CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017911	Pseudomonas fluorescens A506, complete sequence	10 crisprs	DEDDh,DinG,csa3,cas3,RT,PD-DExK	0	2	9	0
NC_021361	Pseudomonas fluorescens A506 plasmid pA506, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_017911_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017911_1

738992-739414

Orphan

Consensus_repeat	Method
ACCGCCAGTGCCGCCGNCANNGCCGCC	CRT

7 spacers

The CRISPR arrays of NC_017911_1

>merge|NC_017911|1|738992-739414|CRT
CGAACCAGTGCCGCCGCCAGTGCCGCCACCAGTACCACCGCCAGTGCCGCCGCCAGTGCCGCCACCAGTACCACCGCCAGTGCCGCCGCCAGTGCCGCCACCAGTACCACCGCCAGTGCCGCCGCCAGTGCCGCCACCAGTACCACCGCCAGTGCCGCCGCCAGTGCCGCCACCAGTACCACCGCCAGTGCCGCCACCAGTACCACCGCCGGTGCCGCCGTCACCACCGCCCGTGCCACCACCGGTTCCACCGCCAGTGCCGCCGTCACCGCCGCCCGTGCCACCACCGGTTCCACCGCCAGTGCCGCCGTCACCGCCGCCCGTGCCACCACCGGTTCCACCGCCAGTGCCACCGCCAGTGCCGCCGTCACCGCCGCCTGTGCCACCACCGGTCCCACCGCCTGTACCGCCGTCACCGCCACC

>NC_017911|1|1|738992-739414|CRT
CGAACCAGTGCCGCCGCCAGTGCCGCC	ACCAGTACCACCGCCAGTGCCGCCGCCAGTGCCGCCACCAGTACC
ACCGCCAGTGCCGCCGCCAGTGCCGCC	ACCAGTACCACCGCCAGTGCCGCCGCCAGTGCCGCCACCAGTACC
ACCGCCAGTGCCGCCGCCAGTGCCGCC	ACCAGTACCACCGCCAGTGCCGCCACCAGTACC
ACCGCCGGTGCCGCCGTCACCACCGCC	CGTGCCACCACCGGTTCC
ACCGCCAGTGCCGCCGTCACCGCCGCC	CGTGCCACCACCGGTTCC
ACCGCCAGTGCCGCCGTCACCGCCGCC	CGTGCCACCACCGGTTCCACCGCCAGTGCC
ACCGCCAGTGCCGCCGTCACCGCCGCC	TGTGCCACCACCGGTCCC
ACCGCCTGTACCGCCGTCACCGCCACC

Protein	Signature genes	Signature genes Name	Protein_function
NC_017911.1\|WP_014716761.1\|743611_744511_+\|serine-protein-kinase-RIO	unknown	unknown	gnl\|CDD\|224632
NC_017911.1\|WP_014716765.1\|747921_748119_+\|heavy-metal-associated-domain-containing-protein	unknown	unknown	gnl\|CDD\|225328
NC_017911.1\|WP_014716753.1\|732017_733223_-\|type-II-and-III-secretion-system-protein-family-protein	unknown	unknown	gnl\|CDD\|227299
NC_017911.1\|WP_038452065.1\|737680_738964_-\|collagen-like-triple-helix-repeat-containing-protein	unknown	unknown	gnl\|CDD\|374271
NC_017911.1\|WP_014716751.1\|729559_730831_-\|CpaF-family-protein	unknown	unknown	gnl\|CDD\|227297
NC_017911.1\|WP_014716749.1\|727779_728667_-\|type-II-secretion-system-F-family-protein	unknown	unknown	gnl\|CDD\|224975
NC_017911.1\|WP_019818340.1\|734523_734721_+\|Flp-family-type-IVb-pilin	unknown	unknown	gnl\|CDD\|226366
NC_017911.1\|WP_014716755.1\|734774_735179_+\|response-regulator	unknown	unknown	gnl\|CDD\|225114
NC_017911.1\|WP_014716754.1\|733242_734187_-\|Flp-pilus-assembly-protein-CpaB	unknown	unknown	gnl\|CDD\|274472
NC_017911.1\|WP_014716760.1\|742199_743477_+\|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl\|CDD\|236440
NC_017911.1\|WP_014716762.1\|744727_745129_-\|Cu(I)-responsive-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133383
NC_017911.1\|WP_014716759.1\|740733_742086_-\|3-oxoacyl-ACP-reductase	unknown	unknown	gnl\|CDD\|236207
NC_017911.1\|WP_014716763.1\|745125_747327_-\|copper-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319783
NC_017911.1\|WP_014716766.1\|748206_749400_+\|multidrug-effflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340878
NC_017911.1\|WP_014716752.1\|730827_732021_-\|Flp-pilus-assembly-protein-TadZ	unknown	unknown	gnl\|CDD\|227298
NC_017911.1\|WP_014716767.1\|749408_749588_-\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_014716758.1\|739882_740731_-\|acyl-dehydratase	unknown	unknown	gnl\|CDD\|366711
NC_017911.1\|WP_014716756.1\|735811_737494_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NC_017911.1\|WP_014716764.1\|747393_747774_-\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_014716750.1\|728668_729550_-\|type-II-secretion-system-F-family-protein	unknown	unknown	gnl\|CDD\|227300

Protein	Function_ID	Function_description	E-value
NC_017911.1\|WP_014716761.1\|743611_744511_+\|serine-protein-kinase-RIO	gnl\|CDD\|224632	COG1718, RIO1, Serine/threonine protein kinase involved in cell cycle control [Signal transduction mechanisms / Cell division and chromosome partitioning].	4.83552e-77
NC_017911.1\|WP_014716765.1\|747921_748119_+\|heavy-metal-associated-domain-containing-protein	gnl\|CDD\|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	5.27182e-11
NC_017911.1\|WP_014716753.1\|732017_733223_-\|type-II-and-III-secretion-system-protein-family-protein	gnl\|CDD\|227299	COG4964, CpaC, Flp pilus assembly protein, secretin CpaC [Intracellular trafficking and secretion].	6.15017e-96
NC_017911.1\|WP_038452065.1\|737680_738964_-\|collagen-like-triple-helix-repeat-containing-protein	gnl\|CDD\|374271	pfam15984, Collagen_mid, Bacterial collagen, middle region. Collagen_mid is the conserved central region of bacterial collagen triple helix repeat proteins.	2.33721e-08
NC_017911.1\|WP_014716751.1\|729559_730831_-\|CpaF-family-protein	gnl\|CDD\|227297	COG4962, CpaF, Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion].	1.81586e-154
NC_017911.1\|WP_014716749.1\|727779_728667_-\|type-II-secretion-system-F-family-protein	gnl\|CDD\|224975	COG2064, TadC, Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion].	1.30671e-13
NC_017911.1\|WP_019818340.1\|734523_734721_+\|Flp-family-type-IVb-pilin	gnl\|CDD\|226366	COG3847, Flp, Flp pilus assembly protein, pilin Flp [Intracellular trafficking and secretion].	3.6296e-08
NC_017911.1\|WP_014716755.1\|734774_735179_+\|response-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	2.55298e-22
NC_017911.1\|WP_014716754.1\|733242_734187_-\|Flp-pilus-assembly-protein-CpaB	gnl\|CDD\|274472	TIGR03177, pilus_cpaB, Flp pilus assembly protein CpaB. Members of this protein family are the CpaB protein of Flp-type pilus assembly. Similar proteins include the FlgA protein of bacterial flagellum biosynthesis.	1.47299e-44
NC_017911.1\|WP_014716760.1\|742199_743477_+\|acetyl-CoA-C-acetyltransferase	gnl\|CDD\|236440	PRK09268, PRK09268, acetyl-CoA C-acetyltransferase.	0
NC_017911.1\|WP_014716762.1\|744727_745129_-\|Cu(I)-responsive-transcriptional-regulator	gnl\|CDD\|133383	cd01108, HTH_CueR, Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators. Helix-turn-helix (HTH) transcription regulators CueR and ActP, copper efflux regulators. In Bacillus subtilis, copper induced CueR regulates the copZA operon, preventing copper toxicity. In Rhizobium leguminosarum, ActP controls copper homeostasis; it detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations. These proteins are comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain winged HTH motifs that mediate DNA binding, while the C-terminal domains have two conserved cysteines that define a monovalent copper ion binding site. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	8.75497e-76
NC_017911.1\|WP_014716759.1\|740733_742086_-\|3-oxoacyl-ACP-reductase	gnl\|CDD\|236207	PRK08261, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional.	0
NC_017911.1\|WP_014716763.1\|745125_747327_-\|copper-translocating-P-type-ATPase	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_017911.1\|WP_014716766.1\|748206_749400_+\|multidrug-effflux-MFS-transporter	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.84252e-107
NC_017911.1\|WP_014716752.1\|730827_732021_-\|Flp-pilus-assembly-protein-TadZ	gnl\|CDD\|227298	COG4963, CpaE, Flp pilus assembly protein, ATPase CpaE [Intracellular trafficking and secretion].	1.88321e-42
NC_017911.1\|WP_014716758.1\|739882_740731_-\|acyl-dehydratase	gnl\|CDD\|366711	pfam01575, MaoC_dehydratas, MaoC like domain. The maoC gene is part of a operon with maoA which is involved in the synthesis of monoamine oxidase. The MaoC protein is found to share similarity with a wide variety of enzymes; estradiol 17 beta-dehydrogenase 4, peroxisomal hydratase-dehydrogenase-epimerase, fatty acid synthase beta subunit. Several bacterial proteins that are composed solely of this domain have (R)-specific enoyl-CoA hydratase activity. This domain is also present in the NodN nodulation protein N.	1.04172e-13
NC_017911.1\|WP_014716756.1\|735811_737494_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	2.86229e-68
NC_017911.1\|WP_014716750.1\|728668_729550_-\|type-II-secretion-system-F-family-protein	gnl\|CDD\|227300	COG4965, TadB, Flp pilus assembly protein TadB [Intracellular trafficking and secretion].	1.53346e-54

>NC_017911.1|WP_038452065.1|737680_738964_-|collagen-like-triple-helix-repeat-containing-protein
MAGTLGTTVGNVGTAVGNLGSTLNGVPIVGATAGGLVTSAGTAVNSIGTGVTAGLGSLGTNTNSLGTTVAGVGNGVADLGGGLSTTGQSLSTTLGGVPVVGGVTGGVGTAVGGVVDKVGTTVTMLGDTLSTASTTGPLGSLTNTLGSKVVVPVVSLVENTTGNLGNATGLGAPLNGVLDKVGSAVTGLGTQVASTGGTGNPVTGIVGTVLTGVGGTLDKSGGYVAPTGGTSAPGLPELVGGLVANVGTGLNVGNTNGTVSAAGVTGGAVGGTVASLGTVLGGTGVANTAATAPVATVAANVGAALNPVTSGVTNLTQTIGTTTGVGAPVNGLVTQVGGAVSSLGTNLTAANANPITNAVGTTVTAVGGTVASVGGLVTGGTTGGTSGGLLGGLNIGTTATATGTATTTGGTTATGGLGGLLNGLTGK
>NC_017911.1|WP_014716756.1|735811_737494_-|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MRVLTPLLLLTLSAYVQAETLPSFLNSNDTVRTLPVPNLPADAYRPPSSKTQVPEAPPTAGQPLLMDTKVTIRKLQIEGGTVYPLAETAQVYAPLIGRETNLAQLIEATRGITRRYQEDGYLLSYAFLPQQNFENGLVRVVLVEGYIKDYQQTGDIGSVSAYVDKLAQKLLAERPLTRKTFERYTTLMSRIPGLSVQAQVPPPGTTDGATHMQIQASRKPFTTSMSLVQKSRGGTQALLSATSNSQTSMGEQLSVSGLFPPGEDKEHYYRVDYNQFINAEGTQLALAAERYRADPNSSVQLDGGFELKPHQSIDRYSIGLSHPFIASPTESLTLGTRLYAVDQTTRYKLVGYPLRFDIESNLRALAVEGDWRKADAQRLRIISGGLYQGIDGLGAKARSDLGVAKPDLDFFRLRLSGVQSDKFFDNWQGVLSGALYWSDNTLPDSERVTFGGQNFGRGYPDDQGSGDKGWGVAYEVNYSFNRTGNWVKILQPYVVVDRAKSWFNDLPVKANDMSSAAVGLRFGDKKYYNIALEAAKPMSDIALDSFNRRPRYTLSFSYQL
>NC_017911.1|WP_014716755.1|734774_735179_+|response-regulator
MSTLLSSRQQILLVDDEEDALIELAESLENEGFVCFTATSVTFALQELTLHPDIALVITDLRMPEESGISLIKRLREHTSRSHLPVIVMSGHAEMDDVSDMLRLQVLDLFRKPIYLARLLDTLNSLFPLSTPGR
>NC_017911.1|WP_019818340.1|734523_734721_+|Flp-family-type-IVb-pilin
MILDLFLKFYIHAQLFLRRRDGASAIEYVIIVAIVALVIVGVGTGLGEKIKGVLDKVVVALTPAA
>NC_017911.1|WP_014716754.1|733242_734187_-|Flp-pilus-assembly-protein-CpaB
MNSRISMVLAGLLLIGALVAGYWGLVLSRPPAPAVAPSPAPVISVEKTVAVVEDQTRQPVVVLVHAVAPFVPLTAADVAVEKLRTVPAGSLTSVDQAIGRTPLRALGAGTWLNDESFTAGGPLARMIRTNERALAVAVDEVIGAGGQLSPGDYVDVLLFLRQDNANAEQSAQVVIPAIRLLSVGDQLGLANDGTPAVPPPATAEERAQAAQRRTAARSVVLAVPEPLLSRLMLASQAGTLRLAVRSADEQLLSRYWAGESDTPDKVQSANRDLYQFTQLALSGPPKKITPAVADTGQRRGVEVIRGAAAAQPTP
>NC_017911.1|WP_014716753.1|732017_733223_-|type-II-and-III-secretion-system-protein-family-protein
MSQRYAQLALALMLPCLPLGMAMGASGNCNTLGQLPAVIEVGEGLQTELQSPVAITRLAIGDPKIADVRVNGDRHFLLTGVGSGATSLMVWTGCSTTPRQSMVFVKGKATSALTSQSLSPSEDPTLPSQVQTDIRFVEVSRTKLKEASTKILGMGNNFFLGSPSLLSPSEGIFKLPVSADSFNIGFGGGRVKALINALESSGFAYTLARPSLVAMSGQSATFLAGGEVPIPVPSAGSDTITIEYKEFGIRLTLTPTVIDHNRIALKVAPEVSELDYNNAIRIEGIQVPALTVRRTDTSVSLADGESFVISGLISSTNRSTIAKLPGLGDIPILGAFFRDSNINSEEKELLMIVTPHLVQPLAANAQLPSLPGEKLRTYDPNWFRLFFLENGNFDRRSGLSQ
>NC_017911.1|WP_014716752.1|730827_732021_-|Flp-pilus-assembly-protein-TadZ
MSDSLSQTFLAITRNSTDLEWLQGALAPLGQVISVGGGSLDELLALVDVTFANLVFVGLDREHLVAQSALIEGALEAKPMLAVVALGDGMDNQLVLNAMRAGARDFVAYGSRSSEVAGLVRRLSKRLPPTAPNAHLGGLTVLYGAQGNTDGALLASHLAMVVQKSGQQTLMLDLGLPRGDSLALLGLDSTFNFGDALRHLRRLDATLINSAFTSTDDGLRILAYAASDEPLEMTSAAELYMLLSALRQHFQHIVVNLTGQADSEALRTFVSHCDKLLWCTDQGVLDCRRNLAVLNLWREKGMKLDHAKLLVDRYIKGCAPDTEALEKSFGLECIAVLPLSPEVRLNAKNQGQSLFTLAPREALTQALRHLGERLAKRTEGLDKPSTRWFERLLGASR
>NC_017911.1|WP_014716751.1|729559_730831_-|CpaF-family-protein
MNGEKLFGAPARGSAAHNDHDGLKLVLHRYIIDAIEESGQNLLEGSRQSLAQFVIDKVAEYITRMHLAISRYEMERLAEEIVDELTGFGPLEVLLRDVSITEILVNGPHRVFIERDGVLHQSDLRFIDAHHVERVMQRILAPLGRRLDESSPMVDARLPDGSRVNAIIPPIALDGPCLSIRKFRKDMLKSSDLVAMQTIDHPIFEFFQEAVGKRCNILISGGTGTGKTTLLNILSQLINPHERLVTIEDVAELQLGHPHVVRLETRPPNAEGHGEVKASDLIRNALRMRPDRIILGEIRGVEVLDVMTAMNTGHDGSMSTVHANNAQDALLRLETLVGLTGRVVAEKTLRQMICAALDVVIQLTRLPDGRRCVSEVVEVVGVRDDVYVTNTLFRLDRRTGFGFLREALNPAGDKLRRESALPL
>NC_017911.1|WP_014716750.1|728668_729550_-|type-II-secretion-system-F-family-protein
MTGLVLLLICILLISLSVWLFQRGLRQAGTDRVLERLSDGQPVAQEPNGSWVALERMFQRAGLGKPTDRLGLWLSGWTAGMLLGYLLAGGLGLLAMLILPPLLLRVYIAWRYQRRVQRMVEQLPQLLDHSVRSLKSGRTLADAVLGAIDSTEAPLKQAMSRIQRNVQMGVSLPESVSDFAEFYERDEFRLFALGLKVNHRYGGNASELLENLIKMIREREQGARQLKAMTGETRMTAYVLAGLPIAMVGYFLMVNPGYLMSMWNDGTGRYLLLAAVALDITGTFVMWRMLRSI
>NC_017911.1|WP_014716749.1|727779_728667_-|type-II-secretion-system-F-family-protein
MAILICILLSLAAVALIVGNLLEQKRRQRLVSQRLQGQLTREDKLGSLMRQLGASAVAQRSVSLDNETQTLLNRVGWRKANQRSMFAAFQIGVPIVLLGLTLLGQQLLFPHAGSPWIAPAVALGIGYLLPKRILALSAKYRQERIAREISTFIPLLRILFESGMAVEQSLRVLSTEAQRLLPDLTHELRLVLARVDSGLELSEELGKTARLLAVDEFTDTCIILQQLIHQGGGAMKSLLALKQLLDDRRLTRLQEYISKMSAKMSVVMMVFLFPALLIVLGGPAMIAISRALNNF
>NC_017911.1|WP_014716758.1|739882_740731_-|acyl-dehydratase
MQWQTLDSTPSLLPLYWRAALKRKITGSTLPERGLRCRISVNPGAVAAYRKVCGFADSPMLPATYPHILAFGLQLQLLTDKTFPFPLLGLIHLRNRIRIHRPLGGVGDVSVGVYARNLSPHPKGATFDIVTVIEDALGLLWEAESQMLCRGVKLEGEALESGLQTPGTLTELTRWKAPTDIGRRYARVSADYNPIHLSAPTAKLFGFPQAIAHGLWNKARTLAALAEHLPAANIEIDVEFMKPVRLPSEVILISSAAGSSGGLELKGAGDIQHMRGKWQPIS
>NC_017911.1|WP_014716759.1|740733_742086_-|3-oxoacyl-ACP-reductase
MSDRYIDFANSSLGHRLVAAIGLPSPVRLERWQAGRLRPVEGALLLGGGALATQVLAFANRLTDAVYSYGAEASTAPAWIPGHGPKLKAVVFDASALQHTEQLKQLREFFQPLLKNLDHSAHLVILGRAPESLSDPFAASAQHALEGFSRSLAKELRSGGVLQLLYVGDGAEDQLEGALRFFLSPKSAYISGQVIRLAACDTPVQDWTRPLAGRKALVTGAARGIGASIAETLARDGAEVIVLDVPQAKADLEALAARLNARTVVLDICAEDAARQLIEHLPDGLDILVHNAGITRDKTLANMTPEYWDAVLAVNLKAAQVLTKALLDNDTLQNNARVVLLASISGIAGNRGQTNYAASKAGLIGLAQAWAPLLKERGISINAVAPGFIETQMTAHIPFALREAGRRMSSLGQGGLPQDVAEAVAWLSQPGSGAVSGQTLRVCGQSLLGA
>NC_017911.1|WP_014716760.1|742199_743477_+|acetyl-CoA-C-acetyltransferase
MTQLRRVAIIGGNRIPFARSNGPYATASNQAMLTAALEGLIERYNLHGLRMGEVAAGAVLKHSRDFNLTRECVLGSRLSPQTPAYDIQQACGTGLEAALLVANKIALGQIECGIAGGVDTTSDAPIGVNEGLRKILLQANRSKSLGDRLKLLLQLRPHHLKPELPRNGEPRTGLSMGQHCELMAQTWQIPRAEQDQLALESHQKMAAAYAEGWHNDLLTPFLGLTRDNNLRPDLTLEKLASLKPAFERSEKGTLTAGNSTPLTDGASLVLLGSEAWAKERGLPILAYLRDGEAAAVDFVHGAEGLLMAPVYAVPRLLARNGLTLQDFDYYEIHEAFAAQVLCTLKAWEDADYCKTRLGLDAPLGSIDRSRLNVKGSSLAAGHPFAATGGRIVANLAKLLDAAGKGRGLISICAAGGQGVTAIIER
>NC_017911.1|WP_014716761.1|743611_744511_+|serine-protein-kinase-RIO
MKTPKRIEPLIEDGLVDEVLRPLMSGKEAAVYVVRCGNELRCAKVYKEANKRSFRQASEYQEGRKVRNSRQARAMAKGSKFGKKETEDAWQNAEVAALFRLAGAGVRVPQPFDFLEGVLLMELVADEYGDAAPRLNDVVLEPDQAREYHAFLISQIVLMLCTGLVHGDLSEFNVLLTPTGPVIIDLPQAVDAAGNNHAFSMLERDVGNMASYFGRFAPELKKTKYAKEMWALYEAGTLHPASVLTGEFDEPEELADVGGVIREIEAARLDEERRQAIRAADDAPPSKVPDEPPPPPWMQ
>NC_017911.1|WP_014716762.1|744727_745129_-|Cu(I)-responsive-transcriptional-regulator
MNIGQAARTSGLSAKMIRYYEAIGLLKTAHRTDSGYRVYGHDDLHTLTFIKRSRDLGFSLEEVGKLLTLWEDRQRASADVKALARQHIDELNHKIRELGQLRDTLQDLMEHCQGDHRPDCPILKELAAGNCCA
>NC_017911.1|WP_014716763.1|745125_747327_-|copper-translocating-P-type-ATPase
MNGSTTFDLPIGGMTCASCAGRVERALGKVPGVQRVSVNLANERAHIEVQGQMDPSVLIAAVDKAGYTATLPQSETATDADQARRLRRERWSLVAGILLALPLVLPMLVEPFGLHWMLPAWIQFALATPVQFILGARFYVAAWKAVRAGAGNMDLLVAIGTSAGYGLSIYEWLTAAPGVTPHLYFEASAVVIALVLLGKYLESRAKRQTASAIRALEALRPERAIRVQDGREEDVAISALKHGDLVLVKPGERFPVDGEVVEGLSHADEALISGESLPVPKQPGDAVTGGAINGEGRLLVRTLALGAESVLARIIRLVEDAQAAKAPIQKLVDKVSQVFVPAVLVLALITVVGWWLYGASLETAIINAVAVLVIACPCALGLATPTAIMAGTGVAARHGILIKDAEALERAHAVSAVVFDKTGTLTSGAPNIAHLAAVDGDEALLLQQAGALQRGSEHPLAKAVLDACREKGLDVADVSASQSLTGRGIAGTLDGRPLALGNRRLLEETGLDAGDLGPRAKEWEAEGRTLSWLIEQGAQPRVLGLFAFGDTLKPGALQAVQQLKALHISSHLITGDNHGSARVVAEALGIDDVHAEVLPAYKAAAVAELKKTGVVAMVGDGINDAPALAAADIGIAMGGGTDVAMHAAGITLMRGDPRLVPAALEISRKTYAKIRQNLFWAFVYNLIGIPLAAFGLLNPVLAGAAMALSSVSVVSNALLLKTWKPKDLEDQRP
>NC_017911.1|WP_014716764.1|747393_747774_-|hypothetical-protein
MRWLFFALAGLMSLPAAAPQALAAEDYAVLIISRERLEVPTHCEIGLYIQDQLAGRLFQEQATAFNLPPGDVSLRLKVLPSQAPGCLPGMLAPPAQNITLKAGDVRKLRIAQGPDGMYLKAAALEY
>NC_017911.1|WP_014716765.1|747921_748119_+|heavy-metal-associated-domain-containing-protein
MQIFSVEGMTCGHCVKAVTQAVQSKDPAASVKVDLAAKEVGVESRLSADDVIGLITEEGYSAKLA
>NC_017911.1|WP_014716766.1|748206_749400_+|multidrug-effflux-MFS-transporter
MNLRIILILGALSAFAPLAIDFYLPGFPAMATAFATDEKHIQLTLAVYFAGLAIGQLIYGPLADRFGRRVPLLSGVTLFTLASFACAYAPSLEWLIGARFVQALGGCAGMVISRAVVSDKCDAVGSAKVYSQLMLVTGLAPILAPLAGGLMVGVWGWQSIFLALSLFSVMAAIAVAVGLPETFPADQPRQPLSGSLRRYGSLLSDRVYLGYALTGGISIAGMFAYIAGSPFVFIKLYGVPAEHYGWLFGSNAAGFILVAQLNARLLAKRGPAFLLSRTVWVYVAAALTLLGIAALRTEALWPLLVPLFICIASLGCILPNTSACAMSGQGARAGSASALLGCIQFGVAAGAASLVGVLHNGTAMPMAMVICLCGVLAVTIAMATQRLQRARAVQAQV
>NC_017911.1|WP_014716767.1|749408_749588_-|hypothetical-protein
MKILIKALAKSPGSQWQVRLDGEAITFRSEAEARAFADTLQARIQAPHRFPLNQQRSAG

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Crispr_ID: NC_017911_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017911_2

2040742-2040848

Orphan

Consensus_repeat	Method
ATCCAACTGTGGGAGCTGGCTTGCCTGCGATGACG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017911_2

>merge|NC_017911|2|2040742-2040848|CRISPRCasFinder
ATCCAACTGTGGGAGCTGGCTTGCCTGCGATGACGGCTTGACAGCCGACGCCTATCTACATGACACCCCGCAATCCAAATGTGGGAGCTGGCTTGCCTGCGATGACG

>NC_017911|2|1|2040742-2040848|CRISPRCasFinder
ATCCAACTGTGGGAGCTGGCTTGCCTGCGATGACG	GCTTGACAGCCGACGCCTATCTACATGACACCCCGCA
ATCCAAATGTGGGAGCTGGCTTGCCTGCGATGACG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017911.1\|WP_014717743.1\|2029880_2031506_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NC_017911.1\|WP_003190068.1\|2049259_2049958_+\|orotidine-5'-phosphate-decarboxylase	unknown	unknown	gnl\|CDD\|234695
NC_017911.1\|WP_014717745.1\|2035586_2036516_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|225531
NC_017911.1\|WP_014717756.1\|2048235_2049000_-\|response-regulator	unknown	unknown	gnl\|CDD\|223816
NC_017911.1\|WP_014717751.1\|2042793_2043237_+\|hotdog-fold-thioesterase	unknown	unknown	gnl\|CDD\|182360
NC_017911.1\|WP_014717744.1\|2033688_2035590_-\|response-regulator	unknown	unknown	gnl\|CDD\|274362
NC_017911.1\|WP_014717742.1\|2028761_2029784_+\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|368185
NC_017911.1\|WP_014717747.1\|2038833_2039859_+\|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|234629
NC_017911.1\|WP_044483131.1\|2036517_2038599_-\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657
NC_017911.1\|WP_014717749.1\|2040213_2040663_+\|phosphohistidine-phosphatase-SixA	unknown	unknown	gnl\|CDD\|224973
NC_017911.1\|WP_014717754.1\|2045091_2045910_+\|DUF4892-domain-containing-protein	unknown	unknown	gnl\|CDD\|374449
NC_017911.1\|WP_014717755.1\|2047204_2048236_-\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|236531
NC_017911.1\|WP_003190033.1\|2031691_2032912_-\|beta-ketoacyl-ACP-synthase-I	unknown	unknown	gnl\|CDD\|181184
NC_017911.1\|WP_014717753.1\|2044134_2044989_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|366166
NC_017911.1\|WP_014717757.1\|2050081_2051089_-\|NADP-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|176190
NC_017911.1\|WP_003190063.1\|2045983_2047048_+\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|182881
NC_017911.1\|WP_014717748.1\|2039869_2040217_+\|DUF4389-domain-containing-protein	unknown	unknown	gnl\|CDD\|379561
NC_017911.1\|WP_014717750.1\|2041113_2042763_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|341255
NC_017911.1\|WP_014717752.1\|2043334_2044138_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_017911.1\|WP_003190035.1\|2032923_2033439_-\|3-hydroxyacyl-[acyl-carrier-protein]-dehydratase-FabA	unknown	unknown	gnl\|CDD\|179953

Protein	Function_ID	Function_description	E-value
NC_017911.1\|WP_014717743.1\|2029880_2031506_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.45619e-65
NC_017911.1\|WP_003190068.1\|2049259_2049958_+\|orotidine-5'-phosphate-decarboxylase	gnl\|CDD\|234695	PRK00230, PRK00230, orotidine-5'-phosphate decarboxylase.	4.87177e-130
NC_017911.1\|WP_014717745.1\|2035586_2036516_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|225531	COG2984, COG2984, ABC-type uncharacterized transport system, periplasmic component [General function prediction only].	8.4504e-32
NC_017911.1\|WP_014717756.1\|2048235_2049000_-\|response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.4331e-75
NC_017911.1\|WP_014717751.1\|2042793_2043237_+\|hotdog-fold-thioesterase	gnl\|CDD\|182360	PRK10293, PRK10293, 1,4-dihydroxy-2-naphthoyl-CoA hydrolase.	1.79885e-47
NC_017911.1\|WP_014717744.1\|2033688_2035590_-\|response-regulator	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	5.17402e-94
NC_017911.1\|WP_014717742.1\|2028761_2029784_+\|amidohydrolase-family-protein	gnl\|CDD\|368185	pfam04909, Amidohydro_2, Amidohydrolase. These proteins are amidohydrolases that are related to pfam01979.	1.00197e-11
NC_017911.1\|WP_014717747.1\|2038833_2039859_+\|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	gnl\|CDD\|234629	PRK00094, gpsA, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.	2.00718e-169
NC_017911.1\|WP_044483131.1\|2036517_2038599_-\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	2.7515e-30
NC_017911.1\|WP_014717749.1\|2040213_2040663_+\|phosphohistidine-phosphatase-SixA	gnl\|CDD\|224973	COG2062, SixA, Phosphohistidine phosphatase SixA [Signal transduction mechanisms].	2.05651e-33
NC_017911.1\|WP_014717754.1\|2045091_2045910_+\|DUF4892-domain-containing-protein	gnl\|CDD\|374449	pfam16234, DUF4892, Domain of unknown function (DUF4892). This family consists of uncharacterized proteins around 270 residues in length and is mainly found in various Pseudomonas aeruginosa species. The function of this family is unknown.	1.75591e-100
NC_017911.1\|WP_014717755.1\|2047204_2048236_-\|HAMP-domain-containing-protein	gnl\|CDD\|236531	PRK09467, envZ, osmolarity sensor protein; Provisional.	8.80122e-45
NC_017911.1\|WP_003190033.1\|2031691_2032912_-\|beta-ketoacyl-ACP-synthase-I	gnl\|CDD\|181184	PRK07967, PRK07967, beta-ketoacyl-ACP synthase I.	0
NC_017911.1\|WP_014717753.1\|2044134_2044989_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	7.07672e-21
NC_017911.1\|WP_014717757.1\|2050081_2051089_-\|NADP-dependent-oxidoreductase	gnl\|CDD\|176190	cd05288, PGDH, Prostaglandin dehydrogenases. Prostaglandins and related eicosanoids are metabolized by the oxidation of the 15(S)-hydroxyl group of the NAD+-dependent (type I 15-PGDH) 15-prostaglandin dehydrogenase (15-PGDH) followed by reduction by NADPH/NADH-dependent (type II 15-PGDH) delta-13 15-prostaglandin reductase (13-PGR) to 15-keto-13,14,-dihydroprostaglandins. 13-PGR is a bifunctional enzyme, since it also has leukotriene B(4) 12-hydroxydehydrogenase activity. These 15-PGDH and related enzymes are members of the medium chain dehydrogenase/reductase family. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES.	0
NC_017911.1\|WP_003190063.1\|2045983_2047048_+\|AI-2E-family-transporter	gnl\|CDD\|182881	PRK10983, PRK10983, AI-2E family transporter YdiK.	7.71645e-69
NC_017911.1\|WP_014717748.1\|2039869_2040217_+\|DUF4389-domain-containing-protein	gnl\|CDD\|379561	pfam14333, DUF4389, Domain of unknown function (DUF4389). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 104 and 223 amino acids in length. There is a single completely conserved residue R that may be functionally important.	6.8723e-29
NC_017911.1\|WP_014717750.1\|2041113_2042763_+\|AMP-binding-protein	gnl\|CDD\|341255	cd05932, LC_FACS_bac, Bacterial long-chain fatty acid CoA synthetase (LC-FACS), including Marinobacter hydrocarbonoclasticus isoprenoid Coenzyme A synthetase. The members of this family are bacterial long-chain fatty acid CoA synthetase. Marinobacter hydrocarbonoclasticus isoprenoid Coenzyme A synthetase in this family is involved in the synthesis of isoprenoid wax ester storage compounds when grown on phytol as the sole carbon source. LC-FACS catalyzes the formation of fatty acyl-CoA in a two-step reaction: the formation of a fatty acyl-AMP molecule as an intermediate, and the formation of a fatty acyl-CoA. Free fatty acids must be "activated" to their CoA thioesters before participating in most catabolic and anabolic reactions.	0
NC_017911.1\|WP_014717752.1\|2043334_2044138_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.56041e-13
NC_017911.1\|WP_003190035.1\|2032923_2033439_-\|3-hydroxyacyl-[acyl-carrier-protein]-dehydratase-FabA	gnl\|CDD\|179953	PRK05174, PRK05174, bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase.	2.63383e-129

>NC_017911.1|WP_014717749.1|2040213_2040663_+|phosphohistidine-phosphatase-SixA
MKVWILRHGEAEGHAPTDAERNLTEHGRAEVLRSAAHLIGQPLGAIIASPYVRAQQTAQLVRDVLGFQPEIRTVPWLTPDGDVQRVLEKLDSDDDVLLVSHQPLVGSLISFLQHGHQRQPQPMYTASLAELEGDFPLAGLMSLVGVKNP
>NC_017911.1|WP_014717748.1|2039869_2040217_+|DUF4389-domain-containing-protein
MNDPKAAPPYESIVLRILWMLVFALVWQVAQFLLGALVVVQLIYRLVYGAPNLGLMNFGDSLSQFLAQIGRFGSFHTEQKPWPFADWPTPRAPEGEAAHSVPPAPHPVRDEEPKL
>NC_017911.1|WP_014717747.1|2038833_2039859_+|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase
MTEQRPIAVLGGGSFGTAVANLLAENGHAVRQWMRDPEQAEAIRVHRENPRYLKGIKIHPAVEPVTDLLDTLTACDLCFVALPSSALRSVLAPHAERLAGKLLVSLTKGIEAHTFKLMSEILTEIAPQARIGVLSGPNLAREVAEHALTATVVASEDEALCERVQAVLHGRTFRVYASADRFGVELGGALKNVYAIIAGMAVALGMGENTKSMLITRALAEMTRFAVNQGANPMTFLGLAGVGDLIVTCSSPKSRNYQVGFALGQGLSLEEAVTRLGEVAEGVNTLKVLKAKAQEVGVYMPLVAGLHAILFEGRTLNQVIELLMRAEPKTDVDFISTSGFN
>NC_017911.1|WP_044483131.1|2036517_2038599_-|TonB-dependent-receptor
MLVCATCAQADDLFLDSQPLPQVLTATRLKQSAAAVPGSMTVIDSELIKASGARDISELLRLVPGMMVDYTSGNQASVNYHGTSASDARRMQVLIDGRSVYRAGLATVDWSDIPVAMEDIERIEVFRGPNTVSYGANALMAVVNILTRSPANSQGSRIKVVRGERGINDFYASQGVGWETGDLRLSLSGQQDDGFDSDAAGADRRDGRRLNRFSLAVSQTLNGQQSLDWQLNVKEGTNQRPYTYTPVFAGITEGGSNSDATAKDYAGSLRWNFDFNPDHSLYIQGSAQQWDRKQIWKACDAKVSFSPELTQLWQLNPNYAEQLARHMDTYSQGSAPPGSAAEQALANQVLGQWRNGANQSVCGDIDQSARESRYDVEIQDTLSLSDSLRLVSGMNYRYDRADSETYFNGTLDDTTWRLFGHLEWRASEHWLLQGGAMYEDTHLSGNSLTPRVAVNYLINPRHGLRAVYSEAIRSPDMFENNVNWSYRVTNLSSPTYGQNAGQYFVVTRGPGNLDKELMRSRELGYNGFFAELGLNVDVKLFYDEITDMISSPLRNNQYIASNANSSRFTGAESQFDWRVSSADRLRLTYAYVDATSSNPLDKAQTARNSGSAGWLREWGQGWSSALFYYGDDALNQYRFQRVDLRVAKRIAVGKTNVELAGMLQQRLDNQPTTWADNNYDHRHVLYFSAELDF
>NC_017911.1|WP_014717745.1|2035586_2036516_-|ABC-transporter-substrate-binding-protein
MADQSRMTRLLVSRLWRRGLLLACLLLAAPAWSASILLTAAEDGAGVRAFTQALAQQRPNDQVSFTPLNELPAPRDLPASTRLILLDLPGLDWRLQDAQGPPALVLRISRLQARQRLGNTHPAKISLLWSDPPLERQLRLIAHILPQAQRVGVLYDAGSEFLLRELMQAAKPIGLEIVPQLWDNTSDSRPLQNLFKNSDVLLGLDDPNLYNPKTVKNLLLSSYARQLPLVGPNAGFVRAGSLASTYSDQADWLAVLDHLLDQPPANWPHTLYPEHFKVVGNPQVARSLGIEQVDEVAVAARLAEGEQRP
>NC_017911.1|WP_014717744.1|2033688_2035590_-|response-regulator
MTLRRRWDINTRTQLITLGPALLLTLLLITFFTFVRIQDLRQELDHTGQLIANQLAPATEYGVISGNNDVLESLLRATLATPHVRFLEIQDSAENILVYVEQPSERHDRSLSVKVFQAPIRLQHIQLNNDFFQDNLNEPKAPRADYLGRVIVGMSNDAFSQRQQEILFKAGILALFALLFTFLLARRLSASLSKPISAMGHAVKAIQQGDYKTPLPIVDDSELGDLSRHINNLAEGLHQASREQQQAMAQLIQTREEAERANNAKSDFLAMMSHELRTPMNGVLGMLQLLETTEMTEEQTEYAALASESTEHLLKVINDILDFSRIERAALELEHIPFNLADLISSCAQAFQHSAQQRGLSLELPIPMGLEALRVRGDPTRIRQILVNLIGNALKFTEHGSVTVEPHWQTLDHELLWFTCTVRDSGIGISAERLDLMFDAFQQADSSISRRYGGTGLGLPIARTLAERMGGTLRAQSEEGRGSVFTLEIPLAIDQQHVPVAAPDALGKASAGDGRHVLLVEDNPVNRTVVEAMLRSLGFEVSLATDGAEAIRSAESLIFTAILMDCRLPLIDGYEATRQIRQLPGCADLPIIALTANALQGDREACLAAGMNDYLAKPFKRTDLQQILQRWVQ
>NC_017911.1|WP_003190035.1|2032923_2033439_-|3-hydroxyacyl-[acyl-carrier-protein]-dehydratase-FabA
MTKQNAFTREDLLRCSRGELFGPGNAQLPAPNMLMVDRITHISEEGGKYGKGELVAELDITPDLWFFACHFEGDPVMPGCLGLDAMWQLVGFYLGWQGLPGRGRALGSGEVKFFGQVLPSAKKVTYNIQIKRVLKGKLNLAIADGSVTVDGREIYTAEGLRVGVFTSTDNF
>NC_017911.1|WP_003190033.1|2031691_2032912_-|beta-ketoacyl-ACP-synthase-I
MRRVVITGLGIVSCLGNDKETVTANLRASRPGIRFNPEYAEMGLRSQVSGSIDLPLEELIDRKIYRFVGHAAAYAYLAMKDAIADSGLSEDQVSNVRTGLIAGSGGASTLNQMEALDILREKGVKRVGPYRVTRTMGSTVSACLATPFQIKGVNYSISSACATSAHCIGTAVEQIQLGKQDIVFAGGGEEEHWSQSFLFDAMGALSTQYNETPEKASRAYDAKRDGFVIAGGGGMVVVEELEHALARGAKIYAEIVGYGATSDGYDMVAPSGEGAIRCMQMAMSTVDTPIDYLNTHGTSTPVGDAKEMEGVRAVFGDKAPKISSTKSLSGHSLGAAGVHEAIYCLLMMEGNFMAGSANIDEIDPVVADMPILTKTVENAKIDTVMSNSFGFGGTNATLVLKRWQGK
>NC_017911.1|WP_014717743.1|2029880_2031506_+|methyl-accepting-chemotaxis-protein
MNIRSLNIAPRAGLGFGVLALMVFVLGGFALLQMANMRQQSDQVETNWLPSVMAVGEMNQDVLRIRALTLRLLVNRDPQAVAQNEQKIAEIKTGLHHAEGVYEALIVLPEERVLFDRFKVEEQQYLQRQEQVVGLSKANRLEDAIAVVNGEMNQMADQMAVTLRELVNLNKSSANEAARLAQQVFSQSRVWVMVMIGVTALITIGLAVWLTRSIVLPLAQSLKVAQGVASGDLTGDIRLSGSDEPARLQQALKRMQESLRDTIRRISESSNQLASASEELSCVTEDATRGLHQQNQEIEQAATAVNQMTVAVEEVASNAVATSQASRESDRIAQQGREQVQQTVVSIEALATDVTANVTQVEALAQKVYGISTVLDVIRSIAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRALAHRTQQSTQEIEQMISGIQQGTDQAVSSMQQSNTRARSTLEIAKSAGMALEEIASAFTLINERNLVIASASEQQAAVAREVDRNLMNIRDLAHQTSTGANQTSAASQELSRLAVDLNSMVARFSV
>NC_017911.1|WP_014717742.1|2028761_2029784_+|amidohydrolase-family-protein
MSGTRLSLALLLAISSLSAQARDYAYSDAHLHYVDFFQESAGMDKLLKAMADNRIEHVMISGIPVAKKWHEDEPKRPRYYAGDDADAYWYSATDVIVAAAVNKLSPAQRQHFHPFLAGFNPNDKNSAAHIQRMLDLNPGLWQGIGEVFTRHDDLTALTSGDTPRANNEAMTRIYHLAAENDLPVLLHSNITSKRERNPLYLAEVEQPLRNHPHTRFIWAHAGTSKEIHRHQVQMEFLLPTLARLLEAYPNLYIDLSWSMLTPYLLDDAGKPRAQWVALVERFPDRFMLGSDVVGRFNKLGKEMRRFDPFLDALPEDVAHKVARDNFLAILPKPPRDGDAR
>NC_017911.1|WP_014717750.1|2041113_2042763_+|AMP-binding-protein
MPVAFRLPLQVFFEREARHPRKVFLVQPIGGGEVQALTWGDVGHQARCAAHWLRARELPQGSHIALISKNCAHWIIADLAIWMAGHVSVPLYPNLTADSVAHVLTHSQARLALIGKLDDWSAMAPGIPAGVPTISLPLCPDGAFDFNWANLQACSPIQDNPLPDADSLATIIYTSGTTGLPKGVMHSFGALGCAATRGTELFGLGEDDRLLSYLPLCHVAERMFVEMASIYTGQTVFFAESLETFLTDLRRARPTALFGVPRIWTKFQLGVYAEIPEKRLDMLLSLPFIGKRVGHKVLAGLGLDALRIALSGAAPVPEALLRWYQRLGLDVLEVYGMTENCGYSHVCRPGGQTLGWIGQPCPGVQVRIDPSGEVQVHSGATMLGYFKDPQKTADTLTADGFLRTGDKGEQDADGRLRLTGRLKEIFKTSKGKYVAPAPIENRLAEHARIEQVCVVGEGLSAPIGLCVLSAPGEDRQALGSGLERWLAQVNAGLDKHERMGQLVVVKDHWAVENGFLTPTLKIKRNVIESTYGPQLQAWSARAETVLWQD
>NC_017911.1|WP_014717751.1|2042793_2043237_+|hotdog-fold-thioesterase
MSLWRTQPNIEHLNAIQKNTIGEMLDIRFESFDDESLTASMVVDHRTHQPYGLLHGGASVVLAESVGSMAAYLCIDASKFYCVGLEVNANHLRGVRSGRVTAVAKAIHIGRTTQVWDIRLSSDEGKASCVSRLTMAVVPLGEQPPAR
>NC_017911.1|WP_014717752.1|2043334_2044138_+|alpha/beta-hydrolase
MSQHVFFTHANGFPSATYGKLFAALAPEYAVAHLPQHGHDPRFPVDDNWQNLVDELIHHLEQQPEPVWGVGHSLGGVLHLHAAMRCPHLYRGVVMLDSPVLTRADRWVIRAAKRFGFIDRLTPAGRTLGRREEFTDLDTARSYFAGKTLFRGFDPDCFDAYLQHGLQQVGDRLRLRFDPATEISIYRGVPHTSPGQVRQLKVPLAVVRGRQSRVVMRHHASGVDRLPMGEMLTMPGGHMFPLERPQDTAALIKNLFARWQARERSCA
>NC_017911.1|WP_014717753.1|2044134_2044989_+|alpha/beta-fold-hydrolase
MSTPVEEVRLSLPHIELAAHLFGPEDGLPVIALHGWLDNANSFARLAPKLHGLRIVALDMAGHGHSAHRPAGAGYALWDYVYDVLQVAEQLGWKRFALLGHSLGAIVSLVLAGALPERVTHLGLIDGVIPPTASGENAAERLGMALQAQLSLQDKRKPVYNSLDRAVEARMKGVVAVSREAAQLLAQRGLMPVPGGYTWRSDSRLTLASPMRLTDEQAMAFVRRVGCPTQLVVAADGMLAKHSELLSQLPFTITTLPGGHHLHLNDEPGAALVADCFNRFFSTP
>NC_017911.1|WP_014717754.1|2045091_2045910_+|DUF4892-domain-containing-protein
MSLGKGCIRALGLCCFSPLVFAADLPGSQDLPAVARQVDAQIVDYRPAEDKERIYPMGAIRKISGQLRYEGQAIARGPATAITYELPAEHSSSAAFTATREALQAKGAQLLFWCKARDCGESSLWANEVFGNAKLVGADGQQEYLLLRLAAPQDNSLVALYGITRGNRRAYLHVEQLDASAPLGNLLPTSATLLRELKSTGELDFPALGAEPDDTWVTLISRALNLDTTLRVSLSGPHTEAWRQALVEKGVRTARLETGAGETQGLHLHLIR
>NC_017911.1|WP_003190063.1|2045983_2047048_+|AI-2E-family-transporter
MLNNDRLLVQILLLVLFGASFWVMAPFWSALFWGAVLAFASWPLMRLLTRWLGGRESLAAGILTLGWMLLVAVPLVWLGFNLADHVRDAVALIKDIQVDGLPEAPTWLGSIPFVGERLVATWDSIDQQGAALMVSIKPYLGQVGNWLLARSAQIGGGILELTLSLVFVFFFYRDGPRLAMFVHRLLERLIGERAGYYIELVAGTVQRVVNGVIGTAAAQALLALIGFLIAGVPGALVLGIVTFLLSLIPMGPPLVWIPATAWLAWKGDYTYAVFLGVWGTFVISGVDNVLKPYLISRGGNLPLVIVLLGVFGGLIAFGFIGLFIGPTLLAVAYSLLTDWSASQAQVRREDKPCN
>NC_017911.1|WP_014717755.1|2047204_2048236_-|HAMP-domain-containing-protein
MRAPFNTLFGRLFGLLLVAIVLAHVLAFFWFHHYGPPPPPRAAFVEQPDGSLTPLRKAPRPWFGGPVVPLTFQFISLIIAAWYGAKLLSRPIQRLSAAAERLSVDLDSPPLVETGPREARQAASTFNLMQKRIREQVSQRARMLGAVSHDLRTPLSRLKLRLEQIEDPKLQGQMRQDLDDMIGMLDATLSYLHEQRTSETRHWLDVQALVESLSENAQDQGRDVQFAGTCTPLQVQPMALRSCLNNLIDNALRYAGTARVELADSRGALVIRVIDHGPGIAADKREAVFEPFFRLEGSRNRNSGGVGLGMTIAREAVERLGGHLSLEDTPGGGLTAVMWLPRV
>NC_017911.1|WP_014717756.1|2048235_2049000_-|response-regulator
MHTPCDPVNEAPKDAVIAEDKRWNTRALIVDDDVPIRELLIDYLARFNILASGVTDGTAMRQAMQAETFDVVVLDLMLPGEDGLTLCRWLRAESDIPILMLTARCEPTDRIIGLELGADDYMSKPFEPRELVARIQTILRRVRDDRTEQRANIRFDTWRLNSVLRQLVADDGLVVPLSNAEFRLLWVFIERPRRVLSREQLLDAARGRSIEAFDRSIDLLVSRLRQKLGDDPKAPQLIKTVRGEGYLFDARDIG
>NC_017911.1|WP_003190068.1|2049259_2049958_+|orotidine-5'-phosphate-decarboxylase
MSVCQTPIIVALDYPTRDAALKLADQLDPKLCRVKVGKELFTSCAAEIVGTLRDKGFEVFLDLKFHDIPNTTAMAVKAAAEMGVWMVNVHCSGGLRMMSACREVLEQRSGPKPLLIGVTVLTSMEREDLAGIGLDIEPQVQVLRLAALAQKAGLDGLVCSALEAQALKNAHPSLQLVTPGIRPTGSAQDDQRRILTPRQALDAGSDYLVIGRPISQAADPAKALAAVVAEIA
>NC_017911.1|WP_014717757.1|2050081_2051089_-|NADP-dependent-oxidoreductase
MTAQTNRQFLLAKRPVGAATRETFTYQEVPVGEPQEGQVLVRNEYLSLDPAMRGWMNEGKSYIPPVGIGEVMRALGVGKVIASKHPNFAVGDYVNGALGVQDYFLGEPRGFYKVDPKLAPLPRYLSALGMTGMTAYFALLDTGAPKTGDTVVISGAAGAVGSIAGQIAKLKGCRVVGIAGGAEKCKFLVDELGFDAAIDYKNEDVPAALKRECPKGVDVYFDNVGGDILDAVLSRLALKARVVICGAISQYNNKEAVKGPANYLSLLVNRARMEGFVVMDHAANFAAAGQEMAGWMAQGKLKSKEDIVEGLETFPETLMKLFNGENFGKLVLKVS

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Crispr_ID: NC_017911_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017911_3

2170569-2170664

Orphan

Consensus_repeat	Method
ATCCAACTGTGGGAGCTGGCTTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017911_3

>merge|NC_017911|3|2170569-2170664|CRISPRCasFinder
ATCCAACTGTGGGAGCTGGCTTGCCTGCGATGGCGGCCTGCCAGCCGACGCTTCTCTACCTGACACCCTACGATCCAATTGTGGGAGCTGGCTTGC

>NC_017911|3|2|2170569-2170664|CRISPRCasFinder
ATCCAACTGTGGGAGCTGGCTTGC	CTGCGATGGCGGCCTGCCAGCCGACGCTTCTCTACCTGACACCCTACG
ATCCAATTGTGGGAGCTGGCTTGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_017911.1\|WP_014717844.1\|2169175_2169691_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|171561
NC_017911.1\|WP_014717852.1\|2176827_2177328_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|171560
NC_017911.1\|WP_014717845.1\|2169860_2170490_+\|LysE-family-translocator	unknown	unknown	gnl\|CDD\|224199
NC_017911.1\|WP_014717843.1\|2168238_2169189_-\|FecR-domain-containing-protein	unknown	unknown	gnl\|CDD\|236622
NC_017911.1\|WP_014717836.1\|2157356_2158538_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340849
NC_017911.1\|WP_014717855.1\|2181029_2182049_+\|type-III-secretion-effector-protein	unknown	unknown	unknown
NC_017911.1\|WP_014717839.1\|2161421_2162333_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|366154
NC_017911.1\|WP_014717850.1\|2175398_2176199_-\|glucose-1-dehydrogenase	unknown	unknown	gnl\|CDD\|187616
NC_017911.1\|WP_014717837.1\|2158537_2160517_-\|LPS-biosynthesis-protein	unknown	unknown	gnl\|CDD\|225747
NC_017911.1\|WP_014717841.1\|2163792_2165232_-\|undecaprenyl-phosphate-glucose-phosphotransferase	unknown	unknown	gnl\|CDD\|274396
NC_017911.1\|WP_014717847.1\|2171726_2172695_+\|DJ-1/PfpI-family-protein	unknown	unknown	gnl\|CDD\|227311
NC_017911.1\|WP_014717846.1\|2170956_2171637_-\|DJ-1/PfpI-family-protein	unknown	unknown	gnl\|CDD\|153233
NC_017911.1\|WP_014717851.1\|2176346_2176748_+\|cytochrome-c	unknown	unknown	gnl\|CDD\|365823
NC_017911.1\|WP_014717848.1\|2172680_2173592_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_017911.1\|WP_019818704.1\|2177354_2178305_+\|FecR-family-protein	unknown	unknown	gnl\|CDD\|226235
NC_017911.1\|WP_014717849.1\|2173579_2175406_-\|glycoside-hydrolase-family-15-protein	unknown	unknown	gnl\|CDD\|225922
NC_017911.1\|WP_014717842.1\|2165647_2168134_-\|TonB-dependent-siderophore-receptor	unknown	unknown	gnl\|CDD\|227114
NC_017911.1\|WP_014717840.1\|2162332_2163793_-\|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|273648
NC_017911.1\|WP_014717854.1\|2178402_2180796_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|227113
NC_017911.1\|WP_014717838.1\|2160587_2161415_-\|polysaccharide-export-protein	unknown	unknown	gnl\|CDD\|224512

Protein	Function_ID	Function_description	E-value
NC_017911.1\|WP_014717844.1\|2169175_2169691_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|171561	PRK12528, PRK12528, RNA polymerase sigma factor; Provisional.	2.00168e-59
NC_017911.1\|WP_014717852.1\|2176827_2177328_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|171560	PRK12527, PRK12527, RNA polymerase sigma factor; Reviewed.	3.11597e-37
NC_017911.1\|WP_014717845.1\|2169860_2170490_+\|LysE-family-translocator	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	7.17944e-33
NC_017911.1\|WP_014717843.1\|2168238_2169189_-\|FecR-domain-containing-protein	gnl\|CDD\|236622	PRK09774, PRK09774, fec operon regulator FecR; Reviewed.	4.22287e-81
NC_017911.1\|WP_014717836.1\|2157356_2158538_-\|glycosyltransferase	gnl\|CDD\|340849	cd03822, GT4_mannosyltransferase-like, mannosyltransferases of glycosyltransferase family 4 and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides.	1.63044e-70
NC_017911.1\|WP_014717839.1\|2161421_2162333_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	4.8495e-18
NC_017911.1\|WP_014717850.1\|2175398_2176199_-\|glucose-1-dehydrogenase	gnl\|CDD\|187616	cd05358, GlcDH_SDR_c, glucose 1 dehydrogenase (GlcDH), classical (c) SDRs. GlcDH, is a tetrameric member of the SDR family, it catalyzes the NAD(P)-dependent oxidation of beta-D-glucose to D-glucono-delta-lactone. GlcDH has a typical NAD-binding site glycine-rich pattern as well as the canonical active site tetrad (YXXXK motif plus upstream Ser and Asn). SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	2.20837e-132
NC_017911.1\|WP_014717837.1\|2158537_2160517_-\|LPS-biosynthesis-protein	gnl\|CDD\|225747	COG3206, GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane].	4.18835e-39
NC_017911.1\|WP_014717841.1\|2163792_2165232_-\|undecaprenyl-phosphate-glucose-phosphotransferase	gnl\|CDD\|274396	TIGR03023, Sugar_transferase., Undecaprenyl-phosphate glucose phosphotransferase. This family of proteins encompasses the E. coli WcaJ protein involved in colanic acid biosynthesis, the Methylobacillus EpsB protein involved in methanolan biosynthesis, as well as the GumD protein involved in the biosynthesis of xanthan. All of these are closely related to the well-characterized WbaP (formerly RfbP) protein, which is the first enzyme in O-antigen biosynthesis in Salmonella typhimurium. The enzyme transfers galactose from UDP-galactose (NOTE: not glucose) to a polyprenyl carrier (utilizing the highly conserved C-terminal sugar transferase domain, pfam02397) a reaction which takes place at the cytoplasmic face of the inner membrane. The N-terminal hydrophobic domain is then believed to facilitate the "flippase" function of transferring the liposaccharide unit from the cytoplasmic face to the periplasmic face of the inner membrane. Most of these genes are found within large operons dedicated to the production of complex exopolysaccharides such as the enterobacterial O-antigen. Colanic acid biosynthesis utilizes a glucose-undecaprenyl carrier, knockout of EpsB abolishes incorporation of UDP-glucose into the lipid phase, and the C-terminal portion of GumD has been shown to be responsible for the glucosyl-1-transferase activity.	3.19294e-164
NC_017911.1\|WP_014717847.1\|2171726_2172695_+\|DJ-1/PfpI-family-protein	gnl\|CDD\|227311	COG4977, COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription].	1.34121e-83
NC_017911.1\|WP_014717846.1\|2170956_2171637_-\|DJ-1/PfpI-family-protein	gnl\|CDD\|153233	cd03139, GATase1_PfpI_2, Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. PfpI is an ATP-independent intracellular proteases which may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.	4.17023e-87
NC_017911.1\|WP_014717851.1\|2176346_2176748_+\|cytochrome-c	gnl\|CDD\|365823	pfam00034, Cytochrom_C, Cytochrome c. The Pfam entry does not include all Prosite members. The cytochrome 556 and cytochrome c' families are not included. All these are now in a new clan together. The C-terminus of DUF989, pfam06181, has now been merged into this family.	5.24579e-06
NC_017911.1\|WP_014717848.1\|2172680_2173592_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.319e-28
NC_017911.1\|WP_019818704.1\|2177354_2178305_+\|FecR-family-protein	gnl\|CDD\|226235	COG3712, FecR, periplasmic ferric-dicitrate binding protein FecR, regulates iron transport through sigma-19 [Inorganic ion transport and metabolism, Signal transduction mechanisms].	1.96276e-67
NC_017911.1\|WP_014717849.1\|2173579_2175406_-\|glycoside-hydrolase-family-15-protein	gnl\|CDD\|225922	COG3387, SGA1, Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism].	4.47326e-113
NC_017911.1\|WP_014717842.1\|2165647_2168134_-\|TonB-dependent-siderophore-receptor	gnl\|CDD\|227114	COG4773, FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism].	0
NC_017911.1\|WP_014717840.1\|2162332_2163793_-\|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase	gnl\|CDD\|273648	TIGR01479, Mannose-1-phosphate_guanylyltransferase, mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. This enzyme is known to be bifunctional, as both mannose-6-phosphate isomerase (EC 5.3.1.8) (PMI) and mannose-1-phosphate guanylyltransferase (EC 2.7.7.22) in Pseudomonas aeruginosa, Xanthomonas campestris, and Gluconacetobacter xylinus. The literature on the enzyme from E. coli attributes mannose-6-phosphate isomerase activity to an adjacent gene, but the present sequence has not been shown to lack the activity. The PMI domain is C-terminal. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NC_017911.1\|WP_014717854.1\|2178402_2180796_+\|TonB-dependent-receptor	gnl\|CDD\|227113	COG4772, FecA, Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism].	0
NC_017911.1\|WP_014717838.1\|2160587_2161415_-\|polysaccharide-export-protein	gnl\|CDD\|224512	COG1596, Wza, Periplasmic protein involved in polysaccharide export, contains SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis].	1.09204e-27

>NC_017911.1|WP_014717845.1|2169860_2170490_+|LysE-family-translocator
MISLVTLGVFSGAVLLLLLSPGPNMAFVISQGVTHGWRGGVASALGIGVADLLLTALTAMGVTALVASWPPAFDLIRYAGVIYLLWLAFKTLQKRPGLDTAHVGRVALGRVFLQAMLNSLLNPKALLFFMVFLPQFVRPEAGPIALQLMVLGGVLTLIASVFHMLLGLFGGALSRFFAKRTKSAWLQKWGLAAVLTALAVRLAVMSRPA
>NC_017911.1|WP_014717844.1|2169175_2169691_-|sigma-70-family-RNA-polymerase-sigma-factor
MSSNHPLDLAAIGQLYQAHHSWLRGWLSRRTGCHERAADLAQDTFVRLLNARQQQTLQQPRAYLSSIARSLMIDQYRRRELERAYLESLAHFAQMEVPSEETRLLILDSLERIDRLLDQLKPRVREAFLLAQLDGLTCPQIALRLGVSKATVERDLSKALHACYRLRYADS
>NC_017911.1|WP_014717843.1|2168238_2169189_-|FecR-domain-containing-protein
MPTPDSRLVDQAIQWMIKLRYNTADDASTAAFEQWLQTSEAHQQAWQRVATLNDDFNHLPAHVSRHALDGARRHISRREGLKMLGLFAGAAGLAWLGRDYTPLPALMADYRTATGERRWVALEDGSKVQLNSASAVDITSSAEQRLVNLRQGEILINTGVDRRPLWVHTRDGYLRALGTRLLVREEPQGTLLAVQQGAVAVFADRHDGTARQVIKPGEQVVFNRSGIRPSPNNGLDPWAWSDGVISAHNMRLEDFLAELGRYRNGLLRCSEAVAGLRVSGTYQLDDTDQVLKLVAQSLAIDVTYRSRYWVTVSARV
>NC_017911.1|WP_014717842.1|2165647_2168134_-|TonB-dependent-siderophore-receptor
MQAFPSKRSPLRHALNATLLGACVAASALPYTASAQEPGSERQARAWNIAPGPLAGALDQFARQAGISLSYDAGSVAGKSSPGLSGTLAPQQALNRLLQGQGLQAQSQGQNAWLLLPQQQAGSTLNLGATTITGDRLGATTEGTGSYTTGAVTIGKGEHSLRRTPQSVSVMTRKLMDDQNITTIDQLLERTPGITSYESPMGGKYFYSRGFKMLGQYQFDGVPLDIGKDYVQADSFSANMAIYDRVEVLKGAAGMLKGAGTASGAVNFVRKRPQDKPTTSLGLSAGTWDNYHAEFDTGGPLNDSGTVRGRAAVSQQNRGSYMDLAKRQDQAFYAALDMDVSPDTTLGFGASYEDVDSTPCWSGLPRYRDGKSLGLSRSTCLGQAWNDWQSQRTTLFADLTHHFNDDWKLKVSAVHSRNLQDIKYAASESTVDYGNPAPTLTSYAALLDYDHKDYGLDAYIDGQFEAFGLQHELILGANGSRGTQDDVYAIRNLPQRQSVFNPNHHFPEPADDTFWPNMYRGGTVKETATQYGAYATLRLRLAEPLMLVLGSRVSWYENRRESLNLAWGEWTDQDARTKETGVVTPFAALIYDLTDNLSVYTSYADIFQPQSSYATVSGSALKPKMGENYELGIKGEWFDGRLNSSLALFRAIEKNAAQTDFETRCGSSSDGYCYTDTGKVRAQGVEAELSGELIERLQVFGGYTYTQTKNLKNIDSAAEGAVSNTYVPRHMLRLWGDYQLDGALSKWTVGAGVNAQSSNYRLQTIKLEQAGYALWNARLAYQVDDTWTVALNGNNLFDKNYYQTVGTSGWGNLYGEPRNLTLSLKGNF
>NC_017911.1|WP_014717841.1|2163792_2165232_-|undecaprenyl-phosphate-glucose-phosphotransferase
MRGKSSVDSLFLTRPGFVEFFVVFVKLIHGLTAVVPAIILLFYPDPVAEHMRNHYLGLLVFFALLTIILFQALGVYSEDLFSNRLRFRVMLVAWVSAFCILLFMYQILLLFPQLSPRNLAAWFSMSLVLFGVERILMLRLYRHLMDNGKFLQRTVILGFTDTAVHVAEHLSRNSDIRSGLIGFIDDRTERIPKELSRLPLLGNTRDLEKLIRSEQVNQVMITLPWAAEQRINGLVKRLRQMSVNVMLVPDMAALRYGHNRITDVGGILMFNTSQLPLRGWSPFIKRCEDLLLASIGLLLLSPVMLVTAIAIKLDSKGPVLFRQKRFGYNDNLIRVFKFRSMYVEQTDLNAENQTTRQDPRITRVGRIIRKTSIDELPQLFNVLLGNMSMVGPRPHATATKAAGIPFEQAVSEYSSRHRVKPGITGWAQINGYRGETDTLFKIQKRVEYDLEYIAKWSVWLDLYIVFMTVPAVLSTKEVY
>NC_017911.1|WP_014717840.1|2162332_2163793_-|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase
MNPLNGLIPCIISGGSGTRLWPVSRQNMPKPFMRMRDDQSLLQKTFLRASHLPGVDSILTVTNRDLLFRTLDDYRAVNTQRLGLDLLLEPFGRNTAAAIAVAALHVQEHFGADAQLLVMPADHLVLDEGAFAQAVEKARALAEAGYLVTFGIQPDRAETGFGYIEQGPALGAGFRVQRFVEKPDQATAQGYLDGGKHLWNAGMFCFKAATLLEELASHAPAVLEAAKAALEHSQSLQNSSSRQRELSPEGFGTAPDISIDVALMEKSAQVAVVPCDIGWSDIGSWEALRQLTPSDDNGNQINGEAILHDVHNCYIDSPKRVLGAVGVRDLIIVDTPDALLIADAHRSQDVRHIVAELKRQNHPAFSLHRTVTRPWGTYTVLEESTRFKIKRIVVKPKGSLSLQMHHHRSEHWVVVSGAAMITNGEREILLNMNESTYIPAGHKHRLTNPGIIDLVMIEVQSGEYLGEDDIVRYDDIYGRAPVEVKP
>NC_017911.1|WP_014717839.1|2161421_2162333_-|glycosyltransferase-family-2-protein
MRTSLIIPTRNAASHLDRLLPALRMQTLQPDEMLVVDSASSDDTVARFREFGARVEVIDARDFNHGGTRRWASEQVGGDALIVMTQDAIPATAETFANLISELQLEPLNGVAYGRQLPHPGAGVLGAQSRHFNYPAASRTKRLDDAAQLGIKTCFSSDSFSVYRRSALSAVGGFPRDVIGSEDAYVAARMLLAGYQVRYAASAQVYHSHDYRLLEEFRRYFDIGVFYGREPWIRQAFGDAGGEGKRYVLAELHALREANALYRAPEVVVRSAFKLLGYRLGHLERHLPNALKRRLGMFSTYWT
>NC_017911.1|WP_014717838.1|2160587_2161415_-|polysaccharide-export-protein
MKTINRRFRLTLLGLLSTSIWLAGCSTPARVPLPDNTTLKAGHQAALTLADLPPPQVLIQSGDSLRIVRDAQEPAAADDMTVFVVRPDGVISVPNIGRVKAALRTPEDLGKEITEKYKRIYREPAVTVNIASAPSNKVFIGGAVSNPAFFDLAGNVSVEQALLSSGGVLPSADASNVALLRTGPDGKYRTYFISLESMLTNPNHPRVALQRGDLIFVPQSGIGATVEAVDMYFTKLFPINKGIGIGLNYDLNKSDVKNSGNTIYNNPTINAGQGL
>NC_017911.1|WP_014717837.1|2158537_2160517_-|LPS-biosynthesis-protein
MIEIRSLRDLLRLFFIYRREFKLAVITTIVVAVLGAFLLPARYESDARLLVKPGRDNTTLPIEAANRQTLIAPSTQHDPIVDEEKMLTGRPIVHIVAERYMAMTAEPPQGFWKVTKFYIKKGVGEVINGIRSVLQFVGLAEKQSPLERLATSLEKNFTAGHEPGSSVIEISFTWDDPAVAQKIVEEWVNAYLEERARILGRKSLHTFYETERAKVAENIQSLKDQLQGRLKQIDSISVDARLKNLTNQIDRVTDAKVSAQNQISGIRSLLANASQQIKSQPADVVTMRETSLNPTQLDLKRQLNALQVERARLLRTYLPGTPQVNQIEQNIRDMEALSAQEATRLERSQNTAPNSLVINVKQQMIDAQLQERKLAGEIENYDKTLAELRAQRDQAMTDEPQLNTLSQQLRTAEKSYALYSDNLEQARIDHELDNSQISNIALIEHATLNPARVFPKSLLMLLFAIPAGVAVGLLTIYVLYLLDQRIHDGTRLQEMFHVPLWSSIPDVQDATPAAVTASLYRLYSLLPLDRIAADGFALGLTSARHGEGVTFITLQLKRLLEERGHRVSVDGASAPTPGEVLLLDASALSSNPQAFLTLRRADQIVLVIEARTSTVPTIENAVSLLTTAFGKVDGMILNRRRFEVPAKVLARLNSWRGAA
>NC_017911.1|WP_014717836.1|2157356_2158538_-|glycosyltransferase
MRIALLAPLPPEQTGIADYAAHLRHALIEQGLEVVTPLAGCLELPEQLKRLQAFDWRGVDLVHAELGGGRFGEFQALEYLRRAQPHLPLTATVHDPERLIWRRAKLFFPLTLLERLPHPLPQAAALLADPLTLHEERRLAKGMRRLITLTRLGGDCLRQRMGLHPQQVAVIAHGNLPIVPQALPPLAPLRLLYFGFIYRGKGIEDLLQALAQSLAAHPQCRSQVRLTLAGGTAPEMTFDPAGNYLDGLREQISALHLEDVVDWQLDLPSAQIPSTIQAHHVMVLPYRESKKLSFLGQMRGTSGALSWANACGRGVITSNARAFAEEVAGGNGITYQQGDTASLSNALSRLILDPQQAQQWAARAGEIGHQRQWANTAQRFAELFRDACEEPLR
>NC_017911.1|WP_014717846.1|2170956_2171637_-|DJ-1/PfpI-family-protein
MTLQIGFLLFPGIQQLDLTGPYDVLGSLPDVKLHLVWKDLAPITSSTGLVFTPTITYADCPNLDVLCVPGGAGVGPLMEDPQTLDFLKAQAQTVRYMTSVCTGSLVLGAAGLLRGRKATTHWAYHHLLAPLGAIPVQERVVRDGNLFTGGGITAGIDFALTLAAELYSEAAAQLVQLQIEYAPASPFDSGRPETAPRHVLEEANKRTVESRRVRGEIVARAAARLG
>NC_017911.1|WP_014717847.1|2171726_2172695_+|DJ-1/PfpI-family-protein
MPKIIHVLAFENAQVLDVTGPLQVFASANDLARQRGLPLPYAVNVIATQAGPVMTSAGLALLAEPLPAIDQPCDTLVIAGGWGVYGVAEDPTLVQWVRDKSLHTRRMASVCTGAFLLAASGLLDGCRVATHWTRCEELARKFPALTVEANPIFIQQGAVWTSAGVTAGIDLCLALVEDDLGRAIALEVARHLVVFLKRPGGQSQFSVTLSLQKSDSRFAELHAWIADNLTLDLSIATLAAQAGMSERSFVRHYRTETGQTPARAVELIRVENARRQLADSTTSIKRIAMQCGFGCEETLRRSFLRALSVTPQAYRERFSPLQ
>NC_017911.1|WP_014717848.1|2172680_2173592_-|alpha/beta-hydrolase
MATVTSPAPLLYVRTTLLDVAYETHGPIDGEPVILLHGFPYDPRGYDDIAPVLAERGYRVLVPYLRGYGPTRFINTQVMRSGQQAALAKDLLDFMDALSIPQATLAGFDWGGRAACIVAALWPQRVRGLVTGDGYNIQAISQSLKPRPPETEHRLWYQYYFHTQRGVDGLTANRRELCQLLWTLWSPSWAEGPSRYALTAPSFDNPDFVEVVIHSYRHRFMYAPGDPALEYIEQALVPQPAISVPSISLCGADDGVGPPPLVDDDVEHFSGFYRRQVLPGVGHNVFQEAPQVTLEALLELLER
>NC_017911.1|WP_014717849.1|2173579_2175406_-|glycoside-hydrolase-family-15-protein
MVDFKNEPQSAIDAHGIIGDMRSAALVNDRGSIDFFCWPEFDSPSVFCALLDTPEAGTFQLTPDLPNARREQIYLPDTNVLQTRWLSDEAVVEITDLLTVSENVDELPLLIRRVRVVSGKATIHLSCAVRHDYARAATEAKAEAASVVFTANGQPGLRLTGSQPLTLQDNTAIATFTLAQDEGAEFVLGGQEDARVTNDCTDLYLERTLKFWRGWISQSNYRGRWREMVNRSALALKLLTSRKHGAIIAAATFGLPETPGGERNWDYRYTWIRDASFTVYAFMRLGFVEEANAYMRWLRGRVSDCCGQPTKINILYGIDGRQELPETTLDHLSGHGGAQPVRVGNEAFDQIQLDIYGELMDAVYLVNKYGEAISHQGWKHTVEVVDQVCEIWNRKDVGIWEMRGEQHHFLHSRLMCWVALDRAIRLASKRSLPAPFARWDQTRQAIYADIWSNFWNEERGHFVQHIGSTALDGSMLLMPLVRFVAATDPRWLATLEAIQKSLVRDGMVYRYRNDDSQIDGLQGVEGAFAACSFWYVECLARAGQVEKAHLEFEQLLRYANPLGLYAEEFDSQARHLGNTPQALSHLALISAATFLDRKLSGEKTVWQP
>NC_017911.1|WP_014717850.1|2175398_2176199_-|glucose-1-dehydrogenase
MQISLQQQVALVTGASSGIGAGAAKALAAAGAAVVLNYNSQAAPAEALAAQINANGGRALAIGGDVSKEADVERLFAQTLDAFGHLDILVANSGLQKDANLVDMTLEDWNTVIGVNLTGQFLCARAAVRIFNRQGVRDGVSRAAGKIIHMSSVHQVIPWAGHVNYAASKGGVEMLMRTLAQEVSEQRIRINGIAPGAIRTAINRAATEGAAEQELLKLIPYGRVGDVEDVANAVVWLASDASDYVVGSTLFIDGGMSLYPEFRGNG
>NC_017911.1|WP_014717851.1|2176346_2176748_+|cytochrome-c
MQAWADTRLIKLLVSGVLAVLSLTQTALCLADNSNGKTLYLQRCAVCHGPDIKGTGPLAQKSNPPTPDLTTAAFKKRLHEYPGVIVSSVILRPNGNLIPKTLQDNGVKIAPHAWSVKDFRDLHQYMSEVISNK
>NC_017911.1|WP_014717852.1|2176827_2177328_+|sigma-70-family-RNA-polymerase-sigma-factor
MTPQPPRRTGFFEHYEELIGTWTRRLRNRQQAEDLAHDTFVRVLESAACEVAQPRAYLHQTARNIAVDAYRREDRRETLTLQVVDHSTPHSSDPEHYMHAIQLADAIERALAELPLNCRRIFIWQKIEGLTQQEIATRLGLSKNMVEKYMIRTLRHLRDRLDASAP
>NC_017911.1|WP_019818704.1|2177354_2178305_+|FecR-family-protein
MDNRVRDEAAQWFVRLQDGPLSAQERQRFDAWRRSQPAHQYEIDVLQGLWSATDLLPKARLQALGDAPTERLGRRALLRYAVAASVVAVAVGLGAYSGLGQPKPYNAEFSTRLGEHRQVTLPDGSVMDLNSRSVVAVRYEKSRRGVELKQGEAMFSVQHDAERPFVVAAGAGQVTVTGTRFDVRREADQTRVAVEAGTVKVQGRASDHIVTLTAGRGTHVDPQGQVAAAYAVNPEELTAWRSGKLVFNNATLVDVAREVSRYREQPLRVSTAAVGNLRLTSVFKSSDTDALLKALPHILPVALRTLPDGSQEIISR
>NC_017911.1|WP_014717854.1|2178402_2180796_+|TonB-dependent-receptor
MKKLALHNNKISRWAPLALAVAISTAQAAEGVHIRAQSLGAALSQLGQQTSLQVFFSPDMVAGKQAPAVDGNLSPEQALRQLLQGSGLDYQIDAGSVTLRPVRSGTGEAGSPLELGVTDIKVVGDWLADADAEVVQNHPGARTVIRREAMVEQGAMNVGDVLRRVPGVQVQESNGTGGSDISLNVGVRGLTSRLSPRSTVLIDGVPAAFAPYGQPQLSMAPISAGNLESIDVVRGAGSVRYGPQNVGGVINFVTRAIPQDFSGEVGTTLQTSAHGGWKHVENAFIGGTADNGIGAALLYSGVNGNGYRNSNNGNDIDDVIFKTHWAPTDQDDFSLNFHYYDASADMPGGLTQKQFDANPYQSVRDWDNFSGRRKDISFKYIRQIDDRTQAEVLTYYSDSFRGSNIANRDLKTLSSYPRTYYTFGIEPRVSHVFDLGPSTQEVSVGYRYLKEGMHEEATSLNLVNNVPTPGGQSDGHVYQDRTGGTEANAFYIDNKIDIGKWTITPGIRFEDIRTEWHDRPVVALNGKRTEEKRREVHNNEPLPALSVMYHVSDAWKLFANYETSFGSLQYFQLGQGGTGDQTANGLNPEKAKTYEVGTRYNDSVWGGEVTLFYIDFSDELQYVSNDVGWTNLGATKHSGIEASAHYDLSNLDPRLDGLTANAGFTYTKATSEGDVPFKGRDLPLYSRQVATLGLRYDVNHWTHNLDVYAQSGQRAPGTGTTYITQGTADGQYGDIPGYVSVNVRSGYDFGAQLSNLKLGVGVKNVFDQQHYTRSSDNNAGLYLGEPRTFFVQASVGF
>NC_017911.1|WP_014717855.1|2181029_2182049_+|type-III-secretion-effector-protein
MSVSMLDTPVSASSTPDLSQASAKAEVKNTRQAAPSFKGQNAAHVNFQSGDNKAGPVFGNPQAPTSAADVRGHHHRPPAMQNFLGQLPHWISHWFFGHRPSMHPGCGHPPPKPNPGCSNPPPRPNPIGSNPPPRPDPTAGRPYPPAPGRPDPQYSLKNREELAQQLRDNFNAFRDPKNPGSISVDSILAMAKRGCSPNPVMNENIRLANELLRRPELMAALDRHGSTGALDGLIDRHSLNAVIKGENYFKYKSDKELAGELLEHFDELKNGSGGSSLKIRDLKKWACQPLTGDAAKDHLIQLSQEIIRKRSDLLEKMDNRASKDDDGKISRTGLYLLSR

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Crispr_ID: NC_017911_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017911_4

2262470-2262573

Orphan

Consensus_repeat	Method
CGATCCAACTGTGGGAGCTGGCTCGCCTGCGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017911_4

>merge|NC_017911|4|2262470-2262573|CRISPRCasFinder
CGATCCAACTGTGGGAGCTGGCTCGCCTGCGATGGCGGCCTGCCAGGCGACGGCTATCTACCTGACACCCCACGATCCAACTGTGGGAGCTGGCTTGCCTGCGA

>NC_017911|4|3|2262470-2262573|CRISPRCasFinder
CGATCCAACTGTGGGAGCTGGCTCGCCTGCGA	TGGCGGCCTGCCAGGCGACGGCTATCTACCTGACACCCCA
CGATCCAACTGTGGGAGCTGGCTTGCCTGCGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017911.1\|WP_014717951.1\|2264446_2265097_-\|DUF480-domain-containing-protein	unknown	unknown	gnl\|CDD\|377312
NC_017911.1\|WP_014717952.1\|2265214_2265724_+\|DUF1993-domain-containing-protein	unknown	unknown	gnl\|CDD\|370447
NC_017911.1\|WP_014717949.1\|2260649_2260844_-\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_044483165.1\|2266008_2269164_+\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_161793214.1\|2254618_2255938_+\|TRAP-transporter-large-permease-subunit	unknown	unknown	gnl\|CDD\|224967
NC_017911.1\|WP_014717956.1\|2271856_2272759_-\|transcriptional-activator-NhaR	unknown	unknown	gnl\|CDD\|176120
NC_017911.1\|WP_014717957.1\|2272893_2273145_+\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_074059269.1\|2262766_2264068_+\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NC_017911.1\|WP_014717958.1\|2273176_2273926_+\|TerC-family-protein	unknown	unknown	gnl\|CDD\|223930
NC_017911.1\|WP_014717948.1\|2259304_2260372_+\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NC_017911.1\|WP_014717946.1\|2256117_2257797_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NC_017911.1\|WP_014717947.1\|2257819_2259133_-\|tRNA-5-hydroxyuridine-modification-protein-YegQ	unknown	unknown	gnl\|CDD\|237969
NC_017911.1\|WP_014717944.1\|2250799_2252113_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|340430
NC_017911.1\|WP_014717954.1\|2269235_2270456_-\|serine/threonine-transporter-SstT	unknown	unknown	gnl\|CDD\|184190
NC_017911.1\|WP_014717955.1\|2270697_2271852_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NC_017911.1\|WP_019818659.1\|2261077_2261452_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371451
NC_017911.1\|WP_014717959.1\|2274019_2275054_+\|selenide,-water-dikinase-SelD	unknown	unknown	gnl\|CDD\|234870
NC_017911.1\|WP_014717950.1\|2261608_2262427_+\|shikimate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|183587
NC_017911.1\|WP_003190283.1\|2260375_2260558_-\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_014717945.1\|2252241_2254389_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910

Protein	Function_ID	Function_description	E-value
NC_017911.1\|WP_014717951.1\|2264446_2265097_-\|DUF480-domain-containing-protein	gnl\|CDD\|377312	pfam04337, DUF480, Protein of unknown function, DUF480. This family consists of several proteins of uncharacterized function.	2.76847e-73
NC_017911.1\|WP_014717948.1\|2259304_2260372_+\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	1.91269e-43
NC_017911.1\|WP_161793214.1\|2254618_2255938_+\|TRAP-transporter-large-permease-subunit	gnl\|CDD\|224967	COG2056, COG2056, Predicted permease [General function prediction only].	0
NC_017911.1\|WP_014717956.1\|2271856_2272759_-\|transcriptional-activator-NhaR	gnl\|CDD\|176120	cd08429, PBP2_NhaR, The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold. NhaR is a positive regulator of the LysR family and is known to be an activator of the nhaA gene encoding a Na(+)/H(+) antiporter. In Escherichia coli, NhaA is the vital antiporter that protects against high sodium stress, and it is essential for growth in high sodium levels, while NhaB becomes essential only if NhaA is not available. The nhaA gene of nhaAR operon is induced by monovalent cations. The nhaR of the operon activates nhaAR, as well as the osmC transcription which is induced at elevated osmolarity. OsmC is transcribed from the two overlapping promoters (osmCp1 and osmP2) and that NhaR is shown to activate only the expression of osmCp1. NhaR also activates the transcription of the pgaABCD operon which is required for production of the biofilm adhesion, poly-beta-1,6-N-acetyl-d-glucosamine (PGA) .Thus, it is suggested that NhaR has an extended role in promoting bacterial survival. This substrate-binding domain has significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	8.39283e-121
NC_017911.1\|WP_074059269.1\|2262766_2264068_+\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	3.83426e-07
NC_017911.1\|WP_014717958.1\|2273176_2273926_+\|TerC-family-protein	gnl\|CDD\|223930	COG0861, TerC, Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism].	4.27189e-75
NC_017911.1\|WP_014717946.1\|2256117_2257797_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	4.49901e-75
NC_017911.1\|WP_014717947.1\|2257819_2259133_-\|tRNA-5-hydroxyuridine-modification-protein-YegQ	gnl\|CDD\|237969	PRK15452, PRK15452, putative protease; Provisional.	0
NC_017911.1\|WP_014717944.1\|2250799_2252113_+\|sensor-histidine-kinase	gnl\|CDD\|340430	cd16954, HATPase_PhoQ-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.	5.58716e-49
NC_017911.1\|WP_014717954.1\|2269235_2270456_-\|serine/threonine-transporter-SstT	gnl\|CDD\|184190	PRK13628, PRK13628, serine/threonine transporter SstT; Provisional.	0
NC_017911.1\|WP_014717955.1\|2270697_2271852_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	5.55614e-78
NC_017911.1\|WP_019818659.1\|2261077_2261452_-\|hypothetical-protein	gnl\|CDD\|371451	pfam11285, DUF3086, Protein of unknown function (DUF3086). This family of proteins with unknown function appears to be restricted to Cyanobacteria.	0.00387162
NC_017911.1\|WP_014717959.1\|2274019_2275054_+\|selenide,-water-dikinase-SelD	gnl\|CDD\|234870	PRK00943, PRK00943, selenide, water dikinase SelD.	0
NC_017911.1\|WP_014717950.1\|2261608_2262427_+\|shikimate-5-dehydrogenase	gnl\|CDD\|183587	PRK12550, PRK12550, shikimate 5-dehydrogenase; Reviewed.	0
NC_017911.1\|WP_014717952.1\|2265214_2265724_+\|DUF1993-domain-containing-protein	gnl\|CDD\|370447	pfam09351, DUF1993, Domain of unknown function (DUF1993). This family of proteins are functionally uncharacterized.	4.8924e-89
NC_017911.1\|WP_014717945.1\|2252241_2254389_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	4.22156e-80

>NC_017911.1|WP_014717950.1|2261608_2262427_+|shikimate-5-dehydrogenase
MQMHPNKDTQLCMSLSARPGNFGLRFHNHLYEQLGLNFYYKAFSSQDLPGAIGGIRALGVRGCGVSMPFKEAAIALVDELDDSVQAIDSLNTIVNTNGHLKAYNTDYIAIEQLLKKHAVPKDSSFALRGSGGMAKAVASALRDGGYANGVIVARNEVAGQALARNLGYAWQADLGSLRPQMLINVTPIGMTGGAEADALAFDAEAIDQAETVFDVVAIPAETPLIVRGRAQGKRVITGLEVIAIQALEQFVLYTGVRPTQEQFEAAVAFARS
>NC_017911.1|WP_019818659.1|2261077_2261452_-|hypothetical-protein
MTIMRKLPRIALLIGALAMAGQASAHGGGWGGPAVFGALVGAAVVGSVVASQPREVYVQQPVYVQPQPVYAAPPPVYYAPPPPVYVQQQVYYRPAPVYYGPPRGYYGPPRGYYGPPHGYYRHGW
>NC_017911.1|WP_014717949.1|2260649_2260844_-|hypothetical-protein
MPTQNPHRTAGLCTSSKVYNALTELKHLEGHRSAKFLALLAENLVRKGLLSEHEVVNMLDQVVD
>NC_017911.1|WP_003190283.1|2260375_2260558_-|hypothetical-protein
MPTVQIMSVIGSAVPAPLRKLGLLACWYVVRDGEPISGPLTSLSDAETQRRMATDFRLEA
>NC_017911.1|WP_014717948.1|2259304_2260372_+|AI-2E-family-transporter
MNQTNLQFKTLLLLLALVTVAFIWILLPFYGAVFWAVILGIIFAPMQRRLQQRFSWNRNLTSLTTLMVCLVIAILPVIITSALLVQEGATLYKNIESGKLDVAGYIEQFKNVLPPYFQQLLDRFGMGNLEGLREKVVKGAMQGSQFFASQAFSFGQGTFDFLVSFFIMLYLLFFLLRDGPELVRKVRAAVPLAEPQKRRLQLKFNRVVRATVKGNVLVAVTQGALGGLIFWFLDIPSALLWAVLMAFLSLLPAVGAGLVWGPVAVYFLLSGSIWQGVVLGLFGVFVIGLVDNVLRPILVGKDTKMPDYLILISTLGGLSVFGLNGFVIGPLVAALFMSCWALFVETKPRVKLPLP
>NC_017911.1|WP_014717947.1|2257819_2259133_-|tRNA-5-hydroxyuridine-modification-protein-YegQ
MPSMIAPELLAPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFDHANLALGIQEAHDQGKRFYVVVNIAPHNAKLKTFLKDLAPVIAMGPDALIMSDPGLIMLVRQHFPQMPIHLSVQANTVNWASVAFWQQQGICRVILSRELSLEEIGEIRQQVPAMELEVFVHGALCMAYSGRCLLSGYMNKRDANQGTCTNACRWKYQATPAVENATGDIVHEYQPTLGIGTPTDKVFLLQEANRPDDPMPAFEDEHGTYIMNAKDLRAVQHVERLAQMGVHSLKIEGRTKSHFYCARTTQVYRQAIDDAVAGRAFDRGLMTNLESLAQRGYTEGFLRRHVHDEYQNYQNGSSVSERQQFVGELTGERRGALAEVKVKNRFALGDHLELMTPAGNFHFDLPSLHNAKGESIEVAPGDGHTVYVPIPAQMDLRFGLLMRDV
>NC_017911.1|WP_014717946.1|2256117_2257797_+|methyl-accepting-chemotaxis-protein
MRLSLKAKVLALAVVPVLLFAVVISLTTVWILQGQARNEVDETRQRLLNDAKATLQGYVEVAMNTIKPLYDAAAPGDSAARAQVVKLLSNTSYGKDGYFFGYDSETIRLFKGNSPDGVGKSFKDNRDPNGVYVNRDLVKVGKDGTHYLQYSSTQPGQTELVPKLGYTEYLPKWDMVIGTSVNLDGIDAQVAVVQAKVEKRMQGVLLSILGVAVVVLLVIAAVGMLLANTILRPLHLMKANLDDIAAGEGDLTRRLAITSQDELGDLAGAFNRFVDKIHGLVRQITDMTAQLTGLVSQVSDQAQRSEQAMERQRHETDQVATAINQMSSAAHEVARSAQGAAVAAQQTDAEGQAAKRVVDGSIAQIHALVNDIRSSGVSLDSLQQDVSSIVSVLGVIRSIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRALASRTQTSTQEIQGMIDRLQKGTEAAVDAMRRSSDAGDGTSAQANQAGASLDTMAQLIGTINSMNAQIASAAEEQTAVAEEINRSVHQIAVAVDSVADETQLGAQTSRSLADLGQRLGQLVGQFRI
>NC_017911.1|WP_161793214.1|2254618_2255938_+|TRAP-transporter-large-permease-subunit
MNAVIAAVGTMLVLSLSRVHVVIAIIVGALVGGLTGGLGIEATLKAFNGGLGGGATVALSYALLGAFAVAIAKSGLAHALADKALLLVDRQDASGGNHVKWLLIGLLWVVAIASQNILPIHIAFIPLLVPPLLYVLTKLQLDRRLIACVMTFGLITPYMFLPVGFGNIFLNQILLANVAKSGVDISGVNVTHAMGLPALGMVVGLLVAVLISYRKKRVYDLKKIERVEQVAVQYNPLTLLVAGLAIASAFIIQLWLDSMIIGALAGFLIFSVSGIVRWRDTDDLFTEGMKMMAMIGFIMIASSGFAEVLKATGDVNSLVQASAAFIGHSRGVGALLMLLVGLLVTMGIGSSFSTVPILAAIFVPLCVQLGFSPVAIVCIVGTAGALGDAGSPASDSTLGPTSGLNIDGQHHHIWDTVVPTFLHYNLPLLAFGWLAAMTL
>NC_017911.1|WP_014717945.1|2252241_2254389_-|methyl-accepting-chemotaxis-protein
MSLRQLSIQWKITLLAGLCLLGIVTLLVGLSLYRMAQSSQQVKASSMQMLDEAAQSRIEAQGEVQALGIRQQFMDAYQYGHGFSRQVLFLREQAEKRFLDAFDTREDLTRQVKAALQANPDLLGLSLVFEANALDGKDELFANQAELGSNDKGRFALYWSQPTPGKITSMALPESDMADTSIGPSGEKANAWFTCPRTTLKPCVIEPYFYVIDGQNVLMTSIVFPLMVNGKVIASLSVDINLNSLQAVSQQASQKLYDGQTQVSILSPTGLLAGYSPDASKLSQRLEQVDPASGAQLTSALASSTQTHSLRTDHQLKVLAPFAPIPGGKAWGVLLDVPEKVLVAPAEALKNQLDADNAKGTLLELGLGLLAAVVGLILVWLMARSVTRPILGVAHMLEDIASGEGDLTRRLAYAKQDELGQLAGWFNRFLDKLQPIIAEVKRSVQDARGTADQSAAIATQTSAGMEQQYRQVDQVATASHEMSATAQDVARSAAQAAQAARDADQATRQGLTVIDRTTANIGDLAADMSTAMTQVEGLAANSEQIGSVLEVIRGIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLARRTQESVEETRLVIEQLQTGTSDVVGSMGNSYRQAQGSVEQVGQAVTALRQIGDAVTVISDMNLQIASAAEEQSAVAEEINSNVATIRDVTESLSEQANESARVSQALNSLANQQQGLMDQFRV
>NC_017911.1|WP_014717944.1|2250799_2252113_+|sensor-histidine-kinase
MRSIQRRLSLGLISVMVIVGVVLAQTSLWLFEAGLQRYLEAGLRNDSENLLVALVRGPNGVQLDEQRLSPAYQRPFSGHYFRIDFADVHWRSRSLWDQELPRLPVAGLKGNLQLGPEGQQLLVLRSDYKRFGQSISISVAQDYTPVRESFRLMRQVGLVMGLAALLLVLILQRVTVRRALRPLETARNQIAQLQQGQRSQLDTQVPLELEPLVAQINHLLAHTEDSLKRSRNALGNLGHALKTPLAVLLSAASSDALKDHPQLSQLLREQLEQVQQRLNRELNRARLAGDALPGALFDCEQELPGLLATLRMIHGEHLDLSYQVAPGLQLPWDREDLLELLGNLLDNACKWADAEVRLSVSETPQGYRLAVEDDGPGIPEAQRDQVFSRGARLDEQRVGHGLGLGIVRDIVEVWGGVLQLQESELGGLKVLIQLPRR
>NC_017911.1|WP_074059269.1|2262766_2264068_+|IS4-family-transposase
MAKLALQQAIAPEWIDQVFEEHRQRQYSRELLFSTIIKLMSLVSLGLKPSLHAAARQLEDLPVSLAALYDKISRTEPALLRALITGCAQRLAPTIRELGCTAMLPGWQVRVVDGNHLASTEKRLGALRNERGAARPGFSVVAYDPDLDQVVDLQACEDAYASERVCVLPLLANAEPGQVWLADRLYCTLPVMEACEQVQTCFVIRQQAKHPRLIQEGEWQEPVPVETGTVREQIIQVKGGYQCRRVELTLHSPTDSGDSSLMFWSNLPESVSAQQIAELYRRRWSIEGMFQRLEAILESEIETLGSPKAALLGFATAVLAYNVLAVLKRSVEQAHRDTQPEGWEASIYHLAVQVRSGYEGMQIALPSEHFPVIPLEKLAQHLLALARNIQPKQVAKSPRGPKVPKPKTWVKGTAVNAHVSTDRIIKAAKTKRP
>NC_017911.1|WP_014717951.1|2264446_2265097_-|DUF480-domain-containing-protein
MTAEHDTDTPEPRLNSTEIRILGCLIEKQATNPETYPLTLNALVLACNQKTSREPVMNLSQGQVGQSLRALEGQGFTRLVMGSRADRWEHRVDKALELVPAQVILTGLLFLRGPQTVNELLTRSGRMHDFEDAEQVVHQLERLIARGLALLVPRQAGQREDRYTHALGDPADIEAIMTARGNPVERSAGAVSVERIEELEARIAALEERLAQLEQG
>NC_017911.1|WP_014717952.1|2265214_2265724_+|DUF1993-domain-containing-protein
MTISLYAASIPVFKQMLNALSDVLNKAEAHASAKNIEPNALLQARLFPDMFPLVRQVQIAVDFAKGVSARLAEIEVPKYEDNEVTFADLQALIAKVLAFVDTIKPEQIDGKEGIEIITRPGTPKEKRFSGQSYLLTYGLPQFFFHITTAYALLRHNGVEVGKRDYMGAF
>NC_017911.1|WP_044483165.1|2266008_2269164_+|hypothetical-protein
MSRTRREAPGNEAVLSTSDRAQADSELAARYAEALESRARDEHTIIPNIPDASSLGQWRTQLRNTFEDPYLAYVLKRQGLDPTTMEIAPDGTLSVKEKNGAIARFTLKDHPRWALYAGPILAALKAYAPDGISYSAVRAESVPLKLIAQFYGETIHNDSTEDRARAQALQKNNAFATSGVGQARSEETLMLQKQQLADRRDLQAFQDALVEANAKVGKYLDQQERLHQSNLSFRPGFQPPYDREAGFLSYLQSQLFTIGPESGFHLDNQPMAGRQVNLLQFMTANGWKHPVNTEEMRQIGLSLAELQYPQRRQDLGGGLAWPTPLDTTQQQAIYDAVSYNAMGLPEFDQLKLSQNAFGYLTQTIQWSEAELKDPRQAILRLLQSPAAQSLGEALRDKFEGVGSVEDWVLSALQIGLNQDALWKPGEKNKVAGFDLSARENWGKPLSFVLKGLTDHLSKSYGGNAPVAAYLPLSHHAPELLVKDVPDHVTYGSPGWVSLKSIVAKAEMRSPGVAATKTYEQLLKDDLRPIDDAGIQVEALAAREGLIHWAVADGAIEKREDNNYTDEEIERAGVLANERFELLTTASEAQRTILHSRSELGLSILRAHFPEETYGKIDFEKKTIYPTEKHRDLKGPYSILDIYSAPQQHVRWFSNDPAVPIEKIAADVREMESLNEAFESHVLEYFDGFKDAMSVNVKHQMSLLPQEDQEALQHGALKIYGEEKVTQTITSAGYKIQYDVSETEEVKSSSVFLETLHKGKKRIYEFNPATGGLQHRADLAEGLKTGLQGEWSPVATNKPKVRVRSNTKISEINANDSAERKERESKLQTSSPTQAFSSQRTQHIADAVTRHFFRADERETVVNAARGVTTFDTEVTEFEKIQAVTRALIPGASALHSFQQGRIGEGLTFLAFDVFGFVVAGAGAVGKISKIAKVGGQLGRGGVTGRLGRALISAANPFAGGAAIGTRGLTTFSSILGKGSLGWKIIAANRSVDRVFKHKPKNVTVGTSPGEDATKIMAQLDTVTGKWYRFNPQTNERYGMPLQGFTAATSPP
>NC_017911.1|WP_014717954.1|2269235_2270456_-|serine/threonine-transporter-SstT
MTAAPSLLQRLMRVSLVTQIVIGLIAGIVLALLFPEAARATGFIGKVFVTALKAVAPILVFVLVMASIANHKHGQETHIRPILFLYLLGTFSAAVVAVVASMLFPSALVLVTHDATVSAPGGIGEVLQSLLLSVVDNPVSALMNANFIGILAWAIGMGIAIRHAGETTRTVLDDLSNGVTLIVRVVIRFAPLGIFGLVASTLATSGFGALLGYAHLLVVLIGCMLFVALVINPAIVFWKLRRNPYPLVLMCLRESGITAFFTRSSAANIPVNLALSKRLGLHEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGITVDLPTAVLLSVVAAICACGASGVAGGSLLLIPLACSLFGIPSEIAMQVVAVGFIIGVLQDSAETALNSSTDVLFTAAACLGKEDQTA
>NC_017911.1|WP_014717955.1|2270697_2271852_+|MFS-transporter
MLFPILMLSAAGFTVLTTEFVIVGLLPSIARDLNVSVSQAGLLVTLFAFTVAAFGPFLTAYCARFPRKRLFISILIMFAAANTVAALAPNIWVMALARLIPALGLPVFWALASETAVDIVGPEFAGRAIEKIGFGIVCATVFGIPVGTLISDMFGWRTAFAVLAVIALAKALLLYVYLPVTPAKHQQASLRSQFKILRSPVMQGHILLSILVFSGMFTAYTYLADILERLAGFDGTLVGWCLMGFGAVGLIGNSLGGRAVDRHPLIASMVFCGFMIAGMVAVVPAIHSTIGLAAAMAVWGVTQAAMFLVSHVRLMKAAPHAPAFAASLNIAGANLGIGLGAMVGGHVIDTLGLGSLGFAASGFILVSILLALWLMTAKPTALNA
>NC_017911.1|WP_014717956.1|2271856_2272759_-|transcriptional-activator-NhaR
MLNYRQLHYFWVVAKTGSIVRACEQLNLTPQTISGQISLLEQTFGIALFQRVGRQLELTEAGRQALPYAEQMFQTGNELEAMLRAQPDEQQIPFRVGVADVVPKSIVYRLIAPTMELSEPIRITCREDKLERLLADLAIQRLDLVISDSPMPTHLDIKGYSQKLGECGISFFATQTLADQHGGDFPQCLQGAPLLIPGAETVVRSRLQRWFAEQQIQPRIIGEFDDSALMQAFGQSGSGIFIAPSVIADEVVRQYGVALIGQTDAVTESFYAISVERKVKHPGIVAITEGARRELFTALP
>NC_017911.1|WP_014717957.1|2272893_2273145_+|hypothetical-protein
MKLNSLGAASLLALSLIGVSGCDQVEKSAQQVLGKATESAKQAIDDTHKAAEQALSEATQGLISPEKQEKDAENAAESDTKET
>NC_017911.1|WP_014717958.1|2273176_2273926_+|TerC-family-protein
MDYLLQLAASPTAWVALATLIVMEIVLGIDNLIFISILTNKLPEKHRAKARRIGISMALILRLGLLSTIAFIVQLTTPVFEVFGQAFSWKDMILIAGGLFLVWKATTEIHHSMDPEPEEKATVSNTVTIGFAAAIGQILMLDLVFSIDSIITAVGMTEHLPIMIIAVVVSVIVMLVAAEPLAKFINDNPTVVMLALGFLIMIGMTLIAEGFGAHVPKGYVYAAMAFSAAIECLNIARRNRHARLLAARQ
>NC_017911.1|WP_014717959.1|2274019_2275054_+|selenide,-water-dikinase-SelD
MNEPIRLTQYSHGAGCGCKISPQVLEVILAGSGAQNLDPNLWVGNASRDDAAVYAIDDERGVVSTTDFFMPIVDDPFDFGRIAATNAISDIYAMGGDPLMAIAILGWPVNVLAPEIAREVIRGGRAVCDAAGIPLAGGHSIDAPEPIFGLAVTGIVQKRHMKRNDTATAGCRLYLTKPLGIGILTTAEKKGKLREADIGLARDWMCTLNKPGSRFGKLAGVMAMTDVTGFGLLGHLVEMADGSGLTARIDYAKVPRLPGVEYYLDQGCVPGGTLRNFESYASKLGRVQELHKRVLCDPQTSGGLLIAVTPEGDAEFHAVAAELGLALEPIGELLERQTNAVEVI

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Crispr_ID: NC_017911_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017911_5

2419073-2419173

Orphan

Consensus_repeat	Method
TCCAACTGTGGGAGCTGGCTTGCCTGCGA	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NC_017911_5

>merge|NC_017911|5|2419073-2419173|CRISPRCasFinder
TCCAACTGTGGGAGCTGGCTTGCCTGCGAAGACGGCCTGCCAGCCGACGCATTTCTACCTGACGCCCCGCAATCCAACTGTGGGAGCTGGCTTGCCTGCGA

>NC_017911|5|4|2419073-2419173|CRISPRCasFinder
TCCAACTGTGGGAGCTGGCTTGCCTGCGA	AGACGGCCTGCCAGCCGACGCATTTCTACCTGACGCCCCGCAA
TCCAACTGTGGGAGCTGGCTTGCCTGCGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017911.1\|WP_014718073.1\|2428453_2429440_+\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380482
NC_017911.1\|WP_003190545.1\|2415190_2415490_-\|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|378968
NC_017911.1\|WP_172832686.1\|2413297_2414149_+\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_014718064.1\|2409995_2411939_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NC_017911.1\|WP_014718069.1\|2421683_2423420_-\|dihydroxy-acid-dehydratase	unknown	unknown	gnl\|CDD\|235708
NC_017911.1\|WP_014718071.1\|2425953_2427534_+\|aldehyde-dehydrogenase-(NADP(+))	unknown	unknown	gnl\|CDD\|143447
NC_017911.1\|WP_014718074.1\|2429436_2430939_+\|L-arabinose-ABC-transporter-ATP-binding-protein-AraG	unknown	unknown	gnl\|CDD\|183077
NC_017911.1\|WP_014718062.1\|2406071_2407334_-\|carbohydrate-porin	unknown	unknown	gnl\|CDD\|335962
NC_017911.1\|WP_014718068.1\|2416861_2418991_+\|TonB-dependent-siderophore-receptor	unknown	unknown	gnl\|CDD\|236643
NC_017911.1\|WP_014718075.1\|2430948_2431917_+\|L-arabinose-ABC-transporter-permease-AraH	unknown	unknown	gnl\|CDD\|183076
NC_017911.1\|WP_003190542.1\|2412077_2412968_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226304
NC_017911.1\|WP_014718070.1\|2424950_2425943_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226324
NC_017911.1\|WP_014718066.1\|2414151_2415180_+\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
NC_017911.1\|WP_014718072.1\|2427550_2428414_+\|SMP-30/gluconolactonase/LRE-family-protein	unknown	unknown	gnl\|CDD\|369882
NC_017911.1\|WP_003190551.1\|2420912_2421635_-\|FadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225097
NC_017911.1\|WP_014718067.1\|2415580_2416672_+\|NADH:flavin-oxidoreductase/NADH-oxidase	unknown	unknown	gnl\|CDD\|239242
NC_017911.1\|WP_003190554.1\|2423611_2424934_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NC_017911.1\|WP_074059269.1\|2419370_2420672_+\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NC_017911.1\|WP_014718063.1\|2407391_2409800_-\|glucose/quinate/shikimate-family-membrane-bound-PQQ-dependent-dehydrogenase	unknown	unknown	gnl\|CDD\|274418
NC_017911.1\|WP_014718061.1\|2404899_2406075_+\|XylR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380485

Protein	Function_ID	Function_description	E-value
NC_017911.1\|WP_014718073.1\|2428453_2429440_+\|substrate-binding-domain-containing-protein	gnl\|CDD\|380482	cd01540, PBP1_arabinose_binding, periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily. Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily. ABP is only involved in transport contrary to other related sugar-binding proteins such as the glucose/galactose-binding protein (GGBP) and the ribose-binding protein (RBP), both of which are involved in chemotaxis as well as transport. The periplasmic ABP consists of two alpha/beta globular domains connected by a three-stranded hinge, a Venus flytrap-like domain, which undergoes a transition from an open to a closed conformational state upon ligand binding. Moreover, ABP is homologous to the ligand-binding domain of eukaryotic receptors such as metabotropic glutamate receptor (mGluR) and DNA-binding transcriptional repressors such as LacI and GalR.	1.09793e-110
NC_017911.1\|WP_003190545.1\|2415190_2415490_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|378968	pfam12840, HTH_20, Helix-turn-helix domain. This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.	2.67048e-12
NC_017911.1\|WP_003190551.1\|2420912_2421635_-\|FadR-family-transcriptional-regulator	gnl\|CDD\|225097	COG2186, FadR, Transcriptional regulators [Transcription].	4.06414e-53
NC_017911.1\|WP_014718064.1\|2409995_2411939_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.97857e-70
NC_017911.1\|WP_014718069.1\|2421683_2423420_-\|dihydroxy-acid-dehydratase	gnl\|CDD\|235708	PRK06131, PRK06131, dihydroxy-acid dehydratase; Validated.	0
NC_017911.1\|WP_014718071.1\|2425953_2427534_+\|aldehyde-dehydrogenase-(NADP(+))	gnl\|CDD\|143447	cd07129, ALDH_KGSADH, Alpha-Ketoglutaric Semialdehyde Dehydrogenase. Alpha-Ketoglutaric Semialdehyde (KGSA) Dehydrogenase (KGSADH, EC 1.2.1.26) catalyzes the NAD(P)+-dependent conversion of KGSA to alpha-ketoglutarate. This CD contains such sequences as those seen in Azospirillum brasilense, KGSADH-II (D-glucarate/D-galactarate-inducible) and KGSADH-III (hydroxy-L-proline-inducible). Both show similar high substrate specificity for KGSA and different coenzyme specificity; KGSADH-II is NAD+-dependent and KGSADH-III is NADP+-dependent. Also included in this CD is the NADP(+)-dependent aldehyde dehydrogenase from Vibrio harveyi which catalyzes the oxidation of long-chain aliphatic aldehydes to acids.	0
NC_017911.1\|WP_014718074.1\|2429436_2430939_+\|L-arabinose-ABC-transporter-ATP-binding-protein-AraG	gnl\|CDD\|183077	PRK11288, araG, L-arabinose ABC transporter ATP-binding protein AraG.	0
NC_017911.1\|WP_014718062.1\|2406071_2407334_-\|carbohydrate-porin	gnl\|CDD\|335962	pfam04966, OprB, Carbohydrate-selective porin, OprB family.	1.75891e-96
NC_017911.1\|WP_014718068.1\|2416861_2418991_+\|TonB-dependent-siderophore-receptor	gnl\|CDD\|236643	PRK10044, PRK10044, ferrichrome outer membrane transporter; Provisional.	1.03449e-100
NC_017911.1\|WP_014718075.1\|2430948_2431917_+\|L-arabinose-ABC-transporter-permease-AraH	gnl\|CDD\|183076	PRK11285, araH, L-arabinose transporter permease protein; Provisional.	9.83587e-172
NC_017911.1\|WP_014718063.1\|2407391_2409800_-\|glucose/quinate/shikimate-family-membrane-bound-PQQ-dependent-dehydrogenase	gnl\|CDD\|274418	TIGR03074, PQQ_membr_DH, membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family. This protein family has a phylogenetic distribution very similar to that coenzyme PQQ biosynthesis enzymes, as shown by partial phylogenetic profiling. Members of this family have several predicted transmembrane helices in the N-terminal region, and include the quinoprotein glucose dehydrogenase (EC 1.1.5.2) of Escherichia coli and the quinate/shikimate dehydrogenase of Acinetobacter sp. ADP1 (EC 1.1.99.25). Sequences closely related except for the absense of the N-terminal hydrophobic region, scoring in the gray zone between the trusted and noise cutoffs, include PQQ-dependent glycerol (EC 1.1.99.22) and and other polyol (sugar alcohol) dehydrogenases.	0
NC_017911.1\|WP_014718070.1\|2424950_2425943_+\|hypothetical-protein	gnl\|CDD\|226324	COG3802, GguC, Uncharacterized protein conserved in bacteria [Function unknown].	0
NC_017911.1\|WP_014718066.1\|2414151_2415180_+\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.69457e-41
NC_017911.1\|WP_014718072.1\|2427550_2428414_+\|SMP-30/gluconolactonase/LRE-family-protein	gnl\|CDD\|369882	pfam08450, SGL, SMP-30/Gluconolaconase/LRE-like region. This family describes a region that is found in proteins expressed by a variety of eukaryotic and prokaryotic species. These proteins include various enzymes, such as senescence marker protein 30 (SMP-30), gluconolactonase and luciferin-regenerating enzyme (LRE). SMP-30 is known to hydrolyze diisopropyl phosphorofluoridate in the liver, and has been noted as having sequence similarity, in the region described in this family, with PON1 and LRE.	5.19739e-81
NC_017911.1\|WP_014718067.1\|2415580_2416672_+\|NADH:flavin-oxidoreductase/NADH-oxidase	gnl\|CDD\|239242	cd02932, OYE_YqiM_FMN, Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis. Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing agent. The YqjM enzyme exists as a homotetramer that is assembled as a dimer of catalytically dependent dimers, while other OYE members exist only as monomers or dimers. Moreover, the protein displays a shared active site architecture where an arginine finger at the COOH terminus of one monomer extends into the active site of the adjacent monomer and is directly involved in substrate recognition. Another remarkable difference in the binding of the ligand in YqjM is represented by the contribution of the NH2-terminal tyrosine instead of a COOH-terminal tyrosine in OYE and its homologs.	0
NC_017911.1\|WP_003190554.1\|2423611_2424934_+\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.57788e-98
NC_017911.1\|WP_074059269.1\|2419370_2420672_+\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	3.83426e-07
NC_017911.1\|WP_003190542.1\|2412077_2412968_-\|hypothetical-protein	gnl\|CDD\|226304	COG3781, COG3781, Predicted membrane protein [Function unknown].	1.08119e-62
NC_017911.1\|WP_014718061.1\|2404899_2406075_+\|XylR-family-transcriptional-regulator	gnl\|CDD\|380485	cd01543, PBP1_XylR, ligand-binding domain of DNA transcription repressor specific for xylose (XylR). Ligand-binding domain of DNA transcription repressor specific for xylose (XylR), a member of the LacI-GalR family of bacterial transcription regulators. The ligand-binding domain of XylR is structurally homologous to the periplasmic sugar-binding domain of ABC-type transporters and both domains contain the type 1 periplasmic binding protein-like fold. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the type 1 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	2.11034e-94

>NC_017911.1|WP_014718068.1|2416861_2418991_+|TonB-dependent-siderophore-receptor
MRRTLISICVLQAFSPFAWAEQAPAENASIELQATNVTATADLESAQGPVQGYHATRSASATRTDTAIHETPQSISVVPKDVVEDLGATRLQDALDYAGGVGRANNFGGQGLTTFTVRGFTTGEFYRNGFPINRGYPNMPDANTIERLEVLRGPATMLYGRGDPGGTFNVVSKQPLAERTVTLGSQLNDQGMKRSTLDASGPLDEEGRLAYRLNVVGEGGDTFRDHVETERYGVTPVITWQATDDTKMTFEGDFMRNNHPLDRGLTRFPNQRGTPSRDTFWGDKDAGKLHNDNNMAQLRFEHVLNDNWTLGGGFQWLDGSLKGNAIEANGPGSLGADGRTLQRNFNYRKLEWTDKDYQLNLTGHFSTGGFDHTLLTGIEYEDYDYKSIIQRSSAAAGTYPIDIFDPVYGQTRPALTRTPTHDKENLKTYAAFVQDQVALTERLKVLAGARFERFEHDYQNYVGKSWQAADNAVTPRVGVIYDLTDTVAVYADAARSFKPNTGASREGGGFAPEKGKSYEMGIKWEALDRQLSVDAAIYQIEKKNVLTTDPVDNTFSVAAGQVRSRGFDLNVAGNLTPEWRVIGGYAYVDAEVTRDNTLRSGTRLMNIPRNSFSLLNVYEFQDGALKGLGLGAGGKYVDQRAGQTANTAFSMDAYTVVDLLGYYKVNERVRLNLDVKNLFNREYEEGAFGNIYAYPGAPRTVQVGIAYTL
>NC_017911.1|WP_014718067.1|2415580_2416672_+|NADH:flavin-oxidoreductase/NADH-oxidase
MSALFEPFKLKDVTLRNRIAIPPMCQYMAEDGMVNDWHHVHLAGMARGGAGLLVVEATAVAPEGRITPGCAGIWSDAHAQAFVPMVKAIKAAGSVPGIQIAHAGRKASANRPWEGDDHIPASDARSWETIAPSAIAFGANLPNVPRAMTLEDIARVQQDFVDAARRARDAGFEWIELHFAHGYLGQSFFSEHSNQRTDAYGGSFDNRSRFLLETLAAVREVWPENLPLTARFGVIEYDGRDEQTLTESIELARRFKDGGLDLLSVSVGFTIPDTNIPWGPAFMGPIAERVRREAGIPVTSAWGFGTPQLAQGALQAGHLDLVSVGRAHLADPHWAYFAAKELGVDKSSWTLPAPYAHWLERYR
>NC_017911.1|WP_003190545.1|2415190_2415490_-|helix-turn-helix-transcriptional-regulator
MRAFKHPTPQELTLERVLYALSDPVRLDIVRYLANVPEATCGELDGGRPKSSMSHHFRVLRDAGLVHTRNVGTTHMNSLRRDELESRFPGLLASVLSQH
>NC_017911.1|WP_014718066.1|2414151_2415180_+|GGDEF-domain-containing-protein
MPANLKLRPRMRSLLSPAVTQAEWVGIIAWVGMLLIPAALKLDFYMLAVTVGLLIVCRVHATTTNFLLWRVLGVTYMVLLSVGFAYLIHMHAELRIYGLPLAVTLVVGSAILFISVQDYLADALLIWLILWPPMQADIYAGTEVYLLLFCAASVSIGFILSYSYLKNLRSVLLVESEFRALAETDYLTSILNRRAFMQSFEKLLGGERGGYFIMLDIDSFKEKNDLYGHDVGDKILRAMALCLKNAKGSHSFGRIGGEEFGVLLQGDDVEVACDYALDLLQAIRSSVPAPHHYTCSAGMARFSPGDELSAVLKMADKNLYGAKRNGKDCVHLDGALLQAVLS
>NC_017911.1|WP_172832686.1|2413297_2414149_+|hypothetical-protein
MRVSSLKLAMCNTAQALERHKDFESCMRAHYHVLLVPYSKRPFFYKSALKYSRLMVSFALLSQYFSTPLPLLAEVKALCVTRKYCSKNSLESIFLLFRALGFMEVAPHPEDSRFRVYAPSDEACREARLMLTALTESLALLYPEREVFRQMRDLDDREFLALYFKGFAMILAAELTVDVLLPECYWLVKRDAGHLLMLAIYNDAFAPENDRATFRSSSYLALAKQLSVSKTHIIRMVQEGVEKGYFKAHSKTRLEVLPPFASLVKRFMAFSFAMGLHAIEMGA
>NC_017911.1|WP_003190542.1|2412077_2412968_-|hypothetical-protein
MKAALLKKYRLIIKTMGYVGWALFWLLLWDVAVTVDFMLFLTAKINLPLMPLTLLGSALVVLISFRNSSAYNRWWEARTLWGAMVNNSRSFARQVLTLLDDAPGEVNPVKSTLLRRHVAYVNCLAAHLKGQPCPEEVRAFIPAEEFARNGATNNFANDILTGSASLLAREYQAGRLDSIRLARLESTLVDLSNAQGGMERIANTPLPYPYVYFPRLFISLFCLIVPVGLVESLGWFTPLASTVVGFMLLAIERIGTDLQSPFNSSEHQIQMESICETIEKNLQSMRRDALVGDPIA
>NC_017911.1|WP_014718064.1|2409995_2411939_-|methyl-accepting-chemotaxis-protein
MNIKQKLTWAFAAIACVPVILVAIIVVLNLREGALANFLDSSGREIRQIDNGMQQFFDGISQNVDFVAKDPRVIAAKNLKSYAGADAAQIPLTPTNTELLAIFDQFAKSHPSTAYLSLGLSDGGYASWPDDAKLTQYDPRTRPWYQAAIAAPGKTVRTGAYYWAPDDVVLIGTVRTVADATGNVLGVVGLDVSLKQLTELVRTIKLGDSGYLMLVEADGNVLVDPSDATHNFKPLAGLGANYAELAKHGDGVTEVSIDGVAYMANVVSSKDLGWRFIGLIKRDEVMAGATRLTWLIAAIAAVLAVVFAIVGASFARVIVRPIRGVADGLQEIAEGEGDLTRQLKVQGKDETASLAGWFNQFLSMIAQLVQRIGNASSDLQTAAADTSAVANNMNQAAGRQREAVELVSTAFNEMVATANEVARSCSAAATSADEGYRDVHTGQQHIGEATGSVLKLSEDLQKSTQTMQLLEQDSQNINTILDTIRSIAEQTNLLALNAAIEAARAGDQGRGFAVVADEVRALARRTADSTGEIDSLLGNLARRTQEVTQQMQGSLLVSNTSVERIQQARDSFDKIRGSVDSIRDQNTQIATAAEEQHQVAEEINRHIAQIHADAQLVEGFAHSAQTGSGRLTDISGQLNGLVGRFKF
>NC_017911.1|WP_014718063.1|2407391_2409800_-|glucose/quinate/shikimate-family-membrane-bound-PQQ-dependent-dehydrogenase
MKRASRAAGVSRFLLLGLGVVIVLLGLALAVGGAKLVSLGGSWYFLLGGVAMAISGLLIARCKPAGAWLFAAFLVATAVWAVADVGLEYWPLFSRLFMFAVIGVVVALVYPLLAGKPARGAYGVAAVLALGVAVAAGNMFVAHPSVAPTGAGPGMTPVAAADAQKDWAHYGNTEGGSRFAALDQINRDNIDKLKVAWTYHTGDVAISDGNGAEDQLTPLQVGNKVFICTPHNNLIALDADTGKELWKNEVNAKSAVWQRCRGMAYFDASAPIAQPTQPNSSPILTASVPVGAQCQRRLLTNTIDARLIAVDADTGKFCEDFGTHGQVDLKAGLGNVPDSYYQLSSAPLMAGTTVVVGGRVADNVQTDMPGGVIRGFDVITGQMRWAFDPGNPEDKQAPTGDATYVRSTPNSWAPMSYDPLMNTVFLPMGSSSTDIYGVERTQLNHKYGASVLALDASTGAEKWVYQTVHNDLWDFDLPMQPSLIDFTPPGSDKAVPALVIGTKAGQIYVLDRATGKPLTDVQEVPVKAANIPNEPYSLTQPKSVGMPQIGAQTLTESDMWGATPYDQLLCRIDFKGMRYDGLYTAPGTDKSLSFPGSLGGMNWGSISTDPVHGFIFVNDMRLGLWIQMIPSQNKAQASSGGEALNTGMGAVPLKGTPYAVNKNRFLSVAGIPCQAPPFGTLTAIDMKTQKVAWQVPVGTVEDTGPLGIRMHLPIKVGLPTLGGTLSTQGGLIFIAGTQDFYLRAFNSGNGDEIWKARLPVGSQGGPMTYVSPKTGKQYIVVTAGGARQSTDRGDYVIAYALP
>NC_017911.1|WP_014718062.1|2406071_2407334_-|carbohydrate-porin
MTPTPHTAWRLALGLAFAAALPVQADDTTLTGDWGGLRRELDAQGVRFTGDYSGEAAYNAHGGQHRSARYSQNVKLGVQFDLGKLYGFTNGDRIQLTINDRRGNSASEDLVGNRLPIQENYGGLYTRLTELSYERTLFTPALNLKLGYMAMGNDLGGLDSGILCNFMNAGFCGHPLNMSGGGGWANYPNAHLGARLKYDFSPNWQLRVAAFNVDPSSNGNSSRAWHLGPKHTTGTVVPIELIYKHAGALPGEYKLGYYYDSSDVKRIGSNKDVSGRGGHYLLIDQAVWASPSSQGRSLHAFGQYSAASQAASPFTKWYGAGVVLYKPFEGRPRDTVALGYGRAVPNPRSRDVQELAAFNAGTAYPDLDTAEQLIELSYGYQATPWLTLRPDVQYIIEPGAFSGESIDNALVLGLQVKAVF
>NC_017911.1|WP_014718061.1|2404899_2406075_+|XylR-family-transcriptional-regulator
MKTLPPVHRIALLFNGSKIYDRGIIAGIGNYLSSTRASWDLFLEEDFLCRLRGIERWQGDGIIADFDDPLIGEALAGSRLPVVAVGGSYEDVSKYPKGIPYVATDNHALMKLAYEHLVEAGLTRFACFSLPEAQANRWAQEREKAFRRLMQRDGLQVEVYRGLGTSAPLWDSAVEQQIAWLHSLPKPIGIIAVTDARARQLLQACLTAGIAVPEEVALIGIDNDPLTRTLTRVPLSSVIQGTETMGRTAAALLHQMLHGKPCTGTQVLVPPDAINVQASSLHQPLGNPYVMQALLFIRQYACQGIKTDQVAAYVGVSRSSLEAHFRKARGCSVHDEILRFKLTAAAKGLENHSLAIADIAARCGFTSAQYLHTVFRREFGCTPRQYQQGTN
>NC_017911.1|WP_074059269.1|2419370_2420672_+|IS4-family-transposase
MAKLALQQAIAPEWIDQVFEEHRQRQYSRELLFSTIIKLMSLVSLGLKPSLHAAARQLEDLPVSLAALYDKISRTEPALLRALITGCAQRLAPTIRELGCTAMLPGWQVRVVDGNHLASTEKRLGALRNERGAARPGFSVVAYDPDLDQVVDLQACEDAYASERVCVLPLLANAEPGQVWLADRLYCTLPVMEACEQVQTCFVIRQQAKHPRLIQEGEWQEPVPVETGTVREQIIQVKGGYQCRRVELTLHSPTDSGDSSLMFWSNLPESVSAQQIAELYRRRWSIEGMFQRLEAILESEIETLGSPKAALLGFATAVLAYNVLAVLKRSVEQAHRDTQPEGWEASIYHLAVQVRSGYEGMQIALPSEHFPVIPLEKLAQHLLALARNIQPKQVAKSPRGPKVPKPKTWVKGTAVNAHVSTDRIIKAAKTKRP
>NC_017911.1|WP_003190551.1|2420912_2421635_-|FadR-family-transcriptional-regulator
MDHQPPKPRKSQHAQIVQDLGMHIVSGRFKPEERLPMEATLCEEYQVSRSVLREATRVLSAKGLVYSKPRVGAVVRPRLKWHLLDPDVLSWLMQSTPHSEFFNTLAGVRRILEPEIAAMAATTATDEDIATIEHAYQGMETAKTHEELLQADLDFHRAIADATRNDLLAYMCNMLSLPLRESINITNRRPDIQGLSLPRHKAILTAIQNRDALGARHASLVQLDDTRVALDTVMNVLTPL
>NC_017911.1|WP_014718069.1|2421683_2423420_-|dihydroxy-acid-dehydratase
MPDKKPGLRSAQWFGTADKNGFMYRSWMKNQGIADHQFHGKPIIGICNTWSELTPCNAHFRQIAEHVKRGVIEAGGFPVEFPVFSNGESNLRPTAMLTRNLASMDVEEAIRGNPIDGVVLLTGCDKTTPALLMGAASCDVPAIVVTGGPMLNGKHKGQDIGSGTVVWQLSEQVKAGTITLDDFLAAEGGMSRSAGTCNTMGTASTMACMAEALGTSLPHNAAIPAVDARRSVLAHMSGMRAVEMVREDLKLSKILTKEAFENAIRVNAAIGGSTNAVIHLKAIAGRIGVELDLDDWTRIGRGMPTIVDLQPSGRFLMEEFYYAGGLPAVLRRLGEANLIPHPNALTVNGKSLGENTQDSPIYGQDEVIRTLDNPIRADGGICVLRGNLAPLGAVLKPSAASPELMQHRGRAVVFENFDMYKARINDPELDVDANSILVMKNCGPKGYPGMAEVGNMGLPAKLLAQGVTDMVRISDARMSGTAYGTVVLHVAPEAAAGGPLATVKEGDWIELDCANGRLHLDIPDAELAARMADLPPAQNLIVGGYRQLYIDHVLQADQGCDFDFLVGCRGAEVPRHSH
>NC_017911.1|WP_003190554.1|2423611_2424934_+|MFS-transporter
MSQELRLIRRITLKLIPFLILLYLIAYVDRSAVGFAKLHMGADVGIGDAAYGLGAGLFFIGYFLFEIPSNLMLDRFGARRWFARIMITWGAITIGMAFVQGPHSFYVMRFLLGAAEAGFFPGVLYYITQWFPVRHRGKILGLFILSQPIAMMITGPVSGGLLGMDGILGLHGWQWLFIVIGTPAILLTWPVLRYLPDGPQKVNWMSEEEKAWLTGELHKDLQAYGQTRHGNPLHALKDKRVLLLALFYLPVTLSIYGLGLWLPTLIKQFGGSDLTTGFISAVPYIFGIIGLLIIPRSSDRLNDRYGHLAVLYVLGAIGLFCSAWLTVPVLQMAALCLAAFAMFSCTAVFWTLPGRFFAGASAAAGIALINSVGNLGGYIGPFVIGALKEYTGNLASGLYFLSGVMVFGLLLTLVVYRLLERKHVLPVDQFAASARGATRT
>NC_017911.1|WP_014718070.1|2424950_2425943_+|hypothetical-protein
MRLVQFELSNGERRVGVVEGNQVREVRGAHSVRELALAAIEAGGKLQQQVQALGLGASHDYTALLADHKILPPLDHPDPAHMLISGTGLTHLGSASARDKMHQQAGDDSAMTDTMRIFKWGVEGGKPGAGQAGVQPEWFYKGDGSIVVRPGQAFPVPPFAEDAGEEPEIGGLYVIGHDRKPYRLGFAVGNEFSDHVMERKNYLYLAHSKLRSCSYGPELRVGELPEHLAGTSRILRNGEVIWQNEFLSGEANMCHSLENLEYHHFKYSQFLKPGDVHIHFFGTATLSFADGIRTQPGDVFEISQAEFGAPLINGIGSSDAAFEPGQVTPL
>NC_017911.1|WP_014718071.1|2425953_2427534_+|aldehyde-dehydrogenase-(NADP(+))
MTPFLGHNYIGGQRSANGSIKLQSIDATTGEALPQDFYQATAQEVDAAAQAAAQAYPAYRALSAARRAQFLDAVADELDALGDDFVELVCRETALPAARIKGERGRTSGQMRLFATVLRRGDFYGARIDKALPERQPLPRPDLRQYRIGLGPVAVFGASNFPLAFSTAGGDTAAALAAGCPVVFKAHSGHMATAERVADAIIRAAEATEMPAGVFNMIFGGGVGEALVKHPAIQAVGFTGSLKGGRALCDMAAARPQPIPVFAEMSSINPVIVLPQALHARAESIARDLTASVVQGCGQFCTNPGLVIGIASPAFTAFTQQVAQLIGEQPAQTMLNAGTLGSYGKGLEKLRSHPGIQHLAGSAQSGNQAQPQLFKADVRLLIDGDEVLQEEVFGPTTVFVEVADQAQLSAALQGLHGQLTATLIGEPADLQQFAELTPLLEQKVGRILLNGYPTGVEVCDSMVHGGPYPATSDARGTSVGTLAIDRFLRPVCFQNYPDSLLPDALKNANPLRIQRLVNGTPSRESL
>NC_017911.1|WP_014718072.1|2427550_2428414_+|SMP-30/gluconolactonase/LRE-family-protein
MSLSAVTPHRARLGEGPFWDVPTQALYWVDIAARQALRLMGGQLQVWQLPEHVSAFIPCQRGDALVTLSSGVYRLDLATEALTLLCVADPQTGNRGNEARCDAQGRLWLGTMQNNIGEQGEDLPITRRSGGLFRIDADARVTPLLAGLGIPNTLLWNEEGSQVHFGDSMDGTLYQHSIQADGQLGAAQAWFGPHTRGGPDGSAMDADGYIWNARWDGSCLLRLTPSGEVDRIIELPVSRPTSCVFGGPELTTLYITSAASPLDHPLDGAVLAIEVDVPGKPCHRFAG
>NC_017911.1|WP_014718073.1|2428453_2429440_+|substrate-binding-domain-containing-protein
MKKVLRVLAAAVALSSLSSIVSAEDVKIGFLVKQAEEPWFQTEWAFAEKAAQDKGFKLIKIAVPDGEKTLSAIDSLAANGAKGFVICPPDVSLGPAIVAKAKVNGLKVMAVDDRFVDAKGNFMEDVPYLGMAAFEVGQKQGAAMAAEAKKRGWDWKETYAVINTFNELDTGKKRTDGSIKSLEEAGIPKDHILTAALKTLDVPGSMDATNSALVKLPSGAKNLIIGGMNDNTVLGGVRATESAGFAAANVIGIGINGTDAIGELKKANSGFFGSMLPSPHIEGYKTAEMMYEWVTQGTEPPKYTAMDEVTLITRENFQAELTKIGLWK
>NC_017911.1|WP_014718074.1|2429436_2430939_+|L-arabinose-ABC-transporter-ATP-binding-protein-AraG
MTAAALRFDGIGKTFPGVKALDGICFTAHPGQVHALMGENGAGKSTLLKILGGAYIPSSGTVQIGAQTMAFKCAADSIASGVAVIHQELHLVPEMSVAENLFLGHLPTRFGVVNRGLLRKQALACLKGLADEIDPDEKLGRLSLGQRQLVEIAKALSRGANVIAFDEPTSSLSAREIDRLMAIITRLRDEGKVVLYVSHRMEEVFRICDAVTVFKDGRYVRTFEDMSTLTHDQLVTCMVGRDIQDIYDYRPREQGEVALKVDGLLGPGLREPISFQVRKGEILGLFGLVGAGRTELFRLLSGLERASAGSLELCGQALQLRSPRDAIAAGVLLCPEDRKKEGIIPLGSVAENINISARGAHSTFGWLLREGWEKGNADRQIQAMRVKTPNAAQKILYLSGGNQQKAILGRWLSMPMKVLLLDEPTRGIDIGAKSEIYQIIHNLAASGIAVIVVSSDLMEVMGISDRILVLCEGALRGEQLREHATESNLLQLALPRGLAN
>NC_017911.1|WP_014718075.1|2430948_2431917_+|L-arabinose-ABC-transporter-permease-AraH
MTIQNNALPSARKPLDMRALLDNWAMLLAAVGIFVLCALLIDNFLSPLNMRGLGLAISTVGIAACTMLFCLASGHFDLSVGSVIACAGVVAAIVMRDTDSVMLGIGAALLMGLMVGLINGIVIAKLRVNALITTLATMQIVRGLAYIFADGKAVGVSQEQFFVFGNGQLFGVPVPILITIVCFLFFGWLLNYTTYGRNTMAIGGNPEAALLAGVNVDRTKILIFAIHGLIGALAGVILASRMTSGQPMIGQGFELTVISACVLGGVSLSGGIGMIRHVIAGVLILAIIENAMNLKNIDTFYQYVIRGSILLLAVVIDRMKQR

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Crispr_ID: NC_017911_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017911_6

2484217-2484321

Orphan

Consensus_repeat	Method
TGTGGGAGCTGGCTTGCCTGCGATGGCGGCCTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017911_6

>merge|NC_017911|6|2484217-2484321|CRISPRCasFinder
TGTGGGAGCTGGCTTGCCTGCGATGGCGGCCTGCCAGCCGACACCTATCTACCTGACGCCCCGCGATCAATTTGTGGGAGCTGGCTTGCCTGCGAAGGCGGCCTG

>NC_017911|6|5|2484217-2484321|CRISPRCasFinder
TGTGGGAGCTGGCTTGCCTGCGATGGCGGCCTG	CCAGCCGACACCTATCTACCTGACGCCCCGCGATCAATT
TGTGGGAGCTGGCTTGCCTGCGAAGGCGGCCTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017911.1\|WP_144269781.1\|2491998_2496711_-\|RHS-domain-containing-protein	unknown	unknown	gnl\|CDD\|225750
NC_017911.1\|WP_014718112.1\|2483690_2484161_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NC_017911.1\|WP_014718107.1\|2467067_2467622_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|183232
NC_017911.1\|WP_014718103.1\|2463394_2464714_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340925
NC_017911.1\|WP_014718115.1\|2486243_2486426_+\|rubredoxin	unknown	unknown	gnl\|CDD\|224687
NC_017911.1\|WP_014718106.1\|2466223_2466940_+\|dienelactone-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223477
NC_017911.1\|WP_014718108.1\|2467694_2469506_-\|cation:proton-antiporter	unknown	unknown	gnl\|CDD\|235131
NC_017911.1\|WP_014718116.1\|2486453_2487323_+\|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl\|CDD\|224007
NC_017911.1\|WP_014718121.1\|2491690_2492002_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376019
NC_017911.1\|WP_014718105.1\|2465457_2466213_+\|precorrin-6A-synthase-(deacetylating)	unknown	unknown	gnl\|CDD\|236218
NC_017911.1\|WP_014718111.1\|2482322_2483567_-\|methionine-gamma-lyase	unknown	unknown	gnl\|CDD\|181005
NC_017911.1\|WP_014718104.1\|2464857_2465412_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366010
NC_017911.1\|WP_080643481.1\|2491355_2491640_-\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_014718114.1\|2484654_2486085_-\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NC_017911.1\|WP_014718120.1\|2490945_2491362_-\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_014718118.1\|2488104_2489163_+\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|182329
NC_017911.1\|WP_014718119.1\|2489211_2490441_+\|M20/M25/M40-family-metallo-hydrolase	unknown	unknown	gnl\|CDD\|235710
NC_017911.1\|WP_014718117.1\|2487392_2488025_+\|LysE-family-translocator	unknown	unknown	gnl\|CDD\|224199
NC_017911.1\|WP_014718110.1\|2481421_2482093_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197715
NC_017911.1\|WP_014718109.1\|2469917_2481305_+\|autotransporter-associated-beta-strand-repeat-containing-protein	unknown	unknown	gnl\|CDD\|226973

Protein	Function_ID	Function_description	E-value
NC_017911.1\|WP_014718112.1\|2483690_2484161_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	2.35456e-47
NC_017911.1\|WP_014718107.1\|2467067_2467622_-\|hypothetical-protein	gnl\|CDD\|183232	PRK11615, PRK11615, hypothetical protein; Provisional.	1.97106e-08
NC_017911.1\|WP_014718103.1\|2463394_2464714_+\|MFS-transporter	gnl\|CDD\|340925	cd17367, MFS_KgtP, Alpha-ketoglutarate permease of the Major Facilitator Superfamily of transporters. This subfamily includes Escherichia coli alpha-ketoglutarate permease (KgtP) and similar proteins. KgtP is a constitutively expressed proton symporter that functions in the uptake of alpha-ketoglutarate across the boundary membrane. Also included is a putative transporter from Pseudomonas aeruginosa named dicarboxylic acid transporter PcaT. The KgtP subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.62583e-121
NC_017911.1\|WP_014718115.1\|2486243_2486426_+\|rubredoxin	gnl\|CDD\|224687	COG1773, COG1773, Rubredoxin [Energy production and conversion].	8.42438e-18
NC_017911.1\|WP_014718106.1\|2466223_2466940_+\|dienelactone-hydrolase-family-protein	gnl\|CDD\|223477	COG0400, COG0400, Predicted esterase [General function prediction only].	1.72113e-37
NC_017911.1\|WP_014718108.1\|2467694_2469506_-\|cation:proton-antiporter	gnl\|CDD\|235131	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional.	0
NC_017911.1\|WP_014718116.1\|2486453_2487323_+\|sugar-phosphate-isomerase/epimerase	gnl\|CDD\|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	6.27822e-20
NC_017911.1\|WP_014718121.1\|2491690_2492002_-\|hypothetical-protein	gnl\|CDD\|376019	pfam18593, CdiI_2, CdiI immunity protein. Contact-dependent growth inhibition (CDI) is an important mechanism of inter-bacterial competition found in many Gram-negative pathogens. CDI+ cells express cell-surface CdiA proteins that bind neighboring bacteria and deliver C-terminal toxin domains (CdiA-CT) to inhibit target-cell growth. CDI+ bacteria also produce CdiI immunity proteins, which specifically neutralize cognate CdiA-CT toxins to prevent self-inhibition. Structure analysis of CdiI immunity protein from Yersinia kristensenii shows that it is composed of eight alpha-helices packed together to form a nearly spherical structure with weak structural homology to a putative TetR family transcriptional repressor. The CdiI protein fits into the curved cavity of the CdiA-CTYkris toxin domain where it most likely neutralizes toxin activity by blocking access to RNA substrates. This domain is mostly found in gammaproteobacteria.	3.31849e-14
NC_017911.1\|WP_014718105.1\|2465457_2466213_+\|precorrin-6A-synthase-(deacetylating)	gnl\|CDD\|236218	PRK08284, PRK08284, precorrin 6A synthase; Provisional.	9.41431e-155
NC_017911.1\|WP_014718111.1\|2482322_2483567_-\|methionine-gamma-lyase	gnl\|CDD\|181005	PRK07503, PRK07503, methionine gamma-lyase; Provisional.	0
NC_017911.1\|WP_014718104.1\|2464857_2465412_+\|histidine-phosphatase-family-protein	gnl\|CDD\|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	1.85965e-17
NC_017911.1\|WP_144269781.1\|2491998_2496711_-\|RHS-domain-containing-protein	gnl\|CDD\|225750	COG3209, RhsA, Rhs family protein [Cell envelope biogenesis, outer membrane].	4.54282e-45
NC_017911.1\|WP_014718114.1\|2484654_2486085_-\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	5.37337e-110
NC_017911.1\|WP_014718118.1\|2488104_2489163_+\|diguanylate-cyclase	gnl\|CDD\|182329	PRK10245, adrA, diguanylate cyclase AdrA; Provisional.	2.94168e-80
NC_017911.1\|WP_014718119.1\|2489211_2490441_+\|M20/M25/M40-family-metallo-hydrolase	gnl\|CDD\|235710	PRK06133, PRK06133, glutamate carboxypeptidase; Reviewed.	0
NC_017911.1\|WP_014718117.1\|2487392_2488025_+\|LysE-family-translocator	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	3.57788e-32
NC_017911.1\|WP_014718110.1\|2481421_2482093_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	4.24962e-08
NC_017911.1\|WP_014718109.1\|2469917_2481305_+\|autotransporter-associated-beta-strand-repeat-containing-protein	gnl\|CDD\|226973	COG4625, COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain [Function unknown].	7.3947e-46

>NC_017911.1|WP_014718112.1|2483690_2484161_+|Lrp/AsnC-family-transcriptional-regulator
MPIKLDRTDKALLNALQGNARLTVAELAERVALTTSPCWRRVRTLEESGVISGYQAILSPKALGYGVTAFVSIMMESHTQEIARAFEQRLLAIPEIVACHNVSGRYDFLLEVVAKDLESFGEFAREVLQTLPCVKEIYSSFSYKSVRPLRVIPLPG
>NC_017911.1|WP_014718111.1|2482322_2483567_-|methionine-gamma-lyase
MHTQHTSFGFCTRAIHHGYDPVDHHGALVPPIYLSATFAFPTVEYGAACFAGEASGHFYTRISNPTLALLESRMASLENGEAAVAFSSGMGAIAATFWTLLRPGDEIIVSQTLYGCTFALLHHGLGEFGIKVRHVDLTDLAALQAAFSPATRMLYCETPANPNLRLIDIAAVAELAHQQPNVTVVVDNTYCTPYLQRPLELGADVVVHSATKYLSGHGDITAGVAVSHQALAQRIRLQGLKDLTGAVMSPQDASLLMRGLKTLALRMDRHCSNAQALAEALQAHPAVESVIYPGLRSFPQYELATRQMKLPGGMIAFELKGGIETGRRFMNALQLFTRAVSLGDAESLAQHPASMTHSTYTPEQLAQHGISEGLVRLSVGLEDVADLLTDIQQALAKCSGANLRPAPTAVYAMK
>NC_017911.1|WP_014718110.1|2481421_2482093_-|helix-turn-helix-transcriptional-regulator
MNSHLFPQIGKVIASTGSRHFPRMLHDLILSQLAVDATHITQLHVSREGLGRRKISPVYTDSVAALGSEQLAAQLHLTGRKDDVRYVLSVYRSHPSDSFSAQERSMLQDFSALLLPMVEKHITALQPSLPDSPCAVPQHQGIDTLHRRIQERLVQSGLTLSNRELQVCVGLLAGRTAPELAEQLALKVNTIESYLKRAAIKLGISGRHSLLRWMYSTEDGTRF
>NC_017911.1|WP_014718109.1|2469917_2481305_+|autotransporter-associated-beta-strand-repeat-containing-protein
MDRRLATAALPRISALSLAIRLGVAGLVMGLASPDVFAACSPASPTAGATVTCTGVPTLPLFLNTFSSAVNSLTVNVNAGAQLNATLGGKALTLTGNNTTLNNSGTIDPALLGLVSVLSGGVVIGNTAASALNITNSASGIMRGTGALLGLNLASLDGMALNATNGAGGTTTIVNNGVIGSSSLLGLSLLTSDTPVVAVQGGGQVNMTNNGTLTGRVAFESSTTGNTFRNTGTISGGVSMGAASTNTFTAVTGSQVTNGGGLGLSLGGLIGVNLTFAPTGQVDGGAGGSNSLILENTTGVGGGSTGTGTASSANYVNFNNLAINSGTWTLQGPLVSGSTTLNGGVAQFNNNATFGSGVLTSNGGAIEAAGNGLTLANLMTLGTGGLTVQGASTGLTLSGVISGAAGVGKAGTGELILSGTNTFQGGTTLNAGTLTLGNAAALGSGALTVAGAGTLQSNAALTTSNAITLNANLTVDGVNPLTLGGVVSGGSGLIKEGVSSLALTGNNTYTGATALNAGSLVVGSNTALGASALNASAGTTLDASAAVSLGNNLNLGGNLTLGGSSALTLGGVVAGLGGLIKNGPADLLLNQANTYLGNTALNSGKLVIGATGALGAGTLNAAAGTTLDASTSATLTNAINLAGNLGIGGSANLTLGGTVNGAGSLTKNGTAGLTLSGSNNFLGGTTLNAGTLTVGSNTALGLGNLTVGGAATLDSTSAVALGNGIALNAGLTVGGTNGLTLGGVVSGAGALIKDGLANLTLNGTNTFTGGTSLNAGTLTLGTAGALGAGPLTVGGAATLDTSATFTLGNGIALNGDLTLAGNNDLNLSGVLSGASALIKNGLADLTLSGTNTFTGPLNIVSGSVTTGSTGALGNTSGVNVSTGAALNLGVDSSLAGLSGAGGVAVSGGLNLTVGGVNTSSTFDGDLSGAGSLIKVGTGTLTLNGINGITGNTAINAGTLDVDGSLGSASVNVNTGGTLTGSGSLLGTANINNGGHLALGSGTTLSAAGLNMSAGASLDVALGAPSLTSLMNVGGNVNLAGDLNVSDAGGFGAGVYRLINYTGGLTGALNVNTVPLGYGLGDLLVQTSVGSQVNLVVAAPNIRFWDGSNTLANGTVDGGNGTWTAGGTNWTSADGLSNQTWGGGFAVFQGAAGTVSVDGVQTITGLQFVTDGYSLVNGTGGQLSTGSGNFAVRVDPLATATLGVDITGAGVLNKLDTGTLVLNGANSYTGGTLLNGGTVVVGSNTALGTGTLTAAAGTTLDSNTSVTLGNDAVLNGSLTVGGSNALALNGAISGTGGLVKNGTAGLTLGGTNTFLGPVALNAGGLILASNTALGAGVLNAAGGTTLDASTAVTTTNAINLAGNLGIGGTADLTLGGAINGAGSLTKEGTANLILSGANAYLGGTTLNAGTLTLGSATALGLGNLTVGGAATLDNTAALSVGNGVVLDANLAVTGSNDLTLGGLVTGTAGLSKDGAANLTLNGVNTFQGGTSLNAGTLTLGTAAALGTGALNVNGAATLANSTPLVLANAVNLNAGLTVGGLNNNLTLAGVLAGSGSLVKTGTADVSLTGTNTFNGLFDVQSGSLTTLGNGALGVGAGVNLASGTALNLGGSASLGALTGTGLATVGAGSTLSVGNNNLDSTFNGVVAGLGNLAKDGTGALTLGGLSVVTGDAQVNAGSLLVNGSLASANVAVGSGATLGGTGTLLGNVSIADGGHLAVNSGATLTTGSLLLNANANLDAGLGAPATGGTALVQVNGNLTLDGTLNVTDIGGFGAGIYRLIDYTGGLTNNGLLLGSLPVNIPASDLDLQTAIGNQINLLVNGSTNVQFWDGSQTTGNGTIEGGSGTWSAGGSQWTGVNGAFNTAWTPNSFAVFQGTAGTVTVDGAQAITGLQFVTDGYNLAGGAAGALTLFNGVGGNTAVRVDPGVTATLGVALNGGGTLAKLDTGTLVLNGANSYTGGTALDGGTLVVGNNSALGSGLLTTANGTTLDSNTAVSLANALNVNGSLTLGGSNALTLAGTVAGTGSLIKNGIANLTLSGNNTYAGPTALNAGGLILASNSALGSGALNAAAGTTLDSSTAVALANTVNLAGNLGILGTADLSLNGLVSGTGGLIKTGVSNLTLNGANAYLGGTQLNAGSLTLGNASALGSGALAVNGATTLDTNTALAVANNTSLNAALTIGGSNDLSLNGVVDGSGSLTKAGGANLTLNGTNTYSGGTALNAGTLTVGSTTALGSGALTVGGTATLANSTPLVLANAVNLNGDLTVAGSNNLTLAGVLAGNAALIKNGAADLLLTGNNSFSGPLTVAAGSVTTTGNGALGTTSSVTVGSGASLNLGGNANLNSLAGNGVVQVAGGNTLAVGGSNLDNSFGGALNGAGNLDKNGSGVLNLSGTNAISGAANVNGGTLNVTGSLASGTVAVNSGATLAGSGSLAGAVTVADGGHIGLASGSTLSVGSLVLGGNSNLDVGLGTPVLGGGTGLLNVGGNLTLDGNLNVTDIGGFGSGVYNLINYTGALTDNGLALGTLPGSVVPGDLQVQTAITNKVNLLVTAPNTTVQFWDGNSLIGNGAIDGGNGTWNAGNTNWTNVDGTLNQGWANSFAVFQGEAGNVTVDGTQNITGMQFVTDGYTLGSGTAGVLNLVNGGTGNTAVRVDPNATATLGVTLNGAGTLAKLDSGTLVLNGNNGYTGGTALNGGTLVVGNNSALGTGALTAAGGTTLDSNAAVSLANAAVLNGALAVAGSNALTLDGVVSGSGSLVKNGAAALTLNGVNSYSGGTGLNAGQLILGNNAALGSGALTVGGAAQLDGSTDLQLANTLNLGGALTLAGSHDLALNGVVSGSGGLVKNGNGDLLLTAANTYSGGTTLNGGSTTGNTTSLQGAIANNAALTFEQAIDGTYTGNLTGTGVLNKTGTGALLLSGNNTFTGNTNVNTGSLLVNGTLNSAAVQVASGATLGGSGTLGGAVNMADGSVLQAGAATPLSVGSLALSSGTTLDFALGAPGASSTAVNVAGNLTLDGTLNVSDTGGFGVGVYQLFRYGGSLTDNGLTFGTLPVALGNLSLQTALANQLNLVVQTTPGQIQFWNGGTTNPDGSITGGSGTWGPGTNWTDPTGTQGQASTNQFAVFGGQGGTVTVVGNQGFTGLQVLDAGYTLVAGAGGSLSPTNAADGSLAPVRVNSGVTAQIDAPLVGTGGINKLDAGTLLLTGANTYTGGTTVSGGTLAGTTTSLRGRILNNARLLFTQRTNGQFSGTLSGTGALIKQGAGALLLTGNQPFSGTVAVEEGVLQVGNAANPGAVLGGQVTVANGAGLTGNGSVGSLVNNGSVTPDGGKLTVAGNFTNASTGALNLVITPSTTGSLAVGGTANLGGTLNVVNLAPYAGATTYTLLTAGAVNGTFATTNLENLAFLTTALNYSPTQVALAVSRNDVSYASVAATGNQRGVAAALGTGTAVGGAAVQNALLNGDAGAARAAFDSLSGEIHASTASAMLEDSRYVRDAVNERLRQPGCYREDDPRNALAPSENHLSSAGCHGEMVGWMRVLGTWGHMGGDSNSAKLDRNLSGFLLGTDKQVDDAWRVGVAAGYTRSDLDAKRRNSSADVDSYHLMAYTAYQQEAFAARMGVAYSWHDVESKRNVAVGGEGQRLKADYKARSAQVFGEVGYTIQTPTVALEPFAGLAYVNYDSDTIKEKGGSAALRGDADQDITYSTLGVRIGQTITLGNGSKITPRGSIGWRHAFGDTKPDADLSFINGGGSFSTQGVPIAKDSAVVEAGLDYQISQNGRLGLGYSGQLSRNDKDHAVTVSFSLGF
>NC_017911.1|WP_014718108.1|2467694_2469506_-|cation:proton-antiporter
MPHEGNLLQAAVVFLFAAVLTVPLAKRLQLGAVLGYLFAGVIIGPSVLGLIGNPQSVAQFSELGVVLLLFIIGLELSPKRLWVMRKAVFGVGLAQVLLTGVVMGAVALWLFGQSWNSAIVLGLGLALSSTAFGLQSLAERKELNQPHGRLAFAILLFQDIAAIPLIAMVPLLAGSDHPTTEAQGLQHVLQILGSIAVVIIGGRYLLRPVFRIVAKTGLREVSTATALLVVIGTAWLMELVGVSMALGAFLAGLLLADSEYRHELESQIEPFKGLLLGLFFISVGMGANLSLLLSTPLVVIGLTLLLIGLKLPLLYAVGRMVGDLNRESALRLGVVLAAGGEFAFVVFKIGRDQGLFEPQLYDVLVLTITLSMAVTPLLLLVCPKLFKPKVKPVEVPEEYRAIESDAPRVVIAGMGRMGQIVARILRAQNISFIALDTSVETIELTRSFGGMPVFYGDPQRPEILHAAKVDQAEFFVIAMDDPEINIKTAELVRNLYPHMKIIARARNRQHVHRLVDLDASPVRETFYSSLEMSRRTLVGLGLSQAQADARINRFKTHDQQVLAAQHAVYDDAAKVMQTAQEARGELARLFEMDRLEEESSDKV
>NC_017911.1|WP_014718107.1|2467067_2467622_-|hypothetical-protein
MATFTKTAMLLALALTAGSVFAAAKPTTQTISTLGGKFTFKLPKAYSADTLPSGTAQDGTADTQGTLYANSTTKSVVIVAETVRNDGATIQDNDPQFLDGAVADFVKDQSAALPDFKKLGEKKLTYKGLGLRQVDSSATQGGGKTLNSTFLGGSGNHLLVIQAISRADDVKGHAQLVKQITGGK
>NC_017911.1|WP_014718106.1|2466223_2466940_+|dienelactone-hydrolase-family-protein
MLKQLALALALVAGAAHADTGLHTDLPLSYLEQTQDDARNQPLVIFLHGFGSNEEDLFGIKDALPSTWTYLSVRAPLPVEPQGYRWFTKTDEPEYNGETDELFSSARLIKDFVLKATAKYHTQSDRVFLVGFSQGAIMSYEVALREPEWVRGIAALSGSVLPGLRSALKPDASMGKLAIFIGHGTLDQALPFSSATQANKVLTGLGLKPEFHEYPGMNHTISEAEIQDLKAWLEKSLK
>NC_017911.1|WP_014718105.1|2465457_2466213_+|precorrin-6A-synthase-(deacetylating)
MKRILIIGIGAGNPDYITMQAVKALNRTDVFFLMDKGQSKDKLIDLRREICDTYITEPGYRFVEADCPERVRGEIDYTTAVQDLNRDKQQTFERMINEEMADGEVGAFLAWGDPALYDSTIRILQAILASGRCVFEFEVIPGITSVQTLAAQHKVPLNRIGKSIEITTGRRLAAGQASDADTLVVMLDAEDSYRSVADQDLDIYWGAYLGTPDEILISGKVAQVAEEIERVRKAARLENGWIMDTYLLRKP
>NC_017911.1|WP_014718104.1|2464857_2465412_+|histidine-phosphatase-family-protein
MPATRLTLICHAITPLQKQGRFSDDESVTMDWQGAALSLAGRYKQQARLLCGPEARTCQSAGLFGDNAQVDPALRDLDVGAWKGQRIGQLDSATLNTWATDSASAVHGGESVGQLCIRVGQWLNSLETHPGHVIAVTHPFVIRAAMLSVMQLPSAMFYRIDVEPLSATELRFNGVWRLRLETSA
>NC_017911.1|WP_014718103.1|2463394_2464714_+|MFS-transporter
MGNPAQDTVRKRRRAFLGATSGHLIEWYDYGVYGFLAVYIGQAFFVSDDPTTSLLASFAAFALSFFIRPLGGLFFGPLADKIGRRKTLIMALVMMTGSTVMLGLLPTYASLGIAAPILLILVRCVQGFSAGGEIGTVTSFISEYAGPGRRGFATCWLMVTAVLGLLLGGAVANGMTWGLGAEVMQEWAWRVPFLIAAPLGFISMYIRLKLEDSPEFLALQRAGQTSRAPLREVWQWKRAIALVFFIITLHSSIFYLVLTFASTYMAKILKFDSGTTLLYVFVASFSAAFVMPFGGAFTDKYGRKPFLMVIGTLATLAMFWLFKSAPTATPATFFAPLMAVAILFGLYASSTYALMSELLPTRIRSTGIAVAYNVPVAVFGGSAPLISTWLIKVTGDITSPWYFYVATGVVSLLALVVLRKEDFVASGHSTAVPASAALA
>NC_017911.1|WP_014718114.1|2484654_2486085_-|PLP-dependent-aminotransferase-family-protein
MFVSAIAFVEGTPKVQQIVEAFSHAIENGEWAPGSKLPSVRELTQILGVSKFTLNEALDRLRGRHLLTSSQGRGYFVAMDSTRPASATWVDLLPQDLLSVLRRPLATASGELRPGGGHLPEDWLNGEAIRQAMRSVVRAPSLRIAGLGTPAGLLPLRQALQQKLHGEGLSVPVEQIITTPNTVQGLDMLMRLLARPGDTVLLDAPCYFNFHANLALHGVKVITIERRPDGFDFAALEQLLAEHRPSLYLTTSVLHNPTGHSFSPSQAFRLLQLTQHYHCHIVEDDLYGDLHPNPPPRLAAVAGLEQVTYLSGFSKSLSANTRVSYVVAAPQLAANLTNMKLMSGGVTSELFEQIVYRMLSEGSYAKHRKRMVQRLMEAGGRVEQWLKRCGCELPMAYEGGMFIWARLPPGVNGELLAQQALKRSMVLAPGALFGYDPAHRDSMRFNVAHSDEPRVQRVFEALLLHGVAHKSKSGPT
>NC_017911.1|WP_014718115.1|2486243_2486426_+|rubredoxin
MKTYMCAPCGFMYVEELGIPEDGIPAGTPWEEVPEDWTCPDCGVTKADFMAINLPERQFA
>NC_017911.1|WP_014718116.1|2486453_2487323_+|sugar-phosphate-isomerase/epimerase
MESKLINATVPFCTGVAHQKYLGAEKGLQTAIEGDCTHWYIDGSLFGEMVDDWTEARIESLQAQITATGVKPVFHGNFKAPLGSDVEAFRSAAVEYVKKEIDIASRLGAPLIIHGGCIVEPKMVLMAKKVALEHYLKSVQELARYAEAKGTDIYLENLSNYVNYRPFHYIFTHEAEYAFVFERLQAHSNVYFFLDAGHANIENGLPAEVVRKYHHLIKGISFSNNNGVQDQHFGIHDGNCDYADVVQAIVETNWKGLVAFETRNQTAKAALADLAVMYRESLTTEIAVA
>NC_017911.1|WP_014718117.1|2487392_2488025_+|LysE-family-translocator
MTSALTLSSFLYFLLFCATMTFSPGPMTLLLLSLGLKDGLRSSIPAQIGASVSYLISILIFAVGFSELIKGNLAITQTIQFVGVAYILYLAYKQWTSSGVSINNAGAVEGSRSLFGKGLLTGFSNPKTIIMFSAVFPQFAGAGEHSSAADIAILGLTFLLLQFASGCLYCYFGQRIKHVLENPKRRVLLQRVTAVLLLGVALMLARGFSH
>NC_017911.1|WP_014718118.1|2488104_2489163_+|diguanylate-cyclase
MPAVGGKGLPLALRLYKSRLLGLTLGFVCVAFGMYPLNPSLWVWAWMLVNAFAWPHLAFQCSLRSANTLRSERRSLLFDSFCGGFWVGAMHFNPLPSVTTLSMMSMNNVAIGGPRFLFAGWVAQALGLGTALLLFTPGFVALTTQAQLYACLPILMLYPLALGWICYRQAVTLARHKRELLALSRTDSLSGLLNHGAWKDHLDLEFQRCRRGPAGAAIALIDIDHFKTINDTYGHVTGDIVLRQLSKVLRQNLRTTDLAGRYGGDEFCVILPDMPLNRATEVMEALRGRFNALAYAQDPTLRVSLSIGLAPYQPSHADSISWLNDADQALYEAKSSGRNRVSSVQGSWLRSV
>NC_017911.1|WP_014718119.1|2489211_2490441_+|M20/M25/M40-family-metallo-hydrolase
MFFTFPRTLLAATLALSFSLPAYSAEPHKQIQQQAEQYKAQALKLLERLVNIDSGSGYEPGLTQVRDIAVDELKQLGFTIELVPDKAANNSHVVATLKGTGKAKILLMAHMDTVFKEGSAAERPFHIKDGRAYGPGVMDDKGGIVAGIYALKVLKSQGFKDYAQITFLLDASEETGSDAASELIRNTAKGHDVTLNLEPGRPADGLVVWRKGSATAVVEVKGKAAHAGVAPELGRNAAMEAAHQILQLGKLGDEDKKTTINFTVLKAGDRTNVIPDQATAKADVRAALPEEFDRIEKDLARVSANKLIPETEVNTSLQRGLPPMPQTAESDKLVAMAQGIYGELGRKLTIEGSGGAADASLSAGVGTPTLDGFGIVGGNIHTPEEYAEVESVVPRVYLLSRMIMELSKR
>NC_017911.1|WP_014718120.1|2490945_2491362_-|hypothetical-protein
MLKHPFLDIPYAPKLRHLLSPFDIYDREETLGEEFARYDINLDTDRRRLIEKYIIEKSSDLSYRHRKVLCDKLGAALSDETFDFSHLLRQAPGYYCTLPWGWSEMDNPKGFFEEIYRLTNEWWKEDLQKASLEDPATW
>NC_017911.1|WP_080643481.1|2491355_2491640_-|hypothetical-protein
MQLSTQFKSHRAQLAVLNEVTTRAERNLPPFTGEDYYGNPVVRIEMQGCGRGYIPNPSDRNNPILDENMDAAIAKFDRETKELYTVFPVSNDQC
>NC_017911.1|WP_014718121.1|2491690_2492002_-|hypothetical-protein
MNNQLTELQQFFGAYFHQDWVDEHATADEVIDAFLLVSSTDVIITVKEEILELLKYYTNESNLLENLLHKQYCYYYYPHEWASGPLWLSHIVRKIENHLLLKQ
>NC_017911.1|WP_144269781.1|2491998_2496711_-|RHS-domain-containing-protein
MISVLANLVLVPMDPEAPKVERVFADFRTCLNTFDTWADSFLSGSALSVEQVFKVGEDVALVAPISSDKPSRTVAQCKAQGGLTLVHLFESTQFVPIGNTPVRLQAVAQDGSPVGAPLHRTIGPSGILEVSDCSRDQQYEITFYPTVSKAHVQALYASYESVIAGLEADLRTAWAEHFKPRWADFAKAPAYKRSGIQGIAFATGLGKALYNLWDNITELYDLLANLKSNSETLLKYLSQAELDALLKLGKDTLAKGLLVLSDEPLLFIYLSALVAWVRMLPPPDMYELLGEITGEVLINLLLIWATRGIGVQLRLGAQVLSGVKSGRARALLELLAKQVVGPRLETHVEAAKPVLLSSAATPIKTVPAVPLKAGDTLVSNPVPMVRGKAQRTTLVRHEPVDDAPAMASNPKGDAAAPADKTVTHGCPVSMVTGEELLTLTDGALDGILPFEWTRLYRTSAVEVDCGLGFGWSHALAHRLVVSGDSVVWTDHENRHTQFPLPSDSRPAITNSLAEAAIYLGSAPDELVLAQASRFYHFRDGVLTAISDAYDNRLRICRDRSGRIERLDNGAGRSLLLRYELDRIVAVDYQVHRAKGREPYVWETEQNLVSYAYDEHGRLVCATNAVGESERYRYDDQHVILERQLAGGASFFWAWERSGKAARCVRHWASFSQMDTRYAWGDDGHVTVHNADGSQEVYVHDDRARLVQRIDPDGAQHYKSYDAKGRLTVEQDPMGAVTAYQYDDAGRLVALFPGDDEPTSYEHDNGFVRVVRRGEAVWKYERNEQGDVTRRIDPDGEVTDYSYNKHGQLTGVWYPDHSCHRLVWNERGQLLEEQLPNGGIKRYRYDDLGRQVACEDEHGALTQYHWDCVGRLIRLVLPGGGCREFSYNPYGKIIAERDELGHITRYEYADGLHLISRRLNADGTQVKYRYDNARLLLTEIENEAGETYQLDYHPSGLIRQETGFDGQRTAYAYDLNGNLLEKTEYGDDDSQLITRYERDHAGRLVRKTLPDSAVVDYAYDRQGNLLSVEDGHWALAYEYDRQNRLTAEHQGWGTLRYGYDACGQLKNLCLPDNNRVTFNHDKGGHLATVELNGEVLTSHLFKSGREHQRQQGQLLSHYHYDDQSRLHAHAVTQQQNHFYQRQYDYDKSGNLTRLLDTRKGEHRYHYDPLARLTRADHSQDVQERFGHNPAGNLLMQDRPGPDIVAANRLMIQGDRHYDYDAFGNLIRERRGKGQQLVTEYRYDCQHRLISVTQPNGQTASYRYDPFGRRISKTVDDITTEFFWQGDKLIAEHHAERHRSYLYEPGSFRPLALLDGFGPKETRPYHYQLDHLGTPQELTSPEGEIVWSAHYRAYGQIARLDVGKIDNPLRFQGQYFDAESGLHYNRHRYYYPDIGRYLTPDPVKLAGGINGYRYVPNPTGWVDPLGLSCKVGICPGSKIDAPAKKIPSGVLDGHEKAGGHLIKKHVERTDYQLVERLEVEPHIPAASTFKTLEDAEALVSKSLASHSQEISKFLQGTKDKHIIREHSSQPVGLSVIRGTTESIPVYKFMLVLIRKPKMPDGYLLLTGYPIEK

