CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_018077	Mycoplasma bovis HB0801, complete sequence	1 crisprs	NA	0	0	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_018077_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018077_1

242605-242687

Orphan

Consensus_repeat	Method
TCTGTACGAGATGTGCTTGAAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_018077_1

>merge|NC_018077|1|242605-242687|CRISPRCasFinder
TCTGTACGAGATGTGCTTGAAGAGCTTGATGAATCAGGCGAATCGCTTTGAGTTCCAGATTCTGTACGAGATGTGTTTGAAGA

>NC_018077|1|1|242605-242687|CRISPRCasFinder
TCTGTACGAGATGTGCTTGAAGA	GCTTGATGAATCAGGCGAATCGCTTTGAGTTCCAGAT
TCTGTACGAGATGTGTTTGAAGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_018077.1\|WP_013954652.1\|253209_253545_+\|HIT-family-protein	unknown	unknown	gnl\|CDD\|223611
NC_018077.1\|WP_013954646.1\|244898_245843_-\|endonuclease	unknown	unknown	gnl\|CDD\|367881
NC_018077.1\|WP_013954648.1\|247950_248505_-\|inorganic-diphosphatase	unknown	unknown	gnl\|CDD\|179388
NC_018077.1\|WP_013954636.1\|238485_239193_+\|hypothetical-protein	unknown	unknown	unknown
NC_018077.1\|WP_013954630.1\|229515_230913_+\|CvpA-family-protein	unknown	unknown	gnl\|CDD\|367140
NC_018077.1\|WP_038582854.1\|243445_244213_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223039
NC_018077.1\|WP_013954651.1\|251827_253210_+\|hypothetical-protein	unknown	unknown	unknown
NC_018077.1\|WP_013456603.1\|248583_248853_+\|30S-ribosomal-protein-S20	unknown	unknown	gnl\|CDD\|178943
NC_018077.1\|WP_013954647.1\|245941_247888_+\|transketolase	unknown	unknown	gnl\|CDD\|223100
NC_018077.1\|WP_013954653.1\|253663_254362_+\|hypothetical-protein	unknown	unknown	unknown
NC_018077.1\|WP_013954633.1\|235683_236613_+\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319818
NC_018077.1\|WP_013954635.1\|237518_238493_+\|DNA-cytosine-methyltransferase	unknown	unknown	gnl\|CDD\|223348
NC_018077.1\|WP_013954650.1\|249647_251816_+\|hypothetical-protein	unknown	unknown	unknown
NC_018077.1\|WP_013954638.1\|240234_240930_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	unknown	unknown	gnl\|CDD\|223434
NC_018077.1\|WP_013456076.1\|239662_239992_+\|hypothetical-protein	unknown	unknown	unknown
NC_018077.1\|WP_013954634.1\|236614_237331_+\|ribonuclease-HIII	unknown	unknown	gnl\|CDD\|260000
NC_018077.1\|WP_013954649.1\|248966_249554_-\|hypothetical-protein	unknown	unknown	unknown
NC_018077.1\|WP_014829885.1\|240913_241900_-\|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl\|CDD\|234929
NC_018077.1\|WP_013954632.1\|232956_235542_+\|DNA-topoisomerase-IV-subunit-A	unknown	unknown	gnl\|CDD\|235503
NC_018077.1\|WP_013954631.1\|231026_232943_+\|DNA-topoisomerase-IV-subunit-B	unknown	unknown	gnl\|CDD\|223265

Protein	Function_ID	Function_description	E-value
NC_018077.1\|WP_013954652.1\|253209_253545_+\|HIT-family-protein	gnl\|CDD\|223611	COG0537, Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only].	5.20672e-31
NC_018077.1\|WP_013954646.1\|244898_245843_-\|endonuclease	gnl\|CDD\|367881	pfam04231, Endonuclease_1, Endonuclease I. Bacterial periplasmic or secreted endonuclease I (EC:3.1.21.1) E. coli endonuclease I (EndoI) is a sequence independent endonuclease located in the periplasm. It is inhibited by different RNA species. It is thought to normally generate double strand breaks in DNA, except in the presence of high salt concentrations and RNA, when it generates single strand breaks in DNA. Its biological role is unknown. Other family members are known to be extracellular. This family also includes a non-specific, Mg2+ activated ribonuclease precursor.	5.57394e-50
NC_018077.1\|WP_013954648.1\|247950_248505_-\|inorganic-diphosphatase	gnl\|CDD\|179388	PRK02230, PRK02230, inorganic pyrophosphatase; Provisional.	6.84527e-119
NC_018077.1\|WP_013954631.1\|231026_232943_+\|DNA-topoisomerase-IV-subunit-B	gnl\|CDD\|223265	COG0187, GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit [DNA replication, recombination, and repair].	0
NC_018077.1\|WP_013954630.1\|229515_230913_+\|CvpA-family-protein	gnl\|CDD\|367140	pfam02674, Colicin_V, Colicin V production protein. Colicin V production protein is required in E. Coli for colicin V production from plasmid pColV-K30. This protein is coded for in the purF operon.	5.9383e-07
NC_018077.1\|WP_038582854.1\|243445_244213_-\|hypothetical-protein	gnl\|CDD\|223039	PHA03307, PHA03307, transcriptional regulator ICP4; Provisional.	5.22796e-06
NC_018077.1\|WP_013456603.1\|248583_248853_+\|30S-ribosomal-protein-S20	gnl\|CDD\|178943	PRK00239, rpsT, 30S ribosomal protein S20; Reviewed.	3.77072e-16
NC_018077.1\|WP_013954647.1\|245941_247888_+\|transketolase	gnl\|CDD\|223100	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism].	0
NC_018077.1\|WP_013954633.1\|235683_236613_+\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.19348e-56
NC_018077.1\|WP_013954635.1\|237518_238493_+\|DNA-cytosine-methyltransferase	gnl\|CDD\|223348	COG0270, Dcm, Site-specific DNA methylase [DNA replication, recombination, and repair].	2.47396e-81
NC_018077.1\|WP_013954638.1\|240234_240930_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	gnl\|CDD\|223434	COG0357, GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane].	1.24583e-40
NC_018077.1\|WP_013954634.1\|236614_237331_+\|ribonuclease-HIII	gnl\|CDD\|260000	cd06590, RNase_HII_bacteria_HIII_like, Bacterial type 2 ribonuclease, HII and HIII-like. This family includes type 2 RNases H from several bacteria, such as Bacillus subtilis, which have two different RNases, HII and HIII. RNases HIII are distinguished by having a large (70-90 residues) N-terminal extension of unknown function. In addition, the active site of RNase HIII differs from that of other RNases H; replacing the fourth residue (aspartate) of the acidic "DEDD" motif with a glutamate. Most prokaryotic and eukaryotic genomes contain multiple RNase H genes; however, no prokaryotic genomes contain the combination of both RNase HI and HIII. This mutual exclusive gene inheritance might be the result of functional redundancy of RNase HI and HIII in prokaryotes. Ribonuclease (RNase) H is classified into two families, type I (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type II (prokaryotic RNase HII and HIII, archaeal RNase HII and eukaryotic RNase H2/HII). RNase H endonucleolytically hydrolyzes an RNA strand when it is annealed to a complementary DNA strand in the presence of divalent cations, in DNA replication or repair.	1.55849e-72
NC_018077.1\|WP_014829885.1\|240913_241900_-\|ribose-phosphate-pyrophosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	2.84424e-164
NC_018077.1\|WP_013954632.1\|232956_235542_+\|DNA-topoisomerase-IV-subunit-A	gnl\|CDD\|235503	PRK05561, PRK05561, DNA topoisomerase 4 subunit A.	0

>NC_018077.1|WP_014829885.1|240913_241900_-|ribose-phosphate-pyrophosphokinase
MNNNNALLFGMPNCIKLAERISKMINIPLSTLTLTKFADGETMPVSDEAVRGKDVYIIASTSRPVNDNLMILYLFIDSLKRASAKSINIALAYYGYARQDRKASGRQPIGAKLVADFLETAGASKIITVDLHNSAIQGFFNIPIDDLKASFTLAKAIKRSHEKFTVVSPDHGGTVRARSLAELISNDIKISIIDKRRTGINQTEVMGLIGDVKDQNAVIIDDIIDTGGTIIKAAETLKQYGAKKIVIAATHGIFSKGFDIFENNPAVEKVIITDSIDNDELLDKYKKLEIVSLDRFLGSVIDCSINGKSISMLYDKFAKEIKENESHK
>NC_018077.1|WP_013954638.1|240234_240930_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG
MNHINKEYLLNKYSKQIPLLYRYAQMIYEKNKVMNICGFDSVDEIFNQGILGSILVFENAMNEYNHDFVNKKILDIGAGAGFPSVPLLIALDNKFELVIMESITKRCTFLESVKNEFNLNLTIINARAEEINDYNSYFDYICARAVGSVIKIYLMTNHHLAQNGYFILPKGKNYHAEIDEFKNKFTLEKDNISSFEYEDSINNENSSLVLIKKTKPTPRGWPWKWAKIKNY
>NC_018077.1|WP_013456076.1|239662_239992_+|hypothetical-protein
MSRTKKLSISYLITYPIAFIVTVVLLVLYGRQLLDFAQQKEGFTGNLALWTVYLLYAVVIVVPFIMLIINILLIFFNVGTIARILLIVGLFVPWCSFVGALIALIRPGK
>NC_018077.1|WP_013954636.1|238485_239193_+|hypothetical-protein
MNNYSEVAIELQSKLEEAINNIFEITNNEISINVEDVNILQRDNNSINSSTAIGYILEEYLIRKIEQYLSSPDCHFEFSMKPNNKANTSSYDFSLVYKDHLFYINLKANRNVNDAIAAINRLYSDYVEYEGKNPLHYLVFKTNYDIDKSKISNQNKIIIKGTYSFFLEQIDFSKGWKQDHRSWSPGGKLNSGRLIVSKNFFNENQIEISKISYEQTRAYLEEMFNKNFSVAEYEE
>NC_018077.1|WP_013954635.1|237518_238493_+|DNA-cytosine-methyltransferase
MGKRGIIDLFAGAGGLTLGFTQNNFDILDTIEFWQPAVDTYNFNFKKNVVAKDITDSEVRNELESNWKNKTDLVIGGFPCQGFSLAGRRSKDDERNQLYKYTIDVISRLQPYGFVLENVKGILSFRESDNELVVDKIQKMLAKENYYTKFILLDSSNFGVPQKRERVIFIGCKDKEKVDKVISLLSKHKEKIVTVFDAIGHLEKVTDDKEIPNHIFSKHSEEIKERFMKLKEGESLSKSFSDAFRKLSYDKPSPTVKENHGGVHVHPVLPRVLTPRELANLQSFPEDFIFLGTKSNVLKQIGNAVPVKLSYEIAKIVNKVFFNE
>NC_018077.1|WP_013954634.1|236614_237331_+|ribonuclease-HIII
MQFLDLDVESSLLENKSIIGVDEVGVGDYFGPLCASAVFIDAQNVNKVAELGIKDSKKLSDKRIKELALKLKNSGLIHYSLAHLNPSGYNKLNKSYNANILKMFVHLKAINSVVFKLKNIKYDYIFIDKYASVDNMLKYYNELVINNNWANFQEINEDILIANKAESYSISVAAASILARDQFLTLVSKMNDEYNTVFPLGAGPKVNAFAKDFFAKHSYDEEVIKKTCKKSFKMNILN
>NC_018077.1|WP_013954633.1|235683_236613_+|Cof-type-HAD-IIB-family-hydrolase
MSTLTNNKKEKFLFAIDLDGTLLSSSRENIVPENCIKAIQRAKDEGHVVCIFTGRPWRSTKPIYDMLGLNTVVSNYNGAQIHNPKDDNFIPHIKYLNLNEMLYILGDQKVKKEISNLAIEGPGWVQLEHRDDDIEAVFGFSSAEKFTVGINLNKVPLSPTGIVFDVKETTDAEELRRYLRARYGDLGEFSYWSKGEGLTPVFDITNVTVNKGRALSLLSRYYGVDLDHTIAFGDGFNDVPMFKVATVSVVLGNAADLVKRHATVRLKKTNKEGGVGDYINKFLDNPEKEIAKSKAMALKMRKVSIQEEE
>NC_018077.1|WP_013954632.1|232956_235542_+|DNA-topoisomerase-IV-subunit-A
MNKKKEQQLNDLLSKIVRENLDTVVADRFSRYSKYVIQQRALPDVRDGLKPVQRRILYSMYDLGLQHNKPFKKSARVVGDVIGKYHPHGDSSIYDAMVRMGQEWKMGHTLVEMHGNVGSIDDDPAAAMRYTEARLSEIADYVIGDIKKNTVKFAPNFDDSEKEPVVMPVLIPNLLINGSTGIASGFATEMPPHNLNEILDAAIAKIKNPAIELSKLAKIIQGPDFPTGGVIYGTDGIYEAFERGKGRITLASRYNVYSDNKYKYIEITEIPYGVIKSKLVHEIDLIVDSEEVAGLIEVKDQTDRNGINILITLDKNVNENVIVNYLFLKTQMRIYYNYNNVVIDNHTPKTMGISALLDAYLKHVKDVKVKTIEFDLIKHKARLEIVIGFLKVAKITDKVIEVIRKSEDSKQGVIDNLMSAFDFTLNQATAIAELRLYKLSKTDEHTFMFEKQELEEKIKQCELLLTNPDEFNNYLVSLFRDLKHKFGRIRRTSIEIEQINSSVNQEDLVKEEEVFLGISKFGYIKKVSKKTYESNLITTYGIKEDDNILFYDIASSLDKLLLFTNLGNYAYLPVFKVNESKWKEFGIHLSDFVDLSSGEEIVSVIKVSDFDVTNYVCMFTKKGQGKKVLLKDFDVSRFSKTFVAMKLKNDDELISAKLSNGLKDVLLITKNNFASLYSENDVPIYGLKSNGNKACYLANGDELVSFTVVKPNDSVALVSQSNKVRLINVSEISRVSKQNKGVSIFSKGRLNNAIVQCDPLLDETKLLLVNNQGQAHFEKIQNYVKQASTKFINFDADDIRTISLISNYSSTTNDNEFHSYEKESSDENQLMNKAIETKNSIDLSIDEILSKVDELLKKDKK
>NC_018077.1|WP_013954631.1|231026_232943_+|DNA-topoisomerase-IV-subunit-B
MSNSNYDASSIQQLKGLEAVRKRPGMYIGSTDVNGLHHLIWEIVDNSIDEALAGEANEIAVILKNDGSVVVSDNGRGIPVGKTPSGKSAVELVFTELHAGGKFNEGAYKTSGGLHGVGSSVVNALSNKLKCLVYRDKHVYETIFENGDNIVQKTHIIGSTNKRGTLIQFWPNYEIFKKAKFNFETIAERLRESSFLISNLSIKLLDEQSGKSEEFKYSNGIKAFVEFINDSKTALFNVYSFKTVVNEIEIECGFQYTDGFNETILSFVNNVKTRDGGTHEIGLKSAITKTFNDFALDEKVLKGKNTFDGEDVREGLTVVLSVKIPEKFLEFVSQTKDKLGTPEAKSAVEEAVSKNLKTWITENKQIAKKILDKIKRASDSRESARKARLEARKTKSALKERQILSGKLTPAQTKNVKEKELFLVEGDSAGGSAKSGRDRKFQAILPLRGKVINTEKARLIDILKNEEINTIINAIGAGIGVDFDINKIQYDKVIIMTDADTDGAHIQILLLTFFFRHMRKLIEEGKVYIALPPLFKLSINKGQKKILYAWDEDELKELLQSKMKGAEVQRYKGLGEMNADQLWETTMNPETRTLIQVRIQDAALAERRVSTLMGDNVDSRKEWINKNVNFTMEDDFEI
>NC_018077.1|WP_013954630.1|229515_230913_+|CvpA-family-protein
MKIIESLENIAFNSWSILIPIILVIFIVILAIVSGLRRGIYGGLIILLFGLSGWIIGIFAAKPLVDVIVIKTKITLPGNKQIDAEILRKMFYGIAMFVIQILFLIVGEIISLLLRKWIKKPLKNMRENKVSSVGSRSLGAVLSTAGIVPCAILTANVTGFLTTNNKVIDANDKMLNYISFKKAEGVSKYTPGLIASAKIGNDLLNASSGSKLDETVIGAFEWYLQQFANPDNYVLLSVSKDGQAKPIISTNALKNINRKEEQEKVLQGLIPFILGDSSVKKNGITLFFNFNTSSAGAFKYDSNSGKIEINTDNSENTQLKVKNIGKISNIFQLYTATPESFRILEYLSKLGLKDAKASEGFDEIYSLVDQTEPVWDILNAAQLKFNMNPSYRIKVYDREYVKRMKDILFDLFEKNTGGKFKYDRKELNEEKMKSWVTIQTIHQKIYWIVSSVIDNVFITPENVSN
>NC_018077.1|WP_038582854.1|243445_244213_-|hypothetical-protein
MPNKVVITGFKDSLINENIIIKPEPIPPINRENPIMKDAETSTNDESSSSSTSRTDSGTQSDSPASSSSSSTSRTDSGTQSDSPASSSSSSTSRTDSGTQSDSPASSEPEKANSELSNERKIKEKGYRLNELTAYPYDLIDVDDDANKDELAKKLNDVITHKNGAIAIVGGSFFSKCNNLQLTGLSINKSIKSETKSQISTHNKLIGFFEGSDGYGIKVGHHGEANSKKYLFKWRLVKEDGNFGPKVYEQIIDLS
>NC_018077.1|WP_013954646.1|244898_245843_-|endonuclease
MMNSKMIKHKFLVSLGLISAPVLSLTVLSSTGCNNKNSTTDDNYLIPEKSFYEKSNYYDSLEGLNGNKLYSELIKIQHNHLSGIKSYRYLKTIYKDAFKDLYYEKDGSLLDIYSENPIGKDPYNYSFNDSGSSAKSEGLGFNREHLVPQSWFKREKLARQDAHHVWPADILVNNKRDNYPFGKVTNAIFTSKNGTKIDSYLAEPIDEFKGDIARAHLYFAITHASRYKMHNKGNEVFKFFDNKPLVNKYFDTYTKWAKKDQINLFDIVRNNEIAKHQNGLRNPFSDYPELIDLIINPGNKVFVNKGILKSNIAV
>NC_018077.1|WP_013954647.1|245941_247888_+|transketolase
MNINQKVVASMQAIALDSINNAGGGHIGSAIDISPIMYAVVAKHMKISADHPKWISRDRLILSAGHASMSFYSMMHFLGLLSLDEMKNHKRKHSKTPSHPETDAFDFVDASTGPLGQGIAMGVGMAIAEKKMSLKINKGNTKVIDNYTYVIAGDGCLQEGITHEALQIASVMKLNKFILIHDYNKIQLDTKVSDVSNVDLLAYFKALNFNVIEINEASYDNIDKAITEAKKSDRPTYIMVHNIIAPFTPFENTTKGHHGILNSEQTIEFKKAIGLENKAPFEYDSDVYEYGRTIMANKAKSYEEWLVELDNHKKQFPWIHSLLLETINNETNYDFSNILVKQDDLAIRDYFKAFSEIVDFSYPFLIGGGADVGSSTKVRFADSILDYGQRIDYGVREFAMTAINNGINLYGGLKTADSTFLAFSDYAKGALRLGGIMKLPAVHLYSHDSYLVGDDGPTHQPIEQVTVLRSIPNLLVIRPCDKYELVMGLNYAYNNTSTQVAIIGTRQPIKTMHSSKFSEFMAASLVYENKEFDISILSSGSEVELAYKTAVELKNHGIIANVISVPVLQKLVDNDELAIKLKLDKKPMFAIEASNDPLWYKLSKYNKIDGHFASEYGFSDKGNVVYDSMGFNVNSIVDKVKQFLSKNA
>NC_018077.1|WP_013954648.1|247950_248505_-|inorganic-diphosphatase
MSNVIEIRIEIPKNSNIKYEYNREDGQIHVDRILRGDFKYPCNYGFIPNALDWDGDELDVLLYSPETFIPGVVVNARIIGAMKMNDSGETDTKLIAVHDDDYRLANINSLKELPEPFLLDIETFFNNYKNWKKPNLTKVLGFEDEKWAFAELEECKELMDKYGKMPKKEFVAKMMKEHPEKYTF
>NC_018077.1|WP_013456603.1|248583_248853_+|30S-ribosomal-protein-S20
MANIKSKVKSIAKQEEFRQRNNAMKTRVRKAIRAAREAVLAKEEGFEKKVFEAHSIIATAVQKGIYHPNKGARKSSRLDHFVNEQKSKQ
>NC_018077.1|WP_013954649.1|248966_249554_-|hypothetical-protein
MQMIIKTTAIEVLRELQKLLESENINYSLGLSNYYEYKNKPELFLINDIEVCLWHKDFYFLLKKYPNHFILPENLPFKSLAPYYKFQGSSIKINIIVGTSDEKINYWYKFRNYKRLIYWGNSKKHWFYYFLGHRTQRVYLHDLVNDLVVERYTKFIILNSEIDKFKAFDNLNFNKRFFVTEKGITIPFFEPFRSL
>NC_018077.1|WP_013954650.1|249647_251816_+|hypothetical-protein
MGKKKTPFFERLLQKNAEQENKNKTTGKSKKSRSWKIATTSTVLVLAVATGITVPLVINSTKKNFIDGYASNTNVASAKIGDHNLDLNFGDFKDIYQNHNTSTSEERLKEIDKIILYYLYDQEQKASAEYQKLWNDSKRSDEKDNNSFRLPTLDELKTKFKNELVDIENNMKLQFGTANWQTEFNKHLVQKYNGAKNIDEAVKNKTFEHIKSDALRRFRLINGDSKKDEIERKGKDGKHVFGWWHKDNNENKFIELEDKSKLALATDSFVFKDSYKSIDPFIDSYIANEKPRIISEFTIPGIAPAKKNEKWKIDKNIFLRYLFYAKEGTFGLSKVTEGYNVVKEKFNSFDHYIKSVVDKANGKNILPDEAIQYSSILNMFSTSKEDIKKNWGTSGLTSISELVTGDNFQKFLANNPKLLFGENYSSGSTNGNKPKEIELFEKIKEISEKIAEVAKSSNGMSGSSSTGSSSNNNGALISNNTQATEYNTMLEKFFTEVNESQNKGLTEKVFEENILKKFVAIFEDKEKIQTVYKVKFNGNNIGAKNVTGILSPEGFKLLIFGDEIKKDELVKMIKNDFILNNKYKKQLGVRYNALQKLNKQLSRNEYILKMLQDNEFKEYLKTQNNNFATDQNGKKLENVKYNEQSIKDLITSSTAAIQFDKISNFIKLSKAAATWIETRAKNNYDELFELKDGKAYFKHNKDKTAASLVLEYLKKQFNLEAK
>NC_018077.1|WP_013954651.1|251827_253210_+|hypothetical-protein
MKKISKKLLASLSLFTIPSVAIISAKCGNDVETTERLNQQKDLKDAKRVTELEEIWKNFALSYIYKIKPSNKHDAKSWKQNFEKEFQNQQSQLFKDSYDAYKIFALDQLSKNEYYFVEKSLEWKKNDVFKSNPFNWISTKNFPGETDQKDFIRIWMEDKTGIRKEINNMLLVKAYFDISELKKLQTIANNIANAGKADKDKSKDQKFEYFVGGKDAKFDLDHYNLVKYAFENKYIQLWKRTFDDKTTSNDVFTRKEIKNTISSKDDFNAFFKDTAEAEKKAKEWEIITKNNEDKELQGYAGIQKDPGTYGLNWNETDNKRRVTGSGTYGVYDALNSILISFNDLASKSSVGVKDKDGKSIVSYINQIVPVGKKIKLKTKEDYTKDKVEDSKLKETEVLSFEGTIYKEYLNKLAYLFYGKDSKNLLEKAIEAFAHLGVKIKVNKEIAPLYEQLKNKVWVEK
>NC_018077.1|WP_013954652.1|253209_253545_+|HIT-family-protein
MDDLFLKIISGEEEGKIFYEDEYCVAFYDKFPIQPGHFLVVPRIKSKNIAEADDFTAGHLINTARKLGKQEVLDKGIAGFKILINTGRSADQSIFHTHVHVIPYKEKSKDN
>NC_018077.1|WP_013954653.1|253663_254362_+|hypothetical-protein
MNKRKLLLMSSLMSVAPIMVAAKCNPDSDNIVEFRLGIKDLNLRFANYGAFSSKELDKMLKQKPLKDGEFTVVYPSQEELEKEAKIIRDFFEKEETKKIPSYQTIYKETYETIVLGKRPVMLSDFTNEYLWSRDLVKIIDNGSIKNKNKLKLIINQFIDNANGSTTAHFRIEHSDDQRIYEVVGDSNGYIIQFNGKLKTISPNHYHLTKEIIENNKGNLAVLLKANETTQRK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

77393 : 88754

Bodo_saltans_virus(28.57%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013954527.1\|77393_78374_+	lipoate--protein ligase	A0A2H4UVX5	Bodo_saltans_virus	3.9e-15	27.1
WP_013954528.1\|78377_79199_+	alpha/beta hydrolase	G9E3U1	Emiliania_huxleyi_virus	2.3e-08	32.5
WP_013954529.1\|79282_80047_+	hypothetical protein	NA	NA	NA	NA
WP_013954530.1\|80039_81020_+	aspartate--ammonia ligase	A0A1C9C5F0	Heterosigma_akashiwo_virus	8.1e-53	40.6
WP_013954531.1\|81144_85521_+	PolC-type DNA polymerase III	A0A0K2SUJ2	Clostridium_phage	6.2e-12	31.8
WP_013954532.1\|85926_87150_+	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	1.5e-61	35.1
WP_013456569.1\|87139_88105_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2H4UW22	Bodo_saltans_virus	3.6e-29	40.9
WP_013954533.1\|88094_88754_+	uracil-DNA glycosylase	A0A068EP41	Falconid_herpesvirus	1.6e-28	36.4

DBSCAN-SWA_2

147606 : 157213

Mycoplasma_phage(57.14%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013455927.1\|147606_148623_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	8.4e-37	33.6
WP_014829869.1\|148950_150792_-	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	2.7e-17	19.1
WP_013954581.1\|151053_152466_+	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	1.6e-81	68.7
WP_013954582.1\|152449_153286_+	ABC transporter permease	Q6GZ02	Mycoplasma_phage	1.5e-87	62.0
WP_013954583.1\|153278_154172_+	spermidine/putrescine ABC transporter permease	Q6GZ01	Mycoplasma_phage	2.1e-92	62.1
WP_013954584.1\|154158_156060_+	membrane protein	Q6GZ00	Mycoplasma_phage	1.8e-80	34.7
WP_013455927.1\|156196_157213_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	8.4e-37	33.6

DBSCAN-SWA_3

257221 : 299568

Hokovirus(10.0%)

tRNA,transposase,integrase

attL 266943:267002|attR 297963:299590

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014829889.1\|257221_258772_-\|tRNA	methionine--tRNA ligase	A0A1V0SEZ7	Hokovirus	1.9e-80	35.7
WP_075270989.1\|258774_259560_-\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_013456627.1\|259580_261770_-	ribonuclease R	Q0GXV6	Lactococcus_phage	1.0e-71	33.5
WP_013456572.1\|261772_262015_-	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_013456283.1\|262357_262945_+	guanylate kinase	A0A0M5KCK5	Mollivirus	1.2e-08	38.6
WP_013456579.1\|262950_263703_+	serine/threonine-protein phosphatase	NA	NA	NA	NA
WP_013456514.1\|263720_264719_+	serine/threonine protein kinase	Q85453	Moloney_murine_sarcoma_virus	4.3e-17	32.2
WP_013456585.1\|264730_265576_+	ribosome small subunit-dependent GTPase A	NA	NA	NA	NA
WP_013455939.1\|265562_266225_+	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
266943:267002	attL	NA	NA	NA	NA
WP_013954660.1\|267159_268548_+\|transposase	transposase	NA	NA	NA	NA
WP_013954661.1\|268716_270942_-	AAA family ATPase	A0A218KCE8	Bacillus_phage	3.4e-30	27.7
WP_013456112.1\|271087_272521_-\|transposase	transposase	NA	NA	NA	NA
WP_013954662.1\|272993_274037_+	AAA family ATPase	A0A2H4UTU5	Bodo_saltans_virus	9.9e-09	29.0
WP_013954663.1\|274038_276309_+	S8 family peptidase	NA	NA	NA	NA
WP_013954664.1\|276538_279679_+	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	2.3e-24	24.8
WP_013954665.1\|279680_281321_+	SAM-dependent DNA methyltransferase	NA	NA	NA	NA
WP_013954666.1\|281307_281859_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_013954667.1\|281855_282548_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_013954668.1\|282726_283902_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_013954669.1\|283975_284944_+\|integrase	tyrosine-type recombinase/integrase	A0A2H4JAA2	uncultured_Caudovirales_phage	3.8e-31	29.2
WP_078086164.1\|285308_286910_-\|transposase	IS1634-like element ISMbov3 family transposase	NA	NA	NA	NA
WP_078086149.1\|287431_288214_+	hypothetical protein	NA	NA	NA	NA
WP_013954672.1\|288206_289364_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_013954673.1\|290309_291929_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	5.9e-109	39.8
WP_013954674.1\|292168_294835_+\|tRNA	isoleucine--tRNA ligase	A0A2I2L3Y0	Orpheovirus	4.2e-80	27.3
WP_013954675.1\|294847_295558_+	signal peptidase II	NA	NA	NA	NA
WP_078086167.1\|295818_297420_-\|transposase	IS1634-like element ISMbov3 family transposase	NA	NA	NA	NA
WP_013954660.1\|298179_299568_+\|transposase	transposase	NA	NA	NA	NA
297963:299590	attR	NA	NA	NA	NA

DBSCAN-SWA_4

923151 : 987753

Bacillus_virus(18.18%)

protease,transposase,tRNA,integrase

attL 922818:922869|attR 950414:950465

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
922818:922869	attL	NA	NA	NA	NA
WP_078086180.1\|923151_924180_+\|transposase	IS30-like element ISMbov1 family transposase	A0A2K9V2S9	Faecalibacterium_phage	6.5e-21	33.3
WP_013955061.1\|924390_925398_+	ECF transporter S component	NA	NA	NA	NA
WP_014829989.1\|925943_926594_+	variable surface lipoprotein	NA	NA	NA	NA
WP_014829990.1\|926769_927330_+	variable surface lipoprotein	NA	NA	NA	NA
WP_014829993.1\|929968_930928_+	variable surface lipoprotein	NA	NA	NA	NA
WP_014829994.1\|930970_931804_-	variable surface lipoprotein	NA	NA	NA	NA
WP_014829995.1\|931923_932784_-	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_013456322.1\|932776_933391_-	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	NA	NA	NA	NA
WP_013456123.1\|933802_934552_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_013955063.1\|934950_936795_+	ribonuclease J	NA	NA	NA	NA
WP_013955064.1\|936929_938081_+	hypothetical protein	NA	NA	NA	NA
WP_014829996.1\|938270_940688_+	DUF2779 domain-containing protein	NA	NA	NA	NA
WP_013955066.1\|940705_941014_-	hypothetical protein	NA	NA	NA	NA
WP_013955067.1\|941311_942733_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_013955068.1\|942725_944039_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_013955069.1\|944038_944344_-\|tRNA	glutamyl-tRNA(Gln) amidotransferase	NA	NA	NA	NA
WP_013955070.1\|944349_945204_-	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_013456616.1\|945215_945794_-	segregation/condensation protein B	A0A1B1IVT7	uncultured_Mediterranean_phage	1.2e-11	29.7
WP_013955071.1\|945783_946545_-	segregation/condensation protein A	NA	NA	NA	NA
WP_013456430.1\|946537_947278_-	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_013456524.1\|947287_947602_-	4'-phosphopantetheinyl transferase superfamily protein	NA	NA	NA	NA
WP_013456382.1\|947775_949086_-	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_013456261.1\|949088_949754_-	(d)CMP kinase	NA	NA	NA	NA
WP_014829997.1\|949824_950286_-	hypothetical protein	NA	NA	NA	NA
WP_013955073.1\|950573_951707_-	DnaJ domain-containing protein	A0A1V0SBY2	Catovirus	3.0e-27	32.2
950414:950465	attR	NA	NA	NA	NA
WP_013955074.1\|951944_952286_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_013955075.1\|952459_953695_-\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	3.3e-59	33.2
WP_013955076.1\|953705_954308_-\|tRNA	tRNA-binding protein	NA	NA	NA	NA
WP_013456246.1\|954369_955272_+	DegV family protein	NA	NA	NA	NA
WP_014829999.1\|955432_955666_-	acyl carrier protein	NA	NA	NA	NA
WP_013955078.1\|955705_956428_-	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_013456073.1\|956427_957504_-	peptide chain release factor 1	NA	NA	NA	NA
WP_013955080.1\|957629_958202_-	Fic family protein	NA	NA	NA	NA
WP_013955081.1\|958223_959645_-	YitT family protein	NA	NA	NA	NA
WP_013954660.1\|961099_962488_-\|transposase	transposase	NA	NA	NA	NA
WP_013955084.1\|962803_964771_+	type IIA DNA topoisomerase subunit B	G3M9Z3	Bacillus_virus	8.7e-131	41.5
WP_013955085.1\|964893_965208_+	thioredoxin family protein	A0A1X9I9P5	Staphylococcus_phage	1.7e-12	39.0
WP_013955086.1\|965260_965707_+	SsrA-binding protein	W5RAM5	Staphylococcus_phage	1.8e-12	37.4
WP_078086167.1\|967049_968651_+\|transposase	IS1634-like element ISMbov3 family transposase	NA	NA	NA	NA
WP_013955090.1\|968955_969945_-	DUF285 domain-containing protein	NA	NA	NA	NA
WP_013456532.1\|970405_971365_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_013955092.1\|971560_971956_+	hypothetical protein	NA	NA	NA	NA
WP_013955093.1\|972134_973379_+\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	1.1e-09	27.3
WP_013955094.1\|973496_976205_-	magnesium-translocating P-type ATPase	A0A1J0FA34	Only_Syngen_Nebraska_virus	3.7e-47	26.1
WP_013955095.1\|976325_977414_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.2e-14	29.7
WP_013955097.1\|985722_987753_-\|protease	ATP-dependent zinc metalloprotease FtsH	M4QMW8	Micromonas_pusilla_virus	3.8e-105	46.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage