CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_018289	Mycolicibacterium smegmatis MC2 155, complete sequence	1 crisprs	csa3,WYL,cas3,cas4,DEDDh,DinG	0	2	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_018289_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018289_1

954370-954618

Orphan

Consensus_repeat	Method
NNNCCGCCGTTGCCGCCG	CRT

4 spacers

The CRISPR arrays of NC_018289_1

>merge|NC_018289|1|954370-954618|CRT
TCACCGCCCTTGCCGCCCCTGTGCCCGTCGGCGTCACCGTTGCCGCCGTTGCCGCCGTTGCCGCCGGTCGCCGTGCCGGTCGCGGTTCCGTTGTTGACCCGGATCCGGCCTGCGCCGCCGTTGCCGCCGTTGCCGCCGGCACCCGTGTGCGATGGGTCGACGTACGTGCCGCCGTTGCCGCCGTTTCCACCGTTGCCGCCCTTGCCGCCGTTGCCGAGGCCGACTCCGCCGGTCCCGCCGTTGCCGCCG

>NC_018289|1|1|954370-954618|CRT
TCACCGCCCTTGCCGCCC	CTGTGCCCGTCGGCGTCACCGTTGCCGCCG
TTGCCGCCGTTGCCGCCG	GTCGCCGTGCCGGTCGCGGTTCCGTTGTTGACCCGGATCCGGCCT
GCGCCGCCGTTGCCGCCG	TTGCCGCCGGCACCCGTGTGCGATGGGTCGACGTAC
GTGCCGCCGTTGCCGCCG	TTTCCACCGTTGCCGCCCTTGCCGCCGTTGCCGAGGCCGACTCCGCCG
GTCCCGCCGTTGCCGCCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_018289.1\|WP_011727255.1\|960096_961071_-\|xanthine-dehydrogenase-family-protein-subunit-M	unknown	unknown	gnl\|CDD\|224238
NC_018289.1\|WP_011727251.1\|951219_952926_-\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|223989
NC_018289.1\|WP_011727250.1\|948882_950382_+\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|225962
NC_018289.1\|WP_011727261.1\|965333_966251_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|235737
NC_018289.1\|WP_003892291.1\|950407_951223_+\|HAD-IIA-family-hydrolase	unknown	unknown	gnl\|CDD\|319812
NC_018289.1\|WP_011727263.1\|968916_969750_+\|DUF559-domain-containing-protein	unknown	unknown	gnl\|CDD\|380141
NC_018289.1\|WP_011727254.1\|957934_960100_-\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	unknown	unknown	gnl\|CDD\|224446
NC_018289.1\|WP_011727246.1\|945458_946157_-\|phosphatidylserine-decarboxylase	unknown	unknown	gnl\|CDD\|235400
NC_018289.1\|WP_003892307.1\|967146_968772_+\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NC_018289.1\|WP_011727260.1\|964404_965337_+\|dihydrodipicolinate-synthase-family-protein	unknown	unknown	gnl\|CDD\|223406
NC_018289.1\|WP_036462586.1\|961074_961524_-\|(2Fe-2S)-binding-protein	unknown	unknown	gnl\|CDD\|224991
NC_018289.1\|WP_011727249.1\|948346_948886_+\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|225937
NC_018289.1\|WP_011727258.1\|962228_962933_+\|FadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225097
NC_018289.1\|WP_011727248.1\|947385_948309_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|235737
NC_018289.1\|WP_011727244.1\|941352_942366_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176867
NC_018289.1\|WP_014876895.1\|946192_947380_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NC_018289.1\|WP_011727245.1\|942362_944600_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|273521
NC_018289.1\|WP_029104365.1\|966355_966919_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NC_018289.1\|WP_011727259.1\|963004_964408_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|179668
NC_018289.1\|WP_003892285.1\|944601_945462_-\|CDP-diacylglycerol--serine-O-phosphatidyltransferase	unknown	unknown	gnl\|CDD\|224104

Protein	Function_ID	Function_description	E-value
NC_018289.1\|WP_011727255.1\|960096_961071_-\|xanthine-dehydrogenase-family-protein-subunit-M	gnl\|CDD\|224238	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion].	2.03478e-68
NC_018289.1\|WP_011727251.1\|951219_952926_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	2.41446e-69
NC_018289.1\|WP_011727250.1\|948882_950382_+\|PH-domain-containing-protein	gnl\|CDD\|225962	COG3428, COG3428, Predicted membrane protein [Function unknown].	1.4792e-98
NC_018289.1\|WP_011727261.1\|965333_966251_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|235737	PRK06197, PRK06197, short chain dehydrogenase; Provisional.	0
NC_018289.1\|WP_003892291.1\|950407_951223_+\|HAD-IIA-family-hydrolase	gnl\|CDD\|319812	cd07509, HAD_PPase, inorganic pyrophosphatase similar to a human phospholysine phosphohistidine inorganic pyrophosphate phosphatase (LHPP). LHPP hydrolyzes nitrogen-phosphorus bonds in phospholysine, phosphohistidine and imidodiphosphate as well as oxygen-phosphorus bonds in inorganic pyrophosphate in vitro. This family also includes human haloacid dehalogenase like hydrolase domain containing 2 protine (HDHD2) a phosphatase which may be involved in polygenic hypertension. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	5.31982e-89
NC_018289.1\|WP_011727263.1\|968916_969750_+\|DUF559-domain-containing-protein	gnl\|CDD\|380141	pfam18741, MTES_1575, REase_MTES_1575. Vsr REase Fold. Fused to HEPN (SWT1/Abi2 family), along with Transglutaminase and wHTH.	2.23847e-05
NC_018289.1\|WP_011727254.1\|957934_960100_-\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	gnl\|CDD\|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	2.94144e-168
NC_018289.1\|WP_011727246.1\|945458_946157_-\|phosphatidylserine-decarboxylase	gnl\|CDD\|235400	PRK05305, PRK05305, phosphatidylserine decarboxylase family protein.	4.09711e-99
NC_018289.1\|WP_003892307.1\|967146_968772_+\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NC_018289.1\|WP_011727260.1\|964404_965337_+\|dihydrodipicolinate-synthase-family-protein	gnl\|CDD\|223406	COG0329, DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane].	9.33576e-80
NC_018289.1\|WP_036462586.1\|961074_961524_-\|(2Fe-2S)-binding-protein	gnl\|CDD\|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	1.07744e-76
NC_018289.1\|WP_011727249.1\|948346_948886_+\|PH-domain-containing-protein	gnl\|CDD\|225937	COG3402, COG3402, Uncharacterized conserved protein [Function unknown].	4.05291e-34
NC_018289.1\|WP_011727258.1\|962228_962933_+\|FadR-family-transcriptional-regulator	gnl\|CDD\|225097	COG2186, FadR, Transcriptional regulators [Transcription].	6.11222e-47
NC_018289.1\|WP_011727248.1\|947385_948309_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|235737	PRK06197, PRK06197, short chain dehydrogenase; Provisional.	0
NC_018289.1\|WP_011727244.1\|941352_942366_+\|SRPBCC-family-protein	gnl\|CDD\|176867	cd07825, SRPBCC_7, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	2.78889e-61
NC_018289.1\|WP_014876895.1\|946192_947380_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	1.66288e-156
NC_018289.1\|WP_011727245.1\|942362_944600_-\|AAA-family-ATPase	gnl\|CDD\|273521	TIGR01243, Cell_division_cycle_protein_48_homolog_MJ1156, AAA family ATPase, CDC48 subfamily. This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.	3.85813e-124
NC_018289.1\|WP_029104365.1\|966355_966919_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.26703e-11
NC_018289.1\|WP_011727259.1\|963004_964408_+\|MFS-transporter	gnl\|CDD\|179668	PRK03893, PRK03893, putative sialic acid transporter; Provisional.	0
NC_018289.1\|WP_003892285.1\|944601_945462_-\|CDP-diacylglycerol--serine-O-phosphatidyltransferase	gnl\|CDD\|224104	COG1183, PssA, Phosphatidylserine synthase [Lipid metabolism].	1.39396e-59

>NC_018289.1|WP_011727251.1|951219_952926_-|DEAD/DEAH-box-helicase
MRADSAPSTQALRGWQRKALVKYLTTKPRDYLLVATPGAGKTTFALRIAAELLADRTVDKITVVVPTEHLKIQWAASAARNGISLDPKFSNSNSQTSSEYDGVVVTYAQVASHPTRHRVRTENYRTLVIFDEIHHGGDAKSWGDAMREAYSDATRRLALTGTPFRSDDSPIPFVNYEPDESGFMRSQADHVYGYADALADGVVRPVVFLAYSGEARWRDSAGEEHAARLGEPLTAEQTARAWRTALNPAGEWMPAVIKAADRRLEQKRQHVPDAGGMIIATNQTTARAYADLLTKITGETPTVVLSDDPSASDRISQYSESNSKWLVAVRMVSEGVDVPRLSVGVYATSASTPLFFAQAIGRFVRSRRQGETASIFLPSVPNLLLLASEMEAQRNHVLGKPHRESDGLDDAALEEAEKRKDEKSELENGFEYLGADAELDQVIFDGASWGTATPAGSDEEADYLGIPGLLDAEQMRDLLRRRQEEQLTKRTAVAAETGAPPPPRTTHGQLRELRKELNALVTIAHHRTGKPHGWIHNELRRICGGPPVAAATTEQLKERIEAVRRLNP
>NC_018289.1|WP_003892291.1|950407_951223_+|HAD-IIA-family-hydrolase
MAIGGVLFDIDGVLVTSWQPIEGAAQTLRVLADNQIARSYLTNTTTKTRVQIAELLTAAGMDVSPDEVITAAVLTAEYVRDRFPGARCFLVNSGRIDEDMPGVDVVYSSEFSGPRAPEAPDVVLLGGAGPEYSHLTLSWVYDWMAQGVPVVAMHRSTSWTTTDGLRVDTGMYLIGMEETSGRKATAVGKPAPEGFLAAASRLGVDPDEMYMIGDDLNNDVLAAQVVGMTGVLVRTGKFRQSVLDRWAADDFAMQPNHVIDSVADLPALLGL
>NC_018289.1|WP_011727250.1|948882_950382_+|PH-domain-containing-protein
MTAPPQPPGAGPQWQRLSPRMLLVHPVHEVLQQIPLLVGSVVLGSATGNPLWTVAAIVLTILFGLARWFTTTYRIEPNEVQLRTGVLQRKVLAVPRNRIRSVSTDARLLHRVMGLTVLRISTGQEAKGDAEFALDAVEAGQVPRLRAILLADLADASPEEHVPAGRELARWQPAWLRYSPLSFTGLAMILAAFGIVYQAGAGALMRDSAFAQSGLDAAERLGVAVSIAIVVGAVLVASVVLSVLRSLLTYGNLVLTRRDGPGGDGVLHLQHGLLRVREHTYDMRRLRGGTLREPLLVRVFGGARLDAVMTGIGGEGEASLLLPPCPAATARGVLTALIGRPDAVSGPLRPHGPAATRRRWTRALVLPVIALPVLAVVGVPVWAWVLWALVTVAAALLAADRSRALGHRVDGDWLVAQAGSVERRRDCLHTDGIIGWTVRQTLLQRRAGVATLIAATAAGQKRYEVIDVPAGQAWAIAAAGTPWIADSVWAHTPVGSDLR
>NC_018289.1|WP_011727249.1|948346_948886_+|PH-domain-containing-protein
MDREGEEYSGSTASGLVLLDPSNPPSRKAPLAWAMGAAIPWSMLVFGQLVWLLFDRRMLWLHGLAAVATAAGIVLFVVIVPLWRYRVHRWDISVDTATPAVYTRTGWLVQERRIAPISRVQTVDTYRGPLDRLFGLANVTVTTASSAGAVRIVALDVDVADRVVALLTDIAAIGEQDAT
>NC_018289.1|WP_011727248.1|947385_948309_-|SDR-family-NAD(P)-dependent-oxidoreductase
MSADTKWTEADVPDQSGRVAIVTGSNTGLGYETARALAAKGAHVVIAVRNLDKGRDAVDRIMASTPKADLKLQKLDVGSLDSVRTAADELKGAYPHIDLLINNAGVMYPPKQTTVDGFELQFGTNHLGPFALTGLLIDHLLPVEGSRVVAVASVAHRIRAKIHFEDLQWERRYNRVEAYGQSKLANLLFAYELQRRLAAAGKPTISVAAHPGLSNTELMRHIPGTGLPGYHQIASLFSNSPLMGALATLRAATDPGVKGGQYYGPDGFREVRGHPELVKSSSQSRDPELQRRLWAVSEELTGVSYPV
>NC_018289.1|WP_014876895.1|946192_947380_-|molybdopterin-molybdotransferase-MoeA
MRTVEEHQRIVAGLIKARDPQCVPIADALGLVLASDVVAPLSLPGFDNSAMDGYAVVAEDIACATADTPVLLPVAEDIPAGRTDALTLKAGTAHRIMTGAPVPAGATAVIPVEATDGATDTVTIRAAARPGQHIRRAGEDVTAGTTVLHAGQMVTPAALGLAAALGLSELTVIPPQRVMVMSTGTELVKPGTPLQPGQIYESNAVMLSAAVRDAGAQVISSPMSHDDVDNFRAVLAEHARDIDLIITTGGVSAGAYEVVKDALAKQVDFVKVAMQPGMPQGSGVVGTTPIITLPGNPVSALVSFEVFVRAPLRAAMGHPEPERPKLTATLTEPLTSPAGKRQFRRGVLTGDTVTSYGPPASHHLRWLASANCLLEIGEDVTEVPAGTSVQVWDLS
>NC_018289.1|WP_011727246.1|945458_946157_-|phosphatidylserine-decarboxylase
MARRPDLQSGPERLAALVRSSIPPMHSAGLPFVGASLAVALLGRKRRWMRRAGLISAGANAAFFRHPPRVPPTRPGVVVAPADGLICLLGEATPPAELGLPDIPMQRVSIFLSVLDAHVQRAPIGGEVVAVRHRPGRFHSAELEAASEDNERNSVVIRTPEGLHIIAVQIAGLIARRIVCDVHVGDKLSIGDTYGLIRYGSRLDTYFPADARVLVSHGQRTLAGETVLAELA
>NC_018289.1|WP_003892285.1|944601_945462_-|CDP-diacylglycerol--serine-O-phosphatidyltransferase
MIKARIKRPSFTVRMLPSALTVAAICLGLSAVKMALDNRPTEAMAFLAAAAILDALDGRVARMLKATSKMGEEIDSLADAVNFGVAPAFIVYGTLLSHSRVGWIVVLLYAVCIVLRLARFNALLDVDQPAYEKEYFVGMPAPAGAIGAIGPLAAKMQWPGEWWNSVTAEWVVIIWMIGVSLLVVSRIPMRKIHTFSVSPNMAAPLLVLVAIGVAASVFYGYIVIMVIIVAYVIHIPFAVRTKHWVASHPESWDVKPKQRRAARRAIRRAQPHRRSMARLGLRKPGR
>NC_018289.1|WP_011727245.1|942362_944600_-|AAA-family-ATPase
MSQGFDDEFGGADQYDTPLSHLRLTARLNTSALDSRRGVVRLHPEVLAALGIREWDAVALTGTRTTAAVAGVAGPGVPAGTALLDDVTLSNAGVRENAAVLVSPVTVYGARSVTVSGSRLATQSISPATLRMALLGKVMTVGDTVSLLPRDLGPGTSTSAATSALASSVGITWTSELLTVTAVDPPGTVSVQPNSVVSWGTGTPEDPAPPPTGRHTVSPQRSEQPVSFDDVKVTHPQAVKLDEWLRLSLDEPELLKTLGATPHLGVLVSGPAGVGKATMVRAVCASRRVVELDGPEVGALQVDERLRSVTSAVAAVTESGGVLFIADVDALLPAGNEMRPPEPVATLILAELRKAVATPGVAFIATSAVPENVDARLRAPEVCDRELGLSLPDATARRSLLEMLLRGVPSEDLDLGDIADHTPGFVVADLAAVVREGALRAAARASSSDDDPVLRHADLEGALTVIRPLSRSASEEVSVGSVTLDDVGDMVETKRALTEAVLWPLQHPDTFSRLGIDPPRGVLLYGPPGCGKTFVVRALASSGRLSVHAVKGSELMDKWVGSSEKAVRELFARARDSAPSLVFLDEIDALAPRRGQNFDSGVTDKVVASLLTELDGIEPLRDVVVLGATNRPDLIDPALLRPGRLERLVFVEPPDAAARRDILRTAGKSIPLADDVDLDSLADDLDGYSAADCVALLRESAMTAMRRSIDAADVTAADVAKARETVRPSLDPAQVESLREFAEKR
>NC_018289.1|WP_011727244.1|941352_942366_+|SRPBCC-family-protein
MAPPRKHETDAILDAARALVLTEGPRAAGVAAIAKASGAPVGTLYHRFGNRDGILKATWLRGIERFQRRAMAADGATPVDVAVAMAGAVLQFARDEPEDARLLLSIRRADLLDGGPDADFDATLADMNAPVFERLHELARGIFGRDDDRAMDAVMRAVADLPYATVRRHIDDGKWPVWLSEDLATSVRRLLSVDKIVSASREIAAPSDVIFELIADPAQQPRWDGNENLLRMASGGRVRGVGEVFTMEIKQGGFRDNHVIEFEEGRRIAWRPAVAGEQPLGHLWRWELQPAGEGRTLVTHTYDWTQLTDEKRFPKASATTADKLQESVDRLAAIVEG
>NC_018289.1|WP_011727254.1|957934_960100_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit
MTAPQATPALAGRAVPRVDGRLKVTGQARYAADAEVPDALFAVLVGATVARGAVDAVHTDAARRAPEVVDVITDFDGLTLKYDPQQVCAFGQAVAVVVATTLEAATHAASLVAVRYSTQPQLTDMDAPDASDQNPTPTRDYSRGDADAALRGSAVVTDLRCSMERNNHNPMEINAVVARWEGDRLTVWDKVQSVSGARQQYADALGVPAENVRVISPFVGGAFGNAGQVWPHQAIAAHVARRVGRPVKLMLTRRHLYAVTGYRPRNRQRLAIGADRSGRITAIVHEGAVEVSRYSPYVDNVTGAASYMYQAPNMRSALRTVELDVHPGNQMRGPGHLSGNFALESAMDDLAHRLAMDPIELRVRNEPTRDQTDNLPFSSRRLTECLRSGATAFGWSRRNPVPRSVREGRQLIGLGVSAASFVTLVSPCAASARVRNDGTVEILCGASDIGPGTYTAMSQVGADALGVALHRVRFQLGDSALPVAPAQTGSRLMASAGSSIHNVGMMLRDRFVRMAVTDPGSPLHGLAPADVEVADGRMAARGEPARGERYEELLRRRRLDELSAELEWTPDGPHDRFSMHSFGAVFAEVAVDEALGTVRVRRMFASYDAGRIVNPMLAHSQAIGGMVMGIGAALLEATHLDHRDGRIVNANMSDYLVPVNADVPDLDAEFLPGEDLIADPIGVKGIGELVVVGIPAAVANAVFNATGRRVTDLPITLDKLM
>NC_018289.1|WP_011727255.1|960096_961071_-|xanthine-dehydrogenase-family-protein-subunit-M
MHPFAFTKAADERSALNAAASGGRYVAGGTTLVDLMRETVERPESLVDINALPYRAIDVTRNGLRIGALVRMSELAAHPVVRTEYPVIAEALNLSASAQLRNMASIGGNLMQRPRCLYFRDVTAACNRREPGSGCPAIGGRNRTHAILGTSDQCVATHPSDLAVALTALDARVVLRDTDGENIVRLADFYRVPGTTPEQEHNMRPGQLITAVEVPATPARRSGYLKVRDRTSYEFAICSAAVALDIQGSTIRSARVAAGGVGTVPWRLPAVERALAGRPATADAIRAAADLSAEGARPLSENGFKVELLKRTVARELETIAGVQ
>NC_018289.1|WP_036462586.1|961074_961524_-|(2Fe-2S)-binding-protein
MSINGEQRVVDVDNRTSLLDMLRERVGLTGTKKGCDQGACGACTIHLNGERVVACLTLAVMHDGAEITTIEGLEDNGRLHPLQQAFIDRDALQCGYCTPGQIMSGVACIREGHANSPEEIRESMSGNICRCGAYVNIVGAVAAVARQGE
>NC_018289.1|WP_011727258.1|962228_962933_+|FadR-family-transcriptional-regulator
MRALLSREVGDAIRDYIVEHGLKPGDALPSEGELATLLDVGKTSVREALRRLEAHGVVEVRRGRGLFVGTFSFGPLIEHLPYGLQADNVPLRQLLQARRALEEGLVCEVARVITAEDLDRLDALVEQMRAHTVDGRVPAEVDQAFHQALFAPLGNPFVLQLIDVFWSIFRRASDRIVLDLRRPTAEDHAAIVDALRSGDRAAMTDAVARHFEDLQRSLDAEVNSPLAGEANEAS
>NC_018289.1|WP_011727259.1|963004_964408_+|MFS-transporter
MANSRAGEESLTPTQWKQFFAAWLGYLLDGFDFLLITLVLTEVADEFDLDLVTASTLVSAAFVSRWFGGLLLGAIGDRFGRQPAMVISILCFSIGSFLCGLSWGYWSLFVFRAIVGLGMAGEYASSVTYAMESWPKRFRNRASGALLSAYPIGVVLASQLYAVVVPHLGWRWMFFIGLVPAFVAWWMRRTLPEAQEWQNTVGSSGASRTTMQLLFSGGRRQLNIGVTVVAVAVLVLIFSRTVTGLGVWPLAVIAAACFYALARQIAGKLTPMFVMLVVTVLAAFLYSWPTQSLLPTYLKTELHFDPGQVSRVLLWAGLGYAAGSVISGVIADRLGTRRTYVLGLVISLAFVVPVFALDGAHIVWLWVLIFGLQFTSQGISGLLPKFLSDHLPVNVRASSLGFCYNIGALGGAVAPIAGASIAESIGLGNALMVLTLSFTALVAVLVGFDIPRRFAPKDLEKEEGVSV
>NC_018289.1|WP_011727260.1|964404_965337_+|dihydrodipicolinate-synthase-family-protein
MTRELTSDLAGIIPPLTTPLTADGDVDTASLERLCGFLLDAGVDGLFVCGSSGEVALLSDAQRAKAIQVAAGAASGQVPVLGGVIDTGTARVVDNALAAQKAGADAVVATPPFYVAPHADEVIRHYRLIAAAVDVPVVAYDIPSATHSPLTRSVVAQLAGEKTVAALKDSSGDLDGFRAHLAANADTGLRVFTGSETMTDVALNLGAHGAVPGLANVDPHGYVRIRQAARVGDWATAASEQERLRRIFAIVDVADRTRIGLTAGALGAFKAAQYLRGVIDTPRCADPLLPLESSEIDAVRTILEREGVLG
>NC_018289.1|WP_011727261.1|965333_966251_-|SDR-family-NAD(P)-dependent-oxidoreductase
MTKWTTARIPDQTGRVAIVTGANTGLGLETAKALAAKGAHVVLAVRNLDKGKAAVDWIARSAPTADLELQQLDLGSLASVRAAADDLKGKFDRIDLLVNNAGVMWPPRQTTADGFELQFGTNHLGHFALTGLLLDRMLTVPGSRVVTVSSQGHRILAAIHFDDLQWERRYNRVAAYGQSKLANLLFTYELQRRLTGHQTTALAAHPGASNTELARHLPGALERLVTPLAQDAALGALPTLRAATDPGALGGQYFGPDGIGETRGYPKVVASSAQSHDADLQRRLWAVSEELTGVTFPVGEALQQA
>NC_018289.1|WP_029104365.1|966355_966919_+|helix-turn-helix-transcriptional-regulator
MRADAARNRARVLEVAYEAFAQDGLAVPIDEIARRAGVGAGTVYRHFPSKEDLYRAVVAERIREIVDQGQALLADGDPGEALFDYLRLMVLQCGAADRGLVEALAGAGIDVKTMVPDAEDEYMEMLGGLLRAAQRAGTVRGDVTATDVKALLVGCQAMQAYDATAAEHLTGVVFDGLRVAPASVPSR
>NC_018289.1|WP_003892307.1|967146_968772_+|chaperonin-GroEL
MAKTIAYDEEARRGLERGLNSLADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETKEQIAATAGISAGDQSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISGYFVTDAERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIQSGKPLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVISEEVGLSLETADVSLLGKARKVVVTKDETTIVEGAGDAEAIQGRVAQIRAEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALLQSAPSLEELSLTGDEATGANIVRVALSAPLKQIALNGGLEPGVVAEKVSNLPAGHGLNAATGEYEDLLAAGVADPVKVTRSALQNAASIAALFLTTEAVVADKPEKAAAPAGDPTGGMGGMDF
>NC_018289.1|WP_011727263.1|968916_969750_+|DUF559-domain-containing-protein
MEPFIGSAAVSSGALTRRGLQRHYTALYRDVYIPRDLEVTARIRAEAAWLATRAPLAGTSAAAVLGTRWLRPELPAQIIRADRHAPPGIVAHSWTLAPGETCLVAGMDATTPARTAFDLGRLHRAGDAVPLVDALLNATGIKPADVLAVADAHPGARGVARLRVLLPLLDGGAESPQESRLRLVLVRGGLPVPQTQIEFRDLRIRVDMGWPEWKVAVEYDGVQHWSDRRQRSWDIDRIALLEEAGWVVVRVSAEMLSRPHVVVERVRAKLRAAGCPI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP032230	Streptomyces seoulensis strain KCTC 9819 plasmid unnamed	30395-30424	5	0.833
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP050095	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b1, complete sequence	235544-235573	5	0.833
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NC_008381	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL10, complete sequence	440097-440126	5	0.833
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP024288	Escherichia albertii strain 2014C-4356 plasmid unnamed6, complete sequence	15605-15634	5	0.833
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	823218-823247	5	0.833
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	MT310860	Mycobacterium phage Chris, complete genome	28930-28959	5	0.833
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	MK460246	Mycobacterium phage Nibb, complete genome	28344-28373	5	0.833
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NC_012854	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132505, complete sequence	88202-88231	5	0.833
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NC_021857	Shigella phage SfII, complete genome	8109-8138	5	0.833
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	KC814930	Shigella phage SfIV, complete genome	8065-8094	5	0.833
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NC_003444	Enterobacteria phage SfV, complete genome	7803-7832	5	0.833
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	U82619	Shigella flexneri bacteriophage V, complete genome	7803-7832	5	0.833
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP015032	Burkholderia cenocepacia strain 842 plasmid pBcn842-1, complete sequence	131819-131848	6	0.8
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP025017	Rhizobium leguminosarum strain Norway plasmid pRLN5, complete sequence	224776-224805	6	0.8
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP053443	Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eC, complete sequence	206488-206517	6	0.8
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	MH669007	Gordonia phage Marietta, complete genome	15226-15255	6	0.8
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP021032	Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence	171071-171100	6	0.8
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	13199-13228	6	0.8
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NC_028827	Streptomyces phage Lannister, complete genome	12475-12504	7	0.767
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP007796	Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence	55428-55457	7	0.767
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP012477	Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence	745572-745601	7	0.767
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP012478	Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed1, complete sequence	149382-149411	7	0.767
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP023550	Rhodobacter sp. CZR27 plasmid unnamed2, complete sequence	151168-151197	7	0.767
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	MN582099	Inoviridae sp. ctBZ32, complete genome	1092-1121	7	0.767
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	833750-833779	8	0.733
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	386173-386202	8	0.733
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NC_019307	Streptomyces sp. W75 plasmid pCQ4, complete sequence	41196-41225	8	0.733
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP032828	Sphingomonas sp. YZ-8 plasmid unnamed1, complete sequence	263301-263330	8	0.733
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	MK376955	Mycobacterium phage KiSi, complete genome	55139-55168	8	0.733
NC_018289_1	1.1\|954388\|30\|NC_018289\|CRT	954388-954417	30	NZ_CP048424	Rhizobium daejeonense strain KACC 13094 plasmid unnamed1, complete sequence	194221-194250	9	0.7
NC_018289_1	1.3\|954499\|36\|NC_018289\|CRT	954499-954534	36	KP966108	Burkholderia phage vB_BceM_AP3, complete genome	3540-3575	10	0.722

1. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP032230 (Streptomyces seoulensis strain KCTC 9819 plasmid unnamed) position: , mismatch: 5, identity: 0.833

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
ccggacccatcggcgtcaccgtcgccgccg	Protospacer
*.* .***.*************.*******

2. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP050095 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b1, complete sequence) position: , mismatch: 5, identity: 0.833

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
ccgtcgccctcggcgccaccgttgccgccg	Protospacer
*.**  ** ******.**************

3. spacer 1.1|954388|30|NC_018289|CRT matches to NC_008381 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL10, complete sequence) position: , mismatch: 5, identity: 0.833

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
ccgtcgccctcggcgccaccgttgccgccg	Protospacer
*.**  ** ******.**************

4. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP024288 (Escherichia albertii strain 2014C-4356 plasmid unnamed6, complete sequence) position: , mismatch: 5, identity: 0.833

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
cggtcaccgtcagcgtaaccgttgccgccg	Protospacer
* **  *****.**** *************

5. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 5, identity: 0.833

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
cggtttccgtcgccgtcaccgtcgccgccg	Protospacer
* ** .****** *********.*******

6. spacer 1.1|954388|30|NC_018289|CRT matches to MT310860 (Mycobacterium phage Chris, complete genome) position: , mismatch: 5, identity: 0.833

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
ctgtgcccgtcggcgacaccgtggtaaccg	Protospacer
*************** ****** *. .***

7. spacer 1.1|954388|30|NC_018289|CRT matches to MK460246 (Mycobacterium phage Nibb, complete genome) position: , mismatch: 5, identity: 0.833

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
ctgtgcccgtcggcgacaccgtggtcactg	Protospacer
*************** ****** *.*.*.*

8. spacer 1.1|954388|30|NC_018289|CRT matches to NC_012854 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132505, complete sequence) position: , mismatch: 5, identity: 0.833

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
ccgttgccctcggcgccaccgttgccgccg	Protospacer
*.**  ** ******.**************

9. spacer 1.1|954388|30|NC_018289|CRT matches to NC_021857 (Shigella phage SfII, complete genome) position: , mismatch: 5, identity: 0.833

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
cggtcaccgtcagcgtaaccgttgccgccg	Protospacer
* **  *****.**** *************

10. spacer 1.1|954388|30|NC_018289|CRT matches to KC814930 (Shigella phage SfIV, complete genome) position: , mismatch: 5, identity: 0.833

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
cggtcaccgtcagcgtaaccgttgccgccg	Protospacer
* **  *****.**** *************

11. spacer 1.1|954388|30|NC_018289|CRT matches to NC_003444 (Enterobacteria phage SfV, complete genome) position: , mismatch: 5, identity: 0.833

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
cggtcaccgtcagcgtaaccgttgccgccg	Protospacer
* **  *****.**** *************

12. spacer 1.1|954388|30|NC_018289|CRT matches to U82619 (Shigella flexneri bacteriophage V, complete genome) position: , mismatch: 5, identity: 0.833

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
cggtcaccgtcagcgtaaccgttgccgccg	Protospacer
* **  *****.**** *************

13. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP015032 (Burkholderia cenocepacia strain 842 plasmid pBcn842-1, complete sequence) position: , mismatch: 6, identity: 0.8

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
atatgccggtcgacgtcaccgttgccgcga	Protospacer
 *.**** ****.*************** .

14. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP025017 (Rhizobium leguminosarum strain Norway plasmid pRLN5, complete sequence) position: , mismatch: 6, identity: 0.8

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
ccgcagccctcggcgccaccgttgccgccg	Protospacer
*.*.. ** ******.**************

15. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP053443 (Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eC, complete sequence) position: , mismatch: 6, identity: 0.8

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
ccgcagccctcggcgccaccgttgccgccg	Protospacer
*.*.. ** ******.**************

16. spacer 1.1|954388|30|NC_018289|CRT matches to MH669007 (Gordonia phage Marietta, complete genome) position: , mismatch: 6, identity: 0.8

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
ccgccgccgttgccgtcaccgttgccgccg	Protospacer
*.*.  ****.* *****************

17. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP021032 (Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence) position: , mismatch: 6, identity: 0.8

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
ctatcgcgctcggcgccaccgttgccgccg	Protospacer
**.*  *  ******.**************

18. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 6, identity: 0.8

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
atctggacggcggcgtcaccgtcgccgccg	Protospacer
 * **  ** ************.*******

19. spacer 1.1|954388|30|NC_018289|CRT matches to NC_028827 (Streptomyces phage Lannister, complete genome) position: , mismatch: 7, identity: 0.767

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
cagtcggcgtcggcgtcaccgttgctgcac	Protospacer
* **   ******************.**

20. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP007796 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence) position: , mismatch: 7, identity: 0.767

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
cgccgggcgtcgccgtcaccgttgccgtcg	Protospacer
*  .*  ***** **************.**

21. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP012477 (Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
ccgcccgcggcggcgtcaccgttgccgcgc	Protospacer
*.*. * ** ******************

22. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP012478 (Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
ccgcccgcggcggcgtcaccgttgccgcgc	Protospacer
*.*. * ** ******************

23. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP023550 (Rhodobacter sp. CZR27 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
ttgccgccgtcgccgtcaccgtcgccgcca	Protospacer
.**.  ****** *********.******.

24. spacer 1.1|954388|30|NC_018289|CRT matches to MN582099 (Inoviridae sp. ctBZ32, complete genome) position: , mismatch: 7, identity: 0.767

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
tcgtcgccgtcgccgtcaccgttgccacca	Protospacer
..**  ****** *************.**.

25. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 8, identity: 0.733

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
agctgtccgtcggcgtcaccgttgacgtgt	Protospacer
   **.****************** **.

26. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.733

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
cgaccgccgtcggcgtccccgtcgccgcca	Protospacer
* ..  *********** ****.******.

27. spacer 1.1|954388|30|NC_018289|CRT matches to NC_019307 (Streptomyces sp. W75 plasmid pCQ4, complete sequence) position: , mismatch: 8, identity: 0.733

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
tcgacaccgtcggcgtcaccgtgcccgcca	Protospacer
..*   ****************  *****.

28. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP032828 (Sphingomonas sp. YZ-8 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
ctgtgcccgtcgccgtcaccgcgcttgggg	Protospacer
************ ********.  ..*  *

29. spacer 1.1|954388|30|NC_018289|CRT matches to MK376955 (Mycobacterium phage KiSi, complete genome) position: , mismatch: 8, identity: 0.733

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
cacagcccctcggcgtcacccttgccggtc	Protospacer
*   **** *********** ****** .

30. spacer 1.1|954388|30|NC_018289|CRT matches to NZ_CP048424 (Rhizobium daejeonense strain KACC 13094 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

ctgtgcccgtcggcgtcaccgttgccgccg	CRISPR spacer
tggattatctcggcgtcaccgtggccgccg	Protospacer
. *  . . ************* *******

31. spacer 1.3|954499|36|NC_018289|CRT matches to KP966108 (Burkholderia phage vB_BceM_AP3, complete genome) position: , mismatch: 10, identity: 0.722

ttgccgccggcacccgtgtgcgatgggtcgacgtac	CRISPR spacer
ccggcgctgtcacccgtgtgcgatgggtcgtagcct	Protospacer
..* ***.* ********************  *. .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

433839 : 442298

Shahe_endorna-like_virus(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726901.1\|433839_434706_-	glucose-1-phosphate thymidylyltransferase RfbA	A0A291LA53	Escherichia_phage	7.3e-90	58.0
WP_014876757.1\|435212_436481_+	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	4.3e-06	37.3
WP_014876758.1\|436598_437672_+	SDR family NAD(P)-dependent oxidoreductase	A0A0E3IB24	Synechococcus_phage	2.3e-21	26.9
WP_011726904.1\|437920_438655_+	class I SAM-dependent methyltransferase	A0A0B4ZZS0	Mycobacterium_phage	1.8e-12	32.3
WP_014876760.1\|438906_439707_+	class I SAM-dependent methyltransferase	A0A2R8FDY2	Brazilian_cedratvirus	1.4e-58	53.3
WP_011726906.1\|439740_441009_+	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	7.3e-06	37.1
WP_042510611.1\|441185_442298_+	acyltransferase	A9YX16	Burkholderia_phage	4.9e-22	29.5

DBSCAN-SWA_2

2215130 : 2222697

Mycobacterium_phage(50.0%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011728185.1\|2215130_2216339_-	Fic family protein	D7RWK9	Brochothrix_phage	1.3e-07	25.0
WP_003893512.1\|2216397_2216649_+	hypothetical protein	A0A0A7S2B5	Mycobacterium_phage	9.0e-33	89.6
WP_011728186.1\|2216663_2217362_+	hypothetical protein	A0A0A7RXU2	Mycobacterium_phage	3.6e-124	93.5
WP_011728187.1\|2217372_2217813_-	SecB-like chaperone SecBL	A0A160DCY1	Gordonia_phage	6.4e-18	38.8
WP_003893515.1\|2217809_2218406_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_029104517.1\|2218738_2219038_+	hypothetical protein	A0A0A7RVJ2	Mycobacterium_phage	1.2e-44	89.9
WP_011728188.1\|2219052_2222697_+\|tail	phage tail tape measure protein	Q854Y3	Mycobacterium_virus	0.0e+00	92.5

DBSCAN-SWA_3

4186314 : 4241071

Shigella_phage(12.5%)

integrase,transposase

attL 4180420:4180436|attR 4244158:4244174

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4180420:4180436	attL	NA	NA	NA	NA
WP_085976167.1\|4186314_4187480_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.2e-32	36.4
WP_011729554.1\|4187558_4188245_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_011729555.1\|4188254_4189694_-	Re/Si-specific NAD(P)(+) transhydrogenase subunit beta	NA	NA	NA	NA
WP_014877938.1\|4189712_4191254_-	Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha	NA	NA	NA	NA
WP_011729557.1\|4191391_4192234_-	3-hydroxyacyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_011729558.1\|4192286_4193417_-	CoA transferase	NA	NA	NA	NA
WP_011729559.1\|4193413_4195081_-	cyclohexanecarboxylate-CoA ligase	Q75ZG1	Hepacivirus	1.1e-28	25.0
WP_011729560.1\|4195083_4196139_-	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_011729561.1\|4196135_4196912_-	naphthoate synthase	NA	NA	NA	NA
WP_011729562.1\|4196913_4197795_-	3-hydroxybutyryl-CoA dehydrogenase	NA	NA	NA	NA
WP_011729563.1\|4197804_4198695_-	3-hydroxyacyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_011729564.1\|4198714_4199479_-	3-oxoacyl-ACP reductase FabG	NA	NA	NA	NA
WP_011729565.1\|4199475_4200699_-	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_011729566.1\|4200695_4201484_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_042510654.1\|4201480_4202659_-	CoA transferase	NA	NA	NA	NA
WP_011729568.1\|4202969_4203710_-	FadR family transcriptional regulator	NA	NA	NA	NA
WP_011729569.1\|4203858_4205220_-	MHS family MFS transporter	Q6JIH2	Burkholderia_virus	8.0e-43	31.3
WP_011729570.1\|4205581_4206481_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_014877941.1\|4206477_4207770_+	MmgE/PrpD family protein	NA	NA	NA	NA
WP_011729572.1\|4207821_4208604_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_014877942.1\|4208768_4209527_+	isochorismatase family protein	NA	NA	NA	NA
WP_011729574.1\|4209749_4211153_-\|transposase	IS1380-like element ISMsm12 family transposase	NA	NA	NA	NA
WP_011729575.1\|4211188_4212025_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011729576.1\|4212123_4212714_+	TetR family transcriptional regulator C-terminal domain-containing protein	NA	NA	NA	NA
WP_011729578.1\|4212869_4213721_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_011729580.1\|4217179_4217731_-	TIGR00730 family Rossman fold protein	NA	NA	NA	NA
WP_011729581.1\|4217768_4218353_-	NAD(P)H-binding protein	NA	NA	NA	NA
WP_011729582.1\|4218352_4218571_-	hypothetical protein	NA	NA	NA	NA
WP_014877947.1\|4218952_4219930_+	aliphatic nitrilase	NA	NA	NA	NA
WP_080590936.1\|4220310_4221294_+	MFS transporter	NA	NA	NA	NA
WP_011729584.1\|4221319_4222753_+	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_011729585.1\|4222948_4223836_+	LLM class F420-dependent oxidoreductase	NA	NA	NA	NA
WP_011729586.1\|4224006_4224633_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_011729587.1\|4224768_4225062_+	DUF1330 domain-containing protein	NA	NA	NA	NA
WP_011729588.1\|4225105_4226044_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011729589.1\|4226348_4226912_-	cupin domain-containing protein	NA	NA	NA	NA
WP_011729590.1\|4227274_4228252_+	quinone oxidoreductase	NA	NA	NA	NA
WP_011729591.1\|4228306_4229581_+	MFS transporter	NA	NA	NA	NA
WP_162139608.1\|4229700_4230528_-	alpha/beta hydrolase fold domain-containing protein	M1PGN2	Moumouvirus	4.6e-25	28.5
WP_011729593.1\|4230802_4231738_+	acetaldehyde dehydrogenase (acetylating)	G9E526	Ostreococcus_lucimarinus_virus	1.8e-33	31.8
WP_011729594.1\|4231734_4232775_+	4-hydroxy-2-oxovalerate aldolase	E5EQ69	Micromonas_sp._RCC1109_virus	1.2e-43	32.8
WP_011729595.1\|4232783_4233035_-	ferredoxin	NA	NA	NA	NA
WP_011729596.1\|4233031_4233985_-	oxidoreductase	NA	NA	NA	NA
WP_011729597.1\|4233987_4234446_-	cytochrome P450	NA	NA	NA	NA
WP_014877954.1\|4235638_4236748_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_011729600.1\|4236744_4238970_+\|integrase	tyrosine-type recombinase/integrase	A0A1P8DJJ6	Virus_Rctr41k	1.2e-08	26.0
WP_011729601.1\|4238959_4239388_+\|transposase	transposase	NA	NA	NA	NA
WP_011727856.1\|4239751_4241071_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.8e-250	100.0
4244158:4244174	attR	NA	NA	NA	NA

DBSCAN-SWA_4

6168055 : 6236001

Mycobacterium_phage(33.33%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003897506.1\|6168055_6170368_-\|protease	ATP-dependent zinc metalloprotease FtsH	E5EQU5	Bathycoccus_sp._RCC1105_virus	7.1e-108	44.9
WP_011731041.1\|6170564_6171536_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_014878559.1\|6171532_6172723_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_011731043.1\|6172722_6173739_+	zinc-binding dehydrogenase	NA	NA	NA	NA
WP_003897510.1\|6173760_6174492_+	SIMPL domain-containing protein	NA	NA	NA	NA
WP_003897511.1\|6174496_6175051_-	hypoxanthine phosphoribosyltransferase	A0A1V0SEQ1	Hokovirus	3.1e-09	29.1
WP_011731045.1\|6175128_6176097_-\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_175048376.1\|6176075_6177158_-\|protease	zinc-dependent metalloprotease	NA	NA	NA	NA
WP_029104179.1\|6177145_6178528_-	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase	NA	NA	NA	NA
WP_011731048.1\|6178671_6179160_+	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	5.1e-32	45.3
WP_003897516.1\|6179220_6179751_+	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase	NA	NA	NA	NA
WP_011731049.1\|6179726_6180731_-	2-hydroxyacid dehydrogenase	M1I539	Acanthocystis_turfacea_Chlorella_virus	3.2e-12	26.1
WP_011731050.1\|6180736_6182086_-	glucarate dehydratase	NA	NA	NA	NA
WP_011731051.1\|6182111_6182912_-	IclR family transcriptional regulator	NA	NA	NA	NA
WP_011731052.1\|6182913_6183636_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_011731053.1\|6183632_6184631_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.5e-17	30.0
WP_011731054.1\|6184623_6185655_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-13	31.1
WP_003897523.1\|6185651_6186638_-	ABC transporter permease	NA	NA	NA	NA
WP_011731055.1\|6186646_6187576_-	ABC transporter permease	NA	NA	NA	NA
WP_011731056.1\|6187603_6189166_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011731057.1\|6189459_6190473_+	2-hydroxyacid dehydrogenase	A0A1B1IVB5	uncultured_Mediterranean_phage	6.9e-15	31.9
WP_003897528.1\|6190466_6191396_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011731058.1\|6191652_6192012_+	STAS domain-containing protein	NA	NA	NA	NA
WP_011731059.1\|6192045_6192492_+	anti-sigma factor	NA	NA	NA	NA
WP_011731060.1\|6192477_6192924_-	response regulator	NA	NA	NA	NA
WP_011731061.1\|6192920_6194498_-	CHASE3 domain-containing protein	A0A1V0SGX0	Hokovirus	1.1e-16	27.8
WP_011731062.1\|6194494_6195703_-	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_011731063.1\|6195933_6197205_-	glucarate dehydratase	NA	NA	NA	NA
WP_011731064.1\|6197215_6198139_-	5-dehydro-4-deoxyglucarate dehydratase	NA	NA	NA	NA
WP_011731065.1\|6198169_6199768_-	aldehyde dehydrogenase (NADP(+))	NA	NA	NA	NA
WP_011731066.1\|6199910_6200315_-	hypothetical protein	NA	NA	NA	NA
WP_003897538.1\|6200416_6201385_-	TerC family protein	A0A291LBC5	Escherichia_phage	4.4e-35	33.7
WP_011731067.1\|6201613_6205549_+	non-ribosomal peptide synthetase	A0A2K9L3I8	Tupanvirus	3.3e-36	24.1
WP_011731068.1\|6205545_6206883_+	M1 family metallopeptidase	NA	NA	NA	NA
WP_011731069.1\|6206879_6208160_+	membrane protein	NA	NA	NA	NA
WP_011731070.1\|6208149_6208743_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_011731071.1\|6208744_6210526_-	amidohydrolase family protein	NA	NA	NA	NA
WP_029104180.1\|6210587_6211529_-	UDP-glucose 4-epimerase	L7RCI0	Acanthamoeba_polyphaga_moumouvirus	3.9e-36	34.6
WP_011731073.1\|6211585_6213349_+	hypothetical protein	NA	NA	NA	NA
WP_011731074.1\|6213350_6214802_-	PE-PPE domain-containing protein	A0A222ZKN7	Mycobacterium_phage	7.7e-76	53.3
WP_011731075.1\|6215113_6215830_+	hypothetical protein	NA	NA	NA	NA
WP_011726768.1\|6215910_6217317_+\|transposase	IS1380-like element ISMsm3 family transposase	A0A222ZN33	Mycobacterium_phage	5.1e-85	43.9
WP_162139567.1\|6217410_6218583_+	hypothetical protein	NA	NA	NA	NA
WP_011726739.1\|6218669_6219992_+\|transposase	ISL3-like element IS1096 family transposase	A0A2H4PDF8	Mycobacterium_phage	1.1e-254	100.0
WP_011726740.1\|6219999_6220701_-	plasmid pRiA4b ORF-3 family protein	A0A2H4PDG5	Mycobacterium_phage	2.0e-138	99.6
WP_014878573.1\|6221275_6221641_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_011731077.1\|6221637_6222513_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_011731078.1\|6222735_6223944_-	DNA polymerase III subunit delta'	NA	NA	NA	NA
WP_011731079.1\|6224025_6225717_+	adenylate/guanylate cyclase domain-containing protein	A0A1B1IWY2	uncultured_Mediterranean_phage	2.5e-17	31.7
WP_011726739.1\|6225774_6227097_+\|transposase	ISL3-like element IS1096 family transposase	A0A2H4PDF8	Mycobacterium_phage	1.1e-254	100.0
WP_011726740.1\|6227104_6227806_-	plasmid pRiA4b ORF-3 family protein	A0A2H4PDG5	Mycobacterium_phage	2.0e-138	99.6
WP_011731080.1\|6227968_6230779_-	type I DNA topoisomerase	A0A2K9L5F8	Tupanvirus	1.4e-97	31.3
WP_003897557.1\|6230882_6231476_-	hypothetical protein	NA	NA	NA	NA
WP_011562175.1\|6231571_6231775_-	cold-shock protein	A0A1X9IGI9	Lactococcus_phage	1.5e-14	56.2
WP_003897559.1\|6232076_6234407_+	DEAD/DEAH box helicase	NA	NA	NA	NA
WP_011726739.1\|6234678_6236001_+\|transposase	ISL3-like element IS1096 family transposase	A0A2H4PDF8	Mycobacterium_phage	1.1e-254	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage