CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017093	Actinoplanes missouriensis 431, complete genome	27 crisprs	cas3,DEDDh,WYL,csa3,DinG	6	23	2	0

1. NC_017093

CRISPR-Cas detection and classification

Crispr_ID: NC_017093_1

• CRISPR_ID: NC_017093_1
• CRISPR_location: 191059-191135
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_1

Consensus_repeat	Method
GAGCTGGAGGAGACGAACCGCGG	CRISPRCasFinder

spacers of NC_017093_1

>1.1|191082|31|NC_017093|CRISPRCasFinder
CGTGATGGCCCTCTACCACCAGCTCTCCGAG

CRISPR arrays and Neighbor proteins around NC_017093_1

CRISPR arrays

The CRISPR arrays of NC_017093_1

>merge|NC_017093|1|191059-191135|CRISPRCasFinder
GAGCTGGAGGAGACGAACCGCGGCGTGATGGCCCTCTACCACCAGCTCTCCGAGGAGCTGGAGGAGACGAACCGCGG

>NC_017093|1|1|191059-191135|CRISPRCasFinder
GAGCTGGAGGAGACGAACCGCGG	CGTGATGGCCCTCTACCACCAGCTCTCCGAG
GAGCTGGAGGAGACGAACCGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_014440287.1|187817_188675_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132912
NC_017093.1|WP_014440295.1|194707_196252_+|FtsX-like-permease-family-protein	unknown	unknown	unknown
NC_017093.1|WP_014440298.1|199880_200495_-|dihydrofolate-reductase-family-protein	unknown	unknown	gnl|CDD|223340
NC_017093.1|WP_041830387.1|186719_187169_-|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl|CDD|376605
NC_017093.1|WP_014440299.1|200556_201114_-|dihydrofolate-reductase	unknown	unknown	gnl|CDD|223340
NC_017093.1|WP_014440301.1|203288_207692_+|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|237951
NC_017093.1|WP_014440283.1|185446_186361_+|zf-HC2-domain-containing-protein	unknown	unknown	gnl|CDD|227947
NC_017093.1|WP_014440282.1|184589_185219_+|CGNR-zinc-finger-domain-containing-protein	unknown	unknown	gnl|CDD|378696
NC_017093.1|WP_157434701.1|198585_199713_+|FAD-binding-protein	unknown	unknown	gnl|CDD|223354
NC_017093.1|WP_014440289.1|189092_189497_+|ATP-binding-protein	unknown	unknown	gnl|CDD|340411
NC_017093.1|WP_014440294.1|194024_194711_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NC_017093.1|WP_014440292.1|191870_193424_+|fused-response-regulator/phosphatase	unknown	unknown	gnl|CDD|369272
NC_017093.1|WP_014440293.1|193488_194028_+|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NC_017093.1|WP_014440284.1|186422_186656_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014440288.1|188676_189096_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132912
NC_017093.1|WP_014440290.1|189493_190525_+|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|340411
NC_017093.1|WP_157434702.1|201149_203228_-|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|225118
NC_017093.1|WP_157435223.1|183653_184382_-|peptidoglycan-binding-protein	unknown	unknown	gnl|CDD|341130
NC_017093.1|WP_014440296.1|196384_198448_-|S9-family-peptidase	unknown	unknown	gnl|CDD|224684
NC_017093.1|WP_014440286.1|187289_187643_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_014440287.1|187817_188675_+|STAS-domain-containing-protein	gnl|CDD|132912	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation. The STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain of proteins related to RsbS and RsbR which are part of the "stressosome" complex that plays an important role in the regulation of the bacterial stress activated alternative sigma factor sigma-B. During stress conditions RsbS and RsbR are phosphorylated which leads to the release of RsbT, an activator of of the RsbU phosphatase, which in turn activates RsbV which leads to the release and activation of sigma factor B. RsbS is a single domain protein (STAS domain), while RsbR-like proteins have a well-conserved C-terminal STATS domain and a variable N-terminal domain. The STAS domain is also found in the C- terminal region of sulphate transporters and anti-anti-sigma factors.	9.41826e-44
NC_017093.1|WP_014440298.1|199880_200495_-|dihydrofolate-reductase-family-protein	gnl|CDD|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	4.11615e-16
NC_017093.1|WP_041830387.1|186719_187169_-|large-conductance-mechanosensitive-channel-protein-MscL	gnl|CDD|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	4.70641e-52
NC_017093.1|WP_014440299.1|200556_201114_-|dihydrofolate-reductase	gnl|CDD|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	2.28061e-19
NC_017093.1|WP_014440301.1|203288_207692_+|HAMP-domain-containing-protein	gnl|CDD|237951	PRK15347, PRK15347, two component system sensor kinase.	9.13998e-70
NC_017093.1|WP_014440283.1|185446_186361_+|zf-HC2-domain-containing-protein	gnl|CDD|227947	COG5660, COG5660, Predicted integral membrane protein [Function unknown].	7.9803e-19
NC_017093.1|WP_014440282.1|184589_185219_+|CGNR-zinc-finger-domain-containing-protein	gnl|CDD|378696	pfam11706, zf-CGNR, CGNR zinc finger. This family consists of a C-terminal zinc finger domain. It seems likely to be DNA-binding given the conservation of many positively charged residues. The domain is named after a highly conserved motif found in many members of the family.	3.73558e-13
NC_017093.1|WP_157434701.1|198585_199713_+|FAD-binding-protein	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.64263e-19
NC_017093.1|WP_014440294.1|194024_194711_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	7.44698e-94
NC_017093.1|WP_014440292.1|191870_193424_+|fused-response-regulator/phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	5.81451e-44
NC_017093.1|WP_014440293.1|193488_194028_+|PadR-family-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	5.69373e-18
NC_017093.1|WP_014440289.1|189092_189497_+|ATP-binding-protein	gnl|CDD|340411	cd16934, HATPase_RsbT-like, Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine/threonine-protein kinase RsbT, and related domains. This family includes the histidine kinase-like ATPase (HATPase) domain of Bacillus subtilis serine/threonine-protein kinase RsbT, a component of the stressosome signaling complex of Bacillus subtilis. The stressosome is formed from multiple copies of three proteins, a sensor protein RsbR, a scaffold protein RsbS, and RsbT, and responds to environmental changes by initiating a protein partner switching cascade. Stress perception increases the phosphorylation of RsbR and RsbS, by RsbT. Subsequent dissociation of RsbT from the stressosome activates the sigma-B cascade, leading to the release of the alternative sigma factor, sigma-B.	2.08084e-39
NC_017093.1|WP_014440288.1|188676_189096_+|STAS-domain-containing-protein	gnl|CDD|132912	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation. The STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain of proteins related to RsbS and RsbR which are part of the "stressosome" complex that plays an important role in the regulation of the bacterial stress activated alternative sigma factor sigma-B. During stress conditions RsbS and RsbR are phosphorylated which leads to the release of RsbT, an activator of of the RsbU phosphatase, which in turn activates RsbV which leads to the release and activation of sigma factor B. RsbS is a single domain protein (STAS domain), while RsbR-like proteins have a well-conserved C-terminal STATS domain and a variable N-terminal domain. The STAS domain is also found in the C- terminal region of sulphate transporters and anti-anti-sigma factors.	3.91189e-31
NC_017093.1|WP_014440290.1|189493_190525_+|SpoIIE-family-protein-phosphatase	gnl|CDD|340411	cd16934, HATPase_RsbT-like, Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine/threonine-protein kinase RsbT, and related domains. This family includes the histidine kinase-like ATPase (HATPase) domain of Bacillus subtilis serine/threonine-protein kinase RsbT, a component of the stressosome signaling complex of Bacillus subtilis. The stressosome is formed from multiple copies of three proteins, a sensor protein RsbR, a scaffold protein RsbS, and RsbT, and responds to environmental changes by initiating a protein partner switching cascade. Stress perception increases the phosphorylation of RsbR and RsbS, by RsbT. Subsequent dissociation of RsbT from the stressosome activates the sigma-B cascade, leading to the release of the alternative sigma factor, sigma-B.	1.88292e-25
NC_017093.1|WP_157434702.1|201149_203228_-|SpoIIE-family-protein-phosphatase	gnl|CDD|225118	COG2208, RsbU, Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription].	1.14274e-36
NC_017093.1|WP_157435223.1|183653_184382_-|peptidoglycan-binding-protein	gnl|CDD|341130	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD. Members of the YkuD-like family of proteins are found in a range of bacteria. The best studied member Bacillus YkuD has been shown to act as an L,D-transpeptidase that gives rise to an alternative pathway for peptidoglycan cross-linking. Another member Helicobacter pylori Csd6 functions as an L,D-carboxypeptidase and regulates helical cell shape and motility. The conserved region contains a conserved histidine and cysteine, with the cysteine thought to be an active site residue.	8.37153e-19
NC_017093.1|WP_014440296.1|196384_198448_-|S9-family-peptidase	gnl|CDD|224684	COG1770, PtrB, Protease II [Amino acid transport and metabolism].	0
NC_017093.1|WP_014440286.1|187289_187643_-|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	6.59527e-29

Protein sequences

>NC_017093.1|WP_014440290.1|189493_190525_+|SpoIIE-family-protein-phosphatase
MSGDTVVSLPEELLGEGVWFRVEEAVTAAAVRRAAERLATDLGMPDRRVADLSIVAAEAAGNLVKHADQGLILVRAVRTAEHAGVEIIALDSGPGIADVDRAIGDGHSTAGTLGIGLGAILRQASRWDMYSQPGRGTVLAVQVWPVAPPAPGWVAGLTRPLPGETVSGDAYAVRQDGDRRQVLVCDGLGHGGLAAAASHEAVRTFLSGAFAPPAATVDALHRALNHTRGAALAVAELDTSAGLVRYAGLGNIAGTVLAPDGTRRGMISMPGIAGHQRRQVREYDYPLVPGAVVLMHTDGVVDRWNPSDYPGLLTRSPEVIAATVLRDAGTRRDDAGVLVARPS
>NC_017093.1|WP_014440289.1|189092_189497_+|ATP-binding-protein
MTEESQRLPVSTDQDVVRVRQLVRTVAVAVKLSLVDQTKLVTAASELARNTLVYGGGGEVIVSRVQSDRRPGIRIVFADQGPGIADLDLALTDGYTTGGGLGLGLSGARRLVDEFEIQTEVGKGTTITVTKWCR
>NC_017093.1|WP_014440288.1|188676_189096_+|STAS-domain-containing-protein
MERVPVLKIGDILLVSIQIDMEDQVALQLQEDLAERIVATGCHGVIIDISALDIVDSFVGRTLATIASVSRVLDAETVVVGMRPAVAITLVELGLSLPGIRTALDVELGIEMLARARQDSDPEPDFDEDEPDTAAVTTP
>NC_017093.1|WP_014440287.1|187817_188675_+|STAS-domain-containing-protein
MPLSSDEARRFADLLKEHAESLTARWAELAGAGLRGRLSGAELRRQVEDLRKGFAEALSAGSVDLTDERSAELRAQLGELSSHRARQGFTATETAVSIYAFKDAVLEVLGDGTDAGTLRDYVAFSTFVDRAALFTFDSYVKVREGLIADQAEQLLELSTPVVKLWEGVVAVPLVGTLDSARAQVVMERLLQTLVDTSSPYAIIDITGVPAVDTQVAQHILKTVVAARLMGADCIISGIRPQIAQTIVALGIEFGDIATKASLADALRYVLGKTGSRSLPAKRAER
>NC_017093.1|WP_014440286.1|187289_187643_-|STAS-domain-containing-protein
MSLTVQTEQRGDMVVVSVAGELDMATAPQLQDQISDLLEKGRTRLIFDLAEVSFCDSTGLSVFVRAKNSTDDAGGTVRLAAPQRGVLRILEVSGLVEVLHTYPTVDEAVTAEEPALD
>NC_017093.1|WP_041830387.1|186719_187169_-|large-conductance-mechanosensitive-channel-protein-MscL
MLQGFKDFIMRGNVVDLAVGVVIGAAFTTVVTSFTNAFLKPLIQLLGGGTGLTAGTFEINKVPFDYASFINALITFLLTAAVLYFLVVFPLNRLAERRRRGEEPPPKAPSEEVKLLTEIRDALLRGQGHQVSNSALDEVLGRHSQQPPR
>NC_017093.1|WP_014440284.1|186422_186656_-|hypothetical-protein
MEQRKHWWNGKWGRLARKDVYLRVSGDQWYVEQRAGGSDGVSHFFEFDGEDAALDMVRGMLNGPDEWRELSVRPPAR
>NC_017093.1|WP_014440283.1|185446_186361_+|zf-HC2-domain-containing-protein
MACERWREMLSAQLDGEDDPVMRPLVDEHLAGCAGCRDWLDRAAAVNRLTRTHAVPSVPDLTDAILAALPPSPAPAAARSADARSSDAPAVGAGSSAGRSPEAAGRSPEGVPARRRWRLPVAALLYIALALVGTVQLMLGLTQVGGGVSAAHDHAGLNATPGHLWHESAAWNVAIGAGYLFIALRRTRPTGLLPTLTAFVAMLLLLSVNDLTGGRVDVARLVGHGFVIVGYVLVVALARGVGGAARPPGARIGTGWRARFDPDSEPTVPGAEPTGPARPGLRLLPPLPPSGPLTARAPHEDRAA
>NC_017093.1|WP_014440282.1|184589_185219_+|CGNR-zinc-finger-domain-containing-protein
MSWKASARHGVREAPGGFALVQELLNTRGTMAYGADLLVSGEDAQWWVTDALGAWSRVSGLPAPTLLLSAGDLRSLRRLRVAFEQVVLAGANPERDSALPPADVQVSLVPDADGWVRVVPTGRGVRWFASALWAEALQAQQAGVWPRLKLCHNNACRAAFFDTSRNNSGVWHDVSTCGNTANLRAFRERRRLLGNSGGQRAGVPGPERR
>NC_017093.1|WP_157435223.1|183653_184382_-|peptidoglycan-binding-protein
MATGPAASPVPSQASSAPTSSAGPASPAAPTSSAAATPASPEGPPKKLRPGAEGAEVLALQNRLTALGYWNGKPDGKFGSTTQQAVFALQKTAKLGRDGVVGPRTHQALERGVRPAAKSTSGKFVEIDLKRQLLLLVQDGRVEQIFNTSTGSNEYYEQDGETYLADTPRGRFRVSRQIDGWRNAPLGLLWRPKYFNGGIAVHGAPSVPAHPASHGCARVSIAAMNWLWSHDEIPVKTRVWVY
>NC_017093.1|WP_014440292.1|191870_193424_+|fused-response-regulator/phosphatase
MSAGVQSKVPATVMVVDDSATKRYLLVSWLTRAGFAVLEAETGGEALDKLVDAEADLVVLDVKLPDMSGFEVCERIKTDQRYGVLPVIHVSAHAVDVNDRTQGLNRGADAYLVEPIEPDELIATAQAVLRYYRARRRAEQLAERMVRLAETTLAINSAGTLTDLLAAAAEGAQDIFGGPVMVVADTSEGESLAAAGQPARVRPWTVPEHAVAVGSLVRTDEPADWDMVDWPAGDTVAVAAARLRADRPPVYVAAPASTQNSGFPVLRQLSQAVAAAVEAQRSFDEEHRIAVTLQRSLLQSELPKVPGVELAVRYEPAGAQTEVGGDFYELTVLGGELLVAIGDVAGHSLHAATVMAELRHAVRAYAVEGHPPGEVLELVNRFMRTVLPDDSATLCLLTLDPVTGRIRMASAGHLPPLVHTDGEARFLSPRGALLGIAAPRRAELEFTLPPGGTLVLYTDGLIERRDTDIDVGLRALSAIAGEVEPDLDAFCSRLLTLLAGPGEQADDIAVVALRRNA
>NC_017093.1|WP_014440293.1|193488_194028_+|PadR-family-transcriptional-regulator
MSTAHVLLGLLAGGPRHGYDLKRAHDERLPQAKPLAYGQVYATLGRLERDGLVEQSGQEQEGGPERTSYALTKLGRERLDTWLTEVEPPAPYVTSTLFNKVVVALLAADADRARQYLTAQRAVHMARMRELTRTRTGPGTTVGDVIAADYAIGHLDADLRWLQTTMARVAELQKEVTTP
>NC_017093.1|WP_014440294.1|194024_194711_+|ABC-transporter-ATP-binding-protein
MTAHLLTATGVQKNYGPTQALRGVDFSIAAGEIVAVTGPSGCGKSTLLHCLAGILRADAGEIRYRDQDIGLFSEAARSRLRRSDFGVLFQFGQLVPELTAAENVALPLLLAGSGRQEARKAAIGWLDRFGVADLADKRPGAMSGGQQQRCAAARALVTEPQVIFADEPTGALDQLSGEQVLGAMVQVVRDQGAAVVLVTHEATIAAYADREIVLRDGAVDPTGLGVTP
>NC_017093.1|WP_014440295.1|194707_196252_+|FtsX-like-permease-family-protein
MRLSTLVRLSLAGNRTDRLRTALTAASAALAAVALLAAAAVASIRGGDLIDDPESLRTRTPGSEHYASALLAEGGLRPGVIFTILMLALPVLALAGQCIRLGAPARDRRLAALRLSGATPRQTVLIAGAETAAASLLGSVIGLGVFAVLRATLDPRSADGRLWLPVDVVPDPLLVVGALLLVPLLAGAIGVLLMRRVVITPLGVVRRLREKGPWPWPGVLIGVGLVAFIGPEVLPDDRAAGLPEQAPLYFMAVGVLLATLGVILGVGWISYTAGRLLRRYGKGAGTLLAGARLMADPWNGSRTLGALLAAIVVGAGTLSFRTMLVTDFEASARYEEIIEGTDYSGYGSVSDLGFYLGAIRLLMVAVSIAVAVAAAGVLIAFVEGIVARRRTYAALTATGVPRRTLTSVLLWHTFVPLIPALLVALATGAALFRMTGTEITLGAPYQQCVDPNPVSWETCAKETVVPPTLVVPVPIPFADLALLGGGALAAMLLVVGVCAVVLRTSADLEELRVG
>NC_017093.1|WP_014440296.1|196384_198448_-|S9-family-peptidase
MTIEAPPTAHQSPSERTFHGDTVTDEFAWLMNKEDPATIAYLEAENAWTERATAHLDDLRKKVFQEIRSRTQETDLSVPTRKGAHWYYTRTVEGKQYGIHCRVPVRPGETDPPMDAEKPGEEVLLDGNELAEGKEFFALGTFDVSPDGNWLAYSTDFAGDERFVLKIKNLRTGEVLADEISDAFYGSAWSADGSVLFYITVDEAWRPYRVWRHVVGETTDTIIYEEPDERFWVGVDLTRSEKFIVIDAQSKITSEVRVIPADRPEAEPALIAERVQGVEYSLEHHGHRFLILHNRDAEDFALACTSVDNPGEWIELIPHEPGTRLESVDAFARHVVVSLRRDGLTGLRVMTDGSTDRYDMPFPEPIYSVGLAGNPEYDTSSVRISYTSLVTPESVFDVDLVTRAMTLRKQKPVLGGYNPADYEQFREWATAPDGTRVPISIVARKGTQRNGDNPAVIYGYGSYEHSIDPYFSIARLSLLDRGVVFAIAHVRGGGELGRRWYEHGKMLAKKNTFTDFVACAEALVRARWTSASRLVARGGSAGGLLMGAVANLAPQAFAGIVAEVPFVDPLTSILDPSLPLTVTEWEEWGNPLESPEVYAYMKSYSPYENVAKLHYPQILAVTSLNDTRVLYHEPTKWIARLRAVAPGGTYLLKTEMGAGHGGPSGRYDSWKEEAFVLSWILDVVKAV
>NC_017093.1|WP_157434701.1|198585_199713_+|FAD-binding-protein
MSDSLLDALVDICGPGFARPARTVDQAAGRRARFVAQPATATSAAAVLRLAAERGLSFRARGAGTKIDWGTPPAGLDIIVDTGRLNGMWDHRDSTAVVAAGTPVSAVQAALALKGQRLAVDPPSRGATVGGMLAVNESGPLRHRFGSPAAQTASVSFVSVAGSEETSDGEDGRPGIAEIDGVLTSAVLTVEPLPAARRWVGRTVSTPAEVDDLVSSVLAQDVSPSGIEVDLPGAGGGVLALLLEGAESEVTGSADKVAGAWGGGAVVASSAPSWWGRYPFAEGDVAVRIAVQPRHLQAVAYSLRDAAGGAVAIRGSAGVGAVHAVLPGELGVTRVREIVTALEQVLIARRGRLAVVAAAPEMAVQLPMTETRELF
>NC_017093.1|WP_014440298.1|199880_200495_-|dihydrofolate-reductase-family-protein
MAKTQYYTATSIDGFIADKSNSLDWLFEVDEGTANPFGEFFAGVGAFAMGATTYEWVLKNDNLLEEPENWHDMYGDVPCWVFTHRDLPPVPDANVFMISGDVRRVHEAMVVAAQGKNVWLAGGGNLVSQFVDHGLLDEIILGIAPAILGDGAPLLRRKLLVDDLILTGVREVGQFAYLTYAVGDVARLGRHLAAEAVTRIPSLG
>NC_017093.1|WP_014440299.1|200556_201114_-|dihydrofolate-reductase
MKTQYYTATTIDGFIADEHNSLDWLFEVDEGGENPFAEFFAGIGAFAMGSTTYEWILAHEDALEHPKKWIEPYGDTPAWIFSSRELPAIPGANLHFVRGDVAPVHAEMVTAAQGKNIWLVGGGELVARFADEGLLDEVILGVAPVSLGKGAPVLPRRITSSRFTLTGARPIGQFAYLTYDVSKPS
>NC_017093.1|WP_157434702.1|201149_203228_-|SpoIIE-family-protein-phosphatase
MRETTLCIHPPAGEDAWVPAEVGTIPTGASLDALVRRTRLPNDRRTPAAARALVRSVLEETGLVSLLNEALLLTTELSTNAVVHANTELEIEVTADAGGLTVTVTDFAPGPVEQLAVGPKNESPDIGEVAERGRGLLLVDHFASRWGTVHEGDGKGVWFRLDQRSGSGAAQIRLPQHGESPSLGALTGLLRSGNDRHTDEGLADLAADLLSRLARLTGAAGGVVRLDRGDGMGRQLLARYGRAPRDNADTIRVPLDVHRPYSGELELDASPVGYAQALATMVAERFSLHLENDRLRRADVRRQTWITFLAEASELLAQSLDVNLTMALIPQLVVPRLGQWCAVHTTDAWGRLQLAAATHAEESQLADLHSSLAETGPESILARLEEASRLGTQVMFGTPSEGYAVPLVARGTRLGTLAVGRHPKHRHDADEVAVLEDVARRAALAIDNARIHDERRTVARTLQASLLPPALPHVEGIGFAAEYVPTGSEVGGDFYDVVPFGTDQHLVVVGDVSGKGVQAATVTGLVRDVIRILVDDGKAMSEILWRVNRTLVQRGGGRYCTLAMASVTRKGTSLGVCLHLAGHDRAVLVRADGKTSFVGEGGTALGLLETITSPDVVVTLDPGDSLIFYTDGVTERRRGRELFGSNRLREASAPLAGYPADVMAARLRSTTINFSVEEPRDDIAILVLRNDA
>NC_017093.1|WP_014440301.1|203288_207692_+|HAMP-domain-containing-protein
MTTAHEASVGVPDETVLLGELADALRRVRRGDLKVRLPRRSGMAGAVAEAFNEVVSLQERQNLDLRRISRIVGRDGRLTERLDEEGLDGSWADSVRSVNSLIDDLARPTTEISRVIVAVAEGDLSQHMALEMDGRPLRGEFLRIGRTVNTMVDQLSSFADEVTRVAREVGTEGELGGQADVRGVAGTWKDLTDSVNTMASNLTHQVRSISQVATAMARGDLSQKITVSARGEVAELSDTMNGLTDTLRLFAEQVTRVAREVGTEGKLGGQAEVPNVAGTWKDLTDNVNSMASNLTSQVRNIAQVSTAVAKGDLSQKITVAAQGEILELKDTVNTMVDQLSSFADEVTRVAREVGSEGRLGGQAQVRGVSGTWRDLTENVNQLAANLTAQVRNISQVSTAVAKGDLSQKITVDARGEIAELKNTVNTMVDQLSSFADEVTRVAREVGSEGKLGGQAQVKGVSGTWRDLTDNVNYMASNLTSQVRNIASVTTAVAKGDLGQKITVDARGEILELKSTVNTMVDQLSSFADEVTRVAREVGTEGKLGGQAQVRGVAGTWRDLTDNVNSMASNLTSQVRNIAQVSTAVAKGDLSQKITVDAQGEILELKNTVNTMVDQLSSFADEVTRVAREVGSEGKLGGQAQVRGVAGTWRDLTDNVNYMASNLTGQVRNIASVTTAVAKGDLGQKITVDARGEILELKNTVNTMVDQLSSFADEVTRVAREVGSEGKLGGQAQVKGVSGTWRDLTDNVNQLASTLTIQLRAIAEVSTAVTRGDLTQSVAVEAQGEVAELKDNINQMIVTLRDTTKTNAEQGWLDSNLARIGGLLQGQRDVGEVCRMIMTEVTPLVDAQLGAFFLVDNEEAVMRLRLNAAYGYVARDHEVTFGPGEGLVGQAAVSRRTIRVRATHDGILTMRSGLLAMPPNDLVVLPVLFEGEMLGVIEFASVAAFSGLHLTFLERLVANIGIALNTIQANRRTEELLTQSQRLAREMQDQSAELQRTNAELEDKAKLLSDQKANIELKNREIELARLGLEEKAQQLSRANTYKSEFLANMSHELRTPLNSLLLLARLLADNTEQNLTSKQIEFARTIHSAGSDLLSLIDDILDLSKIEAGRMDVEPDVVDFDGIRSYVEQAFLPQAEDKGLEFRVDVAPELPESIVTDPQRLQQILRNLLSNAVKFTDSGSVTLSIFPASPDVDLDAPSLLSARKVVGFAVTDTGIGISDEKLAIIFEPFQQADGTTTRKYGGTGLGLSISREFAALLGGTITVASVPGGGSTFTLYMPEALVPDAIPMPALPPVPAKAVSVRPATSLDIPLMELPQLAARQEEKKPAMTPAGRQLDGATVLIIDDDVRNVFALTSALEMHGLNVLYSDNGVDGVRILAEHPEVDIVLMDAMMPDQDGYETTRGIRRNQRFRDLPVVFLTAKAMPGDRESALAAGASDYITKPVDLDELIELMARWVNAKENTAPEHG

Crispr_ID: NC_017093_2

• CRISPR_ID: NC_017093_2
• CRISPR_location: 944735-944853
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_2

Consensus_repeat	Method
CCGTCCGCGTCACGCCAGCTCGCGCCGTCCCAGCCCT	CRISPRCasFinder

spacers of NC_017093_2

>2.1|944772|45|NC_017093|CRISPRCasFinder
GCGTGGCGGCCCCCGCTCGCCCGCGCCCGGTCCGTCCGCGCCACG

CRISPR arrays and Neighbor proteins around NC_017093_2

CRISPR arrays

The CRISPR arrays of NC_017093_2

>merge|NC_017093|2|944735-944853|CRISPRCasFinder
CCGTCCGCGTCACGCCAGCTCGCGCCGTCCCAGCCCTGCGTGGCGGCCCCCGCTCGCCCGCGCCCGGTCCGTCCGCGCCACGCCGTCCGCGCCACGCCAGCTCGCGCCGTCCCAGCCCT

>NC_017093|2|2|944735-944853|CRISPRCasFinder
CCGTCCGCGTCACGCCAGCTCGCGCCGTCCCAGCCCT	GCGTGGCGGCCCCCGCTCGCCCGCGCCCGGTCCGTCCGCGCCACG
CCGTCCGCGCCACGCCAGCTCGCGCCGTCCCAGCCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_014441001.1|948038_948554_+|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NC_017093.1|WP_014440996.1|941740_944647_+|preprotein-translocase-subunit-SecA	unknown	unknown	gnl|CDD|237259
NC_017093.1|WP_083888784.1|940748_941426_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NC_017093.1|WP_157435243.1|945151_945694_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014440992.1|937289_939128_+|GerMN-domain-containing-protein	unknown	unknown	gnl|CDD|237449
NC_017093.1|WP_014440998.1|945836_946064_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378935
NC_017093.1|WP_041830499.1|935664_937290_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_017093.1|WP_014440987.1|932042_933491_+|adenosylhomocysteinase	unknown	unknown	gnl|CDD|377487
NC_017093.1|WP_014440994.1|940127_940748_+|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl|CDD|129824
NC_017093.1|WP_157434733.1|933505_934525_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NC_017093.1|WP_014441003.1|949860_950541_+|cell-division-ATP-binding-protein-FtsE	unknown	unknown	gnl|CDD|225438
NC_017093.1|WP_014440993.1|939127_939847_+|ComF-family-protein	unknown	unknown	gnl|CDD|223970
NC_017093.1|WP_014441000.1|946630_947641_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014441005.1|951587_952811_+|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|366703
NC_017093.1|WP_014441004.1|950607_951483_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|225088
NC_017093.1|WP_014441006.1|952862_953339_+|SsrA-binding-protein-SmpB	unknown	unknown	gnl|CDD|376590
NC_017093.1|WP_014688036.1|934920_935610_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_017093.1|WP_014441002.1|948606_949719_+|peptide-chain-release-factor-2	unknown	unknown	gnl|CDD|234799
NC_017093.1|WP_041830498.1|934575_934779_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NC_017093.1|WP_172666662.1|946217_946679_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_014441001.1|948038_948554_+|PadR-family-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	1.97697e-06
NC_017093.1|WP_014440996.1|941740_944647_+|preprotein-translocase-subunit-SecA	gnl|CDD|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NC_017093.1|WP_083888784.1|940748_941426_-|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	4.92009e-29
NC_017093.1|WP_014441002.1|948606_949719_+|peptide-chain-release-factor-2	gnl|CDD|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NC_017093.1|WP_014440992.1|937289_939128_+|GerMN-domain-containing-protein	gnl|CDD|237449	PRK13616, PRK13616, MtrAB system accessory protein LpqB.	1.12969e-23
NC_017093.1|WP_014440998.1|945836_946064_-|helix-turn-helix-domain-containing-protein	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	8.78371e-09
NC_017093.1|WP_041830499.1|935664_937290_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	7.21815e-54
NC_017093.1|WP_014440987.1|932042_933491_+|adenosylhomocysteinase	gnl|CDD|377487	pfam05221, AdoHcyase, S-adenosyl-L-homocysteine hydrolase.	0
NC_017093.1|WP_014440994.1|940127_940748_+|ribosome-associated-translation-inhibitor-RaiA	gnl|CDD|129824	TIGR00741, Probable_sigma54_modulation_protein_ORF3_ORF95., ribosomal subunit interface protein. This model includes a small protein encoded by one of two genes, both downstream of the gene rpoN for sigma 54, whose deletion leads to increased expression from sigma 54-dependent promoters. It also includes the N-terminal half of a light-repressed protein LtrA of Synechococcus PCC 7002 and the N-terminal region (after removal of the transit peptide) of a larger plastid-specific ribosomal protein of spinach. The member of this family from E. coli is now recognized as a protein at the interace between ribosomal large and small subunits, with about 1/3 as many copies per cell as the number of ribosomes. [Protein synthesis, Translation factors].	4.33255e-29
NC_017093.1|WP_157434733.1|933505_934525_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.41186e-07
NC_017093.1|WP_014441003.1|949860_950541_+|cell-division-ATP-binding-protein-FtsE	gnl|CDD|225438	COG2884, FtsE, Predicted ATPase involved in cell division [Cell division and chromosome partitioning].	1.80161e-124
NC_017093.1|WP_014440993.1|939127_939847_+|ComF-family-protein	gnl|CDD|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	1.20467e-21
NC_017093.1|WP_014441005.1|951587_952811_+|M23-family-metallopeptidase	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	2.38687e-38
NC_017093.1|WP_014441004.1|950607_951483_+|ABC-transporter-permease	gnl|CDD|225088	COG2177, FtsX, Cell division protein [Cell division and chromosome partitioning].	4.25432e-63
NC_017093.1|WP_014441006.1|952862_953339_+|SsrA-binding-protein-SmpB	gnl|CDD|376590	pfam01668, SmpB, SmpB protein.	4.99814e-89
NC_017093.1|WP_014688036.1|934920_935610_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.11316e-84
NC_017093.1|WP_041830498.1|934575_934779_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	3.28927e-20

Protein sequences

>NC_017093.1|WP_014440996.1|941740_944647_+|preprotein-translocase-subunit-SecA
MSILEKILRAGEGRMVRRLKAIADAVNSIEDDYVDLTDDELRECTQQFKERYEEGESLDSLLPEAFAVAREGAKRVLGQRAYDVQLMGGAALHFGNIPEMKTGEGKTLTGVFPAYLNALSGKGVHIITVNDYLAQRDAEWVGRVHVFLGLTVGVILPNRPATEHRAAYQCDITYGTNNEFGFDYLRDNMAWSKTELVQRGHNFAIVDEVDSILIDEARTPLIISGPAEHSARWYGEFSQIVNRLQPGKDGEGDYEVDVAKRTVAITERGVAKVEDRLGIDNLYESVNTPLVGYLNNAIKAKELYKKDKDYIVSPEGEVLIVDEFTGRILHGRRYNEGMHQAIEAKEGVEVKQENQTLATITLQNYFRLYEKLGGMTGTAQTEAGEFNSVYKVGVVSIPTHRPMVRIDHPDVIYKTERAKFNAVIEDIAERHVTGQPVLVGTVSVENSEILSTLLRKRGIPHSVLNAKFHAQEATIIAQAGRKGAVTVATNMAGRGTDILLGGNPDFLAASELTQRGLDPVENPEEYAKALEEVLPSVKEACEQEASEVQAAGGLYVLGTERHDSRRIDNQLRGRSGRQGDPGESRFYLSLQDDLMKRFRAGAVEAVMERFNIPEDVPIESKMVTRQIRSAQTQIEAQNAEIRKNVLKYDEVLNKQRQVVYAERRRVLNGEDMHDQVTHMIDDVVADYVLAATSDGYAEDWDLEQLWTNLKRLYPVTLTIEDLIEESGGEKNTIDQEFLTEQLKQDAQAAYRAREEELGEEGVRELERQVLLAVIDRKWREHLYEMDYLQEGISLRAYAQRDPVVEYQREGFDMFNQMMEGIKEEAVGFVFNLEVQVEEQPTVTVDPSQAFELPNVGGPDTDDEPTGEPERVEVHAKGLGGPGRPQNLQYTAPAIDGEAGDGRPVIQQQSAPPNVGPGNTPVPASPAHTSARSASRAAGQESGGPSRNAPCYCGSGKKYKRCHGAPGAV
>NC_017093.1|WP_083888784.1|940748_941426_-|GNAT-family-N-acetyltransferase
MAAGFTREGARRLPGRELQVWSRLAGDPTEPAPRLLPDIPGGELTDGVVTLRPLGEQDVAFYTELHTLPEVVNTSVPPIPPTPEEVRRRCSRSEAQWLAGTRADLVILDSATGAPAGEIAVYYQEPPTNQAMIGYSLLPPYRGRGFTTRAAQLVALWAFAETDIVRLIAGTAPDNVGSQRVLERAGFRREAYLSSRLPGPDGTRIDDIQYVLLAGDLLAQASSGD
>NC_017093.1|WP_014440994.1|940127_940748_+|ribosome-associated-translation-inhibitor-RaiA
MDIVVKGRNVEVPDHYREHVAEKLSKVERYDPKLMRVDVELFHERNPRQSDTCQRVEITVMTRGPVVRAEAQAQDFYAALDCAINKLDGRLRRSADRRRVHRGRHAPVSVAAATANLPTDVSPGRTATLVAEPALDTELAEHGADQPWRIVREKEHSAEPMTVDDALFQMELVGHDFYLFQDKESGRPSVVYRRRGYDYGILSLGA
>NC_017093.1|WP_014440993.1|939127_939847_+|ComF-family-protein
MVAALLGELADLVLPGACAGCGAEQVRLTYGTCAVCVAELEGLRPHPATPTPPPAGFPDCVTVGPYAGALRGTLLAYKEKGRHRLARPLGTLLAGAVAALAPRGRPVVLIPVPSTAAARRERYGDHMARMTRHAMRRLRAAGWDATTIQPLRALPRPDSTSLDAAARHAAAVNSLRINPRIGVLQRGGRIGGTLVVTDDIVTTGATLAAVVRRLEEAGMQVTGAAVLAATQLRKTTPGI
>NC_017093.1|WP_014440992.1|937289_939128_+|GerMN-domain-containing-protein
MRRTHRHVQALPAVVALTALTFAGCGIPDDTGVTAVGPGPSTGISSGSENTSAQETRTSTSDRTEFVTNYLAAAAGDYDGATERVREFMSPPVAEKFKPVAIPRVIRLIGTPLVSQGRSTVQITYELIGTLGKNGLLEPPKEPVRGKYEITLGTAEDGISLYVLDAPPVLLISDTALASRYTRRTIYFWNTEHTGLVPDVRYLLHDVPIEQVPTTLLGWLIEGPAPWLRSVVEVLPEGTALQGKIPAIADQTLTITLSAQAVPTEGATEALDRLRRQLQWSLRPLPWENLALKIGHQETKNYYATDFLTSNAASRLEQFPERFAVYGGKIVRLSESRKAVAAIPAIPPQANKDVRTAALSTSATHTYAALVTGSGGGEALRVGSTLTSGGPDAALHAVSGLPGGLGYPVWALTADGDPESSLGLIIAGGGLYSFRAEGGAARQVQVSGVTGKISAITVAPDGHRAAIVAGGRLYRAVLTVSGDGVSLSEPELLRPPLDTVTAADFSGEGWLTVAGVRAGRVAVLDVTIDGALQDPRLPDLGDDTVTYVTAYPENPVNQSSNELGNADFVSFTTADAAWDVLSGPVQIVASSLAEPPSNRSANTVPTAPFFLN
>NC_017093.1|WP_041830499.1|935664_937290_+|HAMP-domain-containing-histidine-kinase
MPVRRALRVVRRYWRMVARRGRQYTAPARRAWRRSLQLRVVTLTLIGSSLLVSTFGWFIAAQSANILLNRTQDEISSSMSGKVAYAYSQLTLHPQARDPELPNTINDTVNDLVDGDQTENGGSIISIRAEHYQDLPAVTLPPVDTRDLITPDMIRTVAEQGQVAQQIRTAEVGGATTKYLVYGSPVPTKFGHLELYYMVPLTTEDRAANQIRTTVLITGIALVILLGVVAALVTRMVVTPVRVAARTAQRLSAGLLDQRMKVDGEDDLALLAAAFNQMAANLQRQIVRLEEMSRLQRRFTSDVSHELRTPLTTVRMAADLIFSEREDFDPAVARSAELLQAELDRFEGLLTDLLEISRFDAGFAALDAEHTDLVPIVERVAERLSGLAERAGVDVELRLPDTPVIAEVDPRRVERVLRNLVGNAIEHAEAKPVVVTLSTDEAAVAVTVRDYGIGLKPGEERLVFNRFWRADPSRARQTGGTGLGLSISVEDARLHGGWLEAWGAPGEGSQFRLTLPVRAGDRLVAAPLPLIPRDRPAEVTG
>NC_017093.1|WP_014688036.1|934920_935610_+|response-regulator-transcription-factor
MRARVLVVDDDPALAEMLGIVLRSEGFLPSFVADGERALAAFRENRPDIVLLDLMLPGMSGIDVARAIRAESGIPIVMLTAKSDTVDVVLGLESGADDYVVKPFKPKELVARMRARLRRGEDAAPEMLTIGPPGNQITIDVPAHTVSRDGEEVKLTPLEFDLLVALARKPRQVFTREVLLEQVWGYRHAADTRLVNVHVQRLRAKIEPDPERPEIILTVRGVGYKAGTG
>NC_017093.1|WP_041830498.1|934575_934779_+|DUF397-domain-containing-protein
MQNATLTWRKSSRSGAAGHCVEVAEVPAAVLVRDSKDVTGPVLTFGAGDWTGFIAGVRAGEFDRPGA
>NC_017093.1|WP_157434733.1|933505_934525_+|helix-turn-helix-domain-containing-protein
MPEPPLARRTGALVSPGFAALGGRLSPIITSRWSSALQVQCVSATCNGASIRRYGGSVARPTSTARRELGGELRRLRGERRAVDVATALGWSESKLSRIETAHTGISEADLDRLLTLYGVAVEDRSRLRDLARRGRARAWWTPYRSSVPDPYDEYLALEGEAVRISEWEAQVVPGLLQTHEYARAVIETGADIDDTDTISRRLALRMRRQDVLTRDPPPNLRLVIDEGVLLREVGGRDVQHRQLSRLYEASTRPGVELQILPFQAGAHAGLIESFLVMEFAPGTRNPVVHIEGLTGGLFRVKPEEIDVYGDAFDDLQERALSLEESRTAIAETRDRLAR
>NC_017093.1|WP_014440987.1|932042_933491_+|adenosylhomocysteinase
MEGVFVGDFKVADLSLAAFGRKEIELAEHEMPGLMALRAEYGPSQPLRGARITGSLHMTIQTAVLIETLTALGAQVRWASCNIFSTQDHAAAAIVVGRDGTAEDPKGVPVYAWKGETLEEYWWCTEQVLLWPDGEAPNMILDDGGDATLLVHKGAEFEKAGVVPPAESASSEEYAVILGLLARSLKEDGRRWTRVAAGIKGVTEETTTGVHRLYEMQQQGTLLFPAINVNDSVTKSKFDNKYGCRHSLIDGINRATDVLIGGKVAVVFGYGDVGKGCAESLRGQGARVIVTEVDPICALQAAMDGYQVATIDEVVKYADIFVTATGCFDVITHEHMARMKHQAIVGNIGHFDNEIDMAGLAARKDVRRVTIKPQVDEWQFDDGHSIIVLSEGRLLNLGNATGHPSFVMSNSFSNQTIAQIELFTKTEEYPVGVYVLPKKLDEKVARLHLDALGVKLTELTKQQAAYLGIAVEGPYKPDHYRY
>NC_017093.1|WP_157435243.1|945151_945694_-|hypothetical-protein
MPRYEPPFDDELAPQVWSPPRQQLALDWSTPAPPPAQSEGGPTGGAASRSTGQPAGPPAAEVPGASGDAKLAVRRFVHLSVEVLNGFRPAGHLRRLSLPSHAADVVAAGLAGAQWVGQLRRAKKTRRPAPVAVLKVHLCEPRAGAVEAAVVLVTGERTWALALRMELHQQTWLATTLRLI
>NC_017093.1|WP_014440998.1|945836_946064_-|helix-turn-helix-domain-containing-protein
MEPRFLLLTDVAAELNVSDSQVYHMVRSGELPAIKIGGRGQWRVERTRLEEYIQHKYEETAAWVRDNPLTEREAE
>NC_017093.1|WP_172666662.1|946217_946679_+|hypothetical-protein
MLAALRQSGQLGDSAAEAHAVTPALREWYAEGDEEELEYVAFTRAAQGALRLLRHDPSAPRRRVVVSADVPASALVREDTELGSSSVRLPAPIRLTEVASIHLDGADAAEAVAAAADVVEEALAGDPDAQFTVDSAEDHELEWYAVSELDELT
>NC_017093.1|WP_014441000.1|946630_947641_-|hypothetical-protein
MTDRHTAAESARPTVAESARHTAAESVEESRLTVALIAAAALAWTAAMLWSARTTITGRISAEMEVTSTAYALPGAVAADLVAGAAVALLVLTLIGSRRTLGASLRFAVATGAGLLVGVLSAIPIITINTAGSLYAIVGGTVAAAATIGGALAGFRVPPVIAAGAAASVGVFVLGFVLNLFQAPVLELLGAGDTESSAKAAQWFSYGQAALSGLAAGLIAYFMLRRHRRRAAGADVKWPLYALAGAGAGLVTVIGEILSRTAGSQVLDLAGKVSEMDRLAQDILSTARLNSGLIVLFVGAMTAMLAVGRTLSPAAEDEDEAQVNSSSSETAYHSNS
>NC_017093.1|WP_014441001.1|948038_948554_+|PadR-family-transcriptional-regulator
MPDFQINPTAAALLGLLHEGPMTGGQLMAAAERRLGPYWSMTRSQVYRELPVLAEMGYVRLGKPGPRSSQPYAITASGKRAFTRWLTESPGRDALRNPVALRVAFGQQHSGDQLEVLYSNANQYHSEAMAMAKEQAKEAKKNGDPYGAAALEFAVAYHKAALTWLKAAPTG
>NC_017093.1|WP_014441002.1|948606_949719_+|peptide-chain-release-factor-2
MTAADFAEQIKVLDATLRNIETVLDVDRLRRDKADLEEQASAPDLWDDQARAQEVNSRLAYVSGEISKLERLRSRLDDAGLLLEMAEAESDEGSIAEVGDEITTLTKAVEEMEVRTLLSGEYDSREALVAIRAGAGGVDAADFAEMLMRMYLRWAERHGYPTEVYDTSYAEEAGLKSATFAVKVPYAFGTLSVESGTHRLVRISPFDNQGRRQTSFAGVEVMPVVEQTDHIDIPDNEIRVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVASCQNEKSQLQNKAAAMRVLQARLLERKRQEDAAKMADLKQDTTGSWGDQMRSYVLHPYQMVKDLRTEFEVGNPTGVFDGDLDGFIQAGIKWRKQNQMSA
>NC_017093.1|WP_014441003.1|949860_950541_+|cell-division-ATP-binding-protein-FtsE
MIQLENVTKTYPKASRPSLDNVSVGIEKGEFVFFIGPSGSGKSTIIKLLLKEVSPSSGKVVVNAKDVTSLRSWKVPHFRRSIGCVFQDFRLLPNRTAYENVAFALEVIGKTKAVARRVVPEVLELVGLGGKEHRYPHELSGGEQQRVAVARAFVNRPLILLADEPTGNLDPDTSIEIMRLLDRINRTGTTVVMVTHDSNIVNQMRRRVIEIESGRIVRDQARGVYG
>NC_017093.1|WP_014441004.1|950607_951483_+|ABC-transporter-permease
MRVKYVLNEVLVGLWRNVTMTIAMIITMAVSLTMFGASVLMYMQVDRMKDFYYGEIEVSIFLNDDVDEAQRAAIDQAIDSNPLVKEKTYETKEQAFERFKVLWEDSPDFVNSISASSLPESYRVKLNDPEKYADFAKEIESLQGVRQIIDQRTLLDKVFKIFNSIQVMSLVVAAVMAFAALLLVGNTIQVAAYSKRREVAVMKLVGASNWFIQAPFVLEAVVAGLIGAVLGFIALFIGKVVLLDNKLQALTTILTPIPNGNVWLMLPLLAGVGALVSAVTAWVTLRFYLKV
>NC_017093.1|WP_014441005.1|951587_952811_+|M23-family-metallopeptidase
MRYRRSVALLTVCLCWLAFHPAPAAADRSGDAARAVRRAEALLESASVTARAAARRLAAATAAMPAAQRRVATTRGVVVATRVEAATARRQAERARAEYAEVADFYATAAARVNDARDRVDQIAATTYMGSTFARINVLVTATGPQDMLDRMGLVQQVMGHEQTEVRTLIGARRDARAAQDRAGAAKRVAEEYERIAVTKLRAAQAAQAAAVKARQAMYQLVLARQTALRAAQAQRATVLAQYRAALATERKVQAALRGYDSRAGGVRSYGGGRLTMPVQGWKSSDFGNRYDPYYRVWQLHAGTDFAAGSGTAIRAAASGRVIQAGWAGGYGNYTCINHGRLGRYGFTTCYGHQSRMYVHRGSYVRRGQVIGRVGSTGASTGAHLHFETRFGGVPRNPLRYLPGCLC
>NC_017093.1|WP_014441006.1|952862_953339_+|SsrA-binding-protein-SmpB
MPREQGRKPVASNRKAYHDYTILDTYEAGMVLTGTEVKSLRAGRSSLVDAFGHEKDGEIFLHGMHIPEYTQGTWTNHEPRRVRKLLLNREEIHKILGKLRDDGVTLVPLSVYFHNGYAKVEIGVAKGKKSYDKRQDLASRDAQREINRALGRRAKGMD

Crispr_ID: NC_017093_3

• CRISPR_ID: NC_017093_3
• CRISPR_location: 1095286-1095383
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of NC_017093_3

Consensus_repeat	Method
ACCTGCGGGTCCTCGAAGGTGCC	CRISPRCasFinder

spacers of NC_017093_3

>3.1|1095309|52|NC_017093|CRISPRCasFinder
CTTGTCGTCGACGGCCGCGTCGACCGGGTCGGTCCGCTCGGCCTCGTCCAGA

CRISPR arrays and Neighbor proteins around NC_017093_3

CRISPR arrays

The CRISPR arrays of NC_017093_3

>merge|NC_017093|3|1095286-1095383|CRISPRCasFinder
ACCTGCGGGTCCTCGAAGGTGCCCTTGTCGTCGACGGCCGCGTCGACCGGGTCGGTCCGCTCGGCCTCGTCCAGAACCTTCGGGTCCTCGAAGGTGCC

>NC_017093|3|3|1095286-1095383|CRISPRCasFinder
ACCTGCGGGTCCTCGAAGGTGCC	CTTGTCGTCGACGGCCGCGTCGACCGGGTCGGTCCGCTCGGCCTCGTCCAGA
ACCTTCGGGTCCTCGAAGGTGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_051042387.1|1087417_1088377_+|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
NC_017093.1|WP_041829564.1|1099699_1100122_+|roadblock/LC7-domain-containing-protein	unknown	unknown	gnl|CDD|367422
NC_017093.1|WP_014441150.1|1103889_1105593_+|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|238733
NC_017093.1|WP_041829563.1|1089536_1090970_+|family-20-glycosylhydrolase	unknown	unknown	gnl|CDD|119336
NC_017093.1|WP_041830525.1|1086398_1087352_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224054
NC_017093.1|WP_014441131.1|1084567_1085641_-|magnesium-and-cobalt-transport-protein-CorA	unknown	unknown	gnl|CDD|213364
NC_017093.1|WP_014441135.1|1088466_1088973_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_017093.1|WP_014441147.1|1101109_1102177_-|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|380502
NC_017093.1|WP_014441148.1|1102282_1102474_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014441132.1|1085658_1086396_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|130314
NC_017093.1|WP_014441152.1|1107409_1108594_+|xylose-isomerase	unknown	unknown	gnl|CDD|237170
NC_017093.1|WP_014441146.1|1100478_1101078_+|ATP/GTP-binding-protein	unknown	unknown	gnl|CDD|225138
NC_017093.1|WP_014441138.1|1090982_1092191_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NC_017093.1|WP_041829565.1|1100111_1100498_+|DUF742-domain-containing-protein	unknown	unknown	gnl|CDD|283084
NC_017093.1|WP_014441149.1|1102582_1103641_+|lactonase-family-protein	unknown	unknown	gnl|CDD|378416
NC_017093.1|WP_014441136.1|1088965_1089511_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_017093.1|WP_157434738.1|1092208_1094269_+|M48-family-metalloprotease	unknown	unknown	gnl|CDD|320687
NC_017093.1|WP_014441140.1|1094417_1094945_+|hypothetical-protein	unknown	unknown	gnl|CDD|236138
NC_017093.1|WP_014441143.1|1097075_1099703_+|nitrate--and-nitrite-sensing-domain-containing-protein	unknown	unknown	gnl|CDD|377989
NC_017093.1|WP_041829566.1|1106189_1107335_-|ROK-family-protein	unknown	unknown	gnl|CDD|224851

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017093.1|WP_051042387.1|1087417_1088377_+|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	1.2e-55	183.9	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_051042387.1|1087417_1088377_+|YafY-family-transcriptional-regulator	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	6.28585e-50
NC_017093.1|WP_041829564.1|1099699_1100122_+|roadblock/LC7-domain-containing-protein	gnl|CDD|367422	pfam03259, Robl_LC7, Roadblock/LC7 domain. This family includes proteins that are about 100 amino acids long and have been shown to be related. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions. This family also includes Golgi-associated MP1 adapter protein and MglB from Myxococcus xanthus, a protein involved in gliding motility. However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.	2.03719e-21
NC_017093.1|WP_014441150.1|1103889_1105593_+|substrate-binding-domain-containing-protein	gnl|CDD|238733	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Not much is known about the function of the members of this subgroup. All members of this subgroup however have a conserved MIDAS motif. .	1.30448e-23
NC_017093.1|WP_041829563.1|1089536_1090970_+|family-20-glycosylhydrolase	gnl|CDD|119336	cd06568, GH20_SpHex_like, A subgroup of the Glycosyl hydrolase family 20 (GH20) catalytic domain found in proteins similar to the N-acetylhexosaminidase from Streptomyces plicatus (SpHex). SpHex catalyzes the hydrolysis of N-acetyl-beta-hexosaminides. An Asp residue within the active site plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself. Proteins belonging to this subgroup lack the C-terminal PKD (polycystic kidney disease I)-like domain found in the chitobiases.	1.3034e-171
NC_017093.1|WP_041830525.1|1086398_1087352_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	8.23112e-98
NC_017093.1|WP_014441131.1|1084567_1085641_-|magnesium-and-cobalt-transport-protein-CorA	gnl|CDD|213364	cd12830, MtCorA-like, Mycobacterium tuberculosis CorA-like subfamily. This bacterial subfamily belongs to the Thermotoga maritima CorA (TmCorA)-like family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. This subfamily includes the Mg2+ transporter Mycobacterium tuberculosis CorA (which also transports Co2+). Thermotoga maritima CorA forms funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport by a related protein, Saccharomyces cerevisiae Alr1p. Natural variants in this signature sequence may be associated with the transport of different divalent cations. The functional diversity of the MIT superfamily may also be due to minor structural differences regulating gating, substrate selection, and transport.	4.73833e-138
NC_017093.1|WP_014441135.1|1088466_1088973_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.88435e-11
NC_017093.1|WP_014441147.1|1101109_1102177_-|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|380502	cd06279, PBP1_LacI-like, ligand-binding domain of an uncharacterized transcription regulator from Corynebacterium glutamicum and its close homologs from other bacteria. This group includes the ligand-binding domain of an uncharacterized transcription regulator from Corynebacterium glutamicum and its close homologs from other bacteria. This group belongs to the LacI-GalR family repressors and are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding.	5.34898e-78
NC_017093.1|WP_014441132.1|1085658_1086396_-|ABC-transporter-permease	gnl|CDD|130314	TIGR01247, drrB, daunorubicin resistance ABC transporter membrane protein. This model describes daunorubicin resistance ABC transporter, membrane associated protein in bacteria and archaea. The protein associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	4.52723e-21
NC_017093.1|WP_014441152.1|1107409_1108594_+|xylose-isomerase	gnl|CDD|237170	PRK12677, PRK12677, xylose isomerase; Provisional.	0
NC_017093.1|WP_014441146.1|1100478_1101078_+|ATP/GTP-binding-protein	gnl|CDD|225138	COG2229, COG2229, Predicted GTPase [General function prediction only].	4.68187e-38
NC_017093.1|WP_014441138.1|1090982_1092191_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	6.23752e-33
NC_017093.1|WP_041829565.1|1100111_1100498_+|DUF742-domain-containing-protein	gnl|CDD|283084	pfam05331, DUF742, Protein of unknown function (DUF742). This family consists of several uncharacterized Streptomyces proteins as well as one from Mycobacterium tuberculosis. The function of these proteins is unknown.	1.35081e-26
NC_017093.1|WP_014441149.1|1102582_1103641_+|lactonase-family-protein	gnl|CDD|378416	pfam10282, Lactonase, Lactonase, 7-bladed beta-propeller. This entry contains bacterial 6-phosphogluconolactonases (6PGL)YbhE-type (EC:3.1.1.31) which hydrolyze 6-phosphogluconolactone to 6-phosphogluconate. The entry also contains the fungal muconate lactonising enzyme carboxy-cis,cis-muconate cyclase (EC:5.5.1.5) and muconate cycloisomerase (EC:5.5.1.1), which convert cis,cis-muconates to muconolactones and vice versa as part of the microbial beta-ketoadipate pathway. Structures of proteins in this family have revealed a 7-bladed beta-propeller fold.	5.21619e-111
NC_017093.1|WP_014441136.1|1088965_1089511_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.32461e-11
NC_017093.1|WP_157434738.1|1092208_1094269_+|M48-family-metalloprotease	gnl|CDD|320687	cd07328, M48_Ste24p_like, M48 Ste24 endopeptidase-like, integral membrane metallopeptidase. This family contains peptidase M48-like proteins that are as yet uncharacterized, but probably function as intracellular, membrane-associated zinc metalloproteases; they all contain the HEXXH Zn-binding motif, which is critical for Ste24p activity. They likely remove the C-terminal three residues of farnesylated proteins proteolytically and are possibly associated with the endoplasmic reticulum and golgi.	1.7434e-24
NC_017093.1|WP_014441140.1|1094417_1094945_+|hypothetical-protein	gnl|CDD|236138	PRK07994, PRK07994, DNA polymerase III subunits gamma and tau; Validated.	1.07804e-06
NC_017093.1|WP_014441143.1|1097075_1099703_+|nitrate--and-nitrite-sensing-domain-containing-protein	gnl|CDD|377989	pfam08376, NIT, Nitrate and nitrite sensing. The nitrate- and nitrite sensing domain (NIT) is found in receptor components of signal transducing pathways in bacteria which control gene expression, cellular motility and enzyme activity in response to nitrate and nitrite concentrations. The NIT domain is predicted to be all alpha-helical in structure.	1.55549e-25
NC_017093.1|WP_041829566.1|1106189_1107335_-|ROK-family-protein	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.13434e-40

Protein sequences

>NC_017093.1|WP_014441140.1|1094417_1094945_+|hypothetical-protein
MARGPSTLFGAIVAVGVGPALWLGAQLGTADVAPNERPSTVVGEQGPESDIDFGGVGAGETPDQADWIRVYPDSGDDGETAPSPAVKRTSMSPAAVVVTPGSPSPSPSSPAVASSPPPSPPPSDPVVPPSPSFEGEPSSEPSAEPSDEVTEDPEPSVSAPPEENEAPEPLYSAHE
>NC_017093.1|WP_157434738.1|1092208_1094269_+|M48-family-metalloprotease
MRGRETRLGRFLGEDDGLSRGARSAAALAGFVLVAGAQLALVLLALGAVLWLLPSTVALRAGVPLSIATFGAAGYATWRALHTRRRLPAGVTVTRDRAPRLWDLVDAAAVAAGVPSPATLAVVADAGVTVGERTRLLGLVGGRRDLYLGLPLLQAWGPDRLSAAVTHELAHYSPRLSRWAPLAYRGRVAVGRVAPRISRRNPAGIALRAWAGLYRRIDTPFSREQELAADRIAAGHAGAEAVAAVLRDLPALAGMQRLFHAEYLGPGWQAGYVPDDVFGGLLRVLAARSAEMAVLRGQEPEPAGPWDTHPPLAERLASLAPPESSDAAKDSDAPGETVAPGETVAPGETDSPDQTDSPDETVERVPDLPQLGRALQDVAYPAGGRTIVTWDECLSIARTAEMEREAEAALATISRAVGAEISGPAQVLDLAADGRLRSAAETLFPGASPGAATDRIIDLLGLMMALAALRSGIVRWRHSWTGAAEVVGVDGAYLNLAELAQAAAEPETVPAVREYLEKIGVDLAAPAGDGGPARPVLGGLVNLTVDGSRTDLLITDLGLLLVPGLPRGRGPESKRRLARIAADGVPVTARPEPASTPEPGSRFLPFADVTGVTALPGRRKGWTIEVRDGDGVTLRPALDTDELLGGWKVWEETVTFLTGTRPVVPAARPPAEGVAEPGAVDARTGG
>NC_017093.1|WP_014441138.1|1090982_1092191_-|cytochrome-P450
MADLDQTLAVALKGYAWLPDLRRRASGAPVRTRVMGQPAVGICGPAAAQFFYGAGNLERHTALPSLVVHTLFGAGAVHTLDGSAHRHRKALFSGLLLGEDGIDTLAKLAGEAFDGAAAGWRGGREISLFDETARIIAKAVTRWVGVPEEERELTALARDLVAMVDGFATVGPRFARALAARERQERILSKTIARVRAEAPTPEPISVIAHHTDDGVLLDPRTAAVELLNVIRPSTAVAWFVAFAAHALDRWPRHAARLRAGDDEFTTAFVHEVRRFYPFAPFLGGRAARDLHFQGEPIPSGTLVLLDVYGQNHDPDLWEDPYAFRPERFLGREIGDFDLIPQGGGDPRTGHRCPGEKITIALLGTLIQHLARLDYYLPPQDTTIDLSRIPAIPRSRIKLVVP
>NC_017093.1|WP_041829563.1|1089536_1090970_+|family-20-glycosylhydrolase
MRPLTKRLGDVIPHPASVRPAPAASFTITEGTGVTAVPEAAGVAAHLAAELARVTGGTIPIGPGGAIRLELDPSLPAEGYTCEITDDAVTLRGGTPQGLFWGVQTLLQLAPVLPGGVIEDAPRYEYRGAMLDIARHFFTADEIKAHIDLLVQFKINHLHLHLTDDQGWRLEIPGWPKLTEISGGAGTGVDGAGPGFLTLAEYTGIVDYAAARFVTIVPEIDMPGHVNAVHHAYPELTADGQPVPQRTDAEVGYSSLVAGKEETYAFVEDVIRTVADVTPGPYLHIGGDECLSTPAEDYRAFLGRVLPLPGKYGKRAIGWHEIAAVELPETAVVQFWRIEATDDDTARAAADGRRVIMAPADRTYLDMKYDADTRIGLDWAGHVDVRRSYEWDPADRLPGVPESALLGVEAPLWSETLRSVADVQYLTFPRLPAIAEVAWSPRSVRDWDSFRTRLAAFAPRWAAAGVSYHPSAEIPWP
>NC_017093.1|WP_014441136.1|1088965_1089511_-|GNAT-family-N-acetyltransferase
MTITTRHGLLGDEQLLHDLAVRTFGLACPPSMAQADIDAFVAAHLSVDSFTRYLSDPNRIIVLVSEDDQPVGYSMLVCDRITDPDVAAVVDEATSIELSKFYLLAEAHGSGAAQALMTATLATAARTGAETCWLGVNQQNVRAAKFYAKHGFDIIGVKRFLVGSEWCDDHIRQRALSSRDG
>NC_017093.1|WP_014441135.1|1088466_1088973_-|GNAT-family-N-acetyltransferase
MAEVRAAHATDVAAIHDICTKAFHATYQGVLPAGYIGRMLAEFYPPDRIAGRIAPDSPGWLGYQVVEEGGRVLGVAAGGLTAASAAELFMMYLEPSERGRGLGTLLLNRVTEQVRELGATELWVAAVVGNDLGVPFYEARGFTIQSKRRAYGSTDAEDVWSWLLRRSL
>NC_017093.1|WP_051042387.1|1087417_1088377_+|YafY-family-transcriptional-regulator
MANTSARMLRLLSLLQTHRYWPGSELADRLEVSPRTLRRDVDRLRELGYPVDASRGVAGGYQLQAGAAMPPLLLDDEEAVAIAVGLRSAAAGAVAGFEETSVRALAKVIQLLPPRLRRRIDALQAVTAPGVLGGGPVLDAVTLTTIAMACRGEERLRFDYAPRDGEAMRRHVEPHRLVSLGRRWYLVAWDLDRGDWRSFRVDRLSGPSLTGARFRPRELPGGDPVVWLRSRLATIPSRYEVSVLIEAPEDTVRSFIGHWGAVTPVTASSCRLTMSVDDLGWPIMVLGVLSAPFVIESPAELRDRARRAGETLIRNTTVS
>NC_017093.1|WP_041830525.1|1086398_1087352_-|ATP-binding-cassette-domain-containing-protein
MIETRELTKMFKDVRAVDGINLTVARGELVALLGPNGAGKSTTLRMLTTLIPPTSGSAQVAGFDVVRRQRDVRLRIGYIGQGNGAGHSQRGRDELISQGRAYGMPVRAARTRAGELIDSLGLSDVADRTVSTLSGGQRRRLDIAMGLIHAPELLFLDEPSTGLDPQNRANLQEHIVRLRAEHGTTIVLTTHYLDEADSMAERVIVIDHGRIIADDTPQQLKAKHVGDRVILGFGSPVDAAQAAKALGAPVADGCVRLVAEDGPREAPRILDSLRSAGLAPDSIEVKRPTLDDVFLTLTGRSLREGGAADTEPELVEA
>NC_017093.1|WP_014441132.1|1085658_1086396_-|ABC-transporter-permease
MSSLVTDTRVVFSRELRPVIRDPFSVIFSMVQPLFFLALFAPLLPGEESLQWFVPGIIVMSCLFGSSMTGSNLLFEMQTGSHERMLVTPLRRPALLIGRALKEIVPMIAQAALIVAVCIPFGFELHLPGTLIGLGILAGFCIGLGALSYTLALAAKNKEWLFWTVQQTLLFPLLLLAGVLLPIDNGPGWLQALSRANPMTYVVDAERALFAGDIWGRHTAEGLIAAVLVAALGLLVGVRAMQRSD
>NC_017093.1|WP_014441131.1|1084567_1085641_-|magnesium-and-cobalt-transport-protein-CorA
MRGALGRLLENIVRTPKPAVQVPHGDPDAVVDCAVYAGGARRSGPRQIPYAEAARLAGRRGSFVWLGLHEPSRSTMTAVAEVFGLHELHVEQAVSGGHRPGVEVLGDVTRLVLRTARYVEHDELTATSEVVETGDVTILVGPAFAITVRQGPVGPLALVRRELESRPEVLRQGPWSVAYAVGSRMVDSYLDVAEHVEHDLDRIEEETFATVRSSEFAHIYQLKREMVEFKRAVLPLGEPMTRLLELRDVPAALRPYLVDVRGRLARAADRVGGFDELLNSILQARLAQVSVDQNHDMRKIAAWAAIAAVPTVIAGIFGMNFEVMPGLDSPYGFWGAMLAMVLIGGGVHRSLKKYGWL
>NC_017093.1|WP_014441143.1|1097075_1099703_+|nitrate--and-nitrite-sensing-domain-containing-protein
MRSRNWSIRSKITAMVAVPLAALLALWIFATVVTAGPALNLIEARDAVHKLGNPGLQLIAQLQRERHFSAIYVSAAKPTATDLNRERAATDEAATTFRRAVAEADLTESVRTRVDEMLALLDELPETRAGIDDRLIKDVLPVVRDFSAVIDAAFEVSATAAIFFHERVDREVRGLIDALKGLEHLSRVDAMLAGANAAGYIHAINRGILIEDIANSRYLLKSGVEDMPESARGDYSRVITSPAFVDLDIMQNSLIGDSYAGGPPPVSGESWQPTYDRTNAELSDFVLRSVDEVAEDAVPLAASVLLRLGIAGLLGLVAFVLSIFVAVRFGRSIVGRLIRLRREALEMASERLPAVVRRLQRGEAVDVEVETPPLEYGGDEIGQLGHAFNAVQRTAVQSAVDEANVRRGINEVFLNIARRSQTLLHRQLSLLDKMERRETEPQELEDLYRVDHLATRMRRHAEDLVILAGAAPGRGWRNPVPIIDVVRGAISEVEDYKRIDIRTITSSAVLGRAVGDVIHLLAELIENAASYSPPHARVQVVGQVLPNGYAIEIEDRGLGMAPEAIEETNRRLAEPPDFDPTDSARLGLFVVAQLANRHQIRVSLRASAYGGITAIVLLPGDLVTSVPGPALPIGPASGGLDTPLVGSGSEDPLRQSLASLQWQGTGELREVTVPGRRGAAEETPADAVTDPGGPAPSLIADELSAEGLVQRRRVRRKPNPPIEMPGESTGGIRAVPRNSGPSAPPPETPVVPAQRRPSAAETTDDDGLPKRVRQASLAPQLRQPAVEQESTAPARSPEQVRTLMSALQLGTNRGRVDAARTETAAAETERADDTVSFPTLVDVTAARDNAPSGTDAADGDRAYGTGENLRLEKDA
>NC_017093.1|WP_041829564.1|1099699_1100122_+|roadblock/LC7-domain-containing-protein
MVAQTKQSANLTWLLDDLVERVPTAQQAVVLSADGLMLGASAAMSREDAEHLSAMAAGFQSLAKGASRHFQAGQVRQTVVEMEEAFLFVTAAGQGACLAVLASADADLGLIAYEMAMLVTRVGQIMSAPERSVLAPSDAL
>NC_017093.1|WP_041829565.1|1100111_1100498_+|DUF742-domain-containing-protein
MPSEQPRVTHDWLDSDAGPVVRPYAMTGGRVAPSDGDFDLVAFVVATVPDLPIGPQLQPEHHAIVAAAWEPISVVELASQLDLSIGVVRVFLGDLRSAGLISLYEPPAATQPHDVDVLKAVVNGLRAL
>NC_017093.1|WP_014441146.1|1100478_1101078_+|ATP/GTP-binding-protein
MDSVRSDRNGGSSRIPVALKILIAGGFGAGKTTMVGSVSEIRPLQTEEVLTGAEGADDVSGVEGKTTTTVTMDFGRITITEDLQLYLFGTPGQDRFWFLWDELSQGALGAVVLADTRRLADCFPSIDYFEQRGTPFVVAVNCFDTQQRFAPEAVSRALDLDPGVPVVLFDARDQVAARNVLIELVEYVARRQLAAAGSR
>NC_017093.1|WP_014441147.1|1101109_1102177_-|LacI-family-DNA-binding-transcriptional-regulator
MPRVTLQTIADRVGVSRMTVSNAFSRPDQLSPALRERILAAAQDLGYVGPDPTARALAKGTTGAVGILLTDSLRYAFTDLVAGGFLAAIAGELAPTGLAITLLTSAAAGDVVPARDVAIDGAVVYSCDPTSPAVSWLRRRNLPMVFVDQDQVDDVASVNIADRAGARAAAQHLIDLGHRRFAIAMNGENGRHGFITDPSTLIEGHASHQRRLGWSDVLEPAGVKPAFLRHPLEKTEDVRRDARVLLAAEDRPTAFLCFSDTTAVGVRQAAEDLRLRVPEDLSIVGFDDGPDAVRMQPALTTVRQDVVAKGQAAAAALTEAIRRSRGGPAGPVPHIMLPTELVIRDSSGPAPRTPV
>NC_017093.1|WP_014441148.1|1102282_1102474_-|hypothetical-protein
MELPAAYLRGVQDVTREVLSARPDAPVVAEAEPVARTPWLRASLANALYRASCAVAPAGHRPA
>NC_017093.1|WP_014441149.1|1102582_1103641_+|lactonase-family-protein
MVSSAEYVFVGCYTGDKGGEGDGITLLRRDPATGDLTRLGLAARTPSPSFLAQHPTLPVLYAVNELDQGTITAFSVAPDCSLIPLGTQSTGGADPCHLAVTGDGRHLVVANYGGGSVAVFPLDADGVPAGRSDLLQLQGSGPNAERQSSPHAHQVVPDPNGADVLISDLGSDRVWRSRLDPVSGRLSLPDPAVEAKPGTGPRHLVRSTGGTVLLAGELTGDVSWYRPAGGPTLTPAGTVAASQSSGAVHPSEIAIRNDGRHVYVANRGPDTVSAFSWDGESLTLIAEVPAGGVWPRHMVLLGDHLYVANQRSHNVTVFRVDPDTGIPGSQGEPTGEPSPTCLLRWNPPMIRP
>NC_017093.1|WP_014441150.1|1103889_1105593_+|substrate-binding-domain-containing-protein
MAIVVVIAGTWLGYQQLADSGCTGSVRLSVAAAPEIAPAVQQIAQQWTAGGAEVSGTCVAVDVADENPADIAGAVSRDHDVALAGLGTAPESVVVPDVWLPDSSTWLLRLQQEAPGFKPTKIASVAQSPLVLAMPEPVAKNFGWPDKKMAWRDLLAQFGTESTLQVGIVDPTRDAAGLTSLLAVGANAGTTQEGKLKKVQVLTALAENRSALREELLQQFPKSTDANDLGNSLQAAPLSEEDVVAFNAQRPAVQLSALYMEPAPQPLDYPYAVMPQVVDTQKAAAADALLAQLAGAGFKENLATVGLRAPDGTYGSGFQAPVGAPAASPAVKSSSGSEGGGKAASGVSGKELSQAVGSWVATTLPGRVLAVFDVSGSMDKAVPTAGGATRAQVTQDAARGGLALFNNKWAVGVWRFSTKLDGNLPYKELVPITPLTSGRQRLQESISDLDPVPAGNTGLYDTVLAAYKEVQKNWKAGRSNSVILFTDGENLNEDGLERGEFLDQLKKAVDPKRPVRLVLIGIGNEVNKAELDEISATVKGSGVFIAQDPARISDIFLEAIGTRTGAN
>NC_017093.1|WP_041829566.1|1106189_1107335_-|ROK-family-protein
MTARLTSRSSAPVRQSSVRAHNLALVLHTVANSTDRLSRAGVAAVTGLTRATVSALVDDLIAGGLLTELDPPPRTGAGRPAVGLALSAAGPAGLGCEINVDYLAACVVDLTGAVRQRFVEHADQRASDAAGSLEALGRLAARARLAAEAEGLTVAGAALAVPGLVTGDGVVRVAPNLGWQDVDAPALLRAVPELADLPIGVDNEANLAALGELLVDPAFLSGGGRPTFLYVSGEVGIGAGLVLDGELYRGVRGWSGEIGHVTVYPDGRPCRCGARGCLEQYAGQEALTGDEPLAAAALGIALAAVVNLLDVPVIVLGGAYAPLFTELRAGIEEELTRRVLTSGLAPVALRPAALGADAAMRGAADTVIRAVRDDPAAWLRR
>NC_017093.1|WP_014441152.1|1107409_1108594_+|xylose-isomerase
MSVQATREDKFSFGLWTVGWQARDAFGDATRTALDPVEAVHKLAEIGAYGITFHDDDLVPFGSDAQTRDGIIAGFKKALDETGLIVPMVTTNLFTHPVFKDGGFTSNDRSVRRYAIRKVLRQMDLGAELGAKTLVLWGGREGAEYDSAKDVSAALDRYREALNLLAQYSEDRGYGLRFAIEPKPNEPRGDILLPTAGHAIAFVQELERPELFGINPETGHEQMSNLNFTQGIAQALWHKKLFHIDLNGQHGPKFDQDLVFGHGDLLNAFSLVDLLENGPDGAPAYDGPRHFDYKPSRTEDYDGVWESAKANIRMYLLLKERAKAFRADPEVQEALAASKVAELKTPTLNPGEGYAELLADRSAFEDYDADAVGAKGFGFVKLNQLAIEHLLGAR

Crispr_ID: NC_017093_4

• CRISPR_ID: NC_017093_4
• CRISPR_location: 1298779-1298873
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_4

Consensus_repeat	Method
TGCCGGGCCGTAGCTCAGGCATGTGATCAAG	CRISPRCasFinder

spacers of NC_017093_4

>4.1|1298810|33|NC_017093|CRISPRCasFinder
GGGTGGATGGCCGCGCTGGCCTACGGCTGGGGG

CRISPR arrays and Neighbor proteins around NC_017093_4

CRISPR arrays

The CRISPR arrays of NC_017093_4

>merge|NC_017093|4|1298779-1298873|CRISPRCasFinder
TGCCGGGCCGTAGCTCAGGCATGTGATCAAGGGGTGGATGGCCGCGCTGGCCTACGGCTGGGGGTGCCGGGCCGTAGCTCCGGCATGTGATCAAG

>NC_017093|4|4|1298779-1298873|CRISPRCasFinder
TGCCGGGCCGTAGCTCAGGCATGTGATCAAG	GGGTGGATGGCCGCGCTGGCCTACGGCTGGGGG
TGCCGGGCCGTAGCTCCGGCATGTGATCAAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_014441338.1|1301204_1301585_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014441339.1|1301835_1302192_+|VOC-family-protein	unknown	unknown	gnl|CDD|380093
NC_017093.1|WP_014441332.1|1295518_1296256_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_017093.1|WP_014441343.1|1305850_1306774_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_017093.1|WP_014441341.1|1303450_1305313_+|DNA-primase	unknown	unknown	gnl|CDD|235551
NC_017093.1|WP_157435260.1|1296324_1297389_-|MFS-transporter	unknown	unknown	gnl|CDD|340883
NC_017093.1|WP_014441330.1|1294053_1294308_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014441334.1|1297505_1298585_-|DUF2786-domain-containing-protein	unknown	unknown	gnl|CDD|378525
NC_017093.1|WP_014441335.1|1299051_1299423_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014441325.1|1289911_1290253_+|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl|CDD|367760
NC_017093.1|WP_014441340.1|1302201_1303416_+|deoxyguanosinetriphosphate-triphosphohydrolase	unknown	unknown	gnl|CDD|235098
NC_017093.1|WP_014441328.1|1292285_1292801_-|XdhC-family-protein	unknown	unknown	gnl|CDD|379212
NC_017093.1|WP_014441336.1|1299478_1299967_-|roadblock/LC7-domain-containing-protein	unknown	unknown	gnl|CDD|224929
NC_017093.1|WP_014441327.1|1290835_1292215_+|glycine--tRNA-ligase	unknown	unknown	gnl|CDD|235240
NC_017093.1|WP_014441329.1|1292853_1293987_+|tRNA-dihydrouridine-synthase-DusB	unknown	unknown	gnl|CDD|129820
NC_017093.1|WP_014441331.1|1294304_1295522_+|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NC_017093.1|WP_014441337.1|1300021_1301167_-|DUF4388-domain-containing-protein	unknown	unknown	gnl|CDD|237874
NC_017093.1|WP_014441344.1|1306775_1307525_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|130358
NC_017093.1|WP_014441342.1|1305309_1305840_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014441326.1|1290269_1290767_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_014441332.1|1295518_1296256_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	9.31443e-68
NC_017093.1|WP_014441343.1|1305850_1306774_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	7.04531e-104
NC_017093.1|WP_014441341.1|1303450_1305313_+|DNA-primase	gnl|CDD|235551	PRK05667, dnaG, DNA primase; Validated.	0
NC_017093.1|WP_157435260.1|1296324_1297389_-|MFS-transporter	gnl|CDD|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.06286e-13
NC_017093.1|WP_014441339.1|1301835_1302192_+|VOC-family-protein	gnl|CDD|380093	pfam18029, Glyoxalase_6, Glyoxalase-like domain. This entry comprises a diverse set of domains related to the Glyoxalase domain. The exact specificity of these proteins is uncertain.	1.23806e-30
NC_017093.1|WP_014441334.1|1297505_1298585_-|DUF2786-domain-containing-protein	gnl|CDD|378525	pfam10979, DUF2786, Protein of unknown function (DUF2786). This family of proteins has no known function.	9.9956e-13
NC_017093.1|WP_014441325.1|1289911_1290253_+|antibiotic-biosynthesis-monooxygenase	gnl|CDD|367760	pfam03992, ABM, Antibiotic biosynthesis monooxygenase. This domain is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species. It's occurrence as a repeat in Streptomyces coelicolor SCO1909 is suggestive that the other proteins function as multimers. There is also a conserved histidine which is likely to be an active site residue.	6.08703e-07
NC_017093.1|WP_014441340.1|1302201_1303416_+|deoxyguanosinetriphosphate-triphosphohydrolase	gnl|CDD|235098	PRK03007, PRK03007, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional.	0
NC_017093.1|WP_014441328.1|1292285_1292801_-|XdhC-family-protein	gnl|CDD|379212	pfam13478, XdhC_C, XdhC Rossmann domain. This entry is the rossmann domain found in the Xanthine dehydrogenase accessory protein.	2.00335e-30
NC_017093.1|WP_014441336.1|1299478_1299967_-|roadblock/LC7-domain-containing-protein	gnl|CDD|224929	COG2018, COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid [General function prediction only].	2.56563e-19
NC_017093.1|WP_014441327.1|1290835_1292215_+|glycine--tRNA-ligase	gnl|CDD|235240	PRK04173, PRK04173, glycyl-tRNA synthetase; Provisional.	0
NC_017093.1|WP_014441329.1|1292853_1293987_+|tRNA-dihydrouridine-synthase-DusB	gnl|CDD|129820	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family. This model represents one branch of COG0042 (Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family). This branch includes NifR3 itself, from Rhodobacter capsulatus. It excludes a broadly distributed but more sparsely populated subfamily that contains sll0926 from Synechocystis PCC6803, HI0634 from Haemophilus influenzae, and BB0225 from Borrelia burgdorferi. It also excludes a shorter and more distant archaeal subfamily.The function of nifR3, a member of this family, is unknown, but it is found in an operon with nitrogen-sensing two component regulators in Rhodobacter capsulatus.Members of this family show a distant relationship to alpha/beta (TIM) barrel enzymes such as dihydroorotate dehydrogenase and glycolate oxidase. [Unknown function, General].	5.36476e-131
NC_017093.1|WP_014441331.1|1294304_1295522_+|two-component-sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.29454e-37
NC_017093.1|WP_014441337.1|1300021_1301167_-|DUF4388-domain-containing-protein	gnl|CDD|237874	PRK14971, PRK14971, DNA polymerase III subunit gamma/tau.	1.27284e-08
NC_017093.1|WP_014441344.1|1306775_1307525_+|ABC-transporter-permease	gnl|CDD|130358	TIGR01291, Nodulation_protein_J, ABC-2 type transporter, NodJ family. Nearly all members of this subfamily are NodJ which, together with NodI (TIGR01288), acts to export a variety of modified carbohydrate molecules as signals to plant hosts to establish root nodules. The seed alignment includes a highly divergent member from Azorhizobium caulinodans that is, nonetheless, associated with nodulation. This model is designated as subfamily in part because not all sequences derived from the last common ancestral sequence of Rhizobium sp. and Azorhizobium caulinodans NodJ are necessarily nodulation proteins. [Cellular processes, Other, Transport and binding proteins, Other].	1.41512e-20

Protein sequences

>NC_017093.1|WP_014441334.1|1297505_1298585_-|DUF2786-domain-containing-protein
MTAREIVDRVRAGNLDHETALDMLTGAPAAEVDSALQTTLETEFDRLFRNGWQPAELHRAVARRGNPIQADLAAEASRDFQKSRTPVDPRWRSQADSLPLSQDRRRPDRIAVIDAKLTLLTELRQLPAIEILIPPPGTPLTTVPHHSDQRILDRVRALLAKAEATDFAAEAEAYSAKAQELITRYRIEEITAPAVDVVPFARRIGVDHPYENEKASLLDAVSRANNCRCVWTPELGFSTIFGFDADIDAVELLYTSLLVQANRAMTRDEPAKGKARVKAFRRSFLVAYAIRIGQRLRETAEREMAGHSDLLPVLRNRDIQVREAMNKVFPTTVRARGSRVDSLEGWESGRAAADEAQLR
>NC_017093.1|WP_157435260.1|1296324_1297389_-|MFS-transporter
MADAGLTTAEISSLFAIWSVVSFACEIPAGALADVWSRKRLYAIGELTTATGFTLWLIWPSYPGFAICFALWGLGGAFSSGTLESLVYDKLGDSTAYAQVIGRADTIALLGMLAATLLAAPAYATGGYLLVGIISIATVALGGLLALRLPDYEGTEDDSDESSTGGYLTVLRDGLTEVLGKAGTVGRAVVVAAAVPGFSALDEYLPLLSRDKDATTSTVPLLFALTALSMAAGSALAGRVSPGSARPLSLAVSLAAVTLAAGALIPHLAGMVLVSAAFGLLQFAMVHAESRLQGEMSGRSRTTVLSVAGFGAELCAVLLYAGFALPLELPVLFALAAIPLLATALLTARPHPAC
>NC_017093.1|WP_014441332.1|1295518_1296256_+|response-regulator-transcription-factor
MTGSGALRVLVVDDQQLVREGLTALLELTDGVTVVGSAGDGERAIEMIADHRPDVVLMDLRMPVLDGVAATARARERFPEVAVVVLTTYADDESIAGALAAGARGYLTKDAGRAEIAMALRAAAAGNSLFAPEVSARLAEAMRRPAEVSEADRGRSSDQSGRLPDRLPGRLSDGQPGRLPDGLTRREAEVLGRIGQGRTNAEIAAELFVAEATIKTHINNAFAKIGVRNRAEATRYALRHGLTPG
>NC_017093.1|WP_014441331.1|1294304_1295522_+|two-component-sensor-histidine-kinase
MTLREGVRRLRADDPETGILVRIVLSALLIWAFVTAGPAGPGVRPVLAAALACWFVFVAGDRRLPRLARVALAMAAVLPAVAASQPDDASSLLYLYAALFTFVLLPRTPMWAILSLTAVVLTVLLTGLWIAGRGTAAMLTQPALIAVLVLFSLHRREYRLRAEQTALLLEQITQTRAAQARAAALDERARIARELHDVLAHSLGALGVQLEVAEIQLTERGDVDGAAARIRQARELAADGLAEARSAVRALRADVPPLPQALHDLVTRHEADHGVAVTLRVVSERRALSPGAEVSLLRIAREALTNAARHAPGAPVTVTLDYADPAVARLTVRNPVPGASPRAVGRIPAIGGTGGLGLIGARERIALVGGTLKTGPADGEWQVIAEAPSPGAQGDPWGADEGTAA
>NC_017093.1|WP_014441330.1|1294053_1294308_+|hypothetical-protein
MGMNENRDKGRRAVNYVVTGKADGNHGTRLAGEVIGRVLGRDGGRITGRVVVAILVVLGVAGLAFVAYRLLMIDLILNLVGERG
>NC_017093.1|WP_014441329.1|1292853_1293987_+|tRNA-dihydrouridine-synthase-DusB
MTAPLLLGDHAVNPPVVLAPMAGITNVAFRRLCREQGGGVYVCEMITTRALVERIPKTLKMITFAEDEGFRSLQLYGVDPDVTAAAVRMVGEDNLADHIDLNFGCPVPKVTRRGGGSALPWRRRLFARIVQQAVDAAKPFGIPVTIKMRKGIDDDHLTYVEAGLAAQDAGVAAVALHARTAEQRYSGKADWEAIATLKQALDVPVLGNGDIWEGSDALRMVEQTGVDGVVVGRGCLGRPWLFADLEAAFTQGAGYRPVLPTLGEVAKILARHAQLLVEALEDEKHGCADFRKHVAWYLKGFPVGGELRRSLAMISSLAELDDLLAKLDPAVPFPAEALGQPRGRVNAPGKVSLPHGWLDSRDDDTVPEGAETEESGG
>NC_017093.1|WP_014441328.1|1292285_1292801_-|XdhC-family-protein
MWRKSGRVGRVGDSELSPRRLVAVFESPVSEALQRFAVELGFHTVLVEPDPTRLSGTPRPHGDTFVADLVAAGIDEHTDVVLTDHHRAEIGAVLQEALAGKSRWIGIVGNPRSEGPHVEALRELGVPAEEIARVHRPIGLNIGSRTGPEIALAILAGLIADRNDRPGGFHF
>NC_017093.1|WP_014441327.1|1290835_1292215_+|glycine--tRNA-ligase
MPADRIDAVVSLAKRRGFVFPSSEIYGGTRSAWDYGPLGVELKENVRRQWWRTMVQQRDDIVGLDSAVILSRDVWAASGHLDAFVDPLTECQSCHKRFRADHLEEAYEAKHGSLPASLKDLNCPNCGNKGTFTEPKMFNGLMKTYLGPTESAEGLHYLRPETAQGIFVNYNNVATAARKKPPFGIAQIGKSFRNEITPGNFIFRTREFEQMEMEFFVVPGSDEEWHEYWLQQRWDWYRDLGLSESNLRFFEHPKEKLSHYSKRTVDIEYRFQFGGTEFAELEGIANRTDFDLSTHSKHSGVDLSYFDQEKGERWVPYVIEPAAGLTRAVLAFLLEAYDEDEAPNTKGGVDKRTVMRFDPRLAPVKVAVLPLSRNPELSPKARELSANLRKRWIVEFDDSQAIGRRYRRQDEIGTPFCVTVDFDTLTDNAVTVRDRDTMKQERVSLDQIEDYLIKRLPGC
>NC_017093.1|WP_014441326.1|1290269_1290767_+|hypothetical-protein
MSTAPHYVPPPPPGPGVHPPFPAPPVEGRGRRVGVSLGITGGVLLLVCGGGAAAVAGLTAAMDDALNEQVDVVVGRYVQAVQNRDFARSYDLLCPAAQRAESESAYTSRLSATEPFSAYQIGDLDLVYASVPVQLTYPDGRTETVEAELSQNTSTGAFEVCDLGE
>NC_017093.1|WP_014441325.1|1289911_1290253_+|antibiotic-biosynthesis-monooxygenase
MLVLNRFHVPPETQDGFVERAHAALAALADSPGYRSGRLARALEDPAAWTLVTEWESVGAYRRALGRFEVKMHATPLLAETLDEPSAFETLASAAPGEAVVVTASDRAAEPWR
>NC_017093.1|WP_014441335.1|1299051_1299423_-|hypothetical-protein
MPDMDTALKEIMEIDGCIGVALVDHTSGMALGTLGGGKELDLTVAAAGNTDVVRAKLRAMEMLNLSEKIEDILITLDTQYHMIRPLTSRSGKGLFLYVALRRDRANLAMSRHRLRSIENDLDV
>NC_017093.1|WP_014441336.1|1299478_1299967_-|roadblock/LC7-domain-containing-protein
MTVDPAVLEELGRLRSKVPELSGSVLATADGLVVAHDSHGLEPDTLAALAAAHLALARRFAHAVNHGELRESVVECDGGYITSYTAGPNALLTVVTSGDANLAMVHLEARRCVRRLIKIMALETAPQLRPQIPTQSGPPTPLARRTPMATLSNVSRRRQATG
>NC_017093.1|WP_014441337.1|1300021_1301167_-|DUF4388-domain-containing-protein
MASTKTASPGNLLTQVAGERQTGALVVSGQPGGAVYVFEGRIIYAESPSAPGVGEMLTSSGRLAGRTWQSALDLGTSTARVGRILVEQGHLTQGELELCVLGSTYDAAYFVLAQPAASVEFLPGATHWLGAIVHIDAAAVGREVRRRVKLLDDIFPNPRIDVAPVIPVTRAPRERITLTAPQWELLVHADGQRTPADLALLLGRAGYATIQELRRLAALGMIELPRVRVSDSPELVRLPHPRGAAVPIDRAPPASSRAAASPQASASPQASPSPQASASPQAPAPARNPASSPVPVSAPPVPVINGSEPAAARAAPPEPDPPPAPPPGDHNAGLNRAPRLARRKPGAKLPKEIASAENPPVHQGTDEVLLKRIRTALRALR
>NC_017093.1|WP_014441338.1|1301204_1301585_-|hypothetical-protein
MPGVDHCLQEAMTIPGAVGASIVDYTTGFPVATTGAAPNSDHEAAAAGTAEVVQAANSRSLFVSAVPHDLLEDLIITTAGGYHLLRLVQTEFDSRLVLYVWLDRVRGNLAVARRKMQRLADELVTT
>NC_017093.1|WP_014441339.1|1301835_1302192_+|VOC-family-protein
MPSRWEQVVVDAEDPPRLARWWAEALGYVLVNEEPGEVEIRRTRHELPGLLFTPVSDPKRGKNRLHIDLRPDDQEAEVERLVGMGARPVDIGQGNPGWVVLADPEGNEFCVLGARPAA
>NC_017093.1|WP_014441340.1|1302201_1303416_+|deoxyguanosinetriphosphate-triphosphohydrolase
MTPADSQRWAPEPAKDSGYGRTPYQRDRARVLHSAGFRRLAAKTQVHTAGSDDFLRTRLTHSLEVAQISREMGARLGCDPDVVDVAGLAHDLGHPPFGHNGEAALDEVARACGGFEGNAQTLRVLTRLEAKVPGAGLNLTRATLDACSKYPWFRKEGYRKFGVYADDRPVFAWLRDGRDDERRCLEAQVMDWADDVAYSVHDVEDGVHGGYLSLEPLLRDADERAALCRDVAATYSQESPDELLAALDQLLADPAVSAVAGYDGGYAAQVALKRMTSVLTGRFVASAVGATHSRFGTDPMRRYDADLIVPRTVRNQCALLKGMAFRYVMRTRAAEDWYAEQRVILVELVAALTRTPERLDPLFGPLHATATDDAAALRVIIDQVASLTDHAAVAWHKSLVPARR
>NC_017093.1|WP_014441341.1|1303450_1305313_+|DNA-primase
MYAVAGRVKDEDIALVRDRSSIVDVISETVTLRSAGGGNLKGLCPFHDEKTPSFNVSPARNVYFCHGCGQGGDAIKFLMDAEHLSFIESVERLASKAGIQLRYDTDGPGVSTPRPQTGQRQRLLAAHADATAFYRDQLGSPGARKAREFLAQRGFGRDAAEKYGCGFAPDSWDALSKHLRLKGYTAEELTAAGLAKPARSGSLIDRFRRRLLWPIKDLSGDVIGFGARKLFDDDDGPKYLNTPETPIYKKSHVLYGIDHAKREIAKRGRAVIVEGYTDVMACHEAGEPTAVATCGTAFGLDHIQVLRRLLMDSDSFTGEIIYTFDGDAAGQKAALRAFEEDQRFVGRTFIAVSPDNMDPCELRLAKGDLAVRDMIAGREPLVDFALRQTLAKYDLDSVEGRVEAMRRAAPLVAKIKDREKRPEYARKLAGDLGMDLEPVQRAVANAARSASADPQPQRAASPADSPQRMVEREALKIALQEPVLAGPMFDALGAENYADPVLASVREAVSEAGGAQAATGGAVWIEKVRDCCADMGGQMLVSELAVEPLYVDGPVDPRYVQVTLARLQGAALATRIRDLKSKVQRLNPVANKDQYLALAGELFSLEQQARALRDQAAGGL
>NC_017093.1|WP_014441342.1|1305309_1305840_+|hypothetical-protein
MKLFRRRPRLPADARPPLDPAERVVAWCPVSPADSGVLVATNHGIWLPGAAQRLGWHEIHKVAWSGRELRIIPAVVESVREGYTVLADGPAVTFLLLEPGEVPDQVRARVTRSVAYTTHHPLPEGAVRVVGRRISGRDGLSWAVRYDVGTPVEHDEVITATDELVGAARETVAPPL
>NC_017093.1|WP_014441343.1|1305850_1306774_+|ABC-transporter-ATP-binding-protein
MSSLIHARGLIKRFESFTAVDGIDVDVQAGEAFGFLGPNGAGKSSTMRMIGCVSPPTEGELRILGMDPRRDGPAIRARLGVCPQLDNLDIELTVRENLTTYARFFGIPRRVARARADELLEFVQLSERADSKVEPLSGGMKRRLTIARALVNEPDLVLLDEPTTGLDPQARHLVWERLFRLKQQGVTLVLTTHYMDEAEQLCDRLVVMDGGRIVAEGSPRALIEQYSTREVVELRFPAEDQGTYAGKLAGIADRIEVLPDRVLLYVSDGDDALAEVHRRSLSPASALVRRSSLEDVFLHLTGRTLVD
>NC_017093.1|WP_014441344.1|1306775_1307525_+|ABC-transporter-permease
MTHVFEYHLVNYRRTWRSSALSTLLLPLLTMVGFGLGVGGYVQGGIAGVPYLDWMVPGLIASTAMQAAIGESTWPVLSYFEWLKVYFAQAAAPLRVADILGGHLAFMMFRVLLSVTAFVLIAALFGTLHSVWALAVLPISVLTGLAVAAPVTAYSASVSSDSYLAILVRFAVLPMSLFSGVFFPLDSLHPVLRAVAWALPLSHGVDLSRTATLGLGVGWADLGQVLYLLLWCAVGWFLALRRFGRRLVV

Crispr_ID: NC_017093_5

• CRISPR_ID: NC_017093_5
• CRISPR_location: 1713698-1713770
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NC_017093_5

Consensus_repeat	Method
GCTTGTCGTGGCTGCGCGCCTTG	CRISPRCasFinder

spacers of NC_017093_5

>5.1|1713721|27|NC_017093|CRISPRCasFinder
CCCGCCGGGCGGCTTGGCTGGCGGGCG

CRISPR arrays and Neighbor proteins around NC_017093_5

CRISPR arrays

The CRISPR arrays of NC_017093_5

>merge|NC_017093|5|1713698-1713770|CRISPRCasFinder
GCTTGTCGTGGCTGCGCGCCTTGCCCGCCGGGCGGCTTGGCTGGCGGGCGGCTTGTCGTGGCTGCGCGCCTTG

>NC_017093|5|5|1713698-1713770|CRISPRCasFinder
GCTTGTCGTGGCTGCGCGCCTTG	CCCGCCGGGCGGCTTGGCTGGCGGGCG
GCTTGTCGTGGCTGCGCGCCTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_014441699.1|1705575_1708269_+|DNA-polymerase-I	unknown	unknown	gnl|CDD|235591
NC_017093.1|WP_014441711.1|1721794_1722217_+|50S-ribosomal-protein-L11	unknown	unknown	gnl|CDD|234661
NC_017093.1|WP_014441706.1|1714132_1716250_+|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl|CDD|235395
NC_017093.1|WP_014441709.1|1718778_1720641_-|translational-GTPase-TypA	unknown	unknown	gnl|CDD|273597
NC_017093.1|WP_014441695.1|1700953_1701946_+|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|119323
NC_017093.1|WP_014441710.1|1720791_1721610_+|lytic-transglycosylase-domain-containing-protein	unknown	unknown	gnl|CDD|381594
NC_017093.1|WP_014441712.1|1722273_1722903_-|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl|CDD|132928
NC_017093.1|WP_014441702.1|1709063_1709282_-|DUF2945-domain-containing-protein	unknown	unknown	gnl|CDD|378576
NC_017093.1|WP_014441697.1|1702989_1703772_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213191
NC_017093.1|WP_014441698.1|1704095_1705364_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380569
NC_017093.1|WP_041830611.1|1716637_1716967_-|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl|CDD|367760
NC_017093.1|WP_014441708.1|1717604_1718600_+|TerC-family-protein	unknown	unknown	gnl|CDD|274743
NC_017093.1|WP_083888589.1|1710711_1712343_+|30S-ribosomal-protein-S1	unknown	unknown	gnl|CDD|236126
NC_017093.1|WP_041829618.1|1723531_1723873_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014441703.1|1709688_1710486_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_017093.1|WP_014441715.1|1724253_1724763_+|SigE-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|132028
NC_017093.1|WP_014441705.1|1712491_1713676_+|dephospho-CoA-kinase	unknown	unknown	gnl|CDD|179560
NC_017093.1|WP_041829617.1|1708750_1709071_-|DUF3140-domain-containing-protein	unknown	unknown	gnl|CDD|371477
NC_017093.1|WP_083888791.1|1708497_1708746_+|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NC_017093.1|WP_014441713.1|1723142_1723535_-|roadblock/LC7-domain-containing-protein	unknown	unknown	gnl|CDD|224929

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017093.1|WP_083888791.1|1708497_1708746_+|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	1.5e-19	65.3	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_014441699.1|1705575_1708269_+|DNA-polymerase-I	gnl|CDD|235591	PRK05755, PRK05755, DNA polymerase I; Provisional.	0
NC_017093.1|WP_014441711.1|1721794_1722217_+|50S-ribosomal-protein-L11	gnl|CDD|234661	PRK00140, rplK, 50S ribosomal protein L11; Validated.	4.13875e-48
NC_017093.1|WP_014441706.1|1714132_1716250_+|excinuclease-ABC-subunit-UvrB	gnl|CDD|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NC_017093.1|WP_014441709.1|1718778_1720641_-|translational-GTPase-TypA	gnl|CDD|273597	TIGR01394, GTP-binding_protein_TypA/BipA_homolog, GTP-binding protein TypA/BipA. This bacterial (and Arabidopsis) protein, termed TypA or BipA, a GTP-binding protein, is phosphorylated on a tyrosine residue under some cellular conditions. Mutants show altered regulation of some pathways, but the precise function is unknown. [Regulatory functions, Other, Cellular processes, Adaptations to atypical conditions, Protein synthesis, Translation factors].	0
NC_017093.1|WP_014441695.1|1700953_1701946_+|branched-chain-amino-acid-ABC-transporter-permease	gnl|CDD|119323	cd06581, TM_PBP1_LivM_like, Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivM forms a heterodimer with another TM, LivH, to generate the transmembrane pore. LivH is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	5.04463e-61
NC_017093.1|WP_014441710.1|1720791_1721610_+|lytic-transglycosylase-domain-containing-protein	gnl|CDD|381594	cd00254, LT-like, lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.	4.05876e-12
NC_017093.1|WP_014441712.1|1722273_1722903_-|ATP-dependent-Clp-protease-proteolytic-subunit	gnl|CDD|132928	cd07017, S14_ClpP_2, Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease. Clp protease (caseinolytic protease; ClpP; Peptidase S14) is a highly conserved serine protease present throughout in bacteria and eukaryota, but seems to be absent in archaea, mollicutes and some fungi. Clp proteases are involved in a number of cellular processes such as degradation of misfolded proteins, regulation of short-lived proteins and housekeeping removal of dysfunctional proteins. They are also implicated in the control of cell growth, targeting DNA-binding protein from starved cells. ClpP has also been linked to the tight regulation of virulence genes in the pathogens Listeria monocytogenes and Salmonella typhimurium. This enzyme belong to the family of ATP-dependent proteases; the functional Clp protease is comprised of two components: a proteolytic component and one of several regulatory ATPase components, both of which are required for effective levels of protease activity in the presence of ATP, although the proteolytic subunit alone does possess some catalytic activity. Active site consists of the triad Ser, His and Asp; some members have lost all of these active site residues and are therefore inactive, while others may have one or two large insertions. ClpP seems to prefer hydrophobic or non-polar residues at P1 or P1' positions in its substrate. The protease exists as a tetradecamer made up of two heptameric rings stacked back-to-back such that the catalytic triad of each subunit is located at the interface between three monomers, thus making oligomerization essential for function.	1.70821e-35
NC_017093.1|WP_014441702.1|1709063_1709282_-|DUF2945-domain-containing-protein	gnl|CDD|378576	pfam11160, DUF2945, Protein of unknown function (DUF2945). This family of proteins has no known function.	1.87626e-17
NC_017093.1|WP_014441697.1|1702989_1703772_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213191	cd03224, ABC_TM1139_LivF_branched, ATP-binding cassette domain of branched-chain amino acid transporter. LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.	8.3592e-100
NC_017093.1|WP_014441698.1|1704095_1705364_-|ABC-transporter-substrate-binding-protein	gnl|CDD|380569	cd06346, PBP1_ABC_ligand_binding-like, type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.	6.56797e-88
NC_017093.1|WP_041830611.1|1716637_1716967_-|antibiotic-biosynthesis-monooxygenase	gnl|CDD|367760	pfam03992, ABM, Antibiotic biosynthesis monooxygenase. This domain is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species. It's occurrence as a repeat in Streptomyces coelicolor SCO1909 is suggestive that the other proteins function as multimers. There is also a conserved histidine which is likely to be an active site residue.	6.14864e-10
NC_017093.1|WP_014441708.1|1717604_1718600_+|TerC-family-protein	gnl|CDD|274743	TIGR03718, R_switched_Alx, integral membrane protein, TerC family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family often are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains TerC itself from Alcaligenes sp. plasmid IncHI2 pMER610 and from Proteus mirabilis. It also contains the alkaline-inducible E. coli protein Alx, which unlike the two TerC examples is preceded by a yybP-ykoY leader.	1.67486e-136
NC_017093.1|WP_083888589.1|1710711_1712343_+|30S-ribosomal-protein-S1	gnl|CDD|236126	PRK07899, rpsA, 30S ribosomal protein S1; Reviewed.	0
NC_017093.1|WP_014441703.1|1709688_1710486_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.48663e-22
NC_017093.1|WP_014441715.1|1724253_1724763_+|SigE-family-RNA-polymerase-sigma-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	4.43602e-39
NC_017093.1|WP_014441705.1|1712491_1713676_+|dephospho-CoA-kinase	gnl|CDD|179560	PRK03333, coaE, dephospho-CoA kinase/protein folding accessory domain-containing protein; Provisional.	1.14761e-168
NC_017093.1|WP_041829617.1|1708750_1709071_-|DUF3140-domain-containing-protein	gnl|CDD|371477	pfam11338, DUF3140, Protein of unknown function (DUF3140). Some members in this family of proteins are annotated as DNA binding proteins. No function is currently known.	1.01267e-47
NC_017093.1|WP_083888791.1|1708497_1708746_+|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.30664e-19
NC_017093.1|WP_014441713.1|1723142_1723535_-|roadblock/LC7-domain-containing-protein	gnl|CDD|224929	COG2018, COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid [General function prediction only].	1.25041e-11

Protein sequences

>NC_017093.1|WP_014441705.1|1712491_1713676_+|dephospho-CoA-kinase
MLRVGLTGGIGAGKSAVAQRFAERGAVIIDADVLSREVVEAGTEGLAEIVEAFGAGVLTAEGTLDRPALGAKVFGDEAARRTLEKIIHPRVRARTAELTLGAARDAIVVNDVPLLVEAGLAPSYHLVVVVLADRDLRVQRLTQLRGMSAAEAAARIGAQTDDEHRRATADAIVTNDADLATLHARVDELWRDRIVEFERNLRMGRSAPRNQNLRIVPFDPEWPARADRLIARIRHGLGDHIEVHHIGSTAVPGLPAKGVIDLMLSVRTLDEADALADRLAEIGFPRRPGEWFDNTRKVPGSTWPKRLHGCADPGYEVNLHVRVAGSPGWRFALLMRDHLRAVPEARDAYAAARAAWAVRFEDRAGYAEAKEPWFAQEAQAADDWALQTGWQPPV
>NC_017093.1|WP_083888589.1|1710711_1712343_+|30S-ribosomal-protein-S1
MANDQTAPQLGRLPRSCRCRRQFRRARETPRIHPFGATVHMTSSIEATSSANKVTVDDLGSEEAFLAAIDETIKYFNDGDIVEGTVVKVDRDEVLLDIGYKTEGVIPSRELSIKHDVDPAEVVSVGDHIEALVLTKEDKEGRLILSKKRAQYERAWGTIEKIKEDDGVVRGSVIEVVKGGLILDIGLRGFLPASLVEMRRVRDLQPYVGRELEAKIIELDKNRNNVVLSRRAWLEQTQSEVRTEFLNKLQKGQVRKGVVSSIVNFGAFVDLGGVDGLVHVSELSWKHIDHPSEVVEVGQEVEVEVLDVDLDRERVSLSLKATQEDPWRQFARTHAINQIVPGKVTKLVPFGAFVRVDDGIEGLVHISELAERHVELPEQVVQVGSDVLVKVIDIDLERRRISLSLKQANENFVEGEEHFDPTLYGMAATYDNEGNYIYPEGFDPETGEWLEGFDKQRETWEKQYADARERWEAHTKQVQASREADAEAALNPAPAGGVTSSSSSTSSSTSSSAPARSNEEPAGTLATDEALAALREKLAGGKS
>NC_017093.1|WP_014441703.1|1709688_1710486_-|class-I-SAM-dependent-methyltransferase
MTEIATRKTVSETEARRANRAWWDLDADDYQDEHGNFLGDVDFVWCPERLREAEAGLLGPVPGKKILELGAGAAAASRWLRVQGASPVALDLSAGMLRHASEAAGRSGVHVPLVQADALALPFADDAFDIVCTAFGAIPFVADSAAAMREVARVLRPGGSWVFSVTHPMRWAFWDEPGEDGLVVRNSYFDRSPYVERDEQGRVTYLEQHRTLGDRIRELVGAGFVLRDLVEPEWPEGHQQIWGQWSPLRGRLFPGTAIFVCDLPA
>NC_017093.1|WP_014441702.1|1709063_1709282_-|DUF2945-domain-containing-protein
MTDGEKSLKKGDKVTWRSHGEDVHGTVQQKITKRTEAAGRTVAASPDDPQYRVKSDKSGRDAVHKPGALRHD
>NC_017093.1|WP_041829617.1|1708750_1709071_-|DUF3140-domain-containing-protein
MTDVYAEFRDAVNMTAAELRTWLDTDESQQVGQKSSAKAESVGHDSGRKIVAILGKKKADLTGGDEEHMRKVVGYVHRHTAQRPDGDVRETPWRYSLMNWGHDPLK
>NC_017093.1|WP_083888791.1|1708497_1708746_+|winged-helix-turn-helix-transcriptional-regulator
MFKALGDPVRLRLLSMIASAPEGEICVCDLSGEFPLTGPTISHHLRILREAGLVDCDRRGTWVYYRSVPDTLTLLADVLDVT
>NC_017093.1|WP_014441699.1|1705575_1708269_+|DNA-polymerase-I
MSDDAKTPRLLLLDGHSLAYRAYFALPVENFSTATGQPTNAVFGFTSMLINMLRDEKPTHIVVAFDLSRRSFRTEKYADYKAGRSETPQPFQGQVSLIKEVLEALRIPVVEKENYEADDVIATLATQARESGMEVVISTGDRDAFQLANEHVTILYPVRGVSEVWRMTPEAIEAKYFVPPARYRDKAALVGETSDNLSGVPGVGDKTAAKWIKEFDGLDGIIANVDKIKGKAGESLRAHLADVMRNYDLNRLVCDLELPLRPEDVRWHGWDREAVHSVFDALEFRVLRERLYSYLEAVEPEAESGFDVDGSILPTGGVSAWLREFAGTDPVGVAVIGRFGRGAGELTGVAVATGSGPAAWFDPSTLDEDDERAVAAWLAEPSRPKVLHDAKPALLAFQAHGWQLAGVTTDTALAAYLAKPDQRAYDLNDLALRYLKRELRVDEPSDGQLTLDGLGGDDGAGEMNLMLRARATLDLAEVLTTELSRDGGESMRLLADVEQPLSVVLAAMERLGIAADTDYLSELESHFAAEVKAAQQAAHEVVGREFNLGSPKQLQEILFVERNLPKTKKIKSGYTTDADALQSLFAQTGDPVLAHLLRHRDVAKLKSTVDGLLKSVSDDGRIHTTFNQTVAATGRLSSTDPNLQNIPIRTEEGRRIRRAFVVGPGLEQLMTADYSQIEMRIMAHLSGDDALIAAFNSGADFHAATASSVFHVGLDEVTPDQRRKIKAMNYGLAYGLSAFGLSNQLTISTEEARGLMEEYFERFGGVRDYLQAVVTQAGKDGYTATILGRRRYLPDLLSDNRQRREMAQRMALNAPIQGSAADIIKIAMLRVDEALRDSGLASKMLLQVHDELVFEVANGEREQLEELVRREMGGAYPLSVPLEVSVGVGRDWNGADH
>NC_017093.1|WP_014441698.1|1704095_1705364_-|ABC-transporter-substrate-binding-protein
MIRRNFAWRSVAVLGAACLALGACSNDGDEPESGSSSAPAAAAGDGVLKIGTLLPQTGSLAFLGPPEFAGVDLAAKEINAAGGVLGKDVVVSDTDSGDTTTDIASQSVNKLLAEKADVIIGAASSSVSLSVIDKITGAGVVQISPANTSDQFTTYNDKGLYYRTAPPDVLQGRVLGDLVVADGNATVGMMVLQDAYGTGLAKSARAAIESGGGQVVAEEVYDPKAADFSAEIGKIKQANPSAIILIGFDETKKIVPKLVEAGLTAKSKKWYFVDGNLSNYGSEFPNGTFEGAKGTLPGAKAGEDFQKKLLEVDPALKDFSYAAESYDAAILTALAAEAAKSDAPGDYSKQLSAVSKDGEKCTTFQQCKEALAAGKDIDYDGVSGPISWNDAGDPAEATIGIYQYGPDNTYKNVSYQNGKIDG
>NC_017093.1|WP_014441697.1|1702989_1703772_+|ABC-transporter-ATP-binding-protein
MSDAVSSNEVEGRDEHLTAAEGALVRVDDVTAGYLPGVNILNGCDLYAKEGELVGIIGPNGAGKSTLLKSLFGLVTIRSGEVTLRGEKITNVKANKLVAKGIGFVPQTNNVFGTLTIEENLEMGTFLRPKRFKERFEFVAGLFPALGTRRKQRAGSLSGGERQMVAMGRALMMEPSVLLLDEPSAGLSPAMQDEVFFRTKQINDTGVTVIMVEQNARRCLQICNRGYVLDQGRNAYTASGRDLIHDPKVIELYLGTLARA
>NC_017093.1|WP_014441695.1|1700953_1701946_+|branched-chain-amino-acid-ABC-transporter-permease
MSWDIILGVSLESLINATMIAYALAAIGLNVHFGYTGLLNFGQSAFLGVAAYGMAMMVATFGLPFWVGVAVGLAGAVVLALLLGIPTLRLRADYLAIVTIAAAEIVRLLFRSVSLSEWTGGSDGLQAFSDDFYAVNPYSSSLDIGTIISFDARELWVMTVGWVLVAISLLIVFLAMRSPWGRVIKAIREDEDAVRSLGKNVVSYKMQSLILGGVLGSLGGFIIALKNAAIQPDTYGTEFTFYMYTIVILGGAARVFGPVVGSMIFWFLLTFVNAVLPPAIAEGYIPSWLMTSTQAGAVGYILVGLGLILLLIFRPQGIFGDKKEVMLDGR
>NC_017093.1|WP_014441706.1|1714132_1716250_+|excinuclease-ABC-subunit-UvrB
MALDIPRLDGRFEVVSEFQPAGDQPAAINELERRVRRGDRNTVLLGATGTGKSATTAWLIERLQRPALVLAPNKTLCAQLAKEFRELLPNNAVEYFVSYYDYYQPEAYIAQTDTYIEKDSSVNEEVERLRHSATMSLLTRRDTIVVATVSAIYGLGTPQEYVERAVRVKVGGEIDRDKLLRRLVDIQYTRNDMAFQRGTFRVRGDTLEIIPAYEELAVRVELFGDEVEKLYYLHPLTGEVVREVDELIIFPASHYIAGPERMERAIRDIEAELADRLAEFERQGKLLEAQRLRMRTTYDIEMMRQVGFCNGIENYSMHMDGRSPGEPAYTLLDYFPDDFVTVIDESHVTIPQIGGMYEGDASRKRILIEHGFRLPSAADNRPLRFDEFLERVGQMVFLSATPGPWEMGQAQGEFVEQVIRPTGLVDPEVVVKPTKGQIDDLMHEIKLRTERDERVLVTTLTKKMAEDLTDYLLENGIRVRYLHSEVDTLRRVELLKELRKGDYDVLVGINLLREGLDLPEVSLVAILDADKEGFLRSGRSLIQTIGRAARNVSGEVHMYADKITPSMRDAIDETDRRRAKQIAHNEANGIKPQALRKKIHDILDDIYREAEDTDSAVAGPMVGGGGRQMSRGKAPVPETRSKARAGAGPAREGMARAELAQLIQDLSDQMLAAARELQFELAARIRDEVAELKKELRGMDMAGVK
>NC_017093.1|WP_041830611.1|1716637_1716967_-|antibiotic-biosynthesis-monooxygenase
MVLEVMLIDVLPGREDDFLNAYEAARPMFASVPGCRSVRVKQGMESAARFLLLVEWDSMEAQEQGFRRTERFAQWRALIAACIAQPPLSEFFGEVGVAGLSPTNNFFSH
>NC_017093.1|WP_014441708.1|1717604_1718600_+|TerC-family-protein
MNVPVWVWVATLVALVAVLAVDLLIIGRRPHEPSMKEAGTWVGFYVGLAVLFGIGVWATAGGQYAGEFYTGWLTEYSLSVDNLFVFVIIMARFAVPRHLQQKVLLIGIVLALLMRGAFIVAGAALIAQFSWVFYIFGAFLVYTAITLVKGGENDEEDFKENLLIRWAKRALPISSTFGDGRFSVVTETGKRLFTPMLIVTIAIGTTDLIFALDSIPAIFGITKEPYLVFTANVFALMGLRQLFFLLGGLLQRLVYLNIGLAVVLAFIGVKLFLEALHTNTLPFLNDGHGFHWAPEIPIWLSLLVILGTLGIATVASLIKSSRDRKRELINN
>NC_017093.1|WP_014441709.1|1718778_1720641_-|translational-GTPase-TypA
MQTRTDLRNVAIIAHVDHGKTTLVDAMLRQGSQSHARGEMADRVMDSMDLEREKGITILAKNTAISYQPAEGEPVIINIIDTPGHADFGGEVERGLTMVDGVALLVDASEGPLPQTRFVLRKALAAKLPIILIINKVDRPDARIKEVVDETYELFLDLDADEHQIEFPIVYACARDGIASLTQPKDGTVPEDSDNLDVLFSTILDTIPAPKYHEDAPLQAHVVNLDASPFLGRLALCRVHEGTIRKGQTVAWCKTDGTISNVRISELLITEGLERKPAESAGPGDIIAIAGISDIMIGETLADAENPVPLPLISVDEPAISMVLGTNTSPLVGKVKGAKVTARMVKDRLDKELIGNVSLRILNTERPDAWEVQGRGELALAILVEQMRREGYELTVGKPQVVTKVVDGKVHEPVERVTIDAPDEYMGAITQLLSTRKGRMEELINHGTGWLRMEWLVPARGLIGFRTEFLTETRGTGIMHHLYERHEPWFGELRTRQNGSLVADRAGAVTGFAMINLQERGQLFVEPGTEVYEGMIVGENSREDDMDVNITKEKKLTNMRAASADNTEKVIPPRKLSLEQSLEFCREDECVEVTPNAIRIRKVELDQNARGRAAARRKHQ
>NC_017093.1|WP_014441710.1|1720791_1721610_+|lytic-transglycosylase-domain-containing-protein
MNALLRTRLFAGLVVLVVAGGCGLAGASEEDKAVAPIAASSSAAEVTESPSPAPEPTEDLVVEESPSPSKKPASKKPKPSRTSATPTEDPNNFQPPDCAEFEGKEVSKAKAKAALNAAAAKTYWPTSAPKLKVPADLVRAVAWHESGWTSNIVNCDGGFGLMQVMPDTESFINQRFEQSYDSHAYRQNAVIGANYLAWLTKAFGDQYFKGNYSLSAAKCKSDSSLCLLNMVIAGYNMGRGSVDEGYANKELVNPEYVSVVRHLMRDCYCDKY
>NC_017093.1|WP_014441711.1|1721794_1722217_+|50S-ribosomal-protein-L11
MPPKKKTHEVTLALEAGNAAMVDLGKMLGPTGANMRAVKVEYDEATSKNRGEIIPVIVSVYEDRSHTLAYKTPPTSFLIKKSLGIPSGAANPLTTTVGTLSAAQVKEIAERKLPDLNANDLDAAIQIVKGTARSMGVKVA
>NC_017093.1|WP_014441712.1|1722273_1722903_-|ATP-dependent-Clp-protease-proteolytic-subunit
MYNRHDPNRWGFPPHPQPDWQPPHLPGSGPGLPGWLEERLFDQRIVMIRGQLTPDVATGTVAALLTLDSAGPDPIHLHMASSGGDLSAALSIIDVIDSLTAPVQALVTSEAGGAVLAVLAASDQRSAYRHARFKLAEPRAAGVTGTADEVAAAAGQHLRELEEVVVRLAEVTGQPRSRVEDDLSTGRTLSATEALEYGLITEVITPKPR
>NC_017093.1|WP_014441713.1|1723142_1723535_-|roadblock/LC7-domain-containing-protein
MTHPGDPYRPVYAELAGLRYQVPGVLACVVAGVDGLLILHDNTTGPEPHDVAALAAGAHGISRTTGAVLGQGGFADVTIHNQNGYLSVYAIGDLALLAVIGDGGLNIARLHLEARPVTARLAGLLQIRSV
>NC_017093.1|WP_041829618.1|1723531_1723873_-|hypothetical-protein
MGIEGAIGVALVDYTSGLTLGVLGGGQTMDMNIAAAGNTDVIRAKVRTLEMLGLQDGIEDILITLDTQYHLIRLLQNKRHGEAFFLYVSLDKSRANLGLARHQLRKIERELDV
>NC_017093.1|WP_014441715.1|1724253_1724763_+|SigE-family-RNA-polymerase-sigma-factor
MKIERDEQFHRFVVTRRAALVRTATLLTAGDAHLAEDLVQSTLTKLYVAWPAFQRADNPDGYVRRTLVNALTDERRRWWRRRERSMAELPDRPAAEIPGGDISDVLRAALKELPPRMRAALVFRYFYDLDVADTADALGCSEGTVKSQTARALDRLRAVLGQNPSLVLR

Crispr_ID: NC_017093_6

• CRISPR_ID: NC_017093_6
• CRISPR_location: 1745727-1745845
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_6

Consensus_repeat	Method
TCATGCTCGCCTCCACGCCCGGCCCTCGCGGGCCACCATCTCGTC	CRISPRCasFinder

spacers of NC_017093_6

>6.1|1745772|29|NC_017093|CRISPRCasFinder
CCTGTCGTCGAGGAGGTCCCCATTGGCGC

CRISPR arrays and Neighbor proteins around NC_017093_6

CRISPR arrays

The CRISPR arrays of NC_017093_6

>merge|NC_017093|6|1745727-1745845|CRISPRCasFinder
TCATGCTCGCCTCCACGCCCGGCCCTCGCGGGCCACCATCTCGTCCCTGTCGTCGAGGAGGTCCCCATTGGCGCTCATGCTCGCCTCCACGCCCGGCCCTCGCGGGCCAGCATCTCGTC

>NC_017093|6|6|1745727-1745845|CRISPRCasFinder
TCATGCTCGCCTCCACGCCCGGCCCTCGCGGGCCACCATCTCGTC	CCTGTCGTCGAGGAGGTCCCCATTGGCGC
TCATGCTCGCCTCCACGCCCGGCCCTCGCGGGCCAGCATCTCGTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_083888591.1|1753689_1754709_-|heme-A-synthase	unknown	unknown	gnl|CDD|224528
NC_017093.1|WP_051042417.1|1754818_1755511_+|ArsR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225222
NC_017093.1|WP_041829621.1|1741626_1742412_+|triose-phosphate-isomerase	unknown	unknown	gnl|CDD|234589
NC_017093.1|WP_014441739.1|1752070_1752364_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014441724.1|1736177_1737092_+|RNase-adapter-RapZ	unknown	unknown	gnl|CDD|235450
NC_017093.1|WP_014441728.1|1740430_1741627_+|phosphoglycerate-kinase	unknown	unknown	gnl|CDD|234613
NC_017093.1|WP_014441732.1|1743341_1743932_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|235142
NC_017093.1|WP_014441726.1|1738161_1739142_+|DNA-binding-protein-WhiA	unknown	unknown	gnl|CDD|273194
NC_017093.1|WP_014441738.1|1750909_1751854_+|protoheme-IX-farnesyltransferase	unknown	unknown	gnl|CDD|235293
NC_017093.1|WP_014441743.1|1755507_1756929_+|Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl|CDD|131035
NC_017093.1|WP_083888590.1|1748530_1750741_-|transketolase	unknown	unknown	gnl|CDD|223100
NC_017093.1|WP_014441740.1|1752363_1753263_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014441733.1|1743958_1744678_-|6-phosphogluconolactonase	unknown	unknown	gnl|CDD|376480
NC_017093.1|WP_014441744.1|1756969_1758097_+|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl|CDD|273908
NC_017093.1|WP_014441731.1|1742969_1743311_+|RNA-polymerase-binding-protein-RbpA	unknown	unknown	gnl|CDD|379162
NC_017093.1|WP_041829622.1|1742510_1742762_+|preprotein-translocase-subunit-SecG	unknown	unknown	gnl|CDD|235881
NC_017093.1|WP_014441727.1|1739422_1740424_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|223135
NC_017093.1|WP_014441736.1|1747393_1748506_-|transaldolase	unknown	unknown	gnl|CDD|235117
NC_017093.1|WP_014441745.1|1758093_1758426_+|non-heme-iron-oxygenase-ferredoxin-subunit	unknown	unknown	gnl|CDD|239604
NC_017093.1|WP_014441725.1|1737088_1738096_+|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	unknown	unknown	gnl|CDD|211689

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_083888591.1|1753689_1754709_-|heme-A-synthase	gnl|CDD|224528	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones].	2.31403e-35
NC_017093.1|WP_041829621.1|1741626_1742412_+|triose-phosphate-isomerase	gnl|CDD|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	3.61628e-145
NC_017093.1|WP_051042417.1|1754818_1755511_+|ArsR-family-transcriptional-regulator	gnl|CDD|225222	COG2345, COG2345, Predicted transcriptional regulator [Transcription].	4.62643e-48
NC_017093.1|WP_014441724.1|1736177_1737092_+|RNase-adapter-RapZ	gnl|CDD|235450	PRK05416, PRK05416, RNase adapter RapZ.	1.93963e-154
NC_017093.1|WP_014441728.1|1740430_1741627_+|phosphoglycerate-kinase	gnl|CDD|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NC_017093.1|WP_014441732.1|1743341_1743932_-|GNAT-family-N-acetyltransferase	gnl|CDD|235142	PRK03624, PRK03624, putative acetyltransferase; Provisional.	7.66066e-10
NC_017093.1|WP_014441726.1|1738161_1739142_+|DNA-binding-protein-WhiA	gnl|CDD|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	1.93699e-125
NC_017093.1|WP_014441738.1|1750909_1751854_+|protoheme-IX-farnesyltransferase	gnl|CDD|235293	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional.	1.76969e-130
NC_017093.1|WP_014441743.1|1755507_1756929_+|Fe-S-cluster-assembly-protein-SufB	gnl|CDD|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_017093.1|WP_083888590.1|1748530_1750741_-|transketolase	gnl|CDD|223100	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism].	0
NC_017093.1|WP_014441733.1|1743958_1744678_-|6-phosphogluconolactonase	gnl|CDD|376480	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase.	1.51639e-69
NC_017093.1|WP_014441744.1|1756969_1758097_+|Fe-S-cluster-assembly-protein-SufD	gnl|CDD|273908	TIGR01981, UPF0051_protein_Rv1462/MT1509, FeS assembly protein SufD. This protein, SufD, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. SufB and SufD are homologous. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	4.4708e-81
NC_017093.1|WP_014441731.1|1742969_1743311_+|RNA-polymerase-binding-protein-RbpA	gnl|CDD|379162	pfam13397, RbpA, RNA polymerase-binding protein. RbpA is a family bacterial RNA polymerase-binding proteins. RbpA acts as a transcription factor by binding to the sigma subunit of RNA polymerase.	4.82975e-54
NC_017093.1|WP_041829622.1|1742510_1742762_+|preprotein-translocase-subunit-SecG	gnl|CDD|235881	PRK06870, secG, preprotein translocase subunit SecG; Reviewed.	4.43526e-13
NC_017093.1|WP_014441727.1|1739422_1740424_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl|CDD|223135	COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism].	0
NC_017093.1|WP_014441736.1|1747393_1748506_-|transaldolase	gnl|CDD|235117	PRK03343, PRK03343, transaldolase; Validated.	0
NC_017093.1|WP_014441745.1|1758093_1758426_+|non-heme-iron-oxygenase-ferredoxin-subunit	gnl|CDD|239604	cd03528, Rieske_RO_ferredoxin, Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable microorganisms to tolerate and even exclusively utilize aromatic compounds for growth. ROs consist of two or three components: reductase, oxygenase, and ferredoxin (in some cases) components. The ferredoxin component contains either a plant-type or Rieske-type [2Fe-2S] cluster. The Rieske ferredoxin component in this family carries an electron from the RO reductase component to the terminal RO oxygenase component. BPDO degrades biphenyls and polychlorinated biphenyls. BPDO ferredoxin (BphF) has structural features consistent with a minimal and perhaps archetypical Rieske protein in that the insertions that give other Rieske proteins unique structural features are missing. CARDO catalyzes dihydroxylation at the C1 and C9a positions of carbazole. Rieske ferredoxins are found as subunits of membrane oxidase complexes, cis-dihydrodiol-forming aromatic dioxygenases, bacterial assimilatory nitrite reductases, and arsenite oxidase. Rieske ferredoxins are also found as soluble electron carriers in bacterial dioxygenase and monooxygenase complexes.	9.1289e-40
NC_017093.1|WP_014441725.1|1737088_1738096_+|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	gnl|CDD|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	3.45754e-81

Protein sequences

>NC_017093.1|WP_014441733.1|1743958_1744678_-|6-phosphogluconolactonase
MSETVVVVVPDADILASTVAARLAIKIIDAQAVHGTASVVLTGGRVAAKVLHAVRELPASAAIDWSRVDLWWGDERFLPSGDPDRNETQAREALLDKLPLDPSRVHAMPASDGPDGDDAIGAAARYIDELGSPLPRFDVLMLGVGEDGHVASLFPGHPGLQAEGSAAAVFDSPKPPPTRVTLTLSTIQSADEVWLIAAGPDKAKPIGAVHAGAHLPAASATGVRRTLWLLDRAAAAEIR
>NC_017093.1|WP_014441732.1|1743341_1743932_-|GNAT-family-N-acetyltransferase
MIRSYRASDLESIYDICVRTGAAGQDARGLYSSDRLLGDIWAVPYVVHEPQHAHVVDDGEGNVVGYVLGTADTPAFVEWYRTEWLPATADRMPAGDPRDEVMLGLHHDPERMLLPELAGYPAHLHIDLLPEAQGKGLGRGLMAAFLAGLRAAGVPRVHLGMAPENHGAYAFYQRLGFHDIPTQDTGALFLGRDTAM
>NC_017093.1|WP_014441731.1|1742969_1743311_+|RNA-polymerase-binding-protein-RbpA
MSSGSAIRGSRVGSSPMRPDERTEPAPRRQITYFCAAGHDSQIWFAAEAATPETWDCPRCGQPAGLDGANPPGRSRVEPYKSHLAYVKERRSEEDAQAILAEALAKLRQRRGE
>NC_017093.1|WP_041829622.1|1742510_1742762_+|preprotein-translocase-subunit-SecG
MPIAFAYTLIVLLIITSILLTLLILLHRGKGGGMSSMFGGGVTSSLAGSSVAEKNLDRYTVLVGIIWFACIVGLGFWLKLQLA
>NC_017093.1|WP_041829621.1|1741626_1742412_+|triose-phosphate-isomerase
MTTRKPIIAGNWKMNLNHFEAILLVRKLAEHLNAAQLDAVETVVLPPFTDLRSVQAAVEDDKLNIKFGAQDVSQHVSGAYTGEISGGMLAKLGCSYVVIGHSERREYHNETDELINAKIKAAFAAGLTPIFCVGEGLSVREESAHVGHCTAQVDAGLDGLKEDQIKQIVIAYEPVWAIGTGKTATPDDAQEVCGAIRARLAEKFGADVADAVRIQYGGSVKAGNIASIMAQPDVDGALVGGAALDAEGFASIVRFPEHVAR
>NC_017093.1|WP_014441728.1|1740430_1741627_+|phosphoglycerate-kinase
MKTLDDLLGEGVSGRRVLVRADLNVPFDKNNPGVISDDGRARAVLPTLIALRDAGARVIVMSHLGRPKGEPDPKFTLAPVATRLGELLGSPVAFAEDTVGASASAAAEALADGQVLLLENLRFNKGETSKDDAERGAFADELAKLADFYVDDAFGAVHRKHASVYDVAARLPHYAGGLVLTEVDVLKKVSESPEQPYVVVLGGSKVSDKLAVIQALLPKVDKLLVGGGMCFTFLKAQGYEVGKSLLEDEMVSVCADLLAQADGRIVLPVDVVAATEFSADATHDVVDASAIPADRLGLDIGPRSTALFADAIAGAKTVFWNGPMGVFELAPFAAGTRGVAEAITKIDGFSVVGGGDSAAAVRTLGLDESAFGHISTGGGASLEYLEGKTLPGVAALEK
>NC_017093.1|WP_014441727.1|1739422_1740424_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MTIRVGINGFGRIGRNFFRAVLASGADIEIVGVNDLTDNATLAHLLKYDSILGRLGHEVKASADEITVGGKSFKAFAERDPNNLPWGDLGADVVIESTGFFTDATKAKAHIDKGAKKVIISAPAKNEDITIVMGVNDNLYDGAKHTVISNASCTTNCLAPMAKVLNDTIGIEKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAVSLVLPELKGKLDGFALRVPIPTGSATDLTFTAARDTTVEEVNAAIKAAAEGPLKGILVYTEDDIVSADIVTDPASCIFDAGLTKVIGGNQVKVVGWYDNEWGYSNRLVDLVKLVGA
>NC_017093.1|WP_014441726.1|1738161_1739142_+|DNA-binding-protein-WhiA
MAMTAAVKDELSRVDVPKPCCRRAEMAALLRFAGGLHIVSGRVVVEAELDTGAVARRLRREIADVYGYPSEVHVLASGGLRKGSHYIVRIVKDGEVLARQTGLLDVRGRPVRGLPQHVVNGNVCCSVAAWRGAFMAHGSLTEPGRSSALEITCPGPEAALALRGAARRIGITAKEREVRGVDRVVIKDGDAIAALLTRIGAHSSVLAWEERRVRREVRATANRLANFDDANLRRSARAAVAAAARVTRALEILADDAPNHLTSAGRLRLEHRQASLEELGALADPPLTKDAIAGRIRRLLALADKRARDLGIPDTEAAVTPEMMAC
>NC_017093.1|WP_014441725.1|1737088_1738096_+|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK
MTGATPTRVVAFGGGHGLSASLRALRRCARDLELDITAIVTVGDDGGSSGRLRAERDALLPPGDLRQALAALADDHPTTRRTASLMQHRFAAMPAQRRTPDAERRADRSPDGLAGHAVGNLLLLGLIEMLGDPVLALDHAAQMVGARGRVLPMALHAVGIEADMVGPAGEAVTVRGQHAVAVADGRVTALRLHPANPPACPEALAAVREADWLIFGPGSWYTSVLPHLLVPDLAAAIVASPARRLVTLNLSADKETSGLSTADHLAALHWYLPELRVDAVLADAKWAGEPEPVRAAAQALGAELVLAPVAVADGSPRHDPESLGVALVPVLGSAR
>NC_017093.1|WP_014441724.1|1736177_1737092_+|RNase-adapter-RapZ
MQEPAREACVDEIVEPDEAGTDLVVVTGLSGGGRSTVARALENVGFYVVDNLPQALMLEMAELAFAAGGAARRTAMVLDVRSRAFSTDLAGAVRELKERGFSPRVVFVDADDEVLIRRFESVRRSHPLQGDGRLADGIAAERKLLEEARDQADVIIDTSHLNVNQLRRRVEELFSGDDSRRLRITVLSFGFKYGLPPDADYVLDARFLPNPFWVPELREHTGLEEGVSSYVLGQEGAGEFVGTYAGLIAATAPGFEREGKRYLTVAIGCTGGKHRSVAIAEELTARLNGMRLSAHTSHRDLGRE
>NC_017093.1|WP_014441736.1|1747393_1748506_-|transaldolase
MTDRLAELSAQGVAVWLDDLSRVRLTSGSLDKLRREQHVVGVTTNPSIFQKALSDADAYDSQVRDLAVQGVTVEEAIRLMTAKDVRWAADVFRPTYDASNGVDGRISIEVDPRKAHETESTVAEAKTLWWLVDRPNLYIKIPATLAGLPAITSVLAEGISVNVTLIFSVERYRAVMDAFLAGLEQAKANGHDLSKIGSVASFFVSRVDTEIDKRLDKIGSDSAKALKGKAAIANARLAYEAYTEVFGSDRWKALADAGAHPQRPLWASTGTKNPDFLDTIYVEELIAPGTVNTMPESVIFAFEDHGTTRGDTVSGNFADAHKVFDDLTAAGIDFADVFKVLEAEGVEKFEASWNELLEHVAKSLKVGTGA
>NC_017093.1|WP_083888590.1|1748530_1750741_-|transketolase
MCLGRSLRTCLARLDRVKPKRVPLFCPRSTTDVAATDPALNWSDLDRKAVDTTRVLAMDAVEKAGNGHPGTAMSLAPAAYLLFNRVMRHDPTDPEWAGRDRFVLSCGHSSLTLYVQLYLNGYSTSLDDLKSLRQWDSLTPGHPEYGHTPGVEITTGPLGQGVGNAVGMAMSARRERGLFDPDTAAGQSPFDHHVYALCSDGDIEEGVSHESSAIAAVQKLGNLTVIYDDNEISIEDDTRIAKSEDVGARYAAYGWHVQTVNWRGEDGYHEDVEALWNAIQTAKSVTDKPSFIVLKTIIGWPAPKKQNTGKIHGSALGADEIAATKEILGFANEPFAIDDEVVKHAQQVVERGKAARAEWQKAFDAWAAGNAEGKALFDRLATRTLPEGWHNALPEFPADEKGLATRAASGKVLEALAPVLPELWGGSADLAESNNTTMKGEPSFIPAEYATKEFPGHEYGRTLHFGIREHGMGSILNGIAVHGGTRPYGGTFLVFSDYMRGSVRLSALMKLPVVFVWTHDSIGLGEDGPTHQPIETLTALRAIVGLDVVRPADANETAYAWRGALEHTDRPTALALSRQNLPTIDRSKYASAEGTLKGGYILSEASTGEPKVILVASGSEVSIALTAQERLEAQGTPTRVVSMPCQEWFFQQDVAYQQQVLPRGVKARVSVEAGIRMSWDRILGDAGEAVSIEHYGASAPAKILFEQFGFTADNVVAKANASLARVGEITGHKTGN
>NC_017093.1|WP_014441738.1|1750909_1751854_+|protoheme-IX-farnesyltransferase
MITERPVRRRGPGGAKRAPGVENRRDRAAVLRGYLALTKPAIVELLLVTTVPTMMLAAGGWPNWVTFAVVLIGGALAGGAASALNCYIDRDIDQLMRRTKRRPLPAHEITPRAVLIFGLTLAVISVVLMAVFTNWLATALTAASIFYYDVIYTMWLKRRTPANTFWGGVCGAAPVIIGWAAVTGTISAMGWALFAVVFFWQMPHFYALAIKYKDDYARAGIPMLPVVRSMNRVNFEIVLYTVLTLAASFVAWPLGLGPIYGVTAIVMGLAFLAEAVRLAYVTRAGAPVNPMRLFHLSITYLTVVFMAVAVDGLI
>NC_017093.1|WP_014441739.1|1752070_1752364_+|hypothetical-protein
MAEGSVTTLTSEIKSFAAGHGGAKAVIEYVGKRGARIVLVGEDGEWSDQFAQDTGVAREACEHAGVAVENEWERELLEQMRPSNDLWRSMARRSMAR
>NC_017093.1|WP_014441740.1|1752363_1753263_+|hypothetical-protein
MSTPLADDGTVSQVALVTCATFPDLWDDDHPLRDALRERGVVVEAVRWDDESADWSRYDLTVIRSPWDYVARRDEFVAWAHRVPRLANPAGIVEWNTDKVYLRDLSEAGVPTIPTEFVAPGATWTPPSEGEWVVKPTISAGSQDTGRYALPAQLPLAEAHVRRLLDAGRTVMIQPYLTAVDTAGETAVLCTPDASGELTFSHAIRKGPMLTGPDDGSIQPGDEEISPRTPSAAELEVASKVLAAIPGGASSLLYARVDLIPGPDGTPTLIELELTEPSLFLRTSPAAAARLADAIVGRL
>NC_017093.1|WP_083888591.1|1753689_1754709_-|heme-A-synthase
MSGPARTIPRVKSSRSLLESASLSRPGQRLASALRPLALASLVANAGLIVTGAAVRLTGSGLGCPTWPKCTDDSYTTTAEMGVHGVIEFGNRLLTFVLVALAFATFFAALVSRPRRKSLIILSIAVALGVPGQGVVGGITVLTKLNPWVVGLHFILSIALIAGCYALWRRVDEGDGRPVPLVPTPIRHLAWITALVSFAVIAVGVVVTGSGPHAGDQGAKRNGLDPAAISQVHADLVFLLIGLSVALWFALRALNAPPATIRAAGVLIAVEFGQGIIGFVQYFTHLPVILVAAHMLGAAVTWTATLAVLWSLRTRPELPRPTDQPTPAVVQPAEPVPAS
>NC_017093.1|WP_051042417.1|1754818_1755511_+|ArsR-family-transcriptional-regulator
MSAVATATASDGRTRDRVAQLLLERGAATAAELGAELGLSPAAIRKHLDAMLAEQLVEVRVARLAGPRGRGRPAKRFVLTAAARESFPHHYDGIATAALRWIVEQHGPEALSAFASAQVQALEERLKAVILAAGTDPMARAEALAEALTAEGYAASATAIASGGQLCQHHCPVAHVAAEFPQLCDAETEVISRLIGTHVQRLATIAHGDGVCTTHIPATQTTAITVRTDK
>NC_017093.1|WP_014441743.1|1755507_1756929_+|Fe-S-cluster-assembly-protein-SufB
MTDQIVTQEEHLAALGRYEYGWADTDTAGATAQRGLSEAVVRNISGLKNEPQWMLDLRLKGLRLFDRKPMPNWGADLTGIDFQNIKYFVRSTEKQAATWDDLPEDIKATYDKLGIPEAEKQRLVAGVAAQYESEVVYHAIREDLEAQGVLFLDTDTALREHEDIFKEYFGTVIPVGDNKFAALNTSVWSGGSFIYVPKGVHVDIPLQAYFRINTENMGQFERTLIIADEGSYVHYVEGCTAPIYSSDSLHSAVVEIVVKKNARVRYTTIQNWSNNVYNLVTKRATCEEGATMEWVDGNIGSKVTMKYPAVYMTGAHAKGEVLSIAMAGEGQHQDSGAKMVHAAPHTSSTIISKSIARGGGRTSYRGLVQVLEGSSSSKSTVKCDALLVDTISRSDTYPYVDIREDDVNMGHEATVSKVSEDQLFYLMSRGLTEDEAMAMIVRGFIEPIAKELPMEYALELNRLIELQMEGAVG
>NC_017093.1|WP_014441744.1|1756969_1758097_+|Fe-S-cluster-assembly-protein-SufD
MTTEAIAPPSTKSQVLRSFDVADFPALNGLEEEWRFTPLKRLRDLAKATSLTGVAPSVEFSGLPAGVTVSAVDTVDAVLTPFDRISALAYGSAAGVTLIEVAAEAEPAEAAVIRLVGKGGDAAAARTFVKVGAFAKATIVLEQTGSVTLADNIEVVIGDGAQLTFVTLAEWDADAVQAQHVKFRVGKDARVQHLQVTLGGDLVRQFTSVEYAGRGGEAELFGLYFADAGQHQEHRQLVDHSVPDCRSYVGYRGALQGASAHTVWVGDVLIRAAATGTDTYEINRNLVLTDGARADSVPNLEIETGEVAGAGHASATGRFDDEQLFYLMARGIPEDEARKLVVRGFFAELINKIPVEELRERLGDAIEARLAEAGQ
>NC_017093.1|WP_014441745.1|1758093_1758426_+|non-heme-iron-oxygenase-ferredoxin-subunit
MTFENVGPASDVAKGTALQVEVDGVEVAIVHADDDNFYAVRDECSHASVALSEGEVDGCTLECWLHGSRFDLRTGEPSGPPAIDPVAVYPVEIRDGDIYVSTTPSNGVEP

Crispr_ID: NC_017093_7

• CRISPR_ID: NC_017093_7
• CRISPR_location: 2021893-2022107
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_017093_7

Consensus_repeat	Method
GCCGTAGCTCAGGCATGTGATCAAG	CRISPRCasFinder

spacers of NC_017093_7

>7.1|2021918|39|NC_017093|CRISPRCasFinder
GCGCCGAGCCGTAGCCCAAGCAGGTTCCCGGGGCGCCGA
>7.2|2021982|38|NC_017093|CRISPRCasFinder
CCACGGGGCCGTAGTTGAGGCAGGTTTGGAGCCCGCGA
>7.3|2022045|38|NC_017093|CRISPRCasFinder
GGGTGACTGCCGGTCTGGACTACGGCTCGTCGGTCTCG

CRISPR arrays and Neighbor proteins around NC_017093_7

CRISPR arrays

The CRISPR arrays of NC_017093_7

>merge|NC_017093|7|2021893-2022107|CRISPRCasFinder
GCCGTAGCCCAAGCAGGTTCCCGGGGCGCCGAGCCGTAGCCCAAGCAGGTTCCCGGGGCGCCGAGCCGTAGCTCACGCAGGTTCCCGGGCCACGGGGCCGTAGTTGAGGCAGGTTTGGAGCCCGCGAGCCGTAGCTCAGGCATGTGATCAAGGGGTGACTGCCGGTCTGGACTACGGCTCGTCGGTCTCGGCCGTAGCTCAGACATGTGATCAAG

>NC_017093|7|7|2021893-2022107|CRISPRCasFinder
GCCGTAGCCCAAGCAGGTTCCCGGG	GCGCCGAGCCGTAGCCCAAGCAGGTTCCCGGGGCGCCGA
GCCGTAGCTCACGCAGGTTCCCGGG	CCACGGGGCCGTAGTTGAGGCAGGTTTGGAGCCCGCGA
GCCGTAGCTCAGGCATGTGATCAAG	GGGTGACTGCCGGTCTGGACTACGGCTCGTCGGTCTCG
GCCGTAGCTCAGACATGTGATCAAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_083888780.1|2015804_2016932_+|IS701-family-transposase	unknown	unknown	gnl|CDD|379252
NC_017093.1|WP_014441969.1|2014732_2015674_+|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl|CDD|376667
NC_017093.1|WP_014441972.1|2020907_2021831_-|YegS/Rv2252/BmrU-family-lipid-kinase	unknown	unknown	gnl|CDD|183857
NC_017093.1|WP_014441974.1|2025296_2026382_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|316372
NC_017093.1|WP_014441981.1|2036436_2037585_+|glycosyltransferase-family-1-protein	unknown	unknown	gnl|CDD|340842
NC_017093.1|WP_157434783.1|2038045_2038306_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_051042428.1|2012206_2012770_+|copper-resistance-protein-CopC	unknown	unknown	gnl|CDD|377255
NC_017093.1|WP_157434782.1|2028309_2030331_-|response-regulator	unknown	unknown	gnl|CDD|237425
NC_017093.1|WP_014441975.1|2026414_2028223_-|VanW-family-protein	unknown	unknown	gnl|CDD|225341
NC_017093.1|WP_041830651.1|2012808_2013519_+|YcnI-family-protein	unknown	unknown	gnl|CDD|377951
NC_017093.1|WP_014441970.1|2017108_2018104_-|ribonucleotide-diphosphate-reductase-subunit-beta	unknown	unknown	gnl|CDD|153108
NC_017093.1|WP_014441979.1|2034875_2035031_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014441971.1|2018184_2020545_-|ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl|CDD|235966
NC_017093.1|WP_157434781.1|2022426_2025300_+|hypothetical-protein	unknown	unknown	gnl|CDD|226418
NC_017093.1|WP_014441967.1|2013575_2014136_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_017093.1|WP_014441980.1|2035065_2036205_+|MFS-transporter	unknown	unknown	gnl|CDD|340928
NC_017093.1|WP_014441977.1|2030425_2033644_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|236848
NC_017093.1|WP_014441964.1|2010471_2011911_-|PepSY-domain-containing-protein	unknown	unknown	gnl|CDD|225723
NC_017093.1|WP_014441978.1|2033612_2034623_-|TerC/Alx-family-metal-homeostasis-membrane-protein	unknown	unknown	gnl|CDD|274743
NC_017093.1|WP_014441968.1|2014205_2014568_-|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl|CDD|226323

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_083888780.1|2015804_2016932_+|IS701-family-transposase	gnl|CDD|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.68805e-51
NC_017093.1|WP_014441969.1|2014732_2015674_+|sulfite-exporter-TauE/SafE-family-protein	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	8.44101e-35
NC_017093.1|WP_014441972.1|2020907_2021831_-|YegS/Rv2252/BmrU-family-lipid-kinase	gnl|CDD|183857	PRK13057, PRK13057, lipid kinase.	6.84769e-55
NC_017093.1|WP_014441974.1|2025296_2026382_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|316372	pfam13847, Methyltransf_31, Methyltransferase domain. This family appears to have methyltransferase activity.	3.49134e-21
NC_017093.1|WP_014441981.1|2036436_2037585_+|glycosyltransferase-family-1-protein	gnl|CDD|340842	cd03814, GT4-like, glycosyltransferase family 4 proteins. This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.	5.24708e-118
NC_017093.1|WP_051042428.1|2012206_2012770_+|copper-resistance-protein-CopC	gnl|CDD|377255	pfam04234, CopC, CopC domain. CopC is a bacterial blue copper protein that binds 1 atom of copper per protein molecule. Along with CopA, CopC mediates copper resistance by sequestration of copper in the periplasm.	3.43513e-22
NC_017093.1|WP_157434782.1|2028309_2030331_-|response-regulator	gnl|CDD|237425	PRK13557, PRK13557, histidine kinase; Provisional.	3.04901e-81
NC_017093.1|WP_014441975.1|2026414_2028223_-|VanW-family-protein	gnl|CDD|225341	COG2720, COG2720, Uncharacterized vancomycin resistance protein [Defense mechanisms].	3.97577e-57
NC_017093.1|WP_041830651.1|2012808_2013519_+|YcnI-family-protein	gnl|CDD|377951	pfam07987, DUF1775, Domain of unkown function (DUF1775). Domain found in bacteria with undetermined function. Its structure has been determined and is an immunoglobulin-like fold.	2.22455e-61
NC_017093.1|WP_014441970.1|2017108_2018104_-|ribonucleotide-diphosphate-reductase-subunit-beta	gnl|CDD|153108	cd01049, RNRR2, Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain. Ribonucleotide Reductase, R2/beta subunit (RNRR2) is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The RNR protein catalyzes the conversion of ribonucleotides to deoxyribonucleotides and is found in all eukaryotes, many prokaryotes, several viruses, and few archaea. The catalytically active form of RNR is a proposed alpha2-beta2 tetramer. The homodimeric alpha subunit (R1) contains the active site and redox active cysteines as well as the allosteric binding sites. The beta subunit (R2) contains a diiron cluster that, in its reduced state, reacts with dioxygen to form a stable tyrosyl radical and a diiron(III) cluster. This essential tyrosyl radical is proposed to generate a thiyl radical, located on a cysteine residue in the R1 active site that initiates ribonucleotide reduction. The beta subunit is composed of 10-13 helices, the 8 longest helices form an alpha-helical bundle; some have 2 addition beta strands. Yeast is unique in that it assembles both homodimers and heterodimers of RNRR2. The yeast heterodimer, Y2Y4, contains R2 (Y2) and a R2 homolog (Y4) that lacks the diiron center and is proposed to only assist in cofactor assembly, and perhaps stabilize R1 (Y1) in its active conformation.	1.34961e-103
NC_017093.1|WP_014441971.1|2018184_2020545_-|ribonucleoside-diphosphate-reductase-subunit-alpha	gnl|CDD|235966	PRK07207, PRK07207, ribonucleoside-diphosphate reductase subunit alpha.	0
NC_017093.1|WP_157434781.1|2022426_2025300_+|hypothetical-protein	gnl|CDD|226418	COG3903, COG3903, Predicted ATPase [General function prediction only].	6.67262e-29
NC_017093.1|WP_014441967.1|2013575_2014136_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	0.00119074
NC_017093.1|WP_014441980.1|2035065_2036205_+|MFS-transporter	gnl|CDD|340928	cd17370, MFS_MJ1317_like, MJ1317 and similar transporters of the Major Facilitator Superfamily. This family is composed of Methanocaldococcus jannaschii MFS-type transporter MJ1317, Mycobacterium bovis protein Mb2288, and similar proteins. They are uncharacterized transporters belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.63536e-83
NC_017093.1|WP_014441977.1|2030425_2033644_+|PAS-domain-S-box-protein	gnl|CDD|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	4.61064e-119
NC_017093.1|WP_014441964.1|2010471_2011911_-|PepSY-domain-containing-protein	gnl|CDD|225723	COG3182, PiuB, Uncharacterized iron-regulated membrane protein [Function unknown].	7.89812e-65
NC_017093.1|WP_014441978.1|2033612_2034623_-|TerC/Alx-family-metal-homeostasis-membrane-protein	gnl|CDD|274743	TIGR03718, R_switched_Alx, integral membrane protein, TerC family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family often are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains TerC itself from Alcaligenes sp. plasmid IncHI2 pMER610 and from Proteus mirabilis. It also contains the alkaline-inducible E. coli protein Alx, which unlike the two TerC examples is preceded by a yybP-ykoY leader.	1.54297e-119
NC_017093.1|WP_014441968.1|2014205_2014568_-|MmcQ/YjbR-family-DNA-binding-protein	gnl|CDD|226323	COG3801, COG3801, Uncharacterized protein conserved in bacteria [Function unknown].	4.79602e-15

Protein sequences

>NC_017093.1|WP_014441972.1|2020907_2021831_-|YegS/Rv2252/BmrU-family-lipid-kinase
MRTKQQLTDDIRSERRAALVVNARSRRGRQFYDDAHARLQAAGFKLLGSYGVEGDLERSLQRAIDLGPDLLVAGGGDGTISTAGRMLAHRDMALGLLPLGTTNNFARTIGIPPDLDTAITTMTDGLVIDVDLGIAGDMPFTNHVGVGLSAEVMINAPSRLKRAIGRFAYPITALGLLRRHRPLRATVHAEGREIVFTTHQVYVANGGFHAGRPITADAHADDRLLVAYPVGGATRRELLRETARNALTGHRRTLHERPFLAVGELWLETDRPAAVEVDGEPCGRTPLRIALDANALRIMAPPGTEDH
>NC_017093.1|WP_014441971.1|2018184_2020545_-|ribonucleoside-diphosphate-reductase-subunit-alpha
MQTEQKLHTEQRRHTMQVRKRNGETEPVDVNKIVTAVERWVADLDEVDPLRVATKTISGLYDGATTAELDKLSIQTAAELIGEEPQYSRLAARLLAAFVEQEVREEGVAGFSESIRLGHQQGLISDETAAFVAEHATVLDQAIDDANNLRFEYFGLRTVADRYLLRHPTKRTVIETPQHWLLRVACGLSETPGEAIGFYRLMSSLAYLPSSPTLFNSGTRHTQMSSCFLVDSPKDELDSIYERYHQVAKLSKFSGGIGISWSRVRGRGALIRGTNGKSNGIVPFLKTLDAGVAAVNQGGRRKGAACVYLEPWHPDIEEFLELRDNTGEESRRTHNLNLANWIPDEFMRRVEADEDWSLIDPSDAPMLPDLFGDEFTEAYRAAEKNAVKTIKARDLYGRMMRTLAQTGNGWMTFKDPSNRLSNQTGAPGNVIHLSNLCTEILEVNNDAETAVCNLGSVNLGAHVTADGVDWEKLRETVRTAVVFLDRVIDINYYPAQQAAASNPRWRPVGLGLMGLQDAFFTLRLPFDSAEARELSTRVQEEIFLTALESSAALAERFGPHPAYPETRAAKGDLHPYLWGAEPSQNARWAAVKERIAAHGLRNSLLVAIAPTATIASIAGCYECIEPQVSNLFKRETMSGEFLQINTYLVRELKSRNLWTAGIREAIKRAEGSVQGIAELPADVRELFRTAWELPQRALIDLAAARAPYIDQSQSLNLFMAAPTIGKVSSMYLYAWKAGLKTSYYLRSRPATRIQQATVSVAPSVIPALTPAEVCSLENPESCEACQ
>NC_017093.1|WP_014441970.1|2017108_2018104_-|ribonucleotide-diphosphate-reductase-subunit-beta
MLLDPGMDLTLRPMKYPHFFDRFKDAIKNTWTVEEVDLHSDLADLAKLTPAEQHLVSRLVAFFATGDTIVANNLVLNLYQHVNSPEGRLYLSRQLFEEAVHVQFYLNLLDTYVPDPDERAAAFAAVDNIPSIARKAEFCFKWIDSVFELRELRTKADRRAFLLNVICFAACIEGLFFYGAFAYVYFLRSRGLLQGLASGTNWVFRDESMHMAFAFDVVDQVRAEEPDLFDAEMEQQVRDMLAEAVECEVQFAADLLEQGVSGMSLGDMREYLQHVADRRLAALGIAPIYGSTNPFAFMELQDVQELSNFFERRVSAYQVGVTGSVSFDDDF
>NC_017093.1|WP_083888780.1|2015804_2016932_+|IS701-family-transposase
MEFDQWSSELDRLHARFADRFTRAEPRRRARQYLSGLVAGLDRKNGWTLAEQAGDLSPDGMQRLLRWADWDIDAVRDEVRDYVIEHLGDPNGVLIIDDTGFLKKGVKSAGVARQYSGTAGRIENCQVGVFLAYRSTRGHALIDRQLYLPAAWTDDRDRCRAAGIPDEVGFATKIEMARQMLQRAFTAGVAAAWVTMDEAYGQSKALRVWLEEHDQPHVVATRCNDDVVTTSMGRARVDELIASLPGRAWSRISAGPGAHGPREYWWARIPIRICWRPGRGHWLLARRSMNTGELAYYVCYGPRKTRLMDLARIAGTRWAVEECFQQAKGQAGLDEYQVRDWRAWYAHITLSMAAYAWLVVARTQTAQQQTAPVTT
>NC_017093.1|WP_014441969.1|2014732_2015674_+|sulfite-exporter-TauE/SafE-family-protein
MQKLLLLALVGLGAQLVDGSLGMAYGVTSTTLLLAIGTNPAAASATVHLAEIGTTLVSGFSHWKFGNVDWKVVLKIGVPGAVGAFAGATFLSNLSTETAAPLMAIILLALGLYVFLRFTFQGLPQGHLGKPLRKRFLGPLGLVAGFVDATGGGGWGPVGTPAILASGRLEPRKTIGSIDTSEFLIAIAASLGFIWGLGDENIDYGWVAALLIGGVIAAPIAAWLVRHIPPRVLGAAVGGLIILTNTRSLLRSDWIDASDPVRYTFYAVIYLAWAAALVYSINQYRSHKAEDERIIAEAEAAAETPDEKASTPA
>NC_017093.1|WP_014441968.1|2014205_2014568_-|MmcQ/YjbR-family-DNA-binding-protein
MADADDVRRLALALPGVVEIDSDGFDFRVGNRGFVWSYPERMPGKPRRIRTDVAVLYVGDEAEKQALLLGEPALFFTTPGYDGLPLVMLRLPEVSADRLDELITDAWRMRAPEDLAADET
>NC_017093.1|WP_014441967.1|2013575_2014136_-|GNAT-family-N-acetyltransferase
MSLEVDGVKSAVEITDRVDLEALADVYRRVHAADLHLVDHSDPSLEDRLRWTAEAPGFEAAVGYVDGEIVGTVMGCPLPAETLWWRDLTDAQDPELAVEWEGRTFAVCEAFVLPEFRKHRLGVRMMNDLLEKRSEERVCLAVTETNTRVWHALQRLRFQHVGDLVPFPGWRSHRMLVRALPLSASR
>NC_017093.1|WP_041830651.1|2012808_2013519_+|YcnI-family-protein
MMNLRRTAAVSAVAAAFVLAVASPAAAHVTVNPSTATQGGYTKVSFRVPNESDTASTTKLEVSLPTDAPVGSVSLKPVPGWTATTEKSKLATPVEVHGAPLTEAVSKITWTAAKGSEIKPGTFQEFDVSLGPLPKTDQMVFKALQTYSDGNIVRWIDEPTTDGTEPESPAPVLKLTAAGAEATGTAPSAVAVAPVAAESDDSDSGSGTAWGIAGLVAGLAGLVLGLLAYRKAATKP
>NC_017093.1|WP_051042428.1|2012206_2012770_+|copper-resistance-protein-CopC
MALAAMLAVLLPGAPAWAHNALTDANPAKNATLASAPESVKLKFLQKLNPEYTVITVTDAEKRKVATSEPKIDGATGTVTFDEGLGNGVYTVAYQVVSTDGHTVKGSYKFTVDDPNVIEQTVEPSATPQSDAYSSQLTINGTPTQLPADAAPASDSGGSSTLAWVAGVLILIFAGLAGFVVIRRRKA
>NC_017093.1|WP_014441964.1|2010471_2011911_-|PepSY-domain-containing-protein
MAVSPPPQLELADPPAARPARRASGFGALLLRLHFYTGILIAPFLVVVAVTGLLYTVTPQLDQMLYGDKLTVTAGNATVPLADQIATARAAHPAGTLTAIQPGSGSDSTRVVFSLPDLEEKQHTVYVDPHTGTALGQLTTWYGSTPVTTWLDDLHRNLHLGDLGRHYSELAASWLWVLALGGLILWWRRRRSLRGVLTPDMAAKKGVRRTRGWHAATGVWISVGLLVLSATGLTWSRYAGGNFTTALDSLDAHAPTLDVAAAPALDVAAAPALGGAAAPAASGGHHGGSAAVALADPAQADTVVRVARDNGLTGTVELTVPETATAPWTVAGIDNVWPVGLDRIAVDPASATVVARSDFADWPVLAQLSKLGVQAHMGVLFGVVNQVLLAALAVGLLCVILWGYRMWWQRRPTRADRRRAMAGAPPARGGWLGLPAWAIVVGVPVVFAVGWAMPLLGVTLVAFLLVDAVVGGVRDSRTS
>NC_017093.1|WP_157434781.1|2022426_2025300_+|hypothetical-protein
MGIRVGVLGPVELTRDGVPVPLTGVPQRVLLARLALAGGRPVSVAELIDALWEGAPPDNAVGNLHSYVSRLRRHTGGDVIRRDPGGYRLALESDDHATGARRDDAGRVGDHATGERPGDAGRGGGGLDVDVVEGLVGVARRQPADLAAATLARALDVWRGEPLADIADRLAFAPDVARLTEWRRHLREECLDRRIDAGQAAEALPEIEALALAEPLRERPHLLLMRALHATGRAAEALTVLRAYRERLSEDHGLDPSPAMIDMQRRILEEDPERPRRTRSANRFFGRTAELAAIRAALGTDRVITLVGPGGVGKTRLMTEALSGEELVVELAERSVPADVAAAVAGALGMRSAPRGGVTALAERLGASPSVLVLDNCEHLLDAVRVLVSELIARCPEVRVLATSRQRLDVAGERVVRIGPLPASDRVALFCDRAALLRADFRDDSRTRELAAQICELVDGLPLAVELAARREAVFGLAHLRDRLGAGLNVLDPARGGDRATGVSATVEWSYRLLDPAAQRLLDHLAVCRGGFGLDALPYFQEDAEPLLAELVDASLVTCDLSGEQPRYRLLETVRHVGIGHLGPDGERQARAAHARWMSDLARELVRRGRDRDPWTTPTLRREVANLQEALQWMGGHDEEAGARMAALLAVINSDAPDPGLTEQLAGWRPDRVETESDVLRGLAAGNAEWLRGNLAEADRLLTAVLDRMPGDHPLRWGALVVRISNAMFAGRAADVRADAERMATDPGAPRWARATGICCAALMDVYGGDPDTGLAWLDRYAEHLNTDGLDGFVPFTRGELIAARDPAGALAWYDLSIAANDRVNQVYGGNVARVARAAVLIRLGRHDEAVTACRETIVAVRNANMTAQVWTMARLVAELLAALGDPEAAAALVAAADADPFAPAVMGPDRERLARLRGPAPVTIHDPVRFCLQRLATGAGMGSARHQQAPPRIVRS
>NC_017093.1|WP_014441974.1|2025296_2026382_+|class-I-SAM-dependent-methyltransferase
MTTDTQQTPTVDEARVEAFAGQLITDFAGAATTAMTVLGDRLGLYRALTGAGPVTAAELAQRTGLHPRLVTEWLRQQAVSGYLTVDGDTYELPFEHALALSVVDSPAYLVAAGEIIAGYFQSLENLEQAFRGTGGLSGDEVPGCTYHGIERYFRTAYVNQLAQAWFPAVPGLVAKLEAGARIADVGCGHGFASLLIGRTWPASTVAGFDLHEPSVATARARAIEAGSPPNVSFHVADSAALDGHGRFDVVVFFDALHDMGDPVAALRAAHAALNPGGIVVAVEPWSADDWTSTIGMPITRIGYASSTALCTPTSLGQPGAYGLGTLGGPSPRLDLLAAAGFADPIVAADTGFNLVVSATKI
>NC_017093.1|WP_014441975.1|2026414_2028223_-|VanW-family-protein
MSTAGEPRPAVDDALTVRLPAQPTGSHDVLDSSDPAPPPAPGTRRTGRRALITGAAVLVLAAGAGTAVTWAYRGEVPLGVTVLGAELGGLSRTEAAAELRTHLAADARLSQPVTVRVEDRQASVKPADVGLVVDVDATVAAAAQGSPSPFGERAVPPVVAVDPDLLDAALRTSLGTIGEPMTKPAVVFDGVKPRAVHPEAGRGLDPARTAATIRDSWPASRAVTVPLVEVHPVTTAAEVDQLVTDLAEPAVSGPLTITADSGTVTVPPSAIAKSLVLTSDKTGRIEPRVDAKKLRAAVKKPLAKVEKKAKDARFSLKGGKPSIVGGADGTAVDLAAMAPEILTALRSTTERTIAATVTRAEPELTAAELGELGVKEKVSTFTTKFTGGLSSPRSQNIVQAAKQVEGTLVLPGETFSLNKHTGERGYQQGYQDAPVILGGKLTPGVGGGVSQFTTTLFNATYYAGLKDVEHKPHSYYFDRYPAVIESTIFYPDLDFKFKNDSPYGVLLDTAWTRNSITVSVWSTKVWDKVSTEWSRRRNITSPRTITLPAGPSCIATGGLPGFTQDAYRLFERDGKVVKREKFTWKYDAEPNYICGGADDSAG
>NC_017093.1|WP_157434782.1|2028309_2030331_-|response-regulator
MATVMVVDDVAANRDIVRMLLGYRGHDVIEARDGADALRLAHVHHPDVVVSDVLMPGIDGLELVHRLRSDPDRLAAQAPVIFYTANYLEPETRPIAEACGVSQVVLRSQDPHTLLEAIDTALAQGPVLIDVPPAADEEFAQAHLHAVNAKLIEKVRALHDTERRFEAMAVASPVGICILDTHGTADYINERFTEIMQMPQESLLGQGWLDCLDDSAQDAALSLLHGAGETAELRFDHRISWPDGTTRRLRLHLRQIHDDDDGRLAGGVLMVDDVTDLVSAEERLREEIMRRQEDSRHRDAERLDSLRRMAGGTAHDFNNILGAILGYTNLAIETINDGLEDGTVPAETAESLLGDLQHVVKGGERAKGLTQQLLAFGRREIIQPAPINLNALLRDDTPSLRETAGDAELILDLDPALPDVKADPAQISQALRSLVRNSAEAMPSGGTVTVTTSAQDDMVTVSLTDTGAGMPQHVLDRAFEPFFSTKPAGSTAGLGLSTAHGIISQAGGQLTLRSQEGRGTTATFTLPALITETPAPPPSPTGTDETGGETLLLVDDEAAVLQVSARILSSAGYDVLTANDAGEALRILEQHPGHVSALVTDVVMPGMNGRQLAKVAAMRQPSLSIVFVSGFAESLIDENGNNLEPGSTILAKPFDREALVSTVRGALNATAHR
>NC_017093.1|WP_014441977.1|2030425_2033644_+|PAS-domain-S-box-protein
MRKAAWVRYGLIAGGLAGAGVTIGGELLRRAGRRLDQYFYLAAILEQTATPAFVKTVNGRYRLVSGAYERLHQVPAGVAAGRYDHEVHPPEKLTEYRRRDRMVLAADGPLAFEDEVVDFERVRRYVTTLYALRDRRNRPYAIFGVSTEVSEQNRATRQAASERRLQSEINARLAAIVEASQDAIVSKALDGTIRTWNPGAERLYGYTAEEMVGNDVTRLLPPDRQHEERELLARVFAGEALSRFETRRQRKDGSIIEVSLSMAPMRDTDDSVIGVSTVAHDITARVRAEQRLRLEREQLETIMGAASDPFFTMDDDGLISEWNRQAEHVFGWGRDAIIGRNVTDTVLPVRYRPALRRLLDGQWDWLLDRPTEMAATHRDGHEIPVELTMWRIGHDGGVHFHGFVRDITARRQTEQALAEARDQAIETARLKSQFLASMSHEIRTPMNGVIGLTGLLLGSDLDEKQRRYAEGISAAGTTLLAVINDVLDFSKLEAGKVLLEEANFQIGRLIDDVVSLVAPPGTRDAVTVGGVCDPRLPETVCGDPTKLRQVLLNLAGNAVKFTTEGRVTVTAALDEGQSTGPDAVPIRFEVRDTGIGIDGERQEELFEAFTQADAGTTRRFGGTGLGLAISRDLVELMGGSIGVESEPGHGSMFWFTVTLRTARDDLDLTERHSLDGLRVLIVDRDEQDRNVLTDQLTGWSMRAGTASDVPGAQTALREAAAAGRPIDLVIVDIGTAEADGLDLAGFAIAPPGCPPPKMILLADEAHHLPGEPDPESFSAAFAKPLRQSQLYDALVGVLTGDTGEPAAGAAGETPTGRGHLLLVEDNDINRTVALGVLANLGYSADVAVNGLEAVALATRREYRAIFMDCLMPEMDGYAATAEIRRREPEGRHVPIIALTASALAEDRARCLAAGMDAHIAKPLVPGDVARVLDRWTSRLPAQDVGTVIDEIDKRLDQLRGPDPVATATALDGLLGALAGKIPEHLDRIAHALAFDDAAQLRSEAHQLKGIMANLGVGAATLACGRLEDDARAGDLDAAVASFAHARPQVATVGRAVERIRRRFSEETAAPVS
>NC_017093.1|WP_014441978.1|2033612_2034623_-|TerC/Alx-family-metal-homeostasis-membrane-protein
MSEEALLSSLSTIASPQLWAITIVVLLALLAADFAITHRPHDVAMREAVGWSLFYLALPGAFGVLLWQVYGRKPAVEFYTGWVVEKSLSVDNLFVFMLLLAAFAVPAQLAQRVLLYGIVGALVLRAIFIAAGAAVLQTGTWAFLLFGAALLLTAAKVMRDAVRDEEYHVDIDSMRSVRLLRRMMPVTRDYHGGRLTVRLDGRRTLTPLALVVVAVFVTDLVFAVDSVPAVYGVTEDPYLVFATNAFALLGLRALYFVLRNALGKLRHLDYGLAVILAFIGVKLVLHWAHKVWPQVPDIPTELSLVVIALALTTVTVTSLVANRREAVRTPAPPSPR
>NC_017093.1|WP_014441979.1|2034875_2035031_+|hypothetical-protein
MLLDILVGTVVMVCLLVSSIALLPPPARHGRGHGHHRAAFHFHWPHFRRHS
>NC_017093.1|WP_014441980.1|2035065_2036205_+|MFS-transporter
MSPWRAITAFGLVSLAADMVYEGARSITGPLLGTLGASALVVGLITGAGEAAALLLRLVSGPLADRTARYWTLTIAGYGLTALCVPLLAVAPALGGAGLAVAGLLIVAERVGKAIRSPAKSALLAEAAGQVGRGRGFAVHKALDQIGAFAGPLLVAALVAAFTLPAALAALAIPGALAMALLFWLRPRFPAPDGRDTAIVSGRLPRRFYLFALAMAASTAGLVTFGLISYHASESGGLPLATVPLLYAAAMAAGAVAALLSGHLYDRWGPRVLYALPALAAAMPALAFAGSMPAIVAGTLLWGAAVGVQDSTVKALVADLVAAPRRATAYGVFAAIQGAAALGGGVLAGALYGYSITLLAVVLAVLQGVAAVLLAVTRA
>NC_017093.1|WP_014441981.1|2036436_2037585_+|glycosyltransferase-family-1-protein
MRVVLATESFLPDVNGVANSVARMAEHLVRSGHEPMVVAPSPPAGSRAVGDLPYPVVRVRSLPMPGYPQLRLGLPAPALHAAIRAHDPDVVHLASPFVLGAWAQASAKTLGLPSVAVYQTDVAAYARAYRVRLTERMAWRWIRTVHNAATRTLAPSTESVTALQAHGVRRLHLWRRGVDDVRFHPSRRSAAIRRALAPGGEVLVGFVGRLAAEKEVELLAGASRLPGVRVIVVGDGPAAASLRRALPGALFLGARHGSQLARIYASLDVFAHTGPYETFGQAVQEAMASGLPVVAPAAGGPLDLVTHGRTGYLVPPHETAGFTGAIASLAGDPSLRRAMGEAGRESVRGRSWSAIGDELLAHYRAVTTVPVAIPLPPLPSRA
>NC_017093.1|WP_157434783.1|2038045_2038306_-|hypothetical-protein
MDGPAAPTCAGVILGLTWSTLTAGTIGANIGAGLATIFFLPFAACMLILAALAGVAIHKRRARRPVPTGPSPAAGPAAATPGPSTP

Crispr_ID: NC_017093_8

• CRISPR_ID: NC_017093_8
• CRISPR_location: 2539044-2539126
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_8

Consensus_repeat	Method
GGCGCTGAGTGCTGCCCGACCACGC	CRISPRCasFinder

spacers of NC_017093_8

>8.1|2539069|33|NC_017093|CRISPRCasFinder
TGCTGAGAGCACTGGACACCGGCCGGTCCGGCT

CRISPR arrays and Neighbor proteins around NC_017093_8

CRISPR arrays

The CRISPR arrays of NC_017093_8

>merge|NC_017093|8|2539044-2539126|CRISPRCasFinder
GGCGCTGAGTGCTGCCCGACCACGCTGCTGAGAGCACTGGACACCGGCCGGTCCGGCTGGTGCTGAGTGCTGCCCGACCACGC

>NC_017093|8|8|2539044-2539126|CRISPRCasFinder
GGCGCTGAGTGCTGCCCGACCACGC	TGCTGAGAGCACTGGACACCGGCCGGTCCGGCT
GGTGCTGAGTGCTGCCCGACCACGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_014442550.1|2546766_2547651_+|glucose-1-phosphate-thymidylyltransferase-RfbA	unknown	unknown	gnl|CDD|130274
NC_017093.1|WP_014442546.1|2542909_2544001_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NC_017093.1|WP_041830749.1|2530833_2532873_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014442544.1|2542123_2542369_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_172666579.1|2537801_2538458_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014442541.1|2538711_2538906_-|CsbD-family-protein	unknown	unknown	gnl|CDD|283241
NC_017093.1|WP_041830750.1|2534238_2534604_-|hypothetical-protein	unknown	unknown	gnl|CDD|211538
NC_017093.1|WP_014442532.1|2529962_2530679_+|hypothetical-protein	unknown	unknown	gnl|CDD|270970
NC_017093.1|WP_051041922.1|2535738_2537115_+|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|143635
NC_017093.1|WP_014442535.1|2533808_2534219_-|sulfurtransferase	unknown	unknown	gnl|CDD|236337
NC_017093.1|WP_014442543.1|2540514_2541975_-|glycosyltransferase-family-39-protein	unknown	unknown	gnl|CDD|227621
NC_017093.1|WP_014442534.1|2533079_2533766_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014442548.1|2544916_2545744_-|dTDP-4-dehydrorhamnose-reductase	unknown	unknown	gnl|CDD|367904
NC_017093.1|WP_014442545.1|2542362_2542920_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NC_017093.1|WP_157434824.1|2539321_2540356_-|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl|CDD|223131
NC_017093.1|WP_014442547.1|2544002_2544863_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381314
NC_017093.1|WP_014442549.1|2545743_2546721_-|dTDP-glucose-4,6-dehydratase	unknown	unknown	gnl|CDD|187557
NC_017093.1|WP_041829708.1|2537159_2537795_-|transcriptional-repressor-LexA	unknown	unknown	gnl|CDD|234688
NC_017093.1|WP_014442551.1|2547647_2548265_+|dTDP-4-dehydrorhamnose-3,5-epimerase-family-protein	unknown	unknown	gnl|CDD|376414
NC_017093.1|WP_014442537.1|2534651_2535707_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|197715

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_014442550.1|2546766_2547651_+|glucose-1-phosphate-thymidylyltransferase-RfbA	gnl|CDD|130274	TIGR01207, Glucose-1-phosphate_thymidylyltransferase_1, glucose-1-phosphate thymidylyltransferase, short form. Alternate name: dTDP-D-glucose synthase homotetramer This model describes a tightly conserved but broadly distributed subfamily (here designated as short form) of known and putative bacterial glucose-1-phosphate thymidylyltransferases. It is well characterized in several species as the first of four enzymes involved in the biosynthesis of dTDP-L-rhamnose, a cell wall constituent and a feedback inhibitor of the enzyme. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	1.11661e-162
NC_017093.1|WP_014442546.1|2542909_2544001_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	3.92615e-09
NC_017093.1|WP_014442547.1|2544002_2544863_-|aldo/keto-reductase	gnl|CDD|381314	cd19088, AKR_AKR13B1, AKR13B family of aldo-keto reductase (AKR). Xylella fastidiosa phenylacetaldehyde dehydrogenase is a founding member of aldo-keto reductase family 13 member B1 (AKR13B1). phenylacetaldehyde dehydrogenase (EC 1.2.1.39) catalyzes the NAD+-dependent oxidation of phenylactealdehyde to phenylacetic acid.	1.31509e-138
NC_017093.1|WP_014442541.1|2538711_2538906_-|CsbD-family-protein	gnl|CDD|283241	pfam05532, CsbD, CsbD-like. CsbD is a bacterial general stress response protein. It's expression is mediated by sigma-B, an alternative sigma factor. The role of CsbD in stress response is unclear.	1.08489e-06
NC_017093.1|WP_041830750.1|2534238_2534604_-|hypothetical-protein	gnl|CDD|211538	TIGR00026, Hypothetical_protein_Rv1261c/MT1299/Mb1292c., deazaflavin-dependent oxidoreductase, nitroreductase family. This model represents a family of proteins found in paralogous families in the genera Mycobacterium and Streptomyces. Seven members are in Mycobacterium tuberculosis. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. [Unknown function, Enzymes of unknown specificity].	0.000183779
NC_017093.1|WP_014442532.1|2529962_2530679_+|hypothetical-protein	gnl|CDD|270970	cd14068, STKc_LRRK2, Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 2. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. LRRK2 is one of two vertebrate LRRKs which show complementary expression in the brain. Mutations in LRRK2, found in the kinase, ROC-COR, and WD40 domains, are linked to both familial and sporadic forms of Parkinson's disease. The most prevalent mutation, G2019S located in the activation loop of the kinase domain, increases kinase activity. The R1441C/G mutations in the GTPase domain have also been reported to influence kinase activity. LRRKs are also classified as ROCO proteins because they contain a ROC (Ras of complex proteins)/GTPase domain followed by a COR (C-terminal of ROC) domain of unknown function. In addition, LRRKs contain a catalytic kinase domain and protein-protein interaction motifs including a WD40 domain, LRRs and ankyrin (ANK) repeats. LRRKs possess both GTPase and kinase activities, with the ROC domain acting as a molecular switch for the kinase domain, cycling between a GTP-bound state which drives kinase activity and a GDP-bound state which decreases the activity. The LRRK2 subfamily is part of a larger superfamily that includes the catalytic domains of other STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	0.0024474
NC_017093.1|WP_051041922.1|2535738_2537115_+|GGDEF-domain-containing-protein	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	4.23591e-45
NC_017093.1|WP_014442535.1|2533808_2534219_-|sulfurtransferase	gnl|CDD|236337	PRK08762, PRK08762, molybdopterin-synthase adenylyltransferase MoeB.	1.5951e-18
NC_017093.1|WP_014442543.1|2540514_2541975_-|glycosyltransferase-family-39-protein	gnl|CDD|227621	COG5305, COG5305, Predicted membrane protein [Function unknown].	1.67844e-20
NC_017093.1|WP_014442548.1|2544916_2545744_-|dTDP-4-dehydrorhamnose-reductase	gnl|CDD|367904	pfam04321, RmlD_sub_bind, RmlD substrate binding domain. L-rhamnose is a saccharide required for the virulence of some bacteria. Its precursor, dTDP-L-rhamnose, is synthesized by four different enzymes the final one of which is RmlD. The RmlD substrate binding domain is responsible for binding a sugar nucleotide.	6.99132e-101
NC_017093.1|WP_014442545.1|2542362_2542920_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	1.6388e-16
NC_017093.1|WP_157434824.1|2539321_2540356_-|cation-diffusion-facilitator-family-transporter	gnl|CDD|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	1.55526e-79
NC_017093.1|WP_014442549.1|2545743_2546721_-|dTDP-glucose-4,6-dehydratase	gnl|CDD|187557	cd05246, dTDP_GD_SDR_e, dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs. This subgroup contains dTDP-D-glucose 4,6-dehydratase and related proteins, members of the extended-SDR family, with the characteristic Rossmann fold core region, active site tetrad and NAD(P)-binding motif. dTDP-D-glucose 4,6-dehydratase is closely related to other sugar epimerases of the SDR family. dTDP-D-dlucose 4,6,-dehydratase catalyzes the second of four steps in the dTDP-L-rhamnose pathway (the dehydration of dTDP-D-glucose to dTDP-4-keto-6-deoxy-D-glucose) in the synthesis of L-rhamnose, a cell wall component of some pathogenic bacteria. In many gram negative bacteria, L-rhamnose is an important constituent of lipopoylsaccharide O-antigen. The larger N-terminal portion of dTDP-D-Glucose 4,6-dehydratase forms a Rossmann fold NAD-binding domain, while the C-terminus binds the sugar substrate. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	0
NC_017093.1|WP_041829708.1|2537159_2537795_-|transcriptional-repressor-LexA	gnl|CDD|234688	PRK00215, PRK00215, transcriptional repressor LexA.	3.33275e-93
NC_017093.1|WP_014442551.1|2547647_2548265_+|dTDP-4-dehydrorhamnose-3,5-epimerase-family-protein	gnl|CDD|376414	pfam00908, dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase. This family catalyze the isomerisation of dTDP-4-dehydro-6-deoxy -D-glucose with dTDP-4-dehydro-6-deoxy-L-mannose. The EC number of this enzyme is 5.1.3.13.	1.98061e-88
NC_017093.1|WP_014442537.1|2534651_2535707_-|alpha/beta-fold-hydrolase	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	5.7028e-20

Protein sequences

>NC_017093.1|WP_014442541.1|2538711_2538906_-|CsbD-family-protein
MAFDDKVDNKAEEIGGKVKEGVGRATDDEQLEAEGRADQTGSKFKQAGEKVKDAGEKVKDAFKS
>NC_017093.1|WP_172666579.1|2537801_2538458_-|hypothetical-protein
MMQKISRQAAVCAVAGGALTAVAGIVVQAVVVPNSTVSEQLWSYPWPSDQFTLVSILYAIFHVLVCVGMAGFARSGLAGDGRVARIGAWMAFGGTVVLFAAELASIPVGDQLIEERGPSAVGAMFGVGTVVAAIGFLLAGVTTLRAGRWQGWRRFTPLVAGLTLVAITGSVGTDVMSASIAAYGIGALGLGLAMLTQPDPRGVMTDQVSEPRRAPAGR
>NC_017093.1|WP_041829708.1|2537159_2537795_-|transcriptional-repressor-LexA
MAGVHLDTSLLSERQRRILTVIQEWAVRYGYPPSTRELGEALRLSPSTVSRHLRLLEEHGYLTRGRSMTRPIDVRMFLNTEVSEKEKDTIGVPLVGTIAAGTPIMAEETADEVLNLPRDLVGRGNLFSLRVQGDSMIDAAICDGDIVVVRQQPDAYNGDIVAAMIDEEATVKVFRRTRGHVLLEPRNPAYDVIDGDRATILGKVVSVLRRV
>NC_017093.1|WP_051041922.1|2535738_2537115_+|GGDEF-domain-containing-protein
MRAYFLLFAAAAMIAYAVAGDGRPVVQLIIVATPLATFLYALASRRLPHQRPWAIAVGGLIVLLIGQLWWPGWLDGHVGRAEGNPAELTLSAAHGLFLMGTAMALRRRLASDVGGLVDAALLGLCAGGPLWVWGVQPHLNPDASALGELLLMIDVFAICGVIGCLIRMGAARGPGRGTIVYLLCTAVLTLAALATGRPEPLLLAFLTIGAAPIQPFAASVTEPVADGAATSRVTLRWLAVALCVNPLLTVVQIMRGDESASLMLAVGTLLVIPLVLLRFHRLSMQREQAERTLAHQASHDELTGLRNRRHMMVAIDDALAGPDGATVLLCDLDGFKPINDRYGHAAGDEALTVVAARLLAVTREDDVVGRLGGDEFLVVCPSADAGDLAARIEETLCSPMALSVGMITIGVTVGVASVPAGSGLGREAVVARADAAMYAGKAPRRAGSSPAGAPLVLP
>NC_017093.1|WP_014442537.1|2534651_2535707_-|alpha/beta-fold-hydrolase
MRLDNQLVESLRFARADDGVTIGYQMFGQGPVLVWMPSLSNIVAQWRIPALRHAYRSLARKVTLILYDGRGTGSSDRRIDLDDLGVDAHLRDLHAVLAHAGVQRASLLGYYHSVTTAVAFAARHPERVDRLVLFGGSPRLRESMRPAQTQALLSLVDQDWGLFADAAATAWLGWDSAPSGRWTAEAFRTATTAAVAKAWFDAAARIDVTDELARVRAPALVLHRQGEQQIPAEVFRRLADALPDARLVERPGSTPTLFIEDAATDLRLVTEFVTGSPAPGAPVQRGLTPREREVLSLLAAGESNTEIARNLGIAVHTVERHLGSVYRKIGARGRTDAVIHALGLTENPHKR
>NC_017093.1|WP_041830750.1|2534238_2534604_-|hypothetical-protein
MNLVRATTPAVVTLAGRRWSPWAVVQHRGRVSGRDLEVPVVVIATPDSFVINLPWGARTNWVRNVLAAGGCTIRWKGSAHPADDPRVLGEAEARPYYSRVSWWIARRFFPADAWLLLHRAG
>NC_017093.1|WP_014442535.1|2533808_2534219_-|sulfurtransferase
MTTTIGGVDALLERARAGLRRLDPHETRAAVAAGALLIDTRTDRQRARQGELPGAIVIDRTVLEWRLDPRSESRIPEATGYDVHIVVVCRQGYSSSLAAAGLQAIGLRRATDLAGGVEAWLAAGLPTTTGPADVRE
>NC_017093.1|WP_014442534.1|2533079_2533766_+|hypothetical-protein
MVVPASGYIFTFQVHATFIWQSETLYRDQLTSAIDSLMPYAMRRLKARAARYSRRHQPHRAREFEVELQQVLRDEGAWDFNWYGEDLTCQPHIWVELDEQVKQAVRPYGEELIKLDCEHDVQMRRAEYSEKLSKQWASILTGLMGSPVADGAAEMTEKELADVVRKILAEQKAAADKLEDLMAKKVDDGDAYERSDHFEKLRERLERRADRLFAPTDGGSPNGHGAPE
>NC_017093.1|WP_041830749.1|2530833_2532873_+|hypothetical-protein
MSSLGSEAGESDEAGPIDPDSLRLDQRVAREMFGDLFTGIVSSAPAQFGSHNEMHNYLGRRPLDPIVASLPDVDGLMSVYVRTDSDGDLDRLLSQRHTACLAGARNSGRYSAAQVALSRRHDPARVYEIVLPTDVSPEVLVSKPDKLPVDSGFVLRLPGTGHVDAMRKLAALFRGRSSTLLLIKEEETARGDRPGAEMRHAPPDPIEVFRSHLAREMRDEGPTTLERYQNEEVEAAVKATYGPKECVAIARAIAHERPVGAEALRALLERSQPKRRERAAEVLLPDADRSSGRNRRAGQHERAFRLSYAVFYHRPMHYVFEAADWLLREIDSAALRPDWGSMALQYPVTDLLGDALKRDWEEGREAGVATLGASRIAWIRDGGLRGAIIDVAWHEFDGTRRSLLRWLDRLVVEGDEVMQRAAAETAGLLTHYDFARIHEDLVDKWAASPKQEVRQVAAWTMTLSDMAGDVGPMVRKKLSEWCSGSSNYQRDTAARVYASGLQQTVLAWSMYDLARIARNKYQKRRYAVAEAVNQLYSPDRAAWIVAELADWARDPLLQVHAARALLVLAAQVEHGSSDGQPDVLLRLAEGSVELRHLSALWLVAFLDPTTAVEAGRTLARWIRHADANDEFRDDIIALLESIRVSRNTALQRITFYLSRHSGFGDGLPDWMTTERRKVP
>NC_017093.1|WP_014442532.1|2529962_2530679_+|hypothetical-protein
MQDPHRRVLVAADMESYSGRNNVLQYRAQIAFRQIMGDAAAQAGLDRIDWLIQQGGDGELAILPSGTSERTVVARLAPTVDRLLREHNQGLTATARIRLRLAVHQGLVHLDGANGFPSDAVVHVCRLIDSPQLKKALRAFPDANVALAVSDSLYHEVVEHYRDLRPEQFGEVRAEIPDKGFSATAWIYVPGENVRGAPPEPDMPTPTPTPTAGQTFSGITTHGPAQFGNHNEMRNSDG
>NC_017093.1|WP_157434824.1|2539321_2540356_-|cation-diffusion-facilitator-family-transporter
MVCAVDHHEHDHSAHHRLRHLLTPHSHDTADKVDNALESSREGLRALWISLAGLGVTAGLQALIVALSGSVALLGDTVHNVADALTAVPLAIAFWLGRRAATRAYTYGYGRAEDLAGVLIVAVIAASAVTSAWFAVDRLLDPRTVTHLPWVAAAGLVGFAGNEVVARYRITVGRRIGSAALVADGLHARTDGFTSLAVVLAAGGAWLGWSWADPAIGLAITVAIILVLKDAAREVYHRLMDRVDPALVDQAERALRSITGIRGVSGLRLRWIGHHLHAEAGIVVDARLSLMAAHEIAADAEHQLTHRVPRLTGATVHVDPDSHPGDDHHSALSHGRRERLTTLP
>NC_017093.1|WP_014442543.1|2540514_2541975_-|glycosyltransferase-family-39-protein
MKIQNHFPVRLRLAAAPILLTLTVCLVGIGQRQFWRDEQATWWASALPFGDLRRLIEQVDLVLLPYYLFMHVWIAIFGNSETAMRVPSAILMGVAAGLLALVGRRLLDAPTGLLAGLLFALVPAVSRYGGEARPYAAALAATLGATLLLLRARDKPSPWRWALYGVSVICIGLGHLVSLSVLAAHLALVIAAARTDRRVRIGWAASVTTALVVLAPVILISRRQSGQIAWIEEPTWEVLRAFPGEVFVSGPVAALVLISGLIGIGLLLTSNRTAATTLLLWTLLPPVLAYLSFDVLGLFYHRYFLFTVPAWLLAAAWALRRIFTTRRALVAAGVCAALALVATGLPQQRFVRSNAVEDEYAWKDAARWLDERLQPGDRVAYTGYVRLHRGFSYEFSRLPGTDPGEVYSRVTRHGDWWWEHDLAADPEAALTGVDRFWLVEANPRTGPLGRLRAGARAYVSEHYTVAETGSFHHLRVTLLTRHAISP
>NC_017093.1|WP_014442544.1|2542123_2542369_+|hypothetical-protein
MEIWDPLAGALVTQLINVMVAALCGVRFRRSDAADLADPTDPPDERWVEVRMSWCRGRSGEQPGPGECPGHDESGPDERPW
>NC_017093.1|WP_014442545.1|2542362_2542920_+|sigma-70-family-RNA-polymerase-sigma-factor
MVTQTAAAIPEKRDDDPLGADFQDFYREVAPGFHRRALARGLSEHDAHDVVQDVMLKILGRWRKVGALSPGERFGYADRALRHAITDVWRRQQRDAALGMRLRQESVDRGDPAERDSAGAEALRLVGTLTGCQYQVMVLAQEGLKPREIAAELGMRNSTVSSHLHEARRKLMTKLQAWKDSGREE
>NC_017093.1|WP_014442546.1|2542909_2544001_+|hypothetical-protein
MKNEPLLTTDEHELLRRAQDEALAGTAFDVEAGLADLRERARRPAAVPARQRVEWRERFRLRVGTTAGLAALLAALTGGGLGVVAMQARTENPQVRVPDVPAQPIIPAATPSARTHGTGHDRPATPPRDHHQDHIPGGTPPRTSPATRATVAPPIAEPPAGDSPATGPTGAPTAAAASPAATPPATPAGDAVPSPTGAAAGPPTGGAAGPPTGAAGGPPTGAATAGDPEPFAVHYAAMSLTVPVDDEEPQAIDLAEPRTSPGGAGAVAISAVPDTGDLMLEPTSDVQAATISTAAATPDECAAAIRDDPAGDAPLKLRDDRTYCLLTPGEQADGDTLVQLTVDEKDDDAGEVVVHLAAWNVAA
>NC_017093.1|WP_014442547.1|2544002_2544863_-|aldo/keto-reductase
MTLSNSGTIALGGRNVHRLGFGAMRITGPGVWGPPRDPAAAVAVLRRSVELGVTFIDTADSYGPDVSENLIHEALHDGTGYGDVVIATKGGFTRQGPNIWQAVGRPEYLRQCILMSMRRLGVEQIDLWQLHRIDPLVPRDEQFGVLRSFVDEGLAKQVGLSEVSVDEVKAAQAAGVPVASVQNRYNLGDRRAEELLDYCTEQGIAFIPWAPVDAGALARPGGPLESVARAHPGTTTGQLALAWLLQRSPVMVPIPGTSSVAHLEENLAAADVKLTEDEYQTLAKAV
>NC_017093.1|WP_014442548.1|2544916_2545744_-|dTDP-4-dehydrorhamnose-reductase
MRWLITGAGGMLGQDLQKVLKGDDVVALGRADLDITDPAAVRAATDGADVVINAAAWTDVDGAESNEEAATAVNGHAVAGLAAVLGDRLIHISTDYVFDGTATSPIPEETPQAPLNAYGRGKAVGEKAVLAAGGYVVRTAWLYGEHGPNFVRTMLRLATERDTVDVVDDQVGPPTWSFALAQQLVALGRSDAAPGAYHGTAAGSTTWFGLARAAFALAGHDPDRVRPTTSDRFVRPARRPAYSVLGHDRWQAGAGVDPLPDWHAMLTEAMPALRA
>NC_017093.1|WP_014442549.1|2545743_2546721_-|dTDP-glucose-4,6-dehydratase
MQIFVTGGAGFIGSAYVRALLQDEYAGAAGASVTVLDLLSYSGNRENLPVSDPRLNFVQGDITDSNLLHDLLPGHDVVVHFAAESHVDRSINSAVPFVTTNVLGTQVLLDAARAAGVGRFLHVSTDEVYGSIDEGSWTESWPLAPNSPYAASKAASDLMALAAHRTHGMDVVVTRCSNNYGHHQFPEKVIPLFVTNLLDGKKVPLYGDGGNVRDWLHVSDHCRGIQLALEKGRAGEVYNIGGGTELSNRELTERLLTACGADWDSVELVTDRKGHDRRYSLDISKISTELGYEPQVTLDDGLAATVAWYRDNRGWWEPLKSRSAL
>NC_017093.1|WP_014442550.1|2546766_2547651_+|glucose-1-phosphate-thymidylyltransferase-RfbA
MRGILLAGGTGSRLWPITKAMSKQLMPIFDKPMIYYPLTTLVSAGIREILVITTPEDQPHFERLLGDGKQFGLSLTYAQQPKPDGIAQAFRIGADFIGDEPVALILGDNIFHGVGLGRQLARFGEPAGGRVFAYPVADPERYGVVEFDESGKVLSIEEKPERPKSTYVVPGLYFYDADVVEIAGDLKPSARGELEITAVNEEYLRQGRLDVTVLDRGTVWLDTGTFQSMVQASEYVRVIEERQGLKIGCVEEAAWRLGFISDDQLRELAEPLLKSGYGEYLVRLLSAGRFGGVL
>NC_017093.1|WP_014442551.1|2547647_2548265_+|dTDP-4-dehydrorhamnose-3,5-epimerase-family-protein
MKISPLGIEGAFEITPVQHGDARGSFLEWYRFDHLAEAVGHPLDLAQGNLSVSARDVVRGIHFADVPPGQAKYVTCVKGAVLDVIVDIRVGSPTFGRWESVRLDDEDRKAVYLGEGLGHGFCALTEGATVAYLCSTEYRPGREHGIHPLDPTLGIAWPAETPLLSGKDAQAPSLEEARDKGLLPRYEECQNYAESLRRNHYSRTS

Crispr_ID: NC_017093_9

• CRISPR_ID: NC_017093_9
• CRISPR_location: 3315002-3315091
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_9

Consensus_repeat	Method
GGCCCTGCGCTGAGCGTCCGGGGCGGGG	CRISPRCasFinder

spacers of NC_017093_9

>9.1|3315030|34|NC_017093|CRISPRCasFinder
CTCAGCCGCGTGGTGTCAGCGGAAGGCCGCCTTC

CRISPR arrays and Neighbor proteins around NC_017093_9

CRISPR arrays

The CRISPR arrays of NC_017093_9

>merge|NC_017093|9|3315002-3315091|CRISPRCasFinder
GGCCCTGCGCTGAGCGTCCGGGGCGGGGCTCAGCCGCGTGGTGTCAGCGGAAGGCCGCCTTCGGCCCTGCGCTGAGCGTCGGGGGCGGGG

>NC_017093|9|9|3315002-3315091|CRISPRCasFinder
GGCCCTGCGCTGAGCGTCCGGGGCGGGG	CTCAGCCGCGTGGTGTCAGCGGAAGGCCGCCTTC
GGCCCTGCGCTGAGCGTCGGGGGCGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_014443271.1|3312220_3312874_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NC_017093.1|WP_014443268.1|3310168_3311029_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|375319
NC_017093.1|WP_083888808.1|3318091_3319093_-|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|234629
NC_017093.1|WP_014443281.1|3321044_3321638_+|dihydrofolate-reductase-family-protein	unknown	unknown	gnl|CDD|223340
NC_017093.1|WP_014443267.1|3309829_3310159_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NC_017093.1|WP_014443270.1|3311957_3312224_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014443276.1|3316354_3316915_-|dihydrofolate-reductase-family-protein	unknown	unknown	gnl|CDD|334719
NC_017093.1|WP_157434879.1|3316994_3318059_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014443279.1|3319202_3320189_+|formylglycine-generating-enzyme-family-protein	unknown	unknown	gnl|CDD|335469
NC_017093.1|WP_157434880.1|3327196_3329476_-|hypothetical-protein	unknown	unknown	gnl|CDD|197715
NC_017093.1|WP_014443269.1|3311175_3311973_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|235546
NC_017093.1|WP_014443283.1|3324480_3327204_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197715
NC_017093.1|WP_041829805.1|3320119_3320968_-|hypothetical-protein	unknown	unknown	gnl|CDD|368060
NC_017093.1|WP_014443275.1|3315765_3316338_+|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl|CDD|274926
NC_017093.1|WP_083888640.1|3309404_3309833_+|ATP-binding-protein	unknown	unknown	gnl|CDD|340413
NC_017093.1|WP_014443264.1|3307420_3308404_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_051042012.1|3306443_3307433_-|DUF1152-domain-containing-protein	unknown	unknown	gnl|CDD|377680
NC_017093.1|WP_014443265.1|3308634_3309249_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014443274.1|3315105_3315546_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014443272.1|3312952_3313909_+|zinc-binding-dehydrogenase	unknown	unknown	gnl|CDD|176206

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_014443271.1|3312220_3312874_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.29528e-06
NC_017093.1|WP_014443268.1|3310168_3311029_-|helix-turn-helix-domain-containing-protein	gnl|CDD|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	1.07378e-45
NC_017093.1|WP_083888808.1|3318091_3319093_-|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	gnl|CDD|234629	PRK00094, gpsA, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.	1.14691e-154
NC_017093.1|WP_014443281.1|3321044_3321638_+|dihydrofolate-reductase-family-protein	gnl|CDD|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	1.03723e-05
NC_017093.1|WP_014443267.1|3309829_3310159_+|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	2.27758e-21
NC_017093.1|WP_014443276.1|3316354_3316915_-|dihydrofolate-reductase-family-protein	gnl|CDD|334719	pfam01872, RibD_C, RibD C-terminal domain. The function of this domain is not known, but it is thought to be involved in riboflavin biosynthesis. This domain is found in the C-terminus of RibD/RibG, in combination with pfam00383, as well as in isolation in some archaebacterial proteins. This family appears to be related to pfam00186.	9.96414e-16
NC_017093.1|WP_014443279.1|3319202_3320189_+|formylglycine-generating-enzyme-family-protein	gnl|CDD|335469	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1. This domain is found in eukaryotic proteins required for post-translational sulfatase modification (SUMF1). These proteins are associated with the rare disorder multiple sulfatase deficiency (MSD). The protein product of the SUMF1 gene is FGE, formylglycine (FGly),-generating enzyme, which is a sulfatase. Sulfatases are enzymes essential for degradation and remodelling of sulfate esters, and formylglycine (FGly), the key catalytic in the active site, is unique to sulfatases. FGE is localized to the endoplasmic reticulum (ER) and interacts with and modifies the unfolded form of newly synthesized sulfatases. FGE is a single-domain monomer with a surprising paucity of secondary structure that adopts a unique fold which is stabilized by two Ca2+ ions. The effect of all mutations found in MSD patients is explained by the FGE structure, providing a molecular basis for MSD. A redox-active disulfide bond is present in the active site of FGE. An oxidized cysteine residue, possibly cysteine sulfenic acid, has been detected that may allow formulation of a structure-based mechanism for FGly formation from cysteine residues in all sulfatases. In Mycobacteria and Treponema denticola this enzyme functions as an iron(II)-dependent oxidoreductase.	2.56221e-79
NC_017093.1|WP_157434880.1|3327196_3329476_-|hypothetical-protein	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	6.14182e-15
NC_017093.1|WP_014443269.1|3311175_3311973_+|SDR-family-oxidoreductase	gnl|CDD|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	2.62506e-73
NC_017093.1|WP_014443283.1|3324480_3327204_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	3.0644e-17
NC_017093.1|WP_041829805.1|3320119_3320968_-|hypothetical-protein	gnl|CDD|368060	pfam04695, Pex14_N, Peroxisomal membrane anchor protein (Pex14p) conserved region. Family of peroxisomal membrane anchor proteins which bind the PTS1 (peroxisomal targeting signal) receptor and are required for the import of PTS1-containing proteins into peroxisomes. Loss of functional Pex14p results in defects in both the PTS1 and PTS2-dependent import pathways. Deletion analysis of this conserved region implicates it in selective peroxisome degradation. In the majority of members this region is situated at the N-terminus of the protein.	0.00152475
NC_017093.1|WP_014443275.1|3315765_3316338_+|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl|CDD|274926	TIGR04025, hypothetical_protein, PPOX class probable FMN-dependent enzyme, DR_2398 family. Members of the PPOX family (see pfam01243) may contain either FMN or F420 as cofactor. This subfamily consists of proteins mostly from species that lack the capability to synthesize F420, and therefore most likely all bind FMN.	2.63831e-12
NC_017093.1|WP_083888640.1|3309404_3309833_+|ATP-binding-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	1.60656e-16
NC_017093.1|WP_051042012.1|3306443_3307433_-|DUF1152-domain-containing-protein	gnl|CDD|377680	pfam06626, DUF1152, Protein of unknown function (DUF1152). This family consists of several hypothetical archaeal proteins of unknown function.	4.37994e-18
NC_017093.1|WP_014443272.1|3312952_3313909_+|zinc-binding-dehydrogenase	gnl|CDD|176206	cd08244, MDR_enoyl_red, Possible enoyl reductase. Member identified as possible enoyl reductase of the MDR family. 2-enoyl thioester reductase (ETR) catalyzes the NADPH-dependent dependent conversion of trans-2-enoyl acyl carrier protein/coenzyme A (ACP/CoA) to acyl-(ACP/CoA) in fatty acid synthesis. 2-enoyl thioester reductase activity has been linked in Candida tropicalis as essential in maintaining mitiochondrial respiratory function. This ETR family is a part of the medium chain dehydrogenase/reductase family, but lack the zinc coordination sites characteristic of the alcohol dehydrogenases in this family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. Candida tropicalis enoyl thioester reductase (Etr1p) catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis. Etr1p forms homodimers, with each subunit containing a nucleotide-binding Rossmann fold domain and a catalytic domain.	4.57668e-89

Protein sequences

>NC_017093.1|WP_014443272.1|3312952_3313909_+|zinc-binding-dehydrogenase
MRAVWLTAFGPPSLLQVRDRPDPVAGPGEVLIAVEFAGITWIETMFRATGFGPFPAPPMIPGNGVAGTVLAAGSADVRHLVGRRVVTGTGGSGGYAELVAVDAGQVIEVPAGVATEDAAALLADGRTALMIMEAAAVRSGDRVLIEAAAGGVGSLLVQRAVAAGAEVVAVAGTARKLEVARGLGARHTVDYLEPGWPEAVRAAAGEVDVVLDGVGGAVAETAFDLLVTGGRMISFGFSGSTGWPDISDEAAEQRGIRMQRGVFASPEDQRRHTVAALDLAAAGALRAVVGQRFPLEQAAQAHAAMESRAAVGKTLLKA
>NC_017093.1|WP_014443271.1|3312220_3312874_-|TetR/AcrR-family-transcriptional-regulator
MISGPRTSGPRTSDPRGRRAEYAQLTRQAILEAARDLFVSQGYFETRVEEIAAVARVAPATVYAVGGGKNGLLRTLIADGTAGQDVAQVIARIEAITDPAELLRFIAHATRATFEQWSALMRQVVAAAPREPGVRETLDIAHDSMRGGFRLAADRLAALGGLRDGVDAARAADILWLHLCNAAYFIRTDDLGWSLDESETWATEALTTALLTERGTR
>NC_017093.1|WP_014443270.1|3311957_3312224_-|hypothetical-protein
MITVAVAVGVAGVLLLLAAAALRRRRAAAAPLPPVDPETLRAEIAQELARSGGVAAIKRYRQRTGASLAEAKAAVDRISRGPGDHRPT
>NC_017093.1|WP_014443269.1|3311175_3311973_+|SDR-family-oxidoreductase
MTVNPNHHPAPITIEGRRLQGRVILITGASAGMGAAATRRFAAEGAHVIAGARRTDRLAELAAELSTGDNEVVAVPLDVTDEASVEAAVALAVTRFGRLDGALNAAGVTSDGTPVHQKATATYDRVMDINAKGVFLSMKHEIPAMLAAGGGSIVNVSSIGGMVGVAGISEYVASKWAVNGLTKSAALELAPFGVRVNALAPGSTRTEMWDQLPVDFQMHLAAMAPMNQIALPDDMARAALFLLSDESRWTTGAVLPAEGGHHVGR
>NC_017093.1|WP_014443268.1|3310168_3311029_-|helix-turn-helix-domain-containing-protein
MSHHEMARCLRAWRDRLTPASAGLPSGALRRAPGLRREEVAHLAGLSVDYLARLEQGRAGNPSPSVLESLGRALRLSDDENAHLFQLAGHANPRSAGVNRHLTPGVQRMLDRLGDVPVMVLDAAWQLVALNPLCAALLGDLNGESGRRRNLLWRHFTGVASRVVSTPETDAAFEAAAVADLRAAAGRHRHDRNLRALIAELRQSSPRFAELWQRGAVARHASTRKTIRHPQVGQLTLDCDVLTVEGSDLRIVVYTADPGSPDARTLALLGAIGMHSFPGDVVTSGA
>NC_017093.1|WP_014443267.1|3309829_3310159_+|STAS-domain-containing-protein
MKITSQYADGVTRLLVSGELDMSTAPDLHDHVAAALAGAEPRTLVIDAVDLDFCDSSGIQALVQTHRRVTQRGIAFRLTNAHGVTRRTLQLTGVLDVLTGGPGDGERIR
>NC_017093.1|WP_083888640.1|3309404_3309833_+|ATP-binding-protein
MTTLTAHFDVPIGPDSPRTARKAVVSVLQVWGYADEGWAADVAVVVSELVTNAVQHGAGSVVLEIEAYGDQVIVSVADGSSVVPRRREPDGRGGRGLALIEALTRRWHVEEHQGGKRVRAEIQGYPDPWGPATETGSGREHP
>NC_017093.1|WP_014443265.1|3308634_3309249_-|hypothetical-protein
MIVVVTGPSAAGKTTWCRRHVPDDTVPEHVPDPGETPGPDPAGQAAFWCEAGARRWRQAERQERRSGLAVCDDDPLKLHYAWSLARIGELSWPHWRAEVDAHRTAVAAGRLGFADLVLVSAPPEDELRRRRDADPTRRRRNFDLHVRLAGPLREWYRAVERAGAAHVVWELPPAGLPAELPPPRAGRCDAEAFDAVIAALPEAS
>NC_017093.1|WP_014443264.1|3307420_3308404_-|hypothetical-protein
MFGRFRRTFTPDTDYAQADLQLRDARSRATSGDWNAASQLMHATGRDWELRSRRLAVLGIAAGHAPQWVDAWETAIPGDPTVAILRAEGLLELAGRARGAASARNTTPEQFQEFHRLAALAADASERAVTLNPEDPYPWVLRMDSMLANGYQHRDDFPVALGEAVARDPHHFEAHLTAVTFLCQKWYGSHEEMFVAARGPATAAPAGASVVLLPLLAHFEYALREFGFETRAESLAAKKEYFHRPEVIEEITWCATKWRAAGEPRLTGRGITLRHWLALANHLSDRDREGTRALLTQIGSYLGSTPAYGYFWMRQADGFHAVTKWAR
>NC_017093.1|WP_051042012.1|3306443_3307433_-|DUF1152-domain-containing-protein
MGPIVASTPPASSPLDTPPLFAALHGARSVLLAGAGGGFDVYAALPLAIALWNRGVTVHLANLSFTPLEMLDLNVWTAPDVAVVRPETAGPEEYFPERTLARWLAAHDLPATVYAFARTGVQPLRAAYRHLAGELGIDAIVLIDGGTDILMRGDESGLGTPAEDITSLAAVAGLDVPVKLVSCLGFGIDAYHGVVHSQVLENLAALDRDGGYLGMLSIPGAGREAVLYRDAVADAHRATPMRPSIVQGQIAAATRGDFGDVQFTRRTAGSTLFVNPLMAAYFTVDLVMLAGRCLYLDRIEQTVGMRQVATRIEAFREDITFRTPRAFPH
>NC_017093.1|WP_014443274.1|3315105_3315546_+|hypothetical-protein
MGSLDEVAKRDGWRCWVCDEPVDPDMSVNDPRGPSVDSRTADRKAKIAERLAHRACNTRKGAVKVVIAWPERLNVVEPAPLITVAERLERKGGRELVARCPSKRDAQEAADWLVDRFSRLVPGLPVTATVDAGGGQFLVALSTGRR
>NC_017093.1|WP_014443275.1|3315765_3316338_+|pyridoxamine-5'-phosphate-oxidase-family-protein
MKVHERIDGRLRAFIEAQPMFFVATAPTGPGGHVNVSPKGMGGTFAVLGEHRVAYLDYHGSGAETTAHLSENGRITLMFCAFQGPPNIVRLHGRGRAVPVTEPEFPELLRLFGAAPDTHGVRSVIDVAVDRVSDSCGYAVPLMSYEGDRDLLLRSHGRRTDADLAEYRRVKNGHSIDGRPVFAEAAATDG
>NC_017093.1|WP_014443276.1|3316354_3316915_-|dihydrofolate-reductase-family-protein
MAKLINIDIVSLDGRVNDENGKFGWAEPIEEVHRFMNDLDREIGTHLYGRRLYEVMSFWETAHEDPAAPDYVLDYSEIWRSSDKIVYSSTLTEPRTARTRIEPTFDPEAVRALKESSTRDLAIGGATLAGEAYRAGLIDEVGLLICPVIVGGGTRALQGGVRRDLTLIDQRTFSKGTIFARYRVDG
>NC_017093.1|WP_157434879.1|3316994_3318059_-|hypothetical-protein
MSAGVAVVFLAVVAARFLLPLAIPYFPLPAVIACLVLDGVDQTIFQTFGYDPPGYQSYDKAMDVYYLAIAYLSTLRNWTSEAAFRISRFLFFYRLAGALIFELTQARWLLLVFPNVFEYFFIGYETIRSRWSPVTVLTTWWLSLAGIIWVVVKLPQEWWLHVAQLDLTDEIAAHRWILGLIVALVAGLAVTFQRLLRPRLRPADWGWRFRPEPLPEQIDEPHEQSAWRIRNDRVLSWNTAEKALLLGLICCVFGQMLPDFTGSTGELFLGVGVTVVLNAAISLAVARRSWTIRSTALAFAARLVLNIVLSVVANALLGLRIDGYETLFFLTMISLITTLHDRWRPVHEFRVRAA
>NC_017093.1|WP_083888808.1|3318091_3319093_-|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase
MRITVLGAGSWGTTVASVLTRRDHESLIWARNPATADEINAKHTNERYLAGFPLPDRLRATADLAEAAAHAELLVVGVPTGAFRTTLELVRPDLHPWIPVVSLSKGLERDSLSRMTEVIKEVLPGHPAAALTGPNLAKEIMAGMAAATVIATEDLTVATEIQRVFRRGLLRVYTNHDVIGCEVGGALKNVVAIATGIAQGLGVGDNTRAGVISRGLAELTTLAVAMGGEPTTLAGLAGMGDLVATCISPHSRNRHVGEQLGRGRGLDDILAEMGQVAEGVKTVHAAVRLADRHGLAMPITRTIHRVVTGEITAARAYDGLLRTHPAGHESDPG
>NC_017093.1|WP_014443279.1|3319202_3320189_+|formylglycine-generating-enzyme-family-protein
MTEPEPGACCSPARAGGASAVPRTVVLTPGRPDTGDMIELGGGRFLMGTDDADGFPADGEGPVRAVTVSPFRIAPVAVTNARFAEFVADTGYATEAERAGWSFVFAGLLPDDFPPTRGVRAAPWWRQVEGADWRHPEGPQSAVGDRADHPVVHVAHTDAVAYCRWAGVRLPTEAEWEFAARGGLEQARFPWGDEPPQGRCNIWEGTFPGRHTGSPGTAPVRSYQPNGYGLYDMAGNVWEWCSDWFSPAYHRDGPRADPAGPPTGTARVIRGGSYLCHESYCNRYRVAARNQNTPDSSTGNTGFRVAQPFVSISARMSGKSPFTSTAVS
>NC_017093.1|WP_041829805.1|3320119_3320968_-|hypothetical-protein
MTYPPPVDPFETPQHTQPLFEQPDYGRPGAQPGPHQAGPHQAGPAHPGYLPPTYPMAPVPPPPPPPARSRTAAIVLLSVAIALVLLVGGGTVSYLAGKKLNSKDGTAQRESTAPSPSVESAAPSASVARPEDTITISEPDTLNGHDKIEAEELSSLTRDLEKEVEGYPGADNAFGAAYGALGEKKLIAALAAEVDIDDPQGMLDTMFQSFSGESQLTGVSPASTGALGGVAQCGDSVIGKENVALCGWADEGSVGMFLFFYETAVDVKGDFPDMRAEIETKG
>NC_017093.1|WP_014443281.1|3321044_3321638_+|dihydrofolate-reductase-family-protein
MARVIMQAVVSVDGYIAYPDDSVGPLFDWYGNGDVTIHANEKWSFRVSRASADYVTPFWDAIRCTVIGRHLFDITDGWQGVPAAGEHVVVVTHRPLPEEWLARFPDAPFHPAGSVEAAIELAAELARDGLVCVPAGDVGGQVFAAGLVDEVAMDVAPVVLGEGVRFFGSHTGTVLLDDPDTVVQGDRVLHLHYTVKR
>NC_017093.1|WP_014443283.1|3324480_3327204_+|helix-turn-helix-transcriptional-regulator
MHPVTSSPPGHQLIGRDTELARIEQFLGADSACCGTLVITGDRGSGKSALLSAGTTRAVGPRGRRLVRVQHREHAAFDPMRQMLLAVRHDLVALEPAISEPALALLGLAPGTPPADGDLPSLVAAAFPAIAARSPLLIVADDLHDAGDAFAGLLSRLSAAPGTAVLVTSRMPIPPALTGMPVIVLNPLPGDAAERLLADRRPTLTAAARTRVLHRAGGNPAALLELGVVSPPPEGLLAEYVEALAGLPGDTRARLLRGAALGPAHLDLLDAGGHRDGGTDAGTDAAWYPALRAGLITCTGDDVAFAHPLVAEAAYRSAPAYLRLRTHRDLAVALTGHPEHQALQRAAAEPDANEETAAALETAAAIFRGRGDRYAAGVAMHEASLRSPSRQSAARRLTQAIIDARDLRDSAWVAELHARIWHLTDDPDVLAVAAAPAATAMLWAGRYHDAYGIVLAVHHAGRPADRRHALQLTVAAALIAWLTCDEEHLTGLGPMLGAAEPAPDQVAAALVRTLIDPHAHPGREICAAASLPPAGTPLSPEARSRMAHLGMLAWLEDHCRLAVRALQHALADDVAGDLIVRQSSPTLGLLLSRASALIDIGDWRLADVCASPRLAHGMPAVELGFASLRAQLHALRGENEQALTLARQTWQQLDLRANLPAHVRLLRAAGLASIGNGDHDDGYRYLRSMFDVNGRPLHPYLSSRCVADFVVAAVRCGRDEQARMVVDRVRETAGPQPGARMSILLHLSEAMLAGPDRAEEHFRLAAYDPAGPEWPYEHAVAHLHYGFWLRRHRSPREAKALLAHAAYIFTALGAADAGAAEHEIVVGARPHQRDGGFDVDALTTQERQVAELAARGLVNRAIAEQLFLSVRTVSTHLSRIYRKMGIRGRHELATALFAGSAAEGDLS
>NC_017093.1|WP_157434880.1|3327196_3329476_-|hypothetical-protein
MARRLDDDALTTLVGLSALPAVTVIVAARAPLPAALRGQPRLELAPLPPADAVRLLDAGAPHLTAGVRASILHRAQGNPAALLELAAPDVPSGSLLSAFAAALGSLTERERTMLLHLAAAGRPVDPALLPVTGVPDPDPALAPAPAPAQAQAQAQAQAQAPASLVRHTPEGLAFVHPLAAEAVLRTATAGTLRRAHQRLAATVAAYPEWQALHLAAADPHPGETIAARLEAAASVFRDRGDRYRAADAMRQAADLSPDPTSAARRLTRAIADARDLRDATWAADLHARVWNLTGDPDVLAEATRPAATALLYADRQHQAYGMIMAAHRAGPATDPAAALILAMIATGVADSTGDDDHRQGLTALLAAAEPVPEPSIAAYVRELIDPGAHPGRDLCDTAVVPAPDTELDPRTWHRLTELGMIAWFEDHSELAARLLLRAIGDTPPPLPAPTFHTLPALTGTLIDIGDWARADVFADERWAAGWPMMRANLAAVRAQLLALRGHGDDALRLARTTWQGLDVHGNRAAHIRLLRAAALAAAAGGGHDDAYRYLRSMFDRDGRPLHPHLSPRCVAEFTVAAVRGGHHDAAGLVVEQVRRTAGAEPSARMRILLRLSDALLGDSEADFRAAVTDPAAPRWPYEHAYANLQYGLWLRRNRSPREARTLLARAAADFTRLGAPGPAAIAEREIAVGAQPATAARHAVATHLTTQERQVAELAAQGLSNRAIADRLLISARTVNTHLTRVYRKAGLEGRHQLWSAFS

Crispr_ID: NC_017093_10

• CRISPR_ID: NC_017093_10
• CRISPR_location: 3799957-3800093
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_017093_10

Consensus_repeat	Method
GCCCCGGATGTCGGTGCCGCCCCGGATGT	CRISPRCasFinder

spacers of NC_017093_10

>10.1|3799986|25|NC_017093|CRISPRCasFinder
GGGCGCCGTGCCGAACCCGGGCCCT
>10.2|3800040|25|NC_017093|CRISPRCasFinder
CGGTGCCGCCCCGGATGTCGGTGCC

CRISPR arrays and Neighbor proteins around NC_017093_10

CRISPR arrays

The CRISPR arrays of NC_017093_10

>merge|NC_017093|10|3799957-3800093|CRISPRCasFinder
GTGTCGGGCGTGGGTGCTGCGCCTGATGTGGGCGCCGTGCCGAACCCGGGCCCTGCCCCGGATGTCGGTGCCGCCCCGGATGTCGGTGCCGCCCCGGATGTCGGTGCCGCCCCGGATGTCGGTGCCGCCCCGGATGT

>NC_017093|10|10|3799957-3800093|CRISPRCasFinder
GTGTCGGGCGTGGGTGCTGCGCCTGATGT	GGGCGCCGTGCCGAACCCGGGCCCT
GCCCCGGATGTCGGTGCCGCCCCGGATGT	CGGTGCCGCCCCGGATGTCGGTGCC
GCCCCGGATGTCGGTGCCGCCCCGGATGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_172666599.1|3803616_3804243_-|hypothetical-protein	unknown	unknown	gnl|CDD|236766
NC_017093.1|WP_014443755.1|3806060_3806483_+|universal-stress-protein	unknown	unknown	gnl|CDD|238182
NC_017093.1|WP_014443750.1|3797082_3798450_-|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|235917
NC_017093.1|WP_157435353.1|3808483_3809152_-|class-F-sortase	unknown	unknown	gnl|CDD|320678
NC_017093.1|WP_014443758.1|3809256_3809829_-|hypothetical-protein	unknown	unknown	gnl|CDD|164795
NC_017093.1|WP_014443748.1|3795617_3796130_+|SigE-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|132028
NC_017093.1|WP_014443745.1|3791975_3792602_-|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NC_017093.1|WP_014443740.1|3788479_3788908_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014443741.1|3789095_3789491_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_157435352.1|3793727_3794618_-|phosphotransferase	unknown	unknown	gnl|CDD|270702
NC_017093.1|WP_014443749.1|3796135_3797086_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014443743.1|3790278_3791271_+|IS481-family-transposase	unknown	unknown	gnl|CDD|366234
NC_017093.1|WP_014443756.1|3806473_3808303_-|hypothetical-protein	unknown	unknown	gnl|CDD|378931
NC_017093.1|WP_041829870.1|3803204_3803447_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014443744.1|3791497_3791890_-|NUDIX-domain-containing-protein	unknown	unknown	gnl|CDD|240046
NC_017093.1|WP_041830989.1|3810996_3812496_-|M20/M25/M40-family-metallo-hydrolase	unknown	unknown	gnl|CDD|349873
NC_017093.1|WP_014443761.1|3812672_3814274_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|312032
NC_017093.1|WP_014443747.1|3794691_3795537_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NC_017093.1|WP_041829871.1|3804286_3804511_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_157434920.1|3804619_3805978_-|amino-acid-permease	unknown	unknown	gnl|CDD|129987

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_172666599.1|3803616_3804243_-|hypothetical-protein	gnl|CDD|236766	PRK10811, rne, ribonuclease E; Reviewed.	5.25882e-17
NC_017093.1|WP_014443755.1|3806060_3806483_+|universal-stress-protein	gnl|CDD|238182	cd00293, USP_Like, Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, athough Usp lacks ATP-binding activity.	2.91538e-17
NC_017093.1|WP_014443750.1|3797082_3798450_-|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|235917	PRK07046, PRK07046, aminotransferase; Validated.	0
NC_017093.1|WP_157435353.1|3808483_3809152_-|class-F-sortase	gnl|CDD|320678	cd05829, Sortase_F, Sortase domain found in the class F family of sortases. Class F sortases are mainly present in Actinobacteria, Chlorobacteria and Firmicutes. Their functions are largely unknown.	2.24685e-60
NC_017093.1|WP_014443758.1|3809256_3809829_-|hypothetical-protein	gnl|CDD|164795	PHA00370, III, attachment protein.	4.83962e-05
NC_017093.1|WP_014443748.1|3795617_3796130_+|SigE-family-RNA-polymerase-sigma-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	2.35794e-33
NC_017093.1|WP_014443745.1|3791975_3792602_-|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	4.28596e-40
NC_017093.1|WP_014443761.1|3812672_3814274_+|alpha/beta-hydrolase	gnl|CDD|312032	pfam08386, Abhydrolase_4, TAP-like protein. This is a family of putative bacterial peptidases and hydrolases that bear similarity to a tripeptidyl aminopeptidase isolated from Streptomyces lividans. A member of this family is thought to be involved in the C-terminal processing of propionicin F, a bacteriocidin characterized from Propionibacterium freudenreichii.	8.06983e-19
NC_017093.1|WP_157435352.1|3793727_3794618_-|phosphotransferase	gnl|CDD|270702	cd05153, HomoserineK_II, Type II Homoserine Kinase. This subfamily is composed of unusual homoserine kinases, from a subset of bacteria, which have a Protein Kinase fold. These proteins do not bear any similarity to the GHMP family homoserine kinases present in most bacteria and eukaryotes. Homoserine kinase catalyzes the transfer of the gamma-phosphoryl group from ATP to L-homoserine producing L-homoserine phosphate, an intermediate in the production of the amino acids threonine, methionine, and isoleucine. The Type II homoserine kinase subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	4.53172e-08
NC_017093.1|WP_014443743.1|3790278_3791271_+|IS481-family-transposase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	6.26328e-24
NC_017093.1|WP_014443756.1|3806473_3808303_-|hypothetical-protein	gnl|CDD|378931	pfam12708, Pectate_lyase_3, Pectate lyase superfamily protein. This family of proteins possesses a beta helical structure like Pectate lyase. This family is most closely related to glycosyl hydrolase family 28.	0.000368635
NC_017093.1|WP_157434920.1|3804619_3805978_-|amino-acid-permease	gnl|CDD|129987	TIGR00909, putative_amino_acid_transporter, amino acid transporter. [Transport and binding proteins, Amino acids, peptides and amines].	1.46278e-43
NC_017093.1|WP_014443744.1|3791497_3791890_-|NUDIX-domain-containing-protein	gnl|CDD|240046	cd04690, Nudix_Hydrolase_31, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	2.08071e-46
NC_017093.1|WP_041830989.1|3810996_3812496_-|M20/M25/M40-family-metallo-hydrolase	gnl|CDD|349873	cd03876, M28_SGAP_like, M28 Zn-peptidase Streptomyces griseus aminopeptidase and similar proteins. Peptidase family M28; Streptomyces griseus Aminopeptidase (SGAP, Leucine aminopeptidase (LAP), aminopeptidase S, Mername-AA022 peptidase) subfamily. SGAP is a di-zinc exopeptidase with high preference towards large hydrophobic amino-terminal residues, with Leu being the most efficiently cleaved. It can accommodate all except Pro and Glu residues in the P1' position. It is a monomeric (30 kDa), calcium-activated and calcium-stabilized enzyme; its activation by calcium correlates with substrate specificity and it has thermal stability only in the presence of calcium. Although SGAP contains a calcium binding site, it is not conserved in many members of this subfamily. SGAP is present in the extracellular fluid of S. griseus cultures.	1.91143e-145
NC_017093.1|WP_014443747.1|3794691_3795537_-|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	8.58339e-21

Protein sequences

>NC_017093.1|WP_014443750.1|3797082_3798450_-|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme
MSTDSGIDRARLRSLAERERTTFTERHPRSAGAYKEADHLFGRVPMTWMNKTAADFPIYLDRARGNRITDVDGNEFVDFALGDTGAMAGHSPAPVVEAVTRRISDLGGLSTMLPTEDAAVAGAELARRFGLPAWSFALTATDANRWAIRLLRAVTGRSKILVNSYCYHGSVDESLIVVGPDGNGMSREGNVGAPTDVTRTSRVAEFNDLEGLERELAHGDVAAVLMEPALTNIGIVLPDDGYLAGVRQLTRKYGTYLINDETHTFSAGPGGATAFWDLSPDVVTIGKAIGGGVPVGAYGLSRELADALSGRGDLDLVDMGGVGGTLAGNPVSMAATRATLEHVLTEDAFTHMIGTASAFAAGISKIIDGYGLPWSVSRLGARVEYRFANPAPRNGTESARSADGELEDFLHVYLANRGVLLTPFHNMALMCPETTMADVSRHHEIFDAALKELTA
>NC_017093.1|WP_014443749.1|3796135_3797086_+|hypothetical-protein
MNDEQLIKDAYEAIAGTAVSPERVRARLNARVTAHRQRRLLLAGAGVATVAVAVGVPVALRERRGEPALPVASPSVKTSPRTARRVSLLFTPQWLPDGLVERFRSVKFDVATGKPLGGNRSWYPTGSPYTVEVPKGSVSFSVGERIDDGSGEPVMVGSVRGTLRVTDSAWVEWQPTGKPSMIVSVYGTADDTEIALRVARSVAATEETMLVTMDVPEVPDAFAGSATFEVNPTGEGTGVQTLGYTSADLRSGFQLTTDAPQPNQTYLSVERDGMTVYLLGEEPGVVGSGLTLSETESRNIIYRVTFRPPDVSWAGF
>NC_017093.1|WP_014443748.1|3795617_3796130_+|SigE-family-RNA-polymerase-sigma-factor
MTFEDFLTARLPALLRYATVLACDTHLAEDIVQEVLARAQPRWARIAAADVPEAYVKRMIINELASWRRRRAARVVPLSHDALDAVSAPADEPQRAVGERDEMIRRIARLPLKQRIVIALRFYEGLSDQEIADLLGCRPATVRSHTSRALASMRANFPTASSAGTSRIGG
>NC_017093.1|WP_014443747.1|3794691_3795537_-|alpha/beta-hydrolase
MIETDVTVDGRTLHAYAHGDGDLVVMWHHGTPNIGTPPAPLFAAARRLGIRFIAYDRPGYGGSTPRPDRDIASAAGDAAAVADALGVGTFAVFGHSGGGPHALACAALLPGRVTAAVAGAGLAPFDAEGLDWFAGMGPGGVASLRSAAAGRAAKEAYAGNPAITDPDFTAADWAALEGAWGWFGSVVEPAIANGPAPLIDDDLAYVRPWGFDPATITVPVLLAHGEDDRMVPASHSVWLADRIKGAELRLTPGAGHISVLTAQDEAALEWIAAVGRTRENA
>NC_017093.1|WP_157435352.1|3793727_3794618_-|phosphotransferase
MEFLPLGAGSYSWSVVGRWFARVDDLGFDPAGRDEAFAELHRSLATAVSLRNDSGLDFVLAPLPDQTGAPLRRLSSRYALSLYPLVDGVAGPFAPHPPADRAEIVDLLARLHDAPPGLAPRITPALPGRSSLEVALGDLGSVWDAGPYAEQARALLAGRADDIHGWLAEFDRLVAELPADGVLTHGEPHPGNVLRTADGLLLIDWDTVAVAPPERDLWMLTGRFATLVGAQPDPGDEEVLARYTARTGRTVSEAGLALYPLWWTLADIAVFTDELRRGEDAPESLAYLGGYLRRRR
>NC_017093.1|WP_014443745.1|3791975_3792602_-|histidine-phosphatase-family-protein
MRTVYLVTHPEATHHVDGLVGGWFDSDLTPRGLAQAEQIAEALAGRLVVDAPVELFSSDLTRTRRTAEIVAKRLGIDVVLDADLREKSYGEAGGRPQVWLDGRFIPPPAAGERMRHDEGVPGAETKWQQAVRAYSALDRILRSNIENQIVVTHGGTATFLIAAWIGMPVDAAGFVSFQVSSGSITSLREDDYFHNRGVVHLNDTAHLT
>NC_017093.1|WP_014443744.1|3791497_3791890_-|NUDIX-domain-containing-protein
MIDKVAWIHLKDGAILSTRSIGKDVYYLPGGKREPGESDIDTLIREINEELDVIIVADSATHAGTFHAQAHGHPDGIMVRMTCYTAEYRGELRPNSEIEEIAWLTYANRHQVSAVDQIIFDQLHQKAKLE
>NC_017093.1|WP_014443743.1|3790278_3791271_+|IS481-family-transposase
MSHANAALTPRARLRLARLIVDHGWSPARAAERYDVSWRTAAKWAGRYRAEGEAGMHDRSSRPHRQPNRTPAPVVRKILHLRRKRRWGPVPIADEIGLAASTVHAVLLRQRANRLSHLDRATGEPIRRYEHAQPGDLLHVDVKKLGNVPDGGGWRYLGRQQGKKNRATTIGKPRNKHYNPMIGTAFVHTVIDDHSRVAYAEIHDDETAVTATAVLRRATTWFAERGVTTRRVLSDNGSAYKSHLWRDTCAELGITVKKTRPYRPQTNGKIERFHRTLADGWAFAKLYTSEKARRAALPAFLHDYNHHRPHTAIGKLAPITRLNNLAGHHI
>NC_017093.1|WP_014443741.1|3789095_3789491_-|hypothetical-protein
MAEDQRLLRIRPYYWGAIYLNDADCEEDFDIDFHDGGGPVLATASHVSVLVVNARTVDKADADVTVDVRVAPQRIDGLSHEVAFQLPSGRLYIGDADDSDEIAVQSGRWLLQFDVDDPAQARHVRLVMSPL
>NC_017093.1|WP_014443740.1|3788479_3788908_+|hypothetical-protein
MPAGDVAIHDVLADETARYVRRDGVVSGGLDRARDLGLWLSAESGALVVDRLPAGAAYPRHSGPARLFTLKPGETGRYRANFRFTVTTCACNPGWYYEDWLILIANCEMKADGFVSRKPDHHVDHRVHLYGGSLRPSRRHDK
>NC_017093.1|WP_041829870.1|3803204_3803447_-|hypothetical-protein
MNISAATTFTWNSSVAWSRLQSSRVKLAESLTSETADNGTLTTIRATIQNAASEISRVEAARATELARIRNNHQTIDVMV
>NC_017093.1|WP_172666599.1|3803616_3804243_-|hypothetical-protein
MVTPAVTSEVAPIEEPEKVEPVVTPERVAAPVAEPEPVAAAEPVVAPEPVAEPVAEPVAAPEPVAAPEPVAAPEPVAAPEPVAAPEPVAAPEPVAAPEPVAAAEPVAAAEPVVSSVVDDEPEAAPLTPAEIAAAVPADVPEPDDLTKIPGIGPKMAIALAAAGITTYAKLADSDADTLKQAVTSAGMRLAPTLKTWPDKARELIAVKS
>NC_017093.1|WP_041829871.1|3804286_3804511_+|hypothetical-protein
MDDTVDDTVDGAVDDDDDDDAGDTVDSGSGDGTTTGAAAGAADAAEAAGAGFAAPTRPLISQPAIAPIASPPTK
>NC_017093.1|WP_157434920.1|3804619_3805978_-|amino-acid-permease
MTDTHEEQPTLNRVIGPALLLLFVVGDILGTGVYALTGKVANEVGGAVWLPFLLAFVVALLTAFSYLELVTKYPRAAGAALYTHKAFGIHFLTFMVTFAVMCSGLTSASSASKAFAGNFAEAFDLSLGDGFALTAVALAFITLVALINFRGVGESVKANVVLTCVELTGLLIVIFIGAWALGGGEGDLSRLTEFNTPPGESITLSVTAGTALAFFAMVGFEDSVNMAEETRDPVRIFPKVMLTGLCITGLIYVLVAISSVALVTPAELGSGDTPLLKVVSAGAPGFPLSVFAFITMFAVANSALINMMMASRLLYGMANERVLPRVLGRVHRTRRTPWVGIVFTTVIAFGLIWFADLTALGGTTALLLLCVFTVVNVAVLVLRRDPVDHDHFKAPTVIPVLGALACAFLASPLSGRAGADYRVAGVLLLIGVVLWALTYAANRYLPDAVSRR
>NC_017093.1|WP_014443755.1|3806060_3806483_+|universal-stress-protein
MKIVLAANPEADQPWVTDAAADLVRQTGATVAVVAVDELESEHLAPMPRSVYTERAERARDAAVRRLAEAGIEATGTVLPGRPIDQIIRFGEEQSADLIVVGSSARPLVAQRLLGSVPLSLIQRAGRPVLVVTHPAKAQG
>NC_017093.1|WP_014443756.1|3806473_3808303_-|hypothetical-protein
MTRRRTTAGALALGLVLAVAGVSASPAAATPSSAAPNLGPNVTVFDPSMPVSEIQATLDATHAAQVNNEMGTQRYAYLFKPGTYGTAEQPLQIKVGYYTEVTGLGATPGDVVINGKVEVYNRCLTADNCLALVNFWRTVSNLTVNINAAGQDGCRSTANFWAVSQATSLRRVQFTGGGLSLMDYCTAGPQYASGGFIADSKLPATTNGSQQQWLTRNSQVASWSNAVWNQVFSGVEGAPDDATFPDPQYTTLEKTPVSREKPYLFVDAKGKYQVRVPAAQRNTSGVSWGGPGRTIPLSDFYVAKPGDSVTKINLALALGKHLLLTPGVYDIARSIEVWRPNTVVLGLGHATLTAVNGSTPLNVADVPGIVVAGVTIDAGTKESPVLLRVGSKHGHGLSNPNNPTTLQDVYFRVGGPHIGKTNIALEVNSDDVLIDHTWVWRGDHGVEGFTEGVNGDTDRWRTNTGRYGAVINGDDVTATGLFVEHFQKYNTVWNGERGTTVLYQNELPYDPPTQADWMNGKVKGYAGYKVGSKVKIHSLYGGGVYVFNQNNPTIETENGFEVPKTPGVKLHHIMTVNLSAGVINHVVNGVGEAADMTKVGQPVYVVDYP
>NC_017093.1|WP_157435353.1|3808483_3809152_-|class-F-sortase
MGLQSEAATPAPVAAEPARQEPSKNTTSIRPAPTTPGTRPATATGGAASDDSVPAPPPASATPRKAAPGSLARSEPVKLAISRIGLDTAVSRLGLRRDGTLEVPPLTADAPAGWYRHSPTPGEPGAAVIIGHVDSAREGPAVFFRLREVRLGDPITVRRKNGTVATFEVYRVATYPKHAFPTDEVYGATDRPELRLITCGGSFDRSRGSYRDNVVVYASLRK
>NC_017093.1|WP_014443758.1|3809256_3809829_-|hypothetical-protein
MSYSHAAPARRGRRDRAIALGVGLLLALLLLFIVLATCDNNGDNTGQPVPGASSSGPSGNPGPGASIDPGGGGPSNGSPDPGGVDPYPSGNAPSNGGNNGGGNNGGGDNGGGNNGGENGGGNNGGDDDEGNGSGGDDGSATTAPTPKGGVDAGGGSGAEDRRVPFLVMGVFLLLAASGTAAYAVGRRPRA
>NC_017093.1|WP_041830989.1|3810996_3812496_-|M20/M25/M40-family-metallo-hydrolase
MLQFPVAGLLIAGLLSAPAPVTAAAAPDISLTNVKAHLSQLQSIATANGGNRAHGRPGYLASVTYVKNLLDAAGFTTTQQSFTYNGATGYNLIADWPGGNTSNTLMIGGHLDSVTAGPGINDNGSGSAGILEVALQVARTGFKPDRHLRFAWWGAEELGLRGSTAYVNSLTSAQRSAITGYLNFDMIGSPNPGYFLYDGDNSDGTGAGPGPAGSAQIEATLAAYFSSIGVPTRGTDFDGRSDYGPFISAGIPAGGIFTGAEGTKTSAQVALWGGTASRFDPCYHASCDTISNINDTALDRNSDAIAYTVWALAGAGSPGGGTTVWSDDLETATSWTRGTADTATSGLFERGNPAATSSSGVATQLDAAAGGSYALVTGATAGSSAGANDVDGGVTSLLSPSITLPSSGTLTLSLSWYLAHLNNATSADYLRVRVVSGSTTTTVLTQSAAASNRAAAWATASANLSSYAGQTVRLQVEAADAGTASLVEAAVDSLKITQS
>NC_017093.1|WP_014443761.1|3812672_3814274_+|alpha/beta-hydrolase
MRRILAATIAASVGLLIGAGAIPATASAHGKGPGYTPPPIDWGKCASAGLNARGAECGFLVVPLDYAKPKGAKIKIAVSRIKHKSSAAQYQGVMLTNPGGPGGSGLTLSVLGEYVPDNAGSYFDWIGFDPRGVGSSVPALTCDVNYAGYNRPFYVPVTKQLEKTWLAKAKGYAKACDKAGGALLDHVKTTDTVADMESLRKALGQKQINYYGFSYGTYLGQVYATLHPDKVRKFVWDGVVNPERVWYDANLDQDIQFDKNMDVYFAWVAKYDSIYHLGKTAKVVKQKYYSTLYSLIKKPAAGKIGPDEWNDIFSSAAYYVFGWEATTEAFAAWVNDKDPSLLLEQYSEPGAAGSDNGYAMYLAVQCTDVKWPTNWSKWQRDNWKIYAKHPFMAWNNAWYNAPCITWGAKPGKPVEINGKKAPKMLLIAETNDAATPYSGALEVRKRFPKSVLVEGVGGTTHSGSLNGIACTDNIIAAYLATGDLPDRVRGNRSDAQCDPVPQPVPAGAPASTFSKRSAPAGLPADIRAEIGVR

Crispr_ID: NC_017093_11

• CRISPR_ID: NC_017093_11
• CRISPR_location: 3853033-3853126
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_11

Consensus_repeat	Method
GTGCCGCGTCGCTTCGCGGCTCGGCGGCGGC	CRISPRCasFinder

spacers of NC_017093_11

>11.1|3853064|32|NC_017093|CRISPRCasFinder
GCTCGGTGGCGGCGCGTGCCGCTTTGCCGGCA

CRISPR arrays and Neighbor proteins around NC_017093_11

CRISPR arrays

The CRISPR arrays of NC_017093_11

>merge|NC_017093|11|3853033-3853126|CRISPRCasFinder
GTGCCGCGTCGCTTCGCGGCTCGGCGGCGGCGCTCGGTGGCGGCGCGTGCCGCTTTGCCGGCAGTGCCGCGTCGCTTCGCCGCTCGGCGGCGGC

>NC_017093|11|11|3853033-3853126|CRISPRCasFinder
GTGCCGCGTCGCTTCGCGGCTCGGCGGCGGC	GCTCGGTGGCGGCGCGTGCCGCTTTGCCGGCA
GTGCCGCGTCGCTTCGCCGCTCGGCGGCGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_041830994.1|3860421_3861210_+|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|252734
NC_017093.1|WP_014443797.1|3852014_3852974_+|cyclase-family-protein	unknown	unknown	gnl|CDD|377240
NC_017093.1|WP_014443799.1|3853618_3854164_+|hemerythrin-domain-containing-protein	unknown	unknown	gnl|CDD|376622
NC_017093.1|WP_157434921.1|3861550_3862801_+|sporulation-protein	unknown	unknown	gnl|CDD|369195
NC_017093.1|WP_014443795.1|3849885_3850821_+|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl|CDD|376566
NC_017093.1|WP_014443793.1|3847776_3848910_+|FAD-dependent-monooxygenase	unknown	unknown	gnl|CDD|235874
NC_017093.1|WP_014443791.1|3845437_3846634_-|MFS-transporter	unknown	unknown	gnl|CDD|341026
NC_017093.1|WP_014443803.1|3857774_3859886_+|putative-glycosyl-hydrolase	unknown	unknown	gnl|CDD|130598
NC_017093.1|WP_172666600.1|3854581_3855364_-|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|252734
NC_017093.1|WP_014443802.1|3855441_3857757_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|237425
NC_017093.1|WP_172666680.1|3853191_3853605_-|DUF3817-domain-containing-protein	unknown	unknown	gnl|CDD|378962
NC_017093.1|WP_014443800.1|3854277_3854562_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014443794.1|3848922_3849867_+|VOC-family-protein	unknown	unknown	gnl|CDD|319904
NC_017093.1|WP_014443804.1|3859871_3860336_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014443792.1|3846733_3847663_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176151
NC_017093.1|WP_014443796.1|3850821_3852018_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|224423
NC_017093.1|WP_014443806.1|3861213_3861552_-|DUF861-domain-containing-protein	unknown	unknown	gnl|CDD|380356
NC_017093.1|WP_014443790.1|3844098_3845277_+|PrsW-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|379143
NC_017093.1|WP_014443789.1|3843433_3844102_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014443788.1|3842728_3843286_+|DUF2087-domain-containing-protein	unknown	unknown	gnl|CDD|378279

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_041830994.1|3860421_3861210_+|SAM-dependent-methyltransferase	gnl|CDD|252734	pfam04672, Methyltransf_19, S-adenosyl methyltransferase. This family contains a SAM (S-adenosyl methyltransferase) domain, with a central beta sheet with 3 alpha-helices on both sides. Crystal packing analysis of the structure Structure 3giw suggests that a monomer is the solution state oligomeric form. An unidentified ligand (UNL, cyan) was found at the putative active site surrounded by the residues His57, His170, Phe171, Tyr216 and Met22. The UNL is likely to be a phenylalanine or phenylalanine-like molecule. (details derived from TOPSAN).	7.48586e-103
NC_017093.1|WP_014443797.1|3852014_3852974_+|cyclase-family-protein	gnl|CDD|377240	pfam04199, Cyclase, Putative cyclase. Proteins in this family are thought to be cyclase enzymes. They are found in proteins involved in antibiotic synthesis. However they are also found in organisms that do not make antibiotics pointing to a wider role for these proteins. The proteins contain a conserved motif HXGTHXDXPXH that is likely to form part of the active site.	8.91525e-18
NC_017093.1|WP_014443799.1|3853618_3854164_+|hemerythrin-domain-containing-protein	gnl|CDD|376622	pfam01814, Hemerythrin, Hemerythrin HHE cation binding domain. Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor hemerythrin binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial NorA is a regulator of response to NO, which suggests yet another set-up for its metal ligands. In Staphylococcus aureus the iron-sulfur cluster repair protein ScdA has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger.	1.07875e-07
NC_017093.1|WP_157434921.1|3861550_3862801_+|sporulation-protein	gnl|CDD|369195	pfam07070, Spo0M, SpoOM protein. This family consists of several bacterial SpoOM proteins which are thought to control sporulation in Bacillus subtilis.Spo0M exerts certain negative effects on sporulation and its gene expression is controlled by sigmaH.	6.23543e-115
NC_017093.1|WP_014443795.1|3849885_3850821_+|fumarylacetoacetate-hydrolase-family-protein	gnl|CDD|376566	pfam01557, FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase family. This family consists of fumarylacetoacetate (FAA) hydrolase, or fumarylacetoacetate hydrolase (FAH) and it also includes HHDD isomerase/OPET decarboxylase from E. coli strain W. FAA is the last enzyme in the tyrosine catabolic pathway, it hydrolyzes fumarylacetoacetate into fumarate and acetoacetate which then join the citric acid cycle. Mutations in FAA cause type I tyrosinemia in humans this is an inherited disorder mainly affecting the liver leading to liver cirrhosis, hepatocellular carcinoma, renal tubular damages and neurologic crises amongst other symptoms. The enzymatic defect causes the toxic accumulation of phenylalanine/tyrosine catabolites. The E. coli W enzyme HHDD isomerase/OPET decarboxylase contains two copies of this domain and functions in fourth and fifth steps of the homoprotocatechuate pathway; here it decarboxylates OPET to HHDD and isomerises this to OHED. The final products of this pathway are pyruvic acid and succinic semialdehyde. This family also includes various hydratases and 4-oxalocrotonate decarboxylases which are involved in the bacterial meta-cleavage pathways for degradation of aromatic compounds. 2-hydroxypentadienoic acid hydratase encoded by mhpD in E. coli is involved in the phenylpropionic acid pathway of E. coli and catalyzes the conversion of 2-hydroxy pentadienoate to 4-hydroxy-2-keto-pentanoate and uses a Mn2+ co-factor. OHED hydratase encoded by hpcG in E. coli is involved in the homoprotocatechuic acid (HPC) catabolism. XylI in P. putida is a 4-Oxalocrotonate decarboxylase.	1.55881e-56
NC_017093.1|WP_014443793.1|3847776_3848910_+|FAD-dependent-monooxygenase	gnl|CDD|235874	PRK06847, PRK06847, hypothetical protein; Provisional.	1.12429e-153
NC_017093.1|WP_014443791.1|3845437_3846634_-|MFS-transporter	gnl|CDD|341026	cd17473, MFS_arabinose_efflux_permease_like, Putative arabinose efflux permease family transporters of the Major Facilitator Superfamily. This family includes a group of putative arabinose efflux permease family transporters, such as alpha proteobacterium quinolone resistance protein NorA (characterized Staphylococcus aureus Quinolone resistance protein NorA belongs to a different group), Desulfovibrio dechloracetivorans bacillibactin exporter, Vibrio aerogenes antiseptic resistance protein. The biological function of those transporters remain unclear. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.27514e-94
NC_017093.1|WP_014443803.1|3857774_3859886_+|putative-glycosyl-hydrolase	gnl|CDD|130598	TIGR01535, glucan_glucosid, glucan 1,4-alpha-glucosidase. Glucan 1,4-alpha-glucosidase catalyzes the hydrolysis of terminal 1,4-linked alpha-D-glucose residues from non-reducing ends of polysaccharides, releasing a beta-D-glucose monomer. Some forms of this enzyme can hydrolyze terminal 1,6- and 1,3-alpha-D-glucosidic bonds in polysaccharides as well. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NC_017093.1|WP_172666600.1|3854581_3855364_-|SAM-dependent-methyltransferase	gnl|CDD|252734	pfam04672, Methyltransf_19, S-adenosyl methyltransferase. This family contains a SAM (S-adenosyl methyltransferase) domain, with a central beta sheet with 3 alpha-helices on both sides. Crystal packing analysis of the structure Structure 3giw suggests that a monomer is the solution state oligomeric form. An unidentified ligand (UNL, cyan) was found at the putative active site surrounded by the residues His57, His170, Phe171, Tyr216 and Met22. The UNL is likely to be a phenylalanine or phenylalanine-like molecule. (details derived from TOPSAN).	1.16826e-83
NC_017093.1|WP_014443802.1|3855441_3857757_+|PAS-domain-S-box-protein	gnl|CDD|237425	PRK13557, PRK13557, histidine kinase; Provisional.	1.72043e-104
NC_017093.1|WP_172666680.1|3853191_3853605_-|DUF3817-domain-containing-protein	gnl|CDD|378962	pfam12823, DUF3817, Domain of unknown function (DUF3817). This domain is of unknown function. It is sometimes found adjacent to pfam07690 and pfam03176 which are both transporter domains.	3.15777e-27
NC_017093.1|WP_014443794.1|3848922_3849867_+|VOC-family-protein	gnl|CDD|319904	cd07239, BphC5-RK37_C_like, C-terminal, catalytic domain of BphC5 (2,3-dihydroxybiphenyl 1,2-dioxygenase). 2,3-dihydroxybiphenyl 1,2-dioxygenase (BphC) catalyzes the extradiol ring cleavage reaction of 2,3-dihydroxybiphenyl, the third step in the polychlorinated biphenyls (PCBs) degradation pathway (bph pathway). The enzyme contains a N-terminal and a C-terminal domain of similar structure fold, resulting from an ancient gene duplication. BphC belongs to the type I extradiol dioxygenase family, which requires a metal in the active site for its catalytic activity. Polychlorinated biphenyl degrading bacteria demonstrate multiplicity of BphCs. Bacterium Rhodococcus rhodochrous K37 has eight genes encoding BphC enzymes. This family includes the C-terminal domain of BphC5-RrK37. The crystal structure of the protein from Novosphingobium aromaticivorans has a Mn(II)in the active site, although most proteins of type I extradiol dioxygenases are activated by Fe(II).	9.93005e-72
NC_017093.1|WP_014443792.1|3846733_3847663_-|LysR-family-transcriptional-regulator	gnl|CDD|176151	cd08462, PBP2_NodD, The C-terminal substsrate binding domain of NodD family of LysR-type transcriptional regulators that regulates the expression of nodulation (nod) genes; contains the type 2 periplasmic binding fold. The nodulation (nod) genes in soil bacteria play important roles in the development of nodules. nod genes are involved in synthesis of Nod factors that are required for bacterial entry into root hairs. Thirteen nod genes have been identified and are classified into five transcription units: nodD, nodABCIJ, nodFEL, nodMNT, and nodO. NodD is negatively auto-regulates its own expression of nodD gene, while other nod genes are inducible and positively regulated by NodD in the presence of flavonoids released by plant roots. This substrate-binding domain has significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	8.53843e-41
NC_017093.1|WP_014443796.1|3850821_3852018_+|alpha/beta-fold-hydrolase	gnl|CDD|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	5.52301e-10
NC_017093.1|WP_014443806.1|3861213_3861552_-|DUF861-domain-containing-protein	gnl|CDD|380356	cd02227, cupin_TM1112-like, Thermotoga maritima TM1112 and related proteins, cupin domain. This family includes bacterial and plant proteins homologous to TM1112, a Thermotoga maritima protein of unknown function with a cupin beta barrel domain. TM1112 (also known as DUF861) is a subfamily of RmlC-like cupins with a conserved "jelly roll-like" beta-barrel fold; structures indicate that a monomer is the biologically-relevant form.	2.01623e-11
NC_017093.1|WP_014443790.1|3844098_3845277_+|PrsW-family-intramembrane-metalloprotease	gnl|CDD|379143	pfam13367, PrsW-protease, Protease prsW family. This is a family of putative peptidases, possibly belonging to the MEROPS M79 family. PrsW, appears to be a member of a widespread family of membrane proteins that includes at least one previously known protease. PrsW appears to be responsible for Site-1 cleavage of the RsiW anti-sigma factor, the cognate anti-sigma factor, and it senses antimicrobial peptides that damage the cell membrane and other agents that cause cell envelope stress, The three acidic residues, E75, E76 and E95 in Aflv_1074, appear to be crucial since their mutation to alanine renders the protein inactive. Based on predictions of the bioinformatics programme TMHMM it is likely that these residues are located on the extracytoplasmic face of PrsW placing them in a position to act as a sensor for cell envelope stress.	4.91699e-30
NC_017093.1|WP_014443788.1|3842728_3843286_+|DUF2087-domain-containing-protein	gnl|CDD|378279	pfam09860, DUF2087, Uncharacterized protein conserved in bacteria (DUF2087). This domain, found in various hypothetical prokaryotic proteins and transcriptional activators, has no known function. Structural modelling suggests this domain may bind nucleic acids.	3.79877e-15

Protein sequences

>NC_017093.1|WP_014443797.1|3852014_3852974_+|cyclase-family-protein
MIDPKDPEGAIAAAAKRCSNWGRWGADDVQGTMNFLTPEKRTQGARLVRRGVSFSLSQSFDANGPQKGWRRRTNPVHTMLDTGTDAVTGVQGFPHGLGGADDVIAMPLQCSTQWDGLGHIFDHGMTWNGRRADKVVTSLGDAVTGIETVAGVIAGRGVLLDVGRVLGEDGELPDGFAITEEHLRATIAAHGLEVGTGDIVLVRTGQLARVRRNGWGDYAGGPAPGLSFTTADWLHRTEIAAIATDTWGFEVRPNEFEEAFQPLHQVAIPHIGLFLGEMWDLDALAADCAQDGVYEFWLTAAPLPITGAVGSPVNPIAVK
>NC_017093.1|WP_014443796.1|3850821_3852018_+|alpha/beta-fold-hydrolase
MFEYFPGNYVWNLGVVATLNSGGLIDEVDRACRPIRDLAAQGSDVGTKEFMASWAAVAEDLATQAAADEKAGHLRTAGQKYQRATNYLAQAERMQSAKSPGRKAFYQRLLDLQQKAFDLIDPDTTRVAIPFEGTLLPAYFTKAGPAAAPTIILWNGLDSTKEHMYSSGFAHEMAARGINTLMVDCPGSGEALRFLGLTSRVETEDWATACVDYLLTRDDVQPEKIGLIGWSLGGYYAPRAAAFEKRLALCVAWGANHDWGAVQKRRLEREGENPVPHYWDHVLWVWGETDLDTFIKKAEAVNLDGVVEQITVPFLIAHGENDRQIPLQYAHRSYEQAVNSPQRELRIFTKEEGGAEHIGLDHFAHVQTFIADWVDDVFRGVSRSPHVSGSPHVSGSPR
>NC_017093.1|WP_014443795.1|3849885_3850821_+|fumarylacetoacetate-hydrolase-family-protein
MRIARFRHAGEIKTGQIHHHGVRVFAGSPEIGSIIAGGIAEAHRREVAQTVPLEEVQLLAPLQPSSIRDFVAFEEHVEGVRRSVDGSAGVPDAWYDAPTFYFTNPHAIYGPGDDVPFPAASVARDFELEVAAIAGPDRSIFGYTIFNDWSARDLQSREMQVRLGPAKGKDFASSLGPWIVTADELEPYRDADGFLDLWCTAAVNGVEVGRDLLSNMGWTFEAMIAYAGRDSRVEPGDVLGSGTVGNGGCLAELWGRNGTQDPPPLTDGDVVTLTVEGIGSLTNRITSGAENTGIPRVRRRDPAQARAERQS
>NC_017093.1|WP_014443794.1|3848922_3849867_+|VOC-family-protein
MTNDERLITHLRHVDLAVPDYDRQLEFYTDMWGLDAETSDEGIAFLAAAGSPEQYSVRLRKAAEKRLDLIAFGAANETDVNALAERLGRAGVTLVSEPGKLQTPGGGYGFRFFDIDGRTVEVSCDVAVRQHRRLEEGESVPVKLSHVVINSPNPEATVAFYDKHLNFALSDTLMHPRMGEMMWFLRTNRWHHSLAIARGPHVSLHHASFEMRGIDEYMRGTGRLLRGGVEKVWGPGRHMAGNNTFSYFLDPHGNTIEYTTELEELDEDSWHPHLYDFSDPTVSDQWGTANPMNEFVAKQSFNDVDRGVFVAPPV
>NC_017093.1|WP_014443793.1|3847776_3848910_+|FAD-dependent-monooxygenase
MPAVRNVLVVGGGAAGAAAAILLAEGGVAVDLVDVKPDVAAIGSGITLQGNALRVLRELGVWDKVKAEGYAFDTLGIRAPDPAGTLVAELTDIRTGGPDLPATLGMYRPALARILIDRATEAGVKIHFNRCPESLEQDGDTVRVTFAESGEEQRYDLVIGADGIRSWTRRRLGIDCEPQPVGMGIWRTFTKRPASVTRTDLIYGGPCYIAGYCPTGEDTLYAYLVEAVQDRFRLGPEESLATMRELSLAYHGPWDEIREQLTDPARVNYTAFESHVLDGPWHRGRVVLIGDAAHSCPPTLAQGAAQALEDASVLSQLLLTAGSVTDSLWSDFTGRRLHRAKTVVEASLQLAAWQLAHERGDVPGLMARVSQLVADPA
>NC_017093.1|WP_014443792.1|3846733_3847663_-|LysR-family-transcriptional-regulator
MAVDRMLANLDLNLLVTLDALLRERNVTRSAELLGLSQPAVSGALSRLRRHFGDPLLVRVGNRYDLTPLASRVAALTGPALAGVRRVFDSTTEVDPSELDREFTLVTSDYAAAILGPILARMLAERAPGARLRLQQTTPTAVDHAADTLRTADGLIIPYGFVTGLPHLDLYEDRWVCIVSADNPQVEESLSLVQLKHMPWVVLFDRPTAFAPAVRQLRMLGIEARVDVVVDGFMQMPFLVAGTGRVAVIQERLATLMAPIAGVRILECPFDVVTLNESFWWNPMNTNDPVHAWFRQLMIEAADLLWPSF
>NC_017093.1|WP_014443791.1|3845437_3846634_-|MFS-transporter
MSLTASTPIRQAGLTQLVLLLAGSCLSVLGAVLIAPVLPQMTDHFAGVPGADALVPIVLTVPALIIGLTAPFAGFIADRIDRKRVLVAAMVGYSIFGTAPLYLDSLPAIIGSRVLVGLCEAAIMTCCTTLIADYWSGPRRSRYLGMQTLLASVSATVFLGLGGALGSSGWRTPFWLYTVAVALAVPMAMLIWQPARPAVSAALPPIPWRQLRVPCLVTLAGGVVFYALIVELSFVLDEVGVTATATIGALSALMSLATAVAAGSFAKLSGQTPRTLLPIAFGLSAAGFLVIAATPSVPVITIGAVLTGAGTGLLLPTLLTWATNGLSFEERGRGTGLWTGTLFIGEFFSPILITGVGAAVGGLRPALGLLGVVAAILAVVMVMVVPRDAPRLNITQVD
>NC_017093.1|WP_014443790.1|3844098_3845277_+|PrsW-family-intramembrane-metalloprotease
MTTTSEPVPVAVPEPAIAARQAAIERTGWGNPVYLWQPRNAAFWLYLYLVGYGVWRLFGQVNYSVRLYAPALAASTIIFALYGVLFWWFTTRIDRYSRQPLKLIVAAFVWGGLAAPWAIALSGNSAFVDLLQKWFGQDFGFGPALSAPIFEELGKGAAVLLLLFIAPRVVRTAYDGFILGAFAGLGFEVFEDIFYALNAAPAEFGSNQIGASLHTVGLRLLSGFSSHILYSAVVGAGVVYLVGTVAQRRRAGLGIGLILTSMLLHGLWDSAGGYSNGVIASAVIILSLPGSFAVVIAVFHLTVRPERAAMRDVMLPEAEAGVITSEELDALAGGWKQRRAYRKAAHGKADRRARHHRLEAAHDLADQLAVSAGADSAGVRHARSEVARLRAA
>NC_017093.1|WP_014443789.1|3843433_3844102_+|hypothetical-protein
MTQTYVSDPADAQRWQENWVPVDRRLLGLDKRTLLPAAVVLLLFAVAVWILPAINNRVTVEDPVVAGDVIQVGSAVEFVPAVGANLLLGLRKGQPGPGGEYPSTAAVSYQGTVFEIITDTYDGTPAQLLEQIKKNDAGLRVPDGGGLHVTSEPVTITNAAGEHGVAAHYDGTQSVGLVAAFVFGGTGVEIEIVGPQQVQDNVTQQIAAMLRSVRSIAPGSGS
>NC_017093.1|WP_014443788.1|3842728_3843286_+|DUF2087-domain-containing-protein
MSIAAARAADLLMQLSRPARLRAFAELVRAGSDGATIAELSIYLDQPKPEVAELLGRLVGAGLAGGTGNGVFRVRADVLREAAQLLDREQPINALLIDFPQLKSYFSHGRLTGLPPTLSDRYQQIAELFARFLAVEGVLTEDEVNARIAPVADDVAAVRRMLVETGWLERDRAGRSYGSARLPTS
>NC_017093.1|WP_172666680.1|3853191_3853605_-|DUF3817-domain-containing-protein
MLTNRSEGNYPHCQQTLIFDRVRSAPPKSRGKHVQAFRVFRITAVAEAFSWTGLLVGMYLKHVTHTTEAGVWFFGRLHGALFVAYLAATLWVARSERWSLWRTLFGLAASIPPLTTLIFERWVAKRRPAAEPAAATA
>NC_017093.1|WP_014443799.1|3853618_3854164_+|hemerythrin-domain-containing-protein
MPDIVEVIKEQHRQVDELLEEATHDGVDKASLLHEVHRMLLPHSEAEEDFVYPAIRDKAAEAGEEVVDGAVEHHQIEEMLQNLLRGNPDAPGYDGTLAAIIGELRHHVQEEEEELLPILQDSLTTEEREQMGRRFLEATTAKLPEEEHHTKSELYDLAREQEIPGRSTMTKEELAEALGDG
>NC_017093.1|WP_014443800.1|3854277_3854562_+|hypothetical-protein
MAEISAERMRPCRRCGHPTRVDRMIQGYGRNCATLLGLVGGTVDTGHSGPDLLDLLGRSPTPAEPFEPEPEPEDECDGGDRPADAPVASGRSTR
>NC_017093.1|WP_172666600.1|3854581_3855364_-|SAM-dependent-methyltransferase
MSTTAEPPIDPNRPSSARIYDVFLGGTHNFASDRAVAARTAELLPQTPMIARHNRAFLRRAVRFATARGVDQFLDIGSGIPTEQNVHQVAPEARVVYVDIDPTAVIYARHLLGDDPRLVVVHGDVREPAPVLDDPAVRGLLDLSRPLGILMVAVLHFVPDSPVLTEALRIYREAAVPGSVLAISHVSASAQPTELDRVADLYNRTGASLVPRDREQMERLFEGWTLVDPGVVFGPSWRPDPGEEVDDPAQFLTLAGVAVR
>NC_017093.1|WP_014443802.1|3855441_3857757_+|PAS-domain-S-box-protein
MEFREIPGLLLDTAPDAIVVSRSDGTITLANRRAHDMFGYPAGELVGRAVDDLVPEDARSRHPARRSAYLAGDHPPLRRLPLRGLRRDGSVFPVEISLSAVTPAGDETYVTSVLRDDTAQREAARTRALLASVVQSSHDAIVTTDLDGVVLSWNPGAEMLYGHPAADMIGRTVDVIIPDERRSDEEQIRMLVRLGGRVDRYRSTRLTAKNEQISVSTLISPLLDERGNMIGTTTITRDISDRERAEARVQAILDAAPDAMLGVAESGEVVLVNAEAERLFDHPRYDLLHMPLPLLLPDGLPPVSAVLRTGSDSTPLDTERAGDTPAEYGDQRWATRRALRRGGAELPVDLACSSLHTDSGVVIVVVVRDITERLAAEQERRRLREEAERQRLEARMQQAQRLESLGQLAGGIAHDFNNLLAVILNYASFIVEDATGTPSAADAEQIARAARRGSDLTHQLLAFARREVIRPRPLNLNVVVTEVHQMLERSLGEHIALTVRTTAGLPSVMADPGQLEQVLVNLAVNARDAMPTGGRLTIDTAPVQVDAEYAARLDLRIGSYVRLRVSDTGTGMPREVIDKAFEPFFTTKPSGQGTGLGLATVYGIITQAGGTVRIYSESGIGTTFTILLPATDMEAREASPEETAEELSGHGAVVLVVEDEAALREVTSRILRRGGYTVLVAGSGEEALRLAAENTVDVLLTDVIMPGMLGRDLASAVHRSSPGTKVLFMSGYAQPVLTTHGTLSADVHLLEKPFTSAELMRALHDELQARP
>NC_017093.1|WP_014443803.1|3857774_3859886_+|putative-glycosyl-hydrolase
MAYRKVATALLAVIIGLDPVGARPTQAAPSEPAGPAPGAPGTDQQYLPADKAGLLTATGTRSKVWVTLQRGGGIGEIFYPDLGTPSARALQFQVTGPSGVARMPQPSTELTSDRSLSYRQTWEDPAGRWRLVADYTVDPDAAVLLVRVRLSGHGHRLYTIYDPALNNSRGGDSGRTEGNALIATDGPVTSALVAKPGFTATSNGFAGTSDGWTDLADGRMDWRYASASAGNLVQTAAVAPESTLALGFGSSALRDASAVLHRGFAGVDRSYARGWGSYLRTLSRPPSVADRRLWRVSAMILAASEDKTHRGAYIAAPAAPWAFGRDDPSGPYHLVWARDLYQIATGLLAAGDRAGAERAVDYLFGVQQKPDGSFPQNSRLDGTPVWEGLQLDEVALPIVLAYQLNRASAWPGVKRAADFLTGYDQAPNSPQDRWENQSGYSPATIAASIAGLVCAASMARAHGDTASAARYEATADAWQKNVKAWTVTSTGPYSDKPYFLRLTKDGQPDRGTTYDIGDSGPSGVDQRRVVDPGFLELVRLGVLPAGDPVFADSLAVVDEQLGVPVRGGLYWYRASFDGYGEKADGSQWDYPLPADSRITRGRLWPLLNGERGEYAIAAGSLREARQQLRLMARAAGPSLVLPEQVWDRQPPYRPAGTPTTSATPLTWTHAQYLRLAGNVAAGRIVEQPRVVAQRYQRLSSGQR
>NC_017093.1|WP_014443804.1|3859871_3860336_-|hypothetical-protein
MATQAPPYRPVLPGFPPDDTAHGNGGSAIAVTMRYAPLAFLLGMFVPVLEIDGQPVPASWGRVVTSVALGQHHVHVHVPYLMPSRIGAAETTVLAVSGRTVELEYRAPLLSFLHGNLGVPPQRYPGLVAAVALLVLAVTLLGCGCLGIILSALS
>NC_017093.1|WP_041830994.1|3860421_3861210_+|SAM-dependent-methyltransferase
MNPSVDDQTVSPARRWNYWLGGKDHFQVDRESGDRIAAAYPAVRTAAQQGRAFHNRAIRYLAGEAGIRQFLDIGTGLPAPDNTHEVAQSIDPASRVVYVDNDPMVLAHARALMTGGTTTFVHGDLNDPGAILAADELRDTLDLSRPVAILLIAVLHFIPDDDKARAVVRELVDAAAPGSYLVATNSTKDFVPPHVAAVYDQMLAAGHVDAWPRDKDTFGSFFDGLELVDPGAVAISEWRPDSEDRPAAAEVSMYGAIGLKSR
>NC_017093.1|WP_014443806.1|3861213_3861552_-|DUF861-domain-containing-protein
MERVAVFPLAEVLVPHQPADPAVIVSGTPTTGSVSVTGITGVEVGVWEMSSGSVRDVEAEEVFLLLAGHGVIELADGARFAIKAGDLVRLAAGTKTVWHVDEPLRKVYITGA
>NC_017093.1|WP_157434921.1|3861550_3862801_+|sporulation-protein
MTLHPSRTVAVQVFQGFFSLHCYFSDQAGFPSCPVVGALSKRELNVVFKKLLGALGVGGPSVDTVLSNPSTYPGAPLTGQVNVVGGTQDADIEHITLGLVTRMEVEGGGGDYSAVADFHRLTVSGPMRLAAGQQLSIPFQIDMPWETPITTVYGQTLRGMVMGVRTEVAIARAVDKGDLDAVHVHPLPIQQKILDAFSQLGFRFKSADLEHGQIYGVHQTLPFYQEIEFYPPQQYAHGINEVELTFVTSPHSVEVVLEFDKRGGLFTQGHDTYGRYTVQHQDADTTDWRAVVDGWVRQALDKRKSMPGFGAGGGFGQPGHGQPGYGQPGYGQPGYGQPAYGAPGYPPPGYGQPGYGHGPGHHGHYRQGPGHHGHYRRGHHGGGMGGMAMGVAGGLAAGYVAGEVFDEIGDAFEGEE

Crispr_ID: NC_017093_12

• CRISPR_ID: NC_017093_12
• CRISPR_location: 3932360-3932459
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_12

Consensus_repeat	Method
GGGGCAGGCTGGACCGGCGTGATCACCGTGTTCGGCT	CRISPRCasFinder

spacers of NC_017093_12

>12.1|3932397|26|NC_017093|CRISPRCasFinder
ACGGCCCGGATTCGCGAGCCGTCGCT

CRISPR arrays and Neighbor proteins around NC_017093_12

CRISPR arrays

The CRISPR arrays of NC_017093_12

>merge|NC_017093|12|3932360-3932459|CRISPRCasFinder
GGGGCAGGCTGGACCGGCGTGATCACCGTGTTCGGCTACGGCCCGGATTCGCGAGCCGTCGCTGGGGCAGGCTGGACCGGTGTGATCACCGTGTTCGGCT

>NC_017093|12|12|3932360-3932459|CRISPRCasFinder
GGGGCAGGCTGGACCGGCGTGATCACCGTGTTCGGCT	ACGGCCCGGATTCGCGAGCCGTCGCT
GGGGCAGGCTGGACCGGTGTGATCACCGTGTTCGGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_041829881.1|3929027_3930056_-|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|380525
NC_017093.1|WP_157435355.1|3922753_3923896_+|response-regulator	unknown	unknown	gnl|CDD|381113
NC_017093.1|WP_014443868.1|3932530_3933322_-|inositol-monophosphatase-family-protein	unknown	unknown	gnl|CDD|238815
NC_017093.1|WP_041831001.1|3926522_3927479_-|sugar-ABC-transporter	unknown	unknown	gnl|CDD|119321
NC_017093.1|WP_014443870.1|3936025_3936616_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_017093.1|WP_014443877.1|3944933_3945797_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224097
NC_017093.1|WP_014443869.1|3934110_3935754_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_017093.1|WP_157434925.1|3930443_3931439_-|DUF3618-domain-containing-protein	unknown	unknown	gnl|CDD|378834
NC_017093.1|WP_014443862.1|3925467_3926526_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|119321
NC_017093.1|WP_014443864.1|3927511_3929023_-|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224053
NC_017093.1|WP_157434924.1|3930200_3930362_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014443874.1|3941017_3942469_+|gamma-aminobutyraldehyde-dehydrogenase	unknown	unknown	gnl|CDD|143411
NC_017093.1|WP_157435356.1|3923865_3924285_-|Hpt-domain-containing-protein	unknown	unknown	gnl|CDD|366732
NC_017093.1|WP_014443875.1|3942516_3943674_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226361
NC_017093.1|WP_014443867.1|3931435_3931855_-|phage-holin-family-protein	unknown	unknown	gnl|CDD|377816
NC_017093.1|WP_041829883.1|3938040_3939531_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|143404
NC_017093.1|WP_014443861.1|3924319_3925471_-|L-rhamnose-isomerase	unknown	unknown	gnl|CDD|274239
NC_017093.1|WP_157435357.1|3936649_3937981_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|185378
NC_017093.1|WP_014443873.1|3939541_3940879_+|aspartate-aminotransferase-family-protein	unknown	unknown	gnl|CDD|235687
NC_017093.1|WP_014443876.1|3943718_3944930_+|spermidine/putrescine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270308

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_041829881.1|3929027_3930056_-|substrate-binding-domain-containing-protein	gnl|CDD|380525	cd06302, PBP1_LsrB_Quorum_Sensing-like, periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs. Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs from other bacteria. The members of this group are homologous to a family of periplasmic pentose/hexose sugar-binding proteins that function as the primary receptors for chemotaxis and transporters of many sugar based solutes in bacteria and archaea and that are a member of the type 1 periplasmic binding protein superfamily. LsrB, which is part of the ABC transporter complex LsrABCD, binds a chemically distinct form of the AI-2 signal that lacks boron, in contrast to the Vibrio harveyi AI-2 signaling molecule that has an unusual furanosyl borate diester. Hence, many bacteria coordinate their gene expression according to the local density of their population by producing species specific AI-2. This process of quorum sensing allows LsrB to function as a periplasmic AI-2 binding protein in interspecies signaling.	6.37097e-120
NC_017093.1|WP_157435355.1|3922753_3923896_+|response-regulator	gnl|CDD|381113	cd17569, REC_HupR-like, phosphoacceptor receiver (REC) domain of hydrogen uptake protein regulator (HupR) and similar domains. This family is composed of mostly uncharacterized response regulators with similarity to the REC domains of response regulator components of two-component systems that regulates hydrogenase activity, including HupR and HoxA. HupR is part of the HupT/HupR system that controls the synthesis of the membrane-bound [NiFe]hydrogenase, HupSL, of the photosynthetic bacterium Rhodobacter capsulatus. It contains an N-terminal REC domain, a central sigma-54 interaction domain that lacks ATPase activity, and a C-terminal DNA-binding domain. Members of this family contain a REC domain and various output domains including the cyclase homology domain (CHD) and the c-di-GMP phosphodiesterase domains, HD-GYP and EAL. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.68216e-45
NC_017093.1|WP_014443868.1|3932530_3933322_-|inositol-monophosphatase-family-protein	gnl|CDD|238815	cd01637, IMPase_like, Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1,6-bisphosphate, inositol poly- and monophosphates, PAP and PAPS, sedoheptulose-1,7-bisphosphate and probably others.	2.26613e-44
NC_017093.1|WP_041831001.1|3926522_3927479_-|sugar-ABC-transporter	gnl|CDD|119321	cd06579, TM_PBP1_transp_AraH_like, Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.	3.21808e-63
NC_017093.1|WP_014443870.1|3936025_3936616_-|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	1.60397e-22
NC_017093.1|WP_014443877.1|3944933_3945797_+|ABC-transporter-permease	gnl|CDD|224097	COG1176, PotB, ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism].	5.9662e-74
NC_017093.1|WP_014443869.1|3934110_3935754_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.1791e-103
NC_017093.1|WP_157434925.1|3930443_3931439_-|DUF3618-domain-containing-protein	gnl|CDD|378834	pfam12277, DUF3618, Protein of unknown function (DUF3618). This domain family is found in bacteria, and is approximately 50 amino acids in length.	2.3028e-06
NC_017093.1|WP_014443862.1|3925467_3926526_-|ABC-transporter-permease	gnl|CDD|119321	cd06579, TM_PBP1_transp_AraH_like, Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.	5.16103e-59
NC_017093.1|WP_014443864.1|3927511_3929023_-|sugar-ABC-transporter-ATP-binding-protein	gnl|CDD|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NC_017093.1|WP_014443874.1|3941017_3942469_+|gamma-aminobutyraldehyde-dehydrogenase	gnl|CDD|143411	cd07092, ALDH_ABALDH-YdcW, Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like. NAD+-dependent, tetrameric, gamma-aminobutyraldehyde dehydrogenase (ABALDH), YdcW of Escherichia coli K12, catalyzes the oxidation of gamma-aminobutyraldehyde to gamma-aminobutyric acid. ABALDH can also oxidize n-alkyl medium-chain aldehydes, but with a lower catalytic efficiency.	0
NC_017093.1|WP_157435356.1|3923865_3924285_-|Hpt-domain-containing-protein	gnl|CDD|366732	pfam01627, Hpt, Hpt domain. The histidine-containing phosphotransfer (HPt) domain is a novel protein module with an active histidine residue that mediates phosphotransfer reactions in the two-component signaling systems. A multistep phosphorelay involving the HPt domain has been suggested for these signaling pathways. The crystal structure of the HPt domain of the anaerobic sensor kinase ArcB has been determined. The domain consists of six alpha helices containing a four-helix bundle-folding. The pattern of sequence similarity of the HPt domains of ArcB and components in other signaling systems can be interpreted in light of the three-dimensional structure and supports the conclusion that the HPt domains have a common structural motif both in prokaryotes and eukaryotes. In S. cerevisiae ypd1p this domain has been shown to contain a binding surface for Ssk1p (response regulator receiver domain containing protein pfam00072).	1.20956e-08
NC_017093.1|WP_014443875.1|3942516_3943674_+|ABC-transporter-ATP-binding-protein	gnl|CDD|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	3.32818e-160
NC_017093.1|WP_014443867.1|3931435_3931855_-|phage-holin-family-protein	gnl|CDD|377816	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III. Phage_holin_3_6 is a family of small hydrophobic proteins with two or three transmembrane domains of the Hol-X family. Holin proteins are produced by double-stranded DNA bacteriophages that use an endolysin-holin strategy to achieve lysis of their hosts. The endolysins are peptidoglycan-degrading enzymes that are usually accumulated in the cytosol until access to the cell wall substrate is provided by the holin membrane lesion.	1.79133e-28
NC_017093.1|WP_041829883.1|3938040_3939531_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	gnl|CDD|143404	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2. Methylmalonate semialdehyde dehydrogenase (MMSDH, EC=1.2.1.27) [acylating] from Bacillus subtilis is involved in valine metabolism and catalyses the NAD+- and CoA-dependent oxidation of methylmalonate semialdehyde into propionyl-CoA. Mitochondrial human MMSDH ALDH6A1 and Arabidopsis MMSDH ALDH6B2 are also present in this CD.	0
NC_017093.1|WP_014443861.1|3924319_3925471_-|L-rhamnose-isomerase	gnl|CDD|274239	TIGR02635, putative_xylose_isomerase, L-rhamnose isomerase, Streptomyces subtype. This clade of sequences is closely related to the L-rhamnose isomerases found in Pseudomonas stutzeri and in a number of the Rhizobiales (TIGR02629). The genes of the family represented here are found in similar genomic contexts which contain genes apparently involved in rhamnose catabolism such as rhamnulose-1-phosphate aldolase (TIGR02632), sugar kinases, and sugar transporters. [Energy metabolism, Sugars].	0
NC_017093.1|WP_157435357.1|3936649_3937981_-|GntR-family-transcriptional-regulator	gnl|CDD|185378	PRK15481, PRK15481, transcriptional regulatory protein PtsJ; Provisional.	1.29853e-74
NC_017093.1|WP_014443873.1|3939541_3940879_+|aspartate-aminotransferase-family-protein	gnl|CDD|235687	PRK06062, PRK06062, hypothetical protein; Provisional.	0
NC_017093.1|WP_014443876.1|3943718_3944930_+|spermidine/putrescine-ABC-transporter-substrate-binding-protein	gnl|CDD|270308	cd13590, PBP2_PotD_PotF_like, The periplasmic-binding component of ABC transporters involved in uptake of polyamines; possess the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain that functions as the primary high-affinity receptors of ABC-type polyamine transport systems. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.50232e-91

Protein sequences

>NC_017093.1|WP_014443867.1|3931435_3931855_-|phage-holin-family-protein
MTHTDARTEQASTAELVSRLSEQVTTLVRDELALARIEMVEKGKKAGKGAGLLGGAGVIAAYGLGALFVTIGAALALVMPVWAAALIVTVVLFAGAGVAALIGKKEVQQAVPPSPEQAMESGRRDVDALMTAARNGRHS
>NC_017093.1|WP_157434925.1|3930443_3931439_-|DUF3618-domain-containing-protein
MSDDKPGSRQHSPGTPTPTHGASSNPPAASGKPSPRPAGSGSVNATARPAQGRNAKQHSSKPGGPKPAPPPNQNRTGPGPAKPARGDAPPGTGRKPANPTSLGTATAGAPGKPETDTTAAAKPEPVTEAAKGGATASAATTGKPAEPAKIGTTGSTPLPKTTADTKAGSGADGKTGNGADSKTGNGADSKTGNGADSKTGSGADGKAGSDGSGADGKRDTARDTARDSAGDEGDPSRRTRELKDEIARTRTEMGETAAALAAKADVPGRVRQGAAETSTHVAEGVAEAAEQARAAIGSVPRRVGAEPQRYALLGAAVAAAAAGVVLIRKAR
>NC_017093.1|WP_157434924.1|3930200_3930362_+|hypothetical-protein
MRRFKEWVSGTGFSALLPRWLPALLPRWLPAPHPGLAPGAVFRVGSRRWAGQH
>NC_017093.1|WP_041829881.1|3929027_3930056_-|substrate-binding-domain-containing-protein
MRPRFTAAVALTATAALALTGCTKKNDDTAAGGDASGDKTYKVAFVPKLQGVPYFEAMNAGGKEAAAALGNVEWLYQGPTQADAAAQADIVRSYIQQKVDALIVAPNDPDSMAPLLQQAKDAGIHVATADTDAPSSVREVFVNQATAEGIGQGLTDSLLTAMGGKGKYAIVSCGQTAENLNSWIEVQKAYTKEKYPEAEIVDIVYAGEDQAKATQMATDLMNAHPDLTGLVGECTSSAPGVAQAVKDAGKIGKVFTVGLGTPQSMKPYLTDKSSTAAILWDVENLGYLTAWAGAQLAQGKPFAATNNVSSDLSAVAYTEADKMLLLGPALAITDKNVDQFNY
>NC_017093.1|WP_014443864.1|3927511_3929023_-|sugar-ABC-transporter-ATP-binding-protein
MTQENETPRLRLTAVSKRFGAVRAIQHADLTVRAGQVHALVGENGAGKSTMIKIVAGAEQSDTGEIEWDGRPVRIGSTTDAIALGIATVYQEPQLFPELTVAENIFLGKEQRSGFLKKVDWAAQNAKVVELLELLGLPAKYATATVGDLSIAEQQQVSIAKALSGDAKVLILDEPSAILTDAEIETLFTVVRRLTASGVSVIYISHRLDELFRIADEVTVMRDGRTIGTYPIGELSVRQIAHLMVGEELSDDRPHREVPEGPAVLELQGLTRTGKFRDVDVQVRAGEIVALYGLVGSGVSEIAASCYGIERATSGTIKINGTAQSPRSPEHAQKLGIALLPANRKVEGMFGFQSIAFNISAGHLKLLSKLGVFVDRGREKVVALDMIKRLAVRTPHERQPISAMSGGNAQKVVLARQLVERPKVLILAEPTQGVDVGAKEEIHRLITELAEEGTAVLVVTSDLPEALRIADRIQVVRGGTTTEEFGPDAKQVDLLAAAAGGSE
>NC_017093.1|WP_041831001.1|3926522_3927479_-|sugar-ABC-transporter
MTNPITGQEIVLVGVIAVLWAALAVSTPAFLTAGSIQPLLVATAPIALVGVGMTIVIITGGIDVSVGGAIMVCSVITAKTLVSSDVSLGVAVLISLLSGGVLGLINGVLIAYGRVHAIIITFGTANIFMFLGLQIFGSGTVNGIPATLGFFGRGEDGRTLGVPHAFLVTILITAACWWYLRHTAGGRHFYAIGGDAQAARLAGVRVQRRVLLAYVITGLLVGLASCFVIAQGTSTLDQSVGSGKELAVIAAVVIGGTSIMGGRGSVLGTLLGALLVQTVSSGVTQLGWRSQLSDLFVGIFIIVAVGADLLRARARRSR
>NC_017093.1|WP_014443862.1|3925467_3926526_-|ABC-transporter-permease
MTAATVEKREKTDITRLFLTQRIPLLAVLIVIVVVTFFINDAGGYLTAPYDFDYMSASLINAVPLAMLGLAEMLVILSGRGGIDLSVGAIVSLAGMVFGFAYGEWGWPLWMAIIATAGFGALCGAINGFLVSYIGFPALIATLATFYAFKSIAIVINNQQPISTAPIQDLFSLSKSVELPIIGQYIPDVPLGIFTFLLPTVVAVWLLLARTAYGRRLYGIGTNDVAARWAGLPVRDTRFKAYVYAGLISGLVAVVTVAQFASARPDAGVSGNGMALPAITIAVLGGVAITGGIGRVAGVVLATLLIVWLNAGILLAFVGNEGSQYQLLALGAVLVFAALLNGLTNRKYGGAQ
>NC_017093.1|WP_014443861.1|3924319_3925471_-|L-rhamnose-isomerase
MNLDGLNDFSIEVPSWAYGNSGTRFKVFTTKGVPRNPYEKISDAAEVNRLTGLAPRVSLHIPWDLVDDWSDLRRHAEENGVTIGAVNSNLFQEDDYRLGSLCNPDPAVRRKAVDHHLQCLDVMRQTGSTDIKVWLPDGLNYPGQDSLRGRQERLAESLRAIYDALDPDQRMLLEYKLFEPAFYSMDIPDWGTSLLHCLALGEQATVVLDTGHHAPSTNIEFIVMQLLRQNRLGAFDFNSRFYADDDLIVGSADPFQLFRIMSEIVAAGAHRPESKVNFMLDQCHNIEEKIPGQIRSVLNVEQALAKALLIDQEALAVAQRDGDVLGANAILMDAYETDVRTALADRREERGLPRDPVAAFLASGYAQKAATDRAGGTQASWGA
>NC_017093.1|WP_157435356.1|3923865_3924285_-|Hpt-domain-containing-protein
MVFMGSIAPPDHDARVTAVRARLDDVTGGEPGPDELALLVRLLRAFAVRAPEAAEQVITLLSSGSEDLRDRAHALKGSAANIGAAGLSALCASIEQDARAGVRPDPVATAEMLRAETAAVLRAVTEVADAYEERRTRYR
>NC_017093.1|WP_157435355.1|3922753_3923896_+|response-regulator
MLLVDDEEAVLQTLALQLGPDHTLLTASNGADALRMLAENGPVAAVVSDMRMPNMDGIELLRRVQVEYPDTIRVLHTGHGDIDTAIAAINSGGVYRYLPKPAGTGELRSIVGDAVARHGQAMAERELLDKTLRTSVQALFGCLELASPVAFARAGRIRALVAELCHELQLDGLWEIEVAAMASQLGAVTVPPAVLKKLDRGVPLGPDEQAMVTAMPRAAVRLLRDIPMLHDVVAMAEGLAGEPEPESGRSALVEAGISVIRTAIEYEIVESRSANSATAIGVLEERGDGAPHVLAALRRIKGVRAHQEVVKSLRIMELEVGMRLAEDVVALNGLVLIGRGTVATEVMLDRLANFARVVDIVEPVLAAVPDFHRYLVRRSS
>NC_017093.1|WP_014443868.1|3932530_3933322_-|inositol-monophosphatase-family-protein
MPIDDHEVAIAAAEAGAAVVRARYGNALGRVDKGGGDFATEADIAAEQAILAVLREHRPDDAITGEESGSTGPAAARRRWLVDPLCGILNYAARNPLVAVNVALHDAGSARAAASADPFTGETFWTGGQFSRVRRDRHDHPLTPSPDSALVDVNLDPPFDSHPARLLSAPGFTERFRPRVLSTTLALVWVATGQRASYVTYGSVRESVHFAAAIAICEAAGCVVTGVQGQPLHTGPGGLLVAADAATHAELRDLVIASWSPAA
>NC_017093.1|WP_014443869.1|3934110_3935754_+|serine/threonine-protein-kinase
MPDAPTILAGRYRLGELLGRGGMGAVRLARDETLERDVAIKEIDQPPGEEGGAAARRTLREARAAARLSHPAVVQVYDVLQLDGRTWIVMEYVPSRSLKQVISEDGPVDPGRAARIGLELLGALRAAHRNGVEHRDVKPANVLLADDGRVMLTDFGIAAMDDDSVISRSDVVVGSPHFMAPERARLGVSGPEADLWSLGATLYAAVEGHSPYERSSTMATLTALATEEPEPPAHAGPLRPVLDGLLRKDPKQRIGIEEAERLIRASVEETGALPVPTEEEARPATASRIPAQRTAPLPGEVPDDVRRRNPRLLAALAAVVLVALAGLAFVLTRPDAENTAQRDPQPSTTTTTTTGAQGANPPAATGGATTTAVPSASSAPASASPSPSAASSASSSAAGGRPQLPAGWKNYTDATGFSVYVPEGWKKSERGTMVYFRGDGRVLGIDQTDEPKSNPVKDWENQSQYRVSRGDFPNYDEIKIDPVKYFRKAADWEFTFTRSGTRVHVNNRGAVVADDKAYGFYWETKDSEWNAARKDLQLVFDSFVPAK
>NC_017093.1|WP_014443870.1|3936025_3936616_-|Uma2-family-endonuclease
MSACDTLPMSEETLLDHPGPWTEEDYFALGETNSRIELVDGSLWVTPSANGPHQDISGQLREALRPTARPAGLRVRQDLDVRLAPGRILRPDLIVTRGPRVITVAEASDVLLVSEITSPGNAATDRLLKKELYAAAKIEWYLLIEPDMADYESLTLRLFRLDGDKYLEDAVATSGTSLILTEPFPATIDVDNLLDL
>NC_017093.1|WP_157435357.1|3936649_3937981_-|GntR-family-transcriptional-regulator
MLNAVMERLLDPSARGLAEAVSRAVGDGALAPGVKLPPVRRVAAELHLSPSTVNAAWQLLRRSGTIRTDGRRGTVVATAGTGGPGRYRAALRGTSGFGLDLSTGVPDPALLPPIPALHGLSPAPTSYLDEPVLPELGTLLRERWPYPIDRLAVFDGAMDAVDQVASALLRLGDLAVVENPCFPPLLDLLEVLGVSVIGVGTDASGMLPDQLGAALARRPAAVFLQPRALNPTGASWSPSRAHALAAVLSGHPQVYVVEDDSAGDLSAGPLRSLGAHLPRQVVHVRSFSKSHGPDLRLAAVSGPATVLDPILERRLLGQGWTSRLLQHLLLSLLTDPASVRAVRAARDEYARRRHLITSGLAAHGITLPPGEGLNVWLPVQDEQAALLSLATAGIGAAAGTAFAVGPAAEPHLRVTVGLVADGHEEVSAQLARAARAATPGIPR
>NC_017093.1|WP_041829883.1|3938040_3939531_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase
MSHIAHWVSGSETPGTSGRVGPVFNPATGEQIATVDLASKAEVDAVVAVAAAAAKQWRAASLSKRSAVLFKFRELLAAHSGELARIVTTEHGKVLADAAGEIARGLENVEFATGIPNLMKGSFSEQAATGVDVYSIRQPLGVVAGITPFNFPAMVPLWMCATAIAAGNAFVLKPSEKDPSASLFLARLWKEAGLPDGVFNVVHGDKEAVDAILLNPEIAAVSFVGSTPIAKYIYETGTAQGKRVQALGGAKNHMIVLPDAELDAAADAAISAGYGAAGERCMAISVVVAVGDIADPLVDAIAARIPKIKIGDGADPASEMGPLISAQHRDKVAGYVAAGASEGATVVADGRETTDISDKGFFLGATLLDNVTPEMTVYTDEIFGPVLSVVRVGTYAEAVQLVNDNEYGNGTAIFTRDGGAARQFQFDVNAGMVGVNVPIPVPVAYYSFGGWKASLFGDTHMYGPDGIHFFTRSKVVTSRWPDPGTSSIDLGFPQTR
>NC_017093.1|WP_014443873.1|3939541_3940879_+|aspartate-aminotransferase-family-protein
MTNEAQVRADDRAHVFHSWSAQGLIDPLPIEKALGSHFWDYTGKKYLDFSSQLVNINIGHQHPRLVAAIQEQAAKLCTIQPAFANDKRGEAARMIAEVAPDGLNKVFFTNGGAEANENAIRMARLHTGRHKVLSTYRSYHGSTATAITATGDPRRWPNEPVAIGVVHFWGPYPYRSPFFSANEQQESERALQHLRDTIVFEGPGTIAAILIETVVGTNGILVPPPGYLAGVRAICDEFGIVFIADEVMAGFGRCGEWFAIDRWGVTPDLITFAKGVNSGYLPLGGVIISDAIAETFRERPFPGGLTYSGHPLAAASAVASMQIFKEEGVIEHARMLGEDVIGPALSEIAAKHPSVGEVRGLGVFWAVELVKNEDKTPLVPFNAAGKDAAPMNAVAAACKERGLWPFVHFNRIHVVPPCTTSVDEVREGLAILDEALTAADGYTTG
>NC_017093.1|WP_014443874.1|3941017_3942469_+|gamma-aminobutyraldehyde-dehydrogenase
MNRKAPSFVSTVLRNFVGGSYSDTADGITTPVIDPSTGEAYAQAPVSSPRDVERAVASAAEGFEVWRDSTPAERQRALLRIADAVEARAEEIIAAECRNTGKPVAATRQEEMAPILDELRFFAGAARILEGKSAGEYLRDHTSFVRREPIGVVAQIAPWNYPMVMAVWKFAPAIAAGNAVVLKPSDTTPVSTLLLAEIAAEFLPPGVLNVVCGDRDTGRALVAHPTPQLVSITGSTRAGMEVAASAAPDLKKVHLELGGKAPVVVFDDVDIEATAAAIAGAGFFNAGQDCTAATRVLVHERIAADFTAALAAAARATKAGPPSDTEAYFGPVNNANQLDRVTGFLGRTPDHADVVAGGNRIGDRGYFLEPTVVTGLRQQDEMIQDEIFGPVITVQSFTDEQQAVRWANDVRFGLSASVWTQNHGRAMRVSRRLDFGAVWINTHLPFVSEMPHGGYGHSGYGKDLSLYGFEEYTRIKHVMSFNG
>NC_017093.1|WP_014443875.1|3942516_3943674_+|ABC-transporter-ATP-binding-protein
MTTSPPHHATSAPTGDGQRAGHPAIEFAGVRKDYLSHGEAVPAVKSLDLAIGQGEFFSLLGPSGCGKTTTMRMIAGFEEPTAGKVFLDGQDVTGVAPNKRDVNMVFQSYALFPHLNVLQNVAFGLERKKVAKSEIRRRVGEILEIVSLTGMEKRQPKEMSGGQQQRVALARALVNHPRALLLDEPLGALDLKLRQQMQVELKRIQREVGITFVYVTHDQGEALTMSDRIAVMNGGLIEQLGSPRAIYERPASRFVAGFIGTSNLIDGQVSWVENGLGVIDLGSGERVLMPLPASVAAGRAIEVSVRPEKIDLHRSAPHAPGLSVVSGTVSEVVYHGTSTNYTVATTAGSDFVVFDQNAHDAEDVASRGERVFLTWAPQHSYPIGV
>NC_017093.1|WP_014443876.1|3943718_3944930_+|spermidine/putrescine-ABC-transporter-substrate-binding-protein
MTQRRFGRRDAMRLGGMSAMGAFLAACGVEGQGKPQASVAPDAVAKFWNGKVKNGTVDFANWPLYMDPKRPELKKFTAKTGIKINSYDEVIQEMGPWFAKVQPQLSAGQSIGYDLMVITNSIQFGQFRDAGFLAPLDHSKLPNYVANAAKSYSQSAYDMGNVFSIPWASGITGIAYDEKKTGRPITKLADLWDPAFKGKVGMFRDLQELGNFGLLAAGIKPGESGEAEWKKAAAKLREQKDAGIVRQYYDQTYIDALGKGEVWITQAWSGDIFQKNVSDGTDFKFVVPEEGGTIWTDNMTIPITAANPVDAITLMDFFYEVENAATLAEYINYVCPVPGAQAVMKKHAAEASGEDKEYLTSVAESPLVFPSEADYAKLHYYVDFNTAEEQQDFSKIFDPIVLG
>NC_017093.1|WP_014443877.1|3944933_3945797_+|ABC-transporter-permease
MGRVKRTLAPYLLVLPGGLWLLMFFAVPMATMLSLSLQEGDIVNGYVFTGHWQTYVEAISDYQTQLIRSLVYGVIATIILIVLAFPAAYWIAFYGGKRKATYLFLLLLPFFVSFVLRTISWRLILTDDGFLLSPLKDVGLLPENFHILGTSAAVIGGLVYNFLPFMVLPIYVALERIDPRVVEAARDLYATPITAFRKVILPLALPGVFAGVLMTFIPVSSDYVNSEVLGSSSTTMIGQVIQSQYLSSSNYPTASALSFTLMAVLLVGVFSYARALGTEDVMKVATR

Crispr_ID: NC_017093_13

• CRISPR_ID: NC_017093_13
• CRISPR_location: 4002878-4003016
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_017093_13

Consensus_repeat	Method
CGTCAACGCGACTCAACCCGTCAAC	CRISPRCasFinder

spacers of NC_017093_13

>13.1|4002903|35|NC_017093|CRISPRCasFinder
TGAGCCGAACGACTTGTGAACACCGGTCACTTCAA
>13.2|4002963|29|NC_017093|CRISPRCasFinder
GCGACTCAACCCGTCAACGCGACTCGACA

CRISPR arrays and Neighbor proteins around NC_017093_13

CRISPR arrays

The CRISPR arrays of NC_017093_13

>merge|NC_017093|13|4002878-4003016|CRISPRCasFinder
GGTCAACACCACGCAACACGTGCAGTGAGCCGAACGACTTGTGAACACCGGTCACTTCAACAACGGGTCTGCTCAACCCGTCAACGCGACTCAACCCGTCAACGCGACTCGACACGTCAACGCGACTCGACACGTCAAC

>NC_017093|13|13|4002878-4003016|CRISPRCasFinder
GGTCAACACCACGCAACACGTGCAG	TGAGCCGAACGACTTGTGAACACCGGTCACTTCAA
CAACGGGTCTGCTCAACCCGTCAAC	GCGACTCAACCCGTCAACGCGACTCGACA
CGTCAACGCGACTCGACACGTCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_172666604.1|4011210_4012587_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|226121
NC_017093.1|WP_014443920.1|3998073_3999015_-|NADP-dependent-oxidoreductase	unknown	unknown	gnl|CDD|176191
NC_017093.1|WP_014443921.1|3999119_3999491_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224647
NC_017093.1|WP_172666681.1|4003087_4004002_-|amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|223836
NC_017093.1|WP_014443923.1|4000497_4001193_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|117022
NC_017093.1|WP_014443927.1|4004107_4005160_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014443922.1|3999546_4000476_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NC_017093.1|WP_014443924.1|4001189_4002170_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270225
NC_017093.1|WP_014443915.1|3990688_3992554_+|AMP-binding-protein	unknown	unknown	gnl|CDD|341271
NC_017093.1|WP_157435359.1|3992727_3994356_-|sulfatase	unknown	unknown	gnl|CDD|293739
NC_017093.1|WP_014443934.1|4010131_4011163_-|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NC_017093.1|WP_014443928.1|4005233_4005455_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014443918.1|3995648_3996926_+|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274819
NC_017093.1|WP_014443929.1|4005499_4005691_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014443933.1|4008369_4010049_-|glycoside-hydrolase-family-13-protein	unknown	unknown	gnl|CDD|200471
NC_017093.1|WP_014443932.1|4007193_4008270_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014443919.1|3996932_3998054_+|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274646
NC_017093.1|WP_014443917.1|3994633_3995656_+|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274819
NC_017093.1|WP_014443931.1|4006295_4007096_-|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|252734
NC_017093.1|WP_157434927.1|4005795_4006182_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_172666604.1|4011210_4012587_-|AAA-family-ATPase	gnl|CDD|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	6.19739e-11
NC_017093.1|WP_014443920.1|3998073_3999015_-|NADP-dependent-oxidoreductase	gnl|CDD|176191	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases. Members identified as zinc-dependent alcohol dehydrogenases and quinone oxidoreductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	9.64869e-124
NC_017093.1|WP_014443921.1|3999119_3999491_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	1.03722e-37
NC_017093.1|WP_172666681.1|4003087_4004002_-|amino-acid-ABC-transporter-permease	gnl|CDD|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.34806e-60
NC_017093.1|WP_014443923.1|4000497_4001193_-|GNAT-family-N-acetyltransferase	gnl|CDD|117022	pfam08445, FR47, FR47-like protein. The members of this family are similar to the C-terminal region of the D. melanogaster hypothetical protein FR47. This protein has been found to consist of two N-acyltransferase-like domains swapped with the C-terminal strands.	9.87947e-25
NC_017093.1|WP_014443922.1|3999546_4000476_+|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	3.37592e-52
NC_017093.1|WP_014443924.1|4001189_4002170_-|ABC-transporter-substrate-binding-protein	gnl|CDD|270225	cd01004, PBP2_MidA_like, Mimosine binding domain of ABC-type transporter MidA and similar proteins; the type 2 periplasmic binding protein fold. This subgroup includes the periplasmic binding component of ABC transporter involved in uptake of mimosine MidA and its similar proteins. This periplasmic binding domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.51931e-71
NC_017093.1|WP_014443915.1|3990688_3992554_+|AMP-binding-protein	gnl|CDD|341271	cd05967, PrpE, Propionyl-CoA synthetase (PrpE). EC 6.2.1.17: propanoate:CoA ligase (AMP-forming) or propionate#CoA ligase (PrpE) catalyzes the first step of the 2-methylcitric acid cycle for propionate catabolism. It activates propionate to propionyl-CoA in a two-step reaction, which proceeds through a propionyl-AMP intermediate and requires ATP and Mg2+. In Salmonella enterica, the PrpE protein is required for growth of Salmonella enterica on propionate and can substitute for the acetyl-CoA synthetase (Acs) enzyme during growth on acetate. PrpE can also activate acetate, 3HP, and butyrate to their corresponding CoA-thioesters, although with less efficiency.	0
NC_017093.1|WP_157435359.1|3992727_3994356_-|sulfatase	gnl|CDD|293739	cd16015, LTA_synthase, Lipoteichoic acid synthase like. Lipoteichoic acid (LTA) is an important cell wall polymer found in Gram-positive bacteria. It may contain long chains of ribitol or glycerol phosphate. LTA synthase catalyzes the reaction to extend the polymer by the repeated addition of glycerolphosphate (GroP) subunits to the end of the growing chain.	6.18536e-16
NC_017093.1|WP_014443918.1|3995648_3996926_+|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274819	TIGR03860, FMN_nitrolo, FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family. This model represents a distinctive clade, in which all characterized members are FMN-binding, within the larger family of luciferase-like monooxygenases (LLM), among which there are both FMN- and F420-binding enzymes. A well-characterized member is nitrilotriacetate monooxygenase from Aminobacter aminovorans (Chelatobacter heintzii), where nitrilotriacetate is a chelating agent used in detergents. [Unknown function, Enzymes of unknown specificity].	6.81894e-143
NC_017093.1|WP_014443933.1|4008369_4010049_-|glycoside-hydrolase-family-13-protein	gnl|CDD|200471	cd11332, AmyAc_OligoGlu_TS, Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), trehalose synthase (also called maltose alpha-D-glucosyltransferase), and related proteins. Oligo-1,6-glucosidase (EC 3.2.1.10) hydrolyzes the alpha-1,6-glucosidic linkage of isomaltooligosaccharides, pannose, and dextran. Unlike alpha-1,4-glucosidases (EC 3.2.1.20), it fails to hydrolyze the alpha-1,4-glucosidic bonds of maltosaccharides. Trehalose synthase (EC 5.4.99.16) catalyzes the isomerization of maltose to produce trehalulose. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NC_017093.1|WP_014443919.1|3996932_3998054_+|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274646	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1. The Pfam domain family pfam00296 is named for luciferase-like monooxygenases, but the family also contains several coenzyme F420-dependent enzymes. This protein family represents a well-resolved clade within family pfam00296 and shows no restriction to coenzyme F420-positive species, unlike some other clades within pfam00296. [Unknown function, Enzymes of unknown specificity].	2.49438e-109
NC_017093.1|WP_014443917.1|3994633_3995656_+|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274819	TIGR03860, FMN_nitrolo, FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family. This model represents a distinctive clade, in which all characterized members are FMN-binding, within the larger family of luciferase-like monooxygenases (LLM), among which there are both FMN- and F420-binding enzymes. A well-characterized member is nitrilotriacetate monooxygenase from Aminobacter aminovorans (Chelatobacter heintzii), where nitrilotriacetate is a chelating agent used in detergents. [Unknown function, Enzymes of unknown specificity].	1.79807e-51
NC_017093.1|WP_014443931.1|4006295_4007096_-|SAM-dependent-methyltransferase	gnl|CDD|252734	pfam04672, Methyltransf_19, S-adenosyl methyltransferase. This family contains a SAM (S-adenosyl methyltransferase) domain, with a central beta sheet with 3 alpha-helices on both sides. Crystal packing analysis of the structure Structure 3giw suggests that a monomer is the solution state oligomeric form. An unidentified ligand (UNL, cyan) was found at the putative active site surrounded by the residues His57, His170, Phe171, Tyr216 and Met22. The UNL is likely to be a phenylalanine or phenylalanine-like molecule. (details derived from TOPSAN).	6.30891e-110
NC_017093.1|WP_014443934.1|4010131_4011163_-|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	3.04408e-92

Protein sequences

>NC_017093.1|WP_014443924.1|4001189_4002170_-|ABC-transporter-substrate-binding-protein
MRTRWVLALAAVTLSLAACAAPEEEQAVVPAAGDASAATTVTFNDSPEQNRITPPKDDAAAALLPPDVAKSGKLVIGVGAAGSGFPPLAFAASDNKTLIGNEPDIAVAIASTLGLEPVLENTSWENLFIGLDSGKYQLGASNITVTEERKLKYDFVSYRKDDLGWLAKKGSGLTVTKPADIAGKKVAVGSGTNQEKILVEWADEVKKAGLAPVEIKYYQTNQATYLALGSGQIDLYLGPNPSAAYHVATTGQTEIVGTYSGAGAGLQGLIALTTKKDNGLVKAYAAALDKLIASGDYTKILQRWNLTNEGVTAAEVNPPGLPIEGK
>NC_017093.1|WP_014443923.1|4000497_4001193_-|GNAT-family-N-acetyltransferase
MTGAVVASVLDNPAWSSLAGAHARFAVLHGQAARYQSDVAPFHALADPADPQAWDDLTALVEPGAAVTIAGAGGVAYRGWEVAGSIPGVQLVDVALRASPSPDAYRLGAGDVPEILDLIERTRPGPYLRRTVELGAYLGLRSPAGALIAMAGERLHPAGWTEISAVCTDPAHRGRGLATRLVRAVAAGIRERGETPFLHTSAANVTAIRLYESIGFELRKQTDFTAYRRLS
>NC_017093.1|WP_014443922.1|3999546_4000476_+|LysR-family-transcriptional-regulator
MELRQLSYVEAVARYGGFTRAAERLHVAQSAVSAQIKALEAELGLALFARTTRRVALTPAGELFVARARRVLAELDGARTEIHEITSVVHGRVSIGATAALGPYDLPQALTRFRDRFPGIAVRLRSGLVTGLLGALDEGELDLVVGPVHADLPPRFDALPLADEHLLLALPIGHALSRAGRLTLGEARDEPFVSLPPGSGLRWILEDAARSAGFTPRVEFETASPAGIRDLVAAGLGVGLLSKSVAEAPGPAITIRSLHPAPVHPPIGVMHSRDRPLSPAAQSCRHHLVEVAGLQPDPSHRPDPTEEPL
>NC_017093.1|WP_014443921.1|3999119_3999491_+|helix-turn-helix-transcriptional-regulator
MPTACATGHHDHHDVYAQLCPCRHLLDLIANKWTTLAVGALEDGPQRFGVLQRTLEGVSPKVLTQTLRRMEEAGLVTRTVYPAVPLHVEYELTEVGHSLNVPLRALRHWAENHLDETRVVSPG
>NC_017093.1|WP_014443920.1|3998073_3999015_-|NADP-dependent-oxidoreductase
MRAITQQRFGGAEVLQVAEVPRPEPLPTEVLVRVVAAGLNPVDVKTREGGGMAGVLGEPPFILGWDVSGVVEAVGFGVHTLKPGDEVYGMPWFPRQAGGYAEYVTAPSRHFARRPLSISHEASAAVPLAALTAWQALTAATTVKPGQRVLIHAAAGGVGHFAVQFAKHLGAHVIGTARSGKHAWLRSIGADEVVDYTAVRFEDAVRDVDLVIDLVGDEETGLRSLETLTPGGLLIAVPSGVAGSIVEAAGRSGKSAIPFLVESDGPALAEIGRLIDAGVVRVEVAEVFPLDRAGEAHRALETGRTRGKIVLTV
>NC_017093.1|WP_014443919.1|3996932_3998054_+|LLM-class-flavin-dependent-oxidoreductase
MSVPLSVLDLSPLVSGDDGPADALRRTLDLARNAEQFGYHRYWVAEHHFTPGVASSQPALLLGQIAAVTDNIRLGSGAVQTGHQTALTIVEQFGLLDALYPGRFDLGIGRSGQAKNEVLREEAKHAEPQEERIVDGLLIPKPFSWAPIFASQRTALASSLLTLPGASSLPLNEVLDQIVALLAGPVGDGEGNEVTAVPGAGADLEVWLLGSSGGESARTAGARGLPFAANYHVAPAKVLEAADAYRESFVPSATLSAPRLMVSADVLVAEDDETARRLAAPFARWVHSIRTGFGAVPFPSIEEADGYAWTAEARALVADRVDTQFVGSPQTVAERLRTLQRVTGADELLITTIAHRHADRVRSYELLAKEWHG
>NC_017093.1|WP_014443918.1|3995648_3996926_+|LLM-class-flavin-dependent-oxidoreductase
MPKQIILAAHFPGVNNTTVWSDSRSGSQIEFDSFEHLARTAERGRFDFFFLAEGLRLREQRGLIHDLDVVGRPDTLTVLAALAAVTTHLGLAGTLNATYHEPYELARQLATLDHLSGGRAAWNVVTSPGAFFGENFRRGGFLDHADRYVRAAEFIEAARTLWDSDGGDFSITSSQFGIAGRFGVPRSPQGHPVVLQAGDSEGGRELAARHADAIFSRHHQLEDARVFYRDVKQRVIRHGRDPDSLKIIPGVSYVLGDSDADAQEKAHHIRRQQVSPQTAILLLEQLWNRDLSGYDADGPLPEIDPRLDEDDTIIKGRAGMYPDRLATAAEWRALAEAKKLSIRDLIIEVTGRQNFIGTPARVAEQLDEYVQTGACDGFILVPHLTPAGLDDFVDQVVPLLQERGVVRTEYSGGTLRDNLGLAKGR
>NC_017093.1|WP_014443917.1|3994633_3995656_+|LLM-class-flavin-dependent-oxidoreductase
MTLQLAVALDGDSFAAADWVGWARQADEALLDFVTFDDRFGRRGPDAVLTAARVAPLTRHVGLVPVATTTHTEPFHLSTALATLDYASRGRAGWQVRISGDPAEAALLGRRPPLGADELFEEAVDVVEVVRRLWDSWQDDAIIKDVATGRFIDRDRLHYIAFDGRYFSVKGPSIVPRPPQGQPVVAALAHGPAAWQFAGTAADLVFITPADAGDAAKIKSRLDPELKVFADIAVFFGPGAAPSDAAVFTGTVPQLADLIGAWAGSGIDGIRLRPGLLGRDLGEITRELVPELRRRSLFAPSAAVTLRERLGLPVAINRYERPAASGGAEGAPRPEGVPVA
>NC_017093.1|WP_157435359.1|3992727_3994356_-|sulfatase
MLGHPRFQLALTVLACVIVFAALVYPNVLKRLTVGGFARIPIEAALGIALLIAVPRRPRRILATVAGLALGWLIVEKSLDMGWFEILNRPFDPVLDWILFDDTYGFIRDSYGQASAYGAIAAVVLLPIAVLSLTTWAVLRVTSLIGRHRRISAYTASGIAAAWIAAFLVGVQVVPKVPIAARSSVTYAYDRARQAKAGIANSAAFAKEIKNDPFKNTPADRMLTGLAGKDVIFTFVESYGRNAVESPELAPGVDAVLDSGTAQLTAAGFAARSGWLTSPTFGGGSWLAHSTLLSGLWINNQSRYRNLTASDRLTLTSAFRGAQWDTVSVMPGATRAWPEGKFYGYNRVWDSRNLGYQGPKFSWAPMPDQYTLKKFTELEYAKPGRQPLMVEMPLVSSHTPWAPIPSFMDWEKVGDGSVYDGIVANGTKKADIWGSTSKVRAEYGKSIQYTLTTLVDWVKTYGDDNLVLVFLGDHQPSKVISGENASHDVPITVVAKDPAVLKRIDSWGWTDGLKPATDAPVWPMNAFRDKFFTAYGPNGSTH
>NC_017093.1|WP_014443915.1|3990688_3992554_+|AMP-binding-protein
MANYREAYTRSITDPDGFWRDAASAIDWERSPDKILDDTEAPIFRWFSDGTLNTCWNALDRHVETRGDQPALIYDSPVTTVVRSYTYREMRDQVALFAGALRRIGVEAGDRVVIYMAMVPEAVVAMLACARIGAVHSVVFGGFGARELAARIDDARPKVIVASSGGIEAGRIVAYQSMLDAACDEATHVAERRIILQRPQAPFDLRDGDLTWEDALDGAEPAGCVPVRATDPLYILYTSGTTGRPKGVVRDNGGHAVALRWSMENIFGVRPGDVFWAASDVGWVVGHSYIVYAPLLTGATTILYEGKPVATPDAGAFWRVAEQHRVSVLFTAPTAIRAIRREDPDGRLTAGRDLSDLRLLFLAGERLDPPTYTWAGDLLGIPVIDNWWQTETGWPIAASPRGIEELPTRPGSPSVPMPGYRVRVVDSTGADVPAGQEGSIVIGLPLPPGCLPTLWGDDERFVRSYLSTFQGNYLTGDGGRFDDDGYLYVLGRTDDVINVAGHRLSTGSMEEVLSAHPAVAECAVIGVSDPLKGQVPRGLVVAKAGVTVDPAELVAFVRERIGAVAALRRVDVVTALPKTRSGKILRGTMRGIADGRDEAVPSTIENPDVLDALRPVLRRQH
>NC_017093.1|WP_172666681.1|4003087_4004002_-|amino-acid-ABC-transporter-permease
MTPIQPKNAGPPADDDILTVVPARHRWRWAGTALVVVLLAQFVHGLATNPGWDWSTFAGYFLEKSVMEALLVTLQLTVAGAILGFLGGIPLAAMRLSKNPVLSTVSWGYIWVFRSVPLLVQLLFWANLGYLYDRLQIGIPFGPGWSFATADLISPFGAALLGLALHEAAFAGEIIRAGLLSVDQGQHEAAAALGIPKRRQFFTIVVPQAMRAILPNAANLLVNLLKSTSIVYVLAIGELFYQVQVIYGRSGRVVPLLMVATVWYVILTAALSILQYYTERYFARGAVRTLPPTPFQRLKAVLSR
>NC_017093.1|WP_014443927.1|4004107_4005160_-|hypothetical-protein
MPVLTRPAVLLAAASVAAGLIVAPSAAHASPQSPVAATASGAADTTTTLSAAEMAAAMKQVAAASTTAGAGGWRADQKYAVDAPGTIGSFSGTSTTVVDPIKGLFTDTFTTAGYGSVTTFAAAGRGVYESVGDPEQVAALKMMKRTAVKYAFTADPKLTLAAHVAENAQSPQSVAAEFTDAATRVAHADGTADYTAVDQEGAFVTLNVDATGALTGAHAELEGEDGASEVTLAYAYGPQAVTLPAASATIGSAALATGVAYLSMDAVVRTVANSGATAARKAAKGKKVKVTALRTVIRKNVTAHNRSAAVAVKVSNVTGGVKVQATNPWTRKTTAYTVKASGTKVVVKKA
>NC_017093.1|WP_014443928.1|4005233_4005455_-|hypothetical-protein
MQWLLWAALAAAIVTILVIILLFARDLRRSRRAPGTPPPTRGGKRPDDTWARNIMNTDDTRGGGDSGFTGGGF
>NC_017093.1|WP_014443929.1|4005499_4005691_+|hypothetical-protein
MSDLNPDNFAEFTTQDGPGSPESDEERLSPPPEQEAHGGSMAPGLVDDTGARTAEDFPGERDL
>NC_017093.1|WP_157434927.1|4005795_4006182_+|hypothetical-protein
MSGGHPRRSIIPESAAVDEGMAGFMGFMGWINLVMSLIGACSLCLGIRALATGKLPRRLSEQYRDPVAGGRYLVGFGLFCLLQVVGYLGVEFGLFGSLVRGAIVVLAFVLAAVTVLLHRRRRDVTSRP
>NC_017093.1|WP_014443931.1|4006295_4007096_-|SAM-dependent-methyltransferase
MTDNDAKLDTSVPHSARVWNYWLGGKDNYQVDRQVGDDFANLYPDIAVVARQSRAFLKRAVTHLVTDKGVKQFLDIGTGMPTAENTHQVAQAAAADCKIVYVDNDPLVLVHARALLTGTAEGRTEYVDASLHDPRAILEAARGTLDLDQPVGLILMNILGHVPDLDQAVSIVRALLDGLPSGSYLVTADGTNVIDGPAFEEAIGVWNANAPLSYNLRHPDQISRFLEGLEVLEPGLVPCAEWRPDAGATGDEARAVDEYGAVGRKR
>NC_017093.1|WP_014443932.1|4007193_4008270_-|hypothetical-protein
MMVSSYSLTLPTESAARAVADQLADRGHWLVAVRAVGHFSTDTHRPEFAGWWDVYSVVTTEPAPAGAETAAVRQIARHHGGVTAGPGGGKIEGLSRFFNREGLVHELSADEAARRRPAVVPPGPTVVPPAPLAYRETPDEAAELAAIMEALAGDDEPWEEDDDEPADSGDLLGELFNAAMHQGTVYAHTAGTVPDFVALALDERLGDQARAWVYLDLFMISTVGRRYLCSTADREHAFGRPLEESPDAVAARQAVMAGLPRLLRRWDAEVEIGRFFLAALVAAEPEAGAGLRRAIGELRRGYAGTARERTLLLVEALADRDEQRIEEALGDLGTGLSPWATAEQRGLSVLEDLLTAEV
>NC_017093.1|WP_014443933.1|4008369_4010049_-|glycoside-hydrolase-family-13-protein
MTDQLIAPPAVEAPPASWWRNAVIYQIYPRSFADSNGDGIGDLPGILSRLPYLRDLGVDAVWLSPFYSSPQADAGYDVSDYRTVDPIFGTVADAEKLIAGAHELDLRVIVDLVPNHSSDQHEWFKRAIAEGPGSPFRDRYHFRPGKGENGELPPNDWPSIFGGPAWTRVEDGEWYLHLFAPEQPDFNWEHPAVRDEFKTILRFWLDLGVDGFRVDVAHGLVKEDGLPDVGHAAEWHLLGVGESPCFDRDGVHEIYREWRKILDEYPGERIAVAEAWAPTLARVADYVRDDELHQAFNFSYLGTAWNVPAQQQMIDDSLAAMRVVGAPTTWTLSNHDVVRHSNRLLQTGDGEVAGRRPTAVDPVAGLRRARAASALMLALPGSAYLYQGEELGLPEVVDLPPEVRQDPAFHRATGQDGYRDGCRVPIPWSGTEAPYGFGPDGGGSWLPQPDSWAQLSVAAQEGVPGSTLELYRAALAVRRGMPALAPTDNLRWVPAPDGVLAFERAVEGRPVFRCTVNMSGQPVAVGRPGELLLSSGALDGTADNVVLPPDTTVWWSIQD
>NC_017093.1|WP_014443934.1|4010131_4011163_-|LacI-family-DNA-binding-transcriptional-regulator
MRSRKPTSSDVAAAAGVSRSAVSFAFNNPQRIAAATRERILSVAEDLGYRPSTLGRMLQAGTTNSIGVLFPQRLAQVMENPYYSRFLMGAGQVCDREGYTLLLTPPLQDSVLKAIPYAAVDGFIVCGLEVDRGEVAELDRRGIPFVLIDSDRHEGAPSVEVDDRGGAGEVARYLLELGHRRLAVLSIDPGPRVSERGYRGPLARRLAGISDALADFGLDLSDVRLAEVPVTRTDGYRATQDLMAQPDPPTAIVALSDVLAYGAVDALQELAVDVPSAVSVTGFDDLAESAWFRPRLTTVRQPIVTKGRIAADFLISAIRGEDQHPHQMLGTSLIIRDSTAKPA
>NC_017093.1|WP_172666604.1|4011210_4012587_-|AAA-family-ATPase
MIEQDVGARMPAAGSTSHRPAAPQTSSRLKNSSRVLGGRPKTWHWPERGRPVRPAQLKHVIGTLGQPAVPIVHFGARPDPHGRSEHRRRGDLGTGVEQVLLAAVIGIAQPAATFVAIEEPETALHPAAQRAMLGLFRRWSSDRVFALTTHSPIFLDSQHADTYLLRRSGGESSIEKAESGLGDVLAALGVRSSDVLSAERILLVEGPSDRDVLAAWFPELLEDPRNVVIIGQGGRNARFAGMLDEWIRAADRVERPILYLRDRDELDDDAVTKLRSVPAVHVLERREIENYLLNPETLAVYFAELGKQWDPAPIAHALRQAAGDLRRTVIIKSVVARLDVVRLVDDRERSRLVKRVQTAGDPVEAVLTRVPDRQKLEGQIRQAWLEVEAAIGARWEIDWVTLAPGEEILRAVFQEFLGRGYRKTTDAGGLARCLATPPAEISEVIGGFLGERRLPRTQ

Crispr_ID: NC_017093_14

• CRISPR_ID: NC_017093_14
• CRISPR_location: 4150319-4150391
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_14

Consensus_repeat	Method
GACCGCCGCCGTCACCCGGGCCC	CRISPRCasFinder

spacers of NC_017093_14

>14.1|4150342|27|NC_017093|CRISPRCasFinder
TGTCACCGACGACGGGAAGGCTTGCTT

CRISPR arrays and Neighbor proteins around NC_017093_14

CRISPR arrays

The CRISPR arrays of NC_017093_14

>merge|NC_017093|14|4150319-4150391|CRISPRCasFinder
GACCGCCGCCGTCACCCGGGCCCTGTCACCGACGACGGGAAGGCTTGCTTGACCGCCGCCGTCACCCGGGCCT

>NC_017093|14|14|4150319-4150391|CRISPRCasFinder
GACCGCCGCCGTCACCCGGGCCC	TGTCACCGACGACGGGAAGGCTTGCTT
GACCGCCGCCGTCACCCGGGCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_014444068.1|4157936_4158917_-|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|379770
NC_017093.1|WP_041831034.1|4159011_4159803_+|PrsW-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|379143
NC_017093.1|WP_014444066.1|4156272_4157082_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_157434936.1|4160472_4160982_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014444058.1|4145515_4147003_-|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|143635
NC_017093.1|WP_063711161.1|4149270_4150299_+|nitroreductase-family-protein	unknown	unknown	gnl|CDD|236122
NC_017093.1|WP_014444057.1|4144061_4145567_+|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|366009
NC_017093.1|WP_014444064.1|4151876_4152476_+|DivIVA-domain-containing-protein	unknown	unknown	gnl|CDD|377456
NC_017093.1|WP_083888662.1|4157059_4157986_+|DMT-family-transporter	unknown	unknown	gnl|CDD|223769
NC_017093.1|WP_014444059.1|4147040_4147700_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|172294
NC_017093.1|WP_014444052.1|4138214_4139303_+|glutamate--cysteine-ligase	unknown	unknown	gnl|CDD|237408
NC_017093.1|WP_157434934.1|4140260_4142552_-|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|238923
NC_017093.1|WP_014444063.1|4150945_4151425_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|224167
NC_017093.1|WP_014444065.1|4152552_4156164_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|380075
NC_017093.1|WP_157434935.1|4143514_4144063_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224759
NC_017093.1|WP_014444060.1|4147777_4149220_+|MFS-transporter	unknown	unknown	gnl|CDD|184957
NC_017093.1|WP_014444072.1|4162384_4163911_+|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha	unknown	unknown	gnl|CDD|236507
NC_017093.1|WP_014444055.1|4142538_4143219_+|HAD-family-hydrolase	unknown	unknown	gnl|CDD|223620
NC_017093.1|WP_051042067.1|4161322_4162195_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|369561
NC_017093.1|WP_083888815.1|4139330_4139966_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_014444068.1|4157936_4158917_-|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|379770	pfam16113, ECH_2, Enoyl-CoA hydratase/isomerase. This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.	3.67255e-154
NC_017093.1|WP_041831034.1|4159011_4159803_+|PrsW-family-intramembrane-metalloprotease	gnl|CDD|379143	pfam13367, PrsW-protease, Protease prsW family. This is a family of putative peptidases, possibly belonging to the MEROPS M79 family. PrsW, appears to be a member of a widespread family of membrane proteins that includes at least one previously known protease. PrsW appears to be responsible for Site-1 cleavage of the RsiW anti-sigma factor, the cognate anti-sigma factor, and it senses antimicrobial peptides that damage the cell membrane and other agents that cause cell envelope stress, The three acidic residues, E75, E76 and E95 in Aflv_1074, appear to be crucial since their mutation to alanine renders the protein inactive. Based on predictions of the bioinformatics programme TMHMM it is likely that these residues are located on the extracytoplasmic face of PrsW placing them in a position to act as a sensor for cell envelope stress.	2.61873e-21
NC_017093.1|WP_014444058.1|4145515_4147003_-|GGDEF-domain-containing-protein	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	2.87676e-49
NC_017093.1|WP_063711161.1|4149270_4150299_+|nitroreductase-family-protein	gnl|CDD|236122	PRK07877, PRK07877, Rv1355c family protein.	9.09529e-27
NC_017093.1|WP_014444057.1|4144061_4145567_+|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|366009	pfam00296, Bac_luciferase, Luciferase-like monooxygenase.	5.67234e-40
NC_017093.1|WP_014444064.1|4151876_4152476_+|DivIVA-domain-containing-protein	gnl|CDD|377456	pfam05103, DivIVA, DivIVA protein. The Bacillus subtilis divIVA1 mutation causes misplacement of the septum during cell division, resulting in the formation of small, circular, anucleate mini-cells. Inactivation of divIVA produces a mini-cell phenotype, whereas overproduction of DivIVA results in a filamentation phenotype. These proteins appear to contain coiled-coils.	8.20981e-11
NC_017093.1|WP_083888662.1|4157059_4157986_+|DMT-family-transporter	gnl|CDD|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	4.94322e-19
NC_017093.1|WP_014444059.1|4147040_4147700_-|TetR-family-transcriptional-regulator	gnl|CDD|172294	PRK13756, PRK13756, TetR family transcriptional regulator.	2.74584e-10
NC_017093.1|WP_014444052.1|4138214_4139303_+|glutamate--cysteine-ligase	gnl|CDD|237408	PRK13517, PRK13517, glutamate--cysteine ligase.	4.51326e-113
NC_017093.1|WP_157434934.1|4140260_4142552_-|EAL-domain-containing-protein	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.29588e-99
NC_017093.1|WP_014444063.1|4150945_4151425_+|GNAT-family-N-acetyltransferase	gnl|CDD|224167	COG1246, ArgA, N-acetylglutamate synthase and related acetyltransferases [Amino acid transport and metabolism].	3.74717e-10
NC_017093.1|WP_014444065.1|4152552_4156164_-|alpha/beta-hydrolase	gnl|CDD|380075	pfam17957, Big_7, Bacterial Ig domain. This entry represents a bacterial ig-like domain that is found in glycosyl hydrolase enzymes.	3.69772e-10
NC_017093.1|WP_157434935.1|4143514_4144063_-|MarR-family-transcriptional-regulator	gnl|CDD|224759	COG1846, MarR, Transcriptional regulators [Transcription].	1.52165e-17
NC_017093.1|WP_014444060.1|4147777_4149220_+|MFS-transporter	gnl|CDD|184957	PRK14995, PRK14995, SmvA family efflux MFS transporter.	1.26318e-38
NC_017093.1|WP_014444072.1|4162384_4163911_+|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha	gnl|CDD|236507	PRK09424, pntA, Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha.	0
NC_017093.1|WP_014444055.1|4142538_4143219_+|HAD-family-hydrolase	gnl|CDD|223620	COG0546, Gph, Predicted phosphatases [General function prediction only].	9.95465e-23
NC_017093.1|WP_051042067.1|4161322_4162195_+|alpha/beta-hydrolase	gnl|CDD|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	9.66724e-59
NC_017093.1|WP_083888815.1|4139330_4139966_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	2.03517e-27

Protein sequences

>NC_017093.1|WP_063711161.1|4149270_4150299_+|nitroreductase-family-protein
MEATRLVPPSRQILLDCVRAAARAPSLHNSQPWLFRVDPPAVEVFADPARRLPVVDPVGREQLISLGAAVVTLRIAMRKAGYRVRAELSPAQPDMSPVTRSVASPVTGTVASSVASSVAGNVASPVARIIADRPAHADAVTESLAAAIPHRHTNRRPFAQVAVPADAIAQLQDAARQEGATLTVADPTGRDAILGLAREADRWLHERPHYAEEIARWTGQNARHDGVPEWAAGPWDALEVMPVRDFAGAGGPREPFEPYPTIVVLATDGDTPLDWLRAGQALQRVLLTATWLGLATTPISQPVEVPAVRAKLTRRPAQMVLRVGYGRVAGQTPRRPISEMLL
>NC_017093.1|WP_014444060.1|4147777_4149220_+|MFS-transporter
MTSTVLEARATSPATSLRAVWPAILGLSVVFLVEMLDNSVLTVALPTITRELGASATDLQWITSGYSLLFGGLMIAFGAIADRYGTRRMMLLGLSLFALASLAVVAVRTPGELIAVRAAIGVTAAMTAPGTMALCFRLFDQENLLMRATSLIATVGLVGMAVGPTAGGLILQVLPWQTLLVMNVPIAVLAIVCIRRGIPSDDPAKRNTTPLDLPGALLGTVTLILTLWTATLAVEDGWGQAAPWLAGAGAILSAAAFVVRERRTAHPIFDFALIRRPTVSASLAYEAAMGLGMAALAYSVSLQLQLVWGWSPAQAALGNLPQVVVLLAVGPFVEKFAKRLGTQRAGALGAAAVVAGLLVYGLLGRYDYVWIAVALALTAAGMRVVSTIAGVTVMRGLPEDQTSTGAALSDTSQEVAGSIGMAVTGTIVAAAIAGSLTEIGTTGTGAFENAVTTATLVLTAICAALVIWAARRGSSVRDAS
>NC_017093.1|WP_014444059.1|4147040_4147700_-|TetR-family-transcriptional-regulator
MATRTRNTERLSRERIVEAAVELLDTTGEDGLTFRALSAHLRTGPGAIYWHVANKGELLDAATDAVLTRGMTGEAATGTPQEVIRAIALVLFDAIDEHPWVGAQLSDGPWRSVTLQICERIGQQIQRLGVPGAEQFMAASAVMLYILGAARQNAANARMNPPGADRAAILATQAAAWEGLDPEGFPFLRHVAGQMREHDDREQFVAGLDLILVGITGLA
>NC_017093.1|WP_014444058.1|4145515_4147003_-|GGDEF-domain-containing-protein
MRNRLLTRLGVIAVAGLVLQLLLPHLSETAGLVLACAPIAAAGWYAATGFARQTRSHRGRQRLGMAFGAVSGGLLGVSYTLYTVDALTGAQAHLNTLASVTSIAAAVVAVPAILIAVPPFANWLARGTYLIDVATVAGAIFATAWQFALRPAAEALLPGARAQFGLTVSAEILAAALALMLISRTDAGRYRAMRVLAAGLALFALAALISVHNHTDGDAWYAHGLGAVYLIAGLVIAVASRSTLETDESGTRSQFSGMWSTLPHLPVIVALVSVIVPYVRDATLSPVLLGTLLSTSVLAVVRQLLNSLVVRGLVLDLEDQRRRLDHLAHHDMLTGLPNRTAFQVRGEQALTTIRPGTVTGVLLIDLDGFKTVNDTHGHAAGDALLRTAAGRITRALRDGDTAARLGGDEFAVVVPAVKDLGDAVAVGDRILREFAGAAVRGSVGVTVSSVPGRSLDELLHEADTALYAAKAAGKGLVRAYCTPSLAIGSTSSRSS
>NC_017093.1|WP_014444057.1|4144061_4145567_+|LLM-class-flavin-dependent-oxidoreductase
MPDYGHSLEFGTFITPAATDPDRVVALAVLAEQAGLDLVTFQDHPYQAGFLDTWTLLSFVAARTRNVRMSANVINLPLRPPAVLARSVASLDLLSGGRIELGLGAGAFWDAIEAMGGERLTAGQAVQALEEGIEIIRQIWDAETRGGVRVHGDFHRVSGAKRGPAPAHRVGIWLGAYKPRMLALTGRLADGWLPSLGYLKPGDLASGNAIIDEAALAAGREPRDVRRLLNLAGPSHGAEELAELALTEGISTFILAADEPDVIRVFGEEVAPAVRELVTAERSGQAAQLSDKETPKTPIKATNLGVTPTPDTGVRRSTRTPWDESTRPTGPAPDPARTYTPHEQASGRHLVEIHDHLRAELAQIHDLIDQVEAGTMDVGAARSHINTMTMRQNNWTLGTFCESYCRIVTTHHTIEDRSLFPHLKRNDPRLAPVIDRLEQEHHVIHDVLEGVDKALVALVTTDGGGTAGLRAAVDLLSDTLLSHLAYEERELVEPIARLGVQ
>NC_017093.1|WP_157434935.1|4143514_4144063_-|MarR-family-transcriptional-regulator
MIQLCRFTDVLSNRRSVTSCIVADVTTPLEGDLGWMLGVVFRAYAKAAEHALRDLPGGPRGYQVLTAAVGSPPRNQGAIAEDLGIDRTILTYLIDDLEKRDLVVRRPDPADRRSRLIVATETGRASREAHRAALEHVEAHVLASLEPEAAETLRGLLQRVACSAQERDPMSDLCEAVKKIDG
>NC_017093.1|WP_014444055.1|4142538_4143219_+|HAD-family-hydrolase
MVRIMIRAVAIDVDDTLCMTEEASFILENEVLTAMGRPPMPRSLHLQTWGEPLLQAMPKRSPGLDLDRFGPLFHDAMTRHVSDGLLDVIPPENLHALDELLAEGFRLMLLTSRTGPEIRHMLEPDHALSSRITAAYHRDNTRFGKPDPRAFDELLSQAGLAPPECVYVGDSPGDALAAGGAGVAFIACLQSGVRRLSDFDPRYVTASISAFPEVVPTIKTLPGYGG
>NC_017093.1|WP_157434934.1|4140260_4142552_-|EAL-domain-containing-protein
MIRTIEPQLAGVRADVHGDGCCNAGGGAVVTRWRAWYLPIAVVMAVADVALIVLGTRTVFSNLLVWVPAVLGVAMAVANFAAAARGTTGQLRTFWRRLTVAMAFVLVAALSQTVDVMTVRSAGMPPIGSRTLLLYVAGTVLAISAMLRLPGGGRSWRQLTTAVLDVTVVAVTAGIAASEYVGWFMDRFGVSTSAWWLNIAMMAIAVAGVVVVVKIMAARQSPVPRAALWWLAPIGLAGPISTVLMTLLNSWPHLNGSAAVLPFVGLFGTLAAFAQQRPGGHAAPTLHPSFYRRSTAVPLVATGLASVLVATVYLRTGHLSTVQVGGTTLLLLLVVARQAMALSENSTLLDTVAHYAMHDELTGLYSRRYFTAAVAEASGPHTVMLVDLKDFRSINDSLGPAAGDALLIAFAARLSGLVGADAVVARLGGDEFGLLLPGTTAVTIGDEPLHADGHEVIVDLSIGVAEGDDDLFRRAEIALREATVNPGQAVVRYDASLERRLNQRATIAADLRRALSAGEFHLLYQPVVELPGGRMVGVESLIRWRRPDGATVSPADFIPVAEDTGLIVELGAWIIDTVCAQAAAWRHRHGPGALQSVAVNVSARQLLDPSLPDVVATALARHGVPASQLTVEITETAVFGGGRALNTVTALSSLGVSIALDDFGTGHSSLGLLRTCPVDAIKVDKSFVDGLNGTPQQEAIAIALTGIAETMGLRTVAEGVETPEQAQRLFELGYRHAQGFHFARPLPPEEIDALLDRAHRLAA
>NC_017093.1|WP_083888815.1|4139330_4139966_-|class-I-SAM-dependent-methyltransferase
MNGYYERPAMLTLAGNVTGRRVLDAGCGSGPLSAALRERGAVVTAFDSSPAMVKLAERRLGEDATLLVADLSEPLPFDDGAFDDVIVSLVLHYLKDWTGPLAELRRVLRPGGRLLLSVKHPIAYEVVHPDGDYFALARWSEACTFDGHRVELTYWHRPLHAMTDAFTDAGFRISVISEPPMSPDTPRELLPPHLVDRTAFLSFIFFVLEAH
>NC_017093.1|WP_014444052.1|4138214_4139303_+|glutamate--cysteine-ligase
MLTVGVEEEFLLLDPDTGANAPVAEKVRAALPEQARRQSRAEVRRSMLEMVTGVCTDLRDVRDQLGSLRRAAAIAADDAGVRLTAVAATPVSEPDRSVPDDPRYHTMIDRFGPLAQDPALCGMHVHVGVDDRDLAVQVCNHLRIWLPVIQALTGNSPFFEGADTGHSSWRNVQLRRWFSVAPTPYLRDAREHDRTVDDLIATGIMIDEGMVQWYARLSPRYPTVEIRMGDVCADVDDAVLVTALVRAAVDTALGEARAGRAAPDPRDAVVSGAHWRAARDGLGGDLVDLRDGRARPAWELIGEFAALVDPSLRRSGDRQLVRDGLVRLRETGCGADRQRAVHRRTGDIRAALEAAALWTRTT
>NC_017093.1|WP_014444063.1|4150945_4151425_+|GNAT-family-N-acetyltransferase
MSLRRADQPGDLDWIVTAHGEVYESQFGWDTSFRKLVAEIVADFAATCDPSREAAWIAEADGRRAGCVMLVAGAEPGVAQLRVLLVTGAARGLGLGGKLVAECLAFAREAGYRRVTLWTVDECVSARRIYEGVGFTLTAEEPHPGFGHPLTGQTWTLDL
>NC_017093.1|WP_014444064.1|4151876_4152476_+|DivIVA-domain-containing-protein
MTGIAKQLTPADVDGAAFRRAAPGSRGYHEGEVDAFLSDVAGEMRRLAAENRALRDRLGPDDPHARLHALEAECAQAQERVRALEAELSTISEPGPGAAGVVKLAARTADDYLADVRREAADLLGKATTEADRLISDAELRASTIVADARHRHAELMAALPGKRAAALDRIDALRAEADERRESITGEVSGRLQNLIGA
>NC_017093.1|WP_014444065.1|4152552_4156164_-|alpha/beta-hydrolase
MKIGGSLLSVVLTLAIPVGVSAPASATPPTTAAAAQALPDPTARGPYGHRVIQEAKFGLATIQEPNSDGTAPTAGTAQAAEQVEIRGQLYTPDYAKRTKPSPLIVLVHGNHGSCDSGQNSAALTCAEFKHNESGYAYLAENLATWGYTTFSLSQDQLMMRQDNAKGKGMHNRRMLLAATLDAITAANRKAGLPVDEHTTIGTTLAGRLDLSRIGMMGHSRGGDAVTNFIDYNRIRTDGPRYPISGVISLAPTDYERKAPYGMPFMTILPMCDGDVSNLMGARQFERGQTINSDDPFPKIQVEHLGAIHNWYNTVWYADGGADGQANNDAACGNSAPFATNNVHPNNLRLSGAASSTDEARNYRIGNTDPLNPEVNTKISGDPERMGDQEKLGLATMAAFFRRYIGGEGAFEAYMTGELANRPGNLQVPASACPTSESGARIPCGERVNTSYYAGAGARVDVITLQPENPLTMNALGGSLSGDGFADPYRQASGTTPKPPATPQGFDWCNPEPQDFAPGQLGKTGLPAAAKQCPLPAPAALGGQNGTRENAPINHSYGPQLTLAWEPASAATLTAEIPAASRDMSGLEALALSAAVNFFDTRNPGADNRGDNTRDTTVDGTPASPAWPNEKPTSYDPASTSQNFVIALTDTDGNEATVQAGDPRWGNALHMSTGTNTPNTHIVLDQIRVPLTEFARQGVDVRSLSSLEFRFGGAGMPASGAIQMADVRFQESASGKQIQSDGTFKADGAGYGRFDHSVKASTAAATGNVWTVDDDLQQCPNAQFSSIQKAVEAAAPWDTILVCDGVYQEQSTPLNHNANPVQTGAKNGLTITKPLTIKGTGADRVTIEPVQSLGTLEGTAPYLRDGGGNVITVSRQSLGSTDTNEMFVDISGVTVTSGDVWAEAGIAYFGAAGRVADSVVGPLKTASTGSELAAHPHGWGIIKTGNIQGTGIGTVESELSVTGSVVTGYQSGGILFDGARGRDGAPENLVRSGIRYHGHVDDTVVTGTGSSTGVKFTSGVDGHVRSSRITGGATGLLLADAGPVTASGNVFTGSGQAVANDSPATPITVSKSWFGKGKPVVSGGGSVIVSKPLSSAPKSVPTSVRRVTDHKPSAEVASPSRTSTTSPGRSVDVVIRASDDFGVTSVTLVVDGKKVATSATSPYRFSWTPTAKQAGKKVSIEARVVDSSGHVTVTDDVKVSVKKR
>NC_017093.1|WP_014444066.1|4156272_4157082_+|hypothetical-protein
MRPHPRADFFVVGVAVTIFALIIFTTPDPPCSVADACDAEPVTSIAVSLVAAVAVMSFLHRWSAVAAAVACVVMWPIADRVDDVGMGWRVTLPLALLAVTVAVARLRFPPYSPSPDLVAFVASLDEDVRPALVPPAPPRAPARPVLGTLLLVAGLAGAGWTLWHQARVTAQEASASAVPAVVREHREDAVIGVDLVNGDSFYMEVLDAADYPVGSRVEVLIDDTRMRQLRTEPYDITILLLPTITAAGAGAALLTVVRQSVRGDNTDRS
>NC_017093.1|WP_083888662.1|4157059_4157986_+|DMT-family-transporter
MTTLTGPDSRVELRRWLPSYLALAAIWGTSFLFIKVGVRELHPLWLTFGRVAAGVLILLVVLAVTRDRLPRDLRLWGHLMVVALLGVVLPFTLFGYGEQRVSSVLAGIWNAATPLVALPLAVLLFRTERMSARKAAGIGVGFAGVLVVLGVWRGLGGAQFTGQLMCFGAAMCYAVAIPYQKKFIAGRAGSGVSMAAAQLIAALAQLTLVAPLLAGAPPNPADLSGQVLLCVLALGSLGTGIAFVLNFRVVRMAGVSTSTSVTYLMPVVATVVGVLVLGEHLHWNQPVGALIVLIGVAVSQGLLRPPRR
>NC_017093.1|WP_014444068.1|4157936_4158917_-|enoyl-CoA-hydratase/isomerase-family-protein
MSEPSVIVRQQKQLGRLTLNRPAAINALTAEMVTIVARTLDGWVSDDRIRTVVIDGAGERGLCAGGDIRAIHADAVSGGTASLDFWAREYRLNATIAAYPKPIVACMDGVVMGGGIGISGHASVRVVTERSRLAMPEVGIGFHPDVGGSWLLSRAPGEIGTHLALTGSAVGAGDGIAAGLADHYVPSGRLPELLEHGDVTRVAEAPPPADLDRAWIDECYAGDDVAVILDRLASHPHPAAQAAAKEIATKSPTSLVLTLRSLREAAGLPDLRAALDAELRLSAFMLRLPDLAEGIRAQIIDKDRRPRWQPATVAEAAAALGTPPHR
>NC_017093.1|WP_041831034.1|4159011_4159803_+|PrsW-family-intramembrane-metalloprotease
MRERLRRLGWVAVLAIGLALYFLVLRTLVHTQNPNLVPAVILLGACTVPAAFLTFAQARTGQWQVPATVLLVTAFFGGVVGLVVAGTLEFDALRDLGTLPMLFVALIEETAKLVVPLLVLVTILIRHKRRLPSDGLVIGVASGMGFAALETMGYAFTALVSSGGNVGALEETLLIRGLTAPAGHTAWTGLTCGALWMLASAPGVRNAVVFLLTFAGAVALHTAWDTFGTVWAYAILAVLSLGWLVLRLRGYRAFHPLPAEPAA
>NC_017093.1|WP_157434936.1|4160472_4160982_-|hypothetical-protein
MMRSRILPVVLLGACLATLAACGDDDSPSAASSAPAAPAAAGSSTGAGSAAGAGSSAAVVAPDDKALCKTLNTAATALRNGITNAQQDGGGVRAADAKKTFIAFHTTVTEALAFAPASDVTTAAKAIADELDAAAKSADPIGSAADSDFDKLGNDLTTACKAAGVTVMF
>NC_017093.1|WP_051042067.1|4161322_4162195_+|alpha/beta-hydrolase
MTDATALRRHWGNAEDVGIRAARTPDVAIQDFEIAGRVRVRLVRPAGEDGVLPVVLFTHGAGWILGEDFTYDRMTRELALQARAAVAFVDYHHSAENRFPAAVQECYAALEWLAAQAEQLGVDAGRIAVAGDSAGAAIAVAVAVAAKERSGPAITGQVLLYPMISSSYAGASAFDAVSYHRRATEHWIMRQSGMWSTGARAQVAEPVVTHPADERFTGMPPTLIVVAEADVLREQGEGYAADLRAAGVPVIVERYAGVIHDFVMVDALGDTAAVREATGHAGRYLHYALG
>NC_017093.1|WP_014444072.1|4162384_4163911_+|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha
MIIGVPRDPQPGERRVAATPVTVAQLVKLGYDVVVQSGAGAGSSFSDEAYADAGAAIGDPFAADIVFTINPPPAEQLDKLTPGATLIGMLNPRLDRELVGDLSRRPITALSMDAVPRISRAQSLDVLSSMANIAGYRAVVEAAHAFGRFFTGQVTAAGKVAPAKVLVAGAGVAGLAAIGAAGSLGAIVRATDPRPEVADQVRSLGGEYLSVEAADVEVSSTGYAKEMSDDYNERAARLYAAQAAEVDIIITTALIPGKPAPRLITAAMVASMKPGSVIVDMAAANGGNVEGTVAGEVVVTAGGVTIIGYTDLPGRLPAQASQLYGTNLVNLMKLMTPEKDGRLVVDFEDVVQRSMTVVRDGELTWPPPAVSVSAAPAPSAVAVASPSVAAPVAPSSRNPLPLVGVAAVALFLITALAPAALRGHLTVFALAIVIGYYVIGHVHHALHTPLMSVTNAISGIIVVGALLQIGHGDAVVTALAFVATLLASINIFGGFAVTRRMLAMFSRS

Crispr_ID: NC_017093_15

• CRISPR_ID: NC_017093_15
• CRISPR_location: 4351787-4351846
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_15

Consensus_repeat	Method
CCGCCTGCCCGGTGGTGGCCGGC	CRISPRCasFinder

spacers of NC_017093_15

>15.1|4351810|14|NC_017093|CRISPRCasFinder
TCATGGGCGTCCGC

CRISPR arrays and Neighbor proteins around NC_017093_15

CRISPR arrays

The CRISPR arrays of NC_017093_15

>merge|NC_017093|15|4351787-4351846|CRISPRCasFinder
CCGCCTGCCCGGTGGTGGCCGGCTCATGGGCGTCCGCTCACCGCCCCCGTGGCGGCCGCC

>NC_017093|15|15|4351787-4351846|CRISPRCasFinder
CCGCCTGCCCGGTGGTGGCCGGC	TCATGGGCGTCCGC
TCACCGCCCCCGTGGCGGCCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_051042515.1|4353861_4355499_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|223562
NC_017093.1|WP_014444255.1|4360869_4361601_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|224584
NC_017093.1|WP_014444250.1|4356671_4357517_+|DUF3626-domain-containing-protein	unknown	unknown	gnl|CDD|372019
NC_017093.1|WP_041831069.1|4357498_4357888_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014444249.1|4355595_4356432_+|undecaprenyl-diphosphate-phosphatase	unknown	unknown	gnl|CDD|237134
NC_017093.1|WP_014444253.1|4358394_4358892_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014444256.1|4361812_4362202_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014444240.1|4346631_4347156_-|2'-5'-RNA-ligase-family-protein	unknown	unknown	gnl|CDD|379265
NC_017093.1|WP_014444238.1|4344742_4345450_+|hypothetical-protein	unknown	unknown	gnl|CDD|223616
NC_017093.1|WP_014444236.1|4343515_4344364_+|sugar-nucleotide-binding-protein	unknown	unknown	gnl|CDD|187564
NC_017093.1|WP_014444247.1|4353138_4353633_-|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|163261
NC_017093.1|WP_014444245.1|4350766_4351630_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274153
NC_017093.1|WP_014444243.1|4348924_4350043_+|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NC_017093.1|WP_041829932.1|4344353_4344704_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014444241.1|4347247_4348132_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_017093.1|WP_014444242.1|4348128_4348902_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|366444
NC_017093.1|WP_014444239.1|4345562_4346597_+|putative-GDSL-like-lipase/acylhydrolase	unknown	unknown	gnl|CDD|238871
NC_017093.1|WP_014444254.1|4359153_4359897_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014444244.1|4350039_4350651_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_017093.1|WP_014444246.1|4352035_4353142_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_014444255.1|4360869_4361601_+|GNAT-family-N-acetyltransferase	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	7.43539e-13
NC_017093.1|WP_014444250.1|4356671_4357517_+|DUF3626-domain-containing-protein	gnl|CDD|372019	pfam12294, DUF3626, Protein of unknown function (DUF3626). This family of proteins is found in bacteria. Proteins in this family are typically between 294 and 374 amino acids in length.	2.74849e-96
NC_017093.1|WP_014444249.1|4355595_4356432_+|undecaprenyl-diphosphate-phosphatase	gnl|CDD|237134	PRK12554, PRK12554, undecaprenyl pyrophosphate phosphatase; Reviewed.	1.72619e-103
NC_017093.1|WP_051042515.1|4353861_4355499_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl|CDD|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	7.77093e-128
NC_017093.1|WP_014444238.1|4344742_4345450_+|hypothetical-protein	gnl|CDD|223616	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].	8.81158e-15
NC_017093.1|WP_014444240.1|4346631_4347156_-|2'-5'-RNA-ligase-family-protein	gnl|CDD|379265	pfam13563, 2_5_RNA_ligase2, 2'-5' RNA ligase superfamily. This family contains proteins related to pfam02834. These proteins are likely to be enzymes, but they may not share the RNA ligase activity.	2.53914e-18
NC_017093.1|WP_014444236.1|4343515_4344364_+|sugar-nucleotide-binding-protein	gnl|CDD|187564	cd05254, dTDP_HR_like_SDR_e, dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs. dTDP-6-deoxy-L-lyxo-4-hexulose reductase, an extended SDR, synthesizes dTDP-L-rhamnose from alpha-D-glucose-1-phosphate, providing the precursor of L-rhamnose, an essential cell wall component of many pathogenic bacteria. This subgroup has the characteristic active site tetrad and NADP-binding motif. This subgroup also contains human MAT2B, the regulatory subunit of methionine adenosyltransferase (MAT); MAT catalyzes S-adenosylmethionine synthesis. The human gene encoding MAT2B encodes two major splicing variants which are induced in human cell liver cancer and regulate HuR, an mRNA-binding protein which stabilizes the mRNA of several cyclins, to affect cell proliferation. Both MAT2B variants include this extended SDR domain. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.23526e-54
NC_017093.1|WP_014444247.1|4353138_4353633_-|PadR-family-transcriptional-regulator	gnl|CDD|163261	TIGR03433, padR_acidobact, transcriptional regulator, Acidobacterial, PadR-family. Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions].	3.60049e-18
NC_017093.1|WP_014444245.1|4350766_4351630_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274153	TIGR02479, RNA_polymerase_sigma_factor_WhiG, RNA polymerase sigma factor, FliA/WhiG family. Most members of this family are the flagellar operon sigma factor FliA, controlling transcription of bacterial flagellar genes by RNA polymerase. An exception is the sigma factor WhiG in the genus Streptomyces, involved in the production of sporulating aerial mycelium.	4.52729e-52
NC_017093.1|WP_014444243.1|4348924_4350043_+|two-component-sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.9339e-36
NC_017093.1|WP_014444241.1|4347247_4348132_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.34416e-80
NC_017093.1|WP_014444242.1|4348128_4348902_+|ABC-transporter-permease	gnl|CDD|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	4.26473e-09
NC_017093.1|WP_014444244.1|4350039_4350651_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	7.76003e-59
NC_017093.1|WP_014444239.1|4345562_4346597_+|putative-GDSL-like-lipase/acylhydrolase	gnl|CDD|238871	cd01833, XynB_like, SGNH_hydrolase subfamily, similar to Ruminococcus flavefaciens XynB. Most likely a secreted hydrolase with xylanase activity. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	6.63598e-51

Protein sequences

>NC_017093.1|WP_014444245.1|4350766_4351630_+|sigma-70-family-RNA-polymerase-sigma-factor
MTATVQITVTREQEDLIRDNMALVGHMVREMLFKVPPHVHRDDLASAGYAALVTAAQSFDAERGIPFGRFAAVRVRGALLDELRSMDWASRSVRARARRADVAREELTRQLGRTPTAEELAELLGVAVGELSSVDDDVQRAAVLSLQGFATGTAEDLVTETAMNPEELLLHRERLGYLHDAVTVLPERLRYVVEASFLQERPLSEVAAELGVTESRVSQLRTEALALLRDGLTTHMEQKRVPDAKDGCVARRRAAYAAQIAARSTMTTRLGATDAQGLRLSDMPAAA
>NC_017093.1|WP_014444244.1|4350039_4350651_+|response-regulator-transcription-factor
MIRLLLADDQALVRGAMAALLDLEPDLTVVAEVGRGDEVAAAAADHRADVALLDVQMPGLDGISAARVLHERVPSCRVLMVTTFGRAGYLKQAMAAGADGFIVKDTPARQLADAVRRVHQGLRVVDPALAAQSLAHGDSPLTERESDVLRAARDGGTVADIARELRLSEGTVRNHLSSAIGKTGARTRAEAVRLAVEVGWLIP
>NC_017093.1|WP_014444243.1|4348924_4350043_+|two-component-sensor-histidine-kinase
MVDERPAPKYGWVFAAVWLFYLGENLTALLRADPGWQRSVGLAALAGFAVVYVLVLAQVRHFRGLTAGAVTATSREQLIIGTALVLMTGLGALQVPGAGPHALTCLVYVAATAMMGLPRRQGITVAVTLVILAEVLLRTMPGWKTAGHGYSLAIVLAAVATGGIRLALDRQRRLREAQHEIAELAVADERARIAADLHDILGHSLTVVTLKAELAQRLLDVDLDRARTELRDLESLARDALADVRATALGMRGISLPGEIAAARQALAAANVEADLPGAADDVPTRNRELFAWTIREAVTNIVRHSAARHAAVRLSPGQVEIVDDGTGVTGPDRGGQGLAGLRRRAGEAGARLTAGNRDDEPGFRVLMEVPE
>NC_017093.1|WP_014444242.1|4348128_4348902_+|ABC-transporter-permease
MTVLDRTLPRFGGFSLGMIGLELRRMLRNKRTIIFTLVMPAAFFLLFGSSAEYRTERVGDGNVTGYVLVSMAVYGAMLATTSGGAMVSIERAAGWSRQLRLTPLKPLAYVAVKLLLAMIIGAVSVAVAFAVGAVGGAELPLRAWIGCGLLAWLCSLVFAAFGLFMGYLLPSENVMQILGPALAVLSFAGGLFVPVDQLGSTFATIATFTPVYGVGEIARYPLVQDGDLWVAALNVIVWTALFSAGAMWRFRRDTARV
>NC_017093.1|WP_014444241.1|4347247_4348132_+|ABC-transporter-ATP-binding-protein
MKAVELEGVVKRFGTVTAVAGLDLRIRPGEVVALLGPNGAGKTTTIDMLLGLTRPDAGTVRVYGHAPQDAVALGLISAVMQTGGLLKDYTVGETVRLTAVLFGKPRAAVDKVLERAGISDIADRLVGKCSGGQQQRLRFAMALLPDPELLILDEPTTGMDVGGRHDFWTAIRQDASGGRTVVFATHYLEEADAYADRVVFVRRGRIVADGTASEVKALASGRTVRATLPGASTGDLTAIPGVESAEVRGDSVYLHGRDTDTIARHLLTATPARDLEITSRNLEEAFLTLTADAS
>NC_017093.1|WP_014444240.1|4346631_4347156_-|2'-5'-RNA-ligase-family-protein
MEPTQSALIVSVPEAEPAVAGLRDRLDSFAAQGVPAHVTVLSPFLPPAQLTPQVLAAVQLVAAGVPGFFVSFDRVAWFGDRVLWLAPDPAEPFRELTNRIAARFPAAQPYGEQFAEVVPHLTIGHGRPVAALRAAAAEVEPLLPIRARVTALRLLAGAPEAGEPWHTLADFPLG
>NC_017093.1|WP_014444239.1|4345562_4346597_+|putative-GDSL-like-lipase/acylhydrolase
MLRSLLPALALAAGVLSGTPAMASGDAPMRIMPLGDSITAGVGVPGKDGYRLALQRALERAGERVDYVGSQKGGTDGDIDHEGHGGWTIDQLAEQTTGWVTTYRPDVVLLHAGTNNITLGEEPSAVAGKLSALIDQVRAAAPAARVYVATIVGTTVASEVAANRAYNALIPGVVAGKGALVRLVDQSAVDGLSIYDRHHPNAYGYARMAYAWYEGLRATIGPAWRIAADPDDTAFAYLCHYYTVRDCRWWQRRPVTTTVDGATVTRVQWQTRRYVPKIVEETVPGHYETVTKRVWVKGHHETRTVKKGTSKVWVKGRYVDRLVRTWVPATTVSTTRPVPTWVSS
>NC_017093.1|WP_014444238.1|4344742_4345450_+|hypothetical-protein
MTSPVRLDDLIQAINKTSPDSPIDRLSDAVLVADHLGELADHLIGHFVDQARRSGASWTEIGAGLGVSKQAAQKRFVGKLDPSQGFHRYSDAARSAVVGSMSQAKALGHPEIAPGHLMLALLDVPDGLAARALTAQGLDRDAVRSGATASLPAPAGDVPALIPFDAHAKKALELSFREALRLEHDLVGTGHMLLALLEEEEPEGGVLGRLGIHKAAVERTVLAGPQESGSAQQPG
>NC_017093.1|WP_041829932.1|4344353_4344704_+|hypothetical-protein
MTDKRSIRVTVRGSFDNLTADQKAELLAAGPDHADILAVQYTEQGHLTYDLAARPFFTFRFGAQVTDEKDIPKVTAQAEAKAAAWMTERGYGFKRITSQTVDMSEVPLGPRGRRQQ
>NC_017093.1|WP_014444236.1|4343515_4344364_+|sugar-nucleotide-binding-protein
MRILITGGTGSLGRRVVARAAAAGAEPVGTYLSAPPSAIGPATASVRLDVRDQADVRRVLREVRPDAVVHAAAGRDRNDWPANADGAANVAVAAADCGVRLVHVSSDAIFSGRAVHYAEDAVPDPVYAYGAAKAAAETAVRAAVPSAAVVRTSLILGDGNGYHEKLTHDLVAGRVTGALFTDEIRTPVHVDDLADALLELAAGDYAGVLNVAGADPVSRYELGVLVARRDGLDVSRIPATTTAEMGLQRPADVRLVIDRAAEVLKIRLRGAHEFVDTGARDR
>NC_017093.1|WP_014444246.1|4352035_4353142_-|hypothetical-protein
MTTSDWPQADPGLERAYHRLLRAYPRDYRRRHGAEVVTTLLEMAAPGQRRPDRADARHLIVSGLRHRFRLPAGRPLAWVAAVLVTLIGGAFGAAAGSWAVEQAVLPAPDGQAAAALHRTVVGAGGTGTTAVEWDPVSSPWGTDAVGWSTSIAAWDADAARHRLAADGWALSEATPARGITDMISDGSGEVLQRSVAGWEFTADRDGVRLDVTARLIGSDGYSPADGGVTTTVAAAGSAALVPAIAAGGVFGLVAGWLVAAATARRVRRLPAGRARVVTTLSTAAVLVLALPVVALYGNVIRAVESAGIPGHVRTVHSAFKLGPYWPFGPFWLNLALLATGLALGVAAVALTATRHPAVPAASTQPQPS
>NC_017093.1|WP_014444247.1|4353138_4353633_-|PadR-family-transcriptional-regulator
MQEPTFLILTALAGQPLHGYGIVRSVLDLSGGEVKLRAGTLYGALDRLADQGLIEVEREEAVEGRLRRYYRLSDDGAATLAAEVERLRKRASAAETQLRRRPGIVPGLSRGASLGSAFRGSAFRGSAFGGNAFGGNAFGGNAFGGNALRGSALRGDDAVLGGLA
>NC_017093.1|WP_051042515.1|4353861_4355499_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MQHKSTQQKSGQGNSGSAHLKAAGLAATHDGDLLFSGLDLVLRAGDRIGVVGPNGAGKTTLLRVLAGELPASAGAVSVAPGARLTHVPQQWAGDAESVGAFLRGGLGELAAVDLALRALEARLAAGADVLDEFGTVQERWTALEGWNADARLTEIRQRLDIEHLADDLAMSQVSGGEQARLLLARALLGSPDLLLLDEPTNHLDAEGAAWLRTWLRDFDGGVLAVSHDRAFLDEFATRIIELDGIDEQPQDYPGCGYTAYRAEKQRRWEKLLLDFEAQEKDRLRWEADIEKTKGYARGVESSVRSGVTAPHLRRVARLVARKAKVRERRLRRQMASVTWLAQPRTRPPLTLAFPGDDTADAEIVLKARGLTVAHGDRVLLDAVDLDVTRGDRILITGRNGAGKTTLLRALESPDVAVLPQTDEGLRTATPVIDFFRSRVPVYVDDAERLLAGHQFEDSQWSAPVRDLSAGELRRLLLAVVVNSPSRILLLDEPTNFLDFEALDVVEEALRRYRGTLLFASHDRYFADAVGHTRHWHVEGGRVIEN
>NC_017093.1|WP_014444249.1|4355595_4356432_+|undecaprenyl-diphosphate-phosphatase
MSIVEAVILGAVEGVTEFLPVSSTGHLTILEKLFGHTIDDPDITAFTVIIQSGAVLATILFLRKDIARVVPAFFRGLFNKAYRDHPDFRFGWAVLLGSIPIVIAALLFKDAIETTLRSLWFVAGALILWSGVMAFADHAATQVRGEKDVTWKDTLIIGTVQCMALIPGISRSGATMSAGLLRDLDRVTVTKLSFFLSIPALTGASILQGVGEADRISSGVGWTNTIVATVVSFVVAYASVTWLLKFVSKHSYSIFIFYRLALGSLLLLLLATGTISAK
>NC_017093.1|WP_014444250.1|4356671_4357517_+|DUF3626-domain-containing-protein
MPRRRQFETRISNGGLLAYPGGDRDRWEHDMFGGAYTGVIGRPIYGALNLAGHPDGAAPRFGSCHLVLAAGVPARSTFCHGDSHLGPAAVGTADAFGAIRAALIDEVARTGQALGVPAPTVGSPPGWETVLAARRAALQHSLDDPSRHPLRGHAPGRTLDDYVEAQIHGGLTLSDDVTAIVADPSFQGTPTEAHLASLGIPLHWHAGFTLAAADVPADLRGPEVPPLARRIATRHRRPDLDAELIGRAARAAATDPHRLQLIKYLWHLLVLLGRPAHQSRH
>NC_017093.1|WP_041831069.1|4357498_4357888_-|hypothetical-protein
MRERPTAVWRRAVEEQRAEVAAGTLAAEEAYADELWPAGFIAAVDAVLEAYEQEVAGWRSPSDEQIWAAVERVVVGLNEADGGHIETGEREDLAGYVDVVLTRTGVDVVALTGRRGRHRSELTDQWRDW
>NC_017093.1|WP_014444253.1|4358394_4358892_+|hypothetical-protein
MLIEGNDGVTVSLRPARWQFPADAGAWDDRWLVIDGTVNLGDKAWSFTDPCLLIEEAHELAIWLRNAAQDRIASSQTAAGEQVEPSLSFMEPLLGFSVTAHRDDELVLHVELAAEAAPPWLHVANPHSDQYTVELRLRSDELLAAATAWSQQLDALPSRTFARTD
>NC_017093.1|WP_014444254.1|4359153_4359897_+|hypothetical-protein
MANLVHLTPEDRARRIVRSGVAARSSGGAGERGVYCMPVLTSYMLTHQWVRELRRWHPGVLAAVDLRISDDEPVQVGRYNREPERCPAARAVALVREAADPRGFEIFVPRAISAGEVRGVRSVAQSIGWRHKPDAHGVRPCPCPACIQPGTPKVARLRRRLPGEDFRPRRTKPELMAQLRGAATAEDVCDALWGLGARSRGGAEELEFLADHPDPDLRELLYEVLESYRGKAARELRARLLSKADWL
>NC_017093.1|WP_014444255.1|4360869_4361601_+|GNAT-family-N-acetyltransferase
MSDLGPVVPWPPEPIRTERLVLRASEARDRAGFVELFASAEVHTYLGGPRSRGELERELPTVPEQWPGSFVVELTPPISDRAASDQPMGDRATIDQPMGGRAASDRAVIGRATSDHCLAGQPGPGQRTADSAMIGQVLLRRATAHRRPAAAGRADLGYLFLPWVWGRGYAAEACTAVLAWFDAVLPGEPVVLTTQSANVASMRLAARLGFTEVERFHAWDAEQWLGLRPSTAVPRYPATRPRP
>NC_017093.1|WP_014444256.1|4361812_4362202_+|hypothetical-protein
MNLRLALLLGLVGLGRPVLSIIGAYDGGPLAKPVGPLLMTALISLVWVAAAVWLKVRNPVLTLAVAGIAYAVFAILLNWSLQPFLASAETIPLPGHLAMLLFNAAQGAILGLIALGIQRLIARRRRAVR

Crispr_ID: NC_017093_16

• CRISPR_ID: NC_017093_16
• CRISPR_location: 4496493-4496579
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_16

Consensus_repeat	Method
TGGCCGTCATGACCCCGCCGGTGCG	CRISPRCasFinder

spacers of NC_017093_16

>16.1|4496518|37|NC_017093|CRISPRCasFinder
CGTGAGCTCGCTCGTGTTGTCGGCTGCGGCGTGGGCG

CRISPR arrays and Neighbor proteins around NC_017093_16

CRISPR arrays

The CRISPR arrays of NC_017093_16

>merge|NC_017093|16|4496493-4496579|CRISPRCasFinder
TGGCCGTCATGACCCCGCCGGTGCGCGTGAGCTCGCTCGTGTTGTCGGCTGCGGCGTGGGCGTGGCCGTCATGACGCCGCCGGTGCG

>NC_017093|16|16|4496493-4496579|CRISPRCasFinder
TGGCCGTCATGACCCCGCCGGTGCG	CGTGAGCTCGCTCGTGTTGTCGGCTGCGGCGTGGGCG
TGGCCGTCATGACGCCGCCGGTGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_014444393.1|4484056_4484905_+|LLM-class-F420-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274681
NC_017093.1|WP_014444409.1|4502944_4504141_-|homogentisate-1,2-dioxygenase	unknown	unknown	gnl|CDD|226039
NC_017093.1|WP_014444395.1|4486459_4489609_-|glycosyl-hydrolase-115-family-protein	unknown	unknown	gnl|CDD|379757
NC_017093.1|WP_014444396.1|4489753_4490482_-|trypsin-like-serine-protease	unknown	unknown	gnl|CDD|214473
NC_017093.1|WP_014444399.1|4492689_4493079_+|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|378915
NC_017093.1|WP_014444401.1|4493938_4494778_-|patatin-like-phospholipase-family-protein	unknown	unknown	gnl|CDD|366777
NC_017093.1|WP_014444408.1|4502075_4502948_-|hypothetical-protein	unknown	unknown	gnl|CDD|235906
NC_017093.1|WP_063711169.1|4506210_4507206_-|trypsin-like-serine-protease	unknown	unknown	gnl|CDD|214473
NC_017093.1|WP_014444406.1|4499988_4500624_-|5,6-dimethylbenzimidazole-synthase	unknown	unknown	gnl|CDD|380321
NC_017093.1|WP_157434961.1|4507252_4507393_+|hypothetical-protein	unknown	unknown	gnl|CDD|197715
NC_017093.1|WP_014444398.1|4490801_4492547_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014444411.1|4505714_4505945_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014444394.1|4485235_4486456_-|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238868
NC_017093.1|WP_014444410.1|4504143_4505337_-|4-hydroxyphenylpyruvate-dioxygenase	unknown	unknown	gnl|CDD|273528
NC_017093.1|WP_083888673.1|4497326_4499855_-|glycoside-hydrolase-family-127-protein	unknown	unknown	gnl|CDD|369609
NC_017093.1|WP_083888674.1|4500909_4502142_-|fumarylacetoacetase	unknown	unknown	gnl|CDD|215461
NC_017093.1|WP_157435380.1|4483313_4483907_+|ATP-dependent-endonuclease	unknown	unknown	gnl|CDD|173776
NC_017093.1|WP_014444412.1|4506004_4506205_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_041831101.1|4494812_4495217_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014444391.1|4482855_4483140_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_083888673.1|4497326_4499855_-|glycoside-hydrolase-family-127-protein	gnl|CDD|369609	pfam07944, Glyco_hydro_127, Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context.	9.4847e-166
NC_017093.1|WP_014444395.1|4486459_4489609_-|glycosyl-hydrolase-115-family-protein	gnl|CDD|379757	pfam15979, Glyco_hydro_115, Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.	5.26222e-175
NC_017093.1|WP_014444396.1|4489753_4490482_-|trypsin-like-serine-protease	gnl|CDD|214473	smart00020, Tryp_SPc, Trypsin-like serine protease. Many of these are synthesised as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. A few, however, are active as single chain molecules, and others are inactive due to substitutions of the catalytic triad residues.	6.89285e-27
NC_017093.1|WP_014444399.1|4492689_4493079_+|nuclear-transport-factor-2-family-protein	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	2.81395e-07
NC_017093.1|WP_014444401.1|4493938_4494778_-|patatin-like-phospholipase-family-protein	gnl|CDD|366777	pfam01734, Patatin, Patatin-like phospholipase. This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have been found also in vertebrates.	3.61057e-19
NC_017093.1|WP_014444408.1|4502075_4502948_-|hypothetical-protein	gnl|CDD|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	0.000330681
NC_017093.1|WP_063711169.1|4506210_4507206_-|trypsin-like-serine-protease	gnl|CDD|214473	smart00020, Tryp_SPc, Trypsin-like serine protease. Many of these are synthesised as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. A few, however, are active as single chain molecules, and others are inactive due to substitutions of the catalytic triad residues.	5.2117e-27
NC_017093.1|WP_014444406.1|4499988_4500624_-|5,6-dimethylbenzimidazole-synthase	gnl|CDD|380321	cd02145, BluB, 5,6-dimethylbenzimidazole synthase. BluB catalyzes the O2-dependent conversion of FMNH2 to 5,6-dimethylbenzimidazole (DMB), a component of vitamin B12; is is a subfamily of the nitroreductase family; nitroreductases typically reduce their substrates by using NAD(P)H as electron donor and often use FMN as a cofactor.	1.81669e-68
NC_017093.1|WP_157434961.1|4507252_4507393_+|hypothetical-protein	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	0.00681214
NC_017093.1|WP_014444393.1|4484056_4484905_+|LLM-class-F420-dependent-oxidoreductase	gnl|CDD|274681	TIGR03620, F420_MSMEG_4141, probable F420-dependent oxidoreductase, MSMEG_4141 family. Members of this protein family, related to F420-dependent oxidoreductases within the larger family of a bacterial luciferase (an FMN-dependent enzyme), occurs only within the small subset of species that synthesize F420. Most such proteins are from members of the Actinobacteria, but at least one species, Sphingomonas wittichii, belongs to the Alphaproteobacteria. [Unknown function, Enzymes of unknown specificity].	7.49057e-109
NC_017093.1|WP_014444394.1|4485235_4486456_-|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238868	cd01830, XynE_like, SGNH_hydrolase subfamily, similar to the putative arylesterase/acylhydrolase from the rumen anaerobe Prevotella bryantii XynE. The P. bryantii XynE gene is located in a xylanase gene cluster. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	2.47253e-86
NC_017093.1|WP_014444410.1|4504143_4505337_-|4-hydroxyphenylpyruvate-dioxygenase	gnl|CDD|273528	TIGR01263, 4-hydroxyphenylpyruvate_dioxygenase, 4-hydroxyphenylpyruvate dioxygenase. This protein oxidizes 4-hydroxyphenylpyruvate, a tyrosine and phenylalanine catabolite, to homogentisate. Homogentisate can undergo a further non-enzymatic oxidation and polymerization into brown pigments that protect some bacterial species from light. A similar process occurs spontaneously in blood and is hemolytic (see . In some bacterial species, this enzyme has been studied as a hemolysin. [Energy metabolism, Amino acids and amines].	4.15647e-158
NC_017093.1|WP_014444409.1|4502944_4504141_-|homogentisate-1,2-dioxygenase	gnl|CDD|226039	COG3508, HmgA, Homogentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism].	3.8516e-61
NC_017093.1|WP_157435380.1|4483313_4483907_+|ATP-dependent-endonuclease	gnl|CDD|173776	cd01026, TOPRIM_OLD, TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family. The bacteriophage P2 OLD protein, which has DNase as well as RNase activity, consists of an N-terminal ABC-type ATPase domain and a C-terminal Toprim domain; the nuclease activity of OLD is stimulated by ATP, though the ATPase activity is not DNA-dependent. Functional details on OLD are scant and further experimentation is required to define the relationship between the ATPase and Toprim nuclease domains. The TOPRIM domain has two conserved motifs, one of which centers at a conserved glutamate and the other one at two conserved aspartates (DxD). The conserved glutamate may act as a general acid in strand cleavage by nucleases. The DXD motif may co-ordinate Mg2+, a cofactor required for full catalytic function.	1.57943e-08
NC_017093.1|WP_083888674.1|4500909_4502142_-|fumarylacetoacetase	gnl|CDD|215461	PLN02856, PLN02856, fumarylacetoacetase.	2.097e-141

Protein sequences

>NC_017093.1|WP_041831101.1|4494812_4495217_-|hypothetical-protein
MTTTQTHKPSLVRRISRPLTIAAGAAGALLLWAVNDPRGGHDLIVDRGVIGPVAVLATALLAGLAAWALLAILERRTRRPARTFRIIAAIVLLLSLAGPLGAGGDLTTTLALIGLHLTVGLALIIGLPARRNCR
>NC_017093.1|WP_014444401.1|4493938_4494778_-|patatin-like-phospholipase-family-protein
MTKALVLGGGGVTGIAWHLGLLCGLQRAGVPLGGADTIVGTSAGSVVGTLLAAGVDLEAAVAEQLREVAPRPGGGGGGGRGTGQFLAALAVLADPSVPPQQARAQVGAMALTAPTADEATYLSRMEPLIPVRDWPERDLRLVVVDAADGRDLVLDRASGATLLQAVSASCAVPGLMPPVTIGDARYMDGGVRLGAGADLAAGADHLVVIAPMAALSRDRIRAEMASTGAGKTLLVEPDEAALEAFGPNFMDPSRRPAAAGAGLRQGEALAEAVRAVWPA
>NC_017093.1|WP_014444399.1|4492689_4493079_+|nuclear-transport-factor-2-family-protein
MHPFRSAVEARDAAAVEALLADDVVFVSPVAFPPYPGKAITAAILRGALRVFEDFRYVREIAGERDHALVFEATVGGKQVTGCDFLHLDEDGLIDEVMVMVRPLSGANALAEAMGAQFDQIRREAAAQA
>NC_017093.1|WP_014444398.1|4490801_4492547_-|hypothetical-protein
MGTADDLRLLRAYEPVAKFTEGEYFYPISVERFVRQAGLWRAEPGAHPVQILEPGGLTLDTLAEAGGAQHGLGYSISGIGSERLTHIPLRERPPHLARASRLASVGLTARLVDTLNRFSLLFRGSVPGGSAAHSFLLQRDHLEPMRPMYYGRVLRDDPWIVLQYWYFYSFNNWRSAFGGVNEHEGDWEQVTVFLDGTGDPAEPRPAWVVFSAHDETGDDLRRRWDDPDLTLVGGTHPVVFVGAGSHSGAYLPGDYLITVRPPRLRGLVTALRWSARLLAPWSPEDQRTVGIPYVDYARGDGRAIGPGQREAWHPVVISDETPWVRDFRGLWGRDTRDRLGGERGPAGPRYTRDGTVRACWADPVSWAGLAKVIPDPSEERRYAEIRTQKDRDRLAELDQEIAALRHELAVAAAGLPAADPEVRALAGQEQRLLSLRMEHTRLADELHRATLTPGPVPDDPHAHLQHRRLPMEQATGLLGRSRSWWAVLSTPLILWAIGAVASPLAAIQGQETALVLLLLLLGVEGLVRGKFFAVLLRLLVAAAVIFLISVLVVDGRYVITFGFFAAALLVLLVNIREAWRR
>NC_017093.1|WP_014444396.1|4489753_4490482_-|trypsin-like-serine-protease
MFRNVVRVAVGLAVAAAAALFVASPAQAVLGGKLATSAPWAVRIYADGQPICTGAVVAPRWVITAAHCVQFDNTKITFRVGNLDQRRGKVVKRIPGRTYFASNADVALVQIPLVTVKPIALPVKTQKPLRVGSVLTVQGWGATCEPNEAKCQSNRLRQATVTVIKHSRNQCYMLAGTSDYCATKKSGLPVGGDSGGPALTRTKRGTAVLQGVLTDSDRRSTVAVAAATKLRPWIVKTINTKR
>NC_017093.1|WP_014444395.1|4486459_4489609_-|glycosyl-hydrolase-115-family-protein
MRNRPLILLTALALAVTAAPSVASAQAPIPTSASAHPTAGARGGGSYISTTPGPGRFPLVAAGRAAPIIVDSGDFPGVVRVAGDLHTDLRSATGVSADLRAVAFGVDGEARSAGAGAGAGAGAGAGAGVGVGVGAGATAEVGADAAASLAGGRDPVILGTLGRSALVDRLAAAGKIDTRGIAGKWETSLQQVVENPLPGVRRAFVIAGSDQRGTIFGVYDVSKRIGVSPWHFWDDVPVPHADALYALPGRHTQGTPKVKYRGFFINDENPATGTWAPNYFGPGKAPGYSGGLNAGYYAKVFETMLRLKANYLWPAVWGRAFAEDDPANHETASRYGVVMGTSHEAPMMRGIEEWNRHAKAAVRDANGTIVTPGSDPYGGTGEWSFRRNRDAIVAYWRDGARRMKEQGFEGVITLGMRGNGDVSLPDGDGIDLMSSIIETQRGILAEFGLEEAPQVQTLYKEVQRYWDKGYQPPQDVTVVFCDDNWGNMRKLPHAGLPPRGGGYGLYYHFDYVGDGRNYKWVDTTNLVNTWEQLHLSYSKGVDRLWVVNVGDLKNEEMPTQFFLDYAWNPDALPVSELGAWERKYAAENFGPELAPRIAEVLSEYGRLQSRRKPELLNRRITGDAANVVYNDQENPYTPEEMDAVVAEWQALAAEATRIKRRIPAAARDAYFQLVDYQVQAGANLYELRRAQFTNIRYAAQGRAATNDLAAEAEARFAEDQALSEHYNTRLAGGKWAGWQTQPKIGYGNAARYNNASWQQPQTDDHVALPDEIYPHLKRIEVPAAASMGVESLLPELSPWQSGARRYIEIYNKGTTAFDYRITTGQPWLRVTPSAGRVDEQVRVAVTVDWRKAPGGLTTVPITIEGPGGTQVVQAAVRNPALRPAGFAEAGGYVAINADRYDRRVGDWQLLPDIGKVGNGMAAVTGNGRLEYRMTLTTTGPVKISAHLSPRNNVLPGTGLKYAISVDDQPPQTVDVIAATGADDTTMNRQWARNTSDNVNVTTTTHVIDRPGTHTLTFHAVDPTVILQRLVVDTGGVGYSYLGPAESRRF
>NC_017093.1|WP_014444394.1|4485235_4486456_-|SGNH/GDSL-hydrolase-family-protein
MRRRTLLASSGFAASGLLLTRGRDQLSRWTHTWTAMPQLTEPHNMPPAPFDRLADTTLRQTVRVTAGGRRLRVRYSNAFGTADLPITAAAVALPVGNQAGMSAIRPGSSRPLTFGGSPSVVVPVGAQIVSDPVDLPVLAAANLTLTTYLRDGIATAELTSHPGSRTTSWLVKGDQHTALDLAGATGSDHWYLISGVEVLAGASGLVLLGDSLTDGRGSTTNGNNRWPDQLFDRLRDPELAVLNQAAGGNRVLRDGLGPNALARLDRDVLSTSGARWLLVFEGVNDIGVAPATVADQQRITAELIGAYRQIMLRAQAAGLRAYGATLTPFGGNIYDDAEGLRERSRQAVNAAIRGGLFDAVVDFDAAVRDPAAPARLAGPYDTGDHLHLNPTGYGALAAAVPRRLLR
>NC_017093.1|WP_014444393.1|4484056_4484905_+|LLM-class-F420-dependent-oxidoreductase
MSWSERLGGVGVWRPGPFLDRDLATAIEDLGFGTLWLGGSPGSDLRQAEELLDATTSLQLATGIVNIWASDAAELADSYHRIEARHPGRLLLGIGSGHREANPERVRPVDAMARYLDVLDAREVPVQSRVLSALGPRMLAMASERSAGTHPYLTVPSQSGEARAALGPDALVAPEQTVVLDTDVESARRSARRFLRLYLGLSNYTTTMRRAGFTDDDVAGEGSDALVDRLVVHGDAAVIAAAVREHHDAGADHVCVQVQPQRDDIVPALRALAAELKLRPQG
>NC_017093.1|WP_157435380.1|4483313_4483907_+|ATP-dependent-endonuclease
MARAQSAASVILVEGLTDQIALETAAALCGRDLDAEQVVIVPIGGAHAISRTLSVLITPSSRPALPAAKTRLAGLCDVQEEQIFRRGLEAAGLGSPRTRAEMEQLGFHVCIDDLEDELIRAVGVSGVTALFMSQRDLRSFHSFQKQPAWRGQDTRAQMHRFVRSSSRRNLRYARLLVEAAVAGNALPRPLDAVLNAV
>NC_017093.1|WP_014444391.1|4482855_4483140_-|hypothetical-protein
MGAGSWVILDVGAFAATALTVAAWLFGMQGVEVASWFAAVSGVLVVLGTILFTQNTVPLEDPLQVTPPPGGPKWGAITPADPERPVSAPPAPAH
>NC_017093.1|WP_083888673.1|4497326_4499855_-|glycoside-hydrolase-family-127-protein
MIPLIGPEQRSCGKACASTRPKSSASCRGIEPVQRSSYVDVNVHPPRYEYIGRLRSLPSPSSGGFVSSLPLSRRSVLRAAGAGAVVSAVGVSIAATTAEADAAVVPPVRTDIGNAASEFMPGQVRLTASRLLDNQNRTMNYLRFVDVNRMLYVFRANHRLSTAGAAANGGWDAPNFPFRSHMQGHFLTAWAQAYAYTGDTTCRDKADYMVAELAKCQANNAVAGFNAGYLSGFPESDLDAVESGKPIAVSYYCIHKTLAGLLDVWRLIGNTQAKDVLLKLAGWVDWRTGRLSYSQMQTTLQTEFGGMNEVLANLYQQTGDARWLRVAQRFDHAAIFDPLAANRDELNGKHANTNIPKWVGAIREFKATGTTRYRDIAGNAWNITVGAHTYAIGGNSQAEHFKAPNAIAGYLTNDTCEQCNTYNMLKLTRELWQLDPNRAGYFDFYENALYNHLIGAQNPADSHGHITYFTPLKAGGRRGVGPAWGGGTWSTDYNSFWCCQGTGIETNTKLMDSIYFRGGTTLTVNLYVPSTLNWSERGLTVTQTTAYPVGDTSTFTLSGSVSGSWGIRFRIPAWAAGATIAVNGANQNITVTPGSYATVTRTWADGDTITVRLPMRVIIKAANDNADIQAITYGPSVLAGNYGNTALSALPSLTVSSIARSSTTSLAFTATANGARVNLGPFWDAQGFNYTVYWNAGGSPQQPTGTVKLVNVGSNLVLGIQDMSTADGGLALQWGDTGTADHNWTMVTSGNNVKFRNANSQKVLGVENMGTGDGARVLQWGDTGTADHLWTLVNNGDGTYKIRNVHSGKLLAIQNNSTAQGALAVQDSDNGGADNRWRIVNN
>NC_017093.1|WP_014444406.1|4499988_4500624_-|5,6-dimethylbenzimidazole-synthase
MSSQLYDVIHRRRDVRGQFTGAPIPPAVLDRVLAAAHAAPSVGLSQPWDFILVSDESTRVAFHDHVQRERAAFASTLDPDAAATFSKIKIEGVRESTLSVVVTYDPDRGSPAVLGRHAIADAGLYSVCLAIQNLWLAATAEDLGVGWVSFYREPFVQDLLGIPAGIRPVAWLCLGPVTHLEETPDLERHGWRRRMPWQSAVHENRWSPREG
>NC_017093.1|WP_083888674.1|4500909_4502142_-|fumarylacetoacetase
MQHQRAGRRPAAARTSPGGHPVSPLGSPATLPYGVFSTAADPHPRAGVAIGDQIIDLPAAVRRLAPQLAGAVAGPSLDALLAAGPRVWADLRAQLTTWVTDEIHRDLIAAHLVPAREATMHLPFTVADYVDFYASEQHATNLGRILRPGQEPLTANWKHLPIGYHGRAGTVVVSGTDIVRPSGQRVGPVFGPSQRLDIEAELGFVVGVGSSLGKPVELGAFEEHVFGVCLVNDWSARDIQAFEYVPLGPFLGKSFATSISPWIVPLSALDHARVAPPERSVPVQPYLDDEKTPAWGLDVRLTVTLNGHVISQPRAADMYWTGAQMLAHLTVNGASLRTGDLFASGTISGGSPGSLIELSWNGQEPLALPDGSTRAFLEDGDEVVISAVAPGPDGSTISFGEVRGRIVSAL
>NC_017093.1|WP_014444408.1|4502075_4502948_-|hypothetical-protein
MNPLFARLFDDAAIFPPGDLPVPDAVKAYRERQLSPLEPLLGPFVCSLARLDELVAAAGPVAASAPVAAPAPIAAPAPIAAAEPIAAAAPGRPLPVSLVLPGPDVAAIPAASTAIEVVAVEGPELISPGGTLTAYREVGRGEITAARVAALRDAGLRLKIRTGGVRPDAFPTEKDLAEAICRATAGGVPFKLTAGLHDPIRHRDPLTGFEHHGFLNVLVATAHAVQGGGVDEVAAALADQDGHRVAAAIATIDDRLARDVRRQFVSFGTCSISEPVDGLLQLGLLPEDIL
>NC_017093.1|WP_014444409.1|4502944_4504141_-|homogentisate-1,2-dioxygenase
MAHYQRAGHVPPKRHTQHRDPDGRLYYEELMGEEGFSSDSSLLYHRHVPSAVVGARIWQLPDQATQSNQPLLPRHLKLHDLFEGEEWKSCDAVRDRRLVLGNADVRINYVVAGTASPLYRNATGDECVYVEAGSGTVETVFGHLDVGPGDYVIIPRATTHRWVPSGDGPLRLYPIEANSHIAPPKRYLSRYGQFLEHSPYCERDLRTPAAPDRVEDENVEVYIKHRGDGPAGLAGSVHVLPHHPFDVVGWDGCLYPYAFNIADYEPITGRIHQPPPVHQVFEGANFVICNFVPRKVDYHPLAVPVPYYHSNVDSDEVMFYVGGDYEARKGSGINVGSISLHPGGYPHGPQPAAIEASLGAERFDETAVMVDTFRPLGLGEAGRISDDGVYAWTWARKP
>NC_017093.1|WP_014444410.1|4504143_4505337_-|4-hydroxyphenylpyruvate-dioxygenase
MSVNDTLTNEERLAELDLDTLKQLVGLVEYDSAADPFPVTGWDAIVWAAGNATQTAHFFQSAFGMELVAYSGPETGNRDHMSYVLKSGAIKFVINGGVAPDSPIIAHHARHGDGITDIALAVPDVDKCIEHARAQGATVLEEPHDVSDEFGTVRMAAIATYGETRHTLVNRTHYTGPYLPGYVARTSARPKKKRIFQALDHVVGNVELGAMDEWVDFYNRVLGFTNMAEFIGDDIATDYSALMSKVVASGNHRVKFPLNEPAVGKKKSQIDEYLEYYGGPGAQHLALATNDILRAVDVLTEEGVEFLATPDSYYSDPELRARIGKVRVPIEELQKRGILVDRDEDGYLLQIFTKPIGDRPTVFFELIERHGSLGFGKGNFKALFEAIEREQAKRGNF
>NC_017093.1|WP_014444411.1|4505714_4505945_-|hypothetical-protein
MADETLIRIRAAAEAYAEAVRQTQRYFDRIDDTTDPSVLIEYAELVRTEEAALADRLDALTVAGLRAESFDGGSEN
>NC_017093.1|WP_014444412.1|4506004_4506205_-|hypothetical-protein
MRTDSRRSLNPGGRLPNGTVMPKFQRMTFPTAQPDARVVHTIAPTGRITRRPTETPRDEALNEDAG
>NC_017093.1|WP_063711169.1|4506210_4507206_-|trypsin-like-serine-protease
MFWKLLPVILAVPIGAVVAAAPAEAIANGTSVPDGRYPFAVKLIDNGIPTADGGRRDSSCSGGLVSPHWVLTAGHCFKDADGRRVSRPVAEESLATVGRTDQSGDDGHETEVVEVRQHGEADVALARLDRGITDITPLRLSRARPAAGQKARLVGYGLTTATAKRTPDRLRTGQFRVTGVEQTEMGLSGVSPKRSTSPCERDSGGPYFTEAKDGAAVVVGVVSRGPACPHTGPDIATRVDAIAPWILSIIKSDLAASPSVKPSKTTKKPAKPGGTPARTTVAAPPAGDPAALTLPPAALLSVPIVLVVLIGLLTAARGKRRYRGRRRNSAR
>NC_017093.1|WP_157434961.1|4507252_4507393_+|hypothetical-protein
MPGRDERHVPGLNFAVSPAVEWHFRTIFTKLGLTSRRDLATALRTG

Crispr_ID: NC_017093_17

• CRISPR_ID: NC_017093_17
• CRISPR_location: 4789874-4789981
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_17

Consensus_repeat	Method
AGAGACCGGACCACCGAACGGCGAAC	CRISPRCasFinder

spacers of NC_017093_17

>17.1|4789900|56|NC_017093|CRISPRCasFinder
GAGAGACCGGACCACCGAACGGCGAACGGCGAACGGCGAACGGCGAACGGCGAACG

CRISPR arrays and Neighbor proteins around NC_017093_17

CRISPR arrays

The CRISPR arrays of NC_017093_17

>merge|NC_017093|17|4789874-4789981|CRISPRCasFinder
CCTGCGCGGACCACCGAACGGCGAACGAGAGACCGGACCACCGAACGGCGAACGGCGAACGGCGAACGGCGAACGGCGAACGAGAGACCGGACCACCGAACGGCGAAC

>NC_017093|17|17|4789874-4789981|CRISPRCasFinder
CCTGCGCGGACCACCGAACGGCGAAC	GAGAGACCGGACCACCGAACGGCGAACGGCGAACGGCGAACGGCGAACGGCGAACG
AGAGACCGGACCACCGAACGGCGAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_014444684.1|4786134_4787436_-|metallophosphoesterase	unknown	unknown	gnl|CDD|277331
NC_017093.1|WP_014444686.1|4788139_4788604_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133384
NC_017093.1|WP_014444683.1|4785678_4786089_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014444689.1|4790934_4792398_-|amidohydrolase-family-protein	unknown	unknown	gnl|CDD|181288
NC_017093.1|WP_014444681.1|4784741_4785434_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NC_017093.1|WP_014444692.1|4794461_4795325_+|extradiol-ring-cleavage-dioxygenase	unknown	unknown	gnl|CDD|153372
NC_017093.1|WP_172666687.1|4799981_4800173_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197715
NC_017093.1|WP_014444679.1|4782129_4783350_-|DUF2236-domain-containing-protein	unknown	unknown	gnl|CDD|378343
NC_017093.1|WP_041829982.1|4785443_4785656_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014444687.1|4788600_4789137_+|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl|CDD|223672
NC_017093.1|WP_014444691.1|4793674_4794442_+|citryl-CoA-lyase	unknown	unknown	gnl|CDD|235748
NC_017093.1|WP_014444680.1|4783366_4784581_-|DUF2236-domain-containing-protein	unknown	unknown	gnl|CDD|378343
NC_017093.1|WP_014444695.1|4796633_4797122_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_017093.1|WP_014444685.1|4787522_4787993_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014444696.1|4797174_4797495_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NC_017093.1|WP_014444690.1|4792553_4793690_+|CoA-transferase	unknown	unknown	gnl|CDD|367110
NC_017093.1|WP_014444678.1|4779904_4782133_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	unknown	unknown	gnl|CDD|224446
NC_017093.1|WP_014444693.1|4795321_4795684_+|hypothetical-protein	unknown	unknown	gnl|CDD|153390
NC_017093.1|WP_014444694.1|4795680_4796637_+|zinc-binding-alcohol-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|223677
NC_017093.1|WP_014444688.1|4790126_4790930_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|131484

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_014444684.1|4786134_4787436_-|metallophosphoesterase	gnl|CDD|277331	cd07385, MPP_YkuE_C, Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain. YkuE is an uncharacterized Bacillus subtilis protein with a C-terminal metallophosphatase domain and an N-terminal twin-arginine (RR) motif. An RR-signal peptide derived from the Bacillus subtilis YkuE protein can direct Tat-dependent secretion of agarase in Streptomyces lividans. This is an indication that YkuE is transported by the Bacillus subtilis Tat (Twin-arginine translocation) pathway machinery. YkuE belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	4.30452e-71
NC_017093.1|WP_014444686.1|4788139_4788604_+|MerR-family-transcriptional-regulator	gnl|CDD|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	2.65913e-46
NC_017093.1|WP_014444693.1|4795321_4795684_+|hypothetical-protein	gnl|CDD|153390	cd07321, Extradiol_Dioxygenase_3A_like, Subunit A of Class III extradiol dioxygenases. Extradiol dioxygenases catalyze the incorporation of both atoms of molecular oxygen into substrates using a variety of reaction mechanisms, resulting in the cleavage of aromatic rings. There are two major groups of dioxygenases according to the cleavage site of the aromatic ring. Intradiol enzymes cleave the aromatic ring between two hydroxyl groups, whereas extradiol enzymes cleave the aromatic ring between a hydroxylated carbon and an adjacent non-hydroxylated carbon. Extradiol dioxygenases can be divided into three classes. Class I and II enzymes are evolutionary related and show sequence similarity, with the two domain class II enzymes evolving from the class I enzyme through gene duplication. Class III enzymes are different in sequence and structure and usually have two subunits, designated A and B, which form a tetramer composed of two copies of each subunit. This model represents subunit A of class III extradiol dioxygenase enzymes. The A subunit is the smaller, non-catalytic subunit. Enzymes that belong to this family include Protocatechuate 4,5-dioxygenase (LigAB) A subunit, 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase (CarB) A subunit, Gallate Dioxygenase and proteins of unknown function.	2.22218e-05
NC_017093.1|WP_014444681.1|4784741_4785434_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.00116e-10
NC_017093.1|WP_014444692.1|4794461_4795325_+|extradiol-ring-cleavage-dioxygenase	gnl|CDD|153372	cd07359, PCA_45_Doxase_B_like, Subunit B of the Class III Extradiol dioxygenase, Protocatechuate 4,5-dioxygenase, and simlar enzymes. This subfamily of class III extradiol dioxygenases consists of a number of proteins with known enzymatic activities: Protocatechuate (PCA) 4,5-dioxygenase (LigAB), 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), 3-O-Methylgallate Dioxygenase, 2-aminophenol 1,6-dioxygenase, as well as proteins without any known enzymatic activity. These proteins play essential roles in the degradation of aromatic compounds by catalyzing the incorporation of both atoms of molecular oxygen into their preferred substrates. As members of the Class III extradiol dioxygenase family, the enzymes use a non-heme Fe(II) to cleave aromatic rings between a hydroxylated carbon and an adjacent non-hydroxylated carbon. LigAB-like class III enzymes are usually composed of two subunits, designated A and B, which form a tetramer composed of two copies of each subunit. This model represents the catalytic subunit, B.	6.58137e-71
NC_017093.1|WP_172666687.1|4799981_4800173_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	9.50828e-14
NC_017093.1|WP_014444679.1|4782129_4783350_-|DUF2236-domain-containing-protein	gnl|CDD|378343	pfam09995, DUF2236, Uncharacterized protein conserved in bacteria (DUF2236). This domain, found in various hypothetical bacterial proteins, has no known function. This family contains a highly conserved arginine and histidine that may be active site residues for an as yet unknown catalytic activity.	1.01479e-13
NC_017093.1|WP_014444687.1|4788600_4789137_+|carboxymuconolactone-decarboxylase-family-protein	gnl|CDD|223672	COG0599, COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown].	1.69105e-26
NC_017093.1|WP_014444691.1|4793674_4794442_+|citryl-CoA-lyase	gnl|CDD|235748	PRK06224, PRK06224, citryl-CoA lyase.	8.0886e-84
NC_017093.1|WP_014444680.1|4783366_4784581_-|DUF2236-domain-containing-protein	gnl|CDD|378343	pfam09995, DUF2236, Uncharacterized protein conserved in bacteria (DUF2236). This domain, found in various hypothetical bacterial proteins, has no known function. This family contains a highly conserved arginine and histidine that may be active site residues for an as yet unknown catalytic activity.	2.60882e-10
NC_017093.1|WP_014444695.1|4796633_4797122_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.0964e-09
NC_017093.1|WP_014444689.1|4790934_4792398_-|amidohydrolase-family-protein	gnl|CDD|181288	PRK08204, PRK08204, hypothetical protein; Provisional.	3.46343e-124
NC_017093.1|WP_014444696.1|4797174_4797495_+|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	3.64289e-17
NC_017093.1|WP_014444690.1|4792553_4793690_+|CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	1.77959e-142
NC_017093.1|WP_014444678.1|4779904_4782133_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	gnl|CDD|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	4.84692e-31
NC_017093.1|WP_014444694.1|4795680_4796637_+|zinc-binding-alcohol-dehydrogenase-family-protein	gnl|CDD|223677	COG0604, Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only].	1.37368e-35
NC_017093.1|WP_014444688.1|4790126_4790930_-|helix-turn-helix-domain-containing-protein	gnl|CDD|131484	TIGR02431, p-hydroxybenzoate_hydroxylase_transcriptional, beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family. Member of this family are IclR-type transcriptional regulators with similar DNA binding sites, able to bind at least three different metabolites related to protocatechuate metabolism. Beta-ketoadipate is the inducer for PcaR, p-hydroxybenzoate for PobR, and protocatechuate for PcaU. [Regulatory functions, DNA interactions].	1.13176e-84

Protein sequences

>NC_017093.1|WP_014444687.1|4788600_4789137_+|carboxymuconolactone-decarboxylase-family-protein
MSTTQHDVPVTARPDGTATAQHDGAATAQPEVTSAAAQHDVTSVASRDRRRHGLDVLSRIDGDAGTSVIDALAGISPALGHHVAAFAFGDIYDRPGLDPRSRQLVTIGVLTALGGCEPQLKVHVGAALNVGLSPDEIVEAMLHATVYAGFPRALNATFAAKEVFEARGIPMPPTGDHA
>NC_017093.1|WP_014444686.1|4788139_4788604_+|MerR-family-transcriptional-regulator
MNANEQLAQALRLAVDPPGGVSVHALQDLVADDDSRQWDIATAARHVGASPHTLRYYERIGLVTVPRNPAGHRIYDTAAIRRLVFLTRMRTSGMPISDLRQYIDLVDRGDVTIPDRLDLLLEHRDTLRSQIAQLQLALAATEYKIATYGGATQP
>NC_017093.1|WP_014444685.1|4787522_4787993_-|hypothetical-protein
MSDPMLDNRTARSDWAEPDGVLANYVSLTDQLVEPVDPGTPFTLTVGGLVVDGDLIPEWQWFAELSELNDHEDAYYVGMAEYVKEQSDLAHAAVKSRDIGKEISYREFQALSAPTKYIHLRDAHVTRPGQTDRGPGKLWRGRLRDVSGWIPGRAAE
>NC_017093.1|WP_014444684.1|4786134_4787436_-|metallophosphoesterase
MILLFLLIFAVVLAILATAHWYVWRRLIRDTTAPRTRWRRAGTAVFIAGPVLAVGALAGEQAGLPHTAAGIVAWPGYLWLALFLYLFLGVLAGEVVRPLISRLLAARSKEPASAALTKEPASVALSKEPATAGAITTPVKETVPVGATGPDSQEPGPSPVPGELVSRRVFVSRVVGGAAAVVAAGTVGAGTYSVMNGPSIKRITVPLAKLPRSAHGMRIAVVSDVHLGPVLGRRFCQGVVDTINSTQPDLIAVVGDLIDGDVEDLADSVEPLRGLTSRLGTFFVTGNHEYISGVEPWVEKVRELGMQPLRNARVPLAGLDLAGVDDVQGVPDFGAALDDRDRSRPVVLLAHQPVNIHEAVEHGVDLQLSGHTHGGQMWPGNYIAELANPTNSGLERYGDTQLYVSRGAGAWGPPVRVGAPSDITIVQLASPQA
>NC_017093.1|WP_014444683.1|4785678_4786089_-|hypothetical-protein
MERGANVPSMSPLRLLTGHELEFIRLGHAIVLGFSGDRHVIIEAPAHLDGPDGRVDIEPDDPSDAIGTLLGDVVREARAGEAGELRISFVSGAELLVDADAFAESWAVAGPDGFLIVCLARGELAMWGAASGELCR
>NC_017093.1|WP_041829982.1|4785443_4785656_-|hypothetical-protein
MTVLQAFGVDGPARPLAGGQGTSWVAGELVFKPDDGVLATTNERVRSPGEGAGLRDEARRYELAAAAIGL
>NC_017093.1|WP_014444681.1|4784741_4785434_+|TetR/AcrR-family-transcriptional-regulator
MEQPLPALGAVPGSDSLLGRAIAEVFAGGDLTDDLPADVREDDVTTRLLDTAYQHFCRIGIRRSTMEEVARRAGVSRVTAYRRFATKDALVKHVIRREFRRYFAQFLTEVQQGSTAADRVVIGFVSSLRAIRNNPLIGGLMITEPDVLIPSIVGDGGLMLGTVQRFVAGQLRQEQHVGTISPGVDVELVAELMTRLCCSFLVTPSFVVDLDDPEQLGTLARRFLTPMLNG
>NC_017093.1|WP_014444680.1|4783366_4784581_-|DUF2236-domain-containing-protein
MEPLSRRNMLRAGGALGALGALSVATPAKAWTWSPQGSVAGAGVGADPRWVWDEEADPLVASLIDRGDVPMVNTLLRTWKKNGQPLPAGLPADLHAFMERARQLPPWADQAKLDLAVDFNEKRGLYLGVLYGLASGMMSTVIPKEALAVYYSQGGADMKDRISKTAKLGYDIGAVNAYRPDGEMIVTAVKTRLVHAAVRHLLPQSPYWTQVAEEDIPISQRDIMVTWHSLPTTVMRKLTDWKVPIPEAESQAFLHSWQVGAYLLGVRDEYIPNSWAEANSQATQVLDPVLRPTPEGIKLADILLNLGKGIDGGLLTKGILGSFTRFMLGDEVAGWLKIPRELVWDPLLRTAWGPFIAVREGLLPFPLAPKAYWLFDEFLRKAALLFLSEAKPISIEIPLTNRPT
>NC_017093.1|WP_014444679.1|4782129_4783350_-|DUF2236-domain-containing-protein
MSELSRRKLLMSGGALGAFGALGLATPAWSRDVSPWTWSPTGSIAGSGSGADPRTIFDAEADPVSARLLDSGAVPEVNRLLWNWTRNDQPLPAGLPGYLVDFIEHARQLPAWADTAKLERAAQFNKSRGLYLNLLNGVGGGMLSTAIPKEAWSVYYSKGGADMEDRVAKTSLLGFSVGALNAYRPDGDCVVNAVKTRLVHAAVRHLLPQSPHWQWGPIISQEDILVTWHTLPTYAMRKLREWDVRISAADAQAYLHVWQVTAHLLGVRDEYIPATWAAANAQSDQVLPPNMGPTREGVELTDILLGQLAEQTSPGSVSRPLVNALARYLVGDQVSDWDGIKREPIWGPLIARLWPLLVKFREGLIPLPLVPEAAWVIDEAARQYILFFLTKGQETKIEIPTINRPE
>NC_017093.1|WP_014444678.1|4779904_4782133_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit
MKRRSFLGFVLAGPVLVTAAPTRADADVTEILDLNDIMTAAALPTSGLISVEVNPDGTVSFALPRAEVGQGITTSTAMLIAEELSVPVHRVRVTLADARPELIFNQLTGASNTTIATYTPIRVAAAVARQRLLAAAASLWNAPVAALRLDAGAITDDEGHRVDIGALAVKAASPRTLSVPVELAPRESFTVIGRPQNRIDARDAVTGRKKFAMDLDVPGAKPTMVCRPPTINGKPGPVANLAEVLAMPGVTDVVTISTGVAVRADTFGQCIDAVRALRVTWRAGTVEGQSDQSVLAKLAAAELPLGPRPLTPVVEGRFTFYFRSNSALETNCAVADVRPGRAEIWSALKSPIVAQQTIAAKLGLPLGKVTVHVTEGGGSFGRKLFFDAALEAAEVSQKIGKPVKLMWHRADDSRQGRTHPMATSRVRIAYAGGLVLGFEQRHTSVTTDLGHGLGELLTAMAAQLPIGDAAFAQTFFQFSHTSPYRFGVHTRLLAETGKGFNTGSMRNVYSPDTTCARELMIDQLASRMGKDPFEMRRDFLRDERARAVLRAAAEAGEWGRSMPAGTAQGIAFHSEYKGVSACLVEIDCRPSTVNRPIRDGVGGPRVTKVVFAVDVGLAVNPRGLEAQMMGCAMDGIALALTSSLHLRDGYFLEASWDNYFYTRQWNTPPDLRVIVMPPTSDQPGGAGELGVAASMAAVACAYGRAAGTMPTSFPINHGTLSFTPKPTVPPIPASPSVRGFHA
>NC_017093.1|WP_014444688.1|4790126_4790930_-|helix-turn-helix-domain-containing-protein
MNDTGRGAGPDFIEALARGLDVLRTFRPGTPSMTLSEIAGLTGLARPTVRRILITLETLGYVRGAGRGYALTPRVLDLGMAYIDSLSMWDVARPHMEKLVAQTNESTSMAQLDGSDIVYVARVAVPKIVTLAVSIGTRFPAAATSLGKVLLAALPPAAVPGVLAEPSRSGITPRWQPSAAELESTLREVRAKGWALADQDLAPGIRSVATGVRNGDGEVVAAVNVTVHAAETSVDTLLDDHLPRLLRTAADIGHDWSRTATIPSATA
>NC_017093.1|WP_014444689.1|4790934_4792398_-|amidohydrolase-family-protein
MSERPVVFRGGLVLTMDDSRTVLPGADVLVADGRIAAVGHGLSVPDDAEVIDASGGIVMPGMIDTHRHLWQTAMRGYGTDWTLTQYFVWYYLESGKHFRPEDIYAGNLLGAIEAIDAGVTTTVDWSHGLQTPQHADAAVDALESVPGRFVLAYGNLQQGPWEWATSGGFRDFHRRRVDGGRLAGFQLAFDVTGDPAFPEKAAFEVARELGVAVTTHAGVWGATNDEGIRLMYENGFMTPGTVYVHAATLSSDSYHRIAATGGSVSVSTESEQSAGQGYPPTWALRRHGVPVSLSMDTSVWWSGDLFSAMRTTLSADRSREHLEAHGKQETVTHHHLRAEQVVEWATRGGAKALGLDAELGALTPGRKGDVVLIKNDASPAMFPILHPYGHVVFQAQRGDVHTVVVGGAVVKRDGRLVDAVARSDGRPAGADLRTARAKVAATVDHLRETLGEEAWQRGQNPDLPQAELFDNPYQYTDYDAGTAQWKH
>NC_017093.1|WP_014444690.1|4792553_4793690_+|CoA-transferase
MVEQSRGPLDGLLVADFSRILAGPYATMLLADLGAQVIKVESPAGDDTRTWMPPIRDGVATYYLGINRNKRSIALNLKDPDDRAAAQELARRADVLIENMRPGGLARFGLDYDTVAASNAGIIYASISGFGSGAGASMPGYDLMVQAISGLMSLTGDPDGSPYRAGISVFDVMAGLHANMGILAALHRRAATGRGQHVEVNLLSSALSGLVNHSSGYVAGGTVPFRMGNAHPSLFPYEPLPTADGELIVIAGNDGQFRKLCHVLGLPDLPGDPRFGRNQDRTANREQLRPLLVERLVTRTKEEWFRDLLAAGVPCAPINTIDGGVALAEELGLAPVVTVEGVPGVRNPITFSETPARYELPPPGLDEHGEEIRAWLKD
>NC_017093.1|WP_014444691.1|4793674_4794442_+|citryl-CoA-lyase
MAEGLKFPTGLGTSDADSISLLGQDLAADLMGKVGFGELAFWLVAGRRPNPGEVRLFEAVLVALADHGFTPTAIAARLTYLSAPDSLQGALAAGLLGGGSRFLGVTEDCGRFLADVLAAADSDDYDGIALRAVEEARAAKRFIPGLGHPVHKEQDPRTPVLIAIATEEGLYGPHLRLFEAIGRVHPQILRRTLPLNGAGVCGAALADLGLPVDLLRGFALLARAAGLLGQIAEERRRPIAGDIYRTVDRNAVYEP
>NC_017093.1|WP_014444692.1|4794461_4795325_+|extradiol-ring-cleavage-dioxygenase
MASIVAVIASTHHPFYYRASTSTGDDRPPFADEWTRKILAFRETLTRAKPDVLVMVGSDHFHQLWLDNMPQFLVGKAPFYDANWYNEEREFGLPRMVLKGQEDLSSHILRSGLDAGFDLAFSNELRIDHSVTCPIITLRPEADLPIVPIYTNIFAPPLPQPSRFVKLGETIREIVEQWPSQLRVAVIGTGHLSLELGGPRQFGPHGPDPAFDEKAVGWIANGDLDGCLREVTLDSLHTPGNATHGFMDFMLMMGVAGAGVKADYVDTLDLFHTMEAYFTWYPNGAPA
>NC_017093.1|WP_014444693.1|4795321_4795684_+|hypothetical-protein
MSRYLLNKFLFTVDRDPALVERYRADPGELVRWWESSMANTILNCHSGEASTWLTFTAEEREALIAHDHVRLFGLGAHPFLTLTLFIAMFERDNTEPLEYQKAYGTALAAFALPYPDITT
>NC_017093.1|WP_014444694.1|4795680_4796637_+|zinc-binding-alcohol-dehydrogenase-family-protein
MIDAAVVRICGQPPMPERRPAPVPGDGEFCIRVAAAPITPLDVLCASGTSYFGVPATPYVPGVQGVGHLDDGTAVWFATAAGMRPGDGSMASIVTAAGDDVVTLPPGTPLIPVAALGLSAVAAHAALRAAGDDLGQVVVLGAGGTVGQAAIQLALLGGARRVIAVARSPEALARATDLGAAATVPLLPGDSETGLADCLRDAADGPVDLVIDPVFGMPAAAALRVLRPGGTLVNLGSAAGATAPIDSATLRSGSLRIVGHTNNALSPAQRAGALTDIAAHAAAGRLTVAHETVPLAAVAEAWTRQAIGLARSRMIITP
>NC_017093.1|WP_014444695.1|4796633_4797122_+|GNAT-family-N-acetyltransferase
MTKVVTYVEMTSLDDLRPAAPVPGLALEPLDPASPLVIELQVRIGAPYGWKSASRTPEEWAAHLAAHPDRRYFAVTFEGEPAGMVACHQRPGDDVEIETFGLVPEFTGRRLGGYALTLGIRQAWSLTPGVKRVWLHTSTQDHPNALPNYHRRGFRTFATESR
>NC_017093.1|WP_014444696.1|4797174_4797495_+|STAS-domain-containing-protein
MERPLAITPTTEPAGIRLRGTLGASTLPLLETSLERLLDQTGDVVLDLAGVTFVDSAGLRALVRAAASLEARGRRLLLENPRPQLFRLAEAVGYGIPAATMQSPGR
>NC_017093.1|WP_172666687.1|4799981_4800173_+|helix-turn-helix-transcriptional-regulator
MPPAAAGADRWSRLTVTELAVVEKIAAGATNREVAAAMFLSPHTVNTHVRHAFTKLGITPASS

Crispr_ID: NC_017093_18

• CRISPR_ID: NC_017093_18
• CRISPR_location: 5794295-5794399
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_18

Consensus_repeat	Method
GCGACCTGAGCACCACCGCGCGACCTGAGC	CRISPRCasFinder

spacers of NC_017093_18

>18.1|5794325|45|NC_017093|CRISPRCasFinder
ACCACCGCGCGACCTGAGCGCTGCCGCGCAACCCGGGACCGCCGA

CRISPR arrays and Neighbor proteins around NC_017093_18

CRISPR arrays

The CRISPR arrays of NC_017093_18

>merge|NC_017093|18|5794295-5794399|CRISPRCasFinder
GCGACCTGAGCACCACCGCGCGACCTGAGCACCACCGCGCGACCTGAGCGCTGCCGCGCAACCCGGGACCGCCGAGCGACCTGAGCACCACCGCGCGACCTGAGC

>NC_017093|18|18|5794295-5794399|CRISPRCasFinder
GCGACCTGAGCACCACCGCGCGACCTGAGC	ACCACCGCGCGACCTGAGCGCTGCCGCGCAACCCGGGACCGCCGA
GCGACCTGAGCACCACCGCGCGACCTGAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_014445561.1|5802032_5802632_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014445545.1|5783305_5784082_+|exodeoxyribonuclease-III	unknown	unknown	gnl|CDD|197320
NC_017093.1|WP_014445543.1|5780088_5782416_+|bifunctional-diguanylate-cyclase/phosphodiesterase	unknown	unknown	gnl|CDD|236645
NC_017093.1|WP_014445558.1|5799582_5800350_-|RNA-polymerase-sigma-factor-SigF	unknown	unknown	gnl|CDD|274373
NC_017093.1|WP_014445560.1|5801403_5801871_+|PPOX-class-F420-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274679
NC_017093.1|WP_014445562.1|5802725_5803538_+|fused-MFS/spermidine-synthase	unknown	unknown	gnl|CDD|223498
NC_017093.1|WP_014445563.1|5803674_5805639_+|alpha-1,4-glucan--maltose-1-phosphate-maltosyltransferase	unknown	unknown	gnl|CDD|200482
NC_017093.1|WP_014445559.1|5800577_5801381_+|ROK-family-protein	unknown	unknown	gnl|CDD|224851
NC_017093.1|WP_014445554.1|5794407_5796642_-|CHASE-domain-containing-protein	unknown	unknown	gnl|CDD|223715
NC_017093.1|WP_014445546.1|5784146_5785814_+|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NC_017093.1|WP_014445549.1|5787435_5788185_-|hypothetical-protein	unknown	unknown	gnl|CDD|379155
NC_017093.1|WP_014445547.1|5785810_5786830_+|cobalamin-B12-binding-domain-containing-protein	unknown	unknown	gnl|CDD|227345
NC_017093.1|WP_157435092.1|5792694_5793771_-|LCP-family-protein	unknown	unknown	gnl|CDD|367673
NC_017093.1|WP_014445550.1|5788253_5788634_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014445551.1|5788709_5792639_-|ATP-dependent-RNA-helicase-HrpA	unknown	unknown	gnl|CDD|182986
NC_017093.1|WP_157435440.1|5798074_5798953_+|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239486
NC_017093.1|WP_014445548.1|5787006_5787243_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014445557.1|5798949_5799546_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014445555.1|5796735_5797842_-|sporangiospore-maturation-cell-wall-hydrolase-GsmA	unknown	unknown	gnl|CDD|224619
NC_017093.1|WP_041830086.1|5793919_5794288_+|response-regulator	unknown	unknown	gnl|CDD|381099

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_014445545.1|5783305_5784082_+|exodeoxyribonuclease-III	gnl|CDD|197320	cd09086, ExoIII-like_AP-endo, Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases. This subfamily includes Escherichia coli ExoIII, Neisseria meningitides NExo,and related proteins. These are ExoIII family AP endonucleases and they belong to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds. AP endonucleases participate in the DNA base excision repair (BER) pathway. AP sites are one of the most common lesions in cellular DNA. During BER, the damaged DNA is first recognized by DNA glycosylase. AP endonucleases then catalyze the hydrolytic cleavage of the phosphodiester bond 5' to the AP site, and this is followed by the coordinated actions of DNA polymerase, deoxyribose phosphatase, and DNA ligase. If left unrepaired, AP sites block DNA replication, and have both mutagenic and cytotoxic effects. AP endonucleases can carry out a variety of excision and incision reactions on DNA, including 3'-5' exonuclease, 3'-deoxyribose phosphodiesterase, 3'-phosphatase, and occasionally, nonspecific DNase activities. Different AP endonuclease enzymes catalyze the different reactions with different efficiencies. Many organisms have two AP endonucleases, usually one is the dominant AP endonuclease, the other has weak AP endonuclease activity. For example, Neisseria meningitides Nape and NExo, and exonuclease III (ExoIII) and endonuclease IV (EndoIV) in Escherichia coli. NExo and ExoIII are found in this subfamily. NExo is the non-dominant AP endonuclease. It exhibits strong 3'-5' exonuclease and 3'-deoxyribose phosphodiesterase activities. Escherichia coli ExoIII is an active AP endonuclease, and in addition, it exhibits double strand (ds)-specific 3'-5' exonuclease, exonucleolytic RNase H, 3'-phosphomonoesterase and 3'-phosphodiesterase activities, all catalyzed by a single active site. Class II AP endonucleases have been classified into two families, designated ExoIII and EndoIV, based on their homology to the Escherichia coli enzymes ExoIII and endonuclease IV (EndoIV). This subfamily belongs to the ExoIII family; the EndoIV family belongs to a different superfamily.	2.1852e-116
NC_017093.1|WP_014445543.1|5780088_5782416_+|bifunctional-diguanylate-cyclase/phosphodiesterase	gnl|CDD|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	4.03228e-99
NC_017093.1|WP_014445558.1|5799582_5800350_-|RNA-polymerase-sigma-factor-SigF	gnl|CDD|274373	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily. This group of similar sigma-70 factors includes clades found in Bacilli (including the sporulation factors SigF:TIGR02885 and SigG:TIGR02850 as well as SigB:TIGR02941), and the high GC gram positive bacteria (Actinobacteria) where a variable number of them are found depending on the lineage.	3.81327e-110
NC_017093.1|WP_014445563.1|5803674_5805639_+|alpha-1,4-glucan--maltose-1-phosphate-maltosyltransferase	gnl|CDD|200482	cd11344, AmyAc_GlgE_like, Alpha amylase catalytic domain found in GlgE-like proteins. GlgE is a (1,4)-a-D-glucan:phosphate a-D-maltosyltransferase, involved in a-glucan biosynthesis in bacteria. It is also an anti-tuberculosis drug target. GlgE isoform I from Streptomyces coelicolor has the same catalytic and very similar kinetic properties to GlgE from Mycobacterium tuberculosis. GlgE from Streptomyces coelicolor forms a homodimer with each subunit comprising five domains (A, B, C, N, and S) and 2 inserts. Domain A is a catalytic alpha-amylase-type domain that along with domain N, which has a beta-sandwich fold and forms the core of the dimer interface, binds cyclodextrins. Domain A, B, and the 2 inserts define a well conserved donor pocket that binds maltose. Cyclodextrins competitively inhibit the binding of maltooligosaccharides to the S. coelicolor enzyme, indicating that the hydrophobic patch overlaps with the acceptor binding site. This is not the case in M. tuberculosis GlgE because cyclodextrins do not inhibit this enzyme, despite acceptor length specificity being conserved. Domain C is hypothesized to help stabilize domain A and could be involved in substrate binding. Domain S is a helix bundle that is inserted within the N domain and it plays a role in the dimer interface and interacts directly with domain B. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NC_017093.1|WP_014445562.1|5802725_5803538_+|fused-MFS/spermidine-synthase	gnl|CDD|223498	COG0421, SpeE, Spermidine synthase [Amino acid transport and metabolism].	2.10413e-16
NC_017093.1|WP_014445559.1|5800577_5801381_+|ROK-family-protein	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	3.79991e-32
NC_017093.1|WP_014445554.1|5794407_5796642_-|CHASE-domain-containing-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.37556e-47
NC_017093.1|WP_014445546.1|5784146_5785814_+|serine/threonine-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	1.16733e-40
NC_017093.1|WP_014445549.1|5787435_5788185_-|hypothetical-protein	gnl|CDD|379155	pfam13385, Laminin_G_3, Concanavalin A-like lectin/glucanases superfamily. This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.	5.12793e-09
NC_017093.1|WP_014445547.1|5785810_5786830_+|cobalamin-B12-binding-domain-containing-protein	gnl|CDD|227345	COG5012, COG5012, Predicted cobalamin binding protein [General function prediction only].	2.84431e-17
NC_017093.1|WP_157435092.1|5792694_5793771_-|LCP-family-protein	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	4.61335e-52
NC_017093.1|WP_014445560.1|5801403_5801871_+|PPOX-class-F420-dependent-oxidoreductase	gnl|CDD|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	1.8926e-37
NC_017093.1|WP_014445551.1|5788709_5792639_-|ATP-dependent-RNA-helicase-HrpA	gnl|CDD|182986	PRK11131, PRK11131, ATP-dependent RNA helicase HrpA; Provisional.	0
NC_017093.1|WP_157435440.1|5798074_5798953_+|phosphatase-PAP2-family-protein	gnl|CDD|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	9.31053e-09
NC_017093.1|WP_014445555.1|5796735_5797842_-|sporangiospore-maturation-cell-wall-hydrolase-GsmA	gnl|CDD|224619	COG1705, FlgJ, Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion].	1.55205e-42
NC_017093.1|WP_041830086.1|5793919_5794288_+|response-regulator	gnl|CDD|381099	cd17546, REC_hyHK_CKI1_RcsC-like, phosphoacceptor receiver (REC) domain of hybrid sensor histidine kinases/response regulators similar to Arabidopsis thaliana CKI1 and Escherichia coli RcsC. This family is composed of hybrid sensor histidine kinases/response regulators that are sensor histidine kinases (HKs) fused with a REC domain, similar to the sensor histidine kinase CKI1 from Arabidopsis thaliana, which is involved in multi-step phosphorelay (MSP) signaling that mediates responses to a variety of important stimuli in plants. MSP involves a signal being transferred from HKs via histidine phosphotransfer proteins (AHP1-AHP5) to nuclear response regulators. The CKI1 REC domain specifically interacts with the downstream signaling protein AHP2, AHP3 and AHP5. The plant MSP system has evolved from the prokaryotic two-component system (TCS), which allows organisms to sense and respond to changes in environmental conditions. This family also includes bacterial hybrid sensor HKs such as Escherichia coli RcsC, which is a component of the Rcs signalling pathway that controls a variety of physiological functions like capsule synthesis, cell division, and motility. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	5.03886e-28

Protein sequences

>NC_017093.1|WP_041830086.1|5793919_5794288_+|response-regulator
MIVVAEDHEDIRYVLKRSLERAGHRVVAAADGAAALEAVREHRPDLVVTDVDMPRMTGLDLCRAIRADDDLRHIPVVVASGSLLPGDESAEAAGASATLLKPFVPAQLLALIARLLDPAPRA
>NC_017093.1|WP_157435092.1|5792694_5793771_-|LCP-family-protein
MGVLVDAENDLEPVKPRRFAGFRKLAGWQKALIVLGVLLLVIAGGLTGTGFYLYERYDNKVSRESLLPSRSAEDVARSEENWDSGPLNLLLLGSDSRAEEPDETSPIGERSDTIMLLHISKNRDHATLMSIPRDSYVEVPAGGSWKGGKNKINSAFAFGGAPLTAETVTKLTGITLDGAMIADFASIREMVDAVNGVNVCTYAKVTSLHTGRVWEPGCHDMNGEVALDFVRQRYSVEGGDFGRMRNQQLVVKALVAKVQSSGAMTNPLKLDSLLGIAAEALTVDDRLDLRDLAFKVRDLRPDNIDYLTVPDTGASLDTPAGSAVELDPDLSVSLFKAVADDTVQQWLAENPGQAAPGS
>NC_017093.1|WP_014445551.1|5788709_5792639_-|ATP-dependent-RNA-helicase-HrpA
MSISPATPAVAELRSRISELLPRDEHRLGRRLEGTRRIRDDAARSGALAEIAAEVDQARLRLEARIARVPRVTYPEALPVSGRKDDIAAAIRDHQVVVVAGETGSGKTTQIPKICLELGRGLRGQIGHTQPRRIAARTVAERIAEELDRPLGATVGYKVRFTDQVSDDTMIKVMTDGILLAEIQNDRMLRRYDTLIIDEAHERSLNIDFILGYLRELLPKRPDLKLIITSATIETERFAAHFADAAGTPAPVIEVSGRTYPVEVRYRPLVTTRLIGDDEEIREEPIDQIDGIAAAVDELPTDGDILVFLSGERDIRDTADALTKRDLRNTEIVPLYGRLSAAEQHKVFERHTGRRVVLATNVAETSLTVPGIRYVIDPGTARISRYSNRLKVQRLPIEPVSQASANQRKGRCGRTSDGICIRLYSEEDFEQRPEFTEPEILRTNLASVILQMTNLGLGDLAKFPFIDPPDRRNITDGVKLLEELGALTDRKLTPLGRQLAQLPVDPRLARMVIEADRQECVAEVMVIAAALSIQDPRERPADKQQQADEKHARFTDKESDFFSYLNLWRYLREKQQELSGNQFRRLCRSEFLNYLRVREWQDIYAQLKQVTRTLGLSVKEDWEAGVAAQPVHTALLAGLLSHIGFKDPEKREYLGARGAKFAVFPGSALFKRQPRWVMSAELVETSRLWGRVNARIEPEWAEKLAPHLVKRTYSEPHWDRKMGAVMAFEKVTLYGLPIVPRRRVGYGKVDPVVSRELFIRHALVEGDWETHHKFYAENNRLLKQITEIENRARRRDIAVDDETVYALYDARIPADVVSSRHFDGWWKKARRDDPDLLTFTREDVVNAGRDTVDPNAFPDAWLAGGVKLPLHYEFNPDSHADGVTVKVPLDLINKIDADDFGWSVPGFRKDVVIALIRALPKQLRTSFVPVPDWAEAVLDRVPARRGPLPDAIGAELRRLSGTVVPADAWRPDQVPEHLRMNFRVVNEAGEVVAEGRDVDVLRRQLAPKVQATISRAAGNLERRGITTNDFGALPRKVAQTRGGYEVNVWPALVDEGTSIAVKVFETEPEQRVAMIAGTRRLLLLTLPPAAKYLGGRLDNKAKLELSRANPYRSIADLLDDCAGAAVDRLVADNGGPVWSSVEFASLRDHVRQDLVDAVANVVTQVQAVLATAYDVEQRVRTLRDPALLPALADIRQQLKGLVHPGFVTETGWRQLHHMPRYLRGIVYRLDRLGGGLGRDRQLTTQIHEIESEYRELRAEAHPGGPAEEGLREIRWMIEELRINYFAQTLGTAYPISDKRIYKAMDALPL
>NC_017093.1|WP_014445550.1|5788253_5788634_-|hypothetical-protein
MTNENLAVAPLAAAVAVRPAGVHLDEMMARIGVDGLAAAFASPALLARVDQHAAAVRDALAGADREVDAEGLAAYARSIAAGVARMGRTLPAPGEAPVTAAAWLDAEWSLLRLLGVCLIAVEAAVL
>NC_017093.1|WP_014445549.1|5787435_5788185_-|hypothetical-protein
MRILNYSILALLAVPASVAALAAPAAVAAPGEVPPAGLVARYNFDGGATGGRVSDLSGRGGPLTVRGANNGLVAFTTIGAGRVASFPGTCAATSPTCPKALLEAADDADLDPGARNFKWAASVRITQAQLSGNANVMQKGVASSASQWKMQISGKAGRAQCVMVAQGTGQKFTATSARPVADGNWHRVVCERSGTALSVSVDGAAGTRVTVPSTLAVDNAMPLRIGGPNLQNGGDMYHGQIDDVYVQLG
>NC_017093.1|WP_014445548.1|5787006_5787243_+|hypothetical-protein
MPAKPFSVSMNVDELAHAEIAAAVQRTTTAAGEDHSAAEIAHHGARDPRQAARDRSGRDRAGRAAGASGGRSYAFRRS
>NC_017093.1|WP_014445547.1|5785810_5786830_+|cobalamin-B12-binding-domain-containing-protein
MSGVAVHVALDHYLELIGDGDEQGAIDVAAALLDSGMPAQQVISDLIGAAQRRVGELWASNEWGVAREHAATAVSERVLAAVGARTAVPATRGRITLACVDGEWHGLPARMLAEMLRLDGWRVDFLGASVPGRHLITHLHQTGPDAVALSCMIPTRLPRAHAAITACRAAGIPVIAGGRGFGPDGRYARLLGADAWAATGEEAVARLADDWPPPYVADHPGTFLGDEEYTHLVRSRPQLITCAMDRLPAVYPEAHHYDQAQIDATAEDIGHIADFLAAALYVGDEAIFTDFVEWTAEVLSSRGVPPGALRVGLRLVRDQLVDFPMAIKMIDSAVAGLPR
>NC_017093.1|WP_014445546.1|5784146_5785814_+|serine/threonine-protein-phosphatase
MSALTPAGTGESLQIPAPVLIRAALEATTEGVVLCTAADGIVLFANAAARDLAPELTPGQAVPFTGDSFRTTAGGRHVYGMRRRLDDGHDAWFLRDHTEETEHAAALEVERARSAFLAEAGQRLSASLHVRRCARTTAELAVTHLADAAIVVMPGGTGGQCSWIRLSPGHAPEEGTLAARMLTEVPGLSEALDGFPPIPSRWLDPGQTPGWLFPADLGPVGALLVTPLPGNAETAGALILARLGPQSAFDAGDELLARVFAARAGAALAAAMLYQEQVDTTAVLQADLLPPELPQPEGFELAASYQAARDSLRVGGDFYDVLGPTPGGSDTVIALGDVCGTGPEAAVLTGKVRQTLRALRLVDVAPESMLTVLNQALLQSGRRSRFVTLVVGSVQRVEHGRVRLRLASGGHPPPLVLRTDGTVDVVPTRGTLIGVLPETVVTPATVELSPGELCLLYSDGLTEARGGPSGDEQFGEERLHRQLAGCLGMPGAVVVERLRQLVSDWLHGGPSDDIAIMAVRAHTRPPLSLRGGGAPNASPYLVSARRGDRRSRARS
>NC_017093.1|WP_014445545.1|5783305_5784082_+|exodeoxyribonuclease-III
MRFATWNVNSVKARLPRLLDWLGTTAPDVVCLQETKVAGDGFPAGEVAELGYETAAYGQGRWNGVALLSRIGLDGVRRGFDGEPQFGGVAEARAISAVCGGIRFTSVYVPNGRTPDDPHYAYKLEWLAALRQALVPDLAAGPVVVAGDYNVAPTDADVWDIGVFAGSTHVTAPERAALARLRELGLTDVPARALKGDHPFTYWDYRAGMFHQNKGMRIDLVYASADVAGRVEDALVDRDARKGKGPSDHAPIVVDLKD
>NC_017093.1|WP_014445543.1|5780088_5782416_+|bifunctional-diguanylate-cyclase/phosphodiesterase
MQPALPPLIVRRLWQVMAAFGILATALYALFPDTLISVLSFILLGIGSLAACFFGPRRWGAEPRIAWLLMGTAAITFLIGVLIRPTVTEWHMPWPLLADVFSFSGYVLLGIFLAMLLRQRQSVDRHAVLDGLIVTLSVGMTTTLLLALPAAAITDRSAVLSVIQGTYPLFDVMILLLIINLTFTAKTWPFSLVAITVTMLGMFVGDAAYAIVGVSGQIYASPLFNVPFLIAYTALGVAALHPSVVELSRAAKAPVQEWGWQRLTMLAPALLLPSVMLLTNRTRDPEARILVAVIGAAVFGLLLFRATSAVEAQVAAQLRSEHQASHDPLTSLPNRVSISAEIERLVTVVDPEGHDRVWVYMLDLDGFKWVNDSWGHDTGDQLVIEVGRRLRAAVAAGVPVARVGGDEFLLAYVGEKGGALHLVDDIRGCFARPFPVRDTEVVISASIGISHAAGDAARAAVTAEALMRDADTAMYRAKSEGPGRSSIFDTSMHDQVRERIELEVALRQALAEDQLRVHYQPLVRLETGVPVGAEALVRWEHPERGAIPPMTFIPIAEDAGLIGSIGTWVRQEALRQLGVWRSEGVVGEDFYLSINVSPRQLSEPELPLIVSGEMLRYGVPAHCVALEMTESVMVDGSSVTARVLFELRELGVKLLIDDFGTGFSALGYLRRFPVTGVKIDRSFVIGLGANVEDDEIVRAVVAMSHALGLSVIAEGVETPLQREALYAIGVVNGQGWLWGAAVPAAEFAERWHHAAVATPEMPAMAALYGRHRRTE
>NC_017093.1|WP_014445554.1|5794407_5796642_-|CHASE-domain-containing-protein
MLLTGLLVTVLVAAGLHAAQRDRAERVMDQRHAMALAAVRTEIGRYRQLLEALAAGVATQNELTWEDFDVASAPLEDAELFGAAAMAFVAPVRTADIATAQRLWRARGADGLTLHPESGGPEHFFSIFVRPLADATATPGGVDLRNAPELMDALEESRRIHATTVSDTYVLLRDRDKPVSAQQQSFVFVAPIWTRANTPEFRGWMVLGLRGRNFLSGVLNTISQGQISGDLIATDSDGSQVTIADWSVPGDPDLRRSSGFPVGDRTWTLVTRADYGRLPGAGGQLPVLILVGGLVLTSLLSWLVHVLATGRARARHQVAVATAELSAAEAESRRQAGLLGAVLASISDGVSVVDENGRNLLENPAGKRLMGTTEANDHPQQWQQHYGAFRPDGTTPLPVEEMPLIRALNGESSDGVEIVIRNAQRPEGVLISVDGRPLDPSAGLRGAVAVFRDITDLRRYETDLRVFAGVVAHDLKAPLAAARGHAELALDELPADSPARSRLERMVQAADRMDTMIETLLAYTTARNAPLRLAAVDLEPLAREVIEERAGNREVRWSVGSLPCVRADARMVRHVLDNLVGNAIKYVRPGTVPRVDVTGSLTPGHWVRVEVADDGIGIPEEDRAEVFETFHRTEEAAGYAGTGLGLAICRRIVERHGGEIGVTDNPGGGSRFYFTLPHAEEADMTDTSHHDDGDDAAVRAALERALAERAAIIEAAQLPGLGLAPHPAEERPRRAPRQERQHQD
>NC_017093.1|WP_014445555.1|5796735_5797842_-|sporangiospore-maturation-cell-wall-hydrolase-GsmA
MRHTTRRLLTGAALVLAAGTGLGMAPGAAYAGGLPATVDVSSTLKTRSAPSTAATIVGTVKDGAKISVACAVNGTTVRGKVRTTKVWDRLTSGAYISHSYVRTSAKIPACPPSAQKPKTPKTPKTVTGTVRTTDGPVNTRSGPFTSYATAGMLANNTVVQLVCSAQGTQVTGTVRTTAQWDRLSDGRYISHAYMLSGTLTACPDAPAPILTPAEFIAAAAPGAQQGWRDYGVPPSVTIAQSILESGWGRSGLSSADKNFFGIKCQNGAYGPHATGCHVYTTTECTKAGKCFQTADAFRTYSTMARSFRDHGHFLKVNKRYTPAFAHTRNADKFIEQIWKAGYATDPKYVAKVTGIMKTYDLYRYDTWK
>NC_017093.1|WP_157435440.1|5798074_5798953_+|phosphatase-PAP2-family-protein
MAAPSRSLRHTVTPLLVSVLAAAGVAVTYYTFVRTPLGQAVDTAVMSGGDVDHPRVADVLSKALQYTHLTLLALVCVLAAAFGVLRRRLDLSIGAAFVVGAANLTTQYLKSHLTRPDLDGLAMPNSFPSGHVTAAASVAFVLVLVFPRALRGTIGLIGAGYVTLVAIATVWAEWHRPSDAVAALLIVLACGGVAVWAVRMRRAGAPRPLQLPNMLVMAVLAVTGAVTAAAGLLGLLAVALAERGSPGFVSERFAFLTGSAGIVACVAGTFILWVRLTADEPPAGRPNLGGTK
>NC_017093.1|WP_014445557.1|5798949_5799546_+|hypothetical-protein
MTLPSNDPTTPAPGVPGPGAPAGGSVPPGPAGVPTLPAQTPAAAAPAGPTVVVGTYPEYAQAQQAVDHLSDNKFPVERVSIVGTDLRLVETVLGRLTTARAAAAGAASGAWFGLFIGLLFGIFSDSGWLGVILTTVIIGAIWGAIFGAIAHAATGGRRDFSSRSSLQAAQYAVIADAEVADEARHLLVQLNWRASGAQ
>NC_017093.1|WP_014445558.1|5799582_5800350_-|RNA-polymerase-sigma-factor-SigF
MTVLDTAPTSAADRLAALAAVPAGDPARAALRDRAIEAWLPLARHLAHRYSGRGEPTDDLIQTATVGLIKAVDKFDPERGVDFAGYAIPTIIGEIKRHFRDRTWSVRVPRRLQELRLAITEANSTLTHTLGRSPTVPDIAGHLGISEEDVLEGLEGARAYNATSLSTPISADGNTELGDTLGCEDHEYEIAETRVALGPALAMLDEREQRILTLRFYGNLTQSQIADQVGISQMHVSRLLTKALTKLRRQLDGEI
>NC_017093.1|WP_014445559.1|5800577_5801381_+|ROK-family-protein
MTILGIDIGGSGVKGAPVDTVRGELLAERFRVPTPQPATVESVVEAVAEVAERFGDFERVGITFPGVVVDGVTRSAANVDKSWLDAPAAKLFTERLGKPATVLNDADAAGAAEVAFGAGRDQSGLIMMVTLGTGIGSALFLDGVLIPNTELGHLEIDGKDAELLASDRIREQKELSWEHWAPRVEKYLRHVEMLLSPRLFVIGGGVSKKSEKFFPLIDIRTPMVAATLLNNAGIIGAAVSAEQAAAGPGGQDPGAIQVDAAAQAAKS
>NC_017093.1|WP_014445560.1|5801403_5801871_+|PPOX-class-F420-dependent-oxidoreductase
MARTIATNNRVGRDELLAFLRHRHHAILMTTRKDGRPQSSPNTCGVDTEGRIVISSYPERAKVANVRRDPRVSVCVLSDEWNGAWVQVDGVAEVIDLPDAVEPLVEYFRVISGEHPDWDEYRQAMRDQGKCLIRVTIESWGPIATGGFPPRLADD
>NC_017093.1|WP_014445561.1|5802032_5802632_-|hypothetical-protein
MAGPSTALSPVIAASTHWLARAYPGGESNTVACTLAELQARQAVTVAAWLRYPTEIDAALVAIAGPGGSALLDWKAGSEPEDEYADGEGWRTWVDEVVVSWAACLLADPMLARRGVDSVIAALPAIPDPRPRPHARRGGGLPNEFRRLLQPDARDREAAVLLRHPDLLEPIAAMHRDSLLYLLDAEPAGLAPLGGDRAL
>NC_017093.1|WP_014445562.1|5802725_5803538_+|fused-MFS/spermidine-synthase
MATHGNRGAPLVVTVASGQAELRPDPARPQGWTLLVNDVPQSYVDLADPERLEFPYVRQIGRALRAWSASGRTASGGTASGVPNRILHLGGGALTVPRLAARWWPGVAQKVVELDPLLVDLVRRELPPPPGVEIEVGDARAILETEDPRGYDLIVADVFDGAATPVSVATLGFASAAARALRPGGLLIMNVTDVPPLAWTRIQVATVRAAFDRAGLLGPAAVLRGRRAGNVVLLAGAVPRVPTERDERLLRAGELVVFSGGARPRLDAPR
>NC_017093.1|WP_014445563.1|5803674_5805639_+|alpha-1,4-glucan--maltose-1-phosphate-maltosyltransferase
MTGRFPIEDVTPAVSGGRYPAKAVVGEVVPVSAVSYREGHHALGVNVVWRGPDGETKPFTRMAPGAPGLDQWHATIRPDQVGRWTFTVEAFDDPYRTWRNAVVKKIEAGQGLEDLANDLAEGAEILDLAVKIVPAEDEERVREAAAALRDEQRSLFARVTPGVELEELLWHNPVRQLVTTTRSFALWVDRKRALYSSWYEFFPRSEGAEIGPDATPIKHGTFRTAAERLPAVAAMGFNVVYLPPIHPIGKINRKGRNNTLVARPEDVGSPWAIGSDEGGHDAIHPQLGTLDDFRYFRERTEELGMEVALDLALQAAPDHPWVKQYPQFFTTRADGTIAFAENPPKKYQDIYPINWDNDYRTLRDEVYRVVMHWVNNGVKIFRVDNPHTKAVNFWQWLIPKVKESDPDVLFLAEAFTRPAMMNGLGKIGFTQSYTYFTWRTTAWEMREYMEQLLTTLDWMRPNFWPNTPDILHESLQHGGPPMFKIRAVLATMLTPSWGMYSGYELFEHVARPGAEEYIDNEKFELKPRDWAGAERAGRSLAPYLTRLNRIRDENPALHWLRNLRFHEVDNGAMLCFSKRDDETGNTILVIVSFDSSNVQWGNTTLDMAALGLGWHDRFTVVDQITGATYEWGQFNAVRIDPYVEPAHIFVVQTG

Crispr_ID: NC_017093_19

• CRISPR_ID: NC_017093_19
• CRISPR_location: 6190172-6190257
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_19

Consensus_repeat	Method
GCGTCGGCTACGGCTGGCGTGCG	CRISPRCasFinder

spacers of NC_017093_19

>19.1|6190195|40|NC_017093|CRISPRCasFinder
GGAGCCGTAGTGCGCGCAGGTAAAAACGGCCGGGAAGCCG

CRISPR arrays and Neighbor proteins around NC_017093_19

CRISPR arrays

The CRISPR arrays of NC_017093_19

>merge|NC_017093|19|6190172-6190257|CRISPRCasFinder
GCGTCGGCTACGGCTGGCGTGCGGGAGCCGTAGTGCGCGCAGGTAAAAACGGCCGGGAAGCCGGCGCCGGCTACGGCTGGCGTGCG

>NC_017093|19|19|6190172-6190257|CRISPRCasFinder
GCGTCGGCTACGGCTGGCGTGCG	GGAGCCGTAGTGCGCGCAGGTAAAAACGGCCGGGAAGCCG
GCGCCGGCTACGGCTGGCGTGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_014445898.1|6196539_6197424_+|carbohydrate-kinase	unknown	unknown	gnl|CDD|238579
NC_017093.1|WP_014445897.1|6194545_6195736_-|elongation-factor-Tu	unknown	unknown	gnl|CDD|237184
NC_017093.1|WP_014445885.1|6181632_6182601_-|SRPBCC-family-protein	unknown	unknown	gnl|CDD|176865
NC_017093.1|WP_014445896.1|6192214_6194422_+|copper-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319783
NC_017093.1|WP_014445890.1|6187448_6187931_-|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|224991
NC_017093.1|WP_041831370.1|6190657_6190954_-|metal-sensitive-transcriptional-regulator	unknown	unknown	gnl|CDD|197385
NC_017093.1|WP_014445883.1|6179390_6180347_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NC_017093.1|WP_014445887.1|6183447_6184026_-|nucleotidyltransferase-family-protein	unknown	unknown	gnl|CDD|133025
NC_017093.1|WP_014445900.1|6198010_6198625_+|DUF4360-domain-containing-protein	unknown	unknown	gnl|CDD|372992
NC_017093.1|WP_014445891.1|6187933_6188812_-|xanthine-dehydrogenase-family-protein-subunit-M	unknown	unknown	gnl|CDD|224238
NC_017093.1|WP_014445895.1|6191240_6192218_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NC_017093.1|WP_014445899.1|6197410_6197761_-|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|227259
NC_017093.1|WP_014445892.1|6188934_6189987_+|XdhC-family-protein	unknown	unknown	gnl|CDD|224886
NC_017093.1|WP_014445901.1|6198804_6199692_+|CDP-alcohol-phosphatidyltransferase-family-protein	unknown	unknown	gnl|CDD|376450
NC_017093.1|WP_014445884.1|6180330_6181533_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|226082
NC_017093.1|WP_014445888.1|6184031_6185033_-|XdhC-family-protein	unknown	unknown	gnl|CDD|224886
NC_017093.1|WP_014445902.1|6199882_6202114_+|alpha-amylase	unknown	unknown	gnl|CDD|200456
NC_017093.1|WP_014445894.1|6191031_6191244_+|heavy-metal-associated-domain-containing-protein	unknown	unknown	gnl|CDD|225328
NC_017093.1|WP_014445889.1|6185058_6187452_-|carbon-monoxide-dehydrogenase-large-subunit	unknown	unknown	gnl|CDD|131469
NC_017093.1|WP_014445886.1|6182597_6183461_-|MoxR-family-ATPase	unknown	unknown	gnl|CDD|223786

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_014445898.1|6196539_6197424_+|carbohydrate-kinase	gnl|CDD|238579	cd01174, ribokinase, Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides and histidine, and for entry into the pentose phosphate pathway. Ribokinase is dimeric in solution.	1.2155e-57
NC_017093.1|WP_014445897.1|6194545_6195736_-|elongation-factor-Tu	gnl|CDD|237184	PRK12736, PRK12736, elongation factor Tu; Reviewed.	0
NC_017093.1|WP_014445885.1|6181632_6182601_-|SRPBCC-family-protein	gnl|CDD|176865	cd07823, SRPBCC_5, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	2.0896e-49
NC_017093.1|WP_014445896.1|6192214_6194422_+|copper-translocating-P-type-ATPase	gnl|CDD|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_017093.1|WP_014445890.1|6187448_6187931_-|(2Fe-2S)-binding-protein	gnl|CDD|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	7.9852e-72
NC_017093.1|WP_041831370.1|6190657_6190954_-|metal-sensitive-transcriptional-regulator	gnl|CDD|197385	cd10148, CsoR-like_DUF156, Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156. This superfamily includes various transcriptional regulators that respond to stressors including Cu(I), Ni(I), sulfite, and formaldehyde. It includes CsoR (copper-sensitive operon repressor) from Mycobacterium tuberculosis (MtCsoR), Bacillus subtilis (BsCsoR), Thermus thermophilus (TthCsoR), and Staphylococcus aureus (SaCsoR), Mycobacterium tuberculosis RicR (regulated in copper repressor, MtRicR), Escherichia coli RncR (formally known as YohL, nickel and cobalt-sensitive), Alcaligenes xylosoxidans NreA (nickel-sensitive), E. coli FrmR (formally known as YaiN, formaldehyde sensitive), and Staphylococcus aureus CstR (CsoR-like sulfur transferase repressor, NWMN_0026.5, SaCstR). CsoR is Cu(I)-inducible, and regulates the expression of genes involved in copper homeostasis. For example, TthCsoR binds the promoter region of the copZ-csoR-copA operon, and represses expression of these genes, which encode the copper chaperone CopZ, CsoR, and the copper efflux P-type ATPase CopA, respectively. In the presence of excess Cu(I), TthCsoR binds this ion, and is released from the DNA, allowing expression of the downstream genes. TthCsoR also senses other metal ions such as Cu(II), Zn(II), Ag(I), Cd(II) and Ni(II). CsoRs form a homotetramer (dimer of dimers). In the case of MtCsoR, two Cys residues on opposite subunits within each dimer, along with a His residue, bind the Cu(I) ion. These residues are conserved in the majority of members of this superfamily. Exceptions include the functionally uncharacterized Bacillus subtilis YrkD where there is an Asn instead of His (C-N-C), E.coli RcnR where there is a Thr instead of the second Cys (C-H-T), or TthCsoR and E.coli FrmR where there is a His instead of the second Cys and which have an additional N-terminal His (not found in those family members having C-H-C) that may also be involved in metal binding (H-C-H-H). A conserved Tyr and a Glu residue facilitate allosteric regulation of DNA binding. SaCstR regulates genes predicted to function in sulfur metabolism; it is thought that oxidation of the intersubunit Cys pair to a mixture of disulphide and trisulphide linkages by sulfite, results in a reduced affinity of SaCstR for the operator DNA. SaCstR exists as a mixture of oligomeric states, including dimers, tetramers and octamers. The sequence of SaCstR was not available at the time this hierarchy was curated and therefore was not included. Escherichia coli RncR represses expression of the gene encoding the nickel and cobalt-efflux protein RcnA. The gene encoding Alcaligenes xylosoxidans NreA is part of the nre nickel resistance locus located on the pTOM9 plasmid from thisbacteria. Escherichia coli FrmR regulates the formaldehyde degradation frmRAB operon.	3.59533e-35
NC_017093.1|WP_014445883.1|6179390_6180347_+|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	5.17703e-35
NC_017093.1|WP_014445887.1|6183447_6184026_-|nucleotidyltransferase-family-protein	gnl|CDD|133025	cd04182, GT_2_like_f, GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	5.39736e-53
NC_017093.1|WP_014445900.1|6198010_6198625_+|DUF4360-domain-containing-protein	gnl|CDD|372992	pfam14273, DUF4360, Domain of unknown function (DUF4360). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 200 and 228 amino acids in length. There is a conserved GCP sequence motif near the N-terminus.	2.23768e-76
NC_017093.1|WP_014445891.1|6187933_6188812_-|xanthine-dehydrogenase-family-protein-subunit-M	gnl|CDD|224238	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion].	2.34077e-79
NC_017093.1|WP_014445895.1|6191240_6192218_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0.000528074
NC_017093.1|WP_014445899.1|6197410_6197761_-|nuclear-transport-factor-2-family-protein	gnl|CDD|227259	COG4922, COG4922, Uncharacterized protein conserved in bacteria [Function unknown].	8.53754e-11
NC_017093.1|WP_014445892.1|6188934_6189987_+|XdhC-family-protein	gnl|CDD|224886	COG1975, XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones].	5.19074e-59
NC_017093.1|WP_014445901.1|6198804_6199692_+|CDP-alcohol-phosphatidyltransferase-family-protein	gnl|CDD|376450	pfam01066, CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase. All of these members have the ability to catalyze the displacement of CMP from a CDP-alcohol by a second alcohol with formation of a phosphodiester bond and concomitant breaking of a phosphoride anhydride bond.	7.42497e-11
NC_017093.1|WP_014445884.1|6180330_6181533_-|VWA-domain-containing-protein	gnl|CDD|226082	COG3552, CoxE, Protein containing von Willebrand factor type A (vWA) domain [General function prediction only].	9.98269e-71
NC_017093.1|WP_014445888.1|6184031_6185033_-|XdhC-family-protein	gnl|CDD|224886	COG1975, XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones].	1.60585e-30
NC_017093.1|WP_014445902.1|6199882_6202114_+|alpha-amylase	gnl|CDD|200456	cd11317, AmyAc_bac_euk_AmyA, Alpha amylase catalytic domain found in bacterial and eukaryotic Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase). AmyA (EC 3.2.1.1) catalyzes the hydrolysis of alpha-(1,4) glycosidic linkages of glycogen, starch, related polysaccharides, and some oligosaccharides. This group includes AmyA proteins from bacteria, fungi, mammals, insects, mollusks, and nematodes. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	3.28579e-129
NC_017093.1|WP_014445894.1|6191031_6191244_+|heavy-metal-associated-domain-containing-protein	gnl|CDD|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	2.70897e-14
NC_017093.1|WP_014445889.1|6185058_6187452_-|carbon-monoxide-dehydrogenase-large-subunit	gnl|CDD|131469	TIGR02416, Carbon_monoxide_dehydrogenase_large_chain, carbon-monoxide dehydrogenase, large subunit. This model represents the large subunits of group of carbon-monoxide dehydrogenases that include molybdenum as part of the enzymatic cofactor. There are various forms of carbon-monoxide dehydrogenase; Salicibacter pomeroyi DSS-3, for example, has two forms. Note that, at least in some species, the active site Cys is modified with a selenium attached to (rather than replacing) the sulfur atom. This is termed selanylcysteine, and created post-translationally, in contrast to selenocysteine incorporation during translation as for many other selenoproteins. [Energy metabolism, Other].	0
NC_017093.1|WP_014445886.1|6182597_6183461_-|MoxR-family-ATPase	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	4.7504e-43

Protein sequences

>NC_017093.1|WP_014445892.1|6188934_6189987_+|XdhC-family-protein
MRDIVDGLLAWRASGTEFALATVVNTWRSAPRRPGAAMAVNASGEVIGSVSGGCVEGAVYAAAQEVLQTGKAQTQVYGVSDGDALEAGLTCGGTIEVMIQPAAALTAIDEVLDAVAAGRPVATVTVPDAQLVVWPAGPAEGTLGDAELDRQAAQQAAGLLAHGRSAIVQACEREVFVQSYAAPARMIVFGAIDFAAAVARIGKFLGYQVTVCDARGVFATPARFPEADEIVVEWPHRYLESTEVDERTVLCVLTHDPKFDIPLLQVALHTPARYIGAMGSRRTCEDRLARLREAGVSEAALSRLRAPIGLDLGARTPEETAVAIAAEIVALSWGGSGAPLTDLTAPIHGA
>NC_017093.1|WP_014445891.1|6187933_6188812_-|xanthine-dehydrogenase-family-protein-subunit-M
MQVPAPFEYERATSVDQAIGLLERLGSSARLVAGGHSLLPMMKLRLANFEYLIDINDLHGELGYIRRSGDEVRIGAMTRHRELLESDALAQVLPIFRDAERVIADPIVRNRGTLGGSLCQADPSEDLSAVCTTLDASCVIRGPGGTERVVGMEEFHVGPYETAVADNEILTEIRIPVKADKSGSAYAKVERRAGDWAVVSAGAAIWLGADNRITDARVGLAAVGPNTTGIPEISAALRGQEPAEALYELAGAIAARSCDPATDTRGTADYKRHLADELTRRTLRKAVERARS
>NC_017093.1|WP_014445890.1|6187448_6187931_-|(2Fe-2S)-binding-protein
MQVTVTVNGVEYTKEIEGRLLLVHFLRDTLGLTGTHWGCDTSNCGTCVVWMDGEPVKSCTVLAAMAGGREVRTVEGLANGAELDPIQEGFRQCHGLQCGFCTPGMLMTCRHLLDNNPDPTEGEIREAISGQICRCTGYSSIVRSVRWTAVHEAEAKAAAK
>NC_017093.1|WP_014445889.1|6185058_6187452_-|carbon-monoxide-dehydrogenase-large-subunit
MTDLQDKRETVFEDNDQKPVGFGRMLRKEDARLLRGRGRFVDDVQLPGMLHLAILRSPFAHANIVSIDTSAAEAAPGVKAVVTGETLKGLGLAWMPTLSNDVQAVLATDKVRFQGQEVAFVVAEDRYLARDALELIDVEYDVLDPVIDVRKALEKDAPIIRTDLEGKNDNHVFDWETGDEEETNRVFAEADVIVKEDIVYPRVHPAPMETCGSVADFDPVEGKLRLWSTTQAPHAHRTLYAIVAGLPEHKIQVIAPDIGGGFGNKVPIYPGYVHSIVGSIVTGKPVKWMEDRSENLISTGFARDYIMRAEIAATAEGKILAIRTNVLADHGAFNGTAAPVKYPAGFFGVFTGSYDLLAAHCKMTAVYTNKAPGGVAYACSFRITEAVYLVERIVDVLAYELQMDPAELRLKNFIQPDQFPYTTKTGWVYDSGDYEPTMRLAMEMAGYEELRKEQALKRAKGELMGIGISFFTEAVGAGPRKNMDILGLGMADGCELRVHPTGKAVVRLSVKTQGQGHETTFAQIIAEELGIPPADIDVVHGDTDNTPFGLGTYGSRSTPVSGAAAALVARKVRDKAKLIASAMLEVSVADIEWVKGSFRVLGDPGKSVTIQDIAMRAHGAGDLPDGMEGGLEAQICYNPSNLTYPHGAYICVVDVDPGTAEVKVRRFIAVDDCGTRINPMIIEGQVHGGLTDGVGMALMEMISFDSDGNCLGASLMDYLIPTALETPDWETGFTVTPSPHHPIGAKGVGESATVGSPPAIVNAVVDALKPFGIRHADMPLTPSRVWDAMRGQATPPI
>NC_017093.1|WP_014445888.1|6184031_6185033_-|XdhC-family-protein
MTTSTAERARQLADARRPFVHATVVRAQEPTSARAGDDAVILADGSIEGFVGGSCAETSVRAAAMGTLRDGNTVLLRVLPEDAADFPETPGALVVVNPCHSGGAIEIFLRPVLPKPLVAVDGNTPIGTAVAELATFLDFEIAPPGAYAGVTAAVVAGLGRDEERAIRGALDAGVGLIALVASHKRAAVVLDAMELSEDERERIRPHAGLDIGARNPKEIALAVLAEIVREMRVGGLAAARKAASSHAATHGEAAALAKEPEFVAGPTLLIGPAAVGRPAAVGTPAGVETPAATAIDPICGMTVTIGPDTPHGVVDGEDYWFCCPGCLKKFTAA
>NC_017093.1|WP_014445887.1|6183447_6184026_-|nucleotidyltransferase-family-protein
MTVTGLVLAAGGSKRLGEPKQLLPFRGRTLLDATLDMARACGFDELLVTLGGSAEAVRAQVDLSGVRVIENPAFASGCGSSVRSAVPHLGDADRLVLLLGDQPGIRPSDVRRVAAVPTPIGICRYTDGLGHPFLFRRETFGELTGLHGDKAVWKLLHAGSYPVTEVDAGGTVPIDVDTREDYERLLRSCEQS
>NC_017093.1|WP_014445886.1|6182597_6183461_-|MoxR-family-ATPase
MNNPDEVVQRLDDVNYLVDDGLAMAIFLSMRLGKPLLLEGEPGVGKTAAAKALAQALDTPFIRLQCYEGLTAGEALYEWNYQRQLLHIRLAEAQGSSIRDADLFTADFLQERPILRAVRHAGPTPPVLLIDEIDRADDEFEALLFEFLGEAAITIPELGTFAATRPPIVVLTSNRSRDLHDALRRRCLYHWIEFPAAERAAAIVRRAVPGASAPLIRNATEFIGRVRRLDLDKAPGLAETIDWVSALAALGVTELAGADVLRTLGTIAKTPDDRELVAGAASQETRS
>NC_017093.1|WP_014445885.1|6181632_6182601_-|SRPBCC-family-protein
MKINNEFVVHIPIDRAWRVLTDLPGIAPCMPGAQLTGVEGDVYKGRVKVKVGPVISDFTGTAQFTAKDDDAYRAVIDAKGRDARSAGNAAAVVTAWLAPSGEDSTQVNVETDLRISGKLAQFGSGMIKEVSGKLLAQFVANLEKKLAAGEESPEPAAAPASPAAPTTGSDAALTTGSDAAPSAGADAAPSAAAVETAPATAVALGGVAPAAPGSSISDISEMSDAAVPDPSAGTVEPAAGRTEVAAGTPDPIAPLNVPSAELAGGAPASSPAPAAERKIESAEPEALDLLEVAGGSIYKRAIPVVIGVAVAAAVIVWAVARP
>NC_017093.1|WP_014445884.1|6180330_6181533_-|VWA-domain-containing-protein
MTAADSAPVLLRGTDRAAFAVAFVARLRRAGLAAGITETDDLVRALSVSPPADRDTLYWTVRIALVRRHADLAVFDEVFATVFDDVVSLPLNRTAGQPGRRDDTVHVKVPAGGDGTADGEGLPWATLPPVVAAAESGADSGLRVPELRPSALAGLADRPFEELDEAQIRALGDDLRAALARWPQRRTRRHAVDPAGRRVALRPTIARARRTGWEAITVVRQRPVREPRRVVLLCDVSESMRAQAAAYLQMMRAFTLVADAEVFAFATTLTRLTPVLRNASAADAVAAAGTAVTDRFGGTRIAGNLRALLDSYQGNALRGGIVIIASDGWDSDPPEMMAAVMARLRRRAYRIVWLNPRAGAPGFTPRVAAMAAALPFCDRLMPAATFADLAACLRELSSRA
>NC_017093.1|WP_014445883.1|6179390_6180347_+|LysR-family-transcriptional-regulator
MTPTQLRAYSAVVRFGSVKRAAAQLAVSESAVSLHIGQLRKELGDQLFSRSATGLTFTPGGLRLASRATEMLGLQDITVLEVSAAGQGRRLLRVGASSLFGEHAAPGLIELFANRAADLDLELSVRNPGSFTEALVERTVDIAIGPPPPLADPAVTSRPVMYYRIVTVASPDHPLAATQPSMRQLREQTWLLGPSAVADSGAIRTLVRRIGVPDDRQQIFQSHAAALEEAKRGRGVAPALSFAVAPEVRKGHLVSFCGGPASLEEVWHSITLAEPATPSAAAELARFASTPRAIQAMMRGTGISKTRFRPSVHVTLWS
>NC_017093.1|WP_041831370.1|6190657_6190954_-|metal-sensitive-transcriptional-regulator
MTNPAPTRGYTATKDNLQSRLRRIEGQVRGIERMVEDDRYCIDILTQISAIQAALDKVALGLLDGHARHCMHEGAQEGRADEMASELMAAVGRLMKRG
>NC_017093.1|WP_014445894.1|6191031_6191244_+|heavy-metal-associated-domain-containing-protein
MQTTTYSVTGMTCDHCANSVSAELGRIAGVTDVRVELASGTVVVTSTEALDRDAVAAAVDEAGYELGVTP
>NC_017093.1|WP_014445895.1|6191240_6192218_+|hypothetical-protein
MRTSVRLGAYAAGLVVIFGVSAGAGKALGPDTSPDKPEAAAPAHTAAHGDPAPGATATHGDPGPSATAAHGDPGPSATAAHGDPGPSATAAHGDPATEAAATPAGLQTVQDGYRLAPLTTTLSTTEPTPFEFRILGPDNRPVTDYTTEHDKDLHLIVVRRDLAHYQHVHPTRKPDGTWTIPLRAGAPGQYRVFADFVTVGHDLTLGVDVPAPGNYQPALLPHPERTADVDGYRVTLGGDLHDPRFTITRGGAAITPEPYLGARGHLVALREGDLAYLHVHPADPDELAFHAEVPSDGVYRLYLDFQHDGNVHTAEFTADTGHTRK
>NC_017093.1|WP_014445896.1|6192214_6194422_+|copper-translocating-P-type-ATPase
MRTPVMNRIELTIGGMTCASCAARIEKKLNRMDGVTATVNYATEKATVTVDGPVTPADLIATVEKTGYTAAEKQQEVDQNSEKADPLATRLWVSAALSVPVILLAMVPAWQFTYWQWASLTLAAPVVVYGGWPFHKAAAVNLRHGAATMDTLISLGTLAAFGWSLWALFFGTAGEPGMTHPFRIAIERSDGAGNIYLEAATGVTTFLLAGRYFESRSKRRAGAALRALLELGAKEVTVLRGGAESRIPVAQLAVGDRFVVRPGEKIATDGVVEDGSSAVDMSMLTGESVPVEVEPGATVAGATVNAGGRLIVRATRVGADTQLAQMARLVEEAQSGKAEVQRLADRISGVFVPIVIGLAAATLGWWFGTGSGWTAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQLGILIKGPEVLESTRRADTIVLDKTGTVTTGRMTLAAVLPAAGQDRDELLHLAASAESASEHPIAAAIASGCGDHLPVSGFTSFEGLGVRASVAGRELVAGRVALLRREGLTIPAEVEDAVAAEEAAGRTAIVAGWDGAARGVLSVADAVKPTSRDAIARLRALGLRPILLTGDNETVARAVAAEVGIDEVIAGVLPADKVETVKRLQSEGRVVAMAGDGVNDAAALAQADLGLAMGTGTDVAIEASDLTLVRGDLSAAVDAIRLSRRTLRIIKGNLFWAFAYNVAALPLAAAGLLNPMIAGAAMAFSSVFVVANSLRLRRFAAAT
>NC_017093.1|WP_014445897.1|6194545_6195736_-|elongation-factor-Tu
MAKSQFVRTKPHLNIGTMGHVDHGKTTLTAAITKVLAERDPATNRYVAFEGIDRAPEEAARGITITIAHVEYETATRHYAHVDMPGHADYVKNMITGAAQVDGAILVVSAQDGSMPQTREHVLLAQRVGVPYLVVALNKADAVDDPELLDLVELEVRELLSEYGFPGDEVPVIPVSALRALEGDPRWTRSIVELLDAVDEYIPIPPRELGEPFLMPIENVLSISGRGTVVTGKVERGTLRAGSPVEIVGLGDTVSSVATGLETFGKILESAEAGDNAAILLRGVKREQVQRGQVVAAPGSVLAHRRFQARMYALTAAEGGRHTPFEQHYRPQFYLHTTDVSGGIDLGDRDLVMPGDTLDAVTVTLGKAVALEPGMGFAVREGNRTVAAGTVTAVLD
>NC_017093.1|WP_014445898.1|6196539_6197424_+|carbohydrate-kinase
MNVVVTGQLARDLVLLVDEMPETGTSADARLRREMLGGKGANQAVALAQLGARPVLVAVRGDDRVGEELIEQARRDGIDVGHVICRPGTETGLIVEALDASGGWRYLQHLPDGVLLTEADVDAAAPTLRSADAVLVQLQQPGPAALAAARHARAGGALVVLDGELPEAERDELLKLADVIRADEHEAESLGDVSVEAPGGTGAETLGGTGGPLLMLGRSDGNLVRWADGEEFIPLTDEKVVDTTGAGDALTAALTVGLLRGMPPVEAGRFAVAAAGATVGHPGGRPDLSRLRRG
>NC_017093.1|WP_014445899.1|6197410_6197761_-|nuclear-transport-factor-2-family-protein
MTDIDEAEINKARFLEAFGRFAQGDTAVLFEILREDFVSHTPGAPAGRDAWIEFIKGSPIATAEIEIQHVLAEDQLVVMHYFLTAGEVREAVVDLWRFEEGLIVEHWSVTEMLTPA
>NC_017093.1|WP_014445900.1|6198010_6198625_+|DUF4360-domain-containing-protein
MLNALTAGAMAVSSLTAPAAPPPTTEMVIDVVKTNGTGCPPGSAEVIVSPDNKAFTVSYSKFVAQVGPETAATDVRKNCQLLLNVLVPDGYTYAVAGVDYRGYANLQKGVTATESAFYYFQGESHTTEIKHELVGYLADEWQHSDRVPVESMSFLDCDNKRYLSVNTELKVDPANADRSVTNWVAMDSIDGDLETTYHVAWKRC
>NC_017093.1|WP_014445901.1|6198804_6199692_+|CDP-alcohol-phosphatidyltransferase-family-protein
MAQRPTLATIRERTYKRRDAWWTVWLVDPLASRLVWLVAPWRWVTPNRLTFGAFLVGLGSAACFWQQDYTWLLAGAVLYHLSFVLDCMDGKIARLNGTGSLFGTWLDYVFDRLRVLACAVGLFGGQYLRTEDAIYPVLATLVIFVDMFRYLNALQMSKVKLTMKDRLLAAAVAAGTTNPTYVEESDEAAPAYPDADPAQAAVDVHGDFRTRFGLFVRIRNFLLRQRIRAHVFSGIEFMMFVFIIGPVIGQIVVTTVVSSVLLLAFEALLVFKLWTTTKTFNRRLAKLENSAPALV
>NC_017093.1|WP_014445902.1|6199882_6202114_+|alpha-amylase
MRTRSRSLLVGSLTALTAAAGILTAVTLPTTASAAVTLNNSDVTANLWQWNFDSVAAACTDHLGPAGYGAVQVAPPQDSVSLSSSSDGAHPWWEVYQPTSYEIAGRLGNRTDFTDMVTACHNAGVRVYVDAVVNHMAGANNTQTTTYGGSTFSPSGYSYPSVPYSYNDFHHPNDGYCNDEDGVIDNWNDINEITNCELLSLSDLKTQDSSVRTKIAGFLNKLIGYGVDGFRIDAAKHVSIGDFSAIRGQLATTTAEGKAPYIAQEIFPGGVSPSSYTPNGDVLGFSYAYGLKSQFANGTLSNLAGIGSWSLDASSALTAAMVTNHDLERDGSTLRYQDGSPYVLANYFLLAYPYGQPFVYDGFAFSTSATGASPPSDSRGFVTGTNCANGAWQCLTQSTGVKGMVGWRNATQSVSTVSNWTGTASNVIGFSRGNLGWFGVNRSGSASTATYRTGLADGAYCDRITGGVTSGGTCAGTSITVSGGTASITIPANGAVAVDVNAKRGTTASPSASASASPSTSVSPSVSVSPSVSVSPSASVSPSASAGTGTVAATFNVYATTTTGTDVYVVGSNAALGSWNTANAVKLSATGYPVWSSTVAVPSGTSFEYKYIKKDASGTVTWESTANRAASTGTSPVTFTNSWNVANATTVTFTETATTSAGQNVYVVGSIDSLGAWNPANAIPLAATSYPAWSRPVAVPQNTTFQYKYIKKDASGTVTWESGSNRSYTTGTSTTYTTTDTWK

Crispr_ID: NC_017093_20

• CRISPR_ID: NC_017093_20
• CRISPR_location: 6560987-6562312
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 22 spacers

Consensus repeat of NC_017093_20

Consensus_repeat	Method
CGGTNNCCNCCACGGNNN	CRT

spacers of NC_017093_20

>20.1|6561005|33|NC_017093|CRT
TAACCACCACGGTTGCCACCCTGGTAGCCCCCG
>20.2|6561056|39|NC_017093|CRT
TAGCCGCCCCGGTCACGGTCGCCACCACGGAACCCGCCC
>20.3|6561113|27|NC_017093|CRT
TAGCCACCGCGGTCGCGGTCGCCACCA
>20.4|6561158|39|NC_017093|CRT
GGACGGTCACCCTGCGGACGGTCACTACGGAAGCCGCCG
>20.5|6561215|27|NC_017093|CRT
TAGCCACCGCGGTCGCGGTCTCCGCCA
>20.6|6561260|30|NC_017093|CRT
GGACGGTCACCCTGCGGACGGTCGCCACCA
>20.7|6561308|42|NC_017093|CRT
CCCTGGAAGCCCTCACGCGGACCACTCGGACGGTCCCCGCCA
>20.8|6561368|39|NC_017093|CRT
CCGCCACCCTGGTAACCGCCACGGTCACGGTCCCCGCCA
>20.9|6561425|45|NC_017093|CRT
CCGCCACCCTGGTAGCCGCCCCGGTCACCCTGCGGCCGGTCACTG
>20.10|6561488|27|NC_017093|CRT
CCGCCACCCTGGTAGCCACCGCGATCG
>20.11|6561533|66|NC_017093|CRT
CCGCCACCCTGCGGACGGTCACCCTGCGGACGGTCACTACGGAAACCACCGCGGTCGCCCTGCGGA
>20.12|6561617|39|NC_017093|CRT
CCACCGCGGTCGCCGCCACCCTGGTAACCGCCACGGTCA
>20.13|6561674|66|NC_017093|CRT
CCGCCACCCTGCGGACGGTCACCCTGCGGACGGTCACTACGGAAACCACCGCGGTCGCCCTGCGGA
>20.14|6561758|39|NC_017093|CRT
CCACCGCGGTCGCCGCCACCCTGGAAACCACCACGGTCA
>20.15|6561815|39|NC_017093|CRT
CCACTGCGGTCGCCGCCACCCTGGTAACCGCCACGGTCA
>20.16|6561872|69|NC_017093|CRT
CCGCCCCCCTGCGGACGGTCACTACGGAAACCACCCCGGTCGCCGCCACCCTGATAGCCGCCCCGGTCA
>20.17|6561959|39|NC_017093|CRT
CCACCGCGGTCGCCGCCACCCTGGTAACCGCCACGATCA
>20.18|6562016|39|NC_017093|CRT
CCACCGCGGTCGCCGCCACCCTGGTAGCCGCCACGATCA
>20.19|6562073|66|NC_017093|CRT
CCGCCACCCTGCGGACGGTCACCCTGCGGACGGTCACTACGGAAACCACCACGGTCGCCCTGCGGA
>20.20|6562157|39|NC_017093|CRT
CCGCCCCGGTCGCCGCCACCCTGGTAACCACCACGGTCA
>20.21|6562214|39|NC_017093|CRT
CCGCCCCGGTCGCCGCCACCCTGGTAACCACCGCGATCG
>20.22|6562271|24|NC_017093|CRT
CCGCCGCGGTCGCCGCTCACCGAG

CRISPR arrays and Neighbor proteins around NC_017093_20

CRISPR arrays

The CRISPR arrays of NC_017093_20

>merge|NC_017093|20|6560987-6562312|CRT
CGGTCGCCGCCACCCTGGTAACCACCACGGTTGCCACCCTGGTAGCCCCCGCGGTCGCCGCCACCCTGGTAGCCGCCCCGGTCACGGTCGCCACCACGGAACCCGCCCCGGTCGCCGCCACCCTGGTAGCCACCGCGGTCGCGGTCGCCACCACGGAAGCCGCCACCCTGCGGACGGTCACCCTGCGGACGGTCACTACGGAAGCCGCCGCGGTCGCCGCCACCCTGGTAGCCACCGCGGTCGCGGTCTCCGCCACGGAAGCCGCCGCCCTGCGGACGGTCACCCTGCGGACGGTCGCCACCACGGAACCCGCCGCGGTCGCCCTGGAAGCCCTCACGCGGACCACTCGGACGGTCCCCGCCACGGAAGCCGCCGCGGTCGCCGCCACCCTGGTAACCGCCACGGTCACGGTCCCCGCCACGGAACCCGCCGCGGTCGCCGCCACCCTGGTAGCCGCCCCGGTCACCCTGCGGCCGGTCACTGCGGAAACCGCCGCGGTCGCCGCCACCCTGGTAGCCACCGCGATCGCGGTCTCCGCCACGGAAGCCGCCACCCTGCGGACGGTCACCCTGCGGACGGTCACTACGGAAACCACCGCGGTCGCCCTGCGGACGGTCCCCACCACGGAAACCACCGCGGTCGCCGCCACCCTGGTAACCGCCACGGTCACGGTCTCCGCCACGGAAGCCGCCACCCTGCGGACGGTCACCCTGCGGACGGTCACTACGGAAACCACCGCGGTCGCCCTGCGGACGGTCCCCACCACGGAAACCACCGCGGTCGCCGCCACCCTGGAAACCACCACGGTCACGGTCGCCACCACGGAAACCACTGCGGTCGCCGCCACCCTGGTAACCGCCACGGTCACGGTCGCCACCACGGAAGCCGCCCCCCTGCGGACGGTCACTACGGAAACCACCCCGGTCGCCGCCACCCTGATAGCCGCCCCGGTCACGGTCGCCACCACGGAAACCACCGCGGTCGCCGCCACCCTGGTAACCGCCACGATCACGGTCGCCACCACGGAAACCACCGCGGTCGCCGCCACCCTGGTAGCCGCCACGATCACGGTCGCCACCACGGAAGCCGCCACCCTGCGGACGGTCACCCTGCGGACGGTCACTACGGAAACCACCACGGTCGCCCTGCGGACGGTCCCCACCACGGAAACCGCCCCGGTCGCCGCCACCCTGGTAACCACCACGGTCACGGTCACCGCCACGGAACCCGCCCCGGTCGCCGCCACCCTGGTAACCACCGCGATCGCGGTCGCCACCACGGAAGCCGCCGCGGTCGCCGCTCACCGAGCGCTGGCCACCCTGGTAG

>NC_017093|20|1|6560987-6562312|CRT
CGGTCGCCGCCACCCTGG	TAACCACCACGGTTGCCACCCTGGTAGCCCCCG
CGGTCGCCGCCACCCTGG	TAGCCGCCCCGGTCACGGTCGCCACCACGGAACCCGCCC
CGGTCGCCGCCACCCTGG	TAGCCACCGCGGTCGCGGTCGCCACCA
CGGAAGCCGCCACCCTGC	GGACGGTCACCCTGCGGACGGTCACTACGGAAGCCGCCG
CGGTCGCCGCCACCCTGG	TAGCCACCGCGGTCGCGGTCTCCGCCA
CGGAAGCCGCCGCCCTGC	GGACGGTCACCCTGCGGACGGTCGCCACCA
CGGAACCCGCCGCGGTCG	CCCTGGAAGCCCTCACGCGGACCACTCGGACGGTCCCCGCCA
CGGAAGCCGCCGCGGTCG	CCGCCACCCTGGTAACCGCCACGGTCACGGTCCCCGCCA
CGGAACCCGCCGCGGTCG	CCGCCACCCTGGTAGCCGCCCCGGTCACCCTGCGGCCGGTCACTG
CGGAAACCGCCGCGGTCG	CCGCCACCCTGGTAGCCACCGCGATCG
CGGTCTCCGCCACGGAAG	CCGCCACCCTGCGGACGGTCACCCTGCGGACGGTCACTACGGAAACCACCGCGGTCGCCCTGCGGA
CGGTCCCCACCACGGAAA	CCACCGCGGTCGCCGCCACCCTGGTAACCGCCACGGTCA
CGGTCTCCGCCACGGAAG	CCGCCACCCTGCGGACGGTCACCCTGCGGACGGTCACTACGGAAACCACCGCGGTCGCCCTGCGGA
CGGTCCCCACCACGGAAA	CCACCGCGGTCGCCGCCACCCTGGAAACCACCACGGTCA
CGGTCGCCACCACGGAAA	CCACTGCGGTCGCCGCCACCCTGGTAACCGCCACGGTCA
CGGTCGCCACCACGGAAG	CCGCCCCCCTGCGGACGGTCACTACGGAAACCACCCCGGTCGCCGCCACCCTGATAGCCGCCCCGGTCA
CGGTCGCCACCACGGAAA	CCACCGCGGTCGCCGCCACCCTGGTAACCGCCACGATCA
CGGTCGCCACCACGGAAA	CCACCGCGGTCGCCGCCACCCTGGTAGCCGCCACGATCA
CGGTCGCCACCACGGAAG	CCGCCACCCTGCGGACGGTCACCCTGCGGACGGTCACTACGGAAACCACCACGGTCGCCCTGCGGA
CGGTCCCCACCACGGAAA	CCGCCCCGGTCGCCGCCACCCTGGTAACCACCACGGTCA
CGGTCACCGCCACGGAAC	CCGCCCCGGTCGCCGCCACCCTGGTAACCACCGCGATCG
CGGTCGCCACCACGGAAG	CCGCCGCGGTCGCCGCTCACCGAG
CGCTGGCCACCCTGGTAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_014446208.1|6556765_6557101_+|SCP2-sterol-binding-domain-containing-protein	unknown	unknown	gnl|CDD|376720
NC_017093.1|WP_014446219.1|6572472_6573513_-|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl|CDD|176197
NC_017093.1|WP_041831445.1|6575659_6576622_-|1-phosphofructokinase-family-hexose-kinase	unknown	unknown	gnl|CDD|274464
NC_017093.1|WP_014446205.1|6554609_6555425_-|TlyA-family-RNA-methyltransferase	unknown	unknown	gnl|CDD|224110
NC_017093.1|WP_014446211.1|6558853_6559858_-|HAD-IIA-family-hydrolase	unknown	unknown	gnl|CDD|319832
NC_017093.1|WP_014446218.1|6572144_6572420_-|HPr-family-phosphocarrier-protein	unknown	unknown	gnl|CDD|376329
NC_017093.1|WP_014446215.1|6568402_6569659_-|tyrosine--tRNA-ligase	unknown	unknown	gnl|CDD|235645
NC_017093.1|WP_041830152.1|6570499_6572152_-|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl|CDD|224006
NC_017093.1|WP_014446212.1|6559854_6560805_-|hypothetical-protein	unknown	unknown	gnl|CDD|367841
NC_017093.1|WP_014446224.1|6576672_6577434_-|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl|CDD|224268
NC_017093.1|WP_041830151.1|6550665_6551844_-|hypothetical-protein	unknown	unknown	gnl|CDD|227162
NC_017093.1|WP_172666634.1|6557146_6558430_-|chemotaxis-protein	unknown	unknown	gnl|CDD|206779
NC_017093.1|WP_014446210.1|6558588_6558834_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014446216.1|6569720_6570503_+|UDP-galactose-lipid-carrier-transferase	unknown	unknown	gnl|CDD|274736
NC_017093.1|WP_014446225.1|6578200_6578776_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_041830153.1|6573945_6574254_-|PTS-lactose-transporter-subunit-IIB	unknown	unknown	gnl|CDD|99909
NC_017093.1|WP_014446220.1|6573509_6573953_-|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl|CDD|236849
NC_017093.1|WP_014446204.1|6553725_6554613_-|NAD-kinase	unknown	unknown	gnl|CDD|235121
NC_017093.1|WP_014446206.1|6555450_6555642_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014446203.1|6551917_6553675_-|DNA-repair-protein-RecN	unknown	unknown	gnl|CDD|223571

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_014446208.1|6556765_6557101_+|SCP2-sterol-binding-domain-containing-protein	gnl|CDD|376720	pfam02036, SCP2, SCP-2 sterol transfer family. This domain is involved in binding sterols. It is found in the SCP2 protein, as well as the C-terminus of the enzyme estradiol 17 beta-dehydrogenase EC:1.1.1.62. The UNC-24 protein contains an SPFH domain pfam01145.	2.80167e-09
NC_017093.1|WP_014446219.1|6572472_6573513_-|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl|CDD|176197	cd08235, iditol_2_DH_like, L-iditol 2-dehydrogenase. Putative L-iditol 2-dehydrogenase based on annotation of some members in this subgroup. L-iditol 2-dehydrogenase catalyzes the NAD+-dependent conversion of L-iditol to L-sorbose in fructose and mannose metabolism. This enzyme is related to sorbitol dehydrogenase, alcohol dehydrogenase, and other medium chain dehydrogenase/reductases. The zinc-dependent alcohol dehydrogenase (ADH-Zn)-like family of proteins is a diverse group of proteins related to the first identified member, class I mammalian ADH. This group is also called the medium chain dehydrogenases/reductase family (MDR) to highlight its broad range of activities and to distinguish from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal GroES-like catalytic domain. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	6.2228e-174
NC_017093.1|WP_041831445.1|6575659_6576622_-|1-phosphofructokinase-family-hexose-kinase	gnl|CDD|274464	TIGR03168, 1-PFK, hexose kinase, 1-phosphofructokinase family. This family consists largely of 1-phosphofructokinases, but also includes tagatose-6-kinases and 6-phosphofructokinases.	7.36417e-99
NC_017093.1|WP_014446205.1|6554609_6555425_-|TlyA-family-RNA-methyltransferase	gnl|CDD|224110	COG1189, COG1189, Predicted rRNA methylase [Translation, ribosomal structure and biogenesis].	1.83193e-103
NC_017093.1|WP_014446211.1|6558853_6559858_-|HAD-IIA-family-hydrolase	gnl|CDD|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.05149e-83
NC_017093.1|WP_014446218.1|6572144_6572420_-|HPr-family-phosphocarrier-protein	gnl|CDD|376329	pfam00381, PTS-HPr, PTS HPr component phosphorylation site.	2.71401e-24
NC_017093.1|WP_014446215.1|6568402_6569659_-|tyrosine--tRNA-ligase	gnl|CDD|235645	PRK05912, PRK05912, tyrosyl-tRNA synthetase; Validated.	0
NC_017093.1|WP_041830152.1|6570499_6572152_-|phosphoenolpyruvate--protein-phosphotransferase	gnl|CDD|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	2.718e-169
NC_017093.1|WP_014446212.1|6559854_6560805_-|hypothetical-protein	gnl|CDD|367841	pfam04147, Nop14, Nop14-like family. Emg1 and Nop14 are novel proteins whose interaction is required for the maturation of the 18S rRNA and for 40S ribosome production.	1.2023e-06
NC_017093.1|WP_014446224.1|6576672_6577434_-|DeoR/GlpR-transcriptional-regulator	gnl|CDD|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	3.07721e-82
NC_017093.1|WP_041830151.1|6550665_6551844_-|hypothetical-protein	gnl|CDD|227162	COG4825, COG4825, Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown].	2.78589e-129
NC_017093.1|WP_172666634.1|6557146_6558430_-|chemotaxis-protein	gnl|CDD|206779	cd11386, MCP_signal, Methyl-accepting chemotaxis protein (MCP), signaling domain. Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.	6.63541e-32
NC_017093.1|WP_014446216.1|6569720_6570503_+|UDP-galactose-lipid-carrier-transferase	gnl|CDD|274736	TIGR03708, poly_P_AMP_trns, polyphosphate:AMP phosphotransferase. Members of this protein family contain a domain duplication. The characterized member from Acinetobacter johnsonii is polyphosphate:AMP phosphotransferase (PAP), which can transfer the terminal phosphate from poly(P) to AMP, yielding ADP. In the opposite direction, this enzyme can synthesize poly(P). Each domain of this protein family is homologous to polyphosphate kinase, an enzyme that can run in the forward direction to extend a polyphosphate chain with a new terminal phosphate from ATP, or in reverse to make ATP (or GTP) from ADP (or GDP). [Central intermediary metabolism, Phosphorus compounds].	2.12629e-92
NC_017093.1|WP_041830153.1|6573945_6574254_-|PTS-lactose-transporter-subunit-IIB	gnl|CDD|99909	cd05567, PTS_IIB_mannitol, PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain. The IIA, IIB, and IIC domains are expressed from the mtlA gene as a single protein, also known as the mannitol PTS permease, the mtl transporter, or MtlA. MtlA is only functional as a dimer with the dimer contacts occuring between the IIC domains. MtlA takes up exogenous mannitol releasing the phosphate ester into the cytoplasm in preparation for oxidation to fructose-6-phosphate by the NAD-dependent mannitol-P dehydrogenase (MtlD). The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include mannitol, chitobiose/lichenan, ascorbate, lactose, galactitol, fructose, and a sensory system with similarity to the bacterial bgl system.	4.99803e-24
NC_017093.1|WP_014446220.1|6573509_6573953_-|PTS-sugar-transporter-subunit-IIA	gnl|CDD|236849	PRK11109, PRK11109, fused PTS fructose transporter subunit IIA/HPr protein.	1.18509e-39
NC_017093.1|WP_014446204.1|6553725_6554613_-|NAD-kinase	gnl|CDD|235121	PRK03372, ppnK, inorganic polyphosphate/ATP-NAD kinase; Provisional.	4.86814e-152
NC_017093.1|WP_014446203.1|6551917_6553675_-|DNA-repair-protein-RecN	gnl|CDD|223571	COG0497, RecN, ATPase involved in DNA repair [DNA replication, recombination, and repair].	0

Protein sequences

>NC_017093.1|WP_014446212.1|6559854_6560805_-|hypothetical-protein
MADKVARHLVAAGQIIDEDSELALQHAIAARRLASRIAVVREAVGLAAYAAGDWTTAIAELRTYHRMTGRQTHLAELADCERALGRPERAIDLYRGADMAKLEKSGAIELLIVAAGARSDLGQHDAAVAMLQVNELTSQEDADWAARLRYAYADALLAAGRREEAREWFARAAAVDTEQLTDAAERLLELDGVAIEGDDDEDDEETEAALGEGGAETRSEDDDDSEGDTAEFDGEDDEPVAVRDADEFDDEDDEDEPVAARTADSAEFADEDDEDDESAELSATDVNTDGLADADEKHADEKHADEKHADDEQPRG
>NC_017093.1|WP_014446211.1|6558853_6559858_-|HAD-IIA-family-hydrolase
MSDHLAAGYDLVIFDLDGVVFLIDKPIPGAAEAVDRLRSGGTPIAYATNNASRRAADVATLLTGMGVSATPAEVLTSAGAAAALLAERFPAGAPVLVVGAEALRAEVRDAGLTPVGSAEDEPVAVVQGYGPEVGWKVLSEAALAVRAGAAWFATNTDRTLPSPRGPLPGNGSLVAVLRTALDREPDVVVGKPQPGLFTTAATLSRADRPLAVGDRLDTDIQGAVGAGMDSLLVLTGVSGPADLLAAPAERRPAFVAADLSGLFRPADEARVPATGGEAGGWRVSRDGDRAVLDGSGDPVDALRLLCGVTWDGVPVAAVEAGSPAAGELLRDWGV
>NC_017093.1|WP_014446210.1|6558588_6558834_+|hypothetical-protein
MTSSDDLHTQAESVAVPSFDWMSTPVLSVVDGLLHIDPDAPLPRRRYRPAASVAPEHAPTDSATIESSRLLAGLTRHHPRH
>NC_017093.1|WP_172666634.1|6557146_6558430_-|chemotaxis-protein
MSGFTLPRGARLSDASWAARHRIVTRLLWFHAPVFFVVGILGPRPTWEAILLPVLVGVWAAAATLVPSSSGKSSHTSVGLIACTFVAIELTGGEMSAHIHLYAVLIFVALYQQWTPLASSIAVVVVHHGVLGLIAPDRVFGDHHMGVAAALVMVAVHAGLLTLEVAGIVIFWHFAEQAERENEALAQQAEQARRDVERAEQESRERAAEDLRIRSEQTAEQARQITADVAGISGEAHAAISAVASVDRELAALTASVGDIARRSAAAAETAAGGKEAASSAGEKVRALERSVAEIAEVNALIASLAEQTNLLALNATIEAARAGELGKGFAVVAGEVKDLARETATSVERVKQVITAIVAETDDVAQTFASTTGAVDEIHKVQLNIAASVEEQALMLAEVTTQLSNATSAADQVLAGLQTLSARAGS
>NC_017093.1|WP_014446208.1|6556765_6557101_+|SCP2-sterol-binding-domain-containing-protein
MATVDECRQALHDLAAKLAANAEAQGHLDLDRTLACRITDLDTAFHGRITGGRLIDIADGDDPKAKIALTATSDHLIELINGKLDLTRAFTSGQIKVKANPFDLLKLRKLL
>NC_017093.1|WP_014446206.1|6555450_6555642_-|hypothetical-protein
MTFPNAAQPAPPLGGNPEDTGHPAVDAVLRSLANAARLAPAEQIAEYEAAHQVLQETLASIDR
>NC_017093.1|WP_014446205.1|6554609_6555425_-|TlyA-family-RNA-methyltransferase
MARRARLDAELVRRKLARSREQAATLVEAGRVQVRGVVAHKVAAMVDPADPVLVTGEDPQTEYVSRGGHKLAGALSAFGGGGLTVDGRRCLDAGASTGGFTDVLLRAGAREVVAVDVGYGQLAWPIRQNERVVVMERTNVRTLTPDAIGGPVDLTVADLSFISLRLVLPALAACTDGDLALMVKPQFEVGKERVGAGGVVRDWRLRAEAVLDVAAAAQELGLGVRDVTASPLPGPSGNVEFFVWFRRDAPPADRERVESVVEAGPVPLEEK
>NC_017093.1|WP_014446204.1|6553725_6554613_-|NAD-kinase
MTRSALLVTHTGRRQSTQHARAVALDLIAAGFEVRVIAEEVADLDLPDEVKPVDGPGAAEGVEIVLALGGDGTFLRAADLARPVKAPLLGINLGKVGFLAEAEIEHIDEAVASVVAGDYTVDERLTLDVRAEYDGRLIAESWALNEVSVEKGQRAQMLELLVDVDGRPLSRYGCDGVVCATPTGSTAYAFSAGGPVVWPEVEALLLVPISAHALFSKPLVTAPTSTFVLTVDPYTSFAVLCCDGRRTWDLPPGSKVTVERGQLPVRVVRLAPRPFTDTLVAKFELPVVGWRGNRR
>NC_017093.1|WP_014446203.1|6551917_6553675_-|DNA-repair-protein-RecN
MLEELRITGLGVIDDTTLRLTSGMNVITGETGAGKTMVVTGLGLLFGGRADAGRVRADPGRAVVEGRLNLRGTLGDAVRTRITDAGGETDDDGSLLLSRTVTAEGRSRAHVGGRSMPVSTLSELGEQVLAVHGQSDQLRLLRPSEQRSALDRFAGPGHEKLLDSYREAFTRWRRVVDDLTDRRRNARQRSQEADLLKLGLDEITRVDPQPGEDEDLRAEVQRLEHAEGLRVAAAQAAQALAGGVEAADDTPDATQLLGTARRTLEGQAGVDPALGDLAARIEEAATLVGDVSSELSAYLGTLDADPARLEAIYERRAALRALTRKYADDIDGVITWAENARAKLSELDTSDELLEEMDKERQRLAATVGELAGRLTAARREAAGRFSEAVSVELAGLAMPHARVEVAVVTRSPSRDEPSVTVDGEELAAGADGADEVELRLLAHPGAPSLPLQKGASGGELSRVMLAIEVVFAGAGGPPTLVFDEVDSGVGGTAAVEIGRRLARLARTHQVLVVTHLPQVAAFADRHLVVAKDTGGAITTSGVRIVEETERARELSRMLAGLPDSDLGIAHAEELLSVAAREKRA
>NC_017093.1|WP_041830151.1|6550665_6551844_-|hypothetical-protein
MRLPTLRRTRATEPGPVSGLVRLDRRTKRLTGRLRPGEIAVIDHIDLDRVAADSLVASGVTAVLNAKPSISGRYPNLGPEVLIQGGVVLVDGLGEDVFKGLREGQTVSIDGGTVLLGGEPVATGVRQDAESVAQSMADAREGLSVQLEAFAANTLDYMKQERELLLDGVGVPDVRTRIAGRHVLIVVRGYDYKEDLDVLRPYIREYKPVLIGVDGGADALVENGYTPDMIIGDMDSVTDDVLRCGAEVIVHAYPDGRAPGLERVRGVGVDAITFPAAATSEDLAMLLADEKGASLIVAVGTHANLVEFLDKGRGGMASTFLTRLKVGGKLVDAKGVSRLYRQNISGSALLLLVLSAMAAMASAVAVSTVGKAYLTVVSEWWDNFVFQLGNLF
>NC_017093.1|WP_014446215.1|6568402_6569659_-|tyrosine--tRNA-ligase
MTLVDDLLWRGLIQDSTDPDELRKALDGGSIPFYVGFDPTAASLHVGHLMQVLTARRLQQGGHRPLLLVGGATGQIGDPRESSERSLNPPEVVQGWVERIRTQLSPFVTYQGDNAATLVNNLDWTGPTSVIEFLRDVGKHFPVNKMLARDVVRNRLESGISFTEFSYQLLQSNDFYQLHVQHGCRLQFGGSDQWGNITAGVDFVRRRGAGPVHAFVTPLVLKADGTKFGKTEGGAIWLDPAMTSPYSFYQFWINSDDRDVSKYLRYFSFKSREELEELEKATAERPQARLAQRALAFEITALVHGEEEANQAVAASQALFGRGSLDELSADTLRAALAEAGLHPVRGELPAVGTLLKESGLVASANEARRTITEGGAYLNNERITDGEAVVPESALLHGRFLVLRRGKRTFAGVEIVK
>NC_017093.1|WP_014446216.1|6569720_6570503_+|UDP-galactose-lipid-carrier-transferase
MGHLGSAAAPIDISKKKAEERLEAAQERLLRLRLLLGGQIGEKKIGPPLCVLFEGWDASGKGGAIKRLVTMIDPRHVRVSQFAAPTYDEKRHHFLQRFWQVLPGNGGMTVLDRSWYGRVLVERVEGFATTEQWQRAYDEIAEFERTLAAEGMILIKFWMHVSEEEQLRRFEDRANDPLRSWKLTDEDWRNRKKRPEYEAAIEDMLEKTDRPRARWKVIPGDSKPYARLAVVEHVCHVLERKLAKRGYDLASADRPGTASV
>NC_017093.1|WP_041830152.1|6570499_6572152_-|phosphoenolpyruvate--protein-phosphotransferase
MAEVVSLSGIGVCAGVAAGPLLRIADVPALPPMVAVTDAEAEVARASSALAEVVTFLERRADRATDETVAEVLRAEAMMAGDEALLDGVREHVEEGADAVHAVSLAFGAFRESFEAAGGYLAERVADLDDLRNRAVAVLLGQPMPGIPQPGHPFVLAAKDLAPADTADLDPAQVLALVTEVGGPTSHTAILARALGLPAVVSCPGVLAIAEGTLVLVDGATGRVDAGIDQVAAEAAVRGAAEVAAAAAALTGPGQTSDGYGVKLLANVGSAKNVPAADEVHAEGVGLFRTELLFLDRTREPGLDEQVEAYREVFSAMAGRRVVIRTLDAGADKPLPFLNQEGEPNPALGVRGLRIARQRPDVLTTQLAAIAEARAQTGADVWVMAPMVSTITEAATFAAAVHEAGLPRAGVMIEVPAAALRARDLLGVVDFLSIGTNDLSQYTFAADRMCGALADLLDPWQPALLQLIGICGEAGRAAGKPVGVCGEAAADAALAPILVGLGVTSLSMSPRALPAVRAALAGVTEADCRRLAELAVAAPDAATARKAAIG
>NC_017093.1|WP_014446218.1|6572144_6572420_-|HPr-family-phosphocarrier-protein
MPTRTVAVGSASGLHARPAKIFVEAAAAAPVKVTIRVGDKKPVPAKSMLSVLALGAKQGTEVTLEAEGDGAEQTLSDLAALLATDLDASDG
>NC_017093.1|WP_014446219.1|6572472_6573513_-|alcohol-dehydrogenase-catalytic-domain-containing-protein
MKVVRFHAPGDVRFEDVPEPEAGPGEVKIRVRNCSTCGTDVKISKFGHHHIHPPRVMGHEIAGEVVAVGDGVEGWQPGDRVQVIAAIPCGECAECRRGRMTVCPNQVSMGYHFEGGFAQFMVVPTEVLKVDGLNRIPDGVSFAEASVAEPLACALNAQNLARVGEGDDVVVIGSGPIGCLHVRLARARGAARVFLVELNRERLDMAANLVKPDAAICAGEVDPVEEVRKLTDGRGADVIITAAASGKAQEQAIEMAARQGRISFFGGLPKDNPTITCDSNLVHYRELMIIGANGSSPSHNKEALQLVATGAVPVADLITHRLPLEGAIDAFGIVARGEAIKVTIEP
>NC_017093.1|WP_014446220.1|6573509_6573953_-|PTS-sugar-transporter-subunit-IIA
MSELLDRRAIRLDEKAGSKEDAIRLTGAALVEIGAVEPGYVDTMLAREKSISTYVGEGVAIPHGTLDGKALVKRDALAVLRFPAGVDWDGERVSVCVGIAAAGDGHVELLAALAEILLDADDARALREAAEADTVINLLGRIEGNPE
>NC_017093.1|WP_041830153.1|6573945_6574254_-|PTS-lactose-transporter-subunit-IIB
MATINGKDIRKLIVACDAGMGSSVMLASTLRKQLGKNGVTVEHSPVNSIPADADLVVCHSGLAARARSVAPDKPIVPFQIFLGDPAVTKVVKAIQQGTDLNV
>NC_017093.1|WP_041831445.1|6575659_6576622_-|1-phosphofructokinase-family-hexose-kinase
MTGLNPGTVLTVTLNPSVDRALEVDALVRGEVLRAADSHIDPGGKGVNVSRALLANGIRSTAVVPAGGAEGEQLVDLLKGEGVDMLAVPITGRTRSNITLAEPDGTVTKINEAGPTLSDTEFAQVSDAVLAAAGTADWVVICGSLPPGPTVAAFTDLCERLVKSGVRLAVDSSGPALLAGVAAGAALVKPNREELAEATGTDLVTLGDVIRACGRLREAGAGTVLASLGAEGAVLVDAAGVITGVSPVSVPRSTVGAGDALLAGFLAAGASGEAALVEGLAWGAAAVSLPGSRMPKPQDLDRTSIRLDREPDLNRPLRRD
>NC_017093.1|WP_014446224.1|6576672_6577434_-|DeoR/GlpR-transcriptional-regulator
MYAEERQQEIVQRARAEGRVDVVALADTFGVTAETIRRDLTVLERAGVLRRVHGGAIPVERLGFEPALATRDAVLISEKERIAKAALAEVPEDGAIILDAGTTTARLAQLLPADRELTVVVNSPVLASTLGLKPNLTVLLLGGRVRGKTLATVDDWALRPLADMYVDVAFMGTNGCTVERGMTTPDPAEAAVKRAMIAAARRVVLLADHTKIGNDYLARFGGLADLDLLITDNGLDGELAAEVEVAGVRLVRA
>NC_017093.1|WP_014446225.1|6578200_6578776_-|hypothetical-protein
MTITVDQLTGYVSRDLDADLARWFPGAEPAEVGADARPVEPFLPRLPAAAASALAALDQRVRAGGIPVDLDILDFSYGFDFAANECGILDSDYETPLTGDDVHAIAADGSGNLHVLLTNGQVAVWFHEEEVLEAETRFDNLDVFLWSLVRYRAVLAGTLRLSEVEADFEALAQDGVLAPELGMLTVMRARA

Crispr_ID: NC_017093_21

• CRISPR_ID: NC_017093_21
• CRISPR_location: 6610596-6610681
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_21

Consensus_repeat	Method
TGTTGACTTCGGGTTCGTTCCGCAC	CRISPRCasFinder

spacers of NC_017093_21

>21.1|6610621|36|NC_017093|CRISPRCasFinder
CCCCCTTCCACACACAGGGTCGGCCCACCCGGAGCG

CRISPR arrays and Neighbor proteins around NC_017093_21

CRISPR arrays

The CRISPR arrays of NC_017093_21

>merge|NC_017093|21|6610596-6610681|CRISPRCasFinder
TGTTGACTTCGGGTTCGTTCCGCACCCCCCTTCCACACACAGGGTCGGCCCACCCGGAGCGTGTTGACTTCGTGTTCGTTCCGCAC

>NC_017093|21|20|6610596-6610681|CRISPRCasFinder
TGTTGACTTCGGGTTCGTTCCGCAC	CCCCCTTCCACACACAGGGTCGGCCCACCCGGAGCG
TGTTGACTTCGTGTTCGTTCCGCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_014446244.1|6592400_6593321_+|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl|CDD|376667
NC_017093.1|WP_014446245.1|6593329_6595741_+|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|238923
NC_017093.1|WP_014446260.1|6616208_6616706_-|arginine-repressor	unknown	unknown	gnl|CDD|235116
NC_017093.1|WP_014446258.1|6614080_6615319_-|argininosuccinate-synthase	unknown	unknown	gnl|CDD|238957
NC_017093.1|WP_014446253.1|6607651_6608908_-|maltose-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270304
NC_017093.1|WP_014446257.1|6612961_6614020_+|succinyl-diaminopimelate-desuccinylase	unknown	unknown	gnl|CDD|237264
NC_017093.1|WP_014446259.1|6615315_6616209_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014446263.1|6618782_6619694_-|acetylglutamate-kinase	unknown	unknown	gnl|CDD|234869
NC_017093.1|WP_014446265.1|6620859_6621861_-|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl|CDD|234761
NC_017093.1|WP_014446246.1|6595729_6596278_-|DinB-family-protein	unknown	unknown	gnl|CDD|378981
NC_017093.1|WP_014446264.1|6619690_6620863_-|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ	unknown	unknown	gnl|CDD|235441
NC_017093.1|WP_014446252.1|6606015_6607638_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|236816
NC_017093.1|WP_014446250.1|6603380_6605177_-|glycoside-hydrolase-family-13-protein	unknown	unknown	gnl|CDD|200477
NC_017093.1|WP_041831449.1|6597524_6597902_+|DUF1304-domain-containing-protein	unknown	unknown	gnl|CDD|377753
NC_017093.1|WP_014446251.1|6605173_6606019_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|226354
NC_017093.1|WP_157435482.1|6596446_6597130_+|FCD-domain-containing-protein	unknown	unknown	gnl|CDD|224715
NC_017093.1|WP_014446262.1|6617631_6618786_-|acetylornithine-transaminase	unknown	unknown	gnl|CDD|235112
NC_017093.1|WP_172666635.1|6611435_6612869_-|argininosuccinate-lyase	unknown	unknown	gnl|CDD|179143
NC_017093.1|WP_014446261.1|6616702_6617635_-|ornithine-carbamoyltransferase	unknown	unknown	gnl|CDD|234835
NC_017093.1|WP_014446249.1|6597971_6603380_-|pullulanase-type-alpha-1,6-glucosidase	unknown	unknown	gnl|CDD|273974

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_014446244.1|6592400_6593321_+|sulfite-exporter-TauE/SafE-family-protein	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	4.92246e-27
NC_017093.1|WP_014446245.1|6593329_6595741_+|EAL-domain-containing-protein	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	5.27319e-109
NC_017093.1|WP_014446260.1|6616208_6616706_-|arginine-repressor	gnl|CDD|235116	PRK03341, PRK03341, arginine repressor; Provisional.	1.58954e-63
NC_017093.1|WP_014446258.1|6614080_6615319_-|argininosuccinate-synthase	gnl|CDD|238957	cd01999, Argininosuccinate_Synthase, Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate . In humans, a defect in the AS gene causes citrullinemia, a genetic disease characterized by severe vomiting spells and mental retardation. AS is a homotetrameric enzyme of chains of about 400 amino-acid residues. An arginine seems to be important for the enzyme's catalytic mechanism. The sequences of AS from various prokaryotes, archaebacteria and eukaryotes show significant similarity.	2.93623e-120
NC_017093.1|WP_014446253.1|6607651_6608908_-|maltose-ABC-transporter-substrate-binding-protein	gnl|CDD|270304	cd13586, PBP2_Maltose_binding_like, The periplasmic-binding component of ABC transport systems specific for maltose and related polysaccharides; possess type 2 periplasmic binding fold. This subfamily represents the periplasmic binding component of ABC transport systems involved in uptake of polysaccharides including maltose, maltodextrin, and cyclodextrin. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.13753e-103
NC_017093.1|WP_014446257.1|6612961_6614020_+|succinyl-diaminopimelate-desuccinylase	gnl|CDD|237264	PRK13007, PRK13007, succinyl-diaminopimelate desuccinylase; Reviewed.	0
NC_017093.1|WP_014446263.1|6618782_6619694_-|acetylglutamate-kinase	gnl|CDD|234869	PRK00942, PRK00942, acetylglutamate kinase; Provisional.	3.33693e-157
NC_017093.1|WP_014446265.1|6620859_6621861_-|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl|CDD|234761	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated.	4.72698e-168
NC_017093.1|WP_014446246.1|6595729_6596278_-|DinB-family-protein	gnl|CDD|378981	pfam12867, DinB_2, DinB superfamily. The DinB family are an uncharacterized family of potential enzymes. The structure of these proteins is composed of a four helix bundle.	8.27255e-11
NC_017093.1|WP_014446264.1|6619690_6620863_-|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ	gnl|CDD|235441	PRK05388, argJ, bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ.	0
NC_017093.1|WP_014446252.1|6606015_6607638_-|ABC-transporter-permease-subunit	gnl|CDD|236816	PRK10999, malF, maltose ABC transporter permease MalF.	1.57126e-103
NC_017093.1|WP_014446250.1|6603380_6605177_-|glycoside-hydrolase-family-13-protein	gnl|CDD|200477	cd11338, AmyAc_CMD, Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins. Cyclomaltodextrinase (CDase; EC3.2.1.54), neopullulanase (NPase; EC 3.2.1.135), and maltogenic amylase (MA; EC 3.2.1.133) catalyze the hydrolysis of alpha-(1,4) glycosidic linkages on a number of substrates including cyclomaltodextrins (CDs), pullulan, and starch. These enzymes hydrolyze CDs and starch to maltose and pullulan to panose by cleavage of alpha-1,4 glycosidic bonds whereas alpha-amylases essentially lack activity on CDs and pullulan. They also catalyze transglycosylation of oligosaccharides to the C3-, C4- or C6-hydroxyl groups of various acceptor sugar molecules. Since these proteins are nearly indistinguishable from each other, they are referred to as cyclomaltodextrinases (CMDs). The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	1.69428e-145
NC_017093.1|WP_041831449.1|6597524_6597902_+|DUF1304-domain-containing-protein	gnl|CDD|377753	pfam06993, DUF1304, Protein of unknown function (DUF1304). This family consists of several hypothetical bacterial proteins of around 120 residues in length. The function of this family is unknown.	1.32768e-20
NC_017093.1|WP_014446251.1|6605173_6606019_-|sugar-ABC-transporter-permease	gnl|CDD|226354	COG3833, MalG, ABC-type maltose transport systems, permease component [Carbohydrate transport and metabolism].	1.1092e-88
NC_017093.1|WP_157435482.1|6596446_6597130_+|FCD-domain-containing-protein	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	1.84112e-41
NC_017093.1|WP_014446262.1|6617631_6618786_-|acetylornithine-transaminase	gnl|CDD|235112	PRK03244, argD, acetylornithine transaminase.	0
NC_017093.1|WP_172666635.1|6611435_6612869_-|argininosuccinate-lyase	gnl|CDD|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
NC_017093.1|WP_014446261.1|6616702_6617635_-|ornithine-carbamoyltransferase	gnl|CDD|234835	PRK00779, PRK00779, ornithine carbamoyltransferase; Provisional.	0
NC_017093.1|WP_014446249.1|6597971_6603380_-|pullulanase-type-alpha-1,6-glucosidase	gnl|CDD|273974	TIGR02103, pullulanase-like_protein_starch, alpha-1,6-glucosidases, pullulanase-type. Members of this protein family include secreted (or membrane-anchored) pullulanases of Gram-negative bacteria and pullulanase-type starch debranching enzymes of plants. Both enzymes hydrolyze alpha-1,6 glycosidic linkages. Pullulan is an unusual, industrially important polysaccharide in which short alpha-1,4 chains (maltotriose) are connected in alpha-1,6 linkages. Enzymes that cleave alpha-1,6 linkages in pullulan and release maltotriose are called pullulanases although pullulan itself may not be the natural substrate. This family is closely homologous to, but architecturally different from, the Gram-positive pullulanases of Gram-positive bacteria (TIGR02102). [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0

Protein sequences

>NC_017093.1|WP_014446253.1|6607651_6608908_-|maltose-ABC-transporter-substrate-binding-protein
MRIRTAGVIAVCAVALVGTAACGSNDSKDKASDTPSAAAASGELVIWADDKRSEALKPFAEKFGAENGVTVKVQAISKDQQTTFLTASQQGSGPDVMVGAHDWIGNLVQNGAIDPVQLSDEQKNGIAANAIKAITFNGQTYGVPYATENLGLIRNTELAPEAPATVEALVASGKKLKAEKKVSEILCLQVGQNGDAYHSYPFYSSAGGYLFGTNAAGDYDAKDLGVGKPESVEAFKKLGALGEKGDGALKRSITPENSIATFTGKKCAYLVSGPWAVTDVKKANLKYDISPVPGFEGGKEATPFLGVQTFYVAAKGKNKALAQEFVTNYVTTPELAVALYNAEPRPPALTAAFDQVKGADADLQKWADAGKNAVPLPAIPEMAAIWDPFGKAEAAVIGGADAEKTVTAAGKTISGSIK
>NC_017093.1|WP_014446252.1|6606015_6607638_-|ABC-transporter-permease-subunit
MTTKLGGPARRALPATEPSRHQKDESRQPKSGTSLTAQFVKILLLGLVTAFAVWAAFPLIAEEHWFGLALLVATTAAILYIYLTPRHIPAKYLVPGTLFLVVFQLFPVLYTASTAFTNFGDGHRGSKQDAIVAIQTSSVTRVPGSAEYALSIATQGDPATGPIVFLITDPATKAVSIGDAEGLTPAGAVTVTSSGKVTAAEGYTVLNAGQASARSKEITEFTVPTQGGAIRSAGLSRAYEGKAGRAYDAVTDSIRDMTSGKSWVADESVGAFVAADGERLAQGWKVNVGFDNFTRALTDDTISGPFLRTLIWNFAFALGSTGFTFVLGLFIALALHSSRVRGRNLYRILLVLPYAMPSFAMLLVWRDMFNTDFGLINNLFGTDVDWFGGAASARLAVILVQLWLGYPYMFLVSTGALQAIPGELLDATKVDGAGVWQSFTNVTLPLLMIPLTPLLISSFAFNFNNFNAIWLTTEGAPFPADNTTNGATDLLITYTYRLAFGGSGAQYGFAAAISIFIFLIVATISTISFRRTRQLEEVYS
>NC_017093.1|WP_014446251.1|6605173_6606019_-|sugar-ABC-transporter-permease
MTRWIKQVGWRHLVGLLGLVFALGPLLFVLSAAINPQGTLASSTLVPSGASAENFTKLFSDTNFGHWFLNSIVIAGVAAAASVFLSALAAYAFSRRRFHGHRIGLMSLLLIQMFPQFLAVVAIFLMFSTITDLWPAFGFNTWWGMILLYLGGALGVNTWLMKGFYDTIPKELDESAVVDGATHAEIFFKILLPLVAPILAVTGLLAFIGTMNEFLIANVFLTDSESKTLAVGLYGLVAGERDANFGVFCAGTLLTAIPTVGVFMYLQRYIVEGLSAGAVKG
>NC_017093.1|WP_014446250.1|6603380_6605177_-|glycoside-hydrolase-family-13-protein
MIPHHDGSALYVSNPAPALGETVAVFVRAPAGTRISRIHTRFVRDGEPVFTSAVVDRRDASGEWWRAEVEVRNPITPYRFLIRTATGAVRWLTAGGLTSYDVPDATDFRLVAHPPAPDWSRDAIVYQIFPDRFARSAAADGRPTPDWAVRCDWDTPVEGRGPLAATQLYGGDLDGIAEHLDHVADLGANTLYLTPFFPSRSNHRYDGADFGTVDPLLGGDTALVRLTEAVHARGMRVIGDLTTNHTGDTHEWFRSEKDFYYVDDDGGYESWLGVPSLPKLNWGSPELRRRFAKLAQHWLTYPYALDGWRIDVANMTGRRGADDWTREVAALLARAVRQVRPDAMLLAEHGHDATGDLDADGWQGTMNYAGFTRPVWSWLRDDEVPFPDFLGVPEEIPLRDAADLVSTMTAFAARTSWRSRVASWQILSSHDTPRIRSVVGGPERHEVAAGLLFTLPGTPMIFAGDELGLTGYNGEHSRTPMPWNDTGGWDMRTLARHRALARLRGGTPALRDGGLRWLHATGDLLVFLRETAADTVLVVARRAPGLPVRVTGLVPHAWGDNLYGGAEALKSGADGSIEIDGDGPTFQVWSVRQHPKGC
>NC_017093.1|WP_014446249.1|6597971_6603380_-|pullulanase-type-alpha-1,6-glucosidase
MAPRKRRLGVALLSLLLPLIAVPAAASAATPAAPEPSAAVIANWGSDQRTDSEQYYFVLPDRFANGEKSNDRGGLGGDRLSTGYDPADKGFYHGGDLKGVIDRLDYIQGLGTTAIWLAPVFKNNPVQGTGADVSAGYHGYWITDFTQVDPHFGTNADLKKLVKLAHQRGMKIFLDIIVNHTADVIRYAENEYTYVDKETSPYTDTEGQPFEDANYASGKSFPSTDGTSFPYTPIFPNKSAAKAKTPAWLNDVTMYHNRGNSTFAGENSEYGDFYGLDDLWTERPEVVRGMTKIYADWVKNTGIDGYRLDTVKHTNLEFWPQFAEGIEKAAGDDFFMFGEVYSADQEIQSSYVREGGLPATLDFSFQEAARGFVTGASGATALSDLYAKDDLYTARDTGADRLPTFLGNHDMGRIGSFIASAATAETQLKRDQLAHELMFLTRGQPVVYSGDEQGFTGPGGDKDARQDLFASKSADYLDDDLIGTDRTHAVDNYNTRHPLYRTIADLGKLRKANPALTNGVQVTRYAAEGQGVFAASRIDTAKRSEYVVAVNNATTEQTVTFPVATAGTFKGLYGTNATLTSDGKITITVPALSSVVLKADKSLAAATAAPTVTITKPATGGSVPTRTELVAETTGDPLATVTFAAQVAGGPWTLVGTADKAPYRVYHDLTGLAGGAEVRYKAVVRDSRGRLASSTTKITVGTPEATSTAGYAVVHYQRPAGGYDDQNLYVWGDVDESMSTTWPDGQPFIGEDSYGRFAYVKLKPGAKSVGFIVVSDSGVKDVDADRTIDVTANPEIWIKQGDATVHPTRQAATGEPDPAQDQNKAIIHWRKADGNYDGWGLHVWEGAADPTDWASPLAPARIDSYGAVFEVPLAAGASSLSYILHSGDTKDLPSDQSLDFAKAGREVWLLAGQETRLLPLVKTAAGVGEIDVATSRAVWIDRRTVAWKTSTGDTLEPVGAGADGKVYDLVHAPAGGIGVANGELTGSYRSVRLSARRDGLTEAQREKFPHLWQHGAFTLPAGDITEILRGQVVVTERDAKGKLLSATGVQLSGVLDDVYAAATRAELGPAKGGVVSVWAPTARNVELEVYTGDTAAVRTMTRDARTGVWSARSLKNGDSYKFRVTAWQPATRQVVTASVTDPYSLALTADSTRSVFTSLDDAAGKPVGWDRLRKPPATAPAKIQISELSVRDFSIADDSVPPAERGTFSAFTRADSAGMKHLKELAGSGVTHLHLLPAFDFATIPEKRADQAQPPCDLASFPPDSEEQQACVAKVAATDGYNWGYDPLHYTVPEGGYAVDPANRTAEFRSMVTGVNRAGLRVVMDVVYNHTSAAGTDARSVLDQIVPGYYHRLLEDGTVANSTCCANTAPENAMMGKLVVDSIVTWAKAYKVDGFRFDLMGHHPKENILAVRKALDRLTLAKDGVDGKNIYVYGEGWNFGEVANNARFVQASQTELAGTGIGTFNDRLRDAVRGGGPFDENPRIQGFASGLLTDSNGDPVNGDAAAQKARLLHYQDLIKVGLSGNLRSYQFTSSSGATVSGEDVDYNGSPAGYNAAPGEAITYVDAHDNEILYDSLAYKLPQATTAVDRAKAQSVALATTVLGQGIGFVTTGSERLRSKSLDRNSYNSGDWFNAIEWDCAKGNGFGRGLPPKPDNESKYAYAKPLLADPALIPSCAAINLADSRYQELLKIRKSTPVFGLPTAAQVQKRLSFPLSGTAETPGVITMTLDGRGLDPKWKSVTVVFNATPSAVTQKVTSLAGKKVALHPIQQQSTDPAVRSASFAASTGTFTVPARTVSVFVQS
>NC_017093.1|WP_041831449.1|6597524_6597902_+|DUF1304-domain-containing-protein
MNTVAQVFAVVAALVHLGAGTLEAFFYRRPAVRKFLTGSTADAPEAQMWRFFIGLYNLFLAVGILVGLVMLHRGDESAGRALVIYVGCFMTVSGVIFLITHPKLWSGALGQFVPPGAAVAAALLT
>NC_017093.1|WP_157435482.1|6596446_6597130_+|FCD-domain-containing-protein
MRDRAYEELRRRILATELAPGARLVERDLAAELELSRIPLREALRLLEADGLVLLVPHKGALVAPFTPADVRDLFDVRESLEALAARLTAQRRDTAGLARLKDRLAAARAATAAGDSDGVAAANAGFHADLVDLSDNPLLSAMMRPLAARTHWLFRLTAQRDPDQQCAEHEELYAAIEAGAAEKAAELARDHVASGRETSIAQASRWSVPDVDPEAVAARRRRRVTK
>NC_017093.1|WP_014446246.1|6595729_6596278_-|DinB-family-protein
MGTDWNAQLRQQLDQHWRSRLRPRLAGLTDDEYFWEPVPDSWSVRPRGTSNASMAAGGGDMVFDWAYPAPDPPPVTTIAWRFGHIIVGVLGMRLARHFQGAPMDYLRHHYAGSAAEALSQLDTIYGQWASAVAGLGQDGLARPSGEEGYGDDSMGALVLHINREVIHHGAEIALLRDLYLRR
>NC_017093.1|WP_014446245.1|6593329_6595741_+|EAL-domain-containing-protein
MNVRQKLLGGYLLVALLLAATALVAWRADNASAEKAAVEEAKQLATGIASDIGNGLPVDTPDEVPIPLYYSQTGLNNYLQRLHTTQKRDVVVVDGGKYILADVIPANVGEIFDHDTGNEVGKTLTDGKARDFVETSADYPDGIKQVVVPMRSGQGAMLGAVILEYTPLYDQMMAGARQAQKVILTSSTIAVVLVLLIGFGVAGSVTRRIRALTSAVRVIRSGDYSHRVPSTGRDEIGTLARAFNAMAEQLERSAREILAKEYTDSILANAGEGICGVDATGRIAFANEAAGRITGVGVTGLLQREATTLMPEATGSLTPGTREGRLQRPDGTSVRVEYTISTIEKDDRTIGAVVVLRDVSRQRALEYDLRHQALHDGLTGLPNRKLLLDRLEHALTRSRASGEQVAILYLDLDGFKRVNDSLGHNAGDTLLRTAAERLIGLLRPQDTVARLGGDEFAVLLEPAGPDVVEAVARAALEALARPFLLHHREAVVTVSIGVVPDAARYTDADEVVRNADVAMYAAKDEGKNRFMIFETRMHEQLLSRLDQEARLREAVHRGELRLYLQPVAGVPDGRMYGAEALVRWQDPQRGLQQPGSFIPLAEETGMIIEIDRWILREACRMIRQWQDLNPRTAPAFVSVNLSAAHLEQPDLTQQVEVALAETGLSPHCLVLELTETVLMRDVAVTSARLEELRRIGVKIAIDDFGTGYSSLGYLRDIPVDVLKIDRSFINGLVGNGRQQELVSAVIQLGHTLGLRVVAEGVEESDQLALLTVMGCKFAQGYYLGRPEPAATLYERLNDRALTA
>NC_017093.1|WP_014446244.1|6592400_6593321_+|sulfite-exporter-TauE/SafE-family-protein
MDPIMALAGLGVGIIVGLTGMGGGALMTPVLVLLFGVHPVAAISSDLAASAIMKPFGGWVHARRGTVNWRLVGWLCAGSVPSAFAGALLLKQFGTDESVQHGVKIALGVALLLAVAGMLLKAWTGRRDAGRPPAAITVRPLPTLLVGVMGGLVVGLTSVGSGSLIIVALLALYPKLRANDLVGTDLVQAVPLVTAAALGHAIFGDLQLDIAGAVILGSIPGVLIGSRISSRAPGGLVRSALIIVLLASALKLFDVPTAVVGGVAGAAVLVAVGIGIAGRTGGRIACRIRPKRTPAPDDSILEDARR
>NC_017093.1|WP_172666635.1|6611435_6612869_-|argininosuccinate-lyase
MPETEEPTRLWGARFAGGPAEALARLSVSVQFDWRLAPYDLLASRAHARVLANAGLLDADELGKMLAALDDLESACAAGEFRPTVEDEDVHTALERGLLERLGSLGGKLRAGRSRNDQVATDLRLYLRDHARGVAVAVVELADALTEQAARNIDTPAPGMTHVQHAQPVSFGHWLLAHVQPLLRDLERLRDWDARTAISPLGSGALAGSSLPLDPAAVAKELGFSAPAPNSMDAVSDRDFVAEFLFTTALLGVHLSRLGEEVVLWTSTEFGWVELDDAFATGSSIMPQKKNADIAELARGKSGRLVGGLVAVLTMLKGLPLTYDRDMQEDKEPAFDAVDTLELLLPALAGMISTMTVRVDRLAAAAPVGFSLATEVADWLVRKGVPFRDAHEVTGKLVALCSARECELEDLTDDDLKTVSEHLDPSVREVLSVSSALAARTTPGSTGPGPVREQLATVQHKLDNWRQWAVEQVVPRH
>NC_017093.1|WP_014446257.1|6612961_6614020_+|succinyl-diaminopimelate-desuccinylase
MTSLDLTGDIVDLTRTICDIPSVSGDEKALADAVEAALRAYPHLEVLRDADAVVARTSAGRDTRVVLAGHLDTVPIAGNLPTTMQNQMVYGRGTVDMKAGVAVFLQLAALLDNPRHDVTYVFYDHEEVAASLNGLGRLVRNHPDWLAGDFAVLGEPSDGTVEGGCQGTMRVKITVPGVAAHAARSWRGSNAIHSAGAVLDVLRAYEPRRPVVDGLQYREGLNAVRIEGGIAGNVIPDLCTVFVNHRFAPDRDTDAAEAHLREVFAGFDLEVTDRAPGARPGLDQPAAKEFVDLVGREPQAKLGWTDVSRFAALGIPAINFGPGDPLLAHTDNEHVPADEIRKALQTLTSWLS
>NC_017093.1|WP_014446258.1|6614080_6615319_-|argininosuccinate-synthase
MTKRKIVLAFSGGLDTSYLLVDFREKGWDVVTANIDTGGLHSGEAEVVSARAEELGAIEHHVVDARAELYSRVVTYAIKANYLRNGAYPSCVGAERLIQAEKVVQVALEVGADAVAHGSTGAGADHVRYDAVIRALAPHLEIVTPVRDERLVREEEAEFLRSRGYAVSEKVKKYSINEGLIGTSIGGEETYGSWEYLPEDAWTYTKSIDAAPAEGVELLLTFEKGEVVDASYAGGDPLVEKDSPNYAILSALNVLGGEHGVGRGIHMGSTMVGNLARVGFEAPGMLILIAAHRELEKLVLSNRQQATKATLGNTYGDLLHEAVYFDPIMDDFRAFLDSSQTRVTGQVRVRLHKGNIVLLGSKSPYSLLDAATRSGVVYGHGSSLWTGEQARAFAHMYAVPGAIARAAATPAD
>NC_017093.1|WP_014446259.1|6615315_6616209_-|hypothetical-protein
MTFTPAVEARFPDFADHTDTLVGHGVEFFLASNETLRPQLNELPYGHKLTWLDFTDTAEKDWSIRDFLNYFNVINGIAFGDRGIPMPQWVMVDLILMPAAALIAGLPQDEFAAMVERSTFRFDTDVKQLLRTVQAEMRESGYRGPVPVGGYCAAPSAEPGRWVGWSLWSLMPAVGLGKAAKALALSAYRAQKLDGVTQYDNSALKVHTEFGALKILVATVPFHTSPGSFVYQSDLTLPPGGELPEPSFLLDPFDYGRQQAMQKDIEAGRSEFYVLPPGHVRRDGKTYVPILEKELPR
>NC_017093.1|WP_014446260.1|6616208_6616706_-|arginine-repressor
MSLPVTRAGRHARIVELIRSRTVRSQTELADLLAHEGVQVTQATLSRDLEELNAVKVSGAYLIPEDGKRPLRETSQGPARLIRLLRELLTGVDSSGNIAVLRTPPGAAQFLASALDRSGLADVVGTIAGDDTILVVARDAGPGSGAALAEKLGNWSRPDSLEGNS
>NC_017093.1|WP_014446261.1|6616702_6617635_-|ornithine-carbamoyltransferase
MTTRHFLRDDDLTPQEQDDVLNLAAEMKANRFGHTPLAGPRSVAVFFDKASLRTRLSFEAGIAELGGQPIIVDTQNTHFGRGETLADAGKVVSRYVAAMVFRTHGDERLAELASGVKVPVINALSDGYHPCQLLADLLTIRERFGGTSGRTLAYVGDAANNMAHSYLIAGAMAGMNVRVAGPSGFDPDPAVVARAAEIAAWTGGSVEVLRDPREAVDGAHVVATDTWTSMGQEEDGKDRLTPFWPYQVNKELLAAASPDAIVLHCLPAHRGEEITDEVFDGPQSVVFDQAENRLHAQKALLTWLLAVNER
>NC_017093.1|WP_014446262.1|6617631_6618786_-|acetylornithine-transaminase
MTTLSERWQQSMMNNYGGPTLGLVKGEGAVLTAEDGRQFVDFLGGIAVNALGHAHPAVVAAVTSQIQQLGHVSNLYIAEPPVALAELLLALAGRQGRVLFCNSGAEANEAAFKISRLTGRTHIVATHGAFHGRTMGALALTGQPAKQTPFLPLPGDVTHIEYGDTAALEAAVTDRTAMVIIEPIQGENGVVMPPPGYLAAARAICDRHGALLALDEVQTGIGRTGHWFHHQGEGVEPDIVTLAKGLGGGLPLGACLAFGPTADLLQPGMHGTTFGGNPVSCAAGLAVIRTIANEGLLDHVKRVGEQLRRGIEGLGHPLVSHVRGAGLLLGIVLTQPVAKDVAAKLLDAGFLVNPAQPDVIRLAPPLIISSDQADALIAALDGIR
>NC_017093.1|WP_014446263.1|6618782_6619694_-|acetylglutamate-kinase
MKAVEKAEILIEALPWLERFHGSTIVIKYGGNAMIDPALQAAFAADIVFLRLVGIKPVVVHGGGPQISRMLTKLGIESEFRGGLRVTTPEAMDVVRMVLVGQVGRELVGLINQHGPYAVGLSGEDAGLFTAVRRQAVIDGEPVDIGQVGDVDQVDTSAVDDLIAAGRIPVIATVAPDADGVLHNVNADTAASALAVALGARKLVVLTDVPGLYTNWPDTSSLTSEIDADALEKLLPSLESGMAPKMEACLRAVRGGVPAAHVVDGRVAHSTLLEVFTEEGFGTMVVPQSFQPPHPPPLNGLKA
>NC_017093.1|WP_014446264.1|6619690_6620863_-|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ
MTVTTPKGFRASGVAAGLKASGNPDVALVVNDGPDYTAAAVFTGNRVKAAPVLWSQQVLKGGVIRAVVLNSGGANACTGTQGFRDTHSTAEHTAAVLRSGPKPMMVGPGDVAVCSTGLIGELLPMDKLLPGVTAAAKALTADGGSRAAEAIMTTDTVAKNAVAQRAGWSVGGIAKGAGMLAPALATMLVVITTDASADNETLDAALRAATRVTFDRIDADGCMSTNDTVILLASGASNAQPTLAELTAAVTEVCHDLAQQLIGDAEGATKHIAIEVAGAASEADAVQVGRVVANNNLVKTALFGNDPNWGRILAAVGTTSAAFEPDRVDVAINGVWVCKGGAAAEDRSKVDLSGRDVQITINLREGEMSATIWTTDLSHAYVHENSAYSS
>NC_017093.1|WP_014446265.1|6620859_6621861_-|N-acetyl-gamma-glutamyl-phosphate-reductase
MGIRVAVAGASGYAGGELLRLLAGHPEFDLVTATAHSQAGSAVSAVHPQLAGLDLTLGATDAETLSGADLVFLALPHGQSAAVAAQLPTGTKVVDLGADFRLESAEQWTRYYGGGHAGTWTYGLPELPGARAAIAASDRVANTGCYAATITLALAPLIAAGVADPEDVVVVASSGTSGAGRNAKVNLLASEIMGDLSPYKVGAHQHVAEIKQATGAGSLSMTPILAPMPRGILATVTARRLNGGDPREALQAAYATEPFVHVLPEGQWPHTAATAGSNSCHLQATVDIDSGRIIVVSALDNLGKGAAGQAVQVANIMFGLPETTGLSVFGVAP

Crispr_ID: NC_017093_22

• CRISPR_ID: NC_017093_22
• CRISPR_location: 6923895-6923998
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_22

Consensus_repeat	Method
GCTGGTTGCACCCGGCCGCGCAGCC	CRISPRCasFinder

spacers of NC_017093_22

>22.1|6923920|54|NC_017093|CRISPRCasFinder
CGTCGGGTCATGACCTCGACCCGTGGGCCCGTGCGGCGCCAGCCGCCCGGTCAG

CRISPR arrays and Neighbor proteins around NC_017093_22

CRISPR arrays

The CRISPR arrays of NC_017093_22

>merge|NC_017093|22|6923895-6923998|CRISPRCasFinder
GCTGGTTGCACCCGGCCGCGCAGCCCGTCGGGTCATGACCTCGACCCGTGGGCCCGTGCGGCGCCAGCCGCCCGGTCAGGCTGGTTGCACCCGGCCGCGCAGCC

>NC_017093|22|21|6923895-6923998|CRISPRCasFinder
GCTGGTTGCACCCGGCCGCGCAGCC	CGTCGGGTCATGACCTCGACCCGTGGGCCCGTGCGGCGCCAGCCGCCCGGTCAG
GCTGGTTGCACCCGGCCGCGCAGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_014446547.1|6919905_6920949_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|223521
NC_017093.1|WP_014446540.1|6913611_6913767_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014446553.1|6926252_6926462_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014446544.1|6916023_6916908_+|NAD-dependent-protein-deacetylase	unknown	unknown	gnl|CDD|238700
NC_017093.1|WP_014446555.1|6929036_6931556_-|DNA-topoisomerase-IV-subunit-A	unknown	unknown	gnl|CDD|235503
NC_017093.1|WP_014446552.1|6925379_6926207_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_017093.1|WP_014446545.1|6917006_6918011_+|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NC_017093.1|WP_014446548.1|6920945_6921926_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NC_017093.1|WP_014446541.1|6913783_6914836_-|DUF2183-domain-containing-protein	unknown	unknown	gnl|CDD|227187
NC_017093.1|WP_041830184.1|6915695_6915926_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014446549.1|6921929_6922925_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NC_017093.1|WP_014446554.1|6926520_6927477_+|aldo/keto-reductase	unknown	unknown	gnl|CDD|381330
NC_017093.1|WP_014446546.1|6918149_6919838_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173874
NC_017093.1|WP_014443070.1|6927723_6928971_-|IS701-family-transposase	unknown	unknown	gnl|CDD|379252
NC_017093.1|WP_014446559.1|6937607_6938378_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014446557.1|6933756_6934365_-|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl|CDD|143636
NC_017093.1|WP_014446542.1|6914924_6915626_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014446560.1|6938451_6938961_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014446556.1|6931566_6933648_-|type-IIA-DNA-topoisomerase-subunit-B	unknown	unknown	gnl|CDD|235501
NC_017093.1|WP_014446558.1|6934542_6937356_+|LuxR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|226415

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_014446547.1|6919905_6920949_+|ABC-transporter-ATP-binding-protein	gnl|CDD|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	5.34879e-116
NC_017093.1|WP_014446544.1|6916023_6916908_+|NAD-dependent-protein-deacetylase	gnl|CDD|238700	cd01409, SIRT4, SIRT4: Eukaryotic and prokaryotic group (class2) which includes human sirtuin SIRT4 and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins have been shown to regulate gene silencing, DNA repair, metabolic enzymes, and life span.	5.32854e-123
NC_017093.1|WP_014446555.1|6929036_6931556_-|DNA-topoisomerase-IV-subunit-A	gnl|CDD|235503	PRK05561, PRK05561, DNA topoisomerase 4 subunit A.	0
NC_017093.1|WP_014446552.1|6925379_6926207_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.54374e-13
NC_017093.1|WP_014446545.1|6917006_6918011_+|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.14242e-102
NC_017093.1|WP_014446541.1|6913783_6914836_-|DUF2183-domain-containing-protein	gnl|CDD|227187	COG4850, COG4850, Uncharacterized conserved protein [Function unknown].	2.83196e-56
NC_017093.1|WP_014446548.1|6920945_6921926_+|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	8.42921e-95
NC_017093.1|WP_014446549.1|6921929_6922925_+|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.55441e-73
NC_017093.1|WP_014446554.1|6926520_6927477_+|aldo/keto-reductase	gnl|CDD|381330	cd19104, AKR_unchar, uncharacterized aldo-keto reductase (AKR) superfamily protein. This family includes a group of uncharacterized AKR superfamily proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance in both health and industrial applications.	2.58864e-104
NC_017093.1|WP_014446546.1|6918149_6919838_+|ABC-transporter-substrate-binding-protein	gnl|CDD|173874	cd08509, PBP2_TmCBP_oligosaccharides_like, The substrate binding domain of a cellulose-binding protein from Thermotoga maritima contains the type 2 periplasmic binding fold. This family represents the substrate-binding domain of a cellulose-binding protein from the hyperthermophilic bacterium Thermotoga maritima (TmCBP) and its closest related proteins. TmCBP binds a variety of lengths of beta-1,4-linked glucose oligomers, ranging from two sugar rings (cellobiose) to five (cellopentose). TmCBP is structurally homologous to domains I and III of the ATP-binding cassette (ABC)-type oligopeptide-binding proteins and thus belongs to the type 2 periplasmic binding fold protein (PBP2) superfamily. The type 2 periplasmic binding proteins are soluble ligand-binding components of ABC or tripartite ATP-independent transporters and chemotaxis systems. Members of the PBP2 superfamily function in uptake of a variety of metabolites in bacteria such as amino acids, carbohydrate, ions, and polyamines. Ligands are then transported across the cytoplasmic membrane energized by ATP hydrolysis or electrochemical ion gradient. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	7.22628e-124
NC_017093.1|WP_014443070.1|6927723_6928971_-|IS701-family-transposase	gnl|CDD|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.60534e-79
NC_017093.1|WP_014446557.1|6933756_6934365_-|adenylate/guanylate-cyclase-domain-containing-protein	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	7.48636e-41
NC_017093.1|WP_014446556.1|6931566_6933648_-|type-IIA-DNA-topoisomerase-subunit-B	gnl|CDD|235501	PRK05559, PRK05559, DNA topoisomerase IV subunit B; Reviewed.	0
NC_017093.1|WP_014446558.1|6934542_6937356_+|LuxR-family-transcriptional-regulator	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	7.68342e-36

Protein sequences

>NC_017093.1|WP_014446549.1|6921929_6922925_+|ABC-transporter-permease
MSIPTSSIEQVIPVQGSMAQPAKVRRRRFRFVANKKAATGLIILGVYLLFAVIGPWVAPYDPGARSNALVQPPSADHWMGTTHLGQDVLSQLLTGTRSVIFVGFFAGIVATVLSVLIGVTAGYVGGKTDEVLSALSNVFLVIPALPLIIIITSTLESAEDWLIALVIGLTSWSWNARVLRAQTLSLRRRDFVEAARAAGERTWRVIGFELLPNLTAVIASGFVGTVIFAVLSEITLAFIGVTSATTWNWGTILFWAQGQQALAQNAWWWFVPAGLAIAILGTALSLINFGIDEFVSPRLRSMGSTKLRTATGKTVRMRIGFTPVIQKETAP
>NC_017093.1|WP_014446548.1|6920945_6921926_+|ABC-transporter-permease
MKYFLQRLAFYLFTAWAAITLNFFIPRLIPGDPVQALVTKYQGQLSSKAIESLYVLFGLDKDASLWSEYVTYWKQLLTGDLGLSFTFFPTPVSEIISNSLPWTLLLVGITTVISFFLGTGLGILAGWRRGSWADGLLPVTTFLSSVPYFWLGIIAIYLLTGPDSFFPSSGGFDAGLVPAWDLYFIPSAIQHSLLPALTILISSVSGWILSMRNMMVTVASEDYITVAHAKGLSDRRVAMSYAARNALLPNVSGFALSLGFIVGGTLLVEIVFSYPGVGFQLFQALGASDYPLMQGIFLIITISVLVANLLADIAYLLLDPRTRKEG
>NC_017093.1|WP_014446547.1|6919905_6920949_+|ABC-transporter-ATP-binding-protein
MTSIPDTKAPAGEVVLEAIGLTKHFPVRRRLRDLFSGRHDAVHAVDDVNLTLRRGRVVALVGESGSGKSTVARLLAQLYPRTGGDIRLHGTSTRVTSGSAFRRYCAQVQMIFQDPFASLNPVHTIRYHLSRSLQIHGNAGDDLETALHQLLERVSLTPPERYLDKFPHELSGGQRQRVAIARALGAEPKALLADEPVSMLDVSIRLGVLNLLRDLKERLNLAILYITHDIASARYFADETMVMYAGRMVEGGDSETVTQAPAHPYTRLLIESAPDPDRLTGLSEAAGEERGNGEPPSLIHPPTGCRFHPRCPVAMPRCSVELPVPLEIGDVPGHWAACWLYDGEGAR
>NC_017093.1|WP_014446546.1|6918149_6919838_+|ABC-transporter-substrate-binding-protein
MQRRKLFAVALAGALATGGLSACGDSPNANNKNAAKGEQVDYLSIGMPNGTVTESNNPFVQTSAAAGLGYRWMIFEPLGQWNNTKPSEPLTPWLASSITWSPDYKTVDLVIRDGATWSDGKPLTAEDVVFTHTMIKGNDALNLFAIPYDQITADGNKVKMTFKTSQFTTHHKVIGQTPIVPKHIWEKLSDPATDPIKEPVGSGPYALKSFSQQATILTARESGYWGTQPKVKELRYTSFADNNAQATALATGTSEWSFVFIPNYEQTFVAKDPEHYKVWAPGVLGIHGLYINTTKKPFDDPALRRAMNMVINRNDIFVQAEAGYFHPEIKSVTGLPEGAGDAYIADEYKGKTFSVDVEGAKALLTQSGYKLEGNVLKDKTGKPVTIKLSDPAPWSDYQTSLEIIKSNLAEIGIAATVEKPNQNVWDANVQKGDFEASMRWTNGGSTPFDIYQTVMDGDLMKPIGTAAQQGNFGRFDSPEATAALKAYSNATDEGARKTALATIQKIFVEQAPMLPVGSDNVGAAYSTKNWIGWPTDADSYAPAQPTQAAALQVVLKLQPANS
>NC_017093.1|WP_014446545.1|6917006_6918011_+|LacI-family-DNA-binding-transcriptional-regulator
MPITIADVAARAKVSKTTVSRVLNGKGELDETTAARVRAVIEELGYVPSARAVNLARGRTRVVGMLVPSLTWPWMGEVLQGAVDVLEAENYGLLLFTCNRGDDSMRQFAAQVAAKSFDGLLVIEPEGTLDYIANLHARGLPMVLIDDRDQISGGSIPTVGTTNHTGAADAAHHLLGIGRHKPLVITGPSRFGCTQQRTDGFLSVYADAGIPLSADRVMLGDFKVGCGVDNIRQAIETGIEFDAVFCHNDLSAFGAMQAIQESGRSVPGDVAVVGFDDIPMAAHAKPALTTVHQPLREMGEAAARTLLAHFEGAPLPNRPTIIPATFTVRDSTAA
>NC_017093.1|WP_014446544.1|6916023_6916908_+|NAD-dependent-protein-deacetylase
MGVMDLSVVEQVARLDAWIAEGGVAVLTGAGLSTDSGIPDYRGPSGSARRGTPMTYQTFTSDPIARRRYWARSHLGWRTIGGARPNEGHAAVARWQESGLLAGLITQNVDGLHQAAGARDVVELHGNLSRIVCLDCRELTSRVELEHRLTAANPDFAAVATTINPDGDVELDDDELSGFTVVPCRSCGGVLKPDVVYFGETVPADRVTRSFELVETARTLLVLGSSLTVMSGRRFVLRAVREGIRVAIVNRGVTRGEPYADMVIDAPLGVVLPNLATDTDNHRFVNTVTVSKPK
>NC_017093.1|WP_041830184.1|6915695_6915926_-|hypothetical-protein
MIEKVRDAHRPRAGRRLLRFLAHLAVLALAATLHLPVTSAVPAPPTPLADFAVTAFPALKAGEVPQATGPRAPPAA
>NC_017093.1|WP_014446542.1|6914924_6915626_-|hypothetical-protein
MDSALQSFLSAVPQAAAIWLTILLLLAVAVVCARLPRATALPAPEPDENPYAAEVESAVAEASAAAGRRRAEWLESQQAVDAAWTAYEQAEADARRIAAATAYPLMSRRRKPGENVDRQRYLHRAATELCRTQDLSIGQLNDVYAHRGWNPRLHPVQQEAALHAAVREHRLEAYRKAVAAEQAAWRSAEAAAETLRDLRAEAAAARLRGPASQAADQQWWSEQWTGAELPAAA
>NC_017093.1|WP_014446541.1|6913783_6914836_-|DUF2183-domain-containing-protein
MVTVTPAGDSTSVNRAAMHRAALVEDAIHDIIERRLVGRGWKPYITAYTGYGAPGWARVMGRVLLARPGTVSKRREKVRGWRSFTTTPVNGAVVRIELGGTVTETRSDRSGYVDCKVKGDLEPGWGTARLHTEGAAPVDAPIRVIDPAVKFGVISDIDDTVMVTALPRPLLAAWNTFVLDEHARTAVPGMAVLYERMVNAHPGAPVIYLSTGAWNVAPALTRFLSRHLYPAGPILLTDWGPTPDRWFRSGQEHKRKSLRRLADEFPHIRWLLIGDDGQHDQEIYSEFARSHPENVSAVAIRRLSPTQAVLAGAIPGPSETAEVVPSGGKTWFSAPDGAGLWSVLRDTDVV
>NC_017093.1|WP_014446540.1|6913611_6913767_+|hypothetical-protein
MRWWKVVGLAGLAGVAATGAVIARAERRRRAYTPDEIRQKLHDRVSEATSD
>NC_017093.1|WP_014446552.1|6925379_6926207_+|class-I-SAM-dependent-methyltransferase
MTDYLDVNRANWDERAAPHAASPDYHVEDFATDPAYLSQVVRFDMPRLGDIAGLRGVHLQCHIGTDTISLSRLGATMTGLDFSGASVEQARAIAARAGADVTFVQSDVYAAREALDGEFDLVYTGIGALGWLPDITRWARTVASLLAPGGRLFIREGHPILWALDYDRTDGVIALSEPYFEHEEPQIYDEPGTYVTSDHQFQHTTTHEWNHGLGEIVTAVLDAGLTLTGLEEHQSVPWDALPGRMREIGGGEHQLIEKPSRLPHTYTLQARRLTN
>NC_017093.1|WP_014446553.1|6926252_6926462_+|hypothetical-protein
MRIGAVIVVIWLVLGVVAAFERGYFKNTGDASCAEAGTVIVTTIAGPLNWMGVNPKITCDVPDVPEPSE
>NC_017093.1|WP_014446554.1|6926520_6927477_+|aldo/keto-reductase
MELRDFGRLGRISALTLGGGGLGGVWGATDRSEAVATVHAAIDAGITMFDVAPSYGDDFEAERVIGEALRNSPDVQVTSKVQVHDVPPGGDFARLISSSLEGSLTRLGRDHLDLFLLHTQLLPRDGSATAPGTIHWQSYQDAVVPAFEHLRETGRIRAWGITAVGHPASVLDALRAPARPNAAQVIVNPLDLNGDMWIYPTVPSENQAVLATAQSQGVPVLGIRVAAAGSLTDSLDRSVPPDHPAAIDFARAAPFRELAADWGTSAATLAHRYALSVPGVASVILGVKNRAELTECLKAEAEGPLPPEQLAALRVLRP
>NC_017093.1|WP_014443070.1|6927723_6928971_-|IS701-family-transposase
MDVAEADRLRDDLAEFASDVFASLTRAGWQDRAAAYLQGLMIDGRRKSIQPMAARLQGVHEQALNHFVTNSPWQVEPVRRRIAALADQAIVPTAWAIDDTGLLKCGTASPCVARQYTGTAGKVTNCQIAVSVSMVTDTASCPVDWRLFLPESWDPASPKATSDVHNRRRRAGISDDVTHREKWRLALDMIDELLRWGHRPPLIVADCGYGDAAEFRLALTERGLPHLVQVSGRLTAYPASTIRTAGDYAGVGSYPTPRYQQPAPTLTELITTGTGKARRVTWRPGSRSRGGRPLLMSSHFVFTRVRPAGRTLLSAHRGEDLPEAWLIAEWPPGNPEPIKYWLSDLPARTARRTLIRWAKLRWRIEHDYREVKTGLGLDHYEGRTWQGWHHHVTLVSAAHIFLTLQRLDPKTHAPE
>NC_017093.1|WP_014446555.1|6929036_6931556_-|DNA-topoisomerase-IV-subunit-A
MARRKSENRVDLSAFDQPGARVIDNPLTTEVEDSYLEYAYSVIHSRALPDARDGLKPVHRRILWSMSEQNHRPDRPYVKSARVVGDVMGKYHPHGDVAIYDALVRLAQDFSLNTPLIDGHGNFGSPDDGPAAARYTEARMSPEAMLLVGELGEGTVDFKPTYDGSEQEPKVLPAAFPNLLVNGTSGIAVGMATNMIPHNLGEVVAAARHLITHPEADLDELMRFVPGPDLPTGGQLLGLDEVRRAYETGRGVVRIRARAQTGLLEGGRGRQAITVTELPYGVGAEKIIEAITDEVKGKLITSGPRRGQRQAARLVGISDVKDLTDREHGTRLVIECKIGVNPTALLADLYRLTPLESSFGINNLVLVDGQPRTLGLKALLEVFVQHRYDVVTRRTTFRRTKREDRLHLVDGLLIALIDIDRVVALIRASDDAAAAKAGLMSEFGLSEIQATYILDTPLRRLTRFDRIELETEQERLRNEIAELTRILDNEDVLKQVVSDELAEVATEFGRPRHTTLIDGDLKEVLAASVPAGPLEVADDPCQVILSATGLIARTAAESEESTEARKRSGRIKHDAVRAVIHSTARGRILLVTNRGRAFKTDVLTLPVLPDQSGTVSLRGGMSASELVPLHKGERVVGMAPLAAGDSPGLALGTKQGIVKVCAPEWPVRSDEFEVITLKEGDEVLQATWLTDGAESLVFVTSDASLLRFPAKLVRPQGLKGGGMAGINVAAEAEVLSFNAVSTSDPQHGEPMVVTSTGTQVKVTPFGLYPAKGRATGGVRVQRFLKGETALSVAWVGPRPVGASSTGDPVELPEVDSRRDGSGTAVIMGPQLVGHLIERD
>NC_017093.1|WP_014446556.1|6931566_6933648_-|type-IIA-DNA-topoisomerase-subunit-B
MADREYCLVTAQPETLYGADDLTHLEGLDAVRKRPGMYIGSTDSRGINHLANEIIDNCTDEGVAGFATKVAVTLHSDGSVQVDDDGRGIPTDVHGKSGLSGVELVLTRLHAGGKFGGSGYKTSGGLHGVGASAVNALALRFDVTVKRDGKVHEISFQRGVPGSFDGPGPEASFTREAGLRVVRKMKRGEPSGTSIRYWYDARYFETGARLDVDAVRTKLRNTAFLVPGVQYTLFDATAEEPATETFHYPNGLTDMVEFLTPSGDKPVSGILMVTGEGTYKENAADANGVMQSNVVRHAQIEVAFRWGTGYERTVECFTNTIRNVHGGTHRKGFERALVRSLTEAVRNTRGLLKPKEEPPVLDDLLEGMTAVIHVRVPEPQFTSQTKDELSTAGVTRVMQGLVEAYVKEWIENRKTKAEARTVLQKVVDAARVRLTQKQQKDAARRKTALEGASMPAKLVDCRAIGIDRSELFIVEGDSALGTARMARSSEYQALLPIRGKILNVQKASLQQVLDNAECSAIVQVLGAGSGRTFEIGAMRYGRVMIMADADVDGSHIRTLLITLFAKYMRPVIEHGRLFAAMPPLHKVVTKGRNAETIYTYTQQEMESTVSRFERGGRQVQKPVPRFKGLGEMDADELWETTMNPAARTVRRITIEDAERAEATLELLMGERVEPRKNWLIEAAGRIDQETIDA
>NC_017093.1|WP_014446557.1|6933756_6934365_-|adenylate/guanylate-cyclase-domain-containing-protein
MTTITMAEQERRQDVTVLFIDIVGYTTLVDRLDCADVRALQRDYFSAVSAVVRACGGIVEKYVGDAVMAVFGAGEAGFGPEAAAAAVRAGLSVQETLRGRLLAGRFPVRTRVGLATGEVILDPLAAFDGGYAMVSGSVVTTASRLQSYAPHDTVVVCAATRAVTDTLIAYQELPPVSVPGKPYPLDLFRALQPQTASLAAVA
>NC_017093.1|WP_014446558.1|6934542_6937356_+|LuxR-family-transcriptional-regulator
MEGQEDDGPLVGRTGTLAEIQSNLRNVGTGGTAAVFVTGESSVGKSRLLRETADALRGTGFAVLSGTCLDIGDASPLHPVLQALRRHDGAPITATAPGDAGALLDRVSHDLRAIAGDQQLLLVLDDLQWADRSTRQLLLYLLAGLGDVRISVLAAIRAEALHGTHPLRRVLAELRRLRSVRVVDLSPLDQDQTRELVTAIAGDDVATEDADRVYKRSGGNPFIAEELARDLRDGRVELSDTLREIFLTRVDELPAHAHQVVHAMAAGVEPVDHAVLARVVPLPEDQLLEAIRAAVAHRFVSSDGDGYRLRHRLVAEVLEHEVLPAEATALHRRYAEALEPETGEPDHARLAHHWQRAGVPERALPPVVAAARSAEALYGFAEAHRYWSIALQLVAEDDAERTALLGNAAESAHQCGEHLLALSRLEELAGRKDAPGLGELHLRRARYLAAAGRFAHAESEYELALGAPDCTPQLRASAAAFLAELLVQLARYADAHERAREALELAAVNGTTADLVRASAALGFSAAFREDPDAGLAVIRHAVEIAERSGHPDDLGVAYLHLAELLTGPLNSIEEGVLVARRGAERLSTLGGGRTHQSRLLAIAANGLFRIGQWTEADAVLEAAMRHRPSGAEAVELLLARCRLLVGFGDLDDASRDLDAAAILLAGGGARHVLPMLTLRAGLAMWLGEHADARTAVQRGITETRSDDLVLLGVLVWHGLRAEAEAHAAGKPVDHSAVRRLLMVRDRMASNADSAGPAARAIIDAYLDLCAAELSRIEGRHDPAPWARAAAIWDRRQQPYPAAYARLRHAEASLQRKVRRAAAISGLREAYATATAMGARPFAAEIVGIAHRFRVTLADDMPTVPMALPDQPVDELATLTGREREVLAAVAEGLTNREIGERLFISERTVGVHLGHIFDKLQVRTRVQASRVYLTAA
>NC_017093.1|WP_014446559.1|6937607_6938378_+|hypothetical-protein
MTQAIWGPVQQQMSGLLKEHPDDVPGVVDQLTKLQDVLCQVPPLLHSNPLADFNQLYLTITENVLERLYAGKFKDPAFLSRLDVEFAARYFDALRYWTDGSPACPGVWAGLFGRIPGPDARPLPSAVAGVNAHINFDLPFALVTTFDHLGTDPIDGSDQHHDYLQVNDIFNDEIPGLRRGYLDRWQLLIDTMNGDLDDWWQGEMVEYTRNVAWRNAQKIWSIRHDMIALDKHRRRLDDTATGLGKLLLSPFAGFLQ
>NC_017093.1|WP_014446560.1|6938451_6938961_-|hypothetical-protein
MTRTGKLVILCSVLALAGCGQAGAAPEAPPESPVASAAAGGEDFELVALEAAGFAEEGEARDGGEEKVRPRAVRRLLRQNTLHGEVVVQGRDGVRTIVVQRGDVTAADDAGFTVKSADGFTLTWAYGDPLRVVQNHEKAERDVVRPGVRVAVGGARDGAKVAARLIVVR

Crispr_ID: NC_017093_23

• CRISPR_ID: NC_017093_23
• CRISPR_location: 7045549-7045640
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_23

Consensus_repeat	Method
CCGCCGGACGACCGGCCCACCGACCC	CRISPRCasFinder

spacers of NC_017093_23

>23.1|7045575|40|NC_017093|CRISPRCasFinder
GCGGGGCACGGTCTACCCCATCGAGGGCGACGAGATGCCG

CRISPR arrays and Neighbor proteins around NC_017093_23

CRISPR arrays

The CRISPR arrays of NC_017093_23

>merge|NC_017093|23|7045549-7045640|CRISPRCasFinder
CCGCCGGACGACCGGCCCACCGACCCGCGGGGCACGGTCTACCCCATCGAGGGCGACGAGATGCCGCCGCCGGACAACCGGCCCACCGACCC

>NC_017093|23|22|7045549-7045640|CRISPRCasFinder
CCGCCGGACGACCGGCCCACCGACCC	GCGGGGCACGGTCTACCCCATCGAGGGCGACGAGATGCCG
CCGCCGGACAACCGGCCCACCGACCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_014446636.1|7042026_7042893_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|225117
NC_017093.1|WP_014446638.1|7043569_7043752_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014446650.1|7055662_7056439_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|225130
NC_017093.1|WP_014446649.1|7055177_7055666_+|DUF1990-domain-containing-protein	unknown	unknown	gnl|CDD|378157
NC_017093.1|WP_014446642.1|7047964_7048762_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|184875
NC_017093.1|WP_172666704.1|7054162_7055086_-|diacylglycerol-kinase	unknown	unknown	gnl|CDD|224513
NC_017093.1|WP_041830191.1|7030503_7036830_-|DUF11-domain-containing-protein	unknown	unknown	gnl|CDD|334634
NC_017093.1|WP_014446635.1|7041388_7041820_+|SsgA-family-sporulation/cell-division-regulator	unknown	unknown	gnl|CDD|377399
NC_017093.1|WP_051042610.1|7028366_7028726_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014446645.1|7050897_7051671_-|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl|CDD|377028
NC_017093.1|WP_172666703.1|7053161_7054130_-|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl|CDD|377085
NC_017093.1|WP_014446639.1|7043737_7044652_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_172666702.1|7046463_7047954_+|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|143635
NC_017093.1|WP_014446633.1|7037038_7040197_-|AfsR/SARP-family-transcriptional-regulator	unknown	unknown	gnl|CDD|274846
NC_017093.1|WP_014446644.1|7050391_7050901_-|DUF664-domain-containing-protein	unknown	unknown	gnl|CDD|368218
NC_017093.1|WP_041830193.1|7040704_7041112_-|TIGR02611-family-protein	unknown	unknown	gnl|CDD|131660
NC_017093.1|WP_014446637.1|7042973_7043429_+|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl|CDD|273242
NC_017093.1|WP_157435146.1|7049091_7050336_+|hypothetical-protein	unknown	unknown	gnl|CDD|227511
NC_017093.1|WP_014446646.1|7051670_7053143_-|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239486
NC_017093.1|WP_014446630.1|7028965_7029553_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_014446636.1|7042026_7042893_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	2.32614e-22
NC_017093.1|WP_014446650.1|7055662_7056439_+|MBL-fold-metallo-hydrolase	gnl|CDD|225130	COG2220, COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only].	4.07566e-36
NC_017093.1|WP_014446649.1|7055177_7055666_+|DUF1990-domain-containing-protein	gnl|CDD|378157	pfam09348, DUF1990, Domain of unknown function (DUF1990). This family of proteins are functionally uncharacterized.	6.41681e-58
NC_017093.1|WP_014446642.1|7047964_7048762_+|alpha/beta-fold-hydrolase	gnl|CDD|184875	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional.	6.57133e-16
NC_017093.1|WP_172666704.1|7054162_7055086_-|diacylglycerol-kinase	gnl|CDD|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	2.9007e-43
NC_017093.1|WP_014446635.1|7041388_7041820_+|SsgA-family-sporulation/cell-division-regulator	gnl|CDD|377399	pfam04686, SsgA, Streptomyces sporulation and cell division protein, SsgA. The precise function of SsgA is unknown. It has been found to be essential for spore formation, and to stimulate cell division.	7.1959e-40
NC_017093.1|WP_172666702.1|7046463_7047954_+|GGDEF-domain-containing-protein	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.19243e-53
NC_017093.1|WP_172666703.1|7053161_7054130_-|YihY/virulence-factor-BrkB-family-protein	gnl|CDD|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	2.80938e-31
NC_017093.1|WP_041830191.1|7030503_7036830_-|DUF11-domain-containing-protein	gnl|CDD|334634	pfam01674, Lipase_2, Lipase (class 2). This family consists of hypothetical C. elegans proteins and lipases. Lipases or triacylglycerol acylhydrolases hydrolyze ester bonds in triacylglycerol giving diacylglycerol, monoacylglycerol, glycerol and free fatty acids. Lipase EstA is a extracellular lipase from B. subtilis 168.	1.12326e-10
NC_017093.1|WP_014446645.1|7050897_7051671_-|endonuclease/exonuclease/phosphatase-family-protein	gnl|CDD|377028	pfam03372, Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. This family includes: AP endonuclease proteins EC:4.2.99.18, DNase I proteins EC:3.1.21.1, Synaptojanin an inositol-1,4,5-trisphosphate phosphatase EC:3.1.3.56, Sphingomyelinase EC:3.1.4.12, and Nocturnin.	3.2216e-17
NC_017093.1|WP_014446633.1|7037038_7040197_-|AfsR/SARP-family-transcriptional-regulator	gnl|CDD|274846	TIGR03903, TOMM_kin_cyc, TOMM system kinase/cyclase fusion protein. This model represents proteins of 1350 in length, in multiple species of Burkholderia, in Acidovorax avenae subsp. citrulli AAC00-1 and Delftia acidovorans SPH-1, and in multiple copies in Sorangium cellulosum, in genomic neighborhoods that include a cyclodehydratase/docking scaffold fusion protein (TIGR03882) and a member of the thiazole/oxazole modified metabolite (TOMM) precursor family TIGR03795. It has a kinase domain in the N-terminal 300 amino acids, followed by a cyclase homology domain, followed by regions without named domain definitions. It is a probable bacteriocin-like metabolite biosynthesis protein. [Cellular processes, Toxin production and resistance].	1.00184e-44
NC_017093.1|WP_014446644.1|7050391_7050901_-|DUF664-domain-containing-protein	gnl|CDD|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	7.63263e-31
NC_017093.1|WP_041830193.1|7040704_7041112_-|TIGR02611-family-protein	gnl|CDD|131660	TIGR02611, Putative_membrane_protein, TIGR02611 family protein. Members of this family are Actinobacterial putative proteins of about 150 amino acids in length with three apparent transmembrane helix and an unusual motif with consensus sequence PGPGW. [Hypothetical proteins, Conserved].	6.11098e-19
NC_017093.1|WP_014446637.1|7042973_7043429_+|Rrf2-family-transcriptional-regulator	gnl|CDD|273242	TIGR00738, Putative_HTH-type_transcriptional_regulator, Rrf2 family protein. This model represents a superfamily of probable transcriptional regulators. One member, RRF2 of Desulfovibrio vulgaris is an apparent regulatory protein experimentally (MEDLINE:97293189). The N-terminal region appears related to the DNA-binding biotin repressor region of the BirA bifunctional according to results after three rounds of PSI-BLAST with a fairly high stringency. [Unknown function, General].	1.23669e-34
NC_017093.1|WP_157435146.1|7049091_7050336_+|hypothetical-protein	gnl|CDD|227511	COG5184, ATS1, Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton].	7.02958e-35
NC_017093.1|WP_014446646.1|7051670_7053143_-|phosphatase-PAP2-family-protein	gnl|CDD|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	4.40397e-37

Protein sequences

>NC_017093.1|WP_014446639.1|7043737_7044652_-|hypothetical-protein
MSPIGTVKRELLVRHLQAWAAGALHRARRATYVHGYADADGGAAAETAVRVLADLPDLARGRELSMVALGDDVTGVGERLVAAQREAGTASGLAVLPVGGGTDARLAVALKAAGASHVPLLAFLDAASAGEPPAAATVAAVAAGKPAEVLLALAPGVAVEPYRRIGFPLVTAAELATGEEPGEVLVFATTSGKSLESFKEALWAVDEFAGVRLRDPGDPERHLIDISLTPHPGPLRRELLAHLSGVGAATVTDLRTFTMTETVYRAADATRVLHTLVDAGTVTRRPEHGRLGGDVEISLPSPAA
>NC_017093.1|WP_014446638.1|7043569_7043752_+|hypothetical-protein
MGLVFRSRKKFGPLILNFTENGYSSWSLKIGRWSWNSRTRAHRVDLPGPMSWKQDKSRSR
>NC_017093.1|WP_014446637.1|7042973_7043429_+|Rrf2-family-transcriptional-regulator
MQISARGDYAVRAALSLAQAYPALMSAQAIAQEQEMPRKFLEAVLADLRRAGVVRAQRGAEGGYTLSHPPRDVAVGQIIRAVDGPLAGVRGLRPEETQYTGAAENLPSLWVAVRAAVREVLDEVSLAELLSGKMPAHVRKLTTRPDAWQPR
>NC_017093.1|WP_014446636.1|7042026_7042893_+|helix-turn-helix-transcriptional-regulator
MPAMTSADTAHAYTLPDWAGISGCALPVTAGAVTGLLAHHALLLTVTGPLVAEVDFTVHRCEPGTLLWIRPGQALRVEPGKHESTTIVFRPGLFGPDDLPGLAPDDPGGPARHPIPLTGSAEFDSLVRDAAGPPGTTAAALLRHELAALLLRLSLLDPAPESPGHVESRTFERFRRRLEAGYPQTRRVEDYAAELGCSVRTLTRASLAITGRTAKQVVDDRVALQARRLLAATSLSVAEVGRNLGFGEPTNFGRFFHRETGLSPGQFRGRYVDEPSGGGIPAQRRPSD
>NC_017093.1|WP_014446635.1|7041388_7041820_+|SsgA-family-sporulation/cell-division-regulator
MSTIRPTTVEVETSLRLVAPDATALPVRASLRYDPADPYAVHVLFHAESAGGEAVSWSFARELLVTGLDEPAGIGDVRVWPWATPRGDFVALALSSPDGNALFEVPRSVLVRFLRRTYVVVPRGRESDHLDVDAAVNRLLAGR
>NC_017093.1|WP_041830193.1|7040704_7041112_-|TIGR02611-family-protein
MGPKTDDGASDVRVLDRIRSNSTGRLALKIGVGVVGGLVVAVGIVLIPFPGPGWAIVILGLAILAIEFHWARGVLEFTKRHVQNWTHWIGRQSLPIRALVGLVGLIFIWAVVWASVRISFGVDLVQVALDWLKAR
>NC_017093.1|WP_014446633.1|7037038_7040197_-|AfsR/SARP-family-transcriptional-regulator
MVRDDHGRRAGWDNVRFEVLGPFQVRDGERVVDIGRPQHRAVLAALLIDAGRVVPAEVLLGRVWGEQPGAGGTASLYACISRLRKRLGPIIVTQAPGYRLDVAGRDIDAVRFSELVSAARRAIAAGRPEDARAHVTEALALHRGTPYGGIRSDFAAHEVSRLEDQVLAATELAAELDLTLGREADLVTWLPDTVAAHPLREGMRGTLMTALYRLGRQAEALRLYDEAQRLLSDELGVDPGPALQRLHTLVLRQDPSLDAAPETPRPRATPRTAEAATPQPARDDMVGRDQELGRCRAALHRARDGAPAVVVVYGEAGIGKTRLVEEVTRDRGDVAWGRCFDHAGSPAFGPWAQVLATLAELRGSGLVTRALTGRGAEAALLLPPHAVPGARPAPVAGAPEVARARLYDAVTAFLEAMAAERPVTVVLEDLHWADPESAELTEYVAATARAGGLALLMTVRTPAEDGGAQGETLLAALARRPGTERVALHGLDTADVRRFAAGRLGTDVDGEAAERLRRRTDGNPFYIAELVRLLGEERQISGRALGTVPTTVRAVIERRLRHLDPATRELLATAAVLGRGFDLRVLGDVAGRTPAEVAAGLDPAATAGILVPDPESPGRWSFAHALVQDTLATVTGPMRRAALHAQVAETLERRHDGDLAAVAASLAHHHAAAGLMGDPARAVSFSLLAAEAAQERLAFGEGRRHLERALDLVSSVPGAAAAELELRARVQLGSLLTLLYGYNAEEVSVQRRRALRLATETGSTEHLLSALWGTWGIALVSGDFPAADAVADEMAAACANDPLMELAYHHARGQIRYHQGRLLEAKGHLERAAELADRHAKAVRLEIFLQHPAVAARSWLAKVLALMGDTAASDEAARMAEVRNRAVGDPYTATYIDILEGWRAVFLDRPEDALRHGEHGYAVAEEHGFAQLVAFSLVPRGWGRARHGRTAEGATDIERAIAIFSSQPTGHMFGPIMAYALADALRVAGRTEEALETTEAGIAEGERIGERFFLAGLYLQRAELTGDGAHDRERAAGIAREQSAGLFLRGRE
>NC_017093.1|WP_041830191.1|7030503_7036830_-|DUF11-domain-containing-protein
MFAKHARFPLLLALGATAIVAFPPSPARAENDPPPSPSTGGPTLVDLGSLGIAGRGTGRVAEINSKGQVAATVWADRGPRASILEFGARTDLQAALPSGADSSEAVGITDTGLVAGRVSGIGKEFQSFTWKAGRAQVIDPPLARAVNEKGQIAGDAWVRDPDGEVTQLSAFKDQYIEVTAINESGVVAGVADMTPGGGLDTPRAFRTRPGMPINPGKDTLEYLGGRTLAKDVNDRGQVAGYATDSSGGYVPVIWGADGTPTSPRAPRGGTANAINNAGTAVGMMRIADGAPRAALYQNGGTTDLNTLLPPDSGWTLTEANAINDLGQIAGVGRPEGADVDHAFLLDLTKQGPVIESLTLETQTYPSTEWKQVEAAGTVDGNRVRITAKLVNRSEFFAFTQLRIGETVSGKDLPGGTRDEILSPKETVTEEIEWDTAGFAWTDGAKPVSDRVIAAKLVTGGVTRDGRTAPIVIRPKPVILTHGYKSNAEASWGKYAPILTKGHPLLKGYAVGDGQAPGVLNTGNQWKPAAPTNTLAGNAMEQATYIDGIRKATGATHVDIVAHSMGGLISRKYIQDDMPTASDGKPVVNRLIQLGTPNMGSPCADFLMDQTSIGGVRIPRLVPFMPATLQLTPKYITEVFNQGVTNLNGVPVSNLVGTGNRVPCKPYPDGDIVVPVKSAQYIYQDIPWTGVNHLDMTESADDFETYVKPRLASLSAGRNQPKAKAKAPAAAEPEIASGTTFDTPAATVAAGATETLTVDVPEATVFGVTGALPPTIGITLKRSNGTVAARYAPNSDQARQPIQTLAAEYPWADRWTIEVTNAGTEATDVVLSAWVDGNDLTITTDATADDAGKVTLTARAFAGATVAGVLTDEKGERREVTLADRGDGAYGVVTDALPDGAYAVTVQAEKGTDKRITHTSVQVQRPDTREFELNLTPQPGGTATASPQQDKYKVGTRVTITAKADAGRMPIGWTVDGVAKPAGTLTVTMDRDHDVVAKFGRYSITELGALPGGWARNTAAGRLNDKGQIAATAITGVGDGHVDGQRSRAVRWEDGKLTELPMPPCDEAKGACNSYGSGINEAGDVSGSSSVLESSEPGYSNGSHAVVWSNGTAKDLHDNDALQGRQSAAWVLNDNGQVFGNYRPYNARYDSPIMWSKGSLKRLPEYPQFWSPTAINDKGTVTGSYVTASNWMGPYEGLPATYTNGEVTKLPVPECGDESSSTTSGSANDINHRGDIVGSYFCRHQDDMRYSALLWKDGKPIDLGDGHATAINDAGLIAGFAGVGTDRKPALWLDGTQYMLSDLLAMPTCTPTTADPCLNLTSLLDVNSSGQVLARGTTRELRADGRNSTEARSFLLTPTEANADLRIDQAVSHLTPAPGQTVTWTSTVANSGPDAATGVRADVTLPAGVTPQGCETTRGACKVVGNAVRTTISALPVGATATVTVTGKIAADTAENTALVARAQVGSLAVPDPATADNTASTTSTVMPALSRTAFNFADPVRVGRTSWPGSVTLTNRQPDAMKLYTIDTTGPFQHTDTCPVELAPGAQCTVEFTFTPTEVGAARGELRFTTEQGAAPAFTVALTGTGIEADNAPVIEESEEVHKGVTGKPLVLEIPFTDADLDDTHTARVMWGDEPEADAEVVPRRGGGTVRISRTFTEPSEGVVVLTVTDSKKETAYGYVWYAVTRPDANTAPSITAGPDVALTTGERFQRTVTFTDPTSTSWTATADYGDGERHEVPVSDHGLALDHTWAKAGSYPVSVTVTDDGGLSTTARFTATVTAAQTPNTAPKVEFTGAASLTEGGTWTGRGTITDPDADTWTATADFGDGPQPVELNGKSFDLSHLFTDDGSRTVAVRVTDDKGGSATATQVVKVANAAPVITLRTPGQMVATGALLTFEASFTDAGAADTHTASWKIGGKAYEGAVAEANGKGATTLPHLFTKAGRYSVTLTVKDDDDGGTTTSQEIEIMVYDPATSIVGAGVTASPAGSCILGGICGTGSAAGFALHAAYPKKAGTPAGELRYTAAGFELRSSSLTVLAAADGKALLRGTAKANGAEVTFEATATDSGRPLDRTDSLRLVVTSKSGKVIYDNQRSGTKSPVIGVIRISD
>NC_017093.1|WP_014446630.1|7028965_7029553_-|hypothetical-protein
MKDPIDLVGMFGEGWCVTLTRGDVFEALSGMEVDPADCRSASTLAEAAGLTWDTFGVLLVAREIGEGLTLVLEFDGSTGWVGADLDVLALLSAAGGMACSIYKNPHREELLYASGAALITGLDPATFRRWGRVPDRFDDALSAAGFPGPDGEGGSTGILVLPPSKRAVAAMTAITGIAVTPAMFDGPWMAGPSAH
>NC_017093.1|WP_051042610.1|7028366_7028726_-|hypothetical-protein
MRTALGISLLVAGLGVLIQYSVGVPGFPDIPPGPIILGVAGILVLALPRYRWVIVAGLIAALFVTVGGLIEGSVWGRLGEPGRFDVWIGVFMQWAGQAVALVSAVMALTRDHRKAPLPR
>NC_017093.1|WP_172666702.1|7046463_7047954_+|GGDEF-domain-containing-protein
MSQFRAVRAPAEEVERQARELGADELAQRALLLRAAVLLRDGRTGEGGQLAHQVRAWAEQNNVPYVLARAHRELSIFYRAVGDFSEGLTHAVQSVAMLPEDVPGNVRARHLLSLSVALEEGGSPMDGERRAREALALAAAAGDTELTVLVLNNLAYSAFELDDEPSARMLVGQMQEIQQRTGHRFGANEIDTMARVELMGDRFDAVEELLLPVLADQVAANEGDAVAECLLTLALTRRRSGRFDAAQEALDAARVLCAERELAAVSARVREEQAALYAATGRFAEAYEEHRAFHAESSALHSAQRDARARALQAVFEANEARRVSEHFREMAHRDALTGLYNRRYINERVPALLLEAAARRRPLSLAIVDLDHFKRINDTFSHTTGDTVLQHIAELLVEAAGTSGTAARMGGEEFLLIYPGVEADEAAERCERLRLRIRAHGWEPITGAVPVTTSVGVTTTPDGRGTFSALLSQADRNLYAAKRTGRDRVTTDACG
>NC_017093.1|WP_014446642.1|7047964_7048762_+|alpha/beta-fold-hydrolase
MPIFHSRWTTVAGLRTHDRFCTASPGLPVVFVHGLAVSHRYLLPTARALAGRHPVLVPDLPGFGRSDKPPAAWDVTRHGDHLGAWLDTLGLGPVCLAGHSFGAEVVARLAADRPALVAGLVLAGPTADPVARSRSGLIRRFLVDMLVEAPAQAPMIARDALQAGLWRVLATVDHSVRNRIEDDLARLPVRPLILGGELDPIAPLRWRASVTSATGGVAITIPRAAHNVMTTSGRRSADAIAGFLSMGTRRAVPDRSVISPVVPRP
>NC_017093.1|WP_157435146.1|7049091_7050336_+|hypothetical-protein
MALLLRITVAGLAGTSGAATAAGVANAAGAASAAKTASAAKTASAAKTASAAKTASAAGVANAAAPIRAHLASGYAHTCAIRADGGLWCWGSNSSGQLGDGTTTTRATPARVGDATWVAVDAGTGFTCGIRADASLWCWGSNTRGQLGDGTTTRRTTPVQVGAGTDWATVSTGDSHTCAVRTDGTLWCWGFNRLGQLGDGAVVYTATAPQRVDTATTWANVATGYAHTCATRTDGTLWCWGDSSAGQLGLGLLSYRTTPGQVGTLTSWDTLTAGFFSTCATRTDGTLWCWGENGYGQLGVTGIYRTTPVQVGTATDWAGVRAGLDTACGTRIDGSLWCWGNNTSGQLGDGTTTHRYAPVRIGAASDWTADVAAGFHNCAVRASGTLWCWGDNASGQLGDGTTATRPDPRQVTFA
>NC_017093.1|WP_014446644.1|7050391_7050901_-|DUF664-domain-containing-protein
MTIEFPAPTTPAADQAEVFVRYLDYYRETLLSKVAALPAAELRASRLPSGWTPLELVKHLRHVERRWIEWGFQGAPVDDPWADRRDDRWHVGPAESLEQLTAELRAQGEHTTAVARGTALDAIGRPGPRWDGADPASLERILFHLLQEYARHTGHIDIVAELTGGPTGE
>NC_017093.1|WP_014446645.1|7050897_7051671_-|endonuclease/exonuclease/phosphatase-family-protein
MLRFLTWNIRLGGGDRLPAIIEVVKAERPDILAVQELRDFDGYGGRKLTAFAEATGMTAHLSRSVFGQPVAVLVRPPLRITRRSSVRWRLHHAAAAVTVPTAAGPLTVVSTHLNPFSPYRRMREARWLAARHATGSGLTLIAGDLNGLAPAEDHAAALAELPPRYRPRHVSPSGEPDTRAVAAFLEAGFTDLGRTAGTTVPTTGLGGKEFGSMRLDYVLVSPRLASRAGTPQVIRTELTDHASDHYPVRVDLDILGG
>NC_017093.1|WP_014446646.1|7051670_7053143_-|phosphatase-PAP2-family-protein
MDDTRVVERTGWAPVRHFAERSVLGLIAVLAVGLGFGVLLLLVRFHWGPLQDLDRSVADGLNRWASGSETVVAVLQQISSAGGRGFMIPLVALLVLMLIIRRRPRPALYLVVTGLGAMILDPSLKALIGRVRPVVEVPVATAPGNSFPSGHALGSMVVYGMIVLVFLPAVRRRWRPFFIGAAAVIVAAIGFTRIALGVHFLSDVLAGWLLGVAWISATAYAFRMWRREAGHTDPHLTDGLEPEAGPDLRLAPAEGPVLPHPWAKAAEILVGWVFVFGLLYLVGYTVTRWTPGFDTGFVEWLQTFRTERLDKWSWAWSKAGDTHAILFISLIFCPLALALWRQWRPVLFLVLTMVGELTLFLCAAAAVGRPRPPVEQLDGQMPTSSFPSGHIAATMCLWAAIAIITMARIRQPWRWIFPALAVIMPLGVALSRMYRGMHHPTDMLGAAILTTAWLTVLWFTIRPNAHPASATEAASEAVAATDSDRLEPAR
>NC_017093.1|WP_172666703.1|7053161_7054130_-|YihY/virulence-factor-BrkB-family-protein
MSGDELSADDAFVALRHYGRWPLLRDAFIRFRYGDGFSHSRAFALQLCLAIVPFLIALSGLATDLGVESGGQVVADTVIALTPGASEPVVRELLDDGDKTEEAGELALALGMVTGLVALTTAMAQVERGANRIYGVERDRPAIAKYIRAAVLAFTAGLPALFGFLLLVAGRAAGESAEREFGLPGGVRVAWDVVRWPVSLALIVFAVGALFRYSARRKQPALSWLLFGAVVATVLWWIASLLLAGYIRVSDSFGATYGPLTAIMALLLWANLTGVAFFLGLAFAAQLEASRVGARPAQEDQWEPEPDIPAQRAPGVPVEPSG
>NC_017093.1|WP_172666704.1|7054162_7055086_-|diacylglycerol-kinase
MVNPVKVADLDHLRAAVGEALQKAGWPEPRWYETTPEDPGRGQAKKAMADGAELVFACGGDGTVTAVVTALAGTRTALAVLPAGTGNLLAANLGLGTDPATGLQVALEGGRRRIDVGMIDDRCFVVMAGMGFDAQMLEDTSETAKRRIGWLAYVGGAAKHLLDRPMRARIRLDGGAPMPRHPRAIIVGNVGRLQGGVRLLSKAEPDDGKLNVAILSPANLAHWAALAWAVLRRQDRVPLMETYTASRVEIYSNRAQPRQLDGDLIAPGKVMKIHVRPKALLLCVPQPDADPDLAEDAGAVADRAEQL
>NC_017093.1|WP_014446649.1|7055177_7055666_+|DUF1990-domain-containing-protein
MTELTYPHVGATRTGPLPAGYRHLRYRTRIGAGEAVLTRAGEAILTFAMHRATGARIVADAGRAAPGVRLTVGLGPLRAPCEVVWVSEHGFGYGTRPGHPATGEEAFQVEIDDRGDVWFTVTAFSRPAGTLMRLGGPVAVGFQHLYARLCGRALRRVSTVTS
>NC_017093.1|WP_014446650.1|7055662_7056439_+|MBL-fold-metallo-hydrolase
MSTTSVTWWGHSTVWLADSGVTLLTDPVLTDRLAHLRRMAGPTPSLPGAPDAVLLSHLHADHFHAASLKAVPGSPLLVVPRGAGSFTAKALGRAAAQRVIEVAPGEETTIAGVRVRAVPARHDGGRGPWSRERAVALGYVIEGSARTWFAGDTGLFDEMSSIGPLDLALIPVGGWGPTLGAHGHLDAVDAAEALRRVKTAWAVPVHYGTLWPAGMGRIRRHMFDEPGARFAEHAARTSPETRVRVLAHGETLTVGPAA

Crispr_ID: NC_017093_24

• CRISPR_ID: NC_017093_24
• CRISPR_location: 7049119-7049243
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_017093_24

Consensus_repeat	Method
GCCAGCGCAGCCAAGACGGCCAGCGC	CRISPRCasFinder

spacers of NC_017093_24

>24.1|7049145|19|NC_017093|CRISPRCasFinder
AGCCACCGCCGCCGGGGTA
>24.2|7049190|28|NC_017093|CRISPRCasFinder
AGCCAAGACGGCCAGCGCAGCCAAGACG

CRISPR arrays and Neighbor proteins around NC_017093_24

CRISPR arrays

The CRISPR arrays of NC_017093_24

>merge|NC_017093|24|7049119-7049243|CRISPRCasFinder
GCCGGCCTCGCCGGGACGTCCGGCGCAGCCACCGCCGCCGGGGTAGCGAACGCGGCCGGCGCCGCCAGCGCAGCCAAGACGGCCAGCGCAGCCAAGACGGCCAGCGCAGCCAAGACGGCCAGCGC

>NC_017093|24|23|7049119-7049243|CRISPRCasFinder
GCCGGCCTCGCCGGGACGTCCGGCGC	AGCCACCGCCGCCGGGGTA
GCGAACGCGGCCGGCGCCGCCAGCGC	AGCCAAGACGGCCAGCGCAGCCAAGACG
GCCAGCGCAGCCAAGACGGCCAGCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_014446642.1|7047964_7048762_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|184875
NC_017093.1|WP_014446638.1|7043569_7043752_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014446649.1|7055177_7055666_+|DUF1990-domain-containing-protein	unknown	unknown	gnl|CDD|378157
NC_017093.1|WP_014446636.1|7042026_7042893_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|225117
NC_017093.1|WP_172666704.1|7054162_7055086_-|diacylglycerol-kinase	unknown	unknown	gnl|CDD|224513
NC_017093.1|WP_014446652.1|7057026_7057935_-|serine-hydrolase	unknown	unknown	gnl|CDD|379138
NC_017093.1|WP_014446635.1|7041388_7041820_+|SsgA-family-sporulation/cell-division-regulator	unknown	unknown	gnl|CDD|377399
NC_017093.1|WP_014446650.1|7055662_7056439_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|225130
NC_017093.1|WP_157435500.1|7056476_7057079_+|VTT-domain-containing-protein	unknown	unknown	gnl|CDD|223659
NC_017093.1|WP_014446645.1|7050897_7051671_-|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl|CDD|377028
NC_017093.1|WP_172666703.1|7053161_7054130_-|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl|CDD|377085
NC_017093.1|WP_014446639.1|7043737_7044652_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014446640.1|7044717_7046295_+|fibronectin-type-III-domain-containing-protein	unknown	unknown	gnl|CDD|223021
NC_017093.1|WP_172666702.1|7046463_7047954_+|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|143635
NC_017093.1|WP_014446633.1|7037038_7040197_-|AfsR/SARP-family-transcriptional-regulator	unknown	unknown	gnl|CDD|274846
NC_017093.1|WP_014446644.1|7050391_7050901_-|DUF664-domain-containing-protein	unknown	unknown	gnl|CDD|368218
NC_017093.1|WP_041830193.1|7040704_7041112_-|TIGR02611-family-protein	unknown	unknown	gnl|CDD|131660
NC_017093.1|WP_014446637.1|7042973_7043429_+|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl|CDD|273242
NC_017093.1|WP_157435147.1|7058107_7059040_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014446646.1|7051670_7053143_-|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239486

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_014446642.1|7047964_7048762_+|alpha/beta-fold-hydrolase	gnl|CDD|184875	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional.	6.57133e-16
NC_017093.1|WP_014446650.1|7055662_7056439_+|MBL-fold-metallo-hydrolase	gnl|CDD|225130	COG2220, COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only].	4.07566e-36
NC_017093.1|WP_014446649.1|7055177_7055666_+|DUF1990-domain-containing-protein	gnl|CDD|378157	pfam09348, DUF1990, Domain of unknown function (DUF1990). This family of proteins are functionally uncharacterized.	6.41681e-58
NC_017093.1|WP_014446636.1|7042026_7042893_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	2.32614e-22
NC_017093.1|WP_172666704.1|7054162_7055086_-|diacylglycerol-kinase	gnl|CDD|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	2.9007e-43
NC_017093.1|WP_014446652.1|7057026_7057935_-|serine-hydrolase	gnl|CDD|379138	pfam13354, Beta-lactamase2, Beta-lactamase enzyme family. This family is closely related to Beta-lactamase, pfam00144, the serine beta-lactamase-like superfamily, which contains the distantly related pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	5.60232e-14
NC_017093.1|WP_014446635.1|7041388_7041820_+|SsgA-family-sporulation/cell-division-regulator	gnl|CDD|377399	pfam04686, SsgA, Streptomyces sporulation and cell division protein, SsgA. The precise function of SsgA is unknown. It has been found to be essential for spore formation, and to stimulate cell division.	7.1959e-40
NC_017093.1|WP_157435500.1|7056476_7057079_+|VTT-domain-containing-protein	gnl|CDD|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	3.82693e-17
NC_017093.1|WP_172666702.1|7046463_7047954_+|GGDEF-domain-containing-protein	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.19243e-53
NC_017093.1|WP_172666703.1|7053161_7054130_-|YihY/virulence-factor-BrkB-family-protein	gnl|CDD|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	2.80938e-31
NC_017093.1|WP_014446640.1|7044717_7046295_+|fibronectin-type-III-domain-containing-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	0.000275427
NC_017093.1|WP_014446645.1|7050897_7051671_-|endonuclease/exonuclease/phosphatase-family-protein	gnl|CDD|377028	pfam03372, Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. This family includes: AP endonuclease proteins EC:4.2.99.18, DNase I proteins EC:3.1.21.1, Synaptojanin an inositol-1,4,5-trisphosphate phosphatase EC:3.1.3.56, Sphingomyelinase EC:3.1.4.12, and Nocturnin.	3.2216e-17
NC_017093.1|WP_014446633.1|7037038_7040197_-|AfsR/SARP-family-transcriptional-regulator	gnl|CDD|274846	TIGR03903, TOMM_kin_cyc, TOMM system kinase/cyclase fusion protein. This model represents proteins of 1350 in length, in multiple species of Burkholderia, in Acidovorax avenae subsp. citrulli AAC00-1 and Delftia acidovorans SPH-1, and in multiple copies in Sorangium cellulosum, in genomic neighborhoods that include a cyclodehydratase/docking scaffold fusion protein (TIGR03882) and a member of the thiazole/oxazole modified metabolite (TOMM) precursor family TIGR03795. It has a kinase domain in the N-terminal 300 amino acids, followed by a cyclase homology domain, followed by regions without named domain definitions. It is a probable bacteriocin-like metabolite biosynthesis protein. [Cellular processes, Toxin production and resistance].	1.00184e-44
NC_017093.1|WP_014446644.1|7050391_7050901_-|DUF664-domain-containing-protein	gnl|CDD|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	7.63263e-31
NC_017093.1|WP_041830193.1|7040704_7041112_-|TIGR02611-family-protein	gnl|CDD|131660	TIGR02611, Putative_membrane_protein, TIGR02611 family protein. Members of this family are Actinobacterial putative proteins of about 150 amino acids in length with three apparent transmembrane helix and an unusual motif with consensus sequence PGPGW. [Hypothetical proteins, Conserved].	6.11098e-19
NC_017093.1|WP_014446637.1|7042973_7043429_+|Rrf2-family-transcriptional-regulator	gnl|CDD|273242	TIGR00738, Putative_HTH-type_transcriptional_regulator, Rrf2 family protein. This model represents a superfamily of probable transcriptional regulators. One member, RRF2 of Desulfovibrio vulgaris is an apparent regulatory protein experimentally (MEDLINE:97293189). The N-terminal region appears related to the DNA-binding biotin repressor region of the BirA bifunctional according to results after three rounds of PSI-BLAST with a fairly high stringency. [Unknown function, General].	1.23669e-34
NC_017093.1|WP_014446646.1|7051670_7053143_-|phosphatase-PAP2-family-protein	gnl|CDD|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	4.40397e-37

Protein sequences

>NC_017093.1|WP_014446642.1|7047964_7048762_+|alpha/beta-fold-hydrolase
MPIFHSRWTTVAGLRTHDRFCTASPGLPVVFVHGLAVSHRYLLPTARALAGRHPVLVPDLPGFGRSDKPPAAWDVTRHGDHLGAWLDTLGLGPVCLAGHSFGAEVVARLAADRPALVAGLVLAGPTADPVARSRSGLIRRFLVDMLVEAPAQAPMIARDALQAGLWRVLATVDHSVRNRIEDDLARLPVRPLILGGELDPIAPLRWRASVTSATGGVAITIPRAAHNVMTTSGRRSADAIAGFLSMGTRRAVPDRSVISPVVPRP
>NC_017093.1|WP_172666702.1|7046463_7047954_+|GGDEF-domain-containing-protein
MSQFRAVRAPAEEVERQARELGADELAQRALLLRAAVLLRDGRTGEGGQLAHQVRAWAEQNNVPYVLARAHRELSIFYRAVGDFSEGLTHAVQSVAMLPEDVPGNVRARHLLSLSVALEEGGSPMDGERRAREALALAAAAGDTELTVLVLNNLAYSAFELDDEPSARMLVGQMQEIQQRTGHRFGANEIDTMARVELMGDRFDAVEELLLPVLADQVAANEGDAVAECLLTLALTRRRSGRFDAAQEALDAARVLCAERELAAVSARVREEQAALYAATGRFAEAYEEHRAFHAESSALHSAQRDARARALQAVFEANEARRVSEHFREMAHRDALTGLYNRRYINERVPALLLEAAARRRPLSLAIVDLDHFKRINDTFSHTTGDTVLQHIAELLVEAAGTSGTAARMGGEEFLLIYPGVEADEAAERCERLRLRIRAHGWEPITGAVPVTTSVGVTTTPDGRGTFSALLSQADRNLYAAKRTGRDRVTTDACG
>NC_017093.1|WP_014446640.1|7044717_7046295_+|fibronectin-type-III-domain-containing-protein
MRYMAPPLAELTAQAQTLSSAGDLAGARALLDRVLRDANADPRRATADLAIAAALHARVLIALGDPQAARLWAAFAHAAEERLHGARDERTIAAAATHAAVLQRIGQHGRAALVYNDLVGELARLDGPQAPRVLAAEADLAIAEHAAGHCGPARARLARAWRLHREAHGDAAPAGIKMLARLGAMERECGRDAEAAEHLALAQELSSRYLPSDHPLARQAARLSSAKPSGRHACGATEQPGGQTGGTPFRPFPRRPTVSDPGPVTPPPYPAEAPGMPPPDDRPTDPRGTVYPIEGDEMPPPDNRPTDPNGTVYQQPLYLSDVHRLPGDLTGRHARADTPPPLPGHRAPDYDEEGKPAPVGTALPVPTEEPRRNRPAHPLLLAAALAGGVAAAAAVVILTLPDADGATGQQAAPPASAPLASAPAASAPVEKTTAAGEPGAPQNLRLRDNGDSVSLEWVYPKGAGGPVHVAAGKDGAEPRKFQELPAGAADYMVYSLSSTANYCFRVAVEYSADRIADSAPVCTNR
>NC_017093.1|WP_014446639.1|7043737_7044652_-|hypothetical-protein
MSPIGTVKRELLVRHLQAWAAGALHRARRATYVHGYADADGGAAAETAVRVLADLPDLARGRELSMVALGDDVTGVGERLVAAQREAGTASGLAVLPVGGGTDARLAVALKAAGASHVPLLAFLDAASAGEPPAAATVAAVAAGKPAEVLLALAPGVAVEPYRRIGFPLVTAAELATGEEPGEVLVFATTSGKSLESFKEALWAVDEFAGVRLRDPGDPERHLIDISLTPHPGPLRRELLAHLSGVGAATVTDLRTFTMTETVYRAADATRVLHTLVDAGTVTRRPEHGRLGGDVEISLPSPAA
>NC_017093.1|WP_014446638.1|7043569_7043752_+|hypothetical-protein
MGLVFRSRKKFGPLILNFTENGYSSWSLKIGRWSWNSRTRAHRVDLPGPMSWKQDKSRSR
>NC_017093.1|WP_014446637.1|7042973_7043429_+|Rrf2-family-transcriptional-regulator
MQISARGDYAVRAALSLAQAYPALMSAQAIAQEQEMPRKFLEAVLADLRRAGVVRAQRGAEGGYTLSHPPRDVAVGQIIRAVDGPLAGVRGLRPEETQYTGAAENLPSLWVAVRAAVREVLDEVSLAELLSGKMPAHVRKLTTRPDAWQPR
>NC_017093.1|WP_014446636.1|7042026_7042893_+|helix-turn-helix-transcriptional-regulator
MPAMTSADTAHAYTLPDWAGISGCALPVTAGAVTGLLAHHALLLTVTGPLVAEVDFTVHRCEPGTLLWIRPGQALRVEPGKHESTTIVFRPGLFGPDDLPGLAPDDPGGPARHPIPLTGSAEFDSLVRDAAGPPGTTAAALLRHELAALLLRLSLLDPAPESPGHVESRTFERFRRRLEAGYPQTRRVEDYAAELGCSVRTLTRASLAITGRTAKQVVDDRVALQARRLLAATSLSVAEVGRNLGFGEPTNFGRFFHRETGLSPGQFRGRYVDEPSGGGIPAQRRPSD
>NC_017093.1|WP_014446635.1|7041388_7041820_+|SsgA-family-sporulation/cell-division-regulator
MSTIRPTTVEVETSLRLVAPDATALPVRASLRYDPADPYAVHVLFHAESAGGEAVSWSFARELLVTGLDEPAGIGDVRVWPWATPRGDFVALALSSPDGNALFEVPRSVLVRFLRRTYVVVPRGRESDHLDVDAAVNRLLAGR
>NC_017093.1|WP_041830193.1|7040704_7041112_-|TIGR02611-family-protein
MGPKTDDGASDVRVLDRIRSNSTGRLALKIGVGVVGGLVVAVGIVLIPFPGPGWAIVILGLAILAIEFHWARGVLEFTKRHVQNWTHWIGRQSLPIRALVGLVGLIFIWAVVWASVRISFGVDLVQVALDWLKAR
>NC_017093.1|WP_014446633.1|7037038_7040197_-|AfsR/SARP-family-transcriptional-regulator
MVRDDHGRRAGWDNVRFEVLGPFQVRDGERVVDIGRPQHRAVLAALLIDAGRVVPAEVLLGRVWGEQPGAGGTASLYACISRLRKRLGPIIVTQAPGYRLDVAGRDIDAVRFSELVSAARRAIAAGRPEDARAHVTEALALHRGTPYGGIRSDFAAHEVSRLEDQVLAATELAAELDLTLGREADLVTWLPDTVAAHPLREGMRGTLMTALYRLGRQAEALRLYDEAQRLLSDELGVDPGPALQRLHTLVLRQDPSLDAAPETPRPRATPRTAEAATPQPARDDMVGRDQELGRCRAALHRARDGAPAVVVVYGEAGIGKTRLVEEVTRDRGDVAWGRCFDHAGSPAFGPWAQVLATLAELRGSGLVTRALTGRGAEAALLLPPHAVPGARPAPVAGAPEVARARLYDAVTAFLEAMAAERPVTVVLEDLHWADPESAELTEYVAATARAGGLALLMTVRTPAEDGGAQGETLLAALARRPGTERVALHGLDTADVRRFAAGRLGTDVDGEAAERLRRRTDGNPFYIAELVRLLGEERQISGRALGTVPTTVRAVIERRLRHLDPATRELLATAAVLGRGFDLRVLGDVAGRTPAEVAAGLDPAATAGILVPDPESPGRWSFAHALVQDTLATVTGPMRRAALHAQVAETLERRHDGDLAAVAASLAHHHAAAGLMGDPARAVSFSLLAAEAAQERLAFGEGRRHLERALDLVSSVPGAAAAELELRARVQLGSLLTLLYGYNAEEVSVQRRRALRLATETGSTEHLLSALWGTWGIALVSGDFPAADAVADEMAAACANDPLMELAYHHARGQIRYHQGRLLEAKGHLERAAELADRHAKAVRLEIFLQHPAVAARSWLAKVLALMGDTAASDEAARMAEVRNRAVGDPYTATYIDILEGWRAVFLDRPEDALRHGEHGYAVAEEHGFAQLVAFSLVPRGWGRARHGRTAEGATDIERAIAIFSSQPTGHMFGPIMAYALADALRVAGRTEEALETTEAGIAEGERIGERFFLAGLYLQRAELTGDGAHDRERAAGIAREQSAGLFLRGRE
>NC_017093.1|WP_014446644.1|7050391_7050901_-|DUF664-domain-containing-protein
MTIEFPAPTTPAADQAEVFVRYLDYYRETLLSKVAALPAAELRASRLPSGWTPLELVKHLRHVERRWIEWGFQGAPVDDPWADRRDDRWHVGPAESLEQLTAELRAQGEHTTAVARGTALDAIGRPGPRWDGADPASLERILFHLLQEYARHTGHIDIVAELTGGPTGE
>NC_017093.1|WP_014446645.1|7050897_7051671_-|endonuclease/exonuclease/phosphatase-family-protein
MLRFLTWNIRLGGGDRLPAIIEVVKAERPDILAVQELRDFDGYGGRKLTAFAEATGMTAHLSRSVFGQPVAVLVRPPLRITRRSSVRWRLHHAAAAVTVPTAAGPLTVVSTHLNPFSPYRRMREARWLAARHATGSGLTLIAGDLNGLAPAEDHAAALAELPPRYRPRHVSPSGEPDTRAVAAFLEAGFTDLGRTAGTTVPTTGLGGKEFGSMRLDYVLVSPRLASRAGTPQVIRTELTDHASDHYPVRVDLDILGG
>NC_017093.1|WP_014446646.1|7051670_7053143_-|phosphatase-PAP2-family-protein
MDDTRVVERTGWAPVRHFAERSVLGLIAVLAVGLGFGVLLLLVRFHWGPLQDLDRSVADGLNRWASGSETVVAVLQQISSAGGRGFMIPLVALLVLMLIIRRRPRPALYLVVTGLGAMILDPSLKALIGRVRPVVEVPVATAPGNSFPSGHALGSMVVYGMIVLVFLPAVRRRWRPFFIGAAAVIVAAIGFTRIALGVHFLSDVLAGWLLGVAWISATAYAFRMWRREAGHTDPHLTDGLEPEAGPDLRLAPAEGPVLPHPWAKAAEILVGWVFVFGLLYLVGYTVTRWTPGFDTGFVEWLQTFRTERLDKWSWAWSKAGDTHAILFISLIFCPLALALWRQWRPVLFLVLTMVGELTLFLCAAAAVGRPRPPVEQLDGQMPTSSFPSGHIAATMCLWAAIAIITMARIRQPWRWIFPALAVIMPLGVALSRMYRGMHHPTDMLGAAILTTAWLTVLWFTIRPNAHPASATEAASEAVAATDSDRLEPAR
>NC_017093.1|WP_172666703.1|7053161_7054130_-|YihY/virulence-factor-BrkB-family-protein
MSGDELSADDAFVALRHYGRWPLLRDAFIRFRYGDGFSHSRAFALQLCLAIVPFLIALSGLATDLGVESGGQVVADTVIALTPGASEPVVRELLDDGDKTEEAGELALALGMVTGLVALTTAMAQVERGANRIYGVERDRPAIAKYIRAAVLAFTAGLPALFGFLLLVAGRAAGESAEREFGLPGGVRVAWDVVRWPVSLALIVFAVGALFRYSARRKQPALSWLLFGAVVATVLWWIASLLLAGYIRVSDSFGATYGPLTAIMALLLWANLTGVAFFLGLAFAAQLEASRVGARPAQEDQWEPEPDIPAQRAPGVPVEPSG
>NC_017093.1|WP_172666704.1|7054162_7055086_-|diacylglycerol-kinase
MVNPVKVADLDHLRAAVGEALQKAGWPEPRWYETTPEDPGRGQAKKAMADGAELVFACGGDGTVTAVVTALAGTRTALAVLPAGTGNLLAANLGLGTDPATGLQVALEGGRRRIDVGMIDDRCFVVMAGMGFDAQMLEDTSETAKRRIGWLAYVGGAAKHLLDRPMRARIRLDGGAPMPRHPRAIIVGNVGRLQGGVRLLSKAEPDDGKLNVAILSPANLAHWAALAWAVLRRQDRVPLMETYTASRVEIYSNRAQPRQLDGDLIAPGKVMKIHVRPKALLLCVPQPDADPDLAEDAGAVADRAEQL
>NC_017093.1|WP_014446649.1|7055177_7055666_+|DUF1990-domain-containing-protein
MTELTYPHVGATRTGPLPAGYRHLRYRTRIGAGEAVLTRAGEAILTFAMHRATGARIVADAGRAAPGVRLTVGLGPLRAPCEVVWVSEHGFGYGTRPGHPATGEEAFQVEIDDRGDVWFTVTAFSRPAGTLMRLGGPVAVGFQHLYARLCGRALRRVSTVTS
>NC_017093.1|WP_014446650.1|7055662_7056439_+|MBL-fold-metallo-hydrolase
MSTTSVTWWGHSTVWLADSGVTLLTDPVLTDRLAHLRRMAGPTPSLPGAPDAVLLSHLHADHFHAASLKAVPGSPLLVVPRGAGSFTAKALGRAAAQRVIEVAPGEETTIAGVRVRAVPARHDGGRGPWSRERAVALGYVIEGSARTWFAGDTGLFDEMSSIGPLDLALIPVGGWGPTLGAHGHLDAVDAAEALRRVKTAWAVPVHYGTLWPAGMGRIRRHMFDEPGARFAEHAARTSPETRVRVLAHGETLTVGPAA
>NC_017093.1|WP_157435500.1|7056476_7057079_+|VTT-domain-containing-protein
MAELGTIASLFAIVAFGAIVPVVPTGAAVSGAAALAFHTQPLTIVLVLIAGAAGAYVGDLVMYAMCRLGGESLARRLRWLRDEQRLASVKHRLEEKQVPVLLVSRLIPGGRVPVLLAAAFVGLPWRTFVVANVPACALWSVVYAAIGLAGGSIFPEPWQGVIAAVVLILIVNQSMTWFSRRRSVNTSNASGLASPPSPPP
>NC_017093.1|WP_014446652.1|7057026_7057935_-|serine-hydrolase
MVAAAGILGGGVLVARGMTGDGSAASAVPLAGAFKQAPPAAAPKPSASPTPTGPSPEELAAQERAKRVKALNAALKKYAATVPEFSVAVLDKTTGEAYSYRGDEKYETASVVKVQVLACLLLTAQDRGRKVTSSEDALAKKMIRYSDNAATTSLFSKLGRASAISACNKRLGLTQTRVSSSWGLTRTTVKDQVKLLDALVDEKGELTAASRKYADTLMSTVAEDQDWGVPAVAKAGEEATVKNGWLSRSTENGRWIINSVGRITDDDTDVSIAVLSHLNKTMPSGITVVEKAAKLTRTHLKY
>NC_017093.1|WP_157435147.1|7058107_7059040_+|hypothetical-protein
MAILSALTRAALAAPAAAADLTRSAIGQVIETAATAATIPVRAVGLISQAELLLNRVNLVAGEAEDLIGRVSTAVAQAEELITKVTLVANSAETTVGDARAIATAAALTIEEAATISSAAGDLVRRASVTAEAAGVVVGDAAAALGEVGAITTAAKSAVGEVSSITTAASGTIAEVAGLTDSARGIVTSASGVADQAEAVVGRADALTGEVEVLLNGYAPTLRQAAPLAARFVAELTPDEVTAAIRMVDQLPQLRDHLVNDVMPLLGKLDQVGPDLHKLLEVTEDLHLAIAGLPGLKLLRRRGEERVHDA

Crispr_ID: NC_017093_26

• CRISPR_ID: NC_017093_26
• CRISPR_location: 8478333-8478394
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_26

Consensus_repeat	Method
AGCGGCAACGACCGGATCGTCGG	CRISPRCasFinder

spacers of NC_017093_26

>26.1|8478356|16|NC_017093|CRISPRCasFinder
GTCCAGCCTCAGCAGT

CRISPR arrays and Neighbor proteins around NC_017093_26

CRISPR arrays

The CRISPR arrays of NC_017093_26

>merge|NC_017093|26|8478333-8478394|CRISPRCasFinder
GCCGGCAACGACCGGTTCCTGCAGTCCAGCCTCAGCAGTGGCGACGACGACCTCTTCGTCGG

>NC_017093|26|25|8478333-8478394|CRISPRCasFinder
GCCGGCAACGACCGGTTCCTGCA	GTCCAGCCTCAGCAGT
GGCGACGACGACCTCTTCGTCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_157435209.1|8490794_8491658_+|hypothetical-protein	unknown	unknown	gnl|CDD|380807
NC_017093.1|WP_014447953.1|8485848_8486442_-|recombination-protein-RecR	unknown	unknown	gnl|CDD|234616
NC_017093.1|WP_014447946.1|8474996_8477303_+|calcium-binding-protein	unknown	unknown	gnl|CDD|380205
NC_017093.1|WP_041830338.1|8482577_8484362_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173871
NC_017093.1|WP_014447948.1|8479349_8480387_-|dipeptide-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|236898
NC_017093.1|WP_014447937.1|8467383_8467908_+|orotate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234771
NC_017093.1|WP_014447943.1|8472177_8473902_+|2-isopropylmalate-synthase	unknown	unknown	gnl|CDD|235154
NC_017093.1|WP_014447957.1|8491993_8492293_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014447940.1|8468750_8469815_-|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|237845
NC_017093.1|WP_157435554.1|8474119_8474590_+|DUF1524-domain-containing-protein	unknown	unknown	gnl|CDD|377857
NC_017093.1|WP_014447936.1|8466969_8467245_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014447941.1|8469823_8471089_-|aspartate-kinase	unknown	unknown	gnl|CDD|235843
NC_017093.1|WP_014447955.1|8486911_8490052_-|DNA-polymerase-III-subunit-gamma-and-tau	unknown	unknown	gnl|CDD|236090
NC_017093.1|WP_014447939.1|8468433_8468754_-|divalent-cation-tolerance-protein-CutA	unknown	unknown	gnl|CDD|376987
NC_017093.1|WP_014447952.1|8484436_8485444_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NC_017093.1|WP_014447949.1|8480405_8481446_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|223521
NC_017093.1|WP_157435556.1|8474484_8474850_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_041831682.1|8471263_8471992_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014447954.1|8486445_8486769_-|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl|CDD|234669
NC_017093.1|WP_014447950.1|8481457_8482459_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_157435209.1|8490794_8491658_+|hypothetical-protein	gnl|CDD|380807	cd20237, PFM_LIN24-like, pore-forming module of Caenorhabditis elegans LIN-24 and similar aerolysin-type beta-barrel pore-forming proteins. The process of cytotoxic cell death occurs in Caenorhabditis elegans containing mutations in either of lin-24 and lin-33. The cytotoxicity caused by mutation of either gene requires the function of the other. Genes required for the engulfment of apoptotic corpses function in the cytotoxic cell deaths induced by mutations in lin-24 and lin-33. It has been proposed that Caenorhabditis elegans LIN-24 may function to interact with bacterial toxins having similarity with it, and inactivate these, thereby allowing C. elegans to consume or survive exposure to bacteria that produce such toxins. Members of this group belong to the aerolysin family of beta-pore-forming proteins (beta-PFPs). PFPs are generally secreted as water-soluble monomers, which upon binding to target lipid membranes, oligomerize and form transmembrane pores harmful to cells. Beta-PFPs form pores by transmembrane beta-barrels. Aerolysin-type beta-PFPs are believed to use an amphipathic beta-hairpin to form the beta-barrel, are found in all kingdoms of life and many are bacterial toxins. In addition to having a role in microbial infection, they have potential as biotechnological sensors and delivery systems. They share a similar monomeric architecture, with a variable membrane-binding domain and a structurally conserved pore-forming region. A significant portion of the monomeric subunit structure is re-organized to form the pore. Oligomers formed by members of the aerolysin family include: hepta- (aerolysin), octa- (Dln1), and nonameric oligomers (lysenin and monalysin).	0.00744822
NC_017093.1|WP_014447953.1|8485848_8486442_-|recombination-protein-RecR	gnl|CDD|234616	PRK00076, recR, recombination protein RecR; Reviewed.	3.28459e-114
NC_017093.1|WP_014447946.1|8474996_8477303_+|calcium-binding-protein	gnl|CDD|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	1.6739e-16
NC_017093.1|WP_041830338.1|8482577_8484362_-|ABC-transporter-substrate-binding-protein	gnl|CDD|173871	cd08506, PBP2_clavulanate_OppA2, The substrate-binding domain of an oligopeptide binding protein (OppA2) from the biosynthesis pathway of the beta-lactamase inhibitor clavulanic acid contains the type 2 periplasmic binding fold. Clavulanic acid (CA), a clinically important beta-lactamase inhibitor, is one of a family of clavams produced as secondary metabolites by fermentation of Streptomyces clavuligeru. The biosynthesis of CA proceeds via multiple steps from the precursors, glyceraldehyde-3-phosphate and arginine. CA possesses a characteristic (3R,5R) stereochemistry essential for reaction with penicillin-binding proteins and beta-lactamases. Two genes (oppA1 and oppA2) in the clavulanic acid gene cluster encode oligopeptide-binding proteins that are required for CA biosynthesis. OppA1/2 is involved in the binding and transport of peptides across the cell membrane of Streptomyces clavuligerus. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	2.46662e-160
NC_017093.1|WP_014447937.1|8467383_8467908_+|orotate-phosphoribosyltransferase	gnl|CDD|234771	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated.	9.86158e-43
NC_017093.1|WP_014447943.1|8472177_8473902_+|2-isopropylmalate-synthase	gnl|CDD|235154	PRK03739, PRK03739, 2-isopropylmalate synthase; Validated.	0
NC_017093.1|WP_014447940.1|8468750_8469815_-|aspartate-semialdehyde-dehydrogenase	gnl|CDD|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	3.79724e-155
NC_017093.1|WP_157435554.1|8474119_8474590_+|DUF1524-domain-containing-protein	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	1.3374e-11
NC_017093.1|WP_014447948.1|8479349_8480387_-|dipeptide-ABC-transporter-ATP-binding-protein	gnl|CDD|236898	PRK11308, dppF, dipeptide transporter ATP-binding subunit; Provisional.	1.00317e-154
NC_017093.1|WP_014447941.1|8469823_8471089_-|aspartate-kinase	gnl|CDD|235843	PRK06635, PRK06635, aspartate kinase; Reviewed.	0
NC_017093.1|WP_014447955.1|8486911_8490052_-|DNA-polymerase-III-subunit-gamma-and-tau	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0
NC_017093.1|WP_014447939.1|8468433_8468754_-|divalent-cation-tolerance-protein-CutA	gnl|CDD|376987	pfam03091, CutA1, CutA1 divalent ion tolerance protein. Several gene loci with a possible involvement in cellular tolerance to copper have been identified. One such locus in eubacteria and archaebacteria, cutA, is thought to be involved in cellular tolerance to a wide variety of divalent cations other than copper. The cutA locus consists of two operons, of one and two genes. The CutA1 protein is a cytoplasmic protein, encoded by the single-gene operon and has been linked to divalent cation tolerance. It has no recognized structural motifs. This family also contains putative proteins from eukaryotes (human and Drosophila).	1.26893e-38
NC_017093.1|WP_014447949.1|8480405_8481446_-|ABC-transporter-ATP-binding-protein	gnl|CDD|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.47363e-174
NC_017093.1|WP_014447952.1|8484436_8485444_-|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.05333e-91
NC_017093.1|WP_014447954.1|8486445_8486769_-|YbaB/EbfC-family-nucleoid-associated-protein	gnl|CDD|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	2.4109e-39
NC_017093.1|WP_014447950.1|8481457_8482459_-|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	9.66918e-103

Protein sequences

>NC_017093.1|WP_014447946.1|8474996_8477303_+|calcium-binding-protein
MSRSQWLTRIGVALFTTIAVGAVGTPAFAASTGTASVSGKSTVVFKAGSGRTNSVKITRSLRTITIDDKVAVKAGKGCKPVKGDKTKVRCTPYMTPTLVRAYLGDRNDVLVSTAGTPLKAYGGSGDDKITGSSGADRLVGDSGNDQIWGAAGNDSLDGGTGNDRVKGGTGNDKLYGSAGNDTVNGESGNDSLDGGSGNDSIAGSTGNDNELGGTGNDTFVQGGNGRADRDVIRGQAGRDTVSYATRTGTVWISTDTTKADDGEAGERDTVHPDIEVLVGGRGADFLRGGGNATAFYGGDGNDHLVASAHHSLLDGGNGRDRVFGGQGNDTLRGGNDNDELIGWSGNDLLDGGNGDDYLAGDDPDLESSSARGNDVLRGGPGSDRVDYNGNSKPVTVDLDGATGDDGQAGEHDTVGSDVERLIGSPQSDVLTGNSAANHIVGGFGDDVIRGGGGNDTLSGEDGADRVFGETGDDTLQGGNGNDVLTGDSGNDKEYGDAGDDTFRQPQASGADADTFAGGTGTDFVDYSYRTTSSVTLSLNGVKGDDGGDSEGDTLPADVEVLAGSALGGDTIRGSSGNDTLHGCGFGDKIYGEGGDDVIHGEGVCSATAERDSIEPQGSYLVGGAGDDKITGTKYSDRFFGDYDTPSDTPRPAGVDTLIGTSGSNGSDYDDDAADYRYASGPVITGNVPTGKTGERDKLSGISIVFGSEFDDVLALDADYHWVYDPTLYGLGGDDELYGGTATWLNGGDGTDLCRLSETSTGEKRNCEL
>NC_017093.1|WP_157435556.1|8474484_8474850_+|hypothetical-protein
MVHVRQGLGNREDLLEADRHREGEGGARRHAGDLLMASPEKSLTTDIVPGPGGVMTDEVGVVTGDLTLRTEISGGDVVLRVQYKDAEEWYAVTGGKAPLADPADLEAVHSIAVGLLNRPGG
>NC_017093.1|WP_157435554.1|8474119_8474590_+|DUF1524-domain-containing-protein
MKGYTREKFPHWRDTGSNCDVRDSVLERDGEKVKRSGCNVVAGTWRSLYDGEVLNSPTKVDIDHMVPLANAWRSGAAKWDNDKRGDFANDLERPQLIAVSASSNRSKGDQDPSTWKPSDRDSWCTYAKDWVTVKTYWKLTVTEKEKVALDDMLETC
>NC_017093.1|WP_014447943.1|8472177_8473902_+|2-isopropylmalate-synthase
MSDAFKTQAPSAMPFQRYEAYQKQFDVPLTDRQWPSRVVETAPRWCAVDLRDGNQALIDPMSPERKRRMFMLLVKMGYKEIEVGFPAASQTDFDFVRQLIEQDLIPDDVTIQVLVQCREHLIDRTFESIRGAKRAIVHFYNSTSTLQRRVVFGLDKDGITDIATTGARLCQKYAEIHTPDTEIFYEYSPESYTGTELDYALEICSAVIDVIDPTPDRPLIINLPATVEMATPNVYADSIEWMHRNLPRRDSVILSLHPHNDRGTAVAAAELGLLAGADRIEGCLFGNGERTGNVDLVTLGLNLFSQGVDPQVDFSTIDEIKRTVEYCNQLPVHERHPYAGDLVYTAFSGSHQDAIKKGFAALQDDADAAGTPIDDFTWGVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKEEHKLDLPRRLQIEFSGVVQHHTDAEGGEVGPQQMWDIFAGEYLVEHQMATAFTVENYSTATVDGKVEIDVEVFHRGARRPLAGVGNGPIAAFVQAVEPLGISARVLDYQEHALTSGGDAQAAAYVEVQVGDASYWGVGIDSNIVSASIKAVTSAINRAR
>NC_017093.1|WP_041831682.1|8471263_8471992_+|hypothetical-protein
MLALAPTAGCSGDTPEQAPSSPAPSAVAGPAADASDALAGLAALALDRRYAALYTWDVGDGQPRNVIAMVANDGSWRVDIPRGAQGGTTDVSIVRTAAGVHQCSLGVTSTCVLVADKGEKVPGRYDPRVQRLFRQWLPAFTDRHEALAVSAVRPLAGAQGSCFSVDSVAAGLDAPVDVGIYCYAPDGLLTAARVNFGVLKLVKQVAAPATVQLPGPVISGTPLGMDAPPPPVVQPSSAGLPG
>NC_017093.1|WP_014447941.1|8469823_8471089_-|aspartate-kinase
MALVVQKYGGSSVATAERIKRVAERIVAARKAGDDVVVVVSAMGDTTDELVDLANQVSPLPPGREMDMLLTAGERISMALLAMAIHNLGYEARSYTGSQAGVLTTSTHGKARIIDVTPGRLRTALDEGAIAIVAGFQGVSQDTKDITTLGRGGSDTTAVALAAALHADVCEIYTDVDGVFTADPRIVPNAKHIKQITYEEMLELAAGGAKVLMLRCVEYARRFKVPIHVRSSYSNKEGTLVTGSMEDPDVEQALITGVAHERSEAKITIVGVPDEPGSAGRIFETVAQAEINIDMIVQNISTEGTGRTDISFTLPKADGPTAMTALDKIKDQIKFKSLLFDDHVGKVSLIGAGMRSHPGVAAAFFACIGAAGVNIEMISTSEIRVSVVCRDTDLDTAVRAVHDQFDLGGNEEAVVYAGTGR
>NC_017093.1|WP_014447940.1|8468750_8469815_-|aspartate-semialdehyde-dehydrogenase
MAQPTLAVVGATGSVGSVMLELLSSRRNVWGEIRLIASARSSGKVLTCRGEELEVRELTAEAFDGVDVAMFDVPDDVSVQWAPIATARGAVVVDNSSAFRMEPDVPLVVPEVNREVLRHRPRGIVASANCTTAAMIMAVAPLHYEFGLRELVLASYQSASGAGQDGVDTLHDQLTKVAGDRLLGSRPGNVRQAVGDDLGPFPAPLALNVVPWSGEPAGLGWSSEELKLRNESRKILGMPALKVSATCVRVPVVTGHSIAVHAVFAAEVTADAARQVLRNAPGVIVVDDPEAGEFPMPIDAVGTDPSWVGRIRRAMDDPRALSFFVTGDNRRKGAALNTVQIAELLAAEIGKKDS
>NC_017093.1|WP_014447939.1|8468433_8468754_-|divalent-cation-tolerance-protein-CutA
MTTDICEVVITAADPEWLAGFTRRLVADRLAACGQQIAAIRSIYRWDGAVQDDPEARVALHTRVDLVERIIERAGAEHPYDVPCVLALPILAANPAYADWVRQETS
>NC_017093.1|WP_014447937.1|8467383_8467908_+|orotate-phosphoribosyltransferase
MTDSDLARQVRTVSRLTGEFTLRSGRTATEYFDKYQFEADPVLLDKLAEQLAVLIPEGTEVLAGLEMGGIAVVTALARHAKLPTAFVRKQAKQYGTARLAEGAEVAGRRVLIVEDVVTSGGQVVLSTNDLRRLGAHVDHAVCVIDRQEGGAAALATEGITLRALLTRADLDAVA
>NC_017093.1|WP_014447936.1|8466969_8467245_-|hypothetical-protein
MTPFAMLFLLALAGSSCFALGRALGRGERYERGYREGFRDGETGSLARATRLMQLGDRPSVAPAVEQMIGPYAVPQQVAPRTVAPRPQLAV
>NC_017093.1|WP_014447948.1|8479349_8480387_-|dipeptide-ABC-transporter-ATP-binding-protein
MSENLLEATGVQKHFPITKGLFKRQIGAVRAVDGIDLNVRAGETLGLVGESGCGKSTLGRLFTRILEPTDGKIVFEGEDITHKSVTQMRPLRRDVQMIFQDPYSSLNPRHTVGSIISAPLQIQNIPTPNGLKTAVQELLELVGLNPEHYNRYPHEFSGGQRQRIGIARALALKPKLIVADEPVSALDVSIQAQVVNLLEDLQNEFDLTYVFIAHDLSVVRHISDRVAVMYLGKVVEIAERDELYKNPRHPYTVALMSAVPVPDPVRRDRAQRERVLLTGDVPSPINPPSGCRFRTRCWKAQDICATEEPPLVTRLDDPESHLTACHFPVVSDETVAGRRSAATPA
>NC_017093.1|WP_014447949.1|8480405_8481446_-|ABC-transporter-ATP-binding-protein
MSASSATDRPFLEVKDLTVRFETDDGIVQAVSGSTFSLKAGQTLGIVGESGSGKSVTSLAVLGLHRTRSNAKVTGEIWLDDKELVTATDEEVRGLRGGKMAMIFQDPLSAMHPYFTVGSQIVEAYRVHHPGVNKKAARERAIDMLARVGIPQPERRFHDYAHQFSGGMRQRAMIAMALVNDPKLLIADEPTTALDVTVQAQILDLIRDLQEEFGSAVIMITHDLGVVAELADEVLVMYGGKVIERGPAVDLFQRPQHPYTWGLLGSMPRLDREVRDRLNPVKGSPPSLINLPDGCAFHPRCPYAGRNGDRSFKEVPILSGGTHGVACHLPPDLRTKIFQEEVLPNL
>NC_017093.1|WP_014447950.1|8481457_8482459_-|ABC-transporter-permease
MLAYIIRRLINAVITLLVVTLVTFGIFFGVPKITGNDPALLYIGKTADAASIEGIRTKMGLADPILVQYGKFLKGLVVGRDYANGPDVTHCPAPCLGYSFKTDQEVTPLLLDELPVTLSLAIGAAILWLIMGISTGVISALRRGSLLDRAVMTGALAGVSLPIYFTGLLASAVFIYWLEWLPPSNYVPFLESPADWFVSLLLPWITLAFLFSATYARLTRANMLETLGEDYIRTARAKGLRERTVIGKHGLRSGLTPIVTVFGLDLGALLGGAVLTEAVFNLRGLGYQALTAIRANDLPVILGVTMIAAFFIVFANLIVDLVYGVIDPRVRLS
>NC_017093.1|WP_041830338.1|8482577_8484362_-|ABC-transporter-substrate-binding-protein
MSRKTRAAAAAGVAVVLGLTTAACGGGSDSDDKGSSSSGGKAAYNAAITDVVNPSTTKGGTLNLWTSQDADSWDPARGYYAFVWNLNRLYTRKLVEYSAVPGKAGLELQPDLAEALPTISDDKLTYTFKLRSGLKWDDGAPITSKDVKYGIERVWASDAINGGPVYLPGLLDQGQNYPGPYKDTDPNKLGLKSVTTPDDSTITFKLQKPSSDFIYLLAMPGSGPVPQKRDTGAQYGSAPAASGPYMFKEGGIQPGKSVSWVRNPNWDQATDPIRKALPDAINLTITTNAEDLDARLLAGTADLDVGQTGVQASARTKVLTDPNMKANADTPTTGFLRYAGLATSVAPLDNIECRKAVIYAADPTTLQTARGGPIAGGDIGTSMLPPNIAGSDAKYDPFNRLQGKAQVDEAKKALAACGKPNGFDTIIAVRNNREAEVKTSEALQAALKVVGINAKIEQYDGAQQPSITGAPDNVKRKGYGIIIGGWGADYPTGSGYMQPLADSRFIPDNGNYNLAEIKDPAIDKLFDDAAGETDATKAAEIYSQINHKIMEGAYYLPFVVDKALNYRNPRLTNVYIHDAFGMVDFQAVGVSDGK
>NC_017093.1|WP_014447952.1|8484436_8485444_-|ABC-transporter-permease
MSLGPEASIVDETTPPTADAAEVRGPGEKAIAGRSLKQIAWRRLKKDKVAIGGACVVLFLILIAILAPLLTRLFGYPIDEWHGDEIDKTLGTPIHPWGGITKDFLLGVEPTTGRDIFSRIVYGAQTSLTVAFLSAFLSTILGVLFGTAAGFLGGWVDSVISRVMDFLLAFPQLLFSIALVSVLPQEFLGLGTRWSRVSVLIMVIGFFGWPYIGRIVRGQTLSLREREFVEAARAMGARSPRILFRELLPNLAAPILVYTTLIIPTNILTEAALSFLGVGIPPPWPSWGGMLSDAVNFYQIDPMFMIIPGGMIFITVLAFNLFGDGLRDALDPKAR
>NC_017093.1|WP_014447953.1|8485848_8486442_-|recombination-protein-RecR
MYEGAIQDLIDELGRLPGVGPKSAQRIAFHILSADPADVNRLAGALRKVKELVRFCTTCFNVAESDQCRVCRDTRRTNEVLCVVEEPKDVVAIERTGEFRGRYHVLGGAINPLEGVGPDNLKIRELLIRLGTGEVKELILATDPNTEGEATATYLGLLVKPMGIAVTRLASGLPVGGDLEYADEITLGRAFEGRRAI
>NC_017093.1|WP_014447954.1|8486445_8486769_-|YbaB/EbfC-family-nucleoid-associated-protein
MRPGGQPNMQQIMKQAQKMQQQVAQAQAELAEAELTGTAGGGLVTVTITGLGEFKAVKIDPKAVDADDVETLEDLLLAAIHNAAEAQRELAESKMGPATGGFSLPGF
>NC_017093.1|WP_014447955.1|8486911_8490052_-|DNA-polymerase-III-subunit-gamma-and-tau
MALALYRKYRPRTFAEVIGQEHVTEPLSQALRSGRLNHAYLFSGPRGCGKTSSARILARSLNCEQGPTPDPCGVCASCKSLANDGGGSIDVIEIDAASHGGVDDAREIREKAFFAPASSRYKIYVIDEAHMVSSAGFNALLKLVEEPPDFVKFIFATTEPDKVLGTIRSRTHHYPFRLIPPATLRPYLQQLCEAEGVTVDPAVFPLVVRAGGGSARDTLSILDQLIAGSGPDGVSYSRAVALLGVTDVALIDEMCEAIAAADGAAAYATIDRVAEAGHDPRRFASDLLERFRDLIVLQQVPDAVSKGLIDGPADQLEAMAGQVTKLGPATLSRSADIVHNGLVEMRGTTAPRLLLELITARMLLPGADDSSTALLQRLERLERGSSPLGVRGEPTPADSGDETSRASSTVQGAGGVGDVGSGGDAGLGGGGALGGGKAAAKAAAAAAAAAAAKGRPAGAASRAAAPVSPAPVAAAPVSAAPVSAVPVSPAPVSAAPVSAAPVSVAPVSAAPGAPDWNAVADGGYDEEPPPWDDEPAEPAPAAPPVDRLEDVRAAWLELGRSHEKVGVMQKSGIDLRAVEGDTVVFGAPNPKYAERLVTGYQGVITEAFGRALGGQWQIRCEVGEASPARAATPGSRDQSPNRRPSSATPGRPAQPAAVASSTAPERNTGRTESRPSRPQRPSSPDSDDEWPAPARPAPDTAAPARPAPAAATPARPAQATAASEQVSDEGDTDWPEPVRPGSAAPRAAEPIAADDDWPEPVKPGAAGRPPASPPQAAEPVAAAPAPVTTPAHPDASGSAHAPANAYTSGSAHASANPDASSGAHAPANADASGSAHAPANLSTPPAVNPPAPVSPSAAGGAPAAPSAPVPGHQPARVNPAAPASPPSAAKAVPARSAAMEAARAAAANARNAAAARPQGSPAAGAPGGAGAPGGGPAAPRAASAGGGAVGGGLAAARAASAAAAGPAAGRAGGGAAWSDGTPTEEAPYDPEFDGLPAAGAAAIEGFDPGDEPLDDVLDEKTARQSGEELAMQLLRDAFGAEKIGEL
>NC_017093.1|WP_157435209.1|8490794_8491658_+|hypothetical-protein
MCPVSDKRHVQTRIDILRQILLLSYRSWRLEQIHWGDALKRTRKAVTNVLIAALTASAIAIFADASAAHAGPDDPGTGGPGSGGQPTAPPSAVVPEVIGNDSDGNPVYSTGGNGIVDPAEDSDSLSDEPFAEVPETEGKPDATTQGTGETCPAKTTGTVRNIPNSLKVDWADSVINRTSGKVSYTVKAETSKKFTWSVGASVSGEGKLWIFAKVSATINGNIAHEKSTIYGSSITVEVPAHKTMKADRGMWQEKFSYKYKTTTKNCSWKSGSGTGWAPYRQAWHVYS
>NC_017093.1|WP_014447957.1|8491993_8492293_+|hypothetical-protein
MSGSGSAQTPPFQVDEKLFTVRIACIGGGELQLFQGEEKVEVSCDGSTRRVHVNTDAKEERVPITASAKQEWTVSIVVTKDFSTAGATPTADPSASALG

Crispr_ID: NC_017093_25

• CRISPR_ID: NC_017093_25
• CRISPR_location: 8477847-8478140
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of NC_017093_25

Consensus_repeat	Method
AGCGGCAACGACCGGATCGTCGG	CRISPRCasFinder

spacers of NC_017093_25

>25.1|8477870|31|NC_017093|CRISPRCasFinder
CGGCAGCGGCAACGACCGGATCGTCGGTGAG
>25.2|8477924|31|NC_017093|CRISPRCasFinder
CGCGGCCGGCAACGACAGCCTCGACGGAGGT
>25.3|8477978|31|NC_017093|CRISPRCasFinder
AAACCAGGGCCATGACAAGGTGTGGGGCGGC
>25.4|8478032|31|NC_017093|CRISPRCasFinder
CCACGACGGCGACGACACCCTCTACGGTGAC
>25.5|8478086|31|NC_017093|CRISPRCasFinder
CAGCTGGGGCACTGACAAGGTCTGGGGTGGC

CRISPR arrays and Neighbor proteins around NC_017093_25

CRISPR arrays

The CRISPR arrays of NC_017093_25

>merge|NC_017093|25|8477847-8478140|CRISPRCasFinder
AGCGGCAACGACCGGTTGACCGGCGGCAGCGGCAACGACCGGATCGTCGGTGAGTCCGGCAACGACCGGGTGTACGGCGCGGCCGGCAACGACAGCCTCGACGGAGGTACCGGCAACGACCGGATCGTCGGAAACCAGGGCCATGACAAGGTGTGGGGCGGCGCCGGCGACGACAGCATCCTCGGCCACGACGGCGACGACACCCTCTACGGTGACGCCGGCAACGACGTCATCGAGGGCAGCTGGGGCACTGACAAGGTCTGGGGTGGCAGCGGCAACGACCGGCTCGGTGGC

>NC_017093|25|24|8477847-8478140|CRISPRCasFinder
AGCGGCAACGACCGGTTGACCGG	CGGCAGCGGCAACGACCGGATCGTCGGTGAG
TCCGGCAACGACCGGGTGTACGG	CGCGGCCGGCAACGACAGCCTCGACGGAGGT
ACCGGCAACGACCGGATCGTCGG	AAACCAGGGCCATGACAAGGTGTGGGGCGGC
GCCGGCGACGACAGCATCCTCGG	CCACGACGGCGACGACACCCTCTACGGTGAC
GCCGGCAACGACGTCATCGAGGG	CAGCTGGGGCACTGACAAGGTCTGGGGTGGC
AGCGGCAACGACCGGCTCGGTGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_157435209.1|8490794_8491658_+|hypothetical-protein	unknown	unknown	gnl|CDD|380807
NC_017093.1|WP_014447953.1|8485848_8486442_-|recombination-protein-RecR	unknown	unknown	gnl|CDD|234616
NC_017093.1|WP_014447946.1|8474996_8477303_+|calcium-binding-protein	unknown	unknown	gnl|CDD|380205
NC_017093.1|WP_041830338.1|8482577_8484362_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173871
NC_017093.1|WP_014447948.1|8479349_8480387_-|dipeptide-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|236898
NC_017093.1|WP_014447937.1|8467383_8467908_+|orotate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234771
NC_017093.1|WP_014447943.1|8472177_8473902_+|2-isopropylmalate-synthase	unknown	unknown	gnl|CDD|235154
NC_017093.1|WP_014447957.1|8491993_8492293_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014447940.1|8468750_8469815_-|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|237845
NC_017093.1|WP_157435554.1|8474119_8474590_+|DUF1524-domain-containing-protein	unknown	unknown	gnl|CDD|377857
NC_017093.1|WP_014447936.1|8466969_8467245_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014447941.1|8469823_8471089_-|aspartate-kinase	unknown	unknown	gnl|CDD|235843
NC_017093.1|WP_014447955.1|8486911_8490052_-|DNA-polymerase-III-subunit-gamma-and-tau	unknown	unknown	gnl|CDD|236090
NC_017093.1|WP_014447939.1|8468433_8468754_-|divalent-cation-tolerance-protein-CutA	unknown	unknown	gnl|CDD|376987
NC_017093.1|WP_014447952.1|8484436_8485444_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NC_017093.1|WP_014447949.1|8480405_8481446_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|223521
NC_017093.1|WP_157435556.1|8474484_8474850_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_041831682.1|8471263_8471992_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014447954.1|8486445_8486769_-|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl|CDD|234669
NC_017093.1|WP_014447950.1|8481457_8482459_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_157435209.1|8490794_8491658_+|hypothetical-protein	gnl|CDD|380807	cd20237, PFM_LIN24-like, pore-forming module of Caenorhabditis elegans LIN-24 and similar aerolysin-type beta-barrel pore-forming proteins. The process of cytotoxic cell death occurs in Caenorhabditis elegans containing mutations in either of lin-24 and lin-33. The cytotoxicity caused by mutation of either gene requires the function of the other. Genes required for the engulfment of apoptotic corpses function in the cytotoxic cell deaths induced by mutations in lin-24 and lin-33. It has been proposed that Caenorhabditis elegans LIN-24 may function to interact with bacterial toxins having similarity with it, and inactivate these, thereby allowing C. elegans to consume or survive exposure to bacteria that produce such toxins. Members of this group belong to the aerolysin family of beta-pore-forming proteins (beta-PFPs). PFPs are generally secreted as water-soluble monomers, which upon binding to target lipid membranes, oligomerize and form transmembrane pores harmful to cells. Beta-PFPs form pores by transmembrane beta-barrels. Aerolysin-type beta-PFPs are believed to use an amphipathic beta-hairpin to form the beta-barrel, are found in all kingdoms of life and many are bacterial toxins. In addition to having a role in microbial infection, they have potential as biotechnological sensors and delivery systems. They share a similar monomeric architecture, with a variable membrane-binding domain and a structurally conserved pore-forming region. A significant portion of the monomeric subunit structure is re-organized to form the pore. Oligomers formed by members of the aerolysin family include: hepta- (aerolysin), octa- (Dln1), and nonameric oligomers (lysenin and monalysin).	0.00744822
NC_017093.1|WP_014447953.1|8485848_8486442_-|recombination-protein-RecR	gnl|CDD|234616	PRK00076, recR, recombination protein RecR; Reviewed.	3.28459e-114
NC_017093.1|WP_014447946.1|8474996_8477303_+|calcium-binding-protein	gnl|CDD|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	1.6739e-16
NC_017093.1|WP_041830338.1|8482577_8484362_-|ABC-transporter-substrate-binding-protein	gnl|CDD|173871	cd08506, PBP2_clavulanate_OppA2, The substrate-binding domain of an oligopeptide binding protein (OppA2) from the biosynthesis pathway of the beta-lactamase inhibitor clavulanic acid contains the type 2 periplasmic binding fold. Clavulanic acid (CA), a clinically important beta-lactamase inhibitor, is one of a family of clavams produced as secondary metabolites by fermentation of Streptomyces clavuligeru. The biosynthesis of CA proceeds via multiple steps from the precursors, glyceraldehyde-3-phosphate and arginine. CA possesses a characteristic (3R,5R) stereochemistry essential for reaction with penicillin-binding proteins and beta-lactamases. Two genes (oppA1 and oppA2) in the clavulanic acid gene cluster encode oligopeptide-binding proteins that are required for CA biosynthesis. OppA1/2 is involved in the binding and transport of peptides across the cell membrane of Streptomyces clavuligerus. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	2.46662e-160
NC_017093.1|WP_014447937.1|8467383_8467908_+|orotate-phosphoribosyltransferase	gnl|CDD|234771	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated.	9.86158e-43
NC_017093.1|WP_014447943.1|8472177_8473902_+|2-isopropylmalate-synthase	gnl|CDD|235154	PRK03739, PRK03739, 2-isopropylmalate synthase; Validated.	0
NC_017093.1|WP_014447940.1|8468750_8469815_-|aspartate-semialdehyde-dehydrogenase	gnl|CDD|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	3.79724e-155
NC_017093.1|WP_157435554.1|8474119_8474590_+|DUF1524-domain-containing-protein	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	1.3374e-11
NC_017093.1|WP_014447948.1|8479349_8480387_-|dipeptide-ABC-transporter-ATP-binding-protein	gnl|CDD|236898	PRK11308, dppF, dipeptide transporter ATP-binding subunit; Provisional.	1.00317e-154
NC_017093.1|WP_014447941.1|8469823_8471089_-|aspartate-kinase	gnl|CDD|235843	PRK06635, PRK06635, aspartate kinase; Reviewed.	0
NC_017093.1|WP_014447955.1|8486911_8490052_-|DNA-polymerase-III-subunit-gamma-and-tau	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0
NC_017093.1|WP_014447939.1|8468433_8468754_-|divalent-cation-tolerance-protein-CutA	gnl|CDD|376987	pfam03091, CutA1, CutA1 divalent ion tolerance protein. Several gene loci with a possible involvement in cellular tolerance to copper have been identified. One such locus in eubacteria and archaebacteria, cutA, is thought to be involved in cellular tolerance to a wide variety of divalent cations other than copper. The cutA locus consists of two operons, of one and two genes. The CutA1 protein is a cytoplasmic protein, encoded by the single-gene operon and has been linked to divalent cation tolerance. It has no recognized structural motifs. This family also contains putative proteins from eukaryotes (human and Drosophila).	1.26893e-38
NC_017093.1|WP_014447949.1|8480405_8481446_-|ABC-transporter-ATP-binding-protein	gnl|CDD|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.47363e-174
NC_017093.1|WP_014447952.1|8484436_8485444_-|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.05333e-91
NC_017093.1|WP_014447954.1|8486445_8486769_-|YbaB/EbfC-family-nucleoid-associated-protein	gnl|CDD|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	2.4109e-39
NC_017093.1|WP_014447950.1|8481457_8482459_-|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	9.66918e-103

Protein sequences

>NC_017093.1|WP_014447946.1|8474996_8477303_+|calcium-binding-protein
MSRSQWLTRIGVALFTTIAVGAVGTPAFAASTGTASVSGKSTVVFKAGSGRTNSVKITRSLRTITIDDKVAVKAGKGCKPVKGDKTKVRCTPYMTPTLVRAYLGDRNDVLVSTAGTPLKAYGGSGDDKITGSSGADRLVGDSGNDQIWGAAGNDSLDGGTGNDRVKGGTGNDKLYGSAGNDTVNGESGNDSLDGGSGNDSIAGSTGNDNELGGTGNDTFVQGGNGRADRDVIRGQAGRDTVSYATRTGTVWISTDTTKADDGEAGERDTVHPDIEVLVGGRGADFLRGGGNATAFYGGDGNDHLVASAHHSLLDGGNGRDRVFGGQGNDTLRGGNDNDELIGWSGNDLLDGGNGDDYLAGDDPDLESSSARGNDVLRGGPGSDRVDYNGNSKPVTVDLDGATGDDGQAGEHDTVGSDVERLIGSPQSDVLTGNSAANHIVGGFGDDVIRGGGGNDTLSGEDGADRVFGETGDDTLQGGNGNDVLTGDSGNDKEYGDAGDDTFRQPQASGADADTFAGGTGTDFVDYSYRTTSSVTLSLNGVKGDDGGDSEGDTLPADVEVLAGSALGGDTIRGSSGNDTLHGCGFGDKIYGEGGDDVIHGEGVCSATAERDSIEPQGSYLVGGAGDDKITGTKYSDRFFGDYDTPSDTPRPAGVDTLIGTSGSNGSDYDDDAADYRYASGPVITGNVPTGKTGERDKLSGISIVFGSEFDDVLALDADYHWVYDPTLYGLGGDDELYGGTATWLNGGDGTDLCRLSETSTGEKRNCEL
>NC_017093.1|WP_157435556.1|8474484_8474850_+|hypothetical-protein
MVHVRQGLGNREDLLEADRHREGEGGARRHAGDLLMASPEKSLTTDIVPGPGGVMTDEVGVVTGDLTLRTEISGGDVVLRVQYKDAEEWYAVTGGKAPLADPADLEAVHSIAVGLLNRPGG
>NC_017093.1|WP_157435554.1|8474119_8474590_+|DUF1524-domain-containing-protein
MKGYTREKFPHWRDTGSNCDVRDSVLERDGEKVKRSGCNVVAGTWRSLYDGEVLNSPTKVDIDHMVPLANAWRSGAAKWDNDKRGDFANDLERPQLIAVSASSNRSKGDQDPSTWKPSDRDSWCTYAKDWVTVKTYWKLTVTEKEKVALDDMLETC
>NC_017093.1|WP_014447943.1|8472177_8473902_+|2-isopropylmalate-synthase
MSDAFKTQAPSAMPFQRYEAYQKQFDVPLTDRQWPSRVVETAPRWCAVDLRDGNQALIDPMSPERKRRMFMLLVKMGYKEIEVGFPAASQTDFDFVRQLIEQDLIPDDVTIQVLVQCREHLIDRTFESIRGAKRAIVHFYNSTSTLQRRVVFGLDKDGITDIATTGARLCQKYAEIHTPDTEIFYEYSPESYTGTELDYALEICSAVIDVIDPTPDRPLIINLPATVEMATPNVYADSIEWMHRNLPRRDSVILSLHPHNDRGTAVAAAELGLLAGADRIEGCLFGNGERTGNVDLVTLGLNLFSQGVDPQVDFSTIDEIKRTVEYCNQLPVHERHPYAGDLVYTAFSGSHQDAIKKGFAALQDDADAAGTPIDDFTWGVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKEEHKLDLPRRLQIEFSGVVQHHTDAEGGEVGPQQMWDIFAGEYLVEHQMATAFTVENYSTATVDGKVEIDVEVFHRGARRPLAGVGNGPIAAFVQAVEPLGISARVLDYQEHALTSGGDAQAAAYVEVQVGDASYWGVGIDSNIVSASIKAVTSAINRAR
>NC_017093.1|WP_041831682.1|8471263_8471992_+|hypothetical-protein
MLALAPTAGCSGDTPEQAPSSPAPSAVAGPAADASDALAGLAALALDRRYAALYTWDVGDGQPRNVIAMVANDGSWRVDIPRGAQGGTTDVSIVRTAAGVHQCSLGVTSTCVLVADKGEKVPGRYDPRVQRLFRQWLPAFTDRHEALAVSAVRPLAGAQGSCFSVDSVAAGLDAPVDVGIYCYAPDGLLTAARVNFGVLKLVKQVAAPATVQLPGPVISGTPLGMDAPPPPVVQPSSAGLPG
>NC_017093.1|WP_014447941.1|8469823_8471089_-|aspartate-kinase
MALVVQKYGGSSVATAERIKRVAERIVAARKAGDDVVVVVSAMGDTTDELVDLANQVSPLPPGREMDMLLTAGERISMALLAMAIHNLGYEARSYTGSQAGVLTTSTHGKARIIDVTPGRLRTALDEGAIAIVAGFQGVSQDTKDITTLGRGGSDTTAVALAAALHADVCEIYTDVDGVFTADPRIVPNAKHIKQITYEEMLELAAGGAKVLMLRCVEYARRFKVPIHVRSSYSNKEGTLVTGSMEDPDVEQALITGVAHERSEAKITIVGVPDEPGSAGRIFETVAQAEINIDMIVQNISTEGTGRTDISFTLPKADGPTAMTALDKIKDQIKFKSLLFDDHVGKVSLIGAGMRSHPGVAAAFFACIGAAGVNIEMISTSEIRVSVVCRDTDLDTAVRAVHDQFDLGGNEEAVVYAGTGR
>NC_017093.1|WP_014447940.1|8468750_8469815_-|aspartate-semialdehyde-dehydrogenase
MAQPTLAVVGATGSVGSVMLELLSSRRNVWGEIRLIASARSSGKVLTCRGEELEVRELTAEAFDGVDVAMFDVPDDVSVQWAPIATARGAVVVDNSSAFRMEPDVPLVVPEVNREVLRHRPRGIVASANCTTAAMIMAVAPLHYEFGLRELVLASYQSASGAGQDGVDTLHDQLTKVAGDRLLGSRPGNVRQAVGDDLGPFPAPLALNVVPWSGEPAGLGWSSEELKLRNESRKILGMPALKVSATCVRVPVVTGHSIAVHAVFAAEVTADAARQVLRNAPGVIVVDDPEAGEFPMPIDAVGTDPSWVGRIRRAMDDPRALSFFVTGDNRRKGAALNTVQIAELLAAEIGKKDS
>NC_017093.1|WP_014447939.1|8468433_8468754_-|divalent-cation-tolerance-protein-CutA
MTTDICEVVITAADPEWLAGFTRRLVADRLAACGQQIAAIRSIYRWDGAVQDDPEARVALHTRVDLVERIIERAGAEHPYDVPCVLALPILAANPAYADWVRQETS
>NC_017093.1|WP_014447937.1|8467383_8467908_+|orotate-phosphoribosyltransferase
MTDSDLARQVRTVSRLTGEFTLRSGRTATEYFDKYQFEADPVLLDKLAEQLAVLIPEGTEVLAGLEMGGIAVVTALARHAKLPTAFVRKQAKQYGTARLAEGAEVAGRRVLIVEDVVTSGGQVVLSTNDLRRLGAHVDHAVCVIDRQEGGAAALATEGITLRALLTRADLDAVA
>NC_017093.1|WP_014447936.1|8466969_8467245_-|hypothetical-protein
MTPFAMLFLLALAGSSCFALGRALGRGERYERGYREGFRDGETGSLARATRLMQLGDRPSVAPAVEQMIGPYAVPQQVAPRTVAPRPQLAV
>NC_017093.1|WP_014447948.1|8479349_8480387_-|dipeptide-ABC-transporter-ATP-binding-protein
MSENLLEATGVQKHFPITKGLFKRQIGAVRAVDGIDLNVRAGETLGLVGESGCGKSTLGRLFTRILEPTDGKIVFEGEDITHKSVTQMRPLRRDVQMIFQDPYSSLNPRHTVGSIISAPLQIQNIPTPNGLKTAVQELLELVGLNPEHYNRYPHEFSGGQRQRIGIARALALKPKLIVADEPVSALDVSIQAQVVNLLEDLQNEFDLTYVFIAHDLSVVRHISDRVAVMYLGKVVEIAERDELYKNPRHPYTVALMSAVPVPDPVRRDRAQRERVLLTGDVPSPINPPSGCRFRTRCWKAQDICATEEPPLVTRLDDPESHLTACHFPVVSDETVAGRRSAATPA
>NC_017093.1|WP_014447949.1|8480405_8481446_-|ABC-transporter-ATP-binding-protein
MSASSATDRPFLEVKDLTVRFETDDGIVQAVSGSTFSLKAGQTLGIVGESGSGKSVTSLAVLGLHRTRSNAKVTGEIWLDDKELVTATDEEVRGLRGGKMAMIFQDPLSAMHPYFTVGSQIVEAYRVHHPGVNKKAARERAIDMLARVGIPQPERRFHDYAHQFSGGMRQRAMIAMALVNDPKLLIADEPTTALDVTVQAQILDLIRDLQEEFGSAVIMITHDLGVVAELADEVLVMYGGKVIERGPAVDLFQRPQHPYTWGLLGSMPRLDREVRDRLNPVKGSPPSLINLPDGCAFHPRCPYAGRNGDRSFKEVPILSGGTHGVACHLPPDLRTKIFQEEVLPNL
>NC_017093.1|WP_014447950.1|8481457_8482459_-|ABC-transporter-permease
MLAYIIRRLINAVITLLVVTLVTFGIFFGVPKITGNDPALLYIGKTADAASIEGIRTKMGLADPILVQYGKFLKGLVVGRDYANGPDVTHCPAPCLGYSFKTDQEVTPLLLDELPVTLSLAIGAAILWLIMGISTGVISALRRGSLLDRAVMTGALAGVSLPIYFTGLLASAVFIYWLEWLPPSNYVPFLESPADWFVSLLLPWITLAFLFSATYARLTRANMLETLGEDYIRTARAKGLRERTVIGKHGLRSGLTPIVTVFGLDLGALLGGAVLTEAVFNLRGLGYQALTAIRANDLPVILGVTMIAAFFIVFANLIVDLVYGVIDPRVRLS
>NC_017093.1|WP_041830338.1|8482577_8484362_-|ABC-transporter-substrate-binding-protein
MSRKTRAAAAAGVAVVLGLTTAACGGGSDSDDKGSSSSGGKAAYNAAITDVVNPSTTKGGTLNLWTSQDADSWDPARGYYAFVWNLNRLYTRKLVEYSAVPGKAGLELQPDLAEALPTISDDKLTYTFKLRSGLKWDDGAPITSKDVKYGIERVWASDAINGGPVYLPGLLDQGQNYPGPYKDTDPNKLGLKSVTTPDDSTITFKLQKPSSDFIYLLAMPGSGPVPQKRDTGAQYGSAPAASGPYMFKEGGIQPGKSVSWVRNPNWDQATDPIRKALPDAINLTITTNAEDLDARLLAGTADLDVGQTGVQASARTKVLTDPNMKANADTPTTGFLRYAGLATSVAPLDNIECRKAVIYAADPTTLQTARGGPIAGGDIGTSMLPPNIAGSDAKYDPFNRLQGKAQVDEAKKALAACGKPNGFDTIIAVRNNREAEVKTSEALQAALKVVGINAKIEQYDGAQQPSITGAPDNVKRKGYGIIIGGWGADYPTGSGYMQPLADSRFIPDNGNYNLAEIKDPAIDKLFDDAAGETDATKAAEIYSQINHKIMEGAYYLPFVVDKALNYRNPRLTNVYIHDAFGMVDFQAVGVSDGK
>NC_017093.1|WP_014447952.1|8484436_8485444_-|ABC-transporter-permease
MSLGPEASIVDETTPPTADAAEVRGPGEKAIAGRSLKQIAWRRLKKDKVAIGGACVVLFLILIAILAPLLTRLFGYPIDEWHGDEIDKTLGTPIHPWGGITKDFLLGVEPTTGRDIFSRIVYGAQTSLTVAFLSAFLSTILGVLFGTAAGFLGGWVDSVISRVMDFLLAFPQLLFSIALVSVLPQEFLGLGTRWSRVSVLIMVIGFFGWPYIGRIVRGQTLSLREREFVEAARAMGARSPRILFRELLPNLAAPILVYTTLIIPTNILTEAALSFLGVGIPPPWPSWGGMLSDAVNFYQIDPMFMIIPGGMIFITVLAFNLFGDGLRDALDPKAR
>NC_017093.1|WP_014447953.1|8485848_8486442_-|recombination-protein-RecR
MYEGAIQDLIDELGRLPGVGPKSAQRIAFHILSADPADVNRLAGALRKVKELVRFCTTCFNVAESDQCRVCRDTRRTNEVLCVVEEPKDVVAIERTGEFRGRYHVLGGAINPLEGVGPDNLKIRELLIRLGTGEVKELILATDPNTEGEATATYLGLLVKPMGIAVTRLASGLPVGGDLEYADEITLGRAFEGRRAI
>NC_017093.1|WP_014447954.1|8486445_8486769_-|YbaB/EbfC-family-nucleoid-associated-protein
MRPGGQPNMQQIMKQAQKMQQQVAQAQAELAEAELTGTAGGGLVTVTITGLGEFKAVKIDPKAVDADDVETLEDLLLAAIHNAAEAQRELAESKMGPATGGFSLPGF
>NC_017093.1|WP_014447955.1|8486911_8490052_-|DNA-polymerase-III-subunit-gamma-and-tau
MALALYRKYRPRTFAEVIGQEHVTEPLSQALRSGRLNHAYLFSGPRGCGKTSSARILARSLNCEQGPTPDPCGVCASCKSLANDGGGSIDVIEIDAASHGGVDDAREIREKAFFAPASSRYKIYVIDEAHMVSSAGFNALLKLVEEPPDFVKFIFATTEPDKVLGTIRSRTHHYPFRLIPPATLRPYLQQLCEAEGVTVDPAVFPLVVRAGGGSARDTLSILDQLIAGSGPDGVSYSRAVALLGVTDVALIDEMCEAIAAADGAAAYATIDRVAEAGHDPRRFASDLLERFRDLIVLQQVPDAVSKGLIDGPADQLEAMAGQVTKLGPATLSRSADIVHNGLVEMRGTTAPRLLLELITARMLLPGADDSSTALLQRLERLERGSSPLGVRGEPTPADSGDETSRASSTVQGAGGVGDVGSGGDAGLGGGGALGGGKAAAKAAAAAAAAAAAKGRPAGAASRAAAPVSPAPVAAAPVSAAPVSAVPVSPAPVSAAPVSAAPVSVAPVSAAPGAPDWNAVADGGYDEEPPPWDDEPAEPAPAAPPVDRLEDVRAAWLELGRSHEKVGVMQKSGIDLRAVEGDTVVFGAPNPKYAERLVTGYQGVITEAFGRALGGQWQIRCEVGEASPARAATPGSRDQSPNRRPSSATPGRPAQPAAVASSTAPERNTGRTESRPSRPQRPSSPDSDDEWPAPARPAPDTAAPARPAPAAATPARPAQATAASEQVSDEGDTDWPEPVRPGSAAPRAAEPIAADDDWPEPVKPGAAGRPPASPPQAAEPVAAAPAPVTTPAHPDASGSAHAPANAYTSGSAHASANPDASSGAHAPANADASGSAHAPANLSTPPAVNPPAPVSPSAAGGAPAAPSAPVPGHQPARVNPAAPASPPSAAKAVPARSAAMEAARAAAANARNAAAARPQGSPAAGAPGGAGAPGGGPAAPRAASAGGGAVGGGLAAARAASAAAAGPAAGRAGGGAAWSDGTPTEEAPYDPEFDGLPAAGAAAIEGFDPGDEPLDDVLDEKTARQSGEELAMQLLRDAFGAEKIGEL
>NC_017093.1|WP_157435209.1|8490794_8491658_+|hypothetical-protein
MCPVSDKRHVQTRIDILRQILLLSYRSWRLEQIHWGDALKRTRKAVTNVLIAALTASAIAIFADASAAHAGPDDPGTGGPGSGGQPTAPPSAVVPEVIGNDSDGNPVYSTGGNGIVDPAEDSDSLSDEPFAEVPETEGKPDATTQGTGETCPAKTTGTVRNIPNSLKVDWADSVINRTSGKVSYTVKAETSKKFTWSVGASVSGEGKLWIFAKVSATINGNIAHEKSTIYGSSITVEVPAHKTMKADRGMWQEKFSYKYKTTTKNCSWKSGSGTGWAPYRQAWHVYS
>NC_017093.1|WP_014447957.1|8491993_8492293_+|hypothetical-protein
MSGSGSAQTPPFQVDEKLFTVRIACIGGGELQLFQGEEKVEVSCDGSTRRVHVNTDAKEERVPITASAKQEWTVSIVVTKDFSTAGATPTADPSASALG

Crispr_ID: NC_017093_27

• CRISPR_ID: NC_017093_27
• CRISPR_location: 8487530-8487624
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017093_27

Consensus_repeat	Method
CGCGTTCGCCGGAGCATGTGCGC	CRISPRCasFinder

spacers of NC_017093_27

>27.1|8487553|49|NC_017093|CRISPRCasFinder
TGCCCGAGGCATCCGCGTTCGCCGGAGCATGTGCGCCGCTCGAGGCATC

CRISPR arrays and Neighbor proteins around NC_017093_27

CRISPR arrays

The CRISPR arrays of NC_017093_27

>merge|NC_017093|27|8487530-8487624|CRISPRCasFinder
CAGGTTCGCCGGAGCGTGCGCGCTGCCCGAGGCATCCGCGTTCGCCGGAGCATGTGCGCCGCTCGAGGCATCCGGGTTCGCCGAAGCATGTGCGC

>NC_017093|27|26|8487530-8487624|CRISPRCasFinder
CAGGTTCGCCGGAGCGTGCGCGC	TGCCCGAGGCATCCGCGTTCGCCGGAGCATGTGCGCCGCTCGAGGCATC
CGGGTTCGCCGAAGCATGTGCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017093.1|WP_157435209.1|8490794_8491658_+|hypothetical-protein	unknown	unknown	gnl|CDD|380807
NC_017093.1|WP_014447953.1|8485848_8486442_-|recombination-protein-RecR	unknown	unknown	gnl|CDD|234616
NC_017093.1|WP_014447948.1|8479349_8480387_-|dipeptide-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|236898
NC_017093.1|WP_051042645.1|8497230_8497683_-|nucleoside-deaminase	unknown	unknown	gnl|CDD|223663
NC_017093.1|WP_014447964.1|8497709_8498219_-|tRNA-adenosine-deaminase-associated-protein	unknown	unknown	gnl|CDD|274869
NC_017093.1|WP_041830338.1|8482577_8484362_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173871
NC_017093.1|WP_172666650.1|8498308_8498476_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014447946.1|8474996_8477303_+|calcium-binding-protein	unknown	unknown	gnl|CDD|380205
NC_017093.1|WP_014447960.1|8495195_8495537_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NC_017093.1|WP_014447957.1|8491993_8492293_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014447947.1|8477477_8479247_+|calcium-binding-protein	unknown	unknown	gnl|CDD|380205
NC_017093.1|WP_014447954.1|8486445_8486769_-|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl|CDD|234669
NC_017093.1|WP_014447961.1|8495731_8495941_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_157435210.1|8492587_8493910_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014447962.1|8496490_8497204_+|purine-nucleoside-phosphorylase	unknown	unknown	gnl|CDD|180275
NC_017093.1|WP_041830341.1|8493809_8495039_-|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014447949.1|8480405_8481446_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|223521
NC_017093.1|WP_157435556.1|8474484_8474850_+|hypothetical-protein	unknown	unknown	unknown
NC_017093.1|WP_014447952.1|8484436_8485444_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NC_017093.1|WP_014447950.1|8481457_8482459_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017093.1|WP_157435209.1|8490794_8491658_+|hypothetical-protein	gnl|CDD|380807	cd20237, PFM_LIN24-like, pore-forming module of Caenorhabditis elegans LIN-24 and similar aerolysin-type beta-barrel pore-forming proteins. The process of cytotoxic cell death occurs in Caenorhabditis elegans containing mutations in either of lin-24 and lin-33. The cytotoxicity caused by mutation of either gene requires the function of the other. Genes required for the engulfment of apoptotic corpses function in the cytotoxic cell deaths induced by mutations in lin-24 and lin-33. It has been proposed that Caenorhabditis elegans LIN-24 may function to interact with bacterial toxins having similarity with it, and inactivate these, thereby allowing C. elegans to consume or survive exposure to bacteria that produce such toxins. Members of this group belong to the aerolysin family of beta-pore-forming proteins (beta-PFPs). PFPs are generally secreted as water-soluble monomers, which upon binding to target lipid membranes, oligomerize and form transmembrane pores harmful to cells. Beta-PFPs form pores by transmembrane beta-barrels. Aerolysin-type beta-PFPs are believed to use an amphipathic beta-hairpin to form the beta-barrel, are found in all kingdoms of life and many are bacterial toxins. In addition to having a role in microbial infection, they have potential as biotechnological sensors and delivery systems. They share a similar monomeric architecture, with a variable membrane-binding domain and a structurally conserved pore-forming region. A significant portion of the monomeric subunit structure is re-organized to form the pore. Oligomers formed by members of the aerolysin family include: hepta- (aerolysin), octa- (Dln1), and nonameric oligomers (lysenin and monalysin).	0.00744822
NC_017093.1|WP_014447953.1|8485848_8486442_-|recombination-protein-RecR	gnl|CDD|234616	PRK00076, recR, recombination protein RecR; Reviewed.	3.28459e-114
NC_017093.1|WP_014447948.1|8479349_8480387_-|dipeptide-ABC-transporter-ATP-binding-protein	gnl|CDD|236898	PRK11308, dppF, dipeptide transporter ATP-binding subunit; Provisional.	1.00317e-154
NC_017093.1|WP_051042645.1|8497230_8497683_-|nucleoside-deaminase	gnl|CDD|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	2.79013e-60
NC_017093.1|WP_014447964.1|8497709_8498219_-|tRNA-adenosine-deaminase-associated-protein	gnl|CDD|274869	TIGR03941, conserved_hypothetical_protein, putative tRNA adenosine deaminase-associated protein. This model describes a protein family about 200 amino acids in length with only five invariant residues, including an Arg, a Ser-Asp pair, and two Gly residues. Members always are found exclusively in Actinobacteria, and always adjacent to homologs of TadA, a tRNA-specific adenosine deaminase from Escherichia coli. Homology, phyletic pattern, and gene neighborhood together suggest a housekeeping function in tRNA metabolism. [Unknown function, General].	4.22038e-29
NC_017093.1|WP_041830338.1|8482577_8484362_-|ABC-transporter-substrate-binding-protein	gnl|CDD|173871	cd08506, PBP2_clavulanate_OppA2, The substrate-binding domain of an oligopeptide binding protein (OppA2) from the biosynthesis pathway of the beta-lactamase inhibitor clavulanic acid contains the type 2 periplasmic binding fold. Clavulanic acid (CA), a clinically important beta-lactamase inhibitor, is one of a family of clavams produced as secondary metabolites by fermentation of Streptomyces clavuligeru. The biosynthesis of CA proceeds via multiple steps from the precursors, glyceraldehyde-3-phosphate and arginine. CA possesses a characteristic (3R,5R) stereochemistry essential for reaction with penicillin-binding proteins and beta-lactamases. Two genes (oppA1 and oppA2) in the clavulanic acid gene cluster encode oligopeptide-binding proteins that are required for CA biosynthesis. OppA1/2 is involved in the binding and transport of peptides across the cell membrane of Streptomyces clavuligerus. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	2.46662e-160
NC_017093.1|WP_014447946.1|8474996_8477303_+|calcium-binding-protein	gnl|CDD|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	1.6739e-16
NC_017093.1|WP_014447960.1|8495195_8495537_-|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	5.96152e-24
NC_017093.1|WP_014447947.1|8477477_8479247_+|calcium-binding-protein	gnl|CDD|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	1.90284e-22
NC_017093.1|WP_014447954.1|8486445_8486769_-|YbaB/EbfC-family-nucleoid-associated-protein	gnl|CDD|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	2.4109e-39
NC_017093.1|WP_014447962.1|8496490_8497204_+|purine-nucleoside-phosphorylase	gnl|CDD|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	8.78298e-146
NC_017093.1|WP_014447949.1|8480405_8481446_-|ABC-transporter-ATP-binding-protein	gnl|CDD|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.47363e-174
NC_017093.1|WP_014447952.1|8484436_8485444_-|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.05333e-91
NC_017093.1|WP_014447950.1|8481457_8482459_-|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	9.66918e-103

Protein sequences

>NC_017093.1|WP_014447954.1|8486445_8486769_-|YbaB/EbfC-family-nucleoid-associated-protein
MRPGGQPNMQQIMKQAQKMQQQVAQAQAELAEAELTGTAGGGLVTVTITGLGEFKAVKIDPKAVDADDVETLEDLLLAAIHNAAEAQRELAESKMGPATGGFSLPGF
>NC_017093.1|WP_014447953.1|8485848_8486442_-|recombination-protein-RecR
MYEGAIQDLIDELGRLPGVGPKSAQRIAFHILSADPADVNRLAGALRKVKELVRFCTTCFNVAESDQCRVCRDTRRTNEVLCVVEEPKDVVAIERTGEFRGRYHVLGGAINPLEGVGPDNLKIRELLIRLGTGEVKELILATDPNTEGEATATYLGLLVKPMGIAVTRLASGLPVGGDLEYADEITLGRAFEGRRAI
>NC_017093.1|WP_014447952.1|8484436_8485444_-|ABC-transporter-permease
MSLGPEASIVDETTPPTADAAEVRGPGEKAIAGRSLKQIAWRRLKKDKVAIGGACVVLFLILIAILAPLLTRLFGYPIDEWHGDEIDKTLGTPIHPWGGITKDFLLGVEPTTGRDIFSRIVYGAQTSLTVAFLSAFLSTILGVLFGTAAGFLGGWVDSVISRVMDFLLAFPQLLFSIALVSVLPQEFLGLGTRWSRVSVLIMVIGFFGWPYIGRIVRGQTLSLREREFVEAARAMGARSPRILFRELLPNLAAPILVYTTLIIPTNILTEAALSFLGVGIPPPWPSWGGMLSDAVNFYQIDPMFMIIPGGMIFITVLAFNLFGDGLRDALDPKAR
>NC_017093.1|WP_041830338.1|8482577_8484362_-|ABC-transporter-substrate-binding-protein
MSRKTRAAAAAGVAVVLGLTTAACGGGSDSDDKGSSSSGGKAAYNAAITDVVNPSTTKGGTLNLWTSQDADSWDPARGYYAFVWNLNRLYTRKLVEYSAVPGKAGLELQPDLAEALPTISDDKLTYTFKLRSGLKWDDGAPITSKDVKYGIERVWASDAINGGPVYLPGLLDQGQNYPGPYKDTDPNKLGLKSVTTPDDSTITFKLQKPSSDFIYLLAMPGSGPVPQKRDTGAQYGSAPAASGPYMFKEGGIQPGKSVSWVRNPNWDQATDPIRKALPDAINLTITTNAEDLDARLLAGTADLDVGQTGVQASARTKVLTDPNMKANADTPTTGFLRYAGLATSVAPLDNIECRKAVIYAADPTTLQTARGGPIAGGDIGTSMLPPNIAGSDAKYDPFNRLQGKAQVDEAKKALAACGKPNGFDTIIAVRNNREAEVKTSEALQAALKVVGINAKIEQYDGAQQPSITGAPDNVKRKGYGIIIGGWGADYPTGSGYMQPLADSRFIPDNGNYNLAEIKDPAIDKLFDDAAGETDATKAAEIYSQINHKIMEGAYYLPFVVDKALNYRNPRLTNVYIHDAFGMVDFQAVGVSDGK
>NC_017093.1|WP_014447950.1|8481457_8482459_-|ABC-transporter-permease
MLAYIIRRLINAVITLLVVTLVTFGIFFGVPKITGNDPALLYIGKTADAASIEGIRTKMGLADPILVQYGKFLKGLVVGRDYANGPDVTHCPAPCLGYSFKTDQEVTPLLLDELPVTLSLAIGAAILWLIMGISTGVISALRRGSLLDRAVMTGALAGVSLPIYFTGLLASAVFIYWLEWLPPSNYVPFLESPADWFVSLLLPWITLAFLFSATYARLTRANMLETLGEDYIRTARAKGLRERTVIGKHGLRSGLTPIVTVFGLDLGALLGGAVLTEAVFNLRGLGYQALTAIRANDLPVILGVTMIAAFFIVFANLIVDLVYGVIDPRVRLS
>NC_017093.1|WP_014447949.1|8480405_8481446_-|ABC-transporter-ATP-binding-protein
MSASSATDRPFLEVKDLTVRFETDDGIVQAVSGSTFSLKAGQTLGIVGESGSGKSVTSLAVLGLHRTRSNAKVTGEIWLDDKELVTATDEEVRGLRGGKMAMIFQDPLSAMHPYFTVGSQIVEAYRVHHPGVNKKAARERAIDMLARVGIPQPERRFHDYAHQFSGGMRQRAMIAMALVNDPKLLIADEPTTALDVTVQAQILDLIRDLQEEFGSAVIMITHDLGVVAELADEVLVMYGGKVIERGPAVDLFQRPQHPYTWGLLGSMPRLDREVRDRLNPVKGSPPSLINLPDGCAFHPRCPYAGRNGDRSFKEVPILSGGTHGVACHLPPDLRTKIFQEEVLPNL
>NC_017093.1|WP_014447948.1|8479349_8480387_-|dipeptide-ABC-transporter-ATP-binding-protein
MSENLLEATGVQKHFPITKGLFKRQIGAVRAVDGIDLNVRAGETLGLVGESGCGKSTLGRLFTRILEPTDGKIVFEGEDITHKSVTQMRPLRRDVQMIFQDPYSSLNPRHTVGSIISAPLQIQNIPTPNGLKTAVQELLELVGLNPEHYNRYPHEFSGGQRQRIGIARALALKPKLIVADEPVSALDVSIQAQVVNLLEDLQNEFDLTYVFIAHDLSVVRHISDRVAVMYLGKVVEIAERDELYKNPRHPYTVALMSAVPVPDPVRRDRAQRERVLLTGDVPSPINPPSGCRFRTRCWKAQDICATEEPPLVTRLDDPESHLTACHFPVVSDETVAGRRSAATPA
>NC_017093.1|WP_014447947.1|8477477_8479247_+|calcium-binding-protein
MSRSQWLTHVGVALLTTVAIGATGSPAFAAGTGTVSVSGTSQIVFKAGSGKVNTLRISRSGRTVTVNDGVTLKAGKGCKQVKNDRTQVRCTTKKTPALITAYLGDKNDSLTGNLGTPLKVYGGSGNDRLTGGSGNDRIVGESGNDRVYGAAGNDSLDGGTGNDRIVGNQGHDKVWGGAGDDSILGHDGDDTLYGDAGNDVIEGSWGTDKVWGGSGNDRLGGGDGNDRLDGGAGADALTGANGHDSLYGSSGNDSIDGGTGNDTLHGGDGDDALKGGTDRDKEYGGAGNDRFLQSSLSSGDDDLFVGNAGNDEVSYVSRTNPVYLSNNGVSRDDGARRNLNDKWVQVEFDTISTDVESLVGGAGHDRIFGGRHADILTGGRGSDLLDGGDGNDVLYGGGRTGVPDEGNELFNNTLIGGAGDDRLFGGAANDVLIGDYNTPSDIPRPVGTDRLDGGSGDNTVSYQYAGSRVAVLALQRGSSSENGEKDENDYIRNAGGIIGSGYDDELTGGGGYHTDFRGGAGNDVMRALTAGSQLMGGTGEDRIYGGPATSSWGDSLYVDDHVKDELIGGTHCNVFPLDEASGCELVHQN
>NC_017093.1|WP_014447946.1|8474996_8477303_+|calcium-binding-protein
MSRSQWLTRIGVALFTTIAVGAVGTPAFAASTGTASVSGKSTVVFKAGSGRTNSVKITRSLRTITIDDKVAVKAGKGCKPVKGDKTKVRCTPYMTPTLVRAYLGDRNDVLVSTAGTPLKAYGGSGDDKITGSSGADRLVGDSGNDQIWGAAGNDSLDGGTGNDRVKGGTGNDKLYGSAGNDTVNGESGNDSLDGGSGNDSIAGSTGNDNELGGTGNDTFVQGGNGRADRDVIRGQAGRDTVSYATRTGTVWISTDTTKADDGEAGERDTVHPDIEVLVGGRGADFLRGGGNATAFYGGDGNDHLVASAHHSLLDGGNGRDRVFGGQGNDTLRGGNDNDELIGWSGNDLLDGGNGDDYLAGDDPDLESSSARGNDVLRGGPGSDRVDYNGNSKPVTVDLDGATGDDGQAGEHDTVGSDVERLIGSPQSDVLTGNSAANHIVGGFGDDVIRGGGGNDTLSGEDGADRVFGETGDDTLQGGNGNDVLTGDSGNDKEYGDAGDDTFRQPQASGADADTFAGGTGTDFVDYSYRTTSSVTLSLNGVKGDDGGDSEGDTLPADVEVLAGSALGGDTIRGSSGNDTLHGCGFGDKIYGEGGDDVIHGEGVCSATAERDSIEPQGSYLVGGAGDDKITGTKYSDRFFGDYDTPSDTPRPAGVDTLIGTSGSNGSDYDDDAADYRYASGPVITGNVPTGKTGERDKLSGISIVFGSEFDDVLALDADYHWVYDPTLYGLGGDDELYGGTATWLNGGDGTDLCRLSETSTGEKRNCEL
>NC_017093.1|WP_157435556.1|8474484_8474850_+|hypothetical-protein
MVHVRQGLGNREDLLEADRHREGEGGARRHAGDLLMASPEKSLTTDIVPGPGGVMTDEVGVVTGDLTLRTEISGGDVVLRVQYKDAEEWYAVTGGKAPLADPADLEAVHSIAVGLLNRPGG
>NC_017093.1|WP_157435209.1|8490794_8491658_+|hypothetical-protein
MCPVSDKRHVQTRIDILRQILLLSYRSWRLEQIHWGDALKRTRKAVTNVLIAALTASAIAIFADASAAHAGPDDPGTGGPGSGGQPTAPPSAVVPEVIGNDSDGNPVYSTGGNGIVDPAEDSDSLSDEPFAEVPETEGKPDATTQGTGETCPAKTTGTVRNIPNSLKVDWADSVINRTSGKVSYTVKAETSKKFTWSVGASVSGEGKLWIFAKVSATINGNIAHEKSTIYGSSITVEVPAHKTMKADRGMWQEKFSYKYKTTTKNCSWKSGSGTGWAPYRQAWHVYS
>NC_017093.1|WP_014447957.1|8491993_8492293_+|hypothetical-protein
MSGSGSAQTPPFQVDEKLFTVRIACIGGGELQLFQGEEKVEVSCDGSTRRVHVNTDAKEERVPITASAKQEWTVSIVVTKDFSTAGATPTADPSASALG
>NC_017093.1|WP_157435210.1|8492587_8493910_-|hypothetical-protein
MRYFDTDDRLVACMSCQVGADVFFVTAAYPVSYEFDSWSLGSGLSDAPGCADSPASVAYGFGPVTGTLTPARRAWCQVLPVRPGDRFRVSVQSSAAVLPAALMLSPDGTALPCDYAYDPRDGYSCTPRFASGQTRGAAVIAVTADATAPVPFTVQASCATGLCDGNTYSLHPAEQINVTAGRKATFEIAGTSLHTGDTVRLTRAGHASIPGTVRSVSANRYRMTVEADFAKAAPGKWNIVGASYSSASRTAQLNNLVNVLPMPKIVVKAKPSVVGKAAVGLRVRATTGTWSVKPASVRYQWTADGVAIKGATGSAYTIPASLRGKRIAVIVTARAAGHTDTASSSAAVTVGYGVVPKATKKPSISGTVKAGKTVKVKVGAWSPSATSYKYVWRVDGKVVGTGSKVKLKKSWKGKKLTVTVTAKRAGHYDGKATSKALKIK
>NC_017093.1|WP_041830341.1|8493809_8495039_-|hypothetical-protein
MAVAVSGVPLPASAAPAAPAVLAGLPAAIDPATCPEVTPGAFGAAPAGPLGGGDCRRLVVETAGRHMVQAVDERNVPQDLQVYDGDGEPICSRLWCDLATGTYTLVADVTTAFATTFVPLQGGGCVPAAGRGYTEAQTRQTIDTAGQVNCLEVAGGAGTYQAALPENERNAWPYFDLVQPSGTVGCRTLITSGCALSGGERLITMMPEGRRSGGYVFALQRVTGSTGCPELPAGDFGDPRGASVAFTGDDFIACFTAAGHTPREIISVSRSGADDAFASLRVLGPNGAPVCGAASWSPAPLAGCQLPETGPYTVVVRSQSAGGGKYLTARVDASGTNCGKRASTDFGGVATRGSLRLGEIHCYRNDLSWVHARGCGGAVLRHRRPACRVHVLPGRRGRVLRDRRVPGLL
>NC_017093.1|WP_014447960.1|8495195_8495537_-|STAS-domain-containing-protein
MRAIVIEHRSDVAVLQLCGELDADTAARLYTALADLLERPVPRIVVDLTALKFCDSVGLSAFITSKQVIAARGGWLSFAGADPFLAQLLETVGLGRYFAIFPEVEDAIAAAQL
>NC_017093.1|WP_014447961.1|8495731_8495941_-|hypothetical-protein
MRVQHHWWNGDLRLQRRDVYIRTDGETWEVEAQLGGPEGKSKVQQCPGRASAMILADAWRGPRWQWREL
>NC_017093.1|WP_014447962.1|8496490_8497204_+|purine-nucleoside-phosphorylase
MSVHIGGKPGDIAERVLLPGDPMRAKWIAETFLEDAVCYTQVRGMLGFTGTWKGERVSVQGSGMGMPSASIYTHELINEYGVKSVIRIGSCGALADDLNLGDVIAAIGSSTDSNMNRYRFEGVVDYAPVADFGLLRTAVEKGEAAGIPIRVGQILAADTFYNDRPDITDRLADYGILAVEMESAAIYTIAARYKAKALTILTVSDHIKRGEAMDSAQREQGFSNMVKIGLDTAIAGA
>NC_017093.1|WP_051042645.1|8497230_8497683_-|nucleoside-deaminase
MRRALAVASASPADVPVGAVLLGPDGTELAAAGNERELSGDPTAHAEVLVLRQAAARLGSWRLDGCALVVTLEPCTMCAGALVLARVGTVVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVYSGVLEDECAALLREFFRSEGAAGDRTLGG
>NC_017093.1|WP_014447964.1|8497709_8498219_-|tRNA-adenosine-deaminase-associated-protein
MSIFAAAVSRTKSGWTASELDLSGLADIDEVVDALRDAEPDADLALLFVESDDEYLAILRLDEGEDLRVFASDSAFAEESRIGSVLLGEVETPALGLDDLAARDDDEERPAAEPDADPIGDAELLGDLGVNAQRLLALCGMEGMLPSDVTAEICQKIGCGDEMEELREA
>NC_017093.1|WP_172666650.1|8498308_8498476_-|hypothetical-protein
MAPSPERLDPERCRRRQELLAALAQAKSVRESDPSQRMRGVRLRELIATRRRPAN

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_017093_7	7.1|2021918|39|NC_017093|CRISPRCasFinder	2021918-2021956	39	NC_017093.1	2021886-2021924	0	1.0
NC_017093_20	20.14|6561758|39|NC_017093|CRT	6561758-6561796	39	NC_017093.1	6562373-6562411	0	1.0
NC_017093_24	24.2|7049190|28|NC_017093|CRISPRCasFinder	7049190-7049217	28	NC_017093.1	7049226-7049253	0	1.0
NC_017093_10	10.2|3800040|25|NC_017093|CRISPRCasFinder	3800040-3800064	25	NC_017093.1	3800076-3800100	1	0.96
NC_017093_13	13.2|4002963|29|NC_017093|CRISPRCasFinder	4002963-4002991	29	NC_017093.1	4002999-4003027	2	0.931
NC_017093_20	20.12|6561617|39|NC_017093|CRT	6561617-6561655	39	NC_017093.1	6562373-6562411	2	0.949

1. spacer 7.1|2021918|39|NC_017093|CRISPRCasFinder matches to position: 2021886-2021924, mismatch: 0, identity: 1.0

gcgccgagccgtagcccaagcaggttcccggggcgccga	CRISPR spacer
gcgccgagccgtagcccaagcaggttcccggggcgccga	Protospacer
***************************************

2. spacer 20.14|6561758|39|NC_017093|CRT matches to position: 6562373-6562411, mismatch: 0, identity: 1.0

ccaccgcggtcgccgccaccctggaaaccaccacggtca	CRISPR spacer
ccaccgcggtcgccgccaccctggaaaccaccacggtca	Protospacer
***************************************

3. spacer 24.2|7049190|28|NC_017093|CRISPRCasFinder matches to position: 7049226-7049253, mismatch: 0, identity: 1.0

agccaagacggccagcgcagccaagacg	CRISPR spacer
agccaagacggccagcgcagccaagacg	Protospacer
****************************

4. spacer 10.2|3800040|25|NC_017093|CRISPRCasFinder matches to position: 3800076-3800100, mismatch: 1, identity: 0.96

cggtgccgccccggatgtcggtgcc	CRISPR spacer
cggtgccgccccggatgtcgctgcc	Protospacer
******************** ****

5. spacer 13.2|4002963|29|NC_017093|CRISPRCasFinder matches to position: 4002999-4003027, mismatch: 2, identity: 0.931

gcgactcaacccgtcaacgcgactcgaca	CRISPR spacer
gcgactcgacacgtcaacgcgactcgaca	Protospacer
*******.** ******************

6. spacer 20.12|6561617|39|NC_017093|CRT matches to position: 6562373-6562411, mismatch: 2, identity: 0.949

ccaccgcggtcgccgccaccctggtaaccgccacggtca	CRISPR spacer
ccaccgcggtcgccgccaccctggaaaccaccacggtca	Protospacer
************************ ****.*********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017093_20	20.22|6562271|24|NC_017093|CRT	6562271-6562294	24	NZ_CP030863	Streptomyces globosus strain LZH-48 plasmid unnamed1, complete sequence	109072-109095	2	0.917
NC_017093_20	20.22|6562271|24|NC_017093|CRT	6562271-6562294	24	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	753757-753780	3	0.875
NC_017093_20	20.22|6562271|24|NC_017093|CRT	6562271-6562294	24	NC_021911	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence	1081842-1081865	3	0.875
NC_017093_20	20.22|6562271|24|NC_017093|CRT	6562271-6562294	24	NZ_CP033582	Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence	44754-44777	3	0.875
NC_017093_20	20.22|6562271|24|NC_017093|CRT	6562271-6562294	24	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1802984-1803007	3	0.875
NC_017093_5	5.1|1713721|27|NC_017093|CRISPRCasFinder	1713721-1713747	27	NZ_CP023549	Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence	728578-728604	4	0.852
NC_017093_5	5.1|1713721|27|NC_017093|CRISPRCasFinder	1713721-1713747	27	NC_017791	Deinococcus gobiensis I-0 plasmid P2, complete sequence	285190-285216	4	0.852
NC_017093_10	10.1|3799986|25|NC_017093|CRISPRCasFinder	3799986-3800010	25	NZ_CP018233	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed5, complete sequence	33897-33921	4	0.84
NC_017093_10	10.2|3800040|25|NC_017093|CRISPRCasFinder	3800040-3800064	25	NZ_CP029832	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence	580799-580823	4	0.84
NC_017093_10	10.2|3800040|25|NC_017093|CRISPRCasFinder	3800040-3800064	25	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	814611-814635	4	0.84
NC_017093_10	10.2|3800040|25|NC_017093|CRISPRCasFinder	3800040-3800064	25	NZ_CP021468	Komagataeibacter europaeus strain SRCM101446 plasmid pKE1446-1	285237-285261	4	0.84
NC_017093_12	12.1|3932397|26|NC_017093|CRISPRCasFinder	3932397-3932422	26	NZ_CP024936	Paraburkholderia graminis strain PHS1 plasmid pPHS1_P, complete sequence	141873-141898	4	0.846
NC_017093_14	14.1|4150342|27|NC_017093|CRISPRCasFinder	4150342-4150368	27	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	684560-684586	4	0.852
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP020385	Rhodovulum sp. MB263 plasmid pRSMBA, complete sequence	118237-118263	4	0.852
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	795031-795057	4	0.852
NC_017093_20	20.22|6562271|24|NC_017093|CRT	6562271-6562294	24	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5697291-5697314	4	0.833
NC_017093_20	20.22|6562271|24|NC_017093|CRT	6562271-6562294	24	MH632120	Mycobacterium phage Thonko, complete genome	2033-2056	4	0.833
NC_017093_5	5.1|1713721|27|NC_017093|CRISPRCasFinder	1713721-1713747	27	NZ_CP034475	Pantoea agglomerans strain CFSAN047154 plasmid pCFSAN047154_1, complete sequence	174387-174413	5	0.815
NC_017093_5	5.1|1713721|27|NC_017093|CRISPRCasFinder	1713721-1713747	27	NZ_CP034470	Pantoea agglomerans strain CFSAN047153 plasmid pCFSAN047153_1, complete sequence	19351-19377	5	0.815
NC_017093_5	5.1|1713721|27|NC_017093|CRISPRCasFinder	1713721-1713747	27	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	72481-72507	5	0.815
NC_017093_14	14.1|4150342|27|NC_017093|CRISPRCasFinder	4150342-4150368	27	NZ_CP021368	Acidovorax carolinensis strain P4 plasmid pACP4.2, complete sequence	69351-69377	5	0.815
NC_017093_14	14.1|4150342|27|NC_017093|CRISPRCasFinder	4150342-4150368	27	NZ_CP021649	Acidovorax sp. T1 plasmid p1-T1, complete sequence	92750-92776	5	0.815
NC_017093_14	14.1|4150342|27|NC_017093|CRISPRCasFinder	4150342-4150368	27	NZ_CP021364	Acidovorax carolinensis strain P3 plasmid pACP3.2, complete sequence	88427-88453	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	867563-867589	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	1227338-1227364	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	469332-469358	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	222229-222255	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	829107-829133	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	126588-126614	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	486324-486350	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP021355	Rhodococcus sp. S2-17 plasmid pRB98, complete sequence	640751-640777	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	MN234174	Mycobacterium phage Efra2, complete genome	61202-61228	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	MN234201	Mycobacterium phage Guanica15, complete genome	60891-60917	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_LR594668	Variovorax sp. SRS16 plasmid 3	503800-503826	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	6370-6396	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	6000799-6000825	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	844917-844943	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	468865-468891	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP013631	Rhizobium sp. N324 plasmid pRspN324a, complete sequence	286115-286141	5	0.815
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP006993	Methylobacterium sp. AMS5 plasmid pAMS5a, complete sequence	33670-33696	5	0.815
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	867563-867589	5	0.815
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	469332-469358	5	0.815
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	126588-126614	5	0.815
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	61297-61323	5	0.815
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	NZ_CP044283	Rhodococcus erythropolis strain X5 plasmid pRhX5, complete sequence	310827-310853	5	0.815
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	667054-667080	5	0.815
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	NZ_CP006993	Methylobacterium sp. AMS5 plasmid pAMS5a, complete sequence	33670-33696	5	0.815
NC_017093_20	20.10|6561488|27|NC_017093|CRT	6561488-6561514	27	MG593803	Streptomyces phage Rowa, complete genome	4117-4143	5	0.815
NC_017093_24	24.2|7049190|28|NC_017093|CRISPRCasFinder	7049190-7049217	28	NZ_CP009293	Novosphingobium pentaromativorans US6-1 plasmid pLA4, complete sequence	297044-297071	5	0.821
NC_017093_24	24.2|7049190|28|NC_017093|CRISPRCasFinder	7049190-7049217	28	NC_014957	Isosphaera pallida ATCC 43644 plasmid pISOP01, complete sequence	34898-34925	5	0.821
NC_017093_24	24.2|7049190|28|NC_017093|CRISPRCasFinder	7049190-7049217	28	NZ_CP034814	Paracoccus sp. Arc7-R13 plasmid unnamed4, complete sequence	31818-31845	5	0.821
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP023549	Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence	62224-62254	5	0.839
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	580284-580314	5	0.839
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP033582	Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence	445595-445625	5	0.839
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NC_021911	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence	163310-163340	5	0.839
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NC_021911	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence	164279-164309	5	0.839
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP014802	Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence	15362-15392	5	0.839
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP022424	Vitreoscilla filiformis strain ATCC 15551 plasmid pVF1, complete sequence	131028-131058	5	0.839
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP014802	Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence	46533-46563	5	0.839
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP017947	Bosea sp. Tri-49 plasmid unnamed1, complete sequence	29538-29568	5	0.839
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP017947	Bosea sp. Tri-49 plasmid unnamed1, complete sequence	35760-35790	5	0.839
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	591914-591944	5	0.839
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	592850-592880	5	0.839
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	594722-594752	5	0.839
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	595658-595688	5	0.839
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP024310	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence	1433056-1433086	5	0.839
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP023064	Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence	1249179-1249209	5	0.839
NC_017093_5	5.1|1713721|27|NC_017093|CRISPRCasFinder	1713721-1713747	27	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	310709-310735	6	0.778
NC_017093_5	5.1|1713721|27|NC_017093|CRISPRCasFinder	1713721-1713747	27	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1530101-1530127	6	0.778
NC_017093_5	5.1|1713721|27|NC_017093|CRISPRCasFinder	1713721-1713747	27	AP021850	Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome	137759-137785	6	0.778
NC_017093_6	6.1|1745772|29|NC_017093|CRISPRCasFinder	1745772-1745800	29	NC_010851	Streptomyces sp. FR1 plasmid pFRL1, complete sequence	25938-25966	6	0.793
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NC_011368	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence	115121-115152	6	0.812
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	955150-955181	6	0.812
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	2320788-2320819	6	0.812
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	CP053333	Salmonella enterica subsp. diarizonae serovar 47:k:z35 strain 2009K1094 plasmid unnamed1, complete sequence	32230-32261	6	0.812
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP016620	Microvirga ossetica strain V5/3m plasmid unnamed4, complete sequence	307522-307553	6	0.812
NC_017093_14	14.1|4150342|27|NC_017093|CRISPRCasFinder	4150342-4150368	27	NZ_CP053710	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed2, complete sequence	325514-325540	6	0.778
NC_017093_14	14.1|4150342|27|NC_017093|CRISPRCasFinder	4150342-4150368	27	LN997845	Streptomyces reticuli genome assembly TUE45, plasmid : IV	8705-8731	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP050107	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b1, complete sequence	91634-91660	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP050112	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b5, complete sequence	91633-91659	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP010990	Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence	189906-189932	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP010990	Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence	225164-225190	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP012185	Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence	121651-121677	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP012185	Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence	628261-628287	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP012185	Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence	819463-819489	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP012185	Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence	305627-305653	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP012186	Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence	126587-126613	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5465127-5465153	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP012182	Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence	45006-45032	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP012182	Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence	738323-738349	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP012182	Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence	743063-743089	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP012182	Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence	228998-229024	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP012182	Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence	420281-420307	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	MK411746	Arthrobacter phage Sonali, complete genome	2187-2213	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP013516	Rhizobium sp. N1314 plasmid pRspN1314e, complete sequence	493005-493031	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP012183	Pseudonocardia sp. EC080610-09 plasmid pBCI2-2, complete sequence	91079-91105	6	0.778
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_LR594663	Variovorax sp. RA8 plasmid 2	102542-102568	6	0.778
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	NC_023283	Streptomyces sp. FR1 plasmid pFRL3, complete sequence	188209-188235	6	0.778
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	NC_023284	Streptomyces sp. F2 plasmid pFRL4, complete sequence	224837-224863	6	0.778
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	NC_011961	Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence	471414-471440	6	0.778
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	308531-308557	6	0.778
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	NZ_CP018075	Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence	85056-85082	6	0.778
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	NZ_CP030829	Neorhizobium sp. NCHU2750 plasmid pNCHU2750b, complete sequence	36952-36978	6	0.778
NC_017093_20	20.6|6561260|30|NC_017093|CRT	6561260-6561289	30	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1636196-1636225	6	0.8
NC_017093_20	20.6|6561260|30|NC_017093|CRT	6561260-6561289	30	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	395898-395927	6	0.8
NC_017093_20	20.6|6561260|30|NC_017093|CRT	6561260-6561289	30	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	258570-258599	6	0.8
NC_017093_20	20.6|6561260|30|NC_017093|CRT	6561260-6561289	30	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	170365-170394	6	0.8
NC_017093_20	20.10|6561488|27|NC_017093|CRT	6561488-6561514	27	NC_006462	Thermus thermophilus HB8 plasmid pTT27, complete sequence	57334-57360	6	0.778
NC_017093_20	20.10|6561488|27|NC_017093|CRT	6561488-6561514	27	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	322386-322412	6	0.778
NC_017093_24	24.2|7049190|28|NC_017093|CRISPRCasFinder	7049190-7049217	28	NZ_CP037902	Cupriavidus metallidurans strain BS1 plasmid p1, complete sequence	326028-326055	6	0.786
NC_017093_24	24.2|7049190|28|NC_017093|CRISPRCasFinder	7049190-7049217	28	LC473083	Cutibacterium acnes TP-CU389 plasmid pTZC1 DNA, complete sequence	7459-7486	6	0.786
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	1620959-1620989	6	0.806
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	585462-585492	6	0.806
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	553419-553449	6	0.806
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP039899	Agrobacterium tumefaciens strain CFBP5877 plasmid pAtCFBP5877a, complete sequence	41963-41993	6	0.806
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP039890	Agrobacterium tumefaciens strain CFBP5499 plasmid pAtCFBP5499a, complete sequence	41963-41993	6	0.806
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP015094	Pelagibaca abyssi strain JLT2014 plasmid pPABY6, complete sequence	51028-51058	6	0.806
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP014802	Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence	16097-16127	6	0.806
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP018229	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence	535630-535660	6	0.806
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP010865	Marinovum algicola DG 898 plasmid pMaD10, complete sequence	12580-12610	6	0.806
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP023976	Streptomyces alboflavus strain MDJK44 plasmid pMDJK44.1, complete sequence	186079-186109	6	0.806
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NC_016623	Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence	312146-312176	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP010598	Phaeobacter inhibens strain P10 plasmid pP10_c, complete sequence	18150-18180	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NC_018288	Phaeobacter inhibens DSM 17395 plasmid pPGA1_65, complete sequence	48192-48222	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP014802	Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence	49318-49348	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP014802	Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence	51197-51227	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP014802	Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence	137009-137039	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP014802	Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence	16097-16127	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP019311	Phaeobacter inhibens strain DOK1-1 plasmid pDOK1-1-4, complete sequence	54099-54129	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	593786-593816	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP030772	Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence	318150-318180	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP013855	Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence	180294-180324	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1785858-1785888	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1786794-1786824	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1787730-1787760	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1788666-1788696	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	2165358-2165388	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	1155007-1155037	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	1023563-1023593	6	0.806
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	2238020-2238050	6	0.806
NC_017093_1	1.1|191082|31|NC_017093|CRISPRCasFinder	191082-191112	31	NZ_CP044073	Pseudomonas oryzihabitans strain FDAARGOS_657 plasmid unnamed2, complete sequence	147108-147138	7	0.774
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NC_020894	Streptomyces hygroscopicus subsp. jinggangensis TL01 plasmid pSHJGH1, complete sequence	36406-36438	7	0.788
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NC_017766	Streptomyces hygroscopicus subsp. jinggangensis 5008 plasmid pSHJG1, complete sequence	36407-36439	7	0.788
NC_017093_6	6.1|1745772|29|NC_017093|CRISPRCasFinder	1745772-1745800	29	NZ_CP022566	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK02, complete sequence	385637-385665	7	0.759
NC_017093_8	8.1|2539069|33|NC_017093|CRISPRCasFinder	2539069-2539101	33	NZ_CP039644	Azospirillum sp. TSA2s plasmid p2, complete sequence	142275-142307	7	0.788
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP021372	Rhizobium sp. ACO-34A plasmid pRACO34Ad, complete sequence	173819-173850	7	0.781
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	39569-39595	7	0.741
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_CP024895	Amycolatopsis sp. AA4 plasmid unnamed1, complete sequence	146687-146713	7	0.741
NC_017093_20	20.3|6561113|27|NC_017093|CRT	6561113-6561139	27	NZ_LR134461	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 19, complete sequence	141213-141239	7	0.741
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	MN096378	Microbacterium phage MCubed, complete genome	8417-8443	7	0.741
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	MH513982	Microbacterium phage Sansa, complete genome	8413-8439	7	0.741
NC_017093_20	20.6|6561260|30|NC_017093|CRT	6561260-6561289	30	CP000666	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA05, complete sequence	9544-9573	7	0.767
NC_017093_20	20.6|6561260|30|NC_017093|CRT	6561260-6561289	30	NZ_CP011665	Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence	494735-494764	7	0.767
NC_017093_20	20.6|6561260|30|NC_017093|CRT	6561260-6561289	30	NZ_CP024308	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3a, complete sequence	15357-15386	7	0.767
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP015006	Aminobacter aminovorans strain KCTC 2477 plasmid pAA01, complete sequence	185837-185867	7	0.774
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NC_020548	Azoarcus sp. KH32C plasmid pAZKH, complete sequence	482467-482497	7	0.774
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP024310	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence	95094-95124	7	0.774
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP023064	Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence	98677-98707	7	0.774
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1642417-1642447	7	0.774
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1659963-1659993	7	0.774
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1625298-1625328	7	0.774
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	359290-359320	7	0.774
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	359266-359296	7	0.774
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	359073-359103	7	0.774
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	359060-359090	7	0.774
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	169018-169048	7	0.774
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP019319	Tateyamaria omphalii strain DOK1-4 plasmid pDOK1-4-7, complete sequence	19211-19241	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	589362-589392	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP014802	Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence	52526-52556	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP054022	Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence	274721-274751	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP054022	Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence	766528-766558	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP054032	Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence	436306-436336	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP032341	Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence	695653-695683	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP014598	Yangia sp. CCB-MM3 plasmid unnamed2, complete sequence	16752-16782	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP014598	Yangia sp. CCB-MM3 plasmid unnamed2, complete sequence	269158-269188	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	693139-693169	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP033315	Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence	691327-691357	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	118349-118379	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	72725-72755	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP029831	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence	197693-197723	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	936111-936141	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP012916	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence	352953-352983	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	225220-225250	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP017947	Bosea sp. Tri-49 plasmid unnamed1, complete sequence	28944-28974	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	227349-227379	7	0.774
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NC_013857	Azospirillum sp. B510 plasmid pAB510c, complete sequence	566726-566756	7	0.774
NC_017093_25	25.3|8477978|31|NC_017093|CRISPRCasFinder	8477978-8478008	31	NC_016585	Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence	316130-316160	7	0.774
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP010678	Phaeobacter gallaeciensis strain P75 plasmid pP75_e, complete sequence	18151-18181	7	0.774
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1784559-1784589	7	0.774
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP016368	Phaeobacter porticola strain P97 plasmid pP97_d, complete sequence	18198-18228	7	0.774
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP010642	Phaeobacter gallaeciensis strain P73 plasmid pP73_f, complete sequence	18151-18181	7	0.774
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP029359	Azospirillum sp. CFH 70021 plasmid unnamed4	80599-80629	7	0.774
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	186448-186478	7	0.774
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	620337-620367	7	0.774
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP033315	Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence	17179-17209	7	0.774
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	ASHF01000034	Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence	8718-8748	7	0.774
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	MK977704	Gordonia Terrae phage RoadKill, complete genome	25705-25735	7	0.774
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	MT498054	Gordonia Phage Engineer, complete genome	64136-64168	8	0.758
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	MK376959	Gordonia phage Aphelion, complete genome	64505-64537	8	0.758
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	KU998244	Gordonia phage Smoothie, complete genome	63974-64006	8	0.758
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	KU998247	Gordonia phage Bachita, complete genome	64163-64195	8	0.758
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	MF919520	Gordonia phage Lozinak, complete genome	63974-64006	8	0.758
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	47838-47869	8	0.75
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	49069-49100	8	0.75
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	49065-49096	8	0.75
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	338503-338534	8	0.75
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	49069-49100	8	0.75
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	50402-50433	8	0.75
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	50402-50433	8	0.75
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP032695	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence	356280-356311	8	0.75
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	49079-49110	8	0.75
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	49110-49141	8	0.75
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	49069-49100	8	0.75
NC_017093_13	13.2|4002963|29|NC_017093|CRISPRCasFinder	4002963-4002991	29	LR026998	unidentified phage genome assembly, chromosome: 1	3979-4007	8	0.724
NC_017093_13	13.2|4002963|29|NC_017093|CRISPRCasFinder	4002963-4002991	29	NC_048666	Salmonella phage YSD1 strain YSD1_PHAGE genome assembly	3979-4007	8	0.724
NC_017093_20	20.6|6561260|30|NC_017093|CRT	6561260-6561289	30	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	173537-173566	8	0.733
NC_017093_20	20.6|6561260|30|NC_017093|CRT	6561260-6561289	30	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	612171-612200	8	0.733
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	1540940-1540970	8	0.742
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	486123-486153	8	0.742
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	1158559-1158589	8	0.742
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	2164953-2164983	8	0.742
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	375433-375463	8	0.742
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP018096	Chelatococcus daeguensis strain TAD1 plasmid pTAD1, complete sequence	127778-127808	8	0.742
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP026305	Streptomyces lunaelactis strain MM109 plasmid pSLUN1, complete sequence	84351-84381	8	0.742
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP014802	Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence	46371-46401	8	0.742
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP054022	Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence	766474-766504	8	0.742
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP054032	Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence	436252-436282	8	0.742
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NC_007949	Polaromonas sp. JS666 plasmid 1, complete sequence	28967-28997	8	0.742
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	360329-360359	8	0.742
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	JQ807251	Environmental Halophage eHP-32, partial genome	444-474	8	0.742
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP014802	Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence	48994-49024	8	0.742
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP036297	Planctomycetes bacterium Pla86 plasmid pPla86_1, complete sequence	26178-26208	8	0.742
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP036288	Planctomycetes bacterium Pla133 plasmid pPla133_1, complete sequence	26208-26238	8	0.742
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NC_014502	Gloeothece verrucosa PCC 7822 plasmid Cy782203, complete sequence	40470-40500	8	0.742
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	1218456-1218486	8	0.742
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP017244	Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence	1942038-1942068	8	0.742
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	KX241618	Xanthomonas phage Xoo-sp2, complete genome	48857-48887	8	0.742
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	KX557276	Gordonia phage Cucurbita, complete genome	64670-64702	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1733080-1733112	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	1812034-1812066	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1820252-1820284	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	1655114-1655146	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	1838277-1838309	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	1870786-1870818	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	1897482-1897514	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	2041730-2041762	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	1523115-1523147	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	1802395-1802427	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	412914-412946	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	775372-775404	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	1880271-1880303	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	1725332-1725364	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	1589038-1589070	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	1819347-1819379	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	1817161-1817193	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	1654136-1654168	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1733152-1733184	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1733153-1733185	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	1814218-1814250	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	1886218-1886250	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	1655107-1655139	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	1654428-1654460	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	1655096-1655128	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	1757027-1757059	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	1815575-1815607	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	1891751-1891783	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	1886185-1886217	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	1792507-1792539	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	1870006-1870038	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	1884928-1884960	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	1782658-1782690	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	1792819-1792851	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	1870006-1870038	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	1885027-1885059	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	1792507-1792539	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1733248-1733280	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	1783305-1783337	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	1791710-1791742	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	1870006-1870038	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	1870006-1870038	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	1870006-1870038	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	1885023-1885055	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	1943600-1943632	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	1885012-1885044	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	1782681-1782713	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	1796981-1797013	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1733246-1733278	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	1777618-1777650	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	1837512-1837544	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	1869500-1869532	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	1867321-1867353	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	1885012-1885044	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	1782681-1782713	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	1792818-1792850	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	1819927-1819959	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	1886009-1886041	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	1782681-1782713	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	1782681-1782713	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	1885023-1885055	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	1870011-1870043	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	1885034-1885066	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	1884835-1884867	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1733225-1733257	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	828517-828549	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	247492-247524	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	833569-833601	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	22559-22591	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1090543-1090575	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	615045-615077	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	494435-494467	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	593030-593062	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	1286353-1286385	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	132485-132517	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	132485-132517	9	0.727
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NC_030901	Gordonia phage ClubL, complete genome	63093-63125	9	0.727
NC_017093_8	8.1|2539069|33|NC_017093|CRISPRCasFinder	2539069-2539101	33	NC_020894	Streptomyces hygroscopicus subsp. jinggangensis TL01 plasmid pSHJGH1, complete sequence	75949-75981	9	0.727
NC_017093_8	8.1|2539069|33|NC_017093|CRISPRCasFinder	2539069-2539101	33	NC_017766	Streptomyces hygroscopicus subsp. jinggangensis 5008 plasmid pSHJG1, complete sequence	75950-75982	9	0.727
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	49057-49088	9	0.719
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	49066-49097	9	0.719
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	49066-49097	9	0.719
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	49065-49096	9	0.719
NC_017093_16	16.1|4496518|37|NC_017093|CRISPRCasFinder	4496518-4496554	37	NC_011368	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence	100296-100332	9	0.757
NC_017093_20	20.6|6561260|30|NC_017093|CRT	6561260-6561289	30	NZ_CP042268	Pseudomonas aeruginosa strain HOU1 plasmid pHOU1-1, complete sequence	92002-92031	9	0.7
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1843988-1844018	9	0.71
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP013526	Rhizobium phaseoli strain R744 plasmid pRphaR744d, complete sequence	857147-857177	9	0.71
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP013556	Rhizobium phaseoli strain N931 plasmid pRphaN931d, complete sequence	821530-821560	9	0.71
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP013589	Rhizobium phaseoli strain N161 plasmid pRphaN161d, complete sequence	810280-810310	9	0.71
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP013562	Rhizobium phaseoli strain N841 plasmid pRphaN841e, complete sequence	796821-796851	9	0.71
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP013579	Rhizobium phaseoli strain N671 plasmid pRphaN671e, complete sequence	788888-788918	9	0.71
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP013531	Rhizobium phaseoli strain R723 plasmid pRphaR723d, complete sequence	773061-773091	9	0.71
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP013536	Rhizobium phaseoli strain R650 plasmid pRphaR650d, complete sequence	807927-807957	9	0.71
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NC_011368	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence	408023-408053	9	0.71
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP013541	Rhizobium phaseoli strain R630 plasmid pRphaR630d, complete sequence	809465-809495	9	0.71
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP013546	Rhizobium phaseoli strain R620 plasmid pRphaR620d, complete sequence	803216-803246	9	0.71
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP013567	Rhizobium phaseoli strain N831 plasmid pRphaN831d, complete sequence	821530-821560	9	0.71
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP013584	Rhizobium phaseoli strain N261 plasmid pRphaN261d, complete sequence	773061-773091	9	0.71
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP013573	Rhizobium phaseoli strain N771 plasmid pRphaN771e, complete sequence	788888-788918	9	0.71
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NZ_CP020900	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5d, complete sequence	749986-750016	9	0.71
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	765260-765290	9	0.71
NC_017093_25	25.1|8477870|31|NC_017093|CRISPRCasFinder	8477870-8477900	31	CP007643	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803b, complete sequence	151291-151321	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP050098	Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b4, complete sequence	486479-486509	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	2017318-2017348	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	1488552-1488582	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	1233901-1233931	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	1792479-1792509	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	1496002-1496032	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	1205659-1205689	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	1597010-1597040	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	1507483-1507513	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	1596977-1597007	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	1595771-1595801	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	1595807-1595837	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	1595807-1595837	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP053209	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1A, complete sequence	128489-128519	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	1595796-1595826	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	1413601-1413631	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	1394254-1394284	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	1447510-1447540	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	1486388-1486418	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	1595796-1595826	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	1596797-1596827	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	1595807-1595837	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	1595818-1595848	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	1595619-1595649	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP050084	Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b2, complete sequence	97944-97974	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP022220	Bradyrhizobium guangxiense strain CCBAU 53363 plasmid p53363, complete sequence	820898-820928	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	654530-654560	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	404558-404588	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP031166	Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence	548551-548581	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	1250052-1250082	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP030052	Bradyrhizobium guangdongense strain CCBAU 51649 plasmid unnamed, complete sequence	433738-433768	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	545273-545303	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	NZ_CP030054	Bradyrhizobium guangzhouense strain CCBAU 51670 plasmid unnamed1, complete sequence	613331-613361	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	MT684599	Gordonia Phage Sephiroth, complete genome	51567-51597	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	MH976515	Gordonia phage Octobien14, complete genome	50713-50743	9	0.71
NC_017093_25	25.2|8477924|31|NC_017093|CRISPRCasFinder	8477924-8477954	31	MH727561	Mycobacterium phage Serendipitous, complete genome	46511-46541	9	0.71
NC_017093_25	25.4|8478032|31|NC_017093|CRISPRCasFinder	8478032-8478062	31	NZ_CP048285	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248a, complete sequence	197729-197759	9	0.71
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1971963-1971995	10	0.697
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	1897491-1897523	10	0.697
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	549475-549507	10	0.697
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	578947-578979	10	0.697
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	549500-549532	10	0.697
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	578987-579019	10	0.697
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	436345-436377	10	0.697
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	211802-211834	10	0.697
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	578956-578988	10	0.697
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	549287-549319	10	0.697
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	549277-549309	10	0.697
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	601287-601319	10	0.697
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	432154-432186	10	0.697
NC_017093_4	4.1|1298810|33|NC_017093|CRISPRCasFinder	1298810-1298842	33	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	574810-574842	10	0.697
NC_017093_9	9.1|3315030|34|NC_017093|CRISPRCasFinder	3315030-3315063	34	NZ_CP033323	Azospirillum brasilense strain Cd plasmid p5, complete sequence	13086-13119	10	0.706
NC_017093_9	9.1|3315030|34|NC_017093|CRISPRCasFinder	3315030-3315063	34	NZ_CP012919	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p5, complete sequence	51875-51908	10	0.706
NC_017093_9	9.1|3315030|34|NC_017093|CRISPRCasFinder	3315030-3315063	34	NZ_CP032344	Azospirillum brasilense strain MTCC4038 plasmid p5, complete sequence	131563-131596	10	0.706
NC_017093_9	9.1|3315030|34|NC_017093|CRISPRCasFinder	3315030-3315063	34	NZ_CP033317	Azospirillum brasilense strain Sp 7 plasmid p5, complete sequence	55137-55170	10	0.706
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	CP036421	Rhodobacter sphaeroides strain HJ plasmid unnamed1, complete sequence	61833-61864	10	0.688
NC_017093_11	11.1|3853064|32|NC_017093|CRISPRCasFinder	3853064-3853095	32	NZ_CP014600	Yangia sp. CCB-MM3 plasmid unnamed4, complete sequence	109670-109701	11	0.656
NC_017093_20	20.5|6561215|27|NC_017093|CRT	6561215-6561241	27	NZ_CP039912	Agrobacterium tumefaciens strain CFBP6625 plasmid pAtCFBP6625a, complete sequence	277313-277339	13	0.519

1. spacer 20.22|6562271|24|NC_017093|CRT matches to NZ_CP030863 (Streptomyces globosus strain LZH-48 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.917

ccgccgcggtcgccgctcaccgag	CRISPR spacer
ccggcgcggccgccgctcaccgag	Protospacer
*** *****.**************

2. spacer 20.22|6562271|24|NC_017093|CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 3, identity: 0.875

ccgccgcggtcgccgctcaccgag	CRISPR spacer
acgccgcggtcgccgatcaccgtg	Protospacer
 ************** ****** *

3. spacer 20.22|6562271|24|NC_017093|CRT matches to NC_021911 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence) position: , mismatch: 3, identity: 0.875

ccgccgcggtcgccgctcaccgag	CRISPR spacer
ccgccggggtcgccgctgaccgac	Protospacer
****** ********** ***** 

4. spacer 20.22|6562271|24|NC_017093|CRT matches to NZ_CP033582 (Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence) position: , mismatch: 3, identity: 0.875

ccgccgcggtcgccgctcaccgag	CRISPR spacer
ctaccgcgctcgccgctcaccgag	Protospacer
*..***** ***************

5. spacer 20.22|6562271|24|NC_017093|CRT matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 3, identity: 0.875

ccgccgcggtcgccgctcaccgag	CRISPR spacer
acgccgcggtcgccgatcaccgtg	Protospacer
 ************** ****** *

6. spacer 5.1|1713721|27|NC_017093|CRISPRCasFinder matches to NZ_CP023549 (Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.852

cccgccgggcggcttggctggcgggcg	CRISPR spacer
tcggccggacggcgtggctggcgggcg	Protospacer
.* *****.**** *************

7. spacer 5.1|1713721|27|NC_017093|CRISPRCasFinder matches to NC_017791 (Deinococcus gobiensis I-0 plasmid P2, complete sequence) position: , mismatch: 4, identity: 0.852

cccgccgggcggcttggctggcgggcg	CRISPR spacer
gcagccgggcggcgtggctgccgggcg	Protospacer
 * ********** ****** ******

8. spacer 10.1|3799986|25|NC_017093|CRISPRCasFinder matches to NZ_CP018233 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed5, complete sequence) position: , mismatch: 4, identity: 0.84

gggcgccgtgccgaacccgggccct	CRISPR spacer
gggcgccatgccgaacccgggagca	Protospacer
*******.*************  * 

9. spacer 10.2|3800040|25|NC_017093|CRISPRCasFinder matches to NZ_CP029832 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.84

cggtgccgccccggatgtcggtgcc	CRISPR spacer
ggctgccggcccggatgtcggtgct	Protospacer
 * ***** ***************.

10. spacer 10.2|3800040|25|NC_017093|CRISPRCasFinder matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 4, identity: 0.84

cggtgccgccccggatgtcggtgcc	CRISPR spacer
aggtgccgaccaggatgtcggtgct	Protospacer
 ******* ** ************.

11. spacer 10.2|3800040|25|NC_017093|CRISPRCasFinder matches to NZ_CP021468 (Komagataeibacter europaeus strain SRCM101446 plasmid pKE1446-1) position: , mismatch: 4, identity: 0.84

cggtgccgccccggatgtcggtgcc	CRISPR spacer
gcgtgccgccccgggtgccggtgcc	Protospacer
  ************.**.*******

12. spacer 12.1|3932397|26|NC_017093|CRISPRCasFinder matches to NZ_CP024936 (Paraburkholderia graminis strain PHS1 plasmid pPHS1_P, complete sequence) position: , mismatch: 4, identity: 0.846

acggcccggattcgcgagccgtcgct	CRISPR spacer
tcggcccagaatcgcgagccgtcgcg	Protospacer
 ******.** ************** 

13. spacer 14.1|4150342|27|NC_017093|CRISPRCasFinder matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 4, identity: 0.852

tgtcaccgacgacgggaaggcttgctt	CRISPR spacer
cgtcaccgacgacgggaaggccggcgt	Protospacer
.********************. ** *

14. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP020385 (Rhodovulum sp. MB263 plasmid pRSMBA, complete sequence) position: , mismatch: 4, identity: 0.852

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
tcgacatcgcggtcgcggtcgccaccg	Protospacer
* * **.*******************.

15. spacer 20.5|6561215|27|NC_017093|CRT matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 4, identity: 0.852

tagccaccgcggtcgcggtctccgcca	CRISPR spacer
cggccaccgcggtcacggtcaccgcca	Protospacer
..************.***** ******

16. spacer 20.22|6562271|24|NC_017093|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 4, identity: 0.833

ccgccgcggtcgccgctcaccgag	CRISPR spacer
gggccgcggtcgccgctcaccacg	Protospacer
  *******************. *

17. spacer 20.22|6562271|24|NC_017093|CRT matches to MH632120 (Mycobacterium phage Thonko, complete genome) position: , mismatch: 4, identity: 0.833

ccgccgcggtcgccgctcaccgag	CRISPR spacer
tcgccgcggtcgccgcgcaccgca	Protospacer
.*************** ***** .

18. spacer 5.1|1713721|27|NC_017093|CRISPRCasFinder matches to NZ_CP034475 (Pantoea agglomerans strain CFSAN047154 plasmid pCFSAN047154_1, complete sequence) position: , mismatch: 5, identity: 0.815

cccgccgggcggcttggctggcgggcg	CRISPR spacer
gccgccgggcggctggggtggcggcgg	Protospacer
 ************* ** ******  *

19. spacer 5.1|1713721|27|NC_017093|CRISPRCasFinder matches to NZ_CP034470 (Pantoea agglomerans strain CFSAN047153 plasmid pCFSAN047153_1, complete sequence) position: , mismatch: 5, identity: 0.815

cccgccgggcggcttggctggcgggcg	CRISPR spacer
gccgccgggcggctggggtggcggcgg	Protospacer
 ************* ** ******  *

20. spacer 5.1|1713721|27|NC_017093|CRISPRCasFinder matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 5, identity: 0.815

cccgccgggcggcttggctggcgggcg	CRISPR spacer
ctgaccgggcggttcggctggcgggcg	Protospacer
*. .********.*.************

21. spacer 14.1|4150342|27|NC_017093|CRISPRCasFinder matches to NZ_CP021368 (Acidovorax carolinensis strain P4 plasmid pACP4.2, complete sequence) position: , mismatch: 5, identity: 0.815

tgtcaccgacgacgggaaggcttgctt	CRISPR spacer
gatcaccgacgatgggaatgcttgctg	Protospacer
 .**********.***** ******* 

22. spacer 14.1|4150342|27|NC_017093|CRISPRCasFinder matches to NZ_CP021649 (Acidovorax sp. T1 plasmid p1-T1, complete sequence) position: , mismatch: 5, identity: 0.815

tgtcaccgacgacgggaaggcttgctt	CRISPR spacer
gatcaccgacgatgggaatgcttgctg	Protospacer
 .**********.***** ******* 

23. spacer 14.1|4150342|27|NC_017093|CRISPRCasFinder matches to NZ_CP021364 (Acidovorax carolinensis strain P3 plasmid pACP3.2, complete sequence) position: , mismatch: 5, identity: 0.815

tgtcaccgacgacgggaaggcttgctt	CRISPR spacer
gatcaccgacgatgggaatgcttgctg	Protospacer
 .**********.***** ******* 

24. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
gcagcaccgcggtcgcggtcgccgcca	Protospacer
  . *******************.***

25. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
tcgccaccgctgtcgccgtcgccactt	Protospacer
* ******** ***** ********. 

26. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
gcagcaccgcggtcgcggtcgccgcca	Protospacer
  . *******************.***

27. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
tcgccaccgctgtcgccgtcgccactt	Protospacer
* ******** ***** ********. 

28. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
tcgccaccgctgtcgccgtcgccactt	Protospacer
* ******** ***** ********. 

29. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
gcagcaccgcggtcgcggtcgccgcca	Protospacer
  . *******************.***

30. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
tcgccaccgctgtcgccgtcgccactt	Protospacer
* ******** ***** ********. 

31. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP021355 (Rhodococcus sp. S2-17 plasmid pRB98, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
cggccaccgcgtgcgcggtcgccaccc	Protospacer
..*********  ************* 

32. spacer 20.3|6561113|27|NC_017093|CRT matches to MN234174 (Mycobacterium phage Efra2, complete genome) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
gggccaccgcggtcacggtcgccagta	Protospacer
 .************.********* .*

33. spacer 20.3|6561113|27|NC_017093|CRT matches to MN234201 (Mycobacterium phage Guanica15, complete genome) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
gggccaccgcggtcacggtcgccagta	Protospacer
 .************.********* .*

34. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_LR594668 (Variovorax sp. SRS16 plasmid 3) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
tcgacacctcggtcgcggtcgccacgc	Protospacer
* * **** ****************  

35. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
tagccaccgcggccgcggtcggtgccc	Protospacer
************.******** ..** 

36. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
tagccaccgcggccgcggtcggtgccc	Protospacer
************.******** ..** 

37. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
tgaactccgcggtcgcggccgccacca	Protospacer
*.. * ************.********

38. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
tcgacacctcggtcgcggtcgccacgc	Protospacer
* * **** ****************  

39. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP013631 (Rhizobium sp. N324 plasmid pRspN324a, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
cagccaccgcggttgcggtggccaacc	Protospacer
.************.***** **** * 

40. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP006993 (Methylobacterium sp. AMS5 plasmid pAMS5a, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
tcgccaccgcggtcgcgctcgccgcgc	Protospacer
* *************** *****.*  

41. spacer 20.5|6561215|27|NC_017093|CRT matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtctccgcca	CRISPR spacer
gcagcaccgcggtcgcggtcgccgcca	Protospacer
  . **************** ******

42. spacer 20.5|6561215|27|NC_017093|CRT matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtctccgcca	CRISPR spacer
gcagcaccgcggtcgcggtcgccgcca	Protospacer
  . **************** ******

43. spacer 20.5|6561215|27|NC_017093|CRT matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtctccgcca	CRISPR spacer
gcagcaccgcggtcgcggtcgccgcca	Protospacer
  . **************** ******

44. spacer 20.5|6561215|27|NC_017093|CRT matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtctccgcca	CRISPR spacer
cggccaccgcggtcccggtctccgcgg	Protospacer
..************ ********** .

45. spacer 20.5|6561215|27|NC_017093|CRT matches to NZ_CP044283 (Rhodococcus erythropolis strain X5 plasmid pRhX5, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtctccgcca	CRISPR spacer
acgccaccgcgttcgcggtctgcgccg	Protospacer
  ********* ********* ****.

46. spacer 20.5|6561215|27|NC_017093|CRT matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtctccgcca	CRISPR spacer
cggtcaccgcggcctcggtctccgcca	Protospacer
..*.********.* ************

47. spacer 20.5|6561215|27|NC_017093|CRT matches to NZ_CP006993 (Methylobacterium sp. AMS5 plasmid pAMS5a, complete sequence) position: , mismatch: 5, identity: 0.815

tagccaccgcggtcgcggtctccgcca	CRISPR spacer
tcgccaccgcggtcgcgctcgccgcgc	Protospacer
* *************** ** ****  

48. spacer 20.10|6561488|27|NC_017093|CRT matches to MG593803 (Streptomyces phage Rowa, complete genome) position: , mismatch: 5, identity: 0.815

ccgccaccctggtagccaccgcgatcg	CRISPR spacer
tggccaccctggtagccaccaccattg	Protospacer
. ******************.* **.*

49. spacer 24.2|7049190|28|NC_017093|CRISPRCasFinder matches to NZ_CP009293 (Novosphingobium pentaromativorans US6-1 plasmid pLA4, complete sequence) position: , mismatch: 5, identity: 0.821

agccaagacggccagcgcagccaagacg	CRISPR spacer
gcccaagacggccagcgcagccgcgccg	Protospacer
. ********************. * **

50. spacer 24.2|7049190|28|NC_017093|CRISPRCasFinder matches to NC_014957 (Isosphaera pallida ATCC 43644 plasmid pISOP01, complete sequence) position: , mismatch: 5, identity: 0.821

agccaagacggccagcgcagccaagacg	CRISPR spacer
agccaaggcgtccagcgcagccacgtgg	Protospacer
*******.** ************ *  *

51. spacer 24.2|7049190|28|NC_017093|CRISPRCasFinder matches to NZ_CP034814 (Paracoccus sp. Arc7-R13 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.821

agccaagacggccagcgcagccaagacg	CRISPR spacer
agacatgacggccagcgcagccagtgcg	Protospacer
** ** *****************. .**

52. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP023549 (Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.839

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cggcagcggcaacgaccggatcgacggcagc	Protospacer
*********************** ***... 

53. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 5, identity: 0.839

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cggcagcggcaacgacctgatcgccggcggc	Protospacer
***************** *****.***.*. 

54. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP033582 (Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence) position: , mismatch: 5, identity: 0.839

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgtcaacggcaacgacagcctcgacggcggt	Protospacer
**. . ********************* ***

55. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NC_021911 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence) position: , mismatch: 5, identity: 0.839

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cggcgccggcaacgacatcctcgacggcggc	Protospacer
**  ************* ********* **.

56. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NC_021911 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence) position: , mismatch: 5, identity: 0.839

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cggcgccggcaacgacatcctcgacggcggc	Protospacer
**  ************* ********* **.

57. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP014802 (Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence) position: , mismatch: 5, identity: 0.839

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgatgccggcaacgacatcctcgacggcggg	Protospacer
**  ************* ********* ** 

58. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP022424 (Vitreoscilla filiformis strain ATCC 15551 plasmid pVF1, complete sequence) position: , mismatch: 5, identity: 0.839

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
caacgacggcgacaacaccctcaacggtgca	Protospacer
* ***********.******** ******  

59. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP014802 (Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence) position: , mismatch: 5, identity: 0.839

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggcgacggcgacgacacgctctacggcaac	Protospacer
* .*************** ********..**

60. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP017947 (Bosea sp. Tri-49 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.839

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cgaggacggcgacgacaccctcttcggcgag	Protospacer
* * ******************* ***.** 

61. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP017947 (Bosea sp. Tri-49 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.839

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggcgacggcgacgacaccctcaacggcggc	Protospacer
* .******************* ****.*.*

62. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 5, identity: 0.839

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggcgacggcgacgacaccctcgacggcggc	Protospacer
* .******************* ****.*.*

63. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 5, identity: 0.839

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggcgacggcgacgacaccctcgacggcggc	Protospacer
* .******************* ****.*.*

64. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 5, identity: 0.839

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggcgacggcgacgacaccctcgacggcggc	Protospacer
* .******************* ****.*.*

65. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 5, identity: 0.839

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggcgacggcgacgacaccctcgacggcggc	Protospacer
* .******************* ****.*.*

66. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP024310 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence) position: , mismatch: 5, identity: 0.839

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cgacgacggcaacgacacgctctacggcggc	Protospacer
* ********.******* ********.*.*

67. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP023064 (Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence) position: , mismatch: 5, identity: 0.839

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cgacgacggcaacgacacgctctacggcggc	Protospacer
* ********.******* ********.*.*

68. spacer 5.1|1713721|27|NC_017093|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.778

cccgccgggcggcttggctggcgggcg	CRISPR spacer
ttcgccgggcggcttgacgggcgggtc	Protospacer
..**************.* ******. 

69. spacer 5.1|1713721|27|NC_017093|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 6, identity: 0.778

cccgccgggcggcttggctggcgggcg	CRISPR spacer
tccgccgggcggctggcctggcggcgc	Protospacer
.************* * *******   

70. spacer 5.1|1713721|27|NC_017093|CRISPRCasFinder matches to AP021850 (Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome) position: , mismatch: 6, identity: 0.778

cccgccgggcggcttggctggcgggcg	CRISPR spacer
ccagccgggcggcgtggctggcgttgc	Protospacer
** ********** *********    

71. spacer 6.1|1745772|29|NC_017093|CRISPRCasFinder matches to NC_010851 (Streptomyces sp. FR1 plasmid pFRL1, complete sequence) position: , mismatch: 6, identity: 0.793

cctgtcgtcgaggaggtccccattggcgc	CRISPR spacer
gtcgtcgtcgaggaggtccccgtcggcgg	Protospacer
 ..******************.*.**** 

72. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NC_011368 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence) position: , mismatch: 6, identity: 0.812

gctcggt--ggcggcgcgtgccgctttgccggca	CRISPR spacer
--tcggctgggcggcgcgttccgccttgccggcg	Protospacer
  ****.  ********** ****.********.

73. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 6, identity: 0.812

gctcggtg---gcggcgcgtgccgctttgccggca	CRISPR spacer
---cggtggacgcggcgcgggccggtttgccggcg	Protospacer
   *****   ******** **** *********.

74. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 6, identity: 0.812

gctcggtg---gcggcgcgtgccgctttgccggca	CRISPR spacer
---cggtggacgcggcgcgggccggtttgccggcg	Protospacer
   *****   ******** **** *********.

75. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to CP053333 (Salmonella enterica subsp. diarizonae serovar 47:k:z35 strain 2009K1094 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

gctcggtggcggcgcgtgccgctttgccggca-	CRISPR spacer
catcgatggcggcgcgggccgcttt-caggcag	Protospacer
  ***.********** ******** * **** 

76. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP016620 (Microvirga ossetica strain V5/3m plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.812

-gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
cgcatggt-gcggcgcgtgccgccttgtcggcg	Protospacer
 ** .*** **************.***.****.

77. spacer 14.1|4150342|27|NC_017093|CRISPRCasFinder matches to NZ_CP053710 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

tgtcaccgacgacgggaaggcttgctt	CRISPR spacer
cgataccgacgacggtaaggcttgccg	Protospacer
.* .*********** *********. 

78. spacer 14.1|4150342|27|NC_017093|CRISPRCasFinder matches to LN997845 (Streptomyces reticuli genome assembly TUE45, plasmid : IV) position: , mismatch: 6, identity: 0.778

tgtcaccgacgacgggaaggcttgctt	CRISPR spacer
cttcgccgacgacgggaaggcttacga	Protospacer
. **.******************.*  

79. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP050107 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b1, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
cacccaccgcggtcgcggtcgccctgg	Protospacer
.* ******************** . .

80. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP050112 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b5, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
cacccaccgcggtcgcggtcgccctgg	Protospacer
.* ******************** . .

81. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP010990 (Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
ccgccaccgcggtcgaggtcgcccacg	Protospacer
. ************* *******  *.

82. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP010990 (Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
ccgccaccgcggtcgaggtcgcccacg	Protospacer
. ************* *******  *.

83. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP012185 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
ccgccaccgcggtcgaggtcgcccacg	Protospacer
. ************* *******  *.

84. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP012185 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
ccgccaccgcggtcgaggtcgcccacg	Protospacer
. ************* *******  *.

85. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP012185 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
ccgccaccgcggtcgaggtcgcccacg	Protospacer
. ************* *******  *.

86. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP012185 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
ccgccaccgcggtcgaggtcgcccacg	Protospacer
. ************* *******  *.

87. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP012186 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
ccgccaccgcggtcgaggtcgcccacg	Protospacer
. ************* *******  *.

88. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
tcgccaacgcggtcgcggtcgccggtc	Protospacer
* **** ****************. . 

89. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP012182 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
ccgccaccgcggtcgaggtcgcccacg	Protospacer
. ************* *******  *.

90. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP012182 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
ccgccaccgcggtcgaggtcgcccacg	Protospacer
. ************* *******  *.

91. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP012182 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
ccgccaccgcggtcgaggtcgcccacg	Protospacer
. ************* *******  *.

92. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP012182 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
ccgccaccgcggtcgaggtcgcccacg	Protospacer
. ************* *******  *.

93. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP012182 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
ccgccaccgcggtcgaggtcgcccacg	Protospacer
. ************* *******  *.

94. spacer 20.3|6561113|27|NC_017093|CRT matches to MK411746 (Arthrobacter phage Sonali, complete genome) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
tggccaccgaggtcgcggtcgccgagg	Protospacer
*.******* *************.  .

95. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP013516 (Rhizobium sp. N1314 plasmid pRspN1314e, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
cgacgaccgccgtcgcggtcgccaccg	Protospacer
...* ***** ***************.

96. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP012183 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-2, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
ccgccaccgcggtcgaggtcgcccacg	Protospacer
. ************* *******  *.

97. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_LR594663 (Variovorax sp. RA8 plasmid 2) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
gcgccaccgcggccgccgtcgccacgg	Protospacer
  **********.*** ******** .

98. spacer 20.5|6561215|27|NC_017093|CRT matches to NC_023283 (Streptomyces sp. FR1 plasmid pFRL3, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtctccgcca	CRISPR spacer
cgaagaccacggtcgcggtctccgcca	Protospacer
...  ***.******************

99. spacer 20.5|6561215|27|NC_017093|CRT matches to NC_023284 (Streptomyces sp. F2 plasmid pFRL4, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtctccgcca	CRISPR spacer
cgaagaccacggtcgcggtctccgcca	Protospacer
...  ***.******************

100. spacer 20.5|6561215|27|NC_017093|CRT matches to NC_011961 (Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtctccgcca	CRISPR spacer
cagcgaccgcgatcgcggtctccggtc	Protospacer
.*** ******.************ . 

101. spacer 20.5|6561215|27|NC_017093|CRT matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtctccgcca	CRISPR spacer
cggccaccgccgtcccggtctccgcgg	Protospacer
..******** *** ********** .

102. spacer 20.5|6561215|27|NC_017093|CRT matches to NZ_CP018075 (Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtctccgcca	CRISPR spacer
aggccaccgccgccgcggtctccgcgc	Protospacer
 .******** *.************  

103. spacer 20.5|6561215|27|NC_017093|CRT matches to NZ_CP030829 (Neorhizobium sp. NCHU2750 plasmid pNCHU2750b, complete sequence) position: , mismatch: 6, identity: 0.778

tagccaccgcggtcgcggtctccgcca	CRISPR spacer
cggccaccgcgggcgccgtctccgctg	Protospacer
..********** *** ********..

104. spacer 20.6|6561260|30|NC_017093|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.8

ggacggtcaccctgcggacggtcgccacca	CRISPR spacer
ggcaggacaccctgcggacggtcgccgcgg	Protospacer
**  ** *******************.* .

105. spacer 20.6|6561260|30|NC_017093|CRT matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 6, identity: 0.8

ggacggtcaccctgcggacggtcgccacca	CRISPR spacer
ggacggtcgccctgcagacggtcgtgacgg	Protospacer
********.******.********. ** .

106. spacer 20.6|6561260|30|NC_017093|CRT matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 6, identity: 0.8

ggacggtcaccctgcggacggtcgccacca	CRISPR spacer
tgacggtcaccctgcagacgatcggctcga	Protospacer
 **************.****.*** * * *

107. spacer 20.6|6561260|30|NC_017093|CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 6, identity: 0.8

ggacggtcaccctgcggacggtcgccacca	CRISPR spacer
tgacggtcaccctgcagacgatcggctcga	Protospacer
 **************.****.*** * * *

108. spacer 20.10|6561488|27|NC_017093|CRT matches to NC_006462 (Thermus thermophilus HB8 plasmid pTT27, complete sequence) position: , mismatch: 6, identity: 0.778

ccgccaccctggtagccaccgcgatcg	CRISPR spacer
tcgccaccctggtcgccaccgccgagg	Protospacer
.************ ******** .  *

109. spacer 20.10|6561488|27|NC_017093|CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 6, identity: 0.778

ccgccaccctggtagccaccgcgatcg	CRISPR spacer
tcgccaccctggtcgccaccgccgagg	Protospacer
.************ ******** .  *

110. spacer 24.2|7049190|28|NC_017093|CRISPRCasFinder matches to NZ_CP037902 (Cupriavidus metallidurans strain BS1 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.786

agccaagacggccagcgcagccaagacg	CRISPR spacer
gaccaagaaggccatcgcagccaagccc	Protospacer
..****** ***** ********** * 

111. spacer 24.2|7049190|28|NC_017093|CRISPRCasFinder matches to LC473083 (Cutibacterium acnes TP-CU389 plasmid pTZC1 DNA, complete sequence) position: , mismatch: 6, identity: 0.786

agccaagacggccagcgcagccaagacg	CRISPR spacer
ggtgaagaccgccatcgcagccaagacc	Protospacer
.*. ***** **** ************ 

112. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 6, identity: 0.806

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cggcagcggcgacgaccggatcgccggcacc	Protospacer
**********.************.***..  

113. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 6, identity: 0.806

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cggcggcggcaacgaccggatcgtcatcggt	Protospacer
****.********************. .*. 

114. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 6, identity: 0.806

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cggcagcggcgacgaccggatcgccggcacc	Protospacer
**********.************.***..  

115. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP039899 (Agrobacterium tumefaciens strain CFBP5877 plasmid pAtCFBP5877a, complete sequence) position: , mismatch: 6, identity: 0.806

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cgagagcggccacgaccggatcttcggtggc	Protospacer
**. ****** *********** ******. 

116. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP039890 (Agrobacterium tumefaciens strain CFBP5499 plasmid pAtCFBP5499a, complete sequence) position: , mismatch: 6, identity: 0.806

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cgagagcggccacgaccggatcttcggtggc	Protospacer
**. ****** *********** ******. 

117. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP015094 (Pelagibaca abyssi strain JLT2014 plasmid pPABY6, complete sequence) position: , mismatch: 6, identity: 0.806

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
attggccggcaacgacagtctcgacggcggc	Protospacer
  .***************.******** **.

118. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP014802 (Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence) position: , mismatch: 6, identity: 0.806

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgatgacggcaacgacagcctctacggcggc	Protospacer
**  * **************** **** **.

119. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP018229 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.806

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
tggagccggcaacgacatcctcgacggcggc	Protospacer
.* .************* ********* **.

120. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP010865 (Marinovum algicola DG 898 plasmid pMaD10, complete sequence) position: , mismatch: 6, identity: 0.806

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cggcgccggcaacgacagcctctacggcagc	Protospacer
**  ****************** **** .*.

121. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP023976 (Streptomyces alboflavus strain MDJK44 plasmid pMDJK44.1, complete sequence) position: , mismatch: 6, identity: 0.806

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcctcgacagcctcgtccagggt	Protospacer
**********  *********** * ..***

122. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NC_016623 (Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence) position: , mismatch: 6, identity: 0.806

--cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
gccgcag--ggcaacgacagcctggacggtggc	Protospacer
  ***.*  ************** ***** **.

123. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP010598 (Phaeobacter inhibens strain P10 plasmid pP10_c, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
tggtgacggcaacgacaccctgtacggtgac	Protospacer
. ..******.********** *********

124. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NC_018288 (Phaeobacter inhibens DSM 17395 plasmid pPGA1_65, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
tggtgacggcaacgacaccctgtacggtgac	Protospacer
. ..******.********** *********

125. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP014802 (Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cagcgacggctacgacaccatctacggcggc	Protospacer
* .******* ******** *******.*.*

126. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP014802 (Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggcgacggcaacgacacgctctacggcggc	Protospacer
* .*******.******* ********.*.*

127. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP014802 (Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cagcgacggcaacgacagcctctacggcaac	Protospacer
* .*******.****** *********..**

128. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP014802 (Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cgatgacggcaacgacagcctctacggcggc	Protospacer
* *.******.****** *********.*.*

129. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP019311 (Phaeobacter inhibens strain DOK1-1 plasmid pDOK1-1-4, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
tggtgaaggcgacgacaccctgtacggtgac	Protospacer
. ..** ************** *********

130. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggcaacggcgacgacaccctcgacggcggc	Protospacer
* .*.***************** ****.*.*

131. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP030772 (Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggcatcggcgccgacaccatctacggtgac	Protospacer
* .*. ***** ******* ***********

132. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP013855 (Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctct--acggtgac	CRISPR spacer
gcacgtcggcgacgacaccctctccgcgatg--	Protospacer
 **** *****************  .**.**  

133. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
tgacgacggcgacgacacactcgacggcggc	Protospacer
. **************** *** ****.*.*

134. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
tgacgacggcgacgacacactcgacggcggc	Protospacer
. **************** *** ****.*.*

135. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
tgacgacggcgacgacacactcgacggcggc	Protospacer
. **************** *** ****.*.*

136. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
tgacgacggcgacgacacactcgacggcggc	Protospacer
. **************** *** ****.*.*

137. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cgatgacggcaacgacacgctctacggcggc	Protospacer
* *.******.******* ********.*.*

138. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cgaggacggcgacgacacactcgacggcggc	Protospacer
* * ************** *** ****.*.*

139. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cgaggacggcgacgacacactcgacggcggc	Protospacer
* * ************** *** ****.*.*

140. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 6, identity: 0.806

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cgatgacggcaacgacacgctctacggcggc	Protospacer
* *.******.******* ********.*.*

141. spacer 1.1|191082|31|NC_017093|CRISPRCasFinder matches to NZ_CP044073 (Pseudomonas oryzihabitans strain FDAARGOS_657 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.774

cgtgatggccctctaccaccagctctccgag	CRISPR spacer
ggtgatggccctctaccaaccgctgctcgat	Protospacer
 ***************** * *** ..*** 

142. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NC_020894 (Streptomyces hygroscopicus subsp. jinggangensis TL01 plasmid pSHJGH1, complete sequence) position: , mismatch: 7, identity: 0.788

gggtggatggccgcgctggcctacgg---ctggggg	CRISPR spacer
cggtagatggccgagctggcctacggggcctgc---	Protospacer
 ***.******** ************   ***    

143. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NC_017766 (Streptomyces hygroscopicus subsp. jinggangensis 5008 plasmid pSHJG1, complete sequence) position: , mismatch: 7, identity: 0.788

gggtggatggccgcgctggcctacgg---ctggggg	CRISPR spacer
cggtagatggccgagctggcctacggggcctgc---	Protospacer
 ***.******** ************   ***    

144. spacer 6.1|1745772|29|NC_017093|CRISPRCasFinder matches to NZ_CP022566 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK02, complete sequence) position: , mismatch: 7, identity: 0.759

cctgtcgtcgaggaggtccccattggcgc	CRISPR spacer
gctgtcgtcgaggaggtcgccaaggccca	Protospacer
 ***************** ***  * *  

145. spacer 8.1|2539069|33|NC_017093|CRISPRCasFinder matches to NZ_CP039644 (Azospirillum sp. TSA2s plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.788

tgctgagagcactggacaccggccggtccggct	CRISPR spacer
tgcggctggcgctgcacaccggccggtccggcg	Protospacer
*** *  .**.*** ***************** 

146. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP021372 (Rhizobium sp. ACO-34A plasmid pRACO34Ad, complete sequence) position: , mismatch: 7, identity: 0.781

gctcggtg-gcggcgcgtgccgctttgccggca	CRISPR spacer
-cacggaacgcggcgcgatccgctttgccggcc	Protospacer
 * *** . ********  ************* 

147. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.741

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
acgccaccggggtcgcggtcgccgaac	Protospacer
  ******* *************.   

148. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_CP024895 (Amycolatopsis sp. AA4 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.741

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
cgctgaccgcggtcgcggtcgcctccc	Protospacer
.. . ****************** ** 

149. spacer 20.3|6561113|27|NC_017093|CRT matches to NZ_LR134461 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 19, complete sequence) position: , mismatch: 7, identity: 0.741

tagccaccgcggtcgcggtcgccacca	CRISPR spacer
ccttcctcgcggtcgcggtcgccaccg	Protospacer
.  .* .*******************.

150. spacer 20.5|6561215|27|NC_017093|CRT matches to MN096378 (Microbacterium phage MCubed, complete genome) position: , mismatch: 7, identity: 0.741

tagccaccgcggtcgcggtctccgcca	CRISPR spacer
ccaagaccgctgtcgcggtctccgccg	Protospacer
. .  ***** ***************.

151. spacer 20.5|6561215|27|NC_017093|CRT matches to MH513982 (Microbacterium phage Sansa, complete genome) position: , mismatch: 7, identity: 0.741

tagccaccgcggtcgcggtctccgcca	CRISPR spacer
ccaagaccgctgtcgcggtctccgccg	Protospacer
. .  ***** ***************.

152. spacer 20.6|6561260|30|NC_017093|CRT matches to CP000666 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA05, complete sequence) position: , mismatch: 7, identity: 0.767

ggacggtcaccctgcggacggtcgccacca	CRISPR spacer
gatagatcaccctgcgggcggtcgccacgc	Protospacer
*.  *.***********.**********  

153. spacer 20.6|6561260|30|NC_017093|CRT matches to NZ_CP011665 (Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence) position: , mismatch: 7, identity: 0.767

ggacggtcaccctgcggacggtcgccacca	CRISPR spacer
tgacggtcaccatgcggacggccggatccg	Protospacer
 ********** *********.**   **.

154. spacer 20.6|6561260|30|NC_017093|CRT matches to NZ_CP024308 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3a, complete sequence) position: , mismatch: 7, identity: 0.767

ggacggtcaccctgcggacggtcgccacca	CRISPR spacer
aaacggtgaccctccggacggtcgcggccg	Protospacer
..***** ***** *********** .**.

155. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP015006 (Aminobacter aminovorans strain KCTC 2477 plasmid pAA01, complete sequence) position: , mismatch: 7, identity: 0.774

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
gcgcagctgcaacgtccggatcgtcggcgtc	Protospacer
  ***** ****** ************.*  

156. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NC_020548 (Azoarcus sp. KH32C plasmid pAZKH, complete sequence) position: , mismatch: 7, identity: 0.774

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cgacagcggcaacaaccggatcgtcacggct	Protospacer
**.**********.***********.  *  

157. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP024310 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence) position: , mismatch: 7, identity: 0.774

cggcag--cggcaacgaccggatcgtcggtgag	CRISPR spacer
--gccgttcggcaacgaccagatcgtcggtcgt	Protospacer
  ** *  ***********.********** . 

158. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP023064 (Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence) position: , mismatch: 7, identity: 0.774

cggcag--cggcaacgaccggatcgtcggtgag	CRISPR spacer
--gccgttcggcaacgaccagatcgtcggtcgt	Protospacer
  ** *  ***********.********** . 

159. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cggcagcggcaacgacacgatcggccttggc	Protospacer
****************  ***** *  **. 

160. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cggcagcggcaacgacacgatcggccttggc	Protospacer
****************  ***** *  **. 

161. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.774

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cggcagcggcaacgacacgatcggccttggc	Protospacer
****************  ***** *  **. 

162. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cggcagcggcaacgacacgatcggccttggc	Protospacer
****************  ***** *  **. 

163. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cggcagcggcaacgacacgatcggccttggc	Protospacer
****************  ***** *  **. 

164. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.774

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cggcagcggcaacgacacgatcggccttggc	Protospacer
****************  ***** *  **. 

165. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cggcagcggcaacgacacgatcggccttggc	Protospacer
****************  ***** *  **. 

166. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

cggcagcggcaacgaccggatcgtcggtgag-----	CRISPR spacer
cggcagccgcaacgacccgatcg-----gaggattc	Protospacer
******* ********* *****     ***     

167. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP019319 (Tateyamaria omphalii strain DOK1-4 plasmid pDOK1-4-7, complete sequence) position: , mismatch: 7, identity: 0.774

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cggcagcggcaatgaccggctcgagggcggt	Protospacer
************.****** ***  **.*. 

168. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
ctataccggcaacgacagcctggacggcggg	Protospacer
*   .**************** ***** ** 

169. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP014802 (Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgaaagcggcaacgacagcctctacggcggc	Protospacer
** .. **************** **** **.

170. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP054022 (Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcgggcggcatcgacagcctcgaggccgcg	Protospacer
***** ***** ************ *  *  

171. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP054022 (Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgaaggtggcaacgacaggctcgacggcgga	Protospacer
** .* .*********** ******** ** 

172. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP054032 (Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgaaggtggcaacgacaggctcgacggcgga	Protospacer
** .* .*********** ******** ** 

173. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP032341 (Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cggccgcggcaacgacatcctcgacggcggc	Protospacer
**    *********** ********* **.

174. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP014598 (Yangia sp. CCB-MM3 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
caggagcggcaacgacagtctcgacggcggg	Protospacer
*. *. ************.******** ** 

175. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP014598 (Yangia sp. CCB-MM3 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
caggagcggcaacgacagtctcgacggcggg	Protospacer
*. *. ************.******** ** 

176. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cggccgcggcaacgacatcctcgacggcggc	Protospacer
**    *********** ********* **.

177. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP033315 (Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cggccgcggcaacgacatcctcgacggcggc	Protospacer
**    *********** ********* **.

178. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cggtctgggcaacgacagcctggacggcggt	Protospacer
**   . ************** ***** ***

179. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cggccgcggcaacgacatcctcgacggcggc	Protospacer
**    *********** ********* **.

180. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP029831 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
gccgcaaggcaacgacagcctggacggcggt	Protospacer
  **   ************** ***** ***

181. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
ctcggccggcgacgacggcctcgacgagcct	Protospacer
* ********.*****.*********..  *

182. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP012916 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cggccgcggcaacgacatcctcgacggcggc	Protospacer
**    *********** ********* **.

183. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cggcgccgccaccgacagcctcgacggtgtc	Protospacer
**  **** ** *************** * .

184. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP017947 (Bosea sp. Tri-49 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgggaaggggaacgacaggctcgacggagga	Protospacer
** *.  ** ******** *********** 

185. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 7, identity: 0.774

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cggcacgggcaacgacagcctggacggtggg	Protospacer
**  .* ************** ***** ** 

186. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NC_013857 (Azospirillum sp. B510 plasmid pAB510c, complete sequence) position: , mismatch: 7, identity: 0.774

cgcggcc----ggcaacgacagcctcgacggaggt	CRISPR spacer
----gcccaagggcaacgacagcctggacggtggc	Protospacer
    ***    ************** ***** **.

187. spacer 25.3|8477978|31|NC_017093|CRISPRCasFinder matches to NC_016585 (Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence) position: , mismatch: 7, identity: 0.774

aaaccagggccatgacaaggtgtggggcggc-	CRISPR spacer
tgtgcagggccatgacaaggtct-gggtggcg	Protospacer
 .  ***************** * ***.*** 

188. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP010678 (Phaeobacter gallaeciensis strain P75 plasmid pP75_e, complete sequence) position: , mismatch: 7, identity: 0.774

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggtgacggcgacgacaccctgttcggtggt	Protospacer
* ..***************** * *****..

189. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 7, identity: 0.774

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
tgaagacggcgacgacgcgctctacggcggc	Protospacer
. * ************.* ********.*.*

190. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP016368 (Phaeobacter porticola strain P97 plasmid pP97_d, complete sequence) position: , mismatch: 7, identity: 0.774

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
tggtgacggcgacgacaacctcgacggtggc	Protospacer
. ..************* **** ******.*

191. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP010642 (Phaeobacter gallaeciensis strain P73 plasmid pP73_f, complete sequence) position: , mismatch: 7, identity: 0.774

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggtgacggcgacgacaccctgttcggtggt	Protospacer
* ..***************** * *****..

192. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP029359 (Azospirillum sp. CFH 70021 plasmid unnamed4) position: , mismatch: 7, identity: 0.774

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggcgacggcgacgacaccctcatcggcaat	Protospacer
* .*******************  ***..*.

193. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.774

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggcgacggcgacgacacgctcaacggcggg	Protospacer
* .*************** *** ****.*. 

194. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.774

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggcgacggcgacgacacgctcaacggcggg	Protospacer
* .*************** *** ****.*. 

195. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP033315 (Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.774

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggcgacggcgacgacacgctcaacggcggg	Protospacer
* .*************** *** ****.*. 

196. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to ASHF01000034 (Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence) position: , mismatch: 7, identity: 0.774

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
ctccatcggcgacgacaccctctggggtgtc	Protospacer
*. *. *****************. **** *

197. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to MK977704 (Gordonia Terrae phage RoadKill, complete genome) position: , mismatch: 7, identity: 0.774

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
caccgacgccgacgacaccctcgacgccgag	Protospacer
*  ***** ************* *** .** 

198. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to MT498054 (Gordonia Phage Engineer, complete genome) position: , mismatch: 8, identity: 0.758

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
gggtcgatggccgcgctggcctacatcggactc	Protospacer
**** *******************. * *.   

199. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to MK376959 (Gordonia phage Aphelion, complete genome) position: , mismatch: 8, identity: 0.758

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
gggtcgatggccgcgctggcctacatcggactc	Protospacer
**** *******************. * *.   

200. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to KU998244 (Gordonia phage Smoothie, complete genome) position: , mismatch: 8, identity: 0.758

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
gggtcgatggccgcgctggcctacatcggactc	Protospacer
**** *******************. * *.   

201. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to KU998247 (Gordonia phage Bachita, complete genome) position: , mismatch: 8, identity: 0.758

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
gggtcgatggccgcgctggcctacatcggactc	Protospacer
**** *******************. * *.   

202. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to MF919520 (Gordonia phage Lozinak, complete genome) position: , mismatch: 8, identity: 0.758

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
gggtcgatggccgcgctggcctacatcggactc	Protospacer
**** *******************. * *.   

203. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 8, identity: 0.75

gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
tccggaagacggcgtgggccgctttgccggca	Protospacer
 *. *. *.*****.* ***************

204. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
tccggaagacggcgtgggccgctttgccggca	Protospacer
 *. *. *.*****.* ***************

205. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
tccggaagacggcgtgggccgctttgccggca	Protospacer
 *. *. *.*****.* ***************

206. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 8, identity: 0.75

gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
gctcggtggcggcgtgtcccgctcgctctgcc	Protospacer
**************.** *****.  .* ** 

207. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 8, identity: 0.75

gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
tccggaagacggcgtgggccgctttgccggca	Protospacer
 *. *. *.*****.* ***************

208. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
tccggaagacggcgtgggccgctttgccggca	Protospacer
 *. *. *.*****.* ***************

209. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
tccggaagacggcgtgggccgctttgccggca	Protospacer
 *. *. *.*****.* ***************

210. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP032695 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence) position: , mismatch: 8, identity: 0.75

gctcggtg-gcggcgcgtgccgctttgccggca	CRISPR spacer
-cctgatatgcggcgcgggccgccttgccggcg	Protospacer
 *..*.*. ******** *****.********.

211. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
tccggaagacggcgtgggccgctttgccggca	Protospacer
 *. *. *.*****.* ***************

212. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
tccggaagacggcgtgggccgctttgccggca	Protospacer
 *. *. *.*****.* ***************

213. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
tccggaagacggcgtgggccgctttgccggca	Protospacer
 *. *. *.*****.* ***************

214. spacer 13.2|4002963|29|NC_017093|CRISPRCasFinder matches to LR026998 (unidentified phage genome assembly, chromosome: 1) position: , mismatch: 8, identity: 0.724

gcgactcaacccgtcaacgcgactcgaca	CRISPR spacer
atacttcaacccgtcaacacgacacgacc	Protospacer
... .*************.**** **** 

215. spacer 13.2|4002963|29|NC_017093|CRISPRCasFinder matches to NC_048666 (Salmonella phage YSD1 strain YSD1_PHAGE genome assembly) position: , mismatch: 8, identity: 0.724

gcgactcaacccgtcaacgcgactcgaca	CRISPR spacer
atacttcaacccgtcaacacgacacgacc	Protospacer
... .*************.**** **** 

216. spacer 20.6|6561260|30|NC_017093|CRT matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 8, identity: 0.733

ggacggtcaccctgcggacggtcgccacca	CRISPR spacer
cccccttcatcctgcggccggtcgccaccg	Protospacer
   *  ***.******* ***********.

217. spacer 20.6|6561260|30|NC_017093|CRT matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

ggacggtcaccctgcggacggtcgccacca	CRISPR spacer
cccccttcatcctgcggccggtcgccaccg	Protospacer
   *  ***.******* ***********.

218. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 8, identity: 0.742

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
caacagcggctacgaccggatcgtcgaaaga	Protospacer
*..******* ***************. ...

219. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 8, identity: 0.742

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
caacaccggctacgaccggatcgtcgggcga	Protospacer
*..** **** ****************  ..

220. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 8, identity: 0.742

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cggcatcggcaacgacaggatcgcggtcggt	Protospacer
***** ********** ******. * .*. 

221. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 8, identity: 0.742

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cgaagccggcaacgacacgatcgtcggtggc	Protospacer
**. . **********  ***********. 

222. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 8, identity: 0.742

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cgcgagcgccatcgaccggatcgtcgggctc	Protospacer
**  **** ** ***************    

223. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP018096 (Chelatococcus daeguensis strain TAD1 plasmid pTAD1, complete sequence) position: , mismatch: 8, identity: 0.742

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cgcgagcgccatcgaccggatcgtcgggctc	Protospacer
**  **** ** ***************    

224. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP026305 (Streptomyces lunaelactis strain MM109 plasmid pSLUN1, complete sequence) position: , mismatch: 8, identity: 0.742

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cggcggcggcaaagaccggatcgaggacgct	Protospacer
****.******* **********  *..*  

225. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP014802 (Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence) position: , mismatch: 8, identity: 0.742

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cagctacggcaacgacagcgtcgacggcggg	Protospacer
*.    ************* ******* ** 

226. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP054022 (Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence) position: , mismatch: 8, identity: 0.742

-cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
gcacaa-gggcaccgacagcctcgacggcggc	Protospacer
 *.*..  **** *************** **.

227. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP054032 (Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence) position: , mismatch: 8, identity: 0.742

-cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
gcacaa-gggcaccgacagcctcgacggcggc	Protospacer
 *.*..  **** *************** **.

228. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NC_007949 (Polaromonas sp. JS666 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.742

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
ccgagccggcaacgacaccatcgacggtcgg	Protospacer
*  .************* * *******  * 

229. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.742

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
tggccgcggcaacgacatcctcgacggcggc	Protospacer
.*    *********** ********* **.

230. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to JQ807251 (Environmental Halophage eHP-32, partial genome) position: , mismatch: 8, identity: 0.742

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcggcctcgatgcgacc	Protospacer
************** *.*******.* .. .

231. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP014802 (Salipiger profundus strain JLT2016 plasmid pTPRO6, complete sequence) position: , mismatch: 8, identity: 0.742

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
tggcaacggcgacgacaccatctacggcggt	Protospacer
. .*.************** *******.*..

232. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP036297 (Planctomycetes bacterium Pla86 plasmid pPla86_1, complete sequence) position: , mismatch: 8, identity: 0.742

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
gttcgacggcgacgacaccctcttcggcctg	Protospacer
 . ******************** ***.   

233. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP036288 (Planctomycetes bacterium Pla133 plasmid pPla133_1, complete sequence) position: , mismatch: 8, identity: 0.742

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
gttcgacggcgacgacaccctcttcggcctg	Protospacer
 . ******************** ***.   

234. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NC_014502 (Gloeothece verrucosa PCC 7822 plasmid Cy782203, complete sequence) position: , mismatch: 8, identity: 0.742

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggtagcggtgacgacaccctctacggagag	Protospacer
* ....***.***************** ** 

235. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 8, identity: 0.742

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
aggcaatggcgacgacaccatcttcggtgat	Protospacer
  .*.*.************ *** ******.

236. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP017244 (Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence) position: , mismatch: 8, identity: 0.742

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cggtgaaggcgacgacacgctctacggaggg	Protospacer
* ..** *********** ******** *. 

237. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to KX241618 (Xanthomonas phage Xoo-sp2, complete genome) position: , mismatch: 8, identity: 0.742

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
gtccgacggcaacgacaccctgtacgcgggc	Protospacer
 . *******.********** ****  *.*

238. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to KX557276 (Gordonia phage Cucurbita, complete genome) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
gggtcgatggccgcgctggcctacatcgaactc	Protospacer
**** *******************. * ..   

239. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

240. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

241. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

242. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

243. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

244. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

245. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

246. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

247. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

248. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

249. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

250. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

251. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

252. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

253. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

254. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

255. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

256. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

257. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

258. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

259. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

260. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

261. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

262. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

263. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

264. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

265. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

266. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

267. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

268. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

269. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

270. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

271. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

272. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

273. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

274. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

275. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

276. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

277. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

278. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

279. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

280. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

281. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

282. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

283. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

284. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

285. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

286. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

287. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

288. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

289. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

290. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

291. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

292. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

293. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

294. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

295. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

296. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

297. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

298. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

299. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

300. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

301. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

302. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

303. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

304. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

305. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

306. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

307. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

308. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

309. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

310. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

311. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

312. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

313. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

314. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggagatggcggcgctgggctacggctggacc	Protospacer
  * .****** ******* **********.  

315. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NC_030901 (Gordonia phage ClubL, complete genome) position: , mismatch: 9, identity: 0.727

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ggctcgatggccgcgctggcctacatcggactc	Protospacer
** * *******************. * *.   

316. spacer 8.1|2539069|33|NC_017093|CRISPRCasFinder matches to NC_020894 (Streptomyces hygroscopicus subsp. jinggangensis TL01 plasmid pSHJGH1, complete sequence) position: , mismatch: 9, identity: 0.727

tgctgagagcactggacaccggccggtccggct	CRISPR spacer
tgtacgaggcactggacaccgtccgctccggcc	Protospacer
**.  ...************* *** ******.

317. spacer 8.1|2539069|33|NC_017093|CRISPRCasFinder matches to NC_017766 (Streptomyces hygroscopicus subsp. jinggangensis 5008 plasmid pSHJG1, complete sequence) position: , mismatch: 9, identity: 0.727

tgctgagagcactggacaccggccggtccggct	CRISPR spacer
tgtacgaggcactggacaccgtccgctccggcc	Protospacer
**.  ...************* *** ******.

318. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
tgcggaagacggcgtgggccgctttgccggca	Protospacer
  . *. *.*****.* ***************

319. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
tgcggaagacggcgtgggccgctttgccggca	Protospacer
  . *. *.*****.* ***************

320. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
tgcggaagacggcgtgggccgctttgccggca	Protospacer
  . *. *.*****.* ***************

321. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
tgcggaagacggcgtgggccgctttgccggca	Protospacer
  . *. *.*****.* ***************

322. spacer 16.1|4496518|37|NC_017093|CRISPRCasFinder matches to NC_011368 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence) position: , mismatch: 9, identity: 0.757

cgtgagctcgctcgtgttgtcggctgcggcgtgggcg	CRISPR spacer
cctcgtcacgctcgttttgtcggttgcggcgtgggtc	Protospacer
* * . * ******* *******.***********. 

323. spacer 20.6|6561260|30|NC_017093|CRT matches to NZ_CP042268 (Pseudomonas aeruginosa strain HOU1 plasmid pHOU1-1, complete sequence) position: , mismatch: 9, identity: 0.7

ggacggtcaccctgcggacggtcgccacca	CRISPR spacer
cgttcgtccccctgcggacggtcgcctttt	Protospacer
 * . *** ***************** .. 

324. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
cggcatcggcaacgacctgatcgacatccgc	Protospacer
***** *********** ***** *. . . 

325. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP013526 (Rhizobium phaseoli strain R744 plasmid pRphaR744d, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
gaatttcggcaaaaaccggatcgtcggtgac	Protospacer
 ...  ****** .**************** 

326. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP013556 (Rhizobium phaseoli strain N931 plasmid pRphaN931d, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
gaatttcggcaaaaaccggatcgtcggtgac	Protospacer
 ...  ****** .**************** 

327. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP013589 (Rhizobium phaseoli strain N161 plasmid pRphaN161d, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
gaatttcggcaaaaaccggatcgtcggtgac	Protospacer
 ...  ****** .**************** 

328. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP013562 (Rhizobium phaseoli strain N841 plasmid pRphaN841e, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
gaatttcggcaaaaaccggatcgtcggtgac	Protospacer
 ...  ****** .**************** 

329. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP013579 (Rhizobium phaseoli strain N671 plasmid pRphaN671e, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
gaatttcggcaaaaaccggatcgtcggtgac	Protospacer
 ...  ****** .**************** 

330. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP013531 (Rhizobium phaseoli strain R723 plasmid pRphaR723d, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
gaatttcggcaaaaaccggatcgtcggtgac	Protospacer
 ...  ****** .**************** 

331. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP013536 (Rhizobium phaseoli strain R650 plasmid pRphaR650d, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
gaatttcggcaaaaaccggatcgtcggtgac	Protospacer
 ...  ****** .**************** 

332. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NC_011368 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
gaatttcggcaaaaaccggatcgtcggtgac	Protospacer
 ...  ****** .**************** 

333. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP013541 (Rhizobium phaseoli strain R630 plasmid pRphaR630d, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
gaatttcggcaaaaaccggatcgtcggtgac	Protospacer
 ...  ****** .**************** 

334. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP013546 (Rhizobium phaseoli strain R620 plasmid pRphaR620d, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
gaatttcggcaaaaaccggatcgtcggtgac	Protospacer
 ...  ****** .**************** 

335. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP013567 (Rhizobium phaseoli strain N831 plasmid pRphaN831d, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
gaatttcggcaaaaaccggatcgtcggtgac	Protospacer
 ...  ****** .**************** 

336. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP013584 (Rhizobium phaseoli strain N261 plasmid pRphaN261d, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
gaatttcggcaaaaaccggatcgtcggtgac	Protospacer
 ...  ****** .**************** 

337. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP013573 (Rhizobium phaseoli strain N771 plasmid pRphaN771e, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
gaatttcggcaaaaaccggatcgtcggtgac	Protospacer
 ...  ****** .**************** 

338. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NZ_CP020900 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5d, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
gaatttcggcaaaaaccggatcgtcggtgac	Protospacer
 ...  ****** .**************** 

339. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
caacagcggctacgaccggaccgtcgaaaga	Protospacer
*..******* *********.*****. ...

340. spacer 25.1|8477870|31|NC_017093|CRISPRCasFinder matches to CP007643 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803b, complete sequence) position: , mismatch: 9, identity: 0.71

cggcagcggcaacgaccggatcgtcggtgag	CRISPR spacer
ctccagcggcaacgacaagatcgtcgacccc	Protospacer
*  ************* .********..   

341. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP050098 (Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b4, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
gtcggtcggcatcgacagcctcgaccaggtg	Protospacer
  ***.***** ************* ..*  

342. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

343. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

344. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

345. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

346. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

347. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

348. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

349. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

350. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

351. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

352. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

353. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

354. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP053209 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1A, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
gtcggtcggcatcgacagcctcgaccaggtg	Protospacer
  ***.***** ************* ..*  

355. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

356. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

357. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

358. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

359. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

360. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

361. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

362. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

363. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

364. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

365. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP050084 (Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b2, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
gtcggtcggcatcgacagcctcgaccaggtg	Protospacer
  ***.***** ************* ..*  

366. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP022220 (Bradyrhizobium guangxiense strain CCBAU 53363 plasmid p53363, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
ccgcttgggcaacgccggcctcgacggagga	Protospacer
*    . ******* *.************* 

367. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

368. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

369. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP031166 (Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
gaaggccggcagcgacaccctcgacgtcgcc	Protospacer
 . ********.***** ********  * .

370. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

371. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP030052 (Bradyrhizobium guangdongense strain CCBAU 51649 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
ccgcttgggcaacgccggcctcgacggagga	Protospacer
*    . ******* *.************* 

372. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccggcaacgtcagccccgccacctcg	Protospacer
************** *****.** *.     

373. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to NZ_CP030054 (Bradyrhizobium guangzhouense strain CCBAU 51670 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
ccgcttgggcaacgccggcctcgacggagga	Protospacer
*    . ******* *.************* 

374. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to MT684599 (Gordonia Phage Sephiroth, complete genome) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccgacaacgacagccccggtctcctt	Protospacer
********.***********.**..     *

375. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to MH976515 (Gordonia phage Octobien14, complete genome) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
cgcggccgacaacgacagccccggtttcctt	Protospacer
********.***********.**..     *

376. spacer 25.2|8477924|31|NC_017093|CRISPRCasFinder matches to MH727561 (Mycobacterium phage Serendipitous, complete genome) position: , mismatch: 9, identity: 0.71

cgcggccggcaacgacagcctcgacggaggt	CRISPR spacer
tgaggacggcaacgacatcctcgacgctccg	Protospacer
.* ** *********** ********     

377. spacer 25.4|8478032|31|NC_017093|CRISPRCasFinder matches to NZ_CP048285 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248a, complete sequence) position: , mismatch: 9, identity: 0.71

ccacgacggcgacgacaccctctacggtgac	CRISPR spacer
cgggcgaggcaacgacaacctctacggtgag	Protospacer
* .  . ***.****** ************ 

378. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 10, identity: 0.697

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggaaatggcggcgctgggctacggctggacc	Protospacer
  * ..***** ******* **********.  

379. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggaaatggcggcgctgggctacggctggacc	Protospacer
  * ..***** ******* **********.  

380. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggaaatggcggcgctgggctacggctggacc	Protospacer
  * ..***** ******* **********.  

381. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggaaatggcggcgctgggctacggctggacc	Protospacer
  * ..***** ******* **********.  

382. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggaaatggcggcgctgggctacggctggacc	Protospacer
  * ..***** ******* **********.  

383. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggaaatggcggcgctgggctacggctggacc	Protospacer
  * ..***** ******* **********.  

384. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggaaatggcggcgctgggctacggctggacc	Protospacer
  * ..***** ******* **********.  

385. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggaaatggcggcgctgggctacggctggacc	Protospacer
  * ..***** ******* **********.  

386. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggaaatggcggcgctgggctacggctggacc	Protospacer
  * ..***** ******* **********.  

387. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.697

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggaaatggcggcgctgggctacggctggacc	Protospacer
  * ..***** ******* **********.  

388. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggaaatggcggcgctgggctacggctggacc	Protospacer
  * ..***** ******* **********.  

389. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggaaatggcggcgctgggctacggctggacc	Protospacer
  * ..***** ******* **********.  

390. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.697

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggaaatggcggcgctgggctacggctggacc	Protospacer
  * ..***** ******* **********.  

391. spacer 4.1|1298810|33|NC_017093|CRISPRCasFinder matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

gggtggatggccgcgctggcctacggctggggg	CRISPR spacer
ctggaaatggcggcgctgggctacggctggacc	Protospacer
  * ..***** ******* **********.  

392. spacer 9.1|3315030|34|NC_017093|CRISPRCasFinder matches to NZ_CP033323 (Azospirillum brasilense strain Cd plasmid p5, complete sequence) position: , mismatch: 10, identity: 0.706

ctcagccgcgtggtgtcagcggaaggccgccttc	CRISPR spacer
ggtggagacatggtggaagcggaaggccgccttc	Protospacer
  ..*  .*.*****  *****************

393. spacer 9.1|3315030|34|NC_017093|CRISPRCasFinder matches to NZ_CP012919 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p5, complete sequence) position: , mismatch: 10, identity: 0.706

ctcagccgcgtggtgtcagcggaaggccgccttc	CRISPR spacer
ggtggagacatggtggaagcggaaggccgccttc	Protospacer
  ..*  .*.*****  *****************

394. spacer 9.1|3315030|34|NC_017093|CRISPRCasFinder matches to NZ_CP032344 (Azospirillum brasilense strain MTCC4038 plasmid p5, complete sequence) position: , mismatch: 10, identity: 0.706

ctcagccgcgtggtgtcagcggaaggccgccttc	CRISPR spacer
ggtggagacatggtggaagcggaaggccgccttc	Protospacer
  ..*  .*.*****  *****************

395. spacer 9.1|3315030|34|NC_017093|CRISPRCasFinder matches to NZ_CP033317 (Azospirillum brasilense strain Sp 7 plasmid p5, complete sequence) position: , mismatch: 10, identity: 0.706

ctcagccgcgtggtgtcagcggaaggccgccttc	CRISPR spacer
ggtggagacatggtggaagcggaaggccgccttc	Protospacer
  ..*  .*.*****  *****************

396. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to CP036421 (Rhodobacter sphaeroides strain HJ plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
cccgcccggcggcacgggccgctttgccggag	Protospacer
 *.   .******.** ************* .

397. spacer 11.1|3853064|32|NC_017093|CRISPRCasFinder matches to NZ_CP014600 (Yangia sp. CCB-MM3 plasmid unnamed4, complete sequence) position: , mismatch: 11, identity: 0.656

gctcggtggcggcgcgtgccgctttgccggca	CRISPR spacer
tgtcggtggcggcgcgggccgccttcttcatc	Protospacer
  ************** *****.** .. .. 

398. spacer 20.5|6561215|27|NC_017093|CRT matches to NZ_CP039912 (Agrobacterium tumefaciens strain CFBP6625 plasmid pAtCFBP6625a, complete sequence) position: , mismatch: 13, identity: 0.519

---------tagccaccgcggtcgcggtctccgcca	CRISPR spacer
attcggagaccgccaccgcggtcgctt---------	Protospacer
         . **************           

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	256658 : 289350	44	Streptomyces_phage(66.67%)	holin,capsid,tail,integrase,terminase	attL 287562:287577|attR 290640:290655
DBSCAN-SWA_2	8524219 : 8531768	10	Streptomyces_phage(33.33%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_017093|256658:289350|DBSCAN-SWA
ATCAGCGGTCGGCCGTGGCGCTGGTCGGCAGCAGGCTCGGGTCCGTGCTGTCGCCGACCGTGGTGCTCACGATCGACGTCAGCACCGACAGCACCGCGGCGCCACCCGCGATACCGGCCGCCCCGAGCGGGTCGACGTCGAACAGGTTGAAGGCGTCGCCGCCCCAGAGCAGCAGGAGCGCCTGGGCGGAAGACTTGACCGCGCGCTCACCGGTAGCCAGCCAGAACACTTTCTTGAACATCGATGCTCCCAACTTTGTCGTACACGTGTTCGATAATCAGGGGATGGGCATGCAGAACGGCACCTTGGACCAGGCGACGAACAGATGGATTCAGGACGAAGCGGATAAGCACTACAACGGGGATTGGGGCCGTGCGGCAGCAGCCATCCTGGAAGCGGCACACGCCCGAGCAGCTCACCCAGAAGACCAGTGGGCGGAGCTCGACTCGCGGGTCAAGAGCCGCGCGAAGTAGGTCAGCCGCACGTCTCCTGCGGTGACGGGGGTACCGGGTTCAGGCGGCGCTGCTCGTCCGCCTGGGCCCGGGCCATGTTGTACCGGCGGATCTCCGACAGCGCAGCGTCCGGCTGATCAGCAACCACCCGGAGCAGCTCGTCGAGCGCCTGGCGGTCCGCCTCCGCCGCCTCCGCCCGCGCCCGGGTGCTCGAGTTCGCCGACTCGTTGTACCGGGCCTGGCACGAGGTCATCTGGACCTGCCGAACGCCGATCATCACCGACAGGAGCAGGGCAACGGCCGCCATCAGACGCCAGGCGATGTCGGCAGGCCGCGAAGTCAGCCAGCGTGCAACGGCTGTGGTCATCGGTCGTGGTCTCCTCGGTCTCGGGTAGCCCGCCGCCAGATCAGCGGTCGAGCAGCGAGACCGAGGGCCCCGCACGTAACGATGGACAGGGCGGCCTGGAGTCCGTACAGCATGGTCACGTCTGTGCCCCGTCCCGAGGCTCGGCAGACGCACCGGGGGACGGGCTTTCGCTACCGCCTCCGCTGCGGCCGATCGCCGGCGGCGCGAGCGCGAGCACCAGGCCGGCCGGGACGCCCAGGAGGATCGCGTCGGGGAGCTGGCCGCGCACGAGTGAAACGATCACGACGGCGAGCCAGGCCCCGAGTCCGGTGATCATGGTCAGATTCCGGAGCCAGGCCGGCACGTGATCAGCCCCCGTTGGCCGCAGATGGATGGGTCAGGTGGTGCTACGCCGCGGCGAGACGCTCGCCGAGCGCGTCGACGACGTCCTGGGCGATGCCGTCCGGGATCCCCGCGGCGATCCGCTCCGGCGTGAGACCGGCCAGCACGGCGTCCACGATCGCGTCCTCGTCGACCAGGTCCTTGCCGCCGAGCGCGGCCACCTGCTTGGCGAGTGCGCCGATCGCGGCGAGGATGCGGGCCCGCTCGGGCGAGCCGTACGCGTCGACGTTGCTCCAGCGCTGCCAGTTCGGGGTCTTTCCCGTGCCGGGGTTGACGTTGACCTTCAGATCTCCGACCGCCTTGGCGAAGTCGGGCAGGGCGTCCTTGAGCTCGGCCTTGACCGCAGCCCTCAGCTGTTCCGGTGTCACGTCGTCCTCCTCTACGCCCCACGGGCGCGTATCGCTCTCGGTCCTGGTCAGATACCGCGCGCTGATGTGCGCGTGATCGAAGTGCTTGGACGCGCCGGAGTACGTGCGCCACTCGGACCAGCCCCACGAACGGGAGATGATCCGGCCGCGCCAGATGATGTACTGCAGCCGGCCGTAGACGTCCGGACTTGCGTACTCGATGCGTTCCTGGGCGGCGATGTGCTGAATCCGCCGGTCGAACCAGCCACCGGCTTCCCGGCCCGAACCGTCCGGCCACGGCCCATCACTGTCGACATCTACCGCGTGGACCTCGTTCTTGTCGTCTGCGTCGTGATCACGCAGAACGTCGGAGTCCTCGTCCGGGGTGTGATCCGACGACGAGGTATGCGACGAGTCACCGATCGCACCATCGGCGCCCTTGTCCCTGCGCGGGGCGACTGAGTTGAACTCGTCGCGCAGCTTGACCAGGCACGGCACCAGCATCCAGTCAGCCATATCGGCCCTCCGATCAGTAGGTAGGTGCGCCAGGGCAGTCGTCGTACGCGCCCGCTTGCCGGACCACCATCTCGAACGGACCGGAGGCGAAGCCTTTGAAGGCGGCCGTGCCGGCGCTGACGGTCCCACGGAACACGATCCCGACGGTCGCAGCCGTGAACGTCGGCGCGGTGCGGAAACTGCAGCGGAATTCATAGAAACGGGCGCCCGTGGCTGGGAGACCCTGGCGGCCGTAGTCGACGAGGATCGAGCTATCGGGCCGCCGGATCTGCGGGAGGAAATCGAGCGCGGCCGAGGTGGAGACCTGGGAGCGCACGGTCACGTCGTAGGCCCATCCGGGCCGCAGCGCGGTGGCTGCGGTGCAGATGGTCTGGCCTGCGGTTGTGACCGTTTGGACGGTGCCGGTGTTGCTGTAGTAGCCCACGACCCGCCCGACGTCCCGGATGGCTGCCTCAGCAGCCTCGGCGAGGGACTGGCTCAAGAGAGGGCCGTTGGGCGGATCGTCGTCCTCTTGATACGGCAGGCCGTAGATCGGGGTGCTGTCGACCATCGGGTGCTCCTCACAGGGCCATGGCGGTGATGTTGCGGTTTTCGAAGTTGGCCTGCACGGCACCGCCGCGCCGGCGGTACATCGCTGTGATGGTGGTGAGGCCTGGGGTTAGCCCTTCGAGCAGGACGAGCCGCCCTGCGGCGCCCGTCGTACCGAAGGTGACAGCGCTGGAGGAGACGAGGATGTTGCCGGACACGACATACGCACGAGAGGACGCTGCGCCGAGGGTGTTCGCTCCACTGAGCGCGAAACCCATATCGCCACCGGCAATGATCGTGTTCGCGGCAGCGGTTGTGCCCTGAGCTGAGATCTCTGCAGCAAGGAACACCATCAATCGCCCGCTCTTGCCCACGACGATGGAGACCACCGGTCCGCTGCCCGCCTTGAATGAGGTGCTGGTGAAGCTCTCCAGGCCGGTAACGGATGCCGACTGGGTGCGCAGCGAGGACAGCGCGGATACCGCCTCGGGACTGCCCGGGATCGTGAACCGGCCGAGGATGCCCCACGTGTTGCCCGAGACGAGGATGCTGACCACGTCGCCGATGTTCAGGATCGCCGCTTCGCTCGTGTTCAGGATCGACAGGTTCGCCATCACGGTTTCGTCGACGGCCACCAGGTTTTCGGCCGTCTCCTGGTTCCAGGACATCACCACGCCCTGGCGGAACTGGACGCCCGGCCCGGCGTCCGGCGGCCTCAGCAGCTCCACCAGCTCGTCGTCGGCCATCAGGTCTCTCCGATCGTGATCAGGGTTTGCTCCCGGGTGGTGGCCTGCATCGACTCGTCGACGGTGAGCGGGATGGTGAGGGTATCGATCACGTGCGTCTCCGTCTGGCCGCCGTCGACCTCGATCGCCACCGGGTCGTCTGGCTCGATCGCGGGGTTGACAATGGAGCGGAAGTCCACGTTGTACGGGAGCCCCAGCGCGCGTTTCAGGAGTGTCCGCGCGGCCGCCGTTGCGGCGGCGTTGCTGGTCAGCAGCGGGCTCGAAAACGTCCGGTGCACCCGCCCGAACGGCCCACCCCACCTCGTCGGTGACGTCGCGCCGGCATCGACAGCCAGACCGCGTGCTGGCGCGGTCGTGTCGAGGCCCTCGCCCTTGGCCAGGACGCCGTTATAGGTGCCGACCCGGGACAGGCTTCGGGAGGCCTCGACCAGCACGCCACCCTCGCCCTGAGCCACCGTCCACACCGGTGTGGCAGTGCTCGGCAGGTCGGAGATCTTCAAGACGCCGCGGTGGTCGAAATACCAGCGCTTCCCCAACCCGGTGATCAGCTCGTCGACGAATCCGTACCGGTCCTCCTCCACGGCCACGGTGCGACCGATCGGAGCGTTGGCCACCGTGGGCTCGTCCCACTCGATCACCGCAGCCGGGTACGCCTCGGTGACCAGCTGGGCCACCACGGACGCGTTGGTCCGGGCCGCCCCGAACTGCACAGGCGAGGTGAGCTTGCTGTCGACGATCGCGGCCATGCGGTCCACGGCCGTGACCTCTATCGGCCCGTTCGGCGGGACGTCCTGCTCGATGGTGTTGATTCGGTGGTAGCCCAGCGACACCCACTCCACCGCGCCGTTGCCGTAGGCGATCCCGCGCTCCACGAAAACTTCGTTGCCGTACGGGGTGAGCAGGTCCGACCCGTACTGGGGCCACAGCCCGGTGCCGTCGATCTCCAGGCTGAGCTGCGACCGGAGCGCCTGACCGGAGTCAAGGCGGACCTCGCCGTCGATGATCCGGACCTCGGTGCCGATCGGGGTGACTCCGGTCTGCCCGGGTGTGACGACCCAGGCCCGGACCACCGCGGTGTGCGATCCGGTGAGCGTCCGCAGGAACTTGTCGCTGACGGGTCTCACGGGACGATCACCGTCTCGGGATCTGCCACGTACGCGGCGACATCCGCCCATGTCGCGAACGTGGCAATAACGTCTGCCCAGGTGCCGAACTCGGCGAGCAGCGTGGCCCACGTGGCGGCAGCGCCGACCACGTCCGGGCCGGGCGCCGCCCGCTCCGACATGGGCAACGACCACACGCGCCGCCGATCACCCGGCAGCTGGGAGAGTCGGCGATGGCTGCTGGTGCCGACCTTCACGTATCCGGTCGGCACGTCACCGTCGTAGGTCGGCGGCACCTGCAGATAGAGCACATCGCCGAGTGCCAGCATCAGCTCCAGCGCGCGGGTATCGCCGGGGTCGTCGGTGCGGACCTCCAGCTCCCACTCGCGTGGACCGCGGACCTCGGCGACCTCCACGGGAAGGCTGCGGCCCTTAATCGCGAACGATCCCGAGCGGGTCGGCTGGCTAATCGCGGGCGCAGTCCGCACCGTCACGGCCCGGTTGAGGAACGGCCGGGCCACGCTTTTGAGCCACACCCGGTCGATCACTGCGGTGATGACGGCCGTCTCTGTGGAGACCAGCACGTTGCCGCTGGTGTAGCCACGCACGCGATAGGTGACCGGCTTCCCAGGCGGGAACTCGTAGTCGTCGAGAGCCACGGCGCCGGCGGCCGGGGCACGGCGGCCGCCGCCGCGCACGGTCGTCCACCGCCAGCCCGTGAGGCTACGGTCGATGACCGCGTATGCCACCGTGCCGACGACCGTGGCGGAGAGTCGTACGCGGGCCACCGCATCGTCGTAGGTGAGGGTGATCATCGACGCCTCCCCGTCGGCTGCGGCACCATCTTGGTCCGAGGACCTGCTTTCCTTGCCGTCTTGGCGTTCGACTTCTTGATCCGCACGTCGACGAGGTCCTCGATCTCTCGGGTGCCTAGGTAGACGTGCACCTCGATGGGCTGGCCGTTGCGGTCGGTGCCGTCCTGCCGGGCCTCGCGGACCAGGTTGTTGAGCTTGGACAGCGGCATGACCGCCTCGTCCTCGCGGCCTTCACCGACGATCGTGAGCCGGCCGCCGCGGGTCTTCGGGACCACGGCGCCTTTGGCGAGCATCGGAATGTTGGGCGTGTTGAGCGTGACGGACGGGATGCCCATGCCCAGGATCGATCCGCCGCCCAGCGTCAAGCTGAAGTTGTTCCACCGGCCGATCACCCAGTTGATCGCCGACCGGAACGCGGATTTCAGCCCGTCGAACGCGCCGCTGAGCGCGCTACGGAGCCGCCCTGGGAGCGCCTGGAACCAGTCGAGCGCCTGATTGCCCTTGTTGATGATCCCGTTCCAGGCACCCAAGATCCATTTCTGCCACAGGGTGTCCCGGAACCAGGAGCCCACCGCGCTCGCGGCCGATTTGATGCCGCCCCAGGCCGCTTTCCACATCTTCGAGAAGATGTCGGTCTGGCTGGCGATCAGTACGATGCCGGCCACCAGCGCGGCGATCGCGAGCACCACCAGGCCGATCGGGTTCATCGACAGCACCAGGTTCAGCGCGGTCTGCGCGATCGTCCAGAGCTTGACCACGCCGATGACCGTGCCGATGACCAGCGCGAGGGTGCCGAGAACCGCGGCGGCCGGCCCGACGACGGCAGAGTGCCGGTCGATCCAGCCCACCAGGGACTCGATGTACGGGATCGCCTGGCCGATCTTCTCCACCAGCGCGGCCTGCGCGCTCCGCTTGAACGACTCCAGGCGCTGGCTGGCGGACTGCTCCAGCGTCTCGCCCATCTTGTCCGCGGCACCGGACACGTCGCCCATCGACTTTGCGGCCGTGTCCAGGTCGAGCGCCAGCAGCGCACCGCCGAGGTTCTCACCGGGACCGCCGAAGAGGCCTTGGATGGCCTGCTGCGTGGTGGTGGATTCCGGGCCGAGCTCGCGCAGCTTGTCGAGCACCATCTGGAACGCGGCCTGCGCCTTCGGCCCGCCGGCGGCGATTCCGGAGGCCACGGTGTCGGCGTTCAGGCCGAGCGTGGCGAGGGCGTCGGAGGTGGTCTTGCTGCCGTCGACCGCGCGCAGCGAGAACTCTTTGACCGCGTCGGCGACGGAGTCCGCGTCACGGGCGCCGGCCTTCAGCCCCTGGGAGAGCAGGCCCGTGGCGGTTGTTCCGTCGATGCCCATCTTCTGGAACTGGACGGAGTACTCCGAGAACGTATCGAGCAGGTCGCCAGCGTGGTCACCGGTCTGCTGGAAACCGCGGGTGAGGATGTCGAACGCCTCGGCGCTGTCCTTGGCCAGGCCGGTGCGGACCATCTGGCCGGCGGCCCGGGCGGTCTGGGTCACGTCCTGCCCGAACGTATCGGCCAAGGCCTGCGCCTTGAGCGTGACGGACTCGATCTCAGCGTTCGTCGCGTCCTCGTCCAGCAAGCCGGACCCGAGGACACCACGCAGCGTCTCGTTGACCGCTTCCAGGGACTCGCCGAAACCCCTGCCGTAGACGTTTCCCGCGATCTCGCCCATGTCGGCGGCGTACTGAGCGTCCCCACCCAGCTGAGCGGACAGTTTCGCCTTGGCCTTGTCCGCATCGAGGGCACCGACCAGGCCGGCGCCGATTCCGGCGGCGAGCGCCCCACCGATCAGCGGCCCGTACTCGCGGGCCTTCTCCCCTGCGGCCTGGAGCTTGTCCTGGGCGCTGGCCAGGCCGCGGGCAAGAGCGGTGTCGTCCGCGCGGAGGTAGGTGACCAGCTCGCCAAGTTTCAGGGCCATGGGCTGGTCGCCTCCGAGCTATTCAGGTGGATTGAGCGCGCGGCTGAGCCGTGACTTGGTGAGGACCAGGCCCTCGATGCGGATTTGCAGCCACCGCCACGACCGGCGCCGCATCAGCGCCCGGTCGTCGACGTCGATGCCGTACTCGGAGTGCAGGTCAGCGACGATCAGGTCCCACTGTTCGAGGACCTCTGTCCACGTCCGCCCCTCGCCCGCCTGTTCCTCGATGAGCCGTTCCGGGATCTCGTAGTACTCGAAGAGCCCGGTTTCGGGGTCTCGGCGGCCGCGGCCGTATTGGTCCGCCCAGCTGCCCGGCGCTCCGCCCTGTTCGCCGGGCCCGGCGCTTCCCCCGGACGACCACCCGATTTCCAGTACCGCTCGGCCTCGTCCTCGTCCCGCACGATCCAGAGGTAGGCGACCCGACCGCAGAACTTGATGTGCTCGTGGAGGACCCCGTCGGCGACCATCAGGTCGTAGGCCGTGCTGAGGGTGCGCTGTTCCAAGGTCCGGATCCCTTTGCCGAGCTGGGGAAGCTCGTTCTCGATGGAATCGAAGACCTCTTGCAGCTCCTCTGGCGCAGTTGCCGTGCGGAGTCGTCCGGTGACCTCGGCCAGCATCTGGCACCACAGCCCGAGCTCGGCTGAAGCGGGCGGGATCACATACTCGCGCTCGACGCCGTGGCGGTCCGGCACGGCGAGCGTGAGCTCAGGGTTGAAGTACTCGCGAAGCCCGGAGAGCTTGGCCATCAGGAGACCACGAAGTCATTCGTCGTACCCGCGGTCTCAGCGGTGCCGGCCGGGGTCGTGACGGTGACGTCCTTCGAGCCTGCGGTGAGCGCCGGCTTGGTCGCGACGATGTGCCCATCGTGGATCACCGTGAAGTTGGGCGCCGCCGTGCCCCCGAAGCTCACCGCCGTGGTGCCGGTGAAGTGCCCGCCGTAGATGTTGACCAGGCCGCCCGCTGCGGTGCCGCCTGCGGCCGGGCTGAGGCTGGTCACGACCGGGGTCATGTCCGCATTCGGGTTGTCGATCACGCTTTGCGGGCCCTGGCCCTGGAGGACCAGGGACACGATGTCGAGGGCCTCGGGGCCACCGCCGTCCGGCGGGAACGCCTTGACGAAGACCGTGCCCTCTTTGCTGTTGCCGTCGTCGAGGCCTTCCTTGTCGTACCAGCGCACCGCGAACTCGCCGAGGTGGGTGGCCTGCTTGCCGGCCTCGTACTTGTCGCGGAGGAACCGGTGGACCGGGTGCACTGCGGTGCCGGCCGCGTTCTTGGAGAAGAAGATCTTCGCTTCGATCCGCCAGCTGACCCCGGTTCCGGTCTCGCGGTAGAAGCCGTTGTCCTCGTGGGTCTCGTCGGCCTCGGTTCGAATCTCTTCGACGAGGGTCACTTCCTGCTTGCCGATCAGCTCCTGCCAGCTGCGGGCTTCCCAGGTGCCGGTGTTGAGGTCGATGCGGTATCGCCTGGCGAGCGCGGTGACTCGGGTGGTGGGTGTGGCGGCCATGAGGTCCTCCTGATCAGTCGGTGCGGTTCGGGGTTGGCCTCATGGCCTGGACGTAGTAGTTGTGCGAGATCTCCCAGCGGCTGGCGCTGTCGCGGCCGAGGGAGGTGTACGACTGCCGCCAGACCTGGACGACAGGAATGCCGCCCCAGGTGAGGCCCTCAGCGCTGTCGAGAAGATCGAAGATCGCATCGCCGATGTCCGCAGCCGCGCGGGGATCTGTGGTGCCGCGTACGCGGATCTGGAGGCCCTGCGTCACGTCGGCCATCCCGGGCGGGGAAGCGACCACGTACGGGGCGAGGGTGATTAGCCGGTCCGGCCGGGCCGGGATGTCGAGCATCACGATCGCGACCTCGTCAGCTGTGTAGCTACCGCCCGGCCGCCAGACACCGACGCCTGCGGCCTGGAGGTGCTCGGCACAGCCGACCACGAGCCGGGAGGTCCAGCCGTCGCCGATCATCCGAGGAGCCCGCGCGGGCGGGAGGCAATGAGCGCGAGCATCGTCTCCTGCTCGTCGTTCATGGGATCTTCCAGGTATTTCGCCTGCTTACCGGCGTCGTGTCGCAGCGTCATGTCCTCGTGCTGGCGGACCGCGTACGGCCGGTCGTAGGAGACGGCGACGGTCTGCTCGCCGCGGTCGCTGGACACCTCACCGGATCGGGCCAGGTCGCCCTCCTCCAGCGGTGCGAGCTCGGAGGAGACCTGGAGCAGGTGCTCAGCAGCGAGTTCCAGGCCGTCGATCGACGCGCCGCGGAGCGCCGCCATGACGTCGTCGCCGCTCCAGTTCAGCTCGTACGGCTCATCTGCCATCGGTCACTCCAGGGACAGCTCGACGTGTTCGGGCAGGTCCAGGCCGTGGGCGTCGAGGACGGCAACGGCCAGGACGCGGGTAATGCGGCCGGACGGCAGGGTCACCCGGCTGCCGGCTGGAGCGGTGGTGCCCCGTGGGCAGAGCACCGTGGCACCCGATGTGTCGTTGTGGCCGGCCGCGTCCTGGGTTTGCACCGCGACGCGGCGGGTGGACTCGTCGACGACGCACGGGCCCACGACGACGGGGCTGCCGTACACGTCGCCGAACCCTCCGGCACCGGTGAGCGCCTCGACCGTGATCTCGTGCGGCTCCGGTACGTACTCCTCGACGAACTCGGCCCAGTTCACTGCTCACCTCTGCATCGGTCCGTGGCCGGTGAGCCCGGCCTGCTGGAGGATCGCCCAGGCCGAGGACCAGAGATCACCGACCTTGGCGGCACGGTCTTCGGCCGCCTTCGGCGAGACGGAGATCTTGCCGAAGGAGAAGCCACCGCCCTTGCGGCCGCCGGAGCCGGTCACGTCGCCCTGCTCCAGGCCGACCGCGATCTGCTCGAGCACGGCCTCCCGGAGCGCGGCGATCGTGGCCGGGTCGGTCGGGTCGTAGATCGCGCACAGGATCACCTGGTCGACCGCCCGGGACGCTCGCAGCAGGAGCTGCCGCGCGTTAGCGGGGGTGCGGCCGAGGTGATCGTGCAGCTGCGTGAGCGTCGCGTACGCGCCCGGGATCGTCGGATCCGGGGCGCTCGTCGACGCCGTGATCGAGGCGAGGGCACCGATGTTGCCGGCCGCGTCCCGGGCCCGCACCGCGAGGGTGTACGAGGTCGCCGACGCCAGGCCGGTGAAGGTGTACGCCGTCGCCGTGACCCCGGTCGCCACCACGGTGCCGTCACGCAGCACGTCGTACGAGGCGACGCCCACGTTGTCGGTGGCGGCCGTCCAGGTCAGGGCGATCTGCGTCTGCCCGGGTGTCGCCTGCAGGCCGGTCGGTGCCGACGGTGGCGTGGTGTCGGCGATCGCCGGGAACCCGTACGACGCGAGCGGCGCCGGGGTCGGCCGGACTAGACCGCTCGGGAACGGGTACGCCGGCGGGACCTGGCCGAGGTCGGCCAGCAGGTTGGTCAGGGCCTGCTGCAGGACCGGGGAGACGAGCGTGCCGCCGGGGTGCCGGTCGTGGACCTCGTCCAGGCCCCATGCGTATTGCACGGTGCCGGCCGCGAACACGACGGCGCCGGTGGTCGGCGACCGGTACGCGGTGATCGCGTGCGTGTACGGGCCGCTCAGGCTGTAGATGTTGCCGTCGTCGTCCGACAGCATCCCCGAGACGGTGTGGGTGATCTGAGACAGCCGGATCAGCCCGGACGGGGCCTCACTCGGAATCATGTCGGCCGGCTCGTCCGCCTCGAAGCCCACGATGCCCGCCGGGCTGGTCCAGACGTCGCTGCCGGTGAGGCCGGCCACCGTGGTCGAGCGCCACAGCGGCGAGCTCGCGTGCGCGGCCGTCGCACCCATCGGGTACGACGAGATCCCGTTCAGGCGGAAACGCTGCCCGTTGAGCAAGCTCGCAGGCCTGCGGTCAGGGTTGAAACTCCTGGTGTCCTGCCAGGTGCCGGAGTAGAGCCCGGTGGGGTTGAGCTGGCCGTCGTGCGAGTCCTTCCAGCAGTCGAACGTCCGCCGGTCTCCGCTCCACCTGATCCGCCAGAACGCCTCGTTGCCGGACAGGATCACCAGGTTTGACGCCTGGGTGGCGTGATCGTGGGCGGCCACGTGGGCGTCCCGCATGCCAGCTGACCAGTACTCGTCGTGCCCGGAGGAGATCACCGCATCGCGGCCGAGCAGCAGCGACGGGTCCGCGTCGACCTGCGCGCAGCTCAGGTAGTCGACGTCGTAACCGAGCCGCTCCAGCCAGCGGATCAGCGGATATTCCGCGTTCCAGAACGATGTCTGCGGCAGGTGCTGGCGGGTGACGAGGGGCCGGTCGTAGCTCACAGCACGGGCGCGGGTGGCCTGACTGAAATCGAAGCCCGTTGCCGAGCCGGTGCCATAGATCGAGCGGCCGTTGAGCAGGTCCGCCGGGTTCGTGCCGGCATGGTTGTAGGCCTGCCACGTGCTGTCGCTGAGCCGGACCGCGATCGAGGCCTTCCGGTTCGGGTCGGTCACCACGAAGGGGCCGATGTGCGAGCTCAACGCCGCATTGTCGTTCCGGGAGATTTTGATGATGTAGACGCCCGGTGTCAGGGTGCTCGCCGGCGTCCAGGTCGCGTTGATCGACCAGTTCGAGCAGCTGCCCATGAGCGTCGTCGGGTCGACGGTGCCTGCGGGCTGCGTGGTCTGCGGTCCGTTGACCGTGTCAACGGGCCGTGCCCCAGCGCCGCCGTAGTAGCCGAGTCGGTAGACAGTGCCGTTCCAGCTGGCCGCTGGACTGTGGACCTTGAGCGAGAGCGCCTGGCCGCGCGGCACGTGCGTTGACGTGGCGTAGCCCTGGATCGTCATGCTGCCCGCGCCGACGATGTCCCAGACGGACTTCGCGACGCCCTGGAGCCGGTTCTCCGCCTCGATCGCGGTCTCGGCGGGCGGCGGCTCCTCCGGCGGGTCACCGACCGGCTCCATGGCCCAGACGGCGATCTGCAGCTGCACGGCCGGGACGTTCGTGATGACCAGCTGGTGCTCGCCGGCCGCGACCACACCGGACGCCACGACCAGCCGGACCGATTCGCTGCCCAGGCCCGTCACGACCACGGTCTCGTCGACGGTGAGGGCGCCCGGGAAGACCGGTGCCCAGGTCGGAGGCTCACCGACCGTGGAGATCGCCACGTACACGCGGCACCCGTCCACCGCGGTGGTCACCGGGGTCAGCGCGAGCTGGCCGCTGTACGTGATCGAGTTCGGGTACGACGCCACGGACCCGGCGTGGACCGGGCCCAGGTCGTTGCGGCTCTCGACCCAGCCGGCCAGGCCGCGCGGCGCCGTCGGCGCCCCGGACGGCCGGTCCCAGGTCAGCGCGGTCTCGCCGCCGGTCGCCGACCGGATCCCGACGGACAGCTCGCCGTCGCCGAGCGGCTGCGCGATCTCGTCCCAGCCGGCCGAGTAAGCGACCAGCGCGGGTGCGGCGCCGACCGCCACGAGGGTGCGGCCGGCGATCGCGGCGGCCGGGTAGGTCGCCGCGTGCTGCACGCCAGCCACCGCGGCGGCGTAGGGCAGTTTCCAGTCCCGCGCCACCGCGGCCCTCCCGGATCAGATGCGTTCGGACTTGCCGGTTTCGAGGTTGTGGCGCAGTCGCACGCCGCCGACCTCGTACTCCTCGTGCCGGTCCTTGTCGGTGTCCCGGTTCGGATTCGCGCCGGGCGGAGTGGCCTCACCAGTTTTGACGTAGCCGACCACCGCGCCGACGCCCGCCTGAGCGGCCTCGGCGAGGGTCTTCCCGTCGACCACGACGGTGGAGACCCGCTCGGTCGGGTCGGTCGTGTCGGCCGGGCCGTCACCGGGGGCCGTGATCTGCCGTTCACCGGGCACCTGGCCCTCAGCGACGGTGGCCTCCGGGACTTCGCCCGGGGCGTGGCCCTCGGCCACCGCCTGGTCGGCGGCGGCCTGGGCGGTGGTTTCCTGCTTCGCCTTGCTCTGTGCGCGGGTCGTCATGCCCAGCGCCTCCCTTCAGGGTTGGGGCCGGTCGAGCCGATCAGCCGTTGAGAACGCCGGTGAGCCGGGCCGCGGCCTTGCCCGCGAACACCGCCACACCGGTGAAGAACTCGATCCGGGTGCGGTAGGCCGGCTTGGCGTCCAGCTCGCCGAGGTCTCGGACGTCGACACCGCCGTTGGTCAGGCCGGTGACGCCCTTGTCGCCCTCGTCCTGGCCGTACTTGACCGCGTAGATGGAGCTCGTGATGCTCGCGGCGGTGCCCTGGGTTTCGGTCTGCGGCAGGATCCGAACGCCAGCGGCCGTGTCGCCCGGGTCGAGCACCGGAATACCATTCCAGGTCAGGACGCGCTTGCCGGTCAGGTCCTCGCGGACGATCTCGACTCCACCCAGGCGCCGGCCCGCCGAGCGAACTTTGGCCTGGATGGCGTTGTTGGCGTAGATTGCGCCGTTCTCGCCGTTGAGGCCGGGCACAGCGGCGACGAGTTCGTCGAGCTTGTCGAAGAAGGCGTGCACGTCGCTGCCGCCGTTGCCGACGACCGGGATGCCGTTGGTTCCGGCAGCGATGACCTGGGCGCCGGTGAGCCGCTTACGGAGACCGTCGAAGCCGTTCGGGGCGTCACCGCCGCCGGCGACGTCGCCGTTGAAGAAGGCGTCCTGGAAGCGGTACGAGGCCGCCTTGACCTTCATCGCCGTCTGCACGGCCCGCTGGTCGTTGAGGTTCGAGCGGGTCTTCGCGATGAACGTATCGACGTCCGCATCGCCGCCGAGGATGACCAGCGACTCGGTCGCCTGGTTCACGACGCCGGTCGATTCGGTGTACTGGCCGTTGACGGCACGGAACTCGACGCCGGGGAGCGTGCCCTCGCTGTTGTAGGCGTAGGCGTTGCCCTCGATCTCCATCAGCGGGATGCGGTCGAGGACGGGGCTGGCCTGCACGAACATCTCGATGACGCCGCGCTGGAGGTCGTTCTGGCTCAGGGTCGCAGCCTGAGCGAGGGTCACTGCCACGGTGGGCTCCTAAGGAATCAGGTTTGGCTGTAGGCGTGCCGGAGCCGGTCGATGCCGGGTCCGATCTGCTGCTGCGCGCCGGCCGCCGGGGCCCCGTTGAAGTCGCCGCCCGAGCGCGCCGGGCCAGCCGGCGGAACGGTCGGCGCCGGGGGCGCAGGCGGGTTCGGCGGCACGGGTTGGCCGGGCGCTGGGTTGGCCGGGGTCGCGGCCATCCACGGGTTCGCCGCGAGAACGCCCTGGATCGTCCACTGGAGACGCTGGGCGTAGTCGGCGGCGGCCGGATCGAGCTGGGCCGCGGCCTGCTGCCAGGCGAGGCTGCCGACCAGGGCCTGCGGGTTGACGCCCAACTGCGGGGCGAGTGCCCACGCCTGCTGGGACACCGAGGCGGCGCGTAGCTGCGCGGTGTGCTGCTGCTGGTTGGCGCGGAGACGTTCGATCTCCTCCCGCGCGGCCCTGGGCAGGCGGGCGAGGTCGTACGTCTGGCCGTCGTCGCCCGGGTCCGCCGGGGGCGGGGGCGTGAAGGCGGCCGGCAGCATCGGGTATCCGGGCTGGGCCGGGTACGGCTGCTGCTGTGGTGCGGGCTGCTGCGGCTGGGCGGGCGGCTGACCGGGCGCCGGCGGCTGAAGCCACCCGGGCGGGGCGGCTGGCGGCTGCTGAGGTGCGGTCTGCGGCGGGTAGCCGGGCGGGGCCTGCGGGGTCGGGTACGGCTGGGCCGGCGGAGCGAACGGCTGGCTGGGCGGCTGCTGGGCGGGCTGCCCCTGCGGGACGGCCGGCGCGGCAGGCGGCGCAGTCTGCGGCTGCTGGGCGGGCTGGGTCATTGAGCCTCCTGGCTCGATCGGGTGGTGCTTTCCGCTGCGGGATTGCGGCGGAGGCTTGATGTGGTCCTTGCCGGGACGCCGTACCGTGCTCGCGTGATCACTCCACAGGGGACAGGAGCGAAGGTGCGGGCAGGTCAGGTATGGAAGGTGGCTGGCGCGGCGGCGGTAGCAGGTGTGCTGATCGCCTGCGGCAGCGGCGGGGCAGACACAGCATCTGAGGCACCTGCCGTGCCGGCGGCAACCGCTGAGGCACCGGCTGGTAGCGGGCTTGTACCCGAGCCGGACGCGGCCACGACCAAGAAGTACGTGGCCGCGCTGCGGAAGATCGACGCGGACATCGTCAACGACGATGACGACGAGAAGCTCGTCGATCGGGGCCGCGACCAATGCAGCAGCGTCAAGGAGTCACCCGATGACGAGAAGAAGCTGATCAAGCTGACCAACCAGCGGTTCATATCCCCGGATCACCCGGACGGCTTCGGCGACAAGAAGTCGAAGAAGATCCTGGCGGCGGTCCGGAAATACATCTGCCCAGACCTCTGATCAGCGCGGCGCTGATCCGGCACCAATCTGCTCGCGGTAGCTGAGGCGCTTCAGCGTGGGGTTGGCGGCCAGGTGCTGTCGCATCTGGCCCTGCCACAACACCACCCGGGCCCGCGCCTGGGCGGCGGCGGCCGGGGTCAGCGCGGCGAGTTCCCGCTCTTTCCACCGCCGGATCGCGCGCTCGATCGCACGCTGTCTCTGCCGTGCGGCGTCGCCGTCAGGATCGGCGGTGGGCTGGCGCGGCAGCCGGGTGATCCCCGGCAGGTAGCTCCGGACCGAGTGCCGGCAGTTCGGATGCTGGAAGCCCCACGATCGCGCGTCGTCCAGGGTCGCCCGGACATCGATCGTGACCGGCTCGCCAGTGGTCTGGTGCGCCACCTCGATCGTGCCGGTCGGCCCGGAGCCGATCCGGAGCACCCGCCCTTCATACGGCCGGCACCGTTCGCACTCCTGGGCCTCGTTGGAGACCACCACGAACGGCAGGCCTAGGCGGCGCTGCTTGTCCACCTGGCCCTGCACTGCGGCGCGCTGGGTGACGGTGCGGATCGCCATCTCGACGTAGCTGGACATGCGCCAGCGGCGGCCACGCGCGTCGACGAAGCTGACCACGCCCTGCTCGACGAGCCGGGCGTACGTCAGCTGGGAGGCCTCGCGCCGGGTGAGCCCGCCCGCGATGCTCGCCGCCGTGCCCTCGGCCACCACACGGCGGTAGACGTCCGTGATGTGGCGCAGGACGTTGCTGTGCCGGGCGCCGATGTCCTGGACGAGGGCCTGGGCGAGCGCCTCCATGGCCGCTGAGCGGGGCACCACCGCGGTGGCGGCGGCGCCGGCCGCCGCGCCGGCCGACAGCTCGGTCGGGATCTCCTCGAGGACGGACGCTCCGCCGGCGGCATAGGCGTTGGCGACGGCCTGGAGGACCGTTTCGGCCAGCTCGTCGCTGATGCTGTCGAGGATGTCCTGGCCCGCCCTGCGCAGCTGGCCGAGAGCCGCGAGTCGCTCGATGGCCCAACCGGGGGTGTCGATGCCGGTCGCGAGGTAGCGGGTGACGAGCCGGAGCAGACCATGCTCGCCCGCCCGGTACAGGTCGACCGTGGCGCGGATGATCTCGGTCAGCTTGTCGGGGTCGACAGCCACCGGCTACTCCTGGGGCGGGTCGGCTGGCGGGTCGGGCGGCTGGCCCGGGTCGCCGCCGGTTCGGCCGCCGTTCAGGCCGCCGATCACGATCTCCGGGTCCTCTCCTGCGCCGCCGGCCTGCTGGATCCGGTCGACCTCTTTCCGCACCTCGGTGTCTTCCCAGTCCGGGTGCAGGGTCTTGACCTTCATCCAGGTGGAGATCGACTGGGCCGCTTCGAGGAGCTGCAGGGTGCGGGCCTGCTTCTCCGGGTCAACGGAGACGGTGTCACCGAAGTCGATCTGCGGGACCTCGGGTGTGACGCCGGTGCCGAAGATCGTGGCGTCAACGATCAACAGCGTCTCGATGAGCGTGCCGAGCTCGGGCCGCCAGTGAATGATCTTCGAGTCGCGGCCGATGTCCGACTCCTGCTTCCGCGCCCCGACCTCGGTCGCGGTCACCGCGGTCCCGTCCGACATGCCGAACGTCTGGGCCGAGTAGCCGGCCGTCTCGACGATCGTGCGGGTCATCTGGTCGGCGATGCGCAGGTGCTGCTCGACGCGGATGTCCGGCTGGAACGTGTGCATCTGCATCGCCTGGTCGTCGCCGGACAGCGTTTCCAGGCCGACGAGGATCTCCCGAGCGGCCTCCCAGGTGGCGCCCTTGCCGGGTCCGTGGGAGGTCAGGTACTGCTGCGGGACGAAGACGCGGGCGACGCCCAGGCGCAGGTCACGCATCAGCGAAGACCAGGTTTCGTCCAGGCTGTCCAGCAGGCCCTCGGTGCTGTCGTAGTCGGAGCGGCCGAGGTCGCCGGCGCCCGGGATGTCCGCCCAGATGCGGGTCGGGGTGACGTTCGGGATGTACGCGGCGGTGAGCCGGCCGGGCACGGTGGTGATGGCGGCCGCCTTACCCGTCCAGGAGACGCCCTCCATCGACGTGAGCCAGGAGGTGTCCGCCCAGCCGCCGACGTCGACGGGGTCACCGAGTTGGTCGAGGGTGCCGTCGTAGACGCCGTGCCAGATGACGCCGGGCTCGTGCCGTTCGAGGTACCGCACCACGCGCTGGCTGTTGCGCTCCAGGATCCGCCAGAAAGTCACGGCCGTCAGCACGCCCCAGCGGAACTCTGGGACCGCAGTGCCGGGGTCGACGCGGGCGATCCACGGGCGCGGCCGGAGCGTCTTGTCCCAGACGATGCGCAGGTACGTGCCACTCTTGGCGGCGGCGACTTCGGCGGCGGCGAGGAACTCCGCGTGGGCGCCGTCGTCGATCAGCTCGTCGAGGCGGGCCTGGGTGTCCTTGTCGGTTGCCGTCAGGGTGGGCGGCTCCGAGAACAGCAGCCGTGCGCTCGTCTGGGCGATGTCGGCGGCGAGCGGCACGTGAAGCTTGGCACGGCGCTGGCCGTCCGGGACGTGCTCGCCCCAGAACCAGCGGGCCGCGGTGTCCTTCGGTCCGGGTTGGACTTCGGGGAAGGCGGGCCGGCTGCGGCTGTAGAAGTCGGCGAGCTTGTCGGGCTGGCCGGCGTACCAGATGCCCCACTCGTTGATCTTGCTGAAGACGGGCTCCAGGTGCTTCGGCGGCCACGCCTGCAGCGGGTCGGAGGGCAGCGGCATCAGTCCTCCTGTGAGGTGGCGCACAAGCGCGGGGGATAGAACGCGTAGCCGCACATATGAGCTGGCGACTACAACGTCACGCGGGCAAGTGGAGTCGTTCGCGCAGCTCACCACGCCAGGCGGCACGGGTGGTGTGGCCGATGTACCGCTTCGCGTCGGGGCCGTGGTCGGCCACCTTCATCGGCACGTCTTCGCCCTTGGCCGCGGCCTTGTCGTCCCAGGAGTAGCCGAGCGTCTCCCTGATCAGCTCCTGGCACGACTCGTGGATGTCGAGCAGGTCGAGGCTGTAGAGGGTGCTGATCGTGCGGATGCCGGGCAGCACGCTGTTGTCGGCGAGCATCGACGCCAGGCCGTCCTGCTGCAGCTGCACCCGGAAGCCGGTCGCGGACGGGTCGACGACGGCGCGTTCCGGCTGCACGCCGATCCGGTCCGAGCGGGGCACCGGTACGCCGCCGAGCCAGTGCCGGACTTCGCGGGAGTACTCAGCATCGGAGAGCTGCCGGCGCTGGCGTGCGGAGTCCCACCGCCAATCCGAGGTGATGTGCAGCTTCCGGTCCGCGCCCAGGCCCAGGAGGACCGCGTGGAACGGGTTGCGGGTGCCGTGGTCGATGCCCACGCCAATCCACCGGCTGATCGCCGGGATGGCGGTGACGACGTGCCGATCGGTGTCGAACATGTCGTAGATCGCGCCCTCGGCCGGCACCCACAGGCCCTGGATGTAGCGCTTGAAGAACAGGCCGACGTACTGGCGCTTCAGCGACCGGATGAAGTCGGGCGACAGGTGCGGGTTGTCGTCCAGGGTGAACGAGAACCGGTGCATGTCGAGTGGGTCGCCGTCTTGGCTGCGGGTGATCGCGCCGTCGTGGTCGAGCCACATCGCGGCCTGATCGAGGAGCACCTTCAGCCAGTGGACAGGGCCGGCCGGGTTGCAGGTGCCGAAGAACTGGGCGCCGGGGACGGAGAGCCGGGTGCCGAGCATGTTCCACAGGTCCTCAGGCCAGGTCGCGATCTCGTCGCCGTACGCGCCCGCCAGGGTGAGGCCCTGGATCTTCTCGATGGCACGGGCGTCGTTCGCGCCGGCGGTGTAGATGCGCCGGCCGAACAGATACAGCTCGCCGCTGCCGGACATGTACCGGCAGCGCTTGGACCCGAGCATGTCGATCATCGGGTCGATGACGTTGCGCTTCAGGGTCCGCTCGGTCTTGCCGAGCATGGCGAGGTTGCCGCCGGGCCCGTTGCGGACGTATTGCATCCAACGGAACGTCGAGGCCACAGTCTTGGAGGACCGGACCGCGCCTTCCCAGATGTTGTACCGGGCGGTGGCCAGCTGCACCGAGCGCTTGGCCTTGCCGGTCAGCGGTTTGATCATCAGTCGCCGTCTCCGGTCATGTGCTGGAGCCAGGCGTCGATGCCGGAGGTGGCCACGTCGGTGCGGTCGTAGTCGGCCAGCTTCATCGCGGTGTCGGCGAGCGCCTTGATGGACAGGGCGATGGCCTGCTTGTCACGGAACGGCGGCTCGTCGAGCGTGCGCTCGTTGTAGTCGTTTTCCTTACCGCCGAAGTTCCAGATCTTCGACGGGGCGAACATCTGGCCGGCGAGCCGCTGCGCGTTCTCCAGCAGGTCGACCTGTAGCTGTGCGCGGCGTGCGGCGCCGTCGGCCTTCTTCGCGGCGGTAGCCGCGGCCGTCCTGGTGCGCTCGAAGGTGAGCGGCGGGTCGTGCTCGGCGCAGATCTTGGAGACCGTGCGTCCGGAGCGGCCGAGGAGCTCGGCGATCGCGTTGCGGCTCAGGCCTTCGGCGTGGAGTTCGGCGACGCGCTGCCGTTCGGTGTCGGTGATGGGTGGGTGTCCGCCGGCCATGGTCACCCCACTTCACACAGTCAGTACCCTAGGGTATTGTCAGGGCATGACCTCCCTTTCCGAAGTTGCTGGCCTGCTGACCGCGCTCCAGACCCTGGAAAGCCTGCCCCCGCTGGAGCGCGTCCGCGCGGCCCGGGCGCTCAGCGACAGGGCCAAGACGGCGCTCGCCGCCGTGGGCGACGCCGCGGTGGTGGAGGCGCTGTCTGGCAGCTCGTACACGGCGGTGGCTTCCGAGTTGGGCGTGTCGGTGGCGACGGTCAACAAGGCGGTGACCAGGCACAACGCCCGCACGAAGGAGTAGTACCCGCTCTCGCCGCACTCAACTACCCTAGGGTGTTGCTTCGTCCAATACCCTAGGGTATTGTTGTCCTCATCGGAGGGAACACGATGAGGGAGCGCGAGATGTACGAGCTGATCGAGGTCGACCCGGCCACCGGCAACGAGGACCAGCTGATCACCACCGGCACCCTCCGCCAGGTCACCCGGGCGATGCGGGACCTGATCGCCGACATGCAGGAGGACTGGGAGTGCGGCGGCGCCTGGTCCTGGCTCCGGATCCAGCCGGCGGCATGAGGCGAGGGCCGGGAAACCGGCCCTTTTCTCGCACCTCACATTGGAACGTTTCAGTCCAGCGCTTCGCGGCGAGGGTTGGTGCGGGCCGGCTTCCCGGTCGACCCGCACCAACCCCATCGACCCCCGATGCATCCACCCCCTGGATGCACAACAGCCCGGATCCCTGGCGGGGGATTCCGGGCTGCGAGCAGACTCCTGCTGGCAGCAGTGTGACGTAGAGATCCACTCGCGTCAAGAACGACGCCCGCGGACGCTCCCCCGGTCCCGCATCTCCAGCTCAATGCGGCTCGCTTGACCGAGCGGGTACCGCACCTGAGGCCGGCCGTGGCCGTCCGCGATGCGGGCCTTGCGCAGCCCCTGATCGCTGGCCCAGTACCGCACGGCGCGGATGGTCACGCCGTGGCCGAGCTGGTCGGCGATCTCTCGGGCTGTCCCCCACAGCTCCCCGTCGACCAGGATCACGCCGAGACGCCCCCTAGAACCTCGCTCCGCGGCCAGGCGCTCCCGCACGTCGTGCACTCGATCACCCGGGCATCCAGCGGCGGCGACAGCCGCATGATCAGGCCGGTGGTGTCGCAGTCGGGGCACGGGATGCGCGGGACGAGCTGGCGGTCGTGGGCGATGCGGAGTTGGCGGCGGATGCGGCCGTCGATGCGGTCGAACCAGAGCCGGGCTCGGTCGGCAGCACGCGGGCTCATCGCCGGGATGGCGGCCTCCAGGTCGCGGACCGGGTGGGCGACGTAGCCGGTCCGCGGCACGTGCCGGCTGACGTTCAGCAGCTGCTCTTGGACCTCGGTGCGCAGTTCGGCGTACCGGTTGGGCCTCGTGGTGCCGACGGTGCCGGCCGCGTCGCCGGTGGGGTCGCCGTGCCCGCCGAGCGCGTGCCGGCGCCCGAACGTCGGCGACTTCAGCGGCTCGTACCGCGCGGCCTGTTCGGCACGGATGGCGCGGTACTCGTCGTCGACGCGGTCGTCCAGGGCGGCGAGCGCCGCCTCCAGGGTGTGGAGGGCGGCGCTGGCGCGGAGCTGATGGTGCTGGTTGGTCACATCTCTCCCTCAGGGAACCGGAAGCAGCCACAGTGACTTGGGCACTCCTCGCACACCGACCGGTGGCCGGGCCGTGCTGGCTGGACGAGGACACCGGCTTCACACCCGGCGCACTGAACGAGTCCGGCGCGGCCAGTGCGGATGGCGTGGTCTTCGCGGACGGCGGCGAGTTCGCGGGCGCTGACTCGCTGGCTCATGCCACGTCTCCGTTCGGCCCGCTCTGCTTCTGCGGGGCGACGAGGGCCAGCTTGTACTCGTACGCGGCGATGATCTTCAGCAGGTTCACCGCGGACGGCATCGTGCGACCGCGCTCGTACTCGCCGAGCTGCTGAAGGTTGATGCCGGTCTTGTCGGCGAGCTGCTGGAGGGTGAGGCCGTGGAGGTGCCGGATCTCGCGCAGGGCGGTGCCGAGGCTGGTGGTGCTGGGGACGCGGATGCTGCCGGGCCGGTTGTCCTCGTAGGCCTGGAGCATGCGGTCGTCGGGCTGGGGGTGACCGTGGTCGGTGGCCCATTGGCGGGCGGCTTGGGTGGCGGGGCTGACGGTCACTGTGGGCCTTTCGGGTCGAGCTGGAGCGGGGTTTTGCTGATCAGCCATTGGTTCACCGGTGGGCAGAGGATCTTGGTGCCGCTGGCGTCGTGTGTGCGGTGGGTGGTCCCGCAGCGGGCGCATTGGCGGGCTGCGGGACCGTGGTCGGTGTACCGAGGCGACGGCATCAGCCCGGTGGACTCGCATCCCGATCCGGTGCGATGGTGACTAGGGCACGCAGGTAGTTGCGGGCATCCGCCTCGGCGGCGCGCTGCTCCTGCTCGGTGAGATCGGCGAAGGTCGGGTAGAAGCCCGCGTTGAACGGGCTGCGGCGGGCCAGTTCTTGACGGGCCTCCGCGAGCATGCGTGCGGTGACCTCGACGCCGTTCACCATGATCGAGTCCGGGTCAGGCACGGTCGGCCTCCTCGGCGTCGCGGCCGCGGCGGTCGAGCGCCTCCACCCAGGCCGCGGCAACGGCGGCCACCTGGACCAGCTCGGTGCGCAGCTCGGCCGGCTTCTCCTCCGCCAGGGCCTCGAAGACCTCCTCCAGGAGGATGTGTCGCCACGTCAGCGGGCCGTGGTGTTCAAGGCCGGGCGTCTTACCGGCCGCGGCGTCGGTGGCGCGGCGCGTATCCCGGGCCAGCTCGTGCATGTAGCGCACCTGGAACACCTCCCGGGGGCCGGTGCCGTCGGGGTGGTTCTGCTCGCCCCACTTCTCGTCCTGCGCCACCCGCTCCCGGGCGACCTCGTCCAGGACGAGGGTGAGCGGCAGCGGCTCCAGCACGAGCTGGCGCAGCGGACCCAGCACCGACCGAGCCGCCCGCGCATCCGCGTGCGTCTGCAGCAGCGTCTCCACAACGGCCCGGGACGCGCCAGGAATGCACCGGCACGGAGAACACACCGTGGCGTCCTCCGGGTCGTACCCGGGCTCACACGGCCGGTTGATCGCCGTCTCCTGCGTGCGCGCGGAAGGAACCGAGGACGACGGCCAGGGCTCGGGGATGTCGACCGGTTCGTCCGCGAGGTCGAGGTAGTGGTGGTTGCCTTCGTGGCCGAGGAAGTGGCGGCATCGCTGGTGTTCGTTGTCTGTGTGGATGCAGCGCTGTGCGTCGACTGGTAGCAGGTCCTCGGTGAGGTGGTGGGCGGCTCGTTGGCGGTTGGCGGCGTCCTGTTCGGGTGTGAGGCAGATGGCGCCGGGGGTGTGTTCGGGGGTGCCGATGCCGAGGCAGGTGCAGCGGCAGCGGGCGGCCTGTGGGCCGGTCAGCGGGTAGTTCTGTTCGAGGTAGCTGTCGATGTCGCGGCGGATGGTGGTGCGGATCTCGGCCAGGGCCTTCTCGTAGGCGTCGACGGTGCCGTGTCCGGTGTAGAACGCGTCGATGGTGCCGAGGAACTGGCCGGTGATCATGGCGAGGTGGTCGTAGGCGAGGCGGTAGGCGCCGGCGCGGGCTTCGGCGGTGTCGAGGGCGGCCGCGGTGACGTACGGCCGGGCGGCTGGCGGGGTGGTGGGGTGGAGGTTCAGCACTGGGTCTCCTCGATCTGGTGGCGGATCTGTCGTGCTCGGGCGGGGGTGATCCAGGAGTCGGCGGGTTCGGGTTCCTGGGGCGTTCTGGTGGCTCGGGCCATAGCGCGGGCAACGGCGGCTGCGGCAGCGGCCTGTGTGCGTTTCTCGCCGGGCGTGAGGTGCCGGATCATGCGGCCTCGCGGCGGCTGGATCGCTTCTCAGCGCGGGACCGGTCAAGGGCTCGCTGCCGGATAAGGTCCGAGCCGGTCAGTGGGGGTTCGTCGGCACCGGGTACGGACCGCGCAACGACGTATTCCGCGAGGATTTCTCGGACCCTGTTCCGGTTGCGGGCGATCCGGGCATCGCGATCGGGGTCGTCTTCGAGCTTGCCGGGCGGCAGGGCGCGGACGGTGGTGGAGGCTCGGCGTTCGTCTCGGATGATCCGGGTCAGGCGTCGGATGTGAGCGGGCATGATCCGGTCGGTGGACTCGCGGAAGTGCCGGCTGACTGCGGCGCGGGCATCGGCGAAGTCAAGGTCTCCGAGGTCTTCGTGCCAGGCAAGGACATCAGCGTCGCCGATGGTGCGCTGGTCACGACCGGCGATGGCGCCGAGGAGTAGGGCGATTTCGGAGCGGGTCACTGGTCCTCCTGGGCGTACTTGGCGGCGAGTTCGAGGGCAGCGCCGACACGCTGGTCCGTGGTGGAGGGTCTGGGGGTGTGGCCTGAGAGGGCGACAACGTTGCCCTGCGGGCGGGCATTCATCACCTGGTTGACGACGCTGGGCAGCGAGGTGGGGTGCATGCCGCGGCCTTGCCAGTACTCCAAGGCGCGCTGGATGTCGCTGGGGTCGATGTCGTCGCGGAGTAGCTGGGCGACTTCGCGGCCGATGGCGTCGACGACTCGCGATGGTGGGCGTCGGGTGCAGGCGGTCATCCAGGCTTGGACGATCTGTTCGGCTCGTCCGGGGGTGCCGGCGGGGTCGTCCTCGCGCACGCGCGCGGCGGGGTTTTCCCTGTTCCCTGTTCCCTGTTCCCTGTTCCTTTCCGCCAGTGAGTCCTCAGCGAGTGGTGCGTGAGGGCTGTGTGAGGGCTCACTGTGCGGGGTGGTTTCCGCAGGTGGGGGCGCATAGCGAGGACTGGCGGGAGCGGTTTCCGCAGGTGGCGGAGCCGGGATCTTGCTCCGGGTGGGCCGGTTGATCCGCTGGTGCTCATTCCAGTTAGTGATGGCAAGGAATGAGCGCGCACCCACCGTGTAGCGAGTAATCAGTGAGGACTCACTGAGTGCTTTGAGGTCCAGTTCGACGTCGCTGGAGAGGCGGTCGTCGAGGGGCCACACGGCGGCCTTGATGAGCCGTGCATCGTCCACGCAGCGGCCCTCGTCATCGACGTGGGTCCAGAGCCCGATGAACGTGAGCCGTGCCTCCAGCGTCAGGCTCGCGATGGCCAACGAGGTGAAGAACTCGGGCTTAATGGTCCTGATGCGGGCCAACTGCTTGTCTCCTTGCTGAGGTGCTGGCCGGCCGCCTCTCGGCCGCCGGCCAGCGGGATCAGGCGGCGGCGCGGTGGCGCGCCCAGGCGGTGAGGTGGGCCCAGGGCCGGTCCGTGGGGACGGCGGCCGCGAGGATGAAGAGCAGCGAGGTCCGGTCGGCCGGGTCGGGCAGCTCAGCGAGAAGCCACCGGAGGTTGGCCTGGGGGTTGTCGTCCCGGACCCGCTCGACCAGTTGCACCGCCAGGGCGGCGAGCCGGTCGACGTGCTCCTCAGTTGGCTCCGAGCGACGCATGTCGAGGTGATTTGGCATGGTCAGTCCTCTCGCTCGCCGAGACGGCGTAGGTGCTCGTCGTGCTGCGCCTGGACGGCCGCCCGGTGCTCGGCCACCCGCGACGCGTCGTGGAGCCGGTGCGCCCTGATCAGGCGGCAGCGGCACACGCCCGGGCTGTCCTCGTCGAAGTCGTGCGGGACCGCCTCACTGGTCCGCTTCGGGCCCCTCAGCACCAGCTGGGTGGGCTTCGGCGTCAAGCTCATGCCGGCACCGCCTCACGCGCCTCGGCGTACGCCCGGCAGCTGCACGCGCGGCAGGCGCGGGTCTCGTCGACGTGGACGAGCTGGAGGTGCGCGCAGGCGCAGCGGGGCTTGCGCGGCGCCGGCGCGAACGGCGACACCACGGCGGCCGGCTTCGGCTCGACCGGGCGCACGTACTCCGGCGCGATCGCGGCCACCGCAGCGATCCGCTCGGCCGGGTCGGTCCGGTAGTCGGAGCCGATCCCGGCCAGCTCGTCGACGTCGTCCAGGCCGTACGGGTCCGGCTGGTCCGCGAGGATCGCGTCAGGGTGCTCCCGGACGGCGGTGGTCAGCCACGTCTCCGGCCCCTGCACCGGGCCGCGGTCGTAGTCGTCCAGCCAGGCCAGGCCGCCCCGGTCCAGCACACGGCGGGCCCGGGTGACGGCAACGTACGCGAGCATCAGCTCGTCGCGGCGCCACAGCGCCCGGCCGGTCAACCGGTCGCGGCGCGGCTCCCGGAAGTCGGCGCCGATCCGTACCCGGTCCCACTCCCGGCCCTTCGCACGGTGCCCCGTTGAGATGATCACGTCGGCGTGCTGCTCGTCGACGAGCGTGGAGACGACCCGGATCAGCTCCTCCGGGCCGTGGTCGTCGACCAGCTTCACGAGGACCTTCAGCGAGCCGGACGCGTCGTCCAGGGCGGCGTGCTCCTGGACCTGGGCCCAGGTCTTGAACGCGAGCAGCTCGGGGTGTGCCGTGCCGCGCCCGGCCATCAGGTCCATGGCGGCCTCGGCGAGCCGGATCAGGTCGTCGCCGCCGCCGACGAGCGCCGCGCGGCGGCCCGACCGGACGGCGTCGACGAGCTGGGCGATCGCGCCGGCGTTCGACCGGCACAGGATCGCGTCCGGCTCAGCGAGAGCGGCCAGGCTGGAGCCTGCTGGCTCGTACCCGCGCAGCCGCAGCGGCGCCCGGAGCAGGTCCAGCCACCGGTTCGCCTCGGTCGCGATCGCCGGGCCGAATCGGAAGGACTGCGACAGGGTGAGCCGCTGGTCCGCCTGGAACTTGGACATGGCGTCGATAGCGCCCCGGAACCCGTAGATGGCCTGCGCGGAGTCGCCGACCATGATCCGTTGCGCGTGGTCCTGGAAGTGGAACAGCGACGCCATCACCGGGGACAGGTCTTGCGCCTCATCGAGGAGCACGTAGTCGACCGGCATCCGCGGCCGCGACAGCTGGTAGATCTTGAGGTAGACGTCGTGCGTGCACTGCAGCTTGCCGCCGCGGGTGAGCTGGAGATCGTCCCAGGCCTTGCGGGCGTACTTGACCAGGTACGCGGCGAGCTCCGCGTTCTCCGTGTGGGTGTAGGCGTCGATCGGCTCCAGGTGCTGGACGCCCGGCTCCTGGTCGGCCGAGTTGAGGAACCGGCCGACCATCGCCATGACCATGCGCGCGAGGGTGATCGGGGACAGCGGCGCCAGGTCGGGCGCGAGCTCCACCGGGCTGTTGATCCCGAGGGCCTCGGCCGCGGCCTTGGCCGGCACACGCGGTCCCTTGATCCGGTCGATGTAGTGCCGGCCGACCGGGCCGAACGCCAGCGAGTGAGCGGTCCTGCAGTCCACGGTGCCCGGGAAGTCGCGCTTCGCCTCGGCAGCCAGGGCCTTGTTGTACGCGACGTACGCGCCCCTGCGGGCCGGCTGCGCCTTGGCGGCCATCTTGAGCGTGCTGCTCTTGCCGCAGCCGGCACCGGCCTGAACAACGATGGTGGGCCGGTCGGCCGCGGTGAAGGCGTCGATCACCGCGGCCTGCTCGTCGGTGGGCCGGTGGTTCATCGGGCACCAGCCCCGGCCAGCTCGGTCTCGGTCGGCGGTGTCTGCTGGGCGATCCACCGCTCCAGGCGGTCGCACACCTCACGGACCTCGGCGTCGGTCAGCTCGTTGGTGCTGCCGACGTCGTGCCCGACGACGTTGCCGACGTAGGCGAGCCGCTCGTCCCGGTCGGTGATCTCCGCCTGACCGAACAGCGCCATCATCCGGCGGCGGGCCGCGTCGTTGCCCGGGTTCTTCGGCTCGGCCGCGGCGACCAGCTCGGCGCGGCGCTTCGCCAGGGCGTTCTTCAGCGTCTCGAATTCGTCGTCGGTCAGCCCGGTGGCCGCCTTGCACGCCTCGACCGCCGCGCCGTACTGCTCGCGGGTGGCCACCGAGCGGATTTGCTCGAGTAGCTGGTCGACCAGCTCCGGCTCGGCGGCCTGCAGCTCGGCCAGGTCTCGGGTGTGCGCCTGGGCCGGGTCGCAACGCAGCATGTCGAACACGACGCCCTCCACCGACCAGTCCCGGGCCAGCGGGAGCGGGTCGTCATACCCGGGGCGAACGCCCAGGTGCACAGACCGGAGGCCGACGATGGTGCCGGGCTTGGACCGGTCGAGGCGGATCCAGCAGGAGACGTCGAAGCCGAGTGTCTTGTGGCCCTCGACCTTGTATTCCTTGGTGTTCGCGATCGGGGCGCCCTTGTCGTCGAGCGCGGCCACGTCCTTACCGCGGGCGGTGAGCAGCACGATGCCCGGGAAGGTCATCAGCGTGGTCATGAGCTTGCGGTGACGGCCGCCGGCCTCGTTCCACAGGTCCATCGAGATCTTCGGCTCTTCGTCGGCCGCGAGCTGGGGCTTGCCGTACTTGCGCGCCTTGGCGTTGTGGCGCTGGCGGGCCTTGTCGCTCGCCCAGTCCTTGAGCATGTCCCACTCGGCGGTCATCGAGTCGATGACGAGCACGACCGGGGGCTTGCCCGCGGCGAGAGTGCGCTGGGCCTCGGCCTTGACGGCGTCGACGGCGGCCTGGATCTCGGCCCACGTCCACTTCTCGCCGGTGGGCTCGATGATGTCGTAGTCCGCGCCGGGGATGGCGCCGTACTCGTCGGCGGCACCCTCTCCGAGGTCGATCCAGTACATCTGGCCGATGCGGGGCGAGGTGGAGAACTGGGCGCACGCCCAGGACTTGCCGGCCTTCTCGCCGCCCTCGATCAGGATCAAGGGCCACGGGACGCGGCCGGTGGGCTTGCGGGTACGCAGGGCGGTCACTTCTGCTCCTCGGCGTAGGCGGGACCGTCGACGCGGCGGAGCAGGCCGCCGACGTTGACCAGGACGATCGGGGTGGGGAAAGGGGAGGCCGGCGGCTCGGCCGGCTTGGCGAAGATCGGCGAGCTGACGGGGATGACCGGCGCGTTCGCGAACAGGGCCATGGCCTCGGCGTGGAAGGCCGCGCAGTCGCAGATGTCGCCGAGCAGGACACCGCAGCAGTCCTTGACCGGGATGGCGTGGAGGGTGCGCTCAGCCATGGGTCACCTCGGCGGCGTGACGTGGCTGGTAGCGGCCGGTGGCCTGCCCCGAAGGCTGCACCTCCGGCTCGCCGGCCACAGCCGGGATCTCCTGGGTGGTCTCCGGCGCCTCGCCCAGGTCGACCGGGTTGAGCACCGGGCCCGGCGCGATCACCGGCTCGCTGAACAGGCCGAGCCCGCCCAGGACGAGTAGCGCGGCCAACGGGACGAAGCCGATGGCGGCCAGGATCCCGGCGAAGATGGCGCTGTTGGTGGAGCCGAACGTCGGGAAGGCCAGCATCAGCTGTCACCCCGCTCGTGCTCGGGTGTGACGGCCGGGGCGGCGTACCACTCCCGTAGCTCGGCGATCTCGCGCTGCTCGCGCAGGACCCGGTCGAGACGGCGGTTGGTGATGGTCCAGCGGCGCCGGTACTCGTACGCCAGGACCATGAGCACCGAGATGGCGATCGCGACCAGCAGCGCGGTGAGGATGATGGCTGCGAGGACGTCTGCGCGGATCATGCGGCACCGCCCCGAGCAGCCGCGACCTCGGCCTGCAGCTCGGCGATACGCGCGAGCAGAATCCGGGGATCCTCCTCGGCGGGCCGAACGACGTAGCCGTATGCCGTAATCGTGAGGGGACCGATGAAGCCTCGGGCCTTGTAGTCGTCGTATCCGGTGCTATCGCTCTTCCGCTCACCGACCTTTCCGAGGAGGTGGGCCCCGAGCGCATCGACGTTCTGGATCAACGTGGCGGAGGCCTCAGCGGTCCCGGCGTGGCCGTAGAGCACGTGGAAGTAGAGGCCAGACGGCAGTGCACCGTCGAAAGTGGCGAGCTTGTCGCCGAGGTTGTGCAGCGCGGCGGCCAGCTCGGTGCTGCGGTTCCACTCACCCTGGTTGGCGAGCGCGCCGTTCAGGCCGGCCGCCATCGCGTGGGCGGCGTTGAGCTGGGCGGTGATGTGGTCGGTCTCGCCGATGTCGTCGACCAGGTCGAGCTTCCACTCGACGGCGATGTCGGCTTCATGCTTCGGGCGCCCGGGCAGGGACCACAGGTTGTCGGCGGCCTGGAGGTGCGGCAGGGCGGAAAGCCGCCGGATGCTCACCTCGACGTGGCTCTCGGGGCCGTACTCGTCGAGGGCCTTCTCGACGGTGGTGACGAAGCCCTCCTCGTCGGCGAGGAACACCTGCCAGAGGCTGGCGTTCGCCGGGGGCTGGTAGGTCATGGGATGATTCCTTTCGTCTGGCGGTCCCGGTCGTGTGCAGCGATTGGCGGGGCCGCTGGGCGTTTTCTGTGGCCTGATCAGGCCGTGATGGCGGGCTGCTTGCCCATCCGGTGGATCTCGGTGATGTCCTCGCGGGAGAAGCGGATGTCCCGGCTCCCCAGGCGCGTGAACGGGATCTTGCGAGCGGTAACCGCCTCGTCGACCCAGCTCTTGGGCTTGCGGATCAGCTCGGCGAGTTCGGCCTTCGTGATCAGTTCGAGGTCTTTCATCAGGTCGTCGCCTCGTTCCGTTCGAACAGGTACTCGACGTTGGTGTTGAGGGCCGTCGTAGCCGCCGCGATGAAGCGGGTTCCGGGCTTGATGTGGCCTCGCCGGATGCGGCCCAACGTGGTGTGGCTGACGCCGATGCCGGCTGCTCGCTGCTGGTCGGTCTTCCAGCCGCGGTGCCCCGTCAGCTCGTCGAACCGAGCCAGATTCAGCGCGAATCCAAGGTCATGTTCGTGCACGAACAGAACCGTACTCCTTATGTGCGCGTGCGCACAAGGCGGAGGTACGCGGGTTTCTTGGGAAGTTTCGCGGTGCTAATGTGCGTCCATGCACACAGCCCTCGCGCTTGAGAACACGCCCTTCGTGGGCGTAGCGACCGTTCGGCGACGATCGAACGAAGATGTGCGTGCACGCACACGAGTGACAGGTCGCGCACCGGTACCTAATGTCGTGCACGTGCGCACGATTGAATGGCCCGAGCAGGAGGCCTTCCTCCAGCAGCTCGACGCCGTCAAGCAGCGGCACAAGATCCGTCACGACAGCGCGCTCGCCGAGCTGGCCGGCATCAGTCACACCGCCGTCTCCAACTGGCGTAACCGCAAGGCCCGCCCGTCGCTGACCGCCATCACTCGTATCGCCGAGGCGATCGAAGAGTCACCGCAGCCGCTCCTCGCCGCCGCCGGCCTCATTGAGGACCAGGACGACAGCATCGACCCGCTGGCCGGCATGCCCGACTCAATCCGCAGGATGGTCGCTCTCTACCGCGCCGGTGACGAGACTCTGCGCACGCGCCTGGAAATGGGCGCCCTCGTGCTCACTGAGTTCGCTGACGACCACGTGCGGCTCAGCAGCACCCAGAAGCGCAGCTCCTAAGCGCGCTCTTCGCCGGGCCGAGTAGCCCGCGACTCGTCTCTTTCTCCCGCTCTTCCCTGATGAGGCGGAAGTCCAATGTGGATTGAAAAGCACGGCCCCAACTGGCGTATCCGCGAGGAGATCGCCGGCCGCAAAACCACTCTGAAATCCGGTTTCCCGACCAAGACCAGCGCCAAGGCCGCGATGAACGCCATGAACACCGACCGGGCTCGCGGCGACTTCATCAACCCGCAGGACGGGAAGGTGACGCTCGCTCAGTTCGTCAACGACTTCTGGCCCGGCCACGAAACCGGCTTGAAGCCGTCGTCGCGGCGGACCCAGGGATCGAACCTGCGCGTGCACGTTCTGCCGCAGCTGGGCCTCTACCGACTCGACCAGATCGACACCTTGGTCGTGACGCGGTTCGTGCACCGCCTGGTCAACGGCGACCCGGACCCCGTCGACGGGCCACCCCGTAAGCCGCTCAGCCCCGGGTCGGTGCGCAACGTCTACGGCGTGCTGCACACGATCCTCGGCGCCGCGACCAAAGCCCGCATGATCCCGTTCAATCCTGCGATCGGAGTGAAGATGCCGCCCCGCGAGCACCACGAGATGAAGTTCTGCACGCCCATCGAGATCGAGCGCCTGCTGGCCGCCTGCACGGGTGATGACGCGCATTGGCGCCCGCTCGTGATGCTGCTCGTGACGACCGGGCTGCGCTACGGCGAGGCCCACGCCCTGCAGGTCGGCAAGGTCGATCTGTTCGCGGGAACGGTGCAGGTGACACGAACGGCGTACGAGGCGAGCGGTGGCCGCTTTGTCTATACGACGCCGAAGACCAGGTCTTCGCGGCGGACGGTGCGGATCCCGCAGGAGCTTGTGCTTGAGCTGGCTCCGTTGCTGGCGGGCAAAGCCAGTGATGCTCTCGTGTTCACGATGCCCGACGGTAAGCCCATCACGGGGACCTTCCGGAAGGGAACGTGGAAGCGGATCACCAGCCGGGCCGGGCTGACCGGGCTGCGGCTGCACGACCTGCGCCACACGGTTGCGTCGTTGCTCATCTCCGCGAACGTCCCGTTGACCGCGATCCAGCGGATGCTCGGTCACACGTCGATCAAGATGACGTCAGATCTGTACGGCCACCTCATGCCGGAGGTCAACGAGTCGATTGTCGACACGCTCACCGAAGTCCTGAAACGGGGCTCCAGGCGCGGCGGGACGACAGGGATTCCGGCGTGGCCGGTGGAGGGGGAGCGTGGGGGGAATCTGGGGGGCGCGTGGGGGATTCCAGCCCTGCCCAATCCTGCCGAATCCTGA

Protein sequences of DBSCAN-SWA_1

>NC_017093|256658:289350|261114_261912_-|WP_014440360.1|DBSCAN-SWA
MITLTYDDAVARVRLSATVVGTVAYAVIDRSLTGWRWTTVRGGGRRAPAAGAVALDDYEFPPGKPVTYRVRGYTSGNVLVSTETAVITAVIDRVWLKSVARPFLNRAVTVRTAPAISQPTRSGSFAIKGRSLPVEVAEVRGPREWELEVRTDDPGDTRALELMLALGDVLYLQVPPTYDGDVPTGYVKVGTSSHRRLSQLPGDRRRVWSLPMSERAAPGPDVVGAAATWATLLAEFGTWADVIATFATWADVAAYVADPETVIVP
>NC_017093|256658:289350|259993_261118_-|WP_014440359.1|DBSCAN-SWA
MRPVSDKFLRTLTGSHTAVVRAWVVTPGQTGVTPIGTEVRIIDGEVRLDSGQALRSQLSLEIDGTGLWPQYGSDLLTPYGNEVFVERGIAYGNGAVEWVSLGYHRINTIEQDVPPNGPIEVTAVDRMAAIVDSKLTSPVQFGAARTNASVVAQLVTEAYPAAVIEWDEPTVANAPIGRTVAVEEDRYGFVDELITGLGKRWYFDHRGVLKISDLPSTATPVWTVAQGEGGVLVEASRSLSRVGTYNGVLAKGEGLDTTAPARGLAVDAGATSPTRWGGPFGRVHRTFSSPLLTSNAAATAAARTLLKRALGLPYNVDFRSIVNPAIEPDDPVAIEVDGGQTETHVIDTLTIPLTVDESMQATTREQTLITIGET
>NC_017093|256658:289350|265366_265810_-|WP_014440365.1|DBSCAN-SWA
MIGDGWTSRLVVGCAEHLQAAGVGVWRPGGSYTADEVAIVMLDIPARPDRLITLAPYVVASPPGMADVTQGLQIRVRGTTDPRAAADIGDAIFDLLDSAEGLTWGGIPVVQVWRQSYTSLGRDSASRWEISHNYYVQAMRPTPNRTD
>NC_017093|256658:289350|273300_274884_-|WP_014440374.1|capsid|DBSCAN-SWA
MPLPSDPLQAWPPKHLEPVFSKINEWGIWYAGQPDKLADFYSRSRPAFPEVQPGPKDTAARWFWGEHVPDGQRRAKLHVPLAADIAQTSARLLFSEPPTLTATDKDTQARLDELIDDGAHAEFLAAAEVAAAKSGTYLRIVWDKTLRPRPWIARVDPGTAVPEFRWGVLTAVTFWRILERNSQRVVRYLERHEPGVIWHGVYDGTLDQLGDPVDVGGWADTSWLTSMEGVSWTGKAAAITTVPGRLTAAYIPNVTPTRIWADIPGAGDLGRSDYDSTEGLLDSLDETWSSLMRDLRLGVARVFVPQQYLTSHGPGKGATWEAAREILVGLETLSGDDQAMQMHTFQPDIRVEQHLRIADQMTRTIVETAGYSAQTFGMSDGTAVTATEVGARKQESDIGRDSKIIHWRPELGTLIETLLIVDATIFGTGVTPEVPQIDFGDTVSVDPEKQARTLQLLEAAQSISTWMKVKTLHPDWEDTEVRKEVDRIQQAGGAGEDPEIVIGGLNGGRTGGDPGQPPDPPADPPQE
>NC_017093|256658:289350|282188_282410_-|WP_041829497.1|DBSCAN-SWA
MSLTPKPTQLVLRGPKRTSEAVPHDFDEDSPGVCRCRLIRAHRLHDASRVAEHRAAVQAQHDEHLRRLGERED
>NC_017093|256658:289350|280575_281028_-|WP_014440386.1|DBSCAN-SWA
MTRSEIALLLGAIAGRDQRTIGDADVLAWHEDLGDLDFADARAAVSRHFRESTDRIMPAHIRRLTRIIRDERRASTTVRALPPGKLEDDPDRDARIARNRNRVREILAEYVVARSVPGADEPPLTGSDLIRQRALDRSRAEKRSSRREAA
>NC_017093|256658:289350|276787_277042_+|WP_014440377.1|DBSCAN-SWA
MTSLSEVAGLLTALQTLESLPPLERVRAARALSDRAKTALAAVGDAAVVEALSGSSYTAVASELGVSVATVNKAVTRHNARTKE
>NC_017093|256658:289350|284211_285456_-|WP_014440391.1|DBSCAN-SWA
MTALRTRKPTGRVPWPLILIEGGEKAGKSWACAQFSTSPRIGQMYWIDLGEGAADEYGAIPGADYDIIEPTGEKWTWAEIQAAVDAVKAEAQRTLAAGKPPVVLVIDSMTAEWDMLKDWASDKARQRHNAKARKYGKPQLAADEEPKISMDLWNEAGGRHRKLMTTLMTFPGIVLLTARGKDVAALDDKGAPIANTKEYKVEGHKTLGFDVSCWIRLDRSKPGTIVGLRSVHLGVRPGYDDPLPLARDWSVEGVVFDMLRCDPAQAHTRDLAELQAAEPELVDQLLEQIRSVATREQYGAAVEACKAATGLTDDEFETLKNALAKRRAELVAAAEPKNPGNDAARRRMMALFGQAEITDRDERLAYVGNVVGHDVGSTNELTDAEVREVCDRLERWIAQQTPPTETELAGAGAR
>NC_017093|256658:289350|287637_288054_+|WP_172666557.1|DBSCAN-SWA
MRTIEWPEQEAFLQQLDAVKQRHKIRHDSALAELAGISHTAVSNWRNRKARPSLTAITRIAEAIEESPQPLLAAAGLIEDQDDSIDPLAGMPDSIRRMVALYRAGDETLRTRLEMGALVLTEFADDHVRLSSTQKRSS
>NC_017093|256658:289350|285705_285993_-|WP_014440393.1|DBSCAN-SWA
MLAFPTFGSTNSAIFAGILAAIGFVPLAALLVLGGLGLFSEPVIAPGPVLNPVDLGEAPETTQEIPAVAGEPEVQPSGQATGRYQPRHAAEVTHG
>NC_017093|256658:289350|279293_279683_-|WP_051042365.1|DBSCAN-SWA
MRQLVLEPLPLTLVLDEVARERVAQDEKWGEQNHPDGTGPREVFQVRYMHELARDTRRATDAAAGKTPGLEHHGPLTWRHILLEEVFEALAEEKPAELRTELVQVAAVAAAWVEALDRRGRDAEEADRA
>NC_017093|256658:289350|269833_270802_-|WP_014440370.1|DBSCAN-SWA
MAVTLAQAATLSQNDLQRGVIEMFVQASPVLDRIPLMEIEGNAYAYNSEGTLPGVEFRAVNGQYTESTGVVNQATESLVILGGDADVDTFIAKTRSNLNDQRAVQTAMKVKAASYRFQDAFFNGDVAGGGDAPNGFDGLRKRLTGAQVIAAGTNGIPVVGNGGSDVHAFFDKLDELVAAVPGLNGENGAIYANNAIQAKVRSAGRRLGGVEIVREDLTGKRVLTWNGIPVLDPGDTAAGVRILPQTETQGTAASITSSIYAVKYGQDEGDKGVTGLTNGGVDVRDLGELDAKPAYRTRIEFFTGVAVFAGKAAARLTGVLNG
>NC_017093|256658:289350|259280_259994_-|WP_014440358.1|DBSCAN-SWA
MADDELVELLRPPDAGPGVQFRQGVVMSWNQETAENLVAVDETVMANLSILNTSEAAILNIGDVVSILVSGNTWGILGRFTIPGSPEAVSALSSLRTQSASVTGLESFTSTSFKAGSGPVVSIVVGKSGRLMVFLAAEISAQGTTAAANTIIAGGDMGFALSGANTLGAASSRAYVVSGNILVSSSAVTFGTTGAAGRLVLLEGLTPGLTTITAMYRRRGGAVQANFENRNITAMAL
>NC_017093|256658:289350|266511_269376_-|WP_014440368.1|DBSCAN-SWA
MARDWKLPYAAAVAGVQHAATYPAAAIAGRTLVAVGAAPALVAYSAGWDEIAQPLGDGELSVGIRSATGGETALTWDRPSGAPTAPRGLAGWVESRNDLGPVHAGSVASYPNSITYSGQLALTPVTTAVDGCRVYVAISTVGEPPTWAPVFPGALTVDETVVVTGLGSESVRLVVASGVVAAGEHQLVITNVPAVQLQIAVWAMEPVGDPPEEPPPAETAIEAENRLQGVAKSVWDIVGAGSMTIQGYATSTHVPRGQALSLKVHSPAASWNGTVYRLGYYGGAGARPVDTVNGPQTTQPAGTVDPTTLMGSCSNWSINATWTPASTLTPGVYIIKISRNDNAALSSHIGPFVVTDPNRKASIAVRLSDSTWQAYNHAGTNPADLLNGRSIYGTGSATGFDFSQATRARAVSYDRPLVTRQHLPQTSFWNAEYPLIRWLERLGYDVDYLSCAQVDADPSLLLGRDAVISSGHDEYWSAGMRDAHVAAHDHATQASNLVILSGNEAFWRIRWSGDRRTFDCWKDSHDGQLNPTGLYSGTWQDTRSFNPDRRPASLLNGQRFRLNGISSYPMGATAAHASSPLWRSTTVAGLTGSDVWTSPAGIVGFEADEPADMIPSEAPSGLIRLSQITHTVSGMLSDDDGNIYSLSGPYTHAITAYRSPTTGAVVFAAGTVQYAWGLDEVHDRHPGGTLVSPVLQQALTNLLADLGQVPPAYPFPSGLVRPTPAPLASYGFPAIADTTPPSAPTGLQATPGQTQIALTWTAATDNVGVASYDVLRDGTVVATGVTATAYTFTGLASATSYTLAVRARDAAGNIGALASITASTSAPDPTIPGAYATLTQLHDHLGRTPANARQLLLRASRAVDQVILCAIYDPTDPATIAALREAVLEQIAVGLEQGDVTGSGGRKGGGFSFGKISVSPKAAEDRAAKVGDLWSSAWAILQQAGLTGHGPMQR
>NC_017093|256658:289350|257131_257476_-|WP_014440354.1|DBSCAN-SWA
MTTAVARWLTSRPADIAWRLMAAVALLLSVMIGVRQVQMTSCQARYNESANSSTRARAEAAEADRQALDELLRVVADQPDAALSEIRRYNMARAQADEQRRLNPVPPSPQETCG
>NC_017093|256658:289350|277128_277314_+|WP_014440378.1|DBSCAN-SWA
MREREMYELIEVDPATGNEDQLITTGTLRQVTRAMRDLIADMQEDWECGGAWSWLRIQPAA
>NC_017093|256658:289350|256658_256898_-|WP_014440353.1|holin|DBSCAN-SWA
MFKKVFWLATGERAVKSSAQALLLLWGGDAFNLFDVDPLGAAGIAGGAAVLSVLTSIVSTTVGDSTDPSLLPTSATADR
>NC_017093|256658:289350|286992_287184_-|WP_014440396.1|DBSCAN-SWA
MKDLELITKAELAELIRKPKSWVDEAVTARKIPFTRLGSRDIRFSREDITEIHRMGKQPAITA
>NC_017093|256658:289350|279073_279301_-|WP_014440383.1|DBSCAN-SWA
MPDPDSIMVNGVEVTARMLAEARQELARRSPFNAGFYPTFADLTEQEQRAAEADARNYLRALVTIAPDRDASPPG
>NC_017093|256658:289350|271767_272163_+|WP_107088759.1|DBSCAN-SWA
MAGAAAVAGVLIACGSGGADTASEAPAVPAATAEAPAGSGLVPEPDAATTKKYVAALRKIDADIVNDDDDEKLVDRGRDQCSSVKESPDDEKKLIKLTNQRFISPDHPDGFGDKKSKKILAAVRKYICPDL
>NC_017093|256658:289350|285452_285713_-|WP_014440392.1|DBSCAN-SWA
MAERTLHAIPVKDCCGVLLGDICDCAAFHAEAMALFANAPVIPVSSPIFAKPAEPPASPFPTPIVLVNVGGLLRRVDGPAYAEEQK
>NC_017093|256658:289350|282406_284215_-|WP_014440390.1|DBSCAN-SWA
MNHRPTDEQAAVIDAFTAADRPTIVVQAGAGCGKSSTLKMAAKAQPARRGAYVAYNKALAAEAKRDFPGTVDCRTAHSLAFGPVGRHYIDRIKGPRVPAKAAAEALGINSPVELAPDLAPLSPITLARMVMAMVGRFLNSADQEPGVQHLEPIDAYTHTENAELAAYLVKYARKAWDDLQLTRGGKLQCTHDVYLKIYQLSRPRMPVDYVLLDEAQDLSPVMASLFHFQDHAQRIMVGDSAQAIYGFRGAIDAMSKFQADQRLTLSQSFRFGPAIATEANRWLDLLRAPLRLRGYEPAGSSLAALAEPDAILCRSNAGAIAQLVDAVRSGRRAALVGGGDDLIRLAEAAMDLMAGRGTAHPELLAFKTWAQVQEHAALDDASGSLKVLVKLVDDHGPEELIRVVSTLVDEQHADVIISTGHRAKGREWDRVRIGADFREPRRDRLTGRALWRRDELMLAYVAVTRARRVLDRGGLAWLDDYDRGPVQGPETWLTTAVREHPDAILADQPDPYGLDDVDELAGIGSDYRTDPAERIAAVAAIAPEYVRPVEPKPAAVVSPFAPAPRKPRCACAHLQLVHVDETRACRACSCRAYAEAREAVPA
>NC_017093|256658:289350|266163_266508_-|WP_014440367.1|DBSCAN-SWA
MNWAEFVEEYVPEPHEITVEALTGAGGFGDVYGSPVVVGPCVVDESTRRVAVQTQDAAGHNDTSGATVLCPRGTTAPAGSRVTLPSGRITRVLAVAVLDAHGLDLPEHVELSLE
>NC_017093|256658:289350|274960_276256_-|WP_107088760.1|terminase|DBSCAN-SWA
MMIKPLTGKAKRSVQLATARYNIWEGAVRSSKTVASTFRWMQYVRNGPGGNLAMLGKTERTLKRNVIDPMIDMLGSKRCRYMSGSGELYLFGRRIYTAGANDARAIEKIQGLTLAGAYGDEIATWPEDLWNMLGTRLSVPGAQFFGTCNPAGPVHWLKVLLDQAAMWLDHDGAITRSQDGDPLDMHRFSFTLDDNPHLSPDFIRSLKRQYVGLFFKRYIQGLWVPAEGAIYDMFDTDRHVVTAIPAISRWIGVGIDHGTRNPFHAVLLGLGADRKLHITSDWRWDSARQRRQLSDAEYSREVRHWLGGVPVPRSDRIGVQPERAVVDPSATGFRVQLQQDGLASMLADNSVLPGIRTISTLYSLDLLDIHESCQELIRETLGYSWDDKAAAKGEDVPMKVADHGPDAKRYIGHTTRAAWRGELRERLHLPA
>NC_017093|256658:289350|272163_273297_-|WP_014440373.1|capsid|DBSCAN-SWA
MAVDPDKLTEIIRATVDLYRAGEHGLLRLVTRYLATGIDTPGWAIERLAALGQLRRAGQDILDSISDELAETVLQAVANAYAAGGASVLEEIPTELSAGAAAGAAATAVVPRSAAMEALAQALVQDIGARHSNVLRHITDVYRRVVAEGTAASIAGGLTRREASQLTYARLVEQGVVSFVDARGRRWRMSSYVEMAIRTVTQRAAVQGQVDKQRRLGLPFVVVSNEAQECERCRPYEGRVLRIGSGPTGTIEVAHQTTGEPVTIDVRATLDDARSWGFQHPNCRHSVRSYLPGITRLPRQPTADPDGDAARQRQRAIERAIRRWKERELAALTPAAAAQARARVVLWQGQMRQHLAANPTLKRLSYREQIGAGSAPR
>NC_017093|256658:289350|287183_287420_-|WP_014440397.1|DBSCAN-SWA
MHEHDLGFALNLARFDELTGHRGWKTDQQRAAGIGVSHTTLGRIRRGHIKPGTRFIAAATTALNTNVEYLFERNEATT
>NC_017093|256658:289350|276252_276741_-|WP_014440376.1|DBSCAN-SWA
MAGGHPPITDTERQRVAELHAEGLSRNAIAELLGRSGRTVSKICAEHDPPLTFERTRTAAATAAKKADGAARRAQLQVDLLENAQRLAGQMFAPSKIWNFGGKENDYNERTLDEPPFRDKQAIALSIKALADTAMKLADYDRTDVATSGIDAWLQHMTGDGD
>NC_017093|256658:289350|286210_286915_-|WP_014440395.1|DBSCAN-SWA
MTYQPPANASLWQVFLADEEGFVTTVEKALDEYGPESHVEVSIRRLSALPHLQAADNLWSLPGRPKHEADIAVEWKLDLVDDIGETDHITAQLNAAHAMAAGLNGALANQGEWNRSTELAAALHNLGDKLATFDGALPSGLYFHVLYGHAGTAEASATLIQNVDALGAHLLGKVGERKSDSTGYDDYKARGFIGPLTITAYGYVVRPAEEDPRILLARIAELQAEVAAARGGAA
>NC_017093|256658:289350|278553_278907_-|WP_014440381.1|DBSCAN-SWA
MTVSPATQAARQWATDHGHPQPDDRMLQAYEDNRPGSIRVPSTTSLGTALREIRHLHGLTLQQLADKTGINLQQLGEYERGRTMPSAVNLLKIIAAYEYKLALVAPQKQSGPNGDVA
>NC_017093|256658:289350|281024_281876_-|WP_014440387.1|DBSCAN-SWA
MARIRTIKPEFFTSLAIASLTLEARLTFIGLWTHVDDEGRCVDDARLIKAAVWPLDDRLSSDVELDLKALSESSLITRYTVGARSFLAITNWNEHQRINRPTRSKIPAPPPAETAPASPRYAPPPAETTPHSEPSHSPHAPLAEDSLAERNREQGTGNRENPAARVREDDPAGTPGRAEQIVQAWMTACTRRPPSRVVDAIGREVAQLLRDDIDPSDIQRALEYWQGRGMHPTSLPSVVNQVMNARPQGNVVALSGHTPRPSTTDQRVGAALELAAKYAQEDQ
>NC_017093|256658:289350|264594_265353_-|WP_014440364.1|DBSCAN-SWA
MAATPTTRVTALARRYRIDLNTGTWEARSWQELIGKQEVTLVEEIRTEADETHEDNGFYRETGTGVSWRIEAKIFFSKNAAGTAVHPVHRFLRDKYEAGKQATHLGEFAVRWYDKEGLDDGNSKEGTVFVKAFPPDGGGPEALDIVSLVLQGQGPQSVIDNPNADMTPVVTSLSPAAGGTAAGGLVNIYGGHFTGTTAVSFGGTAAPNFTVIHDGHIVATKPALTAGSKDVTVTTPAGTAETAGTTNDFVVS
>NC_017093|256658:289350|256890_257130_+|WP_157434704.1|DBSCAN-SWA
MNIDAPNFVVHVFDNQGMGMQNGTLDQATNRWIQDEADKHYNGDWGRAAAAILEAAHARAAHPEDQWAELDSRVKSRAK
>NC_017093|256658:289350|261908_263849_-|WP_014440361.1|tail|DBSCAN-SWA
MALKLGELVTYLRADDTALARGLASAQDKLQAAGEKAREYGPLIGGALAAGIGAGLVGALDADKAKAKLSAQLGGDAQYAADMGEIAGNVYGRGFGESLEAVNETLRGVLGSGLLDEDATNAEIESVTLKAQALADTFGQDVTQTARAAGQMVRTGLAKDSAEAFDILTRGFQQTGDHAGDLLDTFSEYSVQFQKMGIDGTTATGLLSQGLKAGARDADSVADAVKEFSLRAVDGSKTTSDALATLGLNADTVASGIAAGGPKAQAAFQMVLDKLRELGPESTTTQQAIQGLFGGPGENLGGALLALDLDTAAKSMGDVSGAADKMGETLEQSASQRLESFKRSAQAALVEKIGQAIPYIESLVGWIDRHSAVVGPAAAVLGTLALVIGTVIGVVKLWTIAQTALNLVLSMNPIGLVVLAIAALVAGIVLIASQTDIFSKMWKAAWGGIKSAASAVGSWFRDTLWQKWILGAWNGIINKGNQALDWFQALPGRLRSALSGAFDGLKSAFRSAINWVIGRWNNFSLTLGGGSILGMGIPSVTLNTPNIPMLAKGAVVPKTRGGRLTIVGEGREDEAVMPLSKLNNLVREARQDGTDRNGQPIEVHVYLGTREIEDLVDVRIKKSNAKTARKAGPRTKMVPQPTGRRR
>NC_017093|256658:289350|277772_278360_-|WP_014440380.1|DBSCAN-SWA
MTNQHHQLRASAALHTLEAALAALDDRVDDEYRAIRAEQAARYEPLKSPTFGRRHALGGHGDPTGDAAGTVGTTRPNRYAELRTEVQEQLLNVSRHVPRTGYVAHPVRDLEAAIPAMSPRAADRARLWFDRIDGRIRRQLRIAHDRQLVPRIPCPDCDTTGLIMRLSPPLDARVIECTTCGSAWPRSEVLGGVSA
>NC_017093|256658:289350|288129_289350_+|WP_014440399.1|integrase|DBSCAN-SWA
MWIEKHGPNWRIREEIAGRKTTLKSGFPTKTSAKAAMNAMNTDRARGDFINPQDGKVTLAQFVNDFWPGHETGLKPSSRRTQGSNLRVHVLPQLGLYRLDQIDTLVVTRFVHRLVNGDPDPVDGPPRKPLSPGSVRNVYGVLHTILGAATKARMIPFNPAIGVKMPPREHHEMKFCTPIEIERLLAACTGDDAHWRPLVMLLVTTGLRYGEAHALQVGKVDLFAGTVQVTRTAYEASGGRFVYTTPKTRSSRRTVRIPQELVLELAPLLAGKASDALVFTMPDGKPITGTFRKGTWKRITSRAGLTGLRLHDLRHTVASLLISANVPLTAIQRMLGHTSIKMTSDLYGHLMPEVNESIVDTLTEVLKRGSRRGGTTGIPAWPVEGERGGNLGGAWGIPALPNPAES
>NC_017093|256658:289350|258733_259270_-|WP_014440357.1|DBSCAN-SWA
MVDSTPIYGLPYQEDDDPPNGPLLSQSLAEAAEAAIRDVGRVVGYYSNTGTVQTVTTAGQTICTAATALRPGWAYDVTVRSQVSTSAALDFLPQIRRPDSSILVDYGRQGLPATGARFYEFRCSFRTAPTFTAATVGIVFRGTVSAGTAAFKGFASGPFEMVVRQAGAYDDCPGAPTY
>NC_017093|256658:289350|257862_258720_-|WP_014440356.1|DBSCAN-SWA
MADWMLVPCLVKLRDEFNSVAPRRDKGADGAIGDSSHTSSSDHTPDEDSDVLRDHDADDKNEVHAVDVDSDGPWPDGSGREAGGWFDRRIQHIAAQERIEYASPDVYGRLQYIIWRGRIISRSWGWSEWRTYSGASKHFDHAHISARYLTRTESDTRPWGVEEDDVTPEQLRAAVKAELKDALPDFAKAVGDLKVNVNPGTGKTPNWQRWSNVDAYGSPERARILAAIGALAKQVAALGGKDLVDEDAIVDAVLAGLTPERIAAGIPDGIAQDVVDALGERLAAA
>NC_017093|256658:289350|277545_277776_-|WP_014440379.1|DBSCAN-SWA
MILVDGELWGTAREIADQLGHGVTIRAVRYWASDQGLRKARIADGHGRPQVRYPLGQASRIELEMRDRGSVRGRRS
>NC_017093|256658:289350|270819_271239_-|WP_051042364.1|DBSCAN-SWA
MERLRANQQQHTAQLRAASVSQQAWALAPQLGVNPQALVGSLAWQQAAAQLDPAAADYAQRLQWTIQGVLAANPWMAATPANPAPGQPVPPNPPAPPAPTVPPAGPARSGGDFNGAPAAGAQQQIGPGIDRLRHAYSQT
>NC_017093|256658:289350|264016_264598_-|WP_063711126.1|DBSCAN-SWA
MMAKLSGLREYFNPELTLAVPDRHGVEREYVIPPASAELGLWCQMLAEVTGRLRTATAPEELQEVFDSIENELPQLGKGIRTLEQRTLSTAYDLMVADGVLHEHIKFCGRVAYLWIVRDEDEAERYWKSGGRPGEAPGPANRAERRAAGRTNTAAAAETPKPGSSSTTRSRNGSSRNRRARGGRGQRSSNSGT
>NC_017093|256658:289350|285992_286214_-|WP_014440394.1|DBSCAN-SWA
MIRADVLAAIILTALLVAIAISVLMVLAYEYRRRWTITNRRLDRVLREQREIAELREWYAAPAVTPEHERGDS
>NC_017093|256658:289350|269391_269793_-|WP_014440369.1|DBSCAN-SWA
MTTRAQSKAKQETTAQAAADQAVAEGHAPGEVPEATVAEGQVPGERQITAPGDGPADTTDPTERVSTVVVDGKTLAEAAQAGVGAVVGYVKTGEATPPGANPNRDTDKDRHEEYEVGGVRLRHNLETGKSERI
>NC_017093|256658:289350|257591_257819_-|WP_014440355.1|DBSCAN-SWA
MPAWLRNLTMITGLGAWLAVVIVSLVRGQLPDAILLGVPAGLVLALAPPAIGRSGGGSESPSPGASAEPRDGAQT
>NC_017093|256658:289350|265806_266160_-|WP_014440366.1|DBSCAN-SWA
MADEPYELNWSGDDVMAALRGASIDGLELAAEHLLQVSSELAPLEEGDLARSGEVSSDRGEQTVAVSYDRPYAVRQHEDMTLRHDAGKQAKYLEDPMNDEQETMLALIASRPRGLLG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014440353.1|256658_256898_-|holin	holin	A0A0K1Y5A3	Streptomyces_phage	3.4e-05	43.6
WP_157434704.1|256890_257130_+	hypothetical protein	NA	NA	NA	NA
WP_014440354.1|257131_257476_-	hypothetical protein	NA	NA	NA	NA
WP_014440355.1|257591_257819_-	hypothetical protein	NA	NA	NA	NA
WP_014440356.1|257862_258720_-	hypothetical protein	NA	NA	NA	NA
WP_014440357.1|258733_259270_-	hypothetical protein	NA	NA	NA	NA
WP_014440358.1|259280_259994_-	hypothetical protein	NA	NA	NA	NA
WP_014440359.1|259993_261118_-	DUF5047 domain-containing protein	Q6VY40	Streptomyces_phage	3.4e-39	34.4
WP_014440360.1|261114_261912_-	hypothetical protein	NA	NA	NA	NA
WP_014440361.1|261908_263849_-|tail	phage tail tape measure protein	A0A1B3B020	Gordonia_phage	3.3e-74	40.7
WP_063711126.1|264016_264598_-	hypothetical protein	NA	NA	NA	NA
WP_014440364.1|264594_265353_-	IPT/TIG domain-containing protein	NA	NA	NA	NA
WP_014440365.1|265366_265810_-	hypothetical protein	NA	NA	NA	NA
WP_014440366.1|265806_266160_-	hypothetical protein	A0A1J0MCM9	Streptomyces_phage	2.2e-21	49.5
WP_014440367.1|266163_266508_-	hypothetical protein	K4I2V6	Streptomyces_phage	2.3e-07	38.0
WP_014440368.1|266511_269376_-	fibronectin type III domain-containing protein	NA	NA	NA	NA
WP_014440369.1|269391_269793_-	hypothetical protein	NA	NA	NA	NA
WP_014440370.1|269833_270802_-	hypothetical protein	A0A2H5BLW0	Streptomyces_phage	2.4e-118	69.5
WP_051042364.1|270819_271239_-	hypothetical protein	NA	NA	NA	NA
WP_107088759.1|271767_272163_+	hypothetical protein	NA	NA	NA	NA
WP_014440373.1|272163_273297_-|capsid	phage minor capsid protein	A0A1V0E608	Streptomyces_phage	6.6e-67	40.1
WP_014440374.1|273300_274884_-|capsid	phage capsid protein	A0A1J0MCN7	Streptomyces_phage	1.2e-93	41.6
WP_107088760.1|274960_276256_-|terminase	PBSX family phage terminase large subunit	A0A1J0MC16	Streptomyces_phage	1.9e-89	42.5
WP_014440376.1|276252_276741_-	helix-turn-helix domain-containing protein	K4I306	Streptomyces_phage	7.4e-23	43.7
WP_014440377.1|276787_277042_+	DUF1298 domain-containing protein	NA	NA	NA	NA
WP_014440378.1|277128_277314_+	hypothetical protein	NA	NA	NA	NA
WP_014440379.1|277545_277776_-	hypothetical protein	NA	NA	NA	NA
WP_014440380.1|277772_278360_-	hypothetical protein	NA	NA	NA	NA
WP_014440381.1|278553_278907_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014440383.1|279073_279301_-	hypothetical protein	NA	NA	NA	NA
WP_051042365.1|279293_279683_-	hypothetical protein	A0A140G6H3	Arthrobacter_phage	3.3e-18	49.1
WP_014440386.1|280575_281028_-	hypothetical protein	NA	NA	NA	NA
WP_014440387.1|281024_281876_-	hypothetical protein	A0A1J0MCP9	Streptomyces_phage	5.9e-44	42.4
WP_041829497.1|282188_282410_-	hypothetical protein	NA	NA	NA	NA
WP_014440390.1|282406_284215_-	DEAD/DEAH box helicase	A0A126DN25	Acinetobacter_phage	1.6e-59	34.3
WP_014440391.1|284211_285456_-	hypothetical protein	A0A2P1JRI8	Mycobacterium_phage	5.0e-76	46.5
WP_014440392.1|285452_285713_-	hypothetical protein	NA	NA	NA	NA
WP_014440393.1|285705_285993_-	hypothetical protein	NA	NA	NA	NA
WP_014440394.1|285992_286214_-	hypothetical protein	NA	NA	NA	NA
WP_014440395.1|286210_286915_-	hypothetical protein	NA	NA	NA	NA
WP_014440396.1|286992_287184_-	hypothetical protein	NA	NA	NA	NA
WP_014440397.1|287183_287420_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
287562:287577	attL	NA	NA	NA	NA
WP_172666557.1|287637_288054_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014440399.1|288129_289350_+|integrase	site-specific integrase	Q859H7	Micromonospora_phage	1.4e-83	46.4
290640:290655	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_017093|8524219:8531768|DBSCAN-SWA
AATGACCTACGTGGTCAACGGCATGCCAGCCGGCCAACTGCAGGGCGCTGTCTGGCAGAAGAGCCGTCGCAGCAACCCGAGTGGCAACTGCGTGGAGTGCGCTGTCCTGCCCGGCGGTGACGTCGCCGTGCGCAACTCCCGGGACCCGGAGGGCGCTGCGCTGATCTACACGCGCGCCGAGATCGAGGCGTTCCTCGGTGGCGTTCGCGACGGAGACTTCGACAACCTCGTCGCCTGACGCGCGGTTCACCGACACAACTGAACTGGGGCTGATCTTTCACACGGTCCGGTCGCTGTGCGGCCGGACCGTGCCGTTTTCCGGCCTTCCGGCCCGCGCCCGGCCGGGCCGTTTTTCGGCCTTCCGGCCCGCGCCCGGCCGTGCCGTTTCTGGCCTGCGCTCGGCCGTCAGGCCGGGCGGCCCACCTCGTGCAGCAGCTTGCCGAGGATCTCCGGCGTGTGGTTCGGCGGCTCGGCGTCGATGCAGACCCGCTCCATCGCCATCGCGTACTGATCGACGTCCTCGCGCTTGTCCAGGTAGATCGCGCTGGTCAGCTGCTCCACGTAGACCACGTCGGGAAGCTCCGGCTCGGGGAACCGCAGGATCGCGAACGGACCACCGGCCGCGGCGTGCCCACCGGCGTGGAACGGGATGATCTGCAGCCGCACGTTCGGCATCTTCGACGCCTCGATCAGCGCCTCGATCTGCTGGCGCATCACATCGACGCCGCCGATCGGCCGGCGCAGCACCGCCTCGTCGATCACCGCCCAGAGCTGCGGACCGCCCGACCGGGTGAGAATCTGCTGCCGATGACGCCGCACCTCGACGCGCCGGTCGATCTCCTCGACGCTGGCGCCGGCGTGACCCAGCATGATCACGGCACGCGCGTACTCCGGCGTCTGCAACAGGCCCGGGACGAATTGGATCTCATAGGTACGGATCAGCGAAGCCGCCGCTTCCAACCCGAGGTACGCCTGGAACCAGCCCGGAAGGATGTCGCTGAAGTGCTGCCACCAGCCCGGATTGTTCGCCTGCCGGGCCAGCCCGATCAGGGCCTCGCGCTCGTTGGGGTCGACCACGCCGTACATGGTCAAGAGGTCTGTGACGTCGCGTTCCTTGAAGCTGACCCGGCCCAGCTCCATCCGGCTGATCTTGGAACCGGACGCCCGGATCTCGTAGCCCGCCGCCTCGCGGCTGATGCCCTTGGACTCCCGCAGCTTGCGGAGCTGGGAGCCGAGCAGAATGCGGAGAACGGTGGGGCCACCGCCCGGCGCCTCCTCCTGCGAACCCGCGCTCACCTGACTCCTCGTCGCCGCCTTGTGACTGCCTGGCACAGCCACATGCATCCTAAAGCGGAGATCGTCCGCTGCGAAACCACGTCCCCGCCTTGCACGCCGCCATCTGCGCGATGCGGATGCACGTGCATCCGGCCTTGCGAACGCACTTGATGACGAGCATGATAGCTGACAGACACGTACCCGTTCGATAACACAGCGTGCCGAAAAGTCAGACTGCTCGGCCGATGTGGTCCCCGACACCCGCCTCAGTGAGAATGGTGGAGGCACACACATGTCGAAGACGCTGGCGTCCACGCCGACAGTCGCCCCGCCACAGCGTGACCCGGCGGATGTCGCCCCGGCCGAGAGCTACCGTCCCGCCGATCCGGTGTGGGTCTATCGCGACGGCTGGCGCGCCGGCGTCATCGAGGCGTCCTCGCCCCGAGCGGTCACCGTGACGTACCGGCCGCTCGGCCACCTGGGGACCGGGGTCGACACGTTCACCGCGCCGTATGTGACGTCCCGCTTCGACAGCGATCCCACTCTCGACCAGCGCGGCCTGCGCCTGGTGCGCCGCACCCCGCTGAACCGGGGACCGCTGGCATGACGGGCGCGGTGACGGTCTCCGCCATCGTCGGCCTGCTGAGCCTCTTCTCCGGCGTGGCCCTCGGGTGGTACCTACGACGTACCAACGACTGGTGCCCGACCTGCGGCGAGCAGCTGACCTGCCACGGCACCTGCCAAGTCAGCGCGGTGCGGGCGTCACTGTAGCTTTATATTTATGACAGCGGCTGACGAAAAGCGCCTGACGTGCGTGAACAGGAGCGCCGCTCTCTCCCGGGCCTTCGAGTTCCTGGGCCGCCGGTGGAACGGCGCCGTCCTCGGCAAACTCCGCGACGGGCCGCTCGGCTTCCGGGAGATCTCCCGTGAGATCGACGGCATCAGCGACTCGGTCCTGTCGAACCGATTGTCCTCTCTGGTCACCGCGGGACTGATCGTCCGCGTCGTCGACGCCGGCCCGCCGGTGTCGGTCTCCTACAGCTTGACCGATTCCGGTCGCGCGCTGATGCCCGCGCTCGACGAGATCGCCGTCTGGGCCGATCAGCACCTCACTCCGTGATCATCTTCACCCGCCGATCAGTGGCTTTCTCTGCCACAGCAACTACTTTTTTAGAAGTGGATACTCTTTCTGAAGCGGGTCCGGTCTCTCGTGGTCTGAGCGCCGAGGGGCGTGCCCTGCTGTTCACGGACGCACGCACCGCGTCGGCGTTCGCGCCGACCCCGGTCACCGACGCGGAGCTCGCCGAACTCTGGGATCTGGCGAAATGGCCGCCGACGGCCGCGAACACCCAGCCGTTGCGGGTGCTGTTCGTGCGTACCCAGGAAGGCAAGGCCCGCCTGATCCCCCACCTCGCGGAAGGCAACCGGCCGAAGTCGCAGAGCGCGCCGGTCGTCGCGGTGCTGGCGCTCGACACGTCGTTCCACGAGCACGTGCCGCAGGTGTTCCCGCACAACCCCGGCCTCAAGGACGTGTACGAGGCGAACCGCGACCTGCGCATCACCAACGGCACGTTCAGTGCGGCGCTGCAGGTCGGGTACTTCGTCCTGGCGGCCCGCGCGATCGGCCTCGTCGCAGGTCCGATGACCGGTTTCGACAAGGCCGGCGTGGATGCTGAATTCTTCCCGGACGGGCGCTTCGCGTCGCTTGCGGTGGTGAACCTCGGACACCCGGGTGAGAAGGCGTGGCGGGACCGGCTGCCTCGGTTGTCGCCGGAGACGACTGTGCAGTGGGCCTGAGCCGGTGGTAGAAGCGGCCCGGCGGTTTCCTCTTTGCCGCCGGGCCGCTTCCTCTTACTTCCAGGTCTGCCCGGCCTACTTCCAGGTGTCGCCGGTTAGGCGCTCGTAGACCTCGATGTAGCGGTTGCGCGTCGCCTCAACCACCTCGTCGGGGATCTCCGGACCCGGCGCCGTCCGATCCCAATCAGTCAGCTGACCGGACCAGTCCCGCAGGAACTGCTTGTCCAGGTACCGCGGCACACTGCCCGGCTTCCACTCGTCCGCACTCCAGAACCGGGACGAGTCGGGCGTGAGCAGCTCGTCGCCCAGCTTCAGCGTTCCATCCTTGGCCCGCCCCACCTCGATCTTGGTGTCGGCCAGGAGCATCCCCTTGCCGGCCGCGACCTCGGAGCCCCGGCGGTAGATCTCCAGCGTGACCCGCCGCAGCTCCTCGGCCAGCTCTCGGCCGACCCGCCCCACCGTCTCGTCGAACGTCAAAGGCGCGTCGTGTCCGCCACCGACGGGCTCCTTGGTGCTCGGCGTGAAGATCGGCTCAGGCAACTGGGACGACTCCACCAGCCCGGCCGGCAGCGGGTTGCCGGAGATCTGCCCGTCCCGCTGGTAATCCCGCAGCCCGGAGCCCGCCAGGTAGCCACGCGCGATGCACTCCACCATGACCATCTCAAGGCGCTCGCAGCGGATCGCCCGCCCCTGCCACTCGGCCGGCACATCGGTCACCGAGATGACGTGATTCGGAATCACGTCAGCGAGCTGATCGAACCACCAGAGCGAGAGCTGGGTGAGGATCTTCCCCTTGTCCGGGATCGGCGTGGGCAGGATGACGTCATAGATCGAGATCCGGTCCGAGGCGACCAGGAGCAGGTCCTCCCCGTCCGCATAGACGTCCCGAACCTTGCCGGAGTGCAGCAGTTCCACTTGTTCCCCTCGGTCGTACCGTCACTCTCGCAGCTACCGTATCGAGTCGCGCTCAGCCTCTGCGCACCTATGCCATGCGTGGCCAGCAAGCCCTCGCTCGGGCAACCCGCCCAAACCAACAAGACCCAACCGTGGCCTCTGCGACCACACAGCACACCAAACAGGCTTCCATAACTTCTTTCCGCAGCAGAAACCTGGCTTGATTGCGCAAGAGACGAAAACCATCCGCTAGCAGCGCAGTCAAACTCCCGCGGGAGGCGGTCGATAAAAAGATCATTCCCCTGAAAATCTCATATGACCTAAACCTCATCATCAACAACTGGCTAGAACAAGTCACCCATTTGACGGACACACTGATGGGTGCCATCGAATATTCTCAGGCAGAGAAACAGGGTCAGGTACAGAACATCTGCCACCTCAACACCCAGCAGCGCCGCGATGCTGGGCCGCGAGATAAGACATCTGGAAACCGGGGTATTCCTTCTCGCGAATCTGAGTCTTTGTTTATGGTGGATGCAGTCACCGCAGATGGCCGGCGGATAGATACTAGGAAGCCCACCTGACAGCAGCCCAGAGGGCACAGGTGATGGCAACTCCTCCCGGCAGGCAACCGGGGACGTTCGCCCGAGGCGCACCCGACCGTATGGATACCATCCGCCTCGGACGGTCACCTGTTCGCACCGTAACGCTTGAGGCGACACTTCGTTACAAGGCGTAGCCGGCTGCCACGAAGGGTAGGCATCACGTGCGGTATATGATTGGATCGGTCACAGACTGGCGTTACGCCTCGTCAGTTCGCCATTGCAGATATAAGCTGCAACGATGATCGGCGATGGAGGGCGCATGGAAACCGAGGCTATCAATGCCGCAGAATTCTTCGCCGGGATTGGCCTTGTACGTACGGCTTTGGAGCCTCTTGGAGTCAAGGTCGTGTGGGCCAACGACATCAAGCAAGCGAAATACGAAGCGTATCGCGCGAACTATCCAGATGCAGAAAAGCATTTCAAGGTTGATGATATCCGCAATGTGGTAGGCGATCAATTGAAGACGTTGTCAAGACTCGAGCTGGCAACGAGCAGCTTCCCCTGCATCGACCTTTCCCTCGCAGGCAACCGGCGTGGATTGGTGGGAGAGCAGTCTGGCATGTTCTGGCAATTCGCGCGCGTTCTTGACGAGATGTCAGAGGAAATCCGTCCTCGCGTAGTGCTGCTCGAAAATGTCCATGGGTTCGCTACCAGCCATGGCGGGCAGGACTTGACAGATGCACTCGCACGATTGTCACAACTAGGGTACTCGCTCGACGTGCTCGCCATCGACGCTAAGCACTTCGTTCCGCAGTCGCGGCCTCGTATGTTCATCGTAGGCGTGCTGCCAGCAGATTTGCCAAATAATGCGCACGTCGGCGTGCCAGTGGTTAGCGACGTTCGGCCGGCCTGGGTCACAGCGATCCACGCCAAGAACCAAGACAAGATCAAGATGCACTACCTCGACCTACCCGACCTGCCGGTAGGGCCGACAGATTTGAGCGGCGTGATCGAGTATGGAGCCCCCGAGAGTCTCTGGTGGGATCAGCAACGCGTCAAGGCGTTTGTGGATTCATTGAGCGACGGCCAAAGGCTCCGTTTCGAAGCGTTACGAACCTCAGATGCCCTCTCCTATCGGACTGCCTACCGGCGCACTCGGCAAGGCGTATCGATGTGGGAGCTTCGACGCGATGCCATCGCCGGCTGCCTACGAACGACCGGAGGAGGATCGAGCAAGCAGGCGCTAGTTGAACTTGGGTTCGGCCGTGAGCCTCGTGTACGATGGATGACCCCTCGCGAGTACGCTAACTTGATGGGTGCAACCGAATATAGACTCATCGCTGGAACGCCAAACCAGCAACTGTTCGGTTTTGGTGATGCCGTTGTCGTGGACGTCGTTCGATGGATTGGCAAGCATTATCTGTTGCCCGTATTGCGACCAGACAATAAGGCTGGAAACTAATTGCCCGGCTTGTGCAGGGAAAACCAACCCCGCGCTATCCACGACAGCACCAATCCCGTGGCAGGGCCCTCAGCAGCATTGCTTCTTCGAGACCCGATAAGGCGTCATGGCTCCAAATAAATTGCCAGCGGTTCCGCCCCCGTCTCGCGCCACGAAGTCAATGAAGGCGAATCGGAGCTCGGGCACTAAGCCCGAGCTTGCCCTACGGCGGGAGCTGTTCCGGCAAGGTCTTCGATATCGCGTGGGCCTACAAATTTCGTTGCGTGATAGAAAAGTACGCCCTGACGTCGTTTTCCCTCGACGCAGGGTTGCAGTATTTTTAGACGGCTGTTTTTGGCATGGCTGTCCCATACATGGGAGAATGCCCGCCGACCCAACCGGATATTGGCACGCCAAGATCGAAGGAAACAGAAATCGCGATGCGGTCGTAGACATTCAGTTGAATGACGCGGGGTGGGCAGTTATACGAGTATGGGAGCATGAGTCGGCAACCGAGGGTGCCGCCCGCATCAAATCCCTAGTCCTTTGCCGTTAAGAGTTAAGAACGCACTTGAACGGCCAGGGATAGCCTTCACCTCGAGGCAAGAAGGGCACCCTTCCTTACGACACTCTTCAAGGATCGTGTGTGGACGGCTGGCTGGACGACAGCCATGGTGGGCCAAGGCTTGCGCATCGTGCAGGTCCTTCCCACGCAGAGAACCTCTCATACAGCCCGCCTTCCATGCTTCGCCATTGCCCCGTATACTGGCCAGCCGATGAAATAGATGACTCGGATTTCAGAGGTGTGTAAAGTGGCCAGCCGCGGCATCGCTTCTTACAATCAGCCGGATCACCAACTGCCATCACGGGCATCGCTGCCGACTGCCTTTGTCCAAGGGTTCCGCCGCCTATTGAAAAGCGCGATGAGCACCGTCGACCCGGCAAGCAACAAGCGGCTGGGGAACTGTATTGGCGTATACGCCTTCTACGACTACGACGGCGAGCCTATTTATGTCGGTCAAACCTGGCTGAAGTTCACCGACCGAATCGGCCGACACCTAACCAGTCAGCGAAGCGATACTCTGGCATATCGGATCCTCGATCCTTTTGAGGTTGCCGCAGTGGAGTTGTGGCCAACAGAGTATCTGCGTGACGATCCAAACAAGCAAGAAAAACTTAACGAAATCGAGTTCTCCGCATACCGTAGAGCGATTGATGACTCGAAGTACAAAGCGATTCTCAATGAGAAGATTCCGCCCCCGTCTGACTTCGTAAGACTGCCACCCTCTTATCGTTTCAACTTGATCCCCGGAGAATTGCGGGAAGAACGCGAACATCCAGACGTACGTATCGCCCGTCGCGCTGAGACCTTGTCCAGAGTGGCGGCCGTTGCCCATGAACGCGGCGAAGTTTCGGCCGGTTTACGCCGCGTCATCGTTATCCAAGCAGTCCGCTTAGCTGACTTGGCCGCGGCCCGCTTGGCGTACGCAGAAGGCCGGCGCAGACCCTCTCCGGGCGCAATCAACGTACAAGAGCTAGTTGGAAACGTTCTCGAAGACTCCGACTCCGACTCGGATGAGGTCAACGACGACTTCTGA

Protein sequences of DBSCAN-SWA_2

>NC_017093|8524219:8531768|8530297_8530726_+|WP_083888774.1|DBSCAN-SWA
MAPNKLPAVPPPSRATKSMKANRSSGTKPELALRRELFRQGLRYRVGLQISLRDRKVRPDVVFPRRRVAVFLDGCFWHGCPIHGRMPADPTGYWHAKIEGNRNRDAVVDIQLNDAGWAVIRVWEHESATEGAARIKSLVLCR
>NC_017093|8524219:8531768|8525785_8526100_+|WP_014447993.1|DBSCAN-SWA
MSKTLASTPTVAPPQRDPADVAPAESYRPADPVWVYRDGWRAGVIEASSPRAVTVTYRPLGHLGTGVDTFTAPYVTSRFDSDPTLDQRGLRLVRRTPLNRGPLA
>NC_017093|8524219:8531768|8527365_8528205_-|WP_014447997.1|DBSCAN-SWA
MELLHSGKVRDVYADGEDLLLVASDRISIYDVILPTPIPDKGKILTQLSLWWFDQLADVIPNHVISVTDVPAEWQGRAIRCERLEMVMVECIARGYLAGSGLRDYQRDGQISGNPLPAGLVESSQLPEPIFTPSTKEPVGGGHDAPLTFDETVGRVGRELAEELRRVTLEIYRRGSEVAAGKGMLLADTKIEVGRAKDGTLKLGDELLTPDSSRFWSADEWKPGSVPRYLDKQFLRDWSGQLTDWDRTAPGPEIPDEVVEATRNRYIEVYERLTGDTWK
>NC_017093|8524219:8531768|8524219_8524456_+|WP_014447991.1|DBSCAN-SWA
MTYVVNGMPAGQLQGAVWQKSRRSNPSGNCVECAVLPGGDVAVRNSRDPEGAALIYTRAEIEAFLGGVRDGDFDNLVA
>NC_017093|8524219:8531768|8526274_8526613_+|WP_014447995.1|DBSCAN-SWA
MTAADEKRLTCVNRSAALSRAFEFLGRRWNGAVLGKLRDGPLGFREISREIDGISDSVLSNRLSSLVTAGLIVRVVDAGPPVSVSYSLTDSGRALMPALDEIAVWADQHLTP
>NC_017093|8524219:8531768|8526669_8527290_+|WP_014447996.1|DBSCAN-SWA
MDTLSEAGPVSRGLSAEGRALLFTDARTASAFAPTPVTDAELAELWDLAKWPPTAANTQPLRVLFVRTQEGKARLIPHLAEGNRPKSQSAPVVAVLALDTSFHEHVPQVFPHNPGLKDVYEANRDLRITNGTFSAALQVGYFVLAARAIGLVAGPMTGFDKAGVDAEFFPDGRFASLAVVNLGHPGEKAWRDRLPRLSPETTVQWA
>NC_017093|8524219:8531768|8530982_8531768_+|WP_083888775.1|DBSCAN-SWA
MASRGIASYNQPDHQLPSRASLPTAFVQGFRRLLKSAMSTVDPASNKRLGNCIGVYAFYDYDGEPIYVGQTWLKFTDRIGRHLTSQRSDTLAYRILDPFEVAAVELWPTEYLRDDPNKQEKLNEIEFSAYRRAIDDSKYKAILNEKIPPPSDFVRLPPSYRFNLIPGELREEREHPDVRIARRAETLSRVAAVAHERGEVSAGLRRVIVIQAVRLADLAAARLAYAEGRRRPSPGAINVQELVGNVLEDSDSDSDEVNDDF
>NC_017093|8524219:8531768|8524623_8525562_-|WP_172666651.1|DBSCAN-SWA
MHVAVPGSHKAATRSQVSAGSQEEAPGGGPTVLRILLGSQLRKLRESKGISREAAGYEIRASGSKISRMELGRVSFKERDVTDLLTMYGVVDPNEREALIGLARQANNPGWWQHFSDILPGWFQAYLGLEAAASLIRTYEIQFVPGLLQTPEYARAVIMLGHAGASVEEIDRRVEVRRHRQQILTRSGGPQLWAVIDEAVLRRPIGGVDVMRQQIEALIEASKMPNVRLQIIPFHAGGHAAAGGPFAILRFPEPELPDVVYVEQLTSAIYLDKREDVDQYAMAMERVCIDAEPPNHTPEILGKLLHEVGRPA
>NC_017093|8524219:8531768|8529048_8530191_+|WP_157435562.1|DBSCAN-SWA
METEAINAAEFFAGIGLVRTALEPLGVKVVWANDIKQAKYEAYRANYPDAEKHFKVDDIRNVVGDQLKTLSRLELATSSFPCIDLSLAGNRRGLVGEQSGMFWQFARVLDEMSEEIRPRVVLLENVHGFATSHGGQDLTDALARLSQLGYSLDVLAIDAKHFVPQSRPRMFIVGVLPADLPNNAHVGVPVVSDVRPAWVTAIHAKNQDKIKMHYLDLPDLPVGPTDLSGVIEYGAPESLWWDQQRVKAFVDSLSDGQRLRFEALRTSDALSYRTAYRRTRQGVSMWELRRDAIAGCLRTTGGGSSKQALVELGFGREPRVRWMTPREYANLMGATEYRLIAGTPNQQLFGFGDAVVVDVVRWIGKHYLLPVLRPDNKAGN
>NC_017093|8524219:8531768|8526096_8526264_+|WP_014447994.1|DBSCAN-SWA
MTGAVTVSAIVGLLSLFSGVALGWYLRRTNDWCPTCGEQLTCHGTCQVSAVRASL

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014447991.1|8524219_8524456_+	DUF397 domain-containing protein	A0A1J0MC88	Streptomyces_phage	6.1e-07	40.7
WP_172666651.1|8524623_8525562_-	helix-turn-helix domain-containing protein	A0A1J0MBX1	Streptomyces_phage	2.6e-16	33.5
WP_014447993.1|8525785_8526100_+	hypothetical protein	NA	NA	NA	NA
WP_014447994.1|8526096_8526264_+	hypothetical protein	NA	NA	NA	NA
WP_014447995.1|8526274_8526613_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014447996.1|8526669_8527290_+	malonic semialdehyde reductase	NA	NA	NA	NA
WP_014447997.1|8527365_8528205_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	8.7e-40	36.1
WP_157435562.1|8529048_8530191_+	DNA (cytosine-5-)-methyltransferase	I6NLI4	Burkholderia_phage	1.1e-42	33.9
WP_083888774.1|8530297_8530726_+	very short patch repair endonuclease	V5UTF4	Oenococcus_phage	8.2e-10	34.2
WP_083888775.1|8530982_8531768_+	GIY-YIG nuclease family protein	I6NP88	Burkholderia_phage	3.7e-08	31.5