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Crispr_ID: NC_017911_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017911_7

2530361-2530455

Orphan

Consensus_repeat	Method
GGCTTGCCTGCGAAGGCGGCCTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017911_7

>merge|NC_017911|7|2530361-2530455|CRISPRCasFinder
GGCTTGCCTGCGAAGGCGGCCTGAAGGCCGACACCTATCTATCTGACCCTACGCGATCCAAATGTGGGAGCTGGCTTGCCTGCGAAGGCGGCCTG

>NC_017911|7|6|2530361-2530455|CRISPRCasFinder
GGCTTGCCTGCGAAGGCGGCCTG	AAGGCCGACACCTATCTATCTGACCCTACGCGATCCAAATGTGGGAGCT
GGCTTGCCTGCGAAGGCGGCCTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017911.1\|WP_014718158.1\|2540885_2541767_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NC_017911.1\|WP_014718156.1\|2537615_2538206_+\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|225765
NC_017911.1\|WP_014718153.1\|2534982_2535660_-\|DUF1028-domain-containing-protein	unknown	unknown	gnl\|CDD\|377639
NC_017911.1\|WP_014718154.1\|2535671_2536082_-\|RidA-family-protein	unknown	unknown	gnl\|CDD\|223329
NC_017911.1\|WP_014718150.1\|2531049_2532465_-\|cytosine-permease	unknown	unknown	gnl\|CDD\|271377
NC_017911.1\|WP_014718145.1\|2525624_2526761_-\|PAS-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_017911.1\|WP_003191905.1\|2540070_2540688_+\|hydrolase	unknown	unknown	gnl\|CDD\|238494
NC_017911.1\|WP_014718151.1\|2532715_2533627_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176104
NC_017911.1\|WP_014718148.1\|2529013_2529412_-\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_014718141.1\|2522894_2523692_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187602
NC_017911.1\|WP_014718140.1\|2521872_2522883_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381378
NC_017911.1\|WP_161937010.1\|2536105_2537437_-\|NAD(P)-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|274942
NC_017911.1\|WP_014718142.1\|2523717_2524128_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176863
NC_017911.1\|WP_014718146.1\|2526750_2527566_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_017911.1\|WP_014718143.1\|2524170_2524668_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|223718
NC_017911.1\|WP_014718157.1\|2538202_2540041_+\|amidohydrolase	unknown	unknown	gnl\|CDD\|224490
NC_017911.1\|WP_014718147.1\|2527698_2528892_+\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NC_017911.1\|WP_014718152.1\|2533840_2534986_-\|acetylornithine-deacetylase	unknown	unknown	gnl\|CDD\|236039
NC_017911.1\|WP_014718144.1\|2524824_2525628_+\|diaminopimelate-epimerase	unknown	unknown	gnl\|CDD\|234768
NC_017911.1\|WP_014718149.1\|2529741_2530233_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181

Protein	Function_ID	Function_description	E-value
NC_017911.1\|WP_014718158.1\|2540885_2541767_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.17742e-86
NC_017911.1\|WP_014718156.1\|2537615_2538206_+\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|225765	COG3224, COG3224, Uncharacterized protein conserved in bacteria [Function unknown].	2.97294e-32
NC_017911.1\|WP_014718153.1\|2534982_2535660_-\|DUF1028-domain-containing-protein	gnl\|CDD\|377639	pfam06267, DUF1028, Family of unknown function (DUF1028). Family of bacterial and archaeal proteins with unknown function. Some members are associated with a C-terminal peptidoglycan binding domain. So perhaps this could be an enzyme involved in peptidoglycan metabolism.	1.48326e-85
NC_017911.1\|WP_014718154.1\|2535671_2536082_-\|RidA-family-protein	gnl\|CDD\|223329	COG0251, TdcF, Putative translation initiation inhibitor, yjgF family [Translation, ribosomal structure and biogenesis].	2.59228e-35
NC_017911.1\|WP_014718150.1\|2531049_2532465_-\|cytosine-permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	8.18695e-71
NC_017911.1\|WP_014718145.1\|2525624_2526761_-\|PAS-domain-containing-sensor-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	9.24411e-39
NC_017911.1\|WP_003191905.1\|2540070_2540688_+\|hydrolase	gnl\|CDD\|238494	cd01012, YcaC_related, YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them. Multimerisation interface seems not to be conserved in all members.	1.81509e-69
NC_017911.1\|WP_014718141.1\|2522894_2523692_+\|SDR-family-oxidoreductase	gnl\|CDD\|187602	cd05344, BKR_like_SDR_like, putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR. This subgroup resembles the SDR family, but does not have a perfect match to the NAD-binding motif or the catalytic tetrad characteristic of the SDRs. It includes the SDRs, Q9HYA2 from Pseudomonas aeruginosa PAO1 and APE0912 from Aeropyrum pernix K1. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	7.23247e-48
NC_017911.1\|WP_014718151.1\|2532715_2533627_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176104	cd08412, PBP2_PAO1_like, The C-terminal substrate-binding domain of putative LysR-type transcriptional regulator PAO1-like, a member of the type 2 periplasmic binding fold protein superfamily. This family includes the C-terminal substrate domain of a putative LysR-type transcriptional regulator from the plant pathogen Pseudomonas aeruginosa PAO1and its closely related homologs. The LysR-type transcriptional regulators (LTTRs) are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of N2 fixing bacteria, and synthesis of virulence factors, to a name a few. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	2.61381e-84
NC_017911.1\|WP_014718140.1\|2521872_2522883_+\|aldo/keto-reductase	gnl\|CDD\|381378	cd19152, AKR_AKR15A, AKR15A family of aldo-keto reductase. The AKR15 family includes Microbacterium luteolum pyridoxal 4-dehydrogenase (PLD), Pseudomonas sp. D-threo-aldose 1-dehydrogenase (FDH), and similar proteins. PLD (EC1.1.1.107) catalyzes irreversible oxidation of pyridoxal. FDH(EC1.1.1.122), also called (2S,3R)-aldose dehydrogenase, or L-fucose dehydrogenase, catalyzes the oxidation of L-fucose to L-fuconolactone in the presence of NADP(+). It is also active against L-galactose, and to a much lesser degree, D-arabinose. FDH (EC1.1.1.122), also called (2S,3R)-aldose dehydrogenase, or L-fucose dehydrogenase, catalyzes the oxidation of L-fucose to L-fuconolactone in the presence of NADP(+). It is also active against L-galactose, and to a much lesser degree, D-arabinose.	2.13855e-145
NC_017911.1\|WP_161937010.1\|2536105_2537437_-\|NAD(P)-binding-domain-containing-protein	gnl\|CDD\|274942	TIGR04046, predicted_flavoprotein_involved_in_K+_transport, flavin-dependent oxidoreductase, MSMEG_0569 family. Members of this protein family belong to a conserved seven-gene biosynthetic cluster found sparsely in Cyanobacteria, Proteobacteria, and Actinobacteria. Distant homologies to characterized proteins suggest that members are enzymes dependent on a flavinoid cofactor.	1.43428e-125
NC_017911.1\|WP_014718142.1\|2523717_2524128_+\|SRPBCC-family-protein	gnl\|CDD\|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	1.09442e-42
NC_017911.1\|WP_014718146.1\|2526750_2527566_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.45104e-29
NC_017911.1\|WP_014718143.1\|2524170_2524668_-\|AAA-family-ATPase	gnl\|CDD\|223718	COG0645, COG0645, Predicted kinase [General function prediction only].	1.44685e-14
NC_017911.1\|WP_014718157.1\|2538202_2540041_+\|amidohydrolase	gnl\|CDD\|224490	COG1574, COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only].	0
NC_017911.1\|WP_014718147.1\|2527698_2528892_+\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	2.39195e-53
NC_017911.1\|WP_014718152.1\|2533840_2534986_-\|acetylornithine-deacetylase	gnl\|CDD\|236039	PRK07522, PRK07522, acetylornithine deacetylase; Provisional.	0
NC_017911.1\|WP_014718144.1\|2524824_2525628_+\|diaminopimelate-epimerase	gnl\|CDD\|234768	PRK00450, dapF, diaminopimelate epimerase; Provisional.	5.97625e-84
NC_017911.1\|WP_014718149.1\|2529741_2530233_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.4858e-12

>NC_017911.1|WP_014718149.1|2529741_2530233_-|GNAT-family-N-acetyltransferase
MPTLTLRNALPTDAARCFEIETSAYEGDEAATLEKITTRIAQYPEGFLILEEDGAVVGFINSGCAHEVVMSDEAFKELVGHVAEAPNVVIMSVVVDPAHQGKGYAKRLMTEFVQRMQAMGKRTLHLMCKAQHVPLYRAMGYTYVRPSPSDHGGMAWHEMVKTL
>NC_017911.1|WP_014718148.1|2529013_2529412_-|hypothetical-protein
MSSINGSAPFVPAYQPAAKHPIDNDVPRKNSLDKQAGEDAEVSNGKGGWKNIGNATRDHANRTRLDRNFLPSDKKTVDDAQVNTRAGYHGTGTLPAFPTWDDKALNDSASNALRQPIDFEIKPDGNGGWTKA
>NC_017911.1|WP_014718147.1|2527698_2528892_+|YgcG-family-protein
MIVLVRQSVFSLLALVFSSLFIAAHADTSPIGVALDQRVIDLTNTLDSGTVLRLKQQLADLEQRKGAQVAVLLVPTTGSSGIEDYANQLFRAWKLGRKDVNDGILLVVAKADRTVRIEVGYGLEGIVTDLLAHRIIEERLTPAFRQGDFAGGIQQGVSALVVLVDGGDLPEVAGPGINPQFFAILAAFVLGALAGTLIAAGKLHWRRALIIAVAATLLLTVLAGGRDWPMFLVAMPLTLLIGGALFGALWQVRTLFYGVIGLLAYILGLVVANHYVDVSFTHWLLWPLGVLVVLGLYLVLVLLMRQTWRASRAGFSVRLLAAVAVYGVAGQVMDGDHDAWLLAFPIASFVALIIFGKVGEGSGSGGGSSSGSSGSSTSSSSSGGGGSSGGGGASGSW
>NC_017911.1|WP_014718146.1|2526750_2527566_-|alpha/beta-hydrolase
MDLRHRNNIHVMGHGPSTLVFSHGFGCNQAMWNALAPHFLERFRVVLYDLVGAGLSDLSAFDKTKYSRLDGYAHDLNEIIDAYAQGPVILVGHSVSAMIGTLADRFLPGRIAAHVMIGPSPRYIDTEEYVGGFQRDDIDDLLDTLDSNYLGWSSAMAPVIMGAPTQPHLSEALTESFCRTEPDIAKQFARVTFLSDNRQDVFGLTTPVLILQSTDDLIAPVAVGEYLHAVLPNSTYCLVENVGHCPHMSAPQACATAMDRFLAPWAAADAR
>NC_017911.1|WP_014718145.1|2525624_2526761_-|PAS-domain-containing-sensor-histidine-kinase
MPVDPLFDSAACALAVTQEDGTILHVNPRLCDWLGFTAAQLLGRRFQDLLAMGGRIFYQTHLAPMLRMHGSVTEVKLDIRHCNGHKVTVLLNANRRQQPDGVVYDLALFGTTDRDKYERELLNAHKQAEALLQEKTATELALQQAQAELSEAYAIAQRRALFAEQMVAIVSHDLKNPLTAIRMASDFLQRGERTAKERQLLGHIGQSSERAHRMIADLLDFTQARVGQGITIKPQPLDLHSVIHRSVDELRVAFPKATLVHHAEGQGDACLDADRVQQMIGNLVANSVAYGDLLQPITITSRLGDNTCAVAVHNHGPAIPQTLLAGLFEPMTRGTDQGSDVRSVGLGLYIVRELARVHGGDVAVSSCASAGTTFTVKF
>NC_017911.1|WP_014718144.1|2524824_2525628_+|diaminopimelate-epimerase
MTLPFVKMHAHGDDFIIIDRRGEDNPITAQIARHLGNRRTGIGFNQLAVVLDCEEAAARVQFWNPDGTRLQTCGSATRGVADRLMHEAGTQSIVLGSDRGLLTCTRADGQRVSVDMGPPSLDWASVPLARAMDTCVLPIDGQPAACSMGNPHCTFFVEDVTALDIEAMGSTLEVHPLFPARTNVHFVQVLDRGHIRLRIWERGGGVPLGSGSCCCAAVVNGIRRGLLDERVEVQCDGGAVTVQWDGRGGVILTGRVEPIMQGTAYLY
>NC_017911.1|WP_014718143.1|2524170_2524668_-|AAA-family-ATPase
MLIVFSGLPGSGKTTIARELARQLGAVYLRIDVIEQALREAAVLVGDVGASGYAVANALALSNLRLGQRVIADCVNPVKESRDAWQAVATAAGVALSNIEVVCTDQQAHRRRVEGRVGDIPGLVPPTWESVQAHEYERWETPPFRLDTAQMTPAEAVAAALLHIG
>NC_017911.1|WP_014718142.1|2523717_2524128_+|SRPBCC-family-protein
MATASSVIEIAVSADQVWQLIGGFNSLPDWLPLIAKSEPSEGGRVRHLTTADGGAIVERLQTFDNVARTYSYTIEASPFPVSAYLATLQVEALTDTSAKVTWSGVFTPAAGTTEAQVEELFAGVYEGGLEALRGNF
>NC_017911.1|WP_014718141.1|2522894_2523692_+|SDR-family-oxidoreductase
MKIDVSGKVAIVSGSTAGIGLGISQALAQSGATVVVIGRDAGKVDDALASIRQAVPAAQLRGVVADLGTVEGAQKLFAAEPRADILVNNLGIFDAVDFFDAPDSEWACFYEVNVISGVRLARHYVPGMVEQGWGRVIFVSSESGVATPADMINYGVTKSANLAVSHGLAKRLAGTGVTVNAILPGPTFTDGLEHMLKDATAESGRSAREEADVFVRHARPTSIIQRAANVEAVANLVAYIASPLSSATTGAALRVDGGVVDSMAI
>NC_017911.1|WP_014718140.1|2521872_2522883_+|aldo/keto-reductase
MSLKDTLPGVLGFGTAPLGNMFRAIPEAEAQATVQAAWNQGVRYFDTAPFYGSGLSEIRLGQALSNYHRDDYVLSTKVGRVILDEVEETARDLGEKSGVFEHGRPNKIINDYSADATLRSIEDSLTRLQTDRLDIVWVHDIAQDFYGDQWLEYFNQARTGAFKVLTRLREQGVIKAWGLGVNRVEPCELTLDLAEAQPDGFLLAGRYTLLDHDRALQRLMDAAHAQQVEIVVGGPYSSGILAGGAHFEYQQAGPAIIAKVEQIKAIAQAFGVSIKAAALQFSLAHPAVAAVIPGASRPGRIAEDVAALSEQIPAAFWQALREARLISDRAPLPLSR
>NC_017911.1|WP_014718150.1|2531049_2532465_-|cytosine-permease
MVTTATSSAPLIEKHTIGYVPPEDRHGKVRDLFTLWFGGNIAPLPIVTGALGVQLFHLNLVWGIVAILVGHLVGGVLMALHSAQGPQMGIPQMIQSRAQFGSLGALLVVVIAGVMYIGFFASNIVLAGKSLHGVVDAVPVPVGIVIGAIGSGIIGIIGYRFIHVLNRIGTWVLGAGIVLGFGYIFTHVQTTDFLTRGSFNISGWLATVSLAALWQIAFAPYVSDYSRYLPADVPVAATFWTTYLGSALGSSLAFIFGAVAVLATPVGMDTMDAVKLATGAIGPLMLVLFLLSVISHNALNLYGAVLSIITLVQTFAYRWIPTAKSRAVISIIVLAACSIAAVFASQDFIGHFVDMVLVLLVVLVPWTAINLIDFYAIHKGQYDIASIFRVDGGIYGKYNPQALLAYAVGIVVQIPFMNTPLYVGPISQHINGADFSWVVGLVVTSPLYFWLASRDSAYKRRMDSGKLVGGV
>NC_017911.1|WP_014718151.1|2532715_2533627_+|LysR-family-transcriptional-regulator
MAAYNLRQLRYFVTTAECGSVAEASRKLYIAQPSVSTAIKQLEDSFGVQLFIRHHAQGVSLTPSGARFYRKALELLRVAHEFEQNALADNDVVAGQIDIGCFETVAPLYLPRLIAGFKARWPGVEIRIRDGEQQELVQALTAGSIDVAMLFEHDLGSTIETTPLMPPQQPYALLPADHRFAQQAKVSLADLVLEPMILLDVLPSRTYFVSIFEERGLTPNIVFSSPSIEMVRGMVGRGFGFSILVTKPFSEYTYDGQKVVCIPLVETVTGSGLSAVWLRRAPLTKPVQLFVDYCREELARLLG
>NC_017911.1|WP_014718152.1|2533840_2534986_-|acetylornithine-deacetylase
MSRSRDLLETLVGFDTTSRESNLQLIEYVRDYLAGLGVTSELVYNAQRSKANLFASIGPVELPGIVLSGHTDVVPVDGQPWSLPPFTLTERDGKLFGRGTADMKGYIACVLALVPALVKAPLRLPVHIALSYDEEVGCLGVRSLLAVLEQRPVKPMLCIIGEPTELKPVLGHKGKLAMRCDVQGQACHSAYAPSGVNAIEHAAELIGELGRIGQRLRARQDPRFDPPFSTVQTGMINGGKALNIVPADCRFDFEVRALPSMDPGEVAEELQAYARQQVLPRMQAVSKQSSIRFTELSAYPGLVTDERSQAAQLIATFCDSQAFGTVAFGTEGGLFDAVGIPTVVCGPGSMDQGHKPDEFVSLEQLDGCDAMLQRLLGFIST
>NC_017911.1|WP_014718153.1|2534982_2535660_-|DUF1028-domain-containing-protein
MTFSIVGRCAETGQLGIAISSSSIAVGARCPWLRPGVGAVSTQNITLPALGPDVLDGLEQGLAPADAVDKALTRNGYSQYRQLTAIDHLGRSVHFSGSQTLGTHHAVSGEQCVAAGNMLAAPEVITAMVTAFEQGEGQLADRLLAAMHAAIAAGGEAGPVHSAALVVVGELTWPIINLRVDWADEAPIGELQKLWDAYRPQVQDYIDRALAPDRSPGYGVAGDDR
>NC_017911.1|WP_014718154.1|2535671_2536082_-|RidA-family-protein
MPTHTRIRMFNTKETYPNQSLDNDLCQAVRAGNTVYVRGQVGTDFDGNLVGLGDPRAQAEQAMKNVKQLLEEAGSDLSHIVKTTTYLIDPRYREPVYQEVGKWLKGVFPISTGLVVSALGQPQWLMEIDVIAVIPE
>NC_017911.1|WP_161937010.1|2536105_2537437_-|NAD(P)-binding-domain-containing-protein
MPELNPTALRKDRDMTVAITKIDTLVVGAGQAGVAMSEHLSKQGVPHLVLERSRIAERWRTGRWDSLVANGPAWHDRFPGLHFDDVPADGFAPKERVADYFEAYARKFNAPIRTGVDVTSVVRNEGRPGFTVHTSEGVIEANRVVAATGPFQKPVIPAIAPKDTALHQIHSADYRNPGQLPAGAVLVVGAGSSGVQIADELQRSGRQVYLSVGAHDRPPRAYRNRDFCWWLGVLGEWDQAAMKPGREHVTIAVSGAHGGKTIDFRELAQQGMTLVGLTHAFDGTVATFQPNLVENLARGDENYLALLDAADAYIERNGLDLPLEPEARRVFPDAECIKQPILTLDLAEAGITSIIWATGFAVDYSWLQVDAFDAAGKPQHQRGVSSEAGIYFLGLPWQSRRGSSFIWGVWHDAKYVADHIAIQRQYLEYREAAPVARQSPVST
>NC_017911.1|WP_014718156.1|2537615_2538206_+|antibiotic-biosynthesis-monooxygenase
MESTANTRPDEVVTLVVKHRVKPGFEVEYEAWLRRIVRIAGERPGHLGVDVVRSQQNGMALFTCVLRYSSTNALELWLGSPQRQALIDEAAPMLADGDQTEIGAANEFWFTPQAEGGAKPPRWKQAVVSLFVILPQTLLLPFIWGPILRLHPFLSNYVVSTFLVTLTIVLLVVYLLMPAATRLFAPWLEASVKETL
>NC_017911.1|WP_014718157.1|2538202_2540041_+|amidohydrolase
MNADLILFNGQFHTVDRENPRATAVAIHQGRFVAVGTDGEAMALRGSGTQVIDLKGRTVIPGLNDSHLHLIRGGLNYNLELRWEGVPSLADALRMLKDQADRTPTPQWVRVVGGWNEFQFAEKRMPTLEELNQAAPDTPVFVLHLYDRALLNRAALRVAGYTKDTPNPPGGEIVRDSNGNPTGMLVARPNAMILYSTLAKGPKLPLEYQVNSTRQFMRELNRLGLTSAIDAGGGFQNYPDDYAVIEQLAKDQQLTVRIAYNLFTQKPKEELSDFKHWTGSVTLHQGDDYLRHNGAGEMLVFSAADFEDFLEPRPDLPLTMEQELEPVVRHLVEQRWPFRLHATYDESISRMLDVFEKVNRDIPFNGLPWFFDHAETITPKNIERVRALGGGIAIQDRMAFQGEYFVERYGAKAAEATPPIKRMLAEGVPVGAGTDATRVSSYNPWTSLYWMVSGRTVGGLELHAEGLPRLTALELFTHGSAWFSSEQGKKGQIKVGQLADVAALSADFFSVEEEAIKWIESVLTVVGGKVVYGAGDFEDFAPPRVPVLPDWSPVVKVPGHWRPTSPMQAQVHQCSGPCGVHAHSHEKARLSSVPVSDFQGFWGAFGCSCFAF
>NC_017911.1|WP_003191905.1|2540070_2540688_+|hydrolase
MTYKRLNKDDAVVLLVDHQTGLISLVQDFSPNEFKNNVLALADVAKFFNLPTILTTSFESGPNGPLVPELKELFPDAPYIPRPGQINAWDNEDFVKAVKATGRKQIIIAGVVTDVCVAFPTLCALDEGFEVFVVTDASGTFNETVQQAAWARMTAAGAQLVNWFSVACELQVDWRNDMEGLANLLSPRIPNYRNLMNSYSAFAAK
>NC_017911.1|WP_014718158.1|2540885_2541767_+|LysR-family-transcriptional-regulator
MNPFEDMRLFCQVMESGSFTAAAEQLGLSKQFVSRRLIQLEDRLGVRLLNRSTRRLDVTPLGQSYYESALRLLGEVEQVEQGIAGQNSEPRGTIRLSAPLSFAMAHLGCLLPLFLRQHPQVCVEVDLSDRPVDLIGEGYDLVLRIGTLEDSTLIARRIAAIERVYCASPDYLALRGTPSKPEDLTTHDCLPYGHGRQVQWRFKGKVQALSVSGRMRVNNGDLLRDTAIAGLGVTYLPTFIVSEALKDGRLVKVLEDFAPEALTLSAVYPQHRQSSRPVQALVEFLRERLASGC

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Crispr_ID: NC_017911_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017911_8

3299402-3299510

Orphan

Consensus_repeat	Method
CTGTGAGGCCGCCTTCGCAGGCAAGCCAGCTCCCACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017911_8

>merge|NC_017911|8|3299402-3299510|CRISPRCasFinder
CTGTGAGGCCGCCTTCGCAGGCAAGCCAGCTCCCACAATTTGATCGCGGGGCGTCAGGTAGGTAGTCGTCGGCTGTGAGGCCGCCTTCGCAGGCAAGCCGGCTCCCACA

>NC_017911|8|7|3299402-3299510|CRISPRCasFinder
CTGTGAGGCCGCCTTCGCAGGCAAGCCAGCTCCCACA	ATTTGATCGCGGGGCGTCAGGTAGGTAGTCGTCGG
CTGTGAGGCCGCCTTCGCAGGCAAGCCGGCTCCCACA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017911.1\|WP_014718705.1\|3293650_3296245_+\|autotransporter-outer-membrane-beta-barrel-domain-containing-protein	unknown	unknown	gnl\|CDD\|238654
NC_017911.1\|WP_003190934.1\|3303632_3304334_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_017911.1\|WP_014718716.1\|3308874_3309516_+\|DUF1345-domain-containing-protein	unknown	unknown	gnl\|CDD\|377769
NC_017911.1\|WP_014718703.1\|3291073_3292555_+\|xylulokinase	unknown	unknown	gnl\|CDD\|198375
NC_017911.1\|WP_014718717.1\|3309588_3310428_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NC_017911.1\|WP_014718701.1\|3288334_3289438_+\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	unknown	unknown	gnl\|CDD\|236947
NC_017911.1\|WP_014718714.1\|3304505_3305648_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|169982
NC_017911.1\|WP_014718706.1\|3296315_3296585_-\|DUF1652-domain-containing-protein	unknown	unknown	gnl\|CDD\|311697
NC_017911.1\|WP_005788583.1\|3287480_3288311_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NC_017911.1\|WP_014718710.1\|3300517_3301039_+\|DUF3455-domain-containing-protein	unknown	unknown	gnl\|CDD\|314761
NC_017911.1\|WP_014718715.1\|3305654_3308753_+\|multidrug-efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|273335
NC_017911.1\|WP_014718712.1\|3301652_3302327_+\|anti-sigma-factor	unknown	unknown	gnl\|CDD\|227648
NC_017911.1\|WP_014718713.1\|3302327_3303629_-\|two-component-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|236724
NC_017911.1\|WP_003190946.1\|3296954_3297155_+\|ParD-like-family-protein	unknown	unknown	gnl\|CDD\|314732
NC_017911.1\|WP_014718704.1\|3292567_3293506_+\|carbohydrate-kinase	unknown	unknown	gnl\|CDD\|238572
NC_017911.1\|WP_014718702.1\|3289456_3290938_+\|mannitol-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|223324
NC_017911.1\|WP_014718708.1\|3297962_3299087_-\|dimethyl-sulfone-monooxygenase-SfnG	unknown	unknown	gnl\|CDD\|274923
NC_017911.1\|WP_014718709.1\|3299539_3300325_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NC_017911.1\|WP_014718711.1\|3301125_3301656_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|171568
NC_017911.1\|WP_044483261.1\|3297154_3297925_+\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|235576

Protein	Function_ID	Function_description	E-value
NC_017911.1\|WP_014718705.1\|3293650_3296245_+\|autotransporter-outer-membrane-beta-barrel-domain-containing-protein	gnl\|CDD\|238654	cd01344, PL2_Passenger_AT, Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43, AIDA-1 and IcsA, as well as, the less characterized ShdA, MisL, and BapA autotransporters.	5.35081e-41
NC_017911.1\|WP_003190934.1\|3303632_3304334_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.49664e-87
NC_017911.1\|WP_014718716.1\|3308874_3309516_+\|DUF1345-domain-containing-protein	gnl\|CDD\|377769	pfam07077, DUF1345, Protein of unknown function (DUF1345). This family consists of several hypothetical bacterial proteins of around 230 residues in length. The function of this family is unknown.	9.71311e-66
NC_017911.1\|WP_014718703.1\|3291073_3292555_+\|xylulokinase	gnl\|CDD\|198375	cd07809, FGGY_D-XK_1, D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases. This subgroup is composed of D-xylulose kinases (XK, also known as xylulokinase; EC 2.7.1.17) from bacteria and eukaryota. They share high sequence similarity with Escherichia coli xylulokinase (EcXK), which catalyzes the rate-limiting step in the ATP-dependent phosphorylation of D-xylulose to produce D-xylulose 5-phosphate (X5P) and ADP. Some uncharacterized sequences are also included in this subfamily. EcXK exists as a dimer. Each monomer consists of two large domains separated by an open cleft that forms an active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. The presence of Mg2+ or Mn2+ might be required for catalytic activity. Members of this subgroup belong to the FGGY family of carbohydrate kinases.	0
NC_017911.1\|WP_014718717.1\|3309588_3310428_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	4.63379e-25
NC_017911.1\|WP_014718701.1\|3288334_3289438_+\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	gnl\|CDD\|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	0
NC_017911.1\|WP_014718714.1\|3304505_3305648_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|169982	PRK09578, PRK09578, MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit.	5.22225e-109
NC_017911.1\|WP_014718706.1\|3296315_3296585_-\|DUF1652-domain-containing-protein	gnl\|CDD\|311697	pfam07865, DUF1652, Protein of unknown function (DUF1652). This is a family containing hypothetical bacterial proteins.	3.28539e-16
NC_017911.1\|WP_005788583.1\|3287480_3288311_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	4.72072e-73
NC_017911.1\|WP_014718710.1\|3300517_3301039_+\|DUF3455-domain-containing-protein	gnl\|CDD\|314761	pfam11937, DUF3455, Protein of unknown function (DUF3455). This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 174 to 251 amino acids in length.	7.40032e-40
NC_017911.1\|WP_014718715.1\|3305654_3308753_+\|multidrug-efflux-RND-transporter-permease-subunit	gnl\|CDD\|273335	TIGR00915, Probable_aminoglycoside_efflux_pump, The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate].	0
NC_017911.1\|WP_014718712.1\|3301652_3302327_+\|anti-sigma-factor	gnl\|CDD\|227648	COG5343, COG5343, Uncharacterized protein conserved in bacteria [Function unknown].	7.6192e-39
NC_017911.1\|WP_014718713.1\|3302327_3303629_-\|two-component-sensor-histidine-kinase	gnl\|CDD\|236724	PRK10604, PRK10604, sensor protein RstB; Provisional.	1.56269e-78
NC_017911.1\|WP_003190946.1\|3296954_3297155_+\|ParD-like-family-protein	gnl\|CDD\|314732	pfam11903, ParD_like, ParD-like antitoxin of type II bacterial toxin-antitoxin system. ParD-like antitoxin is a family of archaeal and bacterial proteins of a type II bacterial toxin-antitoxin system. Many of the cognate toxins for these molecules fall into family ParE-like_toxin, pfam15781. Gene-pairs are expressed from the same operon, the toxin of the pair being expressed first, eg, for UniProtKB:Q3AQ93 and UniProtKB:Q3AQ94.	1.14349e-26
NC_017911.1\|WP_014718704.1\|3292567_3293506_+\|carbohydrate-kinase	gnl\|CDD\|238572	cd01167, bac_FRK, Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into glucose-6-phosphate. This is in contrast to FRKs [or ketohexokinases (KHKs)] from mammalia and halophilic archaebacteria, which phosphorylate fructose to fructose-1-phosphate.	1.70773e-96
NC_017911.1\|WP_014718702.1\|3289456_3290938_+\|mannitol-dehydrogenase-family-protein	gnl\|CDD\|223324	COG0246, MtlD, Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism].	0
NC_017911.1\|WP_014718708.1\|3297962_3299087_-\|dimethyl-sulfone-monooxygenase-SfnG	gnl\|CDD\|274923	TIGR04021, LLM_DMSO2_sfnG, dimethyl sulfone monooxygenase SfnG. This family of FMNH2-dependent members of the luciferase-like monooxygenase (LLM) family includes SfnG, a monooxygenase that converts dimethylsulphone (DMSO2) to methanesulphonate. This step can be followed immediately by methanesulfonate sulfonatase (an alkanesulfonate monooxygenase - see TIGR03565) for the FMNH2-dependent conversion an inorganic form. [Central intermediary metabolism, Sulfur metabolism].	0
NC_017911.1\|WP_014718709.1\|3299539_3300325_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	5.36268e-29
NC_017911.1\|WP_014718711.1\|3301125_3301656_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|171568	PRK12537, PRK12537, RNA polymerase sigma factor; Provisional.	3.5028e-97
NC_017911.1\|WP_044483261.1\|3297154_3297925_+\|type-I-methionyl-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	6.0746e-143

>NC_017911.1|WP_014718708.1|3297962_3299087_-|dimethyl-sulfone-monooxygenase-SfnG
MSQQAVKFAYWVPNVSGGLVVSKIEQRTHWGIEYNRKLAQLAEAAGFEYGLTQIRFTAGYGAENQHESVAFSHALLAATTTLKVIAAILPGPWQPALAAKQLATIDQLTNGRIAVNIVSGWFKGEFQAIGEHWLEHDERYRRSEEFIRALKGIWTQDDFTFKGDFYRFNQYTLKPKPLGQPEIFQGGSSRAARDMAARVSDWYFTNGNTPEGVKAQVDDIRAKAAANHHSVKVGVNAFVIARDTEEEARAVLAQIIDQADPEAVNAFGDAARQAGKASPEGEGNWAKSSFEDLVQYNDGFKTNLIGTPQQIAERIVALKAVGVDLVLAGFLHFQEEVQYFGKRVLPLVRELEAKADAGASLLAKNVNEKVASLV
>NC_017911.1|WP_044483261.1|3297154_3297925_+|type-I-methionyl-aminopeptidase
MIKTPAQLAVMREAGRLLAQVFDMLDGFVAAGRSTLELDSAVEAFIRNDLKARPASLGQYDYPFCINTSINEVVCHGMPSAKQILKDGDIINIDITLEKGGFIADASKMYMIGNVTPKARRLVDMTFEAMWAGIRQVKPGARLGDIGHAIQSHAQANGYSVVREYCGHGIGRQMHEEPQILHFGRPGTGLELREGMVFTIEPMLNHGSAKTRSLKDGWTVVTKDNSLSAQWEHTVAVTADGVEVLTLQATQTFYTP
>NC_017911.1|WP_003190946.1|3296954_3297155_+|ParD-like-family-protein
MGIVKITDQLHEQLRLASAAMDRSINAQAEFWIKIGLLAELNPHLPYNELINKLLLDKPDLIRGRS
>NC_017911.1|WP_014718706.1|3296315_3296585_-|DUF1652-domain-containing-protein
MLSELELRSIIEGSFLPKRCECTKAEDASLTIRVYDDRDRDRVDLEVKGIHPDKLDSSRAICNLITGLREDLKQSHAPVLQRAGARGYH
>NC_017911.1|WP_014718705.1|3293650_3296245_+|autotransporter-outer-membrane-beta-barrel-domain-containing-protein
MQKPSGFSTRAVLAVGLISLQYMNPQPSHAACVLTPGTGNDTYTCNNGSSAGLTDLSGDNSLTLSTGGAINGDVTFGPGIDTVEIRDGRVTGIVQQGDGVDRVVMMGGRIGGLFQGDGRDVLEMYDGIIDEAFEDGDVAYQRGGKIGRVNMKLDKNFYEMTGGEIRENLVTGFDTDTIIISGGTIGGNISTSGGDDSITVSGGVINGEIRASVGNDTFKWLGEGRINSRVLMGDGDDTVLLQGLNESKLNHTPFIDGGLGNDQLIFDATTSSTAARYIGLERVSLTKNSRLDLAGDFFLGDSGSNTGMFNIDGSSTLAVAQGGIRPYTAGQLATLNNAGTVDMTTDNSATSVLTVHGNYVGNNGQLHLQTVLGDENSATDKLVVSDGNISGHTQLSVSNLGGIGGLTQNNGIEVVQALNGAVSSNDAFALKGSVSAGAYEYLLFKGGTLANTKNSWFLRSSVVAVQPPAVPPVPPTPAVVVPVPPIPATPPVVDSDEPSVEPPTAQPQPPIEPAAPPPSQVAAATSPQSAASNPVLPTAVAGAAPIPLYRLEVPVYSVDIPAAQLMTLQALGTFHERQGEQSLLTETGAVPAGWGRAYGSDFNKSWSGTVAPSFDGTVKGYQVGHDLYAAETSGGQTQRLGLFIGQSRLRGDVKGFAMGWQNHRSGRVKLDGDNFGAYWTLTDPTGWYVDLVAMGTRLDGDNKSDRGVKMDTKGHALALSAEAGYPFRLSEHWEMEPQAQVIGQKIDLDNQHDGISKVSFDSQEYWTGRIGARLKGRYLVSNTPVEPYLRANVWHTFGGSDTVTFDGVDRIKSDHKSSTADMGIGVVAQLSSTVSVYMEGNYGTQLDDNNFEGVSGNFGVRARW
>NC_017911.1|WP_014718704.1|3292567_3293506_+|carbohydrate-kinase
MYLVCGEALFDFFSEEDASGQAAKLSYKAIAGGSPFNVAVGLRRLGIESGLFAGLSTDYLGRRLQQVLNDEGICERFLVAFDAPTTLAMVAVGANGSPQYSFRGEGCADRQLQLTHLPPLGDEIRGLHVGSFSLVVQPIGDTLLNLVKRESGKRLISLDPNVRLNPQPDIHLWRARVAELVQHADLIKVSDEDLHLLYPDQTPESVLQGWLQHRCQLVFLTRGGDGASVFSRQHGSWSQPAVKVVMADTVGAGDTFQAALIAWLTEQQLDSVDGLQRLSREQIDAMLGFAIRAAALTCGKTGPDLPYRQQLA
>NC_017911.1|WP_014718703.1|3291073_3292555_+|xylulokinase
MTQQNLFLGIDCGTQGTKAIVLDASSGKVLGLGAAAHTLISGANGRREQHTQEWLDAFTEATHRALQQAGVDGQDILGIGVSGQQHGLVLLDEQGEVLRPAKLWCDTETAPENDRLLQHLGGERGSLERLGVAIAPGYTVSKLLWTREQHPDVFARIAHILLPHDYLNYWLTGRACAEYGDASGTGYFNVRRREWDVALLQHIDPSGRLQAALPTLIEADQAVGTILPAIAERLGINPNAVVSSGGGDNMMGAIGTGNIAPGVITMSLGSSGTVYAFADQPNVSPQASVATFCSSSGGWLPLICTMNLTNATGVIRELFDLDLDAFNALVEQASIGADGVSMLPFLNGERVPALPHATGSLQGLTMTNLTRANLCRAVVEGTTFGLRYGLDLLRQTGLQSQSIRLIGGGSKSPLWRQMVADIMHTEVVCTEQSEAAALGAAIQAAWCQSGEPLASLCDKCVSIDPASRTLPVAANVSAYQQAYERYQQHVATL
>NC_017911.1|WP_014718702.1|3289456_3290938_+|mannitol-dehydrogenase-family-protein
MKLNKANLTQLAPQVQLPAYAIADTRQGIAHIGVGGFHRAHQAFYTDALMNTGEGLDWGICGVGLRSEDRKARDDLAGQDYLFTLYELGDTDDTQVHVIGSISDMLLAEDDAQALIDKLASPQIRIVSLTITEGGYCIDDSNGEFMAHLPQIQHDLAHPRAPKTVFGFICAALTQRRAAGTPAFTVMSCDNLPHNGAVTRKALLAFAALHDAGLHDWIKANVSFPNAMVDRITPMTSTAHRLQLHDQHGIDDAWPVVCEPFVQWVLEDKFVNGRPAWEKVGVQFTDDVTPYEEMKIGLLNGSHLALTYLGFLKGYRFVHETMNDPVFVAYMRAYMDLDVTPNLAPVPGIDLTEYKQTLVERFSNQAIADQLERVCSDGSSKFPKFTVPTINRLIADGRETDRAALVVAAWALYLKGVDENGARYSIPDPRAAFCQDLVSDDALISQRLLGVEEIFGTAIPKSAAFVAAFERCYASLRDKGVTTTLQNLLNKPD
>NC_017911.1|WP_014718701.1|3288334_3289438_+|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC
MANLKIKNLQKGFEGFSIIKGIDLEVNDKEFVVFVGPSGCGKSTLLRLIAGLEEVSDGTIELDGRDITEVPPAKRDLAMVFQTYALYPHMSVRKNMSFALDLAGVDKQLVESKVGEAARILELGPLLERKPKQLSGGQRQRVAIGRAIVRNPKIFLFDEPLSNLDAALRVQMRLELARLHKELQATMIYVTHDQVEAMTLADKVVVLNSGRIEQVGSPLELYHQPANLFVAGFLGTPKMGFLKGQVTRVDSQGCEVQLDAGTLISLPLSGATLSVGSAVTLGIRPEHLEMATPGQTTLTVTADVGERLGSDTFCHVITRNGEPLTMRIRGDMASQYGETLQLHLDPAHCHLFDTDGVAVARPLRAAA
>NC_017911.1|WP_005788583.1|3287480_3288311_+|carbohydrate-ABC-transporter-permease
MTLQQSRRLQSLLLGTLAWAIAILIFFPIFWMVLTSFKTEIDAFATPPQFIFTPTLENYLHINERSNYFAYAWNSVVISFSATALCLLISVPAAYSMAFYETQRTKGTLLWMLSTKMLPPVGVLMPIYLLAKSFGLLDTRIALIIIYTLINLPIVVWMVYTYFKDIPKDILEAARLDGATLWQEMVRVLLPIAKGGLASTVLLSLILCWNEAFWSLNLTSSSAAPLTALIASYSSPEGLFWAKLSAVSTLACAPILIFGWISQKQLVRGLSFGAVK
>NC_017911.1|WP_014718709.1|3299539_3300325_-|sulfite-exporter-TauE/SafE-family-protein
MDVGNIGFVVAGLIVGFIVGMTGVGGGSLMTPILLWFGINPATAVGTDLLYAAITKSGGVLVHSKNKNIDWTITGWLTLGSVPAVLLTLWFLASLHTDPSAMNAVIKQALGVVLLLTALAILFKKSLLAFAQRHAGDSYHLRPRNLNALTVVTGAILGTMVALTSIGAGALGTVALFILYPFLATRRLVGTEIAHAVPLTLVAGLGHASMGNMDWHLLGFLLMGSLPGIYMGSHMTGRIPDGVLRPCLAVMLMAVGYKLAF
>NC_017911.1|WP_014718710.1|3300517_3301039_+|DUF3455-domain-containing-protein
MNAKTLLCLSSLLLAAPSAFAQAGLPDSIKVPDGHKVAMHTTGVGEITYECRDKANAAGQTEWTFVGPKAVLNDRNGQQVGTYFGPPATWQAKDGSTITGTQLAVAPSSPGNLPYQLVKANPAEGKGAMSGVVYIQRVALKGGVAPAAPCTTANKGAKEMVKYQADYLFWAAN
>NC_017911.1|WP_014718711.1|3301125_3301656_+|sigma-70-family-RNA-polymerase-sigma-factor
MAELIFDYQVCLLACARGDHRALHQLYEQDSSRLLGVALRITRNKALAEDIVHDAFIKIWHGAHSFDPLRGSARGWVFSVTRHLALDVVRSAGRDVPLDDQYEPLAEPAQSIEFAARSGQIHQCLERLDPTRRTCILHAYVDGYSHSEIAQKLSTPLGTVKAWIKRSLAALRECMA
>NC_017911.1|WP_014718712.1|3301652_3302327_+|anti-sigma-factor
MNDSLDELASEYVLGTLPAEQRAEVQQRLAHDAALRAAVDAWEQRLLPLVALAQPVPPSAQLWRRIERRIKIAETGVAWWNLLAFWRGLSAVGLMASVVLAALLLTRPPMTAPSFVVVLMAPQSQAPGWVVQASDNRQIQLIPLGVMEIPADKALEFWTKADGWQGPVSLGLVKPGQTLSVPLDKLPPLAPNQLFELTLEGPNGSPTGKPTGPIHGIGRAVKVL
>NC_017911.1|WP_014718713.1|3302327_3303629_-|two-component-sensor-histidine-kinase
MFRVLLRLYLITIVTYSAAIYLIPKLVIQLFEHRYMNYNIEQSRGLQKLMVKQYQRAPVERWSQVTDQLSRDFAPLKVQLLLRQDARYTPEEEQLLEQGKPVIRLGEWGWMEEISSPINQQFAVKLTVPPDPLDMNLLYWSMNVLVGAALLACLLVWLRPHWRDLERLKSTAALLGKGHLEARTGLAPSSSIGGLAAVFDTMADDIEHLLNQQRDLLNAVSHELRTPLTRLDFGLALALSEDLPLASRERLQSLVAHIRELDELVLELLSYSRLQNPAQLPERVEVALDEFIDSVLGSVDDELENPEIVIDVALDCAVERFSLDPRLTARALQNLLRNATRYCDNRIQVGVRVCPKGCEIWVDDDGIGIPADQRERIFEPFYRLDRSRDRATGGFGLGLAISRRALEAQGGTLTALASPLGGARFRVWLPNLS
>NC_017911.1|WP_003190934.1|3303632_3304334_-|response-regulator-transcription-factor
MPNILLVEDDAALSELIASYLERNGYHVSVLSRGDHVRERARLNPPDLVILDLMLPGLDGLQVCRLLRADSAGLPILMLTARDDSHDQVLGLEMGADDYVTKPCEPRVLLARVRTLLRRSSLSEPQVASDQIVMGNLCIDLSERTVTWREQAVELSSGEYNLLVVLARHAGEVLSRDQILQRLRGIEFNGTDRSVDVAISKLRRKFDDHAGEARKIKTVWGKGYLFSRSEWEC
>NC_017911.1|WP_014718714.1|3304505_3305648_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MSKNLFAPFCLLALTLALSACGQSADETPQMPLAKVRIETLQAKPLSITSELSGRIAAPRIAEVRARVAGVVMQRVFNEGHDVKQGDVLFRIDPAPFKADLDSALANLSKAEANAFQARLQEQRYSQLVEGNAISGQEYDNARAALRQTNAEVAANKAAVERARLNLGYATVTAPISGRIGRALVTEGALVGQNEATPLAIIQQLDPIHADLTQSTRELNDLRRAFRAGSLKQVGQDQAKATLIQDDGSLYPLPGKLLFADISVDPGTGQIILRSEFPNPDLDLLPGSFVRVRVEQAVDKQGLSVPQRAITRDSAGIPMVLLLDAEQTVSQQPVELGAVVDNRWIVTSGLKPGDRIIVEGVQHARPGEKVEVDDSPLVKE
>NC_017911.1|WP_014718715.1|3305654_3308753_+|multidrug-efflux-RND-transporter-permease-subunit
MPQFFIDRPIFAWVVALFILLAGFLAIPQLPVAQYPNVAPPKVEIYAVYPGASAQTLDESVVSLIEQELNGADHLLYFESQSSLGSATITATFQPGTDPEMAQVDVQNRLKVVEPRLPQAVTQQGLQVEKVSAGFLLLVTLTSNDGKLDDVALSDYLARNVMNELKRLDGVGKAQLYGAERAMRIWIDPQKLIGFNLTPADVNAAISAQNAQVSAGSIGDLPGTHTQEITAAVLVKGQLSTPAEFADIVLKANPDGSTVRIGDVARVEVGSQEYQFSTRLNGKPSTAVSVQLSPGANALSTATLVRAKMDELSRYFPANVEYKIPYDTSPFVKVSITKVVYTLLEAMALVFAVMFLFLQNVRYTLIPTLVVPIALMGTFATMLLLGFSINVLTMFGMVLAIGILVDDAIVVVENVERIMATEGLSPKEATKKAMGQITGAIIGITLVLVAVFLPMAFMPGSVGVIYQQFSLSMATSILFSAFLALTLTPALCATLLKPIAKGEHHAKVGFFGWFNQRFEHLTNRYEGWVAYALKRSGRYLLIYLVLLVGMGLLFSRLPSSFLPVEDQGYTITDIQLPPGASKNRTVQVAEQIEAHNAGEPGVGDTTMIMGFSFSGSGQNAALAFTTLKDWSERGSDDSASSIADRANMAFSELKDAIAYAVLPPPVDGLGTSSGFEFRLQDRGGVGHAGLMAARTELLDAAAKSPILANVRESALAEAPQVQLEVDRKQANALGVSFADVGNVLSSAIGSAYINDFPNQGRMQRVVVQAEGDQRSQVADLMKIHVRNNAGKMVPLSAFVEAKWTQGPTQLTRYNGYPAIAISGEAAPGHSTGEAMNEIQRLVRQLPAGLGQEWTGLSLQERLSGSQAPLLLGLSLLIVFLCLAALYESWSIPTSVLLVVPLGVLGAVLAVSLRGMPNDVFFKVGLITIIGLSAKNAILIIEFAKDLYDQGEDLIDATLKAARLRLRPIIMTSLAFILGVVPLAIATGASSASQQAIGTGVIGGMITATLAVVFVPVFFVVVMKLVRKRHKPN
>NC_017911.1|WP_014718716.1|3308874_3309516_+|DUF1345-domain-containing-protein
MPFLARTHPRLSSAAVLGLAVGILVPADTLASKVLIGWNIGVWTYLLLMLWLTIRAKAEDVKRIAEIEDENAGLVLFMVCIAAIASLATITFELVGSKDLATSERLLHYGFTGLTVIGSWLLIGVIFSVHYARLYYTWPGKEPALRFAEGLLTPNYWDFLYFSFTIGVAVQTSDVGVATRSLRKVVLGQSLIGFLFNTAILGFSINIAAGLFG
>NC_017911.1|WP_014718717.1|3309588_3310428_+|AraC-family-transcriptional-regulator
MPAHNWIDLSQDADTGIETLRAHFEGHAYDPHWHDSYLVGVTEQGVQQFNCRRMRHDSVPGQVFLLEPGELHDGNAPTVDGFTYRMLYLDPQWLEREIASVFEEAPAHHQLSFARTLASDPRLALATSQAFESLHHGELRIVRQSALDQLLERLTGQLYWRMRYRDDPRLPQVAHKAREYLHAHLHQDVGMDELALTCGVDRFRLSRAFKSAFGLPPHAYLVQLRLARARYLLAKGDQPADVAMALGFADQSHLGRWFMRAYGLTPAAYRKRCTNLPDR

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Crispr_ID: NC_017911_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017911_9

3358190-3358286

Orphan

Consensus_repeat	Method
TCGCAGGCAAGCCAGCTCCCACAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017911_9

>merge|NC_017911|9|3358190-3358286|CRISPRCasFinder
TCGCAGGCAAGCCAGCTCCCACAGTTGGATCGTTGGGGTGTCGGGTAGATAGGCGTCGGCTGGCGGGCCGCCTTCGCAGGCAAGCCAGCGCCCACAG

>NC_017911|9|8|3358190-3358286|CRISPRCasFinder
TCGCAGGCAAGCCAGCTCCCACAG	TTGGATCGTTGGGGTGTCGGGTAGATAGGCGTCGGCTGGCGGGCCGCCT
TCGCAGGCAAGCCAGCGCCCACAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017911.1\|WP_014718755.1\|3362914_3364081_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_017911.1\|WP_014718751.1\|3355989_3356481_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_017911.1\|WP_014718748.1\|3351106_3351268_+\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_019817194.1\|3368831_3369281_-\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_014718752.1\|3356646_3357753_-\|cell-division-protein-ZapE	unknown	unknown	gnl\|CDD\|224402
NC_017911.1\|WP_014718750.1\|3355675_3355888_+\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_014718757.1\|3364926_3365316_+\|DUF2946-domain-containing-protein	unknown	unknown	gnl\|CDD\|371400
NC_017911.1\|WP_014718744.1\|3347179_3347440_+\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_014718756.1\|3364395_3364833_-\|DUF3995-domain-containing-protein	unknown	unknown	gnl\|CDD\|372505
NC_017911.1\|WP_014718749.1\|3353296_3355534_+\|TonB-dependent-siderophore-receptor	unknown	unknown	gnl\|CDD\|227114
NC_017911.1\|WP_014718747.1\|3349848_3350832_-\|decarboxylating-6-phosphogluconate-dehydrogenase	unknown	unknown	gnl\|CDD\|236582
NC_017911.1\|WP_014718753.1\|3358293_3359745_-\|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl\|CDD\|273830
NC_017911.1\|WP_014718762.1\|3370062_3370293_+\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_014718754.1\|3359741_3362918_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NC_017911.1\|WP_032872432.1\|3369676_3369952_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368629
NC_017911.1\|WP_014718745.1\|3347507_3348332_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|369792
NC_017911.1\|WP_003190879.1\|3351425_3353168_+\|phosphoethanolamine-transferase-CptA	unknown	unknown	gnl\|CDD\|333729
NC_017911.1\|WP_014718758.1\|3365408_3367535_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657
NC_017911.1\|WP_014718746.1\|3348328_3349852_-\|glucose-6-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|237233
NC_017911.1\|WP_014718759.1\|3367692_3368700_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270359

Protein	Function_ID	Function_description	E-value
NC_017911.1\|WP_014718755.1\|3362914_3364081_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	1.14195e-78
NC_017911.1\|WP_014718751.1\|3355989_3356481_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.79332e-16
NC_017911.1\|WP_014718752.1\|3356646_3357753_-\|cell-division-protein-ZapE	gnl\|CDD\|224402	COG1485, COG1485, Predicted ATPase [General function prediction only].	4.22248e-139
NC_017911.1\|WP_014718757.1\|3364926_3365316_+\|DUF2946-domain-containing-protein	gnl\|CDD\|371400	pfam11162, DUF2946, Protein of unknown function (DUF2946). This family of proteins has no known function.	2.36346e-06
NC_017911.1\|WP_014718756.1\|3364395_3364833_-\|DUF3995-domain-containing-protein	gnl\|CDD\|372505	pfam13160, DUF3995, Protein of unknown function (DUF3995). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 138 and 149 amino acids in length. There are two completely conserved residues (W and P) that may be functionally important.	7.97696e-19
NC_017911.1\|WP_014718749.1\|3353296_3355534_+\|TonB-dependent-siderophore-receptor	gnl\|CDD\|227114	COG4773, FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism].	0
NC_017911.1\|WP_014718747.1\|3349848_3350832_-\|decarboxylating-6-phosphogluconate-dehydrogenase	gnl\|CDD\|236582	PRK09599, PRK09599, NADP-dependent phosphogluconate dehydrogenase.	0
NC_017911.1\|WP_014718753.1\|3358293_3359745_-\|efflux-transporter-outer-membrane-subunit	gnl\|CDD\|273830	TIGR01845, Outer_membrane_protein_OprM, efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family. Members of this model comprise a subfamily of the Outer Membrane Factor (TCDB 1.B.17) porins. OMF proteins operate in conjunction with a primary transporter of the RND, MFS, ABC, or PET systems, and a MFP (membrane fusion protein) to tranport substrates across membranes. The complex thus formed allows transport (export) of various solutes (heavy metal cations; drugs, oligosaccharides, proteins, etc.) across the two envelopes of the Gram-negative bacterial cell envelope in a single energy-coupled step. Current data suggest that the OMF (and not the MFP) is largely responsible for the formation of both the trans-outer membrane and trans-periplasmic channels. The roles played by the MFP have yet to be determined. [Cellular processes, Detoxification, Transport and binding proteins, Porins].	3.44022e-72
NC_017911.1\|WP_014718754.1\|3359741_3362918_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NC_017911.1\|WP_032872432.1\|3369676_3369952_+\|hypothetical-protein	gnl\|CDD\|368629	pfam05826, Phospholip_A2_2, Phospholipase A2. This family consists of several phospholipase A2 like proteins mostly from insects.	0.00338206
NC_017911.1\|WP_014718745.1\|3347507_3348332_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	2.30209e-70
NC_017911.1\|WP_003190879.1\|3351425_3353168_+\|phosphoethanolamine-transferase-CptA	gnl\|CDD\|333729	NF012179, CptA, phosphoethanolamine transferase CptA.	0
NC_017911.1\|WP_014718758.1\|3365408_3367535_+\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	3.06055e-72
NC_017911.1\|WP_014718746.1\|3348328_3349852_-\|glucose-6-phosphate-dehydrogenase	gnl\|CDD\|237233	PRK12853, PRK12853, glucose-6-phosphate dehydrogenase.	0
NC_017911.1\|WP_014718759.1\|3367692_3368700_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270359	cd13641, PBP2_HisX_like, Substrate-binding domain of ABC-type histidine transporter involves in betaine and proline uptake; the type 2 periplasmic-binding protein fold. This subfamily is part of a high affinity multicomponent binding-protein-dependent transport system specific to certain quaternary ammonium compounds for osmoregulation. The periplasmic substrate-binding domain, which is often fused to the permease component of the ATP-binding cassette transporter complex, is involved in uptake of osmoprotectants (also termed compatible solutes) such as glycine betaine, proline betaine, choline, and carnitine. Many microorganisms accumulate these compatible solutes in response to high osmolarity to offset the loss of cell water. This domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	9.2145e-115

>NC_017911.1|WP_014718752.1|3356646_3357753_-|cell-division-protein-ZapE
MTFDSPLAAYQHAIAQPGFVADDAQRRAVQALQACHEALHQGRSSIAGVYLWGPVGRGKTWLMDQFYQSLRVPARRQHFHHFMAWVHQRLFQLTGTQDPLQALARELSQAVRVLCFDELFVNDIGDAIILGRLFQVMFEEGVVMVCTSNQPPDQLYADGFNRERFLPGIDALKQHMQVVAVDGGEDHRLHPGVGMQRYWVNQPEALAAVFRQLSQGQAVNSVAVSVGYRTIMTVQASDTVLWCRYADLCEQPLAAMDFMLLCDRFHAILLGDVPNLSAQKRPGRIARGTEDGAERVVAGDRELPQLSVHDDSVRRFIALVDECYDRKVPLFIDAAVPLHSLYTEGYLEFPFRRTLSRLQEMQLQRFAT
>NC_017911.1|WP_014718751.1|3355989_3356481_-|GNAT-family-N-acetyltransferase
MDTPDILVLQASYTNAVHADAIGLLLNSYAEDPMGGGHSLPADLLQQLPAELAKRPHAFSVLAFVGGEPAGLVNCFEGFSTFACRPLVNVHDVMVKEQFRGLGLSQKMLQKVEEIARQRGCCKITLEVLEGNALAQSAYRKFGFDDSVFDPAHGRMLFWHKPL
>NC_017911.1|WP_014718750.1|3355675_3355888_+|hypothetical-protein
MKMSTLILASLMTLTSAAAFAEGGAERSKEFYNNFSFIQEKTHGKAEQQVASADGKSVKSETVDQAQPNS
>NC_017911.1|WP_014718749.1|3353296_3355534_+|TonB-dependent-siderophore-receptor
MFAPFTRSMTFTLGLFSLALSPDSRADTDPDTAPAKALELGATTISADNLGATTEHTGAYTTGSMSTATRLNLSVKETPQSISVVTRQQMDDFNLNTLTDVLRQTTGVNVQHYDSDRVYYSARGYGISNFQVDGMLNTFGYMKTDADTIIYDRIEVVRGATGLTTGAGDPSATVNMVRKRPTAHWQAKTGISGASHDNYYSYVDVGGPLAFDGKLRGRSVLAYRDSQSFRDNYGLQRAVGYGILEGDLSDDTVLAVGFDYQDKQVQGTSWGTVPYWNSQGGKARLPRSTNMAAHWSSWPLTDKTTFATLDHRLGGDWHLKAAYTHRQSDTDGKVYYGGAGFPNPDRSGMTAWASHMRGTSRMEAIDLNLAGSYTLVGREHALMMGYGEAAQRDVSPFMRSDLPASYYPIQDWKHMGGIGKFTDQVTDLKGEHSKKQQKAGYLATRLSLTDRLHAVLGSRYGSWELESAEPKYDANDQLTASGKTSQTHNDMWTPYAGLLYDITPQYTVYASYTDIFKPQDYRDANKKYLEPVVGSNYEVGLKGSVLNERLNLAAAYFWSTQDNVAERDDSVPPNPVTGEEYYRSGGKGNKVNGFELEAAGEITPDWNLTAGYTYTHSVNGSDKRNNTSQPLNLVKISSAYRLPGAWRNLTVGGAVNWQSETYDFSNRPTGQRNSEGRPITTRAKITQQGYTVVNLMSRYQFDEQVSASVNVNNLFDKKYYERVGFYNGVYWGEPRSVTLALDWKL
>NC_017911.1|WP_003190879.1|3351425_3353168_+|phosphoethanolamine-transferase-CptA
MAMFKRSTTTAKGFDWAGLGWLFLFFWYFSGITQLLIQLTGTSGFSGFRQAFFMSALWLAPMLLFPRRTRLLAALIGVVLWACSMASLGYFFIYQQEFSQSVIFIMFESNISEAGEYATQYFAWWIVLAFIAHTAFAIFLWTRLRPVYLPRGQSIVAAIAIVLAVVGYPLVKQIATSETMELAIDRFETRIEPAVPWQMIVAYRRYTEQLDNMQGMLTSASKIPPLNNLKDSMAGQPSTLVLVIGESTNRQRMSLYGYPRNTTPELDKLRDQLAVFDNVITPRPYTIEALQQVLTFADEENPDLYLKTPSIVSVMKQAGYKTFWITNQQTMTKRNTMLTTFSEQADEQVYLNNNRNQNARQYDGDVLAPFSKALADTAERKFIVVHLLGTHMSYQYRYPPTFDKFTDRQGVPAGVSDAQLPTYNSYDNAVLYNDFVVSSLIKDYAKTDPNGFLLYLSDHGEDVFDSAGHDTLGRNEGKPTAPMYTIPFMAYASPKWRESHDWSFAGDLQRPYSSSQLIHTWADMAGLSFDELDHSKSLVSDSFKPRPLLIGNPYETKQKALIDFSLIKPKKADGAEVVAK
>NC_017911.1|WP_014718748.1|3351106_3351268_+|hypothetical-protein
MTRPPQTLYVTLRRDELRQLKDERDQLQQEVLRLRLHLQAQLDQPSDAKPALC
>NC_017911.1|WP_014718747.1|3349848_3350832_-|decarboxylating-6-phosphogluconate-dehydrogenase
MQLGIIGLGRMGGNIARRLMLNGHTTVVYDRNEAFVEALSEEGATGVADLKALVAGLQKPRAVWVMLPAGAPTEDTINALSELLEDGDVIIDGGNTNYKDDVRRGKALAEKGLHYVDVGTSGGVWGLERGYCMMIGGDTETVNRLDPIFKSLAPGLGNIPRTKDRSASADPRAEQGYIHAGPAGSGHFVKMIHNGIEYGMMQAFAEGFDILKTKNSENLPEDQRFDLNVGDIAEVWRRGSVVSSWLLDLTADALATDPKLDGYSGSVADSGEGRWTIEAAMEQAVPVPVLSTSLFARFRSRQQSTYGDKMLSAMRFGFGGHVETSKK
>NC_017911.1|WP_014718746.1|3348328_3349852_-|glucose-6-phosphate-dehydrogenase
MTANGKKPKAEPAPPTTLFLFGAHGDLVKRLLMPALYNLSRDGLLGDGLRIVGVDHNAISDADFAKKLEDFIRTEASSKVRGNAENALDPALWAQLAKGISYVEGDFLDDSTYADIASKIADSGTANAVFYLATAPRFFSEVVQRLGSAGLLNETDDGFRRVVIEKPFGSDLATAEALNACLLKVMSEKQIYRIDHYLGKETVQNILVSRFSNVLFEAFWNNHYIDHVQITAAETVGVETRGNFFEKTGTLRDMVPNHLFQLLAMVAMEPPAAFGADAVRGEKAKVVGAIRPWSLEDARANSVRGQYTAGEIAGKPLPGYREEANVAPDSSTETFVALKVMIDNWRWVGVPFYLRTGKRMSIRDTEIVICFKQAPYAQFRDTEVDELKPTYLKIQIQPNEGMWFDLLAKQPGPTLEMANIELGFDYKDFFEMQPSTGYETLIYDCMTGDQTLFQRADNIENGWRAVQPFLDAWKEDDGIQAYKAGEDGPAAADALLARDGRAWHSLG
>NC_017911.1|WP_014718745.1|3347507_3348332_-|Cof-type-HAD-IIB-family-hydrolase
MSDATIQPIRFVLSDVDGTLLHPDHSLSQRTADAIRAMREAGVLFSLASGRPPKAMRHLIETFGIDVPVAGFNGGTLVNPDGSILVAHHLPAEAALITLALFSAEPDVEVWVFADGDWLRRDPPGPMVQREADGLGYGPVVVESFEPYLDRVDKIVAASNNTQLLVELEAQLQPKVQGLAQVSRSQPVYLDVTAMLANKGEALKTLAEHLGVPLAQTAAIGDGGNDPAMFHVAGLSIAMGQAEETVKRQANVVTGSNVEDGAAEAFERFILAAR
>NC_017911.1|WP_014718744.1|3347179_3347440_+|hypothetical-protein
MNAPLRINEALLIADRAFQPFQCVAWHDGVGALSLSVIDRTNTRIGSKQLSCTAYTDPAQLENLLLQARAELDKDGHQLQSWAMPK
>NC_017911.1|WP_014718753.1|3358293_3359745_-|efflux-transporter-outer-membrane-subunit
MKQAYPAFLLSLTLLAGCGSVGPDYSAPVLPAAQRATSFGAPIAGLGPGEVEVQWWQVFDEPALSQLIQQALAANHDIGIAAARLDEAKALLRENRQGFLPSGGAALGYEHRQRSEVETPFGEQRSIETTRAAVDAAWEIDLFGRVRRSVEAAQAQAGSRQALLRSVQASVAATVAATWFELQGIEAEQAVVADISQSQRDSLGLVGQMVSVGAATEFDRLRAEALLRNVEAVAPDLERRRAKSTNALAVLLGQAPQGFKPPLARPGRETLNLRTLQVGDPAGLLARRADIAAAERTLAAATAQIGVETAGLYPDIQVQGSIGLLAGSLSALGDAGMQSNFIAPVIRWSLLDTGRVRARIAASEARTQAALIAYDQTVLRALQETDDAFQANRAAGNALGLRLLEAAANREAASFARERFAQGEGVYLDVLEAERADFTSRRALTAARTEQRLAVVGIYKALGGGWEVCEQAGQACQGATVLR
>NC_017911.1|WP_014718754.1|3359741_3362918_-|efflux-RND-transporter-permease-subunit
MSFPRFFIDRPIFAIVLSVLMMIGGIVAFFHLPLSEYPAVTPPTVQVTASYPGANPQVIAETVAAPLEQVITGVEGMLYMTSQSATDGRMILTATFAQGTNADMAQIQVQNRVSRALPRLPEEVQRLGVVTQKTSPDILMVVHLLSPDQRYDPLYISNYAYLQVRDELSRLPGINDVLVWGAGEYSMRLWLDPDLIAARGLTAGDVIAAVREQNVQVAAGSVGQAPDSTAAFQVTVNTLGRLTDEEQFGDIIIRTGDNGQVTRLRDVARIEMGADAYALRSLLDGEPAVALQIIQSPGANALDVAQSVRETMQRLQTNFPEGLVSRIAYDPTVFVRASLESVAITLMEAILLVVIVVVVFLRNWRASLIPLMAVPVSIIGTFAVMHLMGFSLNTLSLFGLVLSIGIVVDDAIVVVENVERHIENGEEPMQAARRAMGEVTGPIIAITSVLAAVFIPTAFLSGLQGEFYRQFALTIAISTILSAVNSLTLSPALAGLLLRPRHAALVHDPRSLRGRATRLLEVLGRPFQRAPQAYGNTVRKVVGRRGVALLAYGGLLALTWFGFNAVPAGFVPMQDKYYLVGIAQLPNAASLERTDAVVRQMSKIALDEPGVESVVAFPGLSVNGFVNVPNAAVMFVMLDPFKERTSPDMAAVAIAGRLQAKFASIPDGFLGVFPPPPVPGLGVTGGFKLQVEDRGGVGLEALVQQTQVLMTKATESGQVAGLMTSLDVNAPQLNVDIDRTQVKSQGVRLADVFESLQVYLGSLYVNDFNRFGRTYKVTAQADADHRMQAEAIGRLQVRNAAGDMLPLSAFVTVTPSSGPDRVIHYNGYPSADISGGAMPGVSSGQAVALMERLAQEVLPEGVTYEWTDLTYQQKLAGSSALFIFPLCVLLAYLILAAQYNSWLLPLAVLLIVPMCLLSAILGVWLVEGDNNVFVQIGLVVLVGLAAKNAILIVEFARSLEVEGASPLEAVIHACQLRLRPILMTSLAFIAGVVPLVFASGAGAEMRHAMGVAVFAGMLGVTLFGLFLTPVFYVVMRSLALRVQRQGASPKVQLKESAS
>NC_017911.1|WP_014718755.1|3362914_3364081_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MYTKPVSLITGVLAVALTLGGCSDNSPPAAAAKPPGVPVAQVVARAVTPFVEYTGSLTAIDQVQLRPRVSGYLQSVSVPEGQFVAKGSPLFVIDPRMFQAAVNAAKARLREAEANALLAQAEHGRAEQLYAKKVVARDRLDTAVASLNAGRAQVEAARAALDTAQLDLSYTRVTAPISGRIDRALVTEGNYVTRGETALTTIVSIDPLHVYFDVDERTYLHSLAATRQHAGAKGEQAAKVMVAMLNDTTYARAGRVDFLANSADRKTGTVRVRAVVENPDGRLTPGLFAKVKLDTGAAQPRVLIADHSIGTDQGRRYVLVVGEGDKTEYRPVELGPVVDGLRVIEQGLQPGERIVVKGLVRPGMQVTPLAASIEGKPLEAPLAVGGVQ
>NC_017911.1|WP_014718756.1|3364395_3364833_-|DUF3995-domain-containing-protein
MSFVIARWIVGVFTFISMVHLYWAAGGKLGSLAAIPQLPGEFASGPRPAFKPSALGTFLVAMGLVAIALLVCLRAGLYFSPVSHGALQWGISAIAVLMFARAIGDSELVGFFKKVGGSRFARLDTYFYSPLCLVLGAGLLVVAWT
>NC_017911.1|WP_014718757.1|3364926_3365316_+|DUF2946-domain-containing-protein
MKLARADRSLIAWMLYCCVLFNVFACSIGHGQRVGMQLNGISGQFCTVDPRTQAPLPSNSTDENLPTLSKAFGCPLCSTGGMGPALNSHLNVAVLPQPHAPPAAVVLAADIPARFTWPAANPRAPPALA
>NC_017911.1|WP_014718758.1|3365408_3367535_+|TonB-dependent-receptor
MKHLPLLAGLFGCLPVCASALELAPTTIDGEQSAEPGLALDQSSGMASRLGLSVRETPASVAIANRNDIERHGAKTFRDAANTLPGVNASAPPGFGGFVSYRGFTSSQITQMFNGINVATGLARPVDAWIYDRVELVGGPSSLINGAGSVGGSLNYVTKLANREEQAIEGQLSYGSYDTAGLAFGLNHALTEPGAEVQHYARLDVSRNTNHSYIDRDQRDAWSVAFSLLSDLTPNLSHTLALEYQDEHEDSPYWGTPVLNPKAGELKIDKHNRFNNYNVADGRYEQRTIWARSIIDYRINDSTTLKNTLYHLDSQRDYRNLETYQYNADNSAVNRSTAYQVRHQGEQNGNQFELRHDTSVFGLATTWSGGFEYKVNSTTNSPLNVPGKSTVDPNHYDPGHFYDIPGTQPGFVKDKTNQVTTKALFVENRLGLTDKLSLLTGLRYDAIDLDVTNHRTLTATNPRHFKRSWEPVTGRVGLTYQFIPSANVYVQYSTAVEQPNTTTQVFDVSTGKQWEIGSKFDYLEGRGSATVAAYKIERKDFAVTDPLDPTNSIPVGAQSSKGIELASSLHITPRLLAEGNFAWVDAQYDEFNEKIASGEVVSRKGNTPTNVPKRVGNLWLTYDFAEDWQGGVDARYVAQVYADNANTQTVPAYTLFGTFLRYKLDANTSVTGRVRNLTNEVYAEFAHVSPAYYLGSPRTFELAVHTKF
>NC_017911.1|WP_014718759.1|3367692_3368700_-|ABC-transporter-substrate-binding-protein
MKGLKSLLAMGLTTLSLSLPVSAAQAPVHFADLNWESGSLITEVLRFIVEKGYDLPTDTLPGTTITLETALAKNDIQVIGEEWAGRSPVWVKAQAEGKVAGLGDIVKGATEGWWVPEYVVKGDPSKGLKPLAPDLKSVQDLARYKDVFKDPESPGKGRFLNSPIGWTSEVVNKQKLKAYGLDDSYVNFRSGSGAALDAEIASSIRRGKPVLFYYWSPTPLMGRYKLIQLEEPPFDADAWKTLTDADNPNPKPTRSLASKLSIGVSTPFQQEHPQIAQFFEKVEFPIEPLNKALATMSEHHTPPREVAQAFLKEHPQVWKAWLTEDVAQKIEASLQ
>NC_017911.1|WP_019817194.1|3368831_3369281_-|hypothetical-protein
MHALFVLGDLRAKLVKQFQSRFVYVTEQTPEGIYIAEIDTETALVVDDKPRLELKVGDHFRAAVLPSREGGKFELRFRDIKLTVYGIGDYAFVSSNEGQGIVFKEGHSVMLVFAAHDQLQEGLTKTLKAVTGKAAKWRKGELVTFKASE
>NC_017911.1|WP_032872432.1|3369676_3369952_+|hypothetical-protein
MQRRQHDATSFHTRSPCPDEQQYYCLLNLNGYSNSVLYQVVPAGKNFFHILEVPSGKIKGFRSDHIKACELAKSLEAKLYASGGGIVSSPG
>NC_017911.1|WP_014718762.1|3370062_3370293_+|hypothetical-protein
MTEFDIGEFIIHGDAREVDGEFQAVIIMRAKPPLNKVTAHQVEKDRWFKTADAAAVAGKEAAKALKAAVDCGALNS

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Crispr_ID: NC_017911_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017911_10

4701535-4701630

Orphan

Consensus_repeat	Method
GATCGTGGGGTGTCAGGTAGATAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017911_10

>merge|NC_017911|10|4701535-4701630|CRISPRCasFinder
GATCGTGGGGTGTCAGGTAGATAGCCGTCGGCTGGCAAGCCGTCATCGCAGGCAAGCCAGCTCCCACAGTTGGATCGTGGGGTGTCAGGTAGATAG

>NC_017911|10|9|4701535-4701630|CRISPRCasFinder
GATCGTGGGGTGTCAGGTAGATAG	CCGTCGGCTGGCAAGCCGTCATCGCAGGCAAGCCAGCTCCCACAGTTG
GATCGTGGGGTGTCAGGTAGATAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017911.1\|WP_014719738.1\|4690622_4692152_+\|DUF4129-domain-containing-protein	unknown	unknown	gnl\|CDD\|379261
NC_017911.1\|WP_014719750.1\|4710223_4711693_-\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|236531
NC_017911.1\|WP_014719737.1\|4689655_4690636_+\|stage-II-sporulation-protein-M	unknown	unknown	gnl\|CDD\|224219
NC_017911.1\|WP_003193918.1\|4711682_4712417_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_017911.1\|WP_014719745.1\|4703508_4704834_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NC_017911.1\|WP_193385104.1\|4708214_4708493_-\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_014719741.1\|4694305_4695637_+\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NC_017911.1\|WP_003193903.1\|4696271_4696646_-\|hypothetical-protein	unknown	unknown	unknown
NC_017911.1\|WP_003193915.1\|4708501_4708843_-\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|367760
NC_017911.1\|WP_003193916.1\|4709170_4710100_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|377694
NC_017911.1\|WP_014719743.1\|4698408_4699350_-\|iron-sulfur-binding-ferredoxin-reductase	unknown	unknown	gnl\|CDD\|235575
NC_017911.1\|WP_014719746.1\|4705103_4706423_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340925
NC_017911.1\|WP_003193904.1\|4696819_4698271_+\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
NC_017911.1\|WP_014719748.1\|4707456_4708089_+\|flavin-reductase-family-protein	unknown	unknown	gnl\|CDD\|224766
NC_017911.1\|WP_014719742.1\|4695689_4696049_-\|PilZ-domain-containing-protein	unknown	unknown	gnl\|CDD\|377796
NC_017911.1\|WP_014719739.1\|4692148_4693306_+\|DUF4350-domain-containing-protein	unknown	unknown	gnl\|CDD\|379527
NC_017911.1\|WP_014719747.1\|4706523_4707279_-\|membrane-protein	unknown	unknown	gnl\|CDD\|227049
NC_017911.1\|WP_003193907.1\|4699566_4701090_+\|fumarate-hydratase	unknown	unknown	gnl\|CDD\|224862
NC_017911.1\|WP_014719740.1\|4693302_4694298_+\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NC_017911.1\|WP_014719744.1\|4701748_4703515_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226654

Protein	Function_ID	Function_description	E-value
NC_017911.1\|WP_014719738.1\|4690622_4692152_+\|DUF4129-domain-containing-protein	gnl\|CDD\|379261	pfam13559, DUF4129, Domain of unknown function (DUF4129). This presumed domain is found at the C-terminus of proteins that contain a transglutaminase core domain. The function of this domain is unknown. The domain has a conserved TXXE motif.	5.23818e-05
NC_017911.1\|WP_014719750.1\|4710223_4711693_-\|HAMP-domain-containing-protein	gnl\|CDD\|236531	PRK09467, envZ, osmolarity sensor protein; Provisional.	1.52353e-46
NC_017911.1\|WP_014719737.1\|4689655_4690636_+\|stage-II-sporulation-protein-M	gnl\|CDD\|224219	COG1300, SpoIIM, Uncharacterized membrane protein [Function unknown].	1.47292e-45
NC_017911.1\|WP_003193918.1\|4711682_4712417_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.01209e-80
NC_017911.1\|WP_014719745.1\|4703508_4704834_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	0
NC_017911.1\|WP_014719741.1\|4694305_4695637_+\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	4.83555e-67
NC_017911.1\|WP_003193915.1\|4708501_4708843_-\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|367760	pfam03992, ABM, Antibiotic biosynthesis monooxygenase. This domain is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species. It's occurrence as a repeat in Streptomyces coelicolor SCO1909 is suggestive that the other proteins function as multimers. There is also a conserved histidine which is likely to be an active site residue.	7.55553e-11
NC_017911.1\|WP_003193916.1\|4709170_4710100_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|377694	pfam06719, AraC_N, AraC-type transcriptional regulator N-terminus. This family represents the N-terminus of bacterial ARAC-type transcriptional regulators. In E. coli, these regulate the L-arabinose operon through sensing the presence of arabinose, and when the sugar is present, transmitting this information from the arabinose-binding domains to the protein's DNA-binding domains. This family might represent the N-terminal arm of the protein, which binds to the C-terminal DNA binding domains to hold them in a state where the protein prefers to loop and remain non-activating. All family members contain the pfam00165 domain.	3.48757e-57
NC_017911.1\|WP_014719743.1\|4698408_4699350_-\|iron-sulfur-binding-ferredoxin-reductase	gnl\|CDD\|235575	PRK05713, PRK05713, iron-sulfur-binding ferredoxin reductase.	0
NC_017911.1\|WP_014719746.1\|4705103_4706423_+\|MFS-transporter	gnl\|CDD\|340925	cd17367, MFS_KgtP, Alpha-ketoglutarate permease of the Major Facilitator Superfamily of transporters. This subfamily includes Escherichia coli alpha-ketoglutarate permease (KgtP) and similar proteins. KgtP is a constitutively expressed proton symporter that functions in the uptake of alpha-ketoglutarate across the boundary membrane. Also included is a putative transporter from Pseudomonas aeruginosa named dicarboxylic acid transporter PcaT. The KgtP subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	0
NC_017911.1\|WP_003193904.1\|4696819_4698271_+\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
NC_017911.1\|WP_014719748.1\|4707456_4708089_+\|flavin-reductase-family-protein	gnl\|CDD\|224766	COG1853, COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only].	1.97597e-40
NC_017911.1\|WP_014719742.1\|4695689_4696049_-\|PilZ-domain-containing-protein	gnl\|CDD\|377796	pfam07238, PilZ, PilZ domain. PilZ is a c-di-GMP binding domain which is found C terminal to pfam07317. Proteins which contain PilZ are known to interact with the flagellar switch-complex proteins FliG and FliM. This interaction results in a reduction of torque generation and induces CCW motor bias. This domain forms a beta barrel structure.	0.000107143
NC_017911.1\|WP_014719739.1\|4692148_4693306_+\|DUF4350-domain-containing-protein	gnl\|CDD\|379527	pfam14258, DUF4350, Domain of unknown function (DUF4350). This domain family is found in bacteria, archaea and eukaryotes, and is approximately 70 amino acids in length.	9.18509e-08
NC_017911.1\|WP_014719747.1\|4706523_4707279_-\|membrane-protein	gnl\|CDD\|227049	COG4705, COG4705, Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown].	9.38415e-92
NC_017911.1\|WP_003193907.1\|4699566_4701090_+\|fumarate-hydratase	gnl\|CDD\|224862	COG1951, TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion].	8.39593e-145
NC_017911.1\|WP_014719740.1\|4693302_4694298_+\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	3.16392e-95
NC_017911.1\|WP_014719744.1\|4701748_4703515_+\|sensor-histidine-kinase	gnl\|CDD\|226654	COG4191, COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms].	0

>NC_017911.1|WP_003193907.1|4699566_4701090_+|fumarate-hydratase
MTVIKQDDLIQSVADALQFISYYHPVDFIQAMHEAYLREESPAARDSIAQILINSRMCATGHRPICQDTGIVTVFVRVGMDVRWDGATMGLDDMINEGVRRAYNLPENVLRASILADPAGARKNTKDNTPAVIHYSIVPGNTVEVDVAAKGGGSENKSKMAMLNPSDSIVDWVLKTVPTMGAGWCPPGMLGIGIGGTAEKAAVMAKEVLMESIDIHELKKRGPQNRIEEMRLELFEKVNQLGIGAQGLGGLTTVLDVKIMDYPTHAASLPVCMIPNCAATRHAHFVLDGSGPASLEAPPLDAYPEIVWEAGPSARRVNLDTLTPEEVQSWKPGETVLLNGKMLTGRDAAHKRMVEMLNKGETLPVDLKGRFIYYVGPVDPVREEVVGPAGPTTATRMDKFTRQILEQTGLLGMIGKSERGPTAIEAIKDHKAVYLMAVGGAAYLVAQAIKKSRVVAFAELGMEAIYEFDVKDMPVTVAVDSKGESVHITGPAIWQKKISDSLAVEVQ
>NC_017911.1|WP_014719743.1|4698408_4699350_-|iron-sulfur-binding-ferredoxin-reductase
MPELYVGKRHWSVTPGSNLLDALNQAGVAVPFSCRAGSCHACLVRCEGEVDDQQPEALSPTQRQQGWRLACQCRVIADLKVDAFDPQRDGLPAQVVGADWLSSTVLRLRLQPERALRYRAGQHLVLWAGQVARPYSLASLPQEEPYLEFHIDCRQPGAFSDAARQLKVGDPVCLGELRGGALHYDPDWQSRPLWLLASGTGLGPLWGVLREALRQDHQGEIRVIHLAHEAEAHYLAEPLAALAAQHGHLTVELWTAAQLQPALAQLRLVSRHTLALLCGHPASVEAFSKRLFLAGLPRNQLLADVFLARPFTL
>NC_017911.1|WP_003193904.1|4696819_4698271_+|pyruvate-kinase
MSVRRTKIVATLGPASNSPEVLEQLILAGLDVARLNFSHGTPDEHKARAKLVRDLAAKHGRFVALLGDLQGPKIRIAKFTNKRIELKIGDKFTFSTSHPLTEGTQDVVGIDYPDLVKDCGVGDELLLDDGRVVMRVDTATPTELNCTVIIGGPLSDHKGINRRGGGLTAPALTEKDKADIKLAAEMEVDYLAVSFPRDAADMEYARKLRDEAGGTAWLVAKIERAEAVADDETLDGLIKASDAVMVARGDLGVEIGDAELIGIQKKIILHARRHNKAVIVATQMMESMIQNPMPTRAEVSDVANAVLDYTDAVMLSAESAAGPYPLEAVQAMARICVGAEKHPTSKTSSHRIGKVFESCDQSIALAAMYTANHFPGVKAIIALTESGYTPLIMSRIRSSVPIYAFTPHREAQARAAMFRGVYTIPFDPASLAPNEVSQKAIDELVKRGVVEKGDWVILTKGDSYHTTGGTNGMKILHVGDPQV
>NC_017911.1|WP_003193903.1|4696271_4696646_-|hypothetical-protein
MRILLVAALAVSVVGCTRWSMDHHLNNAYRAYGVGDCQRVTLELSQVDRESRTRRYVQPEVSMLRGQCLERQKLFVDAAQTYQFIIGHYPSSEYAYRARARLDTLQQLGHLPAAGLAKPRPASL
>NC_017911.1|WP_014719742.1|4695689_4696049_-|PilZ-domain-containing-protein
MFTERRIERHQLPYFLQVFNRITDKPIGYLGNVSENGLMLISSLPMMTEVDFELRLKVPVAQGEFKAIDLTATCLWSHEDVTPQHYDSGFSVLEAPKEYRHLINALLQYFSFYPLQASV
>NC_017911.1|WP_014719741.1|4694305_4695637_+|DUF58-domain-containing-protein
MKPTRLLLTWLGVLLGLNILLGASAALQFKVPATLHSVAWGLLLALLLLAMLDAARLRRRPSVRVYRTLPGSLALGRWEEIRLCLEHDYPQPLTVQVFDHVPDGLAVENLPQFIQLRPGERAELGYRVRPLRRGHFHFSRCELLLPSPLGLWSARRWVDTRDSTRVYPDFARLYGAQLRGVDNWLSQLGVRQHQRRGLGLEFHQLREFREGDSLRQIDWKATARQRTPIAREYQDERDQQIVFMLDCGQHMRSQDDELSHFDHALNACLLLSYVALRQGDAVGLCTFASDQPRYLKPVKGSGQLNLLLNAVYDLQTTRKTADYQAAASQLLARQKRRALVIIVTNLRDEEDEALMAAVQRIGRHHRVLVASLREEVLDQLRQTPVQTLPEALAYSGTIDYLNTRNQRHDRLSAHGLSVLDTLPSALGAGLVTRYLEWKKAGVF
>NC_017911.1|WP_014719740.1|4693302_4694298_+|MoxR-family-ATPase
MSDSPLATALTAENLQQASQQAQALRVELRKAVIGQDPVIDDVLTALIAGGHVLLEGVPGLGKTLLVRALARCFGGDFARIQFTPDLMPSDVTGHAVYDLQTEQFKLRKGPLFTHLLLADEINRAPAKTQAALLEAMQERQVTLEGEALPIGQPFMVLATQNPIEQEGTYPLPEAELDRFMLKVRMDYPDALQELDMVREVTRSSKADMLEVQPLRTVLQAEDVVRMQQIASDLPLDEQVLDYAVRLARATRSWPGLAIGAGPRASIALVRGARARALLRGGEFVTPDDIKGCALAVLRHRVRIAPELDIDGLEVDQVLQQLLDQIAAPRQ
>NC_017911.1|WP_014719739.1|4692148_4693306_+|DUF4350-domain-containing-protein
MNRALLWTALLLACLVGAGGLYAWHKAIPYEEVVDRGPSPEARANPYLAAEHFLRQHGLVVAHAKGLERLAELPAKGHSLLLLGERSNMTPRQVDQLLGWAKAGGHLLLVAEALWDEEAGTSGDLLLDRLTIRQTLSDTFDEPVPPRKKTKPDLTKLYVDNETAPAYFSFDTYFNLTDPKHLAQFSANSAQSSHLMQLDLGQGRVTVITDSDLWKTTDIGNHDNAWLLWYLNQGTDVTLLFNSDTDDLFTLLLRYFPQALVALVALLALGLWQAGMRQGPIQTPAPKARRQLQEHLQASADFLLRRSGQGTLLQALRHDILRAARRRHPGFEHLDASEQRQVLEHLTRQPPHIISQALEPVALKRLSSADFSRQVAHLQTLRNAL
>NC_017911.1|WP_014719738.1|4690622_4692152_+|DUF4129-domain-containing-protein
MRLTDASVVIRPRTSWEAMDLGVLMAREHRVLLMGSWALVSLPVFSLLTVLLWNYPSLVMFLFWWLKPAFDRLPLYILSKALFGEPPSLKQAVRQWPQLLKGQLFASLTWRRLSMSRSFTLPVSQLEGLDGDARQRRLGVLLQRNAGAARWLTTIGVHMEIGLWFGGMTLFYLFIPQQVELDWDWQRLIFASASDVLWLEHLSNAFYALVLVFWEPIYVACGFSLYLNRRTVLEAWDLELVFRRLRQRLSNVAPLLLLVVGLALLHISPPTMADETTAHKPLSAQAASQSIQALLEKPPFKNPETVTRYRFGEEKAPVKNKATGDGKLPGWLQALLDNLNSDTFKYVAKTLEILLWSLVIGGLALVCWRYREWLRTFVSRLGPTRTAAPSPVPAQLFGLELGTETLPEDIASTAEQLWPTHPREALGLLYRGLLSRLLHEFDLPLTSADTEGQVLERVHHLQQPQLLAFSDELTRHWQNLAYGHRLPPSSAQQKLCSDWRALFSDGAGQ
>NC_017911.1|WP_014719737.1|4689655_4690636_+|stage-II-sporulation-protein-M
MKQSLFESRHQRQWHTFAEQLTQLEQGKAKAADVADFPHQYRRLCQHLALAQQRGYSSYLVDTLQQLALRGHQQLYRHRSQLTANILAFLLAEFPRLVREQWRFVLIAGLLFFGSLVGIALLVYRFPDLIYSIISPQQVADMQGMYNPDASRLGRAAERAASEDWMMFGYYVMHNIGIAFQTFAAGLLFGLGSVFFLIFNGLVIGAVSGHLTDIGYGQTFWSFVIGHGAFELSAITLAGAAGLQLGWSLVAPGRLARSEALRLAARKSVRMLCGVMVFLLIAAFIEAYWSSTTRIEPWIKYAVGAALWLLVAAYLSLAGRSRHAPD
>NC_017911.1|WP_014719744.1|4701748_4703515_+|sensor-histidine-kinase
MIVIPRPLRLTFYSLLIIAGAVLAAALATRHAERQALVDDAARANQQLALYANSLHTLIERYRALPAVLALDSEMISALKGPLDATTQDRLNRKLERINGAAQSSTLELMDRTGLAVAASNWNLPSSYVGHNYAFRPYFSQTLSQGTGRFYAVGVTTGIPGYFLSSAVVDEHEQFLGAMVVKLEFPELEREWAQGNDLLLVSDARGIVFIANQPGWRYRNLRPLSENDLAELKTTRQYDKKQLQPLDTQPLQRFDENSHLIRVNGPDGNANYIWESLPLKREGWTLHLLRKPQFAFEDQRNAGLAAAGSWLALVFLVLFLSQRWRLARLRQRSREELEQLVEERTQALRTAQDGLVQSAKLAALGQMSAALAHEINQPLTAQRMQLATLRLLLDHGRVDDAYKALTPLDDMLTRMAALTGHLKTFARKSPSGLREKLDLATVVDQSLHLLDARLRDEAIGVVLDLTRPAWVRGDAIRLEQVLINLLRNALDAMADKPRKRLEIRLHADQQLWQLSVCDSGGGIAEEHLSSVFDPFFTTKPVGDGLGLGLAVSYAIVHELGGRLSAANRGDGATFTLTLPIALETPDLC
>NC_017911.1|WP_014719745.1|4703508_4704834_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MLNAVIVVDDEASIRTAVEQWLSLSGFDVQLFSRAEECLAQLPKDFAGVILSDVRMPGLSGLELLAEVQRRDADLPVILLTGHGDVPMAVEAMRDGAYDFLEKPFSPDALLNSLRRALDKRGLILENRRLHQQADHRAQLESSLLGVSKGLQSLRRQVLDLASLPVNVLIRGETGSGKELVARCLHDFGPRAKKPFVALNCAAIPEQLFEAELFGHESGAFTGAHGKRIGKLEYAHGGTLFLDEIESMPLAQQVKLLRVLQEQKLERLGSNQSIQVDLRIIAATKPDLLEEARAGRFREDLAYRLNVAQLRLPPLRERREDIPLLYEHFAQSAAERLGRQVEPLSGPQLGRLLSHDWPGNVRELANVAERQVLGLDEPEPQGIEAGQSLAAQQEAFEAHCLKAALTRHKGDIKAVLAELQLPRRTFNEKMQRHGLVREMFV
>NC_017911.1|WP_014719746.1|4705103_4706423_+|MFS-transporter
MDNSNTVPLGSTAAKAQERTTSSRIKSIFSGSVGNMVEWYDWYVYAAFSLYFAKAFFPKGDTTAQLLNTAAIFAVGFLMRPIGGWLMGLYADKVGRKKALMASVYLMCFGSLLIALSPGYEIIGIGAPILLVFARLLQGLSVGGEYGTSATYLSEMATKERRGFYSSFQYVTLISGQLIALAVLIVLQQVLTTEQLYAWGWRIPFAIGALCAVVALYLRRGMEETESFTKKEKAKESAMRTLMRHPKELMTVVGLTMGGTLAFYTYTTYMQKYLVNTVGMSISDSTTISAATLFLFMCLQPIIGGLSDKIGRRPILIAFGVLGTLFTVPILTTLHTIQSWWGAFFLIMAALIIVSGYTSINAVVKAELFPTEIRALGVGLPYALTVSIFGGTAEYIALWFKSIGMETGYYWYVTACIAVSLMVYVTMKDTRKHSRITTD
>NC_017911.1|WP_014719747.1|4706523_4707279_-|membrane-protein
MNKLPQITLAFWVMKICATTLGETAGDLLSMTLNIGYAISSMILISVFLVTLVTQLWSKTYNPVLYWIVILSTSTAGTTMSDFMDRTLGLGYATGSMILIVILMIIFALWHLSGDSLNVNKVQTFRGELFYWMAILFSNTLGTALGDFLADDSGLGFAGGALLIGSTIAAVVVLKYFTRISSVLLFWVAFVLTRPFGATLGDFLTKPHEKGGLDFGTIGSSAVLAAVLVVMIAGASYAQRRYGRNEAAELS
>NC_017911.1|WP_014719748.1|4707456_4708089_+|flavin-reductase-family-protein
MPDDIHFYEPANGHGLPHDPFNAIVGPRPIGWISSHDREGRLNLAPYSFFNAFNYIPPIIGFSSVGRKDSLNNIEQTGEFVWNLATRPLAEQMNQSCAAVSPEVNEFELSGLTPVASKIVGVPRVGESPVSFECKVTQIIQLQRADQQLVPSWLVLGEVVAVHIAKWLLKDGIYDTAAAEPILRGGGPADYFQLGPEALFKMYRPGATKP
>NC_017911.1|WP_193385104.1|4708214_4708493_-|hypothetical-protein
MADFPLARTCNMARKQFAHHEAVSAVVPGEGGYSAAVAVKVLDGMGAPRFHKILDGQTFKTASDADDAATLQLEHLVDVDAEGQLTWATAER
>NC_017911.1|WP_003193915.1|4708501_4708843_-|antibiotic-biosynthesis-monooxygenase
MSTPIPASHMAFIRARSGCSTELGARLSSLIEPGRQAQGCLQFSLQHSQVDPDVWLVSGFWSSEQAMSAYFNSPALMIFTELLNDMVVRSMDFQTFTDASAAQAYGEYLQLAG
>NC_017911.1|WP_003193916.1|4709170_4710100_+|AraC-family-transcriptional-regulator
MPSPESKPVPLDAEMEKQRAELASIVHRHTWEDGSYGTAITSLYLNRHNAPRDFMPVLVEPALCILASGSKEVRLADEIFAYDPLNYLVFSVAMPVAGRIIDATAEDPNLSVRINIDPAQLTALIAEAGPMGVPSRPTSRGMYVDRIDHALLDAVLRLTRLLDTPKDIAMLAPLINREILYRLLRGPQGYRLYEIAVANSQSHRVSQAITWLNGNYEQPLRIDDLAKEVNLSVSTLHHRFKAITAMSPLQYQKQLRLQEARRLMIAEGLEASAAGYRVGYESPSQFSREYSRLFGAPPLRDLARLRQSI
>NC_017911.1|WP_014719750.1|4710223_4711693_-|HAMP-domain-containing-protein
MPTEALNERRRRFPVPRSLLGRMLLLTLLAVLFAQALSSVIWVSQLRATQLEGLVTSARSLAHSMTASVSYFRSLPVAYRPLVLDQLRSMGGTRFVVTLNDRPLDMQLLPETPRKQAVLVAVDEVLRQTLGADVHISVEFVSAEDLRIFNAGLKLDELPRSWAHYALTLEPVNPPVLVTQIQLAPGEWLYIASLLPEPYTSLEEQGLPSQQVWFIVLTSGFLLLFIGLLVHWQSRPLKRLARAARDMSLGADVEPVAEGGGSEVVEVGRAFNAMRERISRYLTERSQLFSAISHDLRTPITRLRLRVELLEDENLQNKFGRDLDELELLVKGALQCVKDTDIHENIQPVDLNHVLECLVEPYLAPHGNGRVTLDGAALSAYPGKPLALKRCIGNLIDNALKYGQNAHLHIEDDGAQFILHVDDEGPGVPQQRLEQVFEPHFRLAGQQQGYGLGLGIARNIAHSHGGEVSLQNLREGGLRVTLQLPRTLD
>NC_017911.1|WP_003193918.1|4711682_4712417_-|response-regulator-transcription-factor
MSVISKSILLVDDDQEIRELLQTYLSRAGFQVRGVSDGAGFRQAMNEAPCDLVILDVMLPDEDGFSLCRWIRQHPRQAQVPIIMLTASSDEADRVIGLELGADDYIGKPFSPRELQARIKALLRRCQFGQERSSGGDVWVFDEWRLDMISHRLFHVDGEEVILSGADFALLKLFLDHPQQILDRDTIGNATRGRDLMPLDRIVDMAVSRLRQRLRDTEKPPRLIRTVRGSGYQLAASVVAGNAH

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017911_1	1.3\|739163\|33\|NC_017911\|CRT	739163-739195	33	MN536027	Pseudomonas phage vB_Pae-SS2019XII, complete genome	15255-15287	7	0.788
NC_017911_1	1.6\|739313\|30\|NC_017911\|CRT	739313-739342	30	MT723933	Streptomyces phage Keanu, complete genome	72838-72867	7	0.767
NC_017911_1	1.6\|739313\|30\|NC_017911\|CRT	739313-739342	30	MN096355	Mycobacterium phage Purky, complete genome	12045-12074	7	0.767
NC_017911_1	1.6\|739313\|30\|NC_017911\|CRT	739313-739342	30	AP014194	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C71-MedDCM-OCT-S28-C33, * SEQUENCING IN PROGRESS *	18820-18849	7	0.767
NC_017911_1	1.6\|739313\|30\|NC_017911\|CRT	739313-739342	30	MN693867	Marine virus AFVG_250M804, complete genome	26980-27009	8	0.733
NC_017911_1	1.3\|739163\|33\|NC_017911\|CRT	739163-739195	33	MG030346	Proteus phage PM87, complete genome	26416-26448	9	0.727
NC_017911_1	1.3\|739163\|33\|NC_017911\|CRT	739163-739195	33	CP059058	Proteus phage ASh-2020a, complete genome	47889-47921	9	0.727
NC_017911_1	1.3\|739163\|33\|NC_017911\|CRT	739163-739195	33	MN840486	Proteus phage P16-2532, complete genome	26320-26352	9	0.727
NC_017911_1	1.3\|739163\|33\|NC_017911\|CRT	739163-739195	33	NC_011961	Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence	526340-526372	10	0.697
NC_017911_1	1.6\|739313\|30\|NC_017911\|CRT	739313-739342	30	MT521992	Rhodococcus phage NiceHouse, complete genome	69380-69409	10	0.667
NC_017911_1	1.3\|739163\|33\|NC_017911\|CRT	739163-739195	33	MN184886	Erwinia phage pEp_SNUABM_08, complete genome	32222-32254	11	0.667

1. spacer 1.3|739163|33|NC_017911|CRT matches to MN536027 (Pseudomonas phage vB_Pae-SS2019XII, complete genome) position: , mismatch: 7, identity: 0.788

accagtaccaccgccagtgccgccaccagtacc	CRISPR spacer
gccccccccaccgccagtgccgccagcagcacc	Protospacer
.**  . ****************** ***.***

2. spacer 1.6|739313|30|NC_017911|CRT matches to MT723933 (Streptomyces phage Keanu, complete genome) position: , mismatch: 7, identity: 0.767

cgtgccaccaccggttccaccgccagtgcc	CRISPR spacer
gtcgccaccaccggttgcaccgccagcacg	Protospacer
  .************* *********..*

3. spacer 1.6|739313|30|NC_017911|CRT matches to MN096355 (Mycobacterium phage Purky, complete genome) position: , mismatch: 7, identity: 0.767

cgtgccaccaccggttccaccgccagtgcc	CRISPR spacer
tcagccaccaccggcgccaccgccagcacc	Protospacer
.  ***********. **********..**

4. spacer 1.6|739313|30|NC_017911|CRT matches to AP014194 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C71-MedDCM-OCT-S28-C33, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.767

cgtgccaccaccggttccaccgccagtgcc	CRISPR spacer
actgccaccaccgctgccaccgccaccacc	Protospacer
  *********** * ********* ..**

5. spacer 1.6|739313|30|NC_017911|CRT matches to MN693867 (Marine virus AFVG_250M804, complete genome) position: , mismatch: 8, identity: 0.733

cgtgccaccaccggttccaccgccagtgcc	CRISPR spacer
ccaaccaccaccgcctccaccgccagtatt	Protospacer
*  .********* .************...

6. spacer 1.3|739163|33|NC_017911|CRT matches to MG030346 (Proteus phage PM87, complete genome) position: , mismatch: 9, identity: 0.727

accagtaccaccgccagtgccgccaccagtacc	CRISPR spacer
gttagtaccaccgccagttccgccaccgccagt	Protospacer
...*************** ********. .* .

7. spacer 1.3|739163|33|NC_017911|CRT matches to CP059058 (Proteus phage ASh-2020a, complete genome) position: , mismatch: 9, identity: 0.727

accagtaccaccgccagtgccgccaccagtacc	CRISPR spacer
gttagtaccaccgccagttccgccaccgccagt	Protospacer
...*************** ********. .* .

8. spacer 1.3|739163|33|NC_017911|CRT matches to MN840486 (Proteus phage P16-2532, complete genome) position: , mismatch: 9, identity: 0.727

accagtaccaccgccagtgccgccaccagtacc	CRISPR spacer
gttagtaccaccgccagttccgccaccgccagt	Protospacer
...*************** ********. .* .

9. spacer 1.3|739163|33|NC_017911|CRT matches to NC_011961 (Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

accagtaccaccgccagtgccgccaccagtacc	CRISPR spacer
accaggagcaccgccagtgccgccgcagccgag	Protospacer
***** * ****************.* . ..

10. spacer 1.6|739313|30|NC_017911|CRT matches to MT521992 (Rhodococcus phage NiceHouse, complete genome) position: , mismatch: 10, identity: 0.667

cgtgccaccaccggttccaccgccagtgcc	CRISPR spacer
tcggccaccaccgattccaccgccgagctg	Protospacer
.  **********.**********..  .

11. spacer 1.3|739163|33|NC_017911|CRT matches to MN184886 (Erwinia phage pEp_SNUABM_08, complete genome) position: , mismatch: 11, identity: 0.667

accagtaccaccgccagtgccgccaccagtacc	CRISPR spacer
tgggttaccaccgccagttccgccgccagggtt	Protospacer
   . ************* *****.**** ...

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1278295 : 1363531

uncultured_Caudovirales_phage(22.58%)

tRNA,tail,holin,plate

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014717137.1\|1278295_1278766_+\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
WP_014717138.1\|1278899_1280009_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.8e-23	30.9
WP_014717139.1\|1280005_1280926_-	ornithine carbamoyltransferase	A0A1J0F9B8	Only_Syngen_Nebraska_virus	7.1e-19	27.4
WP_014717140.1\|1281359_1283468_+	molybdopterin oxidoreductase family protein	NA	NA	NA	NA
WP_014717141.1\|1283545_1283884_+	Grx4 family monothiol glutaredoxin	NA	NA	NA	NA
WP_012722487.1\|1283952_1284423_-	bacterioferritin	NA	NA	NA	NA
WP_003188977.1\|1284624_1284843_-	bacterioferritin-associated ferredoxin	NA	NA	NA	NA
WP_003172097.1\|1285086_1285689_+	peroxiredoxin	NA	NA	NA	NA
WP_003188980.1\|1285753_1286425_-	ribonuclease T	NA	NA	NA	NA
WP_014717142.1\|1286421_1287468_-	dihydroorotase	NA	NA	NA	NA
WP_014717143.1\|1287624_1288533_+	OmpA family protein	NA	NA	NA	NA
WP_003188984.1\|1288661_1289879_+	argininosuccinate synthase	NA	NA	NA	NA
WP_003188986.1\|1290487_1291120_+	response regulator transcription factor	NA	NA	NA	NA
WP_014717144.1\|1291203_1291386_-	hypothetical protein	NA	NA	NA	NA
WP_003188989.1\|1291493_1292132_-	endonuclease III	NA	NA	NA	NA
WP_014717145.1\|1292192_1293161_-	electron transport complex subunit RsxB	NA	NA	NA	NA
WP_014717146.1\|1293248_1295300_-\|tRNA	methionine--tRNA ligase	NA	NA	NA	NA
WP_014717147.1\|1295473_1296568_+	iron-sulfur cluster carrier protein ApbC	NA	NA	NA	NA
WP_014717148.1\|1297090_1297414_-	ferredoxin family protein	NA	NA	NA	NA
WP_014717149.1\|1297556_1300148_-	DNA mismatch repair protein MutS	A0A1V0SJ67	Klosneuvirus	3.0e-30	22.0
WP_080643468.1\|1300362_1300563_-	DUF3077 domain-containing protein	NA	NA	NA	NA
WP_014717151.1\|1301016_1303704_+	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
WP_014717152.1\|1303768_1304824_+	hydroxyacid dehydrogenase	M1NSB9	Streptococcus_phage	5.7e-20	32.5
WP_014717153.1\|1304851_1305505_+	RraA family protein	NA	NA	NA	NA
WP_014717155.1\|1305801_1306173_-	hypothetical protein	NA	NA	NA	NA
WP_014717156.1\|1306165_1306654_-	DUF4065 domain-containing protein	D0UIM3	Aggregatibacter_phage	3.8e-27	44.5
WP_172832690.1\|1306879_1307623_+	helix-turn-helix transcriptional regulator	B5TK58	Pseudomonas_phage	5.8e-120	87.4
WP_005785384.1\|1308212_1308551_+\|holin	pyocin R2, holin	B5TK61	Pseudomonas_phage	1.4e-44	85.4
WP_014717158.1\|1308574_1309090_+	hypothetical protein	NA	NA	NA	NA
WP_014717159.1\|1309093_1309705_+\|plate	phage baseplate assembly protein V	A0A2H4JBW8	uncultured_Caudovirales_phage	3.8e-45	53.8
WP_014717160.1\|1309714_1310047_+\|plate	phage baseplate protein	A0A2H4JI46	uncultured_Caudovirales_phage	5.1e-36	67.3
WP_014717161.1\|1310043_1311039_+\|plate	baseplate J/gp47 family protein	A0A2H4JC04	uncultured_Caudovirales_phage	3.2e-113	64.4
WP_014717162.1\|1311035_1311674_+\|tail	phage tail protein I	A0A2H4JDK0	uncultured_Caudovirales_phage	4.8e-38	51.9
WP_014717163.1\|1311670_1312201_+\|tail	tail fiber protein	B0ZSG1	Halomonas_phage	3.2e-48	56.2
WP_020301162.1\|1312254_1313007_+	hypothetical protein	NA	NA	NA	NA
WP_014717165.1\|1313016_1313253_+\|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_003189022.1\|1313341_1313515_+	hypothetical protein	NA	NA	NA	NA
WP_014717166.1\|1313517_1314684_+\|tail	tail protein	B0ZSG8	Halomonas_phage	7.2e-125	57.0
WP_014717167.1\|1314683_1315190_+\|tail	phage major tail tube protein	Q6R4W3	Vibrio_virus	2.2e-22	34.5
WP_014717168.1\|1315370_1315943_+\|tail	phage tail assembly protein	B0ZSH0	Halomonas_phage	1.6e-29	39.3
WP_102666079.1\|1316173_1318294_+\|tail	phage tail tape measure protein	NA	NA	NA	NA
WP_014717171.1\|1318293_1318677_+\|tail	phage tail protein	A0A2H4JAC8	uncultured_Caudovirales_phage	1.3e-35	58.3
WP_014717172.1\|1318669_1318882_+\|tail	tail protein X	A0A2H4JGD9	uncultured_Caudovirales_phage	4.0e-18	65.7
WP_014717173.1\|1318891_1319893_+	hypothetical protein	A0A2H4JH05	uncultured_Caudovirales_phage	1.6e-96	52.7
WP_014717174.1\|1319915_1320473_+	glycoside hydrolase family 19 protein	B5TK83	Pseudomonas_phage	1.6e-74	72.1
WP_014717175.1\|1320625_1321126_+	CinA family protein	B5TK85	Pseudomonas_phage	4.1e-69	82.5
WP_014717176.1\|1321209_1322268_+	recombinase RecA	A0A0S2MVG1	Bacillus_phage	2.4e-111	62.4
WP_014717177.1\|1322276_1322744_+	recombination regulator RecX	NA	NA	NA	NA
WP_014717178.1\|1322805_1323918_-	TIGR00730 family Rossman fold protein	NA	NA	NA	NA
WP_014717179.1\|1324212_1324647_-	hypothetical protein	NA	NA	NA	NA
WP_014717180.1\|1324825_1325545_+	DTW domain-containing protein	NA	NA	NA	NA
WP_003189050.1\|1325796_1326447_+	response regulator transcription factor	NA	NA	NA	NA
WP_014717181.1\|1326522_1326885_+	diacylglycerol kinase	NA	NA	NA	NA
WP_003189054.1\|1326888_1327815_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003189055.1\|1327940_1328720_+	ferredoxin--NADP reductase	NA	NA	NA	NA
WP_014717182.1\|1328852_1329548_-\|tRNA	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO	NA	NA	NA	NA
WP_005785469.1\|1329552_1330014_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	2.6e-38	52.0
WP_014717183.1\|1330082_1330793_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_014717184.1\|1331015_1331486_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_169855583.1\|1331586_1332915_-	30S ribosomal protein S12 methylthiotransferase RimO	NA	NA	NA	NA
WP_014717185.1\|1333108_1333444_-	putative addiction module antidote protein	NA	NA	NA	NA
WP_014717186.1\|1333440_1333764_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A141GEX6	Brucella_phage	1.3e-12	37.2
WP_014717187.1\|1334178_1336080_+	potassium transporter Kup	M1IAJ4	Acanthocystis_turfacea_Chlorella_virus	2.9e-75	33.3
WP_014717188.1\|1336215_1337322_+	NADH:flavin oxidoreductase/NADH oxidase	NA	NA	NA	NA
WP_014717189.1\|1337425_1337962_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_014717190.1\|1338167_1338353_+	hypothetical protein	NA	NA	NA	NA
WP_014717191.1\|1338407_1340033_-	glucan biosynthesis protein D	NA	NA	NA	NA
WP_014717192.1\|1340337_1341045_+	tellurite resistance TerB family protein	NA	NA	NA	NA
WP_014717193.1\|1341255_1342878_+	methyl-accepting chemotaxis protein	NA	NA	NA	NA
WP_014717194.1\|1342877_1343390_+	purine-binding chemotaxis protein CheW	NA	NA	NA	NA
WP_014717195.1\|1343386_1344649_+	chemotaxis protein CheR	NA	NA	NA	NA
WP_014717196.1\|1344645_1345347_+	purine-binding chemotaxis protein CheW	NA	NA	NA	NA
WP_014717197.1\|1345343_1347617_+	hybrid sensor histidine kinase/response regulator	Q56AR1	Bacillus_thuringiensis_phage	7.4e-09	27.4
WP_003189079.1\|1347613_1348624_+	chemotaxis response regulator protein-glutamate methylesterase	Q6XM27	Feldmannia_irregularis_virus	9.9e-06	40.3
WP_014717198.1\|1348676_1349678_+	PleD family two-component system response regulator	A0A127AWB9	Bacillus_phage	1.6e-16	35.2
WP_096001736.1\|1349853_1350948_+	peptide chain release factor 2	A0A0S4KWG0	Pseudomonas_phage	2.0e-07	46.6
WP_003189082.1\|1351028_1352531_+\|tRNA	lysine--tRNA ligase	A0A2K9KZX5	Tupanvirus	5.5e-85	39.4
WP_014717200.1\|1352674_1353391_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_014717201.1\|1353487_1354765_+	flavohemoglobin expression-modulating QEGLA motif protein	NA	NA	NA	NA
WP_014717202.1\|1354857_1355763_+	alpha/beta hydrolase	A0A1C9C5K3	Heterosigma_akashiwo_virus	1.3e-09	30.0
WP_003172217.1\|1355759_1356086_+	hypothetical protein	NA	NA	NA	NA
WP_014717203.1\|1356237_1356594_+	hypothetical protein	NA	NA	NA	NA
WP_014717205.1\|1357085_1357871_-	OmpA family protein	NA	NA	NA	NA
WP_003189094.1\|1357927_1358353_-	DUF4398 domain-containing protein	NA	NA	NA	NA
WP_014717206.1\|1358636_1358981_-	hypothetical protein	NA	NA	NA	NA
WP_014717207.1\|1359180_1361826_+	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
WP_003189104.1\|1362106_1362754_+	adenylate kinase	A0A2K9L833	Tupanvirus	8.6e-11	32.5
WP_014717208.1\|1362844_1363531_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA

DBSCAN-SWA_2

1766343 : 1807839

Pseudomonas_virus(56.1%)

integrase,holin,portal,terminase,tRNA,transposase,head,plate,tail,capsid

attL 1765106:1765120|attR 1796212:1796226

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1765106:1765120	attL	NA	NA	NA	NA
WP_014717529.1\|1766343_1767354_-\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
WP_014717530.1\|1767457_1768609_+\|integrase	site-specific integrase	L7TP61	Pseudomonas_virus	5.8e-135	62.7
WP_014717531.1\|1768583_1768859_-	pyocin activator PrtN family protein	A0A2K8HN48	Pseudomonas_phage	2.4e-23	59.3
WP_014717532.1\|1768855_1769374_-	hypothetical protein	A0A1B0VMC7	Pseudomonas_phage	1.1e-13	40.7
WP_014717533.1\|1769385_1769637_-	hypothetical protein	NA	NA	NA	NA
WP_014717534.1\|1769633_1769951_-	hypothetical protein	NA	NA	NA	NA
WP_044483083.1\|1770224_1770827_-	hypothetical protein	NA	NA	NA	NA
WP_014717537.1\|1770829_1771093_-	hypothetical protein	NA	NA	NA	NA
WP_014717538.1\|1771151_1771463_-	hypothetical protein	NA	NA	NA	NA
WP_193385110.1\|1771525_1774324_-	toprim domain-containing protein	A0A2H4J936	uncultured_Caudovirales_phage	0.0e+00	61.7
WP_014717540.1\|1774335_1774581_-	hypothetical protein	Q9ZXI9	Pseudomonas_virus	2.3e-17	56.5
WP_014717541.1\|1774651_1775026_-	hypothetical protein	NA	NA	NA	NA
WP_014717542.1\|1775022_1775325_-	ogr/Delta-like zinc finger family protein	Q9ZXJ1	Pseudomonas_virus	2.3e-35	74.5
WP_014717543.1\|1775321_1775795_-	hypothetical protein	A0A2H4JG61	uncultured_Caudovirales_phage	7.8e-54	65.2
WP_044483570.1\|1775835_1776084_-	phage-associated protein, BcepMu gp16 family	NA	NA	NA	NA
WP_019818218.1\|1776185_1776593_+	helix-turn-helix domain-containing protein	A0A2H4J7C3	uncultured_Caudovirales_phage	6.8e-06	33.3
WP_144269774.1\|1776710_1777151_+	hypothetical protein	NA	NA	NA	NA
WP_014717546.1\|1777199_1778255_+	acetyltransferase	Q6SE88	Lactobacillus_prophage	1.2e-67	40.7
WP_044483084.1\|1778232_1778604_+	ASCH domain-containing protein	Q6SE87	Lactobacillus_prophage	5.2e-29	52.4
WP_014717547.1\|1778645_1779908_-	phage late control D family protein	Q9ZXJ8	Pseudomonas_virus	8.7e-193	80.5
WP_014717548.1\|1779904_1780345_-\|tail	phage tail protein	Q9ZXJ9	Pseudomonas_virus	1.4e-57	76.9
WP_014717549.1\|1780350_1783788_-\|tail	phage tail tape measure protein	E5FFG5	Burkholderia_phage	1.5e-114	32.5
WP_014717550.1\|1783777_1783897_-\|tail	GpE family phage tail protein	Q9ZXK1	Pseudomonas_virus	1.0e-10	79.5
WP_014717551.1\|1783905_1784241_-\|tail	phage tail assembly protein	Q9ZXK2	Pseudomonas_virus	2.7e-24	61.1
WP_014717552.1\|1784290_1784806_-\|tail	phage major tail tube protein	Q9ZXK3	Pseudomonas_virus	2.5e-74	78.4
WP_014717553.1\|1784863_1786033_-\|tail	phage tail sheath protein	Q9ZXK4	Pseudomonas_virus	2.6e-167	74.4
WP_080643472.1\|1786161_1786644_-	hypothetical protein	NA	NA	NA	NA
WP_014717555.1\|1786607_1788197_-\|tail	phage tail protein	A0A077K818	Ralstonia_phage	7.4e-72	41.5
WP_014717556.1\|1788193_1788895_-\|tail	phage tail protein I	A0A2H4JAU2	uncultured_Caudovirales_phage	8.0e-71	72.3
WP_014717557.1\|1788894_1789806_-\|plate	baseplate assembly protein	Q9ZXK8	Pseudomonas_virus	5.6e-125	75.1
WP_014717558.1\|1789802_1790147_-	GPW/gp25 family protein	Q9ZXK9	Pseudomonas_virus	1.3e-37	66.4
WP_014717559.1\|1790143_1790722_-\|plate	phage baseplate assembly protein V	Q9ZXL0	Pseudomonas_virus	7.1e-57	58.7
WP_044483086.1\|1790790_1791660_-	hypothetical protein	NA	NA	NA	NA
WP_014717561.1\|1791710_1792169_-	phage virion morphogenesis protein	Q9ZXL2	Pseudomonas_virus	2.1e-43	59.3
WP_014717562.1\|1792158_1792641_-\|tail	phage tail protein	Q9ZXL3	Pseudomonas_virus	4.8e-43	64.7
WP_014717564.1\|1792737_1793181_-	peptidase	Q9ZXL5	Pseudomonas_virus	8.7e-23	47.1
WP_044483088.1\|1793177_1793381_-	hypothetical protein	NA	NA	NA	NA
WP_014717566.1\|1793377_1794223_-	DUF3380 domain-containing protein	Q9ZXL6	Pseudomonas_virus	5.2e-101	69.4
WP_014717567.1\|1794219_1794498_-\|holin	phage holin family protein	Q9ZXL7	Pseudomonas_virus	3.8e-24	67.4
WP_014717568.1\|1794499_1794853_-	hypothetical protein	Q9ZXL8	Pseudomonas_virus	1.3e-29	58.1
WP_044483089.1\|1794880_1795093_-\|tail	tail protein X	Q9ZXL9	Pseudomonas_virus	8.4e-24	74.6
WP_014717569.1\|1795092_1795554_-\|head	head completion/stabilization protein	Q9ZXM1	Pseudomonas_virus	1.5e-49	63.4
WP_048889390.1\|1795550_1795847_-	hypothetical protein	E5FFG0	Burkholderia_phage	2.6e-07	52.5
WP_014717570.1\|1795945_1796647_-\|terminase	terminase endonuclease subunit	Q9ZXM2	Pseudomonas_virus	2.3e-86	71.4
1796212:1796226	attR	NA	NA	NA	NA
WP_014717571.1\|1796651_1797674_-\|capsid	phage major capsid protein, P2 family	Q9ZXM3	Pseudomonas_virus	1.9e-121	61.8
WP_014717572.1\|1797714_1798545_-\|capsid	GPO family capsid scaffolding protein	A0A2H4J928	uncultured_Caudovirales_phage	1.7e-72	54.7
WP_014717573.1\|1798700_1800458_+\|terminase	terminase ATPase subunit family protein	Q9ZXM5	Pseudomonas_virus	1.1e-286	80.9
WP_014717574.1\|1800457_1801507_+\|portal	phage portal protein	A0A2H4J922	uncultured_Caudovirales_phage	1.8e-143	76.1
WP_014717575.1\|1801665_1802460_+	DNA adenine methylase	C7BGE1	Burkholderia_phage	1.3e-101	66.5
WP_014717576.1\|1802456_1803137_-	SOS response-associated peptidase family protein	A0A2H4J991	uncultured_Caudovirales_phage	2.2e-126	92.4
WP_014717577.1\|1803220_1803430_+	hypothetical protein	A0A2H4J2T0	uncultured_Caudovirales_phage	1.6e-30	92.8
WP_014717578.1\|1803421_1803775_-	hypothetical protein	A0A2H4IZV2	uncultured_Caudovirales_phage	4.8e-40	74.8
WP_014717579.1\|1804836_1805127_-	hypothetical protein	NA	NA	NA	NA
WP_014717580.1\|1805811_1806249_+	acetyltransferase	NA	NA	NA	NA
WP_014717581.1\|1806300_1807839_-\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	8.0e-116	46.1

DBSCAN-SWA_3

2195276 : 2276157

104

Pseudomonas_phage(58.06%)

integrase,lysis,holin,terminase,tRNA,transposase,tail,capsid

attL 2195197:2195213|attR 2248170:2248186

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2195197:2195213	attL	NA	NA	NA	NA
WP_044483140.1\|2195276_2195489_-	AlpA family transcriptional regulator	A0A2H4J8C8	uncultured_Caudovirales_phage	1.7e-21	68.6
WP_014717866.1\|2195485_2195713_-	hypothetical protein	A0A2H4J1L2	uncultured_Caudovirales_phage	1.9e-21	80.6
WP_014717867.1\|2195820_2196171_-	hypothetical protein	NA	NA	NA	NA
WP_014717868.1\|2196163_2196685_-	hypothetical protein	A0A1B0VMC7	Pseudomonas_phage	5.5e-08	53.4
WP_193385111.1\|2196730_2197840_-	RNA-directed DNA polymerase	A0A0N7AE80	Bacillus_phage	5.4e-45	34.0
WP_014717870.1\|2198100_2198454_-	four helix bundle protein	NA	NA	NA	NA
WP_014717871.1\|2198512_2199109_-	hypothetical protein	A0A0A0YR68	Pseudomonas_phage	8.1e-24	40.6
WP_014717872.1\|2199229_2199706_-	hypothetical protein	NA	NA	NA	NA
WP_014717873.1\|2199798_2200584_-	methyltransferase	A0A219YCB7	Aeromonas_phage	1.7e-69	55.6
WP_014717874.1\|2200690_2200909_+	hypothetical protein	NA	NA	NA	NA
WP_014717875.1\|2200909_2201239_-	hypothetical protein	A0A2H4JAQ1	uncultured_Caudovirales_phage	1.3e-20	56.4
WP_014717876.1\|2201909_2202407_-	siphovirus Gp157 family protein	H2BDF7	Pseudomonas_virus	4.5e-52	64.2
WP_014717877.1\|2202403_2203135_-	hypothetical protein	A0A2H4J2D5	uncultured_Caudovirales_phage	8.3e-87	68.3
WP_014717878.1\|2203288_2203465_-	hypothetical protein	X5IGI5	Pseudomonas_phage	9.1e-08	58.5
WP_014717879.1\|2203461_2203665_-	hypothetical protein	A0A2H4J1S2	uncultured_Caudovirales_phage	1.2e-14	56.2
WP_014717880.1\|2203661_2203877_-	hypothetical protein	A0A2H4IZT6	uncultured_Caudovirales_phage	2.0e-28	85.9
WP_014717881.1\|2203873_2204302_-	hypothetical protein	A0A2H4J9E7	uncultured_Caudovirales_phage	1.2e-69	95.1
WP_014717882.1\|2204458_2204731_-	hypothetical protein	A0A2I7RQ39	Vibrio_phage	1.9e-12	50.0
WP_014717883.1\|2204815_2205193_-	hypothetical protein	NA	NA	NA	NA
WP_014717884.1\|2205193_2205445_-	DUF1654 domain-containing protein	NA	NA	NA	NA
WP_014717885.1\|2205612_2206212_+	SPOR domain-containing protein	A0A0M4QWT0	Salmonella_phage	2.4e-07	42.6
WP_014717886.1\|2206272_2207109_-	DUF3037 domain-containing protein	NA	NA	NA	NA
WP_014717887.1\|2207105_2207849_-	hypothetical protein	NA	NA	NA	NA
WP_080643512.1\|2207982_2208591_-	helix-turn-helix transcriptional regulator	B5TK58	Pseudomonas_phage	2.7e-75	84.9
WP_044483145.1\|2208852_2209065_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014717889.1\|2209133_2209601_+	hypothetical protein	A0A1B0VP44	Pseudomonas_phage	4.0e-58	76.3
WP_044483147.1\|2209662_2210523_+	Bro-N domain-containing protein	A0A2H4J111	uncultured_Caudovirales_phage	8.3e-54	69.4
WP_014717891.1\|2210524_2211502_+	hypothetical protein	A0A1B0VME0	Pseudomonas_phage	1.6e-114	73.5
WP_044483149.1\|2211488_2212286_+	hypothetical protein	A0A1B0VMD9	Pseudomonas_phage	3.4e-94	68.1
WP_014717893.1\|2212282_2212798_+	hypothetical protein	A0A2K8I9A9	Pseudomonas_phage	2.3e-35	45.0
WP_014717894.1\|2212794_2213424_+	recombination protein NinG	A0A2H4JA27	uncultured_Caudovirales_phage	5.3e-74	69.8
WP_158470835.1\|2213444_2213990_+	HNH endonuclease	A0A2H4JH74	uncultured_Caudovirales_phage	4.6e-74	72.1
WP_014717896.1\|2214057_2214603_+	hypothetical protein	A0A0H5AWB8	Pseudomonas_phage	2.1e-66	69.1
WP_080643478.1\|2215113_2215299_+	Com family DNA-binding transcriptional regulator	B5TK59	Pseudomonas_phage	2.9e-12	89.5
WP_014717898.1\|2215308_2215815_+	hypothetical protein	NA	NA	NA	NA
WP_014717899.1\|2216030_2216360_+\|holin	phage holin, lambda family	A0A2D1GNJ3	Pseudomonas_phage	5.3e-33	63.6
WP_044483151.1\|2216417_2216714_+	hypothetical protein	V5K3F8	Pseudomonas_phage	3.9e-11	36.7
WP_014717902.1\|2217088_2217280_+	hypothetical protein	NA	NA	NA	NA
WP_014717903.1\|2217276_2217531_+	hypothetical protein	NA	NA	NA	NA
WP_044483153.1\|2217562_2217769_-	hypothetical protein	NA	NA	NA	NA
WP_014717904.1\|2217841_2218465_+	hypothetical protein	A0A1B0VRJ1	Pseudomonas_phage	4.9e-104	85.5
WP_014717905.1\|2218496_2218958_+	DUF2280 domain-containing protein	A0A1B0VMH2	Pseudomonas_phage	6.7e-50	78.9
WP_014717906.1\|2218944_2220246_+\|terminase	terminase	A0A1B1P9C9	Acinetobacter_phage	5.7e-147	59.2
WP_014717907.1\|2220242_2221661_+	DUF4055 domain-containing protein	A0A1B0VMH0	Pseudomonas_phage	3.1e-263	92.8
WP_014717908.1\|2221635_2222724_+\|capsid	minor capsid protein	A0A1B0VMF3	Pseudomonas_phage	3.0e-189	95.6
WP_048889392.1\|2222746_2223355_+	hypothetical protein	NA	NA	NA	NA
WP_014717910.1\|2223446_2224175_+	hypothetical protein	A0A1B0VMG1	Pseudomonas_phage	3.1e-126	98.8
WP_014717911.1\|2224187_2225150_+	Ig domain-containing protein	A0A1B0VMF8	Pseudomonas_phage	5.1e-177	98.7
WP_144269778.1\|2225175_2225787_+	hypothetical protein	A0A1B0VMF7	Pseudomonas_phage	1.9e-84	82.3
WP_014717913.1\|2225846_2226350_+	hypothetical protein	A0A1B0VND3	Pseudomonas_phage	3.6e-81	91.0
WP_034136281.1\|2226353_2226659_-	hypothetical protein	NA	NA	NA	NA
WP_034136295.1\|2226681_2227050_+	hypothetical protein	A0A1B0VRJ4	Pseudomonas_phage	5.0e-56	88.3
WP_014717915.1\|2227046_2227643_+	hypothetical protein	A0A1B0VMI1	Pseudomonas_phage	1.4e-52	52.8
WP_014717916.1\|2227639_2228059_+	DUF4128 domain-containing protein	A0A1B0VMI0	Pseudomonas_phage	3.1e-62	87.6
WP_014717917.1\|2228128_2228800_+\|tail	phage tail protein	A0A0H5BBY3	Pseudomonas_phage	3.6e-44	41.9
WP_014717918.1\|2228802_2229183_+\|tail	phage tail assembly chaperone	A0A2H4IYQ5	uncultured_Caudovirales_phage	2.5e-26	49.6
WP_093114111.1\|2229260_2229503_+	DUF1799 domain-containing protein	A0A2H4J4F7	uncultured_Caudovirales_phage	4.4e-21	57.3
WP_014717920.1\|2229530_2232572_+\|tail	phage tail tape measure protein	A0A1B0VMG8	Pseudomonas_phage	1.1e-201	45.2
WP_014717921.1\|2232571_2232910_+\|tail	phage tail protein	A0A1B0VMG7	Pseudomonas_phage	3.9e-55	84.8
WP_014717922.1\|2232919_2233672_+\|tail	phage minor tail protein L	A0A1B0VNE0	Pseudomonas_phage	5.6e-139	92.0
WP_014717923.1\|2233674_2234439_+	C40 family peptidase	A0A1B0VP68	Pseudomonas_phage	9.1e-137	88.0
WP_014717924.1\|2234580_2234751_+	hypothetical protein	NA	NA	NA	NA
WP_014717925.1\|2234747_2235206_+	type II toxin-antitoxin system YafO family toxin	NA	NA	NA	NA
WP_014717926.1\|2235294_2235639_+	hypothetical protein	A0A1B0VMC6	Pseudomonas_phage	1.3e-18	53.3
WP_014717927.1\|2235689_2236271_+\|tail	tail assembly protein	A0A1B0VME1	Pseudomonas_phage	9.8e-83	80.8
WP_014717928.1\|2236330_2240326_+	DUF1983 domain-containing protein	A0A1B0VMH5	Pseudomonas_phage	0.0e+00	74.1
WP_014717929.1\|2240327_2240633_+	hypothetical protein	NA	NA	NA	NA
WP_080643479.1\|2240605_2241535_+	hypothetical protein	NA	NA	NA	NA
WP_177336913.1\|2241689_2242388_+\|tail	phage tail protein	A0A0S2SY45	Pseudomonas_phage	9.9e-21	44.3
WP_014717932.1\|2242384_2242675_+	hypothetical protein	A0A0A0YUD8	Pseudomonas_phage	3.3e-15	45.0
WP_014717933.1\|2242671_2242926_+	hypothetical protein	A0A1W6JT87	Pseudomonas_phage	9.4e-14	51.4
WP_014717934.1\|2242983_2243409_+	cell wall hydrolase	A0A1B0VMI2	Pseudomonas_phage	1.2e-74	92.2
WP_014717935.1\|2243408_2243942_+\|lysis	lysis protein	A0A2H4IZW4	uncultured_Caudovirales_phage	1.2e-53	68.0
WP_014717936.1\|2243942_2244851_-	hypothetical protein	NA	NA	NA	NA
WP_014717937.1\|2244984_2245668_-	SOS response-associated peptidase family protein	A0A2H4J991	uncultured_Caudovirales_phage	1.3e-129	95.5
WP_044483161.1\|2245751_2245961_+	hypothetical protein	A0A2H4J2T0	uncultured_Caudovirales_phage	4.1e-31	95.7
WP_014717939.1\|2245952_2246306_-	hypothetical protein	A0A2H4IZV2	uncultured_Caudovirales_phage	1.9e-41	77.3
WP_014717940.1\|2246458_2246815_+	hypothetical protein	NA	NA	NA	NA
WP_014717941.1\|2246816_2248004_-\|integrase	tyrosine-type recombinase/integrase	A0A2D1GNR7	Pseudomonas_phage	8.1e-217	95.6
WP_014717942.1\|2248283_2249363_-	hypothetical protein	NA	NA	NA	NA
2248170:2248186	attR	NA	NA	NA	NA
WP_014717943.1\|2249521_2249824_+	PepSY domain-containing protein	NA	NA	NA	NA
WP_003190266.1\|2249823_2250135_+	PepSY domain-containing protein	NA	NA	NA	NA
WP_003190268.1\|2250134_2250803_+	response regulator transcription factor	NA	NA	NA	NA
WP_014717944.1\|2250799_2252113_+	sensor histidine kinase	NA	NA	NA	NA
WP_014717945.1\|2252241_2254389_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.1e-22	54.1
WP_161793214.1\|2254618_2255938_+	TRAP transporter large permease subunit	NA	NA	NA	NA
WP_014717946.1\|2256117_2257797_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	4.0e-28	43.5
WP_014717947.1\|2257819_2259133_-\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	4.7e-149	70.9
WP_014717948.1\|2259304_2260372_+	AI-2E family transporter	NA	NA	NA	NA
WP_003190283.1\|2260375_2260558_-	hypothetical protein	NA	NA	NA	NA
WP_014717949.1\|2260649_2260844_-	hypothetical protein	NA	NA	NA	NA
WP_019818659.1\|2261077_2261452_-	hypothetical protein	NA	NA	NA	NA
WP_014717950.1\|2261608_2262427_+	shikimate 5-dehydrogenase	NA	NA	NA	NA
WP_074059269.1\|2262766_2264068_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_014717951.1\|2264446_2265097_-	DUF480 domain-containing protein	NA	NA	NA	NA
WP_014717952.1\|2265214_2265724_+	DUF1993 domain-containing protein	NA	NA	NA	NA
WP_044483165.1\|2266008_2269164_+	hypothetical protein	NA	NA	NA	NA
WP_014717954.1\|2269235_2270456_-	serine/threonine transporter SstT	NA	NA	NA	NA
WP_014717955.1\|2270697_2271852_+	MFS transporter	NA	NA	NA	NA
WP_014717956.1\|2271856_2272759_-	transcriptional activator NhaR	NA	NA	NA	NA
WP_014717957.1\|2272893_2273145_+	hypothetical protein	NA	NA	NA	NA
WP_014717958.1\|2273176_2273926_+	TerC family protein	A0A0R6PEZ3	Moraxella_phage	2.1e-40	41.6
WP_014717959.1\|2274019_2275054_+	selenide, water dikinase SelD	NA	NA	NA	NA
WP_014717960.1\|2275053_2276157_+\|tRNA	tRNA 2-selenouridine(34) synthase MnmH	NA	NA	NA	NA

DBSCAN-SWA_4

2578148 : 2633837

Planktothrix_phage(50.0%)

protease,transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080643515.1\|2578148_2579450_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_014718183.1\|2579788_2581165_-	VOC family protein	NA	NA	NA	NA
WP_014718184.1\|2581363_2584000_+	glucosidase	NA	NA	NA	NA
WP_014718185.1\|2584191_2584506_-	SCP2 sterol-binding domain-containing protein	NA	NA	NA	NA
WP_014718186.1\|2584562_2585273_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_014718187.1\|2585467_2586493_+\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	2.5e-20	32.1
WP_014718188.1\|2586641_2587286_-	dihydroxyacetone kinase subunit L	NA	NA	NA	NA
WP_014718189.1\|2587289_2588291_-	dihydroxyacetone kinase subunit DhaK	NA	NA	NA	NA
WP_019817618.1\|2588447_2589563_-	erythritol/L-threitol dehydrogenase	NA	NA	NA	NA
WP_014718191.1\|2589590_2590346_-	D-threitol dehydrogenase	NA	NA	NA	NA
WP_014718192.1\|2590467_2591475_-	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_014718193.1\|2591509_2592487_-	ABC transporter permease	NA	NA	NA	NA
WP_014718194.1\|2592483_2593971_-	sugar ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_014718195.1\|2594233_2594695_+	ribose 5-phosphate isomerase B	NA	NA	NA	NA
WP_003191835.1\|2594758_2595739_+	sugar-binding transcriptional regulator	NA	NA	NA	NA
WP_014718196.1\|2596173_2597742_+	TerC family protein	A0A0R6PEZ3	Moraxella_phage	6.9e-38	42.9
WP_014718197.1\|2598378_2599227_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_014718198.1\|2599279_2599942_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_014718199.1\|2599953_2600616_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_014718200.1\|2600612_2601395_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-30	38.0
WP_003191822.1\|2601409_2601799_+	RidA family protein	NA	NA	NA	NA
WP_014718201.1\|2601933_2602698_+	IclR family transcriptional regulator	NA	NA	NA	NA
WP_014718202.1\|2602707_2603916_+	amino acid deaminase	NA	NA	NA	NA
WP_014718203.1\|2604044_2604950_+	sugar kinase	NA	NA	NA	NA
WP_003174397.1\|2605109_2605385_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_014718204.1\|2605428_2607966_-	PAS domain-containing protein	NA	NA	NA	NA
WP_014718205.1\|2608104_2610060_-	acetoacetate--CoA ligase	NA	NA	NA	NA
WP_014718206.1\|2610187_2610961_-	3-hydroxybutyrate dehydrogenase	NA	NA	NA	NA
WP_014718207.1\|2610968_2612360_-	GntP family permease	NA	NA	NA	NA
WP_014718208.1\|2612653_2614045_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_014718209.1\|2614191_2615763_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.2e-19	34.4
WP_014718210.1\|2615773_2616796_-	ABC transporter permease	NA	NA	NA	NA
WP_005788805.1\|2616795_2617854_-	microcin C ABC transporter permease YejB	NA	NA	NA	NA
WP_014718211.1\|2617853_2619713_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014718212.1\|2619843_2620125_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_014718213.1\|2620233_2620728_-	DUF1543 domain-containing protein	NA	NA	NA	NA
WP_014718214.1\|2621286_2621802_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_193385112.1\|2622270_2623815_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_014718216.1\|2623839_2624337_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_014718217.1\|2624364_2625843_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_014718218.1\|2625857_2626259_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_014718219.1\|2626248_2628036_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_014718220.1\|2627999_2629007_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_014718221.1\|2629111_2630641_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_014718222.1\|2630676_2630808_+	hypothetical protein	NA	NA	NA	NA
WP_014718223.1\|2630819_2632016_+	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_014718224.1\|2632021_2632507_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_014718225.1\|2632508_2633837_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA

DBSCAN-SWA_5

2882551 : 2959321

Bacillus_phage(50.0%)

protease,integrase,transposase

attL 2898363:2898390|attR 2964504:2964531

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014718404.1\|2882551_2883985_+\|protease	serralysin family metalloprotease	NA	NA	NA	NA
WP_014718405.1\|2884033_2884402_+\|protease	AprI/Inh family metalloprotease inhibitor	NA	NA	NA	NA
WP_014718406.1\|2884502_2886254_+	type I secretion system permease/ATPase	W8CYL7	Bacillus_phage	8.8e-26	30.6
WP_014718407.1\|2886250_2887564_+	HlyD family type I secretion periplasmic adaptor subunit	NA	NA	NA	NA
WP_003191155.1\|2887566_2888907_+	TolC family outer membrane protein	NA	NA	NA	NA
WP_014718408.1\|2889032_2891990_+\|protease	autotransporter serine protease	NA	NA	NA	NA
WP_014718409.1\|2892195_2895303_+\|protease	autotransporter serine protease	NA	NA	NA	NA
WP_074059269.1\|2895417_2896719_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_014718410.1\|2896862_2898287_+	lipase	NA	NA	NA	NA
2898363:2898390	attL	NA	NA	NA	NA
WP_003191162.1\|2898408_2898633_-	YgdI/YgdR family lipoprotein	NA	NA	NA	NA
WP_014718411.1\|2898822_2900469_+	VRR-NUC domain-containing protein	NA	NA	NA	NA
WP_014718412.1\|2900465_2902727_+	ATP-dependent DNA helicase	NA	NA	NA	NA
WP_014718413.1\|2902758_2903709_-	alpha-E domain-containing protein	NA	NA	NA	NA
WP_014718414.1\|2903711_2905121_-	circularly permuted type 2 ATP-grasp protein	NA	NA	NA	NA
WP_014718415.1\|2906774_2907320_+	hypothetical protein	NA	NA	NA	NA
WP_014718416.1\|2907405_2907618_+	hypothetical protein	NA	NA	NA	NA
WP_014718418.1\|2907754_2908102_-	helix-turn-helix transcriptional regulator	A4JWR8	Burkholderia_virus	1.5e-09	43.3
WP_014718419.1\|2908157_2909504_-	cation:proton antiporter	NA	NA	NA	NA
WP_014718420.1\|2909722_2910166_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_014718421.1\|2910274_2911183_+	DMT family transporter	NA	NA	NA	NA
WP_014718422.1\|2911259_2913239_-	U32 family peptidase	Q6DW11	Phage_TP	4.6e-23	28.9
WP_014718423.1\|2913501_2913882_-	RidA family protein	NA	NA	NA	NA
WP_014718424.1\|2913953_2915222_-	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_014718425.1\|2915329_2915806_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014718426.1\|2915810_2916680_-	oxaloacetate decarboxylase	NA	NA	NA	NA
WP_014718427.1\|2916807_2916939_+	ATP-binding protein	NA	NA	NA	NA
WP_014718428.1\|2917115_2918072_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014718429.1\|2918094_2919426_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_014718430.1\|2919522_2920362_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014718431.1\|2920398_2921781_+	aspartate aminotransferase family protein	NA	NA	NA	NA
WP_014718432.1\|2921926_2923306_+	APC family permease	NA	NA	NA	NA
WP_014718433.1\|2923528_2925019_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_014718434.1\|2925150_2926083_+	cupin	NA	NA	NA	NA
WP_014718435.1\|2926084_2926990_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_014718436.1\|2927107_2927368_-	metallothionein	NA	NA	NA	NA
WP_003191203.1\|2927424_2927652_-	hypothetical protein	NA	NA	NA	NA
WP_014718437.1\|2927869_2929597_+	formyl transferase	NA	NA	NA	NA
WP_014718438.1\|2929739_2930348_+	thymidylate kinase	NA	NA	NA	NA
WP_014718439.1\|2930667_2930916_+	CsbD family protein	NA	NA	NA	NA
WP_014718440.1\|2931406_2932774_+	epoxide hydrolase	NA	NA	NA	NA
WP_014718441.1\|2932836_2933910_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_014718442.1\|2933934_2934444_+	cytochrome P460 family protein	NA	NA	NA	NA
WP_014718443.1\|2934469_2935246_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_014718445.1\|2935686_2936898_-	cytochrome c biogenesis protein DipZ	NA	NA	NA	NA
WP_014718446.1\|2936928_2937189_-	DUF2790 domain-containing protein	NA	NA	NA	NA
WP_014718447.1\|2937493_2938234_+	response regulator	NA	NA	NA	NA
WP_014718448.1\|2938230_2939538_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	3.5e-11	22.5
WP_193385108.1\|2940498_2941740_+	AAA family ATPase	NA	NA	NA	NA
WP_193385109.1\|2941751_2942768_+	hypothetical protein	NA	NA	NA	NA
WP_014718449.1\|2942887_2944900_+	AAA family ATPase	NA	NA	NA	NA
WP_144269783.1\|2945323_2946370_-	hypothetical protein	NA	NA	NA	NA
WP_144269797.1\|2947720_2951587_-	DUF4365 domain-containing protein	NA	NA	NA	NA
WP_014718453.1\|2951963_2954840_+	AAA family ATPase	NA	NA	NA	NA
WP_044483236.1\|2955696_2957814_-	hypothetical protein	NA	NA	NA	NA
WP_014718456.1\|2957800_2959321_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
2964504:2964531	attR	NA	NA	NA	NA

DBSCAN-SWA_6

3553397 : 3559616

uncultured_Caudovirales_phage(83.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003192069.1\|3553397_3553790_+	sulfurtransferase complex subunit TusD	A0A2H4JA39	uncultured_Caudovirales_phage	3.3e-58	86.2
WP_014718891.1\|3553791_3554142_+	sulfurtransferase complex subunit TusC	A0A2H4J8C0	uncultured_Caudovirales_phage	2.6e-38	67.8
WP_014718892.1\|3554141_3554420_+	sulfurtransferase complex subunit TusB	A0A2H4JG28	uncultured_Caudovirales_phage	2.4e-26	58.6
WP_014718893.1\|3554416_3554752_+	TusE/DsrC/DsvC family sulfur relay protein	A0A2H4J8B6	uncultured_Caudovirales_phage	8.0e-45	78.4
WP_014718894.1\|3554748_3555750_+	glycosyl transferase family protein	A0A2H4JBY5	uncultured_Caudovirales_phage	3.5e-168	86.3
WP_014718895.1\|3555838_3556834_+	glutathione S-transferase family protein	NA	NA	NA	NA
WP_014718896.1\|3556940_3558335_-	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_014718897.1\|3558335_3559616_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	5.3e-97	53.5

DBSCAN-SWA_7

3628565 : 3697336

Escherichia_phage(16.67%)

protease,tRNA,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014718938.1\|3628565_3629948_-\|tRNA	cysteine--tRNA ligase	A0A2K9L6B7	Tupanvirus	5.7e-44	31.0
WP_014718939.1\|3629963_3631664_-\|tRNA	glutamine--tRNA ligase/YqeY domain fusion protein	A0A222YZ70	Escherichia_phage	3.4e-208	62.6
WP_014718940.1\|3631901_3632408_+	peptidyl-prolyl cis-trans isomerase	A0A076FI46	Aureococcus_anophage	4.3e-10	32.7
WP_014718941.1\|3632404_3633154_+	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_014718942.1\|3633303_3634833_-	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_014718943.1\|3634832_3636032_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_014718944.1\|3636047_3637499_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_014718945.1\|3637495_3637969_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_080643491.1\|3638206_3641893_-	translocation/assembly module TamB	NA	NA	NA	NA
WP_014718947.1\|3641892_3643620_-	outer membrane protein assembly factor	NA	NA	NA	NA
WP_014718948.1\|3643684_3644335_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_014718949.1\|3644501_3645314_+	exodeoxyribonuclease III	NA	NA	NA	NA
WP_014718950.1\|3645511_3646843_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_014718951.1\|3646964_3648194_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_014718952.1\|3648345_3649275_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003192195.1\|3649328_3649721_+	MerR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_014718953.1\|3649737_3650640_+	hydroxymethylglutaryl-CoA lyase	A0A1V0SKU2	Klosneuvirus	3.1e-43	38.6
WP_014718955.1\|3653062_3654226_+	isovaleryl-CoA dehydrogenase	NA	NA	NA	NA
WP_014718956.1\|3654238_3655846_+	methylcrotonoyl-CoA carboxylase	A0A1B2ITV7	Pike_perch_iridovirus	3.3e-19	56.5
WP_014718957.1\|3655979_3656786_+	gamma-carboxygeranoyl-CoA hydratase	NA	NA	NA	NA
WP_014718958.1\|3656782_3658708_+	acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha	NA	NA	NA	NA
WP_014718959.1\|3658704_3659340_-	helix-turn-helix domain-containing protein	Q37946	Enterobacteria_phage	1.6e-38	41.7
WP_014718960.1\|3659527_3659821_+	DUF3077 domain-containing protein	NA	NA	NA	NA
WP_014718961.1\|3660285_3661437_+	carboxypeptidase family protein	NA	NA	NA	NA
WP_003192209.1\|3661488_3662028_-	cytochrome b	NA	NA	NA	NA
WP_014718962.1\|3662024_3663107_-	catalase family peroxidase	NA	NA	NA	NA
WP_014718963.1\|3663274_3663781_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_014718964.1\|3663777_3664515_+	anti-sigma factor	NA	NA	NA	NA
WP_014718965.1\|3664511_3665432_-\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_014718966.1\|3665509_3667858_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_014718967.1\|3667930_3668719_-	molecular chaperone	NA	NA	NA	NA
WP_014718968.1\|3668745_3669234_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_003192220.1\|3669236_3669779_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_014718969.1\|3669797_3670343_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_093114405.1\|3670336_3670828_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_014718971.1\|3671018_3672113_+	cell division protein ZapE	NA	NA	NA	NA
WP_014718972.1\|3672150_3673449_+	protein kinase	A0A0M4JT11	Mollivirus	5.7e-06	25.9
WP_003192227.1\|3673571_3674276_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_014718973.1\|3674385_3675711_-	MFS transporter	NA	NA	NA	NA
WP_014718974.1\|3675969_3676860_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_014718975.1\|3676835_3677690_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_014718976.1\|3677801_3678911_+	2-aminoethylphosphonate--pyruvate transaminase	NA	NA	NA	NA
WP_014718977.1\|3678939_3679767_+	phosphonoacetaldehyde hydrolase	NA	NA	NA	NA
WP_014718978.1\|3679881_3680436_+	cytochrome b	A0A0U2QLA7	Escherichia_phage	9.6e-19	43.3
WP_014718979.1\|3680587_3681478_-	pyridoxal-phosphate dependent enzyme	NA	NA	NA	NA
WP_014718980.1\|3681535_3683575_-	NADPH-dependent 2,4-dienoyl-CoA reductase	NA	NA	NA	NA
WP_014718981.1\|3683786_3684917_+	carbon-nitrogen hydrolase family protein	NA	NA	NA	NA
WP_014718982.1\|3684921_3685956_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_014718983.1\|3686322_3687114_-	DUF2242 domain-containing protein	NA	NA	NA	NA
WP_014718984.1\|3687202_3688102_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_014718985.1\|3688218_3689400_+	MFS transporter	NA	NA	NA	NA
WP_014718986.1\|3689518_3690862_+	Na+/H+ antiporter NhaA	A0A2H4J5W3	uncultured_Caudovirales_phage	8.4e-61	39.3
WP_014718987.1\|3690943_3692818_-	SurA N-terminal domain-containing protein	NA	NA	NA	NA
WP_003174819.1\|3693046_3693319_-	HU family DNA-binding protein	A3E2K9	Sodalis_phage	1.8e-18	59.6
WP_003192252.1\|3693468_3695865_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	1.2e-219	51.6
WP_003192254.1\|3696052_3697336_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.6e-138	59.7

DBSCAN-SWA_8

5422167 : 5472252

Tupanvirus(16.67%)

protease,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014720226.1\|5422167_5422668_-\|protease	ATP-dependent zinc protease	NA	NA	NA	NA
WP_014720227.1\|5422839_5423736_+	acyltransferase	NA	NA	NA	NA
WP_130175537.1\|5423769_5424048_-	hypothetical protein	NA	NA	NA	NA
WP_014720228.1\|5424221_5424794_-	DUF2780 domain-containing protein	NA	NA	NA	NA
WP_014720229.1\|5424930_5425389_+	anti-sigma factor	NA	NA	NA	NA
WP_014720230.1\|5425584_5426784_-	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	1.1e-11	29.7
WP_014720231.1\|5426967_5427825_-	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_014720232.1\|5427950_5428583_-	sarcosine oxidase subunit gamma family protein	NA	NA	NA	NA
WP_014720233.1\|5428719_5431737_-	sarcosine oxidase subunit alpha	NA	NA	NA	NA
WP_003194855.1\|5431733_5432036_-	sarcosine oxidase subunit delta	NA	NA	NA	NA
WP_003176546.1\|5432051_5433302_-	sarcosine oxidase subunit beta	NA	NA	NA	NA
WP_003194857.1\|5433324_5434578_-	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	1.3e-100	52.7
WP_014720234.1\|5434814_5435543_-	conjugal transfer protein TraX	NA	NA	NA	NA
WP_014720235.1\|5435633_5436674_+	low specificity L-threonine aldolase	NA	NA	NA	NA
WP_014720236.1\|5436867_5437068_+	hypothetical protein	NA	NA	NA	NA
WP_014720237.1\|5437652_5438753_-	glycine-betaine demethylase subunit GbcB	NA	NA	NA	NA
WP_014720238.1\|5439035_5440331_+	glycine-betaine demethylase subunit GbcA	NA	NA	NA	NA
WP_014720240.1\|5441449_5442670_+	lytic polysaccharide monooxygenase	Q9PYT6	Xestia_c-nigrum_granulosis_virus	8.3e-23	32.9
WP_165901703.1\|5442743_5443520_-	electron transfer flavoprotein subunit beta	NA	NA	NA	NA
WP_014720242.1\|5443524_5444745_-	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_014720243.1\|5444744_5446688_-	dimethylglycine demethylation protein DgcB	NA	NA	NA	NA
WP_014720244.1\|5446825_5448886_-	dimethylglycine demethylation protein DgcA	NA	NA	NA	NA
WP_005792152.1\|5448901_5449432_-	4-vinyl reductase	NA	NA	NA	NA
WP_014720245.1\|5449510_5450488_-	membrane dipeptidase	NA	NA	NA	NA
WP_014720247.1\|5450706_5451108_+	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_014720248.1\|5451151_5452114_-	tyrosinase family protein	NA	NA	NA	NA
WP_014720249.1\|5452304_5452721_+	DUF3010 family protein	NA	NA	NA	NA
WP_014720250.1\|5452752_5453931_-	ATP-binding protein	NA	NA	NA	NA
WP_014720251.1\|5453999_5454944_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_014720252.1\|5455139_5456084_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014720253.1\|5456172_5457060_+	3-keto-5-aminohexanoate cleavage protein	NA	NA	NA	NA
WP_014720254.1\|5457135_5458101_+	L-carnitine dehydrogenase	NA	NA	NA	NA
WP_014720255.1\|5458203_5458698_+	thioesterase family protein	NA	NA	NA	NA
WP_014720256.1\|5458921_5459185_+	hypothetical protein	NA	NA	NA	NA
WP_003194907.1\|5459272_5460376_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_014720257.1\|5460905_5462282_-	L-serine ammonia-lyase	NA	NA	NA	NA
WP_014720258.1\|5462698_5463646_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003194913.1\|5463715_5464561_+\|holin	choline ABC transporter permease subunit	NA	NA	NA	NA
WP_014720259.1\|5464557_5465736_+\|holin	choline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.5e-26	36.8
WP_014720260.1\|5465893_5467885_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	1.5e-18	26.4
WP_003194919.1\|5468217_5468811_+	transcriptional regulator BetI	NA	NA	NA	NA
WP_014720261.1\|5468921_5470394_+	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_014720262.1\|5470548_5472252_+\|holin	choline dehydrogenase	A0A1V0SI18	Klosneuvirus	2.9e-50	30.3

DBSCAN-SWA_9

5534877 : 5545368

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014720315.1\|5534877_5535117_-	hypothetical protein	B5TK57	Pseudomonas_phage	5.9e-10	56.1
WP_014720316.1\|5535551_5535839_+	HigA family addiction module antidote protein	A0A0M3LPV0	Mannheimia_phage	1.6e-17	49.4
WP_003195048.1\|5535975_5536431_-	chemotaxis protein CheW	NA	NA	NA	NA
WP_014720317.1\|5536423_5542243_-	Hpt domain-containing protein	W8CYM9	Bacillus_phage	3.7e-12	35.9
WP_014720318.1\|5542418_5544470_-	type IV pili methyl-accepting chemotaxis transducer N-terminal domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	9.3e-19	40.3
WP_014720319.1\|5544466_5544991_-	chemotaxis protein CheW	Q56AR1	Bacillus_thuringiensis_phage	2.0e-05	33.8
WP_014720320.1\|5545002_5545368_-	twitching motility response regulator PilH	W8CYM9	Bacillus_phage	1.1e-12	33.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_017911

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection