CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_018028	Pseudomonas stutzeri CCUG 29243, complete sequence	3 crisprs	csa3,DEDDh,cas3,RT,DinG,WYL	0	0	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_018028_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018028_1

1136679-1136767

Orphan

Consensus_repeat	Method
CCACCCTTGCGGCCGGCCTCGGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_018028_1

>merge|NC_018028|1|1136679-1136767|CRISPRCasFinder
CCACCCTTGCGGCCGGCCTCGGAGGCCTTCTCGCGGTCGTTGGCGAAGTTGCCGCCGCTGTTGTGACCACCCTTGCGGCCGGCCTCGGA

>NC_018028|1|1|1136679-1136767|CRISPRCasFinder
CCACCCTTGCGGCCGGCCTCGGA	GGCCTTCTCGCGGTCGTTGGCGAAGTTGCCGCCGCTGTTGTGA
CCACCCTTGCGGCCGGCCTCGGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_018028.1\|WP_014819386.1\|1127538_1128120_-\|superoxide-dismutase	unknown	unknown	gnl\|CDD\|182534
NC_018028.1\|WP_014819403.1\|1146777_1147188_-\|hydroxyisourate-hydrolase	unknown	unknown	gnl\|CDD\|274364
NC_018028.1\|WP_014819391.1\|1131701_1133612_-\|autotransporter-domain-containing-esterase	unknown	unknown	gnl\|CDD\|238883
NC_018028.1\|WP_014819390.1\|1130740_1131646_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
NC_018028.1\|WP_014819398.1\|1140494_1141766_-\|glycerate-kinase	unknown	unknown	gnl\|CDD\|225254
NC_018028.1\|WP_014819387.1\|1128520_1129129_-\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NC_018028.1\|WP_162836508.1\|1129213_1130110_+\|ArgP/LysG-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|235144
NC_018028.1\|WP_014819396.1\|1138786_1139011_+\|DUF2188-domain-containing-protein	unknown	unknown	gnl\|CDD\|378323
NC_018028.1\|WP_014819401.1\|1143972_1145754_-\|glyoxylate-carboligase	unknown	unknown	gnl\|CDD\|183066
NC_018028.1\|WP_014819402.1\|1145863_1146772_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NC_018028.1\|WP_014819384.1\|1124378_1125062_-\|spermidine-synthase	unknown	unknown	gnl\|CDD\|223498
NC_018028.1\|WP_014819389.1\|1130114_1130381_-\|hypothetical-protein	unknown	unknown	unknown
NC_018028.1\|WP_014819392.1\|1133952_1135149_+\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
NC_018028.1\|WP_014819393.1\|1135152_1136355_-\|nicotinate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235406
NC_018028.1\|WP_014819399.1\|1142092_1142983_-\|2-hydroxy-3-oxopropionate-reductase	unknown	unknown	gnl\|CDD\|185019
NC_018028.1\|WP_014819385.1\|1125193_1127254_-\|GGDEF-and-EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NC_018028.1\|WP_014819397.1\|1139046_1140462_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|180487
NC_018028.1\|WP_014819394.1\|1137049_1137283_-\|hypothetical-protein	unknown	unknown	unknown
NC_018028.1\|WP_014819395.1\|1137334_1138513_-\|NO-inducible-flavohemoprotein	unknown	unknown	gnl\|CDD\|237337
NC_018028.1\|WP_014819400.1\|1143011_1143794_-\|hydroxypyruvate-isomerase	unknown	unknown	gnl\|CDD\|226149

Protein	Function_ID	Function_description	E-value
NC_018028.1\|WP_014819386.1\|1127538_1128120_-\|superoxide-dismutase	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	2.01043e-111
NC_018028.1\|WP_014819403.1\|1146777_1147188_-\|hydroxyisourate-hydrolase	gnl\|CDD\|274364	TIGR02962, Probable_5-hydroxyisourate_hydrolase_R09H10.3, hydroxyisourate hydrolase. Members of this family, hydroxyisourate hydrolase, represent a distinct clade of transthyretin-related proteins. Bacterial members typically are encoded next to ureidoglycolate hydrolase and often near either xanthine dehydrogenase or xanthine/uracil permease genes and have been demonstrated to have hydroxyisourate hydrolase activity. In eukaryotes, a clade separate from the transthyretins (a family of thyroid-hormone binding proteins) has also been shown to have HIU hydrolase activity in urate catabolizing organisms. Transthyretin, then, would appear to be the recently diverged paralog of the more ancient HIUH family. [Purines, pyrimidines, nucleosides, and nucleotides, Other].	1.0803e-53
NC_018028.1\|WP_014819391.1\|1131701_1133612_-\|autotransporter-domain-containing-esterase	gnl\|CDD\|238883	cd01847, Triacylglycerol_lipase_like, Triacylglycerol lipase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases. Members of this subfamily might hydrolyze triacylglycerol into diacylglycerol and fatty acid anions.	1.88359e-50
NC_018028.1\|WP_014819390.1\|1130740_1131646_+\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.000173229
NC_018028.1\|WP_014819398.1\|1140494_1141766_-\|glycerate-kinase	gnl\|CDD\|225254	COG2379, GckA, Putative glycerate kinase [Carbohydrate transport and metabolism].	0
NC_018028.1\|WP_014819387.1\|1128520_1129129_-\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	3.09896e-68
NC_018028.1\|WP_162836508.1\|1129213_1130110_+\|ArgP/LysG-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|235144	PRK03635, PRK03635, ArgP/LysG family DNA-binding transcriptional regulator.	2.88971e-148
NC_018028.1\|WP_014819396.1\|1138786_1139011_+\|DUF2188-domain-containing-protein	gnl\|CDD\|378323	pfam09954, DUF2188, Uncharacterized protein conserved in bacteria (DUF2188). This domain, found in various hypothetical bacterial proteins, has no known function.	6.36464e-06
NC_018028.1\|WP_014819401.1\|1143972_1145754_-\|glyoxylate-carboligase	gnl\|CDD\|183066	PRK11269, PRK11269, glyoxylate carboligase; Provisional.	0
NC_018028.1\|WP_014819402.1\|1145863_1146772_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.89e-88
NC_018028.1\|WP_014819384.1\|1124378_1125062_-\|spermidine-synthase	gnl\|CDD\|223498	COG0421, SpeE, Spermidine synthase [Amino acid transport and metabolism].	3.05493e-25
NC_018028.1\|WP_014819392.1\|1133952_1135149_+\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	3.00941e-53
NC_018028.1\|WP_014819393.1\|1135152_1136355_-\|nicotinate-phosphoribosyltransferase	gnl\|CDD\|235406	PRK05321, PRK05321, nicotinate phosphoribosyltransferase; Provisional.	0
NC_018028.1\|WP_014819399.1\|1142092_1142983_-\|2-hydroxy-3-oxopropionate-reductase	gnl\|CDD\|185019	PRK15059, PRK15059, 2-hydroxy-3-oxopropionate reductase.	7.58323e-126
NC_018028.1\|WP_014819385.1\|1125193_1127254_-\|GGDEF-and-EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	9.98064e-113
NC_018028.1\|WP_014819397.1\|1139046_1140462_-\|pyruvate-kinase	gnl\|CDD\|180487	PRK06247, PRK06247, pyruvate kinase; Provisional.	0
NC_018028.1\|WP_014819395.1\|1137334_1138513_-\|NO-inducible-flavohemoprotein	gnl\|CDD\|237337	PRK13289, PRK13289, NO-inducible flavohemoprotein.	0
NC_018028.1\|WP_014819400.1\|1143011_1143794_-\|hydroxypyruvate-isomerase	gnl\|CDD\|226149	COG3622, Hfi, Hydroxypyruvate isomerase [Carbohydrate transport and metabolism].	6.5716e-153

>NC_018028.1|WP_014819393.1|1135152_1136355_-|nicotinate-phosphoribosyltransferase
MNSSAFSERIVQSLLDTDFYKLTMMQAVLHHYPNAEVEWAFRSRSGEDLTPYLDEIRQQIEALAELQMTTEELAYLERIPYMQPDFIRFLGLFRFDLRYLQVSIEDGELVMHLRGPWLHVILFEVPLLAIVSEVRNRARYPAVTLGQARDRLDEKLHWLRSQASSDELASFTLADFGTRRRFSFAVQAMVVDRLQCDFPGRFAGTSNVHLARTRNVKPMGTMAHEWIMAHQQLGPRLIDSQVAALDCWVREYRGALGIALTDCITMDAFLRDFDLYFAKLFDGLRHDSGDPLLWAEKAIAHYQRLGIDPKTRQLIFSDGLDLARALELHRALIGRSNPSFGIGTGLTCDIPGVEPTNMVIKMTACNGQPVAKISDSPGKTMCRDEAFVSYMRHVFGLANG
>NC_018028.1|WP_014819392.1|1133952_1135149_+|GGDEF-domain-containing-protein
MPSILDLLRSRLSSLLPSELKPSELRHLLSPRRHPLLLCQRRATLIVNRVRLFAFLFAVLTPLWSLIDLMVFEPRLWAALAGFRMMACLAFTCLLLFYRPSGNLLDAYRAIAILFAIPTIFYIASHTLLGSYQLAQFSAVVGAGYAFLPFVLMAGLTIFPLTLVENLVLSSLLLLAQALAGYLSWATLNWPSFAGAFWLLILIAGVASLASMSQLAFMFALVRQAIRDPLTGVFSRGSGEEILRLQWDSAQRKDGPLALAFIDLDHFKSINDNHGHESGDQVLREAARRLVATLRGSDSLLRWGGEEFLLIMPETDMQQAHMALERIIGQGLGVRPDGAPLTASIGLAERRCDQVADYRDLLELADKRMYCAKTSGRNRLCAMEPEAVQPPRAFAVGG
>NC_018028.1|WP_014819391.1|1131701_1133612_-|autotransporter-domain-containing-esterase
MQSALKLLAAAVLLTCATDAAIADDGPFSQFVVFGDSLSDAGNFPDLQSPTLGGNPTGGLRFTNRTGPTYGAGEYIGEVGTQRLASMLGLQSLPSTPLLPAVLTGNPDGTNYAVGGYRTDQILDSITLDSTVSAGGSTRTRPGYLVENPRVDSNALYYLNGGGNDIFQLGTNPVTMADAAGNLVAGVAALQAAGARYIIVSDLPDVGTTPLGFITGQAATFNFLSDQFNTELASQLQAQGGNYVLVNNRLLLAEVRADLAAFGFDPNVAQTAVCFDASGGTCLPDPTYSLGGTAPDPSRLLFNDAVHPTTAVHQISADYLYSIISAPWEVSLLPEMGRSALRAHLQQLDNELSARRGDWQAVGAWRTFVQGGYNRPEYDGYGGGDGSGLSLSLGVTQRLSETWLAGVSLGLAENSLELGRNDSEYDMRSYLATAFARYEHQRLFADFSLSAGYLDYHDLKRTFALGISERTEKGDTEGTLWGAAAKAGFNLMQPGDQLQFGPFVGASYQKVEVDGYSEQGERSTALSYDDQELDSLRLSLGLFGDYALSERTRLFGEVAREVEREDEDRRDLRMSLNSVSGNSFELPGAVPTGDQTRFSVGLTHRLTPGLALRANYHYRGNDNRDHGVGLSLAWDL
>NC_018028.1|WP_014819390.1|1130740_1131646_+|hypothetical-protein
MRNDAHDELDNIPSLTAGRDRVEPYPAPDLEPIRRTTDEPVDDGRSRQKRRPASTAGKVSTAPLWVMVLALLLSLGALGWWSYQKIAMLEMQLVATQESFARISEDAAGRLQDISGKVVATESNVTTESEAVKLRIKQLEQQAIDLERKQQAFATEQQSLTGKQGNQDRRMDEQGKRLEQLGADLQAQQGSTATLAESVKALGSEQASLKTTLDEQGKLAGRVDSLSKDIAALKQSGNQSQAISRLEQDILVLRSELDNRPAPAPNAINTAEFDSFRAQVTRTINSMQGQIANLQGQLDGR
>NC_018028.1|WP_014819389.1|1130114_1130381_-|hypothetical-protein
MELNKAVIDCMRSLRRRLRDEQQLDIHLDQPDAVTAMLAGCMNSNDELTRELGRQLAVFSDRLPAPPPPRAASSGATVRIYRGQRILA
>NC_018028.1|WP_162836508.1|1129213_1130110_+|ArgP/LysG-family-DNA-binding-transcriptional-regulator
MLMFDYKLLAALAAVVEQAGFERAAQALGLSQSAISQRIKLLEARVGQPVLLRDTPPRPTELGQRLLNHVQQVRLLERDLQGQVPALDENRLPERLRIALNADSLATWWAGAVASFCAEHRVLLDHVVEDQAVGLKRMRAGEVAACVCAAERPLAGARSQFLGAMRYRALASPVFVSRHFQRPAAAADLARVPAVVFGPDDQLQHRYMAAVGGGEAFVHHLCPSSEGFVRLLQSGLGWGLVPELQVRGELARGELVDVLSGPPIDVPLYWHHWRNGGQLLDELTRHLVRCASDWLLVD
>NC_018028.1|WP_014819387.1|1128520_1129129_-|amino-acid-transporter
MNAIWQSYINGLLVAAGLIMAIGAQNAFVLAQSLRREHHLPVAALCILCDVLLVSVGVFGLAAVLADNPLLLEITRWGGVAFLLWYGTLALRRAFKPQSLRSADAQPRPLRAVLLAALAVTLLNPHVYLDTVVLIGSLGAQQPEPGAYTLGAASASTLWFMTLALGGAWLAPWLARPLTWRLIDLGVAAMMFAIAAQLAFAS
>NC_018028.1|WP_014819386.1|1127538_1128120_-|superoxide-dismutase
MAFELPPLPYEKNALEPHMSAETLEFHHDKHHAAYVTNLNNLIPGTEFEGKDLESIIKTSSGGIFNNAAQVWNHTFFWNCLAPNAGGQPTGALADAINASFGSFDKFKEEFTKTAIGTFGSGWAWLVKKSDGSLGLASTIGAGNPMTAGDKPLLTCDVWEHAYYIDYRNARPKFVEAFWNLVNWEFVAKNFAG
>NC_018028.1|WP_014819385.1|1125193_1127254_-|GGDEF-and-EAL-domain-containing-protein
MKLEMRNSLSRKLLRVVLLSALAVGLVLSCAQIIFGAYKTRQLIEADAQRILRMTRDPSTQAIYSLDREMGAQVMEGLFQHESIRMASIGHPDEGMLALKIRPPIDLPTRWLTDPILHRDRQFSIPLIGKPPYNEYYGELRITLDTAKYGQEFINDSIVIFIVGILRALTLGFVLFLIYQWLLTRPLTKLIEHLARINPDRPGEHKLPMIRGHERNELGLWVETANGLLASIEHNMHLRQEAESSLYRMTQYDSLTGLPNRQQLQSQLDHILDEARRMQRRVAVLCLGLDDFKGVNEQYSYQAGDCLLKALADRLRGSAGRLGALARLGGDQFVLVLSGIEQPYEAAELAQALLDDLETPIEFDGDPIRLRATIGITLYPEDGDNTEKLLQKAEQTMTLAKSRSRNRYQFYVASIDSEMRARRELEKDLSEALKRNEFHLVYQPQVDYRQNRITGVEALIRWKHPQGKLVPPDLFIPLAEQNGSIIEIGKWVLDQACSQLRQWHAEGYTGLRVAVNLSTVQLRHPQLPQMIGELLQKHQLPAETLELEVTETGLMEDIDAAAHNLHSLRRSGALIAIDDFGTGYSSLSYLKSLPLDKIKIDKSFVQDIGQDEGATIVRAVIQLGKSLGMTVIAEGVETPEQEAYLIAEGCQEGQGYYYSKPLPARDLDLLLRQSTPFDRAVNSELR
>NC_018028.1|WP_014819384.1|1124378_1125062_-|spermidine-synthase
MKRFVLLDTAAIPTGGALCLFEYGDDFVIKIQGGNGNQLMNTRTHGSEDALAEIPCKRIAARSQARVLIGGLGMGFTLASALRHLGPDAEVLVAELVPGVIEWNRGALGEKSGNPLRDARARVLNQDVAELLRDQAQGFDAIMLDVDNGPEGLTQKSNSWLYSADGLNACARALRPSGILAVWSASADRAFSDKLAKAGFKAEEVQVFAHGNRGTRHTIWIAEKRKR
>NC_018028.1|WP_014819394.1|1137049_1137283_-|hypothetical-protein
MLYHSASPQRLMGAANALMVAGILLLLLGISGAYLFDRHLAMGSIIAAHALVILGPTALKIGYVMRLLAERKTKLAA
>NC_018028.1|WP_014819395.1|1137334_1138513_-|NO-inducible-flavohemoprotein
MLCAEQTALIKATVPLLESGGEALTTHFYNLLLSEHPEVRPLFNQAHQASGEQPRALANGVLMYAKHIDRLDALGPLVAQIINKHVALQVLPEHYPLVGSCLLRAIREVLGDEIATDAVIDAWGAAYQQLANILIGQEENLYQTKAEADGGWRGARRFRIARKTVESAEITSFHLQPEDGGALMDFLPGQYIGLRLEVDGQEVRRNYSLSAASNGSEYRISVKREPGGVASNALHAMPEGAVLELFAPAGEFTLEPGDKPLVLISGGVGITPTLAMLEQALASARPVHFIHCARNAGVHAFRRSVDALAERHAQLKRFYCYEEHDGADAAPDAVGRLTEQQLGRWLPEDRDVDAYFLGPKPFMAAVRRQLKSLGVPEQQTRYEFFGPASALD
>NC_018028.1|WP_014819396.1|1138786_1139011_+|DUF2188-domain-containing-protein
MEIYHITHEDDRWVLREEGDQRALLEAGNRQDILDETRDYMKLRTALVNVHGDDGSIEEEHRYPQEQNPLETRG
>NC_018028.1|WP_014819397.1|1139046_1140462_-|pyruvate-kinase
MTPDKKVKILATLGPTTRSVDDVRAMVQAGVNLFRLNFSHGEHADHAERFAWIREVERELNRPIGILMDLQGPKLRVGRFADGKVRLDRDQAFRLDLDPTPGDNRRVNLPHPEIIAALEPGMQLLIDDGRLCLTVTARHSDAIDTRVVAGGELSDRKGVNVPEAVLELSPLTEKDRRDLTFGLELGVDWVALSFVQRPQDIHEARKLIGERAFLMAKIEKPSAVQHLREIARLSDAIMVARGDLGVEVPPENVPRIQKNIVRICRQLGRPVVVATQMLESMRFAPAPTRAEVTDVANAVAEGADAVMLSAETASGDYPLEAVSMMSKIIRQVEGGPDFQAQLDVHRPNAEATLPDAISCAIRRISGILPIAVLVNYTESGRSSLRASRERPATPILSLTPSTATARKLTVAWGVYSVVDAPMRDMEQVSSHALELARAQGMAGSGDTVLITAGVPLGQPGTTNTLRIEVLD
>NC_018028.1|WP_014819398.1|1140494_1141766_-|glycerate-kinase
MPIDPQALLRQLFDSAIEAAHPRHVLADHLPEDRSGRAIVIGAGKAAAAMAEAIEKVWEGELSGLVVTRYEHHADCRRIEVVEAAHPVPDDAGERVARRVLELVSNLEESDRVIFLLSGGGSSLLALPAEGISLADKQAINKALLRSGAHIGEMNCVRKHLSAIKGGRLARACWPASVYTYAISDVPGDEATVIASGPTVADPTTSAEALAILERYHIEVPANVLAWLEDPRSETLKPGDPMLSRSHFQLIATPQQSLDAAAEVARSAGITPLILGDLEGEAREVAKVHAGIARQVVLHGQPIAVPCVILSGGETTVTVRGNGRGGRNAEFLLALTESLQGLPDVYALAGDTDGIDGSEDNAGALMAPDSFARAEAKGLRAADALADNDGYGYFAALDSLIVTGPTRTNVNDFRAILILPPSA
>NC_018028.1|WP_014819399.1|1142092_1142983_-|2-hydroxy-3-oxopropionate-reductase
MAKIGFIGTGIMGKPMASNLQNAGHQIFLSEHHDKAPADLVQAGAIARATPQEVAQEAEFIIVMVPDTPQVEDVLFRDQGIAAGVGPGKVVIDMSSISPSATKQFAEKIKASGAEYLDAPVSGGEVGAKAGSLSIMVGGSEAAFERALPLFQAMGKNITRVGENGDGQTAKVANQIIVALNIQAVAEALLFAAKNGADPAKVREALMGGFAGSKILEVHGERMIKGTFDPGFRISLHQKDLNLALAGARELGLNLPNTANAQQVFSTCAAIGGSGWDHSALIKGLEHMANFSIRKE
>NC_018028.1|WP_014819400.1|1143011_1143794_-|hydroxypyruvate-isomerase
MPRFAANLSMLFTEMDFLDRFAAAAEAGFTGVEYLFPYDYPAEEIKARLDANQLTQVLFNLPAGDWASGERGITILPERVEEFRAGVDQAIAYAKVLGNTQVNCLAGIAPRGADLGQLEITFIENLRYAAQKLEEAGIRLVMEMINTRDIPRFFLNNTSQAQEIRGKVGHPNLFLQYDIYHMQIMEGDLARTIENNLAAINHIQLADNPGRNEPGTGEINYHFLFEHLDRIGYQGWVGCEYKPATSTAEGLAWLKTHNAI
>NC_018028.1|WP_014819401.1|1143972_1145754_-|glyoxylate-carboligase
MARMRAIDAAVAVLRKEGIDTAFGIPGAAINPLYSALRADGSIRHILARHVEGASHMAEGYTRAKPGNIGVCIGTSGPAGTDMITGLYSASADSIPILCITGQAPRAKLHKEDFQAVDIESIAKPVTKWAVTVREPALVPRVFQQAFHVMRSGRPGPVLIDLPFDVQMGEIEFDIDTYEPLAVYKPAATRKQIEKAIDMLCAAERPLIVAGGGIYNAAAETLLVEFAETVGVPVIPTLMGWGSIPDDHPLMAGMCGLQTSHRYGNATMLESDFVLGIGNRWANRHTGSVETYTKGRTFVHVDIEPTQIGRVFAPDYGIVSDARAALELFVEVAKERKAADRLPDRRAWAADCLERKRTMLRKTNFDSVPMKPQRVYQCMNNAFGKDTCYVSTIGLSQIAAAQFLHVYQPRHWINCGQAGPLGWTIPAALGVVAADPARKVVALSGDYDFQFMIEELAVGAQFKLPYIHILVNNAYLGLIRQSQRGFEMDYCVQLGFENINADQSGMEGYGVDHVAVVEGLGCKALRVFKQEDLRPAIEQAQAWMAEHQVPVVIEVILERVTNIAMGTEIDAINEFEALAAGREDAPTAVGLLD
>NC_018028.1|WP_014819402.1|1145863_1146772_+|LysR-family-transcriptional-regulator
MDRYTTLRSFVLVADCGSFAAAAHKENVTPVVMGRRLDALERHLGVKLMHRSTRGLSLTDLGEQYLERARGLLKDFDEVDASISHDRTSVRGHLVVSAPAAFGRRHIGPHAPAFQARYPDLQLSFNFTDSVVDLVRHGYDMGIRIGEVTDPNYVAVRLFPNRRVVCGSPEYFARHGTPTALEELTQHNCLAFNLQGGQQRGWTFLRDGRQVAIRVAGNLDCNDGELLFDWVKQGLGIGWRSTWEIQAELKRGELVTVLDEYALPAYDIQAVYPQQRYLPAKVRFFIDYLKDIYNAPGYWEVR
>NC_018028.1|WP_014819403.1|1146777_1147188_-|hydroxyisourate-hydrolase
MKALRSIAAGLMLSGLSGLTLAAGNPLSVHVLNLENGLPSPDVRVTLEQRQGDAWKSLNSGETNAQGRITALYPEGKALEKGTYRVTFMTGDWFATHKASTFFPEVPVIFEADGSVEHYHIPLLLSPYGFSTYRGN

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Crispr_ID: NC_018028_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018028_2

1495380-1495480

Orphan

Consensus_repeat	Method
TGTGTGTTGGGTGTGTTGGGTTGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_018028_2

>merge|NC_018028|2|1495380-1495480|CRISPRCasFinder
TGTGTGTTGGGTGTGTTGGGTTGTGTTGGGTTGGGTTTGCGAACCCAGCACAGCGAGAGGCCAGCAACGGCGGGGCTTTGCGTGGTGTGTGTTGGGTGTGT

>NC_018028|2|2|1495380-1495480|CRISPRCasFinder
TGTGTGTTGGGTGTGTTGGGTTGTG	TTGGGTTGGGTTTGCGAACCCAGCACAGCGAGAGGCCAGCAACGGCGGGGC
TTTGCGTGGTGTGTGTTGGGTGTGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_018028.1\|WP_148273145.1\|1491160_1491646_+\|hypothetical-protein	unknown	unknown	unknown
NC_018028.1\|WP_014819655.1\|1488142_1488418_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377029
NC_018028.1\|WP_014819656.1\|1488429_1489131_-\|hypothetical-protein	unknown	unknown	unknown
NC_018028.1\|WP_051502660.1\|1491852_1492401_+\|hypothetical-protein	unknown	unknown	unknown
NC_018028.1\|WP_014819671.1\|1500013_1501324_+\|phage-portal-protein	unknown	unknown	gnl\|CDD\|377413
NC_018028.1\|WP_014819661.1\|1491638_1491860_+\|TraR/DksA-C4-type-zinc-finger-protein	unknown	unknown	gnl\|CDD\|222775
NC_018028.1\|WP_014819669.1\|1497775_1498303_+\|P27-family-phage-terminase-small-subunit	unknown	unknown	gnl\|CDD\|377461
NC_018028.1\|WP_051502661.1\|1497257_1497647_+\|HNH-endonuclease	unknown	unknown	unknown
NC_018028.1\|WP_014819666.1\|1496558_1496924_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374892
NC_018028.1\|WP_014819667.1\|1496916_1497261_+\|phage-holin-family-protein	unknown	unknown	gnl\|CDD\|368449
NC_018028.1\|WP_014819672.1\|1501327_1502203_+\|Clp-protease-ClpP	unknown	unknown	gnl\|CDD\|132927
NC_018028.1\|WP_041754261.1\|1489738_1490491_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224885
NC_018028.1\|WP_014819664.1\|1492665_1495368_+\|PriCT-2-domain-containing-protein	unknown	unknown	gnl\|CDD\|226990
NC_018028.1\|WP_014819674.1\|1503491_1503854_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237855
NC_018028.1\|WP_014819657.1\|1489127_1489463_-\|hypothetical-protein	unknown	unknown	unknown
NC_018028.1\|WP_014819670.1\|1498286_1500014_+\|terminase-large-subunit	unknown	unknown	gnl\|CDD\|226974
NC_018028.1\|WP_014819673.1\|1502215_1503430_+\|phage-major-capsid-protein	unknown	unknown	gnl\|CDD\|273690
NC_018028.1\|WP_148273146.1\|1495693_1496281_+\|hypothetical-protein	unknown	unknown	unknown
NC_018028.1\|WP_014819658.1\|1489459_1489654_-\|hypothetical-protein	unknown	unknown	unknown
NC_018028.1\|WP_014819663.1\|1492400_1492673_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_018028.1\|WP_014819655.1\|1488142_1488418_-\|hypothetical-protein	gnl\|CDD\|377029	pfam03374, ANT, Phage antirepressor protein KilAC domain. This domain was called the KilAC domain by Iyer and colleagues.	0.00808513
NC_018028.1\|WP_014819666.1\|1496558_1496924_+\|hypothetical-protein	gnl\|CDD\|374892	pfam16931, Phage_holin_8, Putative phage holin.	3.27538e-09
NC_018028.1\|WP_014819661.1\|1491638_1491860_+\|TraR/DksA-C4-type-zinc-finger-protein	gnl\|CDD\|222775	PHA00080, PHA00080, DksA-like zinc finger domain containing protein.	1.13149e-12
NC_018028.1\|WP_014819669.1\|1497775_1498303_+\|P27-family-phage-terminase-small-subunit	gnl\|CDD\|377461	pfam05119, Terminase_4, Phage terminase, small subunit.	1.8382e-15
NC_018028.1\|WP_014819670.1\|1498286_1500014_+\|terminase-large-subunit	gnl\|CDD\|226974	COG4626, COG4626, Phage terminase-like protein, large subunit [General function prediction only].	1.32147e-116
NC_018028.1\|WP_014819673.1\|1502215_1503430_+\|phage-major-capsid-protein	gnl\|CDD\|273690	TIGR01554, prophage_Lp3_protein_18, phage major capsid protein, HK97 family. This model family represents the major capsid protein component of the heads (capsids) of bacteriophage HK97, phi-105, P27, and related phage. This model represents one of several analogous families lacking detectable sequence similarity. The gene encoding this component is typically located in an operon encoding the small and large terminase subunits, the portal protein and the prohead or maturation protease. [Mobile and extrachromosomal element functions, Prophage functions].	1.127e-49
NC_018028.1\|WP_014819667.1\|1496916_1497261_+\|phage-holin-family-protein	gnl\|CDD\|368449	pfam05449, Phage_holin_3_7, Putative 3TM holin, Phage_holin_3. This is a family of putative proteobacterial phage three-transmembrane-domain holins.	6.95344e-13
NC_018028.1\|WP_014819672.1\|1501327_1502203_+\|Clp-protease-ClpP	gnl\|CDD\|132927	cd07016, S14_ClpP_1, Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease. Clp protease (caseinolytic protease; ClpP; Peptidase S14) is a highly conserved serine protease present throughout in bacteria and eukaryota, but seems to be absent in archaea, mollicutes and some fungi. This subfamily only contains bacterial sequences. Clp proteases are involved in a number of cellular processes such as degradation of misfolded proteins, regulation of short-lived proteins and housekeeping removal of dysfunctional proteins. They are also implicated in the control of cell growth, targeting DNA-binding protein from starved cells. ClpP has also been linked to the tight regulation of virulence genes in the pathogens Listeria monocytogenes and Salmonella typhimurium. This enzyme belong to the family of ATP-dependent proteases; the functional Clp protease is comprised of two components: a proteolytic component and one of several regulatory ATPase components, both of which are required for effective levels of protease activity in the presence of ATP, although the proteolytic subunit alone does possess some catalytic activity. Active site consists of the triad Ser, His and Asp; some members have lost all of these active site residues and are therefore inactive, while others may have one or two large insertions. ClpP seems to prefer hydrophobic or non-polar residues at P1 or P1' positions in its substrate. The protease exists as a tetradecamer made up of two heptameric rings stacked back-to-back such that the catalytic triad of each subunit is located at the interface between three monomers, thus making oligomerization essential for function.	8.46416e-66
NC_018028.1\|WP_041754261.1\|1489738_1490491_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|224885	COG1974, LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms].	2.46152e-22
NC_018028.1\|WP_014819664.1\|1492665_1495368_+\|PriCT-2-domain-containing-protein	gnl\|CDD\|226990	COG4643, COG4643, Uncharacterized protein conserved in bacteria [Function unknown].	2.77912e-29
NC_018028.1\|WP_014819674.1\|1503491_1503854_+\|hypothetical-protein	gnl\|CDD\|237855	PRK14900, valS, valyl-tRNA synthetase; Provisional.	3.99383e-08
NC_018028.1\|WP_014819671.1\|1500013_1501324_+\|phage-portal-protein	gnl\|CDD\|377413	pfam04860, Phage_portal, Phage portal protein. Bacteriophage portal proteins form a dodecamer and is located at a five-fold vertex of the viral capsid. The portal complex forms a channel through which the viral DNA is packaged into the capsid, and exits during infection. The portal protein is though to rotate during DNA packaging. Portal proteins from different phage show little sequence homology, so this family does not represent all portal proteins.	1.64205e-101

>NC_018028.1|WP_014819664.1|1492665_1495368_+|PriCT-2-domain-containing-protein
MSERVPLTLADLPELLQYIPAGDRDTWLQVGMGIKAEFGNNGFDAWDTWSAAADSYSTADAKTVWRSFRKAGTGMGTVIKLAKDEGWRPRREPITAEEKRRLNAEAEARRAVRQAEIEADEARAQVMRETVAAACELIWTKHCKPQGESPYLERKRVGAFGVGYFHYTVVLAIDDERQRCDVWVGSETREFFAAMPKPRPDSLSFLMFKAGSIAIPLRDAAGKLWSLQAINEQGTKLFPKYGRKAGCRHVLGELEGATVIGEAEGYATAASVHMAKGWPVAMALDSGNMPAVARDLVAQCPDALLVVAGDDDPTKPGNPGRKKADAAAGEVGGIAAFPTQPAEGEAGQDWNDVHVAWGLNAVAQQLDAAVAAGKPSPTPSADEAAAPAGSSDTGGQGVGFTSEQILRRFALVEGTTQVWDQDKKAVMKKTAFEALVSKPLAKAWADDVAKKLIGADTVRELEQARRMAGKKASALGMTPIERYVYIDGTKDVWDREKKRRIPEGAVKMALGDAYALWLNSAERRTVDVDHIVFDPTMTKDPAVYINTFEGLPLEPVRDDAACENLRWLISFLCNHEDAPLQWLVKWLAYPLQHPGAKLDTAVLMHSVMEGSGKSLLFADTLGALYGPYAATVGQTQLESNFNAWQSRKLWAVFEEVVSRDQRYNQVGKIKHLITGKTVRMESKFINGWEEANHMNAVFLSNEILPWPISESDRRFLVMWPLETLPEERQRAIGAELANGGVAALYGWLLDVDLGDFNERTRPPHTDARQRLVALSRAGWQTFLNQWQHGELGHKLWGACLSTDLYALFLEWCQRNREHAMSQTKFSLFISSEVEKTRSIPWTEGANRRFGAFFFPSDPDSSLPPSMNAAALGQHVAGWRAKAKLAGWDVDGWDHLKGAAA
>NC_018028.1|WP_014819663.1|1492400_1492673_+|hypothetical-protein
MHEFQILTDAQEAHRLASKALSEKMRQIFREGATEVVVDGAGRRMPVEVRFICGGSEAGYLRVMPINGKRTRRSMRSVHWTQIEREADDV
>NC_018028.1|WP_051502660.1|1491852_1492401_+|hypothetical-protein
MVDQVIAEHAVPAGYVLMPKTLTAENGAKAALIGEFTIRHEVTCSGCAYDEADDDCEVCGGEIEYTERVTVPWDVIKDIYAAAVKACGTGAAPDAPRPPAATEDSARLEFMLERHRTVVVELLPSRGDCGKYAIYVEEGFMRDKQYPSVGFTVTGALRADDEAFKKAKFDAIDAAIAAQGAN
>NC_018028.1|WP_014819661.1|1491638_1491860_+|TraR/DksA-C4-type-zinc-finger-protein
MDEHLIERAQREQDEELQRIIASRVQYQGESLTECEGCGGEIPQARRDAVKGCRMCTDCQAFADKMSAGVRRG
>NC_018028.1|WP_148273145.1|1491160_1491646_+|hypothetical-protein
MRATMLEHGPLTTLEAAIDRDAREAIRGGHTAVCAILEEPYGPFQKRLSCSYPDHHLHADDVERVIALVQGPAVLAWFEQVYGVVSFKPTPVPATRDALKALGKLLQAEGEFVGSLHDGAADNVWEPHEVETLRGHANRMISEILGIVAGAEQAMGEQRHG
>NC_018028.1|WP_041754261.1|1489738_1490491_-|XRE-family-transcriptional-regulator
MVQQPEEMRSAFVIRLKKAAEYANTPAWGLGARLASITNRTPKAASKWLNGESMPSRASMQAIAEAFKVRLEWLQYGIGLMIDGSETSYPRAIAPARQIRENVNVWPVKPPHREMKEYPLISWIAAGCWAESCDNYQPGDGQEFIASTENAGDHGYWLEVKGDSMVPPDGFAFNDGTRILVRPEGFDLISGKLYVAKLIETGETTFKQYVRDAGIEYLKPLNPTYRTIVIDENVRIIGRVIDARPPKSLL
>NC_018028.1|WP_014819658.1|1489459_1489654_-|hypothetical-protein
MDTAQHSSTRCPVFLHPAAASNPFTVRRIERETGLTAHVTLRTAQLKRNTLPAFEDFGPFGGAA
>NC_018028.1|WP_014819657.1|1489127_1489463_-|hypothetical-protein
MNSRIEVIALQIMALCLRITAAGRYTASCEYDGDNYCITCRVRTPSPTKARASATAEEHRARVLLTEYIYIEAFTHSLDLDEAKAKTVCADLEALIEKLIGYTRAESEVPA
>NC_018028.1|WP_014819656.1|1488429_1489131_-|hypothetical-protein
MSTFSLTRGSEAALGMLASQAGCETLLLTQPARELRAELSIEPFTSDSGDQLLAVLFMREQRHSMTLQRDDGANVQHLADWIVAVANGTLDTAEAVPQRADPSDLAAATAAFHAAAHELNAHAEPAPAQDEQYPPCDFCGVIPDHHPWHGSGMFKGFDSPHIHACNDCRHLLPSRPAHTEQQPEQISLEPALHKLCAEWERQKRLFPELNRGGWMDLAISEARRALSATSPKA
>NC_018028.1|WP_014819655.1|1488142_1488418_-|hypothetical-protein
MNRTLDQAAAVLGIGPRKMRARMRELGLLNHAGELISTERGRGRLFVDTRSRWNPAIKSYTHYGVVMATEAGIAWLAEQLDITVTKKDAAA
>NC_018028.1|WP_148273146.1|1495693_1496281_+|hypothetical-protein
MIEAMEVLLQAWGREVVNPALDVAIASPLGRMGDDTPGGVGGHRCLSLVECAVAISRASQAVSMALDGMAKDAALGLGSRGRVLQRLAHVRYCQGPQAVAVAAQCARLGISMRTYRAQVDELHAELQAEWPVALARLQLAERGTDAHAAAVKRARAARDVARENARAERKRLADRKAAARAVKAAAELRKVGAAG
>NC_018028.1|WP_014819666.1|1496558_1496924_+|hypothetical-protein
MAEPTSTTAGVVVAGAAGAGLAGFMAGVNGDAAVGALLGALVYVTTTHDLPIWKRLLFFLVSAVMGYQFAPAIVEADFWGFRPFAYPGPAAFGAAVLVVTLALAAIRRRGVPSISDGGADG
>NC_018028.1|WP_014819667.1|1496916_1497261_+|phage-holin-family-protein
MVSALLTQVTFLICLVLFVRLFTYRRGAARFRRGVSCLAMLVMGCAGAAVIYILTGELRVPAMAWPLVVLLAVFAWAVWQSGGNLAGAFRPGGWDGVERRQQERRAALSTVRRR
>NC_018028.1|WP_051502661.1|1497257_1497647_+|HNH-endonuclease
MSNHAPRPCCHPGCGVLVGTGSYCPTHQAQSDERRAAMRQQTHKRYNRQRDDSDKFYSTVAWRRFRDHYLIMHPLCVDCEEEGDIEPAVVVDHIKPFKERPDLGLDEDNVRGLCRRHDNKRRHDRTGRD
>NC_018028.1|WP_014819669.1|1497775_1498303_+|P27-family-phage-terminase-small-subunit
MDHAYPKVIEGGLGSAEESTTQTIAAEAPTPPVKLNAKEKKLWEHVTSALEEYGLIHRTDGLLMTVICKTFCNWVAQEEFLEKLKRDNGSYYVKTPNGYEQPHQAYYVARDYKRELLKWLPEAALTIPSFQKLKADQTTPQGDLFGDDPIEQFRQRKARMGLRAIPGGKTDGGED
>NC_018028.1|WP_014819670.1|1498286_1500014_+|terminase-large-subunit
MVEKTERTFDWDLYGRQVMAGEIPVCKWTRLAVERHYRDLQDGHKRGLWFSEDHAQHALEFFLFLRHSKGEWAGHQFVPSLWQQFWVALAFGWMRADGTRRFRRVWEEVPRKNGKSTKLSGVGLYLFFADGEGGAEVYTAATKMDQAKITHDEAVRMVGSSPGLRRKIADRRGELFIRGKADTFKPLGRDSKSLDGLNPHGAILDEVHAHPDAGIIDVIRSGTGARRQWLMWMITTAGVNLRGPGFELHGYAEKVLEGVFDDDEFLAIIYTVDDPDKWQEPNEWIKANPNLGVSVYEQGLRDACNSAVRLPSEQPEFKTKRLNIWLSGGAKWLPLADWRRCERKGLRLEDFRGKRCWIGLDLAERRDIAALCLVFREEGKYFAFWRFYQNEHQANLPENKHYLKWAAAGYLHITPGNATDFDVIGDAIAGQRDPNDPDKVIKPGFLQEFAVEEVDYDPKFAPYFAKKLMEKGVPMVEIGQNPTTFTAPIIETENLVLTGELVHEENPVMDWMISNAKKLTSKFNGLSQIAKDRESEKIDGVLALLMAVARATASEFEEPPGDPDGFYSNPIMVGV
>NC_018028.1|WP_014819671.1|1500013_1501324_+|phage-portal-protein
MANEKKPGRVKSVLLNWLGVPIGLTSGTFWEEWFGQSTSGKSVTVDAALQLSTVWACVRLLSETVSTLPLKLYRRQPDGSRTVATDHPLYRVLCISPNAEMTPGRFMLMIVASLALRGNAFVEKKLIGSRIVALVPLLPQHMRVKRQSNGRLEYIYNENGTERPIPEKSLMHIRGFGLDGVCGIMPVKAGREVLGAAMSADEAAARVFAQGLQASGVLTNENGALKPEQREQLRQSLAAFAGSKNAGKLMVLEAGLKYQGITMNPEAAQMLETRAFQIEEICRWFRVPPFMVGHTDKQSSWASSVEGQNLQFLTNTLRPLLDNIEQEIIRCLIGEAEAETVYAEFSVEGLLRADLDARREWYASALQNGWMNRNTVARLENQPLIPGGDVYTVQSNLMPLDQLGQQRTDSEQARAALQNWLNTAPASNPPAAQAGD
>NC_018028.1|WP_014819672.1|1501327_1502203_+|Clp-protease-ClpP
MTIRNLPVAPEARPCAGVSFDLRPQALERWNPSILAAADDEENTISVLDPIGYDCWTGEGVTAKRITGILKGMAGADVTVNINSPGGDMFEGLAIYNVFREYKGHVTVRVLGMAASAASIIAMAGDTIQVARSGFLMIHNCWAGAVGNRHDFRDFADTLEPFDEAMADIYATRTGDDIAAMQKLMDGETWINGSAAVEQGFADSLLPSDSVKESTKARSGSQYAAHKLDVILAKQGMPRSERRSLLQQLKAGTPSAASHGTRDAADTPADLAEPIADLQRALARFTAAATQ
>NC_018028.1|WP_014819673.1|1502215_1503430_+|phage-major-capsid-protein
MTDSSTAELLKKVSAELERASSDFSKKAESALDEAKKAGNLSAETKATVDELALKFNSLTDAEKQLKAQLGELEQEFARIPAQASASQRTTVGAEVIKSEALKEFAKSVQGNRRISVPVNAALLSVDVAEGVVEPQRLPGIDIMPKQRLFIRDLIATGRTTSPAIFWVQQTGFTNAAAVVAENTAKPYSNISFDTKITPVTTIAHMFKASKQILDDFAQLQSTVDAEMRYGLKYVEEQEILFGDGTGAHLDGIVPQASAFSAAFAPADMTQIDELRLAMLQAQLARLPASGHVLHFTDWAKIELTKDSLGRYIIGNPLGVVGPTLWGLPVVSTEIAAFQGKFLTGAFQTGAQIFDREDANVVISTENADDFEKNMISIRCEERLALAVKRPEAFIFGTFTVPAP
>NC_018028.1|WP_014819674.1|1503491_1503854_+|hypothetical-protein
MKLKALKPLYIGGAVVDPGKTFDTTDVHGKQLVKKDYAEVIDAKAEKAAADKAAADQAAAEKAAADKAAADQAAAEKAAADKAAADHAAAEKAAADKAAADKAAADQATADKSTAGKAAK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_018028_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018028_3

1896148-1896255

Orphan

Consensus_repeat	Method
TGCCCCTCACCCTGACCCTCTCCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_018028_3

>merge|NC_018028|3|1896148-1896255|CRISPRCasFinder
TGCCCCTCACCCTGACCCTCTCCCCGGAGGGGCGAGGGTACGGTCGGGTGTCTGGTCCGACCGCTTGTGTTTGTTTGGAGGGTTGCCCCTCACCCTAACCCTCTCCCC

>NC_018028|3|3|1896148-1896255|CRISPRCasFinder
TGCCCCTCACCCTGACCCTCTCCCC	GGAGGGGCGAGGGTACGGTCGGGTGTCTGGTCCGACCGCTTGTGTTTGTTTGGAGGGT
TGCCCCTCACCCTAACCCTCTCCCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018028.1\|WP_014820004.1\|1909348_1910059_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NC_018028.1\|WP_014819998.1\|1900832_1902449_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|236724
NC_018028.1\|WP_014819997.1\|1900101_1900821_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_018028.1\|WP_041754314.1\|1908937_1909339_-\|hypothetical-protein	unknown	unknown	unknown
NC_018028.1\|WP_014819996.1\|1896513_1899393_-\|ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|235966
NC_018028.1\|WP_014819993.1\|1892861_1893545_-\|RelA/SpoT-domain-containing-protein	unknown	unknown	gnl\|CDD\|143389
NC_018028.1\|WP_014819999.1\|1902474_1903146_-\|DUF4197-domain-containing-protein	unknown	unknown	gnl\|CDD\|379394
NC_018028.1\|WP_041754725.1\|1906688_1908920_+\|catalase/peroxidase-HPI	unknown	unknown	gnl\|CDD\|237891
NC_018028.1\|WP_148273154.1\|1891404_1892184_-\|hypothetical-protein	unknown	unknown	unknown
NC_018028.1\|WP_014820001.1\|1903770_1906269_-\|glycerol-3-phosphate-1-O-acyltransferase-PlsB	unknown	unknown	gnl\|CDD\|235325
NC_018028.1\|WP_014819988.1\|1888015_1888708_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|173926
NC_018028.1\|WP_014819990.1\|1889246_1889972_-\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224103
NC_018028.1\|WP_014819989.1\|1888814_1889165_-\|TfoX/Sxy-family-protein	unknown	unknown	gnl\|CDD\|225612
NC_018028.1\|WP_014819991.1\|1890089_1890983_+\|transcriptional-regulator-GcvA	unknown	unknown	gnl\|CDD\|182990
NC_018028.1\|WP_014819986.1\|1886113_1887247_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340968
NC_018028.1\|WP_014819994.1\|1893546_1894656_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379293
NC_018028.1\|WP_014820005.1\|1910128_1910911_-\|class-D-beta-lactamase	unknown	unknown	gnl\|CDD\|225322
NC_018028.1\|WP_014819995.1\|1894769_1896017_-\|ribonucleotide-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|235968
NC_018028.1\|WP_187289382.1\|1887387_1887873_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_018028.1\|WP_014820000.1\|1903336_1903765_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|236715

Protein	Function_ID	Function_description	E-value
NC_018028.1\|WP_014820004.1\|1909348_1910059_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	5.18761e-16
NC_018028.1\|WP_014819998.1\|1900832_1902449_+\|HAMP-domain-containing-protein	gnl\|CDD\|236724	PRK10604, PRK10604, sensor protein RstB; Provisional.	6.43785e-92
NC_018028.1\|WP_014819997.1\|1900101_1900821_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	5.64258e-85
NC_018028.1\|WP_014819993.1\|1892861_1893545_-\|RelA/SpoT-domain-containing-protein	gnl\|CDD\|143389	cd05399, NT_Rel-Spo_like, Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases. This family includes the catalytic domains of Escherichia coli ppGpp synthetase (RelA), ppGpp synthetase/hydrolase (SpoT), and related proteins. RelA synthesizes (p)ppGpp in response to amino-acid starvation and in association with ribosomes. (p)ppGpp triggers the bacterial stringent response. SpoT catalyzes (p)ppGpp synthesis under carbon limitation in a ribosome-independent manner. It also catalyzes (p)ppGpp degradation. Gram-negative bacteria have two enzymes involved in (p)ppGpp metabolism while most Gram-positive organisms have a single Rel-Spo enzyme (Rel), which both synthesizes and degrades (p)ppGpp. The Arabidopsis thaliana Rel-Spo proteins, At-RSH1,-2, and-3 appear to regulate a rapid (p)ppGpp-mediated response to pathogens and other stresses. This catalytic domain is found in association with an N-terminal HD domain and a C-terminal metal dependent phosphohydrolase domain (TGS). Some Rel-Spo proteins also have a C-terminal regulatory ACT domain. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition.Two of the three catalytic carboxylates are found in Rel-Spo enzymes, with the second carboxylate of the DXD motif missing. Evidence supports a single-cation synthetase mechanism.	1.15061e-20
NC_018028.1\|WP_014819999.1\|1902474_1903146_-\|DUF4197-domain-containing-protein	gnl\|CDD\|379394	pfam13852, DUF4197, Protein of unknown function (DUF4197). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 228 and 249 amino acids in length.	2.22235e-90
NC_018028.1\|WP_041754725.1\|1906688_1908920_+\|catalase/peroxidase-HPI	gnl\|CDD\|237891	PRK15061, PRK15061, catalase/peroxidase.	0
NC_018028.1\|WP_014819996.1\|1896513_1899393_-\|ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|235966	PRK07207, PRK07207, ribonucleoside-diphosphate reductase subunit alpha.	0
NC_018028.1\|WP_014820001.1\|1903770_1906269_-\|glycerol-3-phosphate-1-O-acyltransferase-PlsB	gnl\|CDD\|235325	PRK04974, PRK04974, glycerol-3-phosphate 1-O-acyltransferase PlsB.	0
NC_018028.1\|WP_014819988.1\|1888015_1888708_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|173926	cd04301, NAT_SF, N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate. NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.	1.60523e-05
NC_018028.1\|WP_014819990.1\|1889246_1889972_-\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|224103	COG1182, AcpD, Acyl carrier protein phosphodiesterase [Lipid metabolism].	7.66687e-52
NC_018028.1\|WP_014819989.1\|1888814_1889165_-\|TfoX/Sxy-family-protein	gnl\|CDD\|225612	COG3070, TfoX, Regulator of competence-specific genes [Transcription].	2.0378e-14
NC_018028.1\|WP_014819991.1\|1890089_1890983_+\|transcriptional-regulator-GcvA	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	7.12646e-98
NC_018028.1\|WP_014819986.1\|1886113_1887247_-\|MFS-transporter	gnl\|CDD\|340968	cd17410, MFS_CynX_like, Cyanate transport protein CynX and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of Escherichia coli cyanate transport protein CynX and similar proteins. CynX is part of an active transport system that transports exogenous cyanate into E. coli cells. The gene encoding CynX is part of the cyn operon that also includes cynS, encoding cynase, which catalyzes the reaction of cyanate with bicarbonate to give ammonia and carbon dioxide, and cynT, which encodes a carbonic anhydrase. The CynX-like subfamily belongs to the 2-nitroimidazole and cyanate transporters like (NIMT/CynX-like) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.69521e-88
NC_018028.1\|WP_014819994.1\|1893546_1894656_-\|AAA-family-ATPase	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	2.62715e-28
NC_018028.1\|WP_014820005.1\|1910128_1910911_-\|class-D-beta-lactamase	gnl\|CDD\|225322	COG2602, COG2602, Beta-lactamase class D [Defense mechanisms].	1.53365e-65
NC_018028.1\|WP_014819995.1\|1894769_1896017_-\|ribonucleotide-diphosphate-reductase-subunit-beta	gnl\|CDD\|235968	PRK07209, PRK07209, ribonucleotide-diphosphate reductase subunit beta; Validated.	0
NC_018028.1\|WP_187289382.1\|1887387_1887873_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.01384e-19
NC_018028.1\|WP_014820000.1\|1903336_1903765_+\|N-acetyltransferase	gnl\|CDD\|236715	PRK10562, PRK10562, putative acetyltransferase; Provisional.	1.04758e-43

>NC_018028.1|WP_014819995.1|1894769_1896017_-|ribonucleotide-diphosphate-reductase-subunit-beta
MLSWDEFNEEDTTTAAPAPAAAQPASQTAAKLDNDAAGSVEEARAVAASDSDAIARAKRALDDLDIQEGLNELEGESARVRVDEKRMINARADLNQLVPFKYDWAWQKYLDGCANHWMPQEVNMNADIALWKSKDGLSEDERRIVKRNLGFFSTADSLVANNLVLATYRLITNPECRQYILRQAFEEAIHTHAYQYCIESLGMDEGEIFNMYHEIPSVAKKASWGLKYTRSISDPTFQTGTPETDKQFLRNLIAYYCVLEGIFFYCGFTQILSMGRRNKMTGTAEQFQYILRDESMHLNFGIDMINQIKIENPHLWDADMKDEATQMILQGTQLEIEYARDTMPRGVLGMNAAMMEDYLKFIANRRLTQIGLKEEYPGTTNPFPWMSEIMDLKKEKNFFETRVIEYQTGGALSWD
>NC_018028.1|WP_014819994.1|1893546_1894656_-|AAA-family-ATPase
MKVISVFNNKGGVGKTTLTYHLAHALAESGKKILMIDADPQCNLTIYSLDQDTVHDIWEAEDEFIDQGFESTKAKVGSIRFSVLNSRTRSLHYLLKPTEEGTGELEYLPPPRQITNNLDIIPGRLTLHLYEEKIASRWTDAYRGEPLAIRTITKIRSLAEQYSKEYNYDYVIVDTSPSLGSLNKVIISTVDGFFVPASPDLFSLYGIRNIGKALTSWKDEFEIIYKLISLEKRHNFPERFVTFLGYTIYNAKKYSGYNNKWDLAHAHLNYAHQIPATIRANIAPDLREHLSDELLSSPIGATLVMHSHNTFPSMAQHYHNPMWKVPGLPNIEPEHLNTLRGASQRYLETKDSYIAFGQDLLSRIDLLGK
>NC_018028.1|WP_014819993.1|1892861_1893545_-|RelA/SpoT-domain-containing-protein
MPTNEIIDAAIEAYQRDKHLFEKFLNGVVDSFRLEPRLNTYGNPLIYTIKSRLKDPSHLREKISRKWSDADPITAENLFARVTDLAGVRVLHLYQDQFPEIHNHIQKQVEAGDWFLREPPVAYSWDPEASGFFESMGLIAKTKDSYYTSIHYVVAPKKDSPIYCEIQVRTLFEEIWGEIDHTINYPTPTQSNSCKEQLRVLSKLVSTGTRLADSIFRTQKELNSTKQ
>NC_018028.1|WP_148273154.1|1891404_1892184_-|hypothetical-protein
MNGKTLYKTTQEIVEDTEDLLLNTKLKFLPARWIHRQALAPIKLLFLGSAEVFRPLSKWAFMAIASLLIGTLFIQSTEMPIEHAQAVLLFLMYAPIILVMFAVPSTYTFSDLKPHQIVGVSRIITSKLIDSENKLKLFEKNLEAIENRTTERVRSFKWLIGTFWAASLFFLTQINSFTLRSKDFDLNKTLQDNMSFLVTAIMITIISLWITTSYKRATEAIFKSIKYSICEIKLHLSDPEHNKDTLDTPQKKQETPTNN
>NC_018028.1|WP_014819991.1|1890089_1890983_+|transcriptional-regulator-GcvA
MAHRRLPSLSALRAFEAAARHESAKQAAEELSVTATAISHQIRSLEESLGVALFLRKPRKLELTDPGRELQQTLETAFDSISATVERLSAKPCRQAITLSTTPAIAVRWLVPWVCLLRDSHPDIDLRFHTSHEPVALDGVTADIAIRYGDGRWPGLVAEKLFDNTFVPVCSPHLGLRDIAELPKHPLIHFRAQAALSAPIHWASWQKLANVPGLDVSAGLVFSDETHAISAAIGAQGVALMSRQLIEDELREGRLVQPFGPEMEGKPFHLVYPESRRDDPTVRAVRGWVMAVPGGFV
>NC_018028.1|WP_014819990.1|1889246_1889972_-|NAD(P)H-dependent-oxidoreductase
MTHLLHLDASARPGLAGKDEHGSHSRNLTHRFVSQWAARRAQDGIVYRDIGQNPPSFISHDWIASSFTPEERREPWMRDTLAESDQLVDELIAADVLVIGTPLYNFGMPAALKAWIDQIVRPGRTVEVDESKLPDPYVPLLADRPRHAVILSARGGIGFGPGGEMAHMNHLEPNLVTALNFIGITRIHQIAIEGQETGGEVLAASVTEALRQVDALVTELQASLDTPPLHARTRQAEFDQV
>NC_018028.1|WP_014819989.1|1888814_1889165_-|TfoX/Sxy-family-protein
MASDRDFVLYVAEQMGLGSRLTYRKMFGEYALYLDEKVVAFVCDNSLFIKPSAAAETLAPDLPQAPPYPGAKNYPVADELLDDADELRRLVIETARLMPAPAPRKPRKRKPDAAAT
>NC_018028.1|WP_014819988.1|1888015_1888708_-|GNAT-family-N-acetyltransferase
MFTLTHLNTPPPESLKSQVLQMVVDYLGDISPVSLQPSNPLYQLYQYVVGFEVHRYLDSMDGAQAGKPELIMALDADDPTVLLGFALYLPFVDDPEACALVYLAVDADHRRQGIGRGMVEAMVTRYPHAEVACVAGKVPYFSALGFQPLASRGPQVVMNTRNEASNGAVAVQDLEPIFQSKEVRQIYSYLVQQNGRKAMSEAEKQRDRLLDQLARQAQDLVQQSSVRRLH
>NC_018028.1|WP_187289382.1|1887387_1887873_+|MarR-family-transcriptional-regulator
MIDRAQLAVEQWQQQRPDLDTLPMRLIGRLGEAVQVLNRDVLQPFFDEHRLHYGEFDVLATLRRAGVPHALSPTALYEAAMISSGGMTNRLDRLERAGLIERKPNPEDRRGTLVALTEAGFNLIDGLMTAHVENEKTALATLSRDEQEQLDRLLGKWLAGR
>NC_018028.1|WP_014819986.1|1886113_1887247_-|MFS-transporter
MLVLLVGLNLRPILAAIGPLLDEIQAATGLGSAGAGALTTLPIAAMGFCALGGAMLQAKLGERRGVALGLTLVALASALRWGSPNVAGLILTAALGGVGIALVQALIPAYIHRCHPQRTSALMGLYTTGIMGGAALAAASAAPLAERFGWANGLALWAIPAVLTLSIWWSLARPPIATERTASRPLPLKSPHAWRLLLFFGIGTAAYTLVLAWLPPYYTGLGWSAADSGLLLGGISLAEVGAGLLLSALIGRIRQRRPLVLGVLAVVLAGLLCLTLAPLALAIPTAILLGVGIGALFPLSLILAMDHARDSADAGSLLGFVQGGGYLIASLAPLGAGLLRDRLASLADAWLLMAVGIMLLMGLALQLTAPSQEAQPL
>NC_018028.1|WP_014819996.1|1896513_1899393_-|ribonucleoside-diphosphate-reductase-subunit-alpha
MQNPSTRENPLSADAPDLAATAPGQLRVIKRNGTVVPYTDDKITVAITKAFLAVEGGNAAASSRIHDTVARLTEQVTATFRRRMPSGGTIHIEEIQDQVELALMRAGEQKVARDYVIYREARSQERKSAAANDIAQPHPSIRVTRADGSQQPLDMGRLQTIITEACEGLAEVDGALIERETLKNLYDGVAEKDVNTALVMTARTLVEREPNYSQVTARLLMDTLRAEALGFLGVAESATHHEMADLYAKALPAYIEKGVEFELLDSKLKSYDLAKLGAALNHERDQQFTYLGLQTLYDRYFIHKNDVRFELPQIFFMRVAMGLAIEEEQKEARAIEFYNLLSSFDYMASTPTLFNAGTLRPQLSSCYLTTVPDDLGGIYDAIRDNALLSKFAGGLGNDWTPVRALGAYIKGTNGKSQGVVPFLKVVNDTAVAVNQGGKRKGAVCAYLETWHLDIEEFLELRKNTGDDRRRTHDMNTANWIPDLFMKRVFDDVPWTLFSPSDVPDLHDLTGRAFEERYEYYEELTKYGKIKLFKTLPAKDLWRKMLSMLFETGHPWLTFKDPCNLRSPQQHVGVVHSSNLCTEITLNTNKDEIAVCNLGSINLVNHIKDGKLDAAKLERTVRTAVRMLDNVIDINYYSVPQAQNANFKHRPVGLGIMGFQDALYLQHIAYGSDAAIDFADKSMEAISYFAIQASCDLADERGAYSSFQGSLWSQGILPLDSQQILIEARGQKYIDVDLTESLDWAPIRERVKKGIRNSNIMAIAPTATISNIVGVSQSIEPTYQNLYVKSNLSGEFTVINPYLVHDLKARGLWDPVMVNDLKYYDGSVQQIERIPQDLKDMYATAFEVETKWIVDAASRRQKWIDQAQSLNLYIAGASGKKLDVTYRMAWYRGLKTTYYLRALAATSTEKSTINTGKLNAVSSGGSEAANSASAAPAAEPQPAPVPLACSIDNPDCEACQ
>NC_018028.1|WP_014819997.1|1900101_1900821_+|response-regulator-transcription-factor
MEQDTWRILIVEDDRRLAELTQEYLQSDGGFVVSIESDGACAAARIIEERPDLVVLDLMLPGEDGLSICRQVRDRYDGPILMLTARADDLDQVMGLETGADDYVCKPVRPRLLLARIRALLRRREAPEAPANAKRLQFGPLVIDSALREAWLREQQIELTGAEFDLLWLLTSNPGRILSREEIFAELRGIEYDGQDRSIDVRISRIRPKIGDDPDHPRLIKTVRGKGYLFVSEAAVAMV
>NC_018028.1|WP_014819998.1|1900832_1902449_+|HAMP-domain-containing-protein
MNSIFLRIYGGMLGVLVLVALLGAGGLHLLNQYRADDHRERLASGTFRLMAHNMSSMTPIERRQAANLWGRLLGIPLRVRTLDDVSLESRLEARLLRGQVLVEQIRPQSTTVFSLVSAQDRLVLTGEVEQLSEQLARATIYLLIDELIRYPEAEQPRRLAELKQARGFGFDLELLTRDSANLDDDQRRRLDEGDTVMALARGGDAVRVFAAIAGTGWIMQLGPLYQMNPYPPQLLILIGLLGLSLIGLTVYLLVRQLEQRLSVLEGAATRIAAGNLETRVPDVGTDSVGRLAAAFNGMARHLQRLLAVQREMVSAVAHELRTPVARLRFGLEMSAEAQTDEARRKYLEGMDGDIDDLDALVDEMLVYSRLERGSPTLHFQQVDLDALVDQVIGELAPLRADVSVRRGECTTAADGSCWAEAEPQYLRRALSNLINNAMRHAESRVQVSFTIDGQTVRLEVDDDGPGVPEADWEKVFTPFLRLDDSRTRASGGHGLGLSIVRRIIYWHGGRSQLGHSDLGGARFSLVWPRRRADRAAAG
>NC_018028.1|WP_014819999.1|1902474_1903146_-|DUF4197-domain-containing-protein
MLRITTLVAGLALSASAFALSLSDLTQSDASAGLKDALSQGAKVAVQQLGRPGGFSSDPDVRIELPGNIGKASRMLKMLGMGAQVEQLENSMNLAAEKAVPEAQQLLLDAVRKMTVQDAKAILAGGDDSATQYLNQSSREQIRAKFLPIVKQATDQVGLAQQYNAVAAKVPAGMNGSYANIESYVTEQALDGLFTVIAEQEASIRKNPAAAATSLAKKVFGLL
>NC_018028.1|WP_014820000.1|1903336_1903765_+|N-acetyltransferase
MIRPFRPDDLEPVLAIWLAASIRAHDFIAPAFWASKLDDMRDIYLPAAQIWVDEREGEVLGFVALVGDVLAAIFVAPSAQGGGIGSALIEQAKTVRERLELTVYSANAASVAFYRRHGFAVISEQLDPHTGHPELAMAWQRD
>NC_018028.1|WP_014820001.1|1903770_1906269_-|glycerol-3-phosphate-1-O-acyltransferase-PlsB
MTRSPVRRLIFSVLRRVLYFWVRSETINQSAFTLKLDRSKPVFYVLQQPSLSDLAVLDVECSKAGLPRPVADVVVGDHVEPAAFFFLNPATSWFGRRTRLVAPPTLVRLVGALEHNAVENAQIIPVSVFWGQSPNRETSAWKLLFADSWAVTGRLRKLLSILVLGRKTRVQFSAPIQLNELIALNKGHERTLRMIHRMLRVHFRNQKTAVIGPDLSHRRNLVKGLVHAPQVRQAIRDEAERENISIERAEARALRYGNEVASDYAYTAVRFLEVVLSWFWNKIYDGIRVNHIEPLQDAVRGYEVIYVPCHRSHIDYLLLSYLLFRNGLTPPHIAAGINLNMPVIGSLLRRGGAFFMRRSFKGNPLYTSVFNEYLHNLFTRGFPVEYFVEGGRSRTGRMLQPKTGMLALTLRSYVRSSRLPILFVPVYIGYERVLEGRTYLGELRGAAKKKESIFDIFKVIGALKQRFGQVWVNFGEPLKLNEFLDQEQPGWRQQTYAPDYRPEWLNDATNRLAERIAQRLNEAAAVNPVNLVALAMLSTSRQALDQQSLARILDLYQALLRAVPYSPHTTLPEGDGNALIAYVKSLDLLAEQKDALGNILYLDEQNAVLMTYYRNNVMHIFALPALLASFFQSSSRISREQIQRFTEALYPYLRAELFMRWEVEELEAVVDQWLAAFVERGLLKVDGNHYVRPAPSSRQFVLLTLLARVVVQTLQRFYMATSLLLNSGQHSLSAEELENLCTVMAQRLSILHGLNAPEFFDKALFRHFIQSMQEQGVVSPDENGRLGYHEKLAELAEGAAKRVLPAEIRLSIRQVALERHHDDSDSTPPQAA
>NC_018028.1|WP_041754725.1|1906688_1908920_+|catalase/peroxidase-HPI
MNEESGEKAGGVCPFGHGAGAPRKRPGNRDWWPEALSLTSLNQHSPRSNPYGGDFDYAAAFNSLDLDAVIADLHALMTDSQDWWPADFGHYGGLFIRMAWHSAGTYRITDGRGGAGGGQQRFAPLNSWPDNAALDKARRLLWPIKQKYGRKLSWADLFVLTGNVALESMGFKTFGFGGGRADTWEPEELFWGPEGTWLGDERYSGERQLHPGLGAVQMGLIYVNPEGPNGKPDPKAAAIDIRETFARMAMNDYETVALIAGGHTFGKTHGAGDPSLMGPEPEGAVIEDQGLGWRSRYKSGIGADAITSGLEVIWSQTPTKWSNYFFENLFNFEWELTKSPAGAHQWEAKDAAEIMPDPFDPNKKRKPTMLTTDLSLRFDPEYEKISRHFLENPDEFADAFAKAWFKLTHRDMGPIGRYLGPLVPKEQLIWQDPIPERDHPVIDAADIAALKQQLLGMGFSVSELVSVAWASAATYRGSDKRGGANGARIRFAPQKDWEINNPPLLEKVLHKLGEIQNDFNGSATGGKKVSMADLIVLAGCAAIEKAAQDGGVNVTVPFTPGRMDAEEEWTDAQSFEALRPVADGFRNYYHESHFMAPEEALVDKAHLLRLSAPEMTVLVGGMRVLGTNADGGSEGVFTNRVGTLTNDFFVNLLDMKNEWTATEHKNRFQGLDRKTRQPTWTATRVDLIFGAQSELRAQAEVYGMADGNEKFVQDFVKAWDKVMNVDRLDIGKPADNFSQKLSA
>NC_018028.1|WP_041754314.1|1908937_1909339_-|hypothetical-protein
MAAASDRPSIKRSVLRSFLLATLAGAAIWSLSPSMTGHVEPWDAGGLYYTAALALGGCLCGSIAPKPLWPLYAGCVAGQTLYLLGWLPTGPLLPVGLVFVLLCSLVFLVGAYVGSRARTRWQARKQQPPRGGA
>NC_018028.1|WP_014820004.1|1909348_1910059_-|class-I-SAM-dependent-methyltransferase
MRNDEIKAIFDQQATSYDERWARTAPIREALHFLLEAVFADLPADARILCVGAGTGEEIAYLARRFPRWSFTAVEPSGAMLEVCRNKAIEGGYAERCQFHEGYLQSLPEQDAFDAATCFLVSQFILEPGARAEFFRAIASRLRPGARLASSDLASDIASAEYTALLETWMNMMTVAGIPAAGVEQMRTAYSRDVAVLPRERVAAIIESGGFTDPVLFYQAGLIHAWYSTRSTVDAQ
>NC_018028.1|WP_014820005.1|1910128_1910911_-|class-D-beta-lactamase
MPQLFLALLFLGFSGFAHAEDADIARLFDEAGVDGTLVIESAETGQRYVHNEARAKQPFTAASTFKVLNTLIALEEGAIAGADEIIPWDNTRYEIEDWNRDQTLKSAFQVSCVWCYQWLARRVGAADYPPHIRQAHYGQLREPFNGTEFWLDGSLTISAEQQIELLKRVTARSLPYRTSSYDTLKTVMLTEAAKDYRLYAKTGWAARSTPGTGWYIGYVETGENTWLFALNLDTRTVRDLPLRQQIALNALRAKGILPAD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1283810 : 1330032

Ralstonia_phage(25.0%)

protease,coat,transposase,tRNA,integrase

attL 1316750:1316768|attR 1330787:1330805

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014819520.1\|1283810_1285226_+\|protease	DegQ family serine endoprotease	A0A1B1IT49	uncultured_Mediterranean_phage	3.8e-27	31.6
WP_003293585.1\|1285415_1287215_+	elongation factor 4	E4ZFJ7	Streptococcus_phage	4.3e-20	26.7
WP_003293584.1\|1287216_1288071_+	signal peptidase I	NA	NA	NA	NA
WP_014819521.1\|1288163_1288541_+	DUF4845 domain-containing protein	NA	NA	NA	NA
WP_014819522.1\|1288537_1289227_+	ribonuclease III	A0A1C9C5A7	Heterosigma_akashiwo_virus	2.7e-23	38.3
WP_014819523.1\|1289219_1290131_+	GTPase Era	NA	NA	NA	NA
WP_014819524.1\|1290179_1290869_+	DNA repair protein RecO	NA	NA	NA	NA
WP_014819525.1\|1290861_1291608_+	pyridoxine 5'-phosphate synthase	NA	NA	NA	NA
WP_014819526.1\|1291741_1291948_-	DUF2905 domain-containing protein	NA	NA	NA	NA
WP_014819527.1\|1291932_1292886_-	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	1.2e-08	29.3
WP_014819528.1\|1293018_1293306_+	hypothetical protein	NA	NA	NA	NA
WP_014819529.1\|1293321_1294284_-\|tRNA	tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB	NA	NA	NA	NA
WP_014819530.1\|1294280_1295024_-	carboxy-S-adenosyl-L-methionine synthase CmoA	NA	NA	NA	NA
WP_014819531.1\|1295097_1295499_-\|protease	protease inhibitor I42 family protein	NA	NA	NA	NA
WP_014819532.1\|1295644_1298032_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	1.1e-135	38.3
WP_014819533.1\|1298157_1298913_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014819534.1\|1299176_1302338_+	bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA	NA	NA	NA	NA
WP_014819535.1\|1302583_1304068_+	sodium/proline symporter PutP	NA	NA	NA	NA
WP_014819536.1\|1304212_1304437_-	DUF3203 family protein	NA	NA	NA	NA
WP_014819537.1\|1304664_1306686_+	TonB-dependent receptor	NA	NA	NA	NA
WP_014819538.1\|1306901_1308386_+	sodium/proline symporter PutP	NA	NA	NA	NA
WP_014819539.1\|1308511_1309327_-	DUF1206 domain-containing protein	NA	NA	NA	NA
WP_041754198.1\|1309566_1309746_+	hypothetical protein	NA	NA	NA	NA
WP_014819540.1\|1309745_1309895_+	hypothetical protein	NA	NA	NA	NA
WP_148273139.1\|1309963_1310329_+	hypothetical protein	NA	NA	NA	NA
WP_014819542.1\|1310556_1311537_-\|transposase	IS5-like element ISPa16 family transposase	A0A077K814	Ralstonia_phage	2.9e-95	58.0
WP_014819543.1\|1311732_1312575_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014819544.1\|1312778_1313633_+	CoA transferase subunit A	NA	NA	NA	NA
WP_014819545.1\|1313632_1314415_+	CoA-transferase subunit beta	NA	NA	NA	NA
WP_014819546.1\|1314411_1315617_+	3-oxoadipyl-CoA thiolase	NA	NA	NA	NA
WP_014819547.1\|1315848_1316670_+	3-oxoadipate enol-lactonase	NA	NA	NA	NA
1316750:1316768	attL	NA	NA	NA	NA
WP_014819548.1\|1316888_1317671_-	DUF2726 domain-containing protein	NA	NA	NA	NA
WP_014819549.1\|1317847_1318687_-	hypothetical protein	S5W9H2	Leptospira_phage	3.1e-05	40.6
WP_014819550.1\|1318726_1319482_-	hypothetical protein	NA	NA	NA	NA
WP_148273141.1\|1319516_1320230_-	hypothetical protein	NA	NA	NA	NA
WP_014819553.1\|1320713_1320929_+	hypothetical protein	NA	NA	NA	NA
WP_148273142.1\|1320925_1321075_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014819554.1\|1321071_1321245_+	Arc family DNA-binding protein	NA	NA	NA	NA
WP_080583051.1\|1321284_1321623_+	DUF5447 family protein	Q56VP7	Pseudomonas_phage	4.6e-16	45.3
WP_014819555.1\|1322434_1323415_-\|transposase	IS5-like element ISPst5 family transposase	A0A077K814	Ralstonia_phage	5.5e-94	57.0
WP_014819556.1\|1323500_1323860_+	hypothetical protein	NA	NA	NA	NA
WP_014819557.1\|1323875_1324055_+	hypothetical protein	NA	NA	NA	NA
WP_014819558.1\|1324051_1324267_+	hypothetical protein	NA	NA	NA	NA
WP_014819559.1\|1324277_1324487_+\|coat	phage coat protein	NA	NA	NA	NA
WP_041754657.1\|1325778_1326078_+	hypothetical protein	NA	NA	NA	NA
WP_014819561.1\|1326077_1326404_+	DUF2523 domain-containing protein	NA	NA	NA	NA
WP_014819562.1\|1326416_1327601_+	zonular occludens toxin	Q6UAZ2	Ralstonia_phage	1.3e-36	30.6
WP_014819563.1\|1327747_1329025_+	hypothetical protein	Q56VN8	Pseudomonas_phage	9.3e-134	56.3
WP_014819564.1\|1329006_1330032_+\|integrase	tyrosine-type recombinase/integrase	Q56VN7	Pseudomonas_phage	1.9e-89	50.0
1330787:1330805	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1419891 : 1466975

Micromonas_sp._RCC1109_virus(18.18%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_181063908.1\|1419891_1420197_-\|transposase	transposase	NA	NA	NA	NA
WP_011078028.1\|1424453_1425026_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	1.2e-59	100.0
WP_011078029.1\|1425251_1426910_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	5.6e-22	36.4
WP_011078030.1\|1427077_1428328_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	2.2e-47	46.5
WP_009397186.1\|1429486_1430917_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_003292104.1\|1431751_1432192_-	heme-binding protein	NA	NA	NA	NA
WP_014819620.1\|1432222_1432414_-	2-hydroxymuconate tautomerase	NA	NA	NA	NA
WP_014819621.1\|1432462_1433257_-	2-oxo-3-hexenedioate decarboxylase	NA	NA	NA	NA
WP_009397183.1\|1433253_1434294_-	4-hydroxy-2-oxovalerate aldolase	E5EQ69	Micromonas_sp._RCC1109_virus	2.4e-47	36.7
WP_003292099.1\|1434306_1435230_-	acetaldehyde dehydrogenase (acetylating)	E5EQ71	Micromonas_sp._RCC1109_virus	5.8e-37	37.4
WP_003292096.1\|1435244_1436030_-	2-oxopent-4-enoate hydratase	NA	NA	NA	NA
WP_014819622.1\|1436041_1436890_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_003292094.1\|1436900_1438361_-	2-hydroxymuconic semialdehyde dehydrogenase	NA	NA	NA	NA
WP_003292092.1\|1438395_1439319_-	catechol 2,3-dioxygenase	NA	NA	NA	NA
WP_003292091.1\|1439315_1439654_-	2Fe-2S iron-sulfur cluster binding domain-containing protein	NA	NA	NA	NA
WP_014819623.1\|1440096_1441410_-	salicylate 1-monooxygenase	NA	NA	NA	NA
WP_003292087.1\|1441565_1442468_+	HTH-type transcriptional activator NahR	NA	NA	NA	NA
WP_014819624.1\|1443141_1444122_+\|transposase	IS5-like element ISAch1 family transposase	A0A077K814	Ralstonia_phage	8.0e-93	57.9
WP_003292084.1\|1444121_1445540_+	FAD-dependent monooxygenase	NA	NA	NA	NA
WP_014819627.1\|1448088_1448709_-	LysE family translocator	NA	NA	NA	NA
WP_003292082.1\|1449225_1449453_+	hypothetical protein	NA	NA	NA	NA
WP_024162459.1\|1449483_1450476_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_003292079.1\|1450575_1452528_-	acetoacetate--CoA ligase	NA	NA	NA	NA
WP_003292078.1\|1452540_1453449_-	hydroxymethylglutaryl-CoA lyase	A0A1V0SKU2	Klosneuvirus	3.1e-43	38.7
WP_014819629.1\|1453697_1454987_-\|transposase	ISL3-like element ISPpu12 family transposase	A0A2D1GQC1	Lysinibacillus_phage	3.6e-85	40.4
WP_004863699.1\|1455008_1455521_-	signal peptidase II	NA	NA	NA	NA
WP_004364974.1\|1455524_1456421_-	cation transporter	NA	NA	NA	NA
WP_009403731.1\|1456516_1456924_+	Cd(II)/Pb(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_003292076.1\|1457031_1458093_+	alcohol dehydrogenase catalytic domain-containing protein	NA	NA	NA	NA
WP_003292074.1\|1458591_1459200_+	glutathione transferase GstA	NA	NA	NA	NA
WP_003292072.1\|1459463_1460141_+	type 1 glutamine amidotransferase domain-containing protein	NA	NA	NA	NA
WP_085989415.1\|1460239_1461193_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	6.2e-50	41.8
WP_080583088.1\|1461763_1462120_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	4.7e-19	40.5
WP_046154764.1\|1464563_1465919_-	outer membrane protein transport protein	NA	NA	NA	NA
WP_010466230.1\|1465994_1466975_+\|transposase	IS5-like element ISPre2 family transposase	A0A077K814	Ralstonia_phage	7.0e-97	59.0

DBSCAN-SWA_3

1476862 : 1518254

Pseudomonas_phage(48.28%)

protease,terminase,head,capsid,lysis,portal,integrase,tail,holin

attL 1478954:1478997|attR 1518420:1518463

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014819640.1\|1476862_1478716_-\|integrase	tyrosine-type recombinase/integrase	A0A0U1UNT3	Pseudomonas_phage	4.7e-102	50.2
1478954:1478997	attL	NA	NA	NA	NA
WP_014819641.1\|1479150_1480350_+\|integrase	integrase family protein	A0A248SL35	Klebsiella_phage	1.6e-39	31.8
WP_014819642.1\|1480346_1481087_+	hypothetical protein	NA	NA	NA	NA
WP_014819643.1\|1481083_1481287_-	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_014819644.1\|1481273_1481585_-	hypothetical protein	NA	NA	NA	NA
WP_014819645.1\|1481581_1481980_-	hypothetical protein	NA	NA	NA	NA
WP_014819646.1\|1481976_1483569_-	DNA cytosine methyltransferase	A0A1I9KFD6	Aeromonas_phage	3.0e-142	54.6
WP_014819647.1\|1483576_1484206_-	phosphohydrolase	H6VU98	Escherichia_phage	8.0e-22	41.6
WP_014819648.1\|1484202_1484889_-	3'-5' exoribonuclease	A0A1W6JP74	Morganella_phage	7.2e-32	45.7
WP_014819649.1\|1484885_1485371_-	hypothetical protein	NA	NA	NA	NA
WP_041754259.1\|1485426_1486209_-	hypothetical protein	A0A1B0YZY3	Pseudomonas_phage	1.2e-88	65.3
WP_014819651.1\|1486266_1487097_-	YfdQ family protein	I3PUY7	Vibrio_phage	3.7e-43	39.9
WP_014819652.1\|1487138_1487486_-	hypothetical protein	A0A2D1GMS3	Marinobacter_phage	2.0e-14	42.2
WP_014819653.1\|1487526_1487784_-	pyocin activator PrtN family protein	NA	NA	NA	NA
WP_014819654.1\|1487780_1488146_-	hypothetical protein	NA	NA	NA	NA
WP_014819655.1\|1488142_1488418_-	hypothetical protein	NA	NA	NA	NA
WP_014819656.1\|1488429_1489131_-	hypothetical protein	NA	NA	NA	NA
WP_014819657.1\|1489127_1489463_-	hypothetical protein	NA	NA	NA	NA
WP_014819658.1\|1489459_1489654_-	hypothetical protein	NA	NA	NA	NA
WP_041754261.1\|1489738_1490491_-	XRE family transcriptional regulator	A0A2H4J6J6	uncultured_Caudovirales_phage	2.0e-43	60.3
WP_148273145.1\|1491160_1491646_+	hypothetical protein	NA	NA	NA	NA
WP_014819661.1\|1491638_1491860_+	TraR/DksA C4-type zinc finger protein	H2BDI2	Pseudomonas_virus	1.5e-07	44.4
WP_051502660.1\|1491852_1492401_+	hypothetical protein	A0A192Y6F5	Salmonella_phage	7.0e-06	40.0
WP_014819663.1\|1492400_1492673_+	hypothetical protein	NA	NA	NA	NA
WP_014819664.1\|1492665_1495368_+	PriCT-2 domain-containing protein	A0A2H4JF22	uncultured_Caudovirales_phage	3.5e-239	75.8
WP_148273146.1\|1495693_1496281_+	hypothetical protein	NA	NA	NA	NA
WP_014819666.1\|1496558_1496924_+	hypothetical protein	NA	NA	NA	NA
WP_014819667.1\|1496916_1497261_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_051502661.1\|1497257_1497647_+	HNH endonuclease	NA	NA	NA	NA
WP_014819669.1\|1497775_1498303_+\|terminase	P27 family phage terminase small subunit	NA	NA	NA	NA
WP_014819670.1\|1498286_1500014_+\|terminase	terminase large subunit	G3EN96	Psychrobacter_phage	8.0e-88	36.0
WP_014819671.1\|1500013_1501324_+\|portal	phage portal protein	A0A0U4IJ43	Pseudomonas_phage	1.8e-177	72.5
WP_014819672.1\|1501327_1502203_+\|protease	Clp protease ClpP	A0A0U4B0J0	Pseudomonas_phage	6.6e-99	64.6
WP_014819673.1\|1502215_1503430_+\|capsid	phage major capsid protein	A0A0U4JIW8	Pseudomonas_phage	2.8e-180	82.5
WP_014819674.1\|1503491_1503854_+	hypothetical protein	NA	NA	NA	NA
WP_014819675.1\|1503869_1504196_+\|head,tail	phage gp6-like head-tail connector protein	A0A0U4JEH2	Pseudomonas_phage	1.7e-28	64.3
WP_014819676.1\|1504196_1504745_+	hypothetical protein	NA	NA	NA	NA
WP_014819677.1\|1504744_1505305_+	hypothetical protein	A0A0U4J906	Pseudomonas_phage	2.9e-47	52.3
WP_014819678.1\|1505301_1505736_+	hypothetical protein	A0A0U4IBQ1	Pseudomonas_phage	4.1e-41	58.7
WP_041754689.1\|1505768_1506551_+	hypothetical protein	A0A0U4ISK2	Pseudomonas_phage	4.0e-95	67.8
WP_014819680.1\|1506627_1507350_+	hypothetical protein	NA	NA	NA	NA
WP_014819681.1\|1507408_1507774_+	hypothetical protein	NA	NA	NA	NA
WP_051502662.1\|1507942_1510084_+	tape measure protein	A0A0U3TH20	Pseudomonas_phage	8.8e-137	44.5
WP_014819683.1\|1510094_1510592_+	hypothetical protein	A0A0U4IIK1	Pseudomonas_phage	1.2e-39	51.6
WP_014819684.1\|1510591_1512361_+	hypothetical protein	A0A1W6JTA3	Pseudomonas_phage	1.2e-147	49.3
WP_014819685.1\|1512360_1513203_+	hypothetical protein	NA	NA	NA	NA
WP_014819686.1\|1513211_1513643_+	hypothetical protein	NA	NA	NA	NA
WP_014819687.1\|1513632_1515303_+	hypothetical protein	NA	NA	NA	NA
WP_014819688.1\|1515318_1515777_+	hypothetical protein	A0A0U4B0K9	Pseudomonas_phage	4.5e-38	59.4
WP_014819689.1\|1515773_1516202_+	hypothetical protein	A0A2H4J973	uncultured_Caudovirales_phage	1.3e-26	50.0
WP_041754264.1\|1516246_1516720_+	hypothetical protein	A0A2H4JFP9	uncultured_Caudovirales_phage	1.1e-52	69.2
WP_014819691.1\|1516716_1517250_+\|lysis	lysis protein	A0A1B0VMJ3	Pseudomonas_phage	2.8e-15	38.1
WP_041754266.1\|1517235_1517550_-	hypothetical protein	A0A2H4JER5	uncultured_Caudovirales_phage	1.4e-11	41.8
WP_014819693.1\|1517552_1518254_-	SOS response-associated peptidase family protein	A0A2H4J5W2	uncultured_Caudovirales_phage	1.2e-58	50.4
1518420:1518463	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1664984 : 1734536

Staphylococcus_phage(12.5%)

protease,integrase,transposase,holin

attL 1712423:1712437|attR 1731371:1731385

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014819822.1\|1664984_1665410_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_014819823.1\|1665406_1666165_+	DUF3618 domain-containing protein	NA	NA	NA	NA
WP_003285663.1\|1667037_1667685_+	hypothetical protein	NA	NA	NA	NA
WP_014819824.1\|1667961_1670325_+	DEAD/DEAH box helicase family protein	NA	NA	NA	NA
WP_041754708.1\|1670734_1671697_+	HNH endonuclease	NA	NA	NA	NA
WP_014819826.1\|1671699_1673166_+	SAM-dependent DNA methyltransferase	J7I0U9	Acinetobacter_phage	7.4e-26	32.3
WP_011912641.1\|1673162_1674131_+	virulence RhuM family protein	NA	NA	NA	NA
WP_011912642.1\|1674127_1675711_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	6.3e-23	39.0
WP_014819827.1\|1675727_1676813_+	nuclease	NA	NA	NA	NA
WP_014819828.1\|1676859_1679205_+	anti-phage defense ZorAB system ZorA	NA	NA	NA	NA
WP_014819829.1\|1679204_1679969_+	OmpA family protein	NA	NA	NA	NA
WP_014819830.1\|1679965_1682224_+	hypothetical protein	NA	NA	NA	NA
WP_014819831.1\|1682223_1685262_+	DEAD/DEAH box helicase	A0A2L0WU59	Oxyplax_ochracea_nucleopolyhedrovirus	1.3e-21	22.6
WP_014819555.1\|1685421_1686402_+\|transposase	IS5-like element ISPst5 family transposase	A0A077K814	Ralstonia_phage	5.5e-94	57.0
WP_085983834.1\|1686783_1688006_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	1.4e-118	76.6
WP_014819833.1\|1688074_1689982_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	3.0e-43	33.6
WP_014819834.1\|1690080_1692210_-	TonB-dependent siderophore receptor	NA	NA	NA	NA
WP_014819835.1\|1692440_1693991_-	GGDEF domain-containing protein	G3MA91	Bacillus_virus	6.4e-12	29.7
WP_046154767.1\|1694398_1696249_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_014819837.1\|1696536_1698435_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_014819838.1\|1698466_1699450_-	lipid A deacylase LpxR family protein	NA	NA	NA	NA
WP_014819839.1\|1699527_1700592_-	hypothetical protein	NA	NA	NA	NA
WP_014819840.1\|1700595_1700844_-	acyl carrier protein	NA	NA	NA	NA
WP_014819841.1\|1700840_1702760_-	HAD family hydrolase	NA	NA	NA	NA
WP_014819842.1\|1702781_1704320_-	MBOAT family protein	A0A125RNP0	Pseudomonas_phage	3.3e-85	41.8
WP_014819843.1\|1704719_1704953_-	hypothetical protein	NA	NA	NA	NA
WP_014819844.1\|1705088_1705748_-	response regulator	W8CYM9	Bacillus_phage	3.7e-17	40.2
WP_014819845.1\|1705734_1709139_-	response regulator	Q8QKV7	Ectocarpus_siliculosus_virus	1.8e-35	29.0
WP_041754290.1\|1709483_1710725_+	urea ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014819847.1\|1710788_1711706_+	urea ABC transporter permease subunit UrtB	NA	NA	NA	NA
WP_014819848.1\|1711752_1712949_+	urea ABC transporter permease subunit UrtC	NA	NA	NA	NA
1712423:1712437	attL	NA	NA	NA	NA
WP_014819849.1\|1712945_1713698_+	urea ABC transporter ATP-binding protein UrtD	A0A2H4PQG7	Staphylococcus_phage	5.5e-17	27.4
WP_014819850.1\|1713841_1714531_+	urea ABC transporter ATP-binding subunit UrtE	G9BWD6	Planktothrix_phage	7.7e-18	29.8
WP_014819851.1\|1714814_1716044_+	acetamidase/formamidase family protein	A0A1V0S8X7	Catovirus	7.6e-133	57.1
WP_014819852.1\|1716122_1716470_+	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_014819853.1\|1716572_1717613_+	aliphatic amidase	NA	NA	NA	NA
WP_014819854.1\|1717879_1718917_+\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A1L2CUT6	Pectobacterium_phage	8.3e-32	31.8
WP_014819855.1\|1718987_1719863_+	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
WP_014819856.1\|1720017_1721133_+	glycosyltransferase family 1 protein	NA	NA	NA	NA
WP_014819857.1\|1721125_1721887_+	DUF2334 domain-containing protein	NA	NA	NA	NA
WP_014819858.1\|1721883_1722876_+	flippase-like domain-containing protein	NA	NA	NA	NA
WP_014819859.1\|1722962_1723154_+	CsbD family protein	NA	NA	NA	NA
WP_003285709.1\|1723233_1723557_-	ferredoxin family protein	NA	NA	NA	NA
WP_187289389.1\|1723678_1726246_-	DNA mismatch repair protein MutS	A0A1V0SJ67	Klosneuvirus	9.9e-26	22.7
WP_014819861.1\|1726308_1727550_-\|integrase	site-specific integrase	A0A1I9KF78	Aeromonas_phage	1.3e-63	38.3
WP_014819862.1\|1727516_1727714_-	hypothetical protein	NA	NA	NA	NA
WP_014819863.1\|1728277_1728463_-	hypothetical protein	NA	NA	NA	NA
WP_014819864.1\|1728522_1728927_-	hypothetical protein	NA	NA	NA	NA
WP_014819865.1\|1728961_1729426_-	hypothetical protein	NA	NA	NA	NA
WP_014819866.1\|1729949_1732421_+	toll/interleukin-1 receptor domain-containing protein	NA	NA	NA	NA
1731371:1731385	attR	NA	NA	NA	NA
WP_014819867.1\|1732576_1732780_-	hypothetical protein	NA	NA	NA	NA
WP_148273153.1\|1732939_1733128_+	hypothetical protein	NA	NA	NA	NA
WP_014819868.1\|1733165_1734536_-\|transposase	IS1182 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

2235449 : 2239573

uncultured_Caudovirales_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003284967.1\|2235449_2235776_-	YnfA family protein	A0A218MNG8	uncultured_virus	4.6e-29	61.9
WP_014820249.1\|2235786_2236281_-	cyclin-dependent kinase inhibitor 3 family protein	NA	NA	NA	NA
WP_014820250.1\|2236299_2237013_-	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	6.4e-108	80.6
WP_014820251.1\|2237032_2237503_-	arsenate reductase ArsC	A0A2H4J8A6	uncultured_Caudovirales_phage	7.8e-46	60.3
WP_014820252.1\|2237516_2237873_-	metalloregulator ArsR/SmtB family transcription factor	A0A2H4J145	uncultured_Caudovirales_phage	4.2e-36	63.2
WP_014820253.1\|2237883_2238297_-	arsenate reductase ArsC	A0A2H4J437	uncultured_Caudovirales_phage	3.2e-43	67.9
WP_014820254.1\|2238490_2239573_+	NAD(P)/FAD-dependent oxidoreductase	A0A2H4J2Q2	uncultured_Caudovirales_phage	1.9e-103	64.4

DBSCAN-SWA_6

2370645 : 2384540

uncultured_Caudovirales_phage(75.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014820361.1\|2370645_2371314_+	Bax inhibitor-1/YccA family protein	A0A2H4JFM9	uncultured_Caudovirales_phage	4.4e-87	77.1
WP_014820362.1\|2371413_2372682_-	MFS transporter	NA	NA	NA	NA
WP_014820363.1\|2372896_2373289_+	sulfurtransferase complex subunit TusD	A0A2H4JA39	uncultured_Caudovirales_phage	7.7e-47	71.3
WP_014820364.1\|2373288_2373648_+	sulfurtransferase complex subunit TusC	A0A2H4J8C0	uncultured_Caudovirales_phage	1.9e-31	59.2
WP_014820365.1\|2373647_2373950_+	sulfurtransferase complex subunit TusB	A0A2H4JG28	uncultured_Caudovirales_phage	3.1e-24	59.0
WP_014820366.1\|2373946_2374279_+	TusE/DsrC/DsvC family sulfur relay protein	A0A2H4J8B6	uncultured_Caudovirales_phage	4.5e-40	73.4
WP_014820367.1\|2374275_2375259_+	glycosyl transferase family protein	A0A2H4JBY5	uncultured_Caudovirales_phage	7.4e-147	77.1
WP_014820368.1\|2375343_2376351_+	glutathione S-transferase family protein	NA	NA	NA	NA
WP_085989419.1\|2376466_2379106_-	PAS-domain containing protein	A0A2K9L5I4	Tupanvirus	3.4e-13	28.0
WP_003284516.1\|2379035_2380199_-	FIST C-terminal domain-containing protein	NA	NA	NA	NA
WP_003284517.1\|2380527_2381715_-	porin	NA	NA	NA	NA
WP_014820370.1\|2382008_2384540_-	pyrroloquinoline quinone biosynthesis protein PqqF	A0A1V0SJA4	Klosneuvirus	2.7e-15	29.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_018028

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection