CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_018081	Enterococcus hirae ATCC 9790, complete sequence	2 crisprs	cas2,DEDDh,DinG,cas3,cas9,cas1,csn2,cas14j,csa3	0	1	5	0
NC_015845	Enterococcus hirae ATCC 9790 plasmid pTG9790, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_018081_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018081_1

513137-513243

Orphan

Consensus_repeat	Method
CCAAGTATTGTTCATCATCTACTCACTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_018081_1

>merge|NC_018081|1|513137-513243|CRISPRCasFinder
CCAAGTATTGTTCATCATCTACTCACTTCGTTCTTAGTGATTCACTTCGCTTGAGAGGGAACTTCGCTCACTCTGTTCGCCAAGTATTGTTCATCATCTATTCACTT

>NC_018081|1|1|513137-513243|CRISPRCasFinder
CCAAGTATTGTTCATCATCTACTCACTT	CGTTCTTAGTGATTCACTTCGCTTGAGAGGGAACTTCGCTCACTCTGTTCG
CCAAGTATTGTTCATCATCTATTCACTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_018081.1\|WP_010738250.1\|507324_507609_-\|hypothetical-protein	unknown	unknown	unknown
NC_018081.1\|WP_010720151.1\|514252_514675_-\|50S-ribosomal-protein-L11	unknown	unknown	gnl\|CDD\|234661
NC_018081.1\|WP_010738505.1\|509399_510479_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|226406
NC_018081.1\|WP_010738504.1\|509022_509259_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|224937
NC_018081.1\|WP_010738509.1\|517014_517899_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|227151
NC_018081.1\|WP_010738506.1\|510582_510897_+\|hypothetical-protein	unknown	unknown	unknown
NC_018081.1\|WP_010738507.1\|510909_512055_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NC_018081.1\|WP_010738511.1\|520141_520645_-\|QueT-transporter-family-protein	unknown	unknown	gnl\|CDD\|377623
NC_018081.1\|WP_010720149.1\|512577_513081_-\|50S-ribosomal-protein-L10	unknown	unknown	gnl\|CDD\|234632
NC_018081.1\|WP_002294578.1\|518976_519129_-\|50S-ribosomal-protein-L33	unknown	unknown	gnl\|CDD\|234783
NC_018081.1\|WP_010738502.1\|508046_508787_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225484
NC_018081.1\|WP_010720152.1\|515213_515882_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	unknown	unknown	gnl\|CDD\|224674
NC_018081.1\|WP_010720158.1\|518787_518958_-\|preprotein-translocase-subunit-SecE	unknown	unknown	gnl\|CDD\|376355
NC_018081.1\|WP_010738503.1\|508788_509022_+\|hypothetical-protein	unknown	unknown	unknown
NC_018081.1\|WP_010738508.1\|515895_516762_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl\|CDD\|129801
NC_018081.1\|WP_010720157.1\|518142_518688_-\|transcription-termination/antitermination-protein-NusG	unknown	unknown	gnl\|CDD\|180161
NC_018081.1\|WP_010720150.1\|513459_514149_-\|50S-ribosomal-protein-L1	unknown	unknown	gnl\|CDD\|180071
NC_018081.1\|WP_010720148.1\|512156_512525_-\|50S-ribosomal-protein-L7/L12	unknown	unknown	gnl\|CDD\|234671
NC_018081.1\|WP_010738510.1\|519289_519931_+\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341358
NC_018081.1\|WP_010738501.1\|507664_507883_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_018081.1\|WP_010720149.1\|512577_513081_-\|50S-ribosomal-protein-L10	gnl\|CDD\|234632	PRK00099, rplJ, 50S ribosomal protein L10; Reviewed.	2.17032e-67
NC_018081.1\|WP_010720151.1\|514252_514675_-\|50S-ribosomal-protein-L11	gnl\|CDD\|234661	PRK00140, rplK, 50S ribosomal protein L11; Validated.	9.72997e-95
NC_018081.1\|WP_010738505.1\|509399_510479_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|226406	COG3889, COG3889, Predicted solute binding protein [General function prediction only].	3.63929e-05
NC_018081.1\|WP_010738504.1\|509022_509259_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|224937	COG2026, RelE, Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning].	1.08934e-05
NC_018081.1\|WP_010738509.1\|517014_517899_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|227151	COG4814, COG4814, Uncharacterized protein with an alpha/beta hydrolase fold [General function prediction only].	1.43087e-78
NC_018081.1\|WP_010738507.1\|510909_512055_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.39726e-51
NC_018081.1\|WP_010738511.1\|520141_520645_-\|QueT-transporter-family-protein	gnl\|CDD\|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	6.27937e-34
NC_018081.1\|WP_010738502.1\|508046_508787_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	5.84505e-20
NC_018081.1\|WP_002294578.1\|518976_519129_-\|50S-ribosomal-protein-L33	gnl\|CDD\|234783	PRK00504, rpmG, 50S ribosomal protein L33; Validated.	3.12722e-17
NC_018081.1\|WP_010720152.1\|515213_515882_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	gnl\|CDD\|224674	COG1760, SdaA, L-serine deaminase [Amino acid transport and metabolism].	3.8878e-76
NC_018081.1\|WP_010720158.1\|518787_518958_-\|preprotein-translocase-subunit-SecE	gnl\|CDD\|376355	pfam00584, SecE, SecE/Sec61-gamma subunits of protein translocation complex. SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.	4.32122e-12
NC_018081.1\|WP_010720157.1\|518142_518688_-\|transcription-termination/antitermination-protein-NusG	gnl\|CDD\|180161	PRK05609, nusG, transcription antitermination protein NusG; Validated.	4.49583e-84
NC_018081.1\|WP_010738508.1\|515895_516762_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl\|CDD\|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	7.31397e-101
NC_018081.1\|WP_010720150.1\|513459_514149_-\|50S-ribosomal-protein-L1	gnl\|CDD\|180071	PRK05424, rplA, 50S ribosomal protein L1; Validated.	1.55211e-146
NC_018081.1\|WP_010720148.1\|512156_512525_-\|50S-ribosomal-protein-L7/L12	gnl\|CDD\|234671	PRK00157, rplL, 50S ribosomal protein L7/L12; Reviewed.	9.48622e-45
NC_018081.1\|WP_010738510.1\|519289_519931_+\|CBS-domain-containing-protein	gnl\|CDD\|341358	cd02205, CBS_pair_SF, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains superfamily. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	1.48972e-13

>NC_018081.1|WP_010720149.1|512577_513081_-|50S-ribosomal-protein-L10
MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRKQLRDANVEMKVIKNSILSRAAKKAGLEGLDEVFTGPTAVAFSNEDVVAPAKIMDEFAKEAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVADKEDGDAA
>NC_018081.1|WP_010720148.1|512156_512525_-|50S-ribosomal-protein-L7/L12
MAMNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAAVAAGGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSKEEAEELKAKLEEVGASVTVK
>NC_018081.1|WP_010738507.1|510909_512055_+|site-specific-integrase
MAMIKQYQKKNGEKAWYFKTYLGIDPLTGKKRYTTKRGFKTQKEAKIALARLEVLATDKKLVKDNNYTFTQVKDMWIEQYKPTVRESTYLRVKFLFDKNISTFFGNKKIQSYNIAYCQEAINKWKEQYSTYKALKCYTSAVFDYAKKMNLIKENPMKEVTFSKGERKQKKTKLKYFEKEELQDFLECCQKDKFLITYPLFRVLAFTGIRKGEALALTWDDVDFFNKTLEINKTITRNSDNKFISTPPKTNTSIRKISLDDETLNILKAWKTQQKRYLLAHGQHAKTKNQIIFSSKNNNCIDITRPNIILSRICKEHNFNDITIHGFRHTHCSLLFETGLSIKEVQERLGHSDIHTTMNIYTHVTKKQKERSADKFAAYLNF
>NC_018081.1|WP_010738506.1|510582_510897_+|hypothetical-protein
MQYQEFKEWLENNSNSKHIFLTKWKDYQISKNSKRTGKTKKWDDDKIIRTGEEEWKKIVMNTYQKLKSHLGIPKYNGYQEWIDFIEKNEILESFDNSILEIELE
>NC_018081.1|WP_010738505.1|509399_510479_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKKALLSSVALLSLICASPVVYGETTSDSGPQKTTVSSVEKNSTTTSSTTPVKDSSTSSTTSSSTKDSTSSSSSAKTETSTTSKLETQNSTQASSSTTSRSTTKSSTSSSTESSSTTNSSTQETTQSSASPVTTLKATSKSYGVKPGVTISKNELLQLITYTNGDKNNLDVIITSNYAYISKNGQQNSKVYYTDLNALIGPANLNNIQVMTIAQALKLGFTPAQGNANKNIEVINCSLPGQYKITFRDRKTGLSTTTTVTVGNPASAVVSGNTQNSGTVNQTTMTTSSSTVATPKTNNATTKSPAPIATKSSVGTTKKNPVSTSKYTMPKTGEKVNHILSTAGVLMTLIVGSVALIWKF
>NC_018081.1|WP_010738504.1|509022_509259_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MKKVIFKKQPLKFLKKQDEKTKSRIIKAIYALPSGDVKPLQGHSSYKRLRVGTFRIIFDDDGKVCIIARIGNRGDIYK
>NC_018081.1|WP_010738503.1|508788_509022_+|hypothetical-protein
MTTKQEELSYAIKNLDDEATEIVLQLVYKLSNGNDLINEDGEVIVDDFYKKLLSSIDETDSGQDFTYEELKKELGIM
>NC_018081.1|WP_010738502.1|508046_508787_+|helix-turn-helix-transcriptional-regulator
MSETMAERIKRLRIEHNMTQEELGEKVGIKRAAINKYEKGNVENMKRSMIEKMSSIFGVSPVYLMALDDYSSSSIEKIYNQLSPPRQEKVYVFAKNQLDEQEKENSRNKNITSLEQYKQRKQQKKSMSVFYWCGAVSAGTGEFLADEYREEITLPTEIIPDDADFCLTVNGASMEPIFHDDDYVFVKRQLEVFSGAIGVVILNGQAFLKRIWFENDIARLQSFNSDYDDIIVTENDDFRIIGKVVM
>NC_018081.1|WP_010738501.1|507664_507883_-|hypothetical-protein
MNKEKLRSIIVLNGENQNVLSLFMGITPQSFSGKINERNGAEFTQSEIKLIKDRYNLTAEEVDEIFFSHFVS
>NC_018081.1|WP_010738250.1|507324_507609_-|hypothetical-protein
MQLNIPDEVIQNELASNITFIVLKEIEKRSSLLTKTVELPPYPNKSQVKEILRIGDDKLSGWISKGLKIQQWSEQDIRIERTELQRFLKETFEI
>NC_018081.1|WP_010720150.1|513459_514149_-|50S-ribosomal-protein-L1
MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEVAYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQKIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGKVTYRVDKAGNIHVPIGKVSFDNEKLVENFATIHDVLVKAKPSAAKGQYMKNITVTTTFGPGIHVDQASF
>NC_018081.1|WP_010720151.1|514252_514675_-|50S-ribosomal-protein-L11
MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNARTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIDKGSGEPNKTKVAKVSSDQVKEIAELKMEDLNAADIEAAMRMVEGTARSMGITVE
>NC_018081.1|WP_010720152.1|515213_515882_+|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta
MKELRYRSVFDIIGPVMIGPSSSHTAGAARIGKIVRSIFGEQPDSVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLQLAYEAGMEVLFVPKGEKAEHPNSVKLLLKKGKRKLSVTGISIGGGNIQISELNGFKISLSMGTPTFIIVHQDVPGMIAKVTNILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVDDTISKLTQLPKIDSVNYFD
>NC_018081.1|WP_010738508.1|515895_516762_+|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
MFFSIEELVRQAENYPSVAELMIAVEMDMSGRPREQIIAIMEKNLSVMEQSIAEGNEGVTSVTGITGGDAQKLARYLKEADFLSGETILSAVRNAIAVNEVNAKMGLICATPTAGSAGVVPGVLMAVRDRLSLTHEQQIEFLFTAGAFGLVIANNASISGAEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAIAITLKNMMGLICDPVAGLVEVPCVKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPAIFKETAEGGLAVTPTAKRLTEDILNR
>NC_018081.1|WP_010738509.1|517014_517899_-|alpha/beta-fold-hydrolase
MKNWRKSGIVGFLLMISVLFISGCQTKETSQSSEAAKTVETTQATKEKETQSTTPTLFFHGYSGTVNSFKGMIQRLESSESGKKELTLTVDVNGNVQAEGELSKEADNPMIQVLFVDNKNNEWNQTEWIKDCLSYLQQTYGINQVNLVGHSMGGVSGLRYLATYGQDQTLPKVDKFVAIAAPFNDFEENNGQSISDELANGPAIASSRYQDYQRLIGNVPTTTQILLIAGQVSETDLSDGTVPLSSALAVYALLKQHGNQVEEKVITGENVTHSMLHENKEVDALTRQFLWNMK
>NC_018081.1|WP_010720157.1|518142_518688_-|transcription-termination/antitermination-protein-NusG
MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVPEETEKEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPAPLLPEEVSHILRSIGMSLRQTDLEIEVGEVIKIIEGAFAGLEGQVTEVDEEKEKLKVNIDMFGRETSTELDFEQVDKID
>NC_018081.1|WP_010720158.1|518787_518958_-|preprotein-translocase-subunit-SecE
MKFIKSVKDEMKQVTWPSGKQLRKDTLVVIETSIIFGVMFFVMDTAIQSLFAYLLK
>NC_018081.1|WP_002294578.1|518976_519129_-|50S-ribosomal-protein-L33
MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYTLHKETK
>NC_018081.1|WP_010738510.1|519289_519931_+|CBS-domain-containing-protein
MLLKTLVYKKKDLTTVTETSTLEEALAILESSGYRCVPILDASGNIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKIFFTIKELPYIAVLDNDNHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLATIAKIIAKHSSIASCITLDIEKEEYIRRTLITLPAHTDQKVCDTIVNHLEKKNYKVIEIENLQNPE
>NC_018081.1|WP_010738511.1|520141_520645_-|QueT-transporter-family-protein
MQKTMERQRLMVVVVNGIIMALYLALTILVAPVSSGPIQFRISESLNHLVVFNRKLLWGVLGGVIVYNAFFGFGILDVVYGGGQTLISLGLTALLQNKVKNVKIRLALNTLFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIIMAISAPLMYYLDRSLDFEKRV

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Crispr_ID: NC_018081_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018081_2

1209433-1209598

TypeII

II-A,II-B

Consensus_repeat	Method
GTTTTAGAGCTATGTTGTTTTGAATGCTTCCAAAA	CRISPRCasFinder

2 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NC_018081_2

>merge|NC_018081|2|1209433-1209598|CRISPRCasFinder
GTTTTAGAGCTATGTTGTTTTGAATGCTTCCAAAACTTTCGCAAGCTCTAACCACTCGTCGTCGTTGTTTTAGAGCTATGTTGTTTTGAATGTTTCCAAAATGTAGAAGCGTTGTGCTTTACTCGATCGCTGTTTTAGTTTTGTGTTATTTTGAGTGCTGACCTCA

>NC_018081|2|2|1209433-1209598|CRISPRCasFinder
GTTTTAGAGCTATGTTGTTTTGAATGCTTCCAAAA	CTTTCGCAAGCTCTAACCACTCGTCGTCGTT
GTTTTAGAGCTATGTTGTTTTGAATGTTTCCAAAA	TGTAGAAGCGTTGTGCTTTACTCGATCGCT
GTTTTAGTTTTGTGTTATTTTGAGTGCTGACCTCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_018081.1\|WP_010737002.1\|1198523_1199657_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|176243
NC_018081.1\|WP_010720987.1\|1212814_1214647_+\|tyrosine-decarboxylase	unknown	unknown	gnl\|CDD\|163523
NC_018081.1\|WP_010720992.1\|1208323_1208668_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NC_018081.1\|WP_010720995.1\|1202666_1202795_-\|hypothetical-protein	unknown	unknown	unknown
NC_018081.1\|WP_010737001.1\|1197419_1197887_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326
NC_018081.1\|WP_010737006.1\|1210296_1210656_+\|DUF1622-domain-containing-protein	unknown	unknown	gnl\|CDD\|377914
NC_018081.1\|WP_010737011.1\|1220519_1221974_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|375760
NC_018081.1\|WP_010720993.1\|1207460_1208327_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NC_018081.1\|WP_014834429.1\|1198184_1198496_-\|YrhK-family-protein	unknown	unknown	gnl\|CDD\|372928
NC_018081.1\|WP_010720996.1\|1200918_1202613_-\|oleate-hydratase	unknown	unknown	gnl\|CDD\|237575
NC_018081.1\|WP_010737004.1\|1203468_1207479_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
NC_018081.1\|WP_010737009.1\|1216409_1217729_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NC_018081.1\|WP_010720990.1\|1209935_1210307_+\|DUF1622-domain-containing-protein	unknown	unknown	gnl\|CDD\|377914
NC_018081.1\|WP_010737005.1\|1208657_1209317_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NC_018081.1\|WP_010737012.1\|1222230_1222830_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|240029
NC_018081.1\|WP_010737008.1\|1214962_1216393_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|163525
NC_018081.1\|WP_010737014.1\|1223390_1223915_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_018081.1\|WP_010737015.1\|1223928_1224639_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225917
NC_018081.1\|WP_014834430.1\|1199945_1200791_+\|hypothetical-protein	unknown	unknown	unknown
NC_018081.1\|WP_010737010.1\|1217838_1220382_+\|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl\|CDD\|319775

Protein	Function_ID	Function_description	E-value
NC_018081.1\|WP_010737002.1\|1198523_1199657_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|176243	cd08283, FDH_like_1, Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1. Members identified as glutathione-dependent formaldehyde dehydrogenase(FDH), a member of the zinc-dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. MDH family uses NAD(H) as a cofactor in the interconversion of alcohols and aldehydes, or ketones. Like many zinc-dependent alcohol dehydrogenases (ADH) of the medium chain alcohol dehydrogenase/reductase family (MDR), these FDHs form dimers, with 4 zinc ions per dimer. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit.	3.95764e-174
NC_018081.1\|WP_010720987.1\|1212814_1214647_+\|tyrosine-decarboxylase	gnl\|CDD\|163523	TIGR03811, tyrosine_decarboxylase, tyrosine decarboxylase, Enterococcus type. This model represents tyrosine decarboxylases in the family of the Enterococcus faecalis enzyme Tdc. These enzymes often are encoded next to tyrosine/tyramine antiporter, together comprising a system in which tyrosine decarboxylation can protect against exposure to acid conditions. This clade differs from the archaeal tyrosine decarboxylases associated with methanofuran biosynthesis. [Cellular processes, Adaptations to atypical conditions].	0
NC_018081.1\|WP_010720992.1\|1208323_1208668_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	2.80036e-43
NC_018081.1\|WP_010737001.1\|1197419_1197887_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	8.51384e-07
NC_018081.1\|WP_010737011.1\|1220519_1221974_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|375760	pfam18333, ssDNA_DBD, Non-canonical single-stranded DNA-binding domain. This domain is found in ThermoDBP, a non-canonical single-stranded DNA-binding protein in Thermoproteales. Single-stranded DNA-binding proteins are needed for DNA metabolism, sequestering and protecting transiently formed ssDNA during DNA replication and recombination, detecting DNA damage and recruiting repair proteins. The outer edge of the ssDNA-binding cleft, formed by this domain, has a strongly positive electrostatic surface potential because of the conserved basic residues R49, K54, R65, R80, R86, R90, K97, and R112.	1.73679e-16
NC_018081.1\|WP_010720993.1\|1207460_1208327_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.61047e-122
NC_018081.1\|WP_014834429.1\|1198184_1198496_-\|YrhK-family-protein	gnl\|CDD\|372928	pfam14145, YrhK, YrhK-like protein. The YrhK-like protein family includes the B. subtilis YrhK protein, which is functionally uncharacterized. Its expression is under the control of the motility sigma factor sigma-D. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 60 amino acids in length.	1.82006e-14
NC_018081.1\|WP_010720996.1\|1200918_1202613_-\|oleate-hydratase	gnl\|CDD\|237575	PRK13977, PRK13977, myosin-cross-reactive antigen; Provisional.	0
NC_018081.1\|WP_010737004.1\|1203468_1207479_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	0
NC_018081.1\|WP_010737009.1\|1216409_1217729_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	3.1004e-124
NC_018081.1\|WP_010720990.1\|1209935_1210307_+\|DUF1622-domain-containing-protein	gnl\|CDD\|377914	pfam07784, DUF1622, Protein of unknown function (DUF1622). This is a family of 14 highly conserved sequences, from hypothetical proteins expressed by both bacterial and archaeal species.	4.39167e-21
NC_018081.1\|WP_010737005.1\|1208657_1209317_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	2.15998e-114
NC_018081.1\|WP_010737012.1\|1222230_1222830_+\|NUDIX-hydrolase	gnl\|CDD\|240029	cd04672, Nudix_Hydrolase_14, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	5.33139e-62
NC_018081.1\|WP_010737008.1\|1214962_1216393_+\|amino-acid-permease	gnl\|CDD\|163525	TIGR03813, put_Glu_GABA_T, putative glutamate/gamma-aminobutyrate antiporter. Members of this protein family are putative putative glutamate/gamma-aminobutyrate antiporters. Each member of the seed alignment is found adjacent to a glutamate decarboxylase, which converts glutamate (Glu) to gamma-aminobutyrate (GABA). However, the majority belong to genome contexts with a glutaminase (converts Gln to Glu) as well as the decarboxylase that converts Glu to GABA. The specificity of the transporter remains uncertain.	1.95886e-52
NC_018081.1\|WP_010737014.1\|1223390_1223915_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.66783e-18
NC_018081.1\|WP_010737015.1\|1223928_1224639_+\|hypothetical-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	9.23137e-71
NC_018081.1\|WP_010737006.1\|1210296_1210656_+\|DUF1622-domain-containing-protein	gnl\|CDD\|377914	pfam07784, DUF1622, Protein of unknown function (DUF1622). This is a family of 14 highly conserved sequences, from hypothetical proteins expressed by both bacterial and archaeal species.	5.7012e-21
NC_018081.1\|WP_010737010.1\|1217838_1220382_+\|HAD-IC-family-P-type-ATPase	gnl\|CDD\|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0

>NC_018081.1|WP_010737005.1|1208657_1209317_+|type-II-A-CRISPR-associated-protein-Csn2
MNLNFSLLEQPISFEKALIFVIEDVEVFSKVVHGVYQYGENSMLKFFNDKLQLLKPSELIVVTDILSFDSQAPTTLKLIYADLEQQLNENIELKSRIDQLTTKVQEWISEELLEHELDLVCEEMSMVELFKALKIRITTQPESIFQKIMEILQIYKYLVKKKCLVFINVGAYLTTTEMAELQEYISLCHMPVLFIEPGKIKGLKQTVLDQDYFLCEEMW
>NC_018081.1|WP_010720992.1|1208323_1208668_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMLLMFDLPTETSDDRKVYRRFRKFLLSEGFIMHQFSVYSKLLLNGTANQAMLGRLKAHHPKKGLVTLLTVTEKQFSRMVYLCGEKDLSPANSDERVIFLGEDVEDEP
>NC_018081.1|WP_010720993.1|1207460_1208327_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVINTHSKLTYANNHLVFKNAQQTEKIHLSEIDILILETTDITITTMLLKRLTDEKILVIFCDDKRLPSSQLFSYYGRHDSSLQLSKQIQWESDLKGVVWTTIIAQKIHNQCRFLQENDFVEKASALSKLSEELETFDPTNREGHAARIYFQTLFGNQFTREESNEINAGLDYGYTLLMSLFAREIVKNGCMTQFGLKHANQFNDFNLASDLMEPFRPLVDQIVYTYRDQPFPIIKRRLFDLFSQKYLYGKKEMFLTNIVTDYTNKTIKTLNNEGKGVPYFGI
>NC_018081.1|WP_010737004.1|1203468_1207479_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MTKDYTIGLDIGTNSVGWAVLTDDYQLMKRKMSVHGNTEKKKIKKNFWGARLFDEGQTAEFRRTKRTNRRRLARRKYRLSKLQDLFAEELCKQDDCFFVRLEESFLVPEEKQYKPASIFPTLEEEKEYYQKYPTIYHLRQKLVDSTEKEDLRLVYLALAHLLKYRGHFLFEGDLDTENTSIEESFRVFLEQYSKQSDQPLIVHQPVLTILTDKLSKTKKVEEILKYYPTEKINSFFAQCLKLIVGNQANFKRIFDLEAEVKLQFSKETYEEDLESLLEKIGDEYLDIFLQAKKVHDAILLSEIISSTVKHTKAKLSSGMVERYERHKADLAKFKQFVKENVPQKATVFFKDTTKNGYAGYIKGKTTQEEFYKFVKKELSGVVGSEPFLEKIDQETFLLKQRTYTNGVIPHQVHLIELKAIIDQQKQHYPFLEEAGPKIIALFKFRIPYYVGPLAKEQEASSFAWIERKTAEKINPWNFSEVVDIEKSAMRFIQRMTKQDTYLPTEKVLPKNSLLYQKYMIFNELTKVSYKDERGVKQYFSGDEKQQIFKQLFQKERGKITVKKLQNFLYTHYHIENAQIFGIEKAFNASYSTYHDFMKLAKTNQKAMQEWLEQPEMEPIFEDIVKILTIFEDRQMIKHQLSKYQEVFGEKLLKEFARKHYTGWGRFSAKLIHGIRDRKTNKTILDYLINDDDVPANRNRNLMQLINDEHLSFKEEIAKATVFSKHKSLVDVIQDLPGSPAIKKGIWQSLKIVEELIAIIGYKPKNIVIEMARENQKTHRTSPRLKALENGLKQIGSTLLKEQPTDNKALQKERLYLYYLQNGRDMYTGEPLEIENLHQYEVDHIIPRSFIVDNSIDNKVLVASKQNQKKRDDVPKKQIVNEQRIFWNQLKEAKLISPKKYAYLTKIELTPEDKARFIQRQLVETRQITKHVANILHQSFNQEEEGTDCDGVQIITLKATLTSQFRQTFGLYKVREINPHHHAHDAYLNGFIANVLLKRYPKLAPEFVYGKYVKYSLARENKATAKKEFYSNILKFLESDEPFCDENGEIYWEKSHHLPRIKKVLSSHQVNVVKKVEQQKGGFYKETVNSKEKPDKLIERKNNWDVTKYGGFGSPVIAYAIAFVYAKGKTQKKTRAIEGITIMEQAAFEKDPTTFLKEKGFPQVTEFIKLPKYTLFEFDNGRRRFLASHKESQKGNPFILSDQLVTLLYHAQHYDKITYQESFDYVNTHLSDFSAILTEVLAFAEKYTLADKNIERIQELYEENKYGETSMIAQSFLQLLQFNAIGAPADFKFFGVTIPRKRYTSLTEIWDATIIYQSVTGLYETRIRMGDLWAGEQ
>NC_018081.1|WP_010720995.1|1202666_1202795_-|hypothetical-protein
MSKKWIKLGIGLGILTLGAVYLGKKTGLLEDDRHLYDEFESI
>NC_018081.1|WP_010720996.1|1200918_1202613_-|oleate-hydratase
MRKSKAIMIGAGIANMAAAVYLIQEGNWRGDQITFYSLDDHGSNDGAPTDTVVDEYWNKNHPLENKKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTAAEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRLLLTKLIAMPDSEEEKLDNVTIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVNRTRYNQYESIMLPLINYLKDQGCQIILNRRVVDWEFKETPMQDEITVTGLKMINTLTNEEEHVVVDGDTGVLFTNGSITDSATLGDYDTPAVENMDYGAASSLWKKASERFYNLGNPDKFFADRDASEWVSFTLTTKDHLLLNEITRITTQVPGNALNSFISTTPITPLGQKDVNMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMTGKEMLEELIGQLSKVDPGPENIRTKETEIFDSVVNNIPVYMPYASALFNNRAKSDRPKVIPQHSTNLAFTGEFVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLMRAAKKMFE
>NC_018081.1|WP_014834430.1|1199945_1200791_+|hypothetical-protein
MVTFACSVTLFVIISVGIIQVTFFDQAYLLGQIEKTKYSELVLAEAAQNFRKENTEESEFSEVVATALSPRFVEEALRPFIQHTYEETNYELRDSNEVSEIIAQAVATVATKKQLTIDKEEKNKIETMIFIYMYHFQSALGDRYLTIFIENIVSARKIVVPLFYICLGLLAFWLVYLYRLINKTPFSFLRYGMFILGTTGSMFCVLAGLLYIQDVLHNIAFHSQATLQLMTHYVQDLLLYPAIIGGILLFCAVLFGGGSKLLQKRQNKKWLKTGSSTLKKA
>NC_018081.1|WP_010737002.1|1198523_1199657_-|alcohol-dehydrogenase-catalytic-domain-containing-protein
MKAVTWQGNQKMEIRNVDDPKIVEPTDAIIRITATAICGSDLHLYHHGEAVLEKGYVVGHEPMGIVEEVGPAVKKLKKGQRVVIPFNISCGHCHFCTHEMESQCDRSNPDQLYGGLFGFGRLNGNHWGGQAEYLRVPFADSTSFIVPDNDLADEKVLFLSDILPTAYWSVQNANVKKGDTVVVLGSGPVGLFAQKFAAMAGAERVIAVDPVQHRIDKAARYNHVETYLLEDTQSAGKELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGTISPIQMAAQAVKKFGTVQITGVYMTPASSYPLQEFFMRDITVKHGQAPIVHLMPKIYEMIAAGLFDPTQIITHAMPLADAARAYEIFDKKEDKNIKVVLKP
>NC_018081.1|WP_014834429.1|1198184_1198496_-|YrhK-family-protein
MPEIKRKSHEIDIGKEEDIEIAGQRFRLYFQNRYTLLSLAVDLLTGIFYIFGSVALLTDIPDRYSTYCYLVGAIFLTARPILKIVRNVFIYDEKKNKKERKKE
>NC_018081.1|WP_010737001.1|1197419_1197887_+|GNAT-family-N-acetyltransferase
MKGYELVKIRERPEWLEQAAQWFTSKWHLPLSFYQESMEDSLQSSNAVPQWYIVVTSEQKIIAGAGVIANDFHDRPDLTPNVCALFVEKEYRNQGIAKEILSFIRKDMGALGISQLYVATDHTGFYERYEWEYLTTVQDNEGIPVYLYQLAIFTT
>NC_018081.1|WP_010720990.1|1209935_1210307_+|DUF1622-domain-containing-protein
MFDTNLITYLDWLIAILNIASIIILLVGIFLVLKNLFDWHPLKKDYEQRNFRNAEVRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLAVIIIIRTIISYFLNLETQDKKQVKVGTHNGN
>NC_018081.1|WP_010737006.1|1210296_1210656_+|DUF1622-domain-containing-protein
MEINLIEKLAPYLEQLVIILDVFAILIILWGAWLAIKDFLYFSFTERRIKAERINQNNAIKKMLGGYILLSLEVLISAGIIESIIKPTLEDVFQLAALVVIRTIISFFLNKEIGSDARQ
>NC_018081.1|WP_010720987.1|1212814_1214647_+|tyrosine-decarboxylase
MKDMDIKAVFIGDKSENGAFYKMQLNKMVDEHLGWRENYLPGDVAAISEADKQAPRYIATREHMVEVLDEVSQRMRAGSIPWHSAGRYWGQMNAETLMPALLAYNFAMLWNPNNVALESSMATSQMEAEVGQDFADLFNMTGGWGHITADGSIANLEGLWYARCIKSIPLAVKEVYPEKVKDKTDWELLNLSVEEILEMVGTFSDEELDAVKAASSRSGKHLQELGKWLVPQTKHYSWMKALDICGIGLDQMIAIPVQEDYRMDVAILEKTIRELAAQKIPVLGVVAVVGTTEEGQVDSVDKIVELREKLYKEGIYFYLHVDAAYGGYARALFLNEAGEFVPYESLPDFFEEHHVFNYDVSIDQSVYDGFKAISEADSVTIDPHKMGYVPYAAGGIVIKHKEMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLPLNITGYGQLIGASIEAAQRFRAFLEQLSFTIKGKTIEVYPLNHPDFNMVNWVFKVKGCTDLKTINELNEKMFNRSSYMEGDVYSEHFITSHTTFMKEEYGDSPLPFIERIGLSKEEWQKEQKVTLLRAAIMTPYLNDDKIFEFYTQGITKAMEKTLNEIL
>NC_018081.1|WP_010737008.1|1214962_1216393_+|amino-acid-permease
MTDSKTSQITTLTFIGMTCALVASVRNIPDVAATGWTMLFYMLVAVLFYAFPISLISGEFAGMFPQKGGPELWVSNSLGRKWGFVVSWLLWVQMFPGMVMVASALAPLLGNMIDNVPLGLNSKFTLIVILVVYWIITLLNLKFDMAKIGGKIGVWLGLYIPLAIMLLLGIFSWIKVGIQPHATLGHFSWAKLIPDAETAKSFVYFAPIMFIFTGIEMSSVYITRLKNPVKTYTKGIFAALIFLFFVNTLNALVVANVVPKGQMELNNIAQSISIYCQILGLPHIIVNIFSLLVFVGVAVQLSAWASGPAKTVTASARKGAYPPKFNFWKTNQFDVSKSVILTQSTIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAILKLRKAKPELARPFRIGKKGGKGDLGAWIVVLVLFAAIGCSVGLTMQAGTLINFFAVTVISLILFIAPLCIDKIRKPSWEQEVQQKLNQE
>NC_018081.1|WP_010737009.1|1216409_1217729_+|amino-acid-permease
MERTTMKKTLTNRNIQMIALGGAIGTGLFLGSAKAIKLAGPAVLLTYFVCGLAIYGLMYAMGELFLSNNEFQSIGDFIQYYLGERWAFLVNWTYWLCWMGAGLTELTAIGLYIRFWLPALSPLISGIFALIALVIINVVAVRWFGELESLFSTIKIFGILLFILLGIGVCFLYFKSPRIGVRENFDQLQTIFPFGLTGLVAAFPMVLFSFAGVEMIGLTVGETADPQKNLKKAIQCLPARILFFYIGTIVAILLVVPWQSLDLKESPLVTMLQFIHCSKGAGVINLIILVASLSSTNSAIYSTSRILYNTAKEKNLSKWFLTLSSRGVPLHGILFTGGMFLLGLCLHFFVSDSRILFQLLAGMTTISFLFVWSAILFAHLKLTKSQLKKWKDRLILCFFGLVGISLFFEPTTRVIPVVSVVWFGALNLIYQRIRQTSPK
>NC_018081.1|WP_010737010.1|1217838_1220382_+|HAD-IC-family-P-type-ATPase
MVWYKETAQEVMKTLKTTPDGLNQDERISRLKENGYNHIEVKKKVSPLRKFLKHLTELLMIILLVASLLKFFTGEVIEGSIILAVVLVNSFVGYWQERKAEEALNGLEKLLGQNAVIFTEGIKELVPAKELVPGDLLALKAGDVIPADVRLIEVHDFMVEEAALTGESEAVEKTSERLTTTVSTGDQKNLAFSGTLVQTGTAIGVVIETGDTTEIGKINQALQSVQQQTTPLVKKINQLNKQIFRGILFLSLFLLFFTTFRYGLEMNFLFSTIIALIVSMIPEGLPAVLTMILSLGVNEMAKEQAIIKGLPSVETLGSMTVICSDKTGTLTKNEMSVVETVTDQEETMLAIMKNCQEIQTKANQNVTELTGNPTELALLRYTAKASLPLEPVKGKIPFSSSYKYMATMHDKQEHAIVYVKGAPEVLLAKANLTPKQVGKWQEEAMKLAQKGQRVLGFAYKTLAPDQELGHDQLNELTFVGIAGIIDPPKESAIRAVKECQNAGISVKMITGDHKDTAQAIAEQIGLKHTKNVLEGIDIDRLSDEELAKQVKSVDVFARTTPEHKLRIVDALQKNEEIVGMTGDGVNDAPALKRADVGIAMGIKGSEVSKQAADRVLGDDNFHTIAKAVKEGRRILDNLQKTINFFLPTALAQGLVIIWALLVNQPLPLTPVQILWVNMVTTITLSYALGFEKAGKDTMSRSPRDPKQGILTRYSVFRIFYVSLLIMIPAYLLAMSFEGQALQQTMLLQNIVAAQAVYMINCRELLDPSLNRSLFENKALFLSLGMLVLLQAGVIYLPIAQQLIGTTSLSLTEQLPILLNILILFVIVEIEKRISKMIAKKRNAELPT
>NC_018081.1|WP_010737011.1|1220519_1221974_-|helix-turn-helix-domain-containing-protein
MYSLMKKIITEKDIKRQVSLVELLLNHSQITVNELAEVVNTTERTIFSDLQTIKTQLPKGWLINSDQSGIQLKNEQNLLTNELWEIFLTQSISVQLLKELLTIKEVATPTFLARNGLSYETLNRHVKKLNQQLVVYELQIEQNRHRLSFSGEEETIRLFYHRLLMPFTHNNYFFEDYSIHESHYFRFLKRLRQAELAVDTEEVFGICWFFINTIRIKAGCRIPTSLFSTQDQLFLLYAPELEKLYRTEGVYLKDKEAAFAFSCFLDSWNYNNSYPPMILDILHRHPAETNIREFVNRLSESLAIKELEQTNLPENLILLLLKYYESPLLIEQTTKQYHYYLKEYEQEYPELYPHKFALLQQVKESTSMVKKVTNETYFFYLLSLLIQQTLLAVQPYQATIYFIFQGEPSWKAFLQQELNAYLGKRVILEPIELSQLSDITIKKNDLLVSNIPIDTPPMPVIYLSTIPTKNELDRLSDLSLRSYL
>NC_018081.1|WP_010737012.1|1222230_1222830_+|NUDIX-hydrolase
MENRLNDYRRLLAIAQAGLLYGKDVFDKERYEELQEISLKLLSEVGLETKEEWTSLIEAHEGYPTPKVDVRAWIKQDEKILLIEDTKTQEWSLPGGFAEVGLSPKENIRKEVKEETGLEVEVGQLLAIFDTNLRTDIPQAFQYYKIVFSCAILSGTFVANHETSNMKFFHLNDLPKLSLKRTTKEQLLILEKATLPYCD
>NC_018081.1|WP_010737014.1|1223390_1223915_+|GNAT-family-N-acetyltransferase
MKTIEIVGIKETEVEKLQAISIETYQATFGEHNSEELMTTYLDEAYALDKLRRELQEEQSEFYWAVLDDRIAGYLKLNIGQAQTEAMGEGFLEIERIYVRSPFKSKGIGSRLIEFAVQKAQEKQKEAIWLGVWEHNYPALAFYRKHGFQHHSQHIFYMGDDAQTDYLYVKNLQK
>NC_018081.1|WP_010737015.1|1223928_1224639_+|hypothetical-protein
MEKIIAEQNFWEVFPEATIEVLVVEGIDNHVDKAKEEQFHQLLNDAAKEARGYLTEETFSQNEVIAQWRQAFSRFKTKKGARSSIEALLKRASQEREFFPINPLVDIYNSISLTFGVPCGGEDQEKIKGDLHLGKAHGGESFLPLGAEADAPALPEEIIYYDNEGAICRSFNWREAQRTMLTEDTTKAILVIESVTKEQASRGAKAMTELKKRVEQTFGVEGKTFTLTKEHPEMNI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_018081_2	2.1\|1209468\|31\|NC_018081\|CRISPRCasFinder	1209468-1209498	31	HG796332	Uncultured bacterium plasmid pRGI00484	2500-2530	9	0.71
NC_018081_2	2.1\|1209468\|31\|NC_018081\|CRISPRCasFinder	1209468-1209498	31	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	819082-819112	9	0.71

1. spacer 2.1|1209468|31|NC_018081|CRISPRCasFinder matches to HG796332 (Uncultured bacterium plasmid pRGI00484) position: , mismatch: 9, identity: 0.71

ctttcgcaagctctaaccactcgtcgtcgtt	CRISPR spacer
ctttcgcaagatttaaccactcgttaatcaa	Protospacer
********** *.***********.. .

2. spacer 2.1|1209468|31|NC_018081|CRISPRCasFinder matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 9, identity: 0.71

ctttcgcaagctctaaccactcgtcgtcgtt	CRISPR spacer
gctcgacaagctctacccactcgacgtcgac	Protospacer
 .*. .********* ******* ***** .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

66364 : 155215

100

Enterococcus_phage(26.47%)

capsid,tail,terminase,tRNA,protease,integrase,head,portal,plate

attL 67389:67404|attR 155586:155601

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010738196.1\|66364_69157_-\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	6.2e-90	27.4
67389:67404	attL	NA	NA	NA	NA
WP_010719771.1\|69415_70120_-	DivIVA domain-containing protein	NA	NA	NA	NA
WP_034686156.1\|70957_71227_-	YggT family protein	NA	NA	NA	NA
WP_010719773.1\|71256_71853_-	cell division protein SepF	NA	NA	NA	NA
WP_010719774.1\|71852_72539_-	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_010719775.1\|72553_73798_-	cell division protein FtsZ	NA	NA	NA	NA
WP_010719776.1\|73820_75149_-	cell division protein FtsA	NA	NA	NA	NA
WP_010738199.1\|76566_77649_-	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	NA	NA	NA	NA
WP_010738200.1\|77665_79036_-	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	NA	NA	NA	NA
WP_010719780.1\|79049_80012_-	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
WP_010738201.1\|80038_82231_-	penicillin-binding protein	NA	NA	NA	NA
WP_010719782.1\|82231_82627_-	cell division protein FtsL	NA	NA	NA	NA
WP_010738202.1\|82631_83591_-	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA	NA	NA	NA
WP_010719784.1\|83611_84097_-	division/cell wall cluster transcriptional repressor MraZ	NA	NA	NA	NA
WP_010719785.1\|84214_84583_-	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_010738203.1\|84838_85795_+	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_010719787.1\|85864_85981_+	DUF4044 domain-containing protein	NA	NA	NA	NA
WP_010719788.1\|86203_87883_-	DNA repair protein RecN	NA	NA	NA	NA
WP_010719789.1\|87900_88350_-	arginine repressor	NA	NA	NA	NA
WP_010738204.1\|88449_89268_-	TlyA family RNA methyltransferase	NA	NA	NA	NA
WP_010719791.1\|89282_90167_-	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_010719792.1\|90166_90391_-	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_010738205.1\|90396_91737_-	exodeoxyribonuclease VII large subunit	A0A160DF99	Gordonia_phage	7.2e-28	33.0
WP_010738206.1\|91737_92583_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	8.8e-40	38.9
WP_010719795.1\|92677_93127_-	transcription antitermination factor NusB	NA	NA	NA	NA
WP_010719796.1\|93119_93545_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_010719797.1\|93780_94845_-	aminopeptidase P family protein	NA	NA	NA	NA
WP_010719798.1\|95034_95280_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_010719799.1\|95452_95827_-	DUF956 family protein	NA	NA	NA	NA
WP_010738207.1\|95943_96858_-	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_010719801.1\|96879_97683_-	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
WP_010719802.1\|97715_98705_-	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
WP_010738208.1\|98803_99295_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_010719804.1\|99489_102315_-	sigma-54-dependent transcriptional regulator	NA	NA	NA	NA
WP_014834192.1\|102756_103866_-	acyltransferase family protein	NA	NA	NA	NA
WP_010738465.1\|105132_105312_+	hypothetical protein	NA	NA	NA	NA
WP_014834193.1\|105326_105884_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_010718754.1\|106006_106204_-	cold-shock protein	Q9AZD3	Lactococcus_phage	1.7e-23	78.5
WP_010718753.1\|106548_106698_-	hypothetical protein	NA	NA	NA	NA
WP_080593137.1\|107265_107781_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_010738212.1\|107782_110521_-	N-6 DNA methylase	A0A2H4JBT5	uncultured_Caudovirales_phage	5.7e-80	34.4
WP_010738213.1\|110877_111915_-	hypothetical protein	A0A0M4S679	Enterococcus_phage	3.6e-51	61.4
WP_010738214.1\|111911_112202_-	hypothetical protein	NA	NA	NA	NA
WP_010738215.1\|112194_112545_-	hypothetical protein	A0A0P0IZF9	Lactobacillus_phage	1.0e-13	39.4
WP_010738216.1\|112597_115030_-\|plate	BppU family phage baseplate upper protein	A0A2H4J709	uncultured_Caudovirales_phage	1.2e-28	25.0
WP_010738217.1\|115029_116079_-	hypothetical protein	A0A0B5D0C2	Listeria_phage	1.1e-23	28.7
WP_010738218.1\|116078_117119_-\|tail	phage tail protein	Q9T1A5	Listeria_phage	7.4e-97	52.8
WP_010738219.1\|117127_117949_-\|tail	phage tail family protein	Q9T1A6	Listeria_phage	3.8e-56	44.2
WP_010738220.1\|117952_124438_-\|tail	phage tail tape measure protein	A0A0M5M3L4	Enterococcus_phage	4.9e-122	52.7
WP_010738221.1\|124631_124952_-	hypothetical protein	NA	NA	NA	NA
WP_010738222.1\|125190_125775_-\|tail	phage tail protein	A0A2P0ZLF5	Lactobacillus_phage	2.6e-35	44.6
WP_014834199.1\|126634_126985_-	hypothetical protein	A8ATA1	Listeria_phage	1.7e-29	57.1
WP_010738226.1\|126971_127334_-\|head,tail	phage head-tail connector protein	NA	NA	NA	NA
WP_143139787.1\|127380_127491_-	hypothetical protein	NA	NA	NA	NA
WP_010738227.1\|127577_128717_-\|capsid	phage capsid protein	A0A0C5AEH1	Paenibacillus_phage	1.3e-118	58.2
WP_014834201.1\|128775_129444_-\|protease	Clp protease ClpP	A0A0B5A796	Paenibacillus_phage	1.0e-67	60.7
WP_010738229.1\|129478_130714_-\|portal	phage portal protein	A0A0U3SQF0	Bacillus_phage	2.2e-116	53.9
WP_010738230.1\|130717_132505_-\|terminase	terminase large subunit	A0A1B1P7R3	Bacillus_phage	1.0e-194	54.9
WP_010719498.1\|132495_133017_-\|terminase	phage terminase small subunit P27 family	NA	NA	NA	NA
WP_014834202.1\|133345_133660_-	HNH endonuclease	A0A2H4JI70	uncultured_Caudovirales_phage	4.0e-14	44.4
WP_010738231.1\|133819_133960_-	hypothetical protein	NA	NA	NA	NA
WP_010718385.1\|133946_134255_-	hypothetical protein	NA	NA	NA	NA
WP_010737830.1\|134584_134887_+	hypothetical protein	NA	NA	NA	NA
WP_010738232.1\|136118_136532_-	autolysin	D2IYV6	Enterococcus_phage	4.3e-56	82.5
WP_010738234.1\|137156_137849_-	phage regulatory protein	R9QMT9	Lactococcus_phage	1.2e-23	39.6
WP_010738235.1\|138029_138407_-	hypothetical protein	D2IYU9	Enterococcus_phage	5.0e-11	35.8
WP_010738236.1\|138403_138952_-	DUF1642 domain-containing protein	A0A0E3T929	Enterococcus_phage	1.0e-41	50.5
WP_010738237.1\|138951_139338_-	hypothetical protein	A0A060ABA9	Staphylococcus_phage	3.9e-11	32.1
WP_014834205.1\|139349_139736_-	hypothetical protein	A0A1S5SA89	Streptococcus_phage	2.9e-46	72.9
WP_014834206.1\|139732_140044_-	hypothetical protein	NA	NA	NA	NA
WP_010738238.1\|140276_140690_-	hypothetical protein	NA	NA	NA	NA
WP_010738239.1\|140686_140947_-	hypothetical protein	NA	NA	NA	NA
WP_010738240.1\|140964_141159_-	hypothetical protein	NA	NA	NA	NA
WP_014834207.1\|141159_142011_-	ATP-binding protein	A0A0U4K4W7	Exiguobacterium_phage	1.8e-16	28.0
WP_010738242.1\|142824_143760_-	recombinase RecT	D2IYT9	Enterococcus_phage	4.0e-94	56.6
WP_010738243.1\|143761_144703_-	YqaJ viral recombinase family protein	D2IZK1	Enterococcus_phage	4.7e-127	70.6
WP_014834210.1\|144790_144940_-	hypothetical protein	NA	NA	NA	NA
WP_010738245.1\|144936_145230_-	hypothetical protein	NA	NA	NA	NA
WP_010738246.1\|145302_145455_-	hypothetical protein	F0PIH3	Enterococcus_phage	4.9e-10	65.3
WP_010738247.1\|145451_145640_-	hypothetical protein	NA	NA	NA	NA
WP_010738248.1\|145718_145931_+	hypothetical protein	NA	NA	NA	NA
WP_010738249.1\|145931_146078_-	hypothetical protein	NA	NA	NA	NA
WP_010738250.1\|146226_146511_-	hypothetical protein	NA	NA	NA	NA
WP_025480544.1\|146613_147102_+	DUF2321 domain-containing protein	Q6SEF3	Lactobacillus_prophage	3.4e-28	41.8
WP_010738251.1\|147323_147674_+	hypothetical protein	NA	NA	NA	NA
WP_010738252.1\|147663_147882_-	DUF2829 domain-containing protein	Q8SDS1	Staphylococcus_virus	2.5e-07	43.5
WP_010738253.1\|147971_148367_+	hypothetical protein	NA	NA	NA	NA
WP_010738254.1\|148471_148693_-	hypothetical protein	NA	NA	NA	NA
WP_010738255.1\|148794_149079_+	hypothetical protein	NA	NA	NA	NA
WP_010738256.1\|149068_149281_-	hypothetical protein	NA	NA	NA	NA
WP_010738257.1\|149294_149495_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_010738258.1\|149763_150177_+	helix-turn-helix transcriptional regulator	Q5YAA4	Bacillus_phage	1.3e-31	51.4
WP_010738259.1\|150189_150642_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_010738260.1\|150716_151685_+	3'-5' exoribonuclease	NA	NA	NA	NA
WP_010738261.1\|151688_152234_+	hypothetical protein	NA	NA	NA	NA
WP_010738262.1\|152395_152935_+	DUF4352 domain-containing protein	A0A0P0IXE0	Lactobacillus_phage	4.4e-37	62.7
WP_010738263.1\|152996_153311_+	hypothetical protein	NA	NA	NA	NA
WP_010738264.1\|153323_154472_+\|integrase	site-specific integrase	A0A1S5S7K9	Streptococcus_phage	2.3e-67	40.4
WP_010719806.1\|154564_154858_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_010738265.1\|154870_155215_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
155586:155601	attR	NA	NA	NA	NA

DBSCAN-SWA_2

422269 : 506150

Bacillus_phage(26.32%)

capsid,terminase,tail,protease,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010738437.1\|422269_422941_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_010738439.1\|425127_425607_-	hypothetical protein	NA	NA	NA	NA
WP_010720049.1\|425848_426658_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	2.2e-32	33.5
WP_010720051.1\|427580_428894_-	hypothetical protein	NA	NA	NA	NA
WP_010738440.1\|428890_430726_-	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	2.6e-36	37.9
WP_010720053.1\|430729_431434_-	response regulator transcription factor	W8CYM9	Bacillus_phage	4.4e-45	42.0
WP_010738441.1\|431676_432366_-	hypothetical protein	NA	NA	NA	NA
WP_014834279.1\|432809_434222_-	DegV family EDD domain-containing protein	A0A1X9I5J4	Streptococcus_phage	4.2e-10	22.5
WP_010738443.1\|434536_435481_+	hypothetical protein	NA	NA	NA	NA
WP_010738444.1\|436220_436820_+	SOS response-associated peptidase family protein	NA	NA	NA	NA
WP_010720060.1\|437088_438816_-	ABC transporter permease/substrate binding protein	NA	NA	NA	NA
WP_010720061.1\|438808_440002_-	glycine betaine/L-proline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.5e-29	37.0
WP_010720062.1\|440200_440833_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_010738445.1\|441025_441148_-	hypothetical protein	NA	NA	NA	NA
WP_010738446.1\|441148_443284_-	ferrous iron transport protein B	NA	NA	NA	NA
WP_010720065.1\|443287_443788_-	ferrous iron transport protein A	NA	NA	NA	NA
WP_010738447.1\|444196_444421_+	glutaredoxin-like protein NrdH	A0A0M7REK7	Lactobacillus_phage	3.0e-11	41.3
WP_010720067.1\|444567_446727_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	7.0e-267	63.7
WP_010738448.1\|446783_447752_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	1.6e-125	69.8
WP_010720069.1\|447847_448552_-	SIS domain-containing protein	NA	NA	NA	NA
WP_010738449.1\|448596_449391_-	PTS system mannose/fructose/sorbose family transporter subunit IID	NA	NA	NA	NA
WP_010720071.1\|449374_450184_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_010720072.1\|450193_451153_-	PTS mannose/fructose/sorbose transporter subunit IIAB	NA	NA	NA	NA
WP_010738450.1\|451149_452466_-	alpha-L-fucosidase	NA	NA	NA	NA
WP_010738451.1\|452654_453539_+	hypothetical protein	NA	NA	NA	NA
WP_010738452.1\|453605_454112_+	hypothetical protein	NA	NA	NA	NA
WP_010738453.1\|454098_455880_+	L-fucose isomerase	NA	NA	NA	NA
WP_034686205.1\|455898_456540_+	L-fuculose-phosphate aldolase	NA	NA	NA	NA
WP_010720077.1\|456594_457353_+	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_010720078.1\|457549_458266_-	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_010720079.1\|458336_459434_-	PTS fructose transporter subunit IIC	NA	NA	NA	NA
WP_010720080.1\|459452_459776_-	PTS fructose transporter subunit IIB	NA	NA	NA	NA
WP_010720081.1\|459797_460250_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_010720082.1\|460269_460581_-	PTS fructose transporter subunit IIB	NA	NA	NA	NA
WP_010738455.1\|460577_461018_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_010720084.1\|461007_462492_-	PRD domain-containing protein	NA	NA	NA	NA
WP_010738456.1\|462980_464120_-	AI-2E family transporter	NA	NA	NA	NA
WP_010738457.1\|464438_465152_-	MgtC/SapB family protein	G3MA03	Bacillus_virus	9.4e-19	43.7
WP_010738458.1\|465297_465999_-	glucosamine-6-phosphate deaminase	NA	NA	NA	NA
WP_010738459.1\|466428_467958_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	2.7e-47	27.9
WP_071859326.1\|468299_468602_-	type II toxin-antitoxin system PemK/MazF family toxin	A0A1S5SAB3	Streptococcus_phage	2.3e-14	45.9
WP_010738460.1\|468626_468860_-	hypothetical protein	NA	NA	NA	NA
WP_010738461.1\|469260_470448_-	MFS transporter	NA	NA	NA	NA
WP_010720092.1\|470624_471302_-	TVP38/TMEM64 family protein	NA	NA	NA	NA
WP_010738462.1\|471693_472068_-	hypothetical protein	NA	NA	NA	NA
WP_010738464.1\|472456_472672_-	hypothetical protein	NA	NA	NA	NA
WP_014834283.1\|475380_476409_-	Abi family protein	A0A0H4U080	Erysipelothrix_phage	1.6e-30	34.1
WP_014834286.1\|477941_478196_-	hypothetical protein	NA	NA	NA	NA
WP_014834287.1\|478188_478539_-	hypothetical protein	A0A0P0IZF9	Lactobacillus_phage	5.8e-14	40.4
WP_010738470.1\|478597_480568_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_010738471.1\|480554_481952_-\|tail	phage tail protein	A0A1S5SAP8	Streptococcus_phage	1.0e-45	30.5
WP_010738472.1\|481954_482689_-\|tail	phage tail family protein	A0A1B2APY0	Phage_Wrath	1.6e-45	40.7
WP_010738473.1\|482672_486737_-	tape measure protein	A7J2A5	Streptococcus_phage	3.4e-65	52.3
WP_010738474.1\|486729_487311_-	bacteriophage Gp15 family protein	Q5YA62	Bacillus_phage	3.5e-40	52.3
WP_010738475.1\|487319_487757_-	hypothetical protein	A0A141DZI4	Streptococcus_phage	9.5e-14	37.1
WP_010738476.1\|487842_488319_-	hypothetical protein	Q5YA64	Bacillus_phage	2.1e-46	62.7
WP_010738477.1\|488311_488719_-\|capsid	minor capsid protein	Q5YA65	Bacillus_phage	1.3e-36	53.4
WP_010738478.1\|488718_489066_-\|capsid	minor capsid protein	A0A141DZI7	Streptococcus_phage	8.1e-24	44.7
WP_010738479.1\|489066_489408_-\|capsid	minor capsid protein	Q5YA67	Bacillus_phage	8.2e-37	63.7
WP_010738480.1\|489401_489818_-	hypothetical protein	Q5YA68	Bacillus_phage	1.8e-30	54.9
WP_010738481.1\|489814_490753_-	hypothetical protein	NA	NA	NA	NA
WP_010738482.1\|490823_491684_-	hypothetical protein	U3PDP8	Lactobacillus_phage	1.6e-97	61.7
WP_010738483.1\|491686_492256_-	phage scaffolding protein	X2CYF9	Lactobacillus_phage	2.0e-11	29.4
WP_010738484.1\|492358_493522_-\|capsid	phage minor capsid protein	Q5YA73	Bacillus_phage	3.1e-136	60.8
WP_010738485.1\|493521_495003_-\|portal	phage portal protein	Q5YA75	Bacillus_phage	1.8e-157	55.6
WP_010738486.1\|495062_496403_-\|terminase	PBSX family phage terminase large subunit	Q5YA76	Bacillus_phage	5.4e-185	69.4
WP_010738487.1\|496389_497049_-	helix-turn-helix domain-containing protein	D7RWI2	Brochothrix_phage	1.2e-41	43.8
WP_010738488.1\|498216_498696_-	hypothetical protein	A0A2H4JFW6	uncultured_Caudovirales_phage	4.1e-26	46.0
WP_014834289.1\|498658_499249_-	hypothetical protein	A6MAI4	Lactococcus_virus	5.7e-38	77.8
WP_010738490.1\|499245_499761_-	DUF1642 domain-containing protein	A0A0E3T929	Enterococcus_phage	6.6e-30	54.9
WP_010719512.1\|499757_500159_-	hypothetical protein	D2IZL0	Enterococcus_phage	3.6e-36	62.4
WP_042969823.1\|500170_500545_-	hypothetical protein	A0A1S5SA89	Streptococcus_phage	1.2e-44	75.4
WP_010738491.1\|500860_501097_-	hypothetical protein	NA	NA	NA	NA
WP_010738492.1\|501121_501481_-	DUF1064 domain-containing protein	A0A1P8BKR1	Lactococcus_phage	1.8e-18	48.2
WP_014834293.1\|501477_502329_-	ATP-binding protein	A0A0U4K4W7	Exiguobacterium_phage	1.2e-15	28.0
WP_014834294.1\|502343_503102_-	DnaD domain protein	F0PII1	Enterococcus_phage	1.6e-29	61.4
WP_010738494.1\|505253_505595_-	hypothetical protein	NA	NA	NA	NA
WP_010738495.1\|505587_505911_-	hypothetical protein	NA	NA	NA	NA
WP_010738496.1\|505958_506150_-	helix-turn-helix transcriptional regulator	J9QEC3	Clostridium_phage	2.9e-07	56.5

DBSCAN-SWA_3

1586014 : 1593612

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010738042.1\|1586014_1587763_+	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	9.3e-52	41.9
WP_010718691.1\|1587786_1588098_+	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_010718690.1\|1588121_1588718_+	recombination protein RecR	NA	NA	NA	NA
WP_010718689.1\|1588781_1589426_+	dTMP kinase	M1PSC7	Streptococcus_phage	3.5e-57	52.2
WP_010718688.1\|1589440_1589770_+	cyclic-di-AMP receptor	NA	NA	NA	NA
WP_010718687.1\|1589778_1590720_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	3.4e-32	32.3
WP_010738041.1\|1590755_1591580_+	stage 0 sporulation family protein	NA	NA	NA	NA
WP_010718685.1\|1591572_1591917_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	2.9e-18	41.4
WP_010718684.1\|1592339_1593206_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	8.6e-91	63.0
WP_002328071.1\|1593351_1593612_+	hypothetical protein	A0A0S2MYI8	Enterococcus_phage	6.9e-12	52.6

DBSCAN-SWA_4

1816862 : 1925033

123

Enterococcus_phage(36.54%)

capsid,terminase,tail,tRNA,transposase,protease,integrase,head,portal,holin,plate

attL 1879173:1879196|attR 1914457:1914480

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025480115.1\|1816862_1817612_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_002286913.1\|1817749_1818097_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_010737911.1\|1818658_1820005_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_010718458.1\|1820152_1820866_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_010737910.1\|1821060_1822479_+	glycoside hydrolase family 1 protein	NA	NA	NA	NA
WP_010737909.1\|1823323_1823551_+	ATP-binding protein	NA	NA	NA	NA
WP_010737908.1\|1823576_1824263_+	response regulator transcription factor	Q56AR1	Bacillus_thuringiensis_phage	4.4e-05	31.6
WP_010737907.1\|1824444_1825080_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_010737903.1\|1827705_1828065_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_010737902.1\|1828302_1829442_-	PLP-dependent transferase	NA	NA	NA	NA
WP_010737901.1\|1829708_1830062_+	reactive intermediate/imine deaminase	NA	NA	NA	NA
WP_010737900.1\|1830079_1831408_+	CoA-disulfide reductase	NA	NA	NA	NA
WP_010737899.1\|1831422_1832841_+	cation:dicarboxylase symporter family transporter	NA	NA	NA	NA
WP_010737898.1\|1833096_1833762_-	PAS domain-containing protein	NA	NA	NA	NA
WP_010718433.1\|1833965_1834079_+	putative metal homeostasis protein	NA	NA	NA	NA
WP_010737897.1\|1834195_1834690_+	N-acetyltransferase	NA	NA	NA	NA
WP_010737896.1\|1834861_1836526_+	acetolactate synthase AlsS	NA	NA	NA	NA
WP_010718430.1\|1836538_1837249_+	acetolactate decarboxylase	NA	NA	NA	NA
WP_010737895.1\|1837408_1837897_+	GAF domain-containing protein	NA	NA	NA	NA
WP_010737894.1\|1838056_1838320_+	hypothetical protein	NA	NA	NA	NA
WP_010737892.1\|1839398_1839803_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_010737891.1\|1839830_1840469_+	nitroreductase family protein	NA	NA	NA	NA
WP_010718425.1\|1840484_1840772_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_014834545.1\|1841275_1843144_+	MucBP domain-containing protein	NA	NA	NA	NA
WP_014834546.1\|1843501_1843957_-	hypothetical protein	NA	NA	NA	NA
WP_010737889.1\|1844596_1844818_+	hypothetical protein	NA	NA	NA	NA
WP_071859353.1\|1845010_1845397_+	hypothetical protein	NA	NA	NA	NA
WP_010737888.1\|1846168_1847518_+	hypothetical protein	NA	NA	NA	NA
WP_010737887.1\|1847858_1849001_-\|integrase	site-specific integrase	A0A097PAS9	Streptococcus_pyogenes_phage	1.6e-68	43.0
WP_010737886.1\|1849107_1849563_-	NINE protein	A0A060AN66	Enterococcus_phage	1.8e-07	40.8
WP_002293175.1\|1849854_1850508_-	hypothetical protein	NA	NA	NA	NA
WP_002340827.1\|1850615_1851308_-	hypothetical protein	NA	NA	NA	NA
WP_010737885.1\|1851392_1851815_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_010737884.1\|1851832_1852153_-	helix-turn-helix transcriptional regulator	A0A182BQC8	Lactococcus_phage	1.2e-18	49.1
WP_002318514.1\|1852445_1852637_+	hypothetical protein	NA	NA	NA	NA
WP_010737883.1\|1852648_1852876_+	hypothetical protein	NA	NA	NA	NA
WP_010737882.1\|1852887_1853058_+	hypothetical protein	NA	NA	NA	NA
WP_010737881.1\|1853155_1853821_-	hypothetical protein	NA	NA	NA	NA
WP_002330647.1\|1853875_1854601_+	phage regulatory protein	D2IYT0	Enterococcus_phage	3.3e-27	35.5
WP_010737880.1\|1854776_1855118_+	hypothetical protein	NA	NA	NA	NA
WP_010737879.1\|1855110_1855845_+	DUF1071 domain-containing protein	A0A2I7RDU5	Vibrio_phage	1.6e-42	51.6
WP_010737878.1\|1855850_1856537_+	hypothetical protein	C9E2N1	Enterococcus_phage	6.4e-89	70.0
WP_010737877.1\|1856539_1857370_+	phage replisome organizer N-terminal domain-containing protein	C9E2N2	Enterococcus_phage	6.8e-53	45.2
WP_002323158.1\|1857386_1858238_+	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	6.2e-25	28.7
WP_002321420.1\|1858234_1858594_+	DUF1064 domain-containing protein	A0A1P8BKR1	Lactococcus_phage	1.1e-18	48.3
WP_002323911.1\|1858608_1858770_+	antitoxin	NA	NA	NA	NA
WP_014834549.1\|1858766_1859072_+	hypothetical protein	NA	NA	NA	NA
WP_002335860.1\|1859071_1859386_+	DUF1140 family protein	A0A2H4JAZ4	uncultured_Caudovirales_phage	1.3e-09	36.4
WP_010737874.1\|1859562_1859874_+	MazG-like family protein	D2IZY1	Enterococcus_phage	1.6e-34	73.7
WP_010737873.1\|1859874_1860096_+	hypothetical protein	NA	NA	NA	NA
WP_010737872.1\|1860092_1860389_+	hypothetical protein	NA	NA	NA	NA
WP_002304479.1\|1860465_1860879_+	autolysin	C9E2P5	Enterococcus_phage	1.1e-56	81.0
WP_010737870.1\|1862256_1862781_+	hypothetical protein	NA	NA	NA	NA
WP_010737869.1\|1862845_1863190_+	HNH endonuclease	A0A1B1P757	Bacillus_phage	3.8e-26	57.1
WP_010737868.1\|1863194_1863476_+	hypothetical protein	NA	NA	NA	NA
WP_002286538.1\|1863579_1863894_+\|terminase	terminase	A0A1S7FYW6	Listeria_phage	3.3e-08	37.9
WP_010737867.1\|1863871_1865566_+\|terminase	terminase large subunit	A0A1B1P766	Bacillus_phage	2.0e-147	49.6
WP_010737866.1\|1865585_1866764_+\|portal	phage portal protein	A0A1B1P754	Bacillus_phage	4.2e-80	40.4
WP_010737865.1\|1866726_1867413_+\|protease	Clp protease ClpP	A0A2I6PDD0	Staphylococcus_phage	6.1e-31	40.2
WP_010737864.1\|1867412_1868561_+\|capsid	phage major capsid protein	A0A1B1P752	Bacillus_phage	1.2e-95	49.4
WP_010737863.1\|1868570_1869446_+	hypothetical protein	D2IYX3	Enterococcus_phage	1.0e-128	74.2
WP_010737862.1\|1869442_1869754_+	hypothetical protein	A0A1B1P751	Bacillus_phage	5.4e-11	42.4
WP_002286522.1\|1869743_1870097_+\|head	phage head closure protein	NA	NA	NA	NA
WP_010737861.1\|1870086_1870488_+	hypothetical protein	A0A1B1P759	Bacillus_phage	1.8e-14	34.1
WP_010737860.1\|1870480_1870885_+	hypothetical protein	R4IBU7	Listeria_phage	6.1e-07	29.5
WP_002318244.1\|1870896_1871502_+	hypothetical protein	Q8W5Z9	Listeria_phage	6.7e-34	41.2
WP_010737859.1\|1871523_1871886_+	hypothetical protein	NA	NA	NA	NA
WP_002305377.1\|1871888_1872071_+	hypothetical protein	NA	NA	NA	NA
WP_010737858.1\|1872087_1875507_+\|tail	phage tail tape measure protein	A0A1D3SNL5	Enterococcus_phage	2.5e-77	41.8
WP_010737857.1\|1875557_1876295_+\|tail	phage tail protein	NA	NA	NA	NA
WP_010737856.1\|1876304_1878584_+\|tail	phage tail protein	A0A1D3SNL1	Enterococcus_phage	4.6e-83	28.8
WP_010737855.1\|1878606_1880799_+	hypothetical protein	A0A096XSZ6	Enterococcus_phage	7.3e-78	38.2
1879173:1879196	attL	NA	NA	NA	NA
WP_010718827.1\|1880884_1881106_+	hypothetical protein	C9E2K9	Enterococcus_phage	1.3e-16	60.3
WP_010737854.1\|1881105_1881309_+\|holin	phage holin	A0A0S2MYF6	Enterococcus_phage	1.7e-26	89.6
WP_010737853.1\|1881313_1882330_+	N-acetylmuramoyl-L-alanine amidase	A0A1G5SA77	Enterococcus_phage	8.3e-61	66.7
WP_010737852.1\|1882384_1883389_-	Abi family protein	A0A0N7IRA5	Lactobacillus_phage	4.3e-09	22.7
WP_002337238.1\|1883845_1884109_+	hypothetical protein	NA	NA	NA	NA
WP_010737851.1\|1884356_1884659_-	hypothetical protein	NA	NA	NA	NA
WP_052312484.1\|1885424_1886153_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_010718418.1\|1886337_1886673_+	SdpI family protein	NA	NA	NA	NA
WP_010718417.1\|1886669_1887386_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.4e-33	36.2
WP_010718416.1\|1887385_1888828_+	HAMP domain-containing histidine kinase	Q8QKV7	Ectocarpus_siliculosus_virus	5.9e-20	31.3
WP_010737849.1\|1888743_1890507_-\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.7e-130	47.7
WP_010718415.1\|1890875_1891382_-	hypothetical protein	NA	NA	NA	NA
WP_010737848.1\|1891368_1892097_-	hypothetical protein	NA	NA	NA	NA
WP_010737847.1\|1892425_1894567_-	LTA synthase family protein	W6LM83	Streptococcus_phage	1.3e-212	56.1
WP_010737846.1\|1894796_1895969_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	4.9e-105	52.6
WP_010737845.1\|1895982_1896732_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	4.2e-25	35.2
WP_014834553.1\|1896775_1897243_+\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
WP_010737843.1\|1897341_1898595_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	8.5e-23	53.8
WP_010737842.1\|1898708_1900058_+	NADP-specific glutamate dehydrogenase	NA	NA	NA	NA
WP_010718407.1\|1900170_1901517_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_010737841.1\|1901618_1902842_-\|integrase	site-specific integrase	A0A0P0I3D2	Lactobacillus_phage	2.5e-80	43.0
WP_010737840.1\|1903147_1904731_-	SIR2 family protein	A0A1S5SA14	Streptococcus_phage	1.1e-24	29.4
WP_014834555.1\|1904810_1904969_-	SHOCT domain-containing protein	A0A0F6N4L7	Staphylococcus_phage	6.5e-05	50.8
WP_010737839.1\|1905825_1906254_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_010737838.1\|1906260_1906641_-	helix-turn-helix transcriptional regulator	O03970	Lactobacillus_phage	5.5e-18	35.7
WP_010737837.1\|1906805_1907057_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_010737836.1\|1907053_1907305_+	hypothetical protein	NA	NA	NA	NA
WP_010737835.1\|1907245_1908073_-	TIGR02391 family protein	A0A1S5SBU1	Streptococcus_phage	3.6e-46	38.0
WP_010737834.1\|1908946_1909153_-	DUF3955 domain-containing protein	NA	NA	NA	NA
WP_010737833.1\|1909376_1909736_-	YxeA family protein	NA	NA	NA	NA
WP_010737832.1\|1910381_1910768_-	hypothetical protein	NA	NA	NA	NA
WP_010737831.1\|1910975_1911443_+	ArpU family transcriptional regulator	D7RWH7	Brochothrix_phage	2.4e-07	28.5
WP_010737830.1\|1912722_1913025_-	hypothetical protein	NA	NA	NA	NA
WP_010718386.1\|1913131_1913359_+	hypothetical protein	NA	NA	NA	NA
WP_010718385.1\|1913355_1913664_+	hypothetical protein	NA	NA	NA	NA
WP_010737829.1\|1913650_1915900_+\|plate	BppU family phage baseplate upper protein	A0A249XZH9	Enterococcus_phage	1.3e-45	36.4
1914457:1914480	attR	NA	NA	NA	NA
WP_010737828.1\|1915915_1916269_+	hypothetical protein	NA	NA	NA	NA
WP_010719481.1\|1916270_1916408_+	hypothetical protein	NA	NA	NA	NA
WP_010719480.1\|1916425_1916707_+	hypothetical protein	NA	NA	NA	NA
WP_010737827.1\|1916748_1917036_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_010737826.1\|1917019_1918000_+	N-acetylmuramoyl-L-alanine amidase	A0A0S2MY87	Enterococcus_phage	2.3e-55	61.6
WP_010737825.1\|1918320_1918584_+	hypothetical protein	NA	NA	NA	NA
WP_010718753.1\|1919158_1919308_+	hypothetical protein	NA	NA	NA	NA
WP_010718754.1\|1919652_1919850_+	cold-shock protein	Q9AZD3	Lactococcus_phage	1.7e-23	78.5
WP_010737824.1\|1920405_1921224_+	glycerophosphodiester phosphodiesterase family protein	A0A0S2MYI4	Enterococcus_phage	2.7e-09	35.5
WP_010737823.1\|1921277_1921502_+	hypothetical protein	C9E2K9	Enterococcus_phage	2.3e-16	60.3
WP_014834561.1\|1921540_1921696_+\|holin	holin	D2J076	Enterococcus_phage	6.8e-15	82.0
WP_010737822.1\|1921706_1922726_+	N-acetylmuramoyl-L-alanine amidase	A0A1G5SA77	Enterococcus_phage	2.6e-62	67.2
WP_014834562.1\|1922994_1923408_+	DUF4231 domain-containing protein	NA	NA	NA	NA
WP_002295273.1\|1923638_1923896_-	hypothetical protein	NA	NA	NA	NA
WP_010737820.1\|1924058_1925033_+	choloylglycine hydrolase family protein	M1HVK5	Paramecium_bursaria_Chlorella_virus	5.4e-25	31.8

DBSCAN-SWA_5

2512485 : 2521544

Prochlorococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010737442.1\|2512485_2513079_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.2e-24	34.6
WP_014834718.1\|2513075_2514017_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.5e-59	44.3
WP_010737440.1\|2514131_2515574_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	8.5e-51	32.9
WP_010737439.1\|2515558_2517781_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.6e-147	41.5
WP_010737438.1\|2517782_2518454_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_010737437.1\|2518455_2518710_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_010737436.1\|2518724_2519441_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	E3SPA9	Prochlorococcus_phage	9.7e-48	41.9
WP_010737435.1\|2519702_2520080_+	hypothetical protein	NA	NA	NA	NA
WP_010737434.1\|2520236_2521544_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	6.2e-16	27.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_018081

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection