CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NC_018023	Mycolicibacterium chubuense NBB4 plasmid pMYCCH.02, complete sequence	0 crisprs	NA	0	0	1
NC_018027	Mycolicibacterium chubuense NBB4, complete sequence	4 crisprs	csa3,WYL,cas3,casR,cas4,DEDDh,DinG	3	1	2
NC_018022	Mycolicibacterium chubuense NBB4 plasmid pMYCCH.01, complete sequence	0 crisprs	csa3	0	0	5

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2452 : 79604

Mycobacterium_phage(20.0%)

transposase,integrase

attL 1745:1760|attR 88988:89003

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1745:1760	attL	NA	NA	NA	NA
WP_014805796.1\|2452_3508_-\|integrase	tyrosine-type recombinase/integrase	S5M9V8	Brevibacillus_phage	1.2e-09	23.7
WP_085980924.1\|3979_5139_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	4.4e-34	34.1
WP_014805800.1\|6405_6672_+	hypothetical protein	NA	NA	NA	NA
WP_014805801.1\|7233_8649_+	aldehyde dehydrogenase family protein	A0A1X9I5D4	Streptococcus_phage	7.4e-07	28.3
WP_085980925.1\|8764_10156_+	triacylglycerol lipase	NA	NA	NA	NA
WP_041783940.1\|10583_11411_+	ABC transporter permease	NA	NA	NA	NA
WP_014805804.1\|11407_12133_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.2e-23	35.2
WP_014805805.1\|12152_13127_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014805806.1\|13263_15660_+	molybdopterin-dependent oxidoreductase	A0A077SK27	Escherichia_phage	6.1e-62	29.0
WP_014805807.1\|15816_17364_-	argininosuccinate lyase	NA	NA	NA	NA
WP_081495207.1\|17360_18350_-	pyridoxal-phosphate dependent enzyme	NA	NA	NA	NA
WP_014805809.1\|18364_19717_-	adenylosuccinate lyase family protein	A0A1B1ISB0	uncultured_Mediterranean_phage	3.2e-07	24.6
WP_014805810.1\|19697_20624_-	hypothetical protein	NA	NA	NA	NA
WP_014805811.1\|20620_21394_-	phosphohydrolase	NA	NA	NA	NA
WP_014805812.1\|21561_22956_+	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	3.6e-06	24.3
WP_014805813.1\|22952_23726_+	glucose 1-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	3.9e-18	31.8
WP_041783955.1\|23741_24005_+	hypothetical protein	NA	NA	NA	NA
WP_014805816.1\|25339_25936_+	hypothetical protein	NA	NA	NA	NA
WP_014805817.1\|25946_27689_+	CdaR family transcriptional regulator	NA	NA	NA	NA
WP_014805818.1\|27811_28720_+	CoA transferase subunit A	NA	NA	NA	NA
WP_014805819.1\|28716_29559_+	glutaconate CoA-transferase	NA	NA	NA	NA
WP_014805820.1\|29546_31538_+	acetate--CoA ligase family protein	NA	NA	NA	NA
WP_014805821.1\|31650_32760_+	cobalamin-independent methionine synthase II family protein	NA	NA	NA	NA
WP_014805822.1\|33078_34131_+	methane monooxygenase	NA	NA	NA	NA
WP_014805823.1\|34154_34484_+	monooxygenase	NA	NA	NA	NA
WP_014805824.1\|34530_36033_+	methane monooxygenase	NA	NA	NA	NA
WP_014805825.1\|36151_37183_+	2Fe-2S iron-sulfur cluster binding domain-containing protein	NA	NA	NA	NA
WP_014805826.1\|37231_37882_+	fumarylacetoacetate hydrolase	NA	NA	NA	NA
WP_014805827.1\|38221_38560_+	hypothetical protein	NA	NA	NA	NA
WP_014805828.1\|38718_42102_+	pyruvate carboxylase	NA	NA	NA	NA
WP_014805829.1\|42764_44084_+\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	3.2e-230	90.4
WP_014805830.1\|44302_45868_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_014805831.1\|46563_47307_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_014805832.1\|48418_49117_-	hypothetical protein	NA	NA	NA	NA
WP_014805833.1\|49113_49962_-	hypothetical protein	NA	NA	NA	NA
WP_014805834.1\|50249_51362_-	three-Cys-motif partner protein TcmP	NA	NA	NA	NA
WP_051053695.1\|51492_52278_+	phage Gp37/Gp68 family protein	A0A2P1A0W3	Gordonia_phage	1.6e-59	43.9
WP_014805836.1\|52569_53604_-	hypothetical protein	Q9G095	Leptospira_phage	1.3e-13	25.5
WP_014805837.1\|53603_54134_-	ImmA/IrrE family metallo-endopeptidase	Q9G094	Leptospira_phage	1.7e-17	40.4
WP_014805838.1\|54379_54925_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_014805840.1\|55478_55790_+	hypothetical protein	NA	NA	NA	NA
WP_014805841.1\|55792_56269_+	hypothetical protein	NA	NA	NA	NA
WP_014805842.1\|56265_56811_+	hypothetical protein	NA	NA	NA	NA
WP_014805843.1\|56807_58229_+	hypothetical protein	NA	NA	NA	NA
WP_014805844.1\|58788_59136_+	DUF2384 domain-containing protein	NA	NA	NA	NA
WP_014805845.1\|59132_59756_+	RES family NAD+ phosphorylase	NA	NA	NA	NA
WP_014805846.1\|59964_61233_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_158021586.1\|62099_62645_+	hypothetical protein	NA	NA	NA	NA
WP_014805848.1\|62789_63092_+	hypothetical protein	NA	NA	NA	NA
WP_014805849.1\|63072_63330_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014805850.1\|63759_65328_+	ParB N-terminal domain-containing protein	S5YZ97	Mycobacterium_phage	2.2e-76	39.2
WP_014805851.1\|65900_66182_+	hypothetical protein	NA	NA	NA	NA
WP_014805852.1\|66515_67019_-	hypothetical protein	NA	NA	NA	NA
WP_014805854.1\|68009_73850_+	relaxase domain-containing protein	NA	NA	NA	NA
WP_014805829.1\|74751_76071_+\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	3.2e-230	90.4
WP_051053697.1\|76951_78034_-	serine/threonine protein kinase	A0A1M7XUH0	Cedratvirus	9.6e-15	29.6
WP_014805856.1\|78389_79604_-\|transposase	IS110 family transposase	NA	NA	NA	NA
88988:89003	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_018027

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CRISPR-Cas detection and classification

Crispr_ID: NC_018027_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018027_1

1431927-1432038

Unclear

Consensus_repeat	Method
CCTCGCCGCTTGATCGTCACCCTCCGAG	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NC_018027_1

>merge|NC_018027|1|1431927-1432038|CRISPRCasFinder
CCTCGCCGCTTGATCGTCACCCTCCGAGTCTGATTGTCGGGCTCTCCCCCGCAAGCGGGAGGTGCCCCCACACCGCGGCTCGTTCCTCGCCGCTTGATCGTCACCCTCCGAG

>NC_018027|1|1|1431927-1432038|CRISPRCasFinder
CCTCGCCGCTTGATCGTCACCCTCCGAG	TCTGATTGTCGGGCTCTCCCCCGCAAGCGGGAGGTGCCCCCACACCGCGGCTCGTT
CCTCGCCGCTTGATCGTCACCCTCCGAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_018027.1\|WP_014814696.1\|1441842_1442697_+\|TIGR02569-family-protein	unknown	unknown	gnl\|CDD\|131620
NC_018027.1\|WP_014814690.1\|1435705_1436560_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237030
NC_018027.1\|WP_014814694.1\|1439249_1440461_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018027.1\|WP_014814695.1\|1440612_1441806_+\|adenylyltransferase/sulfurtransferase-MoeZ	unknown	unknown	gnl\|CDD\|181156
NC_018027.1\|WP_041781786.1\|1430424_1431036_-\|acid-phosphatase	unknown	unknown	gnl\|CDD\|139587
NC_018027.1\|WP_041781787.1\|1434997_1435702_+\|hydroxylase	unknown	unknown	gnl\|CDD\|205967
NC_018027.1\|WP_014814684.1\|1429330_1430428_-\|isochorismate-synthase	unknown	unknown	gnl\|CDD\|224091
NC_018027.1\|WP_014814679.1\|1424877_1426368_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226434
NC_018027.1\|WP_014814678.1\|1424615_1424831_+\|biotin/lipoyl-binding-carrier-protein	unknown	unknown	gnl\|CDD\|180306
NC_018027.1\|WP_014814681.1\|1428040_1428484_+\|type-II-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|235443
NC_018027.1\|WP_014814686.1\|1431117_1431921_+\|ParA-family-protein	unknown	unknown	gnl\|CDD\|379293
NC_018027.1\|WP_014814682.1\|1428480_1428891_+\|hypothetical-protein	unknown	unknown	unknown
NC_018027.1\|WP_041781788.1\|1437964_1438990_+\|DUF3152-domain-containing-protein	unknown	unknown	gnl\|CDD\|371483
NC_018027.1\|WP_014814680.1\|1427011_1427968_-\|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl\|CDD\|224513
NC_018027.1\|WP_051053575.1\|1428842_1429271_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_018027.1\|WP_014814697.1\|1442707_1443004_-\|DNA-methyltransferase	unknown	unknown	gnl\|CDD\|226219
NC_018027.1\|WP_003929142.1\|1426489_1426744_-\|WhiB-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376791
NC_018027.1\|WP_014814688.1\|1433247_1434729_-\|DEAD/DEAH-box-helicase	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|223587
NC_018027.1\|WP_014814691.1\|1436813_1437065_+\|DUF3107-domain-containing-protein	unknown	unknown	gnl\|CDD\|378634
NC_018027.1\|WP_014814692.1\|1437092_1437773_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
NC_018027.1\|WP_014814696.1\|1441842_1442697_+\|TIGR02569-family-protein	gnl\|CDD\|131620	TIGR02569, conserved_hypothetical_protein, TIGR02569 family protein. This protein family is found, so far, only in Actinobacteria, including as least five species of Mycobacterium, three of Corynebacterium, and Nocardia farcinica, always in a single copy per genome. The function is unknown. [Hypothetical proteins, Conserved].	4.76935e-129
NC_018027.1\|WP_014814690.1\|1435705_1436560_-\|hypothetical-protein	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	2.76759e-09
NC_018027.1\|WP_014814694.1\|1439249_1440461_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	4.40326e-39
NC_018027.1\|WP_014814695.1\|1440612_1441806_+\|adenylyltransferase/sulfurtransferase-MoeZ	gnl\|CDD\|181156	PRK07878, PRK07878, molybdopterin biosynthesis-like protein MoeZ; Validated.	0
NC_018027.1\|WP_041781786.1\|1430424_1431036_-\|acid-phosphatase	gnl\|CDD\|139587	PRK13462, PRK13462, acid phosphatase; Provisional.	1.61137e-134
NC_018027.1\|WP_041781787.1\|1434997_1435702_+\|hydroxylase	gnl\|CDD\|205967	pfam13794, MiaE_2, tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like.	4.694e-56
NC_018027.1\|WP_014814684.1\|1429330_1430428_-\|isochorismate-synthase	gnl\|CDD\|224091	COG1169, MenF, Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.14504e-123
NC_018027.1\|WP_014814679.1\|1424877_1426368_+\|sensor-histidine-kinase	gnl\|CDD\|226434	COG3920, COG3920, Signal transduction histidine kinase [Signal transduction mechanisms].	4.53689e-51
NC_018027.1\|WP_014814681.1\|1428040_1428484_+\|type-II-3-dehydroquinate-dehydratase	gnl\|CDD\|235443	PRK05395, PRK05395, type II 3-dehydroquinate dehydratase.	1.80029e-86
NC_018027.1\|WP_014814686.1\|1431117_1431921_+\|ParA-family-protein	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	4.62149e-77
NC_018027.1\|WP_014814678.1\|1424615_1424831_+\|biotin/lipoyl-binding-carrier-protein	gnl\|CDD\|180306	PRK05889, PRK05889, biotin/lipoyl-binding carrier protein.	9.16725e-25
NC_018027.1\|WP_041781788.1\|1437964_1438990_+\|DUF3152-domain-containing-protein	gnl\|CDD\|371483	pfam11350, DUF3152, Protein of unknown function (DUF3152). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently there is no known function.	1.79325e-124
NC_018027.1\|WP_014814680.1\|1427011_1427968_-\|diacylglycerol-kinase-family-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	6.51178e-53
NC_018027.1\|WP_051053575.1\|1428842_1429271_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	9.24872e-16
NC_018027.1\|WP_014814697.1\|1442707_1443004_-\|DNA-methyltransferase	gnl\|CDD\|226219	COG3695, COG3695, Predicted methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair].	1.17033e-27
NC_018027.1\|WP_003929142.1\|1426489_1426744_-\|WhiB-family-transcriptional-regulator	gnl\|CDD\|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	5.04294e-30
NC_018027.1\|WP_014814688.1\|1433247_1434729_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	2.96605e-154
NC_018027.1\|WP_014814691.1\|1436813_1437065_+\|DUF3107-domain-containing-protein	gnl\|CDD\|378634	pfam11305, DUF3107, Protein of unknown function (DUF3107). Some members in this family of proteins are annotated as ATP-binding proteins however this cannot be confirmed. Currently no function is known.	6.84945e-35
NC_018027.1\|WP_014814692.1\|1437092_1437773_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.08323e-17

>NC_018027.1|WP_014814686.1|1431117_1431921_+|ParA-family-protein
MGLVTRILAVANQKGGVAKTTTVASLGAAMVELGKRVLIVDLDPQGCLTFSLGQDPDKLAVSVHEVLLGEVEPDAALVETTEGMTLLPANIDLAGAEAMLLMRAGREYALKRALAKLADRFDVVLIDCPPSLGVLTLNGLTAADEVIVPLQCETLAHRGVGQFLRTINDVQQITNPDLKMLGALPTLYDSRTTHSRDVLFDVVDRYGLPVLAPPIPRTVRFAEATASGSSVLTGRKNKGALAYRDLANALLKHWKTGKALATYTPEV
>NC_018027.1|WP_041781786.1|1430424_1431036_-|acid-phosphatase
MGLLQHRLILLRHGETEWSKSGKHTSRTELDLTADGREQAKAAADTLVQMRLDDPYVVSSPRTRAKTTAELAGLQIDDVNPLISEWDYGDYEGTTTDEIRKAVPNWLVWTHGCPGGETSAEVCERADRAIELALEHMQTRDVVFVGHGHFSRAVITRWIEQPVYEGIRFAMPAVSIAVCGFEHGVRQLSALGLTGHPDPAAPT
>NC_018027.1|WP_014814684.1|1429330_1430428_-|isochorismate-synthase
MTREPSFVMAGPEGVVVAEGVQTAFPHIADARAALASHSTPMVVGALPFDVAAPAALLRPQSVRFTDALPAWPLRELAATRIAEMTPDADEHRRRIAAALERLRDPAGGLQKVVLARALRLAADGPLDARTVLHRLAADDVQATKYLVDLSAAGDGYSGAALIGASPELLVARQGLQVTCRPFAGSAPRHRDPDADAASGAALADSAKNRHEHQLVVEALRDALDPLCTDLQVAEHPQLTKTAAVWHLYTPISGRLREKSTTALDLAVALHPTPAVGGSPTDRAVALIDEIEGDRGFYAGTVGWCDQRGDGRWVVSIRCAQLSADRRTAVAHSGGGIVAESDPDDEVDETTTKFKTILSALGVAP
>NC_018027.1|WP_051053575.1|1428842_1429271_-|GNAT-family-N-acetyltransferase
MIHELAAFERASAECTVTEDQLREALFGSAPTVFGHIAEVDGRAAGGALWFRNFSTWDGVAGIYLEDLFVRPDFRRRGLARRLLATLARECVEHGYSRLTWAVLDWNVDAIALYDSVGGRPQTEWITYRVSGSELSELAESG
>NC_018027.1|WP_014814682.1|1428480_1428891_+|hypothetical-protein
MTPRAVRIAGGIAVAQGTLAIVMAVVLTVRELAGHREVAISGYGTAVWFVIMGSAVIAAGWALWTGRRWGRGIAVFANLLLLGVAWYVFSSGQLLYAVAVAAVSVAVLALLFSPPVLHWLGHPDSASSESSEPETR
>NC_018027.1|WP_014814681.1|1428040_1428484_+|type-II-3-dehydroquinate-dehydratase
MTERRLLLVNGPNLNLLGTRQPEVYGATTLAEIEARVSEVAKESGLKVRAVQSNHEGALVDAIHAARTDCAGIVINPAAYSHTSVAIADALRSVGLPVAEVHLSNIHAREEFRHHSYVSAVADMVVAGAGPLGYEMAVRYLADRLTP
>NC_018027.1|WP_014814680.1|1427011_1427968_-|diacylglycerol-kinase-family-lipid-kinase
MRAVLIVNPNATSTTAAGRDLLAHALESRVSLTVAHTDHRGHAIEIARDAARDGVDVLIVHGGDGTVNEVVNGIMDEVGPGGAAPAVGVVPGGSANVFARALGISPDPLQATNQLVDLLSEYRRTGIWRRIGLMDCGERWAVFTAGMGVDGDVVAAVEAQRAKGRKVTASRYIRVAIREVLASARKEAALTLHLPGREPVPGVHFVFVSNASPWTYANTRPVWTNPDTTFEGGLGVFATTSMNVWANLRLVRQMTSRKPRLDAKHLIRDDDLPWLKVTSARPVACQIDGDFVGERETMQFTAVRDALSVVAPPPNSAQ
>NC_018027.1|WP_003929142.1|1426489_1426744_-|WhiB-family-transcriptional-regulator
MDWRHKAVCRDEDPELFFPVGNSGPALAQIADAKLVCNRCPVTAECLSWALESGQDAGVWGGMSEDERRALKRRNARTKARTGV
>NC_018027.1|WP_014814679.1|1424877_1426368_+|sensor-histidine-kinase
MSTLGDLLAEHTILPGSAVDHLHAVVGEWQLLADLSFADFLMWVQRDDGKLVCVAQVRPNTAPTVLLADAVGTLAGPRDVPIVAAAFRSGVIGRATIDGLDGSPGLKVEAVPVRHDSAVVAVLTHQMSLAPRQASPLEAAYVDCAGDLLHMLSEGTFPNVGDLAMSRSSPRVGDGFIRLDEAGVVSFASPNAISAYHRMGLTAELEGHNLVSVTRPLISDPFEAQELANHVRDSLGGGSSMRMEVEAGGAAILLRTLPLVVHGSAVGAAVLIRDVTEVKRRDRALLSKDATIREIHHRVKNNLQTVAALLRLQARRTNNAEGREALIESVRRVSSIALVHDALSMSVDEEVNLDEVVDRILPIMNDVASVDAPIRINRVGELGVLDADRATALIMVITELVQNAIEHAFDATTAAGCVTIRAERSARWLDVVVHDDGRGLPAGFSLEKSDRLGLQIVRTLVSAELDGSLGMHDVPTGGTDVVLRVPIGRRLRASQF
>NC_018027.1|WP_014814678.1|1424615_1424831_+|biotin/lipoyl-binding-carrier-protein
MAEDVRAEIVASVLEVVVSEGDQIGAGDTLVLLESMKMEIPVLAEVAGTVSQVSVSVGDVIQAGDLIAVIS
>NC_018027.1|WP_014814688.1|1433247_1434729_-|DEAD/DEAH-box-helicase
MTPVTQHPTFAELGVRDEIVRALADNGIEHAFAIQELTLPLALAGDDLIGQARTGMGKTFAFGVPLLHRITTDTERPLTGIPRALIVVPTRELCLQVYGDLVGASKYLMADDTRKLTVTAIYGGRPYEPQIEALQKGVDVVVGTPGRLLDLAQQGHLQLGGLSTLVLDEADEMLDLGFLPDIERILKQIPAQRQAMLFSATMPDPIITLARTFMTQPTHIRAEAPHSAATHDTTEQFAYRAHALDKVEMVSRILQAEGRGATMIFTRTKRTAQKVADELSERGFKVGAVHGDLGQGAREKALKAFRTGEVDVLVATDVAARGIDIDDITHVINFQIPEDEQSYVHRIGRTGRAGKTGIAVTLVDWDELPRWSMIDKALGLDTPEPAETYSSSPHLYEELNIPADAGGSIGRARSASATKSSRQRSTEDNGDRPAKRSTRTRRRTRGGQTVSGHPESAEQATPAESDGGESADAARPARRRRRRRPSKAPAGTS
>NC_018027.1|WP_041781787.1|1434997_1435702_+|hydroxylase
MTSTPSAAAASAPTGGSSAPAVTPDHPGVNELFALLAYGEVAAFYRLTEEARMAPNLRGRINMASMAAAEMNHYEVLRDALERRGVDVVPAMTRYASALENYHRLTTPSTWLEALVKTYVGDALAADFYLEIADSMPDAVADVVRSVLSETGHSQFVVAEVRAAVTASDRQRHRLALWSRRLLGEAITQAQFVLADHDELVDLVMSGGGLSQMTDFFDRLQNTHSSRMQELGLA
>NC_018027.1|WP_014814690.1|1435705_1436560_-|hypothetical-protein
MNRPYTAQSPYSLTPTERMRSSRRSGRSSGRYGGRYGDDAGYEGYGTDGRYGDLDTDVYPPYPGYDEPAEDYDEAVEMYDEARIDRRWMWIAGVAGAILFVAVITASMILGGGDSGSVSATLSQDGASGEPTTTAAAAPSAAPTSAPRAAAAPPSPSLPAETVTTITPTAQTPTPAPAVPVLPAPQAAPPAPAAAPGTITYHITGNKQLIDFVTVIYTDQRGALQTEMNVSLPWSKTVVLDPGVTLSSVTATSVGGQLNCSISDANGAVIAAQNSNSMITNCTR
>NC_018027.1|WP_014814691.1|1436813_1437065_+|DUF3107-domain-containing-protein
MEVKIGVTDSPRELILSSAQTPAEVEKLVTDVLDAGTGVLALTDEKGRRYLVQSARIAYVEIGAADARRVGFGVGIDTAKSAG
>NC_018027.1|WP_014814692.1|1437092_1437773_-|TetR/AcrR-family-transcriptional-regulator
MSELARTAQRRGGQPANGTGLPSASAARRGNRLPRDERRGQLLVAASEVFVDRGYHAAGMDEIADRAGVSKPVLYQHFASKVELYLAVLQRHVDNLVSGVRQALRTTTDNRQRVRAAVAAFFDFIEHDGQGYRLIFENDYVTEPQVAAQVKVATESCTDAVFDLISHDSGLEPHRARMIAVGLVSISVDSARYWLNNERPIAKDDAVEGTVQFIWGGLSHVPLTRS
>NC_018027.1|WP_041781788.1|1437964_1438990_+|DUF3152-domain-containing-protein
MTYDPGRHGGVPVLRDEWREPLRAQRDPLADQPGRVRSNRDDHKRWRKQTWIGRFVSTYGWRAYALPLLAVLTAVVLYQTMTGTSVAPAPRDEGPVQGPPTIGAASKAIVGAPPKGLTQFDANLPTGILPQGGPFTEAGARTWHVVPGTTQQVGQGTSKIFTYTVEVEDGVDTTSFGGDEGFARMVDETLANPKSWTHNPQFAFTRVDANSGVQPDFRVSLTSPMTVRQGCGYDIQLEASCYNPAYGDQPRVFINEARWVRGAVPFQGDIGSYRQYVINHEVGHAIGYPRHEQCADNGDLAPVMMQQTFSTSDNDAARFDPGTVTADGKTCRFNPWPYPIA
>NC_018027.1|WP_014814694.1|1439249_1440461_+|IS110-family-transposase
MIFVGDDWAEDHHDVYLMDEAGQRLAARRLPEGLSGIRALHELIAVHADQPDQVLVGIETDRGLWVSALAAAGYQVWAINPMAAARYRDRHHVAGAKSDAADAKLLADLVRTDRHNHRQIAGDSPDAEAIKVLARSHQSLIWARTRHANMLRSALREYYPAALEAFDALTDGDALAILGRAPTPEQGAQLSLAKIGSALKAAGRQRNIEARAAEIQAVLRRKHLTAPPAVAAAFGATTTAAVHVIAALNTQIADLETALADHFETHPDADIYRSLPGLGVVLGARVLGEFGDDPNRFTTAKCRKNYAGTSPLTIASGRKRAVLARHVRNKRLYDAIDQWAFCALLRSPGARTYYDEHRAAGDTHHQALRALGNRLVGVLHGCLRHHTRYEEHKAWAHRQTAAA
>NC_018027.1|WP_014814695.1|1440612_1441806_+|adenylyltransferase/sulfurtransferase-MoeZ
MSTPLPPLVEPAAELNREEVARYSRHLIIPDLGLDGQKRLKNARVLVIGAGGLGSPTLLYLAAAGVGTIGIVEFDVVDESNLQRQIIHGQSDIGRSKAESARDSILEVNPLVDVRLHEMRLEPDNAVELFEQYDLILDGTDNFATRYLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAPADEGGNERGLNYRDLYPEPPPPGMVPSCAEGGVLGILCASIASVMGTEAIKLITGIGEPLLGRLMVYDALDMTYRTIKIRKDPSTPKITELIDYEEFCGVVSEDAAEAAREATVTPRELQELLESGKKYALIDVREPVEWDINHIEGAELIPKSTIESGDGLAKLPQDRVPVLYCKTGVRSAEALAVIKKAGFSDAMHLQGGIVAWAKQLEPDMVMY
>NC_018027.1|WP_014814696.1|1441842_1442697_+|TIGR02569-family-protein
MTAERPPEHVLTAFGLSGVQPVPLGSSWEGGWRCGEVVLSMVADHARAAWSAKVRETLFVDGVRLARPVRSTDGRYVVAGWRADTYVAGTPEPRHDEVVSAAVRLHEATAKLERPRFLTQPPIAPWADVDVFIAADRAAWEERPLHSLPPGARVSPGTSDGQKSIELINQLASLRRPTKSPSQLVHGDLYGTVLFAGTAAPGITDITPYWRPPAWAAGVVVVDALSWGEADDALIERWDTLPEWPQMLLRALMFRLAVHALHPRSTAAAFPGLARTAALVRLAL
>NC_018027.1|WP_014814697.1|1442707_1443004_-|DNA-methyltransferase
MAPITDEHVETVRGLVAAIPAGKVATYGDIADAAGLSSPRIVAWIMRTDSSDLPWHRVIRASGRPAPHLASAQLERLRAEGVLATDGRVPLSGCRHRF

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Crispr_ID: NC_018027_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018027_2

1496067-1496143

Orphan

Consensus_repeat	Method
CTGGCTTCCTTGCGGGCCTGGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_018027_2

>merge|NC_018027|2|1496067-1496143|CRISPRCasFinder
CTGGCTTCCTTGCGGGCCTGGCGAGCCGCCGCGGCGTCGGCCTTGGCGGCAGCTCTGGCTTCCTTGCGGGCTTGGCG

>NC_018027|2|2|1496067-1496143|CRISPRCasFinder
CTGGCTTCCTTGCGGGCCTGGCG	AGCCGCCGCGGCGTCGGCCTTGGCGGCAGCT
CTGGCTTCCTTGCGGGCTTGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_018027.1\|WP_014814746.1\|1500890_1501241_-\|hypothetical-protein	unknown	unknown	unknown
NC_018027.1\|WP_041782702.1\|1491032_1491926_-\|L,D-transpeptidase	unknown	unknown	gnl\|CDD\|240446
NC_018027.1\|WP_158021329.1\|1505646_1506723_-\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|366009
NC_018027.1\|WP_158021439.1\|1501579_1504369_+\|cellulase-family-glycosylhydrolase	unknown	unknown	gnl\|CDD\|375990
NC_018027.1\|WP_014814740.1\|1494701_1495103_-\|heme-binding-protein	unknown	unknown	gnl\|CDD\|377163
NC_018027.1\|WP_014814735.1\|1489697_1491002_+\|carboxylesterase-family-protein	unknown	unknown	gnl\|CDD\|365897
NC_018027.1\|WP_041782704.1\|1491982_1492435_-\|thioredoxin	unknown	unknown	gnl\|CDD\|200072
NC_018027.1\|WP_014814738.1\|1492590_1493025_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_018027.1\|WP_158021328.1\|1498773_1500345_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NC_018027.1\|WP_014814733.1\|1488005_1488740_-\|hypothetical-protein	unknown	unknown	unknown
NC_018027.1\|WP_014814739.1\|1493025_1494705_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NC_018027.1\|WP_014814753.1\|1511448_1512795_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293810
NC_018027.1\|WP_014814748.1\|1504392_1505634_-\|MgtC/SapB-family-protein	unknown	unknown	gnl\|CDD\|225715
NC_018027.1\|WP_158021440.1\|1510030_1511428_+\|phenylacetate--CoA-ligase-family-protein	unknown	unknown	gnl\|CDD\|224458
NC_018027.1\|WP_014814741.1\|1495153_1495582_-\|PPOX-class-F420-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274679
NC_018027.1\|WP_014814734.1\|1488995_1489610_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_018027.1\|WP_162131300.1\|1497897_1498731_-\|DUF1906-domain-containing-protein	unknown	unknown	gnl\|CDD\|378098
NC_018027.1\|WP_014814750.1\|1506812_1509413_-\|cation-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319775
NC_018027.1\|WP_041781794.1\|1500351_1500633_-\|hypothetical-protein	unknown	unknown	unknown
NC_018027.1\|WP_014814732.1\|1487244_1488009_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_018027.1\|WP_158021439.1\|1501579_1504369_+\|cellulase-family-glycosylhydrolase	gnl\|CDD\|375990	pfam18564, Glyco_hydro_5_C, Glycoside hydrolase family 5 C-terminal domain. This is the C-terminal domain of endo-glycoceramidase II (EGC), a membrane-associated family 5 glycosidase pfam00150. The C-terminal domain assumes a beta-sandwich fold, which resembles that of many carbohydrate-binding modules.	9.57449e-13
NC_018027.1\|WP_041782702.1\|1491032_1491926_-\|L,D-transpeptidase	gnl\|CDD\|240446	cd13431, LDT_IgD_like_1, IgD-like repeat domain of mycobacterial L,D-transpeptidases. Immunoglobulin-like domain found in actinobacterial L,D-transpeptidases, including Mycobacterium tuberculosis LdtMt2, which is a non-classical transpeptidase that generates 3->3 transpeptide linkages. LdtMt2 is associated with virulence and resistance to amoxicillin. This domain may occur in a tandem-repeat arrangement and is found N-terminal to the catalytic L,D-transpeptidase domain; this model represents the first (N-terminal) repeat in LdtMt2 and related proteins.	1.85894e-27
NC_018027.1\|WP_158021329.1\|1505646_1506723_-\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|366009	pfam00296, Bac_luciferase, Luciferase-like monooxygenase.	8.27568e-41
NC_018027.1\|WP_014814740.1\|1494701_1495103_-\|heme-binding-protein	gnl\|CDD\|377163	pfam03928, Haem_degrading, Haem-degrading. Haem_bdg is a bacterial protein that is up-regulated in response to haemin- and peroxide-based oxidative stress. It interacts with the SenS/SenR two-component signal transduction system. Iron binds to surface-exposed lysine residues of an octomeric assembly of the protein.	2.99128e-30
NC_018027.1\|WP_014814735.1\|1489697_1491002_+\|carboxylesterase-family-protein	gnl\|CDD\|365897	pfam00135, COesterase, Carboxylesterase family.	2.05156e-83
NC_018027.1\|WP_041782704.1\|1491982_1492435_-\|thioredoxin	gnl\|CDD\|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	1.22189e-37
NC_018027.1\|WP_014814738.1\|1492590_1493025_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	9.6243e-16
NC_018027.1\|WP_158021328.1\|1498773_1500345_+\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	6.82852e-55
NC_018027.1\|WP_014814753.1\|1511448_1512795_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293810	cd07724, POD-like_MBL-fold, ETHE1 (PDO type I), persulfide dioxygenase A (PDOA, PDO type II) and related proteins; MBL-fold metallo-hydrolase domain. Persulfide dioxygenase (PDO, also known as sulfur dioxygenase, SDO, EC 1.13.11.18) is a non-heme iron-dependent oxygenase which catalyzes the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria. Mutations in ethe1 (the human PDO gene) are responsible for a rare autosomal recessive metabolic disorder called ethylmalonic encephalopathy. Arabidopsis thaliana ETHE1 is essential for embryo and endosperm development. Bacterial ETHE1-type PDOs are also called Type 1 PDOs. Type II PDOs (also called PDOAs), are mainly proteobacterial. These enzymes belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	2.02012e-61
NC_018027.1\|WP_014814739.1\|1493025_1494705_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.93036e-42
NC_018027.1\|WP_014814748.1\|1504392_1505634_-\|MgtC/SapB-family-protein	gnl\|CDD\|225715	COG3174, COG3174, Predicted membrane protein [Function unknown].	3.29317e-45
NC_018027.1\|WP_158021440.1\|1510030_1511428_+\|phenylacetate--CoA-ligase-family-protein	gnl\|CDD\|224458	COG1541, PaaK, Coenzyme F390 synthetase [Coenzyme metabolism].	6.61173e-44
NC_018027.1\|WP_014814741.1\|1495153_1495582_-\|PPOX-class-F420-dependent-oxidoreductase	gnl\|CDD\|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	3.03758e-27
NC_018027.1\|WP_014814734.1\|1488995_1489610_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.06085e-11
NC_018027.1\|WP_162131300.1\|1497897_1498731_-\|DUF1906-domain-containing-protein	gnl\|CDD\|378098	pfam08924, DUF1906, Domain of unknown function (DUF1906). This domain is found in a set of uncharacterized hypothetical bacterial proteins.	3.13963e-43
NC_018027.1\|WP_014814750.1\|1506812_1509413_-\|cation-translocating-P-type-ATPase	gnl\|CDD\|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0

>NC_018027.1|WP_014814741.1|1495153_1495582_-|PPOX-class-F420-dependent-oxidoreductase
MSQSPLSESAKEMLAKANPAVISTVRSDGQPVSAATWYLLRGDRVLVNMDQGRKRLEHLRNDPRVSLTVLDEADWYTHVTIIGRVAQMYDDEDLADIDALSRHYTGQEYPQRDRPRISAWIEVDRVHGWGSQKNNDQPDGRQ
>NC_018027.1|WP_014814740.1|1494701_1495103_-|heme-binding-protein
MTVDLATAVRMIAAAHAEAEKRSILVSAAVVDAGGHLVAFGRMDGAEIAGPVLAVDKAYTSVANRIATSELATLAAPGGDLFGLHTSGGGRFVIFGGGVPVTIDGVVVGGVGVSGASAAEDEACALAALRCLG
>NC_018027.1|WP_014814739.1|1493025_1494705_+|MFS-transporter
MTVDERKARTGDNYRWVALTNTTAAVFMSALDGSIVIISLPAIFRGIDLDPLAPANIAYLLWMIMGYRLVQSVLVVTLGRIGDMFGRVRVYNFGFTVFTFASIMLSFDPFHGAAAAQWLIGWRLLQAVGGSMLTANSAAILTDAFPPDRRGFALGFNQVAALGGQFIGLVAGGLLAAWDWRAVFWVNVPVGIFGTVWAYRRLRDNGERHRGRIDWWGNITFAVGLSAVLIAITSGIQPHGDQPTGWNSPFVLGTLTAGVVLLIAFVVIESRVAEPMIRLSLFKIRAFSAGNAAALAAALAQGGLQFMLIIWLQGIWLPLHGYDYAETPLWAGVFLLPLTAGFLVAGPTAGSLSDRFGARGIASAGMALFGLSFVGLLLLPIDFSYWAFAVLIALNGVGSGMFSAPNTSAIMSSVLPGERGVASGMRATFQNSGTALSIGVFFSLMIVGLAASLPGSLSSGLTAQGVPPPVAQQVASLPPVSTLFAAVLGVNPLEHLLEPSGVLTQLPPGNRDAITGREFFPHLISGPFHHGLGVVFGVSIALAVLAGIASLARGRVDRP
>NC_018027.1|WP_014814738.1|1492590_1493025_+|MarR-family-transcriptional-regulator
MRPGPDPEAVARALFLCMGLLRRRLRQTPTGDVLTFPQIAALSRLDRSGPATGADLARQEQISPQSMGATLGELEARGFITREQDPTDGRRILLSISAAGKREVTRRRSARVEQIAAGLVDFTDAELEQLAAAAPLIERLAYHL
>NC_018027.1|WP_041782704.1|1491982_1492435_-|thioredoxin
MQTTNVKCAECGQVNRVPAAASGTPRCASCHQPLPWIAVAGDRDFTDIVEKSKVPVLVDLWATWCGPCRMVSPALEQLARERAGRLKLVKVDVDAAPQIAARFSVQAVPTLLVTKGGTVLARQSGAAPVAALRTWLDQALAADSSAQSQS
>NC_018027.1|WP_041782702.1|1491032_1491926_-|L,D-transpeptidase
MSGWTRTHLIDAVKAAGVAFIAGCALALSAGPAVAEPAPGDPGIVVSGPAAGQDPTPFTGVAPFGPPKVLPGNGATVGVAQPIIVNFPGLVDDSGAAERAVHVSSVPPVPGKFYWMTPTQLRWRPLSFWPAHTAVTVDAGGAVSSFQTGDSLVATADDATHQLTITRNGAVEKTIPMSMGMSAGGHQTPNGTYYVQEKMPSVVMDSSTYGVPVNSTYGYRTTVELAVRFDDSGDFVHSAPWSVGDQGKRDVSHGCINISPSNAKWFFDNFNAGDPIVVKNSSGGTYSRHDGSNDWQL
>NC_018027.1|WP_014814735.1|1489697_1491002_+|carboxylesterase-family-protein
MAHRVVDASCGPLLVHDDGTLITARGIVYATAERFTAPVPAPTHSDVHDATRRGPACPQLRSRLEFVTGPVVDGLARSEACQVLSVTAPCDAQGLPVMVWFHGGAYMSGGGEAPKYDPDAVAADGRVVVVSVTYRLGIFGYLNPCAGGDGNLGLRDQIQALRWVQRNIAAFGGDPAQVTIFGQSAGGDSVFSLVLSEETTGLFHRAILQSAPLGLRRGREAMTAAMRAAVVDALDDAEPEEAGVERLLEAQTVAVAAAQRFGLIGGLPFAPIEGLDPLPPGATTNRRLAEVARQVEILVGYTRDDAAPFVAMDPRGRRLRRLGLPGRRLGRLAGARMTNRIFGQPARDLAELWTSHGGRAATFRVDWSPPGAPLGACHCIELPLLFSAQRWADAPMLGSRPDPVDTDLAGRVRGYWAAFAHGGVSGLENPTLRI
>NC_018027.1|WP_014814734.1|1488995_1489610_+|TetR/AcrR-family-transcriptional-regulator
MLHNGGVPNSATQREVQRRNTRARLLDAAIVEFQRAGTGSADINAIVKAAGVARSTFYFHFPTKEHVLLELIRRDEQHLAEELARFLETRHDLPTVLTTIIELVLDLESRWGSALFHDVIRLFFSNRPEREQWINHPIFVLLAAEIERARIRGELYDDVDAYHSAAFFLLGVYALLTTVGESRSERDVALKKFVTSTLRSLQPV
>NC_018027.1|WP_014814733.1|1488005_1488740_-|hypothetical-protein
MTTTTPTSTAMNTRGQRILLWTVPPAAALFVVAYFLFPVFSPPLSPTMTPEQVGAFFTDNVTGILGVAILCNLIACSLVPLFAVAAVQMSRIGTSSNVFTYAYILCVGVGLTAFILADYCWGMAAFRPERNPQLISLLNDMAWFFFIAPVGPIIVANLCLAISIYLDTRPDPIFPRWVAHFNIAVAVLLVPSAFSLLHKSGPLAWNGALSFDLRLIVLACYIVVMFLVLLGVIHRQGEEREALI
>NC_018027.1|WP_014814732.1|1487244_1488009_-|hypothetical-protein
MTVMAGWRKSKKLDQWIAFWSVPVFFSLFGLVFVPLSWMMPPRSPSSPQAEIVAFMQSPNLLVACVILTLAFGLAPVSNACYLNQIRRMSVSPVLRYSLMAGAMTGTIVGMLFPMFCFGLGAFRPGYDPAILAMLYDFGYLAFIGSLGCFCIMWMAFGLAIILDQNHILPKWLGYYTVWQYVTELMAAPVWIAKSGPFAWNGVMTFWFAMALYVPWQMIVYLCIYRAIKNQPDDELDNAFLESDLAATRSKASA
>NC_018027.1|WP_162131300.1|1497897_1498731_-|DUF1906-domain-containing-protein
MATGARHLCCYHRAVHDPSSGRGGHQQVSRRQALRYAVAAPVLLNVATAFAPSASAAGPRLIDFTERLVRPDQIKSAGFAGALVYVSEVRPGADFDFKPVTREYADAMRANGLHIVSCYQYGKPGWPTPSDFTRGFDGGVADAQTALRLHDAAGGPDSAPIFFSVDEDIDLQTWKSPAVEWLRGIGSVLGVERTGIYGHSRACGWAIGDGVIGHSSSAGYRWAWQTSAWSQGEREPAAVLYQSAVNTASTPGPLIGGIHVDVDDVLAADFGQWDLKR
>NC_018027.1|WP_158021328.1|1498773_1500345_+|serine-hydrolase
MHCGSISTPHATTARRWARLGMVLGTVVVTFAAPCPRGVEARAAVIPAPHATAARAHTTPPPPAPDLPPTPDIAAVSALIDDAVAAHRLPGAVVVVGHAGKVAFHRAYGSRKLAGEPGLSGSPSPAEPMSENTIFDMASMTKVLATATAVMQLYEQGRVQLDRPVQTYLPEFNTANDPQRTRVTVRMLLTHTSGLPEDVNLDDPWGLGNADKREGIRRALTAPLQSEPGANFHYADINFLVLGALIERLTGTPEDVYVQQNVFEPLGMNDTRYLPVGKACGPHIVRGAAIAWAPTGNTTCSADTWNSDLLSRVAPTRHDGEGGRDPAKNPDFGQLVRGTVDDPTARRMGGVAGHAGVFSTARDVSIFAQALLDRLAGRPSAFPLKQVTLVTMTTPQQPGHTDQQVGTANQAYREILVQAGDSRTRLLAPRYPAIRGQALRGLGWDIDTGYSMPRGAIFPVGSFGHTGFTGTALWIDPASDTYVVLLSNAVHSPGSPPVLRLAGEVATAAARELGVDSAGPRRP
>NC_018027.1|WP_041781794.1|1500351_1500633_-|hypothetical-protein
MKRSMMFLASTAAAASVLLSGCSGVTNKGGDTTCKDFQGADEKSQNESITKMLKDEGKNEPSNAELTGTRLSITTFCQTAGKQDSTIKEAPHL
>NC_018027.1|WP_014814746.1|1500890_1501241_-|hypothetical-protein
MKFARTAAKAAVIAALGAGACGIGAGIAQADDHGWQPPWPGPGVNVGWPGNPLPPGHDGFPPPGHRGWHSEDNDDQGGHGRVWAPPPPPWAPWAPVIWDGNSQRWGVVVGGVFVGI
>NC_018027.1|WP_158021439.1|1501579_1504369_+|cellulase-family-glycosylhydrolase
MLGVGGAVVAGGGTAWADEGTVSHSATHTSATRSADATSGNPAPRGRSAAGPKKLARQHLSTPTSDAAADGDESGRSHVATDEASAEVSTHRRVRDSSRASTTANPVAGPARSARTRPRVRAAEPAPAVATATEPAPAPRLPDEPGPPSPGVTLSQEGPTQASHSARPLPAVVEFAAQHRNHRSTPVPGDSPATPAVASAVWLTAAAARRERGASEVPDAAAAGAAPPALIAPASPSSRPSSYDLPSLFRDVVFAPIHAAVQFWITSDLGRLVDGVINAVFGSYVIGNGSPGTAEDPDGGAAGWLLGDGGAGWNSTEDGHAGGDGGAAGLLGVGGAGGSGGVGAAGGDGGTGGRLLGIGGAGGRGGAGADGGAGGDAAALVLGIGGRGGDGGDGAQGGRGGNGGDGAAFLGSGGDGGDAGLSGIGGASTGLPALGGAGGTAGALGTHGDVGRSGRIVDGPASAGTAGSLSPVSTTGTWLTNSDGQVVILHGLNEVYKVAPYEPSASGFAADDAAFLAANGFTVVRLGIIWSAIEPEPGVYNTAYLASIDQTVQTLAEHGIYTIIDMHQDNYSEEFQGEGAPLWASDGGGRPNPSNGFPGNYFTNPAEQHAWDVFWDNAAAADGLGLQDHVTQTWQQVAAYFSGNTDIIGYEVINEPFSGSSWPADVLGSRFFGHQQLTPFYNQVIAAIRSVDSVTPVWIEPGNPAISEIPTVLGLPVRLGTIDDPNTVLSYHGYSGGIPVIGGFIVGRLASASRQYANRHDMPVFLTEFGATNDTSVITTEMRAGDRIRAGWVEWAYSGVGDVTGSPEVEWLVRDPAAAPVGDNVNAATLTTLAEPYAQTISGTPVSYAFADGTYDLTYSTERADGSGRFEPGARTYVSVPDLAFPDGYVVTVSGGQVVSAPDARILVIASGAAADTVHVVVSAAPAGG
>NC_018027.1|WP_014814748.1|1504392_1505634_-|MgtC/SapB-family-protein
MSLQQIQPFLVALAIGLLLGLERERSHSRKLPAGSRSFALLSLLGAVAASVDEWVVVVGLVSVAALVALAYFRTSEDDPGTTTAIAALGAYLLGVLAYTRPAVAVALAVVVAGLLLSKSRIHRFAREIVSEVEVEDAIKFLVVAFVILPLFPDRALGPYGVLNPAKVWLLVVLLTGIGWIGYIGVRALGPQRGLLITGLAGGFISATATTASMGRLGRTANSVSAPLASALLASLATFVQLLLVIGVVDADVLRRLWPPVVAGAAVLVGIAAFVYRRAAPDEQSERQQPTQGSRPFALRPALILTAVLTFALLIGRWGSDVLGPQGTVLAAFAAGLADAHAGSIAATSLAARGDITVDTALVAIAAALGSNMIVKTVLAFTAGGRRFGLGFLVGMGAPTVVFGVAMFAAVSAG
>NC_018027.1|WP_158021329.1|1505646_1506723_-|LLM-class-flavin-dependent-oxidoreductase
MTLDSVMVIDHFQNVFPTSIWDRDLTWLAAQRDTPHEFFDYQVLAGYLASRVGRMRLGVGVTEAIRRHPVLIAQAMMTLSHLTARAPILGIGAGERMNLDPYGFDAAEPVSRLEEALQIIHLCFSTQGPIDFCGRHFQLHSAPMDLKPARGRVPEIWVAAHGPRMLSLAGRWGDGWYPATVVSPREYAEKLAAVRAAAVAAGRNPAAITPALHRFMVVAPSEREARAMLDTKVVRAFALMAPPSLWRQAGVDHPFGERFNPLVDFVPGRYDRETMNAAIAAVPSAVVAEGPLLWGSRNQVVARLRAFGEAGLRHVVLAPVSGLVSPRAALYSLWATGRIARSLRRTSPGDGTSAPLLC
>NC_018027.1|WP_014814750.1|1506812_1509413_-|cation-translocating-P-type-ATPase
MTLDGSVAGLTSDQAARRLAADGPNELPTAKRRRLIQEAWAVVRQPMLLLLLAAGLVNFLLAEPLDGALLMAFVVVVIAISIYQEHKTEKALAALRDLSSPRALVVRDGAQVRIAGRDVVRGDLLLLAEGDRVPADAVLVDSANFSVDESALTGESVPVRKVAVEPAEVSAELGRPGGDATPWIFSGTLVVKGHGAAVARATGAVTELGKIGAALRTIEPERTALQREIDRLVTVLASLGAAAAFAVVVVYGLTRGDWLAGTLAGIATAMALLPEEFPVVLTVFMAVGAWRMSKRHVLTRRPPVVETLGSATVLCVDKTGTLTLNRMTVRTLIVDDRTHVCDDQPLPEEFHAIAEYSVLASPVDPFDPMDKAFKELGDSYLRETPHLHGDWQLVREYPLSEKLLALAHVWRSPDGNQYVVAAKGAPEAIADLCHFDRTRLAALTEDVEAATADGQRVLAVARARFDAASALPAQQHDFDFEFLGLAGLYDPVRPGVADAVAECRRAAIRTIMITGDYPGTALAIAREIGLDHTAGCVTGRQLQAMSDDELADRVRSVSVFARMVPEQKLQLVRALQADGEVVGMTGDGVNDAPALRAADIGIAMGAHGTDVARESAALVITDDDFTSIVGGVRQGRGIFDNLRKAMAYVIAVHLPIVGMSLIPLFVTDWPLVLLPVQIAFLELIIDPACSVVFEAEQIDPNIMDAPPRSRAEPMFGARVLGIAALQGLSLLATTAGVYIWAVLTDRPDSVARSVTFTALVVGNLALILVNRSWRLPVWQTIRQRRNSTLKWILGGATLLLIAMLTLPALRAAFGFGALTWGECGAAVAAGVVAVAWFEIYKAVSARDRSRVSVRADDRTDVDAVAR
>NC_018027.1|WP_158021440.1|1510030_1511428_+|phenylacetate--CoA-ligase-family-protein
MYGTRREGTGGVARRQNRRLRDVVAYARTHSSYYRDLYREVPQDFSDVEQLPVVTKADLMDHFDRWVTDPSVTRTRVETFLADPANLGVDFLGRYVACTTSGATGVPAILVHDHRALFVYNVLGYVRALPPALSSTRHIGAVLRPRVRLAAVFVTGGPFLGNTMMARRLRKLPWRSATQRLFSALTPLDELVDALNDFDPAVLGGYPSALDALAGERRAGRLRIHPVVVNAAGETLTPPVRQRISAAFDCHVTNYYGSSEAIGLTYECGAQNLHVNSDWHILEPVDEDNRPVAAGQLSDGVLVTNLANRIQPIIRYQMGDRVAIQPESCPCGSAFPWIRVVGRTDDVLTFAGAQGRGIRILPLAIASVAEETPGVAICQLIQRGPSELHVRLGVRPGSSEPVVWAELHRRLQGFLADHAIMTVRITKSDDAPALHPRSGKFRQVYRDFTDVTQHEREYDSAARRR
>NC_018027.1|WP_014814753.1|1511448_1512795_-|MBL-fold-metallo-hydrolase
MKVTIIDTSGLGDRSYLVSDSGIAVVIDPQRDIDRVLDLARELQVRITHVLETHLHNDYVTGGLELARTTGAEYVVASGDDLGYERRAVSDGDVVDVGPFSLAVVHTPGHTYTHVSYVLRDAAGTAAGVFTGGSMLHGTTGRTDLLGEEHTDALTHAQYRSVRRLAEELPDDVQVYPTHGFGSFCSATPAAGDESTVADERRTNPALTQSEQAFVDELIAGLGAYPAYYAHMGVINAEGPAPVDLSMPEPVDPAEVRRRAEAGEWVVDLRNRKAFAAAHLAGTLGFELSTPFVTYLGWLYTWGAPLTLIGDDKEQILQARRELARIGIDRLAGSAVGAISALADGTPLREYRVADFGELAGAVADSGVAVLDVRQRNEYEDSHISHAINIPLHELLARRDEVPAGEVWVHCGSGYRAAIAASLIERPDRTIVLVDDEFANAPEAELVG

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Crispr_ID: NC_018027_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018027_3

2279211-2279309

Orphan

Consensus_repeat	Method
CAATGCGCCTGACGTCCCGGGTGTGCCTGACACCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_018027_3

>merge|NC_018027|3|2279211-2279309|CRISPRCasFinder
CAATGCGCCTGACGTCCCGGGTGTGCCTGACACCCCGGAACCTGGCGACACTCCGGATCAGGCCAATGCACCTGACGTCCCGGGTGTGCCTGACACCCC

>NC_018027|3|3|2279211-2279309|CRISPRCasFinder
CAATGCGCCTGACGTCCCGGGTGTGCCTGACACCCC	GGAACCTGGCGACACTCCGGATCAGGC
CAATGCACCTGACGTCCCGGGTGTGCCTGACACCCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018027.1\|WP_014815482.1\|2273838_2274108_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225993
NC_018027.1\|WP_014815479.1\|2271153_2271471_-\|hypothetical-protein	unknown	unknown	unknown
NC_018027.1\|WP_014815484.1\|2275808_2276576_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_018027.1\|WP_158021458.1\|2274157_2275660_-\|multicopper-oxidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|225043
NC_018027.1\|WP_014815495.1\|2288882_2289116_-\|hypothetical-protein	unknown	unknown	unknown
NC_018027.1\|WP_014815494.1\|2288065_2288857_+\|DUF4239-domain-containing-protein	unknown	unknown	gnl\|CDD\|372881
NC_018027.1\|WP_014815481.1\|2272864_2273482_+\|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	unknown	unknown	gnl\|CDD\|274422
NC_018027.1\|WP_041782876.1\|2279524_2280214_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_018027.1\|WP_014815485.1\|2276572_2277727_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_018027.1\|WP_014815476.1\|2270267_2270450_-\|hypothetical-protein	unknown	unknown	unknown
NC_018027.1\|WP_014815477.1\|2270580_2270766_-\|hypothetical-protein	unknown	unknown	unknown
NC_018027.1\|WP_014815493.1\|2287434_2287905_-\|hypothetical-protein	unknown	unknown	unknown
NC_018027.1\|WP_014815480.1\|2271910_2272336_-\|hypothetical-protein	unknown	unknown	unknown
NC_018027.1\|WP_014815491.1\|2284281_2285523_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227049
NC_018027.1\|WP_014815490.1\|2283362_2284010_+\|MspA-family-porin	unknown	unknown	gnl\|CDD\|370360
NC_018027.1\|WP_014815487.1\|2280174_2281632_-\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|223715
NC_018027.1\|WP_041781852.1\|2270855_2271038_-\|hypothetical-protein	unknown	unknown	unknown
NC_018027.1\|WP_014815492.1\|2286109_2287273_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373735
NC_018027.1\|WP_014815489.1\|2282595_2283243_+\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NC_018027.1\|WP_014815488.1\|2281662_2282391_-\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239486

Protein	Function_ID	Function_description	E-value
NC_018027.1\|WP_014815482.1\|2273838_2274108_-\|hypothetical-protein	gnl\|CDD\|225993	COG3462, COG3462, Predicted membrane protein [Function unknown].	1.05604e-05
NC_018027.1\|WP_014815489.1\|2282595_2283243_+\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	5.93021e-42
NC_018027.1\|WP_014815484.1\|2275808_2276576_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.23837e-86
NC_018027.1\|WP_158021458.1\|2274157_2275660_-\|multicopper-oxidase-domain-containing-protein	gnl\|CDD\|225043	COG2132, SufI, Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism].	4.21129e-94
NC_018027.1\|WP_014815494.1\|2288065_2288857_+\|DUF4239-domain-containing-protein	gnl\|CDD\|372881	pfam14023, DUF4239, Protein of unknown function (DUF4239). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 254 and 270 amino acids in length.	8.59142e-12
NC_018027.1\|WP_014815481.1\|2272864_2273482_+\|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	gnl\|CDD\|274422	TIGR03083, TIGR03083, uncharacterized Actinobacterial protein TIGR03083. This protein family pulls together several groups of proteins, each very different from the others. They share in common three conserved regions. The first is a region of about 38 amino acids, nearly always at the N-terminus of a protein. This region has a bulky hydrophobic residue, usually Trp, at position 29, and a His residue at position 37 that is invariant, so far, in over 150 instances. The second conserved region has a motif [DE]xxxHxxD. The third conserved region contains a hydrophobic patch and a well-conserved Arg residue. Most examples are found in the Actinobacteria, including the genera Mycobacterium, Corynebacterium, Streptomyces, Nocardia, Frankia, etc. The pattern of near-invariant residues against a backdrop of extreme sequence divergence suggests enzymatic activity and conservation of active site residues.	2.43379e-19
NC_018027.1\|WP_014815491.1\|2284281_2285523_-\|hypothetical-protein	gnl\|CDD\|227049	COG4705, COG4705, Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown].	1.25413e-75
NC_018027.1\|WP_014815485.1\|2276572_2277727_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.00478e-58
NC_018027.1\|WP_041782876.1\|2279524_2280214_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.11158e-79
NC_018027.1\|WP_014815487.1\|2280174_2281632_-\|HAMP-domain-containing-protein	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.3114e-42
NC_018027.1\|WP_014815490.1\|2283362_2284010_+\|MspA-family-porin	gnl\|CDD\|370360	pfam09203, MspA, MspA. MspA is a membrane porin produced by Mycobacteria, allowing hydrophilic nutrients to enter the bacterium. The protein forms a tightly interconnected octamer with eightfold rotation symmetry that resembles a goblet and contains a central channel. Each subunit fold contains a beta-sandwich of Ig-like topology and a beta-ribbon arm that forms an oligomeric transmembrane barrel.	2.0538e-38
NC_018027.1\|WP_014815492.1\|2286109_2287273_-\|hypothetical-protein	gnl\|CDD\|373735	pfam15308, CEP170_C, CEP170 C-terminus. This family includes the C-terminus of centrosomal protein of 170 kDa (CEP170).	0.00137278
NC_018027.1\|WP_014815488.1\|2281662_2282391_-\|phosphatase-PAP2-family-protein	gnl\|CDD\|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	1.05912e-31

>NC_018027.1|WP_014815485.1|2276572_2277727_+|HAMP-domain-containing-histidine-kinase
MRARTGLGMRRRLLLAQTLVLLAGGVTTWIVAAVVGPPLFREHLHQAGVPHNSSEQFHAEQAYQHATAISIAVAITVAALTAFVVAAYFSRRLQRSVIEVSTAATAVAEGHYDIRVAPPQLGDEFDELACAFNQMAERLQAVESTRRRLFGDLAHEIRTPVSVLEAYLEAVEDGVKTLDPQTISMLREQTGRLVRFSADAAALAQAEEAHTTITPEWVDSRQLADAVTAAVADRYAAKGVAVTTRVADGPRLWADRQRLAQVLGNLLDNALRHTPPGGHVTLGVALVGTDAVFTVADDGEGVAAEHLPHLFERFYRADSARDRDHGGAGIGLAIAKALTEAHGGRISAASRGPGTGTTFTVTVPTRQPAGNSGEPRQTASTVGP
>NC_018027.1|WP_014815484.1|2275808_2276576_+|response-regulator-transcription-factor
MGAMDSAPRPSVGTANSGYRALVVDDEAPLAEVVASYLEREQFDVTVRHSGADALAVARDVDPDVVVLDLGLPGIDGVEVCRQLRTFSDAYVVMLTARDSEVDKIVGLSVGADDYVTKPFSPRELVARIRAMLRRPRTVGAPVPVRNARDASAPAPRVFGSLTIDVAGRAVHLDGEPINLTRTEFDILAALSSRPGVVWSRRQLIDAIWGEPWVGNDHLVDVHVGHVRRKLGDDPSNPRFVFTVRGVGYRMGTGQ
>NC_018027.1|WP_158021458.1|2274157_2275660_-|multicopper-oxidase-domain-containing-protein
MTRRGFLAASALGGAALVACGRSDTSAKPAAAGVADRISAVDAARPHTGKSVTAQLTPGPADIDLGGVHARTFAYNGQVPGPLIRANVGDEITVSVTAGLDHATSVHWHGIALRNDMDGAAPATPDISPGASFTYRFTSPYPGTYWAHPHTGLDTDYGLYLPVIIDDPADPGRYDAEWIVMLDDWTSGVGPSPDQIFEQLRSMSAPGGAPMPGMGGMGPAPGTRGPNGSRPSELLGSDGGDVTYPYYLVNGRIPTAATTFTAKPGQRIRLRLINAGADTAFRVALAGHRMTVTHTDGFPIQPTDVDALLLGMGERYDVTVIAGDGVFPLVAAAEGKNAVARALLSTAAGSSPDPSFRPPELTRQIGTVETFIAPTQFNLPPSSDVALQARLTGTMARYDWMINGHPYDHTVPLTIREGQRATLTFTNASMMWHPMHLHGHTFQVIKADGSPGPRKDTVIVKPMQTITVRLVADNPGIWMLHCHNGYHMDAGMMTTLDYTG
>NC_018027.1|WP_014815482.1|2273838_2274108_-|hypothetical-protein
MMFWTDHNMSGWGYAGMGIGMVLFWLLVLAGIVALFRYGTGTTRSRDIPPPQPYADSPEQLLAIRFAQGEIDDQEYQMRLAVLRDAMRR
>NC_018027.1|WP_014815481.1|2272864_2273482_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme
MDGLEMATAERTDLADLLETLTPGQWEAPSLCQGWRVRDVVAHVMSFDGVSLLGMFRRAIRGRILHINQVGVDELASLTTEQLLHRLRAHLRPQGLATTFGGRLALLDVTIHHQDIRRPLGMPRQIPAERLRCVLGASLCSPELPAWRLARGIRLAPTDLDWSHGSGPELTGPAEAVLMAITGRRSAIGELAGPGQPVLAGRLGR
>NC_018027.1|WP_014815480.1|2271910_2272336_-|hypothetical-protein
MTHRGSRLSAPVAVLCVAAVLHPAAAVADIVGFTSPSRNVGCMLDDDYVRCDIAERQWSPPPRPAGCPAVTGYGQGIELQATGPASFVCAGDTAMGGGPALPYGQVQARAGISCGSEPSGMRCSNSEGHGFTLSRQGYTLL
>NC_018027.1|WP_014815479.1|2271153_2271471_-|hypothetical-protein
MSATSIPDSVALPPGAYTQDTWQAAEPQPYRIILGGDRTIAGHRAVVSPSAVQWADGSVDDGRTEAPHVYAFNLEESNPLTTDQARELAAALLAAADEVDGWVAR
>NC_018027.1|WP_041781852.1|2270855_2271038_-|hypothetical-protein
MSGHPATVTLFGTQLHDGTVEDRCIRVGGVHEDDELDSETARRLGQALLDAADDLDRLQP
>NC_018027.1|WP_014815477.1|2270580_2270766_-|hypothetical-protein
MSSKPQAGPNGYQEPRPDHLPLSAAVWDASHNFGRSSQTVVQKLYDAVKQLEADVIAMRGE
>NC_018027.1|WP_014815476.1|2270267_2270450_-|hypothetical-protein
MPVTIEHASADELHERLRSVLAAVGMEYDELADLASRYMLTPEELAAWDEVRAIRFLLGG
>NC_018027.1|WP_041782876.1|2279524_2280214_+|response-regulator-transcription-factor
MKVLMVEDEPRFASSIVMGLRAEGFVVVHVDNGVDGLWEATEHQFDVVILDIMLPRLNGYEVLRRMRAREVWTPVLMLTAKDGDYDQTDAFDLGADDYLSKPVAFIVLLARLRALLRRGAPQRPVVLSAGTLTLDPARRVVERDGAPIELTPREYGVLEYLMRRKDVVVTKQEMLQHVWDAHYSGPDNVVEVYVGYVRRKIDTPFGTNTIQTVRGAGYRLDSGEYRSGS
>NC_018027.1|WP_014815487.1|2280174_2281632_-|HAMP-domain-containing-protein
MLGRFAARSVRGRVSARPSPRVRKPWSWWRPRYWGISARSAFVSASVVLVALIVAGAGLAFILYRSLLSGVDDAASGRVRDIVAALRYDTAAELDAPLVATDQRIVAVQVIDGSGTVVQRSQSAPDAPMVPPASIGTDLRVGLPDGAALDGDARISGLAVTGRTGHYTVLVGAGSEAVESTVRTVIVLLAGAAPIVMAVAAAATYLLVHRSLRSVDAIRSRVSDISATDLHERIPVPSNHNEISALAVTMNEMLARIEAGHEAQRRFVGDASHELRSPVAAILSALDVASAHPELLDEKMAELTLRPEAHRMQSLVEDLLLLARADERGLMLRRREVDLDDLASAEVGRILRETSVPIDAELVPTRLIGDASGLSRVLRNLLDNAVRHAFSSVELRVWPTSTHAVVMVGNDGTAIPEQDRERVFARFVRLDSDRSRRGGGTGLGLAIVAEVVGAHGGTAVITERSGGGTLVTVQLPLRYSPESSR
>NC_018027.1|WP_014815488.1|2281662_2282391_-|phosphatase-PAP2-family-protein
MDELLPNVRQPRRTGGRLRLRLWLIVTLVVVFAVLGVSAYRVGSGGAWDHDVLHWLIEQRRGWLTATAIALTEAGSPIAMGLLAVIAAALLWWRRRAPLQGIVVLSTLVVASGISTVTKVIVGAHRPPRVVQLVREVDPSFPSGHVTGTLALLGVLAVVIGRDRRAAVRVALAAGVAASTVMVAATRLYLGVHWLTDVCGGAMLGAAAVVGSSLMLDKVAGSRDGTADRPDESAAVKASPMA
>NC_018027.1|WP_014815489.1|2282595_2283243_+|DedA-family-protein
MQQLIVTYGLIAIFVLMAAESACIPVPSEVTMLLGGALAAGAVSGVHPNVLAVIGVGTAGNVAGSYLAWLVGRYGGRPVLHRWARFVLLRPSEVDRAQDWFARRGSLSVLWARLLPGIRTFISLPAGIAAMPPIRFGVYTLAGCLPWTAALTVAGYTIGANWHVLEQALRGPSYVITAIAVMSVVAAAVVAVRRRRRKDADEAESGRRFVEISTD
>NC_018027.1|WP_014815490.1|2283362_2284010_+|MspA-family-porin
MKLPVRLLAALTVGVGVLFAGSGTSHAALDNQLSLVDGQGRTLTIQQWNTFLNGVSPLDRNRLTREWFHSGKAVYSVTGKGADDFTGTLELGYQIGFPWSLGVGINFSYTTPNVALDKQDVIGTRNGLIDLFPPISTPPLLPGVSFSADLGNGPGVQEVATFSVDVKGPKGAVAVSNAHGTVTGAAGGVLLRPYARLISSTGDSVTTYGEPWNMN
>NC_018027.1|WP_014815491.1|2284281_2285523_-|hypothetical-protein
MSETTRLTVNTPPRVALSKVPEITIWFWVIKILCTTVGESFADWINMTLGVGLVPTAVIFTFVLCVVLGCQMALNRYQPFAYWLTVVVLSVTGTLYTDILTDALGVPLAVSTAVFAVALAAVFGVWYARERTLSIHSIVTLPRESFYWVAILVTFALGTAVGDWTLELTGWGPGLSVLLPAGLIVAIAIGWRLGANAVLSFWLAYILTRPLGANLGDWLGLPKDEQGLGLGVAVTSVIFLVAILATVVYLSVTHADVIGAPDEPRAVRPGREKVMLGYFAVLAVATAALLTFAHAQPHATPSAESESGPTAIAPITAGQATAHFPAAEITNFRAITTQMLTQIQGGDQAGATTSAKNLETAWDADQSKLQAMDGATWTAIDGRIDAVLTAVRATDPDPAVETKTLSDLLSALQ
>NC_018027.1|WP_014815492.1|2286109_2287273_-|hypothetical-protein
MKTIDMISASAAITVCGKNLATVGIALATASAIAIAPTIEPPPRPVPAVHLTVASSPIAVTPQAQESNVLGALLHLNLSEFIVPPSAGQPVPSRPTAPTPVSTGFEFEDAIINTYHAIEPWVRYGFEVATYAVGWIPYVGWLSPQIMIFYNFGERIVESLVVNSANWLWGPLPFGEGLANVARDSWNALVQLGIDEWNFWLPPLPPLPFTTRQTQAQLTSAEVAAAADQPMAGAAGRPHPWRDVLGAALGRLLPGSHSLAPQNANLQRGIDRPVLVDLAAANAAANPRTRLHMPRDRNGADTAPSDSSATAADPGAADHLVSGVGSREAGPLGYQDNSKQLVKPSRTAKNSGPSPRLSKNSFTSAGKRNAGTADPSNSRSDGTHKHR
>NC_018027.1|WP_014815493.1|2287434_2287905_-|hypothetical-protein
MDFPSWSLGLSLIVLTIAMHTTAVVFMALGLETRFRVQIDTHARDRLHAIPAVIVRIGAVALLLAALHGVEGVTWAVAYRWLGAFDSFTDASVYSLATMTTSETRGITLPARWQMLSALEAVNGGLLFGISTAFLFAVIQVHWQMLLHRSDRSADH
>NC_018027.1|WP_014815494.1|2288065_2288857_+|DUF4239-domain-containing-protein
MGDYGLAGLWMLLAGSLVVAVLIATGSILLADRTLPKSVGQGHNAALSPFLTCVSLVYGALLGFTIVVAWEQFSSAETNVSNEASTIVTMYRQTVGMPVDEQTQMRALLRKYAGAVEGPEWQNSIRAGTGTESARDALNEMYTVLGNEKSSVATSPITQKFLDQLTTLASQRNQRILDAKPRIPGLLWTGLLFGGVVLLGIGGFMRLGSARAHLILLSAIAVLLGLLLFVVFWLDHPFGNELGVTSAPFEQSLNVFDSIDRGA
>NC_018027.1|WP_014815495.1|2288882_2289116_-|hypothetical-protein
MQSRSAWICATASVVAVLSTAAGTPHASAEPLATCSSEVVDGVEVDYCVGNPDVATAGEVPGVNVDFEFTLGFGLGR

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Crispr_ID: NC_018027_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018027_4

2336705-2337370

Orphan

Consensus_repeat	Method
CGACGCCGCCNGCGCCGGGTGCNCCGGGTGNNCCGGTGG	CRT

11 spacers

The CRISPR arrays of NC_018027_4

>merge|NC_018027|4|2336705-2337370|CRT
CGACGCCGCCCGCGCCGGGTGTTCCGGGTGTGCCGGTGCAGGGGTCGTCGAGTGTGGTGACTCCTCCGGCGCCGGGTGTGCCTGGGACACCGGTGAATTCGTCGGTGGAGGTAGCGACGCCGCCGGCTCCGGGTGCGCCGGGTGTGCCGGTGGTGACTGAGGCGGGTGCGGCGACGCCGCCTGCGCCGGGCGCCCCGGGTGTGCCGGTGGTGACTGAGGCGGGTGCGGCGACGCCGCCTGCGCCGGGTGCGCCGGGTGTGCCGGTGGTGACTGAGGCGGGTGCGGCGACGCCGCCTGCGCCGGGTGCGCCGGGTGTGCCGGTGGTGACTGAGGCGGGTGCGGCGACGCCGCCTGCGCCGGGTGCGCCGGGTGTGCCGGTGGTGACTGAGGCGGGTGCGGCGACGCCGCCTGCGCCGGGCGCCCCGGGTGTGCCGGTGGTGACTGAAGGGGCTGCGGCGACGCCGCCTGCGCCGGGTGCCCCGGGTGCTCCGGTGGCGGTGCCCGCGGGTGCGGCGACGCCGCCTGCGCCGGGTGCCCCGGGTGCTCCGGTGGTGACTGAAGGGGCTGTGGCGACGCCGCCTGCGCCGGGTGCGCCGGGTGCTCCGGTGGCGGTGCCCGCGGGTGCGGCGACGCCGCCCGCTCCGGGCGCCCCCGCGGCGCCGATCT

>NC_018027|4|1|2336705-2337370|CRT
CGACGCCGCCCGCGCCGGGTGTTCCGGGTGTGCCGGTGC	AGGGGTCGTCGAGTGTGG
TGACTCCTCCGGCGCCGGGTGTGCCTGGGACACCGGTGA	ATTCGTCGGTGGAGGTAG
CGACGCCGCCGGCTCCGGGTGCGCCGGGTGTGCCGGTGG	TGACTGAGGCGGGTGCGG
CGACGCCGCCTGCGCCGGGCGCCCCGGGTGTGCCGGTGG	TGACTGAGGCGGGTGCGG
CGACGCCGCCTGCGCCGGGTGCGCCGGGTGTGCCGGTGG	TGACTGAGGCGGGTGCGG
CGACGCCGCCTGCGCCGGGTGCGCCGGGTGTGCCGGTGG	TGACTGAGGCGGGTGCGG
CGACGCCGCCTGCGCCGGGTGCGCCGGGTGTGCCGGTGG	TGACTGAGGCGGGTGCGG
CGACGCCGCCTGCGCCGGGCGCCCCGGGTGTGCCGGTGG	TGACTGAAGGGGCTGCGG
CGACGCCGCCTGCGCCGGGTGCCCCGGGTGCTCCGGTGG	CGGTGCCCGCGGGTGCGG
CGACGCCGCCTGCGCCGGGTGCCCCGGGTGCTCCGGTGG	TGACTGAAGGGGCTGTGG
CGACGCCGCCTGCGCCGGGTGCGCCGGGTGCTCCGGTGG	CGGTGCCCGCGGGTGCGG
CGACGCCGCCCGCTCCGGGCGCCCCCGCGGCGCCGATCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_018027.1\|WP_014815539.1\|2341792_2342230_+\|TIGR02611-family-protein	unknown	unknown	gnl\|CDD\|131660
NC_018027.1\|WP_014815528.1\|2327489_2329145_+\|glycoside-hydrolase-family-13-protein	unknown	unknown	gnl\|CDD\|200471
NC_018027.1\|WP_014815544.1\|2346565_2347696_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340831
NC_018027.1\|WP_014815530.1\|2330241_2330892_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NC_018027.1\|WP_014815527.1\|2325903_2327214_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270453
NC_018027.1\|WP_014815526.1\|2324974_2325907_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NC_018027.1\|WP_014815540.1\|2342319_2344395_+\|threonine--tRNA-ligase	unknown	unknown	gnl\|CDD\|237050
NC_018027.1\|WP_158021345.1\|2335273_2335966_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367272
NC_018027.1\|WP_014815538.1\|2341166_2341796_+\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|239527
NC_018027.1\|WP_014815537.1\|2340272_2341145_+\|oxidoreductase	unknown	unknown	gnl\|CDD\|381314
NC_018027.1\|WP_014815543.1\|2345609_2346566_+\|phosphatidylinositol-mannoside-acyltransferase	unknown	unknown	gnl\|CDD\|236131
NC_018027.1\|WP_014815529.1\|2329241_2330225_+\|NAD(P)H-nitroreductase	unknown	unknown	gnl\|CDD\|236122
NC_018027.1\|WP_014815541.1\|2344396_2344945_+\|HIT-domain-containing-protein	unknown	unknown	gnl\|CDD\|238606
NC_018027.1\|WP_041782900.1\|2339736_2340234_-\|DUF1990-domain-containing-protein	unknown	unknown	gnl\|CDD\|378157
NC_018027.1\|WP_014815532.1\|2331743_2332739_-\|NAD(P)H-nitroreductase	unknown	unknown	gnl\|CDD\|236122
NC_018027.1\|WP_014815531.1\|2330925_2331750_-\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NC_018027.1\|WP_014815542.1\|2344941_2345613_+\|CDP-alcohol-phosphatidyltransferase-family-protein	unknown	unknown	gnl\|CDD\|223632
NC_018027.1\|WP_081495141.1\|2338895_2339597_-\|GAF-and-ANTAR-domain-containing-protein	unknown	unknown	gnl\|CDD\|377145
NC_018027.1\|WP_158021344.1\|2334773_2335226_-\|hypothetical-protein	unknown	unknown	unknown
NC_018027.1\|WP_158021461.1\|2332909_2334565_+\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|226951

Protein	Function_ID	Function_description	E-value
NC_018027.1\|WP_014815539.1\|2341792_2342230_+\|TIGR02611-family-protein	gnl\|CDD\|131660	TIGR02611, Putative_membrane_protein, TIGR02611 family protein. Members of this family are Actinobacterial putative proteins of about 150 amino acids in length with three apparent transmembrane helix and an unusual motif with consensus sequence PGPGW. [Hypothetical proteins, Conserved].	3.64156e-26
NC_018027.1\|WP_014815528.1\|2327489_2329145_+\|glycoside-hydrolase-family-13-protein	gnl\|CDD\|200471	cd11332, AmyAc_OligoGlu_TS, Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), trehalose synthase (also called maltose alpha-D-glucosyltransferase), and related proteins. Oligo-1,6-glucosidase (EC 3.2.1.10) hydrolyzes the alpha-1,6-glucosidic linkage of isomaltooligosaccharides, pannose, and dextran. Unlike alpha-1,4-glucosidases (EC 3.2.1.20), it fails to hydrolyze the alpha-1,4-glucosidic bonds of maltosaccharides. Trehalose synthase (EC 5.4.99.16) catalyzes the isomerization of maltose to produce trehalulose. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NC_018027.1\|WP_014815544.1\|2346565_2347696_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	2.63092e-68
NC_018027.1\|WP_014815530.1\|2330241_2330892_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.40628e-65
NC_018027.1\|WP_014815527.1\|2325903_2327214_-\|extracellular-solute-binding-protein	gnl\|CDD\|270453	cd14750, PBP2_TMBP, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose; possesses type 2 periplasmic binding fold. This group represents the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.1849e-77
NC_018027.1\|WP_014815526.1\|2324974_2325907_-\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	5.15869e-79
NC_018027.1\|WP_014815540.1\|2342319_2344395_+\|threonine--tRNA-ligase	gnl\|CDD\|237050	PRK12305, thrS, threonyl-tRNA synthetase; Reviewed.	0
NC_018027.1\|WP_158021345.1\|2335273_2335966_+\|hypothetical-protein	gnl\|CDD\|367272	pfam02956, TT_ORF1, TT viral orf 1. TT virus (TTV), isolated initially from a Japanese patient with hepatitis of unknown aetiology, has since been found to infect both healthy and diseased individuals and numerous prevalence studies have raised questions about its role in unexplained hepatitis. ORF1 is a large 750 residue protein. The N-terminal half of this protein corresponds to the capsid protein.	0.00343714
NC_018027.1\|WP_014815531.1\|2330925_2331750_-\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	1.46942e-18
NC_018027.1\|WP_014815537.1\|2340272_2341145_+\|oxidoreductase	gnl\|CDD\|381314	cd19088, AKR_AKR13B1, AKR13B family of aldo-keto reductase (AKR). Xylella fastidiosa phenylacetaldehyde dehydrogenase is a founding member of aldo-keto reductase family 13 member B1 (AKR13B1). phenylacetaldehyde dehydrogenase (EC 1.2.1.39) catalyzes the NAD+-dependent oxidation of phenylactealdehyde to phenylacetic acid.	1.55938e-149
NC_018027.1\|WP_014815543.1\|2345609_2346566_+\|phosphatidylinositol-mannoside-acyltransferase	gnl\|CDD\|236131	PRK07920, PRK07920, lipid A biosynthesis lauroyl acyltransferase; Provisional.	2.07372e-172
NC_018027.1\|WP_014815529.1\|2329241_2330225_+\|NAD(P)H-nitroreductase	gnl\|CDD\|236122	PRK07877, PRK07877, Rv1355c family protein.	4.72573e-22
NC_018027.1\|WP_014815541.1\|2344396_2344945_+\|HIT-domain-containing-protein	gnl\|CDD\|238606	cd01275, FHIT, FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into three branches: the Hint branch, which consists of adenosine 5' -monophosphoramide hydrolases, the Fhit branch, that consists of diadenosine polyphosphate hydrolases, and the GalT branch consisting of specific nucloside monophosphate transferases. Fhit plays a very important role in the development of tumours. Infact, Fhit deletions are among the earliest and most frequent genetic alterations in the development of tumours.	1.16875e-60
NC_018027.1\|WP_014815538.1\|2341166_2341796_+\|PaaI-family-thioesterase	gnl\|CDD\|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	1.60266e-09
NC_018027.1\|WP_014815532.1\|2331743_2332739_-\|NAD(P)H-nitroreductase	gnl\|CDD\|236122	PRK07877, PRK07877, Rv1355c family protein.	5.58657e-20
NC_018027.1\|WP_041782900.1\|2339736_2340234_-\|DUF1990-domain-containing-protein	gnl\|CDD\|378157	pfam09348, DUF1990, Domain of unknown function (DUF1990). This family of proteins are functionally uncharacterized.	8.34456e-63
NC_018027.1\|WP_014815542.1\|2344941_2345613_+\|CDP-alcohol-phosphatidyltransferase-family-protein	gnl\|CDD\|223632	COG0558, PgsA, Phosphatidylglycerophosphate synthase [Lipid metabolism].	3.21358e-27
NC_018027.1\|WP_081495141.1\|2338895_2339597_-\|GAF-and-ANTAR-domain-containing-protein	gnl\|CDD\|377145	pfam03861, ANTAR, ANTAR domain. ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins. The majority of the domain consists of a coiled-coil.	2.32698e-16
NC_018027.1\|WP_158021461.1\|2332909_2334565_+\|GAF-domain-containing-protein	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.44892e-45

>NC_018027.1|WP_158021345.1|2335273_2335966_+|hypothetical-protein
MAVPRRRLPPREFLSARRWPTWRPRRRLRRACRSSAMPARRFRRCRPLRAAPSRFLSGRARPRPRPLQAAPSRFLSVQVRRRPRLPPAHRSSVRPALRHPRSPVFRALRWRQRRAMPDPAEQAFPVPRSRVPQAQPRPAVRLALALPVPEGPVLSVRAVLLALVLQSSVKPVRWVRVVLLALALLSSVKLARLRRRHPERLVLRSPRPPGTRPRPLRLPRALRWPVRVVS
>NC_018027.1|WP_158021344.1|2334773_2335226_-|hypothetical-protein
MPPPNDAPRGAGGRGGAGGVAAPTVFDAGLPGPPGTGGVTPDDDVDTEAGGRGGSGGAPAEDELAGGTTTGGGGCPGPPVRDDEALCSAVGMSAGWETICCRIPTHGTPPRVGSAVASGLSNGALRNIPALPIMTTTMPFLVRDMCSQSF
>NC_018027.1|WP_158021461.1|2332909_2334565_+|GAF-domain-containing-protein
MSQLRLRELLTEVQDRVEQIIKGRDRLDGLVEAMLVVTSGLELDETLRTIVHTAIELVDAQYGALGVRGDDDELTAFIYEGIDEPTRELIGHLPEGRGVLGVLMENPKPIRLEDISSHPSSVGFPANHPPMRTFLGVPVRIRDEIFGNLYLTDKLGGQPFSEDDEVLVQALAAAAGIAIDNARLYQLSQARQSWIAATRDIGTELLSGTDPARVFRLLADTAQKLSGAASALVAVPGDPDKPAGEVTELVVVASAGAAAGTELRPIPVGGTAVGEAFVRRTPGRHSGAEIGVGQVTGPSLVLPLRTTTTVAGVLIALRPVGGQAFSADELAMMAAFADQAALAWQLATAQHRMRELDVLTDRDRIARDLHDHVIQRLFAVGLSLQGTIARASSDVVQQRLSDSVDDLQEVIQEIRTAIFDLHGGNSEITRLRQRLDEAVAAFAGAGVRTSVQYVGPLSVITPVLADHAEAVVREAVSNVVRHAEATALSVLVTVGDDLTVEVVDNGRGIGPDVTGSGLINLRRRADDVGGSFAVDAPAGGGTRLVWRAPLP
>NC_018027.1|WP_014815532.1|2331743_2332739_-|NAD(P)H-nitroreductase
MPTTQVGLGVIINALQLACRAPSVLNSQPWRWIVTDDSVDLFADPARLVRSTDRTGRQALISCGAALHHLRVAMSAAGWDSTVSRFPDPDEPLHLARLTFSSAASVSEQQKRRADAILLRRTDRLPFAAPPDWDAFLDVVDAGAQPRGVRLSVLADEMRTELAEASQLTEALRHHDAAYHHEILLWTANFVTSDGIPHSALVSAAESGRVDVASAFPLATHPERRTEMADDHSMIVVLSTDDDSGESILRCGEALSALLLDATVAGLTTCTLTHVTEDPSGREVVASLIANDAIPQVLVRIGRAPALDATPPPTPRRPIEQVVEIRRSATC
>NC_018027.1|WP_014815531.1|2330925_2331750_-|universal-stress-protein
MLGANPAPSVVVGVDGSPAAVDAALWAIDEAIDRDIPLRLVYVIDSTGHDVVDPQDQARRMATADIAVRYVLTAVESTERPVKIEVEILQGRPVEALLEAARSATMLCVGARGLKHATRGRIGSTAAALAAAAQCPVAVVRAHKPHSAVSRAIVVEVSDNQAESAVLRLGLEEARRRGAPVRVLTPARIPSDALSRWERRLAEWRRHFPDVEVTSVKLHGDTLDYLAAHAPAIQLVVTDRGRCGSVGKLIGAPGNAALRDTDCSILVCDPHNAL
>NC_018027.1|WP_014815530.1|2330241_2330892_-|response-regulator-transcription-factor
MVKVFLVDDHEVVRRGLIDLLSSDPELDVVGEAGSVAEAMARIPALQPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLMLTSFTSDEAMLDAILAGASGYVVKDIKGMELAGAIKEVGSGRSLLDNRAAAALMAKLRGEGERTDPLSDLTDQERVLLDLLGEGLTNKQIAARMFLAEKTVKNYVSRLLAKLGMERRTQAAVFVSKLERQHRQGHE
>NC_018027.1|WP_014815529.1|2329241_2330225_+|NAD(P)H-nitroreductase
MGANFPDTETLRSALALANRAPSVHNTQPWYWRVGGHSLHLYANPDLLLPHTDPDRRDLILSCGAVLNHCVVALAALGWQSKIHRCPNPADADHLASLQLHRYPAGELDVTLAAAIPRRRTDRRHYSSWPVPRGDIALMGARAARAGVLLRRVDDLAHLKRLVTEAALAHGTDQEYLAELAAWSGRYASAAGVPARSVPGSNGTSRIPARAFAGGVLTQTEAAEDNAVVIALGTVDDDRLAWLRAGEATSLVLLTATALGLASCPITEPLEIAGTREALREDVFGDDGYPQMLLRVGWAPINADPLPATPRRPLADVVAHLDGSPLD
>NC_018027.1|WP_014815528.1|2327489_2329145_+|glycoside-hydrolase-family-13-protein
MAAEVPSWWQTAVVYQVYIRSFADGNGDGIGDIAGMRDRLPYLAGLGIDAIWINPWYPSPMADAGYDVADYRDIEPAYGTLDEAQALVAEAHAAGIRVLLDIVPNHTSDQHAWFRAALAGEPGARQRYHFRPGRGEDGVQPPNNWQSVFGGPAWTRVADGSWYLHLFAPGQPDLNWDNGEVRAEFEDILAFWFDRGVDGFRIDVAHGMVKEPGLPDTRDAAEAVQSLVQSRAGHPAWDQDGVHEIYRGWRSVANRYRPERIFIAEAWVSSNERLARYLRPDELHTAFQFDFLRAPWRAQVLRAVVDDAIAAAATVGAPPTWVLSNHDVTRTVTRFARSQPEHLIETDWERGRWAGEDPDHVLGRRRARAAALVQLALPGTAYVYQGEELALEEIEDLPDAARQDPTWAQSGFTDVGRDGCRIPLPWNETEPSYGFATESGAATWLPQPAHWAQHSVQAQDRDPDSTLNLYRAALRLRRSLWRDAGDVKWLAVGADVAAFERGGSQCWVNTGDSDVPLPEVMSIALASAPGVRGVLPPDTAVWLRADEAPSM
>NC_018027.1|WP_014815527.1|2325903_2327214_-|extracellular-solute-binding-protein
MKRNQFARGRRRRAIALASAPLIAASLLSGCGSEGGTPTLTWYILPDNGGSAARAKECADASNGAYQVRIESLPSTATAQREQMVRRLAARDSSIDVVSLDVVFTAEFANAGFLRPYTGEEAQRLTAGMLPAPVKTGKWEDKLYGAPYKSNAQLLWYRKSLAAAAGIDPTSPTFTWDEMLKAAVGQKKKIAVQAQRYEGYMVWINALVLSAGGEILKDVQAGRNATPSLATPPGEKAAEIVGNLGRSSAAPTDLSNASEEQARANFQSDQGMFMVNWPYVLAAARTAAEDGTLAQSVVDDIGWARYPRVFPDRPSAPPLGGANLGIGAYTKHPNQAVALVECINALPKATQYMLDEAEPSPYASSYDDPKIRDKYENADLIRESIAEGGPRPLSPFYTDISGAVQQTWHPPASVTAQTPERTDQFMADVLSGRRLL
>NC_018027.1|WP_014815526.1|2324974_2325907_-|sugar-ABC-transporter-permease
MTTVENAPLQTHPGKPPVSERVKGERRLGIYLTLPSYVVMLLVTAYPLVYAVVLSLYNFRLTDPQGRSFVGLRNYLVILTDPVWWNDFVTTLAITVVTVAIELLLGLWFAFVMLRIIRGRGPLRTAILIPYGIVTVVSAFIWRYAFAVDSGFVNQWLNLTDFDWFGNRWSAIFVICLSEIWKTTPFISLLLLAGLVQVPEDMQEAAKVDGATAWQRLWKVTLPNMKAAIMVALLFRTLDAWRIFDNPYVMTAGANNTETISFLAYRQNVTLVNLGMGSAVSVLLFLSVVAIAWVFIKVFRTDLSQVRGDQ
>NC_018027.1|WP_081495141.1|2338895_2339597_-|GAF-and-ANTAR-domain-containing-protein
MEAAHLRVAELVQGLHNRPDTDSDTVIAELAEHAAAEVPGAAHAGITLTRNAKHIETPAATSQWPLLLDKIQQRHREGPCLTAAWEEKTVHVPNLETDERFPNYRRDALAETPIRAVMAFQLFIAGETLGALNVYAEEPHVFGPESRTMGLIFAAHSSVAWNSARREEQFRRALSSRDVIGQAKGMIMERYRVDAVQAFELLRKLSQDSNVPLTQVAVDLVANAQSTDGQVAK
>NC_018027.1|WP_041782900.1|2339736_2340234_-|DUF1990-domain-containing-protein
MKLGHLSGKPLTYSEVGATAGPMPAGYHHLRKSAVIGRGRRRFEEAAERGMRWGMLRGAGVRVEATTDVAEVGAEVLVHLGPVAAPCRVVYVVDEPDRRGFAYGTLPGHAESGEELFLVRYDPATEDVYAEVAAFSRHATWWSRAGSPVTSLAQRLIADRYLRAL
>NC_018027.1|WP_014815537.1|2340272_2341145_+|oxidoreductase
MSTSTGAGASATLTLGNDLTVNRLGFGAMRLTGPGVWGPPADRDECLRVLRRAVELGVDFIDTADSYGPYVSEELIREALHPYDGVVVATKAGLLRTGPDEWPVLGFPAYLRQECEMSLRRLDVETIDLFQLHRIDTKFPLEDQIGELVALQQEGKIRHIGLSEVNADQLDAARAITAIASVQNMYNLTVRTAEPVLDACENHGIAFIPWFPLAAGPLAAPDGPLQRIAAEHHASPSQLALAWLLKRSPVMLPIPGTSKVAHLEENVAAAQIDLTDAEFDTLSQAGAAQA
>NC_018027.1|WP_014815538.1|2341166_2341796_+|PaaI-family-thioesterase
MSADEPTEKAVGGGFNPPTPTTHGGPDYGRFVEAVRTLQDHARAVDAPDHVITEAADLIEKVSQLLDPYDADEWSSPSGRRMDLPNRGNVLGVPMTLHVTEAKRIGGVAQFRRFHLGRNGAAHGGAVAHLFDSLLGFTAAKLSRNRAQRTAFLHVDYRKIAPIEAELQVDAGIDDIVGRKIFVSGRLLDDGQVLAEAHSLFVKLRPGQP
>NC_018027.1|WP_014815539.1|2341792_2342230_+|TIGR02611-family-protein
MTETEHQGRPSFTRRWASWRDRLRERPAANAAYRMVVGVLGVLVLGVGVLAIPYPGPGWAIVFVGLGILATEFDWARRLLAWVRERYDTVMDWFKRQGLWVQVLGAVFTLAIVVATLWLLGALNFAAELFHIEHGWLDSPIGIGS
>NC_018027.1|WP_014815540.1|2342319_2344395_+|threonine--tRNA-ligase
MSAPARPAPAAPIRVAAGTTAGQAVRDAGLPARGEPDAVVVVRDADGRLRDLSWTPAADVEVTPVAADTEDGRSVIRHSAAHVLAQAVQGMFPDAKLGIGPPITDGFYYDFDVAEPFTPEDLEALEKRMRQIVKEGQLFSRRVFESKDQARQELAGEPYKLELIDDKSGDLESSDEVMEIGGDELTAYDNLNPRTREREWGDLCRGPHIPTTRYIPAFKLTRSSAAYWRGDQSNASLQRIYGTAWESQEALDRHLELIEEAQRRDHRKLGVELDLFSFPDELGSGLPVFHPKGGIVRRELEEYSRRKHIEAGYEFVNTPHITKEQLYITSGHLEWYADGMFPPMHIDAEFNEDGSVRKPGQDYYLKPMNCPMHHLIYRSRGRSYRELPLRLFEFGSVYRYEKSGVVHGLTRVRGMTQDDAHIYCTREEMRDELTRLLQFVLELLADYGLDDFYLELSTKDPEKSVGSDEMWEEATETLRDVAESSGLELVPDPGGAAFYGPKISVQVRDALGRSWQMSTIQLDFNMPDRFELEYTAADGSRKRPVLIHRALFGSIERFFGILTEHYAGAFPAWLAPVQVVAIPVADDHIPYLDGLVRELKAHGLRAEVDTSDDRMAKKIVNHTNQRVPFMLLAGDRDVEADAVSFRFGDRTQINGVPREKAVQAIAHWVQRHENAAPTADLVTIDPVANEG
>NC_018027.1|WP_014815541.1|2344396_2344945_+|HIT-domain-containing-protein
MDPEDTIVDRGVGEPDHLQRLWSPHRMTYIVDTVKPGSAASSEPFTDIPTMSDEDGLVVARGQLVYAVLNLYPYNPGHLMVVPYRRVAELENLTGDESAELMAFTQKAIRVMKAVSRPHGFNVGLNLGTSAGGSLSEHLHMHVVPRWGGDANFITIIGGSKVLPQLLRDTRQLLATEWDKQP
>NC_018027.1|WP_014815542.1|2344941_2345613_+|CDP-alcohol-phosphatidyltransferase-family-protein
MSDFYLMTRAAYAKLSRPVARGALRLGLTPDSVTILGTAGSVLGALILFPIGQLWWGAFTVFIFVLADMLDGAMARERGGGTRFGAVLDATCDRISDGAVFCGLLWWAAFGVHSTALVVATMICLVSSQVISYIKARAEASGLSGDGGLIERPERLVIVLVGAGLSGLAFLPMPWLLHVAMWFLAVTSVVTVGQRLHSVRVSPGAMSPLPAAGSSQKPETTEQ
>NC_018027.1|WP_014815543.1|2345609_2346566_+|phosphatidylinositol-mannoside-acyltransferase
MTEQPAGSRTDRGGLSLHPSAWAGHLSDWGYAAGWRLVRAAPEFVARNAFGAGAYYAARGGGPEQLRRNLARVIGTSPEEVPGSLIRASLASYARYWREAFRLPSMDHAALGKQLGVHDIELVWAALEEGRGAVLALPHSGNWDMAGVWLVQNHGTFTTVAERLKPESLYNRFLAYRESLGFEVVPLSGGERPPFDVLRDRLRANGIVCLMADRDLTRTGVQVDFFGEPTRLPGGPARLALATGAALFPVHCWFEPDDWRMQVYPELDVSSGDVTAITQALADRFADNIAAHPEDWHMMQPQWLADLSAERRARLEET
>NC_018027.1|WP_014815544.1|2346565_2347696_+|glycosyltransferase-family-4-protein
MRIGMVCPYSFDVPGGVQSHVLQLAEVMHGNGHEVSVLAPASPDASVSLPDYVVSGGKAVPIPYNGSVARLRFGPATHRRVKKWLQHGDFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTSTTKSLTLSVFEPILRPMHEKIVGRIAVSDLARRWQMEALGSDAVEIPNGVDVASFASAPRLAGYPRPGKSVLFLGRYDEPRKGMAVLLRALPALVERFADIEILVVGRGDEDQLREQAGALAGHLRFLGQVDDAQKASAMRSADVYCAPHTGGESFGIVLVEAMAAGTAVVASGLDAFRRVLNDGEAGRLVAVDDSDALAGGLIDMLTDDAARARYVECATALVQRYDWSVVAAQIMRVYETVAGAGVKVQVAG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_018027_4	4.1\|2336744\|18\|NC_018027\|CRT	2336744-2336761	18	NC_018027.1	2336630-2336647	0	1.0
NC_018027_4	4.9\|2337200\|18\|NC_018027\|CRT	2337200-2337217	18	NC_018027.1	5233180-5233197	1	0.944
NC_018027_4	4.9\|2337200\|18\|NC_018027\|CRT	2337200-2337217	18	NC_018027.1	5496239-5496256	1	0.944
NC_018027_4	4.11\|2337314\|18\|NC_018027\|CRT	2337314-2337331	18	NC_018027.1	5233180-5233197	1	0.944
NC_018027_4	4.11\|2337314\|18\|NC_018027\|CRT	2337314-2337331	18	NC_018027.1	5496239-5496256	1	0.944

1. spacer 4.1|2336744|18|NC_018027|CRT matches to position: 2336630-2336647, mismatch: 0, identity: 1.0

aggggtcgtcgagtgtgg	CRISPR spacer
aggggtcgtcgagtgtgg	Protospacer
******************

2. spacer 4.9|2337200|18|NC_018027|CRT matches to position: 5233180-5233197, mismatch: 1, identity: 0.944

cggtgcccgcgggtgcgg	CRISPR spacer
cggtgccggcgggtgcgg	Protospacer
******* **********

3. spacer 4.9|2337200|18|NC_018027|CRT matches to position: 5496239-5496256, mismatch: 1, identity: 0.944

cggtgcccgcgggtgcgg	CRISPR spacer
cggtgcccgcggctgcgg	Protospacer
************ *****

4. spacer 4.11|2337314|18|NC_018027|CRT matches to position: 5233180-5233197, mismatch: 1, identity: 0.944

cggtgcccgcgggtgcgg	CRISPR spacer
cggtgccggcgggtgcgg	Protospacer
******* **********

5. spacer 4.11|2337314|18|NC_018027|CRT matches to position: 5496239-5496256, mismatch: 1, identity: 0.944

cggtgcccgcgggtgcgg	CRISPR spacer
cggtgcccgcggctgcgg	Protospacer
************ *****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP015007	Aminobacter aminovorans strain KCTC 2477 plasmid pAA02, complete sequence	238648-238678	4	0.871
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP024924	Sphingomonas sp. Cra20 plasmid unnamed, complete sequence	32579-32609	5	0.839
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP029832	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence	286360-286390	5	0.839
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	387287-387317	6	0.806
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	509602-509632	6	0.806
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1957884-1957914	6	0.806
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	315937-315967	6	0.806
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	1745107-1745137	6	0.806
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	58855-58885	6	0.806
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	427271-427301	6	0.806
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP007797	Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence	213072-213102	6	0.806
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	161846-161876	6	0.806
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	418749-418779	6	0.806
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	309448-309478	6	0.806
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MT024869	Arthrobacter phage Lego, complete genome	16534-16564	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP021407	Celeribacter manganoxidans strain DY25 plasmid pDY25-C, complete sequence	33594-33624	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MN586026	Gordonia phage Leonard, complete genome	44275-44305	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NC_031112	Gordonia phage Phinally, complete genome	44272-44302	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1127943-1127973	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1059705-1059735	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1434361-1434391	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP049734	Rhizobium leguminosarum strain A1 plasmid unnamed1, complete sequence	252424-252454	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP053444	Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eB, complete sequence	40715-40745	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	CP049734	Rhizobium leguminosarum strain A1 plasmid pRLa11, complete sequence	41156-41186	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP030762	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed2, complete sequence	282200-282230	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP022670	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR5, complete sequence	119784-119814	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP054035	Rhizobium sp. JKLM13E plasmid pPR13E04, complete sequence	207038-207068	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MK279899	Arthrobacter phage Maja, complete genome	5299-5329	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP050096	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b3, complete sequence	43944-43974	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP050102	Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b2, complete sequence	43948-43978	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP050107	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b1, complete sequence	43925-43955	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_LR134459	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 17, complete sequence	114482-114512	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	CP021131	Meiothermus taiwanensis strain WR-220 plasmid pMtWR-220, complete sequence	175087-175117	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP050112	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b5, complete sequence	43924-43954	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP054024	Rhizobium sp. JKLM12A2 plasmid pPR12A203, complete sequence	283868-283898	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP017944	Phyllobacterium zundukense strain Tri-48 plasmid unnamed4, complete sequence	225962-225992	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP015738	Shinella sp. HZN7 plasmid pShin-02, complete sequence	277839-277869	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NC_009717	Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence	26486-26516	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NC_009717	Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence	28633-28663	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP014797	Salipiger profundus strain JLT2016 plasmid pTPRO1, complete sequence	208496-208526	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MN234234	Arthrobacter phage Lymara, complete genome	38114-38144	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NC_023316	Streptomyces sp. 14R-10 plasmid pZL1, complete sequence	68735-68765	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_LN832562	Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence	83198-83228	7	0.774
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	KX641260	Mycobacterium phage Stasia, complete genome	10234-10264	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	KY083059	Mycobacterium phage Achebe, complete genome	9789-9819	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	KX550442	Mycobacterium phage Badger, complete genome	9790-9820	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MN284905	Mycobacterium phage AbbysRanger, complete genome	9801-9831	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MK359322	Mycobacterium phage Datway, complete genome	9801-9831	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MK875799	Mycobacterium phage Xena, complete genome	9789-9819	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NC_042308	Mycobacterium virus Backyardigan, complete genome	9801-9831	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NC_023709	Mycobacterium phage Wile, complete genome	9802-9832	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1644157-1644187	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1674073-1674103	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	102976-103006	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	111680-111710	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NC_008381	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL10, complete sequence	73471-73501	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP006369	Aureimonas sp. AU20 plasmid pAU20b, complete sequence	263215-263245	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	367023-367053	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP054615	Azospirillum oryzae strain KACC 14407 plasmid unnamed1, complete sequence	268669-268699	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	165918-165948	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP033315	Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence	171765-171795	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP022568	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK04, complete sequence	206600-206630	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MH590593	Mycobacterium phage Rabinovish, complete genome	136974-137004	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MH045567	Microbacterium phage Elva, complete genome	6976-7006	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MN703413	Arthrobacter phage Powerpuff, complete genome	16585-16615	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MT024871	Arthrobacter phage YesChef, complete genome	16585-16615	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP025017	Rhizobium leguminosarum strain Norway plasmid pRLN5, complete sequence	116998-117028	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1021272-1021302	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_LR134456	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 14, complete sequence	34778-34808	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP025613	Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed1, complete sequence	751155-751185	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP011518	Pandoraea oxalativorans strain DSM 23570 plasmid pPO70-1, complete sequence	173500-173530	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP029830	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence	251661-251691	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP034351	Streptomyces sp. W1SF4 plasmid p1, complete sequence	355974-356004	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	159786-159816	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	517783-517813	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NC_016585	Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence	547759-547789	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MH825699	Streptomyces phage Darolandstone, complete genome	28129-28159	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_LR134469	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 27, complete sequence	100153-100183	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP015006	Aminobacter aminovorans strain KCTC 2477 plasmid pAA01, complete sequence	285236-285266	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP015530	Rhodococcus sp. WB1 plasmid pWB1, complete sequence	6451-6481	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP011296	Rhodococcus erythropolis strain BG43 plasmid pRLCBG43, complete sequence	8129-8159	8	0.742
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MK494117	Mycobacterium phage Miramae, complete genome	9749-9779	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MT310879	Mycobacterium phage MA5, complete genome	9013-9043	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MK359310	Mycobacterium phage Katalie136, complete genome	9801-9831	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MK279898	Mycobacterium phage Cici, complete genome	9789-9819	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	KX683423	Mycobacterium phage BabyRay, complete genome	9641-9671	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MK494129	Mycobacterium phage AvatarAhPeg, complete genome	9759-9789	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MF919498	Mycobacterium phage Cindaradix, complete genome	9501-9531	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MK494115	Mycobacterium phage Bumblebee11, complete genome	9801-9831	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	KX579975	Mycobacterium phage Mundrea, complete genome	9754-9784	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MF668278	Mycobacterium phage Morpher26, complete genome	9801-9831	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MG962370	Mycobacterium phage Kykar, complete genome	9451-9481	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	AF271693	Mycobacterium virus Bxb1, complete genome	9936-9966	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MH576975	Mycobacterium phage Target, complete genome	10674-10704	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	JN699000	Mycobacterium virus BillKnuckles, complete genome	10567-10597	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NC_002656	Mycobacterium phage Bxb1, complete genome	9936-9966	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	JN699016	Mycobacterium phage Kugel, complete genome	9954-9984	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	893731-893761	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP012477	Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence	79622-79652	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1381218-1381248	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MG099952	Mycobacterium phage WunderPhul, complete genome	10467-10497	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	KX375815	Mycobacterium phage ToneTone, complete genome	10399-10429	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	KF560333	Mycobacterium phage Artemis2UCLA, complete genome	10369-10399	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MK359360	Mycobacterium phage Hexamo, complete genome	10441-10471	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	KX576638	Mycobacterium phage Gruunaga, complete genome	10460-10490	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NC_042309	Mycobacterium virus Gladiator, complete genome	10460-10490	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MN728683	Mycobacterium phage Yokurt, complete genome	10467-10497	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NC_022965	Mycobacterium phage CloudWang3, complete genome	10464-10494	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MN813697	Mycobacterium phage Noelle, complete genome	9858-9888	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	JN698999	Mycobacterium phage Blue7, complete genome	10460-10490	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MF668288	Mycobacterium phage Wiks, complete genome	10467-10497	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MT310885	Mycobacterium phage AN9, complete genome	10360-10390	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	AP018476	Mycobacterium phage C3 DNA, complete sequence	10360-10390	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NC_042318	Mycobacterium virus Hammer, complete genome	10460-10490	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MG099945	Mycobacterium phage Koko, complete genome	10486-10516	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MT310884	Mycobacterium phage ANI8, complete genome	10360-10390	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NC_022985	Mycobacterium phage Zaka, complete genome	10467-10497	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NC_023607	Mycobacterium phage 40AC, complete genome	12443-12473	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MT310876	Mycobacterium phage VC3, complete genome	10360-10390	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MH779517	Mycobacterium phage Zulu, complete genome	10466-10496	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_LR134463	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 21, complete sequence	94579-94609	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	401403-401433	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	400376-400406	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP007797	Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence	549654-549684	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	318055-318085	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	KU728633	Mycobacterium phage Bipper, complete genome	11900-11930	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MK977701	Mycobacterium phage Cracklewink, complete genome	11900-11930	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP024200	Thalassospira marina strain CSC3H3 plasmid pCSC3H3, complete sequence	358002-358032	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP023549	Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence	700505-700535	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_MF600313	Mycolicibacterium sp. CBMA 213 plasmid pCBMA213_1, complete sequence	240639-240669	9	0.71
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MH047632	Mycobacterium phage Puppy, complete genome	9032-9062	10	0.677
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MH047633	Mycobacterium phage Pistachio, complete genome	8960-8990	10	0.677
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MH051259	Mycobacterium phage TNguyen7, complete genome	9383-9413	10	0.677
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MN062706	Mycobacterium phage Heathen, complete genome	9214-9244	10	0.677
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	KY464936	Mycobacterium phage Idleandcovert, complete genome	9413-9443	10	0.677
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NC_042328	Mycobacterium virus HelDan, complete genome	9466-9496	10	0.677
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MF373840	Mycobacterium phage Fred313, complete genome	9116-9146	10	0.677
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP014769	Hymenobacter sp. PAMC 26554 plasmid unnamed1, complete sequence	144348-144378	10	0.677
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	746522-746552	10	0.677
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	MN224566	Mycobacterium phage Herbertwm, complete genome	9270-9300	10	0.677
NC_018027_2	2.1\|1496090\|31\|NC_018027\|CRISPRCasFinder	1496090-1496120	31	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	1200403-1200433	10	0.677

1. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP015007 (Aminobacter aminovorans strain KCTC 2477 plasmid pAA02, complete sequence) position: , mismatch: 4, identity: 0.871

agccgccg-cggcgtcggccttggcggcagct	CRISPR spacer
-gccgctgacggcgccggccttggcggcggct	Protospacer
 *****.* *****.*************.***

2. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP024924 (Sphingomonas sp. Cra20 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.839

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggccgcggcggcgttggccttggcggcaccg	Protospacer
.***** *******.************* *

3. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP029832 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.839

--agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ccagccg--gcggcctcggccttggcggcggcg	Protospacer
  *****  ***** **************.**

4. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.806

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ctccgccgcggcgtcggcctcgtcggcggat	Protospacer
  ******************.* ****.* *

5. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 6, identity: 0.806

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggtcgccgccgcttcggccttggcggcatcg	Protospacer
.*.****** ** *************** *

6. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 6, identity: 0.806

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggtcgccgccgcttcggccttggcggcatcg	Protospacer
.*.****** ** *************** *

7. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.806

agccgc-cgcggcgtcggccttggcggcagct	CRISPR spacer
-gtcgtgcgcggcggcggccttggcggcggcc	Protospacer
 *.**. ******* *************.**.

8. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 6, identity: 0.806

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ctccgccgcggcgtcggcctcgtcggcggat	Protospacer
  ******************.* ****.* *

9. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 6, identity: 0.806

agccgccgcggcgtcggccttggcggcagct-	CRISPR spacer
cacctccgcggcgtcggtcttggc-gcggctg	Protospacer
 .** ************.****** **.***

10. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 6, identity: 0.806

agccgccgcggcgtcggccttggcggcagct-	CRISPR spacer
cacctccgcggcgtcggtcttggc-gcggctc	Protospacer
 .** ************.****** **.***

11. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP007797 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence) position: , mismatch: 6, identity: 0.806

agccgccgcggcgtcggccttggcggcagct-	CRISPR spacer
cacctccgcggcgtcggtcttggc-gcggctg	Protospacer
 .** ************.****** **.***

12. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 6, identity: 0.806

agccgccgcggcgtcggccttggcggcagct-	CRISPR spacer
cacctccgcggcgtcggtcttggc-gcggctc	Protospacer
 .** ************.****** **.***

13. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 6, identity: 0.806

agccgccgcggcgtcggccttggcggcagct-	CRISPR spacer
cacctccgcggcgtcggtcttggc-gcggctc	Protospacer
 .** ************.****** **.***

14. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 6, identity: 0.806

agccgccgcggcgtcggccttggcggcagct-	CRISPR spacer
cacctccgcggcgtcggtcttggc-gcggctc	Protospacer
 .** ************.****** **.***

15. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MT024869 (Arthrobacter phage Lego, complete genome) position: , mismatch: 7, identity: 0.774

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgccgtggcgtcggccttggcggcgtcg	Protospacer
  .*****.******************. *

16. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP021407 (Celeribacter manganoxidans strain DY25 plasmid pDY25-C, complete sequence) position: , mismatch: 7, identity: 0.774

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ctccgccgcggcggcggcgttggcggcactg	Protospacer
  *********** **** ********* .

17. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MN586026 (Gordonia phage Leonard, complete genome) position: , mismatch: 7, identity: 0.774

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gatcgatgcggcgtcggcctcggcggcagcg	Protospacer
...** .*************.*********

18. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NC_031112 (Gordonia phage Phinally, complete genome) position: , mismatch: 7, identity: 0.774

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gatcgatgcggcgtcggcctcggcggcagcg	Protospacer
...** .*************.*********

19. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 7, identity: 0.774

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ctccgccgcggcgtcggcctcgtcggcggag	Protospacer
  ******************.* ****.*

20. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 7, identity: 0.774

agccgccgcggcgtcggccttggcggcagct--	CRISPR spacer
gcgcgcggcggcgtcggccttggcg--cgctga	Protospacer
.  *** ******************   ***

21. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.774

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ctccgccgcggcgtcggcctcgtcggcggag	Protospacer
  ******************.* ****.*

22. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP049734 (Rhizobium leguminosarum strain A1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

-----agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ccaaaagc-----cggcgtcagccttggcggcagca	Protospacer
     ***     *******.**************

23. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP053444 (Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eB, complete sequence) position: , mismatch: 7, identity: 0.774

-----agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ccaaaagc-----cggcgtcagccttggcggcagcg	Protospacer
     ***     *******.**************

24. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to CP049734 (Rhizobium leguminosarum strain A1 plasmid pRLa11, complete sequence) position: , mismatch: 7, identity: 0.774

-----agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ccaaaagc-----cggcgtcagccttggcggcagca	Protospacer
     ***     *******.**************

25. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP030762 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.774

-----agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ccaaaagc-----cggcgtcagccttggcggcagcg	Protospacer
     ***     *******.**************

26. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP022670 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR5, complete sequence) position: , mismatch: 7, identity: 0.774

-----agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ccaaaagc-----cggcgtcagccttggcggcagcg	Protospacer
     ***     *******.**************

27. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP054035 (Rhizobium sp. JKLM13E plasmid pPR13E04, complete sequence) position: , mismatch: 7, identity: 0.774

-----agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ccaaaagc-----cggcgtcagccttggcggcagca	Protospacer
     ***     *******.**************

28. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MK279899 (Arthrobacter phage Maja, complete genome) position: , mismatch: 7, identity: 0.774

agccg--ccgcggcgtcggccttggcggcagct	CRISPR spacer
--ccggccctcggcgtcggccttggcggcgatg	Protospacer
  ***  ** *******************...

29. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP050096 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b3, complete sequence) position: , mismatch: 7, identity: 0.774

-----agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ccaaaagc-----cggcgtcagccttggcggcagcg	Protospacer
     ***     *******.**************

30. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP050102 (Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b2, complete sequence) position: , mismatch: 7, identity: 0.774

-----agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ccaaaagc-----cggcgtcagccttggcggcagcg	Protospacer
     ***     *******.**************

31. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP050107 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b1, complete sequence) position: , mismatch: 7, identity: 0.774

-----agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ccaaaagc-----cggcgtcagccttggcggcagcg	Protospacer
     ***     *******.**************

32. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_LR134459 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 17, complete sequence) position: , mismatch: 7, identity: 0.774

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cggcgccgcggcgtcgcccttgggggcgggg	Protospacer
 * ************* ****** ***.*

33. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to CP021131 (Meiothermus taiwanensis strain WR-220 plasmid pMtWR-220, complete sequence) position: , mismatch: 7, identity: 0.774

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
tgcggccgcggcttcggccttggcgacgggc	Protospacer
 ** ******** ************.*.* .

34. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP050112 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b5, complete sequence) position: , mismatch: 7, identity: 0.774

-----agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ccaaaagc-----cggcgtcagccttggcggcagcg	Protospacer
     ***     *******.**************

35. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP054024 (Rhizobium sp. JKLM12A2 plasmid pPR12A203, complete sequence) position: , mismatch: 7, identity: 0.774

-----agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ccaaaagc-----cggcgtcagccttggcggcagca	Protospacer
     ***     *******.**************

36. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP017944 (Phyllobacterium zundukense strain Tri-48 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.774

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
agcgtaaccggcgtcggcattggccgcagct	Protospacer
***     ********** ***** ******

37. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP015738 (Shinella sp. HZN7 plasmid pShin-02, complete sequence) position: , mismatch: 7, identity: 0.774

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gccggcctcggcgtcggccttgccggcggat	Protospacer
. * *** ************** ****.* *

38. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NC_009717 (Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence) position: , mismatch: 7, identity: 0.774

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggcggaggcggcttcggccttggcggccgcg	Protospacer
.** *  ***** ************** **

39. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NC_009717 (Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence) position: , mismatch: 7, identity: 0.774

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggcggaggcggcttcggccttggcggccgcg	Protospacer
.** *  ***** ************** **

40. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP014797 (Salipiger profundus strain JLT2016 plasmid pTPRO1, complete sequence) position: , mismatch: 7, identity: 0.774

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
aagtgcggcggcggcggccttggcggcctct	Protospacer
*. .** ****** *************  **

41. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MN234234 (Arthrobacter phage Lymara, complete genome) position: , mismatch: 7, identity: 0.774

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cgcgcccccggcgttggccttggcggcatcc	Protospacer
 **  ** ******.************* *.

42. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NC_023316 (Streptomyces sp. 14R-10 plasmid pZL1, complete sequence) position: , mismatch: 7, identity: 0.774

agccgc-cgcggcgtcggccttggcggcagct	CRISPR spacer
-ctcgcgttcggcctcggccttggcggccgct	Protospacer
  .*** . **** ************** ***

43. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_LN832562 (Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence) position: , mismatch: 7, identity: 0.774

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggcgacggcggcgtcgcccttggcggcggcg	Protospacer
.** .* ********* **********.**

44. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to KX641260 (Mycobacterium phage Stasia, complete genome) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttggacgcggcgtcggccttggcggcatac	Protospacer
  . * **********************  .

45. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to KY083059 (Mycobacterium phage Achebe, complete genome) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttggacgcggcgtcggccttggcggcatac	Protospacer
  . * **********************  .

46. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to KX550442 (Mycobacterium phage Badger, complete genome) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttggacgcggcgtcggccttggcggcatac	Protospacer
  . * **********************  .

47. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MN284905 (Mycobacterium phage AbbysRanger, complete genome) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttggacgcggcgtcggccttggcggcatac	Protospacer
  . * **********************  .

48. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MK359322 (Mycobacterium phage Datway, complete genome) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttggacgcggcgtcggccttggcggcatac	Protospacer
  . * **********************  .

49. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MK875799 (Mycobacterium phage Xena, complete genome) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttggacgcggcgtcggccttggcggcatac	Protospacer
  . * **********************  .

50. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NC_042308 (Mycobacterium virus Backyardigan, complete genome) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttggacgcggcgtcggccttggcggcatac	Protospacer
  . * **********************  .

51. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NC_023709 (Mycobacterium phage Wile, complete genome) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttggacgcggcgtcggccttggcggcatac	Protospacer
  . * **********************  .

52. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggtcgccgcggcgtcggccagggcggcgcgg	Protospacer
.*.****************  ******.

53. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gatcagcgcggcgtcggcctcggcggccgcc	Protospacer
...*. **************.****** **.

54. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggtcgccgcggcgtcggccagggcggcgcgg	Protospacer
.*.****************  ******.

55. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggtcgccgcggcgtcggccagggcggcgcgg	Protospacer
.*.****************  ******.

56. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NC_008381 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL10, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
tatctcgaaggcgtcagccttggcggcagct	Protospacer
 ..* * . ******.***************

57. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP006369 (Aureimonas sp. AU20 plasmid pAU20b, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gcgcgcctcggcgccggccttggcggcggaa	Protospacer
.  **** *****.*************.*

58. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggccgccgccgcgtcggccttgggcgggtcg	Protospacer
.******** *************  * . *

59. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP054615 (Azospirillum oryzae strain KACC 14407 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cgccgccgccgcgccggccttggcgcccagc	Protospacer
 ******** ***.*********** * . .

60. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggccgccgccgcgtcggccttgggcgggtcg	Protospacer
.******** *************  * . *

61. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP033315 (Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggccgccgccgcgtcggccttgggcgggtcg	Protospacer
.******** *************  * . *

62. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP022568 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK04, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ctttggggcggcgtcggcgtcggcggcagct	Protospacer
  ..*  *********** *.**********

63. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MH590593 (Mycobacterium phage Rabinovish, complete genome) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gagcgccgaggtgtcggccttggcggccacc	Protospacer
.. ***** **.*************** .*.

64. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MH045567 (Microbacterium phage Elva, complete genome) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgccgcggcgtcagccttgtcggcgtcc	Protospacer
  .************.****** ****. *.

65. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MN703413 (Arthrobacter phage Powerpuff, complete genome) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgccgtggcgtctgccttggcggcgtcg	Protospacer
  .*****.****** ***********. *

66. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MT024871 (Arthrobacter phage YesChef, complete genome) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgccgtggcgtctgccttggcggcgtcg	Protospacer
  .*****.****** ***********. *

67. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP025017 (Rhizobium leguminosarum strain Norway plasmid pRLN5, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ctttggggcggcgtcggcgtcggcggcagct	Protospacer
  ..*  *********** *.**********

68. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggtcgccgcggcgtcggccagggcggcgcgg	Protospacer
.*.****************  ******.

69. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_LR134456 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 14, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ccacgcctcggcggcggccttggcggtggcg	Protospacer
   **** ***** ************..**

70. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP025613 (Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

-----agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gtgaaag-----gccgtgtcggccttggcggcagcc	Protospacer
     **     ** *.******************.

71. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP011518 (Pandoraea oxalativorans strain DSM 23570 plasmid pPO70-1, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggatgccgcggcgaaggccttggcggcgtcc	Protospacer
.* .*********  ************. *.

72. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP029830 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cagcgaggcggcggcggccttggcggcggcg	Protospacer
 . **  ****** *************.**

73. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP034351 (Streptomyces sp. W1SF4 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ttcggccacggcgtcggcctgggcggcgccg	Protospacer
  * ***.************ ******. *

74. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
atcggccgcggcgacggccatggcggccagg	Protospacer
* * ********* ***** ******* .

75. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gccttcggcggcttctgccttggcggcagcg	Protospacer
. *. * ***** ** **************

76. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NC_016585 (Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cagcgatgcggcggcggccttggcggcggcc	Protospacer
 . ** .****** *************.**.

77. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MH825699 (Streptomyces phage Darolandstone, complete genome) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
accggcggcggcgtcggcctcggcggcgagc	Protospacer
* * ** *************.******.. .

78. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_LR134469 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 27, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gcgcgccgaggcgtcggccgtggcggacgcg	Protospacer
.  ***** ********** ******  **

79. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP015006 (Aminobacter aminovorans strain KCTC 2477 plasmid pAA01, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gtcagtggcggcctcggccttggcggcggca	Protospacer
. * *. ***** **************.**

80. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP015530 (Rhodococcus sp. WB1 plasmid pWB1, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct-----	CRISPR spacer
cgccgccggggagtcggccttggc-----cttgcga	Protospacer
 ******* ** ************     **

81. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP011296 (Rhodococcus erythropolis strain BG43 plasmid pRLCBG43, complete sequence) position: , mismatch: 8, identity: 0.742

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cgcagccgcggcgtcggcctgggcaggtacg	Protospacer
 ** **************** ***.*  .*

82. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MK494117 (Mycobacterium phage Miramae, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcgtcggccttggcggcatac	Protospacer
  .  .**********************  .

83. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MT310879 (Mycobacterium phage MA5, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcgtcggccttggcggcatac	Protospacer
  .  .**********************  .

84. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MK359310 (Mycobacterium phage Katalie136, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcgtcggccttggcggcatac	Protospacer
  .  .**********************  .

85. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MK279898 (Mycobacterium phage Cici, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcgtcggccttggcggcatac	Protospacer
  .  .**********************  .

86. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to KX683423 (Mycobacterium phage BabyRay, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcgtcggccttggcggcatac	Protospacer
  .  .**********************  .

87. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MK494129 (Mycobacterium phage AvatarAhPeg, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcgtcggccttggcggcatac	Protospacer
  .  .**********************  .

88. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MF919498 (Mycobacterium phage Cindaradix, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcgtcggccttggcggcatac	Protospacer
  .  .**********************  .

89. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MK494115 (Mycobacterium phage Bumblebee11, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcgtcggccttggcggcatac	Protospacer
  .  .**********************  .

90. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to KX579975 (Mycobacterium phage Mundrea, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcgtcggccttggcggcatac	Protospacer
  .  .**********************  .

91. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MF668278 (Mycobacterium phage Morpher26, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcgtcggccttggcggcatac	Protospacer
  .  .**********************  .

92. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MG962370 (Mycobacterium phage Kykar, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttggccgcggcgtcagccttggcggcgtac	Protospacer
  . ***********.***********.  .

93. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to AF271693 (Mycobacterium virus Bxb1, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
tttggccgcggcgtcagccttggcggcgtac	Protospacer
  . ***********.***********.  .

94. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MH576975 (Mycobacterium phage Target, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
tttggccgcggcgtcagccttggcggcgtac	Protospacer
  . ***********.***********.  .

95. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to JN699000 (Mycobacterium virus BillKnuckles, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
tttggccgcggcgtcagccttggcggcgtac	Protospacer
  . ***********.***********.  .

96. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NC_002656 (Mycobacterium phage Bxb1, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
tttggccgcggcgtcagccttggcggcgtac	Protospacer
  . ***********.***********.  .

97. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to JN699016 (Mycobacterium phage Kugel, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
tttggccgcggcgtcagccttggcggcgtac	Protospacer
  . ***********.***********.  .

98. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgccgcggcgtcggccagggcggtgggg	Protospacer
  .****************  *****..*

99. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP012477 (Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cagggttgcggcgtcgaccttggcggctgcg	Protospacer
 .  *..*********.********** **

100. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
agccgccgcgccgtcggccatggtcaacgtc	Protospacer
********** ******** ***. .  *..

101. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MG099952 (Mycobacterium phage WunderPhul, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggccgcccac	Protospacer
  .**.****************** **   .

102. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to KX375815 (Mycobacterium phage ToneTone, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggccgcccac	Protospacer
  .**.****************** **   .

103. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to KF560333 (Mycobacterium phage Artemis2UCLA, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggccgcccac	Protospacer
  .**.****************** **   .

104. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MK359360 (Mycobacterium phage Hexamo, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggccgcccac	Protospacer
  .**.****************** **   .

105. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to KX576638 (Mycobacterium phage Gruunaga, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggccgcccac	Protospacer
  .**.****************** **   .

106. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NC_042309 (Mycobacterium virus Gladiator, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggccgcccac	Protospacer
  .**.****************** **   .

107. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MN728683 (Mycobacterium phage Yokurt, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggccgcccac	Protospacer
  .**.****************** **   .

108. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NC_022965 (Mycobacterium phage CloudWang3, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggccgcccac	Protospacer
  .**.****************** **   .

109. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MN813697 (Mycobacterium phage Noelle, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttggacgcggcgtcggccttagcggcatac	Protospacer
  . * ***************.******  .

110. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to JN698999 (Mycobacterium phage Blue7, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggccgcccac	Protospacer
  .**.****************** **   .

111. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MF668288 (Mycobacterium phage Wiks, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggccgcccac	Protospacer
  .**.****************** **   .

112. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MT310885 (Mycobacterium phage AN9, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggcagcccac	Protospacer
  .**.******************.**   .

113. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to AP018476 (Mycobacterium phage C3 DNA, complete sequence) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggcagcccac	Protospacer
  .**.******************.**   .

114. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NC_042318 (Mycobacterium virus Hammer, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggccgcccac	Protospacer
  .**.****************** **   .

115. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MG099945 (Mycobacterium phage Koko, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggccgcccac	Protospacer
  .**.****************** **   .

116. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MT310884 (Mycobacterium phage ANI8, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggcagcccac	Protospacer
  .**.******************.**   .

117. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NC_022985 (Mycobacterium phage Zaka, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggccgcccac	Protospacer
  .**.****************** **   .

118. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NC_023607 (Mycobacterium phage 40AC, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggccgcccac	Protospacer
  .**.****************** **   .

119. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MT310876 (Mycobacterium phage VC3, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggcagcccac	Protospacer
  .**.******************.**   .

120. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MH779517 (Mycobacterium phage Zulu, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttcgtcgcggcgtcggccttggccgcccac	Protospacer
  .**.****************** **   .

121. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_LR134463 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 21, complete sequence) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gatcgccgcggcgtcggcctcggaggccagg	Protospacer
...*****************.** *** .

122. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gtccgccgcggcctccgccttggcgatctgt	Protospacer
. ********** ** *********..   *

123. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gtccgccgcggcctccgccttggcgatctgt	Protospacer
. ********** ** *********..   *

124. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP007797 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gtccgccgcggcctccgccttggcgatctgt	Protospacer
. ********** ** *********..   *

125. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cacggcctcggcgacggccttggcggcgatc	Protospacer
 .* *** ***** *************....

126. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to KU728633 (Mycobacterium phage Bipper, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggcagccgcggcctcggccttggcctggacg	Protospacer
.** ******** ***********   ..*

127. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MK977701 (Mycobacterium phage Cracklewink, complete genome) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggcagccgcggcctcggccttggcctggacg	Protospacer
.** ******** ***********   ..*

128. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP024200 (Thalassospira marina strain CSC3H3 plasmid pCSC3H3, complete sequence) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gtgcttttcggcgtcggccttgccggcggct	Protospacer
.  * .. ************** ****.***

129. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP023549 (Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ggccaccgcggcctcggccttggcctgactg	Protospacer
.***.******* ***********   * .

130. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_MF600313 (Mycolicibacterium sp. CBMA 213 plasmid pCBMA213_1, complete sequence) position: , mismatch: 9, identity: 0.71

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
tcaggccgcggcggcggcgttggcggccgaa	Protospacer
    ********* **** ******** *

131. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MH047632 (Mycobacterium phage Puppy, complete genome) position: , mismatch: 10, identity: 0.677

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcgtcggccttcgcggcatac	Protospacer
  .  .*************** ******  .

132. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MH047633 (Mycobacterium phage Pistachio, complete genome) position: , mismatch: 10, identity: 0.677

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcgtcggccttcgcggcatac	Protospacer
  .  .*************** ******  .

133. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MH051259 (Mycobacterium phage TNguyen7, complete genome) position: , mismatch: 10, identity: 0.677

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcgtcggccttcgcggcatac	Protospacer
  .  .*************** ******  .

134. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MN062706 (Mycobacterium phage Heathen, complete genome) position: , mismatch: 10, identity: 0.677

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcatcggccttggcggcatac	Protospacer
  .  .******.***************  .

135. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to KY464936 (Mycobacterium phage Idleandcovert, complete genome) position: , mismatch: 10, identity: 0.677

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcgtcggccttcgcggcatac	Protospacer
  .  .*************** ******  .

136. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NC_042328 (Mycobacterium virus HelDan, complete genome) position: , mismatch: 10, identity: 0.677

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcgtcggccttcgcggcatac	Protospacer
  .  .*************** ******  .

137. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MF373840 (Mycobacterium phage Fred313, complete genome) position: , mismatch: 10, identity: 0.677

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttgctcgcggcatcggccttggcggcatac	Protospacer
  .  .******.***************  .

138. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP014769 (Hymenobacter sp. PAMC 26554 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.677

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
ccgggccgcggcggcgaccttggcggcccac	Protospacer
    ********* **.**********   .

139. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 10, identity: 0.677

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gaggaaggcggcgccggccttggcggcggcg	Protospacer
..  .  ******.*************.**

140. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to MN224566 (Mycobacterium phage Herbertwm, complete genome) position: , mismatch: 10, identity: 0.677

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
cttggccgctgcgtcggccttggccgcgtac	Protospacer
  . ***** ************** **.  .

141. spacer 2.1|1496090|31|NC_018027|CRISPRCasFinder matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 10, identity: 0.677

agccgccgcggcgtcggccttggcggcagct	CRISPR spacer
gtccggctcggcgtcggccttggcgatgcgc	Protospacer
. *** * *****************...  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1843952 : 1851662

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014815047.1\|1843952_1844816_+	SDR family oxidoreductase	W8CYX9	Bacillus_phage	1.3e-06	37.2
WP_014815048.1\|1844819_1845986_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	1.9e-53	36.7
WP_014815049.1\|1845996_1847082_-	DNA polymerase IV	F1C5A5	Cronobacter_phage	3.0e-16	26.7
WP_014815050.1\|1847078_1847669_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_014815051.1\|1847783_1848335_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	1.2e-08	35.4
WP_014815052.1\|1848809_1849049_+	redoxin NrdH	V5UN81	Mycobacterium_phage	8.8e-22	66.2
WP_014815053.1\|1849080_1849527_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	NA	NA	NA	NA
WP_014815054.1\|1849493_1851662_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	V9VI16	Lactococcus_phage	1.4e-206	51.5

DBSCAN-SWA_2

2528859 : 2536765

Mycobacterium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014815706.1\|2528859_2529654_+	Fe-S cluster assembly ATPase SufC	W8CYL7	Bacillus_phage	9.9e-09	27.4
WP_014815707.1\|2529655_2530951_+	cysteine desulfurase	Q2XUY6	environmental_halophage	7.0e-105	47.5
WP_014815708.1\|2530953_2531415_+	SUF system NifU family Fe-S cluster assembly protein	A0A0K1LSF9	Mycobacterium_phage	2.9e-21	44.9
WP_041781882.1\|2531453_2531789_+	metal-sulfur cluster assembly factor	NA	NA	NA	NA
WP_014815710.1\|2531795_2532320_+	hypothetical protein	NA	NA	NA	NA
WP_014815711.1\|2532367_2532736_+	thioredoxin	A0A1J0GW78	Streptomyces_phage	6.4e-11	35.1
WP_014815712.1\|2532774_2533590_+	enoyl-CoA hydratase	NA	NA	NA	NA
WP_014815713.1\|2533681_2535310_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L0W2	Tupanvirus	1.4e-33	24.9
WP_014815714.1\|2535484_2536765_+	PE-PPE domain-containing protein	A0A222ZKN7	Mycobacterium_phage	2.3e-15	32.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_018022

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

4017 : 52673

Mycobacterium_phage(58.33%)

integrase,transposase

attL 13899:13914|attR 54016:54031

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014805312.1\|4017_4314_+\|transposase	transposase	NA	NA	NA	NA
WP_081495180.1\|4319_4943_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	9.7e-28	43.5
WP_014805314.1\|5618_6824_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_014805315.1\|8241_9771_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_014805316.1\|9767_10565_+	ATP-binding protein	NA	NA	NA	NA
WP_014805317.1\|12189_12744_+	hypothetical protein	NA	NA	NA	NA
WP_158021525.1\|12915_13311_+	relaxase domain-containing protein	NA	NA	NA	NA
WP_014805319.1\|13355_13625_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_014805320.1\|13621_13900_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
13899:13914	attL	NA	NA	NA	NA
WP_014805321.1\|14241_14493_+	type II toxin-antitoxin system ParD family antitoxin	NA	NA	NA	NA
WP_041783793.1\|14489_14786_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_162131316.1\|14887_16438_-	hypothetical protein	NA	NA	NA	NA
WP_014805325.1\|17485_17929_-\|transposase	transposase	NA	NA	NA	NA
WP_014805326.1\|17925_20100_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_014805327.1\|20096_21278_-\|integrase	tyrosine-type recombinase/integrase	A0A1S5S7K9	Streptococcus_phage	1.1e-06	54.3
WP_158021526.1\|21383_22229_-	hypothetical protein	NA	NA	NA	NA
WP_158021527.1\|22553_23042_-	hypothetical protein	NA	NA	NA	NA
WP_014805330.1\|24318_25911_+	ParB/RepB/Spo0J family partition protein	I3NLC2	Bifidobacterium_phage	1.5e-11	33.3
WP_014805331.1\|26240_27113_+	ParA family protein	NA	NA	NA	NA
WP_041783857.1\|27199_27382_+	hypothetical protein	NA	NA	NA	NA
WP_158021567.1\|27824_28055_-	hypothetical protein	NA	NA	NA	NA
WP_014805334.1\|28433_29246_-	hypothetical protein	NA	NA	NA	NA
WP_014805335.1\|29365_29872_-	hypothetical protein	NA	NA	NA	NA
WP_158021528.1\|30157_30430_+	hypothetical protein	NA	NA	NA	NA
WP_014805337.1\|30452_32408_-	hypothetical protein	V5UNW4	Mycobacterium_phage	2.0e-140	44.2
WP_014805339.1\|32973_33849_+	DUF2637 domain-containing protein	A0A1D8EW93	Mycobacterium_phage	1.4e-11	38.1
WP_014805341.1\|35220_36675_-	ParB N-terminal domain-containing protein	S5YZ97	Mycobacterium_phage	4.7e-81	42.4
WP_081495183.1\|37528_38113_-	nuclease	V5UN65	Mycobacterium_phage	2.2e-37	47.6
WP_014805343.1\|38109_38349_-	hypothetical protein	NA	NA	NA	NA
WP_158021529.1\|38422_38740_-	hypothetical protein	NA	NA	NA	NA
WP_014805344.1\|39028_39460_-	PIN domain nuclease	NA	NA	NA	NA
WP_014805345.1\|39456_39678_-	hypothetical protein	NA	NA	NA	NA
WP_041783859.1\|39768_40050_+	hypothetical protein	NA	NA	NA	NA
WP_158021530.1\|40072_40561_-	DNA-binding protein	NA	NA	NA	NA
WP_014805347.1\|40553_41789_-	helix-turn-helix transcriptional regulator	V5UNB6	Mycobacterium_phage	2.8e-10	40.5
WP_158021531.1\|41922_42855_-\|integrase	tyrosine-type recombinase/integrase	G1JX48	Mycobacterium_phage	2.3e-09	25.3
WP_014805349.1\|42974_44294_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	7.9e-221	88.2
WP_014805351.1\|44608_44956_-	DUF2384 domain-containing protein	NA	NA	NA	NA
WP_158021568.1\|45587_46796_+	SIR2 family protein	NA	NA	NA	NA
WP_014805353.1\|46863_47739_+	DNA processing protein DprA	S6BFL3	Thermus_phage	3.6e-20	38.9
WP_014805354.1\|47798_48494_+	putative amidophosphoribosyltransferase	NA	NA	NA	NA
WP_158021532.1\|48656_49361_+	hypothetical protein	NA	NA	NA	NA
WP_014805356.1\|49763_51170_-	hypothetical protein	NA	NA	NA	NA
WP_014805357.1\|51243_51591_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_051053650.1\|51587_52673_-\|integrase	site-specific integrase	A0A0K2CP59	Brevibacillus_phage	6.3e-06	23.3
54016:54031	attR	NA	NA	NA	NA

DBSCAN-SWA_2

79045 : 145535

Mycobacterium_phage(30.0%)

protease,integrase,transposase

attL 91929:91988|attR 131843:133479

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014805385.1\|79045_80101_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_051053650.1\|80798_81884_+\|integrase	site-specific integrase	A0A0K2CP59	Brevibacillus_phage	6.3e-06	23.3
WP_014805357.1\|81880_82228_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014805356.1\|82301_83708_+	hypothetical protein	NA	NA	NA	NA
WP_158021536.1\|84067_85549_-	ThiF family adenylyltransferase	NA	NA	NA	NA
WP_014805387.1\|85563_85965_-	hypothetical protein	NA	NA	NA	NA
WP_014805388.1\|85961_86606_-	hypothetical protein	NA	NA	NA	NA
WP_014805389.1\|86716_87220_-	hypothetical protein	NA	NA	NA	NA
WP_014805390.1\|87225_87753_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_158021537.1\|87756_88458_-	hypothetical protein	NA	NA	NA	NA
WP_014805392.1\|88651_88831_-	hypothetical protein	NA	NA	NA	NA
WP_041783806.1\|88946_90044_-	dihydrodipicolinate reductase	NA	NA	NA	NA
WP_014805394.1\|90076_90388_-	signal transduction histidine kinase	NA	NA	NA	NA
WP_014805395.1\|90750_91548_-	DUF2637 domain-containing protein	A0A222ZMJ5	Mycobacterium_phage	2.7e-22	37.7
WP_041783807.1\|91544_91769_-	XRE family transcriptional regulator	NA	NA	NA	NA
91929:91988	attL	NA	NA	NA	NA
WP_081495200.1\|92090_93422_+\|transposase	IS1380 family transposase	A0A222ZN33	Mycobacterium_phage	7.9e-160	64.6
WP_014805397.1\|93727_95080_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	U5N3F9	Enterobacteria_phage	1.8e-18	25.6
WP_014805398.1\|95076_95934_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	6.4e-38	36.9
WP_014805399.1\|96454_97726_+	hypothetical protein	NA	NA	NA	NA
WP_158021538.1\|98209_98740_+	hypothetical protein	NA	NA	NA	NA
WP_014805401.1\|98929_99673_+	Abi-like protein	NA	NA	NA	NA
WP_041783869.1\|100344_100953_+	hypothetical protein	NA	NA	NA	NA
WP_158021539.1\|100957_101101_+	hypothetical protein	NA	NA	NA	NA
WP_041783808.1\|101097_101619_+	hypothetical protein	NA	NA	NA	NA
WP_014805404.1\|101639_102080_-	VOC family protein	NA	NA	NA	NA
WP_014805405.1\|102547_103264_+	type 1 glutamine amidotransferase domain-containing protein	NA	NA	NA	NA
WP_158021571.1\|103961_104921_+	CdaR family transcriptional regulator	NA	NA	NA	NA
WP_014805407.1\|104923_106336_-	aldehyde dehydrogenase family protein	A0A1X9I5D4	Streptococcus_phage	5.1e-08	30.1
WP_014805408.1\|106532_108092_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_014805409.1\|108129_109065_+	TIGR03564 family F420-dependent LLM class oxidoreductase	NA	NA	NA	NA
WP_014805410.1\|109137_109425_+	hypothetical protein	NA	NA	NA	NA
WP_006247536.1\|109743_109974_+	hypothetical protein	NA	NA	NA	NA
WP_014805411.1\|110273_111779_-	argininosuccinate lyase	NA	NA	NA	NA
WP_014805412.1\|111775_112750_-	D-cysteine desulfhydrase family protein	NA	NA	NA	NA
WP_006247532.1\|114116_115016_-	hypothetical protein	NA	NA	NA	NA
WP_014805413.1\|115012_115789_-	phosphohydrolase	NA	NA	NA	NA
WP_041783870.1\|116082_117459_+	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	7.9e-06	26.4
WP_014805415.1\|117462_118206_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	2.2e-10	27.7
WP_014805416.1\|118221_118995_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	3.0e-18	32.5
WP_014805417.1\|119021_119942_+	CoA transferase subunit A	NA	NA	NA	NA
WP_014805418.1\|119938_120769_+	glutaconate CoA-transferase	NA	NA	NA	NA
WP_014805419.1\|120762_122241_+	acyl-CoA synthetase (NDP forming)	NA	NA	NA	NA
WP_051053651.1\|122237_122858_+	hypothetical protein	NA	NA	NA	NA
WP_014805420.1\|123700_125266_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_014805421.1\|125508_126531_-	2Fe-2S iron-sulfur cluster binding domain-containing protein	NA	NA	NA	NA
WP_014805422.1\|126530_128036_-	methane monooxygenase	NA	NA	NA	NA
WP_014805423.1\|128082_128403_-	MmoB/DmpM family protein	NA	NA	NA	NA
WP_014805424.1\|128399_129434_-	Methane/Phenol/Toluene Hydroxylase	NA	NA	NA	NA
WP_014805425.1\|129610_130534_+	GAF domain-containing protein	NA	NA	NA	NA
WP_014805427.1\|131221_131950_-	hypothetical protein	NA	NA	NA	NA
WP_081495200.1\|132004_133336_+\|transposase	IS1380 family transposase	A0A222ZN33	Mycobacterium_phage	7.9e-160	64.6
WP_014805429.1\|134947_140755_-	relaxase domain-containing protein	NA	NA	NA	NA
131843:133479	attR	NA	NA	NA	NA
WP_014805431.1\|141587_142085_+	hypothetical protein	NA	NA	NA	NA
WP_014805432.1\|142189_142642_-	hypothetical protein	NA	NA	NA	NA
WP_014805433.1\|143034_143355_-	hypothetical protein	NA	NA	NA	NA
WP_014805434.1\|143446_144412_-	DUF4192 domain-containing protein	NA	NA	NA	NA
WP_158021540.1\|144757_144901_+	hypothetical protein	NA	NA	NA	NA
WP_158021541.1\|144905_145535_-\|protease	serine protease	NA	NA	NA	NA

DBSCAN-SWA_3

209159 : 282252

Mycobacterium_phage(61.54%)

protease,transposase,integrase

attL 281109:281168|attR 301556:301746

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_158021572.1\|209159_210665_-\|protease	type VII secretion-associated serine protease mycosin	V5UPA7	Mycobacterium_phage	2.0e-63	37.9
WP_014805493.1\|210826_212341_-	type VII secretion integral membrane protein EccD	NA	NA	NA	NA
WP_014805495.1\|214266_215223_-	ESX secretion-associated protein EspG	NA	NA	NA	NA
WP_014805496.1\|215236_215527_-	hypothetical protein	NA	NA	NA	NA
WP_014805497.1\|215564_215864_-	hypothetical protein	NA	NA	NA	NA
WP_014805498.1\|215945_217313_-	PPE domain-containing protein	NA	NA	NA	NA
WP_041783821.1\|217317_217617_-	PE domain-containing protein	NA	NA	NA	NA
WP_014805501.1\|218206_222367_-	type VII secretion protein EccCa	A0A142F150	Bacillus_phage	1.2e-17	27.8
WP_014805502.1\|222373_223852_-	type VII secretion protein EccB	V5UN45	Mycobacterium_phage	2.0e-63	35.6
WP_014805503.1\|223990_226414_-	hypothetical protein	V5UPQ7	Mycobacterium_phage	3.8e-19	29.9
WP_014805504.1\|226413_227031_-	hypothetical protein	NA	NA	NA	NA
WP_014805505.1\|227027_227375_-	hypothetical protein	NA	NA	NA	NA
WP_158021573.1\|227388_227763_-	hypothetical protein	NA	NA	NA	NA
WP_014805507.1\|228151_228556_-	hypothetical protein	NA	NA	NA	NA
WP_014805508.1\|228552_230346_-	hypothetical protein	NA	NA	NA	NA
WP_014805509.1\|230354_230654_-	hypothetical protein	NA	NA	NA	NA
WP_014805510.1\|230661_230976_-	ESX-1 secretion-associated protein	NA	NA	NA	NA
WP_158021574.1\|230979_232617_-	DUF4226 domain-containing protein	V5UPX1	Mycobacterium_phage	6.1e-13	47.8
WP_158021548.1\|232811_232961_-	hypothetical protein	NA	NA	NA	NA
WP_158021549.1\|234700_235237_+	hypothetical protein	NA	NA	NA	NA
WP_014805512.1\|235519_236227_-	hypothetical protein	NA	NA	NA	NA
WP_041783827.1\|236223_237150_-	ParA family protein	V5UP47	Mycobacterium_phage	7.7e-05	30.3
WP_014805514.1\|237954_238779_-	hypothetical protein	NA	NA	NA	NA
WP_014805515.1\|239268_239982_+	ParA family protein	A2I303	Vibrio_virus	7.8e-05	29.4
WP_014805516.1\|239981_240824_+	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_014805517.1\|240827_241268_-	hypothetical protein	NA	NA	NA	NA
WP_014805518.1\|241458_241632_+	hypothetical protein	NA	NA	NA	NA
WP_158021575.1\|242332_243301_+	hypothetical protein	NA	NA	NA	NA
WP_014805520.1\|243731_246308_-	S8 family peptidase	NA	NA	NA	NA
WP_014805521.1\|246304_247267_-	ATP-binding protein	R4TQL5	Phaeocystis_globosa_virus	2.9e-15	33.0
WP_051053686.1\|248383_248776_+	hypothetical protein	A0A142F2N0	Mycobacterium_phage	3.1e-24	44.1
WP_014805523.1\|248798_249455_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014805524.1\|249842_250226_+	WhiB family transcriptional regulator	NA	NA	NA	NA
WP_014805525.1\|250218_250587_+	hypothetical protein	NA	NA	NA	NA
WP_041783829.1\|250568_250832_+	hypothetical protein	NA	NA	NA	NA
WP_014805526.1\|250828_251347_+	hypothetical protein	A0A1C9EHH1	Mycobacterium_phage	1.1e-21	41.5
WP_014805527.1\|251343_251601_+	hypothetical protein	NA	NA	NA	NA
WP_014805528.1\|251597_252377_+	hypothetical protein	NA	NA	NA	NA
WP_158021576.1\|252598_257854_+	DEAD/DEAH box helicase family protein	A0A240F4T3	Ochrobactrum_phage	3.5e-195	30.8
WP_158021550.1\|258039_258618_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_051053661.1\|258713_259580_-	DUF4226 domain-containing protein	NA	NA	NA	NA
WP_014805532.1\|260045_261083_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_162131317.1\|261287_261545_-	hypothetical protein	NA	NA	NA	NA
WP_158021551.1\|261541_262096_-	hypothetical protein	NA	NA	NA	NA
WP_014805535.1\|262315_263398_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_014805536.1\|263829_264939_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_081495186.1\|266209_266875_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_051053687.1\|267020_267884_+	CoA transferase	NA	NA	NA	NA
WP_014805539.1\|267880_269056_+	thiolase family protein	NA	NA	NA	NA
WP_081495187.1\|270616_271510_+	hypothetical protein	NA	NA	NA	NA
WP_014805541.1\|271517_272666_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_014805542.1\|272696_273455_+	SDR family NAD(P)-dependent oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	4.0e-07	32.8
WP_051053663.1\|275051_275282_-	hypothetical protein	NA	NA	NA	NA
WP_014805543.1\|275753_277355_+	phosphomethylpyrimidine synthase ThiC	NA	NA	NA	NA
WP_014805545.1\|278897_279410_+	hypothetical protein	NA	NA	NA	NA
WP_162131313.1\|280961_281108_-	hypothetical protein	NA	NA	NA	NA
WP_081495188.1\|281067_281253_-\|transposase	transposase	NA	NA	NA	NA
281109:281168	attL	NA	NA	NA	NA
WP_158021577.1\|281313_282252_-\|integrase	tyrosine-type recombinase/integrase	A0A1D8EV03	Mycobacterium_phage	1.1e-06	28.0
WP_158021577.1\|281313_282252_-\|integrase	tyrosine-type recombinase/integrase	A0A1D8EV03	Mycobacterium_phage	1.1e-06	28.0
301556:301746	attR	NA	NA	NA	NA

DBSCAN-SWA_4

292428 : 345339

Erysipelothrix_phage(40.0%)

protease,integrase,transposase

attL 308620:308635|attR 347491:347506

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014805466.1\|292428_293946_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_014805465.1\|293942_294719_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.1e-11	29.3
WP_014805535.1\|297030_298113_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_048471619.1\|299181_299982_-	TM helix repeat-containing protein	NA	NA	NA	NA
WP_051053665.1\|300852_301278_+	hypothetical protein	NA	NA	NA	NA
WP_081495188.1\|301470_301656_+\|transposase	transposase	NA	NA	NA	NA
WP_162131313.1\|301615_301762_+	hypothetical protein	NA	NA	NA	NA
WP_158021554.1\|302646_302937_-	hypothetical protein	NA	NA	NA	NA
WP_014805555.1\|305459_306416_+\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_041783833.1\|307094_307754_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_048471611.1\|307913_308369_+	PaaI family thioesterase	NA	NA	NA	NA
WP_014805558.1\|308365_309037_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
308620:308635	attL	NA	NA	NA	NA
WP_014805559.1\|309647_312746_+	MMPL family transporter	NA	NA	NA	NA
WP_014805453.1\|313132_314572_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_014805452.1\|314637_316407_+	hypothetical protein	NA	NA	NA	NA
WP_014805451.1\|316403_318518_+	hypothetical protein	NA	NA	NA	NA
WP_014805450.1\|318514_318937_+	hypothetical protein	NA	NA	NA	NA
WP_014805449.1\|318982_320338_-	NAD(P)/FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	2.2e-40	28.6
WP_014805448.1\|320387_321029_-	organomercurial lyase MerB	NA	NA	NA	NA
WP_014805447.1\|321056_322442_-	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	8.7e-45	29.7
WP_079633045.1\|322607_322916_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014805445.1\|322937_323255_+	hypothetical protein	NA	NA	NA	NA
WP_014805444.1\|323258_323849_+	redoxin domain-containing protein	NA	NA	NA	NA
WP_014805443.1\|323845_324772_+	cytochrome c biogenesis protein	NA	NA	NA	NA
WP_014805442.1\|325196_325604_-	heavy metal-responsive transcriptional regulator	NA	NA	NA	NA
WP_099459217.1\|325886_327086_+	MFS transporter	NA	NA	NA	NA
WP_158021555.1\|327573_328464_+	hypothetical protein	NA	NA	NA	NA
WP_041783834.1\|328628_329750_-	hypothetical protein	NA	NA	NA	NA
WP_014805561.1\|330565_330826_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014805562.1\|330806_331103_-	hypothetical protein	NA	NA	NA	NA
WP_014805563.1\|331234_331783_-	hypothetical protein	NA	NA	NA	NA
WP_014805565.1\|332631_333207_+	hypothetical protein	NA	NA	NA	NA
WP_014805566.1\|333466_334828_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_014805567.1\|334872_335646_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_014805568.1\|335694_336108_-	DUF302 domain-containing protein	NA	NA	NA	NA
WP_014805569.1\|336143_336413_-	metal-sensitive transcriptional regulator	NA	NA	NA	NA
WP_014805570.1\|336467_337670_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_014805571.1\|337709_339089_-	MBL fold metallo-hydrolase	A0A2H4PQR9	Staphylococcus_phage	1.4e-05	34.1
WP_014805572.1\|339296_339902_+	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_014805574.1\|340245_340515_+	metal-sensitive transcriptional regulator	NA	NA	NA	NA
WP_158021578.1\|340607_343040_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_014805576.1\|343117_344284_-\|integrase	tyrosine-type recombinase/integrase	W8EHC2	Mycobacterium_phage	1.0e-06	28.3
WP_014805577.1\|344688_345339_-\|protease	CAAX amino protease	NA	NA	NA	NA
347491:347506	attR	NA	NA	NA	NA

DBSCAN-SWA_5

505081 : 554861

Erysipelothrix_phage(28.57%)

integrase,transposase

attL 520712:520730|attR 553283:553301

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014805535.1\|505081_506164_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_162131315.1\|506242_506419_-	hypothetical protein	NA	NA	NA	NA
WP_014805563.1\|506733_507282_+	hypothetical protein	NA	NA	NA	NA
WP_014805562.1\|507413_507710_+	hypothetical protein	NA	NA	NA	NA
WP_014805561.1\|507690_507951_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_099459217.1\|509017_510217_-	MFS transporter	NA	NA	NA	NA
WP_014805442.1\|510499_510907_+	heavy metal-responsive transcriptional regulator	NA	NA	NA	NA
WP_014805443.1\|511331_512258_-	cytochrome c biogenesis protein	NA	NA	NA	NA
WP_014805444.1\|512254_512845_-	redoxin domain-containing protein	NA	NA	NA	NA
WP_014805445.1\|512848_513166_-	hypothetical protein	NA	NA	NA	NA
WP_079633045.1\|513187_513496_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014805447.1\|513661_515047_+	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	8.7e-45	29.7
WP_014805448.1\|515074_515716_+	organomercurial lyase MerB	NA	NA	NA	NA
WP_014805449.1\|515765_517121_+	NAD(P)/FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	2.2e-40	28.6
WP_014805450.1\|517166_517589_-	hypothetical protein	NA	NA	NA	NA
WP_014805451.1\|517585_519700_-	hypothetical protein	NA	NA	NA	NA
WP_014805452.1\|519696_521466_-	hypothetical protein	NA	NA	NA	NA
520712:520730	attL	NA	NA	NA	NA
WP_014805453.1\|521531_522971_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_014805727.1\|523266_524844_+	ParB N-terminal domain-containing protein	V5UQR1	Mycobacterium_phage	2.4e-62	34.1
WP_014805728.1\|525118_525370_+	glutaredoxin-like protein NrdH	V5UN81	Mycobacterium_phage	7.9e-21	64.6
WP_014805729.1\|525415_525703_+	hypothetical protein	NA	NA	NA	NA
WP_014805730.1\|525707_526241_+	hypothetical protein	NA	NA	NA	NA
WP_014805731.1\|526366_526870_-	hypothetical protein	NA	NA	NA	NA
WP_014805732.1\|526963_527149_-	hypothetical protein	NA	NA	NA	NA
WP_041783844.1\|527179_527674_-	hypothetical protein	NA	NA	NA	NA
WP_014805734.1\|527997_533844_+	relaxase domain-containing protein	NA	NA	NA	NA
WP_051053675.1\|533840_534452_-	hypothetical protein	A0A291AUV6	Sinorhizobium_phage	6.8e-26	38.7
WP_014805363.1\|534980_536012_-	2Fe-2S iron-sulfur cluster binding domain-containing protein	NA	NA	NA	NA
WP_014805364.1\|536023_536341_-	monooxygenase	NA	NA	NA	NA
WP_014805365.1\|536337_537429_-	monooxygenase	NA	NA	NA	NA
WP_014805366.1\|537428_538967_-	monooxygenase	NA	NA	NA	NA
WP_051053682.1\|539221_539800_+	response regulator transcription factor	NA	NA	NA	NA
WP_014805368.1\|539771_540872_-	GAF domain-containing protein	NA	NA	NA	NA
WP_014805369.1\|541220_542459_+	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_041783799.1\|542485_543862_+	histidine kinase	NA	NA	NA	NA
WP_014805736.1\|543867_544548_+	response regulator transcription factor	NA	NA	NA	NA
WP_014805737.1\|544540_545422_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_014805738.1\|545616_545721_+	mycofactocin precursor	NA	NA	NA	NA
WP_014805739.1\|545723_545984_+	mycofactocin biosynthesis chaperone MftB	NA	NA	NA	NA
WP_014805740.1\|545980_547147_+	mycofactocin radical SAM maturase	A0A1B1IVD8	uncultured_Mediterranean_phage	5.0e-09	21.9
WP_014805741.1\|547160_548336_+	mycofactocin biosynthesis FMN-dependent deaminase MftD	NA	NA	NA	NA
WP_014805327.1\|549437_550619_+\|integrase	tyrosine-type recombinase/integrase	A0A1S5S7K9	Streptococcus_phage	1.1e-06	54.3
WP_014805742.1\|550615_552790_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_014805325.1\|552786_553230_+\|transposase	transposase	NA	NA	NA	NA
WP_014805743.1\|553625_554861_-\|transposase	IS21 family transposase	NA	NA	NA	NA
553283:553301	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_018023

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_018027

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NC_018022

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection