CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017353	Staphylococcus lugdunensis N920143, complete genome	11 crisprs	cas2,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,csm6,cas6,csa3,WYL,DEDDh,DinG,cas3	5	3	7	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_017353_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017353_1

63455-63777

TypeIII

Consensus_repeat	Method
AATCAGAGAATACCCCGTATAAAAGGGGACGAGAAC	PILER-CR
AATCAGAGAATACCCCGTATAAAAGGGGACGAGAAC	CRISPRCasFinder
AATCAGAGAATACCCCGTATAAAAGGGGACGAGAAC	CRT

4 spacers

cas6,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas2,cas1

The CRISPR arrays of NC_017353_1

>merge|NC_017353|1|63455-63777|PILER-CR,CRISPRCasFinder,CRT
AATCAGAGAATACCCCGTATAAAAGGGGACGAGAACTAACACCTTTGATTTTATATCTTTTTCCATCAAATAATCAGAGAATACCCCGTATAAAAGGGGACGAGAACCCAAATAATACTATTAATTTATCTGTTAATGCTGTGGAATCAGAGAATACCCCGTATAAAAGGGGACGAGAACTGGTAAATCTTCTACACTGTCGACTGGGTCTTCTAAATCAGAGAATACCCCGTATAAAAGGGGACGAGAACTGTTCCAATTAGCTAAAGATGTTATGGACGGCAAGAAATCAGAGAATACCCCGTATAAAAGGGGACAAAAAG

>NC_017353|1|1|63455-63705|PILER-CR
AATCAGAGAATACCCCGTATAAAAGGGGACGAGAAC	TAACACCTTTGATTTTATATCTTTTTCCATCAAAT
AATCAGAGAATACCCCGTATAAAAGGGGACGAGAAC	CCAAATAATACTATTAATTTATCTGTTAATGCTGTGG
AATCAGAGAATACCCCGTATAAAAGGGGACGAGAAC	TGGTAAATCTTCTACACTGTCGACTGGGTCTTCTA
AATCAGAGAATACCCCGTATAAAAGGGGACGAGAAC

>NC_017353|1|1|63455-63777|CRISPRCasFinder
AATCAGAGAATACCCCGTATAAAAGGGGACGAGAAC	TAACACCTTTGATTTTATATCTTTTTCCATCAAAT
AATCAGAGAATACCCCGTATAAAAGGGGACGAGAAC	CCAAATAATACTATTAATTTATCTGTTAATGCTGTGG
AATCAGAGAATACCCCGTATAAAAGGGGACGAGAAC	TGGTAAATCTTCTACACTGTCGACTGGGTCTTCTA
AATCAGAGAATACCCCGTATAAAAGGGGACGAGAAC	TGTTCCAATTAGCTAAAGATGTTATGGACGGCAAGA
AATCAGAGAATACCCCGTATAAAAGGGGACAAAAAG

>NC_017353|1|1|63455-63777|CRT
AATCAGAGAATACCCCGTATAAAAGGGGACGAGAAC	TAACACCTTTGATTTTATATCTTTTTCCATCAAAT
AATCAGAGAATACCCCGTATAAAAGGGGACGAGAAC	CCAAATAATACTATTAATTTATCTGTTAATGCTGTGG
AATCAGAGAATACCCCGTATAAAAGGGGACGAGAAC	TGGTAAATCTTCTACACTGTCGACTGGGTCTTCTA
AATCAGAGAATACCCCGTATAAAAGGGGACGAGAAC	TGTTCCAATTAGCTAAAGATGTTATGGACGGCAAGA
AATCAGAGAATACCCCGTATAAAAGGGGACAAAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017353.1\|WP_002479153.1\|73925_74711_+\|tandem-type-lipoprotein	unknown	unknown	gnl\|CDD\|367972
NC_017353.1\|WP_002479159.1\|63970_64324_+\|hypothetical-protein	unknown	unknown	unknown
NC_017353.1\|WP_014533190.1\|77067_77853_+\|tandem-type-lipoprotein	unknown	unknown	gnl\|CDD\|367972
NC_017353.1\|WP_002479166.1\|58215_58641_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|187778
NC_017353.1\|WP_002479160.1\|62515_63268_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NC_017353.1\|WP_002479158.1\|64676_65303_-\|4'-phosphopantetheinyl-transferase-superfamily-protein	unknown	unknown	gnl\|CDD\|225002
NC_017353.1\|WP_002479169.1\|54714_55620_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NC_017353.1\|WP_002479165.1\|58642_59287_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NC_017353.1\|WP_002479168.1\|55619_55925_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09638_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|273699
NC_017353.1\|WP_044019724.1\|55940_58214_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NC_017353.1\|WP_002479148.1\|79174_79501_+\|hypothetical-protein	unknown	unknown	unknown
NC_017353.1\|WP_014533189.1\|76021_76834_+\|tandem-type-lipoprotein	unknown	unknown	gnl\|CDD\|367972
NC_017353.1\|WP_002479164.1\|59297_60206_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|273866
NC_017353.1\|WP_002479162.1\|61233_62202_+\|type-III-A-CRISPR-associated-protein-Csm6	csm6	cd09699_csm6_CAS-III-A	gnl\|CDD\|187830
NC_017353.1\|WP_012990658.1\|65299_72481_-\|non-ribosomal-peptide-synthetase	unknown	unknown	gnl\|CDD\|237108
NC_017353.1\|WP_002460943.1\|79503_79791_+\|hypothetical-protein	unknown	unknown	unknown
NC_017353.1\|WP_002479163.1\|60209_61220_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|187793
NC_017353.1\|WP_002479149.1\|77849_79175_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238287
NC_017353.1\|WP_002460942.1\|80208_81171_-\|L-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|133427
NC_017353.1\|WP_002479161.1\|62180_62519_+\|CRISPR-type-III-a/mtube-associated-protein-csm6	csm6	cd09699_csm6_CAS-III-A	gnl\|CDD\|131720

Protein	Function_ID	Function_description	E-value
NC_017353.1\|WP_002479153.1\|73925_74711_+\|tandem-type-lipoprotein	gnl\|CDD\|367972	pfam04507, DUF576, Csa1 family. This family contains several uncharacterized staphylococcal proteins. These proteins have been called conserved staphylococcal antigens (Csa).	2.26294e-131
NC_017353.1\|WP_014533190.1\|77067_77853_+\|tandem-type-lipoprotein	gnl\|CDD\|367972	pfam04507, DUF576, Csa1 family. This family contains several uncharacterized staphylococcal proteins. These proteins have been called conserved staphylococcal antigens (Csa).	4.24977e-132
NC_017353.1\|WP_002479166.1\|58215_58641_+\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|187778	cd09647, Csm2_III-A, CRISPR/Cas system-associated protein Csm2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-A.	2.41736e-19
NC_017353.1\|WP_002479160.1\|62515_63268_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	8.94533e-13
NC_017353.1\|WP_002479158.1\|64676_65303_-\|4'-phosphopantetheinyl-transferase-superfamily-protein	gnl\|CDD\|225002	COG2091, Sfp, Phosphopantetheinyl transferase [Coenzyme metabolism].	4.43336e-21
NC_017353.1\|WP_002479169.1\|54714_55620_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.06694e-100
NC_017353.1\|WP_002479165.1\|58642_59287_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	2.24262e-98
NC_017353.1\|WP_002479168.1\|55619_55925_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|273699	TIGR01573, cas2, CRISPR-associated endonuclease Cas2. This model describes most members of the family of Cas2, one of the first four protein families found to mark prokaryotic genomes that contain multiple CRISPR elements. CRISPR systems protect against invasive nucleic acid sequences, including phage. Cas2 proteins have been characterized as either endoribonuclease (for ssRNA) or endodeoxyribonuclease (for dsDNA), depending on the system to which the Cas2 belongs. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats. The cas genes usually are found near the repeats. A distinct branch of the Cas2 family shows a very low level of sequence identity and is modeled by TIGR01873 instead of by this model (TIGR01573).	5.19185e-18
NC_017353.1\|WP_044019724.1\|55940_58214_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
NC_017353.1\|WP_014533189.1\|76021_76834_+\|tandem-type-lipoprotein	gnl\|CDD\|367972	pfam04507, DUF576, Csa1 family. This family contains several uncharacterized staphylococcal proteins. These proteins have been called conserved staphylococcal antigens (Csa).	5.7291e-124
NC_017353.1\|WP_002479164.1\|59297_60206_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	2.35132e-36
NC_017353.1\|WP_002479162.1\|61233_62202_+\|type-III-A-CRISPR-associated-protein-Csm6	gnl\|CDD\|187830	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems.	1.67138e-77
NC_017353.1\|WP_012990658.1\|65299_72481_-\|non-ribosomal-peptide-synthetase	gnl\|CDD\|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NC_017353.1\|WP_002479163.1\|60209_61220_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	8.37294e-16
NC_017353.1\|WP_002479149.1\|77849_79175_+\|hypothetical-protein	gnl\|CDD\|238287	cd00519, Lipase_3, Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site. .	0.00408836
NC_017353.1\|WP_002460942.1\|80208_81171_-\|L-lactate-dehydrogenase	gnl\|CDD\|133427	cd05291, HicDH_like, L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases. L-2-hydroxyisocapronate dehydrogenase (HicDH) catalyzes the conversion of a variety of 2-oxo carboxylic acids with medium-sized aliphatic or aromatic side chains. This subfamily is composed of HicDHs and some bacterial L-lactate dehydrogenases (LDH). LDHs catalyze the last step of glycolysis in which pyruvate is converted to L-lactate. Bacterial LDHs can be non-allosteric or may be activated by an allosteric effector such as fructose-1,6-bisphosphate. Members of this subfamily with known structures such as the HicDH of Lactobacillus confusus, the non-allosteric LDH of Lactobacillus pentosus, and the allosteric LDH of Bacillus stearothermophilus, show that they exist as homotetramers. The HicDH-like subfamily is part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	5.16566e-165
NC_017353.1\|WP_002479161.1\|62180_62519_+\|CRISPR-type-III-a/mtube-associated-protein-csm6	gnl\|CDD\|131720	TIGR02672, hypothetical_protein_SERP2456, CRISPR type III-A/MTUBE-associated protein Csm6. Members of this family as found in CRISPR-associated (cas) gene regions in Streptococcus thermophilus CNRZ1066, Staphylococcus epidermidis RP62A, and Mycobacterium tuberculosis (strains CDC1551 and H37Rv), as part of Mtube-type CRISPR/Cas systems. CRISPR is a widespread form of direct repeat found in archaea and bacteria, with distinctive subtypes each of which has a characteristic sporadic distribution.	4.28908e-23

>NC_017353.1|WP_002479160.1|62515_63268_+|CRISPR-associated-endoribonuclease-Cas6
MIYKITVQLNLPNNINLPYMGSILHGVLMDYLSNDIASSLHHNFAYSPLKQRVFYFEDKKIWEIVSMSEELFNELVNLFNKENKIYLKHYKSTVSIEKYSVEKISIQKLIDTFLHKRDLSRYIKINVSTPMSFKLNNQYMIFPNVKRFFRSIMIQFDAFFESHKLYDKETLEFLEQNVNIVNYKLKSVRFHMEKVKIPSFKGEIVFKINGPLPFLQLVYFLLAFGEFSGTGIKTSLGMGKYNIVDKNQDN
>NC_017353.1|WP_002479161.1|62180_62519_+|CRISPR-type-III-a/mtube-associated-protein-csm6
MHLQKRIKKEDIINIDVSKNTLGLPAFIDILSLLQPKSKLLKEVRPVNDINGLRNSVAHNLDMLNLDSNKNYKKIELAVKAIQNMLITTFSEIEEEDFEYLTEKNKELKGLL
>NC_017353.1|WP_002479162.1|61233_62202_+|type-III-A-CRISPR-associated-protein-Csm6
MKVLFSPIGNTDPWSNERDGAMLHIVRHYRPEKVILFFTESIWFGNENIPGRKQFEWEKIVSKVSPQTSVEIKVENIEHEHDFDSYKDLFSYFIKGIRMSNPESEILLNVTSGTPQMESTLCLEYISNPNNAQCIQVSAPQPSNNTKRLYANPNNAFKDLEKVNQNEHLADNRCKSINILSFREVMVRSQVRGLIDNYDYEGALNLISAQKSFRNGKVLQKKLRNLTTQIKTHKIFSDLSERYSNEALKKSLFHYLLLKMRHDRLDVAETLIRVKSIAEYIIKYYIQSNWPSLILEENGKPKLNVKKMLLLYININCIYKSV
>NC_017353.1|WP_002479163.1|60209_61220_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MTIKTFDAIIQTIGPIHIGSGQVLKKQDYIYDFHKSKVHMINGNQLVKVLKRKNLLNMYQEFLRYPPKNPRENGLKNFLEAHKITQSEWKEFISYSESVNQGKKYGNIKPKPLNDLHLMIRDGQNKVYIPGSSIKGAIKTALVSKYDNENDKSVFSRIKISDSEPVDESNLAIYQKIDINKDEKPMPLYRECIDVNTQIKFKITIEDNQYSIEDIENCIQDFYKNYYNQWLSRFKNTRGGQKFILEGGMPEVKGQNILYLGGGVGFSSKTTHYQTKSHEQAKHDTFEILRKRFRGTYGKMKRIPQNVPVALKGTLNYSKNQSYQQGMCQITFKKND
>NC_017353.1|WP_002479164.1|59297_60206_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MITKIFKLSFKTPVHFGKKRLSDGEMTIKADTLFSALYTETLNLGKQTNWLMNDLIISDTFPYESELYYLPKPLIKIESNSEGNHKDFKKLKYVPVYNYNDYIKGQLSEEDVRDLNDIFRVGQFSLQTKVSLKAQEQSPNEDSEPYSVGTFSFEKDAGLYFIAKGSERTIQRLNEVMYALQFSGIGGKRSAGYGRFEYTCVSNENISNLLNQDGDNFILLSTSMAKREELEASLNKARYILSKRTGFIQSTTYSDRLVKKNDFYSFSVGSVFKTIFKGDIFNVGNQGQHPVYRYAKPLWMEV
>NC_017353.1|WP_002479165.1|58642_59287_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MYSKIKVTGTIEIITGLHIGGSGEISMIGAIDSPVVRDLLTKLPIIPGSSIKGKMRSLLARDFGLKLNQDNHNQDDDRVLRLFGSSEKGNIQRARLQISDAFYSDKTKQIFTDNDISFTETKFENTINRLTAVANPRQIERVTRGAEFDFTFIYNVIDETQVEDDFNNIKKAILLLENDYLGGGGTRGNGRIEFKDINIETVVGEYDSTNIKIK
>NC_017353.1|WP_002479166.1|58215_58641_+|type-III-A-CRISPR-associated-protein-Csm2
MILAKTKSGKIIDLNFAHEVVKNNLKMEKDKRGKEELKLFSGLTTSKLRNLMEQVNRLYTMIFNSTEEKLSRNFIDELEYLKIKFYYEAGREKSVDEFLKKTLMFPIIDKVIQKESKKFFLDYCKYFEALVAYSKYYQKED
>NC_017353.1|WP_044019724.1|55940_58214_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MNKKTVLMYGSLLHDIGKIIYRSNDQPYAKGTHSELGYQFLSQFSAFKNKELLDSLAYHHYKELPKANLSSDNTAYITYIADNIASGVDRRDVIEEGDSEYEKQTFNFDKFTPLYSIFNIVNSEKYKYTEGKYRFSKENNIEYPKNEDVRYTSGNYTNLIEDMRYDLEHKIKVTEKNFPSLLQWTESLWQFIPSSTNKNQLIDISLYDHSRITCAIASCIFDYLYENSIDNYKEELFLKYEKTKEFYQKQAFLLLSMDMSGIQEFIYNISGSKALKSLRSRSFYLELMLEVIVDKLLERLKLTRANLLYTGGGHAYLLIANTDKTKTIIKDFISELKQWFLSEFTTDLSLSIAYEACSGDDLMNSNGNYKSIWRNVSNKLSDSKAHKYSYEDILLLNSHSSFGDRECKECLRSDIEINDDGLCSICEGIISISNDLRDKAFFVLSDNGKLKMPFNKYISVISYQEAENLVNRDDSVRIYSKNKPFVGEGIATNLWMCDYDYASNDKSLRAKGIGSYTERKEGIKRLGVVRADIDNLGATFISGIPESYNSISRTATLSRQLSLFFKYELNNLLENYLITSIYSGGDDLFLIGAWDDIVEASVYVNEKFNEFTLGKLTMSAGVGMFSGKYPVSKMAFETGLLEESAKKGEKNQIALWVEEKVYNWDKFKHNILEDKLVVLQQGFLKSDEHGKAFIYKMLNLLRNNEVINIARLAYLLSRSEMSDEFSSKIFYWAQNEEDKEQLITALEYYVYQIREAN
>NC_017353.1|WP_002479168.1|55619_55925_+|CRISPR-associated-endonuclease-Cas2
MFLLISFDLPRDTKYERKIANKYRLRLLELGFSMKQFSLYERYTSDTQKKDKILSILKEEMPNTGKITMYVLPDEVNNKQITILGKEAKIINYKEPKLIFI
>NC_017353.1|WP_002479169.1|54714_55620_+|type-II-CRISPR-associated-endonuclease-Cas1
MKNIIYVENHYFVTAKDNSIKFRNIIDKTEKFYFFSDIEAIIFDHYRSYFSHKLVIKCMQNNIAILFCDNKHSPMTQLLSEYGMSNRIQRIQTQFRFSGRSKERVWKKIVVGKIINQARCVENNIDKSKSIVLKELAKEVKPGDNNNREAIAAKIYFRDLYGPQFKRGRYNDIINSALNYGYSIIRSFIKRELAIHGFEMSLGIKHHSTENPFNLADDVIEVFRPFVDNMVYNIVMKDGVKVFDTKEKKVLLNVLFEKCIIDKKIVRLLDSIKIMIDSLIRCYKENTATYLLIPKMIEVGN
>NC_017353.1|WP_002479159.1|63970_64324_+|hypothetical-protein
MEEVLDLIINLVKLFIIVPYWLISVGVTAFFYFKLVVFIRNTFKAFFDKYFYGEDSDSIPYAVGPYIMIITAMLIGLGIVMVIVLFFNALLGQNLYTLLFIVGVILLIIKFKRGYKN
>NC_017353.1|WP_002479158.1|64676_65303_-|4'-phosphopantetheinyl-transferase-superfamily-protein
MKLFITQMNHTYKDIAHWMSQSHRQLKKPERLTYRFSKDKWMHRIGDLLIQYSIEHTHGLMPSQWSYDIQPNGHVKIASPIDIYVNLSYSFPYIICAIDHLPIGADIEEIKGMDDLNIAKQFSTNEFNQIQTLEDFYTIWTKKESYSKMIGEGLIRGLAYYDVTKPLYYQHHTIKFKQHLIDNCIIQLCHISSNHPFEIVDVPLKQLF
>NC_017353.1|WP_012990658.1|65299_72481_-|non-ribosomal-peptide-synthetase
MNKQLLNFQKYFYLKYLKQSSSTHRMTYWVKLDTRIDCHQLVYALLNVVQHQPVLRSQFNIDDSDDLCVSIREFFPFIELKAFDDYSKNIDIESFFQQKLNSYYLNQLPQFNFTIYQFLDEAYLLLDFHSMIFNDNQLQIFLSELNKAYKHSLNQHAGISQFYMTVQKINEKACNPNAPKDFNQFKVLHADNENYAYMPVKNVSDKKEMRYVRTQLSSFDIHRLAVSTYLAHHFMSQSNEVALNIHFPVANKQSELLMVPNSNVSPVCLYIDQHASVDSLLTAWTSAIHSLQNHGASFITEANADVMELESMFHVTPVVADFELHQVSHEVHRLYNNKSSLANIEIYPLANGGFDLVYDANAYDDLTIQTLRRLITTIYMQSVNQPTMLVQEIQLNDQTDLQLYERINSHSMTQLNGNDAYQTVMSRFEYQVNQHPDAIALQFEQQSMTYRQLNQQANYIAHLLRTTYGIQPNDTVALIMERSMEMIVAILGILKSGAGYLPIDPDYPQERTHYILKDAMPKAIITYHITLQSDLPLIKMEEINWEECTYIDNLPHINTPEDTAYVIYTSGTTGKPKGTVIAHRGIDRLVHQPNYVELNDDTVILLSGTIAFDAATFEIYGALLNGGRLIITSKDTLLDSKQLGQTIADKQVNTMWLTSSLFNQIASERIEVLESLKYLLIGGEVLNAKWVNLLNSRARHPQIINGYGPTENTTFTTTYAIPPKLPARIPIGSPINGTTVYVIQGQRLCGVGVPGELCIGGSGLAKGYLNQPEQTQQSFVKSPLNGEAIYKSGDLVRLQEDGNIDYISRIDKQVKIRGFRIELSEIEKAIEAIRDINKAVVVVHEHEQDRDKQIVAYYEASQPQSTSTLKKLLSHTLPNYMIPVHFMKIDKIPITINGKLDTRALPDIDMIDESNYVAPRNELERVLCRIFEEILHVDRVGIKDNFFELGGHSLRATLVVNRIEEQLQKRLKVGDIMKSPTVKALSQQLKETQNEHYEVIPKASEDTQYELSAVQKSMYLLWSVNPKDTVYNIPFLWRLTSELNVNQLQRSLSQLIQRHEILRTQYIIDHNEVKQRIAKDVIPDFEEVTTDLTDEQDIIHAYTHPFNLEKPSQIRMKYIHSPEHHYLFIDTHHSINDGMSNTILLADLNALYQNKSLPQLSLQYRDYSEWMAQRDLSTQRHYWLEQFEDGVPVLNMPTDYPRPSIKTTHGHMMTFHYDQTFKSQLKSYVEQHQITDFMFFASAIMVLLHKYTRQDDLVIGSVISSRTHRDTENMLGMFANTLVYRGQPSNDKPWEQFISEMKETSLAAYEQQEYPFESLVNDLVGDRDPSRNPLFDVMLVLQNNETNHANFGHSRLTHIPPQSTTAKFDLSFIIEEDYNDYTVNIEYNTDLYSKATIQLMAQQLENIFKYVITTSNPKIKEIQEDPHILDWINTNVNCYTRDDTTHETVQQRFNRVVKQHSEDVALRMNGQSMTYQTLDAYANQLAYELTVNGVQSGDRIALLTERSFEMIISMVAAIKVGASYVPIDVAHPDKRIDYMIKDAQASAVITYGKDIHMNIPTIALETLELTNNNKRPFSEYAGSLEDEIYCIYTSGTTGMPKGVSIQQSNILNLVNAWTDRLELSEHETIIQYSNYVFDASAMDIYSSLLNGHTLVIANKNERTNTELLEQLITKEAITVASIPLQVLNVMHQFYIPKIITGGATSTPSFVQHISKHCDTYYNAYGPSESTVVTTTWSHAKGDPIPSTIPIGQPLANIQVYIVSEMQLCGIGIAGELCIAGDSLAAGYLNQPELNAQAFIDNPFGTGKLYRSGDLARFTPDGNIEFLGRIDKQVKVNGYRIELEEIENVINALDGVDDSVVIIRQQGGHDLLHAYYVGNHDIASHLLKQLTQYLPKYMIPNTFTAIDEIPLTSNDKVDESKLPNPEMHHHQFEPPRNDTEQIFASIMAEILDISEIGIDDDFFKLGGSSLDTMVLISKLKRKHIHLTMQDIYQYKTIRHLSAHLEQQSDESCVTLPDHLPQLQSLIKQRYQMRSKPMIVRHLGHVLLTGATGFLGAYLINELTGYTDKITCVVRGQNKKDARQLVEENLSCYFDPAHVADLMIRVEVVLGEFSNLDILNITSHIDTIIHAGARTDHFGDDEAFINVNVKSTEDLLTLAETHKARFIYISTISVGTVFDSHAEDYTFSEQDLYKGQLFTSPYTKSKFYSEIKVLEAIEAGLDAQIMRLGNLTSAYTGKLNMKNLTTNRFSIVMNDLLKLPFIGDSFSQTEIEFSFIDITARDIVTLAISNATPIIYHVYSPHVLTMKNVLEETKDTDLPLINDEEFDKALHELNMHEVIGLNSQASNQITGVTQSSMTQNLLRDLDEVWPKVTQHWLYQWRELLNEKFECKEYHR
>NC_017353.1|WP_002479153.1|73925_74711_+|tandem-type-lipoprotein
MRQSRKLKLGICLILLIILIGSCIILTKTNSRNAQIKKTFNQTLSLYPTKNLEDFYDKEGFRDQEFDKGDKGTWIIHSEMVIEPKGRNMESRGMVLHVNRNTRTTKGYFLISEITEDKKGYVHNKDKKYPVKMEHNKIIPIKPIPNDKLKKEIENFKFFVQYGNFKDFKDYKNGDISYNPNVPSYSAKYLLNNDDYNVQQLRKRYNIPTKQAPELKLKGDGDLKGSSIGSKDLEFTFVENKKENIFFTDSVQFTPSEVNKS
>NC_017353.1|WP_014533189.1|76021_76834_+|tandem-type-lipoprotein
MRQSRQLKLGICLILLIILIGGCVILTKINNRNAQIKESFNKTLSLYPTKNLEDFYDKEGFRDQEFEKGDKGTWIVNSEMVIGPKGKNMESRGMVLYINRNTRTTKGYYFISETTYDNNGRPKDDEKRYPVKMAHNKIIPTKRIPDDKLKKEIENFKFFVQYGNFKDFKDYKNGDISYNPNVPSYSAKYLLSNDDYNVQQLKKRYNIPTKQAPELKLKGDGDLKGSSIGSKDLEFTFVENKKKISFLQILYNLLQVRIINHESNGISNKV
>NC_017353.1|WP_014533190.1|77067_77853_+|tandem-type-lipoprotein
MRQSRKLKLGICLILLIILIGGCIILTKTNSRNAQIKKTFNQTLRLYPTKNLEDFYDKEGFRDQEFEKGDKGTWIIYSKMIIEPKGRNMESRGMVLHINRNTRTTRGNFIVNEITEDSKGRPLNNKKKYPVKMEHNRIIPTKPIHDDKLKKEIENFKFFVQYGSFKDFKDYKNGDISYNPNVPSYSAKYQLSNDDYNVQQLRKRYNIPTKQAPELKLKGDGDLKGSSIGSKDLEFTFVENQEENIYFTDTVQFTPSEVDKT
>NC_017353.1|WP_002479149.1|77849_79175_+|hypothetical-protein
MNQTEYKIKPGNIKGNSEETSTVSKISYEIENANNSGLKRDKINEQIEGLKEYDKFPGNLEYVDSYTDPKTGTTTSAFLNKETGKVTLGMTGTNLHKGAMLKQAFGVASPQDYRDVYETLNDIRADINIGLHSVTDKDPHYKNTQDFIKGIKKDYDIDTITGHSLGGRDAIILGTSNDIKHIVVYNPAPLAVKDVSILYDDGEELKKMIEKYDGHIVRFVSNQDILDAGVRDLMYETAGEKIVIKNGEGHSMDGFLIKGTQAKILAELKRVKGYQDANNKSFKSVRKQTRRRLDKVETLRANWIQTNGGALSSSQQQLLESLTALTIAQGLSQLVDEESQHLKKMYQSMAHKFGENWKKAQEAGNEIAEKLTFAEVIDELRAGGAYESKLETDPQRKIDNKLKKLNDVSKNCDDYIAKIKQSIHAIVEKDKALASQIGGIM
>NC_017353.1|WP_002479148.1|79174_79501_+|hypothetical-protein
MFTEYKKLSDLENAFDVERKKLNDELNQLYELKHQTRRKCEQMYDHFLYLKHKLNYSEAATIKMTRIIEAFDGEMNQRIRHQEMKLEDDKDTLRRDYLKQSARIEGDE
>NC_017353.1|WP_002460943.1|79503_79791_+|hypothetical-protein
MIRGSNAIPDLAVMGGMMEKEQIRTVIAPEHDRMHHDHQNKLKSDEKILLDQMVSHFKKFEGEFKNAAQGDWVKSAMSELNDISDDLKHIQDIEV
>NC_017353.1|WP_002460942.1|80208_81171_-|L-lactate-dehydrogenase
MKAFGKKVVLIGDGSVGSSYAFAMVTQSVADEFVIIDIATDKVNADVQDLNHGTAHCPSPVNISAGTYSDCKDADLVVITAGAPQKPGETRLQLVEKNAKIMKDIVKSVMDSGFDGYFLIAANPVDILTRFIKEYTGLPAERVIGSGTVLDSARLQYLISREFDVAPASVNASIIGEHGDSELAVWSQANIAGMPVFEALKEKTGSEAKAEEIYVNTRDAAYEIIQAKGSTYYGIALALMRISKAILNNENNVLNVSTQLTGQYGGYRDVYVGVPTLVNQDGAVKIYELPLDEKEKALFDQSVKTLEDIYNSIKYLLEDK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017353_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017353_2

395626-395709

Orphan

Consensus_repeat	Method
AACCCCAACTTGCTTTGCTTGGCGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017353_2

>merge|NC_017353|2|395626-395709|CRISPRCasFinder
AACCCCAACTTGCTTTGCTTGGCGAATTTCTGCTCGAAATTCTCTTTGTTGGGGCCCCAACCCCAACTTGCTTTGCTTAGCGAA

>NC_017353|2|2|395626-395709|CRISPRCasFinder
AACCCCAACTTGCTTTGCTTGGCGAA	TTTCTGCTCGAAATTCTCTTTGTTGGGGCCCC
AACCCCAACTTGCTTTGCTTAGCGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017353.1\|WP_002478542.1\|397968_398529_-\|GbsR/MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224427
NC_017353.1\|WP_002478548.1\|406935_409560_+\|pyruvate,-phosphate-dikinase	unknown	unknown	gnl\|CDD\|236446
NC_017353.1\|WP_002478549.1\|409564_410380_+\|kinase/pyrophosphorylase	unknown	unknown	gnl\|CDD\|235419
NC_017353.1\|WP_002478545.1\|402432_403611_+\|amidohydrolase	unknown	unknown	gnl\|CDD\|349941
NC_017353.1\|WP_002478533.1\|385105_385717_+\|NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|180667
NC_017353.1\|WP_002478535.1\|387851_388451_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NC_017353.1\|WP_002478538.1\|391333_393181_+\|anaerobic-ribonucleoside-triphosphate-reductase	unknown	unknown	gnl\|CDD\|236436
NC_017353.1\|WP_002478547.1\|405094_406687_+\|acyl--CoA-ligase	unknown	unknown	gnl\|CDD\|341276
NC_017353.1\|WP_002478534.1\|386656_387835_+\|sulfate-adenylyltransferase	unknown	unknown	gnl\|CDD\|235227
NC_017353.1\|WP_002478546.1\|404008_404458_+\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|225209
NC_017353.1\|WP_002478540.1\|394075_395368_+\|anaerobic-C4-dicarboxylate-transporter	unknown	unknown	gnl\|CDD\|236503
NC_017353.1\|WP_002478537.1\|390364_391135_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NC_017353.1\|WP_002460576.1\|403749_404019_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369110
NC_017353.1\|WP_002478532.1\|384305_385085_+\|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl\|CDD\|235711
NC_017353.1\|WP_002478544.1\|400478_402185_+\|choline-dehydrogenase	unknown	unknown	gnl\|CDD\|235000
NC_017353.1\|WP_002460596.1\|385734_386634_+\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NC_017353.1\|WP_002478543.1\|398896_400387_+\|betaine-aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143437
NC_017353.1\|WP_002478539.1\|393182_393719_+\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	unknown	unknown	gnl\|CDD\|379137
NC_017353.1\|WP_002478536.1\|388755_389976_+\|ArgE/DapE-family-deacylase	unknown	unknown	gnl\|CDD\|181490
NC_017353.1\|WP_002478541.1\|396290_397916_+\|BCCT-family-transporter	unknown	unknown	gnl\|CDD\|224211

Protein	Function_ID	Function_description	E-value
NC_017353.1\|WP_002478542.1\|397968_398529_-\|GbsR/MarR-family-transcriptional-regulator	gnl\|CDD\|224427	COG1510, COG1510, Predicted transcriptional regulators [Transcription].	2.16217e-62
NC_017353.1\|WP_002478548.1\|406935_409560_+\|pyruvate,-phosphate-dikinase	gnl\|CDD\|236446	PRK09279, PRK09279, pyruvate phosphate dikinase; Provisional.	0
NC_017353.1\|WP_002478549.1\|409564_410380_+\|kinase/pyrophosphorylase	gnl\|CDD\|235419	PRK05339, PRK05339, pyruvate, phosphate dikinase/phosphoenolpyruvate synthase regulator.	2.33637e-122
NC_017353.1\|WP_002478545.1\|402432_403611_+\|amidohydrolase	gnl\|CDD\|349941	cd08021, M20_Acy1_YhaA-like, M20 Peptidase aminoacylase 1 subfamily, includes Bacillus subtilis YhaA and Staphylococcus aureus amidohydrolase, SACOL0085. Peptidase M20 family, uncharacterized subfamily of bacterial proteins predicted as putative amidohydrolases or hippurate hydrolases. These are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. Aminoacylase 1 (ACY1) breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine). This family includes Staphylococcus aureus amidohydrolase, SACOL0085, which contains two manganese ions in the active site, and forms a homotetramer with variations in interdomain orientation which possibly plays a role in the regulation of catalytic activity.	0
NC_017353.1\|WP_002478533.1\|385105_385717_+\|NAD(P)-binding-protein	gnl\|CDD\|180667	PRK06718, PRK06718, NAD(P)-binding protein.	4.14708e-121
NC_017353.1\|WP_002478535.1\|387851_388451_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	1.60037e-138
NC_017353.1\|WP_002478538.1\|391333_393181_+\|anaerobic-ribonucleoside-triphosphate-reductase	gnl\|CDD\|236436	PRK09263, PRK09263, anaerobic ribonucleoside triphosphate reductase; Provisional.	0
NC_017353.1\|WP_002478547.1\|405094_406687_+\|acyl--CoA-ligase	gnl\|CDD\|341276	cd05972, MACS_like, Medium-chain acyl-CoA synthetase (MACS or ACSM). MACS catalyzes the two-step activation of medium chain fatty acids (containing 4-12 carbons). The carboxylate substrate first reacts with ATP to form an acyl-adenylate intermediate, which then reacts with CoA to produce an acyl-CoA ester. The acyl-CoA is a key intermediate in many important biosynthetic and catabolic processes.	0
NC_017353.1\|WP_002478534.1\|386656_387835_+\|sulfate-adenylyltransferase	gnl\|CDD\|235227	PRK04149, sat, sulfate adenylyltransferase; Reviewed.	0
NC_017353.1\|WP_002478546.1\|404008_404458_+\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	1.02761e-21
NC_017353.1\|WP_002478540.1\|394075_395368_+\|anaerobic-C4-dicarboxylate-transporter	gnl\|CDD\|236503	PRK09412, PRK09412, anaerobic C4-dicarboxylate transporter; Reviewed.	5.28088e-156
NC_017353.1\|WP_002478537.1\|390364_391135_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.1351e-25
NC_017353.1\|WP_002460576.1\|403749_404019_+\|hypothetical-protein	gnl\|CDD\|369110	pfam06855, YozE_SAM_like, YozE SAM-like fold. YozE-like is a family of Firmicute proteins that carries a four-helix motif similar to sterile alpha motif (SAM) domains. The family is suggested to fall into two subfamilies, possibly with differing functions based on the different surface charges on the three structural representatives, YozE MW0776 and MW1311. What this function is is not yet known although it is likely to involve binding to DNA.	2.54746e-10
NC_017353.1\|WP_002478532.1\|384305_385085_+\|uroporphyrinogen-III-C-methyltransferase	gnl\|CDD\|235711	PRK06136, PRK06136, uroporphyrinogen-III C-methyltransferase.	5.78933e-124
NC_017353.1\|WP_002478544.1\|400478_402185_+\|choline-dehydrogenase	gnl\|CDD\|235000	PRK02106, PRK02106, choline dehydrogenase; Validated.	0
NC_017353.1\|WP_002460596.1\|385734_386634_+\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.21611e-29
NC_017353.1\|WP_002478543.1\|398896_400387_+\|betaine-aldehyde-dehydrogenase	gnl\|CDD\|143437	cd07119, ALDH_BADH-GbsA, Bacillus subtilis NAD+-dependent betaine aldehyde dehydrogenase-like. Included in this CD is the NAD+-dependent, betaine aldehyde dehydrogenase (BADH, GbsA, EC=1.2.1.8) of Bacillus subtilis involved in the synthesis of the osmoprotectant glycine betaine from choline or glycine betaine aldehyde.	0
NC_017353.1\|WP_002478539.1\|393182_393719_+\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	gnl\|CDD\|379137	pfam13353, Fer4_12, 4Fe-4S single cluster domain. This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.	6.95633e-57
NC_017353.1\|WP_002478536.1\|388755_389976_+\|ArgE/DapE-family-deacylase	gnl\|CDD\|181490	PRK08588, PRK08588, succinyl-diaminopimelate desuccinylase; Reviewed.	0
NC_017353.1\|WP_002478541.1\|396290_397916_+\|BCCT-family-transporter	gnl\|CDD\|224211	COG1292, BetT, Choline-glycine betaine transporter [Cell envelope biogenesis, outer membrane].	0

>NC_017353.1|WP_002478540.1|394075_395368_+|anaerobic-C4-dicarboxylate-transporter
MILFAIEIGIMIAAILLGLRTAGALGCGIFAIVAQLIMIFVFQLPPGSAPVTAVLIILSIGIAGGTLQSTGGIDYLVYLASKVIEKYPKSIIFISPIIVFIFVFGIGTANIALSLEPIIAKTAMKAGIQPRRPLIASVLTANLALLCSPAAAATAYIISVLAGYDISMGKYLSVVFPTAILTMLLLSVFCTLAGRKKEQAQRFELKDLEVKVPTTFPSKVKLGVASFLLCVVGILTFGIFPQLMPSFNIDGKSVEVTMTEIVQFFMYLAAAINLLLNKIDTTDILSSHITQSAIGALFAVLGPGWLGATVFNAPQNLKILKEDVGAVIQVAPWLVILLVSIVAIVVISQTATASIMFPIVLSIGIPPMFFVAMVQTINVNFVIPAQPTLLFAVDLDETKRTKVTSFIIPGFFMITVSVLIGFSIKAILGY
>NC_017353.1|WP_002478539.1|393182_393719_+|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein
MSVLDVTEGRGYIAKIEQHSFVDGEGVRVSMYVSGCPFLCEGCYNVAAQRFTYGEPFNDETLEAILHYCEPDYIAGLSILGGEPFCNVDITLKVARAFRQKFGHRKSLWVWTGFLYEYLSHDAGIRHQLLSLIDVLVDGPFIQALFQPNLAYKGSLNQRVINVPASLKKGTPVIYVED
>NC_017353.1|WP_002478538.1|391333_393181_+|anaerobic-ribonucleoside-triphosphate-reductase
MKQLEAELQGLITKDPAIVNENANKDSNTFSTMRDLTAGVVSKSYALQHLLPKRVAQAHKNGDIHFHDLDYHPFQPLTNCCLIDATSMLQHGFEIGNANVTTPKSIQTASAQLVQIIANVSSSQYGGCTVDRVDELLSTYARHNEAHHRKVAETFVRADAIEDYVDQQVTKDVNDAIESLEYEINTLYTSNGQTPFVTLGFGLGTDKLSRKIQQAILNTRIKGLGKNRITAIFPKLVFTIKKGVNFSEEDPNYDVKQLALKCSTKRMYPDVLNYDTLVDILGDFKAPMGCRSFLPAWRDAQGQFENSGRCNLGVVTLNIPRIAIESQGDKLTFWRLFHERMDILHEALLYRIERVAQAVPENAPILYKSGAFKYKLQEGEDVTDLFKHRRATISMGYIGLYEAATVFYGPNWETNPDAKAFTLDILKEMKDYQLEWTEETDVWFSIYSTPSESLTDRFCRLDYERFGSIPDITDKGYYQNSFHYDVRKDITPFEKIDFEKDYPYYASGGFIHYCEYPKLNHNLKALEAVWDYAYDKVGYLGTNIPIDRCYECGYEGDFETTAQGYTCPHCGNHDPKTVDVVKRTCGYLGNPVQRPVIEGRQKEICARVKHMKEPK
>NC_017353.1|WP_002478537.1|390364_391135_+|CHAP-domain-containing-protein
MKKIATATIATAGFATIALAGGHDAHAAEQNNNGYNPNDPYSYSYSYTIDQQGNYHYTWQGNWSPNQAQQGQYYSYNYTNTAGTQNYNYNTQYSQNYQPQTQAYHANNGGGLGASYSTSDRNVKVTTTQAPSSHASNTSGGSAFSGKSGSSSNLYTAGQCTYYVFDKVGGKIGSTWGNASNWASAAASEGYNVSNSPKQGAVMQTSQGAYGHVAYVEKVNSDGSVKVSEMNYNGGPGVVSTRTISASQASSYNYIS
>NC_017353.1|WP_002478536.1|388755_389976_+|ArgE/DapE-family-deacylase
MTVLSEQERIDILADIVNINTENNNEIEVCYYLKELLQRYDIESKIIEIEGKRSNLVAEIGSGRPVIGISGHMDVVDAGDEAQWMYPPFELHEQDGKLYGRGTSDMKGGLAALVIAMIEIKASNLLQQGTIRLLATAAEEKEMSGSMLFRDKGYVDDLDGLIIGEPSDHYINYANKGSMGIKIKAKGVAAHSSLPNLGHNAIDDIIRYIQKIKEKYEDIKNNDNKHSLDVSPLIKDYFGDKFNDKELRKLENVAEGLVIVNSIIYGGEQFNTVPESAYAEFNIRTIPEYDNEAIIQLFEETLYEVDQAQLSMEITTNHAPVYSNKDNLLVKSFTEYKDDLTVTALVGATDASELLKGIDNVDLTIIGPGFMRQAHRANEYIDKQHYLDFIDLYQHVIVDYLNKKSN
>NC_017353.1|WP_002478535.1|387851_388451_+|adenylyl-sulfate-kinase
MSQSSHITWHDSEVTKADRQKQNGHKSAVIWFTGLSGSGKSTVSVALEQALFELGKHAYRLDGDNVRHGLNKNLGFSPEDRKENIRRIGEVSKLLVDAGTIAITAFISPYRVDRDDVRNILEDGEFIEVYTQCSVEECEKRDPKGLYAKARSGEIKEFTGINAPYEAPYHPEITINTEQQSVEQAVAHILNYLTDNKYL
>NC_017353.1|WP_002478534.1|386656_387835_+|sulfate-adenylyltransferase
MSVSKDILHYTIKPHGGVLINRVVEGIERTQLSQAAQSYKAITLNPWAISDLELIAIGGFSPLTGFMGQEDYNQVIEKTHLTDGSVWSIPITLPVTEDVASKLEIGDHIALYGEDGALYGTLKLTEKYTYDKKREAQLVYGTTDVKHPGVKKVYDKGNVYLAGPIQLLKRPQHNKFADYHLDPHETRQLFHDLGWKTVVGFQTRNPVHRAHEYIQKSALEIVDGLLLNPLVGETKADDIPADVRMESYETILKHYYPKNRARLVIYPAAMRYAGPKEAVLHAIVRKNYGCTHFIVGRDHAGVGDYYGTYEAQQFISQFEDELDIQILKFEHAFYCEACGNMATAKTCPHDATQHVHLSGTKVREKLRNGEALPTKFSRPEVAEVLIKGLQQH
>NC_017353.1|WP_002460596.1|385734_386634_+|sulfite-exporter-TauE/SafE-family-protein
MKKLLIFALAGFLAQLVDGSLGMGFGASSSSILLTYGITPAIVSATVHFSEIATTAASGTSHWKFDNVHRSTMLKLAIPGAIFGFLGAAFLTHIHSSVIKPYIAIFLLAMGFYILYQFLFRRQHETHEHVGQLSGWKLIPQGAIAGLLDAIGGGGWGPVNTPILLSSKKIQPRYAIGTVSASEFFVTLATSLSFILFLGITQINWWLVVALSIGGMAAAPISAYLTKILPINILAICVGGLIIFTNSNALLSYFVDNSTIINVIRFAIICSILVLIIFVAIRNRLLSFSYKKNRVNKYN
>NC_017353.1|WP_002478533.1|385105_385717_+|NAD(P)-binding-protein
MNMPLMVDLAGQRIVIVGGGQVAARRASNFIDYCQDIHIISPQVHSSLEDLINAGQITWHQKEFDAADIAGAFLVVAATNNKAVNQQVKALVPPGCLFNNAEDATSGNVTIPNILKRGKLTLSVATQGASPKLGIQIIEQLSHTYDERYEQYVEFLYQCRQTLKRINIEPSYRQALLAKIVSDDYLDLDKQQAFLRWLQAQAE
>NC_017353.1|WP_002478532.1|384305_385085_+|uroporphyrinogen-III-C-methyltransferase
MGKVYLVGAGSGDPELITVKGLKAIKQADVILYDRLVNRELLDYATAGTKLFYCGKDPNRQSLPQSETNKMLVSLAKKGHTVTRLKGGDPFVFGRGGEEAEILAQHHIAFEIIPGITAGIAAPAYAGIPVTHRDFSSSVAFVTAVNKPGMTKAAYWEHLAHGPETLCIYMGVKRLSEICGLLIKYGKPIDTPVALIHLGTTAYQQTVTGTLSTITEVAKNIKNPAMIVIGQVVQMHDKIQWFTEQTEQMRMDYSQVNSK
>NC_017353.1|WP_002478541.1|396290_397916_+|BCCT-family-transporter
MKKEKIMDWPTFIGTVVILLLAVIPMMAFPSASEKVITDINSAISNSIGSLYLFIGLAILCFVLYIAFGKYGNVTLGKASDKPEFSNFSWASMLFCAGIGSDILYWGVIEWAYYYQVPPNGAKPMSDQALTFATQYGMFHWGPIAWAIYVLPALPIGYLVFVKKQPIYKISQACRPVLKGQTDKFLGKLVDVLFIFGLLGGAATSLALGVPMISAGVEKLTGLDGQNMVLRSIILFTITVIFAISSYTGLKKGIQKLSDVNVWLSFLLLGFVFIVGPTIFIMETTITGFGNMLRDFFHMATWMEPFGGIKGRKETNFPQDWTIFYWSWWLVYAPFIGLFIARISKGRRLKEVILGTIVYGTLGCVLFFGIFGNYAVYLQISEQFNVIQYLNSHGTEATIIEVMHQLPFPTTVIVLFLLSAFLFLATTFDSGSYILAAATQKKVLGEPLKANRLFWAFALCLLPFSLMLVGGERALEVLKTASILASVPLIVIFICMMVSFIITLSKDRIKLETRADKLKEVERRSLRIVQVRENNDEDDNL
>NC_017353.1|WP_002478542.1|397968_398529_-|GbsR/MarR-family-transcriptional-regulator
MVHSQSNEEKLEAAKDLVINSIGQTMDLYGTNRSVGNLFGTMVFEGSMTLDEMREHLQMSKPSMSAGVKKLQEFDLVKQQFTRGSRKQHFIAEKDFFTFFRNFFTKKWEREVDTNMAAIIEAEKIITSVLNDEAIDDEIKQDALNIEQQLKHTKIYCQWLSNLTTALETGEIFDYFPIPNSQENNN
>NC_017353.1|WP_002478543.1|398896_400387_+|betaine-aldehyde-dehydrogenase
MKLVEKLSQRQYIDGKWVESSNKNTREIINPYNQEVVFTVTEGTAEDAEQAILAARRAFEDGEWSLETSEVRGKKVRAIADKITEHRDELAQLETLDTGKTLGESYADMDDIANVFNYFAGLADKDGGEIINTPIPNTESKVVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGVINLILSSGEEVGDTLSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFADADFDLAVDQALNGGYFHAGQVCSAGSRILVHNDIKGDFEKALIDRVGKIKLGNGFDDDTEMGPVISTEHRDKIESYMEIAKKEGATIAIGGKRPDREDLQNGLFFEPTVITNCDTSMRIVQEEVFGPVVTIEGFDSEEEVIELANDSIYGLAGAVFTKDLGKAQRVANKLKLGTVWINDFHPYFAQAPWGGFKQSGIGRELGKEGLEEYLISKHILTNTKPEPINFFSK
>NC_017353.1|WP_002478544.1|400478_402185_+|choline-dehydrogenase
MSENKSYDYVIIGGGSAGSVLGARLSEDKDKNVLVLEAGRSDYPWDLFIQMPAALMFPSGNPFYDWRYQTEEEPHMGRKVDHARGKVLGGSSSINGMIYQRGNPLDYEGWAEPEGMESWDFAHCLPYFKKLEKTFGAAPHDQFRGHQGPIKLKRGPATNPLFKSFFNAGVEAGYHKTEDVNGFRQEGFGPFDSQVHHGRRMSASRAYLRPAMKRKNLTVKTRAFVTELHFEGNKATGVTFKRNGKNHTVNAGEVILSGGAFNTPQLLQLSGIGDADFLKSKGIEPRVHLPGVGENFEDHLEVYIQHECKEPVSLQPSLDVKRMPWIGLQWIFARKGAAASNHFEGGAFVRSNDQVAYPNLMFHFLPIAVRYDGQKAPVAHGYQVHVGPMYSNSRGSLKIKSKDPFEKPSIVFNYLSTKEDEQEWVEAIRVARNILSQKAMDSFNGGEISPGPSVQTDEEILDWVRKDGETALHPSCSAKMGPATDPMAVVDPLTMKVHGMENLRVVDASAMPRTTNGNIHAPVLMLAEKAADIIRGKKPLEPQYVDYYIHGKHDPNDGAMEHNPYYPY
>NC_017353.1|WP_002478545.1|402432_403611_+|amidohydrolase
MGETLVERLKAKEQRMIDIRRYLHEHPELSFHETETPKYIAEFYKDKACDVQTNVGPNGVKVTIDSGKPGKTIAIRADFDALPIQEDTGLSYASQNEGVMHACGHDAHTAYMLVLAETLIEMKDQFSGKVVVIHQPAEEMPPGGAKGMIEDGVLEGVDHVLGIHVMTNMTSGKIYYHEGNTQTGRAYFKLTIHGEGGHGSSPHTAKDAIVAGANFVTTAQNVVSRRLSPFETGVVTIGSFDGKGQFNVIKDTVEIEGDVRALTDATRDTIKYELERIVQGIATSFDVQYDFEFQPDYPALYNDPQFTSYIVETLRQAQLPDVIGVEECEPQPPSEDFAYYAQALPSTFLYSGAAPQQGHAYPHHHPKFNIDESSMLVAAEAVGTIVLDYLQG
>NC_017353.1|WP_002460576.1|403749_404019_+|hypothetical-protein
MTFYDYMQNFVGDQTPLGELAHYLNKDCQFPKHEKTTDNILSYFIDEIELDDEHLETVKRSLSLYEQQTVHFSLVDHIKTEPKENVNED
>NC_017353.1|WP_002478546.1|404008_404458_+|antibiotic-biosynthesis-monooxygenase
MKINEKAPYYALEATSPQTMRIYKNHQHFEYMILESINELIDNGYCMLNHLYVNKGQEGAFEQKFLQRQQHLASVPGFRALRFLRPNEQGQHYVIITQWLNHQSFKNWQQSSAYSQTHQKRGTSQGADVRLVNRKLSYHIGIICERYTS
>NC_017353.1|WP_002478547.1|405094_406687_+|acyl--CoA-ligase
MKQSSLLAPETYNIVSEIEKHVSDQDKNAIIYENGHNDPIAVTYADLMKQANQVGHVLLNHGLKKGDKILIMMPRSISTYRIYIAALKLGIAIIPSSEMLRTKDLQYRISHGEIDAVITMPEFIKEFLNIEEYTSLTKFVVAGHHEAWISIDDERLNQSEELDMAPTSRDDIAILSYTSGTTGNPKAVTHTHGWGFAHMKMAPKHWLSIKEDDLVWATAAPGWQKWVWTPFLSIMGSGATAFVYNGKFNPTRYLELLQNFKINVLCCTPTEYRMMAKLSNLDKYDIHHLHSAVSAGEPLNKEVVNQFEAHFGLTVRDGYGQTESTLLIGFLKDTKPRPGSMGKAIPGSDTTVVDDEGRQVAPGVKGNIGVPLDLPALFKGYYKDEARTKAAHAGKYYITGDLAHIDEDGYFWFEGRSDDIIISSGYTIGPFEVEDALTHHPAVKECAVVASPHEIRGNIVKAFVILNEGYKASDDLVKTLQDFTKKTVAPYKYPRAIEFVEDLPKTNSGKIRRVELRDAERQKYNQQFKQ
>NC_017353.1|WP_002478548.1|406935_409560_+|pyruvate,-phosphate-dikinase
MTKYIYAFDEGQRTMKDLLGGKGANLSEMKRLGLPVPDGFTITTEACIEYLRQHAQLPTEVKTQLVDHLAAFTKRTGKAFSSDTNLLLVSVRSGAKISMPGMMDTILNLGLNDDNVETLASKTGDVRFAYDCYRRLLQMFGEVVYNIPMVAFDTYFEDYKQRHGFENDAAISADGLKDICERFKTIYLEEARKPFPQEPLKQLEEAIEAVFKSWDNDRARVYRDLNEIPHDIGTAVNIQEMVFGNSGDKSGTGVAFTRNPVTGENRLFGEYLLNAQGEDVVAGIRTPQDIQTLYDQMPDVHQAFVKVTKQLEAHYKDMQDIEFTIENGKLYLLQTRNGKRTAKAAVKIAVDLANEGLITQQEAMRKVDVKAIDQLLHPNFDDKALAEATTISTLGLPASPGAATGQIVFSAEDAKVQADSGKKVILMRPETSPEDIEGMVASEAIITTHGGMTSHAAVVARGMGKCCVTGCSDLEINTSAKTVYYPDGELHEGDTISVDGSKGDIYFGEIKTVNAEHSEDFDQFMTWAEDTARLSVRMNAETPQDIEAGYQFGAKGIGLVRTEHMFFGAERLVEMRRFILASSYDERVDALNAIEKYQVEDFEAIFRLSGERPTIVRLLDPPLHEFLPNSAEDIQHVAQQLNISEDILKKRIVDLHEVNPMLGHRGCRLAVTYPELYEMQVEAIISSVIRLKKEGINCKPEIMIPLVSTVEEFTVLKEDLVETIHKLEQQAGEKVDYLVGTMIETPRACLIAGELAEHCDFFSFGTNDLTQLAYGFSRDDAGKFINVYTERNILKLDPFQTLDKDGVGRLIQIAVEQAKRVNSNIKIGVCGELGGDAKSIHQFNKLSIDYVSCSPFRVPGAIIATAQSQVEESE
>NC_017353.1|WP_002478549.1|409564_410380_+|kinase/pyrophosphorylase
MKQHVLKLFIVSDSIGETAQRMIQATLTQFPDLTQVEIKKFPYIKNEEEFLNVLNLAHEQGAIVATTLVNPSFNSLGHRFAEEKALPYVDYMSELISIVQEQTQTEPLLESGALRKLNDEYFKRIKAIEYSVKYDDGKHFSDIGEADALIVGVSRTSKTPLSMYLANKGYKIANIPLVPEVAIPESVFKQKGLKVFGLTASPQYIANIRKNRVETLGLTQESQYNSLERIKKELSYAEEVFKKLNATVINTEYKSIEESAFYIEKFLQPKY

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017353_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017353_3

577536-577617

Orphan

Consensus_repeat	Method
GCAAGTTGGGGTGGGGCCCCAACAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017353_3

>merge|NC_017353|3|577536-577617|CRISPRCasFinder
GCAAGTTGGGGTGGGGCCCCAACAAAAAGAAATGCGACAAGCATTTCCGCGAACAACGCAAGTTGGGGTGGGCCCCAACAAA

>NC_017353|3|3|577536-577617|CRISPRCasFinder
GCAAGTTGGGGTGGGGCCCCAACAAA	AAGAAATGCGACAAGCATTTCCGCGAACAA
CGCAAGTTGGGGTGGGCCCCAACAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017353.1\|WP_002460367.1\|582207_583161_-\|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|225762
NC_017353.1\|WP_002478654.1\|572165_573704_-\|exopolyphosphatase	unknown	unknown	gnl\|CDD\|274735
NC_017353.1\|WP_002478659.1\|583407_584931_+\|DNA-binding-protein	unknown	unknown	unknown
NC_017353.1\|WP_044019726.1\|565033_566386_+\|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl\|CDD\|273568
NC_017353.1\|WP_002478661.1\|586737_588315_-\|FMN-binding-glutamate-synthase-family-protein	unknown	unknown	gnl\|CDD\|223147
NC_017353.1\|WP_002478657.1\|577863_579144_-\|O-acetylhomoserine-aminocarboxypropyltransferase/cysteine-synthase	unknown	unknown	gnl\|CDD\|225428
NC_017353.1\|WP_002478655.1\|575795_576872_-\|M42-family-metallopeptidase	unknown	unknown	gnl\|CDD\|349906
NC_017353.1\|WP_002460370.1\|580500_581307_-\|phosphonate-ABC-transporter,-permease-protein-PhnE	unknown	unknown	gnl\|CDD\|273441
NC_017353.1\|WP_002478652.1\|568231_569467_+\|acetylornithine-deacetylase	unknown	unknown	gnl\|CDD\|181495
NC_017353.1\|WP_002478656.1\|577037_577493_+\|DUF1307-domain-containing-protein	unknown	unknown	gnl\|CDD\|227145
NC_017353.1\|WP_002460385.1\|566569_566761_+\|hypothetical-protein	unknown	unknown	unknown
NC_017353.1\|WP_002478658.1\|579673_580504_-\|phosphonate-ABC-transporter,-permease-protein-PhnE	unknown	unknown	gnl\|CDD\|273441
NC_017353.1\|WP_002460360.1\|589417_590197_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|224185
NC_017353.1\|WP_002460368.1\|581308_582082_-\|phosphonate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|131368
NC_017353.1\|WP_002478653.1\|569907_572073_-\|RNA-degradosome-polyphosphate-kinase	unknown	unknown	gnl\|CDD\|235469
NC_017353.1\|WP_002478660.1\|584947_586486_+\|bifunctional-metallophosphatase/5'-nucleotidase	unknown	unknown	gnl\|CDD\|223808
NC_017353.1\|WP_002460377.1\|574013_575561_-\|AbgT-family-transporter	unknown	unknown	gnl\|CDD\|367668
NC_017353.1\|WP_002478662.1\|588630_589395_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|224185
NC_017353.1\|WP_002478650.1\|566915_567182_-\|DUF1413-domain-containing-protein	unknown	unknown	gnl\|CDD\|377790
NC_017353.1\|WP_002478651.1\|567336_568032_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|226674

Protein	Function_ID	Function_description	E-value
NC_017353.1\|WP_002478654.1\|572165_573704_-\|exopolyphosphatase	gnl\|CDD\|274735	TIGR03706, exo_poly_only, exopolyphosphatase. It appears that a single enzyme may act as both exopolyphosphatase (Ppx) and guanosine pentaphosphate phosphohydrolase (GppA) in a number of species. Members of the seed alignment use to define this exception-level model are encoded adjacent to a polyphosphate kinase 1 gene, and the trusted cutoff is set high enough (425) that no genome has a second hit. Therefore all members may be presumed to at least share exopolyphospatase activity, and may lack GppA activity. GppA acts in the stringent response. [Central intermediary metabolism, Phosphorus compounds].	8.31845e-122
NC_017353.1\|WP_002478660.1\|584947_586486_+\|bifunctional-metallophosphatase/5'-nucleotidase	gnl\|CDD\|223808	COG0737, UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism].	1.22109e-92
NC_017353.1\|WP_044019726.1\|565033_566386_+\|dihydrolipoyl-dehydrogenase	gnl\|CDD\|273568	TIGR01350, Dihydrolipoyl_dehydrogenase, dihydrolipoamide dehydrogenase. This model describes dihydrolipoamide dehydrogenase, a flavoprotein that acts in a number of ways. It is the E3 component of dehydrogenase complexes for pyruvate, 2-oxoglutarate, 2-oxoisovalerate, and acetoin. It can also serve as the L protein of the glycine cleavage system. This family includes a few members known to have distinct functions (ferric leghemoglobin reductase and NADH:ferredoxin oxidoreductase) but that may be predicted by homology to act as dihydrolipoamide dehydrogenase as well. The motif GGXCXXXGCXP near the N-terminus contains a redox-active disulfide.	3.19038e-144
NC_017353.1\|WP_002478661.1\|586737_588315_-\|FMN-binding-glutamate-synthase-family-protein	gnl\|CDD\|223147	COG0069, GltB, Glutamate synthase domain 2 [Amino acid transport and metabolism].	1.28723e-151
NC_017353.1\|WP_002478657.1\|577863_579144_-\|O-acetylhomoserine-aminocarboxypropyltransferase/cysteine-synthase	gnl\|CDD\|225428	COG2873, MET17, O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism].	0
NC_017353.1\|WP_002478655.1\|575795_576872_-\|M42-family-metallopeptidase	gnl\|CDD\|349906	cd05656, M42_Frv, M42 Peptidase, endoglucanases. Peptidase M42 family, Frv (Frv Operon Protein; Endo-1 4-Beta-Glucanase; Cellulase Protein; Endoglucanase; Endo-1 4-Beta-Glucanase Homolog; Glucanase; EC. 3.2.1.4) subfamily. Frv is a co-catalytic metallopeptidase, found in archaea and bacteria, including Pyrococcus horikoshii tetrahedral shaped phTET1 (DAPPh1; FrvX; PhDAP aminopeptidase; PhTET aminopeptidase; deblocking aminopeptidase), phTET2 (DAPPh2) and phTET3 (DAPPh3), Haloarcula marismortui TET (HmTET) as well as Bacillus subtilis YsdC. All of these exhibit aminopeptidase and deblocking activities. The HmTET is a broad substrate aminopeptidase capable of degrading large peptides. PhTET2, which shares 24% identity with HmTET, is a cobalt-activated peptidase and possibly a deblocking aminopeptidase, assembled as a 12-subunit tetrahedral dodecamer, while PhTET1 can be alternatively assembled as a tetrahedral dodecamer or as an octahedral tetracosameric structure. The active site in such a self-compartmentalized complex is located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers. PhTET2 cleaves polypeptides by a nonprocessive mechanism, preferring N-terminal hydrophobic or uncharged polar amino acids. Streptococcus pneumoniae PepA (SpPepA) also forms dodecamer with tetrahedral architecture, and exhibits selective substrate specificity to acidic amino acids with the preference to glutamic acid, with the substrate binding S1 pocket containing an Arg allows electrostatic interactions with the N-terminal acidic residue in the substrate. The YsdC gene is conserved in a number of thermophiles, archaea and pathogenic bacterial species; the closest structural homolog is Thermotoga maritima FrwX (34% identity), which is annotated as either a cellulase or an endoglucanase, and is possibly involved in polysaccharide biosynthesis or degradation.	3.65164e-166
NC_017353.1\|WP_002460370.1\|580500_581307_-\|phosphonate-ABC-transporter,-permease-protein-PhnE	gnl\|CDD\|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	3.59558e-99
NC_017353.1\|WP_002478652.1\|568231_569467_+\|acetylornithine-deacetylase	gnl\|CDD\|181495	PRK08596, PRK08596, acetylornithine deacetylase; Validated.	0
NC_017353.1\|WP_002478656.1\|577037_577493_+\|DUF1307-domain-containing-protein	gnl\|CDD\|227145	COG4808, COG4808, Uncharacterized protein conserved in bacteria [Function unknown].	5.87133e-23
NC_017353.1\|WP_002460367.1\|582207_583161_-\|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|225762	COG3221, PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component [Inorganic ion transport and metabolism].	6.3779e-94
NC_017353.1\|WP_002478658.1\|579673_580504_-\|phosphonate-ABC-transporter,-permease-protein-PhnE	gnl\|CDD\|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	2.43826e-83
NC_017353.1\|WP_002460360.1\|589417_590197_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|224185	COG1266, COG1266, Predicted metal-dependent membrane protease [General function prediction only].	1.26376e-08
NC_017353.1\|WP_002460368.1\|581308_582082_-\|phosphonate-ABC-transporter-ATP-binding-protein	gnl\|CDD\|131368	TIGR02315, Phosphonates_import_ATP-binding_protein_PhnC, phosphonate ABC transporter, ATP-binding protein. Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions].	2.07624e-143
NC_017353.1\|WP_002478653.1\|569907_572073_-\|RNA-degradosome-polyphosphate-kinase	gnl\|CDD\|235469	PRK05443, PRK05443, polyphosphate kinase; Provisional.	0
NC_017353.1\|WP_002460377.1\|574013_575561_-\|AbgT-family-transporter	gnl\|CDD\|367668	pfam03806, ABG_transport, AbgT putative transporter family.	0
NC_017353.1\|WP_002478662.1\|588630_589395_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|224185	COG1266, COG1266, Predicted metal-dependent membrane protease [General function prediction only].	0.00491327
NC_017353.1\|WP_002478650.1\|566915_567182_-\|DUF1413-domain-containing-protein	gnl\|CDD\|377790	pfam07205, DUF1413, Domain of unknown function (DUF1413). This family consists of several hypothetical bacterial proteins which seem to be specific to firmicute species. Members of this family are typically around 100 residues in length. The function of this family is unknown.	1.07719e-08
NC_017353.1\|WP_002478651.1\|567336_568032_+\|SDR-family-oxidoreductase	gnl\|CDD\|226674	COG4221, COG4221, Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only].	3.22398e-84

>NC_017353.1|WP_002478656.1|577037_577493_+|DUF1307-domain-containing-protein
MKKFIAMIAIVVITIVTLSACDKERTKTYEGDIDGKHVITSLTYKNNKVISQSTISTLKYDDMGLSEKEGKALFKKHKALENAKGVDYRLTSERDKIDEKVDIDYNKADIQKIKRNFDLFSYDKNNHKVNMENSVKYLKKLGFEEKSKMTK
>NC_017353.1|WP_002478655.1|575795_576872_-|M42-family-metallopeptidase
MKASIELLKTLTDVNGIAGQEMQVKETMRDYLNPISDSIIEDHLGGIFGKREATYGTKSIMLAGHLDEIGFIVTKIDNEGFIKFQPIGGWWSQVMLSQKVTITTDQGQEIRGIIGSKPPHVLEAEERKKAVDIKDMFIDIGARSREDVEQHGIEVGNMITPYSEFETLANSKYLTAKAFDNRYGCAVAVEVLKNLKDENLGINLYAGATVQEEVGLRGAKVAAQTIKPDLAIAVDVCVPYDIPGMSGQTSETALGNGPVVIMMDASSIAHQGLRQHIKEVAKKHYISVQWDTTPGGGTDAGSIHVANEGIPTITIGVALRYMHSNVSVLHTDDYENSVRLITEIVRSLNDETYQQIVW
>NC_017353.1|WP_002460377.1|574013_575561_-|AbgT-family-transporter
MPSSVKRKEKASFITRFLNGVEWVGNKLPDPAVLFFMMCVLLAVMTWVISWFNVSVKHPGNGHTIHIKSIISTDGIAMIMNDAIKNFSEFPALGLVLAVMIGIGAAEKSGYFDKLLISVVNHASKKLILPTIIFIGIMGSIAGDATTVILPPLAAMLFIKIGYHPIAGLAMAYASSLGGFGANLIIGMQDALVYAFTNPATKIVTDKVNTNVAMNWYFIAASVFMLIPTLYFTTTKLVIPHLGKYDDSKAELDDTDQPSSTVTPIEQRALRWANISFIVLVVALIICAIPEGSWLRNPKTGSLIDNSPLINGVGLVILVIFLIPGVIYGVLSKQIKSTKDLGKMISDSLATMSSFILIVFFAAQLLAFLKWSNLGVIVAVKGANLLQGQHGIVLIIGILILSGLVNMVIGSASAKWGILAPIFVPMMLLIGFHPAFTQMIYRVGDSITNPITPMMPYMPLLLTYAQKYDKNMKLGSLLSSLMPYTIVLSIVWTLFLIIWYLLGIPVGPGGPIKAN
>NC_017353.1|WP_002478654.1|572165_573704_-|exopolyphosphatase
MEERIGLIDIGSNTIRLVIFKFSKTAGLNEILNIKTPARLSQYLTSKKEMSKDGIKVLIEALKSFKKVAQEFNVTELHPIATAAIRQSKNKNAIIKQVKKELNIDMKIIPELDEAYYGFYAITHTTEIANGVSVDIGGGSTEVTLFKDKELVESHSFPFGVVTLTRMFFENKAHNNKSAIKDMEKFISSQFDELSWLQDKKVALVGVGGSARNVARIHQSEHSYPIGGVHNYTMSDNDIEEVLDIIRKSDRDDLTNLDGLSRDRVDIILPAVCVFKALYKKVNATQFTFSRNGLREGYIIKQIRDRYTDVFDKYNVRKEAIHFLANEYQIEESSSASRLKLAKSLLSQIMQYSEFNLSDKEQRLFEEGAYIYYLGSFIDSDSSSPHSYYIIANSMINGYTHKDRVKLALLASFKNKSLLKFYCTETNWFGNKEIDTIQILGGIIKFVNALNISHTSFVEDVSLKPLKKAEEDFELIVYHKGEPIAEKYQAMRQKKHIEKVLKGKVAITFTKY
>NC_017353.1|WP_002478653.1|569907_572073_-|RNA-degradosome-polyphosphate-kinase
MQNQLGENNINLPQYYNNRELSWLDFNYRVLQEAYDDNNPLLEKLNFISIFSSNLDEFFMVRVAGLKDQVKMGYDKPENKAQMTPQEQVDAIQEKNTTYVDKQYERYNELIEELRQYDIEMSQPEQLSNQLLTRLEQEFKTTILPTLTPLGIDAYHPFPKLNNKSLNIFVDIDTEDAINSAIVQIPSLIPRFITLNEGTKQYVLMVEDVITYFINYLFTGYEVLNTFTFRITRNADLTIHEDGAEDLLIEIERFLKERKSGSAVRLEVDGRTANSDDIPWLIDTLEVENNDVYFVNGPLDLTFLFGLVDHLSHKLKFLTYEQYTPQVPRSLGTNNIYELALKRDIFFHHPYESFQPIVDFIREAADDPDTIAIKQTLYRVSKDSPIIKSLKEAAEKGKQVTVLVELKARFDEENNVHWARMLEDAGCHVIYGMTHLKTHSKIALVVKRTHGTLTSFVHLGTGNYNDKTAKLYTDMGIITTNKEIAEDAINFFNYLSGYSVKPVYNKLIVAPFDIRDVFIDRIDKEIKSHHEHGNGHIIMKMNSLTDKAIIKKLFEASQAGVKIQLIIRGICCLKPGIPGISENIEVVSIVGRLLEHSRIYYFYNNGDQRIYLSSADVMTRNMIKRVEILFPVEDNDIAKRLLDYMNLQLSDNQKGRYQDQYGQYHYIKNDMSPLNSQAYLMQKAIKYGKQLKKLASQPSGVPVVSKRGAGWVKKLRDTFKR
>NC_017353.1|WP_002478652.1|568231_569467_+|acetylornithine-deacetylase
MEQRLFDLLELLVKYNTESPPGRNTNPLQDDIQRLLEDLGFTIQREVLYPNDSIIVATLKGEDPTAPKLILNGHVDVASVDDDREWNYPPFELTHVNDWLYGRGVSDMKGGMAALFYVLERLHQEGRLPQGDIIVHSVVGEEVGEAGTKRACEIGPKADLALVLDTSDNMALGQGGVITGWITVKSKHTIHDGARHQTIHAGGGLFGASAIEKMMKVIQALNELERHWAVMKSSPGMPPGANTINPAVIEGGRHPAFIADECRLWITVHYLPNECYEDVIAEIETYLNQVAAADIWLKDHPLSFEWGGASMIEDKGEIFPSFEIPTTHPGFKALQQAHELVHHKPLEHGMSTTVTDGGWTAHFGIPTILYGPGSLTEAHSVDEKITATELQTYSEVLYQYLKQWYQHPVKN
>NC_017353.1|WP_002478651.1|567336_568032_+|SDR-family-oxidoreductase
MDNIVGRVAVITGASSGIGKEIAKAMHSMGFRVVLAGRNRKRLNQVAMHMRKYERLIVEIDMTQRQEVEALIAKAIEYFGRVDILVNSAGLSLSSQITSHQVEDWDAMIDTNLKGTLYAINAVLPHFQQYKEGHIINLASISAEEVTKDSTVYSATKAAVQMISRGLEKDLARTGIKVTSILPGMVDTPMTEQSDFGGRKKLETYDIAESIRYAITQPPHVNVNQITIRPV
>NC_017353.1|WP_002478650.1|566915_567182_-|DUF1413-domain-containing-protein
MTYHDRVMKLRAEKKRMGFSFRFEDLFSEEELLNMTVAQRKTAEKKFIREIDNMHDVRMPFSSQDGFKNKLYNLEYQYNEVKKNFKVV
>NC_017353.1|WP_002460385.1|566569_566761_+|hypothetical-protein
MRKVIEQVIFSNESSYKIHVHTGVNQGLIGDIRDGYITIDSMPYIDAERLYQYGLEHKEVVPS
>NC_017353.1|WP_044019726.1|565033_566386_+|dihydrolipoyl-dehydrogenase
MVEQFDLIVVGAGPGGYVASIRAAQLGMKVAVIEKDRVGGTCFNVGCIQSKLLIEHGKRVYEMNQAKDWGIFANHIELDINKMNHRKDEVVDEIIGNVHHLFDENHVNYIQGEAVVHSDLSVEVNGRVLHANDIVLATGSSPFVPPIEDVDKIDYETTDSFFKHSTLPEQLTIVGGGVIATELASAMTDLSVHVTILESGDNILRSEDKDVQASIRKLLDHQGVKIVTHARVNKVDTDAVYLENGSQLPYGTLLFATGRRPNLQAFESLNLTMEDKTIKVNEFNETSVPHVYAIGDLVAGYQLAHTASAHGAVVAEKIAGLNPDPVKQEDIPRCIYTRVESASIGLSEAQAIAQGYDVKVTQSNFKEAPKALIKGETNGVIKMVIDKATHHILGIFAAGPNATDVVGQMSAMRAAHGQLEDLAAMIQPHPALSETIGETANAYFNKAIHQ
>NC_017353.1|WP_002478657.1|577863_579144_-|O-acetylhomoserine-aminocarboxypropyltransferase/cysteine-synthase
MTNQNWHFETQTIHAGQEIDDFSKSRAVPIYQTSSYVFDNTQHAQDLFALAQPGNIYTRIMNPTQNVFEERVAALEGGIGALATSSGQAAITLALLNIVNTGDEIVASSNLYGGSYNLLNVTFKKLGITVHFVDPDHPENFAAQINDNTKAIYAETMGNPKIDVLDITAVADVAHQHGIPLIIDNTFASPYLCRPFEFGADIVIHSATKFIGGHGTSIGGIIVDSGKFNWDNGKFPGLVEPDESYHGVSYTKDVGEAAYITKARVQLLRDLGSAVSPYNVHEFLIGLETLHLRMERHSANALKVAQFLDQHPKVTWVNYPGLVNNKYHALAEKYLPKGQGAILTFGVDGSVEDISRFVDALDLFSLLANVGDSKSLVIHPASTTHLQLSEEEQRKSGVLPEMVRLSIGTENADDIINDLAQALETV
>NC_017353.1|WP_002478658.1|579673_580504_-|phosphonate-ABC-transporter,-permease-protein-PhnE
MTHEPQTFQSPKYNLSTKRQKQRVIKRWVIAIVVALIVIWGFAGMPALELKSKSVEILKAIFSGLFHPDLGYIYIPEGEDLLRGLLETFAIAVIGTFIAAIICIPFAFLGANNLVKLRPVTGTTKFILSVIRVFPEIVMALIFIKAVGPGSFSGVLALGIHSVGMLGKLFVEDIESLDFTSVESLKASGANKTKTLVFAVIPQILPSFLSLILYRFELNLRSASILGLIGAGGIGTPLIFALQTRSWDRVGIILIGLVIMVAIVDLISGAIRKRIV
>NC_017353.1|WP_002460370.1|580500_581307_-|phosphonate-ABC-transporter,-permease-protein-PhnE
MTSPATSTNKYDKYLNKKLSLKTSFSILIVAVLVIWSFVYTGFSFSDLMVGVPQIGDFFKQMFPPEWSYLKAIWQPMLDTIRMAIVGTFLGAIVSVPIALICASNIIRTKWITIPARFILNIVRTIPDLLLAAIFVAVFGIGQIPGVLALFILTICVIAKLLYEAIETIEPGPMEAMTAVGANKTKWIVFGVVPQIISTYFSYVLFAFEINIRASAVLGLVGAGGIGLFYDSTLGLFQYPRTAMIILFTLVIVVIIDYVSSKVREQLA
>NC_017353.1|WP_002460368.1|581308_582082_-|phosphonate-ABC-transporter-ATP-binding-protein
MSQIEFKDVSKVYPNGHVGLKDINLNIEKGDFAVIVGLSGAGKSTLLRSVNRLHDVTSGDITIEGKSITQAKGKSLLLMRRNIGMIFQHFNLVKRSTVLRNVLSGRVGYHPTWKMILGLFPKEDKIKAMDALERVNILDKFDQRSDELSGGQQQRISIARALAQEPSIILADEPVASLDPLTTKQVMDDLKKINEELGITILINLHFVDLALEYGTRIIGLRDGELVYDGPAEEATEEVFNEIYGRQLKADEKLGVN
>NC_017353.1|WP_002460367.1|582207_583161_-|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein
MKHVKYLLLLVLSVVIFAAACGGNSSLDNNSKSSNSESGKGNYKPKELTVQFVPSQNADKLEAKAKPLEKLLSKELDIPVKVSVSTNYNTIVEAMKSKKVDVGFLPPTAYTLAHDQKAADLLLQAQRFGVNKDGSPTKKLVKDYKSEILVKKDSGIKSLKDLKGKKIALQDVTSTAGYTFPIATLKEKAGIDATKDMKIVNMKGHDQSIISLLNGDVDAAAVFQDARNVVKKDQPNVFKDTKILELTKPIPNDTISVRPDMDKDFQKKLKKAFKDISKTKEGHKIISEVYSHEGYTDAKDSDFDIVREYEKKVKDMQ
>NC_017353.1|WP_002478659.1|583407_584931_+|DNA-binding-protein
MKMIKVVSSTIVASALALSMFPSTQAAETNTASRTVLFDNSHGQTAGAADWVIDGGFSDYADSMKKQGFAVKSLDGEANISQESLKNSDILVIPEANIPFKTTEQQAIVNFVNHGGSIIFISDHYNADRNLNRIDSSEAMNGYRRGAYADMTKDMDQGEKQSKAMAGVSSSDWLAQNFGVRFRYNALGDLNTSNLVSSDESFGITKGVKSVSMHAGSTLAITDPKKAKGIVYTPDHLGNNAKWSHAVDQGVYNGGGKAEGAYIAIAKVGKGKAAFIGDSSLVEDSSPKYLREDTGKTKKTYDGFKEEDNAQLLNNLTSWLSKKEATPNLAKSGVKLDKATVLHDFEQPQNSTEPQKEPWSQPPEGYHWYDRSTFAPGSYGSTKSTKDDGDKQPGDQPAVQNVAFAIPKDVQANTPFNITINLSQLPANQSLDNLKLGIYQDGGKQIGQFSTDGKSYSNIGYGSLPTIKVNKDGTASVTISAKVTESLKGANIRLKQGDKTLKTEKLK
>NC_017353.1|WP_002478660.1|584947_586486_+|bifunctional-metallophosphatase/5'-nucleotidase
MTQLAFYILSDIHGYIFPTDFKQTKGYKPMGLLLANHIIEQDRQRYDASFKIDNGDFLQGSPFCHYLATHIHSSKPLTDIYNRIGFDFGTLGNHEFNYGLNYLTQSINRLNYPILCANILKDNKSLTEQGIMYIKKQGYNIGIIGLTTQYIPHWERPEYIQHLTFNSAVQTLEDILPQVREQADIVVVSYHGGFERNIDTYQPTEVLTGENEASEILQRFGSDIDVLITGHQHREIAAIKHDTVILQPGTRATQIGKVTLTFNDRRQLVQRTSELLPVHDDSAFKLTDKDSQLMSDVDTWLDTPIAEIQQNMIVDEPFTARIAPHPFINVLLHALLQTSGAQIASTALFDSATGFDKTITMRDIINNYPFPNTFKVLEMTGKGIREALEQSARYFDLTDSGDVGINDTFLNPKPQHYNYDIFGGVSYNIKVSEPMGHRVHDIKVEGQPLVEDKIYTVCVNNYRAVGGGDYNMFAEAKVVKDIQVEGAQLLIDYLTHHNLNNMPQVVDFKVEI
>NC_017353.1|WP_002478661.1|586737_588315_-|FMN-binding-glutamate-synthase-family-protein
MILTTMQFIVNVIIVSCLLFVVLLGLWLLFKDKHQKQHSVLRNFPLLGRIRYFSEKIGPEMRQYLYANDTEGKPFSRVDYKNIVIAGKYNSRMTSFGTLKHYEHGFYIQNAMFPLQSTELVIDNQHMISTFIYQVDNERLFKRDEHRKPADIKPFQLDDQHAVVIGNDLAHPFIVKRLVGQSGMSYGALGQRAITALSQGLARAGTWMNTGEGGLSDYHLSGGGDIIFQIGPGLFGVRDQEGNFSKDEFVKLVNQSAIKAFELKLAQGAKTRGGHMEGNKVTEEIAQIRNVKPFQTINSPNRFNFISNAAELITFVDELKQLGQKPVGFKIVVSHVDEIEILVKEMIRLDKYPSFITVDGGEGGTGATFQELQDGVGLPLFTALPIVSGMLERYGIRDKIKIFASGKLITPDKIAIALGLGADLVNIARGMMISVGCIMSQQCHLNTCPVGVATTDPKKEKALIVEEKTFRVTNYITSLHEGLYNIAAAVGVNNPTNITAQHIIHQQQNGTLQSIDTYKLKLLEP
>NC_017353.1|WP_002478662.1|588630_589395_+|CPBP-family-intramembrane-metalloprotease
MQTLNTYNTRQPIDAHVKKRLFWVIPVYVFLKVLMPIIIVFGVYGIWAVLTQDKPTQVIYPIVLTLSFIVAEIVTLKCFFFLYQQKLRTIYQRLSSDIKPMLWPIVIVSCLTLLAYYGGQCIAHHLNQPWGFQHSQSEQYLSGMFTHPHALPFVWVSMVVLRPLVEELIFRHLFIHELAKCIPMVVAMIFSIIADVVAHSYHYHSVLEIGIYSLIPIGAVIIYRWSQQNLLAAYVYHSMTQCIIFLVLSYQSYL
>NC_017353.1|WP_002460360.1|589417_590197_+|CPBP-family-intramembrane-metalloprotease
MNHRMTKNNRISSMTYHQNPWRQPQMVKRDFLLILVYVLGNMYLPFILADAINWLSFTLLHRPSGLTYTSQLYALLAQLSVVLIFWALHYRALLNTAIARVKQLQRYIYLMIIVLLVMYVANIVYANVMQFLPEHWQFHDTQNEQEIRKLFSNIKVWPLLFLNIVIITPIVEELLFRHLLIHELGKKLSYPVMSIISILLFAGIHVTDATSPFEIGPYLIMATSFVVAYNMSGRNLAVTIALHSFNNLLSFILTLLQFL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017353_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017353_4

609844-609924

Orphan

Consensus_repeat	Method
ACGGATAACGCAAGCTGGGGTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017353_4

>merge|NC_017353|4|609844-609924|CRISPRCasFinder
ACGGATAACGCAAGCTGGGGTGGGGGCCCCAGCAAAAAGAAATGCAAAACGCATTTCTACGGACAACGCAAGCTGGGGTGG

>NC_017353|4|4|609844-609924|CRISPRCasFinder
ACGGATAACGCAAGCTGGGGTGG	GGGCCCCAGCAAAAAGAAATGCAAAACGCATTTCT
ACGGACAACGCAAGCTGGGGTGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017353.1\|WP_037553687.1\|606527_607163_+\|DUF443-family-protein	unknown	unknown	gnl\|CDD\|335700
NC_017353.1\|WP_002478684.1\|622031_622976_+\|hypothetical-protein	unknown	unknown	unknown
NC_017353.1\|WP_002478680.1\|614591_615524_+\|2-dehydropantoate-2-reductase	unknown	unknown	gnl\|CDD\|235821
NC_017353.1\|WP_002478677.1\|608517_609219_-\|antiholin-like-protein-LrgB	unknown	unknown	gnl\|CDD\|179810
NC_017353.1\|WP_002478672.1\|604015_604381_+\|DUF3958-family-protein	unknown	unknown	unknown
NC_017353.1\|WP_002478671.1\|603727_604000_+\|TIGR04197-family-type-VII-secretion-effector	unknown	unknown	gnl\|CDD\|275045
NC_017353.1\|WP_002460335.1\|610190_610952_-\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|184495
NC_017353.1\|WP_002460323.1\|619816_621643_+\|APC-family-permease	unknown	unknown	gnl\|CDD\|372624
NC_017353.1\|WP_012990737.1\|618023_619535_-\|serine-hydrolase-FLP	unknown	unknown	gnl\|CDD\|365903
NC_017353.1\|WP_002478673.1\|604370_605828_+\|transposase	unknown	unknown	gnl\|CDD\|368093
NC_017353.1\|WP_002478674.1\|605830_606457_+\|DUF443-family-protein	unknown	unknown	gnl\|CDD\|335700
NC_017353.1\|WP_002460346.1\|602737_603418_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224095
NC_017353.1\|WP_002478678.1\|609218_609680_-\|antiholin-like-murein-hydrolase-modulator-LrgA	unknown	unknown	gnl\|CDD\|235222
NC_017353.1\|WP_014533224.1\|617090_617912_-\|membrane-protein-insertase-YidC	unknown	unknown	gnl\|CDD\|179310
NC_017353.1\|WP_002478676.1\|607604_608246_+\|DUF443-family-protein	unknown	unknown	gnl\|CDD\|335700
NC_017353.1\|WP_002460342.1\|607159_607471_+\|DUF4176-domain-containing-protein	unknown	unknown	gnl\|CDD\|226892
NC_017353.1\|WP_002460334.1\|610952_612707_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225814
NC_017353.1\|WP_002478681.1\|615705_615972_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|273701
NC_017353.1\|WP_002478679.1\|613014_614409_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340879
NC_017353.1\|WP_002478682.1\|616175_617027_+\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223528

Protein	Function_ID	Function_description	E-value
NC_017353.1\|WP_037553687.1\|606527_607163_+\|DUF443-family-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	6.326e-40
NC_017353.1\|WP_002478680.1\|614591_615524_+\|2-dehydropantoate-2-reductase	gnl\|CDD\|235821	PRK06522, PRK06522, 2-dehydropantoate 2-reductase; Reviewed.	8.83675e-117
NC_017353.1\|WP_002478677.1\|608517_609219_-\|antiholin-like-protein-LrgB	gnl\|CDD\|179810	PRK04288, PRK04288, antiholin-like protein LrgB; Provisional.	1.31693e-130
NC_017353.1\|WP_002478671.1\|603727_604000_+\|TIGR04197-family-type-VII-secretion-effector	gnl\|CDD\|275045	TIGR04197, conserved_hypothetical_protein, type VII secretion effector, SACOL2603 family. Members of this protein family are similar in length and sequence (although remotely) to the WXG100 family of type VII secretion system (T7SS) targets, described by family TIGR03930. Phylogenetic profiling shows that members of this family are similarly restricted to species with T7SS, marking this family as a related set of T7SS effectors. Members include SACOL2603 from Staphylococcus aureus subsp. aureus COL. Oddly, members of family pfam10824 (DUF2580), which appears also to be related, seem not to be tied to T7SS.	1.02519e-18
NC_017353.1\|WP_002460335.1\|610190_610952_-\|DNA-binding-response-regulator	gnl\|CDD\|184495	PRK14084, PRK14084, DNA-binding response regulator.	1.00235e-149
NC_017353.1\|WP_002460323.1\|619816_621643_+\|APC-family-permease	gnl\|CDD\|372624	pfam13520, AA_permease_2, Amino acid permease.	5.1718e-32
NC_017353.1\|WP_012990737.1\|618023_619535_-\|serine-hydrolase-FLP	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	6.70581e-68
NC_017353.1\|WP_002478673.1\|604370_605828_+\|transposase	gnl\|CDD\|368093	pfam04740, LXG, LXG domain of WXG superfamily. This domain is present is the N-terminal region of a group of polymorphic toxin proteins in bacteria. It is predicted to use Type VII secretion pathway to mediate export of bacterial toxins.	1.39116e-07
NC_017353.1\|WP_002478674.1\|605830_606457_+\|DUF443-family-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	2.09616e-44
NC_017353.1\|WP_002460346.1\|602737_603418_+\|ABC-transporter-permease	gnl\|CDD\|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	1.98074e-72
NC_017353.1\|WP_002478678.1\|609218_609680_-\|antiholin-like-murein-hydrolase-modulator-LrgA	gnl\|CDD\|235222	PRK04125, PRK04125, antiholin-like protein LrgA.	6.29535e-71
NC_017353.1\|WP_014533224.1\|617090_617912_-\|membrane-protein-insertase-YidC	gnl\|CDD\|179310	PRK01622, PRK01622, membrane protein insertase YidC.	1.0147e-49
NC_017353.1\|WP_002478676.1\|607604_608246_+\|DUF443-family-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	2.31921e-44
NC_017353.1\|WP_002460342.1\|607159_607471_+\|DUF4176-domain-containing-protein	gnl\|CDD\|226892	COG4495, COG4495, Uncharacterized protein conserved in bacteria [Function unknown].	3.23782e-28
NC_017353.1\|WP_002460334.1\|610952_612707_-\|sensor-histidine-kinase	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	0
NC_017353.1\|WP_002478681.1\|615705_615972_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|273701	TIGR01575, rimI, ribosomal-protein-alanine acetyltransferase. Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR\|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification].	6.16496e-06
NC_017353.1\|WP_002478679.1\|613014_614409_+\|MFS-transporter	gnl\|CDD\|340879	cd17321, MFS_MMR_MDR_like, Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial, fungal, and archaeal multidrug resistance (MDR) transporters including several proteins from Bacilli such as methylenomycin A resistance protein (also called MMR peptide), tetracycline resistance protein (TetB), and lincomycin resistance protein LmrB, as well as fungal proteins such as vacuolar basic amino acid transporters, which are involved in the transport into vacuoles of the basic amino acids histidine, lysine, and arginine in Saccharomyces cerevisiae, and aminotriazole/azole resistance proteins. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. For example, MMR confers resistance to the epoxide antibiotic methylenomycin while TetB resistance to tetracycline by an active tetracycline efflux. MMR-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.38074e-39
NC_017353.1\|WP_002478682.1\|616175_617027_+\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|223528	COG0451, WcaG, Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	5.38244e-30

>NC_017353.1|WP_002478678.1|609218_609680_-|antiholin-like-murein-hydrolase-modulator-LrgA
MANENVNKAKAHSQSVVSKTYNFFQQALTIAVILLISKIIESFIPFPMPASVIGLVLLFIALCTGIVKLGQVESVGTALTNNISFLFVPAGVSVINSLPILSKNPILIILLIIISTLLLLVCVGFASQFLVTKSLFPTAEQNEKSRHVEGDNH
>NC_017353.1|WP_002478677.1|608517_609219_-|antiholin-like-protein-LrgB
MIEHLGINTPYFGILVSLIPFVIAQYFYKKTNGFFLLAPLFVAMVAGIAFLKLTGISYAQYKVGGDIIYFFLEPATISFAIPLYKKRDVLKKYWLQIFGGITLGTLAALILIYLVSTLFQLGNTVSASMLPQAATTAIALPVSTGIGGVKELTSLAVILNAVVISALGTKIVKWFKISNPIARGLALGTSGHTLGVAAAKDLGETEESMGSIAVVIVGVIIVAIVPPLASILF
>NC_017353.1|WP_002478676.1|607604_608246_+|DUF443-family-protein
MLCESKIINKNPKYRIIKYKDDYLMVDIVSHWFTFLFPMINWFIPKRYAKLSEEEYNNLNIVKPVKNSGASIGVGLAILISVLLRKYVFIFDVQVQQSIAVISCIIGFLCVFIFFLYINKKVTLDIYKINKTHSKIILIPTLKNIGFTLFSYIFLGGFVWMILYGLTVENLYNIFIFIIWIGSIALFFFFNMFAIMDKKVHIILKNKEMNCHG
>NC_017353.1|WP_002460342.1|607159_607471_+|DUF4176-domain-containing-protein
MITIGSIVYLKGGSQKMMILNRGPIIEQDDKKVMFDYSACKYPLGLVENQIYYFNTENVDRVIFEGYSDDDEIRFQELYQEMLNELSDDITRGEVEEKQFGLE
>NC_017353.1|WP_037553687.1|606527_607163_+|DUF443-family-protein
MLCESKIIRMNPKYRIIKYNNDYFMVDTICHWITFLFPMINWFVSKRYAKLSEEEYNNLDIVKPVKNSGASIGAGLAILISALLRNYVNIFNIQIQESVAVLSCVIGFLGVFIFFLHINKKVTLDIYKRNKTHSKTILIPTLKSIGFTLTSYVLCGGCALIIMEMLTIDHLYNVFIFILWVIWIAFFFFINMFAIMDKKVHVILKNKEVKI
>NC_017353.1|WP_002478674.1|605830_606457_+|DUF443-family-protein
MLCESKIINMNPKYRIIKYNDDYLMVDTISHWITFLFPMINWFVPKRYAKLSEEEYNNLDIVKPVKNSGASIGVGIIIILNVLFRKYIDVFNVQVQESVAILSCVIGFLGIFIFFLYINKKVTLDIYKRNKTKSKIILIPTLKNFGFTLFSYLLFGGISWVTMEMLTIDHLYNIFMFIVWIGIIAAFFFVNMFAIIDKKVHIILKNKV
>NC_017353.1|WP_002478673.1|604370_605828_+|transposase
MSIDMYLNKSKNQASNMRKLSQAMNQSYDSLNNAVLQFVTKEDLQGKAYRSAKQFFSAVVIPLSYSMKTLSDMTEEACTTFVERYTQEVDNQSLKESELEEDINELKQRIALLEEINGGLKKYLSEKRDTISRNNRMIASLEQQKHELEEKLRKLQEFNQKSPEIFKDVEAFQDVVKQGLNQLQTSWNPVTKEFNIPSGKDLEWAKVSNEKYLKVAMKKIEEKAKTGKLNKQDGKIIQEYAEKHQDEDLPQSLINYFIQNKDNIKQSLEIDISSKLIEQIGVQSKNIGVFINTAGGYKGPKGPNSFVQVKRTWGDAIIKDSKEFAKNGKILGGVITGLGFFISVRSDLNEGKTCGEALSHNALTMSAGWVTSTIISGTIIALAANPVGWAALAGIAVGTLAAYGADWAYQNNKLGIKDKVDWLGHKMDPVLGQLGQTKDQTIKILDNTATNVSNGVKNTAETVKNTVGEAVNNIGDNMNPMKWKW
>NC_017353.1|WP_002478672.1|604015_604381_+|DUF3958-family-protein
MDKVTTLNNQIYKTNLEVETLTEQQRGLIHLINDYEDATRNTEKLYDRLIYRYGSSNSAFSLEQHRDEFQQEKQAILEELIDNQDNVKHQIRKLNDCIEVLEAQRNIELHKANEKGHDYEH
>NC_017353.1|WP_002478671.1|603727_604000_+|TIGR04197-family-type-VII-secretion-effector
MSEIKSDMSKTYHAYYIINNATRSCSSISEPGKDESTTVSGNKNAHTAIEQLLTINTSITAALEKANTTLKEVGDSFEAMDLTLGNQISK
>NC_017353.1|WP_002460346.1|602737_603418_+|ABC-transporter-permease
MDGNLLQQLAHYYSTNFGYLMGLFFKHLLMSVYGVLFASIVGIPIGIFIARFKKLAWPVITIANVIQTVPAIAMLAILMLALGLGPTTVVVTVFLYGLLPIIKNTYTGIVEVDANIKDAGKGMGMTSNQVLRMIELPLSLSVIIGGIRIALVVAVGIVAIGSFIGAPTLGDIIIRGTNSTDGTAFILAGAIPIALIAILIDIGLRMLERKLDPTQKKKGPQPQTIN
>NC_017353.1|WP_002460335.1|610190_610952_-|DNA-binding-response-regulator
MNILIVDDEPLARNELHYLLDNIPTVKHVEEAENISETLEHLLYASFDAVFLDINLMDESGIDLAEKIKKMQHAPYIIFATAHDTFAVKAFELNATDYILKPFEQQRIEQTIEKIARTKQYVNSAADQNKLEPQNHQNINTHTKQTVLPIEVDERIHVLNVEDIVAVTVNNGITTIHSVNQDYQTSEKLNYYEKKLPTTQFLKIHRSTIINKVHIKTVEHWFNYTYQLTMTSDIKLQVSRSYMKTFKQEIGID
>NC_017353.1|WP_002460334.1|610952_612707_-|sensor-histidine-kinase
MFNLFILLLERVGLIIIIAYLLMNTSHFKTMMGEREKWRSQWQLLIIFGLFAITSNFTGIEIKDGQIISSNIYYHLNSEASMANTRVLTIGASGLIGGPYVALFVGIISGLSRMYIGGADAYTYLISSIIIGLTSGFIGHLAIKNHRYPTVLQGAVIGIINEAIQMLCILIFSEDTTAAIELVQLISLPMILINSIGTAIFLSIILSTLKQEEQARAVQTHDVLQIANETLPYFRAGLNEASAKRVAEVILPLMNVSAVAITNKKDILTHVGAGSDHHIAKKEIITNLSKEVIRSGQLKEAESKEGIGCNHDNCPLEAAIVIPLYTNHNVVGTLKFYFKDKHDVTNSTKQLARGLAEIFSSQLELGKAETQSKLLRDAEIKSLQAQVNPHFFFNAINTISALVRIDSEKARKLLLQLSQFFRSNLQGARNNTITLEKELQQVEAYLSLEQARFPNRFHIDYHIDKQYHHILIPPFIIQILVENAIKHAFKNRKANNHITVTASQHDDAIQLTVTDNGQGIPKERIPLLGQISVNSETGTGSGLENLNRRLIGLYGPTSQLSITSTNKGTRVSCMIPYHEQKEDI
>NC_017353.1|WP_002478679.1|613014_614409_+|MFS-transporter
MNTSQEFRGDNRLLAGIIIGVLTFWLFAQSVVSVIPALQSSFNANIGTINIAVSLTSLFAGLFVVGAGDIADKFGRVKMTYLGLALNIVGSLLIIIAPFPWLLITGRALQGLAGACIMPATLAIVNTYFLGKERQRALSYWSIGSWGGSGICSLFGGWVASTIGWHWIFIISIALSFVAFFLIKHTPETKAETTGSEVKKFDVIGLILLVITLLSVNVVVTQASDKGLFSPMILTLFVVFFIAGFAFLIYENKADNPLVDFHLFRNKGYSGATVSNFMLNGVAGGTIVVINTFYQQKLGFTSGQAGMISITYLISVLIMIRVGEKILQAQGAKRPLLFGSAFTFIGLLLLSLTFLPDIWYIISSVVGYLLFGTGLGMYATPSTDTAVAEAPDEKVGVASGVYKMASSLGNAFGVAMSSTIYGLFASAMNLQWGGAAGVLFNAGIAVLAFFMILLLVPKRTNMTP
>NC_017353.1|WP_002478680.1|614591_615524_+|2-dehydropantoate-2-reductase
MKIAIAGSGALGSGFGAMMYKQNYDVTFIDGWEPQAQAVKQDGLHIDINGEANHLNIPMYHDTEIPKGDQYDVIFLFTKSMQLSDMLEQIKPHIHEHTIMVCTMNGLKHEDVIVNYVDEARIVRGVTVWTAGLESPGHTHLMGAGPVEIGALIPDGQANVDVVFDILKHSGLNPLKSENLQQSIWKKICVNGTANALCTVLECRLSTLNASEYALNLVYKLTQEILAVATIDGVHLNVDDIYDYLVDLNHKVGPHFPSMYQDLINNQRLTEIDYINGAVARLGQEHGIDAPVNQFVTNLIHAKESQRQAK
>NC_017353.1|WP_002478681.1|615705_615972_+|GNAT-family-N-acetyltransferase
MGYLERETFITIAVIAMRNTYFYEIKNIAVDINYQCQGLDRRLMEQIFTDYRGTTMYGGTSDSPVTQSFYRSLGFKYVETNKVFYYQL
>NC_017353.1|WP_002478682.1|616175_617027_+|NAD(P)-dependent-oxidoreductase
MVKIFVTGATGLIGTKLTQRLLEEGYDVAGFTTSEQGKQRLEAANVKAYIGDILKADTIEAAIADFQPEIIINQITDLKKVDMTANTKVRIDGSKNLIDAALKHHVKKVIAQSIAFTYEPGEGLATEETPLDDHSTGDRKITVEGVEGLEEQTARMDNYVVLRFGWLYGPGTWYGKDGMIYNQFIDGEVTLSDGVTSFVHLDDAVETSIQAINFANGIYNVADDEPVKGSDFAQWYKQQLKVNPKVNITPAEPFERGVSNEKFKSQGGTLQYKSWKDGMNPIQ
>NC_017353.1|WP_014533224.1|617090_617912_-|membrane-protein-insertase-YidC
MNKHTRLLFFSCILLLAGCNYSKKQHQTGFFFYVFVKPIDWLLHSIGQLFHSYGIAIILIVIIIRSILLPLMLNQMKQMHTLREKRAIVQDEISDIQTQMRQASTPEIRKEANQLLLAKYKEYGISPFKSILGSLPIFIQIPIILGLLACIKHPTSDALAQHPHFLWFNLMHPDIWLALLAGLFYFIQPLVNAIHYPKGQRKTYYTMMVLSPLFIIYASLHSAAAISLYWVVSASFLIVQTHFGHRRYKKQAQAAAIQLENYIAQRDQTSSQH
>NC_017353.1|WP_012990737.1|618023_619535_-|serine-hydrolase-FLP
MKKKIFAFLGGTIFVVTILTIAMIINHHINQKKTETMLSKSSQHYIDKIITSEMDSGHIPGLSVLIMKDNKVYLNKGYGYANTSTKVKATPKTRYEIASNTKAFTGYAILQLENEGKLHLSDKVSKYVPGFYMKYKDKRIDDITINQLIAQTSGIPGDITDNDTITSKNDSLSGIVDSIKGRELNNKPGDQFEYSNMNYDILGLIVQKVSGQSYSSYLENQIFSPLNMHQTYVKGDTEKKGSTAQGYEIKHGKAVKDNPKYNVGDGPAAYMVSSTKDLESWMSRQLNPTQATQSLVQSSHKPKVKTADDNKAPSYATGWFVDDSEANTIVYHPGTLENFSSYILLNKKKNYGIVVLANAYSDKTPDIAEDLNSQILNNKNYTTIENAINQSSLVSYVIITLSLFITIAIAFYMLRRIINIYHGTFVIHVQWKLLGYFLIIMAVFISLMTAIYLLPDLVMGNTNWDFIMVWLPLHAKLALWSVMLTILCATITLVTMLFSKKKR
>NC_017353.1|WP_002460323.1|619816_621643_+|APC-family-permease
MFNQFKRLIIGKPKRNRELKNEKISKFKALAILSSDALSSVAYGPEQILLTLSIVGAAAAWYTLPIAVAVLILLAALTLSYRQIIYAYPKGGGAYMVSKSNLGEKWGLLAGGSLLVDYILTVAVSISSGADALVAAIPTLYSHKVLIACLLVLFILLLNLRGLTESATVLSYPVYLFIVGLIVMIIIGTFKVATGQAEPHMQSAVGTAVPGVSLFLLLKAFSSGASSLTGVEAISNAVTNFKEPGPNNAVKTLIAMGSILGFLLVGIVGLSYWYGILPQEETTVLSQLAKHVLGQNVAYYFVQATTVMILVLAANTGFTAFPMLAASMAKDKYMPVMFTARGDRLGYSNSIIVLGVLAIILIILFDGKTENLIPLYATGVFIPFTLAQFGMVIKWIKGREKGWAVKLIANAVGGTITFVVFMIFLITKFNQVWPILIFLPIVVIGFLKIRMHYRDIAEQLRSNAMIQDMPIVDKNLALVPISSITSAVDKSIYYAQMIADDVIAVHVSFGDKDETCLQNKWKAHFPDIRLVILRSEYRSVIRPISRFIDKINKKANDKNYVITVVVPQFVTKKPWHNFLHNQTSIRLKMHLFYQKNVILATIPYKLKK
>NC_017353.1|WP_002478684.1|622031_622976_+|hypothetical-protein
MRKGIVMILLALGLTLAGCSHHDNDNKESSTKSDKSSKTDTETVKIKDDDKMTDKEKEYKELEKKASKKEKVDIMGKLDPLVTEKSLTNKTGMQGWKDYKELMKKVEIADYNYVKESKGASMKEVDDFFKDKKGVKRKEIKNPGGLKQIDYWYVDPSGKKIGKSNIPEFYAEILTKYKDGKLVYASIEPGFYTADFAKALDGDKMKDIKTLNQLVAPKPVSYGIGQMKYSGIPLVNVSVIAKAPAKKKEDQVPVLAFYTFSPFNYNSDKEPQVAYLSGIEFMSGSRDFGNSNYLSMMKFIKEQKEVLDQGVHDS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017353_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017353_5

698066-698214

Orphan

Consensus_repeat	Method
TTTGTTGGGGCCCCACCCCAACTTGCTTTGTCCGTTGCCTTTCTTTTG	PILER-CR

2 spacers

The CRISPR arrays of NC_017353_5

>merge|NC_017353|5|698066-698214|PILER-CR
CACCCCAACTTGCTTTGTTTGGTGAATTTCTTATCGAAATTCTCTTTGTTGGGGCCCCACCCCAACTTGCTTTGTCCGTTGCCTTTCTTTTGGAAAGCCATTTTGTTGGGGCCCCACCCCAACTTGCTTTGTCCGTTGCCTTTCTTTTG

>NC_017353|5|2|698066-698214|PILER-CR
CACCCCAACTTGCTTTGTTTGGTGAATTTCTTATCGAAATTCTCTTTGTTGGGGCCC	CACCCCAACTTGCTTTG
TCCGTTGCCTTTCTTTTGGAAAGCCATTTTGTTGGGGCCCCACCCCAACTTGCTTTG	TCCGTTGCC
TTTCTTTTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017353.1\|WP_002478730.1\|690572_691160_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_017353.1\|WP_002478737.1\|701619_701832_-\|hypothetical-protein	unknown	unknown	unknown
NC_017353.1\|WP_002478742.1\|706792_707404_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376540
NC_017353.1\|WP_002478729.1\|689456_690353_+\|urea-transporter	unknown	unknown	gnl\|CDD\|163267
NC_017353.1\|WP_002478735.1\|699410_701024_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NC_017353.1\|WP_002478741.1\|705835_706366_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|225695
NC_017353.1\|WP_002478733.1\|697283_697928_+\|DUF443-family-protein	unknown	unknown	gnl\|CDD\|273508
NC_017353.1\|WP_002478732.1\|696147_697053_+\|EamA-family-transporter-RarD	unknown	unknown	gnl\|CDD\|225510
NC_017353.1\|WP_002478734.1\|698450_699083_+\|stage-II-sporulation-protein-M	unknown	unknown	gnl\|CDD\|376676
NC_017353.1\|WP_002478740.1\|704940_705792_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NC_017353.1\|WP_002478731.1\|691363_693139_+\|oleate-hydratase	unknown	unknown	gnl\|CDD\|237575
NC_017353.1\|WP_002460241.1\|686345_686798_-\|urease-accessory-protein-UreE	unknown	unknown	gnl\|CDD\|237322
NC_017353.1\|WP_002478727.1\|688525_688933_-\|urease-subunit-beta	unknown	unknown	gnl\|CDD\|237302
NC_017353.1\|WP_002478739.1\|703652_704798_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NC_017353.1\|WP_002460231.1\|693856_695593_+\|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl\|CDD\|236451
NC_017353.1\|WP_002478738.1\|702809_703445_+\|DUF443-family-protein	unknown	unknown	gnl\|CDD\|335700
NC_017353.1\|WP_002478728.1\|688945_689248_-\|urease-subunit-gamma	unknown	unknown	gnl\|CDD\|183913
NC_017353.1\|WP_002478743.1\|708228_709014_-\|hypothetical-protein	unknown	unknown	unknown
NC_017353.1\|WP_002478736.1\|701224_701602_-\|hypothetical-protein	unknown	unknown	unknown
NC_017353.1\|WP_002478726.1\|686810_688526_-\|urease-subunit-alpha	unknown	unknown	gnl\|CDD\|237305

Protein	Function_ID	Function_description	E-value
NC_017353.1\|WP_002478730.1\|690572_691160_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.85673e-12
NC_017353.1\|WP_002478742.1\|706792_707404_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|376540	pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within Neisseria gonorrhoeae NGO_0477, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteristic of the whole family.	1.24822e-08
NC_017353.1\|WP_002478729.1\|689456_690353_+\|urea-transporter	gnl\|CDD\|163267	TIGR03441, urea_trans_yut, urea transporter, Yersinia type. Members of this protein family are bacterial urea transporters, found not only is species that contain urease, but adjacent to the urease operon. It was characterized in Yersinia pseudotuberculosis. Members are homologous to eukaryotic members of solute carrier family 14, a family that includes urea transporters, and to bacterial proteins in species with no detectable urea degradation system. [Transport and binding proteins, Other].	1.81281e-82
NC_017353.1\|WP_002478735.1\|699410_701024_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NC_017353.1\|WP_002478741.1\|705835_706366_+\|N-acetyltransferase	gnl\|CDD\|225695	COG3153, COG3153, Predicted acetyltransferase [General function prediction only].	1.27717e-52
NC_017353.1\|WP_002478733.1\|697283_697928_+\|DUF443-family-protein	gnl\|CDD\|273508	TIGR01218, conserved_hypothetical_protein, tandem five-transmembrane protein. Members of this family of proteins, with average length of 210, have no invariant residues but five predicted transmembrane segments. Strangely, most members occur in groups of consecutive paralogous genes. A striking example is a set of eleven encoded consecutively, head-to-tail, in Staphylococcus aureus strain COL.	1.10635e-29
NC_017353.1\|WP_002478732.1\|696147_697053_+\|EamA-family-transporter-RarD	gnl\|CDD\|225510	COG2962, RarD, Predicted permeases [General function prediction only].	2.55223e-96
NC_017353.1\|WP_002478734.1\|698450_699083_+\|stage-II-sporulation-protein-M	gnl\|CDD\|376676	pfam01944, SpoIIM, Stage II sporulation protein M. SpoIIM is on e of four stage II sporulation proteins that is necessary for the forespore inside the mother-cell to be properly internalized through the breakdown of peptidoglycans trapped between the membranes of the septum separating the forespore and the mother-cell. The four proteins working in sequence are SpoIIB, pfam05036, SpoIIM, SpoIIP, pfam07454, and finally SpoIID, pfam08486. D, M and P are in a complex with each other and the complex assembles in a hierarchical manner such that M, which serves as a membrane anchor, recruits P to the septum and P, in turn, recruits D to the septum.	1.10167e-06
NC_017353.1\|WP_002478740.1\|704940_705792_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	2.64264e-27
NC_017353.1\|WP_002478731.1\|691363_693139_+\|oleate-hydratase	gnl\|CDD\|237575	PRK13977, PRK13977, myosin-cross-reactive antigen; Provisional.	0
NC_017353.1\|WP_002460241.1\|686345_686798_-\|urease-accessory-protein-UreE	gnl\|CDD\|237322	PRK13261, ureE, urease accessory protein UreE; Provisional.	4.53278e-58
NC_017353.1\|WP_002478727.1\|688525_688933_-\|urease-subunit-beta	gnl\|CDD\|237302	PRK13201, ureB, urease subunit beta; Reviewed.	1.96761e-87
NC_017353.1\|WP_002478739.1\|703652_704798_-\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	6.17378e-58
NC_017353.1\|WP_002460231.1\|693856_695593_+\|phosphomethylpyrimidine-synthase-ThiC	gnl\|CDD\|236451	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional.	0
NC_017353.1\|WP_002478738.1\|702809_703445_+\|DUF443-family-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	5.1115e-48
NC_017353.1\|WP_002478728.1\|688945_689248_-\|urease-subunit-gamma	gnl\|CDD\|183913	PRK13241, ureA, urease subunit gamma; Provisional.	3.1122e-64
NC_017353.1\|WP_002478726.1\|686810_688526_-\|urease-subunit-alpha	gnl\|CDD\|237305	PRK13207, ureC, urease subunit alpha; Reviewed.	0

>NC_017353.1|WP_002478733.1|697283_697928_+|DUF443-family-protein
MKHVTIDSIKNNSKYKIIHDGEKHYVIDLNRNKLTYIFPLLNYLLPHRLMEISDDAYFSLTTVQQSVESKVKNMMITLIGIVILFIYYRANVVDNFFLKHYPPLIIIALMVLIFIIKWLIDKRKRKRLNIEQIETEKRAYIFPEIFTMVISIILYVIAVVSFVFLSFKIFGSMGEPHLNSNVLIIMLAIILSFDQLLYSNSETSGKMSHIKVKA
>NC_017353.1|WP_002478732.1|696147_697053_+|EamA-family-transporter-RarD
MNSNIEFKKGVLFALGAHLLWGILPIYWRLIGNISAFEILAYRIILSMIFMIIMIYILKQSTAFKRDLTHLFATPIQLIAIIVAGYVITLNWGTFIWAVSNGHVLQTSLGYYINPLVSILLAFIFLKERFNKFESLAIVFAAIGVLYMTIRVGEFPMISLMLAFSFGIYGLLKKLVRVDAMTGIAIECIVTAPAGLIYIIYLWQIHHTSVGINMASFWLLFSGAVTAVPLILFSAGARRIPLSLTGFIQYVSPTIIFLLGIFVFKEPFDIHQFITFIFIWIGIALYSISQYVKMKRNVRPE
>NC_017353.1|WP_002460231.1|693856_695593_+|phosphomethylpyrimidine-synthase-ThiC
MKQEMIRFKKNFPASKRIFKKGSDDDIAVPFRQIELSDTQLENDAFHNDPITVYDTAGPYHDDNYDVNIDSGIPQLRKSWIDARQDVESYKGRKIQSIDNGFKKEGHKNYVAHPFQYQPKRAKQGGNVTQMHYAKQGIITKEMKFVAVREQVEPEFVRDEIARGRAIIPNNVNHPESEPMIIGKNFAVKVNANIGNSVVSSSIEAEIEKLVWAIHWGTDTMMDLSTGKNIHSTREYLIRNSPVPVGTVPIYQALEKVNGVAEDLTWEVYRDTLIEQAEQGVDYFTIHAGLLLHYIPLTVDRLTGIVSRGGSIIAQWCLAHHEESFLYTHFEDICKILNQYDVAISLGDGLRPGSIYDANDESQISELKTLGELTEIAWKHDVQVMIEGPGHIPMHKIKENQDLADFYCKEAPFYTLGPLVTDIAPAYDHITSAIGAAQIASHGTAMLCYVTPKEHLGLPNKDDVRDGVVTYKIAAHAADLAKGLPGATVRDDAISKARFEFRWIDQFNLSLDPDRAREFHDETLPSESAKIAHFCSMCGPKFCSMKLSHDIRDSYKEQLAGMKEKAKEFQAAGNKIYH
>NC_017353.1|WP_002478731.1|691363_693139_+|oleate-hydratase
MYYSNGNYEAFARPKKPENVEQKSAYLIGSGLASLAAACFLVRDGQMDGAKIHVLEELAKPGGSLDGDELPMKGYVVRGGREMENHFECLWDLFRSIPSLEVEGASVLDEFYWLNKEDPNYSRCRVIEKRGHQLPTDGDFTLTKQAIKEMIDLCLMTEEDLNDVMISEVFSKDFMNSNFWIYWKTMFAFEPWHSAMEMRRYLMRFVHHIGGLADFSALKFTKYNQYESLVLPMIAYLESHGVQFEYDVQVLDIKVDVTTTEKVAREMKLKRQGKEETMLLTPNDLVFVTNGSITESSTYGDNETPAPPTKVTGGSWNLWRNLAKQSPEFGHPEKFYQDLPEKSWFVSATATTNNKRIIDTIESICKRDPLAGKTVTGGIITVNDSAWQMSFTVNRQQQFKAQPKDEVSVWIYALYSNVKGDYINKPIVECSGNEICQEWLYHMGVPTNQIKDLAQNQCNSIPVYMPYICSYFMPRAIGDRPLVVPHQSRNLAFIGNFAETERDTVFTTEYSVRTAMEAVYQLLNIDRGVPEVVATEFDLRVLMDAMYELNDGKGLVELVEQKKLKQVALNAFLKKIKGTYIEQLLIQHKLL
>NC_017353.1|WP_002478730.1|690572_691160_-|TetR/AcrR-family-transcriptional-regulator
MNKQDLRVQKTHQALMTAFHQLLKTKTFEQITIQDLCHKANIRRSTFYRHFNDKYHLLNHVVGILIDHFRELYLPEINPDNPRQFFEKLMTDILTFIHHHKDTVRSVITLNFYGEVYNIFYDQIYAAVKKQIDFDKQNGQFYVDVTIYSEFLTGGILSVITNWIQHGQQQPIDKVVNEIVTIICGAREIHLKKLK
>NC_017353.1|WP_002478729.1|689456_690353_+|urea-transporter
MEKIDVFLKNIAQVVLINSKWTGLFILIGLFVADWELGLAAVLGSALSVLLAPYFNYSAEEIHNGLAGYNSVLTAIGLALFLQSTTIAWIVLVISVILTLPLGAATREFLKSYGVPMLTFPFVLMTWLILAMTTQFSTLSVTVDILPLHVKHPVISHHHISWLSGITTNFSEIFLVTSIGGSVLILIGIFLGSIKGGVYALISSIFAVACIALLGGDYPTIANGLYGYNAVLTGIALGATFMTKLNKYIAVITGLLLTIVMHGALATLLTPVGLPILTAPFIFATWLVLFAGKMSNEN
>NC_017353.1|WP_002478728.1|688945_689248_-|urease-subunit-gamma
MHFTQREQDKLMIVVAAEVARRRKARGLKLNHPEALALISDELLEGARDGKTVADLMSYGKTILNEEDVMDGVASMITELEIEATFPDGTKLITVHHPIV
>NC_017353.1|WP_002478727.1|688525_688933_-|urease-subunit-beta
MIPGEIKVKNTDIEINQGHPETVLTVKNTGDRPIQVGSHFHFYEANKALKFEREKAYGKHLDIPAGAAVRFEPGDEKKVQLVEYAGHRNIYGFRGMVNGKIDETRVYRPTGEHDSYAGVFNDQGEENLNKKGGQD
>NC_017353.1|WP_002478726.1|686810_688526_-|urease-subunit-alpha
MSFKMTQSQYTSLYGPTVGDSVRLGDTNLFAQVEKDYANYGDEATFGGGKSIRDGMAQNPNVTRDDRKVADLVLTNALIIDYDKVVKADIGVKNGYIMGIGKAGNPDIMDNVDIIIGATTDIIAAEGKIVTAGGIDTHVHFINPEQAEVALESGITTHIGGGTGASEGTKATTVTPGPWHIHRMLEVAEALPINVGFTGKGQAVNHTALIEQIHAGAIGLKVHEDWGATPSALRHALDVADEFDVQIALHADTLNEAGFMEDTMAAVKDRVLHMYHTEGAGGGHAPDLIKSASYPNILPSSTNPTLPYTQNTVDEHLDMVMITHHLNASIPEDIAFADSRIRKETIAAEDVLQDMGVFSMISSDSQAMGRVGEVIIRTWQVAHRMKEQRGGLEGDTEYNDNHRIKRYIAKYTINPAITHGISDYVGSIESGKLADLVMWDPIFFGVKPELVVKGGLINSAVNGDANGSIPTSEPQKYRKMYGQYGTNIQHTAITFVSTTAYENGIYNLLNLKRMVRPVHGIRNLSKKDMKHNHATPKLDVDPQTYEVFVDGEKITSEAATELPLTQRYFLF
>NC_017353.1|WP_002460241.1|686345_686798_-|urease-accessory-protein-UreE
MIIEEIQGNIANLTAEEKSKHIEKVYLENSDLVKRIQRVTTDHGTELGIRLRQPIDLQYGDILYQDETNMIVVDVNSEDLLVIQPRTLQEMGDIAHQLGNRHLPAQFTETEMLVQYDYLVEDLLKTLGIPYSHEDRKVNKAFRHIGHSHD
>NC_017353.1|WP_002478734.1|698450_699083_+|stage-II-sporulation-protein-M
MINIGGDTLIKSIDKNVYKHALKVFALATIILMITTVITYFCHPAINDVKHLGNSSTNISSNPQGLSKVWHFIVNNGCFVPVQMFILALIPIPFLYMLNIVISVIIPGIMFGIFLNFDLHKAFTAIIAYIPHYTLEIMAYCILASGLYMLNKAIVRKVTNLFRKKKKDNYPFKKSLFKVIKIYFIFTLPLIILAAFTETYVADWIYQLMN
>NC_017353.1|WP_002478735.1|699410_701024_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MNILNASNISKKYTEDILFDHIKITLNSGDTLGLVGRNGEGKTTLLKLLSGMERPSTGVISWKKDIKIGYLNQIPDYEKSESVYQCIKSVFKELDTISKQLETIETKMIEERENINSLVARYGELQTYYEENGGYEIDAKIRKVTHGLNIAHLLKAKWGDLSGGERTKVGIAQMLIKPTDLLLLDEPTNHLDVKSIEWLASYIKNNDSATVIVSHDRYFLDETVNQIIEIDQKKLHFYNGNYSYFVEERDKRLLIEFEAYKTQQKKIKKMKESIKQLRTWASQAKPPNAAMFRRAKSMEKALNRIQRLEKPLLDSKKMHITLEEGMNVSNRVIEMENVTKAYDDVLFRNVNMLIRRGEHVAIIGDNGTGKTTLLKIILGLTSIDKGSIKTASNLKIGYLSQHEFERDGNDTLLHTFRKKVNVSEDQARHILAHFMFYGKDVFKKVNELSGGEKIRLRWAQLVNTDYNLLVLDEPTNHLDIDAKEIIEDALLDFNGTIITVSHDRYFLNKLFNTTYLLKNKTLEKFEGNYDYIKEKML
>NC_017353.1|WP_002478736.1|701224_701602_-|hypothetical-protein
MKKRIFLCLIFLLPIDFITIALDYHFQVGLLYVYIPALILPVILTFCFKWEKDFRLILSMKVCRFIISWGLAKIFIDFMKSAEYYEMFDGAGAIISLVIGEEIIFIIAITVFLLSKEIKKLFITQ
>NC_017353.1|WP_002478737.1|701619_701832_-|hypothetical-protein
MSSNFVIVIITILMIVCIDAIFYYVSKIKHAPKKILITMVAFFVSIFLVFLFIIAILEIGAMVDTGQLFV
>NC_017353.1|WP_002478738.1|702809_703445_+|DUF443-family-protein
MENVYTIYKNPRYKIIQKDNRYLMIDLEQNWYSYLCPMLNWFIPIKYTELSYKEFNNLNIFNNQNQSNQGLIAAGIGVTISVLLRSFIGLMNINISQIWMFVLFLIGFVGVIALRLSIRKKLNHPAFNKNSTQKVMLIPSFKNMVLVVFCYLISIYLIVGLFYMMVIENIQNIWIYICWLGIFFVFSFMNMASISDRKVHAKIKNIERQVK
>NC_017353.1|WP_002478739.1|703652_704798_-|MFS-transporter
MKKVWVLTIGMFALGMDAYIVAGLIPAIGDNFNKNSAEVGQGVTVFTLFFAISAPIFSTLLAKNEVKNILILAISVFSLANLITALAPNYAIYIISRAIAGLGAGIFSPIAVSSSSHLVSKKHKGKAIAFTVGGMSVGTVVGVPLGLEVSKYTNWRFSILIIVLIGLIGLMSILKYLPRFKVQAPPNLKSRFKLFLDKHVLSVVFVTLCAAIASLGLYTYLADIIKESGNTEYLTCYLTAWGVGGLIGSFGIGFLIDKFKNPAVLMLIILFALALSFALLNVTIQVPFLNFIPFILWGAMGWATQAPQQHILLQNHANHGGAAVALNSSINYLGSALGSALGGIILLKFINTNMLIYSAIIITVIGIMLQIMNITIDRKNN
>NC_017353.1|WP_002478740.1|704940_705792_+|LysR-family-transcriptional-regulator
MNFEYIQDFIRVAEYNSINKASQELNISTPALSKRIKSVEAYFNCHLFYRTSKGIFLNEEGKLVFNTFREMQHSIADLKKQLNISFDSKWKIGVIPSFSLTNKYKNRGFDEIANLIIEDSTSILIEELSKGNIDLLIGDVSKLNNRDIYRKRLYSENFMVIYNDDNKFTESSKIEINELLSEKIYIQNPPCDTYDFIKNRSMEDKLNLNYNKHFESVIANIKAGNGITLMPVSLTSRISNMNLFQKVLSGYKRDIGIASYDQRKIIKIYDFLLKNLEEERNQK
>NC_017353.1|WP_002478741.1|705835_706366_+|N-acetyltransferase
MDFTIRTEEKEDYKFTEEVVKNAFANESYSDQSEHRLVANLRNSDAFVPDLSLVAVDKNKMIGHILLTKIVIVNDEKNTESLALAPVSVLPDYQNKGVGRSLIQKSLEIAKKLNFGSVIVMGHAEYYPKFGFKQASNWGIQAPFDVPDELLMAIELKKNALDEASGVIQYSSAFFE
>NC_017353.1|WP_002478742.1|706792_707404_-|helix-turn-helix-transcriptional-regulator
MDKSRVAKIIKSKSMTQENLAEKACVTVRTIQRIEAGEEVSSKTLKSISNALDVTINELFESIDSPDKEAEIMEISKEQQKQFKYRQNEIFTIRLIIFGVIFLLLAFFAIFISELNGLKQEIFGIIWLFTLFLSLAIAHYFLNVFISKKLDEKYPMTLGMNNKRSHRRNESASNGWDFLSRNWWMIFPIGGFLSWLIPQLLGK
>NC_017353.1|WP_002478743.1|708228_709014_-|hypothetical-protein
MRVLLLFIGTILVTILIIGSMMGFFNNSIPPWMLIIFWAASIVILLGTVMIRRYYKQKYKRELTLYEKSPNLQENEFFYQAPLYLFDDIYIKIHGMTDTVWTPYFNNNLQKWLSILDIFPTYGVKLTSSDHDIILKRVKLWSLRPHYRVCIDGSEVGILQMIKLVKGGIKQQTPYVFLDINYTYKFNNPYFSTKTVIIGKENNKILTAQRSFFDLGKNLVTRRRGENHNIEIESNDTPIPYPPELWITLYIQVMINKQKEQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017353_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017353_6

750787-750873

Orphan

Consensus_repeat	Method
GCAAGTTGGGGTGGGGCCCCAACACAAAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017353_6

>merge|NC_017353|6|750787-750873|CRISPRCasFinder
GCAAGTTGGGGTGGGGCCCCAACACAAAGAAATGCAACAAGCATTTCCACGAACAACGCAAGTTGGGGTGGGGCCCCAACAAAAAGA

>NC_017353|6|5|750787-750873|CRISPRCasFinder
GCAAGTTGGGGTGGGGCCCCAACACAAAGA	AATGCAACAAGCATTTCCACGAACAAC
GCAAGTTGGGGTGGGGCCCCAACAAAAAGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017353.1\|WP_012990759.1\|751994_752903_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223730
NC_017353.1\|WP_002478778.1\|753916_754864_+\|magnesium/cobalt-transporter-CorA	unknown	unknown	gnl\|CDD\|213365
NC_017353.1\|WP_002478777.1\|753330_753798_-\|thioesterase-family-protein	unknown	unknown	gnl\|CDD\|372545
NC_017353.1\|WP_002478773.1\|748777_750742_+\|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|129794
NC_017353.1\|WP_002478779.1\|756086_756695_-\|DNA-3-methyladenine-glycosylase	unknown	unknown	gnl\|CDD\|187726
NC_017353.1\|WP_002460169.1\|748117_748765_+\|HlyD-family-secretion-protein	unknown	unknown	gnl\|CDD\|224482
NC_017353.1\|WP_037540600.1\|756953_757148_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224393
NC_017353.1\|WP_002478781.1\|758788_759442_-\|MOSC-domain-containing-protein	unknown	unknown	gnl\|CDD\|225167
NC_017353.1\|WP_002478768.1\|741864_742533_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NC_017353.1\|WP_002478774.1\|751078_751786_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223964
NC_017353.1\|WP_002478776.1\|752935_753325_-\|hypothetical-protein	unknown	unknown	unknown
NC_017353.1\|WP_002460174.1\|743752_744214_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_017353.1\|WP_012990757.1\|744311_745685_+\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|226987
NC_017353.1\|WP_002460180.1\|740004_740679_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_017353.1\|WP_002478780.1\|757702_758713_+\|aldose-1-epimerase	unknown	unknown	gnl\|CDD\|185696
NC_017353.1\|WP_002478771.1\|745786_746992_+\|multidrug-effflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340878
NC_017353.1\|WP_002460158.1\|754909_755962_+\|type-2-isopentenyl-diphosphate-Delta-isomerase	unknown	unknown	gnl\|CDD\|235465
NC_017353.1\|WP_002478769.1\|742623_743577_-\|YdcF-family-protein	unknown	unknown	gnl\|CDD\|99750
NC_017353.1\|WP_002478772.1\|747433_747985_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_017353.1\|WP_002478767.1\|740806_741868_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223650

Protein	Function_ID	Function_description	E-value
NC_017353.1\|WP_012990759.1\|751994_752903_+\|alpha/beta-hydrolase	gnl\|CDD\|223730	COG0657, Aes, Esterase/lipase [Lipid metabolism].	1.46957e-45
NC_017353.1\|WP_002478778.1\|753916_754864_+\|magnesium/cobalt-transporter-CorA	gnl\|CDD\|213365	cd12831, TmCorA-like_u2, Uncharacterized bacterial subfamily of the Thermotoga maritima CorA-like family. This subfamily belongs to the Thermotoga maritima CorA (TmCorA)-like family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. Members of the TmCorA-like family are found in all three kingdoms of life. It is a functionally diverse family which includes the CorA Co2+ transporter from the hyperthermophilic Thermotoga maritima, and three Saccharomyces cerevisiae proteins: two located in the plasma membrane: the Mg2+ transporter Alr1p/Swc3p and the putative Mg2+ transporter, Alr2p, and the vacuole membrane protein Mnr2p, a putative Mg2+ transporter. Thermotoga maritima CorA forms funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport by a related protein, Saccharomyces cerevisiae Alr1p. Natural variants in this signature sequence may be associated with the transport of different divalent cations. The functional diversity of the MIT superfamily may also be due to minor structural differences regulating gating, substrate selection, and transport.	2.57866e-137
NC_017353.1\|WP_002478777.1\|753330_753798_-\|thioesterase-family-protein	gnl\|CDD\|372545	pfam13279, 4HBT_2, Thioesterase-like superfamily. This family contains a wide variety of enzymes, principally thioesterases. These enzymes are part of the Hotdog fold superfamily.	4.50419e-30
NC_017353.1\|WP_002478773.1\|748777_750742_+\|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	8.28346e-138
NC_017353.1\|WP_002478779.1\|756086_756695_-\|DNA-3-methyladenine-glycosylase	gnl\|CDD\|187726	cd00540, AAG, Alkyladenine DNA glycosylase catalyzes the first step in base excision repair. Alkyladenine DNA glycosylase (AAG), also known as 3-methyladenine DNA glycosylase, catalyzes the first step in base excision repair (BER) by cleaving damaged DNA bases within double-stranded DNA to produce an abasic site. AAG bends DNA by intercalating between the base pairs, causing the damaged base to flip out of the double helix and into the enzyme active site for cleavage. Although AAG represents one of six DNA glycosylase classes, it lacks the helix-hairpin-helix active site motif associated with other BER glycosylases and is structurally distinct from them.	3.79179e-74
NC_017353.1\|WP_002460169.1\|748117_748765_+\|HlyD-family-secretion-protein	gnl\|CDD\|224482	COG1566, EmrA, Multidrug resistance efflux pump [Defense mechanisms].	5.91566e-37
NC_017353.1\|WP_037540600.1\|756953_757148_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	6.81678e-27
NC_017353.1\|WP_002478781.1\|758788_759442_-\|MOSC-domain-containing-protein	gnl\|CDD\|225167	COG2258, COG2258, Uncharacterized protein conserved in bacteria [Function unknown].	1.21515e-67
NC_017353.1\|WP_002478768.1\|741864_742533_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	8.93373e-88
NC_017353.1\|WP_002478774.1\|751078_751786_-\|hypothetical-protein	gnl\|CDD\|223964	COG1033, COG1033, Predicted exporters of the RND superfamily [General function prediction only].	0.00455323
NC_017353.1\|WP_002460174.1\|743752_744214_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.40067e-15
NC_017353.1\|WP_012990757.1\|744311_745685_+\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|226987	COG4640, COG4640, Predicted membrane protein [Function unknown].	6.36431e-85
NC_017353.1\|WP_002460180.1\|740004_740679_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.74683e-75
NC_017353.1\|WP_002478780.1\|757702_758713_+\|aldose-1-epimerase	gnl\|CDD\|185696	cd09019, galactose_mutarotase_like, galactose mutarotase_like. Galactose mutarotase catalyzes the conversion of beta-D-galactose to alpha-D-galactose. Beta-D-galactose is produced by the degradation of lactose, a disaccharide composed of beta-D-glucose and beta-D-galactose. This epimerization reaction is the first step in the four-step Leloir pathway, which converts galactose into metabolically important glucose. This epimerization step is followed by the phosophorylation of alpha-D-galactose by galactokinase, an enzyme which can only act on the alpha anomer. A glutamate and a histidine residue of the galactose mutarotase have been shown to be critical for catalysis, the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate, and the histidine as the active site acid to protonate the C-5 ring oxygen. Galactose mutarotase is a member of the aldose-1-epimerase superfamily.	2.40518e-86
NC_017353.1\|WP_002478771.1\|745786_746992_+\|multidrug-effflux-MFS-transporter	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.29274e-79
NC_017353.1\|WP_002460158.1\|754909_755962_+\|type-2-isopentenyl-diphosphate-Delta-isomerase	gnl\|CDD\|235465	PRK05437, PRK05437, isopentenyl pyrophosphate isomerase; Provisional.	5.83852e-179
NC_017353.1\|WP_002478769.1\|742623_743577_-\|YdcF-family-protein	gnl\|CDD\|99750	cd06259, YdcF-like, YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been idenitified. The family also includes Escherichia coli sanA and Salmonella typhimurium sfiX, which are involved in vancomycin resistance; sfiX may also be involved in murein synthesis.	1.00927e-46
NC_017353.1\|WP_002478772.1\|747433_747985_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	5.8895e-08
NC_017353.1\|WP_002478767.1\|740806_741868_+\|ABC-transporter-permease	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	3.96093e-11

>NC_017353.1|WP_002478773.1|748777_750742_+|DHA2-family-efflux-MFS-transporter-permease-subunit
MTTTFIIGYIVVALIFIGLINFFVVKSRKKNKNKGQFKEQRNLQDSKSQQSKFKISDLDKEEMSKNGFNQSKSNDIEDDKRKHQFNDTTEHIATTETGDTSDKLQHADETSHGVNQGDDAHDAINPNSVEGRVNEQIKNQNEDFVFGKNVTRAQIIAAMLFGMFIAILNQTLLNVALPRINTEFNISASTGQWLMTGFMLVNGILIPISAFLFNKYSYRKLFIIALTLFTLGSLVCAISTNFPIMMTGRVLQAIGAGILMPLGSNVIVTIFPPERRGVAMGTMGIAMILAPAIGPTLSGYIVQNYHWNVMFYGMFILGLIAIIIGFIWFRLYQRTTNPKADYQGVVYSTIGFGALLYGFSEAGNKGWGSTEIIVMFILGAVFITLFVIRELTMKAPMLNLEVLKSSTYTLTTIINMVVMMSLFGGMILLPIYLQNLRGFSALDSGLLMLPGALVMGALGPVAGKLLDTVGLKPLALFGIAVMTYGTYELTKLNLDTPYMHIMSIYIIRSFGMAFVMMPLMTAAINALPPRLISHGNAFLNTMRQLAGSIGTAILVTVMTTQTTQHFNAFSTELDKTNPVVQDHMRELATQYGGEQGAMKVLSMFVQKISSVDGINDAFWIATALSILAFILSLFLKSKKKADAEHDKMMSKEHI
>NC_017353.1|WP_002460169.1|748117_748765_+|HlyD-family-secretion-protein
MKKLILINVITIVVLAVIGIIGFHFYNNATSYVTTDNAKVDGKQIKIASPTSGQIKSFDAKEGDKLSKGDKVATVVGKSESGDTQSMDIKMPQNGTIVKTDGAEGSMAQAGNPIAYAYNLDELYITANVDEKDVSSIEKGNDVDVTIDAQGTTVSGKVEHVGQATANSFSLMPSSNSDGNYTKVSQVVPVKISLDSTPSKDVVPGMNAEVKIHKN
>NC_017353.1|WP_002478772.1|747433_747985_-|TetR/AcrR-family-transcriptional-regulator
MKNRAKYRIIFNFVHLLEQYPFEAITTKLICAHSNVNRSTFYANFKDKYDLYDIIQNYHKKKYINLLDTLYNDFEDVKSNNMKIHKFFVIVLKYIQRKKAFFHAVFITHPNREIAIEYFQLTKVKYEKILTDYNTTIENKSAFVTYTLGGQTAILLSWLKDGCQESPHKIADILLANTIKLQR
>NC_017353.1|WP_002478771.1|745786_746992_+|multidrug-effflux-MFS-transporter
MSSQQRDKQSLIFIIILGALTAIGPLSIDMFLPGLPEIKHDFNTSTAISQLTLSLFMIGLALGNLFVGPISDAIGRKMPLVVSMFIFTLASFSIIFVSNIWVMIVLRFVQGLTGGASAVISRAIASDLYSGKALTKFLALLMLVNGIAPIIAPTLGGIILSVSIWRTVFIVLTVFGILMLLGSALKVTESLHIEQRETSGIKVIFKNFGKLLATPKYVLPMLIQGVTFIMLFSYISASPFLIQKIYGQSPFAFSLIFASIGVTLIISSQLTGKLVDYVDRQQLLRILTVIQIVGVIIVGFVLTNHWSFWILIIGLIVLVAPVTGVATLGFAIAMDERTTGSGSASSLLGLLQSLLGGLVTPLVNLKGEYNSTPYLIIISIAALALMMLQIVNYFVFKESTE
>NC_017353.1|WP_012990757.1|744311_745685_+|zinc-ribbon-domain-containing-protein
MTTCPKCGEEIKNEQTNHCPNCGATINDNGENSSNQASNEATIRLKKIVPWAIGGFIIILLIIVFVLLKNFNSPDAQAKILINAIDNDDSQKVATMLTTRDNKVDETEAQTYIKYIKKEVGMTKFIFDIRETVEKLNKSETRVAAYLQTRAGENVLRVSKNGRRYLIFNNMSFTPPTKEVTVKPKEDTKYEFKDDGRNKKVVAEADKETTIGKFIPGNYAIDAKKITDNGVFTGYLKFDFKYANSNTVDVNEDFNEAKVHVKIKNGEQLSRSSLKVKINDRTWDYGNAKVYGPYPKNKDITVSATGKVKGKTFETETKSIKADKLTDNTDVTVSFDDDDISDYIEKKEKEDNSLKNKLGSFFSSYSLSLNQAIAQSDFSLVHSFLKKGSSSYDKVRKNIASNTSARLVSPIILSVDQTGDTIKAKVQGFGLNGLPVVKNYVLEESKDDLGYKLVKVD
>NC_017353.1|WP_002460174.1|743752_744214_+|MarR-family-transcriptional-regulator
MSTISKSHIDFMKQFIDDVNTLTAKLFKDIQNEYGISVEQSNVLRLLSNHQALTITEITEKQGVNKAAVSRRIKKLIDAKLVCLEKPNSHIDQRLKYIKLSTKGQQYIDESKNILSRIANDMVKDFSSNEIEQALNVLCIIDSRIKQFNKQFD
>NC_017353.1|WP_002478769.1|742623_743577_-|YdcF-family-protein
MLSISIAFLTFICIVPTLFNSQTFVSLRLYFISVILAFSFVLINLWQQSFVLCYFSLFIVLVTVLFVKHFYLIKQQQGRQLLQELMKYIYRLLLFSCACAYISLIHVPVFTGLFIWFSLIAISTLTTFALYLCFSSAFGRMTNHCTFDGIIVLGAGIFTEAVTPLLASRLNRALSIYNQQSHCTIIVSGGQGKDEPISEALAMKRYLLSHGVPEQSIIMEAHSTNTAENFLYSKSIIDAMTPKPNKLLVVTSQFHILRALRFAQKFGLPVQGIGSSTPCHLLARSLIRDFLGLMHQYKLLLTLYFALLFISAILLNL
>NC_017353.1|WP_002478768.1|741864_742533_+|ABC-transporter-ATP-binding-protein
MTLKVANLRKTFGQGEAKTQVLKGIDFEIADGEFVILNGASGSGKTTLLTMLGGLLTPTEGTIEVNDKPLFSTQSHNSALRLTDIGFIFQAAYLIPYLSVIEQLTLVGKEAGQSHNDAQQRARTLLSDIGLAHRLDAYPHMLSGGEKQRVAIMRAFMNQPKIILADEPTASLDAKRAVQVVDMIKTQIKSNHMMGIMITHDERLFAYADRVIQLYDGQIVPG
>NC_017353.1|WP_002478767.1|740806_741868_+|ABC-transporter-permease
MMKLAWREITFYKFRYILITLIIILLASMVLFITGLAQGLARENISFFEQQHAQHYVMQKMSQPQLEKSNISAQDTSKVRTILQQQPTRLKPQVLTVNQDSLDVMTVTTDKTFKPQLQAGTYPKKAHDIAINNKLTAKGIQIGDKVHFKGHSTHYHVTGILENTMYAHSSMLWMTQEGFEQLNKQAATVFPVKDLNEEQRSQLADDSKLELVKPDTLQANIASYQAEQAPLNLMVMSLFVITAIVLSAFFYVMTIQKISQIGILKAIGIKTRHLLIALIGQIMLITLFGVSIAVGLIWSLTFVMPVTMPFYIHLTNILVILGGFVLVALIGALLSMIKVLKVDPIEAIGGNAS
>NC_017353.1|WP_002460180.1|740004_740679_-|response-regulator-transcription-factor
MVNCLIVDDDQTILDYVASHLNNEGYHTYTKPSGTAALQFLEQQTVDIAIVDIMMAGMDGFELCQQIKLDFDLPVIMLTARDALTDKERAFLSGTDDYVTKPFEIKELIFRIKAVLRRYQINAEHIIQLGNLTLNDNYMEVQVDHKTMTLPKKEFQLLYMLTSHPKQVFLRDTLIEKVWGFDYEGDERTLDVHIKRLRQRLSKLAANVTITTVRGQGYKVEAHV
>NC_017353.1|WP_002478774.1|751078_751786_-|hypothetical-protein
MEQSRSQHPTYQRTQYQPDYQLQTTKKRSWVSIIIHFIVLVLTAISGYSMYKQPLFIFGLKDTEVGYTQLKNFKQSLSNLSELSINSDQVTKLNGLGLSDIAKQLEALSIKPEHIEQLKSVIEQINMLFNIFFGLCILSLILTILTLLFNRTLLKLLNFLSIASMLAIVVYFMIAIDYLAQRIAKLLNNAYVQITPDQVIIEADATHNAIILLICCLALIFLSLFFRSKRQIKRL
>NC_017353.1|WP_012990759.1|751994_752903_+|alpha/beta-hydrolase
MRTYMMNRVVNKYLLHNRSIQFKDEGQFNQFMEKRRNANRLKHKQPSTLNVKSNLDKLMLDDMQVFRFNFRHETGKKILYLHGGYNTLQPSPFHWRLMDKLTLATLYEVVLPIYPKAPEFHIDDTFKAIQAVYVQLVDEVGAENIVVMGDGTGGALALSFVQSLIKQQLSMPRKLYLLSPLLDATLSNPEITEKLQQQDQFVNRQGVHDILSVWAAGKPLNNAEISPINGNLEGLPPIVMFGAGKEIYYPDMERLDFYLSEQRQPIEFFRYPKMIHDFSLFPIHESHKVVKQIAQTIDNDLR
>NC_017353.1|WP_002478776.1|752935_753325_-|hypothetical-protein
MTKSSIEKIKSYLLDLHDDLKLNLIDMNQTKDMFMNGPSTELLRRALNMSYYQGQKQALDWLQYNVESQDSHTLMTLIEDKLHLLTEQDSKVKNLAIMAKELPEQLSQEAHRDGQRSILKHIKTRIDVF
>NC_017353.1|WP_002478777.1|753330_753798_-|thioesterase-family-protein
MIFTVQGMVQQSQIDHNAHMHDADYNYIFSDAINQFNYTHGLSLAERQALHYTIFTVEEHTTYLAEMSLGEHYIIQLFIYNYDDKRIHFFLKLIKENGTLAATNEVMMLGIDSTTRKAAAFPEPYFTEMTSYYKTQDISQWPKQLGHQIGIPNKG
>NC_017353.1|WP_002478778.1|753916_754864_+|magnesium/cobalt-transporter-CorA
MSITIRYQTPHTSLTTVPDIADVPKDATIVWYDFEDATAKENDFLRENFDFNYLEIDDTITGVPRVKYKAYDDYQYIVFHSINSDDYSPRALNVFLKNNVLVTYHHKHFSSLMKVAKWNAYHHDGELDCADIVIHILDMMVDKYFDFVYDIEEKVYNFEDKHVDDALSKKVMDNVFKLRSDLIKIKRVMFPMQELVETIKSEGNLIVDSKHSMYIQHIDDHLIKQSNIIRTSQEMTNEIRENYESYSSFRMNSIMQILTLVSVIFSPLTFIAGVYGMNFDNMPELRWHYSYYICLVVMLVIAIALIIFFRKKRWF
>NC_017353.1|WP_002460158.1|754909_755962_+|type-2-isopentenyl-diphosphate-Delta-isomerase
MSNFQREQRKNEHVEIAMAQQDAPASDFDRVRFVHHSIPHIDVAQVNLSTHTSNFKLDYPLYINAMTGGSEWTKQINEKLATVARETGLAMAVGSTHAALRNPDMIESFRIARQVNPEGVIFSNVGADVPVERAVEAVELMEAQALQIHVNAPQELVMPEGNRTFASWMDNIAKMINHVPVPVIIKEVGFGFSKETFKALKDIGVTYVDVSGRGGTNFVSIENERRSNKDMNYLANWGQSTVESLLESQAYQSSLNIFASGGIRTPLDAIKSLALGAKAVGMSRPFLNHVENEGVEQTITFVAQFTTQMQQIMTMLNAPDIEALKQSQLIFDQQLLSWMEQRHIDIDRGL
>NC_017353.1|WP_002478779.1|756086_756695_-|DNA-3-methyladenine-glycosylase
MDFIVPSTIDTAKALLGVKVIYNDDGQIYSGYIVETEAYLGFDDRAAHGFGGKQTPKVTSLYQRGGTIYGHIMHTHLLINFVTQQAGVPEGVLIRAIEPVDGIEAMKINRGKYGYELTNGPGKWTKAFHIPRAIDGTLLNVGRLSIDTKNRKYPREIEASARIGIPNKGIWTSKPLRYTVKGNPYVSRIPKKNMRAAIDTWK
>NC_017353.1|WP_037540600.1|756953_757148_+|helix-turn-helix-transcriptional-regulator
MNKVKVYRGYSKISQLELARAVGVSRQTINMIENGKYNPSLKLCVNIAKTLGTTLDTLFWENDT
>NC_017353.1|WP_002478780.1|757702_758713_+|aldose-1-epimerase
MIVEVEKQRHGIDLIKIDNNETSIVFSNYGARIVAWKFHDNNIVLGNRVEADEFYLNNPLKFGATIGRYSGRIEAGAFKLNQDRYQLEQNDGLNHIHGGSNGCDQVLFDYDIVEGISDVKVIFRAKLNASDDGYPGDLALKVIHHYDIEHRWTITYEAETTATTIFNPTNHVYFNLNRDNNVIDNHQIHAKDLKMYLLNRQHFLLNDTPINLASQFGSDHITFQKIFQAHQDDIKQQMERYQGLDHPFELSEQTLSVENGEFKLQIDTDMPYVVIYTMNHPETWESQLNIYKPHSGFTLETQFLPNDINYFGQQAPSILRAGQQFSSTTSYQISEQ
>NC_017353.1|WP_002478781.1|758788_759442_-|MOSC-domain-containing-protein
MIPVVAISTGKIQHLPYSTKKPMISALDKIPFTGRMWLSIDGFSEDEQAYKDHGGPHKAVCCFSQSNYDMYKEDLAQLPTYAMFGENVTVKHLDERDVYFGNQYRLGEAILEVSEMREPCWKIQAKYQIPDLVKRMTASGKTGFYFRVIQEGYVSQEDNLELLTQANKASRLSVYELNDIYYNDRKNISRISYALNNPYLSPSRREKLSRLYHRACK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017353_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017353_7

786743-786822

Orphan

Consensus_repeat	Method
TCGATCAAAGCAAGTTGGGGTGG	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NC_017353_7

>merge|NC_017353|7|786743-786822|CRISPRCasFinder
TCGATCAAAGCAAGTTGGGGTGGGGCCCCAACAGAGAGAAATACGAAAAGCATTTCGTCGATCAAAGCAAGTTGGGGTGG

>NC_017353|7|6|786743-786822|CRISPRCasFinder
TCGATCAAAGCAAGTTGGGGTGG	GGCCCCAACAGAGAGAAATACGAAAAGCATTTCG
TCGATCAAAGCAAGTTGGGGTGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017353.1\|WP_002478794.1\|779591_780368_+\|inositol-monophosphatase-family-protein	unknown	unknown	gnl\|CDD\|238815
NC_017353.1\|WP_002478800.1\|789175_789712_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NC_017353.1\|WP_002460124.1\|784690_785161_+\|DUF1641-domain-containing-protein	unknown	unknown	gnl\|CDD\|225283
NC_017353.1\|WP_002478796.1\|785596_786370_+\|glucosaminidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|226656
NC_017353.1\|WP_002478792.1\|776409_777297_-\|N-acetylmuramic-acid-6-phosphate-etherase	unknown	unknown	gnl\|CDD\|235467
NC_017353.1\|WP_002478803.1\|791780_793172_+\|Na+/H+-antiporter-NhaC	unknown	unknown	gnl\|CDD\|188097
NC_017353.1\|WP_002478791.1\|775007_776396_-\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|181971
NC_017353.1\|WP_002478799.1\|788430_788763_-\|multidrug-resistance-protein-SMR	unknown	unknown	gnl\|CDD\|224987
NC_017353.1\|WP_002478804.1\|793882_794620_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NC_017353.1\|WP_002460129.1\|777293_778343_-\|DUF871-family-protein	unknown	unknown	gnl\|CDD\|377567
NC_017353.1\|WP_002478805.1\|795189_797166_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NC_017353.1\|WP_002478798.1\|788116_788431_-\|multidrug-efflux-SMR-transporter	unknown	unknown	gnl\|CDD\|224987
NC_017353.1\|WP_002460126.1\|780486_781437_+\|LCP-family-protein	unknown	unknown	gnl\|CDD\|181811
NC_017353.1\|WP_002478793.1\|778511_779201_-\|HTH-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NC_017353.1\|WP_002478802.1\|790664_791738_+\|NAD/NADP-octopine/nopaline-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|376763
NC_017353.1\|WP_002478806.1\|797202_797943_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_017353.1\|WP_002478801.1\|790010_790433_-\|DUF4870-domain-containing-protein	unknown	unknown	gnl\|CDD\|225833
NC_017353.1\|WP_002492284.1\|787094_788048_-\|2-hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|240655
NC_017353.1\|WP_002460123.1\|785343_785577_+\|hypothetical-protein	unknown	unknown	unknown
NC_017353.1\|WP_014533231.1\|781736_784691_+\|formate-dehydrogenase-subunit-alpha	unknown	unknown	gnl\|CDD\|225918

Protein	Function_ID	Function_description	E-value
NC_017353.1\|WP_002478794.1\|779591_780368_+\|inositol-monophosphatase-family-protein	gnl\|CDD\|238815	cd01637, IMPase_like, Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1,6-bisphosphate, inositol poly- and monophosphates, PAP and PAPS, sedoheptulose-1,7-bisphosphate and probably others.	2.83764e-70
NC_017353.1\|WP_002478800.1\|789175_789712_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	9.90228e-33
NC_017353.1\|WP_002460124.1\|784690_785161_+\|DUF1641-domain-containing-protein	gnl\|CDD\|225283	COG2427, COG2427, Uncharacterized conserved protein [Function unknown].	1.85067e-26
NC_017353.1\|WP_002478796.1\|785596_786370_+\|glucosaminidase-domain-containing-protein	gnl\|CDD\|226656	COG4193, LytD, Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism].	4.35673e-77
NC_017353.1\|WP_002478792.1\|776409_777297_-\|N-acetylmuramic-acid-6-phosphate-etherase	gnl\|CDD\|235467	PRK05441, murQ, N-acetylmuramic acid-6-phosphate etherase; Reviewed.	3.78745e-173
NC_017353.1\|WP_002478803.1\|791780_793172_+\|Na+/H+-antiporter-NhaC	gnl\|CDD\|188097	TIGR00931, Uncharacterized_Na+/H+_antiporter_HI_1107, Na+/H+ antiporter NhaC. A single member of the NhaC family, a protein from Bacillus firmus, has been functionally characterized.It is involved in pH homeostasis and sodium extrusion. Members of the NhaC family are found in both Gram-negative bacteria and Gram-positive bacteria. Intriguingly, archaeal homolog ArcD (just outside boundaries of family) has been identified as an arginine/ornithine antiporter. [Transport and binding proteins, Cations and iron carrying compounds].	1.20653e-120
NC_017353.1\|WP_002478791.1\|775007_776396_-\|PTS-transporter-subunit-EIIC	gnl\|CDD\|181971	PRK09586, murP, PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed.	3.2639e-102
NC_017353.1\|WP_002478799.1\|788430_788763_-\|multidrug-resistance-protein-SMR	gnl\|CDD\|224987	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism].	7.07691e-20
NC_017353.1\|WP_002478804.1\|793882_794620_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	5.5132e-32
NC_017353.1\|WP_002460129.1\|777293_778343_-\|DUF871-family-protein	gnl\|CDD\|377567	pfam05913, DUF871, Bacterial protein of unknown function (DUF871). This family consists of several conserved hypothetical proteins from bacteria and archaea. The function of this family is unknown.	1.19472e-94
NC_017353.1\|WP_002478805.1\|795189_797166_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	7.03158e-16
NC_017353.1\|WP_002478798.1\|788116_788431_-\|multidrug-efflux-SMR-transporter	gnl\|CDD\|224987	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism].	4.36019e-24
NC_017353.1\|WP_002478793.1\|778511_779201_-\|HTH-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	2.43763e-29
NC_017353.1\|WP_002478802.1\|790664_791738_+\|NAD/NADP-octopine/nopaline-dehydrogenase-family-protein	gnl\|CDD\|376763	pfam02317, Octopine_DH, NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain. This group of enzymes act on the CH-NH substrate bond using NAD(+) or NADP(+) as an acceptor. The Pfam family consists mainly of octopine and nopaline dehydrogenases from Ti plasmids.	1.26055e-49
NC_017353.1\|WP_002478806.1\|797202_797943_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.27042e-09
NC_017353.1\|WP_002478801.1\|790010_790433_-\|DUF4870-domain-containing-protein	gnl\|CDD\|225833	COG3296, COG3296, Uncharacterized protein conserved in bacteria [Function unknown].	3.76647e-25
NC_017353.1\|WP_002492284.1\|787094_788048_-\|2-hydroxyacid-dehydrogenase	gnl\|CDD\|240655	cd12178, 2-Hacid_dh_13, Putative D-isomer specific 2-hydroxyacid dehydrogenases, NAD-binding and catalytic domains. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	0
NC_017353.1\|WP_002460126.1\|780486_781437_+\|LCP-family-protein	gnl\|CDD\|181811	PRK09379, PRK09379, LytR family transcriptional regulator.	1.04716e-92
NC_017353.1\|WP_014533231.1\|781736_784691_+\|formate-dehydrogenase-subunit-alpha	gnl\|CDD\|225918	COG3383, COG3383, Uncharacterized anaerobic dehydrogenase [General function prediction only].	0

>NC_017353.1|WP_002478796.1|785596_786370_+|glucosaminidase-domain-containing-protein
MRKKRKKLKKHYIITILAITSILLLYKGQLFFISNQQVTFDEAVRLQTSSEMINTINNNGEFTAANRHQVESAMRISFRDTEFKYMELTHPIKMSEKEVNQMLHNKGILDGHGQQFLAAQKQYKINVIYLVSHALVETGEGQSTLAKGITDGQQRYYNFFGIGAFDSNAIQTGKSYAKTHHWTSPNKAIIDGASFIRSHYFDQGQVSLYQMRWNPANPAHHQYATDIYWDEQIANYMAHFYKQYGIKKDRIQRDFYR
>NC_017353.1|WP_002460123.1|785343_785577_+|hypothetical-protein
MIKRIMIASNLCLVAGLICLFIMQFMLAISMFAISLTMSLVLFNVLLRERKGLKWAINGSFLFVVLVIVVAYFIMTK
>NC_017353.1|WP_002460124.1|784690_785161_+|DUF1641-domain-containing-protein
MAERITNIKRLKKSDEQIKLENLTEVTDAIADNKDSILKAIKLIKVLDDAKLLDALNGAIKGRQVIINKFAVELNKDIYTGLLSNMASLVFLLGDLEVKDLSAFLAKVNKGLHVANQASPNAKTSIRHLLGVLKDDDMNRSLTYMLNMLKGMSREH
>NC_017353.1|WP_014533231.1|781736_784691_+|formate-dehydrogenase-subunit-alpha
MQEHLIVTLDDTDYLVEPGTNLLEFIKSRNTFVPSICYNESMGPIQTCDTCMVEIDGQIERACSTTIDRPMTVNTENNEVKSSQKEALDRILEKHMLYCTVCDYNNGDCEIHNTMDEWGLQHQTYEYKEKPYEKDYGPFYRYDPNQCILCGRCVEACQDIEVNETIRIDWDREHPRVIWDNDVPINESSCVSCGQCATVCPCNAMMEVNMEGNAGYMTDTEPGSLAAMIDLTKKAEPGYGPLFAISDSEAEMRKERINKTKTVCTYCGVGCSFEVWTKDREVLKVQPSHDSPANKVATCVKGKFSWGHINSDQRLTKPLVRKNGEFHEVEWDEALKVVVDNFSQIKNQYGGEALAFIASSKGTNEESYLMQKLSRQVFGSNNVDNCSRYCQAPATKGLFRTVGHGGDSGSIEDLEKAAMTVLIGTNTAEAHPVIASRMKRAQKLFGQRSHVFDIRKHEMAERADEFYQPKPGTDLVWLGAATKYIIDHDLHDKAFIDEWVDNFDDYYTSLEPFTMEFAEEATGIPKERLIKFAEEAAKAETVAICWAMGITQQDIGSDSSTAISNFLLATGNYRKPGSGAYPLRGHNNVQGASDMGSMPDQFTGYQRVVDDDVRAKFEKEYGVTLNPTPGRDNHQMMEGIHNDEIHSLYLYGEDTGIVDSNINFVQSALEKVDFLVVQDEFLTFTASYADVVLPASPSLEKDGTFTNTERRIQRINQALTPLGDSKPDWVIFQMIAKEFGFDWNYNYPGDIMDEIARLTPLYAGVSYDRLQGFDSLQWPVHEDGTDEPLLYLEGFNFENKKAKFYPLSFDNFFKEDEVYDLHVNNGRLLEHFHEGNMTYQTEMIKYKMPNTFVEISPELAKDRNIHEGAEVKLISTTGEAKLIVHVTDRVKGKEIYIPLNNDAMVHGDMGAINLLTNSDVDQYTDTPSYKRTSCRMEILSRRGKSPLNPTNFRVDKQRHPQYSVQVQKKWERQDYVFPGNKGDQ
>NC_017353.1|WP_002460126.1|780486_781437_+|LCP-family-protein
MRRSERKKMNLPLKIFLWMFGILVLLAIIAVIYVAAKIFITGDKIHNPLDRSHSALRSKNVNLSKGEPFTIALFGVDSDAKRKQANDGQRSDTIMILSINPSKQKTDIVSIPRDTKADIVGRGTTEKINHAYAYGGANMAVKSLEKLMNVPIDHYATIDMDGLHDMIDALGGVDVVSNDTFTINGTHFVHGEKTHLDGDKAMNFIRSRKEEGAGGDFGRQERQQIILQAMANKMVSKSSITHFNSLLSEIQKNVKTDLSLSEMNQIRSNYKGANKTVNRYQLDGQGGIQDDGLYYFIPSESSKKDSTDIINSNLGL
>NC_017353.1|WP_002478794.1|779591_780368_+|inositol-monophosphatase-family-protein
MHKRLEEIDQLIERWIQQLDVIIPQLLAKLDTDIKQDRFDLVTNVDKALQQHFSEMLHEHLPGHQLVAEEKNNDTISAHEGHVWLLDPIDGTANLVKQQEDYCIIIGYFVNGKPKLSYIYDYVHQKLYKAIEHRGAFENNNPLPKPPILSLQDAMISFDAQYIPVDVSKALREACFANRNIGSCGLDSIKVIKGQFGAYINTNPKPWDIAAQHLFAKELGLKMTCLTRAALNIAEAGPFIISNEGCYDEIINIYQRYS
>NC_017353.1|WP_002478793.1|778511_779201_-|HTH-domain-containing-protein
MNKAERQNQLIHVIQQNRKMTASELATALNVSKRTISRDIAELEEQGVRIFAQHGKLGGFQIQQSQSKMALSISEEQLLALFLTLNESQSYSSLPYKQEIQEIIQQCLKLPNTRVRKLLKRMDKYIKFDTIEATPLPKLFSDILIYSAERNVMSVDFVSDNKMAAQNVIFIGILCKNAEWLAIVFDIGHGCTRELPILAIHDISYSFEKTLNTHDITIDNYTQFLNPSD
>NC_017353.1|WP_002460129.1|777293_778343_-|DUF871-family-protein
MVGFSVYLGTTLNKTYIHKMTQLGYDMIFTSLQLSKLSLRQQLAYLGELCELLRNVNMTYVIDVHPDLLNHDFFTFFNNISTGNFIIRIDNQLQISMIEELQNHGLKCCLNASTIDASILQQLPTKQPIYYCHNYYPRPDTGLSTDFVSAQNHLIRQFDSNSIIFAFIPGSEFRGPLYCGLPTIEQHRTNNPLLAATQLMNSGINNIIISDPYMTAKHAEQLIFMLRDRHFKLKVTKLEHSYQQLLLQQHTSRPDAPEHVIRSSESRSRCQQHITSQPYPFDIRSCGHVTIDNHLNGRYEGEIQIVRTPLPTHSHVNYLATIVAEDQVLLPLIQPNDTFEFIEDKGVNQ
>NC_017353.1|WP_002478792.1|776409_777297_-|N-acetylmuramic-acid-6-phosphate-etherase
MKHLMTERRNKRTMHLDDMPILEALKTINSEDHQVAIAVQQILPELSKAIETIIHQFSKGGRLIYIGAGTSGRLGVLDAAECVPTFNTSPGEVIGLIAGGQGAMTTAIEGAEDSASLGEQDLKNINLNKQDVVVGISASGRTPYVISALTYANQLEAKTVALSCNVNSDISQLADYALEVNVGPEVLTGSTRLKAGTSQKLVLNMISTMTMIGIGKVYDNLMVDLKPTNTKLQQRSIHIIEDICSIDHETAQHLYQQANNDIKVAVVMHMCDTSRNDAQLRLTKHNGVIKKAIQS
>NC_017353.1|WP_002478791.1|775007_776396_-|PTS-transporter-subunit-EIIC
MKNEQQLAEQILHAVGGIENINDILHCMTRIRLKLNNKQHVNYTELKSIKGVLGVIDDDRLQIVLGPGVVDKVTEYIEKQHKTTSSPAQPTENKQHKNSNKRWNKVLRTIADIFIPLIPAFVGAGLVGGIAAVLNIFIQAGDLTADWVKQMVVVLNVIKDGMFFYLAIFTGINAAKVFGATPGLGGVIGGTTLLTGISDKNPIVNIFTGEPLLPGQGGIIGVIIAVWLLSLIEKRLHKIVPNAIDIIITPTLTLLIIGLLTIFVIMPLAGFISSGLVIVVNWVIDIGGIFSGFIIGASFLPLVMLGLHHIFTPIHIELINQTGATNLLPIAAMAGAGQVGAALALWMRCKRNKQLANVIKGALPAGFLGIGEPLIYGVTLPLGRPFFTACLGGGIGGAVIGGIGHIGARAIGPSGLSLLPLISNHMYLGYLIGLISAYIGGFILTYFFGTTKSMRNSTQLGG
>NC_017353.1|WP_002492284.1|787094_788048_-|2-hydroxyacid-dehydrogenase
MEKVYIAGKIPEVGLNLLKEHFEVEMYEGEGIIDKETLKRGVKDASALISILSTNVDKEVIDAANNLKIIANYGAGFNNVDVDYAREKNIDVTNTPKASTNATAELTFGLVLAVARRIVEGDKLSRTQGFDGWAPLFFRGREVSGKTIGIIGLGEIGGAVAKRAKAFDMDILYTGPHQKVEKEREIGAKYVDLETLLKNSDFITINAAYSPKLHHLIDTEQFKLMKSTAYLVNAGRGPIVNEEALVQALHDKEIEGAALDVYEFEPKITEGLKSLDNVVITPHIGNATYEARDMMSKIVANDTIKKLTGETPQFIVN
>NC_017353.1|WP_002478798.1|788116_788431_-|multidrug-efflux-SMR-transporter
MSWFYLIIAGCFEILGVVLLNQLARTSRWYYIILLALTFVLSFTTLKLAMVSIPMGTAYAIWTGIGTAGGTFIGMLFYQESTHPLRIGFIAVIIAAVIGLRLLG
>NC_017353.1|WP_002478799.1|788430_788763_-|multidrug-resistance-protein-SMR
MTWLKVIMAGLLEIVWVTSLNQAHSLTSWSFTLLMIALSFYLVISATKSLAVGTVYALFVGIGAAGTVIVDMLFFHQPISILKLILILMLIIGILGLKLTTDITEHGGSN
>NC_017353.1|WP_002478800.1|789175_789712_-|CHAP-domain-containing-protein
MKKLLTITTLTAGLGATLISTSHQADAAEFQPSHQYSYQQQNFSQQAYQYHTTETNTTSTSTSTQSISTSSGNLYTAGQCTWYVFDRVDGKIGSTWGNANNWASAAQAAGYTVDHQPEEGAILQTSEGSYGHVAYVESVNSDGSVTISEMNYSNGPFSTDTRTISASQASAYNYIHLN
>NC_017353.1|WP_002478801.1|790010_790433_-|DUF4870-domain-containing-protein
MTQQSQGFNTPQHNDSDDVRLMAMLIYLLGFVSGFIGPLIIWLVKKDDSKLIDQSGKSYLNMFISYMIWCAVPVVIMMFSLIFYMPFDPTSGLISIFIFLLLNLVILGLLITFSVFNIIGCVKYYQGTYYQAPLSIRFFK
>NC_017353.1|WP_002478802.1|790664_791738_+|NAD/NADP-octopine/nopaline-dehydrogenase-family-protein
MKIAIIGSGNGAVTAALDMVDQGHEVRLYCRNQSLEKFNTAFERGGFDFNNEGNEKFIEFTNISDDIAYVLQDAELVQVIIPSSFIEYYAKVMSYHVTNDHLIFFNIAASMGSIRFMNVLEDRNIDVHPKFAEANTLTYGTRVDFAQARVDLSLNVRRVYFSTFNREELNDSYDKVSQIYPQLVKEESLLKTNLENGNPEVHPGPTLLNVGRIDHAQKFSLYKEGITQHTVRLLHAIELERINLGRRLGFELESAKESRIQRGYLERTDEDEPLNRLFNTSPVFSQIPGPNHVENRYLTEDIAYGLVLWSSIGRVIDVPTPNIDAVIIIASTILERDFFEDGLTVEELGLEKLDLSY
>NC_017353.1|WP_002478803.1|791780_793172_+|Na+/H+-antiporter-NhaC
MTRKPTFFEALSTIIVMVCVVTIGFIVFNIPIQVLLLISSAYAALIGIRVGLKWNDIEEGITHRLTTAMPAIFIILAVGIIVGSWMYAGTVPALIYYGLKFLNPQYFLVSAFIISAICSLATGTAWGSASTAGIALISIASQLNMNLGMAAGAIIAGAVFGDKMSPLSDTTNLAALVTKVNIFSHIRAMMWTTIPASLIGMIVWFVLGLHNDGHVNTKQIQSLLSELATLYQFNFFVWIPLIVIIICLMFKVSTVPSMLASSITAIFVGAFNHHFNLADGFKATFDGFTANMTGHSHISHNAKTLIEQGGMMSMTQIIVTIFCGYAFAGILEKSGCLNVLLETISKGVKSTGSLILITVICCLMMVFAAGVASIVIIMVGVVMKDMFEDMGLDRSNLSRTLEDASTMVLPLIPWGTSGIYYAQQLNVPVDQFFIWTVPCYLCAILAVFYGFTGIGIKKNNKVT
>NC_017353.1|WP_002478804.1|793882_794620_-|CHAP-domain-containing-protein
MKKIATATIATAGIATFALTGGHHAHAAEQTNHDGYNPNDPYSYSYSYTIDAQGNYHYTWKGNWSPNQLNQNQGYTYYNNYNSYYNYNNYNYSNTYASSNSYRTGGLGASYSTSSSNIHVTTTSAPSSHGVSISSASHSGSNLYTSGQCTYYVFDRVGGKIGSTWGNASNWANAAAAAGYTVNNRPSVGAIMQTSQGYYGHVAYVESVGSNGSVTVSEMNYGHGPGVVTTRTISASQAASYNFIH
>NC_017353.1|WP_002478805.1|795189_797166_+|helix-turn-helix-transcriptional-regulator
MNGQFSVKLLQKLNTYGQKTVNVKLIYWVKGQGTIDINLKQYHMTEGDIVLLMLNDLYQIQSDDDAVTLVVDLSFKDYVKYASEYIDISGYKLSNIEKQQVLPILMNIIELECFNKADEQTTLKMIKHLCVELGSMSHLYRAKTQNMTVLDEVHDYLISHHTKKLKKQEIANALNMTNQELSNVIKYQTPFQSINQYVNDIRLKCALIDILKEHRTVEDIAYQHGFNHYSRFINLFKDSYGYTPKEIRKQYHSLTTSYYENIQYLPLSEQTYQSYFHKVKHYTTVSNNKDIILSSNTLPICHIEPKDLFITSQQLLYLNEHQIFYVTQHLFSKNKHVYVIIPFDLTDFSAVQRMCEYYLTKLNYLGLTPIFYFKGLDLTYLEQHGFNNVNQLFITLFYSRFVNEVDGVSIMLDSTDKQVIQKVVNEVRQFFNRCTLYLSVPHRDVRPYEFNEIDEYITSYFITFEQLTTWKKYHHKVILDTTMLNMNQNGEITQQNIINFSLMARYYLMLKGISFSLDFLLQYLFHGRNMDNNMFLAFFNMMNQLRGDIVHQDNQIILTKFKFEYQCLAFNMNISTAEQLQDLQLNFKTTQPMSHAESSLITYTKAPNLNHHQDQTKNKDNLFQPHFWKGQLSYPTIINRKYILPSMSIGHIKFSLRS
>NC_017353.1|WP_002478806.1|797202_797943_+|MarR-family-transcriptional-regulator
MNINTRIRLVLGCYSLVKTVNESLRYAYHMNMQQFKILLFIKDYSTAHERPLTIQTLVIKEHCNKAMMLKHLAQLYAMHWISKKRNPNDQRRLIIYMTKIQHKKIEHLLQEIKKIIANYDIDAKLDLHCHFKLKEFMDVKVLHDDFELTSLHDSIHLDELFILGLIYLYPNAYNMAQLKYVIEQHNMYITPLIKSLVDKKYIYKERCRTDERQIRIGIKTDKLSQVKLLFNECYNTIVNHLELTHI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017353_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017353_8

1307010-1307100

Orphan

Consensus_repeat	Method
AAACTCGTCATGCTCGTTAAGTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017353_8

>merge|NC_017353|8|1307010-1307100|CRISPRCasFinder
AAACTCGTCATGCTCGTTAAGTGCAATAAAGGAATACCTGAGCTGAAGCTCATGCATAAGAAGCACTAAACTCGCCATGCTCGTTAAGTGC

>NC_017353|8|7|1307010-1307100|CRISPRCasFinder
AAACTCGTCATGCTCGTTAAGTGC	AATAAAGGAATACCTGAGCTGAAGCTCATGCATAAGAAGCACT
AAACTCGCCATGCTCGTTAAGTGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_017353.1\|WP_002458892.1\|1319465_1320959_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|223903
NC_017353.1\|WP_002478058.1\|1315784_1316705_+\|primosomal-protein-DnaI	unknown	unknown	gnl\|CDD\|236353
NC_017353.1\|WP_002458875.1\|1296525_1297494_+\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NC_017353.1\|WP_002458873.1\|1294559_1295417_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	unknown	unknown	gnl\|CDD\|235547
NC_017353.1\|WP_002458877.1\|1299825_1301184_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|236830
NC_017353.1\|WP_002458885.1\|1311437_1312439_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|236079
NC_017353.1\|WP_002478049.1\|1297511_1299272_+\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235784
NC_017353.1\|WP_002478048.1\|1295418_1296363_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	unknown	unknown	gnl\|CDD\|235580
NC_017353.1\|WP_002478047.1\|1293241_1294471_+\|NAD-dependent-malic-enzyme-4	unknown	unknown	gnl\|CDD\|235976
NC_017353.1\|WP_002458878.1\|1301525_1302644_+\|citrate-synthase	unknown	unknown	gnl\|CDD\|184468
NC_017353.1\|WP_002478052.1\|1304163_1304874_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_017353.1\|WP_002478054.1\|1309797_1310670_+\|bifunctional-DNA-formamidopyrimidine-glycosylase/DNA-(apurinic-or-apyrimidinic-site)-lyase	unknown	unknown	gnl\|CDD\|223344
NC_017353.1\|WP_002458881.1\|1304873_1306583_+\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|274368
NC_017353.1\|WP_002478056.1\|1312613_1313621_+\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|235755
NC_017353.1\|WP_002478051.1\|1302691_1303960_+\|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl\|CDD\|180792
NC_017353.1\|WP_002458891.1\|1317064_1319002_+\|threonine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234752
NC_017353.1\|WP_002478057.1\|1314408_1315785_+\|DnaD-domain-protein	unknown	unknown	gnl\|CDD\|226138
NC_017353.1\|WP_002478055.1\|1310685_1311291_+\|dephospho-CoA-kinase	unknown	unknown	gnl\|CDD\|234620
NC_017353.1\|WP_002478053.1\|1307147_1309781_+\|DNA-polymerase-I	unknown	unknown	gnl\|CDD\|235591
NC_017353.1\|WP_002458887.1\|1313937_1314408_+\|transcriptional-repressor-NrdR	unknown	unknown	gnl\|CDD\|234774

Protein	Function_ID	Function_description	E-value
NC_017353.1\|WP_002458892.1\|1319465_1320959_+\|amino-acid-permease	gnl\|CDD\|223903	COG0833, LysP, Amino acid transporters [Amino acid transport and metabolism].	0
NC_017353.1\|WP_002478058.1\|1315784_1316705_+\|primosomal-protein-DnaI	gnl\|CDD\|236353	PRK08939, PRK08939, primosomal protein DnaI; Reviewed.	1.56081e-165
NC_017353.1\|WP_002458875.1\|1296525_1297494_+\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NC_017353.1\|WP_002458873.1\|1294559_1295417_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	gnl\|CDD\|235547	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta.	0
NC_017353.1\|WP_002458877.1\|1299825_1301184_-\|amino-acid-permease	gnl\|CDD\|236830	PRK11049, PRK11049, D-alanine/D-serine/glycine permease; Provisional.	0
NC_017353.1\|WP_002458885.1\|1311437_1312439_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|236079	PRK07729, PRK07729, glyceraldehyde-3-phosphate dehydrogenase; Validated.	0
NC_017353.1\|WP_002478049.1\|1297511_1299272_+\|pyruvate-kinase	gnl\|CDD\|235784	PRK06354, PRK06354, pyruvate kinase; Provisional.	0
NC_017353.1\|WP_002478048.1\|1295418_1296363_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	gnl\|CDD\|235580	PRK05724, PRK05724, acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated.	0
NC_017353.1\|WP_002478047.1\|1293241_1294471_+\|NAD-dependent-malic-enzyme-4	gnl\|CDD\|235976	PRK07232, PRK07232, bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed.	0
NC_017353.1\|WP_002458878.1\|1301525_1302644_+\|citrate-synthase	gnl\|CDD\|184468	PRK14035, PRK14035, citrate synthase; Provisional.	0
NC_017353.1\|WP_002478052.1\|1304163_1304874_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.00474e-94
NC_017353.1\|WP_002478054.1\|1309797_1310670_+\|bifunctional-DNA-formamidopyrimidine-glycosylase/DNA-(apurinic-or-apyrimidinic-site)-lyase	gnl\|CDD\|223344	COG0266, Nei, Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair].	7.24117e-93
NC_017353.1\|WP_002458881.1\|1304873_1306583_+\|PAS-domain-containing-protein	gnl\|CDD\|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	8.93727e-90
NC_017353.1\|WP_002478056.1\|1312613_1313621_+\|biotin-synthase-BioB	gnl\|CDD\|235755	PRK06256, PRK06256, biotin synthase; Validated.	4.29088e-179
NC_017353.1\|WP_002478051.1\|1302691_1303960_+\|NADP-dependent-isocitrate-dehydrogenase	gnl\|CDD\|180792	PRK07006, PRK07006, isocitrate dehydrogenase; Reviewed.	0
NC_017353.1\|WP_002458891.1\|1317064_1319002_+\|threonine--tRNA-ligase	gnl\|CDD\|234752	PRK00413, thrS, threonyl-tRNA synthetase; Reviewed.	0
NC_017353.1\|WP_002478057.1\|1314408_1315785_+\|DnaD-domain-protein	gnl\|CDD\|226138	COG3611, DnaB, Replication initiation/membrane attachment protein [DNA replication, recombination, and repair].	1.01886e-90
NC_017353.1\|WP_002478055.1\|1310685_1311291_+\|dephospho-CoA-kinase	gnl\|CDD\|234620	PRK00081, coaE, dephospho-CoA kinase; Reviewed.	4.59524e-92
NC_017353.1\|WP_002478053.1\|1307147_1309781_+\|DNA-polymerase-I	gnl\|CDD\|235591	PRK05755, PRK05755, DNA polymerase I; Provisional.	0
NC_017353.1\|WP_002458887.1\|1313937_1314408_+\|transcriptional-repressor-NrdR	gnl\|CDD\|234774	PRK00464, nrdR, transcriptional repressor NrdR.	2.06202e-81

>NC_017353.1|WP_002458881.1|1304873_1306583_+|PAS-domain-containing-protein
MLKFHQRLLLLLCTITIISFIGLGAIMHHSIYQTLTDKKVADLTKKTENYSKLEEQGKTEEIKNIAKNENISVKITEGNKIIFETKSHYDINPAIDNAANPSNIIYDRADEGYHYTFKNKFSNEAIYISGIDDEMVNLQKELWKYIALIGVVVLIAIYLAVRSIKRTYIRPINEVTYATSLLADGYYHVRVPESNVKETKALFVTTNELARRLQKLNNKQKIQSNRLKTTLENIPSSVLMIDKYGEIVVANHSYYEVFGLEEKVENKDYNDFIDDKIKQLILEAFKTEKSMYNQVEVNINNVHHKYFDVSCVPILSKSKKHLQGMVVVLHDITNLKKLENLRREFVANVSHELKTPITSIKGFAETLIEGAKDDVASLDMFLNIILKESNRIESLVMDLLDLSHIEQQRELETAYVNLSELAHNTVDNLQNQAKDKNIEIIDEISPDIIFKANKNKIAQVITNLLSNAINYSLENNRVIVRVYRQQSKVYLEIQDFGIGISKEEQKHIFERFYRVDKARSRDSGGTGLGLSITKHIVEAHHGVISVKSEPNKGSTFKVTFTDNYSNNEV
>NC_017353.1|WP_002478052.1|1304163_1304874_+|response-regulator-transcription-factor
MSQKILVVDDEQSIVTLLKYNLETAGYIVEVAYDGEEALEKVEKVQPDLIVLDVMLPKKDGIEVCKTIRSDKNLVPILMLTAKDDEFDRVLGLELGADDYMTKPFSPREVVARVKAILRRSQFVNEAANDAANEEDILIENIRIRPEFFEVYKDDELLELTPKEFELLLYLIERQGRVITREHMLNSVWNYEFAGDSRIVDVHISHLRDKLEENPKQPKLIKTVRGLGYKLERPKA
>NC_017353.1|WP_002478051.1|1302691_1303960_+|NADP-dependent-isocitrate-dehydrogenase
MSAEKIVKTQDGLQVPNEPIIPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKQIVWKEVLAGQKAYDETGEWLPSETLKTIEEYLIAVKGPLTTPIGGGIRSLNVALRQQLDLFTCLRPVRWFKGVPSPVKRPQDVDMVIFRENTEDIYAGIEFKEGTEEVKKVIDFLQNEMGASNIRFPETSGIGIKPVSKEGTERLVRAAIQYAIDNGRKSVTLVHKGNIMKFTEGSFKQWGYDLAHNEFADKVFTWQQYDEIVENDGKEAANKAQERAEQQGKIIIKDSIADIFLQQILTRPAEHDVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLNKVNPSSELLSSVLMLEHLGWQEAADKITDAIESTIASKIVTYDFARLMDGATEVSTSEFADELIKNLK
>NC_017353.1|WP_002458878.1|1301525_1302644_+|citrate-synthase
MAELKKGLEGVIAAETKISSIIGSQLTYAGYDIDDLAENAEFEEIVFLLKNYRLPTEEELADLKKKLNYYMTLNPRVYKHFEEYVTDNVHPMTALRTSVSYIAHFDPNAEGESEEKILERSIRIQAKVASLVTAFARVRDGKEPLKPKAELNYAGNFLYMLRGELPTDIEVEAFNKALVLHADHELNASAFTARCAVSSLSDMYSGIVAAVGSLKGPLHGGANERVMNMLSEVKSVDQVDDYLDEKFANKEKIMGFGHRVYKEGDPRAKYLREMSRKITSETGRSELYDISIAIEKRMKEEKGLIPNVDFFSATVYHSMDIPHDLFTPIFAVSRTAGWTAHILEQYRDNRIMRPRAKYIGEKDRKYIPIEER
>NC_017353.1|WP_002458877.1|1299825_1301184_-|amino-acid-permease
MEDKLQRELSNRHVQLIAIGGAIGTGLFLGAGQTIAMTGPSILLTYILIGFMLFMFMRGLGEIIIQNTEFKSFADVTNKYIGPFAGFVTGWTYWFCWIITGMAEVTAVAKYVSFWFPQIPNWVSALFCVLILMTFNLLSARLFGELEFWFAIIKIATIVGLIVVGLVMILMAYKTQFGSASFANLYQNGIFPKGASGFFMSFQMALFSFVGIEMIGVTAGETKDPQKTIPKAINSVPLRILVFYVGALAVIMSIIPWDKVSPDDSPFVRLFALIGIPFAAGLINFVVLTAAASSCNSGIFSNSRMLFGLADQQQAPPIFRSTNKQGVPHIAIIGSSVFLLVAALLNYIFPDATLVFTYVTTISTVLFLVVWGLILWAYINYSRRNPELHKQSTYKLPGGKYMGYIILLFFVFVFALLFVNVETRRAIYFTPVWFIILGLMYYRYKQMAKKTK
>NC_017353.1|WP_002478049.1|1297511_1299272_+|pyruvate-kinase
MRKTKIVCTIGPASESEEMLEKLMKAGMNVARLNFSHGSHEEHKARIDTIRKVAKKLGKTIGILLDTKGPEIRTHDMKDGLIMLEKGKEVIVSMTQVEGTPEKFSVTYENLINDVQVGSYILLDDGLVELEVKEIDKANGEVRCEILNTGELKNKKGVNLPGVRVNLPGITDKDADDILFGIKEDVDYIAASFVRRPSDVLDIREILERENNHNITIFPKIENQEGIDNIEEILEVSDGLMVARGDMGVEIPPESVPIVQKDLIRKCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSFVNAIGVSVAHTALNLNVKAIVAATESGSTAVTISKYRPHSDIIAVTPSAHTARQLALVWGAYPVIKKGRKTTDDLLNNSVATAVETGRVTNGDLIIITAGVPTGEKGTTNMMKLHLVGDEIAKGQGVGRESVVGQSVVADDASDLEGKDLSNSIIITTSVDETLVPYIEKAAGLITEENGITSPSAIVGLEKGIPTIVGVEHATKEIKDGILITVDAAQGKIFEGYANVL
>NC_017353.1|WP_002458875.1|1296525_1297494_+|6-phosphofructokinase
MKKIAVLTSGGDSPGMNAAVRAVVRTAIYNNIEVYGIYQGYQGLLDDNIHKLELGSVGDTIQRGGTFLYSARCPQFKEAEHRKVGIDNLRKRGIEGLVVVGGDGSYRGAQRISEECPEIQTIGVPGTIDNDINGTDFTIGFDTALNTIIECVDKIRDTASSHARTFIVEVMGRDCGDLALWAGLSVGAETIMVPEVKTEIKDVAEKIESGIKRGKKHSIVMVAEGCMSGQECADELMKYINVDTRVSVLGHIQRGGSPSGTDRVLASRLGGHAVDLLIQGKSGLGVGITHNQLTATPFDEIFKISDHKFNNDIYELAKKLSI
>NC_017353.1|WP_002478048.1|1295418_1296363_+|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha
MLDFEKPLYDIKNKIESLKESQQKNDVDLQDEIDLLEASLKRETKKIYTNLKPWDRVQIARLQERPTLLDYIPHIFDAFIEFHGDRNFRDDPAMVGGIAYLNEMPVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIAKNLIEMASLTVPVIAIVIGEGGSGGALGIGVANRILMLENSTYSVISPEGAAALLWKDSSLAKMAAETMKITANDLLQLKIIDNVIEEPLGGAHRDIEIQAQHIKAAFENELAELSKLNKKQLAEDRYNKFRHIGSFVD
>NC_017353.1|WP_002458873.1|1294559_1295417_+|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta
MFKDFFNRSSKKKKYLTVQDSKQNDVPAGIMTKCPKCKKIMYTKELAENLNVCFNCDHHIALTAYKRIEAVSDEGSFQEFDKGMTSANPLDFPGYEEKIEKDQQKTDLQEAVVTGIATLENLPFGIAVMDSRFRMGSMGSVVGEKICRIIDYCTEHRLPFILFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYLTHPTTGGVSASFASVGDINLSEPKALIGFAGRRVIEQTINEKLPEDFQTAEFLLEHGQLDKVVHRKDMKETLAQILKMHQEVN
>NC_017353.1|WP_002478047.1|1293241_1294471_+|NAD-dependent-malic-enzyme-4
MSLRDDALQMHKENQGKLQVTPNVKVTNKKELSLAYSPGVAEPCKEIHEDPRTVYDYTIKRNTVAVVTDGTAVLGLGNIGAAASIPVMEGKAVLFKSFAGINGVPIALDTTDTEEIIQTVKLISPNYGGINLEDISAPRCFEIEERLKKETNIPVFHDDQHGTAIVTLAGLINALRIVDKPLSDIKIVLNGAGAAGIAICKLLDAYGVRHMIMCDSKGAIYENRPYGMNETKSFVAKFTNKDKIEGSLQDVIKEADVFIGVSIADLLTKEMVQSMSKDAIIFAMANPNPEIKPEDAKEAGAKVIGTGRSDFPNQINNVLAFPGIFRGALEVEATHINEEMKKAAVEAIANLIQPDELRPDYCIPDPFDKRVAPSVAREVARAAMETGVARIEVEPQAIYDKTMKLTDIQ
>NC_017353.1|WP_002478053.1|1307147_1309781_+|DNA-polymerase-I
MDKLVLIDGNSLSFRAFYALPLLSNKAGIHTNAIYGFAMLLEKILKEEQPNHFLVAFDAGKTTFRHEKYSEYKGGRQSTPPELSEQFPYIRQLLDAYHIKYYELENYEADDIIGTLSKQAEASGLETIIITGDRDLTQLATDHVTIYYTKKGVTDVDHYTPEFIAEKYNGLLPKQIIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFHSVEGVYNHLDEVSGKKLKENLENSKADAFMSKDLATINCDSPIKVNLKDTIMGDLNDNKDKIELFQKLEFKQLLNDIDSSASENNSETEHNFEVIHHFDNINFKKLDNAIIHFEIDGSNYLKDKILKFGLYAQNQYIVISAEDIHQYTELIEWLENDHNNKIVFDAKKTYVAAHRLEINLQHIDFDVMLASYIIDPSRTIEDVQSVVSYYNQNFVKSDIAVYGKGKKRQVPLDDVLEVHIAAIMQAIYNCKPLMSDILSDHNQMDLLNNLELPLARILADMEETGIYTDVNDLKEMQNELQEKLDNLVSEIYEAAGESFNINSPKQLGIVLFETLKLPIIKKTKTGYSTAVDVLEQLQGKHPIIDYILEYRQLSKLQSTYVEGLQKVISDDQRIHTRFNQTLAQTGRLSSIDPNLQNIPIRLEEGRKIRKAFKPTSDDYVILSADYSQIELRVLAHMTQDESLKEAFIHGDDIHAATAMKVFGVEKDQVNDLMRRQAKAVNFGIVYGISDYGLSQNLGITRKKAKAFIDDYLASFPGVKQYMTDIVKDAKANGYVETLLHRRRYIPDITSRNFNLRSFAERTAMNTPIQGSAADIIKLAMVQFDKNVRETNYHAKLLLQVHDELIFEVPKSEVQDFSEFVEEIMDNALTLAVPLLVDSSYGATWYDAK
>NC_017353.1|WP_002478054.1|1309797_1310670_+|bifunctional-DNA-formamidopyrimidine-glycosylase/DNA-(apurinic-or-apyrimidinic-site)-lyase
MPELPEVEHVKRGIEPFIINTIIKSVTFSSKVIDGKSDGKETIIKGINLDGFRQFTEGYKIYKVERRSKYINIYIEKNQECRVLISHLGMAGGFFIVNHLDEIHAPNYRKHWHVIFHLSNGKLLVYSDIRRFGEIRNVQALNNYASFKNMAPEPFDESALDHYLTYLNQPKVKHKPIKQLILDHKVIAGCGNIYACEALYRAAIHPATEVQSLNQQARQNLFLEVQAVLNEGIEYGGTSISDYRHADGKTGTMQLRLNVYKQQQCKKCGHKIEQQVIATRNSHFCPVCQK
>NC_017353.1|WP_002478055.1|1310685_1311291_+|dephospho-CoA-kinase
MPKVIGLTGGIATGKSTVSELLTAYGFKVVDADIAAREAVKKGSAGLEQIRQTFGNEAINDDGEMNRQYMGQLVFNHPDKRTELNEIVHPIVHQLMDKEKSHYLNQGYNVVMDIPLLFENELEDTVDEVWLVYTSESIQIDRLMERNNLSLEEAKARVYSQISIDKKSRMADIVIDNLGDKLELKQNVERILTDQGYINQE
>NC_017353.1|WP_002458885.1|1311437_1312439_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MSTNIAINGMGRIGRMVLRIALKNEALNVVAINASYPPETIAHLINYDTTHGRYDKRVEPIESGIRVEGHDIKLVSDRNPENLPWKDLEIDIVIEATGKFNHGDKAKAHIQAGAKKVLLTGPSKGGKVQMVVKGVNDQDLDTDTYDIFSNASCTTNCIGPVAKVLNDSFGIENGLMTTVHAITNDQNNIDNPHKDLRRARSCGESIIPTSTGAAKALKEVMPELNGKLHGIALRVPTQNVSLVDLVVDLKQKVTVDEVNHAFRDANLQGIIDVEEAPLVSKDYNTNPHSAVIDAKNTMVMGDNKVKVIAWYDNEWGYSNRVVEVANQLGELIK
>NC_017353.1|WP_002478056.1|1312613_1313621_+|biotin-synthase-BioB
MNLANQIINGKYLTQAECLKIYRDASLATLDLVHEAYLIRRHYFGHKVKLNMILNAKSGICSEDCGYCGQSREMKHKQRYTLVSNETICKGADVASNNKIGTYCIVMSGRGPSDKEVEHITKTVKDIKKDHPQLKICACLGLANEEQAEKLKAAGVDRYNHNINTSESYHGQVVSTHTYNERIQTLSYMKEHHISPCSGVICGMGESDEDIIDMAFALKKIDADSIPVNFLHPIQGTKFGSMDDLTPMKCLRILSIFRLINPTKEIRVAGGREVNLQSLQPLALQIANSIFVGDYLITGGQPNELDYQMLEDLGFEIDYGNDDEITFSHPQFKSK
>NC_017353.1|WP_002458887.1|1313937_1314408_+|transcriptional-repressor-NrdR
MKCPKCSSTHSKVVDSRHADEANAIRRRRECEKCGTRFTTFEHIEVSPLIVVKKDGTREQFLREKILNGLVRSCEKRPVRYQQLEDITNKVEWQLRDEGHTEISSRDIGEHVMNLLMHVDQVSYVRFASVYKEFKDVDQLLASMQGILNDNKRSDS
>NC_017353.1|WP_002478057.1|1314408_1315785_+|DnaD-domain-protein
MTMQAYQFDLRPRDSFEVIRHFELSQAHLEILNRLYAPLIGTHAIGLYHYLNQFVSENNQELLTHYTIMNELKVNLLDFRKTMDYLEGIGLLKSFVRHQSDNSNFIYELIQPPTAYQFFNDPMLSVFLFSEVDKKRFVQLKQYFEQDRKDLTNYQNITHKFTEVFKMPNKDIKIDSQNIKSSQYYKGLDLSNEHFDFELLKELLQHHFISSEIVTDEAKALILQLATLYGLTVEAMKRMILNSITSAQTLSFEELRKQARSYYLIEHEQQLPKLAINADKYYDSESQHTRDNSTNTKQDEWLSSLDNISPVDMLSSWSGSEPTHQQKLMIEELVSREKLPLGVINILLQFVMLKNEMMLPKKYIFEVASNWKKLGISNAKEAYERALKMNEPKQVERKPQNAKNRYYGKQIVSREKTPKWLENRDTAKRQEKIKKKDDNLEKDRQQFLEQLKKDWGDD
>NC_017353.1|WP_002478058.1|1315784_1316705_+|primosomal-protein-DnaI
MKSFKNIMGSDSNLEQRISQIKQQVINDSDVKQFLTMHQSELTNAMIDRDLNVLQEFKDQQKHYDGHDYHSCPNFVKGHIPELYVEDERIKIKYLPCPCKIKYDEARFDSQLVTSHHMQRDTLNAKLNDIFTEDRDRLEIAIKANHICKSIINGKSVKGLYIYGPFGTGKSFILGAMANQLKSQKVASTIVYLPEYIRSLKNGFKDGSYEQRLARIREAGILMLDDIGAEEVTPWVRDEIIGPLLHYRMVQELPTFFSSNLSFEELEHHLSITREGAEKTKAARIIERIKSLADDVYLEGKNYRNN
>NC_017353.1|WP_002458891.1|1317064_1319002_+|threonine--tRNA-ligase
MTKINIQFPDGNKKAFDKGITTEEIAQSISPGLRKKAVAGKFNQQLIDLARPLEEDGEIEIVTPGSEEALEVLRHSTAHLMANALKRLYGNVQFGVGPVIEGGFYYDFDMENKISSDDFEKIEKMMKQIVNENHKIERKVVSREEAKEFFKDDPYKLELIDAIPQDEMVTLYSQGDFTDLCRGVHVPSTAKIKEFKLLSTAGAYWRGDSNNKMLQRIYGTAFFDKKDLKAHLQLLEERRERDHRKIGKDLELFTNNQLVGAGLPLWLPNGATIRREIERYIVDKEVSMGYDHVYTPVLANVDLYRTSGHWAHYRDDMFPPMKLDENEEMVLRPMNCPHHMMIYKNKPHSYRELPIRLAELGTMHRYEASGAVSGLQRVRGMTLNDSHIFVRPDQIKDEFKRVVHMIQDVYKDFGFEDYTFRLSYRDPEDKEKYMDDDDMWNKAESMLKEAVDELGLPYVEAIGEAAFYGPKLDVQVKTAMGKEETLSTAQLDFLLPERFELTYIGSDGEYHRPVVIHRGVVSTMERFVAFLTEETKGAFPTWLAPKQVEIIPVNVDLHYDYARNLQDELKSQGVRVEIDDRNEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQYGSQDQQTLERDEFIWNLVDEIRLKKHR
>NC_017353.1|WP_002458892.1|1319465_1320959_+|amino-acid-permease
MSKIESQNGGIIRGLKDRHISMIAMGGCIGTGLFMTSGGAIHDAGALGALIAYAIIGIMVFFLMTSLGEMATYLPVSGSFSTYATRFVDPSLGFALGWNYWFNWVITVAADVTIAAQVIQYWTPMAGIPAWLWSCIFLVIIFSLNSLSVRIYGESEYWFALIKVVTVIIFIAIGLLTIIGIMGGKFVGFETFTKGEGPILGGNFGGSLLSILGVFLVAGFSFQGTELIGITAGESENPERAVPKAIKQVFWRILLFYILAIFVIGMLIPYDSNALMGGDNSIATSPFTLVFKNAGLAFAASFMNAVILTSVLSAGNSGMYASTRMLYSMSKDKLAFPIFGKTNKYGVPYLSLLLTAILVIIIFLVQKVSGNAYEYIVAASGMTGFIAWVGIAVSHYRFRRAFQRQHHNKKELKYKAKWFPFGPIFAGILCVIVIIGQDVDFIKTGEFDLNRFVITYMGIPVFLVFFIYHKLRYKTKKIPLEEVDLRQDVHMNEIKHH

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017353_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017353_9

1871267-1871353

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCACCCCAACTCGCGTTGTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017353_9

>merge|NC_017353|9|1871267-1871353|CRISPRCasFinder
TGTTGGGGCCCCACCCCAACTCGCGTTGTTTGTTGGCTTTCGTTTTGAAAGCCTCTGTGTTGGGGCCCCACCCCAACTTGCGTTGTT

>NC_017353|9|8|1871267-1871353|CRISPRCasFinder
TGTTGGGGCCCCACCCCAACTCGCGTTGTT	TGTTGGCTTTCGTTTTGAAAGCCTCTG
TGTTGGGGCCCCACCCCAACTTGCGTTGTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017353.1\|WP_002478361.1\|1864973_1865429_-\|DUF4064-domain-containing-protein	unknown	unknown	gnl\|CDD\|372544
NC_017353.1\|WP_002459426.1\|1877069_1877699_-\|YkyA-family-protein	unknown	unknown	gnl\|CDD\|378419
NC_017353.1\|WP_002459422.1\|1871882_1873289_-\|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl\|CDD\|235798
NC_017353.1\|WP_002459425.1\|1875790_1876903_-\|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	unknown	unknown	gnl\|CDD\|213783
NC_017353.1\|WP_002459424.1\|1874809_1875787_-\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NC_017353.1\|WP_002478367.1\|1877836_1878388_+\|peptide-deformylase	unknown	unknown	gnl\|CDD\|234668
NC_017353.1\|WP_002459421.1\|1871391_1871679_-\|UPF0223-family-protein	unknown	unknown	gnl\|CDD\|179841
NC_017353.1\|WP_002478360.1\|1862485_1863097_+\|DUF1054-domain-containing-protein	unknown	unknown	gnl\|CDD\|377650
NC_017353.1\|WP_002459428.1\|1878822_1879041_+\|DNA-dependent-RNA-polymerase-auxiliary-subunit-epsilon-family-protein	unknown	unknown	gnl\|CDD\|184224
NC_017353.1\|WP_002459417.1\|1867749_1868562_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224098
NC_017353.1\|WP_002478365.1\|1870466_1871006_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380339
NC_017353.1\|WP_002478366.1\|1873292_1874597_-\|2-oxo-acid-dehydrogenase-subunit-E2	unknown	unknown	gnl\|CDD\|237001
NC_017353.1\|WP_002459431.1\|1881314_1881974_-\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643
NC_017353.1\|WP_002478363.1\|1866679_1867753_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270381
NC_017353.1\|WP_002459413.1\|1863358_1864711_+\|Nramp-family-divalent-metal-transporter	unknown	unknown	gnl\|CDD\|234815
NC_017353.1\|WP_002459411.1\|1861487_1862303_-\|inositol-monophosphatase-family-protein	unknown	unknown	gnl\|CDD\|238815
NC_017353.1\|WP_002478368.1\|1879040_1880720_+\|ribonuclease-J	unknown	unknown	gnl\|CDD\|223668
NC_017353.1\|WP_002493062.1\|1868567_1869365_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224097
NC_017353.1\|WP_014533325.1\|1869357_1870452_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
NC_017353.1\|WP_014533324.1\|1865560_1866607_-\|DUF4064-domain-containing-protein	unknown	unknown	gnl\|CDD\|372544

Protein	Function_ID	Function_description	E-value
NC_017353.1\|WP_002478361.1\|1864973_1865429_-\|DUF4064-domain-containing-protein	gnl\|CDD\|372544	pfam13273, DUF4064, Protein of unknown function (DUF4064).	5.59671e-06
NC_017353.1\|WP_002459426.1\|1877069_1877699_-\|YkyA-family-protein	gnl\|CDD\|378419	pfam10368, YkyA, Putative cell-wall binding lipoprotein. YkyA is a family of proteins containing a lipoprotein signal and a hydrolase domain. It is similar to cell wall binding proteins and might also be recognisable by a host immune defense system. It is thus likely to belong to pathways important for pathogenicity.	2.17942e-30
NC_017353.1\|WP_002459422.1\|1871882_1873289_-\|dihydrolipoyl-dehydrogenase	gnl\|CDD\|235798	PRK06416, PRK06416, dihydrolipoamide dehydrogenase; Reviewed.	0
NC_017353.1\|WP_002459425.1\|1875790_1876903_-\|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	gnl\|CDD\|213783	TIGR03181, PDH_E1_alph_x, pyruvate dehydrogenase E1 component, alpha subunit. Members of this protein family are the alpha subunit of the E1 component of pyruvate dehydrogenase (PDH). This model represents one branch of a larger family that E1-alpha proteins from 2-oxoisovalerate dehydrogenase, acetoin dehydrogenase, another PDH clade, etc. [Energy metabolism, Pyruvate dehydrogenase].	0
NC_017353.1\|WP_002459424.1\|1874809_1875787_-\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	0
NC_017353.1\|WP_002478367.1\|1877836_1878388_+\|peptide-deformylase	gnl\|CDD\|234668	PRK00150, def, peptide deformylase; Reviewed.	6.80213e-62
NC_017353.1\|WP_002459421.1\|1871391_1871679_-\|UPF0223-family-protein	gnl\|CDD\|179841	PRK04387, PRK04387, hypothetical protein; Provisional.	4.91032e-39
NC_017353.1\|WP_002478360.1\|1862485_1863097_+\|DUF1054-domain-containing-protein	gnl\|CDD\|377650	pfam06335, DUF1054, Protein of unknown function (DUF1054). This family consists of several hypothetical bacterial proteins of unknown function.	3.20647e-97
NC_017353.1\|WP_002459428.1\|1878822_1879041_+\|DNA-dependent-RNA-polymerase-auxiliary-subunit-epsilon-family-protein	gnl\|CDD\|184224	PRK13667, PRK13667, hypothetical protein; Provisional.	3.00943e-27
NC_017353.1\|WP_002459417.1\|1867749_1868562_-\|ABC-transporter-permease	gnl\|CDD\|224098	COG1177, PotC, ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism].	2.50919e-72
NC_017353.1\|WP_002478365.1\|1870466_1871006_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|380339	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain. This family contains transcriptional regulators containing an N-terminal XRE (Xenobiotic Response Element) family helix-turn-helix (HTH) DNA-binding domain and a C-terminal cupin domain. Included in this family is Escherichia coli transcription factor SutR (YdcN) that plays a regulatory role in sulfur utilization; it regulates a set of genes involved in the generation of sulfate and its reduction, the synthesis of cysteine, the synthesis of enzymes containing Fe-S as cofactors, and the modification of tRNA with use of sulfur-containing substrates. This family belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	4.70334e-17
NC_017353.1\|WP_002478366.1\|1873292_1874597_-\|2-oxo-acid-dehydrogenase-subunit-E2	gnl\|CDD\|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	0
NC_017353.1\|WP_002459431.1\|1881314_1881974_-\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	7.4558e-64
NC_017353.1\|WP_002478363.1\|1866679_1867753_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270381	cd13663, PBP2_PotD_PotF_like_2, The periplasmic substrate-binding component of an uncharacterized active transport system closely related to spermidine and putrescine transporters; contains the type 2 periplasmic binding fold. This group represents the periplasmic substrate-binding domain that serves as a primary polyamine receptor of an uncharacterized ABC-type transport system from gram-negative bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, as well as plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.52084e-132
NC_017353.1\|WP_002459413.1\|1863358_1864711_+\|Nramp-family-divalent-metal-transporter	gnl\|CDD\|234815	PRK00701, PRK00701, divalent metal cation transporter MntH.	0
NC_017353.1\|WP_002459411.1\|1861487_1862303_-\|inositol-monophosphatase-family-protein	gnl\|CDD\|238815	cd01637, IMPase_like, Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1,6-bisphosphate, inositol poly- and monophosphates, PAP and PAPS, sedoheptulose-1,7-bisphosphate and probably others.	1.07922e-84
NC_017353.1\|WP_002478368.1\|1879040_1880720_+\|ribonuclease-J	gnl\|CDD\|223668	COG0595, COG0595, mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair].	0
NC_017353.1\|WP_002493062.1\|1868567_1869365_-\|ABC-transporter-permease	gnl\|CDD\|224097	COG1176, PotB, ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism].	2.67852e-74
NC_017353.1\|WP_014533325.1\|1869357_1870452_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	1.00778e-167
NC_017353.1\|WP_014533324.1\|1865560_1866607_-\|DUF4064-domain-containing-protein	gnl\|CDD\|372544	pfam13273, DUF4064, Protein of unknown function (DUF4064).	1.47568e-20

>NC_017353.1|WP_002478365.1|1870466_1871006_-|helix-turn-helix-transcriptional-regulator
MDIGMKLKNLRMLKNLTQEELAERTDLTKGYISQIESQHASPSMETFLNILEVLGTRPSDFFQEKTKEKVLYTAEDQTIYDEYDKGYILKWLVTNSNEYDMEPLMLTLKPGASYKHFQPSNSDTFIYCLEGQITLSLGNQLYRANAEDALYFRANDVHQLCNNSKQNVTILIVATASYL
>NC_017353.1|WP_014533325.1|1869357_1870452_-|ABC-transporter-ATP-binding-protein
MQPLLSFKSVSKGYDDLNILDHMDLDIESGYFYTLLGPSGCGKTTILKLIAGFETPDSGEIIYQNRSIENLPANKRKVNTVFQDYALFPHLNVYDNIAFGLKLKKLSKKDIDQKVTDALKLVKLSGYEQRSINDMSGGQKQRVAIARAIVNEPEILLLDESLSALDLKLRTEMQYELRELQSRLGITFIFVTHDQEEALALSDYIFVMKDGKIQQFGTPTDIYDEPVNRFVADFIGESNIVNGTMVKDYVVNIYGQDFDCVNMGIPSGKKVEVVIRPEDISLIEAEAGLFKATVDSLLFRGVHYEICCVDRKGYEWVIQTTKKADVGSEVGLYFEPESIHIMVPGETEEEFDKRIESYEDTDDE
>NC_017353.1|WP_002493062.1|1868567_1869365_-|ABC-transporter-permease
MSNIKKILLVPYILWMIIFIILPVLLLIYFSFTDINGHFSFTNYQQIFQYKYFEMFWDSILYAALITMITLFISYPTAYFIRNAKNPNFWLLILIIPTWINLLLKTYAFIGLLSHDGLINKVLGILNVPKVDMLFTSAAFLVVASYIYIPFMILPIFNSMKSIPVNLIQASSDLGANPFTTFRKVILPLTKEGVLTGVQVTFIPSLSLFMITRLIAGNKVINIGTSIEEQFLVIQNYGMGATIAIVLIVFMALILIITKSNDERR
>NC_017353.1|WP_002459417.1|1867749_1868562_-|ABC-transporter-permease
MKWYGKLYISILLVILYVPIFFLMFYSFNSGGNMIHFEHFTFEHYQSLFKNDKLMAIIFNTIAVALLAASISTVIGTFGAIALFYLRQKKLKVTLLTLNNVLMVSSDVVIGASFLIMFTALGHFTGIGLGFGTVLASHIAFCIPIVVIVVLPQLYEMNHNILNAARDLGATESQILSRVLIPNLMPAIIGGFFMALTYSLDDFTVSFFVTGNGFSVLSVEVYAMARKGISMEVNAISTLLFVVIVIGIVGYYGIQRSLKRKPRLKRGMLR
>NC_017353.1|WP_002478363.1|1866679_1867753_-|ABC-transporter-substrate-binding-protein
MKQFLQLVCGALVIGLLCLGISHLFSGHEKAKSGKKIYVYNWGEYIDPELIKQFENQTGIEVIYETFDSNEAMEAKIKNGGTHYDVAFPSEYTVQKLKRANLLVPLNHHKLPNMRNLDPDYLDKSYDKGNQYSIPYFFGTVGILYNKQAYPDASFNHWSDLYQERYRNDVLLVDGAREIIGLSLNKLGYSLNDTNSQHLRQAEQDLKKLGPQVRGVVGDEVTMMLQQNEGNIAVVWSGVAAPLVQGSDKYNYVVPKEGSNLWFDNMVIPRTAQNKEGAYQFINFLLDAENSKKNTEWVGYATPNKAARQLLPNEIRNDHRFYPTQQEQARLEVYKDLGQRTLGNYNESFLNFKMSLK
>NC_017353.1|WP_014533324.1|1865560_1866607_-|DUF4064-domain-containing-protein
MSGEQYTQIKRPVSRLTEKILGWFSWIFLLLMTIITMFIALVSFSNDTSIQNLEATLNNNDLIQQILGNNGFNTTQFVIWLQNGIWAVIVYFIICLLISFLALISMNIRILSGILFLVASVVTLPLVLLFVTLIIPIFFFIIAIMMFARKNKVEIVPAYGYPGYDDNFDYRYNEPDYQQQPPIYDDYERHQPNDDMAYHMPQETSNSSFNEDDKYDQYPKRAIMSDYQSTDDEDEAPQVLSRQAKYHKNKYQDEFSDERAAPFNEAVVQQEPVLDKKELKAQRKQEKAEIKARKREKRKAYNQRMKEKRKNQPSAVNQRRMNYEERKQIFNHENSAKDQQESHLDDSK
>NC_017353.1|WP_002478361.1|1864973_1865429_-|DUF4064-domain-containing-protein
MKTKKELVIAWIANGLSLIFLLFNILSMLLTDEKNNVKEYEQMAKQFAGKNVTVTPELIHFIMVFFIGILAFSTILGIAATTLIKNRSLIAIFLFISAVLIGLFSMNIIAMILWLIVIVLLIVKRNQYKNDSDWHAEQYKHAEKKENPYIY
>NC_017353.1|WP_002459413.1|1863358_1864711_+|Nramp-family-divalent-metal-transporter
MNKRDTTHQPKHLSLDEINNTIKFDSNGTSSQKFLAFLGPGLLVAVGYMDPGNWITSMQGGAQFGYTLLFIILISSLSAMLLQSMTLRLGIATSHDLAQMTKHYLSKPVAIIFWIIAELAIIATDIAEVIGSAIALNLLLGIPLIVGAIITVCDVFLLLFIMKFGFRKIEAIVGTLIFTVLAIFVFEVFISSPSTTAILEGFVPHKEIITNHGILYIALGIVGATIMPHNLYLHSSIVQSRQYDRHSIKEKAQAIKYATIDSNLQLSVAFVVNCLLLVLGASLFYGVNQDQLGGFYDLYHALRTQPILGAALGAIMSTLFAVALLASGQNSTITGTLAGQIVMEGFLNISLPNWLRRLVTRAIAVIPVIICLIIFKGNEEKIEQLLVFSQVFLSIALPFSLIPLQLSTSNKQLMGPFVNKSWVNYCSWILIIVLSVLNVYLIIETFKEFI
>NC_017353.1|WP_002478360.1|1862485_1863097_+|DUF1054-domain-containing-protein
MTKYTFKQKDFKAFDVDGLDPRMEALEAHVRPQLRALGDYFADYFTSQTGETFYSHVAKHARRSVNPPKDTWVAFATNKRGYKMLPHFQIGLFKDHLFIMYGVMHETKDKAQRVKTFDKHFDTLTHLPEDYRICLDHMKPDKPLIKDLSVDELHEAIDRVKNVKKGEFFVARTLAPNDKRLKSDRAFLNFVEETFNEFIKFYA
>NC_017353.1|WP_002459411.1|1861487_1862303_-|inositol-monophosphatase-family-protein
MALYDFAKSLILEAGNNVRLMMKEKLSIETKSNPNDLVTNVDKATETYIYEAIHSNYPEHKVIGEEGHGHNIRNIDGVVWVVDPIDGTLNFVHQRENFAISIGIYYNGEAYAGFVYDVMKDALYHAKVHEGAFENNHRLEAIGTSELKSSLIGINPNWVTKPIIGPIFQPVVNRARSSRAYGSAALEIIAVAKGQLAAYITPRLQPWDFAGGLIILNEVGGKGSNLLGETLEITHPDSVLMANQTVHEELLQQFFLPHQQTLTELHAKYYK
>NC_017353.1|WP_002459421.1|1871391_1871679_-|UPF0223-family-protein
MEYQYPLDMDWTHDEMLKVIAFFNQIERYYESSVLSDQVIAHYRNFKQIVPGKAEEKQIFKEFEQNSGYNSYQVIKEATTQNKPTHIQQKNNTRT
>NC_017353.1|WP_002459422.1|1871882_1873289_-|dihydrolipoyl-dehydrogenase
MVVGDFPIETDTIVIGAGPGGYVAAIRAAQLGQKVTIVEKGNLGGVCLNVGCIPSKALLHASHRFVEAQHSENLGVIAESVSLKFDKVQEFKQSVVNKLTGGVEGLLKGNKVEIVKGEAYFVDNNSLRVMDEKSAQTYNFKNAIIATGSRPIEIPNFEFGKRVIDSTGALNLQEVPGKLVVVGGGYIGSELGTAFANFGSEVTILEGAKDILGGFEKQMTQPVKKGMKDKGIEIITEAMAKNAEETENGVKVTYEAKGEEQTIEADYVLVTVGRRPNTDELGLEELGLKFADRGLLEVDKQSRTSIDNIYAIGDIVPGLPLAHKASYEAKVAAEAISGQASEVDYIGMPAVCFTEPELAQVGYTEAQAKEEGLEYKASKFPYAANGRALSLDDTTGFVKLITLKEDDTLIGAQVAGNGASDIISELGLAIEAGMNAEDIALTVHAHPTLGEMSMEAAEKAIGLPIHTM
>NC_017353.1|WP_002478366.1|1873292_1874597_-|2-oxo-acid-dehydrogenase-subunit-E2
MAFEFRLPDIGEGIHEGEIVKWFVKAGDTIEEDDVLAEVQNDKSVVEIPSPVSGTIEEVVVDEGTVAVVGDVIVKIDAPDAEEMQFKGHDDDSSAKEEPAKEEAKAETEEAPAASASQDEEVDENRKIKAMPSVRKYAREKGVNIKAVAGSGKNGRITKEDIDNHLNGGGAQAASASNESAAASTSEETSAPQTQSVPEGDFPETTEKIPAMRRAIAKAMVNSKHTAPHVTLMDEIDVQDLWDHRKKFKEIAAEQGIKLTFLPYVVKALVSALKKYPALNTSFNEEAGEIVHKHYWNIGIAADTDRGLLVPVVKNADRKSIFQISDEINELAVKARDGKLTSEEMKGATCTISNIGSAGGQWFTPVINHPEVAILGIGRIAQKPIVKDGEIVAAPVLALSLSFDHRQIDGATGQNAMNHIKRLLNNPELLLMEG
>NC_017353.1|WP_002459424.1|1874809_1875787_-|alpha-ketoacid-dehydrogenase-subunit-beta
MAQMTMVQAINNALKTELQNDENVLIFGEDVGVNGGVFRVTEGLQKEFGEDRVFDTPLAESGIGGLALGLTTQGYRPVMEIQFLGFVFEVFDEVAGQIARTRFRSGGTKTAPVTIRTPFGGGVHTPELHADNLEGILAQSPGIKVVIPSGPYDAKGLLISSIRSNDPVVYLEHMKLYRSFREEVPEEEYTIEIGKAKVVKEGTDITLIAYGAMVQESVKAAEELEKDGHSVEVIDLRTVQPLDMDTLVASVEKTGRVVVVQEAQRQSGVGANVAAELQERAILSLEAPIARVAAADTVYPFTQAENVWLPNKNDIVEQAKATLEF
>NC_017353.1|WP_002459425.1|1875790_1876903_-|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha
MAPKLQAQFDAVKVLNETQSKFEMVQILDVDGNVVNEDLVPDLTDEQLVELMERMVWTRILDQRSISLNRQGRLGFYAPTAGQEASQLASQYALEKEDFILPGYRDVPQIIWHGLPLTEAFLFSRGHFKGNQFPEGVNAFSPQIIIGAQYIQTAGVAFGIKKRGKKAVAITYTGDGGSSQGDFYEGINFASAYKAPAIFVIQNNNYAISTPRSKQTAATTLAQKAISVGIPGIQVDGMDPLAVYQATKEARDRAVAGEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWEKKDPLVRFRKFLENKGLWNEDKENEVIERAKDDIKKAIKEADKVEKQKVTDLMDIMYEEMPQNLAEQYEIYKEKESK
>NC_017353.1|WP_002459426.1|1877069_1877699_-|YkyA-family-protein
MKLYRALGVLLASTLLLAGCTTDRKEVRAYEDTIQQASSNEQVINSTGQKLNDLEKQKQQYYKKIVTNNPDTRVKVADKMISNINERSKEFNKEVKAMNASNKEFKKASKHINQIKDDSKRKELKELDDALKDKYKKHDDYAAAYRNILDKERSYFKLLKQKTVMQQQEKEKGEAINKAQKTFKQKFEAYIKALNKVNKEKGDIDKISE
>NC_017353.1|WP_002478367.1|1877836_1878388_+|peptide-deformylase
MLTMKDIIKDGHPTLRAEAQDVDFPLSDEDKQTLKSMREFLINSQDDEIANRYGLRSGVGLAAPQIDISKKMIAVYLPDDGNGRSYDLMLVNPKVVSYSVQYAYLPTGEGCLSVDKNIPGLVHRHYRVTVKAKDIDGKDVKLRLKGYPAIVVQHEIDHLNGIMFYDHIDAEHPLTPLPDSIEV
>NC_017353.1|WP_002459428.1|1878822_1879041_+|DNA-dependent-RNA-polymerase-auxiliary-subunit-epsilon-family-protein
MAIFKVFYQHNKNEVIVRENTQTIYVEGETEEQVRRYLKDRNYNIEFITKLEGAHLEYEKEHSEHFNVENAE
>NC_017353.1|WP_002478368.1|1879040_1880720_+|ribonuclease-J
MKQLHQNEVGVYALGGLGEVGKNTYAVEYKDEIVIIDAGIKFPDDNLLGIDYVIPDYTYLEQNQDKIVGLFITHGHEDHIGGVPYLLKQINVPIYGGPLALGLIRNKLDEHNLLRNAELIEITEDSVIKSKHFEVSFYLTTHSIPEAYGVIVDTPEGKIVHTGDFKFDFTPVGAPANIAKMAQLGKEGVLCLLSDSTNALVPDFTLSEREVGQNVDKIFRNCKGRIIFATFASNIYRVQQAVEAAIKYNRKIVTFGRSMENNIKIGMELGYIKAPPETFVEPNKIHHIPKHELLILCTGSQGEPMAALSRIANGTHKQIKIIPEDTVVFSSSPIPGNTKSINRTINALYKAGAEVIHSKISNIHTSGHGSQGDQQLMLRLIQPKFFLPIHGEYRMLTAHGQTGVDCGVPEENVFIFDIGDVLALTHDSARKAGRIPSGNVLVDGSGIGDIGNVVIRDRKLLSEEGLVIVVVSIDFKTNKLLSGPDIISRGFVYMRESGQLIYDAQRRIKTDVISKLNSNKDIQWHQIKSSIIETLQPYLYEKTARKPMILPVIMKVNEE
>NC_017353.1|WP_002459431.1|1881314_1881974_-|TrkA-family-potassium-uptake-protein
MDKEYVVIGLGRFGGSIVRELNALDMDVMAIDHDEARVNEYSDIATHAVIADTTDEAVMKSLGIRNFDHVIVAIGENIQSSTLTTLILKELGVKKVTAKAQNDYHAKILNKIGADTVVHPERDMGRRIAHNVASASVLDYLELSDEHSLVELKASEKMAGQSIVNLDIRAQYGINIIAIKRGKEIIVSPDPNINIEIGDILIMIGHDNDLNRFEKKIVR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017353_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017353_10

1964069-1964163

Orphan

Consensus_repeat	Method
TTCCCCAGCTTGCACATTTCTGTTGAATTTCTTAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017353_10

>merge|NC_017353|10|1964069-1964163|CRISPRCasFinder
TTCCCCAGCTTGCACATTTCTGTTGAATTTCTTACAGAAATTCTTTGTGCTGGGGCCCCGTTCCCCAGCTTGCACATTTCTGTTGAATTTCTTAC

>NC_017353|10|9|1964069-1964163|CRISPRCasFinder
TTCCCCAGCTTGCACATTTCTGTTGAATTTCTTAC	AGAAATTCTTTGTGCTGGGGCCCCG
TTCCCCAGCTTGCACATTTCTGTTGAATTTCTTAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_017353.1\|WP_002478420.1\|1966337_1967309_-\|competence-protein-CoiA	unknown	unknown	gnl\|CDD\|226875
NC_017353.1\|WP_002459514.1\|1968361_1968757_-\|transcriptional-regulator-Spx	unknown	unknown	gnl\|CDD\|179316
NC_017353.1\|WP_002478423.1\|1971184_1972837_-\|peptide-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173869
NC_017353.1\|WP_002459519.1\|1972862_1973804_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224048
NC_017353.1\|WP_002478415.1\|1959956_1960766_-\|NAD-kinase	unknown	unknown	gnl\|CDD\|235317
NC_017353.1\|WP_002459509.1\|1963033_1963831_+\|DsbA-family-protein	unknown	unknown	gnl\|CDD\|372699
NC_017353.1\|WP_002478417.1\|1961973_1962546_+\|CYTH-domain-containing-protein	unknown	unknown	gnl\|CDD\|226601
NC_017353.1\|WP_002478422.1\|1970220_1970976_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NC_017353.1\|WP_002478416.1\|1960780_1961416_-\|GTP-pyrophosphokinase-family-protein	unknown	unknown	gnl\|CDD\|225232
NC_017353.1\|WP_002478414.1\|1959105_1959960_-\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NC_017353.1\|WP_002459515.1\|1969044_1970034_+\|tryptophan--tRNA-ligase	unknown	unknown	gnl\|CDD\|234866
NC_017353.1\|WP_002478419.1\|1964477_1966286_-\|oligoendopeptidase-F	unknown	unknown	gnl\|CDD\|341071
NC_017353.1\|WP_002478421.1\|1967409_1968141_-\|adaptor-protein-MecA	unknown	unknown	gnl\|CDD\|235030
NC_017353.1\|WP_002459500.1\|1954779_1955550_-\|enoyl-ACP-reductase-FabI	unknown	unknown	gnl\|CDD\|236308
NC_017353.1\|WP_002478425.1\|1974890_1975955_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NC_017353.1\|WP_002459501.1\|1955837_1957682_-\|monovalent-cation:proton-antiporter-family-protein	unknown	unknown	gnl\|CDD\|366411
NC_017353.1\|WP_002459499.1\|1953375_1954461_+\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NC_017353.1\|WP_002459506.1\|1961432_1961780_-\|hypothetical-protein	unknown	unknown	unknown
NC_017353.1\|WP_002478418.1\|1962645_1963011_+\|truncated-hemoglobin	unknown	unknown	gnl\|CDD\|225223
NC_017353.1\|WP_002478424.1\|1973793_1974876_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521

Protein	Function_ID	Function_description	E-value
NC_017353.1\|WP_002478420.1\|1966337_1967309_-\|competence-protein-CoiA	gnl\|CDD\|226875	COG4469, CoiA, Competence protein CoiA-like family, contains a predicted nuclease domain [General function prediction only].	3.7556e-47
NC_017353.1\|WP_002478423.1\|1971184_1972837_-\|peptide-ABC-transporter-substrate-binding-protein	gnl\|CDD\|173869	cd08504, PBP2_OppA, The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding component of an ATP-binding cassette (ABC)-type oligopeptide transport system comprised of 5 subunits. The transport system OppABCDEF contains two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NC_017353.1\|WP_002459519.1\|1972862_1973804_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	7.99352e-127
NC_017353.1\|WP_002478415.1\|1959956_1960766_-\|NAD-kinase	gnl\|CDD\|235317	PRK04885, ppnK, inorganic polyphosphate/ATP-NAD kinase; Provisional.	0
NC_017353.1\|WP_002459509.1\|1963033_1963831_+\|DsbA-family-protein	gnl\|CDD\|372699	pfam13743, Thioredoxin_5, Thioredoxin.	8.82108e-51
NC_017353.1\|WP_002478417.1\|1961973_1962546_+\|CYTH-domain-containing-protein	gnl\|CDD\|226601	COG4116, COG4116, Uncharacterized protein conserved in bacteria [Function unknown].	1.37257e-65
NC_017353.1\|WP_002478422.1\|1970220_1970976_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	4.29549e-25
NC_017353.1\|WP_002478416.1\|1960780_1961416_-\|GTP-pyrophosphokinase-family-protein	gnl\|CDD\|225232	COG2357, COG2357, PpGpp synthetase catalytic domain [General function prediction only].	2.13901e-97
NC_017353.1\|WP_002478414.1\|1959105_1959960_-\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	7.96151e-75
NC_017353.1\|WP_002459515.1\|1969044_1970034_+\|tryptophan--tRNA-ligase	gnl\|CDD\|234866	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed.	0
NC_017353.1\|WP_002478419.1\|1964477_1966286_-\|oligoendopeptidase-F	gnl\|CDD\|341071	cd09608, M3B_PepF, Peptidase family M3B, oligopeptidase F (PepF). Peptidase family M3B oligopeptidase F (PepF; Pz-peptidase B; EC 3.4.24.-) is mostly bacterial and includes oligoendopeptidase F from Lactococcus lactis. This enzyme hydrolyzes peptides containing between 7 and 17 amino acids with fairly broad specificity. The PepF gene is duplicated in L. lactis on the plasmid that bears it, while a shortened second copy is found in Bacillus subtilis. Most bacterial PepFs are cytoplasmic endopeptidases; however, the Bacillus amyloliquefaciens PepF oligopeptidase is a secreted protein and may facilitate the process of sporulation. Specifically, the yjbG gene encoding the homolog of the PepF1 and PepF2 oligoendopeptidases of Lactococcus lactis has been identified in Bacillus subtilis as an inhibitor of sporulation initiation when over-expressed from a multicopy plasmid. This PepF family includes Streptococcus agalactiae PepB, a group B streptococcal oligopeptidase which has been shown to degrade a variety of bioactive peptides as well as the synthetic collagen-like substrate N-(3-[2-furyl]acryloyl)-Leu-Gly- Pro-Ala in vitro.	0
NC_017353.1\|WP_002478421.1\|1967409_1968141_-\|adaptor-protein-MecA	gnl\|CDD\|235030	PRK02315, PRK02315, adaptor protein MecA.	5.63227e-89
NC_017353.1\|WP_002459500.1\|1954779_1955550_-\|enoyl-ACP-reductase-FabI	gnl\|CDD\|236308	PRK08594, PRK08594, enoyl-[acyl-carrier-protein] reductase FabI.	1.06235e-176
NC_017353.1\|WP_002478425.1\|1974890_1975955_-\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	4.4776e-96
NC_017353.1\|WP_002459501.1\|1955837_1957682_-\|monovalent-cation:proton-antiporter-family-protein	gnl\|CDD\|366411	pfam00999, Na_H_Exchanger, Sodium/hydrogen exchanger family. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.	1.07213e-60
NC_017353.1\|WP_002459499.1\|1953375_1954461_+\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	7.35842e-56
NC_017353.1\|WP_002459514.1\|1968361_1968757_-\|transcriptional-regulator-Spx	gnl\|CDD\|179316	PRK01655, spxA, transcriptional regulator Spx; Reviewed.	1.88335e-88
NC_017353.1\|WP_002478418.1\|1962645_1963011_+\|truncated-hemoglobin	gnl\|CDD\|225223	COG2346, COG2346, Truncated hemoglobins [General function prediction only].	5.3197e-44
NC_017353.1\|WP_002478424.1\|1973793_1974876_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	0

>NC_017353.1|WP_002459509.1|1963033_1963831_+|DsbA-family-protein
MAEELKLMHNESREDANLSPVSKIEIYSFFDPFDSDCFKLSALISKLRIEYNQYIRIRHILNPSLRVLTKCQAQSTSEFDNIALAYKAAELQGRLRAERFIHLMQNEIVPKCDIITEDMICNCIKNAGLDYEVFKEDLQTSKLTESLKVDLHIAREMEIEQSPSLVFFNENIHEEGLKVEGLYPYHIYTYIINELMGTPIEKQLPPKLEIYIQKKQLVTMEELLTIYEWPEKLLNKELKKLVLQQKIEKLYYPEGHFWKSKMPKL
>NC_017353.1|WP_002478418.1|1962645_1963011_+|truncated-hemoglobin
MTSTPYDIIGQEALYKMIDHFYALVEQDDRINHLFPGDFQETSRKQKQFLTQFLGGPNLYTAEHGHPMLKKRHLRFKITTYERDAWLENMYIAIQAAQFPAGVGEYLYERLRLTANHMVNA
>NC_017353.1|WP_002478417.1|1961973_1962546_+|CYTH-domain-containing-protein
MSTNHEIEFKQLLTASQYDDIRQKYFQNVMPFSQTNFYIDTSDFKLKANHSALRIRVKDDSYELTLKVPATVGLTEYNHSTNLIPEIGKTLTLQQFPEDIQHQLMQFDITDDELNILGSLTTHRMEVYFKHQLLVLDHSEYLGTEDYELEFEVNDYEQGKQIFLNFLQECGIDYVKPKNKVQRFFDYKAQ
>NC_017353.1|WP_002459506.1|1961432_1961780_-|hypothetical-protein
MRIYVNEIKVKDDGIYCYSDDPTDGLEEVGQMLVDSDNYGFAYILDDGQSYSYLIFVEETWSMLHENRDKTIIVNDDLKLEHFQEEFDFILDNIVGNNNYGKEFVAAVEKTFELE
>NC_017353.1|WP_002478416.1|1960780_1961416_-|GTP-pyrophosphokinase-family-protein
MNQWDQFLTPYKQAVDELKVKLKGLRKQYEVGEHASPIEFVTGRVKPITSIIDKANKRGIPFDRLQQEMYDIAGLRMMCQFVDDIDVVVKMLRQRQDFRVIEERDYINNTKQSGYRSYHVIIEYPIETLDGQKKILAEIQIRTLAMNFWATIEHTLRYKYDGDYPDEIQHRLERAAEAAYLLDEEMSEIKEEIQEAQKYYSQKRAKKHDNN
>NC_017353.1|WP_002478415.1|1959956_1960766_-|NAD-kinase
MRYTILSKGDSKSNALKHKMISHMKDFHMTQNDENPEIVISVGGDGTLLQAFHQYSHMLSQVAFVGVHTGHLGFYADWLPHEVEKLIIEINNSEFQVIEYPLLEMIVRYNDNGYETRYLALNEATMKTDNGSTLVVDVNIRGKHFERFRGDGLCISTPSGSTAYNKALGGALIHPSLEAIQIAEIASINNRVFRTVGSPLVLPKHHTCYITPVNHDTIRTTIDHVSIKHKNVSGIQYRVANEKVRFARFRPFPFWKRVHDSFIESDDER
>NC_017353.1|WP_002478414.1|1959105_1959960_-|RluA-family-pseudouridine-synthase
MRFTYAIKSPDVLKSFLQQQGFSKKTTSAIKQNGALLVNHEPVTVRYQLQPGDKLTIILPTEIPSANLQAFHHPLDIVYEDDYLLIVCKPSLQNCAPSREHPHESLIEQVLAYCHENDNDFTPHIVTRLDRNTTGLVLLAKHGHIHHLLSHIKINKRYIALCHGATQPEGIIEAPIARANDSIITRQVSSTGKYAKSTYRTLNSKQNVSLCEVTLHTGRTHQIRVHFQYIGHPLIGDALYGGNHDMIHNHCLQCTALQFKHPILHKTISITIDYKQLICLYNML
>NC_017353.1|WP_002459501.1|1955837_1957682_-|monovalent-cation:proton-antiporter-family-protein
MEFFSLVIVVVAAFFTPILVNRLNISFLPVVVAEILMGVIIGNSFLNLVEKDSMLNILSTLGFIFLMFLSGLEIDFSAFKKDTRNRQGQSQEDKNVPSHLNMALTVFIFIMIISIVLAYAFKWLGLVDDVLLMIIIISTISLGVVVPTLKEMNIMRTTIGQFILLVAVLADLFTMVLLTVYGALNGQGGGSIWLSAILVVFTAIFYIIGILFKHMSFLQKLMSGTTQIGIRAIFALIILLVALAEGVGAEYILGAFLAGVVVSLLKPDEELVQKLDSFGYGFFIPIFFIMVGVDLDIPSLIKEPALLIIIPVLIGAFLISKLLPVLFIRRWFDTKTTIASAFLLTSTLSLVIAAAKIAEQLKTISSETSGILILSAVITCVFVPVVFKKLFPIPDEVNRRIEVALIGKNQLTIPIAQNLTSQLYNVSLYFRKDLSDHRHLADSITVLEINDYDEAILTRLGLFDNDIVVCATNDDDINRRVAMMAEEHGVNRVICRLETMTDDVGMKNSGIEIFSNFLSNKIFLKGLIETPNMLNLLSNVETSLYEIEMLNHKYENLELRNFPFGGDVIFVRIIRNNESIVPHGDTQLRYKDRLIVTGSKEYVDELKGELEFYY
>NC_017353.1|WP_002459500.1|1954779_1955550_-|enoyl-ACP-reductase-FabI
MLNLENKTFVIMGIANKRSIGFGVAKVLDKLGAKLVFTYRKERSRKELEKLLEQLNQNDPKLYQIDVQKDEDVINGFAKIGEEVGNIDGVYHSIAFANIEDLRGRFSETSREGFLLAQDISSYSLTLVAHEAKKIMPHGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGQDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLRRNVDQEEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK
>NC_017353.1|WP_002459499.1|1953375_1954461_+|AI-2E-family-transporter
MLNKVWFRTGVALLILFLLIKLIMEVHSVFTPIATIIGSVFLPFILSGFLFYICLPFQTLLEKFGFPRWASITTIFIALIAIVAVVVAFIAPIIISNVNSLIHAIPTIQNDVERIINFSLKQMDKLPSDVTTRINNTVKSLGDGVSDVLANSLSYITSFISTIFLLVMVPFFLIYMLKDHEKFIPAVAKFFKGERKVFAVGLLQDLNFTLKSYIQGQVTVSVILGIILYIGYTIIGLPYTPLLVLFAGVANLIPFLGPWLSFAPAGILGIIDSPTTFIWVCIVTLIAQQLEGNVITPNVMGKSLSIHPLTIIVVILAAGDLGGFTLILIAVPLYAVLKTVASNIFKYRTRIMDKANSDVKD
>NC_017353.1|WP_002478419.1|1964477_1966286_-|oligoendopeptidase-F
MSQQLTREEQEQQYPQYTWDLTTIFESDEAFEQAFKSVENKIGEEQRYQGHLGDNAQTLYEALAFEDELGSQLEKVYVYAHLKQDQDTANDKYTGFESRAHQLIIKFSSAWSFLIPEILQIDEVKLQTFIDENDNLKRYAFDLKLINEKREHILDADTEKLLTEAQDALSTPSNVYGMFSNADLEFEDAIDKDGNTHPLTQGTFIKYLESDDRKLRESAYKNVYKAYGSHNNMLGATLAGEVKKNVFNARTHHYKSARQRALSNNHIPEEVYDNLVDTVHKYLPLLHRYTKLRQELLGLDDLKMYDLYTPLVKDIKFEMPYEEAKSWMLKALEPMGEEYLNVVKEGLENRWVDVYENKGKRSGGYSSGAHLTNPFILLNWSDTISDLYTLIHEFGHSAHSYFSRQNQPSNASDYSIFVAEVASTCNEALLSDYMDKHLDDERRLLLLNQELERFRATLFRQTMFAEFEHKIHQIEEAGEPLTPTRMNEEYAALNKQYFGETVETDEDISKEWSRIPHFYMNYYVYQYATGYSAAQSLSHQILTEGKPAVERYINEFLKKGSSNYPIEILKNAGVDMTSPKPIEQACEVFEQKLDAFEKLIKA
>NC_017353.1|WP_002478420.1|1966337_1967309_-|competence-protein-CoiA
MLSAFNNKRQLIKAVDAMNSEHYYCPSCRELVILKRGYKVKAHFAHRSHSLCIHAKGESQLHYQMKYHIAQSYLLHGQKVEIEPFLTDIQQYPDLLINDKFVIELQLSTIPFNIIKQRTKGLMSVGKHVIWLLQGLQFSRNQLTLTQFQSSFIHPEQRTLYEWDDREKSFYCYHHIQHLGGKRFSARKTQTSPLNILKLQSPCPSVSFKLANHHIKYYIQQCRRQNSVLEPTLSAIYQLRLSDDQATQFLGYIFPNQIYINSHPIAWQAQLLLYLAHKINFNSFKSSVKFRNLLFSNATEEDILNMLITQYKQTFDSMFKRAK
>NC_017353.1|WP_002478421.1|1967409_1968141_-|adaptor-protein-MecA
MRIERVDETTVKLFITYSDIEARGFSREDLWTNRKRGEEFFWSMMDEINQEEEFVVEGPLWIQVHAFEKGVEVLISKSKNDEAMDEAMNMSDDDANDQFDQQLNELLAASVLDKDQKADDMFEQRANNKSTNKSDTVQSQRANMRTIIVKFDDLEHVIDYAYHHNQATDSYEDLLYMLDSNYYYAVHFDEKVEQEDINDFYSQLLEYAYPTDKTEVYLDDYGKIIMSYNVTAQVRRYFPDTAE
>NC_017353.1|WP_002459514.1|1968361_1968757_-|transcriptional-regulator-Spx
MVTLFTSPSCTSCRKAKAWLQEHDIPYTERNIFSEHLTIDEIKQILKMTEDGTDEIISTRSKTYQKLNVDIDSLPLQDLYSIIQDNPGLLRRPIILDDKRLQVGYNEDEIRRFLPRKVRTFQLKEAQRLVD
>NC_017353.1|WP_002459515.1|1969044_1970034_+|tryptophan--tRNA-ligase
METLFSGIQPSGIPTLGNYIGALKQFVEVQDDYDCFFCIVDQHAITVPQDRLKLRKQIKQLAAIYLASGIDPDKSTLFIQSEVPAHVQAGWMLTTIASVGELERMTQYKDKAQKRTDGIPAGLLTYPPLMAADIVLYNTNIVPVGEDQKQHMELTRNLVERFNSRYNDVLTKPEIRMPKIGGRVMSLQEPTKKMSKSDDNQKNFISLLDEPHIAAKKIKSAVTDSDGIIKFDRDNKPGISNLLSIYSSLTDESIQDIEQKYEGEGYGKLKSDLAEIVKDFLTTFQEKYNAFYQSEELDIILDKGRDKAHKASMKTLKKMEKAMGLGRKR
>NC_017353.1|WP_002478422.1|1970220_1970976_+|class-I-SAM-dependent-methyltransferase
MSKEPGHTFLAKLGKTRLRPGGKKATDWLITQGQFSYKKQVLEVACNMCTTSIYLAKTYQCHITAVDLNKKALDKGRLNVKKAHLEHLIQLQQANAIRLPFEDNQFDIILNEAMLTMLPMKAKQQAVAEYFRVLKPGGILLTQDVAVMNDDKEKEVIQHLSSAINVNVTPLTPEHWTQLYKEAGFSSVHNHYEPMTLMTPKGMIYDEGIFGTIKIIKNALKKDNRSMFKRMFITFKNHKSDLNYIVHAATK
>NC_017353.1|WP_002478423.1|1971184_1972837_-|peptide-ABC-transporter-substrate-binding-protein
MKKLMSILAFFLVTSTALTGCGNKESLYSDKGNVFRKVLTQDMSSLDTGLITEEISFEVTAQAFEGLYVLGRGDKAELGVAQDFPKKSNGGKTLTVKLKKDAKWSNGDPVTAQDFVYAWRKVVNPKTGSEFAYIMNDIKNASQINTGKKPVKDLGIKALDSHTLKIDLEKPIPYINQLLALNTFDPQNEKIAKKYGESYGTKANKAVYNGPFKVDQWKPEDKIMLSKNDKYWDRDKVKLDKVNYKVLKDQQAGASLYDTGSIDDTTITADQVNKYKKSSGLKYRLTSGTFFIKMNEKEFPAFKNKNLRLAIAQSINKQGFVDSVKNNGSTPANTFTAKGVAKSPNNKDFASTIDSELKYNPKSAKSHWDKAKNELGKNQIAFSMNTEDTPDAKIAAEYIKSQVEKNLPGVTLKIKQLPFKQRVNLELTENFQASLGGWSADYPDPTAYLEIMTTGNAQNNTDWGNKKYDSLIKSAKGDLLQKTNERYQAMKQAEELLLDDAPVAPIYQKGEAHLMNPQVKNFYFHKVGPNYSLKQVYIDKSIDRETGKKK
>NC_017353.1|WP_002459519.1|1972862_1973804_-|ABC-transporter-ATP-binding-protein
MKNKDILLEVKHLKQYFNEGKRNEVRAIEDISFNIYKGETLGLVGESGCGKSTTGKAIIKLNEITSGEIMYDGVDIQKIKNRKDSLRFNKKIQMIFQDPYASLNPRLKVMDIVAEGIDIHKMAVNKRDRKKRVYDLLETVGLSKEHANRYPHEFSGGQRQRIGIARALAVEPEFIIADEPISALDVSIQAQVVNLMLKLQQERGITFLFIAHDLSMVKYISDRIAVMYFGKIVELGPSEEIYHHPLHDYTKSLLSAVPQPDPESERTRERVAYIADDNLDNDRTLMEIRPEHYVFVTNEEAEQLKTQSMVSHT
>NC_017353.1|WP_002478424.1|1973793_1974876_-|ABC-transporter-ATP-binding-protein
MSERVLEVNDLHVSFDINAGEVQAVRGVDFYLNKGETLAIVGESGSGKSVTTKAITKLFQGDAGRIKQGEIIFLGEDLAQKSENELIKLRGKDISMIFQDPMTSLNPTMQIGKQVMEPLIKHKHFSKSQAKKRALEILNLVGLPNAEKRFKAYPHQFSGGQRQRIVIATALACEPKVLIADEPTTALDVTMQAQILDLMKKLQQKINTSIIFITHDLGVVANIADRVAVMYGGQMIETGDVDEIFYDPKHPYTWGLLSSMPDLDTKNDTPLVAIPGTPPDLLNPPQGDAFARRSQYALDVDFKAEPPWFKISPTHFVKSWLLDERAPKVEPPEMVQKRAHNMPNNYDKPLKVERVSFNEK
>NC_017353.1|WP_002478425.1|1974890_1975955_-|ABC-transporter-permease
MTQNIDKSLDDQSNAAMTHTSEGIMATDFVMRDIDLNKEPEMQRESKNFWQDAWAQLKRNKLAIVGMIGLILIVILAFIGPMLSHHDYAEQDVNRRNLPAKIPVLDKVSFLPFDGTGSDGSNAYDKAKVNENFWFGTDQLGRDLWTRTWKGAQISLFIGIVAAILDIFIGVVYGAISGFFGGRVDNVMQRILEIVASIPNLIVVILFVLIFEPSIWTIILAMSITGWLGMSRVVRGEFLKLKNLEFVMASRTLGASKFNLIFKHILPNTLGAIVVTSMFTVPSAIFFEAFLSFIGIGVPAPQTSLGSLVNDGRAMLLIHPHELFIPATVLSLLILFFYLFSDGLRDAFDPKMRK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017353_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017353_11

2201778-2201857

Orphan

Consensus_repeat	Method
CCAAGCAAAGCAAGTTGGGGTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017353_11

>merge|NC_017353|11|2201778-2201857|CRISPRCasFinder
CCAAGCAAAGCAAGTTGGGGTGGGGCCCCAACAAAGAGAAATGCGAAAAGCATTTCGCCAAGCAAAGCAAGTTGGGGTGG

>NC_017353|11|10|2201778-2201857|CRISPRCasFinder
CCAAGCAAAGCAAGTTGGGGTGG	GGCCCCAACAAAGAGAAATGCGAAAAGCATTTCG
CCAAGCAAAGCAAGTTGGGGTGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017353.1\|WP_002479360.1\|2205752_2207267_-\|ABC-transporter-permease/substrate-binding-protein	unknown	unknown	gnl\|CDD\|270328
NC_017353.1\|WP_002459754.1\|2207263_2208232_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
NC_017353.1\|WP_002479357.1\|2200723_2201638_+\|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl\|CDD\|224513
NC_017353.1\|WP_002479361.1\|2210242_2212126_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NC_017353.1\|WP_002459755.1\|2208447_2210229_-\|DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|273594
NC_017353.1\|WP_002479362.1\|2212237_2213053_+\|ZIP-family-metal-transporter	unknown	unknown	gnl\|CDD\|223505
NC_017353.1\|WP_002459740.1\|2191329_2192307_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226965
NC_017353.1\|WP_002479363.1\|2213220_2215158_-\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	unknown	unknown	gnl\|CDD\|224287
NC_017353.1\|WP_037553882.1\|2198890_2200396_+\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NC_017353.1\|WP_014533353.1\|2197223_2198093_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NC_017353.1\|WP_002459751.1\|2202779_2203835_-\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|235106
NC_017353.1\|WP_002459738.1\|2189610_2190393_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226963
NC_017353.1\|WP_002479364.1\|2215708_2216713_-\|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224895
NC_017353.1\|WP_002459743.1\|2195951_2196350_-\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|179603
NC_017353.1\|WP_002459741.1\|2192675_2193644_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NC_017353.1\|WP_002479355.1\|2198105_2198606_+\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl\|CDD\|237320
NC_017353.1\|WP_002459752.1\|2203957_2205472_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NC_017353.1\|WP_002479353.1\|2190389_2191349_-\|iron-chelate-uptake-ABC-transporter-family-permease-subunit	unknown	unknown	gnl\|CDD\|226964
NC_017353.1\|WP_002479359.1\|2202011_2202542_-\|5'-3'-deoxyribonucleotidase	unknown	unknown	gnl\|CDD\|226895
NC_017353.1\|WP_002459742.1\|2193883_2195989_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|236069

Protein	Function_ID	Function_description	E-value
NC_017353.1\|WP_002479360.1\|2205752_2207267_-\|ABC-transporter-permease/substrate-binding-protein	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.02691e-145
NC_017353.1\|WP_002459754.1\|2207263_2208232_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	1.83411e-153
NC_017353.1\|WP_002479357.1\|2200723_2201638_+\|diacylglycerol-kinase-family-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	1.26772e-70
NC_017353.1\|WP_002479361.1\|2210242_2212126_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NC_017353.1\|WP_002459755.1\|2208447_2210229_-\|DNA-helicase-RecQ	gnl\|CDD\|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_017353.1\|WP_002479362.1\|2212237_2213053_+\|ZIP-family-metal-transporter	gnl\|CDD\|223505	COG0428, COG0428, Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism].	5.72871e-55
NC_017353.1\|WP_002459740.1\|2191329_2192307_-\|ABC-transporter-permease	gnl\|CDD\|226965	COG4606, CeuB, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	6.54329e-143
NC_017353.1\|WP_002479363.1\|2213220_2215158_-\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
NC_017353.1\|WP_037553882.1\|2198890_2200396_+\|peptide-MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	9.88727e-161
NC_017353.1\|WP_014533353.1\|2197223_2198093_+\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	5.52796e-12
NC_017353.1\|WP_002459751.1\|2202779_2203835_-\|histidinol-phosphate-transaminase	gnl\|CDD\|235106	PRK03158, PRK03158, histidinol-phosphate aminotransferase; Provisional.	0
NC_017353.1\|WP_002459738.1\|2189610_2190393_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226963	COG4604, CeuD, ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism].	1.14786e-131
NC_017353.1\|WP_002479364.1\|2215708_2216713_-\|biotin-dependent-carboxyltransferase-family-protein	gnl\|CDD\|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	2.06287e-131
NC_017353.1\|WP_002459743.1\|2195951_2196350_-\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|179603	PRK03600, nrdI, class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI.	3.30486e-55
NC_017353.1\|WP_002459741.1\|2192675_2193644_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	2.82769e-168
NC_017353.1\|WP_002479355.1\|2198105_2198606_+\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl\|CDD\|237320	PRK13258, PRK13258, 7-cyano-7-deazaguanine reductase; Provisional.	2.68514e-76
NC_017353.1\|WP_002459752.1\|2203957_2205472_-\|peptide-MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	1.84386e-152
NC_017353.1\|WP_002479353.1\|2190389_2191349_-\|iron-chelate-uptake-ABC-transporter-family-permease-subunit	gnl\|CDD\|226964	COG4605, CeuC, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	2.34297e-106
NC_017353.1\|WP_002479359.1\|2202011_2202542_-\|5'-3'-deoxyribonucleotidase	gnl\|CDD\|226895	COG4502, COG4502, 5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism].	1.3534e-84
NC_017353.1\|WP_002459742.1\|2193883_2195989_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0

>NC_017353.1|WP_002479357.1|2200723_2201638_+|diacylglycerol-kinase-family-lipid-kinase
MTDKYNHGVLFYHEHSGLKDIYNGLGEVTKALSSICKQLSIQVSENEGDIIKYCQKIKQGDYGQKIDILFILGGDGTVNEMVNGVMKHQLDLPIGIIPGGTFNDFTKTLNIHPNFKQASEQLKYAQIGQYDVIQVNKEFALNFVGLGLIVQNAENVQNGAKDIFGKLSYIGSTVKTLMDPSNFDFTLTIDGEKTTGNTSMLLIANGPNIGGSRIPLTDLSPQDGKLNTFIFDEQSFSILNDIFKKRDSMNWNEITQGIDHISGKDIRIDTKPIMKVDIDGEIRLEAPLDIKVLPKALKLLTIPT
>NC_017353.1|WP_037553882.1|2198890_2200396_+|peptide-MFS-transporter
MASHNSHELAVEKIPQKGFFGHPKGLGVLFFVEFWERFSYYGMRAMLIFYMYYAINQGGLGIDKATAMSIMSVYGALIYMSSIPGAWIADRITGTRGATLIGAVLIIIGHVCLSLPFQMFGLFASMFFIIVGSGLMKPNISNIVGRLYPENDVRIDAGFVIFYMSVNLGALISPIILQNFLDVNNFHGGFLIAAIGMALGLVWYILFNRKTLGQVGMQPTNPLTAEEKKKYTFIIVAIVAVITAVLIVTYLTNTLSFNLVSNTVLVLGIVLPIIYFATMIYSKDVDDTERSRVKAFIPLFILGMIFWSIQEQGSNVLNIYGLEKSDMHLNIFGWTTRFGEAWFQSINPLFILLFAPLISLMWMKMGKKQPSLPVKFALGTFLAGLSYLIMGLIGVSYGSTTFSVNWVILSYVICVVGELCLSPTGNSAAVKLAPKSFNAQMMSVWLLTNASAQAINGTVVKYIDDLGQTTYFILLGSIAVVVTLIVLAFTPIIKKAMKGIH
>NC_017353.1|WP_002479355.1|2198105_2198606_+|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MTQGRQEEEMKDITLLGNQNNNYQFDYRPDVLETFVNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPDTKYARMAEHRLMNHDMYPEKIDNR
>NC_017353.1|WP_014533353.1|2197223_2198093_+|DMT-family-transporter
MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNFVAMFIPLFFIYKYKQPMFGKLRNQPLLIGRSTLGLIGVLLNIFAIDHMVLSDADTLMKLNPFWTILLSLLFLHEKVRKYQISAMIIAIMGMLLIVKPEFSSAILPSLAGLFSGIFAASAYTCVRALSRREQPYTIVFYFSLFSVIVLIPFSIATFEPMTTTQILYLLGAGLAAAVGQIGITLAYSFAAAKDISIFTYASIIFTALFGFILFGETPDMYAIVGYIIIISASYYMFDQARRESNTQQSH
>NC_017353.1|WP_002459743.1|2195951_2196350_-|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MKVIYFSFSGNVQRFIKRTELSDVMEITEDNCQEEVNEPYILVTGTIGFGEVPQEVQQFLQVNHQHLQAVAASGNRNWGQNFAKAGQTISEQYNVPLLMKFEVQGSNSDVKEFKDKVGQFNENYEREKIQSY
>NC_017353.1|WP_002459742.1|2193883_2195989_-|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MKIMNEKKYNHIELNNEVTKRKESGFFNLEKDQEALKVYLEEIHDKTIYFDDEIERLHYLVDHDFYFNVFDKYSEIDLREITDFAKSIEFNFASYMSASKFYKDYALKTNDKSQYLEDYNQHVTIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPVAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKQEYGVTLDDIDLEQYYDDMVANPNIIKKKKDAREMLNTIAQTQLQSGYPYLMFKDNANKVHANSNIGQIKMSNLCTEIFQLQETSIINDYGIDDEIKRDISCNLGSLNIVNVMETGKFRDSVFTGMDALTVVSDEANIQNAPGVRKANSELHSVGLGVMNLHGYFAKNKIGYESEEAKDFANVFFMMMNYYSLERSMQIAKERGQVYQDFEQSDYANGKYFSFYTAQDITPRFAKVQQLFEGIEIPTAEDWKALQQQVEAHGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPETMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELSRLYVYAHYKGLKSLYYTRNKLLSVEECTSCAI
>NC_017353.1|WP_002459741.1|2192675_2193644_-|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MKAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLTDDERNTFKRALAGLTGLDTHQADDGMPLIMLHTTDLRKKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDTWVIEEPHLKYKADKIIENYHKLWGKEASIYDQYIARVSSVFLETFLFYSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGIDAQSLRNELSENEKQQADKEMYVLLEDLYSNEVSYTHMLYDDIGLTEDVLNYVKYNGNKALSNLGFDPYFEEKDFNPIIENALDTTTKNHDFFSVKGDGYTLALNVEALRDEDFIFEN
>NC_017353.1|WP_002459740.1|2191329_2192307_-|ABC-transporter-permease
MKLLLKGYTLLICLVIMSIISLFVGVSQLSITDIFHLTKEQLNILLSSRIPRTVSILISGSTLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILISLVCFPQGHILLKLAFAVLCSLFGTFLFVKLIEMIRVKEVIFVPLLGIMLGGIVSSFTTFIALRTNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLIITYIFANHFTIAGMGKDFSHNLGVNYEQIVRIALFITASITALVVVTVGTLPFLGLIVPNIISIYRGDHLKNALPHTMMLGACFVLFSDIIGRLIVYPFEINIGLTIGVFGTVIFLVLLMKGRKNYANDFE
>NC_017353.1|WP_002479353.1|2190389_2191349_-|iron-chelate-uptake-ABC-transporter-family-permease-subunit
MQMTLNKKLCALIGVTVIAALFYLFVGLDYEIFDYQFQSRFRKFILIILVGGAIGTSVVVFQAITRNRLLTPSIMGLDSVYLFAKVIPIFLLGAQSQFVTNIYLNFALTLVGMVLFALILFQFMFKVGNFSVYFILLVGVILGTFFRSITSFIQLIMDPDSFLAVQSAMFANFDASNSNLVIGSAILLCTLVIVIIVILPYLDVLLLGRAQAMNLGVNYSRVTRLLLILVALLVSISTALVGPITFLGLLTVNLAHEFMKTFQHKYILPATILMGWISLFIAQWIVENLFEATTEVSLIIDLIGGSYFIYLLIKRRNTN
>NC_017353.1|WP_002459738.1|2189610_2190393_-|ATP-binding-cassette-domain-containing-protein
MIRIKNMTQSIQGKAILKDISVDIQKGRLTSLIGPNGAGKSTLLSAISRIIEHDSGAIELEDIDIAAYRKNLLAQKLSILKQTNHTDMNITVEQLVNFGRFPYSKGRMKEADYEQVDYAINLLHLEDIRQRDLKTLSGGQRQRAYIAMTIAQNTDYILLDEPLNNLDMKHSVQIMQTLRRLCRELNKTIVIVLHDINFASCYSDDIIALKDGELVKADEKDAVIQKEVLQELYDMNVAIESIKGQRICLYFDEQLVEDVT
>NC_017353.1|WP_002479359.1|2202011_2202542_-|5'-3'-deoxyribonucleotidase
MTRQKIAIDMDEVLADTLGAIIEAVNKQTNLGITMEGLNGKKLKHMIPEHDGLVREILNAPGFFRQLPVLPAAQEVVEKLAAQYDVYIATAAMDVPTSFHDKYEWLLQHFPFLDPQHFVFCGRKNIVKTDYLIDDNPRQLAIFEGEPIIYTAAHNVNETRFTRVNGWKEVEAYFLN
>NC_017353.1|WP_002459751.1|2202779_2203835_-|histidinol-phosphate-transaminase
MKKQLDQLSAYQPGLSPRALKQQFGIEGELYKLASNENLYGPSPKVKQAITDHLDELYYYPETGSPSLRKAISAHLHIDESRILFGAGLDEVILMISRAVLTPGDKIVTSEATFGQYYHNAIVESADVVQVPLKNGGFDLEGILNEVDEQTALVWLCNPNNPTGTYFTHEKLHDFLSRVPSHVPVLIDEAYFEFVTAEDYPDTLKLQEEFDNAFLLRTFSKAYGLAGLRVGYVIATNEAIDKWNIIRPPFNVTRISEYAAIAALEDQDYLHDITQKNAQERQKFYAIPQSKHFLPSQTNFIFVVTDKVQELYQQLLQVGCITRPFPTGVRITIGFPEQNDKMIEVLQQFDY
>NC_017353.1|WP_002459752.1|2203957_2205472_-|peptide-MFS-transporter
MNNKNYTRQEIVSSVPQKGFFGHPKGLSTLFFTEFWERFSYYGMKAILAYYLYYAVTDGGFGLSQATGLQIVSIYGALIYMSGSIGGWIADRIIGTRHALFYGGILIMFGHILLAIPGNFTLVLIALLLLITGTGLLKPNISTTVGDLYSHDDVRLDGAFTIFYMGINLGSLLAPFITGYLQTRLGFHVGFAAAAVGMFLGLVVYVVTNKRFLGLAGLSVPNPLKKEEIKRLSLMVGSAIIMFAIILIVLQFTGLLSLESFTLIVTIIGIVLPIYIFIYMITNKKTNEVERKRIYSYIPLFITSVAFWMIQEQGSTVLANFADQNTQLSMSKLTNGLIDFQIPAAWAQSLNPIFIVVLAPVFANLWTRLGKHNPSTVHKFALGAIFAGLSYLVMMIPLMSSTELTHPLWLALSFLFITVGELCISPVGLSVTSKLAPKHLSAQMMALWMLSNATAQSINSQTVVFFKRISEQQFFMYSGLFTLIIGVLLFLISPIVIRAMRGVH
>NC_017353.1|WP_002479360.1|2205752_2207267_-|ABC-transporter-permease/substrate-binding-protein
MNEFITTLNARKEELLATLIEHIQISFIALLIAILIAVPLGIVLTKAKRISEIVMNIAAVLQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGIRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNPSLILIGAIPAALLAIIFDVILRLMAKLSYKKLMLATGAILLVIIIAIVAPLLSHKGDTITLAGKLGSEPSIITNMYKILIEEETDDTVEVKDGMGKTAFLFNALKSDDIDGYLEFTGTVLGELTKEDLKSKKEAAVYQQAKDSLQSKYDMTMLKPMKYNNTYALAVKRDFAQKHHLKTIDDLAKVTDQLKPGFTLEFNDRPDGFKAVKKAYNLNINNVKTMEPKLRYSAIEKGDINLIDAYSTDAELKQYDMVVLKDNKHVFPPYQGAPMFKEKFLNEHKEIKAPLNRLAGKISDEEMQEMNYKVTVKNEDPYQVAKAFLKKEGLIK
>NC_017353.1|WP_002459754.1|2207263_2208232_-|ABC-transporter-ATP-binding-protein
MIEFKNVTKRYGQNIAVHDLSFKINEGEFFVLIGPSGCGKTTTLKMINRLIPLTEGYIYFKDKPVSDFPVYEMRWDIGYVLQQIALFPHMTIKENIAQVPQMKKWKEKEIDQRVDELLEMVGLEPDKYKNRKPDELSGGQRQRVGVVRALAADPPVILMDEPFSALDPISREKLQDDLLALQTKINKTIVFVTHDIQEAMKLGDRICVMNQGHIEQIDTPLGFKTHPQSKFVQEFMGNYLQQTSVSQHIKLKELDITTPLNEMAASTDYPVVSADQYIDDLFDMLSKHEALLVENHDTHVQSLLTREDVFEYLAQGQRGETA
>NC_017353.1|WP_002459755.1|2208447_2210229_-|DNA-helicase-RecQ
MEAILSHYFGYQSFRPGQKEIITKILAHHNVLGVLPTGGGKSICYQIPGLKLGGTTVVISPLISLMKDQVDQLKAMGIHAAYLNSSLSQKQQKQIEQELASGKIQFLYVAPERFENQYFLSILRKLEIHLIAFDEAHCISKWGHDFRPSYQNVIQKVMTLPQDFVVIALTATATTEVQRDIMDKLYISADNRVKTSTKRRNLIFKVNPTYQRQKFVLDYVQAHRDEAGIIYCSTRKQVEELQEAIQSIDLEAAIYHAGLSNKEREQAQNDFVYDRIKVVVATNAFGMGIDKSNVRYVIHYNMPGDLESYYQEAGRAGRDGLKSECILLYSERDKGLHEYFISVSQADDDYKDKMGEKLTKMLQYTKTKKCLEATIVHYFEPNEKLEECQQCSNCVQENKTYDMTKEAKMIVSCVARMRQQENYSVIIQVLRGEQSDYIKYNHYDQLSTYGIMKAYTTSELSHLIDELRFKGFLNEHNEILICDQSVQSLLKEDVTIFTTPFRQKSKEKVYINTVEGVDRALYNELVDVRKQLSNKLGIAPVSIFSDYTLEEFAKRKPASKQEMIAIEGVGSYKLKHYCPNFLERIQSYKANIS
>NC_017353.1|WP_002479361.1|2210242_2212126_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MEAYKIEHLNKSYADKVIFDDLSLAISNHEKIGLVGINGTGKSTLLKVMGGIDDDFTGDITHPNQYRIRYSSQKQDLDGNLSVFEAVLSSETSTLQIIKHYEQAVQQYTVEQTDRNFQAMMAAQEAMDRHEAWDYNAEIKTILSKLGIHDTTKQVSSLSGGQQKRVVLAKTLIEQPDLLLLDEPTNHLDFESINWLINYVKQYPYTVLFVTHDRYFLNEVSTRIVELDRGKLTTYPGNYEDYIAMRAEKEVIEQKQNDKQRALYKQELAWMRAGAKARSTKQQARIHRFNDLEADVKQQQTQDKGELNLAYSRLGKQVYELDSLTKIINGRTLFQDITQIIQSGQRIGIVGPNGAGKTTMLNILSGEDQQFEGTLKIGQTVKVAYFKQTEETLNRDIRMIDYLREESEVAKEKDGTTVSITQLLERFLFPSSTHGKKIYKLSGGEQKRLYLLRLLVHQPNVLLLDEPTNDLDTETLTILEDYIASFGGSVITVSHDRYFLNKVAQEYWFIHDGMMERIVGSFEDYETYKKEKDKQLAIEKQATNTSKTQIKERKKTGLSYKEKREYESLMSRIEETEIRLSEIEQEMIEASADYAKIKDLTIEQQQLEQTYDEDITRWSELEELKEV
>NC_017353.1|WP_002479362.1|2212237_2213053_+|ZIP-family-metal-transporter
MEELFGSLPSYFQALIAGIITWLLTALGAAGVFIFNKVNGKVLASMQGFAAGIMIAASFWSLLQPSIEFKEGTTLPWLPAAIGFLLGGLFIRLLDAIIPHIHQRIGDKSHYREGVKTSLNKNTLLVLAITLHNIPEGLSIGVAFGGIASSNEHATFLGALGLAIGIGIQNIPEGAALSMPIRAAGASKWKAFNYGQASALVEPIFAILGAALIVVMTPVLPYALAFAAGAMIFVVVEELIPDSQSGNNTDLATLSLMIGFTIMMILDVALS
>NC_017353.1|WP_002479363.1|2213220_2215158_-|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS
MSIRKKKISLFTFFILTVLTVTLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALILSVFLFFKGKKAYWFIFIAGFLLTFLLYANVVYFRFFTDFLTFSTLNQASNVESMGGAVTASFKWYDFVYFIDTFIYLFILIFKNNWLDKRVFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIQNNQQKALASEDDLTKVLNYTKQKRTKANPEYFGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKQDFRYYPNFFHQTGQGKTSDSEFMMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYTSNVMHGDYKTFWNRDQIYRHFGIDKFYDATYYDMSEDNVVNLGLKDKEFFKESAGYQKKMKKPFYSHLITLTNHYPFTLDDKDADIDKPNTGDSTVDGYIQTAHYLDQALEQYVNDLKKEGLYDDSVIMIYGDHYGISENHNNAMEKLLGEQITPAKFTDLNRTGFWLKIPGKEGTVDKTYAGQMDVMPTILHLVGIDTKNYIMMGTDLLSKEHKDVIPFRNGDFITQNYKYVNGKIYSNKDNKLLEKKPKDFDKNKQQVEKDLEMSDSILNGDLFRFYNNPDFKKVNPAKYEYKTGPKGNQK
>NC_017353.1|WP_002479364.1|2215708_2216713_-|biotin-dependent-carboxyltransferase-family-protein
MSIKVIKEGLFSSFQDFGRRGYEHDGVIPGGALDELAHEIANRLVANDKNEATLEMTHKLPTLQFTEPTLIALTGSNFKAQTEHLTITPYKLYLIQAGDTLTFNETSRTSRVYLAVGGGFQLDEWLGSSSTDFNTHIGGFKGRTLQAGDTIQLKNNYSHRHTKLFENLAESNQTDWGIDGYALSFNYISDVFHVIKNKGTEDFDEATVQRFTLGDYKVTSKANRMGMYLQGESIKAYYEDMPAHQSVKRGTIQVKRDGTPIILLNDHYTLGSYPQIGTIASYHLSKLAQKPQGARLKFQFIDVETAEKNVVKYSHWVNQIFHAIEYRMKLEMLK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_017353_6	6.1\|750817\|27\|NC_017353\|CRISPRCasFinder	750817-750843	27	NC_017353.1	178741-178767	0	1.0
NC_017353_11	11.1\|2201801\|34\|NC_017353\|CRISPRCasFinder	2201801-2201834	34	NC_017353.1	43044-43077	0	1.0
NC_017353_11	11.1\|2201801\|34\|NC_017353\|CRISPRCasFinder	2201801-2201834	34	NC_017353.1	1263074-1263107	0	1.0
NC_017353_5	5.1\|698123\|17\|NC_017353\|PILER-CR	698123-698139	17	NC_017353.1	1015352-1015368	1	0.941
NC_017353_5	5.1\|698123\|17\|NC_017353\|PILER-CR	698123-698139	17	NC_017353.1	2497619-2497635	1	0.941
NC_017353_5	5.1\|698123\|17\|NC_017353\|PILER-CR	698123-698139	17	NC_017353.1	2497676-2497692	1	0.941
NC_017353_5	5.1\|698123\|17\|NC_017353\|PILER-CR	698123-698139	17	NC_017353.1	2232430-2232446	1	0.941
NC_017353_6	6.1\|750817\|27\|NC_017353\|CRISPRCasFinder	750817-750843	27	NC_017353.1	793638-793664	1	0.963
NC_017353_6	6.1\|750817\|27\|NC_017353\|CRISPRCasFinder	750817-750843	27	NC_017353.1	793695-793721	1	0.963
NC_017353_7	7.1\|786766\|34\|NC_017353\|CRISPRCasFinder	786766-786799	34	NC_017353.1	2178580-2178613	1	0.971
NC_017353_11	11.1\|2201801\|34\|NC_017353\|CRISPRCasFinder	2201801-2201834	34	NC_017353.1	1085333-1085366	1	0.971
NC_017353_11	11.1\|2201801\|34\|NC_017353\|CRISPRCasFinder	2201801-2201834	34	NC_017353.1	1103788-1103821	1	0.971
NC_017353_2	2.1\|395652\|32\|NC_017353\|CRISPRCasFinder	395652-395683	32	NC_017353.1	253735-253766	2	0.938
NC_017353_2	2.1\|395652\|32\|NC_017353\|CRISPRCasFinder	395652-395683	32	NC_017353.1	253792-253823	2	0.938
NC_017353_2	2.1\|395652\|32\|NC_017353\|CRISPRCasFinder	395652-395683	32	NC_017353.1	467497-467528	2	0.938
NC_017353_2	2.1\|395652\|32\|NC_017353\|CRISPRCasFinder	395652-395683	32	NC_017353.1	1583243-1583274	2	0.938
NC_017353_2	2.1\|395652\|32\|NC_017353\|CRISPRCasFinder	395652-395683	32	NC_017353.1	2464238-2464269	2	0.938
NC_017353_7	7.1\|786766\|34\|NC_017353\|CRISPRCasFinder	786766-786799	34	NC_017353.1	43044-43077	2	0.941
NC_017353_7	7.1\|786766\|34\|NC_017353\|CRISPRCasFinder	786766-786799	34	NC_017353.1	1103788-1103821	2	0.941
NC_017353_7	7.1\|786766\|34\|NC_017353\|CRISPRCasFinder	786766-786799	34	NC_017353.1	1263074-1263107	2	0.941
NC_017353_7	7.1\|786766\|34\|NC_017353\|CRISPRCasFinder	786766-786799	34	NC_017353.1	1852104-1852137	2	0.941

1. spacer 6.1|750817|27|NC_017353|CRISPRCasFinder matches to position: 178741-178767, mismatch: 0, identity: 1.0

aatgcaacaagcatttccacgaacaac	CRISPR spacer
aatgcaacaagcatttccacgaacaac	Protospacer
***************************

2. spacer 11.1|2201801|34|NC_017353|CRISPRCasFinder matches to position: 43044-43077, mismatch: 0, identity: 1.0

ggccccaacaaagagaaatgcgaaaagcatttcg	CRISPR spacer
ggccccaacaaagagaaatgcgaaaagcatttcg	Protospacer
**********************************

3. spacer 11.1|2201801|34|NC_017353|CRISPRCasFinder matches to position: 1263074-1263107, mismatch: 0, identity: 1.0

ggccccaacaaagagaaatgcgaaaagcatttcg	CRISPR spacer
ggccccaacaaagagaaatgcgaaaagcatttcg	Protospacer
**********************************

4. spacer 5.1|698123|17|NC_017353|PILER-CR matches to position: 1015352-1015368, mismatch: 1, identity: 0.941

ttggtgaatttcttatc	CRISPR spacer
ttggtgaatttcttttc	Protospacer
************** **

5. spacer 5.1|698123|17|NC_017353|PILER-CR matches to position: 2497619-2497635, mismatch: 1, identity: 0.941

ttggtgaatttcttatc	CRISPR spacer
ttggtgaatttcttttc	Protospacer
************** **

6. spacer 5.1|698123|17|NC_017353|PILER-CR matches to position: 2497676-2497692, mismatch: 1, identity: 0.941

ttggtgaatttcttatc	CRISPR spacer
ttggtgaatttcttttc	Protospacer
************** **

7. spacer 5.1|698123|17|NC_017353|PILER-CR matches to position: 2232430-2232446, mismatch: 1, identity: 0.941

ttggtgaatttcttatc	CRISPR spacer
ttggtgaatttcttgtc	Protospacer
**************.**

8. spacer 6.1|750817|27|NC_017353|CRISPRCasFinder matches to position: 793638-793664, mismatch: 1, identity: 0.963

aatgcaacaagcatttccacgaacaac	CRISPR spacer
aatgcaacaagcatttccacggacaac	Protospacer
*********************.*****

9. spacer 6.1|750817|27|NC_017353|CRISPRCasFinder matches to position: 793695-793721, mismatch: 1, identity: 0.963

aatgcaacaagcatttccacgaacaac	CRISPR spacer
aatgcaacaagcatttccacggacaac	Protospacer
*********************.*****

10. spacer 7.1|786766|34|NC_017353|CRISPRCasFinder matches to position: 2178580-2178613, mismatch: 1, identity: 0.971

ggccccaacagagagaaatacgaaaagcatttcg	CRISPR spacer
ggccccaacagagagaaatacgaaaagtatttcg	Protospacer
***************************.******

11. spacer 11.1|2201801|34|NC_017353|CRISPRCasFinder matches to position: 1085333-1085366, mismatch: 1, identity: 0.971

ggccccaacaaagagaaatgcgaaaagcatttcg	CRISPR spacer
ggccccaacaaaaagaaatgcgaaaagcatttcg	Protospacer
************.*********************

12. spacer 11.1|2201801|34|NC_017353|CRISPRCasFinder matches to position: 1103788-1103821, mismatch: 1, identity: 0.971

ggccccaacaaagagaaatgcgaaaagcatttcg	CRISPR spacer
ggccccaacaaagagaaattcgaaaagcatttcg	Protospacer
******************* **************

13. spacer 2.1|395652|32|NC_017353|CRISPRCasFinder matches to position: 253735-253766, mismatch: 2, identity: 0.938

tttctgctcgaaattctctttgttggggcccc	CRISPR spacer
tttcttctcgaaattctctttgctggggcccc	Protospacer
***** ****************.*********

14. spacer 2.1|395652|32|NC_017353|CRISPRCasFinder matches to position: 253792-253823, mismatch: 2, identity: 0.938

tttctgctcgaaattctctttgttggggcccc	CRISPR spacer
tttcttctcgaaattctctttgctggggcccc	Protospacer
***** ****************.*********

15. spacer 2.1|395652|32|NC_017353|CRISPRCasFinder matches to position: 467497-467528, mismatch: 2, identity: 0.938

tttctgctcgaaattctctttgttggggcccc	CRISPR spacer
tttcttgtcgaaattctctttgttggggcccc	Protospacer
*****  *************************

16. spacer 2.1|395652|32|NC_017353|CRISPRCasFinder matches to position: 1583243-1583274, mismatch: 2, identity: 0.938

tttctgctcgaaattctctttgttggggcccc	CRISPR spacer
tttcttctcgaaattctctctgttggggcccc	Protospacer
***** *************.************

17. spacer 2.1|395652|32|NC_017353|CRISPRCasFinder matches to position: 2464238-2464269, mismatch: 2, identity: 0.938

tttctgctcgaaattctctttgttggggcccc	CRISPR spacer
tttcttctcgaaattctctctgttggggcccc	Protospacer
***** *************.************

18. spacer 7.1|786766|34|NC_017353|CRISPRCasFinder matches to position: 43044-43077, mismatch: 2, identity: 0.941

ggccccaacagagagaaatacgaaaagcatttcg	CRISPR spacer
ggccccaacaaagagaaatgcgaaaagcatttcg	Protospacer
**********.********.**************

19. spacer 7.1|786766|34|NC_017353|CRISPRCasFinder matches to position: 1103788-1103821, mismatch: 2, identity: 0.941

ggccccaacagagagaaatacgaaaagcatttcg	CRISPR spacer
ggccccaacaaagagaaattcgaaaagcatttcg	Protospacer
**********.******** **************

20. spacer 7.1|786766|34|NC_017353|CRISPRCasFinder matches to position: 1263074-1263107, mismatch: 2, identity: 0.941

ggccccaacagagagaaatacgaaaagcatttcg	CRISPR spacer
ggccccaacaaagagaaatgcgaaaagcatttcg	Protospacer
**********.********.**************

21. spacer 7.1|786766|34|NC_017353|CRISPRCasFinder matches to position: 1852104-1852137, mismatch: 2, identity: 0.941

ggccccaacagagagaaatacgaaaagcatttcg	CRISPR spacer
ggcctcaacagagagaaatacgaaaagtatttcg	Protospacer
****.**********************.******

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017353_3	3.1\|577562\|30\|NC_017353\|CRISPRCasFinder	577562-577591	30	NZ_CP049244	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence	187193-187222	8	0.733
NC_017353_3	3.1\|577562\|30\|NC_017353\|CRISPRCasFinder	577562-577591	30	NZ_CP022118	Salmonella enterica subsp. enterica serovar Macclesfield str. S-1643 plasmid unnamed1, complete sequence	59911-59940	8	0.733
NC_017353_3	3.1\|577562\|30\|NC_017353\|CRISPRCasFinder	577562-577591	30	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	962765-962794	8	0.733
NC_017353_2	2.1\|395652\|32\|NC_017353\|CRISPRCasFinder	395652-395683	32	NZ_CP049244	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence	399493-399524	9	0.719
NC_017353_3	3.1\|577562\|30\|NC_017353\|CRISPRCasFinder	577562-577591	30	NZ_CP020539	Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence	485451-485480	9	0.7
NC_017353_11	11.1\|2201801\|34\|NC_017353\|CRISPRCasFinder	2201801-2201834	34	MN094788	Achromobacter phage Motura, complete genome	4294-4327	9	0.735

1. spacer 3.1|577562|30|NC_017353|CRISPRCasFinder matches to NZ_CP049244 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

aagaaatgcgacaagcatttccgcgaacaa	CRISPR spacer
tggaaatgcggcaagcatttctgcgacatc	Protospacer
 .********.**********.****

2. spacer 3.1|577562|30|NC_017353|CRISPRCasFinder matches to NZ_CP022118 (Salmonella enterica subsp. enterica serovar Macclesfield str. S-1643 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aagaaatgcgacaagcatttccgcgaacaa	CRISPR spacer
aaaaaaggcgacaagcatttccggactctt	Protospacer
**.*** **************** .  *

3. spacer 3.1|577562|30|NC_017353|CRISPRCasFinder matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 8, identity: 0.733

aagaaatgcgacaagcatttccgcgaacaa	CRISPR spacer
gaacgcggcgacgagcctttccgcgaacaa	Protospacer
.*. .  *****.*** *************

4. spacer 2.1|395652|32|NC_017353|CRISPRCasFinder matches to NZ_CP049244 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

tttctgctcgaaattctctttgttggggcccc	CRISPR spacer
ccgctgctcgcaattctttttgttggttctgc	Protospacer
.. ******* ******.********  *. *

5. spacer 3.1|577562|30|NC_017353|CRISPRCasFinder matches to NZ_CP020539 (Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence) position: , mismatch: 9, identity: 0.7

aagaaatgcgacaagcatttccgcgaacaa	CRISPR spacer
ttcggctgcgtcaagcatgtccgcgaacag	Protospacer
   .. **** ******* **********.

6. spacer 11.1|2201801|34|NC_017353|CRISPRCasFinder matches to MN094788 (Achromobacter phage Motura, complete genome) position: , mismatch: 9, identity: 0.735

ggccccaacaaagagaaatgcgaaaagcatttcg	CRISPR spacer
agttccaacaaagagaactgcgaacagcgcgtgg	Protospacer
.*..************* ****** ***.. * *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

887580 : 929038

Staphylococcus_phage(76.36%)

holin,head,plate,portal,capsid,tail,terminase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014533238.1\|887580_888963_-	recombinase family protein	A0A2H4JD28	uncultured_Caudovirales_phage	8.4e-165	63.1
WP_014533239.1\|889020_889569_-	hypothetical protein	A0A1W6JQH1	Staphylococcus_phage	1.9e-27	77.8
WP_014533240.1\|889590_890100_-	hypothetical protein	NA	NA	NA	NA
WP_014533241.1\|890112_890577_-	ImmA/IrrE family metallo-endopeptidase	A0A141VTQ3	Staphylococcus_phage	2.0e-49	62.3
WP_014533242.1\|890591_890915_-	helix-turn-helix transcriptional regulator	A0A0H3U2V8	Staphylococcus_phage	2.7e-42	85.0
WP_044019727.1\|891080_891329_+	helix-turn-helix transcriptional regulator	A0A141VTQ5	Staphylococcus_phage	4.5e-29	80.0
WP_014533244.1\|891343_892225_+	DUF3102 domain-containing protein	A0A2H4J4L1	uncultured_Caudovirales_phage	1.2e-71	72.1
WP_014533245.1\|892237_892732_+	ORF6C domain-containing protein	A0A2H4J854	uncultured_Caudovirales_phage	5.0e-35	62.3
WP_014533246.1\|892770_892932_+	hypothetical protein	A0A1J0MF99	Staphylococcus_phage	2.0e-14	77.4
WP_014533247.1\|892937_893201_-	CRISPR-associated protein Cas2	A0A1J0MFM9	Staphylococcus_phage	4.6e-40	89.7
WP_014533248.1\|893258_894014_+	phage antirepressor KilAC domain-containing protein	A0A0H4J326	Staphylococcus_phage	8.5e-135	95.2
WP_002478861.1\|894029_894173_+	hypothetical protein	A0A2I6PDG0	Staphylococcus_phage	9.6e-16	95.7
WP_014533249.1\|894182_894785_-	hypothetical protein	B7T096	Staphylococcus_virus	7.3e-97	92.9
WP_002478864.1\|895012_895192_+	hypothetical protein	NA	NA	NA	NA
WP_002478865.1\|895260_895746_+	siphovirus Gp157 family protein	H9A0R4	Staphylococcus_phage	1.8e-61	76.4
WP_002478866.1\|895746_896421_+	ERF family protein	I6T7Q2	Staphylococcus_virus	7.1e-109	91.0
WP_014533250.1\|896417_896834_+	single-stranded DNA-binding protein	G4KNN8	Staphylococcus_phage	6.9e-46	83.2
WP_014533251.1\|896848_897526_+	hypothetical protein	A0A141VTR7	Staphylococcus_phage	6.2e-113	86.4
WP_014533252.1\|897515_898319_+	conserved phage C-terminal domain-containing protein	A0A1W6JNM1	Staphylococcus_phage	3.6e-107	81.7
WP_014533253.1\|898331_899117_+	ATP-binding protein	A0A1W6JPS4	Staphylococcus_phage	1.1e-142	96.9
WP_014533254.1\|899113_899278_+	hypothetical protein	A0A1W6JNE8	Staphylococcus_phage	2.9e-16	79.2
WP_014533255.1\|899267_899510_+	hypothetical protein	A0A1W6JNF3	Staphylococcus_phage	3.8e-28	76.2
WP_002478873.1\|899518_899926_+	RusA family crossover junction endodeoxyribonuclease	A0A0N9SH85	Staphylococcus_phage	3.9e-54	73.3
WP_014533256.1\|899922_900237_+	hypothetical protein	A0A2H4JG42	uncultured_Caudovirales_phage	4.3e-16	83.0
WP_014533259.1\|900760_901132_+	hypothetical protein	H9A0S5	Staphylococcus_phage	4.9e-19	50.0
WP_002478878.1\|901132_901414_+	DUF1024 family protein	A0A2H4J2P4	uncultured_Caudovirales_phage	2.0e-25	65.9
WP_002478879.1\|901403_901565_+	hypothetical protein	NA	NA	NA	NA
WP_002478880.1\|901565_901991_+	dUTP diphosphatase	A0A2H4J7M9	uncultured_Caudovirales_phage	5.3e-70	95.0
WP_002478881.1\|902027_902180_+	DUF1381 domain-containing protein	NA	NA	NA	NA
WP_002478882.1\|902169_902337_+	hypothetical protein	NA	NA	NA	NA
WP_014533260.1\|902333_902477_+	hypothetical protein	A0A141VTT7	Staphylococcus_phage	3.5e-10	76.1
WP_014533261.1\|902480_902882_+	hypothetical protein	H9A0U2	Staphylococcus_phage	1.6e-63	91.7
WP_044019728.1\|903102_903531_+	hypothetical protein	A1EAE0	Streptococcus_phage	7.6e-24	46.1
WP_014533263.1\|903517_904798_+\|terminase	PBSX family phage terminase large subunit	Q8SDU9	Staphylococcus_phage	3.6e-218	85.4
WP_002478887.1\|904809_906339_+\|portal	phage portal protein	A0A1W6JNP8	Staphylococcus_phage	9.1e-245	82.4
WP_014533264.1\|906345_907296_+\|capsid	minor capsid protein	A0A1W6JNS6	Staphylococcus_phage	1.7e-145	79.7
WP_014533265.1\|907292_907445_+	hypothetical protein	A0A1W6JNP6	Staphylococcus_phage	2.4e-09	70.8
WP_173362267.1\|907431_907581_+	hypothetical protein	A0A1W6JNR0	Staphylococcus_phage	1.7e-10	74.0
WP_014533266.1\|907825_908434_+	DUF4355 domain-containing protein	A0A1W6JNT6	Staphylococcus_phage	1.7e-16	54.0
WP_002478891.1\|908451_909372_+\|capsid	phage major capsid protein	A0A1W6JNT3	Staphylococcus_phage	5.8e-154	89.5
WP_002478892.1\|909393_909663_+	hypothetical protein	A0A1W6JNX0	Staphylococcus_phage	2.3e-34	80.9
WP_002478893.1\|909664_909994_+\|head,tail	phage head-tail connector protein	A0A1W6JNR3	Staphylococcus_phage	6.6e-44	80.7
WP_014533267.1\|909990_910293_+	hypothetical protein	A0A1W6JNQ9	Staphylococcus_phage	2.1e-44	84.0
WP_014533268.1\|910294_910642_+	HK97 gp10 family phage protein	A0A1W6JNQ6	Staphylococcus_phage	4.7e-48	80.0
WP_002478896.1\|910653_911043_+	hypothetical protein	A0A1W6JNQ3	Staphylococcus_phage	7.1e-53	80.6
WP_002478897.1\|911090_911645_+\|tail	phage major tail protein, TP901-1 family	A0A1W6JNU0	Staphylococcus_phage	1.5e-88	94.0
WP_002478898.1\|911705_912065_+	hypothetical protein	A0A1W6JNQ1	Staphylococcus_phage	8.3e-56	91.6
WP_002478899.1\|912109_912454_+	hypothetical protein	A0A1W6JNR9	Staphylococcus_phage	3.9e-55	95.6
WP_014533269.1\|912468_916002_+\|tail	tail protein	H9A0P1	Staphylococcus_phage	6.5e-129	58.2
WP_002478901.1\|916013_916973_+\|tail	phage tail family protein	A0A1W6JNU3	Staphylococcus_phage	2.3e-169	90.3
WP_002478902.1\|916983_918219_+\|tail	phage tail protein	A0A1W6JNY1	Staphylococcus_phage	2.6e-213	88.5
WP_014533270.1\|918219_920094_+	DUF2817 domain-containing protein	A0A1W6JNS8	Staphylococcus_phage	0.0e+00	89.4
WP_014533271.1\|920107_921265_+\|plate	BppU family phage baseplate upper protein	A0A1W6JNR8	Staphylococcus_phage	6.8e-160	72.5
WP_014533272.1\|921280_921703_+	hypothetical protein	A0A1W6JNR2	Staphylococcus_phage	2.3e-49	66.2
WP_014533273.1\|921683_922082_+	hypothetical protein	A0A2H4J9S2	uncultured_Caudovirales_phage	4.6e-31	53.0
WP_014533274.1\|922133_924023_+	glucosaminidase domain-containing protein	A0A1W6JNR1	Staphylococcus_phage	2.0e-262	81.9
WP_014533275.1\|924076_926830_+\|plate	BppU family phage baseplate upper protein	Q4ZC48	Staphylococcus_virus	6.9e-219	53.0
WP_002478910.1\|926886_927159_+\|holin	phage holin	A0A2H4JHI3	uncultured_Caudovirales_phage	2.0e-38	85.6
WP_014533276.1\|927158_928568_+	N-acetylmuramoyl-L-alanine amidase	A0A2H4J4H5	uncultured_Caudovirales_phage	9.9e-238	84.2
WP_014533277.1\|928762_929038_+	hypothetical protein	C8CH39	Staphylococcus_phage	1.3e-05	48.1

DBSCAN-SWA_2

1201290 : 1231545

Staphylococcus_phage(96.15%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002458784.1\|1201290_1202685_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.5e-169	62.3
WP_002477998.1\|1202691_1203696_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	2.3e-95	51.7
WP_002458786.1\|1203692_1203950_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	1.2e-29	70.4
WP_002458787.1\|1204016_1204490_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	2.6e-49	60.6
WP_002477999.1\|1204470_1205244_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	6.5e-98	69.4
WP_002458789.1\|1205307_1206900_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	1.1e-274	86.0
WP_002458790.1\|1207271_1208468_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.7e-198	87.4
WP_002458791.1\|1208566_1209475_+	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	1.3e-102	76.6
WP_002478000.1\|1209589_1210423_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.4e-119	73.3
WP_002478001.1\|1210607_1210961_-	fluoride efflux transporter CrcB	NA	NA	NA	NA
WP_002478002.1\|1210957_1211323_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	2.0e-33	62.0
WP_002478003.1\|1211391_1211697_-	hypothetical protein	NA	NA	NA	NA
WP_002478004.1\|1211953_1212667_+	transaldolase	M1PR54	Cyanophage	1.1e-19	36.3
WP_002458797.1\|1212797_1213250_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	1.6e-16	43.6
WP_002458798.1\|1213230_1213677_-	competence protein ComK	NA	NA	NA	NA
WP_002478005.1\|1213692_1214163_-	sigma-70 family RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	1.6e-27	45.5
WP_002458800.1\|1214360_1214585_+	hypothetical protein	NA	NA	NA	NA
WP_002458801.1\|1214786_1215641_+	glucosaminidase domain-containing protein	A0A1W6JNR1	Staphylococcus_phage	7.5e-39	42.1
WP_002478006.1\|1216024_1217524_+	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	9.9e-18	77.2
WP_002478007.1\|1217835_1218942_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.4e-124	62.9
WP_002458804.1\|1218949_1219582_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.3e-77	70.5
WP_002478008.1\|1219594_1220776_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	2.9e-174	75.3
WP_002458806.1\|1220788_1221247_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	8.6e-58	80.9
WP_002478009.1\|1221324_1222311_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	2.7e-133	72.6
WP_002458809.1\|1223855_1224257_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_002458810.1\|1224307_1224871_-	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	3.5e-69	67.4
WP_002458811.1\|1224867_1225821_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	3.2e-70	86.1
WP_002478010.1\|1225924_1227100_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	1.8e-176	78.8
WP_014533288.1\|1227421_1229836_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	87.0
WP_002458814.1\|1229854_1230166_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	6.5e-33	68.0
WP_002478012.1\|1230285_1231545_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	3.7e-42	83.5

DBSCAN-SWA_3

1348325 : 1357344

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002478078.1\|1348325_1349330_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	3.8e-05	29.1
WP_002478079.1\|1349332_1350358_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_002478080.1\|1350376_1351516_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	4.2e-85	45.0
WP_002458927.1\|1351534_1351795_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	2.8e-05	39.3
WP_002478081.1\|1351980_1354269_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	2.8e-32	34.4
WP_002478082.1\|1354529_1356806_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	8.7e-66	29.0
WP_002458930.1\|1356825_1357344_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	1.4e-27	45.8

DBSCAN-SWA_4

1483022 : 1491719

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002459061.1\|1483022_1483754_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	1.1e-06	24.0
WP_012990840.1\|1483746_1484280_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	3.5e-10	29.1
WP_002478163.1\|1484282_1485020_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_002459064.1\|1485169_1485895_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.4e-48	43.5
WP_002478164.1\|1485878_1487627_+	HAMP domain-containing protein	A0A1V0SGX0	Hokovirus	1.5e-20	31.6
WP_002478165.1\|1488350_1488893_+	ECF transporter S component	NA	NA	NA	NA
WP_002449743.1\|1489034_1489283_-	ferredoxin	A0A127AYY7	Bacillus_phage	5.8e-16	49.3
WP_002459068.1\|1489393_1490353_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002459069.1\|1490339_1491719_+	ATP-dependent DNA helicase RecQ	J2YAJ8	Acanthamoeba_polyphaga_lentillevirus	1.6e-51	33.2

DBSCAN-SWA_5

1896184 : 1904654

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002478377.1\|1896184_1896751_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.4e-27	39.2
WP_002478378.1\|1896750_1897782_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	8.7e-66	44.1
WP_002459448.1\|1897774_1899259_-	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	3.2e-45	30.8
WP_002478379.1\|1899237_1901427_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.0e-135	37.7
WP_002478380.1\|1901419_1902091_-	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_002459451.1\|1902092_1902353_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_002478381.1\|1902352_1903057_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	4.0e-46	42.4
WP_002478382.1\|1903057_1904185_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_002478383.1\|1904171_1904654_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.8e-21	42.7

DBSCAN-SWA_6

2185982 : 2203835

uncultured_Caudovirales_phage(58.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014533350.1\|2185982_2186942_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	4.2e-06	62.0
WP_002492143.1\|2186922_2187900_-	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	5.8e-136	79.3
WP_002459737.1\|2188459_2189494_-	siderophore ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002459738.1\|2189610_2190393_-	ATP-binding cassette domain-containing protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	1.5e-14	31.2
WP_002479353.1\|2190389_2191349_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	4.1e-09	62.0
WP_002459740.1\|2191329_2192307_-	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.4e-144	81.4
WP_002459741.1\|2192675_2193644_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	5.7e-176	92.9
WP_002459742.1\|2193883_2195989_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_002459743.1\|2195951_2196350_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	4.3e-53	76.5
WP_014533353.1\|2197223_2198093_+	DMT family transporter	NA	NA	NA	NA
WP_002479355.1\|2198105_2198606_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	1.0e-51	70.8
WP_037553882.1\|2198890_2200396_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.2e-60	32.9
WP_002479357.1\|2200723_2201638_+	diacylglycerol kinase family lipid kinase	NA	NA	NA	NA
WP_002479359.1\|2202011_2202542_-	5'-3'-deoxyribonucleotidase	A0A0A0PKY7	Bacillus_phage	1.3e-28	37.8
WP_002459751.1\|2202779_2203835_-	histidinol-phosphate transaminase	A0A0H3TLT9	Faustovirus	3.0e-21	27.7

DBSCAN-SWA_7

2218356 : 2224977

Pandoravirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002459762.1\|2218356_2219508_-	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	6.0e-23	35.1
WP_002479366.1\|2219491_2220088_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.4e-39	44.5
WP_002459764.1\|2220423_2221095_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	7.9e-68	57.5
WP_002459765.1\|2221096_2221516_+	6-carboxytetrahydropterin synthase QueD	NA	NA	NA	NA
WP_002459766.1\|2221515_2222232_+	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	1.8e-49	40.7
WP_002459767.1\|2222330_2222921_+	hypothetical protein	NA	NA	NA	NA
WP_002479367.1\|2222961_2223984_-	glycosyltransferase family 2 protein	A0A192Y8W7	Salmonella_phage	4.2e-60	41.9
WP_002479368.1\|2224140_2224977_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	9.6e-63	44.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_017353

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection