CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NC_018660	Escherichia coli O104:H4 str. 2011C-3493 plasmid pG-EA11, complete sequence	0 crisprs	NA	0	0
NC_018666	Escherichia coli O104:H4 str. 2011C-3493 plasmid pAA-EA11, complete sequence	0 crisprs	RT	0	1
NC_018658	Escherichia coli O104:H4 str. 2011C-3493, complete sequence	8 crisprs	csa3,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,c2c9_V-U4,DinG,PrimPol,RT	15	14
NC_018659	Escherichia coli O104:H4 str. 2011C-3493 plasmid pESBL-EA11, complete sequence	0 crisprs	NA	0	1

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

38617 : 45571

Stx2-converting_phage(57.14%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000019440.1\|38617_39598_+\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	6.8e-185	99.1
WP_001339397.1\|40325_41003_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_000624622.1\|41002_41350_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_000381397.1\|41369_42941_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	2.2e-169	58.5
WP_000624689.1\|43253_43550_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	3.4e-31	64.4
WP_001387845.1\|43546_43981_-	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	3.4e-19	60.3
WP_000139330.1\|44209_44770_-	fertility inhibition protein FinO	NA	NA	NA	NA
WP_000205736.1\|44824_45571_-	conjugal transfer pilus acetylase TraX	A0A077JBM8	Xanthomonas_phage	3.2e-09	30.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_018658

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CRISPR-Cas detection and classification

Crispr_ID: NC_018658_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018658_1

677951-678202

Orphan

Consensus_repeat	Method
TTTTGGAGGAGCAGAAAGATGAATGACTGTCCACGACGCTATACCCAAAAGAAA	PILER-CR

2 spacers

The CRISPR arrays of NC_018658_1

>merge|NC_018658|1|677951-678202|PILER-CR
AGATGAATGACTGTCCACGACAGAACCCGGCTTATCGGTCAGTTTCACCTGATTTACGTAAAAACCCGCTTCGGCGGGTTTTTGCTTTTGGAGGAGCGGAAAGATGAATGACTGTCCACGACGCTATACCCAAAAGAAAGCGGCTTATCGGTCAGTTTCACCTGGTTTACGTAAAAAACCGCTTCGGCGGGTTTTTGCTTTTGGAGGGGCAGAAAGATGAATGACTGTCCACGACGCTATACCCAAAAGAAA

>NC_018658|1|1|677951-678202|PILER-CR
AGATGAATGACTGTCCACGACAGAACCCGGCTTATCGGTCAGTTTCACCTGATT	TACGTAAAAACCCGCTTCGGCGGGTTTTTGCTTTTGGAGGAGCGGAAAGATGAATGACTGTCCA
CGACGCTATACCCAAAAGAAAGCGGCTTATCGGTCAGTTTCACCTGGTTTACGT	AAAAAACCGCTTCGGCGGGTTTTTGCTTTTGGAGGGGCAGAAAGATGAATGACTGTCCA
CGACGCTATACCCAAAAGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_018658.1\|WP_000399648.1\|678461_679442_-\|IS110-like-element-IS621-family-transposase	unknown	unknown	gnl\|CDD\|376773
NC_018658.1\|WP_000107720.1\|684364_685696_+\|threonine/serine-transporter-TdcC	unknown	unknown	gnl\|CDD\|184191
NC_018658.1\|WP_000599636.1\|673308_674643_+\|galactarate/glucarate/glycerate-transporter-GarP	unknown	unknown	gnl\|CDD\|273326
NC_018658.1\|WP_000548347.1\|683353_684343_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	unknown	unknown	gnl\|CDD\|236317
NC_018658.1\|WP_000861734.1\|686963_689258_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	unknown	unknown	gnl\|CDD\|153087
NC_018658.1\|WP_001299416.1\|676445_677591_+\|glycerate-2-kinase	unknown	unknown	gnl\|CDD\|182392
NC_018658.1\|WP_000145820.1\|681783_682128_-\|DNA-binding-transcriptional-activator-TdcR	unknown	unknown	gnl\|CDD\|236909
NC_018658.1\|WP_001058227.1\|674658_675429_+\|2-dehydro-3-deoxyglucarate-aldolase	unknown	unknown	gnl\|CDD\|182547
NC_018658.1\|WP_000681935.1\|668022_669303_-\|tagatose-bisphosphate-aldolase-subunit-KbaZ	unknown	unknown	gnl\|CDD\|185355
NC_018658.1\|WP_000347267.1\|670415_670880_-\|type-II-toxin-antitoxin-system-ribonuclease-toxin-YhaV	unknown	unknown	gnl\|CDD\|371659
NC_018658.1\|WP_000072187.1\|669551_670361_+\|aga-operon-transcriptional-regulator-AgaR	unknown	unknown	gnl\|CDD\|182086
NC_018658.1\|WP_001295547.1\|667526_668000_-\|PTS-N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|183129
NC_018658.1\|WP_001303675.1\|675458_676349_+\|2-hydroxy-3-oxopropionate-reductase	unknown	unknown	gnl\|CDD\|183197
NC_018658.1\|WP_000484578.1\|679779_680967_-\|YhaC-family-protein	unknown	unknown	gnl\|CDD\|182043
NC_018658.1\|WP_001307405.1\|670879_671215_-\|type-II-toxin-antitoxin-system-antitoxin-PrlF	unknown	unknown	gnl\|CDD\|236638
NC_018658.1\|WP_001273741.1\|671363_672935_-\|galactarate-dehydratase	unknown	unknown	gnl\|CDD\|274491
NC_018658.1\|WP_000104211.1\|682316_683255_+\|transcriptional-regulator-TdcA	unknown	unknown	gnl\|CDD\|182391
NC_018658.1\|WP_000675746.1\|680988_681528_-\|hypothetical-protein	unknown	unknown	unknown
NC_018658.1\|WP_001352528.1\|685721_686930_+\|propionate-kinase	unknown	unknown	gnl\|CDD\|183484
NC_018658.1\|WP_000719990.1\|689271_689661_+\|enamine/imine-deaminase	unknown	unknown	gnl\|CDD\|105214

Protein	Function_ID	Function_description	E-value
NC_018658.1\|WP_000399648.1\|678461_679442_-\|IS110-like-element-IS621-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	1.78707e-27
NC_018658.1\|WP_000107720.1\|684364_685696_+\|threonine/serine-transporter-TdcC	gnl\|CDD\|184191	PRK13629, PRK13629, threonine/serine transporter TdcC; Provisional.	0
NC_018658.1\|WP_000599636.1\|673308_674643_+\|galactarate/glucarate/glycerate-transporter-GarP	gnl\|CDD\|273326	TIGR00893, Probable_glucarate_transporter, D-galactonate transporter. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	7.8374e-134
NC_018658.1\|WP_000548347.1\|683353_684343_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	gnl\|CDD\|236317	PRK08638, PRK08638, bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB.	0
NC_018658.1\|WP_000861734.1\|686963_689258_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	gnl\|CDD\|153087	cd01678, PFL1, Pyruvate formate lyase 1. Pyruvate formate lyase catalyzes a key step in anaerobic glycolysis, the conversion of pyruvate and CoenzymeA to formate and acetylCoA. The PFL mechanism involves an unusual radical cleavage of pyruvate in which two cysteines and one glycine form radicals that are required for catalysis. PFL has a ten-stranded alpha/beta barrel domain that is structurally similar to those of all three ribonucleotide reductase (RNR) classes as well as benzylsuccinate synthase and B12-independent glycerol dehydratase.	0
NC_018658.1\|WP_001299416.1\|676445_677591_+\|glycerate-2-kinase	gnl\|CDD\|182392	PRK10342, PRK10342, glycerate kinase I; Provisional.	0
NC_018658.1\|WP_000145820.1\|681783_682128_-\|DNA-binding-transcriptional-activator-TdcR	gnl\|CDD\|236909	PRK11424, PRK11424, DNA-binding transcriptional activator TdcR; Provisional.	3.36123e-66
NC_018658.1\|WP_001058227.1\|674658_675429_+\|2-dehydro-3-deoxyglucarate-aldolase	gnl\|CDD\|182547	PRK10558, PRK10558, alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional.	0
NC_018658.1\|WP_000681935.1\|668022_669303_-\|tagatose-bisphosphate-aldolase-subunit-KbaZ	gnl\|CDD\|185355	PRK15458, PRK15458, tagatose 6-phosphate aldolase subunit KbaZ; Provisional.	0
NC_018658.1\|WP_000347267.1\|670415_670880_-\|type-II-toxin-antitoxin-system-ribonuclease-toxin-YhaV	gnl\|CDD\|371659	pfam11663, Toxin_YhaV, Toxin with endonuclease activity, of toxin-antitoxin system. YhaV causes reversible bacteriostasis and is part of a toxin-antitoxin system in Escherichia coli along with PrlF. The toxicity of YhaV is counteracted by PrlF by the formation of a tight complex which binds to the promoter of the prlF-yhaV operon. In vitro, YhaV also has endonuclease activity.	3.36297e-73
NC_018658.1\|WP_000072187.1\|669551_670361_+\|aga-operon-transcriptional-regulator-AgaR	gnl\|CDD\|182086	PRK09802, PRK09802, DeoR family transcriptional regulator.	0
NC_018658.1\|WP_001295547.1\|667526_668000_-\|PTS-N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|183129	PRK11425, PRK11425, PTS N-acetylgalactosamine transporter subunit IIB.	2.31755e-109
NC_018658.1\|WP_001303675.1\|675458_676349_+\|2-hydroxy-3-oxopropionate-reductase	gnl\|CDD\|183197	PRK11559, garR, tartronate semialdehyde reductase; Provisional.	0
NC_018658.1\|WP_000484578.1\|679779_680967_-\|YhaC-family-protein	gnl\|CDD\|182043	PRK09716, PRK09716, YhaC family protein.	0
NC_018658.1\|WP_001307405.1\|670879_671215_-\|type-II-toxin-antitoxin-system-antitoxin-PrlF	gnl\|CDD\|236638	PRK09974, PRK09974, type II toxin-antitoxin system PrlF family antitoxin.	5.08893e-52
NC_018658.1\|WP_001273741.1\|671363_672935_-\|galactarate-dehydratase	gnl\|CDD\|274491	TIGR03248, galactar-dH20, galactarate dehydratase. Galactarate dehydratase converts D-galactarate to 5-dehydro-4-deoxyglucarate which is subsequently acted on by GarL, tartronate semialdehyde reductase and glycerate kinase (GenProp0714).	0
NC_018658.1\|WP_000104211.1\|682316_683255_+\|transcriptional-regulator-TdcA	gnl\|CDD\|182391	PRK10341, PRK10341, transcriptional regulator TdcA.	0
NC_018658.1\|WP_001352528.1\|685721_686930_+\|propionate-kinase	gnl\|CDD\|183484	PRK12379, PRK12379, propionate kinase.	0
NC_018658.1\|WP_000719990.1\|689271_689661_+\|enamine/imine-deaminase	gnl\|CDD\|105214	PRK11401, PRK11401, enamine/imine deaminase.	2.43767e-83

>NC_018658.1|WP_001299416.1|676445_677591_+|glycerate-2-kinase
MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSIPVADGGEGTVEAMIAATQGSERHAWVTGPLGEKVNASWGISGDGKTAFIEMAAASGLELVPAEKRDPLVTTSRGTGELILQALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGNEIGFGGGSLNTLNDIDISGLDPRLKDCVIRVACDVTNPLVGDNGASRIFGPQKGASEAMIVELDNNLSHYADVIKKALHVDVKDVPGAGAAGGMGAALMAFLGAELKSGIEIVTTALNLEEHIHDCTLVITGEGRIDSQSIHGKVPIGVANVAKKYHKPVIGIAGSLTDDVGVVHQHGIDAVFSVLTSIGTLDEAFRGAYDNICRASRNIAATLAIGMRNAG
>NC_018658.1|WP_001303675.1|675458_676349_+|2-hydroxy-3-oxopropionate-reductase
MTMKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDVIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLGTADHSALACYYEKLAKVEVTR
>NC_018658.1|WP_001058227.1|674658_675429_+|2-dehydro-3-deoxyglucarate-aldolase
MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVETKEEAEQAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK
>NC_018658.1|WP_000599636.1|673308_674643_+|galactarate/glucarate/glycerate-transporter-GarP
MILDTVDEKKKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVFTVMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLHYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGFAGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLLASTIILCNYTNNTTLVVMLMALAFFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALVFVGCSALMAMVCYLFVVGDIKRMELQK
>NC_018658.1|WP_001273741.1|671363_672935_-|galactarate-dehydratase
MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPAPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLVGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQVAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT
>NC_018658.1|WP_001307405.1|670879_671215_-|type-II-toxin-antitoxin-system-antitoxin-PrlF
MPANARSHAVLTTESKVTIRGQTTIPAPVREALKLKPGQDSIHYEILPGGQVFMCRLGDEQEDHTMNAFLRFLDADIQNNPQKTRPFNIQQGKKLVAGMDVNIDDEIGDDE
>NC_018658.1|WP_000347267.1|670415_670880_-|type-II-toxin-antitoxin-system-ribonuclease-toxin-YhaV
MDFPQRVNGWALYAHPCFQETYDALVAEVETLKGKDPENYQRKAATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKNKDWSRVKFGAGRYRLFFRYSEKEKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWESLTQETEENH
>NC_018658.1|WP_000072187.1|669551_670361_+|aga-operon-transcriptional-regulator-AgaR
MSNTDASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALICDSTTPSVEPSVEDKSALNTAMKRSVAKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLRRQSQSFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPADSLEGLRKAGVEVILVGE
>NC_018658.1|WP_000681935.1|668022_669303_-|tagatose-bisphosphate-aldolase-subunit-KbaZ
MKHLTEMVRQHKAGKTNGIYAVCSAHPLVLEAAIRYASANQTPLLIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCREHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWPRIIALVVQPGVEFDHTNVIDYQPAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVQEDVMLDRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGELQPTPRELIINHIQDILAQYHTACEGQ
>NC_018658.1|WP_001295547.1|667526_668000_-|PTS-N-acetylgalactosamine-transporter-subunit-IIB
MPNIVLSRIDERLIHGQVGVQWVGFAGANLVLVANDEVAEDPVQQNLMEMVLAEGIAVRFWTLQKVIDNIHRAADRQKILLVCKTPADFLTLVKGGVPVNRINVGNMHYANGKQQIAKTVSVDAGDIAAFNDLKAAGVECFVQGVPTEPAVDLFKLL
>NC_018658.1|WP_000399648.1|678461_679442_-|IS110-like-element-IS621-family-transposase
MEHELHYIGIDTAKEKLDVDVLRPDGRHRTKKFANTTKGHDELVSWLKGHKIDHAHICIEATGTYMEPVAECLYDAGYIVSVINPALGKAFAQSEGLRNKTDTVDARMLAEFCRQKRPAAWEAPHPLERALRALVVRHQALTDMHTQELNRTETAREVQRPSIDAHLLWLEAELKRLEKQIKDLTDDDPDMKHRRKLLESIPGIGEKTSAVLLAYIGLKDRFAHARQFAAFAGLTPRRYESGSSVRGASRMSKAGHVSLRRALYMPAMVATSKTEWGRAFRDRLAANGKKGKVILGAMMRKLAQVAYGVLKSGVPFDASRHNPVAA
>NC_018658.1|WP_000484578.1|679779_680967_-|YhaC-family-protein
MFPVSSIGNDISSDLVRRKMNDLPESPIVNNLEALAPGIEKLKQTSIQMVTLLNALQPGGKCIITGDFQKELAYLQNVILYNDSSLRMDFFGYNALIIQRSDNTCELTINEPLKNQEISTGNINVNFPLKDIYNEIRRLNVVFSCGTGGIVDLSSLDLRNIYLELYDFTDKHMANAILNPFKLDDTDFTNANMFQVNFVSSKQNTTISWDYLLKITPVLTSISDMYSEEKIKLVESCLNELGDITEEQLKIMRFAIIESIPRATLTDQLENELTKEIYKNSSKINNYLNRIKLPEMKGFSSEKIDYYIDIIIKDYESVKENAYLIDPKINYNTDLNIEDSSSEEFLSDNTLEKDENSPDNCFEVVKYNTYEAYNSENLYFTREEYTYDYDLLNAI
>NC_018658.1|WP_000675746.1|680988_681528_-|hypothetical-protein
MKGFPIAHIFHPSIPPMHAVVNNHNRNIDYWTVKRKFAEIVSTNDVNKIYSISNELRRVLSAITALNFYQGDVPSVMIRIQPENMSPFIIDISTGEHDDYIIQTLDVGTFAPFGEQCTCSAVNKKELECIKETISKYCAKFTRKEAILTPPAHFNKTSITSDCWQILFFSPDHFNNDFY
>NC_018658.1|WP_000145820.1|681783_682128_-|DNA-binding-transcriptional-activator-TdcR
MTGITIFYGDNIIRYVVNIKKGLRPYFKQLPDNYQAKFELNLMSKFSNFIINKPFSAINTAARHIFSRYLLENKHLFYQYFKISNTGIDHLEQLINVNFFSSDRTSFCECNRFP
>NC_018658.1|WP_000104211.1|682316_683255_+|transcriptional-regulator-TdcA
MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIINDIEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFGFPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKLQDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNGISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAVWSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG
>NC_018658.1|WP_000548347.1|683353_684343_+|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB
MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAASFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA
>NC_018658.1|WP_000107720.1|684364_685696_+|threonine/serine-transporter-TdcC
MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
>NC_018658.1|WP_001352528.1|685721_686930_+|propionate-kinase
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVVIDTEMNNRSNSFGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
>NC_018658.1|WP_000861734.1|686963_689258_+|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase
MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGDESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIVGLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPDMLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDLEATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNGGAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSGDPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYAAQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYAINGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDKYSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDGEYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNTPDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKEDPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGYAVRFNALTREQQQDVISRTFTQAL
>NC_018658.1|WP_000719990.1|689271_689661_+|enamine/imine-deaminase
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATYPTRSCVQVARLPKDVKLEIEAIAVRSA

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Crispr_ID: NC_018658_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018658_2

1161011-1161832

Orphan

I-E

Consensus_repeat	Method
GAGTTCCCCGCGCCAGCGGGGATAAACC	PILER-CR
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

13 spacers

The CRISPR arrays of NC_018658_2

>merge|NC_018658|2|1161011-1161832|PILER-CR,CRISPRCasFinder,CRT
GAGTTCCCCGCGCCAGCGGGGATAAACCAGGAACTGGCGCTGCTGGAGCAAAACCCGGTATGAGTTCCCCGCGCCAGCGGGGATAAACCGAAAAGGGCCGCATTGACGGCCCTGTGTTATCGGAGTTCCCCGCGCCAGCGGGGATAAACCGTTAGCTGTTAGCCAAACATGTCGACCTGTTTGGAGTTCCCCGCGCCAGCGGGGATAAACCGGGGTGGCGGTGGTGCTGTAATTCACACCGGTAGAGTTCCCCGCGCCAGCGGGGATAAACCGTATTCCCCCAGTCACCCCCGCCACCAAAATCAGAGTTCCCCGCGCCAGCGGGGATAAACCGATTTTTCAGACTCATCAAAATAATCCTTTAATGAGTTCCCCGCGCCAGCGGGGATAAACCGCATTGCCTTTGCAGCGTCTTTCCGATCATTCAGAGTTCCCCGCGCCAGCGGGGATAAACCGAACGTGAGATACGCCTCCCAGCGGCGCTCGGTGAGTTCCCCGCGCCAGCGGGGATAAACCGCCGTCAAACAGTATCACCGCGTTAACGCCCGCGAGTTCCCCGCGCCAGCGGGGATAAACCGCCACACACGTCGAGCTGGTGGGGGTTAATGCTGAGTTCCCCGCGCCAGCGGGGATAAACCGACACCTCTACTGACGTTCCTGAACAAGAAGATGAGTTCCCCGCGCCAGCGGGGATAAACCGAAACCGGACGAGGGCGCGCTAAAACGTGATTAGAGTTCCCCGCGCCAGCGGGGATAAACCGCCTCTCAATTTGTAACGTCTGCAATGTCAGGCGAGTTCCCCGTGCCAGCGGGGATAAACCA

>NC_018658|2|2|1161011-1161831|PILER-CR
GAGTTCCCCGCGCCAGCGGGGATAAACC	AGGAACTGGCGCTGCTGGAGCAAAACCCGGTAT
GAGTTCCCCGCGCCAGCGGGGATAAACC	GAAAAGGGCCGCATTGACGGCCCTGTGTTATCG
GAGTTCCCCGCGCCAGCGGGGATAAACC	GTTAGCTGTTAGCCAAACATGTCGACCTGTTTG
GAGTTCCCCGCGCCAGCGGGGATAAACC	GGGGTGGCGGTGGTGCTGTAATTCACACCGGTA
GAGTTCCCCGCGCCAGCGGGGATAAACC	GTATTCCCCCAGTCACCCCCGCCACCAAAATCA
GAGTTCCCCGCGCCAGCGGGGATAAACC	GATTTTTCAGACTCATCAAAATAATCCTTTAAT
GAGTTCCCCGCGCCAGCGGGGATAAACC	GCATTGCCTTTGCAGCGTCTTTCCGATCATTCA
GAGTTCCCCGCGCCAGCGGGGATAAACC	GAACGTGAGATACGCCTCCCAGCGGCGCTCGGT
GAGTTCCCCGCGCCAGCGGGGATAAACC	GCCGTCAAACAGTATCACCGCGTTAACGCCCGC
GAGTTCCCCGCGCCAGCGGGGATAAACC	GCCACACACGTCGAGCTGGTGGGGGTTAATGCT
GAGTTCCCCGCGCCAGCGGGGATAAACC	GACACCTCTACTGACGTTCCTGAACAAGAAGAT
GAGTTCCCCGCGCCAGCGGGGATAAACC	GAAACCGGACGAGGGCGCGCTAAAACGTGATTA
GAGTTCCCCGCGCCAGCGGGGATAAACC	GCCTCTCAATTTGTAACGTCTGCAATGTCAGGC
GAGTTCCCCGTGCCAGCGGGGATAAACC

>NC_018658|2|1|1161011-1161832|CRISPRCasFinder
GAGTTCCCCGCGCCAGCGGGGATAAACCA	GGAACTGGCGCTGCTGGAGCAAAACCCGGTAT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AAAAGGGCCGCATTGACGGCCCTGTGTTATCG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTAGCTGTTAGCCAAACATGTCGACCTGTTTG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGGTGGCGGTGGTGCTGTAATTCACACCGGTA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TATTCCCCCAGTCACCCCCGCCACCAAAATCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATTTTTCAGACTCATCAAAATAATCCTTTAAT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CATTGCCTTTGCAGCGTCTTTCCGATCATTCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AACGTGAGATACGCCTCCCAGCGGCGCTCGGT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCGTCAAACAGTATCACCGCGTTAACGCCCGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCACACACGTCGAGCTGGTGGGGGTTAATGCT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ACACCTCTACTGACGTTCCTGAACAAGAAGAT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AAACCGGACGAGGGCGCGCTAAAACGTGATTA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCTCTCAATTTGTAACGTCTGCAATGTCAGGC
GAGTTCCCCGTGCCAGCGGGGATAAACCA

>NC_018658|2|1|1161011-1161832|CRT
GAGTTCCCCGCGCCAGCGGGGATAAACCA	GGAACTGGCGCTGCTGGAGCAAAACCCGGTAT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AAAAGGGCCGCATTGACGGCCCTGTGTTATCG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTAGCTGTTAGCCAAACATGTCGACCTGTTTG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGGTGGCGGTGGTGCTGTAATTCACACCGGTA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TATTCCCCCAGTCACCCCCGCCACCAAAATCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATTTTTCAGACTCATCAAAATAATCCTTTAAT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CATTGCCTTTGCAGCGTCTTTCCGATCATTCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AACGTGAGATACGCCTCCCAGCGGCGCTCGGT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCGTCAAACAGTATCACCGCGTTAACGCCCGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCACACACGTCGAGCTGGTGGGGGTTAATGCT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ACACCTCTACTGACGTTCCTGAACAAGAAGAT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AAACCGGACGAGGGCGCGCTAAAACGTGATTA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCTCTCAATTTGTAACGTCTGCAATGTCAGGC
GAGTTCCCCGTGCCAGCGGGGATAAACCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_018658.1\|WP_001164557.1\|1163975_1165253_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
NC_018658.1\|WP_000186450.1\|1147604_1150361_-\|two-component-sensor-histidine-kinase-BarA	unknown	unknown	gnl\|CDD\|236848
NC_018658.1\|WP_001130266.1\|1171073_1171649_-\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
NC_018658.1\|WP_000039681.1\|1162470_1163949_-\|kinase	unknown	unknown	gnl\|CDD\|212662
NC_018658.1\|WP_000581937.1\|1154078_1154327_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NC_018658.1\|WP_001199973.1\|1159999_1160671_+\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NC_018658.1\|WP_000254745.1\|1154326_1154662_+\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NC_018658.1\|WP_000046785.1\|1150417_1151719_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291
NC_018658.1\|WP_000226815.1\|1151766_1154001_+\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797
NC_018658.1\|WP_001387010.1\|1171916_1173188_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
NC_018658.1\|WP_000147666.1\|1167902_1169312_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NC_018658.1\|WP_001299097.1\|1170065_1170926_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
NC_018658.1\|WP_001288227.1\|1159720_1159861_-\|hypothetical-protein	unknown	unknown	unknown
NC_018658.1\|WP_001299652.1\|1169289_1170069_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NC_018658.1\|WP_000021321.1\|1165571_1166357_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NC_018658.1\|WP_000210878.1\|1155751_1157389_+\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NC_018658.1\|WP_000059312.1\|1166426_1167881_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NC_018658.1\|WP_000036723.1\|1157476_1158775_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NC_018658.1\|WP_000109532.1\|1171665_1171926_-\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
NC_018658.1\|WP_001071648.1\|1154732_1155524_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569

Protein	Function_ID	Function_description	E-value
NC_018658.1\|WP_001164557.1\|1163975_1165253_-\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	4.01972e-29
NC_018658.1\|WP_000186450.1\|1147604_1150361_-\|two-component-sensor-histidine-kinase-BarA	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	0
NC_018658.1\|WP_001130266.1\|1171073_1171649_-\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	5.83077e-88
NC_018658.1\|WP_000039681.1\|1162470_1163949_-\|kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	5.94468e-108
NC_018658.1\|WP_000581937.1\|1154078_1154327_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
NC_018658.1\|WP_001199973.1\|1159999_1160671_+\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.98248e-155
NC_018658.1\|WP_000254745.1\|1154326_1154662_+\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	2.42227e-74
NC_018658.1\|WP_000046785.1\|1150417_1151719_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0
NC_018658.1\|WP_000226815.1\|1151766_1154001_+\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NC_018658.1\|WP_001387010.1\|1171916_1173188_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	7.53866e-125
NC_018658.1\|WP_000147666.1\|1167902_1169312_+\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.50431e-51
NC_018658.1\|WP_001299097.1\|1170065_1170926_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	7.42017e-90
NC_018658.1\|WP_001299652.1\|1169289_1170069_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	1.56693e-62
NC_018658.1\|WP_000021321.1\|1165571_1166357_+\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.84461e-140
NC_018658.1\|WP_000210878.1\|1155751_1157389_+\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NC_018658.1\|WP_000059312.1\|1166426_1167881_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.25325e-82
NC_018658.1\|WP_000036723.1\|1157476_1158775_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NC_018658.1\|WP_000109532.1\|1171665_1171926_-\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	3.6328e-41
NC_018658.1\|WP_001071648.1\|1154732_1155524_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160

>NC_018658.1|WP_001199973.1|1159999_1160671_+|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NC_018658.1|WP_001288227.1|1159720_1159861_-|hypothetical-protein
MSEENKENGFNHVKTFTKIIFIFSVLVFNDNESKITDAAVNLFIQI
>NC_018658.1|WP_000036723.1|1157476_1158775_+|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NC_018658.1|WP_000210878.1|1155751_1157389_+|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NC_018658.1|WP_001071648.1|1154732_1155524_+|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NC_018658.1|WP_000254745.1|1154326_1154662_+|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPYTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NC_018658.1|WP_000581937.1|1154078_1154327_+|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>NC_018658.1|WP_000226815.1|1151766_1154001_+|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>NC_018658.1|WP_000046785.1|1150417_1151719_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKALFIPGLLPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHEVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILVPKLEALLPKVRACLGSLQVMRHLGHVELVQATSGTLMILRHTAPLSSADREKLERFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLAKQAASVVGVEGVPALVEKGQQNARLNGLQNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
>NC_018658.1|WP_000186450.1|1147604_1150361_-|two-component-sensor-histidine-kinase-BarA
MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDAGASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFHLDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYIALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYSPTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKLKQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKLIGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPEVNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGLVDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREASKILG
>NC_018658.1|WP_000039681.1|1162470_1163949_-|kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTLAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWTWSEDAAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASSVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNVDSIQSWSNA
>NC_018658.1|WP_001164557.1|1163975_1165253_-|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQFSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALAMVIVFTFLLFQKIRTADSAPAMASSK
>NC_018658.1|WP_000021321.1|1165571_1166357_+|SDR-family-oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>NC_018658.1|WP_000059312.1|1166426_1167881_+|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREVMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>NC_018658.1|WP_000147666.1|1167902_1169312_+|MFS-transporter
MTGRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>NC_018658.1|WP_001299652.1|1169289_1170069_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAQGKSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPEFVARHIAEWQHQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFITLEQRTEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP
>NC_018658.1|WP_001299097.1|1170065_1170926_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTEKRPLCLSLARQAGAAKNATLPSGMQQLNIVPGALPDWLVSTEDLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEALVTNIHADCQ
>NC_018658.1|WP_001130266.1|1171073_1171649_-|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISNIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NC_018658.1|WP_000109532.1|1171665_1171926_-|ferredoxin-family-protein
MSVARNLWRVADAPHIVPADSVERQTAERLISACPAGLFSLTPEGDLRIDYRSCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>NC_018658.1|WP_001387010.1|1171916_1173188_-|FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARSGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERCITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLFWHHLRRHGLWHLAGDVIRSLRCL

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Crispr_ID: NC_018658_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018658_3

1188881-1188970

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder

1 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NC_018658_3

>merge|NC_018658|3|1188881-1188970|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCGCCAAAGAAGAACAACGAGCCAACTGGTTTCAGGTGTTCCCCGCGCCAGCGGGGATAAACCG

>NC_018658|3|2|1188881-1188970|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCAAAGAAGAACAACGAGCCAACTGGTTTCAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_018658.1\|WP_001246104.1\|1193332_1193656_+\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NC_018658.1\|WP_001219242.1\|1194889_1195369_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NC_018658.1\|WP_001295182.1\|1196395_1197157_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NC_018658.1\|WP_001084093.1\|1183022_1184585_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NC_018658.1\|WP_000085069.1\|1186195_1186942_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NC_018658.1\|WP_000568956.1\|1195365_1196415_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NC_018658.1\|WP_000029329.1\|1184581_1185118_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|274193
NC_018658.1\|WP_000063179.1\|1188490_1188784_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NC_018658.1\|WP_000246138.1\|1194179_1194890_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NC_018658.1\|WP_001300563.1\|1178759_1179872_+\|IS4-like-element-IS421-family-transposase	unknown	unknown	gnl\|CDD\|376573
NC_018658.1\|WP_001090348.1\|1191250_1192678_+\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NC_018658.1\|WP_000956458.1\|1178530_1178683_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NC_018658.1\|WP_000517476.1\|1193849_1194161_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NC_018658.1\|WP_001233956.1\|1180225_1182925_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_018658.1\|WP_000206435.1\|1185129_1186185_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NC_018658.1\|WP_000490426.1\|1189051_1190089_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NC_018658.1\|WP_000372108.1\|1190340_1191249_+\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NC_018658.1\|WP_000281434.1\|1186923_1187574_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NC_018658.1\|WP_000144875.1\|1187570_1188491_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NC_018658.1\|WP_001173673.1\|1192677_1193283_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661

Protein	Function_ID	Function_description	E-value
NC_018658.1\|WP_001246104.1\|1193332_1193656_+\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
NC_018658.1\|WP_001219242.1\|1194889_1195369_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NC_018658.1\|WP_001295182.1\|1196395_1197157_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NC_018658.1\|WP_001084093.1\|1183022_1184585_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NC_018658.1\|WP_000085069.1\|1186195_1186942_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	4.67461e-49
NC_018658.1\|WP_000568956.1\|1195365_1196415_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NC_018658.1\|WP_000029329.1\|1184581_1185118_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|274193	TIGR02548, CRISPR_system_Cascade_subunit_CasB, CRISPR type I-E/ECOLI-associated protein CasB/Cse2. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It was designated Cse2 originally, and renamed CasB based on its characterization in the CASCADE complex.	1.12087e-29
NC_018658.1\|WP_000063179.1\|1188490_1188784_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	3.5781e-65
NC_018658.1\|WP_000246138.1\|1194179_1194890_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
NC_018658.1\|WP_001300563.1\|1178759_1179872_+\|IS4-like-element-IS421-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	3.16058e-15
NC_018658.1\|WP_001090348.1\|1191250_1192678_+\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NC_018658.1\|WP_000956458.1\|1178530_1178683_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NC_018658.1\|WP_000517476.1\|1193849_1194161_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NC_018658.1\|WP_001233956.1\|1180225_1182925_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.60551e-175
NC_018658.1\|WP_000206435.1\|1185129_1186185_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	8.81938e-155
NC_018658.1\|WP_000490426.1\|1189051_1190089_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NC_018658.1\|WP_000372108.1\|1190340_1191249_+\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NC_018658.1\|WP_000281434.1\|1186923_1187574_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	5.16907e-91
NC_018658.1\|WP_000144875.1\|1187570_1188491_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.70125e-157
NC_018658.1\|WP_001173673.1\|1192677_1193283_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148

>NC_018658.1|WP_000063179.1|1188490_1188784_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGKNRRIPVDLDGLRLVSFLPVDNQ
>NC_018658.1|WP_000144875.1|1187570_1188491_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLINKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRG
>NC_018658.1|WP_000281434.1|1186923_1187574_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQARPAESETFTIECRPFVSELRTGQSLCFNLRANPTICKAGKRHDLLMEAKRQVKGQAEGRDIWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENTRQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEA
>NC_018658.1|WP_000085069.1|1186195_1186942_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSDPELLSAIISRRDYYTDAWWMVAVATTADAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNACDALCNAYQQYQDHFHKLKVSLPKLQDECWWEGKHEGLVASKILRRRDVPLNRQQWLFGERTVNQGPWLSKEEPCTSQE
>NC_018658.1|WP_000206435.1|1185129_1186185_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEDKKAIEWSAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRTPKEEDLALLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQSSEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA
>NC_018658.1|WP_000029329.1|1184581_1185118_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWHEELQEKRGERASLRRSTTVNDVCLTDGFRLFLKNRQIKWQDEPEWRITALALIAAVSANVKAIDERQPFAAQLAAVMSKGRFTRLSAVKTPDELLRQLRRAVRLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQNQ
>NC_018658.1|WP_001084093.1|1183022_1184585_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAAWQFLLGLLQTSFAPKNHGRWDDIWEDGLEAEKLREALLSLEHAFQFGADSPSFMQDFEALKGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCPHCSALALFSLQLNAPSGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKLWPNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTHDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQSDALLSLMTTKNYGANYAMWQHPLTPYRIPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLKKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADELLGKWQKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>NC_018658.1|WP_001233956.1|1180225_1182925_+|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQESARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGRPPDRMDELDNFLPEDKAAARDFLLAIKALFPRIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGSSTRFFPRVAQAMDIKHYWQKALVQAQNALTVFPPKAETAPFTGINTLFPFIENPTPLQQKVLDLDISQPGPQLFILEDVTGAGKTEAALILAHRLIAAGKAHGLFFGLPTMATANAMYDRLVKTWLSFYSPESRPSLVLAHSARTLMDRFNESLWSGDLIGSEEPDEQAFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGAEGQQEAPLLGKDDYPWLTHVTKIDVHSHRVATRKEVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDAIQVYRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKYCSLQRASQVIVCTQVIEQSVDIDLDEMISDLAPIDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDAPGDEWFGSAMRNSAYVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRARAKKYVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIDGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLLEGDAFRQWCVEQRQDPEMANVILVTDDESCGYSAREGLIGKVG
>NC_018658.1|WP_001300563.1|1178759_1179872_+|IS4-like-element-IS421-family-transposase
MNYSHDNWSAILAHIGKPEELDTSARNAGALTRRREIRDAATLLRLGLAYGPGGMSLREVTAWAQLHDVATLSDVALLKRLRNAADWFGILAAQTLAVRAAVTGCTSGKRLRLVDGTAISAPGGGSAEWRLHMGYDPHTCQFTDFELTDSRDAERLDRFAQTADEIRIADRGFGSRPECIRSLAFGEADYIVRVHWRGLRWLTAEGMRFDMMGFLRGLDCGKNGETTVMIGNSGNKKAGAPFPARLIAVSLPPEKALISKTRLLSENRRKGRVVQAETLEAAGHVLLLTSLPEDEYSAEQVADCYRLRWQIELAFKRLKSLLHLDALRAKEPELAKAWIFANLLAAFLIDDIIQPSLDFPPRSAGSEKKN
>NC_018658.1|WP_000956458.1|1178530_1178683_+|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NC_018658.1|WP_000490426.1|1189051_1190089_-|alkaline-phosphatase-isozyme-conversion-aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NC_018658.1|WP_000372108.1|1190340_1191249_+|sulfate-adenylyltransferase-subunit-CysD
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NC_018658.1|WP_001090348.1|1191250_1192678_+|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAEQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>NC_018658.1|WP_001173673.1|1192677_1193283_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NC_018658.1|WP_001246104.1|1193332_1193656_+|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NC_018658.1|WP_000517476.1|1193849_1194161_+|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NC_018658.1|WP_000246138.1|1194179_1194890_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NC_018658.1|WP_001219242.1|1194889_1195369_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NC_018658.1|WP_000568956.1|1195365_1196415_+|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPELSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NC_018658.1|WP_001295182.1|1196395_1197157_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW

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Crispr_ID: NC_018658_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018658_4

2442626-2442749

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_018658_4

>merge|NC_018658|4|2442626-2442749|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>NC_018658|4|3|2442626-2442749|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NC_018658.1\|WP_001182363.1\|2448068_2449280_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|182924
NC_018658.1\|WP_000212657.1\|2442185_2442491_-\|monooxygenase	unknown	unknown	gnl\|CDD\|182975
NC_018658.1\|WP_001070230.1\|2434713_2435340_+\|ferredoxin-like-protein	unknown	unknown	gnl\|CDD\|182135
NC_018658.1\|WP_000269501.1\|2449392_2450325_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182948
NC_018658.1\|WP_001299088.1\|2437475_2438114_+\|YdhW-family-putative-oxidoreductase-system-protein	unknown	unknown	gnl\|CDD\|182160
NC_018658.1\|WP_000098911.1\|2446629_2447778_-\|cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|183282
NC_018658.1\|WP_000190982.1\|2450321_2451347_-\|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl\|CDD\|236739
NC_018658.1\|WP_000528342.1\|2434048_2434258_+\|fumarate-hydratase-FumD	unknown	unknown	gnl\|CDD\|182359
NC_018658.1\|WP_001273518.1\|2435360_2437463_+\|aldehyde-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|236629
NC_018658.1\|WP_000102278.1\|2451645_2451735_+\|stress-response-protein-YnhF	unknown	unknown	unknown
NC_018658.1\|WP_001174942.1\|2444360_2445734_-\|multidrug-efflux-MATE-transporter-MdtK	unknown	unknown	gnl\|CDD\|234981
NC_018658.1\|WP_000701040.1\|2451900_2453070_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NC_018658.1\|WP_000587560.1\|2439631_2440444_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182159
NC_018658.1\|WP_000493947.1\|2445948_2446590_+\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|183846
NC_018658.1\|WP_001069992.1\|2438842_2439628_+\|thiosulfate-reductase-cytochrome-B-subunit	unknown	unknown	gnl\|CDD\|184968
NC_018658.1\|WP_000534291.1\|2443063_2444320_+\|AIDA-repeat-containing-protein	unknown	unknown	gnl\|CDD\|137602
NC_018658.1\|WP_001349911.1\|2438177_2438846_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|274451
NC_018658.1\|WP_000007283.1\|2453215_2453797_-\|superoxide-dismutase-[Fe]	unknown	unknown	gnl\|CDD\|182534
NC_018658.1\|WP_000716922.1\|2440455_2442060_-\|FAD-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|182134
NC_018658.1\|WP_001295403.1\|2432079_2433492_-\|pyruvate-kinase-PykF	unknown	unknown	gnl\|CDD\|181699

Protein	Function_ID	Function_description	E-value
NC_018658.1\|WP_001182363.1\|2448068_2449280_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
NC_018658.1\|WP_000212657.1\|2442185_2442491_-\|monooxygenase	gnl\|CDD\|182975	PRK11118, PRK11118, putative monooxygenase; Provisional.	1.12003e-64
NC_018658.1\|WP_001070230.1\|2434713_2435340_+\|ferredoxin-like-protein	gnl\|CDD\|182135	PRK09898, PRK09898, ferredoxin-like protein.	6.99609e-140
NC_018658.1\|WP_000269501.1\|2449392_2450325_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0
NC_018658.1\|WP_001299088.1\|2437475_2438114_+\|YdhW-family-putative-oxidoreductase-system-protein	gnl\|CDD\|182160	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein.	1.44183e-120
NC_018658.1\|WP_000098911.1\|2446629_2447778_-\|cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	0
NC_018658.1\|WP_000190982.1\|2450321_2451347_-\|HTH-type-transcriptional-repressor-PurR	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
NC_018658.1\|WP_000528342.1\|2434048_2434258_+\|fumarate-hydratase-FumD	gnl\|CDD\|182359	PRK10292, PRK10292, fumarate hydratase FumD.	2.11502e-34
NC_018658.1\|WP_001273518.1\|2435360_2437463_+\|aldehyde-ferredoxin-oxidoreductase	gnl\|CDD\|236629	PRK09849, PRK09849, putative oxidoreductase; Provisional.	0
NC_018658.1\|WP_001174942.1\|2444360_2445734_-\|multidrug-efflux-MATE-transporter-MdtK	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
NC_018658.1\|WP_000701040.1\|2451900_2453070_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.92383e-98
NC_018658.1\|WP_000587560.1\|2439631_2440444_+\|hypothetical-protein	gnl\|CDD\|182159	PRK09946, PRK09946, hypothetical protein; Provisional.	8.20825e-175
NC_018658.1\|WP_000493947.1\|2445948_2446590_+\|riboflavin-synthase	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	2.24506e-123
NC_018658.1\|WP_001069992.1\|2438842_2439628_+\|thiosulfate-reductase-cytochrome-B-subunit	gnl\|CDD\|184968	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional.	1.73962e-162
NC_018658.1\|WP_000534291.1\|2443063_2444320_+\|AIDA-repeat-containing-protein	gnl\|CDD\|137602	PRK09945, PRK09945, hypothetical protein; Provisional.	0
NC_018658.1\|WP_001349911.1\|2438177_2438846_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|274451	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein. Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport].	7.32003e-76
NC_018658.1\|WP_000007283.1\|2453215_2453797_-\|superoxide-dismutase-[Fe]	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	3.77321e-138
NC_018658.1\|WP_000716922.1\|2440455_2442060_-\|FAD-NAD(P)-binding-protein	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0
NC_018658.1\|WP_001295403.1\|2432079_2433492_-\|pyruvate-kinase-PykF	gnl\|CDD\|181699	PRK09206, PRK09206, pyruvate kinase PykF.	0

>NC_018658.1|WP_000212657.1|2442185_2442491_-|monooxygenase
MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTESEKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA
>NC_018658.1|WP_000716922.1|2440455_2442060_-|FAD-NAD(P)-binding-protein
MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPINCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVIATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVVFNRDNASEKLNITLMSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVVKPASRARRRLSFD
>NC_018658.1|WP_000587560.1|2439631_2440444_+|hypothetical-protein
MIITRADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYTDWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGEIPFCSQFARSDDHARIGCCEDNARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRIANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRTGVRYRLNEQHQFVEC
>NC_018658.1|WP_001069992.1|2438842_2439628_+|thiosulfate-reductase-cytochrome-B-subunit
MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVLGLHALLRARGVKKSVTDYGEKIYLYCKAVRLWHWSNALLFVLLLASGLINHFALVGATAVKSLVAVHEVCGFLLLACWLGFVLINAVGDNGHHYRIRRQGWLERAAKQTRFYLFGIMQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYWLLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH
>NC_018658.1|WP_001349911.1|2438177_2438846_+|4Fe-4S-dicluster-domain-containing-protein
MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDESRCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLAKGFPPICVSACPEHALIFGREDSPEIQAWLQDNKYYQYQLPGAGKPHLYRRFGQHLIKKENV
>NC_018658.1|WP_001299088.1|2437475_2438114_+|YdhW-family-putative-oxidoreductase-system-protein
MNHRDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAEFIRQHSVAGQLVARAVFLSPPYSVAEEELSVLLESIKQNGDYADIACMTGSQDDYYYSTQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEAAIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP
>NC_018658.1|WP_001273518.1|2435360_2437463_+|aldehyde-ferredoxin-oxidoreductase
MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDEVPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQMKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCVAAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKRLNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPPGNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGNTCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYSKGVFKRVLPAEEYAEIHWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWNLGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPLKLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTVSPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRNEHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQRLGLEDIAADLAAHNLLPV
>NC_018658.1|WP_001070230.1|2434713_2435340_+|ferredoxin-like-protein
MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
>NC_018658.1|WP_000528342.1|2434048_2434258_+|fumarate-hydratase-FumD
MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
>NC_018658.1|WP_001295403.1|2432079_2433492_-|pyruvate-kinase-PykF
MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL
>NC_018658.1|WP_000534291.1|2443063_2444320_+|AIDA-repeat-containing-protein
MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDQGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILDGSTVKGDGVTFIVGNINLNGGKLWLITGAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITDASRQTLCNALKLQPDEDGIGATLQPA
>NC_018658.1|WP_001174942.1|2444360_2445734_-|multidrug-efflux-MATE-transporter-MdtK
MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSVIILQRASR
>NC_018658.1|WP_000493947.1|2445948_2446590_+|riboflavin-synthase
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA
>NC_018658.1|WP_000098911.1|2446629_2447778_-|cyclopropane-fatty-acyl-phospholipid-synthase
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIASARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR
>NC_018658.1|WP_001182363.1|2448068_2449280_-|Bcr/CflA-family-multidrug-efflux-MFS-transporter
MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQAIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNHGNAEVAHSESH
>NC_018658.1|WP_000269501.1|2449392_2450325_+|LysR-family-transcriptional-regulator
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRVVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD
>NC_018658.1|WP_000190982.1|2450321_2451347_-|HTH-type-transcriptional-repressor-PurR
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
>NC_018658.1|WP_000102278.1|2451645_2451735_+|stress-response-protein-YnhF
MSTDLKFSLVTTIIVLGLIVAVGLTAALH
>NC_018658.1|WP_000701040.1|2451900_2453070_+|MFS-transporter
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRMSFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS
>NC_018658.1|WP_000007283.1|2453215_2453797_-|superoxide-dismutase-[Fe]
MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFGSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA

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Crispr_ID: NC_018658_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018658_5

3255563-3255654

Orphan

Consensus_repeat	Method
CCACCTTTTTTACCTGCTTCAGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_018658_5

>merge|NC_018658|5|3255563-3255654|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGCGCGCTGCGGGTCATTCTTGAAATTACCCCCGCTGTGCTGTCCACCTTTTTTACCTGCTTCTGATGC

>NC_018658|5|4|3255563-3255654|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGC	GCGCTGCGGGTCATTCTTGAAATTACCCCCGCTGTGCTGT
CCACCTTTTTTACCTGCTTCTGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018658.1\|WP_001299828.1\|3245077_3249040_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|236989
NC_018658.1\|WP_000012452.1\|3265087_3266353_-\|hypothetical-protein	unknown	unknown	unknown
NC_018658.1\|WP_000078907.1\|3268281_3268422_-\|Hok/Gef-family-protein	unknown	unknown	gnl\|CDD\|182063
NC_018658.1\|WP_001326838.1\|3254120_3255449_+\|pyrimidine-utilization-transport-protein-G	unknown	unknown	gnl\|CDD\|132655
NC_018658.1\|WP_001307099.1\|3252194_3252995_+\|pyrimidine-utilization-protein-D	unknown	unknown	gnl\|CDD\|211851
NC_018658.1\|WP_000540391.1\|3266363_3266615_-\|bacteriocin	unknown	unknown	gnl\|CDD\|274783
NC_018658.1\|WP_000455649.1\|3266624_3267071_-\|hypothetical-protein	unknown	unknown	unknown
NC_018658.1\|WP_001028096.1\|3253605_3254100_+\|pyrimidine-utilization-flavin-reductase-protein-F	unknown	unknown	gnl\|CDD\|132654
NC_018658.1\|WP_001001196.1\|3253004_3253595_+\|malonic-semialdehyde-reductase	unknown	unknown	gnl\|CDD\|180040
NC_018658.1\|WP_000455634.1\|3270102_3270381_-\|outer-membrane-protein	unknown	unknown	unknown
NC_018658.1\|WP_001126777.1\|3251800_3252187_+\|pyrimidine-utilization-protein-C	unknown	unknown	gnl\|CDD\|274677
NC_018658.1\|WP_000035558.1\|3267823_3268225_-\|hypothetical-protein	unknown	unknown	unknown
NC_018658.1\|WP_001297176.1\|3250005_3251097_+\|pyrimidine-utilization-protein-A	unknown	unknown	gnl\|CDD\|163355
NC_018658.1\|WP_001301884.1\|3269479_3270097_-\|hypothetical-protein	unknown	unknown	unknown
NC_018658.1\|WP_000191700.1\|3249079_3249718_-\|HTH-type-transcriptional-regulator-RutR	unknown	unknown	gnl\|CDD\|184970
NC_018658.1\|WP_000979516.1\|3244813_3245023_-\|hypothetical-protein	unknown	unknown	unknown
NC_018658.1\|WP_000509489.1\|3267073_3267730_-\|hypothetical-protein	unknown	unknown	unknown
NC_018658.1\|WP_001307708.1\|3251096_3251789_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	unknown	unknown	gnl\|CDD\|163356
NC_018658.1\|WP_000835360.1\|3268654_3269389_-\|Ail/Lom-family-outer-membrane-beta-barrel-protein	unknown	unknown	gnl\|CDD\|115004
NC_018658.1\|WP_000331685.1\|3256636_3265018_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376218

Protein	Function_ID	Function_description	E-value
NC_018658.1\|WP_001299828.1\|3245077_3249040_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|236989	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed.	0
NC_018658.1\|WP_001326838.1\|3254120_3255449_+\|pyrimidine-utilization-transport-protein-G	gnl\|CDD\|132655	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the uracil-xanthine permease family defined by TIGR00801. As well as the The Nucleobase:Cation Symporter-2 (NCS2) Family (TC 2.A.40).	0
NC_018658.1\|WP_001307099.1\|3252194_3252995_+\|pyrimidine-utilization-protein-D	gnl\|CDD\|211851	TIGR03611, RutD, pyrimidine utilization protein D. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the hydrolase, alpha/beta fold family defined by pfam00067.	1.96403e-140
NC_018658.1\|WP_000540391.1\|3266363_3266615_-\|bacteriocin	gnl\|CDD\|274783	TIGR03789, pdsO, proteobacterial sortase system peptidoglycan-associated protein. A newly defined histidine kinase (TIGR03785) and response regulator (TIGR03787) gene pair occurs exclusively in Proteobacteria, mostly of marine origin, nearly all of which contain a subfamily 6 sortase (TIGR03784) and its single dedicated target protein (TIGR03788) adjacent to to the sortase. This protein family shows up in only in those species with the histidine kinase/response regulator gene pair, and often adjacent to that pair. It belongs to the pfam00691 domain family, which is the peptidoglycan-associated region of flagellar motor protein MotB, OmpA (whose N-terminal region forms an outer membrane beta barrel), and peptidoglycan-associated lipoprotein Pal. Its function is unknown. We assign the gene symbol pdsO, for Proteobacterial Dedicated Sortase system OmpA family protein. [Protein fate, Protein and peptide secretion and trafficking].	8.39825e-07
NC_018658.1\|WP_000078907.1\|3268281_3268422_-\|Hok/Gef-family-protein	gnl\|CDD\|182063	PRK09759, PRK09759, type I toxin-antitoxin system toxin HokA.	6.67387e-05
NC_018658.1\|WP_001028096.1\|3253605_3254100_+\|pyrimidine-utilization-flavin-reductase-protein-F	gnl\|CDD\|132654	TIGR03615, flavoprotein_oxidoreductase, pyrimidine utilization flavin reductase protein F. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the flavin reductase family defined by pfam01613. Presumably, this protein recycles the flavin of the RutA luciferase-like oxidoreductase.	8.28716e-106
NC_018658.1\|WP_001001196.1\|3253004_3253595_+\|malonic-semialdehyde-reductase	gnl\|CDD\|180040	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional.	1.45614e-128
NC_018658.1\|WP_001126777.1\|3251800_3252187_+\|pyrimidine-utilization-protein-C	gnl\|CDD\|274677	TIGR03610, RutC, pyrimidine utilization protein C. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the endoribonuclease L-PSP family defined by pfam01042.	6.69692e-84
NC_018658.1\|WP_001297176.1\|3250005_3251097_+\|pyrimidine-utilization-protein-A	gnl\|CDD\|163355	TIGR03612, RutA, pyrimidine utilization protein A. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the luciferase family defined by pfam00296 and is likely a FMN-dependent monoxygenase. [Unknown function, Enzymes of unknown specificity].	0
NC_018658.1\|WP_000191700.1\|3249079_3249718_-\|HTH-type-transcriptional-regulator-RutR	gnl\|CDD\|184970	PRK15008, PRK15008, HTH-type transcriptional regulator RutR; Provisional.	1.12845e-153
NC_018658.1\|WP_001307708.1\|3251096_3251789_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	gnl\|CDD\|163356	TIGR03614, RutB, pyrimidine utilization protein B.	5.84226e-169
NC_018658.1\|WP_000835360.1\|3268654_3269389_-\|Ail/Lom-family-outer-membrane-beta-barrel-protein	gnl\|CDD\|115004	pfam06316, Ail_Lom, Enterobacterial Ail/Lom protein. This family consists of several bacterial and phage Ail/Lom-like proteins. The Yersinia enterocolitica Ail protein is a known virulence factor. Proteins in this family are predicted to consist of eight transmembrane beta-sheets and four cell surface-exposed loops. It is thought that Ail directly promotes invasion and loop 2 contains an active site, perhaps a receptor-binding domain. The phage protein Lom is expressed during lysogeny, and encode host-cell envelope proteins. Lom is found in the bacterial outer membrane, and is homologous to virulence proteins of two other enterobacterial genera. It has been suggested that lysogeny may generally have a role in bacterial survival in animal hosts, and perhaps in pathogenesis.	1.86547e-29
NC_018658.1\|WP_000331685.1\|3256636_3265018_-\|hypothetical-protein	gnl\|CDD\|376218	pfam18799, LPD5, Large polyvalent protein-associated domain 5. This domain is predicted to be an enzymatic alpha beta domain. It often found N-terminal to a metallopeptidase domain in polyvalent proteins. The domain contains a conserved aspartate, lysine, and two arginine residues.	4.69869e-49

>NC_018658.1|WP_001326838.1|3254120_3255449_+|pyrimidine-utilization-transport-protein-G
MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP
>NC_018658.1|WP_001028096.1|3253605_3254100_+|pyrimidine-utilization-flavin-reductase-protein-F
MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHTTPYGLVWFDRSYHALMRPAC
>NC_018658.1|WP_001001196.1|3253004_3253595_+|malonic-semialdehyde-reductase
MNEAVSPGALSTLFTDARTHNGWRETPVSDETLRELYALMKWGPTSANCSPARIVFIRTVEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPLLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQYVDDAFFAGSTLKSNLLINIGYGDSSKLYARLPRLSFEEACGLL
>NC_018658.1|WP_001307099.1|3252194_3252995_+|pyrimidine-utilization-protein-D
MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPSACSSELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL
>NC_018658.1|WP_001126777.1|3251800_3252187_+|pyrimidine-utilization-protein-C
MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLEIIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
>NC_018658.1|WP_001307708.1|3251096_3251789_+|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB
MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
>NC_018658.1|WP_001297176.1|3250005_3251097_+|pyrimidine-utilization-protein-A
MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPALTQEVA
>NC_018658.1|WP_000191700.1|3249079_3249718_-|HTH-type-transcriptional-regulator-RutR
MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKLEVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQHLIFMIWASTQHYADFAPQVEAVTGATLRDEIFFNQTVENVQRIIIEGIRPR
>NC_018658.1|WP_001299828.1|3245077_3249040_+|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGFVREATPREVEQALESAVNNAPIWFATPPVERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGQGETVGAQLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYNRNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
>NC_018658.1|WP_000979516.1|3244813_3245023_-|hypothetical-protein
MMLQLCATMLNVTCVASLKMNEMLIKEIDMTGIKKITQTFSLRQLTFLKGATAKNVRECNLMKNSVAEH
>NC_018658.1|WP_000331685.1|3256636_3265018_-|hypothetical-protein
MAYSEEQRPEAQLGNQNRNSLNIQQPGETDSYEAFFSDPNRWKDNSTSFSLGDVLPTMGKGFAQSVRGTGEMARGLGDAMIQSPVKTGARILNEFSRMGLPGVATVQDIFAGGSRGADEVIDTLPDGKNAVTDTVGKGLKATGKAVSDGAKATDEWLTGKMSPGAVRALNTPMTEGYNDSAVWVAKGVNLIGALVPDMVAGGVARKVGDVTLRKMLTAGLEKKYIAAGMQPERATALAAEAVDKKMPDLFQAGLITHSTVSAQGQSAMAAADAVLNADYSELAQSPKFQQTFLSIDADPQHAQLTDRQKMDLAKERVADEVRAQLATDPELLAVNAMAAKLGDAQLFNLVTRGTAKTVKSGIVRNATAQGAINAAQGGYSRYQENTALRETAGMDVSPWEGVADATIEGAALGAAMGAPFGAVAGYRGRRQAAEETAMRDAETVQQDDAAPQPESVDPVAQQRESMQGMNREQLLEQYADADMATEGDASAAHRREAASQLLNELDEQTKRQAVMNELKAKPRSELLEEYRRLSQKEGRTETEEQQFQAIREVIRPQQEVTPEAQSQPENAEDGNGSIYPTVRFRDPNEVRIEINGNGASRPAERIEKVRPDNRYFTDEKSAMGSDVFRNAAATGLKPSVVKKGENQYAVEMDNPAFSEDVATETINTLADRERIADADPMEQPAFMRDPRFRGFTGDDTEVQARLARGNAPTAEELVRSQMAEGDAGPTAQELTERPRLPAPGDIHPGQGYPLPGEVARTPDENQAGRGGRFTTTGEVKGQSFQKGQAPAPENAAGRQGETLEGEMVRRGLPSPDAQNATAPVREGLPAPDITHNVRMPQPDQLPRTVRNSLPELAQQAEVRRQAGGNRDIPQPETIAPESETTVSTDREATVRGGEVRGKKIEDFGEEIKGAAKHRYAQLAETLGKTLEDRDYATQPLSKLFPKPDYAKLASEGADADTLAMIALYRSDIPAKTKHNTAGWGESVKKVRHSVSEMLNGTVSAKRLAEWMEGRMPSRYADTWQLLRTLPPSQMDKASAYRVVSGVYQAAGGKRYDPPQKLYSLRNKDNKGTNLFFSESRDELLTKAKVWFAELEEKSQAKGDEKTAPSPDDKIRFDVYRNTRSGDIFIAYGKNKMRVRGGFKSASDARKYIDSHRDELVRHVKEMREISREEQRNATNRDRTGPERRKGDVSPEQFSDAFGFRGVQFGNYVEGPRRQADLNRAYDSLHDLAEVLNVPTKALSLNGRLGLAFGARGKGKAAAHYEPGEVAINLTKGNGPGALAHEWFHSLDNYFGRYDVSNDGKITSGGDFMTEAQRVRRIFKDGRYVDAEYPVRQEVYDAFKGVIQAIKNSDMPRRSVLLDEVRSKPYWSTDVEMAARAFERYVQDKARMAGVENDYLVNIRKAPEHNTDNTWAYPTNAELDGGIREAFDHLFRTLKTRETDKGVAFYSRKGVTRTPEGNLISDVNRSAEAKGSPVPQVEAVARGVMSGIKDSDLKVRVVKSQKEAEALAGELFDGYGRVHAFYRPDKREIVLVADNIPDGRTVREKLRHEIIHHAMEHVVTPAEYQTIIKTVLKTRDSDNVTIREAWRKVDASYGKESPEVQAGEFLAHMAEKQPNKFVAAWERVVALVKGVLRRTGLLKPTELNDIRLVRETIRTLGQRVREGYTPREDGAGASSQYSRSGKRDPFKVPEGEGERYRDDLARMMKSLRTTDLTVNIGRTPPVLRHLGAPDLPLVISRDTVRKATNGVKHVVPMDVIERLPELMHDPDAIYRSATERNAVVMLLDAVDKNGDPVVSAVHMKAVRSRLEINKVASVYGTENGKKLKSMEMTGLTLYRREKLSRDNLLHRGLQLPKGEHSYRGSADKILYPEDIRKGPYYSRTSSLTPEETIASRFVRQMQDKFQVLKAVQENIRKTGGKVDDSNNAYMAEELFHGKAENDLNVMKERYVQPLAKLLADYKIAQADLDEYLYARHAPERNAHIAKINPKMPDGGSGMTNAEAAEIMQRVRNSGKQAQYDRLAGIIDDMLARRRELIREAGLEENGVVDAWQNAYRYYVPLKGQDVDGVVSLPRTGKGFTIGGRESRQAMGRASRAQSPSTQAIQDLSESLIRHRKNEVGNAFLKLVQDNPDKDYWQVFTDDRPDTMRTIAERKDQETGETIREVVERPVPMAMMADRYFTTKKNGKTYYIKLHDPRLMRAMKSMGPETSNAFVRTLGKVNRFLATVNTSYNPEFLVSNFIRDVQTAVMNLKAEQGRSDGKLKGLDNLSALAVVKDSRSAMSAVYASLRGKTLTGKGAQWQKVWKEFVEDGGKTGWFNMGDLEGQQKEMDRLVSLAKGGWKGQSIGAWNSFLNLVEDANGAVENALRLSAYKHARDAGLSRQQAASLAKNMTVNFNRRGEQGALMNSLYMFANASIQGTANLVRTLGHLNGDGPLLERLRWKNLNVPQKIALAAVGAGYLLGSLNRSVAGEDDDGVNWYDKVPSHVKERNLVIMKSVFGGKAGEYWSIPLPYGYNVFFLLGHTAEGVAAGDLTASRAAGNVVGGVLGAFSPIGSETSETLSGALLKNAAPTILRPFANLAMNENFMGAQIYQENMPFGTPKPDSQLGRRSTPEAYKAFASWLNAFSGGSQYRSGAVDITPESLKYWVDYISGGTGRFISKTTDAAVKSLNGIDIPEQQVPFLGKISGEVMPYVDQQKMYDRMTEVAQYHAELKSLTGAERTAFIDENNGKLSMNGLMQDTRKRLKDLRKQRDAIYADSTLSLAQQSAMVKSVERDMKIAVDRFNREYNKKVGVD
>NC_018658.1|WP_000012452.1|3265087_3266353_-|hypothetical-protein
MSGFAQGLLAGFSTVDQAMTRRKELGLREAQLARQQKNNERDFEFAQSQFEHNKNVDQRNFDYRAKVDDRNYALKEREFNANQNYRNASLGMEQQRLQLQKYNQRRLEYNDMIAHSQPLMEALGKAIEAGDQEAATRLFGQLPKGHPLILMSNEGYAAKAGQAVINLQKIFGDKPDMAIDSLNTPENLDVLSGVFAPELQQRIGMPDSTGEKTIKEARIGSIVPAQQEGYVLIGLDLTYSDGSTAHKPVTEYGSAHPDDQTVLAIPVDKAIAQVRDRSKFAEISKNYGYFMPKQQGLSLKELQKGASNVAADAIKNGGNAQAAVDEYYAATGSQPHQQKIQQQKLQQQVINWAGDDPDKLSFARNVAARQPEMLEPQNQKLLENGYANFLRIQKARGEQARDESASSASQFIRGLKQNYAQ
>NC_018658.1|WP_000540391.1|3266363_3266615_-|bacteriocin
MGYGLLDIANQSRREALQGISDADRRREEIEAANKQMAAQQKAQNKQNIGTGIGTGAAIGASVGGPVGAVAGAVIGGIAGSLF
>NC_018658.1|WP_000455649.1|3266624_3267071_-|hypothetical-protein
MEYGKYETLARYGYTGAARPQGDWQTSAALTRQQYDDWRTRYLPRVARLADLGENNSLMNAQLARVGGLATSSLRTAQMAQDNQMARYGVNRPDNPDSNTLGLRNALAIAGAKNGIREAEQDRQMNILTGASAPARQKLSVGGQLVAA
>NC_018658.1|WP_000509489.1|3267073_3267730_-|hypothetical-protein
MGGSKGGGDTKVKPTAAQIAQEEVAWKGWQDYKNILRPAEDNFMEKVDDLNSEQQYDNIAGTTNLGYQKQFGEARRELAGNLAQSGVDPSSGRFNAVMNANQSDQVTGQIDTTTRGQVSQADKYVAGLQDVAALGSGQKADALQSFNSLADSSLAKAKSDAQAAFTKQQGRASLVGAGLGAAGAYAMHKAGGSGGSGGAKTPGTGANAIQHQAQNWRL
>NC_018658.1|WP_000035558.1|3267823_3268225_-|hypothetical-protein
MAPVSGERMNDKILWYMQRVVRNSRNPEFMNEVKDACLKKQAFCFEAPDGFLVLRSVLSADGIPYVLVLLGVCTGSNSVERYLPEVKTLTHLAGGRWAEFHTARRGFIRLGKRLGFERMPDDEDGFMVFRIAV
>NC_018658.1|WP_000078907.1|3268281_3268422_-|Hok/Gef-family-protein
MSQKSLITVTICMTVIFTIWMLHGSLCEFRLNLWGAEFAAFLQCKQ
>NC_018658.1|WP_000835360.1|3268654_3269389_-|Ail/Lom-family-outer-membrane-beta-barrel-protein
MKSIATLVVCAISGIACVNLSAHAAEGEHTISLGYAHFQFPGLKDFVKDATAHNRETFSHFVNRNYFSSLGEYTDGRVSGYEGKDKNPQGINIRYRYEITDDFGVITSFTWTRSLTNSQTFIDVQSADHTRKIKNPAASARTDIRANYWSLLAGPSWRVNQYMSLYAMAGMGVAKVSADLKIKDNINSSGGFSESNSTKKTSLAWAAGAQFNLNESVTLDVAYEGSGSGDWRTSGVTAGIGLKF
>NC_018658.1|WP_001301884.1|3269479_3270097_-|hypothetical-protein
MYGLSIMKPDGSVWISPGFTPQCLINKGTIPATEKSFFKTSIPSGKSCFFFIRTEKKADVMYTHEQIDGYHALRLHVIVRGTNPGVTTVYAFANMVTPPSEYGIAMYNPDGEMIYHGEMMLLDAKLIPVDIKFEKDLGYPCAIMPALVGYYNWKRTPYDRPIYTTSTGATGNKIYSCEHYSGGATWDIRKPYIDKVLVINTSVYD
>NC_018658.1|WP_000455634.1|3270102_3270381_-|outer-membrane-protein
MEYGFAIYNRNNVNVTGVLTPVFFLDRFTAESGSKTYTNKPDGKSLQAVCCLFPWNNVFADRKVPKITINDNTVTWSNLEQGMGSYIYTFWG

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Crispr_ID: NC_018658_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018658_6

3616023-3616136

Orphan

Consensus_repeat	Method
TTTTTTTACCTGATTCGGGTAAA	PILER-CR

2 spacers

The CRISPR arrays of NC_018658_6

>merge|NC_018658|6|3616023-3616136|PILER-CR
TTTACCTGATTCGGGTAAACGCCTTTACCTGATGTGGGTAAACTTTTTTTACCTGATTCAGGTAAATTTACCTCTTTCAGGTAAACTTTATTTTTCTTACCTGATTCGGGTAAT

>NC_018658|6|3|3616023-3616136|PILER-CR
TTTACCTGATTCGGGTAAACGCC	TTTACCTGATGTGGGTAAACTTTT
TTTACCTGATTCAGGTAAATTTA	CCTCTTTCAGGTAAACTTTATTTTT
CTTACCTGATTCGGGTAAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_018658.1\|WP_000682318.1\|3620847_3621030_+\|DUF1317-domain-containing-protein	unknown	unknown	gnl\|CDD\|284449
NC_018658.1\|WP_000145901.1\|3614559_3614862_-\|protein-ren	unknown	unknown	unknown
NC_018658.1\|WP_000548541.1\|3621002_3621194_+\|DUF1382-family-protein	unknown	unknown	gnl\|CDD\|369224
NC_018658.1\|WP_000788812.1\|3614858_3615560_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369163
NC_018658.1\|WP_000971074.1\|3610742_3610883_-\|YlcG-family-protein	unknown	unknown	unknown
NC_018658.1\|WP_001204791.1\|3610273_3610657_-\|antitermination-protein-QuuD	unknown	unknown	gnl\|CDD\|368957
NC_018658.1\|WP_000774504.1\|3611237_3611528_-\|DUF1364-domain-containing-protein	unknown	unknown	gnl\|CDD\|377777
NC_018658.1\|WP_001053034.1\|3611690_3612146_-\|DNA-base-flipping-protein-YbcN	unknown	unknown	gnl\|CDD\|182057
NC_018658.1\|WP_000100847.1\|3619388_3620174_+\|phage-recombination-protein-Bet	unknown	unknown	gnl\|CDD\|273871
NC_018658.1\|WP_001067458.1\|3617181_3617412_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|374243
NC_018658.1\|WP_000233576.1\|3618804_3619011_+\|phage-encoded-cell-division-inhibitor-protein	unknown	unknown	gnl\|CDD\|236900
NC_018658.1\|WP_000995433.1\|3619086_3619383_+\|host-nuclease-inhibitor-protein-Gam	unknown	unknown	gnl\|CDD\|368728
NC_018658.1\|WP_000186833.1\|3620170_3620851_+\|YqaJ-viral-recombinase-family-protein	unknown	unknown	gnl\|CDD\|378216
NC_018658.1\|WP_072147432.1\|3612142_3612244_-\|hypothetical-protein	unknown	unknown	unknown
NC_018658.1\|WP_000224912.1\|3611520_3611691_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182029
NC_018658.1\|WP_000188870.1\|3621270_3621486_+\|hypothetical-protein	unknown	unknown	unknown
NC_018658.1\|WP_001182903.1\|3616572_3617112_-\|toxin-YdaT-domain-containing-protein	unknown	unknown	gnl\|CDD\|368819
NC_018658.1\|WP_000338663.1\|3613168_3613408_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371129
NC_018658.1\|WP_001391403.1\|3612340_3612592_-\|hypothetical-protein	unknown	unknown	unknown
NC_018658.1\|WP_000858975.1\|3617517_3618207_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225484

Protein	Function_ID	Function_description	E-value
NC_018658.1\|WP_000682318.1\|3620847_3621030_+\|DUF1317-domain-containing-protein	gnl\|CDD\|284449	pfam07026, DUF1317, Protein of unknown function (DUF1317). This family consists of several hypothetical bacterial and phage proteins of around 60 residues in length. The function of this family is unknown.	4.99888e-34
NC_018658.1\|WP_000774504.1\|3611237_3611528_-\|DUF1364-domain-containing-protein	gnl\|CDD\|377777	pfam07102, DUF1364, Protein of unknown function (DUF1364). This family consists of several bacterial and phage proteins of around 95 residues in length. The function of this family is unknown.	5.39804e-47
NC_018658.1\|WP_000548541.1\|3621002_3621194_+\|DUF1382-family-protein	gnl\|CDD\|369224	pfam07131, DUF1382, Protein of unknown function (DUF1382). This family consists of several hypothetical Escherichia coli and bacteriophage lambda-like proteins of around 60 residues in length. The function of this family is unknown. Structural modelling suggests this domain may bind nucleic acids.	2.3749e-22
NC_018658.1\|WP_000788812.1\|3614858_3615560_-\|hypothetical-protein	gnl\|CDD\|369163	pfam06992, Phage_lambda_P, Replication protein P. This family consists of several Bacteriophage lambda replication protein P like proteins. The bacteriophage lambda P protein promoters replication of the phage chromosome by recruiting a key component of the cellular replication machinery to the viral origin. Specifically, P protein delivers one or more molecules of Escherichia coli DnaB helicase to a nucleoprotein structure formed by the lambda O initiator at the lambda replication origin.	1.65476e-82
NC_018658.1\|WP_001204791.1\|3610273_3610657_-\|antitermination-protein-QuuD	gnl\|CDD\|368957	pfam06530, Phage_antitermQ, Phage antitermination protein Q. This family consists of several phage antitermination protein Q and related bacterial sequences. Antiterminator proteins control gene expression by recognising control signals near the promoter and preventing transcriptional termination which would otherwise occur at sites that may be a long way downstream.	1.03414e-70
NC_018658.1\|WP_000233576.1\|3618804_3619011_+\|phage-encoded-cell-division-inhibitor-protein	gnl\|CDD\|236900	PRK11354, kil, FtsZ inhibitor protein; Reviewed.	6.0586e-14
NC_018658.1\|WP_001053034.1\|3611690_3612146_-\|DNA-base-flipping-protein-YbcN	gnl\|CDD\|182057	PRK09741, PRK09741, hypothetical protein; Provisional.	7.55001e-95
NC_018658.1\|WP_000100847.1\|3619388_3620174_+\|phage-recombination-protein-Bet	gnl\|CDD\|273871	TIGR01913, Uncharacterized_protein_UU154, phage recombination protein Bet. This model represents the phage recombination protein Bet from a number of phage, including phage lambda. All members of this family are found in phage genomes or in putative prophage regions of bacterial genomes. [Mobile and extrachromosomal element functions, Prophage functions].	1.45393e-64
NC_018658.1\|WP_001067458.1\|3617181_3617412_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|374243	pfam15943, YdaS_antitoxin, Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT. YdaS_antitoxin is a family of putative bacterial antitoxins, neutralising the toxin YdaT, family pfam06254.	9.89251e-22
NC_018658.1\|WP_000995433.1\|3619086_3619383_+\|host-nuclease-inhibitor-protein-Gam	gnl\|CDD\|368728	pfam06064, Gam, Host-nuclease inhibitor protein Gam. The Gam protein inhibits RecBCD nuclease and is found in both bacteria and bacteriophage.	6.64909e-52
NC_018658.1\|WP_000186833.1\|3620170_3620851_+\|YqaJ-viral-recombinase-family-protein	gnl\|CDD\|378216	pfam09588, YqaJ, YqaJ-like viral recombinase domain. This protein family is found in many different bacterial species but is of viral origin. The protein forms an oligomer and functions as a processive alkaline exonuclease that digests linear double-stranded DNA in a Mg(2+)-dependent reaction, It has a preference for 5'-phosphorylated DNA ends. It thus forms part of the two-component SynExo viral recombinase functional unit.	2.29334e-29
NC_018658.1\|WP_001182903.1\|3616572_3617112_-\|toxin-YdaT-domain-containing-protein	gnl\|CDD\|368819	pfam06254, YdaT_toxin, Putative bacterial toxin ydaT. YdaT_toxin is a family of putative bacterial toxins that are neutralized by the putative antitoxin YdaS, UniProtKB:P76063, family pfam144549.	8.69182e-38
NC_018658.1\|WP_000224912.1\|3611520_3611691_-\|hypothetical-protein	gnl\|CDD\|182029	PRK09689, PRK09689, prophage protein NinE; Provisional.	2.24504e-26
NC_018658.1\|WP_000338663.1\|3613168_3613408_-\|hypothetical-protein	gnl\|CDD\|371129	pfam10548, P22_AR_C, P22AR C-terminal domain. This domain was identified by Iyer and colleagues. It is found associated with pfam10547.	1.44528e-11
NC_018658.1\|WP_000858975.1\|3617517_3618207_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	1.28713e-28

>NC_018658.1|WP_000788812.1|3614858_3615560_-|hypothetical-protein
MKNIAAQMVNFDCEQMRRIANNMPEQYDEKPQVQQVAQIINGVFSQLLATFPASLANRDQNELNEIRRQWVLAFRENGITTMEQVNAGMRVARRQNRPFLPSPGQFVAWCREEASVNAGLPNVSELVDMVYEYCRKRGLYPDAESYPWKSNAHYWLVTNLYQNMRANALTDAELRRKAADELTCMTARINRGETIPEPVKQLPVMGGRPLNRAQALAKIAEIKAKFGLKGARV
>NC_018658.1|WP_000145901.1|3614559_3614862_-|protein-ren
MTGKEAIIHYLGTHKKFCAQDVAAVTGATVTSINQAAAKMARAGILVVDGKVWRTVYYRFATREEWEGKVSTNLIFKECRQSAAMKRVLRVYKRTSMGTQ
>NC_018658.1|WP_000338663.1|3613168_3613408_-|hypothetical-protein
MDAGVLVLAVQQYPITKQFTDNKLCARAWLWRAGDVMLTACQNVTPLLQVAEHREAGRFTSIEHEYPQILNRARAILAR
>NC_018658.1|WP_001391403.1|3612340_3612592_-|hypothetical-protein
MEIIKQDSQQKEGNQALMLKQYFVNLLIMELYEEVHNGDAADSVFKSTEPTQVLDNLWSKWQEAIAFFDIWNYPVATEEDLAD
>NC_018658.1|WP_072147432.1|3612142_3612244_-|hypothetical-protein
MRTYKPTYLLHSQMQKCTCDILYPAFDLCGGEA
>NC_018658.1|WP_001053034.1|3611690_3612146_-|DNA-base-flipping-protein-YbcN
MNLPQDGIKLHRGNFTAIGRQIQPYLEEGKCFRMVLKPWREKRSLSQNALSHMWYSEISEYLISRGKTFATPAWVKDALKHTYLGYETKDLVDVVTGDITTIQSLRHTSDLDTGEMYVFLCKVEAWAVNIGCHLTIPQSCEFQLLRDKQEA
>NC_018658.1|WP_000224912.1|3611520_3611691_-|hypothetical-protein
MATPLIRVMNGHIYRVPDRRKRKPELKPSEIPTLLGYTASLVDKKWLRLAARRNHG
>NC_018658.1|WP_000774504.1|3611237_3611528_-|DUF1364-domain-containing-protein
MADLRKAARSRECQVRIPGVCNGNPETSVLAHIRLTGLCGTGTKPPDLIATIACSACHDEIDRRTHFVDAAYAKECALEGMARTQVIWLKEGVIKA
>NC_018658.1|WP_000971074.1|3610742_3610883_-|YlcG-family-protein
MMFEFYMAERLRHRWGRLRLYRFPGSVLTDYRILKNYAKTLTGAGV
>NC_018658.1|WP_001204791.1|3610273_3610657_-|antitermination-protein-QuuD
MRDIQMVLERWGAWAANNHEDVTWSSIAAGFKGLITSKVKSRPQCCDDDAMIICGCMARLKKNNSDLHDLLVDYYVVGMTFMSLAGKHCCSDGYIGKRLQKAEGIIEGMLMALDIRLEMDIVVNNSN
>NC_018658.1|WP_001182903.1|3616572_3617112_-|toxin-YdaT-domain-containing-protein
MQPLTYQQTSGFSPTAVINRSQTKQVPGHEKIRDAVRAWSAVDNQDVVATLIVNEYREQGGGTIDFPDDVSRARQKLFRFLDNKFDSEKYRNNVRELTPAILAVLPLEYRGYLVEQDSFMARLAEMEKELSEAKQAVILNAPRHQKLKEISEGIVSMFRVDPDLAGPLMAMVTTMLGAI
>NC_018658.1|WP_001067458.1|3617181_3617412_-|helix-turn-helix-domain-containing-protein
MNPAIKTAINIVGSQKKLGAACEVSQQAVYKWLHNKAKVSPEHVGSIVTATGGVVKAYQIRPDLPKLFPHTEKNAA
>NC_018658.1|WP_000858975.1|3617517_3618207_+|helix-turn-helix-transcriptional-regulator
MKTTLSERLKEARLARGLTQKALGDLVGVSQAAIQKIETGKANQTTKIVEIANALGVRAEWLSSGVGNMSDSTVQPIQSTVSHSKYFKIDVLDIEVSAGPGVINREFVEVLRSVEYSFDDARHMFDGRKAENIRIINVRGDSMSGTIEPGDLLFVDITVKSFDGDGIYAFLYDDTAHVKRLQMMKDKLLVISDNKSYSPWDPIEKDEMNRVFIFGKVIGSMPQTYRKHG
>NC_018658.1|WP_000233576.1|3618804_3619011_+|phage-encoded-cell-division-inhibitor-protein
MVHQHYGTQTVNRGAVMPGMLVKHKDGTWTASANLRGRLYLHRGIERTYTRDLLVEVFLDGRGNGLNH
>NC_018658.1|WP_000995433.1|3619086_3619383_+|host-nuclease-inhibitor-protein-Gam
MNAYYIQDRLEAQSWARHYQQIAREEKEAELADDMEKGLPQHLFESLCIDHLQRHGASKKAITRAFDDDVEFQERMAEHIQYMVETIAHHQVDIDSEV
>NC_018658.1|WP_000100847.1|3619388_3620174_+|phage-recombination-protein-Bet
MSTALATLAGKLAERVGMDSVDPQELITTLRQTAFKGDASDAQFIALLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVDGWSRIINENQQFDGMDFEQDNESCTCRIYRKDRNHPICVTEWMDECRREPFKTREGREITGPWQSHPKRMLRHKAMIQCARLAFGFAGIYDKDEAERIVENTAYTAERQPERDITPVNDETMQEINTLLIALDKTWDDDLLPLCSQIFRRDIRASSELTQAEAVKALGFLKQKATEQKVAA
>NC_018658.1|WP_000186833.1|3620170_3620851_+|YqaJ-viral-recombinase-family-protein
MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVTESPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMWVTRKDAWYFANYDPRMKREGLHYVVIERNEKYMANFDEMVPEFIEKMDVALAEIGFVFGEQWR
>NC_018658.1|WP_000682318.1|3620847_3621030_+|DUF1317-domain-containing-protein
MKHPHDNIRVGTITFVYSVTKRGWVFPGLSVIRNPLKAQRLAEEINNKRGAVCTKHLPLS
>NC_018658.1|WP_000548541.1|3621002_3621194_+|DUF1382-family-protein
MHKASPVELRTSIEMAHSLAQNGVRFVPIPVETDEEFHTLAASLSQKLEMMVAKAEADERDQV
>NC_018658.1|WP_000188870.1|3621270_3621486_+|hypothetical-protein
MTPQQENALRSIARQANSEIKKARQQFPDKNVDDICRSVLKKHRETVTLMGFTPTHLSLAIGMLNGVFKER

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Crispr_ID: NC_018658_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018658_7

3625819-3625963

Orphan

Consensus_repeat	Method
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_018658_7

>merge|NC_018658|7|3625819-3625963|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGCTGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTCGTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

>NC_018658|7|5|3625819-3625963|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	TGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTC
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018658.1\|WP_000120064.1\|3622016_3622619_-\|hypothetical-protein	unknown	unknown	unknown
NC_018658.1\|WP_001036475.1\|3628430_3629864_-\|anion-permease	unknown	unknown	gnl\|CDD\|279307
NC_018658.1\|WP_000186833.1\|3620170_3620851_+\|YqaJ-viral-recombinase-family-protein	unknown	unknown	gnl\|CDD\|378216
NC_018658.1\|WP_000593936.1\|3625986_3628248_-\|hydratase	unknown	unknown	gnl\|CDD\|183125
NC_018658.1\|WP_000548541.1\|3621002_3621194_+\|DUF1382-family-protein	unknown	unknown	gnl\|CDD\|369224
NC_018658.1\|WP_001303849.1\|3623068_3623287_+\|excisionase	unknown	unknown	gnl\|CDD\|116439
NC_018658.1\|WP_001091569.1\|3624469_3625753_+\|putative-acyl-CoA-thioester-hydrolase	unknown	unknown	gnl\|CDD\|236709
NC_018658.1\|WP_000763367.1\|3621584_3621806_+\|TraR/DksA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|222775
NC_018658.1\|WP_000891515.1\|3636828_3636978_-\|multidrug-efflux-pump-accessory-protein-AcrZ	unknown	unknown	gnl\|CDD\|371231
NC_018658.1\|WP_000682318.1\|3620847_3621030_+\|DUF1317-domain-containing-protein	unknown	unknown	gnl\|CDD\|284449
NC_018658.1\|WP_000891676.1\|3634138_3635197_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	unknown	unknown	gnl\|CDD\|182993
NC_018658.1\|WP_000723652.1\|3629939_3630992_-\|4-oxalomesaconate-tautomerase	unknown	unknown	gnl\|CDD\|380230
NC_018658.1\|WP_000101987.1\|3635888_3636662_-\|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|182641
NC_018658.1\|WP_000604032.1\|3635199_3635889_-\|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|181841
NC_018658.1\|WP_000188870.1\|3621270_3621486_+\|hypothetical-protein	unknown	unknown	unknown
NC_018658.1\|WP_000815435.1\|3632169_3633165_-\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|182912
NC_018658.1\|WP_000545745.1\|3622861_3623029_+\|hypothetical-protein	unknown	unknown	unknown
NC_018658.1\|WP_000679972.1\|3631175_3632129_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176131
NC_018658.1\|WP_000533642.1\|3623264_3624335_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271181
NC_018658.1\|WP_000213425.1\|3633319_3634138_+\|bifunctional-pyridoxal-phosphate/fructose-1,6-bisphosphate-phosphatase	unknown	unknown	gnl\|CDD\|182523

Protein	Function_ID	Function_description	E-value
NC_018658.1\|WP_000548541.1\|3621002_3621194_+\|DUF1382-family-protein	gnl\|CDD\|369224	pfam07131, DUF1382, Protein of unknown function (DUF1382). This family consists of several hypothetical Escherichia coli and bacteriophage lambda-like proteins of around 60 residues in length. The function of this family is unknown. Structural modelling suggests this domain may bind nucleic acids.	2.3749e-22
NC_018658.1\|WP_001036475.1\|3628430_3629864_-\|anion-permease	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	0
NC_018658.1\|WP_000186833.1\|3620170_3620851_+\|YqaJ-viral-recombinase-family-protein	gnl\|CDD\|378216	pfam09588, YqaJ, YqaJ-like viral recombinase domain. This protein family is found in many different bacterial species but is of viral origin. The protein forms an oligomer and functions as a processive alkaline exonuclease that digests linear double-stranded DNA in a Mg(2+)-dependent reaction, It has a preference for 5'-phosphorylated DNA ends. It thus forms part of the two-component SynExo viral recombinase functional unit.	2.29334e-29
NC_018658.1\|WP_000593936.1\|3625986_3628248_-\|hydratase	gnl\|CDD\|183125	PRK11413, PRK11413, putative hydratase; Provisional.	0
NC_018658.1\|WP_001303849.1\|3623068_3623287_+\|excisionase	gnl\|CDD\|116439	pfam07825, Exc, Excisionase-like protein. The phage-encoded excisionase protein (Xis) is involved in excisive recombination by regulating the assembly of the excisive intasome and by inhibiting viral integration. It adopts an unusual 'winged'-helix structure in which two alpha helices are packed against two extended strands. Also present in the structure is a two-stranded anti-parallel beta-sheet, whose strands are connected by a four-residue 'wing'. During interaction with DNA, helix alpha2 is thought to insert into the major groove, while the wing contacts the adjacent minor groove or phosphodiester backbone. The C-terminal region of Xis is involved in interaction with phage-encoded integrase (Int), and a putative C-terminal alpha helix may fold upon interaction with Int and/or DNA.	8.49552e-35
NC_018658.1\|WP_001091569.1\|3624469_3625753_+\|putative-acyl-CoA-thioester-hydrolase	gnl\|CDD\|236709	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase.	0
NC_018658.1\|WP_000763367.1\|3621584_3621806_+\|TraR/DksA-family-transcriptional-regulator	gnl\|CDD\|222775	PHA00080, PHA00080, DksA-like zinc finger domain containing protein.	1.57279e-26
NC_018658.1\|WP_000891515.1\|3636828_3636978_-\|multidrug-efflux-pump-accessory-protein-AcrZ	gnl\|CDD\|371231	pfam10766, AcrZ, Multidrug efflux pump-associated protein AcrZ. AcrZ is associated with the AcrA-TolC multidrug efflux pump, it may enhance the ability of the pump to recognize and export certain substrates.	1.04381e-17
NC_018658.1\|WP_000682318.1\|3620847_3621030_+\|DUF1317-domain-containing-protein	gnl\|CDD\|284449	pfam07026, DUF1317, Protein of unknown function (DUF1317). This family consists of several hypothetical bacterial and phage proteins of around 60 residues in length. The function of this family is unknown.	4.99888e-34
NC_018658.1\|WP_000891676.1\|3634138_3635197_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	gnl\|CDD\|182993	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC.	0
NC_018658.1\|WP_000723652.1\|3629939_3630992_-\|4-oxalomesaconate-tautomerase	gnl\|CDD\|380230	NF033377, OMA_tautomer, 4-oxalomesaconate tautomerase.	0
NC_018658.1\|WP_000101987.1\|3635888_3636662_-\|molybdate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|182641	PRK10677, modA, molybdate transporter periplasmic protein; Provisional.	0
NC_018658.1\|WP_000604032.1\|3635199_3635889_-\|molybdate-ABC-transporter-permease-subunit	gnl\|CDD\|181841	PRK09421, modB, molybdate ABC transporter permease subunit.	9.04539e-146
NC_018658.1\|WP_000815435.1\|3632169_3633165_-\|6-phosphogluconolactonase	gnl\|CDD\|182912	PRK11028, PRK11028, 6-phosphogluconolactonase; Provisional.	0
NC_018658.1\|WP_000679972.1\|3631175_3632129_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.09679e-82
NC_018658.1\|WP_000533642.1\|3623264_3624335_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271181	cd00800, INT_Lambda_C, C-terminal catalytic domain of Lambda integrase, a tyrosine-based site-specific recombinase. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome. They are tyrosine-based site-specific recombinase and belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The phage lambda integrase can bridge two different and well-separated DNA sequences called arm- and core-sites. The C-terminal domain binds, cleaves and re-ligates DNA strands at the core-sites, while the N-terminal domain is largely responsible for high-affinity binding to the arm-type sites.	1.09199e-61
NC_018658.1\|WP_000213425.1\|3633319_3634138_+\|bifunctional-pyridoxal-phosphate/fructose-1,6-bisphosphate-phosphatase	gnl\|CDD\|182523	PRK10530, PRK10530, pyridoxal phosphate (PLP) phosphatase; Provisional.	0

>NC_018658.1|WP_001091569.1|3624469_3625753_+|putative-acyl-CoA-thioester-hydrolase
MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPADWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFNAFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVDDNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK
>NC_018658.1|WP_000533642.1|3623264_3624335_+|tyrosine-type-recombinase/integrase
MGRRRSHERRDLPPNLYIRNNGYYCYRDPRTGKEFGLGRDRRIAITEAIQANIELFSGHKHKPLTARINSDNSVTLHSWLDRYEKILASRGIKQKTLINYMSKIKAIRRGLPDAPLEDITTKEIAAMLNGYIDEGKAASAKLIRSTLSDAFREAIAEGHITTNPVAATRAAKSEVRRSRLTADEYLKIYQAAESSPCWLRLAMELAVVTGQRVGDLCEMKWSDIVDGYLYVEQSKTGVKIAIPTALHVDALGISMKETLDKCKEILGGETIIASTRREPLSSGTVSRYFMRARKASGLSFEGDPPTFHELRSLSARLYEKQISDKFAQHLLGHKSDTMASQYRDDRGREWDKIEIK
>NC_018658.1|WP_001303849.1|3623068_3623287_+|excisionase
MYLTLQEWNARQRRPRSLETVRRWVRECRIFPPPVKDGREYLFHESAVKVDLNRPVTGSLLKRIRNGKKAKS
>NC_018658.1|WP_000545745.1|3622861_3623029_+|hypothetical-protein
MHFRVTGEWNGEPFNRVIEAENISDCYDHWMLWAQIAHADVTNIRIEELKEHQAA
>NC_018658.1|WP_000120064.1|3622016_3622619_-|hypothetical-protein
MSYFLRKKWMVNLSGSGKILWALNMKKDSYPYLICMTVSGLIFIFLFFWWRADIYRVTFLNQSISHYYILFSMGIAFLLSLFWVKKGIVKQRGWKSLSAYLKVYAGMCIFAGFFLIIPLTTLTYFLPGETSSYVAPYRYTSGSSKSCSGAEVDDPELHENIRICYPYGNYEYDNIIYVEKKINILGAVVTYAQTARDDTE
>NC_018658.1|WP_000763367.1|3621584_3621806_+|TraR/DksA-family-transcriptional-regulator
MADIIDSASEIEELQRNTAIKMRRLNHQAISATHCCECGDPIDERRRLVVQGCRTCASCQEDLELISKQRGSK
>NC_018658.1|WP_000188870.1|3621270_3621486_+|hypothetical-protein
MTPQQENALRSIARQANSEIKKARQQFPDKNVDDICRSVLKKHRETVTLMGFTPTHLSLAIGMLNGVFKER
>NC_018658.1|WP_000548541.1|3621002_3621194_+|DUF1382-family-protein
MHKASPVELRTSIEMAHSLAQNGVRFVPIPVETDEEFHTLAASLSQKLEMMVAKAEADERDQV
>NC_018658.1|WP_000682318.1|3620847_3621030_+|DUF1317-domain-containing-protein
MKHPHDNIRVGTITFVYSVTKRGWVFPGLSVIRNPLKAQRLAEEINNKRGAVCTKHLPLS
>NC_018658.1|WP_000186833.1|3620170_3620851_+|YqaJ-viral-recombinase-family-protein
MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVTESPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMWVTRKDAWYFANYDPRMKREGLHYVVIERNEKYMANFDEMVPEFIEKMDVALAEIGFVFGEQWR
>NC_018658.1|WP_000593936.1|3625986_3628248_-|hydratase
MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTMAVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVSALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPSSQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRSNPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIKAGSLINFNKNRQM
>NC_018658.1|WP_001036475.1|3628430_3629864_-|anion-permease
MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIVGLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAAFVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSVAVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISWGGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLGVFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGIIGLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAMLPVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGAVLTILTFLVHITLGVWWWNMLIGWNML
>NC_018658.1|WP_000723652.1|3629939_3630992_-|4-oxalomesaconate-tautomerase
MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGNDLEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGAFAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVALTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELDADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRALAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRASVIRTTRKIFSGEVYLP
>NC_018658.1|WP_000679972.1|3631175_3632129_+|LysR-family-transcriptional-regulator
MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFTPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDWFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG
>NC_018658.1|WP_000815435.1|3632169_3633165_-|6-phosphogluconolactonase
MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH
>NC_018658.1|WP_000213425.1|3633319_3634138_+|bifunctional-pyridoxal-phosphate/fructose-1,6-bisphosphate-phosphatase
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVNKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI
>NC_018658.1|WP_000891676.1|3634138_3635197_-|molybdenum-ABC-transporter-ATP-binding-protein-ModC
MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAISGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMAKSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLDIPRKRELLPYLQCLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWGSSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELVIKPGLWLYAQIKSVSITA
>NC_018658.1|WP_000604032.1|3635199_3635889_-|molybdate-ABC-transporter-permease-subunit
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITIPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
>NC_018658.1|WP_000101987.1|3635888_3636662_-|molybdate-ABC-transporter-substrate-binding-protein
MARKWLNLFAGAALSFAVAGNALADEGKITVFAAASLTNAMQDIATQYKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTASRQTLLGNSLVVVAPKASEQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKLGAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVATFPEDSHKKVEYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTTK
>NC_018658.1|WP_000891515.1|3636828_3636978_-|multidrug-efflux-pump-accessory-protein-AcrZ
MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQPGQNH

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_018658_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018658_8

3865115-3865211

Orphan

Consensus_repeat	Method
TTGTAGGCCTGATAAGATGCGTCAAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_018658_8

>merge|NC_018658|8|3865115-3865211|CRISPRCasFinder
TTGTAGGCCTGATAAGATGCGTCAAGCATCGCATCAGGCATTGTGCACCAATTGCCGGATGCGGCACCGGTTGTAGGCCTGATAAGACGCGTCAAGC

>NC_018658|8|6|3865115-3865211|CRISPRCasFinder
TTGTAGGCCTGATAAGATGCGTCAAGC	ATCGCATCAGGCATTGTGCACCAATTGCCGGATGCGGCACCGG
TTGTAGGCCTGATAAGACGCGTCAAGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018658.1\|WP_000776555.1\|3857812_3858355_-\|type-1-fimbrial-major-subunit-FimA	unknown	unknown	gnl\|CDD\|237920
NC_018658.1\|WP_001298987.1\|3874611_3875913_-\|uracil/xanthine-transporter	unknown	unknown	gnl\|CDD\|183124
NC_018658.1\|WP_000255997.1\|3862139_3862634_+\|peptidylprolyl-isomerase-B	unknown	unknown	gnl\|CDD\|182734
NC_018658.1\|WP_001306951.1\|3871284_3872520_+\|allantoate-deiminase	unknown	unknown	gnl\|CDD\|274471
NC_018658.1\|WP_000190288.1\|3859703_3859916_+\|ribosome-associated-protein-YbcJ	unknown	unknown	gnl\|CDD\|183166
NC_018658.1\|WP_000006887.1\|3875969_3877331_-\|allantoinase-AllB	unknown	unknown	gnl\|CDD\|169193
NC_018658.1\|WP_000855388.1\|3865244_3866138_-\|carbamate-kinase	unknown	unknown	gnl\|CDD\|181831
NC_018658.1\|WP_000729154.1\|3858835_3859702_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	unknown	unknown	gnl\|CDD\|236760
NC_018658.1\|WP_000706355.1\|3873444_3874590_-\|glycerate-3-kinase	unknown	unknown	gnl\|CDD\|182152
NC_018658.1\|WP_001143543.1\|3860023_3860545_+\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|224899
NC_018658.1\|WP_001295318.1\|3863476_3863986_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl\|CDD\|223119
NC_018658.1\|WP_000580806.1\|3868229_3869897_-\|acyl-CoA-synthetase-FdrA	unknown	unknown	gnl\|CDD\|180395
NC_018658.1\|WP_000495400.1\|3866960_3868220_-\|DUF1116-domain-containing-protein	unknown	unknown	gnl\|CDD\|377673
NC_018658.1\|WP_000703879.1\|3870213_3871263_+\|ureidoglycolate-dehydrogenase	unknown	unknown	gnl\|CDD\|184985
NC_018658.1\|WP_000912345.1\|3860580_3861966_-\|cysteine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234705
NC_018658.1\|WP_000988366.1\|3856900_3857593_-\|type-1-fimbria-chaperone-FimC	unknown	unknown	gnl\|CDD\|185117
NC_018658.1\|WP_000212252.1\|3862636_3863359_+\|UDP-2,3-diacylglucosamine-diphosphatase	unknown	unknown	gnl\|CDD\|235420
NC_018658.1\|WP_001306952.1\|3866134_3866950_-\|DUF2877-domain-containing-protein	unknown	unknown	gnl\|CDD\|378658
NC_018658.1\|WP_000540946.1\|3872530_3873316_+\|(S)-ureidoglycine-aminohydrolase	unknown	unknown	gnl\|CDD\|225796
NC_018658.1\|WP_000815551.1\|3863982_3865050_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674

Protein	Function_ID	Function_description	E-value
NC_018658.1\|WP_000776555.1\|3857812_3858355_-\|type-1-fimbrial-major-subunit-FimA	gnl\|CDD\|237920	PRK15194, PRK15194, type 1 fimbrial protein subunit FimA.	9.67411e-92
NC_018658.1\|WP_001298987.1\|3874611_3875913_-\|uracil/xanthine-transporter	gnl\|CDD\|183124	PRK11412, PRK11412, uracil/xanthine transporter.	0
NC_018658.1\|WP_000255997.1\|3862139_3862634_+\|peptidylprolyl-isomerase-B	gnl\|CDD\|182734	PRK10791, PRK10791, peptidylprolyl isomerase B.	9.12357e-121
NC_018658.1\|WP_001306951.1\|3871284_3872520_+\|allantoate-deiminase	gnl\|CDD\|274471	TIGR03176, AllC, allantoate amidohydrolase. This enzyme catalyzes the breakdown of allantoate, first to ureidoglycine by hydrolysis and then decarboxylation of one of the two equivalent ureido groups. Ureidoglycine then spontaneously exchanges ammonia for water resulting in ureidoglycolate. This enzyme is an alternative to allantoicase (3.5.3.4) which releases urea. [Central intermediary metabolism, Nitrogen metabolism].	0
NC_018658.1\|WP_000190288.1\|3859703_3859916_+\|ribosome-associated-protein-YbcJ	gnl\|CDD\|183166	PRK11507, PRK11507, ribosome-associated protein YbcJ.	1.38756e-42
NC_018658.1\|WP_000006887.1\|3875969_3877331_-\|allantoinase-AllB	gnl\|CDD\|169193	PRK08044, PRK08044, allantoinase AllB.	0
NC_018658.1\|WP_000855388.1\|3865244_3866138_-\|carbamate-kinase	gnl\|CDD\|181831	PRK09411, PRK09411, carbamate kinase; Reviewed.	0
NC_018658.1\|WP_000729154.1\|3858835_3859702_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	gnl\|CDD\|236760	PRK10792, PRK10792, bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD.	0
NC_018658.1\|WP_000706355.1\|3873444_3874590_-\|glycerate-3-kinase	gnl\|CDD\|182152	PRK09932, PRK09932, glycerate 3-kinase.	0
NC_018658.1\|WP_001143543.1\|3860023_3860545_+\|metal-dependent-hydrolase	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	7.12373e-31
NC_018658.1\|WP_001295318.1\|3863476_3863986_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl\|CDD\|223119	COG0041, PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism].	1.14024e-91
NC_018658.1\|WP_000580806.1\|3868229_3869897_-\|acyl-CoA-synthetase-FdrA	gnl\|CDD\|180395	PRK06091, PRK06091, membrane protein FdrA; Validated.	0
NC_018658.1\|WP_000495400.1\|3866960_3868220_-\|DUF1116-domain-containing-protein	gnl\|CDD\|377673	pfam06545, DUF1116, Protein of unknown function (DUF1116). This family contains hypothetical bacterial proteins of unknown function.	1.67788e-130
NC_018658.1\|WP_000703879.1\|3870213_3871263_+\|ureidoglycolate-dehydrogenase	gnl\|CDD\|184985	PRK15025, PRK15025, ureidoglycolate dehydrogenase; Provisional.	0
NC_018658.1\|WP_000912345.1\|3860580_3861966_-\|cysteine--tRNA-ligase	gnl\|CDD\|234705	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated.	0
NC_018658.1\|WP_000988366.1\|3856900_3857593_-\|type-1-fimbria-chaperone-FimC	gnl\|CDD\|185117	PRK15195, PRK15195, molecular chaperone FimC.	5.84958e-149
NC_018658.1\|WP_000212252.1\|3862636_3863359_+\|UDP-2,3-diacylglucosamine-diphosphatase	gnl\|CDD\|235420	PRK05340, PRK05340, UDP-2,3-diacylglucosamine hydrolase; Provisional.	1.37025e-165
NC_018658.1\|WP_001306952.1\|3866134_3866950_-\|DUF2877-domain-containing-protein	gnl\|CDD\|378658	pfam11392, DUF2877, Protein of unknown function (DUF2877). This bacterial family of proteins are putative carboxylase proteins however this cannot be confirmed.	2.28312e-37
NC_018658.1\|WP_000540946.1\|3872530_3873316_+\|(S)-ureidoglycine-aminohydrolase	gnl\|CDD\|225796	COG3257, GlxB, Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only].	4.36926e-152
NC_018658.1\|WP_000815551.1\|3863982_3865050_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	1.30115e-179

>NC_018658.1|WP_000815551.1|3863982_3865050_+|5-(carboxyamino)imidazole-ribonucleotide-synthase
MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQSVITAEIERWPETALTRELARHPAFVNRDVFPIIADRLTQKQLFDKLHLPTAPWQLLADRSEWPAVFERLGELAIVKRRTGGYDGRGQWRLRANETEQLPAECYGECIVEQGINFSGEVSLVGARGFDGSTVFYPLTHNLHQDGILRTSVAFPQANAQQQAQAEEMLSAIMQELGYVGVMAMECFVTPQGLLINELAPRVHNSGHWTQNGASISQFELHLRAITDLPLPQPVVNSPSVMINLIGSDVNYDWLKLPLVHLHWYDKEVRPGRKVGHLNLTDSDTSRLTATLEALIPLLPPEYASGVIWAQSKFG
>NC_018658.1|WP_001295318.1|3863476_3863986_+|5-(carboxyamino)imidazole-ribonucleotide-mutase
MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSAHRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVDSLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTDEVLENPDPRGAA
>NC_018658.1|WP_000212252.1|3862636_3863359_+|UDP-2,3-diacylglucosamine-diphosphatase
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
>NC_018658.1|WP_000255997.1|3862139_3862634_+|peptidylprolyl-isomerase-B
MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRVINGFMIQGGGFEPGMKQKATKEPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINVVDNDFLNFSGESLQGWGYCVFAEVVDGMDVVDKIKGVATGRSGMHQDVPKEDVIIESVTVSE
>NC_018658.1|WP_000912345.1|3860580_3861966_-|cysteine--tRNA-ligase
MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRRK
>NC_018658.1|WP_001143543.1|3860023_3860545_+|metal-dependent-hydrolase
MPTVITHAAVPLCIGLGLGSKVIPPRLLFAGIILAMLPDADVLSFKFGVAYGNVFGHRGFTHSLVFAFVVPLLCVLIGRRWFRAGLICCWLFLTVSLLSHSLLDSVTTGGKGVGWLWPWSDERFFAPWQVIKVAPFALSRYTTPYGHQVIISELMWVWLPGMVLMGMLWWRRR
>NC_018658.1|WP_000190288.1|3859703_3859916_+|ribosome-associated-protein-YbcJ
MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGQVKVDGAVETRKRCKIVAGQTVSFAGHSVQVVA
>NC_018658.1|WP_000729154.1|3858835_3859702_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD
MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQDE
>NC_018658.1|WP_000776555.1|3857812_3858355_-|type-1-fimbrial-major-subunit-FimA
MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVNTDSADQVVTLGQYRTDIFNAVGNTSALIPFTIQLNDCDPVVAANAAVAFSGQADAINDNLLAIASSTNTTTATGVGIEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGTGTSASAGQANADATFIMRYE
>NC_018658.1|WP_000988366.1|3856900_3857593_-|type-1-fimbria-chaperone-FimC
MMTKIKLLMLIIFYLIISASAHAAGGIALGATRIIYPADAKQTAVWIRNSHTNERFLVNSWIENSSGVKEKSFIITPPLFVSEPKSENTLRIIYTGPPLAADRESLFWMNVKTIPSVDKNALNGRNVLQLAILSRMKLFLRPIQLQELPAEAPDTLKFSRSGNYINVHNPSPFYVTLVNLQVGSQKLGNAMAAPRVSSQIPLPSGVQGKLKFQTVNDYGSVTPVREVNLN
>NC_018658.1|WP_000855388.1|3865244_3866138_-|carbamate-kinase
MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYRLAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVTTVLTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQPRKILDSEAIELLLKEGHVVICSGGGGVPVTEDGAGSEAVIDKDLAAALLAEQINADGLVILTDADAVYENWGTPQQRAIRHATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAWIGALSRIEETLAGEAGTCISL
>NC_018658.1|WP_001306952.1|3866134_3866950_-|DUF2877-domain-containing-protein
MTIIHPLLASRSAPNYRQSWRLAGVWRRAINLMTESGELLTLHRQGSGFGPGGWMLRRAQFDALCGGLCGNERPQVVAQGIRLGRFTVKQPQRYCLLRITPPAHPQPLAAAWMQRAEETGLFGPLALAASDPLPAELRQFRHCFQAALNGVKTDWRHWLGKGPGLTPSHDDTLSGMLLAAWYYGALDARSGRQFFACSDNLQLVTTAVSVSYLRYAAQGYFASPLLHFVHALSCPKRTAVAIDSLLALGHTSGADTLLGFWLGQQLLQGKP
>NC_018658.1|WP_000495400.1|3866960_3868220_-|DUF1116-domain-containing-protein
MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNPGKTLLHAGPPMRWQEMTGPMKGACVGACLFEGWAKDEAQALAILEQGEVNFIPCHHVNAVGPMGGITSASMPMLVVENVTDGNRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLSAALGRMEHGIDLTAMMAQGITMGDEFHQRNIASSALLMRALAPQIARLDHDKQHIAEVMDFLSVTDQFFLNLAMAYCKAAMDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFTAPVNTPQGLFFTGFSQEQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGAGGMEAARAVSEEMAEIYLERNMQLQIPGWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQIGAGTVRAPLACFEQALEALAESMGIG
>NC_018658.1|WP_000580806.1|3868229_3869897_-|acyl-CoA-synthetase-FdrA
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTDFWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSLALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHHHGMMLDADGHQIIDLGDDFYTVGRPHPMIDPALRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARSDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIRPLSPATQQHTPSLMENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ
>NC_018658.1|WP_000703879.1|3870213_3871263_+|ureidoglycolate-dehydrogenase
MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAEQNGVAVVGISRMGHSGAISYFVQQAARAGLIGISMCQSDPMVVPFGGAEIYYGTNPLAFAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGAPTTDPLAVHALLPAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSSELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISDALYNTSYETKNPFAQ
>NC_018658.1|WP_001306951.1|3871284_3872520_+|allantoate-deiminase
MITHFRQAIEETLPWLSSFGADPTGGMTRLLYSPEWLETQQQFKKRMAASGLETRFDEVGNLYGRLNGTEYPQEVILSGSHIDTVVNGGNLDGQFGALAAWLAIDWLKTQYGAPLRTVEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNSFVDAMKACGFTLPNAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTVTLNGESNHAGTTPMGYRRDTVYAFSRICHQSVEKAKRMGDPLVLTFGKVEPRPNTVNVVPGKTTFTIDCRHTDAAVLRDFTQQLENDMRAICDEMDIGIDIDLWMDEEPVPMNKELVATLTELCESEKLNYRVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITDLAEGVKTLALMLYQLAWQK
>NC_018658.1|WP_000540946.1|3872530_3873316_+|(S)-ureidoglycine-aminohydrolase
MGYLNNVTGYRDDLLANRAIVKHGNFALLTPDGLVKNIIPGFENCDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFALSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYVPVEGHAPWLVSGNASELERIHYEGMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNNWIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI
>NC_018658.1|WP_000706355.1|3873444_3874590_-|glycerate-3-kinase
MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDANYICLPIADGGEGTVDAMVAATGGNIVTLEVCGPMGEKVNAFYGLTGDGKTAVIEMAAASGLMLVAPEKRNPLLASSFGTGELIRHALDNGIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQVLVANGGNLARVASIEMDECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEMVEELEQGLQNYARVLQQQTEINVCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAVNLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVHQYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN
>NC_018658.1|WP_001298987.1|3874611_3875913_-|uracil/xanthine-transporter
MFNFAVSRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLLTLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWGTILTITLGEASRGTPINDIATSLAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFGIADPNFKIQLPPFALSVAVMCLVLGMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSHSLSGELHWQWFPLGSGGALSPGIILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTRYRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYTRRSFIYGSVICLLVALVPALTRLFCSIPLPVSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMALPPVYLQDLPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE
>NC_018658.1|WP_000006887.1|3875969_3877331_-|allantoinase-AllB
MSFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVMDASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFKGAQKLGELGQPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHVCHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMEAWGGIAGLQNCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTNDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_018658_5	5.1\|3255589\|40\|NC_018658\|CRISPRCasFinder	3255589-3255628	40	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	47951-47990	0	1.0
NC_018658_6	6.2\|3616093\|25\|NC_018658\|PILER-CR	3616093-3616117	25	NC_049946	Escherichia virus Lambda_4A7 genome assembly, chromosome: 1	37604-37628	0	1.0
NC_018658_6	6.2\|3616093\|25\|NC_018658\|PILER-CR	3616093-3616117	25	LR595861	Escherichia virus Lambda_4C10 genome assembly, chromosome: 1	37887-37911	0	1.0
NC_018658_6	6.1\|3616046\|24\|NC_018658\|PILER-CR	3616046-3616069	24	NC_049946	Escherichia virus Lambda_4A7 genome assembly, chromosome: 1	37652-37675	1	0.958
NC_018658_6	6.1\|3616046\|24\|NC_018658\|PILER-CR	3616046-3616069	24	LR595861	Escherichia virus Lambda_4C10 genome assembly, chromosome: 1	37935-37958	1	0.958
NC_018658_6	6.2\|3616093\|25\|NC_018658\|PILER-CR	3616093-3616117	25	NZ_AP023208	Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence	44524-44548	1	0.96
NC_018658_4	4.1\|2442669\|38\|NC_018658\|CRISPRCasFinder	2442669-2442706	38	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	113727-113764	2	0.947
NC_018658_6	6.1\|3616046\|24\|NC_018658\|PILER-CR	3616046-3616069	24	NZ_AP023208	Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence	44572-44595	2	0.917
NC_018658_6	6.2\|3616093\|25\|NC_018658\|PILER-CR	3616093-3616117	25	NZ_CP015341	Lactobacillus brevis strain 100D8 plasmid unnamed3, complete sequence	35661-35685	4	0.84
NC_018658_2	2.2\|1161100\|33\|NC_018658\|PILER-CR	1161100-1161132	33	NZ_CP038598	Salmonella enterica subsp. enterica serovar Hadar strain 12-2388 plasmid p12-2388.3, complete sequence	2051-2083	7	0.788
NC_018658_2	2.2\|1161100\|33\|NC_018658\|PILER-CR	1161100-1161132	33	NZ_CP033827	Klebsiella sp. FDAARGOS_511 plasmid unnamed4, complete sequence	692-724	7	0.788
NC_018658_2	2.2\|1161100\|33\|NC_018658\|PILER-CR	1161100-1161132	33	NZ_CP029125	Enterobacter hormaechei strain AR432 plasmid unnamed2, complete sequence	518-550	7	0.788
NC_018658_2	2.2\|1161100\|33\|NC_018658\|PILER-CR	1161100-1161132	33	NZ_AP019693	Salmonella enterica subsp. enterica serovar Senftenberg strain SL180013 plasmid pSL180013-1, complete sequence	2811-2843	7	0.788
NC_018658_2	2.2\|1161100\|33\|NC_018658\|PILER-CR	1161100-1161132	33	NZ_CP030192	Salmonella enterica strain SA20104250 plasmid pSA20104250.2, complete sequence	1835-1867	7	0.788
NC_018658_2	2.2\|1161100\|33\|NC_018658\|PILER-CR	1161100-1161132	33	NZ_CP039274	Salmonella enterica subsp. enterica serovar Senftenberg str. CFSAN004025 plasmid pCFSAN004025.4, complete sequence	118-150	7	0.788
NC_018658_2	2.2\|1161100\|33\|NC_018658\|PILER-CR	1161100-1161132	33	NZ_CP016528	Salmonella enterica subsp. enterica serovar Heidelberg strain 09-036813-1A plasmid p09-036813-1A_4, complete sequence	52-84	7	0.788
NC_018658_2	2.2\|1161100\|33\|NC_018658\|PILER-CR	1161100-1161132	33	NZ_CP030227	Salmonella enterica strain SA20041605 plasmid pSA20041605.2, complete sequence	3123-3155	7	0.788
NC_018658_2	2.2\|1161100\|33\|NC_018658\|PILER-CR	1161100-1161132	33	NC_013090	Endophytic bacterium LOB-07 plasmid pLK39, complete sequence	52-84	7	0.788
NC_018658_2	2.2\|1161100\|33\|NC_018658\|PILER-CR	1161100-1161132	33	NZ_CP030009	Enterobacter hormaechei subsp. xiangfangensis strain Pb204 plasmid pPb204002, complete sequence	2572-2604	7	0.788
NC_018658_2	2.2\|1161100\|33\|NC_018658\|PILER-CR	1161100-1161132	33	NZ_CP011606	Citrobacter freundii strain CAV1321 plasmid pCAV1321-4310, complete sequence	3835-3867	7	0.788
NC_018658_2	2.2\|1161100\|33\|NC_018658\|PILER-CR	1161100-1161132	33	NZ_CP044113	Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed4, complete sequence	3638-3670	7	0.788
NC_018658_2	2.15\|1161101\|32\|NC_018658\|CRISPRCasFinder,CRT	1161101-1161132	32	NZ_CP038598	Salmonella enterica subsp. enterica serovar Hadar strain 12-2388 plasmid p12-2388.3, complete sequence	2052-2083	7	0.781
NC_018658_2	2.15\|1161101\|32\|NC_018658\|CRISPRCasFinder,CRT	1161101-1161132	32	NZ_CP033827	Klebsiella sp. FDAARGOS_511 plasmid unnamed4, complete sequence	693-724	7	0.781
NC_018658_2	2.15\|1161101\|32\|NC_018658\|CRISPRCasFinder,CRT	1161101-1161132	32	NZ_CP029125	Enterobacter hormaechei strain AR432 plasmid unnamed2, complete sequence	518-549	7	0.781
NC_018658_2	2.15\|1161101\|32\|NC_018658\|CRISPRCasFinder,CRT	1161101-1161132	32	NZ_AP019693	Salmonella enterica subsp. enterica serovar Senftenberg strain SL180013 plasmid pSL180013-1, complete sequence	2812-2843	7	0.781
NC_018658_2	2.15\|1161101\|32\|NC_018658\|CRISPRCasFinder,CRT	1161101-1161132	32	NZ_CP030192	Salmonella enterica strain SA20104250 plasmid pSA20104250.2, complete sequence	1835-1866	7	0.781
NC_018658_2	2.15\|1161101\|32\|NC_018658\|CRISPRCasFinder,CRT	1161101-1161132	32	NZ_CP039274	Salmonella enterica subsp. enterica serovar Senftenberg str. CFSAN004025 plasmid pCFSAN004025.4, complete sequence	118-149	7	0.781
NC_018658_2	2.15\|1161101\|32\|NC_018658\|CRISPRCasFinder,CRT	1161101-1161132	32	NZ_CP016528	Salmonella enterica subsp. enterica serovar Heidelberg strain 09-036813-1A plasmid p09-036813-1A_4, complete sequence	53-84	7	0.781
NC_018658_2	2.15\|1161101\|32\|NC_018658\|CRISPRCasFinder,CRT	1161101-1161132	32	NZ_CP030227	Salmonella enterica strain SA20041605 plasmid pSA20041605.2, complete sequence	3124-3155	7	0.781
NC_018658_2	2.15\|1161101\|32\|NC_018658\|CRISPRCasFinder,CRT	1161101-1161132	32	NC_013090	Endophytic bacterium LOB-07 plasmid pLK39, complete sequence	53-84	7	0.781
NC_018658_2	2.15\|1161101\|32\|NC_018658\|CRISPRCasFinder,CRT	1161101-1161132	32	NZ_CP030009	Enterobacter hormaechei subsp. xiangfangensis strain Pb204 plasmid pPb204002, complete sequence	2572-2603	7	0.781
NC_018658_2	2.15\|1161101\|32\|NC_018658\|CRISPRCasFinder,CRT	1161101-1161132	32	NZ_CP011606	Citrobacter freundii strain CAV1321 plasmid pCAV1321-4310, complete sequence	3835-3866	7	0.781
NC_018658_2	2.15\|1161101\|32\|NC_018658\|CRISPRCasFinder,CRT	1161101-1161132	32	NZ_CP044113	Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed4, complete sequence	3639-3670	7	0.781
NC_018658_2	2.19\|1161345\|32\|NC_018658\|CRISPRCasFinder,CRT	1161345-1161376	32	MN693005	Marine virus AFVG_117M50, complete genome	6262-6293	7	0.781
NC_018658_2	2.1\|1161039\|33\|NC_018658\|PILER-CR	1161039-1161071	33	NZ_CP012265	Cronobacter condimenti 1330 strain LMG 26250 plasmid pCCO1, complete sequence	26062-26094	8	0.758
NC_018658_2	2.6\|1161344\|33\|NC_018658\|PILER-CR	1161344-1161376	33	MN693005	Marine virus AFVG_117M50, complete genome	6262-6294	8	0.758
NC_018658_2	2.11\|1161649\|33\|NC_018658\|PILER-CR	1161649-1161681	33	MK016501	Mycobacterium phage Nebkiss, complete genome	21453-21485	8	0.758
NC_018658_2	2.11\|1161649\|33\|NC_018658\|PILER-CR	1161649-1161681	33	NC_026590	Mycobacterium phage Gaia, complete genome	21452-21484	8	0.758
NC_018658_2	2.14\|1161040\|32\|NC_018658\|CRISPRCasFinder,CRT	1161040-1161071	32	NZ_CP012265	Cronobacter condimenti 1330 strain LMG 26250 plasmid pCCO1, complete sequence	26063-26094	8	0.75
NC_018658_2	2.15\|1161101\|32\|NC_018658\|CRISPRCasFinder,CRT	1161101-1161132	32	NC_019341	Pseudomonas syringae plasmid pNCPPB880-40, complete sequence	6612-6643	8	0.75
NC_018658_2	2.17\|1161223\|32\|NC_018658\|CRISPRCasFinder,CRT	1161223-1161254	32	AB452989	Serratia phage KSP20 orf7 to orf11 genes for scaffolding protein, major capsid protein, terminase, head completion protein, hypothetical protein, complete and partial cds	1966-1997	8	0.75
NC_018658_2	2.19\|1161345\|32\|NC_018658\|CRISPRCasFinder,CRT	1161345-1161376	32	MK295204	Shigella phage vB_SdyM_006, complete genome	16122-16153	8	0.75
NC_018658_2	2.19\|1161345\|32\|NC_018658\|CRISPRCasFinder,CRT	1161345-1161376	32	MG696114	Proteus phage phiP4-3, complete genome	149804-149835	8	0.75
NC_018658_2	2.19\|1161345\|32\|NC_018658\|CRISPRCasFinder,CRT	1161345-1161376	32	NZ_CP017949	Tenericutes bacterium MO-XQ plasmid unnamed, complete sequence	58006-58037	8	0.75
NC_018658_2	2.22\|1161528\|32\|NC_018658\|CRISPRCasFinder,CRT	1161528-1161559	32	NZ_CP010769	Phaeobacter piscinae strain P13 plasmid pP13_b, complete sequence	121002-121033	8	0.75
NC_018658_2	2.24\|1161650\|32\|NC_018658\|CRISPRCasFinder,CRT	1161650-1161681	32	MK016501	Mycobacterium phage Nebkiss, complete genome	21454-21485	8	0.75
NC_018658_2	2.24\|1161650\|32\|NC_018658\|CRISPRCasFinder,CRT	1161650-1161681	32	NC_026590	Mycobacterium phage Gaia, complete genome	21453-21484	8	0.75
NC_018658_2	2.6\|1161344\|33\|NC_018658\|PILER-CR	1161344-1161376	33	MK295204	Shigella phage vB_SdyM_006, complete genome	16121-16153	9	0.727
NC_018658_2	2.6\|1161344\|33\|NC_018658\|PILER-CR	1161344-1161376	33	MG696114	Proteus phage phiP4-3, complete genome	149804-149836	9	0.727
NC_018658_2	2.14\|1161040\|32\|NC_018658\|CRISPRCasFinder,CRT	1161040-1161071	32	NC_006569	Ruegeria pomeroyi DSS-3 megaplasmid, complete sequence	460266-460297	9	0.719
NC_018658_2	2.19\|1161345\|32\|NC_018658\|CRISPRCasFinder,CRT	1161345-1161376	32	AP022649	Bacillus wiedmannii PL1 plasmid pBwiPL1-6 DNA, complete sequence	5394-5425	9	0.719
NC_018658_2	2.19\|1161345\|32\|NC_018658\|CRISPRCasFinder,CRT	1161345-1161376	32	KC821606	Cellulophaga phage phi12:2, complete genome	1257-1288	9	0.719
NC_018658_2	2.19\|1161345\|32\|NC_018658\|CRISPRCasFinder,CRT	1161345-1161376	32	KT070867	Bacillus phage PBC2, complete genome	154855-154886	9	0.719
NC_018658_2	2.6\|1161344\|33\|NC_018658\|PILER-CR	1161344-1161376	33	AP022649	Bacillus wiedmannii PL1 plasmid pBwiPL1-6 DNA, complete sequence	5394-5426	10	0.697
NC_018658_2	2.14\|1161040\|32\|NC_018658\|CRISPRCasFinder,CRT	1161040-1161071	32	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1538980-1539011	10	0.688
NC_018658_2	2.14\|1161040\|32\|NC_018658\|CRISPRCasFinder,CRT	1161040-1161071	32	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1187025-1187056	10	0.688
NC_018658_2	2.14\|1161040\|32\|NC_018658\|CRISPRCasFinder,CRT	1161040-1161071	32	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1615960-1615991	10	0.688
NC_018658_2	2.14\|1161040\|32\|NC_018658\|CRISPRCasFinder,CRT	1161040-1161071	32	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	1459996-1460027	10	0.688
NC_018658_2	2.14\|1161040\|32\|NC_018658\|CRISPRCasFinder,CRT	1161040-1161071	32	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	1531874-1531905	10	0.688
NC_018658_2	2.14\|1161040\|32\|NC_018658\|CRISPRCasFinder,CRT	1161040-1161071	32	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	1459018-1459049	10	0.688
NC_018658_2	2.14\|1161040\|32\|NC_018658\|CRISPRCasFinder,CRT	1161040-1161071	32	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1526371-1526402	10	0.688
NC_018658_2	2.14\|1161040\|32\|NC_018658\|CRISPRCasFinder,CRT	1161040-1161071	32	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1526372-1526403	10	0.688
NC_018658_2	2.14\|1161040\|32\|NC_018658\|CRISPRCasFinder,CRT	1161040-1161071	32	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	1459988-1460019	10	0.688
NC_018658_2	2.14\|1161040\|32\|NC_018658\|CRISPRCasFinder,CRT	1161040-1161071	32	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	1459341-1459372	10	0.688
NC_018658_2	2.14\|1161040\|32\|NC_018658\|CRISPRCasFinder,CRT	1161040-1161071	32	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	1459978-1460009	10	0.688
NC_018658_2	2.14\|1161040\|32\|NC_018658\|CRISPRCasFinder,CRT	1161040-1161071	32	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1539145-1539176	10	0.688
NC_018658_2	2.14\|1161040\|32\|NC_018658\|CRISPRCasFinder,CRT	1161040-1161071	32	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1539126-1539157	10	0.688
NC_018658_2	2.14\|1161040\|32\|NC_018658\|CRISPRCasFinder,CRT	1161040-1161071	32	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1539107-1539138	10	0.688
NC_018658_2	2.19\|1161345\|32\|NC_018658\|CRISPRCasFinder,CRT	1161345-1161376	32	KC821631	Cellulophaga phage phi48:1, complete genome	1257-1288	10	0.688
NC_018658_2	2.19\|1161345\|32\|NC_018658\|CRISPRCasFinder,CRT	1161345-1161376	32	KC821628	Cellulophaga phage phi18:4, complete genome	1257-1288	10	0.688
NC_018658_2	2.19\|1161345\|32\|NC_018658\|CRISPRCasFinder,CRT	1161345-1161376	32	NC_021805	Cellulophaga phage phi12a:1, complete genome	1257-1288	10	0.688
NC_018658_2	2.23\|1161589\|32\|NC_018658\|CRISPRCasFinder,CRT	1161589-1161620	32	KU160664	Arthrobacter phage Salgado, complete genome	140-171	11	0.656
NC_018658_2	2.23\|1161589\|32\|NC_018658\|CRISPRCasFinder,CRT	1161589-1161620	32	MF140418	Arthrobacter phage LiSara, complete genome	140-171	11	0.656
NC_018658_2	2.23\|1161589\|32\|NC_018658\|CRISPRCasFinder,CRT	1161589-1161620	32	KU160654	Arthrobacter phage Laroye, complete genome	140-171	11	0.656

1. spacer 5.1|3255589|40|NC_018658|CRISPRCasFinder matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 0, identity: 1.0

gcgctgcgggtcattcttgaaattacccccgctgtgctgt	CRISPR spacer
gcgctgcgggtcattcttgaaattacccccgctgtgctgt	Protospacer
****************************************

2. spacer 6.2|3616093|25|NC_018658|PILER-CR matches to NC_049946 (Escherichia virus Lambda_4A7 genome assembly, chromosome: 1) position: , mismatch: 0, identity: 1.0

tttacctctttcaggtaaactttat	CRISPR spacer
tttacctctttcaggtaaactttat	Protospacer
*************************

3. spacer 6.2|3616093|25|NC_018658|PILER-CR matches to LR595861 (Escherichia virus Lambda_4C10 genome assembly, chromosome: 1) position: , mismatch: 0, identity: 1.0

tttacctctttcaggtaaactttat	CRISPR spacer
tttacctctttcaggtaaactttat	Protospacer
*************************

4. spacer 6.1|3616046|24|NC_018658|PILER-CR matches to NC_049946 (Escherichia virus Lambda_4A7 genome assembly, chromosome: 1) position: , mismatch: 1, identity: 0.958

cgcctttacctgatgtgggtaaac	CRISPR spacer
cgcctttacctgatttgggtaaac	Protospacer
************** *********

5. spacer 6.1|3616046|24|NC_018658|PILER-CR matches to LR595861 (Escherichia virus Lambda_4C10 genome assembly, chromosome: 1) position: , mismatch: 1, identity: 0.958

cgcctttacctgatgtgggtaaac	CRISPR spacer
cgcctttacctgatttgggtaaac	Protospacer
************** *********

6. spacer 6.2|3616093|25|NC_018658|PILER-CR matches to NZ_AP023208 (Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence) position: , mismatch: 1, identity: 0.96

tttacctctttcaggtaaactttat	CRISPR spacer
tttacctctttaaggtaaactttat	Protospacer
*********** *************

7. spacer 4.1|2442669|38|NC_018658|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 2, identity: 0.947

cggacgcaggatggtgcgttcaattggactcgaaccaa	CRISPR spacer
cagacgcagaatggtgcgttcaattggactcgaaccaa	Protospacer
*.*******.****************************

8. spacer 6.1|3616046|24|NC_018658|PILER-CR matches to NZ_AP023208 (Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence) position: , mismatch: 2, identity: 0.917

cgcctttacctgatgtgggtaaac	CRISPR spacer
tgcctttacctgatttgggtaaac	Protospacer
.************* *********

9. spacer 6.2|3616093|25|NC_018658|PILER-CR matches to NZ_CP015341 (Lactobacillus brevis strain 100D8 plasmid unnamed3, complete sequence) position: , mismatch: 4, identity: 0.84

tttacctctttcaggtaaactttat	CRISPR spacer
ggtatctcattcaggtaaactttat	Protospacer
  **.*** ****************

10. spacer 2.2|1161100|33|NC_018658|PILER-CR matches to NZ_CP038598 (Salmonella enterica subsp. enterica serovar Hadar strain 12-2388 plasmid p12-2388.3, complete sequence) position: , mismatch: 7, identity: 0.788

gaaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
gaaaagggccgcattagcggccc----ttttcggaga	Protospacer
***************..******    ** ***

11. spacer 2.2|1161100|33|NC_018658|PILER-CR matches to NZ_CP033827 (Klebsiella sp. FDAARGOS_511 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.788

gaaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
gaaaagggccgcattagcggccc----ttttcggaga	Protospacer
***************..******    ** ***

12. spacer 2.2|1161100|33|NC_018658|PILER-CR matches to NZ_CP029125 (Enterobacter hormaechei strain AR432 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.788

gaaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
gaaaagggccgcattagcggccc----ttttcggaga	Protospacer
***************..******    ** ***

13. spacer 2.2|1161100|33|NC_018658|PILER-CR matches to NZ_AP019693 (Salmonella enterica subsp. enterica serovar Senftenberg strain SL180013 plasmid pSL180013-1, complete sequence) position: , mismatch: 7, identity: 0.788

gaaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
gaaaagggccgcattagcggccc----ttttcggaga	Protospacer
***************..******    ** ***

14. spacer 2.2|1161100|33|NC_018658|PILER-CR matches to NZ_CP030192 (Salmonella enterica strain SA20104250 plasmid pSA20104250.2, complete sequence) position: , mismatch: 7, identity: 0.788

gaaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
gaaaagggccgcattagcggccc----ttttcggaga	Protospacer
***************..******    ** ***

15. spacer 2.2|1161100|33|NC_018658|PILER-CR matches to NZ_CP039274 (Salmonella enterica subsp. enterica serovar Senftenberg str. CFSAN004025 plasmid pCFSAN004025.4, complete sequence) position: , mismatch: 7, identity: 0.788

gaaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
gaaaagggccgcattagcggccc----ttttcggaga	Protospacer
***************..******    ** ***

16. spacer 2.2|1161100|33|NC_018658|PILER-CR matches to NZ_CP016528 (Salmonella enterica subsp. enterica serovar Heidelberg strain 09-036813-1A plasmid p09-036813-1A_4, complete sequence) position: , mismatch: 7, identity: 0.788

gaaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
gaaaagggccgcattagcggccc----ttttcggaga	Protospacer
***************..******    ** ***

17. spacer 2.2|1161100|33|NC_018658|PILER-CR matches to NZ_CP030227 (Salmonella enterica strain SA20041605 plasmid pSA20041605.2, complete sequence) position: , mismatch: 7, identity: 0.788

gaaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
gaaaagggccgcattagcggccc----ttttcggaga	Protospacer
***************..******    ** ***

18. spacer 2.2|1161100|33|NC_018658|PILER-CR matches to NC_013090 (Endophytic bacterium LOB-07 plasmid pLK39, complete sequence) position: , mismatch: 7, identity: 0.788

gaaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
gaaaagggccgcattagcggccc----ttttcggaga	Protospacer
***************..******    ** ***

19. spacer 2.2|1161100|33|NC_018658|PILER-CR matches to NZ_CP030009 (Enterobacter hormaechei subsp. xiangfangensis strain Pb204 plasmid pPb204002, complete sequence) position: , mismatch: 7, identity: 0.788

gaaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
gaaaagggccgcattagcggccc----ttttcggaga	Protospacer
***************..******    ** ***

20. spacer 2.2|1161100|33|NC_018658|PILER-CR matches to NZ_CP011606 (Citrobacter freundii strain CAV1321 plasmid pCAV1321-4310, complete sequence) position: , mismatch: 7, identity: 0.788

gaaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
gaaaagggccgcattagcggccc----ttttcggaga	Protospacer
***************..******    ** ***

21. spacer 2.2|1161100|33|NC_018658|PILER-CR matches to NZ_CP044113 (Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.788

gaaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
gaaaagggccgcattagcggccc----ttttcggaga	Protospacer
***************..******    ** ***

22. spacer 2.15|1161101|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP038598 (Salmonella enterica subsp. enterica serovar Hadar strain 12-2388 plasmid p12-2388.3, complete sequence) position: , mismatch: 7, identity: 0.781

aaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
aaaagggccgcattagcggccc----ttttcggaga	Protospacer
**************..******    ** ***

23. spacer 2.15|1161101|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP033827 (Klebsiella sp. FDAARGOS_511 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.781

aaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
aaaagggccgcattagcggccc----ttttcggaga	Protospacer
**************..******    ** ***

24. spacer 2.15|1161101|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP029125 (Enterobacter hormaechei strain AR432 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

aaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
aaaagggccgcattagcggccc----ttttcggaga	Protospacer
**************..******    ** ***

25. spacer 2.15|1161101|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_AP019693 (Salmonella enterica subsp. enterica serovar Senftenberg strain SL180013 plasmid pSL180013-1, complete sequence) position: , mismatch: 7, identity: 0.781

aaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
aaaagggccgcattagcggccc----ttttcggaga	Protospacer
**************..******    ** ***

26. spacer 2.15|1161101|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP030192 (Salmonella enterica strain SA20104250 plasmid pSA20104250.2, complete sequence) position: , mismatch: 7, identity: 0.781

aaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
aaaagggccgcattagcggccc----ttttcggaga	Protospacer
**************..******    ** ***

27. spacer 2.15|1161101|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP039274 (Salmonella enterica subsp. enterica serovar Senftenberg str. CFSAN004025 plasmid pCFSAN004025.4, complete sequence) position: , mismatch: 7, identity: 0.781

aaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
aaaagggccgcattagcggccc----ttttcggaga	Protospacer
**************..******    ** ***

28. spacer 2.15|1161101|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP016528 (Salmonella enterica subsp. enterica serovar Heidelberg strain 09-036813-1A plasmid p09-036813-1A_4, complete sequence) position: , mismatch: 7, identity: 0.781

aaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
aaaagggccgcattagcggccc----ttttcggaga	Protospacer
**************..******    ** ***

29. spacer 2.15|1161101|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP030227 (Salmonella enterica strain SA20041605 plasmid pSA20041605.2, complete sequence) position: , mismatch: 7, identity: 0.781

aaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
aaaagggccgcattagcggccc----ttttcggaga	Protospacer
**************..******    ** ***

30. spacer 2.15|1161101|32|NC_018658|CRISPRCasFinder,CRT matches to NC_013090 (Endophytic bacterium LOB-07 plasmid pLK39, complete sequence) position: , mismatch: 7, identity: 0.781

aaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
aaaagggccgcattagcggccc----ttttcggaga	Protospacer
**************..******    ** ***

31. spacer 2.15|1161101|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP030009 (Enterobacter hormaechei subsp. xiangfangensis strain Pb204 plasmid pPb204002, complete sequence) position: , mismatch: 7, identity: 0.781

aaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
aaaagggccgcattagcggccc----ttttcggaga	Protospacer
**************..******    ** ***

32. spacer 2.15|1161101|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP011606 (Citrobacter freundii strain CAV1321 plasmid pCAV1321-4310, complete sequence) position: , mismatch: 7, identity: 0.781

aaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
aaaagggccgcattagcggccc----ttttcggaga	Protospacer
**************..******    ** ***

33. spacer 2.15|1161101|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP044113 (Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.781

aaaagggccgcattgacggccctgtgttatcg----	CRISPR spacer
aaaagggccgcattagcggccc----ttttcggaga	Protospacer
**************..******    ** ***

34. spacer 2.19|1161345|32|NC_018658|CRISPRCasFinder,CRT matches to MN693005 (Marine virus AFVG_117M50, complete genome) position: , mismatch: 7, identity: 0.781

atttttcagactcatcaaaataatcctttaat	CRISPR spacer
tttgttcatactcatcaaaataatctataact	Protospacer
 ** **** ****************. * * *

35. spacer 2.1|1161039|33|NC_018658|PILER-CR matches to NZ_CP012265 (Cronobacter condimenti 1330 strain LMG 26250 plasmid pCCO1, complete sequence) position: , mismatch: 8, identity: 0.758

aggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
aagaactggcgctgctggagaaaatccgcaaag	Protospacer
*.****************** *** **  . *

36. spacer 2.6|1161344|33|NC_018658|PILER-CR matches to MN693005 (Marine virus AFVG_117M50, complete genome) position: , mismatch: 8, identity: 0.758

gatttttcagactcatcaaaataatcctttaat	CRISPR spacer
ctttgttcatactcatcaaaataatctataact	Protospacer
  ** **** ****************. * * *

37. spacer 2.11|1161649|33|NC_018658|PILER-CR matches to MK016501 (Mycobacterium phage Nebkiss, complete genome) position: , mismatch: 8, identity: 0.758

gacacctctactgacgttcctgaacaagaagat	CRISPR spacer
gacacctccactggcgttcctgaacgtattcat	Protospacer
********.****.***********. .   **

38. spacer 2.11|1161649|33|NC_018658|PILER-CR matches to NC_026590 (Mycobacterium phage Gaia, complete genome) position: , mismatch: 8, identity: 0.758

gacacctctactgacgttcctgaacaagaagat	CRISPR spacer
gacacctccactggcgttcctgaacgtattcat	Protospacer
********.****.***********. .   **

39. spacer 2.14|1161040|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP012265 (Cronobacter condimenti 1330 strain LMG 26250 plasmid pCCO1, complete sequence) position: , mismatch: 8, identity: 0.75

ggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
agaactggcgctgctggagaaaatccgcaaag	Protospacer
.****************** *** **  . *

40. spacer 2.15|1161101|32|NC_018658|CRISPRCasFinder,CRT matches to NC_019341 (Pseudomonas syringae plasmid pNCPPB880-40, complete sequence) position: , mismatch: 8, identity: 0.75

aaaagggccgcattgacggccctgtgttatcg	CRISPR spacer
aaaagggccgcattagcggcccttttaatttg	Protospacer
**************..******* *    *.*

41. spacer 2.17|1161223|32|NC_018658|CRISPRCasFinder,CRT matches to AB452989 (Serratia phage KSP20 orf7 to orf11 genes for scaffolding protein, major capsid protein, terminase, head completion protein, hypothetical protein, complete and partial cds) position: , mismatch: 8, identity: 0.75

gggtggcggtggtgctgtaattcacaccggta	CRISPR spacer
ggcgcgtggtggtgctgttgttcacaccggcc	Protospacer
**   *.*********** .**********.

42. spacer 2.19|1161345|32|NC_018658|CRISPRCasFinder,CRT matches to MK295204 (Shigella phage vB_SdyM_006, complete genome) position: , mismatch: 8, identity: 0.75

atttttcagactcatcaaaataatcctttaat-----	CRISPR spacer
gtttttcataatcatcaaaataatc-----atgacca	Protospacer
.******* * **************     **

43. spacer 2.19|1161345|32|NC_018658|CRISPRCasFinder,CRT matches to MG696114 (Proteus phage phiP4-3, complete genome) position: , mismatch: 8, identity: 0.75

atttttcagactcatcaaaataatcctttaat-----	CRISPR spacer
gtttttcataatcatcaaaataatc-----atgacca	Protospacer
.******* * **************     **

44. spacer 2.19|1161345|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP017949 (Tenericutes bacterium MO-XQ plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

-----atttttcagactcatcaaaataatcctttaat	CRISPR spacer
cagtgatt-----aacccatctaaataatcctttaat	Protospacer
     ***     .**.**** ***************

45. spacer 2.22|1161528|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP010769 (Phaeobacter piscinae strain P13 plasmid pP13_b, complete sequence) position: , mismatch: 8, identity: 0.75

ccgtcaaacagtatcaccgcgttaacgcccgc	CRISPR spacer
cccacaaacagtagcatcgcgttaacgatcaa	Protospacer
**  ********* **.********** .*.

46. spacer 2.24|1161650|32|NC_018658|CRISPRCasFinder,CRT matches to MK016501 (Mycobacterium phage Nebkiss, complete genome) position: , mismatch: 8, identity: 0.75

acacctctactgacgttcctgaacaagaagat	CRISPR spacer
acacctccactggcgttcctgaacgtattcat	Protospacer
*******.****.***********. .   **

47. spacer 2.24|1161650|32|NC_018658|CRISPRCasFinder,CRT matches to NC_026590 (Mycobacterium phage Gaia, complete genome) position: , mismatch: 8, identity: 0.75

acacctctactgacgttcctgaacaagaagat	CRISPR spacer
acacctccactggcgttcctgaacgtattcat	Protospacer
*******.****.***********. .   **

48. spacer 2.6|1161344|33|NC_018658|PILER-CR matches to MK295204 (Shigella phage vB_SdyM_006, complete genome) position: , mismatch: 9, identity: 0.727

gatttttcagactcatcaaaataatcctttaat-----	CRISPR spacer
cgtttttcataatcatcaaaataatc-----atgacca	Protospacer
 .******* * **************     **

49. spacer 2.6|1161344|33|NC_018658|PILER-CR matches to MG696114 (Proteus phage phiP4-3, complete genome) position: , mismatch: 9, identity: 0.727

gatttttcagactcatcaaaataatcctttaat-----	CRISPR spacer
cgtttttcataatcatcaaaataatc-----atgacca	Protospacer
 .******* * **************     **

50. spacer 2.14|1161040|32|NC_018658|CRISPRCasFinder,CRT matches to NC_006569 (Ruegeria pomeroyi DSS-3 megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.719

ggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
ggccaaggcgctgctggaacagaacccggacc	Protospacer
**    ************.**.*******  .

51. spacer 2.19|1161345|32|NC_018658|CRISPRCasFinder,CRT matches to AP022649 (Bacillus wiedmannii PL1 plasmid pBwiPL1-6 DNA, complete sequence) position: , mismatch: 9, identity: 0.719

atttttcagactcatcaaaataatcctttaat	CRISPR spacer
ccctatcatattcatcaaaataatcctttgcg	Protospacer
 ..* *** *.******************.

52. spacer 2.19|1161345|32|NC_018658|CRISPRCasFinder,CRT matches to KC821606 (Cellulophaga phage phi12:2, complete genome) position: , mismatch: 9, identity: 0.719

atttttcagactcatcaaaataatcctttaat	CRISPR spacer
gttttttaaactcatcaaaataataacctacc	Protospacer
.*****.*.***************  ..** .

53. spacer 2.19|1161345|32|NC_018658|CRISPRCasFinder,CRT matches to KT070867 (Bacillus phage PBC2, complete genome) position: , mismatch: 9, identity: 0.719

atttttcagactcatcaaaataatcctttaat	CRISPR spacer
atttttcagacttatcaaaagaacagtcggaa	Protospacer
************.******* **.  *. .*

54. spacer 2.6|1161344|33|NC_018658|PILER-CR matches to AP022649 (Bacillus wiedmannii PL1 plasmid pBwiPL1-6 DNA, complete sequence) position: , mismatch: 10, identity: 0.697

gatttttcagactcatcaaaataatcctttaat	CRISPR spacer
tccctatcatattcatcaaaataatcctttgcg	Protospacer
  ..* *** *.******************.

55. spacer 2.14|1161040|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

ggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
tcaactggcgctgctggaggacaacgagcggc	Protospacer
  ***************** * ***  *  ..

56. spacer 2.14|1161040|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.688

ggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
cctgctggcggtgctggagcagaaccccgcgg	Protospacer
   .****** **********.***** *..

57. spacer 2.14|1161040|32|NC_018658|CRISPRCasFinder,CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 10, identity: 0.688

ggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
tcaactggcgctgctggaggacaacgagcggc	Protospacer
  ***************** * ***  *  ..

58. spacer 2.14|1161040|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

ggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
tcaactggcgctgctggaggacaacgagcggc	Protospacer
  ***************** * ***  *  ..

59. spacer 2.14|1161040|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

ggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
tcaactggcgctgctggaggacaacgagcggc	Protospacer
  ***************** * ***  *  ..

60. spacer 2.14|1161040|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 10, identity: 0.688

ggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
tcaactggcgctgctggaggacaacgagcggc	Protospacer
  ***************** * ***  *  ..

61. spacer 2.14|1161040|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

ggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
tcaactggcgctgctggaggacaacgagcggc	Protospacer
  ***************** * ***  *  ..

62. spacer 2.14|1161040|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

ggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
tcaactggcgctgctggaggacaacgagcggc	Protospacer
  ***************** * ***  *  ..

63. spacer 2.14|1161040|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

ggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
tcaactggcgctgctggaggacaacgagcggc	Protospacer
  ***************** * ***  *  ..

64. spacer 2.14|1161040|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

ggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
tcaactggcgctgctggaggacaacgagcggc	Protospacer
  ***************** * ***  *  ..

65. spacer 2.14|1161040|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

ggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
tcaactggcgctgctggaggacaacgagcggc	Protospacer
  ***************** * ***  *  ..

66. spacer 2.14|1161040|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

ggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
tcaactggcgctgctggaggacaacgagcggc	Protospacer
  ***************** * ***  *  ..

67. spacer 2.14|1161040|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

ggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
tcaactggcgctgctggaggacaacgagcggc	Protospacer
  ***************** * ***  *  ..

68. spacer 2.14|1161040|32|NC_018658|CRISPRCasFinder,CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

ggaactggcgctgctggagcaaaacccggtat	CRISPR spacer
tcaactggcgctgctggaggacaacgagcggc	Protospacer
  ***************** * ***  *  ..

69. spacer 2.19|1161345|32|NC_018658|CRISPRCasFinder,CRT matches to KC821631 (Cellulophaga phage phi48:1, complete genome) position: , mismatch: 10, identity: 0.688

atttttcagactcatcaaaataatcctttaat	CRISPR spacer
gttttttaaactcatcaaaataataacccacc	Protospacer
.*****.*.***************  ...* .

70. spacer 2.19|1161345|32|NC_018658|CRISPRCasFinder,CRT matches to KC821628 (Cellulophaga phage phi18:4, complete genome) position: , mismatch: 10, identity: 0.688

atttttcagactcatcaaaataatcctttaat	CRISPR spacer
gttttttaaactcatcaaaataataacccacc	Protospacer
.*****.*.***************  ...* .

71. spacer 2.19|1161345|32|NC_018658|CRISPRCasFinder,CRT matches to NC_021805 (Cellulophaga phage phi12a:1, complete genome) position: , mismatch: 10, identity: 0.688

atttttcagactcatcaaaataatcctttaat	CRISPR spacer
gttttttaaactcatcaaaataataacccacc	Protospacer
.*****.*.***************  ...* .

72. spacer 2.23|1161589|32|NC_018658|CRISPRCasFinder,CRT matches to KU160664 (Arthrobacter phage Salgado, complete genome) position: , mismatch: 11, identity: 0.656

ccacacacgtcgagctggtgggggttaatgct	CRISPR spacer
aacggggcgtcgggctggtgggggtgaatgta	Protospacer
    . .*****.************ ****.

73. spacer 2.23|1161589|32|NC_018658|CRISPRCasFinder,CRT matches to MF140418 (Arthrobacter phage LiSara, complete genome) position: , mismatch: 11, identity: 0.656

ccacacacgtcgagctggtgggggttaatgct	CRISPR spacer
aacggggcgtcgggctggtgggggtgaatgta	Protospacer
    . .*****.************ ****.

74. spacer 2.23|1161589|32|NC_018658|CRISPRCasFinder,CRT matches to KU160654 (Arthrobacter phage Laroye, complete genome) position: , mismatch: 11, identity: 0.656

ccacacacgtcgagctggtgggggttaatgct	CRISPR spacer
aacggggcgtcgggctggtgggggtgaatgta	Protospacer
    . .*****.************ ****.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

68778 : 91393

Escherichia_phage(33.33%)

transposase,integrase

attL 71348:71377|attR 91389:91418

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000844627.1\|68778_69021_-\|transposase	transposase	NA	NA	NA	NA
WP_001300563.1\|69892_71005_+\|transposase	IS4-like element IS421 family transposase	NA	NA	NA	NA
71348:71377	attL	NA	NA	NA	NA
WP_000429836.1\|71372_71807_-	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_001294663.1\|71878_72229_+	mercuric transport protein MerT	NA	NA	NA	NA
WP_000732292.1\|72242_72518_+	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_001340589.1\|72553_72976_+	organomercurial transporter MerC	NA	NA	NA	NA
WP_000105636.1\|73027_74722_+	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	8.8e-39	27.6
WP_001277456.1\|74739_75102_+	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_000993386.1\|75098_75335_+	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_001300294.1\|75370_76039_+	EAL domain-containing protein	NA	NA	NA	NA
WP_001067855.1\|77428_78133_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000480968.1\|78193_79030_-	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
WP_001082319.1\|79029_79833_-	aminoglycoside O-phosphotransferase APH(3'')-Ib	Q75ZG1	Hepacivirus	4.9e-24	34.3
WP_001043265.1\|79893_80709_-	sulfonamide-resistant dihydropteroate synthase Sul2	NA	NA	NA	NA
WP_000240536.1\|81016_81868_-	replication protein	NA	NA	NA	NA
WP_001067855.1\|82623_83328_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001067855.1\|83452_84157_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000259029.1\|84190_84970_-	dihydropteroate synthase	NA	NA	NA	NA
WP_000679427.1\|84963_85311_-	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000703418.1\|85540_86014_-	trimethoprim-resistant dihydrofolate reductase DfrA7	A0A1B2IBQ4	Erwinia_phage	8.4e-16	32.0
WP_000845048.1\|86171_87185_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_000454193.1\|87387_87738_+	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_000147567.1\|87863_88424_+	recombinase family protein	A0A1B0V7I5	Salmonella_phage	4.0e-49	86.2
WP_001138064.1\|88426_91393_+\|transposase	Tn3-like element TnAs3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.6
91389:91418	attR	NA	NA	NA	NA

DBSCAN-SWA_2

890683 : 923836

Escherichia_phage(40.0%)

transposase,protease,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001390300.1\|890683_892486_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_001173975.1\|892476_893409_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_000198270.1\|893421_895404_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	2.2e-12	35.6
WP_000005080.1\|895414_895882_+	hypothetical protein	NA	NA	NA	NA
WP_001390299.1\|895891_896191_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_001033155.1\|896194_897271_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_000152746.1\|897278_897830_+	type VI secretion lipoprotein TssJ	NA	NA	NA	NA
WP_001154665.1\|897848_899261_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_001028113.1\|899599_900190_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_000914956.1\|900195_903600_+	type VI secretion protein	NA	NA	NA	NA
WP_000029846.1\|903603_906153_+	type VI secretion system ATPase TssH	A0A1C3S747	Escherichia_phage	4.6e-92	33.8
WP_000587872.1\|911587_912154_+	hypothetical protein	NA	NA	NA	NA
WP_000359994.1\|912632_913787_+	type VI secretion system ImpA family N-terminal domain-containing protein	NA	NA	NA	NA
WP_077577697.1\|916273_916636_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	6.4e-40	62.5
WP_001390760.1\|917431_918556_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	3.3e-199	99.7
WP_001045650.1\|919717_923836_-\|protease	serine protease autotransporter toxin Pic	Q9LA54	Enterobacteria_phage	0.0e+00	45.8

DBSCAN-SWA_3

1205326 : 1212466

Escherichia_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001278994.1\|1205326_1205965_-	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	75.0
WP_000590392.1\|1205961_1207224_-	3-oxo-tetronate kinase	A0A077SLJ7	Escherichia_phage	1.3e-135	61.4
WP_000847985.1\|1207220_1208129_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	3.0e-118	76.9
WP_001297141.1\|1208324_1209092_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	3.3e-70	56.7
WP_001141316.1\|1209142_1209799_-	protein-serine/threonine phosphatase	A0A077SLQ6	Escherichia_phage	1.5e-50	46.8
WP_001272924.1\|1209904_1212466_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.7e-30	20.6

DBSCAN-SWA_4

1572517 : 1604475

Enterobacteria_phage(47.06%)

protease,terminase,portal,integrase,head

attL 1570049:1570065|attR 1607729:1607745

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1570049:1570065	attL	NA	NA	NA	NA
WP_000194515.1\|1572517_1573951_-	sucrose-6-phosphate hydrolase	F8WPR5	Bacillus_phage	7.0e-29	25.4
WP_001274887.1\|1574166_1575081_+	aminoimidazole riboside kinase	NA	NA	NA	NA
WP_001197025.1\|1575152_1576400_+	oligosaccharide MFS transporter	NA	NA	NA	NA
WP_001163428.1\|1576929_1577130_-	response regulator inhibitor TorI	K7P7V0	Enterobacteria_phage	2.4e-33	100.0
WP_001277767.1\|1577261_1577441_-	Eag protein	K7PL40	Enterobacteria_phage	2.5e-29	100.0
WP_000208008.1\|1577537_1578167_-	DUF550 domain-containing protein	K7P7E3	Enterobacteria_phage	1.1e-55	58.6
WP_000951713.1\|1578163_1578373_-	hypothetical protein	A0A0F6TJE4	Escherichia_coli_O157_typing_phage	1.3e-32	91.2
WP_000034245.1\|1578735_1579407_-	ead/Ea22-like family protein	A0A0F6R7P8	Escherichia_coli_O157_typing_phage	3.0e-83	73.2
WP_001214454.1\|1579403_1579571_-	DUF2737 family protein	Q716F2	Shigella_phage	8.6e-24	98.2
WP_032159494.1\|1579567_1579849_-	hypothetical protein	K7P7M4	Enterobacteria_phage	9.7e-44	98.9
WP_001111299.1\|1579868_1580165_-	DUF2856 family protein	A5VWB0	Enterobacteria_phage	3.9e-51	99.0
WP_000951329.1\|1580188_1580572_-	hypothetical protein	K7P7R8	Enterobacteria_phage	1.2e-65	97.6
WP_000031367.1\|1580571_1581177_-	ERF family protein	K7P6W7	Enterobacteria_phage	4.1e-108	100.0
WP_000050554.1\|1581187_1581358_-	hypothetical protein	K7PJW0	Enterobacteria_phage	3.0e-24	100.0
WP_001243355.1\|1581433_1581586_-	host cell division inhibitory peptide Kil	A5VWA5	Enterobacteria_phage	4.7e-21	100.0
WP_000638547.1\|1581570_1581702_-\|protease	protease FtsH-inhibitory lysogeny factor CIII	A5VWA4	Enterobacteria_phage	1.4e-16	100.0
WP_000807788.1\|1582748_1582991_+	DUF2560 family protein	A5VW77	Enterobacteria_phage	1.3e-36	100.0
WP_000113732.1\|1582993_1583434_+	hypothetical protein	C7U0V7	Enterobacteria_phage	1.7e-79	99.3
WP_000200769.1\|1583430_1584843_+\|terminase	PBSX family phage terminase large subunit	Q716H3	Shigella_phage	9.8e-278	99.8
WP_000852341.1\|1584845_1586972_+\|portal	portal protein	Q9AYZ9	Salmonella_phage	0.0e+00	99.0
WP_000426730.1\|1586985_1587870_+	hypothetical protein	Q716H1	Shigella_phage	2.0e-143	99.0
WP_001133485.1\|1587881_1589153_+\|head	head protein	Q9AYZ7	Salmonella_phage	1.2e-239	99.5
WP_000375637.1\|1589195_1589381_+	hypothetical protein	Q716G9	Shigella_phage	2.7e-26	100.0
WP_000246749.1\|1589355_1589838_+	packaged DNA stabilization protein p27	Q716G8	Shigella_phage	8.4e-88	99.4
WP_001122379.1\|1589846_1591265_+	packaged DNA stabilization protein gp10	Q9AYZ4	Salmonella_phage	3.9e-274	98.9
WP_000785547.1\|1591264_1592113_+	Packaged DNA stabilization protein gp26	Q716G6	Shigella_phage	3.4e-100	97.5
WP_000614045.1\|1592112_1592568_+	DUF2824 family protein	Q716G5	Shigella_phage	5.7e-86	98.7
WP_000964882.1\|1592570_1593263_+	DNA transfer protein	G5DA80	Enterobacteria_phage	9.2e-112	100.0
WP_000246924.1\|1593272_1594739_+	phage DNA ejection protein	B6SCW4	Bacteriophage	8.4e-139	62.0
WP_001387755.1\|1594738_1596583_+	DNA transfer protein	A0A192Y934	Salmonella_phage	4.0e-247	73.8
WP_000749286.1\|1596597_1597083_-	lipoprotein	NA	NA	NA	NA
WP_000820795.1\|1597108_1597423_-	hypothetical protein	NA	NA	NA	NA
WP_001283829.1\|1597419_1597671_-	Arc family DNA-binding protein	A5VW59	Enterobacteria_phage	1.5e-35	93.9
WP_000865490.1\|1597776_1597917_+	Arc family DNA-binding protein	A0A0M4S6R9	Salmonella_phage	7.5e-05	56.8
WP_000835342.1\|1598149_1599028_+	phage repressor protein/antirepressor Ant	I6R977	Salmonella_phage	5.8e-95	78.1
WP_000129924.1\|1599128_1601108_+\|head	phage head-binding domain-containing protein	A5VW57	Enterobacteria_phage	6.2e-60	93.5
WP_000178979.1\|1601178_1603089_-	acyltransferase	C6ZR20	Salmonella_phage	4.7e-57	32.6
WP_000958672.1\|1603317_1604475_-\|integrase	prophage integrase IntS	A5VW56	Enterobacteria_phage	5.3e-221	100.0
1607729:1607745	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1838277 : 1847719

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000569326.1\|1838277_1839204_+	glycine betaine ABC transporter ATP binding protein YehX	G3M9Y6	Bacillus_virus	2.8e-23	30.8
WP_000783120.1\|1839208_1839940_+	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_001216963.1\|1839920_1840028_-	protein YohO	NA	NA	NA	NA
WP_001240401.1\|1840087_1840819_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	9.7e-112	99.5
WP_001295431.1\|1841040_1842726_+	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
WP_000598641.1\|1842722_1843442_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001295430.1\|1843488_1843959_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
WP_001295429.1\|1843999_1844461_-	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	1.9e-76	100.0
WP_001351453.1\|1844585_1846586_-	SWIM zinc finger family protein	Q9EYF6	Enterobacteria_phage	0.0e+00	96.3
WP_001292767.1\|1846582_1847719_-	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	4.6e-161	97.1

DBSCAN-SWA_6

2138299 : 2236700

113

Enterobacteria_phage(35.71%)

tail,capsid,protease,tRNA,terminase,holin,portal,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001025327.1\|2138299_2140033_-\|tRNA	arginine--tRNA ligase	A0A2K9L6Z2	Tupanvirus	6.8e-87	33.7
WP_001326063.1\|2140248_2140815_+	VOC family protein	NA	NA	NA	NA
WP_001185740.1\|2140828_2141575_+	copper homeostasis protein CutC	NA	NA	NA	NA
WP_001214304.1\|2141962_2143063_+	NapC/NirT family cytochrome c	NA	NA	NA	NA
WP_000176815.1\|2143087_2145517_+	trimethylamine N-oxide reductase TorZ	NA	NA	NA	NA
WP_000564745.1\|2145682_2146654_-\|tRNA	tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB	NA	NA	NA	NA
WP_000019588.1\|2146650_2147394_-	carboxy-S-adenosyl-L-methionine synthase CmoA	F5B419	Synechococcus_phage	4.6e-24	30.0
WP_000252979.1\|2147434_2147830_-	MAPEG family protein	NA	NA	NA	NA
WP_044713004.1\|2147882_2148653_-	DUF72 domain-containing protein	Q859D1	Escherichia_coli_phage	6.1e-72	99.2
WP_000362003.1\|2148634_2149945_-	DUF3596 domain-containing protein	Q8W658	Enterobacteria_phage	3.0e-244	95.4
WP_000528718.1\|2150000_2150237_-	excisionase family protein	Q8W657	Enterobacteria_phage	6.4e-41	100.0
WP_001030156.1\|2150245_2150392_-	hypothetical protein	A0A1B5FPC2	Escherichia_phage	1.6e-21	93.8
WP_000457723.1\|2150395_2150638_-	DUF4222 domain-containing protein	Q6H9Z8	Enterobacteria_phage	4.3e-32	87.5
WP_000628772.1\|2150722_2151481_-	phage protein	A0A1U9AJ59	Stx1_converting_phage	2.7e-109	82.0
WP_000065512.1\|2151994_2152543_-	ead/Ea22-like family protein	A0A1I9LJM5	Stx_converting_phage	1.4e-59	97.5
WP_000476208.1\|2152539_2152779_-	hypothetical protein	S5MQM0	Escherichia_phage	1.6e-34	94.9
WP_000111289.1\|2152771_2152975_-	hypothetical protein	K7PLX1	Enterobacteria_phage	1.0e-31	98.5
WP_001242713.1\|2152971_2153334_-	phage protein	K7PH61	Enterobacteria_phage	6.8e-66	97.5
WP_000008178.1\|2153324_2153861_-	5'-deoxynucleotidase	A0A0P0ZCH9	Stx2-converting_phage	2.2e-100	99.4
WP_000081306.1\|2153988_2154813_-	DUF2303 family protein	K7PJQ6	Enterobacteria_phage	1.1e-148	98.9
WP_000179185.1\|2154878_2155241_-	hypothetical protein	Q8SBF8	Shigella_phage	7.5e-57	94.2
WP_001387485.1\|2155943_2156636_-	helix-turn-helix domain-containing protein	S5FUZ3	Shigella_phage	6.4e-121	96.1
WP_001191669.1\|2156733_2156994_+	helix-turn-helix transcriptional regulator	K7PJQ8	Enterobacteria_phage	5.4e-41	100.0
WP_000526669.1\|2156986_2157544_+	hypothetical protein	Q8SBF4	Shigella_phage	5.3e-94	94.1
WP_001087340.1\|2157540_2158686_+	Rha family transcriptional regulator	A5LH69	Enterobacteria_phage	3.1e-173	83.5
WP_000620687.1\|2158682_2158907_+	hypothetical protein	A5LH70	Enterobacteria_phage	2.4e-37	95.9
WP_000061508.1\|2158903_2159722_+	helix-turn-helix domain-containing protein	A5LH71	Enterobacteria_phage	2.8e-123	88.1
WP_001387484.1\|2159718_2160213_+	PerC family transcriptional regulator	A0A291AWV6	Escherichia_phage	1.5e-84	96.3
WP_000066917.1\|2160212_2160866_+	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	1.9e-127	99.5
WP_000210143.1\|2160862_2161189_+	LexA family transcriptional regulator	A0A291AWY9	Escherichia_phage	2.7e-53	98.1
WP_000767110.1\|2161185_2161581_+	RusA family crossover junction endodeoxyribonuclease	A0A0P0ZD39	Stx2-converting_phage	5.7e-66	98.4
WP_001072672.1\|2161743_2162559_+	KilA-N domain-containing protein	U5P4K5	Shigella_phage	2.2e-149	99.6
WP_001390267.1\|2162566_2163556_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	1.4e-193	99.4
WP_001205460.1\|2163573_2163915_+	antitermination protein	A0A0P0ZCW0	Stx2-converting_phage	4.2e-57	90.3
WP_001131905.1\|2163927_2164476_-	hypothetical protein	NA	NA	NA	NA
WP_000868396.1\|2164462_2165389_-	hypothetical protein	NA	NA	NA	NA
WP_000917724.1\|2165653_2165857_+	hypothetical protein	A0A291AWX6	Escherichia_phage	6.1e-32	100.0
WP_000935520.1\|2166008_2167058_+	site-specific DNA-methyltransferase	S5MDR0	Escherichia_phage	3.1e-188	91.4
WP_000874354.1\|2167849_2169703_+	SASA family carbohydrate esterase	H6WZJ9	Escherichia_phage	0.0e+00	90.6
WP_000284510.1\|2169853_2170069_+\|holin	class II holin family protein	G9L6J5	Escherichia_phage	9.0e-34	100.0
WP_000731196.1\|2170073_2170880_+	YdfR family protein	Q08JA0	Stx2-converting_phage	4.8e-152	99.6
WP_000551290.1\|2170889_2171204_-	hypothetical protein	Q08J99	Stx2-converting_phage	4.7e-55	100.0
WP_001092910.1\|2171332_2171866_+	lysozyme	Q08J98	Stx2-converting_phage	1.1e-101	96.6
WP_001151822.1\|2172022_2172205_+	hypothetical protein	NA	NA	NA	NA
WP_001280932.1\|2172219_2172351_+	hypothetical protein	A0A0P0ZG36	Escherichia_phage	2.6e-07	79.1
WP_071587457.1\|2172573_2172759_+	hypothetical protein	A0A0P0ZE50	Stx2-converting_phage	9.9e-21	80.3
WP_000347013.1\|2173171_2173312_+	hypothetical protein	NA	NA	NA	NA
WP_001329960.1\|2173444_2173630_-	DUF3950 domain-containing protein	A0A0K2FIR8	Escherichia_phage	3.2e-19	90.4
WP_000867568.1\|2174024_2174573_+\|terminase	terminase small subunit	A0A0U2S671	Escherichia_phage	1.0e-57	84.2
WP_001390579.1\|2174544_2176473_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	7.4e-260	66.6
WP_000259002.1\|2176456_2176663_+\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	7.9e-11	56.9
WP_000831738.1\|2176659_2178252_+\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	4.2e-184	60.5
WP_001253924.1\|2178241_2179747_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	3.0e-99	52.8
WP_000256823.1\|2179783_2180131_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	8.9e-23	58.1
WP_000522601.1\|2180188_2181217_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.1e-113	62.2
WP_000201501.1\|2181268_2181652_+	DNA-packaging protein FI	NA	NA	NA	NA
WP_001204556.1\|2181644_2181998_+\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	1.1e-41	70.1
WP_000975010.1\|2182012_2182588_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	6.4e-50	57.8
WP_000683079.1\|2182584_2182980_+\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	1.5e-58	82.4
WP_000235110.1\|2182987_2183740_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	1.2e-133	98.4
WP_000479035.1\|2183753_2184176_+\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	1.1e-70	97.1
WP_000533444.1\|2184202_2184616_+\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	2.1e-42	82.2
WP_000081813.1\|2184596_2187209_+\|tail	phage tail tape measure protein	Q687F3	Enterobacteria_phage	0.0e+00	87.1
WP_000847379.1\|2187205_2187535_+\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	9.6e-59	100.0
WP_001152522.1\|2187534_2188233_+\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	3.4e-130	97.4
WP_000140762.1\|2188237_2188981_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	6.1e-146	94.7
WP_000090891.1\|2188917_2189550_+\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	2.2e-96	99.5
WP_000515718.1\|2189610_2193006_+	host specificity protein J	A0A0K2FI38	Escherichia_phage	0.0e+00	88.6
WP_001228314.1\|2193073_2193673_+	Ail/Lom family protein	Q9EV15	Enterobacteria_phage	9.1e-108	97.0
WP_001387718.1\|2193824_2195363_+\|tail	prophage tail fiber N-terminal domain-containing protein	A0A2D1UII2	Escherichia_phage	8.8e-54	92.2
WP_000227779.1\|2195371_2195980_+	DUF4376 domain-containing protein	Q9LA61	Enterobacterial_phage	2.2e-37	44.7
WP_071827722.1\|2196122_2196383_-	YkgJ family cysteine cluster protein	NA	NA	NA	NA
WP_001217553.1\|2196518_2196767_-	DinI-like family protein	K7PLW4	Enterobacteria_phage	1.8e-38	100.0
WP_000891610.1\|2197121_2197688_-	hydrolase	NA	NA	NA	NA
WP_001258662.1\|2197997_2199770_+\|tRNA	aspartate--tRNA ligase	NA	NA	NA	NA
WP_077221229.1\|2199762_2200215_+	dihydroneopterin triphosphate diphosphatase	NA	NA	NA	NA
WP_000907234.1\|2200243_2200984_+	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_001295503.1\|2201018_2201540_+	crossover junction endodeoxyribonuclease RuvC	G3MA90	Bacillus_virus	2.0e-10	35.1
WP_001024930.1\|2201541_2202144_-	YebB family permuted papain-like enzyme	NA	NA	NA	NA
WP_001386853.1\|2202214_2202280_+	stress response small protein YobI	NA	NA	NA	NA
WP_000580323.1\|2202418_2203030_+	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_000568519.1\|2203038_2204049_+	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	5.6e-09	25.5
WP_000571465.1\|2204195_2204981_-	zinc ABC transporter permease subunit ZnuB	NA	NA	NA	NA
WP_000202996.1\|2204977_2205733_-	zinc ABC transporter ATP-binding protein ZnuC	G3M9Y6	Bacillus_virus	1.3e-18	28.3
WP_001342995.1\|2205811_2206744_+	zinc ABC transporter substrate-binding protein ZnuA	NA	NA	NA	NA
WP_001184045.1\|2206759_2208082_+	murein DD-endopeptidase MepM	A8ATH6	Listeria_phage	1.2e-14	40.9
WP_000448381.1\|2208201_2209173_+	lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase	NA	NA	NA	NA
WP_000091176.1\|2209303_2210746_-	pyruvate kinase	NA	NA	NA	NA
WP_001056706.1\|2210873_2211743_-	DNA-binding transcriptional regulator HexR	NA	NA	NA	NA
WP_000301720.1\|2212080_2213556_+	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	9.9e-79	37.3
WP_001069467.1\|2213790_2215602_+	phosphogluconate dehydratase	NA	NA	NA	NA
WP_000800512.1\|2215638_2216280_+	bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase	NA	NA	NA	NA
WP_000173474.1\|2216335_2217514_-	formate-dependent phosphoribosylglycinamide formyltransferase	NA	NA	NA	NA
WP_000257738.1\|2217647_2217938_+	DNA damage-inducible protein YebG	NA	NA	NA	NA
WP_001295500.1\|2218004_2218361_+	protein YebF	NA	NA	NA	NA
WP_000024745.1\|2218687_2219347_+	tellurite resistance TerB family protein	NA	NA	NA	NA
WP_000936951.1\|2219555_2221616_+	oligopeptidase B	NA	NA	NA	NA
WP_000944256.1\|2221612_2222275_-	exodeoxyribonuclease X	Q6UAU3	Klebsiella_phage	2.0e-07	41.6
WP_000011658.1\|2222298_2222955_-	carbon-nitrogen hydrolase family protein	NA	NA	NA	NA
WP_000916763.1\|2223056_2223287_-	DNA polymerase III subunit theta	H9C187	Pectobacterium_phage	1.3e-14	61.8
WP_000204699.1\|2223425_2223800_+	CopC domain-containing protein YobA	NA	NA	NA	NA
WP_000879280.1\|2223803_2224676_+	copper homeostasis membrane protein CopD	NA	NA	NA	NA
WP_000976472.1\|2224688_2225030_+	YebY family protein	NA	NA	NA	NA
WP_000812712.1\|2225425_2226082_+	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	3.6e-57	50.7
WP_001296140.1\|2226082_2226274_-	YebW family protein	NA	NA	NA	NA
WP_001295499.1\|2226378_2226615_-	DUF1480 family protein	NA	NA	NA	NA
WP_000057022.1\|2226732_2228172_-	16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF	NA	NA	NA	NA
WP_001297532.1\|2228251_2230885_-	lipid-binding membrane homeostasis protein YebT	NA	NA	NA	NA
WP_001207283.1\|2230853_2232137_-	membrane integrity lipid transport subunit YebS	NA	NA	NA	NA
WP_001043882.1\|2232266_2232764_+	L-methionine (R)-S-oxide reductase	NA	NA	NA	NA
WP_000431370.1\|2232860_2233559_+	RNA chaperone ProQ	NA	NA	NA	NA
WP_001315679.1\|2233578_2235627_+	carboxy terminal-processing peptidase	A0A0R6PIZ1	Moraxella_phage	6.8e-86	33.5
WP_000984517.1\|2235818_2236700_+\|protease	protease HtpX	NA	NA	NA	NA

DBSCAN-SWA_7

2337799 : 2396379

Enterobacteria_phage(77.55%)

transposase,tail,head,capsid,plate,terminase,holin,portal,integrase,tRNA

attL 2348164:2348180|attR 2400371:2400387

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000019456.1\|2337799_2338780_-\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	2.0e-184	98.8
WP_001010722.1\|2339045_2340437_-	cystine/sulfocysteine:cation symporter	NA	NA	NA	NA
WP_001295408.1\|2340569_2341160_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_000106834.1\|2341322_2341991_-	hexitol phosphatase HxpB	NA	NA	NA	NA
WP_000222172.1\|2342137_2342674_+	YniB family protein	NA	NA	NA	NA
WP_000267645.1\|2342714_2343575_-	fructosamine kinase family protein	NA	NA	NA	NA
WP_000146159.1\|2343680_2343971_-	type V toxin-antitoxin system endoribonuclease antitoxin GhoS	NA	NA	NA	NA
WP_000251735.1\|2344071_2345001_-	6-phosphofructokinase II	NA	NA	NA	NA
WP_000771396.1\|2345287_2346046_+	YdiY family protein	NA	NA	NA	NA
WP_001142445.1\|2346098_2346206_-	hypothetical protein	NA	NA	NA	NA
2348164:2348180	attL	NA	NA	NA	NA
WP_001144190.1\|2348803_2350732_+\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	5.5e-130	37.3
WP_001700733.1\|2350735_2351278_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	6.3e-15	32.9
WP_001124225.1\|2351374_2351572_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_000124850.1\|2351624_2351981_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_001386830.1\|2352103_2352148_+	pheST operon leader peptide PheM	NA	NA	NA	NA
WP_000018588.1\|2352430_2353414_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	1.1e-33	38.5
WP_000672359.1\|2353428_2355816_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_001229265.1\|2355820_2356120_+	integration host factor subunit alpha	A0A0H3UZA0	Geobacillus_virus	7.2e-13	40.0
WP_000078916.1\|2356421_2356562_-	Hok/Gef family protein	A0A0A7NPZ4	Enterobacteria_phage	1.5e-18	97.8
WP_000488099.1\|2356752_2357013_-	ogr/Delta-like zinc finger family protein	NA	NA	NA	NA
WP_000019440.1\|2357206_2358187_-\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	6.8e-185	99.1
WP_000965749.1\|2358531_2359614_+	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_000132828.1\|2359705_2360815_-	phage late control D family protein	A0A0A7NQ97	Enterobacteria_phage	3.7e-195	94.8
WP_000005414.1\|2360972_2362157_+\|tail	phage tail sheath family protein	A0A0A7NV69	Enterobacteria_phage	3.8e-222	98.0
WP_000290443.1\|2362156_2362669_+\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	2.7e-92	98.8
WP_000665305.1\|2362723_2363089_+\|tail	tail protein	A0A0A7NPZ0	Enterobacteria_phage	1.4e-55	96.7
WP_000333498.1\|2363097_2363253_+\|tail	GpE family phage tail protein	A0A0A7NQ96	Enterobacteria_phage	3.3e-22	98.0
WP_001390260.1\|2363239_2366047_+\|tail	phage tail tape measure protein	A0A0A7NRZ9	Enterobacteria_phage	0.0e+00	92.5
WP_000979946.1\|2366059_2366548_+\|tail	phage tail protein	A0A0A7NV65	Enterobacteria_phage	8.8e-85	99.4
WP_000954195.1\|2366704_2367277_+	serine acetyltransferase	NA	NA	NA	NA
WP_000144016.1\|2367320_2367899_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	7.7e-96	89.0
WP_000108557.1\|2367898_2370031_-\|tail	phage tail protein	U5N099	Enterobacteria_phage	1.2e-130	66.4
WP_000071739.1\|2370033_2370564_-\|tail	phage tail protein I	A0A0A7NPV1	Enterobacteria_phage	1.1e-93	99.4
WP_001111965.1\|2370556_2371453_-\|plate	baseplate J/gp47 family protein	A0A0A7NPY5	Enterobacteria_phage	5.7e-154	97.3
WP_001067548.1\|2371456_2371786_-	GPW/gp25 family protein	A0A0A7NQ90	Enterobacteria_phage	2.2e-55	100.0
WP_001342219.1\|2371803_2372370_-\|plate	phage baseplate assembly protein V	A0A0A7NRZ3	Enterobacteria_phage	2.5e-99	97.3
WP_000356370.1\|2372381_2373017_-	phage virion morphogenesis protein	A0A0A7NV60	Enterobacteria_phage	5.3e-114	99.5
WP_000921128.1\|2373009_2373477_-\|tail	phage tail protein	A0A0A7NPU6	Enterobacteria_phage	2.1e-83	96.1
WP_000202135.1\|2373500_2375381_-	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	3.8e-301	81.0
WP_000780558.1\|2375519_2375927_-	DUF2570 domain-containing protein	A0A0A7NPY2	Enterobacteria_phage	1.2e-63	95.6
WP_000072317.1\|2375923_2376316_-	M15 family metallopeptidase	A0A0A7NQ86	Enterobacteria_phage	6.4e-70	97.7
WP_000104350.1\|2376312_2376636_-\|holin	phage holin family protein	A0A0A7NRY9	Enterobacteria_phage	1.6e-50	99.1
WP_000864897.1\|2376638_2376839_-\|tail	tail protein X	A0A0A7NV57	Enterobacteria_phage	6.0e-32	98.5
WP_000063103.1\|2376838_2377333_-\|head	head completion/stabilization protein	A0A0A7NPU2	Enterobacteria_phage	1.2e-89	99.4
WP_000632318.1\|2377434_2378235_-\|terminase	terminase	A0A0A7NPX9	Enterobacteria_phage	6.6e-130	91.4
WP_001055094.1\|2378280_2379333_-\|capsid	phage major capsid protein, P2 family	A0A0A7NQ82	Enterobacteria_phage	3.2e-188	94.3
WP_001262665.1\|2379356_2380193_-\|capsid	GPO family capsid scaffolding protein	A0A0A7NRY7	Enterobacteria_phage	1.8e-149	99.3
WP_000613796.1\|2380347_2382099_+	helix-turn-helix domain-containing protein	A0A0A7NV54	Enterobacteria_phage	0.0e+00	97.6
WP_000087812.1\|2382098_2383145_+\|portal	phage portal protein	A0A0A7NPT9	Enterobacteria_phage	1.5e-206	100.0
WP_000224219.1\|2383656_2383920_-	hypothetical protein	A0A2P0P958	Salmonella_phage	1.1e-30	72.4
WP_000201251.1\|2383921_2384353_-	hypothetical protein	A0A0A7NRY2	Enterobacteria_phage	4.7e-21	43.3
WP_000211292.1\|2384372_2384687_-	plasmid partitioning/stability family protein	A0A0A7NPT5	Enterobacteria_phage	3.5e-18	51.9
WP_000686540.1\|2384691_2385651_-	plasmid segregation protein ParM	A0A0A7NPX4	Enterobacteria_phage	1.3e-180	99.4
WP_001272076.1\|2385727_2388568_-	replication endonuclease	A0A0A7NQ77	Enterobacteria_phage	0.0e+00	89.4
WP_000564228.1\|2388564_2388954_-	hypothetical protein	NA	NA	NA	NA
WP_157847544.1\|2388950_2389568_-	ash family protein	S5MQL6	Escherichia_phage	1.5e-09	49.4
WP_000104300.1\|2389579_2389879_-	hypothetical protein	A0A0A7NRX6	Enterobacteria_phage	6.2e-41	88.9
WP_000153687.1\|2389875_2390121_-	winged helix-turn-helix domain-containing protein	A0A0A7NV47	Enterobacteria_phage	8.4e-36	87.7
WP_000985715.1\|2390117_2390321_-	hypothetical protein	A0A0A7NPS8	Enterobacteria_phage	3.4e-30	94.0
WP_001038613.1\|2390310_2390631_-	hypothetical protein	NA	NA	NA	NA
WP_000021658.1\|2390719_2390833_-	hypothetical protein	A0A0A7NPW7	Enterobacteria_phage	1.4e-09	91.9
WP_000514277.1\|2390829_2391072_-	DUF4754 family protein	A0A0A7NQ71	Enterobacteria_phage	2.3e-38	100.0
WP_000159452.1\|2391083_2391371_-	hypothetical protein	A0A0A7NRX5	Enterobacteria_phage	2.7e-33	77.9
WP_000917807.1\|2391381_2391720_-	DUF4761 family protein	A0A0A7NV42	Enterobacteria_phage	2.2e-50	85.3
WP_000163908.1\|2391734_2392013_-	DNA-binding protein	NA	NA	NA	NA
WP_000094527.1\|2392104_2392416_+	helix-turn-helix transcriptional regulator	Q1JS45	Enterobacteria_phage	8.8e-22	55.9
WP_001247218.1\|2392504_2393440_+\|integrase	tyrosine-type recombinase/integrase	A0A0M4RTQ0	Salmonella_phage	4.8e-79	50.5
WP_000416308.1\|2393450_2393846_+	hypothetical protein	NA	NA	NA	NA
WP_000956518.1\|2394035_2395016_+	vitamin B12 ABC transporter permease BtuC	NA	NA	NA	NA
WP_001154183.1\|2395078_2395630_+	bifunctional thioredoxin/glutathione peroxidase	NA	NA	NA	NA
WP_000029466.1\|2395629_2396379_+	vitamin B12 ABC transporter ATP-binding protein BtuD	A0A2R8FG22	Brazilian_cedratvirus	9.3e-09	28.2
2400371:2400387	attR	NA	NA	NA	NA

DBSCAN-SWA_8

2516028 : 2590661

Shigella_phage(43.48%)

tail,capsid,protease,lysis,terminase,holin,portal,integrase

attL 2520132:2520149|attR 2548182:2548199

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001260841.1\|2516028_2516850_-\|protease	serine protease	NA	NA	NA	NA
WP_000233090.1\|2516949_2517033_-	hypothetical protein	NA	NA	NA	NA
WP_000743951.1\|2517125_2517461_-	acid shock protein	NA	NA	NA	NA
WP_000091806.1\|2517857_2519111_-	MFS transporter	NA	NA	NA	NA
WP_001019532.1\|2519217_2520111_+	LysR family transcriptional regulator	NA	NA	NA	NA
2520132:2520149	attL	NA	NA	NA	NA
WP_000225276.1\|2520245_2521466_+	DNA-binding transcriptional repressor Mlc	NA	NA	NA	NA
WP_000919231.1\|2521590_2522286_+	ATP-dependent dethiobiotin synthetase BioD	NA	NA	NA	NA
WP_071820512.1\|2522301_2523531_-	voltage-gated ClC-type chloride channel ClcB	NA	NA	NA	NA
WP_000148710.1\|2523689_2524304_-	Tat proofreading chaperone DmsD	A0A077SLS7	Escherichia_phage	8.7e-29	36.3
WP_000526492.1\|2524346_2525201_-	dimethyl sulfoxide reductase anchor subunit	NA	NA	NA	NA
WP_001387389.1\|2525794_2526958_-\|integrase	site-specific integrase	A0A088CD23	Shigella_phage	3.8e-227	99.7
WP_000497813.1\|2527219_2527471_-	DUF4222 domain-containing protein	A0A088CBN9	Shigella_phage	1.3e-39	100.0
WP_000186868.1\|2527518_2528199_-	YqaJ viral recombinase family protein	A0A0P0ZBV6	Stx2-converting_phage	1.5e-130	98.2
WP_000100829.1\|2528195_2528981_-	phage recombination protein Bet	A0A088CBI3	Shigella_phage	9.4e-145	97.3
WP_000995032.1\|2528986_2529283_-	host-nuclease inhibitor protein Gam	V5URU8	Shigella_phage	5.8e-47	93.9
WP_001271588.1\|2529279_2531352_-	exodeoxyribonuclease VIII	V5UQJ3	Shigella_phage	0.0e+00	87.4
WP_000660961.1\|2531459_2531846_-	hypothetical protein	V5USC5	Shigella_phage	9.5e-50	78.9
WP_000560214.1\|2531929_2532151_-	cell division protein FtsZ	A0A0U2RTC4	Escherichia_phage	1.1e-34	94.4
WP_000189936.1\|2532607_2532817_+	hypothetical protein	NA	NA	NA	NA
WP_001005963.1\|2532785_2533145_-	hypothetical protein	A0A088CBI5	Shigella_phage	2.3e-37	72.6
WP_000211196.1\|2533176_2533890_-	hypothetical protein	A0A088CC14	Shigella_phage	1.8e-126	98.7
WP_000198438.1\|2533893_2534277_-	antitermination protein	G9L671	Escherichia_phage	6.7e-64	99.2
WP_000528776.1\|2534771_2535548_-	DUF1828 domain-containing protein	NA	NA	NA	NA
WP_001074607.1\|2535535_2536078_-	hypothetical protein	NA	NA	NA	NA
WP_001274758.1\|2536124_2536838_-	LexA family transcriptional regulator	A4KWV9	Enterobacteria_phage	4.1e-131	99.6
WP_000437871.1\|2536938_2537139_+	Cro/Cl family transcriptional regulator	A4KWT7	Enterobacteria_phage	1.3e-29	97.0
WP_000438525.1\|2537277_2537574_+	hypothetical protein	A0A088CBI6	Shigella_phage	3.4e-47	98.0
WP_000438870.1\|2537588_2537807_+	hypothetical protein	A0A088CC17	Shigella_phage	1.1e-21	100.0
WP_001390256.1\|2537827_2538910_+	hypothetical protein	V5URT9	Shigella_phage	2.8e-200	96.4
WP_000790392.1\|2538916_2539657_+	ATP-binding protein	A0A088CBP4	Shigella_phage	2.3e-121	87.4
WP_000450864.1\|2539682_2540453_+	DUF1627 domain-containing protein	A0A088CE47	Shigella_phage	8.1e-109	82.4
WP_001118163.1\|2540468_2540864_+	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	2.0e-31	52.9
WP_000206792.1\|2540920_2541505_+	DUF551 domain-containing protein	A0A0P0ZD75	Stx2-converting_phage	5.5e-33	83.5
WP_001278450.1\|2541620_2541725_+	hypothetical protein	NA	NA	NA	NA
WP_000887482.1\|2541913_2542126_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	8.4e-16	62.9
WP_000119356.1\|2542335_2542515_+	hypothetical protein	NA	NA	NA	NA
WP_000818160.1\|2542533_2543019_+	type II toxin-antitoxin system death-on-curing family toxin	NA	NA	NA	NA
WP_000042397.1\|2543069_2543387_-	DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_000211990.1\|2544093_2544765_+	ORF6N domain-containing protein	A0A088CD42	Shigella_phage	9.0e-96	82.6
WP_001076834.1\|2544819_2545230_+	recombination protein NinB	A0A088CBP6	Shigella_phage	3.9e-70	98.5
WP_001254268.1\|2545226_2545418_+	NinE family protein	A0A0P0ZDL7	Stx2-converting_phage	8.9e-25	87.7
WP_000002252.1\|2545441_2545732_+	DUF1364 domain-containing protein	A0A088CE53	Shigella_phage	9.3e-50	96.9
WP_001008115.1\|2545728_2546091_+	RusA family crossover junction endodeoxyribonuclease	A0A088CBJ1	Shigella_phage	9.2e-63	98.3
WP_000992060.1\|2546090_2546285_+	protein ninH	A0A088CC23	Shigella_phage	1.4e-30	100.0
WP_001204886.1\|2546277_2546712_+	antitermination protein	G9L695	Escherichia_phage	2.4e-81	98.6
WP_000874468.1\|2547477_2549388_+	SASA family carbohydrate esterase	A0A0N7CGH9	Escherichia_phage	6.4e-280	74.8
2548182:2548199	attR	NA	NA	NA	NA
WP_000142783.1\|2549526_2549709_+	DUF1378 family protein	S5MBZ5	Escherichia_phage	1.6e-23	91.7
WP_001290236.1\|2549734_2549980_+	DUF826 domain-containing protein	S5MW40	Escherichia_phage	1.1e-14	87.7
WP_000284506.1\|2550056_2550272_+\|holin	class II holin family protein	Q9ZWW2	Enterobacteria_phage	6.9e-34	100.0
WP_000087450.1\|2550276_2550810_+	lysozyme	A0A088CC28	Shigella_phage	5.6e-93	91.5
WP_000675931.1\|2551030_2551144_+	hypothetical protein	A0A2L1IV24	Escherichia_phage	6.6e-12	100.0
WP_001082713.1\|2551145_2551604_+\|lysis	lysis protein	A0A2L1IV55	Escherichia_phage	6.4e-77	99.3
WP_000934362.1\|2551684_2552266_-	lipopolysaccharide core heptose(II)-phosphate phosphatase	A0A2L1IV13	Escherichia_phage	6.7e-47	100.0
WP_001086085.1\|2552868_2553684_+\|terminase	terminase	A0A2L1IV66	Escherichia_phage	6.6e-125	99.6
WP_001387707.1\|2553664_2555371_+\|terminase	terminase	A0A2L1IV76	Escherichia_phage	0.0e+00	99.1
WP_000787512.1\|2555370_2557515_+\|portal	portal protein	A0A088CE71	Shigella_phage	0.0e+00	99.6
WP_000344999.1\|2557672_2558680_+	hypothetical protein	A0A2L1IV47	Escherichia_phage	1.2e-168	93.4
WP_000214480.1\|2558702_2559917_+\|capsid	N4-gp56 family major capsid protein	A0A2L1IV46	Escherichia_phage	1.8e-232	99.0
WP_001140435.1\|2559971_2560361_+	hypothetical protein	V5UT93	Shigella_phage	1.9e-61	97.7
WP_001290749.1\|2560411_2560873_+	hypothetical protein	A0A2L1IV43	Escherichia_phage	6.9e-71	99.3
WP_000829400.1\|2560856_2561420_+	hypothetical protein	A0A2L1IV64	Escherichia_phage	8.3e-103	99.5
WP_000207910.1\|2561419_2562070_+	hypothetical protein	A0A2L1IV63	Escherichia_phage	1.5e-119	99.1
WP_000117962.1\|2562066_2563974_+\|tail	tail fiber protein	V5USF3	Shigella_phage	4.2e-82	66.0
WP_000537686.1\|2564056_2564602_+	hypothetical protein	A0A088CD67	Shigella_phage	2.0e-93	99.4
WP_000276176.1\|2564614_2564842_+	hypothetical protein	A0A088CBQ7	Shigella_phage	2.6e-39	98.7
WP_001146337.1\|2565182_2566808_+	hypothetical protein	A0A1I9LJT3	Stx_converting_phage	0.0e+00	96.7
WP_000038927.1\|2566804_2568073_+	host specificity protein J	A0A0N7C124	Escherichia_phage	1.6e-218	94.3
WP_000455633.1\|2568087_2568366_+	outer membrane protein	A0A2L1IV69	Escherichia_phage	2.6e-49	100.0
WP_001390575.1\|2568371_2568989_+	hypothetical protein	A0A2L1IV83	Escherichia_phage	6.3e-120	98.0
WP_000836186.1\|2569068_2569806_+	Ail/Lom family outer membrane beta-barrel protein	A0A2L1IV31	Escherichia_phage	1.2e-109	80.8
WP_000078908.1\|2570040_2570181_+	Hok/Gef family protein	A0A2R2X2B4	Escherichia_phage	2.0e-18	97.8
WP_001387532.1\|2570237_2570639_+	hypothetical protein	Q08J75	Stx2-converting_phage	5.0e-70	98.5
WP_000509022.1\|2570730_2571387_+	hypothetical protein	A0A0H4IPM7	Shigella_phage	7.4e-103	99.1
WP_000455643.1\|2571389_2571836_+	hypothetical protein	A0A2L1IV89	Escherichia_phage	4.0e-76	100.0
WP_000540395.1\|2571845_2572097_+	hypothetical protein	A0A0P0ZDW9	Stx2-converting_phage	7.9e-13	97.5
WP_000012439.1\|2572107_2573373_+	hypothetical protein	A0A2L1IV65	Escherichia_phage	1.5e-192	95.0
WP_000331660.1\|2573441_2581793_+	hypothetical protein	Q08J70	Stx2-converting_phage	0.0e+00	95.8
WP_000481378.1\|2581916_2582192_+	hypothetical protein	A0A088CD78	Shigella_phage	4.0e-18	89.3
WP_000628768.1\|2582193_2582697_-	DUF551 domain-containing protein	V5UT79	Shigella_phage	2.6e-95	98.2
WP_001290012.1\|2583210_2584047_-	ead/Ea22-like family protein	A0A2I6TD51	Escherichia_phage	6.1e-126	87.7
WP_000020909.1\|2584033_2584318_-	DUF4752 family protein	A0A088CD82	Shigella_phage	6.1e-46	98.9
WP_000763355.1\|2584314_2584536_-	TraR/DksA family transcriptional regulator	V5USD3	Shigella_phage	2.9e-35	98.6
WP_000184488.1\|2584583_2585219_-	phage antirepressor Ant	A0A088CBR4	Shigella_phage	2.8e-91	81.0
WP_001342404.1\|2585750_2588174_-	dimethyl sulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	9.8e-209	48.6
WP_000041536.1\|2588234_2590661_-	dimethyl sulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	2.3e-213	49.1

DBSCAN-SWA_9

2878509 : 2939977

Enterobacteria_phage(41.18%)

tail,capsid,protease,terminase,holin,portal,integrase,head

attL 2923209:2923223|attR 2944148:2944162

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000422045.1\|2878509_2879559_-\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	1.3e-21	31.5
WP_000559283.1\|2879778_2880537_+	YciK family oxidoreductase	A0A0N9R355	Chrysochromulina_ericina_virus	8.8e-07	23.4
WP_001278904.1\|2880533_2881124_+	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_001291216.1\|2881163_2882036_-	23S rRNA pseudouridine(2605) synthase RluB	NA	NA	NA	NA
WP_001295575.1\|2882136_2882757_-	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_001285661.1\|2882753_2883635_-	5'-3' exoribonuclease	NA	NA	NA	NA
WP_001386774.1\|2883772_2883817_+	trp operon leader peptide	NA	NA	NA	NA
WP_001194599.1\|2883908_2885471_+	anthranilate synthase component I	NA	NA	NA	NA
WP_000763511.1\|2885470_2887066_+	bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD	A0A0N7IRD9	Acinetobacter_phage	3.8e-52	38.5
WP_000983912.1\|2887066_2888428_+	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	A0A0P0IR83	Acinetobacter_phage	1.1e-36	40.2
WP_000209520.1\|2888439_2889633_+	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_000443069.1\|2889632_2890439_+	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_000807651.1\|2890819_2890999_+	general stress protein	NA	NA	NA	NA
WP_001056491.1\|2891084_2891585_+	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_001079509.1\|2891630_2892137_+	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_000251936.1\|2892625_2892796_-	hypothetical protein	A0A0U2RK60	Escherichia_phage	9.4e-10	62.5
WP_000926528.1\|2892910_2893180_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	2.7e-19	77.8
WP_000240999.1\|2893236_2893905_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000885576.1\|2893959_2894544_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	1.7e-103	95.4
WP_000216502.1\|2894543_2897378_-\|tail	prophage tail fiber N-terminal domain-containing protein	X2KTY7	Enterobacteria_phage	5.7e-83	59.1
WP_001228314.1\|2897529_2898129_-	Ail/Lom family protein	Q9EV15	Enterobacteria_phage	9.1e-108	97.0
WP_000515776.1\|2898196_2901676_-	host specificity protein J	A5LH43	Enterobacteria_phage	0.0e+00	89.6
WP_001332187.1\|2901742_2902081_-	hypothetical protein	NA	NA	NA	NA
WP_000090879.1\|2902154_2902757_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	6.2e-88	85.1
WP_000140761.1\|2902693_2903437_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	1.8e-145	94.7
WP_001152522.1\|2903441_2904140_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	3.4e-130	97.4
WP_000847379.1\|2904139_2904469_-\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	9.6e-59	100.0
WP_000082359.1\|2904465_2907039_-\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	83.9
WP_000533402.1\|2907019_2907433_-\|tail	phage tail assembly protein T	S5MDP5	Escherichia_phage	1.6e-42	82.2
WP_000479095.1\|2907459_2907891_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	6.2e-42	68.8
WP_000683079.1\|2908662_2909058_-\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	1.5e-58	82.4
WP_000974999.1\|2909054_2909630_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	9.2e-49	57.3
WP_001204198.1\|2909644_2909998_-\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	3.0e-42	70.1
WP_000201506.1\|2909990_2910359_-	hypothetical protein	NA	NA	NA	NA
WP_000522596.1\|2910410_2911439_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	2.8e-112	60.4
WP_000256823.1\|2911496_2911844_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	8.9e-23	58.1
WP_014966177.1\|2911880_2913386_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.8e-99	53.1
WP_014966178.1\|2913375_2914968_-\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	3.2e-184	60.9
WP_000259002.1\|2914964_2915171_-\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	7.9e-11	56.9
WP_001390573.1\|2915154_2917083_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	1.6e-262	67.5
WP_000867569.1\|2917054_2917603_-\|terminase	terminase small subunit	A0A0U2S671	Escherichia_phage	1.0e-57	84.2
WP_000240372.1\|2918003_2918408_-	hypothetical protein	NA	NA	NA	NA
WP_000343118.1\|2918861_2919149_-	hypothetical protein	A0A1P8DTP0	Salmonella_phage	4.0e-29	58.9
WP_001390467.1\|2919227_2919380_-	hypothetical protein	K7PKL2	Enterobacteria_phage	2.8e-21	98.0
WP_001228710.1\|2919408_2919615_-	hypothetical protein	H6WRZ6	Salmonella_phage	2.9e-29	95.6
WP_032159578.1\|2919836_2919923_-	hypothetical protein	NA	NA	NA	NA
WP_001092853.1\|2920477_2921011_-	lysozyme	Q6H9V6	Enterobacteria_phage	8.7e-102	97.2
WP_000731197.1\|2921053_2921860_-	YdfR family protein	Q08JA0	Stx2-converting_phage	3.3e-145	94.8
WP_000284510.1\|2921864_2922080_-\|holin	class II holin family protein	G9L6J5	Escherichia_phage	9.0e-34	100.0
WP_000874307.1\|2922230_2924084_-	SASA family carbohydrate esterase	Q08JA2	Stx2-converting_phage	0.0e+00	90.5
2923209:2923223	attL	NA	NA	NA	NA
WP_000871291.1\|2924344_2924680_+	anti-adapter protein IraM	Q8HAJ1	Enterobacteria_phage	5.2e-44	74.8
WP_001438304.1\|2924960_2925092_-	DUF3927 family protein	H6WZJ7	Escherichia_phage	1.1e-05	96.4
WP_000935536.1\|2925890_2926940_-	site-specific DNA-methyltransferase	A0A0N7KZF8	Stx2-converting_phage	8.8e-199	95.7
WP_000917746.1\|2927090_2927288_-	hypothetical protein	Q9MC00	Enterobacteria_phage	1.4e-28	96.9
WP_000762880.1\|2927514_2928336_-	antitermination protein	K7P7B9	Enterobacteria_phage	8.5e-80	60.1
WP_000904106.1\|2928332_2928707_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	5.8e-36	63.6
WP_001265083.1\|2928719_2929766_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	5.9e-110	55.0
WP_001329966.1\|2929767_2930040_-	hypothetical protein	I6PCV7	Cronobacter_phage	5.5e-12	49.2
WP_000018429.1\|2930207_2930420_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	5.2e-26	90.0
WP_000150294.1\|2930600_2931266_-	epoxyqueuosine reductase QueH	NA	NA	NA	NA
WP_001151211.1\|2931440_2931866_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	1.3e-63	94.0
WP_000095671.1\|2931906_2932869_-	helix-turn-helix domain-containing protein	U5P0A0	Shigella_phage	2.1e-69	51.2
WP_000693888.1\|2932891_2933317_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_001072337.1\|2933313_2933568_-	hypothetical protein	A0A2I6PIE5	Escherichia_phage	2.8e-18	60.3
WP_000233320.1\|2933647_2934067_+	helix-turn-helix domain-containing protein	A0A2I6PIE7	Escherichia_phage	4.2e-19	47.5
WP_000379548.1\|2934363_2934516_+	DUF1391 family protein	M4QQ57	Salicola_phage	6.0e-08	55.3
WP_000394541.1\|2934527_2934866_+	hypothetical protein	A0A2R2Z306	Escherichia_phage	2.5e-06	51.0
WP_012601410.1\|2934854_2935121_-	hypothetical protein	NA	NA	NA	NA
WP_000449192.1\|2935615_2935804_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001090200.1\|2935800_2935992_+	DUF1482 family protein	NA	NA	NA	NA
WP_000048530.1\|2936084_2938556_+	exonuclease	K7PLW7	Enterobacteria_phage	1.8e-56	59.2
WP_000113189.1\|2938620_2938869_+	excisionase	NA	NA	NA	NA
WP_000113686.1\|2938846_2939977_+\|integrase	phage integrase Arm DNA-binding domain-containing protein	O21940	Phage_21	4.4e-103	51.4
2944148:2944162	attR	NA	NA	NA	NA

DBSCAN-SWA_10

3225182 : 3316983

Escherichia_phage(88.16%)

transposase,tail,capsid,lysis,terminase,bacteriocin,holin,portal,integrase

attL 3223719:3223736|attR 3276961:3276978

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3223719:3223736	attL	NA	NA	NA	NA
WP_000279857.1\|3225182_3226400_-\|integrase	tyrosine-type recombinase/integrase	A0A1B0VMI6	Pseudomonas_phage	6.5e-44	34.7
WP_000611858.1\|3226947_3227934_-	hypothetical protein	NA	NA	NA	NA
WP_000627404.1\|3227930_3228422_-	ACP S-malonyltransferase	NA	NA	NA	NA
WP_085948466.1\|3228524_3229686_+\|transposase	IS3-like element IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.1e-51	40.6
WP_000409841.1\|3229727_3231086_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	1.1e-20	33.0
WP_000287459.1\|3231672_3234096_+	poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA	NA	NA	NA	NA
WP_000945561.1\|3234104_3236123_+	poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB	NA	NA	NA	NA
WP_000610451.1\|3236115_3237441_+	poly-beta-1,6 N-acetyl-D-glucosamine synthase	NA	NA	NA	NA
WP_001061095.1\|3237442_3237856_+	poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD	NA	NA	NA	NA
WP_000533522.1\|3237905_3238694_-	phosphate starvation-inducible protein PhoH	R4II13	Cronobacter_phage	7.8e-91	76.7
WP_001199172.1\|3239312_3240584_-	deferrochelatase/peroxidase EfeB	NA	NA	NA	NA
WP_000154414.1\|3240589_3241717_-	iron uptake system protein EfeO	NA	NA	NA	NA
WP_000497942.1\|3241774_3242605_-	FTR1 family protein	NA	NA	NA	NA
WP_001018486.1\|3243146_3244655_-	sodium/proline symporter PutP	NA	NA	NA	NA
WP_000979516.1\|3244813_3245023_-	hypothetical protein	NA	NA	NA	NA
WP_001299828.1\|3245077_3249040_+	trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_000191700.1\|3249079_3249718_-	HTH-type transcriptional regulator RutR	NA	NA	NA	NA
WP_001297176.1\|3250005_3251097_+	pyrimidine utilization protein A	NA	NA	NA	NA
WP_001307708.1\|3251096_3251789_+	peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB	NA	NA	NA	NA
WP_001126777.1\|3251800_3252187_+	pyrimidine utilization protein C	NA	NA	NA	NA
WP_001307099.1\|3252194_3252995_+	pyrimidine utilization protein D	NA	NA	NA	NA
WP_001001196.1\|3253004_3253595_+	malonic semialdehyde reductase	NA	NA	NA	NA
WP_001028096.1\|3253605_3254100_+	pyrimidine utilization flavin reductase protein F	Q9KX93	Enterobacteria_phage	1.1e-50	96.9
WP_001326838.1\|3254120_3255449_+	pyrimidine utilization transport protein G	Q9KX94	Enterobacteria_phage	3.7e-234	99.1
WP_001273658.1\|3255531_3255705_-	general stress protein	Q9KX95	Enterobacteria_phage	4.9e-06	96.3
WP_000331685.1\|3256636_3265018_-	hypothetical protein	A0A0P0ZFK4	Escherichia_phage	0.0e+00	100.0
WP_000012452.1\|3265087_3266353_-	hypothetical protein	A0A0P0ZFI5	Escherichia_phage	2.4e-206	100.0
WP_000540391.1\|3266363_3266615_-\|bacteriocin	bacteriocin	A0A2R2Z351	Escherichia_phage	7.9e-13	100.0
WP_000455649.1\|3266624_3267071_-	hypothetical protein	A0A2R2Z357	Escherichia_phage	6.2e-77	100.0
WP_000509489.1\|3267073_3267730_-	hypothetical protein	A0A0P0ZGB7	Escherichia_phage	2.4e-109	100.0
WP_000035558.1\|3267823_3268225_-	hypothetical protein	A0A2R2Z359	Escherichia_phage	3.7e-73	100.0
WP_000078907.1\|3268281_3268422_-	Hok/Gef family protein	A0A2R2X2B4	Escherichia_phage	3.1e-19	100.0
WP_000835360.1\|3268654_3269389_-	Ail/Lom family outer membrane beta-barrel protein	A0A2R2Z365	Escherichia_phage	1.3e-135	100.0
WP_001301884.1\|3269479_3270097_-	hypothetical protein	A0A2R2Z362	Escherichia_phage	1.1e-121	100.0
WP_000455634.1\|3270102_3270381_-	outer membrane protein	A0A2R2Z367	Escherichia_phage	1.1e-50	100.0
WP_000197192.1\|3270395_3271664_-	host specificity protein J	A0A2R2Z364	Escherichia_phage	4.9e-220	100.0
WP_001391593.1\|3271660_3273286_-	hypothetical protein	A0A0P0ZG21	Escherichia_phage	0.0e+00	100.0
WP_000513231.1\|3273519_3274032_-	receptor recognizing protein Gp38	A0A0P0ZFL3	Escherichia_phage	1.2e-92	100.0
WP_000117967.1\|3274118_3276311_-\|tail	tail fiber protein	A0A0H4IU95	Shigella_phage	1.9e-86	98.0
WP_000207927.1\|3276307_3276958_-	hypothetical protein	A0A0P0ZGL1	Escherichia_phage	4.6e-121	100.0
WP_000829200.1\|3276957_3277521_-	hypothetical protein	A0A2R2Z349	Escherichia_phage	3.2e-102	100.0
3276961:3276978	attR	NA	NA	NA	NA
WP_001367376.1\|3277504_3277966_-	hypothetical protein	A0A0P0ZG73	Escherichia_phage	6.0e-75	100.0
WP_001140442.1\|3278015_3278405_-	hypothetical protein	A0A2R2Z353	Escherichia_phage	9.9e-63	100.0
WP_000214474.1\|3278460_3279675_-\|capsid	N4-gp56 family major capsid protein	A0A2R2Z358	Escherichia_phage	1.3e-233	100.0
WP_000345010.1\|3279698_3280706_-	hypothetical protein	A0A2R2Z355	Escherichia_phage	2.3e-180	100.0
WP_000787034.1\|3280863_3283008_-\|portal	portal protein	A0A0P0ZG74	Escherichia_phage	0.0e+00	100.0
WP_000143988.1\|3283007_3284714_-\|terminase	terminase	A0A2R2Z350	Escherichia_phage	0.0e+00	100.0
WP_001086073.1\|3284694_3285501_-\|terminase	terminase	A0A0P0ZG40	Escherichia_phage	1.3e-133	100.0
WP_001109019.1\|3285793_3286345_-	Rha family transcriptional regulator	A0A0P0ZFJ1	Escherichia_phage	4.5e-101	100.0
WP_024017835.1\|3286547_3286985_-\|lysis	lysis protein	A0A0P0ZFH2	Escherichia_phage	1.4e-70	100.0
WP_000455397.1\|3286987_3287137_-	hypothetical protein	A0A0P0ZG36	Escherichia_phage	4.8e-18	100.0
WP_001056879.1\|3287136_3287706_-	hypothetical protein	A0A0N7KZV8	Escherichia_phage	1.8e-105	100.0
WP_000087737.1\|3287979_3288513_-	lysozyme	A0A0P0ZGA2	Escherichia_phage	5.1e-102	100.0
WP_001072901.1\|3288517_3288733_-\|holin	class II holin family protein	A0A2R2Z340	Escherichia_phage	1.2e-33	100.0
WP_001290230.1\|3288810_3289056_-	DUF826 domain-containing protein	A0A0P0ZGR2	Escherichia_phage	8.8e-17	100.0
WP_000143458.1\|3289096_3289276_-	DUF1378 family protein	A0A2R2Z345	Escherichia_phage	2.2e-25	100.0
WP_000874432.1\|3289412_3291350_-	SASA family carbohydrate esterase	A0A0P0ZGE0	Escherichia_phage	0.0e+00	100.0
WP_000738068.1\|3291835_3292105_-	Shiga toxin Stx2a subunit B	A0A2R2Z326	Escherichia_phage	1.2e-43	100.0
WP_000649753.1\|3292116_3293076_-	Shiga toxin Stx2c subunit A	Q776Q3	Enterobacteria_phage	5.6e-176	100.0
WP_001356551.1\|3293458_3293611_-	DNA methylase	A0A2R2Z327	Escherichia_phage	4.0e-20	100.0
WP_001204859.1\|3293859_3294294_-	antitermination protein	A0A0P0ZGJ3	Escherichia_phage	4.8e-82	100.0
WP_000144767.1\|3294286_3294481_-	phage NinH family protein	A0A0P0ZGE1	Escherichia_phage	8.4e-31	100.0
WP_000813671.1\|3294477_3295041_-	recombination protein NinG	A0A0P0ZG59	Escherichia_phage	8.9e-105	100.0
WP_000402092.1\|3295048_3295498_-	DUF1367 family protein	A0A0P0ZFW0	Escherichia_phage	7.6e-83	100.0
WP_001260358.1\|3295497_3296469_-	toprim domain-containing protein	A0A0P0ZFY3	Escherichia_phage	6.5e-196	100.0
WP_000913116.1\|3296458_3297979_-	DEAD/DEAH box helicase	A0A0N7KZV6	Escherichia_phage	1.4e-306	100.0
WP_001271433.1\|3297972_3298350_-	hypothetical protein	A0A2R2Z329	Escherichia_phage	4.0e-61	100.0
WP_001369601.1\|3298516_3298711_-	hypothetical protein	NA	NA	NA	NA
WP_001240876.1\|3298881_3299085_-	Cro/Cl family transcriptional regulator	A0A2R2Z333	Escherichia_phage	2.0e-30	100.0
WP_001056250.1\|3299180_3299894_+	LexA family transcriptional regulator	A0A2R2X2B0	Escherichia_phage	6.3e-132	100.0
WP_000939558.1\|3299988_3301458_+	Eco57I restriction-modification methylase domain-containing protein	A0A2R2Z316	Escherichia_phage	3.5e-286	100.0
WP_001064714.1\|3301454_3302408_+	type II restriction endonuclease BsuBI	A0A0P0ZG22	Escherichia_phage	7.0e-187	100.0
WP_016051777.1\|3303024_3303810_+	Rha family transcriptional regulator	A0A0P0ZG86	Escherichia_phage	9.4e-145	100.0
WP_001369605.1\|3304065_3304740_+	ORF6N domain-containing protein	A0A0P0ZGP9	Escherichia_phage	1.3e-123	100.0
WP_000917252.1\|3304810_3305023_+	cell division inhibitor protein	A0A0P0ZGD1	Escherichia_phage	5.8e-33	100.0
WP_000934197.1\|3305034_3305316_+	hypothetical protein	A0A0P0ZGC3	Escherichia_phage	3.0e-45	100.0
WP_000995345.1\|3305336_3305618_+	host nuclease inhibitor GamL	A0A0P0ZFG3	Escherichia_phage	1.1e-47	100.0
WP_000459721.1\|3305634_3306585_+	recombinase RecT	A0A0P0ZFY9	Escherichia_phage	1.1e-179	100.0
WP_000187063.1\|3306581_3307271_+	YqaJ viral recombinase family protein	A0A0P0ZFI7	Escherichia_phage	3.5e-135	100.0
WP_000344637.1\|3307270_3307858_+	hypothetical protein	A0A0N7KZV4	Escherichia_phage	1.2e-107	100.0
WP_001071603.1\|3307932_3308280_+	hypothetical protein	A0A0P0ZGH3	Escherichia_phage	5.9e-59	100.0
WP_000080417.1\|3308343_3309165_+	DUF2303 family protein	A0A2R2Z323	Escherichia_phage	2.3e-149	100.0
WP_001159715.1\|3309241_3309637_+	hypothetical protein	A0A0P0ZG44	Escherichia_phage	1.1e-69	100.0
WP_000206047.1\|3309787_3310513_+	ead/Ea22-like family protein	A0A0P0ZFU9	Escherichia_phage	3.3e-128	100.0
WP_000034212.1\|3310509_3310917_+	ead/Ea22-like family protein	A0A125RPT9	Escherichia_phage	1.3e-70	100.0
WP_001014298.1\|3310918_3311110_+	hypothetical protein	A0A0P0ZG45	Escherichia_phage	3.3e-27	100.0
WP_000206786.1\|3311112_3312009_+	DUF551 domain-containing protein	A0A0N7KZV3	Escherichia_phage	5.4e-173	100.0
WP_000203831.1\|3312364_3313003_+	phage antirepressor Ant	A0A0P0ZG08	Escherichia_phage	4.2e-119	100.0
WP_000809302.1\|3313058_3313490_+	hypothetical protein	A0A2R2Z303	Escherichia_phage	7.3e-75	100.0
WP_000163446.1\|3313486_3314113_+	adenine methylase	A0A0P0ZG10	Escherichia_phage	8.0e-123	100.0
WP_001291842.1\|3314072_3314285_+	DUF1382 family protein	A0A0P0ZG72	Escherichia_phage	2.7e-30	100.0
WP_000994790.1\|3314320_3314674_+	DUF1627 domain-containing protein	A0A0P0ZH73	Escherichia_phage	3.5e-59	100.0
WP_000497815.1\|3315038_3315290_+	DUF4222 domain-containing protein	G9L6F5	Escherichia_phage	8.4e-39	100.0
WP_001208773.1\|3315335_3315620_+	excisionase family protein	G9L654	Escherichia_phage	9.1e-50	100.0
WP_000013658.1\|3315672_3316983_+	DUF3596 domain-containing protein	A0A0P0ZGA8	Escherichia_phage	9.2e-254	100.0

DBSCAN-SWA_11

3527799 : 3624335

107

Enterobacteria_phage(44.62%)

transposase,tail,capsid,lysis,portal,integrase,head

attL 3554083:3554117|attR 3625769:3625803

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000399648.1\|3527799_3528780_-\|transposase	IS110-like element IS621 family transposase	NA	NA	NA	NA
WP_000961458.1\|3529058_3530651_-	ABC-F family ATPase	A0A2K9L0W2	Tupanvirus	6.9e-62	28.7
WP_001056384.1\|3530869_3531790_+	L,D-transpeptidase	NA	NA	NA	NA
WP_000056442.1\|3531848_3532967_-	anion transporter	NA	NA	NA	NA
WP_000091016.1\|3532963_3533431_-	manganese-binding transcriptional regulator MntR	NA	NA	NA	NA
WP_001001761.1\|3533616_3533745_+	manganase accumulation protein MntS	NA	NA	NA	NA
WP_001054697.1\|3534016_3535600_+	phosphoethanolamine transferase	NA	NA	NA	NA
WP_001295296.1\|3535648_3536164_-	outer membrane protein OmpX	H6WZM8	Escherichia_phage	1.1e-16	33.8
WP_120795379.1\|3536216_3536282_-	protein YliM	NA	NA	NA	NA
WP_001119538.1\|3536516_3537404_+	threonine/homoserine exporter RhtA	NA	NA	NA	NA
WP_000100800.1\|3537702_3538206_+	DNA starvation/stationary phase protection protein Dps	A0A222YYG6	Streptomyces_phage	4.9e-06	29.0
WP_000843866.1\|3538609_3539356_+	glutamine ABC transporter substrate-binding protein GlnH	NA	NA	NA	NA
WP_001159065.1\|3539494_3540154_+	glutamine ABC transporter permease GlnP	NA	NA	NA	NA
WP_000569080.1\|3540150_3540873_+	glutamine ABC transporter ATP-binding protein GlnQ	G9BWD6	Planktothrix_phage	2.5e-35	41.8
WP_001267242.1\|3540989_3543215_+	mechanosensitive channel protein	NA	NA	NA	NA
WP_001387659.1\|3543211_3544138_-	23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF	NA	NA	NA	NA
WP_001387658.1\|3544413_3544674_+	DUF1471 domain-containing protein	A0A1B2ICL8	Erwinia_phage	1.6e-05	51.0
WP_000430039.1\|3544938_3547221_+	catecholate siderophore receptor Fiu	NA	NA	NA	NA
WP_000990161.1\|3547262_3547940_+	PKHD-type hydroxylase YbiX	Q5GQB0	Synechococcus_phage	3.1e-19	30.1
WP_000146343.1\|3548013_3548280_+	C4-type zinc finger protein YbiI	E5G6L7	Salmonella_phage	6.9e-07	45.6
WP_000849301.1\|3548544_3548805_+	DUF1471 domain-containing protein	NA	NA	NA	NA
WP_000443512.1\|3549033_3550119_-	hydroxycarboxylate dehydrogenase HcXB	NA	NA	NA	NA
WP_000386540.1\|3550259_3551222_-	DNA-binding protein YbiB	NA	NA	NA	NA
WP_001340191.1\|3551249_3553400_-	ATP-dependent DNA helicase DinG	A0A127AW80	Bacillus_phage	3.7e-42	26.1
WP_001145128.1\|3553519_3554002_+	N-glycosidase YbiA	A0A0H3TLU0	Faustovirus	1.5e-36	52.7
3554083:3554117	attL	NA	NA	NA	NA
WP_000007101.1\|3554233_3555598_-	ATP-dependent RNA helicase RhlE	A0A1V0SBR7	Catovirus	1.5e-52	31.8
WP_001296991.1\|3555826_3556498_+	DNA-binding transcriptional regulator CecR	NA	NA	NA	NA
WP_001296990.1\|3556500_3557496_+	secretion protein HlyD	NA	NA	NA	NA
WP_000996091.1\|3557488_3559225_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.3e-18	30.3
WP_000070131.1\|3559217_3560351_+	ABC transporter permease	NA	NA	NA	NA
WP_000469031.1\|3560361_3561468_+	ABC transporter permease	NA	NA	NA	NA
WP_000871982.1\|3561429_3561840_-	YbhQ family protein	NA	NA	NA	NA
WP_001113348.1\|3561972_3562734_+	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_000650337.1\|3562730_3563972_+	cardiolipin synthase ClsB	NA	NA	NA	NA
WP_000045450.1\|3563971_3564928_+	UPF0104 family protein	NA	NA	NA	NA
WP_001088647.1\|3564963_3565677_-	Bax inhibitor-1/YccA family protein	NA	NA	NA	NA
WP_001331162.1\|3565746_3566394_-	Bax inhibitor-1 family protein	NA	NA	NA	NA
WP_000373624.1\|3566595_3567300_-	Bax inhibitor-1/YccA family protein	NA	NA	NA	NA
WP_000852287.1\|3567436_3567889_-	molybdopterin synthase catalytic subunit MoaE	NA	NA	NA	NA
WP_000598616.1\|3567890_3568136_-	molybdopterin synthase sulfur carrier subunit	NA	NA	NA	NA
WP_000080885.1\|3568128_3568614_-	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_000084632.1\|3568616_3569129_-	molybdenum cofactor biosynthesis protein B	NA	NA	NA	NA
WP_001295301.1\|3569150_3570140_-	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
WP_001295302.1\|3570536_3571445_+	uridine diphosphate-N-acetylglucosamine-binding protein YvcK	A1IMD5	Streptococcus_phage	1.4e-27	31.1
WP_000042533.1\|3571636_3573658_-	excinuclease ABC subunit B	NA	NA	NA	NA
WP_000044868.1\|3574236_3574914_-	ATP-dependent dethiobiotin synthetase BioD	NA	NA	NA	NA
WP_000246805.1\|3574906_3575662_-	malonyl-ACP O-methyltransferase BioC	NA	NA	NA	NA
WP_000118840.1\|3575648_3576803_-	8-amino-7-oxononanoate synthase	NA	NA	NA	NA
WP_000951213.1\|3576799_3577840_-	biotin synthase BioB	NA	NA	NA	NA
WP_001307065.1\|3577926_3579216_+	adenosylmethionine--8-amino-7-oxononanoate transaminase	A0A1V0SKB7	Klosneuvirus	1.0e-18	29.0
WP_000767389.1\|3579274_3579751_+	kinase inhibitor	NA	NA	NA	NA
WP_000586343.1\|3580496_3581828_+	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	2.5e-20	37.1
WP_000885623.1\|3581901_3582486_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	9.2e-105	95.4
WP_001387657.1\|3582485_3585560_-\|tail	prophage tail fiber N-terminal domain-containing protein	U5N099	Enterobacteria_phage	2.5e-68	82.1
WP_001233090.1\|3585624_3586224_-	Ail/Lom family protein	A5LH44	Enterobacteria_phage	8.2e-109	97.5
WP_000515639.1\|3586294_3589792_-	host specificity protein J	A0A291AWT4	Escherichia_phage	0.0e+00	97.6
WP_000090917.1\|3589852_3590485_-\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	5.9e-97	100.0
WP_000140717.1\|3590421_3591165_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	2.1e-146	96.8
WP_001152576.1\|3591170_3591869_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	4.7e-132	98.3
WP_000847391.1\|3591868_3592198_-\|tail	phage tail protein	A0A2R9YJM0	Escherichia_phage	8.7e-52	90.8
WP_014966180.1\|3592194_3594756_-\|tail	phage tail tape measure protein	A0A0K2FI43	Enterobacteria_phage	0.0e+00	97.7
WP_000459457.1\|3594748_3595183_-\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
WP_000479200.1\|3595164_3595587_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	1.4e-59	85.0
WP_001390429.1\|3595602_3596343_-\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	6.8e-129	97.2
WP_000683129.1\|3596350_3596746_-\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	8.5e-70	98.5
WP_000975081.1\|3596742_3597321_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.9e-80	99.5
WP_000785282.1\|3597332_3597686_-\|head,tail	head-tail joining protein	A0A2R9YJJ5	Escherichia_phage	6.4e-61	97.4
WP_000158875.1\|3597697_3598093_-	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	1.1e-58	95.5
WP_000063238.1\|3598134_3599160_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	4.7e-189	97.9
WP_001299443.1\|3599215_3599548_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	1.7e-55	100.0
WP_000123216.1\|3599557_3600877_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.4e-230	97.7
WP_001316944.1\|3600857_3602459_-\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	1.2e-311	99.8
WP_000198149.1\|3602455_3602662_-	gpW family protein	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_000453580.1\|3604557_3605103_-	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	2.8e-95	100.0
WP_000105084.1\|3605491_3605725_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	7.3e-21	94.4
WP_000079508.1\|3605781_3606192_+	DUF1398 family protein	C6ZCX4	Enterobacteria_phage	1.3e-52	76.3
WP_001028465.1\|3606541_3607063_-	KilA-N domain-containing protein	K7P7K9	Enterobacteria_phage	1.5e-93	100.0
WP_000092234.1\|3607267_3607705_-\|lysis	lysis protein	K7P710	Enterobacteria_phage	3.0e-68	94.5
WP_001135297.1\|3607701_3608199_-	lysozyme RrrD	M1FJA0	Enterobacteria_phage	3.2e-90	97.6
WP_000839596.1\|3608198_3608414_-\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	9.0e-34	100.0
WP_000737263.1\|3609002_3610085_+	porin OmpD	Q1MVN1	Enterobacteria_phage	4.4e-161	78.7
WP_001204791.1\|3610273_3610657_-	antitermination protein QuuD	A0A088CD47	Shigella_phage	4.4e-55	83.3
WP_000971074.1\|3610742_3610883_-	YlcG family protein	K7PHH3	Enterobacteria_phage	6.5e-09	69.8
WP_000774504.1\|3611237_3611528_-	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	2.8e-46	92.7
WP_000224912.1\|3611520_3611691_-	hypothetical protein	K7P7K0	Enterobacteria_phage	1.4e-13	69.8
WP_001053034.1\|3611690_3612146_-	DNA base-flipping protein YbcN	I6PD71	Cronobacter_phage	4.9e-61	67.5
WP_072147432.1\|3612142_3612244_-	hypothetical protein	NA	NA	NA	NA
WP_001391403.1\|3612340_3612592_-	hypothetical protein	NA	NA	NA	NA
WP_000338663.1\|3613168_3613408_-	hypothetical protein	NA	NA	NA	NA
WP_000145901.1\|3614559_3614862_-	protein ren	M1FPD5	Enterobacteria_phage	6.1e-44	97.8
WP_000788812.1\|3614858_3615560_-	hypothetical protein	M1FJ72	Enterobacteria_phage	1.4e-128	98.7
WP_000147903.1\|3615556_3616576_-	replication protein	A0A0M5M7Y1	Salmonella_phage	9.7e-110	63.4
WP_001182903.1\|3616572_3617112_-	toxin YdaT domain-containing protein	M9NZI6	Enterobacteria_phage	1.2e-61	66.1
WP_001067458.1\|3617181_3617412_-	helix-turn-helix domain-containing protein	A0A2H4FNF3	Salmonella_phage	1.5e-21	68.0
WP_000858975.1\|3617517_3618207_+	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	2.8e-92	75.0
WP_000233576.1\|3618804_3619011_+	phage encoded cell division inhibitor protein	K7P6H3	Enterobacteria_phage	3.2e-28	85.3
WP_000995433.1\|3619086_3619383_+	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	6.2e-49	99.0
WP_000100847.1\|3619388_3620174_+	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
WP_000186833.1\|3620170_3620851_+	YqaJ viral recombinase family protein	B6DZ61	Enterobacteria_phage	5.1e-131	98.2
WP_000682318.1\|3620847_3621030_+	DUF1317 domain-containing protein	A0A0N7CHV0	Escherichia_phage	1.3e-28	98.3
WP_000548541.1\|3621002_3621194_+	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	4.7e-26	98.4
WP_000188870.1\|3621270_3621486_+	hypothetical protein	A0A1I9LJM7	Stx_converting_phage	1.0e-32	100.0
WP_000763367.1\|3621584_3621806_+	TraR/DksA family transcriptional regulator	A0A0K2FI84	Escherichia_phage	2.9e-35	100.0
WP_000120064.1\|3622016_3622619_-	hypothetical protein	NA	NA	NA	NA
WP_000545745.1\|3622861_3623029_+	hypothetical protein	A5VWB7	Enterobacteria_phage	2.9e-27	98.2
WP_001303849.1\|3623068_3623287_+	excisionase	Q77WA4	Escherichia_phage	3.7e-35	100.0
WP_000533642.1\|3623264_3624335_+\|integrase	tyrosine-type recombinase/integrase	Q9MCR4	Enterobacteria_phage	5.1e-202	100.0
3625769:3625803	attR	NA	NA	NA	NA

DBSCAN-SWA_12

4142577 : 4198882

Enterobacteria_phage(27.27%)

integrase,plate

attL 4143958:4143977|attR 4156918:4156937

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000772650.1\|4142577_4143792_-\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	8.8e-134	56.7
4143958:4143977	attL	NA	NA	NA	NA
WP_001269640.1\|4144119_4145397_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_001240678.1\|4145477_4146155_-	hypothetical protein	A0A1D7XFF4	Escherichia_phage	8.6e-46	51.8
WP_000891726.1\|4146202_4148044_-	hypothetical protein	A0A140G5Z0	Enterobacteria_phage	1.9e-18	27.5
WP_001387927.1\|4148078_4148276_-	hypothetical protein	NA	NA	NA	NA
WP_000999102.1\|4148427_4149459_-	hypothetical protein	NA	NA	NA	NA
WP_000013184.1\|4149473_4149857_-	hypothetical protein	NA	NA	NA	NA
WP_000807036.1\|4149861_4150059_-	hypothetical protein	NA	NA	NA	NA
WP_000390662.1\|4151049_4151349_-	hypothetical protein	NA	NA	NA	NA
WP_000580786.1\|4151348_4151552_-	hypothetical protein	NA	NA	NA	NA
WP_000532776.1\|4151609_4151993_-	hypothetical protein	NA	NA	NA	NA
WP_000221926.1\|4152090_4152360_-	hypothetical protein	NA	NA	NA	NA
WP_000594462.1\|4152369_4153038_-	hypothetical protein	NA	NA	NA	NA
WP_001296967.1\|4153185_4153368_-	hypothetical protein	NA	NA	NA	NA
WP_001273869.1\|4155042_4155594_+	recombinase family protein	Q2A092	Sodalis_phage	3.2e-30	43.9
WP_000550450.1\|4155934_4156093_+	hypothetical protein	NA	NA	NA	NA
WP_000788776.1\|4156159_4156312_-	hypothetical protein	NA	NA	NA	NA
WP_000893256.1\|4157108_4158362_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.3e-95	47.0
4156918:4156937	attR	NA	NA	NA	NA
WP_001285288.1\|4158373_4159477_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-61	40.4
WP_000749877.1\|4159764_4160820_+	phosphoporin PhoE	Q1MVN1	Enterobacteria_phage	2.2e-117	60.6
WP_000174677.1\|4160858_4161260_-	sigma factor-binding protein Crl	NA	NA	NA	NA
WP_000189541.1\|4161317_4162562_-	esterase FrsA	NA	NA	NA	NA
WP_001291990.1\|4162653_4163112_-	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_001293014.1\|4163372_4164830_+	cytosol nonspecific dipeptidase	NA	NA	NA	NA
WP_000602103.1\|4164886_4165501_-	peptide chain release factor H	NA	NA	NA	NA
WP_000528869.1\|4165497_4166637_-	RNA ligase RtcB family protein	A0A222ZMP7	Mycobacterium_phage	2.0e-31	31.7
WP_001059855.1\|4166882_4167335_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001226164.1\|4167331_4168387_-	DNA polymerase IV	NA	NA	NA	NA
WP_000207574.1\|4168457_4169243_-	putative lateral flagellar export/assembly protein LafU	NA	NA	NA	NA
WP_001386594.1\|4169187_4170927_+	flagellar type III secretion system protein FlhA	NA	NA	NA	NA
WP_000598758.1\|4171031_4171310_+	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_001030484.1\|4171302_4171659_+	type II toxin-antitoxin system HicB family antitoxin	NA	NA	NA	NA
WP_000543895.1\|4171715_4172489_-	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	1.2e-19	37.7
WP_000729704.1\|4172674_4172935_+	type II toxin-antitoxin system antitoxin DinJ	NA	NA	NA	NA
WP_000615974.1\|4172937_4173216_+	type II toxin-antitoxin system mRNA interferase toxin YafQ	NA	NA	NA	NA
WP_001225679.1\|4173371_4174112_+	murein L,D-transpeptidase	NA	NA	NA	NA
WP_000333380.1\|4174082_4174850_-	class II glutamine amidotransferase	NA	NA	NA	NA
WP_000284050.1\|4175055_4175634_-	D-sedoheptulose 7-phosphate isomerase	A0A067XQR2	Caulobacter_phage	1.1e-14	32.0
WP_000973081.1\|4175873_4178318_+	acyl-CoA dehydrogenase FadE	NA	NA	NA	NA
WP_000532698.1\|4178360_4178834_-	C-lysozyme inhibitor	NA	NA	NA	NA
WP_001118029.1\|4178987_4179758_+	2-oxoglutaramate amidase	NA	NA	NA	NA
WP_122985282.1\|4182245_4182431_+	hypothetical protein	NA	NA	NA	NA
WP_000939262.1\|4182345_4182828_-	hypothetical protein	NA	NA	NA	NA
WP_000103304.1\|4186550_4188692_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	3.7e-26	25.8
WP_001142958.1\|4188901_4189420_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_000037389.1\|4190116_4190617_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_000123970.1\|4190651_4190876_+	hypothetical protein	NA	NA	NA	NA
WP_000056978.1\|4190926_4192402_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_000611748.1\|4192408_4192822_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_000393853.1\|4192825_4194676_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_000348793.1\|4194639_4195722_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_001113725.1\|4195746_4197027_+	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_001080149.1\|4197023_4197548_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_000246421.1\|4197550_4198882_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA

DBSCAN-SWA_13

4515547 : 4579544

Stx2-converting_phage(33.33%)

transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000181142.1\|4515547_4516504_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	2.7e-61	52.5
WP_001137018.1\|4516970_4518203_+	multidrug efflux MFS transporter MdtM	NA	NA	NA	NA
WP_001037377.1\|4518243_4519524_+	DUF445 domain-containing protein	NA	NA	NA	NA
WP_001298930.1\|4519639_4520791_+	2-hydroxyacyl-CoA dehydratase subunit D	NA	NA	NA	NA
WP_000222495.1\|4520800_4521568_+	hypothetical protein	NA	NA	NA	NA
WP_000657676.1\|4521564_4521822_+	DUF3343 domain-containing protein	NA	NA	NA	NA
WP_001298932.1\|4521886_4522747_+	YjiK family protein	NA	NA	NA	NA
WP_001141192.1\|4522814_4523993_+	MFS transporter	NA	NA	NA	NA
WP_001151854.1\|4524005_4524560_-	RNA 2'-phosphotransferase	A0A2R2ZGT8	Clostridioides_phage	2.7e-37	45.6
WP_001295597.1\|4524809_4525493_+	nucleoside recognition pore and gate family inner membrane transporter	NA	NA	NA	NA
WP_000211971.1\|4525489_4525951_+	YjiG family protein	NA	NA	NA	NA
WP_000568407.1\|4525963_4527136_+	beta-aspartyl-peptidase	NA	NA	NA	NA
WP_000340758.1\|4527200_4528112_+	hypochlorite stress DNA-binding transcriptional regulator HypT	NA	NA	NA	NA
WP_000986215.1\|4528104_4528497_-	anti-adapter protein IraD	NA	NA	NA	NA
WP_120795393.1\|4528493_4528577_-	iraD leader peptide IdlP	NA	NA	NA	NA
WP_000062571.1\|4529168_4529999_+	DUF2686 family protein	NA	NA	NA	NA
WP_000833686.1\|4530139_4530913_-	Uxu operon transcriptional regulator	NA	NA	NA	NA
WP_000208220.1\|4531127_4532588_-	fructuronate reductase	H8ZJP8	Ostreococcus_tauri_virus	3.6e-49	31.9
WP_000438591.1\|4532668_4533853_-	mannonate dehydratase	NA	NA	NA	NA
WP_000558251.1\|4534192_4535536_+	gluconate permease GntP	NA	NA	NA	NA
WP_000250224.1\|4536642_4537320_-	hypothetical protein	NA	NA	NA	NA
WP_001329788.1\|4538151_4538349_-	hypothetical protein	NA	NA	NA	NA
WP_000813456.1\|4538520_4539123_-	hypothetical protein	NA	NA	NA	NA
WP_000235221.1\|4539217_4539424_-	AlpA family transcriptional regulator	NA	NA	NA	NA
WP_000840367.1\|4539564_4539831_+	hypothetical protein	NA	NA	NA	NA
WP_000221544.1\|4541048_4541618_+	inovirus Gp2 family protein	NA	NA	NA	NA
WP_000270971.1\|4541877_4542279_+	hypothetical protein	NA	NA	NA	NA
WP_001221614.1\|4542266_4542701_+	zinc-ribbon domain-containing protein	NA	NA	NA	NA
WP_001390365.1\|4543055_4543436_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	3.9e-64	98.4
WP_000612591.1\|4543432_4543780_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_014966184.1\|4543829_4545215_+\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	2.9e-258	89.3
WP_000823241.1\|4545453_4546812_-	esterase-like activity of phytase family protein	NA	NA	NA	NA
WP_000555341.1\|4547562_4547820_-	hypothetical protein	NA	NA	NA	NA
WP_001283626.1\|4548737_4549259_+	RNA polymerase sigma factor FecI	NA	NA	NA	NA
WP_001068910.1\|4549255_4550209_+	fec operon regulator FecR	NA	NA	NA	NA
WP_000188245.1\|4550295_4552620_+	Fe(3+) dicitrate transport protein FecA	NA	NA	NA	NA
WP_000879153.1\|4552664_4553567_+	Fe(3+) dicitrate ABC transporter substrate-binding protein FecB	NA	NA	NA	NA
WP_000125175.1\|4553563_4554562_+	iron-dicitrate ABC transporter permease FecC	NA	NA	NA	NA
WP_000684856.1\|4554558_4555515_+	Fe(3+) dicitrate ABC transporter permease subunit FecD	A0A2H4IY97	uncultured_Caudovirales_phage	1.1e-17	26.1
WP_000175457.1\|4555515_4556283_+	Fe(3+) dicitrate ABC transporter ATP-binding protein FecE	G3M9Y6	Bacillus_virus	6.4e-13	24.8
WP_000177057.1\|4556840_4557098_-	hypothetical protein	NA	NA	NA	NA
WP_001189126.1\|4557748_4559257_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	6.2e-44	31.8
WP_160371899.1\|4560832_4561675_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_001388979.1\|4561677_4562766_+	putative hexosyltransferase CapU	NA	NA	NA	NA
WP_001387303.1\|4562770_4563721_+	virulence factor VirK	NA	NA	NA	NA
WP_001390363.1\|4563785_4564730_+	lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase	NA	NA	NA	NA
WP_000088357.1\|4564910_4566050_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.5e-68	45.1
WP_001293435.1\|4566203_4568201_+\|holin	choline BCCT transporter BetT	A0A2I7QNT1	Vibrio_phage	7.4e-21	25.9
WP_000625669.1\|4568263_4569541_+	DUF2254 domain-containing protein	NA	NA	NA	NA
WP_000145474.1\|4569786_4570443_+	TetR family transcriptional regulator C-terminal domain-containing protein	NA	NA	NA	NA
WP_001422798.1\|4570623_4570752_-	alcohol dehydrogenase	NA	NA	NA	NA
WP_000422741.1\|4570890_4571316_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_000624722.1\|4571312_4571663_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_000080200.1\|4571693_4573307_+\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	1.8e-182	63.6
WP_001295538.1\|4574490_4575273_-	DeoR family transcriptional regulator	NA	NA	NA	NA
WP_000350265.1\|4575578_4576499_+	ribokinase	NA	NA	NA	NA
WP_000998350.1\|4576526_4577843_+	L-fucose:H+ symporter permease	NA	NA	NA	NA
WP_000107474.1\|4577854_4578868_+	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_001327567.1\|4579289_4579544_+\|transposase	transposase	Q6H9S5	Enterobacteria_phage	8.0e-21	62.2

DBSCAN-SWA_14

4637975 : 4696519

Klosneuvirus(11.11%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001162171.1\|4637975_4639328_-\|protease	metalloprotease PmbA	NA	NA	NA	NA
WP_000166270.1\|4639421_4639973_+	ribosome-associated protein	NA	NA	NA	NA
WP_001219816.1\|4640123_4641497_-	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase	NA	NA	NA	NA
WP_000853753.1\|4641672_4642671_+	class 1 fructose-bisphosphatase	A0A1V0SKX4	Klosneuvirus	5.7e-70	42.7
WP_000595979.1\|4642703_4643699_-	sugar ABC transporter permease YjfF	NA	NA	NA	NA
WP_001387274.1\|4643685_4644708_-	ABC transporter permease	NA	NA	NA	NA
WP_000205794.1\|4644721_4646224_-	sugar ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	1.1e-11	30.3
WP_000265933.1\|4646533_4647490_-	galactofuranose ABC transporter substrate-binding protein YtfQ	NA	NA	NA	NA
WP_000055072.1\|4647799_4648330_+	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	9.4e-56	63.9
WP_000239579.1\|4648409_4648760_-	endoribonuclease toxin ChpB	NA	NA	NA	NA
WP_001223208.1\|4648753_4649005_-	type II toxin-antitoxin system antitoxin ChpS	NA	NA	NA	NA
WP_001219160.1\|4649216_4649558_-	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_000060946.1\|4649560_4653340_-	autotransporter assembly complex protein TamB	NA	NA	NA	NA
WP_001269327.1\|4653336_4655070_-	autotransporter assembly complex protein TamA	NA	NA	NA	NA
WP_001295196.1\|4655275_4655914_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_000935042.1\|4656236_4657580_+	HlyC/CorC family transporter	NA	NA	NA	NA
WP_000689228.1\|4657641_4657848_-	DUF1107 domain-containing protein	NA	NA	NA	NA
WP_000175289.1\|4658172_4658730_+	YtfJ family protein	NA	NA	NA	NA
WP_000886909.1\|4658719_4659460_-	3'(2'),5'-bisphosphate nucleotidase CysQ	NA	NA	NA	NA
WP_000589423.1\|4659649_4661593_+	2',3'-cyclic-nucleotide 2'-phosphodiesterase	NA	NA	NA	NA
WP_000084622.1\|4661721_4662102_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000560563.1\|4662190_4663051_+	NAD(P)H:quinone oxidoreductase	NA	NA	NA	NA
WP_001296686.1\|4663158_4664124_+	DMT family transporter	NA	NA	NA	NA
WP_000331456.1\|4664231_4664894_+	iron-sulfur cluster repair protein YtfE	NA	NA	NA	NA
WP_000228346.1\|4664938_4666351_-	D-serine/D-alanine/glycine transporter	NA	NA	NA	NA
WP_000211225.1\|4666659_4667280_-	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_001119478.1\|4667498_4668137_+	cell division protein YtfB	NA	NA	NA	NA
WP_000826425.1\|4668271_4669480_-\|transposase	transposase	A0A077SL42	Escherichia_phage	9.2e-208	93.0
WP_000604912.1\|4669487_4669919_+\|transposase	IS200/IS605-like element IS609 family transposase	A0A1S5RHE3	Helicobacter_phage	1.9e-43	60.6
WP_001351393.1\|4670541_4671336_+	DUF2686 family protein	NA	NA	NA	NA
WP_001196062.1\|4671406_4671856_-	50S ribosomal protein L9	NA	NA	NA	NA
WP_000135199.1\|4671897_4672125_-	30S ribosomal protein S18	NA	NA	NA	NA
WP_001296681.1\|4672129_4672444_-	primosomal replication protein N	NA	NA	NA	NA
WP_001216676.1\|4672450_4672846_-	30S ribosomal protein S6	NA	NA	NA	NA
WP_000492914.1\|4673172_4673448_+	DUF1471 domain-containing protein	NA	NA	NA	NA
WP_000996728.1\|4673522_4674074_-	DUF1440 domain-containing protein	NA	NA	NA	NA
WP_001170812.1\|4674170_4674857_-	L-ribulose-5-phosphate 4-epimerase UlaF	NA	NA	NA	NA
WP_000949539.1\|4674856_4675711_-	L-ribulose-5-phosphate 3-epimerase UlaE	NA	NA	NA	NA
WP_000056760.1\|4675720_4676371_-	3-keto-L-gulonate-6-phosphate decarboxylase UlaD	NA	NA	NA	NA
WP_000776505.1\|4676384_4676849_-	PTS ascorbate transporter subunit IIA	NA	NA	NA	NA
WP_000218362.1\|4676858_4677164_-	PTS ascorbate transporter subunit IIB	NA	NA	NA	NA
WP_001300695.1\|4677179_4678577_-	PTS ascorbate transporter subunit IIC	NA	NA	NA	NA
WP_001295191.1\|4678931_4679996_+	L-ascorbate 6-phosphate lactonase	NA	NA	NA	NA
WP_000133631.1\|4680103_4680859_+	HTH-type transcriptional regulator UlaR	NA	NA	NA	NA
WP_000569708.1\|4680855_4681605_-	esterase	NA	NA	NA	NA
WP_000254636.1\|4681786_4682116_+	biofilm peroxide resistance protein BsmA	NA	NA	NA	NA
WP_000811566.1\|4682264_4682540_+\|protease	protease activator YjfN	NA	NA	NA	NA
WP_001339483.1\|4682656_4684282_-	isovaleryl-CoA dehydrogenase	NA	NA	NA	NA
WP_000943976.1\|4684365_4685529_-	glutathionylspermidine synthase family protein	B2ZXR7	Ralstonia_phage	1.3e-81	43.5
WP_000101644.1\|4685531_4686170_-	DUF1190 domain-containing protein	NA	NA	NA	NA
WP_000012553.1\|4686595_4687255_-	YjfK family protein	NA	NA	NA	NA
WP_000511955.1\|4687305_4688004_-	PspA/IM30 family protein	NA	NA	NA	NA
WP_000220137.1\|4688022_4688424_-	DUF2170 family protein	NA	NA	NA	NA
WP_001293282.1\|4688550_4689282_-	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_000076316.1\|4689461_4691903_-	ribonuclease R	Q0GXV6	Lactococcus_phage	6.4e-67	33.1
WP_001177639.1\|4691941_4692367_-	nitric oxide-sensing transcriptional repressor NsrR	NA	NA	NA	NA
WP_000527955.1\|4692571_4693870_-	adenylosuccinate synthase	W5S5V7	Pithovirus	2.2e-66	35.9
WP_001089295.1\|4693973_4694171_-	DUF2065 domain-containing protein	NA	NA	NA	NA
WP_001232412.1\|4694252_4695257_-\|protease	protease modulator HflC	NA	NA	NA	NA
WP_000312490.1\|4695259_4696519_-\|protease	FtsH protease activity modulator HflK	A0A1L2CVV0	Pectobacterium_phage	3.6e-05	25.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_018659

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

45167 : 55465

Salmonella_phage(22.22%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000239590.1\|45167_46043_-	class A extended-spectrum beta-lactamase CTX-M-15	A0A1B0VBP7	Salmonella_phage	1.1e-125	82.4
WP_000608644.1\|46298_47561_-\|transposase	IS1380-like element ISEc9 family transposase	A0A1B0VDR3	Salmonella_phage	1.3e-39	100.0
WP_001235713.1\|48124_48682_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
WP_000027057.1\|48864_49725_+	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_001245884.1\|49993_50296_-	hypothetical protein	NA	NA	NA	NA
WP_000587689.1\|50292_50919_-	ParA family plasmid-partitioning AAA ATPase	E5FFJ3	Burkholderia_phage	2.0e-17	31.1
WP_000457515.1\|51122_52394_-	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	2.2e-143	60.4
WP_000109071.1\|52393_52831_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	8.3e-26	48.4
WP_000618110.1\|52827_53076_-	DinI-like family protein	Q2A098	Sodalis_phage	1.9e-14	48.0
WP_023383827.1\|53494_54397_+	DUF1281 domain-containing protein	NA	NA	NA	NA
WP_001310011.1\|54393_54705_+	hypothetical protein	NA	NA	NA	NA
WP_000086153.1\|54781_55465_+	DNA methylase	A0A2I7RE86	Vibrio_phage	5.1e-30	37.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_018666

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_018658

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NC_018659

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection