CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_016947	Mycobacterium intracellulare MOTT-02, complete sequence	7 crisprs	DEDDh,cas3,csa3,DinG,cas4,WYL	1	3	377	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_016947_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016947_1

27124-27209

Orphan

Consensus_repeat	Method
CCGCCCTGCCCCTGGTCGGGGTAGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_016947_1

>merge|NC_016947|1|27124-27209|CRISPRCasFinder
CCGCCCTGCCCCTGGTCGGGGTAGCCGCGCTGGTCCTGGTAGCCCGGCTGCGGCGGGTAACCGCCTTGCCCCTGGTCGGGGTAGCC

>NC_016947|1|1|27124-27209|CRISPRCasFinder
CCGCCCTGCCCCTGGTCGGGGTAGCC	GCGCTGGTCCTGGTAGCCCGGCTGCGGCGGGTAA
CCGCCTTGCCCCTGGTCGGGGTAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_016947.1\|WP_008262550.1\|17472_18159_+\|aminodeoxychorismate/anthranilate-synthase-component-II	unknown	unknown	gnl\|CDD\|181107
NC_016947.1\|WP_014378749.1\|18136_20017_-\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	unknown	unknown	gnl\|CDD\|270916
NC_016947.1\|WP_009952764.1\|24162_25677_-\|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl\|CDD\|223704
NC_016947.1\|WP_007771646.1\|25732_26200_-\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|224630
NC_016947.1\|WP_014378755.1\|28388_28826_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|317917
NC_016947.1\|WP_026071090.1\|29990_30254_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|180304
NC_016947.1\|WP_009952753.1\|34570_34993_+\|hypothetical-protein	unknown	unknown	unknown
NC_016947.1\|WP_014378748.1\|16684_17428_+\|DUF881-domain-containing-protein	unknown	unknown	gnl\|CDD\|226396
NC_016947.1\|WP_020188378.1\|22756_24166_-\|FtsW/RodA/SpoVE-family-cell-cycle-protein	unknown	unknown	gnl\|CDD\|279444
NC_016947.1\|WP_014381558.1\|31822_32410_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|379237
NC_016947.1\|WP_080587904.1\|15692_16118_-\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|371225
NC_016947.1\|WP_014381559.1\|32707_34567_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
NC_016947.1\|WP_041297605.1\|20013_21285_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NC_016947.1\|WP_179300602.1\|29268_29766_-\|DinB-family-protein	unknown	unknown	gnl\|CDD\|378981
NC_016947.1\|WP_014378756.1\|28846_29203_-\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|378915
NC_016947.1\|WP_009952750.1\|35460_36456_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NC_016947.1\|WP_014378751.1\|21281_22760_-\|D,D-transpeptidase-PbpA	unknown	unknown	gnl\|CDD\|223839
NC_016947.1\|WP_009952752.1\|35144_35474_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|379642
NC_016947.1\|WP_009952757.1\|30250_31810_+\|long-chain-fatty-acid--ACP-ligase-MbtM	unknown	unknown	gnl\|CDD\|180289
NC_016947.1\|WP_003872098.1\|16273_16555_-\|cell-division-protein-CrgA	unknown	unknown	gnl\|CDD\|178907

Protein	Function_ID	Function_description	E-value
NC_016947.1\|WP_008262550.1\|17472_18159_+\|aminodeoxychorismate/anthranilate-synthase-component-II	gnl\|CDD\|181107	PRK07765, PRK07765, aminodeoxychorismate/anthranilate synthase component II.	7.58336e-154
NC_016947.1\|WP_014378749.1\|18136_20017_-\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.49766e-130
NC_016947.1\|WP_009952764.1\|24162_25677_-\|protein-phosphatase-2C-domain-containing-protein	gnl\|CDD\|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	4.70422e-82
NC_016947.1\|WP_007771646.1\|25732_26200_-\|FHA-domain-containing-protein	gnl\|CDD\|224630	COG1716, COG1716, FOG: FHA domain [Signal transduction mechanisms].	1.27451e-31
NC_016947.1\|WP_014378755.1\|28388_28826_+\|hypothetical-protein	gnl\|CDD\|317917	pfam15599, Imm63, Immunity protein 63. A predicted immunity protein with an alpha+beta fold and a conserved E+G and ExxY motifs. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, which usually contains toxin domains of the Ntox40, Tox-CdiAC and Tox-ARC families. The protein is also found in poly-immunity loci in polymorphic toxin systems.	1.8184e-09
NC_016947.1\|WP_026071090.1\|29990_30254_+\|acyl-carrier-protein	gnl\|CDD\|180304	PRK05883, PRK05883, acyl carrier protein; Validated.	6.01922e-33
NC_016947.1\|WP_009952750.1\|35460_36456_-\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	2.03046e-59
NC_016947.1\|WP_014378748.1\|16684_17428_+\|DUF881-domain-containing-protein	gnl\|CDD\|226396	COG3879, COG3879, Uncharacterized protein conserved in bacteria [Function unknown].	2.98972e-72
NC_016947.1\|WP_020188378.1\|22756_24166_-\|FtsW/RodA/SpoVE-family-cell-cycle-protein	gnl\|CDD\|279444	pfam01098, FTSW_RODA_SPOVE, Cell cycle protein. This entry includes the following members; FtsW, RodA, SpoVE.	2.5414e-104
NC_016947.1\|WP_014381558.1\|31822_32410_-\|acetyltransferase	gnl\|CDD\|379237	pfam13523, Acetyltransf_8, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	4.0443e-47
NC_016947.1\|WP_080587904.1\|15692_16118_-\|PH-domain-containing-protein	gnl\|CDD\|371225	pfam10756, bPH_6, Bacterial PH domain. This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.	4.64631e-16
NC_016947.1\|WP_014381559.1\|32707_34567_+\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00147878
NC_016947.1\|WP_041297605.1\|20013_21285_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.7491e-117
NC_016947.1\|WP_179300602.1\|29268_29766_-\|DinB-family-protein	gnl\|CDD\|378981	pfam12867, DinB_2, DinB superfamily. The DinB family are an uncharacterized family of potential enzymes. The structure of these proteins is composed of a four helix bundle.	8.34185e-10
NC_016947.1\|WP_014378756.1\|28846_29203_-\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	2.19229e-11
NC_016947.1\|WP_014378751.1\|21281_22760_-\|D,D-transpeptidase-PbpA	gnl\|CDD\|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	7.19099e-104
NC_016947.1\|WP_009952752.1\|35144_35474_-\|N-acetyltransferase	gnl\|CDD\|379642	pfam14542, Acetyltransf_CG, GCN5-related N-acetyl-transferase. This family of GCN5-related N-acetyl-transferases bind both CoA and acetyl-CoA. They are characterized by highly conserved glycine, a cysteine residue in the acetyl-CoA binding site near the acetyl group, their small size compared with other GNATs and a lack of of an obvious substrate-binding site. It is proposed that they transfer an acetyl group from acetyl-CoA to one or more unidentified aliphatic amines via an acetyl (cysteine) enzyme intermediate. The substrate might be another macromolecule.	2.49965e-27
NC_016947.1\|WP_009952757.1\|30250_31810_+\|long-chain-fatty-acid--ACP-ligase-MbtM	gnl\|CDD\|180289	PRK05851, PRK05851, long-chain-fatty acid--ACP ligase MbtM.	0
NC_016947.1\|WP_003872098.1\|16273_16555_-\|cell-division-protein-CrgA	gnl\|CDD\|178907	PRK00159, PRK00159, putative septation inhibitor protein; Reviewed.	9.68334e-47

>NC_016947.1|WP_007771646.1|25732_26200_-|FHA-domain-containing-protein
MQGLVLQLTRAGFLMLLWVFIWSVLRILRTDIYAPTGAVMVRRGLALRSTLLPSRQRRHAARYLVVTEGALAGGRITLSGQPVLIGRADDSTLVLTDDYASTRHARLSQRGSEWYVEDLGSTNGTYLDRAKVTTAVRVPIGTPIRIGKTAIELRP
>NC_016947.1|WP_009952764.1|24162_25677_-|protein-phosphatase-2C-domain-containing-protein
MAPVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHLDDDEPGGDLLAKLDNAVRSGNAAIAAQVEAEPELEGMGTTLTAILFAGDRIGLVHIGDSRGYLLRDGELSQITKDDTFVQTLVDEGRITREEAHSHPQRSLIMRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDETILEALQIPDVAEAAYRLIELALRGGGPDNVTVVVADVVDYDYGQTQPILAGAVSGDEDQMTLPNTSAGRASAIRPRDESAKRVAPQPETPHRPRWSRRRMVVVAALAVLLVVAGLTVGWWVIQRNYYVAEYNGRVSIVRGIQGTLLGVPLQRPYLVGCLNARNELALVSYGQSGHPNCQLMTLQDLRRPGQVQVQTGLPGGSLDQAESQLRQLLAEYLLPICPPPRATSPPGSPSTGGTPQSSTTATPSPPTTSSTSASPPPSTSASNGPATSSPAGPTTTSQTVTALPGPPPQPGIDCRTVA
>NC_016947.1|WP_020188378.1|22756_24166_-|FtsW/RodA/SpoVE-family-cell-cycle-protein
MTTQLQPPVAVTPPLPTRRNAELLLLGFASLITVAALLIVEANQTRDLHWDAINYGLVFLVVFGSAHMAIRRFAPYTDPLLLPIVALLNGLGLVMIHRLDLVTNQLSGRHHPSATQQMLWTLVGVVTFALVVTFLKDHRQLARYGYICGLVGLVLLVIPALLPASLSEQNGAKIWIRLPGFSIQPAEFSKILLLIFFSAVLIAKRGLFTSVGKHFMGLTLPRPRDLAPLLAAWVISVGVMAFEKDLGTSLLLYTSFLVVVYLATQRFSWVGIGLVLFVAGSVVAYFIFNHVRVRVQMWWDPFSDPDGSGYQIVQSLFSFATGGIFGTGLGNGQPDTVPAASTDFIIAAFGEELGLVGLASILMLYTIVIVRGMRTAIATRDSFGKLLAAGLASTLALQLFIVVGGVTQLIPLTGLTTPWMSYGGSSLLANYVLLAILARISHSARRPLRAPARHEPPIAAAGTEVIEKV
>NC_016947.1|WP_014378751.1|21281_22760_-|D,D-transpeptidase-PbpA
MNASLRRISVTVMALIVLLLINATMTQVFAADSLRADPRNQRVLLDEYSRQRGQIVAGGQLLAYSVATDNRFRFLRVYPNPATYAPVTGFYSLRYSSTGLERAEDPLLNGSDERLFGRRLADFFTGRDPRGANVDTTIKPRVQQAAWDGMQQGCGGPPCKGAVVALEPSTGKILAMVSSPSYDPNLLSSHDPEVQAKAWQVLRDDPDNPMTNRAISETYPPGSTFKVITTAAALQAGASDTEQLTAAPSIPLPNSTATLENYGGQSCGNEPTVSLQQAFALSCNTAFVQLGMLTGSDALRGMARSFGLDSTPSVIPLQVAESTIGIIPDAAALGMSSIGQKDVAMTPLQNAEIAATIANGGVTMQPYLIDSLKGPDLTTISTTAPYEQRRAVSPQVAAKLTELMVGAEKVAQQKGAIPGVQIASKTGTAEHGTDPRHTPPHAWYIAFAPAQTPKVAVAVLVENGADRLSATGGALAAPIGRAVIQAALQGGP
>NC_016947.1|WP_041297605.1|20013_21285_-|serine/threonine-protein-kinase
MSPRVGVTLSGRYRLQRLIATGGMGQVWEAVDSRLGRRVAVKVLKQEFSQDPEFIERFRAEARTTAMLNHPGIAAVHDYGESQLDGEGRTAYLVMELVNGEPLNSVLKRTGRLSLRHALDMLEQTGRALQVAHAAGLVHRDVKPGNILITPTGQVKITDFGIAKAVDAAPVTQTGMVMGTAQYIAPEQALGHDATPSSDVYSLGVVGYEVVSGKRPFTGDGALTVAMKHIKEPPPPLPAELPPNVRELIEITLVKNPAMRYRSGGPFADAVAAVRAGRRPPRPSQSPPPGRASPAAIPSSPTTRAAAVSPRSAAPRRSRPTTGGHRPPPARRTFSSGQRALLWAAGVLGALAIIIAVLIVINSRGDQQQQPPTVTDTGTPPASAPAPTNTPSGSAGMRLEWPDDGTIGMSGFRGGPAGHGTSQ
>NC_016947.1|WP_014378749.1|18136_20017_-|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase
MTTPQHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREAQNAAALNHPSIVAVYDTGEAETPTGPLPYIVMEYVDGVTLRDIVHTDGPLPPRRAIEIIADACQALNFSHQNGIIHRDVKPANIMISTTNAVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDAVDARSDVYSLGCVLYEILTGEPPFVGDSPVAVAYQHVREDPVPPSQRHDGISPDLDAVVLKALAKNPENRYQTAAEMRADLVRVHNGEKPEAPKVFTDADRSSMLSSNPGSGGPPPTDPLPRQVLADAGEDRTVGSVGRWIVAVAALAVLTIVVVIAFNTFGGGARDVQVPDVRGQVSADAIAALQNRGFKTRTLQKPDSIVPPDHVIGTDPGANASVSAGDEITVNVSTGPEQREVPDVSSLSYSDAVTKLKAAGFTKFKQANSPSTPELLGKVIGTNPPANQTSAITNVITVIVGSGPETKQVPDIAGQTVDIAQRNLTVYGFSKVTQVQVDSPRPAGEVIGTNPPKGQMVPVDSVIELQVSKGNQFVMPDLSGMFWTDAEPRLRALGWTGILDKGADVDAGGSQSHRVVYQNPPAGSGVNRDGIITLKFGQ
>NC_016947.1|WP_008262550.1|17472_18159_+|aminodeoxychorismate/anthranilate-synthase-component-II
MRILVVDNYDSFVFNLVQYLGQLGVDADVWRNDDDRLSDETAAARQFDGVLLSPGPGTPERAGASIGMVRACAAEQTPLLGVCLGHQAIGVAFGATVDRAPELLHGKTSSVHHTNVGVLQGLPDPFTATRYHSLTILPESLPPVLEVTAHTDSGVIMGVRHAELPIHGVQFHPESILTEGGHRMLANWLAVCGLVRNDTLVRRLENDVHAAVRPYFPADPAATDRTSA
>NC_016947.1|WP_014378748.1|16684_17428_+|DUF881-domain-containing-protein
MIQTRQSPWRFGVPVVCALAGLLLAATHGVSGGAEIRGSDAPRLVDLVRETQSSVNRLNAEREELAKKIDTAHGRSSDAALAAMLRRSAQLAGQADMNPVHGPGLVVTLEDAQRDANGRFPRDASPDDLVVHQQDIQAVLNALWSAGAEAIQMQDQRLIATSVPRCVGNTLLLNGRTYSPPYTITAIGNSAAMQAALAAAPLVVLYKQYVVRFGLGYREEVKSDAQVVGHFEPDRLHYAQPNGPIAY
>NC_016947.1|WP_003872098.1|16273_16555_-|cell-division-protein-CrgA
MPKSKVRKKNDFTVSAVSRTPVKVKVGPSSVWFVALFIGLMLIGLVWLMVFQLAAVGSQAPTALNWMAQLGPWNYAIAFAFMITGLLLTMRWH
>NC_016947.1|WP_080587904.1|15692_16118_-|PH-domain-containing-protein
MQQTQWEPHATGIAGCGAAGVLLAIAGVTLITDPPGRVLAGVAAGGLLLFAGMSWRARPKLAITPDGLALRGWFRTQLLQQSDIKIIRIIEFRRYGRKVRLLEVETADGGLVLFSRWDLGTDPLDVLDALTAAGYAGRSQP
>NC_016947.1|WP_014378755.1|28388_28826_+|hypothetical-protein
MVDDKTAHLQSEVNRIAALLNARPIQAGVVLKDDDRNIYIDDDGRYHYDYWERGRQKVDHVGDIDEALYWFACDIAFDIGGSSSARHCPRDQDPRILMWAKQYEVLNRVNPGWATRCVRETAELLRRWGRHDDVALLPNIPGRDG
>NC_016947.1|WP_014378756.1|28846_29203_-|nuclear-transport-factor-2-family-protein
MNVDADAFSKRWAQRWNAHDVDAVLDDFHDDVVFTSPVAAKLLPETQGVVRGKAALRRYWIAALERIPDLRFTVEGVYQGVNTIVIAYRNQNGDLVNEVLIFDGEVIVEGHGTYRVGE
>NC_016947.1|WP_179300602.1|29268_29766_-|DinB-family-protein
MTEPCAGCGFAYDLRRAASVRHDIRALAAEAVVLLSNNKIDVRSRSRPDVWSPLEYACHLRDVLLVQRERVLAARRTNGHDCASMGRGERAEHDGYSEQDPAEVARQLADAAALFSNVLARLSADDWDRTVIYHYPETHERSLRWVAVHTVHELQHHLLDIRRQL
>NC_016947.1|WP_026071090.1|29990_30254_+|acyl-carrier-protein
MTSFNPPVPSTVDDQLVSVLRDDLDLKFESVTAATRLIDVLGMDSVAFAAGLVAIEERFGTQLSEEDLLTCTTVGDLQAAIGVGVDA
>NC_016947.1|WP_009952757.1|30250_31810_+|long-chain-fatty-acid--ACP-ligase-MbtM
MNVLAAAMRDAMTRSPHDLVVLDKDTDKWTARPWPEVHGMAESIATHLLQQDHLGAVGIVGEPTVELVAAIQGAWLAGAAVSILPRPRRGADPAEWAHSTLSRFRGIGVSTVFSHGATLRTLGDAESTLSVSSLAEAARTPASNDLQSHSDSNAAILQGTAGSTGDPRTAVLSPEAVLNNMRGLIERLQLDGSDRACSWLPIYHDMGLAFLLTAVLSGMPLWQAPTGAFSAAPLRWADWLSASAATFTAGPNFGYSMLGRYSGRVSDVDLGALRIAINGGEPVDCEGFQRFADAMAPFGLRASAATPAYGMAESTCAVTMPACGQGLRIDERTESDVRQRYALLGPPIPGMELRISPTHRSADDGVGEVEIRGSSMMTKYFGDPATGSDRGAEWFRTGDIGYLVDGELVICGRSKEVITIAGRNIFPTEIEQVAAQVDGVRHGGVVAVGSKSGAAQSRLLIAAEFVGSDHDVTRSAVIKRVISVCGVTPADVVLMPPGSLPRTSSGKLRRLEVRSQLQA
>NC_016947.1|WP_014381558.1|31822_32410_-|acetyltransferase
MLARELTDITDSVRQVPAPPVPELLPPSRIRVADPDGADAELVAEWMNRPHLVTTWEYDWPVARWRNHLRAQVDGAYSRPLILSINGVDRAYMEIYRAAKDSIAHCYDSRPHDLGLHGAIADEKLVNRGLGPLILRKVIASILAADPACQRIMFDPDHRNTTVRRLCEFLRCEFLGEHDMPNRRMALYALNRPAP
>NC_016947.1|WP_014381559.1|32707_34567_+|hypothetical-protein
MGLPYIDEQALIAEAGGDPWAINASLQAGSPLEISNLAGAFHRAGRCTAEAENAFQQARARFEAAWNHHDGGGHPINDSDEVQRVTKSLGAQSLQLPKIAADLENIAASLADAQKAGAARIATLEAQLKNISDMVSQAVSILQNDKSLSAGEKDALHALINTCEDDALRDTKAALAALQSIRNGYADGLQKSLDNLHAEGYDGAPLHGVDADGVAPPSPAQQAALADIRQATNQAVVDQMAKVRAAQEALSKAAADLYTHGPGSPEGEAASAKLPKLKADLARALDDLGKIPDYNSIDPASVSVSPDGHFTFTYKVNGQPVQAYGQLKNGTGEFFDQATGTYYTFNGGKLTGMRTPDPGKVEATAEPLFTAVTLAAGAPALKAGGEAAFQGLKMLFSREMLEGVTADNVFPRALAGAEERFQAAEQNLASHAPLPGEPVPGTHPLEPPPVEHAPPAPHGDVPVEHAPAGPHVGALPDSPAPVVIDPAHPEFHLDNPLNYMTPELRAMAEAHLTGSGETVLGPFRPPGGGPSYIQVAEDRGASYFSLGDAWDSFTPTEQLAANQHVLDVAISNQDKITLSVPFHRVPPNSFTAAELRYLEAHGYRRIGENTLLPPSEGAR
>NC_016947.1|WP_009952753.1|34570_34993_+|hypothetical-protein
MKTLLEFFLHYFDFLYLDPRYHVTNSTTSGNPLSNASLTLTGPVISWELTNDRGQLGFVIAPTTLAESPDNWFRATLIRQYLDDYDETNVVSPRETVAWIRSNLSRIEQLFIEPETERSCEELLNLAKALAIKYFGPPQG
>NC_016947.1|WP_009952752.1|35144_35474_-|N-acetyltransferase
MTTDKTGAETAVTLEDGKYTIAVEGKTVGLADFADRGEQRVFYHTEIDPAYGGRGLATILVEEALNEARDEGKRIVPVCSMIGTVLKKHPEFDDITDPVTPEITQWVRS
>NC_016947.1|WP_009952750.1|35460_36456_-|pirin-family-protein
MSNLEAAPAEVACAASQRRDASPRVEVLHPREVPLGGPRAIRVQRTLPQRGRSLIGAWCFIDHYGPVAARMDVPPHPHTGLQTVSWLFSGEVEHRDSAGVRAVVRPGELNLMTAGAGICHSEVSVDAGPVLHGVQLWVALPAAARDTARDFAHYAPPVVPLPGAQARVFLGELAGSRSPTKTFSPLLGAQLDLDADAGFDIDVDPTFEHGVLCDSGTVQVDGTSLAIADLAYLSPGHTQLHVRNVGERPARVLLLGGTPFTEELVMWWNFVGRSHEDIVNYRRLWEDDDDRFGAVHGYRGALARLPAPPLPTARLRPRPIPRRKESTNDNR

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Crispr_ID: NC_016947_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016947_2

350395-350475

Orphan

Consensus_repeat	Method
CTGCCGCGCTCGCGATCGACACCG	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NC_016947_2

>merge|NC_016947|2|350395-350475|CRISPRCasFinder
CTGCCGCGCTCGCGATCGACACCGGATCCGATGGGTGCCGACCCGCTTCGCCCGGCTCCGCCGCGCTCGCGATCGACACCG

>NC_016947|2|2|350395-350475|CRISPRCasFinder
CTGCCGCGCTCGCGATCGACACCG	GATCCGATGGGTGCCGACCCGCTTCGCCCGGCT
CCGCCGCGCTCGCGATCGACACCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_016947.1\|WP_008263248.1\|346746_347169_-\|hypothetical-protein	unknown	unknown	unknown
NC_016947.1\|WP_009955084.1\|358007_359309_+\|ergothioneine-biosynthesis-glutamate--cysteine-ligase-EgtA	unknown	unknown	gnl\|CDD\|274583
NC_016947.1\|WP_020188343.1\|349221_350214_+\|DEDDh-family-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|180377
NC_016947.1\|WP_026071057.1\|344458_344896_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|378454
NC_016947.1\|WP_009952026.1\|344910_345672_-\|Rv3717-family-N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|223929
NC_016947.1\|WP_026071055.1\|359311_360616_+\|ergothioneine-biosynthesis-protein-EgtB	unknown	unknown	gnl\|CDD\|274581
NC_016947.1\|WP_014378918.1\|354760_355903_+\|DUF4185-domain-containing-protein	unknown	unknown	gnl\|CDD\|379383
NC_016947.1\|WP_020188345.1\|341678_342989_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|367049
NC_016947.1\|WP_026071056.1\|345770_346115_+\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|234669
NC_016947.1\|WP_008263246.1\|346128_346740_+\|recombination-protein-RecR	unknown	unknown	gnl\|CDD\|234616
NC_016947.1\|WP_008263265.1\|356023_356449_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368014
NC_016947.1\|WP_009955083.1\|357165_357828_+\|sensor-domain-containing-protein	unknown	unknown	gnl\|CDD\|372884
NC_016947.1\|WP_009955087.1\|361325_362291_+\|L-histidine-N(alpha)-methyltransferase	unknown	unknown	gnl\|CDD\|226751
NC_016947.1\|WP_008263260.1\|352463_353729_+\|aspartate-kinase	unknown	unknown	gnl\|CDD\|235843
NC_016947.1\|WP_009952034.1\|353729_354764_+\|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|237845
NC_016947.1\|WP_020188344.1\|347181_347889_-\|glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NC_016947.1\|WP_014381678.1\|347881_349111_-\|Mur-ligase-family-protein	unknown	unknown	gnl\|CDD\|223840
NC_016947.1\|WP_179300610.1\|342985_344377_-\|FAD-binding-protein	unknown	unknown	gnl\|CDD\|223354
NC_016947.1\|WP_008263266.1\|356567_357083_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236092
NC_016947.1\|WP_014378920.1\|360615_361326_+\|ergothioneine-biosynthesis-protein-EgtC	unknown	unknown	gnl\|CDD\|132483

Protein	Function_ID	Function_description	E-value
NC_016947.1\|WP_009955084.1\|358007_359309_+\|ergothioneine-biosynthesis-glutamate--cysteine-ligase-EgtA	gnl\|CDD\|274583	TIGR03444, EgtA_Cys_ligase, ergothioneine biosynthesis glutamate--cysteine ligase EgtA. Members of this bacterial protein family, EgtA, resemble the glutamate--cysteine ligase of the two-step pathway for glutathione (GSH) biosynthesis, but instead are involved in the biosynthesis of the histidine-derived thiol, ergothioneine (EGT). Successful in vitro reconstitution of EGT biosynthesis using EgtBCDE and gamma-L-glutamyl-L-cysteine suggests that this enzyme is a bone fide glutamate--cysteine ligase. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs].	3.78648e-164
NC_016947.1\|WP_020188343.1\|349221_350214_+\|DEDDh-family-exonuclease	gnl\|CDD\|180377	PRK06063, PRK06063, DEDDh family exonuclease.	0
NC_016947.1\|WP_026071057.1\|344458_344896_+\|SRPBCC-family-protein	gnl\|CDD\|378454	pfam10604, Polyketide_cyc2, Polyketide cyclase / dehydrase and lipid transport. This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. It also includes other proteins of the START superfamily.	1.59797e-08
NC_016947.1\|WP_009952026.1\|344910_345672_-\|Rv3717-family-N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|223929	COG0860, AmiC, N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane].	1.06249e-43
NC_016947.1\|WP_026071055.1\|359311_360616_+\|ergothioneine-biosynthesis-protein-EgtB	gnl\|CDD\|274581	TIGR03440, egtB_TIGR03440, ergothioneine biosynthesis protein EgtB. Members of this family include EgtB, and enzyme of the ergothioneine biosynthesis, as found in numerous Actinobacteria. Characterized homologs to this family include a formylglycine-generating enzyme that serves as a maturase for an aerobic sulfatase (cf. the radical SAM enzymes that serve as anaerobic sulfatase maturases). [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs].	1.18609e-151
NC_016947.1\|WP_014378918.1\|354760_355903_+\|DUF4185-domain-containing-protein	gnl\|CDD\|379383	pfam13810, DUF4185, Domain of unknown function (DUF4185).	3.05242e-55
NC_016947.1\|WP_020188345.1\|341678_342989_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|367049	pfam02353, CMAS, Mycolic acid cyclopropane synthetase. This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.	1.0495e-126
NC_016947.1\|WP_026071056.1\|345770_346115_+\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	1.86878e-43
NC_016947.1\|WP_008263246.1\|346128_346740_+\|recombination-protein-RecR	gnl\|CDD\|234616	PRK00076, recR, recombination protein RecR; Reviewed.	8.42319e-112
NC_016947.1\|WP_008263265.1\|356023_356449_+\|hypothetical-protein	gnl\|CDD\|368014	pfam04592, SelP_N, Selenoprotein P, N terminal region. SelP is the only known eukaryotic selenoprotein that contains multiple selenocysteine (Sec) residues, and accounts for more than 50% of the selenium content of rat and human plasma. It is thought to be glycosylated. SelP may have antioxidant properties. It can attach to epithelial cells, and may protect vascular endothelial cells against peroxynitrite toxicity. The high selenium content of SelP suggests that it may be involved in selenium intercellular transport or storage. The promoter structure of bovine SelP suggest that it may be involved in countering heavy metal intoxication, and may also have a developmental function. The N-terminal region of SelP can exist independently of the C terminal region. Zebrafish selenoprotein Pb lacks the C terminal Sec-rich region, and a protein encoded by the rat SelP gene and lacking this region has also been reported. N-terminal region contains a conserved SecxxCys motif, which is similar to the CysxxCys found in thioredoxins. It is speculated that the N terminal region may adopt a thioredoxin fold and catalyze redox reactions. The N-terminal region also contains a His-rich region, which is thought to mediate heparin binding. Binding to heparan proteoglycans could account for the membrane binding properties of SelP. The function of the bacterial members of this family is uncharacterized.	1.36838e-05
NC_016947.1\|WP_009955083.1\|357165_357828_+\|sensor-domain-containing-protein	gnl\|CDD\|372884	pfam14032, PknH_C, PknH-like extracellular domain. This domain is functionally uncharacterized. It is found as the periplasmic domain of the bacterial protein kinase PknH. The domain is also found in isolation in numerous proteins, for example the lipoproteins lpqQ, lprH, lppH and lpqA from M. tuberculosis. This family of proteins is found in bacteria. Proteins in this family are typically between 214 and 268 amino acids in length. There are two completely conserved C residues that are likely to form a disulphide bond. A second pair of cysteines are less well conserved probably form a second disulphide bond. It seems likely that this domain functions to bind some as yet unknown ligand.	2.77776e-36
NC_016947.1\|WP_009955087.1\|361325_362291_+\|L-histidine-N(alpha)-methyltransferase	gnl\|CDD\|226751	COG4301, COG4301, Uncharacterized conserved protein [Function unknown].	1.00294e-160
NC_016947.1\|WP_008263260.1\|352463_353729_+\|aspartate-kinase	gnl\|CDD\|235843	PRK06635, PRK06635, aspartate kinase; Reviewed.	0
NC_016947.1\|WP_009952034.1\|353729_354764_+\|aspartate-semialdehyde-dehydrogenase	gnl\|CDD\|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	0
NC_016947.1\|WP_020188344.1\|347181_347889_-\|glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	7.42828e-115
NC_016947.1\|WP_014381678.1\|347881_349111_-\|Mur-ligase-family-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	1.22309e-79
NC_016947.1\|WP_179300610.1\|342985_344377_-\|FAD-binding-protein	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	6.93565e-40
NC_016947.1\|WP_008263266.1\|356567_357083_+\|hypothetical-protein	gnl\|CDD\|236092	PRK07772, PRK07772, single-stranded DNA-binding protein; Provisional.	3.20741e-05
NC_016947.1\|WP_014378920.1\|360615_361326_+\|ergothioneine-biosynthesis-protein-EgtC	gnl\|CDD\|132483	TIGR03442, TIGR03442, ergothioneine biosynthesis protein EgtC. Members of this strictly bacterial protein family show similarity to class II glutamine amidotransferases (see pfam00310). They are distinguished by appearing in a genome context with, and usually adjacent to or between, members of families TIGR03438 (an uncharacterized methyltransferase) and TIGR03440 (an uncharacterized protein). [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs].	1.59577e-108

>NC_016947.1|WP_020188343.1|349221_350214_+|DEDDh-family-exonuclease
MSAVCWGRPASEPDAGWAVIDVETSGFRPGQARIISLAVLGLDSDGEVEQSVVSLLNPGVDPGPTHVHGLTAAMLEDQPQFADIAPDVIDVLRGRTLVAHNVAFDYAFLAAEAELADIELPVDSVMCTVELARRLDLGVDNLRLETLAAHWSVTQERPHDAFDDAMVLTGVLASALKLARDGDVWLPVHPVTRRRWPNGRVTHDELRPLKVLASRMPCPYLNPGPYVGGRPLVQGMRVALAAEVGRTHEELVERILHAGLAYSEAVDRETSLVVCNDPAPEQGKGYLARKLGVPVISDATFMDCVRAVIGGTSMDEFADTTNSDPQLALF
>NC_016947.1|WP_014381678.1|347881_349111_-|Mur-ligase-family-protein
MVTTRARLALAAGASARWASRVTGRGAGAMIGGLIAMTLDRSVLRQLAANRRTVVVTGTNGKSTTTRMTSAALATLGPVATNAEGANMDAGLVAALAANRHASLAALEVDEMHVPHVSDAVEPSVVVLLNLSRDQLDRVGEINVIERTLRAGLARHPNAVVVANCDDVLMTSAAYDSPNVVWVAAGGSWSNDSVSCPRSGEVIVRERGHWFSTGADFKRPSPQWWFDDQTLHGPDGLSLPMRLTLPGAVNRGNAAQAVAAAVALGADPAAAVAAVSSVDEVAGRYRTVRVGEHDVRMLLAKNPAGWQEALSMVDKRAAGVVISVNGQVPDGEDLSWLWDVRFEHFEQTEVVAAGERGTDLAVRLGYAGVEHTLVHDTVAAIASCPPGRVEVVANYTAFLQLQRALARRG
>NC_016947.1|WP_020188344.1|347181_347889_-|glutamine-amidotransferase
MADSTVRIGLVLPDVMGTYGDGGNALVLRQRLLLRGIPAEIVEITLADPVPESLDLYTLGGAEDYAQRLATRHLIKHPGLQRAAQRGAPVLAICAAVQVLGHWYETSAGERVDGVGMLDATTSPQAARTIGELATRPLLAGLTERLTGFENHRGGTVLGPSASPLGAVVKGAGNRSGDGFDGVVQGSVIATYMHGPCLARNPQLADLLLGSVVGELPPLPMPEVDLLRRERLAAR
>NC_016947.1|WP_008263248.1|346746_347169_-|hypothetical-protein
MTKIRPRLAAGAALVAAFVASSAPSHASPEVLNGRYNVLYADNDKPTAWLFVPCGSDCTLATSQDGGTFVISWEFHLADGRWTHSGTSQAPCPNGASAPVTVNYSFDAVSLAGEGQQTTTDACGPEAGRTFTRSFQLSKA
>NC_016947.1|WP_008263246.1|346128_346740_+|recombination-protein-RecR
MFEGPVQDLIDELGKLPGIGPKSAQRIAFHLLSVEPPDIDRLTAVLAKVRDGVRFCAVCGNVSDNERCRICADPRRDGSQVCVVEEPKDVQAVERTREFRGRYHVLGGALDPLSGVGPDQLRIRELLSRIGERVDDVDITEVIIATDPNTEGEATATYLVRMLRDIPGLTVTRIASGLPMGGDLEFADELTLGRALAGRRAMV
>NC_016947.1|WP_026071056.1|345770_346115_+|YbaB/EbfC-family-nucleoid-associated-protein
MQPGGDMSALLAQAQQMQQKLMEAQQQLANAEVHGQAGGGLVSVVVKGSGEVVAVKIDPSVVDPSDVETLQDLIVGAMADASKQVTRMAQERLGSLAGGFGPPPGQPPAPAPGI
>NC_016947.1|WP_009952026.1|344910_345672_-|Rv3717-family-N-acetylmuramoyl-L-alanine-amidase
MDLRLSRRVGIKLAVGALVAASTAITPAAWGVPSNIAGMVVFIDPGHNGSNDASISRQVPTGRGGTKDCQASGTASAAGYQEHTFTWDTALRVRAELTALGVRTALARANDTGLGPCVDERASMANALHPNAILSIHADGGPPSGRGFHVNYSAPPLNQAQAGPSVQYARIMRDQMQASGIPPANYIGQNGLYGRSDLAGLNLAQYPSVLVECGNMKNPADSALMQSAEGRQKYADAMVRGVAGFLASQGQAR
>NC_016947.1|WP_026071057.1|344458_344896_+|SRPBCC-family-protein
MGQVSADSTILINAEPAATLAAVADYQTVRPKILSPQYSDYQVLQGGQGAGTVAKWRLQATKSRVRDVQVNVDVAGHTVIEKDANSTMVINWTVAPAGPGSSVTVKTTWTGAGGVKGFFEKTFAPLGLKRIQGEVLANLKKELEG
>NC_016947.1|WP_179300610.1|342985_344377_-|FAD-binding-protein
MVPVLGSALSAHKSGVDRLLASYRSIPATSAVRLAKPTSNLFRARTKRDAPGLDTSGLTGVLSVDPETRTADVAGMCTYADLVAATLPYGLSPLVVPQLKTITLGGAVSGLGIESASFRNGLPHESVLEMDILTGAGDLLTASRTQHPDLFRAFPNSYGTLGYSTRLRIELEPVAPFVALRHIRFRSLPALIAAAERIVDTGGQGGTPVDYLDGVVFSADESYLCVGRRTTTPGPVSDYTGKDIYYQSIRHDAPGLEATKDDRLTMHDYFWRWDTDWFWCSRAFGVQDPRVRRFWPRRYRRSSFYWKLISLDRRFGISDRIEARNGRPPRERVVQDIEIPIERTCDFLEWFLDNVPITPIWLCPLRLRDRDGWPLYPMRPDHTYVNVGFWSSVPGGATEGAANRMIEEKVSELDGHKSLYSDSFYSREDFDELYGGEAYNTVKKTYDPDSRLLDLYAKAVQRR
>NC_016947.1|WP_020188345.1|341678_342989_-|class-I-SAM-dependent-methyltransferase
MTTTKEPHRTSHGKLSMAEILEVFAATGRHPLKFTAYDGSIAGNEDAELGLDLRSPRGATYLATAPGELGLARAYVSGDLQAYGVHPGDPYQLLKTLTDRVEFKRPPVRVLANVVRSLGFERLLPVAPPPQEALPRWRRIADGLMHTRTRDAEAIHHHYDVSNTFYELVLGPSMTYTCAVYPDADATLEQAQENKYRLIFEKLRLKAGDRLLDVGCGWGGMVRYAARRGVRATGATLSAEQAKWAQKAIAEEGLADLAEVRHTDYRDVGEAAFDAVSSIGLTEHIGVKNYPAYFGFLKSKLRTGGLLLNHCITRHDNTSTSFAGGFTDRYVFPDGELTGSGRITCDVQDCGFEVLHAENFRHHYAMTLRDWCRNLVENWDAAVSEVGLPTAKVWGLYMAASRVAFEQNNLQLHHVLAAKTDARGDDDLPLRPWWTA
>NC_016947.1|WP_008263260.1|352463_353729_+|aspartate-kinase
MALVVQKYGGSSVANADRIRRVAERIVATKKQGNDVVVVVSAMGDTTDDLMDLAQQVCPAPPPRELDMLLTAGERISNALVAMAIESLGAQARSFTGSQAGVITTGTHGNAKIIDVTPGRLQAALDEGRVVLVAGFQGVSQDTRDVTTLGRGGSDTTAVALAAALRADVCEIYTDVDGIFSADPRIVHNARKLDTVTFEEMLEMAACGAKVLMLRCVEYARRYNIPVHVRSSYSENPGTVVVGSIKDIAMEDPILTGVAHDRSEAKVTVVGIPDIPGYAARVFRALADADVNIDMVLQNVSKVEDGKTDITFTCSRDSGPTAVAKLDALKDEIGFSQLLYDDHVGKVSLIGAGMRSHPGVTATFCESLAEVGVNIELISTSEIRISVLCRDTELDKAVVALHEAFGLGGEESATVYAGTGR
>NC_016947.1|WP_009952034.1|353729_354764_+|aspartate-semialdehyde-dehydrogenase
MVAIGVVGATGQVGQVMRRLLDERDFPATSVRFFASARSQGRKLEFRGQEIEVEDAATADPSGLDIALFSAGKTMSLVQAPRFAAAGVTVIDNSSAWRKDPDVPLVVSEVNFARDAANRPKGIIANPNCTTMAAMPVLKVLHDEAGLQRLVVSSYQAVSGSGIAGVQELSTQARAVVDDAEQLVQDGGAVQFPAPKTYVAPIAFNVVPLAGSLEDDGSGETDEDQKLRHESRKILGIPDLAVSGTCVRVPVFTGHSLSINAEFARPLSPQRARELLDGAPGVKVVDVPTPLAAAGADESLVGRIRQDPGVPDGRGLALFVSGDNLRKGAALNTIQIAELLAAEL
>NC_016947.1|WP_014378918.1|354760_355903_+|DUF4185-domain-containing-protein
MNPRVSSATRFSLLVASLLAPQWFWAAHADPPAPAPEPILQPLAPGQVLRIGPTAGTGTPTGDYGIGATDLCEFVEFPTELLQVCGDSFAGQGVGFGGWYAPVALHVDTASVDDPAGVRYTGVTGIAHPLLADPAPPDSSQLPAGVVQINRRNYLMVTTTKDLEPQSSRLVTAEPARAGWQTIPGSKRPASYQGGSQTQISGYYDPIPTPESPSGWVYIVADSFTRRDPVVLYRATPQTFTDRSRWQGWAAGASGGWGKPPTPLWPDAVGEMCIRQIDGKAVLSYFNAVTGNMEVRVADDPTALGDAPVTTVVQHDEWPEPAESLPPPYDNRLAQPYGGYISPGSTLDELRIFVSQWDTRARVAAPYRVIQFAVNPFKPE
>NC_016947.1|WP_008263265.1|356023_356449_+|hypothetical-protein
MRTSTATAPAAAAAAYRAPRVFQLAAWVAIVAGIVFIVAVIFFTGFILGHRGGHHGHHHHKHHHHAMLHHRGPGGPGGPGGGTQGGPGAPTGPGATTAPASPSPVRPSGMAPGQLPASIFHSAAASHAAPGQAPSVIVLTN
>NC_016947.1|WP_008263266.1|356567_357083_+|hypothetical-protein
MSETPEPQAEPTPAAATTPPAPPPPPRVKPPRLYTAAAWVVIVAGIVFILSSVFFVGAFIWKHHYHCHHHHGMFHPGGPGPGNGPWGPGPGPGNGPWGPGPGGPGSWYGGPGGPGPDNGPWGPGPGGPGLIVPMPPGGPGGPGGPVSGPGISGPGQPTAVSPAPGSPAPRP
>NC_016947.1|WP_009955083.1|357165_357828_+|sensor-domain-containing-protein
MTMRATQVHRAVLTVGFAVAGTVAPAVAAAHPSEPGVVNYAVLGKGSVGNIVGGPMGWESVFTQPGQGPWVDLPECNNWADIGLSEVYDDPDLASFNGAVTQTSANDQTHLVKQAVGVFATPDAAARAFHRVVDRTVGCSGQTTAIHLDNGSTQVWSFDGGPAGPADENWTKQEAGTDRRCFDQTRLRENVLLQAKVCQPGNAGPAVNVLAGAMQNALGQ
>NC_016947.1|WP_009955084.1|358007_359309_+|ergothioneine-biosynthesis-glutamate--cysteine-ligase-EgtA
MTFAPITAAAPRSTGADPAPELKIAELTDSTAVAQYIADGCLVDAPLGRVGLELEAHCHDPAAPHRRPGWDEIAAVLDGLPALPGGSRITVEPGGAVELSGPPADGVLPAIEAMRRDQAVLQPAFAEAGLGLVFLGADPLRPPQRINPGARYRAMERFFATSRSGEAGAAMMTSTASIQVNVDAGPREGWAARVRLAHALGPTMIAITANSPMLGGDFTGWVSSRQRVWGQMDSARCGPILGASGDDPGTDWGRYALKAPVMLVHTPGAEAVTQWVPFADWVDGRVLLGDRRPSIADLEYHLTTLFPPVRPRQWLEIRYLDSVPDALWPAVVFTLVALLDDPTAADAAAEAVAPVATAWDIAARLGLRDRRLYAAANACVAIAAERAPAEVGDAMQRLVDLVEQGRCPGDDFADRVIEHGVTAEVSRAARGGL
>NC_016947.1|WP_026071055.1|359311_360616_+|ergothioneine-biosynthesis-protein-EgtB
MTSRQALADQLTRTRTRTLRLVDFDDAELCRQYDPLMSPLVWDLAHIGQQEELWLLRGGDLARPSMLSPAVEGLYDAFVHSRASRVDLPLLSPDEARAYCRTVRSAVFDALDALPDDPAGDEAAFAYAMVVSHENQHDETMLQALNLRSGPPLLRGTSMLPPARPGLAGTSVLVPGGEFVLGVDPAAEPFSLDNERPGHVVDLPAFRIGRVPVTNGEWRHFIDDGGYDQPRWWSERGWRHRQAAGLTAPQFWNPDAATRTRFGHVEDIPADEPVQHVSYFEAEAYAAWAGARLPTEMEWEKACAWDPSAGVRRRYPWGAQEPCDALANLGGTALRPAPVGAYPAGASAYGAEQMLGDVWEWTSSPLRPWPGFVPMLYERYSQPFFDGDYRVLRGGSWAVEPGILRPSFRNWDHPYRRQIFSGVRLAWDVPKEIA
>NC_016947.1|WP_014378920.1|360615_361326_+|ergothioneine-biosynthesis-protein-EgtC
MCRHLGWLGADVTVSSLVLDPPFGLRVQAYAPRRQKHCLLNADGWGVGFFDAASDGAAPRRWRSQLPLWGDVSFESVAPALRSHCVVAAVRSATVGMPIEVSATAPFTDGQWLLSHNGIVDRAALPATSQAESVCDSAMLAAVIFERGLDALGDTIVEIAAADPRARLNILAANGSRMLATVWGDTLSILRRPDGVVLASEPYDNDSDWEDVPDRHLVEVTAGGVTMTPLDHPKGS
>NC_016947.1|WP_009955087.1|361325_362291_+|L-histidine-N(alpha)-methyltransferase
MTLSLSNHLAADSAYHALRRDVFEGLQKTPKSLPPKWFYDAVGSDLFDQITRLPEYYPTRAEAEILRARAAEIASASEADTLVELGSGTSEKTRLLLDALRARGSLRRFVPFDVDASILSTAAAAIAQEYSGVEIKAVCGDFEEHLTEIPADGRRLFVFLGSTIGNLTPGPRADFLAALSAQMRPGDSLLLGTDLVKDLERLVRAYDDSAGVTAAFNRNVLAVVNRELDADFDVDAFAHVARWNPAEERIEMWLRADRGQRVRVGALELIVDFEAGEEMLTEVSCKFRPEKVSAELAAVGLRRTQWWTDGAGDFGLSLAVK

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Crispr_ID: NC_016947_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016947_3

1528426-1528508

Orphan

Consensus_repeat	Method
CGCCCGGCGGCGCCGCGCTCGCGATCGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_016947_3

>merge|NC_016947|3|1528426-1528508|CRISPRCasFinder
CGCCCGGCGGCGCCGCGCTCGCGATCGGCTTGATCTACGCGCGCCGACCCGCTTCGCCCGGCGGCGCCGCGCTCGCGATCGGC

>NC_016947|3|3|1528426-1528508|CRISPRCasFinder
CGCCCGGCGGCGCCGCGCTCGCGATCGGC	TTGATCTACGCGCGCCGACCCGCTT
CGCCCGGCGGCGCCGCGCTCGCGATCGGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_016947.1\|WP_014382055.1\|1529024_1530149_+\|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl\|CDD\|374736
NC_016947.1\|WP_009953976.1\|1537416_1537947_+\|DUF3558-domain-containing-protein	unknown	unknown	gnl\|CDD\|378803
NC_016947.1\|WP_009953966.1\|1520170_1521301_+\|FAD-binding-protein	unknown	unknown	gnl\|CDD\|180297
NC_016947.1\|WP_009953979.1\|1538705_1539857_+\|exonuclease-SbcCD-subunit-D	unknown	unknown	gnl\|CDD\|223497
NC_016947.1\|WP_008254722.1\|1536850_1537408_+\|DUF3558-domain-containing-protein	unknown	unknown	gnl\|CDD\|378803
NC_016947.1\|WP_026071519.1\|1526474_1526909_-\|HIT-family-protein	unknown	unknown	gnl\|CDD\|238608
NC_016947.1\|WP_009953961.1\|1516551_1517214_+\|hypothetical-protein	unknown	unknown	unknown
NC_016947.1\|WP_026071521.1\|1514452_1515907_+\|MCE-family-protein	unknown	unknown	gnl\|CDD\|224380
NC_016947.1\|WP_008254716.1\|1531044_1532811_-\|sensor-domain-containing-protein	unknown	unknown	gnl\|CDD\|270916
NC_016947.1\|WP_009953977.1\|1538039_1538543_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|224973
NC_016947.1\|WP_009953960.1\|1515949_1516555_+\|hypothetical-protein	unknown	unknown	unknown
NC_016947.1\|WP_009953968.1\|1522388_1526255_-\|bifunctional-diguanylate-cyclase/phosphodiesterase	unknown	unknown	gnl\|CDD\|238923
NC_016947.1\|WP_014382054.1\|1526992_1528381_+\|amidase	unknown	unknown	gnl\|CDD\|171524
NC_016947.1\|WP_008254711.1\|1530428_1531001_+\|hypothetical-protein	unknown	unknown	unknown
NC_016947.1\|WP_009953975.1\|1534902_1536669_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_016947.1\|WP_009953974.1\|1532989_1534906_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_016947.1\|WP_014379578.1\|1539853_1542475_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|227061
NC_016947.1\|WP_009953958.1\|1513311_1514451_+\|MCE-family-protein	unknown	unknown	gnl\|CDD\|273384
NC_016947.1\|WP_009953965.1\|1519337_1520174_+\|uracil-DNA-glycosylase	unknown	unknown	gnl\|CDD\|381681
NC_016947.1\|WP_009953964.1\|1517903_1519271_-\|FAD-binding-protein	unknown	unknown	gnl\|CDD\|273050

Protein	Function_ID	Function_description	E-value
NC_016947.1\|WP_014382055.1\|1529024_1530149_+\|adenylate/guanylate-cyclase-domain-containing-protein	gnl\|CDD\|374736	pfam16701, Ad_Cy_reg, Adenylate cyclase regulatory domain. This domain regulates the activity of Actinobacterial adenylate cyclase in a pH-dependent manner, allowing activation at acidic pH.	8.00421e-95
NC_016947.1\|WP_009953977.1\|1538039_1538543_-\|histidine-phosphatase-family-protein	gnl\|CDD\|224973	COG2062, SixA, Phosphohistidine phosphatase SixA [Signal transduction mechanisms].	1.422e-43
NC_016947.1\|WP_009953966.1\|1520170_1521301_+\|FAD-binding-protein	gnl\|CDD\|180297	PRK05868, PRK05868, FAD-binding protein.	0
NC_016947.1\|WP_008254722.1\|1536850_1537408_+\|DUF3558-domain-containing-protein	gnl\|CDD\|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	4.57725e-31
NC_016947.1\|WP_026071519.1\|1526474_1526909_-\|HIT-family-protein	gnl\|CDD\|238608	cd01277, HINT_subgroup, HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life. Although the biochemical function has not been characterised for many of the members of this subgroup, the proteins from Yeast have been shown to be involved in secretion, peroxisome formation and gene expression.	1.37568e-49
NC_016947.1\|WP_026071521.1\|1514452_1515907_+\|MCE-family-protein	gnl\|CDD\|224380	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism].	6.3405e-66
NC_016947.1\|WP_008254716.1\|1531044_1532811_-\|sensor-domain-containing-protein	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.17318e-119
NC_016947.1\|WP_009953979.1\|1538705_1539857_+\|exonuclease-SbcCD-subunit-D	gnl\|CDD\|223497	COG0420, SbcD, DNA repair exonuclease [DNA replication, recombination, and repair].	1.96044e-62
NC_016947.1\|WP_009953975.1\|1534902_1536669_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.34723e-158
NC_016947.1\|WP_009953968.1\|1522388_1526255_-\|bifunctional-diguanylate-cyclase/phosphodiesterase	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.82523e-82
NC_016947.1\|WP_014382054.1\|1526992_1528381_+\|amidase	gnl\|CDD\|171524	PRK12470, PRK12470, amidase; Provisional.	0
NC_016947.1\|WP_009953976.1\|1537416_1537947_+\|DUF3558-domain-containing-protein	gnl\|CDD\|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	6.49783e-31
NC_016947.1\|WP_009953974.1\|1532989_1534906_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NC_016947.1\|WP_014379578.1\|1539853_1542475_+\|AAA-family-ATPase	gnl\|CDD\|227061	COG4717, COG4717, Uncharacterized conserved protein [Function unknown].	2.14957e-10
NC_016947.1\|WP_009953958.1\|1513311_1514451_+\|MCE-family-protein	gnl\|CDD\|273384	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein. Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis].	1.89831e-71
NC_016947.1\|WP_009953965.1\|1519337_1520174_+\|uracil-DNA-glycosylase	gnl\|CDD\|381681	cd10031, UDG-F5_TTUDGB_like, Uracil DNA glycosylase family 5, includes Thermotoga maritima TTUDGB and similar proteins. Uracil DNA glycosylase family 5 includes Thermus thermophilus HB8 TTUDGB (also called UDGb) which is not only a UDG acting on double-stranded uracil-containing DNA, but also a hypoxanthine DNA glycosylase acting on double-stranded hypoxanthine-containing DNA (except for the C/I base pair), as well as a xanthine DNA glycosylase acting on both, double-stranded and single-stranded xanthine-containing DNA. TTUDGB also excises thymine from G:T mismatched DNA, and removes analogs of uracil from DNA, including 5-hydroxymethyluracil (hmU) and 5-fluorouracil (fU). This subfamily also contains Bradyrhizobium diazoefficiens family 5 homolog Blr5068 (UdgB) which has been found to efficiently excise uracil from ssDNA and dsDNA. Uracil-DNA glycosylases (UDGs) initiate repair of uracils in DNA. Similar to family 4 UDGs, members of this family possess four conserved cysteine residues required to coordinate the [4Fe-4S] iron-sulfur cluster. Uracil in DNA can arise as a result of mis-incorporation of dUMP residues by DNA polymerase or via deamination of cytosine. Uracil in DNA mispaired with guanine is one of the major pro-mutagenic events, causing G:C->A:T mutations. Thus, UDG is an essential enzyme for maintaining the integrity of genetic information. UDGs have been classified into various families on the basis of their substrate specificity, conserved motifs, and structural similarities. Although these families demonstrate different substrate specificities, often the function of one enzyme can be complemented by the other.	1.2484e-113
NC_016947.1\|WP_009953964.1\|1517903_1519271_-\|FAD-binding-protein	gnl\|CDD\|273050	TIGR00387, Glycolate_oxidase_subunit_glcD., glycolate oxidase, subunit GlcD. This protein, the glycolate oxidase GlcD subunit, is similar in sequence to that of several D-lactate dehydrogenases, including that of E. coli. The glycolate oxidase has been found to have some D-lactate dehydrogenase activity. [Energy metabolism, Other].	9.15276e-135

>NC_016947.1|WP_014382054.1|1526992_1528381_+|amidase
MNDDLAFAGAAAQARMLADGELTAPELLEVYLERIAQLDSQLRCYRVVLADKARYEAAVAQDRLDAGERLPLLGVPVAIKDDVDVAGEVTTFGSGGHRPAVSSDAEVVRRLRAAGAVIVGKTNVPELMMLPYTESLTFGATRNPWDPRRTPGGSSGGSAAAVAAGLAPLALGSDGGGSIRIPATWCGVFGLKPQRDRVSLEPHDDAWYGLSVNGPIARTVIDAAVFLDATSTVPGPEGEFVSAATRSPGRLRIALSTKVPTPLPVRVGKRELAAVDEAGALLRDLGHDVITADPEYPASAILTNYLPRYLRGICDDADALAHPERLEPRTRNMARLGSFFSDRRMESLRAAEGAVVSRIQAIFDDVDVVVTPGTATGPSRIGAYQRRGAVSTLLRVGQYVPYQQVWNLTGQPAAVVPWDLDADGMPMSVQLVGRPYDEATLLSLSAQIEAARPWALRRPPVS
>NC_016947.1|WP_026071519.1|1526474_1526909_-|HIT-family-protein
MSCVFCAVVAGEAPAIRIYEDDDYLAILDIRPFTRGHTLVLPKRHSVDLTDTTPETLAGMVTLGQRIARAARTTELADATNIAINDGSAAFQTVFHIHLHVLPRRNGDKLSVAKGMLVRRDPDRDATGQILRNALARIDASQPD
>NC_016947.1|WP_009953968.1|1522388_1526255_-|bifunctional-diguanylate-cyclase/phosphodiesterase
MYGVAGVLIVLSSFWGWRGPYGTHPINGFVIAMCLAIAAAYAARAARFKPRRQRYGWLALVTALLGWAAGEVIWAFYDVRPEFDHATHPAATEFVLLLWPVGAMTSLVLLSQLSRKSPRRLLLDGLIVATSLFVIAWVFVVEAQLQEHSGARLVTSAEVFADIVQVTTAILMLSRARPGDRPSRSLLAAGVATICIADMALVFYTGIASYHTGGVGDLVRVAGLALLALAALAAAHERPAPAPPDETEFRARLWLPYLPLILAAAAGWAHAAGHSIHDPMLAALGILVAAVLARQFVVLVDNQNLLSEVAREAFRDNLTGLANRALFLQRLEQAVARRHPNGMPIAVLCLDLDNFKSVNDALGHPAGDELLVRVAGRLTAALGESGTIARLGGDEFAAVIEASVQESQAAAHRILDAFTGAILIDGIPIMVRPSIGFTVCTGASACTVDQLLRHADLAMYAAKREGGQCIRSFMPDLPLPYAFPASPDSGESDVAPPVDGGGGVATPQASPPVSDVATPTTNSPSGDVSDDAPRPPRGIRVGFAVLAVGVIAFAASSVAHPDAGHGMFSATTLYSALTVLAAGLVVLRAYRVSADRLAWSLIAAGMAFSAAGDIVYALFVPNGRSPSVADPVYLAYYPLVYAGLLLLMRARFKRLPIPIQLDSLVCALTLAAVAAAVTEGPMRAATSRTPATVWMGLVYPWIDLVLLALAAGMLPILGWRNDFRWALLMTGLVVFAVADVAYLFQTTAGSYRVGTLLDACWPASSLLIAMASWSPSSPTAPVPRHRFSPYVTPVTTSVVALGVIVLAHHSRPAATLAALSLVVATARFSLTFRDVSLLHTNAKHAMTDELTALPNRHSLASALTALPTTAPGPTSIPGRARARRALLLLSLSDFHEITDSIGRHFGDELLCHIANRLSGSVRRDDMLARVGDDQFAVLLADGANLTAASAQAGRLLEALSEPIALDPITVQVEGRIAIALCPDHCDHPQELLGRAETAMAHAESARSKIAVYDSSFEVYRNNDPNLIEDLRTALFDTDELKLHYQPKIDGRDGSVHSVEAVLRWQHPTRGTLLPEEVLPVAERAGLMRKISNRTLSMALKQVRCWREQGITLTVAVNLSTTNLLDIELVGTVERLLANYDLPADALILEITESALVDSARSRNTVAALQRLGIRISLDDYGTGWSSLARLQEVSVDELKLDRIFVTRLDHDARSVAIVRSTVALAHNLGADLVAEGVENKGTLDALHRYGCMITQGYVHTAPLPPDELRNWIANHTPEPHTSQSHRRA
>NC_016947.1|WP_009953966.1|1520170_1521301_+|FAD-binding-protein
MSEILVSGASVAGTAAAFWLGRHGHSVTVVERHTGPRPGGQAIDVRGPALTVLDRMGLLAAAEKRKTQIRGSSVVDRDGNELSRDTESTPTGGRIDSPDIELLRDDLVELLYGASQWTTDYLFDDTITALEADGAAVRVTFERAAPREFDLVVGADGLHSNVRRLVFGPEEDFIERLGTHAAIFTVPNFLDLDHWQMWHYGDSTMAGIYSARHNAEARAMLGFMDPELRIDYRDTEAQFAELERRMAGEGWVRPQLLEYMRTAPDFYFDEMSQIKMDRWSHGRVVLVGDAGYCCSPLSGQGTSVALLGAYVLAGELKSATSDGTADHERGFANYHREFADYVQRNQWLVVDNIPGGAPIPQEVFDRIVSSITLKDY
>NC_016947.1|WP_009953965.1|1519337_1520174_+|uracil-DNA-glycosylase
MQDVHVLDHPRTGQPFDSPVGAGTGWPGDPATPQTPVAADAARVVALAEQATSIPELDALVSVCRACPRLVDWREEVARVKRRAFADQPYWGRPVPSWGAARPRLLIVGLAPAAHGANRTGRMFTGDRSGDQLYAALYRAGLVNQPTSVDAADGLRTNQIRIVAPVRCAPPANAPTPAERDTCWPWLQAEWQLVADHVRVVVALGGFGWQIALRLPGTSGRAAGPKPRFGHGAVADLAPGVRLLGCYHPSQQNMFTGRLTPAMLDDIFRDAKELAGIK
>NC_016947.1|WP_009953964.1|1517903_1519271_-|FAD-binding-protein
MSSDALASLIADLPDGMVVTDPTVTEGYRQDRAFDPSAGKPLAVVRPRRTEEVQTVLRWATANRVPVVPRGAGSGLSGGATALDNCIVLSTEKMRDISVDPVTRTAVCQPGLFNAEVKKAAAEHGLWYPPDPSSFEICSIGGNIATNAGGLCCVKYGVTTDYVLGMQVVLADGTAVRLGGPRLKDVAGLSLTKLFVGSEGTLGVVTEVTLRLVPKQNASSVVVATFASVQDAVDAVLGVTARLRPSMLEFMDSVAINAVEDTLRMDLDRGAAAMLVAGSDERGRAGSEDAEIMAKVFAENAATEVFSTDDPDEGEAFVVARRFCIPAVEAKGSLLLEDVGVPLPALGRLVTGIAGIAAERDLMISVIAHAGDGNTHPLIVYDPADADMTERAHLAFGEIMDLAVGLGGTITGEHGVGRLKRPWLAGYLGPEVMDLNRRIKQALDPQGILNPGSGI
>NC_016947.1|WP_009953961.1|1516551_1517214_+|hypothetical-protein
MKFPKLLRRADDHTNVASSEEAPATPGPTAIAGDKPDTDVATTEVDESGDRQSSTPAKHHIRWARAIVYALLPGLALSLAVAAGFLKWQGGSARTAQLAATESVRTATESTIALLSYRADSVEKDLEAARSRLTGKFLNAYTSLTHDVVIPGAKQKHISASATVPAAAPIEATGSHAVVLLFVNQTVTIGQDSPTNSASSVRVTLDKVDGRWLIAEFDPI
>NC_016947.1|WP_009953960.1|1515949_1516555_+|hypothetical-protein
MREAVDFHASPGGDVVDADGDTIESDIDPTENASTPRSAESVFHLRPTIRVCLTIVVALSVLVGWLGFRSYQTHQAQIQRNQFLQVARQGALNLTTIDWRHADTDVQRILDGATGQLHDDFAKRSKPFIEVVKQAKAITVGTISSAGLESETADTAQVLVAMTVQTSDAAASDQAPRAWRMRIFVQKTDGQVKVSNVEFVP
>NC_016947.1|WP_026071521.1|1514452_1515907_+|MCE-family-protein
MRLGLQIWIKLSIFAAVSGIAAAVTVFGYIKVENLIPGLGQYKVTVQLSQAGGLYKRANVTYRGTYVGRVKDVRITPTGVDAVLLLKSGLDIPSDLDAQVHSQSSVGEQYVSLLPRNGNSRPLRDGDVIPENHTSVPPDINTLLNATNRALEAIPRDNLKTVIDESYTAVGGLGPELSRIVKGSTALATDARKNVDSLTALIDQSQPVLDSQAGTSPSILAWSKHLATITDQLQGHDAAVAGVLEKGGPAANEVRQLFDRLRPTLPIMLANLVSIGQVAVTYRNDIEQLLVLLPQATAVQAGGDVPNMGTKQAYRGYYLDFNLNLNLPPLCTTGFLPAQQHRVPEVDYPDRPAGDLYCRAPQDSPLAVRGVRNVPCETVPGKRAPTVKMCESNEHYVPLNDGFNWKGDPNATLSGQGIPQLPPGSPPAVAGPPASAPPPIAAAQYDPATGTYIGPDGHQYTQSDLAQTAPKDKTWQTMLMPPGS
>NC_016947.1|WP_009953958.1|1513311_1514451_+|MCE-family-protein
MRRSRWVGVTAGLLVALAGSLLSGCGWRGLNSILLPGTAGGGPGSYEVKAQMPDVVNVQPNSRVQVGDVTVGTVTNVEREGWHALLTMRLDGNVKLPANATAKIGQTSLLGSLEVELAAPTNVPAEGRLRNGSLIPLSAAGEYPTTEQTLAALSLVLNGGGLGQVQDITKTLSTAFAGREKDLKNLIQQLDQFIGHLNEQTDDIIKATDSVNNLAGQFAEQKPVVDRLLSTLPDALAVLKDERAKLADAADQLGKFSALAADSVNQTKDALVQELKDLGPVLESLANAGPSLTRSLSFFTVFPWVKEPLTNWLRGDYANLTLIVDLTLSRIDSALFTGTRFEGNLTELELQWGRTIGQQPSPYTKGNPLIIPYHLDQGP
>NC_016947.1|WP_014382055.1|1529024_1530149_+|adenylate/guanylate-cyclase-domain-containing-protein
MHDGDDHTIDDLLEGLEGTARTERAELVRWLFEQGITAEEIRATNPPLLLATRHIIGDDGTYVSTREISETHGIDLGLLQRVQRAIGLVRVDDPDAAVHMRADGEAAAFTQRFVELGLDPEHVILVVRVLAEGLSRTAEVMRYSALSAIMRPGASELEIAQASKALVTKIAPMLGPMIQHMLFMQLRHMMETEAVNAAERAAGKPLPGARQISVAFADLVGFTRIGEAVTPEELGHLANRLAILARDMTVPPVRFIKTIGDAVMFVCPEPQPLLDVVLKLVEAVDSDNDFPRLRAGVASGMAVSRAGDWFGSPVNVASRVTSVARPGTVLAADSVWEVIGERGEFSASFAGSRHLKGIKGEVKLFRIRRGDAED
>NC_016947.1|WP_008254711.1|1530428_1531001_+|hypothetical-protein
MKAHHTHGRRYGRPGGWQQAQQPDAGDAAEWFAGRLPEKWFDGDPTVIVDREEITVMGRLPDTASAESGESEARAAGRASRFREETRSERMHIADEAQDRYGRKVSWGVEVGSERILFTHIAVPVMTRLKQPERQVLDTLVDAGVARSRADALAWSVKLVGEHAEEWLAKLRDAMTAVDDLRAQGPDLQS
>NC_016947.1|WP_008254716.1|1531044_1532811_-|sensor-domain-containing-protein
MSDEQASRAGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLSESFSRDPVFRERMKREARTAGRLQEPHVVPVHDYGEIDGQIFLEMRLVEGTDLDSVLKRFGPLTPPRAVAVITQIASALDAAHAAGVMHRDVKPQNILVTADDFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSDAEVTYRADIYALACVLFECLTGAPPYRADSAGMLVSAHMMDPIPAPSQRRPDIPKAFDAVIARGMAKRPEDRYASAGDLALAAKQALSHPDQDRAATILRRSQEAALPTAVNPDPRLSTAPPPRPYQPAFNTPPPSPSAAPYYQGASANWGGPPPQFANATPWGQPPPRPRRNVWLIVAAVAVVFVLLGSGLGIWLVTRPDPEPPPPAPLEADRLSALLLGPSDINTVMGSSTMQPGKPITSTDHSAVTVSTPDCQGALYTTQDPVYAGTGYTSVSGLVSSEPGDNYDHWVNQAVVLFPSADKAKSFLENSAEKWKGCAGKTVTVTNKSKTYRWTFAQVQGSPPKITLMDTQEGADGWECQRALTVANNVIVDINACGYHISDQGAQIADKIAARIADE
>NC_016947.1|WP_009953974.1|1532989_1534906_-|ABC-transporter-ATP-binding-protein
MTSSTSTATRGVAPPPAGRSRDFWGSAARLVKRLAPQRRLSIAVITLGLAGTVIGVIVPRILGHATDLLFNGVIGRQLPAGISKAQAVSAARGRGENTFADLLSGMNVVPGHGVDFGAVARTLTLALALYLVSSVLIWAQARLLNLTVQRTMVALRSDVEDKIHRLPLSYFDGRQRGELLSRVTNDIDNVQSSLSMTISQLLTSVLTVVAVLAMMLSISPLLVGITVLTVPLSLLATRAIARRSQRLFLAQWASIGRLNAHIEETYSGFTVVKTFGHQAAAREQFRALNGDVYRSSFGAQFFSGLVAPATTFIGNVGYVAVAVVGGLRVATGHITLGDIQAFIQYVRQFNSPLSQLAGMYNTLQSGVASAERVFALLDEPEESPDPQPAAPPPADGAPRWTGRVEFAHVSFAYRPGVPVIDDLSLVAEPGSTVAIVGPTGAGKTTLVNLLMRFYEVDSGQILLDGVDIATLDRHSLRSRIGMVLQDTWLFDGTIAQNIAYGRPEAGDGEVVAAAEAAHVDPFVRSLPDGYQTRVSGDGANISAGEKQLITIARAFLARPQLLILDEATSSVDTRTEALIQRAMCDLRRDRTSFIIAHRLSTIRDADRILVIEGGRIVEQGNHAELLARRGAYYAMTRA
>NC_016947.1|WP_009953975.1|1534902_1536669_-|ABC-transporter-ATP-binding-protein
MLLALLRQYIQPYRRLVAMLMVLQLISNLASLYLPTVNAAIIDEGVAKGDTAAIVRLGIVMLGATGLQVLCSVGAVYFGSRTGMGFGRDLRAAVFEHVLTFSERESARFGAPTLLTRSTNDVRQIQYLVQITATVLVTAPIMCLGGIVMALRQEAALTWLLLVSVPVMAVANYWVMSHMLPLFRRMQGLIDGINRVMRDQLAGVRVVRAFAREGFERDRFARANAALSNTALTAGNWQALMLPVTTLTINVSSVALIWFGGQRIDRGQMQVGSLTAFLAYFTQILMAVLMATMTLVVLPRASVCAERITEVLTTRPAVTDPPGPASPPGKITGVVRLDGATFTYPGADRPVLQDISFIARPGTTTAIVGSTGSGKSTLISLMCRLYDVTGGTVLVDDIDVRDYHTELLWSAIGLVPQRGYLFSGTIADNLRYGAAPGHDITGDEMWEALRVADADGFVRAHPDGLQMRVAQGGINFSGGQRQRLAIARAVIRRPAVYLFDDSFGALDVHTDARVRAALKQISKEATVIVVTQRVSTAAQADQVIVIDGGRLVGAGTHESLLADSATYAEFADSQAVGALPSGHVGGAQ
>NC_016947.1|WP_008254722.1|1536850_1537408_+|DUF3558-domain-containing-protein
MRRSARALALVASALTILIPAVAACSDSGGNKPGATASSTPQKGQGNHGPMFPQCGGISDQTVAELTRVTGLINTARNSVGCQWLAGGGILGPHFSFSWYRGSPIGRERKTEELSRASVDDININGHGGFIAVGNEPNLGDSLCEVGIQFQDDFIEWSISFSQKPFPPPCDIAKELARQSIANSK
>NC_016947.1|WP_009953976.1|1537416_1537947_+|DUF3558-domain-containing-protein
MRAAAVVLLAALLVLTGCSRSIGGNAVKAGGNVPRNNNSQQQYPNLLKECEVLTSDILAKTVGADPLDIQSTFVGAICRWQAANPAGLIDITRFWFEQGSLSNERKVAEFLKYKIESRPIAGIDSIVMRPDDANGACGVASDAAGVVGWWVNPQAPGIDACGQAIKLMELTLATNS
>NC_016947.1|WP_009953977.1|1538039_1538543_-|histidine-phosphatase-family-protein
MTAERTLLLMRHAKSDYPAGVADHDRPLAPRGVRQAGLAGDWLRAHVPPVDGVLCSTATRTRETLRNTRIAAPVRYSERLYASTPGTLIDEINTVDDGIGTLLVIGHEPTMSALALGLGRAGGTDAAAAERISAKFPTSAIAVLAVPCAWKELELGGASLIDFVVPR
>NC_016947.1|WP_009953979.1|1538705_1539857_+|exonuclease-SbcCD-subunit-D
MRFLHTADWQLGMTRHFLAGDAQPRYSAARRDAVAGLGALAAEVGAEFVVVSGDVFEHNQLPPTVIGQSLEAMRAIGIPVYLLPGNHDPLDASSVYTSALFAAERPDNVVVLDRAGVHQVRPGLEIVAAPWRSKVPTTDLVADVLDGLPAAAGTRILVAHGGVDVLDPDKDKPSLIRLATLDDALSRGAVHYVALGDKHSLTQVGDSGRVWYSGSPEVTNFDDVESDPGHVLVVDVDETDPRGAVSVTARDVGRWRFVTLHRQVDTSRDIADLDVNLDLMTGKDRTVVRLALTGSLTVTDCAALDACLDKYARLFAWLGLWERHTDLAVIPADGEFSDLGIGGFAAAAVEELVATAREEDSATAVDAQAALALLLRLADRGAA
>NC_016947.1|WP_014379578.1|1539853_1542475_+|AAA-family-ATPase
MKLHRLILTNYRGISHREIEFPDHGVVVVCGANEIGKSSMIEALDLLLESRDRSTKKEVKQVKPTHSDVGSEVSAEISCGPYRFVYRKRFHKKCETELTIITPCREQLTGDEAHERVRAMLAETVDSDLWHAQRVLQSASTAAVDLSGCDALSRALDVAAGDSGGLCGTEPLLIERIDTEYARYFTPTGRPTGQWAAAIARLADAEAAVAECAAAVAEVDDRVARHAVLTEQVADFSQRRIAAGPRVTAAREAADRIAELTAQQREAQLVAAAAAATSAAATAAHTGRLQLLAEIDARAAAVAETEAQAHQAASAHASARAEAEACDATLQRATQVLADLQCRVDAARRRVDRLADLEEADRLSTRLAKVDAIERDRERICAELSTIAVTEELLRRIEDACAAVDRIGDQLASTSAAIEFTAAADIHLVVGGERISLSAGQSWSITAAGSTVVEVSDVLTARVTPGATTLDIHTKHAAAQQEMAAALAAAEVADLAAARSADQRRRELVSARDQLGATLAGLCGDEQIDEMRSRLAQLRAQHPAEPAPGATDIGAARAELDAAQQGHAAASTDCEAHRQAATTAAAALAELSTRATVLQNTLEAQRAELQATAGRLAAERASVSDEELAASADSALRAAQAADQRVGELAAALAAASPDAVAAELAEATKEAESLRERYEEAARALREITIELSVFGSEGRQGKLDAAETEREHAATEHSQIGARARAAKLLRSVMTRHRDTTRRRYVEPYRAELQRLGRPVFGPSFEVDIDSDLCIRSRTLNGITVPYESLSGGAKEQLGILARLAGAALVAKEDAVPVVVDDALGFTDPDRLAKMGQLFDSVGTHGQVIVLTCSPDRYDGVRGAHRIDLTA

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Crispr_ID: NC_016947_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016947_4

3883384-3883472

Orphan

Consensus_repeat	Method
CCCGCCACGGCCGCGCTCGCGATCACCACTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_016947_4

>merge|NC_016947|4|3883384-3883472|CRISPRCasFinder
CCCGCCACGGCCGCGCTCGCGATCACCACTGGTGTCGATGAGTGGTGACCCGCTTCGCCCGGCACGGCCGCGCTCGCGATCACCACTGG

>NC_016947|4|4|3883384-3883472|CRISPRCasFinder
CCCGCCACGGCCGCGCTCGCGATCACCACTGG	TGTCGATGAGTGGTGACCCGCTTCG
CCCGGCACGGCCGCGCTCGCGATCACCACTGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_016947.1\|WP_014380734.1\|3889843_3890545_+\|IclR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224332
NC_016947.1\|WP_036390028.1\|3877021_3877951_-\|NADP-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|176191
NC_016947.1\|WP_009952786.1\|3894048_3895365_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341028
NC_016947.1\|WP_014383007.1\|3881436_3882480_-\|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|234629
NC_016947.1\|WP_026071268.1\|3891492_3892959_-\|glutamate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234953
NC_016947.1\|WP_008259004.1\|3885770_3886718_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239645
NC_016947.1\|WP_014383002.1\|3876180_3877011_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|180446
NC_016947.1\|WP_009952782.1\|3890595_3891108_+\|PPOX-class-F420-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274679
NC_016947.1\|WP_014383001.1\|3874933_3876178_+\|hypothetical-protein	unknown	unknown	unknown
NC_016947.1\|WP_008259010.1\|3888318_3889758_-\|3-isopropylmalate-dehydratase-large-subunit	unknown	unknown	gnl\|CDD\|235490
NC_016947.1\|WP_014383000.1\|3873750_3874941_+\|sulfotransferase	unknown	unknown	gnl\|CDD\|379204
NC_016947.1\|WP_008258983.1\|3877956_3878640_-\|uracil-DNA-glycosylase	unknown	unknown	gnl\|CDD\|235376
NC_016947.1\|WP_014383006.1\|3880259_3881405_-\|D-alanine--D-alanine-ligase	unknown	unknown	gnl\|CDD\|234993
NC_016947.1\|WP_014383008.1\|3882635_3883286_+\|2-phospho-L-lactate-guanylyltransferase	unknown	unknown	gnl\|CDD\|274643
NC_016947.1\|WP_009952784.1\|3892955_3893762_-\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NC_016947.1\|WP_008259006.1\|3886836_3887484_-\|HU-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|223847
NC_016947.1\|WP_014383005.1\|3879674_3880259_+\|DUF3515-domain-containing-protein	unknown	unknown	gnl\|CDD\|378794
NC_016947.1\|WP_009952778.1\|3883484_3885686_+\|RNA-degradosome-polyphosphate-kinase	unknown	unknown	gnl\|CDD\|235469
NC_016947.1\|WP_026071270.1\|3878681_3879629_-\|thiamine-phosphate-kinase	unknown	unknown	gnl\|CDD\|235583
NC_016947.1\|WP_008259008.1\|3887695_3888292_-\|3-isopropylmalate-dehydratase-small-subunit	unknown	unknown	gnl\|CDD\|179314

Protein	Function_ID	Function_description	E-value
NC_016947.1\|WP_014380734.1\|3889843_3890545_+\|IclR-family-transcriptional-regulator	gnl\|CDD\|224332	COG1414, IclR, Transcriptional regulator [Transcription].	9.97184e-54
NC_016947.1\|WP_036390028.1\|3877021_3877951_-\|NADP-dependent-oxidoreductase	gnl\|CDD\|176191	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases. Members identified as zinc-dependent alcohol dehydrogenases and quinone oxidoreductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	2.28815e-104
NC_016947.1\|WP_009952786.1\|3894048_3895365_+\|MFS-transporter	gnl\|CDD\|341028	cd17475, MFS_MT3072_like, Mycobacterium tuberculosis uncharacterized MFS-type transporter MT3072 and similar transporters of the Major Facilitator Superfamily. This family includes the Mycobacterium tuberculosis uncharacterized MFS-type transporter MT3072. It belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.80081e-92
NC_016947.1\|WP_014383007.1\|3881436_3882480_-\|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase	gnl\|CDD\|234629	PRK00094, gpsA, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.	1.46848e-163
NC_016947.1\|WP_026071268.1\|3891492_3892959_-\|glutamate--tRNA-ligase	gnl\|CDD\|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
NC_016947.1\|WP_008259004.1\|3885770_3886718_+\|NUDIX-hydrolase	gnl\|CDD\|239645	cd03673, Ap6A_hydrolase, Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most preferred substrate, hydrolyzes to produce two ATP molecules, which is a novel hydrolysis mode for Ap6A. These results indicate that Ap6A hydrolase is a diadenosine polyphosphate hydrolase. It requires the presence of a divalent cation, such as Mn2+, Mg2+, Zn2+, and Co2+, for activity. Members of the Nudix superfamily are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site.	3.72319e-48
NC_016947.1\|WP_014383002.1\|3876180_3877011_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|180446	PRK06180, PRK06180, short chain dehydrogenase; Provisional.	8.02002e-146
NC_016947.1\|WP_009952782.1\|3890595_3891108_+\|PPOX-class-F420-dependent-oxidoreductase	gnl\|CDD\|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	7.58746e-33
NC_016947.1\|WP_014383000.1\|3873750_3874941_+\|sulfotransferase	gnl\|CDD\|379204	pfam13469, Sulfotransfer_3, Sulfotransferase family.	2.81092e-33
NC_016947.1\|WP_008259010.1\|3888318_3889758_-\|3-isopropylmalate-dehydratase-large-subunit	gnl\|CDD\|235490	PRK05478, PRK05478, 3-isopropylmalate dehydratase large subunit.	0
NC_016947.1\|WP_008258983.1\|3877956_3878640_-\|uracil-DNA-glycosylase	gnl\|CDD\|235376	PRK05254, PRK05254, uracil-DNA glycosylase; Provisional.	6.84752e-129
NC_016947.1\|WP_014383006.1\|3880259_3881405_-\|D-alanine--D-alanine-ligase	gnl\|CDD\|234993	PRK01966, ddl, D-alanine--D-alanine ligase.	0
NC_016947.1\|WP_014383008.1\|3882635_3883286_+\|2-phospho-L-lactate-guanylyltransferase	gnl\|CDD\|274643	TIGR03552, F420_cofC, 2-phospho-L-lactate guanylyltransferase. Members of this protein family are the CofC enzyme of coenzyme F420 biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	9.52834e-57
NC_016947.1\|WP_009952784.1\|3892955_3893762_-\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	3.15919e-109
NC_016947.1\|WP_008259006.1\|3886836_3887484_-\|HU-family-DNA-binding-protein	gnl\|CDD\|223847	COG0776, HimA, Bacterial nucleoid DNA-binding protein [DNA replication, recombination, and repair].	2.20729e-24
NC_016947.1\|WP_014383005.1\|3879674_3880259_+\|DUF3515-domain-containing-protein	gnl\|CDD\|378794	pfam12028, DUF3515, Protein of unknown function (DUF3515). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 166 to 214 amino acids in length. This protein has a conserved RCG sequence motif.	2.14026e-55
NC_016947.1\|WP_009952778.1\|3883484_3885686_+\|RNA-degradosome-polyphosphate-kinase	gnl\|CDD\|235469	PRK05443, PRK05443, polyphosphate kinase; Provisional.	0
NC_016947.1\|WP_026071270.1\|3878681_3879629_-\|thiamine-phosphate-kinase	gnl\|CDD\|235583	PRK05731, PRK05731, thiamine monophosphate kinase; Provisional.	1.27195e-120
NC_016947.1\|WP_008259008.1\|3887695_3888292_-\|3-isopropylmalate-dehydratase-small-subunit	gnl\|CDD\|179314	PRK01641, leuD, 3-isopropylmalate dehydratase small subunit.	3.07167e-113

>NC_016947.1|WP_014383008.1|3882635_3883286_+|2-phospho-L-lactate-guanylyltransferase
MSGIRADGAGDVALIIAVKRLAAAKTRLAPVFSARTRESVVLAMLMDTLTAAGRVESLGSITVITPDDAAAAAAAELGADVLADPTPEGHPDPLNNAIATAARAVATSFSNVVALQGDLPALQTQELAEAVAAARQHRRSFVADRLATGTAALFAFGGPLDPRFGSDSSARHRSSGAIELTGAWPGLRCDVDTPTDLAAARRLGVGAATARAIAAH
>NC_016947.1|WP_014383007.1|3881436_3882480_-|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase
MTSTHAGSTGAVTVMGAGAWGTALAKVLVEAGGPETQVTLWARRPELAERINATRSNPDYLPGTSLPPGIRATADAAEALQNASTVLLGVPAQTMRSNLERWTPLLREGATLVSLAKGIELGTLMRMSQVIVAVTGVDPAHVAVISGPNLASEIAGCQPAATVVACGDSGRAVALQRMLNSGYFRPYTNSDVVGTEIGGACKNVIALACGMAAGVGLGENTAAAIITRGLAEIMRLGIALGAKGATLAGLAGVGDLVATCSSPHSRNRSFGERLGRGATVESILSGTPDGGDGHVVEGVTSCESVLALAASYDVEMPLTDAVHRVCHKGLSVDEAMALLLGRRTKPE
>NC_016947.1|WP_014383006.1|3880259_3881405_-|D-alanine--D-alanine-ligase
MNASDRSTPHPGSGGGERARVAVVFGGRSNEHAISCVSAGSILRNLDPERFEVVAIGITPEGSWVLTDGDPAALAITDRRLPEVTAESGTELALPADPRRGGQLVALPPGAGEVLASVDVVFPVLHGPYGEDGTIQGLLELAGVPYVGAGVLASAAGMDKEFTKKLFAAEGLPVGDYAVLRPSRARLRPEECQRLGLPVFVKPARGGSSIGVSRVASWDQLDAAVAAARRHDPKVIVEAAIVGRELECGVLEMPDGTVEASALGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDEIADTVRQLAIRAFRAIDCQGLARVDFFLTEDGPVLNEINTMPGFTTISMYPRMWAASGVDYPTLLATMVETALARGVGLR
>NC_016947.1|WP_014383005.1|3879674_3880259_+|DUF3515-domain-containing-protein
MWGQEVRAVATESDADGGPPRAVIIVAVALAITTIGVILAIAATREAPPQPVAVAGVPAPQADSPACRALMDALPQRLGDYQRAALEQPEPVGAAAWRSGRGADPVVLRCGLDRPGEFVVGSPIQVVDRVQWFQVRSDQQSAGDAGRSTWYAVDRGVYVALTLPTGSGPAPIQRLSEVIAQRIPAGPISPGPAR
>NC_016947.1|WP_026071270.1|3878681_3879629_-|thiamine-phosphate-kinase
MRDESTLRQLGEFAVIDRLVAGRRQPAAVVLGPGDDAALVAAGDGRTVVSTDMLVQDRHFRLDWSTPHDIGRKAIAQNAADIEAMGARPTAFVVAFGAPGETPAASVDALVDGMWDEAQRVGAGIAGGDLVSCPQWVISVTVLGDLGGREPVRRSGATPGSLVAVAGDLGRSAAGFALWHTGIGGFEELRRRHVVPEPPYGQGAVAAAGGAQAMIDVSDGLIADLRHVADASGVGIDLSTAALAADRDALAAAAAAAGADPWPWVLGGGEDHALVACFAGPAPAGWRIIGRVLDGPARVLVDDQEWSGHAGWQSY
>NC_016947.1|WP_008258983.1|3877956_3878640_-|uracil-DNA-glycosylase
MTARPLSELVEPGWANALQPVAGQVAQMGQFLRDEIAAGRRYLPAGPNVLRAFTYPFDQVRVLIVGQDPYPTPGHAVGLSFSVAPEVRPLPRSLANIFQEYTTDLGHPPPSCGDLTPWAQRGVLLLNRVLTVRPSNPASHRGKGWEAVTECAIRALTARSLPLVAILWGRDASTLKPILAQGNCVAIESPHPSPLSASRGFFGSRPFSRANELLAGMGADAIDWRLP
>NC_016947.1|WP_036390028.1|3877021_3877951_-|NADP-dependent-oxidoreductase
MTALRANRRGGPEQLVIERAPVPVAAAGEALVAVHAAAITFDELTWEETWTRDGVSRTPVIPSHEVSGVVSAVADDVTDFVPGDEVYGLIAFDRDGAAADFVAVPAADLAAKPSTVSHVVAAALPLAGLTALQALVDHAAVRPKESVLVHGGAGGVGLLTVQLAALLGAQVTATVRSDTANLLRGCGAQRVIDTRTEAFDEAGAAYDVVVDTVGGQTLERSYGVLRRGGRLVTLSAPPPDGRADEFGVSATFFIVTPNRDQLAELAALVDSDRLHVAIAQTFPLDEGREAFESRERGGRAGKTVLVVRD
>NC_016947.1|WP_014383002.1|3876180_3877011_+|SDR-family-NAD(P)-dependent-oxidoreductase
MARWLITGCSTGFGREIARAALEAGHSVVVTARRAEAVRDLADEFGDRALAVALDVTDTGQVAAAVAAADEAFGGIDVLVNNAGHGYLSAVEEGEDAEVRKLFDVNYFGAVDMIKAVLPAMRARGSGHIINISSMTGLVANPPNAYYSSTKFALEAVTEALATEVRPLGIKVTAVEPGAFRTDWATRSMKESGAPITDYADVAARKDLIKQFADHLPGDPRKVAEAVLMLARLDDPPLRLLLGRDVLKAMRDKIAALSASIDEWEAVTKDVNFPAS
>NC_016947.1|WP_014383001.1|3874933_3876178_+|hypothetical-protein
MPEDPVATASQHEQELAALELIEHPTVKAAYRTVAETWLGRAKASDAMRERFDDAFAEVMFSAAMWSSNQDKLRPKVSCITRLAHPVNGRRIPGSRWGIDNPDSVYRVIPISGDERYEIHGRVGEHRMTENYFTLWDANMGTVDVLNGRTMRVDSDGSFTITVDSEPANGRPNHVRSTPAAHEFYIRDVLLDWGRDDPNHLEVQRLGAPASTPARTLDEQAEATAAMMDYFANFTGKLSHGVYKMPANQFNLAWSADKIGAMRNQVYVMGRLDLGPDEAFVVDLNDGGAEYFTVPLSNVWGTTLELVDRTGSLNKAQSVPNQDGTYTYVISPVDPGVANWIDSDGLREAILTLRMAEFGENGPREDLGARGRVVKLDRLDAEVGHLERVSPQQRAAQLAERRKGYLRRLPEGTI
>NC_016947.1|WP_014383000.1|3873750_3874941_+|sulfotransferase
MPSPSVFEPAAVLADARRKEGLTDWGPGEFEEPLTVLLRDYARADLNAIGTHILRSGIVHSLRMRLRTQEWIRRHPEILDERVAAPIVVVGMMRSGTTLLQRLLAADPRFVCAYGWEVVEVAPRLNHPFTGVDPRIAISQAREAKSRELAPELFSIHPMYATEAEEEIVFLADAFLSHVPESGAHLPHYRTWLDDQDFTPAYAYLHRMLQFLQWQKRQRGQAGQRWVLKSPAHLGYLGLLRAHFPDLHVVHMHRDPRTTIASGASLNATLHAMHADVVDTHRVGAQWLARMGWTNDRAMTTRDGWSDDGERVTDIGFDDAVADPIGQVARVYDAIGLPLTAEAEDAMRRWLRERPREAARPPYGLENYGLLPEQVDERFTLYNKRFAQYIGGTAHA
>NC_016947.1|WP_009952778.1|3883484_3885686_+|RNA-degradosome-polyphosphate-kinase
MMSDDRRVTEIEAEARPDENLWHSGDSAVAAPPAATPTAMTDLPDERYLNRELSWLDFNARVLALADDNSLPLLERAKFLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLTPRKQLALIGEQTQRIATRHARVFLDSVRPALAEEGIHIVTWADLDQAERDELSAYFTEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVMVRQPEDGGQHFARVKVPNNVDRFVELAAPRSGRDSAAGEARSIVRYLPLEELIAAFLPLLFPGMEIVEHHAFRITRNADMEVEEDRDEDLLQALERELARRRFGPPVRLEIADDMTEGMLELLLRELDVHPGDVIEVPGLLDLSSLWQIYDLDRPALKDPAFVPDTHPAFADRESPKSIFATLREGDVLVHHPYDSFSTSVQRFIQQAAADPNVLAIKQTLYRTSGDSPIVRALIEAAEAGKQAVALVEIKARFDEQANIRWARALEQAGVHVVYGLVGLKTHCKTCLVVRREGSAIRRYCHIGTGNYNSKTARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKVSYRNLLVAPHGIRTGIIERVEREIAAHRERGDGRIRLKMNALVDEQVIDALYRASQAGVRVEVVVRGICALRPGAQGYSENIVVRSILGRFLEHSRIIHFRNINEFWIGSADMMHRNLDRRVEVLAQVKDPKLTAQLDELFESALDPSTRCWELGSDGQWTASPQEGHTVRDHQVSLMERHRSP
>NC_016947.1|WP_008259004.1|3885770_3886718_+|NUDIX-hydrolase
MPPSSSSSARRSGSRIVHAAGAVLWRPGDADTADHDVEIAVIHRPRYDDWSLPKGKVDPGETAPVAAVREVYEETGQHAVLGRRLNAVSYPIDAGVKKVSYWSARAVGGEFVPGDEVDRLLWLPAAEAMRKLDYAQDRKVLRHFNKKPADTHTVLVVRHATAGRKSRFSGDDTKRPLDKRGRAQAKALVPQLLAFGASRVYAADRVRCHQTVEPLAEELGSTVHNEPTLTEEAYAKNAKRGRHRMLDIAGEHGTPVVCTQGKVIPDLIAWWCARDGVRPDKSRNHKGSTWVLSLSGGRLVAADHLGGALAANVRA
>NC_016947.1|WP_008259006.1|3886836_3887484_-|HU-family-DNA-binding-protein
MNKAELIDVLTQKLNTDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFRPGAQFKAVVSGAQRLPSDGPAVKRGVVGGTGAAKKTAAKKAPAKKAAAKKAPAKKAAAKKAPAKKAAVKKAPAKKAAVKKAPARKAATKAPAKKTAAKKAPARKAATKAPAKKAASKSTARKAPAKKTTARRGRR
>NC_016947.1|WP_008259008.1|3887695_3888292_-|3-isopropylmalate-dehydratase-small-subunit
MEAFHTHTGIGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFASWRSDPSFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDIFRGNAGKAGLLAAEVSQDGVELLWKLIEQSPGLEITANLQDRNITAGTTVLPFKIDDHTAWRLLEGLDDIALTLRKLDEIESFEAAYPDWKPRTLSTS
>NC_016947.1|WP_008259010.1|3888318_3889758_-|3-isopropylmalate-dehydratase-large-subunit
MGSDAGAAAKPRTLAEKVWDDHVVVSGGASGQGAPDLIYIDLHLVHEVTSPQAFDGLRLAGRPVRRPDLTLATEDHNVPTIDIDKPIADPVSRTQVETLRRNCAEFGVRLYPMGNLEQGIVHVVGPQLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMAVNVDGKLPPGVTAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTVCNMSIEAGARAGMVAPDATTYEFLCDRPHAPKGAQWDAAMRYWQQLHTDPGAEFDTEVYLDAESLSPFVTWGTNPGQGVPLAAAVPDPELMADDGERQAAEKALAYMDLRPGTPMRDIAVDAVFVGSCTNGRIEDLRAVADILRGRKIAPGVRMLVVPGSMRVRAQAEDEGLGEVFTAAGAEWRQAGCSMCLGMNPDQLAPGERCAATSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSAPADLS
>NC_016947.1|WP_014380734.1|3889843_3890545_+|IclR-family-transcriptional-regulator
MRQHSGIGVLDKAVGVLHSVAQSPCGLAELCERTGLPRATAYRLAAALEVHRLLARDDEGRWRLGPAVTELAAHVNDPLLAASSAVLPLLRETTGESVQLYRREGTDRVCVAALEPAAGLRDTVPVGARLPMTAGSGAKVLLAHSDAATQKAVLATAKFTERTLAEVRRRGWAQSVAEREPGVASVSAPVRDGRGTVVAAISVSGPIDRIGRRPGARWAADLLSAADAMARRL
>NC_016947.1|WP_009952782.1|3890595_3891108_+|PPOX-class-F420-dependent-oxidoreductase
MGTNQRASIVMSEDEIADFVVKSRTGTLATVGPDGQPHLTAMWYAVVDGEIWLETKAKSQKAVNLKRDPRVSFLIEDGHTYDTLRGVSFEGVAEIVDDPDVSHRVGVSVWERYTGPYTEDMKPFVEQMMNKRVCVRIVARRARSWDHRKLGLAPMPVGGSTAPAVLGNDQ
>NC_016947.1|WP_026071268.1|3891492_3892959_-|glutamate--tRNA-ligase
MTAPANVRVRFCPSPTGTPHVGMVRTALFNWAYARHTGGTFVFRIEDTDAQRDSEESYLALLDALRWLGLDWDEGPEVGGPYGPYRQSLRGEIYRDVVAKLVEAGEAYYAFSTPEEVEARHLAAGRNPKLGYDNFDRQLTDSQRAAFLAEGRQPVVRLRMPDGDLSWDDLVRGTTTFAAGSVPDFALTRANGDPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALYQALIRIGVAERTPQFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWAIADDHDVFSLDEMVAAFDVVDVNSNPARFDQKKADALNAEHIRMLTVEDFTARLRDYFGVHGHRLELDDAGFATAADLVQTRIVVLGDAWDLLKFLNDDEYAIDPKAAAKELGPDSATVLDAALGALDGVADWTTPQIEAALKAALIDELGLKPRKAFGPIRVGATGTTVSPPLFESLELLGRDRSVRRLRAARATIG
>NC_016947.1|WP_009952784.1|3892955_3893762_-|fumarylacetoacetate-hydrolase-family-protein
MRLGRIASPDGVAFVSIEGELDDPAEMIAREIAEHPFGTPNFTGRSWPLADVRLLAPILASKVVCVGKNYTDHIAEMKDMTGPAPAEPVIFLKPNTAIIGPNVPIRLPANASPVHFEGELAVVIGRPCKDVSAAQAADNILGYTIGNDVSARDQQKADGQWTRAKGHDTFCPVGPWIVTDLKPLDPGDLELRTEVNGEVKQHSRTSLLIHDIGSIVEWISAVMTLLPGDIILTGTPAGVGPIEDGDTVSITIEGIGTLTNPVLRKGKS
>NC_016947.1|WP_009952786.1|3894048_3895365_+|MFS-transporter
MQTDSTDTPEIGAGVRWSIMVVSLLATASSFLFINGVAFLIPSLRVRGVRLDEAALLASMPSWGMVVTLVLWGYVLDRVGERVVMATGSALTAAAAYAAASAHSLVLMSVYLFLGGMAAASCNTAGGRLVSAWFPPQQRGLAMGIRQTAQPLGIALGAMVIPELAEHGPQHGLRFAALACAVGAIASVIGIVDPPRKPRASASHQELASPYRKSLTLWRIHAVAGLMMMPQTVTVTFMLVWLIRNLHWSVTAAGGLVTLSQLLGALGRVAVGRLSDRVGSRMRPVRYIAAVAVLALLLLAWADYMNSRWQAGLMVVIAVISVLDNGLEATAITEFAGPYWSGRALGIQNTTQRMMAAAGPPLFGALIAAAKYPPAWLLCALFPLAAVPLVPTRLLPPGLETRARRQTVRRVRWWRAIRSHAMPNRPERRLPQRSGENY

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Crispr_ID: NC_016947_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016947_5

4159202-4159308

Orphan

Consensus_repeat	Method
CCGCCGCGCCCGGCTCCGCCGCGCTTGCGATCGCCAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_016947_5

>merge|NC_016947|5|4159202-4159308|CRISPRCasFinder
CCGCCGCGCCCGGCTCCGCCGCGCTTGCGATCGCCACCGGCTCACGCGCGGCGACCCGCCGCGCCCGGCTCCGCCGCGCCCGGCTCCGCCGCGCTTGCGATCGCCAC

>NC_016947|5|5|4159202-4159308|CRISPRCasFinder
CCGCCGCGCCCGGCTCCGCCGCGCTTGCGATCGCCAC	CGGCTCACGCGCGGCGACCCGCCGCGCCCGGCT
CCGCCGCGCCCGGCTCCGCCGCGCTTGCGATCGCCAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_016947.1\|WP_014383122.1\|4158149_4159166_+\|sensor-domain-containing-protein	unknown	unknown	gnl\|CDD\|372884
NC_016947.1\|WP_009956825.1\|4156694_4157354_-\|UdgX-family-uracil-DNA-binding-protein	unknown	unknown	gnl\|CDD\|274850
NC_016947.1\|WP_009954052.1\|4168852_4169389_-\|DUF1360-domain-containing-protein	unknown	unknown	gnl\|CDD\|369207
NC_016947.1\|WP_009954046.1\|4163028_4165188_-\|glycogen-debranching-protein-GlgX	unknown	unknown	gnl\|CDD\|131155
NC_016947.1\|WP_008259541.1\|4160288_4161056_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NC_016947.1\|WP_014383120.1\|4151938_4152199_-\|pH-regulation-protein-F	unknown	unknown	gnl\|CDD\|237148
NC_016947.1\|WP_014380870.1\|4157422_4157980_-\|hemerythrin-domain-containing-protein	unknown	unknown	gnl\|CDD\|376622
NC_016947.1\|WP_014380868.1\|4152195_4152735_-\|Na+/H+-antiporter-subunit-E	unknown	unknown	gnl\|CDD\|376653
NC_016947.1\|WP_014383119.1\|4151298_4151598_-\|DUF4040-domain-containing-protein	unknown	unknown	gnl\|CDD\|183561
NC_016947.1\|WP_008259529.1\|4153059_4153458_+\|hemophore-related-protein	unknown	unknown	gnl\|CDD\|374603
NC_016947.1\|WP_136245179.1\|4151594_4151942_-\|Na+/H+-antiporter-subunit-G	unknown	unknown	gnl\|CDD\|237169
NC_016947.1\|WP_009956826.1\|4154878_4156672_+\|thiamine-pyrophosphate-requiring-protein	unknown	unknown	gnl\|CDD\|181344
NC_016947.1\|WP_014380875.1\|4169977_4170427_+\|Hsp20-family-protein	unknown	unknown	gnl\|CDD\|365807
NC_016947.1\|WP_014383123.1\|4159320_4160292_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381319
NC_016947.1\|WP_026071237.1\|4166522_4167230_-\|GAF-and-ANTAR-domain-containing-protein	unknown	unknown	gnl\|CDD\|198080
NC_016947.1\|WP_009954047.1\|4165281_4166463_-\|glutathione-dependent-formaldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|176243
NC_016947.1\|WP_009954053.1\|4169453_4169834_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133394
NC_016947.1\|WP_014380872.1\|4161148_4162942_-\|sensor-domain-containing-diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635
NC_016947.1\|WP_036389990.1\|4153599_4154655_+\|DNA-topoisomerase-IB	unknown	unknown	gnl\|CDD\|226099
NC_016947.1\|WP_009954051.1\|4167538_4168849_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172

Protein	Function_ID	Function_description	E-value
NC_016947.1\|WP_014383122.1\|4158149_4159166_+\|sensor-domain-containing-protein	gnl\|CDD\|372884	pfam14032, PknH_C, PknH-like extracellular domain. This domain is functionally uncharacterized. It is found as the periplasmic domain of the bacterial protein kinase PknH. The domain is also found in isolation in numerous proteins, for example the lipoproteins lpqQ, lprH, lppH and lpqA from M. tuberculosis. This family of proteins is found in bacteria. Proteins in this family are typically between 214 and 268 amino acids in length. There are two completely conserved C residues that are likely to form a disulphide bond. A second pair of cysteines are less well conserved probably form a second disulphide bond. It seems likely that this domain functions to bind some as yet unknown ligand.	1.80941e-28
NC_016947.1\|WP_009956825.1\|4156694_4157354_-\|UdgX-family-uracil-DNA-binding-protein	gnl\|CDD\|274850	TIGR03914, SPO1_DNA_polymerase-related_protein, uracil-DNA glycosylase family domain. This model represents a clade within the uracil-DNA glycosylase superfamily. Among characterized proteins, it most closely resembles the Thermus thermophilus uracil-DNA glycosylase TTUDGA, which acts uracil (deamidated cytosine) in both single-stranded DNA and U/G pairs of double-stranded DNA. This domain may occur either as a stand-alone protein or as the C-terminal domain of a fusion with another domain that always pairs with a particular radical-SAM family protein.	9.27576e-81
NC_016947.1\|WP_009954052.1\|4168852_4169389_-\|DUF1360-domain-containing-protein	gnl\|CDD\|369207	pfam07098, DUF1360, Protein of unknown function (DUF1360). This family consists of several bacterial proteins of around 115 residues in length. Members of this family are found in Bacillus species and Streptomyces coelicolor, the function of the family is unknown.	1.64246e-47
NC_016947.1\|WP_009954046.1\|4163028_4165188_-\|glycogen-debranching-protein-GlgX	gnl\|CDD\|131155	TIGR02100, Glycogen_operon_protein_GlgX_homolog, glycogen debranching enzyme GlgX. This family consists of the GlgX protein from the E. coli glycogen operon and probable equivalogs from other prokaryotic species. GlgX is not required for glycogen biosynthesis, but instead acts as a debranching enzyme for glycogen catabolism. This model distinguishes GlgX from pullanases and other related proteins that also operate on alpha-1,6-glycosidic linkages. In the wide band between the trusted and noise cutoffs are functionally similar enzymes, mostly from plants, that act similarly but usually are termed isoamylase. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NC_016947.1\|WP_008259541.1\|4160288_4161056_-\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	9.32196e-36
NC_016947.1\|WP_014383120.1\|4151938_4152199_-\|pH-regulation-protein-F	gnl\|CDD\|237148	PRK12599, PRK12599, putative monovalent cation/H+ antiporter subunit F; Reviewed.	2.49583e-11
NC_016947.1\|WP_014380870.1\|4157422_4157980_-\|hemerythrin-domain-containing-protein	gnl\|CDD\|376622	pfam01814, Hemerythrin, Hemerythrin HHE cation binding domain. Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor hemerythrin binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial NorA is a regulator of response to NO, which suggests yet another set-up for its metal ligands. In Staphylococcus aureus the iron-sulfur cluster repair protein ScdA has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger.	9.641e-08
NC_016947.1\|WP_014380868.1\|4152195_4152735_-\|Na+/H+-antiporter-subunit-E	gnl\|CDD\|376653	pfam01899, MNHE, Na+/H+ ion antiporter subunit. Subunit of a Na+/H+ Prokaryotic antiporter complex.	6.13111e-22
NC_016947.1\|WP_014383119.1\|4151298_4151598_-\|DUF4040-domain-containing-protein	gnl\|CDD\|183561	PRK12504, PRK12504, DUF4040 domain-containing protein.	5.44468e-09
NC_016947.1\|WP_008259529.1\|4153059_4153458_+\|hemophore-related-protein	gnl\|CDD\|374603	pfam16525, MHB, Haemophore, haem-binding. MHB is a coiled-coil molecule that binds free haem in mycobacterial cytoplasm to deliver it to membrane proteins for shuttling through the membrane.	1.78804e-32
NC_016947.1\|WP_136245179.1\|4151594_4151942_-\|Na+/H+-antiporter-subunit-G	gnl\|CDD\|237169	PRK12674, PRK12674, putative monovalent cation/H+ antiporter subunit G; Reviewed.	2.49087e-22
NC_016947.1\|WP_009956826.1\|4154878_4156672_+\|thiamine-pyrophosphate-requiring-protein	gnl\|CDD\|181344	PRK08273, PRK08273, thiamine pyrophosphate protein; Provisional.	0
NC_016947.1\|WP_014380875.1\|4169977_4170427_+\|Hsp20-family-protein	gnl\|CDD\|365807	pfam00011, HSP20, Hsp20/alpha crystallin family. Not only do small heat-shock-proteins occur in eukaryotes and prokaryotes but they have also now been shown to occur in cyanobacterial phages as well as their bacterial hosts.	1.27423e-26
NC_016947.1\|WP_014383123.1\|4159320_4160292_+\|aldo/keto-reductase	gnl\|CDD\|381319	cd19093, AKR_AtPLR-like, Arabidopsis thaliana pyridoxal reductase (PLR) and similar proteins. Arabidopsis thaliana PLR (EC 1.1.1.65) is the prototype of this family. It catalyzes the reduction of pyridoxal (PL) with NADPH and oxidation of pyridoxine (PN) with NADP(+), and is involved in the PLP salvage pathway.	7.13798e-109
NC_016947.1\|WP_026071237.1\|4166522_4167230_-\|GAF-and-ANTAR-domain-containing-protein	gnl\|CDD\|198080	smart01012, ANTAR, ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins. The majority of the domain consists of a coiled-coil.	4.93016e-16
NC_016947.1\|WP_009954047.1\|4165281_4166463_-\|glutathione-dependent-formaldehyde-dehydrogenase	gnl\|CDD\|176243	cd08283, FDH_like_1, Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1. Members identified as glutathione-dependent formaldehyde dehydrogenase(FDH), a member of the zinc-dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. MDH family uses NAD(H) as a cofactor in the interconversion of alcohols and aldehydes, or ketones. Like many zinc-dependent alcohol dehydrogenases (ADH) of the medium chain alcohol dehydrogenase/reductase family (MDR), these FDHs form dimers, with 4 zinc ions per dimer. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit.	0
NC_016947.1\|WP_009954053.1\|4169453_4169834_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|133394	cd04766, HTH_HspR, Helix-Turn-Helix DNA binding domain of the HspR transcription regulator. Helix-turn-helix (HTH) transcription regulator HspR, N-terminal domain. Heat shock protein regulators (HspR) have been shown to regulate expression of specific regulons in response to high temperature or high osmolarity in Streptomyces and Helicobacter, respectively. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	4.87249e-34
NC_016947.1\|WP_014380872.1\|4161148_4162942_-\|sensor-domain-containing-diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.81795e-52
NC_016947.1\|WP_036389990.1\|4153599_4154655_+\|DNA-topoisomerase-IB	gnl\|CDD\|226099	COG3569, COG3569, Topoisomerase IB [DNA replication, recombination, and repair].	1.54978e-65
NC_016947.1\|WP_009954051.1\|4167538_4168849_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	9.36796e-99

>NC_016947.1|WP_014383122.1|4158149_4159166_+|sensor-domain-containing-protein
MTNPQDPYWQNPLSYDPLGRVPPIEPMEPIEPPAEPPGIPPPPAPPPYRPAVNTLATLSLVFAFVFAPAGAVLGHLGLARIRRTGELGRDRALVGVTLSYVFILLAVVALAGWATLGGSTSSHRTAHDATTSAGPPPPTVPPDTITTLLPGLDALRNITSDANLEVGPTWNSPGRSAQDGSIDRPECWGSIAAGSPDAYTPGSFTGYHAGEFTDTRSMFKSIQVIQGVAAFRDPAGAQSQLDTLLSGWRQCGGSTVTVTASGGQPIKMAVSAPADAGNGITTLDLTPKGIQVRSARAVAAKANVVLDLNVSASGTTDSERPRLAAVTIANYILGKIPG
>NC_016947.1|WP_014380870.1|4157422_4157980_-|hemerythrin-domain-containing-protein
MARAITSPTDVVDFLVSQHEQIKAMFADTLAASGEAREKAFVELRRLLAVHETAEEEIVHPRAKRKIANGTTVVDKRLHEEHEAKTVLQRLEKLDVDSEEFTRELTKLRDAVIDHAEHEEHDEFAKLGEELSADELERMGRAAQLAEAIAPTRPHAGVESQVANLAAGPFAAMLDRARDAIVGKG
>NC_016947.1|WP_009956825.1|4156694_4157354_-|UdgX-family-uracil-DNA-binding-protein
MTATAKAPGADRYLPEERDIDALRSAAETCHGCALFEDATQTVFGNGHPGAPIMLVGEQPGDQEDRAGEPFVGPAGRLLARALEDAGIDPVLTYQTNAVKHFKFTRKGGKRRIHQKPGRTEVVACRPWLIAEIEAVQPEVIVCLGATAAQSLLGTTFRVSEQRGRELKLPESVDIARTPEPIVVATVHPSSVLRDRSDRRDEVYQSFVDDLRIARSGLA
>NC_016947.1|WP_009956826.1|4154878_4156672_+|thiamine-pyrophosphate-requiring-protein
MSKQEVSDYLLERLRAWGVEHVFGYPGDGINGLLAAWGRADNKPQFIQSRHEEMSAFEAVGYAKFTGRVGVCAATSGPGAVHLLNGLYDAKLDHVPVVAIVGQTNRSAMGGNYQQEVDLLNLFKDVASDYVQMVTVPEQLPNVLDRAIRIAMTQRAPTALIIPSDVQELPYSPPEHAFKMVPSSLGIEYPDIAPDDAAIARAADVLNAGKKVAMLVGTGARGAHEELAEVADLLGAGAAKALLGKDVLSDELPWVTGSIGLLGTRPSYELMMGCDTLLTVGSSFPYTQFLPQFDQCRAVQIDIDGRMIGMRYPYEVNLVADAKSALRALIPHLRRKEDRSWREGVEKNVARWWETMDKEAMVSADPINPMRLFSELSPQLPENAIVTADSGSSANWYARNLRFRGNMRGSLSGTLATMGPGVPYGIGAKFGHPDRPVIVFAGDGAMQMNGMAELITIKRYWSEWKDPRLIIAILHNNDLNQVTWEMRAMAGAPKFAESQNLPDVDFAAFAASLGLNAMAIKDPDELSDAWRNALSADRPTVLDVFTDPDMPPIPPHATWEQFKSATTAVLSGDEDRVGFVKVGLKTKMQEFMPHKKS
>NC_016947.1|WP_036389990.1|4153599_4154655_+|DNA-topoisomerase-IB
MRLRRSVLSKPGIARKRRGKGFSYYEPGGKPVSDPETLQRIKDLVIPPAWKKVWISPHPNGHIQAVGVDAAGRRQYLYHSAWQAERAEEKFDRVLELSTRLPACRAQIAKDLARHGLTRKRVLALALRLLDRGYFRAGGEQYAEEHESYGLSTLLCEHVVVRRDAVEFDFPAKSGVRRTVEIEDPDVVRAVRALMRRPDRTERLLVCRNSSGWIDVRADDLNARFKELAGDDYTVKDLRTWHGTVLAAAAFADADPAVSGRVAKRVEAAVMKEVAEELGNTPAVARGSYVDPRVVTGYEQGLTIAAAARRAERAKSPDLAQEILDKATRMLIRRVAKADSANGSSGLRKTA
>NC_016947.1|WP_008259529.1|4153059_4153458_+|hemophore-related-protein
MKISSIVARRRVAGVSAGCLLGGMAMGIVGAPSAAAAPDCSPAGVNSTVSSVQGSAEQYLAAHPGANQVVTAAYGQPRPEAASSLRSYFTGHPQEYYDLRGILAPIGETERQCNVTALPPYLESAYHEFMAG
>NC_016947.1|WP_014380868.1|4152195_4152735_-|Na+/H+-antiporter-subunit-E
MGIGVGIAARAQRVVALTAWAFAVWILLTWTPTVENLLVGLVVAVGCGFAFAPLGPVAGPWSALAPRRLAALVALAAACAARIVAANLSLSRRILSPSRPLRSGMIIAPTQARSDGELAATGLLTSLVVDNQFVDLDRGRHLLQYHAMAVPRGPARESVNGPLESRVIAVSRSRGGTSG
>NC_016947.1|WP_014383120.1|4151938_4152199_-|pH-regulation-protein-F
MSGVLSGVCIAQLLVACVLLIRLARGPSVSDRVVALNTISTQCALVVLFYAAVADRAIYLDVALWLASFSYLGALVWARYLERGLL
>NC_016947.1|WP_136245179.1|4151594_4151942_-|Na+/H+-antiporter-subunit-G
MSSVVIDALVIVLCVVGVFFSLSGAIGILRMPDVYTRIQCSSKTITAGALPLLAGLAVAKGPFTEYGSRALLVAVLLLLVNPIAAHALARAAYKTGVPMWHGAVIDQPEGPGAGR
>NC_016947.1|WP_014383119.1|4151298_4151598_-|DUF4040-domain-containing-protein
MTSLWAVDYLCLALVVGCAVLVVFLRSITGSVMALSAMGTVLGALFVVMAAPDVALATVAVGAIAQPVLYLIAIGKIRTDVFDRGELGEALDDGGARDD
>NC_016947.1|WP_014383123.1|4159320_4160292_+|aldo/keto-reductase
MKYVDVDGVGRVSRIGLGTWQFGSREWGYGDSYAAGAAGDIVRRARALGVTLFDTAEVYGLGKSERILGEALGDERAEVAVASKIMPVAPFPAVVRQRARASARRLGLDRIPLYQIHQPNPVVPDSVIMPGMRDLLDRGTIGAAGVSNYSLQRWQKADTALGGPVISNQVHFSLAYPKALKNLVPFAERENRIVIAYSPLEQGLLGGKYGVDNRPGGVRAMNSLFGTENLRRVEPLLQLLRDVATQLGAKPAQVALAWLISYPGVVAIPGASSVEQLEFNVAAADIELPTESRDALTEAALAFRPTSAARFLTDLAREKLGRR
>NC_016947.1|WP_008259541.1|4160288_4161056_-|SDR-family-oxidoreductase
MVVGASSGLGRCIGVGLAQRGDQVALLARRLQRIEAAAKEAGPNATAIECDVTDEASCRAAIGRAVDALGGIDNLVYTPAVGPLVRMVDTDADTWRRIFDTNVIGASLVTAAAMPHLTASAGKAVYLSSDAGTFGPPWPGLGAYGVSKAALERLVEAWRAEHSDVGFTNLIVGECAGGEGDAATGMNADWDMDLAMKAVPLWSSRGCMPGKLMPVDDLIDVVHTILRTNASTSMPLVVARGAPASPAAFAEANQS
>NC_016947.1|WP_014380872.1|4161148_4162942_-|sensor-domain-containing-diguanylate-cyclase
MLRAERREREGQPMDRPGPDARLESAMNTSGRAAALLVLVVAALTWVGWTAGIERLTRIYPTWPQMMPWTALWLAALGAAILLQWGSPSRERRWAGRCLAAAAAAFAVLVLAEYASLGSFTVDRIWFGEAVGMREWSWPGRPSVQTALSALPLATAVALIRVDRCTRAVWPLCLAASAAIPFVTAGAYLFDALALVGVSPSKGQAFLTAAALLLLVAATSLARVDRFPLAWLLARPDRSSLVRLLAILAGFPLVVAVVRPIFLELGPDANAQWTFSILLGTAVVGAVTFYFSQREQHLLIAKELASKQRAEAETRYRILADNAVDIIVHFRGGGVAWISPSVEPALGGPLSRWTGTDFARRIHPEDRDKLQTALRRIAGGEQVLQRFRVCSLDGEYHWVDGHGKPYTDAQGNTDGLIAALRVVDDQVEAEQQLERLARFDTLTGLVNRAEALARLDAALRQPRPPETHVGVLFCDVDHFKAINDRWGHGTGDVVLATVAARIRASVRREDTVGRTGGDEMLILLPGVRSADELAQIAEKIRRRVAEPIHVSGNTIGATLSIGATLALPAESVDAVTARADEAMYRAKSGDRNAVVAT
>NC_016947.1|WP_009954046.1|4163028_4165188_-|glycogen-debranching-protein-GlgX
MTPAEAADAGAPTPTGEVWPGRAYPLGATYDGAGTNFALFSEVAERVELCLFDAEGTESRITLPEVDGFIWHAYIPNIEPGQRYGYRVHGPYDPQAGHRCNPNKLLVDPYSKAIDGSFEWNQSLFSYNFGDPDSRNDDDSAASMPKSVVISPYFDWGNDRPPDRHYADTVIYEAHVKGLTQTHPDIPEQLRGTYAAVAHPVIIDHLKDLGITAIELMPVHHFANDSTLVDKGLSNYWGYNTIGFFAPDFKYSSATTPGGQVQEFKAMVRSLHEAGIEVILDVVYNHTAEGNHLGPTLSMRGIDNAAYYRLVDDDKQYYMDYTGTGNSLNVGHPHALQLIMDSLRYWVTEMHVDGFRFDLASTLAREFYDVDRLSTFFELVQQDPTVSQVKLIAEPWDVGPGGYQVGNFPPQWTEWNGKYRDTVRDFWRGEPATLDEFAYRLSGSADLYEHTARRPVASINFVIAHDGFTLRDLVSYNEKHNEANGEDNNDGESHNRSWNCGAEGPTDDEAVKALRARQQRNFLTTLLLSQGVPMICHGDELGRTQNGNNNGYCQDNELTWIDWANADAGLLEFTRTVSALRAEHPVFRRRRFFSGKPVGRRGQGGLPDIAWFTPDGTEMSDEDWGAGFAKSVAVFLNGHGIPGRDERGQRVLDDSFLLCFNAHHEPIEFTLPPKEFGAAWQVVVYTGPDETTPADEVPGGGTLNVEAHTAVVLQGLPSS
>NC_016947.1|WP_009954047.1|4165281_4166463_-|glutathione-dependent-formaldehyde-dehydrogenase
MKAVTWHGKRDVRVESVPDPKIEQPTDAIVEVTSTNICGSDLHLYEILGAFMKPGDILGHEPMGIVREVGTQTGDLRVGDRVVIPFQISCGSCYMCGQQLYTQCETTQVRDQGMGAALFGYSELYGEVPGGQAELLRVPQAQFTHIKVPVGPPDSRFVYLSDVLPTAWQAVAYADIPEGGTVTVLGLGPIGDMAARIADHLGYRVIAVDLVPERLGRAAQRGIHTIDVGRLDSSLGDAIRDLTDGRGSDSVIEAVGMEAHGSPTAKLAQQATGLLPDALAKRLMQTAGVDRLSALYSAIDIVRRGGTISLIGVYGGMADPLPMLTLFDKQVTLRMGQANVKRWVDDIMPLLTDDDPLGVDTFATHVLPLDEAPHAYEIFQKKQDGAVKVILNP
>NC_016947.1|WP_026071237.1|4166522_4167230_-|GAF-and-ANTAR-domain-containing-protein
MRDGSATIANHLVELVANLEREHSGTAAGLHELLDDGVQHVTGAQYAGITLAEKGASVSSVVATHRYPMVLDAIQDTSGEGPCLAAAWEHHIMQITDLSAERRWLRYRRMALEQTPIRSILSFELFIDGGSMAALNFYADHPHAFSEESVEIGTVFATHIALAWSMMRRNDQFRSALASRDIIGQAKGVIMERFGIDAVEAFQLLTRVSQQSNIKLIEIARALIESEHPLKHRAH
>NC_016947.1|WP_009954051.1|4167538_4168849_+|NAD(P)/FAD-dependent-oxidoreductase
MTSIVIVGSGFTGFTCARRLARILRRRHAPVDITIISPVDYMLYTPLLPDVAGGVVDARFVAVPLANSLRGVHAVRGRVDGVDFAQQTLTYCDPEERSHSMSWDRLVLTPGSVTRLFDVPGLARHARGLKTTAEALYLRDHFVEQLELANIEDDPQVAAARRTVVVVGASYSGTELVAQLRALADAAAKQMGFNPAEVRFLLLDLAEQVMPEVGKKLGEAAMKVLRKRGIDVRLGVTLKQAHADHVVLSDDSRIDTHTIAWVTGVTGAPLIQDLGLPTEKGRITVQPDLQVPGHPEVFAAGDAAAVPDLTQPGQITPPTAQHATRQGKVLARNVAASLGYGSPKQYKHRNLGLVVDLGPRYAVANPLNIQLSGLPAKLVTRSYHLYAIPRGVNRWAVSLAYLTDVLFNRSVVSIGLSSEDDAQFTASEGIPMPKTS
>NC_016947.1|WP_009954052.1|4168852_4169389_-|DUF1360-domain-containing-protein
MGELTETGAQVVDGARKEADAYRGDNPRPLGGYLAVLVVYGLVVTAAVIAAVVSGRTLPSRWRIQDLIILTLGTHKLSRTLTKDAVTSPLRAPFTHYAGTGGPAEVQEEVREHSELRHSLGELLTCPFCLDMWVATGFAIGLVFVPRFTRLIAGVFSALAGADFLQLAYAMAQQSAEG
>NC_016947.1|WP_009954053.1|4169453_4169834_-|helix-turn-helix-transcriptional-regulator
MVEHRGEAGAPASGHGVYGISVAAELSGIPVQSLRLYERYGLLMPARSQGGTRRYSADDLARLRRISGLVEAGVNLAGIARILELEDDNETLAAANTDLRSTNRTLREAAKAAKPAESRDREGTRR
>NC_016947.1|WP_014380875.1|4169977_4170427_+|Hsp20-family-protein
MLMRSDPFRELDRFAHQVLGTAARPAVMPMDAWRQGEEFVVEFDLPGIDADSLDIDIERNVVTVRAERPALDPNREMLATERPRGVFSRQLVLGENLDTDKIQASYSEGVLSLHIPVAEKAKPRKIAVGRGDGHRAVAEGATQREVINA

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Crispr_ID: NC_016947_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016947_6

4838905-4839048

Orphan

Consensus_repeat	Method
GGTGAAACCAGGGCGGGAAAATCGCGAAAAGCTCGCCGTGAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_016947_6

>merge|NC_016947|6|4838905-4839048|CRISPRCasFinder
GGTGAAACCAGGGCGGGAAAATCGCGAAAAGCTCGCCGTGAGCTCACACCCAAAGCCCTGAGCTCACACTCGATGCCGCGGCGCGGCGGCCTACCCGCCGAAGGTGAAACCAGGGCGGGAAAATCGCGAAAAGCCCGCCGTGAG

>NC_016947|6|6|4838905-4839048|CRISPRCasFinder
GGTGAAACCAGGGCGGGAAAATCGCGAAAAGCTCGCCGTGAG	CTCACACCCAAAGCCCTGAGCTCACACTCGATGCCGCGGCGCGGCGGCCTACCCGCCGAA
GGTGAAACCAGGGCGGGAAAATCGCGAAAAGCCCGCCGTGAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_016947.1\|WP_009953511.1\|4833542_4834061_-\|mycothiol-transferase	unknown	unknown	gnl\|CDD\|368218
NC_016947.1\|WP_014381249.1\|4832677_4833532_-\|hypothetical-protein	unknown	unknown	unknown
NC_016947.1\|WP_014381254.1\|4842833_4843892_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|235337
NC_016947.1\|WP_008261338.1\|4848138_4848999_+\|CDP-diacylglycerol--serine-O-phosphatidyltransferase	unknown	unknown	gnl\|CDD\|224104
NC_016947.1\|WP_008261313.1\|4839119_4840745_-\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NC_016947.1\|WP_014381253.1\|4840920_4841613_-\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|376349
NC_016947.1\|WP_179293530.1\|4847419_4848142_+\|phosphatidylserine-decarboxylase	unknown	unknown	gnl\|CDD\|235400
NC_016947.1\|WP_014381256.1\|4844904_4846110_+\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NC_016947.1\|WP_008261301.1\|4834071_4834443_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319923
NC_016947.1\|WP_008261318.1\|4841642_4842134_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380345
NC_016947.1\|WP_014383369.1\|4830925_4832668_+\|cytochrome-c-biogenesis-protein-DipZ	unknown	unknown	gnl\|CDD\|239310
NC_016947.1\|WP_009953506.1\|4837451_4838015_+\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|367130
NC_016947.1\|WP_008261307.1\|4836943_4837345_+\|hypothetical-protein	unknown	unknown	unknown
NC_016947.1\|WP_008261321.1\|4842121_4842688_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380054
NC_016947.1\|WP_051049943.1\|4846136_4847354_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340951
NC_016947.1\|WP_009953510.1\|4834490_4836221_+\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|226179
NC_016947.1\|WP_014381252.1\|4838003_4838828_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223377
NC_016947.1\|WP_014381251.1\|4836260_4836905_+\|PPE-family-protein	unknown	unknown	gnl\|CDD\|366325
NC_016947.1\|WP_026071170.1\|4843934_4844885_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|235737
NC_016947.1\|WP_085977592.1\|4830126_4830813_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|375435

Protein	Function_ID	Function_description	E-value
NC_016947.1\|WP_009953511.1\|4833542_4834061_-\|mycothiol-transferase	gnl\|CDD\|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	4.1642e-24
NC_016947.1\|WP_014381254.1\|4842833_4843892_+\|alpha/beta-hydrolase	gnl\|CDD\|235337	PRK05077, frsA, esterase FrsA.	9.08651e-08
NC_016947.1\|WP_008261338.1\|4848138_4848999_+\|CDP-diacylglycerol--serine-O-phosphatidyltransferase	gnl\|CDD\|224104	COG1183, PssA, Phosphatidylserine synthase [Lipid metabolism].	2.87047e-70
NC_016947.1\|WP_008261313.1\|4839119_4840745_-\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NC_016947.1\|WP_014381253.1\|4840920_4841613_-\|aminopeptidase-P-family-protein	gnl\|CDD\|376349	pfam00557, Peptidase_M24, Metallopeptidase family M24. This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.	1.03483e-18
NC_016947.1\|WP_179293530.1\|4847419_4848142_+\|phosphatidylserine-decarboxylase	gnl\|CDD\|235400	PRK05305, PRK05305, phosphatidylserine decarboxylase family protein.	7.19973e-103
NC_016947.1\|WP_014381256.1\|4844904_4846110_+\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	9.39262e-154
NC_016947.1\|WP_008261301.1\|4834071_4834443_-\|VOC-family-protein	gnl\|CDD\|319923	cd07262, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	3.75378e-41
NC_016947.1\|WP_085977592.1\|4830126_4830813_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|375435	pfam17929, TetR_C_34, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in putative TetR family transcriptional regulators found in bacteria.	1.77175e-21
NC_016947.1\|WP_014383369.1\|4830925_4832668_+\|cytochrome-c-biogenesis-protein-DipZ	gnl\|CDD\|239310	cd03012, TlpA_like_DipZ_like, TlpA-like family, DipZ-like subfamily; composed uncharacterized proteins containing a TlpA-like TRX domain. Some members show domain architectures similar to that of E. coli DipZ protein (also known as DsbD). The only eukaryotic members of the TlpA family belong to this subfamily. TlpA is a disulfide reductase known to have a crucial role in the biogenesis of cytochrome aa3.	1.92988e-65
NC_016947.1\|WP_009953506.1\|4837451_4838015_+\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|367130	pfam02627, CMD, Carboxymuconolactone decarboxylase family. Carboxymuconolactone decarboxylase (CMD) EC:4.1.1.44 is involved in protocatechuate catabolism. In some bacteria a gene fusion event leads to expression of CMD with a hydrolase involved in the same pathway. In these bifunctional proteins CMD represents the C-terminal domain, pfam00561 represents the N-terminal domain.	2.62093e-05
NC_016947.1\|WP_026071170.1\|4843934_4844885_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|235737	PRK06197, PRK06197, short chain dehydrogenase; Provisional.	0
NC_016947.1\|WP_008261321.1\|4842121_4842688_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|380054	pfam17920, TetR_C_16, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. This entry represents the C-terminal domain found in a number of different TetR transcription regulator proteins found in Actinobacteria. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain.	1.66457e-22
NC_016947.1\|WP_051049943.1\|4846136_4847354_-\|MFS-transporter	gnl\|CDD\|340951	cd17393, MFS_MosC_like, Membrane protein MosC and similar proteins of the Major Facilitator Superfamily of transporters. The gene encoding Sinorhizobium meliloti membrane protein MosC is part of the mos locus, which encodes the biosynthesis of the rhizopine 3-O-methyl-scyllo-inosamine. MosC belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.77305e-73
NC_016947.1\|WP_009953510.1\|4834490_4836221_+\|amidohydrolase-family-protein	gnl\|CDD\|226179	COG3653, COG3653, N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism].	2.16227e-130
NC_016947.1\|WP_014381252.1\|4838003_4838828_-\|SDR-family-oxidoreductase	gnl\|CDD\|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	8.36501e-92
NC_016947.1\|WP_014381251.1\|4836260_4836905_+\|PPE-family-protein	gnl\|CDD\|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.02807e-52
NC_016947.1\|WP_008261318.1\|4841642_4842134_+\|cupin-domain-containing-protein	gnl\|CDD\|380345	cd02215, cupin_QDO_N_C, quercetinase, N- and C-terminal cupin domains. This family contains quercetinase (also known as quercetin 2,3-dioxygenase, 2,3QD, QDO and YxaG; EC 1.13.11.24), a mononuclear copper-dependent dioxygenase that catalyzes the cleavage of the flavonol quercetin (5,7,3',4'-tetrahydroxyflavonol) heterocyclic ring to produce 2-protocatechuoyl-phloroglucinol carboxylic acid and carbon monoxide. Bacillus subtilis quercetin 2,3-dioxygenase (QDO) is a homodimer that shows oxygenase activity with several divalent metals such as Mn2+, Co2+, Fe2+, and Cu2+, although the preferred one appears to be Mn2+. The dioxygen binds to the metal ion of the Cu-QDO-quercetin complex, yielding a Cu2+-superoxo quercetin radical intermediate, which then forms a Cu2+-alkylperoxo complex which then evolves into endoperoxide intermediate that decomposes to the product. Quercetinase is a bicupin with two tandem cupin beta-barrel domains, both of which are included in this alignment model. The pirins, which also belong to the cupin domain family, have been shown to catalyze a reaction involving quercetin and may have a function similar to that of quercetinase.	1.97239e-18

>NC_016947.1|WP_014381252.1|4838003_4838828_-|SDR-family-oxidoreductase
MALPAPSPTSTAVVTGASSGIGADIARELADRGHGLTLVARREDRLRDLADELAGRVRVEVIACDVADSAARAGLFDEVERRGLTADILVNNAGIGTMGSVTKIPVADEIAQVRVNVEAVIDLSTRAVQRMVPRGRGAILNVGSTAGYQPFPGQAGYAATKAFVNNYTHGLRGELAGTGVTVALLCPGPVRTEFVKSAGMDEREFADAFPKFMWKPSREVARAGVDALESDRPTVIPGLPSQISTRLFQFMPRRVLLPLLKNQHPSLRRDRSAG
>NC_016947.1|WP_009953506.1|4837451_4838015_+|carboxymuconolactone-decarboxylase-family-protein
MSRIAPLAPPWSEEDAAGINSWGHPDRTYEPLLLVRCLQRHPVLASRLRKLGESLYTAALLPPRTRTIAILRICALLRCAYEWGGQAAFWGPIAGVSDDECDALVLAGADDPRWGPAERTLIAAVDECERTGSWSEATWEALGDFLDDEQRIELLTAVGWYRTICTLCNALALPVEGWMRPWPGSAG
>NC_016947.1|WP_008261307.1|4836943_4837345_+|hypothetical-protein
MRSKKKVDFAALADALVDYPYAYLITVDDEYRSHTVTVEPELRGQTLEVGLIGGRTQQNLARRRDVTLLWPPAEPGGYSLIVDGAAEVSPEGGAGDAVRLTVTPTRALLHRDADSPDAARGCLHDCVVFSLPA
>NC_016947.1|WP_014381251.1|4836260_4836905_+|PPE-family-protein
MTNPHFAWLPPEVNSALIFSGPGPGPLLAAAAAWDGLAGELASSASSFSSVTSDLASGSWQGASSAAMMTVASQYVSWLSAAAAQAEEVSHQASAIATAFEVALAATVQPAVVAANRALVRALAANNHLGQNTPAIADIEAAYDQMWASDVAAMFGYHADASAAVAKLPPWNEVLQNLGFSNTTTAVTRPASSGAVARGYTSRIAGFLTPPAPQ
>NC_016947.1|WP_009953510.1|4834490_4836221_+|amidohydrolase-family-protein
MTYDLIIRNGTIVDGLGGEPYVGDVAVTDNVIKAVGDVNGAAANREIDATGLLVTPGFVDLHTHYDGQSIWSERLTPSSAHGVTTVVMGNCGVGFAPCRQSDHDVLVDVMAGVEDIPGVVMTDGLPWTWETFPEYMDALDAGKRDIDVAAYLPHSPLRVYVMGQRGADREPATEDDLAKMRALAKEAIEAGALGFASSRLTIHKTESGSPIPSYDAAREEIEQIARGVVDGGGGLLQFVPDIPAGGYQPVLQTVFDVAEDVGLPLTFTLVVANSGDPSWPDAITMIEKANAAGGDITAQLLPRPIGLIIGLQLSANPFVLYPSYREIAHLPLAERVAEMRKPEVRARILADKPGQGHPILYVAQMWDWIYPLGEDPDYEPDPSTSIGARARAKGVEPMEEAYDRLLDDDGKAMLLVATSNLQGNSLDTVGELLHRDDVVLGLGDGGAHYGMICDASYSTYFLTHWARDRKAGRFTVPEAVRELTSVPARIAGLSDRGRIAVGYKADLNVIDHAALRLHKPVITYDLPAGGRRLDQTADGYVATIVSGEIIAEHGVPTAARPGKLVRGRQPAPAPLQ
>NC_016947.1|WP_008261301.1|4834071_4834443_-|VOC-family-protein
MIDHVGINCADYAKSQRFYDAVLETLGFSRQLDVGPAIGYGRGGKPTFWISGALAGPNREVHLAFEAPDEDAVRAFYRVAVELGAEPLHEPRLWPEYHPGYFGAFVRDPDGNNVEAVFHGALP
>NC_016947.1|WP_009953511.1|4833542_4834061_-|mycothiol-transferase
MARTDDAAVIQDLLRDAFTRLIEHVDEITEGLTEEVSSYRPTPDANSIAWLLWHSARVQDLQLADVAGVEQVWLRDGWVDRFGLDLPQGDMGYGHSPDDVAKVKAPADLLSGYYHAVHELTLEYLGGITAEELARVVDTNWDPPVTASARLVSIIDDCAQHLGQAAYVRGIA
>NC_016947.1|WP_014381249.1|4832677_4833532_-|hypothetical-protein
MRFAASVLLWLITTLALAVAIPAAWTQLHVVDADGYAALARGAAADPDLQSAMAAELTTRAMALIAEHGGGRYPVDSSDVHDAASAFTAGPAFPPLFAQANRAAHGWLFGDPGGGENGDQWAVDVAPMLGDDSIRPLLSRYNVTVPAKLAVPLTVSMPQAMRQGRLSRLSTWGPWVSVGAAALCGVCALLTLAAARRRGKALSSLGVSALLVGAAGWAGLEVAGRYVDKALNRTTGDIRRVAEAMVGHAEAGVHQWLNVTLLAGAALVGLGVVVAMVGSLWKKS
>NC_016947.1|WP_014383369.1|4830925_4832668_+|cytochrome-c-biogenesis-protein-DipZ
MQTIALIGFLGGLITGISPCILPVLPVILLSGAGGTRADSRRVSSVSRPYLVIAGLVCSFSLATLLGSALLTALHLPHDAIRWAALVVLTLIGLGLIFPPVQHLIERPFAYLPQRQIGANADGFGLGLTLGALYVPCAGPVLAAIVVAGGTSSIGPGALVLTATFALGNAVPLLAFALAGRRVAERIAAFRRRQRAIQIAGGIAMIVLAVALVFNLPAMLQRAVPDYTTAMQNKLGANDIGHSLNPTPAQQPNRGTGLALSPPSVTVEGALSDCSSGSDELQQCGPAPALTGVTGWLNTPDGKPLDPAEVRGKVVLIDFWAYSCINCQRAIPHVTDWYNRYHDAGFVVIGVHTPEYAFERVPENVASGAADLHIPYPIALDNDYATWNNFHNLYWPAEYLIDANGQVRHTKFGEGDYDGTEKLIRQLLADAHPGAPLPAPTSSADTTPQTRLTPETYLGVERSGNYGGTGDYTSGTVTLSFPPTLADDTFALRGRWTLDDQGATAEGDDATVRLNYTAKDVYAVIGGTGTLTVTRDGTTTTTPIGGAPTLHRIVADDSAHRDQLDMRVSKGLQVFSFTFG
>NC_016947.1|WP_085977592.1|4830126_4830813_-|TetR/AcrR-family-transcriptional-regulator
MRYALPVAQLTFQRARTEEKKRQRAEALVEAARSLAMETGVASVTLTAVASRAGIHYSAVRRYFTSHKEVLLRLSAEGWVRWSNTVSDKLAEPGAKSPSRIAGTLAEALADDPLFCDLLANLHLHLEHEVDAERVIEVRRISTAATRSLADAIERALPELGRSGSLDILLAAYSLAATLWQVANPPADLTDVYAEEPEVAPPEWNLDFATALTRLLTATCIGLITEAA
>NC_016947.1|WP_008261313.1|4839119_4840745_-|chaperonin-GroEL
MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETKDQIAATAAISAGDQSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISGYFVTDAERQEAVLEDPFILLVSSKVSTVKDLLPLLEKVIQAGKPLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVISEEVGLSLESADVALLGKARKVVVTKDETTIVEGAGDSDAIAGRVAQIRSEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALLHATPSLDELKLTGDEATGANIVRVALEAPLKQIAFNGGLEPGVVAEKVRNSPAGTGLNAATGEYEDLLKAGVADPVKVTRSALQNAASIAGLFLTTEAVVADKPEKAAAPVGDPTGGMGGMDF
>NC_016947.1|WP_014381253.1|4840920_4841613_-|aminopeptidase-P-family-protein
MEAAEELRVERLLDAERKAAQLFDEIERRAMIRSGVGEKELSDEIHDLAGEMFGVTRHWHRRIVRAGENTLQPFHERPPDRLIVDDDIVFLDLGPIFEEWEADFGRTFLLGDDPHKRAVRDALPRVWQAGRDYFAGNPDVTGAELFDFVVGAAHAEGFEWASRIAGHLVGEFPHKKIAGPGIEWYIMPGSDKPMRRTDPRGRICHWILEIHLVDRPRGFGGFYEQLLDLP
>NC_016947.1|WP_008261318.1|4841642_4842134_+|cupin-domain-containing-protein
MSLVVPPYPPARYTAEEPEISAWLKRADQPPDYETSGVKYHYLANQQDTAGDYGLYRVDIAPAGGGPPAHFHRAMSEAFFVLSGTMKLYDGTEWADGHQGDFLYVPPGGVHGFRNEADEPASILMLFAPGAPREAYFEGFAALADMTDEERREWFVRHDNYWV
>NC_016947.1|WP_008261321.1|4842121_4842688_-|TetR-family-transcriptional-regulator
MLAARIAAAARDEFAVHGWAGTTIRAVARRADVDPALVYHYFGSKEGLLDAATNPPQQWLDRVAEVWATPVERLGAALLQLLLASWADDEIGPTLRAILQTAAHDPATRDKLRRVVEGSLMGVSGLGSDDRDRLIRSGLISSQMMGFALMRYVWKIEPVASMTDDEAIAAIAPNLQRYVDGDLGGQTQ
>NC_016947.1|WP_014381254.1|4842833_4843892_+|alpha/beta-hydrolase
MYTYDIDAAAMFDDRTDQFAKFGVPLEDIERVRSAVDDMWDDAPGGWVYEWSRVARDYAERGDHRMASLVYGCAKFPCLTDAARVKALQHQLEQFQLAANGFPVHFERRIVAVGYRGGSVEVPVHLYSADGRYADRAVLIASGGVDTWKMDIHPWWVGFTQGAGVTTLAFDHPGTGETDIPLDEHADEVIRGLIGYARTLGDGRVAHFGASFGGNFAAMSGLTGIVDAAIELGGPVVDAFAVENIAKLPYGMRDIVGNAMHWDHSPTLEELSAGLSRLNRRDLLARQGNSEMLVINGADDYFVPQSDTLVFQGRPDTEVHLIEGTGHVAMSKAPEVVPRVIAWLRAQMTTER
>NC_016947.1|WP_026071170.1|4843934_4844885_+|SDR-family-NAD(P)-dependent-oxidoreductase
MASNDKETRAWSESDVPDQSGRVVVITGANTGIGYEAAAVLAHRGAHVVLAVRNLEKGNAALSRIVAAGGQGPREVDVTLQQLDLTSLDAVRSAADALRAAYPRIDLLINNAGVMWTPKQVTADGFELQFGTNHLGHFALTGLLLDHLLPVRDSRVVTISSLGHRLRAAIHFDDLQWEHRYDRIAAYGQSKLANLLFTYELQRRLAATPDAKTIAVAAHPGGSNTELTRNLPAIFRPAAAALGPVLFQSAAMGALPTLRAATDPDVQGGQYFGPDGFLEQRGHPKLVKSSAQSHDAELQRRLWAVSEELTGVRFPV
>NC_016947.1|WP_014381256.1|4844904_4846110_+|molybdopterin-molybdotransferase-MoeA
MRSVAEHQRVVTDLIRPRPPVSVALTDAQGLVLAEDVIAQLALPVFDNSAMDGYAVRAEDTASATPENPVVLPVAEDIPAGRTDELTLQPGTAHRIMTGAPLPAGATAIVPVEATDGGVDVVSIREPREAGKHIRCAGEDVAPGTTVLRRGQVVTPAVLGLAAALGIAELPVIPRQRVLVISTGSELVTPGVPLRPGQIYESNSIMLAGAVRDAGADLVAVATAEDDVAQFSSIIDRYAADSDLIITSGGVSAGAYEVVKDAFGREGDQGVEFVKVAMQPGMPQGVGRVAGATIVTLPGNPVSALVSFEVFIRPALRTAMGLPDPERPHRSAVLAESLTSPRGKRQFRRAVLSDDASSVTSYGPPASHHLRWLASANGLLDIPEDVVEVPEGTRLQVWDLR
>NC_016947.1|WP_051049943.1|4846136_4847354_-|MFS-transporter
MQPHSADRRATPVRRAKRGVTAAFIAHGLVFSSWAAHIPRVKDELGLSDAALGTALFGAPLGSVVATLASHWALRRWGSHRLIPVMAAGYAVAGTTVGLAKSGAALFGALALWGTFQGALDVAMNTQAATVERAARAPIMARFHGMWSVGTLVGAVIGAACVGAGIGLTAQLTVLGAVVLIVVGTLTRRLIPDAADDSDASSGPTPQGRRAWMTPTVAILAAVSFASFLCEGAATDWSANYLRNVVGAGPSVSALSYAAYTLTMVITRFGAPRLHARVPSRRLLPALAVVAVAGISVTLATANAAVGVLGFAALGVGVALLVPTAFSAAYGASEAGSAIAIVAATGWLGYLLGPPLIGHLSGWVGLSAALATIPVMMSIVGIAIRYNPAFDKADEFHRDVATPAG
>NC_016947.1|WP_179293530.1|4847419_4848142_+|phosphatidylserine-decarboxylase
MARRPRTIGPTASDPGFSPQHALELVRSAVPPVHPAGRPFIGAGLALALAGRRHRWVRRAGLLAAGACAGFFRHPPRVPPTRPGAVVAPADGEICVIDFATPPAELSMGDAALPRVSIFLSLLDAHVQRAPVSGEVIAVQHRPGRFGSADLAAASTENERTSLVIRTPGGADVVAVQVAGLLARRIICDAHVGDKLSIGDTYGLIRFGSRLDTYLPAGCEPLVKVGQRAIAGETVLAELP
>NC_016947.1|WP_008261338.1|4848138_4848999_+|CDP-diacylglycerol--serine-O-phosphatidyltransferase
MISKPRGRAVNLQILPSAMTVLSVCAGLTSIRFALEHQPKAAMALIAAAAILDGLDGRVARILDAQSRMGEEIDSLADAVNFGVTPAIVLYVTLLTNSPAGWVVILLYAVCVVLRLARFNALQDDGSQPAYTHEFFVGMPAPAGAISMIGLIGLKLQFGDGWWTSPLFLCIWITGTSILMVSKIPMRKMHAVAVPPSWAAPLLAILAICAAAAVLAPYVLIWVIIIAYLCHVPFAIRNQRWLAAHPEAWDDEPKQRRATRRAIRRAQPNRRSVARLGLRKPGRRVP

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Crispr_ID: NC_016947_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016947_7

4955216-4955343

Orphan

Consensus_repeat	Method
ATCGCCGGCGGCGCCAAGAAACCCGGGGCCAAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_016947_7

>merge|NC_016947|7|4955216-4955343|CRISPRCasFinder
ATCGCCGGCGGCGCCAAGAAACCCGGGGCCAAGAAAGCCGCGCCCGCCGCGGAAGGCAAGGCCGAAGCGGCCGCCCCGGTCAAGGGGCTGGGCATCGCCGGCGGCGCCAAGAAACCAGGGGCCAAGAA

>NC_016947|7|7|4955216-4955343|CRISPRCasFinder
ATCGCCGGCGGCGCCAAGAAACCCGGGGCCAAGAA	AGCCGCGCCCGCCGCGGAAGGCAAGGCCGAAGCGGCCGCCCCGGTCAAGGGGCTGGGC
ATCGCCGGCGGCGCCAAGAAACCAGGGGCCAAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_016947.1\|WP_009954017.1\|4955829_4957134_+\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|181738
NC_016947.1\|WP_009954020.1\|4950904_4952581_+\|Hsp70-family-protein	unknown	unknown	gnl\|CDD\|223520
NC_016947.1\|WP_080552513.1\|4962824_4963289_-\|TauD/TfdA-family-dioxygenase	unknown	unknown	gnl\|CDD\|181947
NC_016947.1\|WP_009954032.1\|4942103_4942745_-\|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl\|CDD\|237623
NC_016947.1\|WP_009954030.1\|4944919_4945513_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237874
NC_016947.1\|WP_009954013.1\|4960587_4961244_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225136
NC_016947.1\|WP_008261532.1\|4940875_4942054_-\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|237655
NC_016947.1\|WP_026071153.1\|4946864_4947437_+\|hypothetical-protein	unknown	unknown	unknown
NC_016947.1\|WP_179293542.1\|4964822_4966238_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237030
NC_016947.1\|WP_179293540.1\|4948208_4949666_-\|sugar-porter-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340917
NC_016947.1\|WP_179293541.1\|4950223_4950808_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|252996
NC_016947.1\|WP_009954031.1\|4942741_4944601_-\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|234715
NC_016947.1\|WP_026071152.1\|4947426_4948161_+\|hypothetical-protein	unknown	unknown	unknown
NC_016947.1\|WP_009954015.1\|4959327_4959702_-\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|378915
NC_016947.1\|WP_009954016.1\|4957166_4958432_+\|YibE/F-family-protein	unknown	unknown	gnl\|CDD\|377940
NC_016947.1\|WP_009954014.1\|4959731_4960487_-\|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	unknown	unknown	gnl\|CDD\|274422
NC_016947.1\|WP_008261583.1\|4963400_4964726_-\|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|223936
NC_016947.1\|WP_009954012.1\|4961483_4962806_+\|MHS-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340927
NC_016947.1\|WP_014381307.1\|4945624_4946854_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377558
NC_016947.1\|WP_008261569.1\|4958428_4959304_-\|glucose-1-phosphate-thymidylyltransferase-RfbA	unknown	unknown	gnl\|CDD\|130274

Protein	Function_ID	Function_description	E-value
NC_016947.1\|WP_009954017.1\|4955829_4957134_+\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|181738	PRK09265, PRK09265, aminotransferase AlaT; Validated.	0
NC_016947.1\|WP_009954020.1\|4950904_4952581_+\|Hsp70-family-protein	gnl\|CDD\|223520	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones].	1.27594e-32
NC_016947.1\|WP_080552513.1\|4962824_4963289_-\|TauD/TfdA-family-dioxygenase	gnl\|CDD\|181947	PRK09553, tauD, taurine dioxygenase; Reviewed.	1.369e-37
NC_016947.1\|WP_009954032.1\|4942103_4942745_-\|nucleotide-exchange-factor-GrpE	gnl\|CDD\|237623	PRK14142, PRK14142, heat shock protein GrpE; Provisional.	3.78199e-100
NC_016947.1\|WP_009954030.1\|4944919_4945513_+\|hypothetical-protein	gnl\|CDD\|237874	PRK14971, PRK14971, DNA polymerase III subunit gamma/tau.	4.50153e-07
NC_016947.1\|WP_009954013.1\|4960587_4961244_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	1.29167e-26
NC_016947.1\|WP_008261532.1\|4940875_4942054_-\|molecular-chaperone-DnaJ	gnl\|CDD\|237655	PRK14279, PRK14279, molecular chaperone DnaJ.	0
NC_016947.1\|WP_009954012.1\|4961483_4962806_+\|MHS-family-MFS-transporter	gnl\|CDD\|340927	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.26975e-134
NC_016947.1\|WP_179293542.1\|4964822_4966238_-\|hypothetical-protein	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	1.87892e-14
NC_016947.1\|WP_179293540.1\|4948208_4949666_-\|sugar-porter-family-MFS-transporter	gnl\|CDD\|340917	cd17359, MFS_XylE_like, D-xylose-proton symporter and similar transporters of the Major Facilitator Superfamily. This subfamily includes bacterial transporters such as D-xylose-proton symporter (XylE or XylT), arabinose-proton symporter (AraE), galactose-proton symporter (GalP), major myo-inositol transporter IolT, glucose transport protein, putative metabolite transport proteins YfiG, YncC, and YwtG, and similar proteins. The symporters XylE, AraE, and GalP facilitate the uptake of D-xylose, arabinose, and galactose, respectively, across the boundary membrane with the concomitant transport of protons into the cell. IolT is involved in polyol metabolism and myo-inositol degradation into acetyl-CoA. The XylE-like subfamily belongs to the Glucose transporter -like (GLUT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.64333e-98
NC_016947.1\|WP_179293541.1\|4950223_4950808_+\|hypothetical-protein	gnl\|CDD\|252996	pfam05086, Dicty_REP, Dictyostelium (Slime Mold) REP protein. This family consists of REP proteins from Dictyostelium (Slime molds). REP protein is likely involved in transcription regulation and control of DNA replication, specifically amplification of plasmid at low copy numbers. The formation of homomultimers may be required for their regulatory activity.	7.66132e-05
NC_016947.1\|WP_009954031.1\|4942741_4944601_-\|molecular-chaperone-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NC_016947.1\|WP_009954016.1\|4957166_4958432_+\|YibE/F-family-protein	gnl\|CDD\|377940	pfam07907, YibE_F, YibE/F-like protein. The sequences featured in this family are similar to two proteins expressed by Lactococcus lactis, YibE and YibF. Most of the members of this family are annotated as being putative membrane proteins, and in fact the sequences contain a high proportion of hydrophobic residues.	1.31151e-76
NC_016947.1\|WP_009954015.1\|4959327_4959702_-\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	0.000435505
NC_016947.1\|WP_009954014.1\|4959731_4960487_-\|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	gnl\|CDD\|274422	TIGR03083, TIGR03083, uncharacterized Actinobacterial protein TIGR03083. This protein family pulls together several groups of proteins, each very different from the others. They share in common three conserved regions. The first is a region of about 38 amino acids, nearly always at the N-terminus of a protein. This region has a bulky hydrophobic residue, usually Trp, at position 29, and a His residue at position 37 that is invariant, so far, in over 150 instances. The second conserved region has a motif [DE]xxxHxxD. The third conserved region contains a hydrophobic patch and a well-conserved Arg residue. Most examples are found in the Actinobacteria, including the genera Mycobacterium, Corynebacterium, Streptomyces, Nocardia, Frankia, etc. The pattern of near-invariant residues against a backdrop of extreme sequence divergence suggests enzymatic activity and conservation of active site residues.	4.08521e-17
NC_016947.1\|WP_008261583.1\|4963400_4964726_-\|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	gnl\|CDD\|223936	COG1004, Ugd, Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane].	0
NC_016947.1\|WP_014381307.1\|4945624_4946854_+\|hypothetical-protein	gnl\|CDD\|377558	pfam05818, TraT, Enterobacterial TraT complement resistance protein. The traT gene is one of the F factor transfer genes and encodes an outer membrane protein which is involved in interactions between an Escherichia coli and its surroundings.	0.00637593
NC_016947.1\|WP_008261569.1\|4958428_4959304_-\|glucose-1-phosphate-thymidylyltransferase-RfbA	gnl\|CDD\|130274	TIGR01207, Glucose-1-phosphate_thymidylyltransferase_1, glucose-1-phosphate thymidylyltransferase, short form. Alternate name: dTDP-D-glucose synthase homotetramer This model describes a tightly conserved but broadly distributed subfamily (here designated as short form) of known and putative bacterial glucose-1-phosphate thymidylyltransferases. It is well characterized in several species as the first of four enzymes involved in the biosynthesis of dTDP-L-rhamnose, a cell wall constituent and a feedback inhibitor of the enzyme. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0

>NC_016947.1|WP_009954020.1|4950904_4952581_+|Hsp70-family-protein
MSQSLGLSIGVANLVAARAGTAPVTRSSVVTLFEHRPTEVGLPEENPNLTAPGLVLRGFVERVGDRAPLVAADGTKYLGAALTVEAIEAMARTVGYGTPISIAVPAYWSDEQFAALRDEFFAQSDLARGGVAPMLVSDATAAVAALRGTPGFPADGVVALCDFGAGGTTVTVLDANAGFAPVAPAVRHTDFSGDAIDQLIVDHLLASDVSTAVLGGGARMGSQTRLLAACRRAKEQLSTAAVSTVAGASGESTQLTRTEFEQLISPPLDRFVTSLQDTLRRNGIPNTNLRAVAIVGGGASIPLITARLSQRFGVPVRSAAQPASLAALGAAALGAQYAAGGAETTAAAAVETPTEMVGTAGIGATQAAWAAQATDVDDALAWSQDADSDEPVPYTGRDATGEYASEAREFEYPEQGGLPWYKRTALVLTVAGAGVAVLVAAALAIGLLMTKSTPAPPTSSPNPPPPPQTVTITGPNDSTTVTVVPAPPPPSSEAPATTTTTTPPPEPSTTTTTPPPSTTTTTTAPPTTTSQVTTTSAAPTTTTRVRPLPPIFQPPFGR
>NC_016947.1|WP_179293541.1|4950223_4950808_+|hypothetical-protein
MSRLAGAVSTIGAVASNGPRDDFHNRPTQHADFGMSEPPTGEVPPPNFPPQPPHGFEQPQGFDPFDQEPEPTPWYRRPAMLIAWLISVVILIGLIVFGIIELIHDDQSVNHVPKSTTSTTTTTTTTTPSTTTTTTTTESSSSAEEQPPAQQPTQQQPTGQQTQQPTHRHHLPQLPPVITIPQVPTVITVPPGLR
>NC_016947.1|WP_179293540.1|4948208_4949666_-|sugar-porter-family-MFS-transporter
MPNGTDPAKCADAAHEGASQRAVGAVAEAGSQLTSAVVVIALVSAISGLLYGYNTGVISWALLQLTEEFNLTAAWKQVVAASILLGAIVGALACSWLSDRFGRRGTLLMLAVLFIVGALWCADAPDVVVLSLGRLVLGFAVGGATQTAPMYVAELSPSAYRGRLVLCFQIAIGVGILAANLIGVFDSVSWRGPTGIACVPAAIMLWLLLRLPESPRWLVKQGDRNAARAVLERVRPDGYDVGAELDEATELARMERKASTRGWSGLRDAWVRPALVLGCGIAVFTQLSGIEMIIYYAPTILTDDGVYRSVALLVSVMLGATYVIAQLVGLAIIDRVGRRRLTLIMVPGAAISLFALGLIFVTADSGRDVIAYIMISLIAFMVFNAGGLQLMGWLTGSETYPLAVRPEGTAVHSATLWGTNLLITLTLLSLINAIGVGPSMWLYALFNVAAWIFVFFRMPDLTGKSLEEIEKNLAEGKFRPSDFAR
>NC_016947.1|WP_026071152.1|4947426_4948161_+|hypothetical-protein
MASNTAKRRVPKLRYAVGGALCLLAGINVLVGSAWYLPVGAAAVGVGIIYGSGRRIFGAGVRRTGQEIVCRYLPWYESNPYMATLLFPLIAIAMIGAGCAPGNPAWLWYGGAILLAISALLVGVSLWIWRRSLLRITPAALTVRIAERGSELTDIRREHVRSIEPKLVPSVAAGTERLQVEVAYQPADVSSEATATVMLGMYLSVQPINLLNALVAWKDGAHDNPSELLDRIERILRGQSMAGV
>NC_016947.1|WP_026071153.1|4946864_4947437_+|hypothetical-protein
MRFDEFTEEHGLAVSPVDRFVGFVVEVGVPPGWEPFESAEGVRVWVCRADPCIDVFCANAVLTMHRVEASLDPPEVFAMLSDQQLQSAPKCRELHREFTAAREGPGSAGTLAIQIAHELGTIDSTSQSRIITAERETLIAQLTVTALHDSPMDGSGVWLTTRSGPVTNPTSAGYHGAIPRTEHGTVADGK
>NC_016947.1|WP_014381307.1|4945624_4946854_+|hypothetical-protein
MQLRYISVAALIAEAGGDPWAVNQSLQAGSPFQIAQLAEAFLKAGRCTAEATNAFDQARSRFDAAWNHQNGDHPINGSAEVQRVTKSLGAQSLQLPKIGADLENIAANLAEAQKSAAGQIAALESQLQQLDGFIGQAVELEKDPTLTAEDRHALDAFISGREDDAIRDTKAALGQLQSTRDGYANSFQNAMGTLHADGYDLTAPQTGPAQGAAEQPGGGAAEQPGGGPALAPTKGEVLTGAAGAIAGGTADGVRGATTRLIAESPGTGPGKADPGLLRWFEDPKIGGIELKGFSRVGGVVAAASAVPAVMSDIHDGNSVPEAVTRESAGVAAGLAAGGWVGGAVAGSELGAALGSVVPGAGTAVGLVAGAVVGAGAAFVASKTVEVAWQPAADAIGSVVHGVESVFGFG
>NC_016947.1|WP_009954030.1|4944919_4945513_+|hypothetical-protein
MRFSDNVRRSLAGGSLLLVALFAGSGLVSGCSSVIGGRPVASPGAGAGEPSFPTPRSTPSPPSATAAPAPTAPAAPTGPTNPAGAIPLPPDQNGYVFIETKSGVTRCQINKDTVGCEAPFTNSPLQDGEHANGVSVTTGGKVQWVLGNLGAIPTVKIDYQTYAAQGWTIIANVDGTRFTNDQTKHGMFVSIDKVNTF
>NC_016947.1|WP_009954031.1|4942741_4944601_-|molecular-chaperone-DnaK
MARAVGIDLGTTNSVVAVLEGGDPVVVANSEGSRTTPSIVAFARNGEVLVGQPAKNQAVTNVDRTIRSVKRHMGTDWSIEIDDKKYTAQEISARVLMKLKRDAEAYLGEDVTDAVVTVPAYFNDAQRQATKEAGQIAGLNVLRIVNEPTAAALAYGLDKGEKEQTILVFDLGGGTFDVSLLEIGEGVVEVRATSGDNHLGGDDWDDRVVDWLVDKFKGTSGIDLTKDKMAMQRLREAAEKAKIELSSSQSTSINLPYITVDADKNPLFLDEQLTRAEFQRITQDLLDRTRQPFQSVIKDAGISVSEIDHVVLVGGSTRMPAVTELVKELTGGKEPNKGVNPDEVVAVGAALQAGVLKGEVKDVLLLDVTPLSLGIETKGGVMTKLIERNTTIPTKRSETFTTADDNQPSVQIQVYQGEREIASHNKLLGSFELTGIPPAPRGVPQIEVTFDIDANGIVHVTAKDKGTGKENTIKIQEGSGLSKEEIDRMIKDAEAHAEEDRQRREEADVRNQAESLVYQTEKFVKDQREAEGGSKVPEDTLSKVDAAIAEAKTALGGTDITAIKSAMEKLGQESQALGQAIYEATQAAGEQTDATGGGQAGSADDVVDAEVVDDDRESK
>NC_016947.1|WP_009954032.1|4942103_4942745_-|nucleotide-exchange-factor-GrpE
MTEGNPQEQVTVTDKRRIDPETGEVRQVPPGDTPGGPAPADEPAVQGEGKLAELTADLQRVQADFANYRKRALRDQQAAADRAKAAVVNQLLGVLDDLDRARKHGDLESGPLKAVADKLEGALTGLGLTAFGEEGEDFDPVLHEAVQHEGDGSRPVIGTVMRQGYKLGDQILRHAMVGVVDTVDDEGDESASAGEAEETAPVESDDNAGTSGD
>NC_016947.1|WP_008261532.1|4940875_4942054_-|molecular-chaperone-DnaJ
MAQREWVEKDFYKELGVSSDASPEEIKRAYRKLARDLHPDANPDNPAAGERFKAVSEAHNVLSDPAKRKEYDETRRLFAGGGFGGRRFDTGGFGGFNVGGDGAEFNLNDLFDAAGRSGGTNIGDLFGGLFGRGAGGRPSRPRRGNDLETETQLEFVEAAKGVAMPLRLTSPAPCTNCHGSGARPGTSPKVCPTCNGSGVINRNQGAFGFSEPCTDCRGSGSIIEHPCEECKGTGVTTRTRTINVRIPPGVEDGQRIRLPGQGEAGLRGAPSGDLYVTVHVRPDKVFGRDGDDLTVTVPVSFTELALGSTISVPTLDGKVGVRVPKGTSDGRILRVRGRGVPKRSGGNGDLLVTVKVAVPPNLEGAAQEALEAYAAAERSSGFDPRAGWAGNR
>NC_016947.1|WP_009954017.1|4955829_4957134_+|pyridoxal-phosphate-dependent-aminotransferase
MDSDGTIGDVTTHQLPHQLPPHPSAHHRQQRTFVQSSKLQDVLYEIRGPVHQQAARLEAEGHRILKLNIGNPAPFGFEAPDVIMRDMIQALPYAQGYSDSQGILPARRAVVTRYELVDGFPRFDVDDVYLGNGVSELITMTLQALLDNGDEVLIPSPDYPLWTASTSLAGGTPVHYLCDETQGWQPDIADMESKITDRTKALVVINPNNPTGAVYTSEVLTQIVELARKHELLLLADEIYDKILYGDAKHINLASLAPDMLCLTFNGLSKAYRVAGYRAGWLAITGPKDHAGSFIEGINLLANMRLCPNVPAQHAIQVALGGYQSIDDLVLPGGRLLEQRDVAWTKLNEIPGVSCVKPDGALYAFPRLDPEVYDIDDDEQLVLDLLLQEKILVTQGTGFNWPAPDHLRIVTLPWARDLAAAIERLGNFLVAYRQ
>NC_016947.1|WP_009954016.1|4957166_4958432_+|YibE/F-family-protein
MTHSHSHSLPPGPSGIDPLPARIVVGLLVAIGVAVAVGAILLWPSRQRVDIPMPLQNASGGAVSTQAGHVLSSGLGDCGSPSVSQVLTGPPKPAAPGAGRCVLTQVAVDSGPNAGATTLLESSPGPGQPKFAVGDRIRVVRQVDDQGATSYAFYDFERGWALVGLAIAFAVVIVAVARWRGLLALVGILVAFVVLVMFLLPALRDGAPAVPVALVASAAILYAVIYLAHGVSLRTSAALLGTLSALLLAAGLSWAAIQLAHLTGLSDEQNTTVSAYLGNVSIGGLLLAGFIIGSLGVLNDVTVTQSSTVFELARLGGSRRAIFVGAIRVGRDHIASTVYTLVLAYAGSSLPLLLLFSVANRSLTDVLTGESVAIEIARSAVGGMALALSVPLTTGIAAVLAKPSGGRKRGEAARSGPPPPA
>NC_016947.1|WP_008261569.1|4958428_4959304_-|glucose-1-phosphate-thymidylyltransferase-RfbA
MRGIILAGGSGTRLHPITTGISKQLLPVYDKPMVYYPLSTLMMAGIRDILVITTPHDAPGFQRLLGDGSQFGVNITYVTQDRPDGLAQAFVLGADHIGNESVALVLGDNIFYGPGLGTSLRRFQTISGGAVFAYWVANPSAYGVVEFSDDGLALSLEEKPKTPKSNYAVPGLYFYDNDVIEIAKGLKKSARGEYEITEVNQIYLNRGRLSVEVMARGTAWLDTGTFDSLLDASDFVRTLERRQGLKVSVPEEVAWQQGWITDEQLAQRAHSLLKSGYGSYLLNLLERSRFH
>NC_016947.1|WP_009954015.1|4959327_4959702_-|nuclear-transport-factor-2-family-protein
MTTSEIATVLAWHDALNAADIETLASLSSDDIEMGDAHGAAQGHEALRSWAASHRPATELGRMYVHDGVVAVELKPGSTGDPGAATDAALTFRVVRDHVTSVFRHDSLASALAATELTESDAVD
>NC_016947.1|WP_009954014.1|4959731_4960487_-|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme
MDYAGAFLDQNRAFAELFDGADESTPVPTCPEWTLRQLFRHVGRGDRWAAQIVRDRLESYLDPRTVEGGKPPPDPADAISWLHGGAQRLVDAVELTGVETPVWTFLGPRPANWWIRRRLHEVAVHRADAAIALGTDFALEPDIAADGITEWLERVAIQAGGQGAPLPLEDGTTLHLHATDPGLGEAGEWTAAVDQGRVTWSHEHGKGSVALRGGATELLLAILRRRPLADTGVQLFGDEAVWERWLDRTPL
>NC_016947.1|WP_009954013.1|4960587_4961244_+|class-I-SAM-dependent-methyltransferase
MLADSAGLPDAHAAIRAFWEREGSEYDQRAAHGISSEPERRLWTAALSAIPERSRVLDIATGTGFVALLLSELGHRVTGVDASEAMLARARAKAAATAATVEFVEGVTEELPFPDASFDALTARHFIWTLLEPEKAFAEWRRVLAPDATLIADVSLNPHVAGHHYADDVAAALPFRALSDAAPVADALRSAGFEHVRIDLSRDGGEYPRAMLHARAGQ
>NC_016947.1|WP_009954012.1|4961483_4962806_+|MHS-family-MFS-transporter
MTIAEQESSRAATPPEEAAPVPDMRRVALASLAGSVLEWYDFFLYGFAATLVFGPLFFPRASATAGVLAALGTFAVGFVARPLGGVVFGHLGDRLGRKKMLVATLLIMGIPSFLIGLLPSYSAIGWSAPALLVLLRFLQGVGLGGEWAGAVLVVTETSPPHRSGFWGSLVQTGATLGQGLATGSLFILASLLSEHSFVTWGWRVPFLFGIALSVVGLFIRLRVMESPEFTALHRSGELSRFPLREAVRQHGRTMLVCFGVYLGGVTVPFFVETVFLTGYGTKSLALPASSVLLGISAVHVTVFWVLTLLGGWLADRVGAPRVVRAGLLGLLVLPTAGLLAVLSASSTVAALLITETLIGAPMWVVWGALPKYLAESFPARVRYTGMSLSGQSSTIIGGLIPLLLTSVIAHVGGALWPVALTTTAVAAFGVLGLLWSHRSR
>NC_016947.1|WP_080552513.1|4962824_4963289_-|TauD/TfdA-family-dioxygenase
MVRGFIDGLRAEHRFGATLAFERSAEKIGELVRGKPLAAIHPVVRVHPETNERVVYVNQFFTKEIVDLSPRESRHVLGLLFEQISRPEYSVRFKWEPGSVAFWDNRATLHLAPRDFEHLDHERVLHRTTLVGDIPVGPDGRPSEPLEGQFFGAA
>NC_016947.1|WP_008261583.1|4963400_4964726_-|UDP-glucose/GDP-mannose-dehydrogenase-family-protein
MRCTVFGTGYLGATHAVGMAALGHDVLGIDIDPGKVAKLAGGDIPFYEPGLRKLLNENLAAGRLRFTTDYDAAADFADLHFLGVGTPQKKGEYGADLRHVYAVIDELVPRLTSSAVLVGKSTVPVGTAAELNQRAAALAPRGVDVEIAWNPEFLREGYAVQDTLRPDRIVLGVHQDSVRAEAAVRELYGPLLDAGVPFLVTDLQTAELVKVSANAFLATKISFINAISEVCEAAGADVSLLADALGYDPRIGRQFLNAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSINMRRRTRMVELASAACGGSLLGANVAVLGAAFKPESDDVRDSPALNVAGQLQLNGAAVNVYDPKALDNAQRLFPTLNYAVSVEEACERADAVLVLTEWRQFVELDPDDLADGVRARVIVDGRNCLDTARWQRAGWRVYRLGAPRP
>NC_016947.1|WP_179293542.1|4964822_4966238_-|hypothetical-protein
MVLVEGENGDGATVDEDNFDVTTSTDAATVTASDQVVSAILGTRQGAAEGGYQLASTGVTFTDPVEAAALRDKLAAHKVENVMLVSAFLAAAALAQAVGHRTNYAQTALLYIEPETATLAIVDSADGSIADVRRQVLPEDDEAAVAELTRLVSGAENMESRPDAVFVVGSGIDIPLIKPALEAATTLPLTAAEEPETALARGAALASAHAPLFASSTAALAYAQDPGTGAINPLAVAPGYFDAPGDAGVDALAYSAVPDDPDDFFTGSQTAATELVGAEYRGRNFKLVGSAVAAVFVIGVVALVVSLAIAIRPTANVRPSPNENVVVAPTRPAPAPAAPAPAQAPAAPAPAPEAPAPVPEAPAPAPAAPAPAPVAPAPIPVPAAPPPAPAPPPVAPVPVPIPLPIPGIGGPPGGGWGPGHGGGHGDHDDGFPGGPRGGFGGGPRGGFGGGHGHGGFGGGGPRINIPGIPGI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_016947_2	2.1\|350419\|33\|NC_016947\|CRISPRCasFinder	350419-350451	33	NC_016947.1	350362-350394	0	1.0

1. spacer 2.1|350419|33|NC_016947|CRISPRCasFinder matches to position: 350362-350394, mismatch: 0, identity: 1.0

gatccgatgggtgccgacccgcttcgcccggct	CRISPR spacer
gatccgatgggtgccgacccgcttcgcccggct	Protospacer
*********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_016947_2	2.1\|350419\|33\|NC_016947\|CRISPRCasFinder	350419-350451	33	NZ_CP011667	Streptomyces sp. Mg1 plasmid pSMg1-3, complete sequence	96870-96902	7	0.788
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1564738-1564770	7	0.788
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	248522-248554	7	0.788
NC_016947_1	1.1\|27150\|34\|NC_016947\|CRISPRCasFinder	27150-27183	34	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	555402-555435	8	0.765
NC_016947_1	1.1\|27150\|34\|NC_016947\|CRISPRCasFinder	27150-27183	34	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	549521-549554	8	0.765
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	199725-199757	8	0.758
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	KY006853	Erythrobacter phage vB_EliS_R6L, complete genome	25355-25387	8	0.758
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	NZ_CP020399	Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence	97869-97901	8	0.758
NC_016947_1	1.1\|27150\|34\|NC_016947\|CRISPRCasFinder	27150-27183	34	NZ_CP012916	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence	187854-187887	9	0.735
NC_016947_1	1.1\|27150\|34\|NC_016947\|CRISPRCasFinder	27150-27183	34	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	283810-283843	9	0.735
NC_016947_1	1.1\|27150\|34\|NC_016947\|CRISPRCasFinder	27150-27183	34	NZ_CP032341	Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence	52186-52219	9	0.735
NC_016947_1	1.1\|27150\|34\|NC_016947\|CRISPRCasFinder	27150-27183	34	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	570738-570771	9	0.735
NC_016947_1	1.1\|27150\|34\|NC_016947\|CRISPRCasFinder	27150-27183	34	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1389609-1389642	9	0.735
NC_016947_1	1.1\|27150\|34\|NC_016947\|CRISPRCasFinder	27150-27183	34	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	143016-143049	9	0.735
NC_016947_1	1.1\|27150\|34\|NC_016947\|CRISPRCasFinder	27150-27183	34	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	279122-279155	9	0.735
NC_016947_1	1.1\|27150\|34\|NC_016947\|CRISPRCasFinder	27150-27183	34	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	1561646-1561679	9	0.735
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	995516-995548	9	0.727
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	MK433260	Streptomyces phage Namo, complete genome	1865-1897	9	0.727
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	MF467949	Streptomyces phage Spectropatronm, complete genome	1865-1897	9	0.727
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	MN204500	Streptomyces phage Hoshi, complete genome	1865-1897	9	0.727
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	MT684589	Streptomyces phage Maya, complete genome	1873-1905	9	0.727
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	MN204495	Streptomyces phage CherryBlossom, complete genome	1882-1914	9	0.727
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	KX670790	Streptomyces phage Rima, complete genome	1865-1897	9	0.727
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	MN204494	Streptomyces phage Jaylociraptor, complete genome	1865-1897	9	0.727
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	MK433268	Streptomyces phage Popy, complete genome	1587-1619	9	0.727
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	MF467948	Streptomyces phage DrGrey, complete genome	1587-1619	9	0.727
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	MN586054	Streptomyces phage FrodoSwaggins, complete genome	1587-1619	9	0.727
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	MN586056	Streptomyces phage FidgetOrca, complete genome	1865-1897	9	0.727
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	MN204504	Streptomyces phage Soshi, complete genome	1587-1619	9	0.727
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	NZ_CP015867	Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence	499647-499679	9	0.727
NC_016947_5	5.1\|4159239\|33\|NC_016947\|CRISPRCasFinder	4159239-4159271	33	NZ_CP021375	Rhizobium sp. ACO-34A plasmid pRACO34Aa, complete sequence	142153-142185	10	0.697

1. spacer 2.1|350419|33|NC_016947|CRISPRCasFinder matches to NZ_CP011667 (Streptomyces sp. Mg1 plasmid pSMg1-3, complete sequence) position: , mismatch: 7, identity: 0.788

gatccgatgggtgccgacccgcttcgcccggct	CRISPR spacer
gctgccgcgggtgctgacccgcttcccccggct	Protospacer
* * * ..******.********** *******

2. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 7, identity: 0.788

---cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
ccctggc---cgcgcggcgaccggccgcgccgggcc	Protospacer
   .***   ************ ******** ***.

3. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 7, identity: 0.788

---cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
ccctggc---cgcgcggcgaccggccgcgccgggcc	Protospacer
   .***   ************ ******** ***.

4. spacer 1.1|27150|34|NC_016947|CRISPRCasFinder matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 8, identity: 0.765

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
gaactggtgcaggtagcccggctgcggcgacaca	Protospacer
* .***** * ******************.   *

5. spacer 1.1|27150|34|NC_016947|CRISPRCasFinder matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.765

gcgctggtcctggtagcccggctgcggcgggtaa-	CRISPR spacer
gaactggtgcaggtagcccggctgcgg-ggacacc	Protospacer
* .***** * **************** **..*

6. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 8, identity: 0.758

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
tgggtgacgcgcggcgacccgccgcgccgcttc	Protospacer
.** * **********************   ..

7. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to KY006853 (Erythrobacter phage vB_EliS_R6L, complete genome) position: , mismatch: 8, identity: 0.758

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
cgggggcggcgcggcgacgcaccgcgcccggca	Protospacer
***     ********** *.***********

8. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to NZ_CP020399 (Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

cggctca-cgcgcggcgacccgccgcgcccggct	CRISPR spacer
-gtttcgttgcgcggcgaccggccgcgcgcggca	Protospacer
 * .**. .*********** ******* ****

9. spacer 1.1|27150|34|NC_016947|CRISPRCasFinder matches to NZ_CP012916 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence) position: , mismatch: 9, identity: 0.735

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
gaactggtgcaggtagcccggctgcggcgacacc	Protospacer
* .***** * ******************.

10. spacer 1.1|27150|34|NC_016947|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 9, identity: 0.735

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
gaactggtgcaggtagcccggctgcggcgacacc	Protospacer
* .***** * ******************.

11. spacer 1.1|27150|34|NC_016947|CRISPRCasFinder matches to NZ_CP032341 (Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.735

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
gaactggtgcaggtagcccggctgcggcgacacc	Protospacer
* .***** * ******************.

12. spacer 1.1|27150|34|NC_016947|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.735

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
ctgatcgtcctgatcgcccggctgcggcgggagg	Protospacer
 .* * ******.* **************** ..

13. spacer 1.1|27150|34|NC_016947|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.735

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
ctgatcgtcctgatcgcccggctgcggcgggagg	Protospacer
 .* * ******.* **************** ..

14. spacer 1.1|27150|34|NC_016947|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 9, identity: 0.735

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
ctgatcgtcctgatcgcccggctgcggcgggagg	Protospacer
 .* * ******.* **************** ..

15. spacer 1.1|27150|34|NC_016947|CRISPRCasFinder matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 9, identity: 0.735

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
ctgatcgtcctgatcgcccggctgcggcgggagg	Protospacer
 .* * ******.* **************** ..

16. spacer 1.1|27150|34|NC_016947|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 9, identity: 0.735

gcgctggtcctggtagcccggctgcggcgggtaa	CRISPR spacer
ctgatcgtcctgatcgcccggctgcggcgggagg	Protospacer
 .* * ******.* **************** ..

17. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 9, identity: 0.727

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
gtgatcacgcgcggcgccgcgccgcgccagatg	Protospacer
  * ************ * ********* *..

18. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to MK433260 (Streptomyces phage Namo, complete genome) position: , mismatch: 9, identity: 0.727

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
cggctcatgggcggcgacccgccggtcaagaag	Protospacer
*******.* **************  *  *.

19. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to MF467949 (Streptomyces phage Spectropatronm, complete genome) position: , mismatch: 9, identity: 0.727

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
cggctcatgggcggcgacccgccggtcaagaag	Protospacer
*******.* **************  *  *.

20. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to MN204500 (Streptomyces phage Hoshi, complete genome) position: , mismatch: 9, identity: 0.727

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
cggctcatgggcggcgacccgccggtcaagaag	Protospacer
*******.* **************  *  *.

21. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to MT684589 (Streptomyces phage Maya, complete genome) position: , mismatch: 9, identity: 0.727

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
cggctcatgggcggcgacccgccggtcaagaag	Protospacer
*******.* **************  *  *.

22. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to MN204495 (Streptomyces phage CherryBlossom, complete genome) position: , mismatch: 9, identity: 0.727

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
cggctcatgggcggcgacccgccggtcaagaag	Protospacer
*******.* **************  *  *.

23. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to KX670790 (Streptomyces phage Rima, complete genome) position: , mismatch: 9, identity: 0.727

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
cggctcatgggcggcgacccgccggtcaagaag	Protospacer
*******.* **************  *  *.

24. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to MN204494 (Streptomyces phage Jaylociraptor, complete genome) position: , mismatch: 9, identity: 0.727

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
cggctcatgggcggcgacccgccggtcaagaag	Protospacer
*******.* **************  *  *.

25. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to MK433268 (Streptomyces phage Popy, complete genome) position: , mismatch: 9, identity: 0.727

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
cggctcatgggcggcgacccgccggtcaagaag	Protospacer
*******.* **************  *  *.

26. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to MF467948 (Streptomyces phage DrGrey, complete genome) position: , mismatch: 9, identity: 0.727

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
cggctcatgggcggcgacccgccggtcaagaag	Protospacer
*******.* **************  *  *.

27. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to MN586054 (Streptomyces phage FrodoSwaggins, complete genome) position: , mismatch: 9, identity: 0.727

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
cggctcatgggcggcgacccgccggtcaagaag	Protospacer
*******.* **************  *  *.

28. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to MN586056 (Streptomyces phage FidgetOrca, complete genome) position: , mismatch: 9, identity: 0.727

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
cggctcatgggcggcgacccgccggtcaagaag	Protospacer
*******.* **************  *  *.

29. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to MN204504 (Streptomyces phage Soshi, complete genome) position: , mismatch: 9, identity: 0.727

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
cggctcatgggcggcgacccgccggtcaagaag	Protospacer
*******.* **************  *  *.

30. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to NZ_CP015867 (Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence) position: , mismatch: 9, identity: 0.727

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
ccctccggccgcggccacccgccgcccccggct	Protospacer
*  ..*.  ****** ********* *******

31. spacer 5.1|4159239|33|NC_016947|CRISPRCasFinder matches to NZ_CP021375 (Rhizobium sp. ACO-34A plasmid pRACO34Aa, complete sequence) position: , mismatch: 10, identity: 0.697

cggctcacgcgcggcgacccgccgcgcccggct	CRISPR spacer
gatcgttcgcgcggcgacctgccgcgcgcggag	Protospacer
 . * . ************.******* ***

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 11107

Mycobacterium_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014378740.1\|2070_3270_+	DNA polymerase III subunit beta	G8I4E4	Mycobacterium_phage	8.3e-68	41.5
WP_014378741.1\|3270_4428_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_014378742.1\|4424_4988_+	DUF721 family protein	NA	NA	NA	NA
WP_009954877.1\|5245_7279_+	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	2.7e-135	43.1
WP_014378743.1\|7330_11107_+	intein-containing DNA gyrase subunit A	U5J9D0	Bacillus_phage	1.0e-50	27.2

DBSCAN-SWA_2

15121 : 21285

Bodo_saltans_virus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008262529.1\|15121_15670_+	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	7.5e-24	44.6
WP_080587904.1\|15692_16118_-	PH domain-containing protein	NA	NA	NA	NA
WP_003872098.1\|16273_16555_-	cell division protein CrgA	NA	NA	NA	NA
WP_014378748.1\|16684_17428_+	DUF881 domain-containing protein	NA	NA	NA	NA
WP_008262550.1\|17472_18159_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	3.7e-44	47.4
WP_014378749.1\|18136_20017_-	Stk1 family PASTA domain-containing Ser/Thr kinase	L7RGQ5	Acanthamoeba_polyphaga_moumouvirus	6.1e-17	35.1
WP_041297605.1\|20013_21285_-	serine/threonine protein kinase	A0A2R8FF19	Brazilian_cedratvirus	3.2e-17	28.9

DBSCAN-SWA_3

39344 : 40163

Rhodococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381561.1\|39344_40163_+	C40 family peptidase	A0A1W6DXV0	Rhodococcus_phage	5.2e-21	55.4

DBSCAN-SWA_4

50118 : 55083

Staphylococcus_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381570.1\|50118_53028_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	1.3e-212	45.1
WP_014381571.1\|53033_53705_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_009954167.1\|53763_54267_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_014381572.1\|54333_55083_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.6e-22	34.2

DBSCAN-SWA_5

66856 : 67951

Stenotrophomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008262662.1\|66856_67951_-	inositol-3-phosphate synthase	A0A0H4IPK5	Stenotrophomonas_phage	4.6e-73	42.2

DBSCAN-SWA_6

75568 : 80024

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008262692.1\|75568_76087_+	single-stranded DNA-binding protein	A0A2H4JEL4	uncultured_Caudovirales_phage	3.3e-53	86.1
WP_003874730.1\|76123_76378_+	30S ribosomal protein S18	NA	NA	NA	NA
WP_008262694.1\|76408_76867_+	50S ribosomal protein L9	NA	NA	NA	NA
WP_014381578.1\|77396_80024_+	replicative DNA helicase	O80281	Escherichia_phage	1.7e-28	34.4

DBSCAN-SWA_7

84501 : 89284

Trichoplusia_ni_ascovirus(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952110.1\|84501_84705_+	cold-shock protein	Q9AZD3	Lactococcus_phage	1.7e-13	52.3
WP_008262709.1\|85059_85689_-	hypothetical protein	NA	NA	NA	NA
WP_009952109.1\|85773_86688_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_014381582.1\|86980_87538_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_014381583.1\|87620_88391_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.3e-13	29.4
WP_009952105.1\|88540_89284_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	5.4e-09	26.2

DBSCAN-SWA_8

96032 : 97466

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952095.1\|96032_97466_+	FAD-binding oxidoreductase	S4VRT3	Pandoravirus	1.5e-23	35.3

DBSCAN-SWA_9

126161 : 127133

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014378808.1\|126161_127133_+	2-hydroxyacid dehydrogenase	A0A1B1IVB5	uncultured_Mediterranean_phage	6.0e-16	29.6

DBSCAN-SWA_10

130680 : 131499

Lake_Baikal_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014378812.1\|130680_131499_-	CbbQ/NirQ/NorQ/GpvN family protein	A0A2H4N7N3	Lake_Baikal_phage	5.0e-16	28.2

DBSCAN-SWA_11

134885 : 141319

Burkholderia_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956874.1\|134885_136214_-	MFS transporter	Q6JIH2	Burkholderia_virus	7.6e-46	28.9
WP_014378815.1\|136503_137076_-	hemerythrin domain-containing protein	NA	NA	NA	NA
WP_009956872.1\|137417_138302_+	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	1.1e-27	30.5
WP_009956871.1\|138386_138941_+	hypothetical protein	NA	NA	NA	NA
WP_014378816.1\|139011_139365_+	VOC family protein	NA	NA	NA	NA
WP_041798331.1\|139370_139637_-	YdeI/OmpD-associated family protein	NA	NA	NA	NA
WP_009956865.1\|139633_140527_-	hypothetical protein	NA	NA	NA	NA
WP_014378818.1\|140599_141319_+	CoA pyrophosphatase	E5DQL1	Aeromonas_phage	9.2e-06	37.1

DBSCAN-SWA_12

151328 : 152657

Feldmannia_species_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956853.1\|151328_152657_+	HAMP domain-containing histidine kinase	B5LWN0	Feldmannia_species_virus	3.9e-10	26.1

DBSCAN-SWA_13

158932 : 164173

Mycobacterium_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381603.1\|158932_160591_+\|protease	type VII secretion system ESX-2 serine protease mycosin MycP2	A0A0A7HDD8	Mycobacterium_phage	5.5e-70	36.2
WP_014378832.1\|160587_162210_+	type VII secretion protein EccE	NA	NA	NA	NA
WP_170320649.1\|162322_164173_+	type VII secretion system ESX-2 AAA family ATPase EccA2	V5UQM2	Mycobacterium_phage	2.3e-48	30.1

DBSCAN-SWA_14

178663 : 179878

uncultured_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014378838.1\|178663_179878_-	DNA polymerase IV	A0A218MNF2	uncultured_virus	2.1e-18	32.9

DBSCAN-SWA_15

186815 : 187439

Bacillus_thuringiensis_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007771867.1\|186815_187439_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	2.7e-38	44.1

DBSCAN-SWA_16

195916 : 197176

Orpheovirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008262975.1\|195916_197176_+\|tRNA	serine--tRNA ligase	A0A2I2L4X3	Orpheovirus	1.8e-52	33.3

DBSCAN-SWA_17

209777 : 210968

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263005.1\|209777_210968_+	UDP-galactopyranose mutase	E4ZFQ1	Streptococcus_phage	2.0e-85	43.4

DBSCAN-SWA_18

216807 : 218916

Macacine_betaherpesvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020188359.1\|216807_217851_+	esterase family protein	A0A2I6B0H1	Macacine_betaherpesvirus	8.1e-152	80.4
WP_008263024.1\|218013_218916_+	esterase family protein	A0A2I6B2Q9	Macacine_betaherpesvirus	4.1e-43	39.1

DBSCAN-SWA_19

253570 : 254368

Anomala_cuprea_entomopoxvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263074.1\|253570_254368_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	5.8e-09	23.3

DBSCAN-SWA_20

263996 : 265064

Pacmanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020188354.1\|263996_265064_-	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	1.2e-14	25.4

DBSCAN-SWA_21

269161 : 277902

Mycobacterium_phage(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263106.1\|269161_269317_+	hypothetical protein	A0A1C9EH86	Mycobacterium_phage	7.5e-06	52.9
WP_008263107.1\|269470_270175_+	two-component system response regulator TcrX	W8CYM9	Bacillus_phage	1.3e-36	36.9
WP_170320650.1\|270236_271667_+	HAMP domain-containing protein	Q8QKV7	Ectocarpus_siliculosus_virus	7.2e-10	28.1
WP_008263112.1\|271667_272159_-	lipoprotein LpqH	NA	NA	NA	NA
WP_026071066.1\|272328_274203_+	MBL fold metallo-hydrolase	A0A2P0VMX1	Tetraselmis_virus	1.7e-139	46.1
WP_014381633.1\|274210_275179_-	NADPH:quinone oxidoreductase family protein	NA	NA	NA	NA
WP_014381634.1\|275178_275802_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_014381635.1\|275782_277066_-	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_014381636.1\|277137_277902_-	glucose 1-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	2.7e-19	31.6

DBSCAN-SWA_22

282913 : 284008

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381640.1\|282913_284008_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.3e-22	35.4

DBSCAN-SWA_23

287564 : 288023

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263147.1\|287564_288023_+	nucleoside deaminase	S4VYT2	Pandoravirus	4.5e-06	37.1

DBSCAN-SWA_24

294193 : 297818

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263155.1\|294193_294679_-	NINE protein	A0A0A7RVM3	Mycobacterium_phage	1.0e-08	43.4
WP_008263157.1\|294806_295193_+	DUF2237 domain-containing protein	NA	NA	NA	NA
WP_014381648.1\|295293_296565_+	sulfotransferase	NA	NA	NA	NA
WP_014381649.1\|296579_297818_+	MBL fold metallo-hydrolase	A0A1V0SGC6	Hokovirus	2.1e-26	28.9

DBSCAN-SWA_25

312503 : 313493

Cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381656.1\|312503_313493_+	D-2-hydroxyacid dehydrogenase family protein	A0A1M7XU89	Cedratvirus	2.2e-26	32.6

DBSCAN-SWA_26

321628 : 321994

Streptomyces_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956696.1\|321628_321994_-	hypothetical protein	A0A2D1GP18	Streptomyces_phage	1.1e-15	47.7

DBSCAN-SWA_27

332620 : 333607

Cowpox_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263218.1\|332620_333607_-	SDR family NAD(P)-dependent oxidoreductase	G0XSR1	Cowpox_virus	5.7e-06	30.3

DBSCAN-SWA_28

339843 : 342989

Bacteriophage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381674.1\|339843_341667_+	DNA polymerase III subunits gamma/tau	A0A1L2BWV7	Bacteriophage	2.2e-40	31.6
WP_020188345.1\|341678_342989_-	class I SAM-dependent methyltransferase	A0A2I2L5L3	Orpheovirus	1.6e-32	32.2

DBSCAN-SWA_29

349221 : 350214

Croceibacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020188343.1\|349221_350214_+	DEDDh family exonuclease	I6R9X8	Croceibacter_phage	1.7e-10	29.5

DBSCAN-SWA_30

376122 : 376587

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263292.1\|376122_376587_+	GatB/YqeY domain-containing protein	A0A218KC79	Bacillus_phage	2.6e-09	35.6

DBSCAN-SWA_31

395084 : 398289

Tsukamurella_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263340.1\|395084_395435_+	WhiB family transcriptional regulator	A0A159B6S6	Tsukamurella_phage	1.3e-10	50.0
WP_008263342.1\|395447_396578_-	ArsA family ATPase	NA	NA	NA	NA
WP_008263344.1\|396574_397594_-	ArsA family ATPase	NA	NA	NA	NA
WP_008263345.1\|397657_397819_+	DUF4177 domain-containing protein	NA	NA	NA	NA
WP_008263347.1\|397821_398289_+	RidA family protein	M1I5B0	Acanthocystis_turfacea_Chlorella_virus	1.4e-15	33.6

DBSCAN-SWA_32

402809 : 408388

uncultured_Mediterranean_phage(50.0%)

holin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263368.1\|402809_404003_+\|protease	acid resistance serine protease MarP	A0A1B1IRH0	uncultured_Mediterranean_phage	9.9e-05	25.0
WP_008263370.1\|403995_404967_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_014381700.1\|404967_405486_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_020188338.1\|405723_406422_+	peptidase	NA	NA	NA	NA
WP_014381701.1\|406432_408388_-	acetate--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	1.8e-88	39.6

DBSCAN-SWA_33

413464 : 415084

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381702.1\|413464_415084_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.5e-13	31.4

DBSCAN-SWA_34

423266 : 431489

uncultured_Mediterranean_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381708.1\|423266_425600_-	DEAD/DEAH box helicase	A0A1B1IUF6	uncultured_Mediterranean_phage	5.5e-07	27.3
WP_007772268.1\|425859_426063_+	cold shock protein CspA	A0A1X9IGI9	Lactococcus_phage	8.9e-15	57.8
WP_008263431.1\|426223_426814_+	hypothetical protein	NA	NA	NA	NA
WP_014378962.1\|427017_429831_+	type I DNA topoisomerase	A0A2K9L5F8	Tupanvirus	9.6e-99	32.2
WP_026071046.1\|429827_431489_-	adenylate/guanylate cyclase domain-containing protein	A0A1B1IWY2	uncultured_Mediterranean_phage	9.9e-19	32.8

DBSCAN-SWA_35

434747 : 441284

Cafeteria_roenbergensis_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071045.1\|434747_435692_+	GDP-mannose 4,6-dehydratase	E3T4Y8	Cafeteria_roenbergensis_virus	1.3e-31	31.2
WP_008263443.1\|435688_436030_-	DUF2304 domain-containing protein	NA	NA	NA	NA
WP_014378965.1\|436026_436725_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_014378966.1\|436760_438011_-	hypothetical protein	NA	NA	NA	NA
WP_009953618.1\|438135_439206_+	DUF475 domain-containing protein	A0A172Q0Y5	Acinetobacter_phage	2.2e-56	40.7
WP_008263447.1\|440795_441284_-	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	1.6e-30	46.1

DBSCAN-SWA_36

444837 : 445449

Hokovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263453.1\|444837_445449_+	hypoxanthine phosphoribosyltransferase	A0A1V0SEQ1	Hokovirus	3.5e-06	25.7

DBSCAN-SWA_37

454887 : 458787

Bathycoccus_sp._RCC1105_virus(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381725.1\|454887_457320_+\|protease	ATP-dependent zinc metalloprotease FtsH	E5ESM9	Bathycoccus_sp._RCC1105_virus	2.0e-100	41.5
WP_014378981.1\|457336_457939_+	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	1.5e-46	54.1
WP_085976422.1\|457935_458787_+	dihydropteroate synthase	S4VNV0	Pandoravirus	9.2e-21	32.7

DBSCAN-SWA_38

464987 : 469830

Tupanvirus(33.33%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263500.1\|464987_466484_+\|tRNA	lysine--tRNA ligase	A0A2K9KZX5	Tupanvirus	1.9e-74	37.1
WP_008263502.1\|466611_466950_+	iron-regulated nucleoid-associated protein Lsr2	A0A2D1GPL8	Mycobacterium_phage	3.5e-16	41.5
WP_008263504.1\|467286_469830_+\|protease	ATP-dependent protease ATP-binding subunit ClpC	K4FB40	Cronobacter_phage	1.4e-128	39.6

DBSCAN-SWA_39

479958 : 481368

Catovirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071448.1\|479958_481368_+\|tRNA	cysteine--tRNA ligase	A0A1V0SAQ2	Catovirus	3.5e-41	27.1

DBSCAN-SWA_40

487790 : 488612

Pithovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381738.1\|487790_488612_-	metal ABC transporter ATP-binding protein	W5SAS9	Pithovirus	8.3e-11	26.8

DBSCAN-SWA_41

506060 : 507596

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956927.1\|506060_507596_-	fatty acid--CoA ligase family protein	Q75ZG1	Hepacivirus	3.0e-38	26.5

DBSCAN-SWA_42

517192 : 518098

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263643.1\|517192_518098_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	7.8e-10	28.2

DBSCAN-SWA_43

531329 : 532262

Ostreococcus_lucimarinus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014710858.1\|531329_532262_+	acetaldehyde dehydrogenase (acetylating)	G9E526	Ostreococcus_lucimarinus_virus	1.6e-34	32.9

DBSCAN-SWA_44

548088 : 552947

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263720.1\|548088_549741_+	acyl-CoA synthetase	A0A2H4PQM9	Staphylococcus_phage	6.0e-16	23.8
WP_014381757.1\|549771_550539_+	fructosamine kinase family protein	NA	NA	NA	NA
WP_014381758.1\|550575_551400_+	amidohydrolase	NA	NA	NA	NA
WP_008263726.1\|551396_552947_+	acetolactate synthase large subunit	E5EQ70	Micromonas_sp._RCC1109_virus	3.3e-08	32.6

DBSCAN-SWA_45

586624 : 593296

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008263800.1\|586624_587344_+	two-component system response regulator PhoP	W8CYM9	Bacillus_phage	2.8e-34	36.3
WP_014381773.1\|587384_588827_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	9.2e-21	29.5
WP_009951974.1\|588814_589219_-	HIT family protein	NA	NA	NA	NA
WP_009951973.1\|589225_589663_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_008263811.1\|589851_590979_-	NDMA-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	1.2e-28	27.6
WP_008263812.1\|591179_591719_-	hypothetical protein	NA	NA	NA	NA
WP_008263814.1\|591721_591931_-	ferredoxin	NA	NA	NA	NA
WP_014381774.1\|591943_593296_-	cytochrome P450	M1PWN0	Moumouvirus	5.6e-12	27.4

DBSCAN-SWA_46

611192 : 614218

Mollivirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379083.1\|611192_612083_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	3.4e-42	37.0
WP_009951944.1\|612079_614218_+	S9 family peptidase	A0A1V0SHT0	Klosneuvirus	8.8e-28	27.1

DBSCAN-SWA_47

624953 : 626036

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071462.1\|624953_626036_+	NAD(P)-dependent oxidoreductase	A0A0E3FNQ3	Synechococcus_phage	8.7e-08	31.5

DBSCAN-SWA_48

637476 : 638490

Mollivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009951920.1\|637476_638490_-	Dyp-type peroxidase	A0A0M5KAH8	Mollivirus	1.1e-20	33.3

DBSCAN-SWA_49

642129 : 649547

Microbacterium_phage(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085977624.1\|642129_644451_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.6e-272	63.4
WP_179293391.1\|644470_645109_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_014381784.1\|645098_646313_-	MCE family protein	NA	NA	NA	NA
WP_009955028.1\|646332_646722_+	hypothetical protein	NA	NA	NA	NA
WP_014381785.1\|646859_648386_+	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	2.3e-46	29.9
WP_009955025.1\|648452_649547_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	7.9e-57	37.9

DBSCAN-SWA_50

656654 : 662417

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379102.1\|656654_657443_+	response regulator transcription factor	W8CYM9	Bacillus_phage	9.1e-15	32.5
WP_014381789.1\|657439_658369_+	mycothiol synthase	NA	NA	NA	NA
WP_014381790.1\|658506_659658_+	phosphate ABC transporter substrate-binding protein PstS	M4QRU1	Synechococcus_phage	1.9e-21	26.7
WP_020188694.1\|659673_660717_+	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_014379105.1\|660713_661628_+	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_008263919.1\|661640_662417_+	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-16	34.0

DBSCAN-SWA_51

669865 : 673541

Streptococcus_phage(33.33%)

integrase

attL 666167:666180|attR 675327:675340

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
666167:666180	attL	NA	NA	NA	NA
WP_020188695.1\|669865_670264_-	helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	6.0e-07	30.4
WP_009954446.1\|670308_670809_-	nucleoside deaminase	S4VYZ2	Pandoravirus	7.3e-10	34.0
WP_009954445.1\|670929_671829_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_012396382.1\|672383_673541_-\|integrase	site-specific integrase	A0A0E3XBN7	Gordonia_phage	7.1e-32	30.1
675327:675340	attR	NA	NA	NA	NA

DBSCAN-SWA_52

697776 : 698601

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381808.1\|697776_698601_-	NAD(P)-dependent oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	7.3e-07	27.5

DBSCAN-SWA_53

705495 : 707366

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379137.1\|705495_705834_-	2Fe-2S iron-sulfur cluster binding domain-containing protein	A0A222YX16	Synechococcus_phage	1.1e-06	34.3
WP_009954406.1\|705959_707366_+	acyl--CoA ligase	Q75ZG1	Hepacivirus	1.2e-36	32.5

DBSCAN-SWA_54

717889 : 720336

Only_Syngen_Nebraska_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954396.1\|717889_718645_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	6.7e-15	27.1
WP_009954395.1\|718719_720336_-	FAD-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	1.8e-25	27.6

DBSCAN-SWA_55

724627 : 726355

Lactobacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381819.1\|724627_726355_+	FAD-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	1.9e-20	24.1

DBSCAN-SWA_56

729502 : 732745

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954386.1\|729502_730324_+	alpha/beta fold hydrolase	A0A249XTU1	Mycobacterium_phage	3.6e-06	26.4
WP_142305258.1\|730328_731933_-	multicopper oxidase family protein	NA	NA	NA	NA
WP_008253618.1\|732022_732745_-	SDR family oxidoreductase	A0A0G2Y8L6	Acanthamoeba_polyphaga_mimivirus	3.2e-06	32.3

DBSCAN-SWA_57

736577 : 737387

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952206.1\|736577_737387_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	5.3e-18	30.4

DBSCAN-SWA_58

790726 : 791845

Staphylococcus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_142305508.1\|790726_791845_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.1e-35	32.6

DBSCAN-SWA_59

822049 : 823453

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379214.1\|822049_823453_+	fatty acid--CoA ligase family protein	A0A1V0SBX8	Catovirus	3.0e-16	27.1

DBSCAN-SWA_60

841391 : 843041

Acidianus_filamentous_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379227.1\|841391_843041_-	DEAD/DEAH box helicase	B2CRJ8	Acidianus_filamentous_virus	2.7e-16	23.1

DBSCAN-SWA_61

847204 : 850783

Macacine_betaherpesvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381840.1\|847204_847999_-	transglycosylase family protein	A0A2I6B0Z0	Macacine_betaherpesvirus	6.6e-05	65.8
WP_009957587.1\|848428_848707_-	MoaD/ThiS family protein	NA	NA	NA	NA
WP_020188648.1\|848711_849806_-	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
WP_009957585.1\|849802_850210_-	YccF domain-containing protein	NA	NA	NA	NA
WP_008253852.1\|850375_850783_+	cold-shock protein	Q9AZD3	Lactococcus_phage	1.3e-09	46.0

DBSCAN-SWA_62

881401 : 883789

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381860.1\|881401_883789_+	cation-translocating P-type ATPase	M1HN09	Paramecium_bursaria_Chlorella_virus	2.9e-27	26.3

DBSCAN-SWA_63

906212 : 910511

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381874.1\|906212_907142_-	Ku protein	A0A249XRB2	Mycobacterium_phage	2.7e-66	50.0
WP_014381875.1\|907296_908220_-	carbohydrate kinase	NA	NA	NA	NA
WP_014381876.1\|908231_910511_+	ATP-dependent DNA ligase	A0A291AUP8	Sinorhizobium_phage	1.7e-37	35.6

DBSCAN-SWA_64

926639 : 930100

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381888.1\|926639_927692_-	M23 family metallopeptidase	A0A2D1G842	Mycobacterium_phage	9.6e-20	43.4
WP_009957827.1\|928021_929185_+	ADP-forming succinate--CoA ligase subunit beta	NA	NA	NA	NA
WP_008254012.1\|929197_930100_+	succinate--CoA ligase subunit alpha	A0A2K9L5E9	Tupanvirus	2.6e-13	31.8

DBSCAN-SWA_65

935406 : 937633

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020188656.1\|935406_936036_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.0e-20	36.0
WP_014381892.1\|936049_937633_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.4e-54	41.9

DBSCAN-SWA_66

941828 : 942677

Indivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379282.1\|941828_942677_+	aldo/keto reductase	A0A1V0SDE7	Indivirus	5.9e-36	30.7

DBSCAN-SWA_67

952455 : 956248

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254065.1\|952455_953142_+	two-component system response regulator MrpA	W8CYM9	Bacillus_phage	1.3e-36	38.7
WP_036390311.1\|953158_954721_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.6e-18	28.0
WP_020188658.1\|954793_956248_+	trypsin-like peptidase domain-containing protein	W5SAB9	Pithovirus	1.1e-05	34.1

DBSCAN-SWA_68

959409 : 960321

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254094.1\|959409_960321_+	UTP--glucose-1-phosphate uridylyltransferase	A0A127AW70	Bacillus_phage	2.6e-45	39.2

DBSCAN-SWA_69

967877 : 969176

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080588084.1\|967877_969176_+	cytochrome P450	V5UQK0	Mycobacterium_phage	7.2e-17	23.7

DBSCAN-SWA_70

973438 : 975060

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957791.1\|973438_974455_+	GHMP kinase	A0A222YW25	Synechococcus_phage	1.6e-56	39.2
WP_026071415.1\|974442_975060_+	SIS domain-containing protein	A0A067XQR2	Caulobacter_phage	1.6e-11	33.3

DBSCAN-SWA_71

980045 : 980654

Pacmanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381911.1\|980045_980654_-	alpha-ketoglutarate-dependent dioxygenase AlkB	A0A1X6WG33	Pacmanvirus	2.6e-09	30.4

DBSCAN-SWA_72

984541 : 985798

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379306.1\|984541_985798_-	aminodeoxychorismate synthase component I	S4VT78	Pandoravirus	7.9e-37	39.4

DBSCAN-SWA_73

991979 : 992774

Ostreococcus_mediterraneus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955586.1\|991979_992774_-	FkbM family methyltransferase	A0A0P0C5Z9	Ostreococcus_mediterraneus_virus	9.9e-09	34.0

DBSCAN-SWA_74

999812 : 1001510

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955595.1\|999812_1001510_+	GMC family oxidoreductase	A0A1V0S9J5	Catovirus	2.0e-06	45.3

DBSCAN-SWA_75

1010724 : 1011297

Enterobacteria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954296.1\|1010724_1011297_-	dTDP-4-dehydrorhamnose 3,5-epimerase family protein	I7HJC4	Enterobacteria_phage	3.6e-13	32.2

DBSCAN-SWA_76

1018835 : 1022536

Hokovirus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379324.1\|1018835_1020380_-\|tRNA	methionine--tRNA ligase	A0A1V0SEZ7	Hokovirus	6.2e-100	39.0
WP_026071421.1\|1020398_1021241_+	TatD family hydrolase	NA	NA	NA	NA
WP_009954283.1\|1021447_1022536_+	resuscitation-promoting factor	Q856D9	Mycobacterium_phage	2.6e-20	57.1

DBSCAN-SWA_77

1034494 : 1035820

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254208.1\|1034494_1034839_-	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	4.4e-30	57.8
WP_008254209.1\|1034839_1035820_-	ribose-phosphate diphosphokinase	A0A2H4UV84	Bodo_saltans_virus	8.1e-45	34.7

DBSCAN-SWA_78

1045720 : 1050298

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952973.1\|1045720_1047013_+	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	1.8e-132	55.9
WP_014381926.1\|1047014_1047716_+	septum formation initiator family protein	NA	NA	NA	NA
WP_009954138.1\|1047708_1048197_+	DUF501 domain-containing protein	NA	NA	NA	NA
WP_041798354.1\|1048190_1049141_+	Ppx/GppA family phosphatase	NA	NA	NA	NA
WP_009954136.1\|1049252_1049558_+	hypothetical protein	NA	NA	NA	NA
WP_009954135.1\|1049617_1050298_-	response regulator	W8CYM9	Bacillus_phage	5.8e-26	31.7

DBSCAN-SWA_79

1053812 : 1055963

Only_Syngen_Nebraska_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381930.1\|1053812_1055963_-	potassium-transporting ATPase subunit KdpB	A0A1J0FA34	Only_Syngen_Nebraska_virus	8.3e-26	24.3

DBSCAN-SWA_80

1059495 : 1060269

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954125.1\|1059495_1060269_-	response regulator transcription factor	W8CYM9	Bacillus_phage	9.5e-33	35.9

DBSCAN-SWA_81

1069178 : 1070807

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956360.1\|1069178_1070807_+	fatty acid--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	1.2e-29	23.4

DBSCAN-SWA_82

1076075 : 1079713

Moumouvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020188668.1\|1076075_1077449_-	cytochrome P450	M1PWN0	Moumouvirus	4.8e-11	26.9
WP_014381948.1\|1077598_1078237_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_014381949.1\|1078321_1078765_-	VOC family protein	NA	NA	NA	NA
WP_009951989.1\|1078876_1079713_-	glucose 1-dehydrogenase	A0A0M4JSW6	Mollivirus	6.7e-16	30.1

DBSCAN-SWA_83

1098801 : 1102232

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954593.1\|1098801_1100208_+	cystathionine beta-synthase	A0A1X9I5K7	Streptococcus_phage	1.3e-56	41.1
WP_014381960.1\|1100319_1101054_+	RDD family protein	NA	NA	NA	NA
WP_014381961.1\|1101065_1102232_+	cystathionine gamma-synthase	A0A0B5JD48	Pandoravirus	1.9e-24	33.2

DBSCAN-SWA_84

1109340 : 1117981

Flavobacterium_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254334.1\|1109340_1110129_+	isoprenyl transferase	R9W0U9	Flavobacterium_phage	1.2e-14	36.7
WP_009953457.1\|1110277_1110703_+	hypothetical protein	NA	NA	NA	NA
WP_008254336.1\|1110709_1111648_-	type I pantothenate kinase	NA	NA	NA	NA
WP_009953456.1\|1111763_1113044_+	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	1.0e-84	47.5
WP_008254339.1\|1113140_1113968_+	acyl-ACP desaturase	NA	NA	NA	NA
WP_008254341.1\|1114211_1115513_+	PhoH family protein	A0A2L0UZX2	Agrobacterium_phage	1.0e-23	31.2
WP_014381966.1\|1115601_1116477_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_014381967.1\|1116526_1117981_+	adenylate/guanylate cyclase domain-containing protein	A0A1B1IWY2	uncultured_Mediterranean_phage	3.8e-14	28.6

DBSCAN-SWA_85

1124559 : 1132110

Tupanvirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020415585.1\|1124559_1127841_+	non-ribosomal peptide synthetase	A0A2K9L3I8	Tupanvirus	2.4e-61	30.7
WP_014381971.1\|1127900_1129445_+	carboxylesterase/lipase family protein	M1PNU1	Moumouvirus	1.9e-32	34.1
WP_014381972.1\|1129441_1130542_-	NAD-dependent epimerase/dehydratase family protein	Q76TT0	Molluscum_contagiosum_virus	3.5e-28	32.1
WP_085976478.1\|1130603_1130816_-	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_014381974.1\|1130862_1132110_-	exodeoxyribonuclease VII large subunit	A0A1B3AYB4	Gordonia_phage	4.4e-72	51.5

DBSCAN-SWA_86

1139933 : 1146512

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085977620.1\|1139933_1140509_+	C40 family peptidase	A0A0K2FNG4	Mycobacterium_phage	7.9e-08	37.3
WP_009953431.1\|1140871_1141195_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_014384004.1\|1141243_1141927_-	hypothetical protein	NA	NA	NA	NA
WP_014381976.1\|1142073_1142283_+	hypothetical protein	NA	NA	NA	NA
WP_009953429.1\|1142234_1143068_-	adenylate/guanylate cyclase domain-containing protein	NA	NA	NA	NA
WP_009953427.1\|1143190_1144600_+	glucose-6-phosphate dehydrogenase	E3SJC5	Synechococcus_phage	1.2e-65	35.7
WP_009953426.1\|1144616_1145639_+	decarboxylating 6-phosphogluconate dehydrogenase	M1T2E7	Synechococcus_phage	2.9e-93	53.6
WP_008254400.1\|1145648_1146512_-	alpha/beta hydrolase	A0A0M4K6M8	Mollivirus	5.3e-08	29.8

DBSCAN-SWA_87

1150025 : 1151603

Stenotrophomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381981.1\|1150025_1151603_-	pyruvate, phosphate dikinase	A0A2D2W2B1	Stenotrophomonas_phage	4.9e-68	38.7

DBSCAN-SWA_88

1170913 : 1171774

Lake_Baikal_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379398.1\|1170913_1171774_+	CbbQ/NirQ/NorQ/GpvN family protein	A0A2H4N7N3	Lake_Baikal_phage	6.0e-12	27.5

DBSCAN-SWA_89

1196884 : 1197598

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954638.1\|1196884_1197598_-	NAD-dependent deacylase	A0A068EPD4	Bacillus_phage	9.1e-22	33.1

DBSCAN-SWA_90

1209463 : 1211083

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952352.1\|1209463_1211083_+	nitrate reductase subunit beta	A0A077SL61	Escherichia_phage	8.7e-20	46.5

DBSCAN-SWA_91

1218814 : 1221406

Mamastrovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085977621.1\|1218814_1221406_+	bifunctional FO biosynthesis protein CofGH	A9ZMK9	Mamastrovirus	4.5e-18	35.8

DBSCAN-SWA_92

1236655 : 1238607

Moumouvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071439.1\|1236655_1237351_+	adenylyl-sulfate kinase	A0A2P1ELS9	Moumouvirus	3.9e-25	40.8
WP_014379437.1\|1237347_1238607_+	sulfate adenylyltransferase	A0A2K9L4R9	Tupanvirus	3.0e-28	28.4

DBSCAN-SWA_93

1246840 : 1247800

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071442.1\|1246840_1247800_+	proline dehydrogenase family protein	A0A2H4PQT6	Staphylococcus_phage	2.3e-28	28.4

DBSCAN-SWA_94

1256502 : 1257927

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382005.1\|1256502_1257927_+	acyl-CoA synthetase	Q75ZG1	Hepacivirus	3.9e-32	32.3

DBSCAN-SWA_95

1276812 : 1282310

Staphylococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382011.1\|1276812_1277778_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.0e-20	28.0
WP_014382012.1\|1277767_1278406_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_014379463.1\|1278478_1279147_-	O-methyltransferase	NA	NA	NA	NA
WP_014382013.1\|1279348_1280104_+	RNA polymerase sigma factor SigE	A0A0F6TH34	Sinorhizobium_phage	2.1e-08	29.5
WP_020821917.1\|1280245_1280641_+	DNA-directed RNA polymerase sigma-70 factor	NA	NA	NA	NA
WP_014382014.1\|1280795_1282310_+	trypsin-like peptidase domain-containing protein	A0A1B1IRH0	uncultured_Mediterranean_phage	1.9e-08	32.2

DBSCAN-SWA_96

1291943 : 1293122

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382019.1\|1291943_1293122_+	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	3.8e-25	35.9

DBSCAN-SWA_97

1307069 : 1314103

Beihai_Nido-like_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379477.1\|1307069_1310501_-	TM0106 family RecB-like putative nuclease	A0A1L3KIW1	Beihai_Nido-like_virus	3.3e-08	25.9
WP_026071531.1\|1310561_1311143_-	LppP/LprE family lipoprotein	NA	NA	NA	NA
WP_014382022.1\|1311263_1312967_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.8e-53	34.9
WP_014382023.1\|1312963_1314103_+	acyltransferase	A0A1R3Y5Q6	Salmonella_virus	8.3e-09	25.2

DBSCAN-SWA_98

1370202 : 1371702

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379521.1\|1370202_1371702_+	long-chain fatty acid--CoA ligase	Q75ZG1	Hepacivirus	2.0e-34	30.5

DBSCAN-SWA_99

1381315 : 1382878

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953790.1\|1381315_1382878_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	3.0e-33	26.4

DBSCAN-SWA_100

1392128 : 1393646

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382032.1\|1392128_1393646_+	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	2.1e-07	25.8

DBSCAN-SWA_101

1406182 : 1407790

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379531.1\|1406182_1407790_-	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	1.2e-24	26.8

DBSCAN-SWA_102

1432323 : 1433925

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382037.1\|1432323_1433925_+	AMP-binding protein	A0A1V0SBX8	Catovirus	1.9e-11	36.7

DBSCAN-SWA_103

1440872 : 1442006

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953864.1\|1440872_1442006_-	NDMA-dependent alcohol dehydrogenase	A0A2K9L339	Tupanvirus	1.2e-15	28.8

DBSCAN-SWA_104

1464052 : 1469212

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953892.1\|1464052_1465498_+	long-chain fatty acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.8e-29	26.6
WP_020415599.1\|1465798_1466191_+	DUF732 domain-containing protein	NA	NA	NA	NA
WP_009953895.1\|1467836_1468292_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_009953897.1\|1468489_1469212_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	1.0e-20	47.4

DBSCAN-SWA_105

1473109 : 1474042

Ostreococcus_lucimarinus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953903.1\|1473109_1474042_-	acetaldehyde dehydrogenase (acetylating)	G9E526	Ostreococcus_lucimarinus_virus	2.7e-34	31.8

DBSCAN-SWA_106

1522388 : 1526255

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953968.1\|1522388_1526255_-	bifunctional diguanylate cyclase/phosphodiesterase	G3MA91	Bacillus_virus	6.9e-07	31.2

DBSCAN-SWA_107

1531044 : 1536669

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254716.1\|1531044_1532811_-	sensor domain-containing protein	M1HTZ5	Acanthocystis_turfacea_Chlorella_virus	3.7e-16	31.2
WP_009953974.1\|1532989_1534906_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.3e-50	31.4
WP_009953975.1\|1534902_1536669_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.1e-39	26.3

DBSCAN-SWA_108

1545470 : 1547306

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382057.1\|1545470_1547306_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-16	32.2

DBSCAN-SWA_109

1551517 : 1553359

Noumeavirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254752.1\|1551517_1553359_+	adenylyl-sulfate kinase	A0A1Q1PNX7	Noumeavirus	3.4e-28	25.6

DBSCAN-SWA_110

1560135 : 1574217

Mycobacterium_phage(85.71%)

transposase,integrase

attL 1556267:1556281|attR 1573944:1573958

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1556267:1556281	attL	NA	NA	NA	NA
WP_026071516.1\|1560135_1560819_-	hypothetical protein	Q9ZX60	Mycobacterium_phage	7.1e-24	44.9
WP_008254773.1\|1560994_1561318_+	hypothetical protein	NA	NA	NA	NA
WP_014382062.1\|1561532_1562666_+\|integrase	site-specific integrase	A0A249XVB5	Mycobacterium_phage	2.5e-58	39.0
WP_085977638.1\|1562814_1563977_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_014382063.1\|1564240_1564426_+	helix-turn-helix domain-containing protein	A0A2R4AP38	Mycobacterium_phage	1.5e-05	50.0
WP_014382064.1\|1564500_1564668_+	hypothetical protein	NA	NA	NA	NA
WP_014382065.1\|1564664_1565204_+	hypothetical protein	G8I4X4	Mycobacterium_virus	3.7e-23	64.1
WP_014382066.1\|1565527_1567840_+	bifunctional DNA primase/polymerase	A0A1C9EGV1	Mycobacterium_phage	2.6e-94	35.9
WP_020188789.1\|1567839_1568100_+	hypothetical protein	NA	NA	NA	NA
WP_014382068.1\|1568096_1568414_+	hypothetical protein	NA	NA	NA	NA
WP_020188788.1\|1568619_1568952_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014382069.1\|1569063_1571937_+	C40 family peptidase	G8I4C9	Mycobacterium_phage	2.2e-58	40.1
WP_014382070.1\|1571936_1572386_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014382071.1\|1572404_1573007_+	hypothetical protein	NA	NA	NA	NA
WP_014382073.1\|1573321_1573471_-	hypothetical protein	NA	NA	NA	NA
WP_014382074.1\|1573469_1573697_+	hypothetical protein	NA	NA	NA	NA
WP_080588086.1\|1573857_1574217_+	HNH endonuclease	R4JLE3	Mycobacterium_phage	9.3e-07	36.9
1573944:1573958	attR	NA	NA	NA	NA

DBSCAN-SWA_111

1590239 : 1590899

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382085.1\|1590239_1590899_+	threonylcarbamoyl-AMP synthase	S4VW33	Pandoravirus	3.3e-18	36.3

DBSCAN-SWA_112

1611566 : 1617563

Mycobacterium_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008254846.1\|1611566_1612280_-	hypothetical protein	A0A222ZL07	Mycobacterium_phage	1.5e-11	29.7
WP_008254847.1\|1612302_1612611_-	hypothetical protein	A0A1J0MBV8	Mycobacterium_phage	1.7e-17	49.0
WP_008254850.1\|1612672_1613164_-	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	9.1e-21	51.4
WP_014382091.1\|1613160_1614648_-	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_014382093.1\|1614850_1615924_+	GGDEF domain-containing protein	A0A2D0W9B6	Bordetella_phage	1.2e-09	44.7
WP_014379597.1\|1615937_1617563_-	adenylate/guanylate cyclase domain-containing protein	A0A1B1IWY2	uncultured_Mediterranean_phage	1.2e-13	30.4

DBSCAN-SWA_113

1628822 : 1632166

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071509.1\|1628822_1630862_-	ATP-dependent DNA helicase	A0A127AW80	Bacillus_phage	1.2e-50	26.9
WP_014382100.1\|1630858_1632166_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	3.1e-44	35.4

DBSCAN-SWA_114

1637435 : 1644596

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382105.1\|1637435_1638053_+	RdgB/HAM1 family non-canonical purine NTP pyrophosphatase	A0A0P0A2M4	Ugandan_cassava_brown_streak_virus	1.1e-10	33.3
WP_009952852.1\|1638221_1638572_-	DUF3817 domain-containing protein	NA	NA	NA	NA
WP_026071506.1\|1638568_1638949_-	hypothetical protein	NA	NA	NA	NA
WP_009952855.1\|1639204_1639534_+	hypothetical protein	NA	NA	NA	NA
WP_009952856.1\|1639541_1639967_-	DUF393 domain-containing protein	NA	NA	NA	NA
WP_026071504.1\|1640238_1642854_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	8.2e-28	26.8
WP_009952859.1\|1642850_1644596_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.1e-23	28.3

DBSCAN-SWA_115

1651749 : 1652499

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382106.1\|1651749_1652499_+	3-oxoacyl-ACP reductase FabG	Q06VL0	Trichoplusia_ni_ascovirus	3.2e-09	25.5

DBSCAN-SWA_116

1659257 : 1660787

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382110.1\|1659257_1660787_-	acyl--CoA ligase	Q75ZG1	Hepacivirus	6.5e-17	24.0

DBSCAN-SWA_117

1690459 : 1691467

Aureococcus_anophage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957694.1\|1690459_1691467_-	Rieske (2Fe-2S) protein	A0A076FFT9	Aureococcus_anophage	3.1e-07	25.9

DBSCAN-SWA_118

1703379 : 1704537

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957681.1\|1703379_1704537_-	Zn-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	6.2e-36	30.0

DBSCAN-SWA_119

1714467 : 1715976

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008255024.1\|1714467_1715976_-	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	7.6e-26	30.6

DBSCAN-SWA_120

1728235 : 1729801

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382135.1\|1728235_1729801_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	7.9e-18	24.4

DBSCAN-SWA_121

1737375 : 1738098

Rhodococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957520.1\|1737375_1738098_+	DUF1906 domain-containing protein	A0A2P1JXS5	Rhodococcus_phage	2.5e-51	48.4

DBSCAN-SWA_122

1761277 : 1765176

Vibrio_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008255097.1\|1761277_1761925_-	oligoribonuclease	M4M9I5	Vibrio_phage	2.7e-25	42.1
WP_014382152.1\|1763607_1765176_+	DUF853 family protein	A0A248XCZ8	Klebsiella_phage	2.3e-57	36.3

DBSCAN-SWA_123

1769270 : 1770860

Pike_perch_iridovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008255118.1\|1769270_1770860_+	acetyl-CoA carboxylase subunit beta	A0A1B2ITV7	Pike_perch_iridovirus	3.6e-18	61.1

DBSCAN-SWA_124

1784147 : 1785395

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382165.1\|1784147_1785395_+	alpha/beta hydrolase	A0A068F2G2	Mycobacterium_phage	1.5e-35	39.8

DBSCAN-SWA_125

1793621 : 1795846

Propionibacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382168.1\|1793621_1794092_+	single-stranded DNA-binding protein	A0A1D8ETH0	Propionibacterium_phage	4.6e-14	35.8
WP_009955480.1\|1794169_1795846_+	energy-dependent translational throttle protein EttA	A0A2K9L3Z8	Tupanvirus	3.4e-43	27.2

DBSCAN-SWA_126

1805150 : 1811184

Cyanophage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071535.1\|1805150_1805801_+	HNH endonuclease	H6WG01	Cyanophage	1.5e-18	34.9
WP_008255162.1\|1805868_1806096_+	hypothetical protein	NA	NA	NA	NA
WP_008255165.1\|1806082_1806550_+	DUF5130 domain-containing protein	NA	NA	NA	NA
WP_014382173.1\|1806550_1809124_-	aminopeptidase N	A0A2K9L1R3	Tupanvirus	1.3e-46	31.6
WP_008255169.1\|1809215_1809839_+	DsbA family protein	NA	NA	NA	NA
WP_014379670.1\|1809879_1810359_+	ribose-5-phosphate isomerase	NA	NA	NA	NA
WP_014382174.1\|1810377_1811184_+	Fpg/Nei family DNA glycosylase	A0A1V0CNR6	Kaumoebavirus	3.1e-10	24.9

DBSCAN-SWA_127

1814717 : 1818511

Agrobacterium_phage(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008255177.1\|1814717_1815308_+\|protease	ATP-dependent CLP protease proteolytic subunit ClpP1	A0A223W000	Agrobacterium_phage	4.7e-40	47.5
WP_008255179.1\|1815304_1815940_+\|protease	ATP-dependent CLP protease proteolytic subunit ClpP2	A0A2H4JEX1	uncultured_Caudovirales_phage	3.3e-07	31.8
WP_162471025.1\|1815962_1816871_-	homocysteine S-methyltransferase	NA	NA	NA	NA
WP_014382178.1\|1817230_1818511_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	9.3e-142	60.0

DBSCAN-SWA_128

1823796 : 1830676

Streptomyces_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071537.1\|1823796_1824351_+	transglycosylase family protein	A0A1J0GVU2	Streptomyces_phage	5.2e-25	79.7
WP_009955950.1\|1824464_1825724_+	saccharopine dehydrogenase NADP-binding domain-containing protein	NA	NA	NA	NA
WP_009955949.1\|1825782_1828431_+\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	6.0e-143	40.0
WP_009955948.1\|1828427_1829897_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_008255199.1\|1829893_1830244_+	DUF4233 domain-containing protein	NA	NA	NA	NA
WP_014382181.1\|1830265_1830676_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	4.9e-28	50.0

DBSCAN-SWA_129

1836258 : 1837362

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953574.1\|1836258_1837362_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	4.8e-54	38.2

DBSCAN-SWA_130

1847630 : 1848914

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071540.1\|1847630_1848914_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	2.9e-95	50.8

DBSCAN-SWA_131

1861305 : 1862433

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953593.1\|1861305_1862433_-	PE-PPE domain-containing protein	A0A222ZKN7	Mycobacterium_phage	1.4e-21	35.5

DBSCAN-SWA_132

1867338 : 1878363

Paenibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382190.1\|1867338_1878363_+	type I polyketide synthase	D0R7J2	Paenibacillus_phage	2.4e-28	28.2

DBSCAN-SWA_133

1892600 : 1894472

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080588092.1\|1892600_1894472_+	elongation factor 4	A0A2K9L6L3	Tupanvirus	3.1e-21	40.5

DBSCAN-SWA_134

1901454 : 1902537

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952315.1\|1901454_1902537_+	sulfate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	9.9e-28	38.4

DBSCAN-SWA_135

1916004 : 1916868

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382213.1\|1916004_1916868_+	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	2.4e-32	32.1

DBSCAN-SWA_136

1923076 : 1928166

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020188836.1\|1923076_1924630_+	GMC family oxidoreductase N-terminal domain-containing protein	A0A1V0S9M4	Catovirus	1.1e-48	29.2
WP_014382222.1\|1924959_1925109_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014382223.1\|1925372_1926992_+	OB-fold domain-containing protein	NA	NA	NA	NA
WP_009976079.1\|1927002_1928166_-	NDMA-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	5.5e-32	28.8

DBSCAN-SWA_137

1938012 : 1938816

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382231.1\|1938012_1938816_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	9.3e-07	26.2

DBSCAN-SWA_138

1975624 : 1977088

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956483.1\|1975624_1977088_-	acyl--CoA ligase	Q75ZG1	Hepacivirus	2.9e-22	23.8

DBSCAN-SWA_139

1989078 : 1990158

Acanthocystis_turfacea_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009976171.1\|1989078_1990158_+	hydroxyacid dehydrogenase	M1HUT5	Acanthocystis_turfacea_Chlorella_virus	5.1e-24	31.1

DBSCAN-SWA_140

2020569 : 2021196

Macacine_betaherpesvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956427.1\|2020569_2021196_-	hypothetical protein	A0A2I6B2H4	Macacine_betaherpesvirus	1.6e-33	45.5

DBSCAN-SWA_141

2024239 : 2025010

Niemeyer_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956424.1\|2024239_2025010_-	hypothetical protein	A0A0U2UF06	Niemeyer_virus	1.4e-23	29.2

DBSCAN-SWA_142

2046014 : 2048853

Escherichia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955698.1\|2046014_2047082_+	3-deoxy-7-phosphoheptulonate synthase	A0A060BHG3	Escherichia_phage	1.1e-82	48.1
WP_014382292.1\|2047215_2048853_-	AMP-binding protein	A0A1V0SBX8	Catovirus	1.0e-07	36.0

DBSCAN-SWA_143

2057604 : 2068616

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382296.1\|2057604_2064180_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	2.2e-125	24.4
WP_014379796.1\|2064176_2068616_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	5.3e-35	23.6

DBSCAN-SWA_144

2074836 : 2077932

Ectocarpus_siliculosus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008255583.1\|2074836_2075985_+	molecular chaperone DnaJ	Q8QNB4	Ectocarpus_siliculosus_virus	5.6e-29	30.4
WP_014382297.1\|2075998_2076760_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_026071553.1\|2076873_2077932_+	PhoH family protein	W8D063	Erwinia_phage	4.3e-44	44.3

DBSCAN-SWA_145

2086059 : 2089753

Flavobacterium_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953080.1\|2086059_2086929_+	decaprenyl diphosphate synthase	R9W0U9	Flavobacterium_phage	7.0e-16	40.5
WP_014382303.1\|2086928_2087357_+	hypothetical protein	NA	NA	NA	NA
WP_008255605.1\|2087360_2087756_-	transcriptional repressor	NA	NA	NA	NA
WP_170320583.1\|2087752_2088178_-	metalloregulator ArsR/SmtB family transcription factor	NA	NA	NA	NA
WP_008255621.1\|2088361_2089753_+\|tRNA	glycine--tRNA ligase	A0A2I2L3K8	Orpheovirus	1.7e-48	29.9

DBSCAN-SWA_146

2096129 : 2098082

Helicobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382309.1\|2096129_2098082_+	DNA primase	A0A1S5REW9	Helicobacter_phage	8.8e-35	31.7

DBSCAN-SWA_147

2103138 : 2104071

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008255646.1\|2103138_2104071_-	cysteine synthase A	A0A1X9I5K7	Streptococcus_phage	2.9e-84	53.4

DBSCAN-SWA_148

2112384 : 2119472

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379818.1\|2112384_2114337_-	acyl-CoA dehydrogenase family protein	A0A2K9L6M4	Tupanvirus	1.1e-53	30.2
WP_026071556.1\|2114386_2116723_-	ATP-binding cassette domain-containing protein	A0A2R8FG22	Brazilian_cedratvirus	5.3e-18	31.0
WP_009954612.1\|2116837_2117326_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_020188859.1\|2117489_2119472_+	ATP-binding cassette domain-containing protein	A0A2I4R674	Erysipelothrix_phage	5.7e-05	27.4

DBSCAN-SWA_149

2130607 : 2134426

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382320.1\|2130607_2131765_-	alpha/beta hydrolase	A0A1C9LYC8	Mycobacterium_phage	4.0e-43	42.2
WP_014379843.1\|2131879_2134426_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	4.4e-151	34.2

DBSCAN-SWA_150

2160351 : 2162286

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008255722.1\|2160351_2162286_+	molecular chaperone HtpG	A0A1V0SAD6	Catovirus	1.0e-107	34.3

DBSCAN-SWA_151

2165574 : 2166705

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952301.1\|2165574_2166705_-	NDMA-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	1.4e-27	28.6

DBSCAN-SWA_152

2186255 : 2187764

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952270.1\|2186255_2187764_+	ACR3 family arsenite efflux transporter	A0A2H4PQT9	Staphylococcus_phage	1.2e-10	34.7

DBSCAN-SWA_153

2196244 : 2197423

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952259.1\|2196244_2197423_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	2.0e-58	36.7

DBSCAN-SWA_154

2205247 : 2206240

Orpheovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382335.1\|2205247_2206240_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	1.5e-67	46.9

DBSCAN-SWA_155

2211911 : 2213393

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382341.1\|2211911_2213393_+	serine/threonine protein kinase	M1HUJ3	Paramecium_bursaria_Chlorella_virus	4.7e-12	28.1

DBSCAN-SWA_156

2226199 : 2233072

Oenococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020188872.1\|2226199_2226607_+	very short patch repair endonuclease	V5UTF4	Oenococcus_phage	3.3e-16	39.6
WP_014382351.1\|2226739_2228002_+	ATP-binding protein	NA	NA	NA	NA
WP_014382352.1\|2227998_2230008_-	DNA (cytosine-5-)-methyltransferase	M1PSQ0	Streptococcus_phage	7.4e-45	30.4
WP_014382353.1\|2230199_2231471_-	hypothetical protein	NA	NA	NA	NA
WP_014382354.1\|2231506_2233072_-	serine/threonine protein kinase	M1I231	Acanthocystis_turfacea_Chlorella_virus	2.1e-18	29.3

DBSCAN-SWA_157

2248076 : 2249162

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956113.1\|2248076_2249162_-	S-(hydroxymethyl)mycothiol dehydrogenase	E3SJ82	Synechococcus_phage	7.3e-31	29.5

DBSCAN-SWA_158

2279809 : 2282795

Agrobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014379931.1\|2279809_2280949_+	bifunctional RNase H/acid phosphatase	A0A2L0V0T1	Agrobacterium_phage	3.0e-06	30.8
WP_014379932.1\|2280937_2281342_-	VOC family protein	NA	NA	NA	NA
WP_014379933.1\|2281295_2282138_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_014379934.1\|2282222_2282795_-	helix-turn-helix domain-containing protein	F8TVE5	EBPR_siphovirus	9.6e-06	46.5

DBSCAN-SWA_159

2313500 : 2315048

Mycoplasma_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956001.1\|2313500_2315048_-	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	8.0e-31	33.9

DBSCAN-SWA_160

2320704 : 2326244

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008256049.1\|2320704_2321781_+	glycerate kinase	W6LM47	Streptococcus_phage	6.6e-16	29.7
WP_008256050.1\|2321860_2322217_+	iron-sulfur cluster assembly accessory protein	NA	NA	NA	NA
WP_014379954.1\|2322296_2322983_-	hypothetical protein	NA	NA	NA	NA
WP_009957664.1\|2323166_2324141_+	carbohydrate kinase family protein	NA	NA	NA	NA
WP_014379955.1\|2324285_2326244_-	asparagine synthase (glutamine-hydrolyzing)	I3UKG6	Ostreococcus_lucimarinus_virus	1.9e-21	28.3

DBSCAN-SWA_161

2335373 : 2342873

Clostridium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041798380.1\|2335373_2337305_-	DEDD exonuclease domain-containing protein	A0A0K2SUJ2	Clostridium_phage	7.5e-10	31.4
WP_170320588.1\|2337472_2337667_+	hypothetical protein	NA	NA	NA	NA
WP_026071575.1\|2337846_2338998_+	C40 family peptidase	A0A1J0GW44	Streptomyces_phage	1.1e-16	41.4
WP_008256084.1\|2339056_2339872_+	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_009953493.1\|2339927_2341058_+	GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase	NA	NA	NA	NA
WP_008256088.1\|2341070_2342873_-	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	8.1e-51	27.2

DBSCAN-SWA_162

2348682 : 2351936

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008256110.1\|2348682_2349177_+	polyadenylate-specific 3'-exoribonuclease AS	A0A249XQ39	Mycobacterium_phage	2.9e-27	43.2
WP_008256111.1\|2349251_2350640_+	3-deoxy-7-phosphoheptulonate synthase class II	NA	NA	NA	NA
WP_026071578.1\|2350646_2351936_-	protein kinase	S4W2F5	Pandoravirus	3.8e-18	35.4

DBSCAN-SWA_163

2402414 : 2403968

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382415.1\|2402414_2403968_-	long-chain fatty acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.0e-42	27.0

DBSCAN-SWA_164

2421398 : 2427067

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_017205326.1\|2421398_2423018_+	fatty acid--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	7.4e-27	25.9
WP_005086582.1\|2423056_2424202_+	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_005086581.1\|2424251_2425310_+	BtrH N-terminal domain-containing protein	NA	NA	NA	NA
WP_005110592.1\|2425401_2425812_+	SCP2 sterol-binding domain-containing protein	NA	NA	NA	NA
WP_011560572.1\|2425960_2427067_+	NDMA-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	7.2e-34	29.1

DBSCAN-SWA_165

2432585 : 2433701

Wolbachia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011560565.1\|2432585_2433701_+	patatin-like phospholipase family protein	A0A1B2LRS3	Wolbachia_phage	1.2e-15	25.4

DBSCAN-SWA_166

2454087 : 2455323

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008256229.1\|2454087_2455323_+	cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase	A0A1V0SAQ2	Catovirus	2.1e-26	25.1

DBSCAN-SWA_167

2462363 : 2481706

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_193375485.1\|2462363_2480198_+	amino acid adenylation domain-containing protein	A0A2K9KZV5	Tupanvirus	2.4e-150	27.6
WP_020188906.1\|2480197_2481706_+	MFS transporter	A0A0M3UL24	Mycobacterium_phage	1.2e-36	31.9

DBSCAN-SWA_168

2497233 : 2501028

Dickeya_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380026.1\|2497233_2501028_+	methionine synthase	A0A140XBC7	Dickeya_phage	2.6e-14	56.5

DBSCAN-SWA_169

2514515 : 2515886

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382449.1\|2514515_2515886_+	FAD-containing oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	1.3e-61	33.8

DBSCAN-SWA_170

2519014 : 2520844

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008256304.1\|2519014_2520844_+	proteasome ATPase	A0A2K9L596	Tupanvirus	2.7e-33	35.4

DBSCAN-SWA_171

2531910 : 2536482

Acanthocystis_turfacea_Chlorella_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382458.1\|2531910_2534691_+	RNA helicase	M1ILW8	Acanthocystis_turfacea_Chlorella_virus	1.2e-69	34.2
WP_008256331.1\|2534756_2535518_+	DUF4333 domain-containing protein	NA	NA	NA	NA
WP_020188912.1\|2535525_2536482_-	5'-3' exonuclease	A0A2P1JXG8	Rhodococcus_phage	4.5e-24	35.5

DBSCAN-SWA_172

2549259 : 2550015

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380045.1\|2549259_2550015_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.9e-24	32.0

DBSCAN-SWA_173

2562091 : 2576649

Sulfolobus_monocaudavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008256379.1\|2562091_2562886_+	polyprenol monophosphomannose synthase	A0A0N7A8R9	Sulfolobus_monocaudavirus	7.5e-25	39.3
WP_007770897.1\|2562895_2563231_-	RNA polymerase-binding protein RbpA	NA	NA	NA	NA
WP_026071594.1\|2563403_2563754_+	hypothetical protein	NA	NA	NA	NA
WP_041798395.1\|2564115_2576649_+	type I polyketide synthase	D0R7J2	Paenibacillus_phage	4.4e-26	31.4

DBSCAN-SWA_174

2591952 : 2592771

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071598.1\|2591952_2592771_+	mycofactocin-coupled SDR family oxidoreductase	W8CYX9	Bacillus_phage	5.4e-10	44.2

DBSCAN-SWA_175

2596283 : 2597801

Mollivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956387.1\|2596283_2597801_+	carboxylesterase/lipase family protein	A0A0M4JT58	Mollivirus	3.1e-27	31.6

DBSCAN-SWA_176

2604542 : 2605103

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071602.1\|2604542_2605103_+	pyrazinamidase PncA	A0A1V0SL12	Klosneuvirus	1.1e-06	24.2

DBSCAN-SWA_177

2610536 : 2612639

Planktothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008256437.1\|2610536_2611607_+	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	1.0e-21	30.3
WP_009956368.1\|2611673_2612639_+	patatin-like phospholipase family protein	A0A0H3TN97	Faustovirus	3.1e-17	26.7

DBSCAN-SWA_178

2631942 : 2632725

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008256510.1\|2631942_2632725_+	glucose 1-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	4.1e-15	29.7

DBSCAN-SWA_179

2643673 : 2644501

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008256524.1\|2643673_2644501_+	DUF1906 domain-containing protein	A0A1B3B0M0	Gordonia_phage	1.8e-53	46.8

DBSCAN-SWA_180

2664425 : 2665160

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020188927.1\|2664425_2665160_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.4e-22	33.7

DBSCAN-SWA_181

2674929 : 2675691

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382538.1\|2674929_2675691_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.4e-15	32.2

DBSCAN-SWA_182

2680868 : 2682368

Cyanophage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380122.1\|2680868_2682368_-	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	2.4e-72	35.8

DBSCAN-SWA_183

2685378 : 2689296

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020188934.1\|2685378_2689296_-	ATP-dependent RNA helicase HrpA	A0A1V0SIV3	Klosneuvirus	1.1e-36	24.6

DBSCAN-SWA_184

2709146 : 2709944

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380139.1\|2709146_2709944_-	DUF1906 domain-containing protein	A0A2D1GEF2	Gordonia_phage	3.7e-56	49.8

DBSCAN-SWA_185

2729732 : 2732555

Trichoplusia_ni_ascovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954866.1\|2729732_2730503_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.8e-15	32.9
WP_014380143.1\|2730510_2731188_-	hypothetical protein	NA	NA	NA	NA
WP_014382570.1\|2731322_2732555_-	EstA family serine hydrolase	A0A2K9L1U3	Tupanvirus	5.4e-30	30.6

DBSCAN-SWA_186

2753894 : 2756997

Burkholderia_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014384715.1\|2753894_2755169_+	MFS transporter	Q6JIH2	Burkholderia_virus	1.5e-14	26.6
WP_014382581.1\|2755172_2756468_-	competence/damage-inducible protein A	B5TK85	Pseudomonas_phage	6.1e-16	42.8
WP_026071388.1\|2756502_2756997_+	macro domain-containing protein	A0A0K1L687	Scale_drop_disease_virus	9.4e-10	32.6

DBSCAN-SWA_187

2765655 : 2771235

Macacine_betaherpesvirus(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382589.1\|2765655_2766669_+	alcohol dehydrogenase catalytic domain-containing protein	A0A0G2YAX3	Acanthamoeba_polyphaga_mimivirus	4.0e-31	28.6
WP_009956806.1\|2766681_2767242_+	YceI family protein	NA	NA	NA	NA
WP_026071387.1\|2767261_2768398_-	hypothetical protein	NA	NA	NA	NA
WP_009952996.1\|2769024_2770017_+	esterase family protein	A0A2I6B0H1	Macacine_betaherpesvirus	4.9e-167	86.1
WP_014382591.1\|2770161_2770692_+	chorismate mutase	NA	NA	NA	NA
WP_014382592.1\|2770824_2771235_+	transglycosylase family protein	A0A2I6B0Z0	Macacine_betaherpesvirus	8.0e-47	69.4

DBSCAN-SWA_188

2788035 : 2792167

Bodo_saltans_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953019.1\|2788035_2788473_-	DUF1810 domain-containing protein	A0A2H4UVK5	Bodo_saltans_virus	7.1e-17	40.2
WP_014382602.1\|2788492_2789752_+	alpha-hydroxy-acid oxidizing protein	NA	NA	NA	NA
WP_179293458.1\|2789845_2792167_+	endopeptidase La	A0A0R6PGP8	Moraxella_phage	1.6e-144	40.5

DBSCAN-SWA_189

2809949 : 2811053

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380167.1\|2809949_2811053_-	sulfate/molybdate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.5e-18	34.7

DBSCAN-SWA_190

2819780 : 2822726

Ostreococcus_lucimarinus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956145.1\|2819780_2821250_+	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	1.3e-33	25.7
WP_014380175.1\|2821289_2822726_+	GuaB1 family IMP dehydrogenase-related protein	A0A1V0SHK8	Klosneuvirus	1.8e-45	29.3

DBSCAN-SWA_191

2836856 : 2839682

Prochlorococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382624.1\|2836856_2839682_-	aminomethyl-transferring glycine dehydrogenase	M4QFZ1	Prochlorococcus_phage	1.9e-259	51.1

DBSCAN-SWA_192

2850340 : 2852260

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382631.1\|2850340_2852260_+	ABC transporter ATP-binding protein/permease	G3M9Y6	Bacillus_virus	1.5e-07	26.7

DBSCAN-SWA_193

2857545 : 2858262

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957627.1\|2857545_2858262_-	MgtC/SapB family protein	G3MA03	Bacillus_virus	2.5e-11	36.7

DBSCAN-SWA_194

2867962 : 2872822

Mycobacterium_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008257033.1\|2867962_2869792_-	type VII secretion system ESX-5 AAA family ATPase EccA5	V5UQM2	Mycobacterium_phage	3.7e-67	32.3
WP_009954993.1\|2869788_2870988_-	type VII secretion protein EccE	NA	NA	NA	NA
WP_014382639.1\|2871007_2872822_-\|protease	type VII secretion-associated serine protease mycosin	V5UPA7	Mycobacterium_phage	4.5e-73	35.5

DBSCAN-SWA_195

2885157 : 2889321

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954152.1\|2885157_2889321_-	type VII secretion protein EccC	V5UPA0	Mycobacterium_phage	9.2e-114	26.2

DBSCAN-SWA_196

2908361 : 2909897

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382650.1\|2908361_2909897_+	acyl-CoA synthetase	A0A2H4PQM9	Staphylococcus_phage	8.2e-28	27.3

DBSCAN-SWA_197

2916251 : 2917616

Chrysochromulina_ericina_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952433.1\|2916251_2917616_+	DEAD/DEAH box helicase	A0A0N9Q9J4	Chrysochromulina_ericina_virus	7.8e-38	28.7

DBSCAN-SWA_198

2923904 : 2924714

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071376.1\|2923904_2924714_+	SigB/SigF/SigG family RNA polymerase sigma factor	A0A0E3T5M9	Bacillus_phage	1.8e-18	30.6

DBSCAN-SWA_199

2954337 : 2955951

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952380.1\|2954337_2955951_-	acyl--CoA ligase	A0A1V0SBX8	Catovirus	3.4e-08	28.4

DBSCAN-SWA_200

2970390 : 2973087

Cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162130886.1\|2970390_2973087_-	ATP-binding cassette domain-containing protein	A0A2R8FFL6	Cedratvirus	7.9e-26	34.7

DBSCAN-SWA_201

2990807 : 2991731

Acanthamoeba_polyphaga_mimivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382691.1\|2990807_2991731_+	alpha/beta hydrolase	A0A0G2YDK2	Acanthamoeba_polyphaga_mimivirus	3.2e-35	36.9

DBSCAN-SWA_202

2996923 : 2998522

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382696.1\|2996923_2998522_+	acyl-CoA synthetase	A0A2K9KZV5	Tupanvirus	8.1e-10	26.2

DBSCAN-SWA_203

3017690 : 3019472

Acanthocystis_turfacea_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_036459107.1\|3017690_3019472_+	protein kinase	M1HKB5	Acanthocystis_turfacea_Chlorella_virus	3.4e-17	33.3

DBSCAN-SWA_204

3022815 : 3055967

Acanthamoeba_polyphaga_mimivirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_036390251.1\|3022815_3024621_-	N-acetylglutaminylglutamine amidotransferase	A0A0G2Y369	Acanthamoeba_polyphaga_mimivirus	2.8e-27	25.2
WP_014382715.1\|3024716_3055967_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	2.2e-151	27.4

DBSCAN-SWA_205

3060977 : 3061181

Lactococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382719.1\|3060977_3061181_+	cold-shock protein	Q9AZD3	Lactococcus_phage	6.8e-15	56.9

DBSCAN-SWA_206

3068745 : 3075639

uncultured_Mediterranean_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071366.1\|3068745_3069426_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	2.7e-07	27.0
WP_008257548.1\|3069569_3070388_-	segregation/condensation protein A	NA	NA	NA	NA
WP_008257550.1\|3070384_3071248_-	ParA family protein	Q8JL10	Natrialba_phage	1.5e-23	36.9
WP_014382725.1\|3071482_3072232_+	O-methyltransferase	NA	NA	NA	NA
WP_008257558.1\|3072333_3073275_-	site-specific tyrosine recombinase XerD	A0A0K2CP59	Brevibacillus_phage	6.6e-20	25.6
WP_014382726.1\|3073271_3073895_-	NUDIX hydrolase	NA	NA	NA	NA
WP_014382727.1\|3073887_3075639_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	4.7e-128	45.8

DBSCAN-SWA_207

3084183 : 3089900

Cronobacter_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382733.1\|3084183_3085446_-\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	2.6e-64	37.1
WP_014380308.1\|3087038_3087683_-	DNA-3-methyladenine glycosylase	NA	NA	NA	NA
WP_020188604.1\|3087779_3089060_+	ammonium transporter	H8ZJB2	Ostreococcus_tauri_virus	3.0e-39	31.2
WP_014382735.1\|3089135_3089900_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.0e-19	30.3

DBSCAN-SWA_208

3100841 : 3104579

Oenococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071360.1\|3100841_3101960_+	mandelate racemase	Q6A202	Oenococcus_phage	1.4e-16	24.2
WP_026071359.1\|3102051_3102738_+	ANTAR domain-containing protein	NA	NA	NA	NA
WP_014382743.1\|3102761_3104579_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2I4R674	Erysipelothrix_phage	8.0e-38	25.1

DBSCAN-SWA_209

3110352 : 3123118

Paenibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382747.1\|3110352_3116748_-	type I polyketide synthase	D0R7J2	Paenibacillus_phage	1.3e-21	29.4
WP_014380320.1\|3116728_3123118_-	type I polyketide synthase	D0R7J2	Paenibacillus_phage	4.2e-25	30.7

DBSCAN-SWA_210

3128502 : 3129705

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382749.1\|3128502_3129705_-	acetylornithine transaminase	A0A249XSK4	Mycobacterium_phage	2.5e-16	27.0

DBSCAN-SWA_211

3135408 : 3136452

Orpheovirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382754.1\|3135408_3136452_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	5.1e-29	37.9

DBSCAN-SWA_212

3141146 : 3145566

Vibrio_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071357.1\|3141146_3141752_-	translation initiation factor IF-3	A0A2I7S9Q1	Vibrio_phage	1.6e-11	34.5
WP_080588100.1\|3142257_3145566_+\|tRNA	bifunctional lysylphosphatidylglycerol synthetase/lysine--tRNA ligase LysX	A0A1V0SIS0	Klosneuvirus	7.4e-74	34.8

DBSCAN-SWA_213

3151696 : 3153067

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954195.1\|3151696_3153067_+	cytochrome P450	S4VQU1	Pandoravirus	3.8e-16	23.0

DBSCAN-SWA_214

3157195 : 3160946

uncultured_Mediterranean_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382759.1\|3157195_3160114_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	5.3e-294	53.3
WP_020188595.1\|3160247_3160946_+	MBL fold metallo-hydrolase	A0A221J762	Mycobacterium_phage	9.9e-13	69.8

DBSCAN-SWA_215

3167287 : 3176187

Bodo_saltans_virus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380346.1\|3167287_3169327_-	serine/threonine protein kinase	A0A2H4UVE2	Bodo_saltans_virus	5.1e-17	28.2
WP_193375476.1\|3169481_3172079_+	FHA domain-containing protein	A0A2R8FG22	Brazilian_cedratvirus	3.0e-30	32.8
WP_014711906.1\|3172173_3172614_+	DUF402 domain-containing protein	NA	NA	NA	NA
WP_014382762.1\|3172625_3172787_-	hypothetical protein	NA	NA	NA	NA
WP_008257666.1\|3172873_3173515_+	chemotaxis protein CheB	NA	NA	NA	NA
WP_008257667.1\|3173520_3174519_+	non-homologous end-joining DNA ligase	G8GER3	unidentified_phage	6.2e-08	29.4
WP_014382763.1\|3174518_3175409_+	non-homologous end-joining DNA ligase	NA	NA	NA	NA
WP_014380349.1\|3175401_3176187_+	Fpg/Nei family DNA glycosylase	A0A1V0CNR6	Kaumoebavirus	1.5e-09	25.4

DBSCAN-SWA_216

3181635 : 3186974

Listeria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008257678.1\|3181635_3184296_-	DNA polymerase I	A0A060AFQ3	Listeria_phage	1.2e-42	30.6
WP_014382767.1\|3184460_3184943_+	Zn-ribbon domain-containing OB-fold protein	NA	NA	NA	NA
WP_008257683.1\|3184948_3186151_+	lipid-transfer protein	NA	NA	NA	NA
WP_008257686.1\|3186359_3186974_-	ANTAR domain-containing response regulator	Q6XM27	Feldmannia_irregularis_virus	3.9e-05	31.7

DBSCAN-SWA_217

3192577 : 3194191

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_050782796.1\|3192577_3194191_+	thiol reductant ABC exporter subunit CydD	M1H3A1	Paramecium_bursaria_Chlorella_virus	4.6e-05	34.3

DBSCAN-SWA_218

3204538 : 3205357

Acinetobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008257758.1\|3204538_3205357_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	3.6e-30	36.9

DBSCAN-SWA_219

3213385 : 3214519

Faustovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382777.1\|3213385_3214519_-	histidinol-phosphate transaminase	A0A1X7QHI1	Faustovirus	2.2e-17	29.9

DBSCAN-SWA_220

3235329 : 3240637

Klosneuvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380373.1\|3235329_3236634_-	adenosylmethionine--8-amino-7-oxononanoate transaminase	A0A1V0SKB7	Klosneuvirus	6.8e-15	27.8
WP_008257820.1\|3236696_3237134_+	hypothetical protein	NA	NA	NA	NA
WP_014380374.1\|3237467_3238349_+	NlpC/P60 family peptidoglycan-binding protein RipD	A0A1J0GW44	Streptomyces_phage	4.6e-07	34.9
WP_014380375.1\|3238450_3240637_+	acyltransferase	A0A166XZF2	Gordonia_phage	1.7e-55	28.9

DBSCAN-SWA_221

3255278 : 3262571

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955515.1\|3255278_3257105_-	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	1.6e-41	23.9
WP_009955512.1\|3257205_3258078_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_009955511.1\|3258056_3258446_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_008257855.1\|3258506_3258968_+	PPOX class F420-dependent oxidoreductase	NA	NA	NA	NA
WP_008257857.1\|3259037_3262571_-	DNA polymerase III subunit alpha	Q8W6C3	Saccharomonospora_phage	0.0e+00	60.4

DBSCAN-SWA_222

3270931 : 3320169

Tupanvirus(75.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955502.1\|3270931_3274045_-\|tRNA	isoleucine--tRNA ligase	A0A2P1ELB8	Moumouvirus	9.4e-164	35.0
WP_008257871.1\|3274251_3274497_-	hypothetical protein	NA	NA	NA	NA
WP_014382785.1\|3275049_3276174_-	nitronate monooxygenase	NA	NA	NA	NA
WP_009957085.1\|3276243_3276819_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_014382786.1\|3276939_3301713_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	3.0e-143	26.2
WP_014382788.1\|3302242_3309901_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	9.0e-99	20.8
WP_014382789.1\|3309897_3320169_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	2.1e-71	24.9

DBSCAN-SWA_223

3331222 : 3340116

Ostreococcus_tauri_virus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380400.1\|3331222_3331954_-	FkbM family methyltransferase	G8DGX3	Emiliania_huxleyi_virus	7.9e-05	28.7
WP_026071341.1\|3332039_3333002_-	GDP-L-fucose synthase	D1LW79	Prochlorococcus_phage	7.6e-88	50.3
WP_014380402.1\|3333009_3334032_-	GDP-mannose 4,6-dehydratase	M1IBC3	Acanthocystis_turfacea_Chlorella_virus	1.1e-105	56.9
WP_014380403.1\|3334290_3335181_-	hypothetical protein	H8ZJG6	Ostreococcus_tauri_virus	1.1e-19	32.2
WP_026071340.1\|3335392_3336166_+	glucose-1-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_014380405.1\|3336147_3337242_+	CDP-glucose 4,6-dehydratase	J7Q7J8	Aeropyrum_coil-shaped_virus	2.6e-15	28.1
WP_014380406.1\|3337238_3337790_+	dTDP-4-dehydrorhamnose 3,5-epimerase family protein	I7HJC4	Enterobacteria_phage	1.3e-23	39.2
WP_014380407.1\|3337807_3339010_+	methyltransferase domain-containing protein	A0A1V0SJ68	Klosneuvirus	4.0e-22	27.2
WP_014380408.1\|3339006_3340116_+	DegT/DnrJ/EryC1/StrS family aminotransferase	C7U074	Ostreococcus_tauri_virus	2.4e-21	26.9

DBSCAN-SWA_224

3344112 : 3355576

Shahe_endorna-like_virus(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380414.1\|3344112_3345147_+	GDP-mannose 4,6-dehydratase	Q58M98	Prochlorococcus_phage	1.5e-70	44.1
WP_014382797.1\|3345143_3346229_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_014380416.1\|3346487_3347744_+	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	2.5e-06	37.1
WP_014380417.1\|3347751_3348531_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_026071338.1\|3348627_3349419_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_009953300.1\|3349546_3350353_-	class I SAM-dependent methyltransferase	A0A2R8FDY2	Brazilian_cedratvirus	7.6e-57	53.1
WP_080587937.1\|3350448_3351735_-	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	3.6e-08	42.9
WP_014382798.1\|3352148_3353417_-	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	4.3e-06	38.7
WP_026071337.1\|3353509_3354316_-	class I SAM-dependent methyltransferase	A0A2R8FDY2	Brazilian_cedratvirus	9.2e-55	52.6
WP_014380421.1\|3354469_3355576_-	NAD-dependent epimerase/dehydratase family protein	M1I1Z9	Acanthocystis_turfacea_Chlorella_virus	1.6e-17	24.1

DBSCAN-SWA_225

3371210 : 3383078

Hepacivirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382806.1\|3371210_3381491_+	non-ribosomal peptide synthetase	Q75ZG1	Hepacivirus	9.2e-06	23.2
WP_014380433.1\|3381596_3383078_-	HAMP domain-containing histidine kinase	A0A2K9L0Z8	Tupanvirus	1.2e-07	28.7

DBSCAN-SWA_226

3389813 : 3390581

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953266.1\|3389813_3390581_-	beta-ketoacyl-ACP reductase	Q06VL0	Trichoplusia_ni_ascovirus	5.2e-07	25.1

DBSCAN-SWA_227

3394874 : 3395609

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382811.1\|3394874_3395609_-	NlpC/P60 family peptidoglycan endopeptidase RipB	A0A0K0NL58	Gordonia_phage	3.1e-17	42.7

DBSCAN-SWA_228

3401919 : 3404791

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382816.1\|3401919_3403557_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L0W2	Tupanvirus	1.4e-33	23.5
WP_008257990.1\|3403584_3404394_-	enoyl-CoA hydratase	NA	NA	NA	NA
WP_014382817.1\|3404437_3404791_-	thioredoxin	A0A2H4P7M6	Pseudomonas_phage	6.5e-13	33.7

DBSCAN-SWA_229

3413088 : 3415677

Mycobacterium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955750.1\|3413088_3413589_-	SUF system NifU family Fe-S cluster assembly protein	A0A0K1LSF9	Mycobacterium_phage	2.2e-22	45.5
WP_014382819.1\|3413585_3414902_-	cysteine desulfurase	Q2XUY6	environmental_halophage	3.7e-101	45.8
WP_009955752.1\|3414903_3415677_-	Fe-S cluster assembly ATPase SufC	W8CYL7	Bacillus_phage	2.1e-08	28.3

DBSCAN-SWA_230

3420940 : 3421876

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382822.1\|3420940_3421876_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.5e-16	29.8

DBSCAN-SWA_231

3430027 : 3435626

Cyanophage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955768.1\|3430027_3431572_+	glucose-6-phosphate dehydrogenase	M4SIY3	Cyanophage	1.0e-73	35.2
WP_008258116.1\|3431571_3432483_+	glucose-6-phosphate dehydrogenase assembly protein OpcA	NA	NA	NA	NA
WP_009955770.1\|3432479_3433235_+	6-phosphogluconolactonase	NA	NA	NA	NA
WP_009955772.1\|3433280_3433679_+	hypothetical protein	NA	NA	NA	NA
WP_014380459.1\|3433692_3434622_+	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	4.2e-43	35.0
WP_009951912.1\|3434636_3435626_-	aldo/keto reductase	A0A1V0SKP9	Klosneuvirus	6.5e-10	25.8

DBSCAN-SWA_232

3450456 : 3453347

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380468.1\|3450456_3452076_+	bile acid CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.3e-28	28.1
WP_014380469.1\|3452075_3453347_+	alpha/beta hydrolase	A0A068F2G2	Mycobacterium_phage	6.8e-36	38.5

DBSCAN-SWA_233

3457552 : 3459537

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956168.1\|3457552_3458629_-	YvcK family protein	A1IMD5	Streptococcus_phage	3.4e-36	36.2
WP_008258167.1\|3458625_3459537_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.7e-09	34.2

DBSCAN-SWA_234

3465424 : 3471358

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008258173.1\|3465424_3465907_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.8e-13	41.4
WP_008258174.1\|3465956_3467234_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	3.3e-91	45.6
WP_014382832.1\|3467357_3467957_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	6.9e-31	41.0
WP_008258177.1\|3468075_3468783_+	LppX_LprAFG lipoprotein	NA	NA	NA	NA
WP_008258179.1\|3468779_3470336_+	MFS transporter	NA	NA	NA	NA
WP_014380478.1\|3470332_3471358_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	8.2e-40	34.7

DBSCAN-SWA_235

3479037 : 3485861

Acanthamoeba_polyphaga_mimivirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955076.1\|3479037_3480003_+	alpha/beta hydrolase	A0A2L2DMU8	Acanthamoeba_polyphaga_mimivirus	8.5e-23	31.2
WP_026071323.1\|3480049_3481537_+	NAD(P)-binding domain-containing protein	NA	NA	NA	NA
WP_009955074.1\|3481557_3482124_+	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_008258192.1\|3482199_3483411_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	8.6e-113	54.7
WP_008258194.1\|3483505_3484768_-	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	2.2e-39	33.9
WP_008258195.1\|3484789_3485116_-	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_020188564.1\|3485189_3485861_-	guanylate kinase	K4JYM5	Abalone_herpesvirus	3.2e-16	34.7

DBSCAN-SWA_236

3491562 : 3495456

Halovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020415577.1\|3491562_3492699_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	6.5e-38	31.5
WP_014380487.1\|3492695_3493211_-	hypothetical protein	NA	NA	NA	NA
WP_009951742.1\|3493207_3494500_-	dihydroorotase	NA	NA	NA	NA
WP_009951741.1\|3494496_3495456_-	aspartate carbamoyltransferase catalytic subunit	M1I6M4	Paramecium_bursaria_Chlorella_virus	2.3e-28	36.7

DBSCAN-SWA_237

3500957 : 3501707

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008258209.1\|3500957_3501707_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.0e-27	33.3

DBSCAN-SWA_238

3513814 : 3515020

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008258240.1\|3513814_3515020_-	chorismate synthase	A0A291AU41	Pandoravirus	2.0e-45	36.1

DBSCAN-SWA_239

3519325 : 3525832

Tupanvirus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955913.1\|3519325_3522040_-\|tRNA	alanine--tRNA ligase	A0A2K9L1X7	Tupanvirus	1.2e-66	35.4
WP_008258256.1\|3522171_3522561_-	YjbQ family protein	NA	NA	NA	NA
WP_014382843.1\|3522725_3523346_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_008258260.1\|3523498_3524122_+	hypothetical protein	NA	NA	NA	NA
WP_009955916.1\|3524135_3524471_-	hypothetical protein	NA	NA	NA	NA
WP_020188561.1\|3524467_3525832_-	replication-associated recombination protein A	G3MBE0	Bacillus_virus	8.0e-83	43.6

DBSCAN-SWA_240

3537536 : 3540780

Rhodococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008258283.1\|3537536_3538415_+	neutral zinc metallopeptidase	A0A1I9SA48	Rhodococcus_phage	1.6e-52	47.1
WP_009957662.1\|3538468_3539350_-	dihydrodipicolinate synthase family protein	NA	NA	NA	NA
WP_008258286.1\|3539386_3540184_-	aldolase	NA	NA	NA	NA
WP_014382849.1\|3540255_3540780_+	helix-turn-helix domain-containing protein	I3VYZ1	Thermoanaerobacterium_phage	4.4e-05	36.9

DBSCAN-SWA_241

3548790 : 3566436

Klosneuvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954372.1\|3548790_3549681_+	peptidylprolyl isomerase	A0A1V0SCU1	Indivirus	1.4e-08	34.8
WP_008258303.1\|3549694_3552073_-	RelA/SpoT family protein	NA	NA	NA	NA
WP_020188558.1\|3552208_3552751_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	1.3e-12	33.6
WP_085977604.1\|3552758_3554393_-	hypothetical protein	NA	NA	NA	NA
WP_036390139.1\|3554455_3555745_-	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	8.2e-21	30.0
WP_014382853.1\|3555749_3557576_-	protein translocase subunit SecD	NA	NA	NA	NA
WP_014382854.1\|3557688_3558015_-	preprotein translocase subunit YajC	NA	NA	NA	NA
WP_026071315.1\|3558225_3559566_+	4-aminobutyrate--2-oxoglutarate transaminase	A0A1V0SKB7	Klosneuvirus	7.0e-23	25.3
WP_014382857.1\|3559705_3563230_+	carboxylic acid reductase	A0A1V0SBX8	Catovirus	1.8e-17	22.7
WP_014382858.1\|3563293_3563986_-	hypothetical protein	NA	NA	NA	NA
WP_008258316.1\|3564115_3564502_-	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_020188556.1\|3564600_3565287_-	hypothetical protein	NA	NA	NA	NA
WP_009956162.1\|3565380_3566436_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	1.6e-06	23.9

DBSCAN-SWA_242

3569826 : 3571404

Heterosigma_akashiwo_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955060.1\|3569826_3571404_+	polyamine aminopropyltransferase	A0A1C9C533	Heterosigma_akashiwo_virus	3.3e-08	32.2

DBSCAN-SWA_243

3579275 : 3583198

Tupanvirus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953630.1\|3579275_3581351_-\|tRNA	threonine--tRNA ligase	A0A2K9L6B6	Tupanvirus	2.1e-103	36.0
WP_014382862.1\|3581449_3583198_+	cation:proton antiporter	A0A2H4J178	uncultured_Caudovirales_phage	2.4e-07	25.2

DBSCAN-SWA_244

3608031 : 3609579

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382885.1\|3608031_3609579_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	6.8e-30	26.2

DBSCAN-SWA_245

3631517 : 3632288

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020188547.1\|3631517_3632288_+	hypothetical protein	B5LJM1	Mycobacterium_phage	3.7e-13	40.5

DBSCAN-SWA_246

3656873 : 3657338

Streptomyces_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008258542.1\|3656873_3657338_-	dUTP diphosphatase	A0A2L1IVN2	Streptomyces_phage	2.0e-30	49.7

DBSCAN-SWA_247

3660990 : 3676659

Cyanophage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071295.1\|3660990_3662496_+	RNA polymerase sigma factor	M4SMP8	Cyanophage	2.6e-42	34.6
WP_009955738.1\|3662630_3663047_+	RidA family protein	NA	NA	NA	NA
WP_009955739.1\|3662992_3663364_-	DUF952 domain-containing protein	NA	NA	NA	NA
WP_008258551.1\|3663487_3663673_+	hypothetical protein	NA	NA	NA	NA
WP_009955740.1\|3663737_3664739_+	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
WP_008258553.1\|3664739_3664979_-	DUF3039 domain-containing protein	A0A059VGG3	Mycobacterium_phage	1.3e-12	46.1
WP_008258554.1\|3665049_3665496_+	DUF3099 domain-containing protein	NA	NA	NA	NA
WP_050782802.1\|3665631_3666621_+	sigma-70 family RNA polymerase sigma factor SigB	M4SMP8	Cyanophage	5.1e-39	36.9
WP_008258556.1\|3666750_3667440_+	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_014382917.1\|3667462_3668524_-	DUF4192 domain-containing protein	NA	NA	NA	NA
WP_009954997.1\|3668637_3670053_+	Si-specific NAD(P)(+) transhydrogenase	A0A2K5B2C5	Erysipelothrix_phage	5.4e-42	27.6
WP_014382918.1\|3670138_3670975_-	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_008258561.1\|3671205_3672177_+	PAC2 family protein	NA	NA	NA	NA
WP_009955001.1\|3672237_3673269_+	alpha/beta hydrolase	G1DAB1	Mycobacterium_virus	3.4e-17	29.5
WP_014382919.1\|3673314_3674001_+	PhzF family phenazine biosynthesis protein	NA	NA	NA	NA
WP_009955003.1\|3674025_3674511_-	FABP family protein	NA	NA	NA	NA
WP_008258565.1\|3674545_3675010_-	transcriptional repressor NrdR	NA	NA	NA	NA
WP_014382920.1\|3675162_3675657_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_008258568.1\|3675948_3676659_+	repressor LexA	A0A1B1P7Q3	Bacillus_phage	8.0e-10	49.2

DBSCAN-SWA_248

3689942 : 3690995

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008258595.1\|3689942_3690995_-	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	2.7e-131	73.7

DBSCAN-SWA_249

3698609 : 3701114

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_193375120.1\|3698609_3701114_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	1.8e-112	58.6

DBSCAN-SWA_250

3706074 : 3710326

Gordonia_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955239.1\|3706074_3706827_-	FAD-dependent thymidylate synthase	A0A166Y9A6	Gordonia_phage	7.1e-49	54.4
WP_014380623.1\|3706876_3708088_-	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_009955236.1\|3708140_3708875_-	cell division protein DivIVA	NA	NA	NA	NA
WP_008258621.1\|3708974_3709460_-	dihydrofolate reductase	A0A1L7N103	Ralstonia_phage	1.1e-18	39.3
WP_014380625.1\|3709525_3710326_-	thymidylate synthase	A0A1B3AY68	Gordonia_phage	6.0e-107	68.2

DBSCAN-SWA_251

3733631 : 3734951

Acanthamoeba_polyphaga_lentillevirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071285.1\|3733631_3734951_-	insulinase family protein	J3IZ03	Acanthamoeba_polyphaga_lentillevirus	7.1e-28	24.1

DBSCAN-SWA_252

3753319 : 3756091

Bodo_saltans_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041798426.1\|3753319_3756091_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	3.2e-22	23.8

DBSCAN-SWA_253

3761422 : 3763030

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071284.1\|3761422_3763030_-	MFS transporter	A0A0M3UL24	Mycobacterium_phage	1.2e-42	33.3

DBSCAN-SWA_254

3771293 : 3772673

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955394.1\|3771293_3772673_+	mycothione reductase	A0A2K5B2C5	Erysipelothrix_phage	1.3e-32	25.4

DBSCAN-SWA_255

3777577 : 3781362

Mycobacterium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382948.1\|3777577_3778537_+	PPE family protein	V5UPR1	Mycobacterium_phage	2.0e-08	31.8
WP_009955970.1\|3778508_3779288_-	3-oxoacyl-ACP reductase	A0A0M4JSW6	Mollivirus	1.6e-08	33.8
WP_014382949.1\|3779291_3780656_-	aldehyde dehydrogenase	NA	NA	NA	NA
WP_014380674.1\|3780657_3781362_-	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	A0A2P9FI75	Pseudomonas_phage	8.7e-09	47.0

DBSCAN-SWA_256

3802134 : 3802974

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952689.1\|3802134_3802974_+	SDR family oxidoreductase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	4.0e-61	46.8

DBSCAN-SWA_257

3806934 : 3808113

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382955.1\|3806934_3808113_-	phosphatidylserine decarboxylase	A0A2K9L169	Tupanvirus	1.9e-32	29.8

DBSCAN-SWA_258

3813366 : 3814263

Brevibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382960.1\|3813366_3814263_-	tyrosine recombinase XerC	A0A0K2CP59	Brevibacillus_phage	2.4e-19	26.7

DBSCAN-SWA_259

3825097 : 3825817

Phaeocystis_globosa_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382969.1\|3825097_3825817_-	ribonuclease HII	R4THQ2	Phaeocystis_globosa_virus	3.4e-08	28.4

DBSCAN-SWA_260

3831196 : 3832084

Erythrobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955186.1\|3831196_3832084_+	D-alanyl-D-alanine carboxypeptidase	A0A1P8VVG5	Erythrobacter_phage	5.3e-11	35.1

DBSCAN-SWA_261

3838484 : 3840248

Saccharomonospora_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382976.1\|3838484_3840248_+	DEAD/DEAH box helicase	I4AZM6	Saccharomonospora_phage	1.6e-88	38.4

DBSCAN-SWA_262

3847068 : 3848400

uncultured_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382983.1\|3847068_3848400_-	signal recognition particle-docking protein FtsY	D6PHS7	uncultured_phage	4.5e-14	37.1

DBSCAN-SWA_263

3853819 : 3855380

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956339.1\|3853819_3854668_-	DNA-formamidopyrimidine glycosylase	F8WPX6	Bacillus_phage	2.8e-17	25.6
WP_009956337.1\|3854672_3855380_-	ribonuclease III	A0A2K9R4Y7	Dishui_lake_phycodnavirus	8.2e-23	36.8

DBSCAN-SWA_264

3860325 : 3865412

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014382989.1\|3860325_3860808_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.0e-17	31.2
WP_014382990.1\|3861034_3861589_-	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_009955167.1\|3861599_3862232_-	vitamin K epoxide reductase family protein	NA	NA	NA	NA
WP_014382991.1\|3862228_3862996_-	DsbA family protein	NA	NA	NA	NA
WP_009955165.1\|3863091_3864210_-	alpha/beta hydrolase	M1PGN2	Moumouvirus	1.3e-30	34.6
WP_161807802.1\|3864566_3865412_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.2e-52	42.2

DBSCAN-SWA_265

3877956 : 3878640

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008258983.1\|3877956_3878640_-	uracil-DNA glycosylase	S4VZ65	Pandoravirus	1.5e-34	39.6

DBSCAN-SWA_266

3886836 : 3887484

Streptomyces_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008259006.1\|3886836_3887484_-	HU family DNA-binding protein	A0A2P1N0A2	Streptomyces_phage	6.3e-14	45.4

DBSCAN-SWA_267

3897627 : 3899214

Brazilian_cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952790.1\|3897627_3899214_-	phosphoglycerate dehydrogenase	A0A2R8FDS8	Brazilian_cedratvirus	1.4e-38	36.8

DBSCAN-SWA_268

3902900 : 3904769

Ostreococcus_lucimarinus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383012.1\|3902900_3904769_-	acetolactate synthase large subunit	A0A0P0CDR3	Ostreococcus_lucimarinus_virus	1.3e-54	28.2

DBSCAN-SWA_269

3910622 : 3911654

Micromonas_sp._RCC1109_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008259042.1\|3910622_3911654_-	6-phosphofructokinase	E5EQL4	Micromonas_sp._RCC1109_virus	6.6e-13	24.8

DBSCAN-SWA_270

3921544 : 3923626

Ralstonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383019.1\|3921544_3923626_-	NAD-dependent DNA ligase LigA	A0A0A8J9A9	Ralstonia_phage	1.9e-99	36.4

DBSCAN-SWA_271

3927398 : 3928577

Faustovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954359.1\|3927398_3928577_-	cysteine desulfurase	A0A1X7QGF3	Faustovirus	2.4e-27	25.5

DBSCAN-SWA_272

3956305 : 3957634

Bodo_saltans_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380764.1\|3956305_3957634_+	deoxyribodipyrimidine photo-lyase	A0A2H4UV63	Bodo_saltans_virus	4.4e-54	29.4

DBSCAN-SWA_273

3965359 : 3966220

Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071262.1\|3965359_3966220_-	ABC transporter ATP-binding protein	Q66093	Chlorella_virus	1.7e-06	26.0

DBSCAN-SWA_274

3970702 : 3973216

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008259160.1\|3970702_3971743_+	NAD(P)-dependent alcohol dehydrogenase	A0A2K9L7I1	Tupanvirus	1.6e-75	43.1
WP_014383026.1\|3971747_3972098_-	DUF3349 domain-containing protein	NA	NA	NA	NA
WP_009954743.1\|3972241_3973216_-	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	7.8e-157	85.3

DBSCAN-SWA_275

3977637 : 3984213

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380779.1\|3977637_3979755_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	V9VI16	Lactococcus_phage	6.5e-209	51.7
WP_008259183.1\|3979772_3980225_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A142F1R4	Bacillus_phage	5.8e-14	40.2
WP_008259184.1\|3980256_3980496_-	redoxin NrdH	V5UN81	Mycobacterium_phage	1.3e-20	63.2
WP_008259185.1\|3981024_3981579_-	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	1.2e-05	34.4
WP_014383031.1\|3981670_3982285_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_036389998.1\|3982293_3983337_+	DNA polymerase IV	F1C5A5	Cronobacter_phage	1.1e-20	28.8
WP_014383032.1\|3983271_3984213_-	SDR family oxidoreductase	W8CYX9	Bacillus_phage	1.2e-05	28.8

DBSCAN-SWA_276

3997051 : 3998578

Organic_Lake_phycodnavirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383036.1\|3997051_3998578_+	Hsp70 family protein	F2Y2E1	Organic_Lake_phycodnavirus	3.3e-21	26.0

DBSCAN-SWA_277

4018532 : 4020391

Diadromus_pulchellus_ascovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383055.1\|4018532_4019276_-	SDR family oxidoreductase	F2NZ40	Diadromus_pulchellus_ascovirus	5.4e-17	31.8
WP_014383056.1\|4019296_4020391_-	ferredoxin--NADP reductase	A0A1D7SNA5	Cyanophage	1.2e-09	41.6

DBSCAN-SWA_278

4028498 : 4028876

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954685.1\|4028498_4028876_-	Fic family protein	A0A1B3AYM0	Gordonia_phage	6.9e-21	49.2

DBSCAN-SWA_279

4037975 : 4039439

Microcystis_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955147.1\|4037975_4039439_+	YdiU family protein	A0A075BSJ0	Microcystis_phage	8.1e-49	38.4

DBSCAN-SWA_280

4049734 : 4051255

Lake_Baikal_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383067.1\|4049734_4051255_-	HAMP domain-containing protein	A0A2H4N7Z5	Lake_Baikal_phage	8.2e-20	29.3

DBSCAN-SWA_281

4055694 : 4067088

Brazilian_cedratvirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_036389977.1\|4055694_4058232_+	ATP-binding cassette domain-containing protein	A0A2R8FG22	Brazilian_cedratvirus	1.8e-27	36.6
WP_014383069.1\|4058239_4061365_-	protein kinase	M1IKX4	Paramecium_bursaria_Chlorella_virus	4.2e-10	28.4
WP_014380838.1\|4061462_4063664_-	acyltransferase	A0A166XZF2	Gordonia_phage	8.4e-74	32.2
WP_009954255.1\|4063880_4064321_+	nitroreductase family deazaflavin-dependent oxidoreductase	NA	NA	NA	NA
WP_014383070.1\|4064444_4064906_+	DUF1942 domain-containing protein	NA	NA	NA	NA
WP_020188499.1\|4065081_4065492_-	hypothetical protein	NA	NA	NA	NA
WP_014383072.1\|4065501_4067088_-	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	1.2e-13	23.3

DBSCAN-SWA_282

4082216 : 4082906

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020415574.1\|4082216_4082906_-	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	6.1e-31	37.7

DBSCAN-SWA_283

4091194 : 4091992

Niemeyer_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954275.1\|4091194_4091992_+	slipin family protein	A0A0U2UF06	Niemeyer_virus	3.7e-24	29.2

DBSCAN-SWA_284

4136217 : 4137183

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380859.1\|4136217_4137183_-	alpha/beta hydrolase	A0A1C9LZ53	Mycobacterium_phage	4.7e-05	32.7

DBSCAN-SWA_285

4140862 : 4142965

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957455.1\|4140862_4142965_+	catalase	A0A2K9L572	Tupanvirus	2.5e-144	49.4

DBSCAN-SWA_286

4156694 : 4157354

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956825.1\|4156694_4157354_-	UdgX family uracil-DNA binding protein	S5M8J1	Bacillus_phage	6.0e-12	36.5

DBSCAN-SWA_287

4161148 : 4162942

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380872.1\|4161148_4162942_-	sensor domain-containing diguanylate cyclase	A0A127AWB9	Bacillus_phage	1.1e-10	33.6

DBSCAN-SWA_288

4180266 : 4183515

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380890.1\|4180266_4183515_-	thioester reductase domain-containing protein	A0A1V0SBX8	Catovirus	4.0e-08	25.2

DBSCAN-SWA_289

4216050 : 4217604

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383146.1\|4216050_4217604_+	GMC family oxidoreductase N-terminal domain-containing protein	A0A1V0S9M4	Catovirus	1.7e-49	30.4

DBSCAN-SWA_290

4233011 : 4241705

Propionibacterium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008259632.1\|4233011_4233263_-	WhiB family transcriptional regulator	A0A173G9I6	Propionibacterium_phage	2.7e-05	50.9
WP_009955799.1\|4233667_4235767_-	ATP-dependent DNA helicase UvrD2	A0A2H4UW05	Bodo_saltans_virus	5.6e-11	22.7
WP_008259646.1\|4236041_4236296_+	mycoredoxin Mrx1	NA	NA	NA	NA
WP_008259652.1\|4236306_4237239_-	NAD(+) diphosphatase	NA	NA	NA	NA
WP_008259653.1\|4237238_4238309_-	potassium channel family protein	NA	NA	NA	NA
WP_014383157.1\|4238357_4241705_-	ATP-dependent helicase	A7KV33	Bacillus_phage	1.0e-06	20.9

DBSCAN-SWA_291

4252638 : 4257926

Diachasmimorpha_longicaudata_entomopoxvirus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014380922.1\|4252638_4254168_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	5.5e-48	32.3
WP_014383164.1\|4254184_4255411_+	lipase chaperone	NA	NA	NA	NA
WP_014381852.1\|4255943_4257044_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_009956179.1\|4257125_4257926_-	ParA family protein	Q8JL10	Natrialba_phage	1.1e-15	32.4

DBSCAN-SWA_292

4261974 : 4265368

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003874607.1\|4261974_4262229_+	transcriptional regulator WhiB1	A0A2P1N2X5	Mycobacterium_phage	1.5e-11	43.9
WP_014383168.1\|4262289_4263789_-	sensor histidine kinase	NA	NA	NA	NA
WP_007773063.1\|4263839_4264055_-	biotin/lipoyl-binding carrier protein	NA	NA	NA	NA
WP_008259700.1\|4264394_4264709_-	mycothiol system anti-sigma-R factor	NA	NA	NA	NA
WP_008259701.1\|4264705_4265368_-	sigma-70 family RNA polymerase sigma factor	A0A076YQ50	Rhizobium_phage	3.1e-08	26.5

DBSCAN-SWA_293

4269764 : 4270514

Acanthamoeba_polyphaga_mimivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383172.1\|4269764_4270514_-	SDR family oxidoreductase	A0A0G2Y924	Acanthamoeba_polyphaga_mimivirus	2.5e-06	34.3

DBSCAN-SWA_294

4297591 : 4302267

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957360.1\|4297591_4299292_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.3e-18	28.1
WP_007168097.1\|4299305_4299992_-	two-component system response regulator MtrA	W8CYM9	Bacillus_phage	1.6e-39	37.6
WP_014383184.1\|4300072_4300705_-	dTMP kinase	NA	NA	NA	NA
WP_008259773.1\|4300794_4302267_-	adenosylhomocysteinase	S4VPF6	Pandoravirus	2.0e-39	28.2

DBSCAN-SWA_295

4312767 : 4313040

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008259804.1\|4312767_4313040_-	WhiB family transcriptional regulator	A0A2P1CGA4	Mycobacterium_phage	1.9e-28	77.5

DBSCAN-SWA_296

4318069 : 4334047

Enterobacteria_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008259820.1\|4318069_4319146_-	NDP-sugar synthase	I7I009	Enterobacteria_phage	1.3e-16	26.5
WP_009955376.1\|4319147_4320038_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_009955375.1\|4320030_4320918_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	4.5e-26	35.0
WP_036389908.1\|4321043_4322516_+	LCP family protein	NA	NA	NA	NA
WP_009955373.1\|4322564_4323239_+	TIGR03089 family protein	NA	NA	NA	NA
WP_008259830.1\|4323347_4323629_+	DUF1490 family protein	NA	NA	NA	NA
WP_014383193.1\|4323637_4325854_+	manganese-exporting P-type ATPase CtpC	E4ZFI9	Streptococcus_phage	5.1e-79	32.5
WP_014383194.1\|4325860_4326511_-	cation transporter	NA	NA	NA	NA
WP_009953221.1\|4326669_4327584_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_009953222.1\|4327599_4328796_+	CoA transferase	NA	NA	NA	NA
WP_009953223.1\|4328799_4330785_-	protein kinase	A0A2R8FG94	Cedratvirus	2.2e-09	27.5
WP_026071225.1\|4330800_4331907_-	phosphate ABC transporter substrate-binding protein PstS	NA	NA	NA	NA
WP_009953225.1\|4332091_4332886_+	ATP-binding cassette domain-containing protein	A0A1V0SE00	Indivirus	3.0e-13	26.1
WP_009953226.1\|4332922_4334047_+	phosphate ABC transporter substrate-binding protein PstS	A0A1D7SRJ6	Cyanophage	4.2e-13	25.5

DBSCAN-SWA_297

4337590 : 4342356

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953232.1\|4337590_4339192_-	CHASE3 domain-containing protein	W8CYF6	Bacillus_phage	6.0e-13	25.1
WP_014383196.1\|4339188_4340334_-	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_009953234.1\|4340581_4341751_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_009953235.1\|4341834_4342356_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	8.7e-22	47.2

DBSCAN-SWA_298

4357413 : 4361321

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008259929.1\|4357413_4358202_-	RNA polymerase sigma factor SigF	A0A218KDJ1	Bacillus_phage	4.5e-14	26.5
WP_014383204.1\|4358198_4358636_-	anti-sigma factor	NA	NA	NA	NA
WP_008259932.1\|4359067_4359379_-	hypothetical protein	NA	NA	NA	NA
WP_020188468.1\|4359433_4359817_-	hypothetical protein	NA	NA	NA	NA
WP_026071220.1\|4359968_4361321_-	L-lysine 6-transaminase	A0A1V0SKB7	Klosneuvirus	1.8e-111	44.9

DBSCAN-SWA_299

4374817 : 4375948

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381004.1\|4374817_4375948_-	PPE family protein	V5UPR1	Mycobacterium_phage	4.8e-09	30.3

DBSCAN-SWA_300

4387081 : 4388665

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383216.1\|4387081_4388665_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	1.8e-57	33.3

DBSCAN-SWA_301

4397221 : 4398508

Geobacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085977598.1\|4397221_4398508_-	thymidine phosphorylase	A0A0H3UZD4	Geobacillus_virus	2.1e-77	44.1

DBSCAN-SWA_302

4406881 : 4408123

Erythrobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381024.1\|4406881_4408123_+	D-alanyl-D-alanine carboxypeptidase	A0A1P8VVG5	Erythrobacter_phage	2.4e-09	30.7

DBSCAN-SWA_303

4418053 : 4419442

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954112.1\|4418053_4419442_+	bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase	A0A0B5JD48	Pandoravirus	7.2e-15	26.5

DBSCAN-SWA_304

4426425 : 4431477

Brazilian_cedratvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041798497.1\|4426425_4429089_+	ATP-binding cassette domain-containing protein	A0A2R8FG22	Brazilian_cedratvirus	9.3e-27	35.7
WP_014383228.1\|4429125_4431477_+	ATP-binding cassette domain-containing protein	A0A2R8FFL6	Cedratvirus	1.4e-26	33.9

DBSCAN-SWA_305

4438679 : 4441967

Streptomyces_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956978.1\|4438679_4441967_-	error-prone DNA polymerase	R4TMT6	Streptomyces_phage	3.7e-118	32.3

DBSCAN-SWA_306

4446908 : 4447796

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381039.1\|4446908_4447796_-	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	1.6e-31	32.3

DBSCAN-SWA_307

4454823 : 4456434

Hokovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071205.1\|4454823_4456434_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.1e-11	26.1

DBSCAN-SWA_308

4466210 : 4467806

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014942860.1\|4466210_4467806_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	1.2e-85	38.6

DBSCAN-SWA_309

4470898 : 4471201

Mycobacterium_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952496.1\|4470898_4471201_+	WhiB family transcriptional regulator	I6XD27	Mycobacterium_virus	1.2e-10	44.2

DBSCAN-SWA_310

4477175 : 4480483

uncultured_virus(66.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383248.1\|4477175_4478792_-	chaperonin GroEL	A0A219YK78	uncultured_virus	6.7e-137	50.9
WP_007167930.1\|4478887_4479190_-	co-chaperone GroES	A0A221S3C8	uncultured_virus	5.6e-21	54.8
WP_014383249.1\|4479430_4480483_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A291ATS8	Pandoravirus	4.9e-32	35.1

DBSCAN-SWA_311

4489096 : 4490962

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952459.1\|4489096_4490962_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	M1H1Z3	Paramecium_bursaria_Chlorella_virus	9.8e-100	37.1

DBSCAN-SWA_312

4500328 : 4507746

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383257.1\|4500328_4504018_-	type VII secretion protein EccCb	V5UPA0	Mycobacterium_phage	1.4e-81	28.6
WP_009952912.1\|4504111_4505521_+	type VII secretion integral membrane protein EccD	NA	NA	NA	NA
WP_014383259.1\|4506219_4507746_+	recombinase family protein	W8EKF3	Mycobacterium_phage	1.3e-137	53.1

DBSCAN-SWA_313

4516006 : 4519858

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080588108.1\|4516006_4516621_+	hypothetical protein	A0A2D1GJZ8	Mycobacterium_phage	6.9e-26	46.6
WP_041798447.1\|4516921_4517227_+	hypothetical protein	NA	NA	NA	NA
WP_014383271.1\|4517231_4517411_+	hypothetical protein	NA	NA	NA	NA
WP_009952909.1\|4518484_4519858_-	type VII secretion protein EccB	V5UN45	Mycobacterium_phage	3.0e-29	29.9

DBSCAN-SWA_314

4526418 : 4536762

Burkholderia_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383276.1\|4526418_4528083_+	FAD-dependent oxidoreductase	G3MA85	Bacillus_virus	1.3e-34	30.2
WP_009952902.1\|4528079_4529606_+	cyclic nucleotide-binding domain-containing protein	W8CYF6	Bacillus_phage	1.3e-12	37.4
WP_009952900.1\|4529645_4530494_+	LLM class F420-dependent oxidoreductase	NA	NA	NA	NA
WP_009952899.1\|4530514_4531381_+	LLM class F420-dependent oxidoreductase	NA	NA	NA	NA
WP_008260499.1\|4531408_4532404_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	5.8e-75	46.5
WP_026071199.1\|4532405_4533023_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	7.4e-28	39.3
WP_009952896.1\|4533222_4534344_+	acyltransferase	A9YX16	Burkholderia_phage	1.3e-14	27.7
WP_009952895.1\|4534473_4535610_+	acyltransferase	A9YX16	Burkholderia_phage	2.2e-17	27.5
WP_009952894.1\|4535673_4536762_+	acyltransferase	A9YX16	Burkholderia_phage	3.5e-17	29.9

DBSCAN-SWA_315

4545454 : 4546510

Faustovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383280.1\|4545454_4546510_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	A0A1X7QHI1	Faustovirus	1.4e-10	29.8

DBSCAN-SWA_316

4549994 : 4550690

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956588.1\|4549994_4550690_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.0e-31	38.5

DBSCAN-SWA_317

4557878 : 4558424

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956578.1\|4557878_4558424_-	adenylate kinase	A0A2K9L833	Tupanvirus	1.8e-14	33.8

DBSCAN-SWA_318

4562994 : 4563975

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020188445.1\|4562994_4563975_+	3-phosphoglycerate dehydrogenase	M1HBE3	Paramecium_bursaria_Chlorella_virus	3.8e-18	28.3

DBSCAN-SWA_319

4579278 : 4580169

Microcystis_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009954380.1\|4579278_4580169_-	formylglycine-generating enzyme family protein	A0A075BSL8	Microcystis_phage	2.1e-20	31.8

DBSCAN-SWA_320

4590580 : 4592026

Acanthamoeba_castellanii_mimivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957095.1\|4590580_4592026_-	mycofactocin system GMC family oxidoreductase MftG	A0A1E1EUP9	Acanthamoeba_castellanii_mimivirus	1.9e-10	22.2

DBSCAN-SWA_321

4598955 : 4599816

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071192.1\|4598955_4599816_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.9e-50	42.1

DBSCAN-SWA_322

4605192 : 4608599

Hokovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008260847.1\|4605192_4606383_-	elongation factor Tu	A0A1V0SGC3	Hokovirus	1.4e-30	27.4
WP_014383304.1\|4606493_4608599_-	elongation factor G	E4ZFJ7	Streptococcus_phage	2.7e-61	26.5

DBSCAN-SWA_323

4617405 : 4626337

Vibrio_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957074.1\|4617405_4621356_-	DNA-directed RNA polymerase subunit beta'	A0A2I7QNZ7	Vibrio_phage	9.5e-52	26.8
WP_085977595.1\|4621400_4624919_-	DNA-directed RNA polymerase subunit beta	A0A1B1ISA9	uncultured_Mediterranean_phage	3.7e-39	22.5
WP_008260873.1\|4625326_4626337_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.4e-23	35.1

DBSCAN-SWA_324

4637606 : 4641869

Micromonas_pusilla_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020823622.1\|4637606_4638953_+	AarF/ABC1/UbiB kinase family protein	G8DDN0	Micromonas_pusilla_virus	1.1e-31	29.4
WP_008260899.1\|4638955_4639861_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_008260900.1\|4639949_4640810_+	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	3.4e-23	28.4
WP_008260901.1\|4640972_4641869_+	class I SAM-dependent methyltransferase	A0A2I2L5L3	Orpheovirus	1.2e-23	29.2

DBSCAN-SWA_325

4654619 : 4657427

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957398.1\|4654619_4655624_-	patatin-like phospholipase family protein	A0A2K9KZN5	Tupanvirus	3.1e-07	24.1
WP_009957399.1\|4655624_4656092_-	cyanase	NA	NA	NA	NA
WP_009957402.1\|4656113_4656863_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_009957403.1\|4656911_4657427_-	nitroreductase family protein	A0A1V0E011	Clostridioides_phage	3.4e-10	27.0

DBSCAN-SWA_326

4661793 : 4666814

Cafeteria_roenbergensis_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383318.1\|4661793_4665096_+	exodeoxyribonuclease V subunit beta	E3T5J8	Cafeteria_roenbergensis_virus	1.3e-06	19.6
WP_014383319.1\|4665092_4666814_+	exodeoxyribonuclease V subunit alpha	A0A0K2FLP8	Brevibacillus_phage	3.1e-15	24.2

DBSCAN-SWA_327

4684925 : 4689546

Mycobacterium_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381173.1\|4684925_4685798_-	alpha/beta fold hydrolase	G1DB77	Mycobacterium_phage	7.7e-15	29.3
WP_014381174.1\|4685864_4686764_+	NYN domain-containing protein	NA	NA	NA	NA
WP_026071188.1\|4686917_4688147_+	cytochrome P450	NA	NA	NA	NA
WP_142305508.1\|4688427_4689546_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.1e-35	32.6

DBSCAN-SWA_328

4732352 : 4733381

Bodo_saltans_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383335.1\|4732352_4733381_-	NAD-dependent epimerase/dehydratase family protein	A0A2H4UUK0	Bodo_saltans_virus	1.2e-19	27.2

DBSCAN-SWA_329

4747191 : 4755696

Catovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381207.1\|4747191_4750758_+	thioester reductase domain-containing protein	A0A1V0SBX8	Catovirus	8.6e-12	24.5
WP_014381208.1\|4750780_4752139_-	amino acid permease	NA	NA	NA	NA
WP_014383341.1\|4752219_4752816_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_014383342.1\|4752938_4754303_+	AarF/ABC1/UbiB kinase family protein	A0A2P0VMP1	Tetraselmis_virus	1.2e-06	26.1
WP_014383343.1\|4754331_4755696_+	AarF/ABC1/UbiB kinase family protein	A0A2N9QVT9	Dishui_lake_phycodnavirus	7.3e-20	27.9

DBSCAN-SWA_330

4760650 : 4762774

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383347.1\|4760650_4762774_+	acyltransferase	A0A166XZF2	Gordonia_phage	8.1e-74	32.4

DBSCAN-SWA_331

4767134 : 4768373

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381214.1\|4767134_4768373_-	acyltransferase	A0A2H4JA46	uncultured_Caudovirales_phage	1.4e-14	26.7

DBSCAN-SWA_332

4781543 : 4782470

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261174.1\|4781543_4782470_+	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	4.3e-24	30.1

DBSCAN-SWA_333

4791075 : 4793132

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261205.1\|4791075_4791759_-	two-component sensory transduction protein RegX	W8CYM9	Bacillus_phage	3.4e-42	40.4
WP_008261206.1\|4791902_4793132_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	1.9e-27	33.0

DBSCAN-SWA_334

4808466 : 4810254

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020188426.1\|4808466_4809333_+	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	1.3e-30	32.4
WP_009953526.1\|4809393_4810254_-	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	6.9e-32	33.5

DBSCAN-SWA_335

4816305 : 4817703

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383364.1\|4816305_4817703_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	2.7e-46	28.4

DBSCAN-SWA_336

4820834 : 4826541

Klosneuvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071172.1\|4820834_4822907_+	S9 family peptidase	A0A1V0SHT0	Klosneuvirus	1.8e-30	30.8
WP_008261279.1\|4822917_4823229_+	hypothetical protein	NA	NA	NA	NA
WP_008261283.1\|4823236_4824148_+	crotonase/enoyl-CoA hydratase family protein	NA	NA	NA	NA
WP_014383367.1\|4824227_4824680_+	DUF5078 domain-containing protein	NA	NA	NA	NA
WP_009953519.1\|4824928_4825576_+	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.9e-34	41.1
WP_020188425.1\|4825572_4826541_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A0N7CCA3	Skermania_phage	3.3e-131	73.2

DBSCAN-SWA_337

4839119 : 4840745

uncultured_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261313.1\|4839119_4840745_-	chaperonin GroEL	A0A240F779	uncultured_virus	6.0e-154	55.7

DBSCAN-SWA_338

4849055 : 4851227

Phaeocystis_globosa_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071168.1\|4849055_4851227_+	AAA family ATPase	R4TQL5	Phaeocystis_globosa_virus	1.8e-36	40.1

DBSCAN-SWA_339

4860055 : 4860364

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261362.1\|4860055_4860364_-	DUF3263 domain-containing protein	A0A1B3AZ99	Gordonia_phage	4.2e-08	44.9

DBSCAN-SWA_340

4863483 : 4867923

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952575.1\|4863483_4867923_+	cation-translocating P-type ATPase	M1HBF8	Paramecium_bursaria_Chlorella_virus	6.0e-39	27.8

DBSCAN-SWA_341

4875609 : 4877028

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383380.1\|4875609_4877028_+	serine hydrolase	A0A2P1JQM9	Mycobacterium_phage	2.6e-12	27.4

DBSCAN-SWA_342

4880662 : 4884030

Lactobacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383385.1\|4880662_4881883_+	peptidoglycan DD-metalloendopeptidase family protein	O03937	Lactobacillus_phage	1.5e-11	30.2
WP_014383386.1\|4881866_4882907_-	hypothetical protein	NA	NA	NA	NA
WP_014383387.1\|4883046_4884030_-	NAD-dependent epimerase/dehydratase family protein	A0A2K9L4U8	Tupanvirus	7.9e-32	30.4

DBSCAN-SWA_343

4889474 : 4890242

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383393.1\|4889474_4890242_-	SGNH/GDSL hydrolase family protein	A0A160DD06	Gordonia_phage	1.6e-08	30.3

DBSCAN-SWA_344

4896162 : 4899721

Myeloproliferative_sarcoma_virus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085977591.1\|4896162_4898400_+	protein kinase	Q83745	Myeloproliferative_sarcoma_virus	2.5e-09	28.2
WP_142305508.1\|4898602_4899721_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.1e-35	32.6

DBSCAN-SWA_345

4918535 : 4919834

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956036.1\|4918535_4919834_-	adenylosuccinate synthase	A0A291AUF9	Pandoravirus	3.8e-66	34.4

DBSCAN-SWA_346

4931371 : 4931911

Prochlorococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261506.1\|4931371_4931911_-	orotate phosphoribosyltransferase	Q58MW1	Prochlorococcus_phage	2.5e-16	44.4

DBSCAN-SWA_347

4935090 : 4937637

Cronobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261516.1\|4935090_4937637_-	ATP-dependent chaperone ClpB	K4FB40	Cronobacter_phage	7.5e-119	35.6

DBSCAN-SWA_348

4940875 : 4944601

Yellowstone_lake_phycodnavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261532.1\|4940875_4942054_-	molecular chaperone DnaJ	A0A0P0YMJ9	Yellowstone_lake_phycodnavirus	3.0e-14	27.4
WP_009954032.1\|4942103_4942745_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_009954031.1\|4942741_4944601_-	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	1.1e-143	50.3

DBSCAN-SWA_349

4958428 : 4964726

Escherichia_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261569.1\|4958428_4959304_-	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	4.6e-92	56.4
WP_009954015.1\|4959327_4959702_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_009954014.1\|4959731_4960487_-	maleylpyruvate isomerase family mycothiol-dependent enzyme	NA	NA	NA	NA
WP_009954013.1\|4960587_4961244_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_009954012.1\|4961483_4962806_+	MHS family MFS transporter	Q6JIH2	Burkholderia_virus	4.1e-44	32.2
WP_080552513.1\|4962824_4963289_-	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_008261583.1\|4963400_4964726_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	1.7e-69	36.3

DBSCAN-SWA_350

4969987 : 4971225

Saccharomonospora_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261591.1\|4969987_4970560_-	dCTP deaminase	I4AZP2	Saccharomonospora_phage	2.2e-79	76.9
WP_026071149.1\|4970589_4971225_-	hypothetical protein	Q9ZX60	Mycobacterium_phage	1.8e-21	45.9

DBSCAN-SWA_351

4985220 : 4986048

Acanthocystis_turfacea_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956078.1\|4985220_4986048_-	glycoside hydrolase family 16 protein	M1I0P8	Acanthocystis_turfacea_Chlorella_virus	3.5e-09	33.3

DBSCAN-SWA_352

5002088 : 5003498

Mycobacterium_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955673.1\|5002088_5003498_-\|protease	type VII secretion-associated serine protease mycosin	V5UPA7	Mycobacterium_phage	4.5e-73	40.1

DBSCAN-SWA_353

5008416 : 5015851

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381364.1\|5008416_5012406_-	type VII secretion protein EccC	V5UPA0	Mycobacterium_phage	2.8e-96	26.7
WP_009952519.1\|5012402_5014022_-	type VII secretion protein EccB	NA	NA	NA	NA
WP_085977588.1\|5014018_5015851_-	type VII secretion system ESX-3 AAA family ATPase EccA3	V5UQM2	Mycobacterium_phage	7.9e-102	41.8

DBSCAN-SWA_354

5033542 : 5035231

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071139.1\|5033542_5035231_-	acyl-CoA synthetase	A0A2H4PQM9	Staphylococcus_phage	3.2e-25	28.7

DBSCAN-SWA_355

5050934 : 5052878

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381385.1\|5050934_5052878_+	fumarate reductase/succinate dehydrogenase flavoprotein subunit	M1HTN0	Paramecium_bursaria_Chlorella_virus	7.7e-23	27.4

DBSCAN-SWA_356

5076921 : 5078292

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381399.1\|5076921_5078292_+	PPE family protein	V5UPR1	Mycobacterium_phage	2.7e-06	33.3

DBSCAN-SWA_357

5083914 : 5088006

Yellowstone_lake_phycodnavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957646.1\|5083914_5085561_-	acetolactate synthase large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	2.8e-34	24.8
WP_026071133.1\|5085641_5087060_+	NADP-dependent succinic semialdehyde dehydrogenase	NA	NA	NA	NA
WP_009957644.1\|5087064_5088006_-	R2-like ligand-binding oxidase	A0A1V0CNG9	Kaumoebavirus	1.9e-06	27.3

DBSCAN-SWA_358

5102258 : 5103488

Cronobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381411.1\|5102258_5103488_-	TerC family protein	K4F9T9	Cronobacter_phage	2.8e-34	33.8

DBSCAN-SWA_359

5107341 : 5108859

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008261848.1\|5107341_5108859_-	long-chain fatty acid--CoA ligase	Q75ZG1	Hepacivirus	1.1e-32	29.7

DBSCAN-SWA_360

5112622 : 5115615

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383457.1\|5112622_5113828_-	alpha/beta hydrolase	A0A088FQA2	Mycobacterium_phage	7.3e-48	39.3
WP_009956936.1\|5113996_5114659_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_014383458.1\|5114886_5115615_-	alpha/beta fold hydrolase	A0A1D8EUH4	Mycobacterium_phage	1.2e-05	36.0

DBSCAN-SWA_361

5143484 : 5145473

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009952664.1\|5143484_5145473_+	M13 family metallopeptidase	A0A1V0SHG2	Klosneuvirus	2.3e-86	29.5

DBSCAN-SWA_362

5154695 : 5155352

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383473.1\|5154695_5155352_-	O-methyltransferase	S5YRC3	Mycobacterium_phage	4.4e-47	51.9

DBSCAN-SWA_363

5181894 : 5186564

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957279.1\|5181894_5183481_-	long-chain-fatty-acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	3.6e-34	28.7
WP_179300695.1\|5183675_5184356_+	FCD domain-containing protein	NA	NA	NA	NA
WP_008261971.1\|5184460_5184901_-	SRPBCC family protein	NA	NA	NA	NA
WP_044059224.1\|5184960_5185437_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_009957284.1\|5185451_5186564_+	alcohol dehydrogenase catalytic domain-containing protein	A0A0K0KVL7	Prochlorococcus_phage	2.9e-30	29.3

DBSCAN-SWA_364

5204879 : 5205623

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956630.1\|5204879_5205623_-	glucose 1-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	7.8e-16	31.6

DBSCAN-SWA_365

5227740 : 5229066

Cotesia_sesamiae_Mombasa_bracovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956657.1\|5227740_5229066_-	cytochrome P450	I6WI04	Cotesia_sesamiae_Mombasa_bracovirus	4.6e-19	22.9

DBSCAN-SWA_366

5245877 : 5248809

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009956680.1\|5245877_5246717_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	5.2e-16	25.6
WP_008262137.1\|5246706_5247525_+	ABC transporter permease	NA	NA	NA	NA
WP_008262140.1\|5247759_5248809_+	esterase family protein	A0A2I6B0H1	Macacine_betaherpesvirus	5.5e-124	67.0

DBSCAN-SWA_367

5258691 : 5266102

Yellowstone_lake_phycodnavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957107.1\|5258691_5260428_+	oxalyl-CoA decarboxylase	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	3.3e-25	25.7
WP_009957108.1\|5260411_5261341_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_009957109.1\|5261669_5262425_+	L,D-transpeptidase	NA	NA	NA	NA
WP_020188392.1\|5262535_5266102_+	thioester reductase domain-containing protein	A0A1V0SBX8	Catovirus	1.2e-10	24.2

DBSCAN-SWA_368

5271203 : 5276603

Gordonia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009957116.1\|5271203_5273198_-	acyltransferase family protein	A0A166XZF2	Gordonia_phage	9.0e-43	37.7
WP_009957119.1\|5273431_5274862_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_009957120.1\|5274890_5276603_-	thiamine pyrophosphate-binding protein	G9E525	Ostreococcus_lucimarinus_virus	1.9e-12	23.5

DBSCAN-SWA_369

5287845 : 5290532

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383501.1\|5287845_5289375_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	4.5e-34	26.6
WP_014383502.1\|5289389_5290532_+	NDMA-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	4.5e-31	28.0

DBSCAN-SWA_370

5299529 : 5301101

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383506.1\|5299529_5301101_-	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	2.2e-28	25.2

DBSCAN-SWA_371

5330542 : 5332813

uncultured_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383528.1\|5330542_5332813_+	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	3.1e-92	37.7

DBSCAN-SWA_372

5340021 : 5341653

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383534.1\|5340021_5341653_+	AMP-binding protein	A0A1V0SBX8	Catovirus	3.6e-05	21.2

DBSCAN-SWA_373

5357910 : 5358804

Prochlorococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009953137.1\|5357910_5358804_-	fructose bisphosphate aldolase	A0A0K0KVJ8	Prochlorococcus_phage	1.9e-08	29.6

DBSCAN-SWA_374

5377357 : 5379684

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014381539.1\|5377357_5378845_-	type VII secretion protein EccB	V5UN45	Mycobacterium_phage	4.5e-71	36.7
WP_020188384.1\|5378847_5379684_-	transglycosylase	A0A1L2JY60	Aeribacillus_phage	1.8e-13	42.7

DBSCAN-SWA_375

5387674 : 5389117

Mycobacterium_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383551.1\|5387674_5389117_-\|tRNA	CCA tRNA nucleotidyltransferase	A0A249XS88	Mycobacterium_phage	4.8e-62	37.1

DBSCAN-SWA_376

5399933 : 5401294

Orpheovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014383557.1\|5399933_5400944_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	7.0e-68	47.6
WP_008262471.1\|5400940_5401294_+	thioredoxin	A0A1J0GW78	Streptomyces_phage	1.5e-25	56.7

DBSCAN-SWA_377

5404687 : 5405503

Natrialba_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026071093.1\|5404687_5405503_-	ParA family protein	Q8JL10	Natrialba_phage	5.0e-24	33.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_016947

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection