CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017741	Helicobacter pylori Shi112, complete genome	5 crisprs	cas14j,c2c9_V-U4,cas3,cas2,DEDDh	2	3	2	0

1. NC_017741

CRISPR-Cas detection and classification

Crispr_ID: NC_017741_2

• CRISPR_ID: NC_017741_2
• CRISPR_location: 55518-55603
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017741_2

Consensus_repeat	Method
AGATAAAGACAATCTAACTAAAG	CRISPRCasFinder

spacers of NC_017741_2

>2.1|55541|40|NC_017741|CRISPRCasFinder
AGAAAGCAGAACTCACTGAAAAGAATCAAAAGCTGACTAC

CRISPR arrays and Neighbor proteins around NC_017741_2

CRISPR arrays

The CRISPR arrays of NC_017741_2

>merge|NC_017741|2|55518-55603|CRISPRCasFinder
AGATAAAGACAATCTAACTAAAGAGAAAGCAGAACTCACTGAAAAGAATCAAAAGCTGACTACAGAAAAAGACAATCTAACTAAAG

>NC_017741|2|2|55518-55603|CRISPRCasFinder
AGATAAAGACAATCTAACTAAAG	AGAAAGCAGAACTCACTGAAAAGAATCAAAAGCTGACTAC
AGAAAAAGACAATCTAACTAAAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017741.1|WP_000848994.1|53628_53838_+|hypothetical-protein	unknown	unknown	unknown
NC_017741.1|WP_000491338.1|61516_61867_+|hypothetical-protein	unknown	unknown	unknown
NC_017741.1|WP_000614655.1|46602_47301_-|site-specific-DNA-methyltransferase	unknown	unknown	gnl|CDD|334588
NC_017741.1|WP_001199225.1|43309_45619_-|carbamoyltransferase-HypF	unknown	unknown	gnl|CDD|272929
NC_017741.1|WP_000238747.1|65156_65756_-|urease-accessory-protein-UreG	unknown	unknown	gnl|CDD|129208
NC_017741.1|WP_000827214.1|45558_46551_-|AguA-family-protein	unknown	unknown	gnl|CDD|225505
NC_017741.1|WP_001169360.1|49743_53301_-|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143443
NC_017741.1|WP_000049126.1|59055_59316_+|hypothetical-protein	unknown	unknown	gnl|CDD|377587
NC_017741.1|WP_000583051.1|66556_67069_-|urease-accessory-protein-UreE	unknown	unknown	gnl|CDD|237322
NC_017741.1|WP_000901278.1|67070_67658_-|acid-activated-urea-channel	unknown	unknown	gnl|CDD|259831
NC_017741.1|WP_000659844.1|39960_41106_+|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl|CDD|273644
NC_017741.1|WP_080024735.1|65784_66501_-|urease-accessory-protein-UreF	unknown	unknown	gnl|CDD|223900
NC_017741.1|WP_000724275.1|67850_69560_-|urease-subunit-beta	unknown	unknown	gnl|CDD|184438
NC_017741.1|WP_000992785.1|54377_55205_+|hypothetical-protein	unknown	unknown	gnl|CDD|275056
NC_017741.1|WP_000510289.1|48217_49717_-|sodium/proline-symporter-PutP	unknown	unknown	gnl|CDD|273981
NC_017741.1|WP_000447915.1|61089_61515_+|SMI1/KNR4-family-protein	unknown	unknown	gnl|CDD|378155
NC_017741.1|WP_000378782.1|42308_43307_-|hydrogenase-expression/formation-protein-HypE	unknown	unknown	gnl|CDD|273984
NC_017741.1|WP_001002520.1|41098_42031_+|GDP-L-fucose-synthase	unknown	unknown	gnl|CDD|187550
NC_017741.1|WP_000628956.1|58476_59040_+|hypothetical-protein	unknown	unknown	unknown
NC_017741.1|WP_001099459.1|64359_65157_-|urease-accessory-protein-UreD	unknown	unknown	gnl|CDD|223899

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017741.1|WP_000901278.1|67070_67658_-|acid-activated-urea-channel	gnl|CDD|259831	cd13404, UreI_AmiS_like, UreI/AmiS family, proton-gated urea channel and putative amide transporters. This family includes UreI proton-gated urea channels as well as putative amide transporters (AmiS of the amidase gene cluster). Helicobacter pylori UreI (HpUreI), a proton-gated inner membrane urea channel opens in acidic pH to allow urea influx to the cytoplasm. There urea is metabolized, producing NH3 and CO2, leading to buffering of the periplasm. This action is essential for the survival of H. pylori in the stomach, and has been identified as a mechanism that could be clinically targeted to prevent various illnesses associated with infection by H. pylori. UreI and the related amide channels (AmiS) appear to function as hexamers, and have 6 predicted transmembrane segments. UreI has also been shown have a lipid "plug" in the center of the hexamer. Urea enters at the periplasmic opening of UreI and must pass 2 constriction sites, one on each side of a conserved Glu (Glu 177, H. pylori numbering), to reach the cytoplasm. Urea/thiourea selectivity is diminished by mutation of a conserved Trp to Ala or Phe in constriction site 2 (cytoplasmic). Channel functionality is greatly diminished by mutation of a conserved Trp in constriction site 1 (periplasmic) and a conserved Tyr in constriction site 2, and to a lesser extent a conserved Phe in site 1. In the cytoplasm, urease hydrolyzes urea to form ammonia and carbamate, which decomposes to carbonic acid. UreI is fully open at pH 5.0 to facilitate urea influx, but closes at neutral pH, preventing over-alkalization. Glu 177 (H. pylori numbering) is present in urea channel proteins, but absent in the related amide channels, suggesting that it plays a role in urea specificity.	2.3886e-74
NC_017741.1|WP_000614655.1|46602_47301_-|site-specific-DNA-methyltransferase	gnl|CDD|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	3.28481e-58
NC_017741.1|WP_001199225.1|43309_45619_-|carbamoyltransferase-HypF	gnl|CDD|272929	TIGR00143, Carbamoyltransferase_HypF, [NiFe] hydrogenase maturation protein HypF. A previously described regulatory effect of HypF mutatation is attributable to loss of activity of a regulatory hydrogenase. A zinc finger-like region CXXCX(18)CXXCX(24)CXXCX(18)CXXC region further supported the regulatory hypothesis. However, more recent work (PUBMED:11375153) shows the direct effect is on the activity of expressed hydrogenases with nickel/iron centers, rather than on expression. [Protein fate, Protein modification and repair].	0
NC_017741.1|WP_000238747.1|65156_65756_-|urease-accessory-protein-UreG	gnl|CDD|129208	TIGR00101, Urease_accessory_protein_UreG, urease accessory protein UreG. This model represents UreG, a GTP hydrolase that acts in the assembly of the nickel metallocenter of urease. It is found only in urease-positive species, although some urease-positive species (e.g. Bacillus subtilis) lack this protein. A similar protein, hypB, is an accessory protein for expression of hydrogenase, which also uses nickel. [Central intermediary metabolism, Nitrogen metabolism].	2.71579e-140
NC_017741.1|WP_000827214.1|45558_46551_-|AguA-family-protein	gnl|CDD|225505	COG2957, COG2957, Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism].	0
NC_017741.1|WP_001169360.1|49743_53301_-|aldehyde-dehydrogenase-family-protein	gnl|CDD|143443	cd07125, ALDH_PutA-P5CDH, Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA. The proline catabolic enzymes of the aldehyde dehydrogenase (ALDH) protein superfamily, proline dehydrogenase and Delta(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH, (EC=1.5.1.12 )), catalyze the two-step oxidation of proline to glutamate; P5CDH catalyzes the oxidation of glutamate semialdehyde, utilizing NAD+ as the electron acceptor. In some bacteria, the two enzymes are fused into the bifunctional flavoenzyme, proline utilization A (PutA) These enzymes play important roles in cellular redox control, superoxide generation, and apoptosis. In certain prokaryotes such as Escherichia coli, PutA is also a transcriptional repressor of the proline utilization genes.	0
NC_017741.1|WP_000049126.1|59055_59316_+|hypothetical-protein	gnl|CDD|377587	pfam06013, WXG100, Proteins of 100 residues with WXG. ESAT-6 is a small protein appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. homologs have been detected in other Gram-positive bacterial species. It may represent a novel secretion system potentially driven by the pfam01580 domains in the YukA-like proteins.	0.00136638
NC_017741.1|WP_000583051.1|66556_67069_-|urease-accessory-protein-UreE	gnl|CDD|237322	PRK13261, ureE, urease accessory protein UreE; Provisional.	1.65726e-45
NC_017741.1|WP_000659844.1|39960_41106_+|GDP-mannose-4,6-dehydratase	gnl|CDD|273644	TIGR01472, GDP-mannose_46_dehydratase_1, GDP-mannose 4,6-dehydratase. Alternate name: GDP-D-mannose dehydratase. This enzyme converts GDP-mannose to GDP-4-dehydro-6-deoxy-D-mannose, the first of three steps for the conversion of GDP-mannose to GDP-fucose in animals, plants, and bacteria. In bacteria, GDP-L-fucose acts as a precursor of surface antigens such as the extracellular polysaccharide colanic acid of E. coli. Excluded from this model are members of the clade that score poorly because of highly dervied (phylogenetically long-branch) sequences, e.g. Aneurinibacillus thermoaerophilus Gmd, described as a bifunctional GDP-mannose 4,6-dehydratase/GDP-6-deoxy-D-lyxo-4-hexulose reductase (PUBMED:11096116). [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NC_017741.1|WP_080024735.1|65784_66501_-|urease-accessory-protein-UreF	gnl|CDD|223900	COG0830, UreF, Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones].	8.54453e-94
NC_017741.1|WP_000724275.1|67850_69560_-|urease-subunit-beta	gnl|CDD|184438	PRK13985, ureB, urease subunit alpha.	0
NC_017741.1|WP_000992785.1|54377_55205_+|hypothetical-protein	gnl|CDD|275056	TIGR04211, hypothetical_protein, SH3 domain protein. Members of this protein family have a signal peptide, a strongly conserved SH3 domain, a variable region, and then a C-terminal hydrophobic transmembrane alpha helix region.	1.69842e-08
NC_017741.1|WP_000510289.1|48217_49717_-|sodium/proline-symporter-PutP	gnl|CDD|273981	TIGR02121, Osmoregulated_proline_transporter, sodium/proline symporter. This family consists of the sodium/proline symporter (proline permease) from a number of Gram-negative and Gram-positive bacteria and from the archaeal genus Methanosarcina. Using the related pantothenate permease as an outgroup, candidate sequences from Bifidobacterium longum and several from archaea are found to be outside the clade defined by known proline permeases. These sequences, scoring between 570 and -40, define the range between trusted and noise cutoff scores. [Transport and binding proteins, Amino acids, peptides and amines].	0
NC_017741.1|WP_000447915.1|61089_61515_+|SMI1/KNR4-family-protein	gnl|CDD|378155	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1). Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.	6.57565e-07
NC_017741.1|WP_000378782.1|42308_43307_-|hydrogenase-expression/formation-protein-HypE	gnl|CDD|273984	TIGR02124, Hydrogenase_expression/formation_protein_HypE, hydrogenase expression/formation protein HypE. This family contains HypE (or HupE), a protein required for expression of catalytically active hydrogenase in many systems. It appears to be an accessory protein involved in maturation rather than a regulatory protein involved in expression. HypE shows considerable homology to the thiamine-monophosphate kinase ThiL (TIGR01379) and other enzymes.	5.19443e-172
NC_017741.1|WP_001002520.1|41098_42031_+|GDP-L-fucose-synthase	gnl|CDD|187550	cd05239, GDP_FS_SDR_e, GDP-fucose synthetase, extended (e) SDRs. GDP-fucose synthetase (aka 3, 5-epimerase-4-reductase) acts in the NADP-dependent synthesis of GDP-fucose from GDP-mannose. Two activities have been proposed for the same active site: epimerization and reduction. Proteins in this subgroup are extended SDRs, which have a characteristic active site tetrad and an NADP-binding motif, [AT]GXXGXXG, that is a close match to the archetypical form. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.99375e-140
NC_017741.1|WP_001099459.1|64359_65157_-|urease-accessory-protein-UreD	gnl|CDD|223899	COG0829, UreH, Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones].	2.38528e-106

Protein sequences

>NC_017741.1|WP_000992785.1|54377_55205_+|hypothetical-protein
MNALKNSQQVLENEKAELKTEKDNLTKANAELKTEKERLTKEKTELTEKNKELDDQVGLLKGQIKSLEQSQQVLKNENTDLDNKITDLSKENQNLTKEKTELTEKNQKLTTEKDNLTTDLSNAKIQAIQANQEKDKLEQKHAPYKKLEKLYEVFLEVKGCLNFNFVEKTHSAMDLIASVLSDSKYYLESLYNKASQELSDRKSDKGEKLAELFDLLFEYVKDNKFERLKEPSAYDPTCKKLYPEQNTSGKMQRVVLIGYTYDKKTTHYTIVDMGS
>NC_017741.1|WP_000848994.1|53628_53838_+|hypothetical-protein
MKTIKNGIMIGTLGALLLSGCSSFDAQRFACLPKDHSLKDASTKKEVQYTPKGFFDPYSSNLNHWDSTF
>NC_017741.1|WP_001169360.1|49743_53301_-|aldehyde-dehydrogenase-family-protein
MQKIIDDSLELAKKLQDSISNHLSEQEKAFHSKMQKLLNNPENKVMLIELMDRSFRCLDNKARFEMIEHVLDKYKSREIFSSFEKLLLMGFLSFGKMLPDMSVPFFVNKIRSDTKAMVLDQEESQLKERILKRKNEKIILNVNFIGEEVLGEEEASARFEKYSQALKSNYIQYISIKITTIFSQINILDFEYSKKEIVKRLDALYALALEEEKKQGMPKFINLDMEEFRDLELTVESFMESIAKFDLNAGIVLQAYIPDSYEYLKKLHAFSKERVLKGLKPIKIRFVKGANMESEETIASVKDWALPTFSNKQDTDSNYNKMLDFVLEGDNYKYIHIGAASHNIFEIAYVYTRIHALNDPVVLEHFSFEMLEGMSLQASQELKEMHKLILYAPVCDEAHFNNAIAYLVRRLDENTSSDNFMKAFFNLKVGTSEWEDQEQRFLNSLKGIATLDNATHRTQDRNAKQSGHTTYPNHSFKNESDTDFILKANREWAKKVREKMHNAPILELYPEMDGRFEDPNLTPLEVFDKIHHKKIASVHLADREAILKALEVAKSDKNRFSQKSFTEIHALMSQTAQIFRERRGDLIGISALEVGKTFAETDAEVSEAIDFLEFYPYSLRVLQEQNKKTKFTPKGVGVVIAPWNFPVGISVGTIAAPLAAGNRVIYKPSSLSSVTGYKLCECFWDAGVPRDALIYLPSKGSDISEHLLKDESIKFAILTGGEDTAYKMLEANPTLALSAETGGKNATIVSKMADRDQAIKNVIHSAFSNSGQKCSATSLLVLEKEVYEDENFKKTLIDATLSLSVGDPFDFKNKIGTLADKPNEKVIKAIDELKSYENYEIPVSFVNDNPYLMKPSIKYGTKKGDFTHQTELFTPILSVMKAQDLDEAIDIVNSTGYGLTSALESLDEREWEYYLKRIEAGNIYINKPTTGAIVLRQPFGGVKKSAVGFGRKVGIFNYITQFVNIHQEEEDENALKNPLSEALEGLTQKGYDEHTHELRRAIFMAKSYAYHYKHEFSQAKDYVKIRGEDNLFSYTKVKSVGYRITEKDTLSDMLGVALACLISQIPLTLSIENERANKDLSFFLECLKALRANAPIVYESLQKFSEKLNAFNRVRYLKSDLDLLHEQASALGIVLATAKPCLNGRFELLYYHLERSVSISYHRYGNLGSRVLRQPTCHKSCCAEK
>NC_017741.1|WP_000510289.1|48217_49717_-|sodium/proline-symporter-PutP
MGHVVLSTPIVTMFVAYSLLMLYIGFYFYRQNETTADYFLGDRSMGPIISALSAGASDMSGWLLMGLPGALYVGGLINSHIAIGLSLGALINWVFVAKRLRIYTSVIANSITISDYFETRFSDDKHILRLISAFVILIFFIFYISSGLVSGAKLFEATFGIQYTYALSIGTLIIVSYTFLGGYKAVCWTDLIQGLLMMSALIVVPIVMIIHLGGIGEGIKIIREIKPENLSFLQGSSMVAIISSLAWGLGYFGQPHILVRFMSIRSIKDVPKATTIGISWMVISLIGACVMGLLGVAYAHKFDLSLEDPEKIFIVMSQLLFNPWITGILLSAILAAVMSTASSQLLVSSSTIAEDFYATIFNKDAPQKLVMVISRLSVLGVACIAFFISTDRNASILSIVSYAWAGFGASFGSVILFSLFWSRMTRIGAIAGMLSGASTVILYDKFGKSFLDIYEIVPGFIVASIAIVVFSLFSSVRAGTKEAFETMLKEIKEIESLKY
>NC_017741.1|WP_000614655.1|46602_47301_-|site-specific-DNA-methyltransferase
MIQIHHANAFEIIKDFYQQNLKVDAIITDPPYNISVKNNFSTLKSAKRQGIDFGEWDKNFRLLEWIKRYAPLVNPNGCMVIFCSYRFISYIVDFLEENGFVVKDFIQWVKNNPMPRNINRRYVQDTEFALWAVKKKAKWVFNKPKNEKYLRPLILKSPVVGGLERVKHPTQKSLALMEKIISIHTNPNDIVLDPFMGSGTTGLACKHLKRNFIGIESEREYFQIAKKRLNLF
>NC_017741.1|WP_000827214.1|45558_46551_-|AguA-family-protein
MKRMLAEFEKIQAILMAFPHEFGDWAYCIKEARESFLNIIQTIAKHAKVLVCVHTNDTIGYETLKNLPGVEIARIDTNDTWARDFGAISIENHGVLECLDFGFNGWGLKYPSNLDNRVNFKLKNLGFLKHPLKTMPYILEGGSIESDGAGSILTNTQCLLEKNRNPHLNQHEIENMLKKELGAKQVLWYSYGYLKGDDTNSHTDTLARFLDKDTIVYSACEDKNDEHYTALKKMQEELKTFKKPDKTPYKLIPLEIPKAIFDENQQRLPATYVNFLLCNDALIVPTYNDPKDALILETLKQHTPLEVIGVDCNTLIKQHGSLHCVTMQLY
>NC_017741.1|WP_001199225.1|43309_45619_-|carbamoyltransferase-HypF
MQYFNQTAWKLALCNDATLLNKITLFGVVQGVGMRPFIYTLAQKLELVGFVRNTQAALEIVLPAHKTESFLNALKKGLPPLALVEKIIISPYDKTLKSNGFRILESKNHPLNLLSQIPKDLGVCEDCLREIRDKNSPYFHYAFNSCAKCGARYSLLNALPYDRENSALKPFKLCEFCAFVYKDANNKRFHIQGISCKKCGITLSYKRFKNDDALLECAKDIQKGKIIALKGLGGFALLCDARNFQTIERLRLLKNRPLKPFALMFKDLNTAKQHAFLSVLECESLNSTSAPILLARKKPDTQLAPNIAKNSPFYGVILPYTPLHALLLDLLDFPIIFTSANFSSLPLASDEAEIDSLSFIFDFKLTHNRAIIHRIDDSIAQHVDNAIRPMRLARGFAPLYLTLPKRSNDSQKKILALGAEQKGHFSLLDSETSILLLSPFCGDLSVLENEKHFKETLNFFLKTYDFKPTILVCDKHQNYTTTQMACGFNTPLLQVQHHHAHFLASILDALLQDPHLNHPFIGIVWDGSGAYENKIYGAECFVGDFERIEETARFEEFLLLGGEKAIKEPKRLVLEIALKHQLNKLLKRVQKHFKEDELEIFQQMHDRGIQSIATNSIGRLFDIVAFSLDLVGTISFEAESGQVLENLALQSDEIAFYPFKIKNSVVCLKDFYQAFEKDLGVLEPERIAKKFFNSLVEIITALIAPFKEHVVVCSGGVFCNQLLCEQLAKRLRGLKRQYFFHKHFPPNDSSIPIGQALMAYFNPTIIKKG
>NC_017741.1|WP_000378782.1|42308_43307_-|hydrogenase-expression/formation-protein-HypE
MDSVTLACGNGGKETNALIERVFMPYLKEFIVAFDEDAPKFEASGEYCVSTDSFVITPLIFNGGDIGKLCVCGSANDVSVQGGEPLYLNMGFILEEGLEIPLLKQILQSIQKELLKANLKLLSLDTKVVPKGSVDKLFINTTCIGKTIKPGISSRHLKQDQAIIISDTIANHGASLFAMRHEIKLKTNLESDCQLLYPLLKPLFLSDLKIHALRDATRGGLASVLNEWANSSKVKIVIEEEKIPLKEETKGICEILGLEPYALANEGVFVLAINQKDAPKALEILKSNEKAKNACVIGGVFENPYPSVVLKNAWGFERILEMPEGELLPRIC
>NC_017741.1|WP_001002520.1|41098_42031_+|GDP-L-fucose-synthase
MNEIILITGAYGMVGQNTALYLKKNKPDVTLLTPKKSELYLLDKDNVQAYLKEYKPTGIIHCAGRVGGIVANMNDLSAYMVENLLMGLYLFSSALDLGVKKAINLASSCAYPKFAPNPLKESDLLNGSLEPTNEGYALAKLSVMKYCEYVSAEKGVFYKTLVPCNLYGEFDKFEEKIAHMIPGLIARMHTAKLKNEKEFAMWGDGTARREYLNAKDLARFISLAYENIASIPSVMNVGSGVDYSIEEYYKMVAQVLDYKGAFVKDLSKPVGMQQKLMDISKQKALKWELEIPLEQGIKEAYEYYLKLLEV
>NC_017741.1|WP_000659844.1|39960_41106_+|GDP-mannose-4,6-dehydratase
MKEKIALITGVTGQDGSYLAEYLLNLGYEVHGLKRRSSSINTSRIDHLYEDLHSEHKRRFFLHYGDMTDSSNLIHLIATTKPTEIYNLAAQSHVKVSFETPEYTANADGIGTLRILEAMRILGLEKKTRFYQASTSELYGEVLETPQNENTPFNPRSPYAVAKMYAFYITKNYREAYNLFAVNGILFNHESKVRGETFVTRKITRAASAIAYNLTDCLYLGNLDAKRDWGHAKDYVKMMHLMLQAPIPQDYVIATGKTTSVRDFVKMSFEFIGISLEFQNTGVKEIGLIKSVDEKRANALKLNLSHLKTGQIVVRIDERYFRPTEVDLLLGDPTKAEKELGWVREYDLKELVKDMLEYDLKECQKNLYLQDGGYILRNFYE
>NC_017741.1|WP_000628956.1|58476_59040_+|hypothetical-protein
MITKNAYAFVVIEEKVMAFKQDKGLIPIFEGFVPLKEGFLKHFKERCNLEFLESLDLLFLYDKPSAHEIFSLCKELKNSIWDRKLVVALVEALEGFKDWNLSLKIEDKRSNSLGNGAKKLLTNADLESSHQKIVIDSMKTYHQSQQEKYKRERGQVKETPAQTPPSYGGGSIRISGDKKPDSNEENF
>NC_017741.1|WP_000049126.1|59055_59316_+|hypothetical-protein
MSKVQMDTEEVREFVNHLERFKELLNDEVNGLSSHFNNLDSWQDARRDKFSEVLDNLKSTFNEFDEAAQEQIAWLKERIRVLEEDY
>NC_017741.1|WP_000447915.1|61089_61515_+|SMI1/KNR4-family-protein
METIPTNSELNWEFVEPLNDNALSGLEDQLKMGLSDAFKDFVKRSNYGFSQWRSFMVGNKSYTFKHVLNFNLEGKGLFIDFMKSLKEWLKPEEIIFANDGYGGYYLLNTASGVALFLDTDDGSKHALLHLKMFLKKLESRG
>NC_017741.1|WP_000491338.1|61516_61867_+|hypothetical-protein
MFSHKVYLEGCTLELRKICDDFAENAMQDDLGQKLRDEVLEDMLKIAHDLENLEQDTQYQRRRIDEQIEEAKSLMKKIDMNFHSQSEIDKLMREAKEHEKEANRRYDEYLKSKDKE
>NC_017741.1|WP_001099459.1|64359_65157_-|urease-accessory-protein-UreD
MNTYAQESKLRLKTKIGADGRCVIEDNFFTPPFKLMAPFYPKDDLAEIMLLAVSPGMMRGDAQDMQLNIGPNCKLRITSQSFEKIHNTEDGFASREMHIVVGENAFLDFAPFPLIPFENAHFKGNTTISLHSSSQLLYSEIIVAGRVARNELFQFNRLHTKISILQDEKPIYYDNTILDPKTTNLNNMCMFDGYTHYLNLVLVNCPIELSGVRECIGENEGVDGAVSEIASSHLCVKALAKGSEPLLHLREKIARSITQTITQKI
>NC_017741.1|WP_000238747.1|65156_65756_-|urease-accessory-protein-UreG
MVKIGVCGPVGSGKTALIEALTRHMSKDYDMAVITNDIYTKEDAEFMCKNSVMPRDRIIGVETGGCPHTAIREDASMNLEAVEEMHGRFPNLELLLIESGGDNLSATFNPELADFTIFVIDVAEGDKIPRKGGPGITRSDLLVINKIDLAPYVGADLKVMERDSKKMRGEKPFIFTNIRAKEGLDDVIAWIKRNALLED
>NC_017741.1|WP_080024735.1|65784_66501_-|urease-accessory-protein-UreF
MPPKTPKDNNAHVDNEFLILQVNDAVFPIGSYTHSFGLETYIQQKKVTNKESALEYLKANLSSQFLYTEMLSLKLTYESTLQQDLKKILGIEEIITLSTSPMELRLANQKLGNRFIKTLQAMNELDMGEFFNAYAQKTKDPTHATSYGVFAASLGIELKKALRHYLYAQTSNMVINCVKSVPLSQNDGQKILLSLQSPFNQLIEKTLELDESHLCVASVQNDIKAMQHESLYSRLYMS
>NC_017741.1|WP_000583051.1|66556_67069_-|urease-accessory-protein-UreE
MIIERLIGNLRDLNPLDFSVDYVDLEWFETRKKIARFKTRQGKDMAIRLKDAPKLGLSQGDILFKEEKEIIAVNILDSEVIHIQAKSVAEVAKICYEIGNRHAALYYGESQFEFKTPFEKPTLALLEKLGVQNHVLSSKLDSKDRLTVSMPHSEPNFKVSLASDFKVVMK
>NC_017741.1|WP_000901278.1|67070_67658_-|acid-activated-urea-channel
MLGLVLLYVGIVLISNGICGLTKVDPKSTAVMNFFVGGLSIVCNVVVITYSALNPTAPVEGAEDIAQVSHHLTSFYGPATGLLFGFTYLYAAINHTFGLDWRPYSWYSLFVAINTIPAAILSHYSDMLDDHKVLGITEGDWWAIIWLAWGVLWLTAFIENILKIPLGKFTPWLAIIEGILTAWIPAWLLFIQHWA
>NC_017741.1|WP_000724275.1|67850_69560_-|urease-subunit-beta
MKKISRKEYASMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIVDYTGIYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGGTGPADGTNATTITPGRRNLKFILRAAEEYSMNLGFLAKGNASNDASLADQIEAGAIGLKIHEDWGTTPSAINHALDVADKYDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTYHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMVCHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNFRIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFAHHGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNSETYHVFVDGKEVTSKPANKVSLAQLFSIF

Crispr_ID: NC_017741_1

• CRISPR_ID: NC_017741_1
• CRISPR_location: 55287-55436
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_017741_1

Consensus_repeat	Method
AGATAAAGACAATCTAACTAAAG	CRISPRCasFinder

spacers of NC_017741_1

>1.1|55310|19|NC_017741|CRISPRCasFinder
AAAACACACGCTTATTAGC
>1.2|55352|19|NC_017741|CRISPRCasFinder
AAAATACCGAATTGTTAAG
>1.3|55394|19|NC_017741|CRISPRCasFinder
AAAACACCGAGCTGAAAAC

CRISPR arrays and Neighbor proteins around NC_017741_1

CRISPR arrays

The CRISPR arrays of NC_017741_1

>merge|NC_017741|1|55287-55436|CRISPRCasFinder
TGAAAACGAAAATCTAATTAATGAAAACACACGCTTATTAGCATCAAAAGAACAGCTGACTAAAGAAAATACCGAATTGTTAAGAGAAAAAGACAATCTAATTAAAGAAAACACCGAGCTGAAAACAGACAAAGACAATCTAAACAATCA

>NC_017741|1|1|55287-55436|CRISPRCasFinder
TGAAAACGAAAATCTAATTAATG	AAAACACACGCTTATTAGC
ATCAAAAGAACAGCTGACTAAAG	AAAATACCGAATTGTTAAG
AGAAAAAGACAATCTAATTAAAG	AAAACACCGAGCTGAAAAC
AGACAAAGACAATCTAAACAATCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017741.1|WP_000848994.1|53628_53838_+|hypothetical-protein	unknown	unknown	unknown
NC_017741.1|WP_000491338.1|61516_61867_+|hypothetical-protein	unknown	unknown	unknown
NC_017741.1|WP_000614655.1|46602_47301_-|site-specific-DNA-methyltransferase	unknown	unknown	gnl|CDD|334588
NC_017741.1|WP_001199225.1|43309_45619_-|carbamoyltransferase-HypF	unknown	unknown	gnl|CDD|272929
NC_017741.1|WP_000238747.1|65156_65756_-|urease-accessory-protein-UreG	unknown	unknown	gnl|CDD|129208
NC_017741.1|WP_000827214.1|45558_46551_-|AguA-family-protein	unknown	unknown	gnl|CDD|225505
NC_017741.1|WP_001169360.1|49743_53301_-|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143443
NC_017741.1|WP_000049126.1|59055_59316_+|hypothetical-protein	unknown	unknown	gnl|CDD|377587
NC_017741.1|WP_000583051.1|66556_67069_-|urease-accessory-protein-UreE	unknown	unknown	gnl|CDD|237322
NC_017741.1|WP_000901278.1|67070_67658_-|acid-activated-urea-channel	unknown	unknown	gnl|CDD|259831
NC_017741.1|WP_000659844.1|39960_41106_+|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl|CDD|273644
NC_017741.1|WP_080024735.1|65784_66501_-|urease-accessory-protein-UreF	unknown	unknown	gnl|CDD|223900
NC_017741.1|WP_000724275.1|67850_69560_-|urease-subunit-beta	unknown	unknown	gnl|CDD|184438
NC_017741.1|WP_000992785.1|54377_55205_+|hypothetical-protein	unknown	unknown	gnl|CDD|275056
NC_017741.1|WP_000510289.1|48217_49717_-|sodium/proline-symporter-PutP	unknown	unknown	gnl|CDD|273981
NC_017741.1|WP_000447915.1|61089_61515_+|SMI1/KNR4-family-protein	unknown	unknown	gnl|CDD|378155
NC_017741.1|WP_000378782.1|42308_43307_-|hydrogenase-expression/formation-protein-HypE	unknown	unknown	gnl|CDD|273984
NC_017741.1|WP_001002520.1|41098_42031_+|GDP-L-fucose-synthase	unknown	unknown	gnl|CDD|187550
NC_017741.1|WP_000628956.1|58476_59040_+|hypothetical-protein	unknown	unknown	unknown
NC_017741.1|WP_001099459.1|64359_65157_-|urease-accessory-protein-UreD	unknown	unknown	gnl|CDD|223899

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017741.1|WP_000901278.1|67070_67658_-|acid-activated-urea-channel	gnl|CDD|259831	cd13404, UreI_AmiS_like, UreI/AmiS family, proton-gated urea channel and putative amide transporters. This family includes UreI proton-gated urea channels as well as putative amide transporters (AmiS of the amidase gene cluster). Helicobacter pylori UreI (HpUreI), a proton-gated inner membrane urea channel opens in acidic pH to allow urea influx to the cytoplasm. There urea is metabolized, producing NH3 and CO2, leading to buffering of the periplasm. This action is essential for the survival of H. pylori in the stomach, and has been identified as a mechanism that could be clinically targeted to prevent various illnesses associated with infection by H. pylori. UreI and the related amide channels (AmiS) appear to function as hexamers, and have 6 predicted transmembrane segments. UreI has also been shown have a lipid "plug" in the center of the hexamer. Urea enters at the periplasmic opening of UreI and must pass 2 constriction sites, one on each side of a conserved Glu (Glu 177, H. pylori numbering), to reach the cytoplasm. Urea/thiourea selectivity is diminished by mutation of a conserved Trp to Ala or Phe in constriction site 2 (cytoplasmic). Channel functionality is greatly diminished by mutation of a conserved Trp in constriction site 1 (periplasmic) and a conserved Tyr in constriction site 2, and to a lesser extent a conserved Phe in site 1. In the cytoplasm, urease hydrolyzes urea to form ammonia and carbamate, which decomposes to carbonic acid. UreI is fully open at pH 5.0 to facilitate urea influx, but closes at neutral pH, preventing over-alkalization. Glu 177 (H. pylori numbering) is present in urea channel proteins, but absent in the related amide channels, suggesting that it plays a role in urea specificity.	2.3886e-74
NC_017741.1|WP_000614655.1|46602_47301_-|site-specific-DNA-methyltransferase	gnl|CDD|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	3.28481e-58
NC_017741.1|WP_001199225.1|43309_45619_-|carbamoyltransferase-HypF	gnl|CDD|272929	TIGR00143, Carbamoyltransferase_HypF, [NiFe] hydrogenase maturation protein HypF. A previously described regulatory effect of HypF mutatation is attributable to loss of activity of a regulatory hydrogenase. A zinc finger-like region CXXCX(18)CXXCX(24)CXXCX(18)CXXC region further supported the regulatory hypothesis. However, more recent work (PUBMED:11375153) shows the direct effect is on the activity of expressed hydrogenases with nickel/iron centers, rather than on expression. [Protein fate, Protein modification and repair].	0
NC_017741.1|WP_000238747.1|65156_65756_-|urease-accessory-protein-UreG	gnl|CDD|129208	TIGR00101, Urease_accessory_protein_UreG, urease accessory protein UreG. This model represents UreG, a GTP hydrolase that acts in the assembly of the nickel metallocenter of urease. It is found only in urease-positive species, although some urease-positive species (e.g. Bacillus subtilis) lack this protein. A similar protein, hypB, is an accessory protein for expression of hydrogenase, which also uses nickel. [Central intermediary metabolism, Nitrogen metabolism].	2.71579e-140
NC_017741.1|WP_000827214.1|45558_46551_-|AguA-family-protein	gnl|CDD|225505	COG2957, COG2957, Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism].	0
NC_017741.1|WP_001169360.1|49743_53301_-|aldehyde-dehydrogenase-family-protein	gnl|CDD|143443	cd07125, ALDH_PutA-P5CDH, Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA. The proline catabolic enzymes of the aldehyde dehydrogenase (ALDH) protein superfamily, proline dehydrogenase and Delta(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH, (EC=1.5.1.12 )), catalyze the two-step oxidation of proline to glutamate; P5CDH catalyzes the oxidation of glutamate semialdehyde, utilizing NAD+ as the electron acceptor. In some bacteria, the two enzymes are fused into the bifunctional flavoenzyme, proline utilization A (PutA) These enzymes play important roles in cellular redox control, superoxide generation, and apoptosis. In certain prokaryotes such as Escherichia coli, PutA is also a transcriptional repressor of the proline utilization genes.	0
NC_017741.1|WP_000049126.1|59055_59316_+|hypothetical-protein	gnl|CDD|377587	pfam06013, WXG100, Proteins of 100 residues with WXG. ESAT-6 is a small protein appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. homologs have been detected in other Gram-positive bacterial species. It may represent a novel secretion system potentially driven by the pfam01580 domains in the YukA-like proteins.	0.00136638
NC_017741.1|WP_000583051.1|66556_67069_-|urease-accessory-protein-UreE	gnl|CDD|237322	PRK13261, ureE, urease accessory protein UreE; Provisional.	1.65726e-45
NC_017741.1|WP_000659844.1|39960_41106_+|GDP-mannose-4,6-dehydratase	gnl|CDD|273644	TIGR01472, GDP-mannose_46_dehydratase_1, GDP-mannose 4,6-dehydratase. Alternate name: GDP-D-mannose dehydratase. This enzyme converts GDP-mannose to GDP-4-dehydro-6-deoxy-D-mannose, the first of three steps for the conversion of GDP-mannose to GDP-fucose in animals, plants, and bacteria. In bacteria, GDP-L-fucose acts as a precursor of surface antigens such as the extracellular polysaccharide colanic acid of E. coli. Excluded from this model are members of the clade that score poorly because of highly dervied (phylogenetically long-branch) sequences, e.g. Aneurinibacillus thermoaerophilus Gmd, described as a bifunctional GDP-mannose 4,6-dehydratase/GDP-6-deoxy-D-lyxo-4-hexulose reductase (PUBMED:11096116). [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NC_017741.1|WP_080024735.1|65784_66501_-|urease-accessory-protein-UreF	gnl|CDD|223900	COG0830, UreF, Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones].	8.54453e-94
NC_017741.1|WP_000724275.1|67850_69560_-|urease-subunit-beta	gnl|CDD|184438	PRK13985, ureB, urease subunit alpha.	0
NC_017741.1|WP_000992785.1|54377_55205_+|hypothetical-protein	gnl|CDD|275056	TIGR04211, hypothetical_protein, SH3 domain protein. Members of this protein family have a signal peptide, a strongly conserved SH3 domain, a variable region, and then a C-terminal hydrophobic transmembrane alpha helix region.	1.69842e-08
NC_017741.1|WP_000510289.1|48217_49717_-|sodium/proline-symporter-PutP	gnl|CDD|273981	TIGR02121, Osmoregulated_proline_transporter, sodium/proline symporter. This family consists of the sodium/proline symporter (proline permease) from a number of Gram-negative and Gram-positive bacteria and from the archaeal genus Methanosarcina. Using the related pantothenate permease as an outgroup, candidate sequences from Bifidobacterium longum and several from archaea are found to be outside the clade defined by known proline permeases. These sequences, scoring between 570 and -40, define the range between trusted and noise cutoff scores. [Transport and binding proteins, Amino acids, peptides and amines].	0
NC_017741.1|WP_000447915.1|61089_61515_+|SMI1/KNR4-family-protein	gnl|CDD|378155	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1). Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.	6.57565e-07
NC_017741.1|WP_000378782.1|42308_43307_-|hydrogenase-expression/formation-protein-HypE	gnl|CDD|273984	TIGR02124, Hydrogenase_expression/formation_protein_HypE, hydrogenase expression/formation protein HypE. This family contains HypE (or HupE), a protein required for expression of catalytically active hydrogenase in many systems. It appears to be an accessory protein involved in maturation rather than a regulatory protein involved in expression. HypE shows considerable homology to the thiamine-monophosphate kinase ThiL (TIGR01379) and other enzymes.	5.19443e-172
NC_017741.1|WP_001002520.1|41098_42031_+|GDP-L-fucose-synthase	gnl|CDD|187550	cd05239, GDP_FS_SDR_e, GDP-fucose synthetase, extended (e) SDRs. GDP-fucose synthetase (aka 3, 5-epimerase-4-reductase) acts in the NADP-dependent synthesis of GDP-fucose from GDP-mannose. Two activities have been proposed for the same active site: epimerization and reduction. Proteins in this subgroup are extended SDRs, which have a characteristic active site tetrad and an NADP-binding motif, [AT]GXXGXXG, that is a close match to the archetypical form. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.99375e-140
NC_017741.1|WP_001099459.1|64359_65157_-|urease-accessory-protein-UreD	gnl|CDD|223899	COG0829, UreH, Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones].	2.38528e-106

Protein sequences

>NC_017741.1|WP_000992785.1|54377_55205_+|hypothetical-protein
MNALKNSQQVLENEKAELKTEKDNLTKANAELKTEKERLTKEKTELTEKNKELDDQVGLLKGQIKSLEQSQQVLKNENTDLDNKITDLSKENQNLTKEKTELTEKNQKLTTEKDNLTTDLSNAKIQAIQANQEKDKLEQKHAPYKKLEKLYEVFLEVKGCLNFNFVEKTHSAMDLIASVLSDSKYYLESLYNKASQELSDRKSDKGEKLAELFDLLFEYVKDNKFERLKEPSAYDPTCKKLYPEQNTSGKMQRVVLIGYTYDKKTTHYTIVDMGS
>NC_017741.1|WP_000848994.1|53628_53838_+|hypothetical-protein
MKTIKNGIMIGTLGALLLSGCSSFDAQRFACLPKDHSLKDASTKKEVQYTPKGFFDPYSSNLNHWDSTF
>NC_017741.1|WP_001169360.1|49743_53301_-|aldehyde-dehydrogenase-family-protein
MQKIIDDSLELAKKLQDSISNHLSEQEKAFHSKMQKLLNNPENKVMLIELMDRSFRCLDNKARFEMIEHVLDKYKSREIFSSFEKLLLMGFLSFGKMLPDMSVPFFVNKIRSDTKAMVLDQEESQLKERILKRKNEKIILNVNFIGEEVLGEEEASARFEKYSQALKSNYIQYISIKITTIFSQINILDFEYSKKEIVKRLDALYALALEEEKKQGMPKFINLDMEEFRDLELTVESFMESIAKFDLNAGIVLQAYIPDSYEYLKKLHAFSKERVLKGLKPIKIRFVKGANMESEETIASVKDWALPTFSNKQDTDSNYNKMLDFVLEGDNYKYIHIGAASHNIFEIAYVYTRIHALNDPVVLEHFSFEMLEGMSLQASQELKEMHKLILYAPVCDEAHFNNAIAYLVRRLDENTSSDNFMKAFFNLKVGTSEWEDQEQRFLNSLKGIATLDNATHRTQDRNAKQSGHTTYPNHSFKNESDTDFILKANREWAKKVREKMHNAPILELYPEMDGRFEDPNLTPLEVFDKIHHKKIASVHLADREAILKALEVAKSDKNRFSQKSFTEIHALMSQTAQIFRERRGDLIGISALEVGKTFAETDAEVSEAIDFLEFYPYSLRVLQEQNKKTKFTPKGVGVVIAPWNFPVGISVGTIAAPLAAGNRVIYKPSSLSSVTGYKLCECFWDAGVPRDALIYLPSKGSDISEHLLKDESIKFAILTGGEDTAYKMLEANPTLALSAETGGKNATIVSKMADRDQAIKNVIHSAFSNSGQKCSATSLLVLEKEVYEDENFKKTLIDATLSLSVGDPFDFKNKIGTLADKPNEKVIKAIDELKSYENYEIPVSFVNDNPYLMKPSIKYGTKKGDFTHQTELFTPILSVMKAQDLDEAIDIVNSTGYGLTSALESLDEREWEYYLKRIEAGNIYINKPTTGAIVLRQPFGGVKKSAVGFGRKVGIFNYITQFVNIHQEEEDENALKNPLSEALEGLTQKGYDEHTHELRRAIFMAKSYAYHYKHEFSQAKDYVKIRGEDNLFSYTKVKSVGYRITEKDTLSDMLGVALACLISQIPLTLSIENERANKDLSFFLECLKALRANAPIVYESLQKFSEKLNAFNRVRYLKSDLDLLHEQASALGIVLATAKPCLNGRFELLYYHLERSVSISYHRYGNLGSRVLRQPTCHKSCCAEK
>NC_017741.1|WP_000510289.1|48217_49717_-|sodium/proline-symporter-PutP
MGHVVLSTPIVTMFVAYSLLMLYIGFYFYRQNETTADYFLGDRSMGPIISALSAGASDMSGWLLMGLPGALYVGGLINSHIAIGLSLGALINWVFVAKRLRIYTSVIANSITISDYFETRFSDDKHILRLISAFVILIFFIFYISSGLVSGAKLFEATFGIQYTYALSIGTLIIVSYTFLGGYKAVCWTDLIQGLLMMSALIVVPIVMIIHLGGIGEGIKIIREIKPENLSFLQGSSMVAIISSLAWGLGYFGQPHILVRFMSIRSIKDVPKATTIGISWMVISLIGACVMGLLGVAYAHKFDLSLEDPEKIFIVMSQLLFNPWITGILLSAILAAVMSTASSQLLVSSSTIAEDFYATIFNKDAPQKLVMVISRLSVLGVACIAFFISTDRNASILSIVSYAWAGFGASFGSVILFSLFWSRMTRIGAIAGMLSGASTVILYDKFGKSFLDIYEIVPGFIVASIAIVVFSLFSSVRAGTKEAFETMLKEIKEIESLKY
>NC_017741.1|WP_000614655.1|46602_47301_-|site-specific-DNA-methyltransferase
MIQIHHANAFEIIKDFYQQNLKVDAIITDPPYNISVKNNFSTLKSAKRQGIDFGEWDKNFRLLEWIKRYAPLVNPNGCMVIFCSYRFISYIVDFLEENGFVVKDFIQWVKNNPMPRNINRRYVQDTEFALWAVKKKAKWVFNKPKNEKYLRPLILKSPVVGGLERVKHPTQKSLALMEKIISIHTNPNDIVLDPFMGSGTTGLACKHLKRNFIGIESEREYFQIAKKRLNLF
>NC_017741.1|WP_000827214.1|45558_46551_-|AguA-family-protein
MKRMLAEFEKIQAILMAFPHEFGDWAYCIKEARESFLNIIQTIAKHAKVLVCVHTNDTIGYETLKNLPGVEIARIDTNDTWARDFGAISIENHGVLECLDFGFNGWGLKYPSNLDNRVNFKLKNLGFLKHPLKTMPYILEGGSIESDGAGSILTNTQCLLEKNRNPHLNQHEIENMLKKELGAKQVLWYSYGYLKGDDTNSHTDTLARFLDKDTIVYSACEDKNDEHYTALKKMQEELKTFKKPDKTPYKLIPLEIPKAIFDENQQRLPATYVNFLLCNDALIVPTYNDPKDALILETLKQHTPLEVIGVDCNTLIKQHGSLHCVTMQLY
>NC_017741.1|WP_001199225.1|43309_45619_-|carbamoyltransferase-HypF
MQYFNQTAWKLALCNDATLLNKITLFGVVQGVGMRPFIYTLAQKLELVGFVRNTQAALEIVLPAHKTESFLNALKKGLPPLALVEKIIISPYDKTLKSNGFRILESKNHPLNLLSQIPKDLGVCEDCLREIRDKNSPYFHYAFNSCAKCGARYSLLNALPYDRENSALKPFKLCEFCAFVYKDANNKRFHIQGISCKKCGITLSYKRFKNDDALLECAKDIQKGKIIALKGLGGFALLCDARNFQTIERLRLLKNRPLKPFALMFKDLNTAKQHAFLSVLECESLNSTSAPILLARKKPDTQLAPNIAKNSPFYGVILPYTPLHALLLDLLDFPIIFTSANFSSLPLASDEAEIDSLSFIFDFKLTHNRAIIHRIDDSIAQHVDNAIRPMRLARGFAPLYLTLPKRSNDSQKKILALGAEQKGHFSLLDSETSILLLSPFCGDLSVLENEKHFKETLNFFLKTYDFKPTILVCDKHQNYTTTQMACGFNTPLLQVQHHHAHFLASILDALLQDPHLNHPFIGIVWDGSGAYENKIYGAECFVGDFERIEETARFEEFLLLGGEKAIKEPKRLVLEIALKHQLNKLLKRVQKHFKEDELEIFQQMHDRGIQSIATNSIGRLFDIVAFSLDLVGTISFEAESGQVLENLALQSDEIAFYPFKIKNSVVCLKDFYQAFEKDLGVLEPERIAKKFFNSLVEIITALIAPFKEHVVVCSGGVFCNQLLCEQLAKRLRGLKRQYFFHKHFPPNDSSIPIGQALMAYFNPTIIKKG
>NC_017741.1|WP_000378782.1|42308_43307_-|hydrogenase-expression/formation-protein-HypE
MDSVTLACGNGGKETNALIERVFMPYLKEFIVAFDEDAPKFEASGEYCVSTDSFVITPLIFNGGDIGKLCVCGSANDVSVQGGEPLYLNMGFILEEGLEIPLLKQILQSIQKELLKANLKLLSLDTKVVPKGSVDKLFINTTCIGKTIKPGISSRHLKQDQAIIISDTIANHGASLFAMRHEIKLKTNLESDCQLLYPLLKPLFLSDLKIHALRDATRGGLASVLNEWANSSKVKIVIEEEKIPLKEETKGICEILGLEPYALANEGVFVLAINQKDAPKALEILKSNEKAKNACVIGGVFENPYPSVVLKNAWGFERILEMPEGELLPRIC
>NC_017741.1|WP_001002520.1|41098_42031_+|GDP-L-fucose-synthase
MNEIILITGAYGMVGQNTALYLKKNKPDVTLLTPKKSELYLLDKDNVQAYLKEYKPTGIIHCAGRVGGIVANMNDLSAYMVENLLMGLYLFSSALDLGVKKAINLASSCAYPKFAPNPLKESDLLNGSLEPTNEGYALAKLSVMKYCEYVSAEKGVFYKTLVPCNLYGEFDKFEEKIAHMIPGLIARMHTAKLKNEKEFAMWGDGTARREYLNAKDLARFISLAYENIASIPSVMNVGSGVDYSIEEYYKMVAQVLDYKGAFVKDLSKPVGMQQKLMDISKQKALKWELEIPLEQGIKEAYEYYLKLLEV
>NC_017741.1|WP_000659844.1|39960_41106_+|GDP-mannose-4,6-dehydratase
MKEKIALITGVTGQDGSYLAEYLLNLGYEVHGLKRRSSSINTSRIDHLYEDLHSEHKRRFFLHYGDMTDSSNLIHLIATTKPTEIYNLAAQSHVKVSFETPEYTANADGIGTLRILEAMRILGLEKKTRFYQASTSELYGEVLETPQNENTPFNPRSPYAVAKMYAFYITKNYREAYNLFAVNGILFNHESKVRGETFVTRKITRAASAIAYNLTDCLYLGNLDAKRDWGHAKDYVKMMHLMLQAPIPQDYVIATGKTTSVRDFVKMSFEFIGISLEFQNTGVKEIGLIKSVDEKRANALKLNLSHLKTGQIVVRIDERYFRPTEVDLLLGDPTKAEKELGWVREYDLKELVKDMLEYDLKECQKNLYLQDGGYILRNFYE
>NC_017741.1|WP_000628956.1|58476_59040_+|hypothetical-protein
MITKNAYAFVVIEEKVMAFKQDKGLIPIFEGFVPLKEGFLKHFKERCNLEFLESLDLLFLYDKPSAHEIFSLCKELKNSIWDRKLVVALVEALEGFKDWNLSLKIEDKRSNSLGNGAKKLLTNADLESSHQKIVIDSMKTYHQSQQEKYKRERGQVKETPAQTPPSYGGGSIRISGDKKPDSNEENF
>NC_017741.1|WP_000049126.1|59055_59316_+|hypothetical-protein
MSKVQMDTEEVREFVNHLERFKELLNDEVNGLSSHFNNLDSWQDARRDKFSEVLDNLKSTFNEFDEAAQEQIAWLKERIRVLEEDY
>NC_017741.1|WP_000447915.1|61089_61515_+|SMI1/KNR4-family-protein
METIPTNSELNWEFVEPLNDNALSGLEDQLKMGLSDAFKDFVKRSNYGFSQWRSFMVGNKSYTFKHVLNFNLEGKGLFIDFMKSLKEWLKPEEIIFANDGYGGYYLLNTASGVALFLDTDDGSKHALLHLKMFLKKLESRG
>NC_017741.1|WP_000491338.1|61516_61867_+|hypothetical-protein
MFSHKVYLEGCTLELRKICDDFAENAMQDDLGQKLRDEVLEDMLKIAHDLENLEQDTQYQRRRIDEQIEEAKSLMKKIDMNFHSQSEIDKLMREAKEHEKEANRRYDEYLKSKDKE
>NC_017741.1|WP_001099459.1|64359_65157_-|urease-accessory-protein-UreD
MNTYAQESKLRLKTKIGADGRCVIEDNFFTPPFKLMAPFYPKDDLAEIMLLAVSPGMMRGDAQDMQLNIGPNCKLRITSQSFEKIHNTEDGFASREMHIVVGENAFLDFAPFPLIPFENAHFKGNTTISLHSSSQLLYSEIIVAGRVARNELFQFNRLHTKISILQDEKPIYYDNTILDPKTTNLNNMCMFDGYTHYLNLVLVNCPIELSGVRECIGENEGVDGAVSEIASSHLCVKALAKGSEPLLHLREKIARSITQTITQKI
>NC_017741.1|WP_000238747.1|65156_65756_-|urease-accessory-protein-UreG
MVKIGVCGPVGSGKTALIEALTRHMSKDYDMAVITNDIYTKEDAEFMCKNSVMPRDRIIGVETGGCPHTAIREDASMNLEAVEEMHGRFPNLELLLIESGGDNLSATFNPELADFTIFVIDVAEGDKIPRKGGPGITRSDLLVINKIDLAPYVGADLKVMERDSKKMRGEKPFIFTNIRAKEGLDDVIAWIKRNALLED
>NC_017741.1|WP_080024735.1|65784_66501_-|urease-accessory-protein-UreF
MPPKTPKDNNAHVDNEFLILQVNDAVFPIGSYTHSFGLETYIQQKKVTNKESALEYLKANLSSQFLYTEMLSLKLTYESTLQQDLKKILGIEEIITLSTSPMELRLANQKLGNRFIKTLQAMNELDMGEFFNAYAQKTKDPTHATSYGVFAASLGIELKKALRHYLYAQTSNMVINCVKSVPLSQNDGQKILLSLQSPFNQLIEKTLELDESHLCVASVQNDIKAMQHESLYSRLYMS
>NC_017741.1|WP_000583051.1|66556_67069_-|urease-accessory-protein-UreE
MIIERLIGNLRDLNPLDFSVDYVDLEWFETRKKIARFKTRQGKDMAIRLKDAPKLGLSQGDILFKEEKEIIAVNILDSEVIHIQAKSVAEVAKICYEIGNRHAALYYGESQFEFKTPFEKPTLALLEKLGVQNHVLSSKLDSKDRLTVSMPHSEPNFKVSLASDFKVVMK
>NC_017741.1|WP_000901278.1|67070_67658_-|acid-activated-urea-channel
MLGLVLLYVGIVLISNGICGLTKVDPKSTAVMNFFVGGLSIVCNVVVITYSALNPTAPVEGAEDIAQVSHHLTSFYGPATGLLFGFTYLYAAINHTFGLDWRPYSWYSLFVAINTIPAAILSHYSDMLDDHKVLGITEGDWWAIIWLAWGVLWLTAFIENILKIPLGKFTPWLAIIEGILTAWIPAWLLFIQHWA
>NC_017741.1|WP_000724275.1|67850_69560_-|urease-subunit-beta
MKKISRKEYASMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIVDYTGIYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGGTGPADGTNATTITPGRRNLKFILRAAEEYSMNLGFLAKGNASNDASLADQIEAGAIGLKIHEDWGTTPSAINHALDVADKYDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTYHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMVCHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNFRIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFAHHGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNSETYHVFVDGKEVTSKPANKVSLAQLFSIF

Crispr_ID: NC_017741_3

• CRISPR_ID: NC_017741_3
• CRISPR_location: 396410-396522
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017741_3

Consensus_repeat	Method
GAGAGGCTCTCTAGCGTTACTGAAGAAAT	CRISPRCasFinder

spacers of NC_017741_3

>3.1|396439|55|NC_017741|CRISPRCasFinder
TATCGCCAAAAAGCAAGAAGAAACCCAACGCCAAGAAGCCCCAGAGGATACGCAT

CRISPR arrays and Neighbor proteins around NC_017741_3

CRISPR arrays

The CRISPR arrays of NC_017741_3

>merge|NC_017741|3|396410-396522|CRISPRCasFinder
GAGAGGCTCTCTAGCGTTACTGAAGAAATTATCGCCAAAAAGCAAGAAGAAACCCAACGCCAAGAAGCCCCAGAGGATACGCATGAGAGGCTCTCTAGCGTTACTGAAGAAAT

>NC_017741|3|3|396410-396522|CRISPRCasFinder
GAGAGGCTCTCTAGCGTTACTGAAGAAAT	TATCGCCAAAAAGCAAGAAGAAACCCAACGCCAAGAAGCCCCAGAGGATACGCAT
GAGAGGCTCTCTAGCGTTACTGAAGAAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017741.1|WP_000364762.1|401752_403456_+|flagellar-basal-body-M-ring-protein-FliF	unknown	unknown	gnl|CDD|129310
NC_017741.1|WP_001019023.1|392540_393347_+|septum-site-determining-protein-MinD	unknown	unknown	gnl|CDD|225447
NC_017741.1|WP_000840094.1|393588_394389_+|DNA-protecting-protein-DprA	unknown	unknown	gnl|CDD|273238
NC_017741.1|WP_000810779.1|397611_399162_-|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl|CDD|273193
NC_017741.1|WP_000056306.1|404492_405269_+|flagellar-assembly-protein-FliH	unknown	unknown	gnl|CDD|235850
NC_017741.1|WP_001207777.1|391529_392522_+|ketol-acid-reductoisomerase	unknown	unknown	gnl|CDD|235491
NC_017741.1|WP_000833938.1|389565_390504_-|tetraacyldisaccharide-4'-kinase	unknown	unknown	gnl|CDD|224577
NC_017741.1|WP_000603059.1|405265_407122_+|1-deoxy-D-xylulose-5-phosphate-synthase	unknown	unknown	gnl|CDD|129308
NC_017741.1|WP_000742581.1|389090_389633_+|UDP-4-amino-4,-6-dideoxy-N-acetyl-beta-L-altrosamine-N-acetyltransferase	unknown	unknown	gnl|CDD|274661
NC_017741.1|WP_000599165.1|394385_394790_+|Holliday-junction-resolvase-RuvX	unknown	unknown	gnl|CDD|234639
NC_017741.1|WP_000373227.1|399171_400788_-|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl|CDD|235437
NC_017741.1|WP_000201851.1|403474_404506_+|flagellar-motor-switch-protein-FliG	unknown	unknown	gnl|CDD|272961
NC_017741.1|WP_001117116.1|396730_397612_-|RluA-family-pseudouridine-synthase	unknown	unknown	gnl|CDD|223638
NC_017741.1|WP_000862787.1|408935_409865_+|DNA-cytosine-methyltransferase	unknown	unknown	gnl|CDD|273211
NC_017741.1|WP_000051411.1|393343_393577_+|cell-division-topological-specificity-factor-MinE	unknown	unknown	gnl|CDD|188120
NC_017741.1|WP_001168078.1|390500_391283_-|NAD+-synthase	unknown	unknown	gnl|CDD|184435
NC_017741.1|WP_080024689.1|388200_389094_+|CMP-N-acetylneuraminic-acid-synthetase	unknown	unknown	gnl|CDD|226488
NC_017741.1|WP_000699918.1|395691_396030_+|hypothetical-protein	unknown	unknown	gnl|CDD|235969
NC_017741.1|WP_000838000.1|407118_408927_+|elongation-factor-4	unknown	unknown	gnl|CDD|235462
NC_017741.1|WP_000829951.1|401046_401709_+|hypothetical-protein	unknown	unknown	gnl|CDD|239486

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017741.1|WP_000364762.1|401752_403456_+|flagellar-basal-body-M-ring-protein-FliF	gnl|CDD|129310	TIGR00206, Flagellar_M-ring_protein, flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF). Component of the M (cytoplasmic associated) ring, one of four rings (L,P,S,M) which make up the flagellar hook-basal body which is a major portion of the flagellar organelle. Although the basic structure of the flagella appears to be similar for all bacteria, additional rings and structures surrounding the basal body have been observed for some bacteria (eg Vibrio cholerae and Treponema pallidum). [Cellular processes, Chemotaxis and motility].	0
NC_017741.1|WP_001019023.1|392540_393347_+|septum-site-determining-protein-MinD	gnl|CDD|225447	COG2894, MinD, Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning].	3.39811e-149
NC_017741.1|WP_000840094.1|393588_394389_+|DNA-protecting-protein-DprA	gnl|CDD|273238	TIGR00732, Protein_smf, DNA protecting protein DprA. Disruption of this gene in both Haemophilus influenzae and Helicobacter pylori drastically reduces the efficiency of transformation with exogenous DNA, but with different levels of effect on chromosomal (linear) and plasmid (circular) DNA. This difference suggests the DprA is not active in recombination, and it has been shown not to affect DNA binding, leaving the intermediate step in natural transformation, DNA processing. In Strep. pneumoniae, inactivation of dprA had no effect on the uptake of DNA. All of these data indicated that DprA is required at a later stage in transformation. Subsequently DprA and RecA were both shown in S. pneumoniae to be required to protect incoming ssDNA from immediate degradation. Role of DprA in non-transformable species is not known. The gene symbol smf was assigned in E. coli, but without assignment of function. [Cellular processes, DNA transformation].	4.21561e-94
NC_017741.1|WP_000810779.1|397611_399162_-|single-stranded-DNA-specific-exonuclease-RecJ	gnl|CDD|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_017741.1|WP_000056306.1|404492_405269_+|flagellar-assembly-protein-FliH	gnl|CDD|235850	PRK06669, fliH, flagellar assembly protein H; Validated.	6.91442e-66
NC_017741.1|WP_001207777.1|391529_392522_+|ketol-acid-reductoisomerase	gnl|CDD|235491	PRK05479, PRK05479, ketol-acid reductoisomerase; Provisional.	4.31554e-180
NC_017741.1|WP_000833938.1|389565_390504_-|tetraacyldisaccharide-4'-kinase	gnl|CDD|224577	COG1663, LpxK, Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane].	1.15482e-89
NC_017741.1|WP_000603059.1|405265_407122_+|1-deoxy-D-xylulose-5-phosphate-synthase	gnl|CDD|129308	TIGR00204, 1-deoxy-D-xylulose-5-phosphate_synthase, 1-deoxy-D-xylulose-5-phosphate synthase. DXP synthase is a thiamine diphosphate-dependent enzyme related to transketolase and the pyruvate dehydrogenase E1-beta subunit. By an acyloin condensation of pyruvate with glyceraldehyde 3-phosphate, it produces 1-deoxy-D-xylulose 5-phosphate, a precursor of thiamine diphosphate (TPP), pyridoxal phosphate, and the isoprenoid building block isopentenyl diphosphate (IPP). [Biosynthesis of cofactors, prosthetic groups, and carriers, Other, Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine, Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	0
NC_017741.1|WP_000742581.1|389090_389633_+|UDP-4-amino-4,-6-dideoxy-N-acetyl-beta-L-altrosamine-N-acetyltransferase	gnl|CDD|274661	TIGR03585, PseH, UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase. Sequences in this family are members of the pfam00583 (GNAT) superfamily of acetyltransferases and are proposed to perform a N-acetylation step in the process of pseudaminic acid biosynthesis in Campylobacter species. This gene is commonly observed in apparent operons with other genes responsible for the biosynthesis of pseudaminic acid and as a component of flagellar and exopolysaccharide biosynthesis loci. Significantly, many genomes containing other components of this pathway lack this gene, indicating that some other N-acetyl transferases may be incolved and/or the step is optional, resulting in a non-acetylated pseudaminic acid variant sugar.	5.70554e-60
NC_017741.1|WP_000599165.1|394385_394790_+|Holliday-junction-resolvase-RuvX	gnl|CDD|234639	PRK00109, PRK00109, Holliday junction resolvase RuvX.	2.45801e-37
NC_017741.1|WP_000373227.1|399171_400788_-|CTP-synthase-(glutamine-hydrolyzing)	gnl|CDD|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NC_017741.1|WP_000201851.1|403474_404506_+|flagellar-motor-switch-protein-FliG	gnl|CDD|272961	TIGR00207, Flagellar_motor_switch_protein_FliG, flagellar motor switch protein FliG. The fliG protein along with fliM and fliN interact to form the switch complex of the bacterial flagellar motor located at the base of the basal body. This complex interacts with chemotaxis proteins (eg CHEY). In addition the complex interacts with other components of the motor that determine the direction of flagellar rotation. The model contains putative members of the fliG family at scores of less than 100 from Agrobacterium radiobacter and Sinorhizobium meliloti as well as fliG-like genes from treponema pallidum and Borrelia burgdorferi. That is why the suggested cutoff is set at 20 but was set at 100 to construct the family. [Cellular processes, Chemotaxis and motility].	2.15549e-164
NC_017741.1|WP_001117116.1|396730_397612_-|RluA-family-pseudouridine-synthase	gnl|CDD|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	3.2745e-67
NC_017741.1|WP_000862787.1|408935_409865_+|DNA-cytosine-methyltransferase	gnl|CDD|273211	TIGR00675, Modification_methylase, DNA-methyltransferase (dcm). All proteins in this family for which functions are known are DNA-cytosine methyltransferases. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	7.95862e-114
NC_017741.1|WP_000051411.1|393343_393577_+|cell-division-topological-specificity-factor-MinE	gnl|CDD|188120	TIGR01215, Cell_division_topological_specificity_factor, cell division topological specificity factor MinE. This protein is involved in the process of cell division. This protein prevents the proteins MinC and MinD to inhibit cell division at internal sites, but allows inhibiton at polar sites. This allows for correct cell division at the proper sites. [Cellular processes, Cell division].	5.17489e-25
NC_017741.1|WP_001168078.1|390500_391283_-|NAD+-synthase	gnl|CDD|184435	PRK13980, PRK13980, NAD synthetase; Provisional.	5.40125e-121
NC_017741.1|WP_080024689.1|388200_389094_+|CMP-N-acetylneuraminic-acid-synthetase	gnl|CDD|226488	COG3980, spsG, Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase [Cell envelope biogenesis, outer membrane].	3.21551e-102
NC_017741.1|WP_000699918.1|395691_396030_+|hypothetical-protein	gnl|CDD|235969	PRK07213, PRK07213, chlorohydrolase; Provisional.	0.00856174
NC_017741.1|WP_000838000.1|407118_408927_+|elongation-factor-4	gnl|CDD|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NC_017741.1|WP_000829951.1|401046_401709_+|hypothetical-protein	gnl|CDD|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	1.34738e-15

Protein sequences

>NC_017741.1|WP_000699918.1|395691_396030_+|hypothetical-protein
MKIMHQVMDFLDSCKQTIQKNSNEALQKTKRALFKEKSQKIREQAVKIVEKRLKKEGMKLSDFNEEELKIMFEAEEKRLLEQIHAKESEENQEKSVKHFKEVWEKGDNEQER
>NC_017741.1|WP_000599165.1|394385_394790_+|Holliday-junction-resolvase-RuvX
MILACDVGLKRIGIAALLNGVILPLEAILRHNRNQASRDLSDLLREKNIQVLVVGKPNESYADTNARIEHFIKLLDFKGEIVFINEDRSSIEAYENLGHLGKKNKRLAIKDGRLDSLSACRILERYCQQVLKKC
>NC_017741.1|WP_000840094.1|393588_394389_+|DNA-protecting-protein-DprA
MKSNFQYSALENIPKAFDILKDPPKKLYCVGDTKLLDAPLKVAIIGTRRPTPYSKQHTITLAREFAKNGAVIVSGGALGVDIIAQENALPKTIMLSPCSLDFIYPTNNHKVIQEIAQNGLILSEYEKDFMPVKGSFLARNRLVIALSDAVIIPQADLKSGSMSSARLAQKYQKPLFVLPQRLNESDGTNELLEKGQAQGIFNIQNFINTLLKDHHLKEMPEIKDEFLEYCAKNPSYEEAYLKFGDKLLEYELLGKIKRINHIVVLA
>NC_017741.1|WP_000051411.1|393343_393577_+|cell-division-topological-specificity-factor-MinE
MSLFDFFKNKGSAATATDRLKLILAKERTLNLPYMEEMRKEIIAVIQKYTKSSDIHFKTIDGNQSVETIEVEIILPK
>NC_017741.1|WP_001019023.1|392540_393347_+|septum-site-determining-protein-MinD
MAIVVTITSGKGGVGKSTTAANLAIGLAESGKKVVAVDFDIGLRNLDMILGLENRIVYDVVDVMEKNCNLSQALITDKKTKNLSFLAASQSKDKNVLDKEKVAILINALRADFDYILIDSPAGIESGFEHAILHADMALVVVTPEVSSLRDSDRVIGIIDAKSNRAKKGMEVHKHLIINRLKPELVANGEMISIEEVLKILCLPLIGIIPEDSHIISATNKGEPVIRTDCESAKAYQRITRRILGEEVEYVEFKAKKGFFSALKGIFS
>NC_017741.1|WP_001207777.1|391529_392522_+|ketol-acid-reductoisomerase
MALPVYYDKDIDLGVIQSLQVGIIGYGAQGEAQALNLRDSKVRVRIGLYQGSLSASKAKAEGFEVLEVKELVQQSDVIMALLPDELHKEVLEKEVIPFLKEGQIVGFAHGFSVHFNQVVLPKGVGAILVAPKGPGSALREEYLKNRGLYHLIAIEQESSKNNAKAVALSYAKAMGGGRMGVLETSFKEECESDLFGEQAVLCGGLEAIVRTGFETLIRAGYPEELAYFECVHEVKLVADLLHYKGVEGLRKHISNTAEFGAIKNREPMGNLLEKRMQKILKKIQNGSFAKDFLLEKSLNYPRLNTERKALKETKIEQIGEILRAPFNHKK
>NC_017741.1|WP_001168078.1|390500_391283_-|NAD+-synthase
MQKDHQKLIAYLCDFLEKEAQKRGFKKVVYGLSGGLDSAVVGVLCQKVFKKNAHALLMPSLVSMPESKTDALDLCETFSIPYTEYSIAPYDAIFDSHFKDASLTRKGNFCARLRMAFLYDYSLKSDSLVIGTSNKSERMLGYGTLFGDLACAINPIGELFKTEVYELACHLNIPKKILNKPPSADLFVGQSDEKDLGYPYSVIDPLLKDIEALFQNKPIDAETLTQLGYDEILVKNIMSRIQKNSFKLELPTIAKRFNPK
>NC_017741.1|WP_000833938.1|389565_390504_-|tetraacyldisaccharide-4'-kinase
MKSDKPFLERYFYDPTLLQKGLIFALYPFSLIYQGIATLKRKTAKKHDFKIPIISVGNLIAGGSGKTPFILETAPRYQEVAVISRGYQRDSKGLVVVSVKGNILVSQQTAGDEAYLLALNLKQASVIVSEKRELGVLKALELGAKIVFLDDGFRFNFNQFNLLLKPKVPPYYPFCLPSGLYRESIKSYKEAHLVITEDKDYKRITSISHPTKRMLLATAIANPSRLDAFLPKEVVKKLYFRDHAPFDLKLLEKEFYQNNATSLLVTSKDLVKLQDCNLPLSVLDLKLEICPKVLEQIDRYILSYPCNTKEHL
>NC_017741.1|WP_000742581.1|389090_389633_+|UDP-4-amino-4,-6-dideoxy-N-acetyl-beta-L-altrosamine-N-acetyltransferase
MKKNYCYKNIQAIDFAHLNDEEKLLVLEFRNHPNTALWMYSAFISLKTHLQFIEDLKNSPNHRYFLFKEEGVYLGVGSITKINFFHKHGYLGIYKNPFLKNRGETILKALERIAFEEFQLNSLHLEVMENNFKAIAFYEKNHYELEGRLKGFVSKEKEFIDVLLYYKDKKGYNDRSVLKL
>NC_017741.1|WP_080024689.1|388200_389094_+|CMP-N-acetylneuraminic-acid-synthetase
MQPFEKRMPVKILCDCFLTSGLGHVRRCEKILSFIEKLGVKADLYLYKHNNISAFLEGVGNDDFLIIDSYCLNSKDFYLLKEKAKSLMVIEDKEHVKGFYPKNTKIMNFTLNALKHYHYLSKDYQYYLGVGFYPVDIRFVYERPINTENKEVLITLGGSEQKTLKEIVKILENKGMHLHIISPHIPKNPPKNTHYYSPLSPLEFSSLMKFCACAISAAGQTLYELALSQTPSLIIPIASNQIIQSQEFESLGIFKQTSLKTLAKDFEKLQIQKNQAWAKNLAFGSELEGALREFLEI
>NC_017741.1|WP_001117116.1|396730_397612_-|RluA-family-pseudouridine-synthase
MPFVEEEFEILKPTKALFFVLDVLKCSLKEAQRHLDKQRLKQNQQAVRKSQMIQGVVSLIHFKPNEKTQALVFETKDFGVFDKPPQVYTHPKGYFYHESLLDYIQSHFGKNAHPAHRLDYETSGLVLAGKTLQSAKDLKALFMQKKVKKTYLALVHGLVDKNIVIDKPILTLQSIQKDLRIRSKISPLGKPSTTLVEPLSYNPFLDISLLKITPLTGRTHQIRLHLSSVGHRIVGEGLYGVIDENAREYLQLKRENNTPLLMLHASSLAFEFKGAIHEITSPMPKRFMPFLKD
>NC_017741.1|WP_000810779.1|397611_399162_-|single-stranded-DNA-specific-exonuclease-RecJ
MKQKLKAQIKERVASIAYNEKGFPSPFLFKDLKKAALKIIEAMRANTEILVVGDYDADGVISSTIMAKFFESLNYKHVRIVIPNRFIDGYGISKKFLEKHHAPLIITVDNGISAFEAARFCKEKNYTLIITDHHCLHHDEVPDAYAVINPKQPDCDFIQKEVCGALVAFYLCYGIHQLLGKEKSHSSELLCLAGVATIADMMPLTFFNRFLVSKALYFLQKESLGAMGFLRQREVFRKRSLKASDISFSIAPLINSAGRMQDAKMALDFLSANNFQDGYFLYERLKACNMKRKMIQQQVFEEAFKHAMVGEKIIIAFKDDWHEGVLGIVASKLVEATQKPSLVFTFKEGVYKGSGRSSSNIDLIDALNGVSSLLLGYGGHRQACGLSVGKNNIISLFETLENFDFKILPFCEKEPPLTLTLKDIDRELLEIIEAGEPYGQENPEPLFQAQNLEVIEEKIIKESHQVLRFKDKECIKEAIYFNTERFLKAGEKVNAIFSVELDECSNEPKMFVKSLL
>NC_017741.1|WP_000373227.1|399171_400788_-|CTP-synthase-(glutamine-hydrolyzing)
MDRAKFIFVTGGVLSSLGKGISSSSIATLLQHCNYQVSILKIDPYINIDPGTMSPLEHGEVFVTSDGAETDLDIGHYERFLNRNLTRLNNFTTGQIFSSVIENERKGEYLGKTIQIVPHVTDEIKRRIKSAAKGLDFLIVEVGGTVGDMEGMFYLEAIRQLKLELGNEKVINVHVTLIPYIQTTNELKTKPTQHSVQELRRLGVTPQIILARSPKPLDKELKNKIALSCDVEQDSVIVATDTKSIYACPILFLQEGILTPIARRFNLNKLHPKMAAWNTLVEKIIAPKHKVKIGFVGKYLSLKESYKSLIEALIHAGAHLDTQVNIEWLDSENFNEKTDLEGVDAVLVPGGFGERGIEGKICAIQRARLEKLPFLGICLGMQLAIIEFCRNVLGLKGANSTEFNQRCEYPVVYLIEDFIDQNHQKQVRTYNSPLGGTMRLGEYECEIVPNSLLEKAYKKPSIKERHRHRYEINPKYRQEWENKGLKVVGFGANHLIEAIELDDHPFFVGVQFHPEFTSRLQSPNPIILDFIKSALHKS
>NC_017741.1|WP_000829951.1|401046_401709_+|hypothetical-protein
MAENSFKNVTIQSKPFFLSQVKTLFLLGGVFSAFFILMVGLVFFDCVNSMDNAIFNLMRSNSSNPILDQTLQRIVFLGSSQFVLPLSLLVGVFLSLYRRNLALGVWFVLSVILFEALLESLKHLLAHSIQWLSHSANFPNATALSLALFYGLLVLLIPHLITHQTLKNILSYSLFGLILLIGLALIVLGVSFSSVLGGFCLGALGACFSIGIYLSVFQKI
>NC_017741.1|WP_000364762.1|401752_403456_+|flagellar-basal-body-M-ring-protein-FliF
MDLKVLLQRIVDFFIKLNKKQKIALIAAGVLITALLVFLLLYPFKEKDYTQGGYGVLFERLDSSDNALILQHLQQNQIPYKILKDDTILIPKDKVYEERITLASQGIPKTSKVGFEIFDTKDFGATDFDQNIKLIRAIEGELSRTIESLNPILKANVHIAIPKDSVFVAKEVPPSASVMLKLKPDMKLSPTQILGIKNLIAAAVPKLTTENVKIVNENGESIGEGDILENSKELALEQLRYKQNFENILENKIVNILAPIVGGKNKVVARVNAEFDFSQRKSTKETFDPNNVVRSEQNLEEKKEGAPKKQVGGVPGVVSNIGPVQGLKDNKEPEKYEKSQNTTNYEVGKTISEIKGEFGTLVRLNAAVVVDGKYKIALKDGANTLEYEPLSDESLKKINALVKQAIGYNQNRGDDVAVSNFEFNPMAPMLDNATLSEKIMHKTQKILGSFTPLIKYILVFIVLFIFYKKVIVPFSERMLEVVPDEDKEVKSMFEEMDEEEDELNKLGDLRKKVEDQLGLNATFSEEEVRYEIVLEKIRGTLKERPDEIAMLFKLLIKDEISSDSAKG
>NC_017741.1|WP_000201851.1|403474_404506_+|flagellar-motor-switch-protein-FliG
MATKLTPKQKAQLDELSMSEKIAILLIQVGEDTTGEILRHLDIDSITEISKQIVQLNGTDKQIGAAVLEEFFAIFQSNQYINTGGLEYARELLTRTLGSEEAKKVMDKLTKSLQTQKNFAYLGKIKPQQLADFIINEHPQTIALILAHMEAPNAAETLSYFPDEMKAEISIRMANLGEISPQVVKRVSTVLENKLESLTSYKIEVGGLRAVAEIFNRLGQKSAKTTLARIESVDNKLAGAIKEMMFTFEDISKLDNFAIREILKVADKKDLSLALKTSTQDLTDKFLNNMSSRAAEQFIEEMQYLGAVKIKDVDVAQRKIIEIVQSLQEKGVIQTGEEEDVIE
>NC_017741.1|WP_000056306.1|404492_405269_+|flagellar-assembly-protein-FliH
MSLNSRKNLIQKDHLNKHDIQKYEFKSMANLPPTTNPNGASLETPNPEEPLEKKAIENDLIDCLLKKTDELSSHLVKLQMQFEKAQEESKALIENAKNDGYKIGFKEGEEKMRNELTHSVNEEKNQLLHAITALDEKMKKSEDHLMALEKELSAIAIDIAKEVILKEVEDNSQKVALALAEELLKNVLDATDIHLKVNPLDYPYLNERLQNASKIKLESNEAISKGGVMITSSNGNLDGNLMERFKTLKESVLENFKV
>NC_017741.1|WP_000603059.1|405265_407122_+|1-deoxy-D-xylulose-5-phosphate-synthase
MILQNKTFDLNPNDIAGLELVCQTLRSRILEVVSANGGHLSSSLGAVELIVSMHALFDCQKNPFIFDTSHQAYAHKLLTGRFESFSTLRQFKGLSGFTKPSESAYDYFIAGHSSTSVSIGVGVAKAFCLKQALGMPIALLGDGSISAGIFYEALNELGDRKYPMIMILNDNEMSISTPIGALSKALSQLMKGPFYQSFRSKVKKILNTLPESVNYLASRFEESFKLITPGVFFEELGINYIGPINGHDLSAIIETLKLAKELKEPVLIHAQTLKGKGYKIAEGRYEKWHGVGPFDLDTGLSKKSKSAILSPTEAYSNTLLELAKKDEKIVGVTAAMPSGTGLDKLIDTYPLRFFDVAIAEQHALTSSSAMAKEGFKPFVSIYSTFLQRAYDSIVHDACISSLPIKLAIDRAGIVGEDGETHQGLLDVSYLRSIPNMVIFAPRDNETLKNAVHFANEHHSSPCAFRYPRGSFALKEGVFEPSGFVLGQSELLKKEGEILLIGYGNGVGRAYLVQLALKEKNIECALLDLRFLKPLDQNLSAIIAPYQKLYVFSDNYKLGGVASAILEFLSEQNILKPVKSFEIIDEFIMHGNTALVEKSLGLDTESLTDAILKDLGQER
>NC_017741.1|WP_000838000.1|407118_408927_+|elongation-factor-4
MKSKVPMKNIRNFSIIAHIDHGKSTLADCLIAECNAISNREMTSQVMDTMDIEKERGITIKAQSVRLNYTLKGEDYVLNLIDTPGHVDFSYEVSRSLCSCEGALLVVDATQGVEAQTIANVYIALDNHLEILPVINKIDLPNANVLEVKQDIEDTIGIDCSSANEVSAKARLGIKDLLEKIITTIPAPSGDFNAPLKALIYDSWFDNYLGALALVRIMDGSINTEQEILVMGTGKKHGVLGLYYPNPLKKIPTKSLECGEIGIVSLGLKSVTDIAVGDTLTDAKNPTPKPIEGFMPAKPFVFAGLYPIETDRFEDLREALLKLQLNDCALNFEPESSVALGFGFRVGFLGLLHMEVIKERLEREFGLNLIATAPTVVYEVHLTDNSIKYVQNPSELPPENHIACIKEPFVRATIITPSEFLGNLMQLLNNKRGIQEKMEYLNQSRVMLTYSLPSNEIVMDFYDKLKSCTKGYASFDYEPIENREAHLVKLDVRVAGDVVDALSIIIDKNKAYEKGRALVETMKELIPRQLFEVAIQASVGNKIIARETIKSVGKNVTAKCYGGDITRKRKLLEKQKEGKKRMKAIGKVELPQEAFLAILKID
>NC_017741.1|WP_000862787.1|408935_409865_+|DNA-cytosine-methyltransferase
MKVGSLFAGIGGFECAFLQAGFEIGWANELDKDACNTYRANFKHKLLEQDIKDLNPNELEDVGLISAGFPCQAFSIAGLQKGLNDERGAIVMEMFRIIQAKKPQVLLLENVKNLVSHNKGETLKFILETLKNLGYFVHYKILNTYEYSTVPQNRERIYIIGFLDKNHYKRFHFPLKINHTQSIKDLLEIKVGEEFYYKQYRFYETLKKEITKRDTCYQWRRHYVRENKNNLCPTLTANMGTGGHNVPLVLDEQGIRKLTPKECLNFQGFAKDYVLPNTAKSKLYKQIGNSVSVPVIKALALEIKKVVYG

Crispr_ID: NC_017741_4

• CRISPR_ID: NC_017741_4
• CRISPR_location: 890404-890684
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_017741_4

Consensus_repeat	Method
GAGAAAAAAGAATGCGAGAAATTACTCACGCCTGAAGCGAAAAAACTTTTAGAAGAAGAAGC	PILER-CR

spacers of NC_017741_4

>4.1|890466|55|NC_017741|PILER-CR
CAAAGAGAGCGTTAAAGCTTATTTGGATTGCGTATCTCAAGCCAAAACTGAAGCT
>4.2|890583|56|NC_017741|PILER-CR
CTAAAAAAAGCGTTAAGGCTTATTTGGACTGCGTTTCAAGAGCTAGGAATGAAAAA

CRISPR arrays and Neighbor proteins around NC_017741_4

CRISPR arrays

The CRISPR arrays of NC_017741_4

>merge|NC_017741|4|890404-890684|PILER-CR
TGTGAGAAATTACTCACGCCTGAAGCGAAAAAACTTTTAGAAGAAGAAGCCAAAGAGAGCGTTAAAGCTTATTTGGATTGCGTATCTCAAGCCAAAACTGAAGCTGAGAAAAAAGAATGCGAGAAATTACTCACGCCTGAAGCGAAAAAAAAGTTAGAAGAAGCTAAAAAAAGCGTTAAGGCTTATTTGGACTGCGTTTCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTACTCACGCCTGAAGCGAAAAAGCTTTTAGAGCAACAAGC

>NC_017741|4|1|890404-890684|PILER-CR
TGTGAGAAATTACTCACGCCTGAAGCGAAAAAACTTTTAGAAGAAGAAGCCAAAGAGAGCGT	TAAAGCTTATTTGGATTGCGTATCTCAAGCCAAAACTGAAGCTGAGAAAAAAGAA
TGCGAGAAATTACTCACGCCTGAAGCGAAAAAAAAGTTAGAAGAAGCTAAAAAAAGCGTTAA	GGCTTATTTGGACTGCGTTTCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCG
AGAAATTACTCACGCCTGAAGCGAAAAAGCTTTTAGAGCAACAAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017741.1|WP_000835485.1|876587_877508_-|cag-pathogenicity-island-type-IV-secretion-system-protein-CagN	unknown	unknown	unknown
NC_017741.1|WP_041199800.1|879075_879420_+|cag-pathogenicity-island-protein-CagP	unknown	unknown	unknown
NC_017741.1|WP_000433953.1|886711_888280_+|type-IV-secretion-system-apparatus-protein-CagX	unknown	unknown	gnl|CDD|226035
NC_017741.1|WP_000418800.1|893974_894574_+|cag-pathogenicity-island-translocation-protein-CagZ	unknown	unknown	gnl|CDD|72471
NC_017741.1|WP_001292863.1|903502_904834_-|HslU--HslV-peptidase-ATPase-subunit	unknown	unknown	gnl|CDD|235364
NC_017741.1|WP_000879910.1|877522_878653_-|type-IV-secretion-system-apparatus-protein-CagM	unknown	unknown	unknown
NC_017741.1|WP_000722726.1|901608_902601_-|flagellin-deglycosylation-protein	unknown	unknown	gnl|CDD|225577
NC_017741.1|WP_000471654.1|900708_901539_+|sel1-repeat-family-protein	unknown	unknown	gnl|CDD|223861
NC_017741.1|WP_000776469.1|882509_883352_-|type-IV-secretion-system-apparatus-protein-CagT	unknown	unknown	gnl|CDD|372486
NC_017741.1|WP_000133872.1|894578_895571_+|cag-pathogenicity-island-type-IV-secretion-system-ATPase	unknown	unknown	gnl|CDD|274301
NC_017741.1|WP_080024710.1|902597_903506_-|GTPase-Era	unknown	unknown	gnl|CDD|224081
NC_017741.1|WP_001000464.1|883367_884015_-|cag-pathogenicity-island-translocation-protein-CagU	unknown	unknown	unknown
NC_017741.1|WP_080024708.1|880387_880768_-|cag-pathogenicity-island-protein	unknown	unknown	unknown
NC_017741.1|WP_000900772.1|884288_885047_+|cag-pathogenicity-island-type-IV-secretion-system-protein-CagV	unknown	unknown	gnl|CDD|226259
NC_017741.1|WP_000462184.1|897938_898448_-|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl|CDD|374577
NC_017741.1|WP_000069564.1|881713_882313_+|cag-pathogenicity-island-protein-CagS	unknown	unknown	gnl|CDD|374741
NC_017741.1|WP_000785738.1|900130_900478_-|cag-pathogenicity-island-protein-Cag1	unknown	unknown	unknown
NC_017741.1|WP_000481889.1|885051_886659_+|cag-pathogenicity-island-translocation-protein-CagW	unknown	unknown	unknown
NC_017741.1|WP_000467129.1|898457_899903_-|type-IV-secretion-system-apparatus-protein-Cag3	unknown	unknown	gnl|CDD|273066
NC_017741.1|WP_000389375.1|895579_897826_+|cag-pathogenicity-island-type-IV-secretion-system-protein-Cag5	unknown	unknown	gnl|CDD|226036

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017741.1|WP_000389375.1|895579_897826_+|cag-pathogenicity-island-type-IV-secretion-system-protein-Cag5	gnl|CDD|226036	COG3505, VirD4, Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion].	0
NC_017741.1|WP_000433953.1|886711_888280_+|type-IV-secretion-system-apparatus-protein-CagX	gnl|CDD|226035	COG3504, VirB9, Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion].	1.44232e-62
NC_017741.1|WP_000418800.1|893974_894574_+|cag-pathogenicity-island-translocation-protein-CagZ	gnl|CDD|72471	pfam09053, CagZ, CagZ. CagZ is a 23 kDa protein consisting of a single compact L-shaped domain, composed of seven alpha-helices that run antiparallel to each other. 70% of the residues are in alpha-helix conformation and no beta-sheet is present. CagZ is essential for the translocation of the pathogenic protein CagA into host cells.	1.35853e-122
NC_017741.1|WP_001292863.1|903502_904834_-|HslU--HslV-peptidase-ATPase-subunit	gnl|CDD|235364	PRK05201, hslU, ATP-dependent protease ATPase subunit HslU.	0
NC_017741.1|WP_000471654.1|900708_901539_+|sel1-repeat-family-protein	gnl|CDD|223861	COG0790, COG0790, FOG: TPR repeat, SEL1 subfamily [General function prediction only].	9.06153e-14
NC_017741.1|WP_000776469.1|882509_883352_-|type-IV-secretion-system-apparatus-protein-CagT	gnl|CDD|372486	pfam13117, Cag12, Cag pathogenicity island protein Cag12. This is a Proteobacterial family of Cag pathogenicity island proteins.	5.77573e-28
NC_017741.1|WP_000133872.1|894578_895571_+|cag-pathogenicity-island-type-IV-secretion-system-ATPase	gnl|CDD|274301	TIGR02788, conjugal_transfer_protein, P-type DNA transfer ATPase VirB11. The VirB11 protein is found in the vir locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for DNA transfer. VirB11 is believed to be an ATPase. VirB11 is a homolog of the P-like conjugation system TrbB protein and the Flp pilus sytem protein TadA.	6.75492e-144
NC_017741.1|WP_080024710.1|902597_903506_-|GTPase-Era	gnl|CDD|224081	COG1159, Era, GTPase [General function prediction only].	3.37932e-123
NC_017741.1|WP_000900772.1|884288_885047_+|cag-pathogenicity-island-type-IV-secretion-system-protein-CagV	gnl|CDD|226259	COG3736, VirB8, Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion].	2.66351e-68
NC_017741.1|WP_000462184.1|897938_898448_-|transglycosylase-SLT-domain-containing-protein	gnl|CDD|374577	pfam16494, Na_Ca_ex_C, C-terminal extension of sodium/calcium exchanger domain. Na_Ca_ex_C is a region of the higher eukaryote sodium/calcium exchanger domain that extends toward the C-terminal, and is cytoplasmic.	0.00878873
NC_017741.1|WP_000069564.1|881713_882313_+|cag-pathogenicity-island-protein-CagS	gnl|CDD|374741	pfam16707, CagS, Cag pathogenicity island protein S of Helicobacter pylori. CagS is a family of proteins from the pathogenicity island of Helicobacter pylori. The gene lies just downstream of the cluster whose protein-products resemble those of the Vibrio proteins that form the structural core of T4SS. The exact function of CagS is not known.	1.85963e-110
NC_017741.1|WP_000467129.1|898457_899903_-|type-IV-secretion-system-apparatus-protein-Cag3	gnl|CDD|273066	TIGR00414, Serine--tRNA_ligase, seryl-tRNA synthetase. This model represents the seryl-tRNA synthetase found in most organisms. This protein is a class II tRNA synthetase, and is recognized by the pfam model tRNA-synt_2b. The seryl-tRNA synthetases of two archaeal species, Methanococcus jannaschii and Methanobacterium thermoautotrophicum, differ considerably and are included in a different model. [Protein synthesis, tRNA aminoacylation].	0.00775488
NC_017741.1|WP_000722726.1|901608_902601_-|flagellin-deglycosylation-protein	gnl|CDD|225577	COG3034, COG3034, Uncharacterized protein conserved in bacteria [Function unknown].	1.28809e-104

Protein sequences

>NC_017741.1|WP_000433953.1|886711_888280_+|type-IV-secretion-system-apparatus-protein-CagX
MEQAFFKKIIGCFCLGYLFLSSVIEAATPEIKNFNRGRVKVVNKKIAYLGDEKPITIWTSLDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTRDYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSEFIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQAEETIKQRAKDKINIKTDKPQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHEVSSVIEGELKKREEAKRQRELIKQENLNTTAYINRVMMASNEQIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIFDDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIKDKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK
>NC_017741.1|WP_000481889.1|885051_886659_+|cag-pathogenicity-island-translocation-protein-CagW
MFNIKRTFLITIISFFLIVPNWLKAIDLPIVSNLKIYQTVYCMLIPSYVLTNKSFADILTGYTSIGASGSGKSSGQGVIEALSAPLATSLAASNLVKYLNTLGPLWGSAWASVATAIQGFALTPSGGCNFGWNALINKNIDVSMDSMLDNLSNKIRNFTKGGVEDNVKGNVLLQIIGSITAQVSTNITADGLIWLIGKEFTANKLQNNTTAMLAFAALESIVKGADVAVLPAYGVVNLPDIIIGQGSYLDFVSYLIYIVFGIFVFISFMKLRDISNNIQINIGFEYMRFVGGTLFKMAMVSFIAYAGFGYLYKISYSIYFGLAGAFGLNQTLFWALDLVLNYTVNSILPAVRAVFSNVGNNAPSLLQGLQVAGISLFAIFMQVTVIMRISTVVVKPLIAGAFSGIVFPIAVCLIVLDWFKDSMKNILIWFINNLFILVLAIPILLFGVLALLAFNLTITPSAAIQNINQGGLGIDSTLASLITLFILKGFIETIIESVNAIVNTIFSSVSMDGSRMDRERDALMVGKVGGSMFKR
>NC_017741.1|WP_000900772.1|884288_885047_+|cag-pathogenicity-island-type-IV-secretion-system-protein-CagV
MLGKKNEEVLIDENLVGGVIALDRLAKLNKANRTFKRAFYLSMALNIATVTSIVMMMPLKKTDIFVYGIDRYTGEFKIVKRSDARQIVNSEAVVDSATSKFVSLLFGYSKNSLRDRKDQLMQYCDVSFQTQAMRMFNENIRQFVDKVRAEAIISSNIRREKVKNSPLTRLTFFITIKITPDTMENYEYITKKEVTIYYDFASGNSSQENLIINPFGFKVFDIQITDLQNEQTVSEILRKIKEVESKNKALKK
>NC_017741.1|WP_001000464.1|883367_884015_-|cag-pathogenicity-island-translocation-protein-CagU
MNDTTEHHGSNSLNAPSPSNSQSNDLLNLLDSLYPKGSLGEQRFHEALKNQEELKNILIEIEKLPQEKRYELLMQIGQAKQRIMEAYAHSFLGYIGGLEHLLGLCMGGIFVLFAIYFVFLRTSKNTDLVESLKTKLKLQYFYYAFGVGAVLFFGLETIRSIYELYILGIGSTNDKVLFVLKNICFIGMGYLIYKVIKVIGIKNFIYGLFTSKKQE
>NC_017741.1|WP_000776469.1|882509_883352_-|type-IV-secretion-system-apparatus-protein-CagT
MKLRASVLIGATILCLTLSACSNYAKKVVKQKNHVYTPVYNELIEKYSEIPLNDKLKDTPFMVQVKLPNYKDYLLDNKQVVLTFKLVHHSKKITLIGDANKILQYKNYFQANGARSDIDFYLQPTLNQKGVVMIASNYNDNPNNKEQPQTFDVLQGSQPMLGANTKNLHGYDVSGANNKQVINEVAREKAQLEKINQYYKMLLQDKEQEYTTRKNNQREILETLSNRAGYQMRQNVISSEIFKNGNLNMQTKEEEVREKLQEERENEYLRNQIRSLLSGK
>NC_017741.1|WP_000069564.1|881713_882313_+|cag-pathogenicity-island-protein-CagS
MSNNMRKLFSMIADSKDKKEKLIESLQENELLNTDEKKKIIDQIKTMHDFFKQIHTNKGALDKVLRNYMKDYRAVIKSIGVDKFKKVYRLLESETMELLCAIAKNPNFLFSKFDRSILGIFLPFFSKPIMFKMSIREMDSQIELYGTKLPLLKLFVMTDEEVNFYANLKTIEQYNDYVRDLLMKFDLEKYMKEKGVQNA
>NC_017741.1|WP_080024708.1|880387_880768_-|cag-pathogenicity-island-protein
MLSAKTRIRTPSKRELVQPKIKGLIMGKILASLLGGGTNLFMGLSSDLFSMILNFLFFLMLMMGLNEILEKKFNLPMDNIKNFMTEVLKNGFGSMKNMGSALIGNGFSSSKSDKTANKMGVPQVKL
>NC_017741.1|WP_041199800.1|879075_879420_+|cag-pathogenicity-island-protein-CagP
MKQPISKLKQNFLQFKHSFNKHLDKYSLYYRLFNISSIVIGFLIGLFSYGAGVILVYPILFLFALITKPSFFYYTTYLLLLVSLSAISKYYLLSHANFTMKLIILMTQWQNWFL
>NC_017741.1|WP_000879910.1|877522_878653_-|type-IV-secretion-system-apparatus-protein-CagM
MLAKIVFSSLVAFGVLSANVEQFGSFFNEIKKEQEEVAAKEDALKARKKLLNNTHDFLEDLIFRKQKIKELVDHRAKVLLDLENKYKKEKEALEKETRGKILTAKSKAYGDLEQALKDNSLYKKLLPNPYAYVLNQETFTKEDKERLSYYYPQVKNSNIFKKTTATTKDKAQALLQMGVFSLDEEQNKKASRLALSYKQAIEEYSNNISNLLSRKELDNIDYYLQLERNKFDSKAKDIAQKATNTLIFNSERLAFSMAIDKINEKYLRGYEAFSNLLKNVKDDVELNTLTKNFTNQKLSFAQKQKLCLLVLDSFNFDTQSKKSILKKTNEYNIFVDSDPMMSDKTTMQKEHYKIFNFFKTVLSAYRNNVAKNNPFE
>NC_017741.1|WP_000835485.1|876587_877508_-|cag-pathogenicity-island-type-IV-secretion-system-protein-CagN
MKSIFKKLGSVALYFLVIYGGLNAINTALLPSEYKKLVALGFKKIKTLHQRHDDKEVTEEEKKFATNALREKLRNDRARAEQIQKNIEAFEKKNNSSIQKKATKHKGLQELNETNANPLNGNPNSNSSTETKSNKDDNFDEMINKVNEAFVKPATPLVPNEWRTPEIEAIINECIISSNDYDGLRKCLIKGIKDQKILAPLLEKIQEIETENNKFSRQHLSGLKLALNNSNNRTFLIASCAICEKRKKEMEQENNYQDTTNASEFGATDTKKNEAKDAAFSNNRSKSELPNSVINQIEQSIAHGKK
>NC_017741.1|WP_000418800.1|893974_894574_+|cag-pathogenicity-island-translocation-protein-CagZ
MELGFNEAERQKILDSNRSLMGNANEVRDKFIQNYATSLKDSNDPQDFLRRVQELRINMQKNFISFDAYYNYLNNLVLASYNRCKQEKTFAESTIKNELTLGEFVVEISDNFNNFMCDEVAKISDLVASYLPREYLPPFIDGNMMGVAFQILGIDDFGRKLNEIVQDIGTKYIILSKNKTYLTSLERAKLITQLKLNLE
>NC_017741.1|WP_000133872.1|894578_895571_+|cag-pathogenicity-island-type-IV-secretion-system-ATPase
MTEDRLSAEDKKFLEVERALKEAALNPLRHATEELFGDFLKMENITEICYNGNKVVWVLKNNGEWQPFDVRDKKAFSLSRLMHFARCCASFKKKTIDNYENPILSSNLANGERVQIVLSPVTVNDETISISIRIPSKTTYPHSFFEEQGFYNLLDNKEQAISAIKDGIAIGKNVIVCGGTGSGKTTYIKSIMEFIPKEERIISIEDTEEIVFKHHKNYTQLFFGGNITSADCLKSCLRMRPDRIILGELRSSEAYDFYNVLCSGHKGTLTTLHAGSSEEAFIRLANMSSSNNAARNIKFESLIEGFRDLIDMIVHINHHKQCDEFYIKHR
>NC_017741.1|WP_000389375.1|895579_897826_+|cag-pathogenicity-island-type-IV-secretion-system-protein-Cag5
MEDFLYNTLYFIENYKLVVIFSFIGLIALFFLYKFIKAQKKAFKDKANQPQKKKNFKEIIIEGLKERVKTFGFWLQAILLLSYSFITSGLFFLILLGNFYDDNKLPESDDDLFDIWIYAIQDFPAYYFKALCFSSLKIYGFNISLVVYSSILCSYIFITFFVWFLKYLTRTRDIGANKKVDDLFGSASWESEEKMIKAKLITPNNKKRAFDKREVIVGRRGLGDFIAYAGQAFIGLIAPTRSGKGVGFIMPNMINYPQNIVVFDPKADTMETCGKIREKRFNQKVYIYEPFSLKTHRFNPFAYVDFGNDVVLTEDILSQIDTRLKGHGMVASGGDFSTQIFGLAKLVFPERPNEKDPFFSNQARNLFVINCNIYRDLMWTKKGLEFVKRKKIIMPETPTMFFIGSMASGINLIDENTNMEKVVSLMEFFGGEEDKSGDNLRVLSPATRNMWNNFKTMGGAKETYSSVQGVYTSAFAPYNNAMIRNFTSANDFDFRRLRIDEVSIGVIANPKESTIVGPILELFFNVMIYSNLILPIHDPQCKRSCLMLMDEFTLCGYLETFVKAVGIMAEYNMRPAFVFQSKAQLENDPPLGYGRNGAKTILDNLSLNMYYGINNDNYYEHFEKLSKVLGKYTRQDVSRSIDDNTGKTNTSISNKERFLMTPDELMTMGDELIILENTLKPIKCHKALYYDDPFFTDELIKVSPSLSKKYKLGKVPNQATFYNDLQAAKTRGELSYDKSLVPVGSSEL
>NC_017741.1|WP_000462184.1|897938_898448_-|transglycosylase-SLT-domain-containing-protein
MFEKWIGLTLLLNSLAYPCQKVTISFKQYENLIHIHQKGCDNEVVCRTLISIALLESSLGLNNKREISLKDTSYSMFHITLNTAKKFYPTYSKTLLKYKLLNDVDFAISLAKRILKENFDYYKQKHPNKSVYQIVEMAVGAYNGGMKHNPNGAYVKRFRCIYSQVRYNG
>NC_017741.1|WP_000467129.1|898457_899903_-|type-IV-secretion-system-apparatus-protein-Cag3
MFGKLATAVSLIGLLTSNTLYAKEISEADKVIKATKETKETKKEAKRLKKEAKQRQQIPDHKKPQYASVDDTKTQALFDIYDTLNVNDKSFGDWFGNSALKDKTYLYAMDLLDYNNYLSIENPIIKTRAMGTYADLIIITGSLEQVNGYYNILKALNKRNAKFVLKINDNLPYAQATFLRVPKRSDPNAHTLDKGASIDENKLFEQQKRAYFNYANDVICRPNDEVCSPLRDEMVAMPTSDSATQKPNIIAPYSLYRLKETNNANEAQPSPYATQTAPENSKEKLIEELIANSQLIANEEEREKKLLAEKEKQEAELAKYKLKDLENQKKLKALEAELKKKNAKKPRVVEVPISPRTSNPDETMRVVKEKENYNGLLVDKETTIKRSYQGTLISENSYSKKTPINPNDLRSLEEEIKSYYIKSNGLCYANGISLYVKIKNDPYKEGMLCGYESVQNLLSPLKDKLKYDKQKLQKALLKDLK
>NC_017741.1|WP_000785738.1|900130_900478_-|cag-pathogenicity-island-protein-Cag1
MADTINTTEATHETKKPNAFVNFFKNNLADKRYDSLGLIGAGVLCCVLSGAIGIVGIIFVAIGIFLSFSNINLVKLVEKLFKKQSKVVTTVNNETQKSQATSVTNEPTEAKETKD
>NC_017741.1|WP_000471654.1|900708_901539_+|sel1-repeat-family-protein
MFKDFYRTTFSFLKPLLLLLCLLLPFSLHADSDDCRITCVWDQYAKEFKTNFCKFGLNNLNYGQYKQAFQFFRWAQEYGIGLGSVYLAKMYLEGKGVKADYKKVQLYAKNAIKGYGSGLLGGALILGRMQAEGLGMKKDLKQALNTYRQVLRVFSNKGINFHNNFRLPDLTEMTGMLIGARFIDLSSLNANPIKFEKQFANMVEFVSGIKNEPIVPYDVAEISSNIILLKQQMGEILYRIGIAYQEGLGTKKKKEKAKKFLQKSAEFGYEKAMEAL
>NC_017741.1|WP_000722726.1|901608_902601_-|flagellin-deglycosylation-protein
MKKILPALLMGFVGLNADERLLEIMRLYQKQGLEVVGQKLDSYLSDKSFWLEELQNKDTDFGYYQNKQFLFVADKSKPSLEFYEIESNMLKKINSSKALVGSKKGDKTLEGDLATPIGVYRITQKLERLDQYYGVLAFVTNYPNLYDTLKKRTGHGIWVHGMPLNGDRNELNTKGCIAIENPLLSSYDKALKGEKAFLITYEDKFFPSTKEELSMVLSSLFQWKEAWARGDFERYMRFYNPNFTRYDGMKFNAFKEYKKRVFAKNEKKNIAFSSISVIPYPNSQNKRLFYVVFDQDYKAYQQNKLSYSSNSQKELYVEIENNQVSIIMEK
>NC_017741.1|WP_080024710.1|902597_903506_-|GTPase-Era
MMKTKAGFVALIGKPNAGKSTLLNTLLNAHLALVSHKANATRKLMKCIVPFKDKEGYESQIIFLDTPGLHHQEKLLNQCMLSQALKAMGDAELCVFLASVHDDLKGYEEFLSLCQKPHILAVSKIDTATHKQVLQKLQEYQQHASQFLALVPLSAKKSQNLNALLECISKHLSPSAWLFEKDLMSDEKMRDIYKEIIRESLFDFLSDEIPYESDVMIDKFIEEERIDKVYAHIIVEKESQKKIVIGKNGVNIKRIGTNARLKMQEVGEKKVFLNLQVIAQKSWSKEEKSLQKLGYIHKRGMD
>NC_017741.1|WP_001292863.1|903502_904834_-|HslU--HslV-peptidase-ATPase-subunit
MSELNMTPREIVAYLDEYIIGQKEAKKSIAIAFRNRYRRLQLEKSLQEEITPKNILMIGSTGVGKTEIARRIAKIMKLPFVKVEASKYTEVGFVGRDVESMVRDLVNNSVLLVENEHKEKLKDKIEEAVIEKIAKKLLPPLPNGVSEEKKQEYANSLLKMQQRIAQGELDSREIEIEVRKKSIEIDSNVPPEILRVQENVIKFFHKEQDKVKKTLSVKEAKEALKAEISDTLLDGEAIKMEGLKRAESSGVIFIDEIDKIAVSSKEGGRQDPSKEGVQRDLLPIVEGSVVNTKYGPIKTEHILFIAAGAFHLSKPSDLIPELQGRFPLRVELESLTEEIMYMILTQTKTSIIKQYQALLKVEGVGIVFEDNAIKELAKLSYNANQKSEDIGARRLHTTIEKVLEDISFEAEDYSGQKVTITKELVQSKLGDLVADENLVKYIL

Crispr_ID: NC_017741_5

• CRISPR_ID: NC_017741_5
• CRISPR_location: 977541-977736
• CRISPR_type: Orphan
• Repeat_type: I-B
• Spacer_info: 3 spacers

Consensus repeat of NC_017741_5

Consensus_repeat	Method
TTCAATCAAGGGACTTATAACTTTA	PILER-CR
TTCAATCAAGGGACTTATAACTTTA	CRT

spacers of NC_017741_5

>5.1|977566|35|NC_017741|PILER-CR,CRT
GTAACAGCGCTAACTTAAGCTTCAACAACAGCACT
>5.2|977626|32|NC_017741|PILER-CR,CRT
ATAGCCTTCAATCCACTTTTAATAACAGCAAT
>5.3|977683|29|NC_017741|PILER-CR,CRT
CCGACAACGCCAGCTTCAATAACGACACC

CRISPR arrays and Neighbor proteins around NC_017741_5

CRISPR arrays

The CRISPR arrays of NC_017741_5

>merge|NC_017741|5|977541-977736|PILER-CR,CRT
TTCAATCAAGGGACTTATAACTTTAGTAACAGCGCTAACTTAAGCTTCAACAACAGCACTTTCAATCAAGGGACTTACAACTTTAATAGCCTTCAATCCACTTTTAATAACAGCAATTTCAATCAAGGGACTTATCATTTTACCGACAACGCCAGCTTCAATAACGACACCTTCAATCAAGGGACTTATAGCTTTA

>NC_017741|5|2|977541-977736|PILER-CR
TTCAATCAAGGGACTTATAACTTTA	GTAACAGCGCTAACTTAAGCTTCAACAACAGCACT
TTCAATCAAGGGACTTACAACTTTA	ATAGCCTTCAATCCACTTTTAATAACAGCAAT
TTCAATCAAGGGACTTATCATTTTA	CCGACAACGCCAGCTTCAATAACGACACC
TTCAATCAAGGGACTTATAGCTTTA

>NC_017741|5|1|977541-977736|CRT
TTCAATCAAGGGACTTATAACTTTA	GTAACAGCGCTAACTTAAGCTTCAACAACAGCACT
TTCAATCAAGGGACTTACAACTTTA	ATAGCCTTCAATCCACTTTTAATAACAGCAAT
TTCAATCAAGGGACTTATCATTTTA	CCGACAACGCCAGCTTCAATAACGACACC
TTCAATCAAGGGACTTATAGCTTTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017741.1|WP_001172978.1|983991_985089_+|Hop-family-outer-membrane-protein-HopJ/HopK	unknown	unknown	gnl|CDD|280099
NC_017741.1|WP_000592486.1|962983_964531_+|Hop-family-adhesin-AlpA	unknown	unknown	gnl|CDD|280099
NC_017741.1|WP_000894607.1|960139_962170_+|ATP-dependent-helicase	unknown	unknown	gnl|CDD|223288
NC_017741.1|WP_000041796.1|990407_991067_+|hypothetical-protein	unknown	unknown	unknown
NC_017741.1|WP_001126543.1|971498_974756_-|carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl|CDD|235393
NC_017741.1|WP_000426951.1|988141_988684_+|GTP-cyclohydrolase-I-FolE	unknown	unknown	gnl|CDD|129173
NC_017741.1|WP_001115888.1|985146_985353_-|4-oxalocrotonate-tautomerase-family-protein	unknown	unknown	gnl|CDD|129125
NC_017741.1|WP_001229979.1|971062_971494_-|hypothetical-protein	unknown	unknown	gnl|CDD|376519
NC_017741.1|WP_001064288.1|988699_989611_+|polyprenyl-synthetase-family-protein	unknown	unknown	gnl|CDD|223220
NC_017741.1|WP_000722482.1|989607_990411_+|5'/3'-nucleotidase-SurE	unknown	unknown	gnl|CDD|234732
NC_017741.1|WP_001240275.1|974850_975543_-|Bax-inhibitor-1/YccA-family-protein	unknown	unknown	gnl|CDD|198414
NC_017741.1|WP_000812605.1|964552_966136_+|Hop-family-adhesin-AlpB	unknown	unknown	gnl|CDD|280099
NC_017741.1|WP_000010356.1|977747_983939_+|toxin-like-outer-membrane-protein	unknown	unknown	gnl|CDD|227938
NC_017741.1|WP_080024749.1|958997_960146_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|223897
NC_017741.1|WP_001052413.1|986076_987222_+|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl|CDD|272903
NC_017741.1|WP_001099588.1|985498_986080_+|recombination-protein-RecR	unknown	unknown	gnl|CDD|273176
NC_017741.1|WP_080024713.1|968447_970136_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|366183
NC_017741.1|WP_001248492.1|966672_968211_-|outer-membrane-beta-barrel-protein-HofG	unknown	unknown	gnl|CDD|334957
NC_017741.1|WP_000688624.1|975686_976682_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|273675
NC_017741.1|WP_080024714.1|987160_988141_+|zinc-metalloprotease-HtpX	unknown	unknown	gnl|CDD|235081

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017741.1|WP_001172978.1|983991_985089_+|Hop-family-outer-membrane-protein-HopJ/HopK	gnl|CDD|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	3.33986e-47
NC_017741.1|WP_000592486.1|962983_964531_+|Hop-family-adhesin-AlpA	gnl|CDD|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	1.46103e-53
NC_017741.1|WP_000894607.1|960139_962170_+|ATP-dependent-helicase	gnl|CDD|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	3.59173e-137
NC_017741.1|WP_001126543.1|971498_974756_-|carbamoyl-phosphate-synthase-large-subunit	gnl|CDD|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0
NC_017741.1|WP_000426951.1|988141_988684_+|GTP-cyclohydrolase-I-FolE	gnl|CDD|129173	TIGR00063, GTP_cyclohydrolase_1, GTP cyclohydrolase I. alternate names: Punch (Drosophila),GTP cyclohydrolase I (EC 3.5.4.16) catalyzes the biosynthesis of formic acid and dihydroneopterin triphosphate from GTP. This reaction is the first step in the biosynthesis of tetrahydrofolate in prokaryotes, of tetrahydrobiopterin in vertebrates, and of pteridine-containing pigments in insects. [Biosynthesis of cofactors, prosthetic groups, and carriers, Folic acid].	2.62285e-105
NC_017741.1|WP_001115888.1|985146_985353_-|4-oxalocrotonate-tautomerase-family-protein	gnl|CDD|129125	TIGR00013, Probable_tautomerase_K2, 4-oxalocrotonate tautomerase family enzyme. 4-oxalocrotonate tautomerase is a homohexamer in which each monomer is very small, at about 62 amino acids. Pro-1 of the mature protein serves as a general base. The enzyme functions in meta-cleavage pathways of aromatic hydrocarbon catabolism. Because several Arg residues located near the active site in the crystal structure of Pseudomonas putida are not conserved among all members of this family, because the literature describes a general role in the isomerization of beta,gamma-unsaturated enones to their alpha,beta-isomers, and because of the presence of fairly distantly related paralogs in Campylobacter jejuni, the family is regarded as not necessarily uniform in function. [Energy metabolism, Other].	4.5194e-26
NC_017741.1|WP_001229979.1|971062_971494_-|hypothetical-protein	gnl|CDD|376519	pfam01300, Sua5_yciO_yrdC, Telomere recombination. This domain has been shown to bind preferentially to dsRNA. The domain is found in SUA5 as well as HypF and YrdC. It has also been shown to be required for telomere recombniation in yeast.	0.000116177
NC_017741.1|WP_001064288.1|988699_989611_+|polyprenyl-synthetase-family-protein	gnl|CDD|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	2.73284e-76
NC_017741.1|WP_000722482.1|989607_990411_+|5'/3'-nucleotidase-SurE	gnl|CDD|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.72244e-124
NC_017741.1|WP_001240275.1|974850_975543_-|Bax-inhibitor-1/YccA-family-protein	gnl|CDD|198414	cd10432, BI-1-like_bacterial, Bacterial BAX inhibitor (BI)-1/YccA-like proteins. This family is comprised of bacterial relatives of the mammalian members of the BAX inhibitor (BI)-1 like family of small transmembrane proteins, which have been shown to have an antiapoptotic effect either by stimulating the antiapoptotic function of Bcl-2, a well-characterized oncogene, or by inhibiting the proapoptotic effect of Bax, another member of the Bcl-2 family. In plants, BI-1 like proteins play a role in pathogen resistance. A characterized prokaryotic member, Escherichia coli YccA, has been shown to interact with ATP-dependent protease FtsH, which degrades abnormal membrane proteins as part of a quality control mechanism to keep the integrity of biological membranes.	1.37143e-51
NC_017741.1|WP_000812605.1|964552_966136_+|Hop-family-adhesin-AlpB	gnl|CDD|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	3.603e-53
NC_017741.1|WP_000010356.1|977747_983939_+|toxin-like-outer-membrane-protein	gnl|CDD|227938	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion].	1.85604e-19
NC_017741.1|WP_080024749.1|958997_960146_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|223897	COG0827, COG0827, Adenine-specific DNA methylase [DNA replication, recombination, and repair].	2.38326e-52
NC_017741.1|WP_001052413.1|986076_987222_+|tRNA-pseudouridine(13)-synthase-TruD	gnl|CDD|272903	TIGR00094, tRNA_pseudouridine_synthase_D, tRNA pseudouridine synthase, TruD family. an EGAD loading error caused one member to be called surE, but that's an adjacent gene. MJ11364 is a strong partial match from 50 to 230 aa. [Protein synthesis, tRNA and rRNA base modification].	1.99406e-142
NC_017741.1|WP_001099588.1|985498_986080_+|recombination-protein-RecR	gnl|CDD|273176	TIGR00615, Recombination_protein_RecR, recombination protein RecR. All proteins in this family for which functions are known are involved in the initiation of recombination and recombinational repair. RecF is also required. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	7.14494e-97
NC_017741.1|WP_080024713.1|968447_970136_-|TonB-dependent-receptor	gnl|CDD|366183	pfam00593, TonB_dep_Rec, TonB dependent receptor. This model now only covers the conserved part of the barrel structure.	8.13009e-24
NC_017741.1|WP_001248492.1|966672_968211_-|outer-membrane-beta-barrel-protein-HofG	gnl|CDD|334957	pfam02521, HP_OMP_2, Putative outer membrane protein. This family consists of putative outer membrane proteins from Helicobacter pylori (campylobacter pylori).	6.35112e-178
NC_017741.1|WP_000688624.1|975686_976682_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl|CDD|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	1.50142e-160
NC_017741.1|WP_080024714.1|987160_988141_+|zinc-metalloprotease-HtpX	gnl|CDD|235081	PRK02870, PRK02870, heat shock protein HtpX; Provisional.	0

Protein sequences

>NC_017741.1|WP_000688624.1|975686_976682_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MKIFINGFGRIGRCVLRAILERSDNPHLEVIGINDPANWEILAYLLEHDSAHGLLNKEARYSNGKLIIGSLEIPVFNSIKDLKGVDVIIECSGKFLEPKTLENYLLLGAKKVLLSAPFMGEYDEKQYPTLVYGVNHSLYQNQAIVSNASCTTNAIAPICAILDKAFGIKEGMLTTIHSYTSDQKLIDLAHPLDKRRSRAAASNIIPTTTKAALALHKVLPNLKNKMHGHSVRVPSLDVSMIDLSLFLEKKAFKDPINDLLIKASKGVLKGVLEIDLKERVSSDFISNPSSVIIAPDLTFTLENMVKIMGWYDNEWGYSHRLVDMAQFMYYY
>NC_017741.1|WP_001240275.1|974850_975543_-|Bax-inhibitor-1/YccA-family-protein
MALYDRANSRNAYAEDSLLQESELVGFVKTTYKFFAGSLLLATIGALLGLMNFQAVVQYKWAFFIAEIAAFFGLMFSKSKPGLNLFMLFAFTSLSGVTLVPLLGMVIAKAGLGAIWQALGMTTIVFGLMSVYALKTKNDLANMGKMLFIALIVVVVCSLINLFLGSPMFQVVIAGASAILFSLYIAYDTQNIVKGMYDSPIDAAVSLYLDFLNVFISILQIIGIFSDRDK
>NC_017741.1|WP_001126543.1|971498_974756_-|carbamoyl-phosphate-synthase-large-subunit
MPKRTDISNILLIGSGPIVIGQACEFDYSGTQSCKTLKSLGYRVILINSNPATVMTDPEFSHQTYIQPITPENIAAIIKKEKIDAILPTMGGQTALNAVMQMHQKGMLEGVELLGAKIEAIKKGEDRQAFKEAMLKIGMDLPKGRYAYSELEALEAINEIGFPAIIRASFTLAGGGSGVAYNIEEFQELAKNALDASPINEILIEESLLGWKEYEMEVIRDNKDNCIIVCCIENIDPMGVHTGDSLTIAPSLTLTDKEYQRMRDASFAILREIGVDTGGSNVQFAIHPETLRMVVIEMNPRVSRSSALASKATGFPIAKVATMLAVGFSLDEIQNDITNTPASFEPSLDYIVVKIPRFAFEKFAGVSSTLGTSMKSIGEVMAIGGNFLEALQKALCSLENNWLGFESLSKDLEMIKKEIRRPNFKRLLYIADAFRLGVCVDEVFELCQIDRWFLSQIQKLVKAEESINSSVLTDAKKLRGLKNLGFSDARIAAKIKENENLEVSPFEVELARMNLQIAPHFEEVDTCAAEFLSLTPYLYSTYAPNPFPPIENKQEKQEKKILIIGSGPNRIGQGIEFDYCCVHASFALKDLNIKSVMLNCNPETVSTDYDTSDTLYFEPIHFECVKSIIQRERVDGIIVHFGGQTPLKLAKDLAKMQAPIIGTPFKVIDVAEDREKFSLFLKELDIKQPENGMAKSVDEAYSIANVIGFPIIVRPSYVLGGQHMQILENIEELRHYLESVTHALEVSPKNPLLIDKFLEKAVELDVDAICDRKEVYIAGILQHIEEAGIHSGDSACFIPSTLSPKILDEIERVSAKIALHLGVVGLLNIQFAVHDNTLYLIEVNPRASRTVPFLSKALGVPLAKVATRVMVLKDLKEALKFYDKKNIVGYSKGVYKPKMPHFVALKEAVFPFNKLYGSDLILGPEMKSTGEVMGIARSLGLAFFKAQTACFNPIKNKGLIFVSIKDKDKEEACVLMKRLVQLGFELCATEGTHKALEKAGVESLKVLKISEGRPNVMDLMMNGEISMAINTSDHKSQDDAKLIRASVLKNHVSYFTTLSAIEVLILALEESSKEDELLALQDYLK
>NC_017741.1|WP_001229979.1|971062_971494_-|hypothetical-protein
MALVYLAQSDTTIGLLSKDSEKLNALKNRPKNQSVLIESADFTTLKSLVRAPNAFKNLIRRSAKTTFIYPNSKAVRVVRGRHGDFLKRFKTLYSTSANLTQCAYDKEIASKLADVVVSDERGLFESSSSKIFRLYKDKKVRVR
>NC_017741.1|WP_080024713.1|968447_970136_-|TonB-dependent-receptor
MAKINGYLSERDTLTLSYNMTRDNANRPLRANFTGTFLPYSCGDFNAFPNEKNPSDCLFENDASLFKTYSVNLVHNVSLNYEREGGSRFGDPKLKINGYTSIRNVQIDPLFRPNDIATIIPFTPNPELGEENECVAQGGIYDAAKQTCSITFKSLGGGSVVANKNLFIINSGFNANVIHTIDHKNDNLFEYGLNYQNLTTFDKAIPNSELVKPGDAPDACLRVTGPNDPNMNGRCQRNGASANVVGVYAQANYTLHPMVTLGAGTRYDVYTLVDKDWQLHITQGFSPSAALNVSPLENLNFRLSYAYVTRGPMPGGLVWMRQDNLRYNRNLKPEIGQNVEFNTEYSSKYFDFRAAGFVQLISNYINQFSSTLFVTNLPAQDIIYVPGYEVSGTAKYKGFSLGLSVARSWPSLKGRLIADVYELAATTGNVFILTASYTIPRTGLSITWLSRFVTDLSYCSYSPYRNGPTDIDRRPSNCPKTPGIFYVHKPGYGVSSFFVTYKPTYKKLEGLSLNAVFNNVFNQQYIDQASPVMSPDEPNQDKYARGMAEPGFNARFEISYKF
>NC_017741.1|WP_001248492.1|966672_968211_-|outer-membrane-beta-barrel-protein-HofG
MRQEKYFLTSSLSLLSFLLCPAEAFDYRFSGRVENFSKIGFNNSQINTKKGIYPTESFIDIVTLAQVKVNLLPKGTENHRLSVSLGGAIAAIPYDKTKNDINQANGKIFGSIVENFIGGYHGYFFNKYLGPAYAGTSQSASYHARPYVVDTAFLRYDYKDVFGFKAGRYEANIDFMSGSNQGWEVYYQPYKTETQRLRFWWWSSFGRGLAFNSWIYEFFATVPYLKKGGNPNNSNDFINYGWHGITTTYSYKGLDAQFFYYFSPKTYNAPGFKLVYDTNRNFENVGFRSQSMIMTTFPLYYRGWYNPETKTYSLEDSTPHGSLLGRNGVTLNIRQVFWWDNFNWSIGFYNTFGNSDAFLGSHTMPRGNNTSYIGNEISVTTRHAGMIGYDFWDNTAYDGLADAITNANTFTFYTSVGGIHKRFAWHVFGRISHANKNALGQVGRANEYSLQFNASYAFTESILLNFRITYYGARINKGYQAGYFGTPKFNNPDFSANYQDRSYMMTNLTLKF
>NC_017741.1|WP_000812605.1|964552_966136_+|Hop-family-adhesin-AlpB
MKQNLKPFKMIKENLMTQSQKVRFLAPLSLALSLSFNQVGAEEDGGFMTFGYELGQVVQQVKNPGKIKAEELAGLLNSTTTNNTNINIAGTGGNVAGTLGNLFMNQLGNLIDLYPTLNTASIHQCGSGSGSTSGTTAAATNNSPCFQGNLSLYNEMVSSIKTLSQDLKNNIFQGNNNTTSANLSNQLSNLNTASVYLAYMNSFLNANNQAGGIFQNNTSQVYGNGVTAQQIAYVLKQASITMGPSGNGGAAGAFLDAALAQHVFNSANAGNDLSAKEFTSLVQNIVNTSQNALTLANNANISNSTGYQVSYGGNIDQTHSTQLLNNTTNTLAKVSALNNELKANPWLGNFAAGNSSQVNAFNGFITKIGYKQFFGENKNVGLRYYGFFSYNGAGVGNGPTYNQVNLLTYGVGTDVLYNVFSRSFGSRSLNAGFFGGIQLAGDTYISTLKNSPQLASRPTATKFQFLFDVGLRMNFGILKKDLKSHNQHSIEIGVQIPTIYNTYYKAGGAEVKYFRPYSVYWVYGYAF
>NC_017741.1|WP_000592486.1|962983_964531_+|Hop-family-adhesin-AlpA
MIKKNRTLFLSLALCASISYAEDDGGFFTVGYQLGQVMQDVQNPGGTKRDELARELNADTTNNILNNNTGGNVAGALSNAFSQYLYSLLGAYPEKLNGNDVSANALLGGAVGSGTCAAAGTAGGNSLNTQSACTAAGYYWLPSLSDRVLSTIGSQTNYGTNTNFPNMQQQLTYLNAANVFFNAMNKALETKNGTNGASGATGSNGQTYSQDAIKYLQGQQNILNNAANLLKQDELLLEAFNSAVAANIGNKEFNSAVFTGLVQGIIDQSQKVYNELNKNPISGSAVNNAGIDNNQANAVQGRANQLSNALYNAQVTLDKINALNNQVRSMPYLPQFRAGNSRSTNILNGFYTKVGYKQFFGKKRNIGLRYYGFFSYNGASVGFRSTQNNVGLYTYGVGTDVLYNIFSRSYQNRSVDMGFFSGIQLAGETVQSTLRDDPNVKLHGKVNNTHFQFLFDFGMRMNFGKLGGKSNRHNQHTVEFGVVVPTIYNTYYKSAGTTVKYFRPYSVYWSYGYSF
>NC_017741.1|WP_000894607.1|960139_962170_+|ATP-dependent-helicase
MLETLQLNPEQLKAVKALKGYNLVIASAGTGKTSTIVGRILYLLDNGIKPEEILLLTFTNKASNEMIARVAKYSKLSSKIEAGTFHAVAYRYLKEHYPNLSLKQPKELKKLLESIVDTKNALTDDDKKPYTSQHLYALYSLYTNALKQEDFSAWLSNKNPEHTPYAAFYENILDEFENTKKKHNYIDYNDLLLLFKQAMLERPSPYKEVLCDEFQDTNPLQESILDAINPPSLFCVGDYDQSIYAFNGADISIISNFTQKYKNAQVFTLTKNYRSSKEILDLANQVIQHNERIYPKNLEVVKSGHFNKPALLNYNDNIAQCQDIAKRIVMRKNFKEVAVIFRNNASADQLEAALRSHNVPSKRKGSASFFESKEVALALDICTLIFNPKDIMAAIHVLSHISDIGSNTAKDIHEALMLLGNGDLKLALTHPNKEAKIYTKKKEITSMGLFEEIFALENSSRFNSVIDKAFHSHPVLMHPKISLNGAKMLSDFFILYTKTPTHSPSALIKHILESVFFQTFKTRLLKERSKNKDGSYNEFKKLQAQKRFNEKMDLLSSLAKNYQNLGRFLNGTLIGSSEATQGEGVNLLSVHASKGLEFKDVYIIDLMEGRFPNHKLMNTGGGIEEERRLFYVAITRAKENLWLSYAKNELRENAKPKEHKPSVFLYEAGLLKPDLK
>NC_017741.1|WP_080024749.1|958997_960146_+|class-I-SAM-dependent-methyltransferase
MYQLDIKTLGQVFTPKNIVDFMLTLKHNHGSVLEPSAGDGSFLKRLKKAVGIEIDPKICPKNALCMDFFDYPLENQFDTIIGNPPYVKHKDIAPSAKEKLNYSLFDERSNLYLFFIEKAIKHLKPKGELIFITPRDFLKSTSSVKLNELIYKEGTITHFFELGDQKVFPNAMPNCVIFRFCKGNFSRITNDCLQFVCKKGILYFLNQSYTQKLSEVFKVKVGAVSGCDKIFKNEKYGNLEFVTSITKRTNVLEKMVFVNKPNDYLLQHKDSLMQRKIKKFNEANWFEWGRMHHISPKKRIYVNTKTRQKNPFFIHQCPNYDGSILALFPYNQNLDLQKLCDKLNAINWQELGFVCDGRFLFSQRSLENALLPKDFLNEDKTC
>NC_017741.1|WP_000010356.1|977747_983939_+|toxin-like-outer-membrane-protein
MSFSGANTLNSSSPFASLKGSVSFGSGAIFNLNQTLNANQTYDILTTNATIQYGVYQSYLWDLINYKGDKAISHVEVGSNTYDVTFDINGQDETLQETFNNQSITTQFLGDDLQAKAQATYQQDLSGSQTALKNATSDNKIASSDTSYTNNQNTTIKKDAQNLENTSQQIAQDKQTLQGDLDKLQQLANATTGFNEQAFNQAQSKEQQDLQTLQNEEKTFNSEQESLDKAIANAKPASPTPSPTPTKHTAQNTPPNKVSPPTQNLPTTNVWNGVYWLQNQTYSKQGVYYIDPNLSGQSGQSGNTLSTYTANLLGRSFGVNIQNGALIIGNNTESVNDNGLIWIGHGGFGYIIGTFNAANIYLTNNFKTGEGVSGSDGGGANITFKASDNITMDGLNYNDAETVTKMIQTGASQHSYATFDATNNISVTNSSFSDMTWGKFSFSAKNISFSNASFSGFTNPGGSSVISANATNSLSFNNSRLNGGAVYNLQANSLIFNNTQAVFNVLYSRGTSNFNATTQLLGNTSFTLSSQSLLNFNGDTTLQNNANITLGNKSQATFKNSLTLDNDSNLSLDNQSVLNANGASAFNNQASLNIYNGSQATFNSLFFNGGILSLNANSKLNASSGSFSNNTTINLDDSVLSANNTSSLNANINFQGASQADFGGNTTIDTASFNFDSASSLSFNNLTANGALNFNGYAPSLTKALMSVSGQFVLGNNGDINLSDINIFDNITKSVTYNILNAQKGITGISGANGYEKILFYGMKIQNATYSDNNNIQTWSFINPLNSSQIIQESIKNGDLTIEVLNNPNSASNTIFNIAPELYNYQASKQNPTGYSYDYSDNQTGTYYLTSNIKGLFTPKGSQTPQTPGTYSPFNQPLNSLNIYNKGFSSGNLKTLLGILSQNSATLKEMIESNQLDNITNINEVLQLLDEIKITPVQKQALLETINHLTDNINQTFNNGNLVIGATQDNVTNSTSSIWFGGNGYSSPCALDSATCSSFRNTYLGQLLGSTSPYLGYINADFKAKSIYITGTLGSANAFESGGSADVTFQSANNLVLDKANIEAQATDNIFNLLGQEGIDKIFNQGNLANVLSQVAMEKIKQAGGLGNFVENALSPLSKELPTSLQNETLGQLIGQNNLDNLLNNSGVMNAIQNIISKKLSIFGNFVTPSIIENYLAKQSLKSMLDDKGFLNFIGGYIDASELSSILSVILKDITNPPTSLQKDIGVVANDLLNEFLGQDVVKKLESQGLVSNIINNIISQGGLSGVYNQGLGSVLPLSLQNALKENDLGALLSPRGLHDFWQKGYFNFLSNGYVFVNNSSFSNATGGSLNFVANKSIIFNGDNTIDFSKYQGALIFASNGVSNINITTLNATNGLSLNAGLNNVSVQKGEICVNLANCPTTKNSSSTNSSVTPTNESLSVRANNFTFLGTIASNGAIDLSQVKNNSVIGTLNLNENATLQANNLTIANAFNNASNSTANINGDFTLNQQATLSTNASGLNVMGNFNSYGDLVFNLSHSVSHAIINAQGAATIMANNNNPLIQFNTSSKETGTYTLIDSAKAIYYGYNDQITGGSSLDNYLKLYTLIDINGKRMVMTDNGLTYNGQAVSIKDGGLIVGFKDSQNQYIYTSILYNKVKIAVSNDPINNLQAPTLKQYIAQIQGVQSVDSIDQAGGTQAINWLNKIFETKGSPLFAPYYLESHSTKDLTTIAGDIANTLEVIANPDFKNDATNILQINTYTQQMSRLAKLSDTSTFASADFHERLEALKNKRFADAIPNAMDVILKYSQRNRVKNNVWATGVGGASFINGGTGTLYGINIGYDRFIKGVIVGGYAAYGYSGFHANITQSGSSNVNMGVYSRAFIKRSELTMSLNETWGYNKTFINSYDSLLSIINQSYKYDTWTTDAKINYGYDFMFKDKSVIFKPQIGLAYYYIGLSGLRGIMDDPIYNQFRANADPNKKSVLTINFALESRHYFNKNSYYFVIADVGRDLFINSMGDKMVRFIGNNTLSYRDGGRYNTFASIITGGEIRLFKTFYVNAGIGARFGLDYKDIDITGNIGMRYAF
>NC_017741.1|WP_001172978.1|983991_985089_+|Hop-family-outer-membrane-protein-HopJ/HopK
MQKTLFSLPLPFSLFLSFCIAEENGAYASVGFEYSISHAIQHNNPFLNQERIQIISNAQNKIDKLNQVKNEITSMPKTFAYINNALKNNSQLTPTEIQAEKYYLQSSFENIEKIVMLSGGAASNPQLVQALEKIQEPTTNEFEENLKNLESQFAQSQNRMLSSLSSQIAAISNSLNALDPNSYSKNISSMYGVALNVGYKHFFTKKKNQGFRYYLFYDYGYTNFGFVGNGFDGLGKMNNHLYGLGIDYLYNFIDNAQKHSSVGFYAGFALAGSSWVGSGLSMWVSETDFINNYLINYQAKMHTSFFQIPLNFGVRVNMDRHNGFEMGLKIPLAINSFYETHGKGLNTSLFFKRLVVFNVSYVYSF
>NC_017741.1|WP_001115888.1|985146_985353_-|4-oxalocrotonate-tautomerase-family-protein
MPFINIKLVPENGGPTNEQKQQLIEGVSDLMVKVLNKNKASVVVIIDEVDSNNYGLGGESVHHLRQKN
>NC_017741.1|WP_001099588.1|985498_986080_+|recombination-protein-RecR
MNTYKNSLNHFLNLVDCLEKIPNVGKKSAFKMAYHLGLENPYLALKITHALENALENLKRCASCNALSESEICEICSDESRQNSQLCMVLHPRDVFILEDLKDFLGRYYVLNSIEEVDFNALEKRLIEENIKEIIFAFPPTLANDSLMLYIEDKLQHFHLTFTKIAQGVPTGVNFENIDSVSLSRAFNSRIKA
>NC_017741.1|WP_001052413.1|986076_987222_+|tRNA-pseudouridine(13)-synthase-TruD
MNLNFMPLLHAYNHASIDFHFNSSARDFCVHEVPLYEFSNTGEHAVIQVRKSGLSTLEMLQIFSQILGVRIAELGYAGLKDKNALTTQFISLPKKYAPLLEKNTSNFQEKNLKILSLNYHHNKIKLGHLKGNRFFMRFKKMTPLNAQKTEQVLEQIAQFGMPNYFGPQRFGKFNDNHQEGLKILQNQTKFAHQKLNAFLISSYQSYLFNALLSKRLEISKIISAFSVKENLEFFKQKNLNINPNTLKALKNQAHPFKILEGDVMCHYPYGKFFDALELEKESERFLKKEVAPTGLLDGKKALYAKNLSLEIEKEFQNNLLNSHAKTLGSRRFFWVFAENVTSQYVKEKAQFELGFYLPKGSYASALLKEIKHEKGENNDEF
>NC_017741.1|WP_080024714.1|987160_988141_+|zinc-metalloprotease-HtpX
MRARCSKKSSMRKEKIMTNFEKIIVQNRLKTNAVLATYCVIFAFIGLLVDVIRINANDLGTALFKLMTFQIFPTITMVMFLVAFVIIVVCIQNFSSIMLSGDEYKLIDKSKVLSSKENQIHRLLLELLEETKLHFEPKLYIIKAPYMNAFASGWNESNSLIALTSALIERLDRDELKAVIAHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLARMILLVLQIILPFLTLLLQMYLSRTREYMADSGAAFLMHDNKPMIRALQKISNDYANNDYKGVDQNSTRSAAYLFSAEMFSTHPSIKNRIQSLSRRVI
>NC_017741.1|WP_000426951.1|988141_988684_+|GTP-cyclohydrolase-I-FolE
MENFFNQFFENIGEDKNREGLKETPKRVQELWKFLYKGYKEDPKVALKSAYFQGVCDEMIVAQNIEFYSTCEHHLLPFLGNISLGYIPKEKIVGISAIAKLIEIYSRRLQIQERLTTQIAETFDEIIEPRGVIVVCEAKHLCMSMQGVQKQNAIIKTSVLKGLFKKDPKTRAEFMQLLKS
>NC_017741.1|WP_001064288.1|988699_989611_+|polyprenyl-synthetase-family-protein
MNNPNLSFYHNECERFESFLNHHHLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCALVGQKDYSNRQTEYFKIALSIECLHTYSLIHDDLPCMDNAALRRNHPTLHAKYDETTAVLIGDALNTYSFELLSNSLLESHIIVELIKILSANGGIKGMILGQALDCYFENTPLNLEQLTFLHEHKTAKLISASLMMGFVASGIKDEELFKWLQAFGLKMGLCFQVLDDIIDVTQDEEESGKTTHLDGAKNSFVNLLGLEKASGYAQTLKTEVLDDLNLLKPAYPLLQENLNALLNTLFKGKT
>NC_017741.1|WP_000722482.1|989607_990411_+|5'/3'-nucleotidase-SurE
MKKILLTNDDGYHAKGIKALEQALEKMAEIYVIAPKHEKSACSQCITITAPLRAEKIKGKEGRHYKIDDGTPSDCVYLAINELFKHVCFDLVISGINLGSNMGEDTIYSGTVAGAIEGTIQGVPSIAISQILSHRNKNTPLSFDLAQKIIQDLVQNIFTNGYPLKGRKLLNVNVPNCSLQEYKGECITPKGYRLYKKEVHKRTDPKNESYFWLGLHPLEWQKRENEDRLSDFDAIASNHVSITPLNLDLTSYDDLKNLESWHKGMLK
>NC_017741.1|WP_000041796.1|990407_991067_+|hypothetical-protein
MSKNHRLAFLGLIVGVLFFFSACQHRLHMGYYSEVTGDYLFNYNSTIVVAYDRSDAMTSYHINVIVYELQKLGFYNVFTQAEFPLDKAKNVIYARIVRNISAVPFYQYNYQLIDQVNKPCYFLGGQFYCSQTPTDYYAINGFSEQILMSANSHFILDWYDVVLQKRVLYVDGSVSGRTCGYQMLYRDLIKSTIKRIDFNRPERYYYNLRLPLYQPCYRQ

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_017741_1	1.3|55394|19|NC_017741|CRISPRCasFinder	55394-55412	19	NC_017741.1	54418-54436	2	0.895
NC_017741_4	4.2|890583|56|NC_017741|PILER-CR	890583-890638	56	NC_017741.1	891533-891588	2	0.964

1. spacer 1.3|55394|19|NC_017741|CRISPRCasFinder matches to position: 54418-54436, mismatch: 2, identity: 0.895

aaaacaccgagctgaaaac	CRISPR spacer
aaaaagccgagctgaaaac	Protospacer
**** .*************

2. spacer 4.2|890583|56|NC_017741|PILER-CR matches to position: 891533-891588, mismatch: 2, identity: 0.964

ctaaaaaaagcgttaaggcttatttggactgcgtttcaagagctaggaatgaaaaa	CRISPR spacer
ctaaagagagcgttaaggcttatttggactgcgtttcaagagctaggaatgaaaaa	Protospacer
*****.*.************************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017741_1	1.3|55394|19|NC_017741|CRISPRCasFinder	55394-55412	19	NZ_CP041415	Escherichia coli strain STEC719 plasmid pSTEC719_4, complete sequence	25312-25330	0	1.0
NC_017741_1	1.3|55394|19|NC_017741|CRISPRCasFinder	55394-55412	19	NZ_CP041421	Escherichia coli strain STEC711 plasmid pSTEC711_5, complete sequence	26068-26086	0	1.0
NC_017741_1	1.3|55394|19|NC_017741|CRISPRCasFinder	55394-55412	19	NZ_CP041438	Escherichia coli strain STEC005 plasmid pSTEC005, complete sequence	87532-87550	0	1.0
NC_017741_1	1.3|55394|19|NC_017741|CRISPRCasFinder	55394-55412	19	NZ_CP023384	Escherichia coli strain 1223 plasmid p147, complete sequence	58372-58390	0	1.0
NC_017741_1	1.3|55394|19|NC_017741|CRISPRCasFinder	55394-55412	19	NZ_CP049202	Escherichia coli strain PapRG-04-4 plasmid pIncFIB, complete sequence	94221-94239	0	1.0
NC_017741_1	1.3|55394|19|NC_017741|CRISPRCasFinder	55394-55412	19	NZ_CP031323	Escherichia coli strain ST2350 isolate Es_ST2350_SE1_NDM_03_2018 plasmid pEsST2350_SE_2, complete sequence	71638-71656	0	1.0
NC_017741_1	1.3|55394|19|NC_017741|CRISPRCasFinder	55394-55412	19	NZ_CP023471	Salmonella enterica subsp. enterica strain BAA-1672 plasmid pSalSendai, complete sequence	78848-78866	0	1.0
NC_017741_1	1.3|55394|19|NC_017741|CRISPRCasFinder	55394-55412	19	NZ_CP050647	Escherichia coli strain PapM-36-2 plasmid pIncFIB, complete sequence	32074-32092	0	1.0
NC_017741_1	1.3|55394|19|NC_017741|CRISPRCasFinder	55394-55412	19	NZ_CP010126	Escherichia coli strain C8 plasmid A, complete genome	26196-26214	0	1.0
NC_017741_5	5.2|977626|32|NC_017741|PILER-CR,CRT	977626-977657	32	NZ_CP007648	Lactobacillus salivarius strain JCM1046 plasmid pMP1046B, complete sequence	39590-39621	8	0.75
NC_017741_5	5.3|977683|29|NC_017741|PILER-CR,CRT	977683-977711	29	NZ_CP013125	Pseudomonas mendocina S5.2 plasmid pPME5, complete sequence	6654-6682	8	0.724
NC_017741_5	5.3|977683|29|NC_017741|PILER-CR,CRT	977683-977711	29	HQ331142	Salmonella phage S16, complete genome	134111-134139	8	0.724
NC_017741_5	5.3|977683|29|NC_017741|PILER-CR,CRT	977683-977711	29	JX181825	Salmonella phage STML-198, complete genome	15162-15190	8	0.724
NC_017741_5	5.3|977683|29|NC_017741|PILER-CR,CRT	977683-977711	29	KJ000058	Salmonella phage STP4-a, complete genome	133580-133608	8	0.724
NC_017741_5	5.3|977683|29|NC_017741|PILER-CR,CRT	977683-977711	29	NC_042044	Salmonella phage Melville, complete genome	132844-132872	8	0.724
NC_017741_5	5.2|977626|32|NC_017741|PILER-CR,CRT	977626-977657	32	MF417929	Uncultured Caudovirales phage clone 2F_1, partial genome	17095-17126	10	0.688

1. spacer 1.3|55394|19|NC_017741|CRISPRCasFinder matches to NZ_CP041415 (Escherichia coli strain STEC719 plasmid pSTEC719_4, complete sequence) position: , mismatch: 0, identity: 1.0

aaaacaccgagctgaaaac	CRISPR spacer
aaaacaccgagctgaaaac	Protospacer
*******************

2. spacer 1.3|55394|19|NC_017741|CRISPRCasFinder matches to NZ_CP041421 (Escherichia coli strain STEC711 plasmid pSTEC711_5, complete sequence) position: , mismatch: 0, identity: 1.0

aaaacaccgagctgaaaac	CRISPR spacer
aaaacaccgagctgaaaac	Protospacer
*******************

3. spacer 1.3|55394|19|NC_017741|CRISPRCasFinder matches to NZ_CP041438 (Escherichia coli strain STEC005 plasmid pSTEC005, complete sequence) position: , mismatch: 0, identity: 1.0

aaaacaccgagctgaaaac	CRISPR spacer
aaaacaccgagctgaaaac	Protospacer
*******************

4. spacer 1.3|55394|19|NC_017741|CRISPRCasFinder matches to NZ_CP023384 (Escherichia coli strain 1223 plasmid p147, complete sequence) position: , mismatch: 0, identity: 1.0

aaaacaccgagctgaaaac	CRISPR spacer
aaaacaccgagctgaaaac	Protospacer
*******************

5. spacer 1.3|55394|19|NC_017741|CRISPRCasFinder matches to NZ_CP049202 (Escherichia coli strain PapRG-04-4 plasmid pIncFIB, complete sequence) position: , mismatch: 0, identity: 1.0

aaaacaccgagctgaaaac	CRISPR spacer
aaaacaccgagctgaaaac	Protospacer
*******************

6. spacer 1.3|55394|19|NC_017741|CRISPRCasFinder matches to NZ_CP031323 (Escherichia coli strain ST2350 isolate Es_ST2350_SE1_NDM_03_2018 plasmid pEsST2350_SE_2, complete sequence) position: , mismatch: 0, identity: 1.0

aaaacaccgagctgaaaac	CRISPR spacer
aaaacaccgagctgaaaac	Protospacer
*******************

7. spacer 1.3|55394|19|NC_017741|CRISPRCasFinder matches to NZ_CP023471 (Salmonella enterica subsp. enterica strain BAA-1672 plasmid pSalSendai, complete sequence) position: , mismatch: 0, identity: 1.0

aaaacaccgagctgaaaac	CRISPR spacer
aaaacaccgagctgaaaac	Protospacer
*******************

8. spacer 1.3|55394|19|NC_017741|CRISPRCasFinder matches to NZ_CP050647 (Escherichia coli strain PapM-36-2 plasmid pIncFIB, complete sequence) position: , mismatch: 0, identity: 1.0

aaaacaccgagctgaaaac	CRISPR spacer
aaaacaccgagctgaaaac	Protospacer
*******************

9. spacer 1.3|55394|19|NC_017741|CRISPRCasFinder matches to NZ_CP010126 (Escherichia coli strain C8 plasmid A, complete genome) position: , mismatch: 0, identity: 1.0

aaaacaccgagctgaaaac	CRISPR spacer
aaaacaccgagctgaaaac	Protospacer
*******************

10. spacer 5.2|977626|32|NC_017741|PILER-CR,CRT matches to NZ_CP007648 (Lactobacillus salivarius strain JCM1046 plasmid pMP1046B, complete sequence) position: , mismatch: 8, identity: 0.75

atagccttcaatccacttttaataacagcaat	CRISPR spacer
gcgtcattcaatccacttttaatataagcaac	Protospacer
... * ******************  *****.

11. spacer 5.3|977683|29|NC_017741|PILER-CR,CRT matches to NZ_CP013125 (Pseudomonas mendocina S5.2 plasmid pPME5, complete sequence) position: , mismatch: 8, identity: 0.724

ccgacaacgccagcttcaataacgacacc	CRISPR spacer
gcgacaacgccggcttcaataaggctcgt	Protospacer
 **********.********** * .  .

12. spacer 5.3|977683|29|NC_017741|PILER-CR,CRT matches to HQ331142 (Salmonella phage S16, complete genome) position: , mismatch: 8, identity: 0.724

ccgacaacgccagcttcaataacgacacc	CRISPR spacer
agtgaatcgccagcttcaataactacaca	Protospacer
   . * **************** **** 

13. spacer 5.3|977683|29|NC_017741|PILER-CR,CRT matches to JX181825 (Salmonella phage STML-198, complete genome) position: , mismatch: 8, identity: 0.724

ccgacaacgccagcttcaataacgacacc	CRISPR spacer
agtgaatcgccagcttcaataactacaca	Protospacer
   . * **************** **** 

14. spacer 5.3|977683|29|NC_017741|PILER-CR,CRT matches to KJ000058 (Salmonella phage STP4-a, complete genome) position: , mismatch: 8, identity: 0.724

ccgacaacgccagcttcaataacgacacc	CRISPR spacer
agtgaatcgccagcttcaataactacaca	Protospacer
   . * **************** **** 

15. spacer 5.3|977683|29|NC_017741|PILER-CR,CRT matches to NC_042044 (Salmonella phage Melville, complete genome) position: , mismatch: 8, identity: 0.724

ccgacaacgccagcttcaataacgacacc	CRISPR spacer
agtgaatcgccagcttcaataactacaca	Protospacer
   . * **************** **** 

16. spacer 5.2|977626|32|NC_017741|PILER-CR,CRT matches to MF417929 (Uncultured Caudovirales phage clone 2F_1, partial genome) position: , mismatch: 10, identity: 0.688

atagccttcaatccacttttaataacagcaat	CRISPR spacer
atagccttcaatccaccattaatggacactgc	Protospacer
****************. *****..  .* ..

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	194794 : 204617	10	Helicobacter_phage(80.0%)	NA	NA
DBSCAN-SWA_2	1513292 : 1524218	9	Bacillus_phage(33.33%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_017741|194794:204617|DBSCAN-SWA
TTTAATTTAACATCAATAAAGCAAGCTCATTCTGCACCGCTGGGCTTAATTGTAAAAAGCGTTGCAAAATCCGTTCATCGCTTTCTCCGATTCTGTAAAATCCTAGAATGTTTTTAATTTTGGTTTCTACTTCATAATATTCTTTTATGCTTTTGTTCTTATCACTAAAAGCCGCTCTTGCGTAAGTTCTTCCTGTGTGGTTAAAATAAGGCTGTATTCCTAAAAAATTGTCTTTTGTACCTAATTCTTTAATCGTTAGTCGTTCGTTGCCTATAGCGTTAATTTCGTTATTTAGGTTCTGTCTTTCTTGTTCTTTCTCTCGTTTAGCATTTTGTTGGTTCTGTCTTTCTTGTTCTTTCTCTCGTTTAGCATTTTGTTGGTTCTGTCTTTCTTGTTCTATAGGATTTTTTGCGTGTTCTTTTTGATTTATAGCGTTCTTTAGCGCGTTAATATAGTTTTGCTTGGCTTTGATGCTTTCTTTAAATTTTAGGGCGTTTTCTTGCTCTTTTTGTAGGTCTTGCGTTAAAGCGTTCAAGTCTTTGTCGTTTAAGCGCTCTTGCTCTTGTTTAATGGTTTTTTCTAATTCTTCAATCCTTTTTAAATTTTTCTTGCTAGTTTTAGCCGTTAAGATCTTAAGCCTTAAGCCTTTGGCGTATTGGGAGATCTGTTTGAAAAATAAGGCGCTTTGTGTATTCTCGCTTTCTGGATGGTAATTCAAAACCAAATCATAAAACTTCAAGGCTTTCACTTGTTCTATAGAGCCTAAAGCGTTGTAGCTATCATTACCGGGTAAAAACTTTTGATAGCTGTTATCTAAAACCTGGTTTAGTGCATTGACTTTAAACTGGTTATTGATGCCGTCCATGTTGTTAGGAGCGTTTAGAGCGTTGTAGGTTTCTTTGCCGGGATTATGATATTCGTAGATAAAGCCTTTAGGTAGTATCGCATAAGGATCAGTTAAAAAAAAGTTTAAAAAAGCTGCGTGTTCTTGGCTTGCTTGTAAGGCGCGTTGCTGTTTGGCTTCTTTATTAGAAGAGTTGTCGGTCAAAAAATTAAATTGTTTCTTCCATTTGGATTTTTTTTTAAGCCGTTTGAGTTCTTCTTTAAGTTTTTCTAATTTTTTCAAGCTTTCTTCAATTTGATTTTTATTACTCGTTTCTAATTCTAAAGCGTTTAATTTTTCTTGTTCTTGTTTGATTGCATTCTTTAGCGCGTTAATTTCGTTATTCAAGTTCGCTATTTCTTGGTTTAGGTTACTTATCGCTTGGTTTTGCTTGTCTATTTCTTGGTTTATGTGGTGTATTTCATTATTCAGGCTGTTAATGGCGTTTTCTTTATCCATTATTTCTTGTGTGAGTTGGTTGATGCGGTTTTGATGGTTTATAAGGCGTCCAAAAGCGTTTTTTAGCCGTTCATTAGAATAATAGTTTTTCTGCGCTAAGAATTTTCTACTCACGGCGTAATAGCCGTTAGGATCATCATAGTATCCTACGATTTGATCGTTTTCATTGCTTAATTGCCTAGGAAATCCGCTAATACCACCAAAATGCGCGTTATTTAAAGCATTACCTAAAGACTGGATAAAACCGCTTAAAATAGCGTTAGAGCCTTGAGAGCTAGATCCAGGACTTACGCTTATATCAATCCAACTCATGCATTAATCCTTTTGAATTTCTTTAATTTTAGCGTTTATCGCTTCAGCTAAAGCGTAATCCTTGCAATCTAGCGCAACCGCTAAAGAATTTTTTAAGCCTTTGGTTTTGAGCCACACTAATGAGCTTTTTTGATAGCTTTCAGGAATAGTTTTAAATTTTTTCAAAAAATCTAAACCTCTAAAATCACTGCACACAATCCTTTTAAAAAATGTAGGATATTTAACATCGCTTGGCGTTAAAAAGCGCCTTGCAATGTACCTAAACTCTTCGCTTTCAAGCATTGTTGCATAAACTCTCGCTTCTAGTAGATCTAATTTACCGGGTAAATTTTTCTGCTTAACGGGTTTAACGCTTTTTTGCGCTAAAAATGAATTTAATATTTTGAGTAAATCCGCTTGCATGAAAGGTTCAAAAGCTTCAAGGATCTTTAAAATATTTCTGTAGTTTAAATCCTTTTGTGGCGTGGTCAGTTCTGCTCGTAACAAATAGGAGCAATAGAATTTAAAGCCGTTAATTTTGGCTAGGTTAGGGCGTCTGTTAAGTTTTTGATAATCGCTTAAATCCTTAACACTTGAGTCTTTGATCTTAATAACGCTCATGTTGGTTACATGGTTTTTCAAACACAAATCAAGCGCTCTAATGGTGGCTTCTGTTCCGGCGTTATCGTTATCAAAACTAAAACACAACTCCACATTAAGCTTATTTAAAAACGCTAAATGTTCTTTAGTGAATGCGGTACCGCTTGTACAAATTGCGTTTTTATAATAAAAATGTTCGTACGCTAACACATCAAAAAAACCTTCACATATAATAACCTGCTTCTTTTCTTTGATAGATTCAAGCGCTCGGTGGTAGTTATACAAGAAAAATGTTTTATTATAGAGGCTTGTTTCTCTGCCGTTAAGGTATTTAGGAGCGTTGTTAGCTTTTAGAAGTCTTGGTATACACAAACGCGCGCTAAAGCTTCTAATTTGGCCTTTGCTATCCTTTAACGGAATTGTAATGCGGTAGTTGCAAAAACTTCTTAATTCTTTGTCTTCGTTTTTGTTAGAGAAAAGACCGCATGCGATCAAATCATCAGCATTAAAGCGTTCTTTCAAAACTTCTAAATCACCATGCAAACAATAACCTAAATCATAAGCTTCTATCATTTCTAAACTAATCGCGCGCGTTTGCGTGAGGTAGTTCAACACTTTCGGCTCGTTTTTTAGCCGTTCTTTAAAAAGATTGTTAGCGTAAGCTAAAATTTCTTTTAAATGGTTGTTGCGTTCAATTTTAGCATCGGTTTCGTATTCTAAATGATAATTATAGATTTTAGCCACTTCTTCAACGGCTTCAAGAAAACTTAATTTTTTGTATTCTTGCAAAAACTTCAAGGCATCACCGCTCACACCACATCCAAAACAATGATAAATATTTTTTTCAGGACTTACGATAAAACTTGCACTTCTTTCATCATGAAAAGGACAGCACGCTTTGAAATTCGCTCCAACTTTGTGAAAATCAATATAACTCTCCAAAACTTCCATGATTTGAATACGATCTTTTAGTGGCGCTAAATTAGTGATTTTCATATTAAGCCTCCGTATTCTTCATGTTCGTCATGTTGGAATTGTTGTCCAGATCCGTTATAATCCACTTCAAAAAAACGATAATCAACATTTTTAACATACCTATAACCGCTTAAACCTGTTTGCTTGTTCTTTAGTATAACAATTCTTCGGTGCTTAGCTCGCTCGTTAAAGTCTTTAAGGTGTGGTAACTCGTTCCTTTTTATCCGTTCTATGCGAATCATCAAATGCGCTTCATGACCACCTTTGCGTGATCCTGTTGGCGTGTAGCTGTCGTTTTTAGAATTTTGCACAATGAGAATAATCAACACCTGCAAGCTCCTAGCGGTTTCACCTAAAGCGCTAAATTTAGAAGTTTCTATTTCTTCAATAGTCCTTCCTACGATTGGCGCTTGGATCTTCATTTGGCTGTCTATTAAAAAAACCTTATGTCCCTCTTTGGATAGCGATCGTATTTGAGAAATGAGATCGTTTAGTTCGCAACTTTGATCGTCTATAAAATAGTTATCCGCTTTAATATTAAAATTTTTATTCCTTAAGGTTTCAATGTGCTTCCTAACGCTAAATTCAAAACCAAAATAAGTTACCTTGTGTTGTTGTTGCGCGTTCATTAAAAACTGCACACCTAAAAGCGTTTTACCGGCTTCTGGATCGCCGCTAAGTAAAACTATTTGTCCTAATTCGATTCCTCCTTCTGTGATGATGTCTAAATAGTTAATACCAGTTTCTATCTTTTCAATAGGAGGCTTATTTTTAAAATACTCCTCCCATTCCCAAAAATACTTACCACTTCTAACGATTCCTAGGTTGATGTATTTATTCAAAAATTCATAATCAAAAACTTCACTTTTGCGCGTGGCTTCTTTAAGTTTGTTGGCGAGATGTTCTTGCATTTGAAAACACAAATACGTTTTAAAATCGCTTTTCAAATTCAAATAATCCGGGTAGCTATCCGCTTCTAAAATGCGTTTAAACTCTTCGCTTTGAAATTCCTTTTCTGCGATCCTAAGCTTGATCGTTTCAAGCCTTGGTACTTGGTTTCTTTGGTTCATTTCAATTAAAACCTTGATGAGTTTTTGATTAAATGGATTAAAACTTTTAACGCTGATGTCTTTTAAAAAATCCTCTATGTGTTGCGGATAGTCTAAAAAACTTTTCATTATCAAATTTTCCATGCCGTTTCCTTTATCGTTTCTTTTGGTTTTTTTCTTCTAAAATTTCTAAAAAGCTGTCAAATTCCTTTAAAGTCAAATGCACTAAAAGATTTTCATTTTTGAATTGCTTAAGACCTTTCAAAATAGCTAAACGCACGATTTGCGCTAATTTGTAATTGTTTTTTCTTTTCAGCCTTTTTAATTCTTTCAAGTTGCTGTCTCTTAAGCTTATTTTTTTTCGTTTGGTTAATAAGAGTTCTTTTATAAGCGCGGTTCGATCGTTCCCATGCCTTCTCATTGCTTTGTCCTTTCTGCGTTTCTAAGTAAAAAATAATCAAGCGCTCTGTTATCTGGCTTCGAGATCGATTCTCTATGATTTTAAGCAATTCTAAAATCTCTAAAAGCCCGTTTTCTATTAGAATACTATTCGTCCATACCTTTGGCTTGAAATTCTTGTTAGCGTGCTTGTAATTCCACGATCGCATGATTTCACCTACCAAAAATAAAGCCGTTATAGCAATCGTTGTATTCAAACTGATCCATGACTTCTTCGCCTTTGGCTTTGCTTTGGCAACTTGGCTTTTCAAAATGCATGACCTCATAGATTTCATTATAGTTTCGGCGTATGGATTGGTTGATACAAGCCACTAAATCGTATCCTTGCGCTTTCAAGGCTTCGCATTGGTGCAAAAGCGCTTTTTTAGTGCTATAGCTTAATTTGTGCTTCTCGCTGCGATAATTCAAAAATTCTTCAAAAGCTAACCTTTCGTATTGGTTCAAGTGTTTCGTGTCTAAATTTCCTAAAATAGAGCTAAAAAAAGCGCTAAAACGATCAAATAAACTAAAATTAGAAATATTTGAGCTTTTAAGAGAAGAATCTTTGACGGAATCTTTTAGATCTCGATCGTTTGAGAAGACTTGTTGTTTTTCATCAAATTTTTTCGTTGAAAAATTTTCACTTGAGCGTATATTTTCATGTTTATTTTTATTTTTTCTTTTTAATGTAAACGATGGAAAATAAGTACTCATGGATTGAGCTTCGGTATCATCGGCGTTAGAGGCTTGTTTTTGCGGGTTTATCCAGACGGAAATATTTTCCTTGTGGATAGCGTCTTTTTTGGCTGATTTTTGAGCTTGTTTTTTAGAAAAATTTCCCATGATAAATCTAAAAAATTTAGAAAATGTGCCGTCTTTTTTTCGCTCTCTTTCAAATTCAATATAACCTAAATCTTTTAATTCGTTTAGGTACTTGTAAATCGTTTTTGTGTTCCTATTGAATCGTTTGGCTATGTCTTCAATGCAGAGCTTAAAAGTGGTTGCGTGCTTTTTGATATAAGCATAGATCGCTATCGCTATGTCAGAGACTCGTTCGTCCTCGCAAATTTCATTAGAGATTTGCGTATAACCAAATTTCATTGGTTGTTTTAGGATGTAGTTCATTGTTGATCCTTTTTTTTGGTTTTAACGCTTTTTAAAGCTTTTAAATAGGTGCATAGATCTTTCCCAAAATCGCTTAAACAACAAACCTTGTAATAGTTGTTTTTCTTTTCTTTTTCTTTCTTTTTATTGATAATCCACTGAATGCATAAGCCTTTAGCTTCAAGCTTTTTAAAAATATTAAGCGTGTAGTAGTAATCAATTCTGAGATCTTTTGAAATCTTGTCGGCTGTTTTAGGCAAATACGCTTTCTTGTTGAGCGCTATTAAAACTTCTAAATCGATCGGTTTTAGTTTTTCTTGTGTCATGTTCAAACCGCTTTTTTTTGGAGTAAGATTGAATAGCTCGTTACGCGCTTATTTCTCACATTGCAAACGCTGGATCTAATCGTATGCGTTTTTTGGAGTTTTTCTAATTTTTGGATGAAATCAAAAAAACTTAAATCCGTATTGCTTTCTTTGATCGTTTGGTAAGCTAGGTATTGAAAAATTTCCATGTTGGTTTCCTTTTTACTCATAATAATTCCTTTGTGAATTTCGCTCGTTCTTTGTCTTGTTTAGGTATGTAGTGGCTGTAAGTGCTGTAAGTCGTGTTCAAATCTTTATGACCTAGAGTTCTGCTGATCCACATTGGTTCTTCGCCTTGGCTTAGCATCAAGCTTGCAAAAGTGTGGCGTGTGGTGTAAAGCTTTCTGTCTTTCAAGTTCAAGGCTTTTAAAAGTTTTTTGAAATGCCTTTGAAAGATACTTGATCGCTTTGGCATGTCTATGAAAACGAATTTTTTAGTATCCGGTTCGCTTTCTTTAAGCTCTTTTAGGATTTTCTCCACTGGCTCTAATAGATCAACTTCTCTAATGCTTGGCTTGTTTTTAGGACTTGTGATTTCTCCTAGTTCGTTTAAGGACTTGTTAATAGTGATCGTTTTTTCTTTAAAGTCAATGTCTTTCCATTGTAATGCTAACTGCTCGCCGGTTCGTGCGCCTGTAAAAAACGCTACTACTAAAAACGCTTTTAAGCGTAATGTTGGAGCGTTCTCTATGAGCGTTTTAACCTCTTCTAAACTAAAAGGCTCGATCGCTTTGGCTGCTAGCGCGTTTTTAAGTGTGATCGTATAATAAGGATTTTGAGGTAAAAACCGCTCTCTCTCACAAAACGCTAAAAAGCTTTTTAGATTAGCGTTAAAGTTGTGGATCGTGTTCTTTCTGTAGAGTGTTAGCGTGGCTTGGTGGTATTGTGCGATCTTTTCTTTAGTGATCTTTTTGAGCTTGTCGCTTTCTTTTAAGCCCATCACGCTAAAAATGCTATTGAAAACATTTTCTAAAGAATTAAGGCTCGTTTGTTTTAGTCCTATTTTTAACGATAGAAAACGATTTAACGCTTGAAGTATGGGTGATCTTTGACTGAATCCTATGCGTTTGTTTTTCGGCGTTTTTAACGCGCTTATTGGCGTTTTTTATCGCTTCTAAACGATTAACAAAAGCTAAGATCTCTTTAAGCTTTTTGTCTTTGAAATATTCTAAGGCTGTGTCGGTATCCATTTTTAAGCAATCCGTGGCTTTTCTTAAGCTCACTCTAAAACGCTTATTCTTGTTATCGTGATAGTTGAGATATAGAGTCGCTTCGCCCTTGTAATCTCGTGTGTATAGTGTGAAGGTGTTCATAATAGACTCCTTAAAGCGTAAGCTGTAGCTAGAATCAAGCTAAACGCTATTATTAACGACCATTCAAAACGATCCGCCATTTTTTTTTCTAAAGGCCTGTTAAGTTTTTTATTAGGCTTTAGCATTGTTGTCTCCTTTTTGGTTGGCTTCTTTGGTTTTAGTCCTTGCGTTAGCGCTTTCTTGTATTGGCTCTCTAATCGTGGTTTTTTGTCTCTCGCTAAAGGTTTTTTTTGTAGGCTTTAGAACGCAATTTCCTTGTGCGCGCCTTTTAGGCTCTTGAGCCGCGCGTTTAGGTGTAAGTTCGCTCACATTGGCGTTTTGGTTAGTTTTAAGCGCTTGATGCGCTTGAATGCTTTGAGTGATTTCCTTAAGCTGGTTAAAGCTTGTTTCTGTCTCTCTTTTTTGTCTCATATTTTGATGCTCCTTTCGTGTTTTAACGCCCTTCTATAGGCGTTTATAAGTTTAAAATGCGTTAAGCTTTTAAAAATATTTGTTTTTTTGTGAGACAAAAAGTTTAACCCCCGACATGGGTTTTTGAGTGTCAAAAATTACTTATTTTTTTCAAATAAGCTCCCTATCTTGTGGCTCTTAAAAAAGATTTTTGTTTTTGTATTTTTTAGGTTTTTAGTGTGTGGTTTTGTTGAAGTTGTGAAATAAGCTATAATAAGCCCATTTTGAATACGAATGATTATTTTAATAAGGACAATCAATGAAAGATAGTTTTCTTTTCACTTCTGAATCAGTAACCGAGGGGCATCCTGATAAAATGGCTGATCAAATCAGCGATGCGGTTTTAGATTACATTATTGAGCGCGATCAAAAAGCCAAAGTCGCATGCGAGACTTTAGTTTCTAACGGGTTTTGCATGATCACTGGCGAGTTAAAAACTTCTGTTTATGCCCCTATGCAAGAGATTGCAAGAGAAGTGGTTAAAAAGATTGGTTATACAGACGCTCTTTATGGCTTTGATTATAGAAGCGCGGCGGTTTTAAATGGCATTGGCGAGCAAAGCCCTGATATTAATCAAGGCGTGGATAGAGAAGATGGCGAGATTGGGGCGGGGGATCAAGGGCTTATGTTTGGTTATGCGTGCAAGGAGACTGAAACGCTCATGCCCTTACCCATTCATTTAGCGCACCAGCTCACTTTCGCTCTGGCTCAAAAAAGAAAAGACAACACTCTGCCTTTTTTAAGGCCTGATGGCAAGTCTCAAGTGAGCGTGCGTTATGAAAACAACAAGCCTGTAAGCATTGATACGATTGTCGTTTCCACCCAACATTCCCCAGAAGTTTCGCAAAAACATTTAAAAGAAGCCGTGATTGAAGAGATCGTGTATAAGGTTTTACCCAAAGAATATTTGCATGACAATATCAAGTTTTTTGTCAATCCTACAGGAAAATTCGTTATTGGTGGGCCGCAAGGCGATGCGGGCTTGACGGGCAGAAAAATCATCGTGGATACTTATGGGGGGAGTTGCCCGCATGGGGGGGGAGCGTTTAGCGGGAAAGACCCTAGTAAAGTGGATAGGAGCGCGGCTTATGCGGCCCGCTATGTGGCTAAAAATTTGGTAGCGAGTGGGGTTTGCGATAAAGCGACCGTGCAGCTTGCTTATGCGATTGGGGTGATAGAGCCGGTGTCTGTTTATGTGAATACGCATAACACGAGCAAGCATTCAAGTGCGGAGTTGGAAAAATGCGTGAGATCGGTTTTCAAACTCACACCAAAAGGCATTATTGAAAGCTTGGATCTGTTAAGGCCCATTTATTCGCTCACTTCAGCTTATGGGCATTTTGGGCGAGAATTAGAGGAATTCACTTGGGAAAAAACCAACAAAACCGAAGAGATTCAAGCGTTCTTTAAGCGTTAAAAAAATGTTTTAAGGGTAATATTTTAAAAAATTTTTGTATAATCAACAATTCACAAGGAGTTTAAATTGAAACAAAGAACGCTGTCTATTATTAAGCCGGATGCACTTAAGAAAAAAGTGGTAGGCAAAATCATTGATCGCTTTGAGAGTAACGGCTTGGAAGTCATTGCGATGAAACGCTTGCATTTGAGCGTTAAAGACGCTGAAAATTTTTATGCGATCCACAAAGAGAGACCCTTTTTTAAAGATTTAATAGAATTTATGGTCAGTGGTCCGGTGGTGGTTATGGTTTTAGAGGGCAAAGATGCGGTGGCTAAAAACAGAGATCTTATGGGAGCGACTGATCCCAAACTCGCCCAAAAAGGCACTATCAGAGCGGATTTTGCTGAAAGCATTGACGCTAATGCGGTGCATGGGAGCGATAGCTTGGAAAACGCGCACAATGAAATCGCTTTCTTTTTTGCCGCTAGAGATCTTTAA

Protein sequences of DBSCAN-SWA_1

>NC_017741|194794:204617|204203_204617_+|WP_000813725.1|DBSCAN-SWA
MKQRTLSIIKPDALKKKVVGKIIDRFESNGLEVIAMKRLHLSVKDAENFYAIHKERPFFKDLIEFMVSGPVVVMVLEGKDAVAKNRDLMGATDPKLAQKGTIRADFAESIDANAVHGSDSLENAHNEIAFFFAARDL
>NC_017741|194794:204617|196450_198022_-|WP_000705261.1|DBSCAN-SWA
MKITNLAPLKDRIQIMEVLESYIDFHKVGANFKACCPFHDERSASFIVSPEKNIYHCFGCGVSGDALKFLQEYKKLSFLEAVEEVAKIYNYHLEYETDAKIERNNHLKEILAYANNLFKERLKNEPKVLNYLTQTRAISLEMIEAYDLGYCLHGDLEVLKERFNADDLIACGLFSNKNEDKELRSFCNYRITIPLKDSKGQIRSFSARLCIPRLLKANNAPKYLNGRETSLYNKTFFLYNYHRALESIKEKKQVIICEGFFDVLAYEHFYYKNAICTSGTAFTKEHLAFLNKLNVELCFSFDNDNAGTEATIRALDLCLKNHVTNMSVIKIKDSSVKDLSDYQKLNRRPNLAKINGFKFYCSYLLRAELTTPQKDLNYRNILKILEAFEPFMQADLLKILNSFLAQKSVKPVKQKNLPGKLDLLEARVYATMLESEEFRYIARRFLTPSDVKYPTFFKRIVCSDFRGLDFLKKFKTIPESYQKSSLVWLKTKGLKNSLAVALDCKDYALAEAINAKIKEIQKD
>NC_017741|194794:204617|194794_196447_-|WP_000118378.1|DBSCAN-SWA
MSWIDISVSPGSSSQGSNAILSGFIQSLGNALNNAHFGGISGFPRQLSNENDQIVGYYDDPNGYYAVSRKFLAQKNYYSNERLKNAFGRLINHQNRINQLTQEIMDKENAINSLNNEIHHINQEIDKQNQAISNLNQEIANLNNEINALKNAIKQEQEKLNALELETSNKNQIEESLKKLEKLKEELKRLKKKSKWKKQFNFLTDNSSNKEAKQQRALQASQEHAAFLNFFLTDPYAILPKGFIYEYHNPGKETYNALNAPNNMDGINNQFKVNALNQVLDNSYQKFLPGNDSYNALGSIEQVKALKFYDLVLNYHPESENTQSALFFKQISQYAKGLRLKILTAKTSKKNLKRIEELEKTIKQEQERLNDKDLNALTQDLQKEQENALKFKESIKAKQNYINALKNAINQKEHAKNPIEQERQNQQNAKREKEQERQNQQNAKREKEQERQNLNNEINAIGNERLTIKELGTKDNFLGIQPYFNHTGRTYARAAFSDKNKSIKEYYEVETKIKNILGFYRIGESDERILQRFLQLSPAVQNELALLMLN
>NC_017741|194794:204617|202979_204137_+|WP_000655143.1|DBSCAN-SWA
MKDSFLFTSESVTEGHPDKMADQISDAVLDYIIERDQKAKVACETLVSNGFCMITGELKTSVYAPMQEIAREVVKKIGYTDALYGFDYRSAAVLNGIGEQSPDINQGVDREDGEIGAGDQGLMFGYACKETETLMPLPIHLAHQLTFALAQKRKDNTLPFLRPDGKSQVSVRYENNKPVSIDTIVVSTQHSPEVSQKHLKEAVIEEIVYKVLPKEYLHDNIKFFVNPTGKFVIGGPQGDAGLTGRKIIVDTYGGSCPHGGGAFSGKDPSKVDRSAAYAARYVAKNLVASGVCDKATVQLAYAIGVIEPVSVYVNTHNTSKHSSAELEKCVRSVFKLTPKGIIESLDLLRPIYSLTSAYGHFGRELEEFTWEKTNKTEEIQAFFKR
>NC_017741|194794:204617|200609_200918_-|WP_000191219.1|DBSCAN-SWA
MTQEKLKPIDLEVLIALNKKAYLPKTADKISKDLRIDYYYTLNIFKKLEAKGLCIQWIINKKKEKEKKNNYYKVCCLSDFGKDLCTYLKALKSVKTKKKDQQ
>NC_017741|194794:204617|199204_199471_-|WP_001252548.1|DBSCAN-SWA
MRRHGNDRTALIKELLLTKRKKISLRDSNLKELKRLKRKNNYKLAQIVRLAILKGLKQFKNENLLVHLTLKEFDSFLEILEEKNQKKR
>NC_017741|194794:204617|198018_199194_-|WP_000429246.1|DBSCAN-SWA
MENLIMKSFLDYPQHIEDFLKDISVKSFNPFNQKLIKVLIEMNQRNQVPRLETIKLRIAEKEFQSEEFKRILEADSYPDYLNLKSDFKTYLCFQMQEHLANKLKEATRKSEVFDYEFLNKYINLGIVRSGKYFWEWEEYFKNKPPIEKIETGINYLDIITEGGIELGQIVLLSGDPEAGKTLLGVQFLMNAQQQHKVTYFGFEFSVRKHIETLRNKNFNIKADNYFIDDQSCELNDLISQIRSLSKEGHKVFLIDSQMKIQAPIVGRTIEEIETSKFSALGETARSLQVLIILIVQNSKNDSYTPTGSRKGGHEAHLMIRIERIKRNELPHLKDFNERAKHRRIVILKNKQTGLSGYRYVKNVDYRFFEVDYNGSGQQFQHDEHEEYGGLI
>NC_017741|194794:204617|200920_201127_-|WP_000037340.1|DBSCAN-SWA
MSKKETNMEIFQYLAYQTIKESNTDLSFFDFIQKLEKLQKTHTIRSSVCNVRNKRVTSYSILLQKKAV
>NC_017741|194794:204617|202381_202681_-|WP_001249252.1|DBSCAN-SWA
MRQKRETETSFNQLKEITQSIQAHQALKTNQNANVSELTPKRAAQEPKRRAQGNCVLKPTKKTFSERQKTTIREPIQESANARTKTKEANQKGDNNAKA
>NC_017741|194794:204617|199662_200613_-|WP_001106767.1|DBSCAN-SWA
MNYILKQPMKFGYTQISNEICEDERVSDIAIAIYAYIKKHATTFKLCIEDIAKRFNRNTKTIYKYLNELKDLGYIEFERERKKDGTFSKFFRFIMGNFSKKQAQKSAKKDAIHKENISVWINPQKQASNADDTEAQSMSTYFPSFTLKRKNKNKHENIRSSENFSTKKFDEKQQVFSNDRDLKDSVKDSSLKSSNISNFSLFDRFSAFFSSILGNLDTKHLNQYERLAFEEFLNYRSEKHKLSYSTKKALLHQCEALKAQGYDLVACINQSIRRNYNEIYEVMHFEKPSCQSKAKGEEVMDQFEYNDCYNGFIFGR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000118378.1|194794_196447_-	hypothetical protein	A0A1S5RGC7	Helicobacter_phage	9.9e-112	74.3
WP_000705261.1|196450_198022_-	DNA primase	A0A1S5RFI1	Helicobacter_phage	3.9e-259	84.1
WP_000429246.1|198018_199194_-	helicase DnaB	A0A1S5RHD0	Helicobacter_phage	1.5e-199	88.0
WP_001252548.1|199204_199471_-	hypothetical protein	I6P597	Helicobacter_phage	2.3e-31	83.0
WP_001106767.1|199662_200613_-	helix-turn-helix domain-containing protein	I6P4A6	Helicobacter_phage	1.5e-133	78.9
WP_000191219.1|200609_200918_-	hypothetical protein	A0A1S5RHA0	Helicobacter_phage	1.2e-31	69.3
WP_000037340.1|200920_201127_-	hypothetical protein	A0A1S5REX2	Helicobacter_phage	4.0e-23	83.6
WP_001249252.1|202381_202681_-	hypothetical protein	A0A1S5RFL3	Helicobacter_phage	3.0e-11	56.5
WP_000655143.1|202979_204137_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	9.0e-120	57.1
WP_000813725.1|204203_204617_+	nucleoside-diphosphate kinase	A0A0G2Y5H2	Acanthamoeba_polyphaga_mimivirus	9.3e-19	39.7

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_017741|1513292:1524218|DBSCAN-SWA
ACTACCCTTTTAATTCATTCCAACGCTTAGCCACAAACGCGCTCGTTTCTAGCGGCACCCTCAAAGGATAAACTTCATCATTGAGGATGCGTTGGATTTCTTGCTGCAACTTTAGGGCGTTTTTTTCTTCAATCTCAAAAATCAATTCGTCATGCACTTGCAAAAGCAGCCTCACCGAAGGGTTATTTTTGAAACGCTCGCTCACTTTAAGCATGCCCAATTTCAACAAATCGCTCGCGCTCCCTTGGAAAATCGCATTCACGCCCTCTCGCAAATAATTGCCCTTGATGTGATCATTTGCACCGGTAAAATCAAACACCCGATAACGCCCAAGCAAAGTAAAGGCCTTAGAAGTTTTTAAAATCTCTTCTTTCATGCGGTTTAAGTAATCTTTGATGCTAGGGAATCGTTTGAAATACGCTTCTATGTAGCTTTTAGCCTCATTTAAAGGGATGTTTAAAGTTTCGCTCAATTTCTTACTCCCCATGCCATACACCAGCCCAAAATTAATGCTTTTAGCGATGGATCGTTTTTCTTTGGCCAAATCTTCTCCAAACAACGCCTTAGAAGTTTCTAAATGGATGTCTCGCCCCTTTAAAAACGCATCCATTAAATCCTTATCCTGACTAAAATGGGCTAACAAGCGCAATTCAATCTGCGAATAATCCACCCCTAGCAAGCAATATTCTTTAGAGCTGGCGATAAAACCTTTACGAATGAGTAAGCCTTTAGGCGATCGCACCGGGATATTTTGCAAATTAGGCGAATGCGAGCTTAAACGCCCGGTAGCTGTGCCGGTTTGGATGAAAGTGGTATGGATTTTATCGTCTTTGTCTTTTAAGCGCAATAAGGGGGTGGTATAAGTGTTAAAAAGCTTATTCAATTCTCTGTATTCTAAAATCAAAGCGATGCTTGGGTGCTTGTCTAGGATTTTTAACAAGCTTTTTTCATCAGTAGAACGGCTTTTATTTTGAGGAAGCTCTAATTTTTCATACAAAATCTCGCTGAGTTGTTTGGGGGAGTTGAGGTTAAAATCCACGCCGATTAGATCCAAAATTTGGCGCTCTAAAACATGCAATTCATTCTTAAACTCCTGCTCTAAGCGCTTGAAATAAGGTGCATCAATCTTAAAGCCTTGAAATTCCATGCCCATTAAAACTTTCATTAACGGCGTTTCAACTCCTCTAGCCAAAGCAAGCAAACCCTCTTCTAGCCCCCCTTTTTCAAAATACTCGCACAAACGCTTTAAAGCGTTTAATTCCATATCCAATTGCTCTAATTTTTCCACCTTACTTTTTGTCTTAAAATCTTTGATTGTTTCATGCGGGATCAATTCTTCTTTTAAATATTCCTTTAAAACTTCATCAAACCCCACTTTTTCCGGATTTTTTAAAAACGCTAAAATTTGAGTGTCTTGGATGCGAATGTTTTCTAAAGAAACCTGGTATTTGGCTTTTAAAAAGCTTAATAAGGGTTTTAAATCATGCCCAATGATTTGCACATGCTGTAACATTTTAAAAAAAGCGTTTTGCAAAAACTCTAAAGAAAAGGGCGAAAATAACGCCTCTTCTAAAGGTAAAAAATAGCCTTGATCTTCATATAAAAACGCTAGGGCCAGAACTTTTTTTTCTTTATCTAACACCAAACGCACAAAAATCCTTGCGTTAGAATTTTTTAATTTTTCTAAAAACGCGCTCAAAGGCTCGGTGTTTTCTAAAACGATCAAGCGTGATTTTTTAGGGGCGTTGTCTGATGCGGGCGTGTTTTCTAATAGAGGCGTGTTGTCTAAAATTAAAGGCGTAGGGGAATTTTCTAAATCCCTTAAAGTAGAAATAAAACCATATTCTTTCAATTCATCTTTGATTTTCAATAAAGGGTTTTCGCTAGGAAAAGCGCAACTTAAAAAATCAAATTCTTTAATGCATCCTCTTTGTAAAGTGGCTAATTCTTTGCTTAAAAACGCGCTCTCTTTGTCTTGTATAAGGGCTTGATACATTTTAGGGCTGAGTAAATTTTTCGCCAAGTCTAAATTTTCATAGATTTTTTCCAAACTCCCTAAGCGCTGTAACAATTCCTTAGCGTTCTTGCTCCCAATGCCTTTAACCCCCTTGTAATTATCGCTGCTATCCCCCACAATGCCCTGATAATCCGTGAATTGACTCGGCAAAATCCCGTATTTTTCCACGCAATCTTTCGCCAAAAATTCCGTTTTGCCATCAAAAAGCGCGATTTTATCGCTCAAAAGCTGGTTAAAATCCTTATCTTTAGAATAAATGCGGGTTTTATAAGGGCTTAGCGTGGCCAGGCTTGCGATGACATCATCAGCTTCAAACCCGCTCACCTCCACGCAAGTAAAACCCATTTTTTGCAACCATTCTAATGCAATAGGGATTTGTAAAAGCATCTCTTTAGGGGCGTCTTTACGATTTTGTTTGTATTCGCCTAATCTTTCAGCCCTTTTAGTTTTAGTCTGGCTTTCTAGAGCGAACACGATAAAAGGCATGTTTTTTTTATCTTTATAAAATTTTTTAACCATGCCCACAAGCCCCGTTAAAAGCCCCGTAGGAAAGCCCTTATCATTGGTTAAAGGCTTGTTTTTAGCGCTCATGTAATAGCTTCTAAACAAATACGCAAAAGTATCAATTAACGCTAAAGTCCCCTCTTTAATGACTGGCTCTTCCATGCATCAACCCTCTTCAATCAAGCAAATTTTAAGTTTATTGTAACACAAGCTTGACCTCATCTGTTTCAAAACAACGAGTCTTTTTGGGTTGGCGTTTCTTGGCTGATGGCTTCTTTTGTGGCCTGTATTTTAGCGCTGCTGTATTGAACCACGCCTTGAATGGTTTGTTTCATTAGGGCGTTGATAAAGGTGCGCATGAAATGAAAATCAATATCCTTAAGGGTTTGAGTGTTAGCGGTGGGTTTTAGGGGTAGAGAAAATTTAAATTCCGCAATGCTTTCTGTTGTAGAGCCTAGCCCCCAAGTTAAGGGTTTTAAAATAAATTGTAAAATCGCGCTTATAAAATATAAAATTTTAGGACTCTTGAAAGCAAATTTTGGTTTTAAAATTTTAACCCTATTGCCTGTAAAATAAGGTTGTTTTTGATAGAACACGGTGAAAGTGTCTTGCGCGAACGAAAGGGTATTTTTTTCATTAGCAAATGTAGAGTCATCTATAATAAAGCCTTTTATACCATTGTTGGTTGCAGCGCGCACGACATAAGGGTAGCTGTTTTCTATTTGCGTGTCATGGATTTTTATCGTGTTGGCATGATAAATTTTCTTACTTGACAACACTTCAAACAAATCCCCTAATTTGAAGCTTTGCCATGTTAAGCCGCATGGGGTATTACCCCCCCCAGAATTTTTGCCATTGAAAAGGTTAAGGGCGTTTTCTTCATCGTTAGAAAGGGTGGTGTTTGATAGCCCTGTAGCTTTTAAATAAGCCTCAAGTTCGGCGAGCCGACACTGCTCAAGTTCGGCTATGAATTTTTCCATGAAATGAAAATCAATACCATCAAGGGTTTGAGTGTTAGCGCTGGGTTTTAGGGGTAGAATGACTTTATCGTTTTTAATTTTTGCCCATGAACACATGTTTTCATAGCCGAATTTTTTAGGGTAATCAAAAAATAGCGTGGATAAAAACAAGCCGATTTTATGGTTGATTTCAAATTTAGGTTTGAGAGAAAATACCCTAGCGTGTGTTACCATTTTATAAGGAAAACTGCGATAAAACGCGCAACCAAACATGTCAATAGTAATGCTATGGCTTTCAAAAACTTTTGCTTTTATATCGCTTTGCCCTAAAACGCCATTATTGCTAAGCCCTGCGGTGATGACAAATTCGCCCTTATGATTGATGTGGCGTTTTTGAATGTCAAAATCGCCGTTACTCGCTTCAAACAAATCCCCCAATTTGAACTCGCCCCACTTAATAGCGTTGAGTTGGCTACTAAGGGGCCAATCACTTTGGGGGCGTTTGGCTTTTTAAAATCAAGCCCACTTCATAAGAAAGGTAATCGGCTATCGTTCTTTTAAAATCCTCTAATTCGGGTTTAGTCTCATTCTTTTGATGGGCTTCAAAATTAAAGTCTTTAGCATGCTTACTTTCATGCGGCTTAGCGATAAAATCTTCAATATAGATGGTTTTTAAATCGCCCCACAGCTCTTTAGAAACTTTAGCGTTTAAGCCGGCTTTGTAAATTTTAATGATTTCTTCGTAGCGTTTGGTGGGGTTAGAGGTTTCATTTAAGCCTCTTTTGGTGCGCTTGAAGCCGTCGTTTCTAAAGTCTATGAATTTAACGGGCTTTTCATAATCGTGTGGCTCATGAGCTTTAAAAATATAAACGCTTGTTTGCACCCCGGCTTGCGGCATGAATAAATCGGTGGGCATTTTAACGCTCGCTAAAAGCGAATGTTTTTTTAAAATTTCAACATTGGATTTTAAAGCTTGCCCACTCCCTGCGCTATCTTGGATAATGATCGCTCCTAAAGCGCCTTTTTGCATATATTCTAATCCAAACTTGATAAAAGGCATGCCGTTTTCTTCGTAGCTAAAAGGAGGGTTTAATAAAAGGATATTGGGTTTAAAATCTTCATAAATCTTTTTATTGGTTTCAAAAGTGTTGCCTTTGATGATCAAACTTGATCCATCGCCTCTTAAAATCATGTTAGTGGTGGCTAGCGAAAACATTTCAGCGTTAAGCTCCACGCCTAAAAGTTGCGTGGTTTTTGCGTTTTTTATTTTTTCGTTAGCTTTAGTGGTGTTTTTACCATAGGTTTTTTCAATGTCTTCAATCATTAACACCATAGAAGAAATTAAAAAGCCCGCGCTCCCTGTGGCTAAATCCATCACAAAAGACTTCGCATTAACCCCTAAAAGTTCGCTCATCATTTTAGTTACATAAGGTGGGGTTAAAACAATGCCTAATTCCTTACCATCCCCTAAAGCGTATTTTAAAAATTCGCTATAAAGTTCGCCCATGATGTCTAAATGACCGGTATTGTCGCTTTCATTAATGGGCTTATGGACAAATTCATAAAGAAAGGTAAAAATTTGCTTAGTGATACTTGAATCTTTTTCTAAAAGCATGCTTATGGCTTTATCAAGGCTCGTTTCTTTATCGCGCTGCGGGTCTTTACTGATTTCTTTAAAACTGGCGAGCATTAGATCTCGTTTTTCTTCGCTCAAGTTTTTGGTTTTCAAAAATTCGCTAATTTGGTTAAACACTAAAACACCATCACGGCTAGTATCGGTCAATTCGCCTTTCAAATCGCTTGGTTTTAAGCCCTCTTTTTTGCCTTTAATTTCTTGCATGGATAAAAGCATGCCGCTCACATATAGCGCGCGCTGAGGCGCTGTGATGTTGTGGTTATGCATAAGGCGGTTGAGTTTTTTAGCGGTTTCGTTTAGATCGGCTTTGGTTTTGATTAAGATAGAATGCTTTTCTGCTTCAGTGAGCGTGCATTCTTCATAAAAAGCGTTAAACGATTCTTGATTTTCTAAAAAATGCAGGTTTTTAGCGTTAGTGAGTTTGTGCGAATTGATCCCGCTTGCAAAAACATAATACACTTCTATAAAAAGGTTCTCTTCATCATCGCCGGCTATGCCTATGGCGATACATTCTTTATATTTTTCTTTGTTTTTTAGGATATTTTGAGCGTAGTGTAAAGCCCCATTCACGGCGTATTTTGAAATGGAATGGTCATCGTTTTGCAGCGTGGAGTTTTTGAGCTTTTTTAAATTTTTAGCGTAGAGTTTGTTTTCTATGATTATAGGGATAACGCTCTCTTTATTTTTAGGGTGCGTGTATTTTTCTAAACTAAAATCTGGCTCGCCATAAGAAGTTTTGTCTTTAGTTTTACTCGCATTCAAAAGGGCGCTTTTAAGGCTAGAACTCATTTGGCTTTTAACATTAAAATCCTTATTTTTCATAAGCCCTAATTTTGCCAATTCTTTTTTAACATAATCATCAACATCATCTTCTAACTGAAAAGCTTGCATGGTTTTATCCTTTTAAAAATTAAAATTATAACTCATTCATCCGCGCTGCAAAGCGCGATCGCAAAGTGCGCTTTGATGTTTAGGGTTTTAAGGTATTTTAGGGCTTCTTTTAGGGTGGTGCCGGTGGTGATAATATCATCTAATAAAAAATAATCTAAATTTTTATCGCCTTTGAAGGTGAAATTCCGTGGGTTATTGGCGCGAAATTCTAAGCTTTTCCCAGCATACGAAACAGCATTAATAGCCCTTAAACGCCCGTAAGTGGCTTTTAAATTGCCTTGACAAAAGCCTTTTAAAAGCGCGGCTGAATGCGAGTAAAAGGATTTGATTTTATCATCAATGGCGATGCCATAAAGGGGGGTAGTCAAGCCTTTTTCTTGCAGGATTTTCACAAATTCCGCGCCGGCTTTTAGAGAAAGCAAGGGCAAAATGCGAGAGCCAATCAGCGCGTATTTGCTTTTAATGAGCTCTTCTATTTCGCTATAAGCGTAAAAACTATACACGCTCACGCCCTCTAAAACCCTTACCTTTAAGCTTAAGGGCAAATCGTTCAAGCAATTTGGGCAAAGGGGCTTAAAAGAAAGCTTCAAACAAGTTAAACAACGCATTCAATAAAGGCTACGATCTGGCGGTGCAGATCCCAAACGCTTTTTTGAGCGTCTAATTCCAAAACTTCGCACCCGAATTTTTCTTTTAACGCATGAGCGTGAGTTTTGAGCTTTTGCTGGATTGTGAGTAATTTTTCTGTGCCTTGGTTTTCTATTTTGTCTAAACTTTTAAGGCTTAAGCGCTGTTTTAAGCCCTCTTTGTCTATGAGTAACAGAATGATTTTTTCAGGCAAGACGCTTTGAGTGGCAAGCAGGTTTAATTCTAGGCTTGAAAATTGGCTATAAGCCATGCCAGAAATCAAACTCCTATCGCTAATGATGAGCTTTTTTTCTTTCAGTGCCGGTTTTATCACGCTTTCTATATGCTCAGCCCTATCGCTTAAGAATAAAAACGCTCTAGCCAATTCGCTGATGCTTTCATTTAAAGCGATATGCCTTAAATGTTCGCCCATTCTCGTCCCCCCTGGCTCTTTGGTAACAAGGGCGTTTTTAAACCTGTCTTTTAATAATCCTACTTGAGTGCTTTTGCCCACGCCATCAACGCCTTCTAACACCACATACATTTTAAACCTTTGAAATAAAAGGGTGGATTTCTTTAGGCACTAAATGGCTCGCATCGCCCTTATGCGCGATAATGGATCGCACGATAGAAGAGCTTATGAAAGCGTTTTGTAAAGTGGGCATGAAATACAAGGTTTCTAATTCGTGGTTTAAGGATTTGTTCGCATAGCCCATTTGCAATTCGTATTCAAAATCGCTCACCACCCTTAAACCCCTAACTAGCACCTTGCAATGATACTCTTTAGCCAGATTGGCTAATAGCCCTTCAAACGCCACGCATTCTACATTTTTAAAACCTTTAGTGGCCAGTTGCATCATTTCTAAGCGCTCTTTCAAACTAAACATGGGGTTTTTAGCGCAAGAATACGCCACAGCGACAATGAGCTTTTCAAACAATTCGCTGGATCGATGGATAATGTCTATATGCCCGTTAGTGACCGGATCAAAAGTGCCCGGGTAAATGCCAATTTTTTGCATCAGTTCATTCCCCATCGTGGGTATAAGTCATTTTCTATCCCTAAGCTGTCAAACCACTTCCCCACTAAAAAATCTTGCATCGCTTCTAAAGTCTTGCTCTGGGTGTAATAAGTCATCATCGGCGGTGCAATGATTGCATTAGAGCGGGCGAGTTTGAGCAAATTTTCCAGCATGATAGCGCTTAGGGGCATTTCTCTAGGGGCAATGAGTAAGGGGCGCTTTTCTTTAAGCATCACAGACGCGCTCCTAGAGATCAAATCCCCCCCAAAGCCATGCGCGATTTTAGCCACCATGTCCATGCTCGCTGGAATGATCGCCATTTTATGGATACCATAACTCCCTGAGGCGATGCTCGCATGGATGTCTTGCTCGTTAAAAAAAGTAGCGCTAGGCCGTAAATCTTTCATGGCGTTTTTAAGGTTAATGTTAGACTCTTCTAACGCCACGACATGCGCGTTTTTAGACGCCACGACAAAAACTTCAATTTCTTTGGGTAATTTTTCTAAAAACCGCAAGGCTAGGGGTATCCCGCTCGCCCCACTGATACCTAAAACTAATTTCATGAATGTCCTTTATAAGATTTGCGCTTTAGAGCTGCTCAACACTTTTGCTTTCAGTATTTTATTGCTTTCTAAATTTTTCGCTTGAATGATTTGATTGAGCGCGCCATTTTCTAGGGCTTTTAGGCTTATTTCTATGCTGATTTGCCCTTCTTCATACACCCCAGTGATAATGTCGTTTTTACGCACGATGATTAAGGCTTGGGTTTTATCCGCGCTTAAAAGCGTGTTAGGGGGGATAAAATTTTTCGCGCTCACTTTATTAATCGCGCCCTCTAATAAGGGGTTAGAAAGCGCGCCAAACAAAACGCGCTCTTTTTGGGTGTTGTTAGCGGTGATGTTTTCATCTTTTTTAATCGCTCCTACGCTTTTAAAAGCCTGCATGCTGCCTATCACGCTATAACGCACCGGTAGGCGTAAATTAGGCTCATTTTCTAACCTTAAAAACACGACCCCATCTTTTTTAAGCTTGTTAGAAGCGTTTAATTCATAGCTTAAAATTGAAGCGTTAGAAAAGCGCTCTGGGATTTCTAAGTTAATGGTTTCAATTTCTAATTTTAAGTCTTTGTATTCTTTAAGGTAAGCTTTTTTAATCTCTGTTTTAAGCGCGTTTGAATCTAGGGCGAATAGCGCGTTTAAACAAATAAAAAAAAAGATTAAAATTTTCAAAACCCGTTATCCACTTTTTCTACAAATTTTACTGAGATTTTATCATAGACATTCCCTCCGCAATTGATTTTCAAGCACAAACCGCTCAAGCCTTTTTCTACGCCTAAAACCCTACCGGTGCCAAAAATCTTATGCCTGATCAAATCCCCCACTTTAATGGGCGCGTCTTTTTTGTGATCCTGTTTAGGGGGGTTGTCTTGCTTGAGCAACTTGGCTTCTTCTAAAAACACAGAGGGCGAACAAGAAATTTTCCTCCCAAAATACGAACGCTCTTGAACATAAGAGAGCTGCAATCCTTCTTTAGCCCTAGTGATCGCTACGTAAGCCAAGCGCCTTTCTTCTTCTAAATCGCTTTCTTGATTGAACCCCCTATGCGGGAAAAACCCTTCTTCTAACCCGATCACAAACACATGCTTAAACTCTAACCCCTTACTCATATGCACGCTCATGCAACTCACTTTTTGCGCGTTTTCTGTATTATGGGTATCTAGAACGCTTTCATTCAAAAAATCCAATAAAGAATGCGTGGGGTTAGTTTTAAAATGCTCTTTCACTAAGGCTAAAAGCTCTTTAACAAAGCCCTCTCTTTCTTCGTAATTGTCTTCTTTTTCATAGCTTTTTAAAAGGTTGGTTTCTTCTAAAAACCGAGCGCAAAACTCCTCTACTGAAATTTCAAAAGCCTCCCTCAAACGCCCTATCATAGCGATAAATTTATTCAAAGCGTGTTCGTTTTTAGGGTTTAATTTGCCTTTAAACACCCCAAGTTTTAGCGCTTCTTCTAAATTCAAACCCTCATCATCTAAAAGAGAAAAAATCCATTCTTGGGTGATCTTGCCAAGGCCTCTTGAGGGCTTGTTTAAAACGCGCCTGATAAAAAAGCGATCGTCTTTTTTAGCCACTAAATGCATGAACGCCAAAGCGTCTTTAACCTCTGCTCTTTCATAGAAACTTACCGCTCCAATAAGCCTATAGGGGATATTCAAAGCGTTCAAGCTCTCTTCAATGCTGCGGCTAAGCCCGTTTAAGCGATACAGTATAGCGATATTTTCTAAATTTTCACCCTTCTTTAAAAGGGCTTTGATTTGATAAGCCACATCTAAGCTCTCTTCTTTTTGCGTCAAATATTCCTTACAAACCACGCTTTTATGCGATCCTTTGAAACTTTGAAGCGTTTTTTTGTGGCGGTGTTGGTTATGGCTAATAAGGGAGTTAGCGCACGCTAAAATTTCAGCGCTGGAGCGGTAGTTGGTTTCCAATTTCACCACCTTAGCCCCTTTAAAATGCTTGGAAAAATTTAAAATATTAGAAATATCAGCCCCCCTAAAACCATAAATGCTCTGATCGTCATCGCCCACCACGCACAAATTATGGTGCGTGAAACTCAATTTTTTTAAAAATTCTAATTGCAAGGCGTTCGTGTCTTGATACTCATCTACCATAATGTAATGGTAGCGCTCGCTAGTTTCTTTGGCGATGGTTTCATTATCTTGCAAAATCTTAAGGCTTAAAAAAAGCAAGTCGTCAAAATCCACTAAATTGTCTTTTTTAAGCGCGTTTTGGTAAAGCTCATACGCTTTATGACATTCGCTATCTTGCATGCTTAAATCAATCATGCCGTTTTTGATCTGAGAAATACTGGCTCTAAAGCTTGAAATTTTAAGCTGTTTGCACAGCGTTTTTACTTCATCGCTATCTAACACCGAAAAATCGCACGCTCTTTTTAAAAGGCCCATGTGTTGCCTTAAAAACAGCAAACCAAAACGATGGAAAGTGCAAAGCAAGGGGGGGATAAGGGTTTGGTTTTCCAACAATTTCAAAGCCCTTTCTTGCATTTCTTTACTCGCTTTATTGGTGAAAGTGAGCGTTAAAGTGTTCTCGCTAGGCACGCCACAAGCGCCAATCAAATACGCTAAACGGCTCGTTAAAGTCTTAGTCTTACCGCTCCCAGCTCCCGCTAAAATCAGCAAAGGCCCTTGAATGTGGCTTGCGGCGATTTTTTGCGCTTCGTTTAAATTGTCTAAAATACTTTTTTCAAAATCCATTAT

Protein sequences of DBSCAN-SWA_2

>NC_017741|1513292:1524218|1513292_1515974_-|WP_000392400.1|DBSCAN-SWA
MEEPVIKEGTLALIDTFAYLFRSYYMSAKNKPLTNDKGFPTGLLTGLVGMVKKFYKDKKNMPFIVFALESQTKTKRAERLGEYKQNRKDAPKEMLLQIPIALEWLQKMGFTCVEVSGFEADDVIASLATLSPYKTRIYSKDKDFNQLLSDKIALFDGKTEFLAKDCVEKYGILPSQFTDYQGIVGDSSDNYKGVKGIGSKNAKELLQRLGSLEKIYENLDLAKNLLSPKMYQALIQDKESAFLSKELATLQRGCIKEFDFLSCAFPSENPLLKIKDELKEYGFISTLRDLENSPTPLILDNTPLLENTPASDNAPKKSRLIVLENTEPLSAFLEKLKNSNARIFVRLVLDKEKKVLALAFLYEDQGYFLPLEEALFSPFSLEFLQNAFFKMLQHVQIIGHDLKPLLSFLKAKYQVSLENIRIQDTQILAFLKNPEKVGFDEVLKEYLKEELIPHETIKDFKTKSKVEKLEQLDMELNALKRLCEYFEKGGLEEGLLALARGVETPLMKVLMGMEFQGFKIDAPYFKRLEQEFKNELHVLERQILDLIGVDFNLNSPKQLSEILYEKLELPQNKSRSTDEKSLLKILDKHPSIALILEYRELNKLFNTYTTPLLRLKDKDDKIHTTFIQTGTATGRLSSHSPNLQNIPVRSPKGLLIRKGFIASSKEYCLLGVDYSQIELRLLAHFSQDKDLMDAFLKGRDIHLETSKALFGEDLAKEKRSIAKSINFGLVYGMGSKKLSETLNIPLNEAKSYIEAYFKRFPSIKDYLNRMKEEILKTSKAFTLLGRYRVFDFTGANDHIKGNYLREGVNAIFQGSASDLLKLGMLKVSERFKNNPSVRLLLQVHDELIFEIEEKNALKLQQEIQRILNDEVYPLRVPLETSAFVAKRWNELKG
>NC_017741|1513292:1524218|1519330_1519906_-|WP_001203560.1|DBSCAN-SWA
MRCLTCLKLSFKPLCPNCLNDLPLSLKVRVLEGVSVYSFYAYSEIEELIKSKYALIGSRILPLLSLKAGAEFVKILQEKGLTTPLYGIAIDDKIKSFYSHSAALLKGFCQGNLKATYGRLRAINAVSYAGKSLEFRANNPRNFTFKGDKNLDYFLLDDIITTGTTLKEALKYLKTLNIKAHFAIALCSADE
>NC_017741|1513292:1524218|1520943_1521507_-|WP_000780116.1|DBSCAN-SWA
MKLVLGISGASGIPLALRFLEKLPKEIEVFVVASKNAHVVALEESNINLKNAMKDLRPSATFFNEQDIHASIASGSYGIHKMAIIPASMDMVAKIAHGFGGDLISRSASVMLKEKRPLLIAPREMPLSAIMLENLLKLARSNAIIAPPMMTYYTQSKTLEAMQDFLVGKWFDSLGIENDLYPRWGMN
>NC_017741|1513292:1524218|1522169_1524218_-|WP_080024733.1|DBSCAN-SWA
MMDFEKSILDNLNEAQKIAASHIQGPLLILAGAGSGKTKTLTSRLAYLIGACGVPSENTLTLTFTNKASKEMQERALKLLENQTLIPPLLCTFHRFGLLFLRQHMGLLKRACDFSVLDSDEVKTLCKQLKISSFRASISQIKNGMIDLSMQDSECHKAYELYQNALKKDNLVDFDDLLFLSLKILQDNETIAKETSERYHYIMVDEYQDTNALQLEFLKKLSFTHHNLCVVGDDDQSIYGFRGADISNILNFSKHFKGAKVVKLETNYRSSAEILACANSLISHNQHRHKKTLQSFKGSHKSVVCKEYLTQKEESLDVAYQIKALLKKGENLENIAILYRLNGLSRSIEESLNALNIPYRLIGAVSFYERAEVKDALAFMHLVAKKDDRFFIRRVLNKPSRGLGKITQEWIFSLLDDEGLNLEEALKLGVFKGKLNPKNEHALNKFIAMIGRLREAFEISVEEFCARFLEETNLLKSYEKEDNYEEREGFVKELLALVKEHFKTNPTHSLLDFLNESVLDTHNTENAQKVSCMSVHMSKGLEFKHVFVIGLEEGFFPHRGFNQESDLEEERRLAYVAITRAKEGLQLSYVQERSYFGRKISCSPSVFLEEAKLLKQDNPPKQDHKKDAPIKVGDLIRHKIFGTGRVLGVEKGLSGLCLKINCGGNVYDKISVKFVEKVDNGF
>NC_017741|1513292:1524218|1517258_1519298_-|WP_001147671.1|DBSCAN-SWA
MQAFQLEDDVDDYVKKELAKLGLMKNKDFNVKSQMSSSLKSALLNASKTKDKTSYGEPDFSLEKYTHPKNKESVIPIIIENKLYAKNLKKLKNSTLQNDDHSISKYAVNGALHYAQNILKNKEKYKECIAIGIAGDDEENLFIEVYYVFASGINSHKLTNAKNLHFLENQESFNAFYEECTLTEAEKHSILIKTKADLNETAKKLNRLMHNHNITAPQRALYVSGMLLSMQEIKGKKEGLKPSDLKGELTDTSRDGVLVFNQISEFLKTKNLSEEKRDLMLASFKEISKDPQRDKETSLDKAISMLLEKDSSITKQIFTFLYEFVHKPINESDNTGHLDIMGELYSEFLKYALGDGKELGIVLTPPYVTKMMSELLGVNAKSFVMDLATGSAGFLISSMVLMIEDIEKTYGKNTTKANEKIKNAKTTQLLGVELNAEMFSLATTNMILRGDGSSLIIKGNTFETNKKIYEDFKPNILLLNPPFSYEENGMPFIKFGLEYMQKGALGAIIIQDSAGSGQALKSNVEILKKHSLLASVKMPTDLFMPQAGVQTSVYIFKAHEPHDYEKPVKFIDFRNDGFKRTKRGLNETSNPTKRYEEIIKIYKAGLNAKVSKELWGDLKTIYIEDFIAKPHESKHAKDFNFEAHQKNETKPELEDFKRTIADYLSYEVGLILKSQTPPK
>NC_017741|1513292:1524218|1519893_1520469_-|WP_000289772.1|DBSCAN-SWA
MYVVLEGVDGVGKSTQVGLLKDRFKNALVTKEPGGTRMGEHLRHIALNESISELARAFLFLSDRAEHIESVIKPALKEKKLIISDRSLISGMAYSQFSSLELNLLATQSVLPEKIILLLIDKEGLKQRLSLKSLDKIENQGTEKLLTIQQKLKTHAHALKEKFGCEVLELDAQKSVWDLHRQIVAFIECVV
>NC_017741|1513292:1524218|1520470_1520944_-|WP_014662293.1|DBSCAN-SWA
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAYSCAKNPMFSLKERLEMMQLATKGFKNVECVAFEGLLANLAKEYHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIHPFISKV
>NC_017741|1513292:1524218|1516039_1517230_-|WP_041199807.1|DBSCAN-SWA
MKWGEFKLGDLFEASNGDFDIQKRHINHKGEFVITAGLSNNGVLGQSDIKAKVFESHSITIDMFGCAFYRSFPYKMVTHARVFSLKPKFEINHKIGLFLSTLFFDYPKKFGYENMCSWAKIKNDKVILPLKPSANTQTLDGIDFHFMEKFIAELEQCRLAELEAYLKATGLSNTTLSNDEENALNLFNGKNSGGGNTPCGLTWQSFKLGDLFEVLSSKKIYHANTIKIHDTQIENSYPYVVRAATNNGIKGFIIDDSTFANEKNTLSFAQDTFTVFYQKQPYFTGNRVKILKPKFAFKSPKILYFISAILQFILKPLTWGLGSTTESIAEFKFSLPLKPTANTQTLKDIDFHFMRTFINALMKQTIQGVVQYSSAKIQATKEAISQETPTQKDSLF
>NC_017741|1513292:1524218|1521516_1522173_-|WP_000697511.1|DBSCAN-SWA
MKILIFFFICLNALFALDSNALKTEIKKAYLKEYKDLKLEIETINLEIPERFSNASILSYELNASNKLKKDGVVFLRLENEPNLRLPVRYSVIGSMQAFKSVGAIKKDENITANNTQKERVLFGALSNPLLEGAINKVSAKNFIPPNTLLSADKTQALIIVRKNDIITGVYEEGQISIEISLKALENGALNQIIQAKNLESNKILKAKVLSSSKAQIL

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000392400.1|1513292_1515974_-	DNA polymerase I	A0A142F1Q9	Bacillus_phage	5.3e-46	28.2
WP_041199807.1|1516039_1517230_-	restriction endonuclease	A0A1W6JNN3	Staphylococcus_phage	1.1e-06	21.0
WP_001147671.1|1517258_1519298_-	N-6 DNA methylase	A0A2H4JBT5	uncultured_Caudovirales_phage	4.2e-213	58.7
WP_001203560.1|1519330_1519906_-	ComF family protein	NA	NA	NA	NA
WP_000289772.1|1519893_1520469_-	dTMP kinase	R4TMK1	Halovirus	6.4e-10	40.9
WP_014662293.1|1520470_1520944_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	4.8e-27	44.4
WP_000780116.1|1520943_1521507_-	UbiX family flavin prenyltransferase	NA	NA	NA	NA
WP_000697511.1|1521516_1522173_-	flagellar basal body P-ring formation protein FlgA	NA	NA	NA	NA
WP_080024733.1|1522169_1524218_-	DNA helicase UvrD	A7KV33	Bacillus_phage	6.3e-92	34.6