CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_018147	Zymomonas mobilis subsp. mobilis ATCC 29191 plasmid pZZ6.02, complete sequence	0 crisprs	NA	0	0	0	0
NC_018145	Zymomonas mobilis subsp. mobilis ATCC 29191, complete sequence	5 crisprs	cas6f,cas7f,cas5f,cas8f,cas3f,cas1,cas3,DEDDh,csa3	0	5	4	0
NC_018148	Zymomonas mobilis subsp. mobilis ATCC 29191 plasmid pZZ6.03, complete sequence	0 crisprs	NA	0	0	0	0
NC_018146	Zymomonas mobilis subsp. mobilis ATCC 29191 plasmid pZZ6.01, complete sequence	0 crisprs	NA	0	0	0	0

1. NC_018145

CRISPR-Cas detection and classification

Crispr_ID: NC_018145_1

• CRISPR_ID: NC_018145_1
• CRISPR_location: 125613-125820
• CRISPR_type: Orphan
• Repeat_type: I-F
• Spacer_info: 3 spacers

Consensus repeat of NC_018145_1

Consensus_repeat	Method
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC	CRISPRCasFinder
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC	CRT
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC	PILER-CR

spacers of NC_018145_1

>1.1|125642|30|NC_018145|CRISPRCasFinder,CRT
TTGTCGCGTTCGGCATTTCCAGTTTGTCAG
>1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR
ACACGCTTGATCTTCTTCTGTGGCGCGATGC
>1.3|125761|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR
AATCTGTTCAACACTATCAGCTTGCAATTTA

CRISPR arrays and Neighbor proteins around NC_018145_1

CRISPR arrays

The CRISPR arrays of NC_018145_1

>merge|NC_018145|1|125613-125820|CRISPRCasFinder,CRT,PILER-CR
GCCCTTAAACTACCTCTGCGGCAGTGAACTTGTCGCGTTCGGCATTTCCAGTTTGTCAGTTTTCTAAGCTGCCTGTGCGGCAGTGAACACACGCTTGATCTTCTTCTGTGGCGCGATGCTTTTCTAAGCTGCCTGTGCGGCAGTGAACAATCTGTTCAACACTATCAGCTTGCAATTTATTTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NC_018145|1|1|125613-125820|CRISPRCasFinder
GCCCTTAAACTACCTCTGCGGCAGTGAAC	TTGTCGCGTTCGGCATTTCCAGTTTGTCAG
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC	ACACGCTTGATCTTCTTCTGTGGCGCGATGC
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC	AATCTGTTCAACACTATCAGCTTGCAATTTA
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NC_018145|1|1|125613-125820|CRT
GCCCTTAAACTACCTCTGCGGCAGTGAAC	TTGTCGCGTTCGGCATTTCCAGTTTGTCAG
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC	ACACGCTTGATCTTCTTCTGTGGCGCGATGC
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC	AATCTGTTCAACACTATCAGCTTGCAATTTA
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NC_018145|1|1|125672-125820|PILER-CR
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC	ACACGCTTGATCTTCTTCTGTGGCGCGATGC
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC	AATCTGTTCAACACTATCAGCTTGCAATTTA
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018145.1|WP_014848230.1|131526_133050_+|glucose-6-phosphate-isomerase	unknown	unknown	gnl|CDD|366041
NC_018145.1|WP_014848223.1|123532_123796_+|twin-arginine-translocase-TatA/TatE-family-subunit	unknown	unknown	gnl|CDD|234822
NC_018145.1|WP_011241032.1|130769_131195_-|hypothetical-protein	unknown	unknown	gnl|CDD|227505
NC_018145.1|WP_011241044.1|119062_119692_-|50S-ribosomal-protein-L9	unknown	unknown	gnl|CDD|234659
NC_018145.1|WP_011241045.1|117990_118986_+|dipeptide-epimerase	unknown	unknown	gnl|CDD|239435
NC_018145.1|WP_011241042.1|119951_120326_-|30S-ribosomal-protein-S6	unknown	unknown	gnl|CDD|179034
NC_018145.1|WP_014848229.1|129121_130642_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223587
NC_018145.1|WP_014848221.1|120825_121761_+|ACP-S-malonyltransferase	unknown	unknown	gnl|CDD|223408
NC_018145.1|WP_014848225.1|124335_125124_+|twin-arginine-translocase-subunit-TatC	unknown	unknown	gnl|CDD|376413
NC_018145.1|WP_014848222.1|121830_122568_+|3-oxoacyl-ACP-reductase-FabG	unknown	unknown	gnl|CDD|187594
NC_018145.1|WP_014848231.1|133212_134559_+|glutathione-disulfide-reductase	unknown	unknown	gnl|CDD|235701
NC_018145.1|WP_012816905.1|126383_126518_-|entericidin-A/B-family-lipoprotein	unknown	unknown	gnl|CDD|227797
NC_018145.1|WP_012816903.1|122717_123380_+|hypothetical-protein	unknown	unknown	unknown
NC_018145.1|WP_014848227.1|126884_128537_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226434
NC_018145.1|WP_014848224.1|123880_124339_+|twin-arginine-translocase-subunit-TatB	unknown	unknown	gnl|CDD|130477
NC_018145.1|WP_014500340.1|135026_136985_+|potassium-transporter-Kup	unknown	unknown	gnl|CDD|225700
NC_018145.1|WP_014848228.1|128563_128776_-|hypothetical-protein	unknown	unknown	gnl|CDD|375983
NC_018145.1|WP_011241043.1|119706_119931_-|30S-ribosomal-protein-S18	unknown	unknown	gnl|CDD|178997
NC_018145.1|WP_014848233.1|138831_139782_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176153
NC_018145.1|WP_014848232.1|137772_138762_-|carbon-nitrogen-hydrolase-family-protein	unknown	unknown	gnl|CDD|143588

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018145.1|WP_014848230.1|131526_133050_+|glucose-6-phosphate-isomerase	gnl|CDD|366041	pfam00342, PGI, Phosphoglucose isomerase. Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.	0
NC_018145.1|WP_014848223.1|123532_123796_+|twin-arginine-translocase-TatA/TatE-family-subunit	gnl|CDD|234822	PRK00720, tatA, twin-arginine translocase TatA/TatE family subunit.	2.85691e-36
NC_018145.1|WP_011241032.1|130769_131195_-|hypothetical-protein	gnl|CDD|227505	COG5178, PRP8, U5 snRNP spliceosome subunit [RNA processing and modification].	0.000693568
NC_018145.1|WP_011241044.1|119062_119692_-|50S-ribosomal-protein-L9	gnl|CDD|234659	PRK00137, rplI, 50S ribosomal protein L9; Reviewed.	4.06061e-62
NC_018145.1|WP_011241045.1|117990_118986_+|dipeptide-epimerase	gnl|CDD|239435	cd03319, L-Ala-DL-Glu_epimerase, L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of the murein peptide of peptidoglycan, of which L-Ala-D-Glu is a component. L-Ala-D/L-Glu epimerase is a member of the enolase-superfamily, which is characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.	1.39911e-117
NC_018145.1|WP_011241042.1|119951_120326_-|30S-ribosomal-protein-S6	gnl|CDD|179034	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed.	6.50436e-48
NC_018145.1|WP_014848229.1|129121_130642_-|DEAD/DEAH-box-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	1.24424e-157
NC_018145.1|WP_014848221.1|120825_121761_+|ACP-S-malonyltransferase	gnl|CDD|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	7.76648e-125
NC_018145.1|WP_014848225.1|124335_125124_+|twin-arginine-translocase-subunit-TatC	gnl|CDD|376413	pfam00902, TatC, Sec-independent protein translocase protein (TatC). The bacterial Tat system has a remarkable ability to transport folded proteins even enzyme complexes across the cytoplasmic membrane. It is structurally and mechanistically similar to the Delta pH-driven thylakoidal protein import pathway. A functional Tat system or Delta pH-dependent pathway requires three integral membrane proteins: TatA/Tha4, TatB/Hcf106 and TatC/cpTatC. The TatC protein is essential for the function of both pathways. It might be involved in twin-arginine signal peptide recognition, protein translocation and proton translocation. Sequence analysis predicts that TatC contains six transmembrane helices (TMHs), and experimental data confirmed that N- and C-termini of TatC or cpTatC are exposed to the cytoplasmic or stromal face of the membrane. The cytoplasmic N-terminus and the first cytoplasmic loop region of the Escherichia coli TatC protein are essential for protein export. At least two TatC molecules co-exist within each Tat translocon.	4.28952e-76
NC_018145.1|WP_014848222.1|121830_122568_+|3-oxoacyl-ACP-reductase-FabG	gnl|CDD|187594	cd05333, BKR_SDR_c, beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs. This subgroup includes the Escherichai coli K12 BKR, FabG. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet) NAD(P)(H) binding region and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H) binding pattern: TGxxxGxG in classical SDRs. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P) binding motif and an altered active site motif (YXXXN). Fungal type type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P) binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr-151 and Lys-155, and well as Asn-111 (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	1.68747e-123
NC_018145.1|WP_014848231.1|133212_134559_+|glutathione-disulfide-reductase	gnl|CDD|235701	PRK06116, PRK06116, glutathione reductase; Validated.	0
NC_018145.1|WP_012816905.1|126383_126518_-|entericidin-A/B-family-lipoprotein	gnl|CDD|227797	COG5510, COG5510, Predicted small secreted protein [Function unknown].	3.83263e-06
NC_018145.1|WP_014848227.1|126884_128537_-|sensor-histidine-kinase	gnl|CDD|226434	COG3920, COG3920, Signal transduction histidine kinase [Signal transduction mechanisms].	9.9023e-20
NC_018145.1|WP_014848224.1|123880_124339_+|twin-arginine-translocase-subunit-TatB	gnl|CDD|130477	TIGR01410, Sec-independent_protein_translocase_protein_tatB., twin arginine-targeting protein translocase TatB. This model represents the TatB protein of a Sec-independent system for transporting folded proteins, often with a bound redox cofactor, across the bacterial inner membrane. TatC is the multiple membrane spanning component. TatB, like the related TatA/E proteins, appears to span the membrane one time. The tat system recognizes proteins with an elongated signal sequence containing a conserved R-R in a motif approximated by RRxFLK N-terminal to the transmembrane helix. TIGRFAMs model TIGR01409 describes this twin-Arg signal sequence. A similar system, termed Delta-pH-dependent transport, operates on chloroplast-encoded proteins. [Protein fate, Protein and peptide secretion and trafficking].	3.50777e-18
NC_018145.1|WP_014500340.1|135026_136985_+|potassium-transporter-Kup	gnl|CDD|225700	COG3158, Kup, K+ transporter [Inorganic ion transport and metabolism].	0
NC_018145.1|WP_014848228.1|128563_128776_-|hypothetical-protein	gnl|CDD|375983	pfam18557, NepR, Anti-sigma factor NepR. The general stress response sigma factor in alphaproteobacteria, sigma EcfG is inactivated by the anti-sigma factor NepR, which is itself regulated by the response regulator PhyR. NepR forms two helices that extend over the surface of the PhyR subdomains. Homology modeling and comparative analysis of NepR, PhyR and sigmaEcfG mutants indicate that NepR contacts both proteins with the same determinants, showing sigma factor mimicry at the atomic level. This entry represents NepR domains found in alphaproteobacteria.	1.41305e-06
NC_018145.1|WP_011241043.1|119706_119931_-|30S-ribosomal-protein-S18	gnl|CDD|178997	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed.	2.27745e-35
NC_018145.1|WP_014848233.1|138831_139782_+|LysR-family-transcriptional-regulator	gnl|CDD|176153	cd08464, PBP2_DntR_like_2, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold. This CD includes an uncharacterized LysR-type transcriptional regulator similar to DntR, NahR, and LinR, which are involved in the degradation of aromatic compounds. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.75119e-76
NC_018145.1|WP_014848232.1|137772_138762_-|carbon-nitrogen-hydrolase-family-protein	gnl|CDD|143588	cd07564, nitrilases_CHs, Nitrilases, cyanide hydratase (CH)s, and similar proteins (class 1 nitrilases). Nitrilases (nitrile aminohydrolases, EC:3.5.5.1) hydrolyze nitriles (RCN) to ammonia and the corresponding carboxylic acid. Most nitrilases prefer aromatic nitriles, some prefer arylacetonitriles and others aliphatic nitriles. This group includes the nitrilase cyanide dihydratase (CDH), which hydrolyzes inorganic cyanide (HCN) to produce formate. It also includes cyanide hydratase (CH), which hydrolyzes HCN to formamide. This group includes four Arabidopsis thaliana nitrilases (Ath)NIT1-4. AthNIT1-3 have a strong substrate preference for phenylpropionitrile (PPN) and other nitriles which may originate from the breakdown of glucosinolates. The product of PPN hydrolysis, phenylacetic acid has auxin activity. AthNIT1-3 can also convert indoacetonitrile to indole-3-acetic acid (IAA, auxin), but with a lower affinity and velocity. From their expression patterns, it has been speculated that NIT3 may produce IAA during the early stages of germination, and that NIT3 may produce IAA during embryo development and maturation. AthNIT4 has a strong substrate specificity for the nitrile, beta-cyano-L-alanine (Ala(CN)), an intermediate of cyanide detoxification. AthNIT4 has both a nitrilase activity and a nitrile hydratase (NHase) activity, which generate aspartic acid and asparagine respectively from Ala(CN). NHase catalyzes the hydration of nitriles to their corresponding amides. This subgroup belongs to a larger nitrilase superfamily comprised of belong to a larger nitrilase superfamily comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13), this subgroup corresponds to class 1.	1.09347e-151

Protein sequences

>NC_018145.1|WP_014848225.1|124335_125124_+|twin-arginine-translocase-subunit-TatC
MSETDDIHDEVDESAAPLLDHLLELRKRLLISLVALGIAFLLCLHFSRSIFAFLVQPLLRAGQGRLIYTDIFEAFFVDIKVAFFAAIMLAFPIVAMQIWRFIAPGLYNNEKRAFLPFLVMTPLLFLVGASMAYYVAMPIALHFLLGYQGNIGGVQQTALPAVGNYLNFVTKFIFGFGVAFLLPLVLLLLERAGFVTRQQLVAGRRYAIVASVAIAAVLTPPDIVSQLLLGVPLILLYEMALLAMLFGEKRRKKETDLVVAED
>NC_018145.1|WP_014848224.1|123880_124339_+|twin-arginine-translocase-subunit-TatB
MFDVAPSELLLVAVVALVVIGPKDLPRAMRVVGRWLGKARKLSRHFRSGIDEMIRQSEMEDMEKRWAEENAKLLAENQGQGNQTASTSSPATQSPASDDPAEQNIVFASPADLEVNTADTNYLAAHHTETAATTAASTPATPKEADQQEKQS
>NC_018145.1|WP_014848223.1|123532_123796_+|twin-arginine-translocase-TatA/TatE-family-subunit
MGGMSITHWIVVAVVVMIFFGKGRFSDMMGDVAKGIKSFKKGMSEDDSTPPAAPPAPAPRLENQPLPPENTPQNVAQNVPNDIKNNQ
>NC_018145.1|WP_012816903.1|122717_123380_+|hypothetical-protein
MSIFKSGFAPVITLSLASLLLGGCVVHHGQFDEMGSMTVRRSSCPAVAVPDYTGDVTLFNPSDQRTASAIDIEAVITKLRPKCDDTASGPVVTHLTFTVQARRRHVGGARDITLPYFVAVMRAGTRLLSKEMGTVRIHFEPGQMATDTEVTTSSAIDHDSATLPRDIIRQLNKVRQVTDVDASVDPTNDPKVRAAMKEASFEMLVGFQLTEPQLAYNATR
>NC_018145.1|WP_014848222.1|121830_122568_+|3-oxoacyl-ACP-reductase-FabG
MFDLNGLTALVTGASGGIGSAIAKALADQGVQVALSGTRESALKEVAAILPNDPIILPANLGQKEDVEQLVPRALEKLGKIDILVNNAGITRDGLMMRMKDEDWADVIALNLESVFRLSRAVIRPMMKTRFGRIINISSVVGQTGNAGQANYAAAKAGMIGMSKSLAREVASRGITVNCIAPGFIETKMTDILTEQQKEAAKSQIPAGRFGDIQDIAAAAVYLASKEAGYMTGQTLSVNGGMSML
>NC_018145.1|WP_014848221.1|120825_121761_+|ACP-S-malonyltransferase
MRAFIFPGQGSQSVGMGQALFDASLAARHVFEEVDEALKQNLFRLMSQGPEEELRLTENAQPAIMAHSMAVLAMLEKEGNIRLTDAASFVAGHSLGEYSALAAADAFDLPTTARLLKKRGQAMQAAVPVGEGGMAAILGLDFETVESIAKEAAEKDICQAANDNAPGQVVISGSLAAIERAVALAKEKGARRAVMLDVSAPFHCSLMQPAADVMAKALQENRPRQPIVPVFANVSATAETDPTKIMNLLVEQVTGRVRWRESIAAMAAAGVEEFVEFGGKVLTPMIKRIAPDCKATSLIAPADIENFAASL
>NC_018145.1|WP_011241042.1|119951_120326_-|30S-ribosomal-protein-S6
MPLYEHVFLARQDLAQTQVDGLAATATSIIEEKSGKVVKTEIWGLRNLAYRIQKNRKAYYIMLEIDAPADAIQELERQMALNEDVIRYMTVRVDAHEQGPSAMMRRGDRDRSNRSDRRRDRDAA
>NC_018145.1|WP_011241043.1|119706_119931_-|30S-ribosomal-protein-S18
MARPFFRRRKSCPFAAKDAPKIDYKDVRLLQGFVSERGKIVPSRITAVSAKKQRELARAIKRARHIGLLPFIVK
>NC_018145.1|WP_011241044.1|119062_119692_-|50S-ribosomal-protein-L9
MDVILLERIEKLGHIGDVVAVKNGYARNFLLPRKKALRANEANRKIFEANRAQIEADNAARRTDAEKESEVVNGLTVTLIRQASNTGHLYGSVSARDLADAIVEAKPEAKVAKNQIVLDRPIKSIGISEVRVVLHPEVAVKIKVNVARSPEEAELQAEGVDVMNQMFERDGASFTEDYDPNAEPGLATEAEEAVADADDNAETNSEESL
>NC_018145.1|WP_011241045.1|117990_118986_+|dipeptide-epimerase
MTATRSLSIMGESLPLKTPFRISRGVKNTIDTIVANISESGVTGRGEGIPYPRYGQTVESALIEANSVSHKITEHYGREALLTLLPPGPARNALDCALWDIEARISGQSVASMMGIAKLEPLATAVTISLDEPEVMAKAAAKLAYCPVIKVKVDEHNPEDCIKAVRDQAPKARLIVDPNESWSFDLLDKMQNFLADARVALLEQPLAAGADEALKGFSPAVPICADEVFHSADDLDHIADRYQVINIKLDKTGGLTAAIDIMKQARSLNLSIMVGCMVCSSLSLAPAFHLAAQADFVDLDGADWLVHDRNDGMLLDNGILHPPSATFWGGP
>NC_018145.1|WP_012816905.1|126383_126518_-|entericidin-A/B-family-lipoprotein
MRILIHCLMASAVLALAACNTVQGFGQDLSSAGQSMSNSAERNK
>NC_018145.1|WP_014848227.1|126884_128537_-|sensor-histidine-kinase
MKAFFKKSPSKTPHKKQLLTRRLFLLFVSMPTWFRMLVVLSLAQLPPSFVALGAFIASSHQYRLNHQKETQLIATESARTIDDSVDILAYDVRNIFDEEGSYDFADMGECSLLIQHMQSLGFVPVDYALMDISGRLLCKSDNFKVNRAVLLPFKLAGKNNFYNVDLLEDEGQLQFSFLGGHYPLSKYLIVGQIGRDSLLKIIERKVVPDGSALFLAQKSHLLPLISPKKPLLKQSHPVVIPTFDNSINLIYDNNLPPFRKVDLLFVLLPVLIWFMTASIGWVVIHYMLLCPLRRTQRAIVDYGKTGEIQKIKPASIGAAREIRQVSKAFYHVAVRLAAHERALRNALQHQKMLTREVHHRVKNNLQVVSSLLSIHSRRAETAKEKSAYATIQRRVNALAIVQRQYYNELDKGQGLDLSLLIKELVNGLQTSLQTFEKNFQIGTEIDQVFVPLEKAMPIAFILVEIVDFSLAVDPLLPITIILHRHRAEFENIPDHAGLEIRAEALKQLSSRKGNEVIRRIISAFGRQLGGESVEKEEDGYYYYDIDILPD
>NC_018145.1|WP_014848228.1|128563_128776_-|hypothetical-protein
MNGSMTAHNHKRPASQELPASSGNAAHADESAKQAEDRKNAIGFALRNVYQQTVEEAVPDDLLALLAKLN
>NC_018145.1|WP_014848229.1|129121_130642_-|DEAD/DEAH-box-helicase
MSDKDCRLFLVRYFMSFADLGLSKELLQAVAELGYEEPTPVQAAAIPSVLMMRDLIAVAQTGTGKTASFVLPMIDILAHGRCRARMPRSLILEPTRELAAQVAENFEKYGKYHKLSMSLLIGGVPMAEQQAALEKGVDVLIATPGRLLDLFERGKILLSSCEMLVIDEADRMLDMGFIPDIETICTKLPTSRQTLLFSATMPPAIKKLADRFLSNPKQIEISRPATANTQINQRLIEVSPRSKKKKLCDMLRAEKDHTAIIFCNRKTTVRQLATTLEQQGFSVGQIHGDMSQPERGSELERFKNGQISVLVASDIAARGLDVKGISHVFNFDVPTHPDDYIHRIGRTGRGGASGEALTFVTPADEEAITAIEKLMGVEIPRLGNRKKNAYPSKSEEAVSPKQAKPVQEKSAAPSPRKAPRKAETPKKLPEDRLDSVENDFPKNQATRNAASRPVSKARTQERALRPENLRRVKPVALETAIDWNGPIPPFLNYSVPKTTARNAKKD
>NC_018145.1|WP_011241032.1|130769_131195_-|hypothetical-protein
MPPRHFPHSGVMEIHLNVRNANGRNQRPLPPPPPPPDSPYNAPPPPPEAVWHEKKGPKCVSPEDIGAAAVSEKDSVDLMLKGGSRIRAHLEHCPALDFYSGFYVHAGRDGQICAKRDPVYARWGGECLINRFRVVEGVFKH
>NC_018145.1|WP_014848230.1|131526_133050_+|glucose-6-phosphate-isomerase
MARIANKAAIDAAWKQVSACPEKTLKQLFEEDSNRLSGLVVETAKLRFDFSKNHLDSQKLTAFKKLLEACDFDARRKALFAGEKINITEDRAVEHMAERGQGAPASVARAKEYHARMKTLIEAIDAGAFGEVKHLLHIGIGGSALGPKLLIDALTRESGRYDVAVVSNVDGQALEEVFKKFNPHKTLIAVASKTFTTAETMLNAESAIEWMKKHGVEDPQGRMIALTANPAKASEMGIDDTRILPFAESIGGRYSLWSSIGFPAALALGWEGFQQLLEGGAAMDRHFLEAAPEKNAPILAAFADQYYSAVRGAQTHGIFAYDERLQLLPFYLQQLEMESNGKRVDLDGNLIDHPSAFITWGGVGTDAQHAVFQLLHQGTRLVPIEFIAAIKADDTLNPVHHKTLLTNAFAQGAALMSGRDNKDPARSYPGDRPSTTILMEELRPAQLGALIAFYEHRTFTNGVLLGINSFDQFGVELGKEMAHAIADHPENSDFDPSTKALIAAALK
>NC_018145.1|WP_014848231.1|133212_134559_+|glutathione-disulfide-reductase
MTDYDFDLFVIGAGSGGVRASRIAASHGASVAIAEEYRIGGTCVIRGCVPKKMLYYAADFAADLKKAQRFGWTLPEKKFDWATLRDVVLSDVKRLEGLYTQTLDNNHITHYKEHAVIEGANQIRLASGKKITARYILVAVGAEPAKLDIPGAEYAVTSNEMFLLPSLPKRALVVGGGYIANEFAGILNSFGVETTIATHGDRILRGYDEEIAARLVEIGQEHGIDYRFNADIARIDKDSSGHFTTHFKDGSQIESDLVLFAIGRVAKSRDLGLDKADVKTNDRGAILVNEENRTSCPSIYAVGDVTDRVQLTPVAIREGQAFADRVFGHKAASVDYDTIPTAVFSHPPLASAGLTEEEAKKRYKNIKIYKSTFRPMRNALIDSPDRALYKMVVDGDSDKVLGLHLIGQDSPEIIQLAAVAIKAGLTKQAFNDTVALHPSSAEELVLMR
>NC_018145.1|WP_014500340.1|135026_136985_+|potassium-transporter-Kup
MSNDTSPGTSSVDSKSSDPSYGVPGHSHSDKDLLKLSLGAIGIVFGDIGTSPLYALKECFKGHHQLPVDDFHIYGLVSLIFWTMGLVVTVKYVMFIMKADNKGEGGSMSLLSLIIRGANPKLSRWLIVLGVFATALFYGDSMITPAMSVLSAVEGLTVIEPSFDSWVPPVSVVILIGLFCIQARGTESVGRLFGPIMLVYFATLAILGAFNIITRSPAILLALNPYYAIHFFVSDPLQGFWALGSVVLSVTGAEALYADMGHFGRQPISLGWYWVVFPALTLNYLGQCALLSADHEAIANPFYFLAPDFLRVPLIILATFAAVIASQAVITGAFSVTQQAIQLGYIPRLRVNHTSASTVGQIYIPSVNWVLMFMVMVLIAMFKNSTNLANAYGIAVTGTMFITSCMMGVLVHRVWHWKAWQSIPLVSFFLLIDGAFFLSNVTKIPEGGWFPLLVGFVVFTMLMTWSRGRHLMAERMRQVAMPIQLFIRSAAASAVRIPGTAIFLTPEDDGVPHALLHNLKHNKILHERVILLTVKIEDVPYVDPHYRASMSSLEDGFYRLIVRYGFMEEPDVPLALNKIEQSGPMLRMDDTSFFISRQTLIPSTHTSMAIWREKLFAWMLRNSESATEFFKLPSNRVVELGSQIELVGSNGK
>NC_018145.1|WP_014848232.1|137772_138762_-|carbon-nitrogen-hydrolase-family-protein
MSCHRVAVIQAGTSLFDTEKTLDRMEALCRQAAEQNVELAVFPEAYIGGYPKGLDFGARMGTRTEAGREDFLRYWKAAIDVPGKETARIGSFAAKMKAYLVVGVIERSEATLYCTALFFAPDGTLIGKHRKLMPTATERLVWGQGDGSTIEILDTAVGKLGAAICWENYMPALRQVMYAGGVNIWCAPTVDQRKIWQVSMRHIAYEGRLFVLSACQYMTRADAPADYDCIQGDDPETELIAGGSVIIDPMGNILAGPLYGQEGVLVADIDLSDTIKARYDLDVSGHYGRPDIFEIKVDRQSHQVIRDQFSRDQATEKKPVSDSAISQLD
>NC_018145.1|WP_014848233.1|138831_139782_+|LysR-family-transcriptional-regulator
MIRKINISDITRFDFNLVITFLALWHERSVTKAAARLSLSQSAVSASLSRLRQAADDLLFIRTRQGMEPTQRAIDMVESLSEGATLIYNAFISENEFDPARCNRHFSIGMSDDFQLALGSEISKQIQAIAPDASVVYRQTNRYTAQQMLENNDIDLAIVTASLPRRGLWQEVIGEGGYACLCDAQSCGFSENPILEAYLSLPHILVSYSGREGLVDEILSIMGRSRKIQTALTHFAALPPFLLGSKSIATIPSHAAISLAGYTGLTIFEAPLELTAYPIIATMRLSSQKDTALLWLFQIIKQAIRVQRNILPPPQS

Crispr_ID: NC_018145_2

• CRISPR_ID: NC_018145_2
• CRISPR_location: 1235874-1236083
• CRISPR_type: Orphan
• Repeat_type: I-F
• Spacer_info: 3 spacers

Consensus repeat of NC_018145_2

Consensus_repeat	Method
GTTTCTAAGCTGCCTGTGCGGCAGTGAACT	PILER-CR
AGTTCACTGCCGCACAGGCAGCTTAGAAA	CRT
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRISPRCasFinder

spacers of NC_018145_2

>2.1|1235904|31|NC_018145|PILER-CR
TGATCGGCAATATTCGACGGATCAACAGGCT
>2.2|1235965|30|NC_018145|PILER-CR
GCCATAGAATTGCAGAATTTGTCGGACACA
>2.3|1235903|32|NC_018145|CRT
CTGATCGGCAATATTCGACGGATCAACAGGCT
>2.4|1235964|31|NC_018145|CRT
CGCCATAGAATTGCAGAATTTGTCGGACACA
>2.5|1236024|31|NC_018145|CRT
TGAATACTGTCAAAGCTAACGGATTGAAATC
>2.6|1235903|33|NC_018145|CRISPRCasFinder
CTGATCGGCAATATTCGACGGATCAACAGGCTG
>2.7|1235964|32|NC_018145|CRISPRCasFinder
CGCCATAGAATTGCAGAATTTGTCGGACACAA
>2.8|1236024|32|NC_018145|CRISPRCasFinder
TGAATACTGTCAAAGCTAACGGATTGAAATCA

CRISPR arrays and Neighbor proteins around NC_018145_2

CRISPR arrays

The CRISPR arrays of NC_018145_2

>merge|NC_018145|2|1235874-1236083|PILER-CR,CRT,CRISPRCasFinder
AGTTCACTGCCGCACAGGCAGCTTAGAAACTGATCGGCAATATTCGACGGATCAACAGGCTGGTTCACTGCCGCACAGGCAGCTTAGAAACGCCATAGAATTGCAGAATTTGTCGGACACAAGTTCACTGCCGCACAGGCAGCTTAGAAATGAATACTGTCAAAGCTAACGGATTGAAATCAGTTCACTGCCGCACAGGCAGCATCAAAT

>NC_018145|2|2|1235874-1236024|PILER-CR
AGTTCACTGCCGCACAGGCAGCTTAGAAAC	TGATCGGCAATATTCGACGGATCAACAGGCT
GGTTCACTGCCGCACAGGCAGCTTAGAAAC	GCCATAGAATTGCAGAATTTGTCGGACACA
AGTTCACTGCCGCACAGGCAGCTTAGAAAT

>NC_018145|2|2|1235874-1236083|CRT
AGTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATCGGCAATATTCGACGGATCAACAGGCT
GGTTCACTGCCGCACAGGCAGCTTAGAAA	CGCCATAGAATTGCAGAATTTGTCGGACACA
AGTTCACTGCCGCACAGGCAGCTTAGAAA	TGAATACTGTCAAAGCTAACGGATTGAAATC
AGTTCACTGCCGCACAGGCAGCATCAAAT

>NC_018145|2|2|1235875-1236083|CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATCGGCAATATTCGACGGATCAACAGGCTG
GTTCACTGCCGCACAGGCAGCTTAGAAA	CGCCATAGAATTGCAGAATTTGTCGGACACAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	TGAATACTGTCAAAGCTAACGGATTGAAATCA
GTTCACTGCCGCACAGGCAGCATCAAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018145.1|WP_014848980.1|1229749_1230694_+|metallophosphoesterase	unknown	unknown	gnl|CDD|277347
NC_018145.1|WP_014848992.1|1243708_1245346_-|hydroxylamine-reductase	unknown	unknown	gnl|CDD|235391
NC_018145.1|WP_014848990.1|1241155_1242223_-|tRNA-dihydrouridine-synthase	unknown	unknown	gnl|CDD|239204
NC_018145.1|WP_014848985.1|1237166_1238750_+|ATP-binding-protein	unknown	unknown	gnl|CDD|223510
NC_018145.1|WP_014848984.1|1236680_1237154_+|Cys-tRNA(Pro)-deacylase	unknown	unknown	gnl|CDD|237976
NC_018145.1|WP_014848972.1|1222734_1223343_-|sel1-repeat-family-protein	unknown	unknown	gnl|CDD|276807
NC_018145.1|WP_181406048.1|1227518_1227668_-|hypothetical-protein	unknown	unknown	unknown
NC_018145.1|WP_014848975.1|1225157_1225982_-|sel1-repeat-family-protein	unknown	unknown	gnl|CDD|276807
NC_018145.1|WP_014848988.1|1239539_1240889_-|replication-associated-recombination-protein-A	unknown	unknown	gnl|CDD|237355
NC_018145.1|WP_014848993.1|1246048_1246885_-|aminotransferase-class-IV	unknown	unknown	gnl|CDD|238800
NC_018145.1|WP_014848973.1|1223533_1224259_-|sel1-repeat-family-protein	unknown	unknown	gnl|CDD|276807
NC_018145.1|WP_014848983.1|1234478_1235438_+|S1/P1-nuclease	unknown	unknown	gnl|CDD|367008
NC_018145.1|WP_014848994.1|1246850_1247462_-|aminodeoxychorismate/anthranilate-synthase-component-II	unknown	unknown	gnl|CDD|235552
NC_018145.1|WP_014848982.1|1231968_1234461_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|238657
NC_018145.1|WP_014848974.1|1224366_1224975_-|sel1-repeat-family-protein	unknown	unknown	gnl|CDD|276807
NC_018145.1|WP_014848991.1|1242383_1243550_-|Na+/H+-antiporter-NhaA	unknown	unknown	gnl|CDD|377746
NC_018145.1|WP_011240085.1|1245411_1245849_-|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224870
NC_018145.1|WP_014848981.1|1230851_1231646_+|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239491
NC_018145.1|WP_014848979.1|1228423_1229242_-|sel1-repeat-family-protein	unknown	unknown	gnl|CDD|276807
NC_018145.1|WP_014848986.1|1239017_1239350_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018145.1|WP_014848980.1|1229749_1230694_+|metallophosphoesterase	gnl|CDD|277347	cd07402, MPP_GpdQ, Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain. GpdQ (glycerophosphodiesterase Q, also known as Rv0805 in Mycobacterium tuberculosis) is a binuclear metallophosphoesterase from Enterobacter aerogenes that catalyzes the hydrolysis of mono-, di-, and triester substrates, including some organophosphate pesticides and products of the degradation of nerve agents. The GpdQ homolog, Rv0805, has 2',3'-cyclic nucleotide phosphodiesterase activity. GpdQ and Rv0805 belong to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	2.49994e-18
NC_018145.1|WP_014848992.1|1243708_1245346_-|hydroxylamine-reductase	gnl|CDD|235391	PRK05290, PRK05290, hybrid cluster protein; Provisional.	0
NC_018145.1|WP_014848990.1|1241155_1242223_-|tRNA-dihydrouridine-synthase	gnl|CDD|239204	cd02810, DHOD_DHPD_FMN, Dihydroorotate dehydrogenase (DHOD) and Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires FMN as co-factor. DHOD divides into class 1 and class 2 based on their amino acid sequences and cellular location. Members of class 1 are cytosolic enzymes and multimers while class 2 enzymes are membrane associated and monomeric. The class 1 enzymes can be further divided into subtypes 1A and 1B which are homodimers and heterotetrameric proteins, respectively. DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN and eight [4Fe-4S] clusters, arranged in two electron transfer chains that pass its homodimeric interface twice. Two of the Fe-S clusters show a hitherto unobserved coordination involving a glutamine residue.	3.80678e-101
NC_018145.1|WP_014848984.1|1236680_1237154_+|Cys-tRNA(Pro)-deacylase	gnl|CDD|237976	cd00002, YbaK_deacylase, This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS) inserted (INS) editing domain. The bacterial amino acid trans-editing enzyme YbaK is a deacylase that hydrolyzes cysteinyl-tRNA(Pro)'s mischarged by prolyl-tRNA synthetase. YbaK also hydrolyzes glycyl-tRNA's, alanyl-tRNA's, seryl-tRNA's, and prolyl-tRNA's. YbaK is homologous to the INS domain of prolyl-tRNA synthetase (ProRS) as well as the trans-editing enzyme ProX of Aeropyrum pernix which hydrolyzes alanyl-tRNA's and glycyl-tRNA's.	3.98562e-68
NC_018145.1|WP_014848972.1|1222734_1223343_-|sel1-repeat-family-protein	gnl|CDD|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	6.69083e-41
NC_018145.1|WP_014848985.1|1237166_1238750_+|ATP-binding-protein	gnl|CDD|223510	COG0433, COG0433, HerA helicase [Replication, recombination, and repair].	2.00083e-14
NC_018145.1|WP_014848975.1|1225157_1225982_-|sel1-repeat-family-protein	gnl|CDD|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	1.99619e-43
NC_018145.1|WP_014848988.1|1239539_1240889_-|replication-associated-recombination-protein-A	gnl|CDD|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NC_018145.1|WP_014848993.1|1246048_1246885_-|aminotransferase-class-IV	gnl|CDD|238800	cd01559, ADCL_like, ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate. Based on the information available from the crystal structure, most members of this subgroup are likely to function as dimers. The enzyme from E.Coli, the structure of which is available, is a homodimer that is folded into a small and a larger domain. The coenzyme pyridoxal 5; -phosphate resides at the interface of the two domains that is linked by a flexible loop. Members of this subgroup are found in Eukaryotes and bacteria.	1.63976e-67
NC_018145.1|WP_014848973.1|1223533_1224259_-|sel1-repeat-family-protein	gnl|CDD|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	2.73621e-45
NC_018145.1|WP_014848983.1|1234478_1235438_+|S1/P1-nuclease	gnl|CDD|367008	pfam02265, S1-P1_nuclease, S1/P1 Nuclease. This family contains both S1 and P1 nucleases (EC:3.1.30.1) which cleave RNA and single stranded DNA with no base specificity.	3.12662e-93
NC_018145.1|WP_014848994.1|1246850_1247462_-|aminodeoxychorismate/anthranilate-synthase-component-II	gnl|CDD|235552	PRK05670, PRK05670, anthranilate synthase component II; Provisional.	2.38229e-98
NC_018145.1|WP_014848982.1|1231968_1234461_+|TonB-dependent-receptor	gnl|CDD|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	1.86737e-38
NC_018145.1|WP_014848974.1|1224366_1224975_-|sel1-repeat-family-protein	gnl|CDD|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	6.50203e-42
NC_018145.1|WP_014848991.1|1242383_1243550_-|Na+/H+-antiporter-NhaA	gnl|CDD|377746	pfam06965, Na_H_antiport_1, Na+/H+ antiporter 1. This family contains a number of bacterial Na+/H+ antiporter 1 proteins. These are integral membrane proteins that catalyze the exchange of H+ for Na+ in a manner that is highly dependent on the pH.	6.52071e-137
NC_018145.1|WP_011240085.1|1245411_1245849_-|Rrf2-family-transcriptional-regulator	gnl|CDD|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	7.93449e-32
NC_018145.1|WP_014848981.1|1230851_1231646_+|phosphatase-PAP2-family-protein	gnl|CDD|239491	cd03397, PAP2_acid_phosphatase, PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains to be determined.	1.09364e-92
NC_018145.1|WP_014848979.1|1228423_1229242_-|sel1-repeat-family-protein	gnl|CDD|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	1.57633e-41

Protein sequences

>NC_018145.1|WP_014848983.1|1234478_1235438_+|S1/P1-nuclease
MTDNRVSKLFKKRLTKLAIVAAMLTLPQPLYAWGREGHEAIAALAWKYMTPTTRKKVNAILAMDHDTLTEPDFMSRATWADKWRSAGHGETEPWHFVDIEIDNPNLVTACAATSNRSNPMKNGGAQPCVVSQLDRFERELSSKQTSDQDRVLALKYVLHFVGDLHQPLHAADHDDRGGNCVKVSINNARSLNLHSYWDTYVVKEIDPDPQHLADSLKKEISPEDKKSWVLGDSKQWAMESFQLGKRYAYSFNPPAGCDATRPPIPLSAGYDSAARKVAASQLKKAGVRLAYILNHRLRSIPLSYFLQAQKQDAATNNNG
>NC_018145.1|WP_014848982.1|1231968_1234461_+|TonB-dependent-receptor
MKNLLSAKTKSFLSFKQSRLNWVILYSSLWVSGAMAQNAVPPQPATDDTSSQQHAVTDNSANDPAKNDGAIVVTGRSYADGVTRRAFGGGLMIKEDSPKSKSTLTRDYIEKQTPGLNPMQLIALLPGVNSSDSDPMGLTGGHTSVRGMNESSMGYILEGFPLNDVGSHAIYPQEIVDSENLSTIQVAQGSADLDSPTVSAAGGVVNMHMIDPAKKMGGRANFTYGSYNTFRGFARFDTGEMGNSGTRAYFSFSDTHEDLWRGPGTEKKLHGEMKVVKEWGKDNKASLLVIGNQLDNYNMPSVNMASWQKYGKGIMGGPVSGIPNTVYSSVYTGNTKANTTYYKLHPNPFTNIYVSAPVHLNLGHKMTLTETPYYLYSNGNGGGAYWQDMNKMSYGSQTMSGTVDGQNYGQTLLYEPSITKTNRMGSTTKWTWTSGINRLMIGYWFEYSSQRQTAPYSLLNDDGSPRDKWGGGSNVILANGEKAEYRDNLTRTFIHTPFIGDTISLLNDKLTIDGGVKISIINRQGRNYLPDTSTGKNINQTYREVLPSGSIRYKINDEHQVFFSVATNYRIPMNTSLFDSGSYVAGTGYSNQAVKDLKPETSISEEFGWRYHGKLINTSLTYFHYDFHNRLFSQTVIDPNNPTSYYSRSINGGNQTTNGVDFEIGTRAIYNIRPYVSAEYIDARNRSNLAASAAGVSAILPTKGKFAPQTPRYQVGFGLDYDNGHIFGNFSLKYVGSQYSTFMNDEQVPSYVRMNIGGGYRFKSWGGLKSPTIRFNLSNITNKHYLNYASGLQTNAQYAKALDGQMVKGSAPTYSIASPFSAMFSISSGF
>NC_018145.1|WP_014848981.1|1230851_1231646_+|phosphatase-PAP2-family-protein
MIKVPRFICMIALTSSVLASGLSQSVSAHTEKSEPSSTYHFHSDPLLYLAPPPTSGSPLQAHDDQTFNSTRQLKGSTRWALATQDADLHLASVLKDYACAAGMNLDIAQLPHLANLIKRALRTEYDDIGRAKNNWNRKRPFVDTDQPICTEKDREGLGKQGSYPSGHTTIGWSVALILAELIPDHAANILQRGQIFGTSRIVCGAHWVSDVQAGYIMASGEIAALHGDADFRRDMELARKELEKARASAHTPDDLLCKIEQSAR
>NC_018145.1|WP_014848980.1|1229749_1230694_+|metallophosphoesterase
MISFNRRRFLSLSAGATFAAATAPRLYAGVPNRPPLRSHQSFTFVFITDTHLQPELNGAEGCREAFLKARQFPADFAIHGGDHVFDALGVNANRATMLADLYKRTANDLRLPVYNTMGNHDCFGIYKESGAQPTDPFYGKKYFQDNFGQTYYSFDHKGVHFVILDSIGITEDRSYEGRVDAEQFNWLSRDLAAQPVGTPIIVSTHIPIMNAIDYASVPLNKMKHHSLSVINAADILELFDHYNVIGVFQGHTHVVERVEWHGVPYITGGSVCGNWWHGTRYGTPEGFMVVKVEKGKVIPHYESYGFHTIDPRNT
>NC_018145.1|WP_014848979.1|1228423_1229242_-|sel1-repeat-family-protein
MKKILLLWVVVFSFVASRTQMQIRKELESFQSKYAALIKKPVQEKSSGRRLVVEKDSIPPDPPLHSQILLHPQEAAEKGDAEAQMFLGKAYLTGHSDVPKNSKQAVFWFQKSANQGYAEGEVALADAYHHGTGVGRDEAKAAFWYQKAAAQNNIEAEVRLGFVYHQGRGLPKDEKMSFFWFDKAAHQGSLLAQTMVGVAYYYGSGIPQDKGRAFMWYQKAAHQGDVMAQYLLGMAYLKGEGVARSERDGVFWLQRAAAQGDYNAFKILQRLQ
>NC_018145.1|WP_181406048.1|1227518_1227668_-|hypothetical-protein
MRKGWGGFLWGCPAFIDIRNWGQASFPNDLFYHGWLSGGALSVVVIPFE
>NC_018145.1|WP_014848975.1|1225157_1225982_-|sel1-repeat-family-protein
MKKFLFFTAVFLPFVANPVQAQTANSTKVVAGKTALSLEQKARAGNPKAQTDLGTAYYNGQGMAQDYKQAISWYQKAANQGYPLAQYYLGNACLQGIGLTQSDEQAVSWYQKAANQGLAEAQYSLAIAYYTGRGVTQNYGQASFWFQRSANQGFVPAQFYLGVMYRNGAGIPEDDDRALFWFHKAADKGYADAQYNLGLIYHEGKVVKKDEKQAAFWYQQAANQGLVEAEFNLGIAYLKGQGVQKDKDKATFWLEKAADKGDSHAQDVLEMMNK
>NC_018145.1|WP_014848974.1|1224366_1224975_-|sel1-repeat-family-protein
MKKRIILLGVLLSVGGQIVYSQVRKTPSIFSQKKLHELKQAADQGDAEAEAALGEAFDFGTITPQDYQKAFFWYQKAADQAVAEAQYNLGGLYYKGAGRPKDGEKAVYWYRKAADQGYIDAQRNLALLYAKGELVPQSDEQAVYWYQKAADQGNAEAQRALGSAYALGKGVPRNKEKALFWIGKAADQGDMEAQKLLAMLAR
>NC_018145.1|WP_014848973.1|1223533_1224259_-|sel1-repeat-family-protein
MFFVPFVVLSLSVSPLTMQADKERYDREMISSLEGRAKAGNSLAEEVLGEAYAHGRGRPQDDEKAVYWYQKAADKGMKESQYNLGNAYLYGRGVGIDYEKAAFWYRKAADQNFIQAQYNLGLLYEKGQGLPKSDEQAAFWWQKAAEQGEAKAQFNLGVFYHNGRAVPKNNVRAIFWMEQAAQQGLIDAQILLAMAYASGQGAPKDKNKAIYWYQKAADQGNIAAKEVLQTLSHYFVRGLKH
>NC_018145.1|WP_014848972.1|1222734_1223343_-|sel1-repeat-family-protein
MKRILLAAMFFPLVVHPVQAAGVRSTNKASSGNSIAEIQRNAEAGYADAQLKLWAAYYSGEGVAQDKEKAVFWYQKAANQGDAGAQFLLGRAYYLGDGVSQDYEKAVFWWQKSANQGIADAQYNLGLAYYNGAGMPKSDEKAVFWYQKAANQGYADAQLKLGAAYYFGKGVAQDKGTAHFWIQQAADKGNAKAKEYLSKLFN
>NC_018145.1|WP_014848984.1|1236680_1237154_+|Cys-tRNA(Pro)-deacylase
MTKKTRGTAFLEKAGIAFTVHPYDYDPKAPAAGLQAAEALQQPAEIVYKTLMTEVDGKPVCVVVQVNHEVSMKKLAAAAGGKSANMIKPVDAERMTGYHVGGISPFGQKKRVPVIFDESAFQAEKIFINGGQRGVLVALAPEDARRAVDGKIAAVAN
>NC_018145.1|WP_014848985.1|1237166_1238750_+|ATP-binding-protein
MAINKERDEPFSYLWQILLFLTDLPLQKRTSLAQRYRMTVMIDMGKDSKGQVVPMDLEELLATRLLVQGNSGSGKSHLLRRMLEKSARFVQQIVIDPEGDFVTLAERFPHVAVEAAAYNESEIRVLAQRIREHRVSVVLNLEGLDVDNQMKCAAWFLATLFDAPRDHWYPAIVVVDEAQIFAPAQAGEVSDEARRLSLAAMTNLMCRGRKRGLAGVIATQRLAKLAKNVAAEASNFLMGRTFLDIDMARAADLLGMDRRQAESIRDLERGHFLALGPALCRRPIAVKIGEVETKSRTGGFKLMPLPDSKNSNPEDLLFSEPEEPALPLASPEPPPPPSSSQLMELLQKEKEEEAKIAEAEAAENLVDNSQKEALIDALLSSIVEEEENAYRQANLLYPEFTIGCRMHGLSTPPLDLTTFTKRLTIAKAGLSNDDLQDELWQPALKAASILEDDIQAVFLFLAKTAKENAPCPDDEMIARIYGTRSAGRARRLIGYMENQGIIAIRTDFGGRRSITLPALGWTTSTAA
>NC_018145.1|WP_014848986.1|1239017_1239350_-|hypothetical-protein
MSHKKLEVSAGIRHRMAAEIMDHMNYMVDDPDQLSVKPANALEHIFLYEDSGAVIAEIPVVFKGESGRVLYDISHNRLVHSDIKHDQLKEMVSSKMPDFKEELLEYFREN
>NC_018145.1|WP_014848988.1|1239539_1240889_-|replication-associated-recombination-protein-A
MDDLFNSVEPLVFTENEKQPLPGNRPLADILRPKHLSDVIGQAHVTGENGIIGRMVAAGRLSSLILWGPPGTGKTSIAQLLAESVGMRFEMVSAIFSGVADLKKIFQNAATYREMGKQTLLFIDEIHRFNKGQQDSFLPYIENGTFVLVGATTENPSFALNAALLSRAQVVTLNRLDEEALGLLLERAETVSGQLLPVDEDARKALIASADGDGRFLLNQAEILLAMNLTKSLSVPELAQILQKRMAIYDKDRDGHYNLISALHKSVRGSDPQAALYYLSRMLVAGEDPLYLLRRLTRMANEEVGLADPRAMEQCIAAKETYQLLGSPEGELAIAQACVYVATAPKSNAIYKAYNQAMALARESGSVLPPPNILNAPTEMMKQQGYGEGYHYDHDMPDAFSGDNYWPENLPPVTLYQPNIRGYEKHITERLAFWAHLRQERKKGKPSGK
>NC_018145.1|WP_014848990.1|1241155_1242223_-|tRNA-dihydrouridine-synthase
MKTEIPYYNPELSYEDNYKEGPFGYFADIVEKPDPSFAVSVKKPVSFLGCSVDLPFGIPAGPLLNSRYIKAAFHAGFDLCVYKTVRTQEHKSHPLPNVLAIHPEGVLSADCEAVLADTRYNQPLSITNSFGVPSFNPDIWQPDMAEAVKAASDHQVMIGSFQGTRGKGKIEEDYALAARMVAETGAPVLEANLSCPNEGVNSLLCFDTLAVQKIVEAIKAAVPDRPLLIKTAYFKDNAKLADLVSRVGHLVSGFSTINTLSARPLDEKGQAALSPSRPEGGVCGEAIRWAGLEMVQRLAAFREEKSLDYAIVGVGGVNKPEHYKAYIEAGANAVMSATGSMWNPHLAEETKKFLA
>NC_018145.1|WP_014848991.1|1242383_1243550_-|Na+/H+-antiporter-NhaA
MRFSIRRFFSGASGGAIILLLSALLGLLLSNSFLSESYFKLLHLKMPFSALDDAPNLAEFISIAPMSLFFFVVIAEIKEEIISGHLASFRRVILPLISALGGMMIPACLYGLITSGHLEVSRGWAIPIATDAAFTLPIILALGRHVSEGGRVWLMALAIFDDLLGIVVIALFYASHLNGYALLAAGLIIAVMIGLNKKSVQNLWVYASAGVILWLALLVSGLHPTIAGVITGLALPSVANQPEKASPLERGKQIIAPWVTWLILPLFGFVSMGMSLSAMSFHVLLAPVPLGVALGLFLGKPIGVFGATIMATRLKIATLPKGTSLQMLFGLSLLCGIGFTISLFIAELAFSGSDFLVPAKYGILMGSLLSALAGWLWLRFLKFPAKGV
>NC_018145.1|WP_014848992.1|1243708_1245346_-|hydroxylamine-reductase
MLCFQCEQTHSGTGCVIRGVCTKTPEVAAIQDLMIFASAGLSYVAKKLPDSCEAERKEAASLVIQALFSTVTNVNFDADVLTKALYHLVDFRDALKAKLPEDVELPLAATLDFSRDRETLVKQGESYGIASRQKTLGIDVTGLQELLTYGMKGMAAYAHHAAVLDYRDPDVDNFLLEGMAALTDHSLDIQALLAVVMRCGEASYKTLALLDKANTSSFGHPVPTNVKMGPSKGKAILVSGHDLLDMKELLEQTKDTGIKVYTHGEMLPAHGYPELNKYPHLAGHYGGAWMLQRQEFINFPGPIVMTTNCLMEPRKEYAGRVFTRDLVGWPGLTHLPDRDFSKVIEAALESEGFTEDHESRSHIAGFGHHTVLDSADAVVSAIKKGDIKHFMLVGGCDGIKSGRHYFTDIAEKAPKDWVILTLGCGKFRVTDLDLGKIGDLPRLLDMGQCNDSYSAIRVALALADAFDTDVNSLPLSLVLSWYEQKAVCVLLALLHLGVKGIRLGPTLPAFITPNMLKILVDNFDIKPIGNSAEEDLQEILAAKAA
>NC_018145.1|WP_011240085.1|1245411_1245849_-|Rrf2-family-transcriptional-regulator
MLSISQSTGYAVLALSAIHAESEKLTMARDIAEKANIPRPYLTKILGRLQEAGLITAKRGQNGGLRLNRPPETISLLEIVKAIDGKDWGCGCFLGLPGCSNEHPCPMHSFWLKTRPVIVKQLENMTLDKAKHFTEAGWKFRSEEG
>NC_018145.1|WP_014848993.1|1246048_1246885_-|aminotransferase-class-IV
MPIWLNGVLANNTVAEFNLNDKGLLLGYGVFDTALVIADKVAYREAHLEKLTKSCAALSLPVASSFLSEMMEKAAKDLPLGVIRITVTGGVGPRGMAFSPEAKPNVIVSGSPISPTIFCPEIRLVLTPLRRNESSFTSQIKTLNYLDAIMAVTEARQKSFDDALFLNTAGHVACSSTANLFMIRDGCLITPPVSDGILAGIMRANILRFAKSRDIPVEERSICYEELLEADDIFLTNSLRLISQVTHLGEVALPRRSAALLALLESMVFDEINYSRSQ
>NC_018145.1|WP_014848994.1|1246850_1247462_-|aminodeoxychorismate/anthranilate-synthase-component-II
MLLMIDNYDSFVVNLARYCERLGRKVSLFRHDKITLEEIEVMSPKAIILSPGPCSPEEAGISLDVLRQFSGKIPILGVCLGHQAIGVAFGGVIARASYPLHGRAMEISHVGKRLFKDIPNPFKAARYNSLIIQKTEEMEQHLTVDALSPEGEIMALSHKSHPTYGIQFHPESVLTEYGDALLSRFFDLEEAFYADMAERCISQ

Crispr_ID: NC_018145_3

• CRISPR_ID: NC_018145_3
• CRISPR_location: 1756727-1757238
• CRISPR_type: Orphan
• Repeat_type: I-F
• Spacer_info: 8 spacers

Consensus repeat of NC_018145_3

Consensus_repeat	Method
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CRT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	PILER-CR

spacers of NC_018145_3

>3.1|1756755|32|NC_018145|CRISPRCasFinder,CRT
GTAAAAGTCGGACAATACCTTCAGATCAATCA
>3.2|1756815|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR
CAAGCTATAGCAAAATTGGAAAAGACAAATGC
>3.3|1756875|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR
ATAAATATATCGGCATTCGCTGTCGGGCAGCT
>3.4|1756935|33|NC_018145|CRISPRCasFinder,CRT,PILER-CR
TGCATCTTGATGTCGGAGCTGGTCTGATCGACT
>3.5|1756996|33|NC_018145|CRISPRCasFinder,CRT,PILER-CR
GACCCGTTCTGCGGCACCATGCCGAGAAGCTGT
>3.6|1757057|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR
GTGAGTCACTCGGTAAGAACCATTTTTTATCA
>3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR
GTAAATCAGCTGGAATTGTCGCTGACTGGATA
>3.8|1757177|34|NC_018145|CRISPRCasFinder,CRT,PILER-CR
ATTACGCCGGTCTCCTGTCCAAAATTCGTAAGCC

CRISPR arrays and Neighbor proteins around NC_018145_3

CRISPR arrays

The CRISPR arrays of NC_018145_3

>merge|NC_018145|3|1756727-1757238|CRISPRCasFinder,CRT,PILER-CR
AGTACAACCTACCTATGCGGCAGTGAACGTAAAAGTCGGACAATACCTTCAGATCAATCATTTCTAAGCTGCCTGTGCGGCAGTGAACCAAGCTATAGCAAAATTGGAAAAGACAAATGCTTTCTAAGCTGCCTGTGCGGCAGTGAACATAAATATATCGGCATTCGCTGTCGGGCAGCTTTTCTAAGCTGCCTGTGCGGCAGTGAACTGCATCTTGATGTCGGAGCTGGTCTGATCGACTTTTCTAAGCTGCCTGTGCGACAGTGAACGACCCGTTCTGCGGCACCATGCCGAGAAGCTGTTTTCTAAGCTGCCTGTGCGGCAGTGAACGTGAGTCACTCGGTAAGAACCATTTTTTATCATTTCTAAGCTGCCTGTGCGGCAGTGAACGTAAATCAGCTGGAATTGTCGCTGACTGGATATTTCTAAGCTGCCTGTGCGGCAGTGAACATTACGCCGGTCTCCTGTCCAAAATTCGTAAGCCTTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NC_018145|3|3|1756727-1757238|CRISPRCasFinder
AGTACAACCTACCTATGCGGCAGTGAAC	GTAAAAGTCGGACAATACCTTCAGATCAATCA
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CAAGCTATAGCAAAATTGGAAAAGACAAATGC
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	ATAAATATATCGGCATTCGCTGTCGGGCAGCT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TGCATCTTGATGTCGGAGCTGGTCTGATCGACT
TTTCTAAGCTGCCTGTGCGACAGTGAAC	GACCCGTTCTGCGGCACCATGCCGAGAAGCTGT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	GTGAGTCACTCGGTAAGAACCATTTTTTATCA
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	GTAAATCAGCTGGAATTGTCGCTGACTGGATA
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	ATTACGCCGGTCTCCTGTCCAAAATTCGTAAGCC
TTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NC_018145|3|3|1756727-1757238|CRT
AGTACAACCTACCTATGCGGCAGTGAAC	GTAAAAGTCGGACAATACCTTCAGATCAATCA
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CAAGCTATAGCAAAATTGGAAAAGACAAATGC
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	ATAAATATATCGGCATTCGCTGTCGGGCAGCT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TGCATCTTGATGTCGGAGCTGGTCTGATCGACT
TTTCTAAGCTGCCTGTGCGACAGTGAAC	GACCCGTTCTGCGGCACCATGCCGAGAAGCTGT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	GTGAGTCACTCGGTAAGAACCATTTTTTATCA
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	GTAAATCAGCTGGAATTGTCGCTGACTGGATA
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	ATTACGCCGGTCTCCTGTCCAAAATTCGTAAGCC
TTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NC_018145|3|3|1756787-1757238|PILER-CR
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CAAGCTATAGCAAAATTGGAAAAGACAAATGC
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	ATAAATATATCGGCATTCGCTGTCGGGCAGCT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TGCATCTTGATGTCGGAGCTGGTCTGATCGACT
TTTCTAAGCTGCCTGTGCGACAGTGAAC	GACCCGTTCTGCGGCACCATGCCGAGAAGCTGT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	GTGAGTCACTCGGTAAGAACCATTTTTTATCA
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	GTAAATCAGCTGGAATTGTCGCTGACTGGATA
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	ATTACGCCGGTCTCCTGTCCAAAATTCGTAAGCC
TTTCTAAGCTGCCTGTGCGGCAGTGAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018145.1|WP_011241317.1|1763416_1763890_-|transcription-antitermination-factor-NusB	unknown	unknown	gnl|CDD|234686
NC_018145.1|WP_014849343.1|1751402_1752575_+|phosphotransferase	unknown	unknown	gnl|CDD|225213
NC_018145.1|WP_014849354.1|1763889_1765182_-|histidinol-dehydrogenase	unknown	unknown	gnl|CDD|234853
NC_018145.1|WP_014849341.1|1748016_1748808_+|pyruvate-formate-lyase-activating-protein	unknown	unknown	gnl|CDD|131546
NC_018145.1|WP_014849353.1|1762432_1763398_-|thiamine-phosphate-kinase	unknown	unknown	gnl|CDD|273589
NC_018145.1|WP_014849355.1|1765928_1766234_-|BolA-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376601
NC_018145.1|WP_011241331.1|1743523_1744954_-|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl|CDD|376587
NC_018145.1|WP_181406052.1|1745786_1748033_+|formate-C-acetyltransferase	unknown	unknown	gnl|CDD|153087
NC_018145.1|WP_014849349.1|1757712_1759239_-|amidophosphoribosyltransferase	unknown	unknown	gnl|CDD|236384
NC_018145.1|WP_014849351.1|1759661_1761050_-|glutamate--cysteine-ligase	unknown	unknown	gnl|CDD|130503
NC_018145.1|WP_181406051.1|1766596_1768759_-|squalene--hopene-cyclase	unknown	unknown	gnl|CDD|239222
NC_018145.1|WP_014849344.1|1752581_1752905_-|YnfA-family-protein	unknown	unknown	gnl|CDD|235016
NC_018145.1|WP_014849342.1|1748966_1751390_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|238657
NC_018145.1|WP_014849352.1|1761354_1762125_-|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl|CDD|236959
NC_018145.1|WP_014849348.1|1755702_1756407_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|212491
NC_018145.1|WP_011241312.1|1768789_1769356_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380063
NC_018145.1|WP_014849347.1|1755168_1755636_-|RNA-pyrophosphohydrolase	unknown	unknown	gnl|CDD|239643
NC_018145.1|WP_014849346.1|1754160_1755144_-|DUF481-domain-containing-protein	unknown	unknown	gnl|CDD|377313
NC_018145.1|WP_011241315.1|1765171_1765840_-|ATP-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234971
NC_018145.1|WP_014849345.1|1753369_1753936_+|nicotinamide-mononucleotide-transporter	unknown	unknown	gnl|CDD|377432

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018145.1|WP_011241317.1|1763416_1763890_-|transcription-antitermination-factor-NusB	gnl|CDD|234686	PRK00202, nusB, transcription antitermination factor NusB.	1.68678e-43
NC_018145.1|WP_014849343.1|1751402_1752575_+|phosphotransferase	gnl|CDD|225213	COG2334, COG2334, Putative homoserine kinase type II (protein kinase fold) [General function prediction only].	3.55892e-17
NC_018145.1|WP_014849354.1|1763889_1765182_-|histidinol-dehydrogenase	gnl|CDD|234853	PRK00877, hisD, bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Reviewed.	0
NC_018145.1|WP_014849341.1|1748016_1748808_+|pyruvate-formate-lyase-activating-protein	gnl|CDD|131546	TIGR02493, PFLA, pyruvate formate-lyase 1-activating enzyme. An iron-sulfur protein with a radical-SAM domain (pfam04055). A single glycine residue in EC 2.3.1.54, formate C-acetyltransferase (formate-pyruvate lyase), is oxidized to the corresponding radical by transfer of H from its CH2 to AdoMet with concomitant cleavage of the latter. The reaction requires Fe2+. The first stage is reduction of the AdoMet to give methionine and the 5'-deoxyadenosin-5-yl radical, which then abstracts a hydrogen radical from the glycine residue. [Energy metabolism, Anaerobic, Protein fate, Protein modification and repair].	7.77368e-142
NC_018145.1|WP_014849353.1|1762432_1763398_-|thiamine-phosphate-kinase	gnl|CDD|273589	TIGR01379, Thiamine-monophosphate_kinase, thiamine-phosphate kinase. This model describes thiamine-monophosphate kinase, an enzyme that converts thiamine monophosphate into thiamine pyrophosphate (TPP, coenzyme B1), an enzyme cofactor. Thiamine monophosphate may be derived from de novo synthesis or from unphosphorylated thiamine, known as vitamin B1. Proteins scoring between the trusted and noise cutoff for this model include short forms from the Thermoplasmas (which lack the N-terminal region) and a highly derived form from Campylobacter jejuni. Eukaryotes lack this enzyme, and add pyrophosphate from ATP to unphosphorylated thiamine in a single step. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	3.5393e-120
NC_018145.1|WP_014849355.1|1765928_1766234_-|BolA-family-transcriptional-regulator	gnl|CDD|376601	pfam01722, BolA, BolA-like protein. This family consist of the morphoprotein BolA from E. coli and its various homologs. In E. coli over expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division. The expression of BolA is growth rate regulated and is induced during the transition into the the stationary phase. BolA is also induced by stress during early stages of growth and may have a general role in stress response. It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5.	1.25422e-27
NC_018145.1|WP_011241331.1|1743523_1744954_-|cytochrome-ubiquinol-oxidase-subunit-I	gnl|CDD|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	0
NC_018145.1|WP_181406052.1|1745786_1748033_+|formate-C-acetyltransferase	gnl|CDD|153087	cd01678, PFL1, Pyruvate formate lyase 1. Pyruvate formate lyase catalyzes a key step in anaerobic glycolysis, the conversion of pyruvate and CoenzymeA to formate and acetylCoA. The PFL mechanism involves an unusual radical cleavage of pyruvate in which two cysteines and one glycine form radicals that are required for catalysis. PFL has a ten-stranded alpha/beta barrel domain that is structurally similar to those of all three ribonucleotide reductase (RNR) classes as well as benzylsuccinate synthase and B12-independent glycerol dehydratase.	0
NC_018145.1|WP_014849349.1|1757712_1759239_-|amidophosphoribosyltransferase	gnl|CDD|236384	PRK09123, PRK09123, amidophosphoribosyltransferase; Provisional.	0
NC_018145.1|WP_014849351.1|1759661_1761050_-|glutamate--cysteine-ligase	gnl|CDD|130503	TIGR01436, Glutamate--cysteine_ligase_chloroplastic, glutamate--cysteine ligase, plant type. This model represents one of two highly dissimilar forms of glutamate--cysteine ligase (gamma-glutamylcysteine synthetase), an enzyme of glutathione biosynthesis. The other type is modeled by TIGR01434. This type is found in plants (with a probable transit peptide), root nodule and other bacteria, but not E. coli and closely related species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs].	0
NC_018145.1|WP_181406051.1|1766596_1768759_-|squalene--hopene-cyclase	gnl|CDD|239222	cd02892, SQCY_1, Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization cascade converting linear triterpenes to fused ring compounds. This group contains bacterial SQCY which catalyzes the convertion of squalene to hopene or diplopterol and eukaryotic OSQCY which transforms the 2,3-epoxide of squalene to compounds such as, lanosterol in mammals and fungi or, cycloartenol in plants. Deletion of a single glycine residue of Alicyclobacillus acidocaldarius SQCY alters its substrate specificity into that of eukaryotic OSQCY. Both enzymes have a second minor domain, which forms an alpha-alpha barrel that is inserted into the major domain.	0
NC_018145.1|WP_014849344.1|1752581_1752905_-|YnfA-family-protein	gnl|CDD|235016	PRK02237, PRK02237, YnfA family protein.	3.33285e-38
NC_018145.1|WP_014849342.1|1748966_1751390_+|TonB-dependent-receptor	gnl|CDD|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	5.77448e-38
NC_018145.1|WP_014849352.1|1761354_1762125_-|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl|CDD|236959	PRK11713, PRK11713, 16S ribosomal RNA methyltransferase RsmE; Provisional.	1.47614e-74
NC_018145.1|WP_014849348.1|1755702_1756407_-|SDR-family-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	3.20315e-29
NC_018145.1|WP_011241312.1|1768789_1769356_-|TetR-family-transcriptional-regulator	gnl|CDD|380063	pfam17937, TetR_C_28, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in CgmR (C. glutamicum multidrug-responsive transcriptional repressor), previously called CGL2612 protein. CgmR (CGL2612) from Corynebacterium glutamicum is a multidrug-resistance-related transcription factor belonging to the TetR family. It regulates expression of the immediately upstream gene cgmA (cgl2611) by binding to the operator cgmO in the cgmA promoter. The cgmA gene encodes a permease belonging to the major facilitator superfamily, a protein family composed of bacterial multidrug exporters, and the pair of CgmR and CgmA confers multidrug resistance on C. glutamicum.	1.92303e-12
NC_018145.1|WP_014849347.1|1755168_1755636_-|RNA-pyrophosphohydrolase	gnl|CDD|239643	cd03671, Ap4A_hydrolase_plant_like, Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant enzymes fall into one group (represented by this subfamily) and fungi/animals/archaea enzymes fall into another. Bacterial enzymes are found in both subfamilies. Ap4A is a potential by-product of aminoacyl tRNA synthesis, and accumulation of Ap4A has been implicated in a range of biological events, such as DNA replication, cellular differentiation, heat shock, metabolic stress, and apoptosis. Ap4A hydrolase cleaves Ap4A asymmetrically into ATP and AMP. It is important in the invasive properties of bacteria and thus presents a potential target for the inhibition of such invasive bacteria. Besides the signature nudix motif (G[X5]E[X7]REUXEEXGU where U is Ile, Leu, or Val), Ap4A hydrolase is structurally similar to the other members of the nudix superfamily with some degree of variations. Several regions in the sequences are poorly defined and substrate and metal binding sites are only predicted based on kinetic studies.	9.50921e-74
NC_018145.1|WP_014849346.1|1754160_1755144_-|DUF481-domain-containing-protein	gnl|CDD|377313	pfam04338, DUF481, Protein of unknown function, DUF481. This family includes several proteins of uncharacterized function.	1.39052e-57
NC_018145.1|WP_011241315.1|1765171_1765840_-|ATP-phosphoribosyltransferase	gnl|CDD|234971	PRK01686, hisG, ATP phosphoribosyltransferase catalytic subunit; Reviewed.	1.37428e-112
NC_018145.1|WP_014849345.1|1753369_1753936_+|nicotinamide-mononucleotide-transporter	gnl|CDD|377432	pfam04973, NMN_transporter, Nicotinamide mononucleotide transporter. Members of this family are integral membrane proteins that are involved in transport of nicotinamide mononucleotide.	5.36745e-43

Protein sequences

>NC_018145.1|WP_014849348.1|1755702_1756407_-|SDR-family-oxidoreductase
MTHRPLSDQIALVTGASRGIGAATAKALAEAGAHVILVARTATDLDKVEEQIYQKGGSATIAPLDITHSGSCHHLAAAISGRWPALDIMVFAAARYEAQPSIAAASPALQQMLAVNALATQDLLSRFDPLIQESRSAHIVGLTLPKSQAPYPYNGSYYASKMAMEAILLSYGAENAKRDTIKVALAELEAVATEGRKRAFPDEKADLLRSPDEVAKAIVTMIVQDYANGWQGKL
>NC_018145.1|WP_014849347.1|1755168_1755636_-|RNA-pyrophosphohydrolase
MDNLEYRSGVGIMLLNKDNLVFAACRNDMKEEAWQMPQGGLEAKETPEVGVLRELEEETGIPPRMVAIISHTKEWLTYDFPADLQASFFKNKYRGQRQLWFLARYLGRDEDININTDKPEFRAWKWVEPKQLPNLIVAFKKPLYEKILSEFSASL
>NC_018145.1|WP_014849346.1|1754160_1755144_-|DUF481-domain-containing-protein
MQSRTISPWLLWRISQGAVLLSLVPVSEVWAEEPPKLIQEMITKALALDDPKTVKSIVLIAKKTVPDSAAEIDAMVADYNTKVEAKEAEKKRKELRRVADSGMFENWTGSVELGGAKMTGNTRQTAIYGAVALERNGINWTHTIKARTDFQRTYGTTSAERFTASYQPHYKFDERLYLYGLALYERDMFLGYRTRITGGSGIGYKVFDQPNLSLAVEGGPAYRHTIFIDSSRPNGRWIRDTAAMRGSFTTKWVVSPLLTVSEDSSIFFESKDITASSTTSLETKLIGNLSTKLSFSVYYEKDVSASKNPVDTTSRITFAYALGKKKK
>NC_018145.1|WP_014849345.1|1753369_1753936_+|nicotinamide-mononucleotide-transporter
MSVLEWLAVLTSLLGIIFSTRQIRICWLFYGISSLLYGKIFFSIKLYADCLLQIFFFFSSIYGWFHWHHYQKADKMTVITASHKSLLRDIAMAAALSAIFGFYLKNYTDDAFPWLDAILSCYSIVAQFWAARLYKANWFLWIVIDFCYTALFCYRGLWLTAWLYSVFMVMAVIGLKKWQNKNPAVACD
>NC_018145.1|WP_014849344.1|1752581_1752905_-|YnfA-family-protein
MLALLYIPAALAEITGCFSFWAWIRLHKSPLWLLPGIASLLLFAWLLTFSPAENAGKAYAIYGGIYIIMSLLWSWKVEATPPDHWDLIGAAFCLVGAAIILWMPRSL
>NC_018145.1|WP_014849343.1|1751402_1752575_+|phosphotransferase
MAIKDDGMTEAAHKAVHQFGVSGYQTERDWPYLTILEINAVLASFRGQGKAIKILSHSRRPYSAAALFETDQKQTFFIKRHHHKIRNKTEILKEHLFARHLAQKSFPISTPMMADHNQTVIEKEPWIYEIHPQAQGVDIYQDVMSWEPFLNRDHAYEAGRMLALFHQAAQGFDQSPRHHALLVSAGDVLLHDNFIKALSEWITAQPELLKQLETKNWRQDIIENILPFHHQLQPLIADITPLWGHGDWHSSNLMWTGRDPKAKVSYVLDLGMADYTSAMFDLATAIERNVIAWLDMDSHQDIVIYDQLFALLRGYHHIKPLSQIDKQLLSAFMPLLHVEYALSEMVYFGALLQDKTSADIAYYDYLLGHSRWFSEQEGQRLLQKIIHFEA
>NC_018145.1|WP_014849342.1|1748966_1751390_+|TonB-dependent-receptor
MTYQDMTASEWRKYYQHFLVTSVFLAGISGVFPIHPAHAETQEAPKSSDKTPSKSDAIIVTGRPVFKTANGFSVNDIGGGLIQKETETRSVSHISTDFIQKQAPTANAFDLVAMLPGANVTSSDPLGFSTQTNITIRGLSGDAIGYVLEGMPLNDVAYYTGYPTQFADSENYQQIGLAQGSADLDSPVLNAAGGVMNLNFRKPADKMGGYADFSYGSYNTNRQFLRFDMGEIGHSGVKGFVSYSHARTDNWRGAGYDEKQHVDFKFLKEWGQDSHVSLLGTWNKGITSYYPQVDKQSWKENGISGSNNLASRYNVNNDAAGTDYWRLYRAPEEIFYLAAPIDVRLASNLKLKVTPYGQWDRGNVPAGSTLNNSGLWNGSEAIAGTINLPNATDGTATVRSNYTQRSARAGVNASATWSLKNHDLTLGYWFDYSADEEQNSFTPVDSNGYASNLWADRHSTLIKMPDGSPLLGTNNRTHTYVNAVYLGDHMTFLQNRLTFDIGFKEVIMTRHGYNYLPGSQHKANFSTSEPLPRLGLRYQIDSKSHVFFSASTNFRTADETALYNSYDPTSGDIIVNGNKNLKNEYSVSEELGYRYSDALVTGSLTLFNYNFSNRQLQTVIVQNGSHIQSTINAGNQISRGVDFEVGLAPWHHISPYLSGEYLYTRQTSDLTVGDDLLPTKGKRAVRSPAFQGSLGVTYDDHHFFGMASVKYTGSQYGSFMNDEKIPAYVTGNISVGYRFTQEAFLKHPEIRLNFINIGNNHYLSGIASPTANAQDTVGRNGTVISGSAPQYYIGGGFAVLASLSSAF
>NC_018145.1|WP_014849341.1|1748016_1748808_+|pyruvate-formate-lyase-activating-protein
MALIIKRPAVTSLVEEAGCDNTLKGRIHSTEIGGAVDGPGVRFVLFLAGCALRCQYCHNPDSWFLKNGRAVTLAEMMEEVASYADFLKRAGGGITISGGEPLVQPEFTGALLKAAQYLGLHTAIDTAGFLGAQADDALLSNTDLVLLDIKAFNDKRYKALTGVELQPTLAFAKRLAALKKTVWLRYVLVPGLTDNFNEIANLADFAATLGNIERVDVLPFHKMGEYKWKASGLAYKLGDTQPPSPALVEDVRGIFRDNGLNLS
>NC_018145.1|WP_181406052.1|1745786_1748033_+|formate-C-acetyltransferase
MDSALDPWRGFKGRKWQREIDTRDFILSNVTSYTGNSDFLAGITPKTTKLWEKLQVSLEAERKTQGGVLDVDTSTVSNITAHAPGFIEKDLEVVVGLQTDAPLKRAIMPFGGYRMIKKGLEAYGFKEDESLSKIFPALRKTHNDGVFDVYTPEIMACRRSGIITGLPDAYGRGRIIGDYRRVALYGVDCLIEDKKEQGKRLERNPFDEETIKLREEVAEQIKALHELAAMAKSYGYDISQPAVTAQQAVQWTYFAYLAAVKEANGAAMSLGRVSTFLDIYIERDLKEGRITEAEAQELVDQFVMKLRIVRFLRTPEYDQLFSGDPTWVTESLGGMAIDGRTLVTKSSFRFLHTLENLGPAPEPNLTVLWSENLPKGFKDYCAKISIDTSSIQYENDDLMRSYWGDDYGIACCVSAMRIGKQMQFFGARANLAKTLLYAINGGRDEKSGVQVAPAFAPVTGDILDYEDVKSRMVQMMEWLASVYINALNAIHFMHDKYMYERVEMALHDLEILRTMACGIAGLSVAADSLSAIKYAKVKIIRDERGLATDFEIEGDYPAYGNNDDRADEIAIWLVETFMNMLRKQTTYRRSVPTQSILTITSNVVYGKKTGNTPDGRRAGEPFAPGANPMHGRDLKGPVASMASVAKLPYAHAQDGISNTFTIVPNALGMNKEERIDNLIGLLSGYFGAGAHHMNVNVFDRNTLLDAVDHPEKYPQLTIRVSGYAVNFVKLTREQQMDVIHRTFHGLDN
>NC_018145.1|WP_011241331.1|1743523_1744954_-|cytochrome-ubiquinol-oxidase-subunit-I
MVPDATALMLARIQFAFTVGFHIIFPAFSIGLAAYLAVLEGLWLKTGRNVYLHLFKYWIKIFALVFGMGVVSGLVMAYEFGTNWSLFSQKAGAITGPLLGYEVLTAFFLEAGFLGIMLFGLGRVGKGLHFLATCLVSIGTLISMTWILASNSWMQTPAGYSIDPKTGHFLPKSWFEVIFNPSFPYRLVHMGMAAFICVAFVVGATAAFHMLRDRKNGKPVTEPVRVMFSMALWMAAIAAPFQLLAGDMHGLNTLKYQPAKIAAMEGDWESEGPASEILFGIPNMKTERTDYAIKIPYAGSLILTHSLNGKVPGLKDYPRDQRPPSPILFFSFRIMVGLGGLMILLGLWSLFLRFRGQLYNNKALQWATLLMAPSGFIALLCGWVTTEVGRQPYTVYGLLRTSDSVSPVMLPSMIFSMTAFVIVYFFVFGAGMLILFRMLSHQPSSHEKGADPENPLQNSHAKGATQLAQDLSGKRS
>NC_018145.1|WP_014849349.1|1757712_1759239_-|amidophosphoribosyltransferase
MSPSLSSELFSDSISTLTTTTESLDNGASDDTLHEECGVFGIWGADTAAAVVALGLHALQHRGQEAAGITSWDGKNFHSRRAVGHVAGNFDRDDAIRSLPGSCAIGHVRYATTGASTLCNVQPLYAELVSGGFAIAHNGNISNAETLRHQLVRHGSIFQSTSDTETIIHLVATSSYRSLLDRFIDALKQVEGAYSLVCLTPEGMIACRDPLGIRPLVLGKVGETFVVASETVALDIIGGTYIRQVEPGELIIISEKGLQSLHPFKKQKPRPCIFEHVYFSRPDSLIGSTSVYSVRKSIGIELARENPVEADMVIPVPDSGTPAAIGYAQQSSLPFELGIIRSHYVGRTFIQPGDQVRHLGVKLKHNANRALINGKKLVLVDDSIVRGTTSVKIIRMLRDAGAKEIHLRIASPPTRHSCFYGVDTPERAKLLAAKMTVEQMAEYIGADSLAFISMDGLYRAVGEEGRNDAQPQYCDACFTGAYPTPLTDLGELSASEQLVRLSEQVAIA
>NC_018145.1|WP_014849351.1|1759661_1761050_-|glutamate--cysteine-ligase
MSTRQTSSSQNHPIESRDDLLRIFQAGEKPKAQWRVGTEHEKLVYKKQNHQAPSYEEKGGICELLQGFTRFGWQPIYENDKIIGLSGDDGAISLEPAGQFELSGAPRSTIHESYDEICRHIQQTQEVGDELGLGFLGLGLWPDKKRSDLPLMPKGRYKIMTEYMPKVGKLGLDMMLRTCTIQSNIDYGSEADMVKKFRVSLALQPLATALFANSPFLEGRPNGFSSYRSHIWTDTDPHRTGILPFVFDDDFGYERYIDYMLSVPMYFVYRDGRYINASGQDFRAFLRGELPALPNEKPILSDWVDHLSTAFPEVRLKSYLEMRGADGASAMMSPALSAFWISILYDSELLDIASDIIKSWSMDDYRNLRNEVPKKGLKTLIGGRQSLLDLGRQLWPLMNDALKRRAILNDKGQDESRYLAPIGEILESGQSLSDRLLARYHQTGNLDFIYQECDWAQPHILS
>NC_018145.1|WP_014849352.1|1761354_1762125_-|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MVAEPAWPVNTLPRLYVEEKLSLEAVIIPERAQAHYLLSVMRFKMGSQLVLFDNLTGEWLGEVIEAGRKHLQLKITHHLNEKESIPDLWLLTAPIKKGRIDWIYEKACELGVARIMPVITQRTIVDRVNLERLQAHIVEAAEQCGRTSLSEVTEPRSLKSLLAEWPEDRALFFADETGGEPMIEALSKRKMAAAILVGPEGGFTDQERDMINAVKQAVPVSLGPRILRADTAAIAATALWMAAAGDWQKQPRQANL
>NC_018145.1|WP_014849353.1|1762432_1763398_-|thiamine-phosphate-kinase
MSAREQAFITALRQIAGDPAARNLSDDAAVLPRPSGDLVLSHDIIVENVHYFPSDPPETVAQKLVGVNLSDLAAKGAKPIGALMGYSLGPDYKWDQAFLKGLESVCHQYNLPLLGGDTVAVPRHTGHFSAMTVIGLAPSCGVPDRRAAKEGDELWVTSPIGDAGFGLNLLKQKKDINHSAQEKLVQAYRSPEPRLKEGIWLAPHVHAMADISDGLLIDAERIANASGLAVRIRLDRVPLSSEAISCFGDTKSTRLQAVTAGDDYQLIMACAPNKRQELLKLSKEKQFDLYRVGQLTAGSGLSLFYGAEPIKQPDRLGYLHG
>NC_018145.1|WP_011241317.1|1763416_1763890_-|transcription-antitermination-factor-NusB
MAQTQKRPHKNARSAARLAAVQALYQREMEKTPLNILLDEFHQYRLGATIEDATYTKAEPSFFDDIVRGVGTRCEEIDRVISENLSERWSLDRLDRPMRQILRAGTYELLARPDVPTATVISEYIDVANAFYDRQEKNFVNGLLDTVAKKLRSSNNA
>NC_018145.1|WP_014849354.1|1763889_1765182_-|histidinol-dehydrogenase
MLLKLDSRKADFEAGFTRLVDERRESEGDVSRDVSAIIADVKKRGDVAIAELTQKFDRHDLNKGGWQLTQEEIKKACDSLPSELMDALKLAATRIRYCHENQLPESSEMTDAAGVRMGVRWQAVEAAGLYVPGGRAAYCSSVLMNAVPAKVAGVKRLVMVTPTPDGFVNPAVIAAAVISEVDEIWKIGGAQAVAALALGTEKIKPVDVVVGPGNAWVAEAKRQLYGQVGIDMVAGPSEIVVVADKDNDPEWLAADLLSQAEHDPTSQSILISDSEDLIEKTIEAVGRRLEKLETQKVARESWDKHGATILVQSLDEAPALVDRLAPEHLELAVADPDALFANVHHSGSVFLGRYTPEAIGDYVGGPNHVLPTGRRARFSSGLSVIDFMKRTTYLNCSQEALSKIGPAAVTLAKAEGLPAHAESVISRLNK
>NC_018145.1|WP_011241315.1|1765171_1765840_-|ATP-phosphoribosyltransferase
MTKPLVFAIPKGRILKEALPMLEAAGIIPEPAFLDKESRLLRFKTNRPDIEIIRVRAFDVATFVAHGAAQMGIVGSDVIEEFSYPELYAPVDLDIGHCRLSIAEPKRLAKDDDPREWSHVRVATKYPHLTHRHFEARGVQAECIKLNGAMEIAPALGLAGRIVDLVSSGRTLEENGLVEVEKIMPISARLIVNRAAFKMRAGDIAPLVENFRRLVGVADNVA
>NC_018145.1|WP_014849355.1|1765928_1766234_-|BolA-family-transcriptional-regulator
MNMSSPSDNNEGPVARLMRERLEAAFSPETLVIEDDSNKHAGHAGHPHRSESHFTVTLVSQAFENESRINRERRVHKALSDLLPDRIHALRLKLSTPLRQE
>NC_018145.1|WP_181406051.1|1766596_1768759_-|squalene--hopene-cyclase
MNSLSRLLMKKIFGAEKTSYKPASDTIIGTDALKRPNRRPEPTAKVDKTIFKTMGNSLNNTLVSACDWLIGQQKPDGHWVGAVESNASMEAEWCLALWFLGLEDHPLRPRLGNALLEMQREDGSWGVYFGAGNGDINATVEAYAALRSLGYSADNPVLKKAAAWIAEKGGLKNIRVFTRYWLALIGEWPWEKTPNLPPEIIWFPDNFVFSIYNFAQWARATMVPIAILSARRPSRPLRPQDRLDALFPEGRARFDYELPKKEGINLWSQFFRTTDRGLHWVQSNLLKRNSLREAAIRHVLEWIIRHQDADGGWGGIQPPWVYGLMALHGEGYQLYHPVMAKALSALDDPGWRHDRGESSWIQATNSPVWDTMLALMALKDAKAEDRFTPEMDKAADWLLARQVKVKGDWSIKLPDVEPGGWAFEYANDRYPDTDDTAVALIALSSYRDKEEWQKKGVEDAITRGVNWLIAMQSECGGWGAFDKDNNRSILSKIPFCDFGESIDPPSVDVTAHVLEAFGTLGLSRDMPVIQKAIDYVRSEQEAEGAWFGRWGVNYIYGTGAVLPALAAIGEDMTQPYITKACDWLVAHQQEDGGWGESCSSYMEIDSIGKGPTTPSQTAWALMGLIAANRPEDYEAIAKGCHYLIDRQEKDGSWKEEEFTGTGFPGYGVGQTIKLDDPALSKRLLQGAELSRAFMLRYDFYRQFFPIMALSRAERLIDLNN
>NC_018145.1|WP_011241312.1|1768789_1769356_-|TetR-family-transcriptional-regulator
MARPRTIDRERVLKSAEQLVQRAGATAMTLEAVAKEAGITKGGLQYCFGSKDDLITALIDRWFAAFDCEVKEYSQSDDSPAGEARAYVQASSQIDDATSARMVGMLVTLLQSPNHLKKIQAWYARWMEKNLGQSEEARHIRTMLFAAEGAFFLRSLGFIKMSESEWATVFDDIKKLVPSAQAGRASFK

Crispr_ID: NC_018145_4

• CRISPR_ID: NC_018145_4
• CRISPR_location: 1793736-1793801
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_018145_4

Consensus_repeat	Method
TCTCTTTCTGCGCCCGAAGTTGG	CRISPRCasFinder

spacers of NC_018145_4

>4.1|1793759|19|NC_018145|CRISPRCasFinder
AAATATCGCGAAATCTTCT

CRISPR arrays and Neighbor proteins around NC_018145_4

CRISPR arrays

The CRISPR arrays of NC_018145_4

>merge|NC_018145|4|1793736-1793801|CRISPRCasFinder
TCTCTTTCCGTATCGGAAGTCGGAAATATCGCGAAATCTTCTTCTCTTCCTTCGTCCAAAGTTGGA

>NC_018145|4|4|1793736-1793801|CRISPRCasFinder
TCTCTTTCCGTATCGGAAGTCGG	AAATATCGCGAAATCTTCT
TCTCTTCCTTCGTCCAAAGTTGGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018145.1|WP_014849365.1|1789510_1792810_+|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|182589
NC_018145.1|WP_011241288.1|1804259_1804637_+|50S-ribosomal-protein-L20	unknown	unknown	gnl|CDD|179959
NC_018145.1|WP_011241291.1|1802136_1803072_+|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl|CDD|234929
NC_018145.1|WP_014849363.1|1782517_1783183_-|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl|CDD|235140
NC_018145.1|WP_011241300.1|1783588_1784599_-|KpsF/GutQ-family-sugar-phosphate-isomerase	unknown	unknown	gnl|CDD|182814
NC_018145.1|WP_014849374.1|1806022_1808392_+|phenylalanine--tRNA-ligase-subunit-beta	unknown	unknown	gnl|CDD|234804
NC_018145.1|WP_014849372.1|1803117_1803897_+|inositol-monophosphatase-family-protein	unknown	unknown	gnl|CDD|238819
NC_018145.1|WP_041573222.1|1804925_1806026_+|phenylalanine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl|CDD|234780
NC_018145.1|WP_014849361.1|1776320_1779845_+|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl|CDD|235554
NC_018145.1|WP_014849360.1|1775665_1775968_-|ferrous-iron-transport-protein-A	unknown	unknown	gnl|CDD|377199
NC_018145.1|WP_141914866.1|1780210_1780968_+|IS5-family-transposase	unknown	unknown	gnl|CDD|379129
NC_018145.1|WP_014849369.1|1797447_1800468_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|238657
NC_018145.1|WP_011241289.1|1804042_1804246_+|50S-ribosomal-protein-L35	unknown	unknown	gnl|CDD|234676
NC_018145.1|WP_014849364.1|1786415_1789514_+|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|182501
NC_018145.1|WP_014849371.1|1801701_1801932_+|DUF2093-domain-containing-protein	unknown	unknown	gnl|CDD|226423
NC_018145.1|WP_014849362.1|1781492_1782041_-|DUF308-domain-containing-protein	unknown	unknown	gnl|CDD|225786
NC_018145.1|WP_011241299.1|1785053_1786376_+|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|183194
NC_018145.1|WP_011241301.1|1783182_1783416_-|phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl|CDD|376904
NC_018145.1|WP_014849370.1|1800974_1801553_+|hypothetical-protein	unknown	unknown	unknown
NC_018145.1|WP_014849368.1|1796061_1796991_-|DMT-family-transporter	unknown	unknown	gnl|CDD|223769

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018145.1|WP_014849365.1|1789510_1792810_+|efflux-RND-transporter-permease-subunit	gnl|CDD|182589	PRK10614, PRK10614, multidrug efflux system subunit MdtC; Provisional.	0
NC_018145.1|WP_011241288.1|1804259_1804637_+|50S-ribosomal-protein-L20	gnl|CDD|179959	PRK05185, rplT, 50S ribosomal protein L20; Provisional.	3.98401e-62
NC_018145.1|WP_011241291.1|1802136_1803072_+|ribose-phosphate-pyrophosphokinase	gnl|CDD|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NC_018145.1|WP_014849363.1|1782517_1783183_-|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl|CDD|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	2.56052e-141
NC_018145.1|WP_011241300.1|1783588_1784599_-|KpsF/GutQ-family-sugar-phosphate-isomerase	gnl|CDD|182814	PRK10892, PRK10892, arabinose-5-phosphate isomerase KdsD.	1.42528e-87
NC_018145.1|WP_014849374.1|1806022_1808392_+|phenylalanine--tRNA-ligase-subunit-beta	gnl|CDD|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	0
NC_018145.1|WP_014849372.1|1803117_1803897_+|inositol-monophosphatase-family-protein	gnl|CDD|238819	cd01641, Bacterial_IMPase_like_1, Predominantly bacterial family of Mg++ dependend phosphatases, related to inositol monophosphatases. These enzymes may dephosphorylate fructose-1,6-bisphosphate, inositol monophospate, 3'-phosphoadenosine-5'-phosphate, or similar substrates.	4.43616e-113
NC_018145.1|WP_041573222.1|1804925_1806026_+|phenylalanine--tRNA-ligase-subunit-alpha	gnl|CDD|234780	PRK00488, pheS, phenylalanyl-tRNA synthetase subunit alpha; Validated.	0
NC_018145.1|WP_014849361.1|1776320_1779845_+|DNA-polymerase-III-subunit-alpha	gnl|CDD|235554	PRK05673, dnaE, DNA polymerase III subunit alpha; Validated.	0
NC_018145.1|WP_014849360.1|1775665_1775968_-|ferrous-iron-transport-protein-A	gnl|CDD|377199	pfam04023, FeoA, FeoA domain. This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.	8.63252e-16
NC_018145.1|WP_141914866.1|1780210_1780968_+|IS5-family-transposase	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.56061e-22
NC_018145.1|WP_014849369.1|1797447_1800468_-|TonB-dependent-receptor	gnl|CDD|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	1.02111e-28
NC_018145.1|WP_011241289.1|1804042_1804246_+|50S-ribosomal-protein-L35	gnl|CDD|234676	PRK00172, rpmI, 50S ribosomal protein L35; Reviewed.	9.09166e-21
NC_018145.1|WP_014849364.1|1786415_1789514_+|efflux-RND-transporter-permease-subunit	gnl|CDD|182501	PRK10503, PRK10503, MdtB/MuxB family multidrug efflux RND transporter permease subunit.	0
NC_018145.1|WP_014849371.1|1801701_1801932_+|DUF2093-domain-containing-protein	gnl|CDD|226423	COG3908, COG3908, Uncharacterized protein conserved in bacteria [Function unknown].	4.11974e-21
NC_018145.1|WP_014849362.1|1781492_1782041_-|DUF308-domain-containing-protein	gnl|CDD|225786	COG3247, HdeD, Uncharacterized conserved protein [Function unknown].	1.10757e-14
NC_018145.1|WP_011241299.1|1785053_1786376_+|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl|CDD|183194	PRK11556, PRK11556, MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit.	9.6446e-106
NC_018145.1|WP_011241301.1|1783182_1783416_-|phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl|CDD|376904	pfam02700, PurS, Phosphoribosylformylglycinamidine (FGAM) synthase. This family forms a component of the de novo purine biosynthesis pathway.	5.97042e-35
NC_018145.1|WP_014849368.1|1796061_1796991_-|DMT-family-transporter	gnl|CDD|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.49223e-12

Protein sequences

>NC_018145.1|WP_014849365.1|1789510_1792810_+|efflux-RND-transporter-permease-subunit
MNLSRPFISRPIGTTLLTIGIALAGIIAYFKLPVAPLPQIDFPVIVVQASMAGASPDTMANSIAQPLERRLGVIADVTEMTSTSSVGSTQIALEFGLDRDINGAAREVQAAISAARADLPSTLQSNPSYLKVNPSMMPVMVLALTSDSKTPGQIYETVSNLVSQRLSQVSGVGEVEIGGGSLPGVRIDVSPYALSRFGLSLEDVRATIESANANRPKGALESPDGHHFQIYTNQLGRDAKLYGDLVVAWRDGTTAIRLKDIASVTDGVADTRNLGLFNGHPAVIVLITQQPGANLINLVDSLRAELPHLEKMLPSDVHVTVANDRTSSIRSTLNEVRLTLIISLILVIAVVGVFLRNLSAVVIPAVAASVSLLGTFAVMYFAGFSLNNLSMMAIIVATGFVIDDAIVVLENIARHLENGMGRMEAALLGAQEVGFTVLSISLSLVAVFIPLLFLGGIGGRLFREFAVSLSAAVLISMVISLTTTPMMCAWMLSPRKEDKKQGRIADFFEKSFAHVEKAYSYALNWALSMKPLMLVLFLLVLVLTVYLYAVVPKSFFPQQDSPILMAGVRADRSSSFQTMEKKLTKTVNILRQEKQVSTVIGFTGGKRSGSAFLMVELKPWGERKEKATTVINRLRPKLAQLTGISVFLSPMQDLRMGARSSDATYQYTLISDDSKALQDWVPKLTQALQTSNILTDVDNDLALNGIESMVNIDRDSASRLGISARNVDNALYDSFGQRQIATIYEDINQYPVVFEWTPKDQQGPQALQNLYIPENSSTNSASSTNTTAIAGTGTNAAGATSVANDSSALSVNSTGSGNSGDANSANPSLRDPSTGSALNTSASTMVPLPAIAKFSLHATDLSIQHDNGEAAATISFNLKSGHNLNEAQSEIKAKMAQLMVPANIRGNFAGTAKLGNDSGSQALLLLAALITIYIVLGILYENLIHPITVISTLPAAGVGAVLALMIIHMDFSLIALIGVFLLMGIVKKNAILVIDVALHLQREQGLSAEEAMRQSCVLRFRPIIMTTLAAALGVVPLAIGFGEGSEFRQPLGVTIIGGLVVSQMLTLFTTPVIYIYFDRLSRWRPWRRKAKAENRLEKA
>NC_018145.1|WP_014849364.1|1786415_1789514_+|efflux-RND-transporter-permease-subunit
MNPSRLFILRPVATSLIVIAIVLAGLLGFHYMSLSALPEVDYPTIQVSTLYPGASPEVISQTVSAPLERQFGQMSGLSRMTTKSAAGASVITLQFGLNEALDVAEQEVQAAINAANALLPADLPAPPVYAKVNPADSPVLTLAATSDTMPLTDVQNLVQTRLAQKISQVSGVGLVELSGGQRPAMRIQADTQALASYGISLSTLRTAIDNANANSAKGSFDGPTRSWQINANDQLLTVEDYKNLIIAMRNSRPVRMSDVAQVVAGAENNHLGAYYNITPAVIINVRRQPGANVIATVDNIKKQLPELEAGLPAGLKISVVADRTTGIRASIEHVEVELVLAVVMVILVIFFFLHSIRATLIAAVAVPISLIGSFAAMYMMNYSLNNLSLMALTIASGFVVDDAIVMIENIERHIEAGVAPFQAALKGAQEIGFTIISLTISLIAVLIPLLFMSDVVGRLFREFAMTLAITILISAVVSLTLTPMLSARLLVAHRHKNPIGDRIQKGFERLEYHYEHGLRWVLGHQTLTLVLTIVTFIGTALFYVAIPKGLFPLQATGQLRIQTDTSPDVSYSRMAELQKQAAAKILQDPAVENLSVMSGVDGVTNSALNQGVMLVNLKEGISDEQPVIKRLYQAVGAVAGIRAHIQPVQDLTVDTDTGPTRFRLSVEGADTDSVHKAARAIADSLGQSKKLTDVYTDADAKGDAVYVNIDRETASRLSVTVADIDDTLYSAFGQRIISTIFTETNQYRVILEARPNLLNSIESLGHLNLAGSGTLPTPLNGFSTLKIGQAPLQIMHVAQFPAATVGFDLASNTALGDGVKAVRAQIARLDLPSGITTTLLGAASAYEKALGNQILLIFAALVCVYIVLGVLYESYIHPLTILSTLPSASVGAILALWVSGHDLDIIGIIGIILLIGIVKKNAIMMIDFAIAAEREEKKSPEEAIFNAATLRFRPILMTTLAALFAAIPLMIGHGSGAELRRPLGLAIFGGLLASQMLTVFTTPVIYLFFDRLGQKIAYLRRHKDSENEVKSA
>NC_018145.1|WP_011241299.1|1785053_1786376_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MQEETDGQNMPHPDKKQETIEPSSAPSLSKKGKLKSWIISLIVLALIFLLIAYITHNNKANTQKSASHGHHGKSSKMGPPGDDGDMPVTVSIVKSKTADVPIVVEALGTVTPVSTITVKPQVSGYIKRILYTEGQMVKEGQPLALIDPRLYSAQLVQNEGALRRDIAQLENARIQLARDRQLGSDSIAKQDVDTQAATVHQLEGTVEADRGAVEYSKVNLGYTTIPSPVTGRVGLRPIDQGNYIAAGDSSGVAVVTSLDPIDVVFTMAQDFVPEVEKQVRTGRQLTGTAYDRTKTENLGEGWLLTLDNRIDTTSGTVKGKIRFHNATGKLFPNQFVNIHLNVETLRQVVTVPSTAIREADNGSYVWLVDKQRKVHRHFVTTGNSYGDNIVILKGLDANQLVVTEGGDRLIENSEVQTPAESSKEMNIKPRDNATKTQAKS
>NC_018145.1|WP_011241300.1|1783588_1784599_-|KpsF/GutQ-family-sugar-phosphate-isomerase
MQQSLQTVDDSTPYQDPSFSQFIKHGRNVILSEATAMHHLAASIGVDFAKAVSMLLETRGRIIVSGIGKSGHVGRKIAATLASTGSSAFFIHPAEAAHGDLGMMMNGDILIAISFSGRTRELLPMISYAQTLQVPVIVITSQKGDVLPKEATLSLRLPELKEACPANIAPTTSTTLTMALGDALAVSMMRHRGFSRDAFKLLHPGGQIGFRLQSISRLMHEGAALPLVHCKEPMRDVLVTMSRKSFGSAGVVNDEGELMGVITDGDLRRHADHLMESAAEDVMTSDPVTMRADDMAEDALILMTEKRITSLFILGKNGAKQPVGLLHIHDLTRMGL
>NC_018145.1|WP_011241301.1|1783182_1783416_-|phosphoribosylformylglycinamidine-synthase-subunit-PurS
MKANVHVTLKNGVLDPQGKAIHHALERLGFSGVNNVRVGRLIELDLDDNVSDQEIEDMCRKLLANMVIESFRIEKVA
>NC_018145.1|WP_014849363.1|1782517_1783183_-|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MKAAVLVFPGSNCDRDLAVAIEKICGTKPLMVWHQESELPDDLDLIAVPGGFSYGDYLRSGAMAARSAVMPAVIKQAERGVPVLGICNGFQILTEAGLLPGALMRNAGLSFICRNVGLEIQNTTSPFTRLYKKNQKIHLPVAHHDGNYTADEATLDQLEDEDRVALRYTESVNGSARNIAGVLNKKGNVLGLMPHPERMIEDAHGGKDGYNMFASLMQVMA
>NC_018145.1|WP_014849362.1|1781492_1782041_-|DUF308-domain-containing-protein
MRRLFSENRSWSWTMAYAVCQILFGIAAICFPFTMSIASGLFFGWILIVAAIFAIISGFSSRHIRGHWLDIICGVIAFITGVIAIEYPVASALTIVWLIACWLLLVGLTQLFIAFRIVTERNWLILRGVINTLIALFLFFSNDKTALAFLGLAVGFAFVSEGVGMAMLALRLKRLQEEDIIL
>NC_018145.1|WP_141914866.1|1780210_1780968_+|IS5-family-transposase
MSDLFWLTDEQMGRLRPFFPKSHGKPRVDDRRVLSGIIFVNRNGMRWRDAPREYGPHKTLYNRWKRWSDMGIFSRMMDGLAAGRAEPQTIMIDATYLKAHRTASSLRPKKGDPGRLIGRTKGGMNTKLHAVTDQNGRPLSFFMTAGQISDYTGAAALLDSLPAAQWMLGDRGYDADWFRDALEEKGIKPCIPGRKSRGKPVKYDKRKYKRRNRIEIMFGRLKDWRRIATRYDRSPTVFFSAVCLAATIMFWL
>NC_018145.1|WP_014849361.1|1776320_1779845_+|DNA-polymerase-III-subunit-alpha
MPYTPFVPLRIFSGFTMLEGAIEPKDITQHAKKMGFPAAGICDRNGLYGVMTFSDSGKKDGVQPIIGSLLAVARPLRGGEASGQELKIDWLPLYAQDEDGYNNLCALVSHAHLGRPLELPPHVSMEFLEQHSQGLLALTGGKEGALARLLAEEQQSEAEAYLTLLQKIFPDRLYIELSRRSEEIEEAAEDGLIDLAYDRNIPLVATNPVCFLEADFHPAHDAMLCIADSAYVDSPDRRHSSPEAWMKSGEEMARLFEDIPEAIQNSLVIAQRCAVAAPVRKPILPSLAGDREGETLMLRKDAWAGLEARLAAMKTPVDRKAYEERLQYELNIIENMGFPGYFLIVADFIKWAKSNQIPVGPGRGSGAGSVVAWALTITNLDPLQLGLLFERFLNPERVSMPDFDIDFCETRRSEVISYVQHKYGLDHVAQIITFGRMKARAVLKDTGRVLQMSYGQVDRLAKLVPSQASDPWTLDRALNGVPEIASAYENEEDVHRLLDLAMKLEGLPRHSSTHAAGVVIGDRPLHQLVPLYRDPRSDFPVTQFDMKYVEKTGLVKFDFLGLKTLSVLNKAVQMLKARGVEVDLDHIPLDDEAVFELLKQGDTVGVFQLESEGMRRTLAAVKPTRFEDIIALVALYRPGPMDNIPSFGARKNGGEEIVYPHPLLEPVLKETYGIIVYQEQVMQAAQVLAGYSLGEADLLRRAMGKKIQAEMDAQRSRFVEGSQKHDITEAQANQLFDLIDKFAGYGFNKSHAAAYALVAYQTAWLKAHYRAEFYAAAMCFDMALTDKLQVFVDDMRRSGLRYLPPDINRSQSDFTVEEGCVRYALGALKGVGEKAMDDICQEREKNGAFKSLDDFANRINPEHLNRRQLESLASAGAFDSLGVDRCAVKHSSEMIIGTAANIHRMRKSGQGGLFGMEEMAMPSIKLPEDKIWSLTERMNAEKEAFGFFFSSHPIDNYRSLLSGLRIRSRADINRLAPPSYPQDDENPQDYRKKRIATQMAAMIEDVRWRDSARGRRYMMVAASDASGQFFASCFDEKATKDLEQAAKEKACVLMDVELDWRPGDEAPRVSIRAIQLCENLAPSVRLKMTVATGEAETLPALSELVNRYRGGQGELYIRALLPDGASTDFLVGRHYILSAELKAKIKRLSGIQAVDLKSFVEEKQANSPKQPAYA
>NC_018145.1|WP_014849360.1|1775665_1775968_-|ferrous-iron-transport-protein-A
MRLNEMPLKKATVITDIDWSALPPEIGRRLRDLGFHKGAEVELQHFAPISRDPIACRVDRILIAIRQKEASVISVKDPDAAPEPALSEKASSSRSTVGQA
>NC_018145.1|WP_014849368.1|1796061_1796991_-|DMT-family-transporter
MEKKGITIALIAYLAFTISDAGSKLLDGKINAFEIAFLGSVIAAPAIPLMRKPHESYLNIFGFYDFKIWLIRAVCVALCTFFSVVAFTRLPMTEAMALLFLLPFFVNLIALIFLHEKISFAKWVALIIGFIGTVIILRPGIRPLGVGHLAALAGAFCTGASWAVFRATNKKKGGLVTKPSRLSLYSASVVGPIVIDGAMTWNSWVTPTALQWFYLFIYGLFAAWGQIMMMIAAEYAEANTIALPQYSQMVWTVIFSYLVFHQPVDFISFVGIAVIFLSGYLTWRSGRKLVTAPLPPIANQIEKTLEAEE
>NC_018145.1|WP_014849369.1|1797447_1800468_-|TonB-dependent-receptor
MIRRHLKNAFMTTGMVAGVIAWSTPVFAQETSQGIPQQSGTSADSNSVNNAAADNAAIPTMASAPAASELAPPSGTITVTGSRLPPGITSTSPITSVNAKEIGKQGYTRIEDMLNRMPQFYGNQNSAVSNGSTGTADANLRNLGSQRTLVLINGRRVMPGDTTSQAADLNAIPSSLIKRVDVLTGGASSVYGSDAVAGVVNFVMDTDYEGFHADAQYNVLNGDNDSRTMRSILRNSPIAGTKTPTNTPFDGWGFNANLKFGAGTKDGRGHIVAYLGYRRQAAVTGADRDYSACPIKGSGTDGAICSGSMAASPSSILVGQNGDPYQFTDGGIVEGTNKYNYNTLSNIQRPDQRYTAGFFAHYDVTDGFKPYAEFQFMDDRSSAQIAPSGTFGYGRVSCDNPFLTSQAQSILCSVGNTTSSIDSRGKQYDTSTAQFFKRNVEGGPRIDTMKHTSYRGVIGSKGEIVKGLTYDVYGQYGSTIVSSYSTNDFSIRKLNNAMNVVNYNGTPTCRSVIDGTDTDCVPYNIFSGNGPSQKSIDYLNTPAVTTGSTQETVVSGSLTFDGSEYGIQLPTASHGLSVNVGAEYRREKMKAYSDYEVASGDLASQGGPRLSSQGKYDVKELFVEAALPIMDHRRGVNDLTLTGGFRYSDYSSTGSVQSYKGQMIYSPIKGIALRGGYNRAVRAPNIQELYSPTQVALDGSTDPCASSSPTMTAAQCELMGVTKSQYGKIADNPAYQYNGMTGGNPNLKPETANTFTGGISLTPFRRFSFTADFYDIKIKNIIQTLGADTILQLCGNKGLYCDHIHRDGNGSLWRSQEGYVTDTKLNIGSLATRGVDFGVNYSYPLGGKYGNLSSSFNGTWLLNYKTNPGGGAPVYNCAGLYGAVCGMIMPKWRHQMRVSWDLPAGYGFSAMWRFIGGAKSDVGTTANPNGTAISSIDKKIGNVSYLDLTAYYKVTDKVTLSAGVNNVIGTRPPLVTGQNGGDTTNSYSGIYDVYGRYIFAGLSYDF
>NC_018145.1|WP_014849370.1|1800974_1801553_+|hypothetical-protein
MKSFLSKKMGMFLCLSMAITLLPAKAAKNQNNFKDSVLFGKLLACRSLNDDISRLHCFDENIKALDDANTHHDILVVDREAIVARQKQSFGFAPPVLALPKKDNVSSHSIKKDPAADDVIHEITDKASFVSQDSEGHWIIGFSNGARWRQIDDQTVPNEPHVGSVIRLRKAALGSFVANIDKQSAIKMRRIQ
>NC_018145.1|WP_014849371.1|1801701_1801932_+|DUF2093-domain-containing-protein
MLIPGFKKDQPAKVEYLDGHFRLLSRGSHVICAISGKSIDLDSLHYWSVEKQEPYASAYEAEIAYSREQGAKKDNA
>NC_018145.1|WP_011241291.1|1802136_1803072_+|ribose-phosphate-pyrophosphokinase
MKLLAGNSNLPISQAIADYLEIDLTKASVRRFADEEIFVEIRENVRGQDVFVIQSTCWPTNDNLMELLICIDALKRASARRITAVIPYFGYARQDRKPGPRTPISAKLVANLITVAGASRVLSVDLHAGQIQGFFDIPTDNLYAAPVMSADILARFPDKKLTVVSPDVGGVVRARALAKRLDNAPLAIVDKRRERPGESEVMNIIGDVSGRFCILIDDIVDSAGTLCNAAEALLNAGAEGVIAYVTHGVLSGAAVARVEKSSLQELVVTDSIGMRPEVEQCAKIRQLSLAPLLAEAIRRIADETSVSSLFD
>NC_018145.1|WP_014849372.1|1803117_1803897_+|inositol-monophosphatase-family-protein
MSRSAYEDDIRLAHRLADVAADIIRPFFRAPLTIDLKADHSPVTKADRGAEQAMRAILEQERPEDGIFGEEMGISRPDARRLWVLDPIDGTRAFIGGRASFGTLIALVEDGRPVLGIINQPIHQERWVGVKDLPTRFNGEVIHTRSCPALDHALLATTSPWLFEKEGEVHFDKIRLKCRDTLLGGDCYNYGLLSLGHCDLVVEQGLKFYDFAALVPIVEGAGGIMRDWQNRPLNKNSVGEVIAAGDHHLIEPALSAMEL
>NC_018145.1|WP_011241289.1|1804042_1804246_+|50S-ribosomal-protein-L35
MPKLKTKSGVKKRFKFTANGKVKHGVAGKRHRLISHNAKYIRQHRRTDVVSSTENRTIKAWAPYGLN
>NC_018145.1|WP_011241288.1|1804259_1804637_+|50S-ribosomal-protein-L20
MARVKRGTTTRAKHNRILDQAKGYYGRRKNTIRIARQAVEKAGQYAYRDRKVKKRSFRALWIQRINAAVRAEGLTYGVFMYGLKLAGLDLDRKVLADLAMNESAAFGAIIAQVKSALPEGARVAA
>NC_018145.1|WP_041573222.1|1804925_1806026_+|phenylalanine--tRNA-ligase-subunit-alpha
MTDLDNLKADLIGQISQLGDLAGLESVRVHALGKQGVVTALLKSLGKMTPEERQEKGPVIHSLRQAVAQGIADRKQALETALLNEKLASETIDLSLPSPKMPKGSLHPVSQVMDELAEIFADLGFAVASGPEIEDEWHNFSALNIPESHPARAMHDTFYFEPQEGASDKGDKGRMLLRTHTSPVQIRTMQGQEPPIRIIAPGRTYRSDSDATHTPMFHQVEGLVIDKGVHLGHLKWTLETFVRAYFERDDIVLRLRPSYFPFTEPSMEVDVGYTLEKGRRIIGGKQPDGWMEILGSGMVHPNVITACGLDPNVWQGFAFGCGIDRLAMLKYGMDDLRAFFDGDLRWLRHFGFAALDVPTLSGGVGA
>NC_018145.1|WP_014849374.1|1806022_1808392_+|phenylalanine--tRNA-ligase-subunit-beta
MKFTLSWLKEHLETEASVQEIADTLTRIGHEVESVHNPADGLEAFRIARILTAERHPQADRLQILAVDVGESEPLQVVCGAANARAGLVGVFAAPGVYVPGIDVTLKIASIRGVESRGMMCSIRELGLGDEHEGILDLPHEAPVGQSYVEWAGLDDPVFDVAITPDRQDCMGVRGLARDLATAGIGRLKPLAIPRVPVTDAAPAEIAIEDKEGCPAFFGQLIHGIQNGPSPEWMARRLRAIGFRPTSALVDITNYIMFDLGRPLHVYDAGAIKGKLTARKAQNNEKIEALNGKSYDLDPSITVIADDQGIKNIAGIMGAEKGSVSGSTTDVIIECAYFDPAAVSQAGQKLGLASDARIRFERGVDPAFLNEGLQIAARMVLDFCGGKATQAVTLGEAPSAVPVISYDPSYVTSLAAMDVAPARQREILEQLGFAIDAGWRVRVPSFRRDVSVVADIVADIVRIEGLDNVPSTALDRGDGVARPIATHGQLTERRVRRAAAAFGMNEAVTWSFISEKDADIFGGAFWKLANPISEDMKVMRPSLLPGLLTAAKRNRDRGQSTIRLFEVGRRYLQEAERPTLGLIFAGERMSRDWQYGKSQNFDAYDAKTAVSAMLDSVGMPVEKLQLLGDAGDVYHPGRSGRLCLGPKNTLAVFGEIHPAILAEFNMEGPVIGAEIFLDALPLRKNSGQLRQPYAPSMLQPVFRDFAFLLPKDVPAADLVRSIAGADKNAIVEARIFDVFTGETIDENEKSLGIEVMLQPAEKSFTDAELQVISDKIVAAAAKKGARLRA

Crispr_ID: NC_018145_5

• CRISPR_ID: NC_018145_5
• CRISPR_location: 1794090-1794184
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_018145_5

Consensus_repeat	Method
TCTCTTTCTGCGCCCGAAGTTGG	CRISPRCasFinder

spacers of NC_018145_5

>5.1|1794113|49|NC_018145|CRISPRCasFinder
GGCAGCTACCAAGGAGACGGCTTCTTCACCGCTTGAAGCTGGAAAAATA

CRISPR arrays and Neighbor proteins around NC_018145_5

CRISPR arrays

The CRISPR arrays of NC_018145_5

>merge|NC_018145|5|1794090-1794184|CRISPRCasFinder
TCTCTTTCTGCGCCCGAAGTTGGGGCAGCTACCAAGGAGACGGCTTCTTCACCGCTTGAAGCTGGAAAAATATCTCTTTCTGCGCCTGAAGTTGG

>NC_018145|5|5|1794090-1794184|CRISPRCasFinder
TCTCTTTCTGCGCCCGAAGTTGG	GGCAGCTACCAAGGAGACGGCTTCTTCACCGCTTGAAGCTGGAAAAATA
TCTCTTTCTGCGCCTGAAGTTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018145.1|WP_014849365.1|1789510_1792810_+|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|182589
NC_018145.1|WP_011241288.1|1804259_1804637_+|50S-ribosomal-protein-L20	unknown	unknown	gnl|CDD|179959
NC_018145.1|WP_011241291.1|1802136_1803072_+|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl|CDD|234929
NC_018145.1|WP_014849363.1|1782517_1783183_-|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl|CDD|235140
NC_018145.1|WP_011241300.1|1783588_1784599_-|KpsF/GutQ-family-sugar-phosphate-isomerase	unknown	unknown	gnl|CDD|182814
NC_018145.1|WP_014849374.1|1806022_1808392_+|phenylalanine--tRNA-ligase-subunit-beta	unknown	unknown	gnl|CDD|234804
NC_018145.1|WP_014849372.1|1803117_1803897_+|inositol-monophosphatase-family-protein	unknown	unknown	gnl|CDD|238819
NC_018145.1|WP_041573222.1|1804925_1806026_+|phenylalanine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl|CDD|234780
NC_018145.1|WP_014849361.1|1776320_1779845_+|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl|CDD|235554
NC_018145.1|WP_014849360.1|1775665_1775968_-|ferrous-iron-transport-protein-A	unknown	unknown	gnl|CDD|377199
NC_018145.1|WP_141914866.1|1780210_1780968_+|IS5-family-transposase	unknown	unknown	gnl|CDD|379129
NC_018145.1|WP_014849369.1|1797447_1800468_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|238657
NC_018145.1|WP_011241289.1|1804042_1804246_+|50S-ribosomal-protein-L35	unknown	unknown	gnl|CDD|234676
NC_018145.1|WP_014849364.1|1786415_1789514_+|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|182501
NC_018145.1|WP_014849371.1|1801701_1801932_+|DUF2093-domain-containing-protein	unknown	unknown	gnl|CDD|226423
NC_018145.1|WP_014849362.1|1781492_1782041_-|DUF308-domain-containing-protein	unknown	unknown	gnl|CDD|225786
NC_018145.1|WP_011241299.1|1785053_1786376_+|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|183194
NC_018145.1|WP_011241301.1|1783182_1783416_-|phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl|CDD|376904
NC_018145.1|WP_014849370.1|1800974_1801553_+|hypothetical-protein	unknown	unknown	unknown
NC_018145.1|WP_014849368.1|1796061_1796991_-|DMT-family-transporter	unknown	unknown	gnl|CDD|223769

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018145.1|WP_014849365.1|1789510_1792810_+|efflux-RND-transporter-permease-subunit	gnl|CDD|182589	PRK10614, PRK10614, multidrug efflux system subunit MdtC; Provisional.	0
NC_018145.1|WP_011241288.1|1804259_1804637_+|50S-ribosomal-protein-L20	gnl|CDD|179959	PRK05185, rplT, 50S ribosomal protein L20; Provisional.	3.98401e-62
NC_018145.1|WP_011241291.1|1802136_1803072_+|ribose-phosphate-pyrophosphokinase	gnl|CDD|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NC_018145.1|WP_014849363.1|1782517_1783183_-|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl|CDD|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	2.56052e-141
NC_018145.1|WP_011241300.1|1783588_1784599_-|KpsF/GutQ-family-sugar-phosphate-isomerase	gnl|CDD|182814	PRK10892, PRK10892, arabinose-5-phosphate isomerase KdsD.	1.42528e-87
NC_018145.1|WP_014849374.1|1806022_1808392_+|phenylalanine--tRNA-ligase-subunit-beta	gnl|CDD|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	0
NC_018145.1|WP_014849372.1|1803117_1803897_+|inositol-monophosphatase-family-protein	gnl|CDD|238819	cd01641, Bacterial_IMPase_like_1, Predominantly bacterial family of Mg++ dependend phosphatases, related to inositol monophosphatases. These enzymes may dephosphorylate fructose-1,6-bisphosphate, inositol monophospate, 3'-phosphoadenosine-5'-phosphate, or similar substrates.	4.43616e-113
NC_018145.1|WP_041573222.1|1804925_1806026_+|phenylalanine--tRNA-ligase-subunit-alpha	gnl|CDD|234780	PRK00488, pheS, phenylalanyl-tRNA synthetase subunit alpha; Validated.	0
NC_018145.1|WP_014849361.1|1776320_1779845_+|DNA-polymerase-III-subunit-alpha	gnl|CDD|235554	PRK05673, dnaE, DNA polymerase III subunit alpha; Validated.	0
NC_018145.1|WP_014849360.1|1775665_1775968_-|ferrous-iron-transport-protein-A	gnl|CDD|377199	pfam04023, FeoA, FeoA domain. This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.	8.63252e-16
NC_018145.1|WP_141914866.1|1780210_1780968_+|IS5-family-transposase	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.56061e-22
NC_018145.1|WP_014849369.1|1797447_1800468_-|TonB-dependent-receptor	gnl|CDD|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	1.02111e-28
NC_018145.1|WP_011241289.1|1804042_1804246_+|50S-ribosomal-protein-L35	gnl|CDD|234676	PRK00172, rpmI, 50S ribosomal protein L35; Reviewed.	9.09166e-21
NC_018145.1|WP_014849364.1|1786415_1789514_+|efflux-RND-transporter-permease-subunit	gnl|CDD|182501	PRK10503, PRK10503, MdtB/MuxB family multidrug efflux RND transporter permease subunit.	0
NC_018145.1|WP_014849371.1|1801701_1801932_+|DUF2093-domain-containing-protein	gnl|CDD|226423	COG3908, COG3908, Uncharacterized protein conserved in bacteria [Function unknown].	4.11974e-21
NC_018145.1|WP_014849362.1|1781492_1782041_-|DUF308-domain-containing-protein	gnl|CDD|225786	COG3247, HdeD, Uncharacterized conserved protein [Function unknown].	1.10757e-14
NC_018145.1|WP_011241299.1|1785053_1786376_+|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl|CDD|183194	PRK11556, PRK11556, MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit.	9.6446e-106
NC_018145.1|WP_011241301.1|1783182_1783416_-|phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl|CDD|376904	pfam02700, PurS, Phosphoribosylformylglycinamidine (FGAM) synthase. This family forms a component of the de novo purine biosynthesis pathway.	5.97042e-35
NC_018145.1|WP_014849368.1|1796061_1796991_-|DMT-family-transporter	gnl|CDD|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.49223e-12

Protein sequences

>NC_018145.1|WP_014849365.1|1789510_1792810_+|efflux-RND-transporter-permease-subunit
MNLSRPFISRPIGTTLLTIGIALAGIIAYFKLPVAPLPQIDFPVIVVQASMAGASPDTMANSIAQPLERRLGVIADVTEMTSTSSVGSTQIALEFGLDRDINGAAREVQAAISAARADLPSTLQSNPSYLKVNPSMMPVMVLALTSDSKTPGQIYETVSNLVSQRLSQVSGVGEVEIGGGSLPGVRIDVSPYALSRFGLSLEDVRATIESANANRPKGALESPDGHHFQIYTNQLGRDAKLYGDLVVAWRDGTTAIRLKDIASVTDGVADTRNLGLFNGHPAVIVLITQQPGANLINLVDSLRAELPHLEKMLPSDVHVTVANDRTSSIRSTLNEVRLTLIISLILVIAVVGVFLRNLSAVVIPAVAASVSLLGTFAVMYFAGFSLNNLSMMAIIVATGFVIDDAIVVLENIARHLENGMGRMEAALLGAQEVGFTVLSISLSLVAVFIPLLFLGGIGGRLFREFAVSLSAAVLISMVISLTTTPMMCAWMLSPRKEDKKQGRIADFFEKSFAHVEKAYSYALNWALSMKPLMLVLFLLVLVLTVYLYAVVPKSFFPQQDSPILMAGVRADRSSSFQTMEKKLTKTVNILRQEKQVSTVIGFTGGKRSGSAFLMVELKPWGERKEKATTVINRLRPKLAQLTGISVFLSPMQDLRMGARSSDATYQYTLISDDSKALQDWVPKLTQALQTSNILTDVDNDLALNGIESMVNIDRDSASRLGISARNVDNALYDSFGQRQIATIYEDINQYPVVFEWTPKDQQGPQALQNLYIPENSSTNSASSTNTTAIAGTGTNAAGATSVANDSSALSVNSTGSGNSGDANSANPSLRDPSTGSALNTSASTMVPLPAIAKFSLHATDLSIQHDNGEAAATISFNLKSGHNLNEAQSEIKAKMAQLMVPANIRGNFAGTAKLGNDSGSQALLLLAALITIYIVLGILYENLIHPITVISTLPAAGVGAVLALMIIHMDFSLIALIGVFLLMGIVKKNAILVIDVALHLQREQGLSAEEAMRQSCVLRFRPIIMTTLAAALGVVPLAIGFGEGSEFRQPLGVTIIGGLVVSQMLTLFTTPVIYIYFDRLSRWRPWRRKAKAENRLEKA
>NC_018145.1|WP_014849364.1|1786415_1789514_+|efflux-RND-transporter-permease-subunit
MNPSRLFILRPVATSLIVIAIVLAGLLGFHYMSLSALPEVDYPTIQVSTLYPGASPEVISQTVSAPLERQFGQMSGLSRMTTKSAAGASVITLQFGLNEALDVAEQEVQAAINAANALLPADLPAPPVYAKVNPADSPVLTLAATSDTMPLTDVQNLVQTRLAQKISQVSGVGLVELSGGQRPAMRIQADTQALASYGISLSTLRTAIDNANANSAKGSFDGPTRSWQINANDQLLTVEDYKNLIIAMRNSRPVRMSDVAQVVAGAENNHLGAYYNITPAVIINVRRQPGANVIATVDNIKKQLPELEAGLPAGLKISVVADRTTGIRASIEHVEVELVLAVVMVILVIFFFLHSIRATLIAAVAVPISLIGSFAAMYMMNYSLNNLSLMALTIASGFVVDDAIVMIENIERHIEAGVAPFQAALKGAQEIGFTIISLTISLIAVLIPLLFMSDVVGRLFREFAMTLAITILISAVVSLTLTPMLSARLLVAHRHKNPIGDRIQKGFERLEYHYEHGLRWVLGHQTLTLVLTIVTFIGTALFYVAIPKGLFPLQATGQLRIQTDTSPDVSYSRMAELQKQAAAKILQDPAVENLSVMSGVDGVTNSALNQGVMLVNLKEGISDEQPVIKRLYQAVGAVAGIRAHIQPVQDLTVDTDTGPTRFRLSVEGADTDSVHKAARAIADSLGQSKKLTDVYTDADAKGDAVYVNIDRETASRLSVTVADIDDTLYSAFGQRIISTIFTETNQYRVILEARPNLLNSIESLGHLNLAGSGTLPTPLNGFSTLKIGQAPLQIMHVAQFPAATVGFDLASNTALGDGVKAVRAQIARLDLPSGITTTLLGAASAYEKALGNQILLIFAALVCVYIVLGVLYESYIHPLTILSTLPSASVGAILALWVSGHDLDIIGIIGIILLIGIVKKNAIMMIDFAIAAEREEKKSPEEAIFNAATLRFRPILMTTLAALFAAIPLMIGHGSGAELRRPLGLAIFGGLLASQMLTVFTTPVIYLFFDRLGQKIAYLRRHKDSENEVKSA
>NC_018145.1|WP_011241299.1|1785053_1786376_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MQEETDGQNMPHPDKKQETIEPSSAPSLSKKGKLKSWIISLIVLALIFLLIAYITHNNKANTQKSASHGHHGKSSKMGPPGDDGDMPVTVSIVKSKTADVPIVVEALGTVTPVSTITVKPQVSGYIKRILYTEGQMVKEGQPLALIDPRLYSAQLVQNEGALRRDIAQLENARIQLARDRQLGSDSIAKQDVDTQAATVHQLEGTVEADRGAVEYSKVNLGYTTIPSPVTGRVGLRPIDQGNYIAAGDSSGVAVVTSLDPIDVVFTMAQDFVPEVEKQVRTGRQLTGTAYDRTKTENLGEGWLLTLDNRIDTTSGTVKGKIRFHNATGKLFPNQFVNIHLNVETLRQVVTVPSTAIREADNGSYVWLVDKQRKVHRHFVTTGNSYGDNIVILKGLDANQLVVTEGGDRLIENSEVQTPAESSKEMNIKPRDNATKTQAKS
>NC_018145.1|WP_011241300.1|1783588_1784599_-|KpsF/GutQ-family-sugar-phosphate-isomerase
MQQSLQTVDDSTPYQDPSFSQFIKHGRNVILSEATAMHHLAASIGVDFAKAVSMLLETRGRIIVSGIGKSGHVGRKIAATLASTGSSAFFIHPAEAAHGDLGMMMNGDILIAISFSGRTRELLPMISYAQTLQVPVIVITSQKGDVLPKEATLSLRLPELKEACPANIAPTTSTTLTMALGDALAVSMMRHRGFSRDAFKLLHPGGQIGFRLQSISRLMHEGAALPLVHCKEPMRDVLVTMSRKSFGSAGVVNDEGELMGVITDGDLRRHADHLMESAAEDVMTSDPVTMRADDMAEDALILMTEKRITSLFILGKNGAKQPVGLLHIHDLTRMGL
>NC_018145.1|WP_011241301.1|1783182_1783416_-|phosphoribosylformylglycinamidine-synthase-subunit-PurS
MKANVHVTLKNGVLDPQGKAIHHALERLGFSGVNNVRVGRLIELDLDDNVSDQEIEDMCRKLLANMVIESFRIEKVA
>NC_018145.1|WP_014849363.1|1782517_1783183_-|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MKAAVLVFPGSNCDRDLAVAIEKICGTKPLMVWHQESELPDDLDLIAVPGGFSYGDYLRSGAMAARSAVMPAVIKQAERGVPVLGICNGFQILTEAGLLPGALMRNAGLSFICRNVGLEIQNTTSPFTRLYKKNQKIHLPVAHHDGNYTADEATLDQLEDEDRVALRYTESVNGSARNIAGVLNKKGNVLGLMPHPERMIEDAHGGKDGYNMFASLMQVMA
>NC_018145.1|WP_014849362.1|1781492_1782041_-|DUF308-domain-containing-protein
MRRLFSENRSWSWTMAYAVCQILFGIAAICFPFTMSIASGLFFGWILIVAAIFAIISGFSSRHIRGHWLDIICGVIAFITGVIAIEYPVASALTIVWLIACWLLLVGLTQLFIAFRIVTERNWLILRGVINTLIALFLFFSNDKTALAFLGLAVGFAFVSEGVGMAMLALRLKRLQEEDIIL
>NC_018145.1|WP_141914866.1|1780210_1780968_+|IS5-family-transposase
MSDLFWLTDEQMGRLRPFFPKSHGKPRVDDRRVLSGIIFVNRNGMRWRDAPREYGPHKTLYNRWKRWSDMGIFSRMMDGLAAGRAEPQTIMIDATYLKAHRTASSLRPKKGDPGRLIGRTKGGMNTKLHAVTDQNGRPLSFFMTAGQISDYTGAAALLDSLPAAQWMLGDRGYDADWFRDALEEKGIKPCIPGRKSRGKPVKYDKRKYKRRNRIEIMFGRLKDWRRIATRYDRSPTVFFSAVCLAATIMFWL
>NC_018145.1|WP_014849361.1|1776320_1779845_+|DNA-polymerase-III-subunit-alpha
MPYTPFVPLRIFSGFTMLEGAIEPKDITQHAKKMGFPAAGICDRNGLYGVMTFSDSGKKDGVQPIIGSLLAVARPLRGGEASGQELKIDWLPLYAQDEDGYNNLCALVSHAHLGRPLELPPHVSMEFLEQHSQGLLALTGGKEGALARLLAEEQQSEAEAYLTLLQKIFPDRLYIELSRRSEEIEEAAEDGLIDLAYDRNIPLVATNPVCFLEADFHPAHDAMLCIADSAYVDSPDRRHSSPEAWMKSGEEMARLFEDIPEAIQNSLVIAQRCAVAAPVRKPILPSLAGDREGETLMLRKDAWAGLEARLAAMKTPVDRKAYEERLQYELNIIENMGFPGYFLIVADFIKWAKSNQIPVGPGRGSGAGSVVAWALTITNLDPLQLGLLFERFLNPERVSMPDFDIDFCETRRSEVISYVQHKYGLDHVAQIITFGRMKARAVLKDTGRVLQMSYGQVDRLAKLVPSQASDPWTLDRALNGVPEIASAYENEEDVHRLLDLAMKLEGLPRHSSTHAAGVVIGDRPLHQLVPLYRDPRSDFPVTQFDMKYVEKTGLVKFDFLGLKTLSVLNKAVQMLKARGVEVDLDHIPLDDEAVFELLKQGDTVGVFQLESEGMRRTLAAVKPTRFEDIIALVALYRPGPMDNIPSFGARKNGGEEIVYPHPLLEPVLKETYGIIVYQEQVMQAAQVLAGYSLGEADLLRRAMGKKIQAEMDAQRSRFVEGSQKHDITEAQANQLFDLIDKFAGYGFNKSHAAAYALVAYQTAWLKAHYRAEFYAAAMCFDMALTDKLQVFVDDMRRSGLRYLPPDINRSQSDFTVEEGCVRYALGALKGVGEKAMDDICQEREKNGAFKSLDDFANRINPEHLNRRQLESLASAGAFDSLGVDRCAVKHSSEMIIGTAANIHRMRKSGQGGLFGMEEMAMPSIKLPEDKIWSLTERMNAEKEAFGFFFSSHPIDNYRSLLSGLRIRSRADINRLAPPSYPQDDENPQDYRKKRIATQMAAMIEDVRWRDSARGRRYMMVAASDASGQFFASCFDEKATKDLEQAAKEKACVLMDVELDWRPGDEAPRVSIRAIQLCENLAPSVRLKMTVATGEAETLPALSELVNRYRGGQGELYIRALLPDGASTDFLVGRHYILSAELKAKIKRLSGIQAVDLKSFVEEKQANSPKQPAYA
>NC_018145.1|WP_014849360.1|1775665_1775968_-|ferrous-iron-transport-protein-A
MRLNEMPLKKATVITDIDWSALPPEIGRRLRDLGFHKGAEVELQHFAPISRDPIACRVDRILIAIRQKEASVISVKDPDAAPEPALSEKASSSRSTVGQA
>NC_018145.1|WP_014849368.1|1796061_1796991_-|DMT-family-transporter
MEKKGITIALIAYLAFTISDAGSKLLDGKINAFEIAFLGSVIAAPAIPLMRKPHESYLNIFGFYDFKIWLIRAVCVALCTFFSVVAFTRLPMTEAMALLFLLPFFVNLIALIFLHEKISFAKWVALIIGFIGTVIILRPGIRPLGVGHLAALAGAFCTGASWAVFRATNKKKGGLVTKPSRLSLYSASVVGPIVIDGAMTWNSWVTPTALQWFYLFIYGLFAAWGQIMMMIAAEYAEANTIALPQYSQMVWTVIFSYLVFHQPVDFISFVGIAVIFLSGYLTWRSGRKLVTAPLPPIANQIEKTLEAEE
>NC_018145.1|WP_014849369.1|1797447_1800468_-|TonB-dependent-receptor
MIRRHLKNAFMTTGMVAGVIAWSTPVFAQETSQGIPQQSGTSADSNSVNNAAADNAAIPTMASAPAASELAPPSGTITVTGSRLPPGITSTSPITSVNAKEIGKQGYTRIEDMLNRMPQFYGNQNSAVSNGSTGTADANLRNLGSQRTLVLINGRRVMPGDTTSQAADLNAIPSSLIKRVDVLTGGASSVYGSDAVAGVVNFVMDTDYEGFHADAQYNVLNGDNDSRTMRSILRNSPIAGTKTPTNTPFDGWGFNANLKFGAGTKDGRGHIVAYLGYRRQAAVTGADRDYSACPIKGSGTDGAICSGSMAASPSSILVGQNGDPYQFTDGGIVEGTNKYNYNTLSNIQRPDQRYTAGFFAHYDVTDGFKPYAEFQFMDDRSSAQIAPSGTFGYGRVSCDNPFLTSQAQSILCSVGNTTSSIDSRGKQYDTSTAQFFKRNVEGGPRIDTMKHTSYRGVIGSKGEIVKGLTYDVYGQYGSTIVSSYSTNDFSIRKLNNAMNVVNYNGTPTCRSVIDGTDTDCVPYNIFSGNGPSQKSIDYLNTPAVTTGSTQETVVSGSLTFDGSEYGIQLPTASHGLSVNVGAEYRREKMKAYSDYEVASGDLASQGGPRLSSQGKYDVKELFVEAALPIMDHRRGVNDLTLTGGFRYSDYSSTGSVQSYKGQMIYSPIKGIALRGGYNRAVRAPNIQELYSPTQVALDGSTDPCASSSPTMTAAQCELMGVTKSQYGKIADNPAYQYNGMTGGNPNLKPETANTFTGGISLTPFRRFSFTADFYDIKIKNIIQTLGADTILQLCGNKGLYCDHIHRDGNGSLWRSQEGYVTDTKLNIGSLATRGVDFGVNYSYPLGGKYGNLSSSFNGTWLLNYKTNPGGGAPVYNCAGLYGAVCGMIMPKWRHQMRVSWDLPAGYGFSAMWRFIGGAKSDVGTTANPNGTAISSIDKKIGNVSYLDLTAYYKVTDKVTLSAGVNNVIGTRPPLVTGQNGGDTTNSYSGIYDVYGRYIFAGLSYDF
>NC_018145.1|WP_014849370.1|1800974_1801553_+|hypothetical-protein
MKSFLSKKMGMFLCLSMAITLLPAKAAKNQNNFKDSVLFGKLLACRSLNDDISRLHCFDENIKALDDANTHHDILVVDREAIVARQKQSFGFAPPVLALPKKDNVSSHSIKKDPAADDVIHEITDKASFVSQDSEGHWIIGFSNGARWRQIDDQTVPNEPHVGSVIRLRKAALGSFVANIDKQSAIKMRRIQ
>NC_018145.1|WP_014849371.1|1801701_1801932_+|DUF2093-domain-containing-protein
MLIPGFKKDQPAKVEYLDGHFRLLSRGSHVICAISGKSIDLDSLHYWSVEKQEPYASAYEAEIAYSREQGAKKDNA
>NC_018145.1|WP_011241291.1|1802136_1803072_+|ribose-phosphate-pyrophosphokinase
MKLLAGNSNLPISQAIADYLEIDLTKASVRRFADEEIFVEIRENVRGQDVFVIQSTCWPTNDNLMELLICIDALKRASARRITAVIPYFGYARQDRKPGPRTPISAKLVANLITVAGASRVLSVDLHAGQIQGFFDIPTDNLYAAPVMSADILARFPDKKLTVVSPDVGGVVRARALAKRLDNAPLAIVDKRRERPGESEVMNIIGDVSGRFCILIDDIVDSAGTLCNAAEALLNAGAEGVIAYVTHGVLSGAAVARVEKSSLQELVVTDSIGMRPEVEQCAKIRQLSLAPLLAEAIRRIADETSVSSLFD
>NC_018145.1|WP_014849372.1|1803117_1803897_+|inositol-monophosphatase-family-protein
MSRSAYEDDIRLAHRLADVAADIIRPFFRAPLTIDLKADHSPVTKADRGAEQAMRAILEQERPEDGIFGEEMGISRPDARRLWVLDPIDGTRAFIGGRASFGTLIALVEDGRPVLGIINQPIHQERWVGVKDLPTRFNGEVIHTRSCPALDHALLATTSPWLFEKEGEVHFDKIRLKCRDTLLGGDCYNYGLLSLGHCDLVVEQGLKFYDFAALVPIVEGAGGIMRDWQNRPLNKNSVGEVIAAGDHHLIEPALSAMEL
>NC_018145.1|WP_011241289.1|1804042_1804246_+|50S-ribosomal-protein-L35
MPKLKTKSGVKKRFKFTANGKVKHGVAGKRHRLISHNAKYIRQHRRTDVVSSTENRTIKAWAPYGLN
>NC_018145.1|WP_011241288.1|1804259_1804637_+|50S-ribosomal-protein-L20
MARVKRGTTTRAKHNRILDQAKGYYGRRKNTIRIARQAVEKAGQYAYRDRKVKKRSFRALWIQRINAAVRAEGLTYGVFMYGLKLAGLDLDRKVLADLAMNESAAFGAIIAQVKSALPEGARVAA
>NC_018145.1|WP_041573222.1|1804925_1806026_+|phenylalanine--tRNA-ligase-subunit-alpha
MTDLDNLKADLIGQISQLGDLAGLESVRVHALGKQGVVTALLKSLGKMTPEERQEKGPVIHSLRQAVAQGIADRKQALETALLNEKLASETIDLSLPSPKMPKGSLHPVSQVMDELAEIFADLGFAVASGPEIEDEWHNFSALNIPESHPARAMHDTFYFEPQEGASDKGDKGRMLLRTHTSPVQIRTMQGQEPPIRIIAPGRTYRSDSDATHTPMFHQVEGLVIDKGVHLGHLKWTLETFVRAYFERDDIVLRLRPSYFPFTEPSMEVDVGYTLEKGRRIIGGKQPDGWMEILGSGMVHPNVITACGLDPNVWQGFAFGCGIDRLAMLKYGMDDLRAFFDGDLRWLRHFGFAALDVPTLSGGVGA
>NC_018145.1|WP_014849374.1|1806022_1808392_+|phenylalanine--tRNA-ligase-subunit-beta
MKFTLSWLKEHLETEASVQEIADTLTRIGHEVESVHNPADGLEAFRIARILTAERHPQADRLQILAVDVGESEPLQVVCGAANARAGLVGVFAAPGVYVPGIDVTLKIASIRGVESRGMMCSIRELGLGDEHEGILDLPHEAPVGQSYVEWAGLDDPVFDVAITPDRQDCMGVRGLARDLATAGIGRLKPLAIPRVPVTDAAPAEIAIEDKEGCPAFFGQLIHGIQNGPSPEWMARRLRAIGFRPTSALVDITNYIMFDLGRPLHVYDAGAIKGKLTARKAQNNEKIEALNGKSYDLDPSITVIADDQGIKNIAGIMGAEKGSVSGSTTDVIIECAYFDPAAVSQAGQKLGLASDARIRFERGVDPAFLNEGLQIAARMVLDFCGGKATQAVTLGEAPSAVPVISYDPSYVTSLAAMDVAPARQREILEQLGFAIDAGWRVRVPSFRRDVSVVADIVADIVRIEGLDNVPSTALDRGDGVARPIATHGQLTERRVRRAAAAFGMNEAVTWSFISEKDADIFGGAFWKLANPISEDMKVMRPSLLPGLLTAAKRNRDRGQSTIRLFEVGRRYLQEAERPTLGLIFAGERMSRDWQYGKSQNFDAYDAKTAVSAMLDSVGMPVEKLQLLGDAGDVYHPGRSGRLCLGPKNTLAVFGEIHPAILAEFNMEGPVIGAEIFLDALPLRKNSGQLRQPYAPSMLQPVFRDFAFLLPKDVPAADLVRSIAGADKNAIVEARIFDVFTGETIDENEKSLGIEVMLQPAEKSFTDAELQVISDKIVAAAAKKGARLRA

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_018145_3	3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR	1757117-1757148	32	NC_013784	Zymomonas mobilis subsp. mobilis ZM4 plasmid pZZM401, complete sequence	17777-17808	0	1.0
NC_018145_3	3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR	1757117-1757148	32	NZ_CP023686	Zymomonas mobilis subsp. mobilis strain ZM4 substr. 8b plasmid pZM41, complete sequence	1240-1271	0	1.0
NC_018145_3	3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR	1757117-1757148	32	NZ_CP023680	Zymomonas mobilis subsp. mobilis strain ZM4 substr. 2032 plasmid pZM36, complete sequence	1240-1271	0	1.0
NC_018145_3	3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR	1757117-1757148	32	NZ_CP003712	Zymomonas mobilis subsp. mobilis NRRL B-12526 plasmid pZM1252603, complete sequence	28072-28103	0	1.0
NC_018145_3	3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR	1757117-1757148	32	NZ_CP003718	Zymomonas mobilis subsp. mobilis str. CP4 = NRRL B-14023 plasmid pZM1402303, complete sequence	17777-17808	0	1.0
NC_018145_3	3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR	1757117-1757148	32	CP036464	Zymomonas mobilis strain ZM4* plasmid pZM36o, complete sequence	1240-1271	0	1.0
NC_018145_3	3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR	1757117-1757148	32	CP036460	Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 strain ZM4 plasmid pER79ap36, complete sequence	1240-1271	0	1.0
NC_018145_1	1.3|125761|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125761-125791	31	NC_011363	Zymomonas mobilis subsp. mobilis ATCC 10988 plasmid pZMO1, complete sequence	328-358	1	0.968
NC_018145_1	1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125701-125731	31	NC_013784	Zymomonas mobilis subsp. mobilis ZM4 plasmid pZZM401, complete sequence	19257-19287	2	0.935
NC_018145_1	1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125701-125731	31	NZ_CP023686	Zymomonas mobilis subsp. mobilis strain ZM4 substr. 8b plasmid pZM41, complete sequence	40619-40649	2	0.935
NC_018145_1	1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125701-125731	31	NZ_CP023680	Zymomonas mobilis subsp. mobilis strain ZM4 substr. 2032 plasmid pZM36, complete sequence	36255-36285	2	0.935
NC_018145_1	1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125701-125731	31	NZ_CP003712	Zymomonas mobilis subsp. mobilis NRRL B-12526 plasmid pZM1252603, complete sequence	29552-29582	2	0.935
NC_018145_1	1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125701-125731	31	NZ_CP003718	Zymomonas mobilis subsp. mobilis str. CP4 = NRRL B-14023 plasmid pZM1402303, complete sequence	19257-19287	2	0.935
NC_018145_1	1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125701-125731	31	CP036464	Zymomonas mobilis strain ZM4* plasmid pZM36o, complete sequence	36259-36289	2	0.935
NC_018145_1	1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125701-125731	31	CP036460	Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 strain ZM4 plasmid pER79ap36, complete sequence	36254-36284	2	0.935
NC_018145_1	1.3|125761|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125761-125791	31	NC_019019	Zymomonas mobilis plasmid pZMN1-1, complete sequence	328-358	2	0.935
NC_018145_1	1.3|125761|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125761-125791	31	NZ_CP021792	Zymomonas mobilis subsp. mobilis strain NRRL B-1960 plasmid pZMO1960_1A, complete sequence	924-954	2	0.935
NC_018145_1	1.3|125761|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125761-125791	31	NC_019198	Zymomonas mobilis subsp. mobilis NCIMB 11163 plasmid pZMO1A, complete sequence	328-358	2	0.935
NC_018145_1	1.3|125761|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125761-125791	31	NC_019210	Zymomonas mobilis subsp. mobilis plasmid pZMO1B, complete sequence	328-358	2	0.935
NC_018145_1	1.3|125761|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125761-125791	31	AP013397	Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-U-MedDCM-OCT-S25-C46	29814-29844	6	0.806
NC_018145_1	1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125701-125731	31	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	655354-655384	7	0.774
NC_018145_1	1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125701-125731	31	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	2020992-2021022	7	0.774
NC_018145_1	1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125701-125731	31	NZ_CP040722	Rhodococcus pyridinivorans strain YF3 plasmid unnamed3, complete sequence	31248-31278	7	0.774
NC_018145_1	1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125701-125731	31	NZ_CP050953	Rhodococcus sp. DMU1 plasmid unnamed	175019-175049	7	0.774
NC_018145_1	1.3|125761|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR	125761-125791	31	KX889068	Vibrio phage pVa5, complete genome	72714-72744	7	0.774
NC_018145_3	3.2|1756815|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR	1756815-1756846	32	MN693086	Marine virus AFVG_25M299, complete genome	17608-17639	9	0.719
NC_018145_3	3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR	1757117-1757148	32	NC_007949	Polaromonas sp. JS666 plasmid 1, complete sequence	189090-189121	9	0.719
NC_018145_3	3.5|1756996|33|NC_018145|CRISPRCasFinder,CRT,PILER-CR	1756996-1757028	33	NZ_CP053440	Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eF, complete sequence	390717-390749	10	0.697

1. spacer 3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NC_013784 (Zymomonas mobilis subsp. mobilis ZM4 plasmid pZZM401, complete sequence) position: , mismatch: 0, identity: 1.0

gtaaatcagctggaattgtcgctgactggata	CRISPR spacer
gtaaatcagctggaattgtcgctgactggata	Protospacer
********************************

2. spacer 3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023686 (Zymomonas mobilis subsp. mobilis strain ZM4 substr. 8b plasmid pZM41, complete sequence) position: , mismatch: 0, identity: 1.0

gtaaatcagctggaattgtcgctgactggata	CRISPR spacer
gtaaatcagctggaattgtcgctgactggata	Protospacer
********************************

3. spacer 3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023680 (Zymomonas mobilis subsp. mobilis strain ZM4 substr. 2032 plasmid pZM36, complete sequence) position: , mismatch: 0, identity: 1.0

gtaaatcagctggaattgtcgctgactggata	CRISPR spacer
gtaaatcagctggaattgtcgctgactggata	Protospacer
********************************

4. spacer 3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP003712 (Zymomonas mobilis subsp. mobilis NRRL B-12526 plasmid pZM1252603, complete sequence) position: , mismatch: 0, identity: 1.0

gtaaatcagctggaattgtcgctgactggata	CRISPR spacer
gtaaatcagctggaattgtcgctgactggata	Protospacer
********************************

5. spacer 3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP003718 (Zymomonas mobilis subsp. mobilis str. CP4 = NRRL B-14023 plasmid pZM1402303, complete sequence) position: , mismatch: 0, identity: 1.0

gtaaatcagctggaattgtcgctgactggata	CRISPR spacer
gtaaatcagctggaattgtcgctgactggata	Protospacer
********************************

6. spacer 3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to CP036464 (Zymomonas mobilis strain ZM4* plasmid pZM36o, complete sequence) position: , mismatch: 0, identity: 1.0

gtaaatcagctggaattgtcgctgactggata	CRISPR spacer
gtaaatcagctggaattgtcgctgactggata	Protospacer
********************************

7. spacer 3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to CP036460 (Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 strain ZM4 plasmid pER79ap36, complete sequence) position: , mismatch: 0, identity: 1.0

gtaaatcagctggaattgtcgctgactggata	CRISPR spacer
gtaaatcagctggaattgtcgctgactggata	Protospacer
********************************

8. spacer 1.3|125761|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NC_011363 (Zymomonas mobilis subsp. mobilis ATCC 10988 plasmid pZMO1, complete sequence) position: , mismatch: 1, identity: 0.968

aatctgttcaacactatcagcttgcaattta	CRISPR spacer
aatctgctcaacactatcagcttgcaattta	Protospacer
******.************************

9. spacer 1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NC_013784 (Zymomonas mobilis subsp. mobilis ZM4 plasmid pZZM401, complete sequence) position: , mismatch: 2, identity: 0.935

acacgcttgatcttcttctgtggcgcgatgc	CRISPR spacer
atacgcttgatcttcttctatggcgcgatgc	Protospacer
*.*****************.***********

10. spacer 1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023686 (Zymomonas mobilis subsp. mobilis strain ZM4 substr. 8b plasmid pZM41, complete sequence) position: , mismatch: 2, identity: 0.935

acacgcttgatcttcttctgtggcgcgatgc	CRISPR spacer
atacgcttgatcttcttctctggcgcgatgc	Protospacer
*.***************** ***********

11. spacer 1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023680 (Zymomonas mobilis subsp. mobilis strain ZM4 substr. 2032 plasmid pZM36, complete sequence) position: , mismatch: 2, identity: 0.935

acacgcttgatcttcttctgtggcgcgatgc	CRISPR spacer
atacgcttgatcttcttctctggcgcgatgc	Protospacer
*.***************** ***********

12. spacer 1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP003712 (Zymomonas mobilis subsp. mobilis NRRL B-12526 plasmid pZM1252603, complete sequence) position: , mismatch: 2, identity: 0.935

acacgcttgatcttcttctgtggcgcgatgc	CRISPR spacer
atacgcttgatcttcttctatggcgcgatgc	Protospacer
*.*****************.***********

13. spacer 1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP003718 (Zymomonas mobilis subsp. mobilis str. CP4 = NRRL B-14023 plasmid pZM1402303, complete sequence) position: , mismatch: 2, identity: 0.935

acacgcttgatcttcttctgtggcgcgatgc	CRISPR spacer
atacgcttgatcttcttctatggcgcgatgc	Protospacer
*.*****************.***********

14. spacer 1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to CP036464 (Zymomonas mobilis strain ZM4* plasmid pZM36o, complete sequence) position: , mismatch: 2, identity: 0.935

acacgcttgatcttcttctgtggcgcgatgc	CRISPR spacer
atacgcttgatcttcttctctggcgcgatgc	Protospacer
*.***************** ***********

15. spacer 1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to CP036460 (Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 strain ZM4 plasmid pER79ap36, complete sequence) position: , mismatch: 2, identity: 0.935

acacgcttgatcttcttctgtggcgcgatgc	CRISPR spacer
atacgcttgatcttcttctctggcgcgatgc	Protospacer
*.***************** ***********

16. spacer 1.3|125761|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NC_019019 (Zymomonas mobilis plasmid pZMN1-1, complete sequence) position: , mismatch: 2, identity: 0.935

aatctgttcaacactatcagcttgcaattta	CRISPR spacer
aatctgctcaacgctatcagcttgcaattta	Protospacer
******.*****.******************

17. spacer 1.3|125761|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021792 (Zymomonas mobilis subsp. mobilis strain NRRL B-1960 plasmid pZMO1960_1A, complete sequence) position: , mismatch: 2, identity: 0.935

aatctgttcaacactatcagcttgcaattta	CRISPR spacer
aatctgctcaacgctatcagcttgcaattta	Protospacer
******.*****.******************

18. spacer 1.3|125761|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NC_019198 (Zymomonas mobilis subsp. mobilis NCIMB 11163 plasmid pZMO1A, complete sequence) position: , mismatch: 2, identity: 0.935

aatctgttcaacactatcagcttgcaattta	CRISPR spacer
aatctgctcaacgctatcagcttgcaattta	Protospacer
******.*****.******************

19. spacer 1.3|125761|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NC_019210 (Zymomonas mobilis subsp. mobilis plasmid pZMO1B, complete sequence) position: , mismatch: 2, identity: 0.935

aatctgttcaacactatcagcttgcaattta	CRISPR spacer
aatctgctcaacgctatcagcttgcaattta	Protospacer
******.*****.******************

20. spacer 1.3|125761|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to AP013397 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-U-MedDCM-OCT-S25-C46) position: , mismatch: 6, identity: 0.806

aatctgttcaacactatcagct--tgcaattta	CRISPR spacer
aatcttttcaacactatcagctaaagcaaac--	Protospacer
***** ****************   **** .  

21. spacer 1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.774

acacgcttgatcttcttctgtggcgcgatgc	CRISPR spacer
acacgcgtgatcttcttctgtgtgccgcttg	Protospacer
****** ***************   ** *  

22. spacer 1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 7, identity: 0.774

acacgcttgatcttcttctgtggcgcgatgc	CRISPR spacer
acacgcgtgatcttcttctgtgtgccgcttg	Protospacer
****** ***************   ** *  

23. spacer 1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040722 (Rhodococcus pyridinivorans strain YF3 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.774

acacgcttgatcttcttctgtggcgcgatgc-	CRISPR spacer
agccgctcgatcttcttcagtggcgc-ctgtg	Protospacer
*  ****.********** *******  **. 

24. spacer 1.2|125701|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050953 (Rhodococcus sp. DMU1 plasmid unnamed) position: , mismatch: 7, identity: 0.774

acacgcttgatcttcttctgtggcgcgatgc	CRISPR spacer
acgatccggatcttcttgtgtggtgcgatgc	Protospacer
**.  *. ********* *****.*******

25. spacer 1.3|125761|31|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to KX889068 (Vibrio phage pVa5, complete genome) position: , mismatch: 7, identity: 0.774

aatctgttcaacactatcagcttgcaattta	CRISPR spacer
aatctcttcaacagtatcagcttcagctttc	Protospacer
***** ******* *********  . *** 

26. spacer 3.2|1756815|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to MN693086 (Marine virus AFVG_25M299, complete genome) position: , mismatch: 9, identity: 0.719

caagctatagcaaaattggaaaagacaaatgc	CRISPR spacer
aagactatagcaaaatgggaaaatacaaccct	Protospacer
 *..************ ****** **** . .

27. spacer 3.7|1757117|32|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NC_007949 (Polaromonas sp. JS666 plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.719

gtaaatcagctggaattgtcgctgactggata	CRISPR spacer
cttaatgacctggaattgtcgctgacagagcg	Protospacer
 * *** * ***************** *....

28. spacer 3.5|1756996|33|NC_018145|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053440 (Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eF, complete sequence) position: , mismatch: 10, identity: 0.697

gacccgttctgcggcaccatgccgagaagctgt	CRISPR spacer
aggccattctgcggcgccatgccgagagcttcg	Protospacer
.. **.*********.***********. .*  

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	147758 : 160984	9	Thermus_phage(12.5%)	NA	NA
DBSCAN-SWA_2	897285 : 905446	7	Staphylococcus_phage(33.33%)	NA	NA
DBSCAN-SWA_3	977834 : 988318	10	uncultured_virus(14.29%)	terminase	NA
DBSCAN-SWA_4	1091000 : 1153371	52	Paenibacillus_phage(25.0%)	transposase,protease	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_018145|147758:160984|DBSCAN-SWA
TATGACCTCATCTCGCTTCCCGTCTATGACCGAGGAAGATTACCGCGCCTCTTTACGGCTTATCCGAACACCCCGTATCGGGGCTGTAACCTATAACCAATTGATAACCCGATATTCTTCACCCCAAGAAGCCCTAAAAGCCGTGCCGCTTCTGGCTAAAAGGGGCGGCGGCCAAGCGCCGAAAATCGCCTCGGAAAAAACGGTCAATGAAGAAATAGAGCAAGTCAAAACTTTAGGCGCGCGTTATATTTTTCGCCATACGCCTTATTATCCGCCGCTTCTCGATCAATTGGATAATGCCCCTCCGGTTCTCTTGGTGAAAGGGAATCCGCGTTTATTGCAAAAACCGGCGATTGCGATGGTCGGGGCAAGAAATGCTTCGGCCGCCGCCTGCCGTTTTGCCCATGATCTCGGACAAGAATTGGCGAATAACGGCTATCCGGTTATTTCTGGACTGGCACGCGGCATTGATACCGCCGCGCATCAAGGTGCGGGGATAGAGAAAACGATTGCGGTTATTGCGGGGGGTCTCGATAGCTTTTACCCACCCGAAAACAAAGAATTGCAGCAGGCTATTTCTGAAAAAGGCTTGGTCGTCAGTGAAATGCCACCCAAAAGCGAACCAAAAGCCCGCCATTTCCCAGCACGAAACCGGATTATCGCCGGCATTGCCCTTGGCGTTTTGGTTGTCGAAGCCTCCCCTAAATCCGGTTCGCTGATTACCGCCAAATTGGCGACAGAAATCGGGCGGGAAGTCATGGCCATTCCGGGCTTCCCGATGGATGCGCGCAGCCAAGGCTGTAACCAGCTCATCAGGGAAGGCGCAACACTGATCCAAAATAGCGATCAGATTATCGAGGCGGTTTCTGTCATGGCCGCGCTTTTTGAAGAACCCACCGAAAAAAGCCCTCTCGAACCGCATTTTTCTGGCTTGAAAAATGGTCAAATTGCCTATCGTCCTTCTCCGGTTATTGCCGAGGTCGGGGCAAAAGACCGCGAAACTATTCAAAATCTGATTGGTTCAGCCCCTGTCGGGGTAAATGAACTTATCCGGCAATCAGGTCTGGAAAATGCGATAATCCAAACCATCTTATTGGAAATGGAGCTGGCTGGACGGCTCGAAAGTCATGCAGGCGGACGGATAAGTCTGCTTTTTTGAATGATTTTTTGTTGCTTTCAACTCTGCCCCGCGAATACAGAATAGATCAACCCTTGTCTGTTTATCATTTTTTCAAAGGGATTTTCCCCTTTGATAACGAAAAAAAAGGCTCACTCTCCGCCGTAAATTGCGCGGAATGGTCAGGAGTATCATGAAACTCGTTGTTGTCGAATCACCGGCCAAGGCCAAAACTATCGAAAAATATCTTGGGTCGGGCTATCAGGTGCTGGCCTCTTATGGTCATATCCGCGATCTTCCCTCCAAGGATGGCTCTGTTAATCCCGACAACGGCTTTTCCATGGTCTGGCAAAATTACCCTGACAAAGCCCACCGCCTGAAAGCGATTGAAGACGCGGTAAAAGAGTCTGACAGCCTCATTCTCGCGACTGACCCTGACCGCGAAGGGGAAGCGATCAGCTGGCATATTCTCGAATTGTTAAAGACCAAAAAACTGTTACCCGATGATGTCGAACGGGTGACCTTTAATGCTATTACCAAAGCGGCTGTTACCGATGCTATGGCGCATCCTCGCCAACTCGATAATGATTTAATCAATGCCTATCTGGCGCGTCGGGCTTTGGATTATCTCGTCGGTTTCACGCTCTCTCCGATTTTATGGCGGAAATTACCGGGCGCAAAATCAGCCGGACGGGTGCAATCAGTCGCCTTACGGCTGGTGGTTGACCGTGAGCAAGAAATAGAAGGCTTTAAACCGCAAGAATATTGGTCGGTAGAAGCCGATATGGAAGCCGACAGTATCGGCTTTACTTCGCGGCTTATCCAATGGCACGGCCAAAAACTCGAAAAGCTGTCTATCGCAGATAAGACGCAGGCCGAGGCCGCCAAATCCGATGTTGAATCCGGTCATTTCACGGTTTCCAATGTCGAAACCAAACCGGTTTCCCGTAATCCACAACCACCTTTTACGACATCGACATTGCAACAGGAGGCCGCCCGTAAATTGGGTTTTGCGGCCAGCCATACGATGCGTCTCGCTCAAAGCCTTTATGAAGAAGGGCTTATTACCTATATGCGGACGGACGGGGTTCAGATGGATGAAAGCGCGATTGTCGCGGCTCGAAAAACCATCACCCAACGCTATGACGGCGGCTTTGTGCCGGACAAGCCAAGACAATATCAGGTCAAAGCTAAAAATGCCCAAGAAGCCCATGAGGCTATTCGCCCAACCGATTTTTCGCGCGATAAAGCGGCCAGCGGCGATCATGCCCGTCTTTATGAACTGATCTGGAAACGCGCCCTTGCCAGCCAAATGGCCTCAGCCAAATTGGAACGGACAACGGTCGATTTAACCGATGGCACGGGACAAAATGTCTTGCGGGTCACGGGGCAGGTCGTTTTATTCTCTGGCTTTCTTACGCTTTATGAAGAAAGCGCTGACGATAACGCCAATGACCGCGATGGCAAAGAAGGCCGCGCCCGTTTGCCTTTATTACGGGCAGGCGATGCACCCTTGAAAAAAGAAGTCAGGGCAGATCAACATTTCACCCAGCCGCCGCCCCGTTATTCGGAAGCGAGCTTGGTCAAAAAAATGGAAGATTTGGGAATCGGCCGCCCATCCACTTACGCTTCGGTTATTCAGGTTCTAAAAGACCGCGCCTATGTCACACTGGAACGCAACCGCTTCATTCCCAGCGAAGCCGGACGTTTGCTGACGGCCTTTCTCGAACGTTTCTTCGAACGTTATGTCAGCTATGACTTTACCGCGGGCTTGGAAGACAGCCTTGACGAAATTTCCGGCGGTCGGGCTGACTGGCAAAAAGTCCTTGATGCTTTCTGGCATGACTTCAAACCCAAAACCGCCGAAGTCATGGAACAACAGCCCTCGGCTATCACCGCAGAATTAGACAAATTTCTTGAACCTTGGCTTTTCCCTGACAAGGGCGACGGCCATGATCCCCGTGAATGTCCCTCCTGTCATACGGGTCGTTTGGCGTTAAAAGGGGGACGCTTCGGTGCCTTTATTGCCTGCTCGAATTATCCCGAATGTAAATATACCCGTGGCTTTGGGCAGGGTGAAGACGGCGTTGACGATAACGAACCCGTCCTGCTCGGTTATATGCCCGAAAACTCGGATGATGACGGCTATATGGCGTTTTCAGACCAAGGGGATATTTCACCCACTAATACCGCTTCAGCCTCTGAAACGGGCGTTACTGACGGCGGTGCCGCGGCTAATACGGCCTTTTCTGGCAAGGGGAATAGCGCATCCCATACAGACAGGGATGACTTACCCTTCGATCCTGACGAACCCGCCTCTTCAACCGGAAATATCACCTCCTCACAATCCCGCATGGCAGGTGGCGAAACGACGTCTTCTGGCAATAGCAGGGATTCCTCGGCTCATGGGGTTTCGACCGCTGCCGGAATCGATGCTGAAAGCCAAGCCGGTATCAGCAATCAGGCGCTTGCCGGTAAAAATAATGTAGGTCGTACCGCCGTCTCCGACAACAAGGGAAATAACAGCAGCGGCACAATCGCTGCGGCTCACAAAGGCGGTTCTACTGACGATAATGCGACAGCCTCCGATCATGATGGGGATATTGGCAGCGGGGCATCTTCTGCCGGTCAGGATGTCGATAATACGCTTCTATCTCATCGTAATGGAGACATTGATAGCCGCGCGATTCCTGCGGCTCACAACGGCAGTTCTACCGATCAGAATGCCAATGCCAGTGATGCGGCTGTATACAACGCCGATAACCATGCGCTTTCTCATGATCGCAATTCTGACGATGCCTCTGTCTCTAACAGTGATAAAAAGACTGATAGCAAGGCCGTTTCTACCGGCCATGATGTCGACAATGCCATAACGTCTGATAACAGCCCTTCAGATAATGTCGCCCATCTGGCTAGCATGCCTTCTTCTGCAACCTCCTCGGTAAAAGTTGCTCTGGAAACAGAAAACAATGATACGGCCGCTAGCAAAGCGGATGAACAAGCCAAAGAGGAAGAAGAAGCCAGAAAGGCGAGGGCAGTTACACGCCGGACAGGTCGTTTCGGGCCCTATATCCAGCTAGGCGAAGGCAAAGAAGCTAAACGGGTCTCTGTCCCCCGCGATGTCAATCCAAGGGAGGTTGATTTCTCATTAGCCAGCCGCCTCTTAGCACTGCCTCGCGAAATTGGGCTTCATCCCGAAAGCGGCAAAATGATTATTGCCGGAACCGGACGCTATGGGCCCTATCTCAATTGTGACGGCAAATATGCCCGCCTGTCTTCCACGGAAGAGCTGTTGGACATTGACATCGATCGGGCTGTTGTAAAACTGGCCGAAGCCGCCCAAAATAAGGGGCGCACCGGTACGACATTATCCCGCGAACCTTTGAAGGTTTTTGGCGATAGCCCTGTTACCGAAAAGCCAGTTCAACTGATGAATGGCCGCTACGGGCCCTATGTCACCGATGGCGAAACCAATGCCTCTTTACCGAAAGACACAACCCCCGAAAGCCTAACTTTCGAAGAGGCTTTGGCGTTATTAGAAGCCCGCTCCAAAATGCCGAAAAAGAAGAAAACCAAAAAGGTAGCAGCCAAGAAACCTGCCGCCAAGAAGACCACCACAAAAAAAGCCGCCCCTAAAAAGGCGACAACAAAAACTGCAAACCTAAAATCGGCCACTACCGACAGCGCGACTTCAGAAGATGGCGATGCCACCCCTGCCAAGTCACCCGCCAAAAAAGCTGCTGCGAAAAAAACAACGGCAAAGAAGCCTGCTTCAAAAAGCGCGACTAAAAAAACTCCGGCCAGCAAAACGACCGCAGCGAAAAAGACTTCTAAAGCCGCCCCCAAAGACGAAGTGGCCGAATAAAAACAAAAACGGGATAGCCATGGCTATCCCGTTTCTACTTTACATCCTTAGCTTTTTTAAACCCCAAGCTTCCCAGCCTCACTTGCATCCGCCCGACTATCTATTCCACTCAAGGCCGACAACGGATTCAATCACAACCTATCTTTACAGATCCTCTAATCTCAATCTGCAAAGCGATTATTAAAGGCGATCCAAAAACTCGCGTCGATAATATCAAACACCCACTTCGGAAAGCAGCTATGTCACTCTCGAGAAGGCATCTGCAAAGATAGACAGAGCTTTCTATTCATCTATCATATATTCCAGACAACCTTGGCTCGTGCGATGACTCTTATTCCTTTAGTTATCGTCTTATCATACGCTTACGATCTAATTTATCCAATCAACCAAAAGCTATTCTGCGCTATGCTTGCAGCGACAATTCGGGTCTTTGCTCAAAGATACAGTTCTGAAACGAAAATCTTTGGCATCAATCAGCAATAATTTGTTGCCGCTCTCGGAACCAAATCCTGTAATTAAACGGATAGTCTCAATCGCAGCTAAACTTCCGATAGTTCCAGTCAATGCACCGAGGACACCTTGCGCTGAACAAGTCATCTCCGGTTCTCCCGGATCATCACCGACAAAACAGCGATAACAAGGTTTACTTGCTTCATATCCCTTGAAAACGGCTAACTGCGCCTCAAAACGAATAACAGCAGCTGACACTAGAGGAATTTTTAACTCTGTTGCCACATCGCTGACAACCAAGCGGGTTCCAAAATTATCACTGCCATCCACAATAATGTCAGCCTGACCAATCAGCTTCTTAGCATTCTCTGCATCCAGCTTCTGGTCATAAGGCAATACTTTAACATCAGGATTCAGACGTTGGACAACATTAGCAGCCATAGCTACTTTATGTGCTCCGATATCACGGGTCGCAAAAAGTGTTTGTCTCTGTAAATTCGAGAGAGAAACCTCGTCATTATCAACAATAGTAAGACGACCGACACCAGCAGCAGCCAAATATTGAATAACCGGAGAACCTATTCCTCCAGCACCAACAATTGCGACATGAGCTGATAAGAGTTTTTTTTGTCCCTTGCCGCCGATTTCAGGTAAAACAATATGACGGGCATAACGATCTAGCTGATTATCAGTAAGTATCATATTCCGGTCGATCCAAATCCGTTATGGCCACGCTGGGTATCATCTAAATCAGTGACCTCACAAAATACAGCTTGCGTTACTGAAGCCAATATCAGCTGAGCAATACGATCACCTCTTTTAATTTCAAAAGCTTCGTTGCCCAAATTAATAAGAAGAATTTTAACTTCGCCACGATAATCAGAATCAATAGTTCCAGGAGCATTAGGGCAAGCTATACCATGCTTTAACGCTAACCCCGATCTAGCACGAACCTGAATTTCATATCCGTTAGGAATAGCTACAGCGAAACCAGTTTTAACCGGATAACGTTGCATCGGTTGCAAAATCACGTCTTCTGCTGACACTACATCCATTCCAGCAGCGCCCTCACTAGCATAAGAAGGGAAGGGGAGGTTTGCGCCATGGGGTAGGCGTTTTATTTCAAGTTTTATTTTCATTAAATGATATCCCTTTATGCCAAGCAAAATTTTATTTTGATATAATTGATGATGGGTGTTCATTTATAAGATTAAAGTAATCGGCTATTTTACTCGCTAACCGAGAAGCAACCTCTTTTTTGGACAAAAGAGGCCAATTTTCTATACCTGCATGGCTGGCAATGAAGATTTTATTATAGTCTCCACCCATTGCCGAGGGGGCATCTTCACTCTCAATAACAGGATTGGCTATTATCCAGTCACAACCTTTTTGTTGTAACTTTACTTTTGCATTTTCTAATAGATTTTCTGATTCTGCAGCGAAACCAACAACTAAAGAAGGACGGTCTATTTTCCTGTGAGATATATTCGATAAGATATCTGGATTTTCTATCGGTATAAGGTCAGGTTCTGATCTACCTTTTTTATATTTTGATGGAGAATAATTGAACCTCCAGTCAACAACAGCCGCTGTAAAAATAGCACCATCTGCTGGGAGAGCATTTTCGACAGCTTTTTCCATTTCAATAGCCGTTTCAACATTCACGCGTTCTACTCTGTCTGGGGTGTTTTGATAAACAGGCCCCGTAACAAGTGTAACTTTTGCACCTAATTTTTGTAAGGCTTCAGCGATCGCGAAACCCTGTTTTCCAGAAGAGCGATTGGCTAGGTAGCGGACAGGATCAATTGGTTCATGTGTTGGTCCTGCTGTCACAATAAAATGTCTATTTTTTAAAAATTGATGATTTTGTTTTTCTGCAAAGAGAGACTCTGCAGATAAAAGAATGTCTTCTGGTGCTGCTAATCGTCCAATTCCTGTTTCGCCACAAGCCATAGCCCCAGCTTCTGGATCAACAAAAGATATACCATCAGATTTTAGTTGATGAATATTCCGTTGAGTTGCTGAGTGATGCCACATGCGATGATTCATTGCAGGCGCGACTAAGATTGGACTATCCGCTGCAAGAACTACAGTAGAAGCCAAGTCGTTAGCCAATCCATGAGCCATTTTTGAAATAAAGTCAGCTGATGCAGGTGCGACAATAATCATATCGGCTTCACGGGCTAGACGAATATGACGAATTGAAGCCTCTTCGCTTTCATCCCACATATCCTGCGCTACTGGATTGCCTGATAAACTAGCAAGAGCAAGTGGCGTTATAAAATTCGCTCCACCTTTTGTGACGAGACAGCGGATGTCAGCTTTTTTCTTCCTGAATAAGCGGATTATATCTGGGGCTTTGATAGCTGCAATACTACCAGAAATAACTAACAGGATTCGCTTTCCATTTAAAAAAGAAGACATAGATTATCTCGATTTGGAGGAGAGAATTAAAAAAAATGATAATGGCCCAGAATTATCCCGATAATAAACGCGCTAAGGATAAAGACAGGCAAATAATGTTTTGTAGCAGCAGATTTAATCGAATCCTTATTCGCTACAGGATAGAGCTGTTCCTCTATGGTGAGAGGCGGATAATATTGATCTATCCGATCAATGAGTTCTGGTAACCGCTTAATGCTTTGAAGTGTTTTATAAAATTCTTCAGCTATTTTAGCTTCGGGTCCCAACTCTGAGCGTAACCATTCTCTTACAAAAGGCTCAGCTGTATCCCATAAATTAATATCAGGATATAAAGAGGTAGCCACTCCTTCAACTACAACCATCGTTTTTTGCAAAAGTAAAAGATGTGGCTGGGTCTGCATCTCAAATTCACGGGTTATAGAAAATAACCCGTCCAGCATATGACTGATAGAAATACCGCGAACAGATAATCCTCTGATAGGTTCTCCAATAGTCCGCAAAGCAGTCGTGAATTCTGCTATGTCATGGTGAGAGGGAACATAGCCTGCCTCGAAATGAATTTCTGCTATTCTGGAATAGTTACCTGTAATAAGGCCGTATAATATTTCAGCTAACCAGCGCCGTGCTTTTTTGTCGATCCGACCCATAATACCAAAATCAACAACAGCAAGAGATCCATCTTTTAATGCAAATAAATTTCCGTGATGGAGGTCAGCATGGAAAAAACCATCAGCTATAGCCTGCCTTAAGAAACTGCGAACAAGCCGAGTTGCCAAAGATTTTAGATCATATCCGGCCTCTTGCAATTTTTGATGATCTGAAAGCTTAATGCCATCAATCCATTGCATTACCATCATAGACTGGGATGTCCGATTCCAGTCTATTACAGGGACTTTAAAACCGGGAACCGCTTCCATATTTTCCGCTAACTCCGAGGCAGACGCAGCTTCTCTCCTTAAATCAAGCTCACGTATTGTCCATTGGCGGAAAGTTTTTACAACTAATTTAGGACGTAGGCGGATAAACTCATCATTTAATGATTCTATTTTCGTTGCAGCCCATTCATATGTTTCTGTAGCCTTTCGAAAAGCCTGCTTTATTCCTGGACGCAGTACTTTTACCGCGACTGTAACGCCATCAAGTGTTTCTGCCTGATACACTTGAGCAATAGATGCCGAACCAATAGGAATTTCGTTAAAAAAACGGAAGGATTTCTCAATAGGACATCCTAAGGCATTTTCGATAACTATACGAATATCTTTAAAAGGCAAAGGCGGTACAGAGTCTTGTAAATATGCCAATTGAGCGGCTGTTTCTTCTCCGATTAGATCTGGTCGTGTTGCTAAAGTCTGACCAAATTTGATTGCAGCTGGTCCTAAGGCGACAAAAGCGCCTGTATAATCGGGTGGGTTTGGAACTCGATAGCCGATCCTAATTAATCTTATTATCAAACGAAGGGATAACGGAACAATTGTAGATTTCTCTACCGTTTTTAAAACGCCATGTTTCGATAATATTCGGCTCCAGCGGAATAAACGCCAAAGATGAACAACGGCTAATGTCATTAATTAGACTTTCCAACCGCTATGTATAGCCACTAAACCACCTAAAATTGGCCTTGCTCGTATTTGGACAAAACCAGCGGATTTAATCATATCAGAAAATTTTTCTATGTTAGGGAATCTTTCGATAGATTCGATAAGATAGCGATAACTGTCCTCATCATTGGCTAATAGCTGACCAATTTTAGGTACGATATGTGTTGAATACATTTTATAAAGATTAGAAAATCCTGACCATTTCGTCTGGGAAAATTCCATGCAAAAGAAACGTCCCCCTACTTTTAAAACACGCCACGCTTCGTCTAGTGCTTTTTGTATATGTGTTACGTTTCTAATACCGAAAGCTATAGTGTAAGCGTCGAAAACATTATCATTAAATGATAATGTTTCAGCATTTTCTTCTTTCCATGTAAGATTTTCTATCGAGCGGGCTGTAGCTCTCTTTTTTCCGACTTCAAGCATAGCTGGATTGATATCTGCAATCGTGACATTTGTACCGTATTTTGCCAATCGAAAGGCAATATCTCCGGTGCCGCCCGCCATATCTAGAATATGTTCACTGGCCTTCGGTTGAACCAGACGAACAAAATCATCTTTCCATAACCGATGGAGTCCACCTGACATAGCATCATTCATTAAATCATAGCGCGATGCTACACGACGAAAGACATCGCCAACAAGATGTGTTTTTTCTTGAGGCGAGACGTCTGAAAAACCGAAAGAAACTTTTTCCATATGAAAAAGTTTTAATGCTAATCAAAAGAACATTGAAGCGTAAAAAACTTTATGCTGCTGTTTTTTCTTATTTTGAGTGTTGAAAATGGAGCGGATGAAGGGAATCGAACCCTCGTCTTAAGCTTGGGAAGCTCCTGCTCTACCATTGAGCTACACCCGCTAGGGTTATTTTGATCTTGAAATCAAAGGCTCTTTGCCACAACTAATATCTTTTGGTCAATGTTATGTTTACACAAAAACAGAATACTTGAATAATTTTGTCTATTAACCATTTCTGGATATATTCGACAATTTAAACGGAAGATCCTGTTGCCAGAGCTACCAGAAGTTGAAACTACCGTTCGTGGACTATCTGAAGTCCTGATGGGTGAAAAAATTATAGATGTGAAAGTGCGCCGGGTATCTTTAAGACGGCCAATACCTTCTGATATTCAAGAAAGGCTGATGGGATCAACTATCATTTCTCTTAGTCGACGCGCAAAATATGGCATCATTGTCAATAATCGGGATGATGCGTTAATTTTCCATCTTGGGATGTCCGGTCGATGGAAAATAAATCCTGAAAATTTTGAGAAACACGACCATTTCGTTCTTCAAACAAAAAATAATTTTATAGTTTCACTTTATGATCCGCGTCGCTTTGGCTCTCTTGATTTAGTAAAAAAAAATCAATTGTTAGAATGGTCTTATTTTAGAAATCTCGGGCCAGAACCTTTAACTGGGAATTTTAATCCAGAATATTTACAGAAGAAGTTATTCTCTTCTTCTGCTCCCATAAAAAAAATATTATTAGATCAAAAAGTAGTTGCTGGCATTGGTAATATTTATGCTTGTGAGGCTTTGCACCAAGCCAAGATACATCCTCAACGGCCTAGCAAAAATTTAAATTTTGATGAAATAACTTCACTTGTTTTTTCTATCAAAAATATTTTGCAAAAGGCCATAGCTGAGGGCGGGTCAACCTTAAAAGACTATGCACGCCCTAATGGAGAGCTAGGTTATTTTTCGAATAAATTCAAAGTATACGGCAAAGAAGGTGAACAATGCAAATGTGGTCATACGATCGAGCGTTACACTCTAGGTGGCCGTTCAACTTTTTTGTGTTCTTCATGTCAAAAATAACCATACAATATTTACATATTTTGTTTATTTATATTATTTGATGCAAGTAATTTATTAACTTCTTTTGTCTTATTATTTAACCGGACAGCATTATCGCCGGGCATTCCTGGAAATTTAGGCCACATCCCTTGCGCCATCGCATTCAAACTTTGAGAAGATGAAGATGCTTTTTGCTGATATATCCAATAATTACGCAATACAGTCGCAACATAAGCGCGGGTTTCTGCATATGGTATAGATTCAATAAAAAGCAGTGGGTCGCCATGATCACGGTCTTTCCAACGGGGCAAGGCAGCTGGACCCGCATTATAGGCTGCAATGACTTTGGGCAACAACCCGCCTGTGTAGCTCGTATCCCGTAGCCATTCGATATAGGCTTGACCATATTCAAAGCTGATAGTTGGTTTATCAAGATCTTCTATATCAATATTTGTAGCATGTTGTTTAGCGACCAAACGAGCTGTTGCAGGTGTAATTTGCATAACGCCTCGCGCACCTTTGTTGCTAACGGCTCGGCTACGGAACTGGGATTCTTGTAAGGCATGTGCATAAACAAGATAGGGATCTACATGCCAACCGCTTGCAGGAGCCCAATTTGGAGAAGGATAACGTGCATCAACATCTGCAGAGAAACCCGCGGGACCATGATGGGCTAACCACAATTGTGCCTCTGGCAAACGAAGATAAGATGCTAAATGAATTAAATTGTTATGGTCTTTAGGGTCACCTAGTCGTGCTTGGTGTTTTAAAGTTTCACTGGCAAGCTGATATTCGCCAATTTGGTTCAACGCAATGGCTATTCTGATATTAGGCTGTGTTGTCAAACATTTTAGCTCATCTTCAGATAAGGCGACAGGTCGAACAGAGGACTTAACAGTTTTTCCTAGGGCTTTTTCTGCCAAGAGACCATAAAAAGTTTCTGGCATGTGACTAGCTGAACGTAATAAATTTTGAGTATATTCAGGGTGCCCTGATGCCATCGCGGCTCTGGCTTCCCAGAATAGACCTGCAGCCTTCATTTCTTTATTTTCGCTATAGGATGCAACGCGAGAAAAAGCCTGCATAGCCGCTGAAAAATCTTCTTTTTGCCAATCGGCTAAGCCTTCAACCCAGCTTGCATCAGTTGTCCAGCGCCCAGTGCCATTTTCGGCCTGAACGGCTAAGCGGCGCGCGGCATCATCATTACCATTTAAATAGTAACTCCATGCAATACGCTGAGCCCATTCGGTTTTGATGTCATCAGATAAATTTTGTTGAGAATCTTGAAATAAATTTTCAGCCTGATCAGAAGCATCGGCTTTTATTAAAGGCAGTGCTTTGGTTTCAAAGACCATAGCTGAACGGTTTGTAGCATTGTGGTGATTAACAGGCCTTTGTGGCGCGCCTGATAAAAAGAATAAATTATTTTTTTCTGGCAGTGGTGGAAGTGTTTTTACACCGTGGTTGTAAGCAAGACGTACCAAAGCCTCACCCTGCGGTAAGTAAGGTGACTTCTGAATTAAATTGATAATATCATCTGGGCTGACTTTAGGTGAATTTTTTGCCAAATAAAGTTCAGCTGTTACAAAATCCGTTAGTAGGCCGTCTGGATTCGAAGATATCCATTGCTGTGCAGCTTGCCAACCGCCATGGCGTATGGCCAAAAGACAGTCCTTATATCCCTGTATCTCTCGTGGAGATAAAACTTCTTTTACATTATCTATTGGTACCACACGGGACACAACAACTTGTGAAAAATCGGTTTCGCTATTTTCTAATGCAATATCATCATCAGAAAGAAAACCAGGTTCAGTAACAGGATTTTTATTTGTTACTGTTGCTGCAAATGCTGATGGTGTAGGAGAGAATAACAAAAAAGACATCGCCAAACTACAGGCTGTTTTAAAAGACCGTTTCTTCTTATAAGAAAGAAGATTGATATTGCCTTTATTCGTCTGCGGTTGTCTTTTCAT

Protein sequences of DBSCAN-SWA_1

>NC_018145|147758:160984|159043_160984_-|WP_014848247.1|DBSCAN-SWA
MKRQPQTNKGNINLLSYKKKRSFKTACSLAMSFLLFSPTPSAFAATVTNKNPVTEPGFLSDDDIALENSETDFSQVVVSRVVPIDNVKEVLSPREIQGYKDCLLAIRHGGWQAAQQWISSNPDGLLTDFVTAELYLAKNSPKVSPDDIINLIQKSPYLPQGEALVRLAYNHGVKTLPPLPEKNNLFFLSGAPQRPVNHHNATNRSAMVFETKALPLIKADASDQAENLFQDSQQNLSDDIKTEWAQRIAWSYYLNGNDDAARRLAVQAENGTGRWTTDASWVEGLADWQKEDFSAAMQAFSRVASYSENKEMKAAGLFWEARAAMASGHPEYTQNLLRSASHMPETFYGLLAEKALGKTVKSSVRPVALSEDELKCLTTQPNIRIAIALNQIGEYQLASETLKHQARLGDPKDHNNLIHLASYLRLPEAQLWLAHHGPAGFSADVDARYPSPNWAPASGWHVDPYLVYAHALQESQFRSRAVSNKGARGVMQITPATARLVAKQHATNIDIEDLDKPTISFEYGQAYIEWLRDTSYTGGLLPKVIAAYNAGPAALPRWKDRDHGDPLLFIESIPYAETRAYVATVLRNYWIYQQKASSSSQSLNAMAQGMWPKFPGMPGDNAVRLNNKTKEVNKLLASNNINKQNM
>NC_018145|147758:160984|158219_159032_+|WP_014848246.1|DBSCAN-SWA
MPELPEVETTVRGLSEVLMGEKIIDVKVRRVSLRRPIPSDIQERLMGSTIISLSRRAKYGIIVNNRDDALIFHLGMSGRWKINPENFEKHDHFVLQTKNNFIVSLYDPRRFGSLDLVKKNQLLEWSYFRNLGPEPLTGNFNPEYLQKKLFSSSAPIKKILLDQKVVAGIGNIYACEALHQAKIHPQRPSKNLNFDEITSLVFSIKNILQKAIAEGGSTLKDYARPNGELGYFSNKFKVYGKEGEQCKCGHTIERYTLGGRSTFLCSSCQK
>NC_018145|147758:160984|149067_152739_+|WP_014848241.1|DBSCAN-SWA
MKLVVVESPAKAKTIEKYLGSGYQVLASYGHIRDLPSKDGSVNPDNGFSMVWQNYPDKAHRLKAIEDAVKESDSLILATDPDREGEAISWHILELLKTKKLLPDDVERVTFNAITKAAVTDAMAHPRQLDNDLINAYLARRALDYLVGFTLSPILWRKLPGAKSAGRVQSVALRLVVDREQEIEGFKPQEYWSVEADMEADSIGFTSRLIQWHGQKLEKLSIADKTQAEAAKSDVESGHFTVSNVETKPVSRNPQPPFTTSTLQQEAARKLGFAASHTMRLAQSLYEEGLITYMRTDGVQMDESAIVAARKTITQRYDGGFVPDKPRQYQVKAKNAQEAHEAIRPTDFSRDKAASGDHARLYELIWKRALASQMASAKLERTTVDLTDGTGQNVLRVTGQVVLFSGFLTLYEESADDNANDRDGKEGRARLPLLRAGDAPLKKEVRADQHFTQPPPRYSEASLVKKMEDLGIGRPSTYASVIQVLKDRAYVTLERNRFIPSEAGRLLTAFLERFFERYVSYDFTAGLEDSLDEISGGRADWQKVLDAFWHDFKPKTAEVMEQQPSAITAELDKFLEPWLFPDKGDGHDPRECPSCHTGRLALKGGRFGAFIACSNYPECKYTRGFGQGEDGVDDNEPVLLGYMPENSDDDGYMAFSDQGDISPTNTASASETGVTDGGAAANTAFSGKGNSASHTDRDDLPFDPDEPASSTGNITSSQSRMAGGETTSSGNSRDSSAHGVSTAAGIDAESQAGISNQALAGKNNVGRTAVSDNKGNNSSGTIAAAHKGGSTDDNATASDHDGDIGSGASSAGQDVDNTLLSHRNGDIDSRAIPAAHNGSSTDQNANASDAAVYNADNHALSHDRNSDDASVSNSDKKTDSKAVSTGHDVDNAITSDNSPSDNVAHLASMPSSATSSVKVALETENNDTAASKADEQAKEEEEARKARAVTRRTGRFGPYIQLGEGKEAKRVSVPRDVNPREVDFSLASRLLALPREIGLHPESGKMIIAGTGRYGPYLNCDGKYARLSSTEELLDIDIDRAVVKLAEAAQNKGRTGTTLSREPLKVFGDSPVTEKPVQLMNGRYGPYVTDGETNASLPKDTTPESLTFEEALALLEARSKMPKKKKTKKVAAKKPAAKKTTTKKAAPKKATTKTANLKSATTDSATSEDGDATPAKSPAKKAAAKKTTAKKPASKSATKKTPASKTTAAKKTSKAAPKDEVAE
>NC_018145|147758:160984|155639_157178_-|WP_014848244.1|DBSCAN-SWA
MTLAVVHLWRLFRWSRILSKHGVLKTVEKSTIVPLSLRLIIRLIRIGYRVPNPPDYTGAFVALGPAAIKFGQTLATRPDLIGEETAAQLAYLQDSVPPLPFKDIRIVIENALGCPIEKSFRFFNEIPIGSASIAQVYQAETLDGVTVAVKVLRPGIKQAFRKATETYEWAATKIESLNDEFIRLRPKLVVKTFRQWTIRELDLRREAASASELAENMEAVPGFKVPVIDWNRTSQSMMVMQWIDGIKLSDHQKLQEAGYDLKSLATRLVRSFLRQAIADGFFHADLHHGNLFALKDGSLAVVDFGIMGRIDKKARRWLAEILYGLITGNYSRIAEIHFEAGYVPSHHDIAEFTTALRTIGEPIRGLSVRGISISHMLDGLFSITREFEMQTQPHLLLLQKTMVVVEGVATSLYPDINLWDTAEPFVREWLRSELGPEAKIAEEFYKTLQSIKRLPELIDRIDQYYPPLTIEEQLYPVANKDSIKSAATKHYLPVFILSAFIIGIILGHYHFF
>NC_018145|147758:160984|147758_148916_+|WP_014848240.1|DBSCAN-SWA
MTSSRFPSMTEEDYRASLRLIRTPRIGAVTYNQLITRYSSPQEALKAVPLLAKRGGGQAPKIASEKTVNEEIEQVKTLGARYIFRHTPYYPPLLDQLDNAPPVLLVKGNPRLLQKPAIAMVGARNASAAACRFAHDLGQELANNGYPVISGLARGIDTAAHQGAGIEKTIAVIAGGLDSFYPPENKELQQAISEKGLVVSEMPPKSEPKARHFPARNRIIAGIALGVLVVEASPKSGSLITAKLATEIGREVMAIPGFPMDARSQGCNQLIREGATLIQNSDQIIEAVSVMAALFEEPTEKSPLEPHFSGLKNGQIAYRPSPVIAEVGAKDRETIQNLIGSAPVGVNELIRQSGLENAIIQTILLEMELAGRLESHAGGRISLLF
>NC_018145|147758:160984|153132_153891_-|WP_014848242.1|DBSCAN-SWA
MILTDNQLDRYARHIVLPEIGGKGQKKLLSAHVAIVGAGGIGSPVIQYLAAAGVGRLTIVDNDEVSLSNLQRQTLFATRDIGAHKVAMAANVVQRLNPDVKVLPYDQKLDAENAKKLIGQADIIVDGSDNFGTRLVVSDVATELKIPLVSAAVIRFEAQLAVFKGYEASKPCYRCFVGDDPGEPEMTCSAQGVLGALTGTIGSLAAIETIRLITGFGSESGNKLLLIDAKDFRFRTVSLSKDPNCRCKHSAE
>NC_018145|147758:160984|154359_155613_-|WP_014848243.1|DBSCAN-SWA
MSSFLNGKRILLVISGSIAAIKAPDIIRLFRKKKADIRCLVTKGGANFITPLALASLSGNPVAQDMWDESEEASIRHIRLAREADMIIVAPASADFISKMAHGLANDLASTVVLAADSPILVAPAMNHRMWHHSATQRNIHQLKSDGISFVDPEAGAMACGETGIGRLAAPEDILLSAESLFAEKQNHQFLKNRHFIVTAGPTHEPIDPVRYLANRSSGKQGFAIAEALQKLGAKVTLVTGPVYQNTPDRVERVNVETAIEMEKAVENALPADGAIFTAAVVDWRFNYSPSKYKKGRSEPDLIPIENPDILSNISHRKIDRPSLVVGFAAESENLLENAKVKLQQKGCDWIIANPVIESEDAPSAMGGDYNKIFIASHAGIENWPLLSKKEVASRLASKIADYFNLINEHPSSIISK
>NC_018145|147758:160984|157181_157910_-|WP_014848245.1|DBSCAN-SWA
MEKVSFGFSDVSPQEKTHLVGDVFRRVASRYDLMNDAMSGGLHRLWKDDFVRLVQPKASEHILDMAGGTGDIAFRLAKYGTNVTIADINPAMLEVGKKRATARSIENLTWKEENAETLSFNDNVFDAYTIAFGIRNVTHIQKALDEAWRVLKVGGRFFCMEFSQTKWSGFSNLYKMYSTHIVPKIGQLLANDEDSYRYLIESIERFPNIEKFSDMIKSAGFVQIRARPILGGLVAIHSGWKV
>NC_018145|147758:160984|153887_154328_-|WP_014500349.1|DBSCAN-SWA
MKIKLEIKRLPHGANLPFPSYASEGAAGMDVVSAEDVILQPMQRYPVKTGFAVAIPNGYEIQVRARSGLALKHGIACPNAPGTIDSDYRGEVKILLINLGNEAFEIKRGDRIAQLILASVTQAVFCEVTDLDDTQRGHNGFGSTGI

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014848240.1|147758_148916_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	1.6e-28	38.1
WP_014848241.1|149067_152739_+	type I DNA topoisomerase	A0A0G2Y787	Acanthamoeba_polyphaga_mimivirus	2.7e-93	35.6
WP_014848242.1|153132_153891_-	HesA/MoeB/ThiF family protein	A0A1V0SCZ9	Indivirus	3.7e-13	31.3
WP_014500349.1|153887_154328_-	dUTP diphosphatase	A0A2L1IVN2	Streptomyces_phage	1.2e-32	51.0
WP_014848243.1|154359_155613_-	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	1.5e-43	31.5
WP_014848244.1|155639_157178_-	2-polyprenylphenol 6-hydroxylase	E5ES62	Bathycoccus_sp._RCC1105_virus	2.7e-31	26.5
WP_014848245.1|157181_157910_-	bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE	NA	NA	NA	NA
WP_014848246.1|158219_159032_+	bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase	G3MA33	Bacillus_virus	8.8e-29	32.7
WP_014848247.1|159043_160984_-	lytic transglycosylase domain-containing protein	K4NWI2	Pseudomonas_phage	1.7e-09	28.6

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_018145|897285:905446|DBSCAN-SWA
GCTATTCAGGATCAACCATCAGCGGCAAGGTTACAATAAAGCATGTTCCCTTTCCGGGAGTGCTTCTACAGTCGATATGGCCATGATGCCGCAAAATAACCTTATTAACGAAGACCAGACCTAAACCGATACCTGAAATTTTGGCAGCGGGGCCTGTTGAGGCGCGGCGGAAAGGCCGGAACAGGGCTTCTATCTGCTCCTGATCCATCCCAATTCCTTGATCGCAGATGGCAATTTCTACCTGATCTTCCTTTTTCTTCACTGTGCAGGAAACGGTACTTCCATCAGGGCTATATTTTACGGCGTTATCTATCAAATTGATAAATACCCGCTCTAATAAAGCTGGATCACCTTCGACGAATAAAGGTTCTTCCCAATCATTAAGCGTTATTTTGATCTGGCGTTTATTGGCCTGTATCCATAACTCATCGACTGCGCTGGTCATCACGCCTTCAATTTCAACATCCATCCATTGATATTCGGGCGCTTCTGCCTGTGCTAAACGGGTGAAATTGTCTGCCAATCCTAATGTCCGGCGGGCGTAATTGGAAATCTTGGTAATGATTTCTTGCGCTTCTTTTTCCTTGCTACAGGATGTCCGAGAAAAACGGTCAATCAAGGCCAGAATAGAGATTTGTGGCGACCGCATATCATGGCTTAAAAGATGCAAAATACGCTGACGCTGTTCTTCGGCAGATTTAACGGCACTGATATCAATCAACATAATAAGCCATCCATCAGGCTGGTTAATCACCCGACGGCAAGCCGCGATACGCAGATCAAAAGCTCGGCCATTTTCGGCATAACATTGGCTATTAATCTCATTATTACGGACTTGATCAAAGTTGATCCGATGGCCTTCTTCATTATGGAGATGGTTTAAGATCGTCGAAATCGGCATTCTATAATGATATTGAGCGCCTAATTCTGCGGTTAAATTCTCAGCCGCTTTATTTAATAAAATGATGTTATTATCTTTATCAGTAACAAAAAATACGTCAGGCAAATAATATAAACTATCGGCAATAAAACGACGCATAAAAACAGTGCGAGAAATAGCTAATTTTAAAAGCTGCTTTTTATATTCCAATGGGTCGGCTGCGGTGATATCGGGCAATTTTTGTCTTTGTTCTTCTGGAAAATCGCTTAATAATTTTTCTAATTCATCAGAAAAATATTTACTAAGGCTGGCTAAACGGCTCCAAGCCCAAAAAGGATAGGTAAACGCTACCCCGACAACGGATGTGATCGGCGGGAACCAATAATTAAAAAACAAGAATAAAACCGCACATAAAAGCGGCACCCCTACCCCAAGGGTAACGGTCAATAATATTGTTGCCCTTGGCGATAAAAAACGAAACCCAATAAGCAAGATCCATAGAGATACCAGTGCGACAATCAGCTTGGTAATGTCACTAGCTTCATGGATTGTCCGATCATGAAGCAAGGTATCCAAAATATTGGCTTGAATTTCGACACCAGACATCACTCCGAAAGGCGTCGGATGTAAATATTCAAAACCCGATGCGGTTACACCGACCAGAATTCTTTTACCGGTTAAAAATTCTGGAGGCACCTCGTTGCGCCAAATGGCAGCCGCAGAAATAACAGGGAAACGATTTCGGGGGCCATCAAAAGAAAATAGCTTTTCACGTAAATCAGCTTCGGAATAAACCTTTTTAGGGTTATCCATCAACTCGACCAAAGCAGGCCAGTAGCGCCCCTTTGCCGTCAAAGCAGGCCAATAGCGGCGAACCATTCCATCCCGATCAAAAGGCACACTGACATGACCCACATTGGTTGCAGAGGGTGCCAGAAAAGGTAGAACAGCAACCGTTTTCTTGTTGTGATTACCGGATTCAACCAACATCGGTAAAAATATTGGTGTTTTACTGGTTTTTAAGGTCTTCGATAAATTTTCTGTTGCTTGGGATTCTGAAGGATCAAGAAACAGGACATTATATCCTATTTCCAAAGGATGTCCGGCATCCAATTGTTTGATAAATTTAGCATGTTTATCAGGAGACCATGGCCAAGGTGCTATGGTTTTCAAAGCATTGTCATCAATTTTGACAATAAGAACCGAAGGGTCAGGTTTGTGACATCCCAACCTTACAACGGTATCGTAGAAAAAGAGATCCAACTGCGAAGTCATCCCAGCCCAGCTGATAACCACCACGGCCAAAGTAGCCGCAAGAGCCAATAGAGACCATTCAAAAACGAGTGTATTTTTTAATTCAGTTTCTATTCGTGCAGTGTTCTCTGTATTCAGACTGTCAAAAACATCATTCATTTTTTTTCATCGGGTTATTTCCTGAAATATGCAACTTACGAAAAGGCAATATAATTTGCCCCCCTGCTGGCCATGCTGCAATAATACGCCAGGAATAATCCCCTTCCGGCAAAGAGGAAATTTTTACAAGCCCTGTCTTACCCCCTAATTGATCCACAATAGGGATAGCAGTTTCGCTGATTTTACTAGCGACAACCTGCAAACGACTAATAACTACTTCATTATCTGGTATTTTCCATTGGAAAACTGCCCCCTCAGAGAAAGAATAAGCCGAAGCCTCGAGATGGCCGGTTTTATGATCAATAGGAAAAACTTTTTCCTCGCCCTCAAGATCATGATTATCAACAGCGGAAAGCCGCAAATAATAATGCCCGTCGCCTAATCCTTGTAATTTAACGTCTGTATTATCGAGCCAGCTTTCAGAAAGCAAATCAGAGAAATCTGGATCTTTGGACAATTCAGCATGATAAACAGAGGCCGTCGGCATTTTGCTTAAGAAAATATCGGGCTCGGCATCACGAAGAATGGTTAAACGGTTTGAAGGATTGGGCGGCGTATTCAAAGGAAAATCAAGCTTTTCTATTGAATTGGTACCATATCCGCCAGGAACCGCATAAACTATTTTATGATTATCAGTTGTGACCAAACCTTCTAATACTTCGACAATATTCTCTTTTTTATGGGTCTTGCTATTTTCGATATAATGAACACGAAAATCAGTCCCCTCTGACAGCTGTCAGCGAGGATGGTGTTGCGATATGGAAATAGCTGTCAGAACGGAATAAAGGGGCTGCATGGACGCGGACATGTCCTGCTTCTAATTTGAATGATCGCTCAACCGCTCCGGTCAAAGCTACTTTGCGCAGACGTGTGATGGTAATCTGGCTCATAGAAGGCATGCTGACATGCGAGCCATCCGGCAAAAGAAGGGTTACAAAGCCTGACGAACCCGTCTCAATAGTCATTTGCTCGGTAACGGGCTGGCCTTGTTGCAGGCAACCTCTTTTCCCATGAATAAAAAGAGTAACGGGACCCGAAATATGGGAAACTACAGCGGTAGAAATTTCACGCCGTAAAAACGCTTTAGGGATATTAAGATGGAAGCCTGTATGCAAAGGCTGACTTAAGGAAACGCCAGCCCGCTTCGCAATAGCTTCCATATCGCTTATTCTGTCAAAATAGCGCTGAGCAATAGAAGAAAGCGTATCGCCTTGCTCAACGATATATTCAACGGATTGATGATTTTCGAAATGCGCGGCTACAGCCTTTTCGCTATGGCCGCTTCCTAAAAAAAGAAGTGCACAGCCCAGAAGAAAAGGCCGGAGGCTTCCGCGCTTCCAAAACATTCTTTACCGAACAGCTTCTGCAGCGATGGCTTTCTTTTCAGCTAGCCGTTCCAAACGGTAACCATAGGCATAAACAGGCGCTAACCGATAACCATTTTCCGGTCTCAAATTAAGTTTTGTTCTGATTTTTGAGATATGGGTATCAAGTGTTCGGGTCGGCAAATCTGGATTCCGTCCCCAAAGGGTTTCAAAAATATATCCCCGTGACAATGGTCGATGCAGATTACGGAATAACAGCAAGGAAAGCGTAAACTCCTTTGATGTCATCGGAATAAGCGTATTGCCTAGAGACACCTGCTCTCTTGAAACATCAAAGGTATAATCGTCGTAATGTTCAATACCATCTGACGGTGGTGTTGGATAACTACGACGCAAGACAGCCTTTACCCTAGCCAGCAAGATTTCAGGCTGAACCGGCTTAACCAGATAATCATCTGCTCCGGCATTCAGGCCAGTAACAATATCTTCTGCCGCCGTTCTCGCCGTTGAGAGCAGAATAGGCGGTTTCGGATCGCAATGTTTATTGACCCATTCTATGATTTCAATCCCTGAAAAATCAGGCACATTCCAATCAAGTAATAATAAATCAACCGTTTCGCTGCGCAGCATTCTTAAAAGGGCATAGCCTTTATGGAAAGAACGACAGTCGTAACCCGCTTCAGTCAAAATTGCATTTAACTGAGCAGCCGTTTCCAGATCATCATCTAGCAGGGCTATTCTCACGCCCGTTATTCCTCATCAAAATTACAGATATATACAATGCATATTTCTATGAGATATGCCACTTTCAAGGGGGAATATCCAAATACAACTTAATCATTATGAAGATAATTTCTCATTTTGGGAAATTATACCAAAATAATCTTTTTTTCTGTTCTCAATTATTTGTGCAAAAGCAGGGCTGGTGATTTTTCAGGAAGCCTATAAATTACCGGATATGGTTCGAAACAAAATTTCTATTTTATGGCAGGATATAAACGCATTTATCCGAAATCATGGGCATATCCGGCCAGTGATAGCCATCCTTTCGCTTGCCTTGACGGGGGGCATGGTTTCTATGATGTTTTTTAGCTCAAAGATAGAAAAGCCGGATCCTGAAATTATCTTTGTCCAAAATATCAATGGCGCGCGTAGCGATACCGAAATTCAGTCTAAAAATCTCGAAGATCAAAAAAAACTTGAGGCCAGACAAGAAGAATCTCGCAAGCGCTGGCGTGAATTTGGCCATGTGTTAGGCTATTCAACACAAAATTAGGGCAACATATTTGAAAAGCAGGCTGTCAATTTGACCCATCTTGAAAATGATATCCGCTGGATGCAAGCCGCCATCGCCCTTGGCGAAAGAAGTAAAGGCCTGACTGCCCCCTCGCCTTCTGTTGGCTGTATTATTGTTAATAAAGATAATCAGATCATCGGACGTGGCTGGACACAGTCAGGCGGACGACCTCATGCGGAGGCGATGGCTTTATCACAATGCCAAGCGCTGAAGGGGGCGACTGTTTATGTCACCTTGGAGCCTTGCGCTCATAAAAGTAACAGGGGCCCAACCTGTAGCGATAGTTTGGTTGCCGCTCAGCCTGAAAGAGTAGTTATTGCTTGTCGTGACCCCGACCCCCGAACTAACGGCCAAGGTATTTCCAAAATGGTCGCAGCCGGTATCAAAGTGGAGTGTGGTCTTCTTGAGAAGCAGGCGGCGCAATCGATGTCTGGTTTTTTCAGTCGTCAACTAAAAGCTCGGCCTTATGTTACGTTAAAGATGGCGACTTCGCTTGATGGTTGTATCGCTTTAGAAAATGGCGAAAGCCAGTGGATTACCGGAGAAAGGGCGAGAGCGCATGCCCATTTGGAAAGGATGCGATCAGAGCTGATTGTTGTCGGTCGAAAAACACTAGAATTTGATAAGCCCTCTCTCAACGTCCGATTACAAGGTTTAGGCGATCGTTCGCCGAAAAAAGCAGTTTTAGGCCATGGAGACATCCCTTCCGGCTGGATTGGATTAAGAGAGCCCACAGATATTATCAAAACAACTGCCGATCATGTCCTGATTGAAGGCGGGGCAAAGACAGCCGCCGCTTTTTTAAAGGCCGATCTGGTTGATCGGATATTACTCTATCGCGCCCCTATTCTTATTGGGAAGGGCTTGCATGCCTTGGCTGATATTGGATTAACGCATTTATCTGAAGCGCATCATCGTTGGCATCTCAAAGAGAGAAGAACGCTTGGCAATGACCAGTTGGAAGCCTATTTACGAATATAAAAATGGGCTTATTTACAACAAAATAAATTTATCAAAAAACAATATATAAAATAATTTTATTATCCTTCACAGGAACGGAGCTTACCTCATGTTCACCGGCATTGTTACCGATATTGGCGAGATTACTTCTGTTACGCAGGAAGGCGATCGTCGCATTCGTATTGCGACAGAATATCCTATGGATACCGTTCCTACCGGTTCCTCTATCGCCTGTTCCGGTGTTTGTCTGACCGTGGTTGATAAAGGGACAACGCCCCGCAACTGGTTTGAGGTTACCGTTTCTGGCGAATCTGTTTCCCGCACGGCACCGGGGCGCTGGGAAAAAGGCCAAAAACTTAATCTGGAACGTGCCTTAAAAATAGGCGATGAATTGGGCGGCCATATCGTCACAGGTCATGTCGATGGCATCGGTAAAGTTGTTTCGATTACGGCGGTCGGTGACTCCCATAATTTTCTGATTGAAGCTGGCCTCGAAGTTGCCCCGCATATTGCAGAAAAAGGATCAGTCTCTCTCGACGGCGTATCACTTACGGTGAACGAAGTTAAAGATGTCGATGGCAAAGTGCTGTTTTCTATCAACATCATTCCTCACACCGCCGAAAAAACCACGCTGGGCGATCTGAAAGCCGGTGATTTTGTCAATATCGAAATTGATGTTCTCTCGCGCTATCTTGCCAGAATGAATGCTTTAGGAAATGTCGCGGTATGAGTAAGAACACCCCTATTGTAAAAGGATCGACCAAACGGCATCCTTTTCTATCTTCGGTTGAAGAGCTGATCGAAGAAGCGCGGAATGGCCGAATATTTATTCTGGTTGATGATGAAGATCGTGAAAATGAAGGCGATCTGATTATTCCGGCACAGATGGCAACACCGGCGGCCATCAATTTTATGGCGACGCATGGACGAGGATTGGTCTGCCTCGCCATGACCAAAGAGCGCGTAACTAGTTTGGGTCTAGCCCCGATGTCACGCGAGAATAACGCGCCTCTGCAAACGGCTTTCACCGTTTCGATTGAAGCCAAAGAAGGCGTTACAACAGGCATTTCTGCTGGCGACAGGGCAAGAACCATTGCAGTTGCTATCGACAGTTCTCGGGGTGCAGAAGACATCGTAACCCCGGGTCATGTTTTTCCCTTAGCGGCGAAACCCGGTGGTGTTTTGGTCAGAGCAGGCCATACGGAAGCGGCCGTTGATATTGCGCGCTTAGCCGGATTAAATGCTTCCGGTGTTATCTGTGAAGTGATGAAAGAAGACGGGACAATGGCTCGTCTTGATGATCTGGTCACTTTTGCTCAAAGACATAATATCAAGATAGGCACCATCCGCGATTTGATCGCATGGCGGCGCGAACATGATAATAATGTCGAGTTGATAGAAGAAAAATCTTTCAACAGCCTTTATGGCGGTGATTGGCAAGCCATCCGTTTCAGAAACAAAGCGACCGGCAGCGAATCCTTGGCCTTGGTCAAAGGAGAGATTTCAGCTGATGAACCGGCCCTTGTTCGGATGCACGCCATTGATCCTTTTACGGATATGCTGGGTCAAACAGGCTCTAGGCAGCAGCTTTTATCCCGTTCGATGGAAATCATTGCAAAGAAAGGGGCTGGTGTCGTTGTTCTCGTTCAACGTTCACAGGAAAATAGTGCCGATAAAAGCTCTGTATGGGCTGCCAGCCGAAATCAGGAAACGATTCACCGCGATTATGGTATAGGCGCACAAATTCTGGCGGAATTGGGGGTCAGAGATATGATTCTTCTGACGAACAGCCACCATATGCCTGTAGCCTTGGCCGGATATGGCCTTAACATAACGGGCGAACAGCCTATTACCGAAGGAGCCTGAAATGGCTAAATTCTTAATTGTCGAAGCACGTTTCTATAGCCATTTGAATGATATGCTGATTCAAGGTGCCAAACAGGCCATTGAAGAAGCTGGTCACGAATGTGAAGTCATTACGGTGCCGGGCGCGCTCGAAATTCCGGCAGCCATTACTATGGCATCTGATACCGGTCTTTATGATGCCTTTGTCGCTTTGGGCGTGGTTATTCGGGGCGAAACCTATCATTTCGAGATCGTAGCGTCAGAAAGCGCCCGTGGCGTTATGGCTTTGACTTTAGATGGTTTAGTGATCGGTAACGGAATTTTGACCGTCGAAAATGAACAGCAGGCCTTGGTTCGTGCTGATCCTCAACAAAAAAACAAGGGTGGTGATGCGGCCAAGGCGGCTATTACCATGTTCAATCTCAAGAAAAAATTATCTTAA

Protein sequences of DBSCAN-SWA_2

>NC_018145|897285:905446|903268_903889_+|WP_014848758.1|DBSCAN-SWA
MFTGIVTDIGEITSVTQEGDRRIRIATEYPMDTVPTGSSIACSGVCLTVVDKGTTPRNWFEVTVSGESVSRTAPGRWEKGQKLNLERALKIGDELGGHIVTGHVDGIGKVVSITAVGDSHNFLIEAGLEVAPHIAEKGSVSLDGVSLTVNEVKDVDGKVLFSINIIPHTAEKTTLGDLKAGDFVNIEIDVLSRYLARMNALGNVAV
>NC_018145|897285:905446|900926_901646_-|WP_011240383.1|DBSCAN-SWA
MRIALLDDDLETAAQLNAILTEAGYDCRSFHKGYALLRMLRSETVDLLLLDWNVPDFSGIEIIEWVNKHCDPKPPILLSTARTAAEDIVTGLNAGADDYLVKPVQPEILLARVKAVLRRSYPTPPSDGIEHYDDYTFDVSREQVSLGNTLIPMTSKEFTLSLLLFRNLHRPLSRGYIFETLWGRNPDLPTRTLDTHISKIRTKLNLRPENGYRLAPVYAYGYRLERLAEKKAIAAEAVR
>NC_018145|897285:905446|897285_899577_-|WP_014848755.1|DBSCAN-SWA
MNDVFDSLNTENTARIETELKNTLVFEWSLLALAATLAVVVISWAGMTSQLDLFFYDTVVRLGCHKPDPSVLIVKIDDNALKTIAPWPWSPDKHAKFIKQLDAGHPLEIGYNVLFLDPSESQATENLSKTLKTSKTPIFLPMLVESGNHNKKTVAVLPFLAPSATNVGHVSVPFDRDGMVRRYWPALTAKGRYWPALVELMDNPKKVYSEADLREKLFSFDGPRNRFPVISAAAIWRNEVPPEFLTGKRILVGVTASGFEYLHPTPFGVMSGVEIQANILDTLLHDRTIHEASDITKLIVALVSLWILLIGFRFLSPRATILLTVTLGVGVPLLCAVLFLFFNYWFPPITSVVGVAFTYPFWAWSRLASLSKYFSDELEKLLSDFPEEQRQKLPDITAADPLEYKKQLLKLAISRTVFMRRFIADSLYYLPDVFFVTDKDNNIILLNKAAENLTAELGAQYHYRMPISTILNHLHNEEGHRINFDQVRNNEINSQCYAENGRAFDLRIAACRRVINQPDGWLIMLIDISAVKSAEEQRQRILHLLSHDMRSPQISILALIDRFSRTSCSKEKEAQEIITKISNYARRTLGLADNFTRLAQAEAPEYQWMDVEIEGVMTSAVDELWIQANKRQIKITLNDWEEPLFVEGDPALLERVFINLIDNAVKYSPDGSTVSCTVKKKEDQVEIAICDQGIGMDQEQIEALFRPFRRASTGPAAKISGIGLGLVFVNKVILRHHGHIDCRSTPGKGTCFIVTLPLMVDPE
>NC_018145|897285:905446|905026_905446_+|WP_011240378.1|DBSCAN-SWA
MAKFLIVEARFYSHLNDMLIQGAKQAIEEAGHECEVITVPGALEIPAAITMASDTGLYDAFVALGVVIRGETYHFEIVASESARGVMALTLDGLVIGNGILTVENEQQALVRADPQQKNKGGDAAKAAITMFNLKKKLS
>NC_018145|897285:905446|901827_902178_+|WP_014848756.1|DBSCAN-SWA
MIFQEAYKLPDMVRNKISILWQDINAFIRNHGHIRPVIAILSLALTGGMVSMMFFSSKIEKPDPEIIFVQNINGARSDTEIQSKNLEDQKKLEARQEESRKRWREFGHVLGYSTQN
>NC_018145|897285:905446|903885_905025_+|WP_014848759.1|DBSCAN-SWA
MSKNTPIVKGSTKRHPFLSSVEELIEEARNGRIFILVDDEDRENEGDLIIPAQMATPAAINFMATHGRGLVCLAMTKERVTSLGLAPMSRENNAPLQTAFTVSIEAKEGVTTGISAGDRARTIAVAIDSSRGAEDIVTPGHVFPLAAKPGGVLVRAGHTEAAVDIARLAGLNASGVICEVMKEDGTMARLDDLVTFAQRHNIKIGTIRDLIAWRREHDNNVELIEEKSFNSLYGGDWQAIRFRNKATGSESLALVKGEISADEPALVRMHAIDPFTDMLGQTGSRQQLLSRSMEIIAKKGAGVVVLVQRSQENSADKSSVWAASRNQETIHRDYGIGAQILAELGVRDMILLTNSHHMPVALAGYGLNITGEQPITEGA
>NC_018145|897285:905446|902208_903180_+|WP_014848757.1|DBSCAN-SWA
MTHLENDIRWMQAAIALGERSKGLTAPSPSVGCIIVNKDNQIIGRGWTQSGGRPHAEAMALSQCQALKGATVYVTLEPCAHKSNRGPTCSDSLVAAQPERVVIACRDPDPRTNGQGISKMVAAGIKVECGLLEKQAAQSMSGFFSRQLKARPYVTLKMATSLDGCIALENGESQWITGERARAHAHLERMRSELIVVGRKTLEFDKPSLNVRLQGLGDRSPKKAVLGHGDIPSGWIGLREPTDIIKTTADHVLIEGGAKTAAAFLKADLVDRILLYRAPILIGKGLHALADIGLTHLSEAHHRWHLKERRTLGNDQLEAYLRI

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014848755.1|897285_899577_-	CHASE2 domain-containing protein	A0A2K9L0Z8	Tupanvirus	4.4e-09	27.5
WP_011240383.1|900926_901646_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.7e-21	30.4
WP_014848756.1|901827_902178_+	hypothetical protein	NA	NA	NA	NA
WP_014848757.1|902208_903180_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	2.1e-37	31.7
WP_014848758.1|903268_903889_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.7e-22	35.7
WP_014848759.1|903885_905025_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.2e-47	36.1
WP_011240378.1|905026_905446_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2I2L4Y7	Orpheovirus	9.8e-08	33.9

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NC_018145|977834:988318|DBSCAN-SWA
CTCACATAATAAAGTGATTAACGCGCAAATAGCGATAATCAGGATGATTGAGTAAACGGCGAACGGCAGGCGCGTGATTTTTGTCCCAATATCGGACACCATATTTCACCAGCCATTCCATCAGAACAACGGCTGGAACATGGGCGGCGTGCCACATCGAAGAACGCCGATCAAAATCTTCATTTTGTGCCTGTTTATTGGCTTCCAAAGCCGCAGAGCAATCCTGTTCATAGCGGATATGCCAACTGCCCTGATTCTCCTCCGAAGAGGAAAACCAACTTTTAAGCCCCGTCACCGGATTATAGGATAACAAGCGTTCAGCAGCCATCATGCCCTCGAATATCAAAGCCGCATTTCAAGCCCAGCCCGACCTTTTTTTTGAAAAAGGCGACCAAGGCAAAAGAAAAAGCCATGGAATATTCCCTTTCCGAATTTTTACGGGAAGATGCCTTGCAAGAAGACATCCTCCCGATCACGAAAATCAGGCAGCGCTTAAATCTGCCAAAACACCGGAGGCTGCTTCATTATGGCAGCGCAAGGCAATTTCAGTGTAAAGGGCATCGCGATCAGCCAGCCCCGTTGTTGCCAAAGACCGTTTCTGAATCGGATCTAAGGTCGCAACCGACCAATATTCAGGGTCAATGACCAAAGCGCTGCTATTGTCGCAAAAACGATCAGGTACAAACTGGACTTCGCCGACATCGGAAACATAGATATCCGCACCGGCAATAATACGCGCTTTCTGGTCGCCCGTATCGCGCCGGTTAGAAGCCAACCCCGGAAAGGCTGCCGCCGTCTGTTTCAGCTTCAAAGAGGTAATCACCATATTCGGCTGACCACCACTGACCCAAATGTCGCCCAAAACGTCTTTTAACAAAGACTCGGTATAAAGCCGTGCCTTACCCGCGGTCGCCGCTGTTGTCGGATAACCGCTGCCATTGTCGCCACCGGACATTACCGGATTGGCACCGCCGTCACCACGATGGGCATTACTGCGCAGCCATGCCAAAGCCCCTGCGGTTTCGCGCGCGACAACCGCCCCATCTCCGGGAATGGCTGCAAAATTACCGGTAAAGCGCGCCTCAATATCGCGTTTCAATTCCTGACCAGCACGTGCCAACTGATAGGCATGTTCATCCCCGCGTCCGGCATTATGCACTGCCCGATCGGTCGTCGATGTCCCGACAACTTTGGTCATGATCTGGGTATAATTGCCGACCCGAACCGTTGGCTGACGGCTTTCATTGGCAAGATCAGCCCCTTCGACCTGTTTATTCTGGGCATTGGCGCTGGCGAGATTGTCGGTCTGCCATTCGGTATAGGTATTTTTGGCTGTCGTTTGACCGATAGCCGTTACAAAAGGTGTTTCCAGATTGTTACCGCAAAGGCTCTTTATCCCTTGCTTCCTTACATTCCTGCAAGGCTCAGACTATATCATCGCTTTCGCGGGCGGCACTCGTGTCAGCATTACTGCCATGGACAAAAAAGACTGAAATATTTCTTCCGAAATTTCCGGCATTTTCAGTAAAAATGAAAAGAATCATACCCGCTTCTTTTTCAAAAATAACGGCATCAGTTTTATCGTTTTTTGTCGGTAGGCTCGGCTGTTAGTCGTTACACCTTCAAGAGATTTTCACCTCAAGCTTGGCTCGGGATTATCCTCGTCTATGACGGTTGGACGTCCCCCGAATTCACCGCCTTTTCATTTAATGCAGCGTATAAACTACATTAACGGACCAAGACTCCAGTCGGGCTGATATTGTAAATAATATCGGAAAGATCTTCACGAATACCGACGCGCGAATAGGTTTGGACGGTATTAGAGGCAACAGACATAATTCAAAATTCCTTAAAAAGTCGATTATTTAAAAAGGGCATTCATCGCTGCTGCGGCTGACCGGACATCGCCGGTTTCGCGAAGCTGCCCCAATGATTCATTCAGTTTCCGGCTTTTGGCCGCACCATAAGGCTGGGACGTTCCCGGAACCGCGGTTTTTCTCGATGTTTTAGCCGATTGGATAGCCGCCGTCTTACCCTGTTGTAGGGCATCCCATTTTTCGGATTTTCTTCGCCATTCATGGGCTTTTTTCAAAGCCATAATGTCGTTGGAATCAGCCGCGGCTAGAACATGATCTGGATAACCGAGATGCCGCCCCGTCTCTTCAAAAGCTGCTAAGATAGCCGGTCTCTGATTATCATCGCTCCATTCGGGCAAAAGCGATATCAAACGCTGATGTTCGCCCTGCGCCCATGCTCTTCTGGCAGCCAGTTCAGTCATTTCATTCTGGCGAGAAATCTGGATAACTTCCTGAACGATTTGGTCACGTTTGGCCGTTAAGTCTTCATAACTTGCTAATTGTGCGGCATAGCTTGCCGGATCACTGACCAATAACTGCGGATCAGGTTTTTTCGGGGTAATCGCTTCGGCATATTTAGCAAGCTGGTCGGCATAATGGAGGTGCAAAGCTCGACAATGCTCCTGCCAAGCCGCACTCATATCCGGCTGATCCTTTCCTTGATTGGCACCATTTCCTGCTGCCGTTGCCCCCATATTGCTCTGATCGTCGGATGCCTGATCGGATGGCGGCATATCCGTATTATTTCCAGCCATCGGGTTATCCTGATCCGGTGCCAAATTGGCTTGCAATGCTTCGGCAGCGTCCTGAATAGACCGACGAGGTCGCTCAAGGCTGCGCCTTTTATATTTGTCATTATCAATATTCCTGAATGTCCAACCGGTAAAATGGGCGCAGAAGATCACTCCGGTGACTCTCTTTTCAGCCACCCAGCCGGTTTTATCTCGATAAATAGAATGAAGACCTTGGTAGCTCGGCCTACAGCCAGCGACGTTTTCGCTCGGGTAAATTCTCTATTTTTCGGGCATGTTCTTTGGCCTGATCAGCCAATTGCCCATCTGCAATAATCACTTGAATCAAGTTATCAATTTGCCCCACAATTCGATTAGCCATCGCCAAACGTAATAATTTTCGGTCAGCTTCGGCTTCCCATGGGGCAATCTCGGACATACGCTGGATATAACGAGTGCCGATTTCTTGCAAAATAGCTTTCAACCCGCCCTTTTCTTCATAAAAGGCTTTCCAACGCCTTGCCCGCAAAATGGGATCTTGCTCCATTATTTATCCAATGCGCCCCCTGCTTTGTTTTGCGGCACCCTATCCCTCTTTTTATCTGCTGGAATATTTTTTCCAGCTTCTGCCAATTTCAAAGCGATCTGATAATTACGATCGGCTGTTTCCTTGGCAAGCGAGGCTTCAAAATCAGAACGTTGCCTTGCTAAAATGGCCTCTTCTTCGGCTTTTTCACGCACCAAGGCCAAACGCTGTTTATGCTCTTCCTGTTGCATCGCCAGCTTGGCTTCGGTTTCCTGCTTTTTTAAAGCAAATTCGGCCATACTCCGTTCCTGATCAGCAGCCATTTTCTGCCCTTGAAGATTGATATCTTGTCGGGCTTTCAACTCTGTATAATCAGGATTATTTCCTACACTGCCAGAAGAATTTTGCGGGGCATCCGAATTATTATTCACAGGATTTTCAGCCTGATTACCTGCCAAGCGAATATCAGGATCGATCAAATAATCAGTCGGATTACCCAAACCACAATCTCGGATCATCGCGGCGATATTGTTATAAATCTGCTTAGAACCGGTTAAACCAACGGCCAAAGCCTGTTGCTGAATAGATAACAACTGCTGACGATAGGCCAAACGCTGATCTTTTCGTCCCGATCCCAAGCCGACCGTGACACGCACCCGCATATCCGGCGGCCACAAAGCCGGATCAACCGTTTTATACAGACCTTCAACCTTGATTGCCATCGGATCGCCTGATGCAATCATCAACCATAATTTCTTTTGGAATAACCGCCCAAGACTTTGTGCAAAATTGCGGGCAACATATTCTTCCATTTGCTGCCCTTGCGCCTGAAGCAAGGCCTGACCGGTCGCGGTTTTATTAAGACTGTCAGCATCCAATCCCTGATTAAGACGGGTAATCCCCGTCCGGCTTTCCTGAGCCGACTGCATATATTCGATCATACCCAAAGATTTTTGGATATCGAAACCGGCATTTAACGGCGTTGGTGGAATGCCACCCCGATAACGGACGATTGCCCCAGGTCTGATTGTCAATAAATCGTCAAAAGTATCTTCGGTTAAACCATCGACATTCACCGCCATGCGTGGCGCGTTGGTCTGGTAAACCCCGTCCAAAGCCTGACGCATCAACACCGATTTGACCCGCTGGATATCCATTACCTTTTCAGCCAAAGAATTGCCAATCATCCGATGGGCGCGTGGGAAAGGTGTCCAGACGACAAAGGGGGCTTCGTCTACTTCTTCAATCGAAAGTAAGACATCTTTTACTCGAAAAATCTGCAATAATTCAGCAATGCCATCGCCATCCCGATCGATGCGGACATATTCTTCATATAAGAGAACTTCGCGATTGGCTTGATCGCTGCTGCCGGACAAAAAAGATTCATCCCGCCATCTGGCATCCGAACGACCATCACTATTTGGAAAATTCTTATCAGTTGGCAGGCTATCGACAATATCGCGATCGAATCCCATCGACAGAAGATCAGACAGCGTTTTATAACTGACATGCGCCTGATAATCAGCATCATCTTCATGGCGGGTTCTGGCCGAAACGCGATATTCTTCTGACGGGATTGGCATATCGACATAGCGTTTTTGGAGCTGATAACGGGTAACGGTTACCTCATATTGACCGCTACCATCGTCACTATCCAAGGTAATCTGAATATCGGGATTATCTTCGGCCTCCATCAACAAAACCGCCAAGGCATCATCATTCACAGTAATATGACGGATCGTGGCACGTCTTTCCGATAGAACAGCGGTTTTAATGATGCCTATTTTTTCAATCAGTCCCGACTGTATCCAGTCATGCAGGATTTTATAGCCGTCCTGCCCATGCATAAAAGCGTAGCTGACAGCCTCGGTCGCATCATCGGCATCTTGCGCTTGGTCGGCAGCCACCGGCTCAAATTCAATCACCCGATCACCGGACACAATTGTCCGTAACAGACTAATCGTCATATAATCGACTACCTCGGCAACATCGGGACTAACGACCTGACTCCGTCCATCCTCTTCATCACCAAAGGGGCGCGCTTCATAAAAATCGATAGCATTGGCCTGATCTTCAGCCAGTAAACTATTATGCCAGCTTTCTGCCTGATCGGCTTTCTCTCGCAAGACCGCCAATAACTCACGGTTAGAAAGCAAGGGCTCCCCCTGTTTTTTCTTTAAATCTGTCTGTCCATCAATATCCAAAGACATACTACCCCCTTCGGGGCAGAAAGTTATTTTCAGCCCGTTTCATTAAAATATTCCTTTATTGCTATAGGTGATTTTCCGACTGGTTACCGGCGGTTCCCAGGCAATAGCCGCCAAACCGAAAGCATCCGCGGAATGACTTGACCAATCATGATCGGGTCCCAATCCGATCCCTCGTATTTCATCTCGTTTTTCGTGATACCATCCAAGGGCTTCCAAACCGCCACGGCAGTGATTTTCATCAAACCACATCTGGGGAAATAACCGACGAGCTGCTTCAATCCGTTGCATTGCCGCTCCAGCCCCCTGATTAGGGATAATTCGCACCGAAAAACCGGCTTCACGCAACGCGCCTTCATAGGTCGTCGAGGCGATTTTATCATGCTGTGCGCCATCATGAGGCAGAATACATAAAACGCCGCCATAATCATTTGACCTCAACCAATGAAGATGGGCAGATAAGGGCTGCCCTTGCGCCTCATAATGATTGAGGAAACGGATTTCCCGTCCGACATATTGGACAATCCATATCGCGGTAGCATCGGCTTTGGCACCCGTGCCGCCGATATCCCAAACCGCCCGCAAGGTCATTAACGGGTCAGCGGCAACGACAGCTATCCGTTTTTCAGATCGGGCTTTTGCCAAGGCTTGGGCATAATAAGCCCCCTCGGTTATCTCCGCATATCCCCCTTCCCATATATGGCGGTATTTATCAGGATCATTCGCCAGGCAATCCCGCCTTTCCTGATCCAACGGCGAGGGAAACCACGGGTTATTTTCCCAATTAGCTTGAACCACAACAGCACCGGTCGGTGGCGTTTCGCCGCGCAACATCCGGTCAACCGGATCAGTTTTGAAACGAGGATTCCACGAAAACCATAATTCTGAATCAATCGTTCTGATAGTTGGCCTTAAAAGCTCTAAAGATCGTTGGGACAGAGTCTGCGCTTCTTCGACCCATGCTCGTGAAAAGCCTTCCAAAGACTTGATGCTTTCGGCGGTATGGTCTTGCATCCCTTGAAAGATGATAACACCATTGCCGGGGGTTTGGATGTGGTCACGAAAAACCCGAAAACCGACATTGCTTCCCAAATGATAGGCCGATAATTTCGCCTCAATCAGCCTTTTCGCTGAATCTTTCAGGGATTTTTGAACTTCTCGAATACAGACAGCCCGCAATCCCGGAAGGCGAAGACAATCTTCAACCAACATTTCCGCGAAAAAATGGGATTTACCGGAACCTCTTCCACCATAAGCCCCTTTATAGCGTGCCGGTTTTAATAAAGGCCTAAAGACTTTGGCGGTTGGGATTCTCAAAGCTGGAAAAGACATCACATCTTTTCCATATCAACAGGATCTTTATCCCATTCCGCAGAGGATATAGGCCGATCAGAGGCGTTATGCTCTTCGCCGACAATGACGCGTTCTATACGCGCCAAAATAGGCGCACCATTTTGGCCAGTTATTTCTGCCGTTTGTTTGTCTCGCCATTGTTTCGGACGGCGATTTCGTAACCAAAAACTACAGGCCGTAATATCTGGCGGAAGATGCTCAACAAATTCTACAACTTCAGGCTTGCCAGAAACCATCACCACTTTTTGGCAATCGTAACTATAGCCGACAGCTCTTTGATAGAGCGAAGCCTCAACCCGATTATCCGCCGCCGCTTTTCCAACCCTGACAGCATTGGCAAAATCGGGATATTTCAAAACCCAACGATTGATCGTGCGTTCGCTCACACCAAAAAAATCGGCAATATCGCGATTAGTTGCTCCTAATTTGGCAAGATTGCGCGCCTGTATGATATATTCAATTTTAAAAGTAGAAGAAGCCGTCATGAAAATTCTATTAAAACAGAATTTACAACAACAAAGAGTGGGCAGAAATAAAGAGATTAGAAAAAATTGAAGTTAAAATAAAATCAGCAGAAATTTTTATTTCGATATTGATGCCATAAAAACAAAGCCATTATACTTCTATAAGGACAGAATATATCCCCAAGACCGCGCGTTTCTTTCATATCGGGTCTATTGGGTAACTGATAAAGATATCCGGTGGCAATCCTTATCCCTAAATCAGCCGCAGGCCAAATATCCAAACGTCCTTCGGCAAAGATCAGATAATTTTCAGCCGTCCAACGACCAATCCCATGCACGGACATCAAAAGATCGACCGCATCATCATCTCCTTCGGGCAAAGCGAACAAATCCAACCCCGAGACAGAGCGCATCGCCAAATCTTTTAAATAAGCAATCTTTGACGGTGACAGTCCACATTGCCGCAAAATCGCCCCGTCAACAGACAAAAGACGATCAGCCGTAATGTCTCCGATAGAACAGACTAGTTTTTGCCATACCCCATCCGCGACTTTGGTATGAAGCTGTTGCCCGACAATCACCCGAGCCAGACTGGAAACGCCTCTTTCGACGGCTTGATAAAGTGGATAACCAAATTGGCGCAGCCCTTGTTGCATCAAGGGATTTTCAGCGGCCCATTGATCCAGCTTCTGTTCAATATTCTGTTGGCACAGAGATTGTTTCATCTTATCCAATCACTATATTTCTATCATCAGTAAAAATTTTTATTGTTACGCATGCACAAAGTTTTATTCTATGTTATTTTAAATTCTTTTCCCAAATAAGTTATTTTCCTGATAGACCCCCCGTGATTGAACCCAGAAAGATCGACACCATATCTATGAAAAGGTGTGAGCATTTTGCCGCCCCAGTGGAGTTGTGATGAAAGAAACCCTTCCCGTTTTACCGCTGCGCGACATCGTCGTATTTCCTCATATGATCGCGCCGCTTTTTGTCGGTCGTGAAAAATCGGTAGCAGCGCTTGAAAGCGTGATGGCAGCAGAGAAAACTATTTTTCTTGTTTCCCAACGCGACCCGGCTGAAGAAGACCCTAATCGTGAAGCGCTTTATGACGTTGGCGTGGTCGCGAATGTGTTACAACTTCTTAAATTACCCGATGGCACCGTGCGGGTGTTGGTAGAAGGCCGGAAACGCGCCAAAATAATCGACATGGATGATGCCAGTGGCCATCTAATCGCCGAAGTAGACCCCCTTGAGGATGCCTCTGTCGAAAATGACGAGGTCGAGGCTCTGATGCGCTCGGTCAAGGATCAGTTCGAACATTACGCTAAACTCAATCGCAAATTACCGGGCGATATCGCCCATGAAATCAAAGAGATTGATGCCCCGTCTCGACTGGCTGATGCGATCGCTGTTAATTTGGCTGTCAAAGTGGCCGACAAACAGCCGCTTCTCGAAGAGCTGAATCCTTCAAAAAGACTGGAAATGACTTTTGGCTTGATGGAAGGCGAGCTTGGTGTTTTGCAGGTTGAACGCAAAATCAGAAGCCGCGTCAAACGCCAGATGGAAAAGAACCAGCGAGAATATTACCTCAATGAACAGCTCAAAGCTATTCAAAGAGAACTTTCCACCGGTGAGACGAGTGGCAATGATGACGAAGATGTTGATGGAGACGAACTCTCCGAATTCACGCAAAAGCTAAAAAATCCCAAACTTCCGAAAGAAGTAAAGGCCAAAGCCAGCTCTGAATTGAAAAAATTGCGGACGATGGGCGCTATGTCTGCCGAAGCAACGGTGGTGCGCTCATATCTTGAAACCTTGCTGAATATGCCTTGGGGCAAGAAAACGCGGGTTAAAAAAGATATTATCGCTGCTGAAAAAATTCTTGGTGAAGAGCATTTTGGCCTTGATAAGGTTAAAGAGCGGATTGTCGAATATATCGCGGTTCAAGCACGCACCAACAAGTTGAAAGGGCCTATCCTTTGCCTCGTTGGGCCTCCGGGTGTTGGGAAGACGTCATTGGCACGTTCTATTGCCAAGGCAACAGGTCGTAACTTTGTCAGACAGTCGCTCGGCGGCGTTCGTGATGAAGCCGAAATACGCGGCCATCGTCGGACTTATATCGGCTCACTTCCGGGTAAAATTGTCACTAACATCCAAAAAGCAGAAAGCTTTAATCCGCTCTTTCTGCTCGATGAGATTGATAAATTAGGACAAGACTCCCGTGGTGATCCAGCGTCAGCTTTGCTTGAGGTTTTAGACCCCGAACAGAATAATAAATTTCAGGATCATTATCTTGAAACCGATATTGATCTTTCGGATGTCATGTTTGTGGCAACGGCCAATTCTTTGAATTTGCCAGCCCCTCTAATCGACCGCATGGAAATCATCCGCCTAGAAGGCTATACTGAAGACGAAAAAATCGAGATCGCGACCAGCCATCTTTTACCGCGTCAAATCAAATCTCATGGTTTGAAAAAAGGTGAATTTACGGTTGAGGTAGACGCTATCCGTGATCTTATCCGCTATTACACCCGTGAATCCGGTGTTCGTGCGCTGGAACGTGAACTGGCTAAAATTGCCCGTAAAGCCTTGCGGCGTATTCTTGAGAAGAAAGCCAAGGCGATCACGGTCACGGCTAAAAATCTGAGCGATTTTTCGGGTGTCCGGCGGTATAAATTCGGTATTTCCGAGAAAGAAGATCAGGTCGGTATCGTCACGGGTCTGGCATGGACAGAGGTTGGTGGCGAATTGCTGACGATCGAAAGCGTCACTGTTCCGGGTAGAGGCAATATCCGCACGACGGGTAAACTTGGCGATGTGATGAAGGAGTCCATTCAAGCGGCGTTGTCCTTCGTCAAATCACGTGCACCCTTCTATGGCATTAAACCTAGTATCTTTACTCGGAAAGATGTCCATATCCATTTGCCGGAAGGTGCTGTTCCAAAAGATGGACCTTCAGCGGGTATCGGTATTGTGACAGCGATTACGTCGGTTTTGACCGGTGTACCAGTGCGCCGCGATGTCGCTATGACCGGTGAAGTCACCTTAAGAGGTCGCGTCCTGCCGATCGGTGGATTGAAAGAGAAACTTCTTGCCGCCCTAAGAGGCGGGATCAAAACGGTGTTAATTCCAGAAGAAAATCAGAAAGACCTGATTGAATTACCGGAAAACATTAAAAAGGGTCTCAAGATTATTCCGGTATCGCATGTTGATGAGGTTCTGGCACTCGCTTTGACTGAAAAGCTTGATCCTATCGACTGGAGCGAAGCCGATGATCTGGCCGCTTTCCCGCCGACGGCTTTGAACCATCATGCGTCAGATAGTGTCAGCCCTGTGCATCATTGA

Protein sequences of DBSCAN-SWA_3

>NC_018145|977834:988318|980667_980967_-|WP_011240301.1|DBSCAN-SWA
MEQDPILRARRWKAFYEEKGGLKAILQEIGTRYIQRMSEIAPWEAEADRKLLRLAMANRIVGQIDNLIQVIIADGQLADQAKEHARKIENLPERKRRWL
>NC_018145|977834:988318|980966_983156_-|WP_014848823.1|DBSCAN-SWA
MSLDIDGQTDLKKKQGEPLLSNRELLAVLREKADQAESWHNSLLAEDQANAIDFYEARPFGDEEDGRSQVVSPDVAEVVDYMTISLLRTIVSGDRVIEFEPVAADQAQDADDATEAVSYAFMHGQDGYKILHDWIQSGLIEKIGIIKTAVLSERRATIRHITVNDDALAVLLMEAEDNPDIQITLDSDDGSGQYEVTVTRYQLQKRYVDMPIPSEEYRVSARTRHEDDADYQAHVSYKTLSDLLSMGFDRDIVDSLPTDKNFPNSDGRSDARWRDESFLSGSSDQANREVLLYEEYVRIDRDGDGIAELLQIFRVKDVLLSIEEVDEAPFVVWTPFPRAHRMIGNSLAEKVMDIQRVKSVLMRQALDGVYQTNAPRMAVNVDGLTEDTFDDLLTIRPGAIVRYRGGIPPTPLNAGFDIQKSLGMIEYMQSAQESRTGITRLNQGLDADSLNKTATGQALLQAQGQQMEEYVARNFAQSLGRLFQKKLWLMIASGDPMAIKVEGLYKTVDPALWPPDMRVRVTVGLGSGRKDQRLAYRQQLLSIQQQALAVGLTGSKQIYNNIAAMIRDCGLGNPTDYLIDPDIRLAGNQAENPVNNNSDAPQNSSGSVGNNPDYTELKARQDINLQGQKMAADQERSMAEFALKKQETEAKLAMQQEEHKQRLALVREKAEEEAILARQRSDFEASLAKETADRNYQIALKLAEAGKNIPADKKRDRVPQNKAGGALDK
>NC_018145|977834:988318|983198_984485_-|WP_014848824.1|terminase|DBSCAN-SWA
MSFPALRIPTAKVFRPLLKPARYKGAYGGRGSGKSHFFAEMLVEDCLRLPGLRAVCIREVQKSLKDSAKRLIEAKLSAYHLGSNVGFRVFRDHIQTPGNGVIIFQGMQDHTAESIKSLEGFSRAWVEEAQTLSQRSLELLRPTIRTIDSELWFSWNPRFKTDPVDRMLRGETPPTGAVVVQANWENNPWFPSPLDQERRDCLANDPDKYRHIWEGGYAEITEGAYYAQALAKARSEKRIAVVAADPLMTLRAVWDIGGTGAKADATAIWIVQYVGREIRFLNHYEAQGQPLSAHLHWLRSNDYGGVLCILPHDGAQHDKIASTTYEGALREAGFSVRIIPNQGAGAAMQRIEAARRLFPQMWFDENHCRGGLEALGWYHEKRDEIRGIGLGPDHDWSSHSADAFGLAAIAWEPPVTSRKITYSNKGIF
>NC_018145|977834:988318|979561_979669_-|WP_011240303.1|DBSCAN-SWA
MSVASNTVQTYSRVGIREDLSDIIYNISPTGVLVR
>NC_018145|977834:988318|977834_978161_-|WP_011240306.1|DBSCAN-SWA
MAAERLLSYNPVTGLKSWFSSSEENQGSWHIRYEQDCSAALEANKQAQNEDFDRRSSMWHAAHVPAVVLMEWLVKYGVRYWDKNHAPAVRRLLNHPDYRYLRVNHFIM
>NC_018145|977834:988318|978314_979229_-|WP_041572913.1|DBSCAN-SWA
MKSLCGNNLETPFVTAIGQTTAKNTYTEWQTDNLASANAQNKQVEGADLANESRQPTVRVGNYTQIMTKVVGTSTTDRAVHNAGRGDEHAYQLARAGQELKRDIEARFTGNFAAIPGDGAVVARETAGALAWLRSNAHRGDGGANPVMSGGDNGSGYPTTAATAGKARLYTESLLKDVLGDIWVSGGQPNMVITSLKLKQTAAAFPGLASNRRDTGDQKARIIAGADIYVSDVGEVQFVPDRFCDNSSALVIDPEYWSVATLDPIQKRSLATTGLADRDALYTEIALRCHNEAASGVLADLSAA
>NC_018145|977834:988318|985074_985695_-|WP_014848826.1|DBSCAN-SWA
MKQSLCQQNIEQKLDQWAAENPLMQQGLRQFGYPLYQAVERGVSSLARVIVGQQLHTKVADGVWQKLVCSIGDITADRLLSVDGAILRQCGLSPSKIAYLKDLAMRSVSGLDLFALPEGDDDAVDLLMSVHGIGRWTAENYLIFAEGRLDIWPAADLGIRIATGYLYQLPNRPDMKETRGLGDIFCPYRSIMALFLWHQYRNKNFC
>NC_018145|977834:988318|984484_984991_-|WP_014848825.1|DBSCAN-SWA
MTASSTFKIEYIIQARNLAKLGATNRDIADFFGVSERTINRWVLKYPDFANAVRVGKAAADNRVEASLYQRAVGYSYDCQKVVMVSGKPEVVEFVEHLPPDITACSFWLRNRRPKQWRDKQTAEITGQNGAPILARIERVIVGEEHNASDRPISSAEWDKDPVDMEKM
>NC_018145|977834:988318|979694_980552_-|WP_141276043.1|DBSCAN-SWA
MDNDKYKRRSLERPRRSIQDAAEALQANLAPDQDNPMAGNNTDMPPSDQASDDQSNMGATAAGNGANQGKDQPDMSAAWQEHCRALHLHYADQLAKYAEAITPKKPDPQLLVSDPASYAAQLASYEDLTAKRDQIVQEVIQISRQNEMTELAARRAWAQGEHQRLISLLPEWSDDNQRPAILAAFEETGRHLGYPDHVLAAADSNDIMALKKAHEWRRKSEKWDALQQGKTAAIQSAKTSRKTAVPGTSQPYGAAKSRKLNESLGQLRETGDVRSAAAAMNALFK
>NC_018145|977834:988318|985891_988318_+|WP_014848827.1|DBSCAN-SWA
MKETLPVLPLRDIVVFPHMIAPLFVGREKSVAALESVMAAEKTIFLVSQRDPAEEDPNREALYDVGVVANVLQLLKLPDGTVRVLVEGRKRAKIIDMDDASGHLIAEVDPLEDASVENDEVEALMRSVKDQFEHYAKLNRKLPGDIAHEIKEIDAPSRLADAIAVNLAVKVADKQPLLEELNPSKRLEMTFGLMEGELGVLQVERKIRSRVKRQMEKNQREYYLNEQLKAIQRELSTGETSGNDDEDVDGDELSEFTQKLKNPKLPKEVKAKASSELKKLRTMGAMSAEATVVRSYLETLLNMPWGKKTRVKKDIIAAEKILGEEHFGLDKVKERIVEYIAVQARTNKLKGPILCLVGPPGVGKTSLARSIAKATGRNFVRQSLGGVRDEAEIRGHRRTYIGSLPGKIVTNIQKAESFNPLFLLDEIDKLGQDSRGDPASALLEVLDPEQNNKFQDHYLETDIDLSDVMFVATANSLNLPAPLIDRMEIIRLEGYTEDEKIEIATSHLLPRQIKSHGLKKGEFTVEVDAIRDLIRYYTRESGVRALERELAKIARKALRRILEKKAKAITVTAKNLSDFSGVRRYKFGISEKEDQVGIVTGLAWTEVGGELLTIESVTVPGRGNIRTTGKLGDVMKESIQAALSFVKSRAPFYGIKPSIFTRKDVHIHLPEGAVPKDGPSAGIGIVTAITSVLTGVPVRRDVAMTGEVTLRGRVLPIGGLKEKLLAALRGGIKTVLIPEENQKDLIELPENIKKGLKIIPVSHVDEVLALALTEKLDPIDWSEADDLAAFPPTALNHHASDSVSPVHH

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011240306.1|977834_978161_-	hypothetical protein	A0A218MLW6	uncultured_virus	5.1e-12	41.9
WP_041572913.1|978314_979229_-	DUF5309 domain-containing protein	A0A1Y0T0F4	Sinorhizobium_phage	4.5e-66	48.8
WP_011240303.1|979561_979669_-	hypothetical protein	NA	NA	NA	NA
WP_141276043.1|979694_980552_-	hypothetical protein	NA	NA	NA	NA
WP_011240301.1|980667_980967_-	hypothetical protein	NA	NA	NA	NA
WP_014848823.1|980966_983156_-	hypothetical protein	A0A1B1IQR4	uncultured_Mediterranean_phage	5.8e-75	32.4
WP_014848824.1|983198_984485_-|terminase	PBSX family phage terminase large subunit	F8TUR5	EBPR_podovirus	2.7e-173	69.2
WP_014848825.1|984484_984991_-	helix-turn-helix domain-containing protein	W6MWW3	Pseudomonas_phage	1.3e-25	47.1
WP_014848826.1|985074_985695_-	DNA-3-methyladenine glycosylase 2 family protein	A0A0B5J929	Pandoravirus	1.1e-10	25.9
WP_014848827.1|985891_988318_+	endopeptidase La	A0A0R6PGP8	Moraxella_phage	3.5e-206	48.3

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NC_018145|1091000:1153371|DBSCAN-SWA
CTCATAGCCAGAACAAGACGGTTGCAGCGAGGCAGATTGCCGAGAAGAAGACGGTCGGGCATCTATCGTAGCGGGTTGCGACCCGCCTCCAGTCTTTGAGCCTGCCGAACATGATTTCGATACGGTTGCGTCTTTTGTATTTCCGTTTGTCGTATTTGACCGGTTTTGAACGAGATTTTCGACCAGGAATACAGGGTTTGATCCCTTTCTCCTCCAGGGCCTCTCTGAACCAGTCAGCGTCATAGCCCCGATCTGCCAGCATCCATTCGGCTGATGGCAGACTGTCCAGAAGGGCAGCGGCACCAGTATAATCACTGATATGACCTGCTGTCATGAAGAAGTCGAGCGGACGTCCGTTCCGGTCAGTGACAGCATGCAGCTTCGTATTCATCCCGCCTTTGGTCCGCCCGATCAAACGGCCTGGGCCCCCCTTTTTTAACCGCAGGCTCGAAGCCGTGCGATGTGCCTTGAGATAGGTCGCATCAATCATGATTGTCTGAGGCTCTGCCTTGCCAGTAGCCAATCCCTCCATCATGCGGATGAAGATCCCCATAGCACTCCAGCGCTTCCAGCGGTTGTAGAGCGTCTTGTGTGGACCGTATTCCCGAGGCGCATCACGCCAGCGCAGACCATTTCTGTTCACGAAAAATGATCCCACTCAACACACGACGGTCATCAACGCGAGGTTTGCCATGGCTCTTCGGGAAAAAGGGCCGCAGACGATCCATCTGTTCCTCGGTCAGCCAATACAGGTCACTCATCTTCACTCTCCTCACAGAGCCTGAATCAGATTTCCGCAATCAAATCAATGGGTCCTGAGCCTAGTAAAGCCGCTGAATCGCGCAAAAGAAGCCTTGAGAGAAAGATAAATACAAGTAGATTATTTTGATCGATAAATGAAAAGATAATTTTCAATTTCAGAAGATCTTGAAACTATGCGTAAGGCTATGGGTTATTAGATTAAATTTTTGAAAATAAAAGGTTAATATAATGGTGCAGCTTCCTTCTTCTGCTCGACATGGGAATGAAACAGAAAATCAGCAATTTCTGGATCATCTTCGTGAAATCTCGGATCATGTGCTGACTTCTGAAGGCGAGATGCATCATTATTGCACTGGTTTCCGTTTTGGTAGTGGCAAGGTTTTAGCGGTTGTTCGTCCAACTTCCTTGGTTGAAATGTGGCATGTCGTTGAAGCCTGTGTTGATGCCGGCAAGATCATCATTATGCAGGCGGCCAATACCGGATTGACCGGCGGATCAACGCCTGATGGCGATGACTACGATCGCGATATTGTGTTGATTAGTGGTATCGGTATTACCGGTGTGAAACAGATTAACAAAGGTGAGCAGGTTATCTGTTTGCCCGGTGCAACTTTATATGACCTTGAAACTATCCTTCGTCCCTTGGGACGAGAACCCCATTCGGTGATTGGTTCTTCCTGTATCGGGGCTTCGGTTTTTGGCGGTGTTTGTAATAATTCCGGCGGCGCATTGATGCAAAGAGGTCCTGCCTTTACGCAGTTGACCCTTTATGCCCGGATCAATGAACAGGGCAAATTAGAGTTAGTCAATCATTTGGGGGTTCGTCTGGGCGATGACCCCGAAACAATTTTAAGTCGTGTTGAAAAAGGCGACTATACCGAAGATGATGTTATCAATGACGAAAGCAAACATGCTTCCGACTGTGAATATCATAACCATATTCGCGATATTGAGGCAGAGACACCCGCGCGCTTTAATGCTGACCCCTCTCGTCTTTATGAATCTTCTGGTAGTGCCGGAAAAGTGGCAGTTTTTGCGGTGCGACTTGATACTTTTCCGCAGCAAAAAAATGCCAAGGTTTTTTATATCGGCACCAATGATCCCGATGAATTAACCGAGCTTCGGCGGCAGGTATTGAAGTCTTTCAAATATTTGCCAATTTCAGGCGAATATATGCATCGCCATGCTTATGATATTGCGGCGAAATACGGAAAAGATACTTTCTTAGCGATTGAATATCTCGGCACTGATCGCTTGCCGCAGCTTTTCGCCATGAAGGGCTGGTTTGATGGTTTAAACAACCGTGTCAGTTTCTTGCCGCGTTATTTGACCGATCGGGTGATGCAATTTGCGTCCACTCTGTTCCCGCATCATCTGCCTAAGCGAATGGATGATTTCCGTGACCGCTACGAACATCATCTGATTTTGAAAGTGTCTGAAGAAGGAACTGAAGAAGCCCGCGGTTTTCTGAAAGACTTTTTCGAAAAGGCAAGCGGTGGTTATTTTGAATGTAGCGATGAAGAAGGGAAAAAGGCTTTTCTGCATCGTTTCGCCGCCGCTGGTGCGGCTATCCGCTATCGTGACGTTCATCAGGATGAAGTCGAAGATATCGTTGCGTTGGATATTGCTTTGCCGCGTAATAACAAGGCGTGGGAAGAGCATCTCCCGTCTGAAATTACCGATAAAATCAGCCATATTTTATATTATGGCCATTTCTTTTGTCAGGTGTTCCATCAGGATTATATCGTCAAAAAAGGGGAGGATTGCGCTGATATCGAACATGCTATGTGGAAAATTTTGGATAGCCGCCATGCCGAATATCCAGCAGAACATAATGTCGGGCATCTCTATTACGCCAAAGACAGCCTGAAGACGCATTATCACGAATTAGACCCGACGAATTCTTTTAATCCCGGAATCGGCCATACCAGCAAGGCCGCTTATTGGAGATAGTTAAGCTGCTATAAATATTATATTTTACAAAATAATGCTTTCTGATTGATTTCGGGGAAAAAGGTTATTCCGGCCTTTCTTTTCTTTTGCAGTGTTCTGTCAGCCTGAAAATATCTATAGTAGCTGTTTTCAGGTTGTCTTTTCCTAAACTCATGCAACTGAAAACGAGGCTTAGGGTTTAGCCTTGCAAGAATAAAAAGAAGGAAGCGAGAAAGAGAACGGTATGCGCGTTTTAATCGTTGAGGATGAGCCGACGCTTTCCCGTCAGTTGCGAACGACTTTGGAAGGGGCGGGCTATGCTGTTGATCTGGCAACAGATGGCGAAGATGGCCATTTCCTAGGCTCGAGCGAAAATTATGATGCCGTTGTCCTTGATCTCGGTTTGCCCGAAGTCGATGGTCTGACCGTTCTTGACCGTTGGCGCAAAGAAGGCCGCGAAATGCCAGTTCTGGTTCTGACTGCGCGGGATAGCTGGTCTGATAAAGTCGCTGGTCTTGATGCTGGTGCTGATGATTATCTGACCAAGCCTTTCCAGACCGAAGAATTGATTGCCCGTTTGCGGGCTTTGATCCGACGGGCTTCCGGTAATGCGTCTTCTGAATTGACGGCAGGCGATGTTCGGCTTGACACTCGTTCCGGCAAAGTGACTTTGGCGGGTGAGCCTGTCAAATTGACGGCGCAGGAATATAAGCTGCTTTCCTATCTGATGCATCATAAAGGCAAAGTTGTCAGTCGCACCGAAATGATCGAGCATATTTACGATCAGGATTTTGATCGCGATTCTAATACGATCGAAGTCTTTGTAACCCGTATTCGTAAAAAACTGGGGCAGGATGTTATTACGACTATTCGCGGTTTGGGTTATGCTTTGAACGACCCAGAGGATCGGAATAACGGCTGATTATGGCTTCCGCTTCTTCCCCTAGCGGTGGCCGAAAGCCTTTTTTTAGTCGTTTCTTTCGCCGGAAAAAAATCGAAAAAATCGGAAATCCGGTCGGAGAAAATAATAGTCAGGAGCCGGTAATACGCCCTACCGGTTCTTTGACCCGCCGGTTGATTGCTATTTCGGCTTTGTGGATATTTATCCTGCTATCGGGCGGCGGCGTAACCTTGGATCGGGTGCTGACCCAAGCCGTCACCGATAATTTTGACAGCCAACTTGATTATGTTTTGGCGGCGATGATCGCTTCTTCTGAAATTGATCCCGAAGGGGCGGTTCGACTGAATCGGCCTTTGGGTGACCAGCGTTTTTTGGAAGCCCATAGCGGCCTTTATTTTCAGGTGAGCGGTAGCGGATATGAAAGATTTCCGTCTCCTTCACTTTGGGATCGCTCGCTACAAGTTAATCCGATGCCTAAAGGGCAATTGGTGCGGACATATGATAGCGACGAATTTTCTGATGGCACTTTGCGAGTGATGGAACGGGATGTCCGCTTACCCGGTTCGTCTGTTTTATGGCGATTCCAAGTCGCTGAAATTCGTACTTCTTTAGACAATCAGATTAAAAAATTACGCCATACCCTTGTGAAAGCCTTTTTGATTTTAGGCACGGGGTTGATTGTTATTACCGTTTTACAGGTGACGATCGGATTATGGCCGCTTAGGAAATTAAGGCGCGAGATTAGTGCTGTCCGTAATGGTCAGGCTTCGCGTATTCATGACCGGATGCCGAATGAAGTCGCCCCTTTGATTGAAGAATTGAACGCTTTGTTGTCTCATAACGAGCGGCAAGCCGAAGAGGCTAGGCGACATGCTGGTAATCTGGCTCATGCCTTGAAAACGCCGTTAACGGTTGTGACTAATGAGGCGAACGCCAATAGCGATGCCTTGAAAGAAGTTGTTTTGCGGGAAGTGATGACCATGCGGCGGCATGTCGATCATCATTTGGCGCGAGCGCGGGCTATCGGACGGCGGGGCAATGCCCAAAGCCAAGCAGAGGTATGGCCTGCTTTACTGGCGGTAGAACGCGCAGTTACTCGGCTTTATCCTCATGCAACGATTGATCTTGCCGGAGTTAAGGACGCTGTTGTCAGAATAGAAAGACAAGATCTGGACGAGATTTTGGGAAATCTTATAGAAAACGCTGCTAAATATGGTCAGGGACGCGTTTTTGTTACGGTAGAAAAACAGGGTAAGCAGGTTGAAATCCTGATTGAAGATGATGGCACGGGTATTCCTGAAAATCTCCGTGGGCAGTTGTTTAAACGCGGGGCGCGTTTGGATACAGATAAACCCGGGACTGGGTTGGGGTTGGCAATTGTTCGCGATGTGGTCGAAATTTATGGCGGCGGTGTTACTTTGGAAGAAAGTGAAGATTTAGGTGGCCTATTTGTCCGTCTGGCATTGCCATCAGTAAATTAAATTCACAGTTTGATGGGATCCGCATAAAGGGTTTTGCATAGCCCTGCTATTTGTCTCTTCTGATGGAAAAATTACTGTTTTGAAACAGTATCTTTCTGCTCTCTTGGTTTTTCTGTGGCGTTAAGGTGCTTTAGCTTGGGGTAGTGTGAAGACATAGATTTTTGATACTGTTTTCTATTCCTTTGACGGGATCTTGTTGGGGAGAAAAAGGCTGTCCGATTTCTGGAGTGCAAGGCTAGCGTGTCATGACTTGAGTTGTTTGAGAGGCGACCGCTTACTGTTTACCCATTTGTCTTTTGAAGTGAAGGCTGGGGAGGCCGTTTTAATAACGGGGGCAAATGGTATTGGCAAAAGTAGCCTTTTGCGTCTGTTGGCGGGTTTTCTGAAACCTTTTTCGGGTCATGTTGAAAAATGGGGTCGGGTGGCTTTTGCGGATGAGGCTTTGGCAATGGATCGGCATTTGCCTTTAGAAAAAGCCTTGGCTTATTGGGCGGCTTTAGATGGCGTTTTGGGCGCTGAAAAAGAAGCCATGGTGGTGATGGCTCTTGATAGATTGGCGGATTCACCTGTCCGTTTGCTCTCGACTGGGCAGCGTAAAAGAGCTGTGTTGGCGCGTTTGTTGGCAAGCCAGGCTGCTATCTGGTTGTTGGATGAACCGGCAAACGGGCTTGATGCGGCTTCTGTTAGGGCTTTGATCGAAATGATAGAGCATCATCGCCAAAAGGGGGGGATTATTTTGGCTGTTAGTCATCAAGGGCTTGATATGGCTGATTATAAAATCTTGTCTTTAGAAAATTTCGTAGCGGAGTCTGGCCAGTCATCAGGTCTCTTTGACCTTTTGGATGAAAGTCATTTCTCTTGATCCGGCTTCTTTTGTTGATTCGTCGGGATTGCTCGATTTTGATCGGGGCAGGGGTGTTTCTACCTGTCTTGTTTTTTTTATTGGTTGCCGTTCTATACCCTTTCGCGGTGGGCAGTGACGCTATAATTTTATCGCGTACTGGTAGCGGAATATTATGGGTTGCCGCTCTGTTAGCTTCTTTGTTACCCATTGACCGTTTGATTATTCCCGATGTCGAAAATGGCTTTTTCGATTATTATGCGGTGCGCGGAATTAGCGAAGAATGGATAGCTGTGGCGCGTATTATCGCCCATTGGGTAAGTTTTGCTGTCCCTTTAATGGTGGCGTTGTTACCCGCCTCGGCTTTGCTATCTTTGAATTGGTCTGTTTTCTGGAAATTGGAAGCCGGATTTTTATTGTCTACTCCTGGGCTGGCCTCTTTGGGGGTTATGATTGCTGCTTTGACGGCAAGGATAAAGTCCGGAAGTGGGTTGGCTGCTTTACTTTTATTGCCTTTGGCTGTGCCGCTCCTCATTTTTGGCGCAGGGGCTGTTGATGGCCATCAGCCTGGGGCCTTCCTATTATTGGCGGCTTGTTCGTTGTTTTTGCTCGCTGTCGCGCCTTTTGTCATCGGTGCCGCTTTGCGCGTCGGACAAGATGGGTAAAAGGCTTACTGTATCGATTTAAGGCAGGCTTTGTGATTGATGAAGTCGAGATAGAGATTTCCTTTGTCTAGGCTCAGGACCCATTGATTTGATTGCGGAAATCTGATTCAGGCTCTGTGAGGAGACTGAAGATGAGTGACCTGTATTGGCTGACCGAGGAACAGATGGATCGTCTGCGGCCCTTTTTCCCGAAGAGCCATGGCAAACCTCGCGTTGATGACCGTCGTGTGTTGAGTGGGATCATTTTCGTGAACAGAAATGGTCTGCGCTGGCGTGATGCGCCTCTGGAATACGGTCCACACAAGACGCTCTACAACCGCTGGAAGCGCTGGAGTGCTATGGGGATCTTCATCCGCATGATGGAGGGATTGGCTACTGGCAAGGCAGAGCCTCAGACAATCATGATTGATGCGACCTATCTCAAGGCACATCGCACGGCTTCGAGCCTGCGGTTAAAAAAGGGGGCCCAGGCCGTTTGATCGGGCGGACCAAAGGCGGGATGAATACGAAGCTGCATGCTGTCACTGACCGGAACGGACGTCCGCTCGACTTCTTCATGACAGCAGGTCATATCAGTGATTATACTGGTGCCGCTGCCCTTCTGGACAGTCTGCCATCAGCCGAATGGATGCTGGCAGATCGGGGCTATGACGCTGACTGGTTCAGAGAGGCCCTGGAGGAGAAAGGGATCAAACCCTGTATTCCTGGTCGAAAATCTCGTTCAAAACCGGTCAAATACGACAAACGGAAATACAAAAGACGCAACCGTATCGAGATCATGTTCGGCAGGCTCAAAGACTGGAGACGGGTCGCAACACGCTATGACAGATGCCCGACCGTCTTCTTCTCGGCAATCTGCCTCGCTGCAACCGTCTTGTTCTGGCTATGAGTCCTGAGCCTAGAAAGAAGGGAATATCTTCTTTGTTTAATGAGGCAATTATAGACGGCAGTTTTTCTGCATTCCGCCTATAAATTTCCTTTATCGGAATTTGAAACTGCAACGGAACTGATTGTTGTTGCTCTATTCCTGTAACGGTAAAGGGAGGGATAGAATCTGGAGAAATTGTCAGATTCCCCATCTTTGTTACAGTAAGAGAAAATTTTTCAAGCCCTTTAAATTTTTGGATAGCTGGATAATAGACATTTTCAATAAGGTTGAGTTCTATGCCCCAGTTTTTAATATCTCCATCTAAAAAATAATTCCCTATAAGCATTTGACTGCAAGTCAATAATATACCGTTAATAGGTGGTAATGGATCCTGTGTATTTTTGTCTTGAAAGAAATTTTTCTTGCATATTTCCAGTTGTTTATTGGCTTCTTGAAAAGCACCTTTAGATTGATAGACTTCAATCTTAGCAAGATTTTGAACGATATGCGTGCTTTCTTTCGAAGTAGCCATTTTTTGAATTAGGGCCTGTTAGTGCTTGATCCAGTCTGCTGCGGCAGCGATGTGGATGACCGCGAGGAACGAGGTTGCTGTTTTTTCGTATCTGGTTGCGACAGCGCGCCATTCCTTGAGGCGCGCCCAGAGGTTCTCAACGAGATGCCGACACCGATAGGCCCATCTTGGTCAGGCAAGCGACCCATCCCGTCGTTTCGCAGGAATAGCCGGTCGGGCTCCCATGTCCCATATCCGTTCACGAAAGGCGTTCGACGCGTAGCCTTTGTCCGCCACGACCCACAGGGGAATGGTGGGAAGATTGTCGAGCATGGCTAACGTCAGAGGCAGTTCATGAGCCTGTCCCGGTGCCAGCGCAAAACCGAAGGCTTTTCCATGCCCATCAGCGATTACGCAGATTTTTGTGCCATAGCCGCCACGAGAGCGCCCAAGTGCTTCACGATGGTCTCGCTCTTCGAAAGAGGCCCCTTTTTTTGGGATCCCGCCGCCTTGTGGTGAGCCCTGATATTCGTACCATCCAGAAAAATCATTCCGAACGCTACTCCGTACTGTTCCTGAACCAGTTTGAGCAGGCGTTCCCATACGCCCAGTTTCGCCCAGCGAATGAAAAGTTGGGCTGCCCGCCACCACGGACCCAGTTCAGCGGGGATACTCCGCCATTTCGCGCCATTCTCATGACGCCAAAAAATCGCTGATATCGTGCGCCGCAGATCATGTGGTGGCGTCTTGCCTTTCGGACGAACCGTCTCAATCAGAGGTTCCCAAATCGCCCATGTCTCGTCCATAAAAGTGCCTGTTCCGTCTCCTTCTTCCATCTCTATAATATGGAAAGAATTTCAAGATCTAACAGACCCTAGGGATGTCTCTCCTTCGAATAAGGCTTGTTGAAGCTCTTCGCCACTAGGACGTAATTCTATGCCTTCTTGAAGCATTTCTTGTTTATATTGCCTGAGAATCTCGATCAATTTTGGAGAGACGAGAGGCTTGTCAGCTTTCAATTCTGGCAAGAAAAAGCTATGTATAACACAAATTAGAATAACAAAATTATATTTTGAAAACATATCGATTCCTAAATTAAAAAGGATTTTTTACATTTGTATCTACTTTATTTCTATTATATTTTTCGAAATCTTTGTTTAAGTGAATCCCCAATGTTATTCCGTTCCCAAACAAGTGACTGTAATTTAATCCAGCTTCTTTTTCATTATTATCATTTTTAAAATTGGCTCCTATTGAAGATCCGTTCGCAGTTTTGAAATTTCCATCTACAGCCATATTGTAGCTATTGTGAGCCCCCCTCCAGATGCATTTATATTAAGATTGGGGCTTTTAAGGTGAACTCCGGCCTCTATTGATTTTATTGGTTTTAAACCTTTACCGCTGATTCCTGCATTAAAATTAGGATCATCGTCTATTGGAGAATATCCACTCATTTTTTGAGGATCGATGTAACGGGGGGAAGAAAATGTATTACTATTCGTTATTGTTGAATTAGCATTTTTCGATAAGAGATCTCTCTGTGATATAGGATATCCAGTGTTTCTATCCGTAAGTGTAAAATACTGATTTTTTTTCAGTAGGATCGCCATATATTTTTAAAATATTTGGATATTGATCGGGTGAAAGTAATTTTAACCATGAAAATGAAAGAATGCTATTGGGAGTGTTGTTGGTAATATTATCGGGCAATAAATCCAATATTGCAGATCTAAGTCTTGGTCTATTTTTTGATTCGTTATCCAATTCTATGCTCCATATTATAAATAAAAGTGATATGGAGTGGTGTATCTGTTTTTATCCAACAATTATTATATGAAATAACATTTTTATTTGAGATATTGGTTCGTGCGGTGATGGGTGGCTGAACTGGCTTGCCTTTTTCCTATTCTATTGAGATAGCCAATTTTGTGACTTGGATTTTTGCATTTCTGGCCGGATTGGTCGCGGCCTTGGGATTACAGCCTTATAATCTGTGGGGATGCAGTCTTGTGGCTGTGGCTGGATGGCTGGCCTTATTGCGACAAACCCAAAAGACTTGGCAGATTTTTGCCCTTAGTTGGCTTTTTGCTTTCGGTTTTTTCTGGTTAGGGCTGGACTGGATTGCGACTTCTTTTACCCATCAGGCTGCGATGCCATCATGGTTGGGTTGGGTCGCAGTGCCTTTATTATCCTGTTATTTGGCCTGTTATATTGCGCTTTTTACTTTGCCCCTTCGTTTCTTATGTCTTTCTTTCCAGCGAGGCAAAAAGAGAGCGGATTCTTTTCAGTCGTCTGATGTGACTTTGGACGGCGCGGATTCTGGAGATGTCGATGCTATTCCCTCCCGTCTTTTTCCCGTGGGGAATGAGGCGGTAGCGCGTGAAAGGAAGATAAAAAGCCGTTTTTTTGTTGGATCTGCTGCTTTTTGGTCTGTGCCTGTTTTCAATATATCTTTGTCACAAAGACCGCTTTGGCGTTTGACGCTGGCCTTGGCTGGGTGTTTGGCATGGGGCGAATGGATAAAATCATGGGTTTTTACTGGATTCCCATGGAGTCCACTAGGCGCTATTTGGCTGAATGTCATGCCCATAGCCCATATCGCCCGATGGATCGGGAGTTACGGTCTGTCGGCTCTTGTGGTTATTGCCGCCGGTATCGGCTTATCTTGTTATGACGGCATTAAATCAGCCATAGAGAAAAGACAGGCGAGACAGGCTATCCGGTCGATCCTTCCGGCGTTTTGGATGGCTTTACCTTTTTTAGGATGGGCGTTGGTCGATGGTCATGACATCCATTGGCAAAAATCAGAGCAGCCGCCTGCTCATGTGGTGATTGTCCAGCCGAATATCCCGCAGGATGAAAAATACGATCTCCGTTATAAATCTCGTCATGATGCTATTTTCGAGAAATTGTCAGGGAAGGGTGATCCCCATCATCCCCGCCTGATTTTATGGCCGGAAGATGCGGTTCAAAGTTATTTGGAAGAAGAGCCTTTGGCACGGGCGGCTTTGAGCCGTTTATTGGGCAAAAATGATCTGTTGTTGACGGGGGGCGATGCTTTGATCCCCGATAATTCCGGTCATATCGCTTCGGTTCGGAATAGTTTATTTGTCCTTGGTGCCAAGGGCGATATTTTAGACCGCTATGACAAAGCCCATCTGGTGCCTTTCGGGGAATATATGCCTTTTCGGAAATGGGCGGCCTATGTCGGATTAGGGCGGTTGGTCGCTGGTGATATAGAATTTACCGAAGGGGCGCAGCCGGAAAGTCTTGATCTATCACCTTTTGGTCTGGTCGGGATTCAGATTTGTTATGAAATCGTCTTCTCCGGTCGGGTGGTTGATCGCGTTCATCGTCCCGATTTTATTTTTAATTTATCCAATGATAGCTGGTTTGGTCGATCGGGCCCGCCTCAACATCTGGCACAAGCGCGATTGCGGGCGATTGAAGAAGGTCTGCCTATTGCGCGGGCAACTTCTACTGGTATTTCTGCGGTGATTGATGCCGAAGGGCGTATCCTGCAATTTTTACCGGAAAATACCGAGGGACGGCTTTTGGCGGTGATGCCGAAAGCGTTACAACCAACCTTTTTTGCCCGCCACGGCAATTTGATTAGTGTGCTTTTTGCCACGGCTCTGTTGCTCATTGCCCTGTTTGGGCGTATTAAGTTACGCTAGTCTTGATATAAGGAAAGATTTATATCTTTATATTCTATCTTTCTATAGCGTGTCACTTTTAGATGGGGATTGGCTTTGGGGAGGAAAAATCTGCCATAAAGGGCGAGATGTTTATTTTTTCCTCTTTCTGATCGGGAAACTGTCAGGCCAGCTTCATTTTTAGGTTTAACAGATAAGGAAAATCCTTTTTCTATGCGTAGCAACTACCTGTTTACGTCCGAGAGCGTGTCCGAAGGCCATCCCGATAAGGTTGCTGACCAAATTTCTGATGCCATCGTCGATTTGTATCTTTCCCGTGACCCGGAAGCCCGCGTCGCCTGTGAAACGCTGGTTACCACGCAGCGCATCATTATCGGCGGTGAAGTCCGTTCGGCTGTTCCGGTCAGTGAAGAAGAAATCGAAAAGACGGTTCGTGAAACCGTACGTGAAATTGGTTACGAACAGACTGGTTTCGATTGGAAAACGGCTGAATTCGCTAACCATCTGCATGCGCAGTCTGCCGATATCGCCCAAGGTGTCGATGCCGGTGAAGATAAAGACGAAGGCGCGGGCGATCAGGGCATTATGTTTGGTTTTGCTACCGATGAAACGCCTGACTATATGCCGGCGACCCTTTATTATGCCCATCGTATTCTGGAACGTCTGGCTGAAGACCGTCACCAGAAAAAAGTCGATTTTCTGGAACCTGATGCCAAAAGTCAGGTGACTTTGGTTTATGAAAATGGTGTGCCAGTCAGAGCTTCTGCTTTGGTTCTGTCCACCCAGCATAGTCCAGCTTTGAGCTCGAAAGAAGGTCAGGCTAAGCTGCGCGACTATGTCAAATCGGTTTATGAAGATGTTCTGCCTAAAGGCTGGATGCCGGATGACAAAGCCATTTTCGTTAATCCGACCGGCTTGTTTGAAATCGGGGGTCCTGATGGTGATGCCGGTTTAACGGGTCGTAAGATTATCGTTGATACCTATGGCGGTGCAGCGCCTCATGGTGGTGGTGCTTTCTCCGGTAAAGATCCGACCAAGGTCGATCGTTCTGCCGCTTATGTTGCCCGCTATCTTGCCAAAAACATCGTGGCCGCCGGTTTGGCCAAGAAAGTGACGATCCAGCTTTCTTATGCCATCGGTGTTTCTGAGCCTCTGTCACTTTATGTCGATACCCATGGCACCGGCACGGTTGATGAAGCCAAGATTGAAGAAGTCTTGCCGAAGCTGATCCGTTTGACCCCGAAGGGTATTCGCACCCATCTGAAGTTGAACAAGCCGATCTATAAGCCGTCTGCCGCTTATGGTCATTTCGGTCGTAAAGCCGATGGTGATTTCTTCCCGTGGGAAAAACTCGATCTGGTTGATAAGCTGAAAGCGGCTTTTGCCTGATCTTGAAATTGTCTTTTGACATTATCCTTTGAAAAAGCCTGTTTCCTGAAAAAGGAGGCAGGCTTTTTTGCAGGTTAGACTTTGCGTGAAGCACTGATTGCTTTTTGGCGGCGGCGCTGCACTGAGGAGCCTAGGCTCAGGACCCATTGATTTGATTGCGGAAATCTGATTCAGGCTCTGTGAGGAGAGTGAAGATGAGTGACCTGTATTGGCTGACCGAGGAACAGATGGATCGTCTGCGGCCCTTTTTCCCGAAGAGCCATGGCAAACCTCGCGTTGATGACCGTCGTGTGTTGAGTGGGATCATTTTCGTGAACAGAAATGGTCTGCGCTGGCGTGATGCGCCTCGGGAATACGGTCCACACAAGACGCTCTACAACCGCTGGAAGCGCTGGAGTGCTATGGGGATCTTCATCCGCATGATGGAGGGATTGGCTACTGGCAAGGCAGAGCCTCAGACAATCATGATTGATGCGACCTATCTCAAGGCACATCGCACGGCTTCGAGCCTGCGGTTAAAAAAGGGGGCCCAGGCCGTTTGATCGGGCGGACCAAAGGCGGGATGAATACGAAGCTGCATGCTGTCACTGACCGGAACGGACGTCCGCTCGACTTCTTCATGACAGCAGGTCATATCAGTGATTATACTGGTGCCGCTGCCCTTCTGGACAGTCTGCCATCAGCCGAATGGATGCTGGCAGATCGGGGCTATGACGCTGACTGGTTCAGAGAGGCCCTGGAGGAGAAAGGGATCAAACCCTGTATTCCTGGTCGAAAATCTCGTTCAAAACCGGTCAAATACGACAAACGGAAATACAAAAGACGCAACCGTATCGAAATCATGTTCGGCAGGCTCAAAGACTGGAGGCGGGTCGCAACCCGCTACGATAGATGCCCGACCGTCTTCTTCTCGGCAATCTGCCTCGCTGCAACCGTCTTGTTCTGGCTATGAGTCCTGAGCCTAGTGATCGTCAGGCTGGAGGCCATAAATATACCTGCATCAGATTTTAGGATTTAAAATAAAGCAGAAGCAGAGGTATTATTTTACCAGTTACTAATGCCCCTATCTCGCAAATCTTAGGGTATATTTTGTGCAGTCTTATACAAATTATAATAAATTCATTGTGCTTTGTAATAAAAAAAACAACTATTTTGAATATAAATATAATATTTTTTATCTTTTATTTTTAATAATTTACAGAAATTTATACCAAATCTCTTACCAATAAGACGTTCAAAACAGAGTTATTAGCTTTTAAAAAAGCTATCATTATAAAAAAGGCAGGTGGGAACCTAAATTCTCCAACCTGCCTTTGTCATTTCACATTACTTTAATCTATGGTCGAACAGCTACAACCGCATCAATTTCAACAGGAGCATTTAACGGTAAAACAGCCACGCCGACAGCACTACGGGCGTGAACACCAGCATCTCCAAAGACTTTCGCCAAAAGTTCAGAGGCGCCATTCACGACTTGCGCCTGCCGCGTAAAGGAAGGGGCTGAATTCACAAAAGCATTCAGCTTTATAATCTTTTCGACCCGATCAAGACTGGTAAGGGCAGCTTTCATCTGAGCCATAAGCATAATGGCACAGCGTTCAGCCGCTCTAAAACCGTAAGCTTCATCACGGTCTTCACCGAGGCGGCCTGTCATTAGCTGACCTTCAAGGAAAGGAAGCTGGCCAGAGATATGAAGCAAGTTACCCGCCAACACTGTAGGAGCATAAGCTGCAACAGGGGCTGCCGCTTCAGGGAGAAGGATGCCAAGTTCGGCAAGTCTGGTTTCAATAGTCATGAAAGAGATTTTTGTCTTATAGGGGGTAAAGGTCAAGCCCTGAAAGCACAGTTCATTTAAAAACAATCCGTTTTTATCAACAAACTGAACAAACACATAAATTATCGTTAGATTTGATAGATTTTTTTGGTCTAAACTGGCGCTATAATCAGAAAAGAATGGATGCGAATAATGGCTTCGCGTATTTTGATAGTTGAAGACAACGAATTAAACTTAAAACTCTTTTGTGATCTATTGCGCGCGCATCATTTTGACGTAGAGCCTGTAAGAGACGGGCGAGGAATGATAGCTCGCGCTCACAGTTTTATGCCAGATCTTATTATTATGGATATTCAACTACCCCATATTAGTGGGCTAGAGCTGATCGGGCAGATTCGAAAGACAAAAGAATTATGCCATATACCGATTATGGCAGTTACAGCCTATGCCGCACCAGAGGATGAACAAAAAATCCGTCAAGCTGGGGCAACCGGTTATATCGCGAAACCGATTTCTGTAGTTCGATTTCTCGAAGCTGTAAAAACTTTAATCTGATCGTAAAAGACAGAAAACCGGTCTACCCTGCCAACCACAAGCGGGTCACCGCAGAATAGCTGCCAAAAGGCAGGCCCGGTTTATCTGGGAATTTCTAAAGAAGCGCTTTAAAAAATTATTTAATTTTAGCTTCTTTGAATTCGACATGCTTCCGGACAACCGGATCATATTTACGAAGGCTCATTTTTTCGGTCTGGTTCCGCGGATTTTTGCGGGTAACATAGAAAAATCCGGTGTCTGCAGAACTAACGAGACGAATCTTAACTGTAGTCGGCTTAGCCATAGTGAAACCTTTTGCACCTAATTCTAGAAAAAATGCTAATCGCATCAGGCGCCAGACATAGCTGCCGATCACCTGTAAAGTTGGCTTACTGCCCCTAAAAGCAGGGAAAAGTCAAGGGGTATATAGCTTTCTGACCGATCAAGGGCAAGATGAACCCTGATTATCGGCAAAAATATAACAGGCTGGTCGCTCAGAACCAATAAATTACAAAAACAAAGTAAATTCAAAATAAACAATTGGGGGCTCACTTTTACAATAAGCAAGCCCTCAAATTTGTTTGAATTTTAGAGAATATATTTACTCAAGTCAGAATTTTTGGCGATGCCAGATAATCTTTCATCGACATATTTCTTGTCTATTTTTATTTCTTCACCGTGCATATCTTCAGCATTAAAGCTGATATCTTCCAACAGCTTTTCCATTACTGTTGATAAACGACGAGCCCCAATATTCTCGACCTCGCTATTTACCTCGGCCGCAATATGCGCCAGCTGGCGGATACCATCTTCTTCAAAATGAAGAACAACATTTTCGGTGCCAATCAAAGCTCTATATTGTTCGACCAAAGACGCTCGGGTCGAAGAAAGAATGCGGATAAAATCATCTTCTGTCAAAGCAGACAATTCAACACGAATAGGCAGACGCCCCTGTAATTCCGGCAAAAGATCCGAAGGCTTTGCAACGTGGAAAGCACCAGATGCAATAAACAGAACATGGTCGGTTTTCATCGGGCCATATTTTGTCGTAACCGTTGTGCCTTCCAACAAAGGCAAAAGATCGCGCTGCACGCCTTCACGCGAAACAGAGCCCCCTCGAACATCGCTTACCGCAATTTTATCGACTTCATCCAAAAAGACGATACCATTTGCCTCGGCATTCGACAAAGCGATCCGACCAATTTCATCCTTATCAAGACGGCGATCGGCTTCTTCGTCAATCAAACGACGCCATGCTTGACGAACAGGCAAACGCTGACGCTTTGTACGATGCCCCTTCCCCAACATATCACTCAGACTAATCATGCCGACTTGTCCGCCCATACCTGGAATTTCCACTGGCATAGAGGGGGCTTCTTCTAGCTCAAGTTCGACTTCTCTTTCGTCAAGATGCCGATCTAAAAAGCGCTGACGGAAAGTCTCACGTGTGGCTTCACTGGCGTCCTTACCAACCAAAGCATCCAACAAGCGCTCCATTGCCGCTTGCTCTGCTTTTTCACGCACTAAAGCGCGCTGTTTCTCGCGCTCCAACCGGACGGCTTCTTCAACCAGATCACGACCAATCTGCTCAACATCGCGGCCAACATAACCAACTTCGGTAAATTTAGTCGCCTCAACTTTAATAAAAGGCGCATTTGCCAATTTGGCTAAACGACGACTAATCTCGGTTTTACCGCAGCCCGTGGGGCCTATCATCAAGATATTTTTAGGATTAACTTCATCCTTCAAATGCTCGGGCAAATTTTGTCGCCGCCAACGATTCCGCATAGCGACAGCAACAGCACGTTTTGCTTCTTTTTGTCCGACAATATGGGCATCCAAAGCCTCAACAATGGCTTTGGGCGTAAGGGCATCAGTCATACAATCTTTTTCCAGCAAGAAGAATTAAACTCGACTTTCAAGCGTCTCAATGGTCACCTGATCATTGGTGAAGACACAGATATCGGCAGCGACCGCCAGAGCCTTACGAGCAATGACTTCGGCATCTTCTTCGTAATCAACAAGAGCGCGCGCCGCAGACAATGCAAAGTTACCTCCAGACCCGATAGCAGCAATACCGCCGACAGGTTCTAAGACATCCCCATTACCTGTTAATACCAATGTCACCTGATCATCAGCCACAATCATCAAAGCTTCAAGATTCCGTAGATATTTATCGGTGCGCCAGTCTTTAGCCAATTCAACAGCTGCTCGTAACAGCTGCCCATTATGACGTTCCAGCTTGGCTTCAAGTCGCTCGAATAATGTAAAAGCATCCGCCGTGGCGCCAGCAAAGCCGCCAATAACAGAGCCATCTCCCAAGCGGCGTACTTTTCGGGCATTCGGCTTCATCACCGTATTGCCCATCGAAACCTGACCATCACCAGCAATGACAACACGTCCATTCCGTCTGACAGAAAGGATCGTTGTGCCATGCCAGCCTATTTTATCTTCACTCATCACCCAATCCCTTGAAGACTTAAACTTTTAGAAAACAATATGGGGAGATAATAATAAATCGCAATCGCTGAGCGCCCGGTTAAGAGAGATTAACAATCTCAAGACACTCTCATTTCTATGGAGATTCCGCTCTCAATGAAGCGCTAAAAGCAGAATATTGCCTACTTTTCTTCTCAAAATCATAGAATCAGCCTATCGGCCTATAAATCGAAAAAATGGCTTAAAAATCACGCTTTCCGATAAAAACATGAGAAAATTGTTAAATTCGGAGGAAAAATTCATTTTTTCTTGCCGCATCTGGCGAATAAGCGCTTTGGGCAATATTGCCATTTTTGTCAGGGAATATAAGAGTCACCAGCTTAAGACGCTGCGATCCCCGCTCGTCTAGTTGCTCAAAGGAAGGACAGGATGCCGGAATTAAGATTATAGACAAGGCTCCCATCTTTCTTAATGTAGCGACCACCGCCGGGATTCATTTCTGACAGGAATGAATCTTAAAAATTTTTCTATTTATTAATGCCATAGGATCACGACATGAACAGCAACGATCTGGTTGACCGGATTGCCTCCGGTCAGGGCCTCACCAAAACGGATGCCAAGAAGCTTGTAGATGCCGTTTTTTCTACCATTGTTGACGCTGCTGTCGCTGGAGAAGAAATTGCCCTGAACGGCTTCGGCAAATTCAAGGTAAAGCATAGTGCTGCCCGTAAAGGCCACAATCCGGCCACCTTACAGGAAATCGAAATTCCGGCTTCAAATCGTCTGACCTTTACTTCAGCCAAGGCTGTTAAAGATCGTTTGAACGCCTAATTTCCTGAAGACACGACCAATTGGCGCGGTAGCAGACTACTGCGCCAATTTTTGCCACTCAAAAATCCAATATTATCTTCTTCCGACCAAAATCTTTTCTGTGTAAGACCCAGCGATAAAGGTCTGAATAGACTTCCATTTTTACACAAAAATTTCGGCAATCCGAACCAATAGAGAGATTATTTTTAGGACATCTCTCTGTTTACCGTTATATTCGCCGGCATTGCTTGATTACTCTTCCTTCAATCCGGAAAATTTATTAATGCGGAATCTGCTTTTTTCTTCCTGTTTTCTAATGGCTTGTAGCACGGCCTTTTCACCGGCCAATGCGGGCATTACAGATCCGCCCTCTTCTTCTTTTACTGTTTCAGGCAGCCTCAGTCTTTTTTCAGATTATCGTTTCCGAGGTCTATCACGCAGCAATAATCATCCAGCCGTACAAGGCACTGTTACCGTAGCCCATAAAAGCGGTTTTTATGTTGGAGCATGGAGCTCTAATTTGGCTGGCTGGGGAAAAATGGGTGACAGCAAAATGGAACTCGATGTGTTTGGTGGTTATCGCCATACACTCGGCGCATTTACAATGGACGGTGGCGCAATCGGCTATATCTACCCAGCCGGAGGTGGCGGAACAAAAAACAACTATTTTGAAATTTACGGAAGCGCCAGCGCTCTTGTCGGGCCTTTCACAGGAAAACTTGGCTTTAATGTAGCCCCGCCTCAACATGCCTTAGGACGTTATGATCTGGTTTCTCTTTCCAAACATGGCGATCACAGCAATGTCTACGCCTATGGTGAAACCGATTTTGCTATTCCACGCACAGCTGCTGCCTTACATGGCCATATCGGGCATACAAACGGAGATGCTGGTTTTGGGCCTAACTTTGCCAGTTTATCCCCAACAGGAGGCTATTGGGATTGGAAGATCGGTGCAGACTATACTTTTGTAAAGCATGTGAAGGTCGGTGTCTGGTGGTCTGATACCAATATTGATAACAAAAAATTCAAATCTATGTGGTCATCTACAGATAAAGGTTTAGGACGCAATGGATCTATAGCAGGAAGCGCCGCTATCTTTTCTTTGACCCTACTTCTTTAAAGTCTTTTTATTCAAAAGCCATTTTAAGGTAGTCAAGTCTCTAAAATTCAATGATTAAATCATCGGTCTAAAAATCATCTGACGGCTGGCTACTGCAGAATTTTGACAGCAGTAGCCAGAATAATAAAATTCTACTATTTAAATGTTGATCTTATTACATTGAATAATTAATTAAAAATTACTTAAATAAAAATGATTTAAACAATAATTTTATTTAAAAAGAATTGAGTAAATAAGAATAATTTTTCTATAAAATATTTTTTGTACTTAAAAAATATACAATATTGAGAAAAAACACAAAGAGCGACTATCGAATAGGTCGAAAGTCGCTCAATCTGTTTTTATTTAGGCTGAAAAGAAGACAGCTAATAGAATTAGTTTTCTTCTTTGGCTTCTTCTGCAAGGATAATCAGCCCTTTTTCGTTGATTTCAGCAAAGCCACCAGAAATATGAAACTTTGTTTCGATCTGATGTTCACTGCTATAAATAGCCACTTCGCCATCCCGGATAGCTGTCATGGTAGGCATATGACCTGCCATAACACCAAGATCGCCCTCGGTTCCGGGAACAACGACCATAAAAGCATCGCCGGAACGGGCAAGACGTGAAGGTGTTACCAGTTCATAATGAAGCTCAGCCATTCTTCCTCACTATCTCCGCCCCTTTCTATACAGAAAGAGGCGGTTTTATTTTTCAGCAACTAGGCTGCTTCTGCGGCCATTTTTTCAGCTTTAGCGACAACTTCATCGATAGAGCCGACCATGTAGAAAGCATTTTCAGGCAAATCATCATATTTACCATCAATGATTTCACGGAAGGAACGAACCGTATCTTCAACCTGAACAAATTTACCAGGCATACCGGTAAAGACTTCAGCCACATGGAAAGGCTGTGACAGGAAGCGCTGAATACGACGAGCACGACCAACGACCTTACGATCGTCTTCGGACAATTCGTCCATACCCAAAATGGCAATGATATCCTGCAGGTTTTTATAACGCTGCAAAATTTCCTGCACATCACGAGCCGTCTGGTAATGCTCATCACCAACGATGCGTGGTTCAAGGTTACGGCTGGAAGAGTCAAGCGGATCGACGGCGGGATAAATACCCATTTCCGAGATCGCACGGCTCAACACGGTAGTCGCATCCAAATGGGCAAAACTGGCGGCAGGTGCAGGATCGGTCAAATCGTCGGCCGGAACATAGATGGCCTGAACCGAGGTAATGGAACCCTTCTTGGTAGAAGTAATACGTTCCTGCAACTGACCCATGTCAGTAGCCAAAGTTGGCTGATAACCCACGGCAGAAGGAATACGACCCAACAGAGCAGAAACCTCTGCACCAGCCTGCGTGAAGCGGAAGATGTTATCCACGAAGAACAACACGTCTTGACCTTCTTGATCACGGAAATATTCCGCCATCGTCAGACCAGAAAGAGCAACACGAGCACGGGCTCCCGGCGGTTCGTTCATCTGGCCATAGACCAAGGCCACTTTGGAACCTTCAGAAATCGCATTACCATCTTTGTCACTGGCAATAACGCCAGCTTCAAGGAATTCATGGTAAAGATCGTTACCTTCACGGGTGCGCTCACCAACGCCGGCGAACACCGAGAAACCACCATGGCCTTTAGCGATATTGTTGATCAGTTCCTGAATCAACACGGTCTTACCAACACCGGCACCACCGAACAATCCGACCTTACCACCTTTGGAGTAAGGAGCCAGAAGATCGATAACCTTAATACCAGTCGTCAGAATAGCTATATCCGTGCTCTGTTCCGTGAATGCCGGAGCATCAGCATGGATCGGCATAGTCTGCTTGCTGCCGATCGGGCCCCGTTCATCAACAGGACGACCAACAACGTTCATGATACGGCCAAGCGTTTCAGGACCAACCGGAACGCGGATTTCACTACCGGTATCAACGACTTCTTGGCCACGAACCAAACCGTCCGTTGTTTCCATGGAAATAGTACGAACAACATTTTCACCCAAATGCTGAGCGACTTCCAGAACAACCGTAGCATCCTGGTTTTGGGTTTCAAGCGCCGTAAGAAGAGGAGGGAGTTTCTCTTCAAAAAGCACATCGACGACCGGACCAATGACCTGGCTTATCCGGCCAATATTCTTTTTACTAGAGGCAGTAGCCATAATATTTTCCTTGCCAGTAATTCTTTAATTACAACGCTTCTGCGCCCGAAATAATTTCGACCAATTCAGTCGTAATCGCTGCCTGACGCAAACGGTTATACTGAATAGACAGTTTGGAAATCATTTCACCGGCATTACGGGTGGAATTTTCCATGGCCGACATACGACTACCCTGTTCGGACGTCGCATTTTCAAGCATAGCCTGATAAATGGCGACGGCGATGCTACGGGGCAGCAATGTCGACAAAATGGTTTCTTCATCAGGTTCGAATTCAATCGCACCAGAAGAAGCATCATTGGCTGCAGCCTGATTTTTCGTATCATCACCTTCAGGTGCCGCAGGGATAATCTGCGTTTCTGTCGGTACTTGTGACAGCACCGAGTGATAATGCGAAAAGAACAGATGGGCGACGTCAAATTCACCCGCATTAAAACGCTGGATTAAATCCTGAGCGATTTTCTGCGCATTTTCGAAAGTAACCGGCGAAGTCTCTTCACGTTTAGTTTCGTGAATAGTCTTGCCAGGGAAATTATTACGAATTACCGGCGCATTTTTAATACCGATAACATAGAATTGAACGGTTTTACCCGCCGCTTCCAACGCCAAAGCCCGATCCCGAGCCTGACGGTAAATATTGGAATTAAAACCACCGCATAAGCCGGCGTCAGAAGACGTGACAATCAACAAATGCGTCTGGTCTTTGCCGCGCCCGTTTAACAAGGGCAAAGCATTAGGCGTTCCGGCTGCTCTCGCAGCCAGTAACGACATAACTTGCGCCATTCGCTTTGCATAAGGACGAGCTGCTGCAAGACGACTTTCTGCCCGCCGAAGCTTGGCAGAAGCCACCATTTGCATAGCCCGAGTGATCTTACTGATCGACTTAATCGAACTGACGCGCGTTTTTAAACTTTTCAGGCTGGGCATAGTGTCCCCACTCCTGTCATTGACACATCAGAATTAGGCGAAAATTTTGGCAAAGTTATCAAGCGCAGCCGTCAACTTCGACTTGGTTTCGTCAGAGAAGTCGCCCGTCTCACGGATCGTCGCCAGCAAGTCGTTATGGCTTGAGCGCATATAGCTCAGCATAGCTTCTTCATAGCGGTTAACATCCGCGACTTCGATACCATCGATATAGCCGTTCGTACCCGCGAAAAGGGAAACAACCTGCTCTTCAAATGGCATCGGATGGAACTGCGGCTGCTTCAGAAGTTCAGTCAAACGTTTACCACGATTGAGCAACTTCTGGGTGGACGCATCAAGGTCAGAACCGAACTGAGCGAAGGCCGCCATTTCGCGATACTGAGCCAATTCCAACTTGATAGAACCAGCAACTTTTTTCATGGCCTTGGTCTGCGCAGCAGAACCCACACGGCTCACGGAAAGACCGACGTTAATAGCTGGGCGAATACCCTGATAGAACAAATCGGTTTCAAGGAAGATCTGACCATCCGTAATCGAAATCACGTTCGTCGGAATATAGGCAGAAACGTCACCGGCCTGAGTTTCAATGATCGGCAAAGCGGTCAAGGAACCTGCACCCATTTTGTCGCTCATCTTTGCTGCGCGTTCTAGCAAACGCGAATGCAAATAGAAAACGTCACCAGGATAAGCTTCACGGCCTGGCGGACGACGCAGCAACAAGGACATCTGACGATAAGCAACAGCCTGCTTGGAAAGATCGTCATAAACGATCAAAGCGTGCTGTTTGTTGTCGCGGAAATATTCACCCATAGAGCAGGCTGAATACGGCACCAGATACTGAAGCGGAGCCGGTTCAGAAGCCGTAGCAGCTACGACGATTGAGTACTCCATGGCACCCATTTCTTCGAGCTGACGAACAATCTGAGCAACGGTCGAGCGTTTCTGCCCAATCGCAACATAGATACAAAACAGCTTCTTGGTATTGTCGCTGCCGCTGTTAACCTGTTTCTGGTTAATAAAGGCGTCAATAGCAATAGCCGTTTTACCGGTCTGACGGTCACCAATAATCAATTCGCGCTGACCACGCCCAACTGGAACCAATGCGTCAAGGGCTTTGATGCCCGTCTGCATGGCTTCGTGAACGGATTTACGCGGGATGATACCTGGAGCCATCTCTTCAGAACGACGCCGTAATTTGGCGTTGATGGGGCCTTTGCCGTCGATCGGATTACCCAGAGCATCAACAACGCGCCCTAACAATTCCGGTCCGACCGGAACGTCAACGATTTGACCGGTTCTGCGAACCGTATCGCCTTCACCCACTTCAAGATCGGAGCCAAAAATCACGACGCCGACGTTATCGGCCTCGAGGTTGAGGGCCATCCCCTGAACACCACTGGAGAAGGTAACCATTTCGCCGGCCTCGACTTTATCGAGACCATATACGCGGGCGATACCATCGCCCACTGAAATCACCCGACCAACTTCGCTGACTTCGGCATCAGCACCAAAGCCTTCGATCTGTTCACGGATGACTTTTGAAATTTCTGCGGCGCGGATTTCCATATTCACCCTTTCATCGCCTGTGCAAGCATATGCAGCTTGCTCCGAATCGATCCGTCAATCTGACGTGAACCAAGACGAACAATCATCCCGCCAAGAATGGAAGGATCAACCGTTGCGTTGATTTGCACATCAGCCTTAAGCTGTTCTTTAAGCCGAGCCGTCAGCGTCGACTTTTGTTCGTCAGATAAAGGATGAGCCGTAATAACATCGGCCACCTTTTCAGAACGAAGGTCAGCTACATATTGGCGATAGGCGCTCGCAATTTCAGGAAAAGCGCCCAGCCGCCCCTTAGCAGCCAACAGATTCAGAAATTTTGCCGTTAAATCATCAATCGCCAGCACAGGAACCAGTGCCGCGATAGCTTTTTCAACATGTTTACGGGAAAAGATTTGATTATTTGCAAGCAGACGAAGTTCTTTTACTTGAGCAAAAGCTTCATCGAATTTGCCGAGACTGGCAGCGACCGTGTCGATCTGCCCTTTTTCCTGTGCAACCTCGAAAAGTGCCAGGGCATAACGGCCACCAAGGCTTGCTTGAATGCTGCCGGATATTTCCATGCGCCTGCCGTCCCCAGATTATAGATGCCTCACCCTGTATTCCGTCCCGGTTCGAAACAACCGGGGCGCACATAGGGCCACACTGGATATGCCGCATAGGCATACAAAACCGGCGAGAATAAAAGATGGAAACCCGAAGGCTTTTCAATCATTTTCACCAGTTATGATCCGCAGTTTAATTAGCAGGGGGGCGGATGGGATGCAAGGTGGCGCTAACCGATTAGCACAAATCGAAAATTCAAAAAAATCGATAAAATAAAGAATAAAAAAACAAAAATGGCAAAAGAGGTTTTAGACCTCTTCTGCCAAAATACTGGCTATTATCAGAGACTTTTCAACAAAACCCCGAAAAACTTCCGATAAAAACAAGAGAGCGCATTTTTTTCTAGGGGAAAGCGCTGTTATTTTGTCTCAGCCTTGAAAAGCGTAATTATCACCCTTGTTGATCAACCCAGACACCGAGTCTTTCTGCTATCTTAGAAAAGGCCGCAGCCGCGCCTTCTGCCGAGTCTTTCAGACAGTCTCCGAGATGGCCGGAATCAGCGGCCAAACGGATATTCAGACCTAATGGAATATATCCCCAAAAATCGATTCCCATATCTGCCGCCGCTAATTCAGCGCCTCCGGCACCAAAAGGATCGGATATTTCGCCACAATGAGGGCATTGATAACCGGCCATATTTTCAATCAGGCCAATAATTGGGGTTTCAGTTTTTCGGAACAGATCGACCGCTCTTTTAGCGTCAATCAATGCCATATCTTGAGGGGTCGAGATAATCAGAACGCCATCCGGCTTATGTTCTCTCACCATGGAAAGCTGAATATCACCGGTTCCAGGGGGCAAATCCACGATCAAAACATCACATTCACTCCAGTCCGCCGCCATTAACTGATTAAATGCGCCTGCAATTTTAGGACCTCGCCAAGCAATAGCCTGATTAGGATCAGCAATCTGCCCCATAGAAAGCATGGCGATCCCGTCTGCGGTTACAACTGGGCGTAACTGATCACTGACAGCCGCAACAGATTGTTGTTTGGCACCCATGAGTAGTGCCTGTGACGGGCCATAAATATCGGCATCAACCAAGCCAACACGCCGTCCCTTTTGCTTCAACAAGAAAGCCAATGCCGCCGACAAGGTAGACTTTCCGACACCGCCCTTGCCGCTTGCAACCGCGATAATCTTGGGTTTTGGCTTACTTAAAACAAAGGTAAAATATGTCTTGGCAACAGAAGGCTCTGCTTGCAACAAATCGGATATTTGTTTTTCAAGAAGGCTGCGCTGCTCTGCCGTCAGACCATTCGCTCGAATAACAAAACGGGCATTCGACTCTTTTAATTCAGCAGCCATAAGCCGCTTGGACTCAATCAGAGTCTGGCCAGAAACAGGGTCAGACACAGAACGTATTTTATCAAAAAGATAGGCTTCTTCAGAAGCGGCATTGCGGTCTTGGTCTGCCATCAATCAACCTGAAATAAAAACAAAGGGGAATATATCTGGATTCAGCTTGGATAATTCAGAAAATCTTGCCGAAAATATCGCAAACATCATAAATTCAGGCGAATGATATATTCTAAATCCTGCTCTTTTAAAGGGAATAACTGCAATAATCCCAAGATCTTTTTTAATCCTATTGCACTCTGATATAGATGTCTTAAAAATTCAATATTTGGCGATTATCTTAATTACCCTATGGCATCTCTTTAAAGAAGAGGGGATCTCATTTTCTATAATAATTGTAAAATTCTGGGGAAAAGTGACCAATATCCGAAATATCATTCAAAAAAGGTTCAGCTATTATTTTCCTATTCTGACTAGAGCTTTCATAAACATCGCTTATATTAAAACAGCTAATCGGATGCTATATTTAGCTCTATCTTAAGGATGCTATGGCTTAAAATATTAAGTCGTGATCAGCATACCCAACAAAAACGATGATGAATTAACGAAGGAGTGACAGTGACACCCCCGAAAAAAATCAGGAGGTCTGCCAAAGTGCGCTACGCCTATGCCGTTACTGCCGCCTTACTTATCGGCGGCGCCACTGCCACCATGGTCACCCAGCAGCCGGTAGATGCACAGGTCGCCCAAAATGCGCCAGGAACAATCCATGCACCGGTTTCAAAGAATGGAACCATACCCGGCTTTGCAGATCTTGTTGAAAAATTACAGCCAGCCGTTGTCAATATTTCGACAACACAAAGGGTAAAAATCCAAACGCCCGCTAATCCTTTTGCTGGCACCCCTTTCGCAGATCTGTTCGGGGGACTTGGCGGCGGAGACACCGGACGCCCTATAACAAGGGAAGCCCAGTCACTAGGTTCCGGCTTCATCGTATCACCGGATGGTTTTGTTGTGACCAATAACCATGTTATTTCGGCAGGCGATCCAGACAAGCAAGGATCAGGCACGGCCAGCGCTGTTGTCGAATCCATCACAGTTACTTTACCGGATCATGGCGAATATAAAGCCCGTGTTGTCGGGCGAGATTCCGCATCAGATCTGGCTTTGCTCAAAATTGAATCAGCAAAACCCCTTCCCTTCGTCCAATTCGGGGATTCGACCAGAACCCGCGTAGGCGATTGGGTGTTGGCGATCGGTAATCCCTTTGGCTTTGGTGGCTCGGTTACCGCTGGCATCGTGTCCGCTATGCATCGTGGCGTTGGTTCAGGGCCTTATAACCGTTACATCCAGACGGATGCGGCCATCAATCAGGGCAACTCCGGCGGGCCAATGTTTGATGTAAACGGGAATGTTATTGGTATTAACACGGCCATTTGGGCGCCAAGTGGTGGCAATATCGGTATTGGTTTCGCGATTCCGGCAGAAATCGCCAAACCTGTGATTGATACATTGCGGTCTGGCAAGAAAGTCCGTCATGGTTATCTGGGCATTGCCATACAGGTGCTGACAGATGACATCGCAGCCGGTCTAGGCTTACCCAAAGATCACGGTGAAATCGTGGTTCGGGTAGAACCCGGCGGCCCCGGATTTAAAGCCGGTATTCGTCAGGGTGATGTTCTGGTTAAGGTCAATAATATTGACGTTACACCAGATAATACCCTCAGCTATCTGGTGGCTAGCCAGCCCGTCGGTGCGAAAGTTCCGATTGAAGTTATCCGTAATGGCAAACATATGACGCTTTCTGCGGTTCTGGCAGAACGCCCGCCAGAAGATCAACTGGCTTCAAATGGTGTGCCAAATAACGATGATAGCGACGATGACAGCAACCAGAACACTCCTCGCAATTCAGCACGGACGGCACTGGGTATCACCTTAGAGCCTGTCACGCCTGAAGTAGCGAACCGGTTAAACATTCCGCAGAATTCGCATGGCCTCTGGATATCGAATGTCGATCAATCCAGCGATGCCGCAGAAAAAGGTCTGCGCCGTGGCGATGTCATTCTGTCCATGAATGAACATCCGGTAACCAGTATCGGGGATGCGGTCGCCGCTATCAACGCAACAAAGGCCGCCGGTCGCAATACTGTGCTTATTCTGGTTCAGCGTGGTAATAACCCGCCGCTCTTCACCGGATTGAAGCTGATGTCTCCGACTAAAAACAAATAATATCTTTAATAAAGAGACCCGTTTTTCTCCCAAGAAAGGCGGGTCTTTTTTATCCGATAAGATTTTTTCTATAACGGGAAAAAGGAAACATCATGAGCAATCCTGTTCAAAAATTCTTCAGCCATGTTTTTAAAGGCGATATACAGGGCGCATTACAATTTGTTCATGAAAATGCTGTCTTCGAAGCCCAAGGCCCCAGCGATGTCCCAATCTATGGCCGCTATAACGGCCATGAAGGTGTCATGAGATTTTTATCTATTCTATCGGGATTATTCGATACCGAAGACTTCAAATGCTTCGAATGGTCAGACTCTGAAAATTATGTTTTTGGCTATGGCTACATGCAGCATAGAGTCAAAAAGACAGGTAAATTATTCAAATCTGAATGGGCGCTTGTGTGCAAAATAGAAAATAATCTTATTATCTCCTACAAAATCTTCGAAGATACCGCCGCTTTGCAATCAGCTTATAAAGACTAAACGCACTTCAAATTCAAAGCCCGATATAACTTTGAGAAGACAGCGACCGAATAAAAAGCCTAACAACTAAGGATACTCTTATCCTCTAGGGGTATCGATAAATAAAAATATCGAGCAAACAGGCTCAGGACAGCTGCACGACTAAGCTAGGCCGTTTAGGCCAGACTTTATTAAAAATTTTAAGGATTAGAATAAGAGGAAAATTGGCCTAATCATTTACCATAAGGAAGGGTAAATGATGGTGGACAGGAATGGATTCGAACCATTGTAGGGCGAAGCCCGGCAGATTTACAGTCTGCTGCCTTTAACCACTCGGCCACCTGTCCACAAGGAGGCGATTTATTTGAGGGGGTTGAATGGAGAAAATATCACCATCTGTCAAGCTGATATTTGAAAAATAATTATTTTTTATTCATTTATCTGAAAAAAAGCGCCCAAAATCACGATAGTCTATTTTACATCCTGTAAGCTGAAACGATATGACGGCTTTCAAATAGGCATTTATCTCGAAAGTGATAATATCGCCTAAGATAACCCAAGACTTGCATTAAGGAATAAATCTATGGCTCGAAGCCGGAATAAGGCCTCCCCCTCTCATCCTCGTTTTTGGGGACGCCATGCGGTTGAAGCGGCTCTCAACAATCCAGAACGCCATATCCGCCGGATATGGGCTACAAGGGAAGCTTTGGCACCCTATGACATTGATAAATCTATTCCGGTTACCTTTTCTGATGTTACCGATCTGGGTCGTTTTGTTCCTAATGATGCCCCGCATCAAGGCATTGTTATCGAGGTTGATCCTCTTCCTGATATCTGGCTGGCTGACCTTTTGGATTTACCAGAAACAGATAAACGCCCGCTTCTAGTTCTCGATCAAGTGACAGATCCCCATAATGTCGGGGCTATTCTACGCTCGGCAGCAGCCTTTGATGCCCTCGGCATCATTACACAAGATCGCCATGCACCTCCAGAATCCGGCGCTTTAGCACGGGCAGCCAGTGGTGCTTTGGAAGTCGTTCCTTGGGTCAGAGTGACTAATCTGGCGCGGGCTTTAGATGAAATTGCAGAAGCCGGTTATTGGCGTATTGGTTTGACGGGTCATTCAGAAGCCACCTTATCCCAAACCTTAGGCAGCGGAAAAACCGCGTTGGTCTTAGGAGCAGAAGGCGAAGGCTTGCGGCAGAATACTGAAGCGCATTGTGATGAATTGGCAAAATTGCCGATCAGCTCTAAAATCGAGAGCCTGAACGTTTCGAATGCGGCGGCTGTCGCCCTTTATGCGGCAGCTGAAAAGCTCAACAGCCAAGACTAATCACAAGGGCAGCATTCTTTCCAAAAGGAGGCTGCCTTTCCATTTCTTTAAAATTACACTCAAAAACAAAAAAGCCGCCGAATGACACGGCGGCTTTCATCAAAATATCAAAAACACTAATTCGGTAGAGGCTGTTGCACCTTTTCAACCCATTCGGGAATAAAGCAAGGCGGACGGTTCGACCATCCGGGTGCCGTCACGGCAGCCTCACTAATCGACTGCAAAAGCGCACGACGCTTTTCAGGATGAAGATGAGGCAAAGCAGCCGATGCACAAAACGCTGATGGTAACCAAGGACGCACAGCCGCTCCAATCAGTCTTTCGTAAAGAAAACGATAGGCTGAAAAACTGTTCAAGCGATCCTGCCCCAAATCAAAAGCCGACATGATAATCAGCGGCGTCATGAAATGCTGCAAAGATTCCAAACCATTGTCATCTGGCAAGTGATGACGAACCGTATCCAAATGATGATACACTTGAGTCTGCGCCCGAATACTGGCCGCTTCGATAACATCCCGCGACCACCGTTCTAAAACCTCATGGCGTTTCAGACCAATATCCAATGAACGACGAATATAGCGTTGAGTTGCAGCCGGAAAGGTCGCAAACTCTTTCATTTCGACCAGAGCCATGGCACCATTAGCTGGTTTCTTCGGGGAATTCATGATACGTCCTCCCTCCCGTTGGTGCTGAAGCGTTTTTCTCTCCGAAACAAGTCGGCAAGAATGTAACGGCAATCTTTTGCTATCTTCACCCCAATTAAGATAATCAAAGGCCGATAACTGACTTAATTGTCCTGTTACCTTTTATAAGAGTGGACATTTTTTCGGCATTAAACAAGCTGTGATTAAAGATAATTTATATAATTAAGGTAAACTCCAAAATTAATTTCAGGAATTCACCCGATCATAAGGGGTGACTAACCAATGCCCCCTATAATTCTGGCTGATCGCTTTTATATGATAGCATTGCTCTAGCCGATCTTGGGTCAAAACTGTTTCGGGTTTACCGTCAGCAACAATTTCACCCCGATGCCATAAAAGAAGCCGATTACAATAACGCGCTGCCAAGGTCAAATCATGCAGGGCAACAACAACAATCCGTCCCTTTTGGGCTTCTTGTGATAACACTTCCATAATTTGCATGGCATAACCCGGATCAAGGGCAGCCAAAGGCTCATCTGCTAATAAAATAGGCGCATCAACTGCCAAAGCCCGCGCTAACAAAATACGAGCCTGCTCACCGCCGGAAAGTGAATCCATAGAACGATCAAGTAAATCGCCCGTTTTTGTTGTTTCAACAGCATGGGCGATGGCATGGCTATCTTGCTGATTTAATCGGTTTAACGATCGCCCATAGCGTAAACGACCAAGCGCAATCAGATCACATGCTTTCACAGGCCATTGGATCCGGCGATCTTGGGGCAAATAGGCAATCGCCTCTGCTTTTTGCTGCGGGGACAAATCAGCAAGGCGACGGTCATTTAAAATGACCTGCCCTCTTTCTGGAGATTGCAAGCCAGCCAATATTTTTAAAAAAGTGGTTTTACCTGCGCCATTGGCTCCAATCATCCCCGTCAGAATACCCCCTTGAAAGGAACAACTGCCACGGAGGGTGATGGCAGCCTGATGGCTACCCGTTTTAAACAGAATATTTCCGGCAGCCAGATGTATCATAGGCTTTTCATCGCCCCCACGCCTTTTATGGCCTGCCGGAAAAAAATAGGTACTCCGATAAAAGCGGTCACGACCCCCAGTTGCAATTCATTCTGTGTCGGTAACAGACGAACAAGGATATCAGCCAAGGTCACTAATAAAGCGCCCCCAATAGCAGAAGGCCATAACAATTCAGAAGGCAACTGACGCGTAAAGGGACGGAGAATATGCGGCACAATCAAGCCGACAAAACCGATTGCACCACTGACCGCAACAGCGCCCCCGACCCCTATCGCCAAAGCGGCCATAATCAACCAACGTAATCGAGCAAGATCAAATCCCAAACTGGCAGCAACGTCATCCCCTAAGATCAACGCATCAAGGGCGGGTGCCGTGCGCCTAAACAGAAATAAAGACAGAAAAAACGGCGCAATAAGGAGCCAGACATGGTTCCAGCTTCGATCTGTAATAGCCCCCATCAACCATGTCATAATTTCCATAGCAGCAAAGGGATTGGGGGATAAATTCAAAGCAAGACTAATACAGGCTCCCGAAAAAGCCGCGATCGCCACGCCCCCTAGGATAAGGCTTTGTGGGTCATTGTGGCGACGGACAAACCATAATAAAGGCAATAACCCAGCCAAAGCACCGATAAAGGCAAAAAGAGGTAAACAAATAGGAAAGCGGGCAGAAAACCCAAAATAGAAAGCTAAAACAGCCCCCAAAGCGGCGGCATTAGAGGTGCCTAATAAAGAAGGGTCAGCCAAAGGATTCCGCAAATACCCCTGATTAACCGCGCCCGCCATTCCCAAAATAGCGCCTACAGCTAAACCAACACAAAGGCGGGGTAAACGTAATAATCCTAAAATCAATCGTGATGTTGGATCACCAACTCCGGTCACCGCCTGCCATAAAGCCATAACACCGATATGGGTTGACCCTATTGATAAAGACAACAGAGCCATCGGCGGCAAACAAATCGACAAATTTATCAGCAGCCGATGCGCTTTATAAAAAGAAGATAGACCAGAGAAAAAACGCATCCGGTCAAGCCTCTTCCTCATCTATTTCCATCATGGGTTCAGTTAAATCGGGCATTTTCTGGCGTTTAAACAGCATCCGGTCTTCAGCGGAAAAGCCTAAATACCAGATAATAGAAGAATAGCTGACCAAGATCATAATAACGCCCAAAGATAGTTCCAGCCATTCAGGGAATTGCCGCGCTACCATTCCCACAGCCCCTGCCCCAATCACCGCCGGAAGCAAGGCCCATTTCCAAGGAGAAACGGGCGCTTTCAAAAGGCGGCGTAACAAGCATGATTTCAAAATGGAGCCAGTGCCAAGCGATATTGCCAAGGCAAGCGCTGGACCCGCGGCAGCCGCCAAATCTGACGGCAAAGGATTATGTCCTAGATGCTTATGCAAAACAGAAATTAACGGAATTGAAAGGGCAGCCTGCAAAGACAGCATCGCAATCGAAATAGCCATATTGGTTTTGGGGGCAATATAAATCAGGGCAGCTTCGGAAATTACGGCTGTTGCCGCCACCACTTCGGCCACCAACAAAAAGCATAATGCCCCGTCACCACCAGCAAAACGAGGGCCAACCAACCCCATGACACCATGACTGGTCAAACCCAAAGCAAGGGTAACACCGGTCTGCGCTGCAATAATCCAAAATCCGACCTGACGCACCTGATTGGCAACCGCCGCTTTATCACCAGCCTCCAGACTACGGGTAATCACAGGGCCCAAAATCGGATCGAAACTGGTTTTCAGCTTTTGCACCAAAGAGGCAACCTGTTGGGCAACATAATAGATCCCAACGACTGAAGAAGAGAAAAATATCCCCAATAAAACGATATCAAGCCGCCTCGAACTCCATTCAATCGCATCAGCAGCGGCCAAGGGAATATTGCGCCTTGCCAGAGAAAATAAGGTCGGAATATGAGGACGCCAACCATGTGGCCAACCGAAACGCTTTAACAGAGGATAAAGCGATGCGGCCAAAGCCGCGACTGCCGAGGCAACATAGGATAATAACAAACCTTCATGCGGCGCTATCCAGATAAAAATCACCGATGAAATAGACAACACCCAAGGCTCGATAATCGCCTGAGCTTTCACGCTAGCTGCAATATCGCCATAAAAAGCCAAGGCCGCCAAGGCGATATCAGCCCAGACTAAAGGCACCACGACCCAAGGAAACAACCAATGGTCAGCAAAGCTGACGGGCGCACCCCGAAACATTAGGATAGGTAGGAAAGACAAAATCACCGCCCCAATCGAAGCGGTTATCAAGGATAGCAATAACGCATCCCCGACGACGTGATTTTCGTCTTTTTTTGTGCGCGCCAATTTCTCGGCTAGCCCTCGGGTCAACCCTAATGTTGCCAGTTGGGCAGTAAATTCTGTTACCAAAATCGCATAGGCAAAACGGCCAAGTGCATCGGCACCATAGATACGCCCCGCAATAAAAAGGAAGGGGATACGGGCTGCCAAGCGTAACAAAAAGCCAAAAACATTGGTGCGCCCACCCTTTGCCAAGATAGCAATGTCTTTGGCTTCAGCTTCTTCTTTATTCAGGGTTGTCAATGTGCGGCACCCCAACTTATCCCCGTGCCGATTTCTACTTCCAGATCAACCGACAACTGAACAATCGGTAAAGCCGCCTCCATCATCACCTGACGAATAACAGGTTTCGCTTTTTCAATATCTTCTTCGGGGACTTCAAAAATCAGTTCATCATGAACCTGTAAAAGCATTTTTACCGAAGAAAGTCCGGCTTTTGCTAAGGTAGGCTCCATTCGCACCATGGCTCGCTTGATAATATCGGCAGACATGCCTTGAATAGGCGCATTGATCGCCTGTCTTTCAGCGGCTTGTCTTTCTGTCACTTTACGGCTTTTTATCGCAGGCAAATGGGTCTTACGACCAAAAGGCGTTTCAACATAGCCATGCAAACGGACAAAATCCAATGTCCGATCAATATAGTGACGAATAGCAGGAAAGCGCTCAAAATAGCGGTCTATCATTTCCTGCGCTGAAAAACGGTCTATTTCCAGTCGCGCTGCCAGACCCCAAGCCGAAATACCATAGAGAATAGCAAAATTGATGGTCTTGGCACGCGCTCGACTTTCACGATCGACATGACCAAATAACTGTTTGGCTGTCAAAGCGTGAATATCTTCTTTCTCCCGAAAAGCTTGTAATAAGGCTTTTTCGTCGGCTACATGCGCCGCCAATCTCAACTCTATCTGTGAATAGTCAGCCGATAATAACAGATGCCCTTTTTTTGCGATAAAGGCATTTCTGATTTCCCGACCAATTTCGGTGCGGATAGGGATATTCTGCAAATTCGGATCAGTAGAAGATAATCGGCCAGTCTGCGCCCCAACCAGACTAAAGCTGGTATGGACACGCCCCGTTTCAGGATTGACCTTGCCAATCAAGGCATCACTATAGGTGCTTTTCAGCTTTGAAAGCTGCCGCCATTCCAAAATCTTGGAGGCAATCACCTCACCTTCGGCCGCTAATCGTTCTAATTCCGTGACATTAGTAGAATATTGTCCGCTTTTGCTCTTTTTACCACCAGCAAGCCCCATCGTCCCGAACAACACTTCACCCAACTGCTTTGGGCTAGAAATCAAGAAACGGCAGCCTGCCAAGACATAGATTTCTTCTTCGAGACGGCTGATATCATGCGCAAAACGGAAAGAGAGATGACGTAAGGCCGCACTATCAACCGTAATACCGGCCTGCTCCATACGGGCAATCACCGGCGGCAAAGGACGATCAACCTCTTCGTAAATACGGGTTGCGCCCTCTGATGACAAACGCGGTTTTAATATTTCCCATAACCGGAAGGTGACATCTGCATCTTCGGCAGCATAACGTGTTGCCGCTGGAATAGGGACATGGTTAAAGGTTATCGCCGATTTGCCGGTGCCACATACGGATTTAAAACTGATGGGCTGGTGGTCAAAATACAAAAGACTCAATTCATCCATACCATGGCCATGGCGACCCGCATCAAGATCATAGCTCAAAAGCATGGTATCATCGAAGGGCTGAACCGAAATTCCATATCGGGACAGAACAATCATATCATATTTGATATTCTGACCGATTTTCAGAATAGAGGGATCTTCCAAAACTGGCTTTAACTTTTTGACAAGAAGCGATAAATCCATTTGATCGGGCTTCTGGTCAAGAAGATCATGGCCTCCATGCCCACAAGGGATATAACAGGCTTTCCCTGCCTCCGTGGACAAACTAACACCGACTAATCGCGCTTGGGTGGCATCCAGATTGTCGGTTTCGGTATCTACCGCGACCTGACCTTTTTGATAGATATCCGCTATCCAGCGATCCAAAGCTTTTTCATCAATCACGGTTTCATAGGCATCAGGGTCGAAACGCTGCGAAGAAGAAGCGGCCATCTCTTTACTACCATCAGCAACAGGTGCGCTCTGCCCTCCCCCAGCTCTCGCCAATAAAGAAGAAAAGCCCTGCTCGCTCAAGAAATCCCGCAAAGGAGTCATATCAACCCCCTTCACCACCAGATTATCCAGTGGTTCGGGTAAAGGCTTATCATCAACCAAAGCTACCAATTCACGGGATAAAATAGCCGTTTCTTTATATTCGATTAGATTTTGTCTTAATTTTGGCTGCTTGATCTCCGGCGCTGATTCCAAAATCTCGCTCAGATTACCATATTCATTGATAAGGCGGCTGGCAGTCTTCGGGCCCACACCGGGAACCCCAGGTATATTATCGGCGGTATCCCCCATCAAGGCGAGAAGATCGCCCAATTTTTCAGGCACAACACCAAATTTTTTAACAACTTGTTCCGAACCGATCAGGCAATTGTTCACCGGATCAAAAAGATTTAATCGCGGCTGAATCAACTGCATCAAATCTTTATCCGAAGAATAGACCGTCACCTGAAATCCGCGTTCTAAGGCAACTCGTGAATAACAGGCGATAATATCATCGGCTTCCAAACCTTCCTGCTCGATAGAAGGCACAGAAAAGGCGCGGGTCGCTTCTCTGATAAGCGGGAATTGCGGCACCAAATCTTCCGGCGGCGGCGGCCGATGGGCTTTATAGGCCGGATATAAATCCTGTCTAAAACTTTTGCGGCTTGAATCAAAAATAACCGCAAAATGGGTCGGGGCATCATCCTGCTTGCGGATATTTTCCACCAGCTTCCAAAGCATGGTGGTAAAACCATAAACCGCTCCCGCAGGCAGTCCAGCCTTGTTCGTTAACGGGGGGAGACGATGATAGGCACGAAAAATATAACCCGATCCATCGATCAGAATAAGATGGGGCTTATCAGAATATTCTGTCACAAAAGACCTTAATAATTAACCGCGATAAATTCGGAATGGATTCCATGTTTGACTGACTGGCATCAGCTCAATCGAATTCATATTAACATGGGCAGGCTGACTAGCGACCCAGAACAGGGTCTCGGCGATATCCTCCGGCTGTAGAGCTTTTGCCCCCTTATAGGTTTCATCATAGGCTTTCTGATCACCTTTGGTTCGTACCAAAGTAAACTCACTCTCGCAAAGACCGGGTTCAATAGACGTTACACGAACACCGGTTCCATGCAAATCACAGCGTAAACCATAAGAAAATTGACGGACAAAGGCTTTTGTCCCACCATAGCAATTCCCGCCGGGATAAGGCCAATGGGCAGCAACCGAACTCAAATTGATAATCATACCCTGACGTTCGATCAGCTTAGGCAATAAATGCTGGGTAATAACGGCCAAGGCAGTGACATTGGTATCGATCATGACACGCCAATCATCCAATTGAATATCAGGCGCAGGCTTGGTGCCAAGGGCAAGACCAGCATTATTGATTAACAAATCAATTTCAGAAAATTCGGAAGGCAGAGAAGCCATCGCTTCCTTCATGGCGCTTTCATCTCTGATATCAAAAACCGTCGGAAAAAGGTTTTCTTCACCCAGCTCACGAACCAATTCGTCTAAACGGTCACGCCTGCGCCCTGTCGCCACCACTTTCCAGCCATGACGCACAAAAAGCCGTGCTGTCGCTGCGCCGAAACCTGCCGTTGCTCCTGTAATTAAAGCGGTCTTGGACATATAATGCTCCTTACTTCCAAAGCGCAGATTCCGACAAAATGATGGCTCAAAATAACCACGCCCTATCCCTCTCAGCGCTGAGCTGAGAATATTCAAAACACAAGGCCAAGGATTTCTCTAAAAACAGAGTCCAGCTTTGTCCATTGCCTGATAGGCCATCAAAACTTCTGCCTTTGCTCTATTGAAAAGCGTTATTACAGATTTCAGCGAATATCCATAACAGGCGATTCCAAAACAGAATTTATTCATCATGCTGACTTTATGGTTACAAAAACGACGCAATATTATACAAAATAGAAAGATAGCCTTCGGCTTCCTGCCGATAATCCCAATCCTGCGTTGACAAGCCCTGCTGTAACCGCCAATCGACAATAGATAATGAATAACGACAGACGCTTTGGCCTTAAACGGCATATTACTTTACCGGGGGAACTGGCTCTTGATGGGGGCAGCCTACTCACCGGAATTGAAATTGCTTATGAAACCTATGGCCACCTCAATGCAGATGCTTCCAATGCGATCCTTATCTGCCACCCGTTAACGGCTGACCAATTTGCGGCATCCGACCACCCGATTACCGGCAAACCGGGCTGGTGGTCGCGGATGATTGGCAAAGGCAAACCCATCGACCCCGAACGCTATTGCATTATTTGTTCCAATGTTCTCGGCTCTTGTCTGGGATCAACGGGGCCTTCCAGCTTTACGCCCGGAACAGCAACCCCTTATGCGATGAATTTTCCGGTGATTACTATTCGGGATATGGTGCGGGCGCAGGCTAAATTACTCGATTATCTCGGCATCCGGCAATTAAAGGCCGTGATCGGCGGTTCAATGGGCGGAATGCAAGCTTTGGAATGGGCATCAACCTATCCCGATCGGGTAAAATCAGTCGTTATTATTGCGTCAACAGCTCGTCACTCAGCACAGAATATCGCTTTTCATGAAGTCGGTCGGCAAGCTATCATGGCGGATCCGAAATGGCGCCAAGGGAACTATTATGAAGAAAAAGACCCACCGGTTGCCGGTCTAGCGGTTGCCCGTATGGCGGCACATATTACCTATTTGTCCGAATCTGGTCTTACCGCCCGTTTCGGACGGCGCTTACAATCGCGACAGGAAAAGAGCTTCGGTTTTGATGCCGATTTTCAGATTGAAAGCTATCTTAGACATCAAGGCATCCGCTTTGTTGAACGCTTTGATGCCAATTCCTATCTCTACATCACTCGAGCAACCGACTATTTCGATCTTGCAGAGGAGCATGGCGGGAAATTAGCCAATGCGTTCAGAGGTACCAAAAGCCGCTTTTGCGTCATCAGCTTCGATAGTGATTGGCTATACCCCACCTCAGAATCACGGGTTATTGTCCATGCGCTCAATGCGGCAGGGGCAGCCGTCAGCTTTATGGAACTATCTAACCCGAACGGCCATGACTCTTTCTTGTTGGATGCGCCAGACCTTCACCGAACGGTTCATGGCTTTTTAGAAGGTGACCGCGCATAATGTCTCTGAAAGATCCTCAAATTCTGGAAGACCCTTCGGTAAAGTTGTCTCTGTCAATGCAACCGGAACGGCCTGATTTCGCGATTATCTCCAATCACATCATCCCCGAAAGTCGGGTGCTGGATATTGGCTGCGGCGATGGCGCGCTAATCGCTTCTTTAAAAAAGAGCAAAAATATTGATGCCCGTGGCATCGAAATCAATCCGGCCAATGTCGGCCATGCGGTGGCGCGGGGATTATCGGTTATTCAGGGCGATGCCGACACCGATCTGATCAATTACCCTGATCAGGCTTTTGATTTTGTTATCCTAAGCCAGACATTGCAGACGACACGCGCCCCGCATCAGGTTTTGAACCAGCTTTTACGCATCGGACGCTATGCTTTTGTTTCTTTCCCGAATTTCGCTTATTGGAAAGTGCGCATGGCTTTAATGCTACGGGGACGGATGCCAGTAACCCCCAATCTGCCTATTTCATGGTATGAAACGGATAACATTCATATGCTGACTATTGAAGATTTCTATGACTTCACGGCACAGCATCGCTACCAAGTAAAAGAAAGCTGGTTTTTCTCTCATAACAGGCAGATTTCTGCGACCGCAGCCAATTGGCGTGCAGAAAGCGCTCTTTTTCTGTTACATCGCTAACGGCAAGGCTATCCTTTTAGGGGTATAGCCTTTTGCTGCCGAATATTACCGCTTCCCATTTTGGAAATCTTCCAACGGCTCATATCCGCGTCCGGCTTTACTTCAATGTCACCAGAGCCCATCAAAGATAGATTAACAGTCTGCGACTGGAATTTGCTAACATCCATCTTGCCAGATCCCATAAGACGAAATGTAGCAGATTGTGAATCTCCGGCAAAAGTAATCTGACCAGAATCCATAATGTCAGATACGACTTTGTCAGCATGAATATCTGAAAAAGAGATCGCGCCAGACCCGTTTAAAATAGCCGTCAAATTATCACGAATAGCACTGGAAACATTTATTTTCCCCGAACCATTTAAAATAACGGTCAAAGGATTTCTGACTTCGCCCTCGATCGAGACAAAGCCAGCGCCAGAAGAAACACATTCTTTCAAAACAGGCAGTGTAATCCGAATTTTGACAGGTGATTTGTGAAAATCGAGATAGTTTAGCCAATTTTTCTTATATAGAATATTCAAGCTATTATTTTTGAACTCGATATCCAAAGACTTCACAGCCTTTGGCGCGACTTGAAGATTAACAGAATAATCATCACCCAGAATGATTTCTGCATCATCAATACCCGCTAAATAAAGCGTGTCGAAAGGTTGAAAATGATAGGATTGGTCAATTCTTCCTGAAAAGGAAGGCCAAACCTTTACCGTTATCACAGCAAAAGCAGCTATAATAAAAAGAAGACAGCATCCTATCTTGTAACGATCACGCACAATCTGCTCTAAAATTATAAAAAAATAATATAATATTTAATTATGTTAATTCATATCATAATTCAACAAGGCTTTTATCTCAATTTTCGCCTTTATAACCATCAATAAAAATCAAATTACGTTTCAGCGCTTTATCTCGATAGACCAAGGCTTTTCCATATTCTGGGGAAGCATACCATGTTTTTGCTGTCGCCATATCTGGAAATTCAATGACCACAATCGCACGGGGCGTCCATTCCCCTTCAATGACATCAATTTCGTTCCCTCGAGATAAATAGCGACCACCATATTGCTTGATAGCGGCAGCCGCTAATTCAATATAGATTTTCCATGCGTCAGGATCTTTAGGATTGGTATCAGAAATAACGTAGGCAGACATAACGCGCCTCTCGGTTTAATATATTCCACTTTTGGAAGAAATTTTAAATAGTGGCAACGACAAAAACACCCCAATTCTTTATAAGATTGGGCTTTATAAATCTATTTTTATCAAATTTTTATAAATTACTTAATATTAAAATAAAAACGGCTTTTACGAAAAAGCCGTTTTTATTTGAAGATCATATTAAGATAAAAGAAAAAGCCTTTTTCAAGGCCTTTATTTTAATCTACCGCTTCTTCTTTAGCTAATTCTTTAACCGCCTGACGATGTTCAGCAGCAGCAGCCTTCAAAACGTCAAAGATTTTATCCAGCGCCTGCGCTTCATCGGTATTTTCCATCGCGCCTAATTCGCGAGCAAGACGGGAAGCTGCCCCTTCAAAAATCTGGCGTTCAGAATAGCTCTGCTCCGGCTGATCGTCGGCACGGAATAAATCACGCACCACTTCAGCAATCGAAACGAGATCACCCGAATTGATCTTGGTTTCATATTCCTGCGCCCGCCGAGACCACATTGTCCGCTTGATACGGGGTTTTCCCTTCAAAGTCTGGATTGCTTCCTGAAGCGTCGCACTGGATGAAAGCTTCCGCATGCCGACTGCTTCTGCTTTGTTTGTCGGAACTCTCAAGGTCATCCGTTCTTTTTCAAAACGCAGGACATAAAGTTCAAGACGGGTTCCGGCAATTTCTTGGCTTTGTAACTCAACTACGCGCCCAACACCGTGCTTGGGATATACGACGTAATCGCCGACGACGAAACTCAACGCCTTGGAAGCCATTATATACGACCTTTCCTGTGGTAAGGTTCCCGTTCGATGACTGATGATCTTAAAAAATCAGGTACCGGACAATTAGATATCATAGCCCGACATCGGTCGGTAGTCATGATGCTGAGAACCCATTTTTGCGATACATTAGGATGAAAAGAGACAACCCATTCACTGATTGTCTAAAATAAAATCCTTGGAAAACCTTCTTTTCGAAAGACTCTTTAACACAAATCAGGCAAAATTCCAACAGGTCATAGCCCAATAACGCCCAAAATTAAGGGACGTTATTAGGCTTATAACAGAAAACGTCGTCTTAAATGGGAAAGGACAAAAAAGGATTAATCACCATTTCCCGGTTTTGGTGAAAAGAACTTTTCCAATTTGCCCGTTACTTCGCGCATTTCATCGGCATCAGCGGGGACATCGGTTTTATGCGTGATATTCGGCCATTCTTCGGCATATTTGCGGTTCAGTTCCATCCAGCTTTCCAGCCCGTTTTCAGTATCAGGCAAAATAGCTTCAGCCGGACATTCTGGTTCGCAAACACCGCAATCAATGCATTCGTTCGGATTGATGACGAGCATATTCTCGCCTTCATAGAAACAATCGACGGGGCAAACCTCGACGCAATCCATATATTTACAACGGATACAGGCATCGGTAACGACATAAGTCATTATAAAAAACTCCGATAAGGGCATCACGTCGCGGCTTTAAAGCTGAATGATGCACCCTGATGAACAACTCAAAGACGCCCGACACGGAAAATCAAAACCATTTTTCCGGCCAAACGCCTACTCTTTCCAGAATACGGAAGCCCTGCTCTAGGAATTAAATGAAATTTTGACAAGTGCCGAAGCATCACAGACAGCCGAGATAACGGAACAGGACGATAAAATTTCACAAATCATTTTTTCAAATGGGCTAAAACAGAAAAAGCATTGGGAATATCAGGCTGTTTTTTAAAAGAAGCGCGCCGACGCTGACTGCCCCGCTTTACGCCCCGCCATACCCATTGCGGCTTATCCTCTTTAATAGAACTATCCTTTTTCTGCTTTTTATCTGCTGGATAAAAACCCAATTTCAACATCAACTTGGCAAAAGCATCAGGTTTCAAACCCATAGCCTGCATCATGCGTTGATCGGGGGCAAAGGAAGGCTGACGCAGCGTGTTATCTTGGCTTTGCGGAATCTTTTCTTTCTTCTTTTGGTCACCCTTTTTAGGCTGTTTCTTTGCTGGTATCGGTAAAGATTCTGCCACTTTTACTTTTCTCGGGGTATCTTTTTTGACCGCTTCCATCGCGGAATCATCCGCCTTCTTTTTTACTCTTTTCGACAGAGGCGAAGCCACCTTTTTTTCTATTTTCTGACCAGAAGAAGGGTGTGACGGATCAATTTTATTATGAGTGGCGTTTTTATCCGTTTTTTGAGAGGGCCGCCGATCATGAACCATCGTTGCCAATTTTTCGGCACTATCGACCCGCAACATCTGACTGCCCAAAGAGCGGAAGCCGACCCATCCAGCCATTTCCGCAGCGTCACTCTCAAGAGGCGTTTCTATCGCTGAACCCCTATTTTTTGGGATAAAAGATAAAAGACGATTATGGAAAACAGCCAATAACGCTAATCGCCAGTCAATTGCTTTCGGCTTTAACAAAGCGGGCATAAAAATATCCAACCGCCCGAAACGAATACCCAAAACCGCCGCCTGTTTTTTCAAAGGGCGGTTCAGCATTTTCAGAATGTCATCGATTTCGACACGGGGAAGACAACCGCCCTTTTCGACCAAAGAAGCCAATAATGCCCGTAAAGAAGGGGGTGTGGTCGATAATTCCGATAACTCTGCCAATTTAACCAGACTACCTAAGGTCTGCTCGATATTACCCTTTAACCATGTAACCAGTCGCTCTTCGATCTGCTTTTGATCGATCGGTGACAAACGATCCAGCTTCCGGCTTAACTTTATCCGAGGCGTTAAAAACGACTTTCCGCGCTCTAAATCGGCAACCGGATATCCGTGCCAGGATATCCCAATTTTTTCTCCTTTTGCTGTCAACAGAGAGAAAGCCTTATCCTCATCTTCTTGCAAGGCTTTAGCGCGCCGCGTCAATTCACCGCCTAAACGACGTTCAGCAGCAGCATGTAACCGTTTCATATCACCATGACGAGCCGCCGGATCAACATGGAAAGAGAAGCCATCCAATCGCCCAATGGATTCTCCTCCCACCAGAACTACGCCATCTTCTGAAAATTCTGTTGGCAGCATATCTAAAGCCGCCTTCCCCATATCCTGCATCAGGATAGAGGTGCGACGATCCACAAAACGCTGGGTTAATCTTTCATGCAAAGCATCCGATAATTTTTCTTCTAATGCCCGCGTTCTTTCAGCCCATTTCGCCGGATTTTCTAACCAATCCGATCGGTGGGCGATATAGGCCCAAATACGAATACCCGCTAAACGCTCGGATAAAGTCGGGACATCACCTTGGACATTATCCAATTTGACGATTTCATCCGCAAACCAACTGACCGGCAAATAGCCATTGCCTTCGGTCAAATAACCAAAAATCCGCCGAACCAAACGACTATGGGCTTCGATGCCGGTCTTTCTAAAATCAGGTAAGCCACAGACCGCCCATAACCTTTTTACAGCCAAAGAAGACCGCGTCCGATCTTTAATGACCGGATCTTCTGCCAATTTATGGAGAACAGCCAAATCATAGCTTTCAGGTGCAGCCCGCAATAAAGGCAGCCCGGGTTTTCGTTCCAAAGAGGCAATCAACGCATCCAAACGGCTGACATCCGGCTGCCCTTCCCGCCAATAGAGATATTCTGCAGGGGAAAAATGATGCTCTTCGATCGCCAAGACTTCTTCTTCGCGAAATTCCAGCGTTTCACCCGGCCATTGCAACACCCCGAAACTGCCATCACGCTGATACCGTCCGGCACGGCCAGCAATCTGTGCCATTTCAGGAATGGTTAGCCTTCTGACTTGCCTTCCATCAAATTTAGTCAAAGAGGCAAAGGCTACATGGGTCACATCCATATTCAACCCCATGCCAATTGCATCAGTCGCCACCAGATAATTGACTTCCCCCGCCTGAAACATCTCGACTTGGGCATTTCTGGTGCGAGGCGACAACGCTCCCATAACGACCGCAGCCCCACCGCGCAGACGACGCAGCATTTCTGCTGTGGCGTAGACCTCTTCAGCTGAAAAGGCGACGACTGCCGAACGTGGAGGCAAACGCGATAATTTGGTCGGGCCACTATAGGACAGGGTCGAAAATCGGGGACGGCTAACAATCTCGATCCCGGGAATTAAACGGCGCAGCAAAGGGCGGAGCGCATCCGACCCTAAAAACATCGTTTCTTCTCGCCCTCTCAAATTCAACAGGCGATCGGTAAAGACATGCCCCCGCTCGCGATCACAGCCTAATTGCACTTCATCCAAAGCCGCAAAGGCAAAATCGCGGTTCATCGGCATAGATTCTGCGGTGCAAAGAAAATATTGGGCTTTCTCCGGCAGAATCTTTTCTTCGCCCGTGATCAAAGCGACACGATCAGCGCCTTTGATCTCGACCACGCGATCATAAACCTCGCGAGCCAGTAACCTTAAAGGAAATCCTATAACACCTGATGTATAGGAACACATCCGTTGAACCGCTAAATGGGTCTTTCCGGTATTGGTCGGGCCCAAAACAGCGATAACAGATGACGAAGAAGAAAGACGGGACATAACGCCTTATAATGTCGGAAGTTATAGGATAAAAGGCAAGCGGTTATCCTTAATCGATTTTCAATATTAAATTTTCTGATCACAAGCTGGCCAAGCCAATATTTTTACCAAAAGCCTTTTCTGTTCATCGCAAATTAAGCTATATCCTATCGCAATTATTGAATTTTCCTCTGTTTTTTCCGTCAAAGAAGTCGAATCTTTACCGGATACAAAGGTTTATCCGGCAAGACTCCTATGGGGCTTAACCGTTTTCAGGACAAATAGACCTAATAAAACGACCTAGTCCCCAAAAAACATTGGCGATTAAGGCCTTCAAGCATCAAGGCCGGATTTAGTATCGAGGTTGTAAACAATGGCAGAAGGTGCCACCCCATCAAATGGATCACCCATTCATCATCACGACAGCAGAGAAAATCTGCCCTTAAAAATGATGGTCGACAGATTGCGGGCATTTACAACGGCACCGGCTATTCCGACCTCTTCGGCTTCCGACTGGCTCCAGCTTAAAACATGGATGCTCCGTGATGATTGGGTCGTTAATCTAGCGGAATCCATTGGTTCCGCTCGTTGGTGGCGCGGCGCTTTTTCTCTAACGGGTTTGATTACCGCTGCATTATTGACCCATCCAGCAAGCCATATCACTTTTCTCCCGCCAGAAAGTGAAGCGGTTGCCCCCATCATCAAATCGAACCCGCAAAAAACACCTTTATCGACAGCGATTGTCGGGATGGATCATTTCTTTCCGGCACCCCCTCAAACAGGTATTATGCCGCCTCAAAGCGAGGCCATGCCTTCACCGACAGCGCCTATCCGTTATCTTAAAAAAGAAAATGGGATAGCACTTAGCCGGATATTCGAGAAAGCCGGACTTTCAACCCAAGAAGCACAAGAAATTGAGAAATTGATCTCAAACAACATCCCCGACAACAATATCGGGGAAGATACCGCTTTTCATTTTATGACCTTGCCACCCACCAGCCCGTTACAAGCGCATCGCCTTAGTCATCTGAATTTTCAGGCTTCTTTTGACAGTATGGTCAATATTGATCGCGAACAAGACGGATTCAAACTAACAAAATACCCGATCCCTTTTACGACCCGCCCTATAAAATTCAGTTTTTCGGTTGAAAAAAACATACGGGAAGATAGCCGAATAGCGGGAATCCCGACATCACTGGCTTCTAAAATAGAAGAATTACTCAAAAAACAGCTTACGAATCCCAGCCTGTTTATCCGTCACCAAACAAGGCTTGATATCGTCTTGAACCAGCGGGAAAATAGCTTGGGTGAGAAAGAAATTGGCGACCCACTCTATATCGCTTTAACGCAAAGCCATACGTCCGACACAAAAAAACCGATAGCACAACTCCGACTTTTCAAATGGGAAAAAGACGGGCAAAGTTACTGGCTGGACGACAAAGGACAGGCACCGCTTGTCAGTGTCAATAATTTCATTCTTCCCGTTGCAGGACGGATAACCTCCTCCTTCGGATATCGCTTTCATCCTATTTTAGGCTTTGGCCGCCTGCATAAAGGTATTGATATCAGCAGCAGCTATGGAACGCCTATCAAAGCGGCTTCAACCGGTCGGGTTATTTTTGCAGGTCGTAAATCAGGCTATGGTAATTTTGCGCTTATTGATCATGGGCAAGGGATTGAAACCTCCTATGCGCATATGAGCTGCCTTCACGTTCATCAAGGACAGAGTGTCTCGCAAGGCCAAGTGATCGGACAAATCGGGACAACTGGCCTTTCAACAGGCCCCCATCTCCATTACGAACTGCATTACAATTCTGTGCCGGTCAATCCTGATCATTTTGTCCAAACGGCACATTATCAGTTAACGGGACAAGACCTAACCGCCTTCAAGAAAAGAACCACAGAAATGCTTGCCTTGGCTGATTCCACTTCCAAACAAAGCTAAAGGTAAAGCGCTACTGCCAAGCATCATTTGCTAGAGTCCCCAGCCCCTCGTCGCGATAAAGTCTTAGTGGAAAGCTATCCTAAAAACCTATCCATTCTTTTTCGGTCGCAACCGCATGAAGGGGCATATCCCAAGCTTCAACCGGAATAGCCTCTGCCTCTTGAATACTCCAAGCTACGCCGATCCGAATGGCATCGGGATAGGCCTTGAAACTGCGATCATAATAGCCTCCGCCTCGTCCCAAACGGCGCAAAGAGCGATCAAAACCGACTAGGGGCGTTAAAATAATATCCGGCACTATTTTTTCAGATTCTGCAACCGGCTGCAAAATACCGCCATTTTTCTCCTCCAAAGGATCATCCGGCCACCAGCGATGAAAATCAAGAGGCGCGTCTTTTTCAACAATTCTCGGCAATAAAGGCGTGATACCGGCATCAATCGCCTGCAAGAAAATAGGCAAAGGGTCGACTTCACCATCATTGGGCAAATAAGCCGAAATAGAGCGTGCTTTTCCGAAATGACTGCGAATATGTTCGGCCAACATCAGCGTAAAAATCAAGCCATCAGCTTTCCAAGAAGGATGATCAGCCAAAGCCTTCCGACGCTGACGAAATAATTTCCGCAGGGATTTTTTATCAGCCATTGACGCTGTTGGCTGAATATTATCCGATGTATCCCCTTCTTTCAGAAGATCAGAAACAGAGAAAAGGGAAGACGACGCAACGGACACAGGCTTCTCCATCCAAGCACAGAAAAATATTCATTATCTTCTTAATTTTGTTGTTATTCTGCTTTTTTCAACCCGTTTTTTCGAAAGAAGGCATAACTATCCCAAAGTTAAAATAAAAACGCGCGTTGTTCTTTCTGCCGCGCCTCTCGAAAGCGGACATATCAAGACCTACAATTTCACCGATCAAACTTGACAGTGAAAAGGCAGCAAGTCATCCCCAACAAATGCTATTGCCGAAACGAGCCGCTGCGCGCCTTCGCCTTTCCTTTTCCCGTCATAAAGTGATTGGAGCTATTGCGCTTCCCGCAATTGTCACCAATATCGCAACCGCTTTGTTTGGTTTGGCTGATATCTGGGCGATAGGCCGCTTGGGCGATCCTCAAGCGCAAGGCGGTGTCGAAATCGGGGCAAAATTATTAACCACCCTCTGTGTGCTTTTTAATTTTTTACGATCTGGAACAACAGCTTTGACGGCTCAAGCCGCCGGAAGACAGAATACAACCCAAGCCAGCCACAGCGCCGCTTTGTCAGAAGCACAATGGCAAGAAGCAGGGTTACGCCACCCCGCGAATATAAAAGCCAGCCATGAAACCGAACAAACGCTTATTCGAGCCGTTTCCCTTGCCTTAGGACTCGGACTTTTATTGATACTTTTCAAAACTTTTATCATTCCCTTCGGGCTATCCTTAATGAATGCCTCTGGCGAGATTAGAGAGCAAGCCGCTTCCTATGTTTGTCTCCGTTACTGGATTGTGCCCCTCATCCTTGCCAATATGGCTTTAAGTGCATGGCTGATCGGGATGCGGTCGATGCGTCTGGTTCTGGCTATCGAGGTTGCCAGTAATTTTTTTCATATTTCAATGGATTGCCTCTTTGTCTTGTTGCTAAAGCAAGGGGTCAATGGGGTCGCCCATGCCTCGATTATCTCTGAAATCTTTTCAACTCTGTTGCTACTGGCGGCTGTCACCCGTTACGCTTCGCCTCAGCTATTATGTCGGCTGGGTTTTCATCGCCTGACATGGCGAAAAGAAACCATCTACAGCTTGTTCAGCCTCAATCGCGATCTGTTCATCCGCACTTTACTGTTAATGACGGCTATTATTTTCTTTACTCGGATGAGTGTCCAGCAAGGCGCTATCTTGCTTGCGGCCAATGCCATTATCAATCAGCTTTTTTCGCTCGCAACACTGATTTTGGATGGCTACGAAAGTTCAGCACAAATATTATGTGGCGAAGCCGCCGGTGCAAAAGATCACAAGCGTTTCTCTCAATTAATGCGCGCTACTTTATTGCAGGCGTTTCTCGTCGCCACTTTATTAGCCCTTATCTACGGATTTTCGGGTTCATTACTGGTCAAATCTTTCACGACGGATTCAATCGTTGCCCAAGCCGCCGGAAATTTATCTATCTGGTTGGTTGTTCTACCCCTTGTTGGAGTCAGCTCCTATGTAATGGATGGCGTTTTTGTTGGTGCTGGATGGAGCAAAGCTATGATGGGTAGTATGGCTATTGCGCTTTTGCTCTTCATGATTAGCCTGTTCTTTTTCAAAGCTTGGGGAAATAATGGCTTATGGTTATCCTTTAGCCTCTTTCTCTTTTATCGCAGTAGTGCCCAACTTATTATTTTGCCATTCATGGAAAAAAGACAATTTTACGCTAATAAAATTTAAAACATTAAAATATATTTTTAAACTATACTCAATTTTTAACAATAAAAATATAAAAATTATTACTTTTTTAAAAATTTTTGTTTTTATGAATAAATATAAAATAAATTTTTACATAAAAACATTAATTTATTTGAAGAAACAGATAAAACCATCCCCATGCAATTAAAATTATCTTATATATTTCACCATTATAGAGCAAATATAAATTAAAATATCTTAAAAAAAACTTTTAAAAATTCTAAAATTCCTCCCATTACTATAAAATTATAGTTAAATTATAAAATTTGGGTGGAGTATGATAAATTTAAGACGGATTATAACCCATTTTTTCTAGCGAGTTGTGTTTTCTACCCACATGCTTTGCACGCAACTGAAATACCGCTCGATATTATCAATGAAGTAGAAGACGGATTTTCTTTTACCCGCTTAGGCATCAATGCCGGTGTTAATAACGGAGACCCGAAAGAATATCTTTTCGATACCGGCTCGGACTCCTTTAATATTGCAGTCGGCATGAATAACAGTGGCACGATGCCCAGCTGGTTTCCACAAACCGGTACCGCCGTATCCAGCCCTTACTGCTATATGTATGGCGATGGCACTTATGGCTATCTACAATCCGATACATCGGTTTCAAATATCCAATTTTATAACAGTACAACAGGCAGCAAAATAGCCAATTATGACACCTCAGCAGGTCTAGGTGTCGCTCTTATTCAAGCCTCTATTGCTACCGAGAACCGATTAAATCCTAACGATATCGGGCAACAGATTTCACCCGATACGGCAGGATTGGATCCTTCACAGGCCTATTATCAAGATTTGTCATGGCAACAATCACTGGACGCTGGGAAAACGCCTGATGAAAATCATTTCTACGGGATTATGGGGGCTGGTGATTTCATTTATAGCGGTGATAATGGCGGCGTTCCCGGCCAACTTACAAAAAGCGGCTATATTGTCGAAGCCAATGGCACCGCAACAACCCCGGGGGATTGCGGAGCAAGCTGTCTTATCGTTGGATTAACACCCGCCTTAAGAGCGCAATTCTTCACCCAAGTGCCTTGGCGCGGCATCATCGGCAGCTTTCCGTTATCGGGAGCCAATGCCGGACGGCAATTTGATGCAATGTTCCAATATGCGCTTGATAACGGACAAAATACCAAAGGGATGCCGACCCTGCTGGATTCCGGAACACCAATGATTATCATCGGCTCAAATGATTTACTGAGTCAGGCGATTGATGCAGGCGCAACAGGCAGCGATGGCTATATCAACGATGTTGACCCCGGTCATATATTAAACATTACCGGCAATGTCCCGAATGGTCAGACAGTTTCGGTTGTCACCGGTGATGGTTCCCAAGGCGATCAAACCAATGTCCTCACATTGGGCAGCAATATCTACACACCCAAGAACTACACCTTGGAAGGCGTTTCTTTCTTCTTACAAAATGCCGTGATGTATGATCTGGAAAATGCTGTAACAGGCTATACGCCTTTTTACGTGTCGGATTATAATTTCACCAATGGGCTAGATGTCTCTTCTGATATGGGAGCATTGGGACTGGCTGGGATCATCTCTGGCAGTAAAGATGTGAATATCCATGATGGCGGTATCGCCTATCTGACCAATAACAACAGCTATACCGGTGCCACCAATATCACTGAAAAACCGAATCGGCGGTTGTTAATTGTCGCGGGAAGTTTCGATATCGCTCATTCCGAAACCGGACAGAGTATCCGCTCTTTATCCGGCAGCGGACAAATCGTCTTAGGCGATAACACCCTGTTGCTTAGTCAGGCACAAGATACCTTCTCCGGTTCTATTCGCGATGATTATGCCGAAGGCTCAACCCGTGCCGCGATGGTGCCGGTGCCTATTTTAATAGGCGGCGAAAACCAGACTCATGGTGGTGTAATCATTGGCGGCGGCCAAGAAATCTTCTCCGGCAATAACAGCTACAGCGAAAAAACCGGCGTTGCAGCGGCTGCCCGACTCATCCTGACAGGAAGATTGGACAAATCACAGGTAGAAAATGCAGGCCGTTTTGAAAATAACGGCGAAACAACAGCCATTGTCAATTCAACCGGCATTGTCAGTGGTAACGGGCTTTTTGCTGGCGGTTTGACTGTCAAGCAAGGGATTGTCACACCGGGCGCCGTGCTCAGCAATGGCGGCGGCACTATGCATGTTTCACACAATTTAGTGTTGGATAGTGCCGCAACCTATCTCACCCAAATAGGCAGCAATAGCGCCAGTATGATTGCTGTAGAGGGCAAGGCAGAAATCAATAACGCCACTCTCGTTAGCTTAGCCACTTCCGAAGCAGGACGACCAAAATTAGGACAAAATTATACGATTTTGACCGCCTCGGACGGCATATCCGGTCAATTTGGAGCCGTCAAAAGTGACCTGACTGGCAATACCCTTTACCCCTTCCTGACAACCGGCGTTGATTACCAGAGCAATATTGTCTCTCTTGAAATCGAACGAAGCCATATCACTTTTACGAATGCCGCCCAAAGCCGAAATGAACGAAATGTTGCAACGGTGCTTGATGCGATGTCCCCAACTTCCAGCTTGGCTCTACCGGCAACACTGCTTGATTTTGCAGCAGTACGGAATGCTTTCAATAGCCTGTCTGGCGAAATTCACGCCTCGGCAAGAACAGCGCTTATTCAAAATGCTACCGAGATCAAGGATATGGCCATCAACCGAATGCGGGCAGCCGACTGTATGCCTGGGGCGTCCACTGAAAAAACCGCCAATCGGGATGGTCGATCTACAGGAGGGACCTGCGACAGCGATCAAGGCCAAACACTTTGGATGCAATCCTACGGCAATTGGAGCCATAACAGCCACAGCGCCAATGCCGCTGGAATGAGCAATTCCGTCGGCGGCTTTGTTCTCGGTGGTGAAACCTCGCTTATCCCGAATTGGCATATCGGTGCCTTGGTTGGCTACGGCCATTCCGGCTTTTCTGTCTCCGAACGGGCTTCATCCGGCCACAGCAATAACGTTACCTTGGGTGGCTATGCCAATACGCATTGGGATCGTCTTGGCTTAAGAATGGGCGCAACCTATACATGGGATAGATTGGCAACCCGCCGAAAAGTGCTTTACGCTGATTTTACCGATCAACAAAGCAGTCGCTATAATGGCGGCACCATGCAGGCCTTTGCGGATATAGGCTATCGCTTTGACATTGGTCGAGTCATGGTCGAACCTTTTGGAAATGCCGCCTATATCAACCAGCATACCAATGCTTTCCGTGAATCAGGCGGCGCAGCGACGCTCTCTGGCCATGCTTTAAGCAGCAATATGGCCTATGCGACTTTCGGTTCCTGCCTGGCTTCCCGTGTAAAACTTGGGAAATCGACTGTCCTGACACCAAATGCTACAATCGGTTATCGCCATGCCTTCGGGACAATCACGCCTTTCATCAAAGAAAATTTTCTTAATCAAACGGCCAACTTCAATGTTTCGGCTGTGCCTTTAGCTGAAAATGCGGCGATGGTCAGCGTCGGCCTACAAGCCCAAGTCAAAAATCGCCTACAGCTAGGCCTTAGCTATAGCGGCCAATATAGCGCGCATTATTCTTCAAGCGGCCTCAAAGGGAACATTTCATGGGTCTTCTGATTCAATCATTTTTCTCCGACCAAACTTCCTCGTAATCTCTTCAAGGCGTTACCTTCAAAAGTAACGCCTTTTTTTTCAAAAAAGAAAATACCCAAACAAAGGACAGGTGGTTCAAAAAGACACATCCTTCACGTCAATGAAGAAATAAGGCCAAAAACTGGCCTTTTTCTGCTGACAACCGATTCAACATATTGACTCACGACTCACTTTAGACTAGCAAAGCACACTTAAATCGGCATGTGTGGGTTAACCACGCATGATCCGATCTGTTTATTTCATGCCTTTGAAGAAGTGATAAAAGCCATGTTCGCTATCGTGCGCACCGGCGGGAAGCAATACCGCGTCGCCGCTGGAGACAAAATTGTTGTCGAAAAAATCGCCGGCGAGGCGGGAACGACAGTTTCGCTTGAAGATGTCCTGCTTGCCGGTGAGGGTGCTGATCTCCAGCCCGTCAAAGGTTTGACGGTTTCAGCCGAGATCATTGCTCAGGCTAAGGCGGAAAAAGTCATCGTCTTCAAGAAACGTCGCCGCCATAACTACCGTCGCCGTAACGGCCACCGTCAGCAGCATACAATCCTCAAGATTGTATCAGTCGGTAACGCCGCTGCTTAATATTGGATTTCATTTTTTCTGAAACTTTTTCCGGCACTATGCGTATTCTACCCAACAGTGCCAGAGTGTTCAGAATTTTAACCGGCAAAGTCGTTACTTTTAAAAGTCGGCTTTTCTAGGGAGATTACATAATGGCACATAAGAAAGCAGGCGGTTCATCGCGTAACGGCCGCGATTCAGCTGGTCGTCGCCTTGGTGTTAAAAAATTTGGTGGTGAAAGCGTTATTGGCGGTAATATTATTATTCGCCAGCGCGGTACCAAAGTTTACGCCGGTCGCAATGTAGGTATGGGCAAAGACCATACTTTATTTGCAACAGCCGAAGGCCGTGTCCTTTTCCATAAAGGAAAACTCGGACGCAGCTATGTCAGCGTCGATGCCTTGCCATTGGCAGCTGAATAACGGATGATCCGTTGGGTCGTCCGTCAAAGGGCGACCCGATTATGACTGTTTTTAAACAGTCACGAAAGGGAGCAGCCTTCTAAAAGGCCGCTCTTTTTTTTTTGATCGGTTAGTCGCTCATATAATTCGTCTTTTGTCATGATACTGTCTTTTAAGGCAGCTACAAACGGGGGGCGATCAAGGAGCTTAAACCGATGTTCGCTTATAGCGCACGTTTATTTTTGAGGCCGCTTTGGTCAGATGACCTCGGCGTTTTACTCGATCTGCTGGACACTGCCTCATCACGCAGCGGATTACTCGACTCTCCCGATAACGATGTAACCCGTTATTTACGGGGTAACGCCGCACGGCTTATTCACGAAAATGACGTTACCCGCCCTCATTCCGGCATTTTTTTGCGGGATGGGAAAGAACCCCGTCTTATCGGCATCACAGCCCTTGCGGGAAAAGAAGCGCATTTCTTCTGCTGGATTGCTCCCGCTTTTCGGAGACAAGGCTTTGCCACCGAAGCCAGCCGACTAATGCTTCATTTCGCGGATGAGGCCTTGCGCCTTCCGTCGCTGACGGCAGCCTATGATCATGCAGATGCTGCGGCTGAAAAATTGCTGACCAAACTTGGTTTTTCTGAAAAACAGAAAACGCCGCCAACGGCTGCTTGGGGTGCTGCCAATACATCGGTATCTTTTTTACCGGAAAATTTTATCAAGGAAGAACGCGTCAGGGTGTTTTCCTCCTGTCAGCCTTCTCTTCAACACAGTAAATCACAGACTATTTCAAACAGAAGCGCGACACTCGCTGCGTAATATGATAACGGGGATATTATTGATGAAATGATATCCCCTGCTATCATCAGGCTTTTAAACAAGCCCTGTTTTCTTTATAGTCTGTCACACCATGCAATTTCTCGATCAGGCAAAAATCTATCTTCGCTCCGGTGCTGGTGGCCCCGGTGCGGTCTCTTTCCGCCATGAAAAATATATTGAATATGGCGGCCCCGATGGGGGTAACGGGGGCAAAGGCGGCGACATTGTTTTTGAAGCCGTCCCCGGCCTCAATACTCTGATCGACTTTCGTTATACCCAGCATTTCCGCGCAGCCCGTGGTGCTAGTGGGGCTGGTTCCAACAAAACCGGCGCAGGTGCCAAAGATTTGGTCATCCATGTTCCAGTAGGCACACAGGTTCTTTCAGAAGATAAAGAAGAAATTCTCCATGACTTCACCAAAGTCGGTGAAAAAGTCATTTTCTTAAAAGGGGGCGACGGTGGTCGCGGTAACGCCAGCTATAAAAGCTCGACCAATCGCGCACCTCGTCAGCACGGCCCCGGTTGGCCAGCCCAAGAAGCATGGGTCTGGCTCAGACTGAAATTACTCGCGGATGTAGGACTGGTTGGCCTACCTAATGCCGGTAAATCCACTTTTCTTAAAGCCACGACTAACGCCCATCCTAAAATTGGGAATTATCCCTTCACGACGCTATTCCCTCAATTGGGGGTTGTGCGCCGCCATGGTCAGGAATTTGTTCTGGCTGATATTCCCGGACTTATTGAGGGGGCTTCCGAAGGTATCGGCATTGGTGACCGATTCTTGGGTCATATCGAACGCTGCCGGATTTTACTGCATCTGATTGATGCCTCCGGCGAAGACCCGATAGCCGCATGGCATGAGGTGCAAAACGAGCTGGCTCTTTATGGGGCTGGTCTCGCCGAAAAACCGCAATTACTGGCGCTGAATAAGATAGACAGCGTTGATGAAGAAACATGTGCTGAGCTTTCGCAGGCATTGGAAGAAGCCAGCGGACAGAAAGTTCTGCTTTTATCCGGTGCCACAGGCCAAGGCTTGGATCCCATCCTTGACCAACTTATTACCATGACCGGTCGCGCTATGGAAAAAGCTCAAGAGAGCAGCGCCCAAACGGAGAAAATATGGTCGCCGATCTAACTTCTGATATTTCAGAATCCCAAGAGCAAGAAACAGAAACTAACTCTGCCAATAATAACGGCGCGGTTTTCCGACCGGAAAACTGCCCGCGACTGGTTATAAAAATTGGTTCTTCTTTGCTCGTTGACCAACGCGGTCAAGTTCGTCGCGATTGGCTGCAAACTGTCGCCTATGACATTGCCAAATTGCATCAAGCTGGACAGCAAATCATTGTTGTTTCCTCAGGCGCTATTGCCCTTGGAGCCAGACGCTTGAACTTGCCACGCGGTGGACGGGCTTCCTTAGAAGATGCTCAAGCCTCGGCTTCTGTCGGACAAATTTTGCTTAGCCAATGCTGGGCAGAATTGCTGGGTGCATGCAGCTTGGATTCATCCCAAATTCTACTGACACTGGATGATCTGGAAGATCGCCGCCGCTATCTGAACGTCTCGGCTACGCTTGATCGCCTGCTTTCTCTTGGTGTCGTGCCAGTCATCAATGAAAATGACTCGATTGCGACCGCAGAAATTCGTTTTGGAGATAATGACCGTCTCGCCGCTCGCATCGGGCAGGCCAGCCATGCCTCTGGCGTTATCCTCTTTTCAGATGTGGATGGCCTTTACACGGCCAACCCAATGAAAGATCCCAACGCCAAACGGATTGATCGGGTCGAACATATCGACAATAGCACAGAAGCTATGGCTAGCAGTGATTCCGCTTCCGGTATGGGTTCTGGCGGCATGGCTTCCAAGGTAGAAGCAGCGCGTATCGCTACCTATTCCGGTGTTAATCTCGCGATTACAACGGGTAAACGCCCTTCCCCGCTGACGATGTTTTTGAATGATGGTGCTGGCACGCTATTCACAGCCGACGAAAGCGCTTCAGCTCATAAAACATGGCTGGCCGGACGATTAACCGCTCATGGTCAGGTTTATATCGATCAAGGTGCGGTCGAGGCACTCCATGATGGGAACAGCCTGCTCCCTGCGGGCGTCTGCTCCATAGAAGGCAAATTCAACCGCGGTGACGTGGTCGATATCCTCGATCAAGAACACAACCTTATTGCACGGGGTCTGATCGAATATGACAGCGAAGATTCTGCCCAAATCACAGGCAAGCGGTCGCAGGAAATTGCTGATATTCTAGGATATGAGGCCAGAACAGCCCTAATCCATCGCAATCATATGGTTATGCTATGAAAATTGCACTGACGGGGGGAACAGGTTTTATTGGCGGCCACGTCTTCGACAATACCGCAGGTCGCGGTATTGGTATCAAGGCTTTGACCCGACGACCACAACCAGCAAGACCGGGGGTAGAGTGGATTCGCGGTAGCCTCGAAGATGAAGACAGCCTCAAAAAACTGGTTTCATCCTGTCAGGCCGTTATTCATATGGCGGGTGCTGTCAAAGCAGAAAACAGGGAAGCCTTCGCGCATATCAATCTGACCGGCACAGAAAAACTTCTCGCTGCCACCAAGGCCGCCGGAATAAAACGCTTTATTCATGTCTCCTCTTTGGCGGCTAGAGAAGCCGAACTCTCTGATTATGGCTGGTCAAAAGCTCAATCAGAAGAAAAGGTAAGATCCTCTGGACTCGACTGGACGATCATCCGACCGCCTGCCGTTTATGGTTCAGGAGATCGGGAAATGCTTGAAATGTTCAGAATGGCGGTTATGGGATTGATGATTATGCCGCCCAAGGGCAGGTTATCCCTGATTGCTGCCGATGACCTTTCGCGCCTTATCCTGACATTGGTCGATCGAGATATCAGCCAGCCAAGCTATCACCAACTTTATGAAGTCGATGACGGCCACCCCGAAGGCTGGAGCCAAAATGAATTCGCCCAAGCCTTGGGACATGCCGTTGGACGCCCATCTATAAAGGTCGTCCATCTTCCTAAAAAATTGCTCTCTTTTGCCTCCAAAGCAGAAGGCTGGCTGCATGGGAATCAGGCACGGCTAACACAAGATCGCGTCCGTTATTTCTGCCATCCTGATTGGGTCATCAATCCGACTTTGAGACCCCCTACCACCCTTTGGGAGCCTCAAATCCCGCTTGAAGAAGGCTTGAACCAAACCGCTATCTGGTATCGCTCCCGTGGTTGGCTCAAAAGATAGCCGTTAGCAAACAGATAAAGATCGTAATTCCTTCAAAGCCATACGGATACTGACCCAAGCCCCCTGCAAAGCTAATAAAGCCATAATAAAGGCAACGGAATAATCAGGCCAGCCTTTCACCCAATGAAACACGCCAAAGGCCGCTAATAAAACAGCACAATTACCGATCACATCATTCCGCGAACAAATCCATGCAGAATGCATATTGGCGTCCTCCGATCTGAACCGCCATAATAATAAAAATGAAACGACATTAACTAACAAGGCAACTGACCCGACAATACCCATGGTCGTCGCTTCTGGGACAATAGCATGCGCTATATGCCAAAGGGTAATGGCCAAGACCCATGCGCCTAACAGTCCCATAGTAGCGCCTTTTAGAACCGCTGCCCAAGCGGTTACCCGCAGCGAATACCCTATAACCAACAAACTAATGGCATAGTTAAGGGCATCCCCTAAAAAATCCAAAGCATCCCCTTGCAAAGAAGCCGATTTTGAAAAAAATCCGGTGGCAATCTCGGCTAAAAACATCATGCTATTAAGAATAAAAACAGCCCATAAGGCCTTTTTATATCCTTCGGGTATAGCCTTCTTTGTTGAAAAATCAGGCTCGCAACAACATTTTTTACCCATCATATCTGCTCGTGTCATGAGGAATCAGGACAGCTAAAATGCAGTCTATAGTTACTATAGGGTCAAGCGATGAATACGGATTATTTCACGATCGGCAAATTAGCCAAAGAGACTGATACCAAAGTCGTTACGATCCGCTATTACGAATCTATTGGACTGCTCCCTGCCCCGCTTCGCACAGGCCATAATTATAGACTTTATAACCGCGACCACTTTAAGAGATTATCTTTCATTCGCCGCTGCCGGTCATTGGGCTTCCCGTTATCTCAAATTCGCGAGATTATCGCATTGACCGACCAACCCGATGAGGATTGTCAAAAGGTCGATAAAATCGCACGCGGCCATTTAGATATCATCGAATCCAAAATTCAGGATTTAACCCAGCTCGCTTCCGAACTCAGGCAAAAAATAATCGCCTGTCAGGGCGGGACAATAGCACAATGCTGTATTCTCAAAAATTTATCAAAGCAGAATACAACGCCCATAAAATCAACCCCATAAAAAAAACGGGTCGGTGATAAAACCGACCCGCTTGAGGATTAAGCGCTTTTTATTGGAATTAGAATTCTGACCAATCATCATCCGCCATAGGCTTAGGGGCCGGATTGGGTTTGGCGGCCGCTTTCGCCGGAGCAGATTTAGCGGTGCTTCTTGAGGCAGGCCGTGCCGCTGACTTCTTCGGAGCTGAAGTTATCGCTGGCGTGCTTGCAAACTGCCGCGTATTGCCCAGCTTAAACATGCTGACCTGTTCCATCATGGCGGTGGTTTCATTGGCCAGATTACGGGCTGCTGCGGTTGATTCTTCAACCATTGCGGCATTCTGCTGGGTCACACCGTCCATTTCAGAAACAGCCGTGTTGACCTGTTTCAAGCCAACAGCCTGCTCTTCCGCCATAGTAGAAGCCTCGGTCACTTTTTGACCCACTTCACGGATTTGGCTGACGATGCGTTCCAGCGCCTGCCCTGCTTCATTCACAAGAACCACGCCGCTATCAACCTCGCCTGCACTAGCCGTGATTTTTTCTTTCACATCCTTAGCCGCTTCAGCCGAACGCTGTGCCAAAGCCCGCACTTCCGAGGCCACAACCGCAAATCCCTTACCAGCATCACCCGCACGAGCGGCTTCAACACCAGCATTCAAAGCCAGCAAGTTGGTCTGGAAAGCAATACCATCAATGACGCTGATGATCTGTGCGATTTCGTTGGAAGAGCTTTCGATTTTGGCCATAGCATCCATGGCTCTATGAACAATATCGCCGCTCTTTTCAGCTTCACCACGAACTTTATCTGTAATCTGTCTGGATTCTTTGGCGCCGACAGCAGCCTGATCGACGGTTCTGGAGATCTCTTCCATAGCAGCCGAAGTTTCTTCAAGGCTGGCAGCTTGCTGTTCTGTCCGCTGAGACAGATCATCAGAAGCCTGACGAATTTCACTCGCCCCATTCTGGATATTTTCAGCCGATTTTATGATCTGCGCCATGGTCTGTTCCAAAAAGCCCATGGAATTATTAAAGTTTTCCTGAATTTCCGAGAAAGAGCCAGACAAATTACCTCTAATCCGCGTTGTCAGATCATAATTACGCAAGCCTTCCAAAGCCTCACCGATACCAGAAAACAAGGAATCTAATTCCATCTGCTTTTGTTTTTCGGCATTTCGCAACTTATCGCGGAAAGTTTTCAAGGCCTCAAGCAAGGTACCGATTTCATCTTCGCTAGGTTCAAGGGCAACCTGAACATCCATATTGCCATCCGCTAACTCAGCTAAAGCATTGGTAATGATTCCCAAAGGCTGGACGACTGCCTTAATCATAATATTAGCTATAAGGAGTGAAAGTAAAATAGCCAATATCGTAATAATTATTGTTACAATGCGAACATAATTATATGAATGCTCCATATCGGCGACTTTGTTGGCATTCGCCTGTTTTTCAACATTCTGTAAAGTGCCAAGCGCTGAAGTCACCTGATCAAAAGCAGGAAGTTCTTTCCAGAAGAAATCGCGGCCTTCATTCATCCGCCCCTGCTGAATTGCATCCAATGTGGCTTTATTTACGCTAACATAATTCTGCCAGTTTGCTAGGCTCAGGACCCATTGATTTTTGTGGGGAATTTTGATTCAGTCTCTGTGAGGAGACTGAAGATGAGCGACCTGTTTTGGCTGACGGACGAACAAATGGGGCGTCTTCGGCCGTTCTTTCCCAAGAGCCACGGCAAACCTCGCGTTGATGACCGCCGAGTGTTGAGCGGGATCATTTTTGTGAACCGCAATGGGATGCGCTGGCGTGATGCGCCCCGGGAATACGGCCCCCACAAGACGCTCTACAACCGTTGGAAGCGTTGGAGCGACATGGGGATCTTTTCCCGGATGATGGACGGTCTGGCTGCCGGAAGGGCAGAGCCCCAGACGATTATGATTGATGCGACCTATCTCAAGGCGCACCGCACGGCTTCGAGCCTGCGGCTAAAAAAGGGGATCCAGGCCGCCTGATCGGTCGCACCAAAGGCGGTATGAATACCAAGCTCCATGCGGTCACCGATCAGAACGGACGACCGCTGAGCTTTTTCATGACGGCAGGGCAGATCAGCGATTATACCGGTGCCGCTGCCCTGCTGGACAGTCTGCCTGCAGCACAATGGATGCTGGGAGATCGAGGTTATGATGCTGACTGGTTCAGAGACGCCCTGGAAGAGAAAGGGATAAAGCCCTGCATTCCAGGACGGAAATCTCGCGGAAAACCAGTCAAATACGACAAGCGAAAATACAAAAGACGCAACCGCATCGAGATCATGTTCGGAAGGCTCAAGGACTGGCGGCGGATCGCAACACGCTATGACAGGTCTCCGACAGTCTTCTTCTCAGCCGTCTGCCTCGCCGCAACCATCATGTTCTGGTTATG

Protein sequences of DBSCAN-SWA_4

>NC_018145|1091000:1153371|1123946_1125494_-|WP_014848909.1|DBSCAN-SWA
MTTLNKEEAEAKDIAILAKGGRTNVFGFLLRLAARIPFLFIAGRIYGADALGRFAYAILVTEFTAQLATLGLTRGLAEKLARTKKDENHVVGDALLLSLITASIGAVILSFLPILMFRGAPVSFADHWLFPWVVVPLVWADIALAALAFYGDIAASVKAQAIIEPWVLSISSVIFIWIAPHEGLLLSYVASAVAALAASLYPLLKRFGWPHGWRPHIPTLFSLARRNIPLAAADAIEWSSRRLDIVLLGIFFSSSVVGIYYVAQQVASLVQKLKTSFDPILGPVITRSLEAGDKAAVANQVRQVGFWIIAAQTGVTLALGLTSHGVMGLVGPRFAGGDGALCFLLVAEVVAATAVISEAALIYIAPKTNMAISIAMLSLQAALSIPLISVLHKHLGHNPLPSDLAAAAGPALALAISLGTGSILKSCLLRRLLKAPVSPWKWALLPAVIGAGAVGMVARQFPEWLELSLGVIMILVSYSSIIWYLGFSAEDRMLFKRQKMPDLTEPMMEIDEEEA
>NC_018145|1091000:1153371|1100055_1100256_-|WP_041572956.1|DBSCAN-SWA
MAVDGNFKTANGSSIGANFKNDNNEKEAGLNYSHLFGNGITLGIHLNKDFEKYNRNKVDTNVKNPF
>NC_018145|1091000:1153371|1116315_1117344_-|WP_014848902.1|DBSCAN-SWA
MADQDRNAASEEAYLFDKIRSVSDPVSGQTLIESKRLMAAELKESNARFVIRANGLTAEQRSLLEKQISDLLQAEPSVAKTYFTFVLSKPKPKIIAVASGKGGVGKSTLSAALAFLLKQKGRRVGLVDADIYGPSQALLMGAKQQSVAAVSDQLRPVVTADGIAMLSMGQIADPNQAIAWRGPKIAGAFNQLMAADWSECDVLIVDLPPGTGDIQLSMVREHKPDGVLIISTPQDMALIDAKRAVDLFRKTETPIIGLIENMAGYQCPHCGEISDPFGAGGAELAAADMGIDFWGYIPLGLNIRLAADSGHLGDCLKDSAEGAAAAFSKIAERLGVWVDQQG
>NC_018145|1091000:1153371|1105971_1106334_+|WP_012817423.1|DBSCAN-SWA
MASRILIVEDNELNLKLFCDLLRAHHFDVEPVRDGRGMIARAHSFMPDLIIMDIQLPHISGLELIGQIRKTKELCHIPIMAVTAYAAPEDEQKIRQAGATGYIAKPISVVRFLEAVKTLI
>NC_018145|1091000:1153371|1133425_1133764_-|WP_011240167.1|DBSCAN-SWA
MTYVVTDACIRCKYMDCVEVCPVDCFYEGENMLVINPNECIDCGVCEPECPAEAILPDTENGLESWMELNRKYAEEWPNITHKTDVPADADEMREVTGKLEKFFSPKPGNGD
>NC_018145|1091000:1153371|1139704_1141150_+|WP_014848919.1|DBSCAN-SWA
MLLPKRAAARLRLSFSRHKVIGAIALPAIVTNIATALFGLADIWAIGRLGDPQAQGGVEIGAKLLTTLCVLFNFLRSGTTALTAQAAGRQNTTQASHSAALSEAQWQEAGLRHPANIKASHETEQTLIRAVSLALGLGLLLILFKTFIIPFGLSLMNASGEIREQAASYVCLRYWIVPLILANMALSAWLIGMRSMRLVLAIEVASNFFHISMDCLFVLLLKQGVNGVAHASIISEIFSTLLLLAAVTRYASPQLLCRLGFHRLTWRKETIYSLFSLNRDLFIRTLLLMTAIIFFTRMSVQQGAILLAANAIINQLFSLATLILDGYESSAQILCGEAAGAKDHKRFSQLMRATLLQAFLVATLLALIYGFSGSLLVKSFTTDSIVAQAAGNLSIWLVVLPLVGVSSYVMDGVFVGAGWSKAMMGSMAIALLLFMISLFFFKAWGNNGLWLSFSLFLFYRSSAQLIILPFMEKRQFYANKI
>NC_018145|1091000:1153371|1115327_1115882_-|WP_014848901.1|DBSCAN-SWA
MEISGSIQASLGGRYALALFEVAQEKGQIDTVAASLGKFDEAFAQVKELRLLANNQIFSRKHVEKAIAALVPVLAIDDLTAKFLNLLAAKGRLGAFPEIASAYRQYVADLRSEKVADVITAHPLSDEQKSTLTARLKEQLKADVQINATVDPSILGGMIVRLGSRQIDGSIRSKLHMLAQAMKG
>NC_018145|1091000:1153371|1096271_1096937_+|WP_014848890.1|DBSCAN-SWA
MGRKRLSDFWSARLACHDLSCLRGDRLLFTHLSFEVKAGEAVLITGANGIGKSSLLRLLAGFLKPFSGHVEKWGRVAFADEALAMDRHLPLEKALAYWAALDGVLGAEKEAMVVMALDRLADSPVRLLSTGQRKRAVLARLLASQAAIWLLDEPANGLDAASVRALIEMIEHHRQKGGIILAVSHQGLDMADYKILSLENFVAESGQSSGLFDLLDESHFS
>NC_018145|1091000:1153371|1152614_1153371_+|WP_141914866.1|transposase|DBSCAN-SWA
MSDLFWLTDEQMGRLRPFFPKSHGKPRVDDRRVLSGIIFVNRNGMRWRDAPREYGPHKTLYNRWKRWSDMGIFSRMMDGLAAGRAEPQTIMIDATYLKAHRTASSLRPKKGDPGRLIGRTKGGMNTKLHAVTDQNGRPLSFFMTAGQISDYTGAAALLDSLPAAQWMLGDRGYDADWFRDALEEKGIKPCIPGRKSRGKPVKYDKRKYKRRNRIEIMFGRLKDWRRIATRYDRSPTVFFSAVCLAATIMFWL
>NC_018145|1091000:1153371|1113795_1115325_-|WP_014848900.1|DBSCAN-SWA
MEIRAAEISKVIREQIEGFGADAEVSEVGRVISVGDGIARVYGLDKVEAGEMVTFSSGVQGMALNLEADNVGVVIFGSDLEVGEGDTVRRTGQIVDVPVGPELLGRVVDALGNPIDGKGPINAKLRRRSEEMAPGIIPRKSVHEAMQTGIKALDALVPVGRGQRELIIGDRQTGKTAIAIDAFINQKQVNSGSDNTKKLFCIYVAIGQKRSTVAQIVRQLEEMGAMEYSIVVAATASEPAPLQYLVPYSACSMGEYFRDNKQHALIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDKMGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFYQGIRPAINVGLSVSRVGSAAQTKAMKKVAGSIKLELAQYREMAAFAQFGSDLDASTQKLLNRGKRLTELLKQPQFHPMPFEEQVVSLFAGTNGYIDGIEVADVNRYEEAMLSYMRSSHNDLLATIRETGDFSDETKSKLTAALDNFAKIFA
>NC_018145|1091000:1153371|1137178_1138750_+|WP_014848917.1|DBSCAN-SWA
MAEGATPSNGSPIHHHDSRENLPLKMMVDRLRAFTTAPAIPTSSASDWLQLKTWMLRDDWVVNLAESIGSARWWRGAFSLTGLITAALLTHPASHITFLPPESEAVAPIIKSNPQKTPLSTAIVGMDHFFPAPPQTGIMPPQSEAMPSPTAPIRYLKKENGIALSRIFEKAGLSTQEAQEIEKLISNNIPDNNIGEDTAFHFMTLPPTSPLQAHRLSHLNFQASFDSMVNIDREQDGFKLTKYPIPFTTRPIKFSFSVEKNIREDSRIAGIPTSLASKIEELLKKQLTNPSLFIRHQTRLDIVLNQRENSLGEKEIGDPLYIALTQSHTSDTKKPIAQLRLFKWEKDGQSYWLDDKGQAPLVSVNNFILPVAGRITSSFGYRFHPILGFGRLHKGIDISSSYGTPIKAASTGRVIFAGRKSGYGNFALIDHGQGIETSYAHMSCLHVHQGQSVSQGQVIGQIGTTGLSTGPHLHYELHYNSVPVNPDHFVQTAHYQLTGQDLTAFKKRTTEMLALADSTSKQS
>NC_018145|1091000:1153371|1091989_1093714_+|WP_014848888.1|DBSCAN-SWA
MVQLPSSARHGNETENQQFLDHLREISDHVLTSEGEMHHYCTGFRFGSGKVLAVVRPTSLVEMWHVVEACVDAGKIIIMQAANTGLTGGSTPDGDDYDRDIVLISGIGITGVKQINKGEQVICLPGATLYDLETILRPLGREPHSVIGSSCIGASVFGGVCNNSGGALMQRGPAFTQLTLYARINEQGKLELVNHLGVRLGDDPETILSRVEKGDYTEDDVINDESKHASDCEYHNHIRDIEAETPARFNADPSRLYESSGSAGKVAVFAVRLDTFPQQKNAKVFYIGTNDPDELTELRRQVLKSFKYLPISGEYMHRHAYDIAAKYGKDTFLAIEYLGTDRLPQLFAMKGWFDGLNNRVSFLPRYLTDRVMQFASTLFPHHLPKRMDDFRDRYEHHLILKVSEEGTEEARGFLKDFFEKASGGYFECSDEEGKKAFLHRFAAAGAAIRYRDVHQDEVEDIVALDIALPRNNKAWEEHLPSEITDKISHILYYGHFFCQVFHQDYIVKKGEDCADIEHAMWKILDSRHAEYPAEHNVGHLYYAKDSLKTHYHELDPTNSFNPGIGHTSKAAYWR
>NC_018145|1091000:1153371|1120494_1121244_+|WP_014848905.1|DBSCAN-SWA
MARSRNKASPSHPRFWGRHAVEAALNNPERHIRRIWATREALAPYDIDKSIPVTFSDVTDLGRFVPNDAPHQGIVIEVDPLPDIWLADLLDLPETDKRPLLVLDQVTDPHNVGAILRSAAAFDALGIITQDRHAPPESGALARAASGALEVVPWVRVTNLARALDEIAEAGYWRIGLTGHSEATLSQTLGSGKTALVLGAEGEGLRQNTEAHCDELAKLPISSKIESLNVSNAAAVALYAAAEKLNSQD
>NC_018145|1091000:1153371|1109845_1110682_+|WP_014848898.1|DBSCAN-SWA
MRNLLFSSCFLMACSTAFSPANAGITDPPSSSFTVSGSLSLFSDYRFRGLSRSNNHPAVQGTVTVAHKSGFYVGAWSSNLAGWGKMGDSKMELDVFGGYRHTLGAFTMDGGAIGYIYPAGGGGTKNNYFEIYGSASALVGPFTGKLGFNVAPPQHALGRYDLVSLSKHGDHSNVYAYGETDFAIPRTAAALHGHIGHTNGDAGFGPNFASLSPTGGYWDWKIGADYTFVKHVKVGVWWSDTNIDNKKFKSMWSSTDKGLGRNGSIAGSAAIFSLTLLL
>NC_018145|1091000:1153371|1108218_1108773_-|WP_011240190.1|protease|DBSCAN-SWA
MSEDKIGWHGTTILSVRRNGRVVIAGDGQVSMGNTVMKPNARKVRRLGDGSVIGGFAGATADAFTLFERLEAKLERHNGQLLRAAVELAKDWRTDKYLRNLEALMIVADDQVTLVLTGNGDVLEPVGGIAAIGSGGNFALSAARALVDYEEDAEVIARKALAVAADICVFTNDQVTIETLESRV
>NC_018145|1091000:1153371|1150543_1150975_+|WP_014848926.1|DBSCAN-SWA
MNTDYFTIGKLAKETDTKVVTIRYYESIGLLPAPLRTGHNYRLYNRDHFKRLSFIRRCRSLGFPLSQIREIIALTDQPDEDCQKVDKIARGHLDIIESKIQDLTQLASELRQKIIACQGGTIAQCCILKNLSKQNTTPIKSTP
>NC_018145|1091000:1153371|1125490_1128256_-|WP_014848910.1|DBSCAN-SWA
MTEYSDKPHLILIDGSGYIFRAYHRLPPLTNKAGLPAGAVYGFTTMLWKLVENIRKQDDAPTHFAVIFDSSRKSFRQDLYPAYKAHRPPPPEDLVPQFPLIREATRAFSVPSIEQEGLEADDIIACYSRVALERGFQVTVYSSDKDLMQLIQPRLNLFDPVNNCLIGSEQVVKKFGVVPEKLGDLLALMGDTADNIPGVPGVGPKTASRLINEYGNLSEILESAPEIKQPKLRQNLIEYKETAILSRELVALVDDKPLPEPLDNLVVKGVDMTPLRDFLSEQGFSSLLARAGGGQSAPVADGSKEMAASSSQRFDPDAYETVIDEKALDRWIADIYQKGQVAVDTETDNLDATQARLVGVSLSTEAGKACYIPCGHGGHDLLDQKPDQMDLSLLVKKLKPVLEDPSILKIGQNIKYDMIVLSRYGISVQPFDDTMLLSYDLDAGRHGHGMDELSLLYFDHQPISFKSVCGTGKSAITFNHVPIPAATRYAAEDADVTFRLWEILKPRLSSEGATRIYEEVDRPLPPVIARMEQAGITVDSAALRHLSFRFAHDISRLEEEIYVLAGCRFLISSPKQLGEVLFGTMGLAGGKKSKSGQYSTNVTELERLAAEGEVIASKILEWRQLSKLKSTYSDALIGKVNPETGRVHTSFSLVGAQTGRLSSTDPNLQNIPIRTEIGREIRNAFIAKKGHLLLSADYSQIELRLAAHVADEKALLQAFREKEDIHALTAKQLFGHVDRESRARAKTINFAILYGISAWGLAARLEIDRFSAQEMIDRYFERFPAIRHYIDRTLDFVRLHGYVETPFGRKTHLPAIKSRKVTERQAAERQAINAPIQGMSADIIKRAMVRMEPTLAKAGLSSVKMLLQVHDELIFEVPEEDIEKAKPVIRQVMMEAALPIVQLSVDLEVEIGTGISWGAAH
>NC_018145|1091000:1153371|1109307_1109583_+|WP_011240189.1|DBSCAN-SWA
MNSNDLVDRIASGQGLTKTDAKKLVDAVFSTIVDAAVAGEEIALNGFGKFKVKHSAARKGHNPATLQEIEIPASNRLTFTSAKAVKDRLNA
>NC_018145|1091000:1153371|1097712_1098469_+|WP_141914872.1|transposase|DBSCAN-SWA
MSDLYWLTEEQMDRLRPFFPKSHGKPRVDDRRVLSGIIFVNRNGLRWRDAPLEYGPHKTLYNRWKRWSAMGIFIRMMEGLATGKAEPQTIMIDATYLKAHRTASSLRFKKGGPGRLIGRTKGGMNTKLHAVTDRNGRPLDFFMTAGHISDYTGAAALLDSLPSAEWMLADRGYDADWFREALEEKGIKPCIPGRKSRSKPVKYDKRKYKRRNRIEIMFGRLKDWRRVATRYDRCPTVFFSAICLAATVLFWL
>NC_018145|1091000:1153371|1149844_1150477_-|WP_014848925.1|DBSCAN-SWA
MMGKKCCCEPDFSTKKAIPEGYKKALWAVFILNSMMFLAEIATGFFSKSASLQGDALDFLGDALNYAISLLVIGYSLRVTAWAAVLKGATMGLLGAWVLAITLWHIAHAIVPEATTMGIVGSVALLVNVVSFLLLWRFRSEDANMHSAWICSRNDVIGNCAVLLAAFGVFHWVKGWPDYSVAFIMALLALQGAWVSIRMALKELRSLSVC
>NC_018145|1091000:1153371|1145095_1145404_+|WP_014500625.1|DBSCAN-SWA
MFAIVRTGGKQYRVAAGDKIVVEKIAGEAGTTVSLEDVLLAGEGADLQPVKGLTVSAEIIAQAKAEKVIVFKKRRRHNYRRRNGHRQQHTILKIVSVGNAAA
>NC_018145|1091000:1153371|1122134_1122920_-|WP_014848907.1|DBSCAN-SWA
MIHLAAGNILFKTGSHQAAITLRGSCSFQGGILTGMIGANGAGKTTFLKILAGLQSPERGQVILNDRRLADLSPQQKAEAIAYLPQDRRIQWPVKACDLIALGRLRYGRSLNRLNQQDSHAIAHAVETTKTGDLLDRSMDSLSGGEQARILLARALAVDAPILLADEPLAALDPGYAMQIMEVLSQEAQKGRIVVVALHDLTLAARYCNRLLLWHRGEIVADGKPETVLTQDRLEQCYHIKAISQNYRGHWLVTPYDRVNS
>NC_018145|1091000:1153371|1128271_1129021_-|WP_014848911.1|DBSCAN-SWA
MSKTALITGATAGFGAATARLFVRHGWKVVATGRRRDRLDELVRELGEENLFPTVFDIRDESAMKEAMASLPSEFSEIDLLINNAGLALGTKPAPDIQLDDWRVMIDTNVTALAVITQHLLPKLIERQGMIINLSSVAAHWPYPGGNCYGGTKAFVRQFSYGLRCDLHGTGVRVTSIEPGLCESEFTLVRTKGDQKAYDETYKGAKALQPEDIAETLFWVASQPAHVNMNSIELMPVSQTWNPFRIYRG
>NC_018145|1091000:1153371|1111056_1111323_-|WP_011240187.1|DBSCAN-SWA
MAELHYELVTPSRLARSGDAFMVVVPGTEGDLGVMAGHMPTMTAIRDGEVAIYSSEHQIETKFHISGGFAEINEKGLIILAEEAKEEN
>NC_018145|1091000:1153371|1145535_1145805_+|WP_014848921.1|DBSCAN-SWA
MAHKKAGGSSRNGRDSAGRRLGVKKFGGESVIGGNIIIRQRGTKVYAGRNVGMGKDHTLFATAEGRVLFHKGKLGRSYVSVDALPLAAE
>NC_018145|1091000:1153371|1106449_1106617_-|WP_011240192.1|DBSCAN-SWA
MAKPTTVKIRLVSSADTGFFYVTRKNPRNQTEKMSLRKYDPVVRKHVEFKEAKIK
>NC_018145|1091000:1153371|1148917_1149841_+|WP_011240156.1|DBSCAN-SWA
MKIALTGGTGFIGGHVFDNTAGRGIGIKALTRRPQPARPGVEWIRGSLEDEDSLKKLVSSCQAVIHMAGAVKAENREAFAHINLTGTEKLLAATKAAGIKRFIHVSSLAAREAELSDYGWSKAQSEEKVRSSGLDWTIIRPPAVYGSGDREMLEMFRMAVMGLMIMPPKGRLSLIAADDLSRLILTLVDRDISQPSYHQLYEVDDGHPEGWSQNEFAQALGHAVGRPSIKVVHLPKKLLSFASKAEGWLHGNQARLTQDRVRYFCHPDWVINPTLRPPTTLWEPQIPLEEGLNQTAIWYRSRGWLKR
>NC_018145|1091000:1153371|1104199_1104956_+|WP_141914875.1|transposase|DBSCAN-SWA
MSDLYWLTEEQMDRLRPFFPKSHGKPRVDDRRVLSGIIFVNRNGLRWRDAPREYGPHKTLYNRWKRWSAMGIFIRMMEGLATGKAEPQTIMIDATYLKAHRTASSLRFKKGGPGRLIGRTKGGMNTKLHAVTDRNGRPLDFFMTAGHISDYTGAAALLDSLPSAEWMLADRGYDADWFREALEEKGIKPCIPGRKSRSKPVKYDKRKYKRRNRIEIMFGRLKDWRRVATRYDRCPTVFFSAICLAATVLFWL
>NC_018145|1091000:1153371|1122916_1123942_-|WP_014848908.1|DBSCAN-SWA
MRFFSGLSSFYKAHRLLINLSICLPPMALLSLSIGSTHIGVMALWQAVTGVGDPTSRLILGLLRLPRLCVGLAVGAILGMAGAVNQGYLRNPLADPSLLGTSNAAALGAVLAFYFGFSARFPICLPLFAFIGALAGLLPLLWFVRRHNDPQSLILGGVAIAAFSGACISLALNLSPNPFAAMEIMTWLMGAITDRSWNHVWLLIAPFFLSLFLFRRTAPALDALILGDDVAASLGFDLARLRWLIMAALAIGVGGAVAVSGAIGFVGLIVPHILRPFTRQLPSELLWPSAIGGALLVTLADILVRLLPTQNELQLGVVTAFIGVPIFFRQAIKGVGAMKSL
>NC_018145|1091000:1153371|1100888_1102637_+|WP_014848893.1|DBSCAN-SWA
MTWIFAFLAGLVAALGLQPYNLWGCSLVAVAGWLALLRQTQKTWQIFALSWLFAFGFFWLGLDWIATSFTHQAAMPSWLGWVAVPLLSCYLACYIALFTLPLRFLCLSFQRGKKRADSFQSSDVTLDGADSGDVDAIPSRLFPVGNEAVARERKIKSRFFVGSAAFWSVPVFNISLSQRPLWRLTLALAGCLAWGEWIKSWVFTGFPWSPLGAIWLNVMPIAHIARWIGSYGLSALVVIAAGIGLSCYDGIKSAIEKRQARQAIRSILPAFWMALPFLGWALVDGHDIHWQKSEQPPAHVVIVQPNIPQDEKYDLRYKSRHDAIFEKLSGKGDPHHPRLILWPEDAVQSYLEEEPLARAALSRLLGKNDLLLTGGDALIPDNSGHIASVRNSLFVLGAKGDILDRYDKAHLVPFGEYMPFRKWAAYVGLGRLVAGDIEFTEGAQPESLDLSPFGLVGIQICYEIVFSGRVVDRVHRPDFIFNLSNDSWFGRSGPPQHLAQARLRAIEEGLPIARATSTGISAVIDAEGRILQFLPENTEGRLLAVMPKALQPTFFARHGNLISVLFATALLLIALFGRIKLR
>NC_018145|1091000:1153371|1138829_1139480_-|WP_014848918.1|DBSCAN-SWA
MSVASSSLFSVSDLLKEGDTSDNIQPTASMADKKSLRKLFRQRRKALADHPSWKADGLIFTLMLAEHIRSHFGKARSISAYLPNDGEVDPLPIFLQAIDAGITPLLPRIVEKDAPLDFHRWWPDDPLEEKNGGILQPVAESEKIVPDIILTPLVGFDRSLRRLGRGGGYYDRSFKAYPDAIRIGVAWSIQEAEAIPVEAWDMPLHAVATEKEWIGF
>NC_018145|1091000:1153371|1105341_1105800_-|WP_011240194.1|DBSCAN-SWA
MTIETRLAELGILLPEAAAPVAAYAPTVLAGNLLHISGQLPFLEGQLMTGRLGEDRDEAYGFRAAERCAIMLMAQMKAALTSLDRVEKIIKLNAFVNSAPSFTRQAQVVNGASELLAKVFGDAGVHARSAVGVAVLPLNAPVEIDAVVAVRP
>NC_018145|1091000:1153371|1147727_1148921_+|WP_014848924.1|DBSCAN-SWA
MVADLTSDISESQEQETETNSANNNGAVFRPENCPRLVIKIGSSLLVDQRGQVRRDWLQTVAYDIAKLHQAGQQIIVVSSGAIALGARRLNLPRGGRASLEDAQASASVGQILLSQCWAELLGACSLDSSQILLTLDDLEDRRRYLNVSATLDRLLSLGVVPVINENDSIATAEIRFGDNDRLAARIGQASHASGVILFSDVDGLYTANPMKDPNAKRIDRVEHIDNSTEAMASSDSASGMGSGGMASKVEAARIATYSGVNLAITTGKRPSPLTMFLNDGAGTLFTADESASAHKTWLAGRLTAHGQVYIDQGAVEALHDGNSLLPAGVCSIEGKFNRGDVVDILDQEHNLIARGLIEYDSEDSAQITGKRSQEIADILGYEARTALIHRNHMVML
>NC_018145|1091000:1153371|1145999_1146608_+|WP_014848922.1|DBSCAN-SWA
MFAYSARLFLRPLWSDDLGVLLDLLDTASSRSGLLDSPDNDVTRYLRGNAARLIHENDVTRPHSGIFLRDGKEPRLIGITALAGKEAHFFCWIAPAFRRQGFATEASRLMLHFADEALRLPSLTAAYDHADAAAEKLLTKLGFSEKQKTPPTAAWGAANTSVSFLPENFIKEERVRVFSSCQPSLQHSKSQTISNRSATLAA
>NC_018145|1091000:1153371|1132541_1133096_-|WP_011240168.1|DBSCAN-SWA
MASKALSFVVGDYVVYPKHGVGRVVELQSQEIAGTRLELYVLRFEKERMTLRVPTNKAEAVGMRKLSSSATLQEAIQTLKGKPRIKRTMWSRRAQEYETKINSGDLVSIAEVVRDLFRADDQPEQSYSERQIFEGAASRLARELGAMENTDEAQALDKIFDVLKAAAAEHRQAVKELAKEEAVD
>NC_018145|1091000:1153371|1131176_1131938_-|WP_014848914.1|DBSCAN-SWA
MRDRYKIGCCLLFIIAAFAVITVKVWPSFSGRIDQSYHFQPFDTLYLAGIDDAEIILGDDYSVNLQVAPKAVKSLDIEFKNNSLNILYKKNWLNYLDFHKSPVKIRITLPVLKECVSSGAGFVSIEGEVRNPLTVILNGSGKINVSSAIRDNLTAILNGSGAISFSDIHADKVVSDIMDSGQITFAGDSQSATFRLMGSGKMDVSKFQSQTVNLSLMGSGDIEVKPDADMSRWKISKMGSGNIRQQKAIPLKG
>NC_018145|1091000:1153371|1094617_1096075_+|WP_014848889.1|DBSCAN-SWA
MASASSPSGGRKPFFSRFFRRKKIEKIGNPVGENNSQEPVIRPTGSLTRRLIAISALWIFILLSGGGVTLDRVLTQAVTDNFDSQLDYVLAAMIASSEIDPEGAVRLNRPLGDQRFLEAHSGLYFQVSGSGYERFPSPSLWDRSLQVNPMPKGQLVRTYDSDEFSDGTLRVMERDVRLPGSSVLWRFQVAEIRTSLDNQIKKLRHTLVKAFLILGTGLIVITVLQVTIGLWPLRKLRREISAVRNGQASRIHDRMPNEVAPLIEELNALLSHNERQAEEARRHAGNLAHALKTPLTVVTNEANANSDALKEVVLREVMTMRRHVDHHLARARAIGRRGNAQSQAEVWPALLAVERAVTRLYPHATIDLAGVKDAVVRIERQDLDEILGNLIENAAKYGQGRVFVTVEKQGKQVEILIEDDGTGIPENLRGQLFKRGARLDTDKPGTGLGLAIVRDVVEIYGGGVTLEESEDLGGLFVRLALPSVN
>NC_018145|1091000:1153371|1121360_1121909_-|WP_014848906.1|DBSCAN-SWA
MNSPKKPANGAMALVEMKEFATFPAATQRYIRRSLDIGLKRHEVLERWSRDVIEAASIRAQTQVYHHLDTVRHHLPDDNGLESLQHFMTPLIIMSAFDLGQDRLNSFSAYRFLYERLIGAAVRPWLPSAFCASAALPHLHPEKRRALLQSISEAAVTAPGWSNRPPCFIPEWVEKVQQPLPN
>NC_018145|1091000:1153371|1133994_1136826_-|WP_014848916.1|DBSCAN-SWA
MSRLSSSSSVIAVLGPTNTGKTHLAVQRMCSYTSGVIGFPLRLLAREVYDRVVEIKGADRVALITGEEKILPEKAQYFLCTAESMPMNRDFAFAALDEVQLGCDRERGHVFTDRLLNLRGREETMFLGSDALRPLLRRLIPGIEIVSRPRFSTLSYSGPTKLSRLPPRSAVVAFSAEEVYATAEMLRRLRGGAAVVMGALSPRTRNAQVEMFQAGEVNYLVATDAIGMGLNMDVTHVAFASLTKFDGRQVRRLTIPEMAQIAGRAGRYQRDGSFGVLQWPGETLEFREEEVLAIEEHHFSPAEYLYWREGQPDVSRLDALIASLERKPGLPLLRAAPESYDLAVLHKLAEDPVIKDRTRSSLAVKRLWAVCGLPDFRKTGIEAHSRLVRRIFGYLTEGNGYLPVSWFADEIVKLDNVQGDVPTLSERLAGIRIWAYIAHRSDWLENPAKWAERTRALEEKLSDALHERLTQRFVDRRTSILMQDMGKAALDMLPTEFSEDGVVLVGGESIGRLDGFSFHVDPAARHGDMKRLHAAAERRLGGELTRRAKALQEDEDKAFSLLTAKGEKIGISWHGYPVADLERGKSFLTPRIKLSRKLDRLSPIDQKQIEERLVTWLKGNIEQTLGSLVKLAELSELSTTPPSLRALLASLVEKGGCLPRVEIDDILKMLNRPLKKQAAVLGIRFGRLDIFMPALLKPKAIDWRLALLAVFHNRLLSFIPKNRGSAIETPLESDAAEMAGWVGFRSLGSQMLRVDSAEKLATMVHDRRPSQKTDKNATHNKIDPSHPSSGQKIEKKVASPLSKRVKKKADDSAMEAVKKDTPRKVKVAESLPIPAKKQPKKGDQKKKEKIPQSQDNTLRQPSFAPDQRMMQAMGLKPDAFAKLMLKLGFYPADKKQKKDSSIKEDKPQWVWRGVKRGSQRRRASFKKQPDIPNAFSVLAHLKK
>NC_018145|1091000:1153371|1129399_1130521_+|WP_014848912.1|DBSCAN-SWA
MNNDRRFGLKRHITLPGELALDGGSLLTGIEIAYETYGHLNADASNAILICHPLTADQFAASDHPITGKPGWWSRMIGKGKPIDPERYCIICSNVLGSCLGSTGPSSFTPGTATPYAMNFPVITIRDMVRAQAKLLDYLGIRQLKAVIGGSMGGMQALEWASTYPDRVKSVVIIASTARHSAQNIAFHEVGRQAIMADPKWRQGNYYEEKDPPVAGLAVARMAAHITYLSESGLTARFGRRLQSRQEKSFGFDADFQIESYLRHQGIRFVERFDANSYLYITRATDYFDLAEEHGGKLANAFRGTKSRFCVISFDSDWLYPTSESRVIVHALNAAGAAVSFMELSNPNGHDSFLLDAPDLHRTVHGFLEGDRA
>NC_018145|1091000:1153371|1132017_1132317_-|WP_014848915.1|DBSCAN-SWA
MSAYVISDTNPKDPDAWKIYIELAAAAIKQYGGRYLSRGNEIDVIEGEWTPRAIVVIEFPDMATAKTWYASPEYGKALVYRDKALKRNLIFIDGYKGEN
>NC_018145|1091000:1153371|1096933_1097581_+|WP_181406055.1|DBSCAN-SWA
MIRLLLLIRRDCSILIGAGVFLPVLFFLLVAVLYPFAVGSDAIILSRTGSGILWVAALLASLLPIDRLIIPDVENGFFDYYAVRGISEEWIAVARIIAHWVSFAVPLMVALLPASALLSLNWSVFWKLEAGFLLSTPGLASLGVMIAALTARIKSGSGLAALLLLPLAVPLLIFGAGAVDGHQPGAFLLLAACSLFLLAVAPFVIGAALRVGQDG
>NC_018145|1091000:1153371|1112865_1113762_-|WP_011240185.1|DBSCAN-SWA
MPSLKSLKTRVSSIKSISKITRAMQMVASAKLRRAESRLAAARPYAKRMAQVMSLLAARAAGTPNALPLLNGRGKDQTHLLIVTSSDAGLCGGFNSNIYRQARDRALALEAAGKTVQFYVIGIKNAPVIRNNFPGKTIHETKREETSPVTFENAQKIAQDLIQRFNAGEFDVAHLFFSHYHSVLSQVPTETQIIPAAPEGDDTKNQAAANDASSGAIEFEPDEETILSTLLPRSIAVAIYQAMLENATSEQGSRMSAMENSTRNAGEMISKLSIQYNRLRQAAITTELVEIISGAEAL
>NC_018145|1091000:1153371|1130520_1131168_+|WP_014848913.1|DBSCAN-SWA
MSLKDPQILEDPSVKLSLSMQPERPDFAIISNHIIPESRVLDIGCGDGALIASLKKSKNIDARGIEINPANVGHAVARGLSVIQGDADTDLINYPDQAFDFVILSQTLQTTRAPHQVLNQLLRIGRYAFVSFPNFAYWKVRMALMLRGRMPVTPNLPISWYETDNIHMLTIEDFYDFTAQHRYQVKESWFFSHNRQISATAANWRAESALFLLHR
>NC_018145|1091000:1153371|1146699_1147743_+|WP_014848923.1|DBSCAN-SWA
MQFLDQAKIYLRSGAGGPGAVSFRHEKYIEYGGPDGGNGGKGGDIVFEAVPGLNTLIDFRYTQHFRAARGASGAGSNKTGAGAKDLVIHVPVGTQVLSEDKEEILHDFTKVGEKVIFLKGGDGGRGNASYKSSTNRAPRQHGPGWPAQEAWVWLRLKLLADVGLVGLPNAGKSTFLKATTNAHPKIGNYPFTTLFPQLGVVRRHGQEFVLADIPGLIEGASEGIGIGDRFLGHIERCRILLHLIDASGEDPIAAWHEVQNELALYGAGLAEKPQLLALNKIDSVDEETCAELSQALEEASGQKVLLLSGATGQGLDPILDQLITMTGRAMEKAQESSAQTEKIWSPI
>NC_018145|1091000:1153371|1106901_1108194_-|WP_014848897.1|protease|DBSCAN-SWA
MTDALTPKAIVEALDAHIVGQKEAKRAVAVAMRNRWRRQNLPEHLKDEVNPKNILMIGPTGCGKTEISRRLAKLANAPFIKVEATKFTEVGYVGRDVEQIGRDLVEEAVRLEREKQRALVREKAEQAAMERLLDALVGKDASEATRETFRQRFLDRHLDEREVELELEEAPSMPVEIPGMGGQVGMISLSDMLGKGHRTKRQRLPVRQAWRRLIDEEADRRLDKDEIGRIALSNAEANGIVFLDEVDKIAVSDVRGGSVSREGVQRDLLPLLEGTTVTTKYGPMKTDHVLFIASGAFHVAKPSDLLPELQGRLPIRVELSALTEDDFIRILSSTRASLVEQYRALIGTENVVLHFEEDGIRQLAHIAAEVNSEVENIGARRLSTVMEKLLEDISFNAEDMHGEEIKIDKKYVDERLSGIAKNSDLSKYIL
>NC_018145|1091000:1153371|1102829_1104005_+|WP_014848894.1|DBSCAN-SWA
MRSNYLFTSESVSEGHPDKVADQISDAIVDLYLSRDPEARVACETLVTTQRIIIGGEVRSAVPVSEEEIEKTVRETVREIGYEQTGFDWKTAEFANHLHAQSADIAQGVDAGEDKDEGAGDQGIMFGFATDETPDYMPATLYYAHRILERLAEDRHQKKVDFLEPDAKSQVTLVYENGVPVRASALVLSTQHSPALSSKEGQAKLRDYVKSVYEDVLPKGWMPDDKAIFVNPTGLFEIGGPDGDAGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYVARYLAKNIVAAGLAKKVTIQLSYAIGVSEPLSLYVDTHGTGTVDEAKIEEVLPKLIRLTPKGIRTHLKLNKPIYKPSAAYGHFGRKADGDFFPWEKLDLVDKLKAAFA
>NC_018145|1091000:1153371|1119545_1119932_+|WP_014848904.1|DBSCAN-SWA
MSNPVQKFFSHVFKGDIQGALQFVHENAVFEAQGPSDVPIYGRYNGHEGVMRFLSILSGLFDTEDFKCFEWSDSENYVFGYGYMQHRVKKTGKLFKSEWALVCKIENNLIISYKIFEDTAALQSAYKD
>NC_018145|1091000:1153371|1117878_1119453_+|WP_041572962.1|DBSCAN-SWA
MRYAYAVTAALLIGGATATMVTQQPVDAQVAQNAPGTIHAPVSKNGTIPGFADLVEKLQPAVVNISTTQRVKIQTPANPFAGTPFADLFGGLGGGDTGRPITREAQSLGSGFIVSPDGFVVTNNHVISAGDPDKQGSGTASAVVESITVTLPDHGEYKARVVGRDSASDLALLKIESAKPLPFVQFGDSTRTRVGDWVLAIGNPFGFGGSVTAGIVSAMHRGVGSGPYNRYIQTDAAINQGNSGGPMFDVNGNVIGINTAIWAPSGGNIGIGFAIPAEIAKPVIDTLRSGKKVRHGYLGIAIQVLTDDIAAGLGLPKDHGEIVVRVEPGGPGFKAGIRQGDVLVKVNNIDVTPDNTLSYLVASQPVGAKVPIEVIRNGKHMTLSAVLAERPPEDQLASNGVPNNDDSDDDSNQNTPRNSARTALGITLEPVTPEVANRLNIPQNSHGLWISNVDQSSDAAEKGLRRGDVILSMNEHPVTSIGDAVAAINATKAAGRNTVLILVQRGNNPPLFTGLKLMSPTKNK
>NC_018145|1091000:1153371|1091000_1091760_-|WP_014848895.1|transposase|DBSCAN-SWA
MSDLYWLTEEQMDRLRPFFPKSHGKPRVDDRRVLSGIIFVNRNGLRWRDAPREYGPHKTLYNRWKRWSAMGIFIRMMEGLATGKAEPQTIMIDATYLKAHRTASSLRLKKGGPGRLIGRTKGGMNTKLHAVTDRNGRPLDFFMTAGHISDYTGAAALLDSLPSAEWMLADRGYDADWFREALEEKGIKPCIPGRKSRSKPVKYDKRKYKRRNRIEIMFGRLKDWRRVATRYDRCPTVFFSAICLAATVLFWL
>NC_018145|1091000:1153371|1093937_1094615_+|WP_011240200.1|DBSCAN-SWA
MRVLIVEDEPTLSRQLRTTLEGAGYAVDLATDGEDGHFLGSSENYDAVVLDLGLPEVDGLTVLDRWRKEGREMPVLVLTARDSWSDKVAGLDAGADDYLTKPFQTEELIARLRALIRRASGNASSELTAGDVRLDTRSGKVTLAGEPVKLTAQEYKLLSYLMHHKGKVVSRTEMIEHIYDQDFDRDSNTIEVFVTRIRKKLGQDVITTIRGLGYALNDPEDRNNG
>NC_018145|1091000:1153371|1111382_1112837_-|WP_014848899.1|DBSCAN-SWA
MATASSKKNIGRISQVIGPVVDVLFEEKLPPLLTALETQNQDATVVLEVAQHLGENVVRTISMETTDGLVRGQEVVDTGSEIRVPVGPETLGRIMNVVGRPVDERGPIGSKQTMPIHADAPAFTEQSTDIAILTTGIKVIDLLAPYSKGGKVGLFGGAGVGKTVLIQELINNIAKGHGGFSVFAGVGERTREGNDLYHEFLEAGVIASDKDGNAISEGSKVALVYGQMNEPPGARARVALSGLTMAEYFRDQEGQDVLFFVDNIFRFTQAGAEVSALLGRIPSAVGYQPTLATDMGQLQERITSTKKGSITSVQAIYVPADDLTDPAPAASFAHLDATTVLSRAISEMGIYPAVDPLDSSSRNLEPRIVGDEHYQTARDVQEILQRYKNLQDIIAILGMDELSEDDRKVVGRARRIQRFLSQPFHVAEVFTGMPGKFVQVEDTVRSFREIIDGKYDDLPENAFYMVGSIDEVVAKAEKMAAEAA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014848895.1|1091000_1091760_-|transposase	IS5 family transposase	A0A0N9SJT9	Paenibacillus_phage	5.9e-11	38.8
WP_014848888.1|1091989_1093714_+	D-lactate dehydrogenase	NA	NA	NA	NA
WP_011240200.1|1093937_1094615_+	response regulator transcription factor	NA	NA	NA	NA
WP_014848889.1|1094617_1096075_+	sensor histidine kinase N-terminal domain-containing protein	W8CYF6	Bacillus_phage	4.5e-07	22.8
WP_014848890.1|1096271_1096937_+	heme ABC exporter ATP-binding protein CcmA	A0A1V0SGN0	Hokovirus	3.7e-09	28.8
WP_181406055.1|1096933_1097581_+	heme exporter protein CcmB	NA	NA	NA	NA
WP_141914872.1|1097712_1098469_+|transposase	IS5 family transposase	A0A0N9SJT9	Paenibacillus_phage	5.9e-11	38.8
WP_041572956.1|1100055_1100256_-	hypothetical protein	NA	NA	NA	NA
WP_014848893.1|1100888_1102637_+	apolipoprotein N-acyltransferase	NA	NA	NA	NA
WP_014848894.1|1102829_1104005_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	9.5e-101	51.2
WP_141914875.1|1104199_1104956_+|transposase	IS5 family transposase	A0A0N9SJT9	Paenibacillus_phage	5.9e-11	38.8
WP_011240194.1|1105341_1105800_-	RidA family protein	M1I5B0	Acanthocystis_turfacea_Chlorella_virus	7.1e-20	38.5
WP_012817423.1|1105971_1106334_+	response regulator	NA	NA	NA	NA
WP_011240192.1|1106449_1106617_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_014848897.1|1106901_1108194_-|protease	ATP-dependent protease ATPase subunit HslU	A0A2H5BJT2	Erwinia_phage	1.2e-35	27.2
WP_011240190.1|1108218_1108773_-|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_011240189.1|1109307_1109583_+	HU family DNA-binding protein	Q6QIE5	Burkholderia_phage	7.3e-12	43.7
WP_014848898.1|1109845_1110682_+	hypothetical protein	NA	NA	NA	NA
WP_011240187.1|1111056_1111323_-	ATP synthase F1 subunit epsilon	NA	NA	NA	NA
WP_014848899.1|1111382_1112837_-	F0F1 ATP synthase subunit beta	NA	NA	NA	NA
WP_011240185.1|1112865_1113762_-	F0F1 ATP synthase subunit gamma	NA	NA	NA	NA
WP_014848900.1|1113795_1115325_-	F0F1 ATP synthase subunit alpha	NA	NA	NA	NA
WP_014848901.1|1115327_1115882_-	F0F1 ATP synthase subunit delta	NA	NA	NA	NA
WP_014848902.1|1116315_1117344_-	P-loop NTPase	NA	NA	NA	NA
WP_041572962.1|1117878_1119453_+	Do family serine endopeptidase	A0A1B1IT49	uncultured_Mediterranean_phage	5.1e-25	25.7
WP_014848904.1|1119545_1119932_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_014848905.1|1120494_1121244_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_014848906.1|1121360_1121909_-	hypothetical protein	NA	NA	NA	NA
WP_014848907.1|1122134_1122920_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.0e-07	24.7
WP_014848908.1|1122916_1123942_-	iron ABC transporter permease	NA	NA	NA	NA
WP_014848909.1|1123946_1125494_-	lipopolysaccharide biosynthesis protein	NA	NA	NA	NA
WP_014848910.1|1125490_1128256_-	DNA polymerase I	A0A142F1Q9	Bacillus_phage	1.5e-64	31.4
WP_014848911.1|1128271_1129021_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_014848912.1|1129399_1130521_+	homoserine O-acetyltransferase	NA	NA	NA	NA
WP_014848913.1|1130520_1131168_+	methionine biosynthesis protein MetW	NA	NA	NA	NA
WP_014848914.1|1131176_1131938_-	DUF2807 domain-containing protein	NA	NA	NA	NA
WP_014848915.1|1132017_1132317_-	DUF1330 domain-containing protein	NA	NA	NA	NA
WP_011240168.1|1132541_1133096_-	CarD family transcriptional regulator	NA	NA	NA	NA
WP_011240167.1|1133425_1133764_-	ferredoxin family protein	NA	NA	NA	NA
WP_014848916.1|1133994_1136826_-	helicase	A0A248SJQ0	Salicola_phage	1.7e-26	34.0
WP_014848917.1|1137178_1138750_+	M23 family metallopeptidase	A0A7K9	Microcystis_virus	2.0e-21	48.7
WP_014848918.1|1138829_1139480_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_014848919.1|1139704_1141150_+	MATE family efflux transporter	NA	NA	NA	NA
WP_014500625.1|1145095_1145404_+	50S ribosomal protein L21	NA	NA	NA	NA
WP_014848921.1|1145535_1145805_+	50S ribosomal protein L27	NA	NA	NA	NA
WP_014848922.1|1145999_1146608_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_014848923.1|1146699_1147743_+	GTPase ObgE	NA	NA	NA	NA
WP_014848924.1|1147727_1148921_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	5.4e-59	40.2
WP_011240156.1|1148917_1149841_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_014848925.1|1149844_1150477_-	cation transporter	NA	NA	NA	NA
WP_014848926.1|1150543_1150975_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_141914866.1|1152614_1153371_+|transposase	IS5 family transposase	A0A0N9SJT9	Paenibacillus_phage	2.9e-10	38.8