CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017067	Marinobacter hydrocarbonoclasticus ATCC 49840, complete genome	1 crisprs	WYL,DEDDh,cas3,DinG,RT,csa3	0	0	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_017067_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017067_1

3753133-3753235

Orphan

Consensus_repeat	Method
GCTTTCCAAAACACGCTGTGAATACATCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017067_1

>merge|NC_017067|1|3753133-3753235|CRISPRCasFinder
GCTTTCCAAAACACGCTGTGAATACATCCTTGTACGCTCCCTCATCGCTCGCCGCCCGCACACCGTGGGGTTGAGCTTTCCAAAACACGCCGTGAATACATCC

>NC_017067|1|1|3753133-3753235|CRISPRCasFinder
GCTTTCCAAAACACGCTGTGAATACATCC	TTGTACGCTCCCTCATCGCTCGCCGCCCGCACACCGTGGGGTTGA
GCTTTCCAAAACACGCCGTGAATACATCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_017067.1\|WP_014422953.1\|3737290_3737740_-\|DUF4124-domain-containing-protein	unknown	unknown	gnl\|CDD\|379230
NC_017067.1\|WP_011787131.1\|3758217_3758751_-\|type-VI-secretion-system-lipoprotein-TssJ	unknown	unknown	gnl\|CDD\|378947
NC_017067.1\|WP_014422961.1\|3751500_3753066_-\|sigma-54-interacting-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226350
NC_017067.1\|WP_041655168.1\|3753405_3756048_-\|type-VI-secretion-system-ATPase-TssH	unknown	unknown	gnl\|CDD\|274528
NC_017067.1\|WP_158011898.1\|3745787_3749372_-\|type-VI-secretion-system-membrane-subunit-TssM	unknown	unknown	gnl\|CDD\|274531
NC_017067.1\|WP_041655667.1\|3743560_3745684_-\|type-VI-secretion-system-tip-protein-VgrG	unknown	unknown	gnl\|CDD\|274542
NC_017067.1\|WP_041655666.1\|3743002_3743545_-\|DUF4123-domain-containing-protein	unknown	unknown	gnl\|CDD\|379225
NC_017067.1\|WP_041655166.1\|3750868_3751504_-\|type-VI-secretion-system-associated-protein-TagO	unknown	unknown	gnl\|CDD\|378637
NC_017067.1\|WP_014422963.1\|3756058_3756880_-\|DotU-family-type-IV/VI-secretion-system-protein	unknown	unknown	gnl\|CDD\|225986
NC_017067.1\|WP_011787136.1\|3763567_3765049_-\|type-VI-secretion-system-contractile-sheath-large-subunit	unknown	unknown	gnl\|CDD\|274538
NC_017067.1\|WP_014422959.1\|3749408_3750857_-\|type-VI-secretion-system-protein-TssA	unknown	unknown	gnl\|CDD\|379913
NC_017067.1\|WP_011787137.1\|3765110_3765608_-\|type-VI-secretion-system-contractile-sheath-small-subunit	unknown	unknown	gnl\|CDD\|377529
NC_017067.1\|WP_114435202.1\|3738922_3742963_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224117
NC_017067.1\|WP_014422966.1\|3760075_3761092_-\|type-VI-secretion-system-baseplate-subunit-TssG	unknown	unknown	gnl\|CDD\|274530
NC_017067.1\|WP_014422967.1\|3761055_3762828_-\|type-VI-secretion-system-baseplate-subunit-TssF	unknown	unknown	gnl\|CDD\|274541
NC_017067.1\|WP_014422964.1\|3756883_3758218_-\|type-VI-secretion-system-baseplate-subunit-TssK	unknown	unknown	gnl\|CDD\|226053
NC_017067.1\|WP_014422954.1\|3737877_3738933_-\|hypothetical-protein	unknown	unknown	unknown
NC_017067.1\|WP_014422969.1\|3763126_3763564_-\|type-VI-secretion-system-baseplate-subunit-TssE	unknown	unknown	gnl\|CDD\|274540
NC_017067.1\|WP_014422952.1\|3736169_3737264_+\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|223777
NC_017067.1\|WP_014422965.1\|3758747_3760058_-\|type-VI-secretion-system-associated-FHA-domain-protein-TagH	unknown	unknown	gnl\|CDD\|274537

Protein	Function_ID	Function_description	E-value
NC_017067.1\|WP_014422953.1\|3737290_3737740_-\|DUF4124-domain-containing-protein	gnl\|CDD\|379230	pfam13511, DUF4124, Domain of unknown function (DUF4124). This presumed domain is found in a variety of bacterial proteins. It is found associated at the N-terminus associated with other domains such as the SLT domain and glutaredoxin domains in some proteins. The function of this domain is unknown, but it may have an Ig-like fold.	6.05405e-13
NC_017067.1\|WP_014422961.1\|3751500_3753066_-\|sigma-54-interacting-transcriptional-regulator	gnl\|CDD\|226350	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms].	2.42399e-126
NC_017067.1\|WP_041655168.1\|3753405_3756048_-\|type-VI-secretion-system-ATPase-TssH	gnl\|CDD\|274528	TIGR03345, VI_ClpV1, type VI secretion ATPase, ClpV1 family. Members of this protein family are homologs of ClpB, an ATPase associated with chaperone-related functions. These ClpB homologs, designated ClpV1, are a key component of the bacterial pathogenicity-associated type VI secretion system. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NC_017067.1\|WP_158011898.1\|3745787_3749372_-\|type-VI-secretion-system-membrane-subunit-TssM	gnl\|CDD\|274531	TIGR03348, VI_IcmF, type VI secretion protein IcmF. Members of this protein family are IcmF homologs and tend to be associated with type VI secretion systems. [Cellular processes, Pathogenesis].	0
NC_017067.1\|WP_041655667.1\|3743560_3745684_-\|type-VI-secretion-system-tip-protein-VgrG	gnl\|CDD\|274542	TIGR03361, VI_Rhs_Vgr, type VI secretion system Vgr family protein. Members of this protein family belong to the Rhs element Vgr protein family (see TIGR01646), but furthermore all are found in genomes with type VI secretion loci. However, members of this protein family, although recognizably correlated to type VI secretion according the partial phylogenetic profiling algorithm, are often found far the type VI secretion locus.	0
NC_017067.1\|WP_041655666.1\|3743002_3743545_-\|DUF4123-domain-containing-protein	gnl\|CDD\|379225	pfam13503, DUF4123, Domain of unknown function (DUF4123). This presumed domain is functionally uncharacterized. It is about 120 amino acids in length and contains several conserved motifs that may be functionally important. This domain is sometimes associated with the FHA domain.	1.22154e-15
NC_017067.1\|WP_041655166.1\|3750868_3751504_-\|type-VI-secretion-system-associated-protein-TagO	gnl\|CDD\|378637	pfam11319, VasI, Type VI secretion system VasI, EvfG, VC_A0118. VasI is a family of Gram-negative proteins that form part of the pathogenicity apparatus for bacteria-to-bacteria attack. The exact function of this component is not known.	1.89217e-73
NC_017067.1\|WP_014422963.1\|3756058_3756880_-\|DotU-family-type-IV/VI-secretion-system-protein	gnl\|CDD\|225986	COG3455, COG3455, Type VI protein secretion system component VasF [Intracellular trafficking, secretion, and vesicular transport].	6.31963e-81
NC_017067.1\|WP_011787136.1\|3763567_3765049_-\|type-VI-secretion-system-contractile-sheath-large-subunit	gnl\|CDD\|274538	TIGR03355, VI_chp_2, type VI secretion protein, EvpB/VC_A0108 family. Work by Mougous, et al. (2006), describes IAHP-related loci as a type VI secretion system (). This protein family is associated with type VI secretion loci, although not treated explicitly by Mougous, et al. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NC_017067.1\|WP_014422959.1\|3749408_3750857_-\|type-VI-secretion-system-protein-TssA	gnl\|CDD\|379913	pfam16989, T6SS_VasJ, Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ. T6SS_VasJ is a family from Gram-negative bacteria that forms a component of the type VI pathogenic secretion system. In the case of the Escherichia coli RS218 strain UniProtKB:G8IRL4, EvfF,it represents expression of the full-length gene; whereas it is just the C-terminal part of EvfE, UniProtKB:G8IRL3. The N-terminal part of these sequences is in family ImpA_N, pfam06812.	1.56824e-96
NC_017067.1\|WP_011787137.1\|3765110_3765608_-\|type-VI-secretion-system-contractile-sheath-small-subunit	gnl\|CDD\|377529	pfam05591, T6SS_VipA, Type VI secretion system, VipA, VC_A0107 or Hcp2. VipA is a family of Gram-negative bacterial proteins that form part of the type VI pathogenic secretion system. Members have been variously defined as VC_A0107 family, Hcp2 and VipA, for ClpV-interacting proteins. VipB and VipA proteins interact very closely to form the shaft of the pathogenic penetrating needle system.	6.92053e-71
NC_017067.1\|WP_114435202.1\|3738922_3742963_-\|hypothetical-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	7.51403e-07
NC_017067.1\|WP_014422966.1\|3760075_3761092_-\|type-VI-secretion-system-baseplate-subunit-TssG	gnl\|CDD\|274530	TIGR03347, VI_chp_1, type VI secretion protein, VC_A0111 family. Work by Mougous, et al. (2006), describes IAHP-related loci as a type VI secretion system (). This protein family is associated with type VI secretion loci, although not treated explicitly by Mougous, et al. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	2.77479e-116
NC_017067.1\|WP_014422967.1\|3761055_3762828_-\|type-VI-secretion-system-baseplate-subunit-TssF	gnl\|CDD\|274541	TIGR03359, VI_chp_6, type VI secretion protein, VC_A0110 family. This protein family is associated with type VI secretion in a number of pathogenic bacteria. Mutation is associated with impaired virulence, such as impaired infection of plants by Rhizobium leguminosarum.	0
NC_017067.1\|WP_014422964.1\|3756883_3758218_-\|type-VI-secretion-system-baseplate-subunit-TssK	gnl\|CDD\|226053	COG3522, COG3522, Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport].	0
NC_017067.1\|WP_011787131.1\|3758217_3758751_-\|type-VI-secretion-system-lipoprotein-TssJ	gnl\|CDD\|378947	pfam12790, T6SS-SciN, Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113. One of the virulence mechanisms of E coli is the production of toxins which it produces from dedicated machineries called secretion systems. Seven secretion systems have been described, which assemble from 3 to up to more than 20 subunits. These secretion systems derive from or have co-evolved with bacterial organelles such as ABC transporters (type I), type IV pili (type 2), flagella (type 3), or conjugative machines (type IV). The type VI secretion system (T6SS) is present in most pathogens that have contact with animals, plants, or humans. SciN is a lipoprotein tethered to the outer membrane and expressed in the periplasm of E coli and is essential for T6S-dependent secretion of the Hcp-like SciD protein and for biofilm formation.	1.75962e-37
NC_017067.1\|WP_014422969.1\|3763126_3763564_-\|type-VI-secretion-system-baseplate-subunit-TssE	gnl\|CDD\|274540	TIGR03357, hypothetical_protein_Atu4338, type VI secretion system lysozyme-like protein. The description for Pfam family pfam04965 cites acidic lysozyme activity for some phage-encoded members. This family represents a different subgroup of the proteins from pfam04965, where all members are associated with bacterial type VI secretion system genomic contexts.	3.1706e-49
NC_017067.1\|WP_014422952.1\|3736169_3737264_+\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|223777	COG0705, COG0705, Membrane associated serine protease [Amino acid transport and metabolism].	1.45389e-33
NC_017067.1\|WP_014422965.1\|3758747_3760058_-\|type-VI-secretion-system-associated-FHA-domain-protein-TagH	gnl\|CDD\|274537	TIGR03354, VI_FHA, type VI secretion system FHA domain protein. Members of this protein family are FHA (forkhead-associated) domain-containing proteins that are part of type VI secretion loci in a considerable number of bacteria, most of which are known pathogens. Species include Pseudomonas aeruginosa PAO1, Aeromonas hydrophila, Yersinia pestis, Burkholderia mallei, etc. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	1.19743e-84

>NC_017067.1|WP_014422961.1|3751500_3753066_-|sigma-54-interacting-transcriptional-regulator
MQKELHTGIDLAVALIKQDTLPALLNTATRQLESAFGLSKCWALELDLSGRTLHCSKLDEAGEFDCNDFSHPFAHVLQTGQPRELTRAASYRLDHAGFQTLLELSGRPRSFWLEPLKGEDGRTLGMLVLCGDHPDWQGIVTQPLYSGLKQLLVHQWISQLQTRDQVWQRRLLKRSLDHLHDAESLRQRCSQLAYTLVGNSEAMTHLRAQVVRAAGSQLSVLIQGETGCGKDVVARGIHDMSDRASGPLVVVNCAAIPDTLLESELFGHTKGAFSGADQAKEGLLAQANGGTLFLDEIGDMPMALQSKLLRVLESRQFRPLGAREEQHSDFRLVAATHQPLQEGIEDGGFRRDLFYRLSQFPLRVLPLRERSEDLEALSRHFIRLYTEREGSGPLGISSHALSALADYHFPGNVRELRNIIELACLQTPAGDDIQPEVLRLDDLFADSPESTMAFVEAKTIPGVPPADDIRDLKAAAQAFEAAIIRERLRQYGGNRAQAAESLGLPKRTLAHKCLKYQVTDV
>NC_017067.1|WP_041655166.1|3750868_3751504_-|type-VI-secretion-system-associated-protein-TagO
MTLKDLHRLPLMVLLLVSTSSWADTRLAEARACTEQPNRLERLACFDEVFGTPLAQYEAGQHPALVNQSERWRRVFAQASGNDAGGVVYRDTGSAAGHLVTVTALGVKPPRPVLSLQCHNNITELAIMLPEPLDRERVDVTLGPHRAHWRVRDEGLVVSAGRGLPAIRTVLDVVNQPDVRLQAGVRELDGLLFDLNGFAEAIKPLRQTCGW
>NC_017067.1|WP_014422959.1|3749408_3750857_-|type-VI-secretion-system-protein-TssA
MQVIEQHPYVDQVLNAIPGDTGVGESLAEDSTLEFLEDEIMKVGSLAHNDIDWHKVESEALKLLADRSKDIKVLGFVMLSLQRGGDGERFALSLYLLHRVLDDWWENAWPYPGAKGQRARKMLFTQMLQRALKAVESLNFDASVGDGRQFCLDLVEKLDTQAKDRDLPDDALFDLKRAVEKLPKPDQATAPRTASESSPTNKQESTASSSPSSSASSNTTAASLGNLTLDPSNERATRQSLLKVAELLTSSEPDNALGYRMRRYAIWQSITSLPPTRDGKRTDLAAVSADRVAEYREALEKTPDLELWQRIEQSLSVSPFWLDGHWLSARAAMALGNTDCAEAIREALKAFVDRLPQLAELTFNDGTPFLSDDGADWLHTAPAAGKGTGAGANPWEQAFDGALELVRQNKLAPAMELLEQGLADAREPRERFYWRLATARLLKETGLKALAAEQIQDLKNQIQGRVLEDWEPALVKQLERLA
>NC_017067.1|WP_158011898.1|3745787_3749372_-|type-VI-secretion-system-membrane-subunit-TssM
MWRKALLIGRWLLPYIRSAAPVTLALGVIALLVATWWLGPRLEINGDYPLMAWQMRALVTLGVVLLVVMVWGTVLARRLGKVNKAKAEEQREQEDPILPMERRQQRLLDRQLQALKSNLPGRKGLYRLPWYLVMGLEDAGKTSLIQRAGQTYTLTNVTRNNRGDRNPFSFDWWIGDNGVLIDPDGELLSQNQGEGATGEIQSRLWNHFIAWLERSRPQRPLNGVILAVDLARLSAANEQQREAHAILLRTRLRELMEQLGSRLPVYVTFTKMDLMYGFAPFVRTLSKAEKDKALGFTFRLDGQQDQDQWLEQFAERYADMVDELTERLPDVLANTRDNEERAAAYSFTRQLAGLKPALEQFLTDLLSADAFSTPALVRGTYFTSVLQEGVPEDAFVSAAARNYQMSDPIQPAQRGGQSASLFTKGLFPEIIYPEAGLAGDNRRVVRQRHRRVAVAAVVALAAGAGMTAGWQHYFLQNAEAAAQVENRVKSYLNDWQPVGYEPDTTGRNLLQPLDELRDATLAFGDYRKEWPLVTDMGLYQGHKVGPEVDKAYLNMLAYQYLPALMFGVMEEMGQAPDNSTERLEHLRVLRMLYDASGRRTDIVSGYMREYWQARFPGQRDVQNRLYGHLQYAMAHTDLSDLAANGDPTATMALAPFRSSVEWAQHELGRISTSDRVYRELENEASRDFPTPLELARSSGPAFSTVFTRLDSYGEPLAEDVPSAEDPLSIPALLTREGLEKWFLRESGSVTELALIDAWVLGRRDDVDFSKADEAELLASLQTLYAEHYAEAWRTALSRLDIHRFEDLNHGVRILDSLTSGHQPLARLLAQVRENTRLIPVGEGEAEAARKLLEQSPHYRMLQDIERQFSDLNQLTRKQGEEQSGLEEVMLVVAELHEYMRNIQESPDTGKAALSAARARMGLQGADPIFTLQRMAGHQPEPLNRILNRLATESWRVVLDSAVAQLERDWYREVYQPFQQNLARHYPFTQGAGRDAALQDFERFFAPDGILETFYNDNLKLFLEDHPEHVGDARRASLVRRDVVAALDRARQIRQAFFTRSGTLDVEFALEPLNLSNNKRRSVVNIDGQLVEFSHGPSQSIPLVWPNTLRDTVESRVTLVPIQVNRSPRSISESGPWALFRLLGKADITGVSSNAVDVKFTVDDGEMRYRLHAASNTNPFTEQLLSGYRIPRSLY
>NC_017067.1|WP_041655667.1|3743560_3745684_-|type-VI-secretion-system-tip-protein-VgrG
MPQASGLQFTARVGEFPSDHFVVVGFALTERLSDLFHGRLQLASTDPDVAAADVLEQPVDLVVWQDGQPLRRFTGVVNEFMRGDTGHRRTRYEVVIQPPLWRLGLMHNSRIFQTQTTDAIVRTLLEERGIVDSIFDFKRPPEEREYCVQHRETDLQFLERLAAEEGWHYRYQHGSVDGEEQPALILADHHGDAPKLNPVTCNTKAGGSTKQACVFQFAYEERVKAASVAMKDYTFKNPAYALMHEQSAGGVNHREDYQHYDYPGRYKADASGQPFTQNKLDALRNDASMANGKSNRPDFTPGAKVELQDHDSQTLNREWLLTAITHTGKQPQALEEEGGSEPTSYHNTFSAIPADKTWRPLCNHKPVMDGPQMALVTGPEGEEIHCDQYGRVKVRFPWDRYSKNDEHSSAWLRVAQGWAGGQYGFMALPRIGHEVIVSFLDGDPDQPIITGRTYHATNTPPYALPEHKTRTTLKTKTHKGEGSNELRFEDEAGEEQVYVHAQKDLDLLTKNNRTEVIRNDSHLTVENNRFSHTKGNSHHTVDGEKREQTGKDHSFNVTGTLHLKAGTAWLSNSGTELHIKAGQKAVIEAGAEITLKAGGSFVKIDPSGVAMGGASIKMNAGGAAGKGSGQKVQVPEMPGLVTAAGGAVAPEALAEVSQRANAQPKAIVAHRLKQARMNRTAIVEQCQQKPDGTCPLGNCPCGKNQTA
>NC_017067.1|WP_041655666.1|3743002_3743545_-|DUF4123-domain-containing-protein
MVVFAQPSTDKVRFLVLEAQQKPSVVRSLYEQTDAPKWLYLFAETDWQQYLAESPVVLEAKQQSPEYQWALKGLKEGRLIGLILESSESLESVTSWLRARLTVRFDGERQGLLRLYDPEVWQRLSPGTQDQADVIERVIYWYGESGQERWQTTDRPSLFTMLPVPTLSETQWQALNTPEA
>NC_017067.1|WP_114435202.1|3738922_3742963_-|hypothetical-protein
MSENSAKQSTTGCSPTCEDESLIIEVIGKEHPDGHAFRIFDESNYEQQEWLEKQVEIEPLENSILHVWPWKGQPSRNVWIEIKSEDGPIRVPFLDDATSTEREVEHQRHVVLPVVPATLLSGIELHGQKPARQVLARAGFLYIFYKEKLWREIEIRIDEEGQTSYHDVALTKHRSRSGQLEPGYRKVTGSAMSEIWIPARINSDWLTLEMAFSESQWPGERVMHLERSATDRENRCVSIDMRFGSETKVSVENSNASSGNSVAFLAEYLSPQRSRVPALEWQFDRPDDYLLDLEGTYPDRAMQKAKSIHQRQESPDPEDPIAEDERPEMTALSNCLHRSLHQAEEALIQQCRPEDPEPFTWPGSGTAETDATINAKKRGIGVILLDDPIYQLRYNQRRRQVAAWYLNAAVRRAKARPYFDSALLVHSVIEPEHIASEPNQLHKHMAEINNQGRAELERSLAVSERQMGRAYLEKVHSELLELLSNERTHHVLTDLFTHDSYDYAGAFNFVTSLVMNLVTEPAECDALDIDVEGAVDGEGKHWLQGLCEGRHSRVLYSLLFPRFSPEDQKKPYQPPAEPQVNHGNGQFRETELAAMSITDLPDIDELKTIDGLELAVEAAAGSYETLLTANMRLGSQVLMSVHGNMWAAIHHASQAIEARNAKLAAIKKQLAELRIEISNLENQRWNIERRINNLRGKEAELEAIRNKLIELDVRFKELSRQKQSIMKTAVAGRMKLYSVSLEQLRRSLPELLGKVELMRLSKARQKDYFIFEFSEAELKSGTGKRAVELFGDLIQAGEEPDVRASTSRRRSKAAGIASEVAEDVYVLAVPKTETVVMLIEDIRKAESDFRQAVRALAELDELVGPSPGTPAAAMAAAAQRIEAAKAEVARAERELKAFEQEIDSRRSRVAKKEQYIRDLEAANDAANKIDQAEINSNRSSRLYRVLNKPAFPVFVGLIEVFNSASVWSASAHDGRVKGQLRADFRKFSAGFDLFVAGTAISERWVLGPSKILALELPEDIGRVFVKSLGAPLTVRSGLGAAAGFFMALDAGWDAYYEYRMGNHKAAFGYGLLAGSGIAFGFASVVGKSGLLLVLGPKGWLAVGVILAVAGLATVFAFSDEPLDIWMRHGPFGPLAEKPFLKKPDEAYYRLISQLMGVTVRLEYNPLRRMARDGVLEGYSDDQIAALSMAGERLVIESAIPELFSSGGGVTVLPKLQLNEMIAVAKGRSGHVQNNRIEGADVEPYVLMTEESGTGLHIYLNAPESARRRLDTAVWQSEAWETRTYRWKAKVQIQARQSLESMLMVFPAPPPQDPLVFSKSDERHTQPDFSSEDQPFWYSQRVQENAD
>NC_017067.1|WP_014422954.1|3737877_3738933_-|hypothetical-protein
MLIDVSPHGSSSDYYGSHSYRSDSIPEQSNQTQELNRTGLDRSASLRLPWGNTREVMPPTFMSRNPPKKLRRLEKKEDLAEKYGLHVESNHECFRHAPLALQARLVSIISVTGALWAYIVSPFAFFMLVLITLFGERERNWLDYSLDQALPYLIFLGGGWILILMAKLALRLFPKWLLRNGRGPEWEFNRRTGMIKVWQYPKKLPFLPRKPPVVVEKPFYEFDAWCCARVDRFGSLFDLVLSHRYSKLDVTVGDLLGAHGSPTMCYAYWDFIQNYMDITRPLPELPMLEQYRHLDPTTAKHDQATGRPARYWRDMDDKTFKQKVDDMFTDVSIIDTTRRPDLMAEKLNYAS
>NC_017067.1|WP_014422953.1|3737290_3737740_-|DUF4124-domain-containing-protein
MTRKLLISLFLLSLGPFSHAAVYQWTDANGQTHFGDRPPAKASSKEVRVNAAPAQADATARDRQQKMTEFLDQQQKEREERQAKEAKARQQAEKQEELCRNLQARLKHLESVSTFYDINEKGEREYVSEEENQQIRDRFRAKVKETCGE
>NC_017067.1|WP_014422952.1|3736169_3737264_+|rhomboid-family-intramembrane-serine-protease
MPRNRYRQCPACNTASLDSSSHPSIFDCRLCHGLWFEDGALNQAIAEHHDGVDQYDHEQHLGPALRTSDRLCRRCRVPMTHYQLLAHYTTEIDCCPGCDGVWLDKHEVDQVMQSPQLKQALKDLNQKVSWKSWLFQFLTAMPVEYNVKPHRTPWVTRTLVFLCALVFGVGALSAEANEWIFVNLGLNSDTQSPSHFVLQLLSYQFVHGGLMHLVGNMYFLWIIGDNLEDALGHGAFLALYLFAGIMAALVELLLFDASQGPLLLVGASGSIAALFGLYLMWFRHASLTFMIIVYQKKLAPHWYFLIWSLINLFGMFTAQGGVAWAAHLGGFGLGLLLGYLLRDYVLRKNPLIAMLNQPEAAINR
>NC_017067.1|WP_041655168.1|3753405_3756048_-|type-VI-secretion-system-ATPase-TssH
MIRVELPALIGRLNDISRQALEASAALCISRQGAEITPAHLLFKLLETPFSDVRQILEHTGINHQQLQPVVGDSLNGEPQTAEPYPSFSPLLVELMQDAWLLASTELGHTELRSGAVFLALLMNADRYLMPRVAQALVDINREQLRKQFDRVTEGSVERPQLTESGGARPAVESDMDPLKRYATDFTKLAREDKLDPVVCRDAEIDQMIDILCRRRKNNPIVVGDAGVGKSAVVEGLALRIVNGDVPDRLKNVELWTLDMGALQAGASVKGEFEKRLKGVIEAVKGSATPIILFIDEAHTLIGAGNSEGGSDAANLLKPALARGELRTIAATTWREYKKYFEKDPALSRRFQPVALDEPTPGEAVHILRGLRTVYEKAHQVLIADSALKAAAEMSARYLAGRQLPDKAIDVLDTACARVSLNLSTPPRRLSHVRSELHQLAMEQELLSREHTLGQNVDAEREQALEQKIADLTAESGALEQSWNDQRELVARLVEIREQLLVGDVERETADDVAVELAESDHEERPDLKSEAAAIEQELAELQADEPLVHARVDARQVAEVIADWTGIPVNRMTTDELEKITHLPAYLQAHIKGQDTAIDCLHQHLLTARADLRRPGRPMGAFLLVGPSGVGKTETVVQLAELLYGGRQFLTTINMSEYQEKHTVSRLIGSPPGYVGFGEGGILTEAIRQKPYSVVLLDEVEKAHPEVLNLFYQAFDKGELADGEGRLIDCKNVVFFLTSNLGFQTIVNHAEEPEKIEEALYPELANFFKPALLARMEVVPYLPLGEDTLNRIVEDKLQRLADQIQARYHTEVELEDGLVEAIRSRATRSENGARMLESIIEGELLPPVSLALLEKLAAREPVTKVKLGVEENRFTGTVA
>NC_017067.1|WP_014422963.1|3756058_3756880_-|DotU-family-type-IV/VI-secretion-system-protein
MADAPVMDRPDNTRDSGDRAFSDLLFADSGAGQSPVESDDSSFQLRGLEDNRLIDAATPLLGLVIRVRRLADFREVETLYRQVVDEVAAVDRELVEQGYERPTVVAYRYVLCAFIDEAVLGTDWGAHSVWSQHSLLSRFHNETWGGEKVFAILARMEKEPTRYRDMLEFIYLCLCLGFEGRYKVMENGRDEYEQVVRGLYDQLRELRGDRDSRPLADATENLMPARNRLRSGLPLWGIGGLFVAAMAGIYSLYNMALNERIRDVLSVLEQLPK
>NC_017067.1|WP_014422964.1|3756883_3758218_-|type-VI-secretion-system-baseplate-subunit-TssK
MAVTNRVVWSDGLFIKPQHFQQQQRYLEHQINERALAVSDYLFGFSDLELNAEYLSFGRVGLVRASGLFPDGTRFNLPQDDVMPEPLEITDASVANQVVYLALPLGSDSLAEVEWPEAPVAGRFQAQPVEVRDLHSIDGDAHTIDVGRVAPRLMLEREDRSAYAALAIGRILEKRPDGSLVMDPNFLPTMLSVRSAPRLQRFVGEMAGLMQERARNIAERVGAPGQGGVADVSDFMLLQMLNRAHPRFMHLARLRQLHPERLYEALLELCGELVTFTDESRLPREFTPYDHDLPEGCFSPLMQILRQALSTVLEPRALSIALQQRQYGLTVAPVQDGQLMNDAEFILAVKADMPLDDLRKQFVQQCKVASVEKIRDLISLQLPGIPLSALPVAPRQLPYHAGFVYFRLDDQSQAWQMLDNASGFAFHVAGSFPGLEMQFWAIRS
>NC_017067.1|WP_011787131.1|3758217_3758751_-|type-VI-secretion-system-lipoprotein-TssJ
MKYCKWSLLVVALILAGCSTPYNAVTKTAKVLWDPDIPVGYPEDLPSRVDLTMLAEPNVNPNESLAPTPIAFQVIELRDSSLLMAGDFDQLLNDLEDSLGQNYVDHSDYSLVPGQFKFVEPFEVSTDTRYIAVIAFYAYPNLSQWKKVVKVDPIGGRYHLLVNLREREVQLRRSDES
>NC_017067.1|WP_014422965.1|3758747_3760058_-|type-VI-secretion-system-associated-FHA-domain-protein-TagH
MAQQAAELTLVITNPTEIGGGASIEHSFGTRGGSIGTAASDSWQLSPHRTGAVAGHAEVRYLDGGFCLIDRSGRTYINSSSQPVGRGRRARLSHGDTVTIGRYQIRAELSGVPAAVGETDHDAREDHGLVDAPENGLRHAANEQNRPEGREPLEGLQPAAGDPVSCDPLAPWQQKPTRPDEEAPELLASDQAWFARSAEVSDEYRENRDVAMGLPVTPQREHKERQGMSETTRNMREVSRQHISGAPLLRGLDADIDFADSDEMRLFLEEAGQTLKATVEGLLALHQGEDSRHQALRTRLQPIEDNPLRLANDYSDTIQTLFAAQRSPVHLSAPAAVRESLESLNHHQQATREAIREALEAILHAFSPEALLRRFHGYRRGLQDNEDEGRWAWDMYQHYYRELKSSRQQGFERLFQEVFDQAYDQHLRQLQREKLL
>NC_017067.1|WP_014422966.1|3760075_3761092_-|type-VI-secretion-system-baseplate-subunit-TssG
MDVTARSAAADVAGLEPVLGNARRYSFFQLVDLIHRHHGDDLERGGHDEPRQERIRFSASAGLGFPGSDVVSALSPEHEHAPYQMEVSFLGLHGSQSPLPGYYLEDLAWEAGQNLGVRRHFLDFFNHRLVTLFHRAWRKYRYYIRFQPGASDGFSELVFALTGLGDSRLREATPVNWSKMLAYAGLMAGRSRSPEVVSGIIGHCFDLDDVSIEQWVLRKVDIARDQQTALGRANATLGEDTLVGSRIRDRSGKFILRLRNLTRQRFADFLPNGRDHQRLVKLVEFATREQLAYDLELQMRPKDIRPMQLGEDVRLGWNSFVTPDRARERPAVRIQIRR
>NC_017067.1|WP_014422967.1|3761055_3762828_-|type-VI-secretion-system-baseplate-subunit-TssF
MKLNRFYRDELSFLRLQGREFAEAHPQLTRFLSEQSTDPDVERLLEGFAFLTGKLREKVEDEFPELTHSLLNMLWPNYLRPVPSCTIMRFDPQLHAISERQVVDRHTEIKSRPLGDASRQTQCRFRTCRAVDIFPISVAEANAEHSREVSSVTVDLALHTDQPLNGIGLENLRFYLGGDNHTAETLYLWLNHYLSRMELVVGDRVFSLPSSLLQPVGFAADEAILPYPKNAYAGYRIIQEYLSFPEAFRFVDITGLKSRLPAVQADEISLRFHFSRILPPDTRVTRDSMQLYCTPAVNLFSHEGEPVDLNGRQTEYRISPSSRCPEHYEVFSIEQVEGWLEGRSGRGEPRIYTAFESFQHEVERDRGRTALYYRVRTRESVRGDGFDHYISFVRGDETECLNRQEAVSLTLTCTNRQLPQQLAVGEVCMATESTPAFAAFSNITRPTATLRPTLDGSLLWTLISNLSLNYLSMLDVDALRTVLRVYDFRALVDRQAERVSQKRLAGITGITTKPVDRMIRGLPVRGIRSELKLDQHGFASEGDLYLFGTVLSQFFALYASINAFHQLEVVNTDNQERYTWTLQQGQQPLM
>NC_017067.1|WP_014422969.1|3763126_3763564_-|type-VI-secretion-system-baseplate-subunit-TssE
MFGGTGTDGVRNTGSLFERLEQAAAPAGQSMGEFTHVVESIKRHLVRLLNAHPGNSSSAPDLGLLDFNDATLGTHDLSIQIRGAIRQCIEKFEPRVKRVDVVAMPPGPDPLQLKFQVTVYLNVAGSDDRTTIDLVLDDKRYCRVV
>NC_017067.1|WP_011787136.1|3763567_3765049_-|type-VI-secretion-system-contractile-sheath-large-subunit
MSDTAVQQSAASESVAEGSLLDQVMANSRMAPADEGYDVARKGVATFIANLLKSDEKGQPVNKALVDQMVVELDRKISAQMDEILHAPKLQELESSWRGLKLMVDRTDFRENIKVDILHATKTELLEDFEFAPDVTQTGFYKHIYAAEYGQFGGEPVGAIVGNYAFSPSTPDMKLLQYVSSVGAMSHAPFLSSVAPSFFGVDSYQELPAIKELSAVFEGPKYAKWRSLRESEDARYLGLTAPRFLLRVPYDPTENPVRSFNYKEDVSGDHEHYLWGNTSYLLATRLTESFAKYRWCPNIIGPQSGGAVEDLPVHTFESFGQLEAKIPTEVLITDRREYELAEEGFIALTMRKGSDNAAFFSANSVQKPKQFPNTKEGKEAETNYKLGTQLPYMMIVNRLAHYIKVLQREQIGSWKERQDLERELNTWIRQYVADQENPPADVRSRRPLRAAKVEVSDVEGDPGWYQVSLAVRPHFKYMGANFELSLVGRLDKD
>NC_017067.1|WP_011787137.1|3765110_3765608_-|type-VI-secretion-system-contractile-sheath-small-subunit
MSAKDGSVAPKERINIKYVPATGDQQAETELPLKMFVVGDFKGHAEETPIEDRKAISVDKNNFRSVMKEAGLTLSTSVSNKLEDGADDLPVNLEFQGLEDFSPDSIARQVPELKKLIELREALVALKGPLGNVPSFRSKLQELLDNDDAREKLLAELELATDGGE

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

540625 : 550174

Vibrio_phage(33.33%)

tRNA,integrase

attL 539854:539867|attR 544476:544489

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
539854:539867	attL	NA	NA	NA	NA
WP_014420439.1\|540625_541921_+	hypothetical protein	A0A0N9H972	Vibrio_phage	3.8e-34	35.1
WP_014420441.1\|542048_543314_+	hypothetical protein	Q56VN8	Pseudomonas_phage	1.2e-56	33.2
WP_014420442.1\|543310_544285_+\|integrase	tyrosine-type recombinase/integrase	A0A218M4I3	Erwinia_phage	3.6e-85	49.2
WP_158011864.1\|544298_544592_+	hypothetical protein	NA	NA	NA	NA
544476:544489	attR	NA	NA	NA	NA
WP_041654532.1\|544788_546645_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	4.0e-37	33.2
WP_014420445.1\|546763_548515_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	1.7e-74	38.2
WP_007153483.1\|548669_548885_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_041654533.1\|549118_550174_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	5.0e-109	58.4

DBSCAN-SWA_2

3703700 : 3762828

Tupanvirus(14.29%)

protease,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014422931.1\|3703700_3705152_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_011787086.1\|3705377_3705818_+	OmpA family protein	NA	NA	NA	NA
WP_014422932.1\|3705875_3706277_-	MAPEG family protein	NA	NA	NA	NA
WP_011787088.1\|3706278_3706521_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_011787089.1\|3706592_3707312_-	1-acylglycerol-3-phosphate O-acyltransferase	NA	NA	NA	NA
WP_011787090.1\|3707361_3707949_-	class GN sortase	NA	NA	NA	NA
WP_014422934.1\|3707945_3710084_-	VWA domain-containing protein	A0A2K9L1L0	Tupanvirus	2.0e-16	20.6
WP_014422935.1\|3710273_3710975_+	proteobacterial dedicated sortase system response regulator	NA	NA	NA	NA
WP_014422936.1\|3710978_3713015_+	proteobacterial dedicated sortase system histidine kinase	NA	NA	NA	NA
WP_014422937.1\|3713011_3714319_+	DUF3422 domain-containing protein	NA	NA	NA	NA
WP_014422938.1\|3714323_3715103_-	ATP-binding protein	NA	NA	NA	NA
WP_041655664.1\|3715353_3718161_+	transporter substrate-binding domain-containing protein	A0A127AWB9	Bacillus_phage	2.1e-13	34.5
WP_041655161.1\|3718177_3719149_+	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	1.1e-75	52.4
WP_011787098.1\|3719221_3719800_-	porin family protein	NA	NA	NA	NA
WP_014422941.1\|3719920_3720217_-	hypothetical protein	NA	NA	NA	NA
WP_041655162.1\|3720213_3721128_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_011787101.1\|3721335_3721935_+\|protease	ATP-dependent zinc protease	NA	NA	NA	NA
WP_014422943.1\|3721936_3722824_-	DNA ligase	F2Y1N0	Organic_Lake_phycodnavirus	4.9e-25	34.0
WP_014422944.1\|3722875_3723313_-	YtoQ family protein	NA	NA	NA	NA
WP_014422945.1\|3723401_3724721_-	glycerophosphoryl diester phosphodiesterase	NA	NA	NA	NA
WP_014422946.1\|3724922_3726332_+	hypothetical protein	A0A2H5BGM4	Vibrio_virus	1.2e-33	41.8
WP_014422947.1\|3726391_3731641_-	DNA repair ATPase	NA	NA	NA	NA
WP_014422948.1\|3731730_3733734_-	hypothetical protein	NA	NA	NA	NA
WP_014422949.1\|3733777_3734404_-	hypothetical protein	NA	NA	NA	NA
WP_011787109.1\|3734609_3735014_+	YjfI family protein	NA	NA	NA	NA
WP_014422950.1\|3735028_3735727_+	PspA/IM30 family protein	NA	NA	NA	NA
WP_014422951.1\|3735793_3736126_+	hypothetical protein	NA	NA	NA	NA
WP_014422952.1\|3736169_3737264_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_014422953.1\|3737290_3737740_-	DUF4124 domain-containing protein	NA	NA	NA	NA
WP_014422954.1\|3737877_3738933_-	hypothetical protein	NA	NA	NA	NA
WP_114435202.1\|3738922_3742963_-	hypothetical protein	NA	NA	NA	NA
WP_041655666.1\|3743002_3743545_-	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_041655667.1\|3743560_3745684_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	2.0e-32	25.6
WP_158011898.1\|3745787_3749372_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_014422959.1\|3749408_3750857_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_041655166.1\|3750868_3751504_-	type VI secretion system-associated protein TagO	NA	NA	NA	NA
WP_014422961.1\|3751500_3753066_-	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_041655168.1\|3753405_3756048_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	3.5e-95	33.7
WP_014422963.1\|3756058_3756880_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_014422964.1\|3756883_3758218_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_011787131.1\|3758217_3758751_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_014422965.1\|3758747_3760058_-	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_014422966.1\|3760075_3761092_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_014422967.1\|3761055_3762828_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA

DBSCAN-SWA_3

3895098 : 3924317

Catovirus(20.0%)

integrase,holin,transposase

attL 3910627:3910641|attR 3929397:3929411

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041655235.1\|3895098_3896316_-\|holin	choline transporter	NA	NA	NA	NA
WP_011787242.1\|3896526_3898212_-\|holin	choline dehydrogenase	A0A1V0S9J5	Catovirus	1.6e-61	30.7
WP_041655238.1\|3898239_3899709_-	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_023008748.1\|3899771_3900365_-	transcriptional regulator BetI	NA	NA	NA	NA
WP_041655249.1\|3900561_3901371_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_041655677.1\|3901524_3904128_+	EAL domain-containing protein	NA	NA	NA	NA
WP_041655251.1\|3904124_3905540_-	cytochrome P450	NA	NA	NA	NA
WP_023007704.1\|3905575_3905896_-	2Fe-2S iron-sulfur cluster binding domain-containing protein	NA	NA	NA	NA
WP_014423085.1\|3906067_3907096_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_014423086.1\|3907526_3907934_-	GFA family protein	NA	NA	NA	NA
WP_041655255.1\|3908093_3909311_+	diguanylate cyclase	G3MA91	Bacillus_virus	7.7e-21	31.8
WP_014423088.1\|3909339_3910209_-	LysR family transcriptional regulator	A0A2H4J8I9	uncultured_Caudovirales_phage	1.5e-05	34.6
WP_014423089.1\|3910303_3910804_+	lactoylglutathione lyase family protein	NA	NA	NA	NA
3910627:3910641	attL	NA	NA	NA	NA
WP_014423091.1\|3911419_3911752_-	hypothetical protein	NA	NA	NA	NA
WP_041655261.1\|3911847_3912258_-	VOC family protein	NA	NA	NA	NA
WP_041655682.1\|3912402_3913302_-	SMEK domain-containing protein	NA	NA	NA	NA
WP_014423095.1\|3913746_3914286_-	YcxB family protein	NA	NA	NA	NA
WP_014423096.1\|3914403_3915429_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_158011903.1\|3915769_3916054_-	hypothetical protein	NA	NA	NA	NA
WP_081496580.1\|3916150_3917269_-	SEC-C domain-containing protein	NA	NA	NA	NA
WP_014423099.1\|3917352_3918066_-	FRG domain-containing protein	A0A1S6KZX9	Salmonella_phage	4.9e-07	25.2
WP_041655267.1\|3918884_3919928_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_050999057.1\|3920390_3920819_-	HAD family hydrolase	NA	NA	NA	NA
WP_041655270.1\|3920952_3921582_-	LysE family transporter	NA	NA	NA	NA
WP_014423105.1\|3921673_3922009_-	DUF2314 domain-containing protein	NA	NA	NA	NA
WP_041655279.1\|3922341_3923466_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_041655282.1\|3923465_3924317_-\|integrase	site-specific integrase	A0A1L4BKH1	Thermus_phage	1.1e-13	30.8
3929397:3929411	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage