CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_018593	Listeria monocytogenes SLCC7179, complete genome	1 crisprs	DinG,cas3,WYL,RT,DEDDh,csa3	2	4	6	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_018593_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018593_1

506166-506389

Orphan

I-A

Consensus_repeat	Method
GTTTTAGTTACTTATTGTGAAATGTAAAT	PILER-CR
GTTTTAGTTACTTATTGTGAAATGTAAAT	CRT
TTTTAGTTACTTATTGTGAAATGTAAAT	CRISPRCasFinder

3 spacers

The CRISPR arrays of NC_018593_1

>merge|NC_018593|1|506166-506389|PILER-CR,CRT,CRISPRCasFinder
GTTTTAGTTACTTATTGTGAAATGTAAATTTTATTTCTCCTACGCTTTTCTTATTTCTGTAAATAAGTTTTAGTTACTTATTGTGAAATGTAAATCTAAAACATCCTTCACTGTATCAACTCCTTTCTATATTTTAGTTACTTATTGTGAAATGTAAATACAATAATAGGATATTTTGGATTTGTCTGCGTTCCTGTTTTAGTTACTTATTGTGAAATGTAAAT

>NC_018593|1|1|506166-506389|PILER-CR
GTTTTAGTTACTTATTGTGAAATGTAAAT	TTTATTTCTCCTACGCTTTTCTTATTTCTGTAAATAA
GTTTTAGTTACTTATTGTGAAATGTAAAT	CTAAAACATCCTTCACTGTATCAACTCCTTTCTAT
ATTTTAGTTACTTATTGTGAAATGTAAAT	ACAATAATAGGATATTTTGGATTTGTCTGCGTTCCT
GTTTTAGTTACTTATTGTGAAATGTAAAT

>NC_018593|1|1|506166-506389|CRT
GTTTTAGTTACTTATTGTGAAATGTAAAT	TTTATTTCTCCTACGCTTTTCTTATTTCTGTAAATAA
GTTTTAGTTACTTATTGTGAAATGTAAAT	CTAAAACATCCTTCACTGTATCAACTCCTTTCTAT
ATTTTAGTTACTTATTGTGAAATGTAAAT	ACAATAATAGGATATTTTGGATTTGTCTGCGTTCCT
GTTTTAGTTACTTATTGTGAAATGTAAAT

>NC_018593|1|1|506167-506389|CRISPRCasFinder
TTTTAGTTACTTATTGTGAAATGTAAAT	TTTATTTCTCCTACGCTTTTCTTATTTCTGTAAATAAG
TTTTAGTTACTTATTGTGAAATGTAAAT	CTAAAACATCCTTCACTGTATCAACTCCTTTCTATA
TTTTAGTTACTTATTGTGAAATGTAAAT	ACAATAATAGGATATTTTGGATTTGTCTGCGTTCCTG
TTTTAGTTACTTATTGTGAAATGTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_018593.1\|WP_009930754.1\|506782_507361_+\|hypothetical-protein	unknown	unknown	unknown
NC_018593.1\|WP_010989498.1\|497979_500040_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NC_018593.1\|WP_014931191.1\|502213_503260_+\|galactitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|176198
NC_018593.1\|WP_003727296.1\|515702_516071_-\|DUF1304-domain-containing-protein	unknown	unknown	gnl\|CDD\|226282
NC_018593.1\|WP_012951245.1\|501566_502217_+\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|223114
NC_018593.1\|WP_003733191.1\|500673_501141_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129
NC_018593.1\|WP_003721294.1\|503583_504855_+\|PTS-galactitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226298
NC_018593.1\|WP_003721293.1\|503275_503569_+\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99908
NC_018593.1\|WP_003733192.1\|500043_500646_+\|SIS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223865
NC_018593.1\|WP_003721303.1\|514606_515422_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NC_018593.1\|WP_014931194.1\|510647_512477_+\|LapB-repeat-containing-protein	unknown	unknown	gnl\|CDD\|380190
NC_018593.1\|WP_119732271.1\|508238_509377_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_018593.1\|WP_014931192.1\|504994_505930_+\|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl\|CDD\|234929
NC_018593.1\|WP_003721298.1\|509441_509801_-\|Lin0512-family-protein	unknown	unknown	gnl\|CDD\|131113
NC_018593.1\|WP_003721286.1\|497220_497871_+\|transaldolase	unknown	unknown	gnl\|CDD\|223254
NC_018593.1\|WP_003721297.1\|507468_508149_+\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|153212
NC_018593.1\|WP_014600551.1\|513055_514486_-\|CapA-family-protein	unknown	unknown	gnl\|CDD\|225399
NC_018593.1\|WP_003721290.1\|501157_501556_+\|hypothetical-protein	unknown	unknown	unknown
NC_018593.1\|WP_003721301.1\|512577_513009_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NC_018593.1\|WP_009932856.1\|509807_510266_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378956

Protein	Function_ID	Function_description	E-value
NC_018593.1\|WP_010989498.1\|497979_500040_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	5.36772e-80
NC_018593.1\|WP_014931191.1\|502213_503260_+\|galactitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|176198	cd08236, sugar_DH, NAD(P)-dependent sugar dehydrogenases. This group contains proteins identified as sorbitol dehydrogenases and other sugar dehydrogenases of the medium-chain dehydrogenase/reductase family (MDR), which includes zinc-dependent alcohol dehydrogenase and related proteins. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Related proteins include threonine dehydrogenase, formaldehyde dehydrogenase, and butanediol dehydrogenase. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Horse liver alcohol dehydrogenase is a dimeric enzyme and each subunit has two domains. The NAD binding domain is in a Rossmann fold and the catalytic domain contains a zinc ion to which substrates bind. There is a cleft between the domains that closes upon formation of the ternary complex.	0
NC_018593.1\|WP_003727296.1\|515702_516071_-\|DUF1304-domain-containing-protein	gnl\|CDD\|226282	COG3759, COG3759, Predicted membrane protein [Function unknown].	2.33548e-41
NC_018593.1\|WP_012951245.1\|501566_502217_+\|ribulose-phosphate-3-epimerase	gnl\|CDD\|223114	COG0036, Rpe, Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism].	8.25352e-108
NC_018593.1\|WP_003733191.1\|500673_501141_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	2.76446e-37
NC_018593.1\|WP_003721294.1\|503583_504855_+\|PTS-galactitol-transporter-subunit-IIC	gnl\|CDD\|226298	COG3775, GatC, Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism].	7.01085e-178
NC_018593.1\|WP_003721293.1\|503275_503569_+\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99908	cd05566, PTS_IIB_galactitol, PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain that are expressed on three distinct polypeptide chains, in contrast to other PTS sugar transporters. The three genes encoding these subunits (gatA, gatB, and gatC) comprise the gatCBA operon. Galactitol PTS permease takes up exogenous galactitol, releasing the phosphate ester into the cytoplasm in preparation for oxidation and further metabolism via a modified glycolytic pathway called the tagatose-6-phosphate glycolytic pathway. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include galactitol, chitobiose/lichenan, ascorbate, lactose, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	3.06007e-27
NC_018593.1\|WP_003733192.1\|500043_500646_+\|SIS-domain-containing-protein	gnl\|CDD\|223865	COG0794, GutQ, Predicted sugar phosphate isomerase involved in capsule formation [Cell envelope biogenesis, outer membrane].	1.15952e-75
NC_018593.1\|WP_003721303.1\|514606_515422_-\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	5.01016e-50
NC_018593.1\|WP_014931194.1\|510647_512477_+\|LapB-repeat-containing-protein	gnl\|CDD\|380190	NF033186, internalin_K, class 1 internalin InlK. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface-anchored proteins with an N-terminal signal peptide, leucine-rich repeats, and a C-terminal LPXTG processing and cell surface anchoring site. Members of this family are internalin K (InlK), a virulence factor. See articles PMID:17764999. for a general discussion of internalins, and PMID:21829365, PMID:22082958, and PMID:23958637 for more information about internalin K.	4.38337e-121
NC_018593.1\|WP_119732271.1\|508238_509377_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.60115e-39
NC_018593.1\|WP_014931192.1\|504994_505930_+\|ribose-phosphate-pyrophosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	1.99785e-153
NC_018593.1\|WP_003721298.1\|509441_509801_-\|Lin0512-family-protein	gnl\|CDD\|131113	TIGR02058, lin0512_fam, conserved hypothetical protein. This family consists of few members, broadly distributed. It occurs so far in several Firmicutes (twice in Oceanobacillus), one Cyanobacterium, one alpha Proteobacterium, and (with a long prefix) in plants. The function is unknown. The alignment includes a perfectly conserved motif GxGxDxHG near the N-terminus. [Hypothetical proteins, Conserved].	5.62162e-67
NC_018593.1\|WP_003721286.1\|497220_497871_+\|transaldolase	gnl\|CDD\|223254	COG0176, MipB, Transaldolase [Carbohydrate transport and metabolism].	1.40072e-62
NC_018593.1\|WP_003721297.1\|507468_508149_+\|type-1-glutamine-amidotransferase	gnl\|CDD\|153212	cd01741, GATase1_1, Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. This group contains a subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. GATase activity catalyses the transfer of ammonia from the amide side chain of glutamine to an acceptor substrate. Glutamine amidotransferases (GATase) includes the triad family of amidotransferases which have a conserved Cys-His-Glu catalytic triad in the glutaminase active site. In this subgroup this triad is conserved. GATase activity can be found in a range of biosynthetic enzymes, including: glutamine amidotransferase, formylglycinamide ribonucleotide, GMP synthetase , anthranilate synthase component II, glutamine-dependent carbamoyl phosphate synthase, cytidine triphosphate synthetase, gamma-glutamyl hydrolase, imidazole glycerol phosphate synthase and, cobyric acid synthase. Glutamine amidotransferase (GATase) domains can occur either as single polypeptides, as in glutamine amidotransferases, or as domains in a much larger multifunctional synthase protein, such as CPSase.	7.71833e-60
NC_018593.1\|WP_014600551.1\|513055_514486_-\|CapA-family-protein	gnl\|CDD\|225399	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane].	9.64038e-100
NC_018593.1\|WP_003721301.1\|512577_513009_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	4.03126e-27
NC_018593.1\|WP_009932856.1\|509807_510266_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|378956	pfam12802, MarR_2, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.	9.15558e-13

>NC_018593.1|WP_014931192.1|504994_505930_+|ribose-phosphate-pyrophosphokinase
MAGKMKLFSVTSERPLATKIADYLDIPLCEVELQKFSDGEVKINIEESIRGTNAYVVQSMNSNVNERLMELLIMVDALKRASVHSINIIMPYYGYARQDRKARSREPITAKLMANLIQRAGANRLITVDLHAAQIQGFFNIPIDHLSAIPLIGDYLIENYGEKDVVVVAPDHSGVVRARRIADRLNAPIAILNRKPRPHEDEIMSVIGDVKGKVAIVVDDIIDTGVRATTSADTLLEKGAVEVIACATHSVMAGNATERLQNSSIKEVITSDSIDLPEDKQFDKLTTISIGRILGRAIEGVQENRSLHPLF
>NC_018593.1|WP_003721294.1|503583_504855_+|PTS-galactitol-transporter-subunit-IIC
MDIILDFFKYIIGLGVTVMMPIIITILGVIFRKKISVAFKAGLTVGVGFVGLGVITSLMLTTITPVTKALVENYNFKLTATDIGWGVGSSLAWGTEVVPFVFVAIIATNILMIAFKWTKTMDVDIWNYWQPLFIASALYLTTGSMIIAVLSSIINMAIIFKIADWTQKDVEDVLGLEGISLPQIQTTGWALVGYPMNWLLGKIPGVRKINWSTEKVQSRLGIFGEPMLMGLIIGGGLAAIAQMPLSQVLQTGVTIAASLVLIPRMVSLLMDGLTVISEAAHEFMEKRFPGRELFIGLDSAVGIGHPFVLSLGLLMIPITLILAFILPGNKVLPLADLTALPFYMIFAIVPSKGNLFRGIFTGIVIVIITLYLSGAAAPLMTELAGQIGYNIPKDAVEVTSLAVGTQWYTWIVYYGLHWFGGIL
>NC_018593.1|WP_003721293.1|503275_503569_+|PTS-sugar-transporter-subunit-IIB
MKKKRIYVCCGTGIATSTVISKKVRAVLDEKRIPYEISQCTVQEVASKVSTSKPDIIVSSTTVTGDVGDVPVVIGRSFLTGLKKQETIDEILAILQD
>NC_018593.1|WP_014931191.1|502213_503260_+|galactitol-1-phosphate-5-dehydrogenase
MKALKLYGKRDLRYEEADMPTIEEPDDVILKVKTVGICGSDISRYSKLGPYVPGMVWGHEFSEEVIEVGSEVTDIEIGDRAAGCPALYCGECEYCKKGEFARCRKLTVIGARHPGAYAEYIKLPAENVVKIPNELDYEAAALVEPSAVVVHGFYHTKLQAGDDVVVVGSGNIGLLAIQWAKVFGARRVIAIDVDDKKLALAKEVGADVVINSLKEDPLEVVAAHTDGLNADLVVEAAGSPITSAQVFAYAKKGGGVVFLGIPYADVTIERFYFEKIVRSELTVWGSWNAISAPFPGKEWQTTIHFLANKQINIEPMITHRLSLAEGPEVFERIYERNEFFGKVLFFPE
>NC_018593.1|WP_012951245.1|501566_502217_+|ribulose-phosphate-3-epimerase
MAKIVPSVFGADIGRINEQLQVLEKNDIDLLHVDMMDGSFVPNIAFGPDQIKMMKKGTKLQFDVHMMVYEPDRYIPRLVEAGAHMITVHQEATTHLHRTIQLIKSYGVRAGVVLNPGTPPSTLEYVLDDIDCILLMTVNPGLGGQKFFQSSLEKIRKTKAYIGNRPIQIEVDGGVNAELAKECTLAGADLIVVGSYLFEGDIEANLEKLAKGVLTE
>NC_018593.1|WP_003721290.1|501157_501556_+|hypothetical-protein
MGSFFASFVDWLIGSPGRFVVNLIEDNMLIFMVVVMIYATTILYAKWTLAYYLPKKMSQLAEMKTWELDELYAAWQTEKKALPWYILVPSRNEFWVKSARNAPESTKLLHFSQQKLKLSDKEKLQKIIEIQS
>NC_018593.1|WP_003733191.1|500673_501141_+|PTS-sugar-transporter-subunit-IIA
MDVLEYFKEEMVRFSNEQNKEKLLAEMAEQLCEVGAVKPSYKDAVIKREKVFPTGLLTAHAGVAIPHTDSEHVIRPVVAVRILKKPVSFIEMASDNEAIDVRIVFMMALRSADEQLDMLQTLIQLIQDEEVMTTLLKAQETGDVLSAIEHFSKNN
>NC_018593.1|WP_003733192.1|500043_500646_+|SIS-domain-containing-protein
MDKQAILNNIHQTWQEEANAISRLPEVTSEEALVKTVEKIAECTGKIVVAGCGTSGVAAKKLVHSFNCIERPAVFLTPSDAVHGTLGVLQKEDILILISKGGNTGELLNLIPACKTKGSTLIGVTENPDSVIAKEADIFFPVSVSKEPDPFNMLATASTMAVIASFDAVIVCLMTYMNYTKEQFSVIHPGGAVGNKLLNK
>NC_018593.1|WP_010989498.1|497979_500040_+|BglG-family-transcription-antiterminator
MYLDNRSKTLFQEVIKNPNITNKQLEVKYKLSRYQISYSFQKVNEWLKWKNYPEVKRSKNGRFILEPELTALFSEKETRDPSVEYLPSENERANLILLMLLTSKEELSLAHFTTKIQVSKNTILRDLKVAQKLLPKETTVTYSRASGYQLAGSEWELRKVLTQVVSSVKEMFRGEHYFLSYSGIEKVQLMEIRRTLEEAEAMMQIKFTYEQIELLPYLLSVMFLRIRDRRLIDTAFHIDEKSLSDTREYHITDILLEKTGPVPEQERLFITLQLLTTNIFSGEILTEKLTEDLEKVVLTCLDLFEKKALVSLKNKHILIEKLLLHLKPAYYRIKYQMNLEDTLYEKFNQEFEALNFIVKEAFDPLAKFIGREIPAGEIFFISLFIGSDMIPQNDIYHKQKRAIVLCPSGVTFSKIMENILVKLFPEIHFYPTISVREYAFFKAEVDIVFSSIPLKDGENVFVVQPFMNDIEKTQLRQHVLQNLFGMGNQLTSIDKIMEVVERNADIKDPNAIRDGIIDILSANIATDENKRVKKVYLHDLITEDNIMICEDVKNYQEAIRLASQPLLLQQAITANYVKTMIDNHKFHDPYIIIGEDIAIPHAMPNAGVNRLAMSLLVVKNGVYFSETEQVHFVIVIAPVDKEQHIEALYQIVHLAENHQILDDLLENVTKEKIMQTINQLVIREDE
>NC_018593.1|WP_003721286.1|497220_497871_+|transaldolase
MHLDSANLDDVKKIQASSIFKGITTNPSILVKEKCNRQTAINRILELTDKQVFVQTVGFTYEEILADARMLLTMFGKDKIAIKIPAHEAGTNVIDTLKKEDKTIQILGTAIYSADQAITAALAGADFVAPYVNRMSAANIDPFKEISQMRHFFDKKALKTQIMAASFKHSGQVMQAYESGADTVTIPYEIYSQMTNKVLAVEAIRVFNEDAVLYEK
>NC_018593.1|WP_009930754.1|506782_507361_+|hypothetical-protein
MKKILVPILLLATILASCSSPNEKITKDTKISKTITIRADYKVPKDIKELEDDSANIVKVKFLQNKTIGKDGSTISEIEILTSYKGNLEKGSKVDISEPWYLSDGKYVAVENYIALDKEQEYTIFLGEKDKDTYPLSSLGYGKFGGSLKEDQAVLADFNILGEVQKFDFISENTEEVKNYQLIKEQVAGKYK
>NC_018593.1|WP_003721297.1|507468_508149_+|type-1-glutamine-amidotransferase
MIIDVLQHVPHEGPGLIANWARENQHQLKIHSLFEENAHVPNDSDFLIVLGGPMGINDTAEFPWLKDERKLIKRLSEQHKPVFGVCLGAQQIAATFGSEITVNKEKEVGWFPVKRTSDKLLFFPESLNVFHWHQDTFALPTGSTRLFASEGCLNQAFLYGENIIGLQFHFEMEKAGIETILRIDEAFITPGKYVQSVEVMREKDVPEDNKQMLEAILDYLINPKTI
>NC_018593.1|WP_119732271.1|508238_509377_+|IS3-family-transposase
MSTRVMYPAEIKEKAIKMKLAGKSTKEIMRTLNIKNPTQVKTWWRWYRNEETHRFHQGVGKQYKYQKGVPELPEIEQLKIALRQKELELEIFKKVQGIGKEVNPAYFVLLVEELKTKYLVKDICQILQVPLSTYYRWKKKDFAQSSLEKKIGQLCKTYQFTYGYRKIAALMKQEEQVGINKVQRIMQKYQWQCQVKVKKKNRPGSAYYQTENHLNRNFQASQPLEKLTTDITYLYFGDCRLYLSSIMDLYNGEIVAYSIGEKQDSELVLDTLNQLSLPEGSLLHSDQGSVYTSYEYFQCCKKKNVIRSMSRKGTPADNAPIECFHSSLKCETFYHKTAYKYAKSIVIQIVKDYIKYYNEKRIQQKLGYQSPINFRKQAA
>NC_018593.1|WP_003721298.1|509441_509801_-|Lin0512-family-protein
MEQILFIQTGFGVDVHGQNITKAAERAVRNAIFTNSMPGIQGLLPDGDLQNMVVNIKLALPCDADQLDEDTIRAIIPYGTVTIEKMAGGMMTTSGIFLEDKEDKNDLMYIVNASVETGY
>NC_018593.1|WP_009932856.1|509807_510266_-|MarR-family-transcriptional-regulator
MNNEQNMNQQIALFYFGYKAFTETADLIIAKHSLKRLHHRILFFTARMPGLTINELLTFLEISKQALHQPLAELKERELLTIEQGRRDKRQRCIFLTSAGKELENELGAAQRKQMSEIFTNSADTDGMHFTEVMEGYAKNRPGAAFIKDFKE
>NC_018593.1|WP_014931194.1|510647_512477_+|LapB-repeat-containing-protein
MKKALKLFLAMICMFIMIYPSTAAHAEETNIVNIPDANLKTYLNGLLKQASDAPITKTQMNTIQTVTLSGSTYTDLTGLEEAGNLVTLSINNTNIQTLEPIKNQTSLTYLTVGGDNVKDSLFVDLNGLVNLQSLSINGSEVTHNVFKTFNKLPKLTYLYAQNSMKITDISALASLPALTTLFLQFDGIDDFRPLNDFESFKNGNLKALAAFGQNTGRTNPRITLKSGKLDYNETNQTLYLPFSMMPKPLTSFDGTVAPFSKSTSASNTYLGFNDVALPSSRLSITDEGITVSGVTKEEFDNLDEIEYNARYDFPTGSYPTPPSMNSYTISSGTYDQYFDISHTLDLTADESFDYNQYDATSEEQFLKDIHAETDDGTAVQSDFDQVVKLDVPGEYTVTLNAENAAGLKATPVTVKVTVHEKPVITADSQISYKKESTKSVDEFLQEIHSSVTGNAVLTSDFDKVVDLNTPGEYTVTLHATNNRGQQADPVTVIVTVTASDGGHVNPIPPTPEVKPTPQEETDPTIIPEPQSENSEDQVKENNTKTEEKANKTSLTTKENKVEKADKAEKANQAKTKALPQTGDTNKTALPIAGVMLSLAALLIFRKSKS
>NC_018593.1|WP_003721301.1|512577_513009_+|universal-stress-protein
MEKYHRILVAVDGSEPAKLAFEKGLELALKLDGVLGIASIVDLRAFSPNVSYDGSLEEKAELELKTSVNEYAEKARTAGVKQVETFVAKGNPKILLSTDIPAEFQADLIICGATGMNRVEKLVLGSVSSYIMAHAICDTLIAR
>NC_018593.1|WP_014600551.1|513055_514486_-|CapA-family-protein
MKKLTYVIITGLVLVFIAGAFWITNSTNQSDQKATQTEPIKKISPANVKTISSEAKKTLNSLASSGADKASISDLKQLIKELKSYPTEKNDSGVYLQNLTACLEAVKSYTTGKTDEKTLGKVYPAFLASEQKLSAIEKTNQYDWFYAAAATNQQGLKEKGVVTLTMVGDNSFGTYPETPEHLKFDNVFQKNNGNNTYVYKNCLPWFKSDDYTVINAESAFTNATKAENKKWRIKSDPAHVAFLPASGVEAANLANNHTMDYFQVGYDDTLKAFKENNIPVFNTDAPLETTIKGMKTVLLGYDCRMSQQSPAYLERIVKDVKKYKKEDTLVIVNMHWGVEYRETPTDYQTQFGHAILDAGADIIMGSHPHRLESVEKYKDKYIVYSMGDFAFGADPTLLSRMTSMFQLRFTKEDNKIVLKDISIVPTYENSDGSTTENNYQPLPVFGDDAKKIVDELNRISKPIEGGVTEYTYFDPF
>NC_018593.1|WP_003721303.1|514606_515422_-|histidine-phosphatase-family-protein
MKKNIFKLLMALCAVLLIAGCGNSTSADKKETKETKEDGTVTFYVVRHGKTMLNTTDRVQGWSDAVLTPAGEEVVKSAGKGLKDVDFSAAYSSDSGRAIQTANLILKESDKSADKEVQTDPRFREFNFGSYEGDLNENMWTDIAKSQGKTLEEWQKAGLSPKDFANSVAALDKTRVKEGENWPAEDYATIQARLKEGLTDVAKKESKNGDSNVLLVSHGLSIGALLDTIEPGYKLPAEGIKNASVTKITYKDGKFTIGDVNDLSYVEKGSK
>NC_018593.1|WP_003727296.1|515702_516071_-|DUF1304-domain-containing-protein
MAILAFILTFIVMIEHIYIMILEMFFANTKLAAKTFGVEKELLANKKVQTLFANQGLYNGFLAAGLVWGLFFAGAGFAETVQIFFLSCVVVAALFGGATSSKGILVKQGLPAVLALVAVLLV

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_018593_1	1.2\|506261\|35\|NC_018593\|PILER-CR,CRT	506261-506295	35	NC_018593.1	2574083-2574117	2	0.943
NC_018593_1	1.5\|506261\|36\|NC_018593\|CRISPRCasFinder	506261-506296	36	NC_018593.1	2574082-2574117	2	0.944

1. spacer 1.2|506261|35|NC_018593|PILER-CR,CRT matches to position: 2574083-2574117, mismatch: 2, identity: 0.943

ctaaaacatccttcactgtatcaactcctttctat	CRISPR spacer
ctaacacatccttcactgtctcaactcctttctat	Protospacer
**** ************** ***************

2. spacer 1.5|506261|36|NC_018593|CRISPRCasFinder matches to position: 2574082-2574117, mismatch: 2, identity: 0.944

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaacacatccttcactgtctcaactcctttctata	Protospacer
**** ************** ****************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_018593_1	1.2\|506261\|35\|NC_018593\|PILER-CR,CRT	506261-506295	35	NC_021539	Listeria phage LP-030-2, complete genome	18926-18960	1	0.971
NC_018593_1	1.2\|506261\|35\|NC_018593\|PILER-CR,CRT	506261-506295	35	KJ094023	Listeria phage LP-101, complete genome	22882-22916	1	0.971
NC_018593_1	1.5\|506261\|36\|NC_018593\|CRISPRCasFinder	506261-506296	36	NC_021539	Listeria phage LP-030-2, complete genome	18926-18961	1	0.972
NC_018593_1	1.5\|506261\|36\|NC_018593\|CRISPRCasFinder	506261-506296	36	KJ094023	Listeria phage LP-101, complete genome	22882-22917	1	0.972
NC_018593_1	1.1\|506195\|37\|NC_018593\|PILER-CR,CRT	506195-506231	37	NC_009812	Listeria phage B025, complete genome	30705-30741	2	0.946
NC_018593_1	1.2\|506261\|35\|NC_018593\|PILER-CR,CRT	506261-506295	35	NC_009812	Listeria phage B025, complete genome	23381-23415	2	0.943
NC_018593_1	1.5\|506261\|36\|NC_018593\|CRISPRCasFinder	506261-506296	36	NC_009812	Listeria phage B025, complete genome	23381-23416	2	0.944
NC_018593_1	1.4\|506195\|38\|NC_018593\|CRISPRCasFinder	506195-506232	38	NC_009812	Listeria phage B025, complete genome	30704-30741	3	0.921

1. spacer 1.2|506261|35|NC_018593|PILER-CR,CRT matches to NC_021539 (Listeria phage LP-030-2, complete genome) position: , mismatch: 1, identity: 0.971

ctaaaacatccttcactgtatcaactcctttctat	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctat	Protospacer
******************* ***************

2. spacer 1.2|506261|35|NC_018593|PILER-CR,CRT matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 1, identity: 0.971

ctaaaacatccttcactgtatcaactcctttctat	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctat	Protospacer
******************* ***************

3. spacer 1.5|506261|36|NC_018593|CRISPRCasFinder matches to NC_021539 (Listeria phage LP-030-2, complete genome) position: , mismatch: 1, identity: 0.972

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctata	Protospacer
******************* ****************

4. spacer 1.5|506261|36|NC_018593|CRISPRCasFinder matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 1, identity: 0.972

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctata	Protospacer
******************* ****************

5. spacer 1.1|506195|37|NC_018593|PILER-CR,CRT matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.946

tttatttctcctacgcttttcttatttctgtaaataa	CRISPR spacer
tttatttctcctgcgcttttcttatttttgtaaataa	Protospacer
************.**************.*********

6. spacer 1.2|506261|35|NC_018593|PILER-CR,CRT matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.943

ctaaaacatccttcactgtatcaactcctttctat	CRISPR spacer
ctaaaacatccttcactatctcaactcctttctat	Protospacer
*****************.* ***************

7. spacer 1.5|506261|36|NC_018593|CRISPRCasFinder matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.944

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaaaacatccttcactatctcaactcctttctata	Protospacer
*****************.* ****************

8. spacer 1.4|506195|38|NC_018593|CRISPRCasFinder matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 3, identity: 0.921

tttatttctcctacgcttttcttatttctgtaaataag	CRISPR spacer
tttatttctcctgcgcttttcttatttttgtaaataaa	Protospacer
************.**************.*********.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

120252 : 126777

Listeria_phage(33.33%)

tail

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003721739.1\|120252_120705_-	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	4.0e-31	47.9
WP_003721740.1\|120710_121046_-	helix-turn-helix transcriptional regulator	A0A2H4JAR9	uncultured_Caudovirales_phage	4.0e-20	52.5
WP_003732219.1\|121262_121691_+	hypothetical protein	NA	NA	NA	NA
WP_014931069.1\|121702_122119_+	hypothetical protein	A8ASQ1	Listeria_phage	7.7e-21	39.3
WP_012952083.1\|122396_122786_+	DUF5072 family protein	NA	NA	NA	NA
WP_003721744.1\|122798_123311_+\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	1.2e-47	62.7
WP_003721745.1\|123358_123661_+	hypothetical protein	NA	NA	NA	NA
WP_014601581.1\|123702_124107_+	hypothetical protein	NA	NA	NA	NA
WP_014931070.1\|124093_125962_+	membrane protein	A0A097PAU2	Streptococcus_pyogenes_phage	3.5e-20	45.8
WP_003734720.1\|125958_126777_+\|tail	phage tail family protein	A0A060AFE1	Staphylococcus_phage	7.2e-39	35.0

DBSCAN-SWA_2

1086733 : 1094155

Hokovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003721506.1\|1086733_1087117_+	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	1.4e-16	40.7
WP_003732709.1\|1087138_1088122_+	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	4.1e-12	34.6
WP_014931338.1\|1088136_1089150_+	glycosyltransferase	A0A1V0SAH6	Catovirus	7.9e-11	32.0
WP_014931339.1\|1089358_1090849_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	7.3e-114	49.7
WP_014931340.1\|1090860_1091685_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	4.8e-67	52.4
WP_014931341.1\|1091697_1092006_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_014931342.1\|1092065_1092470_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_014931343.1\|1092598_1094155_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	2.3e-17	28.1

DBSCAN-SWA_3

1232259 : 1291740

Bacillus_virus(16.67%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003723562.1\|1232259_1233399_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_014931390.1\|1233479_1233875_-	helix-turn-helix transcriptional regulator	A9D9J6	Lactobacillus_prophage	1.3e-14	57.4
WP_003727524.1\|1234025_1234241_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014931391.1\|1234359_1234893_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_003732795.1\|1234910_1235576_+	hypothetical protein	NA	NA	NA	NA
WP_003732796.1\|1235837_1236776_+	hypothetical protein	NA	NA	NA	NA
WP_003723884.1\|1236890_1238174_+	trigger factor	NA	NA	NA	NA
WP_003723886.1\|1238358_1239618_+\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-145	63.2
WP_009924620.1\|1239736_1240303_+	type I signal peptidase SipX	NA	NA	NA	NA
WP_003723888.1\|1240337_1240907_+	type I signal peptidase SipY	NA	NA	NA	NA
WP_003723889.1\|1241008_1241551_+	type I signal peptidase SipZ	NA	NA	NA	NA
WP_003723890.1\|1241560_1242424_+	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_003723891.1\|1242420_1243206_+	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	3.0e-26	39.2
WP_014931392.1\|1243339_1244200_+	DNA-protecting protein DprA	NA	NA	NA	NA
WP_003732799.1\|1244471_1246550_+	type I DNA topoisomerase	A0A1V0SB35	Catovirus	3.2e-107	37.5
WP_009924616.1\|1246612_1247917_+\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
WP_009911635.1\|1248199_1249102_+	tyrosine recombinase XerC	A0A097EYL9	Mycobacterium_phage	1.2e-13	28.6
WP_003724001.1\|1249122_1249662_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_012581410.1\|1249675_1251085_+\|protease	ATP-dependent protease ATPase subunit HslU	W6AS21	Erwinia_phage	5.8e-44	28.8
WP_003726695.1\|1251105_1251885_+	GTP-sensing pleiotropic transcriptional regulator CodY	NA	NA	NA	NA
WP_014931393.1\|1251987_1252407_+	acyl-CoA thioesterase	NA	NA	NA	NA
WP_003724130.1\|1252429_1252741_+	hypothetical protein	NA	NA	NA	NA
WP_009932949.1\|1252743_1253616_+	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_003724132.1\|1253657_1254254_-	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_003732802.1\|1254411_1254819_+	CoA-binding protein	NA	NA	NA	NA
WP_003723731.1\|1254999_1256967_+	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	6.7e-123	42.5
WP_010989723.1\|1256963_1259423_+	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	4.7e-102	31.6
WP_003723733.1\|1259505_1259973_+	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_014931394.1\|1260302_1262072_+	lmo1289 family class 1 internalin	NA	NA	NA	NA
WP_014931395.1\|1262404_1264201_+	class 1 internalin InlK	NA	NA	NA	NA
WP_012951576.1\|1264234_1266103_-	peptidoglycan O-acetyltransferase OatA	B5WZU0	Pseudomonas_phage	6.5e-43	31.9
WP_003723737.1\|1266315_1267014_+	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	1.3e-12	32.4
WP_003723738.1\|1267246_1268923_+	glycerol-3-phosphate dehydrogenase/oxidase	NA	NA	NA	NA
WP_012951578.1\|1269048_1269966_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_003719566.1\|1270088_1270322_+	RNA chaperone Hfq	NA	NA	NA	NA
WP_077906793.1\|1270432_1271656_+	GTPase HflX	NA	NA	NA	NA
WP_014931397.1\|1271648_1272875_+	methionine gamma-lyase family protein	NA	NA	NA	NA
WP_003719570.1\|1273078_1273447_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_003723435.1\|1273517_1274852_+	type I glutamate--ammonia ligase	A0A1V0SJ53	Klosneuvirus	2.0e-06	26.4
WP_012951579.1\|1274995_1276291_+	arsenic transporter	A0A2H4PQU3	Staphylococcus_phage	2.8e-146	61.9
WP_003723437.1\|1276334_1276856_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003723438.1\|1276885_1277500_-	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	9.3e-15	62.1
WP_003723439.1\|1277657_1277987_+	cell division suppressor protein YneA	NA	NA	NA	NA
WP_003723440.1\|1278078_1278306_+	DUF896 domain-containing protein	NA	NA	NA	NA
WP_003732809.1\|1278452_1280447_+	transketolase	NA	NA	NA	NA
WP_003723442.1\|1280667_1280907_+	YneF family protein	NA	NA	NA	NA
WP_003723443.1\|1280957_1281800_-	DUF2785 domain-containing protein	NA	NA	NA	NA
WP_003723444.1\|1281818_1282550_-	methyltransferase domain-containing protein	A0A1X9I6N4	Streptococcus_phage	1.2e-80	59.1
WP_003723445.1\|1282571_1283078_-	ParB-like nuclease domain-containing protein	A0A220GKT8	Streptococcus_phage	4.0e-56	66.7
WP_014931398.1\|1283087_1284392_-	DUF3440 domain-containing protein	A0A220GKF8	Streptococcus_phage	9.5e-134	52.1
WP_077906794.1\|1284381_1285587_-	helicase SNF2	L0P6E9	Lactobacillus_phage	4.9e-92	47.1
WP_003723448.1\|1285564_1285939_-	hypothetical protein	NA	NA	NA	NA
WP_003723449.1\|1286231_1286960_+	UMP kinase	NA	NA	NA	NA
WP_003723450.1\|1286959_1287517_+	ribosome recycling factor	NA	NA	NA	NA
WP_039385819.1\|1287746_1288505_+	isoprenyl transferase	R9W0U9	Flavobacterium_phage	7.4e-22	41.4
WP_003727496.1\|1288518_1289307_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_014931401.1\|1289321_1290464_+	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_003723454.1\|1290477_1291740_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA

DBSCAN-SWA_4

1781318 : 1789604

Prochlorococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014931513.1\|1781318_1781885_-	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	7.5e-27	39.1
WP_014931514.1\|1781881_1782931_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.2e-63	44.1
WP_003722245.1\|1782949_1784377_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-53	34.6
WP_014931515.1\|1784361_1786581_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.9e-158	41.1
WP_003733240.1\|1786573_1787257_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003722248.1\|1787260_1787506_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_014931516.1\|1787517_1788231_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	8.8e-41	37.8
WP_003729814.1\|1788311_1789604_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.5e-17	33.0

DBSCAN-SWA_5

2447179 : 2455023

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003722604.1\|2447179_2448151_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	5.2e-52	39.4
WP_014931662.1\|2448158_2449127_-	YvcK family protein	A1IMD5	Streptococcus_phage	8.8e-68	42.9
WP_010990001.1\|2449128_2450004_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	3.2e-08	29.7
WP_014601136.1\|2450111_2451842_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	4.3e-174	53.3
WP_026750232.1\|2451883_2452945_-	galactose mutarotase	NA	NA	NA	NA
WP_014931663.1\|2452961_2453945_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	1.7e-50	36.9
WP_003722610.1\|2454063_2455023_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.0e-88	53.7

DBSCAN-SWA_6

2541483 : 2625901

Listeria_phage(75.93%)

integrase,portal,plate,terminase,protease,tail,holin,tRNA,capsid

attL 2573315:2573364|attR 2612518:2612567

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003723609.1\|2541483_2543154_-\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
WP_003723610.1\|2543150_2543600_-	DUF1934 domain-containing protein	NA	NA	NA	NA
WP_003723611.1\|2543677_2544331_-\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_003723612.1\|2544405_2544591_+	4-oxalocrotonate tautomerase	NA	NA	NA	NA
WP_009924630.1\|2544625_2545948_-	HD domain-containing protein	A0A1B1ISR1	uncultured_Mediterranean_phage	2.6e-30	33.2
WP_009924631.1\|2545962_2546799_-	lipoyl-[GcvH]:protein N-lipoyltransferase	NA	NA	NA	NA
WP_003729274.1\|2547116_2547317_-	hypothetical protein	NA	NA	NA	NA
WP_003723616.1\|2547338_2547662_-	YxeA family protein	NA	NA	NA	NA
WP_014931674.1\|2547816_2549478_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003726112.1\|2549613_2550228_-	SdpI family protein	NA	NA	NA	NA
WP_014931675.1\|2550251_2550884_-	nicotinamidase	NA	NA	NA	NA
WP_003723621.1\|2550884_2551409_-	dihydrofolate reductase	NA	NA	NA	NA
WP_012952036.1\|2551411_2552410_-	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_014931676.1\|2552506_2552779_-	hypothetical protein	NA	NA	NA	NA
WP_003723624.1\|2552827_2553739_-	cation transporter	NA	NA	NA	NA
WP_014931677.1\|2553864_2558457_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_003733264.1\|2558677_2559505_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_014931678.1\|2559619_2560495_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_003723278.1\|2560505_2560799_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_012952039.1\|2560831_2560993_-	hypothetical protein	NA	NA	NA	NA
WP_003723280.1\|2561061_2561730_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.0e-38	42.0
WP_010990019.1\|2561729_2562818_-	ABC transporter permease	NA	NA	NA	NA
WP_014931679.1\|2562896_2564276_-	HAMP domain-containing sensor histidine kinase	W8CYF6	Bacillus_phage	1.4e-55	43.7
WP_003723283.1\|2564272_2564950_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.6e-58	48.4
WP_014931680.1\|2564996_2565782_-	formate dehydrogenase accessory sulfurtransferase FdhD	NA	NA	NA	NA
WP_003723285.1\|2565843_2566320_-	DUF1641 domain-containing protein	NA	NA	NA	NA
WP_014931681.1\|2566319_2569307_-	formate dehydrogenase subunit alpha	NA	NA	NA	NA
WP_009931305.1\|2569805_2570648_+	S-adenosyl-l-methionine hydroxide adenosyltransferase family protein	NA	NA	NA	NA
WP_003733258.1\|2570695_2572177_-	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_003723289.1\|2572277_2573165_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
2573315:2573364	attL	NA	NA	NA	NA
WP_014931683.1\|2573734_2573968_-	hypothetical protein	A0A059T6E1	Listeria_phage	5.2e-35	94.8
WP_014931684.1\|2574405_2574591_+	hypothetical protein	R4IBK5	Listeria_phage	9.2e-19	86.7
WP_014931685.1\|2574660_2575398_+	hypothetical protein	NA	NA	NA	NA
WP_003734112.1\|2575513_2576359_-	M15 family metallopeptidase	A0A059T7Y8	Listeria_phage	2.0e-137	89.4
WP_003722522.1\|2576358_2576640_-\|holin	holin	A8ASL4	Listeria_phage	3.4e-41	94.6
WP_003722523.1\|2576652_2577018_-	hypothetical protein	Q9T1A0	Listeria_phage	7.4e-12	100.0
WP_003734113.1\|2577046_2577205_-	hypothetical protein	Q9T1A1	Listeria_phage	3.0e-18	98.1
WP_003727798.1\|2577209_2577527_-	hypothetical protein	Q9T1A2	Listeria_phage	1.3e-49	92.4
WP_014931686.1\|2577538_2578612_-\|plate	phage baseplate upper protein	Q9T1A3	Listeria_phage	7.4e-193	96.9
WP_014931687.1\|2578611_2579640_-	hypothetical protein	Q9T1A4	Listeria_phage	2.1e-189	98.8
WP_014931688.1\|2579640_2580666_-\|tail	phage tail protein	Q9T1A5	Listeria_phage	1.6e-192	94.7
WP_014931689.1\|2580674_2581493_-\|tail	phage tail family protein	Q9T1A6	Listeria_phage	7.2e-148	93.4
WP_014931690.1\|2581494_2586858_-	tape measure protein	Q9T1A7	Listeria_phage	0.0e+00	82.4
WP_003731740.1\|2586868_2587471_-	hypothetical protein	A8ASK5	Listeria_phage	2.0e-107	98.0
WP_003731739.1\|2587476_2587899_-\|tail	phage tail assembly chaperone	Q9T1A9	Listeria_phage	3.4e-69	98.6
WP_003731738.1\|2587950_2588283_-	Ig domain-containing protein	Q9T1B0	Listeria_phage	1.3e-39	84.5
WP_014931692.1\|2588212_2588650_-	hypothetical protein	A8ASK2	Listeria_phage	2.1e-77	98.6
WP_014931693.1\|2588652_2589060_-	hypothetical protein	A8ASK1	Listeria_phage	6.5e-65	97.8
WP_014931694.1\|2589059_2589398_-	hypothetical protein	A0A059T7W4	Listeria_phage	1.6e-56	96.4
WP_014931695.1\|2589397_2589760_-	hypothetical protein	A8ASJ9	Listeria_phage	1.0e-61	95.0
WP_003731735.1\|2589759_2590155_-	hypothetical protein	A8ASJ8	Listeria_phage	3.3e-66	99.2
WP_003731734.1\|2590156_2590315_-	hypothetical protein	Q9T1B6	Listeria_phage	6.7e-18	94.2
WP_014931696.1\|2590314_2591214_-\|capsid	phage major capsid protein	A0A0B5CU19	Listeria_phage	3.8e-166	98.7
WP_003759694.1\|2591237_2591807_-	phage scaffolding protein	Q9T1B8	Listeria_phage	1.1e-89	96.8
WP_014931697.1\|2591885_2593025_-\|capsid	phage minor capsid protein	Q9T1B9	Listeria_phage	4.4e-204	97.1
WP_003731730.1\|2593025_2594795_-\|portal	phage portal protein	A8ASJ3	Listeria_phage	2.0e-264	91.6
WP_014931698.1\|2594807_2596118_-\|terminase	PBSX family phage terminase large subunit	A0A286QNX6	Streptococcus_phage	1.5e-166	65.3
WP_014931699.1\|2596110_2596866_-\|terminase	terminase small subunit	V5URT8	Oenococcus_phage	9.0e-44	45.6
WP_041176806.1\|2596911_2597451_-	hypothetical protein	NA	NA	NA	NA
WP_003734123.1\|2597710_2598145_-	hypothetical protein	A8AU03	Listeria_phage	9.0e-73	95.1
WP_003734124.1\|2598163_2598328_-	hypothetical protein	A8ASQ0	Listeria_phage	6.7e-21	96.3
WP_014931701.1\|2598457_2598862_-	endodeoxyribonuclease	A8AU00	Listeria_phage	2.1e-71	99.3
WP_014601286.1\|2598827_2598968_-	BH0509 family protein	A8ATZ9	Listeria_phage	2.6e-18	100.0
WP_014601287.1\|2598964_2599270_-	hypothetical protein	A8ATZ8	Listeria_phage	1.5e-45	98.0
WP_014931702.1\|2599297_2599675_-	hypothetical protein	NA	NA	NA	NA
WP_014601288.1\|2599696_2600179_-	single-stranded DNA-binding protein	A8ATZ7	Listeria_phage	2.7e-78	93.1
WP_014931703.1\|2600175_2600376_-	hypothetical protein	NA	NA	NA	NA
WP_014931704.1\|2600668_2601229_-	pentapeptide repeat-containing protein	A0A060AFJ6	Listeria_phage	2.1e-29	69.4
WP_014931705.1\|2601246_2601786_-	DUF1642 domain-containing protein	A0A0B5D0I5	Listeria_phage	3.6e-95	92.2
WP_041176811.1\|2602606_2603137_-	hypothetical protein	A0A059T5F9	Listeria_phage	1.6e-95	94.9
WP_014931708.1\|2603184_2604111_-	hypothetical protein	I1W658	Staphylococcus_phage	6.7e-17	39.3
WP_014931709.1\|2604130_2604940_-	PD-(D/E)XK nuclease-like domain-containing protein	A0A290GJV0	Caldibacillus_phage	2.7e-78	54.3
WP_003753535.1\|2604893_2605775_-	hypothetical protein	A0A2P1JTZ5	Anoxybacillus_phage	3.4e-87	58.6
WP_003727754.1\|2605771_2605975_-	hypothetical protein	NA	NA	NA	NA
WP_014931710.1\|2606192_2606381_-	hypothetical protein	A0A0B5CU43	Listeria_phage	4.2e-27	93.5
WP_014931711.1\|2606483_2606690_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014931712.1\|2606679_2607210_-	hypothetical protein	A8ATY1	Listeria_phage	1.9e-77	87.3
WP_014931713.1\|2607330_2608119_-	phage antirepressor Ant	Q9T178	Listeria_phage	1.4e-135	93.1
WP_014931714.1\|2608131_2608407_-	hypothetical protein	A8ASM5	Listeria_phage	4.9e-40	85.1
WP_014931715.1\|2608432_2608717_-	hypothetical protein	A0A0B5D168	Listeria_phage	7.0e-42	87.2
WP_014931716.1\|2608781_2609141_+	DUF2513 domain-containing protein	A0A2H4J4K9	uncultured_Caudovirales_phage	2.1e-06	26.3
WP_003733687.1\|2609099_2609294_-	hypothetical protein	A0A059T6E5	Listeria_phage	1.4e-25	95.3
WP_003731437.1\|2609326_2609530_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014931717.1\|2609698_2610175_+	helix-turn-helix transcriptional regulator	A8ASM2	Listeria_phage	5.8e-41	62.7
WP_014601103.1\|2610332_2610500_+	hypothetical protein	NA	NA	NA	NA
WP_003731435.1\|2610554_2611205_+	hypothetical protein	NA	NA	NA	NA
WP_014931718.1\|2611266_2612430_+\|integrase	site-specific integrase	S5MNZ2	Brevibacillus_phage	1.2e-50	31.2
WP_003733022.1\|2618159_2619188_-	Mrp/NBP35 family ATP-binding protein	NA	NA	NA	NA
2612518:2612567	attR	NA	NA	NA	NA
WP_003733023.1\|2619456_2620983_+	GW domain-containing glycosaminoglycan-binding protein	A0A0K2CP65	Brevibacillus_phage	9.1e-27	48.7
WP_014931719.1\|2621024_2621876_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.0e-48	38.0
WP_014931720.1\|2621897_2622320_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_014602248.1\|2622441_2622801_-	hypothetical protein	NA	NA	NA	NA
WP_014931721.1\|2623044_2623914_+	DUF4969 domain-containing protein	NA	NA	NA	NA
WP_003723652.1\|2624108_2624501_-	30S ribosomal protein S9	NA	NA	NA	NA
WP_003727703.1\|2624522_2624960_-	50S ribosomal protein L13	NA	NA	NA	NA
WP_003733032.1\|2625154_2625901_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NC_018593.1|WP_003733687.1|2609099_2609294_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_018593.1|WP_003733687.1|2609099_2609294_-|hypothetical-protein

2609099_2609294_-

64 aa aa

HTH_XRE

Identity	Hit_domain_coverage
0.46551724137931033	1.0

2541483-2625901

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_018593_1	Orphan	1.2\|506261\|35\|NC_018593\|PILER-CR,CRT	506261-506295	35	2574117-2574083	2
NC_018593_1	Orphan	1.5\|506261\|36\|NC_018593\|CRISPRCasFinder	506261-506296	36	2574117-2574082	2

1. spacer 1.2|506261|35|NC_018593|PILER-CR,CRT matches to NC_018593 position: 2574117-2574083, mismatch: 2

ctaaaacatccttcactgtatcaactcctttctat	CRISPR spacer
ctaacacatccttcactgtctcaactcctttctat	Protospacer
**** ************** ***************

2. spacer 1.5|506261|36|NC_018593|CRISPRCasFinder matches to NC_018593 position: 2574117-2574082, mismatch: 2

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaacacatccttcactgtctcaactcctttctata	Protospacer
**** ************** ****************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_018593

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information