CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_018870	Thermacetogenium phaeum DSM 12270, complete sequence	12 crisprs	c2c9_V-U4,Cas14b_CAS-V-F,cas3,RT,csa3,cas4,cas2,cas1,csc1gr5,csc2gr7,cas11d,cas10d,cas3HD,WYL,cas6,cas5,cas7,cas8b1,csx1,csm3gr7,csm2gr11,csx10gr5,cas10,csx15,DinG	0	24	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_018870_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018870_1

1072199-1072754

Orphan

Consensus_repeat	Method
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA	PILER-CR
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAAAT	CRISPRCasFinder
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA	CRT

7 spacers

The CRISPR arrays of NC_018870_1

>merge|NC_018870|1|1072199-1072754|PILER-CR,CRISPRCasFinder,CRT
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAATTAATTGTGGTGAACAAGCATGGGAGCTGAGGGTGAAAAGGTTGCACTCATAACCCCGATGAAAAGGGGACTGAATTTGTCGTTCCGTTCCAGTAAAATGAGTCAAATCCAACGTTGCACTCATAACCCCGATGAAAAGGGGACTGAATTTCGATCTGTGTCTGCAACTCATCAAACAGCTTTTGCTCGTTGCACTCATAACCCCGATGAAAAGGGGACTGAAATCTGGGCAACGAACCGTTGAAGATTTACGTTCAACTCCTGTTGCACTCATAACCCCGATGAAAAGGGGACTGAAATTTGCCGACAAAAAAGCGAAAGGGAAGCTGACGTTGGAAGTTGCACTCATAACCCCGATGAAAAGGGGACTGAAATCTCGTCATCCACCGCACCGAAAAGACGACATATCAAGTTGCACTCATAACCCCGATGAAAAGGGGACTGAAATGTTATCTACGCCGTGCTCTTTGAGTATTTCCACGAAGTTGCACTCATAACCCCGATGAAAAGGGGACTGAAAG

>NC_018870|1|1|1072199-1072752|PILER-CR
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA	TTAATTGTGGTGAACAAGCATGGGAGCTGAGGGTGAAAAG
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA	TTTGTCGTTCCGTTCCAGTAAAATGAGTCAAATCCAAC
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA	TTTCGATCTGTGTCTGCAACTCATCAAACAGCTTTTGCTC
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA	ATCTGGGCAACGAACCGTTGAAGATTTACGTTCAACTCCT
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA	ATTTGCCGACAAAAAAGCGAAAGGGAAGCTGACGTTGGAA
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA	ATCTCGTCATCCACCGCACCGAAAAGACGACATATCAA
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA	ATGTTATCTACGCCGTGCTCTTTGAGTATTTCCACGAA
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA

>NC_018870|1|1|1072199-1072754|CRISPRCasFinder
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAATT	AATTGTGGTGAACAAGCATGGGAGCTGAGGGTGAAAAG
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAATT	TGTCGTTCCGTTCCAGTAAAATGAGTCAAATCCAAC
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAATT	TCGATCTGTGTCTGCAACTCATCAAACAGCTTTTGCTC
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAAAT	CTGGGCAACGAACCGTTGAAGATTTACGTTCAACTCCT
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAAAT	TTGCCGACAAAAAAGCGAAAGGGAAGCTGACGTTGGAA
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAAAT	CTCGTCATCCACCGCACCGAAAAGACGACATATCAA
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAAAT	GTTATCTACGCCGTGCTCTTTGAGTATTTCCACGAA
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAAAG

>NC_018870|1|1|1072199-1072752|CRT
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA	TTAATTGTGGTGAACAAGCATGGGAGCTGAGGGTGAAAAG
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA	TTTGTCGTTCCGTTCCAGTAAAATGAGTCAAATCCAAC
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA	TTTCGATCTGTGTCTGCAACTCATCAAACAGCTTTTGCTC
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA	ATCTGGGCAACGAACCGTTGAAGATTTACGTTCAACTCCT
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA	ATTTGCCGACAAAAAAGCGAAAGGGAAGCTGACGTTGGAA
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA	ATCTCGTCATCCACCGCACCGAAAAGACGACATATCAA
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA	ATGTTATCTACGCCGTGCTCTTTGAGTATTTCCACGAA
GTTGCACTCATAACCCCGATGAAAAGGGGACTGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_018870.1\|WP_148275852.1\|1079768_1080146_-\|gas-vesicle-protein	unknown	unknown	gnl\|CDD\|376379
NC_018870.1\|WP_015050141.1\|1066486_1067089_+\|DUF3786-domain-containing-protein	unknown	unknown	gnl\|CDD\|372241
NC_018870.1\|WP_081578604.1\|1077474_1077603_+\|cyclic-lactone-autoinducer-peptide	unknown	unknown	gnl\|CDD\|275064
NC_018870.1\|WP_028991050.1\|1080345_1080642_+\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015050142.1\|1067153_1067459_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|198134
NC_018870.1\|WP_148275851.1\|1071345_1071684_-\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015050151.1\|1076327_1076819_+\|DUF89-family-protein	unknown	unknown	gnl\|CDD\|224494
NC_018870.1\|WP_015050140.1\|1065102_1066347_+\|(Fe-S)-binding-protein	unknown	unknown	gnl\|CDD\|223325
NC_018870.1\|WP_015050147.1\|1070868_1071090_+\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015050143.1\|1067522_1068002_-\|bifunctional-nuclease-family-protein	unknown	unknown	gnl\|CDD\|376830
NC_018870.1\|WP_015050145.1\|1069749_1070220_-\|HAD-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|226572
NC_018870.1\|WP_015050148.1\|1073260_1074673_+\|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_018870.1\|WP_015050144.1\|1068044_1069583_-\|YifB-family-Mg-chelatase-like-AAA-ATPase	unknown	unknown	gnl\|CDD\|223679
NC_018870.1\|WP_015050154.1\|1078306_1079053_-\|GvpL/GvpF-family-gas-vesicle-protein	unknown	unknown	gnl\|CDD\|377652
NC_018870.1\|WP_015050155.1\|1079131_1079362_-\|gas-vesicle-structural-protein-GvpA	unknown	unknown	gnl\|CDD\|181805
NC_018870.1\|WP_155990786.1\|1070701_1070854_-\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015050139.1\|1063717_1065103_+\|FAD-binding-protein	unknown	unknown	gnl\|CDD\|273050
NC_018870.1\|WP_015050156.1\|1079482_1079794_-\|gas-vesicle-protein-K	unknown	unknown	gnl\|CDD\|377462
NC_018870.1\|WP_015050153.1\|1078045_1078282_-\|gas-vesicle-protein-GvpG	unknown	unknown	gnl\|CDD\|310007
NC_018870.1\|WP_015050150.1\|1075906_1076389_+\|DUF89-family-protein	unknown	unknown	gnl\|CDD\|224494

Protein	Function_ID	Function_description	E-value
NC_018870.1\|WP_148275852.1\|1079768_1080146_-\|gas-vesicle-protein	gnl\|CDD\|376379	pfam00741, Gas_vesicle, Gas vesicle protein.	9.87984e-14
NC_018870.1\|WP_015050141.1\|1066486_1067089_+\|DUF3786-domain-containing-protein	gnl\|CDD\|372241	pfam12654, DUF3786, Domain of unknown function (DUF3786). This presumed domain is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 201 and 257 amino acids in length. Some proteins also contains an iron-sulfur cluster.	7.34979e-64
NC_018870.1\|WP_081578604.1\|1077474_1077603_+\|cyclic-lactone-autoinducer-peptide	gnl\|CDD\|275064	TIGR04223, quorum_AgrD, cyclic lactone autoinducer peptide. Members of this family of short peptides are precursors to thiolactone (unless Cys is replaced by Ser) cyclic autoinducer peptides, used in quorum-sensing systems in Gram-positive bacteria. The best characterized is the AgrD precursor, processed by the AgrB protein. Nearby proteins regularly encountered include a histidine kinase and a response regulator. This model is related to pfam05931 but is newer and currently broader in scope.	1.43527e-08
NC_018870.1\|WP_015050139.1\|1063717_1065103_+\|FAD-binding-protein	gnl\|CDD\|273050	TIGR00387, Glycolate_oxidase_subunit_glcD., glycolate oxidase, subunit GlcD. This protein, the glycolate oxidase GlcD subunit, is similar in sequence to that of several D-lactate dehydrogenases, including that of E. coli. The glycolate oxidase has been found to have some D-lactate dehydrogenase activity. [Energy metabolism, Other].	0
NC_018870.1\|WP_015050151.1\|1076327_1076819_+\|DUF89-family-protein	gnl\|CDD\|224494	COG1578, COG1578, Uncharacterized conserved protein [Function unknown].	4.1396e-46
NC_018870.1\|WP_015050140.1\|1065102_1066347_+\|(Fe-S)-binding-protein	gnl\|CDD\|223325	COG0247, GlpC, Fe-S oxidoreductase [Energy production and conversion].	5.90676e-87
NC_018870.1\|WP_015050142.1\|1067153_1067459_+\|hypothetical-protein	gnl\|CDD\|198134	smart01066, CBM_25, Carbohydrate binding domain.	4.61604e-25
NC_018870.1\|WP_015050143.1\|1067522_1068002_-\|bifunctional-nuclease-family-protein	gnl\|CDD\|376830	pfam02577, DNase-RNase, Bifunctional nuclease. This family is a bifunctional nuclease, with both DNase and RNase activity. It forms a wedge-shaped dimer, with each monomer being triangular in shape. A large groove at the thick end of the wedge contains a possible active site.	2.20226e-55
NC_018870.1\|WP_015050145.1\|1069749_1070220_-\|HAD-hydrolase-family-protein	gnl\|CDD\|226572	COG4087, COG4087, Soluble P-type ATPase [General function prediction only].	1.31551e-24
NC_018870.1\|WP_015050148.1\|1073260_1074673_+\|group-II-intron-reverse-transcriptase/maturase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	0
NC_018870.1\|WP_015050144.1\|1068044_1069583_-\|YifB-family-Mg-chelatase-like-AAA-ATPase	gnl\|CDD\|223679	COG0606, COG0606, Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones].	0
NC_018870.1\|WP_015050154.1\|1078306_1079053_-\|GvpL/GvpF-family-gas-vesicle-protein	gnl\|CDD\|377652	pfam06386, GvpL_GvpF, Gas vesicle synthesis protein GvpL/GvpF. This family consists of several bacterial and archaeal gas vesicle synthesis protein (GvpL/GvpF) sequences. The exact function of this family is unknown.	7.42161e-74
NC_018870.1\|WP_015050155.1\|1079131_1079362_-\|gas-vesicle-structural-protein-GvpA	gnl\|CDD\|181805	PRK09371, PRK09371, gas vesicle structural protein GvpA.	4.354e-24
NC_018870.1\|WP_015050156.1\|1079482_1079794_-\|gas-vesicle-protein-K	gnl\|CDD\|377462	pfam05121, GvpK, Gas vesicle protein K. These proteins are involved in the formation of gas vesicles.	6.725e-14
NC_018870.1\|WP_015050153.1\|1078045_1078282_-\|gas-vesicle-protein-GvpG	gnl\|CDD\|310007	pfam05120, GvpG, Gas vesicle protein G. These proteins are involved in the formation of gas vesicles.	8.12869e-08
NC_018870.1\|WP_015050150.1\|1075906_1076389_+\|DUF89-family-protein	gnl\|CDD\|224494	COG1578, COG1578, Uncharacterized conserved protein [Function unknown].	3.70257e-19

>NC_018870.1|WP_148275851.1|1071345_1071684_-|hypothetical-protein
MTSTGSTSAGTSYVSDDRSVAAAERSVQCYVLSGAVGIGLQTPEPLEVGFIYLQRVGLNLDASTTGALTVTGTGALLPPKVTVISAFPLETPFDLAGFGDQCDGSAAGPVAG
>NC_018870.1|WP_015050147.1|1070868_1071090_+|hypothetical-protein
MHIVRDAEGVFNRQAPADQKREGIYEGKTASIPVTVTAPVLERISVSPEQMNIAAGKTGQLLRPSTRTEPRKT
>NC_018870.1|WP_155990786.1|1070701_1070854_-|hypothetical-protein
MDYYVVVFAAQIVVDEWGFGKAAITGGGRCPPGRSFLKLFLALRSSSSRL
>NC_018870.1|WP_015050145.1|1069749_1070220_-|HAD-hydrolase-family-protein
MLKINIPGKGDLSLQHLIVDYNGTIAFDGNLISGVAEQLNQLAEYLEIHILTADTFGTASQKCRELQANIKLITSKNGTLEKGRIVDSLGPKKVVAIGNGVNDTLMLKKAALGIAVIGKEGAAQIAISKADVIVNDIQDALGLLLNTTRLKATLRA
>NC_018870.1|WP_015050144.1|1068044_1069583_-|YifB-family-Mg-chelatase-like-AAA-ATPase
MLSIINSCCCLGMETHNVRVEVDVSPGLPCITIVGLPDPAVREATERVRSAIRNTGFEFPLKRVTVNLAPADLRKEGSLFDLPIAIGILAATEQLPFDKIPQHILVGELSLDGTIRRVPGVLLMAGSIHQNSPEKTLIIPLDNLSEAALVKGVPALGAGNLNEVAAFLKGERELPAAPEETGSQLLEDDDSTGYPDFADVKGQEKAKRALEIAAAGGHNILMVGPPGTGKTLLARSLPSILPPLSWEECLEVTKVYSIAGLLPKERPVISKRPFRAPHHTASAVSIIGGGRVPHPGEVSFATHGILFLDELPEFSRDVLEALRQPLEEGVVTISRAHGAYTFPARFIFVGAMNPCPCGHLGDPHKECTCTPYQAQRYRSRVSGPILDRIDLQIEVPRLELSELSSEKSAESSQEIRKRVVRAHKIQQERFRNTGVHCNAQMKSQHLKTFCQLKKESRDLLHQVFHNLKMSMRAHDRVLKIARTIADLEESVQIEPVHLAEAVQYRCLDRPFW
>NC_018870.1|WP_015050143.1|1067522_1068002_-|bifunctional-nuclease-family-protein
MIPVQVKEIAFDLSLSPVVLLVDESQKRALPISIGPFEAQSIAMALQGVITPRPMTHDLMKSFCDNLGASIRRVVINDIRDGTYYAEMYIQTVSGELVLDSRPSDAIALALRAGAPVYISEKLIDYTLSVDELMDESQQQELRKILGINNLDDFKKSLH
>NC_018870.1|WP_015050142.1|1067153_1067459_+|hypothetical-protein
MYNLHPGFTISPVPSKVGEKCKIRYHGLLATSGADQVWLRTGYGTGPWQNIYDYRMNKVGPNEWEQTVEITREGQFNFCFKDSANNWDNNNGLNWSYTIRR
>NC_018870.1|WP_015050141.1|1066486_1067089_+|DUF3786-domain-containing-protein
MFSAVYEEARCAFAARSPGEMADLSGAIYDSSEKTIHVAYFGRTYQVSHPEGTISSPYDPVELPLEEKALILQYLSQATGEPLSGRWIAYAELPNGMLHNQPFRVEAVEPLADTFGSRPEKLVEAAHYLGGWEIEIGDAAVVIPVFKRLYVAVVIWVADDEFPASANMVFDAAAPKYLSTAALYVLGSVVTKRIKNVVDL
>NC_018870.1|WP_015050140.1|1065102_1066347_+|(Fe-S)-binding-protein
MDKIVALKHLDRCSKCGSCQAVCPLYAETRMEPLVARGKLFLIRNYLEGELGITRRMKELMSLCLLCKACTAQCPNGIPVDRLVLGIRQEIAREKGISFVKKNVFQHLLQNNGRLTMAAKMAYLYQKSGLQWLARRSRILEFLGGNLARKEELLPQMASRPFRSQVPQHFPCNRPRLRVGYYTGCLTNYVFPATGHAVIDVLRRHQVEVVVPEQWCCGIPALASGDEEAAAKLAQKNVESFLKSGVDAVIVDCASCGSMLRYYVELLGTEEAQRFSEKVLDISQFLADAVSFQPGEREVPLVVTYHDPCHLRRGQGVAKAPRDLIKSLPGVIFREMKEADRCCGAAGSFNLAHYDLANRIGRRKVQNILQTGAQAVVTGCPSCIMQISHLLARENAPVKVMHIAELISRTYLKK
>NC_018870.1|WP_015050139.1|1063717_1065103_+|FAD-binding-protein
MIKEEVIKEIRKVVGDENVLVSKEDRLCYGYDSTPVAYLPDLVVRPSSTEEIRTIVELANRHLFPIIPRGAGTGLSGGSLPVEGGVVIDLTRMDRILEIDEENLIAVVEPGVVTYHLQQEVERRGLFYPPDPASLKTSTIGGNVAECAGGPRAFKYGVTRDYVLGLEVVTPTGQVIETGGKTVKSVTGYDLTRLYTGSEGTLGIITKIYLRLIPLPEAKKTLMAVYGKLDDAARSVTLIIKEGIIPVTLEIMDDRTIQCVENYRHLGLPLDAEAILIIEVDGPQVLIEEQAGRVAALCRDNGAREVKVAETEEEREQIWASRRAVSAAVVQIKPTKISEDISVPRSAIPEMVRRLKEIASRYRLDLVIFGHAGDGNLHPNILCDKNDPDEMERVEKAIGELFRAAVELGGTLSGEHGIGTMKAPYLKLETGEAGYQVMQSIKSALDPNNILNPGKIFRSDI
>NC_018870.1|WP_015050148.1|1073260_1074673_+|group-II-intron-reverse-transcriptase/maturase
MSSREGRRQQKTPGGACLREEVVKPRGTAGGPSSSPARGGAAPRGGQGSGLMEQVVERSNMLAALKRVERNGGAPGIDGVPTERLRDQIRAEWRRIREELLAGTYRPEPVRRVEIPKPGGGERLLGIPTVMDRLIQQALLQVLTPIFDPQFSDSSYGFRPGRRAHDAVKRARQYVEEGYEWAVDLDIEKFFDRVNHDILMARVARRVTDKRVLTLIRRYLQAGVMVNGVVMETAEGTPQGGPLSPLLANILLDDLDKELEKRGHKFVRYADDCNIYVKSKRAGERVMASVRNFLQERLKLKINEQKSAVDRPWKLKFLGFSMYKPKGGVILIRLASQTIDRVKAKIRGITARNKPISMDERIERLNTYLGGWIGYFALADTPSVFKDIEGWMRRRLRMCLWKQWKRVRTRYRELRALGLPEWVVHHFANARKGPWRMAHGPMNRALGNAYWQSHGLMSLTERYHRLRQAW
>NC_018870.1|WP_015050150.1|1075906_1076389_+|DUF89-family-protein
MKLSVNCIPCLINQAVTQAKFHLDDEEQQFALVEKVMKELLSAERRCAPCVAQKIQRVLRESLQNPDPYKAQKTFYNKEMLKLEEAFQKAVAAVSADPLEQGLRLAVAGNIIDFGPYHDLSPEKVLKVVQETVKKDYKKRDAYKIKGKIKQGPETSLSGG
>NC_018870.1|WP_015050151.1|1076327_1076819_+|DUF89-family-protein
MLIKLKEKLSKAQKLLYLGDNAGEIVFDKLFIKKIKDVYRNLDIFFATRGYPTLNDVTEEDAYAVGMDRCAKIVNNGTDIPGTILEACSSQFLKVFHEADFVIAKGQGNFESLYGECEKDICFIFLCKCSLFEERLGVRKHDIVLMFNRPLILTSKLQQTAPQ
>NC_018870.1|WP_081578604.1|1077474_1077603_+|cyclic-lactone-autoinducer-peptide
MFRTVKTNLLRFASVLLLVVAATGVSATCWFHWYQPKLPEKG
>NC_018870.1|WP_015050153.1|1078045_1078282_-|gas-vesicle-protein-GvpG
MIIDDLLLLPLRGLLAIAEKIDDAVRQELEDADYLRSKLLELQLSYELGDIEQEEYEESYRRLVERLQALERETEDNP
>NC_018870.1|WP_015050154.1|1078306_1079053_-|GvpL/GvpF-family-gas-vesicle-protein
MPSPKLYYAYGIVETPPSTPPDSLTGDSGRELIPITYKDITLIAGIISDFTYTPTPENARSHSQTVTRLGEQFNVIPLRFGTVFKEEEEAVQMLASRYQEIKRIFSQIRNRIELGLKVIWKKECLAAELESRYPELARIKEEIQALPPESAYHSAILLGQRVEEAVLELRSIYTPQILEPLEKTAVNTRLNKPLNERMVLNAAFLVEKEKELLFDEQVNALYERFRERFDFKYSGPWPPYNFVDLESD
>NC_018870.1|WP_015050155.1|1079131_1079362_-|gas-vesicle-structural-protein-GvpA
MAVTKSTDANSLVEVIDRILDKGLVIDAWIKVALVGIELLSVEARVVVAGVETYLKYAEAIGLTRLAAPPQAIAAA
>NC_018870.1|WP_015050156.1|1079482_1079794_-|gas-vesicle-protein-K
MPIQINEDNLKEGLLGLVVALVEIIKDLLELQALRRMESGNLGEEEIISLGEALMDLGEALERIKEENGITTTVRNIRLSLDDLVDDVLDRMLNPERWAEDAT
>NC_018870.1|WP_148275852.1|1079768_1080146_-|gas-vesicle-protein
MSWISDKEAYYDTEPLSIAWPVQTAFNPHERLLTDLNRCSTQSSGGGLTVDPTREGPGALADVLDRLLNKGLVLHLDLVIGVANIPLIGINLRAVVAAVETMIEYGFMEKDWVRGSKVANPDQRG
>NC_018870.1|WP_028991050.1|1080345_1080642_+|hypothetical-protein
MSSLVENMEELASEIISSFRNRRKNLHELQEEVKNLLRLFETERLEMRAGLQKELHDFINDLEVRVNKLLAEFEEERYRAEQIWMEMENKMEHLRRVK

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Crispr_ID: NC_018870_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018870_2

1421404-1421512

Orphan

Consensus_repeat	Method
GCATCATCGCCTGGTGATCCACGTGGTGGTTTGCAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_018870_2

>merge|NC_018870|2|1421404-1421512|CRISPRCasFinder
GCATCATCGCCTGGTGATCCACGTGGTGGTTTGCAACTTCTGTGGCGAAAAGTGAGGGGTCATTATCTTTTCGCATCATCGCCTGGTGATCCACGTGGTGGTTTGCAAC

>NC_018870|2|2|1421404-1421512|CRISPRCasFinder
GCATCATCGCCTGGTGATCCACGTGGTGGTTTGCAAC	TTCTGTGGCGAAAAGTGAGGGGTCATTATCTTTTC
GCATCATCGCCTGGTGATCCACGTGGTGGTTTGCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018870.1\|WP_028990990.1\|1428716_1429571_-\|LuxR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197715
NC_018870.1\|WP_015050488.1\|1413480_1414077_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226597
NC_018870.1\|WP_028990991.1\|1427063_1427267_+\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015050482.1\|1404150_1405878_-\|DNA-mismatch-repair-endonuclease-MutL	unknown	unknown	gnl\|CDD\|234630
NC_018870.1\|WP_081578627.1\|1405902_1407315_-\|histone-deacetylase	unknown	unknown	gnl\|CDD\|212518
NC_018870.1\|WP_015050492.1\|1422985_1423489_-\|6,7-dimethyl-8-ribityllumazine-synthase	unknown	unknown	gnl\|CDD\|234606
NC_018870.1\|WP_015050489.1\|1419656_1420568_+\|DUF4338-domain-containing-protein	unknown	unknown	gnl\|CDD\|372975
NC_018870.1\|WP_015050494.1\|1424742_1425393_-\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|236455
NC_018870.1\|WP_015050495.1\|1425374_1426523_-\|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	unknown	unknown	gnl\|CDD\|273015
NC_018870.1\|WP_028990989.1\|1431732_1432086_-\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_148275872.1\|1412029_1413358_-\|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	unknown	unknown	gnl\|CDD\|237675
NC_018870.1\|WP_015050481.1\|1403188_1404133_-\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	unknown	unknown	gnl\|CDD\|234626
NC_018870.1\|WP_015050493.1\|1423503_1424718_-\|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II	unknown	unknown	gnl\|CDD\|181774
NC_018870.1\|WP_037999028.1\|1408963_1411588_-\|DNA-mismatch-repair-protein-MutS	unknown	unknown	gnl\|CDD\|235444
NC_018870.1\|WP_015050484.1\|1407256_1408936_-\|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl\|CDD\|223223
NC_018870.1\|WP_015050491.1\|1422444_1423008_-\|phosphodiesterase	unknown	unknown	gnl\|CDD\|181869
NC_018870.1\|WP_015050490.1\|1422259_1422448_+\|50S-ribosomal-protein-L28	unknown	unknown	gnl\|CDD\|234736
NC_018870.1\|WP_015050480.1\|1402878_1403151_-\|RNA-chaperone-Hfq	unknown	unknown	gnl\|CDD\|379947
NC_018870.1\|WP_015050486.1\|1411628_1412000_-\|YlbF-family-regulator	unknown	unknown	gnl\|CDD\|377611
NC_018870.1\|WP_015050500.1\|1430877_1431291_-\|transposase	unknown	unknown	gnl\|CDD\|372705

Protein	Function_ID	Function_description	E-value
NC_018870.1\|WP_028990990.1\|1428716_1429571_-\|LuxR-family-transcriptional-regulator	gnl\|CDD\|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	2.04568e-17
NC_018870.1\|WP_015050488.1\|1413480_1414077_-\|hypothetical-protein	gnl\|CDD\|226597	COG4112, COG4112, Predicted phosphoesterase (MutT family) [General function prediction only].	4.68005e-42
NC_018870.1\|WP_015050482.1\|1404150_1405878_-\|DNA-mismatch-repair-endonuclease-MutL	gnl\|CDD\|234630	PRK00095, mutL, DNA mismatch repair endonuclease MutL.	0
NC_018870.1\|WP_081578627.1\|1405902_1407315_-\|histone-deacetylase	gnl\|CDD\|212518	cd09992, HDAC_classII, Histone deacetylases and histone-like deacetylases, classII. Class II histone deacetylases are Zn-dependent enzymes that catalyze hydrolysis of N(6)-acetyl-lysine residues of histones (EC 3.5.1.98) and possibly other proteins to yield deacetylated histones/other proteins. This group includes animal HDAC4,5,6,7,8,9,10, fungal HOS3 and HDA1, plant HDA5 and HDA15 as well as other eukaryotes, archaeal and bacterial histone-like deacetylases. Eukaryotic deacetylases mostly use histones (H2, H3, H4) as substrates for deacetylation; however, non-histone substrates are known (for example, tubulin). Substrates for prokaryotic histone-like deacetylases are not known. Histone acetylation/deacetylation process is important for mediation of transcriptional regulation of many genes. Histone deacetylases usually act via association with DNA binding proteins to target specific chromatin regions. Interaction partners of class II deacetylases include 14-3-3 proteins, MEF2 family of transcriptional factors, CtBP, calmodulin (CaM), SMRT, N-CoR, BCL6, HP1alpha and SUMO. Histone deacetylases play a role in the regulation of cell cycle, cell differentiation and survival. Class II mammalian HDACs are differentially inhibited by structurally diverse compounds with known antitumor activities, thus presenting them as potential drug targets for human diseases resulting from aberrant acetylation.	1.59819e-116
NC_018870.1\|WP_015050492.1\|1422985_1423489_-\|6,7-dimethyl-8-ribityllumazine-synthase	gnl\|CDD\|234606	PRK00061, ribH, 6,7-dimethyl-8-ribityllumazine synthase; Provisional.	3.01916e-84
NC_018870.1\|WP_015050489.1\|1419656_1420568_+\|DUF4338-domain-containing-protein	gnl\|CDD\|372975	pfam14236, DUF4338, Domain of unknown function (DUF4338). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 206 and 475 amino acids in length.	2.22924e-64
NC_018870.1\|WP_015050494.1\|1424742_1425393_-\|riboflavin-synthase	gnl\|CDD\|236455	PRK09289, PRK09289, riboflavin synthase.	9.60354e-107
NC_018870.1\|WP_015050495.1\|1425374_1426523_-\|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	gnl\|CDD\|273015	TIGR00326, eubact_ribD, riboflavin biosynthesis protein RibD. This model describes the ribD protein as found in Escherichia coli. The N-terminal domain includes the conserved zinc-binding site region captured in the model dCMP_cyt_deam and shared by proteins such as cytosine deaminase, mammalian apolipoprotein B mRNA editing protein, blasticidin-S deaminase, and Bacillus subtilis competence protein comEB. The C-terminal domain is homologous to the full length of yeast HTP reductase, a protein required for riboflavin biosynthesis. A number of archaeal proteins believed related to riboflavin biosynthesis contain only this C-terminal domain and are not found as full-length matches to this model. [Biosynthesis of cofactors, prosthetic groups, and carriers, Riboflavin, FMN, and FAD].	5.70566e-142
NC_018870.1\|WP_148275872.1\|1412029_1413358_-\|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	gnl\|CDD\|237675	PRK14328, PRK14328, (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional.	0
NC_018870.1\|WP_015050481.1\|1403188_1404133_-\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	gnl\|CDD\|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	3.49605e-154
NC_018870.1\|WP_015050493.1\|1423503_1424718_-\|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II	gnl\|CDD\|181774	PRK09311, PRK09311, bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II.	0
NC_018870.1\|WP_037999028.1\|1408963_1411588_-\|DNA-mismatch-repair-protein-MutS	gnl\|CDD\|235444	PRK05399, PRK05399, DNA mismatch repair protein MutS; Provisional.	0
NC_018870.1\|WP_015050484.1\|1407256_1408936_-\|hydantoinase/oxoprolinase-family-protein	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.35752e-90
NC_018870.1\|WP_015050491.1\|1422444_1423008_-\|phosphodiesterase	gnl\|CDD\|181869	PRK09453, PRK09453, phosphodiesterase; Provisional.	5.01262e-81
NC_018870.1\|WP_015050490.1\|1422259_1422448_+\|50S-ribosomal-protein-L28	gnl\|CDD\|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	2.10217e-19
NC_018870.1\|WP_015050480.1\|1402878_1403151_-\|RNA-chaperone-Hfq	gnl\|CDD\|379947	pfam17209, Hfq, Hfq protein.	1.89176e-39
NC_018870.1\|WP_015050486.1\|1411628_1412000_-\|YlbF-family-regulator	gnl\|CDD\|377611	pfam06133, Com_YlbF, Control of competence regulator ComK, YlbF/YmcA. YlbF Is a family of short Gram-positive and archaeal proteins that includes both YlbF and YmcA which may interact synergistically. The family is necessary for correct biofilm formation, as null mutants of ymcA and ylbF fail to form pellicles at air-liquid interfaces and grow on solid media as smooth, undifferentiated colonies. During development, YmcA, YlbF and YaaT, family PSPI, pfam04468, interact directly with one another forming a stable ternary complex, in vitro. All three proteins are required for competence, sporulation and the formation of biofilms. The YmcA-YlbF-YaaT complex affects the phosphotransfer between Spo0F and Spo0B, thus accelerating the production of Spo0A~P. The three processes of biofilm formation, mature spore formation and competence all require the active, phosphorylated form of Spo0A, as Spo0A-P.	4.60859e-19
NC_018870.1\|WP_015050500.1\|1430877_1431291_-\|transposase	gnl\|CDD\|372705	pfam13751, DDE_Tnp_1_6, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	7.16436e-13

>NC_018870.1|WP_015050489.1|1419656_1420568_+|DUF4338-domain-containing-protein
MRSWNPPFWIGDRLFTADDLALIKETVRQFKRLSRRELFATICENLPWKAPNGKLKIEACRLFLEQLEASGLIELPPKKNPPKRNVKKVAPLPCISREGPLKQYLPVTVDPVPLKEQPLWNATMAAYHPLGYRQPFGAHQRYWIHSRAEGRVEILGALLFAAAARKVAVRESWIGWTAVECKRFRYRIINNSRFLILPGVQIPHLASHALALVARRIRADWQKRYGYAPVLLETFVTPPHQGTCYRAANWQCIGETAGLGREPRRQKGSPVVRLMFVYPLVREWREELCAPAPVAGKCDEFDA
>NC_018870.1|WP_015050488.1|1413480_1414077_-|hypothetical-protein
MQEKILVIPRTALGKKRFFQGFLRDENAAFLKHILNESFFTGRDQAEYDRRYKQLINYIVVRHRDRIFIYQRIKETKEKRLLNKYSFGLGGHINPAPLNDFRELINFNFKRELREEIFFKGHYSYRYLGLLNDENTDVGRYHIGIVFFVSCSSQLITVREKNKLSGGLIPAERLDFYRPLLETWSALLLPEITCLLKQ
>NC_018870.1|WP_148275872.1|1412029_1413358_-|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB
MNSHDSEIMRAILEKNGYQWTERQEEADIFILNTCSVRRHAEQRAIGFLGNLKNLKERNPELIIAVGGCAPQNPEVREYLEKKAPHVDIIFGTRNYHRLPEFLNRVMVKRSRVIALDGEDEDLPGLLPAHHTSTVKAYVTIMYGCNNFCSYCIVPYTRGREKSRPLEEIYQEVQELAAKGYKEVMLLGQNVNSYGKDLPGAINFAKLLAHLDKIPGLARIRYMTSHPRDFDDELIETIAATRKVCEHFHLPLQAGSNRILQLMNRGYTREKYIQLTDKIKNKIPGASITTDIIVGFPGETEDDFLDTLDLVQTVRFDAAYTFMYSPRRGTPAAEMENQVPSEIKKDRLNRLVDVQNRITLEKNKLLEDHVVEVLVEGRSKNNPERWSGRTRTNKIVVFEGEENEDLTGQIVEIVISCAQTWTLFGTLKTVSAKKESSSQSRI
>NC_018870.1|WP_015050486.1|1411628_1412000_-|YlbF-family-regulator
MSVIEKAQELGYALRDTEEATILQAAEINLERDLESRNLISEFQQRFEMIKKAQDAGEEVSDEEWESFNQLQQKVKENKNIQAYFAAQKRFQSLLQQVNTIINKILRGESCSSGCSGDCSGCM
>NC_018870.1|WP_037999028.1|1408963_1411588_-|DNA-mismatch-repair-protein-MutS
MNQYQSIKNKYPDCLLFFRLGDFYELFGEDAIKASKELEIVLTSRGVSKDKKVPMCGVPYHAVDGYLKRLLEKGYKIAICEQLEEAKPGKGIVKRDVVRVITPGTVLEPAYLEQGENNYIISLYRKKESIGCAWSDISTGKFQMTQFSETAAAEYLRDLLSRLQPAECIIRSDQAAFFEPLMEDYWESKGLNITRLNKEINGQVAWELVTRQFGQENLIGIDRDAFETGLVSAANLLSYIMETQKTSTLPFKDLSVYTPKSCMYIDAMTRRNMELFRTLRDGKREGSLFWALDRTLTGMGTRLLRYWLESPLLDIEEIEARQEAVEELAGSFFLRNELQECLKKIYDLERIISRVDWQLAGPRDLLGLAKSLQVIPDLKEILGQAKSKMLREAGVELDPVADIKEMLFSALIDDPPANLKNGGIIRTGYHPEVDKLRNMIAEGEDWIRKLEARERVRTGIKSLKIDYNKVFGYYIEVTKPNLHLVPGDYIRKQTLTQAERFITTELKEQEALFLGATERLQDLEYQIFLDIRRQVGEASEKIRRNAGIIARIDCLVSFAETAARYHYTKPKINNSGVIRIKNGRHPVLEQLLPEGSFVPNDLEIGEDADRILILTGPNMAGKSTYMRQMALIVLMAQCGSLVPADEAEIGIVDRVFVRAGAFDDLGKGQSTFMMEMNEVSYIVHHATERSFIVLDEIGRGTGTFDGIGIAWAIIEYIHDKIGARTIFATHYHQLTQLADILHGVANCSVAVQEEGQNIVFLHKVVPGGTDKSYGIQVARLAHLPEELVQRAQEVAASMEGGSGNKSGKRTEDVRSAPVQLVLFDERSAILKELQNLNLVQMTPLEALNTLSNWQQRLAQTKETGHFRKRGRREQ
>NC_018870.1|WP_015050484.1|1407256_1408936_-|hydantoinase/oxoprolinase-family-protein
MLIGLDVGGTYTDAVLLEGREIIKKVKTPTDYEKLLNSLLAALDPLLEEAKGRAIERIVLSTTLITNLIATRRIEPVALVLIPGPGLNPDTFDYQVPLTISLSGAIDYRGREIEPLNEQELKECMEKIKDSGVRRIAVVGKFSQRNNKHEQKVATYLQEHIPDLEVIMGHQVTGRLNYPRRVYTTLLTLATQRRFREFYSEVQELLHRRGIKAPLYILKADGGTLPLEQSAAKPVETIFSGPAASTMGVLALTPRKQTSVVIDIGGTTTDLALILTGTPLLASKGARIDDQLTHVRAFATKSVAVGGDSCLRVRNGSLEILPYREGPAYCLGGPQPTPTDAMRVAGLTDIGDKDKAIDAMKILGKDLGLSVNRTAELTLKMMVRRITAEINSMFLAWEQEPAYRIWELRQKRKVRPQNLVGIGAASPALIPLLSKEMDCRPVIPQHAEVANAIGAALARVNLRLTFHFDTERNFYFIEENGVQERIPEPLHSLQDAEKFALGRLKEEGKKLGIITDDEPEIIYSELFNMVRGWRTTGRLIDVCVQFPTGVLVEWEEGGN
>NC_018870.1|WP_081578627.1|1405902_1407315_-|histone-deacetylase
MFAFSFQQVSSLSGKKEGIEVSRKTGLVFFPAFDWAITPTHPEREERLLYTRDQLFEEGVMDLPEIVEYKPRNADYKDIARVHFCVPDISAQITEAHLIAAGGTLVLADAFMNKEIDNGFALVRPPGHHSMRVVHGNRGFCNIHNEAIMIEYLRKNYGLQKIAIVDTDVHHGDGTQDIYYHDPDVLFISFHQDGRTLYPGSGFCNELGGPTAYGTTINIPLLPNTTDEGIHYVLDQLVLPLLEEFQPDIIINSAGQDNHYTDPLANMRFTARGYARLNEKLKPDLAVLEGGYAIESALPYVNMGIILAMAGIDYSWVREPDYRPENFRETPEHMAYLKGLVEHLQDAWHNREEMAAAGFPWDEEFFESSRMIYYDTDNIREQQQEKIRLCKRCPGYQVIRSRGLYPSGRIRTIQAIVLHRRACPSCQEEARELYRERIADPEGLDIIYLQDKPQDRYHQFTVSGESELQY
>NC_018870.1|WP_015050482.1|1404150_1405878_-|DNA-mismatch-repair-endonuclease-MutL
MGIIKLLAPEVVNQIAAGEVVERPVSVVKELLENAIDAAATQITVVIEDAGLKEIRVIDNGMGMTGEDAELAIARHATSKIRNAGDLDRVATLGFRGEALAAIASVSRLTLITRTAEMIAGTRIVVEGGEKKQVTSIGCPHGTQVIVRDLFFNSPPRRKFLKSIQAEKAAVADLLSRFALGYPEIALNFYSGKRLSLATPGQAEPIEIACILYGKEAKDNFLEIFYEGEGVRIRGIVSKPQFTRASRHYQTFFVNRRLVRNYHLSRALESAYEGLVTSGHYPCVAIYLDLEPKTIDVNVHPTKSDIRFADPALVARALYRAVRNTLANYQTQRRLSHQLLVEHKNHSSVHSLPGNGFNNWRNESAVCESAPLFYKPESECRQPFFREMRLIGQAQGLYIIAEKGDNIFIIDQHAAHERIRYEEIMKNMERKEYFAQKLSVPQEVRLSPEERIIYLDNKDLLKGVGYELKEAGTSSFLIISVPPGLNDDPGQLFREMLEVLRQERGIRENPMKFYEKVAMMSACKSAVKAGDILTTGEMRAILQQLDDTANPDNCPHGRPTYIRLAKSELDKRFFR
>NC_018870.1|WP_015050481.1|1403188_1404133_-|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA
MSTPLIVIAGPTAVGKSKIAVELALRLNGEIISADSVQLYKYFRIGTAKLTPEEQRGVPHHLLDILEPDDNFSVADFQKLARQKIEDIHGRGKLPFLVGGTGLYIQAVIDPYHFPEMKGQEEIRRKLRTIWEEGKGTELYRRLQEVDPAAAARIHPNDFRRISRALEVFYLTGKPISSYAQKKNTTTSYHLAMVGLISSRAELYKRIEKRVDQMFAQGLVQEVQSLLAKGYDPRLKPFQSLGYKQVVKYLSGVYDLNTAIQETKKATRNYAKRQLTWFRRDPRIRWFSLQGADYQKVVKRIEDYICRRIRVHVE
>NC_018870.1|WP_015050480.1|1402878_1403151_-|RNA-chaperone-Hfq
MGKQQIILQDFFLNQIRKEGIPVTIYLINGFQLKGTLRGFDNFTVILESEGKQQMVYKHAISTVMPLKALNLTFDSASGQDKEVVSIMMV
>NC_018870.1|WP_015050490.1|1422259_1422448_+|50S-ribosomal-protein-L28
MAKCAICGKGVRVGMRVSHSHVRTKRTWTPNLQPVRTVINGKPVRMKVCTRCLKAGKVKRAL
>NC_018870.1|WP_015050491.1|1422444_1423008_-|phosphodiesterase
MRIGIVSDTHGSLTAWERTITAVFRSVDLIVHAGDVLYHGPRNPLPEGYAPRELAAVINKAPLPVVIARGNCDAEVDQVLVSWPLLSPYAFLQIRDLRILVHHGHGLEHTEMQAQAQRYQVQLFIHGHTHIPLLEEKNGIIFLNPGSPSLPKGEGRRPTVALLEDNRVSLIDLDSGNSIKSLALPKA
>NC_018870.1|WP_015050492.1|1422985_1423489_-|6,7-dimethyl-8-ribityllumazine-synthase
MVRTFEGKLIGQGLRFGIVVSRFNEFITNRLLSGALDILVRHGVSREAIDVAWVPGAFEIPLAAQKMTGLGYDGVICLGAVIRGATPHFDYIASEVTKGIAQVGLKSGIPVVYGLITADTLEQAIERAGTKAGNKGADAAMTALEMANLFREMKEQGGVGHEDRDRQ
>NC_018870.1|WP_015050493.1|1423503_1424718_-|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II
MAELEFFNTIEEAIEEIRAGKMIIVVDDEDRENEGDLIIAAEKVTPEAINFMATYGRGLICVPMTGKRLDELDLQPMVAHNTDKHETAFTVSVDAATSTTGISAFERAATVRALIDPKTKPQDLRRPGHIFPLRAKEGGVLRRAGHTEAAVDLARLAGLYPAGVLCEIMNDDGTMARVPELMKFARKHNLKIITIADLIKYRRRTEKLVQKVTSTHLPTKYGEFTAVAYKSLLDDNCHIALIMGDLRGVEPVLTRVHSECLTGDVFGSLRCDCGDQLAQALKMIAAEGRGVLLYMRQEGRGIGLLNKIRAYELQDGGADTVEANELLGFPPDLRDYGIGAQILVDLGLKKIRLLTNNPRKIAGLVGYGLEVVERVPIEIPPREENRGYLRTKKEKLGHLLALKK
>NC_018870.1|WP_015050494.1|1424742_1425393_-|riboflavin-synthase
MFTGLIEERGTVRKITREHSSILLTIEAQKVLAGINLGESIAVNGACLTVTSSTADTFTVDVMPETLDKTNLGLLAPGSQVNLERSLQVGGRLGGHLVTGHVDATGEILRLNRRGIAVEMWIRLPSHLDRFLVPQGSVAIDGVSLTVAELQPDAFMVSLIPHTRRETTLGSKKIGDVVNIEADLLGKYVFYLVGRIMTPDNQKSITPQFLAEHGFI
>NC_018870.1|WP_015050495.1|1425374_1426523_-|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD
MGEESLKQHIRFMSRALELAALGKGKTSPNPMVGAVVVRDDVIIGEGYHMKAGTPHAEVHALRAAGDLAKGSTLYVTLEPCCHYGKTPPCTEAIIKAGIQKVVIATCDPNPLVAGKGIRSLKEAGIEVQVGIMEEEAQRLNEAFFKYIRTGLPYVVLKVAMSLDGKIATCSGDSKWITGEKARLKVQHLRAESDAVMVGIGTVLADDPLLTVRLPDESKRPLRVIVDSSLHLPVDSRLVQTAGEAPVVVAAVPGKYQKDKKLLLEKRGVEVLDMPGEDDMVSIEELLQELGRRGVMTLLLEGGATLNASALQADIVDKFVFFLSPLIIGGKNAPGAFGGSGFDTLDKALRLESLKIERVGEDFLISGYPAGRRVIDTCSRVL
>NC_018870.1|WP_028990991.1|1427063_1427267_+|hypothetical-protein
MRKLVNAYKDLVFLLALTVLSPSAFRASSASVKHKKLELTKIPDGHVRVEDNIKSTAILQLIVWKTD
>NC_018870.1|WP_028990990.1|1428716_1429571_-|LuxR-family-transcriptional-regulator
MPSFPKEPKRRDYFHYLCSAEELEASRARCRLLGVPVELGRPAKILTDSSLTQRLATNALLIALSEHVITPDCYTGPSENFLYILCDPELVALKIFAAPEVLVATEDLGIKPGTVFTEASCGTNALALAHEYNRLVATRGKQHYCKLFEDWWCIASPVTNQKGRTLGYLDISMPAAKELGLAVAFFKKLLKLIEQQLTTLEFRKVDHRPSDTPSPPPAGDPNYKALQLTSREEEILNLRLLGLDNQEIAARLCISPNTVKVHCARIYRKLGVHSFPQLIAKIYR
>NC_018870.1|WP_015050500.1|1430877_1431291_-|transposase
MKAYENRFVFNQRQKSACRSCAYQGFLCKAKRPSIVRKTKTELVDWVDQHLVTEKAQESIKKRAPWVETVFAEMKAVHGLSRAKLRGRVKVQIQVLFAMALHKIKQLLKLLKEPKRKGSQCCLLSFAISFRRLVFRS
>NC_018870.1|WP_028990989.1|1431732_1432086_-|hypothetical-protein
MGVSDKAGEVGLFLFIFGNNTFIAFLCLVLGKPSRAFFSTLVCSLNGTLAGAALVALSHWGVESSTHFPCHLCLNVGSLAAPATSGCLGLLIPSLVLMAAVSGNYADLVNWFTLRKT

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Crispr_ID: NC_018870_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018870_3

1915104-1923411

TypeI-D

I-A,III-B

Consensus_repeat	Method
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CRISPRCasFinder
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CRT
GTTGCACTAATTACCCCGATGAAAAGGGGACTGAAAG	PILER-CR

112 spacers

cas4,cas2,cas1,csc1gr5,csc2gr7,cas11d,cas10d,cas3HD

The CRISPR arrays of NC_018870_3

>merge|NC_018870|3|1915104-1923411|CRISPRCasFinder,CRT,PILER-CR
ATTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCGAAGATATTCATAGAAGAGCCATGCTCCACATTTGGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGTGGATAAGCACCCTTTGGGGCAGAAGAGACTGTGGGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCTCTTCCTCTAATTCTTTTTCGGATGAATGTGAAGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTCCAATTCCCTGCCAGCGGTTAAGACTCATATTGGTTCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCATATAATAGGGAGAACGCCAGCCGCTTTTTGCACTTACCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCCTTATAGCCGCCAGAACAGATACAAGATATTTTCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGTACTACTATTGGATTAATTTCTTTCTCCTTAGCGGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCTGCCTTGTCCCGTTCCATGCACTCAACGCACTGGCAGCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTTTTTGGATACCATGCGGGCCGACAAGCGACAGGTGCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGGCATTTCTGACCCGGCTATCCAGACCAGCGTGGTTTCCTCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCCTGAACCCGTCAGTGTGCGGTAATCAGTTCCCGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCACATAAGAGTCCAAATATACATTAATCCTCAGCCGGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGGCGGAAGCGATGTGCAAATGCGGTGGGATTATGGTGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCGATGTCAACGTACTGGATGTCGTTGGCGGCAGTGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGGCTTGAAACGACATGGGGTAAGATATCAGGATTTACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCGCATGACAGCTTGCTGGTAAGTATGTTCTACGACCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGGTAATTAGTTTGCTGTGGACACTGACCGGCACGGTCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTGAAGGTCGGACAATGGGAAGGTTTCTGGACGCACAACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACAAGATGAAATACCGGAAGAAGCGGGGTTGATTGTGAGACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTCTGGTGGAGCCATTATGTTGACACTAACTTTAACTAACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCGAAATAACTGATAGTTAAAAAGGAGGCTAACCAAAATGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTGACGCGCCTTTCATTGTTTATGTCGAGACTTTTTTGCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACAATGCAAACCCCCGCAGGGGCGGGGGCCTGGTGGTACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGGTGTCGAAATCGTCGGGTATGTCGAGAAGGTTTTTTTCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACAACGGAAACTCCAGCGGGTAATGAAGCGGTTAGGTGTTCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTATTTCGTCCTGGAGTCCGTGGCTATCGTAATGGAACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACACCGCCGGTCCGTGAGGTATCTGATGTGCAGAGCTAAACTCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTATATGTCTTGATGTTGACGATGATGGCAAAATAGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGATATGGGCAAGGATCGTTGGCAACCAGCGGCACTTGCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGAAACCTGGAAGAAAATGCTTGCTCCTATGAGTATTCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGAGAGTAGGACGCTCCCAATATTCCTTGACCAAAGCACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACATCGCTGGCCGCCACCGCCCCAATGTCAGCAGGGGTCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACAGCGGGAACATCTCGCCTTCCCGGAGCAGGTAAATCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACACTTCGACGCATCGGCAACCACGAAAGACGTGGCCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACACATTCACGGCAGCCTGGGCTTCTTCCAGCCCGGCCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACAGAAACGTCCGCAGTGAGTCCTGTCGGCGCAGGAACCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACAATGGCGGTATGGAACTTTGTAAGGTTGTCGAACTTACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACACCTATAGCTGGGGGACGGTGCACTCCACCCAAGCGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTACATTCTTTGCTGTCCTTGAAGAAGTTTAGTTAATTCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTTACACAAGGCTAATACTCCATCAAAGTCATCTTTCTGCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGTACCGGATGAGCGTGTATCTTCTGTATGAAGAGTCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCCGAACACCCTGCCCTAGGCGAACGAATTGGATGAACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACAATGAGAAAGAACGAGATTGTGAACTATCCGATTCACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTTTGGAGCGAGAAGTCCACGAGCTTTGGAATATGGAACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGCTAATAAAAGGCCGAATTTCTCGGCCTACGTCAAACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCGCAAGGGTGGGTGATAGTATATATGTTTTTATTCCAGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTCCTTAAGGGGTCTGCCATCACAAGAGCAGAATAAAGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTGTACGTTCATCATCAGTCTGTTTTATCTTTGTTACACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCCCTGCCACAGGGGTTCGACAAGCACGTTTCCCACGCCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGCCGGTGCCAAAGGCACGCCACAGGGTGCAACTTTATCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCCTTCGTAATCAGCATCCCATCCTTCCACTTTGTAAACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCAGATGGTCCGACTACGTGAGAGACAGCCTCGAAATCGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGCCGCGAGGCGGACAAGTGGGCGCCGAACTTCGTCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTGCGTTTTTCAGCTTGAGCCGTGGCAGCAGTTTATCGTCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACACAATCCAGCAGCTGACAACCACCCAGGACGCCGACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTTTGAAGCTCAGTTCGTCCGGTCGACTCCAGAAGGACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCTTTCAAGTACCCCTGCTTTGCCCAGGCCTTATACCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTAGCCAGATTCGGACTGTCATTTTGAACGGGGAGCCCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGCGACATATTCACGTTGCAGCGGTGGGTCCATAGACACCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTTCATTTCGGGTACGTGGACTAACAGCTGAGGAAACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTATGAAAGAATCCATCGAAAACCAAATTGAAGAAATCGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACATAGGTGGTACCGTTAATCTGATATCCACCCTTCACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACATACCCTTTGTAACAAAATTATTCGTGTGATTATACCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGGAGTAAGTTCAGTCAAGGAGATTGCGCCGTGAAAGGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCGGAACTCCCATTCCTCCGGGAAATACTTGGGTAAGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCAAAATTCTGCCTTATACCTGGAATATTGGCCGAATCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGACGGCCGAACTTGGCCGCGGCGGCCGCCAGGGCGTCCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCAAATACTCAATGGGAGTGGCTTTGCGGCTGTTGACACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTAGCGGAAGCGCAAGGCTCAGAGCTTGAGAAGCTGTATGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTAAAAAGGGCTGGGAGGAGGAGAAATATGACTTCATGTACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTCCTTCACCCAGGTCATGCTATCCACGCTATACCACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGGAGCAAAGTTCCCCGCTCCGCTCAACCTATAACAGGACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACAGAGAAACGAGGGAAAACTTTTATGCTGTTGGAGATCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCGTGCTTGGCGTACTGGTCCAGCTCGTTCAGATAGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACACTGTGACCCTTCCACGCTTGGGCATCCCAATTACCCTGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACACCTCCGGGTGGATGCCGCCGGCGCCGACCTGACCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGCGGAAGAACGCTGAAAGACCCTATTTCAATTAAGATCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGTATTTGGCTTATAAATCTCACGTTGGCTGGGTTGCACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTCCTCAGGTTTTTTAGAATTACAGCAAATAACTTGATCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGGTCCTGAAATTGAGGGTGAGGGTCATAGCGTCAAAACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACAAAAGGAAGCGCGGTGCCTTTAATCGCAATAGTGGACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTTAATGTCTGCAACGAGAGCGAATTTTTCAGACTTCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACAAGATTAAAGCAAATAATGGAGGCTCGTAATCTGAGACCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCGCCAATTATGTGACCGCCGCACTGCAGGGTTAAGGACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCAAATTCAAGCCTGTCGTCCTGGGTATCAACGCCACCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTGAAATGAAGTTGACGCTGAAAATCACTTTGACTCACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGATGTAGTCTTCTTCTCCAGGAAGGGAGAAAACGACCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTTCTGATATGCGGATATATCCGACTGTGTTTTACTGACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGTTGCTAATAGGGTTTGTATCGAGATACGCGAATATGACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACATAATGCAAATTGCCTGGGCTATGGCCAAGGCCGATGCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACATTTATATCAAATTTCATTTCTTTGACGGTGAAAGCCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCAGAAAGAGATAGTTTGTTCAAGCTAGCAGACCAGCGAACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGCCGGCGGCCGCTGAACTGGCAAACTTATATATCGAACTCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTCATAAACATATTTACAGGCCAGTTTGTAGTCGGTACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACAATTGAAAAACCCCTGATTCGTCTTTCCTGGCCGTTCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTGGAAAAACTTTATATGACCGTTACGGTTAATTAACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCCCGACCGGGGGATAACTGGCACCTTCCTGGTACAGACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACAACTAAGAGAAACCGGGCTGACCGCCGAGCAGGTACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACTGCTTTGAATTTGTCCAATGCAAGGTTTGAATTGCAAACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCGTGGTAATATGATATCGGGAGCCGTTTGAGAGGAGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACAGCTCAACGAGCTGGCGTTGTCCTTTAATCAGGTTGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCCTGGCGTAAGCGATCAAATTGGCTCTCCATGCCCTCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACAGAATACCATCTCAAAGTCCTCGCCTCGCTCCCAGAGCCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGGGTGTGGGCACGAAGCATTCAAAGTGTACTTTGAAGACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCAGATCGGAATTCTATGGCGCCGCTACTGCCGGATTGCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACCCCTGAAGAGTAAAAGAAAACACAATAGCCGTCCGGGACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGATTTTGTTTGTCGAACCATATCATCCGACTTCCACCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACAGCCCGTTGATATTTTGAATTGCACATACTTTACATTACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACAGCAGTACGGACGGGATTAAGAAGGGGTGAATTGTTCTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGAGTGCAGCAGGCCAGCCAGTGCGGGCTTCAGCGATGACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACGAGTTATTATTGGCGCATAGCTGCCCGTGATACAACACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACACCTATATCCCTTGGTATATTGGGGCTTTGATGAAACTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC

>NC_018870|3|3|1915104-1923411|CRISPRCasFinder
ATTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGAAGATATTCATAGAAGAGCCATGCTCCACATTTGG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GTGGATAAGCACCCTTTGGGGCAGAAGAGACTGTGGG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CTCTTCCTCTAATTCTTTTTCGGATGAATGTGAAG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TCCAATTCCCTGCCAGCGGTTAAGACTCATATTGGTT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CATATAATAGGGAGAACGCCAGCCGCTTTTTGCACTTAC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CCTTATAGCCGCCAGAACAGATACAAGATATTTTC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GTACTACTATTGGATTAATTTCTTTCTCCTTAGCGG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CTGCCTTGTCCCGTTCCATGCACTCAACGCACTGGCAGC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TTTTTGGATACCATGCGGGCCGACAAGCGACAGGTGC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGCATTTCTGACCCGGCTATCCAGACCAGCGTGGTTTCCT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CCTGAACCCGTCAGTGTGCGGTAATCAGTTCCCG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CACATAAGAGTCCAAATATACATTAATCCTCAGCCGG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGCGGAAGCGATGTGCAAATGCGGTGGGATTATGGTG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGATGTCAACGTACTGGATGTCGTTGGCGGCAGTG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGCTTGAAACGACATGGGGTAAGATATCAGGATTTA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGCATGACAGCTTGCTGGTAAGTATGTTCTACGACC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGTAATTAGTTTGCTGTGGACACTGACCGGCACGGT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TGAAGGTCGGACAATGGGAAGGTTTCTGGACGCACAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AAGATGAAATACCGGAAGAAGCGGGGTTGATTGTGAGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TCTGGTGGAGCCATTATGTTGACACTAACTTTAACTAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGAAATAACTGATAGTTAAAAAGGAGGCTAACCAAAATG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TGACGCGCCTTTCATTGTTTATGTCGAGACTTTTTTGC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AATGCAAACCCCCGCAGGGGCGGGGGCCTGGTGGTA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGTGTCGAAATCGTCGGGTATGTCGAGAAGGTTTTTTT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AACGGAAACTCCAGCGGGTAATGAAGCGGTTAGGTGTTC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TATTTCGTCCTGGAGTCCGTGGCTATCGTAATGGAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ACCGCCGGTCCGTGAGGTATCTGATGTGCAGAGCTAAACT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TATATGTCTTGATGTTGACGATGATGGCAAAATAG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GATATGGGCAAGGATCGTTGGCAACCAGCGGCACTTGC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GAAACCTGGAAGAAAATGCTTGCTCCTATGAGTATTC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GAGAGTAGGACGCTCCCAATATTCCTTGACCAAAGCA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ATCGCTGGCCGCCACCGCCCCAATGTCAGCAGGGGTC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AGCGGGAACATCTCGCCTTCCCGGAGCAGGTAAATC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ACTTCGACGCATCGGCAACCACGAAAGACGTGGCC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ACATTCACGGCAGCCTGGGCTTCTTCCAGCCCGGCC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AGAAACGTCCGCAGTGAGTCCTGTCGGCGCAGGAAC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AATGGCGGTATGGAACTTTGTAAGGTTGTCGAACTTA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ACCTATAGCTGGGGGACGGTGCACTCCACCCAAGCG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TACATTCTTTGCTGTCCTTGAAGAAGTTTAGTTAATT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TTACACAAGGCTAATACTCCATCAAAGTCATCTTTCTGC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GTACCGGATGAGCGTGTATCTTCTGTATGAAGAGT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CCGAACACCCTGCCCTAGGCGAACGAATTGGATGAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AATGAGAAAGAACGAGATTGTGAACTATCCGATTCA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TTTGGAGCGAGAAGTCCACGAGCTTTGGAATATGGAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GCTAATAAAAGGCCGAATTTCTCGGCCTACGTCAAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGCAAGGGTGGGTGATAGTATATATGTTTTTATTCCAG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TCCTTAAGGGGTCTGCCATCACAAGAGCAGAATAAAG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TGTACGTTCATCATCAGTCTGTTTTATCTTTGTTACA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CCCTGCCACAGGGGTTCGACAAGCACGTTTCCCACGCC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GCCGGTGCCAAAGGCACGCCACAGGGTGCAACTTTAT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CCTTCGTAATCAGCATCCCATCCTTCCACTTTGTAAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CAGATGGTCCGACTACGTGAGAGACAGCCTCGAAATCG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GCCGCGAGGCGGACAAGTGGGCGCCGAACTTCGTC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TGCGTTTTTCAGCTTGAGCCGTGGCAGCAGTTTATCGT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ACAATCCAGCAGCTGACAACCACCCAGGACGCCGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TTTGAAGCTCAGTTCGTCCGGTCGACTCCAGAAGGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CTTTCAAGTACCCCTGCTTTGCCCAGGCCTTATAC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TAGCCAGATTCGGACTGTCATTTTGAACGGGGAGCCC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GCGACATATTCACGTTGCAGCGGTGGGTCCATAGACAC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TTCATTTCGGGTACGTGGACTAACAGCTGAGGAAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TATGAAAGAATCCATCGAAAACCAAATTGAAGAAATCG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ATAGGTGGTACCGTTAATCTGATATCCACCCTTCA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ATACCCTTTGTAACAAAATTATTCGTGTGATTATAC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGAGTAAGTTCAGTCAAGGAGATTGCGCCGTGAAAGG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGGAACTCCCATTCCTCCGGGAAATACTTGGGTAAG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CAAAATTCTGCCTTATACCTGGAATATTGGCCGAAT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GACGGCCGAACTTGGCCGCGGCGGCCGCCAGGGCGTCC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CAAATACTCAATGGGAGTGGCTTTGCGGCTGTTGACA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TAGCGGAAGCGCAAGGCTCAGAGCTTGAGAAGCTGTATG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TAAAAAGGGCTGGGAGGAGGAGAAATATGACTTCATGTA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TCCTTCACCCAGGTCATGCTATCCACGCTATACCA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGAGCAAAGTTCCCCGCTCCGCTCAACCTATAACAGGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AGAGAAACGAGGGAAAACTTTTATGCTGTTGGAGAT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGTGCTTGGCGTACTGGTCCAGCTCGTTCAGATAG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ACTGTGACCCTTCCACGCTTGGGCATCCCAATTACCCTG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ACCTCCGGGTGGATGCCGCCGGCGCCGACCTGACC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GCGGAAGAACGCTGAAAGACCCTATTTCAATTAAGAT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GTATTTGGCTTATAAATCTCACGTTGGCTGGGTTGCA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TCCTCAGGTTTTTTAGAATTACAGCAAATAACTTGAT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGTCCTGAAATTGAGGGTGAGGGTCATAGCGTCAAAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AAAAGGAAGCGCGGTGCCTTTAATCGCAATAGTGGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TTAATGTCTGCAACGAGAGCGAATTTTTCAGACTTC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AAGATTAAAGCAAATAATGGAGGCTCGTAATCTGAGAC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGCCAATTATGTGACCGCCGCACTGCAGGGTTAAGGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CAAATTCAAGCCTGTCGTCCTGGGTATCAACGCCAC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TGAAATGAAGTTGACGCTGAAAATCACTTTGACTCA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GATGTAGTCTTCTTCTCCAGGAAGGGAGAAAACGACC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TTCTGATATGCGGATATATCCGACTGTGTTTTACTGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GTTGCTAATAGGGTTTGTATCGAGATACGCGAATATGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ATAATGCAAATTGCCTGGGCTATGGCCAAGGCCGATGC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ATTTATATCAAATTTCATTTCTTTGACGGTGAAAGCC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CAGAAAGAGATAGTTTGTTCAAGCTAGCAGACCAGCGAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GCCGGCGGCCGCTGAACTGGCAAACTTATATATCGAACT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TCATAAACATATTTACAGGCCAGTTTGTAGTCGGTA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AATTGAAAAACCCCTGATTCGTCTTTCCTGGCCGTT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TGGAAAAACTTTATATGACCGTTACGGTTAATTAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CCCGACCGGGGGATAACTGGCACCTTCCTGGTACAGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AACTAAGAGAAACCGGGCTGACCGCCGAGCAGGTA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TGCTTTGAATTTGTCCAATGCAAGGTTTGAATTGCAAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGTGGTAATATGATATCGGGAGCCGTTTGAGAGGAG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AGCTCAACGAGCTGGCGTTGTCCTTTAATCAGGTTG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CCTGGCGTAAGCGATCAAATTGGCTCTCCATGCCCT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AGAATACCATCTCAAAGTCCTCGCCTCGCTCCCAGAGC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGGTGTGGGCACGAAGCATTCAAAGTGTACTTTGAAGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CAGATCGGAATTCTATGGCGCCGCTACTGCCGGATTG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CCCTGAAGAGTAAAAGAAAACACAATAGCCGTCCGGGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GATTTTGTTTGTCGAACCATATCATCCGACTTCCAC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AGCCCGTTGATATTTTGAATTGCACATACTTTACATTA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AGCAGTACGGACGGGATTAAGAAGGGGTGAATTGTT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GAGTGCAGCAGGCCAGCCAGTGCGGGCTTCAGCGATGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GAGTTATTATTGGCGCATAGCTGCCCGTGATACAACA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ACCTATATCCCTTGGTATATTGGGGCTTTGATGAAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC

>NC_018870|3|2|1915104-1923411|CRT
ATTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGAAGATATTCATAGAAGAGCCATGCTCCACATTTGG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GTGGATAAGCACCCTTTGGGGCAGAAGAGACTGTGGG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CTCTTCCTCTAATTCTTTTTCGGATGAATGTGAAG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TCCAATTCCCTGCCAGCGGTTAAGACTCATATTGGTT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CATATAATAGGGAGAACGCCAGCCGCTTTTTGCACTTAC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CCTTATAGCCGCCAGAACAGATACAAGATATTTTC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GTACTACTATTGGATTAATTTCTTTCTCCTTAGCGG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CTGCCTTGTCCCGTTCCATGCACTCAACGCACTGGCAGC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TTTTTGGATACCATGCGGGCCGACAAGCGACAGGTGC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGCATTTCTGACCCGGCTATCCAGACCAGCGTGGTTTCCT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CCTGAACCCGTCAGTGTGCGGTAATCAGTTCCCG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CACATAAGAGTCCAAATATACATTAATCCTCAGCCGG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGCGGAAGCGATGTGCAAATGCGGTGGGATTATGGTG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGATGTCAACGTACTGGATGTCGTTGGCGGCAGTG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGCTTGAAACGACATGGGGTAAGATATCAGGATTTA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGCATGACAGCTTGCTGGTAAGTATGTTCTACGACC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGTAATTAGTTTGCTGTGGACACTGACCGGCACGGT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TGAAGGTCGGACAATGGGAAGGTTTCTGGACGCACAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AAGATGAAATACCGGAAGAAGCGGGGTTGATTGTGAGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TCTGGTGGAGCCATTATGTTGACACTAACTTTAACTAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGAAATAACTGATAGTTAAAAAGGAGGCTAACCAAAATG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TGACGCGCCTTTCATTGTTTATGTCGAGACTTTTTTGC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AATGCAAACCCCCGCAGGGGCGGGGGCCTGGTGGTA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGTGTCGAAATCGTCGGGTATGTCGAGAAGGTTTTTTT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AACGGAAACTCCAGCGGGTAATGAAGCGGTTAGGTGTTC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TATTTCGTCCTGGAGTCCGTGGCTATCGTAATGGAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ACCGCCGGTCCGTGAGGTATCTGATGTGCAGAGCTAAACT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TATATGTCTTGATGTTGACGATGATGGCAAAATAG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GATATGGGCAAGGATCGTTGGCAACCAGCGGCACTTGC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GAAACCTGGAAGAAAATGCTTGCTCCTATGAGTATTC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GAGAGTAGGACGCTCCCAATATTCCTTGACCAAAGCA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ATCGCTGGCCGCCACCGCCCCAATGTCAGCAGGGGTC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AGCGGGAACATCTCGCCTTCCCGGAGCAGGTAAATC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ACTTCGACGCATCGGCAACCACGAAAGACGTGGCC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ACATTCACGGCAGCCTGGGCTTCTTCCAGCCCGGCC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AGAAACGTCCGCAGTGAGTCCTGTCGGCGCAGGAAC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AATGGCGGTATGGAACTTTGTAAGGTTGTCGAACTTA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ACCTATAGCTGGGGGACGGTGCACTCCACCCAAGCG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TACATTCTTTGCTGTCCTTGAAGAAGTTTAGTTAATT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TTACACAAGGCTAATACTCCATCAAAGTCATCTTTCTGC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GTACCGGATGAGCGTGTATCTTCTGTATGAAGAGT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CCGAACACCCTGCCCTAGGCGAACGAATTGGATGAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AATGAGAAAGAACGAGATTGTGAACTATCCGATTCA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TTTGGAGCGAGAAGTCCACGAGCTTTGGAATATGGAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GCTAATAAAAGGCCGAATTTCTCGGCCTACGTCAAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGCAAGGGTGGGTGATAGTATATATGTTTTTATTCCAG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TCCTTAAGGGGTCTGCCATCACAAGAGCAGAATAAAG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TGTACGTTCATCATCAGTCTGTTTTATCTTTGTTACA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CCCTGCCACAGGGGTTCGACAAGCACGTTTCCCACGCC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GCCGGTGCCAAAGGCACGCCACAGGGTGCAACTTTAT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CCTTCGTAATCAGCATCCCATCCTTCCACTTTGTAAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CAGATGGTCCGACTACGTGAGAGACAGCCTCGAAATCG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GCCGCGAGGCGGACAAGTGGGCGCCGAACTTCGTC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TGCGTTTTTCAGCTTGAGCCGTGGCAGCAGTTTATCGT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ACAATCCAGCAGCTGACAACCACCCAGGACGCCGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TTTGAAGCTCAGTTCGTCCGGTCGACTCCAGAAGGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CTTTCAAGTACCCCTGCTTTGCCCAGGCCTTATAC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TAGCCAGATTCGGACTGTCATTTTGAACGGGGAGCCC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GCGACATATTCACGTTGCAGCGGTGGGTCCATAGACAC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TTCATTTCGGGTACGTGGACTAACAGCTGAGGAAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TATGAAAGAATCCATCGAAAACCAAATTGAAGAAATCG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ATAGGTGGTACCGTTAATCTGATATCCACCCTTCA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ATACCCTTTGTAACAAAATTATTCGTGTGATTATAC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGAGTAAGTTCAGTCAAGGAGATTGCGCCGTGAAAGG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGGAACTCCCATTCCTCCGGGAAATACTTGGGTAAG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CAAAATTCTGCCTTATACCTGGAATATTGGCCGAAT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GACGGCCGAACTTGGCCGCGGCGGCCGCCAGGGCGTCC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CAAATACTCAATGGGAGTGGCTTTGCGGCTGTTGACA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TAGCGGAAGCGCAAGGCTCAGAGCTTGAGAAGCTGTATG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TAAAAAGGGCTGGGAGGAGGAGAAATATGACTTCATGTA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TCCTTCACCCAGGTCATGCTATCCACGCTATACCA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGAGCAAAGTTCCCCGCTCCGCTCAACCTATAACAGGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AGAGAAACGAGGGAAAACTTTTATGCTGTTGGAGAT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGTGCTTGGCGTACTGGTCCAGCTCGTTCAGATAG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ACTGTGACCCTTCCACGCTTGGGCATCCCAATTACCCTG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ACCTCCGGGTGGATGCCGCCGGCGCCGACCTGACC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GCGGAAGAACGCTGAAAGACCCTATTTCAATTAAGAT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GTATTTGGCTTATAAATCTCACGTTGGCTGGGTTGCA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TCCTCAGGTTTTTTAGAATTACAGCAAATAACTTGAT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGTCCTGAAATTGAGGGTGAGGGTCATAGCGTCAAAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AAAAGGAAGCGCGGTGCCTTTAATCGCAATAGTGGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TTAATGTCTGCAACGAGAGCGAATTTTTCAGACTTC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AAGATTAAAGCAAATAATGGAGGCTCGTAATCTGAGAC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGCCAATTATGTGACCGCCGCACTGCAGGGTTAAGGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CAAATTCAAGCCTGTCGTCCTGGGTATCAACGCCAC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TGAAATGAAGTTGACGCTGAAAATCACTTTGACTCA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GATGTAGTCTTCTTCTCCAGGAAGGGAGAAAACGACC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TTCTGATATGCGGATATATCCGACTGTGTTTTACTGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GTTGCTAATAGGGTTTGTATCGAGATACGCGAATATGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ATAATGCAAATTGCCTGGGCTATGGCCAAGGCCGATGC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ATTTATATCAAATTTCATTTCTTTGACGGTGAAAGCC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CAGAAAGAGATAGTTTGTTCAAGCTAGCAGACCAGCGAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GCCGGCGGCCGCTGAACTGGCAAACTTATATATCGAACT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TCATAAACATATTTACAGGCCAGTTTGTAGTCGGTA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AATTGAAAAACCCCTGATTCGTCTTTCCTGGCCGTT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TGGAAAAACTTTATATGACCGTTACGGTTAATTAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CCCGACCGGGGGATAACTGGCACCTTCCTGGTACAGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AACTAAGAGAAACCGGGCTGACCGCCGAGCAGGTA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	TGCTTTGAATTTGTCCAATGCAAGGTTTGAATTGCAAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CGTGGTAATATGATATCGGGAGCCGTTTGAGAGGAG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AGCTCAACGAGCTGGCGTTGTCCTTTAATCAGGTTG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CCTGGCGTAAGCGATCAAATTGGCTCTCCATGCCCT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AGAATACCATCTCAAAGTCCTCGCCTCGCTCCCAGAGC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GGGTGTGGGCACGAAGCATTCAAAGTGTACTTTGAAGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CAGATCGGAATTCTATGGCGCCGCTACTGCCGGATTG
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	CCCTGAAGAGTAAAAGAAAACACAATAGCCGTCCGGGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GATTTTGTTTGTCGAACCATATCATCCGACTTCCAC
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AGCCCGTTGATATTTTGAATTGCACATACTTTACATTA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	AGCAGTACGGACGGGATTAAGAAGGGGTGAATTGTT
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GAGTGCAGCAGGCCAGCCAGTGCGGGCTTCAGCGATGA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	GAGTTATTATTGGCGCATAGCTGCCCGTGATACAACA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC	ACCTATATCCCTTGGTATATTGGGGCTTTGATGAAA
CTTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC

>NC_018870|3|2|1915105-1923411|PILER-CR
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	GAAGATATTCATAGAAGAGCCATGCTCCACATTTGGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	TGGATAAGCACCCTTTGGGGCAGAAGAGACTGTGGGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	TCTTCCTCTAATTCTTTTTCGGATGAATGTGAAGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	CCAATTCCCTGCCAGCGGTTAAGACTCATATTGGTTC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	ATATAATAGGGAGAACGCCAGCCGCTTTTTGCACTTACC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	CTTATAGCCGCCAGAACAGATACAAGATATTTTCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	TACTACTATTGGATTAATTTCTTTCTCCTTAGCGGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	TGCCTTGTCCCGTTCCATGCACTCAACGCACTGGCAGCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	TTTTGGATACCATGCGGGCCGACAAGCGACAGGTGCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	GCATTTCTGACCCGGCTATCCAGACCAGCGTGGTTTCCTC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	CTGAACCCGTCAGTGTGCGGTAATCAGTTCCCGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	ACATAAGAGTCCAAATATACATTAATCCTCAGCCGGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	GCGGAAGCGATGTGCAAATGCGGTGGGATTATGGTGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	GATGTCAACGTACTGGATGTCGTTGGCGGCAGTGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	GCTTGAAACGACATGGGGTAAGATATCAGGATTTAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	GCATGACAGCTTGCTGGTAAGTATGTTCTACGACCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	GTAATTAGTTTGCTGTGGACACTGACCGGCACGGTC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	GAAGGTCGGACAATGGGAAGGTTTCTGGACGCACAAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	AGATGAAATACCGGAAGAAGCGGGGTTGATTGTGAGAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	CTGGTGGAGCCATTATGTTGACACTAACTTTAACTAAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	GAAATAACTGATAGTTAAAAAGGAGGCTAACCAAAATGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	GACGCGCCTTTCATTGTTTATGTCGAGACTTTTTTGCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	ATGCAAACCCCCGCAGGGGCGGGGGCCTGGTGGTAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	GTGTCGAAATCGTCGGGTATGTCGAGAAGGTTTTTTTC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	ACGGAAACTCCAGCGGGTAATGAAGCGGTTAGGTGTTCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	ATTTCGTCCTGGAGTCCGTGGCTATCGTAATGGAAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	CCGCCGGTCCGTGAGGTATCTGATGTGCAGAGCTAAACTC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	ATATGTCTTGATGTTGACGATGATGGCAAAATAGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	ATATGGGCAAGGATCGTTGGCAACCAGCGGCACTTGCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	AAACCTGGAAGAAAATGCTTGCTCCTATGAGTATTCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	AGAGTAGGACGCTCCCAATATTCCTTGACCAAAGCAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	TCGCTGGCCGCCACCGCCCCAATGTCAGCAGGGGTCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	GCGGGAACATCTCGCCTTCCCGGAGCAGGTAAATCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	CTTCGACGCATCGGCAACCACGAAAGACGTGGCCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	CATTCACGGCAGCCTGGGCTTCTTCCAGCCCGGCCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	GAAACGTCCGCAGTGAGTCCTGTCGGCGCAGGAACC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	ATGGCGGTATGGAACTTTGTAAGGTTGTCGAACTTAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	CCTATAGCTGGGGGACGGTGCACTCCACCCAAGCGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	ACATTCTTTGCTGTCCTTGAAGAAGTTTAGTTAATTC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	TACACAAGGCTAATACTCCATCAAAGTCATCTTTCTGCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	TACCGGATGAGCGTGTATCTTCTGTATGAAGAGTC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	CGAACACCCTGCCCTAGGCGAACGAATTGGATGAAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	ATGAGAAAGAACGAGATTGTGAACTATCCGATTCAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	TTGGAGCGAGAAGTCCACGAGCTTTGGAATATGGAAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	CTAATAAAAGGCCGAATTTCTCGGCCTACGTCAAAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	GCAAGGGTGGGTGATAGTATATATGTTTTTATTCCAGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	CCTTAAGGGGTCTGCCATCACAAGAGCAGAATAAAGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	GTACGTTCATCATCAGTCTGTTTTATCTTTGTTACAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	CCTGCCACAGGGGTTCGACAAGCACGTTTCCCACGCCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	CCGGTGCCAAAGGCACGCCACAGGGTGCAACTTTATC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	CTTCGTAATCAGCATCCCATCCTTCCACTTTGTAAAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	AGATGGTCCGACTACGTGAGAGACAGCCTCGAAATCGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	CCGCGAGGCGGACAAGTGGGCGCCGAACTTCGTCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	GCGTTTTTCAGCTTGAGCCGTGGCAGCAGTTTATCGTC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	CAATCCAGCAGCTGACAACCACCCAGGACGCCGAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	TTGAAGCTCAGTTCGTCCGGTCGACTCCAGAAGGAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	TTTCAAGTACCCCTGCTTTGCCCAGGCCTTATACC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	AGCCAGATTCGGACTGTCATTTTGAACGGGGAGCCCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	CGACATATTCACGTTGCAGCGGTGGGTCCATAGACACC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	TCATTTCGGGTACGTGGACTAACAGCTGAGGAAAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	ATGAAAGAATCCATCGAAAACCAAATTGAAGAAATCGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	TAGGTGGTACCGTTAATCTGATATCCACCCTTCAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	TACCCTTTGTAACAAAATTATTCGTGTGATTATACC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	GAGTAAGTTCAGTCAAGGAGATTGCGCCGTGAAAGGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	GGAACTCCCATTCCTCCGGGAAATACTTGGGTAAGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	AAAATTCTGCCTTATACCTGGAATATTGGCCGAATC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	ACGGCCGAACTTGGCCGCGGCGGCCGCCAGGGCGTCCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	AAATACTCAATGGGAGTGGCTTTGCGGCTGTTGACAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	AGCGGAAGCGCAAGGCTCAGAGCTTGAGAAGCTGTATGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	AAAAAGGGCTGGGAGGAGGAGAAATATGACTTCATGTAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	CCTTCACCCAGGTCATGCTATCCACGCTATACCAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	GAGCAAAGTTCCCCGCTCCGCTCAACCTATAACAGGAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	GAGAAACGAGGGAAAACTTTTATGCTGTTGGAGATC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	GTGCTTGGCGTACTGGTCCAGCTCGTTCAGATAGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	CTGTGACCCTTCCACGCTTGGGCATCCCAATTACCCTGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	CCTCCGGGTGGATGCCGCCGGCGCCGACCTGACCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	CGGAAGAACGCTGAAAGACCCTATTTCAATTAAGATC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	TATTTGGCTTATAAATCTCACGTTGGCTGGGTTGCAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	CCTCAGGTTTTTTAGAATTACAGCAAATAACTTGATC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	GTCCTGAAATTGAGGGTGAGGGTCATAGCGTCAAAAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	AAAGGAAGCGCGGTGCCTTTAATCGCAATAGTGGAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	TAATGTCTGCAACGAGAGCGAATTTTTCAGACTTCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	AGATTAAAGCAAATAATGGAGGCTCGTAATCTGAGACC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	GCCAATTATGTGACCGCCGCACTGCAGGGTTAAGGAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	AAATTCAAGCCTGTCGTCCTGGGTATCAACGCCACC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	GAAATGAAGTTGACGCTGAAAATCACTTTGACTCAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	ATGTAGTCTTCTTCTCCAGGAAGGGAGAAAACGACCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	TCTGATATGCGGATATATCCGACTGTGTTTTACTGAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	TTGCTAATAGGGTTTGTATCGAGATACGCGAATATGAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	TAATGCAAATTGCCTGGGCTATGGCCAAGGCCGATGCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	TTTATATCAAATTTCATTTCTTTGACGGTGAAAGCCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	AGAAAGAGATAGTTTGTTCAAGCTAGCAGACCAGCGAAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	CCGGCGGCCGCTGAACTGGCAAACTTATATATCGAACTC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	CATAAACATATTTACAGGCCAGTTTGTAGTCGGTAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	ATTGAAAAACCCCTGATTCGTCTTTCCTGGCCGTTC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	GGAAAAACTTTATATGACCGTTACGGTTAATTAAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	CCGACCGGGGGATAACTGGCACCTTCCTGGTACAGAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	ACTAAGAGAAACCGGGCTGACCGCCGAGCAGGTAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACT	GCTTTGAATTTGTCCAATGCAAGGTTTGAATTGCAAAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	GTGGTAATATGATATCGGGAGCCGTTTGAGAGGAGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	GCTCAACGAGCTGGCGTTGTCCTTTAATCAGGTTGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	CTGGCGTAAGCGATCAAATTGGCTCTCCATGCCCTC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	GAATACCATCTCAAAGTCCTCGCCTCGCTCCCAGAGCC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	GGTGTGGGCACGAAGCATTCAAAGTGTACTTTGAAGAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	AGATCGGAATTCTATGGCGCCGCTACTGCCGGATTGC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACC	CCTGAAGAGTAAAAGAAAACACAATAGCCGTCCGGGAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	ATTTTGTTTGTCGAACCATATCATCCGACTTCCACC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	GCCCGTTGATATTTTGAATTGCACATACTTTACATTAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	GCAGTACGGACGGGATTAAGAAGGGGTGAATTGTTC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	AGTGCAGCAGGCCAGCCAGTGCGGGCTTCAGCGATGAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACG	AGTTATTATTGGCGCATAGCTGCCCGTGATACAACAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAACA	CCTATATCCCTTGGTATATTGGGGCTTTGATGAAAC
TTTCAGTCCCCTTTTCATCGGGGTAATTAGTGCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018870.1\|WP_015050976.1\|1929665_1931726_-\|hypothetical-protein	cas10d	mkCas0103_cas10d_CAS-I-D	unknown
NC_018870.1\|WP_015050975.1\|1928996_1929623_-\|hypothetical-protein	cas11d	mkCas0094_cas11d_CAS-I-D	unknown
NC_018870.1\|WP_015050967.1\|1914094_1915081_-\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015050972.1\|1926825_1927182_-\|DUF4282-domain-containing-protein	unknown	unknown	gnl\|CDD\|379475
NC_018870.1\|WP_015050961.1\|1908075_1908285_-\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_148276000.1\|1909136_1910051_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NC_018870.1\|WP_015050958.1\|1905664_1905904_+\|ferrous-iron-transport-protein-A	unknown	unknown	gnl\|CDD\|377199
NC_018870.1\|WP_148275896.1\|1905344_1905596_-\|CGGC-domain-containing-protein	unknown	unknown	gnl\|CDD\|198146
NC_018870.1\|WP_015050964.1\|1910569_1911832_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224160
NC_018870.1\|WP_028990910.1\|1908329_1908992_-\|CoA-pyrophosphatase	unknown	unknown	gnl\|CDD\|239518
NC_018870.1\|WP_028990906.1\|1925681_1926692_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187766
NC_018870.1\|WP_015050970.1\|1925348_1925651_-\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|378256
NC_018870.1\|WP_015050977.1\|1931722_1932487_-\|hypothetical-protein	cas3HD	cd09641_cas3HD_CAS-I	gnl\|CDD\|193608
NC_018870.1\|WP_028990907.1\|1924732_1925311_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
NC_018870.1\|WP_015050966.1\|1913031_1914006_-\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015050973.1\|1927203_1927986_-\|hypothetical-protein	csc1gr5	mkCas0092_csc1gr5_CAS-I-D	unknown
NC_018870.1\|WP_015050960.1\|1906700_1908098_+\|ferrous-iron-transporter-B	unknown	unknown	gnl\|CDD\|223447
NC_018870.1\|WP_015050974.1\|1927999_1928941_-\|CRISPR-associated-protein-Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	gnl\|CDD\|187840
NC_018870.1\|WP_015050959.1\|1905924_1906713_+\|50S-ribosome-binding-GTPase	unknown	unknown	gnl\|CDD\|376781
NC_018870.1\|WP_049886111.1\|1923779_1924733_-\|type-I-A-CRISPR-associated-protein-Cas4/Csa1	cas4	pfam06023_cas4_CAS-I	gnl\|CDD\|283640

Protein	Function_ID	Function_description	E-value
NC_018870.1\|WP_015050972.1\|1926825_1927182_-\|DUF4282-domain-containing-protein	gnl\|CDD\|379475	pfam14110, DUF4282, Domain of unknown function (DUF4282). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 93 and 155 amino acids in length. There is a single completely conserved residue E that may be functionally important.	1.45334e-16
NC_018870.1\|WP_148276000.1\|1909136_1910051_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.42413e-07
NC_018870.1\|WP_028990907.1\|1924732_1925311_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	1.65878e-27
NC_018870.1\|WP_148275896.1\|1905344_1905596_-\|CGGC-domain-containing-protein	gnl\|CDD\|198146	smart01078, CGGC, This putative domain contains a quite highly conserved sequence of CGGC in its central region. The domain has many conserved cysteines and histidines suggestive of a zinc binding function.	3.8673e-19
NC_018870.1\|WP_015050964.1\|1910569_1911832_-\|hypothetical-protein	gnl\|CDD\|224160	COG1239, ChlI, Mg-chelatase subunit ChlI [Coenzyme metabolism].	3.52453e-42
NC_018870.1\|WP_028990910.1\|1908329_1908992_-\|CoA-pyrophosphatase	gnl\|CDD\|239518	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative stress. CoAse has a conserved Nudix fold and requires a single divalent cation for catalysis. In addition to a signature Nudix motif G[X5]E[X7]REUXEEXGU, where U is Ile, Leu, or Val, CoAse contains an additional motif upstream called the NuCoA motif (LLTXT(SA)X3RX3GX3FPGG) which is postulated to be involved in CoA recognition. CoA plays a central role in lipid metabolism. It is involved in the initial steps of fatty acid sythesis in the cytosol, in the oxidation of fatty acids and the citric acid cycle in the mitochondria, and in the oxidation of long-chain fatty acids in peroxisomes. CoA has the important role of activating fatty acids for further modification into key biological signalling molecules.	6.85159e-31
NC_018870.1\|WP_015050970.1\|1925348_1925651_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	5.97384e-18
NC_018870.1\|WP_015050977.1\|1931722_1932487_-\|hypothetical-protein	gnl\|CDD\|193608	cd09641, Cas3''_I, CRISPR/Cas system-associated protein Cas3''. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; HD-like nuclease, specifically digesting double-stranded oligonucleotides and preferably cleaving at G:C pairs; signature gene for Type I.	7.20552e-09
NC_018870.1\|WP_028990906.1\|1925681_1926692_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	4.68447e-96
NC_018870.1\|WP_015050974.1\|1927999_1928941_-\|CRISPR-associated-protein-Csc2	gnl\|CDD\|187840	cd09709, Csc2_I-D, CRISPR/Cas system-associated protein Csc2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas7 ortholog; also known as Cse1 family.	8.28043e-06
NC_018870.1\|WP_015050958.1\|1905664_1905904_+\|ferrous-iron-transport-protein-A	gnl\|CDD\|377199	pfam04023, FeoA, FeoA domain. This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.	7.13502e-16
NC_018870.1\|WP_015050960.1\|1906700_1908098_+\|ferrous-iron-transporter-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	2.66784e-59
NC_018870.1\|WP_015050959.1\|1905924_1906713_+\|50S-ribosome-binding-GTPase	gnl\|CDD\|376781	pfam02421, FeoB_N, Ferrous iron transport protein B. Escherichia coli has an iron(II) transport system (feo) which may make an important contribution to the iron supply of the cell under anaerobic conditions. FeoB has been identified as part of this transport system. FeoB is a large 700-800 amino acid integral membrane protein. The N-terminus contains a P-loop motif suggesting that iron transport may be ATP dependent.	1.22621e-88
NC_018870.1\|WP_049886111.1\|1923779_1924733_-\|type-I-A-CRISPR-associated-protein-Cas4/Csa1	gnl\|CDD\|283640	pfam06023, Csa1, CRISPR-associated exonuclease Csa1. CRISPR (clustered regularly interspaced short palindromic repeats) elements and cas (CRISPR-associated) genes are widespread in Bacteria and Archaea. The CRISPR/Cas system operates as a defense mechanism against mobile genetic elements (i.e., viruses or plasmids). Csa1 is part of the archaeal subtype I-A system. Cas1 has not yet been enzymatically characterized.	1.15189e-84

>NC_018870.1|WP_015050967.1|1914094_1915081_-|hypothetical-protein
MTVLSEFFSTLQVGEPQMYENLVIFPLLGMELRDPGYLLLDEALVKGLLEVREIDESGSVNEVLVINKGETPVLLMDGEILSGAKQNRVVNISILVAPRVELKIPVSCVEQGRWRYVADGFTESRRFAYAFLRAKKSQQVAENIMSCGAFMANQGAIWEEIGRKQREMGAESPTGAVNEVYESHENRLRKYCDAFAPLENQVGVAVYINCHFLCLDAFDSPAVLNKMYTKMIESYALDALERLDWRGKEKPDKGAVNKLLERIARAGVDRYPSVGLGDSLRLKADGLGGFCLSLEDRVIHLAVFAAEEGRANSGSRLSSPGRRRRSHL
>NC_018870.1|WP_015050966.1|1913031_1914006_-|hypothetical-protein
MNESVNDREFSWNRGMEGSYGPEVEPDEKFRRPAGSRKWFFLALLFMCFASFTGLQIWGAGEFQKGIGGIEQEVRKLNERLRLLENTAGERKVMVFLNDVESLSRECQEKMQTMAELKQQWWFVLPFLKEETVAQELSNLQQELNEIVAVRPTIEAFSRRLIETDDRIAGVMDAIGAADAGGAIVELASFIEDSDVLRKDIERLQWPPALAPFKEAFLNALHERDAALNALLAALDSAAKASAFAEQAVGTYMMAWSFWDYQMVLNYLEASDEYSSQAEGYMAEFEFHTARYFKIRDRLIEFPTSEIETPAAAEEVGISNGIIR
>NC_018870.1|WP_015050964.1|1910569_1911832_-|hypothetical-protein
MKNYLQLTRHKGNAPLFLAVEMSLVSTLQGRPLHIHAEGLRGTGKTTIMRSVTQILPKITRIKGCLYNCDPERPHCPQHKNMTPEEIAALGTEQIPVPFLEISHSAKIGTVAGTIDLAKLTNPSRPEAALLPGIIPQAHRGIVFVDEINRLADTSPEITDVLLDAMGTKPGRVQIEETGLPVVEVPVAVSVWAASNPDEEPGPLAEIRRQLSDRFDLVIPMGRPTTPEEVVDILTTEEAKNDRELSEQERSQLEQLRKNLENIALHSDLTMPDYLTTFLANLYINFNIESLRALEAIRQAALLHCALRKRSQVMISDIMAVLPLALYHRVSPATLTEIMNTVNNRMVGNEKEKENGKRSAQGRQLPPIFHNKKGDKRQMSEDSPPEKARLLRDLPENGIIRKESEIQTMIEKLTPRTWGG
>NC_018870.1|WP_148276000.1|1909136_1910051_-|CPBP-family-intramembrane-metalloprotease
MLKRALTFTVLTLALSYAFAAFLYFGVHLRWNTLLAQFAGMAYMFIPTLVVVGLQRFAYREPVVSTMGICWRPNKWWVAAWLFPPALAFAALGVSLLLPGVTYDPSLSGMFQRYQHVFPPETVAEMQRQMEAMPLHPLWIALVQGLIAGATINAVFAFGEELGWRGFLLRETAGLGFWRANLLIGFIWGVWHAPLILQGHNYPQHPVAGVFMMIIWCLLLSPLFGFLRLAGKSVLAAALVHGALNGTAALAIMVIAGGSDLTVGVTGLAGFVALAAANVGLWAYERFRERGFLDRLLEQAARPC
>NC_018870.1|WP_028990910.1|1908329_1908992_-|CoA-pyrophosphatase
MTGEQLMQLQHRLSDRPGLLGREDHLNTAVLMLLMPVDGEYHFVLEERQLEIPQGGEICFPGGAFDPEQDADTVQTAIRETVEELGIAKERLELLGALGTLYTSMGAIVDAYVGVCRLRGLDELRINTSEVKSAFTIPVSRFENTSPEEYRALVRVHPTYTEENTGQVRILFPSAELGLPKRYSRPWGSRTHRILVYRMGPRIVWGVTARLIYELLRRMR
>NC_018870.1|WP_015050961.1|1908075_1908285_-|hypothetical-protein
MRKSVLYLFWGGLLGALLGVVITVLVFAVVSLREAVYSWLGYYMTYFPAFVIIGGGLLGVVAVKALRGR
>NC_018870.1|WP_015050960.1|1906700_1908098_+|ferrous-iron-transporter-B
MGSLTTPLSSLLAEIDKEISPARRQEIRDSIVGSIYSHAEAIAARVVHYQERKMRWDEKIDDVLTSRLLGVPVMLALLGCILWLTVIGANYPSQALAAGLFWLEERLTALFLSAGAPAWLHGVLVLGMYRTLAWVVSVMLPPMAIFFPLFTLLEDLGYLPRVAFNLDRYFKKACAHGKQALTMCMGFGCNAAGVTSCRIIESPRERLIAILTNVFVPCNGRFPTLIALSLVFMGGAAATPFRTAAATATVVALVLLGVAVTLLMSWVLSRTILKGIPSFFTLELPPYRKPQVGRLLVRSLLDRTIFVLMRAVVMAAPAGAFTWILANTHIGSLNMISHLTGLLDPFGRLLGMDGVIILAFILGLPANEIVLPIMIMCYVSAGTMLELDSLQALQALLVDNGWTRLTALSVMLFSLLHYPCGTTLLTIHKETNSLKWTVLAALIPLTVAALTTFLMAQLATVLARL
>NC_018870.1|WP_015050959.1|1905924_1906713_+|50S-ribosome-binding-GTPase
MGLTFLSSGSNAPIKPSRPKPLPRRPLIALAGNPNTGKSTLFNALTGLRQHTGNWPGKTVLKATGTYYYRDKKFLLVDLPGTYSLLAKSADEEVARDFICFGHPDAIVVVTDATSLERNLNLVLQVMEISPQVVVCVNLMDEARRRKMRVDVEALSRELGVPCIPTAARNGVGLEELKEAIYNVATGKITPSPRLVTYAPEVEQAAAELAAQIRPYLPRRVNHRWVALRLLEGDYSIVEAICGHQDEESEKAARREVAAWAR
>NC_018870.1|WP_015050958.1|1905664_1905904_+|ferrous-iron-transport-protein-A
MPGKLLPLSQLPNGETGRVAHLAVDGLIRRHLMDLGLVIGSHVVAVRRSPSGDPTAFNIRGAIIALRNEDAGRILVHID
>NC_018870.1|WP_148275896.1|1905344_1905596_-|CGGC-domain-containing-protein
MYSKIYGVAVLQVPVRRRPLRGFPGPRQRGRRLVEKLLPHGLNVVHLSSCMMLEDDYPRCPHKEEIKRIIEKKGVRVVEGTHH
>NC_018870.1|WP_049886111.1|1923779_1924733_-|type-I-A-CRISPR-associated-protein-Cas4/Csa1
MYFLSDDERKQLLRYYLPKARELGVVDELRGWNWHQPPLEPVYGSVLALYEVAGKYCPSGRDVFLRRVQGIKGEPNSAMIQGMVLHEVLADLLVTAKRAIYLHGTEKYRAICEELEKYIPEKTSHFAGLTDSEAADLSRKVEILCSFEKARVLSRLQEVLTRYPYIGEDSLANLTIPVVVEQKLNGAFLGLSGNLSTDAFIFYEPMILDLKFGEPRDFHRLGTTGYALVMEAIYEFPVNLGCIIYGEFRGDRLIVKRDIHIISDELRQWFIEERDEKARFVTEEIDPGLAEDCPATCPFYHVCCAEDGSELLTSSIP
>NC_018870.1|WP_028990907.1|1924732_1925311_-|CRISPR-associated-protein-Cas4
MMEPILKVSDIKQYLYCPRIIYFTYVLPVEKRATPKMEIGKEEHLKTARLEGRRRLRSYGFEEGKRFFNVYLFSSRLGLEGVLDMYVAVSRGSFPVDFKNTYRPAVNHKYQLLAYTLLLEDHLRQPVRGGFIYLIPSRHTVYIEATPEARLYTKRLMGAIRSLIRREHFPAVSRSRGRCADCEYKNYCGDVG
>NC_018870.1|WP_015050970.1|1925348_1925651_-|CRISPR-associated-endonuclease-Cas2
MKTLVVYDIPDDRIRTKTFETCKDYGLVHIQYSAFFGELNHNRRQELQQRLYRVLGGKEGKILICPICDKDLSLILEVAVPETDSLSRKLAGLQKGPLVI
>NC_018870.1|WP_028990906.1|1925681_1926692_-|CRISPR-associated-endonuclease-Cas1
MSEIFIVNFGTTLGKKSERLVIKEQGKVIGEIPFQDVTCLTIASRGVSLSSDVVLECIQHGIQINFLTPSGKPYAKITSPQLSGTVLTRREQILAYKDGRGLALALAFIDGKLRNQVNVLKYFGKYRRASDAALYQELVTRIAAIEEIKKELEGISDGTVEEARGNIFSIEGRAAQAYWEGVGLLLGQRIEFAGRERRGAEDPVNSALNYGYGILYSQVWGAVMLAGLEPFAGFLHTDRPGKPSLVLDLTEEFRACIVDRTVIGMILRGTAINQNEGSLTEETRRELARRILERLDGEENYEGKKYKMRSIVQRQARRVAAYLRGEGKYKPFIAGW
>NC_018870.1|WP_015050972.1|1926825_1927182_-|DUF4282-domain-containing-protein
MTEKSFWPRLFDFSFSSFVTLKIIPILYCLWIAIGVIGALGMLATGGMRTMQFGWWLGNFLFSLIWAVVFFFLWVIGGRVWMETIIVLFRIAENTSALVQAGRGWWSESWEGAKDTLV
>NC_018870.1|WP_015050973.1|1927203_1927986_-|hypothetical-protein
MLYARAITLRNCGRFTVVASDFGSDYRTHTHVTSEALYASLTRGATWRPRLIDLRNDPDAFTQAYDVAAMPVWFLPGIFMAEGSHRLPDAFLDTTAFNVVHEFYPSTGRSYMFKKGSLEAKDRPYYVPTYGTIQAIKPDQRLVTYGLSAKPELLESFAEGQTFLLGKKRTMFQIVGLSEVVEGTVKCGKCITGWLELHANHSHYWQNFESFEVLATTLRYIILRGTTRKKAGYMEFAFSDGSGLCVPDFYFELLRQERIL
>NC_018870.1|WP_015050974.1|1927999_1928941_-|CRISPR-associated-protein-Csc2
MSQIELFVDQMASVSVLVPRVVNKRRVAQPIYTRRVVTIVGVKTVKTRFLPVSHEGYGNESYVDKLELLGKTRAEFISRKLKGIERRAHMSLFRELVEQKTNSSWQDYFTAKFDKECTIPDSLCIACWNCSLFGGLEAGKGATFSRIRYFDTYSVEDAVDCIAMEGSEEGMGIGNQVYEDVNKGRGAETYHLYEYVKAGTRFPFITIIESPTLLDVAGYLHTVRRADEHGYGKYSANHGKFDTEFLVVATGYPRFSVLDMLKWADEGTLDSRFEEGKVQFDDLNGSVSLFGKEIEALAGKLTEAFEEYFAALG
>NC_018870.1|WP_015050975.1|1928996_1929623_-|hypothetical-protein
MPRQVNTTEMDEFCQLLFRTLDRLGGDLLPLFLSERPTAYEKYPRLLLGCIRYYDNVEAGFEEWKSKVLRDASDYRREQEFPELLALKKWLLDHRGLFEGRKDNLNHLKRSLYARAYEYLYPRRLLTGAYAEANRGNPDALEEDAIRANFRRVVQPHIAKLAQVYGEGERLQTIVTEAEEFLLANRQRYRWKLREMEAMETPEEAAGN
>NC_018870.1|WP_015050976.1|1929665_1931726_-|hypothetical-protein
MNGNPFTFVVQAAEETLNSWSLGNAVGSHTVASLVADGAAYWEQTLSDGSHLAVIRLYSPVVRREEVFLGNVLLNDFLSKALIRAVERNGLGRIRLLANDLESHYYLYHGEVVLDQIAECFRQEILDSLPDLYFGDEDQARGIYGDIGRMLTFYKSNIEPFPAFAVPRDLLPGLLAKINRRLRELVEEEETNINIILAILSFFYAKDGTEMQSFYAFLCRAMNEGLLPTAPVRGAFALGPGDIFDKTVFTERKNAQVIDRAQLKIAIDGFLSNVQQQIDNGAAETVAANLARKMPALSLAQAASVLVQGVQLGFLPIWEIGCKAAAERKMPCRFCSADAAIIAEKNITGGFGAGRFYNQSPKLRPFEEALCVRCGISSYLVIKLLGMHIARPQPKAKDFPVPKQFNIIFHYGRHGEADARRLAAVIDYLFERIGTFQQRAREDKRPFSVEYMREELIRWERERQDMDPCSAGEIPSAEEAFAALIADDTVAPGLETLGQMRTDVKAQVLPLGVGDYRLLAFILPQLQPGREEALDFVQRRFSKSRLAAFTLLALLRKLCGCDGPYYFQSVPTLAPGGFDTNTFYVQGKAENADDVIRHFSAIVNFARRVVKWREGHSLLADWILLAERLEEDPLGTFSEVLRDSPLRVGDDLREARYRRLSNEFAKGMGVVDGTEYLKLIEQLKQL
>NC_018870.1|WP_015050977.1|1931722_1932487_-|hypothetical-protein
MLIDKYKATLGKSTGRQTLYDHSLSCVEVALRVARLAGEAPGPRLDRLIFATFVHDVGKLDPDFQAMLNAAASAQSLPGKRVKHEASTFDYDHPRMVEESKEAIRQELRGACGYDLDLANLEGTAMDHIWAFAVTHHGFFHLSYEREKAGTLRPLIRRQWTSFYPNEERRITLVDLLFTYHPLGGLVMIGDLVASYCHEQGQDYRPFFNQASSLGEVFAYLTENADEIEAGLKRYDPRNYGLKETLKLIGGGLR

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Crispr_ID: NC_018870_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018870_4

2204611-2211549

Unclear

Consensus_repeat	Method
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	PILER-CR
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CRISPRCasFinder
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CRT

104 spacers

Cas14b_CAS-V-F

The CRISPR arrays of NC_018870_4

>merge|NC_018870|4|2204611-2211549|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATTCCTCATAGGTAGGCTGGAAACGGTGGTAAGTTGGGCTGGGCCTTTGTGGGATAGTGCGTTTCAATTCCTCATAGGTAGGCTGGAAACCTTTTGCGGAGCTTCCTATGAGTGGGCCATATCCGGGTTTCAATTCCTCATAGGTAGGCTGGAAACACAGGAACCATTTCGTCCGACATGGTCTCTACCTCCGTTTCAATTCCTCATAGGTAGGCTGGAAACGATCCCCCGCCCTCCGCTGCAGGCGGTGAACAGTGTGTTTCAATTCCTCATAGGTAGGCTGGAAACCAGAGAAAATCAGTAAAATCAAGGATTGACGGGGCTTTGTTTCAATTCCTCATAGGTAGGCTGGAAACTCTTAATTACTAGGCGTTGCCGCTGTCACAACGCCGGTTTCAATTCCTCATAGGTAGGCTGGAAACCAAGTTGAGCCTGCTGGTACGCCGTCATATTCTGAGTTTCAATTCCTCATAGGTAGGCTGGAAACCCGGCAACAGGAAGCAGAAATCAAACCGGGGGAAAAAGGTTTCAATTCCTCATAGGTAGGCTGGAAACTGCCATCAAGCAGGGCCAGGACGCATGGACGACCGGGGTTTCAATTCCTCATAGGTAGGCTGGAAACCGCGGAGCGAGTACGAGTTGAGAACCTATGTGGGCGTTTCAATTCCTCATAGGTAGGCTGGAAACTCGGCACCACGAACCCGGATTCGCCTTATCACTGGCGTTTCAATTCCTCATAGGTAGGCTGGAAACTCAACCTGGCGGTGGCGAAGAAGCTTGCCGGCTATCGTTTCAATTCCTCATAGGTAGGCTGGAAACGGTAGATGGGTGACGGTCAGCACCGGATAGGGCGATGGTTTCAATTCCTCATAGGTAGGCTGGAAACCCGGCGTGGCCGGACACCGTGCCGGTTTTCTGTTCGGGTTTCAATTCCTCATAGGTAGGCTGGAAACGAGGGGATGAACCGGTTGGCAATCCGTAAAAGCTTGAGTTTCAATTCCTCATAGGTAGGCTGGAAACTAAATCAGCGCTTACTGGTAGACGCCTTTCTGAAAGCCAGTTTCAATTCCTCATAGGTAGGCTGGAAACATCCGCCGCAGCTACGAGGAGGAGGTGTGATGATGCGGGGTTTCAATTCCTCATAGGTAGGCTGGAAACCCTAAACGGTGATAGTTTATGAGGGTACGGATACTGCGGTTTCAATTCCTCATAGGTAGGCTGGAAACTTGTCCACGCACCCGGAGGCCGTGCATGTCCTCGTAAGCTTGTTTCAATTCCTCATAGGTAGGCTGGAAACTACTATTGCTGGTATTATTCTTAAACACTGGAAAGGTTTCAATTCCTCATAGGTAGGCTGGAAACCGCGGAGCGAGTACGAGTTGAGAACCTATGTGGGCGTTTCAATTCCTCATAGGTAGGCTGGAAACTCGAGGAAGGCGGATGGCGCTGGGTTAGGGATGAGAGTTTCAATTCCTCATAGGTAGGCTGGAAACTCATTGAAAACGCCGTGGCTTTCTTGATGCTTTCTGGGTTTCAATTCCTCATAGGTAGGCTGGAAACGGGCAGGTGGCCCTGACAAAGAGGACATCGACTGGGGGTTTCAATTCCTCATAGGTAGGCTGGAAACGGATGGCAGAAGTATACAAGCAACCGGCAGTTGCGGGTTTCAATTCCTCATAGGTAGGCTGGAAACCTGCATAGCCTTTTTCCACTCCGGCTCCAGCACTTCAGGTTTCAATTCCTCATAGGTAGGCTGGAAACCCAGGGTTCTTTGAGAACCTGGGGAGCATAGAGCCAGTTTCAATTCCTCATAGGTAGGCTGGAAACCCACTAGGTACTGCCCGAAACTTTTTGCTTCAGCTTGTTTCAATTCCTCATAGGTAGGCTGGAAACAAGCTCAGTTGCGAACGTATGACGGAGAGAATGCGGAGTTTCAATTCCTCATAGGTAGGCTGGAAACCTTATGTGCCGGGAGGTGGTGGCCGGTGGCGGAAGTGTTTCAATTCCTCATAGGTAGGCTGGAAACTTCAGTCCGGCCAGGAATTCCTTCCATCCTACACTGTGTTTCAATTCCTCATAGGTAGGCTGGAAACTCACCAGGTACTTCTTCGTGCCGCTCTCGCCGCCCTGTTTCAATTCCTCATAGGTAGGCTGGAAACCTGGATTGGCGAGGGCGAGGAAAAACCGGAGACCGGCGGTTTCAATTCCTCATAGGTAGGCTGGAAACTGTTGAAACGGCTGCTCTGGAAGCACTTGAGATGATGTTTCAATTCCTCATAGGTAGGCTGGAAACGTTAGGAAACTTTATGGGGGGGGTGTCTGATGCCTAGTTTCAATTCCTCATAGGTAGGCTGGAAACGGATCCGGAAGTTAGTATCGGTGGTTAGGGGAATGGGTTTCAATTCCTCATAGGTAGGCTGGAAACACATGGGTAAGGTCTGGGCATTCGGTCCTGCTTTACTGTTTCAATTCCTCATAGGTAGGCTGGAAACTAATTGAGTACCTGCAGGCTATGGAGAACGGGGAAGGTTTCAATTCCTCATAGGTAGGCTGGAAACTCCTGAACATCTGGCCAGAAGCGCTGACTTTATGATTGTTTCAATTCCTCATAGGTAGGCTGGAAACTTGCCAAAAACCTGCTTTCAGGCAAAGCTGATTACCAGTTTCAATTCCTCATAGGTAGGCTGGAAACCCAGGGTTCTTTGAGAACCTGGGGAGCATAGAGCCAGTTTCAATTCCTCATAGGTAGGCTGGAAACCGCTACTCGTCCTGCTCCTGCATGGACGAGGACGAGGTTTCAATTCCTCATAGGTAGGCTGGAAACATATCTCATTTCTGGGTCTCTGGTGAGGCGACCGATGTTTCAATTCCTCATAGGTAGGCTGGAAACCGTATAGGAGATAGTGCCGTCTCCGCCCTCCGCGCTAGTTTCAATTCCTCATAGGTAGGCTGGAAACTTGAACGGATAGGTGGAGATACGCTTCCCCCGATTGGGTTTCAATTCCTCATAGGTAGGCTGGAAACGTTTAAAATGCGAAGAAAAGGAGGCCGAGCTTATGAGTTTCAATTCCTCATAGGTAGGCTGGAAACCCAAACAACCTAATCAGAAGTTACTCGATGAGGGTGTTTCAATTCCTCATAGGTAGGCTGGAAACTACTGATGAAATGCTAGATTATTGGGCATCAAAACGCATGTTTCAATTCCTCATAGGTAGGCTGGAAACTTGGATAAGAAGTAGGGAAATAGTTTTAAGGATAGGGTTTCAATTCCTCATAGGTAGGCTGGAAACTCTCGAAAAAATCAGCCACTTTTTCAACAGGAAACGGTTTCAATTCCTCATAGGTAGGCTGGAAACTGCCGAAATGGATTTAGACCATAACCTGGTTATCACGTTTCAATTCCTCATAGGTAGGCTGGAAACGCCCAGATCGGAACCTGTCCCTCACCCCGGCTTGTGTTTCAATTCCTCATAGGTAGGCTGGAAACAGGGGTATTCTCCTGACGTTCTCGAGGAGGAGACTACGCGTTTCAATTCCTCATAGGTAGGCTGGAAACCAAAAAGGGGGATCGCAGACTATTCATAAAAAAACAAGTTTCAATTCCTCATAGGTAGGCTGGAAACTTCAACCTCGCGCCGCGCCTTCTCCTGCGCGGCCTGTTTCAATTCCTCATAGGTAGGCTGGAAACAGGCGGGAACTGTATCGTAGATATTTCTAGAGCCAGTTTCAATTCCTCATAGGTAGGCTGGAAACAAGGCGTTGACTATGCGGAGGTGGAGGAGTACCTGCTGTTTCAATTCCTCATAGGTAGGCTGGAAACGCCGGTAACCTCTTGAGCGAGTGCCTTGTTACCTTTGTTTCAATTCCTCATAGGTAGGCTGGAAACTAATTTGCAAACCCAAATGATGCTACCGTTTTAACCGTTTCAATTCCTCATAGGTAGGCTGGAAACCGGGATTTTGTGAGATGTGGACCCTGGGAGGGCCTGAGTTTCAATTCCTCATAGGTAGGCTGGAAACCGATAAGTTGATTTTTGAGTTTGAGGACCCAGTACCAAGTTTCAATTCCTCATAGGTAGGCTGGAAACGCCAAATGGAATACTTTCCGCATCGCTGGTCCTCCGTTTCAATTCCTCATAGGTAGGCTGGAAACCCGTATTAAGGGCACGCTCATAGTCCCGTGTGGCCAGTTTCAATTCCTCATAGGTAGGCTGGAAACTTTGTTCAAGTCCTTAAATTGCATCACACCACCACGTTTCAATTCCTCATAGGTAGGCTGGAAACCTTGGATTAAGACGAAAACAAAAAGCCCCGGCCTCTGTTTCAATTCCTCATAGGTAGGCTGGAAACGACCGGCGGCGAGGGGGTACCGGTGAAGAATGCGATGTTTCAATTCCTCATAGGTAGGCTGGAAACATGAGAATTTGCCCGGTAGCATCGGAAACCAGTGCTTGTTTCAATTCCTCATAGGTAGGCTGGAAACCAGCGTTCTTCTTCTCCCACTCTACCCGGTACGCCTCGTTTCAATTCCTCATAGGTAGGCTGGAAACTTCTGGGCCTTTTCCATCACGCTCGCGAATTTCTCGTTTCAATTCCTCATAGGTAGGCTGGAAACGGCCGTAGCAACGAAAAACTGGTCAAGGACTTGATCGTTTCAATTCCTCATAGGTAGGCTGGAAACAATTACACTTGAGGTTGACGAAGAAGATTTATTCCAAATGTTTCAATTCCTCATAGGTAGGCTGGAAACTTGATCAGAATATCGCCGAAGTCAAGCACACCGGGTTTCAATTCCTCATAGGTAGGCTGGAAACGAGCACGTCCTGGCCGCCGCCGGAAACAGATACGTTGTTTCAATTCCTCATAGGTAGGCTGGAAACTTCTCGGCCGGCAAAATTTCGATTTTACCCCTATCATGTTTCAATTCCTCATAGGTAGGCTGGAAACGCAGGTCGCAGGGTGACCGACGGCCAGCTTTTGTCGGTTTCAATTCCTCATAGGTAGGCTGGAAACGTCTTCTTCCAGATCTGCCGTGCCTCATCATCTAGCGTTTCAATTCCTCATAGGTAGGCTGGAAACGTGTTGAAATTCCTGGACGCCTTCTACTTCGGCGACGTTTCAATTCCTCATAGGTAGGCTGGAAACTAGCGGAAAGTGGACTGGTTGCAATTTCGATTGGCTGAGTTTCAATTCCTCATAGGTAGGCTGGAAACCATTATAATTCTTGCGTAGCTTTGCGCCGCCTTGACAGTTTCAATTCCTCATAGGTAGGCTGGAAACGTTACGGCCCCAATTTTGAGCCGTTTTACACGGATTTGTTTCAATTCCTCATAGGTAGGCTGGAAACGTGGGTCAAGGCCAACCCGGTTCTGCAGGAGGACAACGTTTCAATTCCTCATAGGTAGGCTGGAAACGCGTACGTGCAGTCATAGTCATCATCATAATCAGTGTTTCAATTCCTCATAGGTAGGCTGGAAACGGTGTAATGTGAGAATAGGTTTAGATTATAGGATTAGTTTCAATTCCTCATAGGTAGGCTGGAAACCCTGCAAACCTTCTACCACCGGCACCTCATCACTGGGTTTCAATTCCTCATAGGTAGGCTGGAAACAAACAAACTGCTCTATTTTCTTTTCTTCCATTTTATGTTTCAATTCCTCATAGGTAGGCTGGAAACGGCACTTGGCACATGATCAACGTCAAGCCCGACATCGGTTTCAATTCCTCATAGGTAGGCTGGAAACGAAGGGGAGGCTGAATTATATGACGCTGGATGAATATGTTTCAATTCCTCATAGGTAGGCTGGAAACCCGGGATTGTGGACTGTTGGATTTTATGACCCAAATGGGTTTCAATTCCTCATAGGTAGGCTGGAAACTATATGTCAGTAGTATTATCGGTGCGGCCAAGAAGAGTTTCAATTCCTCATAGGTAGGCTGGAAACGCAACACGCCCTAGGTACATAAAATATCTACATTTTTGTTTCAATTCCTCATAGGTAGGCTGGAAACCGGTTATGATGCCTGGCTGGTCGAGACCGAGGGGGGTTTCAATTCCTCATAGGTAGGCTGGAAACTCCACTATCCGTGTAAGAATGTTGAGATGTGCTGCGTTTCAATTCCTCATAGGTAGGCTGGAAACACAGTCATACCTAGACATACTACACGGGCGCATCTGTTTCAATTCCTCATAGGTAGGCTGGAAACGCAATCATCCAAACATCAATATGGTGCTAACAGACTGTTTCAATTCCTCATAGGTAGGCTGGAAACTAGAAAGCGACCTGGTGCTGTTGAGGTATCTGAAGGGTTTCAATTCCTCATAGGTAGGCTGGAAACCCTCCCAGTATAGCTCGGCTACTGCGATGAAATCACGTTTCAATTCCTCATAGGTAGGCTGGAAACTTTCCCACAAAGATAAAGCTGAGCGGGAAATATTGTTTCAATTCCTCATAGGTAGGCTGGAAACTCCCACCCCTTTTAATAATAGGGAGCCTGCTTTTCCTGTTTCAATTCCTCATAGGTAGGCTGGAAACCCTTACAGGTATCGCATTAACCTTCCTCAAACCCTCGTTTCAATTCCTCATAGGTAGGCTGGAAACGCTCTTCGGATTTGACCATCCAGTCCCTACTGTTGAAGTTTCAATTCCTCATAGGTAGGCTGGAAACTTAGGTAAAAAGGTGGTCTTCTAGTTCCAGAAATTCGTTTCAATTCCTCATAGGTAGGCTGGAAACGTGCGAGGTAAATGTTAGGAGCAGATTGATAGTTTTGTTTCAATTCCTCATAGGTAGGCTGGAAACATGCTCCTAGGTATGGATGTGGTGAAAGATGACATGGTTTCAATTCCTCATAGGTAGGCTGGAAACTTGCACCTCCCACCTTGCGGCCACGCCGTTGGCATCGGTTTCAATTCCTCATAGGTAGGCTGGAAAC

>NC_018870|4|3|2204611-2211549|PILER-CR
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGTGGTAAGTTGGGCTGGGCCTTTGTGGGATAGTGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CTTTTGCGGAGCTTCCTATGAGTGGGCCATATCCGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ACAGGAACCATTTCGTCCGACATGGTCTCTACCTCC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GATCCCCCGCCCTCCGCTGCAGGCGGTGAACAGTGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CAGAGAAAATCAGTAAAATCAAGGATTGACGGGGCTTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCTTAATTACTAGGCGTTGCCGCTGTCACAACGCCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CAAGTTGAGCCTGCTGGTACGCCGTCATATTCTGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCGGCAACAGGAAGCAGAAATCAAACCGGGGGAAAAAG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TGCCATCAAGCAGGGCCAGGACGCATGGACGACCGGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGCGGAGCGAGTACGAGTTGAGAACCTATGTGGGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCGGCACCACGAACCCGGATTCGCCTTATCACTGGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCAACCTGGCGGTGGCGAAGAAGCTTGCCGGCTATC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGTAGATGGGTGACGGTCAGCACCGGATAGGGCGATG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCGGCGTGGCCGGACACCGTGCCGGTTTTCTGTTCGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GAGGGGATGAACCGGTTGGCAATCCGTAAAAGCTTGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TAAATCAGCGCTTACTGGTAGACGCCTTTCTGAAAGCCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ATCCGCCGCAGCTACGAGGAGGAGGTGTGATGATGCGGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCTAAACGGTGATAGTTTATGAGGGTACGGATACTGCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGTCCACGCACCCGGAGGCCGTGCATGTCCTCGTAAGCTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TACTATTGCTGGTATTATTCTTAAACACTGGAAAG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGCGGAGCGAGTACGAGTTGAGAACCTATGTGGGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCGAGGAAGGCGGATGGCGCTGGGTTAGGGATGAGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCATTGAAAACGCCGTGGCTTTCTTGATGCTTTCTGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGGCAGGTGGCCCTGACAAAGAGGACATCGACTGGGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGATGGCAGAAGTATACAAGCAACCGGCAGTTGCGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CTGCATAGCCTTTTTCCACTCCGGCTCCAGCACTTCAG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCAGGGTTCTTTGAGAACCTGGGGAGCATAGAGCCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCACTAGGTACTGCCCGAAACTTTTTGCTTCAGCTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AAGCTCAGTTGCGAACGTATGACGGAGAGAATGCGGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CTTATGTGCCGGGAGGTGGTGGCCGGTGGCGGAAGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTCAGTCCGGCCAGGAATTCCTTCCATCCTACACTGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCACCAGGTACTTCTTCGTGCCGCTCTCGCCGCCCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CTGGATTGGCGAGGGCGAGGAAAAACCGGAGACCGGCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TGTTGAAACGGCTGCTCTGGAAGCACTTGAGATGAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTTAGGAAACTTTATGGGGGGGGTGTCTGATGCCTA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGATCCGGAAGTTAGTATCGGTGGTTAGGGGAATGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ACATGGGTAAGGTCTGGGCATTCGGTCCTGCTTTACT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TAATTGAGTACCTGCAGGCTATGGAGAACGGGGAAG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCCTGAACATCTGGCCAGAAGCGCTGACTTTATGATT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGCCAAAAACCTGCTTTCAGGCAAAGCTGATTACCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCAGGGTTCTTTGAGAACCTGGGGAGCATAGAGCCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGCTACTCGTCCTGCTCCTGCATGGACGAGGACGAG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ATATCTCATTTCTGGGTCTCTGGTGAGGCGACCGAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGTATAGGAGATAGTGCCGTCTCCGCCCTCCGCGCTA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGAACGGATAGGTGGAGATACGCTTCCCCCGATTGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTTTAAAATGCGAAGAAAAGGAGGCCGAGCTTATGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCAAACAACCTAATCAGAAGTTACTCGATGAGGGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TACTGATGAAATGCTAGATTATTGGGCATCAAAACGCAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGGATAAGAAGTAGGGAAATAGTTTTAAGGATAGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCTCGAAAAAATCAGCCACTTTTTCAACAGGAAACG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TGCCGAAATGGATTTAGACCATAACCTGGTTATCAC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCCCAGATCGGAACCTGTCCCTCACCCCGGCTTGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AGGGGTATTCTCCTGACGTTCTCGAGGAGGAGACTACGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CAAAAAGGGGGATCGCAGACTATTCATAAAAAAACAA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTCAACCTCGCGCCGCGCCTTCTCCTGCGCGGCCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AGGCGGGAACTGTATCGTAGATATTTCTAGAGCCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AAGGCGTTGACTATGCGGAGGTGGAGGAGTACCTGCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCCGGTAACCTCTTGAGCGAGTGCCTTGTTACCTTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TAATTTGCAAACCCAAATGATGCTACCGTTTTAACC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGGGATTTTGTGAGATGTGGACCCTGGGAGGGCCTGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGATAAGTTGATTTTTGAGTTTGAGGACCCAGTACCAA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCCAAATGGAATACTTTCCGCATCGCTGGTCCTCC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCGTATTAAGGGCACGCTCATAGTCCCGTGTGGCCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTTGTTCAAGTCCTTAAATTGCATCACACCACCAC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CTTGGATTAAGACGAAAACAAAAAGCCCCGGCCTCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GACCGGCGGCGAGGGGGTACCGGTGAAGAATGCGAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ATGAGAATTTGCCCGGTAGCATCGGAAACCAGTGCTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CAGCGTTCTTCTTCTCCCACTCTACCCGGTACGCCTC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTCTGGGCCTTTTCCATCACGCTCGCGAATTTCTC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGCCGTAGCAACGAAAAACTGGTCAAGGACTTGATC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AATTACACTTGAGGTTGACGAAGAAGATTTATTCCAAAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGATCAGAATATCGCCGAAGTCAAGCACACCGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GAGCACGTCCTGGCCGCCGCCGGAAACAGATACGTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTCTCGGCCGGCAAAATTTCGATTTTACCCCTATCAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCAGGTCGCAGGGTGACCGACGGCCAGCTTTTGTCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTCTTCTTCCAGATCTGCCGTGCCTCATCATCTAGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTGTTGAAATTCCTGGACGCCTTCTACTTCGGCGAC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TAGCGGAAAGTGGACTGGTTGCAATTTCGATTGGCTGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CATTATAATTCTTGCGTAGCTTTGCGCCGCCTTGACA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTTACGGCCCCAATTTTGAGCCGTTTTACACGGATTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTGGGTCAAGGCCAACCCGGTTCTGCAGGAGGACAAC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCGTACGTGCAGTCATAGTCATCATCATAATCAGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGTGTAATGTGAGAATAGGTTTAGATTATAGGATTA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCTGCAAACCTTCTACCACCGGCACCTCATCACTGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AAACAAACTGCTCTATTTTCTTTTCTTCCATTTTAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGCACTTGGCACATGATCAACGTCAAGCCCGACATCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GAAGGGGAGGCTGAATTATATGACGCTGGATGAATAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCGGGATTGTGGACTGTTGGATTTTATGACCCAAATGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TATATGTCAGTAGTATTATCGGTGCGGCCAAGAAGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCAACACGCCCTAGGTACATAAAATATCTACATTTTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGGTTATGATGCCTGGCTGGTCGAGACCGAGGGGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCCACTATCCGTGTAAGAATGTTGAGATGTGCTGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ACAGTCATACCTAGACATACTACACGGGCGCATCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCAATCATCCAAACATCAATATGGTGCTAACAGACT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TAGAAAGCGACCTGGTGCTGTTGAGGTATCTGAAGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCTCCCAGTATAGCTCGGCTACTGCGATGAAATCAC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTTCCCACAAAGATAAAGCTGAGCGGGAAATATT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCCCACCCCTTTTAATAATAGGGAGCCTGCTTTTCCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCTTACAGGTATCGCATTAACCTTCCTCAAACCCTC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCTCTTCGGATTTGACCATCCAGTCCCTACTGTTGAA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTAGGTAAAAAGGTGGTCTTCTAGTTCCAGAAATTC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTGCGAGGTAAATGTTAGGAGCAGATTGATAGTTTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ATGCTCCTAGGTATGGATGTGGTGAAAGATGACATG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGCACCTCCCACCTTGCGGCCACGCCGTTGGCATCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC

>NC_018870|4|4|2204611-2211549|CRISPRCasFinder
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGTGGTAAGTTGGGCTGGGCCTTTGTGGGATAGTGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CTTTTGCGGAGCTTCCTATGAGTGGGCCATATCCGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ACAGGAACCATTTCGTCCGACATGGTCTCTACCTCC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GATCCCCCGCCCTCCGCTGCAGGCGGTGAACAGTGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CAGAGAAAATCAGTAAAATCAAGGATTGACGGGGCTTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCTTAATTACTAGGCGTTGCCGCTGTCACAACGCCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CAAGTTGAGCCTGCTGGTACGCCGTCATATTCTGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCGGCAACAGGAAGCAGAAATCAAACCGGGGGAAAAAG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TGCCATCAAGCAGGGCCAGGACGCATGGACGACCGGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGCGGAGCGAGTACGAGTTGAGAACCTATGTGGGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCGGCACCACGAACCCGGATTCGCCTTATCACTGGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCAACCTGGCGGTGGCGAAGAAGCTTGCCGGCTATC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGTAGATGGGTGACGGTCAGCACCGGATAGGGCGATG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCGGCGTGGCCGGACACCGTGCCGGTTTTCTGTTCGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GAGGGGATGAACCGGTTGGCAATCCGTAAAAGCTTGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TAAATCAGCGCTTACTGGTAGACGCCTTTCTGAAAGCCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ATCCGCCGCAGCTACGAGGAGGAGGTGTGATGATGCGGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCTAAACGGTGATAGTTTATGAGGGTACGGATACTGCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGTCCACGCACCCGGAGGCCGTGCATGTCCTCGTAAGCTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TACTATTGCTGGTATTATTCTTAAACACTGGAAAG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGCGGAGCGAGTACGAGTTGAGAACCTATGTGGGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCGAGGAAGGCGGATGGCGCTGGGTTAGGGATGAGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCATTGAAAACGCCGTGGCTTTCTTGATGCTTTCTGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGGCAGGTGGCCCTGACAAAGAGGACATCGACTGGGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGATGGCAGAAGTATACAAGCAACCGGCAGTTGCGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CTGCATAGCCTTTTTCCACTCCGGCTCCAGCACTTCAG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCAGGGTTCTTTGAGAACCTGGGGAGCATAGAGCCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCACTAGGTACTGCCCGAAACTTTTTGCTTCAGCTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AAGCTCAGTTGCGAACGTATGACGGAGAGAATGCGGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CTTATGTGCCGGGAGGTGGTGGCCGGTGGCGGAAGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTCAGTCCGGCCAGGAATTCCTTCCATCCTACACTGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCACCAGGTACTTCTTCGTGCCGCTCTCGCCGCCCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CTGGATTGGCGAGGGCGAGGAAAAACCGGAGACCGGCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TGTTGAAACGGCTGCTCTGGAAGCACTTGAGATGAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTTAGGAAACTTTATGGGGGGGGTGTCTGATGCCTA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGATCCGGAAGTTAGTATCGGTGGTTAGGGGAATGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ACATGGGTAAGGTCTGGGCATTCGGTCCTGCTTTACT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TAATTGAGTACCTGCAGGCTATGGAGAACGGGGAAG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCCTGAACATCTGGCCAGAAGCGCTGACTTTATGATT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGCCAAAAACCTGCTTTCAGGCAAAGCTGATTACCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCAGGGTTCTTTGAGAACCTGGGGAGCATAGAGCCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGCTACTCGTCCTGCTCCTGCATGGACGAGGACGAG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ATATCTCATTTCTGGGTCTCTGGTGAGGCGACCGAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGTATAGGAGATAGTGCCGTCTCCGCCCTCCGCGCTA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGAACGGATAGGTGGAGATACGCTTCCCCCGATTGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTTTAAAATGCGAAGAAAAGGAGGCCGAGCTTATGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCAAACAACCTAATCAGAAGTTACTCGATGAGGGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TACTGATGAAATGCTAGATTATTGGGCATCAAAACGCAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGGATAAGAAGTAGGGAAATAGTTTTAAGGATAGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCTCGAAAAAATCAGCCACTTTTTCAACAGGAAACG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TGCCGAAATGGATTTAGACCATAACCTGGTTATCAC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCCCAGATCGGAACCTGTCCCTCACCCCGGCTTGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AGGGGTATTCTCCTGACGTTCTCGAGGAGGAGACTACGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CAAAAAGGGGGATCGCAGACTATTCATAAAAAAACAA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTCAACCTCGCGCCGCGCCTTCTCCTGCGCGGCCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AGGCGGGAACTGTATCGTAGATATTTCTAGAGCCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AAGGCGTTGACTATGCGGAGGTGGAGGAGTACCTGCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCCGGTAACCTCTTGAGCGAGTGCCTTGTTACCTTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TAATTTGCAAACCCAAATGATGCTACCGTTTTAACC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGGGATTTTGTGAGATGTGGACCCTGGGAGGGCCTGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGATAAGTTGATTTTTGAGTTTGAGGACCCAGTACCAA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCCAAATGGAATACTTTCCGCATCGCTGGTCCTCC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCGTATTAAGGGCACGCTCATAGTCCCGTGTGGCCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTTGTTCAAGTCCTTAAATTGCATCACACCACCAC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CTTGGATTAAGACGAAAACAAAAAGCCCCGGCCTCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GACCGGCGGCGAGGGGGTACCGGTGAAGAATGCGAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ATGAGAATTTGCCCGGTAGCATCGGAAACCAGTGCTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CAGCGTTCTTCTTCTCCCACTCTACCCGGTACGCCTC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTCTGGGCCTTTTCCATCACGCTCGCGAATTTCTC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGCCGTAGCAACGAAAAACTGGTCAAGGACTTGATC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AATTACACTTGAGGTTGACGAAGAAGATTTATTCCAAAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGATCAGAATATCGCCGAAGTCAAGCACACCGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GAGCACGTCCTGGCCGCCGCCGGAAACAGATACGTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTCTCGGCCGGCAAAATTTCGATTTTACCCCTATCAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCAGGTCGCAGGGTGACCGACGGCCAGCTTTTGTCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTCTTCTTCCAGATCTGCCGTGCCTCATCATCTAGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTGTTGAAATTCCTGGACGCCTTCTACTTCGGCGAC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TAGCGGAAAGTGGACTGGTTGCAATTTCGATTGGCTGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CATTATAATTCTTGCGTAGCTTTGCGCCGCCTTGACA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTTACGGCCCCAATTTTGAGCCGTTTTACACGGATTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTGGGTCAAGGCCAACCCGGTTCTGCAGGAGGACAAC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCGTACGTGCAGTCATAGTCATCATCATAATCAGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGTGTAATGTGAGAATAGGTTTAGATTATAGGATTA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCTGCAAACCTTCTACCACCGGCACCTCATCACTGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AAACAAACTGCTCTATTTTCTTTTCTTCCATTTTAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGCACTTGGCACATGATCAACGTCAAGCCCGACATCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GAAGGGGAGGCTGAATTATATGACGCTGGATGAATAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCGGGATTGTGGACTGTTGGATTTTATGACCCAAATGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TATATGTCAGTAGTATTATCGGTGCGGCCAAGAAGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCAACACGCCCTAGGTACATAAAATATCTACATTTTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGGTTATGATGCCTGGCTGGTCGAGACCGAGGGGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCCACTATCCGTGTAAGAATGTTGAGATGTGCTGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ACAGTCATACCTAGACATACTACACGGGCGCATCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCAATCATCCAAACATCAATATGGTGCTAACAGACT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TAGAAAGCGACCTGGTGCTGTTGAGGTATCTGAAGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCTCCCAGTATAGCTCGGCTACTGCGATGAAATCAC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTTCCCACAAAGATAAAGCTGAGCGGGAAATATT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCCCACCCCTTTTAATAATAGGGAGCCTGCTTTTCCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCTTACAGGTATCGCATTAACCTTCCTCAAACCCTC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCTCTTCGGATTTGACCATCCAGTCCCTACTGTTGAA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTAGGTAAAAAGGTGGTCTTCTAGTTCCAGAAATTC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTGCGAGGTAAATGTTAGGAGCAGATTGATAGTTTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ATGCTCCTAGGTATGGATGTGGTGAAAGATGACATG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGCACCTCCCACCTTGCGGCCACGCCGTTGGCATCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC

>NC_018870|4|3|2204611-2211549|CRT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGTGGTAAGTTGGGCTGGGCCTTTGTGGGATAGTGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CTTTTGCGGAGCTTCCTATGAGTGGGCCATATCCGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ACAGGAACCATTTCGTCCGACATGGTCTCTACCTCC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GATCCCCCGCCCTCCGCTGCAGGCGGTGAACAGTGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CAGAGAAAATCAGTAAAATCAAGGATTGACGGGGCTTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCTTAATTACTAGGCGTTGCCGCTGTCACAACGCCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CAAGTTGAGCCTGCTGGTACGCCGTCATATTCTGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCGGCAACAGGAAGCAGAAATCAAACCGGGGGAAAAAG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TGCCATCAAGCAGGGCCAGGACGCATGGACGACCGGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGCGGAGCGAGTACGAGTTGAGAACCTATGTGGGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCGGCACCACGAACCCGGATTCGCCTTATCACTGGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCAACCTGGCGGTGGCGAAGAAGCTTGCCGGCTATC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGTAGATGGGTGACGGTCAGCACCGGATAGGGCGATG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCGGCGTGGCCGGACACCGTGCCGGTTTTCTGTTCGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GAGGGGATGAACCGGTTGGCAATCCGTAAAAGCTTGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TAAATCAGCGCTTACTGGTAGACGCCTTTCTGAAAGCCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ATCCGCCGCAGCTACGAGGAGGAGGTGTGATGATGCGGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCTAAACGGTGATAGTTTATGAGGGTACGGATACTGCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGTCCACGCACCCGGAGGCCGTGCATGTCCTCGTAAGCTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TACTATTGCTGGTATTATTCTTAAACACTGGAAAG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGCGGAGCGAGTACGAGTTGAGAACCTATGTGGGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCGAGGAAGGCGGATGGCGCTGGGTTAGGGATGAGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCATTGAAAACGCCGTGGCTTTCTTGATGCTTTCTGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGGCAGGTGGCCCTGACAAAGAGGACATCGACTGGGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGATGGCAGAAGTATACAAGCAACCGGCAGTTGCGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CTGCATAGCCTTTTTCCACTCCGGCTCCAGCACTTCAG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCAGGGTTCTTTGAGAACCTGGGGAGCATAGAGCCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCACTAGGTACTGCCCGAAACTTTTTGCTTCAGCTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AAGCTCAGTTGCGAACGTATGACGGAGAGAATGCGGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CTTATGTGCCGGGAGGTGGTGGCCGGTGGCGGAAGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTCAGTCCGGCCAGGAATTCCTTCCATCCTACACTGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCACCAGGTACTTCTTCGTGCCGCTCTCGCCGCCCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CTGGATTGGCGAGGGCGAGGAAAAACCGGAGACCGGCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TGTTGAAACGGCTGCTCTGGAAGCACTTGAGATGAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTTAGGAAACTTTATGGGGGGGGTGTCTGATGCCTA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGATCCGGAAGTTAGTATCGGTGGTTAGGGGAATGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ACATGGGTAAGGTCTGGGCATTCGGTCCTGCTTTACT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TAATTGAGTACCTGCAGGCTATGGAGAACGGGGAAG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCCTGAACATCTGGCCAGAAGCGCTGACTTTATGATT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGCCAAAAACCTGCTTTCAGGCAAAGCTGATTACCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCAGGGTTCTTTGAGAACCTGGGGAGCATAGAGCCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGCTACTCGTCCTGCTCCTGCATGGACGAGGACGAG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ATATCTCATTTCTGGGTCTCTGGTGAGGCGACCGAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGTATAGGAGATAGTGCCGTCTCCGCCCTCCGCGCTA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGAACGGATAGGTGGAGATACGCTTCCCCCGATTGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTTTAAAATGCGAAGAAAAGGAGGCCGAGCTTATGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCAAACAACCTAATCAGAAGTTACTCGATGAGGGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TACTGATGAAATGCTAGATTATTGGGCATCAAAACGCAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGGATAAGAAGTAGGGAAATAGTTTTAAGGATAGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCTCGAAAAAATCAGCCACTTTTTCAACAGGAAACG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TGCCGAAATGGATTTAGACCATAACCTGGTTATCAC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCCCAGATCGGAACCTGTCCCTCACCCCGGCTTGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AGGGGTATTCTCCTGACGTTCTCGAGGAGGAGACTACGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CAAAAAGGGGGATCGCAGACTATTCATAAAAAAACAA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTCAACCTCGCGCCGCGCCTTCTCCTGCGCGGCCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AGGCGGGAACTGTATCGTAGATATTTCTAGAGCCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AAGGCGTTGACTATGCGGAGGTGGAGGAGTACCTGCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCCGGTAACCTCTTGAGCGAGTGCCTTGTTACCTTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TAATTTGCAAACCCAAATGATGCTACCGTTTTAACC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGGGATTTTGTGAGATGTGGACCCTGGGAGGGCCTGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGATAAGTTGATTTTTGAGTTTGAGGACCCAGTACCAA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCCAAATGGAATACTTTCCGCATCGCTGGTCCTCC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCGTATTAAGGGCACGCTCATAGTCCCGTGTGGCCA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTTGTTCAAGTCCTTAAATTGCATCACACCACCAC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CTTGGATTAAGACGAAAACAAAAAGCCCCGGCCTCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GACCGGCGGCGAGGGGGTACCGGTGAAGAATGCGAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ATGAGAATTTGCCCGGTAGCATCGGAAACCAGTGCTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CAGCGTTCTTCTTCTCCCACTCTACCCGGTACGCCTC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTCTGGGCCTTTTCCATCACGCTCGCGAATTTCTC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGCCGTAGCAACGAAAAACTGGTCAAGGACTTGATC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AATTACACTTGAGGTTGACGAAGAAGATTTATTCCAAAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGATCAGAATATCGCCGAAGTCAAGCACACCGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GAGCACGTCCTGGCCGCCGCCGGAAACAGATACGTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTCTCGGCCGGCAAAATTTCGATTTTACCCCTATCAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCAGGTCGCAGGGTGACCGACGGCCAGCTTTTGTCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTCTTCTTCCAGATCTGCCGTGCCTCATCATCTAGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTGTTGAAATTCCTGGACGCCTTCTACTTCGGCGAC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TAGCGGAAAGTGGACTGGTTGCAATTTCGATTGGCTGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CATTATAATTCTTGCGTAGCTTTGCGCCGCCTTGACA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTTACGGCCCCAATTTTGAGCCGTTTTACACGGATTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTGGGTCAAGGCCAACCCGGTTCTGCAGGAGGACAAC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCGTACGTGCAGTCATAGTCATCATCATAATCAGT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGTGTAATGTGAGAATAGGTTTAGATTATAGGATTA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCTGCAAACCTTCTACCACCGGCACCTCATCACTGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	AAACAAACTGCTCTATTTTCTTTTCTTCCATTTTAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GGCACTTGGCACATGATCAACGTCAAGCCCGACATCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GAAGGGGAGGCTGAATTATATGACGCTGGATGAATAT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCGGGATTGTGGACTGTTGGATTTTATGACCCAAATGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TATATGTCAGTAGTATTATCGGTGCGGCCAAGAAGA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCAACACGCCCTAGGTACATAAAATATCTACATTTTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CGGTTATGATGCCTGGCTGGTCGAGACCGAGGGGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCCACTATCCGTGTAAGAATGTTGAGATGTGCTGC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ACAGTCATACCTAGACATACTACACGGGCGCATCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCAATCATCCAAACATCAATATGGTGCTAACAGACT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TAGAAAGCGACCTGGTGCTGTTGAGGTATCTGAAGG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCTCCCAGTATAGCTCGGCTACTGCGATGAAATCAC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTTCCCACAAAGATAAAGCTGAGCGGGAAATATT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TCCCACCCCTTTTAATAATAGGGAGCCTGCTTTTCCT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	CCTTACAGGTATCGCATTAACCTTCCTCAAACCCTC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GCTCTTCGGATTTGACCATCCAGTCCCTACTGTTGAA
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTAGGTAAAAAGGTGGTCTTCTAGTTCCAGAAATTC
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	GTGCGAGGTAAATGTTAGGAGCAGATTGATAGTTTT
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	ATGCTCCTAGGTATGGATGTGGTGAAAGATGACATG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC	TTGCACCTCCCACCTTGCGGCCACGCCGTTGGCATCG
GTTTCAATTCCTCATAGGTAGGCTGGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018870.1\|WP_015051252.1\|2218637_2218844_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224393
NC_018870.1\|WP_015051232.1\|2192325_2192508_+\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015051237.1\|2199699_2200098_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133384
NC_018870.1\|WP_015051238.1\|2200230_2200668_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380361
NC_018870.1\|WP_015051233.1\|2192652_2193525_+\|NAD(+)/NADH-kinase	unknown	unknown	gnl\|CDD\|223139
NC_018870.1\|WP_015051239.1\|2200687_2201218_-\|flavodoxin	unknown	unknown	gnl\|CDD\|180760
NC_018870.1\|WP_015051241.1\|2202147_2203353_-\|iron-containing-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|341466
NC_018870.1\|WP_015051235.1\|2194080_2195835_+\|NADH-quinone-oxidoreductase-subunit-NuoF	unknown	unknown	gnl\|CDD\|224806
NC_018870.1\|WP_015051186.1\|2213389_2213770_-\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	Cas14b_CAS-V-F	-	gnl\|CDD\|284650
NC_018870.1\|WP_015051249.1\|2215117_2215693_+\|manganese-catalase-family-protein	unknown	unknown	gnl\|CDD\|153117
NC_018870.1\|WP_015051251.1\|2218185_2218614_-\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015051250.1\|2216224_2217454_-\|multidrug-effflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340878
NC_018870.1\|WP_015051246.1\|2212673_2212898_+\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015051240.1\|2201259_2202123_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381359
NC_018870.1\|WP_015051253.1\|2219325_2219844_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|366166
NC_018870.1\|WP_015051245.1\|2212251_2212671_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372378
NC_018870.1\|WP_015051248.1\|2214587_2214824_-\|VanW-family-protein	unknown	unknown	gnl\|CDD\|377286
NC_018870.1\|WP_148276009.1\|2193574_2194084_+\|NADH-quinone-oxidoreductase-subunit-NuoE	unknown	unknown	gnl\|CDD\|376507
NC_018870.1\|WP_028990850.1\|2215756_2216146_-\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015051236.1\|2195852_2199329_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|139246

Protein	Function_ID	Function_description	E-value
NC_018870.1\|WP_015051252.1\|2218637_2218844_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	6.13238e-25
NC_018870.1\|WP_015051237.1\|2199699_2200098_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	1.79853e-50
NC_018870.1\|WP_015051238.1\|2200230_2200668_-\|cupin-domain-containing-protein	gnl\|CDD\|380361	cd02233, cupin_HNL-like, Granulicella tundricola hydroxynitrile lyase (GtHNL) and related proteins, cupin domain. This family includes archaeal, eukaryotic, and bacterial proteins homologous to hydroxynitrile lyase from Granulicella tundricola (GtHNL), a novel class of HNLs that does not show any sequence or structural similarity to any other HNL and does not contain conserved motifs typical of HNLs. HNLs comprise a diverse group of enzymes that vary in terms of their substrate specificity, enantioselectivity and the need for a co-factor. In plants, they catalyze the reversible cleavage of cyanohydrins, yielding HCN and aldehydes or ketones. Also included in this family is TM1010 from Thermotoga maritima, a protein of unknown function. Some but not all members of this family have N- or C-terminal carboxymuconolactone decarboxylase domains in addition to the cupin domain. Members of this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.93774e-61
NC_018870.1\|WP_015051233.1\|2192652_2193525_+\|NAD(+)/NADH-kinase	gnl\|CDD\|223139	COG0061, nadF, NAD kinase [Coenzyme metabolism].	2.99623e-64
NC_018870.1\|WP_015051239.1\|2200687_2201218_-\|flavodoxin	gnl\|CDD\|180760	PRK06934, PRK06934, flavodoxin; Provisional.	2.9286e-50
NC_018870.1\|WP_015051241.1\|2202147_2203353_-\|iron-containing-alcohol-dehydrogenase	gnl\|CDD\|341466	cd08187, BDH, Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process. The butanol dehydrogenase (BDH) is involved in the final step of the butanol formation pathway in anaerobic micro-organism. Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process. Activity in the reverse direction is 50-fold lower than that in the forward direction. The NADH-BDH has higher activity with longer chained aldehydes and is inhibited by metabolites containing an adenine moiety. This protein family belongs to the so-called iron-containing alcohol dehydrogenase superfamily. Since members of this superfamily use different divalent ions, preferentially iron or zinc, it has been suggested to be renamed to family III metal-dependent polyol dehydrogenases. This family also includes E. coli YqhD enzyme, an NADP-dependent dehydrogenase whose activity measurements with several alcohols demonstrate preference for alcohols longer than C3. The active site of YqhD contains a Zn metal, and a modified NADPH cofactor bearing OH groups on the saturated C5 and C6 atoms, possibly due to oxygen stress on the enzyme, which would functionally work under anaerobic conditions.	0
NC_018870.1\|WP_015051235.1\|2194080_2195835_+\|NADH-quinone-oxidoreductase-subunit-NuoF	gnl\|CDD\|224806	COG1894, NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion].	0
NC_018870.1\|WP_148276009.1\|2193574_2194084_+\|NADH-quinone-oxidoreductase-subunit-NuoE	gnl\|CDD\|376507	pfam01257, 2Fe-2S_thioredx, Thioredoxin-like [2Fe-2S] ferredoxin.	1.37734e-69
NC_018870.1\|WP_015051249.1\|2215117_2215693_+\|manganese-catalase-family-protein	gnl\|CDD\|153117	cd07908, Mn_catalase_like, Manganese catalase-like protein, ferritin-like diiron-binding domain. This uncharacterized bacterial protein family has a ferritin-like domain similar to that of the manganese catalase protein of Lactobacillus plantarum and the bll3758 protein of Bradyrhizobium japonicum. Ferritin-like, diiron-carboxylate proteins participate in a range of functions including iron regulation, mono-oxygenation, and reactive radical production. These proteins are characterized by the fact that they catalyze dioxygen-dependent oxidation-hydroxylation reactions within diiron centers; one exception is manganese catalase, which catalyzes peroxide-dependent oxidation-reduction within a dimanganese center. Diiron-carboxylate proteins are further characterized by the presence of duplicate metal ligands, glutamates and histidines (ExxH) and two additional glutamates within a four-helix bundle. Outside of these conserved residues there is little obvious homology. Members include bacterioferritin, ferritin, rubrerythrin, aromatic and alkene monooxygenase hydroxylases (AAMH), ribonucleotide reductase R2 (RNRR2), acyl-ACP-desaturases (Acyl_ACP_Desat), manganese (Mn) catalases, demethoxyubiquinone hydroxylases (DMQH), DNA protecting proteins (DPS), and ubiquinol oxidases (AOX), and the aerobic cyclase system, Fe-containing subunit (ACSF).	6.6254e-70
NC_018870.1\|WP_015051240.1\|2201259_2202123_-\|aldo/keto-reductase	gnl\|CDD\|381359	cd19133, AKR_AKR5F1, the AKR5F family of aldo-keto reductase (AKR). Klebsiella sp. 2,5-diketo-D-gluconic acid reductase (2,5-DKG reductase) is a founding member of aldo-keto reductase family 5 member F1 (AKR5F1). It catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	0
NC_018870.1\|WP_015051253.1\|2219325_2219844_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	9.24775e-14
NC_018870.1\|WP_015051245.1\|2212251_2212671_+\|hypothetical-protein	gnl\|CDD\|372378	pfam12910, PHD_like, Antitoxin of toxin-antitoxin, RelE / RelB, TA system. This domain appears to be the N-terminus of the RelB antitoxin of toxin-antitoxin stability system or prevent-host death system. Together RelE toxin and the RelB antitoxin form a non-toxic complex. Although toxin-antitoxin gene cassettes were first found in plasmids, it is clear that these loci are abundant in free-living prokaryotes, including many pathogenic bacteria, and these toxin-antitoxin loci provide a control mechanism that helps free-living prokaryotes cope with nutritional stress.	1.78407e-56
NC_018870.1\|WP_015051248.1\|2214587_2214824_-\|VanW-family-protein	gnl\|CDD\|377286	pfam04294, VanW, VanW like protein. Family members include vancomycin resistance protein W (VanW). Genes encoding members of this family have been found in vancomycin resistance gene clusters vanB and vanG. The function of VanW is unknown.	4.31687e-12
NC_018870.1\|WP_015051186.1\|2213389_2213770_-\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|284650	pfam07282, OrfB_Zn_ribbon, Putative transposase DNA-binding domain. This putative domain is found at the C-terminus of a large number of transposase proteins. This domain contains four conserved cysteines suggestive of a zinc binding domain. Given the need for transposases to bind DNA as well as the large number of DNA-binding zinc fingers we hypothesize this domain is DNA-binding.	3.39494e-24
NC_018870.1\|WP_015051250.1\|2216224_2217454_-\|multidrug-effflux-MFS-transporter	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.46589e-77
NC_018870.1\|WP_015051236.1\|2195852_2199329_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|139246	PRK12814, PRK12814, putative NADPH-dependent glutamate synthase small subunit; Provisional.	0

>NC_018870.1|WP_015051241.1|2202147_2203353_-|iron-containing-alcohol-dehydrogenase
MIKFQFYNPTRLIFGAGSLAQLGNAVRPYGKKALLVIGGGSVKKSGAFDRAVASLKAAGVSVVEFSGVEPNPRLSTVVRAAEVAKNEACDVVIGMGGGSVMDASKVIAASVLYEGHPRDMLVRAGKVPRLPERALPIITVPTLAATGSEMNNGAVITIDDEGEKLKTFVQAEVLYPRVAVVDPELTVTVPKNHTAFGVCDIITHVTEGYFNGIDGTPLQDRFAEGVMLTVLEWGPKAVNNGSDLEARTQIQWASIVALNGWVQAGVNAPYPVHQIEHTLSALYDIPHGAGLAVVNPAWMRFAARFRPDRFAKFAQRIFGLAATGKDDLSLAMEGIDRFEGFLRSIGCPTRLSELGIGEITEEMLFGYAEETLKVLRDEEGRLPGRPPLRKEDIVEILRMAM
>NC_018870.1|WP_015051240.1|2201259_2202123_-|aldo/keto-reductase
MEKVVLNNGVEMPVLGFGVYRITDLKQCEQCVYDAIMVGYRLIDTAAAYMNEEAVGKAIKRAIEEGMVKREELFITTKLWIQDAGYESTKKAFEKSLKRLQLDYIDLYLIHQPFGDVHCSWRAMEELYREGLIRAIGVSNFQPDRLMDLIVHHEVIPTVNQIEIHPFYQQTESIEFMKKYNAQPESWGPFAEGRNNIFQNEVLVSIAKEYDKTVAQVILRWLIQRGIVTIPKTVHKERMIENIGIFDFELSQEDVEKIAALDTKKSLFLSHNDPETVKWLGTLKFDV
>NC_018870.1|WP_015051239.1|2200687_2201218_-|flavodoxin
MAYSKFLIAYFSRRGNNYVNGRIMNLPIGNTEVAAKKIQELIGGEVFEIKTVKAYPEDYTETTEVAKEEKRQNARPELTDKLDDIDSYDVIFLGYPNWWGTMPMAVFTFLESYDFAGKTIVPFCTHEGSGMGSSERDIKKLCPNAKVLPGLAIRGSNVNRADKDVADWLERLGLIS
>NC_018870.1|WP_015051238.1|2200230_2200668_-|cupin-domain-containing-protein
MGKTELRNLGSSIIFPLGQKIENEYFRGTVWVETLVSNDSVFNCPIYNVTFEPGARNNWHKHPGGQILLVTGGRGYYQEEGRPVQIIKEGDVVKIQPDVKHWHGAAQDSWLSHIAITANPQKGEVEWMEPVSDEYYLRLKIEEEA
>NC_018870.1|WP_015051237.1|2199699_2200098_-|MerR-family-transcriptional-regulator
MTIAEVSKRFGLSPDTLRYYERIGLIPRVSRNESGIRNYTEEDCKWIEFIKCMRSAGVQVETLVEYVTLLQQGDKTIEARKQILIEQREKLFSRIEEMERALERLNFKIKEYETKLIPAENKLKRLATTSTL
>NC_018870.1|WP_015051236.1|2195852_2199329_+|FAD-dependent-oxidoreductase
MLKIIIDGKELAAKRGQTILEVASENGIHIPTLCYDERLKPYGGCGICVVEVQGSSKLFRSCATEVTEGMVVFTNTPRVRKSRKLTLEMLLSDHTGDCLGPCTRACPAHVDVQGYIGLIANRRYREAVALIKERLPIPASIGRICPHPCEDACRRQLVEAPISIAHLKRFVADLDLKSGEPYRPEIRPATGKSVGIVGAGPAGLTAAYHLARDGHGVTVYDAMPQGGGMLRYGIPAYRLPKTVLDEEIRLIAEMGVRFCYNTRLGSDISIDLLRKRHDAIFLAIGAWKSSSIRCPGENIPGVLGGIDFLREVALHGKAEIGNVVAVIGGGNTAIDAARTAVRLGAERVLILYRRTKAEMPAEDKEIAEAEEEGVEFRFLVSPMEICARNGRVCAIRLQKMQLGEPDATGRRRPVPIPGAEETLPVDTVIRAIGQSVRPDGLACFSLTKWGTIAVDENTMATEIPGVFAGGDVVTGPSIAIEAVAQGIKAAHAISAYLNGRILSPKNQYVVERQGLSEAEFIDHPRINRAEMPHLTPEERRYNFREVNLGLQEPDAQVEASRCLECGCRDYFECKLIRYAREYNVQPERLSGSKHREITSQDDHPFLELNSGKCILCGLCVRICDEVMGVTALGLVHRGFDTVVAPEFGLPLRESACVSCGQCAAVCPTGALMERQAIPKNVPLATQENPSVCPFCGAGCEQVVNTRGDLVLRCLPAPGGILCVKGRFGFQIFDQERLTVPLVRHNGKLVEVSWQEAMDEIAKTVKRIGTGRRDSPFALFISPFCTMEEAQAAICFGRQALVTEKIGSFTPDAARGLMDIFGIIPDPPGYQELESADLILLVGSLNESQSVAVKIRKAIQRGARLALLSPEPGLAGDLATMWVKPGNSGNSTAFLKQVLAAVVNNTPATGRVLKGFTELRDALAGITPGRDAEDLAHLYSSAKQPLIVVDGSTVTTAAVQLLADLSLVTGQTGRFRSGLLIITPGSNQVGLRKLGIVTGDSLLEEKPHGVFIFGEDPVGGGSPASGQLKNMEFLVVLSPFLTPTARLADVVLPGATPLETGGTFIGSDGRERSFSGVRDPLSGRTNLQIISDLAAALGVERLPGRGESVRFSVNSVTPHQREGEIRLVLPEDTELFRLQPELDPALRIFKARLVRSGLK
>NC_018870.1|WP_015051235.1|2194080_2195835_+|NADH-quinone-oxidoreductase-subunit-NuoF
MKIRVGMGSCGIAAGSLKVRERIVEEIERRGLDLQVQPTGCIGMCHNEPLLDVITGDGRIFTYGHVTPELVGEIFEKHIIGGVPLTQHLVSTSENTNDFLKEQVRVALRNCGEINPECIDDYLDRGGYQALKQALSSTPEEVIQEIRVSGLRGRGGAGFPTWFKWQAVRQNPGSVKYVVCNADEGDPGAFMDRSILEGDPHSVLEGMAIAGYATGAKHGFIYCRAEYPLAVRRLELAIAQARERGLLGRNIFGSGFTFEVAVKEGAGAFVCGEETALIASLEGERGMPRLKPPYPAQYGYWGKPTNINNVETYANVPWIISHGGKAFASMGTEKSKGTKVFALAGKIRRGGLVEVPMGLSLRDVIFNIGGGIKDNRRFKAVQLGGPSGGCIPESLLDIPVDYESINQTGAIMGSGGMVVMDDTTCMVDVARFFLDFTQKESCGKCVQCRIGTRRMLEILERICTGEGRPGDEELLEEIAIQVKEGSLCGLGQSAPNPVLTTLRYFREEYTAHINDKNCPAKQCKALITYRIDPARCQGCGACARKCPAKCISGEKKKPHVIDRELCLKCGNCLDVCHYNAVIIE
>NC_018870.1|WP_148276009.1|2193574_2194084_+|NADH-quinone-oxidoreductase-subunit-NuoE
MEELLRNDFNTWSRLQEVVKTYRGQPGSLVTVLQRVQAIYGYLPQPVMRYLSGELQIKPARIYGVATFYSQFRLTPVGKYLILLCQGTACHVNGSERIRSAVCEELRIRPGETTHDRLFTLSDVACLGCCSLAPVMMINGQAYGPLTTDKALKIIRELAAGEKKEEAAP
>NC_018870.1|WP_015051233.1|2192652_2193525_+|NAD(+)/NADH-kinase
MKIIIVYKDDAGAQRLARELHKKLESRGASAACMGLREMTKSALWQADLVLVLGGDGTFLKTARCCATQGIPVLGVNLGTIGFLSSIEPEQLLQEVDRILNRDYRIESRMMLDVRLIRDGMEVYHGLSMNDVVIRACVSHTITIGLQIDRLFHTTYTGDGVVCATPTGSTAYSFSAGGPVLDVDLPALVITPICPQLSCSRALVVRSSARLVFELVAGHPTAFSVDGEDELPLAKGDRVEVVRSPVTAKIAEVFPVSSLDRVLRRFERLNNTRAEASNDMNILLQSCYVL
>NC_018870.1|WP_015051232.1|2192325_2192508_+|hypothetical-protein
MEQHPEVISYFIEQGINPIFCVGAFPGCLGKLLEIKGVPNPDAFIRGLNDYLLERTKKSE
>NC_018870.1|WP_015051245.1|2212251_2212671_+|hypothetical-protein
MLEELKFTEARGGFSALYNRVFNHYRPVIIRRRQAEEVLVLRADLQKLLLEKYRLKPEVIREEDGSVTLALDELELYANGRTVEEATQELVQDLKFYAQDYLERSQLFINAPNRRAHFPYILRVLLCDSDEEIRSLLEI
>NC_018870.1|WP_015051246.1|2212673_2212898_+|hypothetical-protein
MPPKFGDLKRYCEKNGWVLVRSSDHWYYENVLAEGTVLRTKVSRAVHKEIPKQLWQRILKKQLKITEKEFWESL
>NC_018870.1|WP_015051186.1|2213389_2213770_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MRYINHCISKRIVEIAKAESKAIALENLLGIRERTKGSKKFNRMMSGWNFRELASFIEYKAALQGVPVIYVDPKETSKTCPKCGNVSRYNRKKQGWFKCTKCGYQSDADRVGAINIAARALDALGA
>NC_018870.1|WP_015051248.1|2214587_2214824_-|VanW-family-protein
MDTDVASCPAKNPFGSGATVFFNYIDLQVRNDTNQTFYLRLWLTDTHLCGEWRSDRPILYTYQVYKFPARMPLISIKG
>NC_018870.1|WP_015051249.1|2215117_2215693_+|manganese-catalase-family-protein
MSMEPPETKGCVTPAVFKCAYPAPYPEVRVAGPNPKYAQLLLEDYAGMVSELTAVTQYIYHHFVLEDENREVADLLSCIALVEMHHQEILAQTIKMLGVNPRYRTIERNNTERYWNATFVFYGTSLCDRLTADVASEWAAIANYRKHQRMIDDPYVKKILDRIILDELHHVVLFNQVIEKYCQPHFPKYKT
>NC_018870.1|WP_028990850.1|2215756_2216146_-|hypothetical-protein
MRNEPGLTERILPALLVGTAGFVSGIFLLDIQGIKALGLGDRAAAALIMGWAFLMLLSGTPAGWQAGKYSVKLPFILAWAGAFAPMVAWFAGMEAAWPESLIYAWLLAFAGSWVGLGLGLVLCRKKAEH
>NC_018870.1|WP_015051250.1|2216224_2217454_-|multidrug-effflux-MFS-transporter
MLRTESIPDVNINRKQKYLGEKGLLALLGLLSAFVPLSTDLYLPSLPGIAEYFRASVHLTNLTLILFFLFFSAGTLLWGPLSDKYGRKPILLIGLAVYTAASSLCACAESIYLLIVFRVFQAVGGSAAGSVATAMVKDLYSGRRREAVLALVQSMVLLAPAVAPVLGAFLLKFTTWRGVFWALAGIGLLSLAGALAMEETIEHHYEGTIIQTMGRLGTVLKNPGFTSLLAVFSILGISSMAFIASSSYIYIDGFGLSEQTYSYYFALNAMGLIAGPMLYLQLSKRFSRRSIISSCFLVVALSGVLITMLGNFRPWLFALTLLPSSLAGSCVRPPGTNLMLEQQAGDAGSASSLISCFGILMGSVGMSIISLDWGNTIVALGVLTAITGLLCEALWVWTANKPFIRQVHD
>NC_018870.1|WP_015051251.1|2218185_2218614_-|hypothetical-protein
MRKKESTLKALYTYIIFGGIYLLGAVIWFVISYFRNELDSPVTLFWLAGAIIYIIMMLVSAKKVVKLKSGAVSAASLQPDERAEYITGKTAHVTILWGCLLLLAYIGGETGSSGKVPIEACIFLLAVVVIYFGHYIYYLRKY
>NC_018870.1|WP_015051252.1|2218637_2218844_-|helix-turn-helix-transcriptional-regulator
MINNIRAMREQRGWTQEHLASLVQVSRQTINSLEAGRYKPSIVLALKLAHVFKVPLEEVFQLESTDWE
>NC_018870.1|WP_015051253.1|2219325_2219844_-|alpha/beta-fold-hydrolase
MIGMQNVAFDKANNTSVEPTIIKDGLAIYCIGQDDPILLMPYPHGFTTTSMAEGALTSLLVSLDRKVITFDPLGAYRSTRPAQVDLPEMLACAEETLNACQVSGSVDVIGHSMGSLCALAFAIEHPKLVQRLILIGSMSGFPAIRRWGMPNNWCWWKDPEYWRFAWTCEKSI

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Crispr_ID: NC_018870_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018870_5

2439388-2440146

Orphan

Consensus_repeat	Method
CCGCGTTTCAATTCCTCATAGGTACGCTGAGAAC	PILER-CR
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CRISPRCasFinder
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CRT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	PILER-CR

11 spacers

cas6,cas2,cas1

The CRISPR arrays of NC_018870_5

>merge|NC_018870|5|2439388-2440146|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
CGGGTTTCAATTCCTCATAGGTACGCTGAGAACGCATTGGCTTTCATCTCCCCCTCGGCATGCCCGGCGTTTCAATTCCTCATAGGTACGCTGAGAACCAGGTTTGGCGGTTATTTGTTCCTGAACGACTCCACGTTTCAATTCCTCATAGGTACGCTGAGAACAGGTAGAGGGGTTGAAGGGAGTTCTCCCCCTGGCCGCGTTTCAATTCCTCATAGGTACGCTGAGAACGTCAGATAAAAATTCAGCCCGCTAAGGAGGTGTCGGTTTCAATTCCTCATAGGTACGCTGAGAACTTTCCGTTAGCGTCATATACTATCGCCCCCTTTGTAAGTTTCAATTCCTCATAGGTACGCTGAGAACGCCGCGGTTGGCGCAGTATACGGGGAAGAAGTTGAGTTTCAATTCCTCATAGGTACGCTGAGAACCCCCTTTACCTCTCCTTCATCATCCTTTATTGCCTGTTTCAATTCCTCATAGGTACGCTGAGAACTTGATGCTGTTACTGCGGCAATAACCGTAGGTGCGGGTTTCAATTCCTCATAGGTACGCTGAGAACCTGCTTTCTCCCTCTTTTTTTCTAACTCTAATGCCGGTTTCAATTCCTCATAGGTACGCTGAGAACTACCATGGGACAAATTCCCTGGGATAATCTGCCTTGGGTTTCAATTCCTCATAGGTACGCTGATAACGCTCTGGATGCTTGGAAGAAATGCAAGGAACGGAATAGTTTCAATTCCTCATAGACAATCATGTCAC

>NC_018870|5|4|2439388-2439618|PILER-CR
CGGGTTTCAATTCCTCATAGGTACGCTGAGAACG	CATTGGCTTTCATCTCCCCCTCGGCATGCCC
GGCGTTTCAATTCCTCATAGGTACGCTGAGAACC	AGGTTTGGCGGTTATTTGTTCCTGAACGACTC
CACGTTTCAATTCCTCATAGGTACGCTGAGAACA	GGTAGAGGGGTTGAAGGGAGTTCTCCCCCTGGC
CGCGTTTCAATTCCTCATAGGTACGCTGAGAACGTCAGATAAAAATTCAGCCCGCTAAGGAGGTGTCGGTTTCAATTCCTCATAGGTACGCTGAGAACTTTCCGTTAGCGTCATATACTATCGCCCCCTTTGTAAGTTTCAATTCCTCATAGGTACGCTGAGAAC	GCCGCGGTTGGCGCAGTATACGGGGAAGAAGTTGA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CCCCTTTACCTCTCCTTCATCATCCTTTATTGCCT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TTGATGCTGTTACTGCGGCAATAACCGTAGGTGCGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CTGCTTTCTCCCTCTTTTTTTCTAACTCTAATGCCG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TACCATGGGACAAATTCCCTGGGATAATCTGCCTTGG


>NC_018870|5|5|2439391-2440146|CRISPRCasFinder
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCATTGGCTTTCATCTCCCCCTCGGCATGCCCGGC
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CAGGTTTGGCGGTTATTTGTTCCTGAACGACTCCAC
GTTTCAATTCCTCATAGGTACGCTGAGAAC	AGGTAGAGGGGTTGAAGGGAGTTCTCCCCCTGGCCGC
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GTCAGATAAAAATTCAGCCCGCTAAGGAGGTGTCG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TTTCCGTTAGCGTCATATACTATCGCCCCCTTTGTAA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCCGCGGTTGGCGCAGTATACGGGGAAGAAGTTGA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CCCCTTTACCTCTCCTTCATCATCCTTTATTGCCT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TTGATGCTGTTACTGCGGCAATAACCGTAGGTGCGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CTGCTTTCTCCCTCTTTTTTTCTAACTCTAATGCCG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TACCATGGGACAAATTCCCTGGGATAATCTGCCTTGG
GTTTCAATTCCTCATAGGTACGCTGATAAC	GCTCTGGATGCTTGGAAGAAATGCAAGGAACGGAATA
GTTTCAATTCCTCATAGACAATCATGTCAC

>NC_018870|5|4|2439391-2440146|CRT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCATTGGCTTTCATCTCCCCCTCGGCATGCCCGGC
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CAGGTTTGGCGGTTATTTGTTCCTGAACGACTCCAC
GTTTCAATTCCTCATAGGTACGCTGAGAAC	AGGTAGAGGGGTTGAAGGGAGTTCTCCCCCTGGCCGC
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GTCAGATAAAAATTCAGCCCGCTAAGGAGGTGTCG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TTTCCGTTAGCGTCATATACTATCGCCCCCTTTGTAA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCCGCGGTTGGCGCAGTATACGGGGAAGAAGTTGA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CCCCTTTACCTCTCCTTCATCATCCTTTATTGCCT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TTGATGCTGTTACTGCGGCAATAACCGTAGGTGCGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CTGCTTTCTCCCTCTTTTTTTCTAACTCTAATGCCG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TACCATGGGACAAATTCCCTGGGATAATCTGCCTTGG
GTTTCAATTCCTCATAGGTACGCTGATAAC	GCTCTGGATGCTTGGAAGAAATGCAAGGAACGGAATA
GTTTCAATTCCTCATAGACAATCATGTCAC

>NC_018870|5|5|2439721-2440079|PILER-CR
	CATTGGCTTTCATCTCCCCCTCGGCATGCCC
GGCGTTTCAATTCCTCATAGGTACGCTGAGAACC	AGGTTTGGCGGTTATTTGTTCCTGAACGACTC
CACGTTTCAATTCCTCATAGGTACGCTGAGAACA	GGTAGAGGGGTTGAAGGGAGTTCTCCCCCTGGC
CGCGTTTCAATTCCTCATAGGTACGCTGAGAACGTCAGATAAAAATTCAGCCCGCTAAGGAGGTGTCGGTTTCAATTCCTCATAGGTACGCTGAGAACTTTCCGTTAGCGTCATATACTATCGCCCCCTTTGTAAGTTTCAATTCCTCATAGGTACGCTGAGAAC	GCCGCGGTTGGCGCAGTATACGGGGAAGAAGTTGA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CCCCTTTACCTCTCCTTCATCATCCTTTATTGCCT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TTGATGCTGTTACTGCGGCAATAACCGTAGGTGCGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CTGCTTTCTCCCTCTTTTTTTCTAACTCTAATGCCG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TACCATGGGACAAATTCCCTGGGATAATCTGCCTTGG
GTTTCAATTCCTCATAGGTACGCTGATAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018870.1\|WP_081578676.1\|2458292_2459963_+\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_018870.1\|WP_015051469.1\|2438070_2438394_+\|transposase	unknown	unknown	gnl\|CDD\|366690
NC_018870.1\|WP_015049782.1\|2453138_2453459_-\|IS66-family-insertion-sequence-hypothetical-protein	unknown	unknown	gnl\|CDD\|225511
NC_018870.1\|WP_015051462.1\|2434149_2434449_-\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015051476.1\|2464856_2465594_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NC_018870.1\|WP_015051465.1\|2436159_2436408_-\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015051463.1\|2434441_2434999_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|366760
NC_018870.1\|WP_015051464.1\|2435818_2436160_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NC_018870.1\|WP_015051471.1\|2440644_2441883_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376773
NC_018870.1\|WP_148275911.1\|2436557_2436800_+\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015051472.1\|2448405_2449620_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018870.1\|WP_081578676.1\|2446079_2447750_-\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_018870.1\|WP_015051478.1\|2465873_2466866_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_018870.1\|WP_015051477.1\|2465607_2465871_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_018870.1\|WP_015051468.1\|2437832_2438030_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275209
NC_018870.1\|WP_015051475.1\|2452788_2453145_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NC_018870.1\|WP_037999814.1\|2436950_2437226_+\|BrnT-family-toxin	unknown	unknown	gnl\|CDD\|225481
NC_018870.1\|WP_148276018.1\|2437231_2437552_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372110
NC_018870.1\|WP_015051472.1\|2442275_2443490_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018870.1\|WP_015051470.1\|2438417_2439062_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|379098

Protein	Function_ID	Function_description	E-value
NC_018870.1\|WP_081578676.1\|2458292_2459963_+\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.8014e-28
NC_018870.1\|WP_015051469.1\|2438070_2438394_+\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	1.36302e-09
NC_018870.1\|WP_015049782.1\|2453138_2453459_-\|IS66-family-insertion-sequence-hypothetical-protein	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.000769281
NC_018870.1\|WP_015051476.1\|2464856_2465594_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.60943e-42
NC_018870.1\|WP_015051463.1\|2434441_2434999_-\|ATP-binding-protein	gnl\|CDD\|366760	pfam01695, IstB_IS21, IstB-like ATP binding protein. This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.	1.08045e-15
NC_018870.1\|WP_015051464.1\|2435818_2436160_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	2.59884e-33
NC_018870.1\|WP_015051471.1\|2440644_2441883_-\|IS110-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	5.273e-26
NC_018870.1\|WP_015051472.1\|2448405_2449620_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.31767e-41
NC_018870.1\|WP_081578676.1\|2446079_2447750_-\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.8014e-28
NC_018870.1\|WP_015051478.1\|2465873_2466866_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	8.78104e-171
NC_018870.1\|WP_015051477.1\|2465607_2465871_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.43479e-28
NC_018870.1\|WP_015051468.1\|2437832_2438030_+\|hypothetical-protein	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	4.96046e-15
NC_018870.1\|WP_015051475.1\|2452788_2453145_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	1.30076e-55
NC_018870.1\|WP_037999814.1\|2436950_2437226_+\|BrnT-family-toxin	gnl\|CDD\|225481	COG2929, COG2929, Uncharacterized protein conserved in bacteria [Function unknown].	3.61785e-09
NC_018870.1\|WP_148276018.1\|2437231_2437552_+\|hypothetical-protein	gnl\|CDD\|372110	pfam12441, CopG_antitoxin, CopG antitoxin of type II toxin-antitoxin system. CopG antitoxin is a member of a type II toxin-antitoxin system family found in bacteria and archaea. Most antitoxins encoded by the relBE and parDE loci belong to the MetJ/Arc/CopG family of dimeric proteins which bind DNA through N-terminal ribbon-helix-helix (RHH) motifs. The toxin for CopG proteins falls into the family BrnT_toxin, pfam04365.	8.50953e-11
NC_018870.1\|WP_015051472.1\|2442275_2443490_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.31767e-41
NC_018870.1\|WP_015051470.1\|2438417_2439062_+\|IS3-family-transposase	gnl\|CDD\|379098	pfam13276, HTH_21, HTH-like domain. This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.	7.64926e-08

>NC_018870.1|WP_015051470.1|2438417_2439062_+|IS3-family-transposase
MGYKVSLVLRIIGISRSTYYPNLKRQPKPRIFAGGRPKSHYTFTSDNKVVSNEQVKEWLCELITAEGFAYGYLKLTHCLRRKFHLIINKKKVYRLCKELDILRPQRKIKRKHPRRLARNRVITASNQLWEADLKYGYIAGEDRFFFIMPIIDVFDRCIVAYHIGLSCEAKDARVMSLPAMPKRMQRLSTSSTFTTKPGFIQQLNTYHRWNAINC
>NC_018870.1|WP_015051469.1|2438070_2438394_+|transposase
MNRKQYSPEMKMQIVKETLETGNASIVARRHDIAPSLVARWARCYKRYGTFYPQKEVPGTNGSCIPPDYKKITKENEQLKKLLGEKDLEIAILRDLLKKTNLPFPIK
>NC_018870.1|WP_015051468.1|2437832_2438030_+|hypothetical-protein
MEKVLERSNMLRALRRVKSNKGADGVDGMEIKSLRPYLKEHWPKIKEELLKGTYKLFSPLTRLNS
>NC_018870.1|WP_148276018.1|2437231_2437552_+|hypothetical-protein
MAKKKELPEFKGDEIPEFASEEEAAEFFDRHSFAEAMERGVLAPDDPAEPDPELAATSKTKRVTLRLRVSQIEAAKEIAKRKDIPYQTLLRSWIAEGIRREMEGKG
>NC_018870.1|WP_037999814.1|2436950_2437226_+|BrnT-family-toxin
MAKAKRFEWDSRNVNHIARHNVKPEEVEEVFLSRPLIRKARSGLKVAMGRTDAGHYLFVVFALKSSDVIRVITARDMSTSERRYYRRERGE
>NC_018870.1|WP_148275911.1|2436557_2436800_+|hypothetical-protein
MSDVVEKPTGGSFPSDLKLGTTTWCPYCGGVKGFVWDTDAFTSRYPNCGVSTEDSYVCVCSSGPVKGGRASTRVSASTPP
>NC_018870.1|WP_015051465.1|2436159_2436408_-|hypothetical-protein
MPSTVRVSNRAWKALKEIAEQTGETMQGVLERAVEAYRRQWLLERANKAYAALRSDPEKWDEEVAERREWEAPLADGLEGSE
>NC_018870.1|WP_015051464.1|2435818_2436160_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MASPLRGEVWLVDLDPVRGHEQAGKRPALVISVDAFNTGPAGLVIVLPMTSKDKGIPLHVKVDPPEGGVKATSFVKCEDIRSVSTEKLVAKLGRVSAEAMILVEDRVRILVGL
>NC_018870.1|WP_015051463.1|2434441_2434999_-|ATP-binding-protein
MEQQALTVLPKYQMAYADVEILDVDPFSTVRFDRNRYSKRHYGWQPQYRQNASIYRFRCCCLQGWPPGLLITAPALAPELAEAQDKYQLRRIEQGINKAALLIVDDLSYITFNRRHSELLFKLIAERTESASIISTNLEFSRWTELFEDPMLTIYSCHNLLSVGNNPGLIIIYLKENFLGRRLNV
>NC_018870.1|WP_015051462.1|2434149_2434449_-|hypothetical-protein
MSDVMDAFEAFSSVLTDNFHKKKVNVEFFCGECCKKAVKGKLEHIDRHVIILDGDEKDIKVITFGDKGPIDIEFVEKIIIPIKNICSVEIPSRDDKRED
>NC_018870.1|WP_015051471.1|2440644_2441883_-|IS110-family-transposase
MKLFVGIDVSMKDFKARMFDAEGEEIAKRMRYKNDDPGAESFVKYLVEICGANEVDSLRIGMESTSVYGWHLQMRLAGEPLLASFHPQVYVFNPKVIANFRKQYVDIPKDDWFDCLVIADRLRFGRLPESCQVDFRYLPLQRLTRFRYHLIQTITREKNYFLTNLFLKFNTICQDKVLSDIFGATSEAILTEFLSPEEIAARPLDELIDFLMEKGKSHFSNPEATAKALKHAAACAYRLHGSLLEPVNLILATSLQTICTLEQQVKSIDRAIEKELSHFPNTLQSMPGMGPVCTAGIIAEIGDIHRFDNEKAVAKFAGLTWRKHQSGEFEADDTPLTKTGNVYLRYYFVMAADSVRKWDPRFAEFYARKFKESSTHHHRRALVLTARKLVRVVDALLRSNQLYVPQGQRKVV
>NC_018870.1|WP_015051472.1|2442275_2443490_+|IS110-family-transposase
MDVVFPYCCGLDVHKNSVVACVITPDEKEIRTFGTMTRDLLNLADWLTSKGCTHVAMESTGVYWKPIYNILEQYQLELLVVNAKHIKAVPGRKTDVKDAEWIADLLRHGLLKGSYIPDREQRELRELVGYRKSLVEERAREVNRIQKTLEGAGIKLSSVATDVVGVSGRAMIEGIISGIDDPAVLADFAQKKLKKKKEQLEQALFGLVGKHQRLLLAAQLRHIDYLDQEIARLDQQIEERMRPFEAELALLDTIPGVGRRTSQVILACIGADMSRFPSAAHLSSWAGVAPGNNESAGKRKSGKTTKGNTLLHTTLIQAARAASRTKNTYLSALYHRVAARRGANRAAVAVAHSILVSVYYMLIRRVPYHDLGGDYFEKRNSKAVVNRAVKQLEQLGYRVSIEVA
>NC_018870.1|WP_081578676.1|2446079_2447750_-|IS1634-family-transposase
MWYNVDMYIRTIQRKNKDGSVVRYIQLAHNQWDPQARCAKAKVLFNFGREEEVDREALKRLVKSINRFLGPGETLRYEAETGAAPLKFITSRPLGGAWVLDRLWEELGIKGVLETLLKKRQYKTPVERAIFAMAANRALDPMSKRGVEEWVKEDAVIPGVEEIPLQQLYRAMDFLLENEAELQKQVYYSVANLLNLEVDILYFDTTSTYFEIEDEDEDGGLRRRGHSKDHRPDLPQAVIGLAVTRDGIPVRCWVWPGNTADISVVEQVKKDLIGWKLGRVITVLDRGFNSEDNLRCLQRAGGHYIAGEKLRSGKENTVQALKRGGRYQTVRDNLEVKEIVVGNGEARERYILVRNPEEAARDKARREKIIKELEEQLPHIKTHAKAVCELMAHPVYGRYLKLDSRSLPKIDRAKIREEEKLDGKYLLRTSDDTLSAEDVALGYKQLLLVEDAFRTLKSRLELRPVYHRLEDRIRSHVLLCWLALLLIRIAENRTGQTWCSLRATLQRMQLGEFSGTAGQVRQRTETTPAQKQIFKALAVKEPPLLFSINPTAKKNA
>NC_018870.1|WP_015051472.1|2448405_2449620_+|IS110-family-transposase
MDVVFPYCCGLDVHKNSVVACVITPDEKEIRTFGTMTRDLLNLADWLTSKGCTHVAMESTGVYWKPIYNILEQYQLELLVVNAKHIKAVPGRKTDVKDAEWIADLLRHGLLKGSYIPDREQRELRELVGYRKSLVEERAREVNRIQKTLEGAGIKLSSVATDVVGVSGRAMIEGIISGIDDPAVLADFAQKKLKKKKEQLEQALFGLVGKHQRLLLAAQLRHIDYLDQEIARLDQQIEERMRPFEAELALLDTIPGVGRRTSQVILACIGADMSRFPSAAHLSSWAGVAPGNNESAGKRKSGKTTKGNTLLHTTLIQAARAASRTKNTYLSALYHRVAARRGANRAAVAVAHSILVSVYYMLIRRVPYHDLGGDYFEKRNSKAVVNRAVKQLEQLGYRVSIEVA
>NC_018870.1|WP_015051475.1|2452788_2453145_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MLNEAGIDRVYLACGATDLRKSIDGLAVLVKEGFELDPFSSCLFVFCNRKRDKLKILHWEHNGFWLYYRRLEKGKFIWPQDTTSSTITISRRELRWLLDGLPLKQPKAHPEVKARTIL
>NC_018870.1|WP_015049782.1|2453138_2453459_-|IS66-family-insertion-sequence-hypothetical-protein
MTRAELQKLWEARIAEYRESGQSVKEWCASHEGINPRQLWYWLRKFKNQTPAPPEISNRWLSVEISEEDSLEQALLVKIGPASIEVRPGFDPALLTKVVQVLMALC
>NC_018870.1|WP_081578676.1|2458292_2459963_+|IS1634-family-transposase
MWYNVDMYIRTIQRKNKDGSVVRYIQLAHNQWDPQARCAKAKVLFNFGREEEVDREALKRLVKSINRFLGPGETLRYEAETGAAPLKFITSRPLGGAWVLDRLWEELGIKGVLETLLKKRQYKTPVERAIFAMAANRALDPMSKRGVEEWVKEDAVIPGVEEIPLQQLYRAMDFLLENEAELQKQVYYSVANLLNLEVDILYFDTTSTYFEIEDEDEDGGLRRRGHSKDHRPDLPQAVIGLAVTRDGIPVRCWVWPGNTADISVVEQVKKDLIGWKLGRVITVLDRGFNSEDNLRCLQRAGGHYIAGEKLRSGKENTVQALKRGGRYQTVRDNLEVKEIVVGNGEARERYILVRNPEEAARDKARREKIIKELEEQLPHIKTHAKAVCELMAHPVYGRYLKLDSRSLPKIDRAKIREEEKLDGKYLLRTSDDTLSAEDVALGYKQLLLVEDAFRTLKSRLELRPVYHRLEDRIRSHVLLCWLALLLIRIAENRTGQTWCSLRATLQRMQLGEFSGTAGQVRQRTETTPAQKQIFKALAVKEPPLLFSINPTAKKNA
>NC_018870.1|WP_015051476.1|2464856_2465594_-|CRISPR-associated-endoribonuclease-Cas6
MRLIVEFRATENERITLPLQYNKAVQGMIYQRVREHLPELHDRGFVSAGRVFRLFVFSRIEGSGVKIINGMISFNSPVRIKIGSPNNNFLECLANSLLRTPQIDIGGSPLVVESVAIARNPDFSSGRVKVRAISPITVYSTLMSADGRKKTYYYHPEEKEFSDQIRNNIIKKGALLGVDDKEAYFTIEPYRVRNTDLKTVYYKDYVVKGWLGQYLLRGTPELLNIAYDAGIGAKNSQGFGMVEII
>NC_018870.1|WP_015051477.1|2465607_2465871_-|CRISPR-associated-endonuclease-Cas2
MFVIEVYDVNEKRVAKVLKVSRKYLYWVQNSVLEGEISEANFRRLKEELLEIIDLKEDSLIFYTFRTTKYSERQCFGVLKGGEETIF
>NC_018870.1|WP_015051478.1|2465873_2466866_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MRKSIYLLNSGELRRENNTICLITDEGKRFLPVEDIGEIHVFGEVDLNKRLLEFLSEKEIILHYYNHYDYYMGSFYPREHFNSGYMTVKQAEHYINPELRICLARAFVTGAVKNIRQVLMYYRNRGKEVGSAFERIEKLMGEIDSASSVDELMAYEGNIRDAYYGTFDLIIDNPDYVFEVRSKRPPKNRLNALISFGNTLLYTTTLSEIYRTHLDPRIGYLHTSNFRRFSLNLDVAEIFKPILVDRLIFYLTGKQMLKKSHFEKKLDGVVLSRSGRTLFIQNFEQRMMSTIKHRELGRQVSYRRLIRMELYKLEKHLMGEADYQPFVARW

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Crispr_ID: NC_018870_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018870_6

2443574-2446006

Unclear

Consensus_repeat	Method
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CRT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	PILER-CR
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CRISPRCasFinder

36 spacers

cas6,cas2,cas1,cas4,cas3

The CRISPR arrays of NC_018870_6

>merge|NC_018870|6|2443574-2446006|CRT,PILER-CR,CRISPRCasFinder
GCTAATTTTCAGGGCAGGTACGCTGAGAACATAATATTCCTTGTATGCATAAACCACGCCGTCAGGAGTTTCAATTCCTCATAGGTACGCTGAGAACTCTGCACATTGGGGGCATAAAGCGACGCCCCCAAAACCGTTTCAATTCCTCATAGGTACGCTGAGAACTTCTGTGTCGAAGTCAGTTCCCCTGAGCAGTCCCTGGTTTCAATTCCTCATAGGTACGCTGAGAACGGAAAGAAAAACATGAGAAGGTTAAGATGCAAAAGTGTTTCAATTCCTCATAGGTACGCTGAGAACTCGAAACGTCGCACGAATCTGTCGCTATCCTTAGAAGTTTCAATTCCTCATAGGTACGCTGAGAACGCATAAATATCCGAGGTGGTGCTTGCCCGCTCATGGCCGTTTCAATTCCTCATAGGTACTCTGAGAACAATGCTGGCAAGGTCGTTCTCGCCTGGGCTATGCAGTGTTTCAATTCCTCATAGGTACGCTGAGAACTGAGTTGATAGAACAAATAAAGAGTATGTATGGGAAGGGTTTCAATTCCTCATAGGTACGCTGAGAACTATGCCAGTTTAGGCGAAACGGTATATCACAGATAGTTTCAATTCCTCATAGGTACGCTGAGAACATTTATCATCTTATTGCGGAATGCAATTATGGCACAAGTTTCAATTCCTCATAGGTACGCTGAGAACGGTTGTAATGAGAGCCGGGGAATTGAGGCACCGGGGTTTCAATTCCTCATAGGTACGCTGAGAACCCATCCCCCCCGCGCGGAAGGCGAAGCCGCTGCGTTGGTTTCAATTCCTCATAGGTACGCTGAGAACATTGCCCTGGCGCTGAAGCTGAGCGTGAAAGATGGAGAGTTTCAATTCCTCATAGGTACGCTGAGAACCCGTAGGGATGTGGCTCGGCAGATACAAGAACACTCGTTTCAATTCCTCATAGGTACGCTGAGAACTTCAATTTGGCGATTGGGAGTTTTGGGATGATGAAGAGTTTCAATTCCTCATAGGTACGCTGAGAACCCCCTAAAACTCTATTCAACGTAGTGAGCAAACCTGTTTCAATTCCTCATAGGTACGCTGAGAACGGTGCACACTGCCACTGTAATCGTTGGCATTGTTGGTTTCAATTCCTCATAGGTACGCTGAGAACGCGGTGTACGAGCGTCATCTCTTTGTTAGCCTGGGTTTCAATTCCTCATAGGTACGCTGAGAACCAAGTTTTTCTCCCGCTTCACCAGCTGGCCGCCCAGGGTTTCAATTCCTCATAGGTACGCTGAGAACCCCCAGCTTTTGGTCGGGCACGAATGCTTGACCATGTTTCAATTCCTCATAGGTACGCTGAGAACGTGCGGACTTCCTCACCATTAACCGTATCCCAGCTCGCGTGTTTCAATTCCTCATAGGTACGCTGAGAACTTTCAAGAATCTCCATTGCCGCCGCTATGTCGGTGGAGGTTTCAATTCCTCATAGGTACGCTGAGAACGCGGTTTTTGCTTCATTATATACGCATTTTGGCCGGGGTTTCAATTCCTCATAGGTACGCTGAGAACGCGGTGTACGAGCGTCATCTCTTTGTTAGCCTGGGTTTCAATTCCTCATAGGTACGCTGAGAACGACTGGAAGAGGGGGAGCCTAAACAGGCTCTCCCTTAGTTTCAATTCCTCATAGGTACGCTGAGAACGACTGGAAGAGGGGGAGCCTAAACAGGCTCTCCCTTAGTTTCAATTCCTCATAGGTACGCTGAGAACGCGAATAATAATCATGGAACTTACCTCTTTGCTTCAGTTTCAATTCCTCATAGGTACGCTGAGAACCTATACCGGTCGCAATAGCCTTAGCAGCCTTGTCCTGCGTTTCAATTCCTCATAGGTACGCTGAAAACGGATACCTGGTCACCGGCGCCGGCAGTTTCTTTCCTAGAGTTTCAATTCCTCATAGGTACGCTGAAAACAGGAATATCCCGTGTTGCGTCTCCGCCGATGTAAATGGTTTCAATTCCTCATAGGTACGCTGAAAACGCAAATGCTTGAAAGGATTTTTCCGGTGGTGCGTGTTTCAATTCCTCATAGGTACGCTGAAAACGGTGAGAATACTTCGCTACCTACACCAACAAGGTATCGTTTCAATTCCTCATAGGTACGCTGAAAACCCGTCAGGATAAAGATACAAATTACCGCTTGTTATCCTGAGTTTCAATTCCTCATAGGTACGCTGAAAACGTCAGGATGTATGGAACAATGCACAAGCAGTATATGTGTTTCAATTCCTCATAGGTACGCTGAAAACGATAGTTTCCTCGGGGAGTGCCTTCCCGCAATGCGGGGTTTCAATTCCTCATAGGTACGCTGAAAACTTCTCGGCTGGCAGGCTGATTTAGAGGAGGTGTTCTAAGTTTCAATTCCTCATACCGGAGTTCGACAG

>NC_018870|6|5|2443574-2446006|CRT
GCTAATTTTCAGGGCAGGTACGCTGAGAAC	ATAATATTCCTTGTATGCATAAACCACGCCGTCAGGA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TCTGCACATTGGGGGCATAAAGCGACGCCCCCAAAACC
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TTCTGTGTCGAAGTCAGTTCCCCTGAGCAGTCCCTG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GGAAAGAAAAACATGAGAAGGTTAAGATGCAAAAGT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TCGAAACGTCGCACGAATCTGTCGCTATCCTTAGAA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCATAAATATCCGAGGTGGTGCTTGCCCGCTCATGGCC
GTTTCAATTCCTCATAGGTACTCTGAGAAC	AATGCTGGCAAGGTCGTTCTCGCCTGGGCTATGCAGT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TGAGTTGATAGAACAAATAAAGAGTATGTATGGGAAGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TATGCCAGTTTAGGCGAAACGGTATATCACAGATA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	ATTTATCATCTTATTGCGGAATGCAATTATGGCACAA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GGTTGTAATGAGAGCCGGGGAATTGAGGCACCGGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CCATCCCCCCCGCGCGGAAGGCGAAGCCGCTGCGTTG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	ATTGCCCTGGCGCTGAAGCTGAGCGTGAAAGATGGAGA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CCGTAGGGATGTGGCTCGGCAGATACAAGAACACTC
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TTCAATTTGGCGATTGGGAGTTTTGGGATGATGAAGA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CCCCTAAAACTCTATTCAACGTAGTGAGCAAACCT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GGTGCACACTGCCACTGTAATCGTTGGCATTGTTG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCGGTGTACGAGCGTCATCTCTTTGTTAGCCTGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CAAGTTTTTCTCCCGCTTCACCAGCTGGCCGCCCAGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CCCCAGCTTTTGGTCGGGCACGAATGCTTGACCAT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GTGCGGACTTCCTCACCATTAACCGTATCCCAGCTCGCGT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TTTCAAGAATCTCCATTGCCGCCGCTATGTCGGTGGAG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCGGTTTTTGCTTCATTATATACGCATTTTGGCCGGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCGGTGTACGAGCGTCATCTCTTTGTTAGCCTGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GACTGGAAGAGGGGGAGCCTAAACAGGCTCTCCCTTA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GACTGGAAGAGGGGGAGCCTAAACAGGCTCTCCCTTA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCGAATAATAATCATGGAACTTACCTCTTTGCTTCA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CTATACCGGTCGCAATAGCCTTAGCAGCCTTGTCCTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGATACCTGGTCACCGGCGCCGGCAGTTTCTTTCCTAGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGGAATATCCCGTGTTGCGTCTCCGCCGATGTAAATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCAAATGCTTGAAAGGATTTTTCCGGTGGTGCGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGTGAGAATACTTCGCTACCTACACCAACAAGGTATC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCGTCAGGATAAAGATACAAATTACCGCTTGTTATCCTGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTCAGGATGTATGGAACAATGCACAAGCAGTATATGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GATAGTTTCCTCGGGGAGTGCCTTCCCGCAATGCGGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTCTCGGCTGGCAGGCTGATTTAGAGGAGGTGTTCTAA
GTTTCAATTCCTCATACCGGAGTTCGACAG

>NC_018870|6|6|2443641-2445938|PILER-CR
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TCTGCACATTGGGGGCATAAAGCGACGCCCCCAAAACC
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TTCTGTGTCGAAGTCAGTTCCCCTGAGCAGTCCCTG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GGAAAGAAAAACATGAGAAGGTTAAGATGCAAAAGT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TCGAAACGTCGCACGAATCTGTCGCTATCCTTAGAA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCATAAATATCCGAGGTGGTGCTTGCCCGCTCATGGCC
GTTTCAATTCCTCATAGGTACTCTGAGAAC	AATGCTGGCAAGGTCGTTCTCGCCTGGGCTATGCAGT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TGAGTTGATAGAACAAATAAAGAGTATGTATGGGAAGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TATGCCAGTTTAGGCGAAACGGTATATCACAGATA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	ATTTATCATCTTATTGCGGAATGCAATTATGGCACAA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GGTTGTAATGAGAGCCGGGGAATTGAGGCACCGGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CCATCCCCCCCGCGCGGAAGGCGAAGCCGCTGCGTTG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	ATTGCCCTGGCGCTGAAGCTGAGCGTGAAAGATGGAGA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CCGTAGGGATGTGGCTCGGCAGATACAAGAACACTC
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TTCAATTTGGCGATTGGGAGTTTTGGGATGATGAAGA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CCCCTAAAACTCTATTCAACGTAGTGAGCAAACCT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GGTGCACACTGCCACTGTAATCGTTGGCATTGTTG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCGGTGTACGAGCGTCATCTCTTTGTTAGCCTGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CAAGTTTTTCTCCCGCTTCACCAGCTGGCCGCCCAGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CCCCAGCTTTTGGTCGGGCACGAATGCTTGACCAT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GTGCGGACTTCCTCACCATTAACCGTATCCCAGCTCGCGT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TTTCAAGAATCTCCATTGCCGCCGCTATGTCGGTGGAG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCGGTTTTTGCTTCATTATATACGCATTTTGGCCGGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCGGTGTACGAGCGTCATCTCTTTGTTAGCCTGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GACTGGAAGAGGGGGAGCCTAAACAGGCTCTCCCTTA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GACTGGAAGAGGGGGAGCCTAAACAGGCTCTCCCTTA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCGAATAATAATCATGGAACTTACCTCTTTGCTTCA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CTATACCGGTCGCAATAGCCTTAGCAGCCTTGTCCTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGATACCTGGTCACCGGCGCCGGCAGTTTCTTTCCTAGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGGAATATCCCGTGTTGCGTCTCCGCCGATGTAAATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCAAATGCTTGAAAGGATTTTTCCGGTGGTGCGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGTGAGAATACTTCGCTACCTACACCAACAAGGTATC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCGTCAGGATAAAGATACAAATTACCGCTTGTTATCCTGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTCAGGATGTATGGAACAATGCACAAGCAGTATATGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GATAGTTTCCTCGGGGAGTGCCTTCCCGCAATGCGGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC

>NC_018870|6|6|2443641-2445938|CRISPRCasFinder
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TCTGCACATTGGGGGCATAAAGCGACGCCCCCAAAACC
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TTCTGTGTCGAAGTCAGTTCCCCTGAGCAGTCCCTG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GGAAAGAAAAACATGAGAAGGTTAAGATGCAAAAGT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TCGAAACGTCGCACGAATCTGTCGCTATCCTTAGAA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCATAAATATCCGAGGTGGTGCTTGCCCGCTCATGGCC
GTTTCAATTCCTCATAGGTACTCTGAGAAC	AATGCTGGCAAGGTCGTTCTCGCCTGGGCTATGCAGT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TGAGTTGATAGAACAAATAAAGAGTATGTATGGGAAGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TATGCCAGTTTAGGCGAAACGGTATATCACAGATA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	ATTTATCATCTTATTGCGGAATGCAATTATGGCACAA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GGTTGTAATGAGAGCCGGGGAATTGAGGCACCGGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CCATCCCCCCCGCGCGGAAGGCGAAGCCGCTGCGTTG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	ATTGCCCTGGCGCTGAAGCTGAGCGTGAAAGATGGAGA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CCGTAGGGATGTGGCTCGGCAGATACAAGAACACTC
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TTCAATTTGGCGATTGGGAGTTTTGGGATGATGAAGA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CCCCTAAAACTCTATTCAACGTAGTGAGCAAACCT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GGTGCACACTGCCACTGTAATCGTTGGCATTGTTG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCGGTGTACGAGCGTCATCTCTTTGTTAGCCTGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CAAGTTTTTCTCCCGCTTCACCAGCTGGCCGCCCAGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CCCCAGCTTTTGGTCGGGCACGAATGCTTGACCAT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GTGCGGACTTCCTCACCATTAACCGTATCCCAGCTCGCGT
GTTTCAATTCCTCATAGGTACGCTGAGAAC	TTTCAAGAATCTCCATTGCCGCCGCTATGTCGGTGGAG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCGGTTTTTGCTTCATTATATACGCATTTTGGCCGGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCGGTGTACGAGCGTCATCTCTTTGTTAGCCTGG
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GACTGGAAGAGGGGGAGCCTAAACAGGCTCTCCCTTA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GACTGGAAGAGGGGGAGCCTAAACAGGCTCTCCCTTA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	GCGAATAATAATCATGGAACTTACCTCTTTGCTTCA
GTTTCAATTCCTCATAGGTACGCTGAGAAC	CTATACCGGTCGCAATAGCCTTAGCAGCCTTGTCCTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGATACCTGGTCACCGGCGCCGGCAGTTTCTTTCCTAGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGGAATATCCCGTGTTGCGTCTCCGCCGATGTAAATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCAAATGCTTGAAAGGATTTTTCCGGTGGTGCGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGTGAGAATACTTCGCTACCTACACCAACAAGGTATC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCGTCAGGATAAAGATACAAATTACCGCTTGTTATCCTGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTCAGGATGTATGGAACAATGCACAAGCAGTATATGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GATAGTTTCCTCGGGGAGTGCCTTCCCGCAATGCGGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018870.1\|WP_015051470.1\|2438417_2439062_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|379098
NC_018870.1\|WP_015051476.1\|2464856_2465594_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NC_018870.1\|WP_015051469.1\|2438070_2438394_+\|transposase	unknown	unknown	gnl\|CDD\|366690
NC_018870.1\|WP_015049782.1\|2453138_2453459_-\|IS66-family-insertion-sequence-hypothetical-protein	unknown	unknown	gnl\|CDD\|225511
NC_018870.1\|WP_015051465.1\|2436159_2436408_-\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_037999167.1\|2466877_2467384_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_018870.1\|WP_081578676.1\|2458292_2459963_+\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_018870.1\|WP_015051464.1\|2435818_2436160_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NC_018870.1\|WP_148275911.1\|2436557_2436800_+\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015051472.1\|2448405_2449620_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018870.1\|WP_015051480.1\|2467373_2469641_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_018870.1\|WP_081578676.1\|2446079_2447750_-\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_018870.1\|WP_015051478.1\|2465873_2466866_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_018870.1\|WP_015051477.1\|2465607_2465871_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_018870.1\|WP_015051468.1\|2437832_2438030_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275209
NC_018870.1\|WP_015051475.1\|2452788_2453145_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NC_018870.1\|WP_015051471.1\|2440644_2441883_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376773
NC_018870.1\|WP_148276018.1\|2437231_2437552_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372110
NC_018870.1\|WP_015051472.1\|2442275_2443490_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018870.1\|WP_037999814.1\|2436950_2437226_+\|BrnT-family-toxin	unknown	unknown	gnl\|CDD\|225481

Protein	Function_ID	Function_description	E-value
NC_018870.1\|WP_015051476.1\|2464856_2465594_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.60943e-42
NC_018870.1\|WP_015051469.1\|2438070_2438394_+\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	1.36302e-09
NC_018870.1\|WP_015049782.1\|2453138_2453459_-\|IS66-family-insertion-sequence-hypothetical-protein	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.000769281
NC_018870.1\|WP_037999167.1\|2466877_2467384_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.89318e-70
NC_018870.1\|WP_081578676.1\|2458292_2459963_+\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.8014e-28
NC_018870.1\|WP_015051464.1\|2435818_2436160_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	2.59884e-33
NC_018870.1\|WP_015051471.1\|2440644_2441883_-\|IS110-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	5.273e-26
NC_018870.1\|WP_015051472.1\|2448405_2449620_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.31767e-41
NC_018870.1\|WP_015051480.1\|2467373_2469641_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	3.72763e-54
NC_018870.1\|WP_081578676.1\|2446079_2447750_-\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.8014e-28
NC_018870.1\|WP_015051478.1\|2465873_2466866_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	8.78104e-171
NC_018870.1\|WP_015051477.1\|2465607_2465871_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.43479e-28
NC_018870.1\|WP_015051468.1\|2437832_2438030_+\|hypothetical-protein	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	4.96046e-15
NC_018870.1\|WP_015051475.1\|2452788_2453145_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	1.30076e-55
NC_018870.1\|WP_015051470.1\|2438417_2439062_+\|IS3-family-transposase	gnl\|CDD\|379098	pfam13276, HTH_21, HTH-like domain. This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.	7.64926e-08
NC_018870.1\|WP_148276018.1\|2437231_2437552_+\|hypothetical-protein	gnl\|CDD\|372110	pfam12441, CopG_antitoxin, CopG antitoxin of type II toxin-antitoxin system. CopG antitoxin is a member of a type II toxin-antitoxin system family found in bacteria and archaea. Most antitoxins encoded by the relBE and parDE loci belong to the MetJ/Arc/CopG family of dimeric proteins which bind DNA through N-terminal ribbon-helix-helix (RHH) motifs. The toxin for CopG proteins falls into the family BrnT_toxin, pfam04365.	8.50953e-11
NC_018870.1\|WP_015051472.1\|2442275_2443490_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.31767e-41
NC_018870.1\|WP_037999814.1\|2436950_2437226_+\|BrnT-family-toxin	gnl\|CDD\|225481	COG2929, COG2929, Uncharacterized protein conserved in bacteria [Function unknown].	3.61785e-09

>NC_018870.1|WP_015051472.1|2442275_2443490_+|IS110-family-transposase
MDVVFPYCCGLDVHKNSVVACVITPDEKEIRTFGTMTRDLLNLADWLTSKGCTHVAMESTGVYWKPIYNILEQYQLELLVVNAKHIKAVPGRKTDVKDAEWIADLLRHGLLKGSYIPDREQRELRELVGYRKSLVEERAREVNRIQKTLEGAGIKLSSVATDVVGVSGRAMIEGIISGIDDPAVLADFAQKKLKKKKEQLEQALFGLVGKHQRLLLAAQLRHIDYLDQEIARLDQQIEERMRPFEAELALLDTIPGVGRRTSQVILACIGADMSRFPSAAHLSSWAGVAPGNNESAGKRKSGKTTKGNTLLHTTLIQAARAASRTKNTYLSALYHRVAARRGANRAAVAVAHSILVSVYYMLIRRVPYHDLGGDYFEKRNSKAVVNRAVKQLEQLGYRVSIEVA
>NC_018870.1|WP_015051471.1|2440644_2441883_-|IS110-family-transposase
MKLFVGIDVSMKDFKARMFDAEGEEIAKRMRYKNDDPGAESFVKYLVEICGANEVDSLRIGMESTSVYGWHLQMRLAGEPLLASFHPQVYVFNPKVIANFRKQYVDIPKDDWFDCLVIADRLRFGRLPESCQVDFRYLPLQRLTRFRYHLIQTITREKNYFLTNLFLKFNTICQDKVLSDIFGATSEAILTEFLSPEEIAARPLDELIDFLMEKGKSHFSNPEATAKALKHAAACAYRLHGSLLEPVNLILATSLQTICTLEQQVKSIDRAIEKELSHFPNTLQSMPGMGPVCTAGIIAEIGDIHRFDNEKAVAKFAGLTWRKHQSGEFEADDTPLTKTGNVYLRYYFVMAADSVRKWDPRFAEFYARKFKESSTHHHRRALVLTARKLVRVVDALLRSNQLYVPQGQRKVV
>NC_018870.1|WP_015051470.1|2438417_2439062_+|IS3-family-transposase
MGYKVSLVLRIIGISRSTYYPNLKRQPKPRIFAGGRPKSHYTFTSDNKVVSNEQVKEWLCELITAEGFAYGYLKLTHCLRRKFHLIINKKKVYRLCKELDILRPQRKIKRKHPRRLARNRVITASNQLWEADLKYGYIAGEDRFFFIMPIIDVFDRCIVAYHIGLSCEAKDARVMSLPAMPKRMQRLSTSSTFTTKPGFIQQLNTYHRWNAINC
>NC_018870.1|WP_015051469.1|2438070_2438394_+|transposase
MNRKQYSPEMKMQIVKETLETGNASIVARRHDIAPSLVARWARCYKRYGTFYPQKEVPGTNGSCIPPDYKKITKENEQLKKLLGEKDLEIAILRDLLKKTNLPFPIK
>NC_018870.1|WP_015051468.1|2437832_2438030_+|hypothetical-protein
MEKVLERSNMLRALRRVKSNKGADGVDGMEIKSLRPYLKEHWPKIKEELLKGTYKLFSPLTRLNS
>NC_018870.1|WP_148276018.1|2437231_2437552_+|hypothetical-protein
MAKKKELPEFKGDEIPEFASEEEAAEFFDRHSFAEAMERGVLAPDDPAEPDPELAATSKTKRVTLRLRVSQIEAAKEIAKRKDIPYQTLLRSWIAEGIRREMEGKG
>NC_018870.1|WP_037999814.1|2436950_2437226_+|BrnT-family-toxin
MAKAKRFEWDSRNVNHIARHNVKPEEVEEVFLSRPLIRKARSGLKVAMGRTDAGHYLFVVFALKSSDVIRVITARDMSTSERRYYRRERGE
>NC_018870.1|WP_148275911.1|2436557_2436800_+|hypothetical-protein
MSDVVEKPTGGSFPSDLKLGTTTWCPYCGGVKGFVWDTDAFTSRYPNCGVSTEDSYVCVCSSGPVKGGRASTRVSASTPP
>NC_018870.1|WP_015051465.1|2436159_2436408_-|hypothetical-protein
MPSTVRVSNRAWKALKEIAEQTGETMQGVLERAVEAYRRQWLLERANKAYAALRSDPEKWDEEVAERREWEAPLADGLEGSE
>NC_018870.1|WP_015051464.1|2435818_2436160_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MASPLRGEVWLVDLDPVRGHEQAGKRPALVISVDAFNTGPAGLVIVLPMTSKDKGIPLHVKVDPPEGGVKATSFVKCEDIRSVSTEKLVAKLGRVSAEAMILVEDRVRILVGL
>NC_018870.1|WP_081578676.1|2446079_2447750_-|IS1634-family-transposase
MWYNVDMYIRTIQRKNKDGSVVRYIQLAHNQWDPQARCAKAKVLFNFGREEEVDREALKRLVKSINRFLGPGETLRYEAETGAAPLKFITSRPLGGAWVLDRLWEELGIKGVLETLLKKRQYKTPVERAIFAMAANRALDPMSKRGVEEWVKEDAVIPGVEEIPLQQLYRAMDFLLENEAELQKQVYYSVANLLNLEVDILYFDTTSTYFEIEDEDEDGGLRRRGHSKDHRPDLPQAVIGLAVTRDGIPVRCWVWPGNTADISVVEQVKKDLIGWKLGRVITVLDRGFNSEDNLRCLQRAGGHYIAGEKLRSGKENTVQALKRGGRYQTVRDNLEVKEIVVGNGEARERYILVRNPEEAARDKARREKIIKELEEQLPHIKTHAKAVCELMAHPVYGRYLKLDSRSLPKIDRAKIREEEKLDGKYLLRTSDDTLSAEDVALGYKQLLLVEDAFRTLKSRLELRPVYHRLEDRIRSHVLLCWLALLLIRIAENRTGQTWCSLRATLQRMQLGEFSGTAGQVRQRTETTPAQKQIFKALAVKEPPLLFSINPTAKKNA
>NC_018870.1|WP_015051472.1|2448405_2449620_+|IS110-family-transposase
MDVVFPYCCGLDVHKNSVVACVITPDEKEIRTFGTMTRDLLNLADWLTSKGCTHVAMESTGVYWKPIYNILEQYQLELLVVNAKHIKAVPGRKTDVKDAEWIADLLRHGLLKGSYIPDREQRELRELVGYRKSLVEERAREVNRIQKTLEGAGIKLSSVATDVVGVSGRAMIEGIISGIDDPAVLADFAQKKLKKKKEQLEQALFGLVGKHQRLLLAAQLRHIDYLDQEIARLDQQIEERMRPFEAELALLDTIPGVGRRTSQVILACIGADMSRFPSAAHLSSWAGVAPGNNESAGKRKSGKTTKGNTLLHTTLIQAARAASRTKNTYLSALYHRVAARRGANRAAVAVAHSILVSVYYMLIRRVPYHDLGGDYFEKRNSKAVVNRAVKQLEQLGYRVSIEVA
>NC_018870.1|WP_015051475.1|2452788_2453145_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MLNEAGIDRVYLACGATDLRKSIDGLAVLVKEGFELDPFSSCLFVFCNRKRDKLKILHWEHNGFWLYYRRLEKGKFIWPQDTTSSTITISRRELRWLLDGLPLKQPKAHPEVKARTIL
>NC_018870.1|WP_015049782.1|2453138_2453459_-|IS66-family-insertion-sequence-hypothetical-protein
MTRAELQKLWEARIAEYRESGQSVKEWCASHEGINPRQLWYWLRKFKNQTPAPPEISNRWLSVEISEEDSLEQALLVKIGPASIEVRPGFDPALLTKVVQVLMALC
>NC_018870.1|WP_081578676.1|2458292_2459963_+|IS1634-family-transposase
MWYNVDMYIRTIQRKNKDGSVVRYIQLAHNQWDPQARCAKAKVLFNFGREEEVDREALKRLVKSINRFLGPGETLRYEAETGAAPLKFITSRPLGGAWVLDRLWEELGIKGVLETLLKKRQYKTPVERAIFAMAANRALDPMSKRGVEEWVKEDAVIPGVEEIPLQQLYRAMDFLLENEAELQKQVYYSVANLLNLEVDILYFDTTSTYFEIEDEDEDGGLRRRGHSKDHRPDLPQAVIGLAVTRDGIPVRCWVWPGNTADISVVEQVKKDLIGWKLGRVITVLDRGFNSEDNLRCLQRAGGHYIAGEKLRSGKENTVQALKRGGRYQTVRDNLEVKEIVVGNGEARERYILVRNPEEAARDKARREKIIKELEEQLPHIKTHAKAVCELMAHPVYGRYLKLDSRSLPKIDRAKIREEEKLDGKYLLRTSDDTLSAEDVALGYKQLLLVEDAFRTLKSRLELRPVYHRLEDRIRSHVLLCWLALLLIRIAENRTGQTWCSLRATLQRMQLGEFSGTAGQVRQRTETTPAQKQIFKALAVKEPPLLFSINPTAKKNA
>NC_018870.1|WP_015051476.1|2464856_2465594_-|CRISPR-associated-endoribonuclease-Cas6
MRLIVEFRATENERITLPLQYNKAVQGMIYQRVREHLPELHDRGFVSAGRVFRLFVFSRIEGSGVKIINGMISFNSPVRIKIGSPNNNFLECLANSLLRTPQIDIGGSPLVVESVAIARNPDFSSGRVKVRAISPITVYSTLMSADGRKKTYYYHPEEKEFSDQIRNNIIKKGALLGVDDKEAYFTIEPYRVRNTDLKTVYYKDYVVKGWLGQYLLRGTPELLNIAYDAGIGAKNSQGFGMVEII
>NC_018870.1|WP_015051477.1|2465607_2465871_-|CRISPR-associated-endonuclease-Cas2
MFVIEVYDVNEKRVAKVLKVSRKYLYWVQNSVLEGEISEANFRRLKEELLEIIDLKEDSLIFYTFRTTKYSERQCFGVLKGGEETIF
>NC_018870.1|WP_015051478.1|2465873_2466866_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MRKSIYLLNSGELRRENNTICLITDEGKRFLPVEDIGEIHVFGEVDLNKRLLEFLSEKEIILHYYNHYDYYMGSFYPREHFNSGYMTVKQAEHYINPELRICLARAFVTGAVKNIRQVLMYYRNRGKEVGSAFERIEKLMGEIDSASSVDELMAYEGNIRDAYYGTFDLIIDNPDYVFEVRSKRPPKNRLNALISFGNTLLYTTTLSEIYRTHLDPRIGYLHTSNFRRFSLNLDVAEIFKPILVDRLIFYLTGKQMLKKSHFEKKLDGVVLSRSGRTLFIQNFEQRMMSTIKHRELGRQVSYRRLIRMELYKLEKHLMGEADYQPFVARW
>NC_018870.1|WP_037999167.1|2466877_2467384_-|CRISPR-associated-protein-Cas4
MIGEHWPVNGTLVWYYTICHRQVWLMARQLTPDEDDDNVAIGRFIHEHSYRRDRHELAVGNIRIDLMQASRDEVLIAEIKKSSRFLESARLQLKYYLFVLKSLGLDFKGVLLVPEERKRELVTLEEEDLVEIERIIGEIRRIIDSPVPPPAVRTRWCRPCAYAEFCWA
>NC_018870.1|WP_015051480.1|2467373_2469641_-|CRISPR-associated-helicase/endonuclease-Cas3
MSPGEVYSHKGKRLEQHLLETAELAQKIARHFRLELEEGERWALLLHDLAKAHPLFQKHLLQQKGRFGHAAPSAALVLGLTGDLLCTEAVRRHHSSLENLDEAKKFWFCWDYQENACGVIGKIPVWNGAEAVMEALGHQLAKWGELLPAQADWDELIFERVEFFPPDEEKMEEAWLRLRMLYSLLVTADRYNAAVGREMEYHPLRIDQKRVEDFAASLRGRPLAEWRQQVREEVVRKAEEVLKKPGIYTLTLPTGAGKTLVGLELAMLAAERFAATGIIYVLPFISLVEQNADVARVLFKDASPVREDHYLSEVAGEEGDPENSSPQERFLSFFRYWQEPVVITTMAKFWEVLYSPKGNDTMSLHRLSRAVVILDEPQAIPSCYWQGFGKTLNLLSEKLNTTFILMTATQPEIAQGLELAPRPYFFPMIRHRFEWRRERLTVPELLGSPDVISKLLAKSALLVFNTHRSALLAYLELQSRGVTSYFLSGWVTPLDRRATLQQIREDESAGKPARLVSTQVVEAGVDLDFQFVYRDLGPLDSIIQVAGRCNRHGKREQGEVLVCELCDENGRSYAGYVYDSTLLVATKAVLKDSFDERDCPGMVAAYYRKVREITAENPLWEDISSGRWGEFHDLIEKEERGEATLVVAYEGVENDLDLLSRQAAPDEDVMRMVEQKREASRRLGLHAVSVPVKMLEEWLLRVGGMIYGAESGDILRKVSSGIYLVQGEGIGRIYSRRTGFMPPDLEAAGDGVDDW

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Crispr_ID: NC_018870_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018870_7

2447887-2448107

Unclear

Consensus_repeat	Method
TTGTTTCAATTCCTCATAGGTACGCTGAAAACC	CRT
TGTTTCAATTCCTCATAGGTACGCTGAAAACC	PILER-CR

3 spacers

cas6,cas2,cas1,cas4,cas3,cas5

The CRISPR arrays of NC_018870_7

>merge|NC_018870|7|2447887-2448107|CRT,PILER-CR
TGTCGAACTCCGGTCATAGGTACGCTGAAAACCGGTAGATAGTGCCGACGAGGCTCTTGTTTCAATTCCTCATAGGTACGCTGAAAACCGATATTGTTCAAACTTTGCATTCATTTCGTTCCTGTTTCAATTCCTCATAGGTACGCTGAAAACCCATGTACTTCATAATATCATCGAAGAACGTTTCTTTGTTTCAATTCCTCATAGGTACGCTGAAAACG

>NC_018870|7|6|2447887-2448107|CRT
TGTCGAACTCCGGTCATAGGTACGCTGAAAACC	GGTAGATAGTGCCGACGAGGCTC
TTGTTTCAATTCCTCATAGGTACGCTGAAAACC	GATATTGTTCAAACTTTGCATTCATTTCGTTC
CTGTTTCAATTCCTCATAGGTACGCTGAAAACC	CATGTACTTCATAATATCATCGAAGAACGTTTCT
TTGTTTCAATTCCTCATAGGTACGCTGAAAACG

>NC_018870|7|7|2447944-2448107|PILER-CR
TGTTTCAATTCCTCATAGGTACGCTGAAAACC	GATATTGTTCAAACTTTGCATTCATTTCGTTCC
TGTTTCAATTCCTCATAGGTACGCTGAAAACC	CATGTACTTCATAATATCATCGAAGAACGTTTCTT
TGTTTCAATTCCTCATAGGTACGCTGAAAACG

Protein	Signature genes	Signature genes Name	Protein_function
NC_018870.1\|WP_015051476.1\|2464856_2465594_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NC_018870.1\|WP_015051469.1\|2438070_2438394_+\|transposase	unknown	unknown	gnl\|CDD\|366690
NC_018870.1\|WP_015049782.1\|2453138_2453459_-\|IS66-family-insertion-sequence-hypothetical-protein	unknown	unknown	gnl\|CDD\|225511
NC_018870.1\|WP_015051465.1\|2436159_2436408_-\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_037999167.1\|2466877_2467384_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_018870.1\|WP_081578676.1\|2458292_2459963_+\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_018870.1\|WP_015051471.1\|2440644_2441883_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376773
NC_018870.1\|WP_148275911.1\|2436557_2436800_+\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015051472.1\|2448405_2449620_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018870.1\|WP_015051480.1\|2467373_2469641_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_018870.1\|WP_081578676.1\|2446079_2447750_-\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_018870.1\|WP_015051478.1\|2465873_2466866_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_018870.1\|WP_015051477.1\|2465607_2465871_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_018870.1\|WP_015051468.1\|2437832_2438030_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275209
NC_018870.1\|WP_148276019.1\|2469627_2470320_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_018870.1\|WP_015051475.1\|2452788_2453145_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NC_018870.1\|WP_037999814.1\|2436950_2437226_+\|BrnT-family-toxin	unknown	unknown	gnl\|CDD\|225481
NC_018870.1\|WP_148276018.1\|2437231_2437552_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372110
NC_018870.1\|WP_015051472.1\|2442275_2443490_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018870.1\|WP_015051470.1\|2438417_2439062_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|379098

Protein	Function_ID	Function_description	E-value
NC_018870.1\|WP_015051476.1\|2464856_2465594_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.60943e-42
NC_018870.1\|WP_015051469.1\|2438070_2438394_+\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	1.36302e-09
NC_018870.1\|WP_015051478.1\|2465873_2466866_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	8.78104e-171
NC_018870.1\|WP_081578676.1\|2458292_2459963_+\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.8014e-28
NC_018870.1\|WP_015051471.1\|2440644_2441883_-\|IS110-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	5.273e-26
NC_018870.1\|WP_037999167.1\|2466877_2467384_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.89318e-70
NC_018870.1\|WP_015051472.1\|2448405_2449620_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.31767e-41
NC_018870.1\|WP_015051480.1\|2467373_2469641_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	3.72763e-54
NC_018870.1\|WP_081578676.1\|2446079_2447750_-\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.8014e-28
NC_018870.1\|WP_015051477.1\|2465607_2465871_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.43479e-28
NC_018870.1\|WP_015051468.1\|2437832_2438030_+\|hypothetical-protein	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	4.96046e-15
NC_018870.1\|WP_148276019.1\|2469627_2470320_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	4.95478e-37
NC_018870.1\|WP_015051475.1\|2452788_2453145_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	1.30076e-55
NC_018870.1\|WP_015049782.1\|2453138_2453459_-\|IS66-family-insertion-sequence-hypothetical-protein	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.000769281
NC_018870.1\|WP_037999814.1\|2436950_2437226_+\|BrnT-family-toxin	gnl\|CDD\|225481	COG2929, COG2929, Uncharacterized protein conserved in bacteria [Function unknown].	3.61785e-09
NC_018870.1\|WP_148276018.1\|2437231_2437552_+\|hypothetical-protein	gnl\|CDD\|372110	pfam12441, CopG_antitoxin, CopG antitoxin of type II toxin-antitoxin system. CopG antitoxin is a member of a type II toxin-antitoxin system family found in bacteria and archaea. Most antitoxins encoded by the relBE and parDE loci belong to the MetJ/Arc/CopG family of dimeric proteins which bind DNA through N-terminal ribbon-helix-helix (RHH) motifs. The toxin for CopG proteins falls into the family BrnT_toxin, pfam04365.	8.50953e-11
NC_018870.1\|WP_015051472.1\|2442275_2443490_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.31767e-41
NC_018870.1\|WP_015051470.1\|2438417_2439062_+\|IS3-family-transposase	gnl\|CDD\|379098	pfam13276, HTH_21, HTH-like domain. This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.	7.64926e-08

>NC_018870.1|WP_081578676.1|2446079_2447750_-|IS1634-family-transposase
MWYNVDMYIRTIQRKNKDGSVVRYIQLAHNQWDPQARCAKAKVLFNFGREEEVDREALKRLVKSINRFLGPGETLRYEAETGAAPLKFITSRPLGGAWVLDRLWEELGIKGVLETLLKKRQYKTPVERAIFAMAANRALDPMSKRGVEEWVKEDAVIPGVEEIPLQQLYRAMDFLLENEAELQKQVYYSVANLLNLEVDILYFDTTSTYFEIEDEDEDGGLRRRGHSKDHRPDLPQAVIGLAVTRDGIPVRCWVWPGNTADISVVEQVKKDLIGWKLGRVITVLDRGFNSEDNLRCLQRAGGHYIAGEKLRSGKENTVQALKRGGRYQTVRDNLEVKEIVVGNGEARERYILVRNPEEAARDKARREKIIKELEEQLPHIKTHAKAVCELMAHPVYGRYLKLDSRSLPKIDRAKIREEEKLDGKYLLRTSDDTLSAEDVALGYKQLLLVEDAFRTLKSRLELRPVYHRLEDRIRSHVLLCWLALLLIRIAENRTGQTWCSLRATLQRMQLGEFSGTAGQVRQRTETTPAQKQIFKALAVKEPPLLFSINPTAKKNA
>NC_018870.1|WP_015051472.1|2442275_2443490_+|IS110-family-transposase
MDVVFPYCCGLDVHKNSVVACVITPDEKEIRTFGTMTRDLLNLADWLTSKGCTHVAMESTGVYWKPIYNILEQYQLELLVVNAKHIKAVPGRKTDVKDAEWIADLLRHGLLKGSYIPDREQRELRELVGYRKSLVEERAREVNRIQKTLEGAGIKLSSVATDVVGVSGRAMIEGIISGIDDPAVLADFAQKKLKKKKEQLEQALFGLVGKHQRLLLAAQLRHIDYLDQEIARLDQQIEERMRPFEAELALLDTIPGVGRRTSQVILACIGADMSRFPSAAHLSSWAGVAPGNNESAGKRKSGKTTKGNTLLHTTLIQAARAASRTKNTYLSALYHRVAARRGANRAAVAVAHSILVSVYYMLIRRVPYHDLGGDYFEKRNSKAVVNRAVKQLEQLGYRVSIEVA
>NC_018870.1|WP_015051471.1|2440644_2441883_-|IS110-family-transposase
MKLFVGIDVSMKDFKARMFDAEGEEIAKRMRYKNDDPGAESFVKYLVEICGANEVDSLRIGMESTSVYGWHLQMRLAGEPLLASFHPQVYVFNPKVIANFRKQYVDIPKDDWFDCLVIADRLRFGRLPESCQVDFRYLPLQRLTRFRYHLIQTITREKNYFLTNLFLKFNTICQDKVLSDIFGATSEAILTEFLSPEEIAARPLDELIDFLMEKGKSHFSNPEATAKALKHAAACAYRLHGSLLEPVNLILATSLQTICTLEQQVKSIDRAIEKELSHFPNTLQSMPGMGPVCTAGIIAEIGDIHRFDNEKAVAKFAGLTWRKHQSGEFEADDTPLTKTGNVYLRYYFVMAADSVRKWDPRFAEFYARKFKESSTHHHRRALVLTARKLVRVVDALLRSNQLYVPQGQRKVV
>NC_018870.1|WP_015051470.1|2438417_2439062_+|IS3-family-transposase
MGYKVSLVLRIIGISRSTYYPNLKRQPKPRIFAGGRPKSHYTFTSDNKVVSNEQVKEWLCELITAEGFAYGYLKLTHCLRRKFHLIINKKKVYRLCKELDILRPQRKIKRKHPRRLARNRVITASNQLWEADLKYGYIAGEDRFFFIMPIIDVFDRCIVAYHIGLSCEAKDARVMSLPAMPKRMQRLSTSSTFTTKPGFIQQLNTYHRWNAINC
>NC_018870.1|WP_015051469.1|2438070_2438394_+|transposase
MNRKQYSPEMKMQIVKETLETGNASIVARRHDIAPSLVARWARCYKRYGTFYPQKEVPGTNGSCIPPDYKKITKENEQLKKLLGEKDLEIAILRDLLKKTNLPFPIK
>NC_018870.1|WP_015051468.1|2437832_2438030_+|hypothetical-protein
MEKVLERSNMLRALRRVKSNKGADGVDGMEIKSLRPYLKEHWPKIKEELLKGTYKLFSPLTRLNS
>NC_018870.1|WP_148276018.1|2437231_2437552_+|hypothetical-protein
MAKKKELPEFKGDEIPEFASEEEAAEFFDRHSFAEAMERGVLAPDDPAEPDPELAATSKTKRVTLRLRVSQIEAAKEIAKRKDIPYQTLLRSWIAEGIRREMEGKG
>NC_018870.1|WP_037999814.1|2436950_2437226_+|BrnT-family-toxin
MAKAKRFEWDSRNVNHIARHNVKPEEVEEVFLSRPLIRKARSGLKVAMGRTDAGHYLFVVFALKSSDVIRVITARDMSTSERRYYRRERGE
>NC_018870.1|WP_148275911.1|2436557_2436800_+|hypothetical-protein
MSDVVEKPTGGSFPSDLKLGTTTWCPYCGGVKGFVWDTDAFTSRYPNCGVSTEDSYVCVCSSGPVKGGRASTRVSASTPP
>NC_018870.1|WP_015051465.1|2436159_2436408_-|hypothetical-protein
MPSTVRVSNRAWKALKEIAEQTGETMQGVLERAVEAYRRQWLLERANKAYAALRSDPEKWDEEVAERREWEAPLADGLEGSE
>NC_018870.1|WP_015051472.1|2448405_2449620_+|IS110-family-transposase
MDVVFPYCCGLDVHKNSVVACVITPDEKEIRTFGTMTRDLLNLADWLTSKGCTHVAMESTGVYWKPIYNILEQYQLELLVVNAKHIKAVPGRKTDVKDAEWIADLLRHGLLKGSYIPDREQRELRELVGYRKSLVEERAREVNRIQKTLEGAGIKLSSVATDVVGVSGRAMIEGIISGIDDPAVLADFAQKKLKKKKEQLEQALFGLVGKHQRLLLAAQLRHIDYLDQEIARLDQQIEERMRPFEAELALLDTIPGVGRRTSQVILACIGADMSRFPSAAHLSSWAGVAPGNNESAGKRKSGKTTKGNTLLHTTLIQAARAASRTKNTYLSALYHRVAARRGANRAAVAVAHSILVSVYYMLIRRVPYHDLGGDYFEKRNSKAVVNRAVKQLEQLGYRVSIEVA
>NC_018870.1|WP_015051475.1|2452788_2453145_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MLNEAGIDRVYLACGATDLRKSIDGLAVLVKEGFELDPFSSCLFVFCNRKRDKLKILHWEHNGFWLYYRRLEKGKFIWPQDTTSSTITISRRELRWLLDGLPLKQPKAHPEVKARTIL
>NC_018870.1|WP_015049782.1|2453138_2453459_-|IS66-family-insertion-sequence-hypothetical-protein
MTRAELQKLWEARIAEYRESGQSVKEWCASHEGINPRQLWYWLRKFKNQTPAPPEISNRWLSVEISEEDSLEQALLVKIGPASIEVRPGFDPALLTKVVQVLMALC
>NC_018870.1|WP_081578676.1|2458292_2459963_+|IS1634-family-transposase
MWYNVDMYIRTIQRKNKDGSVVRYIQLAHNQWDPQARCAKAKVLFNFGREEEVDREALKRLVKSINRFLGPGETLRYEAETGAAPLKFITSRPLGGAWVLDRLWEELGIKGVLETLLKKRQYKTPVERAIFAMAANRALDPMSKRGVEEWVKEDAVIPGVEEIPLQQLYRAMDFLLENEAELQKQVYYSVANLLNLEVDILYFDTTSTYFEIEDEDEDGGLRRRGHSKDHRPDLPQAVIGLAVTRDGIPVRCWVWPGNTADISVVEQVKKDLIGWKLGRVITVLDRGFNSEDNLRCLQRAGGHYIAGEKLRSGKENTVQALKRGGRYQTVRDNLEVKEIVVGNGEARERYILVRNPEEAARDKARREKIIKELEEQLPHIKTHAKAVCELMAHPVYGRYLKLDSRSLPKIDRAKIREEEKLDGKYLLRTSDDTLSAEDVALGYKQLLLVEDAFRTLKSRLELRPVYHRLEDRIRSHVLLCWLALLLIRIAENRTGQTWCSLRATLQRMQLGEFSGTAGQVRQRTETTPAQKQIFKALAVKEPPLLFSINPTAKKNA
>NC_018870.1|WP_015051476.1|2464856_2465594_-|CRISPR-associated-endoribonuclease-Cas6
MRLIVEFRATENERITLPLQYNKAVQGMIYQRVREHLPELHDRGFVSAGRVFRLFVFSRIEGSGVKIINGMISFNSPVRIKIGSPNNNFLECLANSLLRTPQIDIGGSPLVVESVAIARNPDFSSGRVKVRAISPITVYSTLMSADGRKKTYYYHPEEKEFSDQIRNNIIKKGALLGVDDKEAYFTIEPYRVRNTDLKTVYYKDYVVKGWLGQYLLRGTPELLNIAYDAGIGAKNSQGFGMVEII
>NC_018870.1|WP_015051477.1|2465607_2465871_-|CRISPR-associated-endonuclease-Cas2
MFVIEVYDVNEKRVAKVLKVSRKYLYWVQNSVLEGEISEANFRRLKEELLEIIDLKEDSLIFYTFRTTKYSERQCFGVLKGGEETIF
>NC_018870.1|WP_015051478.1|2465873_2466866_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MRKSIYLLNSGELRRENNTICLITDEGKRFLPVEDIGEIHVFGEVDLNKRLLEFLSEKEIILHYYNHYDYYMGSFYPREHFNSGYMTVKQAEHYINPELRICLARAFVTGAVKNIRQVLMYYRNRGKEVGSAFERIEKLMGEIDSASSVDELMAYEGNIRDAYYGTFDLIIDNPDYVFEVRSKRPPKNRLNALISFGNTLLYTTTLSEIYRTHLDPRIGYLHTSNFRRFSLNLDVAEIFKPILVDRLIFYLTGKQMLKKSHFEKKLDGVVLSRSGRTLFIQNFEQRMMSTIKHRELGRQVSYRRLIRMELYKLEKHLMGEADYQPFVARW
>NC_018870.1|WP_037999167.1|2466877_2467384_-|CRISPR-associated-protein-Cas4
MIGEHWPVNGTLVWYYTICHRQVWLMARQLTPDEDDDNVAIGRFIHEHSYRRDRHELAVGNIRIDLMQASRDEVLIAEIKKSSRFLESARLQLKYYLFVLKSLGLDFKGVLLVPEERKRELVTLEEEDLVEIERIIGEIRRIIDSPVPPPAVRTRWCRPCAYAEFCWA
>NC_018870.1|WP_015051480.1|2467373_2469641_-|CRISPR-associated-helicase/endonuclease-Cas3
MSPGEVYSHKGKRLEQHLLETAELAQKIARHFRLELEEGERWALLLHDLAKAHPLFQKHLLQQKGRFGHAAPSAALVLGLTGDLLCTEAVRRHHSSLENLDEAKKFWFCWDYQENACGVIGKIPVWNGAEAVMEALGHQLAKWGELLPAQADWDELIFERVEFFPPDEEKMEEAWLRLRMLYSLLVTADRYNAAVGREMEYHPLRIDQKRVEDFAASLRGRPLAEWRQQVREEVVRKAEEVLKKPGIYTLTLPTGAGKTLVGLELAMLAAERFAATGIIYVLPFISLVEQNADVARVLFKDASPVREDHYLSEVAGEEGDPENSSPQERFLSFFRYWQEPVVITTMAKFWEVLYSPKGNDTMSLHRLSRAVVILDEPQAIPSCYWQGFGKTLNLLSEKLNTTFILMTATQPEIAQGLELAPRPYFFPMIRHRFEWRRERLTVPELLGSPDVISKLLAKSALLVFNTHRSALLAYLELQSRGVTSYFLSGWVTPLDRRATLQQIREDESAGKPARLVSTQVVEAGVDLDFQFVYRDLGPLDSIIQVAGRCNRHGKREQGEVLVCELCDENGRSYAGYVYDSTLLVATKAVLKDSFDERDCPGMVAAYYRKVREITAENPLWEDISSGRWGEFHDLIEKEERGEATLVVAYEGVENDLDLLSRQAAPDEDVMRMVEQKREASRRLGLHAVSVPVKMLEEWLLRVGGMIYGAESGDILRKVSSGIYLVQGEGIGRIYSRRTGFMPPDLEAAGDGVDDW
>NC_018870.1|WP_148276019.1|2469627_2470320_-|type-I-B-CRISPR-associated-protein-Cas5
MAMFRKPYTTTSMVSFPFPPPTAVCGLIAAIVGLDHGASEGALKAEYWDRVRGMQVALGLRRPVAWFSTAVNLIKFKSPSGDMGEHIQVKHQLLKRPAYRIYVRGGEVYDELKKRLERQEFIFTPYLGVAFALAEYSYVGEFRETPVEEEAMGIDSVLPLYGDVRLDLQQSGCLHSEVVPFRLDGIRRQQETVNVIYPEYRVNSRIYLRNRGDVEVSLVGTERVAWFEPW

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Crispr_ID: NC_018870_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018870_8

2449704-2451060

Unclear

Consensus_repeat	Method
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CRT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	PILER-CR
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CRISPRCasFinder

20 spacers

cas6,cas2,cas1,cas4,cas3,cas5,cas7

The CRISPR arrays of NC_018870_8

>merge|NC_018870|8|2449704-2451060|CRT,PILER-CR,CRISPRCasFinder
GCTAATTTTCAGGGCAGGTACGCTGAAAACTAAAACTCGTATTCCTTCCCAGTCTTTTTCTTTGGGCAGTTTCAATTCCTCATAGGTACGCTGAAAACACGGAACCACTCCTGCCAATATGCTTCTTTTTCGTTTCGTTTCAATTCCTCATAGGTACGCTGAAAACAGAGCAAAGCAATATCCGGGGGCGTCACATGCTTACAGTTTCAATTCCTCATAGGTACGCTGAAAACCCCGCTTTCGGAGCTACCGGACGAACCGGCGGGATTCGTTTCAATTCCTCATAGGTACGCTGAAAACCCGAAACTGTATAGGAGAGAAGTGCGGGTGTTTCGAGTTTCAATTCCTCATAGGTACGCTGAAAACTCCGGGAAAGAAACGAAGTAATTACTCCCCTTACCGTTTCAATTCCTCATAGGTACGCTGAAAACGAGGAAGCTACCGTTTCGTGTCGTATTATGATTTATTGGTTTCAATTCCTCATAGGTACGCTGAAAACGCATGCCCCGGTAAGTATTATCCGCTGCAGGAGATGTTTCAATTCCTCATAGGTACGCTGAAAACAAAAAGGGAGGAATGCGAAATGAGGAAGAACGTCGCGTTTCAATTCCTCATAGGTACGCTGAAAACGACAAGCACACATTCTTTGCTGTTCTTGAAGAGATGGTTTCAATTCCTCATAGGTACGCTGAAAACAACCAGATTTGGAAGAGGGTGTTGTCCTATCAAAGGTTTCAATTCCTCATAGGTACGCTGAAAACTCCCCGGCCGGCCGGTGCCTGCCGCAAGGATGACGGTTTCAATTCCTCATAGGTACGCTGAAAACTGGAACGACGCAGGCCCGTACTGGCGGATTTCGTAGTTTCAATTCCTCATAGGTACGCTGAAAACAGGAGAATTTTCCTTTGTTTCCCTTGCCCCTGTTCTGTTTCAATTCCTCATAGGTACGCTGAAAACTGGACTACCAAATTTAAATAAGCCATTGCGAGAGAGCAGTTTCAATTCCTCATAGGTACGCTGAAAACAAGAAAGCTCTTGCTACGTTGCATGGAGGCGTTTCGTTTCAATTCCTCATAGGTACGCTGAAAACCTCACTGCGGCGCGATCCGGCGTTATGAGCGGAGGAGTTTCAATTCCTCATAGGTACGCTGAAAACCTTCCTAATGAACCATCCCAATAAACTCACCGTCAAGGTTTCAATTCCTCATAGGTACGCTGAAAACGGAGAGTTTGCTGCTGATATATCGATTGATCTTCATGTTTCAATTCCTCATAGGTACGCTGAAAACCCCGGACAATACCCTCATGATACCGTCCTCGGTTCTTCGTTTCAATTCCTCATAGGTACGCTGAAAAC

>NC_018870|8|7|2449704-2451060|CRT
GCTAATTTTCAGGGCAGGTACGCTGAAAAC	TAAAACTCGTATTCCTTCCCAGTCTTTTTCTTTGGGCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACGGAACCACTCCTGCCAATATGCTTCTTTTTCGTTTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGAGCAAAGCAATATCCGGGGGCGTCACATGCTTACA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCCGCTTTCGGAGCTACCGGACGAACCGGCGGGATTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCGAAACTGTATAGGAGAGAAGTGCGGGTGTTTCGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCCGGGAAAGAAACGAAGTAATTACTCCCCTTACC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAGGAAGCTACCGTTTCGTGTCGTATTATGATTTATTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCATGCCCCGGTAAGTATTATCCGCTGCAGGAGAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAAAAGGGAGGAATGCGAAATGAGGAAGAACGTCGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GACAAGCACACATTCTTTGCTGTTCTTGAAGAGATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AACCAGATTTGGAAGAGGGTGTTGTCCTATCAAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCCCCGGCCGGCCGGTGCCTGCCGCAAGGATGACG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGGAACGACGCAGGCCCGTACTGGCGGATTTCGTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGGAGAATTTTCCTTTGTTTCCCTTGCCCCTGTTCT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGGACTACCAAATTTAAATAAGCCATTGCGAGAGAGCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAGAAAGCTCTTGCTACGTTGCATGGAGGCGTTTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTCACTGCGGCGCGATCCGGCGTTATGAGCGGAGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTTCCTAATGAACCATCCCAATAAACTCACCGTCAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAGAGTTTGCTGCTGATATATCGATTGATCTTCAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCCGGACAATACCCTCATGATACCGTCCTCGGTTCTTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC

>NC_018870|8|8|2449772-2451060|PILER-CR
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACGGAACCACTCCTGCCAATATGCTTCTTTTTCGTTTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGAGCAAAGCAATATCCGGGGGCGTCACATGCTTACA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCCGCTTTCGGAGCTACCGGACGAACCGGCGGGATTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCGAAACTGTATAGGAGAGAAGTGCGGGTGTTTCGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCCGGGAAAGAAACGAAGTAATTACTCCCCTTACC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAGGAAGCTACCGTTTCGTGTCGTATTATGATTTATTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCATGCCCCGGTAAGTATTATCCGCTGCAGGAGAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAAAAGGGAGGAATGCGAAATGAGGAAGAACGTCGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GACAAGCACACATTCTTTGCTGTTCTTGAAGAGATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AACCAGATTTGGAAGAGGGTGTTGTCCTATCAAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCCCCGGCCGGCCGGTGCCTGCCGCAAGGATGACG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGGAACGACGCAGGCCCGTACTGGCGGATTTCGTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGGAGAATTTTCCTTTGTTTCCCTTGCCCCTGTTCT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGGACTACCAAATTTAAATAAGCCATTGCGAGAGAGCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAGAAAGCTCTTGCTACGTTGCATGGAGGCGTTTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTCACTGCGGCGCGATCCGGCGTTATGAGCGGAGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTTCCTAATGAACCATCCCAATAAACTCACCGTCAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAGAGTTTGCTGCTGATATATCGATTGATCTTCAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCCGGACAATACCCTCATGATACCGTCCTCGGTTCTTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC

>NC_018870|8|7|2449772-2451060|CRISPRCasFinder
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACGGAACCACTCCTGCCAATATGCTTCTTTTTCGTTTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGAGCAAAGCAATATCCGGGGGCGTCACATGCTTACA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCCGCTTTCGGAGCTACCGGACGAACCGGCGGGATTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCGAAACTGTATAGGAGAGAAGTGCGGGTGTTTCGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCCGGGAAAGAAACGAAGTAATTACTCCCCTTACC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAGGAAGCTACCGTTTCGTGTCGTATTATGATTTATTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCATGCCCCGGTAAGTATTATCCGCTGCAGGAGAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAAAAGGGAGGAATGCGAAATGAGGAAGAACGTCGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GACAAGCACACATTCTTTGCTGTTCTTGAAGAGATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AACCAGATTTGGAAGAGGGTGTTGTCCTATCAAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCCCCGGCCGGCCGGTGCCTGCCGCAAGGATGACG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGGAACGACGCAGGCCCGTACTGGCGGATTTCGTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGGAGAATTTTCCTTTGTTTCCCTTGCCCCTGTTCT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGGACTACCAAATTTAAATAAGCCATTGCGAGAGAGCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAGAAAGCTCTTGCTACGTTGCATGGAGGCGTTTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTCACTGCGGCGCGATCCGGCGTTATGAGCGGAGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTTCCTAATGAACCATCCCAATAAACTCACCGTCAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAGAGTTTGCTGCTGATATATCGATTGATCTTCAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCCGGACAATACCCTCATGATACCGTCCTCGGTTCTTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018870.1\|WP_015051476.1\|2464856_2465594_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NC_018870.1\|WP_015051469.1\|2438070_2438394_+\|transposase	unknown	unknown	gnl\|CDD\|366690
NC_018870.1\|WP_015049782.1\|2453138_2453459_-\|IS66-family-insertion-sequence-hypothetical-protein	unknown	unknown	gnl\|CDD\|225511
NC_018870.1\|WP_037999167.1\|2466877_2467384_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_018870.1\|WP_081578676.1\|2458292_2459963_+\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_018870.1\|WP_037999166.1\|2470356_2471271_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_018870.1\|WP_015051471.1\|2440644_2441883_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376773
NC_018870.1\|WP_148275911.1\|2436557_2436800_+\|hypothetical-protein	unknown	unknown	unknown
NC_018870.1\|WP_015051472.1\|2448405_2449620_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018870.1\|WP_015051480.1\|2467373_2469641_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_018870.1\|WP_081578676.1\|2446079_2447750_-\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_018870.1\|WP_015051478.1\|2465873_2466866_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_018870.1\|WP_015051477.1\|2465607_2465871_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_018870.1\|WP_015051468.1\|2437832_2438030_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275209
NC_018870.1\|WP_148276019.1\|2469627_2470320_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_018870.1\|WP_015051475.1\|2452788_2453145_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NC_018870.1\|WP_015051470.1\|2438417_2439062_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|379098
NC_018870.1\|WP_148276018.1\|2437231_2437552_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372110
NC_018870.1\|WP_015051472.1\|2442275_2443490_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018870.1\|WP_037999814.1\|2436950_2437226_+\|BrnT-family-toxin	unknown	unknown	gnl\|CDD\|225481

Protein	Function_ID	Function_description	E-value
NC_018870.1\|WP_015051470.1\|2438417_2439062_+\|IS3-family-transposase	gnl\|CDD\|379098	pfam13276, HTH_21, HTH-like domain. This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.	7.64926e-08
NC_018870.1\|WP_015051476.1\|2464856_2465594_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.60943e-42
NC_018870.1\|WP_015051469.1\|2438070_2438394_+\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	1.36302e-09
NC_018870.1\|WP_015051478.1\|2465873_2466866_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	8.78104e-171
NC_018870.1\|WP_081578676.1\|2458292_2459963_+\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.8014e-28
NC_018870.1\|WP_037999166.1\|2470356_2471271_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	8.44442e-77
NC_018870.1\|WP_015051471.1\|2440644_2441883_-\|IS110-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	5.273e-26
NC_018870.1\|WP_037999167.1\|2466877_2467384_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.89318e-70
NC_018870.1\|WP_015051472.1\|2448405_2449620_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.31767e-41
NC_018870.1\|WP_015051480.1\|2467373_2469641_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	3.72763e-54
NC_018870.1\|WP_081578676.1\|2446079_2447750_-\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.8014e-28
NC_018870.1\|WP_015051477.1\|2465607_2465871_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.43479e-28
NC_018870.1\|WP_015051468.1\|2437832_2438030_+\|hypothetical-protein	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	4.96046e-15
NC_018870.1\|WP_148276019.1\|2469627_2470320_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	4.95478e-37
NC_018870.1\|WP_015051475.1\|2452788_2453145_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	1.30076e-55
NC_018870.1\|WP_015049782.1\|2453138_2453459_-\|IS66-family-insertion-sequence-hypothetical-protein	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.000769281
NC_018870.1\|WP_148276018.1\|2437231_2437552_+\|hypothetical-protein	gnl\|CDD\|372110	pfam12441, CopG_antitoxin, CopG antitoxin of type II toxin-antitoxin system. CopG antitoxin is a member of a type II toxin-antitoxin system family found in bacteria and archaea. Most antitoxins encoded by the relBE and parDE loci belong to the MetJ/Arc/CopG family of dimeric proteins which bind DNA through N-terminal ribbon-helix-helix (RHH) motifs. The toxin for CopG proteins falls into the family BrnT_toxin, pfam04365.	8.50953e-11
NC_018870.1\|WP_015051472.1\|2442275_2443490_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.31767e-41
NC_018870.1\|WP_037999814.1\|2436950_2437226_+\|BrnT-family-toxin	gnl\|CDD\|225481	COG2929, COG2929, Uncharacterized protein conserved in bacteria [Function unknown].	3.61785e-09

>NC_018870.1|WP_015051472.1|2448405_2449620_+|IS110-family-transposase
MDVVFPYCCGLDVHKNSVVACVITPDEKEIRTFGTMTRDLLNLADWLTSKGCTHVAMESTGVYWKPIYNILEQYQLELLVVNAKHIKAVPGRKTDVKDAEWIADLLRHGLLKGSYIPDREQRELRELVGYRKSLVEERAREVNRIQKTLEGAGIKLSSVATDVVGVSGRAMIEGIISGIDDPAVLADFAQKKLKKKKEQLEQALFGLVGKHQRLLLAAQLRHIDYLDQEIARLDQQIEERMRPFEAELALLDTIPGVGRRTSQVILACIGADMSRFPSAAHLSSWAGVAPGNNESAGKRKSGKTTKGNTLLHTTLIQAARAASRTKNTYLSALYHRVAARRGANRAAVAVAHSILVSVYYMLIRRVPYHDLGGDYFEKRNSKAVVNRAVKQLEQLGYRVSIEVA
>NC_018870.1|WP_081578676.1|2446079_2447750_-|IS1634-family-transposase
MWYNVDMYIRTIQRKNKDGSVVRYIQLAHNQWDPQARCAKAKVLFNFGREEEVDREALKRLVKSINRFLGPGETLRYEAETGAAPLKFITSRPLGGAWVLDRLWEELGIKGVLETLLKKRQYKTPVERAIFAMAANRALDPMSKRGVEEWVKEDAVIPGVEEIPLQQLYRAMDFLLENEAELQKQVYYSVANLLNLEVDILYFDTTSTYFEIEDEDEDGGLRRRGHSKDHRPDLPQAVIGLAVTRDGIPVRCWVWPGNTADISVVEQVKKDLIGWKLGRVITVLDRGFNSEDNLRCLQRAGGHYIAGEKLRSGKENTVQALKRGGRYQTVRDNLEVKEIVVGNGEARERYILVRNPEEAARDKARREKIIKELEEQLPHIKTHAKAVCELMAHPVYGRYLKLDSRSLPKIDRAKIREEEKLDGKYLLRTSDDTLSAEDVALGYKQLLLVEDAFRTLKSRLELRPVYHRLEDRIRSHVLLCWLALLLIRIAENRTGQTWCSLRATLQRMQLGEFSGTAGQVRQRTETTPAQKQIFKALAVKEPPLLFSINPTAKKNA
>NC_018870.1|WP_015051472.1|2442275_2443490_+|IS110-family-transposase
MDVVFPYCCGLDVHKNSVVACVITPDEKEIRTFGTMTRDLLNLADWLTSKGCTHVAMESTGVYWKPIYNILEQYQLELLVVNAKHIKAVPGRKTDVKDAEWIADLLRHGLLKGSYIPDREQRELRELVGYRKSLVEERAREVNRIQKTLEGAGIKLSSVATDVVGVSGRAMIEGIISGIDDPAVLADFAQKKLKKKKEQLEQALFGLVGKHQRLLLAAQLRHIDYLDQEIARLDQQIEERMRPFEAELALLDTIPGVGRRTSQVILACIGADMSRFPSAAHLSSWAGVAPGNNESAGKRKSGKTTKGNTLLHTTLIQAARAASRTKNTYLSALYHRVAARRGANRAAVAVAHSILVSVYYMLIRRVPYHDLGGDYFEKRNSKAVVNRAVKQLEQLGYRVSIEVA
>NC_018870.1|WP_015051471.1|2440644_2441883_-|IS110-family-transposase
MKLFVGIDVSMKDFKARMFDAEGEEIAKRMRYKNDDPGAESFVKYLVEICGANEVDSLRIGMESTSVYGWHLQMRLAGEPLLASFHPQVYVFNPKVIANFRKQYVDIPKDDWFDCLVIADRLRFGRLPESCQVDFRYLPLQRLTRFRYHLIQTITREKNYFLTNLFLKFNTICQDKVLSDIFGATSEAILTEFLSPEEIAARPLDELIDFLMEKGKSHFSNPEATAKALKHAAACAYRLHGSLLEPVNLILATSLQTICTLEQQVKSIDRAIEKELSHFPNTLQSMPGMGPVCTAGIIAEIGDIHRFDNEKAVAKFAGLTWRKHQSGEFEADDTPLTKTGNVYLRYYFVMAADSVRKWDPRFAEFYARKFKESSTHHHRRALVLTARKLVRVVDALLRSNQLYVPQGQRKVV
>NC_018870.1|WP_015051470.1|2438417_2439062_+|IS3-family-transposase
MGYKVSLVLRIIGISRSTYYPNLKRQPKPRIFAGGRPKSHYTFTSDNKVVSNEQVKEWLCELITAEGFAYGYLKLTHCLRRKFHLIINKKKVYRLCKELDILRPQRKIKRKHPRRLARNRVITASNQLWEADLKYGYIAGEDRFFFIMPIIDVFDRCIVAYHIGLSCEAKDARVMSLPAMPKRMQRLSTSSTFTTKPGFIQQLNTYHRWNAINC
>NC_018870.1|WP_015051469.1|2438070_2438394_+|transposase
MNRKQYSPEMKMQIVKETLETGNASIVARRHDIAPSLVARWARCYKRYGTFYPQKEVPGTNGSCIPPDYKKITKENEQLKKLLGEKDLEIAILRDLLKKTNLPFPIK
>NC_018870.1|WP_015051468.1|2437832_2438030_+|hypothetical-protein
MEKVLERSNMLRALRRVKSNKGADGVDGMEIKSLRPYLKEHWPKIKEELLKGTYKLFSPLTRLNS
>NC_018870.1|WP_148276018.1|2437231_2437552_+|hypothetical-protein
MAKKKELPEFKGDEIPEFASEEEAAEFFDRHSFAEAMERGVLAPDDPAEPDPELAATSKTKRVTLRLRVSQIEAAKEIAKRKDIPYQTLLRSWIAEGIRREMEGKG
>NC_018870.1|WP_037999814.1|2436950_2437226_+|BrnT-family-toxin
MAKAKRFEWDSRNVNHIARHNVKPEEVEEVFLSRPLIRKARSGLKVAMGRTDAGHYLFVVFALKSSDVIRVITARDMSTSERRYYRRERGE
>NC_018870.1|WP_148275911.1|2436557_2436800_+|hypothetical-protein
MSDVVEKPTGGSFPSDLKLGTTTWCPYCGGVKGFVWDTDAFTSRYPNCGVSTEDSYVCVCSSGPVKGGRASTRVSASTPP
>NC_018870.1|WP_015051475.1|2452788_2453145_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MLNEAGIDRVYLACGATDLRKSIDGLAVLVKEGFELDPFSSCLFVFCNRKRDKLKILHWEHNGFWLYYRRLEKGKFIWPQDTTSSTITISRRELRWLLDGLPLKQPKAHPEVKARTIL
>NC_018870.1|WP_015049782.1|2453138_2453459_-|IS66-family-insertion-sequence-hypothetical-protein
MTRAELQKLWEARIAEYRESGQSVKEWCASHEGINPRQLWYWLRKFKNQTPAPPEISNRWLSVEISEEDSLEQALLVKIGPASIEVRPGFDPALLTKVVQVLMALC
>NC_018870.1|WP_081578676.1|2458292_2459963_+|IS1634-family-transposase
MWYNVDMYIRTIQRKNKDGSVVRYIQLAHNQWDPQARCAKAKVLFNFGREEEVDREALKRLVKSINRFLGPGETLRYEAETGAAPLKFITSRPLGGAWVLDRLWEELGIKGVLETLLKKRQYKTPVERAIFAMAANRALDPMSKRGVEEWVKEDAVIPGVEEIPLQQLYRAMDFLLENEAELQKQVYYSVANLLNLEVDILYFDTTSTYFEIEDEDEDGGLRRRGHSKDHRPDLPQAVIGLAVTRDGIPVRCWVWPGNTADISVVEQVKKDLIGWKLGRVITVLDRGFNSEDNLRCLQRAGGHYIAGEKLRSGKENTVQALKRGGRYQTVRDNLEVKEIVVGNGEARERYILVRNPEEAARDKARREKIIKELEEQLPHIKTHAKAVCELMAHPVYGRYLKLDSRSLPKIDRAKIREEEKLDGKYLLRTSDDTLSAEDVALGYKQLLLVEDAFRTLKSRLELRPVYHRLEDRIRSHVLLCWLALLLIRIAENRTGQTWCSLRATLQRMQLGEFSGTAGQVRQRTETTPAQKQIFKALAVKEPPLLFSINPTAKKNA
>NC_018870.1|WP_015051476.1|2464856_2465594_-|CRISPR-associated-endoribonuclease-Cas6
MRLIVEFRATENERITLPLQYNKAVQGMIYQRVREHLPELHDRGFVSAGRVFRLFVFSRIEGSGVKIINGMISFNSPVRIKIGSPNNNFLECLANSLLRTPQIDIGGSPLVVESVAIARNPDFSSGRVKVRAISPITVYSTLMSADGRKKTYYYHPEEKEFSDQIRNNIIKKGALLGVDDKEAYFTIEPYRVRNTDLKTVYYKDYVVKGWLGQYLLRGTPELLNIAYDAGIGAKNSQGFGMVEII
>NC_018870.1|WP_015051477.1|2465607_2465871_-|CRISPR-associated-endonuclease-Cas2
MFVIEVYDVNEKRVAKVLKVSRKYLYWVQNSVLEGEISEANFRRLKEELLEIIDLKEDSLIFYTFRTTKYSERQCFGVLKGGEETIF
>NC_018870.1|WP_015051478.1|2465873_2466866_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MRKSIYLLNSGELRRENNTICLITDEGKRFLPVEDIGEIHVFGEVDLNKRLLEFLSEKEIILHYYNHYDYYMGSFYPREHFNSGYMTVKQAEHYINPELRICLARAFVTGAVKNIRQVLMYYRNRGKEVGSAFERIEKLMGEIDSASSVDELMAYEGNIRDAYYGTFDLIIDNPDYVFEVRSKRPPKNRLNALISFGNTLLYTTTLSEIYRTHLDPRIGYLHTSNFRRFSLNLDVAEIFKPILVDRLIFYLTGKQMLKKSHFEKKLDGVVLSRSGRTLFIQNFEQRMMSTIKHRELGRQVSYRRLIRMELYKLEKHLMGEADYQPFVARW
>NC_018870.1|WP_037999167.1|2466877_2467384_-|CRISPR-associated-protein-Cas4
MIGEHWPVNGTLVWYYTICHRQVWLMARQLTPDEDDDNVAIGRFIHEHSYRRDRHELAVGNIRIDLMQASRDEVLIAEIKKSSRFLESARLQLKYYLFVLKSLGLDFKGVLLVPEERKRELVTLEEEDLVEIERIIGEIRRIIDSPVPPPAVRTRWCRPCAYAEFCWA
>NC_018870.1|WP_015051480.1|2467373_2469641_-|CRISPR-associated-helicase/endonuclease-Cas3
MSPGEVYSHKGKRLEQHLLETAELAQKIARHFRLELEEGERWALLLHDLAKAHPLFQKHLLQQKGRFGHAAPSAALVLGLTGDLLCTEAVRRHHSSLENLDEAKKFWFCWDYQENACGVIGKIPVWNGAEAVMEALGHQLAKWGELLPAQADWDELIFERVEFFPPDEEKMEEAWLRLRMLYSLLVTADRYNAAVGREMEYHPLRIDQKRVEDFAASLRGRPLAEWRQQVREEVVRKAEEVLKKPGIYTLTLPTGAGKTLVGLELAMLAAERFAATGIIYVLPFISLVEQNADVARVLFKDASPVREDHYLSEVAGEEGDPENSSPQERFLSFFRYWQEPVVITTMAKFWEVLYSPKGNDTMSLHRLSRAVVILDEPQAIPSCYWQGFGKTLNLLSEKLNTTFILMTATQPEIAQGLELAPRPYFFPMIRHRFEWRRERLTVPELLGSPDVISKLLAKSALLVFNTHRSALLAYLELQSRGVTSYFLSGWVTPLDRRATLQQIREDESAGKPARLVSTQVVEAGVDLDFQFVYRDLGPLDSIIQVAGRCNRHGKREQGEVLVCELCDENGRSYAGYVYDSTLLVATKAVLKDSFDERDCPGMVAAYYRKVREITAENPLWEDISSGRWGEFHDLIEKEERGEATLVVAYEGVENDLDLLSRQAAPDEDVMRMVEQKREASRRLGLHAVSVPVKMLEEWLLRVGGMIYGAESGDILRKVSSGIYLVQGEGIGRIYSRRTGFMPPDLEAAGDGVDDW
>NC_018870.1|WP_148276019.1|2469627_2470320_-|type-I-B-CRISPR-associated-protein-Cas5
MAMFRKPYTTTSMVSFPFPPPTAVCGLIAAIVGLDHGASEGALKAEYWDRVRGMQVALGLRRPVAWFSTAVNLIKFKSPSGDMGEHIQVKHQLLKRPAYRIYVRGGEVYDELKKRLERQEFIFTPYLGVAFALAEYSYVGEFRETPVEEEAMGIDSVLPLYGDVRLDLQQSGCLHSEVVPFRLDGIRRQQETVNVIYPEYRVNSRIYLRNRGDVEVSLVGTERVAWFEPW
>NC_018870.1|WP_037999166.1|2470356_2471271_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MEFKRRREFVFLYTVVDANPNGDPLNENHPRYDEDTLQALVSDVRIKRTVRDEWVNQERLVFVDGKPKTLKTRFEELKQSTGKEKGDEVLRECIDTRLFGVTFALGNESFAWTGPVQFKWGRSLHACTFEFIQGTSAFATEGGEGKEKQQRSFRNEYKVPFALIATYGIANQHAAKYTGATEEDLDLLAEALWSGTDNLITRSKQEHKSRFYLEITYKEGFNGKIGALDEKLRLLTAEGEEPDRDAQRALRRLSQLVVDIEPLIDAVEEKSDQIDRVRAIVNKELSLLGIDRLKNLAGAVIEVR

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Crispr_ID: NC_018870_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018870_9

2453564-2455403

TypeI-B

Consensus_repeat	Method
GTTTCAATTCCTCATAGGTACGCTGAAAAC	PILER-CR
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CRISPRCasFinder
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CRT

27 spacers

cas6,cas2,cas1,cas4,cas3,cas5,cas7,cas8b1

The CRISPR arrays of NC_018870_9

>merge|NC_018870|9|2453564-2455403|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATTCCTCATAGGTACGCTGAAAACTTTGACCACCACCTCATCCTTAGCAAATGCTAACGGAGTTTCAATTCCTCATAGGTACGCTGAAAACGCTCTTCAAGCGGAATCCCATCATCATTCACAACATGTTTCAATTCCTCATAGGTACGCTGAAAACGATGCATCTGAAGCACTTAAATACGCGGAGAAGCTCAAGTTTCAATTCCTCATAGGTACGCTGAAAACGGAGCCTGCCGGCGGAGTAAAATAGGCTTGCCCGAGTTTCAATTCCTCATAGGTACGCTGAAAACAATGAAAGGAGGAGGAAGTAAGGTGTTCATGGTCGTGTTTCAATTCCTCATAGGTACGCTGAAAACTCCTCCTCCTTTCATTCAAATTCCAGCGTAATCCTGGTTTCAATTCCTCATAGGTACGCTGAAAACTCAAAGTACATCACGAAGGAGTTAGGTCTATATATACCAGTTTCAATTCCTCATAGGTACGCTGAAAACCGACAAGCACACATTCTTTGCTGTTCTTGAAGAGATGGTTTCAATTCCTCATAGGTACGCTGAAAACTTCATCAGCACTCCTTTCATTTCTTTTTCGGATGTCGTTTCAATTCCTCATAGGTACGCTGAAAACGTTAACCAAGGAAATGCAGTAGCTGAGCAGTCTCCAGTTTCAATTCCTCATAGGTACGCTGAAAACAGTTGAAGGCGATGCGCGGTCGGATGTGGAGCTTTAGTTTCAATTCCTCATAGGTACGCTGAAAACAAAGGAGATTGATGACCTCTACCTTGAGAATCCTGCGTTTCAATTCCTCATAGGTACGCTGAAAACGGAATCCTTTACGGATGGGGCTGCGGTGATTACGGAGTTTCAATTCCTCATAGGTACGCTGAAAACCAGTTTCGCCGGGATAAATATTCGCCGCCCATGCCGGTTTCAATTCCTCATAGGTACGCTGAAAACACCAGTGCGTCCAACTCTCTGCCGGCTTCCAGTTTGTGTTTCAATTCCTCATAGGTACGCTGAAAACCGTTGTAAGGTTTAACGAGTTCTTTACGTTTTTCTTCGTTTCAATTCCTCATAGGTACGCTGAAAACTCAGTACCATCTGCATTATATGTCGTAAAAGTATAAGTTTCAATTCCTCATAGGTACGCTGAAAACGGAAGAGATGCAATCCCTCCCGAAAGTGTAAGCTGAGTTTCAATTCCTCATAGGTACGCTGAAAACTCAGAAAACTACCATCTGACCACCAGACAGGTCTTACACTAGGTTTCAATTCCTCATAGGTACGCTGAAAACCAGCAACTGACATTTCAAGACCTCCTTAAACTTAATTGTTTCAATTCCTCATAGGTACGCTGAAAACAATGATTACGGGAACAGATTCCTCGGTGGTTACTATGGTTTCAATTCCTCATAGGTACGCTGAAAACTGGCGTATCGTGCCGCCGTGCCCCGAGAATCGCTCACGCGTTTCAATTCCTCATAGGTACGCTGAAAACGAAAGGAGTGCTGATGAATCGTGACTGCTCGTGAGTTCTGTTTCAATTCCTCATAGGTACGCTGAAAACTTATGCGTCCCGATGCTGAGTATGAAGTTATCGAAGTAGTTTCAATTCCTCATAGGTACGCTGAAAACCCGGGCCGGTAAAGCGGATTCTCCTGGATCTGGTGGGGTGTTTCAATTCCTCATAGGTACGCTGAAAACTTCTCCCTCCTGCTTTTATGAGTTTTTTAGCGTTTCGTTTCAATTCCTCATAGGTACGCTGAAAACACATTTTCAATTTTATGTAGATTGAAATATCGTTCTGGTTTCAATTCCTCATAGACCACCATGCCGC

>NC_018870|9|9|2453564-2455201|PILER-CR
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTTGACCACCACCTCATCCTTAGCAAATGCTAACGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCTCTTCAAGCGGAATCCCATCATCATTCACAACAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GATGCATCTGAAGCACTTAAATACGCGGAGAAGCTCAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAGCCTGCCGGCGGAGTAAAATAGGCTTGCCCGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AATGAAAGGAGGAGGAAGTAAGGTGTTCATGGTCGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCCTCCTCCTTTCATTCAAATTCCAGCGTAATCCTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCAAAGTACATCACGAAGGAGTTAGGTCTATATATACCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGACAAGCACACATTCTTTGCTGTTCTTGAAGAGATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTCATCAGCACTCCTTTCATTTCTTTTTCGGATGTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTTAACCAAGGAAATGCAGTAGCTGAGCAGTCTCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGTTGAAGGCGATGCGCGGTCGGATGTGGAGCTTTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAAGGAGATTGATGACCTCTACCTTGAGAATCCTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAATCCTTTACGGATGGGGCTGCGGTGATTACGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAGTTTCGCCGGGATAAATATTCGCCGCCCATGCCG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACCAGTGCGTCCAACTCTCTGCCGGCTTCCAGTTTGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGTTGTAAGGTTTAACGAGTTCTTTACGTTTTTCTTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCAGTACCATCTGCATTATATGTCGTAAAAGTATAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAAGAGATGCAATCCCTCCCGAAAGTGTAAGCTGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCAGAAAACTACCATCTGACCACCAGACAGGTCTTACACTAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAGCAACTGACATTTCAAGACCTCCTTAAACTTAATT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AATGATTACGGGAACAGATTCCTCGGTGGTTACTATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGGCGTATCGTGCCGCCGTGCCCCGAGAATCGCTCACGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAAAGGAGTGCTGATGAATCGTGACTGCTCGTGAGTTCT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTATGCGTCCCGATGCTGAGTATGAAGTTATCGAAGTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC

>NC_018870|9|8|2453564-2455337|CRISPRCasFinder
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTTGACCACCACCTCATCCTTAGCAAATGCTAACGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCTCTTCAAGCGGAATCCCATCATCATTCACAACAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GATGCATCTGAAGCACTTAAATACGCGGAGAAGCTCAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAGCCTGCCGGCGGAGTAAAATAGGCTTGCCCGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AATGAAAGGAGGAGGAAGTAAGGTGTTCATGGTCGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCCTCCTCCTTTCATTCAAATTCCAGCGTAATCCTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCAAAGTACATCACGAAGGAGTTAGGTCTATATATACCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGACAAGCACACATTCTTTGCTGTTCTTGAAGAGATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTCATCAGCACTCCTTTCATTTCTTTTTCGGATGTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTTAACCAAGGAAATGCAGTAGCTGAGCAGTCTCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGTTGAAGGCGATGCGCGGTCGGATGTGGAGCTTTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAAGGAGATTGATGACCTCTACCTTGAGAATCCTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAATCCTTTACGGATGGGGCTGCGGTGATTACGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAGTTTCGCCGGGATAAATATTCGCCGCCCATGCCG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACCAGTGCGTCCAACTCTCTGCCGGCTTCCAGTTTGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGTTGTAAGGTTTAACGAGTTCTTTACGTTTTTCTTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCAGTACCATCTGCATTATATGTCGTAAAAGTATAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAAGAGATGCAATCCCTCCCGAAAGTGTAAGCTGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCAGAAAACTACCATCTGACCACCAGACAGGTCTTACACTAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAGCAACTGACATTTCAAGACCTCCTTAAACTTAATT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AATGATTACGGGAACAGATTCCTCGGTGGTTACTATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGGCGTATCGTGCCGCCGTGCCCCGAGAATCGCTCACGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAAAGGAGTGCTGATGAATCGTGACTGCTCGTGAGTTCT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTATGCGTCCCGATGCTGAGTATGAAGTTATCGAAGTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCGGGCCGGTAAAGCGGATTCTCCTGGATCTGGTGGGGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTCTCCCTCCTGCTTTTATGAGTTTTTTAGCGTTTC
GTTTCAATTCCTCATAGGTACGCTGAAAACA

>NC_018870|9|8|2453564-2455403|CRT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTTGACCACCACCTCATCCTTAGCAAATGCTAACGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCTCTTCAAGCGGAATCCCATCATCATTCACAACAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GATGCATCTGAAGCACTTAAATACGCGGAGAAGCTCAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAGCCTGCCGGCGGAGTAAAATAGGCTTGCCCGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AATGAAAGGAGGAGGAAGTAAGGTGTTCATGGTCGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCCTCCTCCTTTCATTCAAATTCCAGCGTAATCCTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCAAAGTACATCACGAAGGAGTTAGGTCTATATATACCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGACAAGCACACATTCTTTGCTGTTCTTGAAGAGATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTCATCAGCACTCCTTTCATTTCTTTTTCGGATGTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTTAACCAAGGAAATGCAGTAGCTGAGCAGTCTCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGTTGAAGGCGATGCGCGGTCGGATGTGGAGCTTTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAAGGAGATTGATGACCTCTACCTTGAGAATCCTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAATCCTTTACGGATGGGGCTGCGGTGATTACGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAGTTTCGCCGGGATAAATATTCGCCGCCCATGCCG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACCAGTGCGTCCAACTCTCTGCCGGCTTCCAGTTTGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGTTGTAAGGTTTAACGAGTTCTTTACGTTTTTCTTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCAGTACCATCTGCATTATATGTCGTAAAAGTATAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAAGAGATGCAATCCCTCCCGAAAGTGTAAGCTGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCAGAAAACTACCATCTGACCACCAGACAGGTCTTACACTAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAGCAACTGACATTTCAAGACCTCCTTAAACTTAATT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AATGATTACGGGAACAGATTCCTCGGTGGTTACTATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGGCGTATCGTGCCGCCGTGCCCCGAGAATCGCTCACGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAAAGGAGTGCTGATGAATCGTGACTGCTCGTGAGTTCT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTATGCGTCCCGATGCTGAGTATGAAGTTATCGAAGTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCGGGCCGGTAAAGCGGATTCTCCTGGATCTGGTGGGGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTCTCCCTCCTGCTTTTATGAGTTTTTTAGCGTTTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACATTTTCAATTTTATGTAGATTGAAATATCGTTCTG
GTTTCAATTCCTCATAGACCACCATGCCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018870.1\|WP_015051476.1\|2464856_2465594_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NC_018870.1\|WP_015051469.1\|2438070_2438394_+\|transposase	unknown	unknown	gnl\|CDD\|366690
NC_018870.1\|WP_015051478.1\|2465873_2466866_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_018870.1\|WP_015051484.1\|2471695_2473132_-\|CRISPR-associated-protein	cas8b1	pfam09484_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_018870.1\|WP_081578676.1\|2458292_2459963_+\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_018870.1\|WP_037999166.1\|2470356_2471271_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_018870.1\|WP_015051471.1\|2440644_2441883_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376773
NC_018870.1\|WP_037999167.1\|2466877_2467384_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_018870.1\|WP_015051472.1\|2448405_2449620_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018870.1\|WP_015051480.1\|2467373_2469641_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_018870.1\|WP_081578676.1\|2446079_2447750_-\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_018870.1\|WP_015051483.1\|2471273_2471699_-\|CRISPR-associated-protein	cas8b1	mkCas0119_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_018870.1\|WP_015051477.1\|2465607_2465871_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_018870.1\|WP_015051468.1\|2437832_2438030_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275209
NC_018870.1\|WP_148276019.1\|2469627_2470320_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_018870.1\|WP_015051475.1\|2452788_2453145_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NC_018870.1\|WP_015049782.1\|2453138_2453459_-\|IS66-family-insertion-sequence-hypothetical-protein	unknown	unknown	gnl\|CDD\|225511
NC_018870.1\|WP_148276018.1\|2437231_2437552_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372110
NC_018870.1\|WP_015051472.1\|2442275_2443490_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018870.1\|WP_015051470.1\|2438417_2439062_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|379098

Protein	Function_ID	Function_description	E-value
NC_018870.1\|WP_015051476.1\|2464856_2465594_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.60943e-42
NC_018870.1\|WP_015051469.1\|2438070_2438394_+\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	1.36302e-09
NC_018870.1\|WP_015051478.1\|2465873_2466866_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	8.78104e-171
NC_018870.1\|WP_015051484.1\|2471695_2473132_-\|CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.3023e-20
NC_018870.1\|WP_081578676.1\|2458292_2459963_+\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.8014e-28
NC_018870.1\|WP_037999166.1\|2470356_2471271_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	8.44442e-77
NC_018870.1\|WP_015051471.1\|2440644_2441883_-\|IS110-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	5.273e-26
NC_018870.1\|WP_037999167.1\|2466877_2467384_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.89318e-70
NC_018870.1\|WP_015051472.1\|2448405_2449620_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.31767e-41
NC_018870.1\|WP_015051480.1\|2467373_2469641_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	3.72763e-54
NC_018870.1\|WP_081578676.1\|2446079_2447750_-\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.8014e-28
NC_018870.1\|WP_015051483.1\|2471273_2471699_-\|CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	7.70598e-09
NC_018870.1\|WP_015051477.1\|2465607_2465871_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.43479e-28
NC_018870.1\|WP_015051468.1\|2437832_2438030_+\|hypothetical-protein	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	4.96046e-15
NC_018870.1\|WP_148276019.1\|2469627_2470320_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	4.95478e-37
NC_018870.1\|WP_015051475.1\|2452788_2453145_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	1.30076e-55
NC_018870.1\|WP_015049782.1\|2453138_2453459_-\|IS66-family-insertion-sequence-hypothetical-protein	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.000769281
NC_018870.1\|WP_148276018.1\|2437231_2437552_+\|hypothetical-protein	gnl\|CDD\|372110	pfam12441, CopG_antitoxin, CopG antitoxin of type II toxin-antitoxin system. CopG antitoxin is a member of a type II toxin-antitoxin system family found in bacteria and archaea. Most antitoxins encoded by the relBE and parDE loci belong to the MetJ/Arc/CopG family of dimeric proteins which bind DNA through N-terminal ribbon-helix-helix (RHH) motifs. The toxin for CopG proteins falls into the family BrnT_toxin, pfam04365.	8.50953e-11
NC_018870.1\|WP_015051472.1\|2442275_2443490_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.31767e-41
NC_018870.1\|WP_015051470.1\|2438417_2439062_+\|IS3-family-transposase	gnl\|CDD\|379098	pfam13276, HTH_21, HTH-like domain. This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.	7.64926e-08

>NC_018870.1|WP_015049782.1|2453138_2453459_-|IS66-family-insertion-sequence-hypothetical-protein
MTRAELQKLWEARIAEYRESGQSVKEWCASHEGINPRQLWYWLRKFKNQTPAPPEISNRWLSVEISEEDSLEQALLVKIGPASIEVRPGFDPALLTKVVQVLMALC
>NC_018870.1|WP_015051475.1|2452788_2453145_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MLNEAGIDRVYLACGATDLRKSIDGLAVLVKEGFELDPFSSCLFVFCNRKRDKLKILHWEHNGFWLYYRRLEKGKFIWPQDTTSSTITISRRELRWLLDGLPLKQPKAHPEVKARTIL
>NC_018870.1|WP_015051472.1|2448405_2449620_+|IS110-family-transposase
MDVVFPYCCGLDVHKNSVVACVITPDEKEIRTFGTMTRDLLNLADWLTSKGCTHVAMESTGVYWKPIYNILEQYQLELLVVNAKHIKAVPGRKTDVKDAEWIADLLRHGLLKGSYIPDREQRELRELVGYRKSLVEERAREVNRIQKTLEGAGIKLSSVATDVVGVSGRAMIEGIISGIDDPAVLADFAQKKLKKKKEQLEQALFGLVGKHQRLLLAAQLRHIDYLDQEIARLDQQIEERMRPFEAELALLDTIPGVGRRTSQVILACIGADMSRFPSAAHLSSWAGVAPGNNESAGKRKSGKTTKGNTLLHTTLIQAARAASRTKNTYLSALYHRVAARRGANRAAVAVAHSILVSVYYMLIRRVPYHDLGGDYFEKRNSKAVVNRAVKQLEQLGYRVSIEVA
>NC_018870.1|WP_081578676.1|2446079_2447750_-|IS1634-family-transposase
MWYNVDMYIRTIQRKNKDGSVVRYIQLAHNQWDPQARCAKAKVLFNFGREEEVDREALKRLVKSINRFLGPGETLRYEAETGAAPLKFITSRPLGGAWVLDRLWEELGIKGVLETLLKKRQYKTPVERAIFAMAANRALDPMSKRGVEEWVKEDAVIPGVEEIPLQQLYRAMDFLLENEAELQKQVYYSVANLLNLEVDILYFDTTSTYFEIEDEDEDGGLRRRGHSKDHRPDLPQAVIGLAVTRDGIPVRCWVWPGNTADISVVEQVKKDLIGWKLGRVITVLDRGFNSEDNLRCLQRAGGHYIAGEKLRSGKENTVQALKRGGRYQTVRDNLEVKEIVVGNGEARERYILVRNPEEAARDKARREKIIKELEEQLPHIKTHAKAVCELMAHPVYGRYLKLDSRSLPKIDRAKIREEEKLDGKYLLRTSDDTLSAEDVALGYKQLLLVEDAFRTLKSRLELRPVYHRLEDRIRSHVLLCWLALLLIRIAENRTGQTWCSLRATLQRMQLGEFSGTAGQVRQRTETTPAQKQIFKALAVKEPPLLFSINPTAKKNA
>NC_018870.1|WP_015051472.1|2442275_2443490_+|IS110-family-transposase
MDVVFPYCCGLDVHKNSVVACVITPDEKEIRTFGTMTRDLLNLADWLTSKGCTHVAMESTGVYWKPIYNILEQYQLELLVVNAKHIKAVPGRKTDVKDAEWIADLLRHGLLKGSYIPDREQRELRELVGYRKSLVEERAREVNRIQKTLEGAGIKLSSVATDVVGVSGRAMIEGIISGIDDPAVLADFAQKKLKKKKEQLEQALFGLVGKHQRLLLAAQLRHIDYLDQEIARLDQQIEERMRPFEAELALLDTIPGVGRRTSQVILACIGADMSRFPSAAHLSSWAGVAPGNNESAGKRKSGKTTKGNTLLHTTLIQAARAASRTKNTYLSALYHRVAARRGANRAAVAVAHSILVSVYYMLIRRVPYHDLGGDYFEKRNSKAVVNRAVKQLEQLGYRVSIEVA
>NC_018870.1|WP_015051471.1|2440644_2441883_-|IS110-family-transposase
MKLFVGIDVSMKDFKARMFDAEGEEIAKRMRYKNDDPGAESFVKYLVEICGANEVDSLRIGMESTSVYGWHLQMRLAGEPLLASFHPQVYVFNPKVIANFRKQYVDIPKDDWFDCLVIADRLRFGRLPESCQVDFRYLPLQRLTRFRYHLIQTITREKNYFLTNLFLKFNTICQDKVLSDIFGATSEAILTEFLSPEEIAARPLDELIDFLMEKGKSHFSNPEATAKALKHAAACAYRLHGSLLEPVNLILATSLQTICTLEQQVKSIDRAIEKELSHFPNTLQSMPGMGPVCTAGIIAEIGDIHRFDNEKAVAKFAGLTWRKHQSGEFEADDTPLTKTGNVYLRYYFVMAADSVRKWDPRFAEFYARKFKESSTHHHRRALVLTARKLVRVVDALLRSNQLYVPQGQRKVV
>NC_018870.1|WP_015051470.1|2438417_2439062_+|IS3-family-transposase
MGYKVSLVLRIIGISRSTYYPNLKRQPKPRIFAGGRPKSHYTFTSDNKVVSNEQVKEWLCELITAEGFAYGYLKLTHCLRRKFHLIINKKKVYRLCKELDILRPQRKIKRKHPRRLARNRVITASNQLWEADLKYGYIAGEDRFFFIMPIIDVFDRCIVAYHIGLSCEAKDARVMSLPAMPKRMQRLSTSSTFTTKPGFIQQLNTYHRWNAINC
>NC_018870.1|WP_015051469.1|2438070_2438394_+|transposase
MNRKQYSPEMKMQIVKETLETGNASIVARRHDIAPSLVARWARCYKRYGTFYPQKEVPGTNGSCIPPDYKKITKENEQLKKLLGEKDLEIAILRDLLKKTNLPFPIK
>NC_018870.1|WP_015051468.1|2437832_2438030_+|hypothetical-protein
MEKVLERSNMLRALRRVKSNKGADGVDGMEIKSLRPYLKEHWPKIKEELLKGTYKLFSPLTRLNS
>NC_018870.1|WP_148276018.1|2437231_2437552_+|hypothetical-protein
MAKKKELPEFKGDEIPEFASEEEAAEFFDRHSFAEAMERGVLAPDDPAEPDPELAATSKTKRVTLRLRVSQIEAAKEIAKRKDIPYQTLLRSWIAEGIRREMEGKG
>NC_018870.1|WP_081578676.1|2458292_2459963_+|IS1634-family-transposase
MWYNVDMYIRTIQRKNKDGSVVRYIQLAHNQWDPQARCAKAKVLFNFGREEEVDREALKRLVKSINRFLGPGETLRYEAETGAAPLKFITSRPLGGAWVLDRLWEELGIKGVLETLLKKRQYKTPVERAIFAMAANRALDPMSKRGVEEWVKEDAVIPGVEEIPLQQLYRAMDFLLENEAELQKQVYYSVANLLNLEVDILYFDTTSTYFEIEDEDEDGGLRRRGHSKDHRPDLPQAVIGLAVTRDGIPVRCWVWPGNTADISVVEQVKKDLIGWKLGRVITVLDRGFNSEDNLRCLQRAGGHYIAGEKLRSGKENTVQALKRGGRYQTVRDNLEVKEIVVGNGEARERYILVRNPEEAARDKARREKIIKELEEQLPHIKTHAKAVCELMAHPVYGRYLKLDSRSLPKIDRAKIREEEKLDGKYLLRTSDDTLSAEDVALGYKQLLLVEDAFRTLKSRLELRPVYHRLEDRIRSHVLLCWLALLLIRIAENRTGQTWCSLRATLQRMQLGEFSGTAGQVRQRTETTPAQKQIFKALAVKEPPLLFSINPTAKKNA
>NC_018870.1|WP_015051476.1|2464856_2465594_-|CRISPR-associated-endoribonuclease-Cas6
MRLIVEFRATENERITLPLQYNKAVQGMIYQRVREHLPELHDRGFVSAGRVFRLFVFSRIEGSGVKIINGMISFNSPVRIKIGSPNNNFLECLANSLLRTPQIDIGGSPLVVESVAIARNPDFSSGRVKVRAISPITVYSTLMSADGRKKTYYYHPEEKEFSDQIRNNIIKKGALLGVDDKEAYFTIEPYRVRNTDLKTVYYKDYVVKGWLGQYLLRGTPELLNIAYDAGIGAKNSQGFGMVEII
>NC_018870.1|WP_015051477.1|2465607_2465871_-|CRISPR-associated-endonuclease-Cas2
MFVIEVYDVNEKRVAKVLKVSRKYLYWVQNSVLEGEISEANFRRLKEELLEIIDLKEDSLIFYTFRTTKYSERQCFGVLKGGEETIF
>NC_018870.1|WP_015051478.1|2465873_2466866_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MRKSIYLLNSGELRRENNTICLITDEGKRFLPVEDIGEIHVFGEVDLNKRLLEFLSEKEIILHYYNHYDYYMGSFYPREHFNSGYMTVKQAEHYINPELRICLARAFVTGAVKNIRQVLMYYRNRGKEVGSAFERIEKLMGEIDSASSVDELMAYEGNIRDAYYGTFDLIIDNPDYVFEVRSKRPPKNRLNALISFGNTLLYTTTLSEIYRTHLDPRIGYLHTSNFRRFSLNLDVAEIFKPILVDRLIFYLTGKQMLKKSHFEKKLDGVVLSRSGRTLFIQNFEQRMMSTIKHRELGRQVSYRRLIRMELYKLEKHLMGEADYQPFVARW
>NC_018870.1|WP_037999167.1|2466877_2467384_-|CRISPR-associated-protein-Cas4
MIGEHWPVNGTLVWYYTICHRQVWLMARQLTPDEDDDNVAIGRFIHEHSYRRDRHELAVGNIRIDLMQASRDEVLIAEIKKSSRFLESARLQLKYYLFVLKSLGLDFKGVLLVPEERKRELVTLEEEDLVEIERIIGEIRRIIDSPVPPPAVRTRWCRPCAYAEFCWA
>NC_018870.1|WP_015051480.1|2467373_2469641_-|CRISPR-associated-helicase/endonuclease-Cas3
MSPGEVYSHKGKRLEQHLLETAELAQKIARHFRLELEEGERWALLLHDLAKAHPLFQKHLLQQKGRFGHAAPSAALVLGLTGDLLCTEAVRRHHSSLENLDEAKKFWFCWDYQENACGVIGKIPVWNGAEAVMEALGHQLAKWGELLPAQADWDELIFERVEFFPPDEEKMEEAWLRLRMLYSLLVTADRYNAAVGREMEYHPLRIDQKRVEDFAASLRGRPLAEWRQQVREEVVRKAEEVLKKPGIYTLTLPTGAGKTLVGLELAMLAAERFAATGIIYVLPFISLVEQNADVARVLFKDASPVREDHYLSEVAGEEGDPENSSPQERFLSFFRYWQEPVVITTMAKFWEVLYSPKGNDTMSLHRLSRAVVILDEPQAIPSCYWQGFGKTLNLLSEKLNTTFILMTATQPEIAQGLELAPRPYFFPMIRHRFEWRRERLTVPELLGSPDVISKLLAKSALLVFNTHRSALLAYLELQSRGVTSYFLSGWVTPLDRRATLQQIREDESAGKPARLVSTQVVEAGVDLDFQFVYRDLGPLDSIIQVAGRCNRHGKREQGEVLVCELCDENGRSYAGYVYDSTLLVATKAVLKDSFDERDCPGMVAAYYRKVREITAENPLWEDISSGRWGEFHDLIEKEERGEATLVVAYEGVENDLDLLSRQAAPDEDVMRMVEQKREASRRLGLHAVSVPVKMLEEWLLRVGGMIYGAESGDILRKVSSGIYLVQGEGIGRIYSRRTGFMPPDLEAAGDGVDDW
>NC_018870.1|WP_148276019.1|2469627_2470320_-|type-I-B-CRISPR-associated-protein-Cas5
MAMFRKPYTTTSMVSFPFPPPTAVCGLIAAIVGLDHGASEGALKAEYWDRVRGMQVALGLRRPVAWFSTAVNLIKFKSPSGDMGEHIQVKHQLLKRPAYRIYVRGGEVYDELKKRLERQEFIFTPYLGVAFALAEYSYVGEFRETPVEEEAMGIDSVLPLYGDVRLDLQQSGCLHSEVVPFRLDGIRRQQETVNVIYPEYRVNSRIYLRNRGDVEVSLVGTERVAWFEPW
>NC_018870.1|WP_037999166.1|2470356_2471271_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MEFKRRREFVFLYTVVDANPNGDPLNENHPRYDEDTLQALVSDVRIKRTVRDEWVNQERLVFVDGKPKTLKTRFEELKQSTGKEKGDEVLRECIDTRLFGVTFALGNESFAWTGPVQFKWGRSLHACTFEFIQGTSAFATEGGEGKEKQQRSFRNEYKVPFALIATYGIANQHAAKYTGATEEDLDLLAEALWSGTDNLITRSKQEHKSRFYLEITYKEGFNGKIGALDEKLRLLTAEGEEPDRDAQRALRRLSQLVVDIEPLIDAVEEKSDQIDRVRAIVNKELSLLGIDRLKNLAGAVIEVR
>NC_018870.1|WP_015051483.1|2471273_2471699_-|CRISPR-associated-protein
MKLDFLSDFEDPYLQSERGKGVFLAGVLLGYMARCQVGKEGDIKKAPLFKQIDFGRMDLKRLKRQLARVPQLISAYEGMQKHSYLINRLAAEVGRLILSGNGDLGIDGNFAFTVGFGNAASYFWKIFGKEGKEELDNEGGN
>NC_018870.1|WP_015051484.1|2471695_2473132_-|CRISPR-associated-protein
MGFISAIRSLGSLTPGKGLDPYLIFPMEKGGRLIRVALKVADREAEQIDVLGVAWVDLADQIMQPEMKGKYLYRKRAGSAATWGFSPIHLMGKPKKDSNKNREAIFGKGDNWAQDKGCHLNKIRNKLLLDYEREETFSPGSVDRVMAELPEKLKGILPHLDPKSSHAFIFGLEGDDGSFLYPGEVPAFLGYFRRKLEDTLKLGEEQVRCAYCRKLCTPRSLSKVFKFSTRDKVNICHGLDKKQEPWDFPVCDDCFESISSGRDRLQMKLNNNTVLPGINIWTLPEAVGGGGGRTLKQLIASVEEGLSQDRLQSPGEKRESRYFSRLAQEGSGLVFHFIFWERNNAQELVHLMVEDVPPERLAMLERKWGEAIKAVFGDVGRDDLFTLDWAIKSLYKTLSGFAGKSEGDKKVFRDYALKVIGKMLRGERLPVAFFKQAVVERAARLAFESGSWNDVARTLLYAQAWADYMYRINQEVAV

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Crispr_ID: NC_018870_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018870_10

2455676-2458157

TypeI-B

Consensus_repeat	Method
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CRT
CCGTTTCAATTCCTCATAGGTACGCTGAAAACC	PILER-CR
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CRISPRCasFinder
GTTTCAATTCCTCATAGGTACGCTGAAAAC	PILER-CR

37 spacers

cas6,cas2,cas1,cas4,cas3,cas5,cas7,cas8b1

The CRISPR arrays of NC_018870_10

>merge|NC_018870|10|2455676-2458157|CRT,PILER-CR,CRISPRCasFinder,PILER-CR
ATCTATTTTCAGGGCAGGTACGCTGAAAACCGGTGTGTGATTGTATGAAAGATGACGATGACCAGGGCGTTTCAATTCCTCATAGGTACGCTGAAAACATGTGCCGGAGGTGTGCCCGAACTGCGCAGATATCCGTTTCAATTCCTCATAGGTACGCTGAAAACCCCGGTAGTAGACGGTAGGAACCCGATGGAAGTGGGTTTCAATTCCTCATAGGTACGCTGAAAACTTTGACTTTCTTTGACTTTTTAGTTTGCCGTCGCCAGTTTCAATTCCTCATAGGTACGCTGAAAACCTTTTTAGTTTGCCGTCGCCATAATAATCCTAGTAATCGTTTCAATTCCTCATAGGTACGCTGAAAACCAGAAACTGGGTGAAATTGTGTTGGCGGACATATACAGTTTCAATTCCTCATAGGTACGCTGAAAACCCAGAGATGCACTTTCACTTTTGAGGTGTCCAAAGGGTTTCAATTCCTCATAGGTACGCTGAAAACGAGATACTTTGACGTTGTGGATATGTTGGAATGGCCGTTTCAATTCCTCATAGGTACGCTGAAAACCATGCTTAGGATGCAGAGAGGGGATAAAAATGACATGTTTCAATTCCTCATAGGTACGCTGAAAACGGGGTAATTCTTCCTTTCTCTGCCAAGTCGATTAAGTTTCAATTCCTCATAGGTACGCTGAAAACGCACGCTTTACGGCACGCCCACCCTGACCGCGCCCCAGTTTCAATTCCTCATAGGTACGCTGAAAACACAAGCACACATTCTTTGCTGTTCTTGAAGAGATGGTTTCAATTCCTCATAGGTACGCTGAAAACGCCGACTAAGGCTGCGGCTGCGGCTGCGGCTCCTGCGTTTCAATTCCTCATAGGTACGCTGAAAACTGTGGAGTAAGGGGGGATATTGTGATAGCACTTTTTAGTTTCAATTCCTCATAGGTACGCTGAAAACAGAGCAAGGGCTTCTATCTCTTCCGTACGGGTTTCCTTGTTTCAATTCCTCATAGGTACGCTGAAAACGCGGGACTTCTATCCAGTCGATTCCCTGCTCGGTGTTTCAATTCCTCATAGGTACGCTGAAAACCCTCTTTCCTGTCTCCCAGTTATCTGGGAAACAGGGTTTCAATTCCTCATAGGTACGCTGAAAACACAGATAAGGAGTTAAGAGACTTAATTGCCGAAGTTGTTTCAATTCCTCATAGGTACGCTGAAAACCGGAATCTGCTGAACCTAATTTGATGGAGTTGTACGGGTTTCAATTCCTCATAGGTACGCTGAAAACAAAAGAAATTCAAGCTCTACCATTGCGACGCACCTCGTTTCAATTCCTCATAGGTACGCTGAAAACGGAAGGAGAACTCGAGAAGGGACTTGCTCTTCTCGGGGTTTCAATTCCTCATAGGTACGCTGAAAACTATTACATGGGAATTAGAAGAACGGGAAGGTTCTTAGTTTCAATTCCTCATAGGTACGCTGAAAACGAAGTACAGGGTGATTGCGGAATTTGTCGATTTGGAAGGTTTCAATTCCTCATAGGTACGCTGAAAACCATCTATTATAAGTAAACAATATCCTTCTTTTCCTAGTTTCAATTCCTCATAGGTACGCTGAAAACTTAGCGTGATCGAGGGCATGATGAAGCTCCTCGAAGGTTTCAATTCCTCATAGGTACGCTGAAAACAGAGAGGAAAGTGGCATATTCTCGTCCTATCGCGCCAGTTTCAATTCCTCATAGGTACGCTGAAAACCAAGAATAGAAAGTCCCTTCTCGAGATCCCCTTCCGTTTCAATTCCTCATAGGTACGCTGAAAACTTCTGTTTTGCATTTTTTGGCACACTTTTGTTGAAGTTTCAATTCCTCATAGGTACGCTGAAAACTCCATCAGGCGTGATGAGCGCAATGACGGTGCTTGCGTTTCAATTCCTCATAGGTACGCTGAAAACGGTATTATCATATTACCTGCCCCGCGGTCGGCGCTCTGTTTCAATTCCTCATAGGTACGCTGAAAACTCTGTTCAAGGTCTTTTAAAGCCGCATCGCTAAAACGTTTCAATTCCTCATAGGTACGCTGAAAACGAAGAAGTTTCCACTAAAGTTAGGAAAAAAGTCCTAGTTTCAATTCCTCATAGGTACGCTGAAAACGGTAGAGGTGAAGAAGCACCCGGCGAGCAGAGCCCAGTTTCAATTCCTCATAGGTACGCTGAAAACCGGCATCGGAATTTTAACTGGATACGAGGGGGTTGAGTTTCAATTCCTCATAGGTACGCTGAAAACAAGAGAAAAATCGGGATGATTATGGGGCTTGTATATTGTTTCAATTCCTCATAGGTACGCTGAAAACAGAAAGATGGTGAATTCATACTCAATACCGTCCCGGAGTTTCAATTCCTCATAGGTACGCTGAAAACGCATGGACTGTGAGCGGATGTACGTGCTCTGGGAGTAGTTTCAATTCCTCATACCGGAGTTCGACAC

>NC_018870|10|9|2455676-2458157|CRT
ATCTATTTTCAGGGCAGGTACGCTGAAAAC	CGGTGTGTGATTGTATGAAAGATGACGATGACCAGGGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ATGTGCCGGAGGTGTGCCCGAACTGCGCAGATATCC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCCGGTAGTAGACGGTAGGAACCCGATGGAAGTGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTTGACTTTCTTTGACTTTTTAGTTTGCCGTCGCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTTTTTAGTTTGCCGTCGCCATAATAATCCTAGTAATC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAGAAACTGGGTGAAATTGTGTTGGCGGACATATACA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCAGAGATGCACTTTCACTTTTGAGGTGTCCAAAGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAGATACTTTGACGTTGTGGATATGTTGGAATGGCC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CATGCTTAGGATGCAGAGAGGGGATAAAAATGACAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGGGTAATTCTTCCTTTCTCTGCCAAGTCGATTAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCACGCTTTACGGCACGCCCACCCTGACCGCGCCCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACAAGCACACATTCTTTGCTGTTCTTGAAGAGATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCCGACTAAGGCTGCGGCTGCGGCTGCGGCTCCTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGTGGAGTAAGGGGGGATATTGTGATAGCACTTTTTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGAGCAAGGGCTTCTATCTCTTCCGTACGGGTTTCCTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCGGGACTTCTATCCAGTCGATTCCCTGCTCGGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCTCTTTCCTGTCTCCCAGTTATCTGGGAAACAGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACAGATAAGGAGTTAAGAGACTTAATTGCCGAAGTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGGAATCTGCTGAACCTAATTTGATGGAGTTGTACGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAAAGAAATTCAAGCTCTACCATTGCGACGCACCTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAAGGAGAACTCGAGAAGGGACTTGCTCTTCTCGGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TATTACATGGGAATTAGAAGAACGGGAAGGTTCTTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAAGTACAGGGTGATTGCGGAATTTGTCGATTTGGAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CATCTATTATAAGTAAACAATATCCTTCTTTTCCTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTAGCGTGATCGAGGGCATGATGAAGCTCCTCGAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGAGAGGAAAGTGGCATATTCTCGTCCTATCGCGCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAAGAATAGAAAGTCCCTTCTCGAGATCCCCTTCC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTCTGTTTTGCATTTTTTGGCACACTTTTGTTGAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCCATCAGGCGTGATGAGCGCAATGACGGTGCTTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGTATTATCATATTACCTGCCCCGCGGTCGGCGCTCT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCTGTTCAAGGTCTTTTAAAGCCGCATCGCTAAAAC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAAGAAGTTTCCACTAAAGTTAGGAAAAAAGTCCTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGTAGAGGTGAAGAAGCACCCGGCGAGCAGAGCCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGGCATCGGAATTTTAACTGGATACGAGGGGGTTGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAGAGAAAAATCGGGATGATTATGGGGCTTGTATATT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGAAAGATGGTGAATTCATACTCAATACCGTCCCGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCATGGACTGTGAGCGGATGTACGTGCTCTGGGAGTA
GTTTCAATTCCTCATACCGGAGTTCGACAC

>NC_018870|10|10|2455690-2455840|PILER-CR
CAGGTACGCTGAAAACCGGTGTGTGATTGTATGAAAGA	TGACGATGACCAGGGCGTTTCAATTCCTCA
TAGGTACGCTGAAAACATGTGCCGGAGGTGTGCCCGAA	CTGCGCAGATATCCGTTTCAATTCCTCATAGGT
ACGCTGAAAACCCCGGTAGTAGACGGTAGGAACCCGATGGAAGTGGGTTTCAATTCCTCATAGGTACGCTGAAAACTTTGACTTTCTTTGACTTTTTAGTTTGCCGTCGCCAGTTTCAATTCCTCATAGGTACGCTGAAAACCTTTTTAGTTTGCCGTCGCCATAATAATCCTAGTAATCGTTTCAATTCCTCATAGGTACGCTGAAAAC	CAGAAACTGGGTGAAATTGTGTTGGCGGACATATACA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCAGAGATGCACTTTCACTTTTGAGGTGTCCAAAGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAGATACTTTGACGTTGTGGATATGTTGGAATGGCC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CATGCTTAGGATGCAGAGAGGGGATAAAAATGACAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGGGTAATTCTTCCTTTCTCTGCCAAGTCGATTAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCACGCTTTACGGCACGCCCACCCTGACCGCGCCCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACAAGCACACATTCTTTGCTGTTCTTGAAGAGATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCCGACTAAGGCTGCGGCTGCGGCTGCGGCTCCTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGTGGAGTAAGGGGGGATATTGTGATAGCACTTTTTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGAGCAAGGGCTTCTATCTCTTCCGTACGGGTTTCCTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCGGGACTTCTATCCAGTCGATTCCCTGCTCGGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCTCTTTCCTGTCTCCCAGTTATCTGGGAAACAGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACAGATAAGGAGTTAAGAGACTTAATTGCCGAAGTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGGAATCTGCTGAACCTAATTTGATGGAGTTGTACGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAAAGAAATTCAAGCTCTACCATTGCGACGCACCTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAAGGAGAACTCGAGAAGGGACTTGCTCTTCTCGGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TATTACATGGGAATTAGAAGAACGGGAAGGTTCTTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAAGTACAGGGTGATTGCGGAATTTGTCGATTTGGAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CATCTATTATAAGTAAACAATATCCTTCTTTTCCTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTAGCGTGATCGAGGGCATGATGAAGCTCCTCGAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGAGAGGAAAGTGGCATATTCTCGTCCTATCGCGCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAAGAATAGAAAGTCCCTTCTCGAGATCCCCTTCC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTCTGTTTTGCATTTTTTGGCACACTTTTGTTGAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCCATCAGGCGTGATGAGCGCAATGACGGTGCTTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGTATTATCATATTACCTGCCCCGCGGTCGGCGCTCT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCTGTTCAAGGTCTTTTAAAGCCGCATCGCTAAAAC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAAGAAGTTTCCACTAAAGTTAGGAAAAAAGTCCTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGTAGAGGTGAAGAAGCACCCGGCGAGCAGAGCCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGGCATCGGAATTTTAACTGGATACGAGGGGGTTGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAGAGAAAAATCGGGATGATTATGGGGCTTGTATATT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGAAAGATGGTGAATTCATACTCAATACCGTCCCGGA


>NC_018870|10|9|2455744-2458157|CRISPRCasFinder
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ATGTGCCGGAGGTGTGCCCGAACTGCGCAGATATCC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCCGGTAGTAGACGGTAGGAACCCGATGGAAGTGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTTGACTTTCTTTGACTTTTTAGTTTGCCGTCGCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTTTTTAGTTTGCCGTCGCCATAATAATCCTAGTAATC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAGAAACTGGGTGAAATTGTGTTGGCGGACATATACA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCAGAGATGCACTTTCACTTTTGAGGTGTCCAAAGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAGATACTTTGACGTTGTGGATATGTTGGAATGGCC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CATGCTTAGGATGCAGAGAGGGGATAAAAATGACAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGGGTAATTCTTCCTTTCTCTGCCAAGTCGATTAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCACGCTTTACGGCACGCCCACCCTGACCGCGCCCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACAAGCACACATTCTTTGCTGTTCTTGAAGAGATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCCGACTAAGGCTGCGGCTGCGGCTGCGGCTCCTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGTGGAGTAAGGGGGGATATTGTGATAGCACTTTTTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGAGCAAGGGCTTCTATCTCTTCCGTACGGGTTTCCTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCGGGACTTCTATCCAGTCGATTCCCTGCTCGGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCTCTTTCCTGTCTCCCAGTTATCTGGGAAACAGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACAGATAAGGAGTTAAGAGACTTAATTGCCGAAGTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGGAATCTGCTGAACCTAATTTGATGGAGTTGTACGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAAAGAAATTCAAGCTCTACCATTGCGACGCACCTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAAGGAGAACTCGAGAAGGGACTTGCTCTTCTCGGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TATTACATGGGAATTAGAAGAACGGGAAGGTTCTTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAAGTACAGGGTGATTGCGGAATTTGTCGATTTGGAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CATCTATTATAAGTAAACAATATCCTTCTTTTCCTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTAGCGTGATCGAGGGCATGATGAAGCTCCTCGAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGAGAGGAAAGTGGCATATTCTCGTCCTATCGCGCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAAGAATAGAAAGTCCCTTCTCGAGATCCCCTTCC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTCTGTTTTGCATTTTTTGGCACACTTTTGTTGAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCCATCAGGCGTGATGAGCGCAATGACGGTGCTTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGTATTATCATATTACCTGCCCCGCGGTCGGCGCTCT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCTGTTCAAGGTCTTTTAAAGCCGCATCGCTAAAAC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAAGAAGTTTCCACTAAAGTTAGGAAAAAAGTCCTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGTAGAGGTGAAGAAGCACCCGGCGAGCAGAGCCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGGCATCGGAATTTTAACTGGATACGAGGGGGTTGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAGAGAAAAATCGGGATGATTATGGGGCTTGTATATT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGAAAGATGGTGAATTCATACTCAATACCGTCCCGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCATGGACTGTGAGCGGATGTACGTGCTCTGGGAGTA
GTTTCAATTCCTCATACCGGAGTTCGACAC

>NC_018870|10|11|2456009-2458090|PILER-CR
	TGACGATGACCAGGGCGTTTCAATTCCTCA
TAGGTACGCTGAAAACATGTGCCGGAGGTGTGCCCGAA	CTGCGCAGATATCCGTTTCAATTCCTCATAGGT
ACGCTGAAAACCCCGGTAGTAGACGGTAGGAACCCGATGGAAGTGGGTTTCAATTCCTCATAGGTACGCTGAAAACTTTGACTTTCTTTGACTTTTTAGTTTGCCGTCGCCAGTTTCAATTCCTCATAGGTACGCTGAAAACCTTTTTAGTTTGCCGTCGCCATAATAATCCTAGTAATCGTTTCAATTCCTCATAGGTACGCTGAAAAC	CAGAAACTGGGTGAAATTGTGTTGGCGGACATATACA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCAGAGATGCACTTTCACTTTTGAGGTGTCCAAAGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAGATACTTTGACGTTGTGGATATGTTGGAATGGCC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CATGCTTAGGATGCAGAGAGGGGATAAAAATGACAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGGGTAATTCTTCCTTTCTCTGCCAAGTCGATTAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCACGCTTTACGGCACGCCCACCCTGACCGCGCCCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACAAGCACACATTCTTTGCTGTTCTTGAAGAGATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCCGACTAAGGCTGCGGCTGCGGCTGCGGCTCCTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGTGGAGTAAGGGGGGATATTGTGATAGCACTTTTTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGAGCAAGGGCTTCTATCTCTTCCGTACGGGTTTCCTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCGGGACTTCTATCCAGTCGATTCCCTGCTCGGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCTCTTTCCTGTCTCCCAGTTATCTGGGAAACAGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACAGATAAGGAGTTAAGAGACTTAATTGCCGAAGTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGGAATCTGCTGAACCTAATTTGATGGAGTTGTACGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAAAGAAATTCAAGCTCTACCATTGCGACGCACCTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAAGGAGAACTCGAGAAGGGACTTGCTCTTCTCGGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TATTACATGGGAATTAGAAGAACGGGAAGGTTCTTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAAGTACAGGGTGATTGCGGAATTTGTCGATTTGGAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CATCTATTATAAGTAAACAATATCCTTCTTTTCCTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTAGCGTGATCGAGGGCATGATGAAGCTCCTCGAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGAGAGGAAAGTGGCATATTCTCGTCCTATCGCGCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAAGAATAGAAAGTCCCTTCTCGAGATCCCCTTCC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTCTGTTTTGCATTTTTTGGCACACTTTTGTTGAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCCATCAGGCGTGATGAGCGCAATGACGGTGCTTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGTATTATCATATTACCTGCCCCGCGGTCGGCGCTCT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCTGTTCAAGGTCTTTTAAAGCCGCATCGCTAAAAC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAAGAAGTTTCCACTAAAGTTAGGAAAAAAGTCCTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGTAGAGGTGAAGAAGCACCCGGCGAGCAGAGCCCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGGCATCGGAATTTTAACTGGATACGAGGGGGTTGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAGAGAAAAATCGGGATGATTATGGGGCTTGTATATT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGAAAGATGGTGAATTCATACTCAATACCGTCCCGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018870.1\|WP_015051476.1\|2464856_2465594_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NC_018870.1\|WP_015051469.1\|2438070_2438394_+\|transposase	unknown	unknown	gnl\|CDD\|366690
NC_018870.1\|WP_015051478.1\|2465873_2466866_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_018870.1\|WP_015051484.1\|2471695_2473132_-\|CRISPR-associated-protein	cas8b1	pfam09484_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_018870.1\|WP_081578676.1\|2458292_2459963_+\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_018870.1\|WP_037999166.1\|2470356_2471271_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_018870.1\|WP_015051471.1\|2440644_2441883_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376773
NC_018870.1\|WP_037999167.1\|2466877_2467384_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_018870.1\|WP_015051472.1\|2448405_2449620_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018870.1\|WP_015051480.1\|2467373_2469641_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_018870.1\|WP_081578676.1\|2446079_2447750_-\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_018870.1\|WP_015051483.1\|2471273_2471699_-\|CRISPR-associated-protein	cas8b1	mkCas0119_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_018870.1\|WP_015051477.1\|2465607_2465871_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_018870.1\|WP_015051468.1\|2437832_2438030_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275209
NC_018870.1\|WP_148276019.1\|2469627_2470320_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_018870.1\|WP_015051475.1\|2452788_2453145_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NC_018870.1\|WP_015049782.1\|2453138_2453459_-\|IS66-family-insertion-sequence-hypothetical-protein	unknown	unknown	gnl\|CDD\|225511
NC_018870.1\|WP_148276018.1\|2437231_2437552_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372110
NC_018870.1\|WP_015051472.1\|2442275_2443490_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018870.1\|WP_015051470.1\|2438417_2439062_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|379098

Protein	Function_ID	Function_description	E-value
NC_018870.1\|WP_015051476.1\|2464856_2465594_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.60943e-42
NC_018870.1\|WP_015051469.1\|2438070_2438394_+\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	1.36302e-09
NC_018870.1\|WP_015051478.1\|2465873_2466866_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	8.78104e-171
NC_018870.1\|WP_015051484.1\|2471695_2473132_-\|CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.3023e-20
NC_018870.1\|WP_081578676.1\|2458292_2459963_+\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.8014e-28
NC_018870.1\|WP_037999166.1\|2470356_2471271_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	8.44442e-77
NC_018870.1\|WP_015051471.1\|2440644_2441883_-\|IS110-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	5.273e-26
NC_018870.1\|WP_037999167.1\|2466877_2467384_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.89318e-70
NC_018870.1\|WP_015051472.1\|2448405_2449620_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.31767e-41
NC_018870.1\|WP_015051480.1\|2467373_2469641_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	3.72763e-54
NC_018870.1\|WP_081578676.1\|2446079_2447750_-\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.8014e-28
NC_018870.1\|WP_015051483.1\|2471273_2471699_-\|CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	7.70598e-09
NC_018870.1\|WP_015051477.1\|2465607_2465871_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.43479e-28
NC_018870.1\|WP_015051468.1\|2437832_2438030_+\|hypothetical-protein	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	4.96046e-15
NC_018870.1\|WP_148276019.1\|2469627_2470320_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	4.95478e-37
NC_018870.1\|WP_015051475.1\|2452788_2453145_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	1.30076e-55
NC_018870.1\|WP_015049782.1\|2453138_2453459_-\|IS66-family-insertion-sequence-hypothetical-protein	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.000769281
NC_018870.1\|WP_148276018.1\|2437231_2437552_+\|hypothetical-protein	gnl\|CDD\|372110	pfam12441, CopG_antitoxin, CopG antitoxin of type II toxin-antitoxin system. CopG antitoxin is a member of a type II toxin-antitoxin system family found in bacteria and archaea. Most antitoxins encoded by the relBE and parDE loci belong to the MetJ/Arc/CopG family of dimeric proteins which bind DNA through N-terminal ribbon-helix-helix (RHH) motifs. The toxin for CopG proteins falls into the family BrnT_toxin, pfam04365.	8.50953e-11
NC_018870.1\|WP_015051472.1\|2442275_2443490_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.31767e-41
NC_018870.1\|WP_015051470.1\|2438417_2439062_+\|IS3-family-transposase	gnl\|CDD\|379098	pfam13276, HTH_21, HTH-like domain. This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.	7.64926e-08

>NC_018870.1|WP_015049782.1|2453138_2453459_-|IS66-family-insertion-sequence-hypothetical-protein
MTRAELQKLWEARIAEYRESGQSVKEWCASHEGINPRQLWYWLRKFKNQTPAPPEISNRWLSVEISEEDSLEQALLVKIGPASIEVRPGFDPALLTKVVQVLMALC
>NC_018870.1|WP_015051475.1|2452788_2453145_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MLNEAGIDRVYLACGATDLRKSIDGLAVLVKEGFELDPFSSCLFVFCNRKRDKLKILHWEHNGFWLYYRRLEKGKFIWPQDTTSSTITISRRELRWLLDGLPLKQPKAHPEVKARTIL
>NC_018870.1|WP_015051472.1|2448405_2449620_+|IS110-family-transposase
MDVVFPYCCGLDVHKNSVVACVITPDEKEIRTFGTMTRDLLNLADWLTSKGCTHVAMESTGVYWKPIYNILEQYQLELLVVNAKHIKAVPGRKTDVKDAEWIADLLRHGLLKGSYIPDREQRELRELVGYRKSLVEERAREVNRIQKTLEGAGIKLSSVATDVVGVSGRAMIEGIISGIDDPAVLADFAQKKLKKKKEQLEQALFGLVGKHQRLLLAAQLRHIDYLDQEIARLDQQIEERMRPFEAELALLDTIPGVGRRTSQVILACIGADMSRFPSAAHLSSWAGVAPGNNESAGKRKSGKTTKGNTLLHTTLIQAARAASRTKNTYLSALYHRVAARRGANRAAVAVAHSILVSVYYMLIRRVPYHDLGGDYFEKRNSKAVVNRAVKQLEQLGYRVSIEVA
>NC_018870.1|WP_081578676.1|2446079_2447750_-|IS1634-family-transposase
MWYNVDMYIRTIQRKNKDGSVVRYIQLAHNQWDPQARCAKAKVLFNFGREEEVDREALKRLVKSINRFLGPGETLRYEAETGAAPLKFITSRPLGGAWVLDRLWEELGIKGVLETLLKKRQYKTPVERAIFAMAANRALDPMSKRGVEEWVKEDAVIPGVEEIPLQQLYRAMDFLLENEAELQKQVYYSVANLLNLEVDILYFDTTSTYFEIEDEDEDGGLRRRGHSKDHRPDLPQAVIGLAVTRDGIPVRCWVWPGNTADISVVEQVKKDLIGWKLGRVITVLDRGFNSEDNLRCLQRAGGHYIAGEKLRSGKENTVQALKRGGRYQTVRDNLEVKEIVVGNGEARERYILVRNPEEAARDKARREKIIKELEEQLPHIKTHAKAVCELMAHPVYGRYLKLDSRSLPKIDRAKIREEEKLDGKYLLRTSDDTLSAEDVALGYKQLLLVEDAFRTLKSRLELRPVYHRLEDRIRSHVLLCWLALLLIRIAENRTGQTWCSLRATLQRMQLGEFSGTAGQVRQRTETTPAQKQIFKALAVKEPPLLFSINPTAKKNA
>NC_018870.1|WP_015051472.1|2442275_2443490_+|IS110-family-transposase
MDVVFPYCCGLDVHKNSVVACVITPDEKEIRTFGTMTRDLLNLADWLTSKGCTHVAMESTGVYWKPIYNILEQYQLELLVVNAKHIKAVPGRKTDVKDAEWIADLLRHGLLKGSYIPDREQRELRELVGYRKSLVEERAREVNRIQKTLEGAGIKLSSVATDVVGVSGRAMIEGIISGIDDPAVLADFAQKKLKKKKEQLEQALFGLVGKHQRLLLAAQLRHIDYLDQEIARLDQQIEERMRPFEAELALLDTIPGVGRRTSQVILACIGADMSRFPSAAHLSSWAGVAPGNNESAGKRKSGKTTKGNTLLHTTLIQAARAASRTKNTYLSALYHRVAARRGANRAAVAVAHSILVSVYYMLIRRVPYHDLGGDYFEKRNSKAVVNRAVKQLEQLGYRVSIEVA
>NC_018870.1|WP_015051471.1|2440644_2441883_-|IS110-family-transposase
MKLFVGIDVSMKDFKARMFDAEGEEIAKRMRYKNDDPGAESFVKYLVEICGANEVDSLRIGMESTSVYGWHLQMRLAGEPLLASFHPQVYVFNPKVIANFRKQYVDIPKDDWFDCLVIADRLRFGRLPESCQVDFRYLPLQRLTRFRYHLIQTITREKNYFLTNLFLKFNTICQDKVLSDIFGATSEAILTEFLSPEEIAARPLDELIDFLMEKGKSHFSNPEATAKALKHAAACAYRLHGSLLEPVNLILATSLQTICTLEQQVKSIDRAIEKELSHFPNTLQSMPGMGPVCTAGIIAEIGDIHRFDNEKAVAKFAGLTWRKHQSGEFEADDTPLTKTGNVYLRYYFVMAADSVRKWDPRFAEFYARKFKESSTHHHRRALVLTARKLVRVVDALLRSNQLYVPQGQRKVV
>NC_018870.1|WP_015051470.1|2438417_2439062_+|IS3-family-transposase
MGYKVSLVLRIIGISRSTYYPNLKRQPKPRIFAGGRPKSHYTFTSDNKVVSNEQVKEWLCELITAEGFAYGYLKLTHCLRRKFHLIINKKKVYRLCKELDILRPQRKIKRKHPRRLARNRVITASNQLWEADLKYGYIAGEDRFFFIMPIIDVFDRCIVAYHIGLSCEAKDARVMSLPAMPKRMQRLSTSSTFTTKPGFIQQLNTYHRWNAINC
>NC_018870.1|WP_015051469.1|2438070_2438394_+|transposase
MNRKQYSPEMKMQIVKETLETGNASIVARRHDIAPSLVARWARCYKRYGTFYPQKEVPGTNGSCIPPDYKKITKENEQLKKLLGEKDLEIAILRDLLKKTNLPFPIK
>NC_018870.1|WP_015051468.1|2437832_2438030_+|hypothetical-protein
MEKVLERSNMLRALRRVKSNKGADGVDGMEIKSLRPYLKEHWPKIKEELLKGTYKLFSPLTRLNS
>NC_018870.1|WP_148276018.1|2437231_2437552_+|hypothetical-protein
MAKKKELPEFKGDEIPEFASEEEAAEFFDRHSFAEAMERGVLAPDDPAEPDPELAATSKTKRVTLRLRVSQIEAAKEIAKRKDIPYQTLLRSWIAEGIRREMEGKG
>NC_018870.1|WP_081578676.1|2458292_2459963_+|IS1634-family-transposase
MWYNVDMYIRTIQRKNKDGSVVRYIQLAHNQWDPQARCAKAKVLFNFGREEEVDREALKRLVKSINRFLGPGETLRYEAETGAAPLKFITSRPLGGAWVLDRLWEELGIKGVLETLLKKRQYKTPVERAIFAMAANRALDPMSKRGVEEWVKEDAVIPGVEEIPLQQLYRAMDFLLENEAELQKQVYYSVANLLNLEVDILYFDTTSTYFEIEDEDEDGGLRRRGHSKDHRPDLPQAVIGLAVTRDGIPVRCWVWPGNTADISVVEQVKKDLIGWKLGRVITVLDRGFNSEDNLRCLQRAGGHYIAGEKLRSGKENTVQALKRGGRYQTVRDNLEVKEIVVGNGEARERYILVRNPEEAARDKARREKIIKELEEQLPHIKTHAKAVCELMAHPVYGRYLKLDSRSLPKIDRAKIREEEKLDGKYLLRTSDDTLSAEDVALGYKQLLLVEDAFRTLKSRLELRPVYHRLEDRIRSHVLLCWLALLLIRIAENRTGQTWCSLRATLQRMQLGEFSGTAGQVRQRTETTPAQKQIFKALAVKEPPLLFSINPTAKKNA
>NC_018870.1|WP_015051476.1|2464856_2465594_-|CRISPR-associated-endoribonuclease-Cas6
MRLIVEFRATENERITLPLQYNKAVQGMIYQRVREHLPELHDRGFVSAGRVFRLFVFSRIEGSGVKIINGMISFNSPVRIKIGSPNNNFLECLANSLLRTPQIDIGGSPLVVESVAIARNPDFSSGRVKVRAISPITVYSTLMSADGRKKTYYYHPEEKEFSDQIRNNIIKKGALLGVDDKEAYFTIEPYRVRNTDLKTVYYKDYVVKGWLGQYLLRGTPELLNIAYDAGIGAKNSQGFGMVEII
>NC_018870.1|WP_015051477.1|2465607_2465871_-|CRISPR-associated-endonuclease-Cas2
MFVIEVYDVNEKRVAKVLKVSRKYLYWVQNSVLEGEISEANFRRLKEELLEIIDLKEDSLIFYTFRTTKYSERQCFGVLKGGEETIF
>NC_018870.1|WP_015051478.1|2465873_2466866_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MRKSIYLLNSGELRRENNTICLITDEGKRFLPVEDIGEIHVFGEVDLNKRLLEFLSEKEIILHYYNHYDYYMGSFYPREHFNSGYMTVKQAEHYINPELRICLARAFVTGAVKNIRQVLMYYRNRGKEVGSAFERIEKLMGEIDSASSVDELMAYEGNIRDAYYGTFDLIIDNPDYVFEVRSKRPPKNRLNALISFGNTLLYTTTLSEIYRTHLDPRIGYLHTSNFRRFSLNLDVAEIFKPILVDRLIFYLTGKQMLKKSHFEKKLDGVVLSRSGRTLFIQNFEQRMMSTIKHRELGRQVSYRRLIRMELYKLEKHLMGEADYQPFVARW
>NC_018870.1|WP_037999167.1|2466877_2467384_-|CRISPR-associated-protein-Cas4
MIGEHWPVNGTLVWYYTICHRQVWLMARQLTPDEDDDNVAIGRFIHEHSYRRDRHELAVGNIRIDLMQASRDEVLIAEIKKSSRFLESARLQLKYYLFVLKSLGLDFKGVLLVPEERKRELVTLEEEDLVEIERIIGEIRRIIDSPVPPPAVRTRWCRPCAYAEFCWA
>NC_018870.1|WP_015051480.1|2467373_2469641_-|CRISPR-associated-helicase/endonuclease-Cas3
MSPGEVYSHKGKRLEQHLLETAELAQKIARHFRLELEEGERWALLLHDLAKAHPLFQKHLLQQKGRFGHAAPSAALVLGLTGDLLCTEAVRRHHSSLENLDEAKKFWFCWDYQENACGVIGKIPVWNGAEAVMEALGHQLAKWGELLPAQADWDELIFERVEFFPPDEEKMEEAWLRLRMLYSLLVTADRYNAAVGREMEYHPLRIDQKRVEDFAASLRGRPLAEWRQQVREEVVRKAEEVLKKPGIYTLTLPTGAGKTLVGLELAMLAAERFAATGIIYVLPFISLVEQNADVARVLFKDASPVREDHYLSEVAGEEGDPENSSPQERFLSFFRYWQEPVVITTMAKFWEVLYSPKGNDTMSLHRLSRAVVILDEPQAIPSCYWQGFGKTLNLLSEKLNTTFILMTATQPEIAQGLELAPRPYFFPMIRHRFEWRRERLTVPELLGSPDVISKLLAKSALLVFNTHRSALLAYLELQSRGVTSYFLSGWVTPLDRRATLQQIREDESAGKPARLVSTQVVEAGVDLDFQFVYRDLGPLDSIIQVAGRCNRHGKREQGEVLVCELCDENGRSYAGYVYDSTLLVATKAVLKDSFDERDCPGMVAAYYRKVREITAENPLWEDISSGRWGEFHDLIEKEERGEATLVVAYEGVENDLDLLSRQAAPDEDVMRMVEQKREASRRLGLHAVSVPVKMLEEWLLRVGGMIYGAESGDILRKVSSGIYLVQGEGIGRIYSRRTGFMPPDLEAAGDGVDDW
>NC_018870.1|WP_148276019.1|2469627_2470320_-|type-I-B-CRISPR-associated-protein-Cas5
MAMFRKPYTTTSMVSFPFPPPTAVCGLIAAIVGLDHGASEGALKAEYWDRVRGMQVALGLRRPVAWFSTAVNLIKFKSPSGDMGEHIQVKHQLLKRPAYRIYVRGGEVYDELKKRLERQEFIFTPYLGVAFALAEYSYVGEFRETPVEEEAMGIDSVLPLYGDVRLDLQQSGCLHSEVVPFRLDGIRRQQETVNVIYPEYRVNSRIYLRNRGDVEVSLVGTERVAWFEPW
>NC_018870.1|WP_037999166.1|2470356_2471271_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MEFKRRREFVFLYTVVDANPNGDPLNENHPRYDEDTLQALVSDVRIKRTVRDEWVNQERLVFVDGKPKTLKTRFEELKQSTGKEKGDEVLRECIDTRLFGVTFALGNESFAWTGPVQFKWGRSLHACTFEFIQGTSAFATEGGEGKEKQQRSFRNEYKVPFALIATYGIANQHAAKYTGATEEDLDLLAEALWSGTDNLITRSKQEHKSRFYLEITYKEGFNGKIGALDEKLRLLTAEGEEPDRDAQRALRRLSQLVVDIEPLIDAVEEKSDQIDRVRAIVNKELSLLGIDRLKNLAGAVIEVR
>NC_018870.1|WP_015051483.1|2471273_2471699_-|CRISPR-associated-protein
MKLDFLSDFEDPYLQSERGKGVFLAGVLLGYMARCQVGKEGDIKKAPLFKQIDFGRMDLKRLKRQLARVPQLISAYEGMQKHSYLINRLAAEVGRLILSGNGDLGIDGNFAFTVGFGNAASYFWKIFGKEGKEELDNEGGN
>NC_018870.1|WP_015051484.1|2471695_2473132_-|CRISPR-associated-protein
MGFISAIRSLGSLTPGKGLDPYLIFPMEKGGRLIRVALKVADREAEQIDVLGVAWVDLADQIMQPEMKGKYLYRKRAGSAATWGFSPIHLMGKPKKDSNKNREAIFGKGDNWAQDKGCHLNKIRNKLLLDYEREETFSPGSVDRVMAELPEKLKGILPHLDPKSSHAFIFGLEGDDGSFLYPGEVPAFLGYFRRKLEDTLKLGEEQVRCAYCRKLCTPRSLSKVFKFSTRDKVNICHGLDKKQEPWDFPVCDDCFESISSGRDRLQMKLNNNTVLPGINIWTLPEAVGGGGGRTLKQLIASVEEGLSQDRLQSPGEKRESRYFSRLAQEGSGLVFHFIFWERNNAQELVHLMVEDVPPERLAMLERKWGEAIKAVFGDVGRDDLFTLDWAIKSLYKTLSGFAGKSEGDKKVFRDYALKVIGKMLRGERLPVAFFKQAVVERAARLAFESGSWNDVARTLLYAQAWADYMYRINQEVAV

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Crispr_ID: NC_018870_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018870_11

2460040-2463469

TypeIII

Consensus_repeat	Method
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CRT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	PILER-CR
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CRISPRCasFinder

51 spacers

cas6,cas2,cas1,cas4,cas3,cas5,cas7,cas8b1,csx1

The CRISPR arrays of NC_018870_11

>merge|NC_018870|11|2460040-2463469|CRT,PILER-CR,CRISPRCasFinder
TCGAACTCCGGTCATAGGTACGCTGAAAACGCCGAGAAAATGTTCTCGGTGGCCTGGGATTACGCTGTTTCAATTCCTCATAGGTACGCTGAAAACGATGCCCTCCTTTCTTGCGATTGAACGGCAAGAAGTGGTTTCAATTCCTCATAGGTACGCTGAAAACGGGGGTGTTTCCAGCCGTAATTGATAATCCAAAGTGTTTCAATTCCTCATAGGTACGCTGAAAACAATCAAAGCATGTCGCCCGAGGCTCATTGACGAGGGTTTCAATTCCTCATAGGTACGCTGAAAACTTTCTGGGCACTTTCGGATGTCCAGAAGTACCCGAAGTTTCAATTCCTCATAGGTACGCTGAAAACTGCATCTGAAGCACTTAAATACGCGAAGAAGCTCAAGTTTCAATTCCTCATAGGTACGCTGAAAACGTAATTACTCCCCTTACCCAGATAGCACCCAAGCATCGGTTTCAATTCCTCATAGGTACGCTGAAAACGTGCACTGATGGTCGTTTCTGCCTGGCCTGTTTTCACGTTTCAATTCCTCATAGGTACGCTGAAAACACGCAAAAAACGTTTGTCCTCTTACTGATGTAGAATGTTTCAATTCCTCATAGGTACGCTGAAAACTCTCCGAATGCCCGGCTAAAAAGCGGAAGGCTTCTGTTTCAATTCCTCATAGGTACGCTGAAAACCGAAGCATGGTAAACATGATAACGACCATCATAGAGTTTCAATTCCTCATAGGTACGCTGAAAACTTTCGTTCCCCCCTTTGTTTGTTTCCTGTTTCCATTGTAGTTTCAATTCCTCATAGGTACGCTGAAAACCTCCTCTCTCACTTCTTTCGTCTTGGTGTCAAATCGTTTCAATTCCTCATAGGTACGCTGAAAACTGCGGGAGCGCCTGGACTACTACGAGGACTACTCAGGTTTCAATTCCTCATAGGTACGCTGAAAACGGTTCGGCGGGGCGTGGGATGCATACGGGGACGAGGAGTTTCAATTCCTCATAGGTACGCTGAAAACCTTGAAGAAGCCTTTTACGTGGTAGTTCATAAGATGGTTTCAATTCCTCATAGGTACGCTGAAAACAGGGGTATTATGTTGCAGTTCCGGAATTGCACCCGTGTTTCAATTCCTCATAGGTACGCTGAAAACGCAACCGAACGCCTTACCAGTTGTTGGAGATTGATGAGTTTCAATTCCTCATAGGTACGCTGAAAACCAAAGAAGAACTGACCAAGATGGTGGCTGATGCGGTGTTTCAATTCCTCATAGGTACGCTGAAAACGAAGAAACGCGAGCGGACGATTTGGCCTATAAAGAAAGTTTCAATTCCTCATAGGTACGCTGAAAACTCAAAAGGTTGCGGGCCGAGCGGGAGGCCGCGGCCGAAGTTTCAATTCCTCATAGGTACGCTGAAAACTGAAAGAGCGGGTAGCAAAAGAATATATGGAATCAGTTTCAATTCCTCATAGGTACGCTGAAAACCGGGTCTGGAAATTCCATCCTCAAGAGTTCGGATTGGTTTCAATTCCTCATAGGTACGCTGAAAACGGCAGTATAAAGAAAAGCGTTTGCCTGTCTATTGTGGGTTTCAATTCCTCATAGGTACGCTGAAAACTAAGAACGCGATAGGTTGAAAGCGGAGTTACAAACATGTTTCAATTCCTCATAGGTACGCTGAAAACGGAACGGATTGTGCTTTCTACAATCTGTTTGATATCCCGGGTTTCAATTCCTCATAGGTACGCTGAAAACGACCGGGATTCTGGTTGCTTACGGCGTTGGATCCGCGTTTCAATTCCTCATAGGTACGCTGAAAACTATCGAGAGATGTACCTGCGGCGGCATCCCTTATGCGGTTTCAATTCCTCATAGGTACGCTGAAAACCCAATGTTGGGCACCGAAATGGTAAGCTCTGTGCCATGGTTTCAATTCCTCATAGGTACGCTGAAAACGATACGTTACCGTCCCCTTCGTCCTTCTTGGCACTTTCGTTTCAATTCCTCATAGGTACGCTGAAAACCAGGCCTGGTTAATTTATGCTGAACACTTCGGTGGTCGGTTTCAATTCCTCATAGGTACGCTGAAAACTCCTGTAGCCTTTACTGCGGGTCTTCGTTCAATGCCGTTTCAATTCCTCATAGGTACGCTGAAAACGCATTCCGCCCCAGCCGCCGGCGATCTGGGTACTGGTTTGTTTCAATTCCTCATAGGTACGCTGAAAACCTGACCACGATGAACGGTTTCTCCGCATCCGGCCTTAGTTTCAATTCCTCATAGGTACGCTGAAAACATTTTCCACTCTTCATCGAACTCTTTCTCGTGGATGGTTTCAATTCCTCATAGGTACGCTGAAAACGGGCAAGTTCTGCGGCAACGGGAGCAAGGGCATCGGTTTCAATTCCTCATAGGTACGCTGAAAACGCAGCTTTAGCACCTTCAATTGTTGTAGCAACTTCTGGTTTCAATTCCTCATAGGTACGCTGAAAACGTGGATAAAGTCCTTCTCCGGGGCGAGAAGGAAGAAGTTTCAATTCCTCATAGGTACGCTGAAAACAAAAATTCCTCTTTTTCCTGGATCGTCGGGTTCATTTGTTTCAATTCCTCATAGGTACGCTGAAAACAAACGTGTTGATTCGGCAAGATATTCAAGTTCTTTATTTTGTTTCAATTCCTCATAGGTACGCTGAAAACCGGCGATGTAAACGACGACTACGGTTACAGTTATGTGTTTCAATTCCTCATAGGTACGCTGAAAACCACGGGATATTCCGGCAACCCTGGCTGGAATACCGATGTTTCAATTCCTCATAGGTACGCTGAAAACGCTGCCGTAAGCCAGGTTGTGTTCGGCCCGGATCTGTTGTTTCAATTCCTCATAGGTACGCTGAAAACACTGCTCTTCCCAAAGGCTTAGCCCCCAGGTAGCAGTGTTTCAATTCCTCATAGGTACGCTGAAAACTGCGAGCCCCTCAGTCCAGAGCCCATGCCTCCGGAGTTTCAATTCCTCATAGGTACGCTGAAAACCGAGCCGGCAGACGAACGGACACTGCGATATATGAAGGTTTCAATTCCTCATAGGTACGCTGAAAACATCACACAGATTACCGAGTTTTTGCCTGAGTTCTTGGTTTCAATTCCTCATAGGTACGCTGAAAACGGCTCACCTTGAGATTTCTGCCGCCCCTGAGTCCTAGTTTCAATTCCTCATAGGTACGCTGAAAACAAAAACTATATGATGCACTATGCCGGGGCACTTCAAGTTTCAATTCCTCATAGGTACGCTGAAAACTGAAACCTGGCGTCAGGTTGTCATCGGCCCAAAGGGGTTTCAATTCCTCATAGGTACGCTGAAAACCGGACCGCTTCAACCCCAGGCAGGAGGTTTTTGACCTGGTTTCAATTCCTCATAGACCACCATGCCGC

>NC_018870|11|10|2460040-2463469|CRT
TCGAACTCCGGTCATAGGTACGCTGAAAAC	GCCGAGAAAATGTTCTCGGTGGCCTGGGATTACGCT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GATGCCCTCCTTTCTTGCGATTGAACGGCAAGAAGTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGGGGTGTTTCCAGCCGTAATTGATAATCCAAAGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AATCAAAGCATGTCGCCCGAGGCTCATTGACGAGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTTCTGGGCACTTTCGGATGTCCAGAAGTACCCGAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGCATCTGAAGCACTTAAATACGCGAAGAAGCTCAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTAATTACTCCCCTTACCCAGATAGCACCCAAGCATCG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTGCACTGATGGTCGTTTCTGCCTGGCCTGTTTTCAC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACGCAAAAAACGTTTGTCCTCTTACTGATGTAGAAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCTCCGAATGCCCGGCTAAAAAGCGGAAGGCTTCT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGAAGCATGGTAAACATGATAACGACCATCATAGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTTCGTTCCCCCCTTTGTTTGTTTCCTGTTTCCATTGTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTCCTCTCTCACTTCTTTCGTCTTGGTGTCAAATC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGCGGGAGCGCCTGGACTACTACGAGGACTACTCAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGTTCGGCGGGGCGTGGGATGCATACGGGGACGAGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTTGAAGAAGCCTTTTACGTGGTAGTTCATAAGATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGGGGTATTATGTTGCAGTTCCGGAATTGCACCCGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCAACCGAACGCCTTACCAGTTGTTGGAGATTGATGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAAAGAAGAACTGACCAAGATGGTGGCTGATGCGGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAAGAAACGCGAGCGGACGATTTGGCCTATAAAGAAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCAAAAGGTTGCGGGCCGAGCGGGAGGCCGCGGCCGAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGAAAGAGCGGGTAGCAAAAGAATATATGGAATCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGGGTCTGGAAATTCCATCCTCAAGAGTTCGGATTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGCAGTATAAAGAAAAGCGTTTGCCTGTCTATTGTGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TAAGAACGCGATAGGTTGAAAGCGGAGTTACAAACAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAACGGATTGTGCTTTCTACAATCTGTTTGATATCCCGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GACCGGGATTCTGGTTGCTTACGGCGTTGGATCCGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TATCGAGAGATGTACCTGCGGCGGCATCCCTTATGCG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCAATGTTGGGCACCGAAATGGTAAGCTCTGTGCCATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GATACGTTACCGTCCCCTTCGTCCTTCTTGGCACTTTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAGGCCTGGTTAATTTATGCTGAACACTTCGGTGGTCG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCCTGTAGCCTTTACTGCGGGTCTTCGTTCAATGCC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCATTCCGCCCCAGCCGCCGGCGATCTGGGTACTGGTTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTGACCACGATGAACGGTTTCTCCGCATCCGGCCTTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ATTTTCCACTCTTCATCGAACTCTTTCTCGTGGATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGGCAAGTTCTGCGGCAACGGGAGCAAGGGCATCG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCAGCTTTAGCACCTTCAATTGTTGTAGCAACTTCTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTGGATAAAGTCCTTCTCCGGGGCGAGAAGGAAGAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAAAATTCCTCTTTTTCCTGGATCGTCGGGTTCATTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAACGTGTTGATTCGGCAAGATATTCAAGTTCTTTATTTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGGCGATGTAAACGACGACTACGGTTACAGTTATGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CACGGGATATTCCGGCAACCCTGGCTGGAATACCGAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCTGCCGTAAGCCAGGTTGTGTTCGGCCCGGATCTGTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACTGCTCTTCCCAAAGGCTTAGCCCCCAGGTAGCAGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGCGAGCCCCTCAGTCCAGAGCCCATGCCTCCGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGAGCCGGCAGACGAACGGACACTGCGATATATGAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ATCACACAGATTACCGAGTTTTTGCCTGAGTTCTTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGCTCACCTTGAGATTTCTGCCGCCCCTGAGTCCTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAAAACTATATGATGCACTATGCCGGGGCACTTCAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGAAACCTGGCGTCAGGTTGTCATCGGCCCAAAGGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGGACCGCTTCAACCCCAGGCAGGAGGTTTTTGACCTG
GTTTCAATTCCTCATAGACCACCATGCCGC

>NC_018870|11|12|2460106-2463401|PILER-CR
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GATGCCCTCCTTTCTTGCGATTGAACGGCAAGAAGTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGGGGTGTTTCCAGCCGTAATTGATAATCCAAAGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AATCAAAGCATGTCGCCCGAGGCTCATTGACGAGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTTCTGGGCACTTTCGGATGTCCAGAAGTACCCGAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGCATCTGAAGCACTTAAATACGCGAAGAAGCTCAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTAATTACTCCCCTTACCCAGATAGCACCCAAGCATCG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTGCACTGATGGTCGTTTCTGCCTGGCCTGTTTTCAC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACGCAAAAAACGTTTGTCCTCTTACTGATGTAGAAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCTCCGAATGCCCGGCTAAAAAGCGGAAGGCTTCT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGAAGCATGGTAAACATGATAACGACCATCATAGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTTCGTTCCCCCCTTTGTTTGTTTCCTGTTTCCATTGTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTCCTCTCTCACTTCTTTCGTCTTGGTGTCAAATC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGCGGGAGCGCCTGGACTACTACGAGGACTACTCAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGTTCGGCGGGGCGTGGGATGCATACGGGGACGAGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTTGAAGAAGCCTTTTACGTGGTAGTTCATAAGATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGGGGTATTATGTTGCAGTTCCGGAATTGCACCCGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCAACCGAACGCCTTACCAGTTGTTGGAGATTGATGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAAAGAAGAACTGACCAAGATGGTGGCTGATGCGGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAAGAAACGCGAGCGGACGATTTGGCCTATAAAGAAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCAAAAGGTTGCGGGCCGAGCGGGAGGCCGCGGCCGAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGAAAGAGCGGGTAGCAAAAGAATATATGGAATCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGGGTCTGGAAATTCCATCCTCAAGAGTTCGGATTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGCAGTATAAAGAAAAGCGTTTGCCTGTCTATTGTGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TAAGAACGCGATAGGTTGAAAGCGGAGTTACAAACAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAACGGATTGTGCTTTCTACAATCTGTTTGATATCCCGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GACCGGGATTCTGGTTGCTTACGGCGTTGGATCCGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TATCGAGAGATGTACCTGCGGCGGCATCCCTTATGCG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCAATGTTGGGCACCGAAATGGTAAGCTCTGTGCCATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GATACGTTACCGTCCCCTTCGTCCTTCTTGGCACTTTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAGGCCTGGTTAATTTATGCTGAACACTTCGGTGGTCG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCCTGTAGCCTTTACTGCGGGTCTTCGTTCAATGCC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCATTCCGCCCCAGCCGCCGGCGATCTGGGTACTGGTTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTGACCACGATGAACGGTTTCTCCGCATCCGGCCTTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ATTTTCCACTCTTCATCGAACTCTTTCTCGTGGATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGGCAAGTTCTGCGGCAACGGGAGCAAGGGCATCG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCAGCTTTAGCACCTTCAATTGTTGTAGCAACTTCTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTGGATAAAGTCCTTCTCCGGGGCGAGAAGGAAGAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAAAATTCCTCTTTTTCCTGGATCGTCGGGTTCATTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAACGTGTTGATTCGGCAAGATATTCAAGTTCTTTATTTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGGCGATGTAAACGACGACTACGGTTACAGTTATGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CACGGGATATTCCGGCAACCCTGGCTGGAATACCGAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCTGCCGTAAGCCAGGTTGTGTTCGGCCCGGATCTGTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACTGCTCTTCCCAAAGGCTTAGCCCCCAGGTAGCAGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGCGAGCCCCTCAGTCCAGAGCCCATGCCTCCGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGAGCCGGCAGACGAACGGACACTGCGATATATGAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ATCACACAGATTACCGAGTTTTTGCCTGAGTTCTTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGCTCACCTTGAGATTTCTGCCGCCCCTGAGTCCTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAAAACTATATGATGCACTATGCCGGGGCACTTCAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGAAACCTGGCGTCAGGTTGTCATCGGCCCAAAGGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC

>NC_018870|11|10|2460106-2463402|CRISPRCasFinder
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GATGCCCTCCTTTCTTGCGATTGAACGGCAAGAAGTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGGGGTGTTTCCAGCCGTAATTGATAATCCAAAGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AATCAAAGCATGTCGCCCGAGGCTCATTGACGAGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTTCTGGGCACTTTCGGATGTCCAGAAGTACCCGAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGCATCTGAAGCACTTAAATACGCGAAGAAGCTCAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTAATTACTCCCCTTACCCAGATAGCACCCAAGCATCG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTGCACTGATGGTCGTTTCTGCCTGGCCTGTTTTCAC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACGCAAAAAACGTTTGTCCTCTTACTGATGTAGAAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCTCCGAATGCCCGGCTAAAAAGCGGAAGGCTTCT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGAAGCATGGTAAACATGATAACGACCATCATAGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTTCGTTCCCCCCTTTGTTTGTTTCCTGTTTCCATTGTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTCCTCTCTCACTTCTTTCGTCTTGGTGTCAAATC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGCGGGAGCGCCTGGACTACTACGAGGACTACTCAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGTTCGGCGGGGCGTGGGATGCATACGGGGACGAGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTTGAAGAAGCCTTTTACGTGGTAGTTCATAAGATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AGGGGTATTATGTTGCAGTTCCGGAATTGCACCCGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCAACCGAACGCCTTACCAGTTGTTGGAGATTGATGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAAAGAAGAACTGACCAAGATGGTGGCTGATGCGGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAAGAAACGCGAGCGGACGATTTGGCCTATAAAGAAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCAAAAGGTTGCGGGCCGAGCGGGAGGCCGCGGCCGAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGAAAGAGCGGGTAGCAAAAGAATATATGGAATCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGGGTCTGGAAATTCCATCCTCAAGAGTTCGGATTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGCAGTATAAAGAAAAGCGTTTGCCTGTCTATTGTGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TAAGAACGCGATAGGTTGAAAGCGGAGTTACAAACAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGAACGGATTGTGCTTTCTACAATCTGTTTGATATCCCGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GACCGGGATTCTGGTTGCTTACGGCGTTGGATCCGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TATCGAGAGATGTACCTGCGGCGGCATCCCTTATGCG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCAATGTTGGGCACCGAAATGGTAAGCTCTGTGCCATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GATACGTTACCGTCCCCTTCGTCCTTCTTGGCACTTTC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CAGGCCTGGTTAATTTATGCTGAACACTTCGGTGGTCG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCCTGTAGCCTTTACTGCGGGTCTTCGTTCAATGCC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCATTCCGCCCCAGCCGCCGGCGATCTGGGTACTGGTTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CTGACCACGATGAACGGTTTCTCCGCATCCGGCCTTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ATTTTCCACTCTTCATCGAACTCTTTCTCGTGGATG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGGCAAGTTCTGCGGCAACGGGAGCAAGGGCATCG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCAGCTTTAGCACCTTCAATTGTTGTAGCAACTTCTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTGGATAAAGTCCTTCTCCGGGGCGAGAAGGAAGAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAAAATTCCTCTTTTTCCTGGATCGTCGGGTTCATTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAACGTGTTGATTCGGCAAGATATTCAAGTTCTTTATTTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGGCGATGTAAACGACGACTACGGTTACAGTTATGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CACGGGATATTCCGGCAACCCTGGCTGGAATACCGAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GCTGCCGTAAGCCAGGTTGTGTTCGGCCCGGATCTGTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ACTGCTCTTCCCAAAGGCTTAGCCCCCAGGTAGCAGT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGCGAGCCCCTCAGTCCAGAGCCCATGCCTCCGGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CGAGCCGGCAGACGAACGGACACTGCGATATATGAAG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	ATCACACAGATTACCGAGTTTTTGCCTGAGTTCTTG
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGCTCACCTTGAGATTTCTGCCGCCCCTGAGTCCTA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AAAAACTATATGATGCACTATGCCGGGGCACTTCAA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGAAACCTGGCGTCAGGTTGTCATCGGCCCAAAGGG
GTTTCAATTCCTCATAGGTACGCTGAAAACC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018870.1\|WP_015051476.1\|2464856_2465594_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NC_018870.1\|WP_015051469.1\|2438070_2438394_+\|transposase	unknown	unknown	gnl\|CDD\|366690
NC_018870.1\|WP_015051478.1\|2465873_2466866_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_018870.1\|WP_015051485.1\|2473259_2474513_-\|CRISPR-associated-DxTHG-motif-protein	csx1	pfam09455_csx1_CAS-III	gnl\|CDD\|378186
NC_018870.1\|WP_015051484.1\|2471695_2473132_-\|CRISPR-associated-protein	cas8b1	pfam09484_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_018870.1\|WP_081578676.1\|2458292_2459963_+\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_018870.1\|WP_037999166.1\|2470356_2471271_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_018870.1\|WP_015051471.1\|2440644_2441883_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376773
NC_018870.1\|WP_037999167.1\|2466877_2467384_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_018870.1\|WP_015051472.1\|2448405_2449620_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018870.1\|WP_015051480.1\|2467373_2469641_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_018870.1\|WP_081578676.1\|2446079_2447750_-\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_018870.1\|WP_015051477.1\|2465607_2465871_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_018870.1\|WP_015051468.1\|2437832_2438030_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275209
NC_018870.1\|WP_148276019.1\|2469627_2470320_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_018870.1\|WP_015051475.1\|2452788_2453145_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NC_018870.1\|WP_015049782.1\|2453138_2453459_-\|IS66-family-insertion-sequence-hypothetical-protein	unknown	unknown	gnl\|CDD\|225511
NC_018870.1\|WP_015051483.1\|2471273_2471699_-\|CRISPR-associated-protein	cas8b1	mkCas0119_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_018870.1\|WP_015051472.1\|2442275_2443490_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018870.1\|WP_015051470.1\|2438417_2439062_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|379098

Protein	Function_ID	Function_description	E-value
NC_018870.1\|WP_015051476.1\|2464856_2465594_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.60943e-42
NC_018870.1\|WP_015051469.1\|2438070_2438394_+\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	1.36302e-09
NC_018870.1\|WP_015051478.1\|2465873_2466866_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	8.78104e-171
NC_018870.1\|WP_015051485.1\|2473259_2474513_-\|CRISPR-associated-DxTHG-motif-protein	gnl\|CDD\|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	1.53614e-66
NC_018870.1\|WP_015051484.1\|2471695_2473132_-\|CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.3023e-20
NC_018870.1\|WP_081578676.1\|2458292_2459963_+\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.8014e-28
NC_018870.1\|WP_037999166.1\|2470356_2471271_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	8.44442e-77
NC_018870.1\|WP_015051471.1\|2440644_2441883_-\|IS110-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	5.273e-26
NC_018870.1\|WP_037999167.1\|2466877_2467384_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.89318e-70
NC_018870.1\|WP_015051472.1\|2448405_2449620_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.31767e-41
NC_018870.1\|WP_015051480.1\|2467373_2469641_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	3.72763e-54
NC_018870.1\|WP_081578676.1\|2446079_2447750_-\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.8014e-28
NC_018870.1\|WP_015051477.1\|2465607_2465871_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.43479e-28
NC_018870.1\|WP_015051468.1\|2437832_2438030_+\|hypothetical-protein	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	4.96046e-15
NC_018870.1\|WP_148276019.1\|2469627_2470320_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	4.95478e-37
NC_018870.1\|WP_015051475.1\|2452788_2453145_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	1.30076e-55
NC_018870.1\|WP_015049782.1\|2453138_2453459_-\|IS66-family-insertion-sequence-hypothetical-protein	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.000769281
NC_018870.1\|WP_015051483.1\|2471273_2471699_-\|CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	7.70598e-09
NC_018870.1\|WP_015051472.1\|2442275_2443490_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.31767e-41
NC_018870.1\|WP_015051470.1\|2438417_2439062_+\|IS3-family-transposase	gnl\|CDD\|379098	pfam13276, HTH_21, HTH-like domain. This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.	7.64926e-08

>NC_018870.1|WP_081578676.1|2458292_2459963_+|IS1634-family-transposase
MWYNVDMYIRTIQRKNKDGSVVRYIQLAHNQWDPQARCAKAKVLFNFGREEEVDREALKRLVKSINRFLGPGETLRYEAETGAAPLKFITSRPLGGAWVLDRLWEELGIKGVLETLLKKRQYKTPVERAIFAMAANRALDPMSKRGVEEWVKEDAVIPGVEEIPLQQLYRAMDFLLENEAELQKQVYYSVANLLNLEVDILYFDTTSTYFEIEDEDEDGGLRRRGHSKDHRPDLPQAVIGLAVTRDGIPVRCWVWPGNTADISVVEQVKKDLIGWKLGRVITVLDRGFNSEDNLRCLQRAGGHYIAGEKLRSGKENTVQALKRGGRYQTVRDNLEVKEIVVGNGEARERYILVRNPEEAARDKARREKIIKELEEQLPHIKTHAKAVCELMAHPVYGRYLKLDSRSLPKIDRAKIREEEKLDGKYLLRTSDDTLSAEDVALGYKQLLLVEDAFRTLKSRLELRPVYHRLEDRIRSHVLLCWLALLLIRIAENRTGQTWCSLRATLQRMQLGEFSGTAGQVRQRTETTPAQKQIFKALAVKEPPLLFSINPTAKKNA
>NC_018870.1|WP_015049782.1|2453138_2453459_-|IS66-family-insertion-sequence-hypothetical-protein
MTRAELQKLWEARIAEYRESGQSVKEWCASHEGINPRQLWYWLRKFKNQTPAPPEISNRWLSVEISEEDSLEQALLVKIGPASIEVRPGFDPALLTKVVQVLMALC
>NC_018870.1|WP_015051475.1|2452788_2453145_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MLNEAGIDRVYLACGATDLRKSIDGLAVLVKEGFELDPFSSCLFVFCNRKRDKLKILHWEHNGFWLYYRRLEKGKFIWPQDTTSSTITISRRELRWLLDGLPLKQPKAHPEVKARTIL
>NC_018870.1|WP_015051472.1|2448405_2449620_+|IS110-family-transposase
MDVVFPYCCGLDVHKNSVVACVITPDEKEIRTFGTMTRDLLNLADWLTSKGCTHVAMESTGVYWKPIYNILEQYQLELLVVNAKHIKAVPGRKTDVKDAEWIADLLRHGLLKGSYIPDREQRELRELVGYRKSLVEERAREVNRIQKTLEGAGIKLSSVATDVVGVSGRAMIEGIISGIDDPAVLADFAQKKLKKKKEQLEQALFGLVGKHQRLLLAAQLRHIDYLDQEIARLDQQIEERMRPFEAELALLDTIPGVGRRTSQVILACIGADMSRFPSAAHLSSWAGVAPGNNESAGKRKSGKTTKGNTLLHTTLIQAARAASRTKNTYLSALYHRVAARRGANRAAVAVAHSILVSVYYMLIRRVPYHDLGGDYFEKRNSKAVVNRAVKQLEQLGYRVSIEVA
>NC_018870.1|WP_081578676.1|2446079_2447750_-|IS1634-family-transposase
MWYNVDMYIRTIQRKNKDGSVVRYIQLAHNQWDPQARCAKAKVLFNFGREEEVDREALKRLVKSINRFLGPGETLRYEAETGAAPLKFITSRPLGGAWVLDRLWEELGIKGVLETLLKKRQYKTPVERAIFAMAANRALDPMSKRGVEEWVKEDAVIPGVEEIPLQQLYRAMDFLLENEAELQKQVYYSVANLLNLEVDILYFDTTSTYFEIEDEDEDGGLRRRGHSKDHRPDLPQAVIGLAVTRDGIPVRCWVWPGNTADISVVEQVKKDLIGWKLGRVITVLDRGFNSEDNLRCLQRAGGHYIAGEKLRSGKENTVQALKRGGRYQTVRDNLEVKEIVVGNGEARERYILVRNPEEAARDKARREKIIKELEEQLPHIKTHAKAVCELMAHPVYGRYLKLDSRSLPKIDRAKIREEEKLDGKYLLRTSDDTLSAEDVALGYKQLLLVEDAFRTLKSRLELRPVYHRLEDRIRSHVLLCWLALLLIRIAENRTGQTWCSLRATLQRMQLGEFSGTAGQVRQRTETTPAQKQIFKALAVKEPPLLFSINPTAKKNA
>NC_018870.1|WP_015051472.1|2442275_2443490_+|IS110-family-transposase
MDVVFPYCCGLDVHKNSVVACVITPDEKEIRTFGTMTRDLLNLADWLTSKGCTHVAMESTGVYWKPIYNILEQYQLELLVVNAKHIKAVPGRKTDVKDAEWIADLLRHGLLKGSYIPDREQRELRELVGYRKSLVEERAREVNRIQKTLEGAGIKLSSVATDVVGVSGRAMIEGIISGIDDPAVLADFAQKKLKKKKEQLEQALFGLVGKHQRLLLAAQLRHIDYLDQEIARLDQQIEERMRPFEAELALLDTIPGVGRRTSQVILACIGADMSRFPSAAHLSSWAGVAPGNNESAGKRKSGKTTKGNTLLHTTLIQAARAASRTKNTYLSALYHRVAARRGANRAAVAVAHSILVSVYYMLIRRVPYHDLGGDYFEKRNSKAVVNRAVKQLEQLGYRVSIEVA
>NC_018870.1|WP_015051471.1|2440644_2441883_-|IS110-family-transposase
MKLFVGIDVSMKDFKARMFDAEGEEIAKRMRYKNDDPGAESFVKYLVEICGANEVDSLRIGMESTSVYGWHLQMRLAGEPLLASFHPQVYVFNPKVIANFRKQYVDIPKDDWFDCLVIADRLRFGRLPESCQVDFRYLPLQRLTRFRYHLIQTITREKNYFLTNLFLKFNTICQDKVLSDIFGATSEAILTEFLSPEEIAARPLDELIDFLMEKGKSHFSNPEATAKALKHAAACAYRLHGSLLEPVNLILATSLQTICTLEQQVKSIDRAIEKELSHFPNTLQSMPGMGPVCTAGIIAEIGDIHRFDNEKAVAKFAGLTWRKHQSGEFEADDTPLTKTGNVYLRYYFVMAADSVRKWDPRFAEFYARKFKESSTHHHRRALVLTARKLVRVVDALLRSNQLYVPQGQRKVV
>NC_018870.1|WP_015051470.1|2438417_2439062_+|IS3-family-transposase
MGYKVSLVLRIIGISRSTYYPNLKRQPKPRIFAGGRPKSHYTFTSDNKVVSNEQVKEWLCELITAEGFAYGYLKLTHCLRRKFHLIINKKKVYRLCKELDILRPQRKIKRKHPRRLARNRVITASNQLWEADLKYGYIAGEDRFFFIMPIIDVFDRCIVAYHIGLSCEAKDARVMSLPAMPKRMQRLSTSSTFTTKPGFIQQLNTYHRWNAINC
>NC_018870.1|WP_015051469.1|2438070_2438394_+|transposase
MNRKQYSPEMKMQIVKETLETGNASIVARRHDIAPSLVARWARCYKRYGTFYPQKEVPGTNGSCIPPDYKKITKENEQLKKLLGEKDLEIAILRDLLKKTNLPFPIK
>NC_018870.1|WP_015051468.1|2437832_2438030_+|hypothetical-protein
MEKVLERSNMLRALRRVKSNKGADGVDGMEIKSLRPYLKEHWPKIKEELLKGTYKLFSPLTRLNS
>NC_018870.1|WP_015051476.1|2464856_2465594_-|CRISPR-associated-endoribonuclease-Cas6
MRLIVEFRATENERITLPLQYNKAVQGMIYQRVREHLPELHDRGFVSAGRVFRLFVFSRIEGSGVKIINGMISFNSPVRIKIGSPNNNFLECLANSLLRTPQIDIGGSPLVVESVAIARNPDFSSGRVKVRAISPITVYSTLMSADGRKKTYYYHPEEKEFSDQIRNNIIKKGALLGVDDKEAYFTIEPYRVRNTDLKTVYYKDYVVKGWLGQYLLRGTPELLNIAYDAGIGAKNSQGFGMVEII
>NC_018870.1|WP_015051477.1|2465607_2465871_-|CRISPR-associated-endonuclease-Cas2
MFVIEVYDVNEKRVAKVLKVSRKYLYWVQNSVLEGEISEANFRRLKEELLEIIDLKEDSLIFYTFRTTKYSERQCFGVLKGGEETIF
>NC_018870.1|WP_015051478.1|2465873_2466866_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MRKSIYLLNSGELRRENNTICLITDEGKRFLPVEDIGEIHVFGEVDLNKRLLEFLSEKEIILHYYNHYDYYMGSFYPREHFNSGYMTVKQAEHYINPELRICLARAFVTGAVKNIRQVLMYYRNRGKEVGSAFERIEKLMGEIDSASSVDELMAYEGNIRDAYYGTFDLIIDNPDYVFEVRSKRPPKNRLNALISFGNTLLYTTTLSEIYRTHLDPRIGYLHTSNFRRFSLNLDVAEIFKPILVDRLIFYLTGKQMLKKSHFEKKLDGVVLSRSGRTLFIQNFEQRMMSTIKHRELGRQVSYRRLIRMELYKLEKHLMGEADYQPFVARW
>NC_018870.1|WP_037999167.1|2466877_2467384_-|CRISPR-associated-protein-Cas4
MIGEHWPVNGTLVWYYTICHRQVWLMARQLTPDEDDDNVAIGRFIHEHSYRRDRHELAVGNIRIDLMQASRDEVLIAEIKKSSRFLESARLQLKYYLFVLKSLGLDFKGVLLVPEERKRELVTLEEEDLVEIERIIGEIRRIIDSPVPPPAVRTRWCRPCAYAEFCWA
>NC_018870.1|WP_015051480.1|2467373_2469641_-|CRISPR-associated-helicase/endonuclease-Cas3
MSPGEVYSHKGKRLEQHLLETAELAQKIARHFRLELEEGERWALLLHDLAKAHPLFQKHLLQQKGRFGHAAPSAALVLGLTGDLLCTEAVRRHHSSLENLDEAKKFWFCWDYQENACGVIGKIPVWNGAEAVMEALGHQLAKWGELLPAQADWDELIFERVEFFPPDEEKMEEAWLRLRMLYSLLVTADRYNAAVGREMEYHPLRIDQKRVEDFAASLRGRPLAEWRQQVREEVVRKAEEVLKKPGIYTLTLPTGAGKTLVGLELAMLAAERFAATGIIYVLPFISLVEQNADVARVLFKDASPVREDHYLSEVAGEEGDPENSSPQERFLSFFRYWQEPVVITTMAKFWEVLYSPKGNDTMSLHRLSRAVVILDEPQAIPSCYWQGFGKTLNLLSEKLNTTFILMTATQPEIAQGLELAPRPYFFPMIRHRFEWRRERLTVPELLGSPDVISKLLAKSALLVFNTHRSALLAYLELQSRGVTSYFLSGWVTPLDRRATLQQIREDESAGKPARLVSTQVVEAGVDLDFQFVYRDLGPLDSIIQVAGRCNRHGKREQGEVLVCELCDENGRSYAGYVYDSTLLVATKAVLKDSFDERDCPGMVAAYYRKVREITAENPLWEDISSGRWGEFHDLIEKEERGEATLVVAYEGVENDLDLLSRQAAPDEDVMRMVEQKREASRRLGLHAVSVPVKMLEEWLLRVGGMIYGAESGDILRKVSSGIYLVQGEGIGRIYSRRTGFMPPDLEAAGDGVDDW
>NC_018870.1|WP_148276019.1|2469627_2470320_-|type-I-B-CRISPR-associated-protein-Cas5
MAMFRKPYTTTSMVSFPFPPPTAVCGLIAAIVGLDHGASEGALKAEYWDRVRGMQVALGLRRPVAWFSTAVNLIKFKSPSGDMGEHIQVKHQLLKRPAYRIYVRGGEVYDELKKRLERQEFIFTPYLGVAFALAEYSYVGEFRETPVEEEAMGIDSVLPLYGDVRLDLQQSGCLHSEVVPFRLDGIRRQQETVNVIYPEYRVNSRIYLRNRGDVEVSLVGTERVAWFEPW
>NC_018870.1|WP_037999166.1|2470356_2471271_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MEFKRRREFVFLYTVVDANPNGDPLNENHPRYDEDTLQALVSDVRIKRTVRDEWVNQERLVFVDGKPKTLKTRFEELKQSTGKEKGDEVLRECIDTRLFGVTFALGNESFAWTGPVQFKWGRSLHACTFEFIQGTSAFATEGGEGKEKQQRSFRNEYKVPFALIATYGIANQHAAKYTGATEEDLDLLAEALWSGTDNLITRSKQEHKSRFYLEITYKEGFNGKIGALDEKLRLLTAEGEEPDRDAQRALRRLSQLVVDIEPLIDAVEEKSDQIDRVRAIVNKELSLLGIDRLKNLAGAVIEVR
>NC_018870.1|WP_015051483.1|2471273_2471699_-|CRISPR-associated-protein
MKLDFLSDFEDPYLQSERGKGVFLAGVLLGYMARCQVGKEGDIKKAPLFKQIDFGRMDLKRLKRQLARVPQLISAYEGMQKHSYLINRLAAEVGRLILSGNGDLGIDGNFAFTVGFGNAASYFWKIFGKEGKEELDNEGGN
>NC_018870.1|WP_015051484.1|2471695_2473132_-|CRISPR-associated-protein
MGFISAIRSLGSLTPGKGLDPYLIFPMEKGGRLIRVALKVADREAEQIDVLGVAWVDLADQIMQPEMKGKYLYRKRAGSAATWGFSPIHLMGKPKKDSNKNREAIFGKGDNWAQDKGCHLNKIRNKLLLDYEREETFSPGSVDRVMAELPEKLKGILPHLDPKSSHAFIFGLEGDDGSFLYPGEVPAFLGYFRRKLEDTLKLGEEQVRCAYCRKLCTPRSLSKVFKFSTRDKVNICHGLDKKQEPWDFPVCDDCFESISSGRDRLQMKLNNNTVLPGINIWTLPEAVGGGGGRTLKQLIASVEEGLSQDRLQSPGEKRESRYFSRLAQEGSGLVFHFIFWERNNAQELVHLMVEDVPPERLAMLERKWGEAIKAVFGDVGRDDLFTLDWAIKSLYKTLSGFAGKSEGDKKVFRDYALKVIGKMLRGERLPVAFFKQAVVERAARLAFESGSWNDVARTLLYAQAWADYMYRINQEVAV
>NC_018870.1|WP_015051485.1|2473259_2474513_-|CRISPR-associated-DxTHG-motif-protein
MFVVLSTIGIGKYEEIEYCWLHGGGGYQIYRTALFPLAADAFFRPDKLLLMVTPEAHVHEHYREIERLLGNRLQPVPIPLGRTEDELWEIFDIVSGAVPDGARVVLDVTHALRSLPFVIFGVINYLRQTRDIHLERIIYGAYDAREAGPDGGWRAPVFDLTMLVDLHEWLQAVEAFIVRSEGEKLADLLMEAHRRQWISERREGEELPRQLQKMAGCIKVFSRSVRLLRPLEALSAAAKAQILGREVEREAARWAKPFGHILARLTDELTPLSAADTQMLDEGGLRCQLFLIKYFLEKDLIVQAVLMEREWLVNWLAWRAGFGDQWLNLKVRKKLESAMGVAVQKLKREKPTEESLPSWYSHLTEVDEITELWDHLTALRNDVAHCAMNDSPASPESISNRAKEMVQKLEQMLSTVS

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Crispr_ID: NC_018870_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018870_12

2463742-2464503

TypeIII

Consensus_repeat	Method
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CRT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CRISPRCasFinder
GTTTCAATTCCTCATAGGTACGCTGAAAAC	PILER-CR

11 spacers

cas6,cas2,cas1,cas4,cas3,cas5,cas7,cas8b1,csx1

The CRISPR arrays of NC_018870_12

>merge|NC_018870|12|2463742-2464503|CRT,CRISPRCasFinder,PILER-CR
ATCTATTTTCAGGGCAGGTACGCTGAAAACGACTGGCAGAGATTCGGGATGTCGTGAGGCAGTATCGTTTCAATTCCTCATAGGTACGCTGAAAACCCTGCAACCTAACACAGTCACAGACTGCCCAAGCATGTTTCAATTCCTCATAGGTACGCTGAAAACTCTAGAGGGAGGTGTGTATTATTATACTTTTACGACATAGTTTCAATTCCTCATAGGTACGCTGAAAACGGCAAATGTGTTGAATTGGTTGATAGAGCAGTTTGCGTTTCAATTCCTCATAGGTACGCTGAAAACTTGAAGTGAAAACCCCAGGCGGTAAACTGTCAAAATATGTTTCAATTCCTCATAGGTACGCTGAAAACGTTCAAGCTCATCACCACACAATTGCCGTATATCTTGTTTCAATTCCTCATAGGTACGCTGAAAACTTTTCATTATCGAAAAAGCAGAGAGCGTTGAAGAGAGTTTCAATTCCTCATAGGTACGCTGAAAACTTCTCCATTCCTATTCCAGCCTTTCCATGTACTTACGTTTCAATTCCTCATAGGTACGCTGAAAACAACGAAGCCGCAAACTGCATCCGCATCCCCTACTCGCGTTTCAATTCCTCATAGGTACGCTGAAAACTGGAAAATTACGGAAGGAGGAACAAAGTATGTTCAGTTTCAATTCCTCATAGGTACGCTGAAAACGAGGGAGAATGCCGCATGGTCGGGTCGAGTTCCGCGGGTTTCAATTCCTCATAGGTACGCTGAAAAC

>NC_018870|12|11|2463742-2464503|CRT
ATCTATTTTCAGGGCAGGTACGCTGAAAAC	GACTGGCAGAGATTCGGGATGTCGTGAGGCAGTATC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCTGCAACCTAACACAGTCACAGACTGCCCAAGCAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCTAGAGGGAGGTGTGTATTATTATACTTTTACGACATA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGCAAATGTGTTGAATTGGTTGATAGAGCAGTTTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTGAAGTGAAAACCCCAGGCGGTAAACTGTCAAAATAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTTCAAGCTCATCACCACACAATTGCCGTATATCTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTTTCATTATCGAAAAAGCAGAGAGCGTTGAAGAGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTCTCCATTCCTATTCCAGCCTTTCCATGTACTTAC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AACGAAGCCGCAAACTGCATCCGCATCCCCTACTCGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGGAAAATTACGGAAGGAGGAACAAAGTATGTTCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAGGGAGAATGCCGCATGGTCGGGTCGAGTTCCGCGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC

>NC_018870|12|11|2463808-2464503|CRISPRCasFinder
GTTTCAATTCCTCATAGGTACGCTGAAAAC	CCTGCAACCTAACACAGTCACAGACTGCCCAAGCAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TCTAGAGGGAGGTGTGTATTATTATACTTTTACGACATA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGCAAATGTGTTGAATTGGTTGATAGAGCAGTTTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTGAAGTGAAAACCCCAGGCGGTAAACTGTCAAAATAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTTCAAGCTCATCACCACACAATTGCCGTATATCTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTTTCATTATCGAAAAAGCAGAGAGCGTTGAAGAGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTCTCCATTCCTATTCCAGCCTTTCCATGTACTTAC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AACGAAGCCGCAAACTGCATCCGCATCCCCTACTCGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGGAAAATTACGGAAGGAGGAACAAAGTATGTTCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAGGGAGAATGCCGCATGGTCGGGTCGAGTTCCGCGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC

>NC_018870|12|13|2463943-2464503|PILER-CR
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GGCAAATGTGTTGAATTGGTTGATAGAGCAGTTTGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTGAAGTGAAAACCCCAGGCGGTAAACTGTCAAAATAT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GTTCAAGCTCATCACCACACAATTGCCGTATATCTT
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTTTCATTATCGAAAAAGCAGAGAGCGTTGAAGAGA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TTCTCCATTCCTATTCCAGCCTTTCCATGTACTTAC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	AACGAAGCCGCAAACTGCATCCGCATCCCCTACTCGC
GTTTCAATTCCTCATAGGTACGCTGAAAAC	TGGAAAATTACGGAAGGAGGAACAAAGTATGTTCA
GTTTCAATTCCTCATAGGTACGCTGAAAAC	GAGGGAGAATGCCGCATGGTCGGGTCGAGTTCCGCGG
GTTTCAATTCCTCATAGGTACGCTGAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018870.1\|WP_015051476.1\|2464856_2465594_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NC_018870.1\|WP_015051469.1\|2438070_2438394_+\|transposase	unknown	unknown	gnl\|CDD\|366690
NC_018870.1\|WP_015051478.1\|2465873_2466866_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_018870.1\|WP_015051485.1\|2473259_2474513_-\|CRISPR-associated-DxTHG-motif-protein	csx1	pfam09455_csx1_CAS-III	gnl\|CDD\|378186
NC_018870.1\|WP_015051484.1\|2471695_2473132_-\|CRISPR-associated-protein	cas8b1	pfam09484_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_018870.1\|WP_081578676.1\|2458292_2459963_+\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_018870.1\|WP_037999166.1\|2470356_2471271_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_018870.1\|WP_015051471.1\|2440644_2441883_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376773
NC_018870.1\|WP_037999167.1\|2466877_2467384_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_018870.1\|WP_015051472.1\|2448405_2449620_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018870.1\|WP_015051480.1\|2467373_2469641_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_018870.1\|WP_081578676.1\|2446079_2447750_-\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_018870.1\|WP_015051477.1\|2465607_2465871_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_018870.1\|WP_015051468.1\|2437832_2438030_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275209
NC_018870.1\|WP_148276019.1\|2469627_2470320_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_018870.1\|WP_015051475.1\|2452788_2453145_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NC_018870.1\|WP_015049782.1\|2453138_2453459_-\|IS66-family-insertion-sequence-hypothetical-protein	unknown	unknown	gnl\|CDD\|225511
NC_018870.1\|WP_015051483.1\|2471273_2471699_-\|CRISPR-associated-protein	cas8b1	mkCas0119_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_018870.1\|WP_015051472.1\|2442275_2443490_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_018870.1\|WP_015051470.1\|2438417_2439062_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|379098

Protein	Function_ID	Function_description	E-value
NC_018870.1\|WP_015051476.1\|2464856_2465594_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.60943e-42
NC_018870.1\|WP_015051469.1\|2438070_2438394_+\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	1.36302e-09
NC_018870.1\|WP_015051478.1\|2465873_2466866_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	8.78104e-171
NC_018870.1\|WP_015051485.1\|2473259_2474513_-\|CRISPR-associated-DxTHG-motif-protein	gnl\|CDD\|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	1.53614e-66
NC_018870.1\|WP_015051484.1\|2471695_2473132_-\|CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.3023e-20
NC_018870.1\|WP_081578676.1\|2458292_2459963_+\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.8014e-28
NC_018870.1\|WP_037999166.1\|2470356_2471271_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	8.44442e-77
NC_018870.1\|WP_015051471.1\|2440644_2441883_-\|IS110-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	5.273e-26
NC_018870.1\|WP_037999167.1\|2466877_2467384_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.89318e-70
NC_018870.1\|WP_015051472.1\|2448405_2449620_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.31767e-41
NC_018870.1\|WP_015051480.1\|2467373_2469641_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	3.72763e-54
NC_018870.1\|WP_081578676.1\|2446079_2447750_-\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.8014e-28
NC_018870.1\|WP_015051477.1\|2465607_2465871_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.43479e-28
NC_018870.1\|WP_015051468.1\|2437832_2438030_+\|hypothetical-protein	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	4.96046e-15
NC_018870.1\|WP_148276019.1\|2469627_2470320_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	4.95478e-37
NC_018870.1\|WP_015051475.1\|2452788_2453145_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	1.30076e-55
NC_018870.1\|WP_015049782.1\|2453138_2453459_-\|IS66-family-insertion-sequence-hypothetical-protein	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.000769281
NC_018870.1\|WP_015051483.1\|2471273_2471699_-\|CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	7.70598e-09
NC_018870.1\|WP_015051472.1\|2442275_2443490_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.31767e-41
NC_018870.1\|WP_015051470.1\|2438417_2439062_+\|IS3-family-transposase	gnl\|CDD\|379098	pfam13276, HTH_21, HTH-like domain. This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.	7.64926e-08

>NC_018870.1|WP_081578676.1|2458292_2459963_+|IS1634-family-transposase
MWYNVDMYIRTIQRKNKDGSVVRYIQLAHNQWDPQARCAKAKVLFNFGREEEVDREALKRLVKSINRFLGPGETLRYEAETGAAPLKFITSRPLGGAWVLDRLWEELGIKGVLETLLKKRQYKTPVERAIFAMAANRALDPMSKRGVEEWVKEDAVIPGVEEIPLQQLYRAMDFLLENEAELQKQVYYSVANLLNLEVDILYFDTTSTYFEIEDEDEDGGLRRRGHSKDHRPDLPQAVIGLAVTRDGIPVRCWVWPGNTADISVVEQVKKDLIGWKLGRVITVLDRGFNSEDNLRCLQRAGGHYIAGEKLRSGKENTVQALKRGGRYQTVRDNLEVKEIVVGNGEARERYILVRNPEEAARDKARREKIIKELEEQLPHIKTHAKAVCELMAHPVYGRYLKLDSRSLPKIDRAKIREEEKLDGKYLLRTSDDTLSAEDVALGYKQLLLVEDAFRTLKSRLELRPVYHRLEDRIRSHVLLCWLALLLIRIAENRTGQTWCSLRATLQRMQLGEFSGTAGQVRQRTETTPAQKQIFKALAVKEPPLLFSINPTAKKNA
>NC_018870.1|WP_015049782.1|2453138_2453459_-|IS66-family-insertion-sequence-hypothetical-protein
MTRAELQKLWEARIAEYRESGQSVKEWCASHEGINPRQLWYWLRKFKNQTPAPPEISNRWLSVEISEEDSLEQALLVKIGPASIEVRPGFDPALLTKVVQVLMALC
>NC_018870.1|WP_015051475.1|2452788_2453145_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MLNEAGIDRVYLACGATDLRKSIDGLAVLVKEGFELDPFSSCLFVFCNRKRDKLKILHWEHNGFWLYYRRLEKGKFIWPQDTTSSTITISRRELRWLLDGLPLKQPKAHPEVKARTIL
>NC_018870.1|WP_015051472.1|2448405_2449620_+|IS110-family-transposase
MDVVFPYCCGLDVHKNSVVACVITPDEKEIRTFGTMTRDLLNLADWLTSKGCTHVAMESTGVYWKPIYNILEQYQLELLVVNAKHIKAVPGRKTDVKDAEWIADLLRHGLLKGSYIPDREQRELRELVGYRKSLVEERAREVNRIQKTLEGAGIKLSSVATDVVGVSGRAMIEGIISGIDDPAVLADFAQKKLKKKKEQLEQALFGLVGKHQRLLLAAQLRHIDYLDQEIARLDQQIEERMRPFEAELALLDTIPGVGRRTSQVILACIGADMSRFPSAAHLSSWAGVAPGNNESAGKRKSGKTTKGNTLLHTTLIQAARAASRTKNTYLSALYHRVAARRGANRAAVAVAHSILVSVYYMLIRRVPYHDLGGDYFEKRNSKAVVNRAVKQLEQLGYRVSIEVA
>NC_018870.1|WP_081578676.1|2446079_2447750_-|IS1634-family-transposase
MWYNVDMYIRTIQRKNKDGSVVRYIQLAHNQWDPQARCAKAKVLFNFGREEEVDREALKRLVKSINRFLGPGETLRYEAETGAAPLKFITSRPLGGAWVLDRLWEELGIKGVLETLLKKRQYKTPVERAIFAMAANRALDPMSKRGVEEWVKEDAVIPGVEEIPLQQLYRAMDFLLENEAELQKQVYYSVANLLNLEVDILYFDTTSTYFEIEDEDEDGGLRRRGHSKDHRPDLPQAVIGLAVTRDGIPVRCWVWPGNTADISVVEQVKKDLIGWKLGRVITVLDRGFNSEDNLRCLQRAGGHYIAGEKLRSGKENTVQALKRGGRYQTVRDNLEVKEIVVGNGEARERYILVRNPEEAARDKARREKIIKELEEQLPHIKTHAKAVCELMAHPVYGRYLKLDSRSLPKIDRAKIREEEKLDGKYLLRTSDDTLSAEDVALGYKQLLLVEDAFRTLKSRLELRPVYHRLEDRIRSHVLLCWLALLLIRIAENRTGQTWCSLRATLQRMQLGEFSGTAGQVRQRTETTPAQKQIFKALAVKEPPLLFSINPTAKKNA
>NC_018870.1|WP_015051472.1|2442275_2443490_+|IS110-family-transposase
MDVVFPYCCGLDVHKNSVVACVITPDEKEIRTFGTMTRDLLNLADWLTSKGCTHVAMESTGVYWKPIYNILEQYQLELLVVNAKHIKAVPGRKTDVKDAEWIADLLRHGLLKGSYIPDREQRELRELVGYRKSLVEERAREVNRIQKTLEGAGIKLSSVATDVVGVSGRAMIEGIISGIDDPAVLADFAQKKLKKKKEQLEQALFGLVGKHQRLLLAAQLRHIDYLDQEIARLDQQIEERMRPFEAELALLDTIPGVGRRTSQVILACIGADMSRFPSAAHLSSWAGVAPGNNESAGKRKSGKTTKGNTLLHTTLIQAARAASRTKNTYLSALYHRVAARRGANRAAVAVAHSILVSVYYMLIRRVPYHDLGGDYFEKRNSKAVVNRAVKQLEQLGYRVSIEVA
>NC_018870.1|WP_015051471.1|2440644_2441883_-|IS110-family-transposase
MKLFVGIDVSMKDFKARMFDAEGEEIAKRMRYKNDDPGAESFVKYLVEICGANEVDSLRIGMESTSVYGWHLQMRLAGEPLLASFHPQVYVFNPKVIANFRKQYVDIPKDDWFDCLVIADRLRFGRLPESCQVDFRYLPLQRLTRFRYHLIQTITREKNYFLTNLFLKFNTICQDKVLSDIFGATSEAILTEFLSPEEIAARPLDELIDFLMEKGKSHFSNPEATAKALKHAAACAYRLHGSLLEPVNLILATSLQTICTLEQQVKSIDRAIEKELSHFPNTLQSMPGMGPVCTAGIIAEIGDIHRFDNEKAVAKFAGLTWRKHQSGEFEADDTPLTKTGNVYLRYYFVMAADSVRKWDPRFAEFYARKFKESSTHHHRRALVLTARKLVRVVDALLRSNQLYVPQGQRKVV
>NC_018870.1|WP_015051470.1|2438417_2439062_+|IS3-family-transposase
MGYKVSLVLRIIGISRSTYYPNLKRQPKPRIFAGGRPKSHYTFTSDNKVVSNEQVKEWLCELITAEGFAYGYLKLTHCLRRKFHLIINKKKVYRLCKELDILRPQRKIKRKHPRRLARNRVITASNQLWEADLKYGYIAGEDRFFFIMPIIDVFDRCIVAYHIGLSCEAKDARVMSLPAMPKRMQRLSTSSTFTTKPGFIQQLNTYHRWNAINC
>NC_018870.1|WP_015051469.1|2438070_2438394_+|transposase
MNRKQYSPEMKMQIVKETLETGNASIVARRHDIAPSLVARWARCYKRYGTFYPQKEVPGTNGSCIPPDYKKITKENEQLKKLLGEKDLEIAILRDLLKKTNLPFPIK
>NC_018870.1|WP_015051468.1|2437832_2438030_+|hypothetical-protein
MEKVLERSNMLRALRRVKSNKGADGVDGMEIKSLRPYLKEHWPKIKEELLKGTYKLFSPLTRLNS
>NC_018870.1|WP_015051476.1|2464856_2465594_-|CRISPR-associated-endoribonuclease-Cas6
MRLIVEFRATENERITLPLQYNKAVQGMIYQRVREHLPELHDRGFVSAGRVFRLFVFSRIEGSGVKIINGMISFNSPVRIKIGSPNNNFLECLANSLLRTPQIDIGGSPLVVESVAIARNPDFSSGRVKVRAISPITVYSTLMSADGRKKTYYYHPEEKEFSDQIRNNIIKKGALLGVDDKEAYFTIEPYRVRNTDLKTVYYKDYVVKGWLGQYLLRGTPELLNIAYDAGIGAKNSQGFGMVEII
>NC_018870.1|WP_015051477.1|2465607_2465871_-|CRISPR-associated-endonuclease-Cas2
MFVIEVYDVNEKRVAKVLKVSRKYLYWVQNSVLEGEISEANFRRLKEELLEIIDLKEDSLIFYTFRTTKYSERQCFGVLKGGEETIF
>NC_018870.1|WP_015051478.1|2465873_2466866_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MRKSIYLLNSGELRRENNTICLITDEGKRFLPVEDIGEIHVFGEVDLNKRLLEFLSEKEIILHYYNHYDYYMGSFYPREHFNSGYMTVKQAEHYINPELRICLARAFVTGAVKNIRQVLMYYRNRGKEVGSAFERIEKLMGEIDSASSVDELMAYEGNIRDAYYGTFDLIIDNPDYVFEVRSKRPPKNRLNALISFGNTLLYTTTLSEIYRTHLDPRIGYLHTSNFRRFSLNLDVAEIFKPILVDRLIFYLTGKQMLKKSHFEKKLDGVVLSRSGRTLFIQNFEQRMMSTIKHRELGRQVSYRRLIRMELYKLEKHLMGEADYQPFVARW
>NC_018870.1|WP_037999167.1|2466877_2467384_-|CRISPR-associated-protein-Cas4
MIGEHWPVNGTLVWYYTICHRQVWLMARQLTPDEDDDNVAIGRFIHEHSYRRDRHELAVGNIRIDLMQASRDEVLIAEIKKSSRFLESARLQLKYYLFVLKSLGLDFKGVLLVPEERKRELVTLEEEDLVEIERIIGEIRRIIDSPVPPPAVRTRWCRPCAYAEFCWA
>NC_018870.1|WP_015051480.1|2467373_2469641_-|CRISPR-associated-helicase/endonuclease-Cas3
MSPGEVYSHKGKRLEQHLLETAELAQKIARHFRLELEEGERWALLLHDLAKAHPLFQKHLLQQKGRFGHAAPSAALVLGLTGDLLCTEAVRRHHSSLENLDEAKKFWFCWDYQENACGVIGKIPVWNGAEAVMEALGHQLAKWGELLPAQADWDELIFERVEFFPPDEEKMEEAWLRLRMLYSLLVTADRYNAAVGREMEYHPLRIDQKRVEDFAASLRGRPLAEWRQQVREEVVRKAEEVLKKPGIYTLTLPTGAGKTLVGLELAMLAAERFAATGIIYVLPFISLVEQNADVARVLFKDASPVREDHYLSEVAGEEGDPENSSPQERFLSFFRYWQEPVVITTMAKFWEVLYSPKGNDTMSLHRLSRAVVILDEPQAIPSCYWQGFGKTLNLLSEKLNTTFILMTATQPEIAQGLELAPRPYFFPMIRHRFEWRRERLTVPELLGSPDVISKLLAKSALLVFNTHRSALLAYLELQSRGVTSYFLSGWVTPLDRRATLQQIREDESAGKPARLVSTQVVEAGVDLDFQFVYRDLGPLDSIIQVAGRCNRHGKREQGEVLVCELCDENGRSYAGYVYDSTLLVATKAVLKDSFDERDCPGMVAAYYRKVREITAENPLWEDISSGRWGEFHDLIEKEERGEATLVVAYEGVENDLDLLSRQAAPDEDVMRMVEQKREASRRLGLHAVSVPVKMLEEWLLRVGGMIYGAESGDILRKVSSGIYLVQGEGIGRIYSRRTGFMPPDLEAAGDGVDDW
>NC_018870.1|WP_148276019.1|2469627_2470320_-|type-I-B-CRISPR-associated-protein-Cas5
MAMFRKPYTTTSMVSFPFPPPTAVCGLIAAIVGLDHGASEGALKAEYWDRVRGMQVALGLRRPVAWFSTAVNLIKFKSPSGDMGEHIQVKHQLLKRPAYRIYVRGGEVYDELKKRLERQEFIFTPYLGVAFALAEYSYVGEFRETPVEEEAMGIDSVLPLYGDVRLDLQQSGCLHSEVVPFRLDGIRRQQETVNVIYPEYRVNSRIYLRNRGDVEVSLVGTERVAWFEPW
>NC_018870.1|WP_037999166.1|2470356_2471271_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MEFKRRREFVFLYTVVDANPNGDPLNENHPRYDEDTLQALVSDVRIKRTVRDEWVNQERLVFVDGKPKTLKTRFEELKQSTGKEKGDEVLRECIDTRLFGVTFALGNESFAWTGPVQFKWGRSLHACTFEFIQGTSAFATEGGEGKEKQQRSFRNEYKVPFALIATYGIANQHAAKYTGATEEDLDLLAEALWSGTDNLITRSKQEHKSRFYLEITYKEGFNGKIGALDEKLRLLTAEGEEPDRDAQRALRRLSQLVVDIEPLIDAVEEKSDQIDRVRAIVNKELSLLGIDRLKNLAGAVIEVR
>NC_018870.1|WP_015051483.1|2471273_2471699_-|CRISPR-associated-protein
MKLDFLSDFEDPYLQSERGKGVFLAGVLLGYMARCQVGKEGDIKKAPLFKQIDFGRMDLKRLKRQLARVPQLISAYEGMQKHSYLINRLAAEVGRLILSGNGDLGIDGNFAFTVGFGNAASYFWKIFGKEGKEELDNEGGN
>NC_018870.1|WP_015051484.1|2471695_2473132_-|CRISPR-associated-protein
MGFISAIRSLGSLTPGKGLDPYLIFPMEKGGRLIRVALKVADREAEQIDVLGVAWVDLADQIMQPEMKGKYLYRKRAGSAATWGFSPIHLMGKPKKDSNKNREAIFGKGDNWAQDKGCHLNKIRNKLLLDYEREETFSPGSVDRVMAELPEKLKGILPHLDPKSSHAFIFGLEGDDGSFLYPGEVPAFLGYFRRKLEDTLKLGEEQVRCAYCRKLCTPRSLSKVFKFSTRDKVNICHGLDKKQEPWDFPVCDDCFESISSGRDRLQMKLNNNTVLPGINIWTLPEAVGGGGGRTLKQLIASVEEGLSQDRLQSPGEKRESRYFSRLAQEGSGLVFHFIFWERNNAQELVHLMVEDVPPERLAMLERKWGEAIKAVFGDVGRDDLFTLDWAIKSLYKTLSGFAGKSEGDKKVFRDYALKVIGKMLRGERLPVAFFKQAVVERAARLAFESGSWNDVARTLLYAQAWADYMYRINQEVAV
>NC_018870.1|WP_015051485.1|2473259_2474513_-|CRISPR-associated-DxTHG-motif-protein
MFVVLSTIGIGKYEEIEYCWLHGGGGYQIYRTALFPLAADAFFRPDKLLLMVTPEAHVHEHYREIERLLGNRLQPVPIPLGRTEDELWEIFDIVSGAVPDGARVVLDVTHALRSLPFVIFGVINYLRQTRDIHLERIIYGAYDAREAGPDGGWRAPVFDLTMLVDLHEWLQAVEAFIVRSEGEKLADLLMEAHRRQWISERREGEELPRQLQKMAGCIKVFSRSVRLLRPLEALSAAAKAQILGREVEREAARWAKPFGHILARLTDELTPLSAADTQMLDEGGLRCQLFLIKYFLEKDLIVQAVLMEREWLVNWLAWRAGFGDQWLNLKVRKKLESAMGVAVQKLKREKPTEESLPSWYSHLTEVDEITELWDHLTALRNDVAHCAMNDSPASPESISNRAKEMVQKLEQMLSTVS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	438158-438193	5	0.861
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	1895171-1895206	5	0.861
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	438164-438199	6	0.833
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	KT381879	Caulobacter phage Percy, complete genome	23890-23925	6	0.833
NC_018870_4	4.55\|2208240\|35\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2208240-2208274	35	NZ_AP022338	Mameliella alba strain KU6B plasmid pKUB257, complete sequence	246349-246383	7	0.8
NC_018870_10	10.38\|2455728\|30\|NC_018870\|PILER-CR	2455728-2455757	30	MN693348	Marine virus AFVG_25M369, complete genome	10186-10215	7	0.767
NC_018870_11	11.19\|2461262\|36\|NC_018870\|CRT,PILER-CR,CRISPRCasFinder	2461262-2461297	36	JF712866	Vibrio phage phiVC8, complete genome	7902-7937	7	0.806
NC_018870_3	3.71\|1920311\|35\|NC_018870\|CRISPRCasFinder,CRT	1920311-1920345	35	NZ_CP010651	Phaeobacter inhibens strain P54 plasmid pP54_a, complete sequence	59166-59200	8	0.771
NC_018870_3	3.183\|1920312\|35\|NC_018870\|PILER-CR	1920312-1920346	35	NZ_CP010651	Phaeobacter inhibens strain P54 plasmid pP54_a, complete sequence	59166-59200	8	0.771
NC_018870_4	4.55\|2208240\|35\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2208240-2208274	35	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	80772-80806	8	0.771
NC_018870_5	5.1\|2439422\|31\|NC_018870\|PILER-CR	2439422-2439452	31	NZ_CP023738	Methylosinus trichosporium OB3b plasmid pOB3b1, complete sequence	79249-79279	8	0.742
NC_018870_5	5.1\|2439422\|31\|NC_018870\|PILER-CR	2439422-2439452	31	NZ_CP021041	Phaeobacter gallaeciensis strain P129 plasmid pP129_a, complete sequence	191475-191505	8	0.742
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	1521447-1521482	8	0.778
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	MN693799	Marine virus AFVG_250M1075, complete genome	14017-14052	8	0.778
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP034351	Streptomyces sp. W1SF4 plasmid p1, complete sequence	247847-247882	8	0.778
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	1273519-1273554	8	0.778
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NC_021347	Rhodococcus phage E3, complete genome	103692-103727	8	0.778
NC_018870_10	10.39\|2455796\|33\|NC_018870\|PILER-CR	2455796-2455828	33	NZ_CP030772	Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence	445886-445918	8	0.758
NC_018870_3	3.36\|1917729\|36\|NC_018870\|CRISPRCasFinder,CRT	1917729-1917764	36	NZ_CP032686	Rhizobium sp. CCGE531 plasmid pRCCGE531c, complete sequence	422854-422889	9	0.75
NC_018870_3	3.36\|1917729\|36\|NC_018870\|CRISPRCasFinder,CRT	1917729-1917764	36	NZ_CP032691	Rhizobium sp. CCGE532 plasmid pRCCGE532c, complete sequence	414171-414206	9	0.75
NC_018870_3	3.76\|1920679\|35\|NC_018870\|CRISPRCasFinder,CRT	1920679-1920713	35	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	636535-636569	9	0.743
NC_018870_3	3.76\|1920679\|35\|NC_018870\|CRISPRCasFinder,CRT	1920679-1920713	35	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	636553-636587	9	0.743
NC_018870_3	3.148\|1917730\|36\|NC_018870\|PILER-CR	1917730-1917765	36	NZ_CP032686	Rhizobium sp. CCGE531 plasmid pRCCGE531c, complete sequence	422854-422889	9	0.75
NC_018870_3	3.148\|1917730\|36\|NC_018870\|PILER-CR	1917730-1917765	36	NZ_CP032691	Rhizobium sp. CCGE532 plasmid pRCCGE532c, complete sequence	414171-414206	9	0.75
NC_018870_3	3.188\|1920680\|35\|NC_018870\|PILER-CR	1920680-1920714	35	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	636535-636569	9	0.743
NC_018870_3	3.188\|1920680\|35\|NC_018870\|PILER-CR	1920680-1920714	35	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	636553-636587	9	0.743
NC_018870_4	4.55\|2208240\|35\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2208240-2208274	35	NZ_CP021915	Sagittula sp. P11 plasmid unnamed2, complete sequence	2859-2893	9	0.743
NC_018870_7	7.2\|2447976\|32\|NC_018870\|CRT	2447976-2448007	32	NZ_CP053316	Bacillus circulans strain GN03 plasmid unnamed, complete sequence	129188-129219	9	0.719
NC_018870_8	8.12\|2450465\|35\|NC_018870\|CRT,PILER-CR,CRISPRCasFinder	2450465-2450499	35	NC_011960	Rhodobacter sphaeroides KD131 plasmid pRSKD131B, complete sequence	43153-43187	9	0.743
NC_018870_8	8.12\|2450465\|35\|NC_018870\|CRT,PILER-CR,CRISPRCasFinder	2450465-2450499	35	NC_009040	Rhodobacter sphaeroides ATCC 17029 plasmid pRSPH01, complete sequence	48959-48993	9	0.743
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	570783-570818	9	0.75
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	570783-570818	9	0.75
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	1424369-1424404	9	0.75
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	1373348-1373383	9	0.75
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	1373370-1373405	9	0.75
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	1373370-1373405	9	0.75
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	1373370-1373405	9	0.75
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	1373370-1373405	9	0.75
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	1373370-1373405	9	0.75
NC_018870_3	3.53\|1918985\|35\|NC_018870\|CRISPRCasFinder,CRT	1918985-1919019	35	NZ_CP025552	Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence	267893-267927	10	0.714
NC_018870_3	3.165\|1918986\|35\|NC_018870\|PILER-CR	1918986-1919020	35	NZ_CP025552	Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence	267893-267927	10	0.714
NC_018870_4	4.55\|2208240\|35\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2208240-2208274	35	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1715740-1715774	10	0.714
NC_018870_5	5.2\|2439487\|32\|NC_018870\|PILER-CR	2439487-2439518	32	NC_019694	Oscillatoria acuminata PCC 6304 plasmid pOSCIL6304.02, complete sequence	8701-8732	10	0.688
NC_018870_7	7.4\|2447976\|33\|NC_018870\|PILER-CR	2447976-2448008	33	NZ_CP053316	Bacillus circulans strain GN03 plasmid unnamed, complete sequence	129187-129219	10	0.697
NC_018870_8	8.19\|2450927\|36\|NC_018870\|CRT,PILER-CR,CRISPRCasFinder	2450927-2450962	36	NZ_CP032695	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence	2414214-2414249	10	0.722
NC_018870_10	10.2\|2455774\|36\|NC_018870\|CRT,CRISPRCasFinder	2455774-2455809	36	NZ_CP030772	Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence	445884-445919	10	0.722
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	338510-338545	10	0.722
NC_018870_10	10.39\|2455796\|33\|NC_018870\|PILER-CR	2455796-2455828	33	NZ_CP023976	Streptomyces alboflavus strain MDJK44 plasmid pMDJK44.1, complete sequence	14239-14271	10	0.697
NC_018870_3	3.74\|1920531\|35\|NC_018870\|CRISPRCasFinder,CRT	1920531-1920565	35	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	291806-291840	11	0.686
NC_018870_3	3.74\|1920531\|35\|NC_018870\|CRISPRCasFinder,CRT	1920531-1920565	35	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	628539-628573	11	0.686
NC_018870_3	3.74\|1920531\|35\|NC_018870\|CRISPRCasFinder,CRT	1920531-1920565	35	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	100040-100074	11	0.686
NC_018870_3	3.76\|1920679\|35\|NC_018870\|CRISPRCasFinder,CRT	1920679-1920713	35	NC_019959	Mycobacterium sp. JS623 plasmid pMYCSM03, complete sequence	91709-91743	11	0.686
NC_018870_3	3.186\|1920532\|35\|NC_018870\|PILER-CR	1920532-1920566	35	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	291806-291840	11	0.686
NC_018870_3	3.186\|1920532\|35\|NC_018870\|PILER-CR	1920532-1920566	35	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	628539-628573	11	0.686
NC_018870_3	3.186\|1920532\|35\|NC_018870\|PILER-CR	1920532-1920566	35	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	100040-100074	11	0.686
NC_018870_3	3.188\|1920680\|35\|NC_018870\|PILER-CR	1920680-1920714	35	NC_019959	Mycobacterium sp. JS623 plasmid pMYCSM03, complete sequence	91709-91743	11	0.686
NC_018870_4	4.85\|2210227\|36\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2210227-2210262	36	MK448839	Streptococcus phage Javan102, complete genome	2850-2885	11	0.694
NC_018870_4	4.85\|2210227\|36\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2210227-2210262	36	MK448667	Streptococcus phage Javan105, complete genome	2850-2885	11	0.694
NC_018870_4	4.85\|2210227\|36\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2210227-2210262	36	MK448843	Streptococcus phage Javan112, complete genome	2850-2885	11	0.694
NC_018870_4	4.85\|2210227\|36\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2210227-2210262	36	MK448841	Streptococcus phage Javan108, complete genome	2850-2885	11	0.694
NC_018870_4	4.100\|2211218\|37\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2211218-2211254	37	LR877331	Klebsiella phage vB_KpnM_311F genome assembly, chromosome: 1	49844-49880	11	0.703
NC_018870_4	4.100\|2211218\|37\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2211218-2211254	37	MN101226	Klebsiella phage KPN2 HKu-2019, complete genome	54156-54192	11	0.703
NC_018870_4	4.100\|2211218\|37\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2211218-2211254	37	NC_031095	Klebsiella phage PKO111, complete genome	97972-98008	11	0.703
NC_018870_4	4.100\|2211218\|37\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2211218-2211254	37	MH333064	Klebsiella phage Mineola, complete genome	10733-10769	11	0.703
NC_018870_4	4.100\|2211218\|37\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2211218-2211254	37	MN434095	Klebsiella pneumoniae phage JIPh_Kp122, complete genome	244-280	11	0.703
NC_018870_4	4.100\|2211218\|37\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2211218-2211254	37	MN101230	Klebsiella phage KPN6, complete genome	82331-82367	11	0.703
NC_018870_4	4.100\|2211218\|37\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2211218-2211254	37	MN101229	Klebsiella phage KPN5, complete genome	75467-75503	11	0.703
NC_018870_4	4.100\|2211218\|37\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2211218-2211254	37	KY000080	Klebsiella phage KPV15, complete genome	20254-20290	11	0.703
NC_018870_4	4.100\|2211218\|37\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2211218-2211254	37	MG751100	Klebsiella phage KP1, complete genome	288-324	11	0.703
NC_018870_4	4.100\|2211218\|37\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2211218-2211254	37	NC_028686	Klebsiella phage JD18, complete genome	288-324	11	0.703
NC_018870_4	4.100\|2211218\|37\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2211218-2211254	37	MK421971	Klebsiella phage vB_KpnM_GF, partial genome	288-324	11	0.703
NC_018870_4	4.100\|2211218\|37\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2211218-2211254	37	NC_031087	Klebsiella phage vB_KpnM_KpV477, complete genome	10407-10443	11	0.703
NC_018870_4	4.100\|2211218\|37\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2211218-2211254	37	CP062992	Klebsiella phage AShe-2020a, complete genome	122482-122518	11	0.703
NC_018870_4	4.100\|2211218\|37\|NC_018870\|PILER-CR,CRISPRCasFinder,CRT	2211218-2211254	37	MH729874	Klebsiella phage KP179, complete genome	141902-141938	12	0.676
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	1521453-1521488	12	0.667
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	1273525-1273560	12	0.667
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	1459560-1459595	12	0.667
NC_018870_10	10.13\|2456501\|36\|NC_018870\|CRT,CRISPRCasFinder,PILER-CR	2456501-2456536	36	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	1459542-1459577	12	0.667

1. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.861

-gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
tgccg-ctgcggctgcggctgcggctgcggctgcggc	Protospacer
 **** **. ********************** * **

2. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 5, identity: 0.861

-gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
tgccg-ctgcggctgcggctgcggctgcggctgcggc	Protospacer
 **** **. ********************** * **

3. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.833

-gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
tgccg-ctgccgctgcggctgcggctgcggctgcggc	Protospacer
 **** **.  ********************* * **

4. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to KT381879 (Caulobacter phage Percy, complete genome) position: , mismatch: 6, identity: 0.833

---gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
ggacccgatt---gctgcggctgcggctgcggctgctgc	Protospacer
    ****.*   ********************* ****

5. spacer 4.55|2208240|35|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022338 (Mameliella alba strain KU6B plasmid pKUB257, complete sequence) position: , mismatch: 7, identity: 0.8

ttcaacctcgcgccgcgccttctcctgcgcggcct	CRISPR spacer
ctcaacctcgcgccgcgcgttctgctgcccaagct	Protospacer
.***************** **** **** *.. **

6. spacer 10.38|2455728|30|NC_018870|PILER-CR matches to MN693348 (Marine virus AFVG_25M369, complete genome) position: , mismatch: 7, identity: 0.767

ggtgtgtgattgtatgaaagatgacgatga	CRISPR spacer
tcattatgattgtatgaaaaaagacgatga	Protospacer
    *.*************.* ********

7. spacer 11.19|2461262|36|NC_018870|CRT,PILER-CR,CRISPRCasFinder matches to JF712866 (Vibrio phage phiVC8, complete genome) position: , mismatch: 7, identity: 0.806

caaagaagaactgaccaagatggtggctgatgcggt-	CRISPR spacer
acaagacgaactcaccaagatggtggct-acgcagta	Protospacer
  **** ***** *************** *.**.**

8. spacer 3.71|1920311|35|NC_018870|CRISPRCasFinder,CRT matches to NZ_CP010651 (Phaeobacter inhibens strain P54 plasmid pP54_a, complete sequence) position: , mismatch: 8, identity: 0.771

tccttcacccaggtcatgctatccacgctatacca-	CRISPR spacer
cccttccgccaggtcatgctatccac-cggcaccga	Protospacer
.*****  ****************** * ..***.

9. spacer 3.183|1920312|35|NC_018870|PILER-CR matches to NZ_CP010651 (Phaeobacter inhibens strain P54 plasmid pP54_a, complete sequence) position: , mismatch: 8, identity: 0.771

tccttcacccaggtcatgctatccacgctatacca-	CRISPR spacer
cccttccgccaggtcatgctatccac-cggcaccga	Protospacer
.*****  ****************** * ..***.

10. spacer 4.55|2208240|35|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 8, identity: 0.771

ttcaacctcgcgccgcgccttctcctgcgcggcct	CRISPR spacer
gtcaacctcgcgccccgccttttcctgcttgacga	Protospacer
 ************* ******.****** .*.*

11. spacer 5.1|2439422|31|NC_018870|PILER-CR matches to NZ_CP023738 (Methylosinus trichosporium OB3b plasmid pOB3b1, complete sequence) position: , mismatch: 8, identity: 0.742

gcattggctttcatctccccctcggcatgcc	CRISPR spacer
acggcgcctttcatctcgccctcgccatgca	Protospacer
.*. .* ********** ****** *****

12. spacer 5.1|2439422|31|NC_018870|PILER-CR matches to NZ_CP021041 (Phaeobacter gallaeciensis strain P129 plasmid pP129_a, complete sequence) position: , mismatch: 8, identity: 0.742

gcattggctttcatctccccctcggcatgcc	CRISPR spacer
gcattggctttcagctccacctctatttcca	Protospacer
************* **** **** .. * *

13. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 8, identity: 0.778

gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
tttggctgcggctgcggctgcggctgcggctgcggc	Protospacer
 ..*.**. ********************** * **

14. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to MN693799 (Marine virus AFVG_250M1075, complete genome) position: , mismatch: 8, identity: 0.778

gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
tgtggctgcggctgcggctgcggctgcggctgcggc	Protospacer
  .*.**. ********************** * **

15. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP034351 (Streptomyces sp. W1SF4 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.778

gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
cgggtctccggctgcggctgcggctgcgggtcctga	Protospacer
   * **  ******************** *****

16. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 8, identity: 0.778

gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
tttggctgcggctgcggctgcggctgcggctgcggc	Protospacer
 ..*.**. ********************** * **

17. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NC_021347 (Rhodococcus phage E3, complete genome) position: , mismatch: 8, identity: 0.778

gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
ggctgctgctgctgcggctgctgctgcggctgctgc	Protospacer
* * .**.  *********** ********* ****

18. spacer 10.39|2455796|33|NC_018870|PILER-CR matches to NZ_CP030772 (Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence) position: , mismatch: 8, identity: 0.758

tgtgccggaggtgtgcccgaactgcgcagatat	CRISPR spacer
ggtgccggtggtgtgcccggactgcgcaacgcc	Protospacer
 ******* **********.********.   .

19. spacer 3.36|1917729|36|NC_018870|CRISPRCasFinder,CRT matches to NZ_CP032686 (Rhizobium sp. CCGE531 plasmid pRCCGE531c, complete sequence) position: , mismatch: 9, identity: 0.75

agaaacgtccgcagtgagtcctgtcggcgcaggaac	CRISPR spacer
gcgttcgtccgcagtgagacctgtgggcgcaggggc	Protospacer
. .  ************* ***** ********..*

20. spacer 3.36|1917729|36|NC_018870|CRISPRCasFinder,CRT matches to NZ_CP032691 (Rhizobium sp. CCGE532 plasmid pRCCGE532c, complete sequence) position: , mismatch: 9, identity: 0.75

agaaacgtccgcagtgagtcctgtcggcgcaggaac	CRISPR spacer
gcgttcgtccgcagtgagacctgtgggcgcaggggc	Protospacer
. .  ************* ***** ********..*

21. spacer 3.76|1920679|35|NC_018870|CRISPRCasFinder,CRT matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.743

acctccgggtggatgccgccggcgccgacctgacc	CRISPR spacer
gccgccgggtggatgctgccggcgcccatccacgc	Protospacer
.** ************.********* *.*..  *

22. spacer 3.76|1920679|35|NC_018870|CRISPRCasFinder,CRT matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.743

acctccgggtggatgccgccggcgccgacctgacc	CRISPR spacer
gccgccgggtggatgctgccggcgcccatccacgc	Protospacer
.** ************.********* *.*..  *

23. spacer 3.148|1917730|36|NC_018870|PILER-CR matches to NZ_CP032686 (Rhizobium sp. CCGE531 plasmid pRCCGE531c, complete sequence) position: , mismatch: 9, identity: 0.75

agaaacgtccgcagtgagtcctgtcggcgcaggaac	CRISPR spacer
gcgttcgtccgcagtgagacctgtgggcgcaggggc	Protospacer
. .  ************* ***** ********..*

24. spacer 3.148|1917730|36|NC_018870|PILER-CR matches to NZ_CP032691 (Rhizobium sp. CCGE532 plasmid pRCCGE532c, complete sequence) position: , mismatch: 9, identity: 0.75

agaaacgtccgcagtgagtcctgtcggcgcaggaac	CRISPR spacer
gcgttcgtccgcagtgagacctgtgggcgcaggggc	Protospacer
. .  ************* ***** ********..*

25. spacer 3.188|1920680|35|NC_018870|PILER-CR matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.743

acctccgggtggatgccgccggcgccgacctgacc	CRISPR spacer
gccgccgggtggatgctgccggcgcccatccacgc	Protospacer
.** ************.********* *.*..  *

26. spacer 3.188|1920680|35|NC_018870|PILER-CR matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.743

acctccgggtggatgccgccggcgccgacctgacc	CRISPR spacer
gccgccgggtggatgctgccggcgcccatccacgc	Protospacer
.** ************.********* *.*..  *

27. spacer 4.55|2208240|35|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021915 (Sagittula sp. P11 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.743

ttcaacctcgcgccgcgccttctcctgcgcggcct	CRISPR spacer
cttcagggcgcgccgcgctttctcctgcgccgctt	Protospacer
.*. *   **********.*********** **.*

28. spacer 7.2|2447976|32|NC_018870|CRT matches to NZ_CP053316 (Bacillus circulans strain GN03 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

gatattgttcaaactttgcattcatttcgttc	CRISPR spacer
cgaattgctcaaactttgcattcactttaccc	Protospacer
 . ****.****************.**....*

29. spacer 8.12|2450465|35|NC_018870|CRT,PILER-CR,CRISPRCasFinder matches to NC_011960 (Rhodobacter sphaeroides KD131 plasmid pRSKD131B, complete sequence) position: , mismatch: 9, identity: 0.743

tccccggccggccggtgcctgccgcaaggatgacg-----	CRISPR spacer
accccggccgaccggtgcgtgccgca-----gccgatcgg	Protospacer
 *********.******* *******     * **

30. spacer 8.12|2450465|35|NC_018870|CRT,PILER-CR,CRISPRCasFinder matches to NC_009040 (Rhodobacter sphaeroides ATCC 17029 plasmid pRSPH01, complete sequence) position: , mismatch: 9, identity: 0.743

tccccggccggccggtgcctgccgcaaggatgacg-----	CRISPR spacer
accccggccgaccggtgcgtgccgca-----gccgatcgg	Protospacer
 *********.******* *******     * **

31. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
tttgactgcggctgcggctgcggctgcggctgaagg	Protospacer
 ..****. **********************   *

32. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
tttgactgcggctgcggctgcggctgcggctgaagg	Protospacer
 ..****. **********************   *

33. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
tttgactgcggctgcggctgcggctgcggctgaagg	Protospacer
 ..****. **********************   *

34. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
tttgactgcggctgcggctgcggctgcggctgaagg	Protospacer
 ..****. **********************   *

35. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
tttgactgcggctgcggctgcggctgcggctgaagg	Protospacer
 ..****. **********************   *

36. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
tttgactgcggctgcggctgcggctgcggctgaagg	Protospacer
 ..****. **********************   *

37. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
tttgactgcggctgcggctgcggctgcggctgaagg	Protospacer
 ..****. **********************   *

38. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
tttgactgcggctgcggctgcggctgcggctgaagg	Protospacer
 ..****. **********************   *

39. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
tttgactgcggctgcggctgcggctgcggctgaagg	Protospacer
 ..****. **********************   *

40. spacer 3.53|1918985|35|NC_018870|CRISPRCasFinder,CRT matches to NZ_CP025552 (Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

gccgcgaggcggacaagtgggcgccgaacttcgtc	CRISPR spacer
gtacgcaagcggacaagtgggcgctgaactacgag	Protospacer
*.    *.****************.***** **

41. spacer 3.165|1918986|35|NC_018870|PILER-CR matches to NZ_CP025552 (Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

gccgcgaggcggacaagtgggcgccgaacttcgtc	CRISPR spacer
gtacgcaagcggacaagtgggcgctgaactacgag	Protospacer
*.    *.****************.***** **

42. spacer 4.55|2208240|35|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 10, identity: 0.714

ttcaacctcgcgccgcgccttctcctgcgcggcct	CRISPR spacer
gcccctccgccgccgcgccctctccagcgcggcct	Protospacer
 .*  .*.  *********.***** *********

43. spacer 5.2|2439487|32|NC_018870|PILER-CR matches to NC_019694 (Oscillatoria acuminata PCC 6304 plasmid pOSCIL6304.02, complete sequence) position: , mismatch: 10, identity: 0.688

caggtttggcggttatttgttcctgaacgact	CRISPR spacer
attctttgggggttatttgttcgtgaataaaa	Protospacer
    ***** ************ ****..*

44. spacer 7.4|2447976|33|NC_018870|PILER-CR matches to NZ_CP053316 (Bacillus circulans strain GN03 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

gatattgttcaaactttgcattcatttcgttcc	CRISPR spacer
cgaattgctcaaactttgcattcactttacccg	Protospacer
 . ****.****************.**....*

45. spacer 8.19|2450927|36|NC_018870|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP032695 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence) position: , mismatch: 10, identity: 0.722

ggagagtttgctgctgatatatcgattgatcttcat	CRISPR spacer
ggatagtttgctgctgatgtatcgatcgccgccgtt	Protospacer
*** **************.*******.* . ..  *

46. spacer 10.2|2455774|36|NC_018870|CRT,CRISPRCasFinder matches to NZ_CP030772 (Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence) position: , mismatch: 10, identity: 0.722

atgtgccggaggtgtgcccgaactgcgcagatatcc	CRISPR spacer
aggtgccggtggtgtgcccggactgcgcaacgccgt	Protospacer
* ******* **********.********.   . .

47. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 10, identity: 0.722

------gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
tgtgattccggctgcggctgcggctgcggctgcggc------	Protospacer
       ***.**. *********************

48. spacer 10.39|2455796|33|NC_018870|PILER-CR matches to NZ_CP023976 (Streptomyces alboflavus strain MDJK44 plasmid pMDJK44.1, complete sequence) position: , mismatch: 10, identity: 0.697

tgtgccggaggtgtgcccgaactgcgcagatat	CRISPR spacer
gctgccggagcagtgcccgaactgcggcggcgc	Protospacer
  ********  **************  *....

49. spacer 3.74|1920531|35|NC_018870|CRISPRCasFinder,CRT matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 11, identity: 0.686

cgtgcttggcgtactggtccagctcgttcagatag	CRISPR spacer
tcgaggtggcgtactggaccagctcgtccagggaa	Protospacer
.  .  *********** *********.***. *.

50. spacer 3.74|1920531|35|NC_018870|CRISPRCasFinder,CRT matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 11, identity: 0.686

cgtgcttggcgtactggtccagctcgttcagatag	CRISPR spacer
tcgaggtggcgtactggaccagctcgtccagggaa	Protospacer
.  .  *********** *********.***. *.

51. spacer 3.74|1920531|35|NC_018870|CRISPRCasFinder,CRT matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 11, identity: 0.686

cgtgcttggcgtactggtccagctcgttcagatag	CRISPR spacer
tcgaggtggcgtactggaccagctcgtccagggaa	Protospacer
.  .  *********** *********.***. *.

52. spacer 3.76|1920679|35|NC_018870|CRISPRCasFinder,CRT matches to NC_019959 (Mycobacterium sp. JS623 plasmid pMYCSM03, complete sequence) position: , mismatch: 11, identity: 0.686

acctccgggtggatgccgccggcgccgacctgacc	CRISPR spacer
gcaaccgggtcgatgacgccggcgccgacgacgtt	Protospacer
.*  ****** **** *************   ...

53. spacer 3.186|1920532|35|NC_018870|PILER-CR matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 11, identity: 0.686

cgtgcttggcgtactggtccagctcgttcagatag	CRISPR spacer
tcgaggtggcgtactggaccagctcgtccagggaa	Protospacer
.  .  *********** *********.***. *.

54. spacer 3.186|1920532|35|NC_018870|PILER-CR matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 11, identity: 0.686

cgtgcttggcgtactggtccagctcgttcagatag	CRISPR spacer
tcgaggtggcgtactggaccagctcgtccagggaa	Protospacer
.  .  *********** *********.***. *.

55. spacer 3.186|1920532|35|NC_018870|PILER-CR matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 11, identity: 0.686

cgtgcttggcgtactggtccagctcgttcagatag	CRISPR spacer
tcgaggtggcgtactggaccagctcgtccagggaa	Protospacer
.  .  *********** *********.***. *.

56. spacer 3.188|1920680|35|NC_018870|PILER-CR matches to NC_019959 (Mycobacterium sp. JS623 plasmid pMYCSM03, complete sequence) position: , mismatch: 11, identity: 0.686

acctccgggtggatgccgccggcgccgacctgacc	CRISPR spacer
gcaaccgggtcgatgacgccggcgccgacgacgtt	Protospacer
.*  ****** **** *************   ...

57. spacer 4.85|2210227|36|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to MK448839 (Streptococcus phage Javan102, complete genome) position: , mismatch: 11, identity: 0.694

aaacaaactgctctattttcttttcttccattttat	CRISPR spacer
ctttcgatgtctttattttcttttcttccagtttat	Protospacer
   . .*.  **.***************** *****

58. spacer 4.85|2210227|36|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to MK448667 (Streptococcus phage Javan105, complete genome) position: , mismatch: 11, identity: 0.694

aaacaaactgctctattttcttttcttccattttat	CRISPR spacer
ctttcgatgtctttattttcttttcttccagtttat	Protospacer
   . .*.  **.***************** *****

59. spacer 4.85|2210227|36|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to MK448843 (Streptococcus phage Javan112, complete genome) position: , mismatch: 11, identity: 0.694

aaacaaactgctctattttcttttcttccattttat	CRISPR spacer
ctttcgatgtctttattttcttttcttccagtttat	Protospacer
   . .*.  **.***************** *****

60. spacer 4.85|2210227|36|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to MK448841 (Streptococcus phage Javan108, complete genome) position: , mismatch: 11, identity: 0.694

aaacaaactgctctattttcttttcttccattttat	CRISPR spacer
ctttcgatgtctttattttcttttcttccagtttat	Protospacer
   . .*.  **.***************** *****

61. spacer 4.100|2211218|37|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to LR877331 (Klebsiella phage vB_KpnM_311F genome assembly, chromosome: 1) position: , mismatch: 11, identity: 0.703

gctctt-----cggatttgaccatccagtccctactgttgaa	CRISPR spacer
-----taaagacggatttgaccatccagtcacaactgatatg	Protospacer
     *     ******************* * **** *. .

62. spacer 4.100|2211218|37|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to MN101226 (Klebsiella phage KPN2 HKu-2019, complete genome) position: , mismatch: 11, identity: 0.703

gctctt-----cggatttgaccatccagtccctactgttgaa	CRISPR spacer
-----taaagacggatttgaccatccagtcacaactgatatg	Protospacer
     *     ******************* * **** *. .

63. spacer 4.100|2211218|37|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to NC_031095 (Klebsiella phage PKO111, complete genome) position: , mismatch: 11, identity: 0.703

gctctt-----cggatttgaccatccagtccctactgttgaa	CRISPR spacer
-----taaagacggatttgaccatccagtcacaactgatatg	Protospacer
     *     ******************* * **** *. .

64. spacer 4.100|2211218|37|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to MH333064 (Klebsiella phage Mineola, complete genome) position: , mismatch: 11, identity: 0.703

gctctt-----cggatttgaccatccagtccctactgttgaa	CRISPR spacer
-----taaagacggatttgaccatccagtcacaactgatatg	Protospacer
     *     ******************* * **** *. .

65. spacer 4.100|2211218|37|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to MN434095 (Klebsiella pneumoniae phage JIPh_Kp122, complete genome) position: , mismatch: 11, identity: 0.703

gctctt-----cggatttgaccatccagtccctactgttgaa	CRISPR spacer
-----taaagacggatttgaccatccagtcacaactgatatg	Protospacer
     *     ******************* * **** *. .

66. spacer 4.100|2211218|37|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to MN101230 (Klebsiella phage KPN6, complete genome) position: , mismatch: 11, identity: 0.703

gctctt-----cggatttgaccatccagtccctactgttgaa	CRISPR spacer
-----taaagacggatttgaccatccagtcacaactgatatg	Protospacer
     *     ******************* * **** *. .

67. spacer 4.100|2211218|37|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to MN101229 (Klebsiella phage KPN5, complete genome) position: , mismatch: 11, identity: 0.703

gctctt-----cggatttgaccatccagtccctactgttgaa	CRISPR spacer
-----taaagacggatttgaccatccagtcacaactgatatg	Protospacer
     *     ******************* * **** *. .

68. spacer 4.100|2211218|37|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to KY000080 (Klebsiella phage KPV15, complete genome) position: , mismatch: 11, identity: 0.703

gctctt-----cggatttgaccatccagtccctactgttgaa	CRISPR spacer
-----taaagacggatttgaccatccagtcacaactgatatg	Protospacer
     *     ******************* * **** *. .

69. spacer 4.100|2211218|37|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to MG751100 (Klebsiella phage KP1, complete genome) position: , mismatch: 11, identity: 0.703

gctctt-----cggatttgaccatccagtccctactgttgaa	CRISPR spacer
-----taaagacggatttgaccatccagtcacaactgatatg	Protospacer
     *     ******************* * **** *. .

70. spacer 4.100|2211218|37|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to NC_028686 (Klebsiella phage JD18, complete genome) position: , mismatch: 11, identity: 0.703

gctctt-----cggatttgaccatccagtccctactgttgaa	CRISPR spacer
-----taaagacggatttgaccatccagtcacaactgatatg	Protospacer
     *     ******************* * **** *. .

71. spacer 4.100|2211218|37|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to MK421971 (Klebsiella phage vB_KpnM_GF, partial genome) position: , mismatch: 11, identity: 0.703

gctctt-----cggatttgaccatccagtccctactgttgaa	CRISPR spacer
-----taaagacggatttgaccatccagtcacaactgatatg	Protospacer
     *     ******************* * **** *. .

72. spacer 4.100|2211218|37|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to NC_031087 (Klebsiella phage vB_KpnM_KpV477, complete genome) position: , mismatch: 11, identity: 0.703

gctctt-----cggatttgaccatccagtccctactgttgaa	CRISPR spacer
-----taaagacggatttgaccatccagtcacaactgatatg	Protospacer
     *     ******************* * **** *. .

73. spacer 4.100|2211218|37|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to CP062992 (Klebsiella phage AShe-2020a, complete genome) position: , mismatch: 11, identity: 0.703

gctctt-----cggatttgaccatccagtccctactgttgaa	CRISPR spacer
-----taaagacggatttgaccatccagtcacaactgatatg	Protospacer
     *     ******************* * **** *. .

74. spacer 4.100|2211218|37|NC_018870|PILER-CR,CRISPRCasFinder,CRT matches to MH729874 (Klebsiella phage KP179, complete genome) position: , mismatch: 12, identity: 0.676

gctctt-----cggatttgaccatccagtccctactgttgaa	CRISPR spacer
-----taaagacggatttgaccatccagtcacaactgacatg	Protospacer
     *     ******************* * **** .. .

75. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 12, identity: 0.667

------gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
catttttttggctgcggctgcggctgcggctgcggc------	Protospacer
       ..*.**. *********************

76. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 12, identity: 0.667

------gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
catttttttggctgcggctgcggctgcggctgcggc------	Protospacer
       ..*.**. *********************

77. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 12, identity: 0.667

------gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
catttttttggctgcggctgcggctgcggctgcggc------	Protospacer
       ..*.**. *********************

78. spacer 10.13|2456501|36|NC_018870|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 12, identity: 0.667

------gccgactaaggctgcggctgcggctgcggctcctgc	CRISPR spacer
catttttttggctgcggctgcggctgcggctgcggc------	Protospacer
       ..*.**. *********************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

444111 : 481434

Geobacillus_virus(40.0%)

protease,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015049595.1\|444111_444513_+\|transposase	IS200/IS605 family transposase	A0A0H3UZM0	Geobacillus_virus	4.2e-32	50.4
WP_015049596.1\|444518_445757_+\|transposase	transposase	A0A0H3UZC2	Geobacillus_virus	6.9e-09	23.9
WP_037999118.1\|445781_447296_+	energy-coupling factor ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.6e-18	35.2
WP_015049598.1\|447302_448136_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_015049599.1\|448204_448945_+	protein kinase	NA	NA	NA	NA
WP_015049600.1\|449059_450289_-	hypothetical protein	NA	NA	NA	NA
WP_015049601.1\|450248_453656_-	SMC domain-containing protein	NA	NA	NA	NA
WP_015049602.1\|453659_454304_-	DUF4194 domain-containing protein	NA	NA	NA	NA
WP_015049603.1\|454276_455698_-	hypothetical protein	NA	NA	NA	NA
WP_037999593.1\|455930_456278_+	LysM peptidoglycan-binding domain-containing protein	M1HNA7	Bacillus_virus	9.0e-07	37.4
WP_037999117.1\|456834_458595_+	chloride channel protein	NA	NA	NA	NA
WP_015049606.1\|458986_459796_-	arsenite methyltransferase	NA	NA	NA	NA
WP_081578570.1\|459811_460345_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_158502687.1\|460373_460478_+	hypothetical protein	NA	NA	NA	NA
WP_015049608.1\|460979_462470_+	trimethylamine methyltransferase family protein	NA	NA	NA	NA
WP_015049609.1\|462545_463385_-	phosphoenolpyruvate hydrolase family protein	NA	NA	NA	NA
WP_015049610.1\|463425_464769_-	Tm-1-like ATP-binding domain-containing protein	NA	NA	NA	NA
WP_015049611.1\|464765_465542_-	2-phosphosulfolactate phosphatase	NA	NA	NA	NA
WP_015049612.1\|465614_466457_-	phosphoenolpyruvate hydrolase family protein	NA	NA	NA	NA
WP_015049613.1\|466480_467797_-	2,3-diketo-5-methylthiopentyl-1-phosphate enolase	NA	NA	NA	NA
WP_015049614.1\|468140_468731_-	glycerol-3-phosphate responsive antiterminator	NA	NA	NA	NA
WP_028991325.1\|468872_469109_-	ferrous iron transport protein A	NA	NA	NA	NA
WP_015049616.1\|469462_470929_-	ferrous iron transporter B	NA	NA	NA	NA
WP_148275820.1\|470906_471557_-	50S ribosome-binding GTPase	NA	NA	NA	NA
WP_015049618.1\|472089_472368_+	DUF4405 domain-containing protein	NA	NA	NA	NA
WP_015049619.1\|473008_473410_+\|transposase	IS200/IS605 family transposase	A0A0H3UZM0	Geobacillus_virus	3.8e-33	51.1
WP_015049620.1\|473415_474654_+\|transposase	transposase	A0A0H3UZC2	Geobacillus_virus	5.3e-09	23.9
WP_148275821.1\|474678_475281_+	hypothetical protein	A0A2H4J162	uncultured_Caudovirales_phage	5.0e-05	34.3
WP_015049623.1\|476035_477439_+	trigger factor	NA	NA	NA	NA
WP_015049624.1\|477568_478174_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	2.2e-53	51.7
WP_015049625.1\|478200_479460_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.7e-148	63.3
WP_148275951.1\|479808_481434_+\|protease	ATP-dependent protease LonB	E3T507	Cafeteria_roenbergensis_virus	1.7e-15	24.8

DBSCAN-SWA_2

764278 : 813703

Erysipelothrix_phage(40.0%)

integrase,transposase

attL 758083:758098|attR 789139:789154

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
758083:758098	attL	NA	NA	NA	NA
WP_012281358.1\|764278_765544_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_012281357.1\|765527_766508_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_012281356.1\|766497_767547_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_012281355.1\|767776_768118_+	DUF3852 domain-containing protein	NA	NA	NA	NA
WP_015049869.1\|768192_769050_+	hypothetical protein	NA	NA	NA	NA
WP_012281353.1\|769046_769616_+	hypothetical protein	A0A2K5B270	Erysipelothrix_phage	1.0e-20	47.5
WP_012281352.1\|769629_769932_+	hypothetical protein	NA	NA	NA	NA
WP_012281351.1\|769928_770519_+	hypothetical protein	NA	NA	NA	NA
WP_015049870.1\|770628_770820_+	hypothetical protein	NA	NA	NA	NA
WP_012281349.1\|770803_771439_+	Fic family protein	NA	NA	NA	NA
WP_012281348.1\|771618_773451_+	DUF87 domain-containing protein	NA	NA	NA	NA
WP_015049871.1\|773518_774565_+	amidoligase family protein	A0A2K9V489	Faecalibacterium_phage	3.1e-63	45.9
WP_012281341.1\|774584_775079_+	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_012281340.1\|775083_776169_+	M23 family metallopeptidase	I2E8W3	Clostridium_phage	1.9e-26	50.4
WP_012281339.1\|776186_776552_+	hypothetical protein	NA	NA	NA	NA
WP_012281338.1\|776585_777467_+	ParM/StbA family protein	NA	NA	NA	NA
WP_012281337.1\|777471_777765_+	hypothetical protein	NA	NA	NA	NA
WP_012281336.1\|777875_778133_+	hypothetical protein	NA	NA	NA	NA
WP_015049873.1\|778551_778959_+	hypothetical protein	NA	NA	NA	NA
WP_015049874.1\|778970_780746_+	sel1 repeat family protein	NA	NA	NA	NA
WP_015049876.1\|780892_782374_+	toprim domain-containing protein	NA	NA	NA	NA
WP_081578713.1\|782511_784305_+	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_015049878.1\|784315_784582_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015049879.1\|784749_784893_+	hypothetical protein	NA	NA	NA	NA
WP_155990788.1\|785017_785170_+	hypothetical protein	NA	NA	NA	NA
WP_015049881.1\|785147_785741_+	rubrerythrin family protein	NA	NA	NA	NA
WP_015049882.1\|785791_786172_+	desulfoferrodoxin	NA	NA	NA	NA
WP_028991093.1\|786486_787533_+	SH3 domain-containing protein	NA	NA	NA	NA
WP_148275961.1\|787735_788116_+	hypothetical protein	NA	NA	NA	NA
WP_015049885.1\|788162_788390_+	DNA-binding protein	NA	NA	NA	NA
WP_015049886.1\|788393_791549_+	site-specific DNA-methyltransferase	Q1MVP0	Enterobacteria_phage	2.4e-29	26.1
789139:789154	attR	NA	NA	NA	NA
WP_015049887.1\|791551_794749_+	DEAD/DEAH box helicase family protein	NA	NA	NA	NA
WP_015049888.1\|795114_796068_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	8.7e-20	28.2
WP_015049889.1\|796064_796469_-	hypothetical protein	NA	NA	NA	NA
WP_015049890.1\|796698_797142_+	hypothetical protein	NA	NA	NA	NA
WP_015049892.1\|797536_798892_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_015049893.1\|798920_799166_+	hypothetical protein	NA	NA	NA	NA
WP_037999497.1\|799487_801134_+	diguanylate cyclase	A0A127AWB9	Bacillus_phage	2.8e-18	33.3
WP_028991090.1\|801299_801809_-	ImmA/IrrE family metallo-endopeptidase	S6B1N5	Thermus_phage	7.9e-20	40.3
WP_015049896.1\|801825_802275_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015049897.1\|802423_802969_+	hypothetical protein	NA	NA	NA	NA
WP_015049898.1\|803291_803696_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_015049899.1\|804283_804673_+	recombinase family protein	NA	NA	NA	NA
WP_015049900.1\|804686_804848_+	hypothetical protein	NA	NA	NA	NA
WP_015049901.1\|804920_806531_+	recombinase family protein	A0A2K5B2B2	Erysipelothrix_phage	1.5e-88	36.9
WP_015049902.1\|806532_807408_+	recombinase family protein	A0A2K5B2B2	Erysipelothrix_phage	1.6e-07	26.0
WP_015049903.1\|807401_809075_+	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	4.1e-105	45.4
WP_015049904.1\|809422_811135_-\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_081578592.1\|811378_811558_+	DNA-binding protein	NA	NA	NA	NA
WP_028991087.1\|811572_811929_+	hypothetical protein	NA	NA	NA	NA
WP_148275834.1\|811938_812550_+	hypothetical protein	NA	NA	NA	NA
WP_015049905.1\|812803_813703_-\|transposase	IS3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

1358295 : 1369410

Staphylococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015050435.1\|1358295_1360011_+	DNA polymerase/3'-5' exonuclease PolX	A0A0G2Y568	Acanthamoeba_polyphaga_mimivirus	1.1e-07	24.4
WP_015050436.1\|1360035_1360989_+	NIF3 (NGG1p interacting factor 3)-like protein	NA	NA	NA	NA
WP_015050437.1\|1361009_1361426_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	1.3e-12	38.7
WP_015050438.1\|1361447_1361822_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	2.6e-12	36.4
WP_015050439.1\|1361842_1362163_+	DUF190 domain-containing protein	NA	NA	NA	NA
WP_015050440.1\|1362167_1364732_+	U32 family peptidase	Q6DW11	Phage_TP	5.6e-29	29.0
WP_015050441.1\|1364724_1367106_+	endonuclease MutS2	F2QAF7	Pyramimonas_orientalis_virus	3.6e-14	25.6
WP_015050442.1\|1367343_1368000_+	SOS response-associated peptidase	A0A1P8CX02	Bacillus_phage	1.7e-22	37.2
WP_148275972.1\|1368168_1368642_+	macro domain-containing protein	A0A2R3SV02	Bat_SARS-like_coronavirus	3.7e-11	38.2
WP_015050444.1\|1368657_1369410_+	histone deacetylase	S5M4R0	Bacillus_phage	2.2e-26	31.5

DBSCAN-SWA_4

1383853 : 1439417

Staphylococcus_phage(33.33%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015050459.1\|1383853_1385062_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_015050461.1\|1386315_1387008_+	hypothetical protein	NA	NA	NA	NA
WP_015050462.1\|1387034_1387316_-	late competence development ComFB family protein	NA	NA	NA	NA
WP_158502670.1\|1387710_1387872_-\|transposase	transposase	NA	NA	NA	NA
WP_015050464.1\|1388154_1388760_+	transcriptional repressor LexA	A0A1B1P7Q3	Bacillus_phage	3.1e-15	61.8
WP_015050465.1\|1388786_1389269_-	DUF456 domain-containing protein	NA	NA	NA	NA
WP_015050466.1\|1389307_1390267_-	acetyl-CoA carboxylase carboxyltransferase subunit alpha	NA	NA	NA	NA
WP_015050467.1\|1390269_1391133_-	acetyl-CoA carboxylase carboxyltransferase subunit beta	NA	NA	NA	NA
WP_015050468.1\|1391139_1391556_-	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_015050469.1\|1391587_1392832_-	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_015050470.1\|1392862_1393594_-	3-oxoacyl-[acyl-carrier-protein] reductase	A0A0N9R355	Chrysochromulina_ericina_virus	1.5e-08	25.5
WP_015050471.1\|1393590_1394526_-	ACP S-malonyltransferase	NA	NA	NA	NA
WP_028990992.1\|1394513_1395464_-	enoyl-[acyl-carrier-protein] reductase FabK	NA	NA	NA	NA
WP_015050473.1\|1395472_1396456_-	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_015050476.1\|1397961_1398900_-	AAA family ATPase	G3MAX6	Bacillus_virus	9.7e-56	47.0
WP_015050477.1\|1398946_1399705_-	ABC transporter permease	NA	NA	NA	NA
WP_015050478.1\|1399691_1400450_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.9e-30	37.0
WP_015050479.1\|1400466_1401453_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014162180.1\|1401561_1402794_-\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	5.2e-142	62.0
WP_015050480.1\|1402878_1403151_-	RNA chaperone Hfq	NA	NA	NA	NA
WP_015050481.1\|1403188_1404133_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_015050482.1\|1404150_1405878_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	2.9e-66	32.6
WP_081578627.1\|1405902_1407315_-	histone deacetylase	A0A2K9L2T7	Tupanvirus	6.9e-29	37.9
WP_015050484.1\|1407256_1408936_-	hydantoinase/oxoprolinase family protein	NA	NA	NA	NA
WP_037999028.1\|1408963_1411588_-	DNA mismatch repair protein MutS	A0A2P0VN50	Tetraselmis_virus	4.7e-39	23.4
WP_015050486.1\|1411628_1412000_-	YlbF family regulator	NA	NA	NA	NA
WP_148275872.1\|1412029_1413358_-\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_015050488.1\|1413480_1414077_-	hypothetical protein	NA	NA	NA	NA
WP_015050489.1\|1419656_1420568_+	DUF4338 domain-containing protein	NA	NA	NA	NA
WP_015050490.1\|1422259_1422448_+	50S ribosomal protein L28	NA	NA	NA	NA
WP_015050491.1\|1422444_1423008_-	phosphodiesterase	NA	NA	NA	NA
WP_015050492.1\|1422985_1423489_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	2.2e-38	51.7
WP_015050493.1\|1423503_1424718_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.1e-107	51.5
WP_015050494.1\|1424742_1425393_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.5e-39	46.0
WP_015050495.1\|1425374_1426523_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.0e-51	38.4
WP_028990991.1\|1427063_1427267_+	hypothetical protein	NA	NA	NA	NA
WP_028990990.1\|1428716_1429571_-	LuxR family transcriptional regulator	NA	NA	NA	NA
WP_015050500.1\|1430877_1431291_-\|transposase	transposase	NA	NA	NA	NA
WP_028990989.1\|1431732_1432086_-	hypothetical protein	NA	NA	NA	NA
WP_148275974.1\|1432222_1432498_-	EamA family transporter	NA	NA	NA	NA
WP_015050503.1\|1432487_1433024_-	glycosyltransferase	NA	NA	NA	NA
WP_015050504.1\|1433608_1434166_+	hypothetical protein	NA	NA	NA	NA
WP_158502671.1\|1436978_1438238_-	glycosyltransferase family 39 protein	NA	NA	NA	NA
WP_015050508.1\|1438426_1438750_+\|transposase	transposase	NA	NA	NA	NA
WP_015050509.1\|1438946_1439417_+\|transposase	IS3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

1746181 : 1782574

Bacillus_virus(25.0%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148275990.1\|1746181_1747567_-\|transposase	transposase family protein	NA	NA	NA	NA
WP_015050489.1\|1747559_1748471_-	DUF4338 domain-containing protein	NA	NA	NA	NA
WP_015050807.1\|1748884_1749910_-	AI-2E family transporter	NA	NA	NA	NA
WP_015050808.1\|1749942_1750131_-	YtxH domain-containing protein	NA	NA	NA	NA
WP_015050809.1\|1750133_1750316_-	hypothetical protein	NA	NA	NA	NA
WP_028990934.1\|1750278_1750815_-	PRC-barrel domain-containing protein	NA	NA	NA	NA
WP_037999287.1\|1750957_1752016_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_015050812.1\|1752055_1753219_-	cysteine desulfurase	NA	NA	NA	NA
WP_015050813.1\|1753271_1754606_-	replication-associated recombination protein A	G3MBE0	Bacillus_virus	6.1e-104	46.5
WP_015050814.1\|1754673_1755003_-	thioredoxin	A0A1X9I9P5	Staphylococcus_phage	1.3e-18	45.6
WP_155990775.1\|1755097_1755241_-	hypothetical protein	NA	NA	NA	NA
WP_015050815.1\|1755327_1755552_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015050816.1\|1755764_1756988_+	hypothetical protein	NA	NA	NA	NA
WP_015050817.1\|1757012_1758752_+	VWA domain-containing protein	NA	NA	NA	NA
WP_015050818.1\|1758748_1760641_-\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
WP_015050819.1\|1760988_1761663_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_148275991.1\|1762387_1763242_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_015050822.1\|1763246_1763915_+	accessory gene regulator B family protein	NA	NA	NA	NA
WP_148275875.1\|1763886_1764597_+	response regulator	NA	NA	NA	NA
WP_015050823.1\|1764802_1764931_+	cyclic lactone autoinducer peptide	NA	NA	NA	NA
WP_015050824.1\|1765163_1765568_+	hypothetical protein	NA	NA	NA	NA
WP_015050825.1\|1765560_1765959_+	hypothetical protein	NA	NA	NA	NA
WP_015050826.1\|1765952_1766696_+	hypothetical protein	NA	NA	NA	NA
WP_148275889.1\|1766703_1767105_+	hypothetical protein	NA	NA	NA	NA
WP_015050828.1\|1767251_1767584_+\|transposase	transposase	NA	NA	NA	NA
WP_158502679.1\|1767519_1767771_+\|transposase	transposase	NA	NA	NA	NA
WP_015050829.1\|1767724_1768417_+\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	7.0e-19	32.7
WP_148275890.1\|1768937_1769390_+	hypothetical protein	NA	NA	NA	NA
WP_015050831.1\|1770345_1771197_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015050832.1\|1771386_1772997_+	hypothetical protein	NA	NA	NA	NA
WP_015050833.1\|1773097_1774339_+	hypothetical protein	NA	NA	NA	NA
WP_015050834.1\|1774850_1775582_+	hypothetical protein	NA	NA	NA	NA
WP_015050835.1\|1775681_1775984_+	hypothetical protein	NA	NA	NA	NA
WP_015050836.1\|1775989_1777795_+	hypothetical protein	NA	NA	NA	NA
WP_081578644.1\|1778875_1779004_+	cyclic lactone autoinducer peptide	NA	NA	NA	NA
WP_148275891.1\|1779311_1780157_+	hypothetical protein	NA	NA	NA	NA
WP_081578718.1\|1780532_1780622_+	cyclic lactone autoinducer peptide	NA	NA	NA	NA
WP_148275892.1\|1780631_1781201_+	hypothetical protein	NA	NA	NA	NA
WP_015050840.1\|1781248_1781764_+	hypothetical protein	NA	NA	NA	NA
WP_148275992.1\|1782193_1782574_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1P8DJG9	Virus_Rctr71	6.1e-25	47.5

DBSCAN-SWA_6

1967900 : 2036129

Streptococcus_phage(22.22%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015051015.1\|1967900_1969124_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	7.0e-54	41.7
WP_158502681.1\|1969360_1969636_-	PocR ligand-binding domain-containing protein	NA	NA	NA	NA
WP_015051017.1\|1969743_1971762_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_015051018.1\|1972005_1972293_-	MoaD family protein	NA	NA	NA	NA
WP_015051019.1\|1972316_1972715_-	tungsten-containing aldehyde ferredoxin oxidoreductase Aor	NA	NA	NA	NA
WP_015051020.1\|1972930_1973920_-	lipoate--protein ligase	A0A2H4UVX5	Bodo_saltans_virus	6.5e-10	28.2
WP_015051021.1\|1973939_1974488_-	isochorismatase family protein	NA	NA	NA	NA
WP_015051022.1\|1974536_1975295_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_015051023.1\|1975291_1976293_-	radical SAM protein	NA	NA	NA	NA
WP_148276002.1\|1976279_1977317_-	radical SAM protein	NA	NA	NA	NA
WP_015051025.1\|1977616_1978723_-	biotin/lipoate A/B protein ligase	NA	NA	NA	NA
WP_015051026.1\|1978719_1979148_-	glycine cleavage system protein GcvH	NA	NA	NA	NA
WP_015051027.1\|1979167_1980121_-	lipoate--protein ligase family protein	NA	NA	NA	NA
WP_015051028.1\|1980147_1980453_-	hypothetical protein	NA	NA	NA	NA
WP_015051029.1\|1980484_1981654_-	(Fe-S)-binding protein	NA	NA	NA	NA
WP_028990896.1\|1981650_1983108_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_015051031.1\|1983164_1983587_-	glycine cleavage system protein H	NA	NA	NA	NA
WP_015051032.1\|1983618_1983963_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_015051033.1\|1984015_1985173_-	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
WP_015051034.1\|1985188_1986199_-	NAD(+)/NADH kinase	NA	NA	NA	NA
WP_015051035.1\|1986271_1987243_-	alpha-ketoacid dehydrogenase subunit beta	NA	NA	NA	NA
WP_015051036.1\|1987265_1988228_-	thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha	NA	NA	NA	NA
WP_015051037.1\|1988248_1989307_-	2,3-butanediol dehydrogenase	NA	NA	NA	NA
WP_014162180.1\|1989427_1990660_-\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	5.2e-142	62.0
WP_015051038.1\|1990863_1991229_-	Lin0512 family protein	NA	NA	NA	NA
WP_015051039.1\|1992193_1992391_+	hypothetical protein	NA	NA	NA	NA
WP_015051040.1\|1992820_1994065_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	1.1e-54	42.3
WP_015051042.1\|1995091_1996918_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	M1HMK6	Paramecium_bursaria_Chlorella_virus	2.1e-115	39.1
WP_015051043.1\|1997240_1998617_-	phosphoglucosamine mutase	NA	NA	NA	NA
WP_015051044.1\|1998665_1999619_-	hypothetical protein	NA	NA	NA	NA
WP_015051045.1\|1999620_2000412_-	TIGR00159 family protein	NA	NA	NA	NA
WP_148276003.1\|2000583_2001906_+	MFS transporter	NA	NA	NA	NA
WP_015051047.1\|2001977_2002715_+	DUF881 domain-containing protein	NA	NA	NA	NA
WP_015051048.1\|2002718_2003102_+	small basic family protein	NA	NA	NA	NA
WP_015051049.1\|2003088_2003778_+	DUF881 domain-containing protein	NA	NA	NA	NA
WP_015051050.1\|2003857_2005456_-	citramalate synthase	NA	NA	NA	NA
WP_015051051.1\|2005574_2006648_-	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
WP_015051052.1\|2006640_2007141_-	3-isopropylmalate dehydratase small subunit	NA	NA	NA	NA
WP_028990894.1\|2007130_2008405_-	3-isopropylmalate dehydratase large subunit	NA	NA	NA	NA
WP_015051054.1\|2008401_2009928_-	2-isopropylmalate synthase	E5EQ69	Micromonas_sp._RCC1109_virus	3.6e-07	43.4
WP_015051055.1\|2009930_2010929_-	ketol-acid reductoisomerase	NA	NA	NA	NA
WP_015051056.1\|2010932_2011436_-	acetolactate synthase small subunit	NA	NA	NA	NA
WP_015051057.1\|2011441_2013109_-	biosynthetic-type acetolactate synthase large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	1.6e-69	34.7
WP_049886180.1\|2013077_2014793_-	dihydroxy-acid dehydratase	NA	NA	NA	NA
WP_015051059.1\|2014974_2015862_-	branched-chain-amino-acid transaminase	NA	NA	NA	NA
WP_028990893.1\|2016544_2016934_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_015051061.1\|2016998_2017412_+	hypothetical protein	NA	NA	NA	NA
WP_015051063.1\|2017501_2018335_-	hypothetical protein	NA	NA	NA	NA
WP_015051064.1\|2018303_2019923_-	recombinase family protein	A0A0S2SXR4	Bacillus_phage	6.9e-25	24.8
WP_015051065.1\|2019919_2020093_-	hypothetical protein	NA	NA	NA	NA
WP_158502682.1\|2020557_2021403_-	hypothetical protein	NA	NA	NA	NA
WP_015051067.1\|2022101_2023163_-	SWIM zinc finger family protein	NA	NA	NA	NA
WP_015051068.1\|2023630_2024113_-	DUF3368 domain-containing protein	NA	NA	NA	NA
WP_015051069.1\|2024096_2024387_-	UPF0175 family protein	NA	NA	NA	NA
WP_015050843.1\|2025788_2027231_-\|transposase	ISLre2-like element ISTph1 family transposase	NA	NA	NA	NA
WP_015051072.1\|2028046_2029768_-	DUF262 domain-containing protein	NA	NA	NA	NA
WP_015051073.1\|2029806_2029920_-	hypothetical protein	NA	NA	NA	NA
WP_015051076.1\|2031360_2032692_-\|transposase	transposase	NA	NA	NA	NA
WP_015051079.1\|2033984_2034473_-	hypothetical protein	NA	NA	NA	NA
WP_015051080.1\|2034908_2036129_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	9.4e-51	31.6

DBSCAN-SWA_7

2187017 : 2254623

Staphylococcus_phage(20.0%)

protease,transposase,integrase

attL 2206384:2206400|attR 2239862:2239878

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_028990855.1\|2187017_2187380_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_015051228.1\|2187372_2187735_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_015051229.1\|2187899_2189918_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_015051231.1\|2190747_2192223_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_015051232.1\|2192325_2192508_+	hypothetical protein	NA	NA	NA	NA
WP_015051233.1\|2192652_2193525_+	NAD(+)/NADH kinase	NA	NA	NA	NA
WP_148276009.1\|2193574_2194084_+	NADH-quinone oxidoreductase subunit NuoE	NA	NA	NA	NA
WP_015051235.1\|2194080_2195835_+	NADH-quinone oxidoreductase subunit NuoF	NA	NA	NA	NA
WP_015051236.1\|2195852_2199329_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_015051237.1\|2199699_2200098_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_015051238.1\|2200230_2200668_-	cupin domain-containing protein	NA	NA	NA	NA
WP_015051239.1\|2200687_2201218_-	flavodoxin	NA	NA	NA	NA
WP_015051240.1\|2201259_2202123_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	4.9e-54	41.2
WP_015051241.1\|2202147_2203353_-	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
2206384:2206400	attL	NA	NA	NA	NA
WP_015051245.1\|2212251_2212671_+	hypothetical protein	NA	NA	NA	NA
WP_015051246.1\|2212673_2212898_+	hypothetical protein	NA	NA	NA	NA
WP_015051186.1\|2213389_2213770_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1P8DJG9	Virus_Rctr71	5.5e-26	49.2
WP_015051248.1\|2214587_2214824_-	VanW family protein	NA	NA	NA	NA
WP_015051249.1\|2215117_2215693_+	manganese catalase family protein	NA	NA	NA	NA
WP_028990850.1\|2215756_2216146_-	hypothetical protein	NA	NA	NA	NA
WP_015051250.1\|2216224_2217454_-	multidrug effflux MFS transporter	NA	NA	NA	NA
WP_015051251.1\|2218185_2218614_-	hypothetical protein	NA	NA	NA	NA
WP_015051252.1\|2218637_2218844_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015051253.1\|2219325_2219844_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_015051254.1\|2220008_2221502_-	nitrilase/cyanide hydratase	NA	NA	NA	NA
WP_015051256.1\|2223476_2224166_-	hypothetical protein	NA	NA	NA	NA
WP_015051259.1\|2224926_2225244_-	hypothetical protein	NA	NA	NA	NA
WP_015051260.1\|2225726_2225900_+	hypothetical protein	NA	NA	NA	NA
WP_028990845.1\|2226745_2226928_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015051263.1\|2227018_2228185_+\|integrase	site-specific integrase	A0A2H4JCB7	uncultured_Caudovirales_phage	4.1e-64	37.3
WP_015051264.1\|2228447_2230496_-\|protease	protease Lon-related BREX system protein BrxL	NA	NA	NA	NA
WP_015051265.1\|2230499_2232854_-	BREX-1 system phosphatase PglZ type B	NA	NA	NA	NA
WP_015051266.1\|2232856_2236261_-	restriction endonuclease subunit M	NA	NA	NA	NA
WP_015051267.1\|2236274_2239721_-	BREX system P-loop protein BrxC	NA	NA	NA	NA
WP_015051268.1\|2239717_2240281_-	DUF1788 domain-containing protein	NA	NA	NA	NA
2239862:2239878	attR	NA	NA	NA	NA
WP_049886184.1\|2240273_2241098_-	hypothetical protein	NA	NA	NA	NA
WP_155990774.1\|2241343_2241499_-	hypothetical protein	NA	NA	NA	NA
WP_014162180.1\|2242446_2243679_-\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	5.2e-142	62.0
WP_158502684.1\|2243948_2245784_+	hypothetical protein	NA	NA	NA	NA
WP_037999200.1\|2246842_2247739_-	DMT family transporter	NA	NA	NA	NA
WP_015051273.1\|2247877_2248714_+	basic amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_015051274.1\|2248829_2249543_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_028990842.1\|2249529_2250252_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.9e-35	39.5
WP_148275905.1\|2250386_2250956_-	hypothetical protein	NA	NA	NA	NA
WP_015051277.1\|2250980_2251406_-	flagellar protein FliT	NA	NA	NA	NA
WP_015051278.1\|2251441_2251834_-	flagellar export chaperone FliS	NA	NA	NA	NA
WP_015051279.1\|2251879_2252254_-	flagellar protein FlaG	NA	NA	NA	NA
WP_015051280.1\|2252324_2253029_-	flagellar filament capping protein FliD	NA	NA	NA	NA
WP_015051076.1\|2253291_2254623_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_8

2302466 : 2359733

Erysipelothrix_phage(67.86%)

tail,holin,transposase,portal,protease,terminase,capsid,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015051329.1\|2302466_2302943_-\|protease	hydrogenase maturation protease	NA	NA	NA	NA
WP_015051330.1\|2303149_2303812_-	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_028990829.1\|2303833_2304721_-	GTPase Era	NA	NA	NA	NA
WP_015051332.1\|2304727_2305135_-	cytidine deaminase	NA	NA	NA	NA
WP_015051333.1\|2305157_2305523_-	diacylglycerol kinase family protein	NA	NA	NA	NA
WP_015051334.1\|2305519_2306008_-	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_015051335.1\|2305988_2308166_-	HDIG domain-containing protein	NA	NA	NA	NA
WP_015051336.1\|2308200_2309169_-	PhoH family protein	A0A0S0MVD6	Pseudomonas_phage	4.8e-50	48.8
WP_015051337.1\|2309165_2310425_-	sporulation protein YqfD	NA	NA	NA	NA
WP_037998885.1\|2310451_2310757_-	sporulation protein YqfC	NA	NA	NA	NA
WP_028990828.1\|2310856_2311318_-	GatB/YqeY domain-containing protein	A0A0K2FLI9	Brevibacillus_phage	2.9e-13	36.0
WP_015051340.1\|2311330_2311507_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_015051341.1\|2311695_2312154_-	arginine decarboxylase, pyruvoyl-dependent	NA	NA	NA	NA
WP_015051342.1\|2312296_2312815_+	hypothetical protein	NA	NA	NA	NA
WP_015051343.1\|2312839_2313475_+	coenzyme F420-0:L-glutamate ligase	NA	NA	NA	NA
WP_148275909.1\|2313954_2314260_+	hypothetical protein	NA	NA	NA	NA
WP_015051345.1\|2314394_2315807_-	HD domain-containing protein	B5LJ39	Mycobacterium_phage	3.3e-15	24.5
WP_015051346.1\|2316498_2317452_-	aminopeptidase	NA	NA	NA	NA
WP_015051347.1\|2317534_2318545_-	MBL fold metallo-hydrolase	Q0H255	Geobacillus_phage	1.5e-65	47.7
WP_015051348.1\|2318555_2318756_-	DUF3006 domain-containing protein	Q0H256	Geobacillus_phage	1.3e-10	49.2
WP_037998881.1\|2318877_2319204_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_015051350.1\|2319425_2319938_-	TIGR00725 family protein	NA	NA	NA	NA
WP_155990773.1\|2320647_2320794_-	hypothetical protein	NA	NA	NA	NA
WP_028990826.1\|2320901_2321279_+	hypothetical protein	NA	NA	NA	NA
WP_015051353.1\|2322010_2322775_-\|transposase	transposase	NA	NA	NA	NA
WP_148275910.1\|2324488_2326756_-	DUF262 domain-containing protein	NA	NA	NA	NA
WP_015051357.1\|2326739_2328425_-	DUF262 domain-containing protein	NA	NA	NA	NA
WP_015051358.1\|2328458_2328860_-	hypothetical protein	NA	NA	NA	NA
WP_015051359.1\|2329009_2330578_-	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	1.9e-168	57.3
WP_015051360.1\|2330540_2331032_-	recombinase	A0A2K5B2B3	Erysipelothrix_phage	4.8e-22	43.1
WP_015051361.1\|2330995_2332564_-	recombinase family protein	A0A2K5B2B2	Erysipelothrix_phage	3.3e-149	52.1
WP_012208274.1\|2332625_2332844_-	hypothetical protein	NA	NA	NA	NA
WP_015051362.1\|2332897_2333902_-	N-acetylmuramoyl-L-alanine amidase	H7BV89	unidentified_phage	5.4e-12	71.4
WP_015051363.1\|2333898_2334318_-\|holin	phage holin family protein	A0A2K5B2A2	Erysipelothrix_phage	1.6e-50	67.6
WP_015051364.1\|2334419_2337398_-	polysaccharide deacetylase family protein	A0A2I6PHU4	Pseudomonas_phage	1.0e-21	21.4
WP_015051365.1\|2337402_2338755_-\|tail	phage tail protein	B2VQ46	Geobacillus_phage	6.1e-27	30.2
WP_015051366.1\|2338754_2339969_-\|tail	phage tail family protein	NA	NA	NA	NA
WP_015051368.1\|2342182_2342374_-	hypothetical protein	A0A2K5B296	Erysipelothrix_phage	3.3e-11	70.7
WP_014256679.1\|2342370_2342754_-	hypothetical protein	A0A2K5B295	Erysipelothrix_phage	5.7e-39	68.0
WP_004464008.1\|2342753_2343353_-\|tail	phage tail protein	A0A2K5B294	Erysipelothrix_phage	3.1e-79	74.2
WP_015051369.1\|2343358_2343703_-	hypothetical protein	A0A2K5B293	Erysipelothrix_phage	9.7e-30	55.0
WP_015051370.1\|2343699_2344131_-	HK97 gp10 family phage protein	A0A2K5B292	Erysipelothrix_phage	1.2e-45	62.2
WP_015051371.1\|2344147_2344483_-\|head,tail	head-tail adaptor protein	A0A2K5B291	Erysipelothrix_phage	3.1e-28	56.0
WP_015051372.1\|2344485_2344794_-\|head,tail	phage gp6-like head-tail connector protein	A0A2K5B290	Erysipelothrix_phage	8.7e-38	74.5
WP_015051373.1\|2344815_2346018_-\|capsid	phage major capsid protein	A0A2I4R671	Erysipelothrix_phage	7.1e-176	77.9
WP_003516023.1\|2346031_2346757_-\|protease	Clp protease ClpP	A0A2K5B288	Erysipelothrix_phage	8.5e-76	64.1
WP_015051374.1\|2346695_2348018_-\|portal	phage portal protein	A0A2K5B287	Erysipelothrix_phage	3.0e-188	75.2
WP_015051375.1\|2348125_2348530_+	hypothetical protein	NA	NA	NA	NA
WP_015051376.1\|2348526_2351193_-\|terminase	terminase	A0A2K5B285	Erysipelothrix_phage	3.5e-26	75.0
WP_015051377.1\|2351247_2351442_-	DUF5049 domain-containing protein	NA	NA	NA	NA
WP_015051378.1\|2351445_2351913_-	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_015051379.1\|2351977_2352877_-	amidoligase family protein	A0A2K9V489	Faecalibacterium_phage	1.5e-53	41.8
WP_015051380.1\|2353018_2353249_-	DUF4314 domain-containing protein	NA	NA	NA	NA
WP_003516007.1\|2353245_2353581_-	hypothetical protein	NA	NA	NA	NA
WP_003516004.1\|2353573_2354266_-	hypothetical protein	A0A2K5B280	Erysipelothrix_phage	8.8e-30	37.4
WP_015051381.1\|2354382_2355636_-	DNA modification methylase	A0A2I4R670	Erysipelothrix_phage	1.2e-101	47.2
WP_015051382.1\|2355641_2356940_-	DNA modification methylase	A0A2I4R670	Erysipelothrix_phage	2.4e-76	40.0
WP_015051383.1\|2356914_2357097_-	hypothetical protein	NA	NA	NA	NA
WP_015051384.1\|2357096_2357648_-\|terminase	P27 family phage terminase small subunit	A0A2K5B277	Erysipelothrix_phage	6.3e-71	68.7
WP_081578670.1\|2358488_2358755_-\|transposase	transposase	NA	NA	NA	NA
WP_015051386.1\|2358703_2359387_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_015049906.1\|2359415_2359733_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_9

2405832 : 2459963

Wolbachia_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081578674.1\|2405832_2407503_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_028991316.1\|2407617_2407923_+	hypothetical protein	NA	NA	NA	NA
WP_049886129.1\|2407935_2409063_-	type 2 isopentenyl-diphosphate Delta-isomerase	NA	NA	NA	NA
WP_015051436.1\|2409127_2409403_-	4Fe-4S dicluster domain-containing protein	NA	NA	NA	NA
WP_015051437.1\|2409403_2409976_-	2-oxoacid:acceptor oxidoreductase family protein	NA	NA	NA	NA
WP_148276013.1\|2409979_2410711_-	2-oxoglutarate synthase	NA	NA	NA	NA
WP_015051439.1\|2410749_2411853_-	2-oxoglutarate synthase subunit KorA	NA	NA	NA	NA
WP_015051440.1\|2411960_2412557_-	UbiX family flavin prenyltransferase	NA	NA	NA	NA
WP_015051441.1\|2412611_2413526_-	DMT family transporter	NA	NA	NA	NA
WP_015051442.1\|2413727_2414990_-	TRAP transporter large permease subunit	NA	NA	NA	NA
WP_028991315.1\|2414974_2415532_-	TRAP transporter small permease	NA	NA	NA	NA
WP_148276014.1\|2415588_2416497_-	TRAP transporter substrate-binding protein DctP	NA	NA	NA	NA
WP_015051445.1\|2416792_2418136_-	UbiD family decarboxylase	NA	NA	NA	NA
WP_015051446.1\|2418205_2419399_-	4Fe-4S binding protein	NA	NA	NA	NA
WP_015051447.1\|2419604_2420258_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_015051448.1\|2420532_2420940_-	DUF126 domain-containing protein	NA	NA	NA	NA
WP_015051449.1\|2420936_2422157_-	DUF521 domain-containing protein	NA	NA	NA	NA
WP_015051450.1\|2422279_2422954_-	RraA family protein	NA	NA	NA	NA
WP_148276015.1\|2422987_2423623_-	4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase	NA	NA	NA	NA
WP_028991314.1\|2423672_2424344_-	RraA family protein	NA	NA	NA	NA
WP_015051453.1\|2424472_2426131_-	FAD-binding protein	M1I0Y3	Acanthocystis_turfacea_Chlorella_virus	3.8e-10	26.7
WP_015051454.1\|2426164_2427358_-	4Fe-4S binding protein	NA	NA	NA	NA
WP_148276016.1\|2428262_2428811_+	nucleotidyltransferase domain-containing protein	NA	NA	NA	NA
WP_015051456.1\|2428807_2429218_+	HEPN domain-containing protein	NA	NA	NA	NA
WP_015051457.1\|2429371_2429926_-	cytochrome c3	NA	NA	NA	NA
WP_015051458.1\|2429977_2431210_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_148276017.1\|2431430_2433125_-	FAD-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	2.6e-22	24.9
WP_015051460.1\|2433561_2433783_+	DUF378 domain-containing protein	NA	NA	NA	NA
WP_015051462.1\|2434149_2434449_-	hypothetical protein	NA	NA	NA	NA
WP_015051463.1\|2434441_2434999_-	ATP-binding protein	NA	NA	NA	NA
WP_015051464.1\|2435818_2436160_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_015051465.1\|2436159_2436408_-	hypothetical protein	NA	NA	NA	NA
WP_148275911.1\|2436557_2436800_+	hypothetical protein	NA	NA	NA	NA
WP_037999814.1\|2436950_2437226_+	BrnT family toxin	NA	NA	NA	NA
WP_148276018.1\|2437231_2437552_+	hypothetical protein	NA	NA	NA	NA
WP_015051468.1\|2437832_2438030_+	hypothetical protein	NA	NA	NA	NA
WP_015051469.1\|2438070_2438394_+\|transposase	transposase	NA	NA	NA	NA
WP_015051470.1\|2438417_2439062_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_015051471.1\|2440644_2441883_-\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	1.6e-53	41.7
WP_015051472.1\|2442275_2443490_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	2.7e-50	31.6
WP_081578676.1\|2446079_2447750_-\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_015051472.1\|2448405_2449620_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	2.7e-50	31.6
WP_015051475.1\|2452788_2453145_-	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	9.5e-20	43.8
WP_015049782.1\|2453138_2453459_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_081578676.1\|2458292_2459963_+\|transposase	IS1634 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_018870

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection