CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_016946	Mycobacterium intracellulare ATCC 13950, complete sequence	7 crisprs	DEDDh,cas3,csa3,DinG,cas4,WYL,PD-DExK	1	2	385	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_016946_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016946_1

27124-27209

Orphan

Consensus_repeat	Method
CCGCCCTGCCCCTGGTCGGGGTAGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_016946_1

>merge|NC_016946|1|27124-27209|CRISPRCasFinder
CCGCCCTGCCCCTGGTCGGGGTAGCCGCGCTGGTCCTGGTAGCCCGGCTGCGGCGGGTAACCGCCTTGCCCCTGGTCGGGGTAGCC

>NC_016946|1|1|27124-27209|CRISPRCasFinder
CCGCCCTGCCCCTGGTCGGGGTAGCC	GCGCTGGTCCTGGTAGCCCGGCTGCGGCGGGTAA
CCGCCTTGCCCCTGGTCGGGGTAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_016946.1\|WP_009952750.1\|35460_36456_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NC_016946.1\|WP_009952755.1\|31822_32410_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|379237
NC_016946.1\|WP_179300602.1\|29268_29766_-\|DinB-family-protein	unknown	unknown	gnl\|CDD\|378981
NC_016946.1\|WP_014378756.1\|28846_29203_-\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|378915
NC_016946.1\|WP_041297605.1\|20013_21285_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NC_016946.1\|WP_029384183.1\|29990_30254_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|180304
NC_016946.1\|WP_008262550.1\|17472_18159_+\|aminodeoxychorismate/anthranilate-synthase-component-II	unknown	unknown	gnl\|CDD\|181107
NC_016946.1\|WP_009952754.1\|32707_34567_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237865
NC_016946.1\|WP_009952764.1\|24162_25677_-\|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl\|CDD\|223704
NC_016946.1\|WP_080587904.1\|15692_16118_-\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|371225
NC_016946.1\|WP_014378751.1\|21281_22760_-\|D,D-transpeptidase-PbpA	unknown	unknown	gnl\|CDD\|223839
NC_016946.1\|WP_020188378.1\|22756_24166_-\|FtsW/RodA/SpoVE-family-cell-cycle-protein	unknown	unknown	gnl\|CDD\|279444
NC_016946.1\|WP_009952752.1\|35144_35474_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|379642
NC_016946.1\|WP_009952753.1\|34570_34993_+\|hypothetical-protein	unknown	unknown	unknown
NC_016946.1\|WP_007771646.1\|25732_26200_-\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|224630
NC_016946.1\|WP_014378755.1\|28388_28826_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|317917
NC_016946.1\|WP_014378748.1\|16684_17428_+\|DUF881-domain-containing-protein	unknown	unknown	gnl\|CDD\|226396
NC_016946.1\|WP_014378749.1\|18136_20017_-\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	unknown	unknown	gnl\|CDD\|270916
NC_016946.1\|WP_009952757.1\|30250_31810_+\|long-chain-fatty-acid--ACP-ligase-MbtM	unknown	unknown	gnl\|CDD\|180289
NC_016946.1\|WP_003872098.1\|16273_16555_-\|cell-division-protein-CrgA	unknown	unknown	gnl\|CDD\|178907

Protein	Function_ID	Function_description	E-value
NC_016946.1\|WP_009952755.1\|31822_32410_-\|acetyltransferase	gnl\|CDD\|379237	pfam13523, Acetyltransf_8, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.33423e-47
NC_016946.1\|WP_179300602.1\|29268_29766_-\|DinB-family-protein	gnl\|CDD\|378981	pfam12867, DinB_2, DinB superfamily. The DinB family are an uncharacterized family of potential enzymes. The structure of these proteins is composed of a four helix bundle.	8.34185e-10
NC_016946.1\|WP_014378756.1\|28846_29203_-\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	2.19229e-11
NC_016946.1\|WP_041297605.1\|20013_21285_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.7491e-117
NC_016946.1\|WP_029384183.1\|29990_30254_+\|acyl-carrier-protein	gnl\|CDD\|180304	PRK05883, PRK05883, acyl carrier protein; Validated.	5.12886e-34
NC_016946.1\|WP_008262550.1\|17472_18159_+\|aminodeoxychorismate/anthranilate-synthase-component-II	gnl\|CDD\|181107	PRK07765, PRK07765, aminodeoxychorismate/anthranilate synthase component II.	7.58336e-154
NC_016946.1\|WP_009952754.1\|32707_34567_+\|hypothetical-protein	gnl\|CDD\|237865	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional.	0.00196497
NC_016946.1\|WP_009952764.1\|24162_25677_-\|protein-phosphatase-2C-domain-containing-protein	gnl\|CDD\|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	4.70422e-82
NC_016946.1\|WP_080587904.1\|15692_16118_-\|PH-domain-containing-protein	gnl\|CDD\|371225	pfam10756, bPH_6, Bacterial PH domain. This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.	4.64631e-16
NC_016946.1\|WP_014378751.1\|21281_22760_-\|D,D-transpeptidase-PbpA	gnl\|CDD\|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	7.19099e-104
NC_016946.1\|WP_020188378.1\|22756_24166_-\|FtsW/RodA/SpoVE-family-cell-cycle-protein	gnl\|CDD\|279444	pfam01098, FTSW_RODA_SPOVE, Cell cycle protein. This entry includes the following members; FtsW, RodA, SpoVE.	2.5414e-104
NC_016946.1\|WP_009952752.1\|35144_35474_-\|N-acetyltransferase	gnl\|CDD\|379642	pfam14542, Acetyltransf_CG, GCN5-related N-acetyl-transferase. This family of GCN5-related N-acetyl-transferases bind both CoA and acetyl-CoA. They are characterized by highly conserved glycine, a cysteine residue in the acetyl-CoA binding site near the acetyl group, their small size compared with other GNATs and a lack of of an obvious substrate-binding site. It is proposed that they transfer an acetyl group from acetyl-CoA to one or more unidentified aliphatic amines via an acetyl (cysteine) enzyme intermediate. The substrate might be another macromolecule.	2.49965e-27
NC_016946.1\|WP_009952750.1\|35460_36456_-\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	2.03046e-59
NC_016946.1\|WP_007771646.1\|25732_26200_-\|FHA-domain-containing-protein	gnl\|CDD\|224630	COG1716, COG1716, FOG: FHA domain [Signal transduction mechanisms].	1.27451e-31
NC_016946.1\|WP_014378755.1\|28388_28826_+\|hypothetical-protein	gnl\|CDD\|317917	pfam15599, Imm63, Immunity protein 63. A predicted immunity protein with an alpha+beta fold and a conserved E+G and ExxY motifs. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, which usually contains toxin domains of the Ntox40, Tox-CdiAC and Tox-ARC families. The protein is also found in poly-immunity loci in polymorphic toxin systems.	1.8184e-09
NC_016946.1\|WP_014378748.1\|16684_17428_+\|DUF881-domain-containing-protein	gnl\|CDD\|226396	COG3879, COG3879, Uncharacterized protein conserved in bacteria [Function unknown].	2.98972e-72
NC_016946.1\|WP_014378749.1\|18136_20017_-\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.49766e-130
NC_016946.1\|WP_009952757.1\|30250_31810_+\|long-chain-fatty-acid--ACP-ligase-MbtM	gnl\|CDD\|180289	PRK05851, PRK05851, long-chain-fatty acid--ACP ligase MbtM.	0
NC_016946.1\|WP_003872098.1\|16273_16555_-\|cell-division-protein-CrgA	gnl\|CDD\|178907	PRK00159, PRK00159, putative septation inhibitor protein; Reviewed.	9.68334e-47

>NC_016946.1|WP_007771646.1|25732_26200_-|FHA-domain-containing-protein
MQGLVLQLTRAGFLMLLWVFIWSVLRILRTDIYAPTGAVMVRRGLALRSTLLPSRQRRHAARYLVVTEGALAGGRITLSGQPVLIGRADDSTLVLTDDYASTRHARLSQRGSEWYVEDLGSTNGTYLDRAKVTTAVRVPIGTPIRIGKTAIELRP
>NC_016946.1|WP_009952764.1|24162_25677_-|protein-phosphatase-2C-domain-containing-protein
MAPVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHLDDDEPGGDLLAKLDNAVRSGNAAIAAQVEAEPELEGMGTTLTAILFAGDRIGLVHIGDSRGYLLRDGELSQITKDDTFVQTLVDEGRITREEAHSHPQRSLIMRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDETILEALQIPDVAEAAYRLIELALRGGGPDNVTVVVADVVDYDYGQTQPILAGAVSGDEDQMTLPNTSAGRASAIRPRDESAKRVAPQPETPHRPRWSRRRMVVVAALAVLLVVAGLTVGWWVIQRNYYVAEYNGRVSIVRGIQGTLLGVPLQRPYLVGCLNARNELALVSYGQSGHPNCQLMTLQDLRRPGQVQVQTGLPGGSLDQAESQLRQLLAEYLLPICPPPRATSPPGSPSTGGTPQSSTTATPSPPTTSSTSASPPPSTSASNGPATSSPAGPTTTSQTVTALPGPPPQPGIDCRTVA
>NC_016946.1|WP_020188378.1|22756_24166_-|FtsW/RodA/SpoVE-family-cell-cycle-protein
MTTQLQPPVAVTPPLPTRRNAELLLLGFASLITVAALLIVEANQTRDLHWDAINYGLVFLVVFGSAHMAIRRFAPYTDPLLLPIVALLNGLGLVMIHRLDLVTNQLSGRHHPSATQQMLWTLVGVVTFALVVTFLKDHRQLARYGYICGLVGLVLLVIPALLPASLSEQNGAKIWIRLPGFSIQPAEFSKILLLIFFSAVLIAKRGLFTSVGKHFMGLTLPRPRDLAPLLAAWVISVGVMAFEKDLGTSLLLYTSFLVVVYLATQRFSWVGIGLVLFVAGSVVAYFIFNHVRVRVQMWWDPFSDPDGSGYQIVQSLFSFATGGIFGTGLGNGQPDTVPAASTDFIIAAFGEELGLVGLASILMLYTIVIVRGMRTAIATRDSFGKLLAAGLASTLALQLFIVVGGVTQLIPLTGLTTPWMSYGGSSLLANYVLLAILARISHSARRPLRAPARHEPPIAAAGTEVIEKV
>NC_016946.1|WP_014378751.1|21281_22760_-|D,D-transpeptidase-PbpA
MNASLRRISVTVMALIVLLLINATMTQVFAADSLRADPRNQRVLLDEYSRQRGQIVAGGQLLAYSVATDNRFRFLRVYPNPATYAPVTGFYSLRYSSTGLERAEDPLLNGSDERLFGRRLADFFTGRDPRGANVDTTIKPRVQQAAWDGMQQGCGGPPCKGAVVALEPSTGKILAMVSSPSYDPNLLSSHDPEVQAKAWQVLRDDPDNPMTNRAISETYPPGSTFKVITTAAALQAGASDTEQLTAAPSIPLPNSTATLENYGGQSCGNEPTVSLQQAFALSCNTAFVQLGMLTGSDALRGMARSFGLDSTPSVIPLQVAESTIGIIPDAAALGMSSIGQKDVAMTPLQNAEIAATIANGGVTMQPYLIDSLKGPDLTTISTTAPYEQRRAVSPQVAAKLTELMVGAEKVAQQKGAIPGVQIASKTGTAEHGTDPRHTPPHAWYIAFAPAQTPKVAVAVLVENGADRLSATGGALAAPIGRAVIQAALQGGP
>NC_016946.1|WP_041297605.1|20013_21285_-|serine/threonine-protein-kinase
MSPRVGVTLSGRYRLQRLIATGGMGQVWEAVDSRLGRRVAVKVLKQEFSQDPEFIERFRAEARTTAMLNHPGIAAVHDYGESQLDGEGRTAYLVMELVNGEPLNSVLKRTGRLSLRHALDMLEQTGRALQVAHAAGLVHRDVKPGNILITPTGQVKITDFGIAKAVDAAPVTQTGMVMGTAQYIAPEQALGHDATPSSDVYSLGVVGYEVVSGKRPFTGDGALTVAMKHIKEPPPPLPAELPPNVRELIEITLVKNPAMRYRSGGPFADAVAAVRAGRRPPRPSQSPPPGRASPAAIPSSPTTRAAAVSPRSAAPRRSRPTTGGHRPPPARRTFSSGQRALLWAAGVLGALAIIIAVLIVINSRGDQQQQPPTVTDTGTPPASAPAPTNTPSGSAGMRLEWPDDGTIGMSGFRGGPAGHGTSQ
>NC_016946.1|WP_014378749.1|18136_20017_-|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase
MTTPQHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREAQNAAALNHPSIVAVYDTGEAETPTGPLPYIVMEYVDGVTLRDIVHTDGPLPPRRAIEIIADACQALNFSHQNGIIHRDVKPANIMISTTNAVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDAVDARSDVYSLGCVLYEILTGEPPFVGDSPVAVAYQHVREDPVPPSQRHDGISPDLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEKPEAPKVFTDADRSSMLSSNPGSGGPPPTDPLPRQVLADAGEDRTVGSVGRWIVAVAALAVLTIVVVIAFNTFGGGARDVQVPDVRGQVSADAIAALQNRGFKTRTLQKPDSIVPPDHVIGTDPGANASVSAGDEITVNVSTGPEQREVPDVSSLSYSDAVTKLKAAGFTKFKQANSPSTPELLGKVIGTNPPANQTSAITNVITVIVGSGPETKQVPDIAGQTVDIAQRNLTVYGFSKVTQVQVDSPRPAGEVIGTNPPKGQMVPVDSVIELQVSKGNQFVMPDLSGMFWTDAEPRLRALGWTGILDKGADVDAGGSQSHRVVYQNPPAGSGVNRDGIITLKFGQ
>NC_016946.1|WP_008262550.1|17472_18159_+|aminodeoxychorismate/anthranilate-synthase-component-II
MRILVVDNYDSFVFNLVQYLGQLGVDADVWRNDDDRLSDETAAARQFDGVLLSPGPGTPERAGASIGMVRACAAEQTPLLGVCLGHQAIGVAFGATVDRAPELLHGKTSSVHHTNVGVLQGLPDPFTATRYHSLTILPESLPPVLEVTAHTDSGVIMGVRHAELPIHGVQFHPESILTEGGHRMLANWLAVCGLVRNDTLVRRLENDVHAAVRPYFPADPAATDRTSA
>NC_016946.1|WP_014378748.1|16684_17428_+|DUF881-domain-containing-protein
MIQTRQSPWRFGVPVVCALAGLLLAATHGVSGGAEIRGSDAPRLVDLVRETQSSVNRLNAEREELAKKIDTAHGRSSDAALAAMLRRSAQLAGQADMNPVHGPGLVVTLEDAQRDANGRFPRDASPDDLVVHQQDIQAVLNALWSAGAEAIQMQDQRLIATSVPRCVGNTLLLNGRTYSPPYTITAIGNSAAMQAALAAAPLVVLYKQYVVRFGLGYREEVKSDAQVVGHFEPDRLHYAQPNGPIAY
>NC_016946.1|WP_003872098.1|16273_16555_-|cell-division-protein-CrgA
MPKSKVRKKNDFTVSAVSRTPVKVKVGPSSVWFVALFIGLMLIGLVWLMVFQLAAVGSQAPTALNWMAQLGPWNYAIAFAFMITGLLLTMRWH
>NC_016946.1|WP_080587904.1|15692_16118_-|PH-domain-containing-protein
MQQTQWEPHATGIAGCGAAGVLLAIAGVTLITDPPGRVLAGVAAGGLLLFAGMSWRARPKLAITPDGLALRGWFRTQLLQQSDIKIIRIIEFRRYGRKVRLLEVETADGGLVLFSRWDLGTDPLDVLDALTAAGYAGRSQP
>NC_016946.1|WP_014378755.1|28388_28826_+|hypothetical-protein
MVDDKTAHLQSEVNRIAALLNARPIQAGVVLKDDDRNIYIDDDGRYHYDYWERGRQKVDHVGDIDEALYWFACDIAFDIGGSSSARHCPRDQDPRILMWAKQYEVLNRVNPGWATRCVRETAELLRRWGRHDDVALLPNIPGRDG
>NC_016946.1|WP_014378756.1|28846_29203_-|nuclear-transport-factor-2-family-protein
MNVDADAFSKRWAQRWNAHDVDAVLDDFHDDVVFTSPVAAKLLPETQGVVRGKAALRRYWIAALERIPDLRFTVEGVYQGVNTIVIAYRNQNGDLVNEVLIFDGEVIVEGHGTYRVGE
>NC_016946.1|WP_179300602.1|29268_29766_-|DinB-family-protein
MTEPCAGCGFAYDLRRAASVRHDIRALAAEAVVLLSNNKIDVRSRSRPDVWSPLEYACHLRDVLLVQRERVLAARRTNGHDCASMGRGERAEHDGYSEQDPAEVARQLADAAALFSNVLARLSADDWDRTVIYHYPETHERSLRWVAVHTVHELQHHLLDIRRQL
>NC_016946.1|WP_029384183.1|29990_30254_+|acyl-carrier-protein
MTSFNPPVPSTVDDQLVSVLRDDLDLKFESVTAATRLIDDLGMDSVAFAAGLVAIEERFGTQLSEEDLLTCTTVGDLQAAIGVGVDA
>NC_016946.1|WP_009952757.1|30250_31810_+|long-chain-fatty-acid--ACP-ligase-MbtM
MNVLAAAMRDAMTRSPHDLVVLDKDTDKWTARPWPEVHGMAESIATHLLQQDHLGAVGIVGEPTVELVAAIQGAWLAGAAVSILPRPRRGADPAEWAHSTLSRFRGIGVSTVFSHGATLRTLGDAESTLSVSSLAEAARTPASNDLQSHSDSNAAILQGTAGSTGDPRTAVLSPEAVLNNMRGLIERLQLDGSDRACSWLPIYHDMGLAFLLTAVLSGMPLWQAPTGAFSAAPLRWADWLSASAATFTAGPNFGYSMLGRYSGRVSDVDLGALRIAINGGEPVDCEGFQRFADAMAPFGLRASAATPAYGMAESTCAVTMPACGQGLRIDERTESDVRQRYALLGPPIPGMELRISPTHRSADDGVGEVEIRGSSMMTKYFGDPATGSDRGAEWFRTGDIGYLVDGELVICGRSKEVITIAGRNIFPTEIEQVAAQVDGVRHGGVVAVGSKSGAAQSRLLIAAEFVGSDHDVTRSAVIKRVISVCGVTPADVVLMPPGSLPRTSSGKLRRLEVRSQLQA
>NC_016946.1|WP_009952755.1|31822_32410_-|acetyltransferase
MLARELTDITDSVRQVPAPPVPELLPPSRIRVADPDGADAELVAEWMNRPHLVTTWEYDWPVARWRNHLRAQVDGAYSRPLILSINGVDRAYMEIYRAAKDSIARCYDSRPHDLGLHGAIADEELVNRGLGPLILRKVIASILAVDPACQRIMFDPDHRNTTVRRLCEFLRCEFLGEHDMPNRRMALYALNRPAP
>NC_016946.1|WP_009952754.1|32707_34567_+|hypothetical-protein
MGLPYIDEQALIAEAGGDPWAINASLQAGSPLEISNLAGAFHRAGRCTAEAENAFQQARARFEAAWNHHDGGGHPINDSDEVQRVTKSLGAQSLQLPKIAADLENIAASLADAQKAGAARIATLEAQLKNISDMVSQAVSILQNDKSLSAGEKDALHALINTCEDDALRDTKAALAALQSIRNGYADGLQKSLDNLHAEGYDGAPLHGADADGVAPPSPAQQAALADIRQATNQAVVDQMAKVRAAQEALSKAAADLYTHGPGSPEGEAASAKLPKLKADLARALDDLGKIPDYNSIDPASVSVSPDGHFTFTYKVNGQPVQAYGQLKNGTGEFFDQATGTYYTFNGGKLTGMRTPDPGKVEATAEPLFTAVTLAAGAPALKAGGEAAFQGLKMLFSREMLEGVTADNVFPRALAGAEERFQAAEQNLASHAPLPGEPVPGTHPLEPPPVEHAPPAPHGDVPVEHAPAGPHVGALPDSPAPVVIDPAHPEFHLDNPLNYMTPELRAMAEAHLTGSGETVLGPFRPPGGGPSYIQVAEDRGASYFSLGDAWDSFTPTEQLAANQHVLDVAISNQDKITLSVPFHRVPPNSFTAAELRYLEAHGYRRIGENTLLPPSEGAR
>NC_016946.1|WP_009952753.1|34570_34993_+|hypothetical-protein
MKTLLEFFLHYFDFLYLDPRYHVTNSTTSGNPLSNASLTLTGPVISWELTNDRGQLGFVIAPTTLAESPDNWFRATLIRQYLDDYDETNVVSPRETVAWIRSNLSRIEQLFIEPETERSCEELLNLAKALAIKYFGPPQG
>NC_016946.1|WP_009952752.1|35144_35474_-|N-acetyltransferase
MTTDKTGAETAVTLEDGKYTIAVEGKTVGLADFADRGEQRVFYHTEIDPAYGGRGLATILVEEALNEARDEGKRIVPVCSMIGTVLKKHPEFDDITDPVTPEITQWVRS
>NC_016946.1|WP_009952750.1|35460_36456_-|pirin-family-protein
MSNLEAAPAEVACAASQRRDASPRVEVLHPREVPLGGPRAIRVQRTLPQRGRSLIGAWCFIDHYGPVAARMDVPPHPHTGLQTVSWLFSGEVEHRDSAGVRAVVRPGELNLMTAGAGICHSEVSVDAGPVLHGVQLWVALPAAARDTARDFAHYAPPVVPLPGAQARVFLGELAGSRSPTKTFSPLLGAQLDLDADAGFDIDVDPTFEHGVLCDSGTVQVDGTSLAIADLAYLSPGHTQLHVRNVGERPARVLLLGGTPFTEELVMWWNFVGRSHEDIVNYRRLWEDDDDRFGAVHGYRGALARLPAPPLPTARLRPRPIPRRKESTNDNR

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Crispr_ID: NC_016946_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016946_2

1580763-1580845

Orphan

Consensus_repeat	Method
CGCCCGGCGGCGCCGCGCTCGCGATCGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_016946_2

>merge|NC_016946|2|1580763-1580845|CRISPRCasFinder
CGCCCGGCGGCGCCGCGCTCGCGATCGGCTTGATCTACGCGCGCCGACCCGCTTCGCCCGGCGGCGCCGCGCTCGCGATCGGC

>NC_016946|2|2|1580763-1580845|CRISPRCasFinder
CGCCCGGCGGCGCCGCGCTCGCGATCGGC	TTGATCTACGCGCGCCGACCCGCTT
CGCCCGGCGGCGCCGCGCTCGCGATCGGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_016946.1\|WP_014379573.1\|1579329_1580718_+\|amidase	unknown	unknown	gnl\|CDD\|171524
NC_016946.1\|WP_014379570.1\|1571675_1572512_+\|uracil-DNA-glycosylase	unknown	unknown	gnl\|CDD\|381681
NC_016946.1\|WP_009953967.1\|1573686_1574718_+\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274646
NC_016946.1\|WP_036458463.1\|1578811_1579246_-\|HIT-family-protein	unknown	unknown	gnl\|CDD\|238608
NC_016946.1\|WP_014382055.1\|1581361_1582486_+\|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl\|CDD\|374736
NC_016946.1\|WP_026071521.1\|1566790_1568245_+\|MCE-family-protein	unknown	unknown	gnl\|CDD\|224380
NC_016946.1\|WP_009953976.1\|1589753_1590284_+\|DUF3558-domain-containing-protein	unknown	unknown	gnl\|CDD\|378803
NC_016946.1\|WP_014379571.1\|1574725_1578592_-\|bifunctional-diguanylate-cyclase/phosphodiesterase	unknown	unknown	gnl\|CDD\|238923
NC_016946.1\|WP_009953966.1\|1572508_1573639_+\|FAD-binding-protein	unknown	unknown	gnl\|CDD\|180297
NC_016946.1\|WP_009953974.1\|1585326_1587243_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_016946.1\|WP_009953960.1\|1568287_1568893_+\|hypothetical-protein	unknown	unknown	unknown
NC_016946.1\|WP_009953964.1\|1570241_1571609_-\|FAD-binding-protein	unknown	unknown	gnl\|CDD\|273050
NC_016946.1\|WP_008254722.1\|1589187_1589745_+\|DUF3558-domain-containing-protein	unknown	unknown	gnl\|CDD\|378803
NC_016946.1\|WP_014379577.1\|1591042_1592194_+\|exonuclease-SbcCD-subunit-D	unknown	unknown	gnl\|CDD\|223497
NC_016946.1\|WP_009953977.1\|1590376_1590880_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|224973
NC_016946.1\|WP_009953975.1\|1587239_1589006_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_016946.1\|WP_009953961.1\|1568889_1569552_+\|hypothetical-protein	unknown	unknown	unknown
NC_016946.1\|WP_008254711.1\|1582765_1583338_+\|hypothetical-protein	unknown	unknown	unknown
NC_016946.1\|WP_008254716.1\|1583381_1585148_-\|sensor-domain-containing-protein	unknown	unknown	gnl\|CDD\|270916
NC_016946.1\|WP_014379578.1\|1592190_1594812_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|227061

Protein	Function_ID	Function_description	E-value
NC_016946.1\|WP_014379573.1\|1579329_1580718_+\|amidase	gnl\|CDD\|171524	PRK12470, PRK12470, amidase; Provisional.	0
NC_016946.1\|WP_014379570.1\|1571675_1572512_+\|uracil-DNA-glycosylase	gnl\|CDD\|381681	cd10031, UDG-F5_TTUDGB_like, Uracil DNA glycosylase family 5, includes Thermotoga maritima TTUDGB and similar proteins. Uracil DNA glycosylase family 5 includes Thermus thermophilus HB8 TTUDGB (also called UDGb) which is not only a UDG acting on double-stranded uracil-containing DNA, but also a hypoxanthine DNA glycosylase acting on double-stranded hypoxanthine-containing DNA (except for the C/I base pair), as well as a xanthine DNA glycosylase acting on both, double-stranded and single-stranded xanthine-containing DNA. TTUDGB also excises thymine from G:T mismatched DNA, and removes analogs of uracil from DNA, including 5-hydroxymethyluracil (hmU) and 5-fluorouracil (fU). This subfamily also contains Bradyrhizobium diazoefficiens family 5 homolog Blr5068 (UdgB) which has been found to efficiently excise uracil from ssDNA and dsDNA. Uracil-DNA glycosylases (UDGs) initiate repair of uracils in DNA. Similar to family 4 UDGs, members of this family possess four conserved cysteine residues required to coordinate the [4Fe-4S] iron-sulfur cluster. Uracil in DNA can arise as a result of mis-incorporation of dUMP residues by DNA polymerase or via deamination of cytosine. Uracil in DNA mispaired with guanine is one of the major pro-mutagenic events, causing G:C->A:T mutations. Thus, UDG is an essential enzyme for maintaining the integrity of genetic information. UDGs have been classified into various families on the basis of their substrate specificity, conserved motifs, and structural similarities. Although these families demonstrate different substrate specificities, often the function of one enzyme can be complemented by the other.	8.37425e-114
NC_016946.1\|WP_009953967.1\|1573686_1574718_+\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274646	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1. The Pfam domain family pfam00296 is named for luciferase-like monooxygenases, but the family also contains several coenzyme F420-dependent enzymes. This protein family represents a well-resolved clade within family pfam00296 and shows no restriction to coenzyme F420-positive species, unlike some other clades within pfam00296. [Unknown function, Enzymes of unknown specificity].	3.29337e-139
NC_016946.1\|WP_036458463.1\|1578811_1579246_-\|HIT-family-protein	gnl\|CDD\|238608	cd01277, HINT_subgroup, HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life. Although the biochemical function has not been characterised for many of the members of this subgroup, the proteins from Yeast have been shown to be involved in secretion, peroxisome formation and gene expression.	1.92607e-50
NC_016946.1\|WP_014382055.1\|1581361_1582486_+\|adenylate/guanylate-cyclase-domain-containing-protein	gnl\|CDD\|374736	pfam16701, Ad_Cy_reg, Adenylate cyclase regulatory domain. This domain regulates the activity of Actinobacterial adenylate cyclase in a pH-dependent manner, allowing activation at acidic pH.	8.00421e-95
NC_016946.1\|WP_026071521.1\|1566790_1568245_+\|MCE-family-protein	gnl\|CDD\|224380	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism].	6.3405e-66
NC_016946.1\|WP_009953976.1\|1589753_1590284_+\|DUF3558-domain-containing-protein	gnl\|CDD\|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	6.49783e-31
NC_016946.1\|WP_014379571.1\|1574725_1578592_-\|bifunctional-diguanylate-cyclase/phosphodiesterase	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.93244e-82
NC_016946.1\|WP_009953966.1\|1572508_1573639_+\|FAD-binding-protein	gnl\|CDD\|180297	PRK05868, PRK05868, FAD-binding protein.	0
NC_016946.1\|WP_009953974.1\|1585326_1587243_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NC_016946.1\|WP_009953964.1\|1570241_1571609_-\|FAD-binding-protein	gnl\|CDD\|273050	TIGR00387, Glycolate_oxidase_subunit_glcD., glycolate oxidase, subunit GlcD. This protein, the glycolate oxidase GlcD subunit, is similar in sequence to that of several D-lactate dehydrogenases, including that of E. coli. The glycolate oxidase has been found to have some D-lactate dehydrogenase activity. [Energy metabolism, Other].	9.15276e-135
NC_016946.1\|WP_008254722.1\|1589187_1589745_+\|DUF3558-domain-containing-protein	gnl\|CDD\|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	4.57725e-31
NC_016946.1\|WP_014379577.1\|1591042_1592194_+\|exonuclease-SbcCD-subunit-D	gnl\|CDD\|223497	COG0420, SbcD, DNA repair exonuclease [DNA replication, recombination, and repair].	2.98224e-63
NC_016946.1\|WP_009953977.1\|1590376_1590880_-\|histidine-phosphatase-family-protein	gnl\|CDD\|224973	COG2062, SixA, Phosphohistidine phosphatase SixA [Signal transduction mechanisms].	1.422e-43
NC_016946.1\|WP_009953975.1\|1587239_1589006_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.34723e-158
NC_016946.1\|WP_008254716.1\|1583381_1585148_-\|sensor-domain-containing-protein	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.17318e-119
NC_016946.1\|WP_014379578.1\|1592190_1594812_+\|AAA-family-ATPase	gnl\|CDD\|227061	COG4717, COG4717, Uncharacterized conserved protein [Function unknown].	2.14957e-10

>NC_016946.1|WP_014379573.1|1579329_1580718_+|amidase
MNDDLAFAGAAAQARMLADGELTAPELLEVYLERIAQLDSQLRCYRVVLADKARYEAAVAQDRLDAGERLPLLGVPVAIKDDVDVAGEVTTFGSGGHRPAVSSDAEVVRRLRAAGAVIVGKTNVPELMMLPYTESLTFGATRNPWDPRRTPGGSSGGSAAAVAAGLAPLALGSDGGGSIRIPATWCGVFGLKPQRDRVSLEPHDDAWYGLSVNGPIARTVIDAAVFLDATSTVPGPEGEFVTAATRSPGRLRIALSTKVPTPLPVRVGKRELAAVDEAGALLRDLGHDVITADPEYPASAILTNYLPRYLRGICDDADALAHPERLEPRTRNMARLGSFFSDRRMESLRAAEGAVVSRIQAIFDDVDVVVTPGTATGPSRIGAYQRRGAVSTLLRVGQYVPYQQVWNLTGQPAAVVPWDLDADGMPMSVQLVGRPYDEATLLSLSAQIEAARPWALRRPPVS
>NC_016946.1|WP_036458463.1|1578811_1579246_-|HIT-family-protein
MSCVFCAVVAGEAPAIRIYEDDDYLAILDIRPFTRGHTLVLPKRHSVDLTDTTPETLAGMVTLGQRIARAARTTELADATNIAINDGSAAFQTVFHVHLHVLPRRNGDKLSVAKGMLLRRDPDRDATGQILRNALARIDASQPD
>NC_016946.1|WP_014379571.1|1574725_1578592_-|bifunctional-diguanylate-cyclase/phosphodiesterase
MYGVAGVLIVLSSFWGWRGPYGTHPINGFVIAMCLAIAAAYAARAARFKPRRQRYGWLALVTALLGWAAGEVIWAFYDVRPEFDHATHPAATEFVLLLWPVGAMTSLVLLSQLSRKSPRRLLLDGLIVATSLFVIAWVFVVEAQLQEHSGARLVTSAEVFADIVQVTTAILMLSRARPGDRPSRSLLAAGVATICIADMALVFYTGIASYHTGGVGDLVRVAGLALLALAALAAAHERPAPAPPDETEFRARLWLPYLPLILAAAAGWAHAAGHSIHDPMLAALGILVAAVLARQFVVLVDNQNLLSEVAREAFRDNLTGLANRALFLQRLEQAVARRHPNGMPIAVLCLDLDNFKSVNDALGHPAGDELLVRVAGRLTAALGESGTIARLGGDEFAAVIEASVQESQAAAHRILDAFTGAILIDGIPIMVRPSIGFTVCTGASACTVDQLLRHADLAMYAAKREGGQCIRSFMPDLPLPYAFPASPDSGESDVAPPVDGGGGVATPQASPPVSDLATPTTNSPSGDVGDDAPRPPRGIRVGFAVLAVGVIAFAASSVAHPDAGHGMFSATTLYSALTVLAAGLVVLRAYRVSADRLAWSLIAAGMAFSAAGDIVYALFVPNGRSPSVADPVYLAYYPLVYAGLLLLMRARFKRLPIPIQLDSLVCALTLAAVAAAVTEGPMRAATSRTPATVWMGLVYPWIDLVLLALAAGMLPILGWRNDFRWALLMTGLVVFAVADVAYLFQTTAGSYRVGTLLDACWPASSLLIAMASWSPSSPTAPVPRHRFSPYVTPVTTSVVALGVIVLAHHSRPAATLAALSLVVATARFSLTFRDVSLLHTNAKHAMTDELTALPNRHSLASALTALPTTAPGPTSIPGRARARRALLLLSLSDFHEITDSIGRHFGDELLCHIANRLSGSVRRDDMLARVGDDQFAVLLADGANLTAASAQAGRLLEALSEPIALDPITVQVEGRIAIALCPDHCDHPQELLGRAETAMAHAESARSKIAVYDSSFEVYRNNDPNLIEDLRTALFDTDELKLHYQPKIDGRDGSVHSVEAVLRWQHPTRGTLLPEEVLPVAERAGLMRKISNRTLSMALKQVRCWREQGITLTVAVNLSTTNLLDIELVGTVERLLANYDLPADALILEITESALVDSARSRNTVAALQRLGIRISLDDYGTGWSSLARLQEVSVDELKLDRIFVTRLDHDARSVAIVRSTVALAHNLGADLVAEGVENKGTLDALHRYGCMITQGYVHTAPLPPDELRNWIANHTPEPHTSQSHRRA
>NC_016946.1|WP_009953967.1|1573686_1574718_+|LLM-class-flavin-dependent-oxidoreductase
MRLSVLDLIPVRTDQTTGDALAATVQLAQAADRLGFTRYWVAEHHNMPSVGATSPPVVLAYLAPQTSQLRLGSGGVMLPNHAPLAVAEQFALLEAAAPGRIDLGIGRAPGSDPVTSYALRGGQDGRDIENFPEYLDDVAALMSARGVRVPLRSGDYTLKATPAAATEPRLWLLGSSMYSAHLAAAKGLPYVFAHHFSGKGTEEALEVYRARFTPSAFAAEPRTFLTVNAAVAETQQEATALMLPNLQMMARLRTGQPLGPVPLVEEAAVAELTGQQQAIVDSGLRRAVLGTPAEAAEQIRALAEHFGVDEVMVNPVASARRGTDPDTAPARVATLELLAKELF
>NC_016946.1|WP_009953966.1|1572508_1573639_+|FAD-binding-protein
MSEILVSGASVAGTAAAFWLGRHGHSVTVVERHTGPRPGGQAIDVRGPALTVLDRMGLLAAAEKRKTQIRGSSVVDRDGNELSRDTESTPTGGRIDSPDIELLRDDLVELLYGASQWTTDYLFDDTITALEADGAAVRVTFERAAPREFDLVVGADGLHSNVRRLVFGPEEDFIERLGTHAAIFTVPNFLDLDHWQMWHYGDSTMAGIYSARHNAEARAMLGFMDPELRIDYRDTEAQFAELERRMAGEGWVRPQLLEYMRTAPDFYFDEMSQIKMDRWSHGRVVLVGDAGYCCSPLSGQGTSVALLGAYVLAGELKSATSDGTADHERGFANYHREFADYVQRNQWLVVDNIPGGAPIPQEVFDRIVSSITLKDY
>NC_016946.1|WP_014379570.1|1571675_1572512_+|uracil-DNA-glycosylase
MQDVHVLDHPRTGQPFDSPVGAGTGWPGDPATPQTPVAADAARVVALAEQATSIPELDALVSVCRACPRLVDWREEVARVKRRAFADQPYWGRPVPSWGAARPRLLIVGLAPAAHGANRTGRMFTGDRSGDQLYAALYRAGLVNQPTSVDAADGLRTNQIRIVAPVRCAPPANAPTPAERDTCWPWLQAEWQLVADHVRVVVALGGFGWQIALRLPGTSGRAARPKPRFGHGAVADLAPGVRLLGCYHPSQQNMFTGRLTPAMLDDIFRDAKELAGIK
>NC_016946.1|WP_009953964.1|1570241_1571609_-|FAD-binding-protein
MSSDALASLIADLPDGMVVTDPTVTEGYRQDRAFDPSAGKPLAVVRPRRTEEVQTVLRWATANRVPVVPRGAGSGLSGGATALDNCIVLSTEKMRDISVDPVTRTAVCQPGLFNAEVKKAAAEHGLWYPPDPSSFEICSIGGNIATNAGGLCCVKYGVTTDYVLGMQVVLADGTAVRLGGPRLKDVAGLSLTKLFVGSEGTLGVVTEVTLRLVPKQNASSVVVATFASVQDAVDAVLGVTARLRPSMLEFMDSVAINAVEDTLRMDLDRGAAAMLVAGSDERGRAGSEDAEIMAKVFAENAATEVFSTDDPDEGEAFVVARRFCIPAVEAKGSLLLEDVGVPLPALGRLVTGIAGIAAERDLMISVIAHAGDGNTHPLIVYDPADADMTERAHLAFGEIMDLAVGLGGTITGEHGVGRLKRPWLAGYLGPEVMDLNRRIKQALDPQGILNPGSGI
>NC_016946.1|WP_009953961.1|1568889_1569552_+|hypothetical-protein
MKFPKLLRRADDHTNVASSEEAPATPGPTAIAGDKPDTDVATTEVDESGDRQSSTPAKHHIRWARAIVYALLPGLALSLAVAAGFLKWQGGSARTAQLAATESVRTATESTIALLSYRADSVEKDLEAARSRLTGKFLNAYTSLTHDVVIPGAKQKHISASATVPAAAPIEATGSHAVVLLFVNQTVTIGQDSPTNSASSVRVTLDKVDGRWLIAEFDPI
>NC_016946.1|WP_009953960.1|1568287_1568893_+|hypothetical-protein
MREAVDFHASPGGDVVDADGDTIESDIDPTENASTPRSAESVFHLRPTIRVCLTIVVALSVLVGWLGFRSYQTHQAQIQRNQFLQVARQGALNLTTIDWRHADTDVQRILDGATGQLHDDFAKRSKPFIEVVKQAKAITVGTISSAGLESETADTAQVLVAMTVQTSDAAASDQAPRAWRMRIFVQKTDGQVKVSNVEFVP
>NC_016946.1|WP_026071521.1|1566790_1568245_+|MCE-family-protein
MRLGLQIWIKLSIFAAVSGIAAAVTVFGYIKVENLIPGLGQYKVTVQLSQAGGLYKRANVTYRGTYVGRVKDVRITPTGVDAVLLLKSGLDIPSDLDAQVHSQSSVGEQYVSLLPRNGNSRPLRDGDVIPENHTSVPPDINTLLNATNRALEAIPRDNLKTVIDESYTAVGGLGPELSRIVKGSTALATDARKNVDSLTALIDQSQPVLDSQAGTSPSILAWSKHLATITDQLQGHDAAVAGVLEKGGPAANEVRQLFDRLRPTLPIMLANLVSIGQVAVTYRNDIEQLLVLLPQATAVQAGGDVPNMGTKQAYRGYYLDFNLNLNLPPLCTTGFLPAQQHRVPEVDYPDRPAGDLYCRAPQDSPLAVRGVRNVPCETVPGKRAPTVKMCESNEHYVPLNDGFNWKGDPNATLSGQGIPQLPPGSPPAVAGPPASAPPPIAAAQYDPATGTYIGPDGHQYTQSDLAQTAPKDKTWQTMLMPPGS
>NC_016946.1|WP_014382055.1|1581361_1582486_+|adenylate/guanylate-cyclase-domain-containing-protein
MHDGDDHTIDDLLEGLEGTARTERAELVRWLFEQGITAEEIRATNPPLLLATRHIIGDDGTYVSTREISETHGIDLGLLQRVQRAIGLVRVDDPDAAVHMRADGEAAAFTQRFVELGLDPEHVILVVRVLAEGLSRTAEVMRYSALSAIMRPGASELEIAQASKALVTKIAPMLGPMIQHMLFMQLRHMMETEAVNAAERAAGKPLPGARQISVAFADLVGFTRIGEAVTPEELGHLANRLAILARDMTVPPVRFIKTIGDAVMFVCPEPQPLLDVVLKLVEAVDSDNDFPRLRAGVASGMAVSRAGDWFGSPVNVASRVTSVARPGTVLAADSVWEVIGERGEFSASFAGSRHLKGIKGEVKLFRIRRGDAED
>NC_016946.1|WP_008254711.1|1582765_1583338_+|hypothetical-protein
MKAHHTHGRRYGRPGGWQQAQQPDAGDAAEWFAGRLPEKWFDGDPTVIVDREEITVMGRLPDTASAESGESEARAAGRASRFREETRSERMHIADEAQDRYGRKVSWGVEVGSERILFTHIAVPVMTRLKQPERQVLDTLVDAGVARSRADALAWSVKLVGEHAEEWLAKLRDAMTAVDDLRAQGPDLQS
>NC_016946.1|WP_008254716.1|1583381_1585148_-|sensor-domain-containing-protein
MSDEQASRAGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLSESFSRDPVFRERMKREARTAGRLQEPHVVPVHDYGEIDGQIFLEMRLVEGTDLDSVLKRFGPLTPPRAVAVITQIASALDAAHAAGVMHRDVKPQNILVTADDFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSDAEVTYRADIYALACVLFECLTGAPPYRADSAGMLVSAHMMDPIPAPSQRRPDIPKAFDAVIARGMAKRPEDRYASAGDLALAAKQALSHPDQDRAATILRRSQEAALPTAVNPDPRLSTAPPPRPYQPAFNTPPPSPSAAPYYQGASANWGGPPPQFANATPWGQPPPRPRRNVWLIVAAVAVVFVLLGSGLGIWLVTRPDPEPPPPAPLEADRLSALLLGPSDINTVMGSSTMQPGKPITSTDHSAVTVSTPDCQGALYTTQDPVYAGTGYTSVSGLVSSEPGDNYDHWVNQAVVLFPSADKAKSFLENSAEKWKGCAGKTVTVTNKSKTYRWTFAQVQGSPPKITLMDTQEGADGWECQRALTVANNVIVDINACGYHISDQGAQIADKIAARIADE
>NC_016946.1|WP_009953974.1|1585326_1587243_-|ABC-transporter-ATP-binding-protein
MTSSTSTATRGVAPPPAGRSRDFWGSAARLVKRLAPQRRLSIAVITLGLAGTVIGVIVPRILGHATDLLFNGVIGRQLPAGISKAQAVSAARGRGENTFADLLSGMNVVPGHGVDFGAVARTLTLALALYLVSSVLIWAQARLLNLTVQRTMVALRSDVEDKIHRLPLSYFDGRQRGELLSRVTNDIDNVQSSLSMTISQLLTSVLTVVAVLAMMLSISPLLVGITVLTVPLSLLATRAIARRSQRLFLAQWASIGRLNAHIEETYSGFTVVKTFGHQAAAREQFRALNGDVYRSSFGAQFFSGLVAPATTFIGNVGYVAVAVVGGLRVATGHITLGDIQAFIQYVRQFNSPLSQLAGMYNTLQSGVASAERVFALLDEPEESPDPQPAAPPPADGAPRWTGRVEFAHVSFAYRPGVPVIDDLSLVAEPGSTVAIVGPTGAGKTTLVNLLMRFYEVDSGQILLDGVDIATLDRHSLRSRIGMVLQDTWLFDGTIAQNIAYGRPEAGDGEVVAAAEAAHVDPFVRSLPDGYQTRVSGDGANISAGEKQLITIARAFLARPQLLILDEATSSVDTRTEALIQRAMCDLRRDRTSFIIAHRLSTIRDADRILVIEGGRIVEQGNHAELLARRGAYYAMTRA
>NC_016946.1|WP_009953975.1|1587239_1589006_-|ABC-transporter-ATP-binding-protein
MLLALLRQYIQPYRRLVAMLMVLQLISNLASLYLPTVNAAIIDEGVAKGDTAAIVRLGIVMLGATGLQVLCSVGAVYFGSRTGMGFGRDLRAAVFEHVLTFSERESARFGAPTLLTRSTNDVRQIQYLVQITATVLVTAPIMCLGGIVMALRQEAALTWLLLVSVPVMAVANYWVMSHMLPLFRRMQGLIDGINRVMRDQLAGVRVVRAFAREGFERDRFARANAALSNTALTAGNWQALMLPVTTLTINVSSVALIWFGGQRIDRGQMQVGSLTAFLAYFTQILMAVLMATMTLVVLPRASVCAERITEVLTTRPAVTDPPGPASPPGKITGVVRLDGATFTYPGADRPVLQDISFIARPGTTTAIVGSTGSGKSTLISLMCRLYDVTGGTVLVDDIDVRDYHTELLWSAIGLVPQRGYLFSGTIADNLRYGAAPGHDITGDEMWEALRVADADGFVRAHPDGLQMRVAQGGINFSGGQRQRLAIARAVIRRPAVYLFDDSFGALDVHTDARVRAALKQISKEATVIVVTQRVSTAAQADQVIVIDGGRLVGAGTHESLLADSATYAEFADSQAVGALPSGHVGGAQ
>NC_016946.1|WP_008254722.1|1589187_1589745_+|DUF3558-domain-containing-protein
MRRSARALALVASALTILIPAVAACSDSGGNKPGATASSTPQKGQGNHGPMFPQCGGISDQTVAELTRVTGLINTARNSVGCQWLAGGGILGPHFSFSWYRGSPIGRERKTEELSRASVDDININGHGGFIAVGNEPNLGDSLCEVGIQFQDDFIEWSISFSQKPFPPPCDIAKELARQSIANSK
>NC_016946.1|WP_009953976.1|1589753_1590284_+|DUF3558-domain-containing-protein
MRAAAVVLLAALLVLTGCSRSIGGNAVKAGGNVPRNNNSQQQYPNLLKECEVLTSDILAKTVGADPLDIQSTFVGAICRWQAANPAGLIDITRFWFEQGSLSNERKVAEFLKYKIESRPIAGIDSIVMRPDDANGACGVASDAAGVVGWWVNPQAPGIDACGQAIKLMELTLATNS
>NC_016946.1|WP_009953977.1|1590376_1590880_-|histidine-phosphatase-family-protein
MTAERTLLLMRHAKSDYPAGVADHDRPLAPRGVRQAGLAGDWLRAHVPPVDGVLCSTATRTRETLRNTRIAAPVRYSERLYASTPGTLIDEINTVDDGIGTLLVIGHEPTMSALALGLGRAGGTDAAAAERISAKFPTSAIAVLAVPCAWKELELGGASLIDFVVPR
>NC_016946.1|WP_014379577.1|1591042_1592194_+|exonuclease-SbcCD-subunit-D
MRFLHTADWQLGMTRHFLAGDAQPRYSAARRDAVAGLGALAAEVGAEFVVVSGDVFEHNQLPPTVIGQSLEAMRAIGIPVYLLPGNHDPLDASSVYTSALFAAERPDNVVVLDRAGVHQVRPGLEIVAAPWRSKVPTTDLVADVLDGLPAAAGTRILVAHGGVDVLDPDKDKPSLIRLATLDDALSRGAVHYVALGDKHSLTQVGDSGRVWYSGSPEVTNFDDVESDPGHVLVVDVDETDPRGAVSVTARDVGRWRFVTLHRQVDTSRDIADLDVNLDLMTDKDRTVVRLALTGSLTVTDRAALDACLDKYARLFAWLGLWERHTDLAVIPADGEFSDLGIGGFAAAAVEELVATAREEDSATAVDAQAALALLLRLADRGAA
>NC_016946.1|WP_014379578.1|1592190_1594812_+|AAA-family-ATPase
MKLHRLILTNYRGISHREIEFPDHGVVVVCGANEIGKSSMIEALDLLLESRDRSTKKEVKQVKPTHSDVGSEVSAEISCGPYRFVYRKRFHKKCETELTIITPCREQLTGDEAHERVRAMLAETVDSDLWHAQRVLQSASTAAVDLSGCDALSRALDVAAGDSGGLCGTEPLLIERIDTEYARYFTPTGRPTGQWAAAIARLADAEAAVAECAAAVAEVDDRVARHAVLTEQVADFSQRRIAAGPRVTAAREAADRIAELTAQQREAQLVAAAAAATSAAATAAHTGRLQLLAEIDARAAAVAETEAQAHQAASAHASARAEAEACDATLQRATQVLADLQCRVDAARRRVDRLADLEEADRLSTRLAKVDAIERDRERICAELSTIAVTEELLRRIEDACAAVDRIGDQLASTSAAIEFTAAADIHLVVGGERISLSAGQSWSITAAGSTVVEVSDVLTARVTPGATTLDIHTKHAAAQQEMAAALAAAEVADLAAARSADQRRRELVSARDQLGATLAGLCGDEQIDEMRSRLAQLRAQHPAEPAPGATDIGAARAELDAAQQGHAAASTDCEAHRQAATTAAAALAELSTRATVLQNTLEAQRAELQATAGRLAAERASVSDEELAASADSALRAAQAADQRVGELAAALAAASPDAVAAELAEATKEAESLRERYEEAARALREITIELSVFGSEGRQGKLDAAETEREHAATEHSQIGARARAAKLLRSVMTRHRDTTRRRYVEPYRAELQRLGRPVFGPSFEVDIDSDLCIRSRTLNGITVPYESLSGGAKEQLGILARLAGAALVAKEDAVPVVVDDALGFTDPDRLAKMGQLFDSVGTHGQVIVLTCSPDRYDGVRGAHRIDLTA

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Crispr_ID: NC_016946_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016946_3

2513026-2513110

Unclear

Consensus_repeat	Method
TTAGTGGCGATCGCAAGCGCGGCGTTGCCG	CRISPRCasFinder

1 spacers

cas4

The CRISPR arrays of NC_016946_3

>merge|NC_016946|3|2513026-2513110|CRISPRCasFinder
TTAGTGGCGATCGCAAGCGCGGCGTTGCCGGGCGCAGCGGGTCGCCACCGTCGACTTAGTGGCGATCGCAAGCGCGGCGTTGCCG

>NC_016946|3|3|2513026-2513110|CRISPRCasFinder
TTAGTGGCGATCGCAAGCGCGGCGTTGCCG	GGCGCAGCGGGTCGCCACCGTCGAC
TTAGTGGCGATCGCAAGCGCGGCGTTGCCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_016946.1\|WP_009953386.1\|2509839_2511210_+\|FAD-containing-oxidoreductase	unknown	unknown	gnl\|CDD\|235787
NC_016946.1\|WP_026071592.1\|2509324_2509843_+\|membrane-protein	unknown	unknown	gnl\|CDD\|226432
NC_016946.1\|WP_014380031.1\|2505405_2506269_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376777
NC_016946.1\|WP_008256308.1\|2518749_2520258_+\|pup-deamidase/depupylase	unknown	unknown	gnl\|CDD\|274726
NC_016946.1\|WP_009953392.1\|2503798_2505382_-\|MCE-family-protein	unknown	unknown	gnl\|CDD\|224380
NC_016946.1\|WP_014380036.1\|2521438_2522218_+\|proteasome-subunit-alpha	unknown	unknown	gnl\|CDD\|163403
NC_016946.1\|WP_009953378.1\|2518020_2518626_-\|hypothetical-protein	unknown	unknown	unknown
NC_016946.1\|WP_009953388.1\|2508066_2508348_+\|phosphoribosyl-ATP-diphosphatase	unknown	unknown	gnl\|CDD\|212154
NC_016946.1\|WP_008256314.1\|2522434_2523793_+\|Pup--protein-ligase	unknown	unknown	gnl\|CDD\|274725
NC_016946.1\|WP_008256279.1\|2506270_2507113_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376777
NC_016946.1\|WP_009953385.1\|2511213_2512110_-\|RecB-family-exonuclease	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|225441
NC_016946.1\|WP_009953394.1\|2502746_2503802_-\|MCE-family-protein	unknown	unknown	gnl\|CDD\|273384
NC_016946.1\|WP_008256301.1\|2513114_2513414_-\|DUF503-family-protein	unknown	unknown	gnl\|CDD\|224467
NC_016946.1\|WP_014380032.1\|2507417_2508020_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|188483
NC_016946.1\|WP_009953377.1\|2520375_2520570_+\|ubiquitin-like-protein-Pup	unknown	unknown	gnl\|CDD\|368536
NC_016946.1\|WP_009953381.1\|2513422_2514034_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366517
NC_016946.1\|WP_008256304.1\|2514343_2516173_+\|proteasome-ATPase	unknown	unknown	gnl\|CDD\|200312
NC_016946.1\|WP_009953380.1\|2516207_2518013_+\|hypothetical-protein	unknown	unknown	unknown
NC_016946.1\|WP_029384399.1\|2508350_2509205_+\|ATP-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234781
NC_016946.1\|WP_014380035.1\|2520566_2521442_+\|proteasome-subunit-beta	unknown	unknown	gnl\|CDD\|163402

Protein	Function_ID	Function_description	E-value
NC_016946.1\|WP_009953386.1\|2509839_2511210_+\|FAD-containing-oxidoreductase	gnl\|CDD\|235787	PRK06370, PRK06370, FAD-containing oxidoreductase.	0
NC_016946.1\|WP_026071592.1\|2509324_2509843_+\|membrane-protein	gnl\|CDD\|226432	COG3918, COG3918, Predicted membrane protein [Function unknown].	1.51946e-48
NC_016946.1\|WP_014380031.1\|2505405_2506269_-\|ABC-transporter-permease	gnl\|CDD\|376777	pfam02405, MlaE, Permease MlaE. MlaE is a permease which in E. coli is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane. In NMB1965 it is involved in L-glutamate import into the cell. In Arabidopsis thaliana TGD1 it is involved in lipid transfer within the cell.	1.31619e-60
NC_016946.1\|WP_008256308.1\|2518749_2520258_+\|pup-deamidase/depupylase	gnl\|CDD\|274726	TIGR03688, pupylate_PafA2, proteasome accessory factor PafA2. This protein family is paralogous to (and distinct from) the PafA (proteasome accessory factor) first described in Mycobacterium tuberculosis (see TIGR03686). Members of both this family and TIGR03686 itself tend to cluster with each other, with the ubiquitin analog Pup (TIGR03687) associated with targeting to the proteasome, and with proteasome subunits themselves. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NC_016946.1\|WP_009953392.1\|2503798_2505382_-\|MCE-family-protein	gnl\|CDD\|224380	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism].	7.19746e-21
NC_016946.1\|WP_014380036.1\|2521438_2522218_+\|proteasome-subunit-alpha	gnl\|CDD\|163403	TIGR03691, 20S_bact_alpha, proteasome, alpha subunit, bacterial type. Members of this family are the alpha subunit of the 20S proteasome as found in Actinobacteria such as Mycobacterium, Rhodococcus, and Streptomyces. In most Actinobacteria (an exception is Propionibacterium acnes), the proteasome is accompanied by a system of tagging proteins for degradation with Pup. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	2.3825e-133
NC_016946.1\|WP_009953388.1\|2508066_2508348_+\|phosphoribosyl-ATP-diphosphatase	gnl\|CDD\|212154	cd11547, NTP-PPase_HisE, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Mycobacterium tuberculosis phosphoribosyl-ATP pyrophosphohydrolase (HisE or PRATP-PH) and its bacterial homologs. This family includes M. tuberculosis phosphoribosyl-ATP pyrophosphohydrolase (HisE or PRATP-PH) and its bacterial homologs. M. tuberculosis HisE is encoded by the hisE gene, which is a separate gene presenting in many bacteria and archaea but is fused to hisI in other bacteria, fungi and plants. HisE is responsible for the second step in the histidine-biosynthetic pathway. It can irreversibly hydrolyze phosphoribosyl-ATP (PRATP) to phosphoribosyl-AMP (PRAMP) and pyrophosphate. HisE dimerizes into a four alpha-helix bundle, forming two inferred PRATP active sites on the outer faces. M. tuberculosis HisE has been found to be essential for growth in vitro, thus making it a potential drug target for tuberculosis.	1.94491e-44
NC_016946.1\|WP_008256314.1\|2522434_2523793_+\|Pup--protein-ligase	gnl\|CDD\|274725	TIGR03686, pupylate_PafA, Pup--protein ligase. Members of this family are the Pup--protein ligase PafA (proteasome accessory factor A), a protein shown to regulate steady-state levels of certain proteasome targets in Mycobacterium tuberculosis. Iyer, et al (2008) first suggested that PafA is the ligase for Pup, a ubiquitin analog attached to an epsilon-amino group of a Lys side-chain to direct the target to the proteasome. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NC_016946.1\|WP_008256279.1\|2506270_2507113_-\|ABC-transporter-permease	gnl\|CDD\|376777	pfam02405, MlaE, Permease MlaE. MlaE is a permease which in E. coli is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane. In NMB1965 it is involved in L-glutamate import into the cell. In Arabidopsis thaliana TGD1 it is involved in lipid transfer within the cell.	4.34317e-57
NC_016946.1\|WP_009953385.1\|2511213_2512110_-\|RecB-family-exonuclease	gnl\|CDD\|225441	COG2887, COG2887, RecB family exonuclease [DNA replication, recombination, and repair].	1.92143e-66
NC_016946.1\|WP_009953394.1\|2502746_2503802_-\|MCE-family-protein	gnl\|CDD\|273384	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein. Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis].	5.34088e-40
NC_016946.1\|WP_008256301.1\|2513114_2513414_-\|DUF503-family-protein	gnl\|CDD\|224467	COG1550, COG1550, Uncharacterized protein conserved in bacteria [Function unknown].	9.89293e-38
NC_016946.1\|WP_014380032.1\|2507417_2508020_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	2.71063e-15
NC_016946.1\|WP_009953377.1\|2520375_2520570_+\|ubiquitin-like-protein-Pup	gnl\|CDD\|368536	pfam05639, Pup, Pup-like protein. This family consists of several short bacterial proteins formely known as (DUF797). It was recently shown that Mycobacterium tuberculosis contains a small protein, Pup (Rv2111c), that is covalently conjugated to the e-NH2 groups of lysines on several target proteins (pupylation) such as the malonyl CoA acyl carrier protein (FabD). Pupylation of FabD was shown to result in its recruitment to the mycobacterial proteasome and subsequent degradation analogous to eukaryotic ubiquitin-conjugated proteins. Searches recovered Pup orthologs in all major actinobacteria lineages including the basal bifidobacteria and also sporadically in certain other bacterial lineages. The Pup proteins were all between 50-90 residues in length and a multiple alignment shows that they all contain a conserved motif with a G [EQ] signature at the C-terminus. Thus, all of them are suitable for conjugation via the terminal glutamate or the deamidated glutamine (as shown in the case of the Mycobacterium Pup). The conserved globular core of Pup is predicted to form a bihelical unit with the extreme C-terminal 6-7 residues forming a tail in the extended conformation. Thus, Pup is structurally unrelated to the ubiquitin fold and has convergently evolved the function of protein modifier.	3.82356e-14
NC_016946.1\|WP_009953381.1\|2513422_2514034_-\|hypothetical-protein	gnl\|CDD\|366517	pfam01213, CAP_N, Adenylate cyclase associated (CAP) N terminal.	0.000508138
NC_016946.1\|WP_008256304.1\|2514343_2516173_+\|proteasome-ATPase	gnl\|CDD\|200312	TIGR03689, pup_AAA, proteasome ATPase. In the Actinobacteria, as shown for Mycobacterium tuberculosis, some proteins are modified by ligation between an epsilon-amino group of a lysine side chain and the C-terminal carboxylate of the ubiquitin-like protein Pup. This modification leads to protein degradation by the archaeal-like proteasome found in the Actinobacteria. Members of this protein family belong to the AAA family of ATPases and tend to be clustered with the genes for Pup, the Pup ligase PafA, and structural components of the proteasome. This protein forms hexameric rings with ATPase activity. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NC_016946.1\|WP_029384399.1\|2508350_2509205_+\|ATP-phosphoribosyltransferase	gnl\|CDD\|234781	PRK00489, hisG, ATP phosphoribosyltransferase; Reviewed.	1.58665e-139
NC_016946.1\|WP_014380035.1\|2520566_2521442_+\|proteasome-subunit-beta	gnl\|CDD\|163402	TIGR03690, 20S_bact_beta, proteasome, beta subunit, bacterial type. Members of this family are the beta subunit of the 20S proteasome as found in Actinobacteria such as Mycobacterium, Rhodococcus, and Streptomyces. In Streptomyces, maturation during proteasome assembly was shown to remove a 53-amino acid propeptide. Most of the length of the propeptide is not included in this model. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	7.38136e-129

>NC_016946.1|WP_009953385.1|2511213_2512110_-|RecB-family-exonuclease
MIVQPEAPQSVTGPARQVSRPALSPSRAADFKQCPLLYRFRAIDRLPEAPSPAQLRGSLVHAALQQLYELPAAQRGPDTALSLVQPAWEQVMAATPEMTAGLDPAQRSQLLAEAQALLAGYYRLEDPTRFDPQCCEERVEVELADGTLLRGFIDRIDVAATGELRVVDYKTGKAPPEARALAEFKAMFQMKFYAVALLRSRGVPPTRLRLIYLADGQVLDYSPDHDELLRFEKTLIAIWRAIQSAGQTGDFRPTQSRLCDWCPHQQHCPLFGGTPPPYPGWPESFDPQSDSRSSEPAA
>NC_016946.1|WP_009953386.1|2509839_2511210_+|FAD-containing-oxidoreductase
MTEHFDAIIVGAGQAGPPLAGRLTAAGQRVAIVERKLIGGTCVNTGCIPTKTLVASAHAAHLARRGADYGVGTGEISVDMAKVKARKDEIMLDDRKGVEDWLEGMDGCTVVRGHAVFTDPHTVRVGEDVLHADRIFLNVGGRAVVPDIPGLDEVDFLTNASILELDELPTHLVIVGGSYIALEFAQMYRRFGARVTVVERGPRLASREDEDVSATIEEILRTEDIDIVVDADDVRVTKTDNGFELIPRDGATPIRGSHLLLAAGRRPNTDDLGLPAAGVRTDARGYIVVDDQLKTSVEHIWAMGDCNGKGAFTHTSYNDFEIVAANLLDGDPRRVSDRITTYALYIDPPLGRAGLTVEQVRASGRKALVGKRPMTRVGRAVEKGETQGFMKVVVDAETKEILGAAVFGVGGDEAIHCILDVMSANAPYTTLSRTMHIHPTVSELIPTVLQEMSPLD
>NC_016946.1|WP_026071592.1|2509324_2509843_+|membrane-protein
MTHALVVLLALLIGVVAGLRSLTAPAVVAWAAAPALLGWIDLHGTWASWMASIVAVVVFTVLAVGELINDKLPKTPPRTAAPIFAGRIVMGGLAGAALGAWPHWTFTALGAGVIGAVLGTLGGYQARKRLAAAAGRDLPIALLEDAVAIVGGLVIVAVTGHVLTEYLLTAVK
>NC_016946.1|WP_029384399.1|2508350_2509205_+|ATP-phosphoribosyltransferase
MLRVAVPNKGTLSEPATEILAEAGYRRRTDSKDLTVIDPANQVEFFFLRPKDIAIYVGSGELDFGITGRDLVGDSDAPVRERLALGFGSSSFRYAAPAGRDWKIADLAGKRVATAYPNLVRKDLAGRGIEATVIRLDGAVEISVQLGVADAIADVVGSGRTLSLHNLVAFGDPLCDSEAVLIESDQASHSGTQAARDQLVARIQGVVFGQQYLMLDYDCPRSVVDKATAITPGLESPTIAPLADPDWVAIRALVPRRGVNEIMDELAAIGAKAILASDIRFCRF
>NC_016946.1|WP_009953388.1|2508066_2508348_+|phosphoribosyl-ATP-diphosphatase
MKQSLAVKTFEDLFAELGERARTRPAGSATVAALDGGIHGLGKKILEEAGEVWLAAEHEPDDALAEEISQLLYWTQVLMVARGLSLDDVYRKL
>NC_016946.1|WP_014380032.1|2507417_2508020_+|TetR-family-transcriptional-regulator
MPSANTGSLRDRRRAELLSQIQQTAHQLFAERGFEAVTTEDIASAAGISISTYFRYAPTKEGLLVDPVRDAAAEIVGSYSARPPHESPVEALIQLFVTHARDVSDVDNLDTWRLAVATAPHLLSKSVLISETDHGNLIQQVAHRMGVDAMADIRPALLVHTSLATVQFVLDGWLTSDVGESPPFHEQLEQALRLTLAGFD
>NC_016946.1|WP_008256279.1|2506270_2507113_-|ABC-transporter-permease
MTTAQLDGVVAIRDWSVGYVKRHPVASLTTVGEQFVLGVRTVQYFFVDLITGRFQWHEFVRQGAFMAGTAVLPTILVSLPISVTLSIQFALLAGQVGATSLAGAASGLAVIRQGASLVAAVLMASAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVVPRFAAAVMIGVALTGVVCFAGFFASYMFNVYFQNGAPGSFVSTFASFATTGDMVLALLKAIVFGAIVAIVSSQKGLSTKGGPTGVANSVNAAVVEAILLLMIVNVAISQLYIMLSPRTGL
>NC_016946.1|WP_014380031.1|2505405_2506269_-|ABC-transporter-permease
MTASAYVPFAPISTPLVRLYRRGKVPIIRLGHLLVFFVRAAVAVPLAVRQYSGEFLRLLSNITWGNGSIVVGGGTAGVAVVLGMTVGALVGIEGYNFLDLLGLGPATGFVSSLVNTRELAPLMASLAFAMQGGCRFTAQLGSMRIAEEIDALESIAIRPIPYLVTTRLIASVVAIIPLYAACLAIGYLSTQVVVGIGSGGSTGSYLHYFTLMLAGQDIVYSLIKAVIFVWIASTIQCYYGYYASGGPEGVGVAAGHGMRASITVVIIVNMLLTMALWGVDSGARFGG
>NC_016946.1|WP_009953392.1|2503798_2505382_-|MCE-family-protein
MPNSLELDGRGPSERQLFGVGIAVVVVSALVTAMMLVKSTGRLNDYVRVVADLINVGDGLPQKSDVKYHGVLVGMVNDVVPAAHGEPNYVHIDLKPEYAQAIPAAVTARVVPSNVFAVSSVQLVGSPNQKGPGAKIRQGAHIPEDKQLPTVLFQTTVSKLRDLLAAAGRGRDDRSVGILAALGAATDHRRVSLLNAGAQLNRLLDQLNSIVSTDTGPSTVSALLDATTGLAQTAPDLLDALHQAVEPMRTFAETREQLASLVSGADYTVGTTRQSFDNHIDQLIRITTDFTPVLGVLAQKSNNFVPAVTKLDNLANQFMEQVWNPEKNLGNMHAMLTFTPSSTYTRADCPHYGELKGPSCFTAPLIPVRPDLPEVLLPQNYHPPKDLAPPPGTVIGPDGNLVAVGPPLINPTPNLTDPNPPLAPGITPSPPVPGSANPDNPSPGAPATPQPHQPWVAPVAPKAPWIPQSAFGGSRFGGNVGPVGSQYERNMLGVITGTPASPATELLLGPVARGSTVSLGRPAGEAP
>NC_016946.1|WP_009953394.1|2502746_2503802_-|MCE-family-protein
MKFRGPLIALALFMVVSLTLTWLVYVSLRRDVAGDTARYSAVFTDVYGLREGDDVRMAGVRVGRVEKVELDGKLAKVSFVVQQEQRLFGNTLASVTYQNIVGQRYLGLSLGKEGSPELLAPGSTIPVERTEPSFDVTTLLNGYEPLFSLLNPHDADNLTKGIIQSLQGDTSSLATLVGQTSTLTETFAGRDQALGSVITNLNKVVGNLAAQNDDLDGVITETRSVVGELDRRRPDLVASVGSLARVTGRLSTSASDVYPALREFIDRKPGVARHIMDVEPQVAFFGDNIPLLLKGLVRVGNQGAYGNAYVCDVNFLGFFPGLNDVVPIIINAATPGNRAWHTPRCRSTVDG
>NC_016946.1|WP_008256301.1|2513114_2513414_-|DUF503-family-protein
MWIGWLEFDVLLGDVRSLKQKRSVVRPVVAELQRKFSVSAAETGSHELYRRAGIGVALVSGDRGHAVDVLDAAERLVAAHPEFELLSVRRSLVRPEDLA
>NC_016946.1|WP_009953381.1|2513422_2514034_-|hypothetical-protein
MHRPLSVALSTAIALAVVGLAACSSKHPASESSTVSSLPPATSSQVAAPVTAPLPPPEALTDVLARLADPNVTGDAKVSLVEGATPESAATLDKFTNALRDNGYLPMTFAANDIAWSDKNPSNVKASVAVHTAQADNANFTFPMEFAPFQGGWQLSRHTAETLLALGKSPAAPSSGAPASPPEPAPPPPPPAPEPGPSQNPPG
>NC_016946.1|WP_008256304.1|2514343_2516173_+|proteasome-ATPase
MGSSERSEAFGTPHESDMSSGDEAELEQLRREAAMLREQLEHTVGAQGGARSARDVHQLEARIDSLASRNSKLMETLKEARQQLLALREEVDRLGQPPSGYGVLLGTHEDDTVDVFTSGRKMRLTCSPNIEVALLRKGQTVRLNEALTVVEAGTFESVGEISTLRELLADGHRALVVGHADEERIVWLAEPLVAENLPDGHPDALNDDTRPRKLRPGDSLLVDTKAGYAFERIPKAEVEDLVLEEVPDVSYLDIGGLTRQIEQIRDAVELPFLHKELYREYALRPPKGVLLYGPPGCGKTLIAKAVANSLAKKMAEVRGDDAREAKSYFLNIKGPELLNKFVGETERHIRLIFQRAREKASEGTPVIVFFDEMDSIFRTRGTGVSSDVETTVVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAEAAQDIFSKYLTEELPLHADDLAEFGGDRTACIKAMIEKVVERMYAEIDDNRFLEVTYANGDKEVMYFKDFNSGAMIQNVVDRAKKNAIKSVLETGQPGLRIQHLLDSIVDEFAENEDLPNTTNPDDWARISGKKGERIVYIRTLVTGKSSSASRAIDTESNLGQYL
>NC_016946.1|WP_009953380.1|2516207_2518013_+|hypothetical-protein
MRLRFEAPGDDDAYDQVRGVLLDELDGWWSGVDSDREAVVSDVAVFLDWRYFDSTGVLDDFAPADIAEFLLEWCPRRFEGRPDDAASLCFAVGVYVDFMEATGRLVGGADRAARLRRLADDLAPTLLAEARDPTVVEDLPVPGDAPEPFELPFLYVPPSATDLAAAATAVPLLAKLDALRDYLGPDGKPLTDKGELELADGRALVERLDTGDVLDFELGELKYPARSTAALRRLNFLVQVAIEAGAVDVHRHRVLPGQEWGTRSPVERVESLFAAILLSRPLRSLHSAQLYPEQHVMHDLLDDGIACWLAPLLQDGAKLPFESLLEWVHALVAAQRPSPRWYADEEDTLEAYVEDDMGRLLDVLRQAGVVRWTDALERPQPLGPSNWTGGTVALTALGRHVVPEYLEDAGFALRRLDRINDWDATDLIGAMLLVGKDTHVPLIANWRSDRPAAERVQMVTEAAAAMETAAGRTMGFVALNEFDIDVAEPFVRQLLDSPVAGHAALWLIQRDRADAETLASFVDVAVLVDVLAESLESPEELCSLFAGLSDPSQLLDDIWRHPAPETALVLDALGRHLPDRALAKAARKAAVRHQSWMANRL
>NC_016946.1|WP_009953378.1|2518020_2518626_-|hypothetical-protein
MTDLSGKRYGEVLLVTPGEAGPQATVYNSFPLNDCPAELWSKLDAQAIAKEHGAATALLNGPRYWLMNAIEKQRQGPQITKTFGGIEMIQQATVLLSSMNPAPYTANQVNRHTVFVFNPGEEVYELLDPGGQRWVMQTWSQVADPTLSRADLPGLAARLNLPHGWAYQPRVLTEELRVDTRTRSAHVTQDDLTNSYSLQLD
>NC_016946.1|WP_008256308.1|2518749_2520258_+|pup-deamidase/depupylase
MQRIIGTEVEYGISSPSDPTANPILTSTQAVLAYAAAAGIQRAKRTRWDYEVESPLRDARGFDLSRSAGPPPVVDADEVGAANMILTNGARLYVDHAHPEYSAPECTDPLDAVIWDKAGERVMEAAARHVASVPGAAKLQLYKNNVDGKGASYGSHENYLMSRQTPFSAIIAGLTPFLVSRQVVTGSGRVGIGPSGDEPGFQLSQRSDYIEVEVGLETTLKRGIINTRDEPHADADRYRRLHVIIGDANLAETSTYLKLGTTSLVLDLIEEGPAHGIDLSDLALARPVHAVHAISRDPSLRAAVALADGRELTGLALQRVYLDRVAKLVDSRDPDPRAADIVETWAHVLDQLERDPMECAELLDWPAKLRLLEGFRQRENLSWSAPRLHLVDLQYSDVRLDKGLYNRLVARGSMKRLVSEHQVLEAVDSPPTDTRAYFRGECLRRFGADIAAASWDSVIFDLGGDSLVRIPTLEPLRGSKAHVGALLDSVHSAAELVEQLTS
>NC_016946.1|WP_009953377.1|2520375_2520570_+|ubiquitin-like-protein-Pup
MAQEQTKRGGGGGDEDDFAGSTAAGQERREKLAEETDDLLDEIDDVLEENAEDFVRAYVQKGGQ
>NC_016946.1|WP_014380035.1|2520566_2521442_+|proteasome-subunit-beta
MTWQFSDRLPINSALPGNPAVDLSSFADFLRRQAPELLPASFGAVQSESAGAQLPHGTTIVALKYPGGVVLAGDRRSTQGNMIAGRDVKKVYITDDYTATGIAGTAAIAVEFARLYAVELEHYEKLEGVPLTFAGKVNRLAIMVRGNLAAAMQGLVALPLLVGYDIDAPDPEGAGRIVSFDAAGGWNLEEEGYQSVGSGSIFAKSSMKKLYSQVTDADSAVRVAIEALYDAADDDSATGGPDLVRGIYPTAVTIGPEGALEVPEGRIAELAREVIQSRSRADTFGPDGGEK
>NC_016946.1|WP_014380036.1|2521438_2522218_+|proteasome-subunit-alpha
MSFPYFISPEQAMRERSELARKGIARGKSVVALVYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGESKPPELYRITYDGSIADEPHFVVMGGTTEPITTALKDSYAENANLREATRIAVKALRAGSESSNGDQSTLDVASLEVAILDVDRPRRAFRRINRATLENLLRELDSNGSSDGDGDGDESESNGGSPG
>NC_016946.1|WP_008256314.1|2522434_2523793_+|Pup--protein-ligase
MQRRIMGIETEFGVTCTFHGHRRLSPDEVARYLFRRVVSWGRSSNVFLRNGARLYLDVGSHPEYATAECDSLVQLVTHDRAGEWVLEDLLVDAEQRLADEGIGGDIYLFKNNTDSAGNSYGCHENYLIVRAGEFSRISDVLLPFLVTRQLICGAGKVLQTPKAATFCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAEKYRRLHVIVGDSNMCETTTMLKVGTAALVLEMIEAGVPFRDFSLDNPIRAIREVSHDITGRRPVRLAGGRQASALDIQREYYSRAVEHLQTREPNAQIEQIVDLWGRQLDAVESQDFAKVDTEIDWVIKRKLFQRYQDRYSMELSDPKIAQLDLAYHDIKRGRGVFDLLQRKGLAARVTTDEDIAEAVDNPPQTTRARLRGEFISAAQAAGRDFTVDWVHLKLNDQAQRTVLCKDPFRAVDERVKRLIASM

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Crispr_ID: NC_016946_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016946_4

2540237-2540319

Orphan

Consensus_repeat	Method
AGCTCTACGACGATGCAGCGCGCGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_016946_4

>merge|NC_016946|4|2540237-2540319|CRISPRCasFinder
AGCTCTACGACGATGCAGCGCGCGTAGCGGGGTGCGGAGGAGTAGGGCAATCGGACTGAGCTCTACGACGATGCAGCCCGCGT

>NC_016946|4|4|2540237-2540319|CRISPRCasFinder
AGCTCTACGACGATGCAGCGCGCGT	AGCGGGGTGCGGAGGAGTAGGGCAATCGGACTG
AGCTCTACGACGATGCAGCCCGCGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_016946.1\|WP_014380045.1\|2544534_2545290_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224041
NC_016946.1\|WP_009953355.1\|2536331_2537060_+\|cobalt-precorrin-6A-reductase	unknown	unknown	gnl\|CDD\|236144
NC_016946.1\|WP_009953367.1\|2527239_2530020_+\|RNA-helicase	unknown	unknown	gnl\|CDD\|226947
NC_016946.1\|WP_014380040.1\|2534413_2535580_+\|bifunctional-cobalt-precorrin-7-(C(5))-methyltransferase/cobalt-precorrin-6B-(C(15))-methyltransferase	unknown	unknown	gnl\|CDD\|225151
NC_016946.1\|WP_009953366.1\|2530085_2530847_+\|DUF4333-domain-containing-protein	unknown	unknown	gnl\|CDD\|379513
NC_016946.1\|WP_014380041.1\|2537048_2538410_-\|RNA-polymerase-sigma-factor-SigC	unknown	unknown	gnl\|CDD\|137458
NC_016946.1\|WP_009953345.1\|2547724_2547925_-\|hypothetical-protein	unknown	unknown	unknown
NC_016946.1\|WP_026071593.1\|2545393_2546068_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223477
NC_016946.1\|WP_014380048.1\|2547981_2551557_+\|cobaltochelatase-subunit-CobN	unknown	unknown	gnl\|CDD\|235663
NC_016946.1\|WP_014380039.1\|2533632_2534382_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|235527
NC_016946.1\|WP_014380047.1\|2546170_2547721_+\|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239028
NC_016946.1\|WP_009953361.1\|2532016_2533144_+\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|223085
NC_016946.1\|WP_009953362.1\|2530854_2531811_-\|5'-3'-exonuclease	unknown	unknown	gnl\|CDD\|214682
NC_016946.1\|WP_014380049.1\|2551789_2552170_+\|PPOX-class-F420-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274712
NC_016946.1\|WP_009953356.1\|2535576_2536332_+\|precorrin-4-C(11)-methyltransferase	unknown	unknown	gnl\|CDD\|225430
NC_016946.1\|WP_008256343.1\|2533186_2533597_-\|F420-dependent-biliverdin-reductase	unknown	unknown	gnl\|CDD\|274679
NC_016946.1\|WP_014380043.1\|2542492_2543593_-\|precorrin-3B-synthase	unknown	unknown	gnl\|CDD\|274131
NC_016946.1\|WP_008256356.1\|2541846_2542473_-\|precorrin-8X-methylmutase	unknown	unknown	gnl\|CDD\|181352
NC_016946.1\|WP_014382470.1\|2543695_2544523_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
NC_016946.1\|WP_014380042.1\|2540356_2541850_-\|precorrin-2-C(20)-methyltransferase	unknown	unknown	gnl\|CDD\|381173

Protein	Function_ID	Function_description	E-value
NC_016946.1\|WP_014380045.1\|2544534_2545290_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	5.68992e-92
NC_016946.1\|WP_009953355.1\|2536331_2537060_+\|cobalt-precorrin-6A-reductase	gnl\|CDD\|236144	PRK08057, PRK08057, cobalt-precorrin-6x reductase; Reviewed.	1.01867e-98
NC_016946.1\|WP_009953367.1\|2527239_2530020_+\|RNA-helicase	gnl\|CDD\|226947	COG4581, COG4581, Superfamily II RNA helicase [DNA replication, recombination, and repair].	0
NC_016946.1\|WP_014380040.1\|2534413_2535580_+\|bifunctional-cobalt-precorrin-7-(C(5))-methyltransferase/cobalt-precorrin-6B-(C(15))-methyltransferase	gnl\|CDD\|225151	COG2242, CobL, Precorrin-6B methylase 2 [Coenzyme metabolism].	6.95543e-65
NC_016946.1\|WP_009953366.1\|2530085_2530847_+\|DUF4333-domain-containing-protein	gnl\|CDD\|379513	pfam14230, DUF4333, Domain of unknown function (DUF4333). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 140 and 255 amino acids in length. There are two completely conserved C residues that may be functionally important.	1.20437e-23
NC_016946.1\|WP_014380041.1\|2537048_2538410_-\|RNA-polymerase-sigma-factor-SigC	gnl\|CDD\|137458	PRK09649, PRK09649, RNA polymerase sigma factor SigC; Reviewed.	4.95077e-97
NC_016946.1\|WP_026071593.1\|2545393_2546068_+\|alpha/beta-hydrolase	gnl\|CDD\|223477	COG0400, COG0400, Predicted esterase [General function prediction only].	1.86245e-05
NC_016946.1\|WP_014380048.1\|2547981_2551557_+\|cobaltochelatase-subunit-CobN	gnl\|CDD\|235663	PRK05989, cobN, cobaltochelatase subunit CobN; Reviewed.	0
NC_016946.1\|WP_014380039.1\|2533632_2534382_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|235527	PRK05599, PRK05599, SDR family oxidoreductase.	3.53557e-87
NC_016946.1\|WP_014380047.1\|2546170_2547721_+\|molybdopterin-dependent-oxidoreductase	gnl\|CDD\|239028	cd02110, SO_family_Moco_dimer, Subgroup of sulfite oxidase (SO) family molybdopterin binding domains that contains conserved dimerization domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). .	3.64302e-68
NC_016946.1\|WP_009953361.1\|2532016_2533144_+\|aminopeptidase-P-family-protein	gnl\|CDD\|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	9.12924e-101
NC_016946.1\|WP_009953362.1\|2530854_2531811_-\|5'-3'-exonuclease	gnl\|CDD\|214682	smart00475, 53EXOc, 5'-3' exonuclease.	1.29087e-92
NC_016946.1\|WP_014380049.1\|2551789_2552170_+\|PPOX-class-F420-dependent-oxidoreductase	gnl\|CDD\|274712	TIGR03666, Rv2061_F420, PPOX class probable F420-dependent enzyme, Rv2061 family. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomycetales, make F420. A variant of the Partial Phylogenetic Profiling algorithm, SIMBAL, shows that this protein likely binds F420 in a cleft similar to that in which the homologous enzyme pyridoxamine phosphate oxidase (PPOX) binds FMN. [Unknown function, Enzymes of unknown specificity].	2.4704e-67
NC_016946.1\|WP_009953356.1\|2535576_2536332_+\|precorrin-4-C(11)-methyltransferase	gnl\|CDD\|225430	COG2875, CobM, Precorrin-4 methylase [Coenzyme metabolism].	5.37049e-133
NC_016946.1\|WP_008256343.1\|2533186_2533597_-\|F420-dependent-biliverdin-reductase	gnl\|CDD\|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	6.58286e-28
NC_016946.1\|WP_014380043.1\|2542492_2543593_-\|precorrin-3B-synthase	gnl\|CDD\|274131	TIGR02435, Precorrin-3B_synthase, precorrin-3B synthase. An iron-sulfur protein. An oxygen atom from dioxygen is incorporated into the macrocycle at C-20. In the aerobic cobalamin biosythesis pathway, four enzymes are involved in the conversion of precorrin-3A to precorrin-6A. The first of the four steps is carried out by EC 1.14.13.83, precorrin-3B synthase (CobG), yielding precorrin-3B as the product. This is followed by three methylation reactions, which introduce a methyl group at C-17 (CobJ; EC 2.1.1.131), C-11 (CobM; EC 2.1.1.133) and C-1 (CobF; EC 2.1.1.152) of the macrocycle, giving rise to precorrin-4, precorrin-5 and precorrin-6A, respectively. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	1.81108e-91
NC_016946.1\|WP_008256356.1\|2541846_2542473_-\|precorrin-8X-methylmutase	gnl\|CDD\|181352	PRK08285, cobH, precorrin-8X methylmutase; Reviewed.	1.48692e-120
NC_016946.1\|WP_014382470.1\|2543695_2544523_+\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	7.70433e-74
NC_016946.1\|WP_014380042.1\|2540356_2541850_-\|precorrin-2-C(20)-methyltransferase	gnl\|CDD\|381173	cd11646, Precorrin_3B_C17_MT, Precorrin-3B C(17)-methyltransferase (also named CobJ or CbiH). Precorrin-3B C(17)-methyltransferase participates in the pathway toward the biosynthesis of cobalamin (vitamin B12). There are two distinct cobalamin biosynthetic pathways. The aerobic pathway requires oxygen, and cobalt is inserted late in the pathway; the anaerobic pathway does not require oxygen, and cobalt insertion is the first committed step towards cobalamin synthesis. This model includes CobJ of the aerobic pathway and CbiH of the anaerobic pathway, both as stand-alone enzymes and when CobJ or CbiH form part of bifunctional enzymes, such as in Mycobacterium tuberculosis CobIJ where CobJ fuses with a precorrin-2 C(20)-methyltransferase domain, or Bacillus megaterium CbiH60, where CbiH is fused to a nitrite and sulfite reductase-like domain. In the aerobic pathway, once CobG has generated precorrin-3b, CobJ catalyzes the methylation of precorrin-3b at C-17 to form precorrin-4 (the extruded methylated C-20 fragment is left attached as an acyl group at C-1). In the corresponding anaerobic pathway, CbiH carries out this ring contraction, using cobalt-precorrin-3b as a substrate to generate a tetramethylated delta-lactone.	4.85163e-115

>NC_016946.1|WP_014380041.1|2537048_2538410_-|RNA-polymerase-sigma-factor-SigC
MRCDVAREALSARLDGERPQVLAQQVDAHLESCRSCRSWLIGAAAQTRRFASVAPGEGPDLVDKIMASIDDQASGHPRWMRWLRSHYRRWGLIAVGLFQVAIAAAQISGVDFGMVSGHMHGAMSGEHLMHESTAWLLALGLAMVAAGVWPASASGVAAITGVYSVALLGYVIVDAFDGQVTATRIASHMPLLLGLAFALLVARERVGSHRRHGSDGAVDADYPASAAGPSSGRRRGHLRPINHAAPDHAAPSTTTRRRIGKPAQLRWLSMIAPSDDEAVTELALSAARGNARALEAFIKATQQDVWRFVAYLSDAGNADDLAQETFLRAIGAIERFSGRSSARTWLLSIARRVVADHIRQLQSRPRAALGADPEHVVRGDRNARGFEDLVEVTTMIAGLNPEQREALLLTQLLGLPYADAAAVCGCPVGTIRSRVARARDALLADGERSDLTG
>NC_016946.1|WP_009953355.1|2536331_2537060_+|cobalt-precorrin-6A-reductase
MRVLLLGGTGEARALAKTLHPRVDVISSLAGRVPDPALPVGPVRIGGFGGVDGLRRWLRDEGIDAVVDATHPFAATMTAHAATACGQLRIPHLILARPAWDPGEALVVGSDRHAAQTVARQGYSRIFLTTGRSGVHAFAGSDAWFLIRAVTEPDSASLPRHHRLVLSRGPYRYDEEVALLREHRIDALVTKNSGGQMTRAKLDAAAALEVPVVMVARPPLPEGVTTVGTVADAAEWVGALAG
>NC_016946.1|WP_009953356.1|2535576_2536332_+|precorrin-4-C(11)-methyltransferase
MTVYFIGAGPGAADLITVRGQRLLQTCPVCLYAGSIMPDDLLALCPQDAKIVDTGPLTLEQIIAELREAHAAGHDVARLHSGDPSLYSALAEQCRRLDALGIDYEIVPGVPAFAAAAAALKRELTVPGVAQTVTLTRVATLSTAMPPGEDLATLARSGATLVLHLAAAQIDAIVPQLLDGGYRSETPVAVVAFASWPQETVLRGTLADIAAQMHEANITKTAVILVGDALTAGEFTDSYLYSTGRARGSRH
>NC_016946.1|WP_014380040.1|2534413_2535580_+|bifunctional-cobalt-precorrin-7-(C(5))-methyltransferase/cobalt-precorrin-6B-(C(15))-methyltransferase
MIVVVGIGADGMAGLAEASRAELRRATVIYGSQRQLDLLDDTVPARRREWPSPMLPALEALPVDDDIHVVASGDPLLHGIGGTLIRLHGPEKVRVLPHVSSVTLACARMGWNVHDTEVISLVTAQPHTAVRRGGQAIVLSQGRSTPTELAALLNAHGRGDSQLTVLERLGGPDEHRRDGTARDWAGGAPGHVDDLNVIAVRYLPDERVSPIPDDAFTHDGQITKQGIRAVTLAALAPRPGERLWDVGAASGSIGVEWCLSGPGCGAIAFERDVQRRHNLERNAAAFGVGIEVRGDAPEAFDGAAPPSAIFIGGGLTQPGLLDACLDHLPAGGRLVANVVTTESEAAVTQAYTRLGGELRRFQHYHGKALGAFTGWQPHYPVTQWVMTK
>NC_016946.1|WP_014380039.1|2533632_2534382_+|SDR-family-NAD(P)-dependent-oxidoreductase
MDDTGAGPVLILGGRSEIGVELARRLAPGATVVLAARRADQLADQVSALKAAGAAAVDTREFDADDLASHAALVASVVADHGPIGTAVLAFGILGDQARAETDAAHAVAVVHTDYVAQVSMLTHLATAMRNAGKGRLVVFSSIAGARVRRANYVYASAKAGLDGFANGLADALHGTGVRVLIARPGFVIGRMTEGMTPAPLPSTPAQVAAATARALAKGRRTVWIPWALGPAAAVMRLLPAFVWRRMPR
>NC_016946.1|WP_008256343.1|2533186_2533597_-|F420-dependent-biliverdin-reductase
MANTTTRLTDEALAFLSERHLAMLTTLRADNSPHVVAVGFTFDPRTHIARVITTGGSQKAVNADRGGLAVLSQVDGARWLSLEGRSKVNSDADAVRDAELRYAQRYRTPRPNPRRVVIEVQVERVLGSSDLLDRGA
>NC_016946.1|WP_009953361.1|2532016_2533144_+|aminopeptidase-P-family-protein
MESHRFDAAVYARRLAAAAAAAADAGLAGLVITPGYDLRYLVGSRAQTLERLTALVLPASGDPTVVVPRLELASLKGSAIAELGLAVRDWVDGDNPYDLVGAALGGAPAATAVTDAMPALHLLPLAGVLGALPVLATEVLRMLRMVKEECEVDALRKAGAAIDRVHARVPEFLVPGRTEADVAADIADAIVAEGHSEVAFIIVGSGPHGADPHHGYSDRELQAGDIVVVDIGGTYEPGYNSDSTRTYSIGEPNPEVAEQYSVLQRAQRAAYEAVRPGVTAEQVDAAARDVLAAEGLADYFVHRTGHGIGLSVHEEPYIVAGNDLPLTAGMAFSIEPGIYFPGRWGARIEDIVVVTEDGALAVNNRPHELIVVPVG
>NC_016946.1|WP_009953362.1|2530854_2531811_-|5'-3'-exonuclease
MPGPLVLLDGASMWFRSYFGVPSSITAPDGRPVNAVRGFIDSVAFVITQQRPSRLVVCLDLDWRPQFRVDLVPSYKAHRVAEPEPPGEPDIEEVPDDLTPQIDMIAELLDAFGIPTAGAEGFEADDVLGTLAARERDDPVVVVSGDRDLMQVVSDDPVPVRVLYLGRGLSKATLFGPAEVAEHYGVPVERAGPAYAELALLRGDPSDGLPGVPGVGEKTAASLLAQHGSLEQILAAAHDPKSKMPKGLRAKLLGALDYIEAAGDVVRVATDAHVTFSTAGDELPLVAADPQRTAKLATELGVGSSIARLQKALDALPT
>NC_016946.1|WP_009953366.1|2530085_2530847_+|DUF4333-domain-containing-protein
MSGPQGSDQQWQPPGQGQGSDHSSDPTQVAPSWHDQQTQEASWQAPAYTPPAEYPQYQQPAEQAYPQQYPQQPGYAQPGQYGQPGQYAQPGQYGQPGQYPQPGQYGQPGQYPPPGQYGQYGQYGQPGQYPPQYPPYEQPGKKRPVGLIAGVGGGIALLLVVVVLVLGFWQPGFFVTTKLDVSKAQAGVQQVLSDETNGYGAKNVKDVKCNHGQNPTVKKGATFDCDVSIDGAPKHVTVTFQDNKGTYEVGRPQ
>NC_016946.1|WP_009953367.1|2527239_2530020_+|RNA-helicase
MAELVELTRFATDLPFALDGFQHRACAALERGHGVLVCAPTGAGKTVVGEFAVHLALAAGGKCFYTTPLKALSNQKHTDLTARYGRDRIGLLTGDMSVNADAPVVVMTTEVLRNMLYADSPALRGLSYVVMDEVHFLADRMRGPVWEEVILHLPDEVRVVSLSATVSNAEEFGGWIQTVRGDTTVVVDEHRPVPLWQHVLVGKRLFDLFDYRHSDAPEQPGAPREPRVNPDLLRHITHRREADRMSDWQPRRSAGRGRPPARSGRPRLYRTPARPDVIASLDAEGLLPAITFVFSRAGCDAAVQQCLRSPLQLTTQEERAQIAEVIEHRCGDLADADLAVLGYYEWREGLLRGLAAHHAGMLPAFRHTVEELFTAGLVRAVFATETLALGINMPARTVVLERLVKFNGEQHVALTPGEYTQLTGRAGRRGIDVEGHAVVLWNPTEETTEPSAVAGLASTRTFPLRSSFAPSYNMTINLVQQMGPEQAHRLLEQSFAQYQADRSVVGLVRGIERGDAMLGEIAGELGGPKAPILEYARMRARISEMERAQSRASRLQRRQAASDALAALRRGDIINITHGRRGGLAVVLESARDSSDPRPLVLTENRWAGRISSADYSGMSAPVGSMPLPKRVEHRQPRVRRDLASTLRSAAAGLAIPAKRRGRGDADGEFHDPELAKLREQLRRHPSHNTPGREEQVRQAERYLRIERDNAQLEKKVAAATNSLARTFDRIVGLLTERGFIEGRDGDPRVTDDGRLLARIYSESDLLVAECLRTGAWSGLKPAELAAVVSSVLYESRGGDGPGAAFAADAPTQPLRQALQQTSRLSMALRADEQTHRIAPSREPDDGFVNVIYRWARTGDLAAALAAADPAGSGSPLLAGDFVRWCRQALDLLDQVRNAAPDAEVRATAKRAINDIRRGVVAVDAG
>NC_016946.1|WP_014380042.1|2540356_2541850_-|precorrin-2-C(20)-methyltransferase
MTARGTLWGVGLGPGDPELVTVKAARVIGEADVVAYHSARHGRSIARGIAERYLRPGQIEEHLVYPVTTEVTDHPGGYAGALEDFYAEATERIAAHLDAGRNVALLAEGDPLFYSSYMHLHTRLTERFDAVIVPGVTSVSAASAAIATPLVAGDEVLSVLPGTLPVAELTRRLADADAAVVLKLGRSYHAVREALSASGQLDDTFYVERASSAGQRILPAAEVDETSVPYFSLAMLPGGRRLHRRAPEGQATGSVAVVGLGPGDADWMTPQSRRELAAATDLIGYGGYLDRVPVHEGQQRHPSDNRDEPERARLACALAEQGRAVAVVSSGDPGVFAMATAVLEEAKQWPGVQIRVIPAMTAAQAVASRVGAPLGHDYAVISLSDRLKPWEVISARLEAAAAADLVLAIYNPASKTRTLQVGAMRDILLAHREPGTPVVIGRNVSGDDEDVRVVRLADLNPAEIDMRCLLIVGSSQTQWYSADSAEDRVFTPRRYQP
>NC_016946.1|WP_008256356.1|2541846_2542473_-|precorrin-8X-methylmutase
MLDYIRDAAEIYRQSFATIRAEADLARFPADVARVVVRLIHTCGQVDVAEHVAFTDDVVERVGAALRGGAPVLCDSSMVAAGITTARLPAGNEVVSLVADPRAAELAARRQTTRSAAGVELWAERLDGAVLAIGNAPTALFRLLELIDEGLAPPAGVLGGPVGFVGSAQSKQELVDRPRGMSYLVVQGRRGGSAMAAAAVNAIASDAE
>NC_016946.1|WP_014380043.1|2542492_2543593_-|precorrin-3B-synthase
MARTRDTDACPGALQVHQAADGALARVRLPGGMLTAAQLAALSAAATQSGSGTLELTARGNVQLRGLTDVTAVAETLAAAGLLPSTTHERVRNIVASPLSGRAGGDVDVRGWVGDLDAATCAAPRLADLGGRFWFSLDDGRADVSGLRADIGVHASPDGCALLLAGRDTGVRLAPGEVVETLVALATRFVEIRETAWRVQELADLRRLLPDAEPGGTPFPVVTKAPVGWIGQDDGRVTLGAAVPLGVLPARVAEYLAAIEAPLVITPWRSVLVCDLQESVADTALRVLAPLGLVFDENSPWLTVSACTGSPGCAHSAADVRADAAQALDADVTQHRHFVGCERACGSPPAGQVLVATGDGYRMLRT
>NC_016946.1|WP_014382470.1|2543695_2544523_+|ABC-transporter-permease
MSIATALDAAPKQPRSAQTGAPGGLWARRKWEIVRIASPLALLALWQLGSAVGVIPQDVLPAPSLIVEAGVELIRDGQLAAALQVSSVRVVEGLVLGGVIGVGAGAAVGLSRWLEATVDPPMQMIRALPHLGLIPLFILWFGIGELPKVLLVALGVVFPLYLNTFSAIRQVDPKMVETAQVLGFSFAQRFTRILVPSAAPQVLVGFRQSLAIAWLTLIVAEQINADKGIGFLINNARDFLRIDIIIFGLTIYALLGIVTDAIVRLIERRALRYRH
>NC_016946.1|WP_014380045.1|2544534_2545290_+|ABC-transporter-ATP-binding-protein
MTVIAESDAHPRVRTEVAGELRHVDKWYGNRHVLKDVSVRVRGGEIVALVGRSGSGKSTVLRVLAGLSRDHSGERVVAGAPALAFQEPRLFPWRDVRTNVGYGLTRSRLPRPQVRQRAERALADVGLTDHAGSWPLTLSGGQAQRVSLARALVAEPRLLLLDEPFGALDALTRLTMHALLLDLWRRHGFGVLLITHDVDEAVALADRVLVLEDGRIIHTVTIDEPRRTPGHPGAHTERHRAELLDRLGVQS
>NC_016946.1|WP_026071593.1|2545393_2546068_+|alpha/beta-hydrolase
MDTVEYAPGRLADVFGDSRRPTVLLWHGMQTDARAAFGPLAGMLSDRGAAVVAPDWNSHADDGGRADLLGSLDFTRDFAGPGNGIVLVGWSMGGCAAAGLTLNPARFDAALVHTVCLAGAFMAPDPLSGQAPTDALSDGRAGTPFTLLHGLADDAVPVSASREFAAALGRVGWPVELVELDADHGSIAGADYDPVADRYGPGTSEEALRVAGEVATRISALIGH
>NC_016946.1|WP_014380047.1|2546170_2547721_+|molybdopterin-dependent-oxidoreductase
MTSVAAASSNDRMIAGVAAASVALGVTQLASIPFGARAEPRAAVGSAVVDLTPGPVKEWAIQTLGPLDKPFLAVVLLVVIAAIAAIAGTLETRRRPFGSVVIAAAGVLGCIAVLSRPGGTALDTLPTIVGAACGVGVLRVLARRFSPEPDDDADDQELAHPSRRRLVMYGLLGLGVVSGVVGAFGTRLAHSVEADRKTFALPRPRSPARPIPAEVQPKGVALPSFITSSADFYRVDTALSVPQLSRGDWRLRIHGMVDREITLSFDDLARFDIVETVTTLTCVSNPVGGDLISTGIWTGYRLAELLATAGVHLDADMVLSTSIEGFTVGTPVQAVTDGRDALLAVGLNGQPLPAEHGYPARMVVPGLYGYVSATKWVVDLELTRFDRAKAYWTRQGWAAQAPIKTESRIDVPRGGQTVPVGPVVFGGVAWAQNRGVRAVEVRIGDGGWQPAELGASYSNETWRLWRFPWQAKSPGRETITVRAIDNTGAVQTEERANPVPDGATGWHTVNFAVVPA
>NC_016946.1|WP_009953345.1|2547724_2547925_-|hypothetical-protein
MSRGFVVTFAVGLIVALFGVIWALQGFGVLGGSPMSNTTTWSVIGPITALVGIAIAVISWRKLSSK
>NC_016946.1|WP_014380048.1|2547981_2551557_+|cobaltochelatase-subunit-CobN
MAEPTILLLSTSDTDLISARSSGKNYRWANPSRLSEDDLPDLLAGVAIVVVRILGGYRAWQGGIDTVIASGVPTVLVSGEQAADAELTGLSTLAAGIAVQAHIYLAHGGVDNLRQLHAFLSDTVLMTGFGFTPPVVTPTWGELARPNAKDVDGPTIAVLYYRAQHLAGNTGYVESLCGAIEDAGARPLPVYCASLRTAEPELLQRLSAADAMVVTVLAAGGLKPATASAGGDDDSWNVEHLAALDIPILQGLCLTSPRAQWCENDDGLSPLDVASQVAVPEFDGRIITVPFSFKEIDEDGLISYVADAERCARVAGLAVRHAQLRHVTPPDKRVALVFSAYPTKHARIGNAVGLDTPASAVALLRAMRDRGYHVGDLPGVEANDGDALIHALIERGGQDPDWLTEGQLAGNPIRVSATDYRAWFATLPAEFTDAVVQHWGPPPGELFVARSNDPDGEIVIAAIKSDNVVLMVQPPRGFGENPVAIYHDPDLPPSHHYLAAYRWLDTGFGAHAVVHLGKHGNLEWLPGKTLGMSAGCAPDAALGNLPLIYPFLVNDPGEGTQAKRRAHAVLVDHLIPPMARAETYGDIARLEQLLDEHANVAALDPGKLPAIRQQIWTLIRAAKMDHDLGLTERPAEDSFDDMLLHVDGWLCEIKDVQIRDGLHILGQKPTGEPELDLVLAILRARQLFGGEHAIPGLRQALGLAEDGTDERTSVDATETVARELVAALQASGWDPDAADGLSDNPEVARVLRFAATEVVPRLAGSSAEIEQVLRALDGRFIPAGPSGSPLRGLVNVLPTGRNFYSVDPKAVPSRLAWEAGVALADSLLARYRDDHGRWPRSVGLSVWGTSAMRTAGDDIAEVLALLGVRPVWDDASRRVVDLAPIPLAELGRPRIDVTVRISGFFRDAFPHVVTMLDDAVRLVAGLDEPAEDNFVRAHAQADLAQHGDQRRSTTRIFGSKPGTYGAGLLQLIDSRNWRDDADLAAVYTAWGGFAYGRDLDGREAVDDMNRQYRRIAVAAKNTDTREHDIADSDDYFQYHGGMVATVRALTGQAPAAYIGDNTRPDAIRTRTLSEETTRVFRARVINPRWMAAMRRHGYKGAFEMAATVDYLFGYDATAQVMADWMYEQLTERYVLDPENRKFMAESNPWALHGMAERLLEAAGRGMWAQPQPETLDGLRRALLESEGDLEG
>NC_016946.1|WP_014380049.1|2551789_2552170_+|PPOX-class-F420-dependent-oxidoreductase
MTPTFADLAKAQYILLTTFTKDGRPKPTPIWVAADQGRLLVITQEQSWKVKRIRNTPRVTLATCTMNGRPTSDAVEGTAVILDKSHTAAVYDAIGKRYGIVGKVFNFFSKLRGGMENNVGLELKVA

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Crispr_ID: NC_016946_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016946_5

4221935-4222021

Orphan

Consensus_repeat	Method
CGCTGCGCGGAATGCATCGTCGCCGGGCTAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_016946_5

>merge|NC_016946|5|4221935-4222021|CRISPRCasFinder
CGCTGCGCGGAATGCATCGTCGCCGGGCTACCCCGAGCGCCCACTCCTCCGCATCCCGCTGCGCGGAATGCATCGTCGCCGGGCTAC

>NC_016946|5|5|4221935-4222021|CRISPRCasFinder
CGCTGCGCGGAATGCATCGTCGCCGGGCTAC	CCCGAGCGCCCACTCCTCCGCATCC
CGCTGCGCGGAATGCATCGTCGCCGGGCTAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_016946.1\|WP_008259653.1\|4223229_4224300_-\|potassium-channel-family-protein	unknown	unknown	gnl\|CDD\|367001
NC_016946.1\|WP_026071234.1\|4211201_4214180_-\|UPF0182-family-protein	unknown	unknown	gnl\|CDD\|234609
NC_016946.1\|WP_162130200.1\|4215382_4216759_+\|zinc-dependent-metalloprotease	unknown	unknown	gnl\|CDD\|227607
NC_016946.1\|WP_008259652.1\|4222297_4223230_-\|NAD(+)-diphosphatase	unknown	unknown	gnl\|CDD\|234699
NC_016946.1\|WP_014380918.1\|4233251_4234439_-\|adenylyltransferase/sulfurtransferase-MoeZ	unknown	unknown	gnl\|CDD\|181156
NC_016946.1\|WP_008259632.1\|4219095_4219347_-\|WhiB-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376791
NC_016946.1\|WP_008259667.1\|4232361_4233216_-\|TIGR02569-family-protein	unknown	unknown	gnl\|CDD\|131620
NC_016946.1\|WP_009955776.1\|4214253_4215276_-\|PDZ-domain-containing-protein	unknown	unknown	gnl\|CDD\|226011
NC_016946.1\|WP_036459570.1\|4222032_4222287_+\|mycoredoxin-Mrx1	unknown	unknown	gnl\|CDD\|131255
NC_016946.1\|WP_014380917.1\|4230905_4231142_+\|hypothetical-protein	unknown	unknown	unknown
NC_016946.1\|WP_014380909.1\|4209465_4210116_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|188314
NC_016946.1\|WP_009955654.1\|4231187_4231976_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_016946.1\|WP_009955799.1\|4219751_4221851_-\|ATP-dependent-DNA-helicase-UvrD2	unknown	unknown	gnl\|CDD\|223288
NC_016946.1\|WP_009956596.1\|4210217_4211198_+\|GlxA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|227311
NC_016946.1\|WP_009955653.1\|4231978_4232287_+\|MGMT-family-protein	unknown	unknown	gnl\|CDD\|226219
NC_016946.1\|WP_014380916.1\|4227692_4230818_-\|ATP-dependent-helicase	unknown	unknown	gnl\|CDD\|223288
NC_016946.1\|WP_014380908.1\|4208747_4209446_-\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|376405
NC_016946.1\|WP_008259631.1\|4217742_4219086_+\|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl\|CDD\|223733
NC_016946.1\|WP_014380915.1\|4224348_4227696_-\|ATP-dependent-helicase	unknown	unknown	gnl\|CDD\|223288
NC_016946.1\|WP_179300182.1\|4216845_4217661_+\|cyclodehydratase	unknown	unknown	gnl\|CDD\|274832

Protein	Function_ID	Function_description	E-value
NC_016946.1\|WP_008259653.1\|4223229_4224300_-\|potassium-channel-family-protein	gnl\|CDD\|367001	pfam02254, TrkA_N, TrkA-N domain. This domain is found in a wide variety of proteins. These protein include potassium channels, phosphoesterases, and various other transporters. This domain binds to NAD.	9.10223e-24
NC_016946.1\|WP_026071234.1\|4211201_4214180_-\|UPF0182-family-protein	gnl\|CDD\|234609	PRK00068, PRK00068, hypothetical protein; Validated.	0
NC_016946.1\|WP_162130200.1\|4215382_4216759_+\|zinc-dependent-metalloprotease	gnl\|CDD\|227607	COG5282, COG5282, Uncharacterized conserved protein [Function unknown].	1.1219e-160
NC_016946.1\|WP_008259652.1\|4222297_4223230_-\|NAD(+)-diphosphatase	gnl\|CDD\|234699	PRK00241, nudC, NAD(+) diphosphatase.	2.08982e-124
NC_016946.1\|WP_008259632.1\|4219095_4219347_-\|WhiB-family-transcriptional-regulator	gnl\|CDD\|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	3.93046e-14
NC_016946.1\|WP_008259667.1\|4232361_4233216_-\|TIGR02569-family-protein	gnl\|CDD\|131620	TIGR02569, conserved_hypothetical_protein, TIGR02569 family protein. This protein family is found, so far, only in Actinobacteria, including as least five species of Mycobacterium, three of Corynebacterium, and Nocardia farcinica, always in a single copy per genome. The function is unknown. [Hypothetical proteins, Conserved].	4.73137e-135
NC_016946.1\|WP_009955776.1\|4214253_4215276_-\|PDZ-domain-containing-protein	gnl\|CDD\|226011	COG3480, SdrC, Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms].	2.9985e-141
NC_016946.1\|WP_036459570.1\|4222032_4222287_+\|mycoredoxin-Mrx1	gnl\|CDD\|131255	TIGR02200, conserved_hypothetical_protein, Glutaredoxin-like protein. This family of glutaredoxin-like proteins is limited to the Actinobacteria and contains the conserved CxxC motif.	5.30263e-42
NC_016946.1\|WP_014380918.1\|4233251_4234439_-\|adenylyltransferase/sulfurtransferase-MoeZ	gnl\|CDD\|181156	PRK07878, PRK07878, molybdopterin biosynthesis-like protein MoeZ; Validated.	0
NC_016946.1\|WP_014380909.1\|4209465_4210116_-\|HD-domain-containing-protein	gnl\|CDD\|188314	TIGR03401, Uncharacterized_protein_YFL061W/YNL335W, HD domain protein, cyanamide hydratase family. Members of this protein family are known, so far, in the Ascomycota, a branch of the Fungi, and contain an HD domain (pfam01966), found typically in various metal-dependent phosphohydrolases. The only characterized member of this family, from the soil fungus Myrothecium verrucaria, is cyanamide hydratase (EC 4.2.1.69), a zinc-containing homohexamer that adds water to the fertilizer cyanamide (NCNH2), a nitrile compound, to produce urea (NH2-CO-NH2). Homologs are likely to be nitrile hydratases.	1.55704e-14
NC_016946.1\|WP_009955654.1\|4231187_4231976_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.42193e-15
NC_016946.1\|WP_009955799.1\|4219751_4221851_-\|ATP-dependent-DNA-helicase-UvrD2	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	4.63319e-124
NC_016946.1\|WP_009956596.1\|4210217_4211198_+\|GlxA-family-transcriptional-regulator	gnl\|CDD\|227311	COG4977, COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription].	7.33429e-88
NC_016946.1\|WP_009955653.1\|4231978_4232287_+\|MGMT-family-protein	gnl\|CDD\|226219	COG3695, COG3695, Predicted methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair].	3.05033e-29
NC_016946.1\|WP_014380916.1\|4227692_4230818_-\|ATP-dependent-helicase	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	3.20768e-69
NC_016946.1\|WP_014380908.1\|4208747_4209446_-\|nitroreductase-family-protein	gnl\|CDD\|376405	pfam00881, Nitroreductase, Nitroreductase family. The nitroreductase family comprises a group of FMN- or FAD-dependent and NAD(P)H-dependent enzymes able to metabolize nitrosubstituted compounds.	3.05961e-20
NC_016946.1\|WP_008259631.1\|4217742_4219086_+\|AarF/ABC1/UbiB-kinase-family-protein	gnl\|CDD\|223733	COG0661, AarF, Predicted unusual protein kinase [General function prediction only].	3.1123e-124
NC_016946.1\|WP_014380915.1\|4224348_4227696_-\|ATP-dependent-helicase	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	7.82825e-109
NC_016946.1\|WP_179300182.1\|4216845_4217661_+\|cyclodehydratase	gnl\|CDD\|274832	TIGR03882, hypothetical_protein, bacteriocin biosynthesis cyclodehydratase domain. This model describes a ThiF-like domain of a fusion protein found in clusters associated with the production of TOMMs (thiazole/oxazole-modified microcins), small bacteriocins with characteristic heterocycle modifications. This domain is presumed to act as a cyclodehydratase, as do members of the SagC family modeled by TIGR03603.	0.00117316

>NC_016946.1|WP_009955799.1|4219751_4221851_-|ATP-dependent-DNA-helicase-UvrD2
MPTVADPLTAGLDDEQREAVLAPRGPVCVLAGAGTGKTRTITHRIAQLVAGGHVAAGQVLAVTFTQRAAGEMRSRLRAIDAAAGTGPAVGAVSALTFHAAAHRQLRYFWPRVVGDTGWQLLDSKFAVVARAASRTRLNASTDDVRDLAGEIEWAKASLIGPEEYPAAVAAAGRDIPLDAAQIAGVYAAYEALKARGEHVTLLDFDDLLLHTAAAIENDPAVAEEFRDRYRCFVVDEYQDVTPLQQRVLTAWLGDRDDLTVVGDANQTIYSFTGASPRFLLDFSRRFPDATVVRLERDYRSTPQVVSLANQVIAAARGRVAGSKLHLVGQRPPGPAPTFHEHPDEPAEAAAVAASIARLIESGTPPSEIAVLYRVNAQSEIYEEALTEAGIAYQVRGGEGFFNRQEIKQALLALHRAAERGAEGPLPDVVRAVLEPLGLTAQEPVGTRARERWEALSALAELVDDEVAQRPQLDFPGLLAELRMRADARHPPVVQGVALASLHAAKGLEWDAVFLVGLADGTLPISHALAHGAESEAVEEERRLLYVGITRARTHLALTWALARSPGGRQGRKPSRFLNGIAPQARAEPGPNKSRRNRATATRCRICNNNLTTPAAVMLRRCETCAADIDEDLLLRLKAWRLDVAKEQKVPAYVVFTDNTLIAIAELRPDDDEALIAIPGIGARKLEQYGPDVLELVRGR
>NC_016946.1|WP_008259632.1|4219095_4219347_-|WhiB-family-transcriptional-regulator
MSARIAPRPDLPCHAGDPDLWFAEAPADLERAKSLCVDCPVRRQCLAAALERAEPWGVWGGEIFDRGSVLSFKRPRGRPRKAA
>NC_016946.1|WP_008259631.1|4217742_4219086_+|AarF/ABC1/UbiB-kinase-family-protein
MDDGYVADIKRGRAARNAKLASIPVGFAGRAALGFGKRLTGKSRDEVQAELLEKAAHQLFTVLGELKGGAMKVGQALSVLEAAIPEEFGEPYREALTKLQKDAPPLPAAKVHRVLDAQLGTKWRERFSSFDDTPVASASIGQVHKGVWSDGREVAVKIQYPGADEALRADLKTMQRLVGVFKQLAPGADIQGVVDELIERTEMELDYRLEAENQRAFAKAYHDHPHFAVPRIVASAPKVVIQEWMQGIPMAEIIRHGTTEQRDLVGTRLLELTFDAPRRLEMLHGDAHPGNFMLLDDGRMGVIDFGAVAPLPGGLPIELGMSIRLARDKNYDLLLPTMEKAGFIQKGQQVSVRDIDDMLRQYVEPVEVEVFHYTRKWLQKMSAIEIDRSVSQIRTARQMDLPPKLVIPMRVIMSVAAILCQLDAHVPIKALSEELVPGFAEPDNAVV
>NC_016946.1|WP_179300182.1|4216845_4217661_+|cyclodehydratase
MPVLLRPDGAVQVGWDPRRAVLVRPPGGLAAAELATLLRTMSSPTPLPELQRRALDRGLTDTEGLRSLVAQLVRAGVATECGRPRGRAPSVRVHGRGPLSELLVESLRCSGARIAHSSQPHAAVSAGDVDLVVLSDYLVADPRMVRDLHDQGVAHLLVRVRDGIGLVGPLVIPGVTSCLGCADLHRSDRDAAWPAICAQLRETVGVADRATVLATAALALSQVNRVIAAVRGQGAASEPEPPQTLNATLEFDLHAGAIVARQWVKHPLCAC
>NC_016946.1|WP_162130200.1|4215382_4216759_+|zinc-dependent-metalloprotease
MSTVGVMADLPFGFSPGEDPDKHGKKDPDSGSNPSDPFAAFGMSGDFGMGDLGQIFTQLGQMFSSAGTVGPGGTASGPVNYELARRVASNSIGFVAPVPDTTNSAIADAVHLAETWLDGATALPAGTAKAVGWTPADWVDNTLATWKRLCDPMAQQISTVWAASLPEEAKSMAGPLLQMMSQMGGMAFGSQLGQALGRLSREVLTSTDIGLPLGPKGIAAIMPDAVESFTTGLERPRSEILTFLAAREAAHHRLFSHVPWLSSQLLGAVEAYAMGMQIDMSGIEELARDFNPASLSDPAAIENLLGQGVFEPKATPAQTQALERLETLLALIEGWVQVVVAAALGDRIPGAGALGETLRRRRASGGPAEQTFATLVGLELRPRKMREAAAFWERLTQAAGVDTRDGIWQHPDLLPNAEDLDEPAGFIDRVIGGDTSGIDEAIAKLEREDPDSDGPVDN
>NC_016946.1|WP_009955776.1|4214253_4215276_-|PDZ-domain-containing-protein
MNRRILTLMVALVPIVVFGVLLAVVTVPFVSLGPGPTFDTLGEVDGKQVVAIQGTLTHPTTGHLNMTTVSQRDDLTLGEALTLWLSDTEQLVPRDIIYPPGKSREEVDKANSADFKQSEDSAEYAALGYLKYPSAVTVAKVPEPGPSAGKLKAGDAIDAVNGTPVATVDAFTGLLKNTKPGQTVTIDYRRKNEPAGVAQITLGSNKDRDYGYLGVAVLDAPWAPFVVDFNLANIGGPSAGLMFSLAVVDKLTTGGLAGSNFIAGTGTITADGKVGQIGGITHKMVAAHAAGATVFLVPAKNCYEASSDNPSGLRLVKVETLSQAVDALHAITSGGQPPSC
>NC_016946.1|WP_026071234.1|4211201_4214180_-|UPF0182-family-protein
MGMRPTARMPKLTRRSRILILIALGVIALLLAGPRLIDAYVDWLWFGELGYRSVFSTVLVTRFVVFLIAGLLVGGIVFAGLAVAYRTRPVFVPSNDNDPVARYRALVLSRLRLVSAGVPVAIGLLAGIIAQSYWVRIQLFLHGGDFGIKDPQFGKDLGFYAFELPFYRLLLSYLFVAVFLAFVANLLAHYIFGGIRLSGRTGALSRSARIQLVTLVGLLVLLKAVAYWLDRYELLSHTRGGKPFTGAGYTDINAVLPAKLILMAIALICAGAVFSAVVLRDLRIPAIGLVLLLLSSLIVGAGWPLIVEQISVKPNAAQKESEYISRSIAATRQAYGLTADVVTYRNYTGDAQATAQQVADDRATTSNIRLLDPTIVSPAFTQFQQGKNFYYFPDQLSIDRYLDRNGSLRDYVVAARELNPDRLIDNQRDWINRHSVYTHGNGFIASPANTVRGIANDPNQNGGYPEFLVNVVGANGNVVSDGPAPLDQPRVYYGPVISNTAADYAIVGRNGADREYDYETSNETKNYTYTGLGGVPLGDWLSRSVFAAKFAERNFLFSNVIGSNSKILFNRDPARRVEAVAPWLTTDSAVYPAIVNKRLVWIIDGYTTLDNYPYSELTSLESATADSNEVAFNRLAPDKRVSYIRNSVKATVDAYDGTVSLYQQDEQDPVLKAWMRVFPGTVKPKSDITPELAEHLRYPEDLFKVQRMLLAKYHVNDPVTFFSTSDFWDVPLDPNPTASSYQPPYYIVAKNIAKNDNSSSYQLTSAMNRFKRDYLAAYISASSDPATYGRITVLTIPGQVNGPKLANNAITTDPAVSQDLGVIGRDNQNRIRWGNLLTLPVGQGGLLYVEPVYASPGASDAASSYPRLIRVAMMYNDKIGYGPTVRDALTGLFGPGAGAAATGIQPTEAGTPANPPPSAPAPAATPGSPPPAAVPPAPDGSVALSPAKAAVLQEIQAAIGAAKDAQKKGDFAGYGAALQRLDDAITKYNNTK
>NC_016946.1|WP_009956596.1|4210217_4211198_+|GlxA-family-transcriptional-regulator
MADVAHEGKHSRVVVIVVFDGVTLLDVAGAGEVFVEANRFGADYRLKIASVDGRDVTSSIGTRLGVTDRLSAIDSADIVLVAGSDHLPGRPIDPALVEAVRSVAARTGRMASICTGSFILAQAGLLDGRRATTHWHDARLLARAFRDVTVEPDAIFVRDGDVFTSAGISSGIDLALALVEMDHGTELVRDVARWLVVYLKRAGGQSQFSVLVEADPPPQSPLRAVTEAVAADPGADYSVKKLAALASLSTRQLTRLFQSELGMTPARYVELVRVDFARNALEAGRSVTETAGMAGFGSIETLRRAFVNHLGISPKAYRDRFRTAYA
>NC_016946.1|WP_014380909.1|4209465_4210116_-|HD-domain-containing-protein
MTTSSIDAIAGIHVPDTALAREVTDFIRDTEDELLFNHSRRVFFFGALQGLRRGIHPNLELLYAAAMFHDVGLTDHYRNSTVRFEVDGANAARDFLMDAGADKADADIVWLGIALHTTPGVPEFLAPEVALLQAGVEVDVVGVGREQLAPEALAAVTAAHPRPDFKNRILAAFNDGMKHRPHSTAGTMNADVLAHFDPKFERVDFVDKILHNSWPE
>NC_016946.1|WP_014380908.1|4208747_4209446_-|nitroreductase-family-protein
MDIHEALYTTRMMRRLRPDPVPLDTQARILDAAIRAPNGANTQRWHFVAVDDPALIGEFAQLFRRARALEYEKFGAGTGPMVAPAPGADAAAHAETMRRIKGSGDYLADHFEEIPLLLFVFAIDDLGGANIFPAIWSVLLAARAEGVGGVMTMVLRNFEDRVNELLGVPVEEGWTMSAMLALGYPRGKWGVAANRHPVHEVSSRNGWNTPFGVEVPQPLWPPQDTASLPAAG
>NC_016946.1|WP_036459570.1|4222032_4222287_+|mycoredoxin-Mrx1
MTTAPLTVYTTSWCGYCHRLMTVLKSNGIPYETVDIEHDAAAADFVSSVNGGNRTVPTVKFADGSTLTNPSAAQVKAKLAETGS
>NC_016946.1|WP_008259652.1|4222297_4223230_-|NAD(+)-diphosphatase
MAIADFQLRSVPLLSRVGADRADQLRTDVEAATAGWAEAALLRVDSRNQVLVSDGRVVLGAAAELGDKPPSEAVFLGRLEGGRHVWAIRGALQAPEDPDARTEVVNLRSLGPIFDDTSGQLMSSAVALLNWHEKSRFSSVDGSPTRPARAGWSRVNPVTGHEEFPRIDPAVICLVHDGGDRAVLARQAVWPERMFSLLAGFVEAGESFEGCVAREIREEIGLTVRDVRYLGSQPWPFPRSLMVGFHAVGDPAQDFSFNDGEIAEAAWFTRDEVREALAAGDWSSSSESKLLLPGSISIARVIIESWAAID
>NC_016946.1|WP_008259653.1|4223229_4224300_-|potassium-channel-family-protein
MGNGRSRKLSGLDETLTAQRGHQLIGVVRIPEEHASPIRVITRRLAIALVVLFGAAVIVYLDRDGFRDVRNEPLTFLDCLYFSAVSLSTTGYGDITPYTETARLVHTLIFTALRIAFLAVLVGTTLEVLSERSRQGWKIQRWRSRVRNHTIVIGYGTKGKTAVAAILGDETIQAEVVVVDTDRSTLEHAESAGLVTVHGDATKADVLRLAGAQHAASIIVATSRDDTAVLATLTAREIAPNAKIVASIREAENQHLLQQSGADSVVVSSATAGRLLGLATTTPSVVEMIEDLLTPDAGLAIAEREVEQSEVGGSPRHLRDIVLGVVRDGHLWRIDAPEVDAVEANDRLLYIRSVGH
>NC_016946.1|WP_014380915.1|4224348_4227696_-|ATP-dependent-helicase
MNARYNPSELACALGLFPPTEEQSAVIAAPPGPLVVIAGAGAGKTETMAARVVWLIANGYAEPAQVLGLTFTRKAAGQLLRRVRSRLARLAGVGLGPVGDAAAEPEGAPVISTYHAFAGSLLRDYGLLLPVEPDTRLLSETELWQLAFDVVNGYRGELHTDKTPAAVTSMVLRLWGQLAEHLVDTGQLRDTHVELERLVHGLPAGPYQRERGPSQWLLRLLGTQTERAELVPLLDALDERMRAEKVMDFGMQMASAARLAAGFPQVGEDLRARYRVVLLDEYQDTGHAQRIALSALFGGGVDDGLALTAVGDPIQSIYGWRGASATNLPRFTTDFPRSDGTPAPVLELRTSWRNPPRTLRVANAVSAEARRRSVAVHALRPRPDAPPGTVRCALLPDVVAEREWIADHLDAHYRRARVEGVSPPTAAVLVRRNADAAPIADALRARGIPVEVVGLAGLLSVPEVAEVVAMLRLVADPTAGAAAMRVLTGARWRLGARDIAALWQRARALGGTAGDPAPPSPEAIARAADPSHVDADTVCLADAIADPGPAGSYSAAGYQRITALGAELSALRAHLGHPLADLVAEVRRVLGVDCEVRAAAGVAAGWAGTEHLDAFADVVAGYAERADGAATRLDASATASVAGLLGFLDAAEAVENGLAPAPLAVARDRVQVLTVHSAKGLEWEVVAVAHLSGGTFPSTASRSTWLTDAAELPPLLRGDRAAAGALGIPVLDTSDVTNRKQLSDKISEHRRQLDQRRVDEERRLLYVAITRAEDTLLVSGHHWGATGVKPRGPSDFLVEIKDVIDRAAAAGDPCGTVEHWAPSPADGERNPLRDNVIEAVWPADPLAVRREEVERGATLVRRALAAGPGRPCADVDGWAADVDALLAERARLIEPPVRELPGQLSVSSLVGLARDPAGTAQRLRHRLPSRPDPHALLGNAFHSWVQKFYGAECLFDLGDLPGAADSDVGDSAELAALQAAFTESPWAARTPVAVEVPFEMPIGETLVRGRIDAVFADPDGGATVVDWKTGEPPHGAEALRQAAVQLAVYRMAWAALAGVAESSVRTAFYYVRAGTTVVPDELPSAAELAGLLIDPDGTRCDPRRPSIGEAVPVVT
>NC_016946.1|WP_014380916.1|4227692_4230818_-|ATP-dependent-helicase
MAHTWEADASAVLAPGARGIVRVLGGPGTGKSSLLIDAAVTRIDAGIDPESVLLLTGSGRLGMAERSALTTALLRSRPGRVVVSEPLVRTVHGYAYAVLRRAAERAGDAPPRLVTSAEQDAIIRELLAGDLDDGPRATSAWPAQLRAALSTAGFATELRNLLARCAERGIDPGELERLGRRCRRPEWIAAGQFARQYEQVMLLRAAVGTAAPEATTPALGAAELVGAALEAFAVDPELLAAERGRIRVLLVDDVQQLDSQAARLVRVLAAGAELALIAGDPNQAVFGFRGGEPAGLLDGDGPAVTLTTSHRCAPAVARAVSGIAARLPGGGAGRRIDGAGAGEGSVTVRLAASAHAEAAAIADALRRAHLVDGVPWSQMAVIVRSVPRAGARLPRALAAAGVPVAAAAATGPLAEEPAVRALLTVLLAAADGLDGQQALALLTGPIGRVDPVSLRQLRRTLQRANPDRPPGDFAELLAETLSGAVPPGPQFRSLRKVRAVLDAAARCHEAGEDPRYTLWAAWHRSGLQRRWLSVSERGGPATAQATRDLESVTALFDITDDYVSRTSGASLRGLVEHVAALHLPNANPEPAATAGQVRVLSAHAALGHEWDFVVIAGLQDGLWPNTVPRGGVLGTQRLLDELDGVTADASMRAPLVAEERRLLVAAMGRARRRLLVTAVDSDTGGADHAAALPSPFFFDIAQWADEDVETTALQPVAAPRVLSAAALVGRLRGVVCAPDGAVDELARDCAATQLARLAKAGVPGADPAGWHGLTPVSTGEPLRGGGDVVTLTPSTLQTLTDCPLRWLAERHGGTNPRDLRSTIGSVVHALIAEPHRSESGLLAELERAWQHLPFAAQWHSDNELARHRAMLEAFVEWRSQSRGALTEVGVEVEIDGTLQTGDGEQVRLRGRVDRLERDAAGRLVIVDVKTGKSPVSKDDAQQHAQLAMYQLAVSEGLVAPGGDTVEPGGARLVYVGKAGAAGAVEREQDPLTADAGDEWRQVIRRAAAATAGPQFVARRNDGCTHCPIRPCCPAHTDGAAR
>NC_016946.1|WP_014380917.1|4230905_4231142_+|hypothetical-protein
MVSRLQKEGLTTMTDEHGFPIDEAPEGDAVEQLRPADSEDDAGLDTDYVSARDREANEADVIEQAYVVSADDDRDDDR
>NC_016946.1|WP_009955654.1|4231187_4231976_+|alpha/beta-hydrolase
MTAKLYVHRYGPSGPARILALHGLTGHGQRWQHLSGLLPEIGLAAPDLLGHGRSSWAAPWTIDANVSALAALLDAQPGTPVVVVGHSFGAGLAMHLAAARPNQVSGLLLLDPAIGLDGAWMREIAEAMLSSPDYPDAEEARLEKVHGSWSDVEPALLEAELDEHLVALPNGRYGWRISLPAMMAYWSELARDAVLPPAQTPTILVRAKRTSPPYVTDELIAGLAAQRLGSRFRLLDFDCNHMVPYAKPDDVAALARELLEAR
>NC_016946.1|WP_009955653.1|4231978_4232287_+|MGMT-family-protein
MAPVTDDQVERVRALVAAIPSGRVATYGDIASVAGLSSPRIVGWIMRTDSSDLPWHRVITASGRPARHLTTRQLELLRAEGVLARDGRIALGEVRYEFPDGA
>NC_016946.1|WP_008259667.1|4232361_4233216_-|TIGR02569-family-protein
MTVEPPPDHVLSAFGLAGVKPVYLGASWEGGWRCGEVVLSLVADNARAAWSARVRETLFVDGVRLARPVRSTDGRYVVSGWRADTFVAGTPEPRHDEVVSAAVRLHEATGKLERPRFLTQGPAAPWGDVDIFIAADRAAWEERPLASVPPGARVAPATADAERSVELLNQLATLRKPTKSPNQLVHGDLYGTVLFVGTAAPGITDITPYWRPASWAAGVAVIDALSWGEADDGLIERWNALPEWPQMLLRALMFRLAVHALHPRSTAEAFPGLARTAALVRLVL
>NC_016946.1|WP_014380918.1|4233251_4234439_-|adenylyltransferase/sulfurtransferase-MoeZ
MLSVSSLPPLVAPADHLTGDEVARYSRHLIIPGLGVDGQKRLKNARVLVIGAGGLGAPTLLYLAAAGVGTIGIVEFDVVEESNLHRQIIHGVADVGRPKAVSARESMLAINPLVDVRLHEVRLDSTNAVELFSCYDLIVDGTDNFATRYLINDAAVLAKKPYVWGSIYQFEGQISVCWEDAPDGRGLNYRDLYPEPPPPGTVPSCAEGGVLGIVCASIASVMSTEVIKLITGIGDSLLGRLMIYDALQMTYRTIAIRRDPSDASRPKITELVDYEQLCGATADTPAGDATAITPRELRELLDSGKELALIDVREPVEFDIVHIEGAQLVPQSSINSGEGLAKLPRDRMPVLYCKTGVRSAQALAVLKQAGFADAVHLEGGIVAWAQQMQPDMILY

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Crispr_ID: NC_016946_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016946_6

4806459-4806602

Orphan

Consensus_repeat	Method
GGTGAAACCAGGGCGGGAAAATCGCGAAAAGCTCGCCGTGAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_016946_6

>merge|NC_016946|6|4806459-4806602|CRISPRCasFinder
GGTGAAACCAGGGCGGGAAAATCGCGAAAAGCTCGCCGTGAGCTCACACCCAAAGCCCTGAGCTCACACTCGATGCCGCGGCGCGGCGGCCTACCCGCCGAAGGTGAAACCAGGGCGGGAAAATCGCGAAAAGCCCGCCGTGAG

>NC_016946|6|6|4806459-4806602|CRISPRCasFinder
GGTGAAACCAGGGCGGGAAAATCGCGAAAAGCTCGCCGTGAG	CTCACACCCAAAGCCCTGAGCTCACACTCGATGCCGCGGCGCGGCGGCCTACCCGCCGAA
GGTGAAACCAGGGCGGGAAAATCGCGAAAAGCCCGCCGTGAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_016946.1\|WP_008261313.1\|4806674_4808300_-\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NC_016946.1\|WP_008261301.1\|4801625_4801997_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319923
NC_016946.1\|WP_014381253.1\|4808475_4809168_-\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|376349
NC_016946.1\|WP_014381248.1\|4798479_4800222_+\|cytochrome-c-biogenesis-protein-DipZ	unknown	unknown	gnl\|CDD\|239310
NC_016946.1\|WP_014381250.1\|4802044_4803775_+\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|226179
NC_016946.1\|WP_014381254.1\|4810388_4811447_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|235337
NC_016946.1\|WP_085976859.1\|4797680_4798367_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|375435
NC_016946.1\|WP_014381249.1\|4800231_4801086_-\|hypothetical-protein	unknown	unknown	unknown
NC_016946.1\|WP_008261321.1\|4809676_4810243_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380054
NC_016946.1\|WP_009953511.1\|4801096_4801615_-\|mycothiol-transferase	unknown	unknown	gnl\|CDD\|368218
NC_016946.1\|WP_179293530.1\|4814974_4815697_+\|phosphatidylserine-decarboxylase	unknown	unknown	gnl\|CDD\|235400
NC_016946.1\|WP_008261338.1\|4815693_4816554_+\|CDP-diacylglycerol--serine-O-phosphatidyltransferase	unknown	unknown	gnl\|CDD\|224104
NC_016946.1\|WP_008261325.1\|4811489_4812440_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|235737
NC_016946.1\|WP_008261318.1\|4809197_4809689_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380345
NC_016946.1\|WP_009953506.1\|4805005_4805569_+\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|367130
NC_016946.1\|WP_014381252.1\|4805557_4806382_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223377
NC_016946.1\|WP_044059249.1\|4813691_4814909_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340951
NC_016946.1\|WP_014381251.1\|4803814_4804459_+\|PPE-family-protein	unknown	unknown	gnl\|CDD\|366325
NC_016946.1\|WP_008261307.1\|4804497_4804899_+\|hypothetical-protein	unknown	unknown	unknown
NC_016946.1\|WP_014381256.1\|4812459_4813665_+\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452

Protein	Function_ID	Function_description	E-value
NC_016946.1\|WP_008261313.1\|4806674_4808300_-\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NC_016946.1\|WP_008261301.1\|4801625_4801997_-\|VOC-family-protein	gnl\|CDD\|319923	cd07262, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	3.75378e-41
NC_016946.1\|WP_014381253.1\|4808475_4809168_-\|aminopeptidase-P-family-protein	gnl\|CDD\|376349	pfam00557, Peptidase_M24, Metallopeptidase family M24. This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.	1.03483e-18
NC_016946.1\|WP_014381248.1\|4798479_4800222_+\|cytochrome-c-biogenesis-protein-DipZ	gnl\|CDD\|239310	cd03012, TlpA_like_DipZ_like, TlpA-like family, DipZ-like subfamily; composed uncharacterized proteins containing a TlpA-like TRX domain. Some members show domain architectures similar to that of E. coli DipZ protein (also known as DsbD). The only eukaryotic members of the TlpA family belong to this subfamily. TlpA is a disulfide reductase known to have a crucial role in the biogenesis of cytochrome aa3.	1.54318e-64
NC_016946.1\|WP_014381250.1\|4802044_4803775_+\|amidohydrolase-family-protein	gnl\|CDD\|226179	COG3653, COG3653, N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism].	4.49712e-129
NC_016946.1\|WP_085976859.1\|4797680_4798367_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|375435	pfam17929, TetR_C_34, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in putative TetR family transcriptional regulators found in bacteria.	2.61072e-21
NC_016946.1\|WP_008261321.1\|4809676_4810243_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|380054	pfam17920, TetR_C_16, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. This entry represents the C-terminal domain found in a number of different TetR transcription regulator proteins found in Actinobacteria. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain.	1.66457e-22
NC_016946.1\|WP_009953511.1\|4801096_4801615_-\|mycothiol-transferase	gnl\|CDD\|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	4.1642e-24
NC_016946.1\|WP_179293530.1\|4814974_4815697_+\|phosphatidylserine-decarboxylase	gnl\|CDD\|235400	PRK05305, PRK05305, phosphatidylserine decarboxylase family protein.	7.19973e-103
NC_016946.1\|WP_008261338.1\|4815693_4816554_+\|CDP-diacylglycerol--serine-O-phosphatidyltransferase	gnl\|CDD\|224104	COG1183, PssA, Phosphatidylserine synthase [Lipid metabolism].	2.87047e-70
NC_016946.1\|WP_008261325.1\|4811489_4812440_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|235737	PRK06197, PRK06197, short chain dehydrogenase; Provisional.	0
NC_016946.1\|WP_008261318.1\|4809197_4809689_+\|cupin-domain-containing-protein	gnl\|CDD\|380345	cd02215, cupin_QDO_N_C, quercetinase, N- and C-terminal cupin domains. This family contains quercetinase (also known as quercetin 2,3-dioxygenase, 2,3QD, QDO and YxaG; EC 1.13.11.24), a mononuclear copper-dependent dioxygenase that catalyzes the cleavage of the flavonol quercetin (5,7,3',4'-tetrahydroxyflavonol) heterocyclic ring to produce 2-protocatechuoyl-phloroglucinol carboxylic acid and carbon monoxide. Bacillus subtilis quercetin 2,3-dioxygenase (QDO) is a homodimer that shows oxygenase activity with several divalent metals such as Mn2+, Co2+, Fe2+, and Cu2+, although the preferred one appears to be Mn2+. The dioxygen binds to the metal ion of the Cu-QDO-quercetin complex, yielding a Cu2+-superoxo quercetin radical intermediate, which then forms a Cu2+-alkylperoxo complex which then evolves into endoperoxide intermediate that decomposes to the product. Quercetinase is a bicupin with two tandem cupin beta-barrel domains, both of which are included in this alignment model. The pirins, which also belong to the cupin domain family, have been shown to catalyze a reaction involving quercetin and may have a function similar to that of quercetinase.	1.97239e-18
NC_016946.1\|WP_009953506.1\|4805005_4805569_+\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|367130	pfam02627, CMD, Carboxymuconolactone decarboxylase family. Carboxymuconolactone decarboxylase (CMD) EC:4.1.1.44 is involved in protocatechuate catabolism. In some bacteria a gene fusion event leads to expression of CMD with a hydrolase involved in the same pathway. In these bifunctional proteins CMD represents the C-terminal domain, pfam00561 represents the N-terminal domain.	2.62093e-05
NC_016946.1\|WP_014381252.1\|4805557_4806382_-\|SDR-family-oxidoreductase	gnl\|CDD\|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	8.36501e-92
NC_016946.1\|WP_044059249.1\|4813691_4814909_-\|MFS-transporter	gnl\|CDD\|340951	cd17393, MFS_MosC_like, Membrane protein MosC and similar proteins of the Major Facilitator Superfamily of transporters. The gene encoding Sinorhizobium meliloti membrane protein MosC is part of the mos locus, which encodes the biosynthesis of the rhizopine 3-O-methyl-scyllo-inosamine. MosC belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.5036e-73
NC_016946.1\|WP_014381251.1\|4803814_4804459_+\|PPE-family-protein	gnl\|CDD\|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.02807e-52
NC_016946.1\|WP_014381254.1\|4810388_4811447_+\|alpha/beta-hydrolase	gnl\|CDD\|235337	PRK05077, frsA, esterase FrsA.	9.08651e-08
NC_016946.1\|WP_014381256.1\|4812459_4813665_+\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	9.39262e-154

>NC_016946.1|WP_014381252.1|4805557_4806382_-|SDR-family-oxidoreductase
MALPAPSPTSTAVVTGASSGIGADIARELADRGHGLTLVARREDRLRDLADELAGRVRVEVIACDVADSAARAGLFDEVERRGLTADILVNNAGIGTMGSVTKIPVADEIAQVRVNVEAVIDLSTRAVQRMVPRGRGAILNVGSTAGYQPFPGQAGYAATKAFVNNYTHGLRGELAGTGVTVALLCPGPVRTEFVKSAGMDEREFADAFPKFMWKPSREVARAGVDALESDRPTVIPGLPSQISTRLFQFMPRRVLLPLLKNQHPSLRRDRSAG
>NC_016946.1|WP_009953506.1|4805005_4805569_+|carboxymuconolactone-decarboxylase-family-protein
MSRIAPLAPPWSEEDAAGINSWGHPDRTYEPLLLVRCLQRHPVLASRLRKLGESLYTAALLPPRTRTIAILRICALLRCAYEWGGQAAFWGPIAGVSDDECDALVLAGADDPRWGPAERTLIAAVDECERTGSWSEATWEALGDFLDDEQRIELLTAVGWYRTICTLCNALALPVEGWMRPWPGSAG
>NC_016946.1|WP_008261307.1|4804497_4804899_+|hypothetical-protein
MRSKKKVDFAALADALVDYPYAYLITVDDEYRSHTVTVEPELRGQTLEVGLIGGRTQQNLARRRDVTLLWPPAEPGGYSLIVDGAAEVSPEGGAGDAVRLTVTPTRALLHRDADSPDAARGCLHDCVVFSLPA
>NC_016946.1|WP_014381251.1|4803814_4804459_+|PPE-family-protein
MTNPHFAWLPPEVNSALIFSGPGPGPLLAAAAAWDGLAGELASSASSFSSVTSDLASGSWQGASSAAMMTVASQYVSWLSAAAAQAEEVSHQASAIATAFEVALAATVQPAVVAANRALVRALAANNHLGQNTPAIADIEAAYDQMWASDVAAMFGYHADASAAVAKLPPWNEVLQNLGFSNTTTAVTRPASSGAVARGYTSRIAGFLTPPAPQ
>NC_016946.1|WP_014381250.1|4802044_4803775_+|amidohydrolase-family-protein
MTCDLIIRNGTIVDGLGGEPYVGDVAVTDNVIKAVGDVNGAAANREIDATGLLVTPGFVDLHTHYDGQSIWSERLTPSSAHGVTTVVMGNCGVGFAPCRQSDHDVLVDVMAGVEDIPGVVMTDGLPWTWETFPEYMDALDAGKRDIDVAAYLPHSPLRVYVMGQRGADREPATEDDLAKMRALAKEAIEAGALGFASSRLTIHKTESGSPIPSYDAAREEIEQIARGVVDGGGGLLQFVPDIPAGGYQPVLQTVFDVAEDVGLPLTFTLVVANSGDPSWPDAITMIEKANAAGGDITAQLLPRPIGLIIGLQLSANPFVLYPSYREIAHLPLAERVAEMRKPEVRARILADKPGQGHPILYVAQMWDWIYPLGEDPDYEPDPSTSIGARARAKGVEPMEEAYDRLLDDDGKAMLLVATSNLQGNSLDTVGELLHRDDVVLGLGDGGAHYGMICDASYSTYFLTHWARDRKAGRFTVPEAVRELTSVPARIAGLSDRGRIAVGYKADLNVIDHAALRLHKPVITYDLPAGGRRLDQTADGYVATIVSGEIIAEHGVPTAARPGKLVRGRQPAPAPLQ
>NC_016946.1|WP_008261301.1|4801625_4801997_-|VOC-family-protein
MIDHVGINCADYAKSQRFYDAVLETLGFSRQLDVGPAIGYGRGGKPTFWISGALAGPNREVHLAFEAPDEDAVRAFYRVAVELGAEPLHEPRLWPEYHPGYFGAFVRDPDGNNVEAVFHGALP
>NC_016946.1|WP_009953511.1|4801096_4801615_-|mycothiol-transferase
MARTDDAAVIQDLLRDAFTRLIEHVDEITEGLTEEVSSYRPTPDANSIAWLLWHSARVQDLQLADVAGVEQVWLRDGWVDRFGLDLPQGDMGYGHSPDDVAKVKAPADLLSGYYHAVHELTLEYLGGITAEELARVVDTNWDPPVTASARLVSIIDDCAQHLGQAAYVRGIA
>NC_016946.1|WP_014381249.1|4800231_4801086_-|hypothetical-protein
MRFAASVLLWLITTLALAVAIPAAWTQLHVVDADGYAALARGAAADPDLQSAMAAELTTRAMALIAEHGGGRYPVDSSDVHDAASAFTAGPAFPPLFAQANRAAHGWLFGDPGGGENGDQWAVDVAPMLGDDSIRPLLSRYNVTVPAKLAVPLTVSMPQAMRQGRLSRLSTWGPWVSVGAAALCGVCALLTLAAARRRGKALSSLGVSALLVGAAGWAGLEVAGRYVDKALNRTTGDIRRVAEAMVGHAEAGVHQWLNVTLLAGAALVGLGVVVAMVGSLWKKS
>NC_016946.1|WP_014381248.1|4798479_4800222_+|cytochrome-c-biogenesis-protein-DipZ
MQTIALIGFLGGLITGISPCILPVLPVILLSGAGGTRADSRRVSSVSRPYLVIAGLVCSFSLATLLGSALLTALHLPQDAIRWAALVVLTLIGLGLIFPPVQHLIERPFAYLPQRQIGANADGFGLGLTLGALYVPCAGPVLAAIVVAGGTSSIGPGALVLTATFALGNAVPLLAFALAGRRVAERVAAFRRRQRAIQIAGGIAMIVLAAALVFNLPAMLQRAVPDYTTAMQNKLGANDIGHSLNPTPAQQPNRGTGLALSPPSVTVEGALSDCSSGSDELQQCGPAPALTGVTGWLNTPDGKPLDPAEVRGKVVLIDFWAYSCINCQRAIPHVIDWYNRYHDAGFVVIGVHTPEYAFERVPENVASGAADLHIPYPIALDNDYATWNNFHNVYWPAEYLIDANGQVRHTKFGEGDYDGTEKLIRQLLADAHPGAPLPAPTSSADTTPQTRLTPETYLGVERSGNYGGTGDYTSGTVTLSFPPTLADDTFALRGRWTLDDQGATAEGDDATVRLNYTAKDVYAVVGGTGTLTVTRDGTTTTTPIGGAPTLHRIVADDSAHRDQLDMRVSKGLQVFSFTFG
>NC_016946.1|WP_085976859.1|4797680_4798367_-|TetR/AcrR-family-transcriptional-regulator
MRYALPVAQLTFQRARTEEKKRQRAEALVEAARSLAMETGVASVTLTAVASRAGIHYSAVRRYFTSHKEVLLRLSAEGWVRWSNTVSDKLAEPGAKSPSRIAGTLAEALADDPLFCDLLANLHLHLEHEVDAERVIEVRRISTAATRSLADAIERALPELGRSGSLDILLAAYSLAATLWQVANPPADLTDVYAEEPEVAPPEWNLDFATALTRLLTATCIGLIAEAA
>NC_016946.1|WP_008261313.1|4806674_4808300_-|chaperonin-GroEL
MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETKDQIAATAAISAGDQSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISGYFVTDAERQEAVLEDPFILLVSSKVSTVKDLLPLLEKVIQAGKPLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVISEEVGLSLESADVALLGKARKVVVTKDETTIVEGAGDSDAIAGRVAQIRSEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALLHATPSLDELKLTGDEATGANIVRVALEAPLKQIAFNGGLEPGVVAEKVRNSPAGTGLNAATGEYEDLLKAGVADPVKVTRSALQNAASIAGLFLTTEAVVADKPEKAAAPVGDPTGGMGGMDF
>NC_016946.1|WP_014381253.1|4808475_4809168_-|aminopeptidase-P-family-protein
MEAAEELRVERLLDAERKAAQLFDEIERRAMIRSGVGEKELSDEIHDLAGEMFGVTRHWHRRIVRAGENTLQPFHERPPDRLIVDDDIVFLDLGPIFEEWEADFGRTFLLGDDPHKRAVRDALPRVWQAGRDYFAGNPDVTGAELFDFVVGAAHAEGFEWASRIAGHLVGEFPHKKIAGPGIEWYIMPGSDKPMRRTDPRGRICHWILEIHLVDRPRGFGGFYEQLLDLP
>NC_016946.1|WP_008261318.1|4809197_4809689_+|cupin-domain-containing-protein
MSLVVPPYPPARYTAEEPEISAWLKRADQPPDYETSGVKYHYLANQQDTAGDYGLYRVDIAPAGGGPPAHFHRAMSEAFFVLSGTMKLYDGTEWADGHQGDFLYVPPGGVHGFRNEADEPASILMLFAPGAPREAYFEGFAALADMTDEERREWFVRHDNYWV
>NC_016946.1|WP_008261321.1|4809676_4810243_-|TetR-family-transcriptional-regulator
MLAARIAAAARDEFAVHGWAGTTIRAVARRADVDPALVYHYFGSKEGLLDAATNPPQQWLDRVAEVWATPVERLGAALLQLLLASWADDEIGPTLRAILQTAAHDPATRDKLRRVVEGSLMGVSGLGSDDRDRLIRSGLISSQMMGFALMRYVWKIEPVASMTDDEAIAAIAPNLQRYVDGDLGGQTQ
>NC_016946.1|WP_014381254.1|4810388_4811447_+|alpha/beta-hydrolase
MYTYDIDAAAMFDDRTDQFAKFGVPLEDIERVRSAVDDMWDDAPGGWVYEWSRVARDYAERGDHRMASLVYGCAKFPCLTDAARVKALQHQLEQFQLAANGFPVHFERRIVAVGYRGGSVEVPVHLYSADGRYADRAVLIASGGVDTWKMDIHPWWVGFTQGAGVTTLAFDHPGTGETDIPLDEHADEVIRGLIGYARTLGDGRVAHFGASFGGNFAAMSGLTGIVDAAIELGGPVVDAFAVENIAKLPYGMRDIVGNAMHWDHSPTLEELSAGLSRLNRRDLLARQGNSEMLVINGADDYFVPQSDTLVFQGRPDTEVHLIEGTGHVAMSKAPEVVPRVIAWLRAQMTTER
>NC_016946.1|WP_008261325.1|4811489_4812440_+|SDR-family-NAD(P)-dependent-oxidoreductase
MASNDKETRAWSESDVPDQSGRVVVITGANTGIGYEAAAVLAHRGAHVVLAVRNLEKGNAALSRIVAAGGQGSREVDVTLQQLDLTSLDAVRSAADALRAAYPRIDLLINNAGVMWTPKQVTADGFELQFGTNHLGHFALTGLLLDHLLPVRDSRVVTISSLGHRLRAAIHFDDLQWEHRYDRIAAYGQSKLANLLFTYELQRRLAATPDAKTIAVAAHPGGSNTELTRNLPAIFRPAAAALGPVLFQSAAMGALPTLRAATDPDVQGGQYFGPDGFLEQRGHPKLVKSSAQSHDAELQRRLWAVSEELTGVRFPV
>NC_016946.1|WP_014381256.1|4812459_4813665_+|molybdopterin-molybdotransferase-MoeA
MRSVAEHQRVVTDLIRPRPPVSVALTDAQGLVLAEDVIAQLALPVFDNSAMDGYAVRAEDTASATPENPVVLPVAEDIPAGRTDELTLQPGTAHRIMTGAPLPAGATAIVPVEATDGGVDVVSIREPREAGKHIRCAGEDVAPGTTVLRRGQVVTPAVLGLAAALGIAELPVIPRQRVLVISTGSELVTPGVPLRPGQIYESNSIMLAGAVRDAGADLVAVATAEDDVAQFSSIIDRYAADSDLIITSGGVSAGAYEVVKDAFGREGDQGVEFVKVAMQPGMPQGVGRVAGATIVTLPGNPVSALVSFEVFIRPALRTAMGLPDPERPHRSAVLAESLTSPRGKRQFRRAVLSDDASSVTSYGPPASHHLRWLASANGLLDIPEDVVEVPEGTRLQVWDLR
>NC_016946.1|WP_044059249.1|4813691_4814909_-|MFS-transporter
MQPHSADRRATPVRRAKRGVTAAFIAHGLVFSSWAAHIPRVKDELGLSDAALGTALFGAPLGSVVATLASHWALRRWGSHRLIPVMAAGYAVAGTTVGLAKSGAALFGALALWGTFQGALDVAMNTQAATVERAARAPIMARFHGMWSVGTLVGAVIGAACVGAGIGLTAQLTVLGAVVLIVVGMLTRRLIPDAADDSDASSGPTPQGRRAWMTPTVAILAAVSFASFLCEGAATDWSANYLRNVVGAGPSVSALSYAAYTLTMVITRFGAPRLHARVPSRRLLPALAVVAVAGMSVTLATANAAVGVLGFAALGVGVALLVPTAFSAAYGASEAGSAIAIVAATGWLGYLLGPPLIGHLSGWVGLSAALATIPVMMSIVGIAIRYNPAFDKADEFHRDVATPAG
>NC_016946.1|WP_179293530.1|4814974_4815697_+|phosphatidylserine-decarboxylase
MARRPRTIGPTASDPGFSPQHALELVRSAVPPVHPAGRPFIGAGLALALAGRRHRWVRRAGLLAAGACAGFFRHPPRVPPTRPGAVVAPADGEICVIDFATPPAELSMGDAALPRVSIFLSLLDAHVQRAPVSGEVIAVQHRPGRFGSADLAAASTENERTSLVIRTPGGADVVAVQVAGLLARRIICDAHVGDKLSIGDTYGLIRFGSRLDTYLPAGCEPLVKVGQRAIAGETVLAELP
>NC_016946.1|WP_008261338.1|4815693_4816554_+|CDP-diacylglycerol--serine-O-phosphatidyltransferase
MISKPRGRAVNLQILPSAMTVLSVCAGLTSIRFALEHQPKAAMALIAAAAILDGLDGRVARILDAQSRMGEEIDSLADAVNFGVTPAIVLYVTLLTNSPAGWVVILLYAVCVVLRLARFNALQDDGSQPAYTHEFFVGMPAPAGAISMIGLIGLKLQFGDGWWTSPLFLCIWITGTSILMVSKIPMRKMHAVAVPPSWAAPLLAILAICAAAAVLAPYVLIWVIIIAYLCHVPFAIRNQRWLAAHPEAWDDEPKQRRATRRAIRRAQPNRRSVARLGLRKPGRRVP

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Crispr_ID: NC_016946_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016946_7

4924802-4924929

Orphan

Consensus_repeat	Method
ATCGCCGGCGGCGCCAAGAAACCCGGGGCCAAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_016946_7

>merge|NC_016946|7|4924802-4924929|CRISPRCasFinder
ATCGCCGGCGGCGCCAAGAAACCCGGGGCCAAGAAAGCCGCGCCCGCCGCGGAAGGCAAGGCCGAAGCGGCCGCCCCGGTCAAGGGGCTGGGCATCGCCGGCGGCGCCAAGAAACCAGGGGCCAAGAA

>NC_016946|7|7|4924802-4924929|CRISPRCasFinder
ATCGCCGGCGGCGCCAAGAAACCCGGGGCCAAGAA	AGCCGCGCCCGCCGCGGAAGGCAAGGCCGAAGCGGCCGCCCCGGTCAAGGGGCTGGGC
ATCGCCGGCGGCGCCAAGAAACCAGGGGCCAAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_016946.1\|WP_014381307.1\|4914471_4915701_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377558
NC_016946.1\|WP_029384537.1\|4916273_4916999_+\|hypothetical-protein	unknown	unknown	unknown
NC_016946.1\|WP_179293540.1\|4917794_4919252_-\|sugar-porter-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340917
NC_016946.1\|WP_009954014.1\|4929317_4930073_-\|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	unknown	unknown	gnl\|CDD\|274422
NC_016946.1\|WP_179293542.1\|4934407_4935823_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237030
NC_016946.1\|WP_179293541.1\|4919809_4920394_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|252996
NC_016946.1\|WP_009954017.1\|4925415_4926720_+\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|181738
NC_016946.1\|WP_009954030.1\|4913766_4914360_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237874
NC_016946.1\|WP_009954024.1\|4917018_4917747_+\|hypothetical-protein	unknown	unknown	unknown
NC_016946.1\|WP_009954016.1\|4926752_4928018_+\|YibE/F-family-protein	unknown	unknown	gnl\|CDD\|377940
NC_016946.1\|WP_009954032.1\|4910950_4911592_-\|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl\|CDD\|237623
NC_016946.1\|WP_009954015.1\|4928913_4929288_-\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|378915
NC_016946.1\|WP_008261583.1\|4932986_4934312_-\|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|223936
NC_016946.1\|WP_009954012.1\|4931069_4932392_+\|MHS-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340927
NC_016946.1\|WP_009954013.1\|4930173_4930830_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225136
NC_016946.1\|WP_008261569.1\|4928014_4928890_-\|glucose-1-phosphate-thymidylyltransferase-RfbA	unknown	unknown	gnl\|CDD\|130274
NC_016946.1\|WP_080552513.1\|4932410_4932875_-\|TauD/TfdA-family-dioxygenase	unknown	unknown	gnl\|CDD\|181947
NC_016946.1\|WP_009954020.1\|4920490_4922167_+\|Hsp70-family-protein	unknown	unknown	gnl\|CDD\|223520
NC_016946.1\|WP_009954031.1\|4911588_4913448_-\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|234715
NC_016946.1\|WP_026071153.1\|4915711_4916284_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_016946.1\|WP_014381307.1\|4914471_4915701_+\|hypothetical-protein	gnl\|CDD\|377558	pfam05818, TraT, Enterobacterial TraT complement resistance protein. The traT gene is one of the F factor transfer genes and encodes an outer membrane protein which is involved in interactions between an Escherichia coli and its surroundings.	0.00637593
NC_016946.1\|WP_179293540.1\|4917794_4919252_-\|sugar-porter-family-MFS-transporter	gnl\|CDD\|340917	cd17359, MFS_XylE_like, D-xylose-proton symporter and similar transporters of the Major Facilitator Superfamily. This subfamily includes bacterial transporters such as D-xylose-proton symporter (XylE or XylT), arabinose-proton symporter (AraE), galactose-proton symporter (GalP), major myo-inositol transporter IolT, glucose transport protein, putative metabolite transport proteins YfiG, YncC, and YwtG, and similar proteins. The symporters XylE, AraE, and GalP facilitate the uptake of D-xylose, arabinose, and galactose, respectively, across the boundary membrane with the concomitant transport of protons into the cell. IolT is involved in polyol metabolism and myo-inositol degradation into acetyl-CoA. The XylE-like subfamily belongs to the Glucose transporter -like (GLUT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.64333e-98
NC_016946.1\|WP_009954014.1\|4929317_4930073_-\|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	gnl\|CDD\|274422	TIGR03083, TIGR03083, uncharacterized Actinobacterial protein TIGR03083. This protein family pulls together several groups of proteins, each very different from the others. They share in common three conserved regions. The first is a region of about 38 amino acids, nearly always at the N-terminus of a protein. This region has a bulky hydrophobic residue, usually Trp, at position 29, and a His residue at position 37 that is invariant, so far, in over 150 instances. The second conserved region has a motif [DE]xxxHxxD. The third conserved region contains a hydrophobic patch and a well-conserved Arg residue. Most examples are found in the Actinobacteria, including the genera Mycobacterium, Corynebacterium, Streptomyces, Nocardia, Frankia, etc. The pattern of near-invariant residues against a backdrop of extreme sequence divergence suggests enzymatic activity and conservation of active site residues.	4.08521e-17
NC_016946.1\|WP_179293542.1\|4934407_4935823_-\|hypothetical-protein	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	1.87892e-14
NC_016946.1\|WP_179293541.1\|4919809_4920394_+\|hypothetical-protein	gnl\|CDD\|252996	pfam05086, Dicty_REP, Dictyostelium (Slime Mold) REP protein. This family consists of REP proteins from Dictyostelium (Slime molds). REP protein is likely involved in transcription regulation and control of DNA replication, specifically amplification of plasmid at low copy numbers. The formation of homomultimers may be required for their regulatory activity.	7.66132e-05
NC_016946.1\|WP_009954017.1\|4925415_4926720_+\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|181738	PRK09265, PRK09265, aminotransferase AlaT; Validated.	0
NC_016946.1\|WP_009954030.1\|4913766_4914360_+\|hypothetical-protein	gnl\|CDD\|237874	PRK14971, PRK14971, DNA polymerase III subunit gamma/tau.	4.50153e-07
NC_016946.1\|WP_009954016.1\|4926752_4928018_+\|YibE/F-family-protein	gnl\|CDD\|377940	pfam07907, YibE_F, YibE/F-like protein. The sequences featured in this family are similar to two proteins expressed by Lactococcus lactis, YibE and YibF. Most of the members of this family are annotated as being putative membrane proteins, and in fact the sequences contain a high proportion of hydrophobic residues.	1.31151e-76
NC_016946.1\|WP_009954032.1\|4910950_4911592_-\|nucleotide-exchange-factor-GrpE	gnl\|CDD\|237623	PRK14142, PRK14142, heat shock protein GrpE; Provisional.	3.78199e-100
NC_016946.1\|WP_009954015.1\|4928913_4929288_-\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	0.000435505
NC_016946.1\|WP_008261583.1\|4932986_4934312_-\|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	gnl\|CDD\|223936	COG1004, Ugd, Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane].	0
NC_016946.1\|WP_009954012.1\|4931069_4932392_+\|MHS-family-MFS-transporter	gnl\|CDD\|340927	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.26975e-134
NC_016946.1\|WP_009954013.1\|4930173_4930830_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	1.29167e-26
NC_016946.1\|WP_080552513.1\|4932410_4932875_-\|TauD/TfdA-family-dioxygenase	gnl\|CDD\|181947	PRK09553, tauD, taurine dioxygenase; Reviewed.	1.369e-37
NC_016946.1\|WP_009954020.1\|4920490_4922167_+\|Hsp70-family-protein	gnl\|CDD\|223520	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones].	1.27594e-32
NC_016946.1\|WP_009954031.1\|4911588_4913448_-\|molecular-chaperone-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NC_016946.1\|WP_008261569.1\|4928014_4928890_-\|glucose-1-phosphate-thymidylyltransferase-RfbA	gnl\|CDD\|130274	TIGR01207, Glucose-1-phosphate_thymidylyltransferase_1, glucose-1-phosphate thymidylyltransferase, short form. Alternate name: dTDP-D-glucose synthase homotetramer This model describes a tightly conserved but broadly distributed subfamily (here designated as short form) of known and putative bacterial glucose-1-phosphate thymidylyltransferases. It is well characterized in several species as the first of four enzymes involved in the biosynthesis of dTDP-L-rhamnose, a cell wall constituent and a feedback inhibitor of the enzyme. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0

>NC_016946.1|WP_009954020.1|4920490_4922167_+|Hsp70-family-protein
MSQSLGLSIGVANLVAARAGTAPVTRSSVVTLFEHRPTEVGLPEENPNLTAPGLVLRGFVERVGDRAPLVAADGTKYLGAALTVEAIEAMARTVGYGTPISIAVPAYWSDEQFAALRDEFFAQSDLARGGVAPMLVSDATAAVAALRGTPGFPADGVVALCDFGAGGTTVTVLDANAGFAPVAPAVRHTDFSGDAIDQLIVDHLLASDVSTAVLGGGARMGSQTRLLAACRRAKEQLSTAAVSTVAGASGESTQLTRTEFEQLISPPLDRFVTSLQDTLRRNGIPNTNLRAVAIVGGGASIPLITARLSQRFGVPVRSAAQPASLAALGAAALGAQYAAGGAETTAAAAVETPTEMVGTAGIGATQAAWAAQATDVDDALAWSQDADSDEPVPYTGRDATGEYASEAREFEYPEQGGLPWYKRTALVLTVAGAGVAVLVAAALAIGLLMTKSTPAPPTSSPNPPPPPQTVTITGPNDSTTVTVVPAPPPPSSEAPATTTTTTPPPEPSTTTTTPPPSTTTTTTAPPTTTSQVTTTSAAPTTTTRVRPLPPIFQPPFGR
>NC_016946.1|WP_179293541.1|4919809_4920394_+|hypothetical-protein
MSRLAGAVSTIGAVASNGPRDDFHNRPTQHADFGMSEPPTGEVPPPNFPPQPPHGFEQPQGFDPFDQEPEPTPWYRRPAMLIAWLISVVILIGLIVFGIIELIHDDQSVNHVPKSTTSTTTTTTTTTPSTTTTTTTTESSSSAEEQPPAQQPTQQQPTGQQTQQPTHRHHLPQLPPVITIPQVPTVITVPPGLR
>NC_016946.1|WP_179293540.1|4917794_4919252_-|sugar-porter-family-MFS-transporter
MPNGTDPAKCADAAHEGASQRAVGAVAEAGSQLTSAVVVIALVSAISGLLYGYNTGVISWALLQLTEEFNLTAAWKQVVAASILLGAIVGALACSWLSDRFGRRGTLLMLAVLFIVGALWCADAPDVVVLSLGRLVLGFAVGGATQTAPMYVAELSPSAYRGRLVLCFQIAIGVGILAANLIGVFDSVSWRGPTGIACVPAAIMLWLLLRLPESPRWLVKQGDRNAARAVLERVRPDGYDVGAELDEATELARMERKASTRGWSGLRDAWVRPALVLGCGIAVFTQLSGIEMIIYYAPTILTDDGVYRSVALLVSVMLGATYVIAQLVGLAIIDRVGRRRLTLIMVPGAAISLFALGLIFVTADSGRDVIAYIMISLIAFMVFNAGGLQLMGWLTGSETYPLAVRPEGTAVHSATLWGTNLLITLTLLSLINAIGVGPSMWLYALFNVAAWIFVFFRMPDLTGKSLEEIEKNLAEGKFRPSDFAR
>NC_016946.1|WP_009954024.1|4917018_4917747_+|hypothetical-protein
MINGETSGQWRRGLRYTFGAALLLLAAVAASVGVRWYLSLIAFCAALMFILGRRRIFRPGVTRAGDEIICRYIPWYEGNVYVLNVLFPLLAVAGIGAGSAPGNPAWLRFIGILLLVLTPIFVSSAVRMWRRCLLCISPSVLTVRLTAPKEELTEISRECVVSIEPKIVPNGVSGQSLQVAISYRATGLSSESKTVLLGLQLTIQPINLLNALIAWKDGAHENPCELLDRIERILRGQSMAGV
>NC_016946.1|WP_029384537.1|4916273_4916999_+|hypothetical-protein
MASNTAKRRVPKLRYAVGGALCLLAGINVLVGSAWYLPVGAAAVGVGIIYGSGRRIFGAGVRRTGQEIVCRYLPWYESNPYMATLLFPLIAIAMIGAGCAPGNPAWLWYGGAILLAISALLVGVSLWIWRRSLLRITPAALTVRIAERGSELTDIRREHVRSIEPKLVPSVAAGTERLQVEVAYQPADVSSEATATVMLGMYLSVQPINLLNALVAWKDGGHENPCELLDQVEGILRGNSQ
>NC_016946.1|WP_026071153.1|4915711_4916284_+|hypothetical-protein
MRFDEFTEEHGLAVSPVDRFVGFVVEVGVPPGWEPFESAEGVRVWVCRADPCIDVFCANAVLTMHRVEASLDPPEVFAMLSDQQLQSAPKCRELHREFTAAREGPGSAGTLAIQIAHELGTIDSTSQSRIITAERETLIAQLTVTALHDSPMDGSGVWLTTRSGPVTNPTSAGYHGAIPRTEHGTVADGK
>NC_016946.1|WP_014381307.1|4914471_4915701_+|hypothetical-protein
MQLRYISVAALIAEAGGDPWAVNQSLQAGSPFQIAQLAEAFLKAGRCTAEATNAFDQARSRFDAAWNHQNGDHPINGSAEVQRVTKSLGAQSLQLPKIGADLENIAANLAEAQKSAAGQIAALESQLQQLDGFIGQAVELEKDPTLTAEDRHALDAFISGREDDAIRDTKAALGQLQSTRDGYANSFQNAMGTLHADGYDLTAPQTGPAQGAAEQPGGGAAEQPGGGPALAPTKGEVLTGAAGAIAGGTADGVRGATTRLIAESPGTGPGKADPGLLRWFEDPKIGGIELKGFSRVGGVVAAASAVPAVMSDIHDGNSVPEAVTRESAGVAAGLAAGGWVGGAVAGSELGAALGSVVPGAGTAVGLVAGAVVGAGAAFVASKTVEVAWQPAADAIGSVVHGVESVFGFG
>NC_016946.1|WP_009954030.1|4913766_4914360_+|hypothetical-protein
MRFSDNVRRSLAGGSLLLVALFAGSGLVSGCSSVIGGRPVASPGAGAGEPSFPTPRSTPSPPSATAAPAPTAPAAPTGPTNPAGAIPLPPDQNGYVFIETKSGVTRCQINKDTVGCEAPFTNSPLQDGEHANGVSVTTGGKVQWVLGNLGAIPTVKIDYQTYAAQGWTIIANVDGTRFTNDQTKHGMFVSIDKVNTF
>NC_016946.1|WP_009954031.1|4911588_4913448_-|molecular-chaperone-DnaK
MARAVGIDLGTTNSVVAVLEGGDPVVVANSEGSRTTPSIVAFARNGEVLVGQPAKNQAVTNVDRTIRSVKRHMGTDWSIEIDDKKYTAQEISARVLMKLKRDAEAYLGEDVTDAVVTVPAYFNDAQRQATKEAGQIAGLNVLRIVNEPTAAALAYGLDKGEKEQTILVFDLGGGTFDVSLLEIGEGVVEVRATSGDNHLGGDDWDDRVVDWLVDKFKGTSGIDLTKDKMAMQRLREAAEKAKIELSSSQSTSINLPYITVDADKNPLFLDEQLTRAEFQRITQDLLDRTRQPFQSVIKDAGISVSEIDHVVLVGGSTRMPAVTELVKELTGGKEPNKGVNPDEVVAVGAALQAGVLKGEVKDVLLLDVTPLSLGIETKGGVMTKLIERNTTIPTKRSETFTTADDNQPSVQIQVYQGEREIASHNKLLGSFELTGIPPAPRGVPQIEVTFDIDANGIVHVTAKDKGTGKENTIKIQEGSGLSKEEIDRMIKDAEAHAEEDRQRREEADVRNQAESLVYQTEKFVKDQREAEGGSKVPEDTLSKVDAAIAEAKTALGGTDITAIKSAMEKLGQESQALGQAIYEATQAAGEQTDATGGGQAGSADDVVDAEVVDDDRESK
>NC_016946.1|WP_009954032.1|4910950_4911592_-|nucleotide-exchange-factor-GrpE
MTEGNPQEQVTVTDKRRIDPETGEVRQVPPGDTPGGPAPADEPAVQGEGKLAELTADLQRVQADFANYRKRALRDQQAAADRAKAAVVNQLLGVLDDLDRARKHGDLESGPLKAVADKLEGALTGLGLTAFGEEGEDFDPVLHEAVQHEGDGSRPVIGTVMRQGYKLGDQILRHAMVGVVDTVDDEGDESASAGEAEETAPVESDDNAGTSGD
>NC_016946.1|WP_009954017.1|4925415_4926720_+|pyridoxal-phosphate-dependent-aminotransferase
MDSDGTIGDVTTHQLPHQLPPHPSAHHRQQRTFVQSSKLQDVLYEIRGPVHQQAARLEAEGHRILKLNIGNPAPFGFEAPDVIMRDMIQALPYAQGYSDSQGILPARRAVVTRYELVDGFPRFDVDDVYLGNGVSELITMTLQALLDNGDEVLIPSPDYPLWTASTSLAGGTPVHYLCDETQGWQPDIADMESKITDRTKALVVINPNNPTGAVYTSEVLTQIVELARKHELLLLADEIYDKILYGDAKHINLASLAPDMLCLTFNGLSKAYRVAGYRAGWLAITGPKDHAGSFIEGINLLANMRLCPNVPAQHAIQVALGGYQSIDDLVLPGGRLLEQRDVAWTKLNEIPGVSCVKPDGALYAFPRLDPEVYDIDDDEQLVLDLLLQEKILVTQGTGFNWPAPDHLRIVTLPWARDLAAAIERLGNFLVAYRQ
>NC_016946.1|WP_009954016.1|4926752_4928018_+|YibE/F-family-protein
MTHSHSHSLPPGPSGIDPLPARIVVGLLVAIGVAVAVGAILLWPSRQRVDIPMPLQNASGGAVSTQAGHVLSSGLGDCGSPSVSQVLTGPPKPAAPGAGRCVLTQVAVDSGPNAGATTLLESSPGPGQPKFAVGDRIRVVRQVDDQGATSYAFYDFERGWALVGLAIAFAVVIVAVARWRGLLALVGILVAFVVLVMFLLPALRDGAPAVPVALVASAAILYAVIYLAHGVSLRTSAALLGTLSALLLAAGLSWAAIQLAHLTGLSDEQNTTVSAYLGNVSIGGLLLAGFIIGSLGVLNDVTVTQSSTVFELARLGGSRRAIFVGAIRVGRDHIASTVYTLVLAYAGSSLPLLLLFSVANRSLTDVLTGESVAIEIARSAVGGMALALSVPLTTGIAAVLAKPSGGRKRGEAARSGPPPPA
>NC_016946.1|WP_008261569.1|4928014_4928890_-|glucose-1-phosphate-thymidylyltransferase-RfbA
MRGIILAGGSGTRLHPITTGISKQLLPVYDKPMVYYPLSTLMMAGIRDILVITTPHDAPGFQRLLGDGSQFGVNITYVTQDRPDGLAQAFVLGADHIGNESVALVLGDNIFYGPGLGTSLRRFQTISGGAVFAYWVANPSAYGVVEFSDDGLALSLEEKPKTPKSNYAVPGLYFYDNDVIEIAKGLKKSARGEYEITEVNQIYLNRGRLSVEVMARGTAWLDTGTFDSLLDASDFVRTLERRQGLKVSVPEEVAWQQGWITDEQLAQRAHSLLKSGYGSYLLNLLERSRFH
>NC_016946.1|WP_009954015.1|4928913_4929288_-|nuclear-transport-factor-2-family-protein
MTTSEIATVLAWHDALNAADIETLASLSSDDIEMGDAHGAAQGHEALRSWAASHRPATELGRMYVHDGVVAVELKPGSTGDPGAATDAALTFRVVRDHVTSVFRHDSLASALAATELTESDAVD
>NC_016946.1|WP_009954014.1|4929317_4930073_-|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme
MDYAGAFLDQNRAFAELFDGADESTPVPTCPEWTLRQLFRHVGRGDRWAAQIVRDRLESYLDPRTVEGGKPPPDPADAISWLHGGAQRLVDAVELTGVETPVWTFLGPRPANWWIRRRLHEVAVHRADAAIALGTDFALEPDIAADGITEWLERVAIQAGGQGAPLPLEDGTTLHLHATDPGLGEAGEWTAAVDQGRVTWSHEHGKGSVALRGGATELLLAILRRRPLADTGVQLFGDEAVWERWLDRTPL
>NC_016946.1|WP_009954013.1|4930173_4930830_+|class-I-SAM-dependent-methyltransferase
MLADSAGLPDAHAAIRAFWEREGSEYDQRAAHGISSEPERRLWTAALSAIPERSRVLDIATGTGFVALLLSELGHRVTGVDASEAMLARARAKAAATAATVEFVEGVTEELPFPDASFDALTARHFIWTLLEPEKAFAEWRRVLAPDATLIADVSLNPHVAGHHYADDVAAALPFRALSDAAPVADALRSAGFEHVRIDLSRDGGEYPRAMLHARAGQ
>NC_016946.1|WP_009954012.1|4931069_4932392_+|MHS-family-MFS-transporter
MTIAEQESSRAATPPEEAAPVPDMRRVALASLAGSVLEWYDFFLYGFAATLVFGPLFFPRASATAGVLAALGTFAVGFVARPLGGVVFGHLGDRLGRKKMLVATLLIMGIPSFLIGLLPSYSAIGWSAPALLVLLRFLQGVGLGGEWAGAVLVVTETSPPHRSGFWGSLVQTGATLGQGLATGSLFILASLLSEHSFVTWGWRVPFLFGIALSVVGLFIRLRVMESPEFTALHRSGELSRFPLREAVRQHGRTMLVCFGVYLGGVTVPFFVETVFLTGYGTKSLALPASSVLLGISAVHVTVFWVLTLLGGWLADRVGAPRVVRAGLLGLLVLPTAGLLAVLSASSTVAALLITETLIGAPMWVVWGALPKYLAESFPARVRYTGMSLSGQSSTIIGGLIPLLLTSVIAHVGGALWPVALTTTAVAAFGVLGLLWSHRSR
>NC_016946.1|WP_080552513.1|4932410_4932875_-|TauD/TfdA-family-dioxygenase
MVRGFIDGLRAEHRFGATLAFERSAEKIGELVRGKPLAAIHPVVRVHPETNERVVYVNQFFTKEIVDLSPRESRHVLGLLFEQISRPEYSVRFKWEPGSVAFWDNRATLHLAPRDFEHLDHERVLHRTTLVGDIPVGPDGRPSEPLEGQFFGAA
>NC_016946.1|WP_008261583.1|4932986_4934312_-|UDP-glucose/GDP-mannose-dehydrogenase-family-protein
MRCTVFGTGYLGATHAVGMAALGHDVLGIDIDPGKVAKLAGGDIPFYEPGLRKLLNENLAAGRLRFTTDYDAAADFADLHFLGVGTPQKKGEYGADLRHVYAVIDELVPRLTSSAVLVGKSTVPVGTAAELNQRAAALAPRGVDVEIAWNPEFLREGYAVQDTLRPDRIVLGVHQDSVRAEAAVRELYGPLLDAGVPFLVTDLQTAELVKVSANAFLATKISFINAISEVCEAAGADVSLLADALGYDPRIGRQFLNAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSINMRRRTRMVELASAACGGSLLGANVAVLGAAFKPESDDVRDSPALNVAGQLQLNGAAVNVYDPKALDNAQRLFPTLNYAVSVEEACERADAVLVLTEWRQFVELDPDDLADGVRARVIVDGRNCLDTARWQRAGWRVYRLGAPRP
>NC_016946.1|WP_179293542.1|4934407_4935823_-|hypothetical-protein
MVLVEGENGDGATVDEDNFDVTTSTDAATVTASDQVVSAILGTRQGAAEGGYQLASTGVTFTDPVEAAALRDKLAAHKVENVMLVSAFLAAAALAQAVGHRTNYAQTALLYIEPETATLAIVDSADGSIADVRRQVLPEDDEAAVAELTRLVSGAENMESRPDAVFVVGSGIDIPLIKPALEAATTLPLTAAEEPETALARGAALASAHAPLFASSTAALAYAQDPGTGAINPLAVAPGYFDAPGDAGVDALAYSAVPDDPDDFFTGSQTAATELVGAEYRGRNFKLVGSAVAAVFVIGVVALVVSLAIAIRPTANVRPSPNENVVVAPTRPAPAPAAPAPAQAPAAPAPAPEAPAPVPEAPAPAPAAPAPAPVAPAPIPVPAAPPPAPAPPPVAPVPVPIPLPIPGIGGPPGGGWGPGHGGGHGDHDDGFPGGPRGGFGGGPRGGFGGGHGHGGFGGGGPRINIPGIPGI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NC_016946.1	1110669-1110693	2	0.92
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NC_016946.1	1110724-1110748	2	0.92
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NC_016946.1	1261139-1261163	2	0.92
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NC_016946.1	1261196-1261220	2	0.92
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NC_016946.1	3975523-3975547	2	0.92
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NC_016946.1	3975577-3975601	2	0.92

1. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to position: 1110669-1110693, mismatch: 2, identity: 0.92

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ggcgcagcgggtcaccaccatcgac	Protospacer
*************.*****.*****

2. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to position: 1110724-1110748, mismatch: 2, identity: 0.92

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ggcgcagcgggtcaccaccatcgac	Protospacer
*************.*****.*****

3. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to position: 1261139-1261163, mismatch: 2, identity: 0.92

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ggcgcagcgggtcgccaccatcaac	Protospacer
*******************.**.**

4. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to position: 1261196-1261220, mismatch: 2, identity: 0.92

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ggcgcagcgggtcgccaccatcaac	Protospacer
*******************.**.**

5. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to position: 3975523-3975547, mismatch: 2, identity: 0.92

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ggcgaagcgggtcgccaccatcgac	Protospacer
**** **************.*****

6. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to position: 3975577-3975601, mismatch: 2, identity: 0.92

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ggcgaagcgggtcgccaccatcgac	Protospacer
**** **************.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1297992-1298016	3	0.88
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	MN234183	Mycobacterium phage Antsirabe, complete genome	13503-13527	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1905470-1905494	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1412934-1412958	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	780363-780387	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1114079-1114103	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1283751-1283775	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1283695-1283719	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NZ_CP023455	Rhodobacteraceae bacterium QY30 plasmid unnamed, complete sequence	23419-23443	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	772105-772129	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	375411-375435	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	MH727544	Mycobacterium phage Dalmuri, complete genome	23817-23841	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	MN234198	Mycobacterium phage Zavala, complete genome	23759-23783	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	MF140412	Mycobacterium phage Jeckyll, complete genome	23817-23841	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	KY380102	Mycobacterium phage CREW, complete genome	23817-23841	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	MH536822	Mycobacterium phage Joy99, complete genome	23746-23770	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	KJ567045	Mycobacterium phage Emerson, complete genome	23777-23801	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	JN185608	Mycobacterium virus JAWS, complete genome	23771-23795	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	MN908692	Mycobacterium Phage BGlluviae, complete genome	23817-23841	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NC_023747	Mycobacterium phage BarrelRoll, complete genome	23769-23793	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	MH536821	Mycobacterium phage Homura, complete genome	23817-23841	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	MH697578	Mycobacterium phage Belladonna, complete genome	23817-23841	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	MH077577	Mycobacterium phage AlishaPH, complete genome	23776-23800	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	MH509444	Mycobacterium phage BEEST, complete genome	23817-23841	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	MN369742	Mycobacterium phage Spock, complete genome	23817-23841	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	MK112537	Mycobacterium Phage Capricorn, complete genome	23817-23841	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	MN369746	Mycobacterium phage Inky, complete genome	23817-23841	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	MH513977	Mycobacterium phage Mynx, complete genome	23800-23824	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	MN234197	Mycobacterium phage Ramen, complete genome	23783-23807	4	0.84
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1575877-1575901	5	0.8
NC_016946_3	3.1\|2513056\|25\|NC_016946\|CRISPRCasFinder	2513056-2513080	25	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	237391-237415	5	0.8
NC_016946_1	1.1\|27150\|34\|NC_016946\|CRISPRCasFinder	27150-27183	34	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	555402-555435	8	0.765
NC_016946_1	1.1\|27150\|34\|NC_016946\|CRISPRCasFinder	27150-27183	34	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	549521-549554	8	0.765
NC_016946_1	1.1\|27150\|34\|NC_016946\|CRISPRCasFinder	27150-27183	34	NZ_CP012916	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence	187854-187887	9	0.735
NC_016946_1	1.1\|27150\|34\|NC_016946\|CRISPRCasFinder	27150-27183	34	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	283810-283843	9	0.735
NC_016946_1	1.1\|27150\|34\|NC_016946\|CRISPRCasFinder	27150-27183	34	NZ_CP032341	Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence	52186-52219	9	0.735
NC_016946_1	1.1\|27150\|34\|NC_016946\|CRISPRCasFinder	27150-27183	34	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	570738-570771	9	0.735
NC_016946_1	1.1\|27150\|34\|NC_016946\|CRISPRCasFinder	27150-27183	34	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1389609-1389642	9	0.735
NC_016946_1	1.1\|27150\|34\|NC_016946\|CRISPRCasFinder	27150-27183	34	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	143016-143049	9	0.735
NC_016946_1	1.1\|27150\|34\|NC_016946\|CRISPRCasFinder	27150-27183	34	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	279122-279155	9	0.735
NC_016946_1	1.1\|27150\|34\|NC_016946\|CRISPRCasFinder	27150-27183	34	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	1561646-1561679	9	0.735

1. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 3, identity: 0.88

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
cgcgcagcgggtcgctgccgtcgac	Protospacer
 **************..********

2. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to MN234183 (Mycobacterium phage Antsirabe, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
cgcgcaccgggtcgccaccgtcgcg	Protospacer
 ***** ****************

3. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
agcgcagcggggcgccaccgtccag	Protospacer
.********** ********** *

4. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
cccgccgccggtcgccaccgtcgac	Protospacer
  *** ** ****************

5. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ggcgcggcgggtcgccaccggcgcg	Protospacer
*****.************** **

6. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ggcgcggcgggtcgccaccggcgcg	Protospacer
*****.************** **

7. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ggcgcggcgggtcgccaccggcgcg	Protospacer
*****.************** **

8. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ggcgcggcgggtcgccaccggcgcg	Protospacer
*****.************** **

9. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to NZ_CP023455 (Rhodobacteraceae bacterium QY30 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ggcgcagcgggtggccagcgtcgcg	Protospacer
************ **** *****

10. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ggcgcggcgggtcgccaccggcgcg	Protospacer
*****.************** **

11. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
atcgcagcgcgtcgccaccgccgac	Protospacer
. ******* **********.****

12. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to MH727544 (Mycobacterium phage Dalmuri, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

13. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to MN234198 (Mycobacterium phage Zavala, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

14. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to MF140412 (Mycobacterium phage Jeckyll, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

15. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to KY380102 (Mycobacterium phage CREW, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

16. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to MH536822 (Mycobacterium phage Joy99, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

17. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to KJ567045 (Mycobacterium phage Emerson, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

18. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to JN185608 (Mycobacterium virus JAWS, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

19. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to MN908692 (Mycobacterium Phage BGlluviae, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

20. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to NC_023747 (Mycobacterium phage BarrelRoll, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

21. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to MH536821 (Mycobacterium phage Homura, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

22. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to MH697578 (Mycobacterium phage Belladonna, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

23. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to MH077577 (Mycobacterium phage AlishaPH, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

24. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to MH509444 (Mycobacterium phage BEEST, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

25. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to MN369742 (Mycobacterium phage Spock, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

26. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to MK112537 (Mycobacterium Phage Capricorn, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

27. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to MN369746 (Mycobacterium phage Inky, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

28. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to MH513977 (Mycobacterium phage Mynx, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

29. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to MN234197 (Mycobacterium phage Ramen, complete genome) position: , mismatch: 4, identity: 0.84

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ttcgcagcggttcgccaccgtcggc	Protospacer
  ******** ************.*

30. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 5, identity: 0.8

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ccaccagcgggtcgacaccgtcgac	Protospacer
    ********** **********

31. spacer 3.1|2513056|25|NC_016946|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 5, identity: 0.8

ggcgcagcgggtcgccaccgtcgac	CRISPR spacer
ccaccagcgggtcgacaccgtcgac	Protospacer
    ********** **********

32. spacer 1.1|27150|34|NC_016946|CRISPRCasFinder matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 8, identity: 0.765

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
gaactggtgcaggtagcccggctgcggcgacaca	Protospacer
* .***** * ******************.   *

33. spacer 1.1|27150|34|NC_016946|CRISPRCasFinder matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.765

gcgctggtcctggtagcccggctgcggcgggtaa-	CRISPR spacer
gaactggtgcaggtagcccggctgcgg-ggacacc	Protospacer
* .***** * **************** **..*

34. spacer 1.1|27150|34|NC_016946|CRISPRCasFinder matches to NZ_CP012916 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence) position: , mismatch: 9, identity: 0.735

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
gaactggtgcaggtagcccggctgcggcgacacc	Protospacer
* .***** * ******************.

35. spacer 1.1|27150|34|NC_016946|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 9, identity: 0.735

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
gaactggtgcaggtagcccggctgcggcgacacc	Protospacer
* .***** * ******************.

36. spacer 1.1|27150|34|NC_016946|CRISPRCasFinder matches to NZ_CP032341 (Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.735

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
gaactggtgcaggtagcccggctgcggcgacacc	Protospacer
* .***** * ******************.

37. spacer 1.1|27150|34|NC_016946|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.735

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
ctgatcgtcctgatcgcccggctgcggcgggagg	Protospacer
 .* * ******.* **************** ..

38. spacer 1.1|27150|34|NC_016946|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.735

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
ctgatcgtcctgatcgcccggctgcggcgggagg	Protospacer
 .* * ******.* **************** ..

39. spacer 1.1|27150|34|NC_016946|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 9, identity: 0.735

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
ctgatcgtcctgatcgcccggctgcggcgggagg	Protospacer
 .* * ******.* **************** ..

40. spacer 1.1|27150|34|NC_016946|CRISPRCasFinder matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 9, identity: 0.735

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
ctgatcgtcctgatcgcccggctgcggcgggagg	Protospacer
 .* * ******.* **************** ..

41. spacer 1.1|27150|34|NC_016946|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 9, identity: 0.735

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
ctgatcgtcctgatcgcccggctgcggcgggagg	Protospacer
 .* * ******.* **************** ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 11107

Mycobacterium_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014378740.1\|2070_3270_+	DNA polymerase III subunit beta	G8I4E4	Mycobacterium_phage	8.3e-68	41.5
WP_014378741.1\|3270_4428_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_014378742.1\|4424_4988_+	DUF721 family protein	NA	NA	NA	NA
WP_009954877.1\|5245_7279_+	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	2.7e-135	43.1
WP_014378743.1\|7330_11107_+	intein-containing DNA gyrase subunit A	U5J9D0	Bacillus_phage	1.0e-50	27.2

DBSCAN-SWA_2

15121 : 21285

Bodo_saltans_virus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008262529.1\|15121_15670_+	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	7.5e-24	44.6
WP_080587904.1\|15692_16118_-	PH domain-containing protein	NA	NA	NA	NA
WP_003872098.1\|16273_16555_-	cell division protein CrgA	NA	NA	NA	NA
WP_014378748.1\|16684_17428_+	DUF881 domain-containing protein	NA	NA	NA	NA
WP_008262550.1\|17472_18159_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	3.7e-44	47.4
WP_014378749.1\|18136_20017_-	Stk1 family PASTA domain-containing Ser/Thr kinase	L7RGQ5	Acanthamoeba_polyphaga_moumouvirus	6.1e-17	35.1
WP_041297605.1\|20013_21285_-	serine/threonine protein kinase	A0A2R8FF19	Brazilian_cedratvirus	3.2e-17	28.9

DBSCAN-SWA_3

39344 : 40163

Rhodococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952741.1\|39344_40163_+	C40 family peptidase	A0A1W6DXV0	Rhodococcus_phage	5.2e-21	55.4

DBSCAN-SWA_4

50084 : 55048

Staphylococcus_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954165.1\|50084_52994_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	7.9e-213	45.1
WP_009954166.1\|52999_53671_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_009954167.1\|53728_54232_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_014381572.1\|54298_55048_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.6e-22	34.2

DBSCAN-SWA_5

66821 : 67916

Stenotrophomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008262662.1\|66821_67916_-	inositol-3-phosphate synthase	A0A0H4IPK5	Stenotrophomonas_phage	4.6e-73	42.2

DBSCAN-SWA_6

75523 : 78728

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008262692.1\|75523_76042_+	single-stranded DNA-binding protein	A0A2H4JEL4	uncultured_Caudovirales_phage	3.3e-53	86.1
WP_003874730.1\|76078_76333_+	30S ribosomal protein S18	NA	NA	NA	NA
WP_008262694.1\|76363_76822_+	50S ribosomal protein L9	NA	NA	NA	NA
WP_009952120.1\|77351_78728_+	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	1.6e-86	40.5

DBSCAN-SWA_7

88555 : 93338

Trichoplusia_ni_ascovirus(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952110.1\|88555_88759_+	cold-shock protein	Q9AZD3	Lactococcus_phage	1.7e-13	52.3
WP_008262709.1\|89113_89743_-	hypothetical protein	NA	NA	NA	NA
WP_009952109.1\|89827_90742_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_009952107.1\|91034_91592_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_009952106.1\|91674_92445_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	2.9e-13	29.0
WP_009952105.1\|92594_93338_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	5.4e-09	26.2

DBSCAN-SWA_8

98981 : 100415

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952095.1\|98981_100415_+	FAD-binding oxidoreductase	S4VRT3	Pandoravirus	1.5e-23	35.3

DBSCAN-SWA_9

104609 : 105194

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014378790.1\|104609_105194_+	N-acetyltransferase	A0A2H4J136	uncultured_Caudovirales_phage	1.5e-38	50.0

DBSCAN-SWA_10

129549 : 130521

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014378808.1\|129549_130521_+	2-hydroxyacid dehydrogenase	A0A1B1IVB5	uncultured_Mediterranean_phage	6.0e-16	29.6

DBSCAN-SWA_11

134068 : 134887

Lake_Baikal_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014378812.1\|134068_134887_-	CbbQ/NirQ/NorQ/GpvN family protein	A0A2H4N7N3	Lake_Baikal_phage	5.0e-16	28.2

DBSCAN-SWA_12

138273 : 144707

Burkholderia_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956874.1\|138273_139602_-	MFS transporter	Q6JIH2	Burkholderia_virus	7.6e-46	28.9
WP_014378815.1\|139891_140464_-	hemerythrin domain-containing protein	NA	NA	NA	NA
WP_009956872.1\|140805_141690_+	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	1.1e-27	30.5
WP_009956871.1\|141774_142329_+	hypothetical protein	NA	NA	NA	NA
WP_014378816.1\|142399_142753_+	VOC family protein	NA	NA	NA	NA
WP_041786997.1\|142749_143025_-	YdeI/OmpD-associated family protein	NA	NA	NA	NA
WP_009956865.1\|143021_143915_-	hypothetical protein	NA	NA	NA	NA
WP_014378818.1\|143987_144707_+	CoA pyrophosphatase	E5DQL1	Aeromonas_phage	9.2e-06	37.1

DBSCAN-SWA_13

154716 : 156045

Feldmannia_species_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956853.1\|154716_156045_+	HAMP domain-containing histidine kinase	B5LWN0	Feldmannia_species_virus	3.9e-10	26.1

DBSCAN-SWA_14

162320 : 167561

Mycobacterium_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014378831.1\|162320_163979_+\|protease	type VII secretion system ESX-2 serine protease mycosin MycP2	A0A0A7HDD8	Mycobacterium_phage	5.5e-70	36.2
WP_014378832.1\|163975_165598_+	type VII secretion protein EccE	NA	NA	NA	NA
WP_170320649.1\|165710_167561_+	type VII secretion system ESX-2 AAA family ATPase EccA2	V5UQM2	Mycobacterium_phage	2.3e-48	30.1

DBSCAN-SWA_15

182051 : 183266

uncultured_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014378838.1\|182051_183266_-	DNA polymerase IV	A0A218MNF2	uncultured_virus	2.1e-18	32.9

DBSCAN-SWA_16

190202 : 190826

Bacillus_thuringiensis_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007771867.1\|190202_190826_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	2.7e-38	44.1

DBSCAN-SWA_17

199300 : 200560

Orpheovirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008262975.1\|199300_200560_+\|tRNA	serine--tRNA ligase	A0A2I2L4X3	Orpheovirus	1.8e-52	33.3

DBSCAN-SWA_18

213152 : 214343

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263005.1\|213152_214343_+	UDP-galactopyranose mutase	E4ZFQ1	Streptococcus_phage	2.0e-85	43.4

DBSCAN-SWA_19

220182 : 222291

Macacine_betaherpesvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020188359.1\|220182_221226_+	esterase family protein	A0A2I6B0H1	Macacine_betaherpesvirus	8.1e-152	80.4
WP_008263024.1\|221388_222291_+	esterase family protein	A0A2I6B2Q9	Macacine_betaherpesvirus	4.1e-43	39.1

DBSCAN-SWA_20

257836 : 258634

Anomala_cuprea_entomopoxvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263074.1\|257836_258634_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	5.8e-09	23.3

DBSCAN-SWA_21

268261 : 269329

Pacmanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014378874.1\|268261_269329_-	pyridoxal phosphate-dependent aminotransferase	A0A1X6WGT4	Pacmanvirus	2.8e-14	25.1

DBSCAN-SWA_22

273418 : 282159

Mycobacterium_phage(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263106.1\|273418_273574_+	hypothetical protein	A0A1C9EH86	Mycobacterium_phage	7.5e-06	52.9
WP_008263107.1\|273727_274432_+	two-component system response regulator TcrX	W8CYM9	Bacillus_phage	1.3e-36	36.9
WP_170320650.1\|274493_275924_+	HAMP domain-containing protein	Q8QKV7	Ectocarpus_siliculosus_virus	7.2e-10	28.1
WP_008263112.1\|275924_276416_-	lipoprotein LpqH	NA	NA	NA	NA
WP_009956742.1\|276585_278460_+	MBL fold metallo-hydrolase	A0A2P0VMX1	Tetraselmis_virus	3.7e-139	46.4
WP_014378878.1\|278467_279436_-	NADPH:quinone oxidoreductase family protein	NA	NA	NA	NA
WP_009956740.1\|279435_280059_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_009956739.1\|280039_281323_-	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_009956738.1\|281394_282159_-	glucose 1-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	2.0e-19	31.6

DBSCAN-SWA_23

287170 : 288265

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014378880.1\|287170_288265_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.7e-22	35.9

DBSCAN-SWA_24

291910 : 292369

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263147.1\|291910_292369_+	nucleoside deaminase	S4VYT2	Pandoravirus	4.5e-06	37.1

DBSCAN-SWA_25

298539 : 302165

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263155.1\|298539_299025_-	NINE protein	A0A0A7RVM3	Mycobacterium_phage	1.0e-08	43.4
WP_008263157.1\|299153_299540_+	DUF2237 domain-containing protein	NA	NA	NA	NA
WP_009956720.1\|299640_300912_+	sulfotransferase	NA	NA	NA	NA
WP_008263162.1\|300926_302165_+	MBL fold metallo-hydrolase	A0A1V0SGC6	Hokovirus	2.4e-25	28.6

DBSCAN-SWA_26

316850 : 317840

Cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956710.1\|316850_317840_+	D-2-hydroxyacid dehydrogenase family protein	A0A1M7XU89	Cedratvirus	2.2e-26	32.6

DBSCAN-SWA_27

325976 : 326342

Streptomyces_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014378893.1\|325976_326342_-	hypothetical protein	A0A0U4K3G9	Streptomyces_phage	4.7e-14	44.9

DBSCAN-SWA_28

338309 : 339296

Cowpox_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263218.1\|338309_339296_-	SDR family NAD(P)-dependent oxidoreductase	G0XSR1	Cowpox_virus	5.7e-06	30.3

DBSCAN-SWA_29

345503 : 348673

Bacteriophage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014378911.1\|345503_347351_+	DNA polymerase III subunits gamma/tau	A0A1L2BWV7	Bacteriophage	2.3e-40	31.6
WP_009952023.1\|347362_348673_-	class I SAM-dependent methyltransferase	A0A2I2L5L3	Orpheovirus	2.8e-32	31.8

DBSCAN-SWA_30

354905 : 355898

Croceibacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263256.1\|354905_355898_+	DEDDh family exonuclease	I6R9X8	Croceibacter_phage	2.2e-10	29.5

DBSCAN-SWA_31

381889 : 382354

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263292.1\|381889_382354_+	GatB/YqeY domain-containing protein	A0A218KC79	Bacillus_phage	2.6e-09	35.6

DBSCAN-SWA_32

400070 : 403275

Tsukamurella_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263340.1\|400070_400421_+	WhiB family transcriptional regulator	A0A159B6S6	Tsukamurella_phage	1.3e-10	50.0
WP_008263342.1\|400433_401564_-	ArsA family ATPase	NA	NA	NA	NA
WP_008263344.1\|401560_402580_-	ArsA family ATPase	NA	NA	NA	NA
WP_008263345.1\|402643_402805_+	DUF4177 domain-containing protein	NA	NA	NA	NA
WP_008263347.1\|402807_403275_+	RidA family protein	M1I5B0	Acanthocystis_turfacea_Chlorella_virus	1.4e-15	33.6

DBSCAN-SWA_33

407794 : 413373

uncultured_Mediterranean_phage(50.0%)

holin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263368.1\|407794_408988_+\|protease	acid resistance serine protease MarP	A0A1B1IRH0	uncultured_Mediterranean_phage	9.9e-05	25.0
WP_014378947.1\|408980_409952_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_014378948.1\|409952_410471_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_020188338.1\|410708_411407_+	peptidase	NA	NA	NA	NA
WP_009954803.1\|411417_413373_-	acetate--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	2.4e-88	39.6

DBSCAN-SWA_34

418561 : 420181

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038538388.1\|418561_420181_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.1e-13	31.4

DBSCAN-SWA_35

428363 : 436586

uncultured_Mediterranean_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014378959.1\|428363_430697_-	DEAD/DEAH box helicase	A0A1B1IUF6	uncultured_Mediterranean_phage	4.6e-06	26.9
WP_007772268.1\|430956_431160_+	cold shock protein CspA	A0A1X9IGI9	Lactococcus_phage	8.9e-15	57.8
WP_014378961.1\|431320_431911_+	hypothetical protein	NA	NA	NA	NA
WP_014378962.1\|432114_434928_+	type I DNA topoisomerase	A0A2K9L5F8	Tupanvirus	9.6e-99	32.2
WP_029385090.1\|434924_436586_-	adenylate/guanylate cyclase domain-containing protein	A0A1B1IWY2	uncultured_Mediterranean_phage	1.7e-18	32.8

DBSCAN-SWA_36

439844 : 444898

Cafeteria_roenbergensis_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085981097.1\|439844_440789_+	GDP-mannose 4,6-dehydratase	E3T4Y8	Cafeteria_roenbergensis_virus	2.2e-31	30.9
WP_009953616.1\|440785_441127_-	DUF2304 domain-containing protein	NA	NA	NA	NA
WP_014378965.1\|441123_441822_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_014378966.1\|441857_443108_-	hypothetical protein	NA	NA	NA	NA
WP_014378967.1\|443232_444303_+	DUF475 domain-containing protein	A0A172Q0Y5	Acinetobacter_phage	1.7e-56	40.7
WP_008263447.1\|444409_444898_-	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	1.6e-30	46.1

DBSCAN-SWA_37

448442 : 449054

Hokovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263453.1\|448442_449054_+	hypoxanthine phosphoribosyltransferase	A0A1V0SEQ1	Hokovirus	3.5e-06	25.7

DBSCAN-SWA_38

458532 : 462432

Bathycoccus_sp._RCC1105_virus(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014378980.1\|458532_460965_+\|protease	ATP-dependent zinc metalloprotease FtsH	E5ESM9	Bathycoccus_sp._RCC1105_virus	4.4e-100	41.3
WP_014378981.1\|460981_461584_+	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	1.5e-46	54.1
WP_085976422.1\|461580_462432_+	dihydropteroate synthase	S4VNV0	Pandoravirus	9.2e-21	32.7

DBSCAN-SWA_39

468632 : 473476

Tupanvirus(33.33%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263500.1\|468632_470129_+\|tRNA	lysine--tRNA ligase	A0A2K9KZX5	Tupanvirus	1.9e-74	37.1
WP_008263502.1\|470256_470595_+	iron-regulated nucleoid-associated protein Lsr2	A0A2D1GPL8	Mycobacterium_phage	3.5e-16	41.5
WP_014378990.1\|470932_473476_+\|protease	ATP-dependent protease ATP-binding subunit ClpC	K4FB40	Cronobacter_phage	5.2e-128	39.4

DBSCAN-SWA_40

483597 : 485007

Catovirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071448.1\|483597_485007_+\|tRNA	cysteine--tRNA ligase	A0A1V0SAQ2	Catovirus	3.5e-41	27.1

DBSCAN-SWA_41

491429 : 492251

Pithovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957017.1\|491429_492251_-	metal ABC transporter ATP-binding protein	W5SAS9	Pithovirus	4.9e-11	26.8

DBSCAN-SWA_42

509648 : 511184

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379012.1\|509648_511184_-	fatty acid--CoA ligase family protein	Q75ZG1	Hepacivirus	7.9e-39	26.9

DBSCAN-SWA_43

520845 : 521751

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263643.1\|520845_521751_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	7.8e-10	28.2

DBSCAN-SWA_44

534994 : 535927

Ostreococcus_lucimarinus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014710858.1\|534994_535927_+	acetaldehyde dehydrogenase (acetylating)	G9E526	Ostreococcus_lucimarinus_virus	1.6e-34	32.9

DBSCAN-SWA_45

551755 : 556614

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263720.1\|551755_553408_+	acyl-CoA synthetase	A0A2H4PQM9	Staphylococcus_phage	6.0e-16	23.8
WP_014379044.1\|553438_554206_+	fructosamine kinase family protein	NA	NA	NA	NA
WP_014379045.1\|554242_555067_+	amidohydrolase	NA	NA	NA	NA
WP_014379046.1\|555063_556614_+	acetolactate synthase large subunit	E5EQ70	Micromonas_sp._RCC1109_virus	2.5e-08	32.6

DBSCAN-SWA_46

590260 : 596932

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379067.1\|590260_590980_+	two-component system response regulator PhoP	W8CYM9	Bacillus_phage	3.6e-34	36.3
WP_014381773.1\|591020_592463_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	9.2e-21	29.5
WP_009951974.1\|592450_592855_-	HIT family protein	NA	NA	NA	NA
WP_009951973.1\|592861_593299_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_008263811.1\|593487_594615_-	NDMA-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	1.2e-28	27.6
WP_008263812.1\|594815_595355_-	hypothetical protein	NA	NA	NA	NA
WP_008263814.1\|595357_595567_-	ferredoxin	NA	NA	NA	NA
WP_014379070.1\|595579_596932_-	cytochrome P450	M1PWN0	Moumouvirus	5.6e-12	27.4

DBSCAN-SWA_47

614828 : 617854

Mollivirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379083.1\|614828_615719_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	3.4e-42	37.0
WP_009951944.1\|615715_617854_+	S9 family peptidase	A0A1V0SHT0	Klosneuvirus	8.8e-28	27.1

DBSCAN-SWA_48

628589 : 629672

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379088.1\|628589_629672_+	NAD(P)-dependent oxidoreductase	A0A0E3FNQ3	Synechococcus_phage	3.3e-07	30.9

DBSCAN-SWA_49

641113 : 642127

Mollivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009951920.1\|641113_642127_-	Dyp-type peroxidase	A0A0M5KAH8	Mollivirus	1.1e-20	33.3

DBSCAN-SWA_50

645765 : 653183

Microbacterium_phage(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085977660.1\|645765_648087_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.6e-272	63.4
WP_193375131.1\|648106_648745_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_014379100.1\|648734_649949_-	MCE family protein	NA	NA	NA	NA
WP_009955028.1\|649968_650358_+	hypothetical protein	NA	NA	NA	NA
WP_008263903.1\|650495_652022_+	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	2.3e-46	29.9
WP_009955025.1\|652088_653183_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	7.9e-57	37.9

DBSCAN-SWA_51

660290 : 666053

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379102.1\|660290_661079_+	response regulator transcription factor	W8CYM9	Bacillus_phage	9.1e-15	32.5
WP_009955014.1\|661075_662005_+	mycothiol synthase	NA	NA	NA	NA
WP_014379103.1\|662142_663294_+	phosphate ABC transporter substrate-binding protein PstS	M4QRU1	Synechococcus_phage	1.9e-21	26.7
WP_041784786.1\|663309_664353_+	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_014379105.1\|664349_665264_+	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_008263919.1\|665276_666053_+	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-16	34.0

DBSCAN-SWA_52

673500 : 677176

Streptococcus_phage(33.33%)

integrase

attL 669803:669816|attR 678962:678975

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
669803:669816	attL	NA	NA	NA	NA
WP_014379112.1\|673500_673899_-	helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	7.9e-07	30.4
WP_014379113.1\|673944_674445_-	nucleoside deaminase	S4VYZ2	Pandoravirus	8.1e-09	39.2
WP_014379114.1\|674564_675464_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_041787011.1\|676018_677176_-\|integrase	site-specific integrase	A0A0E3XBN7	Gordonia_phage	2.1e-31	29.8
678962:678975	attR	NA	NA	NA	NA

DBSCAN-SWA_53

696964 : 697789

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379132.1\|696964_697789_-	NAD(P)-dependent oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	3.3e-07	27.5

DBSCAN-SWA_54

704685 : 706556

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379137.1\|704685_705024_-	2Fe-2S iron-sulfur cluster binding domain-containing protein	A0A222YX16	Synechococcus_phage	1.1e-06	34.3
WP_009954406.1\|705149_706556_+	acyl--CoA ligase	Q75ZG1	Hepacivirus	1.2e-36	32.5

DBSCAN-SWA_55

717136 : 719581

Only_Syngen_Nebraska_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014710968.1\|717136_717892_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.5e-14	27.1
WP_009954395.1\|717964_719581_-	FAD-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	1.8e-25	27.6

DBSCAN-SWA_56

723872 : 725600

Lactobacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379146.1\|723872_725600_+	FAD-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	2.1e-19	23.9

DBSCAN-SWA_57

728747 : 731990

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379149.1\|728747_729569_+	alpha/beta fold hydrolase	A0A249XTU1	Mycobacterium_phage	8.9e-05	25.9
WP_148278288.1\|729573_731178_-	multicopper oxidase family protein	NA	NA	NA	NA
WP_008253618.1\|731267_731990_-	SDR family oxidoreductase	A0A0G2Y8L6	Acanthamoeba_polyphaga_mimivirus	3.2e-06	32.3

DBSCAN-SWA_58

735824 : 736634

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379153.1\|735824_736634_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.2e-17	30.4

DBSCAN-SWA_59

797437 : 798556

Staphylococcus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_142305508.1\|797437_798556_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.1e-35	32.6

DBSCAN-SWA_60

827267 : 828671

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379214.1\|827267_828671_+	fatty acid--CoA ligase family protein	A0A1V0SBX8	Catovirus	3.0e-16	27.1

DBSCAN-SWA_61

846609 : 848259

Acidianus_filamentous_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379227.1\|846609_848259_-	DEAD/DEAH box helicase	B2CRJ8	Acidianus_filamentous_virus	2.7e-16	23.1

DBSCAN-SWA_62

852422 : 856001

Macacine_betaherpesvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379230.1\|852422_853217_-	transglycosylase family protein	A0A2I6B0Z0	Macacine_betaherpesvirus	1.5e-04	63.2
WP_009957587.1\|853646_853925_-	MoaD/ThiS family protein	NA	NA	NA	NA
WP_009957586.1\|853929_855024_-	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
WP_009957585.1\|855020_855428_-	YccF domain-containing protein	NA	NA	NA	NA
WP_008253852.1\|855593_856001_+	cold-shock protein	Q9AZD3	Lactococcus_phage	1.3e-09	46.0

DBSCAN-SWA_63

885142 : 887530

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379251.1\|885142_887530_+	cation-translocating P-type ATPase	M1HN09	Paramecium_bursaria_Chlorella_virus	9.2e-26	25.5

DBSCAN-SWA_64

909952 : 914251

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379266.1\|909952_910882_-	Ku protein	A0A249XRB2	Mycobacterium_phage	3.5e-66	50.0
WP_009953048.1\|911036_911960_-	carbohydrate kinase	NA	NA	NA	NA
WP_014379267.1\|911971_914251_+	ATP-dependent DNA ligase	A0A291AUP8	Sinorhizobium_phage	1.7e-37	35.6

DBSCAN-SWA_65

927474 : 933954

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379277.1\|927474_929817_+	DNA helicase PcrA	A7KV33	Bacillus_phage	8.5e-117	36.8
WP_193375134.1\|929901_930492_-	hypothetical protein	NA	NA	NA	NA
WP_014379278.1\|930493_931546_-	M23 family metallopeptidase	A0A2D1G842	Mycobacterium_phage	9.6e-20	43.4
WP_009957827.1\|931875_933039_+	ADP-forming succinate--CoA ligase subunit beta	NA	NA	NA	NA
WP_008254012.1\|933051_933954_+	succinate--CoA ligase subunit alpha	A0A2K9L5E9	Tupanvirus	2.6e-13	31.8

DBSCAN-SWA_66

939260 : 941487

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254024.1\|939260_939890_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.8e-20	35.4
WP_008254027.1\|939903_941487_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	3.1e-54	41.9

DBSCAN-SWA_67

945681 : 946530

Indivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379282.1\|945681_946530_+	aldo/keto reductase	A0A1V0SDE7	Indivirus	5.9e-36	30.7

DBSCAN-SWA_68

956308 : 960101

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254065.1\|956308_956995_+	two-component system response regulator MrpA	W8CYM9	Bacillus_phage	1.3e-36	38.7
WP_036397793.1\|957011_958574_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	2.4e-19	28.3
WP_029385689.1\|958646_960101_+	trypsin-like peptidase domain-containing protein	W5SAB9	Pithovirus	1.1e-05	34.1

DBSCAN-SWA_69

963266 : 964178

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254094.1\|963266_964178_+	UTP--glucose-1-phosphate uridylyltransferase	A0A127AW70	Bacillus_phage	2.6e-45	39.2

DBSCAN-SWA_70

971738 : 973037

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080552582.1\|971738_973037_+	cytochrome P450	V5UQK0	Mycobacterium_phage	3.2e-17	23.5

DBSCAN-SWA_71

977299 : 978921

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957791.1\|977299_978316_+	GHMP kinase	A0A222YW25	Synechococcus_phage	1.6e-56	39.2
WP_029385684.1\|978303_978921_+	SIS domain-containing protein	A0A067XQR2	Caulobacter_phage	2.2e-11	33.3

DBSCAN-SWA_72

982423 : 983020

Pacmanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954975.1\|982423_983020_-	alpha-ketoglutarate-dependent dioxygenase AlkB	A0A1X6WG33	Pacmanvirus	2.5e-09	30.4

DBSCAN-SWA_73

986907 : 988164

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379306.1\|986907_988164_-	aminodeoxychorismate synthase component I	S4VT78	Pandoravirus	7.9e-37	39.4

DBSCAN-SWA_74

994345 : 995140

Ostreococcus_mediterraneus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955586.1\|994345_995140_-	FkbM family methyltransferase	A0A0P0C5Z9	Ostreococcus_mediterraneus_virus	9.9e-09	34.0

DBSCAN-SWA_75

1002178 : 1003876

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379312.1\|1002178_1003876_+	GMC family oxidoreductase	A0A1V0S9J5	Catovirus	2.0e-06	45.3

DBSCAN-SWA_76

1013090 : 1013663

Enterobacteria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254170.1\|1013090_1013663_-	dTDP-4-dehydrorhamnose 3,5-epimerase family protein	I7HJC4	Enterobacteria_phage	1.2e-13	32.2

DBSCAN-SWA_77

1021225 : 1024926

Hokovirus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379324.1\|1021225_1022770_-\|tRNA	methionine--tRNA ligase	A0A1V0SEZ7	Hokovirus	6.2e-100	39.0
WP_026071421.1\|1022788_1023631_+	TatD family hydrolase	NA	NA	NA	NA
WP_014379326.1\|1023837_1024926_+	resuscitation-promoting factor	Q856D9	Mycobacterium_phage	2.6e-20	57.1

DBSCAN-SWA_78

1036907 : 1038233

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254208.1\|1036907_1037252_-	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	4.4e-30	57.8
WP_008254209.1\|1037252_1038233_-	ribose-phosphate diphosphokinase	A0A2H4UV84	Bodo_saltans_virus	8.1e-45	34.7

DBSCAN-SWA_79

1048142 : 1052720

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379340.1\|1048142_1049435_+	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	4.7e-133	55.7
WP_014379341.1\|1049436_1050138_+	septum formation initiator family protein	NA	NA	NA	NA
WP_009954138.1\|1050130_1050619_+	DUF501 domain-containing protein	NA	NA	NA	NA
WP_041787031.1\|1050612_1051563_+	Ppx/GppA family phosphatase	NA	NA	NA	NA
WP_014379343.1\|1051674_1051980_+	hypothetical protein	NA	NA	NA	NA
WP_009954135.1\|1052039_1052720_-	response regulator	W8CYM9	Bacillus_phage	5.8e-26	31.7

DBSCAN-SWA_80

1056234 : 1058385

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379345.1\|1056234_1058385_-	potassium-transporting ATPase subunit KdpB	M1HBF8	Paramecium_bursaria_Chlorella_virus	2.4e-25	24.7

DBSCAN-SWA_81

1061916 : 1062690

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954125.1\|1061916_1062690_-	response regulator transcription factor	W8CYM9	Bacillus_phage	9.5e-33	35.9

DBSCAN-SWA_82

1067747 : 1069938

Mycobacterium_phage(50.0%)

integrase

attL 1066178:1066225|attR 1078500:1078547

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1066178:1066225	attL	NA	NA	NA	NA
WP_041787033.1\|1067747_1069109_-\|integrase	site-specific integrase	R4JGJ2	Mycobacterium_phage	1.1e-15	26.8
WP_014379353.1\|1069108_1069291_-	hypothetical protein	NA	NA	NA	NA
WP_080587918.1\|1069287_1069938_-	recombinase family protein	A0A1W5LU24	Ralstonia_phage	1.7e-14	38.0
1078500:1078547	attR	NA	NA	NA	NA

DBSCAN-SWA_83

1083652 : 1086883

Staphylococcus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_179293485.1\|1083652_1084771_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	3.9e-35	32.8
WP_014379368.1\|1085251_1086883_+	fatty acid--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	2.7e-29	23.5

DBSCAN-SWA_84

1097886 : 1099005

Staphylococcus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_179293485.1\|1097886_1099005_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	3.9e-35	32.8

DBSCAN-SWA_85

1102713 : 1106144

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954593.1\|1102713_1104120_+	cystathionine beta-synthase	A0A1X9I5K7	Streptococcus_phage	1.3e-56	41.1
WP_009954594.1\|1104231_1104966_+	RDD family protein	NA	NA	NA	NA
WP_009954595.1\|1104977_1106144_+	cystathionine gamma-synthase	A0A0B5JD48	Pandoravirus	2.5e-24	33.2

DBSCAN-SWA_86

1112146 : 1120785

Flavobacterium_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254334.1\|1112146_1112935_+	isoprenyl transferase	R9W0U9	Flavobacterium_phage	1.2e-14	36.7
WP_014379379.1\|1113083_1113509_+	hypothetical protein	NA	NA	NA	NA
WP_008254336.1\|1113515_1114454_-	type I pantothenate kinase	NA	NA	NA	NA
WP_009953456.1\|1114569_1115850_+	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	1.0e-84	47.5
WP_008254339.1\|1115946_1116774_+	acyl-ACP desaturase	NA	NA	NA	NA
WP_008254341.1\|1117015_1118317_+	PhoH family protein	A0A2L0UZX2	Agrobacterium_phage	1.0e-23	31.2
WP_009953454.1\|1118405_1119281_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_008254355.1\|1119330_1120785_+	adenylate/guanylate cyclase domain-containing protein	A0A1B1IWY2	uncultured_Mediterranean_phage	3.8e-14	28.6

DBSCAN-SWA_87

1127363 : 1134914

Tupanvirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080587920.1\|1127363_1130645_+	non-ribosomal peptide synthetase	A0A2K9L3I8	Tupanvirus	5.4e-61	30.7
WP_009953447.1\|1130704_1132249_+	carboxylesterase/lipase family protein	M1PNU1	Moumouvirus	1.1e-32	33.2
WP_009953446.1\|1132245_1133346_-	NAD-dependent epimerase/dehydratase family protein	Q76TT0	Molluscum_contagiosum_virus	3.5e-28	32.1
WP_085976478.1\|1133407_1133620_-	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_009953445.1\|1133666_1134914_-	exodeoxyribonuclease VII large subunit	A0A1B3AYB4	Gordonia_phage	5.8e-72	51.5

DBSCAN-SWA_88

1142737 : 1149316

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085977620.1\|1142737_1143313_+	C40 family peptidase	A0A0K2FNG4	Mycobacterium_phage	7.9e-08	37.3
WP_009953431.1\|1143675_1143999_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_014384004.1\|1144047_1144731_-	hypothetical protein	NA	NA	NA	NA
WP_014381976.1\|1144877_1145087_+	hypothetical protein	NA	NA	NA	NA
WP_009953429.1\|1145038_1145872_-	adenylate/guanylate cyclase domain-containing protein	NA	NA	NA	NA
WP_009953427.1\|1145994_1147404_+	glucose-6-phosphate dehydrogenase	E3SJC5	Synechococcus_phage	1.2e-65	35.7
WP_009953426.1\|1147420_1148443_+	decarboxylating 6-phosphogluconate dehydrogenase	M1T2E7	Synechococcus_phage	2.9e-93	53.6
WP_008254400.1\|1148452_1149316_-	alpha/beta hydrolase	A0A0M4K6M8	Mollivirus	5.3e-08	29.8

DBSCAN-SWA_89

1152828 : 1154406

Stenotrophomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379393.1\|1152828_1154406_-	pyruvate, phosphate dikinase	A0A2D2W2B1	Stenotrophomonas_phage	4.9e-68	38.7

DBSCAN-SWA_90

1173721 : 1174582

Lake_Baikal_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379398.1\|1173721_1174582_+	CbbQ/NirQ/NorQ/GpvN family protein	A0A2H4N7N3	Lake_Baikal_phage	6.0e-12	27.5

DBSCAN-SWA_91

1195357 : 1196071

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041787036.1\|1195357_1196071_-	NAD-dependent deacylase	A0A068EPD4	Bacillus_phage	5.9e-21	32.2

DBSCAN-SWA_92

1207936 : 1209556

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379423.1\|1207936_1209556_+	nitrate reductase subunit beta	A0A077SL61	Escherichia_phage	8.7e-20	46.5

DBSCAN-SWA_93

1217288 : 1219880

Mamastrovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085977621.1\|1217288_1219880_+	bifunctional FO biosynthesis protein CofGH	A9ZMK9	Mamastrovirus	4.5e-18	35.8

DBSCAN-SWA_94

1235129 : 1237081

Moumouvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071439.1\|1235129_1235825_+	adenylyl-sulfate kinase	A0A2P1ELS9	Moumouvirus	3.9e-25	40.8
WP_014379437.1\|1235821_1237081_+	sulfate adenylyltransferase	A0A2K9L4R9	Tupanvirus	3.0e-28	28.4

DBSCAN-SWA_95

1245314 : 1248775

Staphylococcus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071442.1\|1245314_1246274_+	proline dehydrogenase family protein	A0A2H4PQT6	Staphylococcus_phage	2.3e-28	28.4
WP_193375144.1\|1247653_1248775_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	6.6e-35	32.6

DBSCAN-SWA_96

1254974 : 1256399

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379452.1\|1254974_1256399_+	acyl-CoA synthetase	Q75ZG1	Hepacivirus	3.0e-32	32.5

DBSCAN-SWA_97

1275339 : 1280837

Staphylococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041787038.1\|1275339_1276305_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.0e-20	28.5
WP_014379462.1\|1276294_1276933_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_014379463.1\|1277005_1277674_-	O-methyltransferase	NA	NA	NA	NA
WP_014379464.1\|1277875_1278631_+	RNA polymerase sigma factor SigE	A0A0F6TH34	Sinorhizobium_phage	2.1e-08	29.5
WP_041787176.1\|1278772_1279168_+	RNA polymerase subunit sigma-70	NA	NA	NA	NA
WP_009956301.1\|1279322_1280837_+	trypsin-like peptidase domain-containing protein	A0A1B1IRH0	uncultured_Mediterranean_phage	1.9e-08	32.2

DBSCAN-SWA_98

1290484 : 1291663

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957422.1\|1290484_1291663_+	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	3.8e-25	35.9

DBSCAN-SWA_99

1305608 : 1312642

Beihai_Nido-like_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379477.1\|1305608_1309040_-	TM0106 family RecB-like putative nuclease	A0A1L3KIW1	Beihai_Nido-like_virus	3.3e-08	25.9
WP_026071531.1\|1309100_1309682_-	LppP/LprE family lipoprotein	NA	NA	NA	NA
WP_009953174.1\|1309802_1311506_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.8e-53	34.9
WP_009953175.1\|1311502_1312642_+	acyltransferase	A0A1R3Y5Q6	Salmonella_virus	8.3e-09	25.2

DBSCAN-SWA_100

1326216 : 1327608

Pseudomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953188.1\|1326216_1327608_+	ATP-binding protein	A0A2K9VHR2	Pseudomonas_phage	7.2e-15	28.9

DBSCAN-SWA_101

1338446 : 1340826

Trichoplusia_ni_ascovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953203.1\|1338446_1339187_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	8.6e-15	28.3
WP_009953206.1\|1339179_1340826_+	AMP-binding protein	Q75ZG1	Hepacivirus	1.7e-23	24.6

DBSCAN-SWA_102

1356633 : 1357572

Acanthamoeba_polyphaga_mimivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953686.1\|1356633_1357572_-	alpha/beta hydrolase	A0A2L2DMU8	Acanthamoeba_polyphaga_mimivirus	1.5e-24	28.3

DBSCAN-SWA_103

1366605 : 1368012

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379500.1\|1366605_1368012_-	adenylate/guanylate cyclase domain-containing protein	A0A1B1IWY2	uncultured_Mediterranean_phage	3.5e-17	32.5

DBSCAN-SWA_104

1423808 : 1425308

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379521.1\|1423808_1425308_+	long-chain fatty acid--CoA ligase	Q75ZG1	Hepacivirus	2.0e-34	30.5

DBSCAN-SWA_105

1434921 : 1436484

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953790.1\|1434921_1436484_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	3.0e-33	26.4

DBSCAN-SWA_106

1445734 : 1447252

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379526.1\|1445734_1447252_+	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	2.1e-07	25.8

DBSCAN-SWA_107

1459788 : 1461396

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379531.1\|1459788_1461396_-	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	1.2e-24	26.8

DBSCAN-SWA_108

1485929 : 1487531

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379539.1\|1485929_1487531_+	AMP-binding protein	A0A1V0SBX8	Catovirus	1.9e-11	33.5

DBSCAN-SWA_109

1494478 : 1495612

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953864.1\|1494478_1495612_-	NDMA-dependent alcohol dehydrogenase	A0A2K9L339	Tupanvirus	1.2e-15	28.8

DBSCAN-SWA_110

1517658 : 1521550

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953892.1\|1517658_1519104_+	long-chain fatty acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.8e-29	26.6
WP_020415599.1\|1519404_1519797_+	DUF732 domain-containing protein	NA	NA	NA	NA
WP_009953895.1\|1520174_1520630_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_009953897.1\|1520827_1521550_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	1.0e-20	47.4

DBSCAN-SWA_111

1525447 : 1526380

Ostreococcus_lucimarinus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379550.1\|1525447_1526380_-	acetaldehyde dehydrogenase (acetylating)	G9E526	Ostreococcus_lucimarinus_virus	4.7e-34	31.8

DBSCAN-SWA_112

1574725 : 1578592

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379571.1\|1574725_1578592_-	bifunctional diguanylate cyclase/phosphodiesterase	G3MA91	Bacillus_virus	6.9e-07	31.2

DBSCAN-SWA_113

1583381 : 1589006

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254716.1\|1583381_1585148_-	sensor domain-containing protein	M1HTZ5	Acanthocystis_turfacea_Chlorella_virus	3.7e-16	31.2
WP_009953974.1\|1585326_1587243_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.3e-50	31.4
WP_009953975.1\|1587239_1589006_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.1e-39	26.3

DBSCAN-SWA_114

1597807 : 1599643

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955266.1\|1597807_1599643_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-16	32.2

DBSCAN-SWA_115

1603854 : 1605696

Noumeavirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254752.1\|1603854_1605696_+	adenylyl-sulfate kinase	A0A1Q1PNX7	Noumeavirus	3.4e-28	25.6

DBSCAN-SWA_116

1612472 : 1613156

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_029384887.1\|1612472_1613156_-	hypothetical protein	Q9ZX60	Mycobacterium_phage	7.1e-24	44.9

DBSCAN-SWA_117

1625042 : 1625702

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379592.1\|1625042_1625702_+	threonylcarbamoyl-AMP synthase	S4VW33	Pandoravirus	3.3e-18	36.3

DBSCAN-SWA_118

1646371 : 1652379

Mycobacterium_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254846.1\|1646371_1647085_-	hypothetical protein	A0A222ZL07	Mycobacterium_phage	1.5e-11	29.7
WP_008254847.1\|1647107_1647416_-	hypothetical protein	A0A1J0MBV8	Mycobacterium_phage	1.7e-17	49.0
WP_008254850.1\|1647477_1647969_-	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	9.1e-21	51.4
WP_009955327.1\|1647965_1649453_-	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_008254855.1\|1649666_1650740_+	GGDEF domain-containing protein	A0A2D0W9B6	Bordetella_phage	1.2e-09	44.7
WP_014379597.1\|1650753_1652379_-	adenylate/guanylate cyclase domain-containing protein	A0A1B1IWY2	uncultured_Mediterranean_phage	1.2e-13	30.4

DBSCAN-SWA_119

1663638 : 1666982

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085981102.1\|1663638_1665678_-	ATP-dependent DNA helicase	A0A127AW80	Bacillus_phage	5.4e-51	26.9
WP_014379604.1\|1665674_1666982_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	3.1e-44	35.4

DBSCAN-SWA_120

1672251 : 1679409

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_029384214.1\|1672251_1672869_+	RdgB/HAM1 family non-canonical purine NTP pyrophosphatase	Q66YC8	Euphorbia_ringspot_virus	3.1e-10	32.1
WP_009952852.1\|1673034_1673385_-	DUF3817 domain-containing protein	NA	NA	NA	NA
WP_026071506.1\|1673381_1673762_-	hypothetical protein	NA	NA	NA	NA
WP_009952855.1\|1674017_1674347_+	hypothetical protein	NA	NA	NA	NA
WP_009952856.1\|1674354_1674780_-	DUF393 domain-containing protein	NA	NA	NA	NA
WP_014379607.1\|1675051_1677667_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	3.7e-28	26.8
WP_009952859.1\|1677663_1679409_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.1e-23	28.3

DBSCAN-SWA_121

1686562 : 1687312

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254916.1\|1686562_1687312_+	3-oxoacyl-ACP reductase FabG	Q06VL0	Trichoplusia_ni_ascovirus	2.4e-09	25.5

DBSCAN-SWA_122

1694070 : 1695600

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952881.1\|1694070_1695600_-	acyl--CoA ligase	Q75ZG1	Hepacivirus	6.5e-17	24.0

DBSCAN-SWA_123

1725378 : 1726386

Aureococcus_anophage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957694.1\|1725378_1726386_-	Rieske (2Fe-2S) protein	A0A076FFT9	Aureococcus_anophage	3.1e-07	25.9

DBSCAN-SWA_124

1738298 : 1739456

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957681.1\|1738298_1739456_-	Zn-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	6.2e-36	30.0

DBSCAN-SWA_125

1749386 : 1750895

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008255024.1\|1749386_1750895_-	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	7.6e-26	30.6

DBSCAN-SWA_126

1763098 : 1764664

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379639.1\|1763098_1764664_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	2.3e-17	24.1

DBSCAN-SWA_127

1772237 : 1772960

Rhodococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957520.1\|1772237_1772960_+	DUF1906 domain-containing protein	A0A2P1JXS5	Rhodococcus_phage	2.5e-51	48.4

DBSCAN-SWA_128

1798527 : 1800945

Vibrio_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008255097.1\|1798527_1799175_-	oligoribonuclease	M4M9I5	Vibrio_phage	2.7e-25	42.1
WP_009957504.1\|1799376_1800945_+	DUF853 family protein	A0A248XCZ8	Klebsiella_phage	3.0e-57	36.1

DBSCAN-SWA_129

1805038 : 1806628

Pike_perch_iridovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_029385536.1\|1805038_1806628_+	methylcrotonoyl-CoA carboxylase	A0A1B2ITV7	Pike_perch_iridovirus	3.6e-18	61.1

DBSCAN-SWA_130

1817271 : 1818519

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382165.1\|1817271_1818519_+	alpha/beta hydrolase	A0A068F2G2	Mycobacterium_phage	1.5e-35	39.8

DBSCAN-SWA_131

1826735 : 1828960

Propionibacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955482.1\|1826735_1827206_+	single-stranded DNA-binding protein	A0A1D8ETH0	Propionibacterium_phage	4.2e-15	36.7
WP_009955480.1\|1827283_1828960_+	energy-dependent translational throttle protein EttA	A0A2K9L3Z8	Tupanvirus	3.4e-43	27.2

DBSCAN-SWA_132

1838265 : 1844299

Cyanophage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071535.1\|1838265_1838916_+	HNH endonuclease	H6WG01	Cyanophage	1.5e-18	34.9
WP_008255162.1\|1838983_1839211_+	hypothetical protein	NA	NA	NA	NA
WP_008255165.1\|1839197_1839665_+	DUF5130 domain-containing protein	NA	NA	NA	NA
WP_014379669.1\|1839665_1842239_-	aminopeptidase N	A0A2K9L1R3	Tupanvirus	1.3e-46	31.6
WP_008255169.1\|1842330_1842954_+	DsbA family protein	NA	NA	NA	NA
WP_014379670.1\|1842994_1843474_+	ribose-5-phosphate isomerase	NA	NA	NA	NA
WP_009955466.1\|1843492_1844299_+	Fpg/Nei family DNA glycosylase	A0A1V0CNR6	Kaumoebavirus	5.3e-10	24.9

DBSCAN-SWA_133

1847832 : 1852941

Agrobacterium_phage(25.0%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008255177.1\|1847832_1848423_+\|protease	ATP-dependent CLP protease proteolytic subunit ClpP1	A0A223W000	Agrobacterium_phage	4.7e-40	47.5
WP_008255179.1\|1848419_1849055_+\|protease	ATP-dependent CLP protease proteolytic subunit ClpP2	A0A2H4JEX1	uncultured_Caudovirales_phage	3.3e-07	31.8
WP_179293485.1\|1849102_1850221_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	3.9e-35	32.8
WP_014379673.1\|1850374_1851319_-	homocysteine S-methyltransferase	NA	NA	NA	NA
WP_008255183.1\|1851660_1852941_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	2.4e-142	60.2

DBSCAN-SWA_134

1858224 : 1865104

Streptomyces_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071537.1\|1858224_1858779_+	transglycosylase family protein	A0A1J0GVU2	Streptomyces_phage	5.2e-25	79.7
WP_014379678.1\|1858892_1860152_+	saccharopine dehydrogenase NADP-binding domain-containing protein	NA	NA	NA	NA
WP_009955949.1\|1860210_1862859_+\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	6.0e-143	40.0
WP_009955948.1\|1862855_1864325_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_008255199.1\|1864321_1864672_+	DUF4233 domain-containing protein	NA	NA	NA	NA
WP_009955946.1\|1864693_1865104_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	3.7e-28	50.0

DBSCAN-SWA_135

1870674 : 1871778

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953574.1\|1870674_1871778_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	4.8e-54	38.2

DBSCAN-SWA_136

1882047 : 1883331

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071540.1\|1882047_1883331_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	2.9e-95	50.8

DBSCAN-SWA_137

1895721 : 1896849

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953593.1\|1895721_1896849_-	PE-PPE domain-containing protein	A0A222ZKN7	Mycobacterium_phage	1.4e-21	35.5

DBSCAN-SWA_138

1901754 : 1912779

Paenibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379696.1\|1901754_1912779_+	type I polyketide synthase	D0R7J2	Paenibacillus_phage	8.3e-29	27.5

DBSCAN-SWA_139

1927024 : 1928896

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080587926.1\|1927024_1928896_+	elongation factor 4	A0A2K9L6L3	Tupanvirus	3.1e-21	40.5

DBSCAN-SWA_140

1935878 : 1936961

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952315.1\|1935878_1936961_+	sulfate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	9.9e-28	38.4

DBSCAN-SWA_141

1950417 : 1951281

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956558.1\|1950417_1951281_+	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	8.1e-33	32.5

DBSCAN-SWA_142

1957490 : 1962585

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379719.1\|1957490_1959044_+	GMC family oxidoreductase N-terminal domain-containing protein	A0A1V0S9M4	Catovirus	1.9e-48	29.2
WP_036458584.1\|1959791_1961411_+	OB-fold domain-containing protein	NA	NA	NA	NA
WP_009956544.1\|1961421_1962585_-	NDMA-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	3.9e-30	28.3

DBSCAN-SWA_143

2010042 : 2011506

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956483.1\|2010042_2011506_-	acyl--CoA ligase	Q75ZG1	Hepacivirus	2.9e-22	23.8

DBSCAN-SWA_144

2023496 : 2024576

Acanthocystis_turfacea_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008255445.1\|2023496_2024576_+	hydroxyacid dehydrogenase	M1HUT5	Acanthocystis_turfacea_Chlorella_virus	5.1e-24	31.1

DBSCAN-SWA_145

2043540 : 2044161

Macacine_betaherpesvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_052315298.1\|2043540_2044161_-	hypothetical protein	A0A2I6B2H4	Macacine_betaherpesvirus	2.7e-30	43.9

DBSCAN-SWA_146

2047327 : 2048098

Niemeyer_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009976204.1\|2047327_2048098_-	slipin family protein	A0A0U2UF06	Niemeyer_virus	1.8e-23	28.3

DBSCAN-SWA_147

2069128 : 2075572

Escherichia_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379791.1\|2069128_2070196_+	3-deoxy-7-phosphoheptulonate synthase	A0A060BHG3	Escherichia_phage	1.4e-82	48.1
WP_014379792.1\|2070335_2071973_-	AMP-binding protein	A0A1V0SBX8	Catovirus	3.5e-08	37.2
WP_014379793.1\|2072068_2075572_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	6.0e-42	23.0

DBSCAN-SWA_148

2080724 : 2091736

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379795.1\|2080724_2087300_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	2.4e-124	24.4
WP_014379796.1\|2087296_2091736_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	5.3e-35	23.6

DBSCAN-SWA_149

2097956 : 2101052

Ectocarpus_siliculosus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008255583.1\|2097956_2099105_+	molecular chaperone DnaJ	Q8QNB4	Ectocarpus_siliculosus_virus	5.6e-29	30.4
WP_014379801.1\|2099118_2099880_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_029384281.1\|2099993_2101052_+	PhoH family protein	W8D063	Erwinia_phage	8.7e-45	44.8

DBSCAN-SWA_150

2109136 : 2112830

Flavobacterium_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953080.1\|2109136_2110006_+	decaprenyl diphosphate synthase	R9W0U9	Flavobacterium_phage	7.0e-16	40.5
WP_008255604.1\|2110005_2110434_+	hypothetical protein	NA	NA	NA	NA
WP_008255605.1\|2110437_2110833_-	transcriptional repressor	NA	NA	NA	NA
WP_192579485.1\|2110829_2111255_-	metalloregulator ArsR/SmtB family transcription factor	NA	NA	NA	NA
WP_008255621.1\|2111438_2112830_+\|tRNA	glycine--tRNA ligase	A0A2I2L3K8	Orpheovirus	1.7e-48	29.9

DBSCAN-SWA_151

2119205 : 2121158

Helicobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379813.1\|2119205_2121158_+	DNA primase	A0A1S5REW9	Helicobacter_phage	6.8e-35	31.7

DBSCAN-SWA_152

2126113 : 2127046

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008255646.1\|2126113_2127046_-	cysteine synthase A	A0A1X9I5K7	Streptococcus_phage	2.9e-84	53.4

DBSCAN-SWA_153

2135358 : 2142443

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379818.1\|2135358_2137311_-	acyl-CoA dehydrogenase family protein	A0A2K9L6M4	Tupanvirus	1.1e-53	30.2
WP_041787185.1\|2137360_2139694_-	ATP-binding cassette domain-containing protein	A0A2R8FG22	Brazilian_cedratvirus	3.1e-18	30.6
WP_009954612.1\|2139808_2140297_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_029384670.1\|2140460_2142443_+	ATP-binding cassette domain-containing protein	A0A2I4R674	Erysipelothrix_phage	5.7e-05	27.4

DBSCAN-SWA_154

2156916 : 2158092

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041787042.1\|2156916_2158092_-	hypothetical protein	S5Z967	Mycobacterium_phage	7.3e-85	43.5

DBSCAN-SWA_155

2162980 : 2170945

Ralstonia_phage(25.0%)

integrase

attL 2161715:2161728|attR 2165609:2165622

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2161715:2161728	attL	NA	NA	NA	NA
WP_168162067.1\|2162980_2163622_+	recombinase family protein	A0A1W5LU24	Ralstonia_phage	4.8e-14	37.4
WP_014379840.1\|2163621_2165031_+\|integrase	site-specific integrase	A0A0E3XBN7	Gordonia_phage	1.5e-12	27.3
WP_148278272.1\|2165027_2166236_-	hypothetical protein	NA	NA	NA	NA
2165609:2165622	attR	NA	NA	NA	NA
WP_052315300.1\|2166232_2166799_-	DUF4365 domain-containing protein	NA	NA	NA	NA
WP_014382320.1\|2167126_2168284_-	alpha/beta hydrolase	A0A1C9LYC8	Mycobacterium_phage	4.0e-43	42.2
WP_014379843.1\|2168398_2170945_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	4.4e-151	34.2

DBSCAN-SWA_156

2196896 : 2198831

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008255722.1\|2196896_2198831_+	molecular chaperone HtpG	A0A1V0SAD6	Catovirus	1.0e-107	34.3

DBSCAN-SWA_157

2202119 : 2203250

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379861.1\|2202119_2203250_-	NDMA-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	1.8e-27	29.0

DBSCAN-SWA_158

2222812 : 2224321

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952270.1\|2222812_2224321_+	ACR3 family arsenite efflux transporter	A0A2H4PQT9	Staphylococcus_phage	1.2e-10	34.7

DBSCAN-SWA_159

2232801 : 2233980

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952259.1\|2232801_2233980_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	2.0e-58	36.7

DBSCAN-SWA_160

2241805 : 2242798

Orpheovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379888.1\|2241805_2242798_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	3.1e-68	47.2

DBSCAN-SWA_161

2248471 : 2249953

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952243.1\|2248471_2249953_+	serine/threonine protein kinase	M1HUJ3	Paramecium_bursaria_Chlorella_virus	8.0e-12	28.1

DBSCAN-SWA_162

2254351 : 2259079

Leptospira_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379898.1\|2254351_2257453_+	DUF3427 domain-containing protein	Q6NDX2	Leptospira_phage	5.9e-33	30.4
WP_014379899.1\|2257513_2259079_-	serine/threonine protein kinase	M1I231	Acanthocystis_turfacea_Chlorella_virus	2.1e-18	29.3

DBSCAN-SWA_163

2274082 : 2275168

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041787048.1\|2274082_2275168_-	S-(hydroxymethyl)mycothiol dehydrogenase	E3SJ82	Synechococcus_phage	4.8e-30	29.2

DBSCAN-SWA_164

2304696 : 2307682

Agrobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379931.1\|2304696_2305836_+	bifunctional RNase H/acid phosphatase	A0A2L0V0T1	Agrobacterium_phage	3.0e-06	30.8
WP_014379932.1\|2305824_2306229_-	VOC family protein	NA	NA	NA	NA
WP_014379933.1\|2306182_2307025_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_014379934.1\|2307109_2307682_-	helix-turn-helix domain-containing protein	F8TVE5	EBPR_siphovirus	9.6e-06	46.5

DBSCAN-SWA_165

2338378 : 2339926

Mycoplasma_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_036455196.1\|2338378_2339926_-	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	6.1e-31	33.9

DBSCAN-SWA_166

2345582 : 2352437

Streptococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008256049.1\|2345582_2346659_+	glycerate kinase	W6LM47	Streptococcus_phage	6.6e-16	29.7
WP_008256050.1\|2346738_2347095_+	iron-sulfur cluster assembly accessory protein	NA	NA	NA	NA
WP_014379954.1\|2347173_2347860_-	hypothetical protein	NA	NA	NA	NA
WP_009957664.1\|2348043_2349018_+	carbohydrate kinase family protein	NA	NA	NA	NA
WP_179293485.1\|2349293_2350412_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	3.9e-35	32.8
WP_014379955.1\|2350478_2352437_-	asparagine synthase (glutamine-hydrolyzing)	I3UKG6	Ostreococcus_lucimarinus_virus	1.9e-21	28.3

DBSCAN-SWA_167

2361566 : 2369066

Clostridium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_036458799.1\|2361566_2363498_-	DEDD exonuclease domain-containing protein	A0A0K2SUJ2	Clostridium_phage	5.7e-10	31.4
WP_170320588.1\|2363665_2363860_+	hypothetical protein	NA	NA	NA	NA
WP_041787051.1\|2364039_2365191_+	C40 family peptidase	A0A1J0GW44	Streptomyces_phage	1.1e-16	41.4
WP_009953495.1\|2365249_2366065_+	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_009953493.1\|2366120_2367251_+	GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase	NA	NA	NA	NA
WP_014379960.1\|2367263_2369066_-	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	8.1e-51	27.2

DBSCAN-SWA_168

2374875 : 2378129

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008256110.1\|2374875_2375370_+	polyadenylate-specific 3'-exoribonuclease AS	A0A249XQ39	Mycobacterium_phage	2.9e-27	43.2
WP_008256111.1\|2375444_2376833_+	3-deoxy-7-phosphoheptulonate synthase class II	NA	NA	NA	NA
WP_179293439.1\|2376839_2378129_-	protein kinase	S4W2F5	Pandoravirus	3.8e-18	35.4

DBSCAN-SWA_169

2414576 : 2416904

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085981087.1\|2414576_2416904_+	copper-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	7.9e-91	33.8

DBSCAN-SWA_170

2422966 : 2425222

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379987.1\|2422966_2425222_-	manganese-exporting P-type ATPase CtpC	E4ZFI9	Streptococcus_phage	4.5e-75	32.2

DBSCAN-SWA_171

2430664 : 2433031

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085981105.1\|2430664_2433031_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	6.8e-90	38.2

DBSCAN-SWA_172

2449420 : 2450656

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008256229.1\|2449420_2450656_+	cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase	A0A1V0SAQ2	Catovirus	2.1e-26	25.1

DBSCAN-SWA_173

2457687 : 2477030

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168162061.1\|2457687_2475522_+	amino acid adenylation domain-containing protein	A0A2K9KZV5	Tupanvirus	3.8e-148	26.9
WP_044059212.1\|2475521_2477030_+	MFS transporter	A0A0M3UL24	Mycobacterium_phage	6.6e-38	32.7

DBSCAN-SWA_174

2492557 : 2496352

Dickeya_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380026.1\|2492557_2496352_+	methionine synthase	A0A140XBC7	Dickeya_phage	2.6e-14	56.5

DBSCAN-SWA_175

2514343 : 2516173

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008256304.1\|2514343_2516173_+	proteasome ATPase	A0A2K9L596	Tupanvirus	2.7e-33	35.4

DBSCAN-SWA_176

2527239 : 2531811

Acanthocystis_turfacea_Chlorella_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953367.1\|2527239_2530020_+	RNA helicase	M1ILW8	Acanthocystis_turfacea_Chlorella_virus	9.2e-70	34.2
WP_009953366.1\|2530085_2530847_+	DUF4333 domain-containing protein	NA	NA	NA	NA
WP_009953362.1\|2530854_2531811_-	5'-3' exonuclease	A0A2P1JXG8	Rhodococcus_phage	3.4e-24	35.5

DBSCAN-SWA_177

2544534 : 2545290

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380045.1\|2544534_2545290_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.9e-24	32.0

DBSCAN-SWA_178

2557366 : 2571924

Sulfolobus_monocaudavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008256379.1\|2557366_2558161_+	polyprenol monophosphomannose synthase	A0A0N7A8R9	Sulfolobus_monocaudavirus	7.5e-25	39.3
WP_007770897.1\|2558170_2558506_-	RNA polymerase-binding protein RbpA	NA	NA	NA	NA
WP_026071594.1\|2558678_2559029_+	hypothetical protein	NA	NA	NA	NA
WP_041787193.1\|2559390_2571924_+	type I polyketide synthase	D0R7J2	Paenibacillus_phage	4.4e-26	31.4

DBSCAN-SWA_179

2587230 : 2588049

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_029385275.1\|2587230_2588049_+	mycofactocin-coupled SDR family oxidoreductase	W8CYX9	Bacillus_phage	1.6e-09	42.9

DBSCAN-SWA_180

2591561 : 2593079

Mollivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041787059.1\|2591561_2593079_+	carboxylesterase/lipase family protein	A0A0M4JT58	Mollivirus	3.1e-27	31.6

DBSCAN-SWA_181

2599820 : 2600381

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380065.1\|2599820_2600381_+	pyrazinamidase PncA	A0A1V0SL12	Klosneuvirus	6.5e-07	24.7

DBSCAN-SWA_182

2605814 : 2607917

Planktothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008256437.1\|2605814_2606885_+	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	1.0e-21	30.3
WP_009956368.1\|2606951_2607917_+	patatin-like phospholipase family protein	A0A0H3TN97	Faustovirus	3.1e-17	26.7

DBSCAN-SWA_183

2627219 : 2628011

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380088.1\|2627219_2628011_+	glucose 1-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	5.4e-15	31.7

DBSCAN-SWA_184

2638951 : 2639779

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380096.1\|2638951_2639779_+	DUF1906 domain-containing protein	A0A1B3B0M0	Gordonia_phage	6.8e-53	46.4

DBSCAN-SWA_185

2659929 : 2660664

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954576.1\|2659929_2660664_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.2e-22	31.6

DBSCAN-SWA_186

2670431 : 2671193

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008256611.1\|2670431_2671193_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	6.1e-16	32.2

DBSCAN-SWA_187

2676370 : 2677870

Cyanophage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380122.1\|2676370_2677870_-	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	2.4e-72	35.8

DBSCAN-SWA_188

2680880 : 2684798

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957164.1\|2680880_2684798_-	ATP-dependent RNA helicase HrpA	A0A1V0SIV3	Klosneuvirus	1.1e-36	24.6

DBSCAN-SWA_189

2704628 : 2705426

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380139.1\|2704628_2705426_-	DUF1906 domain-containing protein	A0A2D1GEF2	Gordonia_phage	3.7e-56	49.8

DBSCAN-SWA_190

2725207 : 2727990

Trichoplusia_ni_ascovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954866.1\|2725207_2725978_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.8e-15	32.9
WP_014380143.1\|2725985_2726663_-	hypothetical protein	NA	NA	NA	NA
WP_009956985.1\|2726892_2727990_-	EstA family serine hydrolase	A0A2K9L1U3	Tupanvirus	3.6e-25	31.6

DBSCAN-SWA_191

2748017 : 2751120

Burkholderia_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014384715.1\|2748017_2749292_+	MFS transporter	Q6JIH2	Burkholderia_virus	1.5e-14	26.6
WP_009956817.1\|2749295_2750591_-	competence/damage-inducible protein A	B5TK85	Pseudomonas_phage	6.1e-16	42.8
WP_029385352.1\|2750625_2751120_+	macro domain-containing protein	A0A0K1L687	Scale_drop_disease_virus	3.6e-09	31.9

DBSCAN-SWA_192

2759781 : 2765361

Macacine_betaherpesvirus(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956807.1\|2759781_2760795_+	alcohol dehydrogenase catalytic domain-containing protein	A0A0G2YAX3	Acanthamoeba_polyphaga_mimivirus	3.6e-32	28.6
WP_009956806.1\|2760807_2761368_+	YceI family protein	NA	NA	NA	NA
WP_026071387.1\|2761387_2762524_-	hypothetical protein	NA	NA	NA	NA
WP_009952996.1\|2763150_2764143_+	esterase family protein	A0A2I6B0H1	Macacine_betaherpesvirus	4.9e-167	86.1
WP_014382592.1\|2764950_2765361_+	transglycosylase family protein	A0A2I6B0Z0	Macacine_betaherpesvirus	8.0e-47	69.4

DBSCAN-SWA_193

2782159 : 2786291

Bodo_saltans_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953019.1\|2782159_2782597_-	DUF1810 domain-containing protein	A0A2H4UVK5	Bodo_saltans_virus	7.1e-17	40.2
WP_014382602.1\|2782616_2783876_+	alpha-hydroxy-acid oxidizing protein	NA	NA	NA	NA
WP_179293458.1\|2783969_2786291_+	endopeptidase La	A0A0R6PGP8	Moraxella_phage	1.6e-144	40.5

DBSCAN-SWA_194

2804056 : 2805160

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380167.1\|2804056_2805160_-	sulfate/molybdate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.5e-18	34.7

DBSCAN-SWA_195

2813018 : 2815964

Ostreococcus_lucimarinus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956145.1\|2813018_2814488_+	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	1.3e-33	25.7
WP_014380175.1\|2814527_2815964_+	GuaB1 family IMP dehydrogenase-related protein	A0A1V0SHK8	Klosneuvirus	1.8e-45	29.3

DBSCAN-SWA_196

2830094 : 2832917

Prochlorococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957612.1\|2830094_2832917_-	aminomethyl-transferring glycine dehydrogenase	M4QFZ1	Prochlorococcus_phage	2.4e-259	50.9

DBSCAN-SWA_197

2843575 : 2845495

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957620.1\|2843575_2845495_+	ABC transporter ATP-binding protein/permease	G3M9Y6	Bacillus_virus	1.5e-07	26.7

DBSCAN-SWA_198

2850778 : 2851495

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380185.1\|2850778_2851495_-	MgtC/SapB family protein	G3MA03	Bacillus_virus	5.6e-11	36.1

DBSCAN-SWA_199

2861193 : 2866062

Mycobacterium_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008257033.1\|2861193_2863023_-	type VII secretion system ESX-5 AAA family ATPase EccA5	V5UQM2	Mycobacterium_phage	3.7e-67	32.3
WP_014380194.1\|2863019_2864219_-	type VII secretion protein EccE	NA	NA	NA	NA
WP_008257037.1\|2864238_2866062_-\|protease	type VII secretion-associated serine protease mycosin	V5UPA7	Mycobacterium_phage	1.0e-72	35.3

DBSCAN-SWA_200

2878397 : 2882561

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954152.1\|2878397_2882561_-	type VII secretion protein EccC	V5UPA0	Mycobacterium_phage	9.2e-114	26.2

DBSCAN-SWA_201

2901601 : 2903137

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380209.1\|2901601_2903137_+	acyl-CoA synthetase	A0A2H4PQM9	Staphylococcus_phage	1.6e-26	23.4

DBSCAN-SWA_202

2909491 : 2910856

Chrysochromulina_ericina_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380215.1\|2909491_2910856_+	DEAD/DEAH box helicase	A0A0N9Q9J4	Chrysochromulina_ericina_virus	7.8e-38	28.7

DBSCAN-SWA_203

2917143 : 2917953

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_036396576.1\|2917143_2917953_+	SigB/SigF/SigG family RNA polymerase sigma factor	A0A0E3T5M9	Bacillus_phage	1.8e-18	30.6

DBSCAN-SWA_204

2947591 : 2949205

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952380.1\|2947591_2949205_-	acyl--CoA ligase	A0A1V0SBX8	Catovirus	3.4e-08	28.4

DBSCAN-SWA_205

2963644 : 2966341

Cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162130886.1\|2963644_2966341_-	ATP-binding cassette domain-containing protein	A0A2R8FFL6	Cedratvirus	7.9e-26	34.7

DBSCAN-SWA_206

2984061 : 2984985

Acanthamoeba_polyphaga_mimivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380254.1\|2984061_2984985_+	alpha/beta hydrolase	A0A0G2YDK2	Acanthamoeba_polyphaga_mimivirus	4.2e-35	36.9

DBSCAN-SWA_207

2988921 : 2990520

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085981108.1\|2988921_2990520_+	acyl-CoA synthetase	A0A2K9KZV5	Tupanvirus	1.5e-11	24.5

DBSCAN-SWA_208

3009688 : 3011470

Acanthocystis_turfacea_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014711780.1\|3009688_3011470_+	protein kinase	M1HKB5	Acanthocystis_turfacea_Chlorella_virus	3.4e-17	33.3

DBSCAN-SWA_209

3014813 : 3047965

Acanthamoeba_polyphaga_mimivirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041787067.1\|3014813_3016619_-	N-acetylglutaminylglutamine amidotransferase	A0A0G2Y369	Acanthamoeba_polyphaga_mimivirus	2.2e-27	25.2
WP_014380277.1\|3016714_3047965_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	1.7e-151	27.4

DBSCAN-SWA_210

3052976 : 3053180

Lactococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954002.1\|3052976_3053180_+	cold-shock protein	Q9AZD3	Lactococcus_phage	6.8e-15	56.9

DBSCAN-SWA_211

3062504 : 3062840

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_052315302.1\|3062504_3062840_-	hypothetical protein	A0A222ZLD7	Mycobacterium_phage	1.6e-40	77.8

DBSCAN-SWA_212

3066199 : 3073093

uncultured_Mediterranean_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071366.1\|3066199_3066880_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	2.7e-07	27.0
WP_008257548.1\|3067023_3067842_-	segregation/condensation protein A	NA	NA	NA	NA
WP_008257550.1\|3067838_3068702_-	ParA family protein	Q8JL10	Natrialba_phage	1.5e-23	36.9
WP_014380298.1\|3068936_3069686_+	O-methyltransferase	NA	NA	NA	NA
WP_014380299.1\|3069787_3070729_-	site-specific tyrosine recombinase XerD	A0A0K2CP59	Brevibacillus_phage	1.5e-19	25.2
WP_009955788.1\|3070725_3071349_-	NUDIX hydrolase	NA	NA	NA	NA
WP_014380300.1\|3071341_3073093_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.4e-127	45.6

DBSCAN-SWA_213

3081624 : 3085841

Pectobacterium_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955608.1\|3081624_3082887_-\|tRNA	tyrosine--tRNA ligase	A0A1L2CUL7	Pectobacterium_phage	5.9e-64	37.7
WP_014380308.1\|3082979_3083624_-	DNA-3-methyladenine glycosylase	NA	NA	NA	NA
WP_020188604.1\|3083720_3085001_+	ammonium transporter	H8ZJB2	Ostreococcus_tauri_virus	3.0e-39	31.2
WP_014380310.1\|3085076_3085841_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.0e-19	30.3

DBSCAN-SWA_214

3096890 : 3100627

Oenococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044059240.1\|3096890_3098009_+	mandelate racemase	Q6A202	Oenococcus_phage	2.1e-17	24.5
WP_029385522.1\|3098099_3098786_+	ANTAR domain-containing protein	NA	NA	NA	NA
WP_009957485.1\|3098809_3100627_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2I4R674	Erysipelothrix_phage	2.5e-39	26.6

DBSCAN-SWA_215

3106400 : 3119166

Paenibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380319.1\|3106400_3112796_-	type I polyketide synthase	D0R7J2	Paenibacillus_phage	1.3e-21	29.4
WP_014380320.1\|3112776_3119166_-	type I polyketide synthase	D0R7J2	Paenibacillus_phage	4.2e-25	30.7

DBSCAN-SWA_216

3124550 : 3125753

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380323.1\|3124550_3125753_-	acetylornithine transaminase	A0A249XSK4	Mycobacterium_phage	2.5e-16	27.0

DBSCAN-SWA_217

3131456 : 3132500

Orpheovirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380327.1\|3131456_3132500_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	5.1e-29	37.5

DBSCAN-SWA_218

3137194 : 3141614

Vibrio_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071357.1\|3137194_3137800_-	translation initiation factor IF-3	A0A2I7S9Q1	Vibrio_phage	1.6e-11	34.5
WP_080552541.1\|3138305_3141614_+\|tRNA	bifunctional lysylphosphatidylglycerol synthetase/lysine--tRNA ligase LysX	A0A1V0SIS0	Klosneuvirus	7.4e-74	34.8

DBSCAN-SWA_219

3147744 : 3149115

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954195.1\|3147744_3149115_+	cytochrome P450	S4VQU1	Pandoravirus	3.8e-16	23.0

DBSCAN-SWA_220

3153243 : 3156994

uncultured_Mediterranean_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380341.1\|3153243_3156162_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	7.0e-294	53.3
WP_020188595.1\|3156295_3156994_+	MBL fold metallo-hydrolase	A0A221J762	Mycobacterium_phage	9.9e-13	69.8

DBSCAN-SWA_221

3163336 : 3172237

Bodo_saltans_virus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380346.1\|3163336_3165376_-	serine/threonine protein kinase	A0A2H4UVE2	Bodo_saltans_virus	5.1e-17	28.2
WP_193375118.1\|3165530_3168128_+	FHA domain-containing protein	A0A2R8FG22	Brazilian_cedratvirus	3.0e-30	32.8
WP_009954966.1\|3168222_3168663_+	DUF402 domain-containing protein	NA	NA	NA	NA
WP_009954965.1\|3168674_3168836_-	hypothetical protein	NA	NA	NA	NA
WP_009954964.1\|3168923_3169565_+	chemotaxis protein CheB	NA	NA	NA	NA
WP_009954963.1\|3169570_3170569_+	non-homologous end-joining DNA ligase	G8GER3	unidentified_phage	6.2e-08	29.4
WP_009954961.1\|3170568_3171459_+	non-homologous end-joining DNA ligase	NA	NA	NA	NA
WP_014380349.1\|3171451_3172237_+	Fpg/Nei family DNA glycosylase	A0A1V0CNR6	Kaumoebavirus	1.5e-09	25.4

DBSCAN-SWA_222

3177685 : 3182987

Listeria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008257678.1\|3177685_3180346_-	DNA polymerase I	A0A060AFQ3	Listeria_phage	1.2e-42	30.6
WP_009954952.1\|3180510_3180993_+	Zn-ribbon domain-containing OB-fold protein	NA	NA	NA	NA
WP_008257683.1\|3180998_3182201_+	lipid-transfer protein	NA	NA	NA	NA
WP_008257686.1\|3182372_3182987_-	ANTAR domain-containing response regulator	Q6XM27	Feldmannia_irregularis_virus	3.9e-05	31.7

DBSCAN-SWA_223

3188590 : 3190204

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044059241.1\|3188590_3190204_+	thiol reductant ABC exporter subunit CydD	M1H3A1	Paramecium_bursaria_Chlorella_virus	4.6e-05	34.3

DBSCAN-SWA_224

3200558 : 3201377

Acinetobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008257758.1\|3200558_3201377_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	3.6e-30	36.9

DBSCAN-SWA_225

3209405 : 3210539

Faustovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008257769.1\|3209405_3210539_-	histidinol-phosphate transaminase	A0A1X7QHI1	Faustovirus	6.3e-17	29.6

DBSCAN-SWA_226

3231340 : 3236648

Klosneuvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380373.1\|3231340_3232645_-	adenosylmethionine--8-amino-7-oxononanoate transaminase	A0A1V0SKB7	Klosneuvirus	6.8e-15	27.8
WP_008257820.1\|3232707_3233145_+	hypothetical protein	NA	NA	NA	NA
WP_014380374.1\|3233478_3234360_+	NlpC/P60 family peptidoglycan-binding protein RipD	A0A1J0GW44	Streptomyces_phage	4.6e-07	34.9
WP_014380375.1\|3234461_3236648_+	acyltransferase	A0A166XZF2	Gordonia_phage	1.7e-55	28.9

DBSCAN-SWA_227

3251289 : 3258582

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380383.1\|3251289_3253116_-	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	1.3e-40	23.8
WP_009955512.1\|3253216_3254089_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_009955511.1\|3254067_3254457_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_008257855.1\|3254517_3254979_+	PPOX class F420-dependent oxidoreductase	NA	NA	NA	NA
WP_008257857.1\|3255048_3258582_-	DNA polymerase III subunit alpha	Q8W6C3	Saccharomonospora_phage	0.0e+00	60.4

DBSCAN-SWA_228

3266947 : 3316183

Tupanvirus(75.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380389.1\|3266947_3270061_-\|tRNA	isoleucine--tRNA ligase	A0A2P1ELB8	Moumouvirus	1.2e-163	35.0
WP_008257871.1\|3270267_3270513_-	hypothetical protein	NA	NA	NA	NA
WP_014380390.1\|3271065_3272190_-	nitronate monooxygenase	NA	NA	NA	NA
WP_009957085.1\|3272259_3272835_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_014380391.1\|3272955_3297729_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	3.0e-143	26.2
WP_009953336.1\|3298256_3305915_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	9.0e-99	20.8
WP_014380392.1\|3305911_3316183_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	2.1e-71	24.9

DBSCAN-SWA_229

3327237 : 3336131

Ostreococcus_tauri_virus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380400.1\|3327237_3327969_-	FkbM family methyltransferase	G8DGX3	Emiliania_huxleyi_virus	7.9e-05	28.7
WP_026071341.1\|3328054_3329017_-	GDP-L-fucose synthase	D1LW79	Prochlorococcus_phage	7.6e-88	50.3
WP_014380402.1\|3329024_3330047_-	GDP-mannose 4,6-dehydratase	M1IBC3	Acanthocystis_turfacea_Chlorella_virus	1.1e-105	56.9
WP_014380403.1\|3330305_3331196_-	hypothetical protein	H8ZJG6	Ostreococcus_tauri_virus	1.1e-19	32.2
WP_026071340.1\|3331407_3332181_+	glucose-1-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_014380405.1\|3332162_3333257_+	CDP-glucose 4,6-dehydratase	J7Q7J8	Aeropyrum_coil-shaped_virus	2.6e-15	28.1
WP_014380406.1\|3333253_3333805_+	dTDP-4-dehydrorhamnose 3,5-epimerase family protein	I7HJC4	Enterobacteria_phage	1.3e-23	39.2
WP_014380407.1\|3333822_3335025_+	methyltransferase domain-containing protein	A0A1V0SJ68	Klosneuvirus	4.0e-22	27.2
WP_014380408.1\|3335021_3336131_+	DegT/DnrJ/EryC1/StrS family aminotransferase	C7U074	Ostreococcus_tauri_virus	2.4e-21	26.9

DBSCAN-SWA_230

3340125 : 3351589

Shahe_endorna-like_virus(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380414.1\|3340125_3341160_+	GDP-mannose 4,6-dehydratase	Q58M98	Prochlorococcus_phage	1.5e-70	44.1
WP_014380415.1\|3341156_3342242_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_014380416.1\|3342500_3343757_+	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	2.5e-06	37.1
WP_014380417.1\|3343764_3344544_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_026071338.1\|3344640_3345432_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_009953300.1\|3345559_3346366_-	class I SAM-dependent methyltransferase	A0A2R8FDY2	Brazilian_cedratvirus	7.6e-57	53.1
WP_080587937.1\|3346461_3347748_-	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	3.6e-08	42.9
WP_009953297.1\|3348161_3349430_-	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	4.3e-06	38.7
WP_026071337.1\|3349522_3350329_-	class I SAM-dependent methyltransferase	A0A2R8FDY2	Brazilian_cedratvirus	9.2e-55	52.6
WP_014380421.1\|3350482_3351589_-	NAD-dependent epimerase/dehydratase family protein	M1I1Z9	Acanthocystis_turfacea_Chlorella_virus	1.6e-17	24.1

DBSCAN-SWA_231

3367221 : 3379089

Hepacivirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380432.1\|3367221_3377502_+	non-ribosomal peptide synthetase	Q75ZG1	Hepacivirus	4.1e-06	23.2
WP_014380433.1\|3377607_3379089_-	HAMP domain-containing histidine kinase	A0A2K9L0Z8	Tupanvirus	1.2e-07	28.7

DBSCAN-SWA_232

3385824 : 3386592

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953266.1\|3385824_3386592_-	beta-ketoacyl-ACP reductase	Q06VL0	Trichoplusia_ni_ascovirus	5.2e-07	25.1

DBSCAN-SWA_233

3390871 : 3393068

Gordonia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008257972.1\|3390871_3391606_-	NlpC/P60 family peptidoglycan endopeptidase RipB	A0A0K0NL58	Gordonia_phage	3.1e-17	42.7
WP_044059217.1\|3391631_3393068_-	NlpC/P60 family peptidoglycan endopeptidase RipA	Q9T1E7	Lactobacillus_phage	1.0e-11	33.8

DBSCAN-SWA_234

3397915 : 3400787

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380445.1\|3397915_3399553_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L0W2	Tupanvirus	1.1e-33	23.5
WP_008257990.1\|3399580_3400390_-	enoyl-CoA hydratase	NA	NA	NA	NA
WP_009953261.1\|3400433_3400787_-	thioredoxin	A0A2H4P7M6	Pseudomonas_phage	6.5e-13	33.7

DBSCAN-SWA_235

3409081 : 3411670

Mycobacterium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955750.1\|3409081_3409582_-	SUF system NifU family Fe-S cluster assembly protein	A0A0K1LSF9	Mycobacterium_phage	2.2e-22	45.5
WP_009955751.1\|3409578_3410895_-	cysteine desulfurase	Q2XUY6	environmental_halophage	1.4e-100	45.8
WP_009955752.1\|3410896_3411670_-	Fe-S cluster assembly ATPase SufC	W8CYL7	Bacillus_phage	2.1e-08	28.3

DBSCAN-SWA_236

3416933 : 3417869

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380451.1\|3416933_3417869_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.9e-17	30.3

DBSCAN-SWA_237

3426019 : 3431618

Cyanophage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955768.1\|3426019_3427564_+	glucose-6-phosphate dehydrogenase	M4SIY3	Cyanophage	1.0e-73	35.2
WP_008258116.1\|3427563_3428475_+	glucose-6-phosphate dehydrogenase assembly protein OpcA	NA	NA	NA	NA
WP_009955770.1\|3428471_3429227_+	6-phosphogluconolactonase	NA	NA	NA	NA
WP_009955772.1\|3429272_3429671_+	hypothetical protein	NA	NA	NA	NA
WP_014380459.1\|3429684_3430614_+	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	4.2e-43	35.0
WP_009951912.1\|3430628_3431618_-	aldo/keto reductase	A0A1V0SKP9	Klosneuvirus	6.5e-10	25.8

DBSCAN-SWA_238

3446448 : 3449339

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380468.1\|3446448_3448068_+	bile acid CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.3e-28	28.1
WP_014380469.1\|3448067_3449339_+	alpha/beta hydrolase	A0A068F2G2	Mycobacterium_phage	6.8e-36	38.5

DBSCAN-SWA_239

3453520 : 3455505

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956168.1\|3453520_3454597_-	YvcK family protein	A1IMD5	Streptococcus_phage	3.4e-36	36.2
WP_008258167.1\|3454593_3455505_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.7e-09	34.2

DBSCAN-SWA_240

3461392 : 3467326

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008258173.1\|3461392_3461875_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.8e-13	41.4
WP_008258174.1\|3461924_3463202_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	3.3e-91	45.6
WP_014380477.1\|3463325_3463925_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	6.9e-31	41.0
WP_008258177.1\|3464043_3464751_+	LppX_LprAFG lipoprotein	NA	NA	NA	NA
WP_008258179.1\|3464747_3466304_+	MFS transporter	NA	NA	NA	NA
WP_014380478.1\|3466300_3467326_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	8.2e-40	34.7

DBSCAN-SWA_241

3475085 : 3481909

Acanthamoeba_polyphaga_mimivirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955076.1\|3475085_3476051_+	alpha/beta hydrolase	A0A2L2DMU8	Acanthamoeba_polyphaga_mimivirus	8.5e-23	31.2
WP_036429282.1\|3476097_3477585_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_008258191.1\|3477605_3478172_+	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_008258192.1\|3478247_3479459_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	8.6e-113	54.7
WP_008258194.1\|3479553_3480816_-	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	2.2e-39	33.9
WP_008258195.1\|3480837_3481164_-	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_085981088.1\|3481237_3481909_-	guanylate kinase	K4JYM5	Abalone_herpesvirus	9.2e-16	34.2

DBSCAN-SWA_242

3487611 : 3491505

Halovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020415577.1\|3487611_3488748_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	6.5e-38	31.5
WP_014380487.1\|3488744_3489260_-	hypothetical protein	NA	NA	NA	NA
WP_009951742.1\|3489256_3490549_-	dihydroorotase	NA	NA	NA	NA
WP_009951741.1\|3490545_3491505_-	aspartate carbamoyltransferase catalytic subunit	M1I6M4	Paramecium_bursaria_Chlorella_virus	2.3e-28	36.7

DBSCAN-SWA_243

3497006 : 3497756

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008258209.1\|3497006_3497756_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.0e-27	33.3

DBSCAN-SWA_244

3509851 : 3511057

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008258240.1\|3509851_3511057_-	chorismate synthase	A0A291AU41	Pandoravirus	2.0e-45	36.1

DBSCAN-SWA_245

3515362 : 3521869

Tupanvirus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955913.1\|3515362_3518077_-\|tRNA	alanine--tRNA ligase	A0A2K9L1X7	Tupanvirus	1.2e-66	35.4
WP_008258256.1\|3518208_3518598_-	YjbQ family protein	NA	NA	NA	NA
WP_014382843.1\|3518762_3519383_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_008258260.1\|3519535_3520159_+	hypothetical protein	NA	NA	NA	NA
WP_009955916.1\|3520172_3520508_-	hypothetical protein	NA	NA	NA	NA
WP_038536736.1\|3520504_3521869_-	replication-associated recombination protein A	G3MBE0	Bacillus_virus	8.0e-83	43.6

DBSCAN-SWA_246

3533573 : 3536874

Rhodococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957661.1\|3533573_3534452_+	neutral zinc metallopeptidase	A0A1I9SA48	Rhodococcus_phage	1.2e-52	47.1
WP_009957662.1\|3534562_3535444_-	dihydrodipicolinate synthase family protein	NA	NA	NA	NA
WP_014380510.1\|3535480_3536278_-	aldolase	NA	NA	NA	NA
WP_008258289.1\|3536349_3536874_+	helix-turn-helix domain-containing protein	I3VYZ1	Thermoanaerobacterium_phage	5.7e-05	37.8

DBSCAN-SWA_247

3544884 : 3562538

Klosneuvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954372.1\|3544884_3545775_+	peptidylprolyl isomerase	A0A1V0SCU1	Indivirus	1.4e-08	34.8
WP_009954371.1\|3545787_3548166_-	RelA/SpoT family protein	NA	NA	NA	NA
WP_029384615.1\|3548301_3548844_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	3.8e-12	33.6
WP_085977604.1\|3548851_3550486_-	hypothetical protein	NA	NA	NA	NA
WP_009955490.1\|3550548_3551847_-	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	8.2e-21	30.0
WP_014380515.1\|3551851_3553678_-	protein translocase subunit SecD	NA	NA	NA	NA
WP_008258310.1\|3553790_3554117_-	preprotein translocase subunit YajC	NA	NA	NA	NA
WP_009953660.1\|3554328_3555669_+	4-aminobutyrate--2-oxoglutarate transaminase	A0A1V0SKB7	Klosneuvirus	1.4e-23	25.8
WP_014380518.1\|3555807_3559332_+	carboxylic acid reductase	A0A1V0SBX8	Catovirus	8.8e-17	22.5
WP_009953663.1\|3559395_3560088_-	hypothetical protein	NA	NA	NA	NA
WP_008258316.1\|3560217_3560604_-	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_020188556.1\|3560702_3561389_-	hypothetical protein	NA	NA	NA	NA
WP_009956162.1\|3561482_3562538_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	1.6e-06	23.9

DBSCAN-SWA_248

3565928 : 3567506

Heterosigma_akashiwo_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955060.1\|3565928_3567506_+	polyamine aminopropyltransferase	A0A1C9C533	Heterosigma_akashiwo_virus	3.3e-08	32.2

DBSCAN-SWA_249

3575376 : 3579299

Tupanvirus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953630.1\|3575376_3577452_-\|tRNA	threonine--tRNA ligase	A0A2K9L6B6	Tupanvirus	2.1e-103	36.0
WP_193375155.1\|3577550_3579299_+	cation:proton antiporter	A0A2H4J178	uncultured_Caudovirales_phage	2.4e-07	25.2

DBSCAN-SWA_250

3603081 : 3604629

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380551.1\|3603081_3604629_+	long-chain-fatty-acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.2e-29	26.2

DBSCAN-SWA_251

3609476 : 3616908

Mycobacterium_phage(40.0%)

integrase,terminase,head,protease,capsid

attL 3607735:3607762|attR 3617092:3617119

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3607735:3607762	attL	NA	NA	NA	NA
WP_041787084.1\|3609476_3609950_-\|terminase	phage terminase small subunit P27 family	V9H0V4	Actinophage	2.0e-17	52.7
WP_014380560.1\|3610044_3611475_-\|capsid	phage major capsid protein	A0A1B3AZZ4	Gordonia_phage	3.2e-74	47.1
WP_080587941.1\|3611478_3612099_-\|head,protease	HK97 family phage prohead protease	G9FGV2	Rhodococcus_phage	8.0e-06	32.6
WP_041787085.1\|3612148_3612664_-	hypothetical protein	NA	NA	NA	NA
WP_158520010.1\|3613299_3614649_-	AAA family ATPase	NA	NA	NA	NA
WP_014380567.1\|3615043_3615265_-	excisionase family DNA-binding protein	A0A2P1CHK7	Mycobacterium_phage	2.5e-18	77.2
WP_148278277.1\|3615353_3615746_-	hypothetical protein	NA	NA	NA	NA
WP_014380569.1\|3615747_3616908_-\|integrase	tyrosine-type recombinase/integrase	A0A1D8EV90	Mycobacterium_phage	1.6e-60	38.7
3617092:3617119	attR	NA	NA	NA	NA

DBSCAN-SWA_252

3635900 : 3636671

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952068.1\|3635900_3636671_+	hypothetical protein	B5LJM1	Mycobacterium_phage	3.7e-13	40.5

DBSCAN-SWA_253

3661256 : 3661721

Streptomyces_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008258542.1\|3661256_3661721_-	dUTP diphosphatase	A0A2L1IVN2	Streptomyces_phage	2.0e-30	49.7

DBSCAN-SWA_254

3665373 : 3671005

Cyanophage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071295.1\|3665373_3666879_+	RNA polymerase sigma factor	M4SMP8	Cyanophage	2.6e-42	34.6
WP_009955738.1\|3667014_3667431_+	RidA family protein	NA	NA	NA	NA
WP_009955739.1\|3667376_3667748_-	DUF952 domain-containing protein	NA	NA	NA	NA
WP_008258551.1\|3667871_3668057_+	hypothetical protein	NA	NA	NA	NA
WP_009955740.1\|3668121_3669123_+	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
WP_008258553.1\|3669123_3669363_-	DUF3039 domain-containing protein	A0A059VGG3	Mycobacterium_phage	1.3e-12	46.1
WP_008258554.1\|3669433_3669880_+	DUF3099 domain-containing protein	NA	NA	NA	NA
WP_050782802.1\|3670015_3671005_+	sigma-70 family RNA polymerase sigma factor SigB	M4SMP8	Cyanophage	5.1e-39	36.9

DBSCAN-SWA_255

3674129 : 3682153

Erysipelothrix_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954997.1\|3674129_3675545_+	Si-specific NAD(P)(+) transhydrogenase	A0A2K5B2C5	Erysipelothrix_phage	5.4e-42	27.6
WP_014380596.1\|3675632_3676469_-	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_008258561.1\|3676699_3677671_+	PAC2 family protein	NA	NA	NA	NA
WP_009955001.1\|3677731_3678763_+	alpha/beta hydrolase	G1DAB1	Mycobacterium_virus	3.4e-17	29.5
WP_014380598.1\|3678808_3679495_+	PhzF family phenazine biosynthesis protein	NA	NA	NA	NA
WP_009955003.1\|3679519_3680005_-	FABP family protein	NA	NA	NA	NA
WP_008258565.1\|3680039_3680504_-	transcriptional repressor NrdR	NA	NA	NA	NA
WP_008258566.1\|3680656_3681151_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_008258568.1\|3681442_3682153_+	repressor LexA	A0A1B1P7Q3	Bacillus_phage	8.0e-10	49.2

DBSCAN-SWA_256

3695435 : 3696488

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008258595.1\|3695435_3696488_-	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	2.7e-131	73.7

DBSCAN-SWA_257

3704115 : 3706620

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_193375120.1\|3704115_3706620_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	1.8e-112	58.6

DBSCAN-SWA_258

3711580 : 3715832

Gordonia_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955239.1\|3711580_3712333_-	FAD-dependent thymidylate synthase	A0A166Y9A6	Gordonia_phage	7.1e-49	54.4
WP_014380623.1\|3712382_3713594_-	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_009955236.1\|3713646_3714381_-	cell division protein DivIVA	NA	NA	NA	NA
WP_008258621.1\|3714480_3714966_-	dihydrofolate reductase	A0A1L7N103	Ralstonia_phage	1.1e-18	39.3
WP_014380625.1\|3715031_3715832_-	thymidylate synthase	A0A1B3AY68	Gordonia_phage	6.0e-107	68.2

DBSCAN-SWA_259

3739137 : 3740457

Acanthamoeba_polyphaga_lentillevirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071285.1\|3739137_3740457_-	insulinase family protein	J3IZ03	Acanthamoeba_polyphaga_lentillevirus	7.1e-28	24.1

DBSCAN-SWA_260

3758825 : 3761597

Bodo_saltans_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041787088.1\|3758825_3761597_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	3.2e-22	23.8

DBSCAN-SWA_261

3766876 : 3768484

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071284.1\|3766876_3768484_-	MFS transporter	A0A0M3UL24	Mycobacterium_phage	1.2e-42	33.3

DBSCAN-SWA_262

3776747 : 3778127

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008258759.1\|3776747_3778127_+	mycothione reductase	A0A2K5B2C5	Erysipelothrix_phage	1.3e-32	25.4

DBSCAN-SWA_263

3783030 : 3786815

Mycobacterium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380671.1\|3783030_3783990_+	PPE family protein	V5UPR1	Mycobacterium_phage	7.0e-09	32.2
WP_014380672.1\|3783961_3784741_-	3-oxoacyl-ACP reductase	A0A0M4JSW6	Mollivirus	5.1e-10	26.3
WP_014380673.1\|3784744_3786109_-	aldehyde dehydrogenase	NA	NA	NA	NA
WP_014380674.1\|3786110_3786815_-	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	A0A2P9FI75	Pseudomonas_phage	8.7e-09	47.0

DBSCAN-SWA_264

3807587 : 3808427

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952689.1\|3807587_3808427_+	SDR family oxidoreductase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	4.0e-61	46.8

DBSCAN-SWA_265

3812387 : 3813566

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952697.1\|3812387_3813566_-	phosphatidylserine decarboxylase	A0A2K9L169	Tupanvirus	2.5e-32	29.8

DBSCAN-SWA_266

3818819 : 3819716

Brevibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380689.1\|3818819_3819716_-	tyrosine recombinase XerC	A0A0K2CP59	Brevibacillus_phage	1.8e-19	26.7

DBSCAN-SWA_267

3830547 : 3831267

Phaeocystis_globosa_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955194.1\|3830547_3831267_-	ribonuclease HII	R4THQ2	Phaeocystis_globosa_virus	7.6e-08	28.4

DBSCAN-SWA_268

3836648 : 3837536

Erythrobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955186.1\|3836648_3837536_+	D-alanyl-D-alanine carboxypeptidase	A0A1P8VVG5	Erythrobacter_phage	5.3e-11	35.1

DBSCAN-SWA_269

3843843 : 3845607

Saccharomonospora_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380702.1\|3843843_3845607_+	DEAD/DEAH box helicase	I4AZM6	Saccharomonospora_phage	3.1e-87	37.7

DBSCAN-SWA_270

3852030 : 3853362

uncultured_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380706.1\|3852030_3853362_-	signal recognition particle-docking protein FtsY	D6PHS7	uncultured_phage	4.5e-14	37.1

DBSCAN-SWA_271

3858781 : 3860342

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380710.1\|3858781_3859630_-	DNA-formamidopyrimidine glycosylase	F8WPX6	Bacillus_phage	3.6e-17	25.6
WP_009956337.1\|3859634_3860342_-	ribonuclease III	A0A2K9R4Y7	Dishui_lake_phycodnavirus	8.2e-23	36.8

DBSCAN-SWA_272

3865287 : 3870323

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953984.1\|3865287_3865770_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	1.6e-17	31.2
WP_014380717.1\|3865945_3866500_-	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_009955167.1\|3866510_3867143_-	vitamin K epoxide reductase family protein	NA	NA	NA	NA
WP_009955166.1\|3867139_3867907_-	DsbA family protein	NA	NA	NA	NA
WP_009955165.1\|3868002_3869121_-	alpha/beta hydrolase	M1PGN2	Moumouvirus	1.3e-30	34.6
WP_161807802.1\|3869477_3870323_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.2e-52	42.2

DBSCAN-SWA_273

3882864 : 3883548

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380726.1\|3882864_3883548_-	uracil-DNA glycosylase	S4VZ65	Pandoravirus	1.2e-34	39.6

DBSCAN-SWA_274

3891682 : 3892330

Streptomyces_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008259006.1\|3891682_3892330_-	HU family DNA-binding protein	A0A2P1N0A2	Streptomyces_phage	6.3e-14	45.4

DBSCAN-SWA_275

3902473 : 3904060

Brazilian_cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952790.1\|3902473_3904060_-	phosphoglycerate dehydrogenase	A0A2R8FDS8	Brazilian_cedratvirus	1.4e-38	36.8

DBSCAN-SWA_276

3907746 : 3909615

Ostreococcus_lucimarinus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008259036.1\|3907746_3909615_-	acetolactate synthase large subunit	A0A0P0CDR3	Ostreococcus_lucimarinus_virus	1.3e-54	27.3

DBSCAN-SWA_277

3915465 : 3916497

Micromonas_sp._RCC1109_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008259042.1\|3915465_3916497_-	6-phosphofructokinase	E5EQL4	Micromonas_sp._RCC1109_virus	6.6e-13	24.8

DBSCAN-SWA_278

3927664 : 3929746

Ralstonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954354.1\|3927664_3929746_-	NAD-dependent DNA ligase LigA	A0A0A8J9A9	Ralstonia_phage	2.4e-99	36.4

DBSCAN-SWA_279

3933518 : 3934697

Faustovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954359.1\|3933518_3934697_-	cysteine desulfurase	A0A1X7QGF3	Faustovirus	2.4e-27	25.5

DBSCAN-SWA_280

3962425 : 3963754

Bodo_saltans_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380764.1\|3962425_3963754_+	deoxyribodipyrimidine photo-lyase	A0A2H4UV63	Bodo_saltans_virus	4.4e-54	29.4

DBSCAN-SWA_281

3971479 : 3972340

Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071262.1\|3971479_3972340_-	ABC transporter ATP-binding protein	Q66093	Chlorella_virus	1.7e-06	26.0

DBSCAN-SWA_282

3976876 : 3979390

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008259160.1\|3976876_3977917_+	NAD(P)-dependent alcohol dehydrogenase	A0A2K9L7I1	Tupanvirus	1.6e-75	43.1
WP_008259162.1\|3977921_3978272_-	DUF3349 domain-containing protein	NA	NA	NA	NA
WP_009954743.1\|3978415_3979390_-	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	7.8e-157	85.3

DBSCAN-SWA_283

3983810 : 3990386

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380779.1\|3983810_3985928_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	V9VI16	Lactococcus_phage	6.5e-209	51.7
WP_008259183.1\|3985945_3986398_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A142F1R4	Bacillus_phage	5.8e-14	40.2
WP_008259184.1\|3986429_3986669_-	redoxin NrdH	V5UN81	Mycobacterium_phage	1.3e-20	63.2
WP_008259185.1\|3987197_3987752_-	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	1.2e-05	34.4
WP_009954736.1\|3987843_3988458_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_009954734.1\|3988466_3989510_+	DNA polymerase IV	F1C5A5	Cronobacter_phage	5.1e-21	29.1
WP_009954732.1\|3989444_3990386_-	SDR family oxidoreductase	W8CYX9	Bacillus_phage	7.1e-06	28.8

DBSCAN-SWA_284

4003224 : 4004751

Organic_Lake_phycodnavirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380787.1\|4003224_4004751_+	Hsp70 family protein	F2Y2E1	Organic_Lake_phycodnavirus	8.8e-22	26.0

DBSCAN-SWA_285

4020844 : 4021672

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380805.1\|4020844_4021672_+	mycofactocin-coupled SDR family oxidoreductase	W8CYX9	Bacillus_phage	2.3e-08	45.0

DBSCAN-SWA_286

4024706 : 4026565

Diadromus_pulchellus_ascovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954697.1\|4024706_4025450_-	SDR family oxidoreductase	F2NZ40	Diadromus_pulchellus_ascovirus	1.1e-17	32.2
WP_009954696.1\|4025470_4026565_-	ferredoxin--NADP reductase	A0A1D7SNA5	Cyanophage	1.2e-09	41.6

DBSCAN-SWA_287

4034672 : 4035050

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954685.1\|4034672_4035050_-	Fic family protein	A0A1B3AYM0	Gordonia_phage	6.9e-21	49.2

DBSCAN-SWA_288

4044150 : 4045614

Microcystis_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380817.1\|4044150_4045614_+	YdiU family protein	A0A075BSJ0	Microcystis_phage	6.2e-49	38.4

DBSCAN-SWA_289

4055906 : 4057427

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041787095.1\|4055906_4057427_-	adenylate/guanylate cyclase domain-containing protein	A0A1B1IWY2	uncultured_Mediterranean_phage	8.2e-20	34.4

DBSCAN-SWA_290

4061866 : 4077743

Mycobacterium_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_036389977.1\|4061866_4064404_+	ATP-binding cassette domain-containing protein	A0A2R8FG22	Brazilian_cedratvirus	1.8e-27	36.6
WP_014380837.1\|4064411_4067537_-	serine/threonine-protein kinase	M1IKX4	Paramecium_bursaria_Chlorella_virus	4.2e-10	28.4
WP_014380838.1\|4067634_4069836_-	acyltransferase	A0A166XZF2	Gordonia_phage	8.4e-74	32.2
WP_009954255.1\|4070052_4070493_+	nitroreductase family deazaflavin-dependent oxidoreductase	NA	NA	NA	NA
WP_014380839.1\|4070616_4071078_+	DUF1942 domain-containing protein	NA	NA	NA	NA
WP_080552517.1\|4071782_4071974_+	DUF3263 domain-containing protein	A0A0A7RXU7	Mycobacterium_phage	1.1e-06	42.1
WP_029384585.1\|4071970_4072684_+	DUF4352 domain-containing protein	A0A088F7R2	Mycobacterium_phage	4.5e-05	76.9
WP_009954259.1\|4072855_4073314_+	hypothetical protein	NA	NA	NA	NA
WP_014380840.1\|4073943_4074789_-	maleylpyruvate isomerase family mycothiol-dependent enzyme	NA	NA	NA	NA
WP_148278279.1\|4074808_4075651_-	DMT family transporter	NA	NA	NA	NA
WP_009954261.1\|4075647_4076157_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	2.0e-31	47.8
WP_009954262.1\|4076159_4077053_-	ABC transporter permease	NA	NA	NA	NA
WP_020415574.1\|4077053_4077743_-	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	6.1e-31	37.7

DBSCAN-SWA_291

4086031 : 4086829

Niemeyer_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954275.1\|4086031_4086829_+	slipin family protein	A0A0U2UF06	Niemeyer_virus	3.7e-24	29.2

DBSCAN-SWA_292

4131057 : 4132023

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380859.1\|4131057_4132023_-	alpha/beta hydrolase	A0A1C9LZ53	Mycobacterium_phage	4.7e-05	32.7

DBSCAN-SWA_293

4135702 : 4137805

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957455.1\|4135702_4137805_+	catalase	A0A2K9L572	Tupanvirus	2.5e-144	49.4

DBSCAN-SWA_294

4151534 : 4152194

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956825.1\|4151534_4152194_-	UdgX family uracil-DNA binding protein	S5M8J1	Bacillus_phage	6.0e-12	36.5

DBSCAN-SWA_295

4156009 : 4157803

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380872.1\|4156009_4157803_-	sensor domain-containing diguanylate cyclase	A0A127AWB9	Bacillus_phage	1.1e-10	33.6

DBSCAN-SWA_296

4181096 : 4184345

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380890.1\|4181096_4184345_-	thioester reductase domain-containing protein	A0A1V0SBX8	Catovirus	4.0e-08	25.2

DBSCAN-SWA_297

4202134 : 4203688

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956604.1\|4202134_4203688_+	GMC family oxidoreductase N-terminal domain-containing protein	A0A1V0S9M4	Catovirus	2.3e-49	30.2

DBSCAN-SWA_298

4219095 : 4227696

Propionibacterium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008259632.1\|4219095_4219347_-	WhiB family transcriptional regulator	A0A173G9I6	Propionibacterium_phage	2.7e-05	50.9
WP_009955799.1\|4219751_4221851_-	ATP-dependent DNA helicase UvrD2	A0A2H4UW05	Bodo_saltans_virus	5.6e-11	22.7
WP_036459570.1\|4222032_4222287_+	mycoredoxin Mrx1	NA	NA	NA	NA
WP_008259652.1\|4222297_4223230_-	NAD(+) diphosphatase	NA	NA	NA	NA
WP_008259653.1\|4223229_4224300_-	potassium channel family protein	NA	NA	NA	NA
WP_014380915.1\|4224348_4227696_-	ATP-dependent helicase	A7KV33	Bacillus_phage	3.0e-06	20.5

DBSCAN-SWA_299

4238632 : 4242438

Diachasmimorpha_longicaudata_entomopoxvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380922.1\|4238632_4240162_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	5.5e-48	32.3
WP_014380923.1\|4240178_4241405_+	lipase chaperone	NA	NA	NA	NA
WP_009956179.1\|4241637_4242438_-	ParA family protein	Q8JL10	Natrialba_phage	1.1e-15	32.4

DBSCAN-SWA_300

4246485 : 4249879

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003874607.1\|4246485_4246740_+	transcriptional regulator WhiB1	A0A2P1N2X5	Mycobacterium_phage	1.5e-11	43.9
WP_009952806.1\|4246800_4248300_-	sensor histidine kinase	NA	NA	NA	NA
WP_007773063.1\|4248350_4248566_-	biotin/lipoyl-binding carrier protein	NA	NA	NA	NA
WP_008259700.1\|4248905_4249220_-	mycothiol system anti-sigma-R factor	NA	NA	NA	NA
WP_008259701.1\|4249216_4249879_-	sigma-70 family RNA polymerase sigma factor	A0A076YQ50	Rhizobium_phage	3.1e-08	26.5

DBSCAN-SWA_301

4254275 : 4255025

Acanthamoeba_polyphaga_mimivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380935.1\|4254275_4255025_-	SDR family oxidoreductase	A0A0G2Y924	Acanthamoeba_polyphaga_mimivirus	2.5e-06	34.3

DBSCAN-SWA_302

4283837 : 4286799

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007168097.1\|4283837_4284524_-	two-component system response regulator MtrA	W8CYM9	Bacillus_phage	1.6e-39	37.6
WP_014380959.1\|4284604_4285237_-	dTMP kinase	NA	NA	NA	NA
WP_008259773.1\|4285326_4286799_-	adenosylhomocysteinase	S4VPF6	Pandoravirus	2.0e-39	28.2

DBSCAN-SWA_303

4297278 : 4297551

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008259804.1\|4297278_4297551_-	WhiB family transcriptional regulator	A0A2P1CGA4	Mycobacterium_phage	1.9e-28	77.5

DBSCAN-SWA_304

4302580 : 4318557

Enterobacteria_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008259820.1\|4302580_4303657_-	NDP-sugar synthase	I7I009	Enterobacteria_phage	1.3e-16	26.5
WP_008259824.1\|4303658_4304549_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_014385682.1\|4304541_4305429_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	1.2e-26	35.7
WP_041787102.1\|4305554_4307027_+	LCP family protein	NA	NA	NA	NA
WP_041787217.1\|4307075_4307750_+	TIGR03089 family protein	NA	NA	NA	NA
WP_008259830.1\|4307857_4308139_+	DUF1490 family protein	NA	NA	NA	NA
WP_014380975.1\|4308147_4310364_+	manganese-exporting P-type ATPase CtpC	E4ZFI9	Streptococcus_phage	5.1e-79	32.5
WP_014380976.1\|4310370_4311021_-	cation transporter	NA	NA	NA	NA
WP_009953221.1\|4311179_4312094_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_009953222.1\|4312109_4313306_+	CoA transferase	NA	NA	NA	NA
WP_009953223.1\|4313309_4315295_-	protein kinase	A0A2R8FG94	Cedratvirus	2.2e-09	27.5
WP_041787103.1\|4315310_4316417_-	phosphate ABC transporter substrate-binding protein PstS	NA	NA	NA	NA
WP_009953225.1\|4316601_4317396_+	ATP-binding cassette domain-containing protein	A0A1V0SE00	Indivirus	3.0e-13	26.1
WP_014380979.1\|4317432_4318557_+	phosphate ABC transporter substrate-binding protein PstS	A0A1D7SRJ6	Cyanophage	6.5e-14	25.9

DBSCAN-SWA_305

4322101 : 4326867

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953232.1\|4322101_4323703_-	CHASE3 domain-containing protein	W8CYF6	Bacillus_phage	6.0e-13	25.1
WP_014380982.1\|4323699_4324845_-	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_009953234.1\|4325092_4326262_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_162130892.1\|4326345_4326867_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	5.1e-22	47.8

DBSCAN-SWA_306

4341924 : 4345832

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008259929.1\|4341924_4342713_-	RNA polymerase sigma factor SigF	A0A218KDJ1	Bacillus_phage	4.5e-14	26.5
WP_008259930.1\|4342709_4343147_-	anti-sigma factor	NA	NA	NA	NA
WP_008259932.1\|4343578_4343890_-	hypothetical protein	NA	NA	NA	NA
WP_014380994.1\|4343944_4344328_-	hypothetical protein	NA	NA	NA	NA
WP_041787223.1\|4344479_4345832_-	L-lysine 6-transaminase	A0A1V0SKB7	Klosneuvirus	2.4e-111	44.9

DBSCAN-SWA_307

4359328 : 4360459

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381004.1\|4359328_4360459_-	PPE family protein	V5UPR1	Mycobacterium_phage	4.8e-09	30.3

DBSCAN-SWA_308

4371592 : 4373176

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381014.1\|4371592_4373176_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	3.0e-57	33.3

DBSCAN-SWA_309

4381786 : 4383073

Geobacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085977598.1\|4381786_4383073_-	thymidine phosphorylase	A0A0H3UZD4	Geobacillus_virus	2.1e-77	44.1

DBSCAN-SWA_310

4391392 : 4392634

Erythrobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381024.1\|4391392_4392634_+	D-alanyl-D-alanine carboxypeptidase	A0A1P8VVG5	Erythrobacter_phage	2.4e-09	30.7

DBSCAN-SWA_311

4402564 : 4403953

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954112.1\|4402564_4403953_+	bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase	A0A0B5JD48	Pandoravirus	7.2e-15	26.5

DBSCAN-SWA_312

4410936 : 4415988

Brazilian_cedratvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041787225.1\|4410936_4413600_+	ATP-binding cassette domain-containing protein	A0A2R8FG22	Brazilian_cedratvirus	9.3e-27	35.7
WP_014381032.1\|4413636_4415988_+	ATP-binding cassette domain-containing protein	A0A2R8FFL6	Cedratvirus	1.4e-26	33.9

DBSCAN-SWA_313

4423209 : 4427842

Staphylococcus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_179293485.1\|4423209_4424328_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	3.9e-35	32.8
WP_014381035.1\|4424554_4427842_-	error-prone DNA polymerase	R4TMT6	Streptomyces_phage	1.4e-117	32.1

DBSCAN-SWA_314

4432783 : 4433671

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381039.1\|4432783_4433671_-	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	1.6e-31	32.3

DBSCAN-SWA_315

4440703 : 4442314

Hokovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_193375125.1\|4440703_4442314_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.1e-11	26.1

DBSCAN-SWA_316

4452090 : 4453686

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954981.1\|4452090_4453686_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	9.0e-86	38.6

DBSCAN-SWA_317

4456778 : 4457081

Mycobacterium_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952496.1\|4456778_4457081_+	WhiB family transcriptional regulator	I6XD27	Mycobacterium_virus	1.2e-10	44.2

DBSCAN-SWA_318

4463057 : 4466338

uncultured_virus(66.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957477.1\|4463057_4464674_-	chaperonin GroEL	A0A219YK78	uncultured_virus	8.7e-137	50.9
WP_007167930.1\|4464769_4465072_-	co-chaperone GroES	A0A221S3C8	uncultured_virus	5.6e-21	54.8
WP_014381060.1\|4465312_4466338_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A291ATS8	Pandoravirus	1.2e-35	37.0

DBSCAN-SWA_319

4474951 : 4476817

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952459.1\|4474951_4476817_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	M1H1Z3	Paramecium_bursaria_Chlorella_virus	9.8e-100	37.1

DBSCAN-SWA_320

4486185 : 4494029

Mycobacterium_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381072.1\|4486185_4489875_-	type VII secretion protein EccCb	V5UPA0	Mycobacterium_phage	3.8e-79	28.0
WP_014381073.1\|4489968_4491378_+	type VII secretion integral membrane protein EccD	NA	NA	NA	NA
WP_044059247.1\|4491422_4492691_+\|protease	type VII secretion-associated serine protease mycosin	V5UPA7	Mycobacterium_phage	2.2e-47	34.9
WP_014381075.1\|4492655_4494029_-	type VII secretion protein EccB	V5UN45	Mycobacterium_phage	1.5e-28	29.7

DBSCAN-SWA_321

4500649 : 4510993

Burkholderia_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381081.1\|4500649_4502314_+	FAD-dependent oxidoreductase	G3MA85	Bacillus_virus	1.1e-33	29.9
WP_014381082.1\|4502310_4503837_+	cyclic nucleotide-binding domain-containing protein	W8CYF6	Bacillus_phage	4.4e-13	38.2
WP_014381083.1\|4503876_4504725_+	LLM class F420-dependent oxidoreductase	NA	NA	NA	NA
WP_014381084.1\|4504745_4505612_+	LLM class F420-dependent oxidoreductase	NA	NA	NA	NA
WP_014381085.1\|4505639_4506635_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	2.2e-74	46.2
WP_036459800.1\|4506636_4507254_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.3e-27	38.8
WP_014381087.1\|4507453_4508575_+	acyltransferase	A9YX16	Burkholderia_phage	1.3e-14	27.7
WP_009952895.1\|4508704_4509841_+	acyltransferase	A9YX16	Burkholderia_phage	2.2e-17	27.5
WP_014381088.1\|4509904_4510993_+	acyltransferase	A9YX16	Burkholderia_phage	7.9e-17	29.7

DBSCAN-SWA_322

4519686 : 4520742

Faustovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956590.1\|4519686_4520742_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	A0A1X7QHI1	Faustovirus	5.3e-10	28.8

DBSCAN-SWA_323

4524226 : 4524922

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956588.1\|4524226_4524922_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.0e-31	38.5

DBSCAN-SWA_324

4532109 : 4532655

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956578.1\|4532109_4532655_-	adenylate kinase	A0A2K9L833	Tupanvirus	1.8e-14	33.8

DBSCAN-SWA_325

4537236 : 4538217

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041785209.1\|4537236_4538217_+	3-phosphoglycerate dehydrogenase	M1HBE3	Paramecium_bursaria_Chlorella_virus	3.8e-18	28.3

DBSCAN-SWA_326

4553522 : 4554413

Microcystis_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381115.1\|4553522_4554413_-	formylglycine-generating enzyme family protein	A0A075BSL8	Microcystis_phage	4.3e-21	31.4

DBSCAN-SWA_327

4564824 : 4566270

Acanthamoeba_castellanii_mimivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014385804.1\|4564824_4566270_-	mycofactocin system GMC family oxidoreductase MftG	A0A1E1EUP9	Acanthamoeba_castellanii_mimivirus	4.3e-10	21.9

DBSCAN-SWA_328

4573200 : 4574061

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381127.1\|4573200_4574061_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	7.3e-50	41.7

DBSCAN-SWA_329

4579439 : 4582846

Hokovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008260847.1\|4579439_4580630_-	elongation factor Tu	A0A1V0SGC3	Hokovirus	1.4e-30	27.4
WP_008260848.1\|4580740_4582846_-	elongation factor G	E4ZFJ7	Streptococcus_phage	2.7e-61	26.5

DBSCAN-SWA_330

4591656 : 4600588

Vibrio_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381138.1\|4591656_4595607_-	DNA-directed RNA polymerase subunit beta'	A0A2I7QNZ7	Vibrio_phage	1.2e-51	26.8
WP_085977595.1\|4595651_4599170_-	DNA-directed RNA polymerase subunit beta	A0A1B1ISA9	uncultured_Mediterranean_phage	3.7e-39	22.5
WP_008260873.1\|4599577_4600588_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.4e-23	35.1

DBSCAN-SWA_331

4611865 : 4616128

Micromonas_pusilla_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020823622.1\|4611865_4613212_+	AarF/ABC1/UbiB kinase family protein	G8DDN0	Micromonas_pusilla_virus	1.1e-31	29.4
WP_008260899.1\|4613214_4614120_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_008260900.1\|4614208_4615069_+	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	3.4e-23	28.4
WP_008260901.1\|4615231_4616128_+	class I SAM-dependent methyltransferase	A0A2I2L5L3	Orpheovirus	1.2e-23	29.2

DBSCAN-SWA_332

4628878 : 4631686

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381154.1\|4628878_4629883_-	patatin-like phospholipase family protein	A0A2K9KZN5	Tupanvirus	4.0e-07	24.1
WP_009957399.1\|4629883_4630351_-	cyanase	NA	NA	NA	NA
WP_014381155.1\|4630372_4631122_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_009957403.1\|4631170_4631686_-	nitroreductase family protein	A0A1V0E011	Clostridioides_phage	3.4e-10	27.0

DBSCAN-SWA_333

4636052 : 4641073

Cafeteria_roenbergensis_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381158.1\|4636052_4639355_+	exodeoxyribonuclease V subunit beta	E3T5J8	Cafeteria_roenbergensis_virus	1.0e-06	19.6
WP_014381159.1\|4639351_4641073_+	exodeoxyribonuclease V subunit alpha	A0A0K2FLP8	Brevibacillus_phage	4.0e-15	24.2

DBSCAN-SWA_334

4659183 : 4660056

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381173.1\|4659183_4660056_-	alpha/beta fold hydrolase	G1DB77	Mycobacterium_phage	7.7e-15	29.3

DBSCAN-SWA_335

4690922 : 4692524

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009951867.1\|4690922_4692524_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	3.3e-27	25.7

DBSCAN-SWA_336

4701539 : 4702658

Staphylococcus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_179293485.1\|4701539_4702658_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	3.9e-35	32.8

DBSCAN-SWA_337

4707993 : 4709022

Bodo_saltans_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381202.1\|4707993_4709022_-	NAD-dependent epimerase/dehydratase family protein	A0A2H4UUK0	Bodo_saltans_virus	8.0e-19	26.9

DBSCAN-SWA_338

4722832 : 4726399

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381207.1\|4722832_4726399_+	thioester reductase domain-containing protein	A0A1V0SBX8	Catovirus	8.6e-12	24.5

DBSCAN-SWA_339

4731622 : 4735953

Gordonia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381213.1\|4731622_4733746_+	acyltransferase	A0A166XZF2	Gordonia_phage	4.0e-73	32.2
WP_026071180.1\|4733937_4734624_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_014381214.1\|4734714_4735953_-	acyltransferase	A0A2H4JA46	uncultured_Caudovirales_phage	1.4e-14	26.7

DBSCAN-SWA_340

4749093 : 4750020

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261174.1\|4749093_4750020_+	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	4.3e-24	30.1

DBSCAN-SWA_341

4758625 : 4760576

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261205.1\|4758625_4759309_-	two-component sensory transduction protein RegX	W8CYM9	Bacillus_phage	3.4e-42	40.4
WP_008261206.1\|4759346_4760576_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	1.9e-27	33.0

DBSCAN-SWA_342

4775921 : 4777709

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_036459758.1\|4775921_4776788_+	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	4.5e-31	32.4
WP_009953526.1\|4776848_4777709_-	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	6.9e-32	33.5

DBSCAN-SWA_343

4783744 : 4785142

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953525.1\|4783744_4785142_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	3.6e-46	28.4

DBSCAN-SWA_344

4788279 : 4794094

Klosneuvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_036459815.1\|4788279_4790460_+	S9 family peptidase	A0A1V0SHT0	Klosneuvirus	1.5e-30	30.8
WP_009953520.1\|4790470_4790782_+	hypothetical protein	NA	NA	NA	NA
WP_008261283.1\|4790789_4791701_+	crotonase/enoyl-CoA hydratase family protein	NA	NA	NA	NA
WP_008261284.1\|4791780_4792233_+	DUF5078 domain-containing protein	NA	NA	NA	NA
WP_009953519.1\|4792481_4793129_+	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.9e-34	41.1
WP_009953517.1\|4793125_4794094_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A0N7CCA3	Skermania_phage	4.3e-131	72.7

DBSCAN-SWA_345

4806674 : 4808300

uncultured_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261313.1\|4806674_4808300_-	chaperonin GroEL	A0A240F779	uncultured_virus	6.0e-154	55.7

DBSCAN-SWA_346

4816610 : 4818782

Phaeocystis_globosa_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071168.1\|4816610_4818782_+	AAA family ATPase	R4TQL5	Phaeocystis_globosa_virus	1.8e-36	40.1

DBSCAN-SWA_347

4827610 : 4827919

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261362.1\|4827610_4827919_-	DUF3263 domain-containing protein	A0A1B3AZ99	Gordonia_phage	4.2e-08	44.9

DBSCAN-SWA_348

4831038 : 4835478

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381267.1\|4831038_4835478_+	cation-translocating P-type ATPase	M1HBF8	Paramecium_bursaria_Chlorella_virus	6.0e-39	27.8

DBSCAN-SWA_349

4843164 : 4844583

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381273.1\|4843164_4844583_+	serine hydrolase	A0A2P1JQM9	Mycobacterium_phage	4.5e-12	27.6

DBSCAN-SWA_350

4848216 : 4851584

Lactobacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381276.1\|4848216_4849437_+	peptidoglycan DD-metalloendopeptidase family protein	O03937	Lactobacillus_phage	1.1e-11	30.2
WP_014381277.1\|4849420_4850461_-	hypothetical protein	NA	NA	NA	NA
WP_014381278.1\|4850600_4851584_-	NAD-dependent epimerase/dehydratase family protein	A0A2K9L4U8	Tupanvirus	3.5e-32	30.7

DBSCAN-SWA_351

4857027 : 4857795

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381283.1\|4857027_4857795_-	SGNH/GDSL hydrolase family protein	A0A160DD06	Gordonia_phage	2.1e-08	30.3

DBSCAN-SWA_352

4863715 : 4869814

Myeloproliferative_sarcoma_virus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085978389.1\|4863715_4865953_+	protein kinase	Q83745	Myeloproliferative_sarcoma_virus	2.5e-09	28.2
WP_036396584.1\|4866308_4867172_+	hypothetical protein	NA	NA	NA	NA
WP_134770507.1\|4868695_4869814_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	6.6e-35	32.6

DBSCAN-SWA_353

4887382 : 4888681

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956036.1\|4887382_4888681_-	adenylosuccinate synthase	A0A291AUF9	Pandoravirus	3.8e-66	34.4

DBSCAN-SWA_354

4900218 : 4900758

Prochlorococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261506.1\|4900218_4900758_-	orotate phosphoribosyltransferase	Q58MW1	Prochlorococcus_phage	2.5e-16	44.4

DBSCAN-SWA_355

4903937 : 4906484

Cronobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261516.1\|4903937_4906484_-	ATP-dependent chaperone ClpB	K4FB40	Cronobacter_phage	7.5e-119	35.6

DBSCAN-SWA_356

4909722 : 4913448

Yellowstone_lake_phycodnavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261532.1\|4909722_4910901_-	molecular chaperone DnaJ	A0A0P0YMJ9	Yellowstone_lake_phycodnavirus	3.0e-14	27.4
WP_009954032.1\|4910950_4911592_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_009954031.1\|4911588_4913448_-	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	1.1e-143	50.3

DBSCAN-SWA_357

4928014 : 4934312

Escherichia_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261569.1\|4928014_4928890_-	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	4.6e-92	56.4
WP_009954015.1\|4928913_4929288_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_009954014.1\|4929317_4930073_-	maleylpyruvate isomerase family mycothiol-dependent enzyme	NA	NA	NA	NA
WP_009954013.1\|4930173_4930830_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_009954012.1\|4931069_4932392_+	MHS family MFS transporter	Q6JIH2	Burkholderia_virus	4.1e-44	32.2
WP_080552513.1\|4932410_4932875_-	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_008261583.1\|4932986_4934312_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	1.7e-69	36.3

DBSCAN-SWA_358

4939493 : 4943514

Saccharomonospora_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261591.1\|4939493_4940066_-	dCTP deaminase	I4AZP2	Saccharomonospora_phage	2.2e-79	76.9
WP_193375127.1\|4940095_4940731_-	hypothetical protein	Q9ZX60	Mycobacterium_phage	1.8e-21	45.9
WP_014381318.1\|4941051_4943514_-	N-6 DNA methylase	J7I0U9	Acinetobacter_phage	1.4e-32	26.7

DBSCAN-SWA_359

4947209 : 4952729

Rhodococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080687381.1\|4947209_4949360_-	bifunctional DNA primase/polymerase	G9FHG8	Rhodococcus_phage	1.4e-20	29.4
WP_014381325.1\|4949920_4950154_-	hypothetical protein	NA	NA	NA	NA
WP_148278284.1\|4950150_4950336_-	hypothetical protein	NA	NA	NA	NA
WP_014381327.1\|4950470_4951172_-	hypothetical protein	NA	NA	NA	NA
WP_036459781.1\|4951168_4951426_-	hypothetical protein	NA	NA	NA	NA
WP_014381329.1\|4951586_4952729_+	hypothetical protein	W0LP87	Mycobacterium_phage	9.6e-74	40.2

DBSCAN-SWA_360

4977379 : 4978207

Acanthocystis_turfacea_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956078.1\|4977379_4978207_-	glycoside hydrolase family 16 protein	M1I0P8	Acanthocystis_turfacea_Chlorella_virus	3.5e-09	33.3

DBSCAN-SWA_361

4994247 : 4995657

Mycobacterium_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381361.1\|4994247_4995657_-\|protease	type VII secretion-associated serine protease mycosin	V5UPA7	Mycobacterium_phage	4.5e-73	40.1

DBSCAN-SWA_362

5000575 : 5008010

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381364.1\|5000575_5004565_-	type VII secretion protein EccC	V5UPA0	Mycobacterium_phage	2.8e-96	26.7
WP_009952519.1\|5004561_5006181_-	type VII secretion protein EccB	NA	NA	NA	NA
WP_085981114.1\|5006177_5008010_-	type VII secretion system ESX-3 AAA family ATPase EccA3	V5UQM2	Mycobacterium_phage	3.5e-102	42.0

DBSCAN-SWA_363

5025698 : 5027387

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954756.1\|5025698_5027387_-	acyl-CoA synthetase	A0A2H4PQM9	Staphylococcus_phage	2.5e-25	28.7

DBSCAN-SWA_364

5044198 : 5046142

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381385.1\|5044198_5046142_+	fumarate reductase/succinate dehydrogenase flavoprotein subunit	M1HTN0	Paramecium_bursaria_Chlorella_virus	7.7e-23	27.4

DBSCAN-SWA_365

5068707 : 5070078

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381399.1\|5068707_5070078_+	PPE family protein	V5UPR1	Mycobacterium_phage	2.7e-06	33.3

DBSCAN-SWA_366

5075700 : 5079792

Yellowstone_lake_phycodnavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957646.1\|5075700_5077347_-	acetolactate synthase large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	2.8e-34	24.8
WP_026071133.1\|5077427_5078846_+	NADP-dependent succinic semialdehyde dehydrogenase	NA	NA	NA	NA
WP_009957644.1\|5078850_5079792_-	R2-like ligand-binding oxidase	A0A1V0CNG9	Kaumoebavirus	1.9e-06	27.3

DBSCAN-SWA_367

5094046 : 5095276

Cronobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381411.1\|5094046_5095276_-	TerC family protein	K4F9T9	Cronobacter_phage	2.8e-34	33.8

DBSCAN-SWA_368

5099129 : 5100647

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381415.1\|5099129_5100647_-	long-chain fatty acid--CoA ligase	Q75ZG1	Hepacivirus	1.1e-32	29.7

DBSCAN-SWA_369

5104410 : 5107402

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381418.1\|5104410_5105616_-	alpha/beta hydrolase	A0A088FQA2	Mycobacterium_phage	7.3e-48	39.3
WP_008261863.1\|5105784_5106447_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_014381419.1\|5106673_5107402_-	alpha/beta fold hydrolase	A0A1D8EUH4	Mycobacterium_phage	1.2e-05	36.0

DBSCAN-SWA_370

5135281 : 5137270

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381440.1\|5135281_5137270_+	M13 family metallopeptidase	A0A1V0SHG2	Klosneuvirus	7.8e-87	29.5

DBSCAN-SWA_371

5146494 : 5147151

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381446.1\|5146494_5147151_-	O-methyltransferase	S5YRC3	Mycobacterium_phage	7.5e-47	51.9

DBSCAN-SWA_372

5173789 : 5178459

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957279.1\|5173789_5175376_-	long-chain-fatty-acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	3.6e-34	28.7
WP_014386033.1\|5175570_5176251_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_008261971.1\|5176355_5176796_-	SRPBCC family protein	NA	NA	NA	NA
WP_044059224.1\|5176855_5177332_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_009957284.1\|5177346_5178459_+	alcohol dehydrogenase catalytic domain-containing protein	A0A0K0KVL7	Prochlorococcus_phage	2.9e-30	29.3

DBSCAN-SWA_373

5196773 : 5197517

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956630.1\|5196773_5197517_-	glucose 1-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	7.8e-16	31.6

DBSCAN-SWA_374

5219635 : 5220961

Cotesia_sesamiae_Mombasa_bracovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956657.1\|5219635_5220961_-	cytochrome P450	I6WI04	Cotesia_sesamiae_Mombasa_bracovirus	4.6e-19	22.9

DBSCAN-SWA_375

5237772 : 5240703

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956680.1\|5237772_5238612_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	5.2e-16	25.6
WP_008262137.1\|5238601_5239420_+	ABC transporter permease	NA	NA	NA	NA
WP_008262140.1\|5239653_5240703_+	esterase family protein	A0A2I6B0H1	Macacine_betaherpesvirus	5.5e-124	67.0

DBSCAN-SWA_376

5250629 : 5258040

Yellowstone_lake_phycodnavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957107.1\|5250629_5252366_+	oxalyl-CoA decarboxylase	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	3.3e-25	25.7
WP_009957108.1\|5252349_5253279_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_009957109.1\|5253607_5254363_+	L,D-transpeptidase	NA	NA	NA	NA
WP_020188392.1\|5254473_5258040_+	thioester reductase domain-containing protein	A0A1V0SBX8	Catovirus	1.2e-10	24.2

DBSCAN-SWA_377

5263141 : 5268541

Gordonia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957116.1\|5263141_5265136_-	acyltransferase family protein	A0A166XZF2	Gordonia_phage	9.0e-43	37.7
WP_009957119.1\|5265369_5266800_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_009957120.1\|5266828_5268541_-	thiamine pyrophosphate-binding protein	G9E525	Ostreococcus_lucimarinus_virus	1.9e-12	23.5

DBSCAN-SWA_378

5279783 : 5282470

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381511.1\|5279783_5281313_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	1.0e-33	26.6
WP_014381512.1\|5281327_5282470_+	NDMA-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	2.2e-30	27.8

DBSCAN-SWA_379

5291467 : 5293039

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381518.1\|5291467_5293039_-	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	1.9e-27	24.8

DBSCAN-SWA_380

5322472 : 5324743

uncultured_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381528.1\|5322472_5324743_+	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	3.1e-92	37.9

DBSCAN-SWA_381

5349839 : 5350733

Prochlorococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953137.1\|5349839_5350733_-	fructose bisphosphate aldolase	A0A0K0KVJ8	Prochlorococcus_phage	1.9e-08	29.6

DBSCAN-SWA_382

5369286 : 5371613

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381539.1\|5369286_5370774_-	type VII secretion protein EccB	V5UN45	Mycobacterium_phage	4.5e-71	36.7
WP_014381540.1\|5370776_5371613_-	transglycosylase	A0A1L2JY60	Aeribacillus_phage	1.8e-13	42.7

DBSCAN-SWA_383

5380380 : 5381823

Mycobacterium_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957441.1\|5380380_5381823_-\|tRNA	CCA tRNA nucleotidyltransferase	A0A249XS88	Mycobacterium_phage	4.8e-62	37.1

DBSCAN-SWA_384

5392639 : 5394000

Orpheovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381550.1\|5392639_5393650_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	1.4e-68	47.6
WP_008262471.1\|5393646_5394000_+	thioredoxin	A0A1J0GW78	Streptomyces_phage	1.5e-25	56.7

DBSCAN-SWA_385

5397393 : 5398209

Natrialba_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071093.1\|5397393_5398209_-	ParA family protein	Q8JL10	Natrialba_phage	5.0e-24	33.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_016946

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection