CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017740	Helicobacter pylori Shi169, complete genome	1 crisprs	c2c9_V-U4,cas2,DEDDh	0	1	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_017740_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017740_1

1011049-1011124

Unclear

Consensus_repeat	Method
TCTTCAAACTCCTGGTGGTTTTCTT	CRISPRCasFinder

1 spacers

cas2

The CRISPR arrays of NC_017740_1

>merge|NC_017740|1|1011049-1011124|CRISPRCasFinder
TCTTCAAACTCCTGGTGGTTTTCTTCATCATCGTTTTCATCTTTTTTAATCTCTTCAAACTCCCGGTGGTTTTCTT

>NC_017740|1|1|1011049-1011124|CRISPRCasFinder
TCTTCAAACTCCTGGTGGTTTTCTT	CATCATCGTTTTCATCTTTTTTAATC
TCTTCAAACTCCCGGTGGTTTTCTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017740.1\|WP_000880304.1\|1016419_1016701_-\|DUF3240-domain-containing-protein	unknown	unknown	unknown
NC_017740.1\|WP_001150910.1\|1008583_1009480_-\|glycine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|236473
NC_017740.1\|WP_000670070.1\|1003656_1004289_-\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380324
NC_017740.1\|WP_000472183.1\|1005894_1007076_-\|3-deoxy-D-manno-octulosonic-acid-transferase	unknown	unknown	gnl\|CDD\|235589
NC_017740.1\|WP_000870496.1\|1019770_1020850_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273386
NC_017740.1\|WP_080025003.1\|1020846_1022082_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367035
NC_017740.1\|WP_001091752.1\|1007076_1007841_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224495
NC_017740.1\|WP_000271454.1\|1016064_1016352_-\|endoribonuclease-VapD	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|225846
NC_017740.1\|WP_001010890.1\|1027269_1028580_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|235656
NC_017740.1\|WP_000409607.1\|1005149_1005878_-\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NC_017740.1\|WP_000401705.1\|1009493_1010432_-\|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|234629
NC_017740.1\|WP_001229701.1\|1007850_1008582_-\|Nif3-like-dinuclear-metal-center-hexameric-protein	unknown	unknown	gnl\|CDD\|213534
NC_017740.1\|WP_001165224.1\|1026915_1027197_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	unknown	unknown	gnl\|CDD\|129241
NC_017740.1\|WP_080024979.1\|1016711_1019774_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|226220
NC_017740.1\|WP_000995098.1\|1004285_1005140_-\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|273128
NC_017740.1\|WP_000555173.1\|1022131_1024234_-\|glycine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|272962
NC_017740.1\|WP_000669158.1\|1002367_1003024_+\|nicotinamide-nucleotide-amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|129303
NC_017740.1\|WP_000476666.1\|1003025_1003592_-\|hypothetical-protein	unknown	unknown	unknown
NC_017740.1\|WP_000681993.1\|1024345_1025413_+\|hypothetical-protein	unknown	unknown	unknown
NC_017740.1\|WP_000057761.1\|1025425_1026901_+\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|130374

Protein	Function_ID	Function_description	E-value
NC_017740.1\|WP_001150910.1\|1008583_1009480_-\|glycine--tRNA-ligase-subunit-alpha	gnl\|CDD\|236473	PRK09348, glyQ, glycyl-tRNA synthetase subunit alpha; Validated.	0
NC_017740.1\|WP_000670070.1\|1003656_1004289_-\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|380324	cd02149, NfsB-like, nitroreductase similar to Escherichia coli NfsB. NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family includes FRase I in Vibrio fischeri, wihich reduces FMN into FMNH2 as part of the bioluminescent reaction. The family also includes oxygen-insensitive nitroreductases that use NADH or NADPH as an electron donor in the ping pong bi bi mechanism. This type of nitroreductase can be used in cancer chemotherapy to activate a range of prodrugs.	1.01724e-62
NC_017740.1\|WP_000472183.1\|1005894_1007076_-\|3-deoxy-D-manno-octulosonic-acid-transferase	gnl\|CDD\|235589	PRK05749, PRK05749, 3-deoxy-D-manno-octulosonic-acid transferase; Reviewed.	9.11153e-168
NC_017740.1\|WP_080025003.1\|1020846_1022082_-\|hypothetical-protein	gnl\|CDD\|367035	pfam02321, OEP, Outer membrane efflux protein. The OEP family (Outer membrane efflux protein) form trimeric channels that allow export of a variety of substrates in Gram negative bacteria. Each member of this family is composed of two repeats. The trimeric channel is composed of a 12 stranded all beta sheet barrel that spans the outer membrane, and a long all helical barrel that spans the periplasm.	8.40338e-13
NC_017740.1\|WP_001091752.1\|1007076_1007841_-\|hypothetical-protein	gnl\|CDD\|224495	COG1579, COG1579, Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only].	3.26859e-60
NC_017740.1\|WP_000271454.1\|1016064_1016352_-\|endoribonuclease-VapD	gnl\|CDD\|225846	COG3309, VapD, Uncharacterized virulence-associated protein D [Function unknown].	2.71134e-45
NC_017740.1\|WP_001010890.1\|1027269_1028580_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|235656	PRK05964, PRK05964, adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional.	0
NC_017740.1\|WP_000870496.1\|1019770_1020850_-\|hypothetical-protein	gnl\|CDD\|273386	TIGR00999, Nickel-cobalt-cadmium_resistance_protein_NccB, Membrane Fusion Protein cluster 2 (function with RND porters). [Transport and binding proteins, Other].	4.33123e-16
NC_017740.1\|WP_000401705.1\|1009493_1010432_-\|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	gnl\|CDD\|234629	PRK00094, gpsA, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.	1.23277e-124
NC_017740.1\|WP_001229701.1\|1007850_1008582_-\|Nif3-like-dinuclear-metal-center-hexameric-protein	gnl\|CDD\|213534	TIGR00486, Putative_GTP_cyclohydrolase_1_type_2, dinuclear metal center protein, YbgI/SA1388 family. The characterization of this family of uncharacterized proteins as orthologous is tentative. Members are found in all three domains of life. Several members (from Bacillus subtilis, Listeria monocytogenes, and Mycobacterium tuberculosis - all classified as Firmicutes within the Eubacteria) share a long insert relative to other members. [Unknown function, General].	2.2104e-78
NC_017740.1\|WP_001165224.1\|1026915_1027197_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	gnl\|CDD\|129241	TIGR00135, Glutamyl-tRNAGln_amidotransferase_subunit_C, aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit. Archaea, organelles, and many bacteria charge Gln-tRNA by first misacylating it with Glu and then amidating Glu to Gln. This small protein is part of the amidotransferase heterotrimer and appears to be important to the stability of the amidase subunit encode by gatA, but its function may not be required in every organism that expresses gatA and gatB. The seed alignment for this model does not include any eukaryotic sequence and is not guaranteed to find eukaryotic examples, although it does find some. Saccharomyces cerevisiae, which expresses the amidotransferase for mitochondrial protein translation, seems to lack a gatC ortholog. This model has been revised to remove the candidate sequence from Methanococcus jannaschii, now part of a related model. [Protein synthesis, tRNA aminoacylation].	7.05541e-26
NC_017740.1\|WP_080024979.1\|1016711_1019774_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|226220	COG3696, COG3696, Putative silver efflux pump [Inorganic ion transport and metabolism].	0
NC_017740.1\|WP_000995098.1\|1004285_1005140_-\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|273128	TIGR00544, Prolipoprotein_diacylglyceryl_transferase, prolipoprotein diacylglyceryl transferase. The conversion of lipoprotein precursors into lipoproteins consists of three steps. First, the enzyme described by this model transfers a diacylglyceryl moiety from phosphatidylglycerol to the side chain of a Cys that will become the new N-terminus. Second, the signal peptide is removed by signal peptidase II. Finally, the free amino group of the new N-terminal Cys is acylated by apolipoprotein N-acyltransferase. [Protein fate, Protein modification and repair].	1.84533e-104
NC_017740.1\|WP_000555173.1\|1022131_1024234_-\|glycine--tRNA-ligase-subunit-beta	gnl\|CDD\|272962	TIGR00211, Glycine--tRNA_ligase_beta_subunit, glycyl-tRNA synthetase, tetrameric type, beta subunit. The glycyl-tRNA synthetases differ even among the eubacteria in oligomeric structure. In Escherichia coli and most others, it is a heterodimer of two alpha chains and two beta chains, encoded by tandem genes. The genes are similar, but fused, in Chlamydia trachomatis. By contrast, the glycyl-tRNA synthetases of Thermus thermophilus and of archaea and eukaryotes differ considerably; they are homodimeric, mutually similar, and not detected by this model. [Protein synthesis, tRNA aminoacylation].	0
NC_017740.1\|WP_000669158.1\|1002367_1003024_+\|nicotinamide-nucleotide-amidohydrolase-family-protein	gnl\|CDD\|129303	TIGR00199, Putative_competence-damage_inducible_protein, amidohydrolase, PncC family. CinA is a DNA damage- or competence-inducible protein that is polycistronic with recA in a number of species. Several bacterial species have a protein consisting largely of the C-terminal domain of CinA but lacking the N-terminal domain, including nicotinamide mononucleotide (NMN) deamidase (3.5.1.42) proteins PncC in Shewanella oneidensis and ygaD in E. coli. [DNA metabolism, DNA replication, recombination, and repair].	1.0366e-73
NC_017740.1\|WP_000409607.1\|1005149_1005878_-\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	1.77631e-60
NC_017740.1\|WP_000057761.1\|1025425_1026901_+\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	gnl\|CDD\|130374	TIGR01307, pgm_bpd_ind, phosphoglycerate mutase (2,3-diphosphoglycerate-independent). This protein is about double in length of, and devoid of homology to the form of phosphoglycerate mutase that uses 2,3-bisphosphoglycerate as a cofactor. [Energy metabolism, Glycolysis/gluconeogenesis].	0

>NC_017740.1|WP_000401705.1|1009493_1010432_-|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase
MEIAVFGGGAWGRALAFAFGEKNEVKIISRRDLNEPLKKLNDALISKGSAPIEQVDLQRGLKAALYVIAISVQHLREWFQNASLPKNAKVLIASKGIEVLNRAFVSEIAKDFIDPNSLCFLAGPSFAAEIIQGLPCALVIHSNNQALALEFANKTPSFIRAYAQQDIIGGEIAGAYKNVIAIAGGVCDGLKLGNSAKASLLSRGLVEMQRFGAFFGGKTETFLGLSGAGDLFLTANSILSRNYRVGLGLAQNKPLEVVLEELGEVAEGVKTTNAIVEIARKYGIYTPIASELALLLKGKSVLESMNDLIRRA
>NC_017740.1|WP_001150910.1|1008583_1009480_-|glycine--tRNA-ligase-subunit-alpha
MQDFSSLLLKLQEYWKNQGCLVIQPYDIPAGAGTFHPATLLRSLDKKPWNVAYVAPSRRPTDGRYGENPNRLGSYYQFQVVIKPSPSNIQELYLKSLEVLGINLNEHDIRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQVGGIACNPIPVEITYGLERLAMYVQKVENILEIEWAKKDHGSVNYAQVHLESEYEFSKYHFEIASVKRLLEMFKNAQAEALHCLENKLPLPAYDFVMLCSHFFNILDARKAISVAERQNYILQIRDLAKGCAILYKEQEEEREERLKNALTKA
>NC_017740.1|WP_001229701.1|1007850_1008582_-|Nif3-like-dinuclear-metal-center-hexameric-protein
MALVKEVLEVLECLSPFELQESWDNSGLNVGSENHEFSEIIACLEITLKIALNAPKNALIITHHPLIFKPLKTLNDEAYPDNILKILIQKNISVISMHTNFDKTHLNKHFASVLLGFDGLMEKGLMLVKENANIEFDALVKKIKSSLGVGLLACVKSSPIIKDLAFVCGSGASMFSSLKAQSCLVTGDVKYHDAMIAQSLGISLIDATHYYSERGFALIVAEILHSFNYLVTIENFKNPLQII
>NC_017740.1|WP_001091752.1|1007076_1007841_-|hypothetical-protein
MNTHLKQLIEISHLDKEIDSLEPLIREKRKDLDKALNDKEAKNKAILNLEEEKLALKLQVSKNEQTLQDANAKIASIQKKMSEIKSERELRSLNIEEDIAKERSNQANREIENLQNEIKHKSEKQEDLKKEMLELEKLALELESLVESEVKNIKETQQIIFKKKEDLVEKTEPKIYSFYERIRRWAKNTSIVTIKKQACGGCFIRLNDKIYTEVLTSGDMITCPYCGRILYAEGAYENSAQPPKESQEESQELV
>NC_017740.1|WP_000472183.1|1005894_1007076_-|3-deoxy-D-manno-octulosonic-acid-transferase
MFKFFYLLFLTLGHLLGAPFIFFWSFKEKYRHSLKARFFLKDNFLKSEPVFWFHACSYGEVKSLEPIIQALKEPILISVTTNTGFELAAQTYQNLEHIEVRYLPFETLLFAWKKNLKRLKTLVVTEAELWFNVFDTAQKLGAKTMLINARISVRSYPKYQRFSFFYVLLFKRIDLVLVQSKDDKKRLLNLGAKKVVDFLNIKRFSKPVTASFYPKNPSALNIVLASTHEGEEKLGLKAFLEFKKTHQNARLFIVPRHPERFKSVQNLLQDALKTTRFSWECFSSKGFVECDILLVDRLGELNNFYQIADIVILGGSFVKMGGHNPLEPAFFNARLITGEYIFNQVALFELIKPYKIVQKEDLLDALLDYKNLGVARFLENGHDLNELLAFIKH
>NC_017740.1|WP_000409607.1|1005149_1005878_-|RluA-family-pseudouridine-synthase
MEKAYKILSVQENISHKKAKALIDLGLVSVGGKKLMVARKELPKNTHFSVQKVEKPSVIFEDENILALFKPPFIESYDLVSFFKGWVLLHRLDKETSGVILLVKENSEFHLKAKKAFKDRAVKKEYLALAQGIIEEEQEINAPILTIKTTKAFSKISKKGQEAVTIITPLKIINKKTLLKVGIKTGRTHQIRVHLKHINHPIIGDTLYNNEPGSAKRLMLHAHKISLLGYEFEAIPPKEFEF
>NC_017740.1|WP_000995098.1|1004285_1005140_-|prolipoprotein-diacylglyceryl-transferase
MNAWNTIYDQFNPIAFSLGSIEVHWYGLAYACAIVTAFYMALRMIQKDPKRFPIERKEFESYFLWAELGIVLGARVGYILIYEPNSSYYLTHFWQIFNPFDSNGDFVGIRGMSYHGGLVGFLIASYLYSRKDLKKLLIYLDLIAISLPLGYVFGRIGNFLNQELVGRIVPKDSHLGQIIGIMVGNELRYPSQLIEAFLEGVIVFLMVLWAKKHTKTHGLLIVVYGLGYSLMRFIAEFYREPDSQMGVYFLNLSMGQILSLLMVIVSLGILLYATKNSKKIKGNQ
>NC_017740.1|WP_000670070.1|1003656_1004289_-|NAD(P)H-dependent-oxidoreductase
MKFLDQEKRRQLLNERHSCKMFDSHYEFSSEELEEIAEIAMLSPSSYNTQPWHFVMVTNKDVKKQIAAHSYFNEEMIKSASALMVVCPLRPSELLPHSHYMQNLYPESYKVRVIPSFAQMLGVRFNHSMQKLESYILEQCYIAVGQICMGVSLMGLDSCIIGGFDPLKVGEILEERINKPKIACLIALGKRVAEASQKSRKSKVDTITWL
>NC_017740.1|WP_000476666.1|1003025_1003592_-|hypothetical-protein
MFKRMVLIALLGVFSSVSLSAKSILRDDGILVSDLKGMKSELSDAPAWVFEDPKVPYEEMGVAYIPINNKYLGIEQATLNAKLSLIVVFHEIMMRYKKRFMEQFHESDQTATNISYAIYNYLATKIQVANTYTNLKSEVAVVKIKLEGCQIEQIKRYLKASVENLNDNEIAYIAKVVQKELGSVCALR
>NC_017740.1|WP_000669158.1|1002367_1003024_+|nicotinamide-nucleotide-amidohydrolase-family-protein
MKFKFLNMDNESGFILIEKELERLNILAQVKEDCIELKGENIKQARIYLKTLFNSNIVELDDHQKSANALIERLKSLGLKIAVAESCSGGLLSHAFTSISGASAVFMGGVVCYNEEVKRELLKVNATTLKVFGVYSEECVKEMLLGVFLNFKVDLALAISGVAGPNGGSKANPVGTIYIGVQKLGSQALIDRCSFEGNRESIQNKSVEHALNMLARML
>NC_017740.1|WP_000271454.1|1016064_1016352_-|endoribonuclease-VapD
MYAVTFDLDTNCLNENAVNLSKVYSDIRKFMEQHGFKWQQGSVYFGDETINAVTCVATVQILAKQIPSFAICVKDVRMLKIEENNDLMPAIKIVL
>NC_017740.1|WP_000880304.1|1016419_1016701_-|DUF3240-domain-containing-protein
MLALEIYIDICLKDALIDYLFEKGFDDFFYVECYKYAASSLLLSQKEQVSGRKDYAKFKLFLSDEIALSLAKALKNQFASKEMKLFYSQTHGL
>NC_017740.1|WP_080024979.1|1016711_1019774_-|efflux-RND-transporter-permease-subunit
MMLASIIEFSLRQRIIVIVCAILVLFFGTYSFINTPVDAFPDISPTQVKIILKLPGSSPEEMENNIVRPLELELLGLKGQKSLRSISKYSISDITIDFDDSVDIYLARNIVNERLSSVMKDLPIGVEGGMAPIVTPLSDIFMFTIDGNITEIEKRQLLDFVIRPQLRMISGVADVNSIGGFSRAFVIVPDFNDMARLGISISDLEEAVRVNLRNSGAGRVDRDGETFLVKIQTASLSLEDIGKITVSTNLGHLHIKDFAKVISQSRTRLGFVTKDGVGETTEGLVLSLKDANTKEIIAQVYQKLEELKPFLPSGVSINVFYDRSEFTQKAIATVSKTLIEAVVLIVITLFLFLGNLRASVAVGVILPLSLSVAFIFIKLSDLTLNLMSLGGLIIAIGMLIDSAVVVVENAFEKLSSNTKTTKLHAIYRSCKEIAVSVVSGVVIIIVFFVPILTLHGLEGKMFRPLAQSIVYALLGTLVLSITIIPVVSSLVLKATPHSETFLTRFLNRIYAPLLEFFVHNPKKVILGAFVFLTASLSLFPFVGKNFMPALDEGDVVLSVETTPSISLDQSRDLMLNIESAIKKHVKEVKSIVARTGSDELGLDLGGLNQTDTFISFIPKKEWSVKTKDELLEKIMDSLKDFKGINFSFTQPIEMRISEMLTGVRGDLAVKIFGDDISELNKLSFQIAQVLKGIKGSSEVLTTLNEGVNYLCVTPNKEAMANVGITSDEFSKFLKSALEGLVVDVIPTGISRTPVMIRQESDFASSITKIKSLALTSKYGVLVPITSIAKIEEVDGPVSVVRENSMRMSVVRSNVVGRDLNSFVEEAKKVIAQNIKLPLSYYITYGGQFENQQRANKRLSTVIPLSILAIFFILFFTFKSIPLALLILLNIPFAVTGGLIALFAVGEYISVPASVGFIALFGIAVLNGVVMIGYFKELLLQGKSVEECVLLGAKRRLRPVLMTACIAGLGLIPLLFSHSVGSEVQKPLAIVVLGGLVTSSALTLLLLPPMFMLIAKKIKIN
>NC_017740.1|WP_000870496.1|1019770_1020850_-|hypothetical-protein
MKWALLWLMLMGVFSMGVSLEAKEYPEIVLEEKNLQPMGLKVIKLDKEIFSKGLPFNAYIDFDSKSSVVQSLSFDASVVAVYKREGEQVKAGDAICEVSSIDLSNLYFELQNNQNKLKIAKDITKKDLELYKAGVIPKREYQTSFLASQEMGLKVEQLESAFKSFGVDPKNPKGQYGFRIVARDSGLLALAPKNVGEKILAFTSYVRVSKSDNLIAQIKLPIGVSKSIKRDSPVYNEEGEKIGKIQSVSVVLDKGSNTILATALLDEGNYHVGEMVEMYIQGSQPKGSVLIPSNALIRNGKDYLVFVRTPKGFRPVVVQVLEERSKIFIVNAKNLHPNDSVAVGSLIGLKGMINNLGEE
>NC_017740.1|WP_080025003.1|1020846_1022082_-|hypothetical-protein
MSGVGTLDAKTFTLQEFFKEVETNSMELIGKKADFKSRLNEQRSVNAWDFPYIMNETSMVKNFQGIIEAQPRTLLMVRPKLPWVSSLLSKSLSIKTIQYDKSYQLSKNLAFIGAKRLYLTYVMTKEKYQVYVQREANFYSQLKIAKEKVKAGSMSEKDYINFKNSYLESKLAKTNVETKLIDLEKMLDTMLAIVEPVKEGAHFDTYLDHLHDVKVIGLDFEYVRLEPEALKFKLDRSLYVDILDLTAKDYQVNAKLANRDVFNGFEFGIGSESYNSSTNLSVEVYIPLPVTPKNIYQKRKFLDLQSGTLAQNEVMKRNIRINANSYLNQLKTKEAYIETQKEAIANKKRLMEMGRIAYEAQKIGLFEYLIYQNSYMDALITLAEAKIEYIDISALLEETLGESLTRLGVLH
>NC_017740.1|WP_000555173.1|1022131_1024234_-|glycine--tRNA-ligase-subunit-beta
MHSDELLVEILVEELPAQALLNEYKEMPKKLHALFNKCTLEVGKIEIFYTPRRLCLLVKDFPLLTQETKEEFFGPPVKIACNHQDKTQGLNELGLGFYQKLGLKDHQHFQTAFKNNNEVLYHAKIHAKEPTKDLIMPIVLEFLEGLNFGKSMRWGNVEKSFIRPIHNICVLFNGENFNDIEVKEYGFKTKQATKAHRQEGFDFIQVDSPKAYFEVLEKNHVILDPKKREAKILQEIKELETKHRIIVEIDRDLLDEVVAITEYPSALLGEFDKAFLKLPNEIIITSMKENQRYFAAFNQKSQESPILHNGFIVVSNAISKDKQKIIAGNQKVLKARLSDAVFFYENDLKKPLDNAPLESVVFVQGLGTLKDKMEREAIIAQYLTQKYASSLNMPLEKALELVGRAVRIAKADLLSEVVYEFSELQGIMGYYYALKQNENELVALSVKEQYLPASENAPLPSSVFSAIVALSLKLDSLFSLFSVGKIPSGSKDPFALRRSSFGLLKIVVHYELEFDLKADLKNLFEKVGVYQSFDLEVLEKFLLERFNNLIDCNPSIIRSVLNTNERGIVKIIQKVKALKRFLDDPKNAQKKELLFSAFKRLANINKDRNPNESSEFSISLFKESQEHALFEAFNAIKTSAFESLDSKIEAYFGLHAPLEEYFKSVLVMDKDIEIQKNRKNFLWGVYQSFLEIGDIKEIAI
>NC_017740.1|WP_000681993.1|1024345_1025413_+|hypothetical-protein
MKHLTPLTHTIFKALLLGTALSASLSLAAAESPAKTEPKSAKGVKNKPKSPVTKVMMTNCDSIKDFNAKQKEVLKAAYQFGSKENLGYEMASIAWKESCAGVYKINFSDPSAGVYHSYIPSVLKSYGHNDSPFLRNVMGELLIKDDAFASEVALKELLYWKTRYHDNLKDMIKSYNKGSRWERSEKSNAEAEKYYEEIQDRIRRLKESKIFDSQSSNDQELQKSANSNLDLDPIGNAMPQTLAKTEAKETQTEETQAEKSQEMKEATSEQTTSKPEKAKDKPMHLAQINSADFTPAKKSPQKPAKMSQKRSPKNNKNNIKSSTKTASKKQEVCKNCSPGQRNAILANRITLMQEL
>NC_017740.1|WP_000057761.1|1025425_1026901_+|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase
MAQKTLLIITDGIGYRKDSDYNAFFHAKKPTYDLMFKTLPYSLIDTHGLSVGLPKGQMGNSEVGHMCIGAGRVLYQDLVKISLSLQNDGLKNNPAFLNTIHKSKVVHLMGLMSDGGVHSHIEHFIALALECEKSHKKVCLHLITDGRDVAPKSALTYLKQMQNICNENIQIATISGRFYAMDRDKRFERIKLAYHSLMGLNHTPLSPSEYIQSQYDKNTTDEFIMPACFKDYCGMQDGESFIFINFRNDRAREIVSALGQKEFNGFKRETFKKLHIATMTPYDNTFPYPVLFPKESVQNTLAEVVSQHNLTQSHIAETEKYAHVTFFINGGVEAPFKNENRVLIQSPKVTTYDLKPEMSAKEVTLAVLDQMELGTDLIIVNFANGDMVGHTGNFEASIKAVEEVDACLGEILSLAKKLDYAMLLTSDHGNCERMKDENQNPLTNHTAGSVYCFVLGNGVRSIKNGALNNIASSVLKLMGLKAPATMDEPLF
>NC_017740.1|WP_001165224.1|1026915_1027197_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC
MQIDDALLQRLEKLSMLEIKDEHKESVKGHLVEVLGFVENIFALETSALKTDTKLCTPLREDEPKSQPHIAKEILSQNKHSQDHYFVVPKIIE
>NC_017740.1|WP_001010890.1|1027269_1028580_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MNFQENLAALDLEYLWHPCSQMQEHQNFPIIPIKKAQGIYLYDFNGNAYMDLISSWWVNLFGHNNAYISQQLKNQIDNLEHVLLASFSHKPIITLSQRLCQLTHMDKCFYADNGSSCIEIALKMSYHAHFLKNQTSRKKLFLSLSNSYHGETLGALSAGDVKLYKDTYTPLLLKNLTTPVPKNDNEIESSLNALKRLLDKNHEEICAFIAEPLLQCAGNMHIYSTKYLKQAVLLCKQKNIHIIFDEIATGFGRTGSMFAFEQCEIEPDFLCLSKGISGGYLPLSALLTRNEIYNQFYAPYEENKAFLHSHSYTGNALACACANATLDIFEKENVIEKNKALSEFIFNALQNALKPLIEQQVVSDLRHLGMVFAFEVFIQTNERLSLAVFKKALTKGLLLRPLNNTIYLMPPYIITHEEINKAIVGLVEILDGLKKG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	KY290955	Aeromonas phage 65.2, complete genome	16195-16220	3	0.885
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	NC_015251	Aeromonas phage 65, complete genome	16198-16223	3	0.885
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	NZ_LR214939	Mycoplasma salivarium strain NCTC10113 plasmid 2	144988-145013	4	0.846
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	737183-737208	4	0.846
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	KU878088	Bacillus phage AR9, complete genome	90316-90341	4	0.846
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	MF360957	Bacillus virus PBS1, complete genome	619-644	4	0.846
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	CP017837	Proteobacteria phage MWH-Nonnen-W8red 2 genome	19811-19836	4	0.846
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	NZ_CP011159	Moraxella ovis strain 199/55 plasmid pMOV1, complete sequence	9561-9586	5	0.808
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	NZ_CP011350	Bacillus thuringiensis strain YC-10 plasmid pYC1, complete sequence	493220-493245	5	0.808
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	NZ_CP013056	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-1, complete sequence	132281-132306	5	0.808
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	NZ_AP014866	Bacillus thuringiensis serovar tolworthi strain Pasteur Institute Standard strain plasmid pKK2, complete sequence	109749-109774	5	0.808
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	MN856056	Myoviridae sp. isolate 80, complete genome	13220-13245	5	0.808
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	MH319754	Marine virus AG-345-L05 Ga0172272_11 genomic sequence	141890-141915	5	0.808
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	NZ_CP004876	Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMB299, complete sequence	32121-32146	5	0.808
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	NC_017203	Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT281, complete sequence	67689-67714	5	0.808
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	NC_020384	Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-285, complete sequence	71912-71937	5	0.808
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	NZ_CP015152	Bacillus thuringiensis strain Bc601 plasmid pBTBC2, complete sequence	70307-70332	5	0.808
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	NZ_CP004861	Bacillus thuringiensis serovar kurstaki str. YBT-1520 plasmid pBMB293, complete sequence	32991-33016	5	0.808
NC_017740_1	1.1\|1011074\|26\|NC_017740\|CRISPRCasFinder	1011074-1011099	26	NZ_CP010091	Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB267, complete sequence	27264-27289	5	0.808

1. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to KY290955 (Aeromonas phage 65.2, complete genome) position: , mismatch: 3, identity: 0.885

catcatcgttttcatcttttttaatc	CRISPR spacer
catcatcgttatcatcttttgtaatg	Protospacer
********** ********* ****

2. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to NC_015251 (Aeromonas phage 65, complete genome) position: , mismatch: 3, identity: 0.885

catcatcgttttcatcttttttaatc	CRISPR spacer
catcatcgttatcatcttttgtaatg	Protospacer
********** ********* ****

3. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to NZ_LR214939 (Mycoplasma salivarium strain NCTC10113 plasmid 2) position: , mismatch: 4, identity: 0.846

catcatcgttttcatcttttttaatc	CRISPR spacer
catcatcattttcatattttttaaat	Protospacer
*******.******* ******** .

4. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 4, identity: 0.846

catcatcgttttcatcttttttaatc	CRISPR spacer
aatcatcgttttcatctatattaatt	Protospacer
 **************** * *****.

5. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to KU878088 (Bacillus phage AR9, complete genome) position: , mismatch: 4, identity: 0.846

catcatcgttttcatcttttttaatc	CRISPR spacer
catcatcgtcttcatcttctttaagg	Protospacer
*********.********.*****

6. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to MF360957 (Bacillus virus PBS1, complete genome) position: , mismatch: 4, identity: 0.846

catcatcgttttcatcttttttaatc	CRISPR spacer
catcatcgtcttcatcttctttaagg	Protospacer
*********.********.*****

7. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to CP017837 (Proteobacteria phage MWH-Nonnen-W8red 2 genome) position: , mismatch: 4, identity: 0.846

catcatcgttttcatcttttttaatc	CRISPR spacer
catcatctttttcttcttttttattg	Protospacer
******* ***** ********* *

8. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to NZ_CP011159 (Moraxella ovis strain 199/55 plasmid pMOV1, complete sequence) position: , mismatch: 5, identity: 0.808

catcatcgttttcatcttttttaatc	CRISPR spacer
gctcaccgttttcatctttttcaatt	Protospacer
  ***.***************.***.

9. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to NZ_CP011350 (Bacillus thuringiensis strain YC-10 plasmid pYC1, complete sequence) position: , mismatch: 5, identity: 0.808

catcatcgttttcatcttttttaatc	CRISPR spacer
aatcttcgatttcatcttttttaact	Protospacer
 *** *** ***************..

10. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to NZ_CP013056 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-1, complete sequence) position: , mismatch: 5, identity: 0.808

catcatcgttttcatcttttttaatc	CRISPR spacer
aatcttcgatttcatcttttttaact	Protospacer
 *** *** ***************..

11. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to NZ_AP014866 (Bacillus thuringiensis serovar tolworthi strain Pasteur Institute Standard strain plasmid pKK2, complete sequence) position: , mismatch: 5, identity: 0.808

catcatcgttttcatcttttttaatc	CRISPR spacer
aatcttcgatttcatcttttttaact	Protospacer
 *** *** ***************..

12. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to MN856056 (Myoviridae sp. isolate 80, complete genome) position: , mismatch: 5, identity: 0.808

catcatcgttttcatcttttttaatc	CRISPR spacer
tttcatctttttcatcttttttatcc	Protospacer
. ***** *************** .*

13. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to MH319754 (Marine virus AG-345-L05 Ga0172272_11 genomic sequence) position: , mismatch: 5, identity: 0.808

catcatcgttttcatcttttttaatc	CRISPR spacer
tatcatctttttcatcctttttaagt	Protospacer
.****** ********.******* .

14. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to NZ_CP004876 (Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMB299, complete sequence) position: , mismatch: 5, identity: 0.808

catcatcgttttcatcttttttaatc	CRISPR spacer
aatcttcgatttcatcttttttaact	Protospacer
 *** *** ***************..

15. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to NC_017203 (Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT281, complete sequence) position: , mismatch: 5, identity: 0.808

catcatcgttttcatcttttttaatc	CRISPR spacer
aatcttcgatttcatcttttttaact	Protospacer
 *** *** ***************..

16. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to NC_020384 (Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-285, complete sequence) position: , mismatch: 5, identity: 0.808

catcatcgttttcatcttttttaatc	CRISPR spacer
aatcttcgatttcatcttttttaact	Protospacer
 *** *** ***************..

17. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to NZ_CP015152 (Bacillus thuringiensis strain Bc601 plasmid pBTBC2, complete sequence) position: , mismatch: 5, identity: 0.808

catcatcgttttcatcttttttaatc	CRISPR spacer
aatcttcgatttcatcttttttaact	Protospacer
 *** *** ***************..

18. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to NZ_CP004861 (Bacillus thuringiensis serovar kurstaki str. YBT-1520 plasmid pBMB293, complete sequence) position: , mismatch: 5, identity: 0.808

catcatcgttttcatcttttttaatc	CRISPR spacer
aatcttcgatttcatcttttttaact	Protospacer
 *** *** ***************..

19. spacer 1.1|1011074|26|NC_017740|CRISPRCasFinder matches to NZ_CP010091 (Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB267, complete sequence) position: , mismatch: 5, identity: 0.808

catcatcgttttcatcttttttaatc	CRISPR spacer
aatcttcgatttcatcttttttaact	Protospacer
 *** *** ***************..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

292259 : 301627

Enterobacteria_phage(33.33%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000382880.1\|292259_293522_+	exodeoxyribonuclease VII large subunit	A0A1V0SD82	Indivirus	3.8e-39	38.2
WP_012443295.1\|293540_294713_-	site-specific DNA-methyltransferase	Q1MVP0	Enterobacteria_phage	1.2e-23	27.1
WP_001160145.1\|294705_295320_-	hypothetical protein	NA	NA	NA	NA
WP_001274344.1\|295378_296638_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5RFS3	Helicobacter_phage	1.7e-236	98.6
WP_001042542.1\|296612_297266_-\|transposase	IS607 family transposase	A0A1S5RFV4	Helicobacter_phage	3.8e-115	98.6
WP_080024966.1\|297515_298229_+	endonuclease	NA	NA	NA	NA
WP_000806088.1\|298225_298984_+	site-specific DNA-methyltransferase	A0A0N9PB81	Sulfolobus_monocaudavirus	7.6e-67	52.7
WP_001048000.1\|299056_301627_+	AAA domain-containing protein	H6X3M6	Enterobacteria_phage	4.3e-114	34.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage