CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_019679	Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence	1 crisprs	NA	0	7	0	0
NC_019678	Rivularia sp. PCC 7116, complete genome	38 crisprs	DEDDh,WYL,cas3,cas10d,csc2gr7,csc1gr5,cas6,cas4,cas1,cas2,csa3,PD-DExK,c2c9_V-U4,DinG,cas14k,Cas14c_CAS-V-F,cas8b3,cas7,cas5,RT,cas10,csm3gr7,csx10gr5,csm2gr11,csx19,csx21,cas14j,csx3,cmr3gr5,cmr4gr7,cmr5gr11,csm6,2OG_CAS	3	40	5	0
NC_019686	Rivularia sp. PCC 7116 plasmid pRIV7116.02, complete sequence	0 crisprs	NA	0	0	0	0

1. NC_019679

CRISPR-Cas detection and classification

Crispr_ID: NC_019679_1

• CRISPR_ID: NC_019679_1
• CRISPR_location: 21556-22094
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 7 spacers

Consensus repeat of NC_019679_1

Consensus_repeat	Method
CTTTACTAACCCCT-AATCCCTAATAGGG----------ATGGAAAC	PILER-CR
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	CRISPRCasFinder
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	CRT

spacers of NC_019679_1

>1.1|21592|35|NC_019679|PILER-CR,CRISPRCasFinder,CRT
TTCTCTGTCCATCTGGACATTGAGAAAATCTCCAA
>1.2|21663|32|NC_019679|PILER-CR,CRISPRCasFinder,CRT
CGTATCTCCTGCTAAAGCTGGAATTGCTGAAG
>1.3|21731|36|NC_019679|PILER-CR,CRISPRCasFinder,CRT
ATAAATTTTCCCTATTGTCAAGTATTCACTAGGATG
>1.4|21803|39|NC_019679|PILER-CR,CRISPRCasFinder,CRT
AATCCGAAGGAACTCTAACTGTATTTGTTCCAGAAAACG
>1.5|21878|37|NC_019679|PILER-CR,CRISPRCasFinder,CRT
TAATAATTATTTTGTCTCTTTATCTCTACGTAAGTTC
>1.6|21951|37|NC_019679|PILER-CR,CRISPRCasFinder,CRT
TCAATAGTTTCGGTTATTGGTTCAAAAATATATTCGA
>1.7|22024|35|NC_019679|PILER-CR,CRISPRCasFinder,CRT
ATACTATAGCCTTTCTCAGTTTGAAACATTAACAT

CRISPR arrays and Neighbor proteins around NC_019679_1

CRISPR arrays

The CRISPR arrays of NC_019679_1

>merge|NC_019679|1|21556-22094|PILER-CR,CRISPRCasFinder,CRT
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAACTTCTCTGTCCATCTGGACATTGAGAAAATCTCCAACTTTACTAACCCCTAATCCCTAATAGGGATGGAAACCGTATCTCCTGCTAAAGCTGGAATTGCTGAAGCTTTACTAACCCCTAATCCCTAATAGGGATGGAAACATAAATTTTCCCTATTGTCAAGTATTCACTAGGATGCTTTACTAACCCCTAATCCCTAATAGGGATGGAAACAATCCGAAGGAACTCTAACTGTATTTGTTCCAGAAAACGCTTTACTAACCCCTAATCCCTAATAGGGATGGAAACTAATAATTATTTTGTCTCTTTATCTCTACGTAAGTTCCTTTACTAACCCCTAATCCCTAATAGGGATGGAAACTCAATAGTTTCGGTTATTGGTTCAAAAATATATTCGACTTTACTAACCCCTAATCCCTAATAGGGATGGAAACATACTATAGCCTTTCTCAGTTTGAAACATTAACATCTTTACTAACCCCTAATCCCTAATAGGGATTGAAAA

>NC_019679|1|1|21556-22094|PILER-CR
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	TTCTCTGTCCATCTGGACATTGAGAAAATCTCCAA
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	CGTATCTCCTGCTAAAGCTGGAATTGCTGAAG
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	ATAAATTTTCCCTATTGTCAAGTATTCACTAGGATG
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	AATCCGAAGGAACTCTAACTGTATTTGTTCCAGAAAACG
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	TAATAATTATTTTGTCTCTTTATCTCTACGTAAGTTC
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	TCAATAGTTTCGGTTATTGGTTCAAAAATATATTCGA
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	ATACTATAGCCTTTCTCAGTTTGAAACATTAACAT
CTTTACTAACCCCTAATCCCTAATAGGGATTGAAAA

>NC_019679|1|1|21556-22094|CRISPRCasFinder
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	TTCTCTGTCCATCTGGACATTGAGAAAATCTCCAA
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	CGTATCTCCTGCTAAAGCTGGAATTGCTGAAG
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	ATAAATTTTCCCTATTGTCAAGTATTCACTAGGATG
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	AATCCGAAGGAACTCTAACTGTATTTGTTCCAGAAAACG
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	TAATAATTATTTTGTCTCTTTATCTCTACGTAAGTTC
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	TCAATAGTTTCGGTTATTGGTTCAAAAATATATTCGA
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	ATACTATAGCCTTTCTCAGTTTGAAACATTAACAT
CTTTACTAACCCCTAATCCCTAATAGGGATTGAAAA

>NC_019679|1|1|21556-22094|CRT
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	TTCTCTGTCCATCTGGACATTGAGAAAATCTCCAA
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	CGTATCTCCTGCTAAAGCTGGAATTGCTGAAG
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	ATAAATTTTCCCTATTGTCAAGTATTCACTAGGATG
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	AATCCGAAGGAACTCTAACTGTATTTGTTCCAGAAAACG
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	TAATAATTATTTTGTCTCTTTATCTCTACGTAAGTTC
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	TCAATAGTTTCGGTTATTGGTTCAAAAATATATTCGA
CTTTACTAACCCCTAATCCCTAATAGGGATGGAAAC	ATACTATAGCCTTTCTCAGTTTGAAACATTAACAT
CTTTACTAACCCCTAATCCCTAATAGGGATTGAAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019679.1|WP_015122800.1|20537_20777_-|hypothetical-protein	unknown	unknown	unknown
NC_019679.1|WP_015122801.1|20766_21024_-|hypothetical-protein	unknown	unknown	unknown
NC_019679.1|WP_015122803.1|22776_24003_-|hypothetical-protein	unknown	unknown	gnl|CDD|212669
NC_019679.1|WP_015122797.1|17733_19626_-|hypothetical-protein	unknown	unknown	gnl|CDD|374724
NC_019679.1|WP_015122802.1|22194_22683_-|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl|CDD|378444
NC_019679.1|WP_015122793.1|14329_14821_-|hypothetical-protein	unknown	unknown	unknown
NC_019679.1|WP_015122804.1|24495_26826_-|hypothetical-protein	unknown	unknown	gnl|CDD|224117
NC_019679.1|WP_157229502.1|15610_17131_-|Terminase-like-family-protein	unknown	unknown	gnl|CDD|222858
NC_019679.1|WP_044292677.1|20255_20516_-|hypothetical-protein	unknown	unknown	unknown
NC_019679.1|WP_015122794.1|14823_15618_-|hypothetical-protein	unknown	unknown	unknown
NC_019679.1|WP_015122792.1|13925_14282_+|hypothetical-protein	unknown	unknown	unknown
NC_019679.1|WP_015122796.1|17140_17731_-|hypothetical-protein	unknown	unknown	unknown
NC_019679.1|WP_015122798.1|19680_20136_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019679.1|WP_015122804.1|24495_26826_-|hypothetical-protein	gnl|CDD|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	2.44454e-07
NC_019679.1|WP_015122802.1|22194_22683_-|GIY-YIG-nuclease-family-protein	gnl|CDD|378444	pfam10544, T5orf172, T5orf172 domain. This domain was identified by Iyer and colleagues.	1.3446e-09
NC_019679.1|WP_015122797.1|17733_19626_-|hypothetical-protein	gnl|CDD|374724	pfam16684, Telomere_res, Telomere resolvase. Telomere resolvase (protelomerase) catalyzes the conversion of linear double-stranded DNA into hairpin telomeres.	3.56702e-06
NC_019679.1|WP_157229502.1|15610_17131_-|Terminase-like-family-protein	gnl|CDD|222858	PHA02533, 17, large terminase protein; Provisional.	3.34429e-13
NC_019679.1|WP_015122803.1|22776_24003_-|hypothetical-protein	gnl|CDD|212669	cd10227, ParM_like, Plasmid segregation protein ParM and similar proteins. ParM is a plasmid-encoded bacterial homolog of actin, which polymerizes into filaments similar to F-actin, and plays a vital role in plasmid segregation. ParM filaments segregate plasmids paired at midcell into the individual daughter cells. This subfamily also contains Thermoplasma acidophilum Ta0583, an active ATPase at physiological temperatures, which has a propensity to form filaments.	4.52901e-14

Protein sequences

>NC_019679.1|WP_015122801.1|20766_21024_-|hypothetical-protein
MRTQILNQRTKCNKLARLEKKLAKLAVLKAKKQLLLRPHLAPVVVSNLMDFLSLNYTEVKGKILEVCSYKQRQKIEPILESTYVI
>NC_019679.1|WP_015122800.1|20537_20777_-|hypothetical-protein
MLSDSILIQNSEDERRWQFARELHEIRASLESLSERYPQQYKQVVEELLKKGDRITPTLKFLTEIEQLALEHYQDNLPN
>NC_019679.1|WP_044292677.1|20255_20516_-|hypothetical-protein
MRLQTQFIWAWAIAQAFSLSLKEEVMQIFGTNPKWFREDFDPKDLEVDIEPEVQHPQPEPLISSLEEELKRKKLSKLIMKTKLVNG
>NC_019679.1|WP_015122798.1|19680_20136_-|hypothetical-protein
MSSLISPEEFFDLVTGLSSQDKVIHACIDLLESLENDLHVKVRDGLKTYETSTISKMISHYRKPFYSYVSPLSVLNETVEIREYCPHGEFAHTFKRASRKHGAKAGDTLFYNLVQKQQHVAANLLALSEQQLLELVDRRIDNWILNEETAA
>NC_019679.1|WP_015122797.1|17733_19626_-|hypothetical-protein
MKEKIHVLTNIMSHQYTNEELTSLTKKEVYAIARKLADAQTTPQAAISKYSKDKLVDYIEEVQKMAIQSVEAQDKVETANAEAIPTPEEFFERVKRYNTKLEIHRACNELLEKLETEYAPSTVSKKLTYYKKPFYTFTHEKEELNEIITTTKGANKQSIAANLLKLSQEQNKVLNESREESELARKGVTAEGEIREVELPEVEIKKVIEKAIPLLKADQPELITCGILPLIGLRRNEQQMPYRTYLIDGELVDIQREFKVVGKFLIAVQGLSKKHGDRSWFLRPTLVPAEMIIEAQKRFLTFPKVRELTGDYEKFNDSALRKSTDRRFKEIWGDEFSTIEAYSEKGVKIDNNASTHKSRAFYIWALFPVLKYNKYNLKQAKAYLQRCLGHDDSKDTEKYFNRYDENQFTQGVDIEIPLNLKEVGKATEEKVFELAKEWEEEKLLEAQEKAEAEAEVKQEQLENLSSSFEGESKESSEETPLDKFIEEVIKGLSNKLQAEFSRLSVATKNPAKALTILINNLEKINTPPPKKVDIVEDSLKEIFGGIFLYNSAQPEDRDKVYPTYSLVNKIYSKLLDKEVGVTVYQRVFDELKTDIEEKVRLQNITEKQNNFHRKRMPQTIVKIVQYVDHV
>NC_019679.1|WP_015122796.1|17140_17731_-|hypothetical-protein
MPFEGCGCKICRAGLGEETNRLASDGSTIKEIKEYLKDNGLEVSKSLINKHLEAFDLKVGNSKLNQLETEFIEDKPLVEEITILNEINFENYAFEENSPQEIIGFVQRIALKIHLGVSAIALRDINYAQISGGEINTESINCYAKTQKALADITAIDVMVNQQKAIRTVESLGLKIENSNSLLPPRNLEQESKEEN
>NC_019679.1|WP_157229502.1|15610_17131_-|Terminase-like-family-protein
MNPSPKQIEKYYGRDDLLPLPEKWVDFAPLTLIRSGGQVIPFIPFAYQKKIIELAGKYNKIICIKSRQLGYTELWQNYALFEACTNPGTSAFLFLRNGVDASTSSRRTKLMMRGLVDYVRAANDSVYLLKIAGGGEVNFKNSGAEGARGANSSTFLLFDESAFIPSIAQIYGSSVPSGAMSDAIGKKPCLKVIQSTPSARSGWYWDQLSQNNGDRDIEEIIDSVVNGELYNENIPGFYWFEDDVGACKIVCHWSANEVYRKIPDFLEWRKKEDGTDEETIQREYQLKFNDQQVAVFDFGAVKSCAVGEWQATPEEGSIIYAGLDTATTGEDYVVLQVLAFKNGKYSLIHTYSKRKQTMEHHLFQICKVIEHYKIRKCGVEVTGGVGQVYYEKLVEEFRGKGIEFERLKTTQETKQKRISDFILALEKRSLIYPEKSNLVSELLSFRREGTKLSASHGKHDDEIMSLSFAYAVATSTEEVEWREQEYLDSLNPEEKLNYYQKLLESE
>NC_019679.1|WP_015122794.1|14823_15618_-|hypothetical-protein
MNNHFLSRLDKLRLQTNEVLKAQKSIETAFVKPKPPPIEVEDNVPPTPVRVTKLKPSNADKNYQRVCFEKYAEPDRIINENRYFTPIDRSQFKPGYFTILFSCDRNTTFESSIVSLIYQDGCFQILNKTIFEDLIDSKSFNLLLKKEIHIQVEKYSKTLEDNAQLILNPKVSTTDSSLASEMGTSSYYTTEQQPEKIHFTTYNPLKEDSDKDILKLRNLTSNKILKLPKDIAKDLFYNKDFSSLGTVTKALVPLNHYFETYCRH
>NC_019679.1|WP_015122793.1|14329_14821_-|hypothetical-protein
MYLQKLWLISVDHRISPDTTTILLFSEQNSGVILLEKCHVLESLSFSDLNKALSRLIAEFPISPSSRNRPTYSFVKTAYFWELDRAFEEDCTNSLLEAEQLEVAFKKYFKLQREGLFELTNERLIKSLNKFNGEYQSLNSQARAFLAALWWFKEKGFRGINIF
>NC_019679.1|WP_015122792.1|13925_14282_+|hypothetical-protein
MLLAQDNRRRKTRSSKDYSIEIEELKVKIKELSQSDKETVIAPIEGFPEACFKIARASAPSKLFKNKSEYDIFKYNWNHWELYFDGYVNQRNVEVDKSFYISVLKGRLKQLKELNKNR
>NC_019679.1|WP_015122802.1|22194_22683_-|GIY-YIG-nuclease-family-protein
MPFHHRSDNVPGYIYLIRAKNMHGLIPGRLLQRCKIGLSRDPQIRLDTFKSSQFPVDVEIITTIFVEDMAATEGELHEIFDFCNVKLEKSREWFDLSPWQYYRCLWAFKSRKSASFSISELPLTKLIKASLAIALVTTLGFAAYTAIPALAGKDSIEKVNKN
>NC_019679.1|WP_015122803.1|22776_24003_-|hypothetical-protein
MTTTNGHIMTEQTLNELPMIETVEQLAQETSKLGQEQKQLSPKKTTKPKSPKVKPNAITYVDVVLDAGSHSNKSMIDGFENAFSSVFKEIKGDLPSGMAGCFSYKGKNYIVGELADGFPGNLVYAYQDNKIKCLDIWLIGALTSDCDFLDTLMADKKSKNKYKNMPIRLSVNLKLLSLSSSKKGDISKILSNLKSFTYRGKEFELVINNLDDEFIYSEGYGAAMAAIKSLPDGTREFYVLDLGGGTTTATHYRNGRELPKAVNRFIATGGGMQIVAQQIYKAVSKTDMGGQELRLSGIFAALKACQRKEDGYFTPYCLGRKNIDISEEIPEGLQTWVDDNPTIKKVLTETRERLSSGFPVFATGGGFSCTIIADWITNYLTEDIPIANFQVLENSATINVSGMKLLND
>NC_019679.1|WP_015122804.1|24495_26826_-|hypothetical-protein
MKSIEVKGAARIVTIAGAILAVGSAIAFSQSEDGWGKSFSLNVGLLSAGVVAGGAAASYLVENQAKAETERVSQHYEDELKDNKRTIEDINTRLSSQNSTITTQQDKLISLDKLLAEKEIIIKQLKIAIQNIQTETKLKNLELDQKLQRENKDRQNLYLEMLDLFSSDLNYRIEESYNSLARTVASKLQNQKYISIQDKLQNFYNKLQTSLANSRKYLVELREVEFCTSDITDLYFQISDEISSRKVQLRNLLNTVERCTLLEFEKELEERRNPQNFVPRQKVLAALDNNDHHYSTQKQKFQAALNQEFNNLKELRESVNDLINQIDSKNLEIADLKTEINTHRSPLKWTLANSRELEIGNMIIDYFWKDGTNYYLDRSFMETDGYECKLYFQIDRNPRQIVESELNDKSEELQQFCRTLKPITFKYSGAKGLMVATVALKEKPKTDVDKSTVQRICKPHEVFAAAVGSYERWRVTGGSQAGKSPTAQYIAEAITKYSSKKVNVRLFNPQHGSKKDNWQYKAEGKNAEECLEGIKLLGEEIKNRQSKAKSTDLFDLFLVDELDSIVEEMGSGQVKSPLRYAIKQASHQDVGCIFIGQSSAANVVAGMTWSDWNSTAQLHLGDNAKGFIESRWKTENELREDYLKQFSMVRDYYERKNYEAGLTISDYGYFRFAFVAIPNQKPFFIEIPPFIFVPEDFQSVSTDDPLHEPLKKALSIAHAQADSETDCSPIAHQSSSTPKLQCHKCKSTDIKTKGDRYVCGNCCTTTKISTGKFKVK

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_019679_1	1.1|21592|35|NC_019679|PILER-CR,CRISPRCasFinder,CRT	21592-21626	35	NC_019679	Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence	21592-21626	0	1.0
NC_019679_1	1.2|21663|32|NC_019679|PILER-CR,CRISPRCasFinder,CRT	21663-21694	32	NC_019679	Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence	21663-21694	0	1.0
NC_019679_1	1.3|21731|36|NC_019679|PILER-CR,CRISPRCasFinder,CRT	21731-21766	36	NC_019679	Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence	21731-21766	0	1.0
NC_019679_1	1.4|21803|39|NC_019679|PILER-CR,CRISPRCasFinder,CRT	21803-21841	39	NC_019679	Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence	21803-21841	0	1.0
NC_019679_1	1.5|21878|37|NC_019679|PILER-CR,CRISPRCasFinder,CRT	21878-21914	37	NC_019679	Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence	21878-21914	0	1.0
NC_019679_1	1.6|21951|37|NC_019679|PILER-CR,CRISPRCasFinder,CRT	21951-21987	37	NC_019679	Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence	21951-21987	0	1.0
NC_019679_1	1.7|22024|35|NC_019679|PILER-CR,CRISPRCasFinder,CRT	22024-22058	35	NC_019679	Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence	22024-22058	0	1.0
NC_019679_1	1.2|21663|32|NC_019679|PILER-CR,CRISPRCasFinder,CRT	21663-21694	32	NZ_CP040855	Lactobacillus johnsonii strain G2A plasmid unnamed1	79032-79063	8	0.75
NC_019679_1	1.2|21663|32|NC_019679|PILER-CR,CRISPRCasFinder,CRT	21663-21694	32	NZ_CP015231	Epibacterium mobile F1926 plasmid unnamed1, complete sequence	306005-306036	8	0.75
NC_019679_1	1.2|21663|32|NC_019679|PILER-CR,CRISPRCasFinder,CRT	21663-21694	32	KF623293	Vibrio phage SHOU24, complete genome	25635-25666	9	0.719

1. spacer 1.1|21592|35|NC_019679|PILER-CR,CRISPRCasFinder,CRT matches to NC_019679 (Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttctctgtccatctggacattgagaaaatctccaa	CRISPR spacer
ttctctgtccatctggacattgagaaaatctccaa	Protospacer
***********************************

2. spacer 1.2|21663|32|NC_019679|PILER-CR,CRISPRCasFinder,CRT matches to NC_019679 (Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence) position: , mismatch: 0, identity: 1.0

cgtatctcctgctaaagctggaattgctgaag	CRISPR spacer
cgtatctcctgctaaagctggaattgctgaag	Protospacer
********************************

3. spacer 1.3|21731|36|NC_019679|PILER-CR,CRISPRCasFinder,CRT matches to NC_019679 (Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence) position: , mismatch: 0, identity: 1.0

ataaattttccctattgtcaagtattcactaggatg	CRISPR spacer
ataaattttccctattgtcaagtattcactaggatg	Protospacer
************************************

4. spacer 1.4|21803|39|NC_019679|PILER-CR,CRISPRCasFinder,CRT matches to NC_019679 (Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence) position: , mismatch: 0, identity: 1.0

aatccgaaggaactctaactgtatttgttccagaaaacg	CRISPR spacer
aatccgaaggaactctaactgtatttgttccagaaaacg	Protospacer
***************************************

5. spacer 1.5|21878|37|NC_019679|PILER-CR,CRISPRCasFinder,CRT matches to NC_019679 (Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence) position: , mismatch: 0, identity: 1.0

taataattattttgtctctttatctctacgtaagttc	CRISPR spacer
taataattattttgtctctttatctctacgtaagttc	Protospacer
*************************************

6. spacer 1.6|21951|37|NC_019679|PILER-CR,CRISPRCasFinder,CRT matches to NC_019679 (Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence) position: , mismatch: 0, identity: 1.0

tcaatagtttcggttattggttcaaaaatatattcga	CRISPR spacer
tcaatagtttcggttattggttcaaaaatatattcga	Protospacer
*************************************

7. spacer 1.7|22024|35|NC_019679|PILER-CR,CRISPRCasFinder,CRT matches to NC_019679 (Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence) position: , mismatch: 0, identity: 1.0

atactatagcctttctcagtttgaaacattaacat	CRISPR spacer
atactatagcctttctcagtttgaaacattaacat	Protospacer
***********************************

8. spacer 1.2|21663|32|NC_019679|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040855 (Lactobacillus johnsonii strain G2A plasmid unnamed1) position: , mismatch: 8, identity: 0.75

cgtatctcctgctaaagctggaattgctgaag	CRISPR spacer
aaactatcctgataaagctgaaattgctgaat	Protospacer
 .  * ***** ********.********** 

9. spacer 1.2|21663|32|NC_019679|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015231 (Epibacterium mobile F1926 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

cgtatctcctgctaaagctggaattgctgaag	CRISPR spacer
ttgaaatcttgctaaagctggcattgctgacg	Protospacer
.  *  **.************ ******** *

10. spacer 1.2|21663|32|NC_019679|PILER-CR,CRISPRCasFinder,CRT matches to KF623293 (Vibrio phage SHOU24, complete genome) position: , mismatch: 9, identity: 0.719

cgtatctcctgctaaagctggaattgctgaag	CRISPR spacer
tggctcttctgctaaagctgcaattgctactc	Protospacer
.*  ***.************ *******.   

2. NC_019678

CRISPR-Cas detection and classification

Crispr_ID: NC_019678_1

• CRISPR_ID: NC_019678_1
• CRISPR_location: 62891-63355
• CRISPR_type: Orphan
• Repeat_type: I-D,II-B
• Spacer_info: 6 spacers

Consensus repeat of NC_019678_1

Consensus_repeat	Method
GTTGAAATCAACTTAAATCCCTATTAGGG----------ATTGAAAC	PILER-CR
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	CRISPRCasFinder
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	CRT

spacers of NC_019678_1

>1.1|62928|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CTTAAGTAGTATTAATTCTGAGAAAAATTCAATA
>1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CCAATGACAAAAATATATGACTAAATATAAGAAA
>1.3|63070|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
ATTTAATATATATGGGAAAATCCCGCTTCTAGAG
>1.4|63141|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AGAAGGCTTTAATCGAATGGAAATTCCGGATATT
>1.5|63212|36|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TATAGAAAAAACCAAGATAATCATCAGCCAAGTCCT
>1.6|63285|34|NC_019678|CRT
TTTCAATAATTTGCATAAGCCTAACTAATTGATT

CRISPR arrays and Neighbor proteins around NC_019678_1

CRISPR arrays

The CRISPR arrays of NC_019678_1

>merge|NC_019678|1|62891-63355|PILER-CR,CRISPRCasFinder,CRT
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAACCTTAAGTAGTATTAATTCTGAGAAAAATTCAATAGTTGAAATCAACTTAAATCCCTATTAGGGATTGAAACCCAATGACAAAAATATATGACTAAATATAAGAAAGTTGAAATCAACTTAAATCCCTATTAGGGATTGAAACATTTAATATATATGGGAAAATCCCGCTTCTAGAGGTTGAAATCAACTTAAATCCCTATTAGGGATTGAAACAGAAGGCTTTAATCGAATGGAAATTCCGGATATTGTTGAAATCAACTTAAATCCCTATTAGGGATTGAAACTATAGAAAAAACCAAGATAATCATCAGCCAAGTCCTGTTGAAATCAACTTAAATCCCTATTAGGGATTGAAACTTTCAATAATTTGCATAAGCCTAACTAATTGATTGTTGAAATCAACTCAAATCTTGCACTATCCTCGACAC

>NC_019678|1|1|62891-63284|PILER-CR
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	CTTAAGTAGTATTAATTCTGAGAAAAATTCAATA
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	CCAATGACAAAAATATATGACTAAATATAAGAAA
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	ATTTAATATATATGGGAAAATCCCGCTTCTAGAG
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	AGAAGGCTTTAATCGAATGGAAATTCCGGATATT
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	TATAGAAAAAACCAAGATAATCATCAGCCAAGTCCT
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC

>NC_019678|1|1|62891-63284|CRISPRCasFinder
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	CTTAAGTAGTATTAATTCTGAGAAAAATTCAATA
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	CCAATGACAAAAATATATGACTAAATATAAGAAA
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	ATTTAATATATATGGGAAAATCCCGCTTCTAGAG
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	AGAAGGCTTTAATCGAATGGAAATTCCGGATATT
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	TATAGAAAAAACCAAGATAATCATCAGCCAAGTCCT
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC

>NC_019678|1|1|62891-63355|CRT
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	CTTAAGTAGTATTAATTCTGAGAAAAATTCAATA
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	CCAATGACAAAAATATATGACTAAATATAAGAAA
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	ATTTAATATATATGGGAAAATCCCGCTTCTAGAG
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	AGAAGGCTTTAATCGAATGGAAATTCCGGATATT
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	TATAGAAAAAACCAAGATAATCATCAGCCAAGTCCT
GTTGAAATCAACTTAAATCCCTATTAGGGATTGAAAC	TTTCAATAATTTGCATAAGCCTAACTAATTGATT
GTTGAAATCAACTCAAATCTTGCACTATCCTCGACAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015116245.1|64001_64919_-|TIGR02587-family-membrane-protein	unknown	unknown	gnl|CDD|370584
NC_019678.1|WP_015116235.1|52473_54486_-|M48-family-metalloprotease	unknown	unknown	gnl|CDD|320697
NC_019678.1|WP_015116249.1|69183_70605_-|isochorismate-synthase	unknown	unknown	gnl|CDD|224091
NC_019678.1|WP_015116248.1|67355_68666_+|glutamate-5-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|234685
NC_019678.1|WP_015116247.1|66143_66626_-|peptidoglycan-binding-protein	unknown	unknown	gnl|CDD|225943
NC_019678.1|WP_044290691.1|61014_61623_+|metal-binding-protein	unknown	unknown	gnl|CDD|370771
NC_019678.1|WP_015116233.1|50626_51499_-|rhodanese-related-sulfurtransferase	unknown	unknown	gnl|CDD|223982
NC_019678.1|WP_015116237.1|55411_56035_-|DUF938-domain-containing-protein	unknown	unknown	gnl|CDD|253548
NC_019678.1|WP_015116234.1|51850_52216_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_052330778.1|57394_57907_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015116239.1|58531_59659_-|hypothetical-protein	unknown	unknown	gnl|CDD|379160
NC_019678.1|WP_015116250.1|70909_71806_+|2-carboxy-1,4-naphthoquinone-phytyltransferase	unknown	unknown	gnl|CDD|236015
NC_019678.1|WP_015116246.1|65580_65904_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_044290694.1|74569_74980_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015116252.1|72949_74413_+|2-succinylbenzoate--CoA-ligase	unknown	unknown	gnl|CDD|236019
NC_019678.1|WP_015116236.1|54860_55241_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015116243.1|61785_62580_+|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl|CDD|236569
NC_019678.1|WP_015116251.1|71987_72977_+|o-succinylbenzoate-synthase	unknown	unknown	gnl|CDD|235061
NC_019678.1|WP_015116240.1|59725_60379_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015116244.1|63594_64005_-|TIGR02588-family-protein	unknown	unknown	gnl|CDD|131637

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015116245.1|64001_64919_-|TIGR02587-family-membrane-protein	gnl|CDD|370584	pfam09622, DUF2391, Putative integral membrane protein (DUF2391). This entry is found in Nostoc sp. PCC 7120, Agrobacterium tumefaciens, Rhizobium meliloti, and Gloeobacter violaceus in a conserved two-gene neighborhood. Proteins containing this entry appear to span the membrane seven times.	9.71888e-139
NC_019678.1|WP_015116235.1|52473_54486_-|M48-family-metalloprotease	gnl|CDD|320697	cd07338, M48B_HtpX_like, Peptidase M48 subfamily B HtpX-like membrane-bound metallopeptidase. This HtpX family of peptidase M48 subfamily B includes uncharacterized HtpX homologs and consists of proteins smaller than Ste24p, with homology restricted to the C-terminal half of Ste24p. HtpX expression is controlled by the Cpx stress response system, which senses abnormal membrane proteins. HtpX participates in the proteolytic quality control of these misfolded proteins by undergoing self-degradation and collaborating with FtsH, a membrane-bound and ATP-dependent protease, to eliminate them. HtpX, a zinc metalloprotease with an active site motif HEXXH, has an FtsH-like topology, and is capable of introducing endoproteolytic cleavages into SecY (also an FtsH substrate). However, HtpX does not have an ATPase activity and will only act against cytoplasmic regions of a target membrane protein. Thus, HtpX and FtsH have overlapping and/or complementary functions, which are especially important at high temperature; in E. coli and Xylella fastidiosa, HtpX is heat-inducible, while in Streptococcus gordonii it is not.	8.18073e-68
NC_019678.1|WP_015116250.1|70909_71806_+|2-carboxy-1,4-naphthoquinone-phytyltransferase	gnl|CDD|236015	PRK07419, PRK07419, 2-carboxy-1,4-naphthoquinone phytyltransferase.	4.45177e-166
NC_019678.1|WP_015116248.1|67355_68666_+|glutamate-5-semialdehyde-dehydrogenase	gnl|CDD|234685	PRK00197, proA, gamma-glutamyl phosphate reductase; Provisional.	0
NC_019678.1|WP_015116247.1|66143_66626_-|peptidoglycan-binding-protein	gnl|CDD|225943	COG3409, COG3409, Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane].	3.69285e-25
NC_019678.1|WP_044290691.1|61014_61623_+|metal-binding-protein	gnl|CDD|370771	pfam09988, DUF2227, Uncharacterized metal-binding protein (DUF2227). Members of this family of hypothetical bacterial proteins possess metal binding properties; however, their exact function has not, as yet, been determined.	6.62365e-78
NC_019678.1|WP_015116233.1|50626_51499_-|rhodanese-related-sulfurtransferase	gnl|CDD|223982	COG1054, COG1054, Predicted sulfurtransferase [General function prediction only].	5.36483e-156
NC_019678.1|WP_015116237.1|55411_56035_-|DUF938-domain-containing-protein	gnl|CDD|253548	pfam06080, DUF938, Protein of unknown function (DUF938). This family consists of several hypothetical proteins from both prokaryotes and eukaryotes. The function of this family is unknown.	3.8693e-91
NC_019678.1|WP_015116239.1|58531_59659_-|hypothetical-protein	gnl|CDD|379160	pfam13395, HNH_4, HNH endonuclease. This HNH nuclease domain is found in CRISPR-related proteins.	9.33977e-08
NC_019678.1|WP_015116249.1|69183_70605_-|isochorismate-synthase	gnl|CDD|224091	COG1169, MenF, Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.40317e-126
NC_019678.1|WP_015116243.1|61785_62580_+|nucleoside-triphosphate-pyrophosphohydrolase	gnl|CDD|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	6.742e-136
NC_019678.1|WP_015116251.1|71987_72977_+|o-succinylbenzoate-synthase	gnl|CDD|235061	PRK02714, PRK02714, o-succinylbenzoate synthase.	2.8777e-175
NC_019678.1|WP_015116252.1|72949_74413_+|2-succinylbenzoate--CoA-ligase	gnl|CDD|236019	PRK07445, PRK07445, O-succinylbenzoic acid--CoA ligase; Reviewed.	0
NC_019678.1|WP_015116244.1|63594_64005_-|TIGR02588-family-protein	gnl|CDD|131637	TIGR02588, TIGR02588, TIGR02588 family protein. The function of this protein is unknown. It is always found as part of a two-gene operon with TIGR02587, a protein that appears to span the membrane seven times. It is found in Nostoc sp. PCC 7120, Agrobacterium tumefaciens, Sinorhizobium meliloti, and Gloeobacter violaceus, so far, all of which are bacterial. [Hypothetical proteins, Conserved].	1.5023e-39

Protein sequences

>NC_019678.1|WP_015116243.1|61785_62580_+|nucleoside-triphosphate-pyrophosphohydrolase
MDTLTALQELIDVVAKLRSPNGGCPWDLAQTPETLTPYVIEEAYEVVDAIKSGDKNHVAEELGDLLLQVVLQAQIYSESGDFTLKEVAEGISQKLIRRHPHVFGDVSVQNVDEVKQNWEDIKAAEKGETVAETQKLSNKLFGYTRKLPPLMATMKMSKKAADVGFEWDDIDGVWEKYEEELGEFKQALAEETPERQQEELGDLLFTLLQLARWNNLDPSEALQGTNKRFIQRFQKMENFAERPLSEYSLVELEELWQQAKKELK
>NC_019678.1|WP_044290691.1|61014_61623_+|metal-binding-protein
MPSGQTHDRITIWALPFIAGTTFWQTHSSSITLLIAGGFMFGGLMFGPDLDIYSIQYQRWGYFRFIWLPYQKSLRHRSFLSHGPLIGTTVRVLYLCVLISIVTIIVLLIAEKLLNMTLSWQEVAKHLLDIINLHKTEFLALFVGLELGAMSHSISDWSNSAYKRFKRKGITSLLPKKKPKKRKYVSKSTTNRRSKSKARRRR
>NC_019678.1|WP_015116240.1|59725_60379_-|hypothetical-protein
MTQTAITKRITTIAEAEKQFNLVRTADVNFFTEWRENLADIIDAEKAVLDRIKARYRYHRVNGNLAESLVNLLVLSPLLELAGFYDPPYLMQGEVAVEVSTSVAESEVSDEILRGRIDFLVVSKGLWIAVLESKGTEINLDMAIPQTLTYMMANPDATKPVFAMATNGGDFFFLKLNRQGTPQYDISRIFSLLPLQNELYDVLKILKQLGKGIEDID
>NC_019678.1|WP_015116239.1|58531_59659_-|hypothetical-protein
MYNLPNDDSLDISALSRLFESTTNSYKYLYFLSLLDIIRRNNFDIVSPISFKDIIVEMLANAWYPHNYFKLSFGTQDHISNKLDSLKLEITEPILKFRDTDKKLLRTAISNQNINDIVAFISNYVPYRLIRPFFAEDTRGFKDYDVNSAIINLSKNKFDNKKPLYCFNAQKQKDCNAIILYPDWIDYFKKNYVLVRGWASWEWLKYMQQRNPNIPNVVNKLFMPQQRDSLSKQTKYWKTVLTYREINCIYSEVQLNKNEISLDHYLPWSFVAHDQLWNLIPTTPSVNSSKSNNLPSQIYFADFINLQHLGLTVSYNHIPQNKWLKDIEPFICDLKINQADNLLNLEILTNAYEITLQPLITLASNQGFSANWVYA
>NC_019678.1|WP_052330778.1|57394_57907_-|hypothetical-protein
MKSAIYKEYLTRINQIENQNIPLEQLRFSVDLSLDIVSNENWIPTLRNPEELYLAYSGKEDKLTAIARNHAINDLKYLNIIPNLNQNNFNAYVGIKLLEKPIIQKIDKFVQVPQRFGVVRDFLASLLSANLPNLNPERAWQSLMRWLLYFLPSRYALSVPNYSEVFYRIK
>NC_019678.1|WP_015116237.1|55411_56035_-|DUF938-domain-containing-protein
MDKRKRALATERNREPILQVLLEVLPPTGTVLEIASGTGEHAAYFAPQLKPRKWIPSDPDASLRESISAWAQYCPSENLSQPLDIDASQPVWKAEKEILSEISDICAIVNINMIHISKWPACLGLIAAAGRILPSGGILYLYGPYKQGGEHTAPSNAAFSEYLQEQNPEWGVRNLEDVVEVAKTNHLILQKTYPMPANNLSVVFKHS
>NC_019678.1|WP_015116236.1|54860_55241_-|hypothetical-protein
MSDVNGTWLGTYWQNGNPTRFEVVLVQSGNSLSGRVLDDSYLGEAKLSGEVVGRRISFIKSYFTSSPDAIEYVGTISEDEDYIQGQWRIGSWDYGPWEARRSGESLSLEVGNKSEKKVPVTVNSYQ
>NC_019678.1|WP_015116235.1|52473_54486_-|M48-family-metalloprotease
MSLQAGIDAAKEGRYQEAIPLLEQYCRNCAEQSSAEYCTAQMWLIRGYKATGEIEKALILCQRLMQSEHTKVSDWAGNMYQKLNNSTTETEATEEPNTVKKAVGAAGVKLAMAGVGGNLALASTVTMSLMFGMVLVLALGIILIADSENPVAGLGIAIAITVLFNIAAFFLSPFLMDLTQNWLYKTRWVELAEIENLSPETIRVIRRVCQQKKIKTPRLGIIEDQNPTAFTYGSLPNSARLVVSRGLFTYLDDDEVATVYAHELGHIVHWDFAVMTVASTLVQICYLIYTTARTLGRSMGDSKIADAAKSASLAAYIFYFIGTYLLLYLSRTREYFADHFAAEVTGNPNGLSRSLVKIAYGIVEEGSRAKEPSRLIEGTRALGIYDAKAAATTGNAYRIASKPEKIGRVFLWDMFNPWGWWMELSSTHPLTGKRVRALSTYAEQLGLETEFDMGKVVGEGKNLNKKKLYGNFFTDILFFAAETIGLFVGIAVGIILESSGLNNPGLFVACPLIGVAIGIIIKAFVTYPNYEKAVETDVLTLMSDPYASPLRGRPAKLQGKLIGRGDAGYKFGSDLKIQDPSGMLYLRYASRFGSIGNFLFGMKRVESLINMNVSSVGWFRRGVAPWMDLIELKSENGTVVNSYHRFGSFVTAGFLIVLGIGLMVLFGGLS
>NC_019678.1|WP_015116234.1|51850_52216_-|hypothetical-protein
MTFNSNQDQENNSPWNPFVPTARDIERTDELAGKNPAIAGVLSFFLLPAAMIYLNRGINNLKILGYVFVAGVMIGMVTSNRNSRDTNPAANLIGVLGNIAVIAENTRTITLARKRQSEINE
>NC_019678.1|WP_015116233.1|50626_51499_-|rhodanese-related-sulfurtransferase
MSVIVAALYQFVKLPDYAQIRQPLLSTCEANEIKGTLLLAQEGINGTIAGSRQGIDIVIDFLRSDSRFTDLEYKESIAESPPFQRMKVRLKKEIVTLGLSEVNPSEQVGTYVNPKDWNEIISNPEVTVIDTRNDYEVSIGTFKRAENPQTESFREFPEYASKNLNQNKNKKVAMFCTGGIRCEKATSYLLSQGFEEVYHLKGGILKYLEEVPPEESLWEGECFVFDQRVAVRHGLEPGSYDMCPSCGHPISDDDKASSKYEEGISCPYCFDHLTEDKKAKMQEKKRQREE
>NC_019678.1|WP_015116244.1|63594_64005_-|TIGR02588-family-protein
MSQPKQDKQEQKRTIAEWATFCIASSILLGVIGLVSFTWIKQPAQKPPALVVTNNKPLRKVNEQYYVHFEVINKGEETAASVQVIAELRLNGKVEETGEQQIEFLSRGEKETGAFVFTKNPNQGELILRIASYKSP
>NC_019678.1|WP_015116245.1|64001_64919_-|TIGR02587-family-membrane-protein
MKFKSRRRICAKYKNNTKRKRQKNPWKSEINDIVRGGCGGFLFGIPLLYTMEVWWIGSSATPEMMLMALLLTFIVVYLLMRTEGFRKPKRFSRRYQAITETVEAMGIGLVCSAFMLLLLQELSAGVSLKEALGKIIFESVPFSLGVALANQLLGENGNNPPDNRTSSQNDLVDNNPTFTDLSATLIGATVIGFNIAPTDEIATLAAAVSEPWLLAIIAISLLISYAIVFQAGFSAQEKRRQHQGIFQKPFSETMICYLVSLISAAIMLWFFQKLAWSDPWTIWLEHSIILGLPTTIGGAAGRLAI
>NC_019678.1|WP_015116246.1|65580_65904_+|hypothetical-protein
MPKLTKLFLVISCFIVILLNGCTPNKENNWTHKFSRIFRDDYRVTLYSGGKAVREWQLKHSNVNYEKNDDGWFFSCQKHLVVIRGEEIVIEPLAYSQQQVENPIICN
>NC_019678.1|WP_015116247.1|66143_66626_-|peptidoglycan-binding-protein
MTSISNFHSVKSQLNKPVLTQGSSGQAVLELQKLLKHWRCYCGEIDGIFGPQTTAAVNCFEYWMFLAEDGIVDENTWLSLYKGAPVDMPVLQKRSQGELVEKIQERLLWSGFFQSAITGYFGIVTENAIKDLQQRTGLAPDGIVGDRTWLELSKIREYSY
>NC_019678.1|WP_015116248.1|67355_68666_+|glutamate-5-semialdehyde-dehydrogenase
MTVLIHNSDLILTAKQTRLAAMKLAVLSTAAKNEAIEAIAVALLSAQDEIIQANISDCEAATSEGIAKPLYKRLQLDEHKLRDNIAGVRDIGKLSDPVGNIQIHRKLDTGLILKRVSCPLGVLGVIFEARPEAAIQIASLAIKSGNGVILKGGKEAIRSCEAIVKAIKQGLSKTTVDPDAVQLLTTREETLELLKLDKYVDLIIPRGSNSFVQFVQQNTSIPVLGHADGICHLYIDKSADMQKAVDITVDAKTHYPAACNAIETLLVDRDIASTFLPKAAQALQKLNVELRGDEATQAILPNIVPATEADWETEYSDLILSIKIVDSLPEAISHINEYGSKHTDAIVTENIEAAENFLSLVDAAGVYHNCSTRFADGFRYGFGAEVGISTQQIPPRGPVGLEGLVTYKYKMTGNGHVASSYTGEDAKPFLHKDLLQ
>NC_019678.1|WP_015116249.1|69183_70605_-|isochorismate-synthase
MTVSPCSAEFFVYNKELYQFLVKKRAYCIKNNCTQIASIGLEIDSVDPLVVFQKLSASNKLNFYWENPSKEEAIAAIDAVTKFHIEGKERFIQAEKFIKYNLGKIINFCNVNHSFSQPLFFCSFSFFDTNLQENYPFFPATVFLPKWQVTRKEKCCILRANIKIDADLNIEKTLKILWQKITSINLLKYDAVDLDNSQPQFIKNSITKSSKFQRSVLSALEDIRKGTYSKIVLADALNIQSSTPLNLFKSLNNLRQLHPNCCVFSTSNGKGQNFIGASPETLIAIRNQKLNTDALAGSAARGKTPAEDAKKANLLLNSQKERHEHSLVIDFITQKLLSLGLLPQVSTPRLRQLSNIQHLWTPIIAKVPRNVHPLQIVSQLHPTPAVAGVAPEVACQEIRRYESFERGLYAAPLGWIDAEGNCEFVVGIRSALIDTSTKSSLLYAGAGIVPGSDPQKEFAEIQLKLQALLKALT
>NC_019678.1|WP_015116250.1|70909_71806_+|2-carboxy-1,4-naphthoquinone-phytyltransferase
MTTKLILYPNIRLWMAALKPPMYCVAIMPIWVGTAIAFAETRVLHTAVFCTFLAAAILILAWENLSNDVFDSDTGIDINKHHSLVNLTGSRQLILWLGNCFLASGLFGILTISWWQKDLTLIGIILICCGLGYLYQGPPFRLGYKGLGEILCFFAFGPLGVAAGYYSQTQSYSLTSLAASVIVGITTTLILFCSHFHQVEDDLAAGKLSPIVRLGTLKGSQVLKWFTGSIYALIFIFILCGIFPLWTLLSWFSLPFAAKLYNHVSQNHDKPLEISNLKFIAIAVQFWCCLLLGLGFVL
>NC_019678.1|WP_015116251.1|71987_72977_+|o-succinylbenzoate-synthase
MFYKFEFRTYSRKFVTPLNTSHGVWESRNGLIIRLRDETGKVGWGEIAPISWFGSETVEEAISFCRKLPQTITENIIFSIPDELPACQFGFESAREMINKNYFSAESSPITSSILLPAGRAALHQWRNIWEYGSHSFKWKIGVYPFAEEIFIFDLLAGELPAFTKLRLDANAGLSYGEAEIWLRKCDEINKNDDIDLKIEFIEQPLAVDRFSEMLELSRIYNTKIALDESVATLKQLESCYQRGWRGIFVIKAGIIGSPSRLRRFCLNHEVDTVFSSVFETNIGREAALSLAAELSQQKRAVGFGVNHFFAEDEQTCLKNLWKETSSIL
>NC_019678.1|WP_015116252.1|72949_74413_+|2-succinylbenzoate--CoA-ligase
MEGNFKYFVDNDCLICEDSHLLVELVEKLDFDIFQFKQQHSYLPKIILNERQPVRFLAGFIAACKANCPVFLCNPDWGKQEWLQVFDLVKPDIIWGIKPKAVEASYFLENSHNTDIYNAPCPIPNAQSPYIMIPTGGSSGRIKFAVHTWDTLTASVLGFKEYFQVDQINSFCVLPLYHVSGLMQFMRCFITGGKLIVLPFKSLESKPVSYSKNNFNQLISSSEYFISLVPTQLERLLQKSDLAEWLSKFQTVLLGGAPAWNELLQKARFHCIRLAPTYGMTETASQIATMKSDDFIQGKVGCGKILPHAKITICGKKGEELKVNQIGNINIQAKSLALGYYPLSSKTQTCLQIDDLAFLNEQGYLNIVGRNSDKIITGGENVYPTEVEAVIRATGMVADVCVIGLADKYWGEVVTAIYVVNSGINHPAVKMPALQQDKNERILIQTLLKEKLSNYKIPKVWIPVDSLPRNSQGKINRQKLYEIAVSK
>NC_019678.1|WP_044290694.1|74569_74980_-|hypothetical-protein
MNTKKHFQLLAYSFITWLIFYIIGLPDYYQQWYFWAKIAVCVFVTLIYFPITQYTLKKYWTDGKHLVNSCWLALYLTLPLFVYDYLLLAVYKGLGIGFVIPYWYLTFFYFSFWIQFPLVGWWMQRTKTQSVEASAF

Crispr_ID: NC_019678_2

• CRISPR_ID: NC_019678_2
• CRISPR_location: 233441-233533
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: DEDDh

Consensus repeat of NC_019678_2

Consensus_repeat	Method
GGGTGTGGATCATCAACTAACAA	CRISPRCasFinder

spacers of NC_019678_2

>2.1|233464|47|NC_019678|CRISPRCasFinder
CTAACAACTATCAACCATCAACCATCAACTAACAACTTTCACCGGTC

CRISPR arrays and Neighbor proteins around NC_019678_2

CRISPR arrays

The CRISPR arrays of NC_019678_2

>merge|NC_019678|2|233441-233533|CRISPRCasFinder
GGGTGTGGATCATCAACTAACAACTAACAACTATCAACCATCAACCATCAACTAACAACTTTCACCGGTCGGGTGTGGATCATCAACTATCAA

>NC_019678|2|2|233441-233533|CRISPRCasFinder
GGGTGTGGATCATCAACTAACAA	CTAACAACTATCAACCATCAACCATCAACTAACAACTTTCACCGGTC
GGGTGTGGATCATCAACTATCAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015116376.1|238811_238901_-|cytochrome-b6-f-complex-subunit-PetN	unknown	unknown	gnl|CDD|367633
NC_019678.1|WP_015116377.1|239016_239487_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015116369.1|230201_230726_-|DUF2808-domain-containing-protein	unknown	unknown	gnl|CDD|371328
NC_019678.1|WP_015116364.1|227122_227638_-|RNA-binding-protein	unknown	unknown	gnl|CDD|224760
NC_019678.1|WP_015116378.1|239512_240058_+|exonuclease-domain-containing-protein	DEDDh	cd06127_DEDDh_CAS-I	gnl|CDD|99836
NC_019678.1|WP_015116372.1|233552_234953_+|NAD(P)(+)-transhydrogenase-(Re/Si-specific)-subunit-beta	unknown	unknown	gnl|CDD|376743
NC_019678.1|WP_015116373.1|235518_238356_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|315987
NC_019678.1|WP_015116370.1|231706_232867_+|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha	unknown	unknown	gnl|CDD|240629
NC_019678.1|WP_015116379.1|240274_241270_-|pyrroloquinoline-quinone-(coenzyme-PQQ)-biosynthesis-protein-C	unknown	unknown	gnl|CDD|379634
NC_019678.1|WP_015116367.1|229423_229846_-|ribonuclease-P-protein-component	unknown	unknown	gnl|CDD|235100
NC_019678.1|WP_015116383.1|243472_243751_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015116368.1|229881_230016_-|50S-ribosomal-protein-L34	unknown	unknown	gnl|CDD|179004
NC_019678.1|WP_015116380.1|241320_242361_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015116366.1|229044_229437_-|PH-domain-containing-protein	unknown	unknown	gnl|CDD|367615
NC_019678.1|WP_015116382.1|242927_243224_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015116371.1|233093_233381_+|NAD(P)-transhydrogenase-subunit-alpha	unknown	unknown	gnl|CDD|378941
NC_019678.1|WP_015116381.1|242496_242799_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015116362.1|225797_226352_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015116365.1|227637_228792_-|membrane-protein-insertase-YidC	unknown	unknown	gnl|CDD|235058
NC_019678.1|WP_015116363.1|226522_227026_-|hypothetical-protein	unknown	unknown	gnl|CDD|224317

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019678.1|WP_015116378.1|239512_240058_+|exonuclease-domain-containing-protein	DEDDh	cd06127_DEDDh_CAS-I	8.5e-13	43.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015116376.1|238811_238901_-|cytochrome-b6-f-complex-subunit-PetN	gnl|CDD|367633	pfam03742, PetN, PetN. PetN is a small hydrophobic protein, crucial for cytochrome b6-f complex assembly and/or stability.	9.59528e-06
NC_019678.1|WP_015116369.1|230201_230726_-|DUF2808-domain-containing-protein	gnl|CDD|371328	pfam10989, DUF2808, Protein of unknown function (DUF2808). This family of proteins with unknown function appears to be restricted to Cyanobacteria.	2.91607e-45
NC_019678.1|WP_015116364.1|227122_227638_-|RNA-binding-protein	gnl|CDD|224760	COG1847, Jag, Predicted RNA-binding protein [General function prediction only].	6.99673e-45
NC_019678.1|WP_015116378.1|239512_240058_+|exonuclease-domain-containing-protein	gnl|CDD|99836	cd06133, ERI-1_3'hExo_like, DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins. This subfamily is composed of Caenorhabditis elegans ERI-1, human 3' exonuclease (3'hExo), Drosophila exonuclease snipper (snp), and similar proteins from eukaryotes and bacteria. These are DEDDh-type DnaQ-like 3'-5' exonucleases containing three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. ERI-1 has been implicated in the degradation of small interfering RNAs (RNAi). 3'hExo participates in the degradation of histone mRNAs. Snp is a non-essential exonuclease that efficiently degrades structured RNA and DNA substrates as long as there is a minimum of 2 nucleotides in the 3' overhang to initiate degradation. Snp is not a functional homolog of either ERI-1 or 3'hExo.	1.62169e-75
NC_019678.1|WP_015116372.1|233552_234953_+|NAD(P)(+)-transhydrogenase-(Re/Si-specific)-subunit-beta	gnl|CDD|376743	pfam02233, PNTB, NAD(P) transhydrogenase beta subunit. This family corresponds to the beta subunit of NADP transhydrogenase in prokaryotes, and either the protein N- or C terminal in eukaryotes. The domain is often found in conjunction with pfam01262. Pyridine nucleotide transhydrogenase catalyzes the reduction of NAD+ to NADPH. A complete loss of activity occurs upon mutation of Gly314 in E. coli.	0
NC_019678.1|WP_015116373.1|235518_238356_+|tetratricopeptide-repeat-protein	gnl|CDD|315987	pfam13424, TPR_12, Tetratricopeptide repeat.	7.52872e-13
NC_019678.1|WP_015116370.1|231706_232867_+|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha	gnl|CDD|240629	cd05304, Rubrum_tdh, Rubrum transdehydrogenase NAD-binding and catalytic domains. Transhydrogenases found in bacterial and inner mitochondrial membranes link NAD(P)(H)-dependent redox reactions to proton translocation. The energy of the proton electrochemical gradient (delta-p), generated by the respiratory electron transport chain, is consumed by transhydrogenase in NAD(P)+ reduction. Transhydrogenase is likely involved in the regulation of the citric acid cycle. Rubrum transhydrogenase has 3 components, dI, dII, and dIII. dII spans the membrane while dI and dIII protrude on the cytoplasmic/matrix side. DI contains 2 domains in Rossmann-like folds, linked by a long alpha helix, and contains a NAD binding site. Two dI polypeptides (represented in this sub-family) spontaneously form a heterotrimer with dIII in the absence of dII. In the heterotrimer, both dI chains may bind NAD, but only one is well-ordered. dIII also binds a well-ordered NADP, but in a different orientation than a classical Rossmann domain.	0
NC_019678.1|WP_015116379.1|240274_241270_-|pyrroloquinoline-quinone-(coenzyme-PQQ)-biosynthesis-protein-C	gnl|CDD|379634	pfam14518, Haem_oxygenas_2, Iron-containing redox enzyme. The CADD, Chlamydia protein associating with death domains, crystal structure reveals a dimer of seven-helical bundles. Each bundle contains a di-iron centre adjacent to an internal cavity that forms an active site similar to that of methane mono-oxygenase hydrolase.	2.29408e-06
NC_019678.1|WP_015116367.1|229423_229846_-|ribonuclease-P-protein-component	gnl|CDD|235100	PRK03031, rnpA, ribonuclease P protein component.	4.57556e-60
NC_019678.1|WP_015116368.1|229881_230016_-|50S-ribosomal-protein-L34	gnl|CDD|179004	PRK00399, rpmH, 50S ribosomal protein L34; Reviewed.	1.03661e-07
NC_019678.1|WP_015116366.1|229044_229437_-|PH-domain-containing-protein	gnl|CDD|367615	pfam03703, bPH_2, Bacterial PH domain. Domain found in uncharacterized family of membrane proteins. 1-3 copies found in each protein, with each copy flanked by transmembrane helices. Members of this family have a PH domain like structure.	7.96989e-12
NC_019678.1|WP_015116371.1|233093_233381_+|NAD(P)-transhydrogenase-subunit-alpha	gnl|CDD|378941	pfam12769, PNTB_4TM, 4TM region of pyridine nucleotide transhydrogenase, mitoch. PNTB_4TM is the region upstream of family PNTB, pfam02233, that carries four of this transporters transmembrane regions. PNTB is the beta-subunit of pyridine nucleotide transhydrogenase. This family forms part of the Proton-translocating Transhydrogenase (PTH) Family.	3.70076e-38
NC_019678.1|WP_015116365.1|227637_228792_-|membrane-protein-insertase-YidC	gnl|CDD|235058	PRK02654, PRK02654, putative inner membrane protein translocase component YidC; Provisional.	0
NC_019678.1|WP_015116363.1|226522_227026_-|hypothetical-protein	gnl|CDD|224317	COG1399, COG1399, Predicted metal-binding, possibly nucleic acid-binding protein [General function prediction only].	5.39616e-23

Protein sequences

>NC_019678.1|WP_015116371.1|233093_233381_+|NAD(P)-transhydrogenase-subunit-alpha
MTEALIAALFVFVLASFTGFEVINKVPPTLHTPLMSGSNAISGIAVLGAIVAAGAKESSLSVTLGLIAVTLATINVVGGFLVTDRMLQMFKKKAS
>NC_019678.1|WP_015116370.1|231706_232867_+|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha
MRIAVAKEIEASERRVALIPDVVSKLVKQGFEIWIESGAGEKALFNDSDYETAGATVISDTAKLWGEADILLKVSPPQQREEGGTEVDLLKEGSVFIGFLNPLANPSVAEQLAQRKVTAFSMEMIPRTTRAQSMDALSSQASIAGYKSVLIAAEALPKYFPMLTTAAGTIAPAKVFVMGAGVAGLQAIATARRLGAMVEAFDIRPAVKEEVQSLGAKFVEVKLDEETATAGGYAKEISEESKRKTQEAVNDRVKNADVVITTAQVPGRKAPRLVTEEMIAEMKPGAVIVDLAADQGGNAAYTEPGGNVVKNGVTIIGPVNLPSSVPVHASQLYSKNLVSLMKLLTKDNALNLNFEDDIVNAACVTHSGEIRNQRVKDALQALTVNS
>NC_019678.1|WP_015116369.1|230201_230726_-|DUF2808-domain-containing-protein
MRRLLSAVAVSGFLLAGVPAITTAQGLPGLTLFSGVKSENQLSYRLDFGGQTRDWDRYRLRIPGKKLKMAVEKFVIAYPDYYDGEFDTDEIEIKVGRGKGKKVKVSEVKWDKEGKVIEIIPEKPIPAGKSTELILSNVENPDFPGTFYFNCLIQSPGDKTALTRYVGTWIIGIN
>NC_019678.1|WP_015116368.1|229881_230016_-|50S-ribosomal-protein-L34
MKRTLGGTCRKRKRTSGFRARMRTPDGRNVIRARRKKGRHRLSV
>NC_019678.1|WP_015116367.1|229423_229846_-|ribonuclease-P-protein-component
MALPSANRLKSRHDFRAVFREGFRCHGSYMTLRALKPRHGKLPSSDTPGENDQENKPASVTPPRIGISISTKVSKKAVIRNRLKRQIAAALYELLPKLAPEWRLVVVVKPTAAQQECGSKQFLQELEQLLVKAEVINGHS
>NC_019678.1|WP_015116366.1|229044_229437_-|PH-domain-containing-protein
MGIREEVYYEGGPHIGDLIIGILIGLTIVGLPLAVGAFVRALWLRYRITDRRISVTGGWMGRDRSDIIYSEIVKIAKVPRGIGLWGDMVLTLRDGSRLELRAVPKFRETYNYISQQVAARNPKFADAAKQ
>NC_019678.1|WP_015116365.1|227637_228792_-|membrane-protein-insertase-YidC
MDFGIGFLSNNVMLPIIDLFYSIVPSYGLAIIALTLIIRFSLYPLSAGSIRNMRKMKIVQPVMQKRMAEVKEKYKDDPQKQQEEMMSVQKEFGNPLAGCAPLILQMPVLLALFATLRGSPFATANYNVNLQILPSEQIERIQPAAFATKPSSIYVDEGERIKVAAILPGGNKLAVGEHTKLQYQTVDGKPFEEILEQHPDNQSKLLPQWKITKGAERISVDAEGNIEALQPGDVTIQGNIPGLAADTGFLFIDALGRVGAFDDDGTIHWDIVSMIGLFGVSLYVSQLLNTQGNAGGGNSQQDTVNKITPILFSGMFLFFPLPAGVLMYMVIGNIFQTLQTYILSKEALPEEVQKIVDAQEKEALSAEAKALPFEPKSTKKKATS
>NC_019678.1|WP_015116364.1|227122_227638_-|RNA-binding-protein
MMSDTRMQRGEQWLKELLQLSGFSVEIKGDKEENTLGEKDPLSLNSYWLTIEESNLTENQIQVLIGRDGKALDAMQYLANSILNLNQESNEQASYTVELNGYRVRRLAEIRNMIEEVVDRVRNTGQQVEVKSLSSAERRQVHTLLKGFEDLESFSQGKEPHRHLVVRPFSW
>NC_019678.1|WP_015116363.1|226522_227026_-|hypothetical-protein
MDAIYIPQLAQASKPIEDIEVKEFLPELQTLTPVRGNLRVEHRGNFLEVTAKAETIMTLTCNRCLQQYNHRVLVNTSEIIWLDEVAEVEEEFLAEREVALDELVETLSPYGYFHPSMWLYEQMCLEIPQRQLCDKDCPGIEQNRDAKPEDKPIDSRWASLQSLKKQL
>NC_019678.1|WP_015116362.1|225797_226352_+|hypothetical-protein
MKNKLLFSGAIIIALFNLTGCGQDNANTETLAPVETTSQNNQETQISQPLSTTAETPEVPVSTSKPAKTASNQTNNSATYDDNRGNRTIRIKFDIGTSSKTVKDSVVRGTRDIYLLGANTGQQMNLNIASLEDNAVFDVISPNGQILQQETKNWSGKLPQNGDYQIVVGGTRGNATYELATEIK
>NC_019678.1|WP_015116372.1|233552_234953_+|NAD(P)(+)-transhydrogenase-(Re/Si-specific)-subunit-beta
MSDFLPTGIQITYLVAASLFILGLKKLGSPATARNGNVMAAVGMLLAIVATLLNQQVLNYQMILLGLAIGSAIGAIAAYTVQMTQMPQMVGLLNGLGGSASALVAVAEFWRLLDSNQPIGLDVNISMLLDVFIGGITFTGSTIAFAKLQGILKGSPITYPLQQPFNILLLVGYVVGSGFLIVNPYNLPIFLGIVGISLLLGVLFVIPIGGGDMPVVISLLNSLSGLAAAAAGFVVMNNMLIIAGALVGASGLILTQIMCKAMNRSLFSVLFGAFGGATGGGAAGGGTTEGTVRSVDPEECAMMLGYARSVVIVPGYGMAVAQAQHGVRELADQLERMGVDVKYAIHPVAGRMPGHMNVLLAEANVPYEQLQDMEDVNPQFEQTDVALIIGANDVVNPAAKSDQNSPIYGMPILEVDRAKQAIVIKRGMSKGFAGVDNGLFYKDKTSMLFGSAKDMVGKLVAEVKQL
>NC_019678.1|WP_015116373.1|235518_238356_+|tetratricopeptide-repeat-protein
MLQRKYGEIVDRQKYVEERLFGIINDEDNSINAVVLYGQSGIGKSSISKSLRTKITQHLSNSTVAVLGEENLNNCVRANPVNAILLKLRNKLLKDNSDLSCFDIAYLLYGALANNSTDVDLSTKVIQKSQVLQIIEIVKKGLYQFPLLLEATKCLGNYQSQQKWQPEFDGSQIYAALSWFFIQQNQEIRQWWKLKGSQNLQELKDCASLSDILKLLPLFLGRDLQAHFQNTQQKAVVFIDNYEYLNTYQENHNWLKDIIPLIPSILWVIFAEKTVDATTNTQHIPIPNLTNAESQVIIQKLGVENDEIAQQIIQASEGIPLYLHLGIETYLNLTKQKAAQVKNIASNISEILPKLSATWDWYERRIWQVLSNCRSWDEVLFAKLMSQFDIASCDWICDCWDKLLHRVVKSPFVESNPEGWSLHPIVGEYLHRNQPDNLQQSVNNWLFEYNQAEYQQSELQLSALIKLLEYGLKSRQQQKVVSWFLAKVKLQQKAGKHDFTVFALKILLRYQNNALAFSLLGESLYALGDYQQAVTALQTAQKLWEAEKLQDSLAFSNVQLQLAACYVKLQCTSDANDAAKKALAIRTTQLNQNSLEIAEVLNLQALIAVIEGFHVRALELTQQALQIFASHQNVEIKLAQTKFTLGWLNAIAKNYHAAEKLFKQVLNDIADENHPLAIYCHGMLGNIYQNIGYFAYHQAYEEYNKSLEIAEINFGLTHPRTLQLIAAIINFSRIRGEYDTVDILTQRRHANMEISNFEENPAVADRLNKIGCLLLQQGKYAFSEHLLQQALQINCRYLSQQHPQTAETFHNLGLIYKNQKRYYTAEVYFKQALQIRCATFGKKHPITANSINSLAALYCCMEKYQQAEPLLQQALEICYKNFGEMHPHTATTLNNLAQMYQCLGLSKKAEPIFHQALDICQQVLGDNHVYTKIVESNLSRLQEKN
>NC_019678.1|WP_015116376.1|238811_238901_-|cytochrome-b6-f-complex-subunit-PetN
MAILTLGWVTLLVVFTWSIAMVVWGRNGL
>NC_019678.1|WP_015116377.1|239016_239487_+|hypothetical-protein
MKGTFNPDLMAERLESFKAGIVSALSFSLVFILASIFNQFLLKEYFRQFYTDSVITLNWHLLISAGFAGFSGFLFGATYRYIIREDKNPHLKEGSVFAFGLARGLAQVDMGLNFSDSVFPLTVLASESITGFAIAAFTLDWAIKFGWVKPFVGSRE
>NC_019678.1|WP_015116378.1|239512_240058_+|exonuclease-domain-containing-protein
MSSYFLIVDVEATCCNDGSIPKEEMEIIEIGAVMLNRSTWAIDSEYQQFIKPVRHPKLTSFCTELTSITQKNLEPAPTFPEVIPQFKKWIDSYPKNIFCSWGNYDKNQFILDCSFHHLPYPFGTEHRNIKKEFSLYSDNKKKRFGVMQALQYLGLEFQGTHHRGIDDARNIAAIVKYINQD
>NC_019678.1|WP_015116379.1|240274_241270_-|pyrroloquinoline-quinone-(coenzyme-PQQ)-biosynthesis-protein-C
MTLTKIVFQQPIFKSQVLFDFKEDEIIIRDANQAFSIASPPEYYQAIAKLLRLLQIGGLSPKQLSEACPDIQEEIPELLANFDNRSLLIETQKKVPAAGMSGSQFYRELWRFVERLKLQFTSSPFFGKMADGTITKNQLIGYALESYHVTHLCPKLLAPALANYESNSVDKLLQEFFASELHHDRLIAKSLRSVGISDEEIQKMQPLPSTFAICSSLAMFAKQHPLSFKTALMLFEQDEPLFHEYFKKQSQALELPRDFYQPILLHAGINEDGGHEDITGVLLAEISYITPSEQLTVKKNMANLMELIVLRSYEIVDYYGNQNNIIPRCFV
>NC_019678.1|WP_015116380.1|241320_242361_-|hypothetical-protein
MLDNISVTDAKLPEFEGKQHKLPLPQYPKLAASVNQYQNQIIFSQQGRDFAFQVNSQSEKALHKVLTMMDGKNSLTKLQQTFSPSNPEAINTLLRYLDDKKLLDDADDIKINSGLDVLLELENLSYELVKNKSTQNQLILIAPDISNLSINIIYGFAIEAYHLLAHQAYIDASSLSFQGSTVIRQLINQLYCQEYGQDKFLIEALNSIGIDNEDLIDTMPLPQTTAMCNSLAYWASFDTLFYFSILGFLANQNLTNFTYYLQACESLKVNYSFIESIQNLVNHFQKSKLDNISHKIFQQISHIDEQTKQRLQRQVYLFIETYTNYHNTIFYYYSSSTSLLRRVSDI
>NC_019678.1|WP_015116381.1|242496_242799_-|hypothetical-protein
MAKLQINDVKLDGAELFNDSETFLNELQDGEIEQVVGGLTRVAPEHVTTTAYFPDKPYRTVYIPKEPIHPRLPVHPKEPVHPRQPIKFPYFPHPQTPVIL
>NC_019678.1|WP_015116382.1|242927_243224_-|hypothetical-protein
MAKIQIKDVNLDGAELFNDSETFLNELQDGEIEQVVGGKTLVAKDRLAVYTVHYPDEPIHPGRPPVHPGRPVHPIKPVHPRKPIKFPHFPHPYTPVIL
>NC_019678.1|WP_015116383.1|243472_243751_-|hypothetical-protein
MAKIQINDVKLGDTELLNDAETFLNELENGEMEQVIGGKTISLDDYEFYKNKKFDFPKRLHPIKPIDFPEPNLPKLPKHPGVIKIPYEPVIL

Crispr_ID: NC_019678_3

• CRISPR_ID: NC_019678_3
• CRISPR_location: 276315-276421
• CRISPR_type: TypeI-D
• Repeat_type: I-D,II-B
• Spacer_info: 1 spacers
• Cas_protein_info: cas3,WYL,cas10d,csc2gr7,csc1gr5,cas6,cas4,cas1,cas2

Consensus repeat of NC_019678_3

Consensus_repeat	Method
CGAGTTTCAATCCCTGATAGGGATT	CRISPRCasFinder

spacers of NC_019678_3

>3.1|276340|57|NC_019678|CRISPRCasFinder
AAGATTTTTGTTGCTTGAGGTGCAATTAGGAGAGGAGTATAAAACTATCGAATAGCT

CRISPR arrays and Neighbor proteins around NC_019678_3

CRISPR arrays

The CRISPR arrays of NC_019678_3

>merge|NC_019678|3|276315-276421|CRISPRCasFinder
CGAGTTTCAATCCCTGATAGGGATTAAGATTTTTGTTGCTTGAGGTGCAATTAGGAGAGGAGTATAAAACTATCGAATAGCTCGTGTTTCAATCCCTGATAGGGATT

>NC_019678|3|3|276315-276421|CRISPRCasFinder
CGAGTTTCAATCCCTGATAGGGATT	AAGATTTTTGTTGCTTGAGGTGCAATTAGGAGAGGAGTATAAAACTATCGAATAGCT
CGTGTTTCAATCCCTGATAGGGATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015116404.1|265368_267453_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015116412.1|280506_281550_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	gnl|CDD|375747
NC_019678.1|WP_015116409.1|273164_274037_-|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl|CDD|379100
NC_019678.1|WP_015116415.1|283597_284191_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|187768
NC_019678.1|WP_015116410.1|274136_276314_+|type-I-D-CRISPR-associated-helicase-Cas3'	cas3	cd09710_cas3_CAS-I-D	gnl|CDD|187841
NC_019678.1|WP_015116411.1|276942_280356_+|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	cas10d	cd09712_cas10d_CAS-I-D	gnl|CDD|274469
NC_019678.1|WP_044290703.1|272228_273098_+|fructosamine-kinase-family-protein	unknown	unknown	gnl|CDD|367711
NC_019678.1|WP_015116416.1|286459_286732_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NC_019678.1|WP_083894029.1|284290_285088_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NC_019678.1|WP_015116414.1|282517_283360_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl|CDD|227838
NC_019678.1|WP_015116403.1|264299_265199_+|Hsp33-family-molecular-chaperone-HslO	unknown	unknown	gnl|CDD|234643
NC_019678.1|WP_015116406.1|269681_270320_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015116405.1|267950_269456_-|C-3',4'-desaturase-CrtD	unknown	unknown	gnl|CDD|274272
NC_019678.1|WP_015116418.1|292224_292686_+|response-regulator	unknown	unknown	gnl|CDD|381100
NC_019678.1|WP_015116401.1|262747_263404_+|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|224331
NC_019678.1|WP_015116419.1|292963_294088_-|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl|CDD|223715
NC_019678.1|WP_015116413.1|281552_282284_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	gnl|CDD|187842
NC_019678.1|WP_015116402.1|263648_264038_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015116407.1|270758_272042_+|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NC_019678.1|WP_015116417.1|291146_291347_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019678.1|WP_015116411.1|276942_280356_+|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	cas10d	cd09712_cas10d_CAS-I-D	2.5e-304	1006.4	1.8
NC_019678.1|WP_015116409.1|273164_274037_-|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	6e-15	50.4	1.4
NC_019678.1|WP_015116415.1|283597_284191_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	2.9e-51	168.9	2.3
NC_019678.1|WP_015116410.1|274136_276314_+|type-I-D-CRISPR-associated-helicase-Cas3'	cas3	cd09710_cas3_CAS-I-D	8.4e-124	407.8	0.0
NC_019678.1|WP_083894029.1|284290_285088_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	1.2e-86	285.4	0.0
NC_019678.1|WP_015116412.1|280506_281550_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	5.8e-110	361.7	0.0
NC_019678.1|WP_015116413.1|281552_282284_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	2.6e-76	250.6	2.4
NC_019678.1|WP_015116416.1|286459_286732_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	8e-33	107.3	0.4
NC_019678.1|WP_015116414.1|282517_283360_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	3.5e-68	224.7	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015116411.1|276942_280356_+|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	gnl|CDD|274469	TIGR03174, cas_Csc3, CRISPR type I-D/CYANO-associated protein Csc3/Cas10d. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family is a CRISPR-associated (Cas) family strictly associated with the Cyano subtype of CRISPR/Cas locus, found in several species of Cyanobacteria and several archaeal species. This family is designated Csc3 for CRISPR/Cas Subtype Cyano protein 3, as it is often the third gene upstream of the core cas genes, cas3-cas4-cas1-cas2.	0
NC_019678.1|WP_015116409.1|273164_274037_-|WYL-domain-containing-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	2.23702e-07
NC_019678.1|WP_015116415.1|283597_284191_+|CRISPR-associated-protein-Cas4	gnl|CDD|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	2.5553e-56
NC_019678.1|WP_015116410.1|274136_276314_+|type-I-D-CRISPR-associated-helicase-Cas3'	gnl|CDD|187841	cd09710, Cas3_I-D, CRISPR/Cas system-associated protein Cas3; Distinct diverged subfamily of Cas3 helicase domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Diverged DNA helicase Cas3'; signature gene for Type I and subtype I-D.	7.75119e-137
NC_019678.1|WP_083894029.1|284290_285088_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	2.01111e-114
NC_019678.1|WP_015116412.1|280506_281550_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2	gnl|CDD|375747	pfam18320, Csc2, Csc2 Crispr. The Csc2 Crispr family of proteins forms a core RNA recognition motif-like domain, flanked by three peripheral insertion domains: a lid domain, a Zinc-binding domain and a helical domain. The CRISPR-Cas system is possibly a mechanism of defence against invading pathogens and plasmids that functions analogously to the RNA interference (RNAi) systems in eukaryotes.	8.18923e-173
NC_019678.1|WP_015116416.1|286459_286732_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.06857e-36
NC_019678.1|WP_015116414.1|282517_283360_+|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	9.77235e-54
NC_019678.1|WP_015116403.1|264299_265199_+|Hsp33-family-molecular-chaperone-HslO	gnl|CDD|234643	PRK00114, hslO, Hsp33 family molecular chaperone HslO.	3.6293e-153
NC_019678.1|WP_044290703.1|272228_273098_+|fructosamine-kinase-family-protein	gnl|CDD|367711	pfam03881, Fructosamin_kin, Fructosamine kinase. This family includes eukaryotic fructosamine-3-kinase enzymes. The family also includes bacterial members that have not been characterized but probably have a similar or identical function.	7.12701e-161
NC_019678.1|WP_015116405.1|267950_269456_-|C-3',4'-desaturase-CrtD	gnl|CDD|274272	TIGR02733, similar_to_to_phytoene_dehydrogenase, C-3',4' desaturase CrtD. Members of this family are slr1293, a carotenoid biosynthesis protein which was shown to be the C-3',4' desaturase (CrtD) of myxoxanthophyll biosynthesis in Synechocystis sp. strain PCC 6803, and close homologs (presumed to be functionally equivalent) from other cyanobacteria, where myxoxanthophyll biosynthesis is either known or expected. This enzyme can act on neurosporene and so presumably catalyzes the first step that is committed to myxoxanthophyll. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_019678.1|WP_015116418.1|292224_292686_+|response-regulator	gnl|CDD|381100	cd17548, REC_DivK-like, phosphoacceptor receiver (REC) domain of DivK and similar proteins. Caulobacter crescentus DivK is an essential response regulator that is involved in the complex phosphorelay pathways controlling both cell division and motility. It localizes cell cycle regulators to specific poles of the cell during division. DivK contains a stand-alone REC domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.58657e-31
NC_019678.1|WP_015116401.1|262747_263404_+|HEAT-repeat-domain-containing-protein	gnl|CDD|224331	COG1413, COG1413, FOG: HEAT repeat [Energy production and conversion].	3.69747e-21
NC_019678.1|WP_015116419.1|292963_294088_-|hybrid-sensor-histidine-kinase/response-regulator	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.05137e-49
NC_019678.1|WP_015116413.1|281552_282284_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1	gnl|CDD|187842	cd09711, Csc1_I-D, CRISPR/Cas system-associated protein Csc1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas5 ortholog; also known as CasA/Cse1 family.	1.57713e-78
NC_019678.1|WP_015116407.1|270758_272042_+|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	2.3048e-104

Protein sequences

>NC_019678.1|WP_015116410.1|274136_276314_+|type-I-D-CRISPR-associated-helicase-Cas3'
MSNYRIQLKSIYSCPADEVPEDVNLPKGWMLAWHQLETLKALRNADIDVVINTAMTGDGKSLAAYLQVLQENCCAIGLYPTNELARDQETQTKGYIETFQPRNEPRVTRLSGADLEIYAENEGLKKSSAISTRTHQSEVVLTNPDIFHYLHRGAYLTPDDSPDKLWGRIDKDFDLFILDEFHVFAAPQIASVINTMLLIKFTNRRKKFLFLSATPDDNLIGKLQKAGFRCKVINPLEENKYRFPDTLAESLELKNKNWRQVSRPISLNFISLEPTFKASENWLRENSSLILEYFQNHPGSKGAIILNSIAAVKRLVPFFEELLQPSNLSVGENTGLSGRTQKEFSLSADLVLGTSTIDVGVDFKINFLIFESADAGNFIQRLGRLGRHDGYEKDGEDIKFDNFTAYALIPKFLVERLFKEDSPPLQENGIYNRPFFHNTIIEKYRQINDFSGYYRRWAGVQSVQLTWKLKHKTVKQQYSETVKEFSKTCESVFDTKLNSVFGCIKGWEKTWNELSGTKGNPIAEDAASFRGSSSLQCGIYDLTEQNEADRFKTYDLPGIVANLDIEMWTEAGFIRTLKDTASRINQPIPKGRFAHCLGFMKLRSYREERLNWKFIYSGDLQPIADAWKVQVLKGIEIWQPDNPWIGEINKRLKKKGLVCYVLRNPVTEIRMRLRLPMHFQIYPICDKYSINDATAPYSIAFSQSGLLLDTLAYTFKGKGDETWIY
>NC_019678.1|WP_015116409.1|273164_274037_-|WYL-domain-containing-protein
MSRKGKSITLSVSERDKAELETLALEFGCNWGERPNISKLVESIARRQLIVAPNNDWTNERIKALETARKALVDLGKTDEAKQIAELLKSRSELTLPFREEIETFLNHPLPAWRQQVDNLIHRQQPFRLSYQDAAERVWSYTVLHARIVPIEKRQYLLCRAEESEGNQDVEGLRHNWTLRLDRIQEAAVVSIDKPWENDLERIAVEFHLLSRLAFAYQRKTEDIFVSELEAEPPIKRVVRNISGTFWFFREITRYGKDCEIVSPEAVRSQFKQNLKSLCQAYDLEIKEED
>NC_019678.1|WP_044290703.1|272228_273098_+|fructosamine-kinase-family-protein
MWTEINAQISQATGENFQTQQRRSVSGGCINQGYSVSDGKRTFFVKLNQAFQVAMFEAEALGVKQMYDTNTIRVPKPICYGVAGNSCYIVLEWLEIGRGDSKASEEMGRKLAQMHKKSLSEKFGWDMNNTIGSTPQINTWTDDWVEFWTKHRLGYQFELGKRRGGSFPQASELLNAIPELLAGHEVQPSLVHGDLWGGNAGFTVDGEPIIFDPATYFGDREVDIAMTEVFGGFSTAFYQGYNEVFPLDHGYEKRKTLYNLYHILNHFNLFGGGYGSQANGMIGRILSNK
>NC_019678.1|WP_015116407.1|270758_272042_+|insulinase-family-protein
MSSTLLKFPRLNAPKLQHLPNGLTIVAEQMPVEAVNLNLWVDIGSTFESDAINGMAHFLEHMIFKGTKRLASGEFERRIEERGAVTNAATSQDYTHYYVTAAPKDFAELAPLQIDIVMNACIPEEAFERERLVVLEEIRRSEDSPQRRTFSNAMETAFENLPYRRSVLGPEAVISQLKVEQMRSFHAQNYQPKSVTAVAVGNLPEEELIEIIAKGFADIEKRDLGKIETQDINLLQSEPAFTEIVRKEFVDENLQQARLIMLWRVPGLMQLNQTYGLDVLSAILGHGRTSRLWRDLREERELVNYISVSNMTNQLQGTFLIAAHCEIENLAAVEEAIVQHIRKIQTQIEESEIARVRKRVANRFIFANERPSDRANLYGYYQTLVGDLEPAFDFPYHIQSQDRETLIQAARTYLSPDAYGVVVMKPN
>NC_019678.1|WP_015116406.1|269681_270320_-|hypothetical-protein
MKILPLIAIFTTINIATPATAQLIPPTPVKINNPSIPDVRVIRNGTTIRIYNGKIIKNIRAKSLKVRVLDSQTCQGKQVQRQTLSGKRFLTQTIEVDKQTGNLAVGVLLQDCFKQKISAAFILQPEPNWNNYIIHRVPIPGARKINNRFSTYPLRNIKGLGFVDGNLIIKYANSDNSEAMLVYTSSNKPIGKYAGCVVTKQSKNNNICPHFN
>NC_019678.1|WP_015116405.1|267950_269456_-|C-3',4'-desaturase-CrtD
MSNGKGKSRIVVVGAGIGGLTAGALLANKGYEVLILDQALVPGGCASTFKRKGFTFDVGATQVAGLEPGGIHHRIFSELNIALPEATPCDPACAVYLPGETTPINVWRNPQKWHEERLRQFPGSEPFWNLLSTLFKASWRFQARDPVLPPRNWWDLLQLTTAVRPDTLVTVPYTLSTVGDALRFTGQGDNHRLRTFLDLQLKLYSQVNAEETALLYAATALSVSQEPQGLYHLEGSMQVLSDRLVESLERDGGKLLMRHTVEHVKVENNQVSAVVIRNQKTGEVWTERTNHVVANVTVQNLVQLLGEKAPKGYKKRVENLPPSSGAFVIYLGVDESAIPHGCPPHLQFLYDAKRPIGENNSLFVSVSRTGDGRAPTGKATIIASSFVDADRWWNLDNYDALKEQFTQEAISHLAKFFYLKPETIVHVEAATPRTFYNFTARDKGIVGGIGQRVPTFGPFGFANRTPINNLWLVGDSTHPGEGTAGVSYSALTVLRQIIANT
>NC_019678.1|WP_015116404.1|265368_267453_+|hypothetical-protein
MAERDIPDGWSSARRTQSDDMTRLFNTEKSADGKYGFPGTGSNSKSVSSKNKSNSKKLTLKGHSKQNVPAHSSSGKLPRWLTSWVLWAFLLAFVPGTIGFMAMAILLKLPSAPNCPSIFWPLASASVRMHCAQVAASKETVKDLLQAIDLVKNLPQNHPLRSEIDRNVEDWSRNVLQLADQSFQAGRLEEAIEIARKIPEDVSASKLVEDQIDSWKLTWSKASDIYEKAEGEMREQRWQSAFMQSAKLLRLNNKFWASTKYEELNKLILGAKEDGQKLAKAESLSKSKNVDQILKAIKLAQSIGKNSYVYKKAQEAIPDFGMRILELAENKLEQRDADEAIYIAQRIPPISEIEPETTDFIALAEAQRNAWTGTISGLEAAIASAQQIDSNRPIYQKAQKLIATWQLEIEDVSRLERARTLASQGSIGDLSAAIAEAKMIPRNNPRAKEARKEINSWASQVQTIEDRPYLERAEELALFGDVSSLKAAIAEASRIRRGRSLYREARKKIASWSRRVQRIEDQPYLDQARSLANSGDLGAAIQTAKQIRSGRVLSRQAQRDINEWQSEVSARSNWRRAREVALGGTPKALSQAIRLARRVPRGTGLRSDARIAMDQWSQQLFDIARTQSQSDIVRAIETAKLVPRGTQAYGQAREQIRTWQDYLNPPAPEPEPEPEVVQPSVPQAQPEPITGNTL
>NC_019678.1|WP_015116403.1|264299_265199_+|Hsp33-family-molecular-chaperone-HslO
MADQLIRATAADGGIRAVGAITTKLTSVARERHNLSYVATAALGRTMTAGLLMASGMKRVGSRVNVRIKGDGPLGGILVDAGLDGTVRGYVGNPKVELPPNPQGKLDVGGAVGKGFLYVVRDVGFGYPYSSTVELVSGEVGEDIAHYLLSSEQTPSAIVLGVFVGAQGVTASGGLLVQILPKAARDDALVETLESRVAALQGFTPLLQAGKNLTEILQDILGDMGLNIFPESQMLRFNCGCSFDRMLGALKILGEAELQDMISKDDGAEATCDFCGEVYQANSKQLAQLIADIQAESSV
>NC_019678.1|WP_015116402.1|263648_264038_-|hypothetical-protein
MLGSFQTSQLRIEVDATQQVITESILHPMQLGKWLPSGKFPSGSMPEQLHSGFEFTTHIGPLSIHHQVDVASANSLRLLLSQGIDGFHEWYWGEGWVQSRLEGISLLPLSLGQTASLFSLRQHLKSKQS
>NC_019678.1|WP_015116401.1|262747_263404_+|HEAT-repeat-domain-containing-protein
MSITPDTVKKKLESEDLGDRLRGVNEIRQLEPAIGFELVQSAITDKNARVRYSAASQFDTLGTQDLDKSLDLLRGLLQDPEADVQAAAADCLGGLKLVAAFDDLQQLYQSTEEWIVKLSVVAALGELGEPRGFDLLKQALSEDNDLVKTAAISSMGELGNPQAVSILESYASNSDWQIRYRVAQALNRLGTEQAKPILENLANDEVEAVAEEAKKNIS
>NC_019678.1|WP_015116411.1|276942_280356_+|type-I-D-CRISPR-associated-protein-Cas10d/Csc3
MTKKINDLEEHKQLSLFDIEDNSQSEDSDYDWLDDEDVDFGFETSDRTVETAQELLTYKLLREAIEAQNPDDEVMADFAKYVLPNLLQIAIGVTAKGGKYFDKLDREKAAAGKAKVRRDNAADQSLNTHLLNGLFPANLIERRLVKLNTTVMRVVGEVERRLLVAGFILHDFEKFPDVPDDCRKLAIEEHRRIIDQKVRQLGLDKFINPSQSEAYQEYLDDLLCMAYNAQRRWDTNWNFSEFGLNPQLRDRTLRCLSELTCLADSLASIIKHPQDAQSYKFKELLSALSDGELQFTYHSIAENRGVLTNVVNNALIAAHTSLNTENNICYEPLLYLPTGVIYLASRDAPAISQEDLPDRVISTIKSLCASQLRLRQTGFGRDGKGMKYADYYNLFFDDVALMQVGLDATLRILHPKKDSVAKSRSDNLVKFQEKDVLPSDFDLKFSDDIRIDQIAEFGDLIARKIWGEKVKQIESLRKKDKKLPELPQLDLIHKVAEFWNLTEYLPEVKAIQRINESLKENKLKGNTGGVPYEWYYLAAKYLEHNPGIEDIREVCQPVITFVQSLIEPIVSQYQIADGWDDLRLWVQRVIMLPGSNREANENQVETFLDELSNYNTAKKSGRGKQLICSISHSAYTVTEQMESAVLFTPQVYTNKQMLGGSNAKRNISSIAGVEMMLRQILMNQTQAVGKRFEDGKYRYLYFYPTYYFTPETNKFLQIAYSGIAQTRFDTSIRNHFIPKNLQANLGKDKYQSVDSFLIDEDLQSQKNLPEDDPNYKKDRTFKLSYPEDQPLTFYFMALPPGRDSSDTESWIMPSWLAFAFPMILDVKTVVSESPIPPFNDGAEFEESVFLDSAPHAFRALVKQDKFRLDYILEGWQDNNKTYSAPLNVLTAAYAIHLDVNAKQGKSGYDANWGKFTELAKDFETSPLYVFSYLNRWVRKQGVETARIEKIKLYAYDFYPCFDAYVKYDNIQEKLIVESESSLCHTQKLTELYRRFYRANKKYNPKSNAVLKPIDIAAETILKAELSVHTGECLVLVVAAEVFKLMDRVHASTAEGRWVFNHKEREEERQAVLEFARYFVEDIFEKSFAGDRARLAGRQINLIRDTCEFLYRLENDKENQLQGNDSKKENDSETLISS
>NC_019678.1|WP_015116412.1|280506_281550_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2
MTFLKSIDSKLFHTEIPYKPMGKYVHFLTIRVTESYPLFQTDGELNKSRVRAGKKDKNTISRLSMFKRKQSTPERLVGRELMRNYGLVKDEECEYNVKFAMDNPDCIIYGFAIGDSGSEKSKVVVDTAFSITPFDESHETFTLNAPFENGTMTSKGENGSKPGEVTSRINQQDHIRPQVFFPSIVTLKDPTEASFLYVLNNILRTRHYGAQTTRTGRVRNELIGVIFADGEITSNLRWTQAIYDEMKANNSINSPEPLDEDDVITAAKTAIESQMAEEFIVHQDYLNDEFAALLKEVKAITANEDELKKLLKKADVEAKEYAKVHIKVKSKDKDKNKDKNKETAANS
>NC_019678.1|WP_015116413.1|281552_282284_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1
MTIIYCCQLELHDSVYFATREIGRLYETEPVIHNYALCYALGLVDSEIYATTVSEEHSYRYFCPEQVPKYEEHLTPLNQQGIYVTPAHSIHHTSVLNTWKYANNNYHVEMQKTQKNIPSFGRAKEIAPESQFEFFIISKNDIELKGKLPKWIRLGKWMSKAEVEIQQVAKLESKTGDFTFPYPLNPLDVMFTNQVISYDVVNMPPVSLIQNVTITKGEFFQFENPFTSQKLKLPAKMAYRFKG
>NC_019678.1|WP_015116414.1|282517_283360_+|CRISPR-associated-endoribonuclease-Cas6
MPHSLILNLTPKSPIYPQFLTGRHLHALFLTLVSSVDKELGTHLHDSKADKAFTLSPLQISKRNSPIAKGSKRGSILKSQHQEAISTGTPCWWRISLLDDALFGKLTQLWLNLNPQQPWHLGSADLYITSIQGTPQSTQPWANACSYNQLYEQASDSERIISVNFATPTAWRQGKYDSTLPTRESVFKSLLSRWNKYSGIEFENLNFDAIFPSFINIHTEIVPDSRSKFIGIVGEVSYRIMGDVEAIQIKQINALADFALYCGIGRKTTMGMGMGRRVRS
>NC_019678.1|WP_015116415.1|283597_284191_+|CRISPR-associated-protein-Cas4
MNNTDYITIASLNQYSYCPHRCWRMFCLGEFTDNQYTIEGTSLHERVHTVSENNQEETWQIRAIWLKSEKYKLIGKSDLIELENDEWYPVEYKRGKKGEWDNDELQVCAQALCLEEMTGKDITTGYIYYAQNNKRQLVEINDDLREETIATIANVTQLLETGKMPPAIYSKRCKGCSLYSQCLPMAVDKVKRYQEAQ
>NC_019678.1|WP_083894029.1|284290_285088_+|CRISPR-associated-endonuclease-Cas1
MGTVYITQMDSFVGKVDERLTVKFEKNKILDVPLIKVDGVVVLGRATISPAVVYELLERHIPLTFLTETGRYLGRLEPEVTKNLFLRKAQWRATENSPTSVGAVQSFVRGKLKNYRNVMVRRQRESAKLDLSKNITHLENAIAPIDTTENIDSLRGLEGAGSAAYFSSFDQMIRTTEFKFTRRVRRPPTDPVNSLLSFGYSLLRHDVQGAVNIVGFDPYLGYLHCDRYGRPSLALDLMEEFRPLVVDAMVLSTLNKYLCKINCIF
>NC_019678.1|WP_015116416.1|286459_286732_+|CRISPR-associated-endonuclease-Cas2
MNVVVSYDISEDKRRTKIHKVLKSYGQWVQYSIFECQLTDTQYARLRSRLNKLIKSDTDSIRFYFLCACCFGKVERIGGEQPRDDSIFFA
>NC_019678.1|WP_015116417.1|291146_291347_-|hypothetical-protein
MIHIRFEGRSYDVEQSKLGLEQNMSDTDIKQRLAQHFDVAVNSFQYYVIDRRPNGDLIIRPEAVYG
>NC_019678.1|WP_015116418.1|292224_292686_+|response-regulator
MNLANTFSMDKNHTCEPPLVLVVEDNEDNLFLISHILESLGCRVIFQRVGSEATVILAKEHHPDLILLDIVLPDVSGIDILQLLRQEPLTCDLPAIAVTALATEQNRENIIRAGFNNYIIKPYLIEELEEMIFPYICGKLNSSSKYVVGQDKL
>NC_019678.1|WP_015116419.1|292963_294088_-|hybrid-sensor-histidine-kinase/response-regulator
MSIQDSQVLDRILAVDDIPDNLFLVQALLESEGYEVKLVTDGGTAIKEVKKTPPSLILLDVMMPEIDGYEVTRRIRSITDDNYIPILLVTAFDDVSVVEGLDAGADDFIRKPFDTDELLARVRSLLRLKHSIDAQKQMARQREDFVSRLTHDLRTPLVAADRMLNLFLQETFCKISPEMKKAIAAMVRSNNNLLEMVNTLLEVSRFEAGKKTMNFESCSMYSIVEEVVQELSPLAEERDLQLEFKNNLTEESKDKSAVNGDRLELRRVVSNLIGNAIKFTDEGQIEVRLSEFTSNAGEEWVKVDVEDTGYGIAEEDKTTIFERFRSGKNKRSGSGLGLHLSNRIAETHNAKIEFSSELGKGSIFTVVLPKASED

Crispr_ID: NC_019678_4

• CRISPR_ID: NC_019678_4
• CRISPR_location: 286960-291024
• CRISPR_type: TypeI-D
• Repeat_type: I-D,II-B
• Spacer_info: 56 spacers
• Cas_protein_info: cas2,cas1,cas4,cas6,csc1gr5,csc2gr7,cas10d,cas3,WYL

Consensus repeat of NC_019678_4

Consensus_repeat	Method
GTTGAAATCAACTTAAATCCCTATCAGGG----------ATTGAAAC	PILER-CR
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CRISPRCasFinder
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CRT
GTTGAAATCAACTTAAATCCCTATCAGGG----------ATTGAAA	PILER-CR

spacers of NC_019678_4

>4.1|286997|36|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TGGGAGAAAGTAAGAAAGCACGGTAAAGCGACCCGC
>4.2|287070|32|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTGCTACCTGCATCTTTATTATCGGGCTTTAT
>4.3|287139|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CTAGATAGGTAGTACCTACTGCTAAAGCTTGCCAA
>4.4|287211|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTATTAATCTGAATAACCTTCCTTGAAGTGTTGAG
>4.5|287283|38|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTATCTGGACCTTTTTGCCTGGAATACTCATACTCAAA
>4.6|287358|36|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TGAGTATATCTGACTCAAAAAGGGCAGATTCAAGAA
>4.7|287431|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AAAAAAAGACTATAAATCCTCAAATAAGTTGAGTT
>4.8|287503|38|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTATATCTACAACTTTTTTCTTCTCTTTCTATGAAAAT
>4.9|287578|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTAACAACTCTAAATACATCATACATTGTCTCA
>4.10|287648|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AAATATATGAATCACAACAAACACAAAAAAGGAAA
>4.11|287720|36|NC_019678|PILER-CR,CRISPRCasFinder,CRT
ATCCTATTGATTTACATGTAAATAATGATAGGAAAA
>4.12|287793|32|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CTCTAACAGATCTTTTTCGTAAATATTCCAAT
>4.13|287862|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AGATTCCATCCCCGCTTCGATAGCGCTCCAGTTT
>4.14|287933|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AATCATGGATTAAATTATTTAATTGGCGCATACAA
>4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AAAATAAAAATATGAAAAAGAACAAGAAAAATCA
>4.16|288076|36|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GCAAAATATATTTCTGGAAGATTTGCTTCGGAAATT
>4.17|288149|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTAGCAGATAAAAATAGTACACAAGCAGAAAAAA
>4.18|288220|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CAAGCTTTTTACCGTTTGTAACACCACTAGAACC
>4.19|288291|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TGAGAAACACGATGCATTCTGCTTGAATAAAAAGA
>4.20|288363|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
ATCCGCCAGTAATTTTACATTTATCTGCCAGTGAT
>4.21|288435|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AAAGAATTTAGCACTACGGCTGCACCTGCTGAAT
>4.22|288506|37|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TACTTTACCTTTCTTTAAAAGCCATTCCCACATCAAT
>4.23|288580|36|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CTGGAAAATACTAGAATCATAGGCTTCAAACAAATT
>4.24|288653|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CTCAATCTTGAAATCTTCTAAGCCTGAGCCTATGA
>4.25|288725|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CAACATCTAAGGAATCCGTACAGCTTTGACTAC
>4.26|288795|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTGAAGCCTTATAGAAGCTTTTAATTGCAAGTTT
>4.27|288866|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CTATTGAGATTAATGAAACTTGGGAAAATAACCT
>4.28|288937|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AAATTGCATATTTTAGCCTAGACTGAGATGTAATA
>4.29|289009|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CGTGACAATGAATCTCCACTTCTTTGCCCCTATC
>4.30|289080|37|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GTTTAGATAATTTACATTAATCTTTGCACGAACTAAT
>4.31|289154|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TGATTCAACTCTTGAGAAAACATTTGTCTATCTA
>4.32|289225|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CTTCCTGAAAAAATGCAGGGAATAATCCACAGTT
>4.33|289296|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CCCCGAAAAAACCAAGCCCAGCAACTCTGATTGA
>4.34|289367|36|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTAAATTTACAGCACATCAACTAAGACATACTTTTG
>4.35|289440|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTATGCCTGGAAGGAAATCAGGAAAGATCCAGAT
>4.36|289511|37|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AATTGTCCTTTGGGACGATAAACTCTTAATGTTGCAA
>4.37|289585|36|NC_019678|CRISPRCasFinder,CRT
TTAATAGGAACTGCTGTTATTGGTGGAGTAACTACT
>4.38|289658|35|NC_019678|CRISPRCasFinder,CRT
CCTCCTTTTGTGTATATCTTTGCAATCTTCAGATT
>4.39|289730|34|NC_019678|CRISPRCasFinder,CRT
ATTGTTGCTAAATGTATTTATAAAATCAACAGAA
>4.40|289801|35|NC_019678|CRISPRCasFinder,CRT
TTATAGTAAAAATAATTGTAGATGGAGTACCAAAA
>4.41|289873|35|NC_019678|CRISPRCasFinder,CRT
ATGGTAAAGTGTATGTCCAATGGGATAGGATACTT
>4.42|289945|35|NC_019678|CRISPRCasFinder,CRT
AATGCTTTGCGAAATGCTAAACATTAACTTATATG
>4.43|290017|35|NC_019678|CRISPRCasFinder,CRT
TAAAAGATTAATATTACAATCTTCAAAAATTGATA
>4.44|290089|34|NC_019678|CRISPRCasFinder,CRT
TTTGTGACAGCCCTACCGATATGACCTTATACAA
>4.45|290160|34|NC_019678|CRISPRCasFinder,CRT
CTTATGCTCCTGAAGGCGTGTTGTTTGTGGATGA
>4.46|290231|35|NC_019678|CRISPRCasFinder,CRT
ATCAAAAAGATACGGGAACTTACAGAAAACAAATC
>4.47|290303|34|NC_019678|CRISPRCasFinder,CRT
GCTAGCCTCAGCGTAAAACACCTTAATATCCTCG
>4.48|290374|36|NC_019678|CRISPRCasFinder,CRT
AAAATAATTAAGAAACAAAAATAATCCATAAAAAAT
>4.49|290447|33|NC_019678|CRISPRCasFinder,CRT
CTACAAGCCAATGCCCATGAGATTCTTCAAAGA
>4.50|290517|34|NC_019678|CRISPRCasFinder,CRT
TAAGCAAATTCTAAAAGATAAATTTGATTTTTAT
>4.51|290588|35|NC_019678|CRISPRCasFinder,CRT
AATACTAAGTTTGCTATGGCATCTTGCCTTATCAG
>4.52|290660|35|NC_019678|CRISPRCasFinder,CRT
TCTGTAAGGACAGATTTATTACCTTTGCAAGATAA
>4.53|290732|41|NC_019678|CRISPRCasFinder,CRT
ATAATAAGCGCCACCTTCGTATACCTGCCCTTTTTGGGAGA
>4.54|290810|34|NC_019678|CRISPRCasFinder,CRT
TATCAAAAATATTTCATTTGAAGAACCTTTCAAA
>4.55|290881|34|NC_019678|CRISPRCasFinder,CRT
GAATAGATTCAACATATAATCCATCCAAAACTTT
>4.56|290952|36|NC_019678|CRISPRCasFinder,CRT
AGATAAGTCTTTTCGATAACATTTTTTCTTACTAAA
>4.57|289729|35|NC_019678|PILER-CR
CATTGTTGCTAAATGTATTTATAAAATCAACAGAA
>4.58|289800|36|NC_019678|PILER-CR
CTTATAGTAAAAATAATTGTAGATGGAGTACCAAAA
>4.59|289872|36|NC_019678|PILER-CR
TATGGTAAAGTGTATGTCCAATGGGATAGGATACTT
>4.60|289944|36|NC_019678|PILER-CR
CAATGCTTTGCGAAATGCTAAACATTAACTTATATG
>4.61|290016|36|NC_019678|PILER-CR
CTAAAAGATTAATATTACAATCTTCAAAAATTGATA
>4.62|290088|35|NC_019678|PILER-CR
CTTTGTGACAGCCCTACCGATATGACCTTATACAA
>4.63|290159|35|NC_019678|PILER-CR
CCTTATGCTCCTGAAGGCGTGTTGTTTGTGGATGA
>4.64|290230|36|NC_019678|PILER-CR
CATCAAAAAGATACGGGAACTTACAGAAAACAAATC
>4.65|290302|35|NC_019678|PILER-CR
CGCTAGCCTCAGCGTAAAACACCTTAATATCCTCG
>4.66|290373|37|NC_019678|PILER-CR
CAAAATAATTAAGAAACAAAAATAATCCATAAAAAAT
>4.67|290446|34|NC_019678|PILER-CR
CCTACAAGCCAATGCCCATGAGATTCTTCAAAGA
>4.68|290516|35|NC_019678|PILER-CR
CTAAGCAAATTCTAAAAGATAAATTTGATTTTTAT
>4.69|290587|36|NC_019678|PILER-CR
CAATACTAAGTTTGCTATGGCATCTTGCCTTATCAG
>4.70|290659|36|NC_019678|PILER-CR
CTCTGTAAGGACAGATTTATTACCTTTGCAAGATAA
>4.71|290731|42|NC_019678|PILER-CR
CATAATAAGCGCCACCTTCGTATACCTGCCCTTTTTGGGAGA
>4.72|290809|35|NC_019678|PILER-CR
CTATCAAAAATATTTCATTTGAAGAACCTTTCAAA
>4.73|290880|35|NC_019678|PILER-CR
CGAATAGATTCAACATATAATCCATCCAAAACTTT
>4.74|290951|37|NC_019678|PILER-CR
CAGATAAGTCTTTTCGATAACATTTTTTCTTACTAAA

CRISPR arrays and Neighbor proteins around NC_019678_4

CRISPR arrays

The CRISPR arrays of NC_019678_4

>merge|NC_019678|4|286960-291024|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTGGGAGAAAGTAAGAAAGCACGGTAAAGCGACCCGCGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTTGCTACCTGCATCTTTATTATCGGGCTTTATGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACCTAGATAGGTAGTACCTACTGCTAAAGCTTGCCAAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTTATTAATCTGAATAACCTTCCTTGAAGTGTTGAGGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTTATCTGGACCTTTTTGCCTGGAATACTCATACTCAAAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTGAGTATATCTGACTCAAAAAGGGCAGATTCAAGAAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACAAAAAAAGACTATAAATCCTCAAATAAGTTGAGTTGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTTATATCTACAACTTTTTTCTTCTCTTTCTATGAAAATGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTTAACAACTCTAAATACATCATACATTGTCTCAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACAAATATATGAATCACAACAAACACAAAAAAGGAAAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACATCCTATTGATTTACATGTAAATAATGATAGGAAAAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACCTCTAACAGATCTTTTTCGTAAATATTCCAATGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACAGATTCCATCCCCGCTTCGATAGCGCTCCAGTTTGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACAATCATGGATTAAATTATTTAATTGGCGCATACAAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACAAAATAAAAATATGAAAAAGAACAAGAAAAATCAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACGCAAAATATATTTCTGGAAGATTTGCTTCGGAAATTGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTTAGCAGATAAAAATAGTACACAAGCAGAAAAAAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACCAAGCTTTTTACCGTTTGTAACACCACTAGAACCGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTGAGAAACACGATGCATTCTGCTTGAATAAAAAGAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACATCCGCCAGTAATTTTACATTTATCTGCCAGTGATGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACAAAGAATTTAGCACTACGGCTGCACCTGCTGAATGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTACTTTACCTTTCTTTAAAAGCCATTCCCACATCAATGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACCTGGAAAATACTAGAATCATAGGCTTCAAACAAATTGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACCTCAATCTTGAAATCTTCTAAGCCTGAGCCTATGAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACCAACATCTAAGGAATCCGTACAGCTTTGACTACGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTTGAAGCCTTATAGAAGCTTTTAATTGCAAGTTTGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACCTATTGAGATTAATGAAACTTGGGAAAATAACCTGTTGAAATCAACTTCAATCCCTATCAGGGATTGAAACAAATTGCATATTTTAGCCTAGACTGAGATGTAATAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACCGTGACAATGAATCTCCACTTCTTTGCCCCTATCGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACGTTTAGATAATTTACATTAATCTTTGCACGAACTAATGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTGATTCAACTCTTGAGAAAACATTTGTCTATCTAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACCTTCCTGAAAAAATGCAGGGAATAATCCACAGTTGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACCCCCGAAAAAACCAAGCCCAGCAACTCTGATTGAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTTAAATTTACAGCACATCAACTAAGACATACTTTTGGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTTATGCCTGGAAGGAAATCAGGAAAGATCCAGATGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACAATTGTCCTTTGGGACGATAAACTCTTAATGTTGCAAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTTAATAGGAACTGCTGTTATTGGTGGAGTAACTACTGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACCCTCCTTTTGTGTATATCTTTGCAATCTTCAGATTGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACATTGTTGCTAAATGTATTTATAAAATCAACAGAAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTTATAGTAAAAATAATTGTAGATGGAGTACCAAAAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAATATGGTAAAGTGTATGTCCAATGGGATAGGATACTTGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACAATGCTTTGCGAAATGCTAAACATTAACTTATATGGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTAAAAGATTAATATTACAATCTTCAAAAATTGATAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTTTGTGACAGCCCTACCGATATGACCTTATACAAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACCTTATGCTCCTGAAGGCGTGTTGTTTGTGGATGAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACATCAAAAAGATACGGGAACTTACAGAAAACAAATCGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACGCTAGCCTCAGCGTAAAACACCTTAATATCCTCGGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACAAAATAATTAAGAAACAAAAATAATCCATAAAAAATGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACCTACAAGCCAATGCCCATGAGATTCTTCAAAGAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTAAGCAAATTCTAAAAGATAAATTTGATTTTTATGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACAATACTAAGTTTGCTATGGCATCTTGCCTTATCAGGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTCTGTAAGGACAGATTTATTACCTTTGCAAGATAAGTTGAAATCAACTTAAATCCCTATCAGGGATTAAAACATAATAAGCGCCACCTTCGTATACCTGCCCTTTTTGGGAGAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTATCAAAAATATTTCATTTGAAGAACCTTTCAAAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACGAATAGATTCAACATATAATCCATCCAAAACTTTGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACAGATAAGTCTTTTCGATAACATTTTTTCTTACTAAAGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAT

>NC_019678|4|2|286960-289584|PILER-CR
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TGGGAGAAAGTAAGAAAGCACGGTAAAGCGACCCGC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTGCTACCTGCATCTTTATTATCGGGCTTTAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTAGATAGGTAGTACCTACTGCTAAAGCTTGCCAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATTAATCTGAATAACCTTCCTTGAAGTGTTGAG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATCTGGACCTTTTTGCCTGGAATACTCATACTCAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TGAGTATATCTGACTCAAAAAGGGCAGATTCAAGAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAAAAAAGACTATAAATCCTCAAATAAGTTGAGTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATATCTACAACTTTTTTCTTCTCTTTCTATGAAAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTAACAACTCTAAATACATCATACATTGTCTCA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAATATATGAATCACAACAAACACAAAAAAGGAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	ATCCTATTGATTTACATGTAAATAATGATAGGAAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTCTAACAGATCTTTTTCGTAAATATTCCAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AGATTCCATCCCCGCTTCGATAGCGCTCCAGTTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AATCATGGATTAAATTATTTAATTGGCGCATACAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAAATAAAAATATGAAAAAGAACAAGAAAAATCA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	GCAAAATATATTTCTGGAAGATTTGCTTCGGAAATT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTAGCAGATAAAAATAGTACACAAGCAGAAAAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CAAGCTTTTTACCGTTTGTAACACCACTAGAACC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TGAGAAACACGATGCATTCTGCTTGAATAAAAAGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	ATCCGCCAGTAATTTTACATTTATCTGCCAGTGAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAAGAATTTAGCACTACGGCTGCACCTGCTGAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TACTTTACCTTTCTTTAAAAGCCATTCCCACATCAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTGGAAAATACTAGAATCATAGGCTTCAAACAAATT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTCAATCTTGAAATCTTCTAAGCCTGAGCCTATGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CAACATCTAAGGAATCCGTACAGCTTTGACTAC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTGAAGCCTTATAGAAGCTTTTAATTGCAAGTTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTATTGAGATTAATGAAACTTGGGAAAATAACCT
GTTGAAATCAACTTCAATCCCTATCAGGGATTGAAAC	AAATTGCATATTTTAGCCTAGACTGAGATGTAATA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CGTGACAATGAATCTCCACTTCTTTGCCCCTATC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	GTTTAGATAATTTACATTAATCTTTGCACGAACTAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TGATTCAACTCTTGAGAAAACATTTGTCTATCTA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTTCCTGAAAAAATGCAGGGAATAATCCACAGTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CCCCGAAAAAACCAAGCCCAGCAACTCTGATTGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTAAATTTACAGCACATCAACTAAGACATACTTTTG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATGCCTGGAAGGAAATCAGGAAAGATCCAGAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AATTGTCCTTTGGGACGATAAACTCTTAATGTTGCAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTTAATAGGAACTGCTGTTATTGGTGGAGTAACTACTGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACCCTCCTTTTGTGTATATCTTTGCAATCTTCAGATTGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CATTGTTGCTAAATGTATTTATAAAATCAACAGAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CTTATAGTAAAAATAATTGTAGATGGAGTACCAAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	TATGGTAAAGTGTATGTCCAATGGGATAGGATACTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CAATGCTTTGCGAAATGCTAAACATTAACTTATATG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CTAAAAGATTAATATTACAATCTTCAAAAATTGATA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CTTTGTGACAGCCCTACCGATATGACCTTATACAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CCTTATGCTCCTGAAGGCGTGTTGTTTGTGGATGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CATCAAAAAGATACGGGAACTTACAGAAAACAAATC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CGCTAGCCTCAGCGTAAAACACCTTAATATCCTCG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CAAAATAATTAAGAAACAAAAATAATCCATAAAAAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CCTACAAGCCAATGCCCATGAGATTCTTCAAAGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CTAAGCAAATTCTAAAAGATAAATTTGATTTTTAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CAATACTAAGTTTGCTATGGCATCTTGCCTTATCAG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CTCTGTAAGGACAGATTTATTACCTTTGCAAGATAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTAAAA	CATAATAAGCGCCACCTTCGTATACCTGCCCTTTTTGGGAGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CTATCAAAAATATTTCATTTGAAGAACCTTTCAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CGAATAGATTCAACATATAATCCATCCAAAACTTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CAGATAAGTCTTTTCGATAACATTTTTTCTTACTAAA


>NC_019678|4|4|286960-291024|CRISPRCasFinder
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TGGGAGAAAGTAAGAAAGCACGGTAAAGCGACCCGC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTGCTACCTGCATCTTTATTATCGGGCTTTAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTAGATAGGTAGTACCTACTGCTAAAGCTTGCCAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATTAATCTGAATAACCTTCCTTGAAGTGTTGAG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATCTGGACCTTTTTGCCTGGAATACTCATACTCAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TGAGTATATCTGACTCAAAAAGGGCAGATTCAAGAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAAAAAAGACTATAAATCCTCAAATAAGTTGAGTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATATCTACAACTTTTTTCTTCTCTTTCTATGAAAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTAACAACTCTAAATACATCATACATTGTCTCA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAATATATGAATCACAACAAACACAAAAAAGGAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	ATCCTATTGATTTACATGTAAATAATGATAGGAAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTCTAACAGATCTTTTTCGTAAATATTCCAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AGATTCCATCCCCGCTTCGATAGCGCTCCAGTTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AATCATGGATTAAATTATTTAATTGGCGCATACAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAAATAAAAATATGAAAAAGAACAAGAAAAATCA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	GCAAAATATATTTCTGGAAGATTTGCTTCGGAAATT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTAGCAGATAAAAATAGTACACAAGCAGAAAAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CAAGCTTTTTACCGTTTGTAACACCACTAGAACC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TGAGAAACACGATGCATTCTGCTTGAATAAAAAGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	ATCCGCCAGTAATTTTACATTTATCTGCCAGTGAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAAGAATTTAGCACTACGGCTGCACCTGCTGAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TACTTTACCTTTCTTTAAAAGCCATTCCCACATCAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTGGAAAATACTAGAATCATAGGCTTCAAACAAATT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTCAATCTTGAAATCTTCTAAGCCTGAGCCTATGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CAACATCTAAGGAATCCGTACAGCTTTGACTAC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTGAAGCCTTATAGAAGCTTTTAATTGCAAGTTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTATTGAGATTAATGAAACTTGGGAAAATAACCT
GTTGAAATCAACTTCAATCCCTATCAGGGATTGAAAC	AAATTGCATATTTTAGCCTAGACTGAGATGTAATA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CGTGACAATGAATCTCCACTTCTTTGCCCCTATC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	GTTTAGATAATTTACATTAATCTTTGCACGAACTAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TGATTCAACTCTTGAGAAAACATTTGTCTATCTA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTTCCTGAAAAAATGCAGGGAATAATCCACAGTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CCCCGAAAAAACCAAGCCCAGCAACTCTGATTGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTAAATTTACAGCACATCAACTAAGACATACTTTTG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATGCCTGGAAGGAAATCAGGAAAGATCCAGAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AATTGTCCTTTGGGACGATAAACTCTTAATGTTGCAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTAATAGGAACTGCTGTTATTGGTGGAGTAACTACT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CCTCCTTTTGTGTATATCTTTGCAATCTTCAGATT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	ATTGTTGCTAAATGTATTTATAAAATCAACAGAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATAGTAAAAATAATTGTAGATGGAGTACCAAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAT	ATGGTAAAGTGTATGTCCAATGGGATAGGATACTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AATGCTTTGCGAAATGCTAAACATTAACTTATATG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TAAAAGATTAATATTACAATCTTCAAAAATTGATA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTTGTGACAGCCCTACCGATATGACCTTATACAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTTATGCTCCTGAAGGCGTGTTGTTTGTGGATGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	ATCAAAAAGATACGGGAACTTACAGAAAACAAATC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	GCTAGCCTCAGCGTAAAACACCTTAATATCCTCG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAAATAATTAAGAAACAAAAATAATCCATAAAAAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTACAAGCCAATGCCCATGAGATTCTTCAAAGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TAAGCAAATTCTAAAAGATAAATTTGATTTTTAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AATACTAAGTTTGCTATGGCATCTTGCCTTATCAG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TCTGTAAGGACAGATTTATTACCTTTGCAAGATAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTAAAAC	ATAATAAGCGCCACCTTCGTATACCTGCCCTTTTTGGGAGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TATCAAAAATATTTCATTTGAAGAACCTTTCAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	GAATAGATTCAACATATAATCCATCCAAAACTTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AGATAAGTCTTTTCGATAACATTTTTTCTTACTAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAT

>NC_019678|4|2|286960-291024|CRT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TGGGAGAAAGTAAGAAAGCACGGTAAAGCGACCCGC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTGCTACCTGCATCTTTATTATCGGGCTTTAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTAGATAGGTAGTACCTACTGCTAAAGCTTGCCAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATTAATCTGAATAACCTTCCTTGAAGTGTTGAG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATCTGGACCTTTTTGCCTGGAATACTCATACTCAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TGAGTATATCTGACTCAAAAAGGGCAGATTCAAGAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAAAAAAGACTATAAATCCTCAAATAAGTTGAGTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATATCTACAACTTTTTTCTTCTCTTTCTATGAAAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTAACAACTCTAAATACATCATACATTGTCTCA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAATATATGAATCACAACAAACACAAAAAAGGAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	ATCCTATTGATTTACATGTAAATAATGATAGGAAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTCTAACAGATCTTTTTCGTAAATATTCCAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AGATTCCATCCCCGCTTCGATAGCGCTCCAGTTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AATCATGGATTAAATTATTTAATTGGCGCATACAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAAATAAAAATATGAAAAAGAACAAGAAAAATCA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	GCAAAATATATTTCTGGAAGATTTGCTTCGGAAATT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTAGCAGATAAAAATAGTACACAAGCAGAAAAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CAAGCTTTTTACCGTTTGTAACACCACTAGAACC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TGAGAAACACGATGCATTCTGCTTGAATAAAAAGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	ATCCGCCAGTAATTTTACATTTATCTGCCAGTGAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAAGAATTTAGCACTACGGCTGCACCTGCTGAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TACTTTACCTTTCTTTAAAAGCCATTCCCACATCAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTGGAAAATACTAGAATCATAGGCTTCAAACAAATT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTCAATCTTGAAATCTTCTAAGCCTGAGCCTATGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CAACATCTAAGGAATCCGTACAGCTTTGACTAC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTGAAGCCTTATAGAAGCTTTTAATTGCAAGTTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTATTGAGATTAATGAAACTTGGGAAAATAACCT
GTTGAAATCAACTTCAATCCCTATCAGGGATTGAAAC	AAATTGCATATTTTAGCCTAGACTGAGATGTAATA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CGTGACAATGAATCTCCACTTCTTTGCCCCTATC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	GTTTAGATAATTTACATTAATCTTTGCACGAACTAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TGATTCAACTCTTGAGAAAACATTTGTCTATCTA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTTCCTGAAAAAATGCAGGGAATAATCCACAGTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CCCCGAAAAAACCAAGCCCAGCAACTCTGATTGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTAAATTTACAGCACATCAACTAAGACATACTTTTG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATGCCTGGAAGGAAATCAGGAAAGATCCAGAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AATTGTCCTTTGGGACGATAAACTCTTAATGTTGCAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTAATAGGAACTGCTGTTATTGGTGGAGTAACTACT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CCTCCTTTTGTGTATATCTTTGCAATCTTCAGATT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	ATTGTTGCTAAATGTATTTATAAAATCAACAGAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATAGTAAAAATAATTGTAGATGGAGTACCAAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAT	ATGGTAAAGTGTATGTCCAATGGGATAGGATACTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AATGCTTTGCGAAATGCTAAACATTAACTTATATG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TAAAAGATTAATATTACAATCTTCAAAAATTGATA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTTGTGACAGCCCTACCGATATGACCTTATACAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTTATGCTCCTGAAGGCGTGTTGTTTGTGGATGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	ATCAAAAAGATACGGGAACTTACAGAAAACAAATC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	GCTAGCCTCAGCGTAAAACACCTTAATATCCTCG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAAATAATTAAGAAACAAAAATAATCCATAAAAAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTACAAGCCAATGCCCATGAGATTCTTCAAAGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TAAGCAAATTCTAAAAGATAAATTTGATTTTTAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AATACTAAGTTTGCTATGGCATCTTGCCTTATCAG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TCTGTAAGGACAGATTTATTACCTTTGCAAGATAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTAAAAC	ATAATAAGCGCCACCTTCGTATACCTGCCCTTTTTGGGAGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TATCAAAAATATTTCATTTGAAGAACCTTTCAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	GAATAGATTCAACATATAATCCATCCAAAACTTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AGATAAGTCTTTTCGATAACATTTTTTCTTACTAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAT

>NC_019678|4|3|289693-291023|PILER-CR
	TGGGAGAAAGTAAGAAAGCACGGTAAAGCGACCCGC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTGCTACCTGCATCTTTATTATCGGGCTTTAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTAGATAGGTAGTACCTACTGCTAAAGCTTGCCAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATTAATCTGAATAACCTTCCTTGAAGTGTTGAG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATCTGGACCTTTTTGCCTGGAATACTCATACTCAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TGAGTATATCTGACTCAAAAAGGGCAGATTCAAGAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAAAAAAGACTATAAATCCTCAAATAAGTTGAGTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATATCTACAACTTTTTTCTTCTCTTTCTATGAAAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTAACAACTCTAAATACATCATACATTGTCTCA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAATATATGAATCACAACAAACACAAAAAAGGAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	ATCCTATTGATTTACATGTAAATAATGATAGGAAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTCTAACAGATCTTTTTCGTAAATATTCCAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AGATTCCATCCCCGCTTCGATAGCGCTCCAGTTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AATCATGGATTAAATTATTTAATTGGCGCATACAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAAATAAAAATATGAAAAAGAACAAGAAAAATCA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	GCAAAATATATTTCTGGAAGATTTGCTTCGGAAATT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTAGCAGATAAAAATAGTACACAAGCAGAAAAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CAAGCTTTTTACCGTTTGTAACACCACTAGAACC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TGAGAAACACGATGCATTCTGCTTGAATAAAAAGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	ATCCGCCAGTAATTTTACATTTATCTGCCAGTGAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AAAGAATTTAGCACTACGGCTGCACCTGCTGAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TACTTTACCTTTCTTTAAAAGCCATTCCCACATCAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTGGAAAATACTAGAATCATAGGCTTCAAACAAATT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTCAATCTTGAAATCTTCTAAGCCTGAGCCTATGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CAACATCTAAGGAATCCGTACAGCTTTGACTAC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTGAAGCCTTATAGAAGCTTTTAATTGCAAGTTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTATTGAGATTAATGAAACTTGGGAAAATAACCT
GTTGAAATCAACTTCAATCCCTATCAGGGATTGAAAC	AAATTGCATATTTTAGCCTAGACTGAGATGTAATA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CGTGACAATGAATCTCCACTTCTTTGCCCCTATC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	GTTTAGATAATTTACATTAATCTTTGCACGAACTAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TGATTCAACTCTTGAGAAAACATTTGTCTATCTA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CTTCCTGAAAAAATGCAGGGAATAATCCACAGTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	CCCCGAAAAAACCAAGCCCAGCAACTCTGATTGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTAAATTTACAGCACATCAACTAAGACATACTTTTG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	TTATGCCTGGAAGGAAATCAGGAAAGATCCAGAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAAC	AATTGTCCTTTGGGACGATAAACTCTTAATGTTGCAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACTTAATAGGAACTGCTGTTATTGGTGGAGTAACTACTGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAACCCTCCTTTTGTGTATATCTTTGCAATCTTCAGATTGTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CATTGTTGCTAAATGTATTTATAAAATCAACAGAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CTTATAGTAAAAATAATTGTAGATGGAGTACCAAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	TATGGTAAAGTGTATGTCCAATGGGATAGGATACTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CAATGCTTTGCGAAATGCTAAACATTAACTTATATG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CTAAAAGATTAATATTACAATCTTCAAAAATTGATA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CTTTGTGACAGCCCTACCGATATGACCTTATACAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CCTTATGCTCCTGAAGGCGTGTTGTTTGTGGATGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CATCAAAAAGATACGGGAACTTACAGAAAACAAATC
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CGCTAGCCTCAGCGTAAAACACCTTAATATCCTCG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CAAAATAATTAAGAAACAAAAATAATCCATAAAAAAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CCTACAAGCCAATGCCCATGAGATTCTTCAAAGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CTAAGCAAATTCTAAAAGATAAATTTGATTTTTAT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CAATACTAAGTTTGCTATGGCATCTTGCCTTATCAG
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CTCTGTAAGGACAGATTTATTACCTTTGCAAGATAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTAAAA	CATAATAAGCGCCACCTTCGTATACCTGCCCTTTTTGGGAGA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CTATCAAAAATATTTCATTTGAAGAACCTTTCAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CGAATAGATTCAACATATAATCCATCCAAAACTTT
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA	CAGATAAGTCTTTTCGATAACATTTTTTCTTACTAAA
GTTGAAATCAACTTAAATCCCTATCAGGGATTGAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015116411.1|276942_280356_+|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	cas10d	cd09712_cas10d_CAS-I-D	gnl|CDD|274469
NC_019678.1|WP_015116426.1|300963_302031_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340832
NC_019678.1|WP_015116409.1|273164_274037_-|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl|CDD|379100
NC_019678.1|WP_015116415.1|283597_284191_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|187768
NC_019678.1|WP_015116410.1|274136_276314_+|type-I-D-CRISPR-associated-helicase-Cas3'	cas3	cd09710_cas3_CAS-I-D	gnl|CDD|187841
NC_019678.1|WP_083894029.1|284290_285088_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NC_019678.1|WP_015116412.1|280506_281550_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	gnl|CDD|375747
NC_019678.1|WP_015116416.1|286459_286732_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NC_019678.1|WP_015116421.1|296918_297638_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_019678.1|WP_015116420.1|294186_295470_-|response-regulator	unknown	unknown	gnl|CDD|274362
NC_019678.1|WP_015116414.1|282517_283360_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl|CDD|227838
NC_019678.1|WP_015116423.1|298428_299022_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_044290703.1|272228_273098_+|fructosamine-kinase-family-protein	unknown	unknown	gnl|CDD|367711
NC_019678.1|WP_015116427.1|302869_305056_-|polysaccharide-biosynthesis-tyrosine-autokinase	unknown	unknown	gnl|CDD|349772
NC_019678.1|WP_015116419.1|292963_294088_-|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl|CDD|223715
NC_019678.1|WP_015116413.1|281552_282284_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	gnl|CDD|187842
NC_019678.1|WP_015116424.1|299484_300513_-|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl|CDD|176197
NC_019678.1|WP_015116422.1|297836_298187_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015116418.1|292224_292686_+|response-regulator	unknown	unknown	gnl|CDD|381100
NC_019678.1|WP_015116417.1|291146_291347_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019678.1|WP_015116411.1|276942_280356_+|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	cas10d	cd09712_cas10d_CAS-I-D	2.5e-304	1006.4	1.8
NC_019678.1|WP_015116409.1|273164_274037_-|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	6e-15	50.4	1.4
NC_019678.1|WP_015116410.1|274136_276314_+|type-I-D-CRISPR-associated-helicase-Cas3'	cas3	cd09710_cas3_CAS-I-D	8.4e-124	407.8	0.0
NC_019678.1|WP_015116415.1|283597_284191_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	2.9e-51	168.9	2.3
NC_019678.1|WP_083894029.1|284290_285088_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	1.2e-86	285.4	0.0
NC_019678.1|WP_015116412.1|280506_281550_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	5.8e-110	361.7	0.0
NC_019678.1|WP_015116413.1|281552_282284_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	2.6e-76	250.6	2.4
NC_019678.1|WP_015116416.1|286459_286732_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	8e-33	107.3	0.4
NC_019678.1|WP_015116414.1|282517_283360_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	3.5e-68	224.7	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015116411.1|276942_280356_+|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	gnl|CDD|274469	TIGR03174, cas_Csc3, CRISPR type I-D/CYANO-associated protein Csc3/Cas10d. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family is a CRISPR-associated (Cas) family strictly associated with the Cyano subtype of CRISPR/Cas locus, found in several species of Cyanobacteria and several archaeal species. This family is designated Csc3 for CRISPR/Cas Subtype Cyano protein 3, as it is often the third gene upstream of the core cas genes, cas3-cas4-cas1-cas2.	0
NC_019678.1|WP_015116426.1|300963_302031_-|glycosyltransferase-family-4-protein	gnl|CDD|340832	cd03802, GT4_AviGT4-like, UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.	4.58238e-156
NC_019678.1|WP_015116409.1|273164_274037_-|WYL-domain-containing-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	2.23702e-07
NC_019678.1|WP_015116415.1|283597_284191_+|CRISPR-associated-protein-Cas4	gnl|CDD|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	2.5553e-56
NC_019678.1|WP_015116410.1|274136_276314_+|type-I-D-CRISPR-associated-helicase-Cas3'	gnl|CDD|187841	cd09710, Cas3_I-D, CRISPR/Cas system-associated protein Cas3; Distinct diverged subfamily of Cas3 helicase domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Diverged DNA helicase Cas3'; signature gene for Type I and subtype I-D.	7.75119e-137
NC_019678.1|WP_083894029.1|284290_285088_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	2.01111e-114
NC_019678.1|WP_015116412.1|280506_281550_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2	gnl|CDD|375747	pfam18320, Csc2, Csc2 Crispr. The Csc2 Crispr family of proteins forms a core RNA recognition motif-like domain, flanked by three peripheral insertion domains: a lid domain, a Zinc-binding domain and a helical domain. The CRISPR-Cas system is possibly a mechanism of defence against invading pathogens and plasmids that functions analogously to the RNA interference (RNAi) systems in eukaryotes.	8.18923e-173
NC_019678.1|WP_015116416.1|286459_286732_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.06857e-36
NC_019678.1|WP_015116421.1|296918_297638_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.88974e-70
NC_019678.1|WP_015116420.1|294186_295470_-|response-regulator	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	5.30973e-57
NC_019678.1|WP_015116414.1|282517_283360_+|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	9.77235e-54
NC_019678.1|WP_044290703.1|272228_273098_+|fructosamine-kinase-family-protein	gnl|CDD|367711	pfam03881, Fructosamin_kin, Fructosamine kinase. This family includes eukaryotic fructosamine-3-kinase enzymes. The family also includes bacterial members that have not been characterized but probably have a similar or identical function.	7.12701e-161
NC_019678.1|WP_015116427.1|302869_305056_-|polysaccharide-biosynthesis-tyrosine-autokinase	gnl|CDD|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	2.25571e-67
NC_019678.1|WP_015116419.1|292963_294088_-|hybrid-sensor-histidine-kinase/response-regulator	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.05137e-49
NC_019678.1|WP_015116413.1|281552_282284_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1	gnl|CDD|187842	cd09711, Csc1_I-D, CRISPR/Cas system-associated protein Csc1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas5 ortholog; also known as CasA/Cse1 family.	1.57713e-78
NC_019678.1|WP_015116424.1|299484_300513_-|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl|CDD|176197	cd08235, iditol_2_DH_like, L-iditol 2-dehydrogenase. Putative L-iditol 2-dehydrogenase based on annotation of some members in this subgroup. L-iditol 2-dehydrogenase catalyzes the NAD+-dependent conversion of L-iditol to L-sorbose in fructose and mannose metabolism. This enzyme is related to sorbitol dehydrogenase, alcohol dehydrogenase, and other medium chain dehydrogenase/reductases. The zinc-dependent alcohol dehydrogenase (ADH-Zn)-like family of proteins is a diverse group of proteins related to the first identified member, class I mammalian ADH. This group is also called the medium chain dehydrogenases/reductase family (MDR) to highlight its broad range of activities and to distinguish from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal GroES-like catalytic domain. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.53228e-120
NC_019678.1|WP_015116418.1|292224_292686_+|response-regulator	gnl|CDD|381100	cd17548, REC_DivK-like, phosphoacceptor receiver (REC) domain of DivK and similar proteins. Caulobacter crescentus DivK is an essential response regulator that is involved in the complex phosphorelay pathways controlling both cell division and motility. It localizes cell cycle regulators to specific poles of the cell during division. DivK contains a stand-alone REC domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.58657e-31

Protein sequences

>NC_019678.1|WP_015116416.1|286459_286732_+|CRISPR-associated-endonuclease-Cas2
MNVVVSYDISEDKRRTKIHKVLKSYGQWVQYSIFECQLTDTQYARLRSRLNKLIKSDTDSIRFYFLCACCFGKVERIGGEQPRDDSIFFA
>NC_019678.1|WP_083894029.1|284290_285088_+|CRISPR-associated-endonuclease-Cas1
MGTVYITQMDSFVGKVDERLTVKFEKNKILDVPLIKVDGVVVLGRATISPAVVYELLERHIPLTFLTETGRYLGRLEPEVTKNLFLRKAQWRATENSPTSVGAVQSFVRGKLKNYRNVMVRRQRESAKLDLSKNITHLENAIAPIDTTENIDSLRGLEGAGSAAYFSSFDQMIRTTEFKFTRRVRRPPTDPVNSLLSFGYSLLRHDVQGAVNIVGFDPYLGYLHCDRYGRPSLALDLMEEFRPLVVDAMVLSTLNKYLCKINCIF
>NC_019678.1|WP_015116415.1|283597_284191_+|CRISPR-associated-protein-Cas4
MNNTDYITIASLNQYSYCPHRCWRMFCLGEFTDNQYTIEGTSLHERVHTVSENNQEETWQIRAIWLKSEKYKLIGKSDLIELENDEWYPVEYKRGKKGEWDNDELQVCAQALCLEEMTGKDITTGYIYYAQNNKRQLVEINDDLREETIATIANVTQLLETGKMPPAIYSKRCKGCSLYSQCLPMAVDKVKRYQEAQ
>NC_019678.1|WP_015116414.1|282517_283360_+|CRISPR-associated-endoribonuclease-Cas6
MPHSLILNLTPKSPIYPQFLTGRHLHALFLTLVSSVDKELGTHLHDSKADKAFTLSPLQISKRNSPIAKGSKRGSILKSQHQEAISTGTPCWWRISLLDDALFGKLTQLWLNLNPQQPWHLGSADLYITSIQGTPQSTQPWANACSYNQLYEQASDSERIISVNFATPTAWRQGKYDSTLPTRESVFKSLLSRWNKYSGIEFENLNFDAIFPSFINIHTEIVPDSRSKFIGIVGEVSYRIMGDVEAIQIKQINALADFALYCGIGRKTTMGMGMGRRVRS
>NC_019678.1|WP_015116413.1|281552_282284_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1
MTIIYCCQLELHDSVYFATREIGRLYETEPVIHNYALCYALGLVDSEIYATTVSEEHSYRYFCPEQVPKYEEHLTPLNQQGIYVTPAHSIHHTSVLNTWKYANNNYHVEMQKTQKNIPSFGRAKEIAPESQFEFFIISKNDIELKGKLPKWIRLGKWMSKAEVEIQQVAKLESKTGDFTFPYPLNPLDVMFTNQVISYDVVNMPPVSLIQNVTITKGEFFQFENPFTSQKLKLPAKMAYRFKG
>NC_019678.1|WP_015116412.1|280506_281550_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2
MTFLKSIDSKLFHTEIPYKPMGKYVHFLTIRVTESYPLFQTDGELNKSRVRAGKKDKNTISRLSMFKRKQSTPERLVGRELMRNYGLVKDEECEYNVKFAMDNPDCIIYGFAIGDSGSEKSKVVVDTAFSITPFDESHETFTLNAPFENGTMTSKGENGSKPGEVTSRINQQDHIRPQVFFPSIVTLKDPTEASFLYVLNNILRTRHYGAQTTRTGRVRNELIGVIFADGEITSNLRWTQAIYDEMKANNSINSPEPLDEDDVITAAKTAIESQMAEEFIVHQDYLNDEFAALLKEVKAITANEDELKKLLKKADVEAKEYAKVHIKVKSKDKDKNKDKNKETAANS
>NC_019678.1|WP_015116411.1|276942_280356_+|type-I-D-CRISPR-associated-protein-Cas10d/Csc3
MTKKINDLEEHKQLSLFDIEDNSQSEDSDYDWLDDEDVDFGFETSDRTVETAQELLTYKLLREAIEAQNPDDEVMADFAKYVLPNLLQIAIGVTAKGGKYFDKLDREKAAAGKAKVRRDNAADQSLNTHLLNGLFPANLIERRLVKLNTTVMRVVGEVERRLLVAGFILHDFEKFPDVPDDCRKLAIEEHRRIIDQKVRQLGLDKFINPSQSEAYQEYLDDLLCMAYNAQRRWDTNWNFSEFGLNPQLRDRTLRCLSELTCLADSLASIIKHPQDAQSYKFKELLSALSDGELQFTYHSIAENRGVLTNVVNNALIAAHTSLNTENNICYEPLLYLPTGVIYLASRDAPAISQEDLPDRVISTIKSLCASQLRLRQTGFGRDGKGMKYADYYNLFFDDVALMQVGLDATLRILHPKKDSVAKSRSDNLVKFQEKDVLPSDFDLKFSDDIRIDQIAEFGDLIARKIWGEKVKQIESLRKKDKKLPELPQLDLIHKVAEFWNLTEYLPEVKAIQRINESLKENKLKGNTGGVPYEWYYLAAKYLEHNPGIEDIREVCQPVITFVQSLIEPIVSQYQIADGWDDLRLWVQRVIMLPGSNREANENQVETFLDELSNYNTAKKSGRGKQLICSISHSAYTVTEQMESAVLFTPQVYTNKQMLGGSNAKRNISSIAGVEMMLRQILMNQTQAVGKRFEDGKYRYLYFYPTYYFTPETNKFLQIAYSGIAQTRFDTSIRNHFIPKNLQANLGKDKYQSVDSFLIDEDLQSQKNLPEDDPNYKKDRTFKLSYPEDQPLTFYFMALPPGRDSSDTESWIMPSWLAFAFPMILDVKTVVSESPIPPFNDGAEFEESVFLDSAPHAFRALVKQDKFRLDYILEGWQDNNKTYSAPLNVLTAAYAIHLDVNAKQGKSGYDANWGKFTELAKDFETSPLYVFSYLNRWVRKQGVETARIEKIKLYAYDFYPCFDAYVKYDNIQEKLIVESESSLCHTQKLTELYRRFYRANKKYNPKSNAVLKPIDIAAETILKAELSVHTGECLVLVVAAEVFKLMDRVHASTAEGRWVFNHKEREEERQAVLEFARYFVEDIFEKSFAGDRARLAGRQINLIRDTCEFLYRLENDKENQLQGNDSKKENDSETLISS
>NC_019678.1|WP_015116410.1|274136_276314_+|type-I-D-CRISPR-associated-helicase-Cas3'
MSNYRIQLKSIYSCPADEVPEDVNLPKGWMLAWHQLETLKALRNADIDVVINTAMTGDGKSLAAYLQVLQENCCAIGLYPTNELARDQETQTKGYIETFQPRNEPRVTRLSGADLEIYAENEGLKKSSAISTRTHQSEVVLTNPDIFHYLHRGAYLTPDDSPDKLWGRIDKDFDLFILDEFHVFAAPQIASVINTMLLIKFTNRRKKFLFLSATPDDNLIGKLQKAGFRCKVINPLEENKYRFPDTLAESLELKNKNWRQVSRPISLNFISLEPTFKASENWLRENSSLILEYFQNHPGSKGAIILNSIAAVKRLVPFFEELLQPSNLSVGENTGLSGRTQKEFSLSADLVLGTSTIDVGVDFKINFLIFESADAGNFIQRLGRLGRHDGYEKDGEDIKFDNFTAYALIPKFLVERLFKEDSPPLQENGIYNRPFFHNTIIEKYRQINDFSGYYRRWAGVQSVQLTWKLKHKTVKQQYSETVKEFSKTCESVFDTKLNSVFGCIKGWEKTWNELSGTKGNPIAEDAASFRGSSSLQCGIYDLTEQNEADRFKTYDLPGIVANLDIEMWTEAGFIRTLKDTASRINQPIPKGRFAHCLGFMKLRSYREERLNWKFIYSGDLQPIADAWKVQVLKGIEIWQPDNPWIGEINKRLKKKGLVCYVLRNPVTEIRMRLRLPMHFQIYPICDKYSINDATAPYSIAFSQSGLLLDTLAYTFKGKGDETWIY
>NC_019678.1|WP_015116409.1|273164_274037_-|WYL-domain-containing-protein
MSRKGKSITLSVSERDKAELETLALEFGCNWGERPNISKLVESIARRQLIVAPNNDWTNERIKALETARKALVDLGKTDEAKQIAELLKSRSELTLPFREEIETFLNHPLPAWRQQVDNLIHRQQPFRLSYQDAAERVWSYTVLHARIVPIEKRQYLLCRAEESEGNQDVEGLRHNWTLRLDRIQEAAVVSIDKPWENDLERIAVEFHLLSRLAFAYQRKTEDIFVSELEAEPPIKRVVRNISGTFWFFREITRYGKDCEIVSPEAVRSQFKQNLKSLCQAYDLEIKEED
>NC_019678.1|WP_044290703.1|272228_273098_+|fructosamine-kinase-family-protein
MWTEINAQISQATGENFQTQQRRSVSGGCINQGYSVSDGKRTFFVKLNQAFQVAMFEAEALGVKQMYDTNTIRVPKPICYGVAGNSCYIVLEWLEIGRGDSKASEEMGRKLAQMHKKSLSEKFGWDMNNTIGSTPQINTWTDDWVEFWTKHRLGYQFELGKRRGGSFPQASELLNAIPELLAGHEVQPSLVHGDLWGGNAGFTVDGEPIIFDPATYFGDREVDIAMTEVFGGFSTAFYQGYNEVFPLDHGYEKRKTLYNLYHILNHFNLFGGGYGSQANGMIGRILSNK
>NC_019678.1|WP_015116417.1|291146_291347_-|hypothetical-protein
MIHIRFEGRSYDVEQSKLGLEQNMSDTDIKQRLAQHFDVAVNSFQYYVIDRRPNGDLIIRPEAVYG
>NC_019678.1|WP_015116418.1|292224_292686_+|response-regulator
MNLANTFSMDKNHTCEPPLVLVVEDNEDNLFLISHILESLGCRVIFQRVGSEATVILAKEHHPDLILLDIVLPDVSGIDILQLLRQEPLTCDLPAIAVTALATEQNRENIIRAGFNNYIIKPYLIEELEEMIFPYICGKLNSSSKYVVGQDKL
>NC_019678.1|WP_015116419.1|292963_294088_-|hybrid-sensor-histidine-kinase/response-regulator
MSIQDSQVLDRILAVDDIPDNLFLVQALLESEGYEVKLVTDGGTAIKEVKKTPPSLILLDVMMPEIDGYEVTRRIRSITDDNYIPILLVTAFDDVSVVEGLDAGADDFIRKPFDTDELLARVRSLLRLKHSIDAQKQMARQREDFVSRLTHDLRTPLVAADRMLNLFLQETFCKISPEMKKAIAAMVRSNNNLLEMVNTLLEVSRFEAGKKTMNFESCSMYSIVEEVVQELSPLAEERDLQLEFKNNLTEESKDKSAVNGDRLELRRVVSNLIGNAIKFTDEGQIEVRLSEFTSNAGEEWVKVDVEDTGYGIAEEDKTTIFERFRSGKNKRSGSGLGLHLSNRIAETHNAKIEFSSELGKGSIFTVVLPKASED
>NC_019678.1|WP_015116420.1|294186_295470_-|response-regulator
MDEKLKILIIEDDEIARTKILRAFNNYGLEQKQLEIVASHKGIDTFEDNYFDFVFLGNCGSHAQAIDLLKELTNFKKLVPIIAIVENNDELSAKQFIEAGAIDYLKKSSFSKEILESALRNALRIYGIQAQLNRLHQQLEQNNKLILNQKQQIEQQQQQIAIQKIKLTEVFELKSQFLATISHELRTPMNAIIGFSQLLLRPKCGIISKPQKDMVERILNNGKNLLMLLNEVLDYSKLQAEKLELKPERFDLAKLVKVTVADMHSFAEAKKLSVNVDISLENPTLYNDSLRVRQILNKLLSNAIKFTPNGCVEIKVTDISDNNIELVVADTGIGIAPENIQHIFEPFKQLDQSTNRKFEGTGLGLSIVQALVRMMDGKITIESELGQGALFRIELPRQVSSVLDREIAKKNLDLSSRRLMSHQKGEY
>NC_019678.1|WP_015116421.1|296918_297638_+|response-regulator-transcription-factor
MSEISIVLIEDHDLTRMGIKAALQANSELQVIGEAANGTRGLKMLESMKPDVALVDIGLPDIDGIELTRKFREYQSSVNDTSTKILVLTMNHTDDTVLAAFAAGADSYYMKDTSIDKLTEAIHSTYSGNSWIDPAIANIVLQQIRQEISDEQISAQAKTVKIEALSSEYEQVLETYPLTQRELEILELIVAGKSNGEIAEQLYITVGTVKTHVRNILNKLCADDRTQAAVRALRSGLVT
>NC_019678.1|WP_015116422.1|297836_298187_+|hypothetical-protein
MNYETAHQFLLNQTIASESNSDALLNRMRQGKPPIPGQITSILLALKVVFEALKDSNLLERELIYALYLLTVKAQQLFAAGLKAGVDWPPLFKEDLLRIANATESIFSGEWHNVHQ
>NC_019678.1|WP_015116423.1|298428_299022_-|hypothetical-protein
MIKKSLLQLLILPLAFVISSPGAAKALPGQSMEDVELWIKAHPTLSPRSGERFLVTKTDTAAQRFSFQAMVSAPGKLTFSNNRSKSRTERISMYDAINGMSVDKLKESLRVIYGLDVYQDYKGARVIYEYPNQSAINAARFARTPVREALKGELRVGSRYAYWVEVARGKNGKAFTGQMTVFLKSDLDKLEEELRNR
>NC_019678.1|WP_015116424.1|299484_300513_-|alcohol-dehydrogenase-catalytic-domain-containing-protein
MIAALLYGKEDLRLETVADPTPVDGEVVIKVGAATTCGTDLKVWLRGGHAKMLKPPTLFGHEAAGEIVSVGKGVTNWKIGDRVVANNSAPCMNCFFCKRQEYSLCPNLTWNNGTFAQYLKIPAPIVKHNLLKIADNLPLELAAMTEPLACVLHGVARSNVKPGDTVVVLGDGAIGLMFVAKLAGDCSAQVLLFGGNEQRLKIAEKLGAAKTFNYHQVADISATVKEFTQDFGADVVIEATGVPSAWETAITCARPGGTVNLFGGCPRDSTITVNTEQLHYSELTLKGVFHNTPEYVKQALSLISSRKIPFELLITQNRHLKDLEQVFNDMRQRKVVKVAISS
>NC_019678.1|WP_015116426.1|300963_302031_-|glycosyltransferase-family-4-protein
MRIAQVAPLRERVPPPSYGGIELVVSHLTDELVRRGHEVTLFASGDSLTEAKLEAVCDRALRLDPNVINYDAYELLELSQVYQRAAEFDVIHSHLGVLTLASAGLVTTPTVHTLHHSFNPDTAKIYTHHYKQPYISISNAQRKIDLNYIGTVYNGIDENNYPFVVEPENPPYLAFLGRFSPQKGPHHAISIAKQTGWHLKMAGKVDDLDRKFFEQEVAPYIDGKQIQYLGEVSHNEKAELLGRASVTLFPITWEEPFGLVMIESMATGTPVIATNMGSVPEVVKHGVSGFICQSHEDMASLIPQALQLSRYSCRKYVEDTFTIGKMVDGYEAIYRKIIENRIQKNGFIHSTKIKC
>NC_019678.1|WP_015116427.1|302869_305056_-|polysaccharide-biosynthesis-tyrosine-autokinase
MESQESSLSLDKYWQVLKRRWVPGIAAFFPVFLLSLLSSSLKKPTYIAEGKLLFQRTDTTSSLTGLGTEIGKLESVGQDSKSSPLQTEAEVIRSVPVVKKTIKELDLRGEDGRILEYGDFLEKLTVNDIAKTDILQVSYKDNQPQQAAKVVNTLMAAYLEHNVSSRRKAATSAREFIEKQLPQAEAIVSKAEAELARFKEKNKVYALQEEASKSIEVLSNLQGQIGEIKTKLADISARSQQIRNQLDINSQQALNMNSLNQAAGVQDILKEVQQVESQLTARRTVLKNTHPEIIALESKFNALKSLLQNRIRQTVGVDAQQLDGRLQEGELKQRLAGELVDLESTSVGLTNQLAVLSELQTSYKQRLENLPKLELQQRELDRKVEAAQSTYSLLLKKLQETSIAENQNIGNASRVSEALVPQEPVSSPLINYLSASLLGMLVSLATMYLLESQDKSIKTIEEAKELTGLTLLGVIPDFSKPKKSLLSKQDLEPAYPTLMVRDAPRSPISEAFRMLRANLKFMSADKELKVIVVTSSVPQEGKSTVAANLATSMAQMERRVLLIDGDLHRPSQHHIWELPNAQGLSNVIVGQVEVMAAIKKGMDNLDVMTCGAVPPSPASLLDSKRMASLVESFRSYYDYVIIDAPSLNLAADAATLGQMADGVLLVVRPGVVDSVNAAFACEMLEKSGQNVLGQVVNGVVPKNERHINYYYSQEYPEENMTTIETVKI

Crispr_ID: NC_019678_5

• CRISPR_ID: NC_019678_5
• CRISPR_location: 1609105-1609203
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 1 spacers

Consensus repeat of NC_019678_5

Consensus_repeat	Method
AGAGGGATGTCCGAAGCAGACTTTCAC	CRISPRCasFinder

spacers of NC_019678_5

>5.1|1609132|45|NC_019678|CRISPRCasFinder
CACTTCTATTTCTTCTGCCTCCTCCTTACCTTCTCTTTAACAAGA

CRISPR arrays and Neighbor proteins around NC_019678_5

CRISPR arrays

The CRISPR arrays of NC_019678_5

>merge|NC_019678|5|1609105-1609203|CRISPRCasFinder
AGAGGGATGTCCGAAGCAGACTTTCACCACTTCTATTTCTTCTGCCTCCTCCTTACCTTCTCTTTAACAAGAAGAGGGATGTCCGAAGCGGACTTTCAC

>NC_019678|5|5|1609105-1609203|CRISPRCasFinder
AGAGGGATGTCCGAAGCAGACTTTCAC	CACTTCTATTTCTTCTGCCTCCTCCTTACCTTCTCTTTAACAAGA
AGAGGGATGTCCGAAGCGGACTTTCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015117417.1|1611513_1612233_-|cytochrome-b	unknown	unknown	gnl|CDD|376516
NC_019678.1|WP_083894117.1|1596704_1599170_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|315987
NC_019678.1|WP_015117412.1|1603068_1604169_+|glycosyltransferase	unknown	unknown	gnl|CDD|340831
NC_019678.1|WP_015117407.1|1600920_1601214_+|plasmid-maintenance-system-killer-protein	unknown	unknown	gnl|CDD|226079
NC_019678.1|WP_044291560.1|1614466_1614781_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015117414.1|1605480_1609026_-|WD40-repeat-containing-protein	unknown	unknown	gnl|CDD|238121
NC_019678.1|WP_044290782.1|1615586_1616516_+|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|237771
NC_019678.1|WP_044290781.1|1594024_1596292_+|FdhF/YdeP-family-oxidoreductase	unknown	unknown	gnl|CDD|273765
NC_019678.1|WP_015117408.1|1601228_1601534_+|HigA-family-addiction-module-antidote-protein	unknown	unknown	gnl|CDD|274228
NC_019678.1|WP_015117423.1|1618840_1619296_+|transcriptional-repressor	unknown	unknown	gnl|CDD|366663
NC_019678.1|WP_015117409.1|1601548_1602127_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NC_019678.1|WP_015117416.1|1610332_1611457_-|RNA-methyltransferase	unknown	unknown	gnl|CDD|236981
NC_019678.1|WP_015117410.1|1602138_1602705_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_019678.1|WP_083894043.1|1614822_1615206_-|DUF4433-domain-containing-protein	unknown	unknown	gnl|CDD|373093
NC_019678.1|WP_015117422.1|1617039_1618299_+|RNA-polymerase-sigma-factor-SigC	unknown	unknown	gnl|CDD|236067
NC_019678.1|WP_015117406.1|1600393_1600753_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015117419.1|1613299_1614103_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NC_019678.1|WP_015117415.1|1609488_1610283_+|SnoaL-like-polyketide-cyclase	unknown	unknown	gnl|CDD|377824
NC_019678.1|WP_015117413.1|1604509_1605400_+|lipoyl-synthase	unknown	unknown	gnl|CDD|235493
NC_019678.1|WP_015117418.1|1612403_1612781_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_083894117.1|1596704_1599170_-|tetratricopeptide-repeat-protein	gnl|CDD|315987	pfam13424, TPR_12, Tetratricopeptide repeat.	6.21085e-17
NC_019678.1|WP_015117412.1|1603068_1604169_+|glycosyltransferase	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	2.75676e-35
NC_019678.1|WP_015117407.1|1600920_1601214_+|plasmid-maintenance-system-killer-protein	gnl|CDD|226079	COG3549, HigB, Plasmid maintenance system killer protein [General function prediction only].	2.75772e-25
NC_019678.1|WP_015117414.1|1605480_1609026_-|WD40-repeat-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	7.86673e-70
NC_019678.1|WP_044290782.1|1615586_1616516_+|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	gnl|CDD|237771	PRK14619, PRK14619, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional.	0
NC_019678.1|WP_044290781.1|1594024_1596292_+|FdhF/YdeP-family-oxidoreductase	gnl|CDD|273765	TIGR01701, Hypothetical_protein_Rv2900c/MT2968/Mb2924c., oxidoreductase alpha (molybdopterin) subunit. This model represents a well-defined clade of oxidoreductase alpha subunits most closely related to a group of formate dehydrogenases including the E. coli FdhH protein (TIGR01591). These alpha subunits contain a molybdopterin cofactor and generally associate with two other subunits which contain iron-sulfur clusters and cytochromes. The particular subunits with which this enzyme interacts and the substrate which is reduced is unknown at this time. In Ralstonia, the gene is associated with the cbb operon, but is not essential for CO2 fixation.	0
NC_019678.1|WP_015117408.1|1601228_1601534_+|HigA-family-addiction-module-antidote-protein	gnl|CDD|274228	TIGR02607, Virulence-associated_protein_I, addiction module antidote protein, HigA family. Members of this family form a distinct clade within the larger family HTH_3 of helix-turn-helix proteins, described by pfam01381. Members of this clade are strictly bacterial and nearly always shorter than 110 amino acids. This family includes the characterized member HigA, without which the killer protein HigB cannot be cloned. The hig (host inhibition of growth) system is noted to be unusual in that killer protein is uncoded by the upstream member of the gene pair. [Regulatory functions, DNA interactions, Regulatory functions, Protein interactions, Mobile and extrachromosomal element functions, Other].	4.86296e-39
NC_019678.1|WP_015117423.1|1618840_1619296_+|transcriptional-repressor	gnl|CDD|366663	pfam01475, FUR, Ferric uptake regulator family. This family includes metal ion uptake regulator proteins, that bind to the operator DNA and controls transcription of metal ion-responsive genes. This family is also known as the FUR family.	4.46852e-47
NC_019678.1|WP_015117415.1|1609488_1610283_+|SnoaL-like-polyketide-cyclase	gnl|CDD|377824	pfam07366, SnoaL, SnoaL-like polyketide cyclase. This family includes SnoaL a polyketide cyclase involved in nogalamycin biosynthesis. This family was formerly known as DUF1486. The proteins in this family adopt a distorted alpha-beta barrel fold. Structural data together with site-directed mutagenesis experiments have shown that SnoaL has a different mechanism to that of the classical aldolase for catalyzing intramolecular aldol condensation.	0.00100162
NC_019678.1|WP_015117417.1|1611513_1612233_-|cytochrome-b	gnl|CDD|376516	pfam01292, Ni_hydr_CYTB, Prokaryotic cytochrome b561. This family includes cytochrome b561 and related proteins, in addition to the nickel-dependent hydrogenases b-type cytochrome subunit. Cytochrome b561 is a secretory vesicle-specific electron transport protein. It is an integral membrane protein, that binds two heme groups non-covalently. This is a prokaryotic family. Members of the 'eukaryotic cytochrome b561' family can be found in pfam03188.	0.000690581
NC_019678.1|WP_015117410.1|1602138_1602705_-|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	9.04567e-37
NC_019678.1|WP_083894043.1|1614822_1615206_-|DUF4433-domain-containing-protein	gnl|CDD|373093	pfam14487, DUF4433, Domain of unknown function (DUF4433). This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 201 and 230 amino acids in length. There is a single completely conserved residue E that may be functionally important. This family is distantly similar to pfam01885 suggesting these may be ADP-ribosylases.	0.000595473
NC_019678.1|WP_015117422.1|1617039_1618299_+|RNA-polymerase-sigma-factor-SigC	gnl|CDD|236067	PRK07598, PRK07598, RNA polymerase sigma factor SigC; Validated.	0
NC_019678.1|WP_015117409.1|1601548_1602127_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	1.63074e-46
NC_019678.1|WP_015117419.1|1613299_1614103_-|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.22295e-32
NC_019678.1|WP_015117416.1|1610332_1611457_-|RNA-methyltransferase	gnl|CDD|236981	PRK11783, rlmL, bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL.	1.97099e-151
NC_019678.1|WP_015117413.1|1604509_1605400_+|lipoyl-synthase	gnl|CDD|235493	PRK05481, PRK05481, lipoyl synthase; Provisional.	0

Protein sequences

>NC_019678.1|WP_015117414.1|1605480_1609026_-|WD40-repeat-containing-protein
MTVQRRGRGVVLTDGGWEKLENSLHEWENTNNSDKPYTIEALIEVTQLDPATISKVLRREIAVDRRTLERFFRGFNLELDKSDYTKLVLSKNNQQNQYFCSEVPDVSIFFGRAEELNILQKWIVIDCCRLITLVGIGGIGKTSLSAKVIQNLRNNFDLTIWFSLRNAPPPLEIITNLLQVLSNGEEVDLARNISVLINKLIEYLQNQRSLIVFDNVDAVFCDSNYAGNYLSGYESYGELFQKLGETSHQSCLLMTSREKPKEISAIEGKELPARCLQISGLGISEVKQIFQGKGITNATDSNWQQLTINYGGNPLYLKFIASTVLDLFDGNIAEFLVQSNRSRVFGDVRNLIARQFNRLSELEQSLLYWLAINQDAVDLKELLSDLVSQPFSLLEILESLNRRSLIEKNKSKFSLQSVVMEYVTTNYIDQISQEISSGDISLFKSHALLKATSPDYIQDIQKRLIITPILEGLEVILGSQHQVETSLRNILSHFRGKSPLLTGYAVGNIINLLSHLSSEISNQDFSNLNIRQANLQGISLNNVDFSNSHFTQTTFSNTFGIIFSLAFNTTEEFLVTGSIDGEVCLWKWQTNQQVFKNHGHKTIVESVAFSLDSLKIASSSRDRSIKIWDASTGECILTLESPNQHTVKNLVFHRDGSKLFGYSNRSIISWDLNTGNSRILIESQSRICSLILSEDDILIFGCDDGAIFVWDINTEELIDRFSTNSGIILSLGHTKENDILTCGIRDKIVTVWNLNNSESIEIQSQSYNISLIDISNNGKFLATGSGEKTIKIWDIDTGLYLQSLSGHLSEINAIAFGSKNQILATASVDRTVKIWDVTTGKCLKTLQGRADYVHSAILSSDNRTIISGSQHTINFWDIDSQQCIYTLFKTKDWLSSLIVSQDEKTIACANIGNEDNVIRIWQINDLNNCLTTSNKIPSKILKGHDDSIWSFAFNSDGKKIVSGSSDRTVKVWDSDTAQCLKTFYGHNRPVLSVSFSPDENIIASCGGHSIIKLWNVETGECFQTIQERASYIIKFNCNGLILASGHTSGIVKLWDTNSAKCLQTLGNFGKPIISLAFSYDGNFIAYGSYDGTVTVWDINKNKSIAILQEKFSSPWSLTFSKDSNLLAVGRDSEIIQLWDIKAGKIVAFFQGDRHAEKVNITGVTGLTAARIANLIELGAYN
>NC_019678.1|WP_015117413.1|1604509_1605400_+|lipoyl-synthase
MTVKPDWLRVKAPQWERVGNVKETLRDLSLNTVCEEASCPNIGECFKAGTATFLIMGPACTRACPYCDIDFEKKPQPLDPTEPSRLAEAVRRMKLNHVVITSVNRDDLPDEGASQFVRCIEAVRTISPKTTIEVLIPDLCGNWEALEIILKAQPEVLNHNTETVPRLYKRTRPQGDYQRTLELLKISRQIAPWIYTKSGIMVGLGETDEEIRQVMQDLRAVDCDILTIGQYLQPTQKHLKVGDFIHPEQFAGWKKYGEEIGFLQVVSSPLTRSSYHAEQVRELMKQYPREKTSELI
>NC_019678.1|WP_015117412.1|1603068_1604169_+|glycosyltransferase
MKILIQHRHYENEISGVLTYINSIIPGLEATGTEIKTISSREDNLQKWLSLIFWADIVHMNSNDLLFAILCKALGKKIIIKYHYLFYQSTHTNYEEMTFTQRIKAELKRTLPKTDYPLKWKLYTFVKWAKLAARISTAFFADYHAACSDFLGDSCAFPWQVHTLYYPIELKHKNKFKAVGKLSKPYKFVFVGRLDGDKGVDILLRAIKIVQTQNYQFQVTIVGDGAQANQLKALASELDILNSVNFLGKIPNTEVTSKIEDALALVVPSRWQEPAGYVVLEASSVQTCSIVSKMGGLPEVAGPHNLFFENEDAQGLANCMKECLDNPEKTVERGLLSSEYVSKYFSSQGAAQEFMDVCTQLSPQTS
>NC_019678.1|WP_015117410.1|1602138_1602705_-|Uma2-family-endonuclease
MQSVINFLTIKEYLELEHNSEIRHEYVDGEVFAMAGASEEHNLIVTNIIALLRPHLRGTPYRTFASDMKVKVKVQKADIFYYPDVLVTCDPNDNERYFKTSPKLIVEVLSNSTKTIDKREKRLNYQNIQSLQEYVLISQDEIKVEIYRQDSQVNWLMQILGKNDELRLDSIDLTITMAEIYEDVVKIL
>NC_019678.1|WP_015117409.1|1601548_1602127_-|Uma2-family-endonuclease
MTALSLQIPPSLKFTDEEFEQIVAFNQELRLELTAEGKLIIMSPTGGETGNRNFEIYIDLGVWNRKNKLGKAFDSSTGFKLPNGATRSPDASWIKIERWDALTPQQRKKYLPLCPDFAVELVSESDDVEDTRKKMLEYIENGLRLGWLINPKDKLVEIYRIGKEVEILDSPDSLSGEDVLIGFSLDLEVIFG
>NC_019678.1|WP_015117408.1|1601228_1601534_+|HigA-family-addiction-module-antidote-protein
MKIPKFRPPTHPGEILLKDFLEPMGITQRQLADALHVPYQRINELVNQKRGITPSTAIRLSKFFGNSSQFWLNLQQNWELYHVMKEEEEEIKTIFQFKSAG
>NC_019678.1|WP_015117407.1|1600920_1601214_+|plasmid-maintenance-system-killer-protein
MIVSFKNQGTEDVFDGNDSKEARKQCPINCWEVARRKLDQLNAASSLDDIKVPPGNRLEALKGERKGQYSIRINDKYRICFIWTVQDASEVEIVDYH
>NC_019678.1|WP_015117406.1|1600393_1600753_-|hypothetical-protein
MPEQNLIGLSELIEQVKQELLTKAPENENDIPLLSVDSVELELQVTVKNEAKGGIKIYVLELGGGNSQDDVQKVKVKLSPLLNKEQMLGIYKKKYPERWNELLETSTEGGMKGNEQPGF
>NC_019678.1|WP_083894117.1|1596704_1599170_-|tetratricopeptide-repeat-protein
MGVEGNQWYRPVLYLRWQDNQGGQLFALPSIDTSPKSIPQNLPRSGVIKFVGREEVLETLHQQLQENERVAISAITGMGGIGKTELALQYGDRHWKQGTYSGGICWFPVRDEDVGIKIIDFAREIGLQPPDNFYLLNKVKYCWRNWQAGDVLVVFDDVREYQQIKDYLPPNEPRFKILVTTRQQWLGQSFKRVILEVLEENAALELLVSFVGEERVDLEKEEAKKLCADLGYLPLGLELVARYLQRKPNLSLIKMCQRLALEHRSLIERSGDMTAKLGVKAAFELSWRELKEETQELACLLSIFALALIPWELVEQCLPEEDKEDLEDIRDDFLVDFSLLEDKGENSYQLHQLIREFLIGKREELADVEDMKRGFCYVIAPIGQKISNTPTQSDILELTLEIPHLIETVIHQKDYLADEDLIIPFTGLGKFYKGQAAYNKALFYYEKCLAISKERFGEEHYDVATSFNNLAEVYYSLGNFQEPESLYLKALEIWKKLLGEEHHDFATGLNNLAKLYNSQGRFEQAEPLYLKALGIWKKLVGEEHHDFATGLNNLAVLYYSKGRYQQAEPLYKQALQIRKKLLGEEHPNVVQSLNNLAVLYNSQGRYSEAEPLYKQALEMGIKLLGESHPDVALSLNNLAALYDSQERYSEAEPLYLQALQVRKKLLGEEHPDIAQNLNNLAVLYSSQGNYSEAESHCKQALQMRKKLLGESHPEVANSLNNLATLYRLQKRYSEAEILYLQTLQMRKKLLGESHPDFVTSLNNLAGLYNLQRRYQEAQTLYKQALNISEQLLGVGHPKTMMVRENYASCLKSMVVEKKYQA
>NC_019678.1|WP_044290781.1|1594024_1596292_+|FdhF/YdeP-family-oxidoreductase
MNKDNSNSQSTPIFNNANENTPDMGGGLPIIGYWAEHTLSPEGVKLWKTLLHKSACLACAWGTGGQKGGFTNEEGEKLQRCMKSVESIAAEIQPAIPKQFFEQRSIEELQQLTSKEADRLGRWSFPVILRSGSSHYERISWNEIYSICDKAFAQTPERIASYSSGRSSNEAAFLLQLMMRTLGSNNLADCSDLCHAPSSFGLKQTLGTTTSVVSLESLKQADCIVLAGSNAAYNHPRLMNELIKLRERGGKVIVINPMKEVGLVKFASPAFIKSLFTGSDIACAYLQPIPGSDVALFMGIQKALLAKGKIKQDFLQAYTENWQAVISHIENTAWETITTACGVSQTEIETAANIISNSQKVVFAWAMGITQQKNGVDNIYSIVNTALMTGNIGKEGAGVMPIRGHSNVQGFGSMGVTVRLKKEIQQALEKLLGRSLSKVKGYDTHALIEAADEGKVDTLICVGGNLYAANPDSTKVRRALNKIETIIYLATKPNLGHFHGLAGKNTIIIPVFNRFENPHKTTVESGNNFVRLNDEGETHLKKADLISEVDFLAELAHRIHGEYPVNWRKLQDTKYVRQLIAQTIPGYEKIGEIDDTESEFTISGRILKNPKFSTPSGKAQMFITPLPELKLPQIKDFDVADSTQGIVIVLMTGRSYAQHNTVVYQTEDKYRGIPHRNCILMNPKDVEKAGFEQHQRVAVRGNVGELENVEIIFGDVREGAGVMFYPEVNVIFKAEVEERCGTPAFKRVPVLVYGG
>NC_019678.1|WP_015117415.1|1609488_1610283_+|SnoaL-like-polyketide-cyclase
MTNINTENLPLWVQNRDTVLKANKNVQWRYDKQPDYTKSNQNFAKESKQNHPANSLEALVQNLVRTFDIEANFKTDPQQWISVVQDKFRMSTNGGTNYKLEDLVESGTYKLLIGDTQHYKASEENFETSTNLFHSAFPEGFLWEVVEVYSAPPTIAVKWRHWGHFRGAYKDYVPTGETIEIIGMSIVKVTDDLKILSLEHYYDNTKFLDKLTSGGKTSGGAKQTPPSLQQKFWGFIKQLLRPQLKPATVNLQTSRCPFANLINK
>NC_019678.1|WP_015117416.1|1610332_1611457_-|RNA-methyltransferase
MNEYFATVARGLEDLAAKELEQLGAKSVEPGFCGVEFEGDRTLLYRVNLWARLPFRILFKVIKFPCKNAKELYKGIQTIEWQDYLTPEDTLAVNATGKNDELNHTHFTALQVKNAIVDQQQEVFGERSDVELYNPDLRINVHIRNDFCTVSLDSSGKSLHRRGYRPAVGAAPLKESLAAALIELSGWQPDQMFYDPLCGSGTLPIEACLKSLNIAPGLFRESFGFETWRDFDLSLLEQLIAEAEACQLDTLPASIWGSDNNEDVIEQASVNAVNSGVENHIYFSQMELADVAAPADSGVLFCNPPYGERLGRDSDLGQFYKLLGDVMKQRFKGWTAFVLSGNKELAKYIGLKSSQRIAVYNGTLPCQLMKYELY
>NC_019678.1|WP_015117417.1|1611513_1612233_-|cytochrome-b
MSAKFHQPYQPLLLRILHALIGLFTIGAIITAFWTYDVFDGRWGTISLPKFTEIEGIHGTFGVWTLLIFPLFAIYAFHRGQRRLIQPDSFKNLTKFGEPMWWYSLHRLVNTLSILAVTFAVCSGKMMDEKWLPQGELNHSWYYAHLISWLILVICLALHVLMSIKVGSVPLILSMINLRFRSKDSPGLWQENFYSWRSNFNMVIVKQWLSSLSLLKVIEIFVFIAIISALVASVIKEIS
>NC_019678.1|WP_015117418.1|1612403_1612781_-|hypothetical-protein
MTTEQIINFISGHLDLTQAEFDKHYRQQINNALKKNQGFVVGDARGTDTLAQQYLLGKTKAVVVYHMFENPRNNAGFPTRGGFQSDAERDEQMTRDSHQDIAWVRTGRENSGTQKNLDRRLGNMN
>NC_019678.1|WP_015117419.1|1613299_1614103_-|alpha/beta-hydrolase
MAETFKLNIGSAELAVECSGEGKPLIFLHAGVADKRMWHYQMAGLNDSYQVVAYDRRGFGETTTADQAFSHIEDLRKVLDKLEVSNTFLVGCSQGGRIAIDFTLAYPQRVTKLVLISTAISGAPAPETFAPNIQARINTLKEAEETNDLARVNAIEANLWLDGATSQKGRVNSALRELFLDMNGIALGMPELTQEIEPNNAYERLSVLSLPVLVIWGELDFPHIKQRCQYIVDTIPNAWGEEIPGTAHLPNFEKPEKINKLLRDFLG
>NC_019678.1|WP_044291560.1|1614466_1614781_-|hypothetical-protein
MAKRPLFIPNKKCFTFVKESLIEFKWHPGFAKVQAQKSIASLHEAAAEAKIAPVLEISSKSNDEVGVSLSAFNLKMIKNEKSLSVECAYQGSKVFANGGPFSDL
>NC_019678.1|WP_083894043.1|1614822_1615206_-|DUF4433-domain-containing-protein
MHGLNQAVLWELDCKFYQENAASNNAKENILEMRTQAITQPDVLKNMFSDYGRIKREILEIPSNFTTYPQAEVLVFNQIDAQYIDAVHFYNLNVGNCWAKQNPGNYLQKFYGECRYYFSPRQDWEMW
>NC_019678.1|WP_044290782.1|1615586_1616516_+|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase
MANQKTVAILGAGAWGKALTTLAQINAHDVRIFSRRGSQTLEQTVEGADIILSAVSMKGVRDVASQLKSLSVSPQTIFVTATKGLDPQTTCTPSQIWQDNFPDNPVVVLCGPNLSKEITKELPAATVVASKIESAAESTQLVFNSTRFRVYTNSDPLGVELGGTLKNVMAIAAGVCDGLQLGTNAKAALMTRGLTEMVRIGVHWGAKPETFYGLSGLGDILATCNSPLSRNYQVGYQLGQGKTLTEILSQLEETAEGVNTAEVLVHRAKQQNISMPITQEVYRLLKAEVTPRQALMDLMKRDIKPEYNN
>NC_019678.1|WP_015117422.1|1617039_1618299_+|RNA-polymerase-sigma-factor-SigC
MPATSFYADADAAYDTQKSRQDLEPEITADDADAPADEDLEQLEMASSETANVSASTKTRSTDLVRLYLQEIGRVRLLGRDEEVSEAQKVQRYLKLRILLSEAASKGDELLAHYLKIIEAQERLTSELGHRPSMKRWANTAGIEESELKGALSQGKRRWAETAKLTVQELEQIQTQGLQAKEHMIKANLRLVVSVAKKYQNRGLELLDLVQEGTLGLERAVEKFDPTKGYRFSTYAYWWIRQGITRAIATSSRTIRLPVHITEKLNKIKKAQRKIAQEKGRTPTLEDLAVELEMTPAQVREVLLRVPRSVSLETKVGKDKDTELGELLETDGVTPEEMLMRESLQRDLQNLLADLTTRERDVILMRFGLADGHPYSLAEIGRALDLSRERVRQIESKALQKLRQPKRRNLIRDYLESLS
>NC_019678.1|WP_015117423.1|1618840_1619296_+|transcriptional-repressor
MTIYTTASLKAELNERGWRLTPQREVILHIFQELPQGEHLSAEDLYQRLQGDNEGISLSTIYRTLKLMARMGILRELELGEGHKHYELNQPYPHHHHHLICVRCNTTTEFKNDSILKIGLKTSQKDGYHLLDCQLTIHGVCPKCQRALMPL

Crispr_ID: NC_019678_6

• CRISPR_ID: NC_019678_6
• CRISPR_location: 1975044-1975149
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 1 spacers

Consensus repeat of NC_019678_6

Consensus_repeat	Method
AAGGAGAGGGGCTGGGGGTGAGGT	CRISPRCasFinder

spacers of NC_019678_6

>6.1|1975068|58|NC_019678|CRISPRCasFinder
TTCGAGCAATGTAGCAAGAAAAGATTTAGAAGTAAGGTAATTCTCCCCTCTCCTTGAC

CRISPR arrays and Neighbor proteins around NC_019678_6

CRISPR arrays

The CRISPR arrays of NC_019678_6

>merge|NC_019678|6|1975044-1975149|CRISPRCasFinder
AAGGAGAGGGGCTGGGGGTGAGGTTTCGAGCAATGTAGCAAGAAAAGATTTAGAAGTAAGGTAATTCTCCCCTCTCCTTGACAAGGAGAGGGGTTGGGGGTGAGGT

>NC_019678|6|6|1975044-1975149|CRISPRCasFinder
AAGGAGAGGGGCTGGGGGTGAGGT	TTCGAGCAATGTAGCAAGAAAAGATTTAGAAGTAAGGTAATTCTCCCCTCTCCTTGAC
AAGGAGAGGGGTTGGGGGTGAGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015117699.1|1963455_1964514_-|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl|CDD|234761
NC_019678.1|WP_015117714.1|1981052_1981841_-|rod-shape-determining-protein-MreC	unknown	unknown	gnl|CDD|237560
NC_019678.1|WP_015117716.1|1983459_1983819_+|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|180986
NC_019678.1|WP_015117704.1|1969481_1969862_-|DUF2834-domain-containing-protein	unknown	unknown	gnl|CDD|371414
NC_019678.1|WP_015117707.1|1971478_1975021_+|methionine-synthase	unknown	unknown	gnl|CDD|273959
NC_019678.1|WP_015117701.1|1966834_1968148_+|ATP-binding-protein	unknown	unknown	gnl|CDD|379114
NC_019678.1|WP_015117712.1|1978895_1980095_-|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	unknown	unknown	gnl|CDD|273015
NC_019678.1|WP_015117703.1|1968811_1969219_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015117709.1|1975680_1976232_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015117711.1|1978557_1978797_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015117708.1|1975231_1975600_+|DUF559-domain-containing-protein	unknown	unknown	gnl|CDD|238509
NC_019678.1|WP_015117713.1|1980390_1981029_-|rod-shape-determining-protein-MreD	unknown	unknown	gnl|CDD|225444
NC_019678.1|WP_015117717.1|1983985_1984732_-|DUF541-domain-containing-protein	unknown	unknown	gnl|CDD|225516
NC_019678.1|WP_157229394.1|1961674_1962964_+|phosphopyruvate-hydratase	unknown	unknown	gnl|CDD|234617
NC_019678.1|WP_063721479.1|1969967_1970792_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|375319
NC_019678.1|WP_015117702.1|1968131_1968800_+|RloB-domain-containing-protein	unknown	unknown	gnl|CDD|379341
NC_019678.1|WP_044291587.1|1964785_1966495_+|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase-RibB/GTP-cyclohydrolase-II-RibA	unknown	unknown	gnl|CDD|236465
NC_019678.1|WP_015117706.1|1970912_1971386_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl|CDD|376852
NC_019678.1|WP_015117710.1|1976431_1977298_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223999
NC_019678.1|WP_015117715.1|1982083_1983091_-|rod-shape-determining-protein	unknown	unknown	gnl|CDD|237562

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015117699.1|1963455_1964514_-|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl|CDD|234761	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated.	0
NC_019678.1|WP_015117714.1|1981052_1981841_-|rod-shape-determining-protein-MreC	gnl|CDD|237560	PRK13922, PRK13922, rod shape-determining protein MreC; Provisional.	1.08907e-60
NC_019678.1|WP_015117716.1|1983459_1983819_+|single-stranded-DNA-binding-protein	gnl|CDD|180986	PRK07459, PRK07459, single-stranded DNA-binding protein; Provisional.	3.26008e-65
NC_019678.1|WP_015117704.1|1969481_1969862_-|DUF2834-domain-containing-protein	gnl|CDD|371414	pfam11196, DUF2834, Protein of unknown function (DUF2834). This is a bacterial family of uncharacterized proteins.	3.44191e-30
NC_019678.1|WP_015117707.1|1971478_1975021_+|methionine-synthase	gnl|CDD|273959	TIGR02082, Methionine_synthase, 5-methyltetrahydrofolate--homocysteine methyltransferase. This family represents 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13), one of at least three different enzymes able to convert homocysteine to methionine by transferring a methyl group on to the sulfur atom. It is also called the vitamin B12(or cobalamine)-dependent methionine synthase. Other methionine synthases include 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (MetE, EC 2.1.1.14, the cobalamin-independent methionine synthase) and betaine-homocysteine methyltransferase. [Amino acid biosynthesis, Aspartate family].	0
NC_019678.1|WP_015117701.1|1966834_1968148_+|ATP-binding-protein	gnl|CDD|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	1.60049e-32
NC_019678.1|WP_015117712.1|1978895_1980095_-|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	gnl|CDD|273015	TIGR00326, eubact_ribD, riboflavin biosynthesis protein RibD. This model describes the ribD protein as found in Escherichia coli. The N-terminal domain includes the conserved zinc-binding site region captured in the model dCMP_cyt_deam and shared by proteins such as cytosine deaminase, mammalian apolipoprotein B mRNA editing protein, blasticidin-S deaminase, and Bacillus subtilis competence protein comEB. The C-terminal domain is homologous to the full length of yeast HTP reductase, a protein required for riboflavin biosynthesis. A number of archaeal proteins believed related to riboflavin biosynthesis contain only this C-terminal domain and are not found as full-length matches to this model. [Biosynthesis of cofactors, prosthetic groups, and carriers, Riboflavin, FMN, and FAD].	8.81306e-144
NC_019678.1|WP_015117708.1|1975231_1975600_+|DUF559-domain-containing-protein	gnl|CDD|238509	cd01038, Endonuclease_DUF559, Domain of unknown function, appears to be related to a diverse group of endonucleases.	1.00594e-27
NC_019678.1|WP_015117713.1|1980390_1981029_-|rod-shape-determining-protein-MreD	gnl|CDD|225444	COG2891, MreD, Cell shape-determining protein [Cell envelope biogenesis, outer membrane].	2.12812e-24
NC_019678.1|WP_015117717.1|1983985_1984732_-|DUF541-domain-containing-protein	gnl|CDD|225516	COG2968, COG2968, Uncharacterized conserved protein [Function unknown].	2.55605e-56
NC_019678.1|WP_157229394.1|1961674_1962964_+|phosphopyruvate-hydratase	gnl|CDD|234617	PRK00077, eno, enolase; Provisional.	0
NC_019678.1|WP_063721479.1|1969967_1970792_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	4.0685e-23
NC_019678.1|WP_015117702.1|1968131_1968800_+|RloB-domain-containing-protein	gnl|CDD|379341	pfam13707, RloB, RloB-like protein. This family includes the RloB protein that is found within a bacterial restriction modification operon. This family includes the AbiLii protein that is found as part of a plasmid encoded phage abortive infection mechanism. Deletion within abiLii abolished the phage resistance. The family includes some proteins annotated as CRISPR Csm2 proteins.	2.3821e-35
NC_019678.1|WP_044291587.1|1964785_1966495_+|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase-RibB/GTP-cyclohydrolase-II-RibA	gnl|CDD|236465	PRK09319, PRK09319, bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase RibB/GTP cyclohydrolase II RibA.	0
NC_019678.1|WP_015117706.1|1970912_1971386_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl|CDD|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	0.000137517
NC_019678.1|WP_015117710.1|1976431_1977298_+|alpha/beta-hydrolase	gnl|CDD|223999	COG1073, COG1073, Hydrolases of the alpha/beta superfamily [General function prediction only].	9.77473e-24
NC_019678.1|WP_015117715.1|1982083_1983091_-|rod-shape-determining-protein	gnl|CDD|237562	PRK13927, PRK13927, rod shape-determining protein MreB; Provisional.	0

Protein sequences

>NC_019678.1|WP_015117707.1|1971478_1975021_+|methionine-synthase
MANSFLEHLRSPKRPVVVFDGAMGTNLQVQELTAEDFGGAEYEGCNEYLVHTKPEAVATVHRGFLAAGADVVETDTFGGTSIVLAEYDLADQAYYLNKAAAELAKKVCAEFSTPEKPRFVGGSMGPGTKLPTLGHIDFDTLKNAYVEQAEALWDGGVDLFIVETCQDVLQIKSALNAIEEVFAKKGDRRPIMVSVTMETMGTMLVGTEIAAVVTILEPYNIDILGLNCATGPDLMKPYIKYLSEHSPFIVSCIPNAGLPENVGGQAHYKLTPVELKMHLMHFIEDLGVQAIGGCCGTRPKHIEALAEIAKDLTPKDRKPQTEPAAASIYGTQPYDQDNSFLIIGERLNASGSKKCRTMLNDEDWDGLVSLGRSQVKEGAHVLDVNVDYVGRDGVRDMHELVSRLVNNITLPLVLDSTEWEKMEAGLKVAGGKCLLNSTNYEDGEERFLKVLELAKTYGAGVVIGTIDEDGMARTADKKFEIAQRAYRQALEYGIPAHEIFFDNLALPISTGIEEDRENGKATIESIRRIRQELPGCHVVLGVSNVSFGLNPAARIVLNSMFLHEAMQAGMDAAIVSASKILPLAKIEEEHQKICRDLIYDNRKFDGDICVYDPLGELTTMFEGVSAKRDKGVDVSLPIEERLKQHVIDGERIGLEDALKEAMEKYPPLDIVNIYLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAFLEPHMEKSEGEVDNAKGTFVIATVKGDVHDIGKNLVDIILSNNGYRVINLGIKQPVENIIQAYEEHKPDCIAMSGLLVKSTAFMKDNLETFNEKGITVPVILGGAALTPKFVNDDCQNTYKGKVIYGKDAFSDLHFMDKLMPAKSGNDWDDFKGFLGEFAEEEHSQNGNGNGHKGAEAKAVEDKPEEPKVIDTKRSEAVDIDTERPTPPFWGTKLLQGEDIPLEELFWYLDLQALIAGQWQFRKPKDQTKEEYQAFLAEKVYPILETWKKRVVEENLLHPQVIYGYFPTQAEGNTLHIYNPENHSEKVTEFEFPRQKSLRRLCIADFFAPKETGIMDVFPMQAVTVGEIATEFAQKLFSNNEYTDYLYFHGIAVQMAEALAEWTHARIRRELGFADEDPDNIRDMLAQRYRGSRYSFGYPACPNIPDQYKQLDLLKTDRINLYMDESEQIYPEQSTTAIITYHPVAKYFSA
>NC_019678.1|WP_015117706.1|1970912_1971386_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MIIKQHVNQDEGFVRSSIEEVRGNLLEALKTVVLAGKRIVLQQAGEEVAAIIPVKEFERLEYLEHELVPPIWEPYEEEYYEDEGGIHCVLVDEMEAEFDEIITEVTVYKELFGLLPPQHLSGKEFDTFAPVAIVMNIDKFWVSEYWISEKDRLKAFH
>NC_019678.1|WP_063721479.1|1969967_1970792_+|helix-turn-helix-transcriptional-regulator
MQSTSNQQTTFGNLLKHHRKLRNFSQLDLALASDVSQRHISFLESGRANPSQEMILQLATVLDIPLREQNVMLTTAGFAPIYSESDLSSPEFEPIRKALDFILLSQTHSPVLIMDRYWNLIQTNPVSQRLINWLIDSEDLHNRFYIDGKINLMRLMLHSQGLKPFVSNWEEIVSHLIKRVYREAIADDNNEQPRQLYQELMTYPDIPQLWKLSNSQSWQMPLLTVNFFKAGLHLNFFSAIATLGTPQDIMLQELRIETLFPADEITQKNLVELN
>NC_019678.1|WP_015117704.1|1969481_1969862_-|DUF2834-domain-containing-protein
MSNTTYQNQTSASSKLFSAKSLYLLLVIIGSIAPWSLILEFFIQNGFSIELLIQKEFDNYAAAAFGTDLLISALVFLCFSFVELKRLGLSRSRLLIYIAATFGVGLSCSLPLFLYFREGVLESKNS
>NC_019678.1|WP_015117703.1|1968811_1969219_-|hypothetical-protein
MKNLLFYLGFATILTHELDAMTQSEWKLLFILRSLPEQTASVAFIVLHIPLIAALLWLTNNESEVVKNWSRIALAGFMIIHSGLHKLLENSPNYTFNSTLSLGLIYGAGLLGLIYLILIFIFWLRKSDKSLTTNL
>NC_019678.1|WP_015117702.1|1968131_1968800_+|RloB-domain-containing-protein
MSKRGKNKNQLQRGKANKKRIKYILIVVEGQETEYNYFNSLKDDLKLKTTEIQVARASGGSPLDVVEKAKSLLQEKIRLSNKQGNPKYDEVFCVFDQDNQMKKYHQALIEAKNNNIQAITSIPCFEVWFLLHCCNTSSPFSDCKEVCKKLESEFKKLRFLKPKECYEKKNSDWYKILKPKLQNAIDNAEKLEKYQENNRENFNPSTKVHILVKILQNQKHFE
>NC_019678.1|WP_015117701.1|1966834_1968148_+|ATP-binding-protein
MLIEFSIENYRSIQERQTLSMVASKDEAMLDSNTFPTPNSKDELRLITNAVIYGANASGKSNLLRAIQTLRRLVVDSASKMQVGTKLPIESFRLNTKYKNQPTSFEIIFIHQDIRYEYGVVLTRERVHEEWLIAYPNERSQKWFSREYLAENKEYKWSFGKALKGEKQSIKKLVRSNSLFLSHAAQNNHIQLTQIFKWFDSELNILTSNTIVEGFTLRFCEEHDDFRQQVVNLLSEADIGISDIKIEQKPISEKEKSLFKQFLMRQVFENQELEEDINFEELQSLDVKTMHQMNDSEQEVEFEMEDESDGTQRLFQLAGLWLYVLQTGETLIVDELGRSLHPVLTRALIKMFNNPEINQNNAQIIFTIHDTTLLDTGLFRQDQVWFTEKEKSATKLYSLLDFMNLNDESLEKGYLLGLYGAVPFTDGLNSINYVKKR
>NC_019678.1|WP_044291587.1|1964785_1966495_+|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase-RibB/GTP-cyclohydrolase-II-RibA
METHSPQGGEPTPVTADSTQAFKFDSIDSALADLKTGRSVVVVDDENRENEGDLICAAQFATPDNINLMAVEARGLICLAMTGDRLDELDLPLMVKNITDTNQTAFTVSIDAGPELGVTTGISAEDRARTIQVALNPNTKPEDLRRPGHIFPIRAKKGGVLKRAGHTEAAVDLSRLAGLYPAGVICEIQNPDGSMARLPELIEYAKHHKMKIISIADLISYRLRYDRIIQRETVADLPTEFGNFKIYAYRHTLDNKEHVAIVKGDPEKFGDKPVMVRVHSECLTGDALGSLRCDCRMQLKAALKMIENAGEGVVVYLRQEGRGIGLINKLKAYSLQDMGLDTVEANERLGFPADLRDYGMGAQMLMDLNVHNIRLITNNPRKIAGLKGYGLEVVDRVPLLIEANDYNTHYLATKAKKLGHMLLQTYLVTLALHWQDEPLSITQRYERLEKIRNLAKDYHLLLQEETRPLGLALFSEPSLTVHLGLDQANVASADWYLEIGHPYVQAVTNILDKLVELPYVQKLEFLISPGVDPLSKLQVKLDRQAFEISQLPSSLSGELETQKIYSFGK
>NC_019678.1|WP_015117699.1|1963455_1964514_-|N-acetyl-gamma-glutamyl-phosphate-reductase
MGNFRRVPVGIIGASGYGGVQLVRLLLNHPELELVYLGGESSAGKDFSDIYPHLAQVVNLKVEALEPEAIARRCEVVFLSLPNGLACEIAPKLLEYGCKVLDLSADYRFRDLKTYSNWYGKKRQDIETVSNAIYGLPELYRDRISETQLVGCAGSYPTASLLGLSPLLKQGLIVPETAIIDGKGGTSTGGRQAETHLLLSEADNSLGAFNVARHRHTPEIEQICSDLAGHEVTVQFTHHLIPMVRGILATVYATLRDPGLVRDDLITIYKAFYRNSPWVKICEPGIYPQTKWTHGSNLCYMGIEVDSRTRRVIVISAIDNLIKGQSGQAIQCLNIMMGWDEMLGLPKLGFYP
>NC_019678.1|WP_157229394.1|1961674_1962964_+|phosphopyruvate-hydratase
MKHMMDTAIEAIVAREILDSRGRPTIEAEVHLVNGAMGLAQVPSGASTGTFEAHELRDGDKSRYGGKGVLKAVENVNETLAPKLLDMDALNQEHLDKTMIDIDGSKNKSNLGANAILGISLAAAKAGAESLGIPLYRYLGGPLANLLPVPLMNVINGGAHAANNVDFQEFMIVPIGASSFREALRWGAEVFATLSKVLDEKGVLTGVGDEGGFAPNLESNQVALELLVDAIKKAGYKPGEEVALALDVAASEFYKDGQYVYDGKPHSPAEFIDYMAQLVNQYPIVSIEDGLHEEDWQSWQLLTEKIGHHVQLVGDDLFVTNAERLQKGIEQKSANSILIKLNQIGSLTETLQTIDLATRNGFRSVISHRSGETEDTTIADLAVATRAGQIKTGSLCRSERVAKYNRLLRIEDELGDAAIYAGTVGLGPK
>NC_019678.1|WP_015117708.1|1975231_1975600_+|DUF559-domain-containing-protein
MTQLYNKKSEKEKRRKLRQDIVKAEKIIWDKIRNRQIEDCKFRRQYSVDKFVIDFYNPILKLAIEIDGESHFQEGAAEYDRERQSYIESLGIKFIRFTNNDVYNNLGGVLESIAMKVRELRG
>NC_019678.1|WP_015117709.1|1975680_1976232_-|hypothetical-protein
MNNFIQKIKLFYSQNYTEVYDEEELIDAKSLYPSQTWDFEVSGLENYSEEEAYLEECGYSLKTQFNLEDVHIFLNELQSGERKPTYPQTFAKSYLFYKQNVDEADFGSVYNFVVTIGRQRIFTTRVTTDGDDGWLEIFDAGGNNLGAASTNCNKIAWRSLDWIRKNFPAFPPEIDCKLRKRNQ
>NC_019678.1|WP_015117710.1|1976431_1977298_+|alpha/beta-hydrolase
MTTQKPKPLSKLKFIKRMLITIILIYLTFAIIIYSQVEKLIFLPPPSTYEDTEEIIKLISEDGTKLSAIHLSNPDAKYTILYAHGNGSDLGMIKPRLEQLKDIGFSVLGYDYRGYGTSEGKPSEKNAYKDIDTAYNYLTQELKILPQKIIPFGRSVGGGSAIDLAARKPVAGLITESTFTSIFKVKVPIKILPFDKFPNLEKIKRVKCPVLIMHGKLDEVVPFYHSEQLFEQTPSPKLSLWIEDAKHNNFPYAAGERYTKILKEFIELVNNYNSISYSPLLNKERGWG
>NC_019678.1|WP_015117711.1|1978557_1978797_+|hypothetical-protein
MTPKIMRQVWSVVEKTQTKTLLQMDDASLVKLLVKQTKNQASLEDCHEADVLCDYIQSRLPLIRDIAHERQYKLQSTFN
>NC_019678.1|WP_015117712.1|1978895_1980095_-|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD
MNDSPANPSADKLISNIEKEKVDEFELLYPKRSPVKAVGSDFDRTMMRRCLELARRGLGRTSPNPMVGAVIVKNGEIIGEGFHPRAGEPHAEVFALKAAGDNARGATIYVSLEPCNHHGRTPPCSEALVAAGVVKVVVGMVDPNPLVAGGGIQRLQEAGIEVVSGVEEEACRKLNEGFIHRILYKQPLGILKYAMTLDGKIATTTGHSAWVTNQDARTVVRQLRAGSDAVIVGGNTVRQDNPRLTSRLAGAHNPLRVVMSRTLDLPREAHLWQTQESPTLVLTELGAKPDLQENLRKQGVKVVELSPLTPEKAMAYLYDLGFCSVLWECGGILAANAIAQGAVQKVLAFIAPKIIGGSNAPTPVGDLGLTTMTQALSLERVEMRIVGSDCLVEGYLPCS
>NC_019678.1|WP_015117713.1|1980390_1981029_-|rod-shape-determining-protein-MreD
MKIPKFREKEKKRQTSGLPPSRRKKSKKQHIKPLSRWHPRLRQTTDWAVIAGSVLLCLFLLPNRFPGMELLGIGANWLLIWVVAWSVKRSALQGAFAGVILGLLQDAMTSPQPTHAVSLGVVGFLIGLFQKQRFIQEDFISIALIVFAMAILSDTIFALQLIGAGTASSDVIWAYYKKVTLASAILSSLWAPVVYYPLNRWWQQLKLAEQSS
>NC_019678.1|WP_015117714.1|1981052_1981841_-|rod-shape-determining-protein-MreC
MFTARRWWERFGLQFGLLALVVGGAVLIRQTQGEVLVEFYDGIARPLEVFQTQPNQQEYLKDAKVQELQARIVELESQNKNIKALLKYVEKEPKNTPTIPARVVGRSADNWWQQVTLNRGSLSGIKKGYIVKAEGGLVGLIDSVTPNTSRVLLISDMNSQVGVNISRTGAKGILRGDGSADAVLEFYEKVPNVKPGDVVSTSTYSSKFPSGVPIGKIKSLDLKRLPASVATIELFPPIRSLDWVTVNSKPTNPAPNNKDTQK
>NC_019678.1|WP_015117715.1|1982083_1983091_-|rod-shape-determining-protein
MGIDLGTANTLVYVSGKGIVLQEPSVVAIDQNEKVALAVGEDAKKMLGRTPGNVIALRPLRDGVIADFDTAELMLKNFIQRVNEGKSLVLPRIVIGIPSGVTGVERRAVMDAASQAGAREVYLIDEPVAAAIGAGLPVAEPTGNMIIDIGGGTTEVAVLSLQGTVLSESVRIAGDELTESIVQYMKKVHNLVIGERTAEDIKIRIGSAYPTHDDEEAMMEVRGLHLLSGLPRTVTIKGPEIRESMAEPLSVIIEAVKRTLERTPPELAADIIDRGIMLAGGGALLKGIDTLISHETGIVTHVAADPLSCVVLGTGRVLENFKQLERVFSARSRNI
>NC_019678.1|WP_015117716.1|1983459_1983819_+|single-stranded-DNA-binding-protein
MSINVVHLVGRVGTDPDMKYFESGSVKCRLTLAVDRRRKDSGPDWFNLELWGRTAEIANSYVRKGKQIAVKGSLKLDSWNDRSTGVPRSSPVINVDDLQLLGSRRDSEADMMNSSPEHF
>NC_019678.1|WP_015117717.1|1983985_1984732_-|DUF541-domain-containing-protein
MNKIKLSQSKHQNYQKFWRILPIALFFSVTSVQPGWAEEKVMLRTLTVTGQGTETIPTSLSKVSLGVQVQGKAANVVQQEAARKSNAVVALLKSRNVDKLQTTGIRLNPTYSYKDNVRKLQGYEATNTVSFRIPTDKAGKLLDETIKAGATRINSIRFVATEEEITQARQQALKEATQDAQKQANAVFSSLGFTAKEIVNIQVNNASMPEPVMYRRSAPTAAMAEAAPTPVIGGEQEVGASVTLRISY

Crispr_ID: NC_019678_7

• CRISPR_ID: NC_019678_7
• CRISPR_location: 2244490-2244639
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 3 spacers
• Cas_protein_info: csa3

Consensus repeat of NC_019678_7

Consensus_repeat	Method
CAAATGATGAAAAAGATG	CRT

spacers of NC_019678_7

>7.1|2244508|30|NC_019678|CRT
ACTCCCGAACAAATGCGTCAACACCAACAA
>7.2|2244556|18|NC_019678|CRT
ACTCCAGAACAAATGCAG
>7.3|2244592|30|NC_019678|CRT
ACTCCGGAACAAATACGTCAGCATCACCAA

CRISPR arrays and Neighbor proteins around NC_019678_7

CRISPR arrays

The CRISPR arrays of NC_019678_7

>merge|NC_019678|7|2244490-2244639|CRT
CAAATGATGAAAAAGATGACTCCCGAACAAATGCGTCAACACCAACAACAAATGATGAAAAAGATGACTCCAGAACAAATGCAGCAAATGATGAAAAAGATGACTCCGGAACAAATACGTCAGCATCACCAACAAATGATGGGAAATATG

>NC_019678|7|3|2244490-2244639|CRT
CAAATGATGAAAAAGATG	ACTCCCGAACAAATGCGTCAACACCAACAA
CAAATGATGAAAAAGATG	ACTCCAGAACAAATGCAG
CAAATGATGAAAAAGATG	ACTCCGGAACAAATACGTCAGCATCACCAA
CAAATGATGGGAAATATG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015117908.1|2233000_2233651_-|arsenical-resistance-protein-ArsH	unknown	unknown	gnl|CDD|274260
NC_019678.1|WP_015117929.1|2252968_2253493_+|hypothetical-protein	unknown	unknown	gnl|CDD|226980
NC_019678.1|WP_015117923.1|2246227_2246680_+|DUF305-domain-containing-protein	unknown	unknown	gnl|CDD|367619
NC_019678.1|WP_015117927.1|2250368_2250563_+|heavy-metal-associated-domain-containing-protein	unknown	unknown	gnl|CDD|225328
NC_019678.1|WP_015117911.1|2236109_2236430_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NC_019678.1|WP_015117922.1|2245769_2246108_+|four-helix-bundle-copper-binding-protein	unknown	unknown	gnl|CDD|153434
NC_019678.1|WP_015117915.1|2239512_2239908_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_157229265.1|2249382_2250264_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|223669
NC_019678.1|WP_015117930.1|2253677_2253941_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015117913.1|2238536_2239019_-|DUF2808-domain-containing-protein	unknown	unknown	gnl|CDD|371328
NC_019678.1|WP_044291625.1|2242528_2243443_+|copper-resistance-protein-B	unknown	unknown	gnl|CDD|377498
NC_019678.1|WP_015117924.1|2246786_2248853_+|copper-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319850
NC_019678.1|WP_015117919.1|2244766_2245249_+|hypothetical-protein	unknown	unknown	gnl|CDD|350353
NC_019678.1|WP_015117914.1|2239134_2239440_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015117928.1|2250641_2252954_+|copper-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319783
NC_019678.1|WP_015117916.1|2240378_2242235_+|copper-resistance-system-multicopper-oxidase	unknown	unknown	gnl|CDD|273649
NC_019678.1|WP_015117910.1|2234946_2235993_-|PstS-family-phosphate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270372
NC_019678.1|WP_015117909.1|2233733_2234915_-|ACR3-family-arsenite-efflux-transporter	unknown	unknown	gnl|CDD|213563
NC_019678.1|WP_015117925.1|2249032_2249371_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_044290827.1|2237130_2238123_-|RpoD/SigA-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274382

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019678.1|WP_015117911.1|2236109_2236430_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	2.6e-23	77.4	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_157229265.1|2249382_2250264_+|alpha/beta-fold-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.49587e-23
NC_019678.1|WP_015117911.1|2236109_2236430_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	4.73095e-22
NC_019678.1|WP_015117922.1|2245769_2246108_+|four-helix-bundle-copper-binding-protein	gnl|CDD|153434	cd08026, DUF326, Cysteine-rich 4 helical bundle widely conserved in bacteria. This functionally uncharacterized protein forms a 4-helical bundle with a bromodomain-like topology. It is present in major bacterial lineages and contains highly conserved cysteines in a repeated pattern, whose sidechains appear buried. Some family members have been (mis)annotated as putative ferredoxins.	7.85324e-22
NC_019678.1|WP_015117908.1|2233000_2233651_-|arsenical-resistance-protein-ArsH	gnl|CDD|274260	TIGR02690, arsenical_resistance_protein_ArsH_putative, arsenical resistance protein ArsH. Members of this protein family occur in arsenate resistance operons that include at least two different types of arsenate reductase. ArsH is not required for arsenate resistance in some systems. This family belongs to the larger family of NADPH-dependent FMN reductases (pfam03358). The function of ArsH is not known. [Cellular processes, Detoxification].	2.43947e-110
NC_019678.1|WP_015117909.1|2233733_2234915_-|ACR3-family-arsenite-efflux-transporter	gnl|CDD|213563	TIGR00832, Uncharacterized_transporter_slr0944, arsenical-resistance protein. The Arsenical Resistance-3 (ACR3) Family (TC 2.A.59) The first protein of the ACR3 family functionally characterized was the ACR3 protein of Saccharomyces cerevisiae. It is present in the yeast plasma membrane and pumps arsenite out of the cell in response to the pmf. Similar proteins are found in bacteria, often as part of a four gene operon with an regulatory protein ArsR, a protein of unknown function ArsH, and an arsenate reductase that converts arsenate to arsenite to facilitate transport. [Cellular processes, Detoxification, Transport and binding proteins, Anions].	4.0199e-137
NC_019678.1|WP_015117913.1|2238536_2239019_-|DUF2808-domain-containing-protein	gnl|CDD|371328	pfam10989, DUF2808, Protein of unknown function (DUF2808). This family of proteins with unknown function appears to be restricted to Cyanobacteria.	1.60394e-06
NC_019678.1|WP_044291625.1|2242528_2243443_+|copper-resistance-protein-B	gnl|CDD|377498	pfam05275, CopB, Copper resistance protein B precursor (CopB). This family consists of several bacterial copper resistance proteins. Copper is essential and serves as cofactor for more than 30 enzymes yet a surplus of copper is toxic and leads to radical formation and oxidation of biomolecules. Therefore, copper homeostasis is a key requisite for every organism. CopB serves to extrude copper when it approaches toxic levels.	1.06435e-116
NC_019678.1|WP_015117924.1|2246786_2248853_+|copper-translocating-P-type-ATPase	gnl|CDD|319850	cd07552, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to Archaeoglobus fulgidus CopB, a Cu(2+)-ATPase. Archaeoglobus fulgidus CopB transports Cu(2+) from the cytoplasm to the exterior of the cell using ATP as energy source, it transports preferentially Cu(2+) over Cu(+), it is activated by Cu(2+) with high affinity and partially by Cu(+) and Ag(+). This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_019678.1|WP_015117919.1|2244766_2245249_+|hypothetical-protein	gnl|CDD|350353	cd14503, PTP-bact, bacterial tyrosine-protein phosphataseS similar to Neisseria NMA1982. This subfamily is composed of bacterial tyrosine-protein phosphatases similar to Neisseria meningitidis NMA1982, which displays phosphatase activity but whose biological function is still unknown.	1.80731e-35
NC_019678.1|WP_015117927.1|2250368_2250563_+|heavy-metal-associated-domain-containing-protein	gnl|CDD|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	3.93831e-10
NC_019678.1|WP_015117928.1|2250641_2252954_+|copper-translocating-P-type-ATPase	gnl|CDD|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_019678.1|WP_015117923.1|2246227_2246680_+|DUF305-domain-containing-protein	gnl|CDD|367619	pfam03713, DUF305, Domain of unknown function (DUF305). Domain found in small family of bacterial secreted proteins with no known function. Also found in Paramecium bursaria chlorella virus 1. This domain is short and found in one or two copies. The domain has a conserved HH motif that may be functionally important. This domain belongs to the ferritin superfamily. It contains two sequence similar repeats each of which is composed of two alpha helices.	1.56809e-07
NC_019678.1|WP_015117910.1|2234946_2235993_-|PstS-family-phosphate-ABC-transporter-substrate-binding-protein	gnl|CDD|270372	cd13654, PBP2_phosphate_like_2, Substrate binding domain of putative ABC-type phosphate transporter, a member of the type 2 periplasmic binding fold superfamily. This subfamily contains uncharacterized phosphate binding domains found in PstS proteins that serve as initial receptors in the ABC transport of phosphate in eubacteria and archaea. After binding the ligand, PstS interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The PstS proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	8.18059e-133
NC_019678.1|WP_015117916.1|2240378_2242235_+|copper-resistance-system-multicopper-oxidase	gnl|CDD|273649	TIGR01480, unnamed_protein_product, copper-resistance protein, CopA family. This model represents the CopA copper resistance protein family. CopA is related to laccase (benzenediol:oxygen oxidoreductase) and L-ascorbate oxidase, both copper-containing enzymes. Most members have a typical TAT (twin-arginine translocation) signal sequence with an Arg-Arg pair. Twin-arginine translocation is observed for a large number of periplasmic proteins that cross the inner membrane with metal-containing cofactors already bound. The combination of copper-binding sites and TAT translocation motif suggests a mechansism of resistance by packaging and export. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds].	0
NC_019678.1|WP_015117929.1|2252968_2253493_+|hypothetical-protein	gnl|CDD|226980	COG4633, COG4633, Plastocyanin domain containing protein [General function prediction only].	3.60096e-57
NC_019678.1|WP_044290827.1|2237130_2238123_-|RpoD/SigA-family-RNA-polymerase-sigma-factor	gnl|CDD|274382	TIGR02997, RNA_polymerase_sigma_subunit_sigma70/sigma32, RNA polymerase sigma factor, cyanobacterial RpoD-like family. This family includes a number of closely related sigma-70 (TIGR02937) factors in the cyanobacteria. All appear most closely related to the essential sigma-70 factor RpoD, and some score above trusted to the RpoD C-terminal domain model (TIGR02393).	1.00819e-156

Protein sequences

>NC_019678.1|WP_044291625.1|2242528_2243443_+|copper-resistance-protein-B
MINEKEWPEPLDDSQKLKTELNIETIDFKKENTGKPQEQKKTKFRQSILTDESILPTVEIANQKQWRLSQKQNNISQVTNEEDWPEPVDDNQIFWLLLVDQLEFRDNDGEATFNWDAQGWIGGDYKRLWIKTEGDIGLETADGEAELQLLYGKLIAPFWDLQVGLRYDQLYSSDGGPGRAFGVIGVQGLAPYLFEVDAALFVSQDGDVSARLQAEYQLLLSQRLILQPEFETNIAIQQVEDFGVGSGINDIELGLRLRYEISRKFAPYVGASWTRKLGNTADLAREEGESVDNFTLLGGVRLLF
>NC_019678.1|WP_015117916.1|2240378_2242235_+|copper-resistance-system-multicopper-oxidase
MNYKTNALTRRNFLRFTTGIGIAVGLDSLVPAYARQVVANETGKGRNYPDVIDLKVQETAVKIGNKQAKALTVNGSVPGALIRLREGQNVTINVTNELKKDTSIHWHGILLRPNMDGVPGVSFAGIKPGQTFTYRFPVAQNGTYWYHSHSGLQEQRGHYGALIIDPIEPEPFEYDQDYVVMLSDWTFDNPHDILANLKKMPAYYNYQRRTIADLSKDLAWRRMRMDPADIADVTGATYTYLMNGLVPDSNWTGLFQAGNKVRLRFINGSAMTFFDVRIPGLKMTVVQADGQNVQPVSVDEFRIGVAETYDVIVEPQDEQAYTIFAETMDRSGYARGTLAVHEGLRAPLPERRERPLRTMADMGMAHDMSGMNGDSSMKDMPGMNNNSSMNHDMSGMNSNSSMKDMPGMNDNSSMNHDMSGMNGDDSSMKDMPGMNHDMSKNDAGVPHGPDDHGLGNATVPMMVKSRLHEPGVGLENTGHRVLVYTDLRSLKPGYDKRKPERELELHLTGIMERYMWSFDGKKYSEDKEITFYNGERLRLIFVNDTMMEHPIHLHGMWMELDNGAGEYKPRKHTINVKPAERLPVEINVDAPGKWAFHCHLLYHMKVGMFRTVAVVNRG
>NC_019678.1|WP_015117915.1|2239512_2239908_-|hypothetical-protein
MKSQIRQIIFIGSTLVATTLVQASPLKAHEKKFHGAKKTSEPKTEVIVTPEAKTQPESSNSSRMLNMKNPETSVKPSSTPMKMHAEKKGINSVNSSTINNSSLIPQPGEMVFSLLLLGTFLLYYTKRRMYQ
>NC_019678.1|WP_015117914.1|2239134_2239440_-|hypothetical-protein
MALNKARIRQLHSLFAPIMLLPAILSLITGSLFHIAVISGKTEEFLWLLEWHRGKFGRINLEMIYPFLNAFGLLMLAVTGIIMWFQTRRRNTKSKTSNISS
>NC_019678.1|WP_015117913.1|2238536_2239019_-|DUF2808-domain-containing-protein
MKKILFYTAATFTLAVSIGTAIAQPTTAATNFARITNFSEFPKGIRHWSILRHTLKIAISEQSNAVSKIIIEAPNNIVLRDNIDVSNQSGEKINASVAIDEKKAVLTFSEPVPPGTKLTIEMNKVRKLRATRGEMLYKVFVNFVDSKQTVPVGIARLRVS
>NC_019678.1|WP_044290827.1|2237130_2238123_-|RpoD/SigA-family-RNA-polymerase-sigma-factor
MSNPISQPNKDSKKTCKSSKDTVGSYFQDIICIPLLTSEEEINLAKKVQQRMSLLAIKEELSKKLQRQPTLQEWSDKAQLNDTELLEQIDRGQRAKQKMIAANLRLVVTIAKKYQKRNLDFLDLIQEGTLGLERAVDKFQPALGYKFSTYAYWWIRQGITRAISQQSRTIRLPIHITEKLNKIKRVQRELSQKLGRNPSVTEIAEVMEVKPSQIRDYLSLARKPMSLDVRVGEEQNTDLKDLLEDNSFSPEDYVLKESLNQTIKDLLSKLSPQQQEILTLRYGLEDGQELTLNQVSQRMGISRQRVLQLQRQALAFLQRYGKKSRIFLNN
>NC_019678.1|WP_015117911.1|2236109_2236430_-|winged-helix-turn-helix-transcriptional-regulator
MQVTHTNDIIIAGFHALSEPLRIQVLQLLKKQEMCVCDLCDILEVSQSKLSFHLKNLKEAKLVYARQEGRWIYYSLNSAQFEVLEDYLAQYRLINQVLPAPACKDS
>NC_019678.1|WP_015117910.1|2234946_2235993_-|PstS-family-phosphate-ABC-transporter-substrate-binding-protein
MKATATKMALMLGVLVLTASCTNTSNTPSTTVSQGKVSEVSNSETTIKIDGSSTVYPITQAVTKEFQQQNQAEVKVDVSGTTGGFERFCKGETDISNASRPILKQELKTCTANGVIFTELPIAFDALTVAVNPQNTWAKEITVAELKKIWEPSAQGKITNWKQVRASFPDKPLSLYGAGDKSGTYDYFTKAVVGESGDSRSDYTASEDDEVLVSGVSKDSNALGYFGYAYYEQNQDKLKALGIDNGKGAVLPSRETVEKAEYQPLSRPLFIYVNIKSAQKKAGVRDFVNFYIEKAPTTVSSVGYVPLPEDAYSLDKLHFTRGKAGTVFEGQARLDLTIDEVLRKRAEF
>NC_019678.1|WP_015117909.1|2233733_2234915_-|ACR3-family-arsenite-efflux-transporter
MSTNNSQANKAPVKAGSNLSFFEKYLTVWVFFCIIAGIALGRTFPGIATALDAMSVFQVSIPIAVCLFFMMYPIMVKIDFSQAVHAIRAPKPVILTLVINWLIKPFTMVAFAQFFLGWLFRPLIEGSEIIRGSEVALSNSYIAGAILLGIAPCTAMVLMWGYLSYSNQGHTLVMVAVNSLAMLFLYAPLGRWLLAANNLSVPWQTIVLSVLIYVGLPLIAGIFSRYWIMKNKGREWFERRFLKYLTPISITALLLTLVLLFAFKGELIVENPLHILLIAVPLFIQTNFIFLIAYVAALKLNLSYEDAAPAALIGASNHFEVAIATAVMLFGLNSGAALATVVGVLIEVPLMLMLVEFCKRTAAWFPREPEKATLRDPRPALMIRMNNDDSSLK
>NC_019678.1|WP_015117908.1|2233000_2233651_-|arsenical-resistance-protein-ArsH
MTDFNHPPRILFLYGSLRERSYSRLAAEEAARIIAGFGAEVKFFHPHDLPIRGSVPESYAKVQELRELTQWSEGQVWSSPEMHGNLTGILKNQIDWIPLSIGAVRPTQGRTLAVMQVNGGSQSFNAVNSMRLLGRWMRMFTIPNQSSVAKAYQEFNEDGTMKDSPYRDRIIDVMEELYKFTLLLRSEADYLTNRYSERKQEAIKAGISVDNCLPKF
>NC_019678.1|WP_015117919.1|2244766_2245249_+|hypothetical-protein
MENTKKINDDITVTGQVTPEQLQQAAKSGLKSVLNLRAPDEKGFMKDEQQQAEAAGLNYTNIPLKVETIDDKLIDEILEQIDQLPKPALIHCASGMRAGAMALMNLAIDKGMTPKEAFETAEKLGFDCSSSPKLKQVFEEYVAKHSPPTYGDSDIKCIPK
>NC_019678.1|WP_015117922.1|2245769_2246108_+|four-helix-bundle-copper-binding-protein
MLLVHEEYQSSFDVAMRCVVECEHCAEACMGMSEMVQCARSCLDCAEICRTAATYMVRGSRYISHLARACAEICEACATECEKHDAEHCKKCAKACRDSVEEYKKIAAVAAR
>NC_019678.1|WP_015117923.1|2246227_2246680_+|DUF305-domain-containing-protein
MESKSKNNSYISLLIALIISYVVMLVLMLSRVNEFGNFFISLNQVYMSGLMVSTMLLIMLFAMGSMYKNKKLNIALLIGGTASILLFWTLVRTQAAVGNQQFLRSMIPHHAAAILVCQQASLTDARIQELCTEIVQTQKEEIRIMKELMK
>NC_019678.1|WP_015117924.1|2246786_2248853_+|copper-translocating-P-type-ATPase
MAKQHHSRNNHAVREREERQNHSEQAGHLEHGVHAGHGKHAGHSPEIFKRRFFICLVLTLPILYFSTQLQTWLNYQAITFPGSEWINPILGIIIYFYGGWVFLKGAWNELHSKIGMMTLIALAITVAFVYSLAVSFGLQGKPFYWELATLVDIMLLGHWVEMASVQGASRALENLAQLVPSTAHRLINGRVEDVRVSEIRAEDVILIRPGEQVPNDGIVIEGNTNINESFLTGESRPVSKHEGDEVVAGSVNGEGSVKVEVSRIGGDTTISQIMRLVEEAQGSRSRYQALADKTAYWLTIVAITVGSITFFVWLGLSDLVFAVNRTVTVLVITCPHALGLAIPLVIANSTALAAKNGILVRNRDSLERAKDIKNMAFDKTGTLTEGKFGVQRMYTEGLDDNEALAIAAALETSSEHPLAKAVVQAAERRELDLPQMTNFNTVTGHGVEGKVNGKKYRIGRPEWVEEDNLTFPSSLRQGLQIVNERGESPVVLMTEESAVAVISMADQVRERARETVNQLQAKGIQVVMITGDAEAVARTVAEDLGIERYYARVLPEDKVSIIKQLKQEGPTAFVGDGINDAAALLEANIGIAIGAGTNVAIESADLVLIEDDPLDAVKALNLAQKTYSKMIQNLFWATGYNVIAIPLAAGVLYAWGFLLSPAIGALLMSLSTVIVAINAVMLRRAKLA
>NC_019678.1|WP_015117925.1|2249032_2249371_+|hypothetical-protein
MNAYDNFNQLRLSETVSPKTSLVEAPKNDKNPSNNDTIAGMGFLLFLTLMIALIKWCDIRKASQEDFSKIPINHKTPCSKCRYFNNNSYIKCAVQPEKVMTKEAKDCQDYCP
>NC_019678.1|WP_157229265.1|2249382_2250264_+|alpha/beta-fold-hydrolase
MISKSNKSNQTLQLKDGRQMGYAEFGDLNGKPVLFFHGTPGSRLTRYPDESIATLLGVRIINIDRPGYGLSDFVPDNTLVNWTEDIIELADALKIEQFAVTGVSGGGAYALACTSEIPERITRAGVISSISPFDVSHVTEGMNLINRVLFGVGQYAPFLLNPLLSPIVRTARKEPQKLFDYGLTNYFPIPDKEVLFQPMVREMFLEDLPQAFLQGACGFTLDMKILVQSWGFQLNNISRKVYLWHGEKDENVPPNAGRYLANMIPNCEARFYPDEGHLLIFNHWQEILTTLVS
>NC_019678.1|WP_015117927.1|2250368_2250563_+|heavy-metal-associated-domain-containing-protein
MTIQLKVPDIACSACVNTVTKAIKSVDANATVEADTKTKIVNVQSQHSVDKIKEIIAEAGYPAA
>NC_019678.1|WP_015117928.1|2250641_2252954_+|copper-translocating-P-type-ATPase
MDTTTLKLRGMSCASCANSIEETINSVPGVSECNVNFGAEQATVKYNPQKTDIKKIQDAVDAAGYSATPLQEQEMITGEDDEDKAARKAESRDLIRKLIVGGAISIILIFGSLPMMTGLELPFVPAWLHNAWLQLAFTAPVQFWCGYGFYTGAWKAFKRHGATMDTLIALGTSAAFFYSLFATIFPDFFLNQGLMPEVYYETAAVVITLILLGQLFENRAKGQTSEAIRKLIGLQARDARVIRNGREVDVPIQEVELDDIILVRPGEKIPVDGEVVHGTSTIDEAMVTGESLPVKKQPGDEVIGATINKTGSFKFKATRVGKDTVLSQIVQLVRQAQGSKAPIQRLADQVTGWFVPVVIAIAISTFVIWFDFMGNISLALITTVGVLIIACPCALGLATPTSVMVGTGKGAENGILIKGAESLELAHKIKTIVLDKTGTLTEGKPTVTNFVTVRGTANQNEFKLIKLAAELERNSEHPLAEAVVRYAESQGVELLDASDFEAVAGSGVQGYVADNFVQIGTKRWLSEIGIDTNLFGEQKDDWESLGQTVIWIAVDGKVEGLMGIADTLKATSTEAVRVMRKMGLEVVMLTGDNRPTAEAIAGEVGIDRVFAEVRPDQKAAVVKSLQAEGIKKRGTNKSSQNETKASVAKIVAMVGDGINDAPALAQADVGMAIGTGTDVAIAASDITLISGDLRSIVTAIKLSRATINNIRQNLFFAFFYNVLGIPIAAGILFPIFGWLLNPIIAGGAMAFSSVSVVTNALRLRNFQLKG
>NC_019678.1|WP_015117929.1|2252968_2253493_+|hypothetical-protein
MLNKKKILANLAGVGFFLSVVSGTALAQKPVSMPVSEQENVQFRRIEQPLGLKAAVTVGGIGLIGLELWWFLFSKSKTVQANRNQDIQEITITVDGGYEPNQVVVEAGQLVRLNFFRRDASSCLEKVLVPDFHIAQDLTLNQVTTVEFTPEKPGEYTFSCGMNMYRGKILAQLN
>NC_019678.1|WP_015117930.1|2253677_2253941_-|hypothetical-protein
MISMYRSFIPDASNQEKVIPNSQPIISQVPEPEKIRHTLIGSSEAVMGTIQVLHQLGYANIGDWSPLLPTNNRGEVMSVLIRSVTGK

Crispr_ID: NC_019678_8

• CRISPR_ID: NC_019678_8
• CRISPR_location: 2760060-2760199
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 1 spacers

Consensus repeat of NC_019678_8

Consensus_repeat	Method
CCAGAGATTGAAAACCTCTGTCTCATAGCTAAAATCATCTAAAGATG	CRISPRCasFinder

spacers of NC_019678_8

>8.1|2760107|46|NC_019678|CRISPRCasFinder
GTTGGGAAAATTGCACATCAAAACAAAAAATAAACCCATTTATTCA

CRISPR arrays and Neighbor proteins around NC_019678_8

CRISPR arrays

The CRISPR arrays of NC_019678_8

>merge|NC_019678|8|2760060-2760199|CRISPRCasFinder
CCAGAGATTGAAAACCTCTGTCTCATAGCTAAAATCATCTAAAGATGGTTGGGAAAATTGCACATCAAAACAAAAAATAAACCCATTTATTCACCAGAGGTTGAAAACCTCTGTCTCATAGCTAAAATCATCTAAAGATG

>NC_019678|8|7|2760060-2760199|CRISPRCasFinder
CCAGAGATTGAAAACCTCTGTCTCATAGCTAAAATCATCTAAAGATG	GTTGGGAAAATTGCACATCAAAACAAAAAATAAACCCATTTATTCA
CCAGAGGTTGAAAACCTCTGTCTCATAGCTAAAATCATCTAAAGATG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015118334.1|2772442_2773267_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187576
NC_019678.1|WP_015118323.1|2751107_2751752_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NC_019678.1|WP_015118324.1|2752219_2753014_-|hypothetical-protein	unknown	unknown	gnl|CDD|197230
NC_019678.1|WP_015118319.1|2745678_2746119_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015118333.1|2771853_2772339_+|glutathione-peroxidase	unknown	unknown	gnl|CDD|238207
NC_019678.1|WP_015118337.1|2775514_2776531_-|DUF3445-domain-containing-protein	unknown	unknown	gnl|CDD|378763
NC_019678.1|WP_015118322.1|2750237_2750873_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015118328.1|2759587_2759992_-|IS200/IS605-family-transposase	unknown	unknown	gnl|CDD|376616
NC_019678.1|WP_015118325.1|2753019_2754882_-|DUF1998-domain-containing-protein	unknown	unknown	gnl|CDD|378167
NC_019678.1|WP_015118336.1|2774352_2775351_+|hypothetical-protein	unknown	unknown	gnl|CDD|197318
NC_019678.1|WP_015118330.1|2767676_2769575_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl|CDD|234729
NC_019678.1|WP_015118329.1|2763649_2766871_-|DNA/RNA-helicase	unknown	unknown	gnl|CDD|350769
NC_019678.1|WP_015118326.1|2755293_2758821_-|helicase-with-metal-binding-cysteine-cluster	unknown	unknown	gnl|CDD|197757
NC_019678.1|WP_015118335.1|2773315_2774239_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NC_019678.1|WP_015118331.1|2769852_2770098_-|photosystem-I-iron-sulfur-center-protein-PsaC	unknown	unknown	gnl|CDD|177005
NC_019678.1|WP_015118338.1|2776567_2779159_-|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|376570
NC_019678.1|WP_015118332.1|2770534_2771326_+|DnaJ-domain-containing-protein	unknown	unknown	gnl|CDD|224276
NC_019678.1|WP_015118327.1|2759072_2759333_+|HigA-family-addiction-module-antidote-protein	unknown	unknown	gnl|CDD|225635
NC_019678.1|WP_015118320.1|2746500_2747355_-|DUF72-domain-containing-protein	unknown	unknown	gnl|CDD|376655
NC_019678.1|WP_044290869.1|2747487_2749632_-|hypothetical-protein	unknown	unknown	gnl|CDD|369942

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015118334.1|2772442_2773267_+|SDR-family-oxidoreductase	gnl|CDD|187576	cd05266, SDR_a4, atypical (a) SDRs, subgroup 4. Atypical SDRs in this subgroup are poorly defined, one member is identified as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is related to, but is different from, the archetypical SDRs, GXGXXG. This subgroup also lacks most of the characteristic active site residues of the SDRs; however, the upstream Ser is present at the usual place, and some potential catalytic residues are present in place of the usual YXXXK active site motif. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.23372e-62
NC_019678.1|WP_015118323.1|2751107_2751752_+|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	4.98043e-14
NC_019678.1|WP_015118324.1|2752219_2753014_-|hypothetical-protein	gnl|CDD|197230	cd09132, PLDc_unchar4, Putative catalytic domain of uncharacterized phospholipase D-like proteins. Putative catalytic domain of uncharacterized phospholipase D (PLD, EC 3.1.4.4)-like proteins. Members of this subfamily contain one copy of HKD motif (H-x-K-x(4)-D, where x represents any amino acid residue) that characterizes the PLD superfamily.	4.75344e-27
NC_019678.1|WP_015118333.1|2771853_2772339_+|glutathione-peroxidase	gnl|CDD|238207	cd00340, GSH_Peroxidase, Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per subunit, which is involved in catalysis. Different isoenzymes are known in mammals,which are involved in protection against reactive oxygen species, redox regulation of many metabolic processes, peroxinitrite scavenging, and modulation of inflammatory processes.	2.86733e-75
NC_019678.1|WP_015118337.1|2775514_2776531_-|DUF3445-domain-containing-protein	gnl|CDD|378763	pfam11927, DUF3445, Protein of unknown function (DUF3445). This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 264 to 418 amino acids in length. This protein has a conserved RLP sequence motif. This protein has two completely conserved R residues that may be functionally important.	6.03416e-49
NC_019678.1|WP_015118335.1|2773315_2774239_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.89063e-12
NC_019678.1|WP_015118328.1|2759587_2759992_-|IS200/IS605-family-transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	4.24635e-32
NC_019678.1|WP_015118325.1|2753019_2754882_-|DUF1998-domain-containing-protein	gnl|CDD|378167	pfam09369, DUF1998, Domain of unknown function (DUF1998). This family of proteins are functionally uncharacterized. They are mainly found in helicase proteins so could be RNA binding. This family includes a probable zinc binding motif at its C-terminus.	1.18181e-12
NC_019678.1|WP_015118336.1|2774352_2775351_+|hypothetical-protein	gnl|CDD|197318	cd09084, EEP-2, Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; uncharacterized family 2. This family of uncharacterized proteins belongs to a superfamily that includes the catalytic domain (exonuclease/endonuclease/phosphatase, EEP, domain) of a diverse set of proteins including the ExoIII family of apurinic/apyrimidinic (AP) endonucleases, inositol polyphosphate 5-phosphatases (INPP5), neutral sphingomyelinases (nSMases), deadenylases (such as the vertebrate circadian-clock regulated nocturnin), bacterial cytolethal distending toxin B (CdtB), deoxyribonuclease 1 (DNase1), the endonuclease domain of the non-LTR retrotransposon LINE-1, and related domains. These diverse enzymes share a common catalytic mechanism of cleaving phosphodiester bonds; their substrates range from nucleic acids to phospholipids and perhaps, proteins.	2.68698e-14
NC_019678.1|WP_015118330.1|2767676_2769575_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl|CDD|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NC_019678.1|WP_015118329.1|2763649_2766871_-|DNA/RNA-helicase	gnl|CDD|350769	cd18011, DEXDc_RapA, DEXH-box helicase domain of RapA. In bacteria, RapA is an RNA polymerase (RNAP)-associated SWI2/SNF2 (switch/sucrose non-fermentable) protein that mediates RNAP recycling during transcription. The ATPase activity of RapA is stimulated by its interaction with RNAP and inhibited by its N-terminal domain. The conformational changes of RapA and its interaction with RNAP are essential for RNAP recycling. RapA is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	2.28469e-57
NC_019678.1|WP_015118326.1|2755293_2758821_-|helicase-with-metal-binding-cysteine-cluster	gnl|CDD|197757	smart00490, HELICc, helicase superfamily c-terminal domain.	6.86208e-09
NC_019678.1|WP_015118331.1|2769852_2770098_-|photosystem-I-iron-sulfur-center-protein-PsaC	gnl|CDD|177005	CHL00065, psaC, photosystem I subunit VII.	9.42204e-53
NC_019678.1|WP_015118338.1|2776567_2779159_-|GAF-domain-containing-protein	gnl|CDD|376570	pfam01590, GAF, GAF domain. This domain is present in cGMP-specific phosphodiesterases, adenylyl and guanylyl cyclases, phytochromes, FhlA and NifA. Adenylyl and guanylyl cyclases catalyze ATP and GTP to the second messengers cAMP and cGMP, respectively, these products up-regulating catalytic activity by binding to the regulatory GAF domain(s). The opposite hydrolysis reaction is catalyzed by phosphodiesterase. cGMP-dependent 3',5'-cyclic phosphodiesterase catalyzes the conversion of guanosine 3',5'-cyclic phosphate to guanosine 5'-phosphate. Here too, cGMP regulates catalytic activity by GAF-domain binding. Phytochromes are regulatory photoreceptors in plants and bacteria which exist in two thermally-stable states that are reversibly inter-convertible by light: the Pr state absorbs maximally in the red region of the spectrum, while the Pfr state absorbs maximally in the far-red region. This domain is also found in FhlA (formate hydrogen lyase transcriptional activator) and NifA, a transcriptional activator which is required for activation of most Nif operons which are directly involved in nitrogen fixation. NifA interacts with sigma-54.	3.76567e-21
NC_019678.1|WP_015118332.1|2770534_2771326_+|DnaJ-domain-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.00439e-31
NC_019678.1|WP_015118327.1|2759072_2759333_+|HigA-family-addiction-module-antidote-protein	gnl|CDD|225635	COG3093, VapI, Plasmid maintenance system antidote protein [General function prediction only].	2.03644e-19
NC_019678.1|WP_015118320.1|2746500_2747355_-|DUF72-domain-containing-protein	gnl|CDD|376655	pfam01904, DUF72, Protein of unknown function DUF72. The function of this family is unknown.	3.31519e-72
NC_019678.1|WP_044290869.1|2747487_2749632_-|hypothetical-protein	gnl|CDD|369942	pfam08548, Peptidase_M10_C, Peptidase M10 serralysin C terminal. Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.	5.51399e-09

Protein sequences

>NC_019678.1|WP_015118328.1|2759587_2759992_-|IS200/IS605-family-transposase
MSLWRIYYHIIWTTKQRQPLISADKEPELYNYIIGKSDFLNCIIHAIGGMEDHIHVIVSIPPTIAISEYVKKVKGSSSYHINHNTPTTSDKFSWQEGYGVFSLGSKQLEKAVIYVKNQKIHHSQGTTNSYLENV
>NC_019678.1|WP_015118327.1|2759072_2759333_+|HigA-family-addiction-module-antidote-protein
MTQNLTSARAISPGKVLHRELQARGWTQKYLAEIMGCGVKNINEIIQEAKEVTPEIAIELSQVLGTSAEFWTNLETKYQLHLSGKE
>NC_019678.1|WP_015118326.1|2755293_2758821_-|helicase-with-metal-binding-cysteine-cluster
MTAAIPNQVQSNQSSTVRAHLIEALQLDLIGPTPDDINYAEEILDQAPSKGYLTGFLVPYGASIEQRTDDNGDDELDQVSGGAAGEDENVPEKTFAKKAFFPSSIGLSLLVNQNTSHLNVTVAWGDYYPYKENIDTDTENKTIPQEEQLEATDEKQTQTIPGCWKRIPRQQEITIPIGEHNPKQLELPLNKGGVSPNLNIPIPDSNGLELVVSVRPVASKELVPAGSLSVSVFLVNKRVPTNDKERDTTYTFQTSLAIRTIEPFVPRPNLRGRDNDDWDESVADLQYRDNYEYAVGHNVSAVAVTNVDGNCNYVRTAWIPTADVEKVIATEDEFKDVELGMEELAKAQTPEALQNMLSPMVNAYGDWIEQQRLTSPQEPKRFNIASDLLNRAEIAKNRINAGIQALTDPDIFTAFQIGNRAIATYIRQRKTHGQNITPESIAPPKWRPFQLAFILMNLLGVANPEHNERELVDLLFFPTGGGKTEAYLGLAAFTLVLRRLHNPDPKTKIKSAGLSVLMRYTLRLLTLDQLGRAAAMICALELEREKNPELLGTWSFEIGLWVGQAATPNRMGKKGDNDDYSARKRTLDFQKNNRNPSPIPLENCPWCGTKFDRNSFQLHPNPDQPSNLHVYCSNRRCDFSGRKGKNLPIVTVDEPIYRRLPCFIIATVDKFASLPWVGETGALFGKVDRYDQNGFYGPTQPGRGKALGSHLPPPDLIIQDELHLISGPLGTMVGLYETAIDALCSREINGKPTRPKIVASTATVRRASKQIQALFGRSEVDIFPPPGPDRRDSFFAKTVPASEKNARTYVGIAAQGRSAKVVLLRTYLALLGAAQKHWLAAGGKKNPDNPADPYMTLLGYFNSLRELGGSRRIVEDEVKTRLNRYSQRKRIGEASGLFADRKIDDEPEELTSRVSTSEVANTKQRLESTFDKNDKVDVVLATNMISVGLDITRLGLMVVLGQPKTAAEYIQATSRVGRDEKRPGLVVTLLNIHRPRDRSHYERFCAWHSSFYRAVEATSVTPFSPRAIDRGIAAITVALARLGHTKMTAPTNAIEILQNRQELEFVVDKIAQRAEMHDKELSASDSEALRQKVRNTVKDLLDLWERIANDKINLQYQREVGEAPPLIFEPLDPELLNQPLEARKFKAQRSLRDVEPTVNLWVINPNGDEVEEVKK
>NC_019678.1|WP_015118325.1|2753019_2754882_-|DUF1998-domain-containing-protein
MSKSNKKIPPAGQIRQSQILSTFGSGSMVDLPEHSVLIAGLSHWRGDKRNISEERLQARVAEILQVSSIKLYAPPVNEQDPKANRTGINAFMFPTWFLAQVEETWFDSKTQKNYRTRPLLPWGSLVSGKYLNSEKKKVPVVPVRFVQACVKGHLSDIDWYTFVHQDSQKRCRGQLWLDEGGSGNDFAEIYVRCEACKARRPLADATVPNAKVLGPCEGHRPWIGDFAKEPQCINEKKGKPEYNRLLVRSASNAYFSQLLSVISLPDSDTALRDAVSIVYEDFLQYAEDARDVRKERKKQKVFVAIERFSDEEVWQEIQRRQSGQVKEHKSIKQVEIETLLSSPVEVGEDVPESDFYATARDLSNLKPKFTSLIERIVLVHRLREVIAQVGFTRFEAEMPDIDGELDISVRRAALDVEPTWVPAIENRGEGVFIAFRNEAIEEWLQRQAVKKRGRELSRGFDIWCARKGIDQEVDKVKFPGLPYVMLHSLSHLLITAVSLECGYAASSIRERVYAGEAGYGILLYTGSAGSEGTLGGLVEVGKRIEYHLESALEQGKLCSNDPVCAQHKADNEEEERFLHGSACHGCLLIAETSCERRNEFLDRALVVSTVESLGAEFFRS
>NC_019678.1|WP_015118324.1|2752219_2753014_-|hypothetical-protein
MTFLKLSRPNLDKLATALLTRRLSPPFLISSILNYVPVNLSQEIVDELNRLNSQGVDCKHIAYTLRLLAQEKDNSQRIRDRINLVWTGPEITGSRSRDTGVVVRELFSKAKKSVLISSFAIDKGEKAQRLFEVLAQRMEVNPELDVQMFLNIKRPHQSKVAESILLREFADTFRHDIWSGKRLPKLFYDTRSLALDTKQKSCLHAKCIAVDEAQVLVTSANFTQAAHERNIEAGVLLNDTSIAQALRLQFDALVSQKILRPILI
>NC_019678.1|WP_015118323.1|2751107_2751752_+|Uma2-family-endonuclease
MLLSIRRIDVPPGQRVLLRDVTWEEFEAIIEELGEHRAARIAYDRGVLEIMAPLPEHEDDKEIIGDLVKALLEELEIEFRSLGSTTFKNQIMLQGIEPDQCFYIENESKIRGKKRLDLTQDPPPDLALEIDVTSRTHPSIYEALKVPELWRFEKGKLQINLLQNGDYVVSEQSKTFPNFDLAEILPQYLEQSKTAGRNFVIKAFRNWVREQIQN
>NC_019678.1|WP_015118322.1|2750237_2750873_-|hypothetical-protein
MDELIKKIAGLGFPGIILIAVMASTGLTGAAAITAALAFLGGPAGMLGGITVLGLTGLIADALTNVGLEELLTAVYCQRRQSEPQGKLLEEINFLSLFDGDLKERLKATVTDVCGCNTIVAQAITDDTEEVIAILEYVPGMTRAHHRDFKSSNPVMRLRDGSVVKTWKNPFGVDHVFIADRNDNMIYGGFVGWIHSDGLNAAIARIRRNYA
>NC_019678.1|WP_044290869.1|2747487_2749632_-|hypothetical-protein
MNNNTASHHSLHKDVLSTDNYLGEHFRNHSLTGSSQSHPLSFEEDFSSEVTDKVLISQFVDLKSEDLQPEAAFNETPISIEFIDGEIGKRISIPVFNDNLDGNSQVNLSSKNSSKNFTDNTVIGNQNAAVTVAEESPYKNVNSFDTLPASDVNNLEINIQTVGDDTGHLNDISLSQVEGNQYANHNGVASDETFDNQSILQTQSFQDATFNSQDKGEYLDPSVLPVQGTITGGSEEGILLNSEIENNPSIRNVGFREFNNPADAQQTWVIIHGWNDTPDGQFTELAQEIAAANTGDRVLLLDWREAAYNADGINGIDLSALGKGNFRAASWIDPVAEFAVEALNDYYGIDSLGASQSLNLIGHSLGSLVSAEIGRLYRDGLTVENETVVTGNNEGARTITALDPPSARNRDENPLAVDPLEDIYDVDGRIEGIQTPQTFADTSVFSRAYVGEKSIAGNKVLALGADEAFEMTFGTNSELTDFGREHTRVVSAFINTINQQGVLGDLLGLDAYQSLETMSIDDLGELQIIEGSDKGFKGIINVNEDNLVTSLAGILKAGNQDDIVIGSYTNEEMHGTDLLNFGADSPYAGDHNDIFFGESGNDMILGDDNDDILIGGIGTDILNGGAGIDTFIFKPGDGGADKSSTNIIEDFELGIDKIGLTDMSFDQLTFEESSNGTLIMAGSEIIAFLKNTKVQEIQNAEYFINVGENQFAVS
>NC_019678.1|WP_015118320.1|2746500_2747355_-|DUF72-domain-containing-protein
MNFFIGCAVWSYKGWVGEFYPQGTPPKDFLRLYSRRFTTVEGNTTFYALPSQETVKRWAAQTPPEFKFCLKLSRNITHNGSLKPHIKDALKFAEIMRPLDTRLAPIFAQLPPSYAPSSLGDLTAFIEAWQQTQLPLAIEVRHRDWFKQPHADKLTNLLHKFGVGKVILDSRPIYTGENDPQLGSERRKPQLPVLFELTAPFTLIRFISHPNSSINQPFMEEWVTYIKEWLQSDKQIYFFVHCPQEEKSPQTARSFYNLLAQRDIGVSPLPWNQNNHHPKQLSLW
>NC_019678.1|WP_015118319.1|2745678_2746119_-|hypothetical-protein
MNNLLYEESVSYKGYLIIPFVFGKADNYEIYSYKLLSQIGSKSQYHKAENPAKIYGSSIENIINIAKEHIENNSDFVSDGDMFKHRYVFRNNLIIVSQEAGKYYYDHYLPDSLNNIAAPKLFNSEYECWCWVNQGINSLNVGQKVQ
>NC_019678.1|WP_015118329.1|2763649_2766871_-|DNA/RNA-helicase
MLVDAGKIVRVRSRQYLVEDVVTKPSLNEDTLVRLSCLEDDALGEQLEILWEREVDAKVIGKTSWESIVNRGFDNPRLFSAYLHTLRWNCVTSTDPKLFQAPYRAGIEVKAYQLEPLRKALLMPRVGLFIADDVGLGKTIEAGLILREMLMRQKVRRVVISCPPSVVRQWQEEMESRFGLTFVIFDREFVAIRRQERGYGINPWTTHTRFIISHALLRDETYAAPLRDWLGDMSSASMLILDEAHNAAPASGAKYAVDSQLTRTVRDIAPRFEHKLFLSATPHNGHSNSFAALLEILDPQRFCRGVPVRDRKLLDTVMVRRLKQDLREIGEEFPERRVIPIVIDNLEEDAPELKLSRLLQEYRHLREERLRDASKSTQNTAMLVIISLQKRLLSSIEAFARTLKVHRAAIEKQAAKLSTNTVENLPLLLEPPGADDERAELTEEEVQAEEDNQVKVATVAAASCGLSNRELDILEEMTDIANQARYLADARVERLMNWIKENLCPDLGKPNAAWLDKRVIIFTEYTDTKRYLQQKLQEAIAGSEKERERIDVFHGGIGEERREAIKKAFNADPSRHPLRILIATDAAREGVNLQNNCADLYHFDVPWNPSRMEQRNGRIDRKLQRAQVVHCYYFVFAQRTEDKVLKALVRKTATIQKELGSLSPVVQKNLSRLLNGGISHNSASNITNSIEEAELPNLEVINQELEENRLRKEELTKELSRLQKMLKDSRDWLGLSDEHFRNAISASLEILDATPLTPVDSNEACQDSATARWTLPPLDQSTDSTWANTFDTLRPQRQKGQKPWEWRRESPIRPVVFRDPGCLDGDVVHLHLEHRVVQRLLSRFLAQGFLHDELTRACVCLTDDPIPKVIALGRLSIYGQGASRLHDEVIAIAANLSEPAAKKRKKLQPLNEGERDNVLATLEDSLASPRLQKAPETVKTLLKQNATQDIADLIPHLERRAEVLATRAEKKLSERGKKEAVEMKKILEQQQQRINQRKQEIDEEQKQPKQLSLLPTEAEEKRQLEADRRHWEKRLKALAEEINSEPARIEASYQVKAVRVEPVGLVYLWSVSG
>NC_019678.1|WP_015118330.1|2767676_2769575_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGTQVATEVLLSGLEKLEYRGYDSAGIATISEGEVTSVRAKGKLHNLRSKLEQLENPARVGIGHTRWATHGKPEEYNAHPHMDNAMRVAVVMNGIVENYRELREDLKAQGHEFRSDTDTEVIPHLIAQFLKEEVALGETYPDLMFYEAVRKAVNQLTGAFAVAVICADFSDEIILVRQQAPLVIGFGQGEFFCASDTPAIISHTRAVLNLDNGEMARLTPLGVEVYNFAGERLKKQPRLLNMNPVMVEKQGFKHFMLKEIYEQPGVVRACLDAYFSHQDTLDYTNSPVNLGLPEELYTDLEQIQIVACGTSWHAALVGKYLLEQFAGIPTHVHYASEFRYSPTPLTPNTLIIGVTQSGETADTLAALAMEKQRREAKEAKFQPRLLGITNRPESSLGLMVPHIINTLAGIEIGVAATKTFVAQLMAFYALSLDLAYRCKTVSSERIVEMIAGLRMIPQEIEETLQKQEQLTEQLAHEFTETRDFIFLGRGINFPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDEKVPVVAIAMPGGVHEKVISNAQEAKARDSRLIGIAPADDEEVAEVFNDLIPVTTVDELLSPILTVIPLQLLAYHIAARRGLDVDQPRNLAKSVTVE
>NC_019678.1|WP_015118331.1|2769852_2770098_-|photosystem-I-iron-sulfur-center-protein-PsaC
MSHTVKIYDTCIGCTQCVRACPTDVLEMVPWDGCKAQQLAASPRTEDCVGCKRCETACPTDFLSIRVYLGAETTRSMGLAY
>NC_019678.1|WP_015118332.1|2770534_2771326_+|DnaJ-domain-containing-protein
MRELERYYRVLELEPGASLEEVNQAYRDLAFIWHPDRIPQEKHRLQEKARRKLQEINEARDKLRSVKAKYKSKSGSNAPYQPRKTASPSSESRTEWPSSPYPYQPKKTAAPSGSRENSYAPYQQKWTPKSTPTPNKTYQPPQQSDLSGQDFRRANLKGRDLSGRNLSYAKLNGANLSDAFMHKVVLRGADLSDANLFRANLLLADMKEANLQGADLIGADLSGADLRGADLRGARIRSGDRLLVKLIGANLSGAIMPDGSIHQ
>NC_019678.1|WP_015118333.1|2771853_2772339_+|glutathione-peroxidase
MSNAISDVIVKTMDGKDKKLREYLNKVVLIVNVASQCGYTSQYAGLEKLNQNYKEAGLRILAFPCNDFGAQEPGTNDEIIDFCTRNYGTTFELFDKLHAKGEEQHPLYARLTTSVEPKGPIAWNFEKFLVNKQGEVVARFKSSVKPNSPELIAAIERELAQ
>NC_019678.1|WP_015118334.1|2772442_2773267_+|SDR-family-oxidoreductase
MNIAIVGCGYVGYAVAKYWKQNSDLVITATTTTPAKVSALQEVAQKVEVVESSDIKALKSVLKNQDVVLLSVGAKSRDSYEESYLKTAENIVSVLQDNPTVKQLIYTASFSVYGDINAATVDEETPTAPSNANTKILDKAEQILLCASRENLRVCILRLAGIYGEARELVKIFSRAFGETRPGNGETITNWIHLDDIVGAIEFARQQQLDGIYNVVDDARVTSKELIDNLCEKYNKPQVNWDASQTKTRGYNFKVSNQKIKQAGYELIHPQMIF
>NC_019678.1|WP_015118335.1|2773315_2774239_+|alpha/beta-hydrolase
MITQDKTASSSQFYTWNNFRCAYDVQNPTNSTAAGIPLLLIHPIGVGLSRNFWQRFCAEWYKQNNRNLIYNPDLLGCGESDMPHVAYAPIDWAEQLQYFLQTIVKQPVVLVVQGALFPIAIELVKKQPDLIARIILSGPPAWSVITQPAPEWQQKLLWNLLFDSLSGNLFYRYARRKKFLQDFSIKQLFASEADVDDEWLDTLQEGAKNPASRYAVFSFLAGFWRKNYQNAIESIPQPTLAVFGEIASSISKTGKKDTTEKRLADYNLHLPQGSSIKISGRNVLPYESTTEFVEAITPFVNQLTASS
>NC_019678.1|WP_015118336.1|2774352_2775351_+|hypothetical-protein
MWLIKFWTNVLAGCAVIATTLSFAGRQYWVFALMEHLRVQYSLILIIALFVSVLTSKKRIKLWNITCLIALLINLFFILPLFIPPQQNSISLNKSLESNSERILLTHVTLNNKKPDATKAIEYLNKQNTDILFLLEVTPQSLIQLKRGLTNYQLVTAFPKYNSHGIAWFVPKETTKPIKINNFGFIRIPSSNNRPLLKANISFQGREIVLLCFHVISPRNAKTVAYQEIELDALADWSQRLLQTSEQDLIVIGDFNSTPWYGVFRRLLNTSGLINSQRGFGIQTTWHSLLPTVLRIPIDNCLHSKSLTTVRRFIGQDINSDHLPLFIELKLN
>NC_019678.1|WP_015118337.1|2775514_2776531_-|DUF3445-domain-containing-protein
MSSDLLLEVKTVEESKDSAAYFPLQNGRYEIKPGMMPFDTDFGNQSDSKLFQLDSNFESYRQVKLAARKSSLSKHYQTYNYSNSVAKAVAQLIINRLTTEYPQYFNLANHGNQLTLNCQLTKEILYFNQKFQLLKYKSSDKSIFPDYISTLDALAAQIQSDILVISRNQNSDDWMSAIHLCYPNHFSAAEKIGKDFVSVHLPVAGIEKINQRAKAIVNTMIVRKPMMRFAWGLSTDTRLNHHPQPPSGIESKQWYGRNFDISNPRLFLRIERQVMWGLPEYDAAIFTIRTYFRDCREIKKDFVLKNKLISAIESMTPESLIYKDLLESKQDILAWLNQ
>NC_019678.1|WP_015118338.1|2776567_2779159_-|GAF-domain-containing-protein
MTHNFFNTPENNQEFSESESTHILKATVDESGQAFIDEEQPNVDDEWARYFTETVRYIRQSLIKEDILKTATEEVRRVLDCDRVVVYSLNKQSQGLISAESVSPRFTKGLGRIIKDPCFEARYMEKYQDGRVKAIANIYEANLAACYIEQLEKLEVKANLVAPIINEGKLIGLLVAHQCSQPRYWLSHEITWFSQIAMQVGFALDSANILIEVANLKKQADGEAQWTQYFTDTVKLIRQSLNREDILEVATEEVRRILECDRVVIYGLNQDSYGVIIAESVAPRFTKGLGMILQDPCFEEKYFDKYQNGRVRVIPNIYQANLTPCHITQLERLEIKANLVAPIINEGKLLGLLVANQCSQFRDWHSYEVRWFSQIAMQVGFALENANVLAEADSLKDKVDTEAQWTQYFTDTVKLIRQSLNREDILEVATEEVRRILECDRVVIYGLNQDSYGVIIAESVAPRFTKGLGMILQDPCFEEKYFDKYQNGRVRVIPNIYQANLTPCHITQLEKLEIKANLVAPIINEGKLLGLLVANQCSQFRDWHSYEVRWFSQIAMQVGFALENAKLIESNAKANELNKSLFLPQQEDLRKVIIELSQDSKMIFKVFWNKALNISNYVAACGKEIHEILDAAQLIKITGEEVEKQIQRNYDLLESERENIKLTLENIPLLQEAAKDGEMRVKQLDEHCQNLCNYISQLDVRIAKQVSNSENNSEKAQITKEEFSGATAETQPLLTSDIAKINEIVEIIEVRNQEISTWVQSLQNNKQKLDTIVTANIQTSRLISTITKTANSQKEASAQLEKYIESLNQINQQILDKSQFFTNLFAQLTAFAQNSTQKVMFWERLKSFMISFHKLIASVIQKN

Crispr_ID: NC_019678_9

• CRISPR_ID: NC_019678_9
• CRISPR_location: 2770769-2770918
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 2 spacers

Consensus repeat of NC_019678_9

Consensus_repeat	Method
CCTTATCAACCGAGAAAAACTGCT	CRISPRCasFinder

spacers of NC_019678_9

>9.1|2770793|45|NC_019678|CRISPRCasFinder
TCGCCTAGCAGTGAATCTAGGACAGAATGGCCTTCTTCGCCTTAT
>9.2|2770862|33|NC_019678|CRISPRCasFinder
GCTCCTAGTGGTAGTAGAGAGAATTCTTATGCA

CRISPR arrays and Neighbor proteins around NC_019678_9

CRISPR arrays

The CRISPR arrays of NC_019678_9

>merge|NC_019678|9|2770769-2770918|CRISPRCasFinder
CCTTATCAACCGAGAAAAACTGCTTCGCCTAGCAGTGAATCTAGGACAGAATGGCCTTCTTCGCCTTATCCTTATCAACCGAAAAAAACTGCTGCTCCTAGTGGTAGTAGAGAGAATTCTTATGCACCTTATCAACAAAAATGGACTCCT

>NC_019678|9|8|2770769-2770918|CRISPRCasFinder
CCTTATCAACCGAGAAAAACTGCT	TCGCCTAGCAGTGAATCTAGGACAGAATGGCCTTCTTCGCCTTAT
CCTTATCAACCGAAAAAAACTGCT	GCTCCTAGTGGTAGTAGAGAGAATTCTTATGCA
CCTTATCAACAAAAATGGACTCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015118329.1|2763649_2766871_-|DNA/RNA-helicase	unknown	unknown	gnl|CDD|350769
NC_019678.1|WP_015118334.1|2772442_2773267_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187576
NC_019678.1|WP_015118335.1|2773315_2774239_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NC_019678.1|WP_015118324.1|2752219_2753014_-|hypothetical-protein	unknown	unknown	gnl|CDD|197230
NC_019678.1|WP_015118342.1|2782583_2783198_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NC_019678.1|WP_015118333.1|2771853_2772339_+|glutathione-peroxidase	unknown	unknown	gnl|CDD|238207
NC_019678.1|WP_015118337.1|2775514_2776531_-|DUF3445-domain-containing-protein	unknown	unknown	gnl|CDD|378763
NC_019678.1|WP_015118322.1|2750237_2750873_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015118325.1|2753019_2754882_-|DUF1998-domain-containing-protein	unknown	unknown	gnl|CDD|378167
NC_019678.1|WP_015118336.1|2774352_2775351_+|hypothetical-protein	unknown	unknown	gnl|CDD|197318
NC_019678.1|WP_015118339.1|2779760_2780615_-|FkbM-family-methyltransferase	unknown	unknown	gnl|CDD|273628
NC_019678.1|WP_015118330.1|2767676_2769575_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl|CDD|234729
NC_019678.1|WP_015118323.1|2751107_2751752_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NC_019678.1|WP_015118326.1|2755293_2758821_-|helicase-with-metal-binding-cysteine-cluster	unknown	unknown	gnl|CDD|197757
NC_019678.1|WP_015118331.1|2769852_2770098_-|photosystem-I-iron-sulfur-center-protein-PsaC	unknown	unknown	gnl|CDD|177005
NC_019678.1|WP_015118338.1|2776567_2779159_-|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|376570
NC_019678.1|WP_015118340.1|2780722_2781640_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176114
NC_019678.1|WP_015118327.1|2759072_2759333_+|HigA-family-addiction-module-antidote-protein	unknown	unknown	gnl|CDD|225635
NC_019678.1|WP_015118341.1|2781862_2782525_+|AhpC/TSA-family-protein	unknown	unknown	gnl|CDD|239268
NC_019678.1|WP_015118328.1|2759587_2759992_-|IS200/IS605-family-transposase	unknown	unknown	gnl|CDD|376616

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015118329.1|2763649_2766871_-|DNA/RNA-helicase	gnl|CDD|350769	cd18011, DEXDc_RapA, DEXH-box helicase domain of RapA. In bacteria, RapA is an RNA polymerase (RNAP)-associated SWI2/SNF2 (switch/sucrose non-fermentable) protein that mediates RNAP recycling during transcription. The ATPase activity of RapA is stimulated by its interaction with RNAP and inhibited by its N-terminal domain. The conformational changes of RapA and its interaction with RNAP are essential for RNAP recycling. RapA is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	2.28469e-57
NC_019678.1|WP_015118334.1|2772442_2773267_+|SDR-family-oxidoreductase	gnl|CDD|187576	cd05266, SDR_a4, atypical (a) SDRs, subgroup 4. Atypical SDRs in this subgroup are poorly defined, one member is identified as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is related to, but is different from, the archetypical SDRs, GXGXXG. This subgroup also lacks most of the characteristic active site residues of the SDRs; however, the upstream Ser is present at the usual place, and some potential catalytic residues are present in place of the usual YXXXK active site motif. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.23372e-62
NC_019678.1|WP_015118335.1|2773315_2774239_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.89063e-12
NC_019678.1|WP_015118324.1|2752219_2753014_-|hypothetical-protein	gnl|CDD|197230	cd09132, PLDc_unchar4, Putative catalytic domain of uncharacterized phospholipase D-like proteins. Putative catalytic domain of uncharacterized phospholipase D (PLD, EC 3.1.4.4)-like proteins. Members of this subfamily contain one copy of HKD motif (H-x-K-x(4)-D, where x represents any amino acid residue) that characterizes the PLD superfamily.	4.75344e-27
NC_019678.1|WP_015118342.1|2782583_2783198_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	5.8376e-25
NC_019678.1|WP_015118333.1|2771853_2772339_+|glutathione-peroxidase	gnl|CDD|238207	cd00340, GSH_Peroxidase, Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per subunit, which is involved in catalysis. Different isoenzymes are known in mammals,which are involved in protection against reactive oxygen species, redox regulation of many metabolic processes, peroxinitrite scavenging, and modulation of inflammatory processes.	2.86733e-75
NC_019678.1|WP_015118337.1|2775514_2776531_-|DUF3445-domain-containing-protein	gnl|CDD|378763	pfam11927, DUF3445, Protein of unknown function (DUF3445). This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 264 to 418 amino acids in length. This protein has a conserved RLP sequence motif. This protein has two completely conserved R residues that may be functionally important.	6.03416e-49
NC_019678.1|WP_015118325.1|2753019_2754882_-|DUF1998-domain-containing-protein	gnl|CDD|378167	pfam09369, DUF1998, Domain of unknown function (DUF1998). This family of proteins are functionally uncharacterized. They are mainly found in helicase proteins so could be RNA binding. This family includes a probable zinc binding motif at its C-terminus.	1.18181e-12
NC_019678.1|WP_015118336.1|2774352_2775351_+|hypothetical-protein	gnl|CDD|197318	cd09084, EEP-2, Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; uncharacterized family 2. This family of uncharacterized proteins belongs to a superfamily that includes the catalytic domain (exonuclease/endonuclease/phosphatase, EEP, domain) of a diverse set of proteins including the ExoIII family of apurinic/apyrimidinic (AP) endonucleases, inositol polyphosphate 5-phosphatases (INPP5), neutral sphingomyelinases (nSMases), deadenylases (such as the vertebrate circadian-clock regulated nocturnin), bacterial cytolethal distending toxin B (CdtB), deoxyribonuclease 1 (DNase1), the endonuclease domain of the non-LTR retrotransposon LINE-1, and related domains. These diverse enzymes share a common catalytic mechanism of cleaving phosphodiester bonds; their substrates range from nucleic acids to phospholipids and perhaps, proteins.	2.68698e-14
NC_019678.1|WP_015118339.1|2779760_2780615_-|FkbM-family-methyltransferase	gnl|CDD|273628	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family. Members of this family are characterized by two well-conserved short regions separated by a variable in both sequence and length. The first of the two regions is found in a large number of proteins outside this subfamily, a number of which have been characterized as methyltransferases. One member of the present family, FkbM, was shown to be required for a specific methylation in the biosynthesis of the immunosuppressant FK506 in Streptomyces strain MA6548.	7.2299e-27
NC_019678.1|WP_015118330.1|2767676_2769575_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl|CDD|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NC_019678.1|WP_015118323.1|2751107_2751752_+|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	4.98043e-14
NC_019678.1|WP_015118326.1|2755293_2758821_-|helicase-with-metal-binding-cysteine-cluster	gnl|CDD|197757	smart00490, HELICc, helicase superfamily c-terminal domain.	6.86208e-09
NC_019678.1|WP_015118331.1|2769852_2770098_-|photosystem-I-iron-sulfur-center-protein-PsaC	gnl|CDD|177005	CHL00065, psaC, photosystem I subunit VII.	9.42204e-53
NC_019678.1|WP_015118338.1|2776567_2779159_-|GAF-domain-containing-protein	gnl|CDD|376570	pfam01590, GAF, GAF domain. This domain is present in cGMP-specific phosphodiesterases, adenylyl and guanylyl cyclases, phytochromes, FhlA and NifA. Adenylyl and guanylyl cyclases catalyze ATP and GTP to the second messengers cAMP and cGMP, respectively, these products up-regulating catalytic activity by binding to the regulatory GAF domain(s). The opposite hydrolysis reaction is catalyzed by phosphodiesterase. cGMP-dependent 3',5'-cyclic phosphodiesterase catalyzes the conversion of guanosine 3',5'-cyclic phosphate to guanosine 5'-phosphate. Here too, cGMP regulates catalytic activity by GAF-domain binding. Phytochromes are regulatory photoreceptors in plants and bacteria which exist in two thermally-stable states that are reversibly inter-convertible by light: the Pr state absorbs maximally in the red region of the spectrum, while the Pfr state absorbs maximally in the far-red region. This domain is also found in FhlA (formate hydrogen lyase transcriptional activator) and NifA, a transcriptional activator which is required for activation of most Nif operons which are directly involved in nitrogen fixation. NifA interacts with sigma-54.	3.76567e-21
NC_019678.1|WP_015118340.1|2780722_2781640_-|LysR-family-transcriptional-regulator	gnl|CDD|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.15133e-92
NC_019678.1|WP_015118327.1|2759072_2759333_+|HigA-family-addiction-module-antidote-protein	gnl|CDD|225635	COG3093, VapI, Plasmid maintenance system antidote protein [General function prediction only].	2.03644e-19
NC_019678.1|WP_015118341.1|2781862_2782525_+|AhpC/TSA-family-protein	gnl|CDD|239268	cd02970, PRX_like2, Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these proteins do not contain the other two residues of the catalytic triad of PRX. PRXs confer a protective antioxidant role in cells through their peroxidase activity in which hydrogen peroxide, peroxynitrate, and organic hydroperoxides are reduced and detoxified using reducing equivalents derived from either thioredoxin, glutathione, trypanothione and AhpF. TRXs alter the redox state of target proteins by catalyzing the reduction of their disulfide bonds via the CXXC motif using reducing equivalents derived from either NADPH or ferredoxins.	2.21434e-46
NC_019678.1|WP_015118328.1|2759587_2759992_-|IS200/IS605-family-transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	4.24635e-32

Protein sequences

>NC_019678.1|WP_015118331.1|2769852_2770098_-|photosystem-I-iron-sulfur-center-protein-PsaC
MSHTVKIYDTCIGCTQCVRACPTDVLEMVPWDGCKAQQLAASPRTEDCVGCKRCETACPTDFLSIRVYLGAETTRSMGLAY
>NC_019678.1|WP_015118330.1|2767676_2769575_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGTQVATEVLLSGLEKLEYRGYDSAGIATISEGEVTSVRAKGKLHNLRSKLEQLENPARVGIGHTRWATHGKPEEYNAHPHMDNAMRVAVVMNGIVENYRELREDLKAQGHEFRSDTDTEVIPHLIAQFLKEEVALGETYPDLMFYEAVRKAVNQLTGAFAVAVICADFSDEIILVRQQAPLVIGFGQGEFFCASDTPAIISHTRAVLNLDNGEMARLTPLGVEVYNFAGERLKKQPRLLNMNPVMVEKQGFKHFMLKEIYEQPGVVRACLDAYFSHQDTLDYTNSPVNLGLPEELYTDLEQIQIVACGTSWHAALVGKYLLEQFAGIPTHVHYASEFRYSPTPLTPNTLIIGVTQSGETADTLAALAMEKQRREAKEAKFQPRLLGITNRPESSLGLMVPHIINTLAGIEIGVAATKTFVAQLMAFYALSLDLAYRCKTVSSERIVEMIAGLRMIPQEIEETLQKQEQLTEQLAHEFTETRDFIFLGRGINFPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDEKVPVVAIAMPGGVHEKVISNAQEAKARDSRLIGIAPADDEEVAEVFNDLIPVTTVDELLSPILTVIPLQLLAYHIAARRGLDVDQPRNLAKSVTVE
>NC_019678.1|WP_015118329.1|2763649_2766871_-|DNA/RNA-helicase
MLVDAGKIVRVRSRQYLVEDVVTKPSLNEDTLVRLSCLEDDALGEQLEILWEREVDAKVIGKTSWESIVNRGFDNPRLFSAYLHTLRWNCVTSTDPKLFQAPYRAGIEVKAYQLEPLRKALLMPRVGLFIADDVGLGKTIEAGLILREMLMRQKVRRVVISCPPSVVRQWQEEMESRFGLTFVIFDREFVAIRRQERGYGINPWTTHTRFIISHALLRDETYAAPLRDWLGDMSSASMLILDEAHNAAPASGAKYAVDSQLTRTVRDIAPRFEHKLFLSATPHNGHSNSFAALLEILDPQRFCRGVPVRDRKLLDTVMVRRLKQDLREIGEEFPERRVIPIVIDNLEEDAPELKLSRLLQEYRHLREERLRDASKSTQNTAMLVIISLQKRLLSSIEAFARTLKVHRAAIEKQAAKLSTNTVENLPLLLEPPGADDERAELTEEEVQAEEDNQVKVATVAAASCGLSNRELDILEEMTDIANQARYLADARVERLMNWIKENLCPDLGKPNAAWLDKRVIIFTEYTDTKRYLQQKLQEAIAGSEKERERIDVFHGGIGEERREAIKKAFNADPSRHPLRILIATDAAREGVNLQNNCADLYHFDVPWNPSRMEQRNGRIDRKLQRAQVVHCYYFVFAQRTEDKVLKALVRKTATIQKELGSLSPVVQKNLSRLLNGGISHNSASNITNSIEEAELPNLEVINQELEENRLRKEELTKELSRLQKMLKDSRDWLGLSDEHFRNAISASLEILDATPLTPVDSNEACQDSATARWTLPPLDQSTDSTWANTFDTLRPQRQKGQKPWEWRRESPIRPVVFRDPGCLDGDVVHLHLEHRVVQRLLSRFLAQGFLHDELTRACVCLTDDPIPKVIALGRLSIYGQGASRLHDEVIAIAANLSEPAAKKRKKLQPLNEGERDNVLATLEDSLASPRLQKAPETVKTLLKQNATQDIADLIPHLERRAEVLATRAEKKLSERGKKEAVEMKKILEQQQQRINQRKQEIDEEQKQPKQLSLLPTEAEEKRQLEADRRHWEKRLKALAEEINSEPARIEASYQVKAVRVEPVGLVYLWSVSG
>NC_019678.1|WP_015118328.1|2759587_2759992_-|IS200/IS605-family-transposase
MSLWRIYYHIIWTTKQRQPLISADKEPELYNYIIGKSDFLNCIIHAIGGMEDHIHVIVSIPPTIAISEYVKKVKGSSSYHINHNTPTTSDKFSWQEGYGVFSLGSKQLEKAVIYVKNQKIHHSQGTTNSYLENV
>NC_019678.1|WP_015118327.1|2759072_2759333_+|HigA-family-addiction-module-antidote-protein
MTQNLTSARAISPGKVLHRELQARGWTQKYLAEIMGCGVKNINEIIQEAKEVTPEIAIELSQVLGTSAEFWTNLETKYQLHLSGKE
>NC_019678.1|WP_015118326.1|2755293_2758821_-|helicase-with-metal-binding-cysteine-cluster
MTAAIPNQVQSNQSSTVRAHLIEALQLDLIGPTPDDINYAEEILDQAPSKGYLTGFLVPYGASIEQRTDDNGDDELDQVSGGAAGEDENVPEKTFAKKAFFPSSIGLSLLVNQNTSHLNVTVAWGDYYPYKENIDTDTENKTIPQEEQLEATDEKQTQTIPGCWKRIPRQQEITIPIGEHNPKQLELPLNKGGVSPNLNIPIPDSNGLELVVSVRPVASKELVPAGSLSVSVFLVNKRVPTNDKERDTTYTFQTSLAIRTIEPFVPRPNLRGRDNDDWDESVADLQYRDNYEYAVGHNVSAVAVTNVDGNCNYVRTAWIPTADVEKVIATEDEFKDVELGMEELAKAQTPEALQNMLSPMVNAYGDWIEQQRLTSPQEPKRFNIASDLLNRAEIAKNRINAGIQALTDPDIFTAFQIGNRAIATYIRQRKTHGQNITPESIAPPKWRPFQLAFILMNLLGVANPEHNERELVDLLFFPTGGGKTEAYLGLAAFTLVLRRLHNPDPKTKIKSAGLSVLMRYTLRLLTLDQLGRAAAMICALELEREKNPELLGTWSFEIGLWVGQAATPNRMGKKGDNDDYSARKRTLDFQKNNRNPSPIPLENCPWCGTKFDRNSFQLHPNPDQPSNLHVYCSNRRCDFSGRKGKNLPIVTVDEPIYRRLPCFIIATVDKFASLPWVGETGALFGKVDRYDQNGFYGPTQPGRGKALGSHLPPPDLIIQDELHLISGPLGTMVGLYETAIDALCSREINGKPTRPKIVASTATVRRASKQIQALFGRSEVDIFPPPGPDRRDSFFAKTVPASEKNARTYVGIAAQGRSAKVVLLRTYLALLGAAQKHWLAAGGKKNPDNPADPYMTLLGYFNSLRELGGSRRIVEDEVKTRLNRYSQRKRIGEASGLFADRKIDDEPEELTSRVSTSEVANTKQRLESTFDKNDKVDVVLATNMISVGLDITRLGLMVVLGQPKTAAEYIQATSRVGRDEKRPGLVVTLLNIHRPRDRSHYERFCAWHSSFYRAVEATSVTPFSPRAIDRGIAAITVALARLGHTKMTAPTNAIEILQNRQELEFVVDKIAQRAEMHDKELSASDSEALRQKVRNTVKDLLDLWERIANDKINLQYQREVGEAPPLIFEPLDPELLNQPLEARKFKAQRSLRDVEPTVNLWVINPNGDEVEEVKK
>NC_019678.1|WP_015118325.1|2753019_2754882_-|DUF1998-domain-containing-protein
MSKSNKKIPPAGQIRQSQILSTFGSGSMVDLPEHSVLIAGLSHWRGDKRNISEERLQARVAEILQVSSIKLYAPPVNEQDPKANRTGINAFMFPTWFLAQVEETWFDSKTQKNYRTRPLLPWGSLVSGKYLNSEKKKVPVVPVRFVQACVKGHLSDIDWYTFVHQDSQKRCRGQLWLDEGGSGNDFAEIYVRCEACKARRPLADATVPNAKVLGPCEGHRPWIGDFAKEPQCINEKKGKPEYNRLLVRSASNAYFSQLLSVISLPDSDTALRDAVSIVYEDFLQYAEDARDVRKERKKQKVFVAIERFSDEEVWQEIQRRQSGQVKEHKSIKQVEIETLLSSPVEVGEDVPESDFYATARDLSNLKPKFTSLIERIVLVHRLREVIAQVGFTRFEAEMPDIDGELDISVRRAALDVEPTWVPAIENRGEGVFIAFRNEAIEEWLQRQAVKKRGRELSRGFDIWCARKGIDQEVDKVKFPGLPYVMLHSLSHLLITAVSLECGYAASSIRERVYAGEAGYGILLYTGSAGSEGTLGGLVEVGKRIEYHLESALEQGKLCSNDPVCAQHKADNEEEERFLHGSACHGCLLIAETSCERRNEFLDRALVVSTVESLGAEFFRS
>NC_019678.1|WP_015118324.1|2752219_2753014_-|hypothetical-protein
MTFLKLSRPNLDKLATALLTRRLSPPFLISSILNYVPVNLSQEIVDELNRLNSQGVDCKHIAYTLRLLAQEKDNSQRIRDRINLVWTGPEITGSRSRDTGVVVRELFSKAKKSVLISSFAIDKGEKAQRLFEVLAQRMEVNPELDVQMFLNIKRPHQSKVAESILLREFADTFRHDIWSGKRLPKLFYDTRSLALDTKQKSCLHAKCIAVDEAQVLVTSANFTQAAHERNIEAGVLLNDTSIAQALRLQFDALVSQKILRPILI
>NC_019678.1|WP_015118323.1|2751107_2751752_+|Uma2-family-endonuclease
MLLSIRRIDVPPGQRVLLRDVTWEEFEAIIEELGEHRAARIAYDRGVLEIMAPLPEHEDDKEIIGDLVKALLEELEIEFRSLGSTTFKNQIMLQGIEPDQCFYIENESKIRGKKRLDLTQDPPPDLALEIDVTSRTHPSIYEALKVPELWRFEKGKLQINLLQNGDYVVSEQSKTFPNFDLAEILPQYLEQSKTAGRNFVIKAFRNWVREQIQN
>NC_019678.1|WP_015118322.1|2750237_2750873_-|hypothetical-protein
MDELIKKIAGLGFPGIILIAVMASTGLTGAAAITAALAFLGGPAGMLGGITVLGLTGLIADALTNVGLEELLTAVYCQRRQSEPQGKLLEEINFLSLFDGDLKERLKATVTDVCGCNTIVAQAITDDTEEVIAILEYVPGMTRAHHRDFKSSNPVMRLRDGSVVKTWKNPFGVDHVFIADRNDNMIYGGFVGWIHSDGLNAAIARIRRNYA
>NC_019678.1|WP_015118333.1|2771853_2772339_+|glutathione-peroxidase
MSNAISDVIVKTMDGKDKKLREYLNKVVLIVNVASQCGYTSQYAGLEKLNQNYKEAGLRILAFPCNDFGAQEPGTNDEIIDFCTRNYGTTFELFDKLHAKGEEQHPLYARLTTSVEPKGPIAWNFEKFLVNKQGEVVARFKSSVKPNSPELIAAIERELAQ
>NC_019678.1|WP_015118334.1|2772442_2773267_+|SDR-family-oxidoreductase
MNIAIVGCGYVGYAVAKYWKQNSDLVITATTTTPAKVSALQEVAQKVEVVESSDIKALKSVLKNQDVVLLSVGAKSRDSYEESYLKTAENIVSVLQDNPTVKQLIYTASFSVYGDINAATVDEETPTAPSNANTKILDKAEQILLCASRENLRVCILRLAGIYGEARELVKIFSRAFGETRPGNGETITNWIHLDDIVGAIEFARQQQLDGIYNVVDDARVTSKELIDNLCEKYNKPQVNWDASQTKTRGYNFKVSNQKIKQAGYELIHPQMIF
>NC_019678.1|WP_015118335.1|2773315_2774239_+|alpha/beta-hydrolase
MITQDKTASSSQFYTWNNFRCAYDVQNPTNSTAAGIPLLLIHPIGVGLSRNFWQRFCAEWYKQNNRNLIYNPDLLGCGESDMPHVAYAPIDWAEQLQYFLQTIVKQPVVLVVQGALFPIAIELVKKQPDLIARIILSGPPAWSVITQPAPEWQQKLLWNLLFDSLSGNLFYRYARRKKFLQDFSIKQLFASEADVDDEWLDTLQEGAKNPASRYAVFSFLAGFWRKNYQNAIESIPQPTLAVFGEIASSISKTGKKDTTEKRLADYNLHLPQGSSIKISGRNVLPYESTTEFVEAITPFVNQLTASS
>NC_019678.1|WP_015118336.1|2774352_2775351_+|hypothetical-protein
MWLIKFWTNVLAGCAVIATTLSFAGRQYWVFALMEHLRVQYSLILIIALFVSVLTSKKRIKLWNITCLIALLINLFFILPLFIPPQQNSISLNKSLESNSERILLTHVTLNNKKPDATKAIEYLNKQNTDILFLLEVTPQSLIQLKRGLTNYQLVTAFPKYNSHGIAWFVPKETTKPIKINNFGFIRIPSSNNRPLLKANISFQGREIVLLCFHVISPRNAKTVAYQEIELDALADWSQRLLQTSEQDLIVIGDFNSTPWYGVFRRLLNTSGLINSQRGFGIQTTWHSLLPTVLRIPIDNCLHSKSLTTVRRFIGQDINSDHLPLFIELKLN
>NC_019678.1|WP_015118337.1|2775514_2776531_-|DUF3445-domain-containing-protein
MSSDLLLEVKTVEESKDSAAYFPLQNGRYEIKPGMMPFDTDFGNQSDSKLFQLDSNFESYRQVKLAARKSSLSKHYQTYNYSNSVAKAVAQLIINRLTTEYPQYFNLANHGNQLTLNCQLTKEILYFNQKFQLLKYKSSDKSIFPDYISTLDALAAQIQSDILVISRNQNSDDWMSAIHLCYPNHFSAAEKIGKDFVSVHLPVAGIEKINQRAKAIVNTMIVRKPMMRFAWGLSTDTRLNHHPQPPSGIESKQWYGRNFDISNPRLFLRIERQVMWGLPEYDAAIFTIRTYFRDCREIKKDFVLKNKLISAIESMTPESLIYKDLLESKQDILAWLNQ
>NC_019678.1|WP_015118338.1|2776567_2779159_-|GAF-domain-containing-protein
MTHNFFNTPENNQEFSESESTHILKATVDESGQAFIDEEQPNVDDEWARYFTETVRYIRQSLIKEDILKTATEEVRRVLDCDRVVVYSLNKQSQGLISAESVSPRFTKGLGRIIKDPCFEARYMEKYQDGRVKAIANIYEANLAACYIEQLEKLEVKANLVAPIINEGKLIGLLVAHQCSQPRYWLSHEITWFSQIAMQVGFALDSANILIEVANLKKQADGEAQWTQYFTDTVKLIRQSLNREDILEVATEEVRRILECDRVVIYGLNQDSYGVIIAESVAPRFTKGLGMILQDPCFEEKYFDKYQNGRVRVIPNIYQANLTPCHITQLERLEIKANLVAPIINEGKLLGLLVANQCSQFRDWHSYEVRWFSQIAMQVGFALENANVLAEADSLKDKVDTEAQWTQYFTDTVKLIRQSLNREDILEVATEEVRRILECDRVVIYGLNQDSYGVIIAESVAPRFTKGLGMILQDPCFEEKYFDKYQNGRVRVIPNIYQANLTPCHITQLEKLEIKANLVAPIINEGKLLGLLVANQCSQFRDWHSYEVRWFSQIAMQVGFALENAKLIESNAKANELNKSLFLPQQEDLRKVIIELSQDSKMIFKVFWNKALNISNYVAACGKEIHEILDAAQLIKITGEEVEKQIQRNYDLLESERENIKLTLENIPLLQEAAKDGEMRVKQLDEHCQNLCNYISQLDVRIAKQVSNSENNSEKAQITKEEFSGATAETQPLLTSDIAKINEIVEIIEVRNQEISTWVQSLQNNKQKLDTIVTANIQTSRLISTITKTANSQKEASAQLEKYIESLNQINQQILDKSQFFTNLFAQLTAFAQNSTQKVMFWERLKSFMISFHKLIASVIQKN
>NC_019678.1|WP_015118339.1|2779760_2780615_-|FkbM-family-methyltransferase
MLNWNLVREVGYPKFFYRYFIRQFYKRVLQQDNILKLNQGVSINLPRNSKFGTELFLKNGFVDWGSEEYLIKYLDKSKSFLDIGANIGYYSLLVSPYCHSVYAFEPDLRSIAALKQNAQKVDNIQVIQEAVYSKVGEMQFDISKLPELSSLNTKSKNYNNCINVKVDTLDNFASKHPDLKVTAIKTDVEGADTEVLLGGKNLIKKEQPLILSEAFPDSRVLKFAKELDYLIFAFIKFKDKSKMHLKPKFIQITKYPQGFRPKMIFLVPTRLHNQFLQLVQPHEL
>NC_019678.1|WP_015118340.1|2780722_2781640_-|LysR-family-transcriptional-regulator
MDRIAWMQSFVRTVETGSFSAVARELETTQPTISKQIAALEEYLDVQLLVRSTRTLNLTEAGEQFYQQCLRVLETLAEAEASVGERKKPSGTLRVNCGVSFGQLQIVPRIKAFLQRYPDIKLDLMMNDGFIDLVEEGVDLAIRIGNHQDTSLISQRIGTTRRVTAASHEYFEENGEPRKPQELIHHNCIVYTRLSTGNEWYFQSQDKTIKVKVTGNFQTNNSTAIREAVLSGIGISVLPIWLFGDCINNGKLKVILKEYQPTPLPINAVYRRGRFIPAKVRCFINFLAQEFEIDPWVSGFGQVKG
>NC_019678.1|WP_015118341.1|2781862_2782525_+|AhpC/TSA-family-protein
MNLQTALNNFQAEFKEKVPAEAAATMERAANELLQEFEARNLIKIGDIAPDFTLADAVGNKISLKERLTKGAVILTFYRGGWCPYCNLELRAYQQLLPEIERLGASLIAVSPQTPDASLSTAEKNDLEFDVLSDVDLTAARTYGLVFELSQELKALYQQWGIDLPKNNGNNEWKLPVPGTFVIDQNGRIAASYINTDYTKRLEPKEAIAALQKLSHAAAV
>NC_019678.1|WP_015118342.1|2782583_2783198_-|class-I-SAM-dependent-methyltransferase
MGFYSQKIFPYLLDWSLSDSTFNQYRQEVLAEVEGEVLEIGFGTGLNLSFYPDEIHKIITVDNNPGVNKLAQKRIEKSSITVDHRILSGENLPMADNTFDSVVSTWTLCSIEKVEQAVKEIHRVLKPGGKFFFIEHGLSNEPSIQTWQNRLNPIQNVIADGCNLNRNIRSIVQQQFIRVNVEEFYADKTPKFLGYMYQGVAVKG

Crispr_ID: NC_019678_10

• CRISPR_ID: NC_019678_10
• CRISPR_location: 2950539-2950645
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 1 spacers

Consensus repeat of NC_019678_10

Consensus_repeat	Method
ATTTGGTTGTAGTTGATAAATTACCGTAACCGTCACAGC	CRISPRCasFinder

spacers of NC_019678_10

>10.1|2950578|29|NC_019678|CRISPRCasFinder
TGTTTGGTGCGTGACGGTAAATTCAAATG

CRISPR arrays and Neighbor proteins around NC_019678_10

CRISPR arrays

The CRISPR arrays of NC_019678_10

>merge|NC_019678|10|2950539-2950645|CRISPRCasFinder
ATTTGGTTGTAGTTGATAAATTACCGTAACCGTCACAGCTGTTTGGTGCGTGACGGTAAATTCAAATGATTTGGTTGTAGTTGATAAATTACCGTAACCGTCACAGC

>NC_019678|10|9|2950539-2950645|CRISPRCasFinder
ATTTGGTTGTAGTTGATAAATTACCGTAACCGTCACAGC	TGTTTGGTGCGTGACGGTAAATTCAAATG
ATTTGGTTGTAGTTGATAAATTACCGTAACCGTCACAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015118477.1|2959513_2960272_-|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|224331
NC_019678.1|WP_015118465.1|2942027_2943353_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226359
NC_019678.1|WP_015118474.1|2954114_2954636_+|DUF456-family-protein	unknown	unknown	gnl|CDD|225395
NC_019678.1|WP_015118470.1|2950092_2950389_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_019678.1|WP_015118475.1|2954884_2955640_-|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	gnl|CDD|131644
NC_019678.1|WP_015118464.1|2941411_2941627_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015118473.1|2953342_2953978_+|cofactor-assembly-of-complex-C-subunit-B	unknown	unknown	gnl|CDD|371397
NC_019678.1|WP_015118466.1|2943472_2946001_-|NTP-transferase-domain-containing-protein	unknown	unknown	gnl|CDD|100097
NC_019678.1|WP_015118461.1|2936494_2937184_-|hypothetical-protein	unknown	unknown	gnl|CDD|182035
NC_019678.1|WP_015118476.1|2956183_2956993_-|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	unknown
NC_019678.1|WP_015118462.1|2937831_2939700_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224048
NC_019678.1|WP_015118471.1|2950688_2952245_-|DNA-repair-protein-RadA	unknown	unknown	gnl|CDD|236994
NC_019678.1|WP_015118479.1|2960914_2961136_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015118468.1|2947646_2948177_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015118467.1|2946416_2947529_-|amidoligase	unknown	unknown	gnl|CDD|378827
NC_019678.1|WP_015118476.1|2957883_2958693_-|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	unknown
NC_019678.1|WP_083894125.1|2960403_2960820_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_019678.1|WP_015118463.1|2940100_2940649_-|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|223702
NC_019678.1|WP_015118469.1|2948486_2949701_-|glycosyltransferase	unknown	unknown	gnl|CDD|340845
NC_019678.1|WP_015118472.1|2952425_2953154_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|214376

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015118477.1|2959513_2960272_-|HEAT-repeat-domain-containing-protein	gnl|CDD|224331	COG1413, COG1413, FOG: HEAT repeat [Energy production and conversion].	2.42256e-25
NC_019678.1|WP_015118465.1|2942027_2943353_+|ABC-transporter-ATP-binding-protein	gnl|CDD|226359	COG3839, MalK, ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism].	4.92037e-158
NC_019678.1|WP_015118474.1|2954114_2954636_+|DUF456-family-protein	gnl|CDD|225395	COG2839, COG2839, Uncharacterized protein conserved in bacteria [Function unknown].	1.24788e-24
NC_019678.1|WP_015118470.1|2950092_2950389_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.09897e-18
NC_019678.1|WP_015118475.1|2954884_2955640_-|PEP-CTERM-sorting-domain-containing-protein	gnl|CDD|131644	TIGR02595, conserved_hypothetical_protein, PEP-CTERM protein-sorting domain. This model describes a 25-residue domain that includes a near-invariant Pro-Glu-Pro (PEP) motif, a thirteen residue strongly hydrophobic sequence likely to span the membrane, and a five-residue strongly basic motif that often contains four Arg residues. In nearly every case, this motif is found within nine residues, and usually within five residues, of the extreme C-terminus of the protein. Proteins with this motif typically have signal sequences at the N-terminus. This region appears many times per genome or not at all, and co-occurs in genomes with a proposed protein-sorting integral membrane protein we designate exosortase (see TIGR02602). PEP-CTERM proteins frequently are poorly conserved, Ser/Thr-rich proteins and may become extensively modified proteinaceous constituents of extracellular material in bacterial biofilms. [Cell envelope, Surface structures].	0.00876323
NC_019678.1|WP_015118473.1|2953342_2953978_+|cofactor-assembly-of-complex-C-subunit-B	gnl|CDD|371397	pfam11152, CCB2_CCB4, Cofactor assembly of complex C subunit B, CCB2/CCB4. Cofactor maturation pathways such as the CCB system (system IV) for cytochrome c-heme attachment are conserved in all organisms performing oxygenic photosynthesis. The CCB system consists of four proteins: CCB1-4. CCB2 and CCB4 are paralogues derived from a unique cyanobacterial ancestor. Orthologues are conserved in higher plants.	4.75743e-113
NC_019678.1|WP_015118466.1|2943472_2946001_-|NTP-transferase-domain-containing-protein	gnl|CDD|100097	cd05805, MPG1_transferase, GTP-mannose-1-phosphate guanyltransferase (MPG1 transferase), also known as GDP-mannose pyrophosphorylase, is a bifunctional enzyme with both phosphomannose isomerase (PMI) activity and GDP-mannose phosphorylase (GMP) activity. The protein contains an N-terminal NTP transferase domain, an L-beta-H domain, and a C-terminal PGM-like domain that belongs to the alpha-D-phosphohexomutase superfamily. This subfamily is limited to bacteria and archaea. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this group appear to lack conserved residues necessary for metal binding and catalytic activity. Other members of this superfamily include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
NC_019678.1|WP_015118461.1|2936494_2937184_-|hypothetical-protein	gnl|CDD|182035	PRK09699, PRK09699, D-allose ABC transporter permease.	0.00997947
NC_019678.1|WP_015118462.1|2937831_2939700_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0
NC_019678.1|WP_015118471.1|2950688_2952245_-|DNA-repair-protein-RadA	gnl|CDD|236994	PRK11823, PRK11823, DNA repair protein RadA; Provisional.	0
NC_019678.1|WP_015118472.1|2952425_2953154_+|response-regulator-transcription-factor	gnl|CDD|214376	CHL00148, orf27, Ycf27; Reviewed.	1.74304e-156
NC_019678.1|WP_015118467.1|2946416_2947529_-|amidoligase	gnl|CDD|378827	pfam12224, Amidoligase_2, Putative amidoligase enzyme. This family of proteins are likely to act as amidoligase enzymes Protein in this family are found in conserved gene neighborhoods encoding a glutamine amidotransferase-like thiol peptidase (in proteobacteria) or an Aig2 family cyclotransferase protein (in firmicutes).	3.84264e-10
NC_019678.1|WP_083894125.1|2960403_2960820_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.96661e-18
NC_019678.1|WP_015118463.1|2940100_2940649_-|single-stranded-DNA-binding-protein	gnl|CDD|223702	COG0629, Ssb, Single-stranded DNA-binding protein [DNA replication, recombination, and repair].	2.55653e-20
NC_019678.1|WP_015118469.1|2948486_2949701_-|glycosyltransferase	gnl|CDD|340845	cd03818, GT4_ExpC-like, Rhizobium meliloti ExpC and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).	1.42717e-169

Protein sequences

>NC_019678.1|WP_015118470.1|2950092_2950389_-|protein-kinase
MQLWQPNQQLQNGKFTIQKVLGAGGYGVTYSAIEASTNNVVAIKTLNPIHHSQGDFEQQQDNFVKEAFRLAKCSHPHIVKVHDVITAIRLFIVLILNS
>NC_019678.1|WP_015118469.1|2948486_2949701_-|glycosyltransferase
MRILFLHPNFPAQFRHLAVALAKNSNNQVVFGTNRREGSLPGVIKAMYGSSREVRPETHHYVRPLEKAVLQGQGVYRLAEELKQKGFIPDIVYGHSGWGPTLFIKDAFPESTLLCYFEWFYQAHGSDADFDPIDPLSHDDEARIRIKNAPILIDLYSCDRGLSPTNWQRQQFPTEYHSKITVNHDGIDTKYFKPQPEAKLVLPRINLDLSSVEEIITYVARGMEPYRGFPQFIETVALIQQKRPNCHVVIVGEDRVAYGKQLPDNKTYKQLMLEKVPLDMTRVHFTGLLPYGEYLQVLQASSVHIYLTRPFVLSWSMLEALSTGCLIVASNTAPVTEVIEDGVNGLLVDFFSPEQICSRVEEVLNHPDKMSSIRERARETILQKYDLAQLLPKHLEWIQQDFKS
>NC_019678.1|WP_015118468.1|2947646_2948177_-|hypothetical-protein
MKSNLKVLLLSLGLLLSSISTISAVTAQTSDRASAKNSLSFKQYELITASAKQVKNKELKAFFGSQYDYWDARVLANYWGQSVEEAKARIGRKIIWGKSDVAILEQFLVDARIQALQKMQSPNPSLELYSDSKYKYDDAQKLAAVWGDSSPWDAKIRIEKNLILGQPEVIEQALGK
>NC_019678.1|WP_015118467.1|2946416_2947529_-|amidoligase
MSQINWKIGCEIELLAPKGLSRKDLAESIAQLHHGSVRRIFYPQSEPSKVPGKPLFHNLTLGFEVVNKKGHLIAKCVDDLTLQDDLNKSHPSKPRWYRIVSDDTRFLQLIIAQANPEKSKAEVLKPIADLFGTVTEEGSGGMVRVADNTGLPIAIAAPLPGERERPCELITPPISTNHLEKLEVILHRARLLNFNIPVEGATHLHFDAVPLCSANVFANLVNIFHARGENLKRLVGTNPYCRRLGSWDIALFKLVNESGFRQLSWEQAVSKIAKLELSKYCDFNIKNLIHPIPDKFTFEARIFPAWLYAKPIVEAAALFEAILYYSINTSYISPHLPIKWELQSVKEFIKLLPISENFREIWLSRAENIS
>NC_019678.1|WP_015118466.1|2943472_2946001_-|NTP-transferase-domain-containing-protein
MRAVLMAGGSGTRLRPLTCDLPKPMVPILNRPIAEHIINLLKRHNITEIIATLHYLPDTMRDYFQDGSDFGVQMTYAVEEDQPLGTAGCVKNIAELLDDTFLVISGDSITDFDLTAAIKYHKEKKSKATLILTRVPNPIEFGVVITDQEGSIKRFLEKPSTSEIFSDTVNTGAYILEPEVLQYLPENQESDFSKELFPLLLEKGEPMYGYIASGYWCDVGHLDAYREAQYDVLNHKVKADFPYKEVAPGLWVGQNTHIESSAVIETPALIGDNCRIGNRVHIEAGTVIGDNVTIGSDANLKRPIVWNGAILGDEAQLSACVISRGTRVDRRAHVLEAAVVGSLSTVGEEAQISPSVRVWPSKKIESGAILNINLIWGNTAQRNLFGQRGVQGLANIDITPEFAVKLGAAYGSTLKPGSEVTVSRDQRNVSRMATRSLIAGLMSVGVEIQNLDATALPIARTIIPNMKVAGGIHVRVHPNRPDYLLIEFMDNKGINIPKAKEKKIEGAYFKEDMRRAQIHEIGNVAYPAQLVDRYCNAFENLLNIDTIRHSRAKVVIDYVYGVSGAVLPQMLDQFGADAVVLNASLNKIAPSETDREALLTQLGHVVEALKANFGVQVTANGEQMILVDESGIPIRGEMLTALMVDMILTANPRGSVVVPVHTSSAVEQIARRHDGKVIRTKANPTALMEACQKNPNVVLGGSGDTGFIVPELHPGFDSMFCIAKLIEMLTIQERSLTTVRSELPRVIHKTYTTRCPWTVKGALMRHLVETHPQEQLELIDGVKICQPYEDSWVLVLPDASEPLVHLYVNSNDRDWVDESLRKYRARVQEFVETEQEQVVVEV
>NC_019678.1|WP_015118465.1|2942027_2943353_+|ABC-transporter-ATP-binding-protein
MAQVVLEDIYKSFPPRKSEGVISKSAHRNESVNVLRRISLTVEDGEFMVLVGPSGCGKSTLLRLIAGLENVTGGNIWVGNRAVNQLQPSQRNIAMVFQNYALYPHMNVYENIAFGLRLQAGRAEREGERERGREGEKLLTKVSKIAEDLLVASTKKLPKGLRYVSDKERIVNERVINVAKLLQIEKLLNRYPKELSGGQRQRVALGRAIARNPQVFLMDEPLSNLDAKLRSQTRAEIVKLQRQLGITTIYVTHDQTEAMTMGDRVAILNRGQIMQIAPPLEIYNRPANRFVAEFIGSPAMNFIEVKFQSPCLITKGDFRLTLPENWSSALKKYNGRTLILGVRPENWNLSLPATKNLPAQVEWTENLGNDSYLAVKLIETKFEKDYLISDDLQVRVSPERLVNRGGKVWLSLNPEKIHFFDPETELAIFPKSNSPSLPFEK
>NC_019678.1|WP_015118464.1|2941411_2941627_-|hypothetical-protein
MYSTKELTKYKDYVIQPYYHSHQAPDKRWGYRIWKGYELMCVNENGCESSKKAVIAAIQEIDKGFLCDLCF
>NC_019678.1|WP_015118463.1|2940100_2940649_-|single-stranded-DNA-binding-protein
MNSCVLMAEIIKEPELRYKADNQLEITEMLVQFPGQRENDPPANLKVVGFGNLAKEIQQNYHEGDRVILIGRLSMNTIERPEGFKEKRAEMTVQQIHHLDSANENSFMQSPATQAIPVATTQTPSVNTPPPVAATTPKRNTVNAVPAQNAPQPEPVSQATSYEPSTYPAMVEEDIPEDDIPF
>NC_019678.1|WP_015118462.1|2937831_2939700_-|ABC-transporter-ATP-binding-protein
MRETVLDVRNLQVEFSDDGNVVKAVNGISFQLHRGETLGIVGESGSGKSVTSLAVMGLLQNPGRISSGEIWFRPQENGEALNLVDLPPKQIQLYRGGDIAMIFQEPMTSLNPVYNIGFQLTEAILRHQNITSAQARQNAIDSLQEVKLLPSDEQIRQNLIETSPKALNEAELPQLVQQHKEAILERFPHQLSGGQLQRVMIAMAISCNPLLLIADEPTTALDVTVQATIIDLLGELQQKRDMAMIFITHDLGLIAEIADKVAVMYKGKVVEQGDAGQIFTNPQHPYTKGLLACRPTLDSHPQKLLTVSDYMNVETTATGDVEITAKEPAEPLQVTSDEIAQRIATLEQQQPLLQIRNLKVGYPVKGMFGGTKRHFMAVNNVSFDVKKGETLGLVGESGCGKTTLGRSLLRLVEPLSGEILFEGRDITKLAGKPLQKLRREMQIVFQNPFSALNSRMKVGDAVMEPLVIHSIGKNKKEKQQRAAYLLERVGLSESAMNRYPHQFSGGQRQRICIARSLALNPKFIICDESVSALDVSVQAQVLNLLKELQEEFELTYIFISHDLSVVKFISDRILVMNRGEIVETGNAQEIYREPKEEYTQKLIASIPTGSPERMRNQQSVSN
>NC_019678.1|WP_015118461.1|2936494_2937184_-|hypothetical-protein
MVNRKYKRAVGTFASREDAEKALYKLRDSNFSMDKVSLLAKNPDGNEKIAGTQVKNERGENEAQEGAGIGATTGTVLGGLGGLLLGLEELLIPGIGPFLAAGTIATTLAGAGLGAATGGIIGALTGMAIPEEDARMYEDRINNGYYLLIVDGYEDEIDRAGSILSSHNIGNWKVFDAELPEGATVNPTPATPVVEKEVDVVNRKEVVDRKTVIDRDVVEVVDKRDNTIS
>NC_019678.1|WP_015118471.1|2950688_2952245_-|DNA-repair-protein-RadA
MPKPKTYYVCSECGGETPQWFGRCPACGTYNSLEEEIAVTNSTDVPSRGVGAWHSQMSKKKTANKPAKPRASLKLDQISDRQVERWSSGYGELDRVLGGGVVPGSMVLIGGDPGIGKSTLLLQVSNQLSQNYRVLYISGEESGQQVKLRGSRLGVAHQEHQEANGNGAVAVVKTTEDSDEKNQPTKTDSDLYVLPETDLEEILKEIESLRPNLAVIDSIQTVFFPALTSAPGSVAQVRECTAALMKVAKHEDITMLIVGHVTKEGAIAGPKVLEHLVDTVLYFEGDRFASHRLLRTVKNRFGATHEIGIFEMVSHGLREVPNPSELFLGSRDDPAPGTAIVVACEGTRPIVVELQALVSPTSYTSPRRACTGVDYSRLVQILAVLEKRVGIPMSKLDSYVASAGGLSVEEPAVDLGVAIAIVASFRDRIVDSGTVLIGEVGLGGQVRPVSQMELRLKEAAKLGFQRAIVPKGQKFPELDIEILPVSKVIDAIIAAIPQQTLTDEDLEMDDIDMEEMEE
>NC_019678.1|WP_015118472.1|2952425_2953154_+|response-regulator-transcription-factor
MESHKEKILVVDDEASIRRILETRLSMIGYDVVTAGDGEEALDTFRKAIPDLVVLDVMMPKLDGYGVCQELRKESDVPIIMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVLRRVDKTSASGIPSSGVIHVSTIKIDTNKRQVYKGDERIRLTGMEFNLLELLVSRSGEAFSRSEILQEVWGYTPERHVDTRVVDVHISRLRAKLEDDPSNPELILTARGTGYLFQRIIEPGDE
>NC_019678.1|WP_015118473.1|2953342_2953978_+|cofactor-assembly-of-complex-C-subunit-B
MANPDPNRFLRRLPIVVGGLGAVLLLINRLQSPELTESQARADVLGVILSAVLILTGLIWQQVQPRTPDTVELVGEKVFFLAEDLSDAVKTELAWASHLLLTNTVTRCVVVYYQGKVLLRRGILGEKSDVTPGAILKRVLEKHKPVYLVDLKVYPGRVEFDYLPGNTQGVICQPIGEEGVLILGAHAPRSYTKQDENWIAGIADKLAVTLK
>NC_019678.1|WP_015118474.1|2954114_2954636_+|DUF456-family-protein
MQIIYGLIIVLMLAGVIGAVVPGIPGTSLILLGIIIWGFIKGSFAAISIPLIVTGIVLLLSMGIDFLAAYWGAKKAGASKWGQIGSMIGLAVAFFGLLPPFLVVGGPIIGIFIGPLLGAIIGELIYRRNLVVAVKAGVGIVVGSLIGNIIQGCLALAAVIFFVFTTYTQVFGV
>NC_019678.1|WP_015118475.1|2954884_2955640_-|PEP-CTERM-sorting-domain-containing-protein
MRKFNVIAGILGLGLGFAAAAPAAHAASFIPQQEGEIKLTNLETLDPNQTISTSGLGFSVTSLEFDDAEAPEIEYGLSRLFVDDAATANNYGDGFIKFSSAGNDAGTNAGAGEFWLRAAAIQKNGVASEGGRLEVGRFLFEFERELEEITIDFFDVESLGSGILQVNGQSVTDKILADGLGDGNTQSLTLNNVNSLVLQLGNTNGSGSGDGVLISGVEAVKSVPEPTTTFSLGALAVAGMFGVKKRKNLKK
>NC_019678.1|WP_015118476.1|2956183_2956993_-|PEP-CTERM-sorting-domain-containing-protein
MKNIKKLVKTLAAVSTIGLGFATVSVSQAQAASLVPQIEGEIETNLGCLDPSNCIDTADLDFGYSVTSLKYDFDGKGPQFVESRLFSDDRSTRNDGTNGTFDLTQFGITFLDTDEGTNPNAGTNWFRAVAYEEGSTTPFEDGRLEVGRFKFDFNGKTANEVRLDFFDVEDGGFSGILEVNGQELSGQMLADMLLPAGPDSNIQTLVLKNVNDFVVQMGNPGPDSVFSNTGDGVSLEVKIPESENIIGLSALAVAGVITLKRRKRASQKA
>NC_019678.1|WP_015118476.1|2957883_2958693_-|PEP-CTERM-sorting-domain-containing-protein
MKNIKKLVKTLAAVSTIGLGFATVSVSQAQAASLVPQIEGEIETNLGCLDPSNCIDTADLDFGYSVTSLKYDFDGKGPQFVESRLFSDDRSTRNDGTNGTFDLTQFGITFLDTDEGTNPNAGTNWFRAVAYEEGSTTPFEDGRLEVGRFKFDFNGKTANEVRLDFFDVEDGGFSGILEVNGQELSGQMLADMLLPAGPDSNIQTLVLKNVNDFVVQMGNPGPDSVFSNTGDGVSLEVKIPESENIIGLSALAVAGVITLKRRKRASQKA
>NC_019678.1|WP_015118477.1|2959513_2960272_-|HEAT-repeat-domain-containing-protein
MYDADDRYLLDVEAELESPLDKMEPLSAESEAEKPSPEAMLALLENPQPQQKMLAARAFCDIEDARATPHLIRLLTDICPLVRVSAAYGIGRNPSPDAVEPLIHQYNQDWNGHVRKGVVWALGNCRDIRCLATLADALRTDISAVRLWAASSFAQMAEVGYEAVVGAMPPLIEGLVKDSVPAVRSNCAWSIGQLCKELPSNIVYATAIDALIQAFAEDNDLGVREDTKAALLGVGDPRGLQLIETLEQEGWF
>NC_019678.1|WP_083894125.1|2960403_2960820_-|GNAT-family-N-acetyltransferase
MQRTYQDMFPRQDFSHLSQTVEQYLSTETPLWWVEYSAEKQEQLDIFPTRPIACLWMGNAIDQISGLRHTHIFLLYVNPQHRRKGIGTALMQQAENSAKERGDTQIALQVFQTNEPAINLYNQLGYQTQSLWMVKPLQ
>NC_019678.1|WP_015118479.1|2960914_2961136_-|hypothetical-protein
MAILRQYIAPLIAVLIFSLALVAVSARIFLPSDMAAPAPIEEDAGVGTWQTGVASEFASLMSPSLEDKSNSRV

Crispr_ID: NC_019678_11

• CRISPR_ID: NC_019678_11
• CRISPR_location: 3020877-3021036
• CRISPR_type: Unclear
• Repeat_type: A:N
• Spacer_info: 2 spacers
• Cas_protein_info: cas5,cas7,cas8b3,cas6,RT

Consensus repeat of NC_019678_11

Consensus_repeat	Method
CTGATATCGATTTGCTTTTAAGCACTTT	CRISPRCasFinder

spacers of NC_019678_11

>11.1|3020905|38|NC_019678|CRISPRCasFinder
TTTTGTTGTTCTCAAAGGGTTTCAGGTTTTGAGTGGCA
>11.2|3020971|38|NC_019678|CRISPRCasFinder
ATTATCGGTTTAGTAAAGGTTTCAAGTTGTGGAATGGG

CRISPR arrays and Neighbor proteins around NC_019678_11

CRISPR arrays

The CRISPR arrays of NC_019678_11

>merge|NC_019678|11|3020877-3021036|CRISPRCasFinder
CTGATATCGATTTGCTTTTAAGCACTTTTTTTGTTGTTCTCAAAGGGTTTCAGGTTTTGAGTGGCACTGATATCGGTTTGCTTTTAAGCACTTTATTATCGGTTTAGTAAAGGTTTCAAGTTGTGGAATGGGGTGATATCGATTTGCGTTAAAAATAATT

>NC_019678|11|10|3020877-3021036|CRISPRCasFinder
CTGATATCGATTTGCTTTTAAGCACTTT	TTTTGTTGTTCTCAAAGGGTTTCAGGTTTTGAGTGGCA
CTGATATCGGTTTGCTTTTAAGCACTTT	ATTATCGGTTTAGTAAAGGTTTCAAGTTGTGGAATGGG
GTGATATCGATTTGCGTTAAAAATAATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015118519.1|3006015_3006534_+|phosphoribosyltransferase	unknown	unknown	gnl|CDD|225145
NC_019678.1|WP_015118530.1|3022873_3023758_-|restriction-endonuclease-subunit-S	unknown	unknown	gnl|CDD|341153
NC_019678.1|WP_015118524.1|3013771_3015349_+|type-I-MYXAN-CRISPR-associated-Cas8a1/Cmx1	cas8b3	cd09713_cas8b3_CAS-I-B	gnl|CDD|187844
NC_019678.1|WP_015118521.1|3007671_3008496_+|D-alanyl-D-alanine-carboxypeptidase-family-protein	unknown	unknown	gnl|CDD|367124
NC_019678.1|WP_015118522.1|3012121_3012688_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_019678.1|WP_044290893.1|3008783_3009767_+|hypothetical-protein	unknown	unknown	gnl|CDD|366375
NC_019678.1|WP_015118533.1|3026967_3028554_-|RNA-dependent-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209
NC_019678.1|WP_015118529.1|3021631_3022843_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015118534.1|3029712_3029904_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_157229407.1|3015329_3016286_+|CRISPR-associated-protein	cas7	cd09687_cas7_CAS-I-B	gnl|CDD|187818
NC_019678.1|WP_015118536.1|3030949_3032059_+|Holliday-junction-branch-migration-DNA-helicase-RuvB	unknown	unknown	gnl|CDD|234619
NC_019678.1|WP_015118526.1|3016291_3016930_+|type-I-MYXAN-CRISPR-associated-protein-Cas5/Cmx5/DevS	cas5	cd09688_cas5_CAS-I-B	gnl|CDD|187819
NC_019678.1|WP_044291764.1|3028814_3029057_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_044291757.1|3013106_3013775_+|type-I-MYXAN-CRISPR-associated-protein-Cas6/Cmx6	cas6	cd09703_cas6_CAS-I:CAS-III	gnl|CDD|370559
NC_019678.1|WP_015118532.1|3024984_3025974_-|TniQ-family-protein	unknown	unknown	gnl|CDD|377670
NC_019678.1|WP_015118535.1|3030009_3030777_-|imidazole-glycerol-phosphate-synthase-subunit-HisF	unknown	unknown	gnl|CDD|234996
NC_019678.1|WP_015118520.1|3006651_3007572_-|AEC-family-transporter	unknown	unknown	gnl|CDD|223751
NC_019678.1|WP_044291766.1|3032513_3033323_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_019678.1|WP_044290894.1|3026244_3026868_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NC_019678.1|WP_083894060.1|3009738_3012066_+|WD40-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|238121

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019678.1|WP_157229407.1|3015329_3016286_+|CRISPR-associated-protein	cas7	cd09687_cas7_CAS-I-B	2.8e-19	64.1	0.4
NC_019678.1|WP_015118526.1|3016291_3016930_+|type-I-MYXAN-CRISPR-associated-protein-Cas5/Cmx5/DevS	cas5	cd09688_cas5_CAS-I-B	6e-72	235.9	0.0
NC_019678.1|WP_015118524.1|3013771_3015349_+|type-I-MYXAN-CRISPR-associated-Cas8a1/Cmx1	cas8b3	cd09713_cas8b3_CAS-I-B	7.9e-77	252.7	2.2
NC_019678.1|WP_044291757.1|3013106_3013775_+|type-I-MYXAN-CRISPR-associated-protein-Cas6/Cmx6	cas6	cd09703_cas6_CAS-I:CAS-III	2.7e-60	198.4	0.0
NC_019678.1|WP_015118533.1|3026967_3028554_-|RNA-dependent-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	2.7e-36	119.9	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015118519.1|3006015_3006534_+|phosphoribosyltransferase	gnl|CDD|225145	COG2236, COG2236, Predicted phosphoribosyltransferases [General function prediction only].	1.2385e-35
NC_019678.1|WP_015118524.1|3013771_3015349_+|type-I-MYXAN-CRISPR-associated-Cas8a1/Cmx1	gnl|CDD|187844	cd09713, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-C subtype; also known as Csx13_N family.	1.63067e-68
NC_019678.1|WP_015118521.1|3007671_3008496_+|D-alanyl-D-alanine-carboxypeptidase-family-protein	gnl|CDD|367124	pfam02557, VanY, D-alanyl-D-alanine carboxypeptidase.	2.65141e-60
NC_019678.1|WP_015118522.1|3012121_3012688_-|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	2.12848e-29
NC_019678.1|WP_044290893.1|3008783_3009767_+|hypothetical-protein	gnl|CDD|366375	pfam00931, NB-ARC, NB-ARC domain.	3.39175e-26
NC_019678.1|WP_015118533.1|3026967_3028554_-|RNA-dependent-DNA-polymerase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	2.82211e-92
NC_019678.1|WP_015118530.1|3022873_3023758_-|restriction-endonuclease-subunit-S	gnl|CDD|341153	cd17264, RMtype1_S_Eco3763I-TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to Escherichia coli O69:H11 07-3763 S subunit (S.Eco3763I) TRD2-CR2. Escherichia coli O69:H11 07-3763 S subunit (S.Eco3763I) recognizes 5'... TACNNNNNNNRTRTC ... 3'. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	2.84189e-101
NC_019678.1|WP_157229407.1|3015329_3016286_+|CRISPR-associated-protein	gnl|CDD|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	1.135e-14
NC_019678.1|WP_015118536.1|3030949_3032059_+|Holliday-junction-branch-migration-DNA-helicase-RuvB	gnl|CDD|234619	PRK00080, ruvB, Holliday junction branch migration DNA helicase RuvB.	0
NC_019678.1|WP_015118526.1|3016291_3016930_+|type-I-MYXAN-CRISPR-associated-protein-Cas5/Cmx5/DevS	gnl|CDD|187819	cd09688, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	1.19555e-80
NC_019678.1|WP_044291757.1|3013106_3013775_+|type-I-MYXAN-CRISPR-associated-protein-Cas6/Cmx6	gnl|CDD|370559	pfam09559, Cas6, Cas6 Crispr. The Cas6 Crispr family of proteins averaging 140 residues are characterized by having a GhGxxxxxGhG motif, where h indicates a hydrophobic residue, at the C-terminus. The CRISPR-Cas system is possibly a mechanism of defense against invading pathogens and plasmids that functions analogously to the RNA interference (RNAi) systems in eukaryotes.	5.88473e-90
NC_019678.1|WP_015118532.1|3024984_3025974_-|TniQ-family-protein	gnl|CDD|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	9.24845e-20
NC_019678.1|WP_015118535.1|3030009_3030777_-|imidazole-glycerol-phosphate-synthase-subunit-HisF	gnl|CDD|234996	PRK02083, PRK02083, imidazole glycerol phosphate synthase subunit HisF; Provisional.	4.91989e-178
NC_019678.1|WP_015118520.1|3006651_3007572_-|AEC-family-transporter	gnl|CDD|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	4.96239e-36
NC_019678.1|WP_044291766.1|3032513_3033323_+|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.03173e-20
NC_019678.1|WP_044290894.1|3026244_3026868_+|TetR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	0.000229853
NC_019678.1|WP_083894060.1|3009738_3012066_+|WD40-repeat-domain-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	2.4968e-112

Protein sequences

>NC_019678.1|WP_015118526.1|3016291_3016930_+|type-I-MYXAN-CRISPR-associated-protein-Cas5/Cmx5/DevS
MVAPLILYLDVPFATFRESHAREMGKTYPVPPPATVYGMLLSLVGETDVYRHCGVELAIAMLSSPKKSRILRKMRRFKNADFSHPENVIPGYQEVLSNLKCLIWVRSDGEKIQPSLRDRIKLAFEHPELVRRFGCLFLGESDQLIKKIKLVSEDYLGEVRHWVIRDNRGGLTLPYWVDHVGSRNTRFLRYRIEEMDRLSPPNLAWTMIQSPI
>NC_019678.1|WP_157229407.1|3015329_3016286_+|CRISPR-associated-protein
MSQKKNDNNIPNYYLYGTVLTRYGLASLNHDISRGNKTILQKGYWNGKIHSFVGSSAIRWALRFYLQKQGYLVNRVWDEDEHINRLTSEDFDPEQFYDDDIFGFALLESAKTEEETSTTKRKKKKTKLSTPNQRLGALGMNMAVSLTPYDGAVKLGAKSGKKKDSTSLHFTEYHATRYQYYFAINVTHLKDFSRILPLIDGIMNLPKVGGSSNVFNYPFFPDSLVFQWTNNFASYVSYCFEYCEPKSKEVKLTKEFIDEVECGQIDPGQLWIGGTIVKDLQQLDNFDNSPFNKVNINRNRNELIEALKTVIKRDLGLE
>NC_019678.1|WP_015118524.1|3013771_3015349_+|type-I-MYXAN-CRISPR-associated-Cas8a1/Cmx1
MIATQPKISLSLDAADTTIIHRAGMTGLYMTLKRLEKQYPSSHQRGGYISWNLTADTIELSWEGSDLVALSWLIKESFKLDDTGLIHLAGLENDAIDLIQKIHIHEGMRAVFLRHNKFYKAGELVDTELTVKDKKVEYQYQSLTWYAHQTFAEKLCNIDTQQLRRDYIQITSWLYLGGIVRHAKTQNITKLEEKLEYAFALLFVPVICHYCLFHIPSEDLKEKKPHRYLVVIPEIKDFEDASQRRWRLQQLETKQFHVSNLGEAGLIYYSLDDIHTEADYYQACQVWLYEKMNKSSRQRTLMGIEEIKIYKNTLTTYQQVQKYFKTNYQKIKPKQVFVKVNPIRSLIADNLVKGNHWWSKFWEKLVIEDSKEYLFNQLFFNREGLVIMAENSEEDKQYLIFIKVFQQAMKGNFAKLYAKTEEGKNPPIKKKVERLRAELNCCYDELSFKEYLSDFLVRGGLNKYFNHHQEEIALLIKKSSWQELRIWALLAIASYKPKDKPTNSDDHSLTNNQQLEEMNDESEEE
>NC_019678.1|WP_044291757.1|3013106_3013775_+|type-I-MYXAN-CRISPR-associated-protein-Cas6/Cmx6
MAALLIPSEEYVDLTFKLRGAPIPLDNGYVIYSALSRICPSLHELKSIGIHPIAGIPTRNNLLEIAAQSRLKIRIHHQQIPLLYPYLAGQAFHIGKNSYQLDIPDYKPLISSESVYSRLVVIKGFQDPSNFIEAVQRQLDNLEIQGKIELLTRQDGTPQRRQLTISKEGKQFKVRGFGVKVSELNPEDSLTLQEHGIGGKRKMMCGIFVPATRNKEEKETIT
>NC_019678.1|WP_015118522.1|3012121_3012688_-|Uma2-family-endonuclease
MTVQLLRRKFTVEQFHKMAAVGILNEDDRVELIRGEIIEMAAIGTKHACCVRRLDKVLHRKLGDEVIISVQNPIGLDDSSQPQPDVALLKPREDDYLSAHPQPKDVFLVIEVADTTIKYDREVKTPLYAEESVVEVWLVDINSECVEVYREPATDGYQKVDKLVRGESLVIQAFDDVNINVNEILGNN
>NC_019678.1|WP_083894060.1|3009738_3012066_+|WD40-repeat-domain-containing-protein
MYCRSCSRADLDKIQQQFPDYPYPDLLKAIQVSVETLEADTKEKYFDFAIFSEDTAIPEQVLQIFWQAEGLDEYDTQDVVDELANKSLVSTDEDGKLRLHDLQLDYLRKQTEDLSTLHNRFLQAYSQKYPDGWHTLENDGYIYQYLSYHFQQAQREDELQQLLLDFRWLKAKLKNTNINALIADYNLILSENNFDRQSQSPQDKSLQLVKGALQLSAHILAGDKNQLPGQLFGRLLSFQNPEIQHLLQQAKNNQTSLWLRPFVPSLTPPGKELIATFQGHSDSVYAVAYAPDGKRAISASYDNTLKLWDLQTGEIEHTFQGHSDSVNAVAYAPDGKQAISASDDNTLKLWNLQTGEIEHTFQGHSDSVYAVAYAPDGKQAISASDDKTLKLWNLQTGEIEHSFQGHSNSVNAVAYAPDGKRAISASHDQTLKLWNLQTGEIEHTFQGHSNSVNAVAYAPDGKRAISASYDKTLKLWNLQTGEIEHTFQGHSNWVYAVAYAPDGKRAISASYDKTLKLWNLQTGEIEHTFQGHSDSVYAVAYAPDGKQAISASDDQTLKLWNLQTGEIEHTFQGHSDWVVAVAYAPDGKQAISASDDKTLKLWNLQTGEIEHSFQGHSNWVNAVAYAPDGKQAISASDDKTLKLWNLQTGEIEHSFQGHSNWVNAVAYAPDGKRAISASDDKTLKLWNLQTGEIEHSFQGHSNWVNAVAYAPDGKRAISASGDKTLKLWNLETKEEEDTFTGEAFMVSCAVAPDGLTIVAGDVEGRVHFLRLEEGN
>NC_019678.1|WP_044290893.1|3008783_3009767_+|hypothetical-protein
MNNNTIKYSGRVKTIICKRLTNDWQDLADYFDIQLHEREGFRSGRQAHGVWEWLEQRDRIGELESALNDIGRDDLVEELKKKLVDGESTSLCLAKLFNVPKLPDNFLPRDEQLQPLKQKVLSHTNQPVGITSTTRRVGLQGMGGIGKTVLATALARDEDIRKKFFDGIFWITLGQRPKLLDWQLYLSETLGDNQATFTEISFGKAKLKQLFADKSCLLILDDIWNLNHATTFDVLGEKCQMLVTTRDASIITSFGAVRHELAVLSQEQSLTLLADWAGYKDNTLLPPEANQVVEECGNLPLALSMVGAMLRGKPNLWGNVLQKLLPC
>NC_019678.1|WP_015118521.1|3007671_3008496_+|D-alanyl-D-alanine-carboxypeptidase-family-protein
MNNEFYEEAQNSTPSEISEDIPQALRDTPDAAPKLGLSSSFVAIAGVMGFVLLAAISGLIFYVATPKNTAKQQPSPTSSASPNTLDSDSVNKKAEQQTLLGHLEYKEAPESEIVAVNVGGRRIKLRKSAGERFKQMAKDAQKAGVRLVPISGFRSVKEQEKLFIRVGAQRNQTPAQRASVSAPPGHSEHHTGYAVDIGDGAVPATNLSTKFEKTKAFKWLEANAPRYSFELSFPEGNSQGVSYEPWHWRFVGDRDSLETFYKGRDVKPIPTPES
>NC_019678.1|WP_015118520.1|3006651_3007572_-|AEC-family-transporter
MLENILELYFKLIATVSIGFLLGRWLPNTALNRLGKFLFWIGVPIGIVAFLRKADLSGAIWIAPAVAYAAMLLGAFFAIVVIKLQSYFTSTVLLQPTQGSLIISAMAGNTGFLGYPITLAVHGTQYFAWGLFYDLLGSLFVTWGFGTVIAARFSGSATNFLQISKVILINPALWSFGFGLLFRQIKIPPSAEFVLDKFAWIGVGLSLILMGMRLSKLNSWHNLPQAGISIAIKMLLVPLILGSIFRVVGLTGTPAQVIVIQAGMPPAFSTLIIAEIFNLDSDLAVTTVATGTIILLLTLPMWLIVF
>NC_019678.1|WP_015118519.1|3006015_3006534_+|phosphoribosyltransferase
MPDLYISWSDYHHKIEQLAAQIYQSGWEFNQIVCLARGGLRVGDILSRIYKQPLAILATSSYSGAGKQERGELTFSRHLTMTEEALGSRILLVDDLVDSGVTLKETIPWLKKNSHSKIEEIRSAVIWYKACSVIVPNYYADYLPDNPWIHQPFEGYEFTNPAELAEKVSQPC
>NC_019678.1|WP_015118529.1|3021631_3022843_+|hypothetical-protein
MSFLPEGTILGQLEIIEVYDFYDKPVLFSCKNKSGLIFIVIYVDDSDLAEIWLYAPISSSRFQNVVQGRVELRNIFIDTEDAFVYQVEIPYEEGMNVIIKSVNCDKIPDEYLPELGQVIQSKNNSADTNIETVSTEKRREIIDFVLQFPEQEITEAPVGDLGLILSSLQETIDAIGQIKLGKSESHIIPPEVKQKTQVVMSGVFSGSFGMRLEGTVYEEDSLGLEESFLGQCLKEFIQLINLGANKEELPAKLNVLKKKTAFKYTEFLTALTRIGITKLRIDWASPGQKVQMGEIEQETVFKVIDVIKNTKLRTETEICVNVKLTQINYSSKTITLQEIGSKKKYKCFIADSAMKDVETISRKVVYVATIQEYVIVSTVLNKEKHEYELLSLKLEAESENISA
>NC_019678.1|WP_015118530.1|3022873_3023758_-|restriction-endonuclease-subunit-S
MKQAERSLIPSMSVKHLAEITIPVPPLPEQKRIVTILDEAFEGIDRAIANTEKNLANSRELFKSYLQSVLTERGKGWVETTLGKVCQFENGDRGKNYPNREEYVKSGIPWINTGHIQPDGTLSHSEMNFITREKYESLRSGKIRPGDLVYCLRGATIGKTALVSPFTVGAVASSLVIIRPSDLLDSYFLYYFLTSSVGQRQIKLYDNGAAQPNLGAKNVAKYIILLPKLAEQKVIVQKLASLAAETQRLETTYRQKLAALNELKQSILQKAFTGELTGDTAKKVRKTAKGEIAA
>NC_019678.1|WP_015118532.1|3024984_3025974_-|TniQ-family-protein
MTIYLEHWNLKPPEIPQRSRLFSLEPVAVGTPYAESLSSYLHRLAQAHCLTSQKLVMGEIAPLILTQEDKSELLKKNVSHLLGNSDAKPAINGMREMTGRLVTVLEELTMRHDLRFLTLLSWKGMIYDKGLFRNHRAWCPCCLEERRQENKIIYEPLLWSFKDVEFCLIHKQRLIEECPHCGSHLPVITKLSSAGFCSRCYGWLGQEIKGEEEIEKYRVKIQGISELIALTPQLGYEPIPIELTRKLQLILLVFEQAIAKDLLLLGDLGRIMESLRIASKTNQNQPYHLVKLIIPVCEKAKISVYQLFGSDFRELGKILFENFGLELKL
>NC_019678.1|WP_044290894.1|3026244_3026868_+|TetR-family-transcriptional-regulator
MKKNELEQKIWIAKTIGELIAGIPYLNDSLSSNTIALNLSKWVEQIAEGNIAEFARQINIPRNTVWLWCKGKNSPSLKALTNVCYFLGVSVLSFLTEEANNLCISKKLFTTELESKSRKKSKPFNSEKVKSDLEALLTNDDSPVLSMEEVARRLGIDRRTIYKYFPDLCRAISARYINYQKDYHKKILEECCQEVRLVALKLHNQGK
>NC_019678.1|WP_015118533.1|3026967_3028554_-|RNA-dependent-DNA-polymerase
MIRHGKTASESWKSLPWKKFRANVFRLQRRVFKAVRVGDKRKARQLQKLILKSRAARFLAIRQVTQLNAGKKTAGIDGKKSLTFEERFALEELLKAKSSKWKHQKLRAIPIPKKDGTTTRLLKIPTLADRCWQCLAKYALEPAHEATFHKHSYGFRTGRSAHDAQKQVFQNLKSSSNGINKRILELDIEKCFDRINHSSIISNLIAPNRLKLGIFRCLKVGINPDFPEQGTCQGGVVSPLLANIALNGIEELHKYHTNKGRKIKATTPEKDINTACVRYADDMVFFLRPEDDEKEILDNISQFLAKRGLKVSEKKTKLTASTFGFDFLGWHFKVQQNGKFRSSPSEENFKAFRKKVKKIANNSNYGASEKAKKLAPIVRGWRQYHKFCKMDSARFNLYHIQHRAYKVFNQETKQDRLSSKKLLDKAFPTVCYSENRHIKVKGNKSPFDGDLVYWSKRNSKLYDGITSRLLKKQNHTCGYCGHKLTSEEKVNLHHCDGNHSNWKDYNLTVVHESCHDYIHMKQKGKELR
>NC_019678.1|WP_044291764.1|3028814_3029057_-|hypothetical-protein
MYNCSFDVGEPSSIERQVLPLRRQVTPYLPTVTILGIMEAEAGNRTQSVVKQAGINTGVNGKMTLGKQVLEKCLRNQATT
>NC_019678.1|WP_015118534.1|3029712_3029904_-|hypothetical-protein
MLIPILVFDVALVAWSLHLMERAVEDKEFSLMLAGMLVALAAAAMMVVYFLMGHCMSYLLQAS
>NC_019678.1|WP_015118535.1|3030009_3030777_-|imidazole-glycerol-phosphate-synthase-subunit-HisF
MLAKRILPCLDVKAGRVVKGVNFVDLKDAGDPVELAKVYDEAGADEIVFLDITATHEDRGTIIDVVHRTAEQVFIPLTVGGGIQTLENVKELLRAGADKVSINSTAVRNPDFINQASKRFGNQCIVVAIDAKRRSNTENPGWDVYVRGGRENTGLDAIDWAKEVEKRGAGELLVTSMDADGTQAGYDIELTRTIAAKVGIPVIASGGAGNCEHIYSAVTEGQAEAALLASLLHYGQLSVAQIKNYLNDRKIPVRN
>NC_019678.1|WP_015118536.1|3030949_3032059_+|Holliday-junction-branch-migration-DNA-helicase-RuvB
MAIISSKKQPQPQEPDKEPTHLKKAAKQKADEKLLQPEAAIDEQDSNEVGIRPQQFADYIGQKDLKDVLDIAIKAAKSRGEVLDHLLLYGPPGLGKTTMAMILASEMGVNYKITSAPALERPRDIMGLLVNLKPGDIIFIDEIHRLSRMTEEILYPAMEDYRLDITVGKGSSARTRSIPLAKFTLVGATTRVGALSSPLRDRFGLVQKLRFYEVEELSQIVLRTADVLKTDVSKDGALEIARRARGTPRIANRLLKRVRDYAEVKSSGTINETVAAEALQLFQVDPCGLDWTDRTMLSVIVEQFNGGPVGLDTIAAASGEDTQTIEEVYEPYLMQIGYLQRTPRGRVATPAAYKHLGFKPPSEQLSLLS
>NC_019678.1|WP_044291766.1|3032513_3033323_+|tetratricopeptide-repeat-protein
MMKLLGILLSVLLLFSWVEPVFALTNQASNLTKEELKQQDQLANKAFAATNKGDFAVAEEYWTEILEKFPENAAVWSNRGNSRVSQNKLEEALVDFNKSIELAPNVTDPYLNRGTALEGLGKWDEAIADYNHVLELDPDDAMAYNNRGNAEAGLKKWQEAIADYRKSAEIAPNFAFARANYVLALYEIGEEDKAIREMKNIIRKYPQFPDVRASLTAALWAKGEKGEAESNWVAAYGLDRRYKDIDWVKNVRRWPDRMVAALDKFLKLQ

Crispr_ID: NC_019678_12

• CRISPR_ID: NC_019678_12
• CRISPR_location: 3045215-3045319
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 1 spacers

Consensus repeat of NC_019678_12

Consensus_repeat	Method
GGCGTTGCTGATTAAAAGTATGATTT	CRISPRCasFinder

spacers of NC_019678_12

>12.1|3045241|53|NC_019678|CRISPRCasFinder
GCCCCCCAAACCCCAATTCTGGGGAAGAAAATCATTTATTTAATCTCTTTTTT

CRISPR arrays and Neighbor proteins around NC_019678_12

CRISPR arrays

The CRISPR arrays of NC_019678_12

>merge|NC_019678|12|3045215-3045319|CRISPRCasFinder
GGCGTTGCTGATTAAAAGTATGATTTGCCCCCCAAACCCCAATTCTGGGGAAGAAAATCATTTATTTAATCTCTTTTTTGGCGTTGCTGATTACAAGTATGATTT

>NC_019678|12|11|3045215-3045319|CRISPRCasFinder
GGCGTTGCTGATTAAAAGTATGATTT	GCCCCCCAAACCCCAATTCTGGGGAAGAAAATCATTTATTTAATCTCTTTTTT
GGCGTTGCTGATTACAAGTATGATTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015118548.1|3043249_3044701_-|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl|CDD|214349
NC_019678.1|WP_015118539.1|3035097_3036396_-|hypothetical-protein	unknown	unknown	gnl|CDD|181765
NC_019678.1|WP_015118553.1|3051122_3052139_+|NAD-dependent-epimerase	unknown	unknown	gnl|CDD|187563
NC_019678.1|WP_015118545.1|3039813_3041364_+|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|225118
NC_019678.1|WP_015118557.1|3055362_3056031_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_019678.1|WP_044291768.1|3038314_3038926_+|hypothetical-protein	unknown	unknown	gnl|CDD|227672
NC_019678.1|WP_015118538.1|3033791_3035054_+|alpha-1,2-fucosyltransferase	unknown	unknown	gnl|CDD|211387
NC_019678.1|WP_015118550.1|3046272_3047514_+|glycosyl-transferase	unknown	unknown	gnl|CDD|227017
NC_019678.1|WP_015118552.1|3049663_3050818_+|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NC_019678.1|WP_015118554.1|3052253_3052622_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|381139
NC_019678.1|WP_015118551.1|3047694_3049572_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NC_019678.1|WP_015118555.1|3053386_3054271_-|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl|CDD|213022
NC_019678.1|WP_015118547.1|3042673_3043087_-|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl|CDD|214351
NC_019678.1|WP_015118543.1|3038971_3039316_+|hypothetical-protein	unknown	unknown	gnl|CDD|227726
NC_019678.1|WP_085977718.1|3036466_3037255_-|TIGR01548-family-HAD-type-hydrolase	unknown	unknown	gnl|CDD|273685
NC_019678.1|WP_015118544.1|3039332_3039674_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015118560.1|3058910_3059357_-|SRPBCC-family-protein	unknown	unknown	gnl|CDD|378454
NC_019678.1|WP_015118558.1|3056137_3057694_-|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_019678.1|WP_015118541.1|3037476_3037806_+|30S-ribosomal-protein-PSRP-3	unknown	unknown	gnl|CDD|235062
NC_019678.1|WP_015118559.1|3057936_3058761_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|225464

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015118548.1|3043249_3044701_-|F0F1-ATP-synthase-subunit-beta	gnl|CDD|214349	CHL00060, atpB, ATP synthase CF1 beta subunit.	0
NC_019678.1|WP_015118539.1|3035097_3036396_-|hypothetical-protein	gnl|CDD|181765	PRK09294, PRK09294, phthiocerol/phthiodiolone dimycocerosyl transferase.	1.84175e-17
NC_019678.1|WP_015118553.1|3051122_3052139_+|NAD-dependent-epimerase	gnl|CDD|187563	cd05253, UDP_GE_SDE_e, UDP glucuronic acid epimerase, extended (e) SDRs. This subgroup contains UDP-D-glucuronic acid 4-epimerase, an extended SDR, which catalyzes the conversion of UDP-alpha-D-glucuronic acid to UDP-alpha-D-galacturonic acid. This group has the SDR's canonical catalytic tetrad and the TGxxGxxG NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	0
NC_019678.1|WP_015118545.1|3039813_3041364_+|SpoIIE-family-protein-phosphatase	gnl|CDD|225118	COG2208, RsbU, Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription].	1.06517e-62
NC_019678.1|WP_015118557.1|3055362_3056031_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.30512e-82
NC_019678.1|WP_044291768.1|3038314_3038926_+|hypothetical-protein	gnl|CDD|227672	COG5381, COG5381, Uncharacterized protein conserved in bacteria [Function unknown].	3.43582e-35
NC_019678.1|WP_015118538.1|3033791_3035054_+|alpha-1,2-fucosyltransferase	gnl|CDD|211387	cd11301, Fut1_Fut2_like, Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.	8.08664e-37
NC_019678.1|WP_015118550.1|3046272_3047514_+|glycosyl-transferase	gnl|CDD|227017	COG4671, COG4671, Predicted glycosyl transferase [General function prediction only].	2.56656e-137
NC_019678.1|WP_015118552.1|3049663_3050818_+|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	2.66415e-54
NC_019678.1|WP_015118554.1|3052253_3052622_-|response-regulator-transcription-factor	gnl|CDD|381139	cd17624, REC_OmpR_PmrA-like, phosphoacceptor receiver (REC) domain of PmrA-like OmpR family response regulators. This subfamily contains various OmpR family response regulators including PmrA, BasR, QseB, tctD, and RssB, which are components of two-component regulatory systems (TCSs). The PmrA/PmrB TCS controls transcription of genes that are involved in lipopolysaccharide modification in the outer membrane of bacteria, increasing bacterial resistance to host-derived antimicrobial peptides. The BasS/BasR TCS functions as an iron- and zinc-sensing transcription regulator. The QseB/QseC TCS activates the flagella regulon by activating transcription of FlhDC. The RssA/RssB TCS regulates swarming behavior in Serratia marcescens. OmpR family DNA-binding response regulators contain N-terminal receiver (REC) and C-terminal DNA-binding winged helix-turn-helix effector domains. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	2.86154e-39
NC_019678.1|WP_015118541.1|3037476_3037806_+|30S-ribosomal-protein-PSRP-3	gnl|CDD|235062	PRK02724, PRK02724, 30S ribosomal protein PSRP-3.	8.87898e-66
NC_019678.1|WP_015118555.1|3053386_3054271_-|polysaccharide-deacetylase-family-protein	gnl|CDD|213022	cd10917, CE4_NodB_like_6s_7s, Catalytic NodB homology domain of rhizobial NodB-like proteins. This family belongs to the large and functionally diverse carbohydrate esterase 4 (CE4) superfamily, whose members show strong sequence similarity with some variability due to their distinct carbohydrate substrates. It includes many rhizobial NodB chitooligosaccharide N-deacetylase (EC 3.5.1.-)-like proteins, mainly from bacteria and eukaryotes, such as chitin deacetylases (EC 3.5.1.41), bacterial peptidoglycan N-acetylglucosamine deacetylases (EC 3.5.1.-), and acetylxylan esterases (EC 3.1.1.72), which catalyze the N- or O-deacetylation of substrates such as acetylated chitin, peptidoglycan, and acetylated xylan. All members of this family contain a catalytic NodB homology domain with the same overall topology and a deformed (beta/alpha)8 barrel fold with 6- or 7 strands. Their catalytic activity is dependent on the presence of a divalent cation, preferably cobalt or zinc, and they employ a conserved His-His-Asp zinc-binding triad closely associated with the conserved catalytic base (aspartic acid) and acid (histidine) to carry out acid/base catalysis. Several family members show diversity both in metal ion specificities and in the residues that coordinate the metal.	2.47611e-74
NC_019678.1|WP_015118547.1|3042673_3043087_-|F0F1-ATP-synthase-subunit-epsilon	gnl|CDD|214351	CHL00063, atpE, ATP synthase CF1 epsilon subunit.	4.39864e-60
NC_019678.1|WP_015118543.1|3038971_3039316_+|hypothetical-protein	gnl|CDD|227726	COG5439, COG5439, Uncharacterized conserved protein [Function unknown].	2.50055e-39
NC_019678.1|WP_085977718.1|3036466_3037255_-|TIGR01548-family-HAD-type-hydrolase	gnl|CDD|273685	TIGR01548, Imidazoleglycerol-phosphate_dehydratase, haloacid dehalogenase superfamily, subfamily IA hydrolase, TIGR01548. This model represents a small and phylogenetically curious clade of sequences. Sequences are found from Halobacterium (an archaeon), Nostoc and Synechococcus (cyanobacteria) and Phytophthora (a stramenophile eukaryote). These appear to be members of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases by general homology and the conservation of all of the recognized catalytic motifs. The variable domain is found in between motifs 1 and 2, indicating membership in subfamily I and phylogeny and prediction of the alpha helical nature of the variable domain (by PSI-PRED) indicate membership in subfamily IA. All but the Halobacterium sequence currently found are annotated as "Imidazoleglycerol-phosphate dehydratase", however, the source of the annotation could not be traced and significant homology could not be found between any of these sequences and known IGPD's.	3.10087e-69
NC_019678.1|WP_015118559.1|3057936_3058761_+|tetratricopeptide-repeat-protein	gnl|CDD|225464	COG2912, COG2912, Uncharacterized conserved protein [Function unknown].	7.04189e-71
NC_019678.1|WP_015118558.1|3056137_3057694_-|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.2867e-52
NC_019678.1|WP_015118551.1|3047694_3049572_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.99192e-166
NC_019678.1|WP_015118560.1|3058910_3059357_-|SRPBCC-family-protein	gnl|CDD|378454	pfam10604, Polyketide_cyc2, Polyketide cyclase / dehydrase and lipid transport. This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. It also includes other proteins of the START superfamily.	2.17393e-13

Protein sequences

>NC_019678.1|WP_015118548.1|3043249_3044701_-|F0F1-ATP-synthase-subunit-beta
MVSTAEKTNTGYITQIIGPVVDVKFPNGKMPAIYNALIVKGTNEAGQEMSVTCEVQQLLGDNQVRAVSMTSTDGLVRGMEASDTGAPISVPVGKATLGRIFNVLGEPVDNQGPVGTDETSPIHREAPKLTDLETKPSVFETGIKVVDLLTPYRRGGKIGLFGGAGVGKTVIMMELINNIATQHGGVSVFGGVGERTREGNDLYNEMIESKVINPDNLNDSKIALVYGQMNEPPGARMRVGLSALTMAEYFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTDVGALQERITSTNEGSITSIQAVYVPADDLTDPAPATTFAHLDGTTVLSRGLAAKGIYPAVDPLGSTSTMLQPNIVGEDHYQTARSVQSTLQRYKELQDIIAILGLDELSEDDRLIVARARKVERFLSQPFFVAEVFTGAPGKYVKLEDTIKGFQAILSGEFDELPEQAFYMVGSIDEAKAKAEKMKSK
>NC_019678.1|WP_015118547.1|3042673_3043087_-|F0F1-ATP-synthase-subunit-epsilon
MTLTVRVISPDKTVWDSKAEEVILPSTTGQLGILSGHAPMLSALDTGVMRVRADNNQNWVAIALSGGFAEVEEDEVTILVNAAEQGNSIDLEEARTAFNEAQTRLNQIAQGDRQGQIQATQSYKRARARFQAAGGMA
>NC_019678.1|WP_015118545.1|3039813_3041364_+|SpoIIE-family-protein-phosphatase
MKDANKKNFFQTIFSDKKYRPLLISAGLFLCFDLGVLIPNYVFSTLLKKDAVSINLAGRQRMLSQKMTKSLLEVKNQQEAGSSFKESREELKKAYELFDDALDGFGRGKSVQGADGEPVYLPVVDTEKKRAILDQALAIWTPYKEKLQPILKADESIQFKDLEAAVEYARENNLKLLSLMNQLTIESEQVAQTKTGYLQLIQLIGMTLALGNFFILLSRSFKRMQIADQEIETANAQILQLNERLQADNIRLKSELDATRRLQQMILPKSSELESVEGLDIAGYMEPADEVGGDYYDVLNLDGNVKIGIGDVTGHGLESGMLMLMVQTAVRTLQEVEETNPVRFMDILNRTIYKNIQRMDSGKNLTLSLIDYSDGELKLSGQHEEVILARSNGEVELLDTTDLGFPIGLDDEIADFVDEQKIKLDVGDVAVLFTDGITEAEDIHKNLYGIEKLCEVIKQNRHLSASEIKDAVIEDVRSHIGLQQVFDDITLLVLKQKDTGTSLNSLQSQSLATVGI
>NC_019678.1|WP_015118544.1|3039332_3039674_+|hypothetical-protein
MVSPENLSTDELLLKIKSLKYELEEVKQQKADLEIMIESIAEHSSELNNLYFKKNQELLLYIEQVKQLVAVTQNRLDGDSSDSEVLERIAARNDEIGEIAQVFLIIDKRFTAS
>NC_019678.1|WP_015118543.1|3038971_3039316_+|hypothetical-protein
MQVKGENYNVWYDNNNGAVNFDGALRLTGMQDYAPILKLLNEIASTEPPSMVLNLQRLEFLNSSGISMLSKFVIGMRKKKSVQIKILGSNNIAWQGKSLKNLQRLMPGLTLDLQ
>NC_019678.1|WP_044291768.1|3038314_3038926_+|hypothetical-protein
METLFNKDNLEKAQVFGDYVERPQQDEHLTLGFSPSAIPIKKRWRNNGLSADYIANYLATFFPIQASEPDAMDKLAEMKSAVSYIANELLENSMKYADATALYPITLHTQIENNKIRLFVDNSILASQAENFQLFIKELLNSDPDELFIRKLEENAEDENTSSSGLGFLTMINDYSAKLGWKFDIVQKDSPVMTVTTMVELAV
>NC_019678.1|WP_015118541.1|3037476_3037806_+|30S-ribosomal-protein-PSRP-3
MENQNQTQELLSKFILKILWLDDNVALAVDQIVGKGFSPLTKYFFWPRTDAWEELKNELESKHWIGEVERVELLNKATEVINYWQEEGRRRPMSEAQGKFPEVIFTGSN
>NC_019678.1|WP_085977718.1|3036466_3037255_-|TIGR01548-family-HAD-type-hydrolase
MPAIVVFDIDGVIRDVSGSYRRALADTVEHFTAQAYRPTADDIDRLKSEGVWNNDWEGSQELIYRYFETKAQSRQQLNLDYNSIVAFFQSRYRGTNPDNLTGYICDEPLLLQPSYLNQLTEARIRWGFFSGATRASATYVLQQRLNLQSPVLIAMEDAPGKPDPTGLFSTLELLQFGIDINNLPPVIYVGDTVADMYTVEKARNNQSNRTWIGVGVLPPHVQETAQKRDAYTESLKKAGATIVLSNVQELTPEQIQKLMQDL
>NC_019678.1|WP_015118539.1|3035097_3036396_-|hypothetical-protein
MLETRELTAHEQSMEILNNLAASFHIVTTSRVKGLLNEELLRQALDTTQERHPFLNARIVEKSNSFWFEPVAGKIPLLVVNKQHTQQWEEVVIEELNKKIDSDTNLLRVTLVRLEAENICYLITVIHHSISDASSSIQLHSELLTYCQNIVEGKANNQVNRLSQLPSIYQLIPKSFQGFTGAISNVFYLLNLKLRLSRYQPITIGFEKSLPIESRSCGMVHKKLDSELTRRLVEVCRQNQTTVQAALGAAMLFAVAQKNNYSQTESNYFSFRSSVNLRGRLQSKISNEHLGAMASAVVSFHNFQANDNFWDLARDIKQKLERGLARGDGFRQLLMFKTIMKYFMKKPYQSAVTAALTNIGRVNIPQNYGQFELEEISFVPAQSVFGGVFAAAVSTFRDKMLLNFMFSQPSISTETIENLADDMICIISDICN
>NC_019678.1|WP_015118538.1|3033791_3035054_+|alpha-1,2-fucosyltransferase
MTKDKYARKSETDRGFSVFKTFKKDADGINLLSANDATISNEPVISMSSLGDLGRFGNQLLQYAFLKVCAKKSNARMECSPWIGQTLFGLEDAPISRRLPLAVEESYYGPNLFDYIPEFIPYLEKLSHQNSFRIPGEEIIESNLVNVDLWGFFQVHTHYLQPYKEEIRSWFEPVSDLKSSLLDGLNILRSQGKTIVGVHIRRGDFYSVPMAGFTLVVPTKWWCQWLESIWDELENPVLFLCSDDLDNVIDDFKQFSPITYKDLNIELPERMKDLNIEFYIDFFLFSNCDIAGISNSIFSFAACMLNQQATKFVRPTWNFSQKFEEFEPWNSVPLLHIGDPIKPKSFKSFGDAIYTTRITQGIWGMLKFIFIYYPKNSLKTWVIRAYLGYQIQGLVGVFKSLLYTVGWRNVWKNHIQPSET
>NC_019678.1|WP_015118550.1|3046272_3047514_+|glycosyl-transferase
MKIMVYSHDAFGLGNIRRMLAICEHLLTEIPQLSILLLSGSPMLQGFRLPRGLDYIKLPCLNRGNTGEFAVKYLGIDIDKTLKMRSELILSAAVNFQPDLFLVDKKPLGIENELTTAVNYIHQNLPETKLVLLLREILNSPEKTIPEWQKSRYTEVIDKFYQLLLIVGSQQVFDFCKEYKLPHSVTDKTHFCGYIGRPQDCKINQNIREELQLEPLDKLVVVTPGGGEDGYELINTYLQGQELLKNSQYRIKSLVFCGPEMPQKQKQELCAMAVKYPNVEMREFTNDLMSYLSIANAVVSMGGYNTVCEIMSAAKPAIIVPRIQPSQEQLIRSQRMHDLGLLRSIHPQENTPQALMTQLFQILENPQVPKNIDLEGLPRITHHIRNLLADKMTPTQAEFVYPQSNPSQELLVS
>NC_019678.1|WP_015118551.1|3047694_3049572_+|ABC-transporter-ATP-binding-protein
MACQDSKKTKPKTTQNIKAALPGINQILRRFSPQIQKQRSLLIISFLGLMAEIGLHLLEPWPLKLIFDYILVEDFKTKISQLPLLSEFTPVTLVTIFCLSLIAIVGLRACAAYLGVYYMALAASNVLTEVRTELYSHIQRLSLSFHYKAKTGDLIARVTSDIDKIREVTVMALLPLIANSLTILGMIFVMFWLHWELATIALALFPLFIFSTYRLTKSIRGVVKSQRKREGTIAAAAAESLGAIKVVQALSLQDMLEASFANENRQSLQASVKVKKLSAGLERIVELLIGLATALVLWRGVHLVLGNHITPGDLLIFVNYFRIAFKPMRVLAKYVGQISKATASGERILDILDTVPDISDRRFAFDAPPIKGCIEFDNVSFGYDLEKTILKNISFKVASGQQVALVGSSGGGKSTLTSLLLRLYDPISGGIFVDCHDLREYKLQSYRRQISVVLQDSILFAASIRDNIAYGNLAATNKQIERAARLANAHDFIMDLPQGYDTIVGERGSTLSGGQRQRISIARAAVRNAPIVILDEPTTGLDQQSEYLVNQALNRLTRGKTTFTVSHNLKAIQNADLILYMENGQILEKGTHEELMLKKGRYSQMYILQASLGKENKFLGLGVRS
>NC_019678.1|WP_015118552.1|3049663_3050818_+|histidine-phosphatase-family-protein
MMNQEFDQTRVILVRHGQSTYNEQKRYQGCCDESLLTQKGKQQAFQTGIALSKIKFDAIYTSPLKRTRQTAWEIFKVNNFSENLNSKLSINSNLKEVYLPGWQGLQYKYVREEFAEEYRIWEEQPHEFTTENTESNGHTLIKTRTKPVLQLYKKAEEFWQEILPLHRGKTILVVSHGGTIRALIGTATGIHPQKYHSIQQSNSGINILNFGNSLPGQFVKIEAINQTQHLGEVLPKLKNGKYGLRLLLLPVFGKPVKGNFEKISRFLRSTELDFCISNNNLDAQLISESIIEKQPSPPVNLQVSQDNFLDIWHQTISKRSQNHHSLNTGLVVADKNTISSTLAQVIGVKSPECLQLNQGEISILFYPISQNKPVLQAMNITGIS
>NC_019678.1|WP_015118553.1|3051122_3052139_+|NAD-dependent-epimerase
MSVLITGVAGFIGYHLAQRLLADGEQVYGIDNLNDYYDVNLKKARLAQLIPHTNFHFQQLDLNNREEILKLFKEQNFDYVINLAAQAGVRYSLENPFAYVDTNLVGFANILEACRHSQPKHLVFASSSSVYGTNTKIPFSVTDNVDNPVSLYAATKKANELMAHSYSHLYSLPITGLRFFTVYGPWGRPDMAYFKFVRAIEANEPINIFNYGKMQRDFTYIDDVIEGVVRVMHKPQKAQVDKAHKNARYKIYNIGNNKPVELLEFIQVIEKALGKEAQKNFLPMQPGDVPRTYADVDELIQDVGFKPTTTIEQGIEKFVQWYKDFYPCSNQEFSQIML
>NC_019678.1|WP_015118554.1|3052253_3052622_-|response-regulator-transcription-factor
MNQILIVEDEIRLAAFLQKGLRKKGYITTVVEDGQQAVEMASSKQFNLMLLDLGLPVKDGLTVLQELRNQGKKLPIIIMTARSDEREKTEAIAYGADDYLTKPFPFQDLLSRIEEYLCLVTG
>NC_019678.1|WP_015118555.1|3053386_3054271_-|polysaccharide-deacetylase-family-protein
MENSKSFILPYKIFIALLIITSTLCLSLILPVNLKLAQLVGLDKPEEKIINAATNNQQLVAQFQNAMEATLNEQFKRQSLLSAAPSSFNSKVIYEIKPIKNKKVIALTFDDGPWEKTTQQTLDILKKNNVKATFFVVGKALQNNPRLGKQIVADGHAIANHTWNHWYHFMNPQVAAFEIDKTTELIYKVTGVKTNLFRPPGGHLSNGLVAHAKNKKYATLMWSADSRDFQKPAPATMVNTVLKNARPGGIVLLHDGGGDRTNTVKALPQIINKLRQQGYSFVTIPELLEMQEKK
>NC_019678.1|WP_015118557.1|3055362_3056031_-|response-regulator-transcription-factor
MSQILIAEDESRIASFIAKGLRANGFVPTIASDAQETLNLAIGNNFDLLILDLGLPGKDGLEVLEEIRGQGEDLAIIILTARDDINDKVAGLEGGADDYMTKPFRFEELLARIRLRLRNSQVSQGTEEMLLKAGSVVLDLRTRKAQVNGDNIDLPAREFTLAETLFRHPGQVMSREQLLDRVWGYDYDPGSNIVDVYVGYLRKKLGHELIETVRGMGYRLRR
>NC_019678.1|WP_015118558.1|3056137_3057694_-|HAMP-domain-containing-histidine-kinase
MSVNSVKNHSQPSDTPAKTAQTALHKWRGLFWATRTRILAWYVLIITFIFLVSIPAFRELLYARVDTRVRRELMEKIQTFNRLIQNEADSKEFSLTESETIQDSDWVNELDNRFVRPSSKKELKDFFNGFLTKQLPEDDTFLITFVDGKFFKSSPRARPKVFDEDSQIMRRWSKLVKPEKGEKDFDSDTGGIIYLSQPVKIKGETLGVLVVAHTIKGERDEVIEAVGVVIQVSSIVICIALLLSWIASGKILAPLRSFSVTARSISESDLSQRIPVRGKDELAEVANTFNEMMDRLEATFTTQRNFINDAGHELRTPITIIRGHLELMDRDDSEEVEETANLVIDELDRMSRFVEDLILLTKAERPDFLQLATVDVENFTQELFVKAQALAERNWCLDNSAKGMVIFDRQRLTQAVMNLAQNAAQHTTNTDTITIGSSIDRGKMKFWVRDMGEGIKDTDKSRIFERFARAANSRRRSEGAGLGLSIVKAIAEAHQGEVTLESRFGKGANFCIILPINS
>NC_019678.1|WP_015118559.1|3057936_3058761_+|tetratricopeptide-repeat-protein
MNLSSARHFFHQEIQQSDEYIDLGKAGLYIAQEEYSELDIEEYLNALDAMAMELEERLPSEKYPLKIIQCINQYLYDDLKFTGNIQNYYDPRNSFLNDVIERRVGIPITLALLYIEIARRIDFPMIGIGMPGHFLIRPDISEIGIFVDAFNHGEIMFPQDCQERLSQIYQQNLTLQPEFLAPVTKKQFLARMLTNLKYIYLNQQELEKALLCVERILLLFPSAALELRDRGLLSYQIGRFNQAAEDLQAYLLQVPDAQDASTIVRLLEKLGKNQ
>NC_019678.1|WP_015118560.1|3058910_3059357_-|SRPBCC-family-protein
MPTLEVFEQSIEINATSAVVEQCITERVLMHRWLNPALCCEPVGDWSTDIGSKSKFIIQIPVIKPTLISTVVEREPGLIVWGFDGYFKGSDRWECQPTNNGTRLVNRFEFRIPNPIVSMGFKIFAEKFTKQDMEAQLRRLKHVAETLG

Crispr_ID: NC_019678_13

• CRISPR_ID: NC_019678_13
• CRISPR_location: 3357048-3357164
• CRISPR_type: TypeV
• Repeat_type: A:N
• Spacer_info: 1 spacers
• Cas_protein_info: cas14k

Consensus repeat of NC_019678_13

Consensus_repeat	Method
TGGGAATGCTTTCTAAGAGGCTCTGCCTCGTTTAT	CRISPRCasFinder

spacers of NC_019678_13

>13.1|3357083|47|NC_019678|CRISPRCasFinder
TTTCTCGCTCCCCGTCTTTGCCTTTTTCTCGTTCCCTAGCTTCTCTG

CRISPR arrays and Neighbor proteins around NC_019678_13

CRISPR arrays

The CRISPR arrays of NC_019678_13

>merge|NC_019678|13|3357048-3357164|CRISPRCasFinder
TGGGAATGCTTTCTAAGAGGCTCTGCCTCGTTTATTTTCTCGCTCCCCGTCTTTGCCTTTTTCTCGTTCCCTAGCTTCTCTGTGGGAATGCTTTTTAAGAGGCTCTGCCTCGTTTAT

>NC_019678|13|12|3357048-3357164|CRISPRCasFinder
TGGGAATGCTTTCTAAGAGGCTCTGCCTCGTTTAT	TTTCTCGCTCCCCGTCTTTGCCTTTTTCTCGTTCCCTAGCTTCTCTG
TGGGAATGCTTTTTAAGAGGCTCTGCCTCGTTTAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015118794.1|3350986_3352405_+|response-regulator	unknown	unknown	gnl|CDD|223715
NC_019678.1|WP_015118801.1|3360586_3363277_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|226702
NC_019678.1|WP_015118795.1|3352938_3354336_-|amidohydrolase	unknown	unknown	gnl|CDD|238623
NC_019678.1|WP_015118798.1|3356389_3356923_-|transposase	unknown	unknown	gnl|CDD|224854
NC_019678.1|WP_015118789.1|3339316_3340315_-|septal-ring-lytic-transglycosylase-RlpA-family-protein	unknown	unknown	gnl|CDD|223868
NC_019678.1|WP_085977696.1|3354475_3355252_+|cysteine-hydrolase-family-protein	unknown	unknown	gnl|CDD|238245
NC_019678.1|WP_015118804.1|3365964_3367176_+|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl|CDD|236848
NC_019678.1|WP_015118799.1|3357286_3359104_-|aspartate-kinase	unknown	unknown	gnl|CDD|236018
NC_019678.1|WP_015118806.1|3370690_3372025_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015118790.1|3341235_3343254_-|family-10-glycosylhydrolase	unknown	unknown	gnl|CDD|224563
NC_019678.1|WP_015117596.1|3370057_3370471_+|IS200/IS605-family-transposase	unknown	unknown	gnl|CDD|376616
NC_019678.1|WP_015118805.1|3367347_3368478_+|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl|CDD|223715
NC_019678.1|WP_044291794.1|3365256_3365700_+|response-regulator	unknown	unknown	gnl|CDD|381108
NC_019678.1|WP_015118793.1|3345486_3350820_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NC_019678.1|WP_015118800.1|3359414_3360134_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_019678.1|WP_015118802.1|3363286_3365101_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|226702
NC_019678.1|WP_157229412.1|3343585_3344044_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015118797.1|3355378_3355819_+|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380392
NC_019678.1|WP_015117597.1|3368575_3369988_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14k	-	gnl|CDD|366606
NC_019678.1|WP_044290924.1|3344093_3345302_-|NupC/NupG-family-nucleoside-CNT-transporter	unknown	unknown	gnl|CDD|224883

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019678.1|WP_015117597.1|3368575_3369988_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14k	-	3.1e-17	56.9	2.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015118794.1|3350986_3352405_+|response-regulator	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.98706e-39
NC_019678.1|WP_015118801.1|3360586_3363277_+|PAS-domain-S-box-protein	gnl|CDD|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	7.52021e-50
NC_019678.1|WP_015118795.1|3352938_3354336_-|amidohydrolase	gnl|CDD|238623	cd01298, ATZ_TRZ_like, TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are catalyzed by atrazine chlorohydrolase (AtzA), hydroxyatrazine ethylaminohydrolase (AtzB), and N-isopropylammelide N-isopropylaminohydrolase (AtzC). All three enzymes belong to the superfamily of metal dependent hydrolases. AtzA and AtzB, beside other related enzymes are represented in this CD.	7.7562e-140
NC_019678.1|WP_015118798.1|3356389_3356923_-|transposase	gnl|CDD|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.00159308
NC_019678.1|WP_015118789.1|3339316_3340315_-|septal-ring-lytic-transglycosylase-RlpA-family-protein	gnl|CDD|223868	COG0797, RlpA, Lipoproteins [Cell envelope biogenesis, outer membrane].	1.77038e-52
NC_019678.1|WP_085977696.1|3354475_3355252_+|cysteine-hydrolase-family-protein	gnl|CDD|238245	cd00431, cysteine_hydrolases, Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It also contains isochorismatase, an enzyme that catalyzes the conversion of isochorismate to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of the vinyl ether bond, and other related enzymes with unknown function.	1.25124e-38
NC_019678.1|WP_015118804.1|3365964_3367176_+|hybrid-sensor-histidine-kinase/response-regulator	gnl|CDD|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	3.25906e-64
NC_019678.1|WP_015118799.1|3357286_3359104_-|aspartate-kinase	gnl|CDD|236018	PRK07431, PRK07431, aspartate kinase; Provisional.	0
NC_019678.1|WP_015118790.1|3341235_3343254_-|family-10-glycosylhydrolase	gnl|CDD|224563	COG1649, COG1649, Uncharacterized protein conserved in bacteria [Function unknown].	5.70233e-99
NC_019678.1|WP_015117596.1|3370057_3370471_+|IS200/IS605-family-transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	9.10616e-47
NC_019678.1|WP_015118805.1|3367347_3368478_+|hybrid-sensor-histidine-kinase/response-regulator	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	4.55847e-48
NC_019678.1|WP_044291794.1|3365256_3365700_+|response-regulator	gnl|CDD|381108	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains. This family is composed of response regulators (RRs) that are members of phytochrome-associated, light-sensing two-component signal transduction pathways such as Synechocystis sp. Rcp1, Tolypothrix sp. RcpA, and Agrobacterium tumefaciens bacteriophytochrome response regulator AtBRR. They are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. Also included in this family us Methanosaeta harundinacea methanogenesis regulatory protein FilR2, also a stand-alone RR. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	9.57175e-60
NC_019678.1|WP_015118802.1|3363286_3365101_+|PAS-domain-S-box-protein	gnl|CDD|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	8.07146e-49
NC_019678.1|WP_015118800.1|3359414_3360134_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.8895e-65
NC_019678.1|WP_015118793.1|3345486_3350820_+|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	0
NC_019678.1|WP_015118797.1|3355378_3355819_+|cupin-domain-containing-protein	gnl|CDD|380392	cd06987, cupin_MAE_RS03005, Microcystis aeruginosa MAE_RS03005 and related proteins, cupin domain. This family includes bacterial and some eukaryotic proteins homologous to MAE_RS03005, a Microcystis aeruginosa protein of unknown function. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	6.01079e-76
NC_019678.1|WP_015117597.1|3368575_3369988_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl|CDD|366606	pfam01385, OrfB_IS605, Probable transposase. This family includes IS891, IS1136 and IS1341. DUF1225, pfam06774, has now been merged into this family.	2.1403e-08
NC_019678.1|WP_044290924.1|3344093_3345302_-|NupC/NupG-family-nucleoside-CNT-transporter	gnl|CDD|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	2.27179e-151

Protein sequences

>NC_019678.1|WP_015118798.1|3356389_3356923_-|transposase
MGRSRYKFIENNPHFLTCTIVNWLPIFSQPEFAQIIIKSLDFLSGSQRLTLHAYVMMENHLHLIASSKNISKEIAAFKSFTARSIIDKLKQNQAEYLLKQLRFHKKLHKTSQEHQLWQEGSHPQTISTQEMLIQKLEYIHNNPIRRGYVDEPAHWRYSSYRNYMDMKGILNIDVLEI
>NC_019678.1|WP_015118797.1|3355378_3355819_+|cupin-domain-containing-protein
MINSCVIPVIKSPSDYQAYRISPDDSNRLAIVFDPAIANSSLTCCVEIFDVGGKTPPNRHLFALEMFFVLKGEGKATCDGKTINIKAGDSLLVPATGTHLIENTGSGRLYTLTIMVPNEDFAELIRSGTPVELDEEDMAVLGRQYQ
>NC_019678.1|WP_085977696.1|3354475_3355252_+|cysteine-hydrolase-family-protein
MMKPLKPLGVAPNAWMVNDTIADITRSQLDPQPVIVATETKNVCFDLAKIAIIVIDMQNDFCHPDGWLAHIGVDVNAARQPIQPLQNLLPVLRSQNVPVIWLNWGNRPDLLNISAGLRHVYNPTGEGVGLGDALPNNGAKVLTKDSWAAAVVDELEQLPEDIYIDKFRMSGFWDTPLDSILKNLGKTTLLFAGVNADQCVLCTLQDANFLGYDCIFIKDCSATTSPEYCWLATLYNVKQLFGFVTDSVRIVEGIESGG
>NC_019678.1|WP_015118795.1|3352938_3354336_-|amidohydrolase
MNFTIQNVLIPTEDDYATVDVQIQDGKIAEVSSGLDVIGEAIDGTNKLLLPGFVNAHTHSSEMWQRGIMSIYPLELWLAELYDFAPLDTEQVYLTALGTAVETLLSGGTTVVDHLVLIPGKELETITVAVEAYRKIGIRAVVAPLIQDESLTAGMPSGESEVSHEDYFRSTQATLEIMESAIKQFHKPEDGIYIALAPTGIQLCSDALFKGCIELSDKYNLCRHSHLLETKAQEKLAQEKYGCTAVEHLQTINYLNHRTSLAHCVHLTDKDISILAETKSTVVHNPLSNLRLGSGIAPILKYRQAGVNISFGCDGASSNDSQDLLEAIKIGSILHNVTDLDYQHWITPRQSIEMASLGGAKGLNLGEEVGSLTLGKKADLVMYDLTSLSLLPRTDPVGLLVLGRPTNVVDSVWVNGNLIVADGTVKNINLDNLKQELFKHSQWQTKRKSKTVKEIEAHYRKVMGL
>NC_019678.1|WP_015118794.1|3350986_3352405_+|response-regulator
MTLDNNLKLSETDDDILFFEEEATDNITVNTSSEAVWKVLIVDDEPTVHQVTKLALKNLTFEGKPIIFYSGYSSQEGKKLIAENPDTALILLDVVMDSNDAGLQVVEYIRKELENKRVRIILRTGQPGDAPEESVITNYDINDYKLKVELTRQKLITSTIAALRSYRDILTIEEQAVQLSETLKTLQNTQLQLVQSEKMSALGNLVAGIAHEINNPIGFVAGNLKMAKEYVGDLFSLIDLYQQHYPNPQPEIESEIEAIDLEYLRDDLPKLFNSLKIGSERIRNISTSLRTFSRADTEHKIPFNIHEGIDSTILILQHRLKADESHPVIKVIKNYGDLPLIECYSGQLNQVFMNLLANAIDALEEYNVGKSFEEIEAHSNQIIITTTLTPDKTTAIIKIADNGLGIPEAVQQRIFENLFTTKAVGKGTGLGLSIAREIIVDKHKGNLTFNSEIGKGTEFVIQIPVKSVSSEQ
>NC_019678.1|WP_015118793.1|3345486_3350820_+|AAA-family-ATPase
MVIITGYEILEQIYESHNSAVYRGKREEDNQPIILKILKQECLTPLQLTRYKQEYEITCNLEHPGIIKAYDLQQDHFLVMILEDFGGESLRNLLYKRKFNLFESLEIACQITDSLAQIHAAQVIHKDINPSNIVFNPVSKQLKIIDFGISTKLGSEHTVLSSPNALEGTLAYISPEQTGRMNRSLDYRTDFYSLGVTLYELFTSQLPFTGDDAMELIHCHLAKQPVSPHEISYKVPRMVSQIVMKLMAKTAEERYQSVWGIKADLETCLEQLKNYNCIIDFDLAKEDISSQFHIPQKLYGREQETSILLSAFERVINVVSKTEMVAVTGYSGIGKSALVKEIYRPITRQKGYFISGKFDQFQRNIPYSAVVKAFRGLVKQLLSEPLLQLQEWKQKLLSAIQPNAQIIIDVIPEIELIIGRQPAVEDLKGSEAQNRFNSVFKSFIRVFCQAEHPLVLFLDDLQWADSASLQFIELMMTDDKMHHLLFIGAYRDNEVDANHPLIILLEKLNISIPTHQIKLTPLNQKNITSLIADTLHRDIKDVASLAKLVASKTDGNPFFVNQFIYNLHSEKLIYFHVSQGIQKPRWEWDISQIEEMDITDNVVELMISKLIRLPKPTQQVLRLAACIGNRFTLNTLAIVSELTPIAAFQNLAIAIQQGFILPTSGLEFLSGEMLSSQLVINNFKFLHDRVQQAAYSLIAEYEKQAVHLQIGWLLYSNFSSQEQLDHIFELVDHLNSGRELIINDGEKIELVKLNLSAAKKAKDAIAYDAARSYLYICKEELPLDSWFRFYELTLDIYKQLAEVEYLNGDFASSEYLINRIIEKANNPVEKADIHNLLVLQFTLQGKLNEAIEAGKNGLQYLGFDLPKTNLDEALEIATTKANKLLQGKEVASLINLPDMTQPDKIIALRLLNNIDVPCYLTNQKLYSIAIIKMLNLSLEYGNLAESTKGYVLFGLLLGAVWGEYQRGYEFGKLAINVSQKYRNLNQECKTCMILATSIVFWVKHIRHTHEISHTGYQASIESGDLQYSGYILSSQLINNLYADVSIEKSIDEANNCLQFVNKNTNIFARDTILAAKLCLCNLNGETKELSEFDSPELSESEYLQSCWQRQSYMPLFNYYTFKSFVLYLYNKPVEALEVVIEAEKLKEFGISTITVAEQNFHQSLILTALYSSATFAEQKQYWHQLERNQKQMKIWADNCEANFLHKYLIIEAEIARISGNKLEAMELYDLAIASAKTHDFIQNEALANELAAKFWLGMNKEDFAQIYIRKAYNAYQAWGAKHKVADLESQYSFWLNPRLIKITDNLNPKNNNYQTTINQNSTTTNFGESLDMETVFKVSQTISNEIMLAKLIEKLMKTVIENAGAQTGCLIFINNGELVIESVINADGEVEIQHSIPITAFKNLPISVINYVARTQKNVLLDEVNQREEFANDFYFINEQPKSLLCIPILHQGKLIAILYLENNLTTAAFPPQRLQLLKLICSQAAISIKNATLYSTLEQKVTERTKQLSQAIENLQEAQKQLVESEKMAALGSLVAGVAHEINTPVGTSITAASTLKDETTIFNDAVAGGALKRSSLNNYLEIASESTDLILNNLNRASDLIQSFKQVAVDSSNLEKRKFAIKPYIQEILNSLAPKFKHTALTCKVEGENHVEIDTYPGAVAQIVTNLVMNSLKHAYQSGEKGQLHFQIKQQQDVVLIEYSDDGCGIPSENLTKIFEPFFTTARNEGGTGLGLHIVYNLVTQKLQGKIDVKSEVDLGTIFIIALPLVCLVKRTEKQ
>NC_019678.1|WP_044290924.1|3344093_3345302_-|NupC/NupG-family-nucleoside-CNT-transporter
MMRLISLLGIFAFVGISYSLSVNRRAIRWVPVLWGIALQLVFGILILRTKPGFVVFKFLGDVVSQFLNYSDAGAKFVFGDNFEEHYIAFKVLPTIIFFSSFITILYHYGILQRIVQVVANVMMKTMKTSGSESLSAAANIFVGQSEAPLLIKPYVATMTRSELHAVMTGGFATIAGGVMAAYISFGVSAEHLIAASVMSAPAALAVSKILYPETESSPTAGEVKIEVKSDYSNAIDAAATGASEGMKLALNVAAMLIAFLGLLALANGILGYIGSRTGLPQLSLEWIFSYLLAPVAWLMGVPWADCGQVGILLGKKTILNEFIAYQDLQKMVAESAISERARIIATYALCGFSNIGSIGIQIGGIGAIAPNRQADLAQMGIRAMIGGAIACFMTSCIAGMLL
>NC_019678.1|WP_157229412.1|3343585_3344044_+|hypothetical-protein
MLRKLTYILFLSSLICVLGFSSVRNYVSKKSPTVSCHEWGFSSKAEKYYTHPEKIVLEPWRGQHHVYGIFQIPGGYLNDKLLEVKVPGSKTYCGVLNYGGTVAIDGVKAKPGHYLMKGMLNTRFAIKLILQGKQEELKKPDNWNLGYTKIDS
>NC_019678.1|WP_015118790.1|3341235_3343254_-|family-10-glycosylhydrolase
MASSSARFPDITNHWARPFIEALARRGILNGYPDGKFRPDNSVTRAEFAAIITTTFSRIPKKREYVSFVDVPENYWAASAIQKAYETVFITGFPNNYFRPGNRIQRINALLSIISGLGMTSKVSNDLLPVLGQIYRDAYKIPDYAKPTAAITTRAGMVASHPNPNLLNPTLAATRADISVFVYQALVWLGEEQPISSQYIVNPPANTNIPAPPPGSVQIEPQREFRGAWVASVWNSDWPSRAGLSADRQKAELIQLLDKLQELNFNALILQVRPEGDALYDSKYEPWSAWLTGIQGKSPGYDPLEFAIAQCHKRNIEFHAWFNPYRASTSYRRVKNVSPHIAETNPEVVYRWGTQLWMDPGAKVVQDRIYNVIMDVVRRYDVDGIHLDDYFYPYPIRNLSFPDSKTYAAYRNTGGRLSLNDWRRNNVNIMMRRLWQGINSAKSHVKFGISPFGIYRPGQPAGIKGLDAYGTLYADAKKWLQQGWLDYIAPQLYWRIDQTSQSYPVLLRWWTSINSQQRHVYAGNTVARLDGKAWKQREIIKQVTISRSLREQLSLGNIFFSASAIEENRQGIAEKFKSLLYKEPALVPTMPWKDVIPPTSPVAVQTDNLKITWRSTSGEIRSWTLYQKIGNNWKLQKVLPEQTTETTVEPGTYALCAVDRMSNQSAGIVVNI
>NC_019678.1|WP_015118789.1|3339316_3340315_-|septal-ring-lytic-transglycosylase-RlpA-family-protein
MNQRLLWTVVAVISTVAGTPSISRAQAINEASITSQKTSEKNIVDAAVNESNYVITKIHAHKLGDREAATLYIRNIPAFTFLNSVSENSQNKANLAVESDYSNPVEKANAVAAKINDLVNNKVDANKITVSWNGTTGSKSESKTLIERYIIKVDDSELVEINSDTILPDATKNLRQDALQATNRLRRLVGKASPLKTIAGLPPELTKPEKQAVKIKKTSSNKHHTKKWRKAARGGRRFRGIASFYGAYFAGRKTASGERFNPSRMTAAHKTLPFGTRVRVTNMRNGRSVVVRINDRGPFIRGRVIDLSRGAAGVIGMIGRGIAPVRVEVLGR
>NC_019678.1|WP_015118799.1|3357286_3359104_-|aspartate-kinase
MALIVQKYGGSSVGSVERIQAVAKRVWLTAKAGNSVVVVVSAMGKTTDGLVKLASDISPVPSRREMDMLLSTGEQVSIALVSMALQEIGQPAISLTGAQVGIVTEAEHTRARILHIATQRIEKCLEQGRVVVIAGFQGISSTEELEITTLGRGGSDTSAVAIAAALSAEKCEIYTDVPGILTTDPRLVPEAQLMAQVTSDEMLELASLGAKVLHPRAVEIARNYGVQLVVRSSWTDDPGTVVDSPEPKPRSLVNLEIARPVDDIEFDTNQAKVSLLRVPDKPGVAAQLFGEIARQKVDVDLIIQSIHDGNTNDIAFTVMSPILKKAEAVASAIAPALRSTDSETEEAEVMVQQNIAKVSIVGAGMIGRPGVAAEMFATLARKGVNIRMISTSEVKVSCVIDSVDCDKAVAALREAFEIESDSLSPSPSSSVPIRPSSPPVRGVALDMKQARLGIRRVPDVPGMAEKIFGTLAARNISVDMIIQSQRCHVIKNIPTRDIAFTVARVEARAAQELLQQATAECGWGEVVLDMEIAKVSVVGAGMVGQPGVAAKMFESLSEENINIQMITTSEIKISCVVAEEQGVKALKAIHTAFELGGTEEFVVPG
>NC_019678.1|WP_015118800.1|3359414_3360134_-|response-regulator-transcription-factor
MSEIKVVVIEDHNLTRIGLKAALETRQDIKIVGEASNGTDGLNLLKNLKPDVATIDLGLPDIDGIELTRRFRQYQAEIGNQDTKILVLTMQNSDEAVLAAFGAGADSYCMKDIESDKLVEAVEATASSGSWIDPAIADIVLRQVRQEVSEGKSAADAKTVAIQAVDPEVEKVIETYPLTKRELEVLELIVSGCDNAAIAKELYLTIGTVKTHVRGILSKLCVDDRTQAAVRALRSGIVQ
>NC_019678.1|WP_015118801.1|3360586_3363277_+|PAS-domain-S-box-protein
MNQSYYPAENNNITQTEARFRRIIQATTQLVFFADADGRIAHFNQQWYQVTGLSESQSLGLNFICAVHESERDEFYESWLSAVKACESWEYEFRIIHKDKKAYWYVASAQPCFDEKQQVIEWVIVCHNINNYKEKEIALERRNEFLEILFSQLSEGVVAWDKTANTIECNQTAAEFHGLPNKSLPIEEWQQYYDVSPIQGSEAIRTEEILQHQVKQGQVVENQKITIVPKQGKTRTLLLNGNPIFNASGENLGAVLKMQDINSLQHDSVQTEIQKYFERLTLSLDAAKMGSWYWDSFTNKNIWTPYHDVIFGYGSGNGEHTYEDWASRVHPDDLPLAQAAWKDALYKHTDYVCEYRIVLPDNTVRWIESYGRYYYDDSGNALRMAGTVTDITERKKSEQALRESQRRYSTLARISPVGIYRCDGSANLLYVNQRWCDITGYNFDQVINQGWREAVYSQDKARVEAQVKNCVEQKIPLECEFRFQRPDNSVVWVLAQSVPEFDIDGVLIGHVGTITDISNQKQSEKALRASEERFRSTFEQAAVGICHADANGKFVRVNQKLCDILGYSRSELLERSFEEITYADDLQSDLDRVRDLLAGKIQNFSMEKRYICKNGGVIWIEITVSLVSQANGEQDYFLGVIKDISQRKEAQTQLLLRAQEQEELNVLLTQTATELRKRNCELDQFAYVASHDLKAPLRAIANLSQWLEDDLSEALEPENQRHLELLRQRVYRMEALIDGLLQYSRIGRVKNAEEKVDVNQLLAQIIDELAPESFNIKVKDNMPTLTTKSMLLRRVFINLIENAITHHNSACGNIEISVKDKGNCYEFCVSDDGSGISPQYHDKIFVIFQTLQARDKKESTGVGLSIVKKILETEGAKITVDSDVDKGASFCFTWHK
>NC_019678.1|WP_015118802.1|3363286_3365101_+|PAS-domain-S-box-protein
MPKINLFAKIRTVWHSLPVRHRGAIIIALPFSCLIVTLYASVSLRQNAIATYQQIDHTKTILLDSNRLLKILLDAETGTRGYIISRNQTFLEPYNTARQELPKIINRLEEKLSDDAEVEKFKRIKTLARQNISILEQRIEQVNQRKRNNIDSPASDILLYQGKNVMDTIRDEIDALREAELNQLDIYRQNLNPIRNQNITVLWITLAISVSSYVGAIYLFSKLDWQIEGQELQLKQKKSLLEGIMGNVVDGIITLDKQDRIDSFNQAATEMFGYQSQDVMGKNIDFLISKTEKNIDTQLSQKISTSHQSLPVYALANRKVGSSFPVEISISDLQHDNGKMVIVRDITEQTQAREKLEANVQELSRLSVLLASTNQALTERNQELDDFAYIASHDLKAPLRGIANLSQWLEEDIQNDLSPENQNQFELLRKRVYRMEALINGLLEYSRVGRIQTSEEKVDVRELLAEIIDSLNPPAEFNIEISSELPTFTTKKLLLRQVFANLLSNAIKHHPRDDGNIKIFVEDKGNVYNFIVADDGKGIDPKHKDKIFTIFQTLQSRDKKENTGVGLSIVKKIVESEGGKIHLNSELGKGATFSFTWHKSTMGQ
>NC_019678.1|WP_044291794.1|3365256_3365700_+|response-regulator
MQENDRTVNILLVEDDEVDIMNVERAFKKANINNPLYVARNGIEALIMLRGGNEQLCQVPNERRLILLDINMPKMSGLEFLQTIRADKDLKLTPVVMLTTSNQDKDMIEAFDLNVAGYLLKPVTFSRFVELMQALNSYWSFSEMPNS
>NC_019678.1|WP_015118804.1|3365964_3367176_+|hybrid-sensor-histidine-kinase/response-regulator
MEEIYNILIIDDDEVDRMAISRALKAAGIKMKLLEASDYSEAVEILEKTDFDCIFVDYLLPGKDGLAVVQEIRASGSKVPLIVLTGQGDEQTAVELMKAGASDYITKSRITPDLLSATLRNVIRIYEAEVQIELFNKQLKQSNELLKKKNRELEEKREQIHIQNLKLLEASETKSKFLATMSHELRTPLNAIMAFSQMLQRKNKGNFSRQQVDMIERIHGNGKNLLALINDILDLSKIEAGGLKLYPEKFDLSQLITTTVEELLSLKSQTELDVKVELKLRDTKVFNDRNRLRQILVNLISNAIKFTEKGMVLIEAKEISDTHFTVSVEDTGIGISEDSIKHIFEPFRQINQTISRKYAGTGLGLAITQSLVKMMNGIVSVESQLEVGSTFKVNLPRYIKVEE
>NC_019678.1|WP_015118805.1|3367347_3368478_+|hybrid-sensor-histidine-kinase/response-regulator
MSNNKLARQDRILVVDDIYDNLLVIETILEDEGYEIEIQQDSKLGLEMVEESPPDLILLDVMMPEIDGYEFTRRVRQNKQLPFIPILLITAHDSISVVEGLDAGADDFIRKPVDADELQARVRSLLRLKHSIDERDHMASLRQDFVSRFTHDLRTPLAASNRILKLLREGRFFEISPEIEQIFTTMITSNDDLLHMVNSLLEVYRYEADCKQINFDKISIYDLVRDVIQELTPLAEEKELKLKSNLENIDLENSEIYTIFADRIEIKRVLTNIIGNAIKFTKTGFIEVNLKLYSQTAQISIKDTGPGMAPEEQAILFERFRPGKHKNSGSGLGLYLSRCIVEAHNGSINVESESGTGSTFTISLPVQSEQLTANAK
>NC_019678.1|WP_015117597.1|3368575_3369988_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MYKTVPIKAKFTDEEKAFWVDQCEHSNSLYNSAIYLARQNHYAMLLERKANTTYWCGDELRSGWKTYRLETNYYHLDKQLKTCIHYFSLAAQAAQQTLKLVGESITSYNKLVDKYYLGDGSRPSIPKYRKSGGLFAVTFPKQALACHNGYIYPSISKATKPELITSIKLILPEFISFDWIKEVIIRPSRGEFWVDWVIDDGKQPIINNKSLNYNHAISIDHGVKFWLSAVTTLGKSFIVESPQLKTALHKYRNQVQQHKKNKPSRYWDNYLDRITAKRNLQVRDAVNKAARFIINKCLKDGIGNLVIGWNEGNKTNINIGRNNNYEVVSMPTKRLIERLRQLCEEYGIRFHITTEEYTSKASFIDNDELHQYGAKPIEWKPSGKRISRDVYRTKDGLLIHADLNAASNILRKVADQIFINSGIAKLAFEIIKRGALTHPKRYDIFSNLKRSYRKQTMSRSMSLDYGVTTA
>NC_019678.1|WP_015117596.1|3370057_3370471_+|IS200/IS605-family-transposase
MAKLSASDYEYRRAEKSVSSINYHFVFVPKRRKAVLVNEIAMRLQEIIFELVKEHGWRLIALEVMPDHVHMFINSPPHESASQIAKWVKGRASNILRKEYPQLKKLPTLWSPSYFVATTGQVSTDVIRKYIENQTSK
>NC_019678.1|WP_015118806.1|3370690_3372025_+|hypothetical-protein
MDTNLKTAKELHSQLIDFVLDAEGDLAVSLEAFSAEQLANFSQSQSQAGVLQEMVLNMFLTEGMVGDKKLVDIFLESHPDLSPEQSDIVNGWERSFAGLFAANKISDDGCFLRNWLTDKQYLVKIDEKEQQQLKRAKEGEILLARIVPINDSSWMFSSPITLMGRLGKPKLAVAIGNFKNNYKNNLYGDAPELLEEAWLSVEKYHQNFVEFFDSDEVTLPGYQLEQKLSELQEQVQESRLAAAGIDSSKSLKEMAQDADVSDEEMTGVAEEMGVESKVLSQVLDSNKSVKMVTPKVELPTHLKKAEAVTVLSFPRWGQIFLTNYTQFKNLLADNNIEEQTNSAKLVQEYLESPEIKACIWQRLSEEYPQQLEKLLQQVLNRPDFNLETDYVDLLKEFNKNLNVELPEIASVPLHLHNLFQEALSEVKGKSSKKGKIKSKGGFGS

Crispr_ID: NC_019678_14

• CRISPR_ID: NC_019678_14
• CRISPR_location: 3401060-3401167
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 1 spacers

Consensus repeat of NC_019678_14

Consensus_repeat	Method
CTTCAACCTTACCTTTTCCCCTCTCCCTTTATAAGGA	CRISPRCasFinder

spacers of NC_019678_14

>14.1|3401097|34|NC_019678|CRISPRCasFinder
AGCTAGAGGTAGGAGTAGCTTAGAGTTTTCGCAA

CRISPR arrays and Neighbor proteins around NC_019678_14

CRISPR arrays

The CRISPR arrays of NC_019678_14

>merge|NC_019678|14|3401060-3401167|CRISPRCasFinder
CTTCAACCTTACCTTTTCCCCTCTCCCTTTATAAGGAAGCTAGAGGTAGGAGTAGCTTAGAGTTTTCGCAACTTCAACCTTACCTTTTCCCCTCTGCCTTTATAAGGA

>NC_019678|14|13|3401060-3401167|CRISPRCasFinder
CTTCAACCTTACCTTTTCCCCTCTCCCTTTATAAGGA	AGCTAGAGGTAGGAGTAGCTTAGAGTTTTCGCAA
CTTCAACCTTACCTTTTCCCCTCTGCCTTTATAAGGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015118828.1|3396768_3398988_-|amino-acid-permease	unknown	unknown	gnl|CDD|273347
NC_019678.1|WP_015118831.1|3401766_3402147_+|DUF4359-domain-containing-protein	unknown	unknown	gnl|CDD|372990
NC_019678.1|WP_015118832.1|3402258_3403689_+|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_019678.1|WP_015118835.1|3411640_3414175_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|273865
NC_019678.1|WP_015118823.1|3389454_3390144_-|manganese-catalase-family-protein	unknown	unknown	gnl|CDD|226076
NC_019678.1|WP_015118826.1|3394416_3395385_+|S-layer-protein	unknown	unknown	gnl|CDD|306825
NC_019678.1|WP_015118833.1|3403718_3408755_-|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|273865
NC_019678.1|WP_015118827.1|3395511_3396159_-|peptidoglycan-binding-protein	unknown	unknown	gnl|CDD|225943
NC_019678.1|WP_015118824.1|3390520_3391501_+|YegS/Rv2252/BmrU-family-lipid-kinase	unknown	unknown	gnl|CDD|234850
NC_019678.1|WP_015118837.1|3415282_3416842_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_019678.1|WP_015118834.1|3408999_3411537_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|368641
NC_019678.1|WP_015118825.1|3392202_3393807_+|Rieske-2Fe-2S-domain-containing-protein	unknown	unknown	gnl|CDD|223523
NC_019678.1|WP_157229413.1|3387509_3388943_-|TrkH-family-potassium-uptake-protein	unknown	unknown	gnl|CDD|223246
NC_019678.1|WP_015118829.1|3399343_3400114_-|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl|CDD|235711
NC_019678.1|WP_015118840.1|3418974_3420036_-|3-deoxy-7-phosphoheptulonate-synthase	unknown	unknown	gnl|CDD|237376
NC_019678.1|WP_015118821.1|3386418_3387357_+|hypothetical-protein	unknown	unknown	gnl|CDD|377730
NC_019678.1|WP_015118839.1|3417899_3418805_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015118836.1|3414246_3415089_-|prephenate/arogenate-dehydrogenase	unknown	unknown	gnl|CDD|180970
NC_019678.1|WP_015118830.1|3400113_3400869_-|sirohydrochlorin-chelatase	unknown	unknown	gnl|CDD|225049
NC_019678.1|WP_157229414.1|3417181_3417751_+|DUF1517-domain-containing-protein	unknown	unknown	gnl|CDD|369378

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015118828.1|3396768_3398988_-|amino-acid-permease	gnl|CDD|273347	TIGR00930, Solute_carrier_family_12_member_1, K-Cl cotransporter. [Transport and binding proteins, Other].	5.28073e-142
NC_019678.1|WP_015118831.1|3401766_3402147_+|DUF4359-domain-containing-protein	gnl|CDD|372990	pfam14271, DUF4359, Domain of unknown function (DUF4359). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 130 amino acids in length. There are two completely conserved residues (P and S) that may be functionally important.	6.34858e-47
NC_019678.1|WP_015118832.1|3402258_3403689_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.19882e-73
NC_019678.1|WP_015118835.1|3411640_3414175_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl|CDD|273865	TIGR01901, Heme/hemopexin-binding_protein, filamentous hemagglutinin family N-terminal domain. This model represents a conserved domain found near the N-terminus of a number of large, repetitive bacterial proteins, including many proteins of over 2500 amino acids. Members generally have a signal sequence, then an intervening region, then the region described by this model. Following this region, proteins typically have regions rich in repeats but may show no homology between the repeats of one member and the repeats of another. A number of the members of this family have been designated adhesins, filamentous haemagglutinins, heme/hemopexin-binding protein, etc.	1.56327e-24
NC_019678.1|WP_015118823.1|3389454_3390144_-|manganese-catalase-family-protein	gnl|CDD|226076	COG3546, COG3546, Mn-containing catalase [Inorganic ion transport and metabolism].	7.80623e-90
NC_019678.1|WP_015118826.1|3394416_3395385_+|S-layer-protein	gnl|CDD|306825	pfam00395, SLH, S-layer homology domain.	3.40414e-08
NC_019678.1|WP_015118833.1|3403718_3408755_-|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl|CDD|273865	TIGR01901, Heme/hemopexin-binding_protein, filamentous hemagglutinin family N-terminal domain. This model represents a conserved domain found near the N-terminus of a number of large, repetitive bacterial proteins, including many proteins of over 2500 amino acids. Members generally have a signal sequence, then an intervening region, then the region described by this model. Following this region, proteins typically have regions rich in repeats but may show no homology between the repeats of one member and the repeats of another. A number of the members of this family have been designated adhesins, filamentous haemagglutinins, heme/hemopexin-binding protein, etc.	3.82395e-22
NC_019678.1|WP_015118827.1|3395511_3396159_-|peptidoglycan-binding-protein	gnl|CDD|225943	COG3409, COG3409, Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane].	5.7069e-21
NC_019678.1|WP_015118824.1|3390520_3391501_+|YegS/Rv2252/BmrU-family-lipid-kinase	gnl|CDD|234850	PRK00861, PRK00861, putative lipid kinase; Reviewed.	5.3144e-165
NC_019678.1|WP_015118837.1|3415282_3416842_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.1686e-39
NC_019678.1|WP_015118834.1|3408999_3411537_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl|CDD|368641	pfam05860, Haemagg_act, haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins.	5.43454e-21
NC_019678.1|WP_015118825.1|3392202_3393807_+|Rieske-2Fe-2S-domain-containing-protein	gnl|CDD|223523	COG0446, HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only].	2.79517e-58
NC_019678.1|WP_157229413.1|3387509_3388943_-|TrkH-family-potassium-uptake-protein	gnl|CDD|223246	COG0168, TrkG, Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	1.47086e-91
NC_019678.1|WP_015118829.1|3399343_3400114_-|uroporphyrinogen-III-C-methyltransferase	gnl|CDD|235711	PRK06136, PRK06136, uroporphyrinogen-III C-methyltransferase.	5.9699e-142
NC_019678.1|WP_015118840.1|3418974_3420036_-|3-deoxy-7-phosphoheptulonate-synthase	gnl|CDD|237376	PRK13396, PRK13396, 3-deoxy-7-phosphoheptulonate synthase; Provisional.	0
NC_019678.1|WP_015118821.1|3386418_3387357_+|hypothetical-protein	gnl|CDD|377730	pfam06897, DUF1269, Protein of unknown function (DUF1269). This family consists of several bacterial and archaeal proteins of around 200 residues in length. The function of this family is unknown. The family carries a repeated glycine-zipper sequence- motif, GxxxGxxxG, where the x following the G is frequently found to be an alanine. As glycine-zippers occur in membrane proteins, this family is likely to be found spanning a membrane.	0.0002865
NC_019678.1|WP_015118836.1|3414246_3415089_-|prephenate/arogenate-dehydrogenase	gnl|CDD|180970	PRK07417, PRK07417, prephenate/arogenate dehydrogenase.	2.0016e-164
NC_019678.1|WP_015118830.1|3400113_3400869_-|sirohydrochlorin-chelatase	gnl|CDD|225049	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism].	1.48011e-34
NC_019678.1|WP_157229414.1|3417181_3417751_+|DUF1517-domain-containing-protein	gnl|CDD|369378	pfam07466, DUF1517, Protein of unknown function (DUF1517). This family consists of several hypothetical glycine rich plant and bacterial proteins of around 300 residues in length. The function of this family is unknown.	1.05352e-31

Protein sequences

>NC_019678.1|WP_015118830.1|3400113_3400869_-|sirohydrochlorin-chelatase
MSAAYLLVSHGSRDPRPQVAMEDLAKSLRNKLENYSNYDGSSSVLSPTKCDYLIGTAYLELHPQPLHEQIVDFSQKVIANGCRHLKILPLFLLQGIHVTEDIPEEVELAKKTLAEDISIELQPHLGSYFGLQRLMAKKISDISLDGKIIVAHGSRRVEANRNIETMAISLNAVAAYWAVSPSLKDIVTQLVADGKKKIGIVPYFLFAGGITDAIAQSIQDLKLQFPMVSFELYEPLGANGELIDLIWDLMQ
>NC_019678.1|WP_015118829.1|3399343_3400114_-|uroporphyrinogen-III-C-methyltransferase
MQKENTKNVVGKVYLLGAGPGDPGLMTIKGKALLEVADVVIYDALVSPGILAMVNPHAEKINAGKRRGRHSLPQHQTTELLIEKAQDNAIVVRLKGGDPFVFGRGGEEMQDILEAGVSVEVIPGITSGIAAAAYAGIPLTHRLYSSSVTFVTGHESVGKYRPAVNWLSIAKGSETIVIYMGVQNLPNIVEELLKAGLDKDTPIGLIRWGTRPEQEELIGELDTIVETVEKNNFEAPAIIVIGAVVKLHSVLGMGNG
>NC_019678.1|WP_015118828.1|3396768_3398988_-|amino-acid-permease
MKFLFKQDSPEVQADESNSVEAQSSGLGTFGGVYTPSILTILGVIMYLRFGWVVGNVGLVGSLIIVTLATSITLLTSLSVCAIATDKVVRVGGAYYMISRCLGIEVGGAVGISLYFAQALSIALYTIGFAESVVQTFGSLNQTYVALITTILVAILAVTSAQVAVKAQYVIMGAIVLSLVSLAFGGAIPNVTPQGWDIPSDGVPFWGVFAVFFPAVTGIMSGVSMSGDLSNPSRSIPRGTLAAVGTGYLVYMILPLIVSMRADSATLVSVPLAMKMMSFWGPAILLGVWGATLSSALGSILAAPRVLQALARDGILPRWLSFLGRGSGENDEPRIGTWVTLGVAIAAVCIGDLNLIAPVLTMFFLTTYLVLNVSASIEGLLQSPSFRPSFKVHWIWSLLGGIGCLAVMLLINAVATIVAAAIVLAIFFWLQQRELTTTWGDVRQGIWMALLRTGVFQINRVQDTKNWRPNILVFSGSPYKRWSLIQLAYALTHKRGFITVSSVVSSGTRDLARQIQLENTIREQLNKQHVQALVRVVTAPNPFEGMLQLVEAYGLGPLVPNIVLLGDSEQESRRDRYCNMLVQLHYAQRSIMVLRENAELGFGRFKRIDVWWGGMQDNGGLMLLLAHMLRSTIEWRDAKIHIKLMVSSESGTKDAETNLNAILKQFRIQATPEVIFAANRSFETVLHESSQDADIIFLGMATPTDRDFTEYYEKMHARTANLPTIIYVMAAPDFAFSEV
>NC_019678.1|WP_015118827.1|3395511_3396159_-|peptidoglycan-binding-protein
MSNQFAKIFLFPLSIVSAIAVATVPFTESATAQRRIGAIADGNMTEYSPSSAPLLRRGSRSQAVKDVQLLLNQNKFYYGRMDGIYGPRMYSSVVSFQRSRNLPATGVINSKTWEALIDLDKRNSPTRFAYLGKYSPSTAPMLRLGSRGRAVRDVQTFLKQQGFYVGQVDGIYGRATASAVKSFQQNRAKLRADGIVGSTTWQAMINDKKGPFAIR
>NC_019678.1|WP_015118826.1|3394416_3395385_+|S-layer-protein
MNNLRRLPIISASIVTIGLAIGAAIPLVTNAQSSPQSTFPDVKPDYWAQPFIKGLAERNVITGYPDGRYRPKQALDRDEFAAIIRKAFDQDKEKQIKSGSIYKDVPEGYWANKAIEEAVEAGFLSGNENLFRPRKEVTKLEAINALARGLDLSYKPATVTTTTPKIIPPYIRRRIARRKRKSRVMLPIAMTSLMQPLLIQKANAAKTPKISQNNSGNSSTAANNSKQNTTATAPLSAASIVQQAYKDANKIPENAVPRVAAATKQNIVVNYPNSNILNPNRAISRGETAALVYQTMAAQGKVPPIENNSLASKYIVKFKDVK
>NC_019678.1|WP_015118825.1|3392202_3393807_+|Rieske-2Fe-2S-domain-containing-protein
MNYKDIRVANAKDLKKGEMRQVSVEDNEILLARVEDGFFATVAHCTHYGAPLVKGILNGERVICPWHNACFGVKNGKLEEPPALDALPHFPVRVEGEDLVVKLPEKISSQRIPEMGRYNPQADNRTFVILGAGAAGSAAAETLRQAGFEGRVVMLTKEDILPYDRTALSKKYLQNDSVKDSLILRSLEFYNQWDIEVYSHKSVTKVEPVKKTITFEDDTIFEYDALLVATGGKPRNLKVPGADLDNIFTLRKPEDADKIVAVAENAKTAVVVGSSFIGMEAASSLAQRDIKVTVVAPGTVPFEKILGGDIGATFRKLHESNGVSFRMGTKVKQFEGKGKVETAVLENGESLNADLVIVGIGVEPVTDFLQEIELNEKDGSVIVDEYLQAADNLYVAGDIARFPYAATGELTRIEHWRLAQQHGRVAARNMIGEKIKFASVPFFWSGQFGVKLRYAGHAEEWDDIIIQGNLDEQEFLAFYVKDNQVLAVAGSQHDKDIAAITELMRLQQMPSEDEVRKSKINWVEKLTSEQLAIG
>NC_019678.1|WP_015118824.1|3390520_3391501_+|YegS/Rv2252/BmrU-family-lipid-kinase
MSRQKACLIFNPVSGNADSEQELERIKQLLSTQFDLDIKFTTKEVGADKLANVAVENNFDIIIAAGGDGTLSEAARALGETTIPLGVIPRGTANAFASALGIPDTLDEACETILSGKTRRIDIGRCNGKLMTLLAGIGFEAETVENASRDAKQRWGALAYLVSGIQQLREIELFDAEIETDDKIIRVSAGALTVANAAPPTSILAQGPAGILYDDGLLDITIISSNTWASAIAASYHLLQSGLRGDAAKRDDIGYIRTKRVKITTDPPQKIVLDGEMIGNTPLEVECVPGGLTVMVPMLPAEKVSEKLEGLPDLEIEEKSSAVTNE
>NC_019678.1|WP_015118823.1|3389454_3390144_-|manganese-catalase-family-protein
MFFHKKELIEKEVKIDEPNPRFAQLLLEQFGGATGELSAALQYWVQSFHTEDAGIRDMLQDIATEEFSHLEMIGKLIEVHTSNVDQTDAFKSTLFAVRGKGPHFLDSQGSAWTATYLNEGGSMVRDLRANIAAEAGARTTYESLIQLAPDSGTKETLVHLLTREISHTKMFMKALDSMGKLTDPFFGNIQPDSTVDIYYNLSTNGKDERGPWNSDENFRYIADPMKEKA
>NC_019678.1|WP_157229413.1|3387509_3388943_-|TrkH-family-potassium-uptake-protein
MAFFSIPVCLLWGEFYAILPFIICGIIPLIIGQLLYRLFSRGAEETKIRHAMITAALCWLIVPIIGAIPFLMVASNLAAASETSQTILNFQNPWNALFEAFSGFTSTGLSVALRASQLPRSLQWWRSFMEWIGGVGVIVLVISLLETTTDAYQLYSSEGREKRIASNVQATARRIWWIYLIYTIASIFIFRIAGMPWWDALNHGMAGMSTGGFSVRDDSIGSYSSIIQMAVIPTMIIGAVSFPVHYRLLTKGRFSALWSDNQHQALWLLLASGIAFLGLINYSFFGSPLWLHTVFQWASAFGTCGFNTIDLYDWSNSAKLLLTLAMIVGGTAGSTVGGFKLNRLVFLSKGAVWRLRRISLKSDESMSYRLDGEVLNETEATRKIEAAAVLGFLWIVILIIGVFILLQLALPDYSLSDVLFESASALGSVGLSVGITSPELPWLGKLTLIIFMWMGRLEIIPVLILFSEVGKKIRGKS
>NC_019678.1|WP_015118821.1|3386418_3387357_+|hypothetical-protein
MTSEYKRAVGVFTTRKDAESALQELKESNFPMDKVSVIARQPEESEDIAGIEVKENVGNKADEGAATGAFTGGALGGITGLLVGLGMLAIPGVGPIMLAGAEATAIATTVAGGAIGAASGGLVGALLGLGIPEERAKVYSELVSKGSYLVAVKGTEAQISQAQDILSRRGIKEWGVYDIPTSPADEMEGKVLGNYKYIVGVYRMRHNLKDAISAMRDTNFPMTQMYVVEKNPPPFASINSIDVKANLENYAGLGISAERKRHYDQLLERGNYLIVLSGNDDEIAEAESVLKQHSIEDLSIHDPAMISVSSEQ
>NC_019678.1|WP_015118831.1|3401766_3402147_+|DUF4359-domain-containing-protein
MKIVSIAAYAGAAALIALGVAMAGTNPSRAEYEEYATQRLSQYLKEQGCSKTPNLLDNLIKFNCGKLIDSASPQIKQIIKASTEKQDFLLFSVYRTNLQINTLIPSYKFETVGALDNFFTYKAQKE
>NC_019678.1|WP_015118832.1|3402258_3403689_+|protein-kinase
MSYCTNINCLSPQNPDTANFCMACGQKFLLKERYRPVKLIGHGGFGRTFLAIDEYLPSQSKCVIKQLYFAQSQANHFKQKAWELFRQEAIRLDDLGQHQQIPQLLAYFEQDEQLYLVQEWVAGNSLMQEIEQQGVFGESQIRQLLQKLLPVLQFIHSQNIIHRDIKPANIMRGCIAKDTNAKTSNSNLFLIDFGIAKHLHNTTLQQTGTKIGTPEYMAPEQLRGKVLPASDIYSLGVTCIYLLTGISPFDLFDVSEDRWVWRDYLLPQNKVSTRLGKILDKMLQNSLPNRYQKANDVLQALSRQAISSISHTQSFDLTATETEEIKIEIDYTQLQNLLKKGKWQEADKETWKIMCVSLSKPIGTYLFKSDIEKLSDDDLQKIDQLWMRYSKGHFGFSVQKEIYDSVDADYVQFCNMVGWATYNSYSSANSDYYYSLKAPIGHLPTRTWMGGSQWWRHADTFAAKLDRILWGVASSD
>NC_019678.1|WP_015118833.1|3403718_3408755_-|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MYSYSHCLLWGFSVALSLAPVIEAKAQLIPDNTLGKENSLVTPTKLLQRIDGGAIRGSNLFHSFKEFNIENGKSVYFSNPNAIQNILTRVTGKNASAIFGKLGVLGNANLFLINPNGIIFGENASLDISGSFSATTSSSILFDNGFEFSTTNLQAPPLLKVNITPGLQYPRSQQGDISSKANLTVGKDLNLIGKNLNLTGKLKAGRDLNLKAENNLQIRDSSEIPFVADASNNLLLQGAENVDIFALNHPDSGLFSGNDLILKSFNPVLGDARYFSGGNFRVEQLDGSLGNLQSPNDPIIRASGDVSFESYNGASLHILAGGSVNITGDVTIAGTDDENGLQEEVILSNGEELDIDGKNQATLDIRAGINVTDDVTEIISENGEFIPIIPNTERVKSSSDIVLEGNIKVDSPDGLVFLTNQYNENANLGDGNIQIQGNIETSSNSGNAGTIIVDASGNIEISSNIKADSLTAAGGNISLMSGATISMIGADIDSQSNIDDVSTNPIEGGDIKLIAPAIILEDASRVTVGITGLGTGGNLIVETDDIKIFDGSGLSSITNGIGDSGDINITTKRLIIDNSLPEINSISIDNINNYRTGISTFVSRLPKDNSFNSDFFNSGEGGNINVNASEFIKLTGNKSGTFSPTLRSESLASATLDTGIISGTNGSGAAGNTNINTGQLIITNGAGIATSSISPASLTTIYPDLLSSLIDETIPNPQADAIIQTISDKLSKIPDAGDSGELTVNANKIELIGSSGLTAATFSSGNAGNLIINNTDQFILKDGAIVSTSTFSSGNAGDLQVTTDKLNVSNGSFIGAGTLKEGEGGKVSITAFDSVQIIGTSNEDNENQVSSKITTTSETGATGNAGELIVDTKKLIIADGAEISASTESTLGGEIFLQGLESLVLSNGKISASSLDGEAGDIIINALDFVNILENSKIASEATGTGIAGFIEINTKNLNIADASVASVNSKQSAGYILVNADNVTINNLSRVTAETESGISGDIEFKNLQTLQLSGESLVSATTIDGEAGDITINATDEVKIAQSSKIASGAIGKGEAGFLEIVTNNLNISDNSDAVVSSAEEGDAGLISIKASNVNLTNKATISANTASGDGGDIELNNLKTLFLSQESFINATTQDGTAGNIKINATDLVTVENNSKLASEAVGDGIAGNIDIVTNQLNLTDNSQANVSSQGNGSAGSLLVKANNVFLRNTAEIAAKTNESGTDGHISLDILNNLELSNSLISASTINGEAGDIDINATNSVKLSDSSMIASEAKGTGVAGELRITTNQFTMTNSQANVSSRNNGVAGDILINANNLNLFQDAKISATTESGEGGNITLNMMNNLSVNSSQITASTIDGIGGDLIINATESINLTGKGGLLVQASNGGEAGFIEANTNQFDVLDNSEINVSSKLGQAGYLEIIANNLFLSEGKLTAETGVGEGLESGNITLNIQDLLWMQNDSLISAEAFDIANGGNITINNPQGFVIGLTFENSDIIANANQGNGGNIDITTQNIFGLGFRAQRTLKSDITASSKFGVNGEVTVNQLDENSAHQLINLPSTLVQNAKIKAGCAASAGNNFIIRGKGGLPQSPNDLFDGNTMLVELADLVVAAESASNISVENVNSTNIDNRENQIIEATGWVKDADGNLLFIAKGTSEDSAIYSASCQDFSATSK
>NC_019678.1|WP_015118834.1|3408999_3411537_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MFNIQAIFLGLSFAFAFIQVCQVNAQLIPDNTLGKENSLVNSINSLENRINGGAIRGSNLFHSFQEFNIENGKSVSFNHSASIENILTRVTGRNKSQILGKLGVIGNANLFLINPNGIVFGKDASLDIKGSFVGSTASFIDFEDGMQFSAVSPDKALLTISTPLGLGLDNPGEIRVQGDGHKLSASIFGLPFKDSGTEGLEVAPGKTIALIGGNIILEGGSLKTNSGRIELGSVASGKVDFTFTPQSMEFSYDKIETFKNIQLLKESSLQSNGFSAISNITNAGYIQLRGNTIYIKDGSMIFNSNQTNLTSKGIDINATESLEIIGSNIQESQFSSLRSQTLSDATGGDIKIDASKLVIKDGGAISGYNFGSKFGPNIKIKASDYVENIGSSAQRIFASFIVTNTFNSGNGGDIDISTNRFASLDGSTVSSSTFSSGNAGNLTIDARESIEVIGFEQANLKTSILTSLTFNSGKGGNLILNTKKLIVADSGRVDASTVGSGAAGSITINASEKVEINGSVPISSIGSRITSSADIADKLLQEVFGIPLVLTGESGAITINTNQLNILDGALLAVKNDGSGNAGKLQVKADSININNQGSISATTTTGGGGDINLNTKSLLLRGNSNISATAAAGDGGNININTQVLAALQNSDITANSEGSFGGKVTINAKGVLGTKLRESLTPKSDITATSGRGAEFNGVVDINTITFNPNFKLVELPTGLADSNQKIVAGCIANRASNFTVIGRGGLPENPSKLFVGNSPIVDLADLVPTSENQQSYIYSTSSEASINNSINNSINKNKKEIVEAKGWILDAQGNIEFVAENPEAIDHSERLQNVNCQIIRSS
>NC_019678.1|WP_015118835.1|3411640_3414175_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MFNHQAIFLGLALAFAFTQVRQAKAQLIPDNTFGKENSLVNSINSLEDRIDGGAIRGSNLFHSFEEFNIGNNRSVYFNNPTAIQNILTRVTGNNASQILGKLGVLGNANLFLINPNGIIFGKDASLDINGSFVGSTASFINFTDGTEFSAVSPEKPLLTISTPIGLGMGNNPGEIRVQGDGHSIVGDGLEFPFVDSSTKGLEVAPGKTIALIGGNIVLEGGLLKTKFGRIELASVASGKVNFTPNLQLSYDNAQSFQDIKLSQEALLDATNSLQNPSDTGNSINQNFADAGSINIKAKKISLTGNSYILLQNQVNIENLPPGTINIDATESLEINDSVIRTQSFLTGKGGDIKVKTKLLMMKDSGIITVSNYGLNSGGDINIEASDSIEIIGSSILDRAPSSITTIAFNSGDGGNINTSTNKLKLIDGGIISSTTFNSGNTGNLTINAREFVKVIGLGSSFTGASFLSSLTLGSGDGGNLTLNTQRLTVKDGGRVDASTGNSGAAGSITINASDKVELAGSGTIREVVIPSLITSSADIADKSLQEILGIPVILNGDSGTVTINTNQLNIADGALLAVKNDGSGNAGKLQVKADSISIKNRGNINATTASGRGGDINLQTQNLLLRDNSNISATAGDGDGGNINIDTQVLAALQNSDISANSEGSFGGKVAINAKGIFGTQFREFLTPESDITATSGKGGEFNGVVDINTITINPNFRLAELPTGLTNSSQQIVAGCSASRASNFTIVGRGGLPESPNQLFTGNIPTVDLLDLIPTSKNMSNDIYYRSSSNSNNNFIHQNKKEIVEAKGWITDTQGNIEFVAKVPRVINNSRGIKAVDCQSLVS
>NC_019678.1|WP_015118836.1|3414246_3415089_-|prephenate/arogenate-dehydrogenase
MIIGIVGLGLIGGSLGLDLKKQGHHVLGVSRRDSTIQRAISLGVVSQASVNMSLLSEAEVVFICTPLGFIIPTLEQLIAYLPSSCVITDVGSVKTPIVKGISPVWENFVGGHPMAGSNDSGIEAARSNLFSDKPYVLTPINTTPAKAITVIENLISQLGVNIHYCSPEEHDKAVSLISHLPVMASASLIAACDKETDSQVHQLAQKFASSGFRDTSRVGGGNPELGVMMAKYNREALLMSLQNYRSNLDELVQLIEREDWTTLEQILHSTQQARSKYIKE
>NC_019678.1|WP_015118837.1|3415282_3416842_+|pentapeptide-repeat-containing-protein
MNVDKFLEKYALGFTDFSGVELPEANLCGVKLSGIDLSHANLSIVNLSGANLTKANLSYAQLNVARLSGAYLEGANLTKASLNVANLIRANLNNAQLVQASLIRGELIRADFSRANLREANLSNADLREATLRHAVLRGANLNQACFKGASLVAANLEQATLNSTDLVRADLSGANLREAELRQVNMFRANLCGANLCDANLRWADLRGANLSWADLSGAKLSGANLTGANLSNANLTNTSLVHADLTEAKLIQAEWVGADLTGATLTGAKLYGTSRFGLKTDMLICEWVDLSPKGDRSIIHNLNAEDSGDFFNETPPTIRIIIDRPLDPEANFALAGAYFQITQKYQGLKQPPSMEIGRRRTVFTFRVDSDESLFPVAYMAILPFKDAAPTQKSIYTAIEMIARKDIDERLISAQKIHQLTILLEQAMQNVNLIKDATKILGIAAKLNFFQAPTQTILTNSSAKNLIINDNPHFGKRLIDHPQIEADLYEDELSELAKSRQPTLAMVEGFFKGFHYIN
>NC_019678.1|WP_157229414.1|3417181_3417751_+|DUF1517-domain-containing-protein
MMGRTRYVVCRILLHLSGSEVAPILGVLNRSASEAIDAEGDMEVMGEELVSVCENLLQYDESWMSAANEGDVFWKEEDAGDYFQELFTDSAQRYLSEPPANYSNSDESFSVPVTRNVVVMITVAYEGEVPQLEDDLSNIAALQEALKALIDLNYKNKLRAVQVHFSPAQLGDELTNDQLLQHFTELIPL
>NC_019678.1|WP_015118839.1|3417899_3418805_+|hypothetical-protein
MTILRKFTAVFLALSLCFTTVACGGGTTTSTPQARNVTRTTTNTRISDGEYPVQQASYNDADGEYTLFLLNSPTPTFKTDKLQMARLTEEQIKEGKSNYLKVENGQPALYLTPDFKIEYTQNVTETRTDPDTGQQRTVVVQRNNGFWAPFAGAVAGQAIGSLLFRPQYYVPPAYQPGRSVYTGFGGYGNSYDVAVDRYRQRYNEPPAAVRNRTTFRTTGNARRRNRGNSGFGTNRSTTPRTSTGNSRSTGSGFGSSTLKQSGKSRSVRNRPSNSSFGSGTRSRSTRSRSRSGGFGSGRRRR
>NC_019678.1|WP_015118840.1|3418974_3420036_-|3-deoxy-7-phosphoheptulonate-synthase
MIIVMKVGSPEQEVKRISEEMVNWGLTPEKIVGQHKVVIGLVGETASLDPLQIQEVSPWIEQVLRVEKPFKRASRQFRHGEASGIVVNTPDGEVTFGENHPLVVVAGPCSVENEEMIVETAQRVKAAGAKFLRGGAYKPRTSPYAFQGHGESALELLAKARVASGLGIITEVMDAADLDKIAEVADVVQVGARNMQNFALLKKVGAQPKPVLLKRGMSATIEEWLMAAEYVLASGNPNVILCERGIRSFDRQYTRNTLDLSVIPVLRKLTHLPVMIDPSHGTGLSELVPSMAMAAIAAGCDSLMIEVHPNPAKALSDGPQSLPPERFDSLMQELSVIGKAVGRWEQAGLVVSG

Crispr_ID: NC_019678_15

• CRISPR_ID: NC_019678_15
• CRISPR_location: 4185447-4185550
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 1 spacers

Consensus repeat of NC_019678_15

Consensus_repeat	Method
TCTTCGGTGCGCGTTCCTGCTTTTTG	CRISPRCasFinder

spacers of NC_019678_15

>15.1|4185473|52|NC_019678|CRISPRCasFinder
CAGTGCTAAAGCTTGTTGCTTTTCTTTGACTGCTGCCTTTAATTGCTCGATA

CRISPR arrays and Neighbor proteins around NC_019678_15

CRISPR arrays

The CRISPR arrays of NC_019678_15

>merge|NC_019678|15|4185447-4185550|CRISPRCasFinder
TCTTCGGTGCGCGTTCCTGCTTTTTGCAGTGCTAAAGCTTGTTGCTTTTCTTTGACTGCTGCCTTTAATTGCTCGATATCTTCAGTGCGCGTTCCTGCTTTTTG

>NC_019678|15|14|4185447-4185550|CRISPRCasFinder
TCTTCGGTGCGCGTTCCTGCTTTTTG	CAGTGCTAAAGCTTGTTGCTTTTCTTTGACTGCTGCCTTTAATTGCTCGATA
TCTTCAGTGCGCGTTCCTGCTTTTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015119400.1|4195435_4196779_+|tyrosinase-family-protein	unknown	unknown	gnl|CDD|365987
NC_019678.1|WP_015119383.1|4173347_4175207_+|CAAX-amino-protease	unknown	unknown	gnl|CDD|226857
NC_019678.1|WP_015119401.1|4196911_4197673_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_019678.1|WP_044291920.1|4182731_4183403_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NC_019678.1|WP_157229427.1|4183445_4184660_-|FtsX-like-permease-family-protein	unknown	unknown	gnl|CDD|182528
NC_019678.1|WP_015119381.1|4170496_4171807_-|hypothetical-protein	unknown	unknown	gnl|CDD|373105
NC_019678.1|WP_015119384.1|4175650_4176289_+|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NC_019678.1|WP_015119389.1|4182210_4182486_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119396.1|4190066_4191521_+|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|273593
NC_019678.1|WP_083894073.1|4176457_4177366_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|225117
NC_019678.1|WP_015119393.1|4186911_4188039_+|YHYH-protein	unknown	unknown	gnl|CDD|379520
NC_019678.1|WP_015119398.1|4192822_4193473_-|Leucine-Rich-Repeat-(LRR)-containing-protein	unknown	unknown	gnl|CDD|275380
NC_019678.1|WP_015119395.1|4189386_4190070_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_019678.1|WP_015119394.1|4188069_4189182_+|YHYH-protein	unknown	unknown	gnl|CDD|379520
NC_019678.1|WP_015119387.1|4180689_4181217_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119386.1|4179534_4180635_+|alkene-reductase	unknown	unknown	gnl|CDD|239243
NC_019678.1|WP_015119399.1|4193991_4194927_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379228
NC_019678.1|WP_015119397.1|4191506_4192772_-|hypothetical-protein	unknown	unknown	gnl|CDD|275380
NC_019678.1|WP_157229293.1|4194923_4195085_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119382.1|4172283_4173180_-|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270406

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015119400.1|4195435_4196779_+|tyrosinase-family-protein	gnl|CDD|365987	pfam00264, Tyrosinase, Common central domain of tyrosinase. This family also contains polyphenol oxidases and some hemocyanins. Binds two copper ions via two sets of three histidines. This family is related to pfam00372.	3.46847e-42
NC_019678.1|WP_015119383.1|4173347_4175207_+|CAAX-amino-protease	gnl|CDD|226857	COG4449, COG4449, Predicted protease of the Abi (CAAX) family [General function prediction only].	0
NC_019678.1|WP_015119401.1|4196911_4197673_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	8.65469e-29
NC_019678.1|WP_044291920.1|4182731_4183403_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	3.44476e-119
NC_019678.1|WP_157229427.1|4183445_4184660_-|FtsX-like-permease-family-protein	gnl|CDD|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	1.78438e-64
NC_019678.1|WP_015119381.1|4170496_4171807_-|hypothetical-protein	gnl|CDD|373105	pfam14516, AAA_35, AAA-like domain. This family of proteins are part of the AAA superfamily.	1.52747e-173
NC_019678.1|WP_015119384.1|4175650_4176289_+|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	9.74455e-64
NC_019678.1|WP_015119398.1|4192822_4193473_-|Leucine-Rich-Repeat-(LRR)-containing-protein	gnl|CDD|275380	sd00033, LRR_RI, leucine-rich repeats, ribonuclease inhibitor (RI)-like subfamily. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	6.83832e-31
NC_019678.1|WP_015119396.1|4190066_4191521_+|HAMP-domain-containing-protein	gnl|CDD|273593	TIGR01386, Probable_sensor_protein_PcoS, heavy metal sensor kinase. Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.	7.57157e-56
NC_019678.1|WP_083894073.1|4176457_4177366_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	5.29088e-23
NC_019678.1|WP_015119393.1|4186911_4188039_+|YHYH-protein	gnl|CDD|379520	pfam14240, YHYH, YHYH protein. This domain family is found in bacteria, eukaryotes and viruses, and is typically between 141 and 198 amino acids in length. There is a conserved YHYH sequence motif.	3.26582e-13
NC_019678.1|WP_015119395.1|4189386_4190070_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.80033e-88
NC_019678.1|WP_015119394.1|4188069_4189182_+|YHYH-protein	gnl|CDD|379520	pfam14240, YHYH, YHYH protein. This domain family is found in bacteria, eukaryotes and viruses, and is typically between 141 and 198 amino acids in length. There is a conserved YHYH sequence motif.	2.28411e-15
NC_019678.1|WP_015119386.1|4179534_4180635_+|alkene-reductase	gnl|CDD|239243	cd02933, OYE_like_FMN, Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Members of OYE family include 12-oxophytodienoate reductase, pentaerythritol tetranitrate reductase, morphinone reductase, and related enzymes.	0
NC_019678.1|WP_015119399.1|4193991_4194927_+|GNAT-family-N-acetyltransferase	gnl|CDD|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	2.80129e-10
NC_019678.1|WP_015119397.1|4191506_4192772_-|hypothetical-protein	gnl|CDD|275380	sd00033, LRR_RI, leucine-rich repeats, ribonuclease inhibitor (RI)-like subfamily. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	4.84003e-40
NC_019678.1|WP_015119382.1|4172283_4173180_-|amino-acid-ABC-transporter-substrate-binding-protein	gnl|CDD|270406	cd13688, PBP2_GltI_DEBP, Substrate-binding domain of ABC aspartate-glutamate transporter; the type 2 periplasmic binding protein fold. This subfamily represents the periplasmic-binding protein component of ABC transporter specific for carboxylic amino acids, including GtlI from Escherichia coli. The aspartate-glutamate binding domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.08069e-82

Protein sequences

>NC_019678.1|WP_157229427.1|4183445_4184660_-|FtsX-like-permease-family-protein
MAVEALWNNKLRTMLTMLGIIIGITAVIAVTAIGQGTQKATEQRLQSLGSDILQVRSGAARSGRVRQGAGSATTLTLEDAEAIAQQVLGVERVSAFLEQNAQVVYAQNNNSLTIIGTDINYPDVRNTHPQTGRFFTQEEVDAGKPVAVLGPTARDELLGSGSSAEGSQIRIQGQIYEVIGVMETKGAQGRQNPDELIYIPLTNMSARLVGNNSVKGIAVRGIYVKVKSQDRLDAAEYQTTNLLRVRHGIFPAKDHKDDFRIINSADIIETLTSTSKLFTIMIVAVAAISLIVGGIGIANIMLVSVVERTREIGIRKAVGATNSAILSQFLAEAVIIAAMGGAIGICLGIVIGFGASNSFKFPLVISLWSILFGFGLTFIIGLLAGVIPARNAARLDPIEALRSD
>NC_019678.1|WP_044291920.1|4182731_4183403_-|ABC-transporter-ATP-binding-protein
MIWMEGIEKTYCLGESKIPILKGINLSIEEGEYVAIMGMSGSGKSTLMNIIGCLDRPTSGYYVLEGRNLTTLTNDELAYIRNQHIGFVFQQFNLLPRSTALENVMLPMVYAGISKSQRKKRAESALIRVGLAERMLNRPNQMSGGQQQRVAIARALVNRPKLVLADEPTGALDTQTSGEVMNLLTELNSQGITIVIVTHEPDVANQTNRIIHVKDGLVTHKVT
>NC_019678.1|WP_015119389.1|4182210_4182486_+|hypothetical-protein
MNWNQVSTGILVIASLVTTALPVSASPYRTSNNDYRREKVVDVVDINVNLRGKKKRRVNKKKFKEVCVNKRVRTRRGVRKVRECKLVRIRR
>NC_019678.1|WP_015119387.1|4180689_4181217_-|hypothetical-protein
MKLNQLLTLTAIPALLGTLAFASVNKINAASPSSLTIAQNQPPQGQRRPRRQKPNLKAAAEKLGITEQQLKDALGRPPQPDFAAAASKLGTSEGELKEALGLPENPPELSEGQRPPKPDFKAAAAKLGVTKQQIKEAFGPRPRKDLSAAASKLGISEEELKEALGVPENPPERPE
>NC_019678.1|WP_015119386.1|4179534_4180635_+|alkene-reductase
MTSHLLSDFNLKNLSLKNRLVMAPMTRSRAGAERMPNALMAEYYAQRSGAGLIISEGTTISKQANGWLHTPGIYTPEQTEAWKQVVDAVHAKGTPIFLQLWHTGRASHSSFQENNQLPVAPSAIRIESSEAHTPDGKKPHETPRALETAEVSQVVEDYRQAAANAKQAGFDGVEIHGANGYIIDEFLQSKTNQRSDKYGGSLENRYRFLKEIIESVLTVWDAGRVGVRLSPNGNYNDMGSPDYRETFTYVIEQLNQYGLAYLHVLDGLGFGFHELGEPMTVAELRKIYNGTLIGNCGYDKQSAEKAIAANEADLIAFGRPFISNPDLVERFANNWELNADPETAIWYSFEAEGYTDFPTYQDKVAV
>NC_019678.1|WP_083894073.1|4176457_4177366_-|helix-turn-helix-transcriptional-regulator
MLFDCNNLVALLIQAGSKPRNIYQLNNVYLEYHQHPPHETPEHYPKQHVLAIQTVGRVEAERRLDGSLKQEQVNVGDVCIVPAHTPHWIHSAGEQELILLSLKPSFLKRIAYESITSDIELLPHFAKPDPLIYQIGLSLKTALQTNPLESRFYADSLITALAAHLLQFYTARKPKINADVGSNSQIGQAIEYIHEHLNEDLSLETIASLLDISKYHFCRLFKQTTGLTPWQYVIKVRVEAAKRLLAKPELSIVQISRQLGYSSSSFSLFTRGTRKRYFRNGRLLHCWFNSHRFNLENQTLEI
>NC_019678.1|WP_015119384.1|4175650_4176289_+|histidine-phosphatase-family-protein
MALNLYFLRHGETTFSQSGDFCGETNAELTPEGEHMAESFADVYQKLKWKAVYASPMKRTVATAKPFCDATGIDMQLRDGLREGSYGEWEGKSKEFAQEHYAENYINWLTEPAWNAPKGGETAVDIANRSMPVIAEIQEKHPEGNVLVVSHKATIRIMLCSLLGIDLGSYRYRINILVASVSMVKFDVHGPLLEFLGDRNHIPEDIRTRKGT
>NC_019678.1|WP_015119383.1|4173347_4175207_+|CAAX-amino-protease
MNYIIIFVVCVTVGFIIYCINKKSLQSKSSNYKISSESPLFAPEYYPINQTVDLKLYQPVAEWSGRLIFINEHENERFVKFELQNTPNSYRHLLGKVVKLQWSDDRKVQEYVKRMSFDVKFTNQAKKSHQKGLVHPVRLDGLAQVDSLESLAGARPMNDVCVMLLNPEVQADAKGETQLIIEREPIEIAGRFVALVQFQARIEPQSDLFKVHHYNNATRSFSQGIEEIICIPQVPQDIKGIPRSSNRDIEKSPANIEGWYIYGAPNAEGIFVVQAIEPRALVKIEPQKVITKSPKIFEYLNKRIWAKTKLQKGNYDTVLLAPERANIKGALSEWQLGDKALVIHLFGGIGGQKAEASSWLPVPGHFSYGIAEVVKDKITSELRFDIIYHQVYCHNPEAIIAGSLTWAAYMGSLWRGWLGTRPVSDILIKYEPITTDYDFGGIKVSPLTEFIEELREITARYRLGDGTGASLISPTASCVQDSNQALYATIHDIQNLVKSNPAINQWLQKHPNDKQTQYFNELISLGDILEKQLIPLGVVRRDWQQNAKDLFGTNSKNENIFTTAIKMLKSWRTVLPKRAQDEIVKIFLKQKATAWVLRTNQVGGYDDTIAPVAPTMIFK
>NC_019678.1|WP_015119382.1|4172283_4173180_-|amino-acid-ABC-transporter-substrate-binding-protein
MSKQIAIAALSLLFTAALPGIASAETVMQKVKRTGVLTAGTSKDAFPFAYKNKQGELIGYSVDMLKLIQQQLEKELGKKVKLQLVTLPPAGRIPNIVNRKVDIVCDASSFTWERNKNVDFSFSYGATGTNLLVKKASNLGSPKSLVGKKIGVLAKTTNENAIKRAQPQAKLVYLKDRWQGYTALRQGKIDAFADDGILLEAWLGRSKNYNQFKVVPDRPYSREGIACMIPENNSDFLDTVNYTFYGFMQGFVNNESKYVTIFDRWFGPRGAIPLNRDLRELTVETMRIVIDSHQDVRQ
>NC_019678.1|WP_015119381.1|4170496_4171807_-|hypothetical-protein
MEAAKQRRRRGIVLTATGLKRLQTAIQSAQLQENDGSRFTQEELSSRIGVSTNTLSRLWSLKTGVDSRSVKLCFSAFDLELTGSDYRAWEEVEQSEGAEYPNGPLSLYSKLYICRPPIEQLVNQEISRPGCLVRIKASKGMGKTSLKLRLLDYAKSLSYYTLHLDLNLVDTDKFLNIDVFLRWMCRMVSKSLNIEAQIDEFWDEEIGSKLSCTLYFQAHILESLNSSLVLSFNELNRVFEYPELAQEFLPLLRSWHENSQYNQAWQKLRLVVDYSTDIYVPLDVNHSPFNIGLPIQLPEFTLEQVEELATRYELDWQAGNQAQKLIEVIGGQPSLVNIALYHLSQEELTLEQLLEEATTERGIYRHHLREKLDYLRKNTNLAAVFSQMLTAQNSVSLPPTVAYKLESIGLIKLTPDGAIISRELYRSYFSQYLNAE
>NC_019678.1|WP_015119393.1|4186911_4188039_+|YHYH-protein
MKVLIIILTGVIAAGSSFSCTKQKPIASSTNMSEISDNRVKNQDSGEEAETALTQYETLGMTFLKNAIVKDITTKNCTLVDGTQTTCQSITVSGYPSNYEAGPFCPRTTADSKETTGIWLDGENIYDLDGKFIMKLPEIYDDEKFILYDSNNNVNVTDTKEEFDGAAKPQVEEEYKYNCVEGKIEWLEGGSPIQTTVEIPANPVKSDTVTNLGRNKVGVTINGVVIDSPAPVQAILSAYTIAAFDDCGGHINPVIGYHQHGITGCFGVESKVDGETKLVGYAMDGFPIHSTYEESNQTPELDECGGHEVEGLGYHYHANKAAKNSVISCFHGTLVKGQQGRRGGRPRRPPQGQRPPGNMTPRKGISPVVLPPKQD
>NC_019678.1|WP_015119394.1|4188069_4189182_+|YHYH-protein
MQVRRLPILILTAVFAASSSLSCTQQTPNSSSANTIDASKRNGDEETKNAQSSPTATDCTTYKKAFGLHLDSEAINCTADSLEVTATGLPDLTSRSSEDVPMVGIKSWIQRVAIPYDYQWRIPLKPQWLDEPVEASPRGPIAVAVDGVPIFHYERRPDVSTSLDNYEERNDTVVQGELDQCGGHAGQGEDYHYHYAPVCLMDKHNPELPIAFALDGTPIYFGEGGDEYYGRGRYSDLSYLPDQELDECNALQLPDGSYVHYTTKTPPYVVGCHHGFFDSKLQIEPPTFDALAQRTSSPFGGSYGEPVSTLITDFKKNEDGEYRLGFNSLTTPGVTSAVVYRKTSSDCWEFEYQKVAGETVQTTTACRHQH
>NC_019678.1|WP_015119395.1|4189386_4190070_+|response-regulator-transcription-factor
MNVLFVEDEAKIADFVRAGLKEQGFTVDYCDNGNEGCLLALENEYDAIILDIMVPGKDGLSILKQLRQKGKNTPVILLTARNELDDRLQGLNLGADDYIAKPFFVEELVARIHAVIRRTVGERQNYIAVGALKLDRITREVTCNQKAIELTTREFNLLEYLMRSPERVFTRTQILEHVWGYDFNPNTNVVDVCIQRIRKKIDPINKGEWIESIRGVGYRFRQADTHS
>NC_019678.1|WP_015119396.1|4190066_4191521_+|HAMP-domain-containing-protein
MKLASFRLRIALFSSVLAGSALIGFGGISWLQIYNANISRLDAQIINQLMRGNGPPKRDITQLYQKQRWKLYSDSLSDVLGANTKIPTALLVLDKEGNKLYQTQEIILDRDLHRLLNKQLKLTNPSPLITARNLSSKELPPAPLPILLTTESTETGTWRIGTAKFRKIQIAVAVNLEVVNQEMAAITNIFLISIPGVLLLIAVGGWLLSGSVLRPINQLTSEIQLVSAKGLDRRIPLDKTDVEFVELIQVFNQMLERLERSFHQASRFSGDAAHELKTPLTILQGELERTLQQVTHGSEVQQRLSYLLDEVHRLNGIIRKLLLLSLADAGKLSLYLVKVDISELLFQMLEDMEMLAPHLRVQTNIAKGLKVKGDKDLLMQVLQNLISNAIKYNLADGWIKVDAFANQNSLQVTIVNASEGIKDENRTRIFDRFHRGDPSRNRKVEGIGLGLSLAREIVRAHHGELILNPASEGETSFSLCLPVV
>NC_019678.1|WP_015119397.1|4191506_4192772_-|hypothetical-protein
MMNEEELLKIIEQTEKEGLTTLNLSGEDLHFLPKEIKKLPNLEYLYLGNNHLTELPEEIEQLKKLKLLDLSNNLIKSFPLGIAKLTNLKVLSLDDNYLNNLPEEIGNLNNLEYLDLSNNQLNQLPPEFGKLIKLQELCLEGNQLTSLPCEFGQLSKLKELDLLENELTYLPEEFGKLINLQKVDLGNNKLITLPKEIGQLANLELLEIGENQLTSLPPELGKLSKLKQLNLSVNQLSDLPLSQAKLINLKTLYLCSNQFTKLPAEISRLTNLKSLYVIQNQLNNLTPEIGQLSNLELLDISENKLNSLPTEIEKLTSLRYFILNVNHLSNLPKEIGHLTNLVTLNLQENQLTTLPTEIEKLMNLEYLFLSENKISNLPIEIKQLTKLKHLDLSKNPISIPPEILKEKPQKILNCYFTSHHR
>NC_019678.1|WP_015119398.1|4192822_4193473_-|Leucine-Rich-Repeat-(LRR)-containing-protein
MTEEELLEQIEQAAREGLKTLNLARQSIKLLPKEIGQLTNLKVLNLDENQLITLPREIGNLTNLEYLCLSRNKLSSLPSEIGKLINLEELDLEENQINSLPPEIGKINNLQCLDLESNHLSELPREIGQLTRLKSLYLSGNQLNELPSDIGQLTRLHTLYLGGNQLTSLPVEIKKLTGLIEIELSKNPISIPLGVLKKSPKQIINFYFKLQNHGSN
>NC_019678.1|WP_015119399.1|4193991_4194927_+|GNAT-family-N-acetyltransferase
MQIKIRNLQEVEIPEADRIFRLAFGTFIGLPNPLEIFGDADFITYRWKTDPSAAFAAEINGKLVGTNIACRWGNVGFFGPLSVHPDYWNQGVAQKLIAAVMSKFEQWDVKQANLFTFADSSKHHVLYQKFGFYPRFLTFFMAKSIQKTSEESASGYSQLQPELRRQSLDACFEITNEIYPGLDVSSEIIAVYEHNLGDTVLLWEDNQLIGFAVCHCGANTEAGSNDCYIKFAAVKPGINVAANFEKLLKSCEYFTENQGLNRLVAAVNISHEQAYKILFARQFRTESIGVTMHNPSPEYNKVDVFVLDNWR
>NC_019678.1|WP_157229293.1|4194923_4195085_-|hypothetical-protein
MGSLNSGHEVKELTKSNLQSAFGVSSDEDVRRSPRGVSQQLIKNQEAICCIKS
>NC_019678.1|WP_015119400.1|4195435_4196779_+|tyrosinase-family-protein
MKHLPKILAKMTVGMAIVFSISQAPAIAASLVRKNVIDLTPQEKADFVDAIKTLKTTPGTNDNQVSIYDEIVAIHTGAMAFTPKQLGGLVTLPQDTPATGQQAGVDAAHGNSAFLPWHREYLNRFEKALQSVNPNVTIPYWDWTDPRSVDAIFQPDFLGTNGSGQPREIRGRDELLEGGPLQSGNFSAADGWNLIPDLHTNVVTGETLGSSIVRYLPPDSNPPEQQLPLDNARIDRLLQSDNYNRFRLALEGRTFIDENGNEQICTLPCTHNLIHALVGGGFVDQPPDLSDLNPPAEPPPLEIVGTMNNVPGSPNDPVFWLHHSNVERLWAEWQNNGRQGSEFYAELGTQPQGHDLNDRMWPWDGGASIPGSVSDIDITPYLPSIAPEDIVKVSDTLNLSDYHYTYDTIVNKGQVIKVPETNSIFGLFGLGVVGAICLRRRKGFFGS
>NC_019678.1|WP_015119401.1|4196911_4197673_-|class-I-SAM-dependent-methyltransferase
MKQWYEELFENYAVKYDKESFTQGTIGECDFIEKEIEYNKEAKILDIGCGTGRHSIELAKRGYKVIGIDLSESMLRRAKQKAGEEDVEVKFEKHDARKIPYLDQFDLVIMLCEGGFSLMETDEMNFQILQNAANALKSKGKFIFTTLNGLFPLFNSVKEFLNSEAESGNATYDNNSFDLMTFRDVSKICIEDDLGNQKEIQSVERYYVPSEITWLLKTLNFQPVDIFGAKLGAFSRGDKLSTKDFEMLVIAEK

Crispr_ID: NC_019678_16

• CRISPR_ID: NC_019678_16
• CRISPR_location: 4246644-4247202
• CRISPR_type: TypeIII
• Repeat_type: A:N
• Spacer_info: 7 spacers
• Cas_protein_info: PD-DExK,cas10,csm3gr7,csx10gr5,csm2gr11,csx19,csx21

Consensus repeat of NC_019678_16

Consensus_repeat	Method
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	CRISPRCasFinder
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	CRT
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	PILER-CR

spacers of NC_019678_16

>16.1|4246679|39|NC_019678|CRISPRCasFinder,CRT
GCTATTTTCGGTTCTATTGCTACTCTAGGTATATTTGCA
>16.2|4246753|43|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TAAAGTGTGTTTCCGGCACCGTTGGGTGCAATGGTGACTTAGG
>16.3|4246831|39|NC_019678|CRISPRCasFinder,CRT,PILER-CR
GTTTAGTTGGTGGAAGTTATTTTATCCAAAATCTTACTA
>16.4|4246905|43|NC_019678|CRISPRCasFinder,CRT,PILER-CR
CCATTCGCACTAATATTAGAGTAGATGGAAATACTAACGGCAG
>16.5|4246983|40|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TTTTTGAAAACGCGTCGCAAAGCGACATTGAAAGAGTAAA
>16.6|4247058|36|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TACATTTAGCTCTGGGGTTATGATGCCTTACGCTGT
>16.7|4247129|39|NC_019678|CRISPRCasFinder,CRT,PILER-CR
ATTTTAGCAGAACGCAAGCCGCTCAAAACAGGTCCAAAA

CRISPR arrays and Neighbor proteins around NC_019678_16

CRISPR arrays

The CRISPR arrays of NC_019678_16

>merge|NC_019678|16|4246644-4247202|CRISPRCasFinder,CRT,PILER-CR
ATTGTTATCCCCTCACGGGGTTAAAGATTAAAAACGCTATTTTCGGTTCTATTGCTACTCTAGGTATATTTGCAGTTTCCATCCCCTGACGGGGTTAAAGATTAAAAACTAAAGTGTGTTTCCGGCACCGTTGGGTGCAATGGTGACTTAGGGTTTCCATCCCCTGACGGGGTTAAAGATTAAAAACGTTTAGTTGGTGGAAGTTATTTTATCCAAAATCTTACTAGTTTCCATCCCCTGACGGGGTTAAAGATTAAAAACCCATTCGCACTAATATTAGAGTAGATGGAAATACTAACGGCAGGTTTCCATCCCCTGACGGGGTTAAAGATTAAAAACTTTTTGAAAACGCGTCGCAAAGCGACATTGAAAGAGTAAAGTTTCCATCCCCTGACGGGGTTAAAGATTAAAAACTACATTTAGCTCTGGGGTTATGATGCCTTACGCTGTGTTTCCATCCCCTGACGGGGTTAAAGATTAAAAACATTTTAGCAGAACGCAAGCCGCTCAAAACAGGTCCAAAAGTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC

>NC_019678|16|15|4246644-4247202|CRISPRCasFinder
ATTGTTATCCCCTCACGGGGTTAAAGATTAAAAAC	GCTATTTTCGGTTCTATTGCTACTCTAGGTATATTTGCA
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	TAAAGTGTGTTTCCGGCACCGTTGGGTGCAATGGTGACTTAGG
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	GTTTAGTTGGTGGAAGTTATTTTATCCAAAATCTTACTA
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	CCATTCGCACTAATATTAGAGTAGATGGAAATACTAACGGCAG
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	TTTTTGAAAACGCGTCGCAAAGCGACATTGAAAGAGTAAA
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	TACATTTAGCTCTGGGGTTATGATGCCTTACGCTGT
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	ATTTTAGCAGAACGCAAGCCGCTCAAAACAGGTCCAAAA
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC

>NC_019678|16|4|4246644-4247202|CRT
ATTGTTATCCCCTCACGGGGTTAAAGATTAAAAAC	GCTATTTTCGGTTCTATTGCTACTCTAGGTATATTTGCA
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	TAAAGTGTGTTTCCGGCACCGTTGGGTGCAATGGTGACTTAGG
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	GTTTAGTTGGTGGAAGTTATTTTATCCAAAATCTTACTA
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	CCATTCGCACTAATATTAGAGTAGATGGAAATACTAACGGCAG
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	TTTTTGAAAACGCGTCGCAAAGCGACATTGAAAGAGTAAA
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	TACATTTAGCTCTGGGGTTATGATGCCTTACGCTGT
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	ATTTTAGCAGAACGCAAGCCGCTCAAAACAGGTCCAAAA
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC

>NC_019678|16|4|4246718-4247202|PILER-CR
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	TAAAGTGTGTTTCCGGCACCGTTGGGTGCAATGGTGACTTAGG
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	GTTTAGTTGGTGGAAGTTATTTTATCCAAAATCTTACTA
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	CCATTCGCACTAATATTAGAGTAGATGGAAATACTAACGGCAG
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	TTTTTGAAAACGCGTCGCAAAGCGACATTGAAAGAGTAAA
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	TACATTTAGCTCTGGGGTTATGATGCCTTACGCTGT
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC	ATTTTAGCAGAACGCAAGCCGCTCAAAACAGGTCCAAAA
GTTTCCATCCCCTGACGGGGTTAAAGATTAAAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015119424.1|4229756_4230140_-|DUF559-domain-containing-protein	unknown	unknown	gnl|CDD|238509
NC_019678.1|WP_044291936.1|4232511_4234041_+|glycerol-kinase-GlpK	unknown	unknown	gnl|CDD|198361
NC_019678.1|WP_015119433.1|4243082_4245710_+|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl|CDD|181933
NC_019678.1|WP_015119438.1|4251576_4252833_+|CRISPR-associated-RAMP-protein-Csx10	csx10gr5	cd09700_csx10gr5_CAS-III-D	gnl|CDD|131722
NC_019678.1|WP_015119435.1|4247550_4248093_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119436.1|4248473_4250864_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cls000742_cas10_CAS-III	gnl|CDD|274208
NC_019678.1|WP_015119442.1|4255302_4255797_+|hypothetical-protein	csx19	cls000059_csx19_CAS-III-D	unknown
NC_019678.1|WP_015119437.1|4250863_4251580_+|RAMP-superfamily-protein	csm3gr7	COG1337_csm3gr7_CAS-III-D	gnl|CDD|224256
NC_019678.1|WP_015119430.1|4238200_4239919_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|223503
NC_019678.1|WP_015119444.1|4256888_4257566_+|hypothetical-protein	csx21	mkCas0116_csx21_CAS-III-A:CAS-III-D	unknown
NC_019678.1|WP_015119431.1|4240127_4241837_+|flavoprotein	unknown	unknown	gnl|CDD|223503
NC_019678.1|WP_015119443.1|4255821_4256889_+|RAMP-superfamily-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NC_019678.1|WP_015119425.1|4230833_4232273_+|DUF4114-domain-containing-protein	unknown	unknown	gnl|CDD|379190
NC_019678.1|WP_015119439.1|4252829_4253300_+|hypothetical-protein	csm2gr11	mkCas0063_csm2gr11_CAS-III-D	unknown
NC_019678.1|WP_015119432.1|4242292_4242472_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119441.1|4254328_4255306_+|RAMP-superfamily-protein	csm3gr7	COG1337_csm3gr7_CAS-III-D	gnl|CDD|224256
NC_019678.1|WP_015119434.1|4245930_4246551_-|hypothetical-protein	PD-DExK	mkCas0061_PD-DExK_CAS-I:CAS-III	unknown
NC_019678.1|WP_015119440.1|4253347_4254211_+|CRISPR-associated-RAMP-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187814
NC_019678.1|WP_044290992.1|4234649_4236599_-|heavy-metal-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319849
NC_019678.1|WP_044291938.1|4236678_4237851_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224993

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019678.1|WP_015119438.1|4251576_4252833_+|CRISPR-associated-RAMP-protein-Csx10	csx10gr5	cd09700_csx10gr5_CAS-III-D	3.1e-129	426.5	0.0
NC_019678.1|WP_015119443.1|4255821_4256889_+|RAMP-superfamily-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	5.2e-43	142.6	5.3
NC_019678.1|WP_015119441.1|4254328_4255306_+|RAMP-superfamily-protein	csm3gr7	COG1337_csm3gr7_CAS-III-D	1.4e-55	183.2	0.0
NC_019678.1|WP_015119439.1|4252829_4253300_+|hypothetical-protein	csm2gr11	mkCas0063_csm2gr11_CAS-III-D	7.2e-60	195.9	1.7
NC_019678.1|WP_015119442.1|4255302_4255797_+|hypothetical-protein	csx19	cls000059_csx19_CAS-III-D	3.9e-48	157.8	2.2
NC_019678.1|WP_015119436.1|4248473_4250864_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cls000742_cas10_CAS-III	2.3e-82	271.9	0.0
NC_019678.1|WP_015119434.1|4245930_4246551_-|hypothetical-protein	PD-DExK	mkCas0061_PD-DExK_CAS-I:CAS-III	4e-66	217.1	1.3
NC_019678.1|WP_015119440.1|4253347_4254211_+|CRISPR-associated-RAMP-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	8.9e-72	235.7	0.0
NC_019678.1|WP_015119437.1|4250863_4251580_+|RAMP-superfamily-protein	csm3gr7	COG1337_csm3gr7_CAS-III-D	9.9e-33	108.3	0.0
NC_019678.1|WP_015119444.1|4256888_4257566_+|hypothetical-protein	csx21	mkCas0116_csx21_CAS-III-A:CAS-III-D	3.4e-67	220.8	12.8

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_044291936.1|4232511_4234041_+|glycerol-kinase-GlpK	gnl|CDD|198361	cd07786, FGGY_EcGK_like, Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases. This subgroup is composed of mostly bacterial and archaeal glycerol kinases (GK), including the well characterized proteins from Escherichia coli (EcGK), Thermococcus kodakaraensis (TkGK), and Enterococcus casseliflavus (EnGK). GKs contain two large domains separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. The high affinity ATP binding site of EcGK is created only by a substrate-induced conformational change, which is initiated by protein-protein interactions through complex formation with enzyme IIAGlc (also known as IIIGlc), the glucose-specific phosphocarrier protein of the phosphotransferase system (PTS). EcGK exists in a dimer-tetramer equilibrium. IIAGlc binds to both EcGK dimer and tetramer, and inhibits the uptake and subsequent metabolism of glycerol and maltose. Another well-known allosteric regulator of EcGK is fructose 1,6-bisphosphate (FBP), which binds to the EcGK tetramer and plays an essential role in the stabilization of the inactive tetrameric form. EcGK requires Mg2+ for its enzymatic activity. Members in this subgroup belong to the FGGY family of carbohydrate kinases.	0
NC_019678.1|WP_015119424.1|4229756_4230140_-|DUF559-domain-containing-protein	gnl|CDD|238509	cd01038, Endonuclease_DUF559, Domain of unknown function, appears to be related to a diverse group of endonucleases.	5.61361e-42
NC_019678.1|WP_015119438.1|4251576_4252833_+|CRISPR-associated-RAMP-protein-Csx10	gnl|CDD|131722	TIGR02674, cas_cyan_RAMP_2, CRISPR-associated RAMP protein, Csx10 family. CRISPR is a widespread repeat family in prokaryotes. At least 45 different protein families occur in prokaryotes only when these repeats are present. This family, a minor CRISPR-associated protein family, seems largely restricted to the Cyanobacteria. It belongs to the RAMP superfamily (pfam03787).	1.06826e-133
NC_019678.1|WP_015119433.1|4243082_4245710_+|DNA-polymerase-III-subunit-alpha	gnl|CDD|181933	PRK09532, PRK09532, DNA polymerase III subunit alpha; Reviewed.	0
NC_019678.1|WP_015119436.1|4248473_4250864_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl|CDD|274208	TIGR02577, thermophile-specific_DNA_repair_system, CRISPR-associated protein Cas10/Cmr2, subtype III-B. This model represent a Crm2 family of the CRISPR-associated RAMP module, a set of six genes recurring found together in prokaryotic genomes. This gene cluster is found only in species with CRISPR repeats, usually near the repeats themselves. Because most of the six (but not this family) contain RAMP domains, and because its appearance in a genome appears to depend on other CRISPR-associated Cas genes, the set is designated the CRISPR RAMP module. This protein, typified by TM1794 from Thermotoga maritima, is designated Crm2, for CRISPR RAMP Module protein 2.	3.64674e-44
NC_019678.1|WP_015119437.1|4250863_4251580_+|RAMP-superfamily-protein	gnl|CDD|224256	COG1337, COG1337, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	4.39345e-37
NC_019678.1|WP_015119430.1|4238200_4239919_+|MBL-fold-metallo-hydrolase	gnl|CDD|223503	COG0426, FpaA, Uncharacterized flavoproteins [Energy production and conversion].	3.25048e-168
NC_019678.1|WP_015119431.1|4240127_4241837_+|flavoprotein	gnl|CDD|223503	COG0426, FpaA, Uncharacterized flavoproteins [Energy production and conversion].	8.98997e-163
NC_019678.1|WP_015119443.1|4255821_4256889_+|RAMP-superfamily-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	2.40975e-17
NC_019678.1|WP_015119425.1|4230833_4232273_+|DUF4114-domain-containing-protein	gnl|CDD|379190	pfam13448, DUF4114, Domain of unknown function (DUF4114). This is a repeated domain that is found towards the C-terminal of many different types of bacterial proteins. There are highly conserved glutamate and aspartate residues suggesting that this domain might carry enzymic activity.	1.72181e-10
NC_019678.1|WP_015119441.1|4254328_4255306_+|RAMP-superfamily-protein	gnl|CDD|224256	COG1337, COG1337, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.75828e-40
NC_019678.1|WP_015119440.1|4253347_4254211_+|CRISPR-associated-RAMP-protein	gnl|CDD|187814	cd09683, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	5.37131e-76
NC_019678.1|WP_044290992.1|4234649_4236599_-|heavy-metal-translocating-P-type-ATPase	gnl|CDD|319849	cd07551, P-type_ATPase_HM_ZosA_PfeT-like, P-type heavy metal-transporting ATPase, similar to Bacillus subtilis ZosA/PfeT which transports copper, and perhaps zinc under oxidative stress, and perhaps ferrous iron. Bacillus subtilis ZosA/PfeT (previously known as YkvW) transports copper, it may also transport zinc under oxidative stress and may also be involved in ferrous iron efflux. ZosA/PfeT is expressed under the regulation of the peroxide-sensing repressor PerR. It is involved in competence development. Disruption of the zosA/pfeT gene results in low transformability. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_019678.1|WP_044291938.1|4236678_4237851_+|MerR-family-transcriptional-regulator	gnl|CDD|224993	COG2082, CobH, Precorrin isomerase [Coenzyme metabolism].	3.21103e-64

Protein sequences

>NC_019678.1|WP_015119434.1|4245930_4246551_-|hypothetical-protein
MSFSSYKTISEVLKTFQITYTEANFMGEAEFNIPDYFREDLETVMREGVVYSSEFAICENIIYPVLKEVWKLYNSKFTLWSHHSLNYNDNLSGFPEYILAKRSSLGKVVFDKPYFILVEAKQDDFEGGWAQCLAEMIAAQRLNEKVEITIFGIVSNGKIWQFGKLEKNNFISNIDIYTIQDLDKIFAAVNYIFQHCESQLDNLIAA
>NC_019678.1|WP_015119433.1|4243082_4245710_+|DNA-polymerase-III-subunit-alpha
MSFVPLHIHSDYSLLDGASQLPALIDRAIELGMEAIALTDHGVMYGAVELIKICKKKSFKPIIGNEMYIINGDITKQERRPRYHQVVLAKNTRGYKNLTKLTSISHLEGVQGKGIFSRPCINKELLKQYHEDLIVTSACLGGEIPQAIMSGRPDVARRVAKWYQDTFGEDYYLEIQDHGSQEDRVVNVEIVKIAKELGIKIIATNDSHYISCNDVEAHDALLCIQTGKKIFEDKRMRYSGTEYLKSAEEMKQLFRDHLPEDVIEEAVSNTLEVADKIEPYKILSPPRTPHFPIPAGHTTETFLEEVAWDGLLEKLNRKSRSEVDKSYTDRLKYELKLIQEMGFPGYFLIVWDYIKFARDSNIPVGPGRGSAAGSLVAYCMGITNIDPVHHGLLFERFLNPERKSMPDIDTDFCIENRDEVIDYVTRQYGKDKVAQIITFNRMTSKAVLKDVARVLDIPYGEADKMAKMIPVARGKPAKLSKMISDDTPEPEFKEKYDNDPGVKHWVDMAIRIEGTNKTFGVHAAGVVISAEPLDEIVPLQRNNDGSVITQYYMEDVEAMGLLKMDFLGLRNLTMIDKTIDLVEKKIGRRIDPYDITSHERKAQKVLARGGDAAKLPNDVRKTYELLEAGELEGVFQLESSGMRQIVRDLKPSNIEDISSILALYRPGPLDAGLIPHFIDRKHGREQIKYEANVLEPILDETYGIMVYQEQIMKIAQDMAGYSLGQADLLRRAMGKKKVAEMQKHREIFIDGSAKNGVSKQIAEALFDQMIKFAEYCLSYDTEVLTEEFGLIPIGKIVEEKIDCTVYSVDVNGNVYSQPIAQWHNRGMQEVFEYELEDGSTIRATKDHKFMTVDGEMLAIDEIFEKGLELKRVGIY
>NC_019678.1|WP_015119432.1|4242292_4242472_+|hypothetical-protein
MYPEKKKLKFPFWQYLNQPLFSEKLILNPHTFAYVYRIELLERCWGRECDAKGQSSSGG
>NC_019678.1|WP_015119431.1|4240127_4241837_+|flavoprotein
MSNSNPRDMQIASIATDTRLIKARSWTRLRFEIEYALAKGSTSNCYLIEGDKTAIVDPPPETFTHIYMEALQKILDLQELDYVIVGHFNPNRVATLKALLERAPQLTFVASVPGAANLRKTFGENTKIIEMRGKETLDLGKGHILRGIPIPSPRWPSGLATYDQQSQILYSNKLFGTHVCGEEVFDEDWDILKEDQRYYYDCLMAPHAPHVKAALEKISDLPVRMYATVHGPLVRYGLIELKKAYQQWSVSQTEREVTVALLYASAYGNTSTLAQAFGLGLTKGGVAVESINCEFADPDDIRAAIEKSDGFIIGSPTIGGNAPTPIHTALGIVLSVGDTSKLAGVFGSYGWSGEAFDLIEGKLKDAGFKFGFDTFKARFKPSDKTLKECEETATDFAQTLRKARKLRIVQPTATPMEQAVGRIVGSVCVLTAKQGEVATGMLGSWVSQATFDPPGISLAIAKDRAVETLLYPGSKFVLNIIGEGNQQDYVKHFRKSFAPGEDRFSNFSTTEADNGGIILTEAIAYIECSASKRMECGDHWVIYATVDNGKLLQADTATAIHRRKAGNHY
>NC_019678.1|WP_015119430.1|4238200_4239919_+|MBL-fold-metallo-hydrolase
MVAVNENAQKRLTIQTVEIAPNTTAIRSLDWDRDRFDIEFGLQNGTTYNSYLIRGERTALVDTSHTKFREQYLETLKSLVNPKEIDYIIVSHTEPDHSGLVEDVLQIAPRATVLASKVALQFLENLVHDPFSKRIVKTGDSVDLGDGHEIQFVSAPNLHWPDTIFSFDKKTQTLFTCDAFGMHYCSDDTFDVNLEAIEPDFKFYYDCLMGPNARSLLNAMKRMGDLGKIKIIANGHGPLLYHNLDTLKECYQSWSQKQAKTETIIGLYYVSEYGYSDRLAQSIGHGIQKTGIGVEMLDLTTTDLQEIQELAGRAAGIIIGMPPSHNTAAQAAISSLLAVVKNKQVIGLYESYGGDDEPIDTLRRKFLEHGVREAFEAIRIKEEPNNDVFRAADEAGNEMGQLLVRERNIKHLKSIDADLEKALGRISNGLYVVTTKKGDIKGAMVASWIAQASLQPLGFTVAIAKERGIESSLQIGDKFVLNVLEEGNYHDLKKHFLKRLLPGVDRFEGVKTQTAKNGSPILTDALAYMECEVKTTMECSDHTLLYCTVSEGRISDPDGMTAVRHRKVGTYY
>NC_019678.1|WP_044291938.1|4236678_4237851_+|MerR-family-transcriptional-regulator
MAKNYQTESAQNSKEDSKNKHLTIKQLTQEVGGGLTPRMVRHYHKLGLVPEAERSEGNYRLYTDKSVQHLRRIVALKSQGFQLEHIQKLLATYPESDNFDSLTTQLQQQYQSVIEQLSRLRKTASALEGLLGRDKHCQRIQAEAIAELRHLEIESTLGTKKLEQLWQGLDAACDAHPEDLSESLQQLLPDLSNKNEIERDLLGKLVLASGDVSLVDFIRLSQNAIASARNALKNNCEIFVDVPPVCAALDHTRTAHLSTKVNILIDDPHIHSVDEAENKFWQHQELHEGLKQLTPGCVLIIGYAPSVLISALKLIEQQQIQPSLIIGMPIGFSHASAAKRRLMASGVDYITTLGTIGGGLLAAVALNSLMESLIKKPDCHCYLGKGNYNS
>NC_019678.1|WP_044290992.1|4234649_4236599_-|heavy-metal-translocating-P-type-ATPase
MTSSFLRKTDFRQLISEHPDALAAIICAVLLFFGWLCLQFSWVGLALLILCAAYVIGGYESAKEGLTTLFAEKEFDVDLLMIVAALGAAFLGLWRREYYLIVDGAVLILIFAISGALEGYAMQRTNHAISKLMGLTPDTARLILHGEEKQVAIDKLVIDDEILVKPGELIPTDALILKGASNLNEASITGESLPVEKTVGDEVFAGTINGTGALILRVHQPPESSLIQRVIRLVQQAQTEAPPSQIFVENLERNYAKVIVVCGILLAVLPPFIFNWDWETTIYKALIFLVVASPCALMAAIMPALLSAIANGARGGILFKGGAVLELVGKVKAIAFDKTGTLTTGEPQVIEIIAVNGKDANQILSIAAALEVYSEHPIGKAIVLAARDKNLALLSANDIVSHTGFGISGEIEEKYIKVGNAKFIQSEISQLPVDLVAASKNLETHGKTIVWVANNKKILGIIAVADTIRAEAAKTIQRLKRLGIQNIIIVSGDRQLTTNYIAQQLGISEVYAELLPEDKVSVIRRLKRQYQTVAMVGDGINDAPALTTASVGIAMGTTGSDIALETADIVLMADRLEKLVAAIHLGRRSVKVIKQNIIFALCSIGLLLIANFATGINLPLGVIGHEGSTVLVTLSGLRLLKGGNREYNS
>NC_019678.1|WP_044291936.1|4232511_4234041_+|glycerol-kinase-GlpK
MQSRGNTNQQASYILALDLGTTGNRAFVFDANAQIVGQAYLELKQYYPQPGWLEHDATEIWSATISVIQSAVKQAEISPSQIAAIGLTVQRETCLLWDKNTGKPLRKAIVWQDRRTAPLCNELQNQGLAEEIYQRTGLVIDAYFSATKLSWLLDSVAGIDLDNVLAGTIDTWVLWNLTGRKVHATDHSNASRTMLMNLETCDWDETLLNLFKIPRHILPQIQPSLSQFGLTDKDLLGTEIPITAILGDQQASLFGHGCNAPGLMKCTYGTGSFLVAHTGSEIVRSQSQLLSTVAWTQVNQSGSLEISYALEGSMFTSGACIQWLRDGLQLIETAAQTETIATQVDDNGGVYFVPALSGLGAPHWDMSARGSFLGITAGVTREHMVRSVLEAITYQVKEVVEAINASSKTSINKLAVDGGGSNNNFLMQFQADLLGIPIEQPVMRDTTVQGIAFAAGLSIGLWNDYSQLIEQRTIETVFEPNLNSNNIQDIQDNYATWLRAVERGKNWEQ
>NC_019678.1|WP_015119425.1|4230833_4232273_+|DUF4114-domain-containing-protein
MVDNKKIVKGFVAGAALTGAFIAPATAQAADNIGTPSDMMDGIQNAEATQARQEARKERDTARNQAKTFHDLNKKKNVYNVKNNNYQKQLTKYDNGEIDEAKLKNAENQLTNAKKSYEDKLNNLFVDKSEDKELKDTRSSYNKALREYGNAKKKLKEIDDALNKAETIDAEAEKKYEEAKAKYEEAKTKYEPVKKEYNNKLDAAKNGVTDNDLYKSLMVEGNQKIDAQKEAEKSYEAVVAQEWGGWTREHSLTKKDDSQKDLINKFKAELDRIDLKERRAIAKDDVVAQQLDPTKLFLQNDHDVTVWFLDEGAGYRNELAYETSGNTNDKGIIFDDVSKGNGNNRLQMGDFVELGSFEAGTQFNFLLRADGADGTKTSNGDIYGADASLNADSLEHMMAWEIFVDGREYMLMGFEDLRKGGDKDYNDTIFVVDFGKGNLTNKFSKAATVPEASNMAAILGVTGAGLMLRRRRRKKKSVM
>NC_019678.1|WP_015119424.1|4229756_4230140_-|DUF559-domain-containing-protein
MSKSFPRIRGTTPEIEEAAIELRRELTHTEKLLWQALRPRKIGGFKFRRQHPLGRFILDFYCAKCRLVIEVDGEIHHNRQDYDTERTKYLQSYGYTILRFQNHEVIQNLDEVLENILQTALRLCESN
>NC_019678.1|WP_015119435.1|4247550_4248093_-|hypothetical-protein
MDAQNIFQALTSADALRSLIFTLISMGIGAFITYKFLFFIYRKEMKLFRNFKRKLIVLAPENKYGQNMNMEDEVEIIKTNPLFNSLSVKRSSSLRYSNNIDKNCFIILGIGNDFTYFKEAFDKAKNNNITLIIYTYGDNRALEPIHWNLLNSYQWYSVCVTPLRLISEIFNILSTFDFKD
>NC_019678.1|WP_015119436.1|4248473_4250864_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MKNPHQRIITAITWCLAWGEQREPKKMLSEEMLQALRNGETVTDEVAEIVEGVKQLQGITEADFPQTTNELLSKYGDLWKQNTKIGLVYGGATKIKQYVFEAAKLPYIRGASAILDRINLVDLPAFFGAEKDKDFLQLKDEETKRYCQQVREEWLNREDNFPGLFQALIPELIIYSTGGSILAFCPAAFVDDLANAIEKRYTHETLTANSCAVGDTFKLLEFRFGLLSDSIHETFWLDKYLKNQDNAVVKAYFDQPGVDSPQQKFRDRKSFNELVLKLANQFSQRRNGNGNRNNISGNRSSRCYPPMFETHPYLHRDDSDSHNAIVRVENDENQNKGLPNEPWLSETLARKLLMGQITKREYNKGDLPKWWNKLGLNWEPGKIEGWVKRFEDYRFDVPSKYYQGIENPERVEEARSLREIASASTPSGFVAYIYADGNNMGGYIRQKIKSPEDYQRFSQDIFEATEKSVYAAIDKHLRPHYFIPDAKSSRDNKSPVWIHPFEIITIGGDDVLLVVPADKGLEIAKTIGEEFENRLIDENKSQGDYSLVPTKPIDNSKAHRYHSKDSSEQPPVSKCKLSMSTGVLITACDTPIYYADKLVSQLLKSAKKTAKDLKKNHQYYSGTVDFLVMKAVTMISSNIKEFREQGLTKVSPDKPKLKLYSSPYTLYELGGLLKTVGAFKNTNFPRSQLYQIRSLLERGKRTAILNYRYFRVRLQDDNAKQLLEEQFEQTWCEAKTNNGNIAPWMSVGDENEDKNADTTTIYETIWRDIVDLYPFIPEENNTDNSRDNQEFQREVG
>NC_019678.1|WP_015119437.1|4250863_4251580_+|RAMP-superfamily-protein
MVYLDNLSSKATKTISLTAVIDTALCVGAGGSTGSLADKPIVRNAQGQLLIPGSQLKGRLRHECEKLARGLGWKIFLAPLPKTLSPQESEVEDKFKDKYTVPGYRGYHCLVSQIFGDPILPSRILVDDLICSIPATDLAEILRPSVTINRRRRTSDEKKLFFLETSPVNAQLKFEGEIYLLPQSPEYSEALIMAALQHINALGGSKSAGLGWLTWEVSVKTSNKSKNNFDWSQLLPEK
>NC_019678.1|WP_015119438.1|4251576_4252833_+|CRISPR-associated-RAMP-protein-Csx10
MKHLELKITALSPLAIGGQKPGTSVSEVEKYIPGTVIRGAIASQILQLSGGDTGGHFEGLFLGENPAIFHNGYPAIAKVSKDKSEIKNQFAKVVPATGISSKTNPGFKSSGNGVFDTLIDWFCADARNLPYDPSDPNATKSGENPQVEAYRGFYSFDNKNYYSHDVSSRFLTRVGINRRRATSEEEILYSIEVLNESFRKDIETSEWDNFVYCSLITVENNSLADALTRFLNKSSQNFRVGGSASRGLGKVKFAARESKLADKKVKTRITEFNQALENRWNLWSQGFFESKSNLLKRTYFTLNLHSDAILTENWQRTTVVSEEMLKQFTGVDSSLKLHVAYSSYDYGSGWNSAWGLMKDVELLTNKGAVYLFSTEHPEKWYKALEKLEINGIGERTCEGFGRVEICNEFHQVFWENAV
>NC_019678.1|WP_015119439.1|4252829_4253300_+|hypothetical-protein
MNEDNQTRIALKIEGKIRQAEDDLVKAIVDALRDSEYLKSGDKKLEESQFNNLLRVADTSESPEVIKNFIFYQVGRDEKWGRGKKSLAAKIVNDIDGNLQNKASEIAKEAFTGEVPKEEIKKIQMQLIRLYLGYGSRYLKYLNTVNDPKNKSTAII
>NC_019678.1|WP_015119440.1|4253347_4254211_+|CRISPR-associated-RAMP-protein
MFDKFKNRLELTGILTTVTALRISAGRSSEPIGSDLPVVKDALNQPLIPGASFKGAMRSRLESFLRGINQNWAEDPAEFTSKARNETIKGLKEKYKEDDKALTNAILNQTDLVSRLFGSPWIASKFQVRDLTVVKDTWFNQYQERDGVAIERDTETAGSGKLYDFQVVPAGTEFDFKAVVENSESWERGLLMIGLHQFESEQITLGGGSSRGLGVVSLELNKMQWFDSEGDAKKLLEYMENQVNQTMGDYQYSTQEDIDILKREWSEHLINHLYTELDKAVVKQPSN
>NC_019678.1|WP_015119441.1|4254328_4255306_+|RAMP-superfamily-protein
MHKRFVNHCTIELSLIPQGAILIKSGQEDINPSKPKMEFVQTFHSGGSSIYLPGSSLKGAIRSHAERIVRTVGSDKRPTDSDSNQLWANDPLNDKYEYLKDQNNKDLPATEIYKKSSFTDQIFGNTSIASRIRIEDAYPQDKTKLKIEQRHGVAIDRVFGSVAVGPFDYEVCTSGEFHTKIHLKNFSLAQLGLVGLVLRDLNEGWFAIGFAKSRGLGNVKINYHKAVVQYPGCKLEDNQIKAFGKQQTWSNTALLGAGEFLQGENENPYNFPFPDIQNTSIEAEKMELNFGTQLIWNNEGEKTVSNLFELAVNEWSKLLTEGAAA
>NC_019678.1|WP_015119442.1|4255302_4255797_+|hypothetical-protein
MSFVGFKKVSSADELKELLNIYSQQSQQQSYYFLRWLDRVSGIITNLPEDFSNSEGQFFNAELELRWKPEGKGYSILLLRANNHHQDSELGFKEIGGEWEVSEEQNAYFYGVDEKKLPTRFPKGFIYKNQQQENIKPKDIPLAQRNFFNKHTATVHFVALTLKN
>NC_019678.1|WP_015119443.1|4255821_4256889_+|RAMP-superfamily-protein
MTFNRNNPKNNYSSNKDEMGPKPYELIPFPNKPITPKSPPKQGHSQYLPNHLHGTLYLTLLARTSLHVSTGSVVMGSDIDEKPPLIKTMVRTPDNKLIIQGSSIKGCIRSIYEAITNSRLGVISKKYEQSYPEERLPKKNSQNQLCPASLVFGASGEGWGWQSLIDFQDAICEETKYTVGFIPNLWSAQPKKRKAYFNNGETAGRKFYYHMTREIDKGKRDGIPIQQIKQAYFKTQIQFHNLQPQELGTLLVILGQDSEYPLGLKLGGGKPIGMGTITIDITKANISQNLNDLRQRYSSYSTSSQTLTGDKLSNFIQENIKIARKNLIENTQLQAIYEILGYGKKEITRQPYELY
>NC_019678.1|WP_015119444.1|4256888_4257566_+|hypothetical-protein
MVQNTDTLSEESILKEATYLAKALVKEQNYIEPGKDGIRNELDKIVDYLRYTINQNSSETINQNDSKTTSKFFEYLEKSEKDGKTLKRSDVTIDYYSSINKICKKELNNKNYKPEKIIEILAWTSRLIRYYKLEPEQQLLESEPSAQTNSEPSKESRIWEIGEEVEAEITLIKGKEITYKITDDIKRKIKEPKHYQSLKVEQKVIVQITEIRDNLPKKVKFVRSL

Crispr_ID: NC_019678_17

• CRISPR_ID: NC_019678_17
• CRISPR_location: 4257746-4257927
• CRISPR_type: TypeIII
• Repeat_type: A:N
• Spacer_info: 2 spacers
• Cas_protein_info: csx21,csm3gr7,csx19,csm2gr11,csx10gr5,cas10,cas6

Consensus repeat of NC_019678_17

Consensus_repeat	Method
CGTTTCCATCCCCTCTCGGGGTTAAAGAATCAAAACCC	CRISPRCasFinder

spacers of NC_019678_17

>17.1|4257784|33|NC_019678|CRISPRCasFinder
ATTTCCAAAGGGTTAGCAGTAACGAATGGCTAG
>17.2|4257855|35|NC_019678|CRISPRCasFinder
AACGAGTGGGTAAAAGCTACTGGTTAATCGGCGTT

CRISPR arrays and Neighbor proteins around NC_019678_17

CRISPR arrays

The CRISPR arrays of NC_019678_17

>merge|NC_019678|17|4257746-4257927|CRISPRCasFinder
GCTTTTCATCCCCTTTCGGGGTTAAAGAATAAAAACGAATTTCCAAAGGGTTAGCAGTAACGAATGGCTAGCGTTTCCATCCCCTCTCGGGGTTAAAGAATCAAAACCCAACGAGTGGGTAAAAGCTACTGGTTAATCGGCGTTCGTTTCCATCCCCTCTCGGGGTTAAAGAATCAAAACCC

>NC_019678|17|16|4257746-4257927|CRISPRCasFinder
GCTTTTCATCCCCTTTCGGGGTTAAAGAATAAAAACGA	ATTTCCAAAGGGTTAGCAGTAACGAATGGCTAG
CGTTTCCATCCCCTCTCGGGGTTAAAGAATCAAAACCC	AACGAGTGGGTAAAAGCTACTGGTTAATCGGCGTT
CGTTTCCATCCCCTCTCGGGGTTAAAGAATCAAAACCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_044291940.1|4268688_4269894_+|FtsW/RodA/SpoVE-family-cell-cycle-protein	unknown	unknown	gnl|CDD|274232
NC_019678.1|WP_015119441.1|4254328_4255306_+|RAMP-superfamily-protein	csm3gr7	COG1337_csm3gr7_CAS-III-D	gnl|CDD|224256
NC_019678.1|WP_015119435.1|4247550_4248093_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119436.1|4248473_4250864_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cls000742_cas10_CAS-III	gnl|CDD|274208
NC_019678.1|WP_015119442.1|4255302_4255797_+|hypothetical-protein	csx19	cls000059_csx19_CAS-III-D	unknown
NC_019678.1|WP_015119455.1|4270446_4271319_+|DMT-family-transporter	unknown	unknown	gnl|CDD|225308
NC_019678.1|WP_015119437.1|4250863_4251580_+|RAMP-superfamily-protein	csm3gr7	COG1337_csm3gr7_CAS-III-D	gnl|CDD|224256
NC_019678.1|WP_015119451.1|4264946_4265690_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_019678.1|WP_015119444.1|4256888_4257566_+|hypothetical-protein	csx21	mkCas0116_csx21_CAS-III-A:CAS-III-D	unknown
NC_019678.1|WP_015119438.1|4251576_4252833_+|CRISPR-associated-RAMP-protein-Csx10	csx10gr5	cd09700_csx10gr5_CAS-III-D	gnl|CDD|131722
NC_019678.1|WP_015119443.1|4255821_4256889_+|RAMP-superfamily-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NC_019678.1|WP_044290997.1|4264194_4264758_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_019678.1|WP_015119439.1|4252829_4253300_+|hypothetical-protein	csm2gr11	mkCas0063_csm2gr11_CAS-III-D	unknown
NC_019678.1|WP_015119447.1|4259833_4260946_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl|CDD|227838
NC_019678.1|WP_015119445.1|4258252_4258999_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_044290996.1|4262957_4263833_-|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224016
NC_019678.1|WP_015119440.1|4253347_4254211_+|CRISPR-associated-RAMP-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187814
NC_019678.1|WP_015119453.1|4266505_4267834_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_019678.1|WP_044291939.1|4261029_4262190_-|alpha-D-ribose-1-methylphosphonate-5-triphosphate-diphosphatase	unknown	unknown	gnl|CDD|237967
NC_019678.1|WP_015119446.1|4259024_4259603_+|HD-domain-containing-protein	unknown	unknown	gnl|CDD|379122

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019678.1|WP_015119438.1|4251576_4252833_+|CRISPR-associated-RAMP-protein-Csx10	csx10gr5	cd09700_csx10gr5_CAS-III-D	3.1e-129	426.5	0.0
NC_019678.1|WP_015119443.1|4255821_4256889_+|RAMP-superfamily-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	5.2e-43	142.6	5.3
NC_019678.1|WP_015119441.1|4254328_4255306_+|RAMP-superfamily-protein	csm3gr7	COG1337_csm3gr7_CAS-III-D	1.4e-55	183.2	0.0
NC_019678.1|WP_015119439.1|4252829_4253300_+|hypothetical-protein	csm2gr11	mkCas0063_csm2gr11_CAS-III-D	7.2e-60	195.9	1.7
NC_019678.1|WP_015119447.1|4259833_4260946_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	1.1e-49	164.0	0.1
NC_019678.1|WP_015119436.1|4248473_4250864_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cls000742_cas10_CAS-III	2.3e-82	271.9	0.0
NC_019678.1|WP_015119442.1|4255302_4255797_+|hypothetical-protein	csx19	cls000059_csx19_CAS-III-D	3.9e-48	157.8	2.2
NC_019678.1|WP_015119440.1|4253347_4254211_+|CRISPR-associated-RAMP-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	8.9e-72	235.7	0.0
NC_019678.1|WP_015119437.1|4250863_4251580_+|RAMP-superfamily-protein	csm3gr7	COG1337_csm3gr7_CAS-III-D	9.9e-33	108.3	0.0
NC_019678.1|WP_015119444.1|4256888_4257566_+|hypothetical-protein	csx21	mkCas0116_csx21_CAS-III-A:CAS-III-D	3.4e-67	220.8	12.8

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_044291940.1|4268688_4269894_+|FtsW/RodA/SpoVE-family-cell-cycle-protein	gnl|CDD|274232	TIGR02614, Putative_lipid_II_flippase_FtsW, cell division protein FtsW. This family consists of FtsW, an integral membrane protein with ten transmembrane segments. In general, it is one of two paralogs involved in peptidoglycan biosynthesis, the other being RodA, and is essential for cell division. All members of the seed alignment for this model are encoded in operons for the biosynthesis of UDP-N-acetylmuramoyl-pentapeptide, a precursor of murein (peptidoglycan). The FtsW designation is not used in endospore-forming bacterial (e.g. Bacillus subtilis), where the member of this family is designated SpoVE and three or more RodA/FtsW/SpoVE family paralogs are present. SpoVE acts in spore cortex formation and is dispensible for growth. Biological rolls for FtsW in cell division include recruitment of penicillin-binding protein 3 to the division site. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	2.84952e-95
NC_019678.1|WP_015119441.1|4254328_4255306_+|RAMP-superfamily-protein	gnl|CDD|224256	COG1337, COG1337, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.75828e-40
NC_019678.1|WP_015119455.1|4270446_4271319_+|DMT-family-transporter	gnl|CDD|225308	COG2510, COG2510, Predicted membrane protein [Function unknown].	3.41861e-07
NC_019678.1|WP_015119436.1|4248473_4250864_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl|CDD|274208	TIGR02577, thermophile-specific_DNA_repair_system, CRISPR-associated protein Cas10/Cmr2, subtype III-B. This model represent a Crm2 family of the CRISPR-associated RAMP module, a set of six genes recurring found together in prokaryotic genomes. This gene cluster is found only in species with CRISPR repeats, usually near the repeats themselves. Because most of the six (but not this family) contain RAMP domains, and because its appearance in a genome appears to depend on other CRISPR-associated Cas genes, the set is designated the CRISPR RAMP module. This protein, typified by TM1794 from Thermotoga maritima, is designated Crm2, for CRISPR RAMP Module protein 2.	3.64674e-44
NC_019678.1|WP_044290997.1|4264194_4264758_-|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	7.10822e-26
NC_019678.1|WP_015119437.1|4250863_4251580_+|RAMP-superfamily-protein	gnl|CDD|224256	COG1337, COG1337, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	4.39345e-37
NC_019678.1|WP_015119451.1|4264946_4265690_-|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.18637e-19
NC_019678.1|WP_015119438.1|4251576_4252833_+|CRISPR-associated-RAMP-protein-Csx10	gnl|CDD|131722	TIGR02674, cas_cyan_RAMP_2, CRISPR-associated RAMP protein, Csx10 family. CRISPR is a widespread repeat family in prokaryotes. At least 45 different protein families occur in prokaryotes only when these repeats are present. This family, a minor CRISPR-associated protein family, seems largely restricted to the Cyanobacteria. It belongs to the RAMP superfamily (pfam03787).	1.06826e-133
NC_019678.1|WP_015119443.1|4255821_4256889_+|RAMP-superfamily-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	2.40975e-17
NC_019678.1|WP_015119447.1|4259833_4260946_+|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	4.2461e-37
NC_019678.1|WP_044290996.1|4262957_4263833_-|NAD(P)-dependent-oxidoreductase	gnl|CDD|224016	COG1091, RfbD, dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane].	1.79267e-81
NC_019678.1|WP_015119440.1|4253347_4254211_+|CRISPR-associated-RAMP-protein	gnl|CDD|187814	cd09683, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	5.37131e-76
NC_019678.1|WP_015119453.1|4266505_4267834_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	7.10208e-24
NC_019678.1|WP_044291939.1|4261029_4262190_-|alpha-D-ribose-1-methylphosphonate-5-triphosphate-diphosphatase	gnl|CDD|237967	PRK15446, PRK15446, phosphonate metabolism protein PhnM; Provisional.	1.9883e-132
NC_019678.1|WP_015119446.1|4259024_4259603_+|HD-domain-containing-protein	gnl|CDD|379122	pfam13328, HD_4, HD domain. HD domains are metal dependent phosphohydrolases.	2.62511e-31

Protein sequences

>NC_019678.1|WP_015119444.1|4256888_4257566_+|hypothetical-protein
MVQNTDTLSEESILKEATYLAKALVKEQNYIEPGKDGIRNELDKIVDYLRYTINQNSSETINQNDSKTTSKFFEYLEKSEKDGKTLKRSDVTIDYYSSINKICKKELNNKNYKPEKIIEILAWTSRLIRYYKLEPEQQLLESEPSAQTNSEPSKESRIWEIGEEVEAEITLIKGKEITYKITDDIKRKIKEPKHYQSLKVEQKVIVQITEIRDNLPKKVKFVRSL
>NC_019678.1|WP_015119443.1|4255821_4256889_+|RAMP-superfamily-protein
MTFNRNNPKNNYSSNKDEMGPKPYELIPFPNKPITPKSPPKQGHSQYLPNHLHGTLYLTLLARTSLHVSTGSVVMGSDIDEKPPLIKTMVRTPDNKLIIQGSSIKGCIRSIYEAITNSRLGVISKKYEQSYPEERLPKKNSQNQLCPASLVFGASGEGWGWQSLIDFQDAICEETKYTVGFIPNLWSAQPKKRKAYFNNGETAGRKFYYHMTREIDKGKRDGIPIQQIKQAYFKTQIQFHNLQPQELGTLLVILGQDSEYPLGLKLGGGKPIGMGTITIDITKANISQNLNDLRQRYSSYSTSSQTLTGDKLSNFIQENIKIARKNLIENTQLQAIYEILGYGKKEITRQPYELY
>NC_019678.1|WP_015119442.1|4255302_4255797_+|hypothetical-protein
MSFVGFKKVSSADELKELLNIYSQQSQQQSYYFLRWLDRVSGIITNLPEDFSNSEGQFFNAELELRWKPEGKGYSILLLRANNHHQDSELGFKEIGGEWEVSEEQNAYFYGVDEKKLPTRFPKGFIYKNQQQENIKPKDIPLAQRNFFNKHTATVHFVALTLKN
>NC_019678.1|WP_015119441.1|4254328_4255306_+|RAMP-superfamily-protein
MHKRFVNHCTIELSLIPQGAILIKSGQEDINPSKPKMEFVQTFHSGGSSIYLPGSSLKGAIRSHAERIVRTVGSDKRPTDSDSNQLWANDPLNDKYEYLKDQNNKDLPATEIYKKSSFTDQIFGNTSIASRIRIEDAYPQDKTKLKIEQRHGVAIDRVFGSVAVGPFDYEVCTSGEFHTKIHLKNFSLAQLGLVGLVLRDLNEGWFAIGFAKSRGLGNVKINYHKAVVQYPGCKLEDNQIKAFGKQQTWSNTALLGAGEFLQGENENPYNFPFPDIQNTSIEAEKMELNFGTQLIWNNEGEKTVSNLFELAVNEWSKLLTEGAAA
>NC_019678.1|WP_015119440.1|4253347_4254211_+|CRISPR-associated-RAMP-protein
MFDKFKNRLELTGILTTVTALRISAGRSSEPIGSDLPVVKDALNQPLIPGASFKGAMRSRLESFLRGINQNWAEDPAEFTSKARNETIKGLKEKYKEDDKALTNAILNQTDLVSRLFGSPWIASKFQVRDLTVVKDTWFNQYQERDGVAIERDTETAGSGKLYDFQVVPAGTEFDFKAVVENSESWERGLLMIGLHQFESEQITLGGGSSRGLGVVSLELNKMQWFDSEGDAKKLLEYMENQVNQTMGDYQYSTQEDIDILKREWSEHLINHLYTELDKAVVKQPSN
>NC_019678.1|WP_015119439.1|4252829_4253300_+|hypothetical-protein
MNEDNQTRIALKIEGKIRQAEDDLVKAIVDALRDSEYLKSGDKKLEESQFNNLLRVADTSESPEVIKNFIFYQVGRDEKWGRGKKSLAAKIVNDIDGNLQNKASEIAKEAFTGEVPKEEIKKIQMQLIRLYLGYGSRYLKYLNTVNDPKNKSTAII
>NC_019678.1|WP_015119438.1|4251576_4252833_+|CRISPR-associated-RAMP-protein-Csx10
MKHLELKITALSPLAIGGQKPGTSVSEVEKYIPGTVIRGAIASQILQLSGGDTGGHFEGLFLGENPAIFHNGYPAIAKVSKDKSEIKNQFAKVVPATGISSKTNPGFKSSGNGVFDTLIDWFCADARNLPYDPSDPNATKSGENPQVEAYRGFYSFDNKNYYSHDVSSRFLTRVGINRRRATSEEEILYSIEVLNESFRKDIETSEWDNFVYCSLITVENNSLADALTRFLNKSSQNFRVGGSASRGLGKVKFAARESKLADKKVKTRITEFNQALENRWNLWSQGFFESKSNLLKRTYFTLNLHSDAILTENWQRTTVVSEEMLKQFTGVDSSLKLHVAYSSYDYGSGWNSAWGLMKDVELLTNKGAVYLFSTEHPEKWYKALEKLEINGIGERTCEGFGRVEICNEFHQVFWENAV
>NC_019678.1|WP_015119437.1|4250863_4251580_+|RAMP-superfamily-protein
MVYLDNLSSKATKTISLTAVIDTALCVGAGGSTGSLADKPIVRNAQGQLLIPGSQLKGRLRHECEKLARGLGWKIFLAPLPKTLSPQESEVEDKFKDKYTVPGYRGYHCLVSQIFGDPILPSRILVDDLICSIPATDLAEILRPSVTINRRRRTSDEKKLFFLETSPVNAQLKFEGEIYLLPQSPEYSEALIMAALQHINALGGSKSAGLGWLTWEVSVKTSNKSKNNFDWSQLLPEK
>NC_019678.1|WP_015119436.1|4248473_4250864_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MKNPHQRIITAITWCLAWGEQREPKKMLSEEMLQALRNGETVTDEVAEIVEGVKQLQGITEADFPQTTNELLSKYGDLWKQNTKIGLVYGGATKIKQYVFEAAKLPYIRGASAILDRINLVDLPAFFGAEKDKDFLQLKDEETKRYCQQVREEWLNREDNFPGLFQALIPELIIYSTGGSILAFCPAAFVDDLANAIEKRYTHETLTANSCAVGDTFKLLEFRFGLLSDSIHETFWLDKYLKNQDNAVVKAYFDQPGVDSPQQKFRDRKSFNELVLKLANQFSQRRNGNGNRNNISGNRSSRCYPPMFETHPYLHRDDSDSHNAIVRVENDENQNKGLPNEPWLSETLARKLLMGQITKREYNKGDLPKWWNKLGLNWEPGKIEGWVKRFEDYRFDVPSKYYQGIENPERVEEARSLREIASASTPSGFVAYIYADGNNMGGYIRQKIKSPEDYQRFSQDIFEATEKSVYAAIDKHLRPHYFIPDAKSSRDNKSPVWIHPFEIITIGGDDVLLVVPADKGLEIAKTIGEEFENRLIDENKSQGDYSLVPTKPIDNSKAHRYHSKDSSEQPPVSKCKLSMSTGVLITACDTPIYYADKLVSQLLKSAKKTAKDLKKNHQYYSGTVDFLVMKAVTMISSNIKEFREQGLTKVSPDKPKLKLYSSPYTLYELGGLLKTVGAFKNTNFPRSQLYQIRSLLERGKRTAILNYRYFRVRLQDDNAKQLLEEQFEQTWCEAKTNNGNIAPWMSVGDENEDKNADTTTIYETIWRDIVDLYPFIPEENNTDNSRDNQEFQREVG
>NC_019678.1|WP_015119435.1|4247550_4248093_-|hypothetical-protein
MDAQNIFQALTSADALRSLIFTLISMGIGAFITYKFLFFIYRKEMKLFRNFKRKLIVLAPENKYGQNMNMEDEVEIIKTNPLFNSLSVKRSSSLRYSNNIDKNCFIILGIGNDFTYFKEAFDKAKNNNITLIIYTYGDNRALEPIHWNLLNSYQWYSVCVTPLRLISEIFNILSTFDFKD
>NC_019678.1|WP_015119445.1|4258252_4258999_-|hypothetical-protein
MDLLSIFDYSQLLDVIAQTTTSSPTQTPKETVDTVTLLKTQLDFLKFIIQLAVFVFAVLGAWITFVFGKNLSDAKKVAEEIISQKVEARVDNLIKTEVQSLRKSIDREKAIIFTYVDYYLPSSAMEPKEFKLIKARGFRDVFFWNRHNPPKRLSGNVCVLDLQNYKDDKGQEFSKLSQDDKEKKVETHVNEILPLLKPETVLVIYARGRFNAIENIPNSRYYVPANSVVTLIGWVADSAYVAYGEEMV
>NC_019678.1|WP_015119446.1|4259024_4259603_+|HD-domain-containing-protein
MILKQPAKLTTKFEQALIYATQLHANQTRKVDKIPYISHLMSVSALILEAGGTEDEAIAGLLHDAIEDQGGKATREEIRQKFGETVVEIVDGCTETDITPKPPWKERKIDYIENIRKGSDSVKLVSFADKLHNARSLLIGYRNKGDKLWDYFSGSKEDKLWFYGELLEIYQQSCDNFMTVELERILEELGNH
>NC_019678.1|WP_015119447.1|4259833_4260946_+|CRISPR-associated-endoribonuclease-Cas6
MPIRRTRKKSSAIITLPTDTELVGIVFHISPASNYTIFPEYAKGLHAWFLNQVRQTNPELSTYLHDGESEKPFTISRLQGKFLSNDAKLQLAADSNYQWYVSALSSRLVAWMADWLQNLPKTIELHNAPLQIKSVEIAHPATTYKKLLENKKAKNTLSLSYISPTSFRRKKHHFPLPLPFNIFQSYLRRWNDFSNLPVEQDTFLEWVDENVIIQRHQISTTRVPGGKRGLVTGFTGAVEFGLGKEASKEPEYVNLYRALGKLAPYCGTGHKTTFGLGQTRLGWLIEEEKIEVVSPQELLANRIAQITEILMSKQKRTGGSRAISVCQKRAAIMARRETGESLQDIATDLDIPYETVKTYVKLTRKMLAES
>NC_019678.1|WP_044291939.1|4261029_4262190_-|alpha-D-ribose-1-methylphosphonate-5-triphosphate-diphosphatase
MKTNTKVVIEGVDVLTTEGWEKDTNVLIEDGRFISIKRTANKDGCQRIKAKGLQMFPGIVDLHGDAFERTICPRPGVNIPLAMAMIENDRNLLAAGITTYFCAITDSYEPGLRSRDTARDLINFIWGEGQHLLSCNHLIHIRHELTNIRGHEELCTWLQKRRIHFLSINDHLPPVEDRYKWRRHISNLRRRVILSNQEIIDMLTQLQEYRQEGSLQVEQLVELAHIYNIPVASHDDDSEEKVALSHRRRMAIAEFPANVDLAAQERKYGASVLMGAPNLLQGGSHMGWMSVEEALKNKVLDCLCSDYHYPSLFYAPFKLHSEGLMPLEKAWELVSSRPAAAIGLGKQKGKIAPGFDADFLLIRPENTLPSSIASVYIQGKEVAKYS
>NC_019678.1|WP_044290996.1|4262957_4263833_-|NAD(P)-dependent-oxidoreductase
MKKLLITGSSGFLGWHLCELAKQKWDVYGTYFSHNLDIEGTKLVKLDLTDFSELKKLFQEIQPSAVIHTAAQSQPNFCQTHPEESLSINVTASLNIAGLCADNSIPCVFTSTDLVFDGLKGFYKETDSVNPVNIYGEHKVIAENGMLKRYPQTAICRMPLMFGGATPTATSFLQSFLKTLQEGKELKLFVDEFRTPVSGKTAAEGLLLALDKGIGIIHLGGKERISRYDFGRLLVEIFDIPSAKITASLQKDVKMAAPRASDVSLDSSKAFELGYAPSSLREQLFSVRNYR
>NC_019678.1|WP_044290997.1|4264194_4264758_-|Uma2-family-endonuclease
MYSQPKYIDSSIDEYLQFDLESLVRYEYINGQMYPLVGESYNLKIISENIFSRLRTQLYGTDCHVFASDMKVRIEPINAFYYPEASVVKDSQDRDMYFKSRPCLIVEVISPITERIDRIEKLYNYRQIPSLQEYVLVHQSQMKIEVYRKVYGNQWFLETLAEETILKMQSVEVEMTMAEIYEDVEFE
>NC_019678.1|WP_015119451.1|4264946_4265690_-|tetratricopeptide-repeat-protein
MAFCSRFVASGLTAFLILGCSDWAESTRQDNKKAVQETNVARLLTQASVRQTEDFFVQGNKFLEANRYEDAIAAYDQVVIAAPDNAEAWINRGNALAALQRYGQALGSYDRAIAVQPKRDEAWYNRGNTLSAMRLYQEAVVSYDKAIAIKPDKYEAWINRGIALTNLQRYKQALASYDKAIAIKPDKHQAYYNKACTYALQKNTTAAMDNLQKAMKLFPGKYEKLAKIDPDFAKVRNTKQFQELIQR
>NC_019678.1|WP_015119453.1|4266505_4267834_+|pentapeptide-repeat-containing-protein
MSIESNSHSSQSRSQQPASEDKWQPDEFESIAGTNELPNGLSAQQVNSAIASVQSQQNTTALQQARSTFPENSSTELQVTPRALLITLFTTLVTVVGIVINQPIVGIVGTVSTLLLSAIILFPWLQVVVTELLTPQQRALIIAFLGITVAIAGLVKFVPGTIDWDISGTLADWFGALGQILIAIIAVYVAWRQYVISKDLTIQQNLLTIQQNNITQQQTIDTYFQGISDLVLDEEGLLEDWPQERLLAEGRTASILSSVDAVGKAKILRFLSRSKLLTPLQRDAHLGRAILDGSGGYAEDLVAGVRVIDLGVMLAGANLSGTDLRWTDLSEANLVRVNLNNCDLVKSNLCRAILYEANLSGADLNGTKLFYGSLETASPRSRLHPPNYRTGERTGAVVEKANFTNIKRISQANRHYCCSWCGEESRKTIPGGCEGIENKLGR
>NC_019678.1|WP_044291940.1|4268688_4269894_+|FtsW/RodA/SpoVE-family-cell-cycle-protein
MRLIRLIPFLDDTVSSWALEARLLRWLSLIWLFVGLAVLFSASYPLADVKHGDGLFLFKRQLITVFLGLILFNIIVNLPFHKIIGVSHWLLMLFLGLIFLTLVPGLGTRGIYGTTRWFSIGGFTIQPSEFIKPFLVLQSARVFGNWERLSWGIRIAWLVVFGFALLGILAQPNLSTTALCGITIWLIALAAGLPYKYLGGSAGAGVILALMSVTVNKYQRLRITSFINPWDDPQGTDYQLIQSLLAVGSGNTWGSGFGLSQQKLSWLPIADSDFIFAVFAEEFGFVGSVTLLVMLAVFATLGFIVALKAKSVIYRLSAVGITTLLTGQSFINIGVASGVLPTTGLPLPFFSYGGSSIIATLVATALLIRVARESNEAEVVPIRRQPTKPRRERRFLHRNKS
>NC_019678.1|WP_015119455.1|4270446_4271319_+|DMT-family-transporter
MSWFFFAISTAFLESLRDIFNKKTVSVIDEYILVFSFNLLTAIFASPLLFFNDIPALGDNFFYALIAIGVFNTIAFVLFFKAIKASDLSIVAPITTLSPIFLLITSPFIVGEFPNAIGILGIFIIVIGAYVLKFQDKTSGYLAPFKSLFKETGSRLMFGVVLVWSITANVDKIGVQNSSPIFWTITAHLSVALFILPIVFLNSKPNIQNIKSNFKNLILIGFINTLAILCQMSALQLALVSFVIAVKRTSALFNVLWGWLIFKEQGIKERIAGSMIMILGVVVITLSKMF

Crispr_ID: NC_019678_18

• CRISPR_ID: NC_019678_18
• CRISPR_location: 4282768-4282929
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 2 spacers

Consensus repeat of NC_019678_18

Consensus_repeat	Method
TGTTTCTGGATAATGGAAAGTCGAATCGCTACTTTGTTCGCTGTAATTTGGAGT	PILER-CR

spacers of NC_019678_18

>18.1|4282822|28|NC_019678|PILER-CR
CCACCTAATTGTTTTTTGGGAGTTACTA
>18.2|4282904|3|NC_019678|PILER-CR
AGT

CRISPR arrays and Neighbor proteins around NC_019678_18

CRISPR arrays

The CRISPR arrays of NC_019678_18

>merge|NC_019678|18|4282768-4282929|PILER-CR
TGGTTCTGGATAATGGAAAGTTGAACCACCTAATTGTTTTTTGGGAGTTACTATTTCTGGATAATGGAAAGTCGAATCGCTACTTTGTTCGCTGTAATTTGGAGTAGTTGTTTCTGGATAATGGAAAGTCGAATCGCTACTTTGTTCGCTGTAATTTGGAGT

>NC_019678|18|5|4282768-4282929|PILER-CR
TGGTTCTGGATAATGGAAAGTTGAACCACCTAATTGTTTTTTGGGAGTTACTAT	TTCTGGATAATGGAAAGTCGAATCGCTA
CTTTGTTCGCTGTAATTTGGAGTAGTTGTTTCTGGATAATGGAAAGTCGAATCG	CTA
CTTTGTTCGCTGTAATTTGGAGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_044290999.1|4289550_4292613_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|225183
NC_019678.1|WP_015119476.1|4295509_4295812_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119478.1|4296504_4296708_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119459.1|4275015_4275402_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl|CDD|237320
NC_019678.1|WP_015119457.1|4272397_4273798_+|cytochrome-c-biogenesis-protein	unknown	unknown	gnl|CDD|214387
NC_019678.1|WP_015119464.1|4278759_4279302_+|2'-5'-RNA-ligase	unknown	unknown	gnl|CDD|224431
NC_019678.1|WP_015119477.1|4296035_4296332_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119465.1|4279465_4279759_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119462.1|4276738_4277005_-|hypothetical-protein	unknown	unknown	gnl|CDD|367663
NC_019678.1|WP_015119471.1|4287256_4287451_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119470.1|4285550_4286426_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119475.1|4294380_4295163_+|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|223831
NC_019678.1|WP_015119472.1|4288997_4289462_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119463.1|4277260_4278220_-|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	gnl|CDD|131644
NC_019678.1|WP_015119469.1|4285087_4285237_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119466.1|4280280_4281345_+|peptidoglycan-binding-protein	unknown	unknown	gnl|CDD|225943
NC_019678.1|WP_015119474.1|4292768_4294319_+|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|130902
NC_019678.1|WP_015119460.1|4275523_4275922_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119461.1|4276175_4276559_-|phasin-family-protein	unknown	unknown	gnl|CDD|226447
NC_019678.1|WP_044290998.1|4273867_4274518_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_044290999.1|4289550_4292613_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|225183	COG2274, SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms].	0
NC_019678.1|WP_015119463.1|4277260_4278220_-|PEP-CTERM-sorting-domain-containing-protein	gnl|CDD|131644	TIGR02595, conserved_hypothetical_protein, PEP-CTERM protein-sorting domain. This model describes a 25-residue domain that includes a near-invariant Pro-Glu-Pro (PEP) motif, a thirteen residue strongly hydrophobic sequence likely to span the membrane, and a five-residue strongly basic motif that often contains four Arg residues. In nearly every case, this motif is found within nine residues, and usually within five residues, of the extreme C-terminus of the protein. Proteins with this motif typically have signal sequences at the N-terminus. This region appears many times per genome or not at all, and co-occurs in genomes with a proposed protein-sorting integral membrane protein we designate exosortase (see TIGR02602). PEP-CTERM proteins frequently are poorly conserved, Ser/Thr-rich proteins and may become extensively modified proteinaceous constituents of extracellular material in bacterial biofilms. [Cell envelope, Surface structures].	2.76349e-05
NC_019678.1|WP_015119459.1|4275015_4275402_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl|CDD|237320	PRK13258, PRK13258, 7-cyano-7-deazaguanine reductase; Provisional.	3.83425e-68
NC_019678.1|WP_015119466.1|4280280_4281345_+|peptidoglycan-binding-protein	gnl|CDD|225943	COG3409, COG3409, Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane].	1.05842e-18
NC_019678.1|WP_015119457.1|4272397_4273798_+|cytochrome-c-biogenesis-protein	gnl|CDD|214387	CHL00177, ccs1, c-type cytochrome biogenensis protein; Validated.	2.31158e-175
NC_019678.1|WP_015119464.1|4278759_4279302_+|2'-5'-RNA-ligase	gnl|CDD|224431	COG1514, LigT, 2'-5' RNA ligase [Translation, ribosomal structure and biogenesis].	2.22413e-28
NC_019678.1|WP_015119461.1|4276175_4276559_-|phasin-family-protein	gnl|CDD|226447	COG3937, COG3937, Uncharacterized conserved protein [Function unknown].	3.92585e-16
NC_019678.1|WP_015119462.1|4276738_4277005_-|hypothetical-protein	gnl|CDD|367663	pfam03795, YCII, YCII-related domain. The majority of proteins in this family consist of a single copy of this domain, though it is also found as a repeat. A strongly conserved histidine and a aspartate suggest that the domain has an enzymatic function. This family also now includes the family formerly known as the DGPF domain (COG3795). Although its function is unknown it is found fused to a sigma-70 factor family domain in CC_1329. Suggesting that this domain plays a role in transcription initiation (Bateman A per. obs.). This domain is named after the most conserved motif in the alignment.	2.39486e-07
NC_019678.1|WP_015119474.1|4292768_4294319_+|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	gnl|CDD|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	1.02747e-59
NC_019678.1|WP_015119475.1|4294380_4295163_+|peptidylprolyl-isomerase	gnl|CDD|223831	COG0760, SurA, Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones].	1.25363e-09

Protein sequences

>NC_019678.1|WP_015119466.1|4280280_4281345_+|peptidoglycan-binding-protein
MTTSLIVLEAGAAGLKVTKLQEALKQLNFYFSSIDGIFGTKTKAAVVKFQQPYSHLPNNGLVDAETILQLDEDVWLSAKEVLREGCTGEDVKALQEIFTVFDLHTLIVDGYFGRKTKEAVIWFQQNWGLQADGIVGKQTWAGLYRHQVHDIPYEDRVKAFFGELDTESFIKLPLQKGDKGNDVLILQKFFNHASGSTHGILEDGDFGQATEQAVQTFQQRNGLTSDGCVGMQTYQAMLWEGLNQQLINELLSIRKSKSIDFSNGNEYEVIEDAAIRGETVIHRFEVAPGQDFRIVITSVENNAIFELFKVGEPRMYAEKASNIRLFLEAGEYYFTVGAIRGNATYKLKVESVSC
>NC_019678.1|WP_015119465.1|4279465_4279759_+|hypothetical-protein
MQPETKQAYQEKVKAQLDKLNAQIDQIKAQAAEAKADAEIDYRGTIENLTSKRNAAQAKLDEISKASEDAWEDLKVGFESAWNELDAAFKNAMNKFQ
>NC_019678.1|WP_015119464.1|4278759_4279302_+|2'-5'-RNA-ligase
MSLYFIALLPPQTIQDYATGVKQYFADNYDSKHAFKSPPHITLQPPFEWDTDKAVALEECLQNFVMGRNVIPITLDGYNAFPPRVIYIDVVQTPDLMNLQGDLMAYLENNLGIVDKVGKSRGFTPHMTVAFKDLKRSKFYAAWEEFKNRELHFEFDARKLTLLKHENKRWNIVKEFEFVF
>NC_019678.1|WP_015119463.1|4277260_4278220_-|PEP-CTERM-sorting-domain-containing-protein
MKFKELGLVFASLAVSLVGIASSASSAKAASFFGEDLQHFGNPSSSDRVTDVPFASELENSFQAEQDFLNALGGASIGTVNFEVNEGFTADGDNDEDKNQGRLYYDLDVKTTDGSIVNMEILDENLNAQTPGVDDWKLRSSIEKTNGKANGGTNFQGGRYGISEEGTDWQENQFLNTNAGKDSSIVFDFAQKMSAFGFYGTDFERGGVMGVEFTLASGDTKYVSLGISDPETMKKEKNVDTIRGTAFYSGYIADSEADYFTQVRFDVSDTVKGTNDMVAFDRMTFAKAEVPEPTTGILALGAVVSGAVFRRRKKKFTIT
>NC_019678.1|WP_015119462.1|4276738_4277005_-|hypothetical-protein
MPWFAKIETGKVDKSTFDKYVPAHKAYVEDLKNKGHEAKTGYWAQYGGGMLLFKAASMDEAQAIVSRDPLIENNCVDYKLYEWRLIVE
>NC_019678.1|WP_015119461.1|4276175_4276559_-|phasin-family-protein
MPGFGDIAKKAFYLGVGLASYASEKAGGTLAELRSQAQKLADEMVAKGEMNAEEARKFVEDMMKQAQSSASDGSEESTTRAEPRRIEILGDDEEPSEKESPEVQDVDKLRDQVKRMQEELRRLQRDQ
>NC_019678.1|WP_015119460.1|4275523_4275922_-|hypothetical-protein
MDEWQKDFSDIVKSVSDEVERFFTGMTEVVDTFIEMTEELSEQVQTSLLSEVDQYLQDLAEPFLEVYWDFEDVLGDDLSSHLPYPVEPTAEKNPACMGCRNYHGQVYNGNLLVCGMHPSGYEDESCPDWEGE
>NC_019678.1|WP_015119459.1|4275015_4275402_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MTQTDIEVKYGEREISEGKLITFPNPRVGRRYNISITLPEFTCKCPFSGYPDFATIYVNYVPDEKVVELKAIKLYINSYRDRYISHEESANQILDDIVAACDPLEINVKADFTPRGNVHTVVEVNHKK
>NC_019678.1|WP_044290998.1|4273867_4274518_+|hypothetical-protein
MQDLNIGFLSANQTTVKSKGREFLDLLRTYLPAFNPVRYGAWEPLNNYFNFSNIEKPLQCSNNEYFLWKSKRHACEEIASMDSKSIHSSIDIIGKSESVDCTQVVSFFLKTTELIKPDFAYVHLFSDEELHTITKGINTTFYDMSMPFRTGISTYELRKYIPNLCWGTIFGSPYIKLFEREHILSSPASKVQQLSENAIYIQLSEDLTDLKQLIKA
>NC_019678.1|WP_015119457.1|4272397_4273798_+|cytochrome-c-biogenesis-protein
MTLEESSKSPLAAFTSFIRKEFLPVLTDLRLAIILLLAIAAFSITGTVIEQGQSVAFYQENYPENPALFGFITWKVVIILGLDHVYRTWWFLSLLIFFGASLTACTFTRQLPALKAARRWKFFDKPRRFQKLALSAEFDVDKDNFTSIQNLTEILQQRRYKVFQEDNDKLYARKGIIGKIGPIIVHIGIVVILLGSILGAMTGFMAQEMVASGDTFQVKNIIDAGPWAMSQVPKDWAVKVNRFWIDYTSTGEIDQFYSDMSVLDQEGKEVDKDTIFVNHPLRHKGVTLYQTDWGIAAVKVKVNRSPIFELPMAQLDTGGKGRLWGTWIPTKPDLSEGVSLLAKDLQGTVLIYDAKGKLVNTVREGMTAEVNGVTLKILEVVGSTGLQIKADPGIPVVYAGFALLMMGVVMSYFSHSQVWVLQEEDNLYVGGKTNRAQVAFEGEMVEIFEQVNSQSKGESTKSLVSI
>NC_019678.1|WP_015119469.1|4285087_4285237_-|hypothetical-protein
MRQVQAMTCPKFTNDFFGDRQLEIIAFCELTRSQSQVRHFKGLAHLNPP
>NC_019678.1|WP_015119470.1|4285550_4286426_+|hypothetical-protein
MGKSIVELVDNLPADNITVKVLKALDFIVPGEWENLVGFDNAISQITGETKSKKIKKIRKKAEKLYDEKENGYQTAIWIYQTLDTTDKAVGAAALANKIGNSFSFIPFLKELTPRADTLQSIDLKMKLVAELIAYSKLNGLTLSPQKFAASLKENYQNEALMRMVALVCIDGVLPLGTNFVPKIENDITQRENLENNPAFSAVSKFIPSSDKTGFINDSFKAVDEWMAKLTDSAGLSRESIASHLSNFIDIADDKLDYLAAFLDTSTNYFEHTGIQTVARKVIKEAYQEID
>NC_019678.1|WP_015119471.1|4287256_4287451_+|hypothetical-protein
MVQEVSLKKLWRLLKVSQYAKQKVIEHLPNVFIIFFAGFFLTLKTALSLIAMQNFALNSNDAIC
>NC_019678.1|WP_015119472.1|4288997_4289462_+|hypothetical-protein
MSYQFSFLQAFAGYDFAKSRFFAALNQNTLLKSLQICLRVDFYRQIKIMLFTDSSKHSTHICYKLEFFSQMYLDGAVIEYGTLLERWLYLIENRFKALQNQYSWHFRKHIRESSSDCNRSYIFDNNIAKVLCKYLLRIRLSQEKKNYLLGRKLY
>NC_019678.1|WP_044290999.1|4289550_4292613_+|ATP-binding-cassette-domain-containing-protein
MQNVCSQGELREKIFAILGESLEEQDLEGCLKSLKVVEPEATKLFWQATEAQPGIYVVLEGRVRILDNSDNLIATVSSDAAFGEQSLFNQQNFLFLAAKASTSVKLCFIPGAILSELIEKKLQIRDNLYKRAEFWDLLLLCRQNSQLPSNISLKNIFKALFLFDRYQVKSGENISELDSKFKILLLQQGELKSARGEKFVPGKIYTNLKEKLQATQSSVVYGLSDANSKVALEQCPQLDRWSNPSEVLPSTDSRNSSNAWVKPSGINNERKVIPFPSQTKHEEDKRVLFPSPKVKAKQFWQSFTKSYPFFAQQSGSDCGAACLVMIARHWGQRLSANRVREIANVNREGASLRSLAAAAESVGFASRPVKATLDRLAQQTLPAVAHWEGKHYIVVYEITPKKVIVCDPAIGQRSFSHSEFKAKWTGYALLLQPTVKLKDNEGKSTGLWKYLELVKPHWKILVEIFVASLVIQVFGLITPLFTQLLLDKVIVQGSIVTLNAVGLGLIIFGLFRIAVNAVRQYLLSHTANRISVSMLVGFLKHTFRLPLSYFESRYVGDITSRIQENQSIQSFLTGETLSIILDLLTVIVYMGMMFWYNWQLAILVLLIVPPFFILALASTSILRKMSREIFNASAEQSSYLIQSLTGIRSVRSMAIEQTVRWRWEELLNQLIKIDFRAEVIGLRLQIISSCIDTISTTGLLWYGSYLVIDGQLTIGQLIAFNMLLGNVLSPFKRLSMVWNDFQEILISAERLNDVLEAEPEEDLILKPRKPISRLRGYIRFENVTFRYHPESEKNVLENLNFEIHPEQMVAVVGRSGSGKTTLSKLILGLYPATSGKVIIDGHDVSKIALKSLRRQIGVVDQDTFLFGGTIRENISLAHPEATLEEIIEAACLAGADEFIQQLPMGYETQIGEGGGMLSGGQRQRLAISRALLGNPRFLIFDEATSSLDAESERIIQHNLKTILKGRTSLIIAHRLSTVRNADLLLVLDQGVLVESGTHDELIAKKGHYYYLNQQQLSQVG
>NC_019678.1|WP_015119474.1|4292768_4294319_+|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit
MTHTPLKNPEPDEYQSYTSNPVDTSSPSIDERDRNQEDITEENSGIFYGTEELLDALPRVWTRSLLYVLVVFAAVGVPLSMVSRVDETGTAKGKVEPLGATRKLDSIAGGKVKAVNVKEGDKVQKGQILLELDSKVLESDINEAKEKLSGLKKQQSQLELLKNQLQLTIDTQRQQNESQALEKKAQVSQAQTDLYARQSNYNLQKLEKKAQVERAKQQIKIFENEQQSAQNRLFIDTKQVERFSKLLKDGAVSASQIDGLKKEQQESKRLYTKAASDIKQAELSLTEEFNNYLATMNQLESDIEQAKLRVQEEKSNYQSLVNAGTLALLRAQEQFKDLQGQLDLLKSQIAQTSTQLKSLNIQLQQRTVRSPMDGVIFELPVSKPGQVLQPGQRIARIAPKGKEMVIKAQMPSSETGFLKVGMPVKIKFDAYPFQEYGIGKGKVKWISPDSKQAAQGGAEIYELEIALDKHYIQNGDKRINLTAGQSATAEVIVRRRRVIDLLLDPFKKLQKGGLEL
>NC_019678.1|WP_015119475.1|4294380_4295163_+|peptidylprolyl-isomerase
MSKALHISATEVIHNLKISCQIPDVIEAIAKRNVILDAAAEAGIVVEDEELQQEGDRLRFAKKLVKATETWAWLKKHHLTLDNFEELAFNSVLSQKLAHHLFDSKVEPLFYQNQLDYIAAVTYEVILDDWDLALELFFAVQELEVTFQEIAREYISDPDLRRAGGFKGIQQRTDFRPEVAAAVFAASPPGIIKPVTTPKGIHLIWVEEIIQPKLDEQLHEKIVMELFDIWLQQQTDQMEISTQLDRFADTNIPEKVLNPV
>NC_019678.1|WP_015119476.1|4295509_4295812_+|hypothetical-protein
MLISDLNNLETVNGNEVVGGFRNANKKEKLSRDIKTSLKNDVNSVVRVVGNAADAQADASALGRNTVTNTYTDTTVVQGKGSSSTSGSTSATSGFFFKKY
>NC_019678.1|WP_015119477.1|4296035_4296332_+|hypothetical-protein
MSKIRIHELSLCEKEDSELHDVVGGESSFLKYDDSFFFGKRPVGYYTPEAVIYPTTDAYVESVEETVVNKDGYYGQAKVVKGRTNGRKFVRAFSSARA
>NC_019678.1|WP_015119478.1|4296504_4296708_+|hypothetical-protein
MEQEEIVIKKIVSADGKVIAEATSRAKASGDNTSVRARVSSSSSSSSSSSSSSSSRSSSSSSSSSSC

Crispr_ID: NC_019678_19

• CRISPR_ID: NC_019678_19
• CRISPR_location: 4390690-4391013
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 4 spacers

Consensus repeat of NC_019678_19

Consensus_repeat	Method
AGTTTCAATCCCTAATAGGGATTTATGTTAGTTTCAACT	CRISPRCasFinder
GTTTCAATCCCTAATAGGGATTTATGTNAGTTTCAACT	CRT
AGTTGAAACTAACATAAATCCCTATTAGGG----------ATTGAAAC	PILER-CR

spacers of NC_019678_19

>19.1|4390729|32|NC_019678|CRISPRCasFinder
GGGACTTTATATTGCTGTGGCAAAAAAGCCTT
>19.2|4390800|33|NC_019678|CRISPRCasFinder
TTTAAATGCAGTACCCCTACTTCTTCTAAATCC
>19.3|4390872|32|NC_019678|CRISPRCasFinder
TACCACAAAGTGTTGCCTGTAGTTATGTGGTA
>19.4|4390943|32|NC_019678|CRISPRCasFinder
TTAATAAATTGTCGAATGTTTACAGAAGGTGT
>19.5|4390729|33|NC_019678|CRT
GGGACTTTATATTGCTGTGGCAAAAAAGCCTTT
>19.6|4390800|34|NC_019678|CRT
TTTAAATGCAGTACCCCTACTTCTTCTAAATCCA
>19.7|4390872|33|NC_019678|CRT
TACCACAAAGTGTTGCCTGTAGTTATGTGGTAA
>19.8|4390943|33|NC_019678|CRT
TTAATAAATTGTCGAATGTTTACAGAAGGTGTA
>19.9|4390730|33|NC_019678|PILER-CR
GGGACTTTATATTGCTGTGGCAAAAAAGCCTTT
>19.10|4390801|34|NC_019678|PILER-CR
TTTAAATGCAGTACCCCTACTTCTTCTAAATCCA
>19.11|4390873|33|NC_019678|PILER-CR
TACCACAAAGTGTTGCCTGTAGTTATGTGGTAA
>19.12|4390944|33|NC_019678|PILER-CR
TTAATAAATTGTCGAATGTTTACAGAAGGTGTA

CRISPR arrays and Neighbor proteins around NC_019678_19

CRISPR arrays

The CRISPR arrays of NC_019678_19

>merge|NC_019678|19|4390690-4391013|CRISPRCasFinder,CRT,PILER-CR
CATTTCAATCCCTCATAGGGATTTATGTGAGTTTCAACTGGGACTTTATATTGCTGTGGCAAAAAAGCCTTTGTTTCAATCCCTAATAGGGATTTATGTGAGTTTCAACCTTTAAATGCAGTACCCCTACTTCTTCTAAATCCAGTTTCAATCCCTAATAGGGATTTATGTTAGTTTCAACTTACCACAAAGTGTTGCCTGTAGTTATGTGGTAAGTTTCAATCCCTAATAGGGATTTATGTTAGTTTCAACTTTAATAAATTGTCGAATGTTTACAGAAGGTGTAGTTTCAATCCCTAATAGGGATTTATGTTAGTTTCAACT

>NC_019678|19|17|4390690-4391013|CRISPRCasFinder
CATTTCAATCCCTCATAGGGATTTATGTGAGTTTCAACT	GGGACTTTATATTGCTGTGGCAAAAAAGCCTT
TGTTTCAATCCCTAATAGGGATTTATGTGAGTTTCAACC	TTTAAATGCAGTACCCCTACTTCTTCTAAATCC
AGTTTCAATCCCTAATAGGGATTTATGTTAGTTTCAACT	TACCACAAAGTGTTGCCTGTAGTTATGTGGTA
AGTTTCAATCCCTAATAGGGATTTATGTTAGTTTCAACT	TTAATAAATTGTCGAATGTTTACAGAAGGTGT
AGTTTCAATCCCTAATAGGGATTTATGTTAGTTTCAACT

>NC_019678|19|5|4390691-4391013|CRT
ATTTCAATCCCTCATAGGGATTTATGTGAGTTTCAACT	GGGACTTTATATTGCTGTGGCAAAAAAGCCTTT
GTTTCAATCCCTAATAGGGATTTATGTGAGTTTCAACC	TTTAAATGCAGTACCCCTACTTCTTCTAAATCCA
GTTTCAATCCCTAATAGGGATTTATGTTAGTTTCAACT	TACCACAAAGTGTTGCCTGTAGTTATGTGGTAA
GTTTCAATCCCTAATAGGGATTTATGTTAGTTTCAACT	TTAATAAATTGTCGAATGTTTACAGAAGGTGTA
GTTTCAATCCCTAATAGGGATTTATGTTAGTTTCAACT

>NC_019678|19|6|4390692-4391013|PILER-CR
TTTCAATCCCTCATAGGGATTTATGTGAGTTTCAACTG	GGACTTTATATTGCTGTGGCAAAAAAGCCTTTG
TTTCAATCCCTAATAGGGATTTATGTGAGTTTCAACCT	TTAAATGCAGTACCCCTACTTCTTCTAAATCCAG
TTTCAATCCCTAATAGGGATTTATGTTAGTTTCAACTT	ACCACAAAGTGTTGCCTGTAGTTATGTGGTAAG
TTTCAATCCCTAATAGGGATTTATGTTAGTTTCAACTT	TAATAAATTGTCGAATGTTTACAGAAGGTGTAG
TTTCAATCCCTAATAGGGATTTATGTTAGTTTCAACT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015119557.1|4396940_4397363_-|TerB-family-tellurite-resistance-protein	unknown	unknown	gnl|CDD|143581
NC_019678.1|WP_015119556.1|4395841_4396558_-|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	gnl|CDD|131644
NC_019678.1|WP_083894134.1|4381135_4381399_-|c-type-cytochrome	unknown	unknown	gnl|CDD|177085
NC_019678.1|WP_015119543.1|4382107_4382632_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_019678.1|WP_015119559.1|4399082_4400519_-|glycogen-debranching-protein	unknown	unknown	gnl|CDD|372373
NC_019678.1|WP_015119561.1|4403326_4403731_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119548.1|4386944_4387316_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119545.1|4383254_4384619_-|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase	unknown	unknown	gnl|CDD|223841
NC_019678.1|WP_015119541.1|4380066_4380948_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_019678.1|WP_015119544.1|4382810_4383146_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119553.1|4391887_4392373_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl|CDD|223872
NC_019678.1|WP_015119547.1|4386339_4386936_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NC_019678.1|WP_015119546.1|4385011_4385455_-|tellurite-resistance-TerB-family-protein	unknown	unknown	gnl|CDD|143580
NC_019678.1|WP_044291007.1|4387604_4388414_-|ion-transporter	unknown	unknown	gnl|CDD|369572
NC_019678.1|WP_015119558.1|4397410_4398790_-|16S-rRNA-(cytosine(967)-C(5))-methyltransferase	unknown	unknown	gnl|CDD|237856
NC_019678.1|WP_015119555.1|4395530_4395740_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119550.1|4388551_4389481_+|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl|CDD|224214
NC_019678.1|WP_015119560.1|4401998_4403066_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_157229430.1|4392797_4395326_+|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl|CDD|273955
NC_019678.1|WP_015119552.1|4391251_4391800_-|NUDIX-hydrolase	unknown	unknown	gnl|CDD|239516

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015119559.1|4399082_4400519_-|glycogen-debranching-protein	gnl|CDD|372373	pfam12899, Glyco_hydro_100, Alkaline and neutral invertase. This is a family of bacterial and plant alkaline and neutral invertases, EC:3.2.1.26, previously known as Invertase_neut pfam04853.	0
NC_019678.1|WP_015119556.1|4395841_4396558_-|PEP-CTERM-sorting-domain-containing-protein	gnl|CDD|131644	TIGR02595, conserved_hypothetical_protein, PEP-CTERM protein-sorting domain. This model describes a 25-residue domain that includes a near-invariant Pro-Glu-Pro (PEP) motif, a thirteen residue strongly hydrophobic sequence likely to span the membrane, and a five-residue strongly basic motif that often contains four Arg residues. In nearly every case, this motif is found within nine residues, and usually within five residues, of the extreme C-terminus of the protein. Proteins with this motif typically have signal sequences at the N-terminus. This region appears many times per genome or not at all, and co-occurs in genomes with a proposed protein-sorting integral membrane protein we designate exosortase (see TIGR02602). PEP-CTERM proteins frequently are poorly conserved, Ser/Thr-rich proteins and may become extensively modified proteinaceous constituents of extracellular material in bacterial biofilms. [Cell envelope, Surface structures].	4.32698e-05
NC_019678.1|WP_083894134.1|4381135_4381399_-|c-type-cytochrome	gnl|CDD|177085	CHL00183, petJ, cytochrome c553; Provisional.	7.25973e-41
NC_019678.1|WP_015119543.1|4382107_4382632_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.22927e-12
NC_019678.1|WP_015119545.1|4383254_4384619_-|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase	gnl|CDD|223841	COG0770, MurF, UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane].	4.62221e-157
NC_019678.1|WP_015119541.1|4380066_4380948_-|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	3.62875e-17
NC_019678.1|WP_157229430.1|4392797_4395326_+|PBP1A-family-penicillin-binding-protein	gnl|CDD|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NC_019678.1|WP_015119553.1|4391887_4392373_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl|CDD|223872	COG0801, FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Coenzyme metabolism].	1.27766e-61
NC_019678.1|WP_015119550.1|4388551_4389481_+|YihY/virulence-factor-BrkB-family-protein	gnl|CDD|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	7.73646e-60
NC_019678.1|WP_015119546.1|4385011_4385455_-|tellurite-resistance-TerB-family-protein	gnl|CDD|143580	cd07176, terB, tellurite resistance protein terB. This family contains uncharacterized bacterial proteins involved in tellurium resistance. The prototype of this CD is the Kp-terB protein from Klebsiella pneumoniae, whose 3D structure was recently determined. The biological function of terB and the mechanism responsible for tellurium resistance are unknown.	1.31544e-21
NC_019678.1|WP_044291007.1|4387604_4388414_-|ion-transporter	gnl|CDD|369572	pfam07885, Ion_trans_2, Ion channel. This family includes the two membrane helix type ion channels found in bacteria.	2.01067e-06
NC_019678.1|WP_015119558.1|4397410_4398790_-|16S-rRNA-(cytosine(967)-C(5))-methyltransferase	gnl|CDD|237856	PRK14901, PRK14901, 16S rRNA methyltransferase B; Provisional.	0
NC_019678.1|WP_015119557.1|4396940_4397363_-|TerB-family-tellurite-resistance-protein	gnl|CDD|143581	cd07177, terB_like, tellurium resistance terB-like protein. This family consists of tellurium resistance terB proteins, N-terminal domain of heat shock DnaJ-like proteins, N-terminal domain of Mo-dependent nitrogenase-like proteins, C-terminal domain of ABC transporter ATP-binding proteins, C-terminal domain of serine/threonine protein kinase, and many hypothetical bacterial proteins. The function of this family is unknown.	9.21527e-09
NC_019678.1|WP_015119547.1|4386339_4386936_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	8.05308e-23
NC_019678.1|WP_015119552.1|4391251_4391800_-|NUDIX-hydrolase	gnl|CDD|239516	cd03424, ADPRase_NUDT5, ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, for its activity. It also contains a highly conserved 23-residue Nudix motif (GX5EX7REUXEEXGU, where U = I, L or V) which functions as a metal binding site/catalytic site. In addition to the Nudix motif, there are additional conserved amino acid residues, distal from the signature sequence, that correlate with substrate specificity. In humans, there are four distinct ADPRase activities, three putative cytosolic enzymes (ADPRase-I, -II, and -Mn) and a single mitochondrial enzyme (ADPRase-m). Human ADPRase-II is also referred to as NUDT5. It lacks the N-terminal target sequence unique to mitochondrial ADPRase. The different cytosolic types are distinguished by their specificities for substrate and specific requirement for metal ions. NUDT5 forms a homodimer.	5.11604e-53

Protein sequences

>NC_019678.1|WP_015119550.1|4388551_4389481_+|YihY/virulence-factor-BrkB-family-protein
MNLKQIWRLLKETFKEWNEDKASRLAAALSYYTIFSLAPLLIITIAIAGAVFGDDAARGEIVRQIQGLVGKDGAEVIQTALENAQKPDTRNIASIISIAVLLFGASNVFAQIQDALNTIWEVQPKPGRSLIQTLRKRFLSFAMVGGVGFLLLVSLIVNTGLAAMVNYFSGLVPGFDLLWQIGNFIISFAVITVLFAIIYKFMPDVKIDWDDVWVGSAITSLLFVIGKSLLGLYLGNGSFGSAYGAAGSLIVVLAWINYAAQIIFFGAEFTQVYASKYGSRIVPDENAMRVPEIDRAKQGMNRRNSPKRS
>NC_019678.1|WP_044291007.1|4387604_4388414_-|ion-transporter
MSQMNPTEKSELERELTDFVQQLDDWLEMPMVVLGFVWLALLVIELIWGMIPLVDAISTTIWILFIFDFFLRFSLSPRKLKFLKNNWLIGISLLLPALRIFRFVRVLRLARVARATRSLRLLRIVGSLNRGMRALRATMSRRNFGYVLGLTLIVTFVGAAGMYAFESNLANGEGIKSYSNALWWTAMLMITYGGDYSPQTPEGRALCFILALYAFTVFGYFTAAIATFFIGRDAEDEETSVASSQSIIALHEEIKALRAEIQAMKNGNG
>NC_019678.1|WP_015119548.1|4386944_4387316_-|hypothetical-protein
MDTATCPRCKQNVNSQAVTCPYCRTPLKAYGHPGIPLHRAQGDDYLCETCTYHLDDTCNYSKRPHATECTLYQNEAERNLELQEKNQKPDLNTSVNNWIRRNQSLLLIFGLLLICLLLVLSRS
>NC_019678.1|WP_015119547.1|4386339_4386936_+|GNAT-family-N-acetyltransferase
MNLARDIISKIFQQGLQADGCLLSVEIKCDRLLLKSISLAYKKPIFETFTEEITTYMYPRPAKNVTETASFIKNSLEGMKNEHELILVILKKNSQEFLGCAGIHRINTKHPEFGIWLKKAAHRQGYGLEAIAAMKNWCETHLESEYFTYPVDEENYPSRRIPEKLGGEIMRTYQKRNLSGRILNLVEYRIQGKVSSEQ
>NC_019678.1|WP_015119546.1|4385011_4385455_-|tellurite-resistance-TerB-family-protein
MSLFDRASSSQSRVKNALSPAEALASIALIAVAPDGNLSSKQTHDIHEALSSLKLLCSYSTEDMQSMFDVLSGIIRHEGVNNLFDSAKDSLSEELRETAFAVATDLILVDGILVEEQDFLVELYQALRIRGEIGQKIIEVMFIKNRG
>NC_019678.1|WP_015119545.1|4383254_4384619_-|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase
MPCSATLKQLVELLGAQSANLSETALAESFFGIQTDSRIIKPGEVFVAFRGEKFDGHKFVATAIEKGAIAAIVDFEYENSQLPVLKVTNTLETYQKIAQWWRNQFSIPIIGVTGSVGKTTTKELIAGVLSTQGRVHKTYANFNNEIGVPKTLLELVAEHDYAVIEMAMRGLGQIAELTQITRPTIAVITNVGTAHIELLKSEEAIAQAKCELLAEMPKDGVAILNYDNPLLMKTAAKVWQGKVISFGFTGGDIHGKLIDNYTLEIAGLRLPLPMPGRHIGANYMAALAVAKVLNIDWSNFKNGVAVDMPGGRSQQFTLLNDVLILDETYNAAPEAMVAALNLLAETPGKRRIAVLGAMKELGEKSEQLHQQIGETARSLNLDALMVLVDCADAEALAKSAEGIPIQCYSNHEELATGLKQYLQEGDRILFKAAHSVGLDKVVSQLRNDFSKSAA
>NC_019678.1|WP_015119544.1|4382810_4383146_+|hypothetical-protein
MLDINTITEFSRNHCVTICAFLVPANLIATLSTMILAALHRPLAQVLQSTVVATFFAAVMIMHVYTWFSIGVVAVPTYILLWLAITCLFTNLGAFLFQRRYIRTYFLIGNR
>NC_019678.1|WP_015119543.1|4382107_4382632_-|GNAT-family-N-acetyltransferase
MSLSISQVTVSQIPALHQILVECGLDLQKRCNLCYWVPPYPLEKMLKDARNMDLYAIKLDSELIGTFTIETKMPSGYLKYGNINWQNPGLSAFYMHRLAVLPLFQAKGIGTWCLQQIENLAINRNYSAVRLDAVKTNQKLLKFYEKSGYKKVGEIIFNPEDKYEDAFVFEKVVA
>NC_019678.1|WP_083894134.1|4381135_4381399_-|c-type-cytochrome
MAASHEEGAQLFKQNCAACHAGGGNLVAANKTLKKEALEKYDMYSKEAIVYQVTNGKNAMPAFGKRLSSEQIESLAGYVLAQADKGW
>NC_019678.1|WP_015119541.1|4380066_4380948_-|tetratricopeptide-repeat-protein
MVIVLMLFSFPAGALGLPQGSSQDLFKLGISQLENDEYTTAIENFTQAIEINPNYAKAYYNRCLAFLNSSDYQHAIADCDTALEQSPDFFEAYLNRGLAYYNLQLPAAAIADFNYFLSIFPDDFRAYYDRGLAYFDEEIYQKAVGDYSRALELIPPTNTQHIAAIYNNLGLTYLQLDEFELAIKDFSQAISAGVEDASYYCNRGYAFRQLEKYKQAIDDFTESIRLNRRQSAAYIGRGFAFYSSGKQQEAREDFLQAAEYFRDCGKMQQFHQIVYLIKIIRHKSPFIYKALLT
>NC_019678.1|WP_015119552.1|4391251_4391800_-|NUDIX-hydrolase
MSLGRELPQLLKQRLLYKGRKFDFEVNRLRLPNKSEGDWECIRHPGGALAVPVTPEGKLILLRQYRFAVGGRLLEFPAGTVEEGESPFQTIQREIQEETGYRARKWQKLGNFFLAPGYSDEIIYAYLAEDLEKLEVPPNLDEDEDIEVLFFTPAELEKAILEGDAVDSKTISSLILARPYLS
>NC_019678.1|WP_015119553.1|4391887_4392373_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MHDSVIALGSNIGDSLTILEAAVKTLHKIPGITGSMKSSWYQTKAIGPPQPDYLNGCISLRADIEPFKLLEILLQIENQFGRERKQRWGARTLDLDLLLYDDLILHTPTLQIPHPRMTQRAFVLVPLAEIVPHWIEPISGRTIKELLDDVDCSDVCLLTSN
>NC_019678.1|WP_157229430.1|4392797_4395326_+|PBP1A-family-penicillin-binding-protein
MTKQLSPPPHWVQVVRDSEPSSEPTDKSSPKTLKGKAKLLLGNTRQFLGDAKKVSNKVLDKLPGKGKPLYRRYWFLTTLGVSGSIMAVSYGVWSIDKTLPSKDQLTAASRENTLTIKAGNGAILYQQGEATREKLKIKQIPKKLQQAFIASEDRRFAEHGGIDPQGILRAATSNLRSRDVVEGGSTITQQLARILFLNRNKTVNRKLQEIRLAQKLEEELTKDEILERYLNLVYLGSGAYGVADAAWVYFSKPLADLSLGEMATIAGLAPAPNVFSPAENAEAAKRRRNLVLQRMLDDGFITAAEKQKAASESLAVKTNFPKRHQIQAPYFISYIQKELPKYVEKDVLEAGGLVVETSLNPTWQKKAEAAVDRTLRNQGRWQRFKQAAMVAIDPRNGEIKAMVGGKDFGKNKFNRVTQAQRQPGSTFKGFVYAAAVAAGKSPMDGYLDAPIVVDGYEPKNYDKGFRGWINMRDALTKSINIVAVRILMKVGYQPTIDLARKMGIESEIKPVISMALGSNEVNLLELTSAYGTFANEGMRVKPHGITRVLSRNGEVIWSADFKGKRALDADSAAITTWMLRNVVTSGTATRAQIGRPAAGKTGTTDEARDLWFVGFIPQLVTGVWLGNDNNKPTYGDSTTAAYTWRQFMKEAVKGMPVEKFPKRPKLSGRKASIKVKPIKPKRFITKAIPKKGSDSDDDNETTTNRSSSRRRRRRSTTTNSSTSGGNRRTRSRRTRRRRSTTRTQQKSTTRTRRRSNVNSGSSKRRSSPSRSQRRRRTTKPTSTRRNTRRSSPPVRKKRSAPVRRKRSVAPKPKKRSAPAPARKKAAPSSSGSSWRDRLKPGS
>NC_019678.1|WP_015119555.1|4395530_4395740_+|hypothetical-protein
MSLLMQAGNEGFQFPLAFTLVYVVGFIAAVGIGSIAWYNSKRPAGWESKKRPDFVPEVEKEDNPGLGGK
>NC_019678.1|WP_015119556.1|4395841_4396558_-|PEP-CTERM-sorting-domain-containing-protein
MFSNIFKKAALFGASTVASVAVTGTMMASSAQAATMTYRSEFSVTSNSLNNADLITGHFDFSKTEENNGEFSYKVTSFNANVLNERITLSDMRANQNPFLAINQTFVPRKYQTILPSVLAGESPNYTGDGDFGEGNLSYTFGFDLGNPNFQPDDFDFAFSSEDLDNVATLASNVITSVDPSFTQFYVPFALRQGGQINITTKAVPEPATIFALGAVGVGLTATRRKRASKKIKQKTAA
>NC_019678.1|WP_015119557.1|4396940_4397363_-|TerB-family-tellurite-resistance-protein
MVSNPEIKQLLKILIAAAWIDGKVQPEEREYLQQIAKSKDIATDPDIKPWLYGLVPIKPEECYQWVEEYLGTSPSVEDCQNLIQEIGGLIYSDGEVAIEEAKLLAKIQDLSAQSESKQGKLNIILKQVQKMYRRWVEVQN
>NC_019678.1|WP_015119558.1|4397410_4398790_-|16S-rRNA-(cytosine(967)-C(5))-methyltransferase
MTTSRQQALLALKDVHKGAYADVALDRVLRKVDLPNNERRLVTELVYGSVRRQRTLDAIIDKLARKKSHQQPLLLRCILHLGLYQLQFQERIPDSAAVNTTVQLAKDNGFSGLSGFVNGLLRSYIRLQEELQQKEGEETKTNKIIPIKLPEKQSERLGILYSFPDWVVNIWVEQFGFSETEKLCEWMNQTPNIDLRVNQLCSSIEEVETALKNQGISSQRIPNLPQALRLLNSPGAIKNLPGFNEGWWTVQDSSAQLVSYLLNPQPHEVIIDACAAPGGKTTHIAELMGDTGQIYACDRTESRLRKLQQNTQRLNLKSVEVCLGDSRSLTQFEKSADKVLLDVPCSGLGTLHRHADARWRQTPDNIKELCVLQAELLLHSSTFVKDSGSLVYSTCTLHPDENEGAIKSFLESNSNWEIQSPDTYSAIHEYATSEGWIKVLPHKHNMDGFFMVRLRKKHN
>NC_019678.1|WP_015119559.1|4399082_4400519_-|glycogen-debranching-protein
MQLEDSKAIQKVEEEAWEVLQKTIIYFKGRPIGTVAALDGSVDALNYDQCFVRDFASSALLFLIKGETDIVRNFLEETLKLQPTDNQLDAYKPGQGLMPASFKVVSKNGEEYLEADFGEHAIARVTPIDSCLWWLIILRAYVVATKDYSLIYQPEFQTGIGLILELCLATRFDMYPTLLVPDGACMIDRRLGIYGHPLEIQSLFYAALRAAREMLICHGNQDLVIAIDNRLPILRAHIRKHYWIDIKRLNAIYRYKGEEYGKEAVNQFNIYVDSLPYYELDKWLPKKGGYLAGNVGPSQLDTRFFSLGNLMAVICDLASEEQSDAIMTLIEKRWEDLVGDMPMKITFPALENEEYRLITGCDPKNIPWSYHNGGNWPVLMWMLTAAAIKTNKICIAERAIHIAQLRLQEDEWPEYYDGKRGRLIGKQSRKYQTWTIAGLLLAKEMIKEPSHLSLMSFEPFTIEEASRACEFEIDSFDA
>NC_019678.1|WP_015119560.1|4401998_4403066_+|hypothetical-protein
MLKASEITKTPSSERLLNLWARRYTPEVSFLLGDSSSCDELLKAAAPQGRESTTNKLKDKMLDINCQMGWIQTKNLYSYIPNVLDLTEARRITKFAFRVYRKLLEIYQQQSSKIEVENNSLSQWVIPAVEELAYALEPILIVFQEQHVASKDWRSLGFMTSQLNFTNKLMLKRLTKVEQVLLAPYFKFVEEQVAMPWQRVCSHAANYELNSPELKLVEQMMPNSPEIAQSVYRKLTELLPNNRSRRGKLTDNGISHSCIRDLNMFQAYILLCFLEQNMEPIEQELVPLCAMVVEGVEIKWELTKNWCEVLANEIESRLDSAQKDLIKPYTQGMKQAFFKERRSLGCKEEMAAEVV
>NC_019678.1|WP_015119561.1|4403326_4403731_-|hypothetical-protein
MTKNTESIKDKAEGAALVAGGTAAGAGASAVVGGMGLVGGFGGIAIGVAPIAAAGAVVGSAAYGAKKAIEEQDATALGAVAGGAAAGAGVAATVGGMGLAVGGTAVAIGTAPVVAAGAVVGLATYGLNKWFKKK

Crispr_ID: NC_019678_20

• CRISPR_ID: NC_019678_20
• CRISPR_location: 4488974-4489073
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 1 spacers

Consensus repeat of NC_019678_20

Consensus_repeat	Method
TTGGAATTAGTAAATCATTAAGC	CRISPRCasFinder

spacers of NC_019678_20

>20.1|4488997|54|NC_019678|CRISPRCasFinder
ACCAATAGAATCAGGAATTGCCGCAAGCGTCACACAACTCTGGTGGTGCGTGAA

CRISPR arrays and Neighbor proteins around NC_019678_20

CRISPR arrays

The CRISPR arrays of NC_019678_20

>merge|NC_019678|20|4488974-4489073|CRISPRCasFinder
TTGGAATTAGTAAATCATTAAGCACCAATAGAATCAGGAATTGCCGCAAGCGTCACACAACTCTGGTGGTGCGTGAATTGGAATTAGTAAATCATTCAGC

>NC_019678|20|18|4488974-4489073|CRISPRCasFinder
TTGGAATTAGTAAATCATTAAGC	ACCAATAGAATCAGGAATTGCCGCAAGCGTCACACAACTCTGGTGGTGCGTGAA
TTGGAATTAGTAAATCATTCAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015119615.1|4486491_4487796_+|threonine-synthase	unknown	unknown	gnl|CDD|236065
NC_019678.1|WP_044291972.1|4463563_4463821_+|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340452
NC_019678.1|WP_015119618.1|4491196_4491544_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_083894074.1|4468389_4471989_-|DUF11-domain-containing-protein	unknown	unknown	gnl|CDD|375050
NC_019678.1|WP_015119622.1|4495268_4495703_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119624.1|4496364_4496727_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119606.1|4463207_4463396_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_157229431.1|4464168_4466925_-|DUF11-domain-containing-protein	unknown	unknown	gnl|CDD|275067
NC_019678.1|WP_015119626.1|4497884_4499372_+|carotene-isomerase	unknown	unknown	gnl|CDD|131777
NC_019678.1|WP_015119620.1|4492312_4492828_-|NINE-protein	unknown	unknown	gnl|CDD|222840
NC_019678.1|WP_015119617.1|4489119_4491117_+|iron-uptake-porin	unknown	unknown	gnl|CDD|335962
NC_019678.1|WP_015119621.1|4493566_4494643_+|magnesium-protoporphyrin-IX-monomethyl-ester-(oxidative)-cyclase	unknown	unknown	gnl|CDD|237458
NC_019678.1|WP_044291982.1|4487972_4488248_+|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340594
NC_019678.1|WP_015119610.1|4472816_4474979_-|OmpA-family-protein	unknown	unknown	gnl|CDD|143586
NC_019678.1|WP_044291013.1|4462131_4463064_-|histone-deacetylase	unknown	unknown	gnl|CDD|212518
NC_019678.1|WP_015119619.1|4491821_4492316_+|DUF2996-domain-containing-protein	unknown	unknown	gnl|CDD|371420
NC_019678.1|WP_015119613.1|4481804_4482374_-|hypothetical-protein	unknown	unknown	gnl|CDD|227063
NC_019678.1|WP_015119625.1|4496818_4497469_-|uracil-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234653
NC_019678.1|WP_015119623.1|4495882_4496158_-|YggT-family-protein	unknown	unknown	gnl|CDD|376765
NC_019678.1|WP_015119612.1|4480085_4481660_-|DUF11-domain-containing-protein	unknown	unknown	gnl|CDD|273634

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015119615.1|4486491_4487796_+|threonine-synthase	gnl|CDD|236065	PRK07591, PRK07591, threonine synthase; Validated.	0
NC_019678.1|WP_044291972.1|4463563_4463821_+|MoaD/ThiS-family-protein	gnl|CDD|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	7.81334e-24
NC_019678.1|WP_015119621.1|4493566_4494643_+|magnesium-protoporphyrin-IX-monomethyl-ester-(oxidative)-cyclase	gnl|CDD|237458	PRK13654, PRK13654, magnesium-protoporphyrin IX monomethyl ester cyclase; Provisional.	0
NC_019678.1|WP_083894074.1|4468389_4471989_-|DUF11-domain-containing-protein	gnl|CDD|375050	pfam17210, SdrD_B, SdrD B-like domain. This family corresponds to the B-like domain from the SdrD protein. This domain has three calcium binding sites within a greek key beta sandwich fold.	2.82815e-09
NC_019678.1|WP_157229431.1|4464168_4466925_-|DUF11-domain-containing-protein	gnl|CDD|275067	TIGR04226, Fimbrial_subunit_type_2, fimbrial isopeptide formation D2 domain. The Streptococcus Pneumoniae pilus backbone protein, RrgB, has three tandem domains with Lys-to-Asn isopeptide bonds, but these three regions are extremely divergent in sequence. This model represents the homology domain family of the D2 domain. It occurs just once in many surface proteins but up to twenty times in some pilin subunit proteins. Three of every four members have the typical Gram-positive C-terminal motif, LPXTG, although in many cases this motif may be involved in pilin subunit cross-linking rather than cell wall attachment. Proteins with this domain include fimbrial proteins with lectin-like adhesion functions, and the majority of characterized members are involved in surface adhesion to host structures.	8.22623e-11
NC_019678.1|WP_015119626.1|4497884_4499372_+|carotene-isomerase	gnl|CDD|131777	TIGR02730, Carotenoid_isomerase, carotene isomerase. Members of this family, including sll0033 (crtH) of Synechocystis sp. PCC 6803, catalyze a cis-trans isomerization of carotenes to the all-trans lycopene, a reaction that can also occur non-enzymatically in light through photoisomerization. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_019678.1|WP_015119620.1|4492312_4492828_-|NINE-protein	gnl|CDD|222840	PHA01886, PHA01886, TM2 domain-containing protein.	2.88096e-14
NC_019678.1|WP_015119617.1|4489119_4491117_+|iron-uptake-porin	gnl|CDD|335962	pfam04966, OprB, Carbohydrate-selective porin, OprB family.	1.81929e-26
NC_019678.1|WP_044291982.1|4487972_4488248_+|MoaD/ThiS-family-protein	gnl|CDD|340594	cd17074, Ubl_CysO_like, ubiquitin-like (Ubl) domain found in Mycobacterium tuberculosis CysO and similar proteins. CysO, also termed 9.5 kDa culture filtrate antigen cfp10A, together with CysM (Cysteine synthase M), forms a protein complex CysM-CysO that represents a new cysteine biosynthetic pathway in Mycobacterium tuberculosis. The replacement of the acetyl group of O-acetylserine by CysO thiocarboxylate to generate a protein-bound cysteine is catalyzed by CysM in a pyridoxal 5?-phosphate (PLP)-dependent manner. The family also includes QbsE that functions as the sulfide donor for the biosynthesis of thioquinolobactin in Pseudomonas fluorescens. A JAMM motif protein QbsD catalyzes removal of the carboxy-terminal dipeptide from QbsE. Both CysO and QbsE are similar to prokaryotic sulfur carrier proteins such as ThiS and MoaD, containing the beta-grasp ubiquitin-like fold.	4.2368e-49
NC_019678.1|WP_015119610.1|4472816_4474979_-|OmpA-family-protein	gnl|CDD|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	3.94469e-34
NC_019678.1|WP_044291013.1|4462131_4463064_-|histone-deacetylase	gnl|CDD|212518	cd09992, HDAC_classII, Histone deacetylases and histone-like deacetylases, classII. Class II histone deacetylases are Zn-dependent enzymes that catalyze hydrolysis of N(6)-acetyl-lysine residues of histones (EC 3.5.1.98) and possibly other proteins to yield deacetylated histones/other proteins. This group includes animal HDAC4,5,6,7,8,9,10, fungal HOS3 and HDA1, plant HDA5 and HDA15 as well as other eukaryotes, archaeal and bacterial histone-like deacetylases. Eukaryotic deacetylases mostly use histones (H2, H3, H4) as substrates for deacetylation; however, non-histone substrates are known (for example, tubulin). Substrates for prokaryotic histone-like deacetylases are not known. Histone acetylation/deacetylation process is important for mediation of transcriptional regulation of many genes. Histone deacetylases usually act via association with DNA binding proteins to target specific chromatin regions. Interaction partners of class II deacetylases include 14-3-3 proteins, MEF2 family of transcriptional factors, CtBP, calmodulin (CaM), SMRT, N-CoR, BCL6, HP1alpha and SUMO. Histone deacetylases play a role in the regulation of cell cycle, cell differentiation and survival. Class II mammalian HDACs are differentially inhibited by structurally diverse compounds with known antitumor activities, thus presenting them as potential drug targets for human diseases resulting from aberrant acetylation.	1.41994e-131
NC_019678.1|WP_015119619.1|4491821_4492316_+|DUF2996-domain-containing-protein	gnl|CDD|371420	pfam11210, DUF2996, Protein of unknown function (DUF2996). This family of proteins has no known function.	1.8544e-78
NC_019678.1|WP_015119613.1|4481804_4482374_-|hypothetical-protein	gnl|CDD|227063	COG4719, COG4719, Uncharacterized protein conserved in bacteria [Function unknown].	7.86871e-35
NC_019678.1|WP_015119625.1|4496818_4497469_-|uracil-phosphoribosyltransferase	gnl|CDD|234653	PRK00129, upp, uracil phosphoribosyltransferase; Reviewed.	8.14195e-108
NC_019678.1|WP_015119623.1|4495882_4496158_-|YggT-family-protein	gnl|CDD|376765	pfam02325, YGGT, YGGT family. This family consists of a repeat found in conserved hypothetical integral membrane proteins. The function of this region and the proteins which possess it is unknown.	2.88017e-17
NC_019678.1|WP_015119612.1|4480085_4481660_-|DUF11-domain-containing-protein	gnl|CDD|273634	TIGR01451, unnamed_protein_product, conserved repeat domain. This model represents the conserved region of about 53 amino acids shared between regions, usually repeated, of proteins from a small number of phylogenetically distant prokaryotes. Examples include a 132-residue region found repeated in three of the five longest proteins of Bacillus anthracis, a 131-residue repeat in a cell wall-anchored protein of Enterococcus faecalis, and a 120-residue repeat in Methanobacterium thermoautotrophicum. A similar region is found in some Chlamydial outer membrane proteins.	1.19754e-07

Protein sequences

>NC_019678.1|WP_044291982.1|4487972_4488248_+|MoaD/ThiS-family-protein
MSVKVLVPTALQKFTNNQATLECNGSTITELFDSLEKACPGIKARLCDESGKPRRFLNLYVNSEDIRFLDGAATPLKDGDEVSIVPAVAGG
>NC_019678.1|WP_015119615.1|4486491_4487796_+|threonine-synthase
MQAATNIQNQTLTHAFHALKCKECGAEYELEAKNVCEFCFGPLEVSYDYSKLRQTVTRQTIEAGPNSIWRYRQFLPVTSENPIDVGTGMTPLVRSHRLARRLGLKKLYIKNDAVNMPTLSFKDRVVSVAMTRAKELGFTTVSCASTGNLANSTAAIAAHAGLDCCVFIPADLEAGKILGSLIYSPTLMAVKGNYDQVNRLCSEVANTHGWGFVNINLRPYYSEGSKTLGFEVAEQLGWELPDHIVAPLASGSLFGKIYKGFNEFKEVGLVKDKKVRFSGAQAEGCSPIAKAFKEGRDFIQPEKPNTIAKSIAIGNPADGIYAVEIANKTNGNIESVNDTEIIEGMKLLAETEGIFTETAGGTTIAVLKKLVEAGKIDPEETTVVYITGNGLKTQEAIQGAIGEPLTIDAKLDSFESALERSRTLERLEWQQVLV
>NC_019678.1|WP_015119613.1|4481804_4482374_-|hypothetical-protein
MKRFSIASLSAVALIAGMTFTSQIPVVANIFQGGAAVAQNAKKGQVQLRLKAEKKIITKDAQGNRKVTWQELSNGAQVGQGEVLRYSVSGANNGEKAVNNLTINQPIPRGMAYVLNSATVNEKDGAQITYSINGGKTYVKNPTIEVKLADGTVETRPAPDTAYTHVRWNFGKSLPGKGSVNGTYQVRVR
>NC_019678.1|WP_015119612.1|4480085_4481660_-|DUF11-domain-containing-protein
MRRKNKRYQIYGSSWFKRIAATVLAGSIIQSSISTFAQEVTRPTISNQATFNYNNKKNNQTFRGGVTNQVKITPVPQSSQALSDLIDPFGQILGCNGEELEDYTGFTVTLFNPDPNDPTGTEPGTVVDLTPTDDDPNTTTPQGIQPNITNANNYAVTNEPVTTANGETKRGVYNFLFDQSKNQTDVGRAYILVINPPENSAFTERRIRLEIQSLDGDILTYIATALDGQPITATGENSVQISDTQISQQAVVIDDAERIGLALALQFNLDLCSPDQIRITKTGDRATAEPGDTTVYRLSLRNTGDVGLNDIVVTDQFPLGFKFIPESVRGQIGDEEVALTTETNGSTVTFRTDTTIPVGGVLNIAYAATLTPDAVRGSGRNTATVNAERVDNNFAVKDGPATHRLEIRPGITSDCGTIIGRVFVDKNFDGEQQAGEPGVPNAVIFLENGNRITTDADGLYSVKNALPGKHTGVLDLESIPDYTLAPNVKFKERNSQSRLVNLEPGGMVRMNFGVTPNFGEDTKK
>NC_019678.1|WP_015119610.1|4472816_4474979_-|OmpA-family-protein
MYKKISKNPFYQFKQSSKFPVNIKRLLASLPVLLLTTPNIAVAQSNTAISLSVTVNSNQDGEVEADNNLTLREAIAIVNGSLSLERLSSTEQSLVSSGSNQAEIKFNLPPGQTKITLESVLPPLTNPGTIVDGTSQPGYDASKSATAEIEIPIPVVEITSAPGEQVFRGLTVAADNITVEGLSIYGFNSKHTDTASLPPGDIVVVPYNSVLITDKEKRRQGDKGSPPRNVIIKDNWLGITSEEQVPEKTSAFGVSVFNAIGTNISRNRIANHEGSAIITGKLAENTQIQSNIIVGNGIAGMPDAIRLEGKINNSQVTSNLICANDGSGVYLFKPEGSVKIQSNNIKYNGRRLRRAGVYLMGNNHEVTNNQITNQPGSGVAITAYPDSKRNVIRDNNFANIEGLSIDLNYRNTASVRDFQRGDGPNPPRNSGNRRLDSANGAINAPEFLSSEFISIDGKVNIDGKAEPGSEIDIYKVNANSKQQLDLYPAYSALGEVIARVQADEKGRFKATFTNLQPGEIISAIATQSKYGTSEPAANAIVKSVNNSQSFQKPQSPIQNPNCTSRPVAPTPIPEPPIPQPPIPEPPTPIRLSVPRNVHFALDKDFISQKSGEVLDKIAEVMEQYPNIVIELQGHTDSRASVAYNQDLARRRATNARNYLIKKGIAPERMTIRSFGERKLRTQENNVVDYARNRRVEILFFDVRGIDIEFENQEQDLQIEQ
>NC_019678.1|WP_083894074.1|4468389_4471989_-|DUF11-domain-containing-protein
MKILCKYVMCFSSLKSINKKSKKKFSQKLAAGTNLGIMSAIAKYSKVLSTSIYKLVPLSAVVLTPTFLTTAPALAAVDQVCYLISDVGGTNGNDFLVKMNTDTGQFFQISSGTGTNNIEAAAAQPGTNILFAANQESSGRLGTIDLITGAFTPRANLMGTGNGERGSINFRDPDGLAFDPTDGTLYASIRTGDGGSPPDILIKVDPVTGRHIPDAFGTNVDYVVIQPQNGRDDIDGIAIDPADGTLYGIANEGSTGGNQNLVTINKNTGATSLVGELQENGSSIDDVEDIAFDLNGKLYISTGSSGSTRNRLYDVDKNTAAVSNRRPLTIGGDYEASGCFLLPPVDVSLNKTVNDNSPNVNDIVTFTLTLTNDAAASDNAYSDVNNLVVEDVLPTNLEFDSFVTIPSGTTPTYDIGSRTVTWNVNEVLKGNNTTLQFRARVTGSGSITNSAQVTSIREFDVDSTPNNNQASEDDQSSVSLTVVAPTSTTISGTLYEDSDGGDDLDASEPKLPADITVNLLDNNNSVIKTTTTDANGAYTFTDVVNGNYKIQVDTNDSDIPNGYTLGTPNDLAVTVSGSAITNQNFGFDKTSASPPLTACPANSLLTEQTILNFQNPTPEPGTTNGDFSIGAVYRFPNVAANTDALVEVIALNNATIAQLDVTTTGLVSAFQPEVQSNSTNPSEYSVDFQIRFVQSGTSTPINLNTVLATSVDTDGDNTVVREFVQFSGNAPNSYTIETPSKLTATQIDSTTIRLESQSTDVNPGINLNTANMGSVKYDQVGVFNYRAGLIIGNNPPSNVSNQRLNSLYFECVSYNNSNSNPVVPVLDYGDAPDSYGTTSANNGANHAIVSGIHLGTAPDSETDAATPLDGSGDGAEDDGINLPTLNEGDTSYTIPAENITATGTGTLHAWLDFDKNGTFEPGEYTSVAVTNGTAANDLSWSNINAGAAGDTYARFRFTTDAGIDANTPGGGASDGEVEDYQIAIEAIANNPNILLIKRITKINNGITTNNGDNLAIYNQEDSNPYDDNKLDNPAPDPVDTDKWLGTTSDTSSTFLIGGIDGGKVEPDDEIEYTIYYLSGGDSEAKNVLFCDRVPENVTFVTNSFNGEANQATGGLQNADRGIQWLKDGNTESLTNVKDGDVAQYFPPGIEPSTVYPKIKCDGTNTNGAVVVNLGNLPLATAPGTPNTSYGFVRFRGRVK
>NC_019678.1|WP_157229431.1|4464168_4466925_-|DUF11-domain-containing-protein
MIFDAKKKGKINFFSSLFTTIFLLNFWAIPSQAEGSKELVFQGGDRPYIEWSNRETAKISRKTLLKVVVKNGETVNLGSSVHNSFDGRDIVFRGPIPSTTEQICDVKRLDQGGEGLIDKTAKETAGPLPNPDGYTPCQFTVDSTGIYEVEFHSPNPDGGDPPAKSTSEDFPTDNQQQMTVAAWDITVRDEDGNTKNGRVFTNYLAMNMGTVEKSLNSNFFIQTKDGFLYKTSMNGIDPFGFIFFANSRGFIDQTDNSTLYHSANAGQNNFSLDPFLGNVQVQRPDVEDTNTDITHLVFFNRPDAETLNQLNIPLVPAIPITPTNFKFTGGNGGSGNQTVVGVGGNFSFDSTSPGSYEIIIDTDKDNIFDPSKDTVLQNIVTVGSNVVRWDGQDGQGNNLPPRINNDPYDARIRLRTGEYHFPMLDVESNSNGFVIEMLNAPTAFPVGNRFTVYYNDENYTTSNGTDVDLSGSGASNPRNASIGVDSNGGAHKFSNNYGDFKGIDTWAYFPSEATSTNLIITDDKSANVRGTKSVRFLEDKDNSGTVTVGDTVEYTITYSNQSPDFQTDATNFIIQDTLPPQLTYNNSEIVSKTDGNNIILNSSYSGSGALSNSGTLRVNDEIIIKITATINNDNDGDSINNQANATFNTNDSSATSGTALTDADSAGATQDNPPTQGNPFKQIDDDSQNTGNDPSNTADDEPTIITVEKTVVTGSPKVLLVKRITAINGVNFDQFVDDPNSIEDNNSNWPDSDPSDTSSNDFLRGAVNGGLVVPGDELEYTIYFLSIGEKDASKLKICDVIPTYTTFIPTAFNGSTPTDGGLSTANLGIAIAFDSTNYPKNPTAYITNVADSDRGEFFSAGETPPIACSSSNNNGAVVVNIVNKDNVNQDIIPTANVDQTQTKPTNSYGFIRFKVKVN
>NC_019678.1|WP_044291972.1|4463563_4463821_+|MoaD/ThiS-family-protein
MPNSIKIAVKLFAAYQEAYNEPELILEFPENTPVSQVREHLIKEHPELEQWRDVTRFGINLNFVEPDTPLNDGDEVVLIPPVSGG
>NC_019678.1|WP_015119606.1|4463207_4463396_-|hypothetical-protein
MSEDKAKNQAEKNNPKEEAPELSPELLDRIKHPAAIDNTIRNQSPEELKGNPAVSPEMLDDR
>NC_019678.1|WP_044291013.1|4462131_4463064_-|histone-deacetylase
MHNPTFPLIYSDEFLEHLTGRGHPEKPERLSAVVSALKEAVFSQQIEWRSPTPITQNSPLDFLKEIHSPRYIRKVRDIAAEGGGFLDTDTYVSPRSYDVALLAVNAWLDGVDIVLETGKPAFVLARPPGHHAEIDYGMGFCLFSNAAISAFQALKKPEVNRVAILDWDVHHGNGTQAIVENNPQIAYCSLHQYPCYPGTGKSSERGINNNVLNLPMPPSSDISTYRAGFEKEVFPFLSNFQPDLLIVSAGYDGNADDPLAMINLQPQDYGIFTKHCLKVTSKILFGLEGGYDLPTLSQSVIATVEKCLNW
>NC_019678.1|WP_015119617.1|4489119_4491117_+|iron-uptake-porin
MKQNLLISASGVSLLCLLAGLSPLKALAVEKIGNRQAINSSENLLANKVLSQESFSSTNAIISEKVNNQFRFDVGSHSLGEYGILTTNETAASEKKENAIREARRLRRIPQLNKQLNKNATLIAQVAQTQQKTSAGQVTSVSQLSDVQPTDWAFQALQSLVERYGCIAGYPNGTYGGNRAMTRYEFAAGLNACLERVNELIATATTSIVAKQDLTTLQRLQSEFSAELATLRGRVDTLEARTAQIEASQFSTTTKLQGEAIFAAIGATGGAPDSDNPNIILTNRVRLNLNTSFTGKDLLITGLQAHNFGGDADGSGSLQQGLGLTAPGVNLAASSARTGIEPQFPGFTPKDLSSKDANSVELYKLLYIFPVANKLTLFAGTAAEVSDAFPTITPFAGEGQEAISRFAGLNPVLRVSGGTSGSGLASAAGFIFTPSKSFDIRALYASVNANIPSSEEDILPGVSGTPLGSGLFGGSTVAAAQLTFKPSNSLDIGLNYANSYHEINILGTGLVSTDTNALGLADGNLGIPVKLNSVGGTVNWRFSPNIALSGYGAAIFVDDSSSQVDASTTFTSWMVGLHFQDLIKKGNTAGILFGQPLYRTEADGDANLATDGVERQTPYHLEAYYKFKVNDNLSITPGAFVLFNPEGDDRNDTTTVGLLRTTFTF
>NC_019678.1|WP_015119618.1|4491196_4491544_-|hypothetical-protein
MNLNIVEQSLQIEFTLKEQFLAVRFKKIWEIPLSHIEQVTTTAPQTTWKELRSPGTALPGLVRAGTYYSQRGKEFWLVNYRKNNYLTIELQNENYKRIVMTVENNEFWQQRLNQK
>NC_019678.1|WP_015119619.1|4491821_4492316_+|DUF2996-domain-containing-protein
MAEETNKNEAASEDKPKAAAKPPAKAAGDKKPAAKKKEKPPAVEDKPFEEFMRQHYVPALTKAIADEGVEDLHLDFTKQKLPIPGYETAGECWQVLGSFGNGTRQFNVYFPDEDIKGKKAFSCNEGKSPSTLESFLIDERRITLDLMVFGVIMRLNGQKWLGRN
>NC_019678.1|WP_015119620.1|4492312_4492828_-|NINE-protein
MKVEAKDKHYDKEKERMKISYMLNVLGFLGFTGGLHRLYNGKVATGLLWMFTLGLFGLGQFVDLFLIPNMVEEREIKLRLKAGLSPFGVAQNPQAIASEIYQSPQETLMVELLKAAENRGGKLSVTQGVLDTGAKFSQVEATLQEMHKSGYVGIGNNPENGAVTYIFHELT
>NC_019678.1|WP_015119621.1|4493566_4494643_+|magnesium-protoporphyrin-IX-monomethyl-ester-(oxidative)-cyclase
MVDSLQKPGFEEIRPGVKAPAKETLLTPRFYTTDFDEMAKMDISVNEDELEAIIEEFRADYNRHHFVRDEEFEQSWEHIDGETRQLFVEFLERSCTAEFSGFLLYKELGRRLKGKNPVLAEGFNLMSRDEARHAGFLNKAMSDFNLSLDLGFLTKSRSYTFFKPKFIFYATYLSEKIGYWRYITIYRHLEKHPEDRIYPIFRFFENWCQDENRHGDFFDAVMRAQPQTLNDWKARLWCRFFLLSVFATMYLNDIQRHGFYGAIGLDAREYDKEVIEKTNDTAGRVFPVMLDVKNPEFYERLEICVNNNEKLREIVNSTKPKFVQIFQKLPYYISNGWQAVKLYFIKPIDAAAMEGSVK
>NC_019678.1|WP_015119622.1|4495268_4495703_+|hypothetical-protein
MLLRSLMTIFISCVIGIFSWVYAPAALATTPIPLSNISYQECPPELAEGNVTSGGASRAANCFIVTGVAKNMTSKTVYDADIFGRIYDANNNSVMQNRTRLGSISEVPPGETNFEMRITVPANQPTPLKLKQFKASGFTSKVRY
>NC_019678.1|WP_015119623.1|4495882_4496158_-|YggT-family-protein
MNLLIQTLLTFTQIYSFLLIGRVLLTWFPQIDWYNQPFAALSQVTDPYLNLFRNIIPPLGGIDLSPILAFLALNIISGLLANLAGPMASSF
>NC_019678.1|WP_015119624.1|4496364_4496727_-|hypothetical-protein
MSQRDGFASGFFAGAIFGSVVGGVIGTLVAQRRDAEELTEDEREQQASGKGNSNSNKSKRRQMQGSASSGVEMEIARRSLEDKIAQLNATIDEVRDQLGNVNQNSSGINEFSSRNEELQS
>NC_019678.1|WP_015119625.1|4496818_4497469_-|uracil-phosphoribosyltransferase
MTLQLRVYVPPHPLIKHWLAVARDAGTPSVLFRSAMTELGRWLTYEAAREWLPTLETTVQTPLEVCPATLINPEVPVAVVPILRAGLGLLEGAQTLLPLASIYHLGLVRNEETLQPECYLNKLPEKINPQTRVLITDPMLATGGSIMAAMSELTQRGVDPALTRIVCVVASPPALQQLSAAYPSLNIYAATIDEKLNEQGFIVPGLGDAGDRIFGT
>NC_019678.1|WP_015119626.1|4497884_4499372_+|carotene-isomerase
MHDVIVIGSGIGGLVTATQLVAKGAKVLVLEGYTIPGGSSGYFERQGYRFDVGASMIFGFGDKGTTNLLTRALQAVDVSLETIPDNVQIHYHLPNSLDLKVERNYEDFLQNLITSFPHESKGIRRFYDECWQVFNCLNQMELLSLEEPRYLMRAFFGHPLACLGLAKYLPQNVGDIARRYIKDPELLKFIDIECYCWSVVPADMTPMINAGMVFSDRHYGGVNYPKGGVGQIAQKLVEGLIKKGGEIRYQARVTQIIKEKGKAVGVKLANNQHYRAKRIVSNATRWNTFEKLLRAVEIPANEKKWQLRYKKSPSFFSLHMGVKAELLSPETECHHILVSEWEKMMDSEGTIFVSIPTLLDPELAPQGYHIIHAFVTNWIDEWEGLSQKEYEAKKEATANRILDKLEKIFPGINANLDYLEAGTPKTHRRFLGRVDGTYGPIPRKKLWGLLGMPFNRTAIEGLYVVGDSTFPGQGLNAVAFSGFACAHRVGVDLGL

Crispr_ID: NC_019678_21

• CRISPR_ID: NC_019678_21
• CRISPR_location: 4614575-4614973
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 7 spacers

Consensus repeat of NC_019678_21

Consensus_repeat	Method
AAGGTGGTAANGGTAANGANA	CRT

spacers of NC_019678_21

>21.1|4614596|33|NC_019678|CRT
CCTTAAATGGCGGTAATGGTGCCGACTTACTTC
>21.2|4614650|33|NC_019678|CRT
GCCTTGAAGGTGGTAACGGTAGAGATGTTTTAG
>21.3|4614704|33|NC_019678|CRT
CCTTAAATGGCGGCAATGGTGCTGACTTACTTC
>21.4|4614758|33|NC_019678|CRT
GCCTTGAAGGTGGTAACGGTAAAGACGTTCTAG
>21.5|4614812|33|NC_019678|CRT
CCTTAAATGGCGGCAATGGTGCTGACTTACTTC
>21.6|4614866|33|NC_019678|CRT
GCTTAAATGGTGGAAGAGGTAACGATACCCTTG
>21.7|4614920|33|NC_019678|CRT
TTCTCGAAGGTAGTCGGGGTAATGATGTCCTTG

CRISPR arrays and Neighbor proteins around NC_019678_21

CRISPR arrays

The CRISPR arrays of NC_019678_21

>merge|NC_019678|21|4614575-4614973|CRT
AAGGTGGTAACGGTAAAGACACCTTAAATGGCGGTAATGGTGCCGACTTACTTCAAGGTGGTAAAGGTAATGACAGCCTTGAAGGTGGTAACGGTAGAGATGTTTTAGAAGGTGGTAACGGTAAAGACACCTTAAATGGCGGCAATGGTGCTGACTTACTTCAAGGTGGTAACGGTAATGATAGCCTTGAAGGTGGTAACGGTAAAGACGTTCTAGAAGGTGGTAACGGTAAAGACACCTTAAATGGCGGCAATGGTGCTGACTTACTTCAAGGTGGTAACGGTAAAGACAGCTTAAATGGTGGAAGAGGTAACGATACCCTTGACGGTGGAAAAGGTAAGGATATTCTCGAAGGTAGTCGGGGTAATGATGTCCTTGATGGTGGAAAAGGTAATGATA

>NC_019678|21|6|4614575-4614973|CRT
AAGGTGGTAACGGTAAAGACA	CCTTAAATGGCGGTAATGGTGCCGACTTACTTC
AAGGTGGTAAAGGTAATGACA	GCCTTGAAGGTGGTAACGGTAGAGATGTTTTAG
AAGGTGGTAACGGTAAAGACA	CCTTAAATGGCGGCAATGGTGCTGACTTACTTC
AAGGTGGTAACGGTAATGATA	GCCTTGAAGGTGGTAACGGTAAAGACGTTCTAG
AAGGTGGTAACGGTAAAGACA	CCTTAAATGGCGGCAATGGTGCTGACTTACTTC
AAGGTGGTAACGGTAAAGACA	GCTTAAATGGTGGAAGAGGTAACGATACCCTTG
ACGGTGGAAAAGGTAAGGATA	TTCTCGAAGGTAGTCGGGGTAATGATGTCCTTG
ATGGTGGAAAAGGTAATGATA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015119704.1|4597279_4599184_+|EamA-family-transporter	unknown	unknown	gnl|CDD|223769
NC_019678.1|WP_052330829.1|4605989_4606325_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119719.1|4623545_4625753_-|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|270284
NC_019678.1|WP_015119721.1|4626967_4627681_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_044291993.1|4600989_4601604_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119712.1|4611630_4613955_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|369791
NC_019678.1|WP_015119709.1|4606863_4608969_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|315987
NC_019678.1|WP_015119711.1|4611044_4611530_+|glycine-rich-domain-containing-protein-like	unknown	unknown	gnl|CDD|369245
NC_019678.1|WP_015119716.1|4620844_4621534_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_019678.1|WP_015119715.1|4619402_4619879_+|outer-membrane-beta-barrel-protein	unknown	unknown	gnl|CDD|379226
NC_019678.1|WP_044291025.1|4628048_4628480_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119718.1|4622825_4623461_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119714.1|4617383_4618913_+|calcium-binding-protein	unknown	unknown	gnl|CDD|380205
NC_019678.1|WP_015119708.1|4602912_4605375_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119724.1|4629979_4631800_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NC_019678.1|WP_044291023.1|4609361_4610741_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NC_019678.1|WP_015119723.1|4628665_4629550_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015119705.1|4599709_4600609_+|heterocyst-differentiation-master-regulator-HetR	unknown	unknown	gnl|CDD|183916
NC_019678.1|WP_015119720.1|4626026_4626971_-|DUF1822-family-protein	unknown	unknown	gnl|CDD|370155
NC_019678.1|WP_015119707.1|4601902_4602511_+|30S-ribosomal-protein-S4	unknown	unknown	gnl|CDD|177038

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015119704.1|4597279_4599184_+|EamA-family-transporter	gnl|CDD|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	7.28846e-22
NC_019678.1|WP_015119720.1|4626026_4626971_-|DUF1822-family-protein	gnl|CDD|370155	pfam08852, DUF1822, Protein of unknown function (DUF1822). This family of proteins are functionally uncharacterized.	1.65419e-54
NC_019678.1|WP_015119716.1|4620844_4621534_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	4.71297e-15
NC_019678.1|WP_015119712.1|4611630_4613955_-|tetratricopeptide-repeat-protein	gnl|CDD|369791	pfam08281, Sigma70_r4_2, Sigma-70, region 4. Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.	6.27646e-05
NC_019678.1|WP_015119709.1|4606863_4608969_-|tetratricopeptide-repeat-protein	gnl|CDD|315987	pfam13424, TPR_12, Tetratricopeptide repeat.	1.41014e-11
NC_019678.1|WP_015119711.1|4611044_4611530_+|glycine-rich-domain-containing-protein-like	gnl|CDD|369245	pfam07173, GRDP-like, Glycine-rich domain-containing protein-like. This entry includes Arabidopsis Glycine-rich domain- containing protein 1 and 2 (GRDP1/2). They are involved in development and stress responses.	2.04074e-07
NC_019678.1|WP_015119719.1|4623545_4625753_-|CHAT-domain-containing-protein	gnl|CDD|270284	cd13566, PBP2_phosphate, Substrate binding domain of putative ABC-type phosphate transporter, a member of the type 2 periplasmic binding fold superfamily. This subfamily contains uncharacterized phosphate binding domains found in PstS proteins that serve as initial receptors in the ABC transport of phosphate in eubacteria and archaea. After binding the ligand, PstS interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The PstS proteins belong to the PBPII superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.47322e-53
NC_019678.1|WP_015119715.1|4619402_4619879_+|outer-membrane-beta-barrel-protein	gnl|CDD|379226	pfam13505, OMP_b-brl, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	0.000469218
NC_019678.1|WP_015119714.1|4617383_4618913_+|calcium-binding-protein	gnl|CDD|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	9.05329e-29
NC_019678.1|WP_015119724.1|4629979_4631800_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.16831e-177
NC_019678.1|WP_044291023.1|4609361_4610741_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	5.66691e-103
NC_019678.1|WP_015119705.1|4599709_4600609_+|heterocyst-differentiation-master-regulator-HetR	gnl|CDD|183916	PRK13245, hetR, heterocyst differentiation control protein; Reviewed.	0
NC_019678.1|WP_015119707.1|4601902_4602511_+|30S-ribosomal-protein-S4	gnl|CDD|177038	CHL00113, rps4, ribosomal protein S4; Reviewed.	1.34745e-124

Protein sequences

>NC_019678.1|WP_015119712.1|4611630_4613955_-|tetratricopeptide-repeat-protein
MFPSDFLTEMAHNQELSRDQEEVFLLRMGKGQSYEEIASELGTSADACLKRMGQVYKKFNVKGNSRGKENRLRIFLSNKWELLKAKALPEDNSQQLLINSQQTKVFDANSLENQISPILQNLPAREYATFVGRDREVARLMELLSYGHSAHLISVDGIGGVGKTTMVVEVAYRCLTASCNININLNSAGNLPVFEAIIFTSAKQNHLTCIGLLPRLIYQRTLRDICREIARIFEFTQINNLSLSEQIEIIHHKLSQTRTLLIVDNLETIEDKEGVLSFLYDLPPTVKVVITTREQTLFVPIRLNSLPQEHSLRLIQHESKEKGINLTSAQSQEIYEAVSGIPAAMIYAIGQMTAGYLFDDVLRLIKHPEGDIARFCFTASINPIKNSPPYYLLMALTLFVGSASRETLDNVTFEKPDPIVVSQGLVKLQQLSLICQQQARYSLAALTREYAWAELAANAEFAQHLRQRWVNWYLKFSESFGNLDWKEWNTNYENFEVEWENLQAVFEWCIANNRYSDVKTFWNFIKEYIFIRGYWDEHLEWSGWLIEAAKKENDYSTAVLAMCDRAVTLVRIRQIPQLREAQKILKESWELRHHQSASFELKLAANMAILHLHLGDLQQAQEWLEVKKQLLEKASLDKSEYKGQQVQILYYQGQIFYRQGDYQQAQIIFEEAVIKAEEIEWQKAIAAIDNWLADIALMNGDLAEARRLLEYSLPIAQRHKDKRIIAFHKSTFAKLEKTCGNKFQAHRLAKEAIDSFESLKMSAEAKEMYALLKT
>NC_019678.1|WP_015119711.1|4611044_4611530_+|glycine-rich-domain-containing-protein-like
MKIVAFFDRVNNLDFEMVAKRVVFKHGWTIERTQVAINRYKLFLYLKSVYPATGLVPTPEIDVVWHAHMEVNLIQYIQDCYYLFGYILNHCSAIYGEQNQATSLIHQQAFSTTKALFEEFFGFSILDNTSLHAAACADIPIDTNPAACADLPIIPNTIIGH
>NC_019678.1|WP_044291023.1|4609361_4610741_+|cytochrome-P450
MTSNYNLPPTVEMPIFLRRMKFIFQPFQYLEQNAQLYGDTFSLPQKDGSSTVYFGQPEALQQIFTADPKSLETGRGSRILRFLVGDNSVLLLHGDRHQRQRKLLTPPFHGDRMRAYGMTICEIAQQVSDEWQTEKPFNIRESMQEITLSVILRAVFGLDEGNRLQKIRLKISSLLDYLSSPLLSAGMFFPVLQKDWGSWSPWGRVLYLRQQIDDLIYDLIEQRRAESNPNREDILSLMMSARYEDGGEMSNQELRDELMTLLFAGHETTASALTWAFYWVDYLPEVREKLLKEINDLGENAEPNLVAKLPYLTAVCQETLRIYPIVPSATPRIASCSMEIGGYTLPKGTWIIPSIYLAHYREEVYSQPQQFKPERFLERQFSPYEFFPFGGGNRRCIGLAFAMHEMKLVLATILSQYEVSRIDKRPLKPVRRGLTLATPAGMKMVAKPIKKVANTPVAV
>NC_019678.1|WP_015119709.1|4606863_4608969_-|tetratricopeptide-repeat-protein
MKKLKKDNYSRFVIRDLARFSLTALLGIVLVGESVNAIPKSVGVEVAQQGVVDNKEPIRKQVLKLIQEGRQLSKQGNAESLKQAITKWEQALELLQQIGELKSSQAVLLYSIGNTYSNLGEKQKALNYYNQALPLAREIKDKFAEASILNNVAVIHDDLGDKHQAFKVYNQALLLSRKIDDKGGEATNLNNIGGIYNHLGDKQQALKFYKQALIIIQEINGDKRWEAGSLNNIGQIYDSLGDKQQALEYYKQALTISEEIADKNGQAITLNNIAAVYSSLGKKRQALTYYEKVLPLLETLGYRREKAIALHNIGSIHLDLGDKQQALKLLNQALLLSREVENQSGEAATLNAIGEIYNLLGDNQQALKFYNQALVLRRKVEDKSGEAVTLNNIGSVYSYSGENRKALEFFDRALILKRKVEDKSGEAKTLHNIATTYRDSNLQTALTNSKAAVDIIENLRTKVDSNELRTSYFATVQDIYKLHIDILMQLHKQNPSKGYDAQAIHASEKSRARGLLELLTEANANIRKGIKPELLAQEKNLQQLINSKEKSRLDKLSDKNVSKTDVQNLQQEVQNHINELNQLKAKIKTTSPKYAQLKYPQPLNLPKIQQQLDKDTVLLQYSLGEKRSYLWMVTPDSLDSYELPESEQIETAAKKLRNLLQDPSTQERSIKQTSEAAMELSNLILAPVADKLGKKTFDNRR
>NC_019678.1|WP_052330829.1|4605989_4606325_-|hypothetical-protein
MLKYPKKFRMIGYSKDFPTPETLKAFPYLKAGEGLTAGVHDGCSILKEEAGSLSHDCDTTGGSSGGPIVAQIKGKYYIIALNNAERFDMYGGAIDNRAVKVSFLNRLFGRR
>NC_019678.1|WP_015119708.1|4602912_4605375_-|hypothetical-protein
MATKINQFDDSNLQSQNSFSSVTNNALPQSPTNNLDISAATYLGGKEDDSTNAVDISLDGKFVIVGGSLKNANLGAEETELLGGGDGTIVRYDSQTNQAVATTRLPGKILDLEVSKNGDIAVAYEGGIAVLNADATEVKWSQSLSRVMRIAISDTGKVGVLQDSQGPDRAYLYDSNGERLKDWSTGKTRRQFADIAVTDQNGGMVITTGYEQKTNILQVAFTQAWSYEGEDVWKNYDFDNKDIYEENLMADTRGQRVAIGRDGQLYSSYYVNGGTGFSIFYRDPFDLSEKVTGDRKIETDKYNSPTNVGSVKMSWYGRYNLENGDLIKGQSLLGRRDDGKGNSVDISSITATEDGTVIIAGSAAGKIANRDKQTIEGQKVSDYVSYDGYIATISPDFQERLSWTPISDSGGGVVASFRNGTTAAVATTNFTGSQITHNAIQDSAGGKNDGYLIVIGGNDVPPGTEPATPTDNPTPVDDTPDTTGGNETPIEGKDILEVSTLESYGGSQDNPKNGTVELSSDNELNIKGNRWQKLEINSTITEKSILRFEFAGNGNGEIQGIGFDNDNVINTQDGKRFFQVDGSQSWGIENLSQFIVGKSGDKDIYEIPVGQFFTGDFEYLTIANDDDQKNPDAEGKFSNIRLFSDTPPTIQTPEETPEETPDSLNISINGQIETEEVLSYGGLGQNTSITSTIKNNSELRLEKNGWKRLDITGYEVTEDTVLKFEFAGNGEAEIQGIGFDNNNAISGNDGDNFFQVDGSQGWGIEDLDDYITGSNNGFTQYSIDVGDFFTGQFDSLTIANDHDVANPTAVGQFQNIELIG
>NC_019678.1|WP_015119707.1|4601902_4602511_+|30S-ribosomal-protein-S4
MSRYRGPRLRITRRLGELPGLSRKTARRAYPPGQHGQNRKKRSEYAIRLEEKQKLKFNYGLTEKQMVRYIRKARRVTGSTGQVLLQFLEMRLDNTIFRLGMAPTIPAARQLVNHGHVQVNGREVNIASYQCRPGDLIGVKNKEASRQLVETNLQYPGLANLPSHLEFDKNNLTGKVNGVCEREWVALSVNELLVVEYYSRKA
>NC_019678.1|WP_044291993.1|4600989_4601604_-|hypothetical-protein
MLSMQRFDFKLFKITAKLTLPALAITSILGITLPSNAISNPFRRNQNDYRVCAARLLSVGIPAETAGNACAAALRPKEVSSCVGQIQRRSQIPATDSLPFCGQARRPNDLATCVVGIGTRSAETVNPAILSYCNRSLLPVKFAQCVVGLRSEIDFSPTQAMENCISASDRISNVVPLSNPAVPAVPPVPPSEGFSPTFETTPMR
>NC_019678.1|WP_015119705.1|4599709_4600609_+|heterocyst-differentiation-master-regulator-HetR
MHNDTDLIKRLDPSAMDQIMLYLAFSAMRTSGHRHGAFLDAAATAAKCAIYMTYLEQGQNLRMTGHLHHLEPKRVKAIVEEVRQALTEGRLLKMLGSQEPRYLIQFPYVWMEKYPWQPGRSRIPGTSLTSEEKRQIEQKLPPNLPDAQLITSFEFLELIEFLHKRSQEDLPARHQMPLSEALAEHIKRRLLYSSTVTRVDSPWGMPFYALTRPYYATASDEERTYIMVEDTARFFRMMREWSERQRHTMRVLEEMDIPPERIDEALEDLDQIIRAWADKYHEVGGAPMALQMVFGKKED
>NC_019678.1|WP_015119704.1|4597279_4599184_+|EamA-family-transporter
MGRFDNGPEKPRRAGEPYGSAESALRAVTEELQIIQRNLLKSLQDDVKRLQSEKIRLADDIKRLQEEREQLQGGRQIDELQVLMRQLAQVLGNHISVQLQASLERLVNDRSTVSTTLQSGSGTYTQTQNQESELIGNSFNNAFNTLQQDLEDYQSSISQQLSRMSLQQEQGEAILVELVNRLKQELEATSIDNSPADFQVEEQDERLEDDYISEVDYVEDSPQIEEDEDTSQQEPFPSSLLEERDQIAPLQGDTTTATSTVRGANVSLPETSPQTVPEATRQPATPSQPISRQMEVFKQRPKGLLLIGLSAVATSIYNVAIKAIFNGIFDSDQLISPTLGNCLFVLMLRMLVVVPMMLVLAPILHPRVWHDLQNLIESIKASRNPASITARRVLMLSTISGGFLFLSQVMLYLSIGQIATGMAIALLFVYPIVSGILSWLLFRDIPSKFRAFAYAMIVLGIVLVLGGASDTNNLSFGSITGIFAGISFAFYVILTRICAARLHPVSFTLINFATMLFLCFISLCFITILLPLPSGWSLDINSTNFLELILSTFILGVLTLCGYLLNNFGIRKLGATRAGLISSTVPVLTVIFAGILIQESLPFIQVIGVLLVTFGAAAFSIEKIQQQIKASRSS
>NC_019678.1|WP_015119714.1|4617383_4618913_+|calcium-binding-protein
MLFYGTAKSEKLNGTHRADFIFGKGGNDTLKGRGGNDFLLGGRGNDSLKGGNGNDVLLGGKGNDTLEGGNGNDLLKGGKGNDLLKGGNGNDTLKGGKGNDTLEGGNGNDLLKGGKGDDLLKGGNGNDTLKGGQGDDTLNGGNGNDLLNGGIGNDLLKGNNGNDILLGSKGHDILDGGKGKDSADYSHLHQAITLEAFGVVHKGSLGTDQLLNIETIIGANGQANTIDGSTATSGVTSFDIDLSDERLTVENIPGLGDVTFTVKNFVNVVGTTQDDCIIGNSKDNILIGGGGNDYFGGSAGNDVINGDDSGYDTVDYTGLGEAITLLPTGIIEKDGGLGTDELIRVETIIGDENQANTIDTSSAESPISIDVDLAAETLEVNNIPVIGSLNRTVVNFVNVIGTAQDDKITGNAEDNIINGFGGIDNLTGGAGIDTFVLGEDYHVFYSDAGFGDVAIIEDFVSGEDKIQLTGSLDDYSFIQNSFTNLIAFGDDIIASVNSSFDTNSDFTFA
>NC_019678.1|WP_015119715.1|4619402_4619879_+|outer-membrane-beta-barrel-protein
MRQFFKSVAKISTASSIACAVTFASALSASAQSEQGLDGHYVGGSFQTGSGITSLGIYGRYDFPKLPVSVRGSIAVIDNDNDTETFFQPAVTYDLPIGDKANAYAGAGLAFGSGDSTAFLNAGAETEIATNVVAFGDLIIPLDDDADTGFGIGLGYRF
>NC_019678.1|WP_015119716.1|4620844_4621534_+|response-regulator-transcription-factor
MSLNLQTTKSPTILLIDSYEIFLNGTLEILSSFYPDAQIYTAITVEQALHQIALVKPDLVITDIYVARDIGDAIKINSGMQLIKELLRKCPDSNILVQSSYINSLVRIKAEIDKHPSGFVVADKSLSSQETLNRVRWTLQGWTHTKDIRAINSGLELKPEWLRLLNLAFEEGLQDKAIAAHICVSERMVRHYWFKLQEVLNINVDELKHQGKNLRVITHLRAREEGLID
>NC_019678.1|WP_015119718.1|4622825_4623461_+|hypothetical-protein
MNRSSVSLIMLGFGIVAYVLKLNAAIAFSPPQLLTAQAELVSLFSQLNTDNPVVAASGWKKFYSDEGNFSIFVPSTSVANLNSNSEEYSINIYYADTKKSSYIVGYVDYNTDLTNLPLDEVYHQFLKDFLGNQVNFINQKNIKLGQYSGIEVEYQSNNQKIAAKSRLFLVDQRLYILDISNYKAGDANQFFNSFKLEKNIKENPSEIAVNI
>NC_019678.1|WP_015119719.1|4623545_4625753_-|CHAT-domain-containing-protein
MAIVKLKIRESKEGFQVDLTARELYIEAEGYLPPLPPKLETSFNNWQLAYREIDAVRSVFTSTQVRLTPKNITKYSSAEYTTSVKDSLNQWLNCGDSKWLPVRDRLIAIAQQLHHKNEEIRVIIDAKDVKLRRLPWQEWNLFEEHYPQVEIALSAAKNTLKQTKYTIPQSSKIRVLVAVGRSDGINTQEDLEVIKDLEQHGAEVVCLMQPNRKELCEALWDEQGYHIFIFTGHSGSQENGHIGWIELNDTDRLSIEEFKEALKQAINKGLQLAIFNSCDGLGLASQLAHLHLSRCIVMREPVPDRVAVEFLKYFFKEFTRNQSLSTALNKARKQLEHFNLDYPGAVWLPTICIAPNVRSLTWKSLNPENVAPVEVSHKLEKPLPKDKPNIKVLIFICLFVSSIAGILAWNWFSKPQPIQPIAKIPTEKPFAQFASVNVPSAKFNYGGSTTWAPITKLLNKKINRVHPQFQLEYKRRQQEEPGSGTGIQMLLNKELDFSLSSRNLTTSELEDAKKLGINLQKIPIAVDAIAVAINHSINIDELTLKELEKIYTGRIRNWQELGGPNLAIKPYSRSKEVGGTVEFFYRNVLRGEKFSNSLEIVRDTTQGIRKVSQNPAGIYYGSASEIVNQCRVKTVKLGNTKDNMVAPYKQPLILPPDCEQKPNQVDIDKLSSNDEYPITRRLYVIYKHSSINPDPDLTEDFKIVKAAKAVEAYTKLLKTDEGKQLIKEAGFLPVN
>NC_019678.1|WP_015119720.1|4626026_4626971_-|DUF1822-family-protein
MNSAQPNYLQVSLGKDAHQKAEEFAAEQDSVEKGKQVYLNTLAVYAVNNYLKWLKVETALHQSDSWDWRIRTFFDVADLMLENVGKIECRPLLPGMDAVVLPQEVTKERIGYVGIRFSERLDFVEILGFAPARAIVGHSEVIAINKLQSFDVLIDIINQRKSLVNLCQWFEGIFDRGWQSPELVFAGDFRSSKLRHRYRSAATVTREDKDYVTNSISRAKVVDVGRQIILLIELTPTNSEVFDIRLRVYPAEDTVHLPSGLQLSIFDESGNACMQAQSEAADDWMQLEFGCQHEEKFSVELKLGKACITEEFVV
>NC_019678.1|WP_015119721.1|4626967_4627681_-|hypothetical-protein
MDEKLQQLIEEVCRYREGTPQRQKALNKLLIIVQQLPGIYKSYHQDYLEALNKTWDWFCRSIDKFEANPNKSLQESLVIWINGYLKWRVKDIYNPTDKPTVSLDELIINAEGQKTTRKDQLSDSKYTPDASNRSNTLDLLDVKIAEIQKSDRRKLAEDIAQLIEEDPKCELRHCYTRANAECNCQFLAKQLLLANPSHKIADIARDLNVSSQTIYSHWKRICLPLLQKIGVNLRIEK
>NC_019678.1|WP_044291025.1|4628048_4628480_-|hypothetical-protein
MMFASTQPEIPQPKWLHQLDKFVKAHQQELAALSWALWQQNGDSKGTIGIDLQPKPHFVYCPKEAIEKFNDNVDNKLQEILGLVENHKPEVEVLMIGIGKEQIKLVYFEPETPPPVCYRQVDKDLDGLMDVLEELLAEEIIVN
>NC_019678.1|WP_015119723.1|4628665_4629550_-|hypothetical-protein
MKNNSHPKPLGIILVFLLTFGSTVFAGFLASIFISKSYWGYYFNPPELPQKVEEFETIRSITPVSSIKRNNGNRIFKIDTSNSCIQDILSGIENLKSSCGTGKCNTEYCDNSRVVLSLANQQKLPEKTSYISPDKLNSLYKYLESTELLYEGEAGYNGELIADSATGDLISKGDGKRLEGVVVEAEDKKKQLYLFIAVNGGQISNDHYPYYEFLFELPKDKSTPKLIANNRFFYEIAGVEGILEWNVIWMFFIAIGFILSIPITILLISIKGRKKSQQLLLPGSSEQLTINSDR
>NC_019678.1|WP_015119724.1|4629979_4631800_-|ABC-transporter-ATP-binding-protein
MAQVLKSNRLQKQRQDSAHPLKRLLDYGHDYRQKIWLAVVCSILNRLFDLAPPVLIGFAVDVVVKQQDSIIASWGITDIFWQFLILSLLTVVIWVLESVFEYALETLWRNLAQTIQHDLRLDAYKHLQNLELAYFEERSTGGLMSILSDDINQLERFLDVGANDILQTATTIIILGGAFLILAPNVAWMTMLPIPFILWGTFAYQDLLEPRYADVREKLSFLNSRLSNNLGGITTIKSFTAEEYESKRLESESDAYRRSNSKAIKLSAAFVPLIRMLILIGFTALLLFGGMSAVNGNMSVGTYSVLVFLTQRLLWPLTRLGQTFDLYQRAMASTIRVLNLLDTPITINPGNIDLPVEKVRGEIKFNNITFAYKDRQPVIKNLSLEVPAGKTIAIVGSTGSGKSTLVKLLLRFYEVTAGNITVDNIDLQNINLQDLRRCIGLVSQDVFLFHGTVADNIAYGSFNANDKEIMNAAKVAEAHEFIMQLPQGYETIVGERGQKLSGGQRQRIAIARAILKNPPILILDEATSAVDNETEAAIARSLERITVDRTTIAIAHRLSTIRNSDCIYVVEYGEIVESGTHEELLEHKGIYASLWRVQSGLRTVSS

Crispr_ID: NC_019678_22

• CRISPR_ID: NC_019678_22
• CRISPR_location: 5162108-5162565
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 6 spacers
• Cas_protein_info: RT

Consensus repeat of NC_019678_22

Consensus_repeat	Method
GTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG	CRISPRCasFinder
GTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG	CRT
GTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG	PILER-CR

spacers of NC_019678_22

>22.1|5162144|35|NC_019678|CRISPRCasFinder,CRT
AGAAAGTGCCCGAAAGGAACTTTCTTAATGAGAAG
>22.2|5162215|38|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AATTATGCGTCACTTTAGATCCTTTGCGTTTTGGAATA
>22.3|5162289|34|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TGCCCCAAAAGGTCACGATAACATCAGGGTGATA
>22.4|5162359|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR
GTCTTAGAACTTACTCTCTAAAGGATAAGCCGA
>22.5|5162428|32|NC_019678|CRISPRCasFinder,CRT,PILER-CR
CATCAGGGTGATACGACTAGAGGAACAGCAGA
>22.6|5162496|34|NC_019678|CRISPRCasFinder,CRT,PILER-CR
GCCTTCTGCTACTGAAAAAGCAGTGACAGCAGCT

CRISPR arrays and Neighbor proteins around NC_019678_22

CRISPR arrays

The CRISPR arrays of NC_019678_22

>merge|NC_019678|22|5162108-5162565|CRISPRCasFinder,CRT,PILER-CR
GCACCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAGAGAAAGTGCCCGAAAGGAACTTTCTTAATGAGAAGGTTTCCATCCCCGCTGAGGGGAGCTGGTTTGGAAAGAATTATGCGTCACTTTAGATCCTTTGCGTTTTGGAATAGTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAGTGCCCCAAAAGGTCACGATAACATCAGGGTGATAGTTTCCATCCCCGCTGAGGTGAGTTGGTTTGGAAAGGTCTTAGAACTTACTCTCTAAAGGATAAGCCGAGTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAGCATCAGGGTGATACGACTAGAGGAACAGCAGAGTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAGGCCTTCTGCTACTGAAAAAGCAGTGACAGCAGCTGTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG

>NC_019678|22|19|5162108-5162565|CRISPRCasFinder
GCACCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG	AGAAAGTGCCCGAAAGGAACTTTCTTAATGAGAAG
GTTTCCATCCCCGCTGAGGGGAGCTGGTTTGGAAAG	AATTATGCGTCACTTTAGATCCTTTGCGTTTTGGAATA
GTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG	TGCCCCAAAAGGTCACGATAACATCAGGGTGATA
GTTTCCATCCCCGCTGAGGTGAGTTGGTTTGGAAAG	GTCTTAGAACTTACTCTCTAAAGGATAAGCCGA
GTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG	CATCAGGGTGATACGACTAGAGGAACAGCAGA
GTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG	GCCTTCTGCTACTGAAAAAGCAGTGACAGCAGCT
GTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG

>NC_019678|22|7|5162108-5162565|CRT
GCACCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG	AGAAAGTGCCCGAAAGGAACTTTCTTAATGAGAAG
GTTTCCATCCCCGCTGAGGGGAGCTGGTTTGGAAAG	AATTATGCGTCACTTTAGATCCTTTGCGTTTTGGAATA
GTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG	TGCCCCAAAAGGTCACGATAACATCAGGGTGATA
GTTTCCATCCCCGCTGAGGTGAGTTGGTTTGGAAAG	GTCTTAGAACTTACTCTCTAAAGGATAAGCCGA
GTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG	CATCAGGGTGATACGACTAGAGGAACAGCAGA
GTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG	GCCTTCTGCTACTGAAAAAGCAGTGACAGCAGCT
GTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG

>NC_019678|22|7|5162179-5162565|PILER-CR
GTTTCCATCCCCGCTGAGGGGAGCTGGTTTGGAAAG	AATTATGCGTCACTTTAGATCCTTTGCGTTTTGGAATA
GTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG	TGCCCCAAAAGGTCACGATAACATCAGGGTGATA
GTTTCCATCCCCGCTGAGGTGAGTTGGTTTGGAAAG	GTCTTAGAACTTACTCTCTAAAGGATAAGCCGA
GTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG	CATCAGGGTGATACGACTAGAGGAACAGCAGA
GTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG	GCCTTCTGCTACTGAAAAAGCAGTGACAGCAGCT
GTTTCCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015120109.1|5153008_5153302_-|acylphosphatase	unknown	unknown	gnl|CDD|237713
NC_019678.1|WP_015120112.1|5155647_5158536_+|isoleucine--tRNA-ligase	unknown	unknown	gnl|CDD|215452
NC_019678.1|WP_015120120.1|5175820_5176678_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120104.1|5146280_5147486_-|serine-protease	unknown	unknown	gnl|CDD|379142
NC_019678.1|WP_015120108.1|5151573_5152842_+|hypothetical-protein	unknown	unknown	gnl|CDD|235046
NC_019678.1|WP_157229438.1|5149597_5150383_-|trypsin-like-serine-protease	unknown	unknown	gnl|CDD|379142
NC_019678.1|WP_015120105.1|5147595_5149554_-|serine-protease	unknown	unknown	gnl|CDD|379142
NC_019678.1|WP_015120121.1|5176844_5177792_-|glycosyltransferase	unknown	unknown	gnl|CDD|133055
NC_019678.1|WP_015120123.1|5179131_5180145_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120107.1|5150640_5151192_-|hypothetical-protein	unknown	unknown	gnl|CDD|372967
NC_019678.1|WP_015120117.1|5169616_5170582_+|NTF2-domain-containing-protein	unknown	unknown	gnl|CDD|370323
NC_019678.1|WP_015120122.1|5178058_5178979_-|polysaccharide-pyruvyl-transferase-family-protein	unknown	unknown	gnl|CDD|377253
NC_019678.1|WP_015120114.1|5163534_5165820_+|catalase/peroxidase-HPI	unknown	unknown	gnl|CDD|237891
NC_019678.1|WP_015120118.1|5170775_5173397_-|cell-division-protein-FtsK	unknown	unknown	gnl|CDD|224588
NC_019678.1|WP_015120111.1|5154027_5155209_+|gluconolactonase	unknown	unknown	gnl|CDD|308585
NC_019678.1|WP_015120110.1|5153575_5153944_+|DUF1823-family-protein	unknown	unknown	gnl|CDD|370156
NC_019678.1|WP_015120116.1|5167988_5168873_-|ParA-family-protein	unknown	unknown	gnl|CDD|224113
NC_019678.1|WP_015120119.1|5173666_5175754_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379062
NC_019678.1|WP_015120124.1|5180613_5181837_+|glycosyltransferase	unknown	unknown	gnl|CDD|274425
NC_019678.1|WP_015120113.1|5159727_5161521_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019678.1|WP_015120113.1|5159727_5161521_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	4.7e-50	164.9	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015120109.1|5153008_5153302_-|acylphosphatase	gnl|CDD|237713	PRK14423, PRK14423, acylphosphatase; Provisional.	6.57845e-48
NC_019678.1|WP_015120112.1|5155647_5158536_+|isoleucine--tRNA-ligase	gnl|CDD|215452	PLN02843, PLN02843, isoleucyl-tRNA synthetase.	0
NC_019678.1|WP_015120104.1|5146280_5147486_-|serine-protease	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	1.57724e-27
NC_019678.1|WP_015120108.1|5151573_5152842_+|hypothetical-protein	gnl|CDD|235046	PRK02507, PRK02507, proton extrusion protein PcxA; Provisional.	8.66893e-176
NC_019678.1|WP_157229438.1|5149597_5150383_-|trypsin-like-serine-protease	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	9.4622e-22
NC_019678.1|WP_015120105.1|5147595_5149554_-|serine-protease	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	2.08614e-24
NC_019678.1|WP_015120121.1|5176844_5177792_-|glycosyltransferase	gnl|CDD|133055	cd06433, GT_2_WfgS_like, WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	8.77831e-34
NC_019678.1|WP_015120107.1|5150640_5151192_-|hypothetical-protein	gnl|CDD|372967	pfam14218, COP23, Circadian oscillating protein COP23. This family includes the circadian oscillating protein COP23 from Cyanothece sp. (strain PCC 8801). The levels of this peripheral membrane protein display a circadian oscillation.	8.21797e-50
NC_019678.1|WP_015120117.1|5169616_5170582_+|NTF2-domain-containing-protein	gnl|CDD|370323	pfam09150, Carot_N, Orange carotenoid protein, N-terminal. Members of this family adopt an alpha-helical structure consisting of two four-helix bundles. They are predominantly found in prokaryotic orange carotenoid protein, and carotenoid binding proteins.	7.69522e-95
NC_019678.1|WP_015120122.1|5178058_5178979_-|polysaccharide-pyruvyl-transferase-family-protein	gnl|CDD|377253	pfam04230, PS_pyruv_trans, Polysaccharide pyruvyl transferase. Pyruvyl-transferases involved in peptidoglycan-associated polymer biosynthesis. CsaB in Bacillus anthracis is necessary for the non-covalent anchoring of proteins containing an SLH (S-layer homology) domain to peptidoglycan-associated pyruvylated polysaccharides. WcaK and AmsJ are involved in the biosynthesis of colanic acid in Escherichia coli and of amylovoran in Erwinia amylovora.	1.32303e-07
NC_019678.1|WP_015120114.1|5163534_5165820_+|catalase/peroxidase-HPI	gnl|CDD|237891	PRK15061, PRK15061, catalase/peroxidase.	0
NC_019678.1|WP_015120118.1|5170775_5173397_-|cell-division-protein-FtsK	gnl|CDD|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	1.03629e-57
NC_019678.1|WP_015120111.1|5154027_5155209_+|gluconolactonase	gnl|CDD|308585	pfam03022, MRJP, Major royal jelly protein. Royal jelly is the food of queen bee larvae, and is responsible for the high reproductive ability of the queen. Major royal jelly proteins make up around 90% of larval jelly proteins. This family also the sequence-related yellow protein of drosophila which controls pigmentation of the adult cuticle and larval mouth parts.	8.0011e-34
NC_019678.1|WP_015120110.1|5153575_5153944_+|DUF1823-family-protein	gnl|CDD|370156	pfam08853, DUF1823, Domain of unknown function (DUF1823). This presumed domain is functionally uncharacterized.	3.30911e-78
NC_019678.1|WP_015120116.1|5167988_5168873_-|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	4.70696e-53
NC_019678.1|WP_015120119.1|5173666_5175754_-|AAA-family-ATPase	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	1.14905e-05
NC_019678.1|WP_015120124.1|5180613_5181837_+|glycosyltransferase	gnl|CDD|274425	TIGR03087, stp1, sugar transferase, PEP-CTERM/EpsH1 system associated. Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.	2.83409e-60
NC_019678.1|WP_015120113.1|5159727_5161521_-|group-II-intron-reverse-transcriptase/maturase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	4.85368e-123

Protein sequences

>NC_019678.1|WP_015120113.1|5159727_5161521_-|group-II-intron-reverse-transcriptase/maturase
MVQSTIVNVTERATDWNSIKWKHANRVVTRLRQRIFKATRDGDLKKIRSLQKLLMRSYSNIVLSVRRVTQLNSGKKTAGVDKLLVLTPGARGTLVDILTRCPPWKPLPVKRVYIRKSNGKQRPLGIPCVIDRCLQAIVKNALEPYWEAQFERTSYGFRPGRGVHDAIERIHSMSKANSTKSWVVDADIEGCFDNIAHSPLLKTIGNFPAKKLIQQWLKAGYVDKGVFNDTETGVPQGGIISPLLANIALHGMESALGIRYDKHGHTIGNRGIVRYADDLVVFCKTQEDAACVVETLSHWMKSKGLALSKAKTNIVHLSEGFNFLSFNIRWYKDKNTKIGRKVLIKPSKEALQDVRNKIKQVWLENKSSNVNYLISKLNPIIRGVANYYRTVVSSHIFHKLDTWMYVRENRYAKRVHPKKSSGWRKHKYWGRLNFDRNDNWVFGEPVAVDGFPGISKLVNPEGDKRTGQYLLKFSWFNIRRHTLVKGDASYDNPDLVKYWESRTKRKSQNLIPSYQKLARKQGYKCCVCGESLFNDEPIQKHHKVPQSRGGKDTYANLELMHYYCHRQVHSVAPGCEDEVFVQDLQELNPVPGSVRIG
>NC_019678.1|WP_015120112.1|5155647_5158536_+|isoleucine--tRNA-ligase
MTESGSYKKTVNLPKTKFDMRANATKREPEIQKFWAENKVYERLSQENPGELFILHDGPPYANGSLHIGHALNKILKDIINRYKILQGRKISYVPGWDCHGLPIELKVLQTMKSSERQELTPLKLRNKAKDFAWEAVNEQRESFKRYGVWGDWEHPYLTSNPQYEAEQIAVFGDMFLKGYIYRGLKPVHWSPSSKTALAEAELEYPEGHTSPSIYAAFPMTNLADAAKDKLSEFLPDLGVAIWTTTPWTIPGNLAVAVNPDLNYAVVEVENLSAVDFKYLIVAADLAERLSETFGAKLTVKATFKGKELENSTYRHPLFDRESPVIIGGDYITTESGTGLVHTAPGHGQEDYIVGQKYNLPILAPVDANGKFTEEAGKFVGLKVVGAKDQISEGNQAIIDALTEAKSLIKHEPYAHKYPYDWRTKKPTIFRATEQWFASVEKFRETALEQIKSVQWIPAQGQNRITPMVADRNDWCISRQRSWGVPIPVFYDEETNEVVLNEDTIKHVQAIIAEKGSDAWWELSVEDLMPEKYRNDGRKYRKGMDTMDVWFDSGSSWASVVEQRPELRYPADVYLEGSDQHRGWFQSSLLTSVAVNGVAPYKTVLTHGYTLDEKGFKQSKSLGNVIDPRVVIEGGKNQKQEPAYGADVLRLWVSSVDYTNDVGIGKNTLKQIMDIRNKIRNTTRFLLGNLHDFNPETDAVAFEELAEIDKYMLHRMTEVFTEITNAYETFQFSRFFQAVQNFCIVDLSNFYLDVGKDRLYISSENGSRRRSCQTVMQIALENLTKAIAPVLAHMAEDIWQFIPYETPQKSVFEAGWVQLEDKWKNPDIVKFWDKIRQIRNDVNKVLEEARIDKMIGSSLEAKVLLYVKDEELRNAIKSLNDNSNNNVDELRYLFLTSQAEILDNPGVDDCKHKMQSDNWEIGVAKADGHKCDRCWNYSTKVGESTEHPLLCERCVNALAGEF
>NC_019678.1|WP_015120111.1|5154027_5155209_+|gluconolactonase
MRFSKLLLSSIAVCITVGLVLINNPVNAQRNLPQEKTVGNIETVATFNDAMPTGVTVSQTGRVFVNFPRWGDKVDFTVAEVKNNRSIPYPNAEINVANKDKPKDSLLSVQSVVIDALDRLWILDTGSIEFAPTINGGAKLVGVDLKTNKIFKKIVFPEDVALKTTYLNDVRFDLRRGKEGMAFITDSSLTGANAIIIVDLATGKSWRRLNNHPSTKAEDIDKFLPIVEGQPLMSRPPNAEPSPFKVGADGIAISSDGGRLYYCPLSGRTLYSVNVDALVQPASEEQVAKTVINHGDKGGASDGLESDAQNRIYVTNYEDNAILRRLPNGMYETVVHDSRLLWPDTLSLATNGYLYFTANQLHRQPNFHNGKDLRQKPYSIFRTKVDAKPVLLK
>NC_019678.1|WP_015120110.1|5153575_5153944_+|DUF1823-family-protein
MELPPLTTDTIWAILNKEIDDTTVNQLVWHYLGYGYDESTGKWDANNASEEWRSEYPEPPDFIANRPPTVKLTRSIPKENKQMLKEFLGFTGYKIGEFGPRETRRATAANWLLSYMKINGYC
>NC_019678.1|WP_015120109.1|5153008_5153302_-|acylphosphatase
MSNPTLPKQTRAHVFISGKVQGVGYRYSTMNAARNLGLNGWVKNLPDSRVEAVFEGASETVEKMIRWCHQGSDAAVVKDVQVEYSQLEGLQGFEIVS
>NC_019678.1|WP_015120108.1|5151573_5152842_+|hypothetical-protein
MYKSKKSLFQAIQQSWRFINKWFLDTPQRALLLAYEAALKIRDIEDKHFSGNKISEESNIYTANVLSYWQAELEKYLKTINFRLAEFQRSSSLLTVTDKTFLDKLKFIDEVTARYAVDKEFTTKRRIVTTQSNTQEQKEHYELDYDDTDINKMKVKPVTVKTGLFPGSITRSFKKIIKELSPRAEEKTVRDFRTSSKRTRIALKFLATLIIVPFLTYLFLKQLVIYPIVERVRTDAATDAFLNSHIEEQVLQEFKFYQQELKFEKLILQAPLLSSEIQQKQKERAIKIAEEFHHKNNSAISNVFADIISLIVFAFIIATSKREVAILQLFIDDTVYGLSDSAKAFLIILLTDMFVGFHSPHGWEVLLEGIAKHLGITPTRDVIFLFIATFPVILDTICKYWIFRYLSRISPSALATFKEMNE
>NC_019678.1|WP_015120107.1|5150640_5151192_-|hypothetical-protein
MKLGLLVRVLSGAAISSLTVFTAVTFSNQPSYAGGATFYCGTSTYRNKSVPTTFARTQDGKKVPIVRWISNYFPPPWTPKKRCGAVSNKFQRFYDHGILRYITADTLKGQPVLCATPSPGIGCTSDTVLFTLKPGSNPQATIRRLLDRRGLAGGMVLNESANSVDVDFEMYLQSGSNEARKRK
>NC_019678.1|WP_157229438.1|5149597_5150383_-|trypsin-like-serine-protease
MHFWHRWKFIGCFSCLSLVLSVSNLCCTLSAGSTNAVCENQSQAKQSSILSAKQLRHRAEQISVNVMAPSIVGTGFLLKKQGCVYTVVTNAHVLRAGKPPYRIKTSDNRIWEAQTRYVASEKGDDLAILEFRTRGESYPVAPIGVKPIPGTAVVAAGFPFVEGDTRVKFRLTAGKVSLVLDKALQGGYQIGYTNDIQKGMSGGALLNLRGEVVGVNGMHAFPLWDIPSVFESGEEADKALHEKIVRLSWAVPMQKVERLNR
>NC_019678.1|WP_015120105.1|5147595_5149554_-|serine-protease
MKLIYALSPVMLTVSTILVQPQFALAQSSADVAKIAKKITVLIDNQDSPGSGVIIQRSGNTYTVLTAAHVVRKTSDYNIVTSDGQRYKLNKSNIKPLQGVDLAVVQFDSNQQYATAKLGNSSNSTEGTTAYVAGFPKPTAAVSNSLYTFMDGRIIANASQSLRDGYSLVYSIDTLPGMSGGPILNQKGELIGVHGRGDTTENFNISDVNPNIIIKTGRNLGIPISTFTKQFKTAGLDTPKVAAAPNNAATNKPLADDFYLQSVEKRNKADFQGAIKDLNQAIKINPKYAFAYYRRAEARQNTGEREKAIKDLQKAAELFSEQGNKSDAFRSQGSMRMLKQDYPGAIAAFSQAIKLNPKDTDAYNERGMTRVQSGDLKGALADYNKSLSLQPSDAYAYMGRSFTHLKLQDKISAIADVNQAISIAPNYALPYLILGVIHYNFGDTPKAITTFNKASQLLAAQGNQSYAHGSQALAFQLSNNYPAAINSFTKAIKANPQDAEMYELRGDVYSRNGNIKKALADYAQAIRINPNDASAYTSRASIRLVQQKDSQGALTDLNKALSLDPSQDKAYFFRTIIRIQQKDRQRALADINNAIRYVVSDADKYMYKGIKSALQGNKPEAKNNLQRSANLYQLRGDKASYNEVMKLISMIN
>NC_019678.1|WP_015120104.1|5146280_5147486_-|serine-protease
MRYNHLLLPLLIGTSTTLIQPQSATAQSSPQVAKIAKEITVLINSDNSSGSGVIINKLGNNYTVLTAAHVVGRQDKYEIITNDNQRHAISSVKKLPNVDLAVVNFTNNNNNNYTSAKIGNSDTSTEGTTVYVAGFPKPTAAISESIYTFLDGRISANASKPLREGYALVYTIDTLPGMSGGPVLNQRGELIGIHGRGDTTQNYQISEANPNIIIKTGFNLGVPINTFKQLYAFKDTKPSIKKPPTTVAKKPKADDFYLRGGSKFKNKNYQAAVTDLSKAVNLNPRYEDAHMKLGDAFYKLKSYQKAKASYDKVLRLNPRNSIAYIKRGMTRNILKDYRGSVRDFNASLRIDRRSNYAAVAYLGRAVTYIRLGNKQKAQADLQQAKYVLNLNKKRRNSKTKR
>NC_019678.1|WP_015120114.1|5163534_5165820_+|catalase/peroxidase-HPI
MNNNPQSAPAQCPFRGTRVGGALGSKPQTDDWWPNRLQVELLHQNSPLANPLGDFDYKQAFQKIDFQQLKKDIKTLLTDSKDWWPADYGNYGPQMIRMAWHAAGTYRIADGRGGASRGMQRFAPINSWWDNGNTDKSRRLLWPIKQKYGAALSWADLMILVGNCSLEIMGLKTFGYGGGRIDAWEADRATYWGPEFWNGEAFGENGKEHEGHPNEMVTRTIRWEGEPKDEYYDLENPLGASHQALIYVDPEGPDGSGDPLASARDIRETFARMAMNDEETVALIAGGHAFGKSHGMVAADKIGPAPEGAPIQAMGLGWQNPEGTGFAEYTMTNGIEGSWTPNPTQWDNSYLENLFKYDWEKTKSPTGAIQWKPVDPGAPKTPDAHKTGVEHALMMMTSDVALKEDSAYHQVCQRFLGDFEYFSDTFARAWYKLTHRDMGPKVRYLGPEVPEEDLTWQDPIPQLDHDVVNDADISSLKNKILASGLSVSALVSAAWASASNYRDSDKRGGANGARVRLDPQKDWEVNRPQELSQVLSTLERIQAEFNGNQSGNKKVSMADLIVLGGCAAVEKAAKDAGIDTSVPFTPGRMDTTLEVTDVESFEWLKPVSDGFRNYHNEAVGYKVKAERIFLDRAQLLTLTAPEWTVLVGGLRALDQNWDNSKHGIFTDRPGVLTNDFFRVLTSMEYEWKPIDNREMLFNICDRNTGETKFTATRCDLIFGSNAELRQVAEVYGADDGHERMIKDFVAAWNKVMMLDRFDVSA
>NC_019678.1|WP_015120116.1|5167988_5168873_-|ParA-family-protein
MGYVISTANMKGGVGKTTLTVNLATCLAKNHGKRVLVLDLDTQISATLSLMSPIEFAKLRKKRRTLRYLIDDIVKSSDKAKLSIQEIIQPSVNNLSGLDLLPGDIDLYDEFVVSQMLHQQAVNLSENDFEVIWNRFERVLLGKILEPVRNDYDFILLDCAPGYNLLTRSALATSNFYVLPAKPEPLSVVGIQLLERRIAQLKESHEHEANIDISMLGIVFTMSNSNMLTGRYYKQVINRVYQDYGAEKICQTQIPVDVNVAKAVDSFMPVVLNSPQSGGSKAFNQLTQELLNKL
>NC_019678.1|WP_015120117.1|5169616_5170582_+|NTF2-domain-containing-protein
MALTIDSAQNIFAGTQVPSPIPATIALFDQLSVDDKLAYLWYAYTEMGKTITPAAPGAARLQLAESLLKQIKEMSAEEQTRVMRDLANRSDSPISRSYGFFSVNTKLAFWFELGELMKQGVVAPIPANYQMSEGVKVVLEATKKLDAGQQITVLRNTVVDMGFDTSGMAPSSSKAPAEPMFERSGETVSDVKIEGVNEPAVTKYIEAMNADNFDAAVSLFADDGALQPPFHKPIVGKQAIGKYMREEAQGLNMMPKKGISESRPDGSKQLKITGVVETPWFGANVGMNIAWRFLVNPQGKIFFVAIDMLASPQELLNLGRK
>NC_019678.1|WP_015120118.1|5170775_5173397_-|cell-division-protein-FtsK
MHYLTDTAQIRATINQFRSSKILWLDTEVADCRTPNPRLSLIQVLANPDDSTGEFAYILDVLDKPDLARYFIDQIMVNPQIEKVFHNASFDLKYLGGKLIPNVTCTLKIARKITRYKLKTSNLKLKTLATELCQFTDVDTESGASDWGKRPLIGKQLYYAAMDVVYLAAVHRQLISFNSVDKNSILKMAANKNKLTVTKVRIAFECPRLFYINDKFGGKTLFLPKDTATGIGSVFHSFADEFVRFTLREPRFKELFKAEASQLDIEEVAVEMQQLFYKAKFYPYLQQVTKTDKSRATPLLLVWQGLQNVIKRFAQILIVNRGYCSGSSVIRKTFVSEARQLEHFFDLPNKTRQLIRGEYDCLTYNFERQRLCLLEFKTYQSIDPSAQLAQVSLYGYMLFQQKQVPVDSAVYCVLPEFKEYYYGWEELENTVNQLIPYKLQQMQEWLSWKPSQPNCPPSTTQPYLCEICPQQEKCQSYFGDSIEIPPTPLNEAGLKDEEDLDRENKKYIVPDIQIPSTPPEKEKLKEENSVNADATAEELVTTLQSFGINVDFVGAAVAPSFIRVKLKPQLGVKFNSIQKLYADLQIQMGLENPPLIAPQAGYVSVDLPNPNRKAAFFDDYLKPQKSQITASVKIAIGVNLEGKLVEADLSDPNTCHFLVGGTTGSGKSEFLRSQLLSLLIRYSPQQLKIALVDPKRVTFPEFEKMPWLYSSVVKDSEKAIDLMDKLVSEMEFRYQQFEKTECADLGSYNQRSDQPLARIVCIFDEYADFMAEKESRNALEQSIKRLGAMARAAGIHLIIATQRPEAKVVTPIIRSNLPGRVALRTASEADSTIVLGGKKTAAAYLLGKGDLLYQVGAKLHRLQSLYAKKIKLP
>NC_019678.1|WP_015120119.1|5173666_5175754_-|AAA-family-ATPase
MTPINNIIKRELNPFDLINLKPGNFWGEKQDSDNSVDSIHQEVITEIEGLLDSVNQDNRSRSVLLLGDSGSGKSYLLGRLKRTLNKKAFFAYIGPWADSDYIWRHVLRSTVDSLIQIPEGREESQLILWLKSLSAFTRRNLKQRLFSDSIWQFMQSDRRKFIHHLKTTYSQAGLYNPDFFFGVLHDLTDPELYPIACEWLRGDDLSEESMQILKVKSCIDTEDAAKNILANFGRISIQTQPIVLCFDNLDNIPRLSDESQDFQSLFNVNTTIHNNYLKNFLVVVSIITNTWKLNSDRIQQADKVRIDKELRLKRINLEQAEALWAYRLKPLHHQVKPQPISPIFPLNRKLLQQSFPSGKTLPREVLVIGQKEYKKYKFSLVDSTVVKPIPEPEVITVPEEIKLPVPQPQIQAETIDAEFQLLWQKEYKKTQGKNQKITLFSAPDLIRMLEEALQALEVPDIKTKLLRGKYTSYSLSYRKSKKGNQIGIVWTEDSGMASFYNVMSASQKVIQSKGCETLYLIRSGSVGTSKLKGYQLYQKIFHSSKSSKHIHLKPSLASVHQLATYHNLVNSAVAQELVLSGRVIKLDELQELIRNSLIFEKCTLLQDLKVVPEPDDSEDGEDVIDLTPVNDFLFNLVKTQGFMGVPTLISQCMTQFSDAREDDVKMLIQDLCQEEKVKIIDPKAKSEDQLICLIA
>NC_019678.1|WP_015120120.1|5175820_5176678_-|hypothetical-protein
MDTNELKFLLKLLGCENYRSTLSGNAFKSFKGKNTICQNLGDREIIDFSREVAAVKILPPGQALLKLDAAEVPIEEKELRILENVAKVSGKVAPSKIKSSLKAAQKEEILRSLSDRGLIEAEIKLKKKKAEVWLTQRGIEFLRDDFSPKKGANPAISLDLLNNYLRFLRKSLKSQSQEATVTAPINNSEPVTQKSKAINDEEILQIIQKLDNELGTKDYLPIFYLREKLQPSMSRNELDQVLFKLQADDKIELSTLQEASAYTPEQIESGIKQNVGGPLFFISIF
>NC_019678.1|WP_015120121.1|5176844_5177792_-|glycosyltransferase
MPKVSICIPTFNRIDLLPFAIDSVLKQTYQDFELIVCDDGSSDGTADLMSKYEDSRIKYIRHRQNIGKSNNMLSGFDAATGDYFIKFDDDDRLTPNFIAETAAILDRDSNIDFVGTDHWIIDIDNVRDQTQTEENSRQWGREDLPGGVVNNLLQAVFVNQSFQIGATLFRRQTVVEVGFMQPNWQNCEDNDLFVRLALAGKKGYYLPKLLMEYRVHAEQQGINRAIPYLTGKQQYLQSYKFDSQELENIRLNRLRETQLLLGLRLIESGETEKGRELVNKGKSFSTAKAWTGLGLSLLPVGVRGKAFDALRKVKG
>NC_019678.1|WP_015120122.1|5178058_5178979_-|polysaccharide-pyruvyl-transferase-family-protein
MKLFYFSFPNGMSNFGDDLNPWLWEKLLPGVFDQDNKSIFVGIGTLLNDYVPKANKTAVFASGVGYSKGLPAIDESWKIYCVRGPLSAKKLGIDPQLAVTDGALLIRKVYEPSSIKKTKFAYMPHITHIIHGGNAWKDICEEAGISYIDPRWSTEEVLSAICETEVLLTEAMHGAIIADALRVPWIPVLTSTRIFPWKWQDWCLTVGVDYKPQYLMPWENVYSPGHGTVSSLRFKKNYACQAPIRLFKTLLQKESQKMANQLADIAKTSKPNLSSDTRIQQLTLQLEERLQQFQEDLTAGCFAVSN
>NC_019678.1|WP_015120123.1|5179131_5180145_-|hypothetical-protein
MQRFGIYTLANDIVYDQLVALLNSIEVNVSPDISVCIIPYNNRLDLVKQEINRRENVTLFDNIESIQRWDEFAEEVWAAHPYAKNSKLSRNTLYKSPLLRKLAALDGDFEKFVFYDADSLAMKPLEDLFSRLDEYDFIFDDWEHGKSSDVAALNIPLIEKSGLYAEEDVRPKLHCSSFFASKQGLLAPEEIERLKTLLIEKNEIEWVTRWWDDAFLFNYLTLRTECQLFNFTLSPNGEERTGNCANADPFVNIDNVLYNQQGLKPIYRLHYMNYSTNDFVRLCKGEDLNIRYRDEFLHYRFLKEPEKKPLRLKKPGLVSKANYYIKKAMNKVRLAVS
>NC_019678.1|WP_015120124.1|5180613_5181837_+|glycosyltransferase
MKILMLSSTFPYPPTRGGTQVRTFNLLKYLTKNHRVTLVTQPETGVTESEITGLRDCVDELVLFNRPHDSGTTGGILKKVQRLTKFVGKGIPPSVLNRYSVDMQNWIDNYVEAGKCDTITSEHSVNEIYIRPNFHKKIRTVVNVHSSVYGTCLNQLQNGISENTFRDRINLPLLRRYENTYCNKFSAIVATTEEDKIQLREFNSESEMMVIPNGVDLVMFPNRIADPGGHRLVFIGAMDNLANIDAVCFFCNEVLPEVQKKYPNTTFDIVGSRPVAEVLALKEKPGVNVTGKVPSMAEYLHKSTVCIVSMRTGFGIKNKTLEAMAAGIPVVGSDRGLEGLNVDGDSLELRALRANQPQEYINAISKLFENPQLRAELSYNARKLVETEFTWESAGRRYEQVCVGKGS

Crispr_ID: NC_019678_23

• CRISPR_ID: NC_019678_23
• CRISPR_location: 5166890-5167505
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 8 spacers
• Cas_protein_info: RT

Consensus repeat of NC_019678_23

Consensus_repeat	Method
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	CRISPRCasFinder
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	CRT
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	PILER-CR

spacers of NC_019678_23

>23.1|5166926|37|NC_019678|CRISPRCasFinder,CRT
ACCGAGGCAAAGGCTTTATTATCTTTTATATTAGAAA
>23.2|5166999|37|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AAACCCAAAACTTCTTGTAGCTTCAAGAAAAGCCACA
>23.3|5167072|34|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TAGCGTCCGATGTTGGATTATTCCGGCATTATAT
>23.4|5167142|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TGAAGTTCTGGTGTACGAAACAGCAGACGGAAA
>23.5|5167211|38|NC_019678|CRISPRCasFinder,CRT,PILER-CR
ATATCAAGACGCTATCCAATGGGAAGGCGCATCTATTG
>23.6|5167285|41|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TTCTCAAATGCTAGCTTATTAGATTCTGGAAACTCTAGAAC
>23.7|5167362|36|NC_019678|CRISPRCasFinder,CRT,PILER-CR
GCTAAGAAGGAAAAGCCAGTGCCCACCCCCTCACCT
>23.8|5167434|36|NC_019678|CRISPRCasFinder,CRT,PILER-CR
GTTGCAAAAATGGCAGCCGCAAATTTTGCTGTGATT

CRISPR arrays and Neighbor proteins around NC_019678_23

CRISPR arrays

The CRISPR arrays of NC_019678_23

>merge|NC_019678|23|5166890-5167505|CRISPRCasFinder,CRT,PILER-CR
GCTTTCATCCCCGCTGAGGGGAGTTGGTTTGGAAAGACCGAGGCAAAGGCTTTATTATCTTTTATATTAGAAAGTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAGAAACCCAAAACTTCTTGTAGCTTCAAGAAAAGCCACAGTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAGTAGCGTCCGATGTTGGATTATTCCGGCATTATATGTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAGTGAAGTTCTGGTGTACGAAACAGCAGACGGAAAGTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAGATATCAAGACGCTATCCAATGGGAAGGCGCATCTATTGGTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAGTTCTCAAATGCTAGCTTATTAGATTCTGGAAACTCTAGAACGTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAGGCTAAGAAGGAAAAGCCAGTGCCCACCCCCTCACCTGTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAGGTTGCAAAAATGGCAGCCGCAAATTTTGCTGTGATTGTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG

>NC_019678|23|20|5166890-5167505|CRISPRCasFinder
GCTTTCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG	ACCGAGGCAAAGGCTTTATTATCTTTTATATTAGAAA
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	AAACCCAAAACTTCTTGTAGCTTCAAGAAAAGCCACA
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	TAGCGTCCGATGTTGGATTATTCCGGCATTATAT
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	TGAAGTTCTGGTGTACGAAACAGCAGACGGAAA
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	ATATCAAGACGCTATCCAATGGGAAGGCGCATCTATTG
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	TTCTCAAATGCTAGCTTATTAGATTCTGGAAACTCTAGAAC
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	GCTAAGAAGGAAAAGCCAGTGCCCACCCCCTCACCT
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	GTTGCAAAAATGGCAGCCGCAAATTTTGCTGTGATT
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG

>NC_019678|23|8|5166890-5167505|CRT
GCTTTCATCCCCGCTGAGGGGAGTTGGTTTGGAAAG	ACCGAGGCAAAGGCTTTATTATCTTTTATATTAGAAA
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	AAACCCAAAACTTCTTGTAGCTTCAAGAAAAGCCACA
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	TAGCGTCCGATGTTGGATTATTCCGGCATTATAT
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	TGAAGTTCTGGTGTACGAAACAGCAGACGGAAA
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	ATATCAAGACGCTATCCAATGGGAAGGCGCATCTATTG
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	TTCTCAAATGCTAGCTTATTAGATTCTGGAAACTCTAGAAC
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	GCTAAGAAGGAAAAGCCAGTGCCCACCCCCTCACCT
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	GTTGCAAAAATGGCAGCCGCAAATTTTGCTGTGATT
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG

>NC_019678|23|8|5166963-5167505|PILER-CR
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	AAACCCAAAACTTCTTGTAGCTTCAAGAAAAGCCACA
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	TAGCGTCCGATGTTGGATTATTCCGGCATTATAT
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	TGAAGTTCTGGTGTACGAAACAGCAGACGGAAA
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	ATATCAAGACGCTATCCAATGGGAAGGCGCATCTATTG
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	TTCTCAAATGCTAGCTTATTAGATTCTGGAAACTCTAGAAC
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	GCTAAGAAGGAAAAGCCAGTGCCCACCCCCTCACCT
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG	GTTGCAAAAATGGCAGCCGCAAATTTTGCTGTGATT
GTTTCCATCCCCGTTGAGGGGAGTTGGTTTGGAAAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015120114.1|5163534_5165820_+|catalase/peroxidase-HPI	unknown	unknown	gnl|CDD|237891
NC_019678.1|WP_015120112.1|5155647_5158536_+|isoleucine--tRNA-ligase	unknown	unknown	gnl|CDD|215452
NC_019678.1|WP_015120120.1|5175820_5176678_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120124.1|5180613_5181837_+|glycosyltransferase	unknown	unknown	gnl|CDD|274425
NC_019678.1|WP_015120108.1|5151573_5152842_+|hypothetical-protein	unknown	unknown	gnl|CDD|235046
NC_019678.1|WP_157229438.1|5149597_5150383_-|trypsin-like-serine-protease	unknown	unknown	gnl|CDD|379142
NC_019678.1|WP_015120105.1|5147595_5149554_-|serine-protease	unknown	unknown	gnl|CDD|379142
NC_019678.1|WP_015120121.1|5176844_5177792_-|glycosyltransferase	unknown	unknown	gnl|CDD|133055
NC_019678.1|WP_015120123.1|5179131_5180145_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120107.1|5150640_5151192_-|hypothetical-protein	unknown	unknown	gnl|CDD|372967
NC_019678.1|WP_015120117.1|5169616_5170582_+|NTF2-domain-containing-protein	unknown	unknown	gnl|CDD|370323
NC_019678.1|WP_015120122.1|5178058_5178979_-|polysaccharide-pyruvyl-transferase-family-protein	unknown	unknown	gnl|CDD|377253
NC_019678.1|WP_015120109.1|5153008_5153302_-|acylphosphatase	unknown	unknown	gnl|CDD|237713
NC_019678.1|WP_015120125.1|5182146_5182440_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120118.1|5170775_5173397_-|cell-division-protein-FtsK	unknown	unknown	gnl|CDD|224588
NC_019678.1|WP_015120111.1|5154027_5155209_+|gluconolactonase	unknown	unknown	gnl|CDD|308585
NC_019678.1|WP_015120110.1|5153575_5153944_+|DUF1823-family-protein	unknown	unknown	gnl|CDD|370156
NC_019678.1|WP_015120116.1|5167988_5168873_-|ParA-family-protein	unknown	unknown	gnl|CDD|224113
NC_019678.1|WP_015120119.1|5173666_5175754_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379062
NC_019678.1|WP_015120113.1|5159727_5161521_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019678.1|WP_015120113.1|5159727_5161521_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	4.7e-50	164.9	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015120114.1|5163534_5165820_+|catalase/peroxidase-HPI	gnl|CDD|237891	PRK15061, PRK15061, catalase/peroxidase.	0
NC_019678.1|WP_015120112.1|5155647_5158536_+|isoleucine--tRNA-ligase	gnl|CDD|215452	PLN02843, PLN02843, isoleucyl-tRNA synthetase.	0
NC_019678.1|WP_015120124.1|5180613_5181837_+|glycosyltransferase	gnl|CDD|274425	TIGR03087, stp1, sugar transferase, PEP-CTERM/EpsH1 system associated. Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.	2.83409e-60
NC_019678.1|WP_015120108.1|5151573_5152842_+|hypothetical-protein	gnl|CDD|235046	PRK02507, PRK02507, proton extrusion protein PcxA; Provisional.	8.66893e-176
NC_019678.1|WP_157229438.1|5149597_5150383_-|trypsin-like-serine-protease	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	9.4622e-22
NC_019678.1|WP_015120105.1|5147595_5149554_-|serine-protease	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	2.08614e-24
NC_019678.1|WP_015120121.1|5176844_5177792_-|glycosyltransferase	gnl|CDD|133055	cd06433, GT_2_WfgS_like, WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	8.77831e-34
NC_019678.1|WP_015120107.1|5150640_5151192_-|hypothetical-protein	gnl|CDD|372967	pfam14218, COP23, Circadian oscillating protein COP23. This family includes the circadian oscillating protein COP23 from Cyanothece sp. (strain PCC 8801). The levels of this peripheral membrane protein display a circadian oscillation.	8.21797e-50
NC_019678.1|WP_015120117.1|5169616_5170582_+|NTF2-domain-containing-protein	gnl|CDD|370323	pfam09150, Carot_N, Orange carotenoid protein, N-terminal. Members of this family adopt an alpha-helical structure consisting of two four-helix bundles. They are predominantly found in prokaryotic orange carotenoid protein, and carotenoid binding proteins.	7.69522e-95
NC_019678.1|WP_015120122.1|5178058_5178979_-|polysaccharide-pyruvyl-transferase-family-protein	gnl|CDD|377253	pfam04230, PS_pyruv_trans, Polysaccharide pyruvyl transferase. Pyruvyl-transferases involved in peptidoglycan-associated polymer biosynthesis. CsaB in Bacillus anthracis is necessary for the non-covalent anchoring of proteins containing an SLH (S-layer homology) domain to peptidoglycan-associated pyruvylated polysaccharides. WcaK and AmsJ are involved in the biosynthesis of colanic acid in Escherichia coli and of amylovoran in Erwinia amylovora.	1.32303e-07
NC_019678.1|WP_015120109.1|5153008_5153302_-|acylphosphatase	gnl|CDD|237713	PRK14423, PRK14423, acylphosphatase; Provisional.	6.57845e-48
NC_019678.1|WP_015120118.1|5170775_5173397_-|cell-division-protein-FtsK	gnl|CDD|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	1.03629e-57
NC_019678.1|WP_015120111.1|5154027_5155209_+|gluconolactonase	gnl|CDD|308585	pfam03022, MRJP, Major royal jelly protein. Royal jelly is the food of queen bee larvae, and is responsible for the high reproductive ability of the queen. Major royal jelly proteins make up around 90% of larval jelly proteins. This family also the sequence-related yellow protein of drosophila which controls pigmentation of the adult cuticle and larval mouth parts.	8.0011e-34
NC_019678.1|WP_015120110.1|5153575_5153944_+|DUF1823-family-protein	gnl|CDD|370156	pfam08853, DUF1823, Domain of unknown function (DUF1823). This presumed domain is functionally uncharacterized.	3.30911e-78
NC_019678.1|WP_015120116.1|5167988_5168873_-|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	4.70696e-53
NC_019678.1|WP_015120119.1|5173666_5175754_-|AAA-family-ATPase	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	1.14905e-05
NC_019678.1|WP_015120113.1|5159727_5161521_-|group-II-intron-reverse-transcriptase/maturase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	4.85368e-123

Protein sequences

>NC_019678.1|WP_015120114.1|5163534_5165820_+|catalase/peroxidase-HPI
MNNNPQSAPAQCPFRGTRVGGALGSKPQTDDWWPNRLQVELLHQNSPLANPLGDFDYKQAFQKIDFQQLKKDIKTLLTDSKDWWPADYGNYGPQMIRMAWHAAGTYRIADGRGGASRGMQRFAPINSWWDNGNTDKSRRLLWPIKQKYGAALSWADLMILVGNCSLEIMGLKTFGYGGGRIDAWEADRATYWGPEFWNGEAFGENGKEHEGHPNEMVTRTIRWEGEPKDEYYDLENPLGASHQALIYVDPEGPDGSGDPLASARDIRETFARMAMNDEETVALIAGGHAFGKSHGMVAADKIGPAPEGAPIQAMGLGWQNPEGTGFAEYTMTNGIEGSWTPNPTQWDNSYLENLFKYDWEKTKSPTGAIQWKPVDPGAPKTPDAHKTGVEHALMMMTSDVALKEDSAYHQVCQRFLGDFEYFSDTFARAWYKLTHRDMGPKVRYLGPEVPEEDLTWQDPIPQLDHDVVNDADISSLKNKILASGLSVSALVSAAWASASNYRDSDKRGGANGARVRLDPQKDWEVNRPQELSQVLSTLERIQAEFNGNQSGNKKVSMADLIVLGGCAAVEKAAKDAGIDTSVPFTPGRMDTTLEVTDVESFEWLKPVSDGFRNYHNEAVGYKVKAERIFLDRAQLLTLTAPEWTVLVGGLRALDQNWDNSKHGIFTDRPGVLTNDFFRVLTSMEYEWKPIDNREMLFNICDRNTGETKFTATRCDLIFGSNAELRQVAEVYGADDGHERMIKDFVAAWNKVMMLDRFDVSA
>NC_019678.1|WP_015120113.1|5159727_5161521_-|group-II-intron-reverse-transcriptase/maturase
MVQSTIVNVTERATDWNSIKWKHANRVVTRLRQRIFKATRDGDLKKIRSLQKLLMRSYSNIVLSVRRVTQLNSGKKTAGVDKLLVLTPGARGTLVDILTRCPPWKPLPVKRVYIRKSNGKQRPLGIPCVIDRCLQAIVKNALEPYWEAQFERTSYGFRPGRGVHDAIERIHSMSKANSTKSWVVDADIEGCFDNIAHSPLLKTIGNFPAKKLIQQWLKAGYVDKGVFNDTETGVPQGGIISPLLANIALHGMESALGIRYDKHGHTIGNRGIVRYADDLVVFCKTQEDAACVVETLSHWMKSKGLALSKAKTNIVHLSEGFNFLSFNIRWYKDKNTKIGRKVLIKPSKEALQDVRNKIKQVWLENKSSNVNYLISKLNPIIRGVANYYRTVVSSHIFHKLDTWMYVRENRYAKRVHPKKSSGWRKHKYWGRLNFDRNDNWVFGEPVAVDGFPGISKLVNPEGDKRTGQYLLKFSWFNIRRHTLVKGDASYDNPDLVKYWESRTKRKSQNLIPSYQKLARKQGYKCCVCGESLFNDEPIQKHHKVPQSRGGKDTYANLELMHYYCHRQVHSVAPGCEDEVFVQDLQELNPVPGSVRIG
>NC_019678.1|WP_015120112.1|5155647_5158536_+|isoleucine--tRNA-ligase
MTESGSYKKTVNLPKTKFDMRANATKREPEIQKFWAENKVYERLSQENPGELFILHDGPPYANGSLHIGHALNKILKDIINRYKILQGRKISYVPGWDCHGLPIELKVLQTMKSSERQELTPLKLRNKAKDFAWEAVNEQRESFKRYGVWGDWEHPYLTSNPQYEAEQIAVFGDMFLKGYIYRGLKPVHWSPSSKTALAEAELEYPEGHTSPSIYAAFPMTNLADAAKDKLSEFLPDLGVAIWTTTPWTIPGNLAVAVNPDLNYAVVEVENLSAVDFKYLIVAADLAERLSETFGAKLTVKATFKGKELENSTYRHPLFDRESPVIIGGDYITTESGTGLVHTAPGHGQEDYIVGQKYNLPILAPVDANGKFTEEAGKFVGLKVVGAKDQISEGNQAIIDALTEAKSLIKHEPYAHKYPYDWRTKKPTIFRATEQWFASVEKFRETALEQIKSVQWIPAQGQNRITPMVADRNDWCISRQRSWGVPIPVFYDEETNEVVLNEDTIKHVQAIIAEKGSDAWWELSVEDLMPEKYRNDGRKYRKGMDTMDVWFDSGSSWASVVEQRPELRYPADVYLEGSDQHRGWFQSSLLTSVAVNGVAPYKTVLTHGYTLDEKGFKQSKSLGNVIDPRVVIEGGKNQKQEPAYGADVLRLWVSSVDYTNDVGIGKNTLKQIMDIRNKIRNTTRFLLGNLHDFNPETDAVAFEELAEIDKYMLHRMTEVFTEITNAYETFQFSRFFQAVQNFCIVDLSNFYLDVGKDRLYISSENGSRRRSCQTVMQIALENLTKAIAPVLAHMAEDIWQFIPYETPQKSVFEAGWVQLEDKWKNPDIVKFWDKIRQIRNDVNKVLEEARIDKMIGSSLEAKVLLYVKDEELRNAIKSLNDNSNNNVDELRYLFLTSQAEILDNPGVDDCKHKMQSDNWEIGVAKADGHKCDRCWNYSTKVGESTEHPLLCERCVNALAGEF
>NC_019678.1|WP_015120111.1|5154027_5155209_+|gluconolactonase
MRFSKLLLSSIAVCITVGLVLINNPVNAQRNLPQEKTVGNIETVATFNDAMPTGVTVSQTGRVFVNFPRWGDKVDFTVAEVKNNRSIPYPNAEINVANKDKPKDSLLSVQSVVIDALDRLWILDTGSIEFAPTINGGAKLVGVDLKTNKIFKKIVFPEDVALKTTYLNDVRFDLRRGKEGMAFITDSSLTGANAIIIVDLATGKSWRRLNNHPSTKAEDIDKFLPIVEGQPLMSRPPNAEPSPFKVGADGIAISSDGGRLYYCPLSGRTLYSVNVDALVQPASEEQVAKTVINHGDKGGASDGLESDAQNRIYVTNYEDNAILRRLPNGMYETVVHDSRLLWPDTLSLATNGYLYFTANQLHRQPNFHNGKDLRQKPYSIFRTKVDAKPVLLK
>NC_019678.1|WP_015120110.1|5153575_5153944_+|DUF1823-family-protein
MELPPLTTDTIWAILNKEIDDTTVNQLVWHYLGYGYDESTGKWDANNASEEWRSEYPEPPDFIANRPPTVKLTRSIPKENKQMLKEFLGFTGYKIGEFGPRETRRATAANWLLSYMKINGYC
>NC_019678.1|WP_015120109.1|5153008_5153302_-|acylphosphatase
MSNPTLPKQTRAHVFISGKVQGVGYRYSTMNAARNLGLNGWVKNLPDSRVEAVFEGASETVEKMIRWCHQGSDAAVVKDVQVEYSQLEGLQGFEIVS
>NC_019678.1|WP_015120108.1|5151573_5152842_+|hypothetical-protein
MYKSKKSLFQAIQQSWRFINKWFLDTPQRALLLAYEAALKIRDIEDKHFSGNKISEESNIYTANVLSYWQAELEKYLKTINFRLAEFQRSSSLLTVTDKTFLDKLKFIDEVTARYAVDKEFTTKRRIVTTQSNTQEQKEHYELDYDDTDINKMKVKPVTVKTGLFPGSITRSFKKIIKELSPRAEEKTVRDFRTSSKRTRIALKFLATLIIVPFLTYLFLKQLVIYPIVERVRTDAATDAFLNSHIEEQVLQEFKFYQQELKFEKLILQAPLLSSEIQQKQKERAIKIAEEFHHKNNSAISNVFADIISLIVFAFIIATSKREVAILQLFIDDTVYGLSDSAKAFLIILLTDMFVGFHSPHGWEVLLEGIAKHLGITPTRDVIFLFIATFPVILDTICKYWIFRYLSRISPSALATFKEMNE
>NC_019678.1|WP_015120107.1|5150640_5151192_-|hypothetical-protein
MKLGLLVRVLSGAAISSLTVFTAVTFSNQPSYAGGATFYCGTSTYRNKSVPTTFARTQDGKKVPIVRWISNYFPPPWTPKKRCGAVSNKFQRFYDHGILRYITADTLKGQPVLCATPSPGIGCTSDTVLFTLKPGSNPQATIRRLLDRRGLAGGMVLNESANSVDVDFEMYLQSGSNEARKRK
>NC_019678.1|WP_157229438.1|5149597_5150383_-|trypsin-like-serine-protease
MHFWHRWKFIGCFSCLSLVLSVSNLCCTLSAGSTNAVCENQSQAKQSSILSAKQLRHRAEQISVNVMAPSIVGTGFLLKKQGCVYTVVTNAHVLRAGKPPYRIKTSDNRIWEAQTRYVASEKGDDLAILEFRTRGESYPVAPIGVKPIPGTAVVAAGFPFVEGDTRVKFRLTAGKVSLVLDKALQGGYQIGYTNDIQKGMSGGALLNLRGEVVGVNGMHAFPLWDIPSVFESGEEADKALHEKIVRLSWAVPMQKVERLNR
>NC_019678.1|WP_015120105.1|5147595_5149554_-|serine-protease
MKLIYALSPVMLTVSTILVQPQFALAQSSADVAKIAKKITVLIDNQDSPGSGVIIQRSGNTYTVLTAAHVVRKTSDYNIVTSDGQRYKLNKSNIKPLQGVDLAVVQFDSNQQYATAKLGNSSNSTEGTTAYVAGFPKPTAAVSNSLYTFMDGRIIANASQSLRDGYSLVYSIDTLPGMSGGPILNQKGELIGVHGRGDTTENFNISDVNPNIIIKTGRNLGIPISTFTKQFKTAGLDTPKVAAAPNNAATNKPLADDFYLQSVEKRNKADFQGAIKDLNQAIKINPKYAFAYYRRAEARQNTGEREKAIKDLQKAAELFSEQGNKSDAFRSQGSMRMLKQDYPGAIAAFSQAIKLNPKDTDAYNERGMTRVQSGDLKGALADYNKSLSLQPSDAYAYMGRSFTHLKLQDKISAIADVNQAISIAPNYALPYLILGVIHYNFGDTPKAITTFNKASQLLAAQGNQSYAHGSQALAFQLSNNYPAAINSFTKAIKANPQDAEMYELRGDVYSRNGNIKKALADYAQAIRINPNDASAYTSRASIRLVQQKDSQGALTDLNKALSLDPSQDKAYFFRTIIRIQQKDRQRALADINNAIRYVVSDADKYMYKGIKSALQGNKPEAKNNLQRSANLYQLRGDKASYNEVMKLISMIN
>NC_019678.1|WP_015120116.1|5167988_5168873_-|ParA-family-protein
MGYVISTANMKGGVGKTTLTVNLATCLAKNHGKRVLVLDLDTQISATLSLMSPIEFAKLRKKRRTLRYLIDDIVKSSDKAKLSIQEIIQPSVNNLSGLDLLPGDIDLYDEFVVSQMLHQQAVNLSENDFEVIWNRFERVLLGKILEPVRNDYDFILLDCAPGYNLLTRSALATSNFYVLPAKPEPLSVVGIQLLERRIAQLKESHEHEANIDISMLGIVFTMSNSNMLTGRYYKQVINRVYQDYGAEKICQTQIPVDVNVAKAVDSFMPVVLNSPQSGGSKAFNQLTQELLNKL
>NC_019678.1|WP_015120117.1|5169616_5170582_+|NTF2-domain-containing-protein
MALTIDSAQNIFAGTQVPSPIPATIALFDQLSVDDKLAYLWYAYTEMGKTITPAAPGAARLQLAESLLKQIKEMSAEEQTRVMRDLANRSDSPISRSYGFFSVNTKLAFWFELGELMKQGVVAPIPANYQMSEGVKVVLEATKKLDAGQQITVLRNTVVDMGFDTSGMAPSSSKAPAEPMFERSGETVSDVKIEGVNEPAVTKYIEAMNADNFDAAVSLFADDGALQPPFHKPIVGKQAIGKYMREEAQGLNMMPKKGISESRPDGSKQLKITGVVETPWFGANVGMNIAWRFLVNPQGKIFFVAIDMLASPQELLNLGRK
>NC_019678.1|WP_015120118.1|5170775_5173397_-|cell-division-protein-FtsK
MHYLTDTAQIRATINQFRSSKILWLDTEVADCRTPNPRLSLIQVLANPDDSTGEFAYILDVLDKPDLARYFIDQIMVNPQIEKVFHNASFDLKYLGGKLIPNVTCTLKIARKITRYKLKTSNLKLKTLATELCQFTDVDTESGASDWGKRPLIGKQLYYAAMDVVYLAAVHRQLISFNSVDKNSILKMAANKNKLTVTKVRIAFECPRLFYINDKFGGKTLFLPKDTATGIGSVFHSFADEFVRFTLREPRFKELFKAEASQLDIEEVAVEMQQLFYKAKFYPYLQQVTKTDKSRATPLLLVWQGLQNVIKRFAQILIVNRGYCSGSSVIRKTFVSEARQLEHFFDLPNKTRQLIRGEYDCLTYNFERQRLCLLEFKTYQSIDPSAQLAQVSLYGYMLFQQKQVPVDSAVYCVLPEFKEYYYGWEELENTVNQLIPYKLQQMQEWLSWKPSQPNCPPSTTQPYLCEICPQQEKCQSYFGDSIEIPPTPLNEAGLKDEEDLDRENKKYIVPDIQIPSTPPEKEKLKEENSVNADATAEELVTTLQSFGINVDFVGAAVAPSFIRVKLKPQLGVKFNSIQKLYADLQIQMGLENPPLIAPQAGYVSVDLPNPNRKAAFFDDYLKPQKSQITASVKIAIGVNLEGKLVEADLSDPNTCHFLVGGTTGSGKSEFLRSQLLSLLIRYSPQQLKIALVDPKRVTFPEFEKMPWLYSSVVKDSEKAIDLMDKLVSEMEFRYQQFEKTECADLGSYNQRSDQPLARIVCIFDEYADFMAEKESRNALEQSIKRLGAMARAAGIHLIIATQRPEAKVVTPIIRSNLPGRVALRTASEADSTIVLGGKKTAAAYLLGKGDLLYQVGAKLHRLQSLYAKKIKLP
>NC_019678.1|WP_015120119.1|5173666_5175754_-|AAA-family-ATPase
MTPINNIIKRELNPFDLINLKPGNFWGEKQDSDNSVDSIHQEVITEIEGLLDSVNQDNRSRSVLLLGDSGSGKSYLLGRLKRTLNKKAFFAYIGPWADSDYIWRHVLRSTVDSLIQIPEGREESQLILWLKSLSAFTRRNLKQRLFSDSIWQFMQSDRRKFIHHLKTTYSQAGLYNPDFFFGVLHDLTDPELYPIACEWLRGDDLSEESMQILKVKSCIDTEDAAKNILANFGRISIQTQPIVLCFDNLDNIPRLSDESQDFQSLFNVNTTIHNNYLKNFLVVVSIITNTWKLNSDRIQQADKVRIDKELRLKRINLEQAEALWAYRLKPLHHQVKPQPISPIFPLNRKLLQQSFPSGKTLPREVLVIGQKEYKKYKFSLVDSTVVKPIPEPEVITVPEEIKLPVPQPQIQAETIDAEFQLLWQKEYKKTQGKNQKITLFSAPDLIRMLEEALQALEVPDIKTKLLRGKYTSYSLSYRKSKKGNQIGIVWTEDSGMASFYNVMSASQKVIQSKGCETLYLIRSGSVGTSKLKGYQLYQKIFHSSKSSKHIHLKPSLASVHQLATYHNLVNSAVAQELVLSGRVIKLDELQELIRNSLIFEKCTLLQDLKVVPEPDDSEDGEDVIDLTPVNDFLFNLVKTQGFMGVPTLISQCMTQFSDAREDDVKMLIQDLCQEEKVKIIDPKAKSEDQLICLIA
>NC_019678.1|WP_015120120.1|5175820_5176678_-|hypothetical-protein
MDTNELKFLLKLLGCENYRSTLSGNAFKSFKGKNTICQNLGDREIIDFSREVAAVKILPPGQALLKLDAAEVPIEEKELRILENVAKVSGKVAPSKIKSSLKAAQKEEILRSLSDRGLIEAEIKLKKKKAEVWLTQRGIEFLRDDFSPKKGANPAISLDLLNNYLRFLRKSLKSQSQEATVTAPINNSEPVTQKSKAINDEEILQIIQKLDNELGTKDYLPIFYLREKLQPSMSRNELDQVLFKLQADDKIELSTLQEASAYTPEQIESGIKQNVGGPLFFISIF
>NC_019678.1|WP_015120121.1|5176844_5177792_-|glycosyltransferase
MPKVSICIPTFNRIDLLPFAIDSVLKQTYQDFELIVCDDGSSDGTADLMSKYEDSRIKYIRHRQNIGKSNNMLSGFDAATGDYFIKFDDDDRLTPNFIAETAAILDRDSNIDFVGTDHWIIDIDNVRDQTQTEENSRQWGREDLPGGVVNNLLQAVFVNQSFQIGATLFRRQTVVEVGFMQPNWQNCEDNDLFVRLALAGKKGYYLPKLLMEYRVHAEQQGINRAIPYLTGKQQYLQSYKFDSQELENIRLNRLRETQLLLGLRLIESGETEKGRELVNKGKSFSTAKAWTGLGLSLLPVGVRGKAFDALRKVKG
>NC_019678.1|WP_015120122.1|5178058_5178979_-|polysaccharide-pyruvyl-transferase-family-protein
MKLFYFSFPNGMSNFGDDLNPWLWEKLLPGVFDQDNKSIFVGIGTLLNDYVPKANKTAVFASGVGYSKGLPAIDESWKIYCVRGPLSAKKLGIDPQLAVTDGALLIRKVYEPSSIKKTKFAYMPHITHIIHGGNAWKDICEEAGISYIDPRWSTEEVLSAICETEVLLTEAMHGAIIADALRVPWIPVLTSTRIFPWKWQDWCLTVGVDYKPQYLMPWENVYSPGHGTVSSLRFKKNYACQAPIRLFKTLLQKESQKMANQLADIAKTSKPNLSSDTRIQQLTLQLEERLQQFQEDLTAGCFAVSN
>NC_019678.1|WP_015120123.1|5179131_5180145_-|hypothetical-protein
MQRFGIYTLANDIVYDQLVALLNSIEVNVSPDISVCIIPYNNRLDLVKQEINRRENVTLFDNIESIQRWDEFAEEVWAAHPYAKNSKLSRNTLYKSPLLRKLAALDGDFEKFVFYDADSLAMKPLEDLFSRLDEYDFIFDDWEHGKSSDVAALNIPLIEKSGLYAEEDVRPKLHCSSFFASKQGLLAPEEIERLKTLLIEKNEIEWVTRWWDDAFLFNYLTLRTECQLFNFTLSPNGEERTGNCANADPFVNIDNVLYNQQGLKPIYRLHYMNYSTNDFVRLCKGEDLNIRYRDEFLHYRFLKEPEKKPLRLKKPGLVSKANYYIKKAMNKVRLAVS
>NC_019678.1|WP_015120124.1|5180613_5181837_+|glycosyltransferase
MKILMLSSTFPYPPTRGGTQVRTFNLLKYLTKNHRVTLVTQPETGVTESEITGLRDCVDELVLFNRPHDSGTTGGILKKVQRLTKFVGKGIPPSVLNRYSVDMQNWIDNYVEAGKCDTITSEHSVNEIYIRPNFHKKIRTVVNVHSSVYGTCLNQLQNGISENTFRDRINLPLLRRYENTYCNKFSAIVATTEEDKIQLREFNSESEMMVIPNGVDLVMFPNRIADPGGHRLVFIGAMDNLANIDAVCFFCNEVLPEVQKKYPNTTFDIVGSRPVAEVLALKEKPGVNVTGKVPSMAEYLHKSTVCIVSMRTGFGIKNKTLEAMAAGIPVVGSDRGLEGLNVDGDSLELRALRANQPQEYINAISKLFENPQLRAELSYNARKLVETEFTWESAGRRYEQVCVGKGS
>NC_019678.1|WP_015120125.1|5182146_5182440_-|hypothetical-protein
MHKNTSYLLALVLAVGSALVAVPSHAQTGAENNQNIAVSSQSSISNESIVSKLKKSKAANQNEAIKISQSQSSSATANTEEPVRKNLLHSRIGWLSQ

Crispr_ID: NC_019678_24

• CRISPR_ID: NC_019678_24
• CRISPR_location: 5173408-5173573
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 1 spacers
• Cas_protein_info: RT

Consensus repeat of NC_019678_24

Consensus_repeat	Method
TATTAATTAAATATTATTTAAAACTCTCACTATCTCGTTACAAGGTTCTACCT	CRISPRCasFinder

spacers of NC_019678_24

>24.1|5173461|60|NC_019678|CRISPRCasFinder
CCAGAGTCAAGGCGGAGCCTTCTGTTAGGGATTCACAGTCTCCGGCTGGGAACCAGTTTC

CRISPR arrays and Neighbor proteins around NC_019678_24

CRISPR arrays

The CRISPR arrays of NC_019678_24

>merge|NC_019678|24|5173408-5173573|CRISPRCasFinder
TATTAATTAAATATTATTTAAAACTCTCACTATCTCGTTACAAGGTTCTACCTCCAGAGTCAAGGCGGAGCCTTCTGTTAGGGATTCACAGTCTCCGGCTGGGAACCAGTTTCTATTAATTAAATATTATTTAAAACTCTCACTATCTCGTTATAAGGTTCTACCT

>NC_019678|24|21|5173408-5173573|CRISPRCasFinder
TATTAATTAAATATTATTTAAAACTCTCACTATCTCGTTACAAGGTTCTACCT	CCAGAGTCAAGGCGGAGCCTTCTGTTAGGGATTCACAGTCTCCGGCTGGGAACCAGTTTC
TATTAATTAAATATTATTTAAAACTCTCACTATCTCGTTATAAGGTTCTACCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015120116.1|5167988_5168873_-|ParA-family-protein	unknown	unknown	gnl|CDD|224113
NC_019678.1|WP_015120114.1|5163534_5165820_+|catalase/peroxidase-HPI	unknown	unknown	gnl|CDD|237891
NC_019678.1|WP_015120120.1|5175820_5176678_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120124.1|5180613_5181837_+|glycosyltransferase	unknown	unknown	gnl|CDD|274425
NC_019678.1|WP_015120108.1|5151573_5152842_+|hypothetical-protein	unknown	unknown	gnl|CDD|235046
NC_019678.1|WP_044291062.1|5186983_5187169_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120112.1|5155647_5158536_+|isoleucine--tRNA-ligase	unknown	unknown	gnl|CDD|215452
NC_019678.1|WP_015120121.1|5176844_5177792_-|glycosyltransferase	unknown	unknown	gnl|CDD|133055
NC_019678.1|WP_015120123.1|5179131_5180145_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120117.1|5169616_5170582_+|NTF2-domain-containing-protein	unknown	unknown	gnl|CDD|370323
NC_019678.1|WP_015120122.1|5178058_5178979_-|polysaccharide-pyruvyl-transferase-family-protein	unknown	unknown	gnl|CDD|377253
NC_019678.1|WP_015120109.1|5153008_5153302_-|acylphosphatase	unknown	unknown	gnl|CDD|237713
NC_019678.1|WP_015120125.1|5182146_5182440_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120118.1|5170775_5173397_-|cell-division-protein-FtsK	unknown	unknown	gnl|CDD|224588
NC_019678.1|WP_015120111.1|5154027_5155209_+|gluconolactonase	unknown	unknown	gnl|CDD|308585
NC_019678.1|WP_015120110.1|5153575_5153944_+|DUF1823-family-protein	unknown	unknown	gnl|CDD|370156
NC_019678.1|WP_015120119.1|5173666_5175754_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379062
NC_019678.1|WP_015120127.1|5185127_5186627_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_157229439.1|5183043_5184735_-|iron-uptake-porin	unknown	unknown	gnl|CDD|335962
NC_019678.1|WP_015120113.1|5159727_5161521_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019678.1|WP_015120113.1|5159727_5161521_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	4.7e-50	164.9	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015120116.1|5167988_5168873_-|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	4.70696e-53
NC_019678.1|WP_015120114.1|5163534_5165820_+|catalase/peroxidase-HPI	gnl|CDD|237891	PRK15061, PRK15061, catalase/peroxidase.	0
NC_019678.1|WP_015120124.1|5180613_5181837_+|glycosyltransferase	gnl|CDD|274425	TIGR03087, stp1, sugar transferase, PEP-CTERM/EpsH1 system associated. Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.	2.83409e-60
NC_019678.1|WP_015120108.1|5151573_5152842_+|hypothetical-protein	gnl|CDD|235046	PRK02507, PRK02507, proton extrusion protein PcxA; Provisional.	8.66893e-176
NC_019678.1|WP_015120112.1|5155647_5158536_+|isoleucine--tRNA-ligase	gnl|CDD|215452	PLN02843, PLN02843, isoleucyl-tRNA synthetase.	0
NC_019678.1|WP_015120121.1|5176844_5177792_-|glycosyltransferase	gnl|CDD|133055	cd06433, GT_2_WfgS_like, WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	8.77831e-34
NC_019678.1|WP_157229439.1|5183043_5184735_-|iron-uptake-porin	gnl|CDD|335962	pfam04966, OprB, Carbohydrate-selective porin, OprB family.	1.1107e-21
NC_019678.1|WP_015120117.1|5169616_5170582_+|NTF2-domain-containing-protein	gnl|CDD|370323	pfam09150, Carot_N, Orange carotenoid protein, N-terminal. Members of this family adopt an alpha-helical structure consisting of two four-helix bundles. They are predominantly found in prokaryotic orange carotenoid protein, and carotenoid binding proteins.	7.69522e-95
NC_019678.1|WP_015120122.1|5178058_5178979_-|polysaccharide-pyruvyl-transferase-family-protein	gnl|CDD|377253	pfam04230, PS_pyruv_trans, Polysaccharide pyruvyl transferase. Pyruvyl-transferases involved in peptidoglycan-associated polymer biosynthesis. CsaB in Bacillus anthracis is necessary for the non-covalent anchoring of proteins containing an SLH (S-layer homology) domain to peptidoglycan-associated pyruvylated polysaccharides. WcaK and AmsJ are involved in the biosynthesis of colanic acid in Escherichia coli and of amylovoran in Erwinia amylovora.	1.32303e-07
NC_019678.1|WP_015120109.1|5153008_5153302_-|acylphosphatase	gnl|CDD|237713	PRK14423, PRK14423, acylphosphatase; Provisional.	6.57845e-48
NC_019678.1|WP_015120118.1|5170775_5173397_-|cell-division-protein-FtsK	gnl|CDD|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	1.03629e-57
NC_019678.1|WP_015120111.1|5154027_5155209_+|gluconolactonase	gnl|CDD|308585	pfam03022, MRJP, Major royal jelly protein. Royal jelly is the food of queen bee larvae, and is responsible for the high reproductive ability of the queen. Major royal jelly proteins make up around 90% of larval jelly proteins. This family also the sequence-related yellow protein of drosophila which controls pigmentation of the adult cuticle and larval mouth parts.	8.0011e-34
NC_019678.1|WP_015120110.1|5153575_5153944_+|DUF1823-family-protein	gnl|CDD|370156	pfam08853, DUF1823, Domain of unknown function (DUF1823). This presumed domain is functionally uncharacterized.	3.30911e-78
NC_019678.1|WP_015120119.1|5173666_5175754_-|AAA-family-ATPase	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	1.14905e-05
NC_019678.1|WP_015120113.1|5159727_5161521_-|group-II-intron-reverse-transcriptase/maturase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	4.85368e-123

Protein sequences

>NC_019678.1|WP_015120118.1|5170775_5173397_-|cell-division-protein-FtsK
MHYLTDTAQIRATINQFRSSKILWLDTEVADCRTPNPRLSLIQVLANPDDSTGEFAYILDVLDKPDLARYFIDQIMVNPQIEKVFHNASFDLKYLGGKLIPNVTCTLKIARKITRYKLKTSNLKLKTLATELCQFTDVDTESGASDWGKRPLIGKQLYYAAMDVVYLAAVHRQLISFNSVDKNSILKMAANKNKLTVTKVRIAFECPRLFYINDKFGGKTLFLPKDTATGIGSVFHSFADEFVRFTLREPRFKELFKAEASQLDIEEVAVEMQQLFYKAKFYPYLQQVTKTDKSRATPLLLVWQGLQNVIKRFAQILIVNRGYCSGSSVIRKTFVSEARQLEHFFDLPNKTRQLIRGEYDCLTYNFERQRLCLLEFKTYQSIDPSAQLAQVSLYGYMLFQQKQVPVDSAVYCVLPEFKEYYYGWEELENTVNQLIPYKLQQMQEWLSWKPSQPNCPPSTTQPYLCEICPQQEKCQSYFGDSIEIPPTPLNEAGLKDEEDLDRENKKYIVPDIQIPSTPPEKEKLKEENSVNADATAEELVTTLQSFGINVDFVGAAVAPSFIRVKLKPQLGVKFNSIQKLYADLQIQMGLENPPLIAPQAGYVSVDLPNPNRKAAFFDDYLKPQKSQITASVKIAIGVNLEGKLVEADLSDPNTCHFLVGGTTGSGKSEFLRSQLLSLLIRYSPQQLKIALVDPKRVTFPEFEKMPWLYSSVVKDSEKAIDLMDKLVSEMEFRYQQFEKTECADLGSYNQRSDQPLARIVCIFDEYADFMAEKESRNALEQSIKRLGAMARAAGIHLIIATQRPEAKVVTPIIRSNLPGRVALRTASEADSTIVLGGKKTAAAYLLGKGDLLYQVGAKLHRLQSLYAKKIKLP
>NC_019678.1|WP_015120117.1|5169616_5170582_+|NTF2-domain-containing-protein
MALTIDSAQNIFAGTQVPSPIPATIALFDQLSVDDKLAYLWYAYTEMGKTITPAAPGAARLQLAESLLKQIKEMSAEEQTRVMRDLANRSDSPISRSYGFFSVNTKLAFWFELGELMKQGVVAPIPANYQMSEGVKVVLEATKKLDAGQQITVLRNTVVDMGFDTSGMAPSSSKAPAEPMFERSGETVSDVKIEGVNEPAVTKYIEAMNADNFDAAVSLFADDGALQPPFHKPIVGKQAIGKYMREEAQGLNMMPKKGISESRPDGSKQLKITGVVETPWFGANVGMNIAWRFLVNPQGKIFFVAIDMLASPQELLNLGRK
>NC_019678.1|WP_015120116.1|5167988_5168873_-|ParA-family-protein
MGYVISTANMKGGVGKTTLTVNLATCLAKNHGKRVLVLDLDTQISATLSLMSPIEFAKLRKKRRTLRYLIDDIVKSSDKAKLSIQEIIQPSVNNLSGLDLLPGDIDLYDEFVVSQMLHQQAVNLSENDFEVIWNRFERVLLGKILEPVRNDYDFILLDCAPGYNLLTRSALATSNFYVLPAKPEPLSVVGIQLLERRIAQLKESHEHEANIDISMLGIVFTMSNSNMLTGRYYKQVINRVYQDYGAEKICQTQIPVDVNVAKAVDSFMPVVLNSPQSGGSKAFNQLTQELLNKL
>NC_019678.1|WP_015120114.1|5163534_5165820_+|catalase/peroxidase-HPI
MNNNPQSAPAQCPFRGTRVGGALGSKPQTDDWWPNRLQVELLHQNSPLANPLGDFDYKQAFQKIDFQQLKKDIKTLLTDSKDWWPADYGNYGPQMIRMAWHAAGTYRIADGRGGASRGMQRFAPINSWWDNGNTDKSRRLLWPIKQKYGAALSWADLMILVGNCSLEIMGLKTFGYGGGRIDAWEADRATYWGPEFWNGEAFGENGKEHEGHPNEMVTRTIRWEGEPKDEYYDLENPLGASHQALIYVDPEGPDGSGDPLASARDIRETFARMAMNDEETVALIAGGHAFGKSHGMVAADKIGPAPEGAPIQAMGLGWQNPEGTGFAEYTMTNGIEGSWTPNPTQWDNSYLENLFKYDWEKTKSPTGAIQWKPVDPGAPKTPDAHKTGVEHALMMMTSDVALKEDSAYHQVCQRFLGDFEYFSDTFARAWYKLTHRDMGPKVRYLGPEVPEEDLTWQDPIPQLDHDVVNDADISSLKNKILASGLSVSALVSAAWASASNYRDSDKRGGANGARVRLDPQKDWEVNRPQELSQVLSTLERIQAEFNGNQSGNKKVSMADLIVLGGCAAVEKAAKDAGIDTSVPFTPGRMDTTLEVTDVESFEWLKPVSDGFRNYHNEAVGYKVKAERIFLDRAQLLTLTAPEWTVLVGGLRALDQNWDNSKHGIFTDRPGVLTNDFFRVLTSMEYEWKPIDNREMLFNICDRNTGETKFTATRCDLIFGSNAELRQVAEVYGADDGHERMIKDFVAAWNKVMMLDRFDVSA
>NC_019678.1|WP_015120113.1|5159727_5161521_-|group-II-intron-reverse-transcriptase/maturase
MVQSTIVNVTERATDWNSIKWKHANRVVTRLRQRIFKATRDGDLKKIRSLQKLLMRSYSNIVLSVRRVTQLNSGKKTAGVDKLLVLTPGARGTLVDILTRCPPWKPLPVKRVYIRKSNGKQRPLGIPCVIDRCLQAIVKNALEPYWEAQFERTSYGFRPGRGVHDAIERIHSMSKANSTKSWVVDADIEGCFDNIAHSPLLKTIGNFPAKKLIQQWLKAGYVDKGVFNDTETGVPQGGIISPLLANIALHGMESALGIRYDKHGHTIGNRGIVRYADDLVVFCKTQEDAACVVETLSHWMKSKGLALSKAKTNIVHLSEGFNFLSFNIRWYKDKNTKIGRKVLIKPSKEALQDVRNKIKQVWLENKSSNVNYLISKLNPIIRGVANYYRTVVSSHIFHKLDTWMYVRENRYAKRVHPKKSSGWRKHKYWGRLNFDRNDNWVFGEPVAVDGFPGISKLVNPEGDKRTGQYLLKFSWFNIRRHTLVKGDASYDNPDLVKYWESRTKRKSQNLIPSYQKLARKQGYKCCVCGESLFNDEPIQKHHKVPQSRGGKDTYANLELMHYYCHRQVHSVAPGCEDEVFVQDLQELNPVPGSVRIG
>NC_019678.1|WP_015120112.1|5155647_5158536_+|isoleucine--tRNA-ligase
MTESGSYKKTVNLPKTKFDMRANATKREPEIQKFWAENKVYERLSQENPGELFILHDGPPYANGSLHIGHALNKILKDIINRYKILQGRKISYVPGWDCHGLPIELKVLQTMKSSERQELTPLKLRNKAKDFAWEAVNEQRESFKRYGVWGDWEHPYLTSNPQYEAEQIAVFGDMFLKGYIYRGLKPVHWSPSSKTALAEAELEYPEGHTSPSIYAAFPMTNLADAAKDKLSEFLPDLGVAIWTTTPWTIPGNLAVAVNPDLNYAVVEVENLSAVDFKYLIVAADLAERLSETFGAKLTVKATFKGKELENSTYRHPLFDRESPVIIGGDYITTESGTGLVHTAPGHGQEDYIVGQKYNLPILAPVDANGKFTEEAGKFVGLKVVGAKDQISEGNQAIIDALTEAKSLIKHEPYAHKYPYDWRTKKPTIFRATEQWFASVEKFRETALEQIKSVQWIPAQGQNRITPMVADRNDWCISRQRSWGVPIPVFYDEETNEVVLNEDTIKHVQAIIAEKGSDAWWELSVEDLMPEKYRNDGRKYRKGMDTMDVWFDSGSSWASVVEQRPELRYPADVYLEGSDQHRGWFQSSLLTSVAVNGVAPYKTVLTHGYTLDEKGFKQSKSLGNVIDPRVVIEGGKNQKQEPAYGADVLRLWVSSVDYTNDVGIGKNTLKQIMDIRNKIRNTTRFLLGNLHDFNPETDAVAFEELAEIDKYMLHRMTEVFTEITNAYETFQFSRFFQAVQNFCIVDLSNFYLDVGKDRLYISSENGSRRRSCQTVMQIALENLTKAIAPVLAHMAEDIWQFIPYETPQKSVFEAGWVQLEDKWKNPDIVKFWDKIRQIRNDVNKVLEEARIDKMIGSSLEAKVLLYVKDEELRNAIKSLNDNSNNNVDELRYLFLTSQAEILDNPGVDDCKHKMQSDNWEIGVAKADGHKCDRCWNYSTKVGESTEHPLLCERCVNALAGEF
>NC_019678.1|WP_015120111.1|5154027_5155209_+|gluconolactonase
MRFSKLLLSSIAVCITVGLVLINNPVNAQRNLPQEKTVGNIETVATFNDAMPTGVTVSQTGRVFVNFPRWGDKVDFTVAEVKNNRSIPYPNAEINVANKDKPKDSLLSVQSVVIDALDRLWILDTGSIEFAPTINGGAKLVGVDLKTNKIFKKIVFPEDVALKTTYLNDVRFDLRRGKEGMAFITDSSLTGANAIIIVDLATGKSWRRLNNHPSTKAEDIDKFLPIVEGQPLMSRPPNAEPSPFKVGADGIAISSDGGRLYYCPLSGRTLYSVNVDALVQPASEEQVAKTVINHGDKGGASDGLESDAQNRIYVTNYEDNAILRRLPNGMYETVVHDSRLLWPDTLSLATNGYLYFTANQLHRQPNFHNGKDLRQKPYSIFRTKVDAKPVLLK
>NC_019678.1|WP_015120110.1|5153575_5153944_+|DUF1823-family-protein
MELPPLTTDTIWAILNKEIDDTTVNQLVWHYLGYGYDESTGKWDANNASEEWRSEYPEPPDFIANRPPTVKLTRSIPKENKQMLKEFLGFTGYKIGEFGPRETRRATAANWLLSYMKINGYC
>NC_019678.1|WP_015120109.1|5153008_5153302_-|acylphosphatase
MSNPTLPKQTRAHVFISGKVQGVGYRYSTMNAARNLGLNGWVKNLPDSRVEAVFEGASETVEKMIRWCHQGSDAAVVKDVQVEYSQLEGLQGFEIVS
>NC_019678.1|WP_015120108.1|5151573_5152842_+|hypothetical-protein
MYKSKKSLFQAIQQSWRFINKWFLDTPQRALLLAYEAALKIRDIEDKHFSGNKISEESNIYTANVLSYWQAELEKYLKTINFRLAEFQRSSSLLTVTDKTFLDKLKFIDEVTARYAVDKEFTTKRRIVTTQSNTQEQKEHYELDYDDTDINKMKVKPVTVKTGLFPGSITRSFKKIIKELSPRAEEKTVRDFRTSSKRTRIALKFLATLIIVPFLTYLFLKQLVIYPIVERVRTDAATDAFLNSHIEEQVLQEFKFYQQELKFEKLILQAPLLSSEIQQKQKERAIKIAEEFHHKNNSAISNVFADIISLIVFAFIIATSKREVAILQLFIDDTVYGLSDSAKAFLIILLTDMFVGFHSPHGWEVLLEGIAKHLGITPTRDVIFLFIATFPVILDTICKYWIFRYLSRISPSALATFKEMNE
>NC_019678.1|WP_015120119.1|5173666_5175754_-|AAA-family-ATPase
MTPINNIIKRELNPFDLINLKPGNFWGEKQDSDNSVDSIHQEVITEIEGLLDSVNQDNRSRSVLLLGDSGSGKSYLLGRLKRTLNKKAFFAYIGPWADSDYIWRHVLRSTVDSLIQIPEGREESQLILWLKSLSAFTRRNLKQRLFSDSIWQFMQSDRRKFIHHLKTTYSQAGLYNPDFFFGVLHDLTDPELYPIACEWLRGDDLSEESMQILKVKSCIDTEDAAKNILANFGRISIQTQPIVLCFDNLDNIPRLSDESQDFQSLFNVNTTIHNNYLKNFLVVVSIITNTWKLNSDRIQQADKVRIDKELRLKRINLEQAEALWAYRLKPLHHQVKPQPISPIFPLNRKLLQQSFPSGKTLPREVLVIGQKEYKKYKFSLVDSTVVKPIPEPEVITVPEEIKLPVPQPQIQAETIDAEFQLLWQKEYKKTQGKNQKITLFSAPDLIRMLEEALQALEVPDIKTKLLRGKYTSYSLSYRKSKKGNQIGIVWTEDSGMASFYNVMSASQKVIQSKGCETLYLIRSGSVGTSKLKGYQLYQKIFHSSKSSKHIHLKPSLASVHQLATYHNLVNSAVAQELVLSGRVIKLDELQELIRNSLIFEKCTLLQDLKVVPEPDDSEDGEDVIDLTPVNDFLFNLVKTQGFMGVPTLISQCMTQFSDAREDDVKMLIQDLCQEEKVKIIDPKAKSEDQLICLIA
>NC_019678.1|WP_015120120.1|5175820_5176678_-|hypothetical-protein
MDTNELKFLLKLLGCENYRSTLSGNAFKSFKGKNTICQNLGDREIIDFSREVAAVKILPPGQALLKLDAAEVPIEEKELRILENVAKVSGKVAPSKIKSSLKAAQKEEILRSLSDRGLIEAEIKLKKKKAEVWLTQRGIEFLRDDFSPKKGANPAISLDLLNNYLRFLRKSLKSQSQEATVTAPINNSEPVTQKSKAINDEEILQIIQKLDNELGTKDYLPIFYLREKLQPSMSRNELDQVLFKLQADDKIELSTLQEASAYTPEQIESGIKQNVGGPLFFISIF
>NC_019678.1|WP_015120121.1|5176844_5177792_-|glycosyltransferase
MPKVSICIPTFNRIDLLPFAIDSVLKQTYQDFELIVCDDGSSDGTADLMSKYEDSRIKYIRHRQNIGKSNNMLSGFDAATGDYFIKFDDDDRLTPNFIAETAAILDRDSNIDFVGTDHWIIDIDNVRDQTQTEENSRQWGREDLPGGVVNNLLQAVFVNQSFQIGATLFRRQTVVEVGFMQPNWQNCEDNDLFVRLALAGKKGYYLPKLLMEYRVHAEQQGINRAIPYLTGKQQYLQSYKFDSQELENIRLNRLRETQLLLGLRLIESGETEKGRELVNKGKSFSTAKAWTGLGLSLLPVGVRGKAFDALRKVKG
>NC_019678.1|WP_015120122.1|5178058_5178979_-|polysaccharide-pyruvyl-transferase-family-protein
MKLFYFSFPNGMSNFGDDLNPWLWEKLLPGVFDQDNKSIFVGIGTLLNDYVPKANKTAVFASGVGYSKGLPAIDESWKIYCVRGPLSAKKLGIDPQLAVTDGALLIRKVYEPSSIKKTKFAYMPHITHIIHGGNAWKDICEEAGISYIDPRWSTEEVLSAICETEVLLTEAMHGAIIADALRVPWIPVLTSTRIFPWKWQDWCLTVGVDYKPQYLMPWENVYSPGHGTVSSLRFKKNYACQAPIRLFKTLLQKESQKMANQLADIAKTSKPNLSSDTRIQQLTLQLEERLQQFQEDLTAGCFAVSN
>NC_019678.1|WP_015120123.1|5179131_5180145_-|hypothetical-protein
MQRFGIYTLANDIVYDQLVALLNSIEVNVSPDISVCIIPYNNRLDLVKQEINRRENVTLFDNIESIQRWDEFAEEVWAAHPYAKNSKLSRNTLYKSPLLRKLAALDGDFEKFVFYDADSLAMKPLEDLFSRLDEYDFIFDDWEHGKSSDVAALNIPLIEKSGLYAEEDVRPKLHCSSFFASKQGLLAPEEIERLKTLLIEKNEIEWVTRWWDDAFLFNYLTLRTECQLFNFTLSPNGEERTGNCANADPFVNIDNVLYNQQGLKPIYRLHYMNYSTNDFVRLCKGEDLNIRYRDEFLHYRFLKEPEKKPLRLKKPGLVSKANYYIKKAMNKVRLAVS
>NC_019678.1|WP_015120124.1|5180613_5181837_+|glycosyltransferase
MKILMLSSTFPYPPTRGGTQVRTFNLLKYLTKNHRVTLVTQPETGVTESEITGLRDCVDELVLFNRPHDSGTTGGILKKVQRLTKFVGKGIPPSVLNRYSVDMQNWIDNYVEAGKCDTITSEHSVNEIYIRPNFHKKIRTVVNVHSSVYGTCLNQLQNGISENTFRDRINLPLLRRYENTYCNKFSAIVATTEEDKIQLREFNSESEMMVIPNGVDLVMFPNRIADPGGHRLVFIGAMDNLANIDAVCFFCNEVLPEVQKKYPNTTFDIVGSRPVAEVLALKEKPGVNVTGKVPSMAEYLHKSTVCIVSMRTGFGIKNKTLEAMAAGIPVVGSDRGLEGLNVDGDSLELRALRANQPQEYINAISKLFENPQLRAELSYNARKLVETEFTWESAGRRYEQVCVGKGS
>NC_019678.1|WP_015120125.1|5182146_5182440_-|hypothetical-protein
MHKNTSYLLALVLAVGSALVAVPSHAQTGAENNQNIAVSSQSSISNESIVSKLKKSKAANQNEAIKISQSQSSSATANTEEPVRKNLLHSRIGWLSQ
>NC_019678.1|WP_157229439.1|5183043_5184735_-|iron-uptake-porin
MTGFQDKAVSKEQASVDLDLDFTISGKEALETKQFESKNTEQFKISQPLVESIDKTSLDENPMGQVNSVSQLRDVQPTDWAFQALQSLVERYGCIAGYPNGTYRGNRALTRYEFAAGLNACLERVNELIATAANNVVTRNDLATLQKLQEEFAAELATLRGRVDALESRAADIEAKQFSTTTKLSGITIVGIQGRGENRADTSPRDGVRDTNDPGTNINVSNFNQLYLTSQFNPRSFLVTGLLAGEGGTRPKLSNDFILGYEYDFGNDFQLSDLHFHQLLTKNLAMMVGTKGVDMVRSFRGPNRAESAANGPLSFFAQRNPILNLDFENGGIAFDWQFAKRASLQAIYSARDIGNPGKRAGLFDGNTTAAAQLLLTPARTLDVSLYYVNNYSPNGSLFSYAGDSCLTAVNCFAVPGRPLQTNGFGATVNWEISRKITLGGWAGYTNSRIPGESGDVEMTNYMVYLNFPDLFGRGNLGGVYVGQPPKIVSSDLPVGNNVPDLLNGGNGSEGGQPGTTTHIEAFYRWRLNDNISLTPGFIHIIEPGHTPDSNSVTIGILRTSFTF
>NC_019678.1|WP_015120127.1|5185127_5186627_+|hypothetical-protein
MANTSRSSKPINKGQTQPNTKVRKLRTKIKKSKNNLKHKTAPTKGIRSYSRHRQKAKKRKTLATSMFVAVTLLSSAGMVIAIGWISILFIFNPQMVSWLNPFLPEWAQITSGSKKPHTLKQIKAQIKRQKRISGKILPLENNTDESFLLPIYLDRKNCNSDCKYIVELRTYQRATDFEWQSSIEKYYHLTNNFAVTGPEEFEVIAPLVEAGIEENPGSTIALPVTEIKRFEKDAPKSGIWYYLRGNRSSGSNLTAYGYILHYNLKRRKLQTMISWTSPTGDLPQWQQVTGDGDKELVIRQTIGLEPRLRIYQTKPSEFVINPITLAEITLKPPALKDRAYKNALLIARNGLWTPSNKWLQFIKKQQKAKITPAAQAQIDLISEHSQLTKKLADTSWASPSQQVLAYLIDGRWGEALKVFEALPQNPAEIRNLLKSDTGRIESRIDAALEVNPNRSEVQAWKALIIASKQSTNQGYYWLKTQSNISKTSQTYIQKLLAQI
>NC_019678.1|WP_044291062.1|5186983_5187169_-|hypothetical-protein
MSVSSVSERKSEKSVLNSIDTCYKVDQQVKLMDLQAEVDLLLLKLQKLKQQKDVCTHEQSC

Crispr_ID: NC_019678_25

• CRISPR_ID: NC_019678_25
• CRISPR_location: 5199481-5199561
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 1 spacers

Consensus repeat of NC_019678_25

Consensus_repeat	Method
AAACTTCCTTCAAATCCGGCTCCA	CRISPRCasFinder

spacers of NC_019678_25

>25.1|5199505|33|NC_019678|CRISPRCasFinder
GTTGTTTCTTCAAATCCCAAACAATCAACTCAG

CRISPR arrays and Neighbor proteins around NC_019678_25

CRISPR arrays

The CRISPR arrays of NC_019678_25

>merge|NC_019678|25|5199481-5199561|CRISPRCasFinder
AAACTTCCTTCAAATCCGGCTCCAGTTGTTTCTTCAAATCCCAAACAATCAACTCAGAAACTTCCTTCAAATCCGGCTCCA

>NC_019678|25|22|5199481-5199561|CRISPRCasFinder
AAACTTCCTTCAAATCCGGCTCCA	GTTGTTTCTTCAAATCCCAAACAATCAACTCAG
AAACTTCCTTCAAATCCGGCTCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_044291066.1|5202813_5203269_-|diacylglycerol-kinase-family-protein	unknown	unknown	gnl|CDD|260134
NC_019678.1|WP_015120145.1|5203411_5203954_-|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl|CDD|234575
NC_019678.1|WP_015120142.1|5201368_5202139_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|316044
NC_019678.1|WP_083894080.1|5205694_5206483_-|PCRF-domain-containing-protein	unknown	unknown	gnl|CDD|234799
NC_019678.1|WP_157229306.1|5204346_5205463_-|peptide-chain-release-factor-2	unknown	unknown	gnl|CDD|234799
NC_019678.1|WP_015120134.1|5192242_5192461_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120133.1|5190862_5192137_+|CCA-tRNA-nucleotidyltransferase	unknown	unknown	gnl|CDD|223690
NC_019678.1|WP_015120141.1|5200635_5200929_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120129.1|5187574_5188669_+|threonine-synthase	unknown	unknown	gnl|CDD|236013
NC_019678.1|WP_015120146.1|5203968_5204124_-|DUF3285-domain-containing-protein	unknown	unknown	gnl|CDD|314535
NC_019678.1|WP_015120143.1|5202135_5202738_-|aminodeoxychorismate/anthranilate-synthase-component-II	unknown	unknown	gnl|CDD|235552
NC_019678.1|WP_015120131.1|5189779_5190400_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	unknown	unknown	gnl|CDD|274750
NC_019678.1|WP_015120137.1|5193769_5195398_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120147.1|5207049_5207784_-|FtsH-interacting-integral-membrane-protein	unknown	unknown	gnl|CDD|376437
NC_019678.1|WP_015120132.1|5190522_5190771_-|Ycf34-family-protein	unknown	unknown	gnl|CDD|371208
NC_019678.1|WP_015120136.1|5192943_5193204_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120138.1|5195675_5198780_-|WGR-domain-containing-protein	unknown	unknown	gnl|CDD|153427
NC_019678.1|WP_015120135.1|5192541_5192847_-|DUF3181-family-protein	unknown	unknown	gnl|CDD|371499
NC_019678.1|WP_015120148.1|5208129_5208918_+|RNA-polymerase-sigma-factor-SigF	unknown	unknown	gnl|CDD|180965
NC_019678.1|WP_015120130.1|5189147_5189492_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_044291066.1|5202813_5203269_-|diacylglycerol-kinase-family-protein	gnl|CDD|260134	cd14265, UDPK_IM_like, Integral membrane undecaprenol kinase and similar enzymes. This mostly bacterial family of homo-trimeric integral membrane enzymes, the products of the dgkA gene, catalyzes the ATP-dependent phosphorylation of undecaprenol to undecaprenyl phosphate. C55-isoprenyl (undecaprenyl) pyroposphate acts as a scaffold for the assembly of peptidoglycan components; undecaprenol kinase (UDPK) is involved in recycling undecaprenyl units for re-use in the peptidoglycan biosynthesis. UDPK does not participate in the de-novo biosynthesis of undecaprenyl phosphate. Gram-positive bacteria have a large pool of free undecaprenol, in contrast to gram-negative bacteria. UDPK may also play a role in a stress-induced pathway that affects the function of ribosomes. In Streptococcus mutans, UDPK has been shown to be required for biofilm formation, such as in the case of smooth surface dental caries. Members of the UDPK family have low activity as diacylglycerol kinases (DAGK), and many of them are annotated as DAGKs.	6.33612e-41
NC_019678.1|WP_015120145.1|5203411_5203954_-|rRNA-maturation-RNase-YbeY	gnl|CDD|234575	PRK00016, PRK00016, metal-binding heat shock protein; Provisional.	1.7597e-46
NC_019678.1|WP_015120135.1|5192541_5192847_-|DUF3181-family-protein	gnl|CDD|371499	pfam11378, DUF3181, Protein of unknown function (DUF3181). This family of proteins has no known function.	2.24228e-51
NC_019678.1|WP_083894080.1|5205694_5206483_-|PCRF-domain-containing-protein	gnl|CDD|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	7.77171e-75
NC_019678.1|WP_157229306.1|5204346_5205463_-|peptide-chain-release-factor-2	gnl|CDD|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NC_019678.1|WP_015120148.1|5208129_5208918_+|RNA-polymerase-sigma-factor-SigF	gnl|CDD|180965	PRK07408, PRK07408, RNA polymerase sigma factor SigF; Reviewed.	4.45183e-153
NC_019678.1|WP_015120129.1|5187574_5188669_+|threonine-synthase	gnl|CDD|236013	PRK07409, PRK07409, threonine synthase; Validated.	0
NC_019678.1|WP_015120146.1|5203968_5204124_-|DUF3285-domain-containing-protein	gnl|CDD|314535	pfam11688, DUF3285, Protein of unknown function (DUF3285). This family of proteins with unknown function appears to be restricted to Cyanobacteria.	3.01784e-22
NC_019678.1|WP_015120143.1|5202135_5202738_-|aminodeoxychorismate/anthranilate-synthase-component-II	gnl|CDD|235552	PRK05670, PRK05670, anthranilate synthase component II; Provisional.	2.15763e-121
NC_019678.1|WP_015120131.1|5189779_5190400_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	gnl|CDD|274750	TIGR03725, T6A_YeaZ, tRNA threonylcarbamoyl adenosine modification protein YeaZ. This family describes a protein family, YeaZ, now associated with the threonylcarbamoyl adenosine (t6A) tRNA modification. Members of this family may occur as fusions with ygjD (previously gcp) or the ribosomal protein N-acetyltransferase rimI, and is frequently encoded next to rimI. [Protein synthesis, tRNA and rRNA base modification].	8.91179e-38
NC_019678.1|WP_015120133.1|5190862_5192137_+|CCA-tRNA-nucleotidyltransferase	gnl|CDD|223690	COG0617, PcnB, tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis].	4.65632e-53
NC_019678.1|WP_015120147.1|5207049_5207784_-|FtsH-interacting-integral-membrane-protein	gnl|CDD|376437	pfam01027, Bax1-I, Inhibitor of apoptosis-promoting Bax1. Programmed cell-death involves a set of Bcl-2 family proteins, some of which inhibit apoptosis (Bcl-2 and Bcl-XL) and some of which promote it (Bax and Bak). Human Bax inhibitor, BI-1, is an evolutionarily conserved integral membrane protein containing multiple membrane-spanning segments predominantly localized to intracellular membranes. It has 6-7 membrane-spanning domains. The C termini of the mammalian BI-1 proteins are comprised of basic amino acids resembling some nuclear targeting sequences, but otherwise the predicted proteins lack motifs that suggest a function. As plant BI-1 appears to localize predominantly to the ER, we hypothesized that plant BI-1 could also regulate cell death triggered by ER stress. BI-1 appears to exert its effect through an interaction with calmodulin. The budding yeast member of this family has been found unexpectedly to encode a BH3 domain-containing protein (Ybh3p) that regulates the mitochondrial pathway of apoptosis in a phylogenetically conserved manner. Examination of the crystal structure of a bacterial member of this family shows that these proteins mediate a calcium leak across the membrane that is pH-dependent. Calcium homoeostasis balances passive calcium leak with active calcium uptake. The structure exists in a pore-closed and pore-open conformation, at pHs of 8 and 6 respectively, and the pore can be opened by intracrystalline transition; together these findings suggest that pH controls the conformational transition.	1.59322e-24
NC_019678.1|WP_015120132.1|5190522_5190771_-|Ycf34-family-protein	gnl|CDD|371208	pfam10718, Ycf34, Hypothetical chloroplast protein Ycf34. This family is of proteins annotated as hypothetical chloroplast protein YCF34. The function is not known.	5.77177e-48
NC_019678.1|WP_015120138.1|5195675_5198780_-|WGR-domain-containing-protein	gnl|CDD|153427	cd07998, WGR_DNA_ligase, WGR domain of bacterial DNA ligases. The WGR domain is found in a small family of predicted bacterial DNA ligases. It has been called WGR after the most conserved central motif of the domain. The domain typically occurs in together with an ATP-dependent DNA ligase domain, and is between 70 and 80 residues in length. It has been proposed to function as a nucleic acid binding domain.	5.63337e-31
NC_019678.1|WP_015120142.1|5201368_5202139_-|MBL-fold-metallo-hydrolase	gnl|CDD|316044	pfam13483, Lactamase_B_3, Beta-lactamase superfamily domain. This family is part of the beta-lactamase superfamily and is related to pfam00753.	2.23579e-70

Protein sequences

>NC_019678.1|WP_015120138.1|5195675_5198780_-|WGR-domain-containing-protein
MKLIKRKTLHYQKDASDKVYEVDLCEVAENKYLVNFRYGRRGANLKEGTKTTQPVALTKAEQVFDKLVAEKTRKGYVDVSASSVTTPTQPVATVDNPRIQAILNRLADDKPSSWKLERAIWKAGELKITEATPLLIDLLGTGEDLRDYCIAWALGWCCENSNNQDVIGVLTKLYQSDETADFVSGIAFEATLKICDEVKKAQLQAEAIKYLPSFFQELLKQDSSDDFTTELNAYLADCDYEDFEILEIIYEIDNEIVRPGLIDVISKAPFKPNYFQRIRHIFKVAEYRLDEEVFGILAYRFEKEKENFCHDLYRSLILDDGDYLQSSRWSNDIIEELKKPNSRIAYSNKTREYFRRRVWKTLEKLGKESNPDYIKLAVSVLLQYSERDGINNYYPNAFAYYLTFNHILYENSPRYTLWYGKSWGWKRGYKPNNPEPTVREEAFPQLWEQQPEALLKLLVESECNPVHHFAVKALRSCHKFLASINIDNIIELVNKPYEITAQFGYKLALKKYDSQNPDTNLILALANCLSKPARKQAHKWIKQNQGKFLKDSSFIAGLILSNQSETRQFAKTFLGKAVINESTAQIIIGKILVELLSFPLLNKEGLGEVNSELIKEASEILLLTFPSQLRTLNLNVINDLLTHPIVEIQELGARILLNHEIPAKDLPAHIIESLLASENESLRILGIRLFGQLPDDKLINEEKELIIAIAINPNPEIRNAIKPVINRLAAANPDFTVDIASEFIEILLTKEKHEGLHSFLVNLLKELPGWMTSISQETTLQLLKTKTSAPQELGGLLLSANYQTWIEEFTTSEIVKLSNHEIAAVRNASQQMLSQILNRLRADSQEMVAAVRMLEAKWQDSRDFAFELFTTEFTENEFTPEVLVTICDSVREEARRLGRDLLTKNFQSLDGEEYLLKFSEHPSADMQLFATNYLETYAKDDTEKLQQLAPFFISILSRVNRGSIAKKRTFEFLEAEAQKSEKAAKIVAAIMTRQSVTMAVADKSSAIQIMLKIHKKYPHLALPIEVKPVVEVRS
>NC_019678.1|WP_015120137.1|5193769_5195398_-|hypothetical-protein
MEFNYSYKGNTSVNQSANQTQMSFSPDTKRPPTYFVGELHQNVSFREAISALHDVVVSDLRFKPKDKAAYLEWRKQQDEIDWDLVAAMKQEVAAKIRPLQEELNELNKRKNQRYQPYYRAQRKYFDYLYKKDYDMWYVLDPVITVHPDEVFFECFSEDESTYGRLGASYEVFKNINEFACGTTNIDYSAALYDEFQKIRSYKTTQFQVDPSGFEVQTTNEEAYKEVKIDLPDSWVRGFLQVSSAMCLPSIQFDLHPMDIYNICLVLRRHKEKKGPRSIRYHLKPGEPVRIVFEPWDIEVVCARSPYTGNQEETIRVWGRRRLHILERLIPIAKKFTVHLLGTGMPSFYVADLGDMSFTLGLSGWTANDWSQSGNFDLMAPRADVDEWTQKLIFNGLRENWQETADSLAQKLNLSRAAVTGALSVYTQAGRVIYDLNKQVYRVRELSREPLPMDRLRFANERESSATKFLNSNRVRVLSVNDRDGKTTLQGTVNNYNPSLTIDSDERIINAECTCNWHKQNKLFKGPCEHILALRMQHARQCQ
>NC_019678.1|WP_015120136.1|5192943_5193204_-|hypothetical-protein
MPPRWPREPDRKNDPAYRKLDDRMNFAVHVATFALFNSGLWFFHNFLSTNWQWLPILTLSWLGILVSHLIYISVIADYSDTPTKST
>NC_019678.1|WP_015120135.1|5192541_5192847_-|DUF3181-family-protein
MSNNAEFMEALAAEIGENVYIDIAKWHLYLSDAKLHTVVAEQVYPLISTSKSVDEDDVIRVLQSIPIKVGGGKGEIPLLDLVPSQCQVSLVDILEKYQQEM
>NC_019678.1|WP_015120134.1|5192242_5192461_-|hypothetical-protein
MSTSKFHDGYSLADTTDELGKQALKLGLIPSFTVRFFADSREYFIAHDDKSEALTPEEAYLYFKKLVEKAEK
>NC_019678.1|WP_015120133.1|5190862_5192137_+|CCA-tRNA-nucleotidyltransferase
MYGSILSKFTPDSLPFNLELLPQPAYLVGGAVRDALLERSRDYLDLDFILPAEAVNVARKIAKYHQAGFVLLDEQRQIARVVFADATVDIAQQEGDSVEADLHRRDFTINAIAYNIHTQEIIDPLQGGADLEKGVLRMISPANLEDDPLRLMRGYRQAAQLGFTIEAETHSTIRALASHLEKVAAERIRVELGYMLANPQGTPWLIKAYEDGLLKSSFEYATSQSCAIVAEVDKVALQLTEDFPTLKGILQKNIRDTVKTTWLGIAKLACLVNSKPEIAEAELEKLTYSKAEIQSVTTALRTFPKLDAQLSLREQYFLFREAGSVFPTTAILATAYGNVVRDMSEDKPLITYASLLSRYLTPDDPVAHPTQLLSGTHIISSLNIPSSPLIGKLLTEIAVAQVEGKISTSYEAIEFARNFIQENG
>NC_019678.1|WP_015120132.1|5190522_5190771_-|Ycf34-family-protein
MCICVNCHYVDRCITYNAVETQHQQPHLTETPTFDPNEPSINVNIRTEGEVIEMEWDVVGCLSFKEEKGKWSKLRPGELVPT
>NC_019678.1|WP_015120131.1|5189779_5190400_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB
MKEYGFALHTTTPELGLAISNFADDSRSDVWKLDRNVSNLMHQYMIDFVKPQTWSDMAFIAVAKGPGGFTGTRIGVVAARTLGQQLNIPVFAVSTMAAFAWENRSDDTFIAVQMPARGGMLFCGIYQVMPDGSGLSTEIPDVVLTPEAWEEKLADLKDNYRLLKADSGLAATVASMLQLAHLDYQQGKLPHWTEALPFYGQHPVNS
>NC_019678.1|WP_015120130.1|5189147_5189492_+|hypothetical-protein
MEPVKKRPIKPKSYISFLYIYSTNWGTAGDICLIRETVAEASTSKFVGRKVKLALPRGMEKHKVEGYQVIKVAGHVGEGHPKDPGSEWEAYEGITRETAIAVLKPWGFKLVEPE
>NC_019678.1|WP_015120129.1|5187574_5188669_+|threonine-synthase
MTLSLSAVKSHRQPWQGLIEQYRQYLPVNENTPVVTLLEGNTPLIPVPSIARHIGKQVRVFVKYDGLNPTGSFKDRGMTMAVTKAKEAGAKAVICASTGNTSAAAAAYARRGGLRPFVIIPDGYVALGKLAQALVYGAEVLAIKGNFDKALEIVRDIAEEYPVTLVNSVNPYRLEGQKTGAFEVVDILGDAPDWLCIPVGNAGNITAYWMGFCQYHQDGKCGRLPQMMGFQAAGAAPLVNGEVVSNPETLATAIRIGNPASWDKAVAAAGASQGEFNSVTDEEILEAYRILAGEEGVFCEPASAASVAGLLKVKDRVPTGATVVCVLTGNGLKDPDTAIKHNKSQFTQGIEPDIKTVAKVMGFE
>NC_019678.1|WP_015120141.1|5200635_5200929_-|hypothetical-protein
MANEQKVFSILKEAKKQDLVKPSEITNPCFVSYINTANHILLEIKKKSDNKLSTEEIIKGTGLNSNTCKIYLRTLEKLNFINRAKDKESKALMWELN
>NC_019678.1|WP_015120142.1|5201368_5202139_-|MBL-fold-metallo-hydrolase
MKRRQLMGYAGAGLAGALFANLGSGLRVNAQSGGSLSIKWLGHTSFLFTGGGTTILVNPFRTIGCTAGYRPPKVTADLVLISSQLLDEGAVEGLPGSPKLMYQPGVYQFKGIKFQGIAIDHDRIGGKRFGINTAWQWKQAGVNILHLGGAAAPISLEQKILMGRPDVLLVPVGGSAKAYNAEEARKAIQILNPKLVVPTHYRTQAADNDNCDIAPLDDFLNVMGGMKVRRSNSDTISVSPGKIPENSTIQVFSYNF
>NC_019678.1|WP_015120143.1|5202135_5202738_-|aminodeoxychorismate/anthranilate-synthase-component-II
MLIVIDNYDSFTYNLVQYLGELAVNFSVAKQIKVFRNNKISLGDIRALKPDGIVISPGPGKPEDAGISLKLIEELGADYPILGVCLGHQSIGQVFGGKIVSAPELMHGKTSEVFHAGVGVFRGLDNPMTATRYHSLVIERDTIPDTLEITAWVEDGTIMGVRHRNFPHIEGVQFHPESILTNSGKQLLQNFLEKLPLISK
>NC_019678.1|WP_044291066.1|5202813_5203269_-|diacylglycerol-kinase-family-protein
MSQQISSSPKTNRLETVVSKQRDLSWAVASNLFVSFKYAWAGITYAFQTQRNFRIHVSVCALAIGLSVFLHLKPVEVAVIAVTSGLVLALELLNTAVESVVDLTVEQKYHELAKIAKDCAAGAVLVSALVALLVAAMLILPPLFELILSSL
>NC_019678.1|WP_015120145.1|5203411_5203954_-|rRNA-maturation-RNase-YbeY
MDKQLCVEVYVQDNFYQSSPTEPVENDDENLPIGVKTWENWFCKWMHMMQCDIQASSAYEIGLRLTNDSEIQTLNYQYRNQDKPTDVLAFAALEVDSPHVTEMETEDEPLYLGDIIVSVDTAQRQAIQQKHSLKTELAWLSSHGFLHLIGWDHPDEESLQRMLEKQVMLLKTLSIEVDIE
>NC_019678.1|WP_015120146.1|5203968_5204124_-|DUF3285-domain-containing-protein
MSDSSTKEDKPSYTKLAMRNMVQKGGTSLKHFALTTVGLLAVLVGLAYLTR
>NC_019678.1|WP_157229306.1|5204346_5205463_-|peptide-chain-release-factor-2
MEVLEIKREIETLSNRLGKTQDYLDLPALKAKIQDLEQIAAQPEFWEDQNKAQDTMQELNELKEHLQQYHDWHSSLEDTKAVVELLESETDESLLSEAVSNVTVLNRELDQWELQQLLSGPYDSKGALLTITAGAGGTDAQDWAEMMLRMYTRWGESHGYKVAITDKSDGDEAGIKSVTLEITGRYAYGYLRSEMGTHRLVRISPFNANGKRQTSFAGVEIMPQIDDNVELDIPDKDLEITTSRAGGKGGQNVNKVETAVRIVHIPTNIAVRCTEERSQLQNKEKALARLKAKLLVVAQEQHAQEIAEIRGDMVEASWGNQIRNYVFHPYQMVKDLRTNIETTAITDVMNGELDSFIQAYLRQENQVTENG
>NC_019678.1|WP_083894080.1|5205694_5206483_-|PCRF-domain-containing-protein
MRTTYEFLSSKLKHVEILNLLNQPFDDKGAFVTITACDRNIDCQDWVEMLQRMYAHWCDNHDCKLRFLDESIGEFCGFNYVTLEISGKYAYGYLKSEQGIHQLKRISPFRKKPAIKTSFAKLEVAPIVDESMDFEIPQRDLEVLRGKHTYMRGPSPLAKVTHIPTGISVTSTEKRNHLANLEKALVCVKSKLFALMQIQGVALKDVKKPSPKTTLDNPIREYIFHPYQKVKDSRTNVETVEIEEVMKGNLDLFTKAYLKQMH
>NC_019678.1|WP_015120147.1|5207049_5207784_-|FtsH-interacting-integral-membrane-protein
MSNTSNFRNAIRDAKNQALVGPNVIANALPYVGGGLVLTALGTYGGLGVIRNNPQLFYPTFFGALIVSLILFFVAQNVASKGNKQVALPLLAAYSLLSGYTLSGLVFVALRTQGVGIEGIGIAALGCGVTFIAARQIGSNLSDSDGMALTKTVRLGVIALIAVMILQLGLSLFGVYTPGWLEIGISGLGVCLFAGAAVVDFYVLPRTYQDDEYLPAALSMYLTYINLFVFILRLLIAISGGGRD
>NC_019678.1|WP_015120148.1|5208129_5208918_+|RNA-polymerase-sigma-factor-SigF
MAVIQSSLRSDGMELLCLYHQNPSIKLRNRLVKLHSGLVRKMAHKFSHQCNEPYEDLEQIGYFGLIRAIERFDPTQGYAFSSFAVPYIRGEMLHFLRDRSTLLKIPRRWQELYNEGQKIRKELAHILGRQPKDLEIARELKVSVQEWQETKLAVQNRMPLSLDATVVNYIDCQITLGEALPCPQTAAQQHLEEERQQLHGAMGMLEDKPRMAVELVFLKEFSRKDAAKKIGTSPMTVTRYLQKGIDDLMGLMQQPQAVATVT

Crispr_ID: NC_019678_26

• CRISPR_ID: NC_019678_26
• CRISPR_location: 6181145-6188351
• Repeat_type: A:N
• Spacer_info: 100 spacers
• Cas_protein_info: cas2,cas1,RT,WYL

Consensus repeat of NC_019678_26

Consensus_repeat	Method
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	PILER-CR
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CRISPRCasFinder
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CRT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	PILER-CR

spacers of NC_019678_26

>26.1|6181181|32|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTGGGGGAAGTTTGCATATTAACTCGTTACCT
>26.2|6181249|38|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTTTACCAATGAAGTTTCCAGTGATAGCAATTATGTTA
>26.3|6181323|38|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTCATCGTCTCCACCAGTTTCACGTATAACAGAACTTT
>26.4|6181397|36|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GCTAAGCATGGCACTTAGCCTATAAACTGCTTGATC
>26.5|6181469|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTGGTTAGACATTTTAGCAATCCTTTAAAAATAA
>26.6|6181539|37|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GTGTAGTTCGGTAAAAACCTAAAGGTTCTTCACGGTG
>26.7|6181612|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TCTACGAGCAAGCGGTTTGCTGTTGGGGTAGGCA
>26.8|6181682|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TGCGGGTGTCAACGGTTTCACCACGGACACCATG
>26.9|6181752|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTACTTGCTGGTTTAAACAATAAGCTAAGACAA
>26.10|6181821|37|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TCTCCGTCTGCGTTTTTTGACTTTCCGCAAGCCACAA
>26.11|6181894|36|NC_019678|PILER-CR,CRISPRCasFinder,CRT
ATTTTTTAGAAACGCAAAAAATTACTTCCTAAAAGC
>26.12|6181966|38|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTTTAGGTTATTTTTGTAATAAACCATAGTAGATCTAG
>26.13|6182040|32|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TGAAGTAAGTCACAAACTAACAACAAATCGTT
>26.14|6182108|37|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AATTACTTCTCCACAAGCAAGGGCTTGAGAAGGTTGA
>26.15|6182181|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TCTGTGATATTCTCTTCTTTCTCTAACCACTTTTA
>26.16|6182252|40|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AAATGTGCTTTAAATGCAGTTTCAAGCGATTCAAAAGCAT
>26.17|6182328|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
ATTAATTGCTTTTAATTTCACTTGTTGTTTCCTTT
>26.18|6182399|39|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CTTGAAGAGAAAGAATAGTTTTTTCTTTTTGTTCAGCTT
>26.19|6182474|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GTTTGGGCGAGTAAGTGAAACTTTTTTTCCCGCAA
>26.20|6182545|36|NC_019678|PILER-CR,CRISPRCasFinder,CRT
ATAAGCTAAGACAATAATTGCGCCTTCGTGTCCCCC
>26.21|6182617|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TATAAACTGTGTTTTCGTTAAAACCCCCAACAGCA
>26.22|6182688|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AAAAACAGTGTCAGCATTGACTCTACCAGCTTTC
>26.23|6182758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTTACATCTTGAATTATTTTCTTTATTCCTAAT
>26.24|6182827|32|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TGTGTAGTCATGATGACTTACCTCAATTTAAG
>26.25|6182895|37|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTCCATGGTGATGATACCATTACAAGCACGGGCAACA
>26.26|6182968|38|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TAACAAGGGATTATGCGATTCAGATCGTAAAAAAAATA
>26.27|6183042|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CTGGAACTTTGCGTCCACAGATTAGACCTAGTTC
>26.28|6183112|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CATACATTGTTGCCCGTGCTTGTAATGGTATCATC
>26.29|6183183|36|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GGAAACCCAAATTCCTGCTCACCAAGGGGGGCATGA
>26.30|6183255|38|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTTCAAATGACCGAATACGAACAACTTTTGCAGGTGAA
>26.31|6183329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CATTCCATTACTGGATTAGCGACAGCAGGGTTCAC
>26.32|6183400|31|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CATAGATACGGCATTAAGAGCTATAATTCTT
>26.33|6183467|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GATAGAGCAATAAACCCTAAAGCAACACTGACTAT
>26.34|6183538|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTATATATTTTGTAGCGGTTTTAAATTCTGAAG
>26.35|6183607|37|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTGGCTACATAACTTTGATTTTCTTCTATGTATTCTT
>26.36|6183680|37|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GTTAGTAAATTACTTTACAAGAAAAATCTTGTAATTG
>26.37|6183753|37|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TCTACTTTGTTAGCGAAACCTGTTGCAAACCTAGCAA
>26.38|6183826|40|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTTTTCACCAAGCTCTGTTTTCAAAACTTGTTGAACTTTA
>26.39|6183902|36|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AATGATATGTATCCCAATTGAAGCACGTTTTATTAT
>26.40|6183974|37|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTTAAAATATTCACTATGTAAAAAGAAATAAACCTAT
>26.41|6184047|32|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CACCATTATTTGTTTGAGTGGTAGGGGGATGA
>26.42|6184115|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GCTAGGGCCCGGCTGGGGAGAGGGCTCCCTATTAG
>26.43|6184186|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTATTACCTTCATGCTTGGAAAAAATTCTAGACAC
>26.44|6184257|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
ACTAACCCACACAATGAGGCTGAATGAATTTTTT
>26.45|6184327|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AGCTGTAGCAATCTTTAAGTAAATCTTAGAAAA
>26.46|6184396|38|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CATCGGAAACATCTTTATTACCTTCATGCTTGGAAAAA
>26.47|6184470|38|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AAGCTTCCAAGAGCGATTTTGAGACTTGCCAGATGCAA
>26.48|6184544|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TCGACTGAAAGCGATTGGGCGAAATTTTTTGCTA
>26.49|6184614|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CTGAATGGCATGATGGTAGTTACTTTTGTCAATT
>26.50|6184684|38|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TGTAACAGATCCAAGAGCAGCAAAACAGGCACCAGCAA
>26.51|6184758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTTAAAAATTAAAATATTACTTAAAATAATTTT
>26.52|6184827|38|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GATTGGCATCGCACTTGCAATTTTCTCCGTATAGCCTA
>26.53|6184901|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GATATATAACTCCCACGTTCAGATGAACGTCTCT
>26.54|6184971|38|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTTGGTTAAAAGAGTCGAAATAAACAAATATTACGTTT
>26.55|6185045|38|NC_019678|CRISPRCasFinder,CRT
TGGCTATAACTATGGTGGTAAGCCACAGGCAATACGCG
>26.56|6185119|33|NC_019678|CRISPRCasFinder,CRT
ATTTTTCTCCACAAAATTATAGAAAGAAAAAAT
>26.57|6185188|37|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TTGATAAGAGAAAGCAAGAAGTTGCAACAATAGCAAC
>26.58|6185261|37|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AGTAAGTCCACCAATCTCAAAAACTGTAGTTCCATTT
>26.59|6185334|36|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AAATATCTCCTAATTTGAGAAATTTCGGTTGCGGTT
>26.60|6185406|37|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TTTAATCATTCGACTACTCATTCTAACCCGAACAAAA
>26.61|6185479|36|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AAACTTTACTAGATTGTGGCATAATTTTACCTACCT
>26.62|6185551|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AACTAGGAGAAAAACTTGTTTCAGCAACTAAAA
>26.63|6185620|36|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TAGCTATTGCGGATTGCAGCAGATAACTTGATAACT
>26.64|6185692|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TTAAAGAAGTTGTGTAGCTTGCCCGTATATCAA
>26.65|6185761|34|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AATTATACTAGCTTCTGAACTACCAGACATTTCA
>26.66|6185831|41|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AACTTGATTAACGTCAAATTTGTTAAGAGTTTCTTCAATCC
>26.67|6185908|36|NC_019678|CRISPRCasFinder,CRT,PILER-CR
ACCTGCACACTTGCCTTTAGTTCTAACATCAGAAGA
>26.68|6185980|38|NC_019678|CRISPRCasFinder,CRT,PILER-CR
ACTATTAGAACCATTGTGTTTTACAAACACAGTGTCTT
>26.69|6186054|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TTTAGGAGTTAATCTGATTAGTCTACCAACGTC
>26.70|6186123|31|NC_019678|CRISPRCasFinder,CRT,PILER-CR
GTTAGTGGTTTTTTGCGAACCTGCAAATCCG
>26.71|6186190|41|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AATGCTGCAACTAACGTTAAAACCACAAATACCAAAAAATA
>26.72|6186267|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR
GTTCTTCCTCCATCTCGCACTTAGAAGGGTGTG
>26.73|6186336|37|NC_019678|CRISPRCasFinder,CRT,PILER-CR
CATCTAAATAAGAATAATACAACTACCACATCTCGCA
>26.74|6186409|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR
GATTGATCTTCATAGTCAAAATTTTCTTCTTTC
>26.75|6186478|38|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TTTAATGTATTCTGCAGCAGAAAGAAAAAACACTCTAT
>26.76|6186552|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TCTCACTTCTTGCAATCTTTCAACTGCTTGATTAT
>26.77|6186623|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AATTCATATCAGTAATCGTTTGATTTCTGATATAT
>26.78|6186694|40|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TTTCCAATGCTAGAGTTACCAGAATTATTAAGTTCGGATT
>26.79|6186770|39|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AAGAAGGGAAACCATGGTTTCCATGTATTTAGCGGAATA
>26.80|6186845|34|NC_019678|CRISPRCasFinder,CRT,PILER-CR
GCTTCACACTACGTTTCATTTCTAAATCGTATAA
>26.81|6186915|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR
GAGACCTCCGAAGATGCTGTCATTGCCGTTTCCAC
>26.82|6186986|39|NC_019678|CRISPRCasFinder,CRT,PILER-CR
CACATCAAATGTGCCGCCTAGCGCAAGTTCCTGCTGCCA
>26.83|6187061|38|NC_019678|CRISPRCasFinder,CRT,PILER-CR
GATTGGTTAGTCAATGCACACAACTTAATGAATGCAAT
>26.84|6187135|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR
ATTCAGATGAATCTACGACTGTGCTTCCTTGAC
>26.85|6187204|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TTTAGGAAACAAATAACCCCCCAAAAAAAAAGA
>26.86|6187273|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR
ACGTATTCTCGGAAATATAGTGACGACCTGCTAAA
>26.87|6187344|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR
CTATGATGAGGAAGATCCACAAAGGATAATCTC
>26.88|6187413|37|NC_019678|CRISPRCasFinder,CRT,PILER-CR
ACCTGATCCTCCGTGCAGAAGGTCTTCTTGGAAGCCT
>26.89|6187486|38|NC_019678|CRISPRCasFinder,CRT,PILER-CR
CCTTTATCTCATTTGCAAGAAAATTCTGAACATTTGGA
>26.90|6187560|34|NC_019678|CRISPRCasFinder,CRT,PILER-CR
CTACAAAAGTAACCGCAACTAATGTTCCAACAAA
>26.91|6187630|36|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TTTAAGACCATCTAGGAAGAAATCTGGAACGTATCC
>26.92|6187702|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TTTTTATATATGCAGAAAATGCGGGCTCTCCTACA
>26.93|6187773|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TCTCAACTCTTGCAAGCCTTTCATCAAGCTCTTTT
>26.94|6187844|41|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TTTTTGATGGTTGAACACTTTTTAGGAACTTCATATTTATA
>26.95|6187921|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR
CGTATTCATCAGATACAATGTTAAAATTATCAAGA
>26.96|6187992|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR
CTTGAGCTTGCGTGTGATCGTTTCCCATCTTCAGT
>26.97|6188063|38|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TCTGCGGGTGCAGCTGCAAAAAATGTGCCTAAAATCAG
>26.98|6188137|34|NC_019678|CRISPRCasFinder,CRT,PILER-CR
ATTGTATGTTCATTAGAAACTTTCACGTCTCTGT
>26.99|6188207|38|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AGAATTTGATCATGTCTAACCAAAAGAATGTATTCATC
>26.100|6188281|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR
CTACCCAGTAAGGATAAATGCCAACGTTCTTCATC

CRISPR arrays and Neighbor proteins around NC_019678_26

CRISPR arrays

The CRISPR arrays of NC_019678_26

>merge|NC_019678|26|6181145-6188351|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTGGGGGAAGTTTGCATATTAACTCGTTACCTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTTACCAATGAAGTTTCCAGTGATAGCAATTATGTTACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTCATCGTCTCCACCAGTTTCACGTATAACAGAACTTTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACGCTAAGCATGGCACTTAGCCTATAAACTGCTTGATCCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTGGTTAGACATTTTAGCAATCCTTTAAAAATAACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACGTGTAGTTCGGTAAAAACCTAAAGGTTCTTCACGGTGCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTCTACGAGCAAGCGGTTTGCTGTTGGGGTAGGCACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTGCGGGTGTCAACGGTTTCACCACGGACACCATGCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTACTTGCTGGTTTAAACAATAAGCTAAGACAACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTCTCCGTCTGCGTTTTTTGACTTTCCGCAAGCCACAACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACATTTTTTAGAAACGCAAAAAATTACTTCCTAAAAGCCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTTAGGTTATTTTTGTAATAAACCATAGTAGATCTAGCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTGAAGTAAGTCACAAACTAACAACAAATCGTTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACAATTACTTCTCCACAAGCAAGGGCTTGAGAAGGTTGACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTCTGTGATATTCTCTTCTTTCTCTAACCACTTTTACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACAAATGTGCTTTAAATGCAGTTTCAAGCGATTCAAAAGCATCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACATTAATTGCTTTTAATTTCACTTGTTGTTTCCTTTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACCTTGAAGAGAAAGAATAGTTTTTTCTTTTTGTTCAGCTTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACGTTTGGGCGAGTAAGTGAAACTTTTTTTCCCGCAACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACATAAGCTAAGACAATAATTGCGCCTTCGTGTCCCCCCCCCAGCGATTGGGTTAATTCGGATTAGTTGGAAACTATAAACTGTGTTTTCGTTAAAACCCCCAACAGCACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACAAAAACAGTGTCAGCATTGACTCTACCAGCTTTCCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTACATCTTGAATTATTTTCTTTATTCCTAATCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTGTGTAGTCATGATGACTTACCTCAATTTAAGCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTCCATGGTGATGATACCATTACAAGCACGGGCAACACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTAACAAGGGATTATGCGATTCAGATCGTAAAAAAAATACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACCTGGAACTTTGCGTCCACAGATTAGACCTAGTTCCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACCATACATTGTTGCCCGTGCTTGTAATGGTATCATCCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACGGAAACCCAAATTCCTGCTCACCAAGGGGGGCATGACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTCAAATGACCGAATACGAACAACTTTTGCAGGTGAACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACCATTCCATTACTGGATTAGCGACAGCAGGGTTCACCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACCATAGATACGGCATTAAGAGCTATAATTCTTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACGATAGAGCAATAAACCCTAAAGCAACACTGACTATCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTATATATTTTGTAGCGGTTTTAAATTCTGAAGCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTGGCTACATAACTTTGATTTTCTTCTATGTATTCTTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACGTTAGTAAATTACTTTACAAGAAAAATCTTGTAATTGCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTCTACTTTGTTAGCGAAACCTGTTGCAAACCTAGCAACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTTTCACCAAGCTCTGTTTTCAAAACTTGTTGAACTTTACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACAATGATATGTATCCCAATTGAAGCACGTTTTATTATCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTAAAATATTCACTATGTAAAAAGAAATAAACCTATCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACCACCATTATTTGTTTGAGTGGTAGGGGGATGACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACGCTAGGGCCCGGCTGGGGAGAGGGCTCCCTATTAGCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTATTACCTTCATGCTTGGAAAAAATTCTAGACACCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACACTAACCCACACAATGAGGCTGAATGAATTTTTTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACAGCTGTAGCAATCTTTAAGTAAATCTTAGAAAACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACCATCGGAAACATCTTTATTACCTTCATGCTTGGAAAAACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACAAGCTTCCAAGAGCGATTTTGAGACTTGCCAGATGCAACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTCGACTGAAAGCGATTGGGCGAAATTTTTTGCTACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACCTGAATGGCATGATGGTAGTTACTTTTGTCAATTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTGTAACAGATCCAAGAGCAGCAAAACAGGCACCAGCAACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTAAAAATTAAAATATTACTTAAAATAATTTTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACGATTGGCATCGCACTTGCAATTTTCTCCGTATAGCCTACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACGATATATAACTCCCACGTTCAGATGAACGTCTCTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTGGTTAAAAGAGTCGAAATAAACAAATATTACGTTTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTGGCTATAACTATGGTGGTAAGCCACAGGCAATACGCGCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACATTTTTCTCCACAAAATTATAGAAAGAAAAAATCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTGATAAGAGAAAGCAAGAAGTTGCAACAATAGCAACCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACAGTAAGTCCACCAATCTCAAAAACTGTAGTTCCATTTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACAAATATCTCCTAATTTGAGAAATTTCGGTTGCGGTTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTAATCATTCGACTACTCATTCTAACCCGAACAAAACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACAAACTTTACTAGATTGTGGCATAATTTTACCTACCTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACAACTAGGAGAAAAACTTGTTTCAGCAACTAAAACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTAGCTATTGCGGATTGCAGCAGATAACTTGATAACTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTAAAGAAGTTGTGTAGCTTGCCCGTATATCAACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACAATTATACTAGCTTCTGAACTACCAGACATTTCACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACAACTTGATTAACGTCAAATTTGTTAAGAGTTTCTTCAATCCCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACACCTGCACACTTGCCTTTAGTTCTAACATCAGAAGACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACACTATTAGAACCATTGTGTTTTACAAACACAGTGTCTTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTAGGAGTTAATCTGATTAGTCTACCAACGTCCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACGTTAGTGGTTTTTTGCGAACCTGCAAATCCGCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACAATGCTGCAACTAACGTTAAAACCACAAATACCAAAAAATACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACGTTCTTCCTCCATCTCGCACTTAGAAGGGTGTGCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACCATCTAAATAAGAATAATACAACTACCACATCTCGCACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACGATTGATCTTCATAGTCAAAATTTTCTTCTTTCCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTAATGTATTCTGCAGCAGAAAGAAAAAACACTCTATCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTCTCACTTCTTGCAATCTTTCAACTGCTTGATTATCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACAATTCATATCAGTAATCGTTTGATTTCTGATATATCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTCCAATGCTAGAGTTACCAGAATTATTAAGTTCGGATTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACAAGAAGGGAAACCATGGTTTCCATGTATTTAGCGGAATACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACGCTTCACACTACGTTTCATTTCTAAATCGTATAACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACGAGACCTCCGAAGATGCTGTCATTGCCGTTTCCACCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACCACATCAAATGTGCCGCCTAGCGCAAGTTCCTGCTGCCACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACGATTGGTTAGTCAATGCACACAACTTAATGAATGCAATCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACATTCAGATGAATCTACGACTGTGCTTCCTTGACCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTAGGAAACAAATAACCCCCCAAAAAAAAAGACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACACGTATTCTCGGAAATATAGTGACGACCTGCTAAACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACCTATGATGAGGAAGATCCACAAAGGATAATCTCCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACACCTGATCCTCCGTGCAGAAGGTCTTCTTGGAAGCCTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACCCTTTATCTCATTTGCAAGAAAATTCTGAACATTTGGACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACCTACAAAAGTAACCGCAACTAATGTTCCAACAAACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTAAGACCATCTAGGAAGAAATCTGGAACGTATCCCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTTTATATATGCAGAAAATGCGGGCTCTCCTACACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTCTCAACTCTTGCAAGCCTTTCATCAAGCTCTTTTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTTTGATGGTTGAACACTTTTTAGGAACTTCATATTTATACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACCGTATTCATCAGATACAATGTTAAAATTATCAAGACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACCTTGAGCTTGCGTGTGATCGTTTCCCATCTTCAGTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTCTGCGGGTGCAGCTGCAAAAAATGTGCCTAAAATCAGCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACATTGTATGTTCATTAGAAACTTTCACGTCTCTGTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACAGAATTTGATCATGTCTAACCAAAAGAATGTATTCATCCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACCTACCCAGTAAGGATAAATGCCAACGTTCTTCATCCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC

>NC_019678|26|9|6181145-6185044|PILER-CR
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTGGGGGAAGTTTGCATATTAACTCGTTACCT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTACCAATGAAGTTTCCAGTGATAGCAATTATGTTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTCATCGTCTCCACCAGTTTCACGTATAACAGAACTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GCTAAGCATGGCACTTAGCCTATAAACTGCTTGATC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTGGTTAGACATTTTAGCAATCCTTTAAAAATAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTGTAGTTCGGTAAAAACCTAAAGGTTCTTCACGGTG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTACGAGCAAGCGGTTTGCTGTTGGGGTAGGCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGCGGGTGTCAACGGTTTCACCACGGACACCATG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTACTTGCTGGTTTAAACAATAAGCTAAGACAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTCCGTCTGCGTTTTTTGACTTTCCGCAAGCCACAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTTTTTAGAAACGCAAAAAATTACTTCCTAAAAGC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTAGGTTATTTTTGTAATAAACCATAGTAGATCTAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGAAGTAAGTCACAAACTAACAACAAATCGTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATTACTTCTCCACAAGCAAGGGCTTGAGAAGGTTGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTGTGATATTCTCTTCTTTCTCTAACCACTTTTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAATGTGCTTTAAATGCAGTTTCAAGCGATTCAAAAGCAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTAATTGCTTTTAATTTCACTTGTTGTTTCCTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTTGAAGAGAAAGAATAGTTTTTTCTTTTTGTTCAGCTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTTTGGGCGAGTAAGTGAAACTTTTTTTCCCGCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATAAGCTAAGACAATAATTGCGCCTTCGTGTCCCCC
CCCCAGCGATTGGGTTAATTCGGATTAGTTGGAAAC	TATAAACTGTGTTTTCGTTAAAACCCCCAACAGCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAAAACAGTGTCAGCATTGACTCTACCAGCTTTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTACATCTTGAATTATTTTCTTTATTCCTAAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGTGTAGTCATGATGACTTACCTCAATTTAAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTCCATGGTGATGATACCATTACAAGCACGGGCAACA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TAACAAGGGATTATGCGATTCAGATCGTAAAAAAAATA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTGGAACTTTGCGTCCACAGATTAGACCTAGTTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATACATTGTTGCCCGTGCTTGTAATGGTATCATC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GGAAACCCAAATTCCTGCTCACCAAGGGGGGCATGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTCAAATGACCGAATACGAACAACTTTTGCAGGTGAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATTCCATTACTGGATTAGCGACAGCAGGGTTCAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATAGATACGGCATTAAGAGCTATAATTCTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATAGAGCAATAAACCCTAAAGCAACACTGACTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTATATATTTTGTAGCGGTTTTAAATTCTGAAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTGGCTACATAACTTTGATTTTCTTCTATGTATTCTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTTAGTAAATTACTTTACAAGAAAAATCTTGTAATTG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTACTTTGTTAGCGAAACCTGTTGCAAACCTAGCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTTCACCAAGCTCTGTTTTCAAAACTTGTTGAACTTTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATGATATGTATCCCAATTGAAGCACGTTTTATTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAAAATATTCACTATGTAAAAAGAAATAAACCTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CACCATTATTTGTTTGAGTGGTAGGGGGATGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GCTAGGGCCCGGCTGGGGAGAGGGCTCCCTATTAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTATTACCTTCATGCTTGGAAAAAATTCTAGACAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACTAACCCACACAATGAGGCTGAATGAATTTTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AGCTGTAGCAATCTTTAAGTAAATCTTAGAAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATCGGAAACATCTTTATTACCTTCATGCTTGGAAAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAGCTTCCAAGAGCGATTTTGAGACTTGCCAGATGCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCGACTGAAAGCGATTGGGCGAAATTTTTTGCTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTGAATGGCATGATGGTAGTTACTTTTGTCAATT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGTAACAGATCCAAGAGCAGCAAAACAGGCACCAGCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAAAAATTAAAATATTACTTAAAATAATTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATTGGCATCGCACTTGCAATTTTCTCCGTATAGCCTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATATATAACTCCCACGTTCAGATGAACGTCTCT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTGGTTAAAAGAGTCGAAATAAACAAATATTACGTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTGGCTATAACTATGGTGGTAAGCCACAGGCAATACGCGCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACATTTTTCTCCACAAAATTATAGAAAGAAAAAATCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTGATAAGAGAAAGCAAGAAGTTGCAACAATAGCAAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AGTAAGTCCACCAATCTCAAAAACTGTAGTTCCATTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAATATCTCCTAATTTGAGAAATTTCGGTTGCGGTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAATCATTCGACTACTCATTCTAACCCGAACAAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAACTTTACTAGATTGTGGCATAATTTTACCTACCT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AACTAGGAGAAAAACTTGTTTCAGCAACTAAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TAGCTATTGCGGATTGCAGCAGATAACTTGATAACT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTAAAGAAGTTGTGTAGCTTGCCCGTATATCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATTATACTAGCTTCTGAACTACCAGACATTTCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AACTTGATTAACGTCAAATTTGTTAAGAGTTTCTTCAATCC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACCTGCACACTTGCCTTTAGTTCTAACATCAGAAGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACTATTAGAACCATTGTGTTTTACAAACACAGTGTCTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAGGAGTTAATCTGATTAGTCTACCAACGTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTTAGTGGTTTTTTGCGAACCTGCAAATCCG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATGCTGCAACTAACGTTAAAACCACAAATACCAAAAAATA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTTCTTCCTCCATCTCGCACTTAGAAGGGTGTG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATCTAAATAAGAATAATACAACTACCACATCTCGCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATTGATCTTCATAGTCAAAATTTTCTTCTTTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAATGTATTCTGCAGCAGAAAGAAAAAACACTCTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTCACTTCTTGCAATCTTTCAACTGCTTGATTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATTCATATCAGTAATCGTTTGATTTCTGATATAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTCCAATGCTAGAGTTACCAGAATTATTAAGTTCGGATT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAGAAGGGAAACCATGGTTTCCATGTATTTAGCGGAATA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GCTTCACACTACGTTTCATTTCTAAATCGTATAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GAGACCTCCGAAGATGCTGTCATTGCCGTTTCCAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CACATCAAATGTGCCGCCTAGCGCAAGTTCCTGCTGCCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATTGGTTAGTCAATGCACACAACTTAATGAATGCAAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTCAGATGAATCTACGACTGTGCTTCCTTGAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAGGAAACAAATAACCCCCCAAAAAAAAAGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACGTATTCTCGGAAATATAGTGACGACCTGCTAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTATGATGAGGAAGATCCACAAAGGATAATCTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACCTGATCCTCCGTGCAGAAGGTCTTCTTGGAAGCCT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CCTTTATCTCATTTGCAAGAAAATTCTGAACATTTGGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTACAAAAGTAACCGCAACTAATGTTCCAACAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAAGACCATCTAGGAAGAAATCTGGAACGTATCC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTTATATATGCAGAAAATGCGGGCTCTCCTACA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTCAACTCTTGCAAGCCTTTCATCAAGCTCTTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTTGATGGTTGAACACTTTTTAGGAACTTCATATTTATA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CGTATTCATCAGATACAATGTTAAAATTATCAAGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTTGAGCTTGCGTGTGATCGTTTCCCATCTTCAGT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTGCGGGTGCAGCTGCAAAAAATGTGCCTAAAATCAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTGTATGTTCATTAGAAACTTTCACGTCTCTGT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AGAATTTGATCATGTCTAACCAAAAGAATGTATTCATC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTACCCAGTAAGGATAAATGCCAACGTTCTTCATC


>NC_019678|26|23|6181145-6188351|CRISPRCasFinder
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTGGGGGAAGTTTGCATATTAACTCGTTACCT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTACCAATGAAGTTTCCAGTGATAGCAATTATGTTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTCATCGTCTCCACCAGTTTCACGTATAACAGAACTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GCTAAGCATGGCACTTAGCCTATAAACTGCTTGATC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTGGTTAGACATTTTAGCAATCCTTTAAAAATAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTGTAGTTCGGTAAAAACCTAAAGGTTCTTCACGGTG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTACGAGCAAGCGGTTTGCTGTTGGGGTAGGCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGCGGGTGTCAACGGTTTCACCACGGACACCATG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTACTTGCTGGTTTAAACAATAAGCTAAGACAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTCCGTCTGCGTTTTTTGACTTTCCGCAAGCCACAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTTTTTAGAAACGCAAAAAATTACTTCCTAAAAGC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTAGGTTATTTTTGTAATAAACCATAGTAGATCTAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGAAGTAAGTCACAAACTAACAACAAATCGTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATTACTTCTCCACAAGCAAGGGCTTGAGAAGGTTGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTGTGATATTCTCTTCTTTCTCTAACCACTTTTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAATGTGCTTTAAATGCAGTTTCAAGCGATTCAAAAGCAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTAATTGCTTTTAATTTCACTTGTTGTTTCCTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTTGAAGAGAAAGAATAGTTTTTTCTTTTTGTTCAGCTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTTTGGGCGAGTAAGTGAAACTTTTTTTCCCGCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATAAGCTAAGACAATAATTGCGCCTTCGTGTCCCCC
CCCCAGCGATTGGGTTAATTCGGATTAGTTGGAAAC	TATAAACTGTGTTTTCGTTAAAACCCCCAACAGCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAAAACAGTGTCAGCATTGACTCTACCAGCTTTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTACATCTTGAATTATTTTCTTTATTCCTAAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGTGTAGTCATGATGACTTACCTCAATTTAAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTCCATGGTGATGATACCATTACAAGCACGGGCAACA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TAACAAGGGATTATGCGATTCAGATCGTAAAAAAAATA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTGGAACTTTGCGTCCACAGATTAGACCTAGTTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATACATTGTTGCCCGTGCTTGTAATGGTATCATC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GGAAACCCAAATTCCTGCTCACCAAGGGGGGCATGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTCAAATGACCGAATACGAACAACTTTTGCAGGTGAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATTCCATTACTGGATTAGCGACAGCAGGGTTCAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATAGATACGGCATTAAGAGCTATAATTCTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATAGAGCAATAAACCCTAAAGCAACACTGACTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTATATATTTTGTAGCGGTTTTAAATTCTGAAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTGGCTACATAACTTTGATTTTCTTCTATGTATTCTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTTAGTAAATTACTTTACAAGAAAAATCTTGTAATTG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTACTTTGTTAGCGAAACCTGTTGCAAACCTAGCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTTCACCAAGCTCTGTTTTCAAAACTTGTTGAACTTTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATGATATGTATCCCAATTGAAGCACGTTTTATTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAAAATATTCACTATGTAAAAAGAAATAAACCTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CACCATTATTTGTTTGAGTGGTAGGGGGATGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GCTAGGGCCCGGCTGGGGAGAGGGCTCCCTATTAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTATTACCTTCATGCTTGGAAAAAATTCTAGACAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACTAACCCACACAATGAGGCTGAATGAATTTTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AGCTGTAGCAATCTTTAAGTAAATCTTAGAAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATCGGAAACATCTTTATTACCTTCATGCTTGGAAAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAGCTTCCAAGAGCGATTTTGAGACTTGCCAGATGCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCGACTGAAAGCGATTGGGCGAAATTTTTTGCTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTGAATGGCATGATGGTAGTTACTTTTGTCAATT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGTAACAGATCCAAGAGCAGCAAAACAGGCACCAGCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAAAAATTAAAATATTACTTAAAATAATTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATTGGCATCGCACTTGCAATTTTCTCCGTATAGCCTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATATATAACTCCCACGTTCAGATGAACGTCTCT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTGGTTAAAAGAGTCGAAATAAACAAATATTACGTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGGCTATAACTATGGTGGTAAGCCACAGGCAATACGCG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTTTTCTCCACAAAATTATAGAAAGAAAAAAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTGATAAGAGAAAGCAAGAAGTTGCAACAATAGCAAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AGTAAGTCCACCAATCTCAAAAACTGTAGTTCCATTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAATATCTCCTAATTTGAGAAATTTCGGTTGCGGTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAATCATTCGACTACTCATTCTAACCCGAACAAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAACTTTACTAGATTGTGGCATAATTTTACCTACCT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AACTAGGAGAAAAACTTGTTTCAGCAACTAAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TAGCTATTGCGGATTGCAGCAGATAACTTGATAACT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTAAAGAAGTTGTGTAGCTTGCCCGTATATCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATTATACTAGCTTCTGAACTACCAGACATTTCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AACTTGATTAACGTCAAATTTGTTAAGAGTTTCTTCAATCC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACCTGCACACTTGCCTTTAGTTCTAACATCAGAAGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACTATTAGAACCATTGTGTTTTACAAACACAGTGTCTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAGGAGTTAATCTGATTAGTCTACCAACGTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTTAGTGGTTTTTTGCGAACCTGCAAATCCG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATGCTGCAACTAACGTTAAAACCACAAATACCAAAAAATA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTTCTTCCTCCATCTCGCACTTAGAAGGGTGTG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATCTAAATAAGAATAATACAACTACCACATCTCGCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATTGATCTTCATAGTCAAAATTTTCTTCTTTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAATGTATTCTGCAGCAGAAAGAAAAAACACTCTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTCACTTCTTGCAATCTTTCAACTGCTTGATTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATTCATATCAGTAATCGTTTGATTTCTGATATAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTCCAATGCTAGAGTTACCAGAATTATTAAGTTCGGATT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAGAAGGGAAACCATGGTTTCCATGTATTTAGCGGAATA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GCTTCACACTACGTTTCATTTCTAAATCGTATAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GAGACCTCCGAAGATGCTGTCATTGCCGTTTCCAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CACATCAAATGTGCCGCCTAGCGCAAGTTCCTGCTGCCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATTGGTTAGTCAATGCACACAACTTAATGAATGCAAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTCAGATGAATCTACGACTGTGCTTCCTTGAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAGGAAACAAATAACCCCCCAAAAAAAAAGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACGTATTCTCGGAAATATAGTGACGACCTGCTAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTATGATGAGGAAGATCCACAAAGGATAATCTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACCTGATCCTCCGTGCAGAAGGTCTTCTTGGAAGCCT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CCTTTATCTCATTTGCAAGAAAATTCTGAACATTTGGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTACAAAAGTAACCGCAACTAATGTTCCAACAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAAGACCATCTAGGAAGAAATCTGGAACGTATCC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTTATATATGCAGAAAATGCGGGCTCTCCTACA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTCAACTCTTGCAAGCCTTTCATCAAGCTCTTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTTGATGGTTGAACACTTTTTAGGAACTTCATATTTATA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CGTATTCATCAGATACAATGTTAAAATTATCAAGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTTGAGCTTGCGTGTGATCGTTTCCCATCTTCAGT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTGCGGGTGCAGCTGCAAAAAATGTGCCTAAAATCAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTGTATGTTCATTAGAAACTTTCACGTCTCTGT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AGAATTTGATCATGTCTAACCAAAAGAATGTATTCATC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTACCCAGTAAGGATAAATGCCAACGTTCTTCATC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC

>NC_019678|26|9|6181145-6188351|CRT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTGGGGGAAGTTTGCATATTAACTCGTTACCT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTACCAATGAAGTTTCCAGTGATAGCAATTATGTTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTCATCGTCTCCACCAGTTTCACGTATAACAGAACTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GCTAAGCATGGCACTTAGCCTATAAACTGCTTGATC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTGGTTAGACATTTTAGCAATCCTTTAAAAATAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTGTAGTTCGGTAAAAACCTAAAGGTTCTTCACGGTG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTACGAGCAAGCGGTTTGCTGTTGGGGTAGGCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGCGGGTGTCAACGGTTTCACCACGGACACCATG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTACTTGCTGGTTTAAACAATAAGCTAAGACAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTCCGTCTGCGTTTTTTGACTTTCCGCAAGCCACAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTTTTTAGAAACGCAAAAAATTACTTCCTAAAAGC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTAGGTTATTTTTGTAATAAACCATAGTAGATCTAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGAAGTAAGTCACAAACTAACAACAAATCGTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATTACTTCTCCACAAGCAAGGGCTTGAGAAGGTTGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTGTGATATTCTCTTCTTTCTCTAACCACTTTTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAATGTGCTTTAAATGCAGTTTCAAGCGATTCAAAAGCAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTAATTGCTTTTAATTTCACTTGTTGTTTCCTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTTGAAGAGAAAGAATAGTTTTTTCTTTTTGTTCAGCTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTTTGGGCGAGTAAGTGAAACTTTTTTTCCCGCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATAAGCTAAGACAATAATTGCGCCTTCGTGTCCCCC
CCCCAGCGATTGGGTTAATTCGGATTAGTTGGAAAC	TATAAACTGTGTTTTCGTTAAAACCCCCAACAGCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAAAACAGTGTCAGCATTGACTCTACCAGCTTTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTACATCTTGAATTATTTTCTTTATTCCTAAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGTGTAGTCATGATGACTTACCTCAATTTAAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTCCATGGTGATGATACCATTACAAGCACGGGCAACA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TAACAAGGGATTATGCGATTCAGATCGTAAAAAAAATA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTGGAACTTTGCGTCCACAGATTAGACCTAGTTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATACATTGTTGCCCGTGCTTGTAATGGTATCATC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GGAAACCCAAATTCCTGCTCACCAAGGGGGGCATGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTCAAATGACCGAATACGAACAACTTTTGCAGGTGAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATTCCATTACTGGATTAGCGACAGCAGGGTTCAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATAGATACGGCATTAAGAGCTATAATTCTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATAGAGCAATAAACCCTAAAGCAACACTGACTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTATATATTTTGTAGCGGTTTTAAATTCTGAAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTGGCTACATAACTTTGATTTTCTTCTATGTATTCTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTTAGTAAATTACTTTACAAGAAAAATCTTGTAATTG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTACTTTGTTAGCGAAACCTGTTGCAAACCTAGCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTTCACCAAGCTCTGTTTTCAAAACTTGTTGAACTTTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATGATATGTATCCCAATTGAAGCACGTTTTATTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAAAATATTCACTATGTAAAAAGAAATAAACCTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CACCATTATTTGTTTGAGTGGTAGGGGGATGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GCTAGGGCCCGGCTGGGGAGAGGGCTCCCTATTAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTATTACCTTCATGCTTGGAAAAAATTCTAGACAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACTAACCCACACAATGAGGCTGAATGAATTTTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AGCTGTAGCAATCTTTAAGTAAATCTTAGAAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATCGGAAACATCTTTATTACCTTCATGCTTGGAAAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAGCTTCCAAGAGCGATTTTGAGACTTGCCAGATGCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCGACTGAAAGCGATTGGGCGAAATTTTTTGCTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTGAATGGCATGATGGTAGTTACTTTTGTCAATT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGTAACAGATCCAAGAGCAGCAAAACAGGCACCAGCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAAAAATTAAAATATTACTTAAAATAATTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATTGGCATCGCACTTGCAATTTTCTCCGTATAGCCTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATATATAACTCCCACGTTCAGATGAACGTCTCT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTGGTTAAAAGAGTCGAAATAAACAAATATTACGTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGGCTATAACTATGGTGGTAAGCCACAGGCAATACGCG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTTTTCTCCACAAAATTATAGAAAGAAAAAAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTGATAAGAGAAAGCAAGAAGTTGCAACAATAGCAAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AGTAAGTCCACCAATCTCAAAAACTGTAGTTCCATTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAATATCTCCTAATTTGAGAAATTTCGGTTGCGGTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAATCATTCGACTACTCATTCTAACCCGAACAAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAACTTTACTAGATTGTGGCATAATTTTACCTACCT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AACTAGGAGAAAAACTTGTTTCAGCAACTAAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TAGCTATTGCGGATTGCAGCAGATAACTTGATAACT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTAAAGAAGTTGTGTAGCTTGCCCGTATATCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATTATACTAGCTTCTGAACTACCAGACATTTCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AACTTGATTAACGTCAAATTTGTTAAGAGTTTCTTCAATCC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACCTGCACACTTGCCTTTAGTTCTAACATCAGAAGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACTATTAGAACCATTGTGTTTTACAAACACAGTGTCTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAGGAGTTAATCTGATTAGTCTACCAACGTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTTAGTGGTTTTTTGCGAACCTGCAAATCCG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATGCTGCAACTAACGTTAAAACCACAAATACCAAAAAATA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTTCTTCCTCCATCTCGCACTTAGAAGGGTGTG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATCTAAATAAGAATAATACAACTACCACATCTCGCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATTGATCTTCATAGTCAAAATTTTCTTCTTTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAATGTATTCTGCAGCAGAAAGAAAAAACACTCTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTCACTTCTTGCAATCTTTCAACTGCTTGATTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATTCATATCAGTAATCGTTTGATTTCTGATATAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTCCAATGCTAGAGTTACCAGAATTATTAAGTTCGGATT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAGAAGGGAAACCATGGTTTCCATGTATTTAGCGGAATA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GCTTCACACTACGTTTCATTTCTAAATCGTATAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GAGACCTCCGAAGATGCTGTCATTGCCGTTTCCAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CACATCAAATGTGCCGCCTAGCGCAAGTTCCTGCTGCCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATTGGTTAGTCAATGCACACAACTTAATGAATGCAAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTCAGATGAATCTACGACTGTGCTTCCTTGAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAGGAAACAAATAACCCCCCAAAAAAAAAGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACGTATTCTCGGAAATATAGTGACGACCTGCTAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTATGATGAGGAAGATCCACAAAGGATAATCTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACCTGATCCTCCGTGCAGAAGGTCTTCTTGGAAGCCT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CCTTTATCTCATTTGCAAGAAAATTCTGAACATTTGGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTACAAAAGTAACCGCAACTAATGTTCCAACAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAAGACCATCTAGGAAGAAATCTGGAACGTATCC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTTATATATGCAGAAAATGCGGGCTCTCCTACA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTCAACTCTTGCAAGCCTTTCATCAAGCTCTTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTTGATGGTTGAACACTTTTTAGGAACTTCATATTTATA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CGTATTCATCAGATACAATGTTAAAATTATCAAGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTTGAGCTTGCGTGTGATCGTTTCCCATCTTCAGT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTGCGGGTGCAGCTGCAAAAAATGTGCCTAAAATCAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTGTATGTTCATTAGAAACTTTCACGTCTCTGT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AGAATTTGATCATGTCTAACCAAAAGAATGTATTCATC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTACCCAGTAAGGATAAATGCCAACGTTCTTCATC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC

>NC_019678|26|10|6185152-6188351|PILER-CR
	TTGGGGGAAGTTTGCATATTAACTCGTTACCT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTACCAATGAAGTTTCCAGTGATAGCAATTATGTTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTCATCGTCTCCACCAGTTTCACGTATAACAGAACTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GCTAAGCATGGCACTTAGCCTATAAACTGCTTGATC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTGGTTAGACATTTTAGCAATCCTTTAAAAATAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTGTAGTTCGGTAAAAACCTAAAGGTTCTTCACGGTG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTACGAGCAAGCGGTTTGCTGTTGGGGTAGGCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGCGGGTGTCAACGGTTTCACCACGGACACCATG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTACTTGCTGGTTTAAACAATAAGCTAAGACAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTCCGTCTGCGTTTTTTGACTTTCCGCAAGCCACAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTTTTTAGAAACGCAAAAAATTACTTCCTAAAAGC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTAGGTTATTTTTGTAATAAACCATAGTAGATCTAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGAAGTAAGTCACAAACTAACAACAAATCGTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATTACTTCTCCACAAGCAAGGGCTTGAGAAGGTTGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTGTGATATTCTCTTCTTTCTCTAACCACTTTTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAATGTGCTTTAAATGCAGTTTCAAGCGATTCAAAAGCAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTAATTGCTTTTAATTTCACTTGTTGTTTCCTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTTGAAGAGAAAGAATAGTTTTTTCTTTTTGTTCAGCTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTTTGGGCGAGTAAGTGAAACTTTTTTTCCCGCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATAAGCTAAGACAATAATTGCGCCTTCGTGTCCCCC
CCCCAGCGATTGGGTTAATTCGGATTAGTTGGAAAC	TATAAACTGTGTTTTCGTTAAAACCCCCAACAGCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAAAACAGTGTCAGCATTGACTCTACCAGCTTTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTACATCTTGAATTATTTTCTTTATTCCTAAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGTGTAGTCATGATGACTTACCTCAATTTAAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTCCATGGTGATGATACCATTACAAGCACGGGCAACA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TAACAAGGGATTATGCGATTCAGATCGTAAAAAAAATA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTGGAACTTTGCGTCCACAGATTAGACCTAGTTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATACATTGTTGCCCGTGCTTGTAATGGTATCATC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GGAAACCCAAATTCCTGCTCACCAAGGGGGGCATGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTCAAATGACCGAATACGAACAACTTTTGCAGGTGAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATTCCATTACTGGATTAGCGACAGCAGGGTTCAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATAGATACGGCATTAAGAGCTATAATTCTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATAGAGCAATAAACCCTAAAGCAACACTGACTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTATATATTTTGTAGCGGTTTTAAATTCTGAAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTGGCTACATAACTTTGATTTTCTTCTATGTATTCTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTTAGTAAATTACTTTACAAGAAAAATCTTGTAATTG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTACTTTGTTAGCGAAACCTGTTGCAAACCTAGCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTTCACCAAGCTCTGTTTTCAAAACTTGTTGAACTTTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATGATATGTATCCCAATTGAAGCACGTTTTATTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAAAATATTCACTATGTAAAAAGAAATAAACCTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CACCATTATTTGTTTGAGTGGTAGGGGGATGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GCTAGGGCCCGGCTGGGGAGAGGGCTCCCTATTAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTATTACCTTCATGCTTGGAAAAAATTCTAGACAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACTAACCCACACAATGAGGCTGAATGAATTTTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AGCTGTAGCAATCTTTAAGTAAATCTTAGAAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATCGGAAACATCTTTATTACCTTCATGCTTGGAAAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAGCTTCCAAGAGCGATTTTGAGACTTGCCAGATGCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCGACTGAAAGCGATTGGGCGAAATTTTTTGCTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTGAATGGCATGATGGTAGTTACTTTTGTCAATT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TGTAACAGATCCAAGAGCAGCAAAACAGGCACCAGCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAAAAATTAAAATATTACTTAAAATAATTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATTGGCATCGCACTTGCAATTTTCTCCGTATAGCCTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATATATAACTCCCACGTTCAGATGAACGTCTCT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTGGTTAAAAGAGTCGAAATAAACAAATATTACGTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTGGCTATAACTATGGTGGTAAGCCACAGGCAATACGCGCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACATTTTTCTCCACAAAATTATAGAAAGAAAAAATCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTGATAAGAGAAAGCAAGAAGTTGCAACAATAGCAAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AGTAAGTCCACCAATCTCAAAAACTGTAGTTCCATTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAATATCTCCTAATTTGAGAAATTTCGGTTGCGGTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAATCATTCGACTACTCATTCTAACCCGAACAAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAACTTTACTAGATTGTGGCATAATTTTACCTACCT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AACTAGGAGAAAAACTTGTTTCAGCAACTAAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TAGCTATTGCGGATTGCAGCAGATAACTTGATAACT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTAAAGAAGTTGTGTAGCTTGCCCGTATATCAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATTATACTAGCTTCTGAACTACCAGACATTTCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AACTTGATTAACGTCAAATTTGTTAAGAGTTTCTTCAATCC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACCTGCACACTTGCCTTTAGTTCTAACATCAGAAGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACTATTAGAACCATTGTGTTTTACAAACACAGTGTCTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAGGAGTTAATCTGATTAGTCTACCAACGTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTTAGTGGTTTTTTGCGAACCTGCAAATCCG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATGCTGCAACTAACGTTAAAACCACAAATACCAAAAAATA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GTTCTTCCTCCATCTCGCACTTAGAAGGGTGTG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CATCTAAATAAGAATAATACAACTACCACATCTCGCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATTGATCTTCATAGTCAAAATTTTCTTCTTTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAATGTATTCTGCAGCAGAAAGAAAAAACACTCTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTCACTTCTTGCAATCTTTCAACTGCTTGATTAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AATTCATATCAGTAATCGTTTGATTTCTGATATAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTCCAATGCTAGAGTTACCAGAATTATTAAGTTCGGATT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AAGAAGGGAAACCATGGTTTCCATGTATTTAGCGGAATA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GCTTCACACTACGTTTCATTTCTAAATCGTATAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GAGACCTCCGAAGATGCTGTCATTGCCGTTTCCAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CACATCAAATGTGCCGCCTAGCGCAAGTTCCTGCTGCCA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GATTGGTTAGTCAATGCACACAACTTAATGAATGCAAT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTCAGATGAATCTACGACTGTGCTTCCTTGAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAGGAAACAAATAACCCCCCAAAAAAAAAGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACGTATTCTCGGAAATATAGTGACGACCTGCTAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTATGATGAGGAAGATCCACAAAGGATAATCTC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ACCTGATCCTCCGTGCAGAAGGTCTTCTTGGAAGCCT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CCTTTATCTCATTTGCAAGAAAATTCTGAACATTTGGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTACAAAAGTAACCGCAACTAATGTTCCAACAAA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTAAGACCATCTAGGAAGAAATCTGGAACGTATCC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTTATATATGCAGAAAATGCGGGCTCTCCTACA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTCAACTCTTGCAAGCCTTTCATCAAGCTCTTTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTTTGATGGTTGAACACTTTTTAGGAACTTCATATTTATA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CGTATTCATCAGATACAATGTTAAAATTATCAAGA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTTGAGCTTGCGTGTGATCGTTTCCCATCTTCAGT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TCTGCGGGTGCAGCTGCAAAAAATGTGCCTAAAATCAG
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	ATTGTATGTTCATTAGAAACTTTCACGTCTCTGT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	AGAATTTGATCATGTCTAACCAAAAGAATGTATTCATC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CTACCCAGTAAGGATAAATGCCAACGTTCTTCATC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015120904.1|6180649_6180925_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|378256
NC_019678.1|WP_015120907.1|6192760_6194158_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|377670
NC_019678.1|WP_015120902.1|6178419_6179382_+|Retron-type-reverse-transcriptase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209
NC_019678.1|WP_015120911.1|6196874_6197222_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120898.1|6174283_6174718_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120893.1|6168046_6168403_-|four-helix-bundle-protein	unknown	unknown	gnl|CDD|274132
NC_019678.1|WP_015120910.1|6196256_6196832_+|NYN-domain-containing-protein	unknown	unknown	gnl|CDD|350235
NC_019678.1|WP_015120899.1|6174985_6175342_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120897.1|6173938_6174184_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120908.1|6194750_6195404_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_044291151.1|6166654_6166969_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120901.1|6177291_6177882_+|HD-domain-containing-protein	unknown	unknown	gnl|CDD|379122
NC_019678.1|WP_044292273.1|6179546_6180551_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NC_019678.1|WP_015120912.1|6197382_6197601_+|hypothetical-protein	unknown	unknown	gnl|CDD|316933
NC_019678.1|WP_015120906.1|6191637_6192771_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379165
NC_019678.1|WP_157229455.1|6198339_6199731_+|ThiF-family-adenylyltransferase	unknown	unknown	gnl|CDD|366360
NC_019678.1|WP_015120900.1|6175492_6177022_+|TIGR03985-family-CRISPR-associated-protein	WYL	mkCas0075_WYL_CAS-I:CAS-III	gnl|CDD|274901
NC_019678.1|WP_015120905.1|6188914_6191641_+|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|378037
NC_019678.1|WP_015120913.1|6197626_6198112_+|hypothetical-protein	unknown	unknown	gnl|CDD|373079
NC_019678.1|WP_015120909.1|6195458_6195911_-|DUF4112-domain-containing-protein	unknown	unknown	gnl|CDD|379180

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019678.1|WP_015120904.1|6180649_6180925_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	8.2e-26	85.0	0.3
NC_019678.1|WP_015120902.1|6178419_6179382_+|Retron-type-reverse-transcriptase	RT	pfam00078_RT_CAS-I:CAS-III	2.5e-51	169.0	0.6
NC_019678.1|WP_015120900.1|6175492_6177022_+|TIGR03985-family-CRISPR-associated-protein	WYL	mkCas0075_WYL_CAS-I:CAS-III	1.7e-162	536.3	15.7
NC_019678.1|WP_044292273.1|6179546_6180551_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	8.6e-90	295.7	0.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015120904.1|6180649_6180925_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	2.53405e-26
NC_019678.1|WP_015120907.1|6192760_6194158_+|helix-turn-helix-domain-containing-protein	gnl|CDD|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	1.68595e-18
NC_019678.1|WP_015120902.1|6178419_6179382_+|Retron-type-reverse-transcriptase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	1.93211e-92
NC_019678.1|WP_015120910.1|6196256_6196832_+|NYN-domain-containing-protein	gnl|CDD|350235	cd10911, PIN_LabA, PIN domain of Synechococcus elongatus LabA (low-amplitude and bright) and related proteins. This subfamily contains Synechococcus elongatus PCC 7942 LabA which participates in cyanobacterial circadian timing, it is required for negative feedback regulation of the autokinase/autophosphatase KaiC, a central component of the circadian clock system, and appears to be necessary for KaiC-dependent repression of gene expression. This subfamily belongs to the LabA-like domain family which includes the N-terminal domain of limkain b1, a human autoantigen localized to a subset of ABCD3 and PXF marked peroxisomes. Also included in the LabA-like domain family are human ZNF451, uncharacterized Bacillus subtilis YqxD, uncharacterized Escherichia coli YaiI, and the N-terminal domain of a well-conserved group of mainly bacterial proteins with no defined function, which contain a C-terminal LabA_like_C domain. Curiously Pseudomonas putida S16 NicB , which is described as a putative NADH-dependent hydroxylase involved in the microbial degradation of nicotine also falls into the LabA-like family. The PIN (PilT N terminus) domain belongs to a large nuclease superfamily. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.25445e-43
NC_019678.1|WP_015120893.1|6168046_6168403_-|four-helix-bundle-protein	gnl|CDD|274132	TIGR02436, S23_ribosomal_protein, four helix bundle protein. This family describes a protein of unknown function whose structure is a bundle of four long alpha helices. Some of the first members of this family were found encoded in the (atypically large) intervening sequence (IVS) of Leptospira 23S RNA, a region often present in the rRNA gene and removed during rRNA processing without re-ligation. However, this location is not conserved, and naming this protein as a 23S RNA protein is both confusing and inaccurate.	2.89969e-34
NC_019678.1|WP_015120912.1|6197382_6197601_+|hypothetical-protein	gnl|CDD|316933	pfam14453, ThiS-like, ThiS-like ubiquitin. A member of the ubiquitin superfamily that is often fused to the ThiF-like (E1)- ubiquitin activating enzyme and is present in gene neighborhoods with components of the thiamine biosynthesis pathway.	9.27918e-05
NC_019678.1|WP_157229455.1|6198339_6199731_+|ThiF-family-adenylyltransferase	gnl|CDD|366360	pfam00899, ThiF, ThiF family. This domain is found in ubiquitin activating E1 family and members of the bacterial ThiF/MoeB/HesA family. It is repeated in Ubiquitin-activating enzyme E1.	3.68064e-23
NC_019678.1|WP_015120901.1|6177291_6177882_+|HD-domain-containing-protein	gnl|CDD|379122	pfam13328, HD_4, HD domain. HD domains are metal dependent phosphohydrolases.	1.17425e-35
NC_019678.1|WP_044292273.1|6179546_6180551_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	3.09441e-105
NC_019678.1|WP_015120906.1|6191637_6192771_+|AAA-family-ATPase	gnl|CDD|379165	pfam13401, AAA_22, AAA domain.	1.79869e-05
NC_019678.1|WP_015120900.1|6175492_6177022_+|TIGR03985-family-CRISPR-associated-protein	gnl|CDD|274901	TIGR03985, hypothetical_protein_sll7078, CRISPR-associated protein, TIGR03985 family. Members of this protein family belong to CRISPR-associated (Cas) gene clusters. The majority of members are Cyanobacterial.	5.65075e-76
NC_019678.1|WP_015120905.1|6188914_6191641_+|DDE-type-integrase/transposase/recombinase	gnl|CDD|378037	pfam08722, Tn7_Tnp_TnsA_N, TnsA endonuclease N terminal. The Tn7 transposase is composed of proteins TnsA and TnsB. DNA breakage at the 5' end of the transposon is carried out by TnsA, and breakage and joining at the 3' end is carried out by TnsB. The N terminal domain of TnsA is catalytic.	4.05937e-08
NC_019678.1|WP_015120913.1|6197626_6198112_+|hypothetical-protein	gnl|CDD|373079	pfam14462, Prok-E2_E, Prokaryotic E2 family E. A member of the E2/UBC superfamily of proteins found in diverse bacteria. Analysis of the active site residues suggest that members of this family are inactive as they lack the characteristic catalytic residues of the E2 enzymes. They are usually fused to or in the neighborhood of a multi/poly ubiquitin domain protein. Other proteins of the ubiquitin modification pathway such as the E1 and JAB proteins are also found in its gene neighborhood along with a distinct predicted metal-binding protein.	0.000135461
NC_019678.1|WP_015120909.1|6195458_6195911_-|DUF4112-domain-containing-protein	gnl|CDD|379180	pfam13430, DUF4112, Domain of unknown function (DUF4112). This family has several highly conserved GD sequence-motifs of unknown function. The family is found in bacteria, archaea and fungi.	1.05827e-10

Protein sequences

>NC_019678.1|WP_015120904.1|6180649_6180925_+|CRISPR-associated-endonuclease-Cas2
MLVVVVYDIPNDKRRTKLSNFLEGYGQRVQFSVFECFLNLDEMRQLFEKSKKIVKPSEDNVRFYWISEDAVSRVLTIGSEHPNAPPNYYVI
>NC_019678.1|WP_044292273.1|6179546_6180551_+|CRISPR-associated-endonuclease-Cas1
MAAIYLIEQGTNIYKDYQRFIIHVSEKPKLEVPIRDVQQIIVFGNIQLSTPVIQACLKEQIPVVFLSQTGTYHGHLWSEKSIHLDNQLVQAERRNDDLFRFSVSRAVVLGKLLNSKQLLMRFNRRRKIGKVEEAIYGINQDIDALNYVDNLDTLRGYEGIAAARYFPAFGNLITNPKFSFSQRFRQPPTDEINSLLSFGYTLLFNNVLSFIITEGLSPYIGHFHYGDKQKTYLAFDLMEEFRSPIVDSLVLKIINKSLFKPQDFDVVASTGGVYLSQTSRRVFLKQFENRMNEEISHPDLISQVTYRHAIQLQVRRYKRCLLSDNIYESFLRAD
>NC_019678.1|WP_015120902.1|6178419_6179382_+|Retron-type-reverse-transcriptase
MISSQFIDINNFQRAWEKVADKRGCAGVDGETISSFASNQTVNVYQLMNSVADGSYQPFPCKQVIIPKRNGSQRELKIPTIRDRIVQQALLNVISPLMEEKFSPVSFAYRPNLSYINAVEKIADWRDMGYVWVLDADIVKFFDNIDHHRLLQQVRLHIDHPGILCLIKAWISVGVETREGLILPQKGIPQGAVISPILANIYLHEFDEIISASDLEIVRYADDFLVLSTSQERIAIAKSQVIDLLDSLGLEINTDKTQITSFERGFRFLGHGFLSDAIFPVDTNKAKLKSGIETNREKTRTRKTSKKKLYHNPYRNKKVV
>NC_019678.1|WP_015120901.1|6177291_6177882_+|HD-domain-containing-protein
MNLNTTQKYFLTNRFEQALVYASRLHRKQIRKGSNIPYISHLLSVTALVLEDGGDEDEAIAALLHDAVEDQGGQATREVIFDMFGLKVAEIVDGCSDTNTIPKPPWLQRKQQYIDNLRGASASIRKVSLADKLHNARSILRDLSSNGESTWGKFKGGKEGTLWYYQTLLQLFLETNADSWMVQEFKRIVEQFSVNS
>NC_019678.1|WP_015120900.1|6175492_6177022_+|TIGR03985-family-CRISPR-associated-protein
MKREVFNYPPSVEVLKILTAGSLKQNLAKAVRIWVILRSIYGDESDEVKLELKEEFSFLEWRDLFFIDAKKYHQRDCIPNLHYVNQLNQNFIKEECRCAIKLKQWLFESSLRIDENHWCQSLKKYYSFEGDELNNLLQGGIAKNKSQHIQSEVKSLTVNKKFSKSLPEGRLFAVTGRNLKDNDFQSLVNLGWLNIKKYSGKVIYTKVNRFPEVFLSSLKNKEITSEQFTNHELSAFNNSLSQPINGIQRFFIHAEYIVHSSLNEHIELLQQKIKSLWKRDKVPLVKLNYRSAKLYQETIDCIVYPVCIYYYKRAPYLFAYGQIPQSNRKNPWSKIDWYDYRLDKIINLDELNKLDSNADNLDIPKHFLDKCYGKYPPNPDEIKDKMSAVWGFDIHKPQALLILRFDQYFYGNYIEGTERDDMFHKITRKQVEKLIKSYTPKASLEQKQLISTVQSRSEYDIYCKIDYRVDDNNIVMRLRAWCPNVEVIFPLDLRDRMRREMQEAYFMHR
>NC_019678.1|WP_015120899.1|6174985_6175342_-|hypothetical-protein
MSRFQERFNAKMKEWYDSDKSITKLFTTEYERMLAYLWACSEARKSEENIAEIKEFGRTNIKALGDSNYSQLLRTRDYCCRCGETYRLENLSICVECDNLFCYRCSRKKCGCGGEVVG
>NC_019678.1|WP_015120898.1|6174283_6174718_-|hypothetical-protein
MPFKFNHKYLVLITLLLFTNSCSAPKKSQAKLDAEFEQLLNQQIESRRGSTPKIREVFDKYIGKSEAKKIGNGICKSIKNSTFQKDIKAHWDKMSDLKREKKLSNRVMNDINASHVYIRTAAVNSYCPEYKVQIYKELAKTGEE
>NC_019678.1|WP_015120897.1|6173938_6174184_-|hypothetical-protein
MIQAIDSEQIFVSNLEQFISKADKFIKTYYSGVSDENHVQEIVQELKNLVLDTDLKQLEFDYQHYCEIEDLMGDCDESAWF
>NC_019678.1|WP_015120893.1|6168046_6168403_-|four-helix-bundle-protein
MINNISITDRTKKFAVRIIKACCFLDEKPGVNRIISSQLLRSGTSIGANVREAQSAQSDKDFISKLEIALKEARETQYWLEIIIESELVEKSKFDSLLQEANEIGKILVSSTKKLKQK
>NC_019678.1|WP_044291151.1|6166654_6166969_-|hypothetical-protein
MESNIEIYRSTTIKLLDSTYLNTFILSGFVELVICYADNEKFTIEFHPNQIPILEKLLNNLRSVTEQQINQKIETLQWELEEIKSCDCQIQVSEFLQNGNGVKQ
>NC_019678.1|WP_015120905.1|6188914_6191641_+|DDE-type-integrase/transposase/recombinase
MLSTQEFEEWCRRLKLPEVTRKVISQIRSTEPVRQVKSLGGNVSGNYCSQKMGKTLQFESHKVELPGIEEYETCSDVLEFYDQPYQLTLKFMTKKGREVTVTHIPDFFVIRQQSAGFEEWKPQAKLEKLSLLQPNRYVKNQDGQWTSPPAEEQAQLYGCYYRIRSDAEIDWIKYRNRQFLRSYAEQKYQIGTEIATFIKSLVSSQPGITYLKLLQYQNVNPDHINALLATEELYIDLSAAPLAEPEKVHIFRNQEMALAHNLTSVSQNLTVANSLQIIDVAVGTSFCWDGQPLTVLHNGESKIVLRSSNSLIHLTHSEFDLLVQRGEIVGLKVPEQIGIHPEAIERFLKASPQALAEANKRYLVIEPYLHGQKRENETVSLRTIRNWKAKFKAAEQKYCWGYIGLIDNHAAKGNRLPKISTEVWEFVDKIIESHYETLKQRGKLAVYGVLSQEWEKAGRIEHLPSYVTFSSRIKQRSGYQQTKKRLGSRAAYQKSNFYWELEFTTPRHGDRPFEICHIDHTQLDIELVCSRTGRTLGRPWATLLIDATSRRILAIYLTFDEPSYRSCMMVLRICVQRFSRFPETIVVDGGAEFGSTYFETLLAAFGCTKKQRPAAKARFGSVIERIFGTTNTEFFYNLRGNTQITKNVRVVTKSNNPKGQAVWTLDELYEHFCAYSYELYDCKEHPALLQSPRQAFLSGLALSGSRPHKKILYDQNFRIFTLPSTPKGTAKVQPSRGVKINYLYYWSVDDSFINPEVEGTNVPVRYDPFDMGTAYTYVKGQWVRCISDYYKSFHNCSEREVKLASLELHRSRQKVSQVITISAKEKAAYLESAEAKEVLLLQRLHDLARLDVHSIIEGERSGHNHPQNIALNQKNPELDTNFNSTKDESVILEHLNTIEPYKNEELWK
>NC_019678.1|WP_015120906.1|6191637_6192771_+|AAA-family-ATPase
MNKERPFPEELLLQSSQIKTSYFKSITVPHKKLKRALDTLLLNILEPADTLVFLVFGVTGVGKTTLRLRLEKLLSEEFIADIQSNPGQIAVAGLEAIPAERGNFSYKDYYTRALEALKEVLVEYKVNYGLTEPDSQELKHDYHINGKDSPALRRAMEKVFRYRQIKAFTVDEAQHLLMISGGHQMLQQMNWIKSIANLTGTIHILFGTYELLNCPTLNGQVGRRSEDIHLSPYYADQPEDVAEFIRVTNTFQRHLPLQKEPDLEKHYEYLLEGSVGCVGILKNWLTRSLRVALAESATTLTTSHLKQGAFGASRINKIRSEAQQGERRLLESEGLSFHLESSNVSNNQAVNKSSTKKGRVGQRNPKRDAVGMKQYDS
>NC_019678.1|WP_015120907.1|6192760_6194158_+|helix-turn-helix-domain-containing-protein
MTVNLDTKNELWDLEPPSFLPRSRLFHLLPIGVGTPYVESLTSYVSRLAVAHSVSTGTLLAIEVGPLIKTNYSANRKSIVAIYGQESVRALNGIRLGALQLVRALETLTLRTDLQFLTMLPWTEVFPALGLLKHEQAWCPLCLEEWLENRKVIYLPLLWALNVVKVCPYHHQPLQSQCPHCHAQFLPLWRSSRPGYCLKCSGWLGSSKDARDVEPNFFEATDEFQWNIWAANTLGNLIAQAPSQHSPLPRETIKKALVFFVNKFSNGDVSAFGQLIGVPSSKITQWYSGKTIPTLDKLLKICYRLQISLIKFLQPELKQQVNTNQVTLCPSPQQRQLTVTSQRNKARIRSLLKSVLNQNEYPSPSVREVARRYHIGGATLYRYAPDLCQAISARYWDYKKLLQQQTIQQGINEVKRLTPELYAQGITPSVKNLASVMTNPEALWREEVLETLSEVRRSLGELPER
>NC_019678.1|WP_015120908.1|6194750_6195404_-|hypothetical-protein
MNKLIAGIAALALWTVSTGVANSQQVTRFKHQDDSYYHQRLNSKGIARYQYKIPANSFGVFTLKNHSRRSDFDIYVYDSSNGKLLTEGKSYGTKTELVITQPVGRDRYAYIKVLNYGSRTSRYKLYANYVNPGTKFLIAFAGIPFCSSARNINDRTSSRVITGISSMLQGSDFGGVARDVFINELTMEMRKQFGYGCMGEIAVNWVVSMAKGFYRNY
>NC_019678.1|WP_015120909.1|6195458_6195911_-|DUF4112-domain-containing-protein
MDINKSLPVKIQAHEANLIQTKHEIQKFIKMSEGLLFDQVGLDALIGAIPGVGGMYTGIMGIWLLLQSYKVRAENEDKLMIVALTFVDVVVGIVPIFGDIIDTFLRVHALNGSRLITHIDKQLSLIENTREQLNQGFNPDLSSLENLLLR
>NC_019678.1|WP_015120910.1|6196256_6196832_+|NYN-domain-containing-protein
MGNLHRVMIIADGDNAFMAAQSFNRKINWHKMRDYLADPKEGRELIEMVIYFGLPPAKDRFEEQRKSKEKFIYWAKSNGFLIVTKEGKAKGDGYENNVDVVMAIDAMELALEIKPDIVVLVTGDSDFAYLAQKLRRRGIRVEVASVEQSLGSELKNSANSVVDLTEVFDEFDPHNSNENFHRIGHANVFDA
>NC_019678.1|WP_015120911.1|6196874_6197222_+|hypothetical-protein
METVNGKLTNQKLNQFDEITHNIEYINRRCEYLQSQLTHISSQDNLQYLQKLEQRIGFLEELTSKQSKQISFIKIGSIIALLFVWSISGMNNQQKDDNTQLPKQVYSYIAPFSTD
>NC_019678.1|WP_015120912.1|6197382_6197601_+|hypothetical-protein
MRAIVNGKLVDLPKGATVEELRKKLPEIGQDDVMEEGFGGTRPLKSNEALKEGSKVWTVPKIVKGSDKSSKK
>NC_019678.1|WP_015120913.1|6197626_6198112_+|hypothetical-protein
MAITISKDKSGFKPSSRIIEELKLLEKVAKNIIVGSKTVGDTRYTAVLIKGMPLSSQKFKVSNTDVLFLLPSDYPRLPPIGCYLNYPWNTVGEGDHHFTRQSYYGAPFLSEQGWYWYCVGLGGGFNHDVWLNSWRPSNNAENGHNLTTLFVTARHAINSDD
>NC_019678.1|WP_157229455.1|6198339_6199731_+|ThiF-family-adenylyltransferase
MWSDFQKSMLSSRMFNEEVIGFLFCQRHQVSKRKVRYIPKTWVVPTSECYEHQSTDGLVLTQRFHSYLLENHLFPGLDIVHIHTHAGVGIPEFSYVDNRYESEYAKFIASHFPEKPRLVSGVFDEGLDNCKFRIWDRKGREFQQVDFCNSLFEISDSENIFDNPNLMFARQKTFGETNQKTLNQLKVGLIGCGGIGSIFAELLGRLGVKNWVLVDPDKLEQVNLNRMTGATQEMVEHGWYKVHYVKHLIKKIYACGSHVKTISTAIEAETATQEIANCDLIVVATDNHLSRKTAQEVALKYMRPLVCLGTHIDVKPDGTPRMYCRITVPPLGGDWCLMCGNIINLQRAALESAPSEINHMAENAGYLEGVNDPSVFWLNSICASTAVGVIHGIVSGFMNVDSGIDWIYEFPGSEWRKTDTTYLQTDDCYFCGLNSSENLVQESDYESPDFEEQDFDNSDFIVW

Crispr_ID: NC_019678_27

• CRISPR_ID: NC_019678_27
• CRISPR_location: 6194395-6194646
• CRISPR_type: TypeIII
• Repeat_type: A:N
• Spacer_info: 3 spacers
• Cas_protein_info: cas2,cas1,RT,WYL,csx3

Consensus repeat of NC_019678_27

Consensus_repeat	Method
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	PILER-CR
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CRISPRCasFinder
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	CRT

spacers of NC_019678_27

>27.1|6194431|37|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTTGGTATGTTGAATTTAAAAATTCAACAACTCACTA
>27.2|6194504|38|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTCCGTATTTCCAGGGAATATGGTGGCATATATGTAAC
>27.3|6194578|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GCTGTGTAGTATTGTTTAACATATAATGAACTT

CRISPR arrays and Neighbor proteins around NC_019678_27

CRISPR arrays

The CRISPR arrays of NC_019678_27

>merge|NC_019678|27|6194395-6194646|PILER-CR,CRISPRCasFinder,CRT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTTGGTATGTTGAATTTAAAAATTCAACAACTCACTACCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACTTCCGTATTTCCAGGGAATATGGTGGCATATATGTAACCCCCACCGATTGGGTTAATTCGGATTAGTTGGAAACGCTGTGTAGTATTGTTTAACATATAATGAACTTCCCCACCGATTGGGTTAATTCGGATTAGTTGGAACA

>NC_019678|27|11|6194395-6194646|PILER-CR
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTGGTATGTTGAATTTAAAAATTCAACAACTCACTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTCCGTATTTCCAGGGAATATGGTGGCATATATGTAAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GCTGTGTAGTATTGTTTAACATATAATGAACTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAACA

>NC_019678|27|24|6194395-6194646|CRISPRCasFinder
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTGGTATGTTGAATTTAAAAATTCAACAACTCACTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTCCGTATTTCCAGGGAATATGGTGGCATATATGTAAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GCTGTGTAGTATTGTTTAACATATAATGAACTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAACA

>NC_019678|27|10|6194395-6194646|CRT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTTGGTATGTTGAATTTAAAAATTCAACAACTCACTA
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	TTCCGTATTTCCAGGGAATATGGTGGCATATATGTAAC
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAAAC	GCTGTGTAGTATTGTTTAACATATAATGAACTT
CCCCACCGATTGGGTTAATTCGGATTAGTTGGAACA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015120904.1|6180649_6180925_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|378256
NC_019678.1|WP_015120907.1|6192760_6194158_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|377670
NC_019678.1|WP_015120918.1|6202967_6203957_+|hypothetical-protein	csx3	mkCas0115_csx3_CAS-I:CAS-III	unknown
NC_019678.1|WP_015120902.1|6178419_6179382_+|Retron-type-reverse-transcriptase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209
NC_019678.1|WP_015120911.1|6196874_6197222_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120898.1|6174283_6174718_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120910.1|6196256_6196832_+|NYN-domain-containing-protein	unknown	unknown	gnl|CDD|350235
NC_019678.1|WP_015120899.1|6174985_6175342_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_157229455.1|6198339_6199731_+|ThiF-family-adenylyltransferase	unknown	unknown	gnl|CDD|366360
NC_019678.1|WP_015120908.1|6194750_6195404_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120901.1|6177291_6177882_+|HD-domain-containing-protein	unknown	unknown	gnl|CDD|379122
NC_019678.1|WP_044292273.1|6179546_6180551_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NC_019678.1|WP_157229320.1|6202159_6202327_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120912.1|6197382_6197601_+|hypothetical-protein	unknown	unknown	gnl|CDD|316933
NC_019678.1|WP_015120906.1|6191637_6192771_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379165
NC_019678.1|WP_015120900.1|6175492_6177022_+|TIGR03985-family-CRISPR-associated-protein	WYL	mkCas0075_WYL_CAS-I:CAS-III	gnl|CDD|274901
NC_019678.1|WP_015120905.1|6188914_6191641_+|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|378037
NC_019678.1|WP_015120913.1|6197626_6198112_+|hypothetical-protein	unknown	unknown	gnl|CDD|373079
NC_019678.1|WP_015120909.1|6195458_6195911_-|DUF4112-domain-containing-protein	unknown	unknown	gnl|CDD|379180
NC_019678.1|WP_015120916.1|6200523_6202047_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019678.1|WP_015120904.1|6180649_6180925_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	8.2e-26	85.0	0.3
NC_019678.1|WP_015120902.1|6178419_6179382_+|Retron-type-reverse-transcriptase	RT	pfam00078_RT_CAS-I:CAS-III	2.5e-51	169.0	0.6
NC_019678.1|WP_015120918.1|6202967_6203957_+|hypothetical-protein	csx3	mkCas0115_csx3_CAS-I:CAS-III	3.5e-116	381.9	0.2
NC_019678.1|WP_015120900.1|6175492_6177022_+|TIGR03985-family-CRISPR-associated-protein	WYL	mkCas0075_WYL_CAS-I:CAS-III	1.7e-162	536.3	15.7
NC_019678.1|WP_044292273.1|6179546_6180551_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	8.6e-90	295.7	0.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015120904.1|6180649_6180925_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	2.53405e-26
NC_019678.1|WP_015120907.1|6192760_6194158_+|helix-turn-helix-domain-containing-protein	gnl|CDD|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	1.68595e-18
NC_019678.1|WP_015120902.1|6178419_6179382_+|Retron-type-reverse-transcriptase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	1.93211e-92
NC_019678.1|WP_015120910.1|6196256_6196832_+|NYN-domain-containing-protein	gnl|CDD|350235	cd10911, PIN_LabA, PIN domain of Synechococcus elongatus LabA (low-amplitude and bright) and related proteins. This subfamily contains Synechococcus elongatus PCC 7942 LabA which participates in cyanobacterial circadian timing, it is required for negative feedback regulation of the autokinase/autophosphatase KaiC, a central component of the circadian clock system, and appears to be necessary for KaiC-dependent repression of gene expression. This subfamily belongs to the LabA-like domain family which includes the N-terminal domain of limkain b1, a human autoantigen localized to a subset of ABCD3 and PXF marked peroxisomes. Also included in the LabA-like domain family are human ZNF451, uncharacterized Bacillus subtilis YqxD, uncharacterized Escherichia coli YaiI, and the N-terminal domain of a well-conserved group of mainly bacterial proteins with no defined function, which contain a C-terminal LabA_like_C domain. Curiously Pseudomonas putida S16 NicB , which is described as a putative NADH-dependent hydroxylase involved in the microbial degradation of nicotine also falls into the LabA-like family. The PIN (PilT N terminus) domain belongs to a large nuclease superfamily. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.25445e-43
NC_019678.1|WP_015120912.1|6197382_6197601_+|hypothetical-protein	gnl|CDD|316933	pfam14453, ThiS-like, ThiS-like ubiquitin. A member of the ubiquitin superfamily that is often fused to the ThiF-like (E1)- ubiquitin activating enzyme and is present in gene neighborhoods with components of the thiamine biosynthesis pathway.	9.27918e-05
NC_019678.1|WP_157229455.1|6198339_6199731_+|ThiF-family-adenylyltransferase	gnl|CDD|366360	pfam00899, ThiF, ThiF family. This domain is found in ubiquitin activating E1 family and members of the bacterial ThiF/MoeB/HesA family. It is repeated in Ubiquitin-activating enzyme E1.	3.68064e-23
NC_019678.1|WP_015120901.1|6177291_6177882_+|HD-domain-containing-protein	gnl|CDD|379122	pfam13328, HD_4, HD domain. HD domains are metal dependent phosphohydrolases.	1.17425e-35
NC_019678.1|WP_044292273.1|6179546_6180551_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	3.09441e-105
NC_019678.1|WP_015120906.1|6191637_6192771_+|AAA-family-ATPase	gnl|CDD|379165	pfam13401, AAA_22, AAA domain.	1.79869e-05
NC_019678.1|WP_015120900.1|6175492_6177022_+|TIGR03985-family-CRISPR-associated-protein	gnl|CDD|274901	TIGR03985, hypothetical_protein_sll7078, CRISPR-associated protein, TIGR03985 family. Members of this protein family belong to CRISPR-associated (Cas) gene clusters. The majority of members are Cyanobacterial.	5.65075e-76
NC_019678.1|WP_015120905.1|6188914_6191641_+|DDE-type-integrase/transposase/recombinase	gnl|CDD|378037	pfam08722, Tn7_Tnp_TnsA_N, TnsA endonuclease N terminal. The Tn7 transposase is composed of proteins TnsA and TnsB. DNA breakage at the 5' end of the transposon is carried out by TnsA, and breakage and joining at the 3' end is carried out by TnsB. The N terminal domain of TnsA is catalytic.	4.05937e-08
NC_019678.1|WP_015120913.1|6197626_6198112_+|hypothetical-protein	gnl|CDD|373079	pfam14462, Prok-E2_E, Prokaryotic E2 family E. A member of the E2/UBC superfamily of proteins found in diverse bacteria. Analysis of the active site residues suggest that members of this family are inactive as they lack the characteristic catalytic residues of the E2 enzymes. They are usually fused to or in the neighborhood of a multi/poly ubiquitin domain protein. Other proteins of the ubiquitin modification pathway such as the E1 and JAB proteins are also found in its gene neighborhood along with a distinct predicted metal-binding protein.	0.000135461
NC_019678.1|WP_015120909.1|6195458_6195911_-|DUF4112-domain-containing-protein	gnl|CDD|379180	pfam13430, DUF4112, Domain of unknown function (DUF4112). This family has several highly conserved GD sequence-motifs of unknown function. The family is found in bacteria, archaea and fungi.	1.05827e-10

Protein sequences

>NC_019678.1|WP_015120907.1|6192760_6194158_+|helix-turn-helix-domain-containing-protein
MTVNLDTKNELWDLEPPSFLPRSRLFHLLPIGVGTPYVESLTSYVSRLAVAHSVSTGTLLAIEVGPLIKTNYSANRKSIVAIYGQESVRALNGIRLGALQLVRALETLTLRTDLQFLTMLPWTEVFPALGLLKHEQAWCPLCLEEWLENRKVIYLPLLWALNVVKVCPYHHQPLQSQCPHCHAQFLPLWRSSRPGYCLKCSGWLGSSKDARDVEPNFFEATDEFQWNIWAANTLGNLIAQAPSQHSPLPRETIKKALVFFVNKFSNGDVSAFGQLIGVPSSKITQWYSGKTIPTLDKLLKICYRLQISLIKFLQPELKQQVNTNQVTLCPSPQQRQLTVTSQRNKARIRSLLKSVLNQNEYPSPSVREVARRYHIGGATLYRYAPDLCQAISARYWDYKKLLQQQTIQQGINEVKRLTPELYAQGITPSVKNLASVMTNPEALWREEVLETLSEVRRSLGELPER
>NC_019678.1|WP_015120906.1|6191637_6192771_+|AAA-family-ATPase
MNKERPFPEELLLQSSQIKTSYFKSITVPHKKLKRALDTLLLNILEPADTLVFLVFGVTGVGKTTLRLRLEKLLSEEFIADIQSNPGQIAVAGLEAIPAERGNFSYKDYYTRALEALKEVLVEYKVNYGLTEPDSQELKHDYHINGKDSPALRRAMEKVFRYRQIKAFTVDEAQHLLMISGGHQMLQQMNWIKSIANLTGTIHILFGTYELLNCPTLNGQVGRRSEDIHLSPYYADQPEDVAEFIRVTNTFQRHLPLQKEPDLEKHYEYLLEGSVGCVGILKNWLTRSLRVALAESATTLTTSHLKQGAFGASRINKIRSEAQQGERRLLESEGLSFHLESSNVSNNQAVNKSSTKKGRVGQRNPKRDAVGMKQYDS
>NC_019678.1|WP_015120905.1|6188914_6191641_+|DDE-type-integrase/transposase/recombinase
MLSTQEFEEWCRRLKLPEVTRKVISQIRSTEPVRQVKSLGGNVSGNYCSQKMGKTLQFESHKVELPGIEEYETCSDVLEFYDQPYQLTLKFMTKKGREVTVTHIPDFFVIRQQSAGFEEWKPQAKLEKLSLLQPNRYVKNQDGQWTSPPAEEQAQLYGCYYRIRSDAEIDWIKYRNRQFLRSYAEQKYQIGTEIATFIKSLVSSQPGITYLKLLQYQNVNPDHINALLATEELYIDLSAAPLAEPEKVHIFRNQEMALAHNLTSVSQNLTVANSLQIIDVAVGTSFCWDGQPLTVLHNGESKIVLRSSNSLIHLTHSEFDLLVQRGEIVGLKVPEQIGIHPEAIERFLKASPQALAEANKRYLVIEPYLHGQKRENETVSLRTIRNWKAKFKAAEQKYCWGYIGLIDNHAAKGNRLPKISTEVWEFVDKIIESHYETLKQRGKLAVYGVLSQEWEKAGRIEHLPSYVTFSSRIKQRSGYQQTKKRLGSRAAYQKSNFYWELEFTTPRHGDRPFEICHIDHTQLDIELVCSRTGRTLGRPWATLLIDATSRRILAIYLTFDEPSYRSCMMVLRICVQRFSRFPETIVVDGGAEFGSTYFETLLAAFGCTKKQRPAAKARFGSVIERIFGTTNTEFFYNLRGNTQITKNVRVVTKSNNPKGQAVWTLDELYEHFCAYSYELYDCKEHPALLQSPRQAFLSGLALSGSRPHKKILYDQNFRIFTLPSTPKGTAKVQPSRGVKINYLYYWSVDDSFINPEVEGTNVPVRYDPFDMGTAYTYVKGQWVRCISDYYKSFHNCSEREVKLASLELHRSRQKVSQVITISAKEKAAYLESAEAKEVLLLQRLHDLARLDVHSIIEGERSGHNHPQNIALNQKNPELDTNFNSTKDESVILEHLNTIEPYKNEELWK
>NC_019678.1|WP_015120904.1|6180649_6180925_+|CRISPR-associated-endonuclease-Cas2
MLVVVVYDIPNDKRRTKLSNFLEGYGQRVQFSVFECFLNLDEMRQLFEKSKKIVKPSEDNVRFYWISEDAVSRVLTIGSEHPNAPPNYYVI
>NC_019678.1|WP_044292273.1|6179546_6180551_+|CRISPR-associated-endonuclease-Cas1
MAAIYLIEQGTNIYKDYQRFIIHVSEKPKLEVPIRDVQQIIVFGNIQLSTPVIQACLKEQIPVVFLSQTGTYHGHLWSEKSIHLDNQLVQAERRNDDLFRFSVSRAVVLGKLLNSKQLLMRFNRRRKIGKVEEAIYGINQDIDALNYVDNLDTLRGYEGIAAARYFPAFGNLITNPKFSFSQRFRQPPTDEINSLLSFGYTLLFNNVLSFIITEGLSPYIGHFHYGDKQKTYLAFDLMEEFRSPIVDSLVLKIINKSLFKPQDFDVVASTGGVYLSQTSRRVFLKQFENRMNEEISHPDLISQVTYRHAIQLQVRRYKRCLLSDNIYESFLRAD
>NC_019678.1|WP_015120902.1|6178419_6179382_+|Retron-type-reverse-transcriptase
MISSQFIDINNFQRAWEKVADKRGCAGVDGETISSFASNQTVNVYQLMNSVADGSYQPFPCKQVIIPKRNGSQRELKIPTIRDRIVQQALLNVISPLMEEKFSPVSFAYRPNLSYINAVEKIADWRDMGYVWVLDADIVKFFDNIDHHRLLQQVRLHIDHPGILCLIKAWISVGVETREGLILPQKGIPQGAVISPILANIYLHEFDEIISASDLEIVRYADDFLVLSTSQERIAIAKSQVIDLLDSLGLEINTDKTQITSFERGFRFLGHGFLSDAIFPVDTNKAKLKSGIETNREKTRTRKTSKKKLYHNPYRNKKVV
>NC_019678.1|WP_015120901.1|6177291_6177882_+|HD-domain-containing-protein
MNLNTTQKYFLTNRFEQALVYASRLHRKQIRKGSNIPYISHLLSVTALVLEDGGDEDEAIAALLHDAVEDQGGQATREVIFDMFGLKVAEIVDGCSDTNTIPKPPWLQRKQQYIDNLRGASASIRKVSLADKLHNARSILRDLSSNGESTWGKFKGGKEGTLWYYQTLLQLFLETNADSWMVQEFKRIVEQFSVNS
>NC_019678.1|WP_015120900.1|6175492_6177022_+|TIGR03985-family-CRISPR-associated-protein
MKREVFNYPPSVEVLKILTAGSLKQNLAKAVRIWVILRSIYGDESDEVKLELKEEFSFLEWRDLFFIDAKKYHQRDCIPNLHYVNQLNQNFIKEECRCAIKLKQWLFESSLRIDENHWCQSLKKYYSFEGDELNNLLQGGIAKNKSQHIQSEVKSLTVNKKFSKSLPEGRLFAVTGRNLKDNDFQSLVNLGWLNIKKYSGKVIYTKVNRFPEVFLSSLKNKEITSEQFTNHELSAFNNSLSQPINGIQRFFIHAEYIVHSSLNEHIELLQQKIKSLWKRDKVPLVKLNYRSAKLYQETIDCIVYPVCIYYYKRAPYLFAYGQIPQSNRKNPWSKIDWYDYRLDKIINLDELNKLDSNADNLDIPKHFLDKCYGKYPPNPDEIKDKMSAVWGFDIHKPQALLILRFDQYFYGNYIEGTERDDMFHKITRKQVEKLIKSYTPKASLEQKQLISTVQSRSEYDIYCKIDYRVDDNNIVMRLRAWCPNVEVIFPLDLRDRMRREMQEAYFMHR
>NC_019678.1|WP_015120899.1|6174985_6175342_-|hypothetical-protein
MSRFQERFNAKMKEWYDSDKSITKLFTTEYERMLAYLWACSEARKSEENIAEIKEFGRTNIKALGDSNYSQLLRTRDYCCRCGETYRLENLSICVECDNLFCYRCSRKKCGCGGEVVG
>NC_019678.1|WP_015120898.1|6174283_6174718_-|hypothetical-protein
MPFKFNHKYLVLITLLLFTNSCSAPKKSQAKLDAEFEQLLNQQIESRRGSTPKIREVFDKYIGKSEAKKIGNGICKSIKNSTFQKDIKAHWDKMSDLKREKKLSNRVMNDINASHVYIRTAAVNSYCPEYKVQIYKELAKTGEE
>NC_019678.1|WP_015120908.1|6194750_6195404_-|hypothetical-protein
MNKLIAGIAALALWTVSTGVANSQQVTRFKHQDDSYYHQRLNSKGIARYQYKIPANSFGVFTLKNHSRRSDFDIYVYDSSNGKLLTEGKSYGTKTELVITQPVGRDRYAYIKVLNYGSRTSRYKLYANYVNPGTKFLIAFAGIPFCSSARNINDRTSSRVITGISSMLQGSDFGGVARDVFINELTMEMRKQFGYGCMGEIAVNWVVSMAKGFYRNY
>NC_019678.1|WP_015120909.1|6195458_6195911_-|DUF4112-domain-containing-protein
MDINKSLPVKIQAHEANLIQTKHEIQKFIKMSEGLLFDQVGLDALIGAIPGVGGMYTGIMGIWLLLQSYKVRAENEDKLMIVALTFVDVVVGIVPIFGDIIDTFLRVHALNGSRLITHIDKQLSLIENTREQLNQGFNPDLSSLENLLLR
>NC_019678.1|WP_015120910.1|6196256_6196832_+|NYN-domain-containing-protein
MGNLHRVMIIADGDNAFMAAQSFNRKINWHKMRDYLADPKEGRELIEMVIYFGLPPAKDRFEEQRKSKEKFIYWAKSNGFLIVTKEGKAKGDGYENNVDVVMAIDAMELALEIKPDIVVLVTGDSDFAYLAQKLRRRGIRVEVASVEQSLGSELKNSANSVVDLTEVFDEFDPHNSNENFHRIGHANVFDA
>NC_019678.1|WP_015120911.1|6196874_6197222_+|hypothetical-protein
METVNGKLTNQKLNQFDEITHNIEYINRRCEYLQSQLTHISSQDNLQYLQKLEQRIGFLEELTSKQSKQISFIKIGSIIALLFVWSISGMNNQQKDDNTQLPKQVYSYIAPFSTD
>NC_019678.1|WP_015120912.1|6197382_6197601_+|hypothetical-protein
MRAIVNGKLVDLPKGATVEELRKKLPEIGQDDVMEEGFGGTRPLKSNEALKEGSKVWTVPKIVKGSDKSSKK
>NC_019678.1|WP_015120913.1|6197626_6198112_+|hypothetical-protein
MAITISKDKSGFKPSSRIIEELKLLEKVAKNIIVGSKTVGDTRYTAVLIKGMPLSSQKFKVSNTDVLFLLPSDYPRLPPIGCYLNYPWNTVGEGDHHFTRQSYYGAPFLSEQGWYWYCVGLGGGFNHDVWLNSWRPSNNAENGHNLTTLFVTARHAINSDD
>NC_019678.1|WP_157229455.1|6198339_6199731_+|ThiF-family-adenylyltransferase
MWSDFQKSMLSSRMFNEEVIGFLFCQRHQVSKRKVRYIPKTWVVPTSECYEHQSTDGLVLTQRFHSYLLENHLFPGLDIVHIHTHAGVGIPEFSYVDNRYESEYAKFIASHFPEKPRLVSGVFDEGLDNCKFRIWDRKGREFQQVDFCNSLFEISDSENIFDNPNLMFARQKTFGETNQKTLNQLKVGLIGCGGIGSIFAELLGRLGVKNWVLVDPDKLEQVNLNRMTGATQEMVEHGWYKVHYVKHLIKKIYACGSHVKTISTAIEAETATQEIANCDLIVVATDNHLSRKTAQEVALKYMRPLVCLGTHIDVKPDGTPRMYCRITVPPLGGDWCLMCGNIINLQRAALESAPSEINHMAENAGYLEGVNDPSVFWLNSICASTAVGVIHGIVSGFMNVDSGIDWIYEFPGSEWRKTDTTYLQTDDCYFCGLNSSENLVQESDYESPDFEEQDFDNSDFIVW
>NC_019678.1|WP_015120916.1|6200523_6202047_-|hypothetical-protein
MARSKTPSFVTEISLKVDSKQEKELSSRFQAARQLYNACLNEALVRMNLVKNSELYQQAKKLRGGDKKKRQDLFNKARETHRLSDYALKTFATQTANRSKWISSNLGAHEKQTIGTRAFKAVDRILFGQAKKVRFKVTTRFKSVEGQSNATGIRFINNQVLWKKLILNPIIDWNNPVIVHGLNSPIKYCRILWRNLNGKKRWFIQLINEGLPYQKPQNYVIKGIVGLDVNIAAVAFVADKKAGLLPFAEKVPTFEREIKALQRKMQRSQRMHNPDNFEPDFDKKVGNRIVRKKGKVKKGKKQWIKTKNYRRIQVRKAELERRKASYAKSQNRKLVNEILRHGNQIKTERVSIKGWQKIYGKAISAKSPGYFQSELKRKAENAGGYFLTFSTQTTALSQTHLDGTRIKKKLSERVHRDVTGIQPMHRDLFSAFLSRCVYNNKLSLWDAQCEYPGTEPFLLDGWQQSQSANRVAERESRNSYSSSEQMSNEALTSNQISQKDYKLEGNA
>NC_019678.1|WP_157229320.1|6202159_6202327_+|hypothetical-protein
MTNRKQSLTAQVAIRLTPQVKEKLKNIPNWQNQVRDFIEDMTKDDGVSKACPKDI
>NC_019678.1|WP_015120918.1|6202967_6203957_+|hypothetical-protein
MQSYQIELKGDVLHVGFNRNVPAQGDRIAKDALERITQMIDSGEISGGKRILIDGPQSVPVAYILSHKLVHLYQAVAVLDPKLGSKISTADGAIRHKTYIVTSVHGSTEYKVGDLIETQESQKERSRIKVVLCGPPQSGKSCLRDGLKRAILANVNAPYPYIITACPDGEGSWHQEACENNESLASECKRKNKGDVTPEFAEEAARWVKSANQLINIIDVGGKITDENKKIMQPATHAVILSGDTSKFAGWEGFCQILGLKIIAKIHSQLNAVQDEVLFSKNWRENTNELLQTNPIVTGSVHSLKRGENLSTRPMVQALADVLIHLTKC

Crispr_ID: NC_019678_28

• CRISPR_ID: NC_019678_28
• CRISPR_location: 6212788-6213336
• CRISPR_type: TypeIII
• Repeat_type: A:N
• Spacer_info: 7 spacers
• Cas_protein_info: csm6,cmr5gr11,cmr4gr7,cmr3gr5,cas10,csx3

Consensus repeat of NC_019678_28

Consensus_repeat	Method
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	CRISPRCasFinder
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	CRT
CTTCCGCCGACTGGATTAAGTCGGATTAGTTGGAAAC	PILER-CR

spacers of NC_019678_28

>28.1|6212825|37|NC_019678|CRISPRCasFinder,CRT
ATGACCCAATCGAACCAAGCGACATCCCAGAATACAA
>28.2|6212899|37|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TTGCTGTCAATTTCTGACAAATTGCAAAATGTAACTA
>28.3|6212973|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AACCAATCCTCCAAACCAAGATAGTAAAGACTCTT
>28.4|6213045|37|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TTAAGTCTTCCTGAAAACTCGAATGCAGACTTAGCAG
>28.5|6213119|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TCTTTAACTACGCTCACTAAAGAAGTAGACAGCAA
>28.6|6213191|37|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AACTCTCAATATAAGATATTGTCATTGAACTAAAAAA
>28.7|6213265|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR
CCTTAGCATAATTCTCAAGAGAATCTGCCATTTGA

CRISPR arrays and Neighbor proteins around NC_019678_28

CRISPR arrays

The CRISPR arrays of NC_019678_28

>merge|NC_019678|28|6212788-6213336|CRISPRCasFinder,CRT,PILER-CR
TTATTCAACTAATTCGACTTAATCCAGTCGGCGGAAGATGACCCAATCGAACCAAGCGACATCCCAGAATACAAGTTTCCAACTAATCCGACTTAATCCAGTCGGTGGAAGTTGCTGTCAATTTCTGACAAATTGCAAAATGTAACTAGTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAGAACCAATCCTCCAAACCAAGATAGTAAAGACTCTTGTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAGTTAAGTCTTCCTGAAAACTCGAATGCAGACTTAGCAGGTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAGTCTTTAACTACGCTCACTAAAGAAGTAGACAGCAAGTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAGAACTCTCAATATAAGATATTGTCATTGAACTAAAAAAGTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAGCCTTAGCATAATTCTCAAGAGAATCTGCCATTTGAGTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG

>NC_019678|28|25|6212788-6213336|CRISPRCasFinder
TTATTCAACTAATTCGACTTAATCCAGTCGGCGGAAG	ATGACCCAATCGAACCAAGCGACATCCCAGAATACAA
GTTTCCAACTAATCCGACTTAATCCAGTCGGTGGAAG	TTGCTGTCAATTTCTGACAAATTGCAAAATGTAACTA
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	AACCAATCCTCCAAACCAAGATAGTAAAGACTCTT
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	TTAAGTCTTCCTGAAAACTCGAATGCAGACTTAGCAG
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	TCTTTAACTACGCTCACTAAAGAAGTAGACAGCAA
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	AACTCTCAATATAAGATATTGTCATTGAACTAAAAAA
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	CCTTAGCATAATTCTCAAGAGAATCTGCCATTTGA
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG

>NC_019678|28|11|6212788-6213336|CRT
TTATTCAACTAATTCGACTTAATCCAGTCGGCGGAAG	ATGACCCAATCGAACCAAGCGACATCCCAGAATACAA
GTTTCCAACTAATCCGACTTAATCCAGTCGGTGGAAG	TTGCTGTCAATTTCTGACAAATTGCAAAATGTAACTA
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	AACCAATCCTCCAAACCAAGATAGTAAAGACTCTT
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	TTAAGTCTTCCTGAAAACTCGAATGCAGACTTAGCAG
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	TCTTTAACTACGCTCACTAAAGAAGTAGACAGCAA
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	AACTCTCAATATAAGATATTGTCATTGAACTAAAAAA
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	CCTTAGCATAATTCTCAAGAGAATCTGCCATTTGA
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG

>NC_019678|28|12|6212862-6213336|PILER-CR
GTTTCCAACTAATCCGACTTAATCCAGTCGGTGGAAG	TTGCTGTCAATTTCTGACAAATTGCAAAATGTAACTA
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	AACCAATCCTCCAAACCAAGATAGTAAAGACTCTT
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	TTAAGTCTTCCTGAAAACTCGAATGCAGACTTAGCAG
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	TCTTTAACTACGCTCACTAAAGAAGTAGACAGCAA
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	AACTCTCAATATAAGATATTGTCATTGAACTAAAAAA
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG	CCTTAGCATAATTCTCAAGAGAATCTGCCATTTGA
GTTTCCAACTAATCCGACTTAATCCAGTCGGCGGAAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015120934.1|6221067_6221463_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120925.1|6211553_6212693_+|hypothetical-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	gnl|CDD|187873
NC_019678.1|WP_015120933.1|6220065_6220923_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_157229321.1|6217944_6218208_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120923.1|6209234_6209627_+|hypothetical-protein	cmr5gr11	mkCas0065_cmr5gr11_CAS-III-B	unknown
NC_019678.1|WP_015120924.1|6209849_6211526_+|hypothetical-protein	unknown	unknown	gnl|CDD|213662
NC_019678.1|WP_015120928.1|6216316_6216949_-|hypothetical-protein	unknown	unknown	gnl|CDD|287956
NC_019678.1|WP_157229457.1|6218411_6218606_+|hypothetical-protein	unknown	unknown	gnl|CDD|369567
NC_019678.1|WP_157229320.1|6202159_6202327_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120926.1|6213595_6214321_-|CRISPR-associated-protein	unknown	unknown	gnl|CDD|187878
NC_019678.1|WP_044291158.1|6204847_6205129_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120936.1|6222410_6223028_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NC_019678.1|WP_015120920.1|6205328_6207194_+|CRISPR-associated-protein	cas10	cd09679_cas10_CAS-III	gnl|CDD|187810
NC_019678.1|WP_015120921.1|6207181_6208324_+|CRISPR-associated-protein-(Cas_Cmr3)	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	gnl|CDD|370625
NC_019678.1|WP_015120918.1|6202967_6203957_+|hypothetical-protein	csx3	mkCas0115_csx3_CAS-I:CAS-III	unknown
NC_019678.1|WP_015120935.1|6221462_6221888_+|HNH-endonuclease	unknown	unknown	gnl|CDD|366837
NC_019678.1|WP_015120932.1|6218980_6219463_+|endonuclease	unknown	unknown	gnl|CDD|198380
NC_019678.1|WP_015120922.1|6208422_6209232_+|hypothetical-protein	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl|CDD|224255
NC_019678.1|WP_157229456.1|6217151_6217316_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120916.1|6200523_6202047_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019678.1|WP_015120925.1|6211553_6212693_+|hypothetical-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	1.2e-46	153.0	0.0
NC_019678.1|WP_015120920.1|6205328_6207194_+|CRISPR-associated-protein	cas10	cd09679_cas10_CAS-III	2.7e-25	83.8	12.3
NC_019678.1|WP_015120921.1|6207181_6208324_+|CRISPR-associated-protein-(Cas_Cmr3)	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	1.9e-17	58.6	0.5
NC_019678.1|WP_015120918.1|6202967_6203957_+|hypothetical-protein	csx3	mkCas0115_csx3_CAS-I:CAS-III	3.5e-116	381.9	0.2
NC_019678.1|WP_015120922.1|6208422_6209232_+|hypothetical-protein	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	5.9e-26	86.3	0.0
NC_019678.1|WP_015120923.1|6209234_6209627_+|hypothetical-protein	cmr5gr11	mkCas0065_cmr5gr11_CAS-III-B	1.2e-68	223.6	5.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015120936.1|6222410_6223028_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	2.85728e-32
NC_019678.1|WP_015120925.1|6211553_6212693_+|hypothetical-protein	gnl|CDD|187873	cd09742, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems; also known as APE2256 family.	4.40444e-48
NC_019678.1|WP_015120920.1|6205328_6207194_+|CRISPR-associated-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	9.2001e-21
NC_019678.1|WP_015120932.1|6218980_6219463_+|endonuclease	gnl|CDD|198380	cd00719, GIY-YIG_SF, GIY-YIG nuclease domain superfamily. The GIY-YIG nuclease domain superfamily includes a large and diverse group of proteins involved in many cellular processes, such as class I homing GIY-YIG family endonucleases, prokaryotic nucleotide excision repair proteins UvrC and Cho, type II restriction enzymes, the endonuclease/reverse transcriptase of eukaryotic retrotransposable elements, and a family of eukaryotic enzymes that repair stalled replication forks. All of these members contain a conserved GIY-YIG nuclease domain that may serve as a scaffold for the coordination of a divalent metal ion required for catalysis of the phosphodiester bond cleavage. By combining with different specificity, targeting, or other domains, the GIY-YIG nucleases may perform different functions.	5.20672e-09
NC_019678.1|WP_015120921.1|6207181_6208324_+|CRISPR-associated-protein-(Cas_Cmr3)	gnl|CDD|370625	pfam09700, Cas_Cmr3, CRISPR-associated protein (Cas_Cmr3). CRISPR is a term for Clustered Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This highly divergent family, found in at least ten different archaeal and bacterial species, is represented by TM1793 from Thermotoga maritima.	4.3242e-06
NC_019678.1|WP_015120935.1|6221462_6221888_+|HNH-endonuclease	gnl|CDD|366837	pfam01844, HNH, HNH endonuclease. His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity.	3.8398e-10
NC_019678.1|WP_015120924.1|6209849_6211526_+|hypothetical-protein	gnl|CDD|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	0.000105141
NC_019678.1|WP_015120928.1|6216316_6216949_-|hypothetical-protein	gnl|CDD|287956	pfam11043, DUF2856, Protein of unknown function (DUF2856). Some members in this viral family of proteins with unknown function are annotated as Abc2 however this cannot be confirmed.	0.00566423
NC_019678.1|WP_157229457.1|6218411_6218606_+|hypothetical-protein	gnl|CDD|369567	pfam07878, RHH_5, CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5. This family contains bacterial proteins that form a ribbon-helix-helix fold. This fold occurs in many examples of bacterial antitoxins.	5.5407e-06
NC_019678.1|WP_015120922.1|6208422_6209232_+|hypothetical-protein	gnl|CDD|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	5.20411e-23
NC_019678.1|WP_015120926.1|6213595_6214321_-|CRISPR-associated-protein	gnl|CDD|187878	cd09747, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as Cas02710 family.	0.000305781

Protein sequences

>NC_019678.1|WP_015120925.1|6211553_6212693_+|hypothetical-protein
MRRVILSTIGTSLLTNQINRANPEEKDWYPQLRDTANLNEQDTPETVKNIISTLEDRANKQLDKVQIPQIRRASAELNGIYGVYQEDLTQGKEDYHFLIATDTIQGKTTAEIVENFLRKQGLTNTSIYAPSGLSTISTEAFSVGIDELIVWLQETIPPLRESKYKICFNLVGSFKSLQGYLNTIGMFYADEIIYIFEGQKSDLITIPRLPISVDISSLKPYTMQLALLNAGAGLSPQETNGIPETMLGEVDGKMTLSTWGYLVWNQCKDDLLSGDLINFSRLEYQDSFRADYNRVKEKHKRVKLQETLANVTRLLNESNGDTAILKQHGGIKYDKYTNKGNIDHFRVTQSVRVTCVSSQGKLNLYHYGEQHDDINNNPY
>NC_019678.1|WP_015120924.1|6209849_6211526_+|hypothetical-protein
MNIPEPAKKVPMLFRAQIDGRCQIQRLVPRREEQDATRWASEWVEKTYPQLRESAGFVQTRTYNLTWRFITNSGQDDGVTRPVIGARGWPFYPGSSMKGIFRRACSQEEAERYCGKSLNDDFKPGILRFHGGYPTDTAWTEDLVDIVHPQQDFQVKSNKKDSGAFIQISLHQPELKFGISSTVPLDDQEWEVIWNIWEKAISTGIGSRVCAGYGQPEKHTGNVLYRTKLKGQGQAAKLIDGTGEFRANVFRAAVRGHALRIFGGLTNADTADRIVNNLFGGIKGQAVIGLLGMSFRVLTDNPGEFGRKGYLQPTYDIEGELTWLLARKLPNSEQELALKKLIGALTRFAMIFGGFGKSWRRADHRLFYEEYYENQYKSLIGCHWQWLGERSLANDVKVRKLDHVTKFIAEIQQIAKEWMRLQNITPNPAQKAAWRETWHQDNVQIWGREAENKEDSRAIFWLHKPYQEEIRGIQSEGSIYRSSVTGQMGQIGRLWHRMYPFVRLVKNPEDPKGKPIPKKTFRYLEFLTLFPDNSRESQDFIKFLNSQQNRSNSFQKLW
>NC_019678.1|WP_015120923.1|6209234_6209627_+|hypothetical-protein
MGWKSYDLDREAQKLVLSAKNRDDKSLNQSYKMRMAVAYGLERFWGEHLRLQAKEPQKSQYWKETWDALVGIMEQAGVLIPNEPVNANNVGQIQAMSEQLWQLEIQEQRVSLAVLTQLCDCIVWWTQRYK
>NC_019678.1|WP_015120922.1|6208422_6209232_+|hypothetical-protein
MYHKAYGIIETLAPLHIGASAGEETGNLNLIFRDQFTQTGIIPGSSIRGRFRADMRPNSKDNERKWYGHEAISGEENKTTEALIKFEYASLVWLPVFCPGQPIVWITCPRLLKRYKQIASISAEIPKPYSAPKALQSRQVGTNHRVLFFNLGFIEIEHDDNLTDWIPSGTDFNRDNLLVVADNDIAMLHDMALYRQSRVKLADSEKKVEGGAFFNVEALPEGSVLVFPIALKETGWQPFGDSTESQDLYFGGLESIGFGHCRVKLAGDY
>NC_019678.1|WP_015120921.1|6207181_6208324_+|CRISPR-associated-protein-(Cas_Cmr3)
MSAVETSSNTSEQTKYLPPRSPFTHLIIIEPLGLLYGSSGRFLSPENLVGRSGSNFPPTAATLSGLFAASQNENADIRDLMLAGPFWGDVDELTSSEQNFYVPTPKNCLVKDGKIVDKLSWNRELEAWRNKDNETPVDKYDNNTWLAINNWNNPEEVKKNPWKFLAHLHPRLELEERHVIRNHEEQGSLFLENSVQMETGTCLVYLSNTKLEPGWYRFGGEGHMVDVRCEPLSQSLSELLNKPVGKKFALITPAVWGSNRLSKRVPVCLEKRDQTFYQQEQPIPENQEKNVWELEALFTSRPIPFRYRLGNRENENQQENKHPFQPPKLLSRGRYAVPAGTVYILKEPINQPWQEWNPNWFPREGPSLKRWGCGLALPLE
>NC_019678.1|WP_015120920.1|6205328_6207194_+|CRISPR-associated-protein
MTNKIYTVITFAPVQGFIEKSRKLRDLYGSSYLLSYISWVICNAAENHGCTVISPASINVTQGMPNQIIIEGNFPKGEAQSVLLEAWKCITETCREWIETNVEVIEGKKVDYTPWRRTWGLWTKYAWEFFWVQGNEKQSISDVREKLNEKKRARDWTGINWQGESSTLSGADGIAYPKLGFNSDPREYNYQQEKNDVRAFYQALSEKLGESFIKSVRLKVPDEKMSERSQEYGKSFIDPDEELSVPELIKRLITHNVISEKLTERLKNVFGNNGIILKNLAQQINQLSDDLNPTTFKDLSRFKDNLYTGWFQGDGDKAGEFLKSFANTPEEAQETHKFSEEMREWGSYFQELPKNHEMKNWRVIYAGGDDFLGAFYNRKNANDCVNFFSKFKSDTWNQPEPKKITVSVGFVWASANIPQRDILQHCREAEKSAKSSGRDRIAFRILFNNGNNLEWVCSWRLLEEGLLSSYRDREGGQNWTHIYNDVAVLESRHAFDNHGLSVGLGLLEIYFPAYLDVIKNKSKQLQPKYLDLIETIAEILGKESIYYKEVIEVIEELEELEADKLNKASTNWIINLARKILGEKDNYYKENTEELDPDKLNKALTDWIINLAKVGFHLCQQ
>NC_019678.1|WP_044291158.1|6204847_6205129_+|hypothetical-protein
MQGGFMPLSALVCWVVIIILVIFFQPEKISQLNLEYFVNILIGGSGTLSGINIIYKVSNSPHLRNLLGYDAFTVFIGASVVIWMSIQQMLKPF
>NC_019678.1|WP_015120918.1|6202967_6203957_+|hypothetical-protein
MQSYQIELKGDVLHVGFNRNVPAQGDRIAKDALERITQMIDSGEISGGKRILIDGPQSVPVAYILSHKLVHLYQAVAVLDPKLGSKISTADGAIRHKTYIVTSVHGSTEYKVGDLIETQESQKERSRIKVVLCGPPQSGKSCLRDGLKRAILANVNAPYPYIITACPDGEGSWHQEACENNESLASECKRKNKGDVTPEFAEEAARWVKSANQLINIIDVGGKITDENKKIMQPATHAVILSGDTSKFAGWEGFCQILGLKIIAKIHSQLNAVQDEVLFSKNWRENTNELLQTNPIVTGSVHSLKRGENLSTRPMVQALADVLIHLTKC
>NC_019678.1|WP_157229320.1|6202159_6202327_+|hypothetical-protein
MTNRKQSLTAQVAIRLTPQVKEKLKNIPNWQNQVRDFIEDMTKDDGVSKACPKDI
>NC_019678.1|WP_015120916.1|6200523_6202047_-|hypothetical-protein
MARSKTPSFVTEISLKVDSKQEKELSSRFQAARQLYNACLNEALVRMNLVKNSELYQQAKKLRGGDKKKRQDLFNKARETHRLSDYALKTFATQTANRSKWISSNLGAHEKQTIGTRAFKAVDRILFGQAKKVRFKVTTRFKSVEGQSNATGIRFINNQVLWKKLILNPIIDWNNPVIVHGLNSPIKYCRILWRNLNGKKRWFIQLINEGLPYQKPQNYVIKGIVGLDVNIAAVAFVADKKAGLLPFAEKVPTFEREIKALQRKMQRSQRMHNPDNFEPDFDKKVGNRIVRKKGKVKKGKKQWIKTKNYRRIQVRKAELERRKASYAKSQNRKLVNEILRHGNQIKTERVSIKGWQKIYGKAISAKSPGYFQSELKRKAENAGGYFLTFSTQTTALSQTHLDGTRIKKKLSERVHRDVTGIQPMHRDLFSAFLSRCVYNNKLSLWDAQCEYPGTEPFLLDGWQQSQSANRVAERESRNSYSSSEQMSNEALTSNQISQKDYKLEGNA
>NC_019678.1|WP_015120926.1|6213595_6214321_-|CRISPR-associated-protein
MQNSFFQVAKRFFNPETLIPFLIGAIFLSVLGNAITDILKAIIGDTTPDTVKIAIGSVLIFMFCVWFVTKSITTNLPPIDLGKSSPGKHKGLILLVSREEPCRKAIEHHLPELKYCWLICSSQSLNVAKKLQQDFPKLIIPEPLVIKDVYDPVEFSQVVMNVYDCLPSRWTKDDIIADFTGMTAQGSVGMTIASLLMRQSRLQYTPAESRDGKPTGNSLNPIEIALTEKRLARSKKLKEIH
>NC_019678.1|WP_015120928.1|6216316_6216949_-|hypothetical-protein
MKNCEILKSLPQQGLEPRQFLRHCFGIAELTASELLEEETDSQYRKKCITVFCTIFNIQRATVRKWGSDLNFEGMPKYCRISLAYIYAAQIAPPQLGSILKGDFVPPSVDAQTFLEKVLLDELTEQEILQTVSHANFRGTCVKTLTDVLQIGTKSVQDWGQDMSFRKMPRIHKHTLGYALAAISQVSLTDVFLKASKPAAAVSKALSTAA
>NC_019678.1|WP_157229456.1|6217151_6217316_+|hypothetical-protein
MKNTEDKTVKLVVFLSDDERTQFKIACARSKTSMSQKAKELILAWVESEEEQSS
>NC_019678.1|WP_157229321.1|6217944_6218208_+|hypothetical-protein
MSKLQVETMPLEENVRLNITVSRYNLQRLKYWAAISGKTPSAYASQIISARLEANFDLINRQLEDLAQSKGIEMSDLKELLDDQDSK
>NC_019678.1|WP_157229457.1|6218411_6218606_+|hypothetical-protein
MRLTVTKRISVSIPDLTHEKLQTWADIEGTSLADLAAYLLRRDIEIAEKEGKLRYPDEQNSNSE
>NC_019678.1|WP_015120932.1|6218980_6219463_+|endonuclease
MNTQLIDPFKLPTISLSQRKHLPLVCAVYFVLHDNKVVYVGKATVLRQRWDSHHRIKEFKNLPGEVRIAWHKSDSPELIDELEKSMIACFKPSMNGSKVEYATPRKTIYLEPKTMEALKQRANKEKRTVSNLCNLLIEQEMSEWLKLEKTSDAKTEKYSQ
>NC_019678.1|WP_015120933.1|6220065_6220923_+|hypothetical-protein
MSKQQFEQNPKLPPKRGRPVDMQKDRVTFHINVDTRTQIEKLIPEWGKSLSMVVRKLVNLGLEVVSLSNKGITPRSGNLEDWLASYTSLGTELTIACETLNLSVPKSGQVAIWLLDKMAFGSNDPHVISEELNTTPNLLERIRLGKQVQTFSFKQGLELPQNEEFLTWLEQLYDNALIGQEFVTTCQTLGLQPPQKGEIEEWLLLKMGQHPQLEQSNVAEADSTAQSQSTEDDLLGVNSQPFLEYLLTLDKMPTEEEQFLIASRFGVESTHLTKLISRMMFEEKG
>NC_019678.1|WP_015120934.1|6221067_6221463_+|hypothetical-protein
MSILKVEVQLSSEELLKAVEQLNLSELEQFVSQVIVLKAQRKATRLPQTEAELLLKINQGIPDNIHKDYEELKVKREEETLTGDEYQRLLQLTEEIEKIQAQRIENLAELARLRGVSLTALMENLGIHATK
>NC_019678.1|WP_015120935.1|6221462_6221888_+|HNH-endonuclease
MSDSRVKAQLKKSVVKRANGCCEYCRSQESFAIQAFSAEHIIPKSKGGETNLSNLALSCQGCNNHKYNKIQGYDPVSGETVPLYHPRQQLWNDNFAWNNDFTLVIGLNPIGRATVETLKLNREGVVNLRRVLFAMGEHPPS
>NC_019678.1|WP_015120936.1|6222410_6223028_-|Uma2-family-endonuclease
MTITPSKLLTFEEFIDWLPQNSAKRYELHDGIIVEMAQPTGKHEKVTGLLAGEVCIEYKRLKLPYFIPKTALVKPPNKSSGYLPDIVLINDANLDNEPLWEKESTVIHSVSIPLIVEVVSTNWEDDYYTKFGNYQAMKIPEYWIADYAALGGRKFIANPKQPTFFVCELIDDEYQMTAFRGDERIISPTFPKLNLTAQQVFDAIV

Crispr_ID: NC_019678_29

• CRISPR_ID: NC_019678_29
• CRISPR_location: 6307708-6307948
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 3 spacers

Consensus repeat of NC_019678_29

Consensus_repeat	Method
TCTTTTCAACCCGCCTAAAGCTT	CRISPRCasFinder

spacers of NC_019678_29

>29.1|6307731|50|NC_019678|CRISPRCasFinder
GAAGAAGTGTTAAAACGATGAATTCTCCAACCAAAGCCACTGGTAATAGG
>29.2|6307804|49|NC_019678|CRISPRCasFinder
GAAGAAGTGTTGAAACAGCGAGCTACAGTTCGTAAATGGGGAAGCGACC
>29.3|6307876|50|NC_019678|CRISPRCasFinder
GAATGAGCCTTGAAACGGAGTGACTCCGCCTTAAACAATTACTTAAGGAT

CRISPR arrays and Neighbor proteins around NC_019678_29

CRISPR arrays

The CRISPR arrays of NC_019678_29

>merge|NC_019678|29|6307708-6307948|CRISPRCasFinder
TTTTTTCAACCTACTTAAAACTTGAAGAAGTGTTAAAACGATGAATTCTCCAACCAAAGCCACTGGTAATAGGTGCTTTCAACCCGCTCAAAATTTGAAGAAGTGTTGAAACAGCGAGCTACAGTTCGTAAATGGGGAAGCGACCTCTTTTCAACCCGCCTAAAGCTTGAATGAGCCTTGAAACGGAGTGACTCCGCCTTAAACAATTACTTAAGGATTCTTTTCAACCCGCCCAAAGCTT

>NC_019678|29|26|6307708-6307948|CRISPRCasFinder
TTTTTTCAACCTACTTAAAACTT	GAAGAAGTGTTAAAACGATGAATTCTCCAACCAAAGCCACTGGTAATAGG
TGCTTTCAACCCGCTCAAAATTT	GAAGAAGTGTTGAAACAGCGAGCTACAGTTCGTAAATGGGGAAGCGACC
TCTTTTCAACCCGCCTAAAGCTT	GAATGAGCCTTGAAACGGAGTGACTCCGCCTTAAACAATTACTTAAGGAT
TCTTTTCAACCCGCCCAAAGCTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015120992.1|6306037_6306958_-|hypothetical-protein	unknown	unknown	gnl|CDD|341491
NC_019678.1|WP_015120993.1|6309485_6309932_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133380
NC_019678.1|WP_044291165.1|6303833_6304058_+|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl|CDD|224638
NC_019678.1|WP_015120991.1|6305267_6306041_-|HIRAN-domain-containing-protein	unknown	unknown	gnl|CDD|214906
NC_019678.1|WP_015120997.1|6316068_6316410_+|M48-family-metallopeptidase	unknown	unknown	gnl|CDD|320703
NC_019678.1|WP_015120990.1|6304083_6305139_-|hypothetical-protein	unknown	unknown	gnl|CDD|227198
NC_019678.1|WP_015121001.1|6318425_6319595_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_157229458.1|6310104_6311646_+|N-6-DNA-methylase	unknown	unknown	gnl|CDD|223363
NC_019678.1|WP_044291163.1|6302472_6302697_-|reverse-transcriptase-like-protein	unknown	unknown	gnl|CDD|260011
NC_019678.1|WP_015120998.1|6316575_6317361_+|TIGR04255-family-protein	unknown	unknown	gnl|CDD|275082
NC_019678.1|WP_015121002.1|6319704_6320022_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120988.1|6302888_6303413_-|reverse-transcriptase-like-protein	unknown	unknown	gnl|CDD|260011
NC_019678.1|WP_015120985.1|6298294_6300127_+|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173810
NC_019678.1|WP_015121000.1|6317769_6318363_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120989.1|6303590_6303830_+|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl|CDD|224514
NC_019678.1|WP_015120996.1|6312934_6316072_+|HsdR-family-type-I-site-specific-deoxyribonuclease	unknown	unknown	gnl|CDD|273028
NC_019678.1|WP_015120999.1|6317365_6317761_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015120995.1|6311648_6312938_+|restriction-endonuclease-S-subunit	unknown	unknown	gnl|CDD|341150
NC_019678.1|WP_157229324.1|6300398_6300836_+|protease-complex-subunit-PrcB-family-protein	unknown	unknown	gnl|CDD|379569
NC_019678.1|WP_015120987.1|6300908_6302408_+|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|130902

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015120992.1|6306037_6306958_-|hypothetical-protein	gnl|CDD|341491	cd17792, CtkA, serine/threonine-protein kinase CtkA and similar proteins. The Helicobacter pylori serine/threonine-protein kinase CtkA (proinflammatory kinase), encoded by the jhp940 gene, has been shown to be secreted by the bacterium and to induce cytokines in gastric epithelial cells. It may play a role in chronic gastric inflammation. CtkA autophosphorylates itself at a threonine residue near the N-terminus and it translocates into cultured human cells. It also enhances phosphorylation of the NF-kappaB p65 subunit at Ser276 in human epithelial cancer cells; phosphorylation at this position is known to activate the transcriptional activity of NF-kappaB.	1.39475e-12
NC_019678.1|WP_015120993.1|6309485_6309932_+|MerR-family-transcriptional-regulator	gnl|CDD|133380	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators. Helix-turn-helix (HTH) transcription regulator GlnR and related proteins, N-terminal domain. The GlnR and TnrA (also known as ScgR) proteins have been shown to regulate expression of glutamine synthetase as well as several genes involved in nitrogen metabolism. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	3.41983e-14
NC_019678.1|WP_044291165.1|6303833_6304058_+|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl|CDD|224638	COG1724, COG1724, Predicted RNA binding protein (dsRBD-like fold), HicA family [General function prediction only].	2.21029e-20
NC_019678.1|WP_015120991.1|6305267_6306041_-|HIRAN-domain-containing-protein	gnl|CDD|214906	smart00910, HIRAN, The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p. HIRAN is found as a standalone protein in several bacteria and prophages, or fused to other catalytic domains, such as a nuclease of the restriction endonuclease fold and TDP1-like DNA phosphoesterases, in the eukaryotes. It has been predicted that this protein functions as a DNA-binding domain that probably recognises features associated with damaged DNA or stalled replication forks.	3.60961e-11
NC_019678.1|WP_015120997.1|6316068_6316410_+|M48-family-metallopeptidase	gnl|CDD|320703	cd07344, M48_yhfN_like, Peptidase M48 YhfN-like, a novel minigluzincin. M48 YhfN-like protease is considered as a CaaX prenyl protease 1 homolog, with most of the sequences in this family as yet uncharacterized. It contains the zinc metalloprotease motif (HEXXH), likely exposed on the cytoplasmic side. It is probably associated with the endoplasmic reticulum (ER), regardless of whether its genes possess the conventional signal motif (KKXX) in the C-terminal. Proteins in this family proteolytically remove the C-terminal three residues of farnesylated proteins. This novel family of related proteins consist of the soluble minimal scaffold similar to the catalytic domains of the integral-membrane metallopeptidase M48 and M56, thus called minigluzincins.	1.5429e-33
NC_019678.1|WP_015120990.1|6304083_6305139_-|hypothetical-protein	gnl|CDD|227198	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown].	2.21819e-17
NC_019678.1|WP_157229458.1|6310104_6311646_+|N-6-DNA-methylase	gnl|CDD|223363	COG0286, HsdM, Type I restriction-modification system methyltransferase subunit [Defense mechanisms].	1.91321e-92
NC_019678.1|WP_044291163.1|6302472_6302697_-|reverse-transcriptase-like-protein	gnl|CDD|260011	cd09279, RNase_HI_like, RNAse HI family that includes archaeal, some bacterial as well as plant RNase HI. Ribonuclease H (RNase H) is classified into two evolutionarily unrelated families, type 1 (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type 2 (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner. RNase H is involved in DNA replication, repair and transcription. RNase H is widely present in various organisms, including bacteria, archaea and eukaryotes and most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology, type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site (DEDD) residues and have the same catalytic mechanism and functions in cells. One of the important functions of RNase H is to remove Okazaki fragments during DNA replication. Most archaeal genomes contain only type 2 RNase H (RNase HII); however, a few contain RNase HI as well. Although archaeal RNase HI sequences conserve the DEDD active-site motif, they lack other common features important for catalytic function, such as the basic protrusion region. Archaeal RNase HI homologs are more closely related to retroviral RNase HI than bacterial and eukaryotic type I RNase H in enzymatic properties.	9.717e-11
NC_019678.1|WP_015120998.1|6316575_6317361_+|TIGR04255-family-protein	gnl|CDD|275082	TIGR04255, hypothetical_protein, TIGR04255 family protein. Members of this uncharacterized protein family are found broadly but sporadically among bacteria and archaea, including members of the genera Mycobacterium, Nostoc, Acinetobacter, Planctomyces, Geobacter, Streptomyces, Methanospirillum, etc. The function is unknown.	7.34227e-44
NC_019678.1|WP_015120988.1|6302888_6303413_-|reverse-transcriptase-like-protein	gnl|CDD|260011	cd09279, RNase_HI_like, RNAse HI family that includes archaeal, some bacterial as well as plant RNase HI. Ribonuclease H (RNase H) is classified into two evolutionarily unrelated families, type 1 (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type 2 (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner. RNase H is involved in DNA replication, repair and transcription. RNase H is widely present in various organisms, including bacteria, archaea and eukaryotes and most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology, type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site (DEDD) residues and have the same catalytic mechanism and functions in cells. One of the important functions of RNase H is to remove Okazaki fragments during DNA replication. Most archaeal genomes contain only type 2 RNase H (RNase HII); however, a few contain RNase HI as well. Although archaeal RNase HI sequences conserve the DEDD active-site motif, they lack other common features important for catalytic function, such as the basic protrusion region. Archaeal RNase HI homologs are more closely related to retroviral RNase HI than bacterial and eukaryotic type I RNase H in enzymatic properties.	5.50745e-20
NC_019678.1|WP_015120985.1|6298294_6300127_+|S8-family-serine-peptidase	gnl|CDD|173810	cd07484, Peptidases_S8_Thermitase_like, Peptidase S8 family domain in Thermitase-like proteins. Thermitase is a non-specific, trypsin-related serine protease with a very high specific activity. It contains a subtilisin like domain. The tertiary structure of thermitase is similar to that of subtilisin BPN'. It contains a Asp/His/Ser catalytic triad. Members of the peptidases S8 (subtilisin and kexin) and S53 (sedolisin) clan include endopeptidases and exopeptidases. The S8 family has an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. Serine acts as a nucleophile, aspartate as an electrophile, and histidine as a base. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of subtilisin. The serine residue here is the nucleophilic equivalent of the serine residue in the S8 family, while glutamic acid has the same role here as the histidine base. However, the aspartic acid residue that acts as an electrophile is quite different. In S53 the it follows glutamic acid, while in S8 it precedes histidine. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. There is a great diversity in the characteristics of their members: some contain disulfide bonds, some are intracellular while others are extracellular, some function at extreme temperatures, and others at high or low pH values.	2.5226e-44
NC_019678.1|WP_015120989.1|6303590_6303830_+|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl|CDD|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	8.61265e-21
NC_019678.1|WP_015120996.1|6312934_6316072_+|HsdR-family-type-I-site-specific-deoxyribonuclease	gnl|CDD|273028	TIGR00348, R_protein, type I site-specific deoxyribonuclease, HsdR family. This gene is part of the type I restriction and modification system which is composed of three polypeptides R (restriction endonuclease), M (modification) and S (specificity). This group of enzymes recognize specific short DNA sequences and have an absolute requirement for ATP (or dATP) and S-adenosyl-L-methionine. They also catalyse the reactions of EC 2.1.1.72 and EC 2.1.1.73, with similar site specificity.(J. Mol. Biol. 271 (3), 342-348 (1997)). Members of this family are assumed to differ from each other in DNA site specificity. [DNA metabolism, Restriction/modification].	6.40122e-116
NC_019678.1|WP_015120995.1|6311648_6312938_+|restriction-endonuclease-S-subunit	gnl|CDD|341150	cd17261, RMtype1_S_EcoKI-TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit TRD-CR, similar to Escherichia coli str. K-12 substr. MG1655 S subunit (S.EcoKI) TRD2-CR2, Escherichia coli A58 S subunit (S.EcoEI) TRD2-CR2, and Aminomonas paucivorans S subunit (S.Apa12260I) TRD2-CR2. Escherichia coli str. K-12 substr. MG1655 S subunit (S.EcoKI) recognizes 5'... AACNNNNNNGTGC ... 3', Escherichia coli A58 S subunit (S.EcoEI) recognizes 5'... GAGNNNNNNNATGC ... 3', and Aminomonas paucivorans S subunit (S.Apa12260I) recognizes 5'... GCCNNNNNCTCC ... 3'. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. For example, S.EcoKI-TRD1 recognizes AAC/GTT and S.EcoKI-TRD2 recognizes GCAC/GTGC, S.EcoEI TRD1 recognizes GAG/CTC and S.EcoEI TRD2 recognizes GCAT/ATGC, and S.Apa12260I TRD1 recognizes GCC/GGC and S.Apa12260I TRD2 recognizes GGAG/CTCC. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	7.5539e-66
NC_019678.1|WP_157229324.1|6300398_6300836_+|protease-complex-subunit-PrcB-family-protein	gnl|CDD|379569	pfam14343, PrcB_C, PrcB C-terminal. This domain is found at the C-terminus of Treponema denticola PrcB. PrcB interacts with the PrtP protease (dentilisin) and is required for the stability of the protease complex.	4.63361e-10
NC_019678.1|WP_015120987.1|6300908_6302408_+|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	gnl|CDD|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	6.01739e-67

Protein sequences

>NC_019678.1|WP_015120992.1|6306037_6306958_-|hypothetical-protein
MTNEFPVLLVTQKAYEASFSETLGSKYKFWFYHKELGSCLYKQSRANLGEDWAEKVAAELCELLGLPHAVYKLASTWEGNRGVVSPNFLPKSGTLVHGNELLSSIVPNYPAFSTYGVSQHTIDVVLSTINRQSVNLPIDWIPPSGIQTAVDVFVGYLLLDAWIGNGDRHHENWGIVRIKAASTSQETAHLAPTYDHASSLGRDLSDEQRQKRSVEAYANKCFSAFYGSVDDKKTLKTFDVFLKVANCYPKAACIWLARLDNITEANILDIFNRVNSSRISSDASNFARSILKINKHRLLSLRKTLS
>NC_019678.1|WP_015120991.1|6305267_6306041_-|HIRAN-domain-containing-protein
MKTKTPTLFLAWQDSISRYWFPIGRLTFDGSVYRFVYTQGVREAKEKFAFKPLSSFPHLDEIYTSTQLFPVFVNRLMSRSRPDYQRFIKWLNIPNDEHDPITILARSGGERETDTLAVFPCPEIDERGQYHLYFFCHGLRHLPSGTIERINQLEFGEKLWLAHEFQNPYDSQALILNTEDHYIVGYCPRYLLAEIFELLRQNSNLEVRVERLNKPPTPLQFRLLCKMSFDIQPGFRPFSNYQYQPINVEVATTIKSS
>NC_019678.1|WP_015120990.1|6304083_6305139_-|hypothetical-protein
MQHEENLLQQCLENLELLPNIQITPKNRPNKRFYSKETGIITIYSPLQSVDYMYAIQPDVTSTTAEVVIDDLLLKQQKVNEKLFLITRSLSEAAINKLVANNIEFIDTNGNIYLNSPAAYIFIREKHLFQEKSVSHSEITSNSLKVIYILLKSPDMLRTSSEELAIAAGVISVTVNDTLNNLYKLGYLQRQRDGKYIITRYTKLLERWEMGYAETLRAELLLGTFTPIVKSKFTVFCASLIQKAKENNFLVGGELGAAIATSYLIPTRAVLYVKENYQLIAEKLKLKPCSEGEIIFCKQFGSYNAYDYNQSEPIIDPLLIYAELIMENNKRLEETAKRIFMKYIKDRQQNA
>NC_019678.1|WP_044291165.1|6303833_6304058_+|type-II-toxin-antitoxin-system-HicA-family-toxin
MFLLLKKTEFIKVIENLGFYLDRQKGSHAIYKDSSGRRVVVPIHAGKYLKQGTLMGMIQDIGIDKETFFELLGK
>NC_019678.1|WP_015120989.1|6303590_6303830_+|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MKNNSKQIYNYTVILEKEADGGYHAFCPVLKGCHSQGDSFEEAIENITEAIELYIESLRADNQSIPKEDLIVKPLSILA
>NC_019678.1|WP_015120988.1|6302888_6303413_-|reverse-transcriptase-like-protein
MAPPKKIIALTPLELNQYQICLFRREGKNKWHIVKILIENAPKSKVEAIEKMKLISEQLKIPWQKKPLKDVTRKRLHNSEKRKARKQARLAARAKRPPILTFDGTSLGRPGISASAAVIEMPDLTYHTTTKFLPRAFADDAEYEGLIIGLEKAKELGISKLEIKGDSQMVIYQI
>NC_019678.1|WP_044291163.1|6302472_6302697_-|reverse-transcriptase-like-protein
MIKPNSKFLDYHEQVLNLLSDFDDYSLCWIPRKQNKLADKAANKCLKEHQPIHTKSLAEEYVEYLIYGNLNEYL
>NC_019678.1|WP_015120987.1|6300908_6302408_+|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit
MQNSHPALSVIKTRQIRQKFVQNEDYLSHELGQAVKKLPPFYTRMLAGGISLLALGTLTWAHFSKVDEVAVAQGKLIPSEQVRPLRSMGEGVIKEIKIKEGDKVNKGDILIERVPDLPEAEINSLENSAKLIEQDLARLAAEHTGKVSTGVGLQDQLLLSRLEDFKNRRAAAVAESNRQLAIKDAAKKRLIGLQLNLVNAKTNLTHAQTSSINAQKLLQQNEKRLKLAHKREQSFASLVSSGAVAHMDYIESQERAISTSADVTRANNEITQARDRITDVRDKITSLLRDIAVQEQEIHQAQQAYTATLNQAKRLDAERTSEILTQTNRRREELTNIQGELAKVKTRRKGETIKAPTQGIAYNLKATVGPVQPGEELLSIVSPKNELVLEAKVLNRDIGFIKEGMDVKVKMSTFPFQEFGTVDGKVIKISPNAVNDEQLGSVFLARIKLTQHSMKVRGKQSNFTPGMTASAEIVTRQKSILMFFIEPIISRFDEAFSAR
>NC_019678.1|WP_157229324.1|6300398_6300836_+|protease-complex-subunit-PrcB-family-protein
MSNLIKFEVVDIGANPLEESFEPDSKVLVFRDKRKWSKFWNTTSTLDLNLQKPEAPKFNFDKQMIIGLTSGSKSTGGYRVIIDKIESIQGKQDKRWIIHYTETIPDDSCILTQKPTTPSIFIVTDKSGISKIDLKGKKMVYSCSN
>NC_019678.1|WP_015120985.1|6298294_6300127_+|S8-family-serine-peptidase
MLLTDKTKNSNGATNSLNTTGNFQILDNSLGSHDLNNYSVSKSRSQSSSSATSKASSAVDPNGSFSKANQLGTLHNSRREYGDIGYHTSYGKDKQDFWKFRLNSNRDVTLSLSGLSEDAGLAIYDSSKKLISWSNKGGNASEFIRSSLSKGDYYALVYKYSGNSTNYTLTTNLNLSKYVSGNLRANTFSLDSRYDKMIFSGNGNVDYGTGQRDILNLSSISSKSVKFNYASIYGGGVLYNPGKGSRVFDAVTLSNGKQILFEGIEKISFRDRTINLSVKPNDPLFKKQWNLHMTGVHNAWRFTKGSSKVLVGIQDTGLGTNSRGFIHSDLRRTTIYKNNYRDEFFRTFKGKGYGRKLTSHGTPVQGIIGAASNNGWGMSGINWNSRVFNVDVLDGNKNDQSLTKATQKMINEASRNGQRLVINMSLSGGSISSAFEKLIARNQKNALFVMSSGNNNRNSLSDPASLSSKYSNVISVGASWGTRDTRGNSRIPGTRISYSGWWGSNYGNGLTLMAPSEVYTTNAKRNPSGIVQFGYDSRFSGTSAAAPHVTGIASLVWSVNSRLSATQIKSILSQTAYNLGARGYDKVYGHGFVNADAAVRRAMALARGAA
>NC_019678.1|WP_015120993.1|6309485_6309932_+|MerR-family-transcriptional-regulator
MEDSFFTSKKAAEITGSTLRQLQYWREKEVVVPTINSSGTGRSVYYSVQDLLKLAVIQYCLKAGLNFDLAATTIKQAESDKLLTPTKYEFDIKQNLNMRYMFSLSEETGKLELGEYDVKKAQSSVETGKPVIPVCLDDIYQQLAEKID
>NC_019678.1|WP_157229458.1|6310104_6311646_+|N-6-DNA-methylase
METWLWEAACKIRGCTDAPKFKDFILPLIFYKRLSDVFDDEFVACEEKFGGTDLARAFIEADHRDALKNNRQPIVRYYIPQDYCWDKIRFHPKDGLGEFVTTAMREVEKLNPGLSETLKLKDYNEKQQNERILDDDRLSSLIEVISRHRLGLKNTNADVLGEAYEYLLRKFAEGQGQSAGEFLTPSEVGWLIGEIIAPEPYTKIYDPTCGSARLLIKPRLVFNRQHPGEESKAPRLYGQELNHTTFSIAKMNMFLQDFTDSQIEIGDTFRQPKFTVDKKLMRFDYVVANPMWNDNNYDADAYEADSFERFKDGIAHKNTADWGWVQIIWASLKDNGRAAVVLDTGAVSRGSGSKNKDKERDIRKEFVEKDRVEGVILLPENLFYNTTAPGVIILLNRQKPLERKGEFLLINAADYFIKGDPKNILTKEGIKKVVEVYQKWETREKFSKIVKLEELNVADYNLSPSQFVDINDKFVHRSIGDILADLAVAKQEREWADKDLNEVLAKLNLDMRG
>NC_019678.1|WP_015120995.1|6311648_6312938_+|restriction-endonuclease-S-subunit
MNEIELPSYWKIINLEKICKKKPQNGAFIKKPEWDEGTIFVNVKDTYRDVVVNLTKVKRLKASLEDVKKYGLKVGDLLFVRSSLKREGIGQCCLIETLIEPAIFDCHLIRISTIKEIAYPLYIAYFFLSEPARNDLIARSKTTTMTTINQQGLIESTIPLPPLPEQKSIAQTLRTIQKAKQTRQRELELERERKAALMQYLFTHGTRNEALQQTEIGEIPESWDVVKLESLLREPLKNGHSAPASNSKEGIRTLILTAVTKNNFSIKNTKLTQANADKVKNLWLEPGDIFIERANTYEMVGLAALYEGETNFAIYPDLMVRVRVKQETIFPKYLVEFFLTPMCRAYFKKNASGTAASMPKIDQGVIRRVNILLPSYEEQKEIVEISRSCDRKISSLEKEIAILDELFHAMLEQLMTGKISTKHLSEIHL
>NC_019678.1|WP_015120996.1|6312934_6316072_+|HsdR-family-type-I-site-specific-deoxyribonuclease
MSEASAVQRPMLKYANQIGWDYLSTKEALQRREGKGEDKLKERYLTDILRTQLIKLNPGVVTSNNVDEILRRLRNLDSTIAGNREALNWLQGKESIFVETENRDRNVTLIDFNNPENNIFQVTDEWTQKGVIVKNRADVIFLINGIPVAIAEAKGERKTDGLALGINQIRRYHNETPEILTFPQLFEVTELWNFWYGLTWNTNRKNLFEWKLTSPLTPPLQGKGNKVIQEGDYEEKIKTFFDKQRFLKVLRYYIVFLERDEGLTKVVLRQHQTRAVEKVIERIQDNTKKKGLVWHTQGSGKTLTMITVAALLRNISGDNTVIMIVDRNELENQLDKNLIAYGIKSYELAENKVELQQLIRDDYRGLIVAMIHKFDKMDVVNQRSTISVLVDEAHRTTGGNFGIYLMAALPNATFIGFTGTPVSKVAKGKKSTFDTFGEPSDDKKTLDLYSTADSVRDGTTLQLNYALAASEFLVPKEILEQEFLQLQNTEDVSDIEELDGILQRAVNLRNFLKSDDRVDKVAQFVAKHFRETVEPMGFKAFLVGVDREACKLYKQALDKYLPAEYSKVVYSRTTEEGLREYNLTETKEKEVRKAFIKKSVVSAQIILSKKAVDFIESRPQDFTYDSNSNLTITGNCSREDVQTLENYCDNEPDAVSKIRQLYEDYSKGLPKILIVTEKLLTGFDAPILYCMYLDKPMRDHVLLQGIARVNRPYADASGLVKPYGFVLDFIGIFGENLEKALSFESGEINHVIQNLDVVKQELNSLMEDTAPVYLPLARGWDDKAKEKAAVHFADKEIREEFFRFARKLQTIYEILSPDPDLGGEFMKKYKAIVRLYATIRAAYNTNPYIDLELVAKTKELVRRNVKIGELEMPGTIHQLNAEQLEKFRQTDTTDNVKILNLSKAISKDVIEGSARSPFLISIGERAEKVRQAFENRQIEASEALTQLNEIADERVEAEQERQQLDVDENTFAIYTVIKQAVDNQNVEQAKTINAVYSNFPDYWWDARQEIDLRTELYATLYPLTNEVEKTIEVSNNLLKLERVES
>NC_019678.1|WP_015120997.1|6316068_6316410_+|M48-family-metallopeptidase
MSATPLQSKIQDSAKWKDSQELKDAVSKWEERINVKVKKISLRGMKRKWASISTTGNLTLNTELLELPKELGEFVIVHELVHLLVPNHGKVFKCFMSIYLPDWEEREKRLQEK
>NC_019678.1|WP_015120998.1|6316575_6317361_+|TIGR04255-family-protein
MKLPDYERVIYEYNPLIEVTAQIRFPTILKITSQQPVDFQDSVRFEYPIFEASRNLQIPVEVSNLLTQFSPNIASDLTYQFKSEDLSWQLSLDKNSITLVTNKYERYEKFIEKFKNTVEIFEKIYNPSFYSRISLRYRDLIIRSKLNIPDKEWMELIPKHIASELYTPELEESIINFVKNLKLQTDFGQVNFNHGLVQVKDTEKNIDELAYLLDADFFTQEKLERGKNVWSTFDKANRTARNLFRWSITEELHNAMRPQTI
>NC_019678.1|WP_015120999.1|6317365_6317761_+|hypothetical-protein
MQTITGSATTNNLIWQRYKLISNPAQTLDWQSLSSGTTNLEVNISIDSPFKAESSEQFVLLVKCLKFISLLFATSPIEGLEEASEALESMVEYYKNNTSDWQQSSLPQSLEIITGNVLPSEVRPPLILDFE
>NC_019678.1|WP_015121000.1|6317769_6318363_+|hypothetical-protein
MPKSLIYRASFFSEALRQGEILTGVRQFKPVPNESLPQIEKIQFKPIIHPYAIIVSQDCDLDWDYAARQNDNKPFKLLNSIIFCEVYTAQDIRSNKENKINSSEWNLVKSNRHMQYHFLEKVPSNCELSQEGLPELTADFKKAFAIDAGFIYHQINHNIAKRRTILECPYLQDFSQRYHAYQGRVALPAQHESEKGG
>NC_019678.1|WP_015121001.1|6318425_6319595_-|hypothetical-protein
MNKIKVSFEHYKFLITEELKSYNSGYFDNAERKAVLLEEFNRQSQLVSRGEAEFHRHQILCANEVFPEAAVANPLADLEVWNLWKSGYRRFPYPGTYRKLNITSQLPKTNSPSSVGVLGEIIAGLFGQAIISPFILVRPIRRFPDFIYSTNNGLYAYLESKAFTTVDSEDGLFSRVKRNELVNFLVESLREMVSDSHVKTWGSFTYIQQINPTKLFTTFIEVDFKERDTYKLELGMMPEPVIQGLAEIAIERGVAKMLDVGMINLINQQNIEKLLMNCAFQEVEALMYEFKLEFASDINYKSINKAITKLLGKVNYSELARVSPENIVSEAQVYLEGRRFEMYDIAKEQRLEVEERWNADWESATEQFYIDNMYGWRFSNKLFWGSIEA
>NC_019678.1|WP_015121002.1|6319704_6320022_-|hypothetical-protein
MNTPSLTQREKDLIRLYCSCKFEMTPQEFYRKWQVSQENIAEICSRSVSTVRYWFCRGRFYRRPLAQDLRHLALMDFLLESFEEIPSKILDKLCLSKNKQSDTTK

Crispr_ID: NC_019678_30

• CRISPR_ID: NC_019678_30
• CRISPR_location: 6326108-6326430
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 4 spacers
• Cas_protein_info: RT

Consensus repeat of NC_019678_30

Consensus_repeat	Method
GTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAAC	CRISPRCasFinder
GTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAAC	CRT
GTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAAC	PILER-CR

spacers of NC_019678_30

>30.1|6326143|37|NC_019678|CRISPRCasFinder,CRT
ACACAGAAAGCAGAAAACATCTTTTCTTAAAGTGGAA
>30.2|6326215|38|NC_019678|CRISPRCasFinder,CRT,PILER-CR
CAGTATTGAATCTGCAAGCTAACACAAATACTAATTTA
>30.3|6326288|36|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AGCTAGTTCTCAAGTTTTAGAAGATTTGGAAGAGTT
>30.4|6326359|37|NC_019678|CRISPRCasFinder,CRT,PILER-CR
GTATGGTCGAAGGAATAGATACAGTAGATCCTCGTGA

CRISPR arrays and Neighbor proteins around NC_019678_30

CRISPR arrays

The CRISPR arrays of NC_019678_30

>merge|NC_019678|30|6326108-6326430|CRISPRCasFinder,CRT,PILER-CR
TCATTCGTCCCCGTGAAGGGGAATTAATTTAAAACACACAGAAAGCAGAAAACATCTTTTCTTAAAGTGGAAGTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAACCAGTATTGAATCTGCAAGCTAACACAAATACTAATTTAGTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAACAGCTAGTTCTCAAGTTTTAGAAGATTTGGAAGAGTTGTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAACGTATGGTCGAAGGAATAGATACAGTAGATCCTCGTGAGTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAAC

>NC_019678|30|27|6326108-6326430|CRISPRCasFinder
TCATTCGTCCCCGTGAAGGGGAATTAATTTAAAAC	ACACAGAAAGCAGAAAACATCTTTTCTTAAAGTGGAA
GTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAAC	CAGTATTGAATCTGCAAGCTAACACAAATACTAATTTA
GTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAAC	AGCTAGTTCTCAAGTTTTAGAAGATTTGGAAGAGTT
GTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAAC	GTATGGTCGAAGGAATAGATACAGTAGATCCTCGTGA
GTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAAC

>NC_019678|30|12|6326108-6326430|CRT
TCATTCGTCCCCGTGAAGGGGAATTAATTTAAAAC	ACACAGAAAGCAGAAAACATCTTTTCTTAAAGTGGAA
GTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAAC	CAGTATTGAATCTGCAAGCTAACACAAATACTAATTTA
GTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAAC	AGCTAGTTCTCAAGTTTTAGAAGATTTGGAAGAGTT
GTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAAC	GTATGGTCGAAGGAATAGATACAGTAGATCCTCGTGA
GTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAAC

>NC_019678|30|13|6326180-6326430|PILER-CR
GTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAAC	CAGTATTGAATCTGCAAGCTAACACAAATACTAATTTA
GTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAAC	AGCTAGTTCTCAAGTTTTAGAAGATTTGGAAGAGTT
GTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAAC	GTATGGTCGAAGGAATAGATACAGTAGATCCTCGTGA
GTTTCCGTCCCCGTGAAGGGGAATTAATTTAAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015120113.1|6326546_6328340_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209
NC_019678.1|WP_157229325.1|6320777_6320954_+|hypothetical-protein	unknown	unknown	gnl|CDD|369567
NC_019678.1|WP_015121003.1|6320033_6320597_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121011.1|6330749_6330965_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121007.1|6322352_6324056_-|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|378147
NC_019678.1|WP_015121009.1|6329970_6330333_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121005.1|6320995_6321514_-|hypothetical-protein	unknown	unknown	gnl|CDD|377670
NC_019678.1|WP_015121018.1|6341350_6341533_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_157229326.1|6339627_6339768_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121002.1|6319704_6320022_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121006.1|6321513_6322350_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|225398
NC_019678.1|WP_015121013.1|6332296_6334582_+|putative-baseplate-assembly-protein	unknown	unknown	gnl|CDD|274051
NC_019678.1|WP_015121012.1|6330984_6332214_-|ISAzo13-like-element-ISRisp1-family-transposase	unknown	unknown	gnl|CDD|369439
NC_019678.1|WP_015121016.1|6336496_6337048_-|DUF4231-domain-containing-protein	unknown	unknown	gnl|CDD|379418
NC_019678.1|WP_015121001.1|6318425_6319595_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121000.1|6317769_6318363_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121008.1|6324328_6325951_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|315987
NC_019678.1|WP_015121014.1|6334854_6335838_+|phage-tail-protein	unknown	unknown	gnl|CDD|274050
NC_019678.1|WP_015121017.1|6340264_6341209_+|nuclease-like-protein	unknown	unknown	gnl|CDD|214615
NC_019678.1|WP_015120999.1|6317365_6317761_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019678.1|WP_015120113.1|6326546_6328340_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	4.7e-50	164.9	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015121006.1|6321513_6322350_-|AAA-family-ATPase	gnl|CDD|225398	COG2842, COG2842, Uncharacterized ATPase, putative transposase [General function prediction only].	1.38186e-57
NC_019678.1|WP_015121012.1|6330984_6332214_-|ISAzo13-like-element-ISRisp1-family-transposase	gnl|CDD|369439	pfam07592, DDE_Tnp_ISAZ013, Rhodopirellula transposase DDE domain. These transposases are found in the planctomycete Rhodopirellula baltica, the cyanobacterium Nostoc, and the Gram-positive bacterium Streptomyces.	0
NC_019678.1|WP_157229325.1|6320777_6320954_+|hypothetical-protein	gnl|CDD|369567	pfam07878, RHH_5, CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5. This family contains bacterial proteins that form a ribbon-helix-helix fold. This fold occurs in many examples of bacterial antitoxins.	0.000264098
NC_019678.1|WP_015121013.1|6332296_6334582_+|putative-baseplate-assembly-protein	gnl|CDD|274051	TIGR02243, hypothetical_protein_SCD8A.17c, putative baseplate assembly protein. This family consists of a large, conserved hypothetical protein in phage tail-like regions of at least six bacterial genomes: Gloeobacter violaceus PCC 7421, Geobacter sulfurreducens PCA, Streptomyces coelicolor A3(2), Streptomyces avermitilis MA-4680, Mesorhizobium loti, and Myxococcus xanthus. The C-terminal region is identified by the broader model pfam04865 as related to baseplate protein J from phage P2, but that relationship is not observed directly. [Mobile and extrachromosomal element functions, Prophage functions].	4.80485e-146
NC_019678.1|WP_015121007.1|6322352_6324056_-|DDE-type-integrase/transposase/recombinase	gnl|CDD|378147	pfam09299, Mu-transpos_C, Mu transposase, C-terminal. Members of this family are found in various prokaryotic integrases and transposases. They adopt a beta-barrel structure with Greek-key topology.	8.99416e-17
NC_019678.1|WP_015121008.1|6324328_6325951_-|tetratricopeptide-repeat-protein	gnl|CDD|315987	pfam13424, TPR_12, Tetratricopeptide repeat.	6.44627e-14
NC_019678.1|WP_015121017.1|6340264_6341209_+|nuclease-like-protein	gnl|CDD|214615	smart00318, SNc, Staphylococcal nuclease homologues.	3.13499e-20
NC_019678.1|WP_015121016.1|6336496_6337048_-|DUF4231-domain-containing-protein	gnl|CDD|379418	pfam14015, DUF4231, Protein of unknown function (DUF4231). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea, eukaryotes and viruses. Proteins in this family are typically between 148 and 288 amino acids in length.	5.01443e-25
NC_019678.1|WP_015121005.1|6320995_6321514_-|hypothetical-protein	gnl|CDD|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	1.18632e-08
NC_019678.1|WP_015120113.1|6326546_6328340_-|group-II-intron-reverse-transcriptase/maturase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	4.85368e-123
NC_019678.1|WP_015121014.1|6334854_6335838_+|phage-tail-protein	gnl|CDD|274050	TIGR02242, putative_secreted_protein, phage tail protein domain. This model describes a region of sequence similarity shared by a number of uncharacterized proteins in bacterial genomes, including Geobacter sulfurreducens PCA, Mesorhizobium loti, Streptomyces coelicolor A3(2), Gloeobacter violaceus PCC 7421, and Myxococcus xanthus. In all cases, the genomic region resembles a phage tail region, based on tentative identifications of neighboring genes. A region of this domain resembles a region of TIGR01634, another phage tail protein model. [Mobile and extrachromosomal element functions, Prophage functions].	5.95875e-33

Protein sequences

>NC_019678.1|WP_015121008.1|6324328_6325951_-|tetratricopeptide-repeat-protein
MNNNTSQNLEEINQLNREVVRLAGEGDIKQAISITKKAIKLTKEKIGEHKVLADSLNNLAELYRIQGNYPDAQPLLIESTEMRKQLLGENHPDVAQSLNNLAAFYVIQGNYPEAENYFFQALHLWKIHLGEEHEEIATILNNIAEVYREQGRYAESEKMHIKSLNMRQSLFGEKHSDVAQSLDNLAAIYENQARYQDAETMHLEALAMRKKLLGEEHWNVAASLNNLAALYNSQGRFAEAEDYYTQACELCKKCLGNDKHPSIAIILNNLGGISENLGRYADAERIHLQALEIRKAIFGKEHLEVAQSLNNLGNVYLLRGLYLKAEEVYQQAYDIRKLFLNPEHPDIVQLLHNFAVLYTYQGRYQTAESICLKTLDSIEKAYGKNHPNYADNLNHLALVYQKQGNYSQAEQKYLTVLAIRKNIFGEEHHDIVKSLNRIAEIYRLQGRYSQAEAIYKENYQLAKRLLGEMHPDVAGILNSLAVLYDAQFKYAEAEKLFTEVLLIIRSQFGNNHPQVATTLNNLATVYGSLERFSEAEEFVH
>NC_019678.1|WP_015121007.1|6322352_6324056_-|DDE-type-integrase/transposase/recombinase
MHDSEFSATSKGLSCAASQKEENVIVSELSDEARLKIEVIQSLLQNDDGATYTQRLQQAAKKLGKSVRTVRRLVDKWEREGLAGLVQNRRADKGKYRVDQNWQEFVLKTYKEGNKGSRRMTRQQVFIRVKARANELNLKPPSHMTVYRILQPLIDKQEQVKSVRSPGWRGSRLSVKTRDGNDLQVEYSNQVWQCDHTLADILLVDRHGKVLGRPWLTTVIDSYSRCIMGINLGYDAPSSQVVALALRHAILAKQYGSEYGLHEKWGTYGLPQHFYTDGGRDFRSNHLQEIGVQLGFVCHLRDRPSEGGSVERPFKTFNTELFSTLQGYTGSNVQERPKEAEKDACLTLRQLEQLLVRYIVDNYNQRLDARMGDQTRFQRWESGLIGMPNLLSDRDLDICLMKKMRRQIQRGGYLQFENLMYRGELLAGYAGESVVLRYDPRDITTVLVYRRKGSKEEFLARAFAQDLETEQVSLDEAKASSRKVREAGKEVSNRSIFAEVRDRETFTTTKKTKKQRQKAEQAELKQAQQPLPVEVSEEVEVTKNESQPEVEMLEVFDYEQMQEDYGF
>NC_019678.1|WP_015121006.1|6321513_6322350_-|AAA-family-ATPase
MTDIQAQAVAQQLGAIPTNNENLQAEIQRLRGKNFVPLEQVKKLHDWLEGKRQSRQSGRVVGESRTGKTMGCNAYRLRHKPTQKHGKPPTVPVVYIQIPQECGARDLFSMILEHLKYQVTKGTVSEIRDRAFRVLKGCAVEMVIIDEADRLKPKTFAEVRDIFDKLEIPVILVGTDRLDTVIKRDEQVYNRFRSCHRFGKFSGEDFKRTVEIWEKQILKLPVASNLSSKKILKTLGEATGGYIGLMDMILRESAIRALKKGLQKIDLETLKEVTEEYR
>NC_019678.1|WP_015121005.1|6320995_6321514_-|hypothetical-protein
MQAENIKPWLFRVKPLEGESLSHFLGRFRRANDLTPSGLGKATGLGGAIARWEKFRFIPSPSHQQLGKLASVVGVDVDRLVMMLPPAGVGMKLEPIRLCGACYAESPRHKIKWQFKVTQGCNQHKSTLLSECPECGARFKVPALWVDGWCHRCFTTFGEMSKYQKSITVFNS
>NC_019678.1|WP_157229325.1|6320777_6320954_+|hypothetical-protein
MAKVTVTLYMEEEDKEALQELADVEERSLSQMAVLILKRAIKQARTEGKISSDGGKEK
>NC_019678.1|WP_015121003.1|6320033_6320597_-|hypothetical-protein
MLKQVSHKTDWYRGYQQALEDFNITQLLAKVRNDLEANLISVAFSNSDSEASSHVQQEDVDSLAAILIAQFTSKINSELIPKYLLAIRLGNLQIKSNIINQKFLHQSPDLPKNFPDEAKIPCFLYGDKLRWVNSDSEWGTVIGRFYAFAPHLCEWTWCYLIWISNDSPSASWTPTDIAWEDDLEAFT
>NC_019678.1|WP_015121002.1|6319704_6320022_-|hypothetical-protein
MNTPSLTQREKDLIRLYCSCKFEMTPQEFYRKWQVSQENIAEICSRSVSTVRYWFCRGRFYRRPLAQDLRHLALMDFLLESFEEIPSKILDKLCLSKNKQSDTTK
>NC_019678.1|WP_015121001.1|6318425_6319595_-|hypothetical-protein
MNKIKVSFEHYKFLITEELKSYNSGYFDNAERKAVLLEEFNRQSQLVSRGEAEFHRHQILCANEVFPEAAVANPLADLEVWNLWKSGYRRFPYPGTYRKLNITSQLPKTNSPSSVGVLGEIIAGLFGQAIISPFILVRPIRRFPDFIYSTNNGLYAYLESKAFTTVDSEDGLFSRVKRNELVNFLVESLREMVSDSHVKTWGSFTYIQQINPTKLFTTFIEVDFKERDTYKLELGMMPEPVIQGLAEIAIERGVAKMLDVGMINLINQQNIEKLLMNCAFQEVEALMYEFKLEFASDINYKSINKAITKLLGKVNYSELARVSPENIVSEAQVYLEGRRFEMYDIAKEQRLEVEERWNADWESATEQFYIDNMYGWRFSNKLFWGSIEA
>NC_019678.1|WP_015121000.1|6317769_6318363_+|hypothetical-protein
MPKSLIYRASFFSEALRQGEILTGVRQFKPVPNESLPQIEKIQFKPIIHPYAIIVSQDCDLDWDYAARQNDNKPFKLLNSIIFCEVYTAQDIRSNKENKINSSEWNLVKSNRHMQYHFLEKVPSNCELSQEGLPELTADFKKAFAIDAGFIYHQINHNIAKRRTILECPYLQDFSQRYHAYQGRVALPAQHESEKGG
>NC_019678.1|WP_015120999.1|6317365_6317761_+|hypothetical-protein
MQTITGSATTNNLIWQRYKLISNPAQTLDWQSLSSGTTNLEVNISIDSPFKAESSEQFVLLVKCLKFISLLFATSPIEGLEEASEALESMVEYYKNNTSDWQQSSLPQSLEIITGNVLPSEVRPPLILDFE
>NC_019678.1|WP_015120113.1|6326546_6328340_-|group-II-intron-reverse-transcriptase/maturase
MVQSTIVNVTERATDWNSIKWKHANRVVTRLRQRIFKATRDGDLKKIRSLQKLLMRSYSNIVLSVRRVTQLNSGKKTAGVDKLLVLTPGARGTLVDILTRCPPWKPLPVKRVYIRKSNGKQRPLGIPCVIDRCLQAIVKNALEPYWEAQFERTSYGFRPGRGVHDAIERIHSMSKANSTKSWVVDADIEGCFDNIAHSPLLKTIGNFPAKKLIQQWLKAGYVDKGVFNDTETGVPQGGIISPLLANIALHGMESALGIRYDKHGHTIGNRGIVRYADDLVVFCKTQEDAACVVETLSHWMKSKGLALSKAKTNIVHLSEGFNFLSFNIRWYKDKNTKIGRKVLIKPSKEALQDVRNKIKQVWLENKSSNVNYLISKLNPIIRGVANYYRTVVSSHIFHKLDTWMYVRENRYAKRVHPKKSSGWRKHKYWGRLNFDRNDNWVFGEPVAVDGFPGISKLVNPEGDKRTGQYLLKFSWFNIRRHTLVKGDASYDNPDLVKYWESRTKRKSQNLIPSYQKLARKQGYKCCVCGESLFNDEPIQKHHKVPQSRGGKDTYANLELMHYYCHRQVHSVAPGCEDEVFVQDLQELNPVPGSVRIG
>NC_019678.1|WP_015121009.1|6329970_6330333_+|hypothetical-protein
MKTPQEIASELNQFYGSTTLYKHWLGLKYTEGVQYLAQETNCYWLLDAIASHQTKKFLSNPKLREFQIWHLRVQENSGVLICEWDTNQEVLRQEIEYTDFPLSHIKLYLVEKVLMLPNEY
>NC_019678.1|WP_015121011.1|6330749_6330965_-|hypothetical-protein
MNPYGLIGGFYAVISFIGLLDLGLSATGISEVKRLVPELYAQGITPSVKNLASVMTNPEALWREEVLETPP
>NC_019678.1|WP_015121012.1|6330984_6332214_-|ISAzo13-like-element-ISRisp1-family-transposase
MPDNHKVKIIQDKYDSLSPYLNEKTRRIWAAIEAQSLGWGGVTAVAIATGLSRTTIHSGIDLLSKLDEVKTEDESTRIRTVGGGRKLLEEKDAMLLSDLESLLEPMTLGDPESPIKWTNKSVVKLAAALKEGGHSISPKSVYNLLESLGYSLQSNRKTRDGSSHEDRDDQFLYISNQVKYFQSHNEPVISVDTKKKELIGNFKNPGTEWCDSEQPVEVRMHDFVDPNAGKAIPYGIYDLTLNKGWVNVGIDHDTAEFAVESIRHWWYSMGNLLYPKSEHIMITADSGGSNSYRSRLWKLKLQEFATEIGKSIHVCHFPPGTSKWNKIEHRLFCHITTNWRGRPLTSLQVVINLIGNTTTTQGLVVEARLDENLYQTGIKVTDKELDNIAIERNSFHGEWNYIIKPQISG
>NC_019678.1|WP_015121013.1|6332296_6334582_+|putative-baseplate-assembly-protein
MDFEFLPKLPKSNLDDRTFKDLVEECILRIPRYCPEWTNHNPSDPGITLIELFAWLTDQMLLRFNQVPRRNYVAFLELMGIRLNPPSPATCKLTFYLSAAQTQEVPIPRFTEVATVRTETEEAVIFTTDKELFIGNPQINYLLAANKATDKAETISKEDLRSLTPDNRRWQDLGETLLFDLDQPSPGNCFYLVFSESENSIAGNAIAITFTGEPGRTTGIDPNNPPLRWQAWDGQNWVNVLREKNDDKTKGFSFKGIAQPLEGADVILHLPLDLPVFNVIDTSYRGHWIRCTYIDPQESQQHYSSSPSIVGLTVRSIGGAVKATQCIRVEQELLGVSNGKAGQTFELQSKPVLKREPSFGEHIRIKLPGERSENPLDWEQWQEVSDFAVSGPEDPHYTIDSQTGEIQFGPLIREPSQLRQQIYQRGKVQPVGRIVRRDDHKADNLATYTPPSVSNTAGEIALERQYGKVPPPGSEIYMMAYRTGGGTTGNVKDSKITVIKNSIPYVKSVINYEDAYGGTDPESLDEAAIRVPELLRTRECGVTPEDFERIARTASKLVARAHCLTKPEHTTAGIVRLLIVPQFKNLDHFDFRRGMNPDAEFALSRELKEEIKNYMSDRKPLGVDINLEEPEYTGVSVRAEIILEPQYNNPGDKEKIRDNLLVAIYRFLNPLVGGFEEKGWDLGRSVYSSDIVAVCQKIPGVRYLGRVELFRCSKFESELNSKWLREDFSESEIEPGSLGLICSWQDNNQQLNSGHIIEFRE
>NC_019678.1|WP_015121014.1|6334854_6335838_+|phage-tail-protein
MVLAVQITPMQPLQADISSEKSKEPVSNNLPLYPGEAGEFLVTLSNPTDSSLEWKLEIEGDFPSDWCNRNQTSFEEILPRGKREFPIYLIVPDNFFEDSHTINKNQPRLQIDYQMQISIYTTQTGNEPQLIKYQVLNLLVRPNISYLDFLPNIYQEVDFVGRLVGIFEQAFDPVVQTIDTLWAYLDPLTAPTALQNFLAHWVAWDIDSRWDIDKQRQLIRNAITIYRWHGTRYGLRLYLHLYTGLPLDEDSPEVDKHISIQEVFNNGFVLGKTFIGQDSMIGGGRPYHFIVRLRATESLHIDESLVRKIIEQQKPAFSTYELSIINP
>NC_019678.1|WP_015121016.1|6336496_6337048_-|DUF4231-domain-containing-protein
MNSQKKIIDNPIVPAREKALGYAQELIKDYKKTRAISRNLYYGLQIGTIILSGVTPILVLVDKIQASDTWLKWLPVIFPAVASIVASIVTSFPFQENWISANTTVELLEAEQEKFVLGITPLYRCYDSINENEQEKRAKKSIENFITQVNNIHLNQVQQTSSFVSNEDMAEQKEKDKTAQAVT
>NC_019678.1|WP_157229326.1|6339627_6339768_+|hypothetical-protein
MLKEELADAEIGSAELDVLQFGGLEDGYINAVEDIGASEEAGEEED
>NC_019678.1|WP_015121017.1|6340264_6341209_+|nuclease-like-protein
MRATKEKAKAIKGTTVDATVVRVVDGDTVRVEVQGKEESLRILGLDTEESNAGSPKPVSPWGKEAKKEAEKLFKAGDKVKLEFPGDEVVEECMQKYRGNYGRLLVFVYLDDGTDFQEYMIQKGFSPYFMKYGYAALLDNHERYMQAEKEAQIANRGVWNQIEVNGSEVRNYAALGVWWYLRAEIIQNYRQFKQENEDATVFNTRLDYEKVLELAKKEEEATIFTELRNPKRVASNSMLIGIGSVEKPFSIFIPKVDEAAGEKIMSLITNRYISTDEEHPRRSYAYVKGKLSIYRDKPQVIVTNVKQVMDLPQLD
>NC_019678.1|WP_015121018.1|6341350_6341533_-|hypothetical-protein
MFPFWMNSCCGTDSFSTTRHQENKLKFLKFMRDNVEARLAALNAAIETIENQLSRNTDSV

Crispr_ID: NC_019678_31

• CRISPR_ID: NC_019678_31
• CRISPR_location: 6328927-6329393
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 6 spacers
• Cas_protein_info: RT

Consensus repeat of NC_019678_31

Consensus_repeat	Method
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	CRISPRCasFinder
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	CRT
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	PILER-CR

spacers of NC_019678_31

>31.1|6328962|36|NC_019678|CRISPRCasFinder,CRT
TTCGTAGAGCTCAATACCAGATCGTGAACCAAGGAG
>31.2|6329033|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AAGTTAGAGATTACTTACTTTTTGATCGTATTGGC
>31.3|6329103|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR
TGAAAACCGCATTGTCGCCAATTGCCGCATTGAAA
>31.4|6329173|38|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AATTGCAGCATGCAAATAGTGTAGAAGATGTGGGAAAA
>31.5|6329246|37|NC_019678|CRISPRCasFinder,CRT,PILER-CR
CATATTTCTACAAAATCCACATCTGTGGTAGGTGATA
>31.6|6329318|41|NC_019678|CRISPRCasFinder,CRT,PILER-CR
AATAAGCGGAAAATTTTTGGTCCTGCTGAAACTCTTAAAGT

CRISPR arrays and Neighbor proteins around NC_019678_31

CRISPR arrays

The CRISPR arrays of NC_019678_31

>merge|NC_019678|31|6328927-6329393|CRISPRCasFinder,CRT,PILER-CR
GCACCCATCCCCGTAAGGGGTTAAGGAATTAAAACTTCGTAGAGCTCAATACCAGATCGTGAACCAAGGAGGTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAACAAGTTAGAGATTACTTACTTTTTGATCGTATTGGCGTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAACTGAAAACCGCATTGTCGCCAATTGCCGCATTGAAAGTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAACAATTGCAGCATGCAAATAGTGTAGAAGATGTGGGAAAAGTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAACCATATTTCTACAAAATCCACATCTGTGGTAGGTGATAGTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAACAATAAGCGGAAAATTTTTGGTCCTGCTGAAACTCTTAAAGTGTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC

>NC_019678|31|28|6328927-6329393|CRISPRCasFinder
GCACCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	TTCGTAGAGCTCAATACCAGATCGTGAACCAAGGAG
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	AAGTTAGAGATTACTTACTTTTTGATCGTATTGGC
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	TGAAAACCGCATTGTCGCCAATTGCCGCATTGAAA
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	AATTGCAGCATGCAAATAGTGTAGAAGATGTGGGAAAA
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	CATATTTCTACAAAATCCACATCTGTGGTAGGTGATA
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	AATAAGCGGAAAATTTTTGGTCCTGCTGAAACTCTTAAAGT
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC

>NC_019678|31|13|6328927-6329393|CRT
GCACCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	TTCGTAGAGCTCAATACCAGATCGTGAACCAAGGAG
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	AAGTTAGAGATTACTTACTTTTTGATCGTATTGGC
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	TGAAAACCGCATTGTCGCCAATTGCCGCATTGAAA
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	AATTGCAGCATGCAAATAGTGTAGAAGATGTGGGAAAA
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	CATATTTCTACAAAATCCACATCTGTGGTAGGTGATA
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	AATAAGCGGAAAATTTTTGGTCCTGCTGAAACTCTTAAAGT
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC

>NC_019678|31|14|6328998-6329393|PILER-CR
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	AAGTTAGAGATTACTTACTTTTTGATCGTATTGGC
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	TGAAAACCGCATTGTCGCCAATTGCCGCATTGAAA
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	AATTGCAGCATGCAAATAGTGTAGAAGATGTGGGAAAA
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	CATATTTCTACAAAATCCACATCTGTGGTAGGTGATA
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC	AATAAGCGGAAAATTTTTGGTCCTGCTGAAACTCTTAAAGT
GTTTCCATCCCCGTAAGGGGTTAAGGAATTAAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015120113.1|6326546_6328340_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209
NC_019678.1|WP_157229325.1|6320777_6320954_+|hypothetical-protein	unknown	unknown	gnl|CDD|369567
NC_019678.1|WP_015121003.1|6320033_6320597_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121011.1|6330749_6330965_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121007.1|6322352_6324056_-|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|378147
NC_019678.1|WP_015121009.1|6329970_6330333_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121005.1|6320995_6321514_-|hypothetical-protein	unknown	unknown	gnl|CDD|377670
NC_019678.1|WP_015121018.1|6341350_6341533_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121002.1|6319704_6320022_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121006.1|6321513_6322350_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|225398
NC_019678.1|WP_015121013.1|6332296_6334582_+|putative-baseplate-assembly-protein	unknown	unknown	gnl|CDD|274051
NC_019678.1|WP_015121012.1|6330984_6332214_-|ISAzo13-like-element-ISRisp1-family-transposase	unknown	unknown	gnl|CDD|369439
NC_019678.1|WP_015121016.1|6336496_6337048_-|DUF4231-domain-containing-protein	unknown	unknown	gnl|CDD|379418
NC_019678.1|WP_015121001.1|6318425_6319595_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121000.1|6317769_6318363_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121008.1|6324328_6325951_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|315987
NC_019678.1|WP_157229326.1|6339627_6339768_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121019.1|6341684_6343514_-|glycoside-hydrolase-family-15-protein	unknown	unknown	gnl|CDD|225922
NC_019678.1|WP_015121017.1|6340264_6341209_+|nuclease-like-protein	unknown	unknown	gnl|CDD|214615
NC_019678.1|WP_015121014.1|6334854_6335838_+|phage-tail-protein	unknown	unknown	gnl|CDD|274050

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019678.1|WP_015120113.1|6326546_6328340_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	4.7e-50	164.9	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015120113.1|6326546_6328340_-|group-II-intron-reverse-transcriptase/maturase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	4.85368e-123
NC_019678.1|WP_157229325.1|6320777_6320954_+|hypothetical-protein	gnl|CDD|369567	pfam07878, RHH_5, CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5. This family contains bacterial proteins that form a ribbon-helix-helix fold. This fold occurs in many examples of bacterial antitoxins.	0.000264098
NC_019678.1|WP_015121013.1|6332296_6334582_+|putative-baseplate-assembly-protein	gnl|CDD|274051	TIGR02243, hypothetical_protein_SCD8A.17c, putative baseplate assembly protein. This family consists of a large, conserved hypothetical protein in phage tail-like regions of at least six bacterial genomes: Gloeobacter violaceus PCC 7421, Geobacter sulfurreducens PCA, Streptomyces coelicolor A3(2), Streptomyces avermitilis MA-4680, Mesorhizobium loti, and Myxococcus xanthus. The C-terminal region is identified by the broader model pfam04865 as related to baseplate protein J from phage P2, but that relationship is not observed directly. [Mobile and extrachromosomal element functions, Prophage functions].	4.80485e-146
NC_019678.1|WP_015121017.1|6340264_6341209_+|nuclease-like-protein	gnl|CDD|214615	smart00318, SNc, Staphylococcal nuclease homologues.	3.13499e-20
NC_019678.1|WP_015121005.1|6320995_6321514_-|hypothetical-protein	gnl|CDD|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	1.18632e-08
NC_019678.1|WP_015121006.1|6321513_6322350_-|AAA-family-ATPase	gnl|CDD|225398	COG2842, COG2842, Uncharacterized ATPase, putative transposase [General function prediction only].	1.38186e-57
NC_019678.1|WP_015121019.1|6341684_6343514_-|glycoside-hydrolase-family-15-protein	gnl|CDD|225922	COG3387, SGA1, Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism].	2.80046e-126
NC_019678.1|WP_015121012.1|6330984_6332214_-|ISAzo13-like-element-ISRisp1-family-transposase	gnl|CDD|369439	pfam07592, DDE_Tnp_ISAZ013, Rhodopirellula transposase DDE domain. These transposases are found in the planctomycete Rhodopirellula baltica, the cyanobacterium Nostoc, and the Gram-positive bacterium Streptomyces.	0
NC_019678.1|WP_015121016.1|6336496_6337048_-|DUF4231-domain-containing-protein	gnl|CDD|379418	pfam14015, DUF4231, Protein of unknown function (DUF4231). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea, eukaryotes and viruses. Proteins in this family are typically between 148 and 288 amino acids in length.	5.01443e-25
NC_019678.1|WP_015121007.1|6322352_6324056_-|DDE-type-integrase/transposase/recombinase	gnl|CDD|378147	pfam09299, Mu-transpos_C, Mu transposase, C-terminal. Members of this family are found in various prokaryotic integrases and transposases. They adopt a beta-barrel structure with Greek-key topology.	8.99416e-17
NC_019678.1|WP_015121008.1|6324328_6325951_-|tetratricopeptide-repeat-protein	gnl|CDD|315987	pfam13424, TPR_12, Tetratricopeptide repeat.	6.44627e-14
NC_019678.1|WP_015121014.1|6334854_6335838_+|phage-tail-protein	gnl|CDD|274050	TIGR02242, putative_secreted_protein, phage tail protein domain. This model describes a region of sequence similarity shared by a number of uncharacterized proteins in bacterial genomes, including Geobacter sulfurreducens PCA, Mesorhizobium loti, Streptomyces coelicolor A3(2), Gloeobacter violaceus PCC 7421, and Myxococcus xanthus. In all cases, the genomic region resembles a phage tail region, based on tentative identifications of neighboring genes. A region of this domain resembles a region of TIGR01634, another phage tail protein model. [Mobile and extrachromosomal element functions, Prophage functions].	5.95875e-33

Protein sequences

>NC_019678.1|WP_015120113.1|6326546_6328340_-|group-II-intron-reverse-transcriptase/maturase
MVQSTIVNVTERATDWNSIKWKHANRVVTRLRQRIFKATRDGDLKKIRSLQKLLMRSYSNIVLSVRRVTQLNSGKKTAGVDKLLVLTPGARGTLVDILTRCPPWKPLPVKRVYIRKSNGKQRPLGIPCVIDRCLQAIVKNALEPYWEAQFERTSYGFRPGRGVHDAIERIHSMSKANSTKSWVVDADIEGCFDNIAHSPLLKTIGNFPAKKLIQQWLKAGYVDKGVFNDTETGVPQGGIISPLLANIALHGMESALGIRYDKHGHTIGNRGIVRYADDLVVFCKTQEDAACVVETLSHWMKSKGLALSKAKTNIVHLSEGFNFLSFNIRWYKDKNTKIGRKVLIKPSKEALQDVRNKIKQVWLENKSSNVNYLISKLNPIIRGVANYYRTVVSSHIFHKLDTWMYVRENRYAKRVHPKKSSGWRKHKYWGRLNFDRNDNWVFGEPVAVDGFPGISKLVNPEGDKRTGQYLLKFSWFNIRRHTLVKGDASYDNPDLVKYWESRTKRKSQNLIPSYQKLARKQGYKCCVCGESLFNDEPIQKHHKVPQSRGGKDTYANLELMHYYCHRQVHSVAPGCEDEVFVQDLQELNPVPGSVRIG
>NC_019678.1|WP_015121008.1|6324328_6325951_-|tetratricopeptide-repeat-protein
MNNNTSQNLEEINQLNREVVRLAGEGDIKQAISITKKAIKLTKEKIGEHKVLADSLNNLAELYRIQGNYPDAQPLLIESTEMRKQLLGENHPDVAQSLNNLAAFYVIQGNYPEAENYFFQALHLWKIHLGEEHEEIATILNNIAEVYREQGRYAESEKMHIKSLNMRQSLFGEKHSDVAQSLDNLAAIYENQARYQDAETMHLEALAMRKKLLGEEHWNVAASLNNLAALYNSQGRFAEAEDYYTQACELCKKCLGNDKHPSIAIILNNLGGISENLGRYADAERIHLQALEIRKAIFGKEHLEVAQSLNNLGNVYLLRGLYLKAEEVYQQAYDIRKLFLNPEHPDIVQLLHNFAVLYTYQGRYQTAESICLKTLDSIEKAYGKNHPNYADNLNHLALVYQKQGNYSQAEQKYLTVLAIRKNIFGEEHHDIVKSLNRIAEIYRLQGRYSQAEAIYKENYQLAKRLLGEMHPDVAGILNSLAVLYDAQFKYAEAEKLFTEVLLIIRSQFGNNHPQVATTLNNLATVYGSLERFSEAEEFVH
>NC_019678.1|WP_015121007.1|6322352_6324056_-|DDE-type-integrase/transposase/recombinase
MHDSEFSATSKGLSCAASQKEENVIVSELSDEARLKIEVIQSLLQNDDGATYTQRLQQAAKKLGKSVRTVRRLVDKWEREGLAGLVQNRRADKGKYRVDQNWQEFVLKTYKEGNKGSRRMTRQQVFIRVKARANELNLKPPSHMTVYRILQPLIDKQEQVKSVRSPGWRGSRLSVKTRDGNDLQVEYSNQVWQCDHTLADILLVDRHGKVLGRPWLTTVIDSYSRCIMGINLGYDAPSSQVVALALRHAILAKQYGSEYGLHEKWGTYGLPQHFYTDGGRDFRSNHLQEIGVQLGFVCHLRDRPSEGGSVERPFKTFNTELFSTLQGYTGSNVQERPKEAEKDACLTLRQLEQLLVRYIVDNYNQRLDARMGDQTRFQRWESGLIGMPNLLSDRDLDICLMKKMRRQIQRGGYLQFENLMYRGELLAGYAGESVVLRYDPRDITTVLVYRRKGSKEEFLARAFAQDLETEQVSLDEAKASSRKVREAGKEVSNRSIFAEVRDRETFTTTKKTKKQRQKAEQAELKQAQQPLPVEVSEEVEVTKNESQPEVEMLEVFDYEQMQEDYGF
>NC_019678.1|WP_015121006.1|6321513_6322350_-|AAA-family-ATPase
MTDIQAQAVAQQLGAIPTNNENLQAEIQRLRGKNFVPLEQVKKLHDWLEGKRQSRQSGRVVGESRTGKTMGCNAYRLRHKPTQKHGKPPTVPVVYIQIPQECGARDLFSMILEHLKYQVTKGTVSEIRDRAFRVLKGCAVEMVIIDEADRLKPKTFAEVRDIFDKLEIPVILVGTDRLDTVIKRDEQVYNRFRSCHRFGKFSGEDFKRTVEIWEKQILKLPVASNLSSKKILKTLGEATGGYIGLMDMILRESAIRALKKGLQKIDLETLKEVTEEYR
>NC_019678.1|WP_015121005.1|6320995_6321514_-|hypothetical-protein
MQAENIKPWLFRVKPLEGESLSHFLGRFRRANDLTPSGLGKATGLGGAIARWEKFRFIPSPSHQQLGKLASVVGVDVDRLVMMLPPAGVGMKLEPIRLCGACYAESPRHKIKWQFKVTQGCNQHKSTLLSECPECGARFKVPALWVDGWCHRCFTTFGEMSKYQKSITVFNS
>NC_019678.1|WP_157229325.1|6320777_6320954_+|hypothetical-protein
MAKVTVTLYMEEEDKEALQELADVEERSLSQMAVLILKRAIKQARTEGKISSDGGKEK
>NC_019678.1|WP_015121003.1|6320033_6320597_-|hypothetical-protein
MLKQVSHKTDWYRGYQQALEDFNITQLLAKVRNDLEANLISVAFSNSDSEASSHVQQEDVDSLAAILIAQFTSKINSELIPKYLLAIRLGNLQIKSNIINQKFLHQSPDLPKNFPDEAKIPCFLYGDKLRWVNSDSEWGTVIGRFYAFAPHLCEWTWCYLIWISNDSPSASWTPTDIAWEDDLEAFT
>NC_019678.1|WP_015121002.1|6319704_6320022_-|hypothetical-protein
MNTPSLTQREKDLIRLYCSCKFEMTPQEFYRKWQVSQENIAEICSRSVSTVRYWFCRGRFYRRPLAQDLRHLALMDFLLESFEEIPSKILDKLCLSKNKQSDTTK
>NC_019678.1|WP_015121001.1|6318425_6319595_-|hypothetical-protein
MNKIKVSFEHYKFLITEELKSYNSGYFDNAERKAVLLEEFNRQSQLVSRGEAEFHRHQILCANEVFPEAAVANPLADLEVWNLWKSGYRRFPYPGTYRKLNITSQLPKTNSPSSVGVLGEIIAGLFGQAIISPFILVRPIRRFPDFIYSTNNGLYAYLESKAFTTVDSEDGLFSRVKRNELVNFLVESLREMVSDSHVKTWGSFTYIQQINPTKLFTTFIEVDFKERDTYKLELGMMPEPVIQGLAEIAIERGVAKMLDVGMINLINQQNIEKLLMNCAFQEVEALMYEFKLEFASDINYKSINKAITKLLGKVNYSELARVSPENIVSEAQVYLEGRRFEMYDIAKEQRLEVEERWNADWESATEQFYIDNMYGWRFSNKLFWGSIEA
>NC_019678.1|WP_015121000.1|6317769_6318363_+|hypothetical-protein
MPKSLIYRASFFSEALRQGEILTGVRQFKPVPNESLPQIEKIQFKPIIHPYAIIVSQDCDLDWDYAARQNDNKPFKLLNSIIFCEVYTAQDIRSNKENKINSSEWNLVKSNRHMQYHFLEKVPSNCELSQEGLPELTADFKKAFAIDAGFIYHQINHNIAKRRTILECPYLQDFSQRYHAYQGRVALPAQHESEKGG
>NC_019678.1|WP_015121009.1|6329970_6330333_+|hypothetical-protein
MKTPQEIASELNQFYGSTTLYKHWLGLKYTEGVQYLAQETNCYWLLDAIASHQTKKFLSNPKLREFQIWHLRVQENSGVLICEWDTNQEVLRQEIEYTDFPLSHIKLYLVEKVLMLPNEY
>NC_019678.1|WP_015121011.1|6330749_6330965_-|hypothetical-protein
MNPYGLIGGFYAVISFIGLLDLGLSATGISEVKRLVPELYAQGITPSVKNLASVMTNPEALWREEVLETPP
>NC_019678.1|WP_015121012.1|6330984_6332214_-|ISAzo13-like-element-ISRisp1-family-transposase
MPDNHKVKIIQDKYDSLSPYLNEKTRRIWAAIEAQSLGWGGVTAVAIATGLSRTTIHSGIDLLSKLDEVKTEDESTRIRTVGGGRKLLEEKDAMLLSDLESLLEPMTLGDPESPIKWTNKSVVKLAAALKEGGHSISPKSVYNLLESLGYSLQSNRKTRDGSSHEDRDDQFLYISNQVKYFQSHNEPVISVDTKKKELIGNFKNPGTEWCDSEQPVEVRMHDFVDPNAGKAIPYGIYDLTLNKGWVNVGIDHDTAEFAVESIRHWWYSMGNLLYPKSEHIMITADSGGSNSYRSRLWKLKLQEFATEIGKSIHVCHFPPGTSKWNKIEHRLFCHITTNWRGRPLTSLQVVINLIGNTTTTQGLVVEARLDENLYQTGIKVTDKELDNIAIERNSFHGEWNYIIKPQISG
>NC_019678.1|WP_015121013.1|6332296_6334582_+|putative-baseplate-assembly-protein
MDFEFLPKLPKSNLDDRTFKDLVEECILRIPRYCPEWTNHNPSDPGITLIELFAWLTDQMLLRFNQVPRRNYVAFLELMGIRLNPPSPATCKLTFYLSAAQTQEVPIPRFTEVATVRTETEEAVIFTTDKELFIGNPQINYLLAANKATDKAETISKEDLRSLTPDNRRWQDLGETLLFDLDQPSPGNCFYLVFSESENSIAGNAIAITFTGEPGRTTGIDPNNPPLRWQAWDGQNWVNVLREKNDDKTKGFSFKGIAQPLEGADVILHLPLDLPVFNVIDTSYRGHWIRCTYIDPQESQQHYSSSPSIVGLTVRSIGGAVKATQCIRVEQELLGVSNGKAGQTFELQSKPVLKREPSFGEHIRIKLPGERSENPLDWEQWQEVSDFAVSGPEDPHYTIDSQTGEIQFGPLIREPSQLRQQIYQRGKVQPVGRIVRRDDHKADNLATYTPPSVSNTAGEIALERQYGKVPPPGSEIYMMAYRTGGGTTGNVKDSKITVIKNSIPYVKSVINYEDAYGGTDPESLDEAAIRVPELLRTRECGVTPEDFERIARTASKLVARAHCLTKPEHTTAGIVRLLIVPQFKNLDHFDFRRGMNPDAEFALSRELKEEIKNYMSDRKPLGVDINLEEPEYTGVSVRAEIILEPQYNNPGDKEKIRDNLLVAIYRFLNPLVGGFEEKGWDLGRSVYSSDIVAVCQKIPGVRYLGRVELFRCSKFESELNSKWLREDFSESEIEPGSLGLICSWQDNNQQLNSGHIIEFRE
>NC_019678.1|WP_015121014.1|6334854_6335838_+|phage-tail-protein
MVLAVQITPMQPLQADISSEKSKEPVSNNLPLYPGEAGEFLVTLSNPTDSSLEWKLEIEGDFPSDWCNRNQTSFEEILPRGKREFPIYLIVPDNFFEDSHTINKNQPRLQIDYQMQISIYTTQTGNEPQLIKYQVLNLLVRPNISYLDFLPNIYQEVDFVGRLVGIFEQAFDPVVQTIDTLWAYLDPLTAPTALQNFLAHWVAWDIDSRWDIDKQRQLIRNAITIYRWHGTRYGLRLYLHLYTGLPLDEDSPEVDKHISIQEVFNNGFVLGKTFIGQDSMIGGGRPYHFIVRLRATESLHIDESLVRKIIEQQKPAFSTYELSIINP
>NC_019678.1|WP_015121016.1|6336496_6337048_-|DUF4231-domain-containing-protein
MNSQKKIIDNPIVPAREKALGYAQELIKDYKKTRAISRNLYYGLQIGTIILSGVTPILVLVDKIQASDTWLKWLPVIFPAVASIVASIVTSFPFQENWISANTTVELLEAEQEKFVLGITPLYRCYDSINENEQEKRAKKSIENFITQVNNIHLNQVQQTSSFVSNEDMAEQKEKDKTAQAVT
>NC_019678.1|WP_157229326.1|6339627_6339768_+|hypothetical-protein
MLKEELADAEIGSAELDVLQFGGLEDGYINAVEDIGASEEAGEEED
>NC_019678.1|WP_015121017.1|6340264_6341209_+|nuclease-like-protein
MRATKEKAKAIKGTTVDATVVRVVDGDTVRVEVQGKEESLRILGLDTEESNAGSPKPVSPWGKEAKKEAEKLFKAGDKVKLEFPGDEVVEECMQKYRGNYGRLLVFVYLDDGTDFQEYMIQKGFSPYFMKYGYAALLDNHERYMQAEKEAQIANRGVWNQIEVNGSEVRNYAALGVWWYLRAEIIQNYRQFKQENEDATVFNTRLDYEKVLELAKKEEEATIFTELRNPKRVASNSMLIGIGSVEKPFSIFIPKVDEAAGEKIMSLITNRYISTDEEHPRRSYAYVKGKLSIYRDKPQVIVTNVKQVMDLPQLD
>NC_019678.1|WP_015121018.1|6341350_6341533_-|hypothetical-protein
MFPFWMNSCCGTDSFSTTRHQENKLKFLKFMRDNVEARLAALNAAIETIENQLSRNTDSV
>NC_019678.1|WP_015121019.1|6341684_6343514_-|glycoside-hydrolase-family-15-protein
MGYQPIEDYGIIGNMHTTALVGKNGSIDWFCYPRHDSPSVFAAIIDEHKGGYFKIFPTLCKNTYKQFYWPETNILITRFLADCGVGEVIDFMPVGLSQNDKGYHWLVRKVSCVRSSMKFRMECKPAFNYARDKHETQLTEGGVIFKSDDLNLGLVTDIPLKQDEKGVFAEFSLKEGESAVFILREVECEQGCGLPLNTEETTHIFEHTIDYWRRWISKCTYKGRWREMVERSALMLKLLTYEPTGAIIAAPTCGLPEGIGGERNWDYRYSWIRDSAFTLYALMRIGFTEEAGNFIDWIISLCPSHLENDSQLQIVYGIDGRKNLEEEILDHLEGYKGSSPVRIGNGAYNQTQLDIYGELMDSVYLFNKYGTPISYDTWVNLHKYVEWVCDNWKLEDSGIWETRDGKQDFVYSKLMCWVAVDRGLRLAQKRSFPANREKWLKVRNEIYLDIIENGWNEEKQTFVQYYGSTTLDASNLIMPLVFFMSPNDPRMLKTLDAIMKSPHEGGLLSNSLVYRYNTQDYSDGLEGEEGSFNLCTFWLVEALTRAGRGRDSEKLNKARLIFEEMLSYANHLGLYAEETGTSGEALGNFPQAFTHLALISAACNLDRSI

Crispr_ID: NC_019678_32

• CRISPR_ID: NC_019678_32
• CRISPR_location: 6467626-6467723
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 1 spacers

Consensus repeat of NC_019678_32

Consensus_repeat	Method
AAAATCCATCCGTTATCCAAAACCAACACATTCGTTA	CRISPRCasFinder

spacers of NC_019678_32

>32.1|6467663|24|NC_019678|CRISPRCasFinder
TTCACCAAAAATCCATCCGTTGCC

CRISPR arrays and Neighbor proteins around NC_019678_32

CRISPR arrays

The CRISPR arrays of NC_019678_32

>merge|NC_019678|32|6467626-6467723|CRISPRCasFinder
AAAATCCATCCGTTATCCAAAACCAACACATTCGTTATTCACCAAAAATCCATCCGTTGCCAAAATCCATCCGTTACCAAAATCCATCCGTTACCAAA

>NC_019678|32|29|6467626-6467723|CRISPRCasFinder
AAAATCCATCCGTTATCCAAAACCAACACATTCGTTA	TTCACCAAAAATCCATCCGTTGCC
AAAATCCATCCGTTACCAAAATCCATCCGTTACCAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015121106.1|6459109_6460369_+|hypothetical-protein	unknown	unknown	gnl|CDD|238064
NC_019678.1|WP_015121107.1|6460552_6461431_+|hypothetical-protein	unknown	unknown	gnl|CDD|225011
NC_019678.1|WP_015121113.1|6466424_6467624_+|WD40-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|238121
NC_019678.1|WP_157229463.1|6462058_6462733_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121111.1|6464663_6465854_+|WD40-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|238121
NC_019678.1|WP_044292311.1|6468435_6468837_-|DUF1257-domain-containing-protein	unknown	unknown	gnl|CDD|377725
NC_019678.1|WP_015121119.1|6474296_6475916_-|vanadium-dependent-haloperoxidase	unknown	unknown	gnl|CDD|239492
NC_019678.1|WP_063721473.1|6479003_6481703_-|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|227328
NC_019678.1|WP_015121110.1|6462850_6464410_+|Hsp70-family-protein	unknown	unknown	gnl|CDD|212667
NC_019678.1|WP_015121114.1|6467780_6468188_-|DUF1257-domain-containing-protein	unknown	unknown	gnl|CDD|377725
NC_019678.1|WP_157229329.1|6473453_6473960_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121103.1|6455887_6456184_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197775
NC_019678.1|WP_015121117.1|6471266_6472934_+|Ca2+-binding-protein,-RTX-toxin	unknown	unknown	gnl|CDD|380205
NC_019678.1|WP_015121121.1|6478019_6478499_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121108.1|6461613_6461832_+|DUF2997-domain-containing-protein	unknown	unknown	gnl|CDD|314207
NC_019678.1|WP_015121105.1|6457571_6458936_+|coproporphyrinogen-III-oxidase-family-protein	unknown	unknown	gnl|CDD|181292
NC_019678.1|WP_015121116.1|6468967_6470590_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|177094
NC_019678.1|WP_015121104.1|6456624_6457458_+|sulfatase-like-hydrolase/transferase	unknown	unknown	gnl|CDD|293767
NC_019678.1|WP_015121120.1|6476235_6477753_-|calcium-binding-protein	unknown	unknown	gnl|CDD|380205
NC_019678.1|WP_157229330.1|6481875_6485076_-|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|368641

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015121106.1|6459109_6460369_+|hypothetical-protein	gnl|CDD|238064	cd00116, LRR_RI, Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).	0.00014682
NC_019678.1|WP_015121107.1|6460552_6461431_+|hypothetical-protein	gnl|CDD|225011	COG2100, COG2100, Predicted Fe-S oxidoreductase [General function prediction only].	0.00114891
NC_019678.1|WP_015121113.1|6466424_6467624_+|WD40-repeat-domain-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	7.17274e-62
NC_019678.1|WP_015121117.1|6471266_6472934_+|Ca2+-binding-protein,-RTX-toxin	gnl|CDD|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	3.06055e-09
NC_019678.1|WP_015121111.1|6464663_6465854_+|WD40-repeat-domain-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	9.50505e-68
NC_019678.1|WP_044292311.1|6468435_6468837_-|DUF1257-domain-containing-protein	gnl|CDD|377725	pfam06868, DUF1257, Protein of unknown function (DUF1257). This family contains hypothetical proteins of unknown function that are approximately 120 residues long. Family members include eukaryotic and bacterial proteins.	9.47955e-42
NC_019678.1|WP_015121119.1|6474296_6475916_-|vanadium-dependent-haloperoxidase	gnl|CDD|239492	cd03398, PAP2_haloperoxidase, PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen peroxide forming dioxygen. They are likely to participate in the biosynthesis of halogenated natural products, such as volatile halogenated hydrocarbons, chiral halogenated terpenes, acetogenins and indoles.	1.24015e-77
NC_019678.1|WP_063721473.1|6479003_6481703_-|CHAT-domain-containing-protein	gnl|CDD|227328	COG4995, COG4995, Uncharacterized protein conserved in bacteria [Function unknown].	3.08001e-119
NC_019678.1|WP_015121110.1|6462850_6464410_+|Hsp70-family-protein	gnl|CDD|212667	cd10170, HSP70_NBD, Nucleotide-binding domain of the HSP70 family. HSP70 (70-kDa heat shock protein) family chaperones assist in protein folding and assembly and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). Some HSP70 family members are not chaperones but instead, function as NEFs to remove ADP from their HSP70 chaperone partners during the ATP hydrolysis cycle, some may function as both chaperones and NEFs.	1.48005e-73
NC_019678.1|WP_015121114.1|6467780_6468188_-|DUF1257-domain-containing-protein	gnl|CDD|377725	pfam06868, DUF1257, Protein of unknown function (DUF1257). This family contains hypothetical proteins of unknown function that are approximately 120 residues long. Family members include eukaryotic and bacterial proteins.	1.5751e-30
NC_019678.1|WP_015121108.1|6461613_6461832_+|DUF2997-domain-containing-protein	gnl|CDD|314207	pfam11211, DUF2997, Protein of unknown function (DUF2997). This family of proteins has no known function.	4.36793e-17
NC_019678.1|WP_015121103.1|6455887_6456184_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	1.50675e-07
NC_019678.1|WP_015121105.1|6457571_6458936_+|coproporphyrinogen-III-oxidase-family-protein	gnl|CDD|181292	PRK08208, PRK08208, coproporphyrinogen III oxidase family protein.	0
NC_019678.1|WP_015121116.1|6468967_6470590_-|AAA-family-ATPase	gnl|CDD|177094	CHL00195, ycf46, Ycf46; Provisional.	0
NC_019678.1|WP_015121104.1|6456624_6457458_+|sulfatase-like-hydrolase/transferase	gnl|CDD|293767	cd16148, sulfatase_like, uncharacterized sulfatase subfamily. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases.	2.70678e-15
NC_019678.1|WP_015121120.1|6476235_6477753_-|calcium-binding-protein	gnl|CDD|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	9.2126e-21
NC_019678.1|WP_157229330.1|6481875_6485076_-|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl|CDD|368641	pfam05860, Haemagg_act, haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins.	1.19616e-24

Protein sequences

>NC_019678.1|WP_015121113.1|6466424_6467624_+|WD40-repeat-domain-containing-protein
MSDNQPREYDAVLGGDSQAPVDGVVLGGIEGVKRRLKNPDVKARIAGLYQALNYGDAGLDLVIKALRNEKNLIRATAYIILKQRKEEIAIKTLQGCSDYHFFYCISTLEEHESRVHSVCITPDGQTLISGNPHRIISWEWKTNKSVKTIVTKKDIAFYENDFIRFICINPARKTLFIRSIFGIIKELNWQNPNYDNISNIKNMTRYHALIFDETGNIAFINIKSSIQVWDCFNQKCQGELRANLQPIFSLAMNGKTLFGGSGDNTIKIWNWQKEQLISTLEGHSYWVTSLCISPDGKTLFSGSGDNTIKIWNWQKAELIRTLEGHSLGVNSLAISPDGKTLISASNDTTIKVWNWRTGKLQTTLTGHSAEVNSIVLSPDGKYLFSGSSDKTVKVWGLKE
>NC_019678.1|WP_015121111.1|6464663_6465854_+|WD40-repeat-domain-containing-protein
MSENQPRQYDAVLGGGSQAPVDGVVLGGIEGVKRRWETANIQQKIVALSEALKYGDAGLDFVIQIWQNELGQISYVAYSLLRQKEEAKVKQVLQEYNPWLKIGCVHTLQDINTRCIAIHSNGKVFFDGSNSINTFDLHTGEVEATSMSYVSFGNILISPIKKNIITRGGTSCFDSGIKIWDSQTNERLLFLDENSENVFSLAISPDESKLFCGVNYPGTGISVWNLETAKYIKTLPGHSNHAVQALAITPDGETIISGANDGNVKALNVETGKLIFSLKKQRHSKGVESVAISPDGRTIVSGSKDKTIKVCNLENKKIINTLEGHKGWVYCVAISPDGSTIVSCSRDKTIRIWDLYTGECIRILEGHTDWVYCIAISPDGKTLVSCSRDKTVKIWG
>NC_019678.1|WP_015121110.1|6462850_6464410_+|Hsp70-family-protein
MIVIDFGTSNTIVCTTDTITQQPRTLKFDFLSRRFNEVSVIPSQVFVKSPNNLIFGEPVRSQRLSFSQPQRYFQAFKRDLAADFVPPPRVLDDVNYSAEAISELFLKEIWSHVKQQLEPSRVIFTVPVGAFERYLHWFNGLGEKLDIPQLQIVDESTAAALGYAVKRPGSLVLVVDFGGGTLDLSLVRTVKSNSQSSSVRAEVIAKSDAFVGGIDIDNWIVEDYLRKTNSSREEVGEVGYQNLLEIAERLKMKLSTDNEAKESWFDDENFMSHELQLNSDELADILENRQLLEQLRQTLDEVLAIALSKGIGKADIEKVLLVGGSCQIQAVQQLIISYFGRQKVKLDKPFEAVAHGGLALNEMVEIDDYLRHSYAIRLWEPHSKKYSYMTLIEKGTNYLGDNDKKARIDEPLILQAAIEGQKEIRLDIGEIAEMSQAEVTYDAQGRMTSSHLVKQETYRSLDTQHQQVCIAHLEPPGELGIDRVSVKFGVNEQRMLVATVKDLLTGKALVVREAIAKLK
>NC_019678.1|WP_157229463.1|6462058_6462733_+|hypothetical-protein
MRENKILNWNQLQQKSGLSNSAMWKLRDSDGTSLTLEQLKTTANALNMPLGNFLYKLGILPPHPELESKRRECLQLQQQIEKLNQEKETLRKDGLRLHSELQQQQLELTQEFRKSTFEKLQTLLVNYPSIHQMVNVKPELPAKNLLSGFTPLDNLLKEWDYQPIGKPWQQVEYNPQIHQPDTGDIQQGEKVYIRFIGYQHQGNILSPAKVSRTLPGGRQGDKEK
>NC_019678.1|WP_015121108.1|6461613_6461832_+|DUF2997-domain-containing-protein
MAEYRRVEYRIGKDGKITETVIGASGAGCTETTSGIEDALGKVESQELLPEYYEGEENITSTENQSLKNKNG
>NC_019678.1|WP_015121107.1|6460552_6461431_+|hypothetical-protein
MHLKILYRGSLISCNYGCEYCPFAKRQQSAAELNLDKQQLQRFVDWIIQHPQHQFSILFTPWGEALIHKHYQQALAQLTQMSHVNKVAIQTNLSCNLDWVEDCNKESLALWATFHPEWVSRQSYVSQCLELDKRKVRFSAGVVGFPQYKNEIAALRQELPSHVYLWINAVKKQLSQLSPEDRNFFESIDPLYHLNTHHYPSLGRSCRAGKSMISVDGEGTMRRCHFIKQPIGNIYHQDWEQVLQERDCSNQTCHCHIGYVHLDYLELDKVFGDRILERIPNLTPPSGHPSPY
>NC_019678.1|WP_015121106.1|6459109_6460369_+|hypothetical-protein
MTNNQNQPNQYDAVLGGNAPPPIHGAVLGGIEGVKKRLASSDVDVQIAALNDALNYGDLGLDLVIQALEDNRRKLREAAVYLLEDRNETQAKSALKNYKFWSGFERLYEYPNEYSTTFANRKVIEFDQKIGITDTIDTAYALRANYYSFWEGKEDISIENKLQILQEEPQKHFAEKVEALVFGNSANPDKVIFTVLEKFPNLKAIFIYDIKDDECMISGIPFLSISPILEALPYLEVLKIRGSSSITRGGETWVFNPSIKHNNLKALTIESGGISREVITQFCQLQLPALEYLELWLGDYEYGGTSDIGDIMPIISGKYPKLKYLGLRNSQYSNNIAFALVDSPIIENLIELDLSMGTLTDEGAEALLNCRAIHQLDTLDISENCLSDEMIERLNNLDIEVVNIGYQKHPDERYCTVGE
>NC_019678.1|WP_015121105.1|6457571_6458936_+|coproporphyrinogen-III-oxidase-family-protein
MITNNHPLPTHPLLKSKIFQSYVYSYPHKTAYRPISPQKPLTDVWSQEDKNALFLYIHIPFCEMRCGFCNLFTTVTHNQDFVTQYVNTLQKQAKHVKAALGKSSFARLAIGGGTPTQLPIHHLEAVLNVAEDTMSVDLQQIPISVEMSPETATKDKLELLRSRGVTRASIGVQSFFESEVAAVNRRQTTAEVEAALTRMREAGFPTINIDLIYGLPGQTVETWLQSIRAALQFEPEEIFLYPLYVRPLTGLGTSEKEWDDIRLNCYRQGRDFLLSQGYTQKSMRMFQKNSTPSPHSSPSPHSSPSPIYCCQQDGMVGLGCGARSYTDDLHYSNEYAVGGKGIREILQGYIKTPEDCFDFVNYGFQLDAEEKGRRYILLSLLSHEGLNLHQYQTRFNTELFSDFPELSELIDLNLVVDESRILRLTQTGVEYSDAIGEWLFSAKVRELMQRYELK
>NC_019678.1|WP_015121104.1|6456624_6457458_+|sulfatase-like-hydrolase/transferase
MQNINQIIGTHDIVFITLDTLRYDIATELISQNRTPNLAKVLPNGWEKRHSPGNFTYASHQAFFAGFLPTPVTPGIHPRLFALKFAGSTTTTEKTCVLEGENIVKGLARKGYHTVCIGGVGFFNKQNPLSNVIPSMFAESYWNRELGVTDPKSTENQILLAEKILNKTPQNQRLFLFINISALHQPNFFYLEGAKTDTLETHAAALEYIDRQLGKLWNALQKRASTFCILTSDHGTTYGEDGYTGHRISHPVVWTVPYGEFVLETRETCSQVTPGNA
>NC_019678.1|WP_015121103.1|6455887_6456184_-|helix-turn-helix-transcriptional-regulator
MKKTDDALKILENIHRNDPELQEMVITASINAEVAQLIYEARTQAGLTQKQLADLVGTKQPVIARLEDADYEGHSLSMLQKIASALNKQVKISLTSNV
>NC_019678.1|WP_015121114.1|6467780_6468188_-|DUF1257-domain-containing-protein
MSHFTAIKTQIKDRDALVKALADVGFKNIEVHETAESLYGYQGDVRAETAEVIIRRKYVGSYSNDIGFKLQEDGQYQAIISEFDRGRYNQQWLGKVMQRYGYYSLMASAQEQGFTVEEDEVMEDGTVRVVVARWS
>NC_019678.1|WP_044292311.1|6468435_6468837_-|DUF1257-domain-containing-protein
MSHFTSIKVQIKHGEILHQVLQELGYQVECNTQVRGYHGVTPKAFSSANRTQAEYVIRQNNGYDLGFRRQGENYEIVADFWGAKINQKQFVNSITQKYAHKTLMATVAEQGFNVEEEEVLSDGTVRVVVGSWV
>NC_019678.1|WP_015121116.1|6468967_6470590_-|AAA-family-ATPase
MTNFPEKQSAESKEIPNFELVEQIDLMIRARYPLLYMVAVEEEPLEEVLFKVAALSQPARQVLYWDVVRGWSDNGADKGSVMPALARIGKTDTQKSIIFVLRDLHPYMKNLTTEKSAPIVRELRNLARELKRSRKSIILTSHTLEIPEELKEEVTVVDFPLPDVEQINYLVEQLVVPEKLKLAGLAREQLVKACQGLSRSRIQRVLAKALAAKQQVNESDISGVLAEKKQTIRQTGILEFFTPSESLKRVGGLDQLKQWVQLRQDAFTEEARRYGIPNPKGALLVGIQGTGKSLSAKTIAHEWRLPLLRLDTGRLFGGIVGESESRVRQMIQLTEAMAPCVLWMDEIDKAFGNISSGVDGDSGTSRRVFGSLITWMQEKTSPVFIVATANNVQILPAELLRKGRFDEIFFLNLPTEAERQDILKVHIQKLRPNRVRDFDLTLLASRTENFSGAEIEQVIIEAMHNAFSSKLNGHRRDFITEDILRAIEVTVPLASIAKEQIDALKQWAAQAGARSASNDVQLVEELKQYSSGGISPLEVD
>NC_019678.1|WP_015121117.1|6471266_6472934_+|Ca2+-binding-protein,-RTX-toxin
MKTIIDESQLKSSVDESLLKSSVPSSLYTPNLSLFYNIIIGTPFNDYIPTTFLNDFVVALSGDDRILGSFGNDIIVGGTGKDTADYSNLGQAVTLEAAGVVNKGFFGRDQLYEIETIIGAKGQANAIDGSTGQSRTTSFNVNLAKQSLIVNGIPGLGTAKFQVQNFVNVIGTSQGDTIFGDNYNNVLDGRGGNDTVFGLGGNDTVRGGAGNDVIGGGNKGNIFISRFSDGNDIVEGGSGNDSLIGGTGKDVLDGGSGFDTADYTHLGRAITLEAAGIVNKGFAGTDQILNIEKIVGAKGRANAIDGSTGKSTTTSFNVNLAKESLVVNGIPGIGSAKFQVQNFVDVTGTSQADSIVGNSKNNILEGGRGNDNISGLAGKDTLIGVDSKSFNPGRYEVDILTGGTDADKFVLGNEKSAFYTGGGGFFGLNDFAFITDFEAGEDKLQLKKSESYIFGRNFIAVSNYFKPYPLPYEAASDELLTGGKTSLNNDLDSSVADSAVNDIIKNNGISSTLSLGAETQVAQNSLESSLFIPFPSFDIVAVVADNYSYSDIHFV
>NC_019678.1|WP_157229329.1|6473453_6473960_-|hypothetical-protein
MKNHQQPSRFIAEIAFGTIIAATLFIPVGKAQASNNAIQTNNTITIGSPSNLEASEIKSRQIKSPKLIARRTVNLSGRWRASDGGTYYLKQIGNELWWFGESPNQGATWSNIFHGQIQGKQIAGKWVDVPKGRNNLAGEITLKVLSPNRLRAVRKTGGFGGSVWIRIR
>NC_019678.1|WP_015121119.1|6474296_6475916_-|vanadium-dependent-haloperoxidase
MKFANLAVDFGEVIQTPTIFPDEQGKVEVTITNQGNTNFNGPLNLKLYASTDNELDLKNLNKLDDVSTDQNDLLKGTDELLGTLKQNNIFLAPGESRTLIVDFAGSDFRTASVVSPGLYYLFAEVEPANNITDIDVSDNRSSTLITQGDAVIQWNSILLNTIQATGKNPADGTPPPIAARNQAIVHKAIYDAVLAAPTTSDEAAVVGAASQALIKLFPTQKSTIEGFLNQFLQAIPDSEAKTNGINIGQQAADLIVNQRATDGYNTAQVPFTPGNGIGDWQFTYRDGETTNSKEGDIDEALLPNWGLVTPFVLESGNQFRPFTFPQYNSPFYAQQLNQVQELGAENSTVRNAEQTEIAQFWAYDRSDSFKPPGQWNQIAQEVALDKGNSLEQNAELFAVLNTGLADAGITAWDAKYVYDEIRPITAIREADKDNHPNTIADPTWEPLLDTPPFPDYISGHSVFGGAASTILARFFGDETSFEIPSQELPGVSRSYGSFSQAAYENADSRLFGGVHINAANIDGVTVGQDVGNFVFDNFA
>NC_019678.1|WP_015121120.1|6476235_6477753_-|calcium-binding-protein
MEENLTVEQELKLEVIAERAANQANVRQEAIFEPKLIETVDLQLDKLRQIQSEELRLLETELTSQEQAQIRNLQKLELESQQPKSQALETTTNQISQAQPGNSPEASTNQIATSEARDFPEASTSSQSNVSRFNSGIKIGSPSPDILNGTPADDQILGLAGNDTIFGNDGNDAISGGSENDFIDGNAGNDLIFGDASFSENLDLTGIGNDTLKGGEGNDNIFGQNGEDKLFGGTGNDLLSGGNDNDTLKGGKGNDRIFGQNGEDELRGERGDDVLEGGDGNDLIFGNQGKDTLYGDSFAGEPFSTASGNDTLIAGGGDDLVFGGKGNDNLKGNRGKDELTGGQGNDLLSGGRGQDKLIGTDTVFFAPQQFGFGTGERDTLTGGRGNDTFVLGLAEAKTRQSDGTDGTVEDVVLYDDGNINNNGTQGYALIKDFGFVGDTVIRGVDKIQLAGSESMYSLGTSPIDGTYGTGIFLDEGQNTPELIGVVEGISADTLSFHDSTQFVFV
>NC_019678.1|WP_015121121.1|6478019_6478499_-|hypothetical-protein
MMNLRSHKISLKAALLTTTALVSISSVIFPVSAFAQSQNLNTDLGYQNRPRLWGDVNQDGKQDFCRFVGSRKEEFLSCHLAQGNGFSSNKYGFNSIKGIDRGYDNLPQWMQDVNRDGRDDFCRFVGNGGEIKPVCNLARKSGFDTNQYTLDISSRVRIP
>NC_019678.1|WP_063721473.1|6479003_6481703_-|CHAT-domain-containing-protein
MKSTKRHHKGLFRFIAPMVLSALLCITLPGFAQIPYLSKSPPIQTQNQSGLFLEQQARSHYSKGEFDRAAKLLQQAIQKYDASSNSIRKALSYSNLSLCYQQLGEWNNATNAIVSAINLLTNIDNSNNQIDLALAQALDIQGGLQLARGQANAAIESWKSATAIYSQQNKPLKTLLSQTNQAQALQNLGLYRRAITLLETALKLPSGSTNNPEKLTTLLSDISVSEETATALHTLGNSLRVVGNPKPAQLVLQRSLDIAKQLNLTEIITLSQLALGNIFRAQLMQEKATDNPIDSQAAQTVLNYYQQAATSDSLHLKVYSQVNQLSLLVDTKQIDAAQKLIPQIKQQINSLPPNRHAIETRLHLAHAMIKMSKQKNIISLREIADILAIALQQAQNLSHPRLQANASRLLGNIYEQNKQWVEAEKLTQQALHLSQQEHATDIAYRSQWQLGRIFKAQGKTQRAIDIYQQAVSSIKSLRADLASASPDVQFSFRDEVEPIHRQLVSLLVKSNQKDNFKKARDVIEALQLVELDNFFREPCLKAEPTQIDNVDRTAAVIYPIILEDELAIVASLPKSTSQSQQKSPNKDNRDFRYYKTPITRKQVEQLASNLRDDLQQPTAFDLALPQLQKIYDLLIRPEIADVAAAQVRTLVFVLDGVLRNIPMAALYDGNNFLVEKYSIALTPGLQLLAPRALTKANLEVLVGGLNAERPPFASLPYVKQEVETIKSKLPSKVLFNQKFTNKAFETRVPAVSSPIVHLATHGQFGSTASETFILTWDGKIKVNQLSSILKVGEISRDNPLELLVLSACETAAGDADSALGLAGVAVRSGARSTIATLWRINDEASAKLIGKFYEQLTSANNPGISKAEALRQAQLNILKNPEYRAPYYWAAYVLLGNWM
>NC_019678.1|WP_157229330.1|6481875_6485076_-|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MRKLSNLNWCIFSIASLCAIVSSINKVSAQVIRDETLPKNSEVKVEGNISTIEGGTKSNGNLFHSFKEFSVPTGNEAHFNNAADIQNIITRVTGKSISDIDGLIKANGTANLFLINPNGIVFGENAKLDIGGSFVGSTADSIKFDGDIEFNAINPENKPLLTVNVPLGLQYAQNPGKIEFKGKGEPERKIPRVIEAKTGLEVPANKTLALLGGDVLLEGATLKASSGRIELGSVTGESLVSIAAIEKGFGFGFEKLANIGEKFGDIRLSQNTAVDASGNGAGDIRVTSKNFTITDNSVVVSTQTGTEKSGSIVINAKESVNFDGINDTFIPSGLYANNVSKNRTENTGNIRINAPQFIVNNRATIGANAWSAGNGGDIDIKTNDLRVEGGGIVSAAVFGNGNGGNVNIDASNVQILGTSNDGKSFSELSVSAKKNSTGNTGNMNINTSNLEVAGGALIFAGTSGEGNGGDMTINATESIKIIGRGGNENQFTSGLFVVANEEATGNSGSLTINTNKMQVENFAFVSASNNGKGNAGDLQITTNELLIKDDASLISGVESENKLAGQLTIKTGKLLIEGGSRVNAGATSSDKVNLDIDAQEIQVIGTGNNGKTPSQLSILIQDNLISNAGELNIVTNTLLIKDGAFLFTGTSGKGNGGNLTINAEDIQVIGFGGNNPDNNNQPYFSGLFATAEKNSIGNAGKLNINTKRMLVEDRAFVSTSTNSNNGDGGDLNINANNLQVRNDSKVVSETNSKGTGGNLKITTNNLLVENGGKVSSGTSGAGNAGNLTIDSDAIKVKNDEAQITVESQGRGNAGVLTLNARSINLDNNALLNASTQSSDSSKEQATININSRDLILHRRSNIFTNAKGEQVIGGNINIKTDFLIAGENSDISANSENFRGGNVRIDAQGIFGTEFRDRPSDSTSDITATGASPDLAGIVEIITPQSDPNNGLVELPTIPIYPEIADTCSTPSYAQSSFTITGAGSLPPSPFKPLTGNLNRTSLVTLAGEIKPPVRRSRQAPKQKQEIKQIVDAQGWVRTKDGKIILVKNATQNSNFLAMKNSAHCN

Crispr_ID: NC_019678_33

• CRISPR_ID: NC_019678_33
• CRISPR_location: 6751356-6752970
• CRISPR_type: TypeV
• Repeat_type: A:N
• Spacer_info: 22 spacers

Consensus repeat of NC_019678_33

Consensus_repeat	Method
GTTGAAACTCACCTTAATCCCTATTAGGG----------ATTGAAAC	PILER-CR
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	CRISPRCasFinder
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	CRT

spacers of NC_019678_33

>33.1|6751393|36|NC_019678|PILER-CR,CRISPRCasFinder,CRT
ATAACGAGGCAGAACAAGCAAGAAAGCAATTAAAAA
>33.2|6751466|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
ATTGAATTGTAGTGTTGTAATGTTGTATGTAAAT
>33.3|6751537|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AATCGGGCAATGGCAAATGATTCACAACAATGGG
>33.4|6751608|38|NC_019678|PILER-CR,CRISPRCasFinder,CRT
ACCTTTAAGAACAGTGAAGTTGCTAAGGACTTGTTTAG
>33.5|6751683|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TATGGTACGCTCTTTTTCTTGCTTGGGATTAATAG
>33.6|6751755|38|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTAATCTATTTTCTATCTTGCCGCTAGAATGATTAAAA
>33.7|6751830|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TAATTATCGCGTTAAGGTTAAGGAATTGTTTACAA
>33.8|6751902|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TATTTAGGATGCTTTACCACGGCATCCTTTTTG
>33.9|6751972|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AAGGAAGAGAGTATAGATACAGTTTGCAATCAG
>33.10|6752042|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AACAAGCCTCAAACCTAGTGATAGCAGTCAATTGT
>33.11|6752114|36|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CTTATCCTACAAACATGACTACATTTTCTTCTGCTC
>33.12|6752187|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CTATTATGGGAAGGGGGAGGATTTCTATTATCTC
>33.13|6752258|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AATTACATCCTGTATTTGCTCTTTCTTTGAATTA
>33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
ATCAGTCTTTAATTAGATATAATCATTTAAAACAA
>33.15|6752401|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT
ATATTCTTGCTGCAATTTCAGGATGCACTGTAT
>33.16|6752471|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTCAATCGCCTTAAAGGAGTCTTTAAACGCTTTA
>33.17|6752542|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTTTAACTTCTAGAGAAGCTTTCTCAGATTCTC
>33.18|6752612|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GATGATTTTAGACATTTGAATAGTTTGAAGAATA
>33.19|6752683|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GGTACTTTGAAAGTTTGTGAGGAGAATGAAATACT
>33.20|6752755|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GCATCAACCAACTTTCCTTACTGCCATTAGCTGAT
>33.21|6752827|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTATAAGAATTTGTGTAAGCATTATGGAAAAGTAG
>33.22|6752899|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CATAACCTCTCAAGATAAACCTCTGAGGAGAAAAA

CRISPR arrays and Neighbor proteins around NC_019678_33

CRISPR arrays

The CRISPR arrays of NC_019678_33

>merge|NC_019678|33|6751356-6752970|PILER-CR,CRISPRCasFinder,CRT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACATAACGAGGCAGAACAAGCAAGAAAGCAATTAAAAAGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACATTGAATTGTAGTGTTGTAATGTTGTATGTAAATGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACAATCGGGCAATGGCAAATGATTCACAACAATGGGGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACACCTTTAAGAACAGTGAAGTTGCTAAGGACTTGTTTAGGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACTATGGTACGCTCTTTTTCTTGCTTGGGATTAATAGGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACTTAATCTATTTTCTATCTTGCCGCTAGAATGATTAAAAGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACTAATTATCGCGTTAAGGTTAAGGAATTGTTTACAAGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACTATTTAGGATGCTTTACCACGGCATCCTTTTTGGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACAAGGAAGAGAGTATAGATACAGTTTGCAATCAGGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACAACAAGCCTCAAACCTAGTGATAGCAGTCAATTGTGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACCTTATCCTACAAACATGACTACATTTTCTTCTGCTCGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACCTATTATGGGAAGGGGGAGGATTTCTATTATCTCGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACAATTACATCCTGTATTTGCTCTTTCTTTGAATTAGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACATCAGTCTTTAATTAGATATAATCATTTAAAACAAGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACATATTCTTGCTGCAATTTCAGGATGCACTGTATGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACTTCAATCGCCTTAAAGGAGTCTTTAAACGCTTTAGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACTTTTAACTTCTAGAGAAGCTTTCTCAGATTCTCGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACGATGATTTTAGACATTTGAATAGTTTGAAGAATAGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACGGTACTTTGAAAGTTTGTGAGGAGAATGAAATACTGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACGCATCAACCAACTTTCCTTACTGCCATTAGCTGATGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACTTATAAGAATTTGTGTAAGCATTATGGAAAAGTAGGTTGAAACTCACCTTAATCCCTATTAGGGATTGAAACCATAACCTCTCAAGATAAACCTCTGAGGAGAAAAAGTTGAAACTCACCTTAATCCCTATTAGGAATTAAAAC

>NC_019678|33|15|6751356-6752970|PILER-CR
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	ATAACGAGGCAGAACAAGCAAGAAAGCAATTAAAAA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	ATTGAATTGTAGTGTTGTAATGTTGTATGTAAAT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	AATCGGGCAATGGCAAATGATTCACAACAATGGG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	ACCTTTAAGAACAGTGAAGTTGCTAAGGACTTGTTTAG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TATGGTACGCTCTTTTTCTTGCTTGGGATTAATAG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TTAATCTATTTTCTATCTTGCCGCTAGAATGATTAAAA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TAATTATCGCGTTAAGGTTAAGGAATTGTTTACAA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TATTTAGGATGCTTTACCACGGCATCCTTTTTG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	AAGGAAGAGAGTATAGATACAGTTTGCAATCAG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	AACAAGCCTCAAACCTAGTGATAGCAGTCAATTGT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	CTTATCCTACAAACATGACTACATTTTCTTCTGCTC
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	CTATTATGGGAAGGGGGAGGATTTCTATTATCTC
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	AATTACATCCTGTATTTGCTCTTTCTTTGAATTA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	ATCAGTCTTTAATTAGATATAATCATTTAAAACAA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	ATATTCTTGCTGCAATTTCAGGATGCACTGTAT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TTCAATCGCCTTAAAGGAGTCTTTAAACGCTTTA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TTTTAACTTCTAGAGAAGCTTTCTCAGATTCTC
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	GATGATTTTAGACATTTGAATAGTTTGAAGAATA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	GGTACTTTGAAAGTTTGTGAGGAGAATGAAATACT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	GCATCAACCAACTTTCCTTACTGCCATTAGCTGAT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TTATAAGAATTTGTGTAAGCATTATGGAAAAGTAG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	CATAACCTCTCAAGATAAACCTCTGAGGAGAAAAA
GTTGAAACTCACCTTAATCCCTATTAGGAATTAAAAC

>NC_019678|33|30|6751356-6752970|CRISPRCasFinder
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	ATAACGAGGCAGAACAAGCAAGAAAGCAATTAAAAA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	ATTGAATTGTAGTGTTGTAATGTTGTATGTAAAT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	AATCGGGCAATGGCAAATGATTCACAACAATGGG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	ACCTTTAAGAACAGTGAAGTTGCTAAGGACTTGTTTAG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TATGGTACGCTCTTTTTCTTGCTTGGGATTAATAG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TTAATCTATTTTCTATCTTGCCGCTAGAATGATTAAAA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TAATTATCGCGTTAAGGTTAAGGAATTGTTTACAA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TATTTAGGATGCTTTACCACGGCATCCTTTTTG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	AAGGAAGAGAGTATAGATACAGTTTGCAATCAG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	AACAAGCCTCAAACCTAGTGATAGCAGTCAATTGT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	CTTATCCTACAAACATGACTACATTTTCTTCTGCTC
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	CTATTATGGGAAGGGGGAGGATTTCTATTATCTC
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	AATTACATCCTGTATTTGCTCTTTCTTTGAATTA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	ATCAGTCTTTAATTAGATATAATCATTTAAAACAA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	ATATTCTTGCTGCAATTTCAGGATGCACTGTAT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TTCAATCGCCTTAAAGGAGTCTTTAAACGCTTTA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TTTTAACTTCTAGAGAAGCTTTCTCAGATTCTC
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	GATGATTTTAGACATTTGAATAGTTTGAAGAATA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	GGTACTTTGAAAGTTTGTGAGGAGAATGAAATACT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	GCATCAACCAACTTTCCTTACTGCCATTAGCTGAT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TTATAAGAATTTGTGTAAGCATTATGGAAAAGTAG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	CATAACCTCTCAAGATAAACCTCTGAGGAGAAAAA
GTTGAAACTCACCTTAATCCCTATTAGGAATTAAAAC

>NC_019678|33|14|6751356-6752970|CRT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	ATAACGAGGCAGAACAAGCAAGAAAGCAATTAAAAA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	ATTGAATTGTAGTGTTGTAATGTTGTATGTAAAT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	AATCGGGCAATGGCAAATGATTCACAACAATGGG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	ACCTTTAAGAACAGTGAAGTTGCTAAGGACTTGTTTAG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TATGGTACGCTCTTTTTCTTGCTTGGGATTAATAG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TTAATCTATTTTCTATCTTGCCGCTAGAATGATTAAAA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TAATTATCGCGTTAAGGTTAAGGAATTGTTTACAA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TATTTAGGATGCTTTACCACGGCATCCTTTTTG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	AAGGAAGAGAGTATAGATACAGTTTGCAATCAG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	AACAAGCCTCAAACCTAGTGATAGCAGTCAATTGT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	CTTATCCTACAAACATGACTACATTTTCTTCTGCTC
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	CTATTATGGGAAGGGGGAGGATTTCTATTATCTC
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	AATTACATCCTGTATTTGCTCTTTCTTTGAATTA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	ATCAGTCTTTAATTAGATATAATCATTTAAAACAA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	ATATTCTTGCTGCAATTTCAGGATGCACTGTAT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TTCAATCGCCTTAAAGGAGTCTTTAAACGCTTTA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TTTTAACTTCTAGAGAAGCTTTCTCAGATTCTC
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	GATGATTTTAGACATTTGAATAGTTTGAAGAATA
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	GGTACTTTGAAAGTTTGTGAGGAGAATGAAATACT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	GCATCAACCAACTTTCCTTACTGCCATTAGCTGAT
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	TTATAAGAATTTGTGTAAGCATTATGGAAAAGTAG
GTTGAAACTCACCTTAATCCCTATTAGGGATTGAAAC	CATAACCTCTCAAGATAAACCTCTGAGGAGAAAAA
GTTGAAACTCACCTTAATCCCTATTAGGAATTAAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015121298.1|6741224_6742001_+|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl|CDD|179028
NC_019678.1|WP_015121307.1|6754050_6754452_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_085977731.1|6747819_6748314_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121302.1|6746637_6747585_-|ribonuclease-Z	unknown	unknown	gnl|CDD|274246
NC_019678.1|WP_015121308.1|6755095_6755509_+|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl|CDD|223149
NC_019678.1|WP_015121313.1|6759351_6760293_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|133005
NC_019678.1|WP_015121299.1|6742473_6743247_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|378925
NC_019678.1|WP_015121304.1|6748343_6749543_-|alanine-dehydrogenase	unknown	unknown	gnl|CDD|240623
NC_019678.1|WP_157229469.1|6744961_6745186_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121311.1|6757296_6758097_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121300.1|6743682_6744849_+|SpoIID/LytB-domain-containing-protein	unknown	unknown	gnl|CDD|225259
NC_019678.1|WP_015121315.1|6761089_6764209_-|DUF3854-domain-containing-protein	unknown	unknown	gnl|CDD|372412
NC_019678.1|WP_015121314.1|6760393_6760984_+|colanic-acid-biosynthesis-acetyltransferase-WcaF	unknown	unknown	gnl|CDD|236703
NC_019678.1|WP_015121297.1|6740341_6741013_-|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|215413
NC_019678.1|WP_015121301.1|6745070_6746351_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121309.1|6755837_6756272_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_044292367.1|6756430_6756970_-|bifunctional-adenosylcobinamide-kinase/adenosylcobinamide-phosphate-guanylyltransferase	unknown	unknown	gnl|CDD|235612
NC_019678.1|WP_015121306.1|6752990_6754007_-|tRNA-dihydrouridine-synthase-family-protein	unknown	unknown	gnl|CDD|239200
NC_019678.1|WP_015121312.1|6758282_6759212_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|366154
NC_019678.1|WP_015121305.1|6749694_6750819_-|site-2-protease-family-protein	unknown	unknown	gnl|CDD|100085

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015121298.1|6741224_6742001_+|glucosamine-6-phosphate-deaminase	gnl|CDD|179028	PRK00443, nagB, glucosamine-6-phosphate deaminase; Provisional.	7.53882e-102
NC_019678.1|WP_015121302.1|6746637_6747585_-|ribonuclease-Z	gnl|CDD|274246	TIGR02651, Ribonuclease_Z, ribonuclease Z. Processing of the 3-prime end of tRNA precursors may be the result of endonuclease or exonuclease activity, and differs in different species. Member of this family are ribonuclease Z, a tRNA 3-prime endonuclease that processes tRNAs to prepare for addition of CCA. In species where all tRNA sequences already have the CCA tail, such as E. coli, the need for such an enzyme is unclear. Protein similar to the E. coli enzyme, matched by TIGRFAMs model TIGR02649, are designated ribonuclease BN. [Transcription, RNA processing].	4.1568e-153
NC_019678.1|WP_015121308.1|6755095_6755509_+|Hsp20/alpha-crystallin-family-protein	gnl|CDD|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	3.80332e-27
NC_019678.1|WP_015121297.1|6740341_6741013_-|HAD-IA-family-hydrolase	gnl|CDD|215413	PLN02770, PLN02770, haloacid dehalogenase-like hydrolase family protein.	9.91565e-47
NC_019678.1|WP_015121304.1|6748343_6749543_-|alanine-dehydrogenase	gnl|CDD|240623	cd05199, SDH_like, Saccharopine Dehydrogenase like proteins. Saccharopine Dehydrogenase (SDH) and related proteins, including bifunctional lysine ketoglutarate reductase/SDH enzymes and N(5)-(carboxyethyl)ornithine synthases. SDH catalyzes the final step in the reversible NAD-dependent oxidative deamination of saccharopine to alpha-ketoglutarate and lysine, in the alpha-aminoadipate pathway of L-lysine biosynthesis. SDH is structurally related to formate dehydrogenase and similar enzymes, having a 2-domain structure in which a Rossmann-fold NAD(P)-binding domain is inserted within the linear sequence of a catalytic domain of related structure. Bifunctional lysine ketoglutarate reductase/SDH protein is a pair of enzymes linked on a single polypeptide chain that catalyze the initial, consecutive steps of lysine degradation. These proteins are related to the 2-domain saccharopine dehydrogenases.	1.7905e-179
NC_019678.1|WP_015121313.1|6759351_6760293_+|glycosyltransferase-family-2-protein	gnl|CDD|133005	cd02511, Beta4Glucosyltransferase, UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide. UDP-glucose: lipooligosaccharide (LOS) beta-1-4-glucosyltransferase catalyzes the addition of the first residue, glucose, of the lacto-N-neotetrase structure to HepI of the LOS inner core. LOS is the major constituent of the outer leaflet of the outer membrane of gram-positive bacteria. It consists of a short oligosaccharide chain of variable composition (alpha chain) attached to a branched inner core which is lined in turn to lipid A. Beta 1,4 glucosyltransferase is required to attach the alpha chain to the inner core.	1.63675e-82
NC_019678.1|WP_015121300.1|6743682_6744849_+|SpoIID/LytB-domain-containing-protein	gnl|CDD|225259	COG2385, SpoIID, Sporulation protein and related proteins [Cell division and chromosome partitioning].	3.87926e-111
NC_019678.1|WP_015121315.1|6761089_6764209_-|DUF3854-domain-containing-protein	gnl|CDD|372412	pfam12965, DUF3854, Domain of unknown function (DUF3854). A family of uncharacterized proteins found by clustering human gut metagenomic sequences. This domain is likely to be related to the Toprim domain.	6.89339e-54
NC_019678.1|WP_015121314.1|6760393_6760984_+|colanic-acid-biosynthesis-acetyltransferase-WcaF	gnl|CDD|236703	PRK10502, PRK10502, putative acyl transferase; Provisional.	1.28217e-112
NC_019678.1|WP_015121299.1|6742473_6743247_-|ABC-transporter-permease	gnl|CDD|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	3.50949e-05
NC_019678.1|WP_015121312.1|6758282_6759212_+|glycosyltransferase-family-2-protein	gnl|CDD|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	1.37415e-30
NC_019678.1|WP_015121305.1|6749694_6750819_-|site-2-protease-family-protein	gnl|CDD|100085	cd06164, S2P-M50_SpoIVFB_CBS, SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation. In this subgroup, SpoIVFB (sporulation protein, stage IV cell wall formation, F locus, promoter-distal B) contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain. SpoIVFB is one of 4 proteins involved in endospore formation; the others are SpoIVFA (sporulation protein, stage IV cell wall formation, F locus, promoter-proximal A), BofA (bypass-of-forespore A), and SpoIVB (sporulation protein, stage IV cell wall formation, B locus). SpoIVFB is negatively regulated by SpoIVFA and BofA and activated by SpoIVB. It is thought that SpoIVFB, SpoIVFA, and BofA are located in the mother-cell membrane that surrounds the forespore and that SpoIVB is secreted from the forespore into the space between the two where it activates SpoIVFB. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown.	5.02496e-80
NC_019678.1|WP_015121306.1|6752990_6754007_-|tRNA-dihydrouridine-synthase-family-protein	gnl|CDD|239200	cd02801, DUS_like_FMN, Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also in some archaea. Most dihydrouridines are found in the D loop of t-RNAs. The role of dihydrouridine in tRNA is currently unknown, but may increase conformational flexibility of the tRNA. It is likely that different family members have different substrate specificities, which may overlap. 1VHN, a putative flavin oxidoreductase, has high sequence similarity to DUS. The enzymatic mechanism of 1VHN is not known at the present.	4.97487e-85
NC_019678.1|WP_044292367.1|6756430_6756970_-|bifunctional-adenosylcobinamide-kinase/adenosylcobinamide-phosphate-guanylyltransferase	gnl|CDD|235612	PRK05800, cobU, adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Validated.	1.1846e-80

Protein sequences

>NC_019678.1|WP_015121305.1|6749694_6750819_-|site-2-protease-family-protein
MNNTIRVGNLFGIPFYIHPSWFLVLGLVTWTYGSGLGNAFPYLGSGSALLLGLMTALMVFGSVVAHELGHSFVAIRQGIDVKSITLFIFGGLASLEKESNTPASAFWVAIAGPLVSLLLFGVFAVIGFGTAASGVFSAILSVLAAVNLALFAFNLIPGLPLDGGNILKAIVWKITGNPNKGVVFASRVGQIFGWIAIASGLIPLLLTGSFANFWNLLIGFFLLRNAGNAAQVARVQEQFTGLTAGDAVSSDSPIVADNLTLREFADEQIVTGQKWRRFLVTNSDGQLVGAISAECFRTVSPQLWSETLIKDVMRPIAESTTVKADQPLLEVVQLIEQQKLSALTVIRDNNVLVGILEKSAILSLLQKRMLSNPA
>NC_019678.1|WP_015121304.1|6748343_6749543_-|alanine-dehydrogenase
MKVGIIREGKTKSDTRVPLTPKQCRYLLETYRDLQIFVQPSQERCFSNEEYQNQGIPIKENMEECELLLGVKEVPISMLIPQKTYLFFSHTIKKQPYNRELLRSILQQKIRLIDYECLTDEYGKRVIAFGRWAGIVGGHNAILAWGRREGKFNLKPMHECHDWAEAQTYYQNLPLSNIKLVVTGEGRVASGAVEVLEKMKIKRVSPQEFLEHNSSEPVYTQLAVKDMYRFAGEQNFDDSHYYQHPEEYVSSFAPYTRTANIMLNGIYWDKRIPAFFSKEDMKRKDFTIRVIADVTCDIAPDSSIPSTIKASSITNPIYGYDPLLSKETEPFQNHCIDVMAVDNLPNELPRDASQDFGNQLISKVWSQLNQADSRMIYEGTIAFNGRLNKPYEYLKDYVS
>NC_019678.1|WP_085977731.1|6747819_6748314_+|hypothetical-protein
MKLFSLLFSAAIAGCTNVTTSQYEATALTTYTWQVKYANNLNSEPSPRREEFATTSLLNRNGLKPSAAVTGPDDRGLWWPALPPRPTVDEVEQRQGSEQEASRPELLKSVKYEFIYSEGTEQRTLPTDYDVYRQVVKAYPERVPLELTLGVGDNSVEKAEPVSQ
>NC_019678.1|WP_015121302.1|6746637_6747585_-|ribonuclease-Z
MQITFLGTSSGVPTRSRNVSSVALRLPQRAELWLFDCGEGTQHQILRSDLKMSQLSRIFVTHMHGDHIFGLMGLLASCGLAGNVSRVDIYGPQGLNEYLQACRRYSHTHFSYPVKVHAVRPGVVYEDSEFRVSCDILHHRITAYGYRVEEKNRAGRFDVEKAKALEIPPGRIYGQLKRGESVTLKDGRVINGADLCGPTEIGRKVVYCTDTVFCENAVDLAKDADVLIHEATFAHQDSQMAFDRLHSTSTMAAQTALAAGAHNLIMSHFSPRYAPGNAIELKDLLNEGRAIFPNTKMAYDFMTYDVPRRRESVRS
>NC_019678.1|WP_015121301.1|6745070_6746351_-|hypothetical-protein
MAPNPAIMQAVEKLNYRVTVGDVAQKAGLNIEITNQGLLALATDAGGHLQVADTGDIVYLFPRNFRDVLRNKYFKLQLQEWWNKVWKVLFYLIRISFGIVLILSIALIVISITLILTSLSGDDDDRGGGFGGGIGFFYFPDLFWFFSPNYNTGYRSHGRRREKSDLNFLEAVFSFLFGDGNPNVNLEERRWQEIATVIRNNDGAVVAEQITPYLDNIGETYQQQYEDYMLPVLTKFNGKPEVSPEGEIVYYFPELQVSAKNNHRQSIPNFLREFSWRFSKATSSQVMLSTGLGVVNFVGALMLGGLLRDGTIAGGLVGFVQGIYGLLLVYAIGFLAIPLIRYFWVQWRNEKISDRNRQRQSRANLISSADEKLQKKIDYAHQFATSTVISEENLTYSTETDLIEQEAQRSEQIDAEWRKRLEEGNG
>NC_019678.1|WP_157229469.1|6744961_6745186_+|hypothetical-protein
MKNYRTHSYHNFLLPITNYPLPITHYQFPITHYQFPITHYLLQVVSAILHRFARNVVLLVRLNRFRYCRLNSLR
>NC_019678.1|WP_015121300.1|6743682_6744849_+|SpoIID/LytB-domain-containing-protein
MKFRLNNPSMLSQIKIRHWWLGVLLWMFLIVPAQASVIMRVAIKRDVKQVKVGSSTTAVIKDGSGNSLGTLPAREAYYAQAVSGQVALDKWKSPLFWIEPKGKGFVYIGNRWYRGRTLVIPTEKGLTAVNWIDLEEYLYSVLGGEMDARWHPEALKAQAIAARSYALYRRQREQANPLFDVGNTPDKWQIYKGVVAEHPAIYAAVDGTSGQVLTHNNQIIESVFHACSGGHTENVEDVWGNSLPYLRAVPDFDLNTPNLAKIAPKCQWQKSFSSSQISKKFPEVGNVTQMKPVELSPFNSVKKLRIIGEKGTKELKGEQVRTALKLNSTRFVVNKGENNTFVLQGRGWGHGLGMSQYGARYLATQGYNHLQILNHYYRNVALAPIQVK
>NC_019678.1|WP_015121299.1|6742473_6743247_-|ABC-transporter-permease
MLKLFFAELRCSWIEFRRYPIESISQIVIVSTIFYGLFLGAGYIVGSNLQLGDRLDSIVVGYVLWILVNFVMTNIAGKIQYEAQTGTLEQLFLSRYSAVKVFLMRGLAYLTLEILKIILIIFIIIALTGSSLYFPPVLVLPFICVLLGAYGFAFIIGSLALILKRVQQLIPLLLFPLLFLLTIPTETWTGNPKLFAQLIPMTPGAGLLRDLMARGEALNLATLSIAFINGIIYFTIGLLLFRFAEKEAKRKGILSGY
>NC_019678.1|WP_015121298.1|6741224_6742001_+|glucosamine-6-phosphate-deaminase
MSNAKKDFRVDSLGVQIYNSEDELALSTATIVQQYLLSILEKKQTATVIFATGNSQLKFLDFLVKFNNIDWSKIICFHLDEYLGISANHSSSFRYYLRKRIEKLISPQKFNYIEGDTLEPLRECDRYSKLLATQPVDLCMLGIGENGHLAFNEPSVADFDDAYKVKLVKLDSVNHQQQVDEGHFPNLESVPKYAFTLTIPTICTAKKIICLAPGKRKAKVVKQLLQGNITEQFPASILRKQSQASLLLDVDAASLIDN
>NC_019678.1|WP_015121297.1|6740341_6741013_-|HAD-IA-family-hydrolase
MLTAILFDLDGTIVNTDPIHYQIWYGILLEYHIKINENIYKSNITGRLNPDIIRDLLPHLSQKEIESFAEEKEARFREQASLLKPIKGFAKLLTWSKQHHLKSALVTNAPKLNAYFMLEVLQLKEAFDIVILAEEEVAAKPDPTPYKVALERLGVNARETIAIEDSPSGIRSSVSAGIRTVGMTSTQTSETLEGFGAFATISDFTNLQLWTFLNSQLAENHEV
>NC_019678.1|WP_015121306.1|6752990_6754007_-|tRNA-dihydrouridine-synthase-family-protein
MSQVSLPKSLYPDLPLTALAPMQDVTNLWFMKILAQYGSPDYFFTEYFRVRDDSRLNRKILASITENDTERPVFAQMIGESIPDLVRTARELCQYNIAGIDLNMGCPAPRVYRKNVGGGLLREPEKVNRILGELRSAINDRPLTVKMRVGFDNTDNFEEILDIINRHNIDLLSLHGRTVKEMYRGQVKYDLISQAVKRVNCPVLANGNIDSAATALKVLSQTGAAGVMVGRWAIANPWIFNQIRLRLRSEPIPLVPLVEVREYIDRLRQTPEAVKTPPRARAGHLKMYLNYIALLVDAEGHFLRLMRKTQTELELLKLCDRVLLDSNKNLALAPYSSD
>NC_019678.1|WP_015121307.1|6754050_6754452_-|hypothetical-protein
MEQLKSLLSMTLDELTEYSTDARKIEKLRRKICLALPMAEQRKAKEELLTQMPSGELNRIIEEQRQTVALPFWGIGGLGLLLGISLHQPIGLLAAIGGTFAAIKIQKLGWEMQAKRLLLQTLEDIEVRANQPK
>NC_019678.1|WP_015121308.1|6755095_6755509_+|Hsp20/alpha-crystallin-family-protein
MAITRYNPWGEMNTLQNQLDRLFEDIQAPAFRTPAAELTETEDALHLRFELPGIEAKDVDIEVTADAVKVIAERKSEQKEDTRSEFYYGKYQRVIPLKARIKNTDVTAEYKDGILNLTLPKAEEEKNKVVKVSLSES
>NC_019678.1|WP_015121309.1|6755837_6756272_-|hypothetical-protein
MASKTQVKKYLAYWFQLGKKVIISNGVASLQPLNVIDGESYSKDFEECWQKILSPKSGECYLEGTEQTVAELLSPEWDISCCSRCEMPVPLKNLGMPAILCPCNDVLNWPNTELPAPREPVNSQNQLTKIRQRLLFNKESEFAD
>NC_019678.1|WP_044292367.1|6756430_6756970_-|bifunctional-adenosylcobinamide-kinase/adenosylcobinamide-phosphate-guanylyltransferase
MSKVILVTGPARSGKSEWAEALANQSSKKVVYVATALLSPNDKQWQQRIIQHRNRRPETWLTLEVPFDLSATLSDAKPDTVILVDSLGTWVANHLDKDDKSWLDIVEEFLEIVQLVAAEMIFVAEETGWGVVPAYPIGQTFRDRLGSLTRKLGVICQTAYLVTGGHVINLSVLGSRLPC
>NC_019678.1|WP_015121311.1|6757296_6758097_+|hypothetical-protein
MKAGLKRIEETLQDLDIRITNPLNENAEADGLNQQSLSFRIQDRASESNQELTELSSEELLENNPSQEVLEDLSEDNSVQTFSAQDEEIKAPSLPKFKTPSFSSHRNAPNPALASNVLQEIQEIVAGWQTELYKILRQIQDIYSQGPIVNGWLESHEKEPQPEATATLRHAEVDRLMDYVEEICAAQETPNPSDFSRTGYRLCGLDASGEVWSRSCPAEEVPGVSMAIARYQKLRQYLERKQKLENRLNQLAETLVVLHGHIKQQK
>NC_019678.1|WP_015121312.1|6758282_6759212_+|glycosyltransferase-family-2-protein
MPDTQISAIICTHNRDDYLGAAIDSLLSQDFAGGFEVVVIDNGSKDNTKQVVEQRLDNHLLKYIYEPKLGLSVARNTGAKASSGEVIAYLDDDAVASKSWLQVLYRAYQSNSKLAIAGGKVTLLWPDKVNPPRWLSSGLAGNLGAYDLGDRVVKIENPGDTPRGLNYSIRRSFLDDIGGFDINLGRVGKNLLSNEELQMTELALKKGWEVAYLPEALAAHNVSPERLKRSWFISRGWWQGISECYREQLAGKAGTGQLQRGGERFIRGLYKALQHYSDPAERFDKLVYAYGQIGYLNAAIQGLLSKKSS
>NC_019678.1|WP_015121313.1|6759351_6760293_+|glycosyltransferase-family-2-protein
MSSKIPVSVLIPAKNEEANLPACLKSVSRADEVFVVDSQSTDRSIEISENLGATVVQFEFNGGWPKKKNWSLENLPFRNEWVLIVDCDERITPELWDEIAQAIENPEYSGYYLNRRVFFLGKWIRHGGKYPDWNLRLFKHKEGRYENLNTEDIPNTGDNEVHEHVVLSNKVGYLKEDMLHEDFRDLYHWLARHNRYSNWEARVYYNLLTGKGDDGTIGASLFGDAVQRKRFLKKIWVRLPFKPLLRFLLFYIIQRGFLDGRAGYIYGRLLSQYEYQIGVKLYELRSCGGSLNTVNASKNPQPAIGAEVSQSAT
>NC_019678.1|WP_015121314.1|6760393_6760984_+|colanic-acid-biosynthesis-acetyltransferase-WcaF
MSNAQCPISTTLNAEPFVDLRKYDQSDFDRGRAGWYILLWWFVQAITFPLTLHNMSGIRCAILRLFGARIGKGVLIRPTARFTYPWKVTIGDYSWIGDDVVLYSIDEINIGSHCVISQKSYICTGSHDIKDPAFGLQTAKVAIGNGAWIATDCFVGLGVTIGANAVIGARSSVLTDMPDEQVCWGTPCRPRYARNR
>NC_019678.1|WP_015121315.1|6761089_6764209_-|DUF3854-domain-containing-protein
MHLHYLKPEHLEELVNGSGIDLHLVKLNFRSLEDKNAYDYLFISELIPRTNTGIVKSYWLERYAHVSAGGWWCSGVDMLNNWHMMEWGCFKPNQPRINEKGKSIKYEHPPCTPTRIFCLRVPLPMWEQVAQRYHVQLPDNVAIAEDGGAVGFWQWVMERNIPVIICEGVKKAATLLSQGYAAIAIPGITSGYRVVKNKFGKVIRRQLIADLAAFCITKRTIYICFDFETELKKTNAVNNAISQLGLLFQEKNCPVQVIELPGMEKGVDEFIVAKGAAAFDKIYYQSPDLEIYLAHSKPHTNLTIPAAMTVNRRYLGEIPFPTSGLVGVKSAKGTGKTTALQAVVQQALNRNKPILLITHRIQLGRFLCEKVGIKWGVGYKEWGIQNCKNISSSDVLLPNIAASEHHSPNTGLCIDSIWKLNPSDWEGAIIILDEVEQSLWHLLHSTTCKDKRVKILKLFQQLISTVLTTGGLVIAQDADLSDVSLEYLQRLAGIELTPWVVVNQWKPEQAWDITFYDSPNPTPLIQQLELDLLAGRKCYITTDSRSGRYSSETIERYLKERLDKLRHLYPKTLIVSSHTTNTPGHEAVDFVASINQKITEYDAVFVTPSLGTGISIDVQHFDRVYGIFQGVIPDSEARQALARVRDDVPRVVWCAKRGVGLIGSGSKNYRQLSFWYQENQKENLALLSPTHKIDVDLPLVYDPIHLRTWAKLSARVNASINFYRQSMKEGLTAEGHNLWVRTNDIQKNIIRDLRYAFLATDKEDSANRRRLILEIVKAKKDWEQSRNKSQEINNNIKKIKQQNQLAAATAVSQAPDINYLEYELLLKKHSLTDNERHKINKYFLRKRYGIEVTPQLKLQDDRGYYYQLRTHYYLTHSSDYFHIRDKQEWNQQLSCGEGKVFLPDLKIYTLRIEALRALGVLQLLEPSREFTENDAELILLKNTVLQCSRHIQRALNINLVVENEQVSTIKIIRRLFNLLGLKLKRENNIYRIDRETVNDGRDKIFSVWCQRDELMLTHLKNVADSQVDVRNFSLQGSTL

Crispr_ID: NC_019678_34

• CRISPR_ID: NC_019678_34
• CRISPR_location: 6795034-6795185
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 1 spacers

Consensus repeat of NC_019678_34

Consensus_repeat	Method
TAACCTCACCCCGCCCTACGGGCACCCCTCTCCTTGTTAAGGTAGAGGGG	CRISPRCasFinder

spacers of NC_019678_34

>34.1|6795084|52|NC_019678|CRISPRCasFinder
AAATTGAAATTTTTTCTGTAAAATCCCTCTCCTTGATTAAGAAGAGAAGAAT

CRISPR arrays and Neighbor proteins around NC_019678_34

CRISPR arrays

The CRISPR arrays of NC_019678_34

>merge|NC_019678|34|6795034-6795185|CRISPRCasFinder
TAACCTCACCCCGCCCTACGGGCACCCCTCTCCTTGTTAAGGTAGAGGGGAAATTGAAATTTTTTCTGTAAAATCCCTCTCCTTGATTAAGAAGAGAAGAATTAACCTCACCCCGCCCTACGGGCACCCCTCTCCTTGTTAAGGGAGAGGGG

>NC_019678|34|31|6795034-6795185|CRISPRCasFinder
TAACCTCACCCCGCCCTACGGGCACCCCTCTCCTTGTTAAGGTAGAGGGG	AAATTGAAATTTTTTCTGTAAAATCCCTCTCCTTGATTAAGAAGAGAAGAAT
TAACCTCACCCCGCCCTACGGGCACCCCTCTCCTTGTTAAGGGAGAGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015121352.1|6803341_6803752_+|DUF1499-domain-containing-protein	unknown	unknown	gnl|CDD|377828
NC_019678.1|WP_015121345.1|6796693_6796882_+|DUF4089-domain-containing-protein	unknown	unknown	gnl|CDD|372560
NC_019678.1|WP_015121340.1|6790186_6790876_-|bifunctional-demethylmenaquinone-methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol-methylase-UbiE	unknown	unknown	gnl|CDD|234689
NC_019678.1|WP_015121350.1|6799802_6801263_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_019678.1|WP_015121338.1|6787374_6788094_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121347.1|6798557_6799007_-|YbjN-domain-containing-protein	unknown	unknown	gnl|CDD|371210
NC_019678.1|WP_083894154.1|6795274_6795583_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121337.1|6786669_6787173_-|DUF664-domain-containing-protein	unknown	unknown	gnl|CDD|225200
NC_019678.1|WP_044291202.1|6785747_6786596_-|dienelactone-hydrolase-family-protein	unknown	unknown	gnl|CDD|366780
NC_019678.1|WP_015121346.1|6796908_6798276_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-GatCAB-subunit-A	unknown	unknown	gnl|CDD|236409
NC_019678.1|WP_015121342.1|6792296_6793388_+|hypothetical-protein	unknown	unknown	gnl|CDD|375541
NC_019678.1|WP_015121343.1|6793503_6795033_+|AbgT-family-transporter	unknown	unknown	gnl|CDD|225525
NC_019678.1|WP_015121354.1|6804303_6804810_-|ATP-dependent-DNA-ligase-like-protein	unknown	unknown	gnl|CDD|185704
NC_019678.1|WP_157229470.1|6803784_6804255_-|hypothetical-protein	unknown	unknown	gnl|CDD|224706
NC_019678.1|WP_015121351.1|6801285_6802677_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_019678.1|WP_052330885.1|6783985_6784840_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|225117
NC_019678.1|WP_015121341.1|6790996_6791941_-|response-regulator	unknown	unknown	gnl|CDD|381113
NC_019678.1|WP_015121339.1|6788378_6789614_-|DUF445-domain-containing-protein	unknown	unknown	gnl|CDD|226834
NC_019678.1|WP_052330852.1|6805092_6805341_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121335.1|6785052_6785643_+|hypothetical-protein	unknown	unknown	gnl|CDD|235452

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015121352.1|6803341_6803752_+|DUF1499-domain-containing-protein	gnl|CDD|377828	pfam07386, DUF1499, Protein of unknown function (DUF1499). This family consists of several hypothetical bacterial and plant proteins of around 125 residues in length. The function of this family is unknown.	3.93213e-59
NC_019678.1|WP_015121345.1|6796693_6796882_+|DUF4089-domain-containing-protein	gnl|CDD|372560	pfam13318, DUF4089, Protein of unknown function (DUF4089). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 60 amino acids in length.	6.03573e-22
NC_019678.1|WP_015121340.1|6790186_6790876_-|bifunctional-demethylmenaquinone-methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol-methylase-UbiE	gnl|CDD|234689	PRK00216, ubiE, bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE.	1.63147e-117
NC_019678.1|WP_015121350.1|6799802_6801263_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.02422e-54
NC_019678.1|WP_015121342.1|6792296_6793388_+|hypothetical-protein	gnl|CDD|375541	pfam18087, RuBisCo_chap_C, Rubisco Assembly chaperone C-terminal domain. This is the C-terminal domain, also known as the beta domain, of Rubsico Assembly Chaperone protein (Raf1). Raf1 is necessary for rubisco to catalyze the rate-limiting step of carbon fixation through carboxylating the five-carbon sugar substrate ribulose-1,5-bisphosphate. The beta domains primary function is dimerization, which is critical for Raf1 to achieve the necessary avidity for complex formation with RbcL (the large complex sub-unbit of Rubsico) assembly intermediates. The beta domain is also involved, to a small extent, in binding to RbcL with use of the lustiness near the beta domain's conserved top surface.	2.49274e-73
NC_019678.1|WP_015121347.1|6798557_6799007_-|YbjN-domain-containing-protein	gnl|CDD|371210	pfam10722, YbjN, Putative bacterial sensory transduction regulator. YbjN is a putative sensory transduction regulator protein found in Proteobacteria. As it is a multi-copy suppressor of the coenzyme A-associated temperature sensitivity in temperature-sensitive mutant strains of Escherichia coli the suggestion is that it both helps CoA-A1 and possibly works as a general stabilizer for some other unstable proteins. This family was expanded to subsume other related families: DUF1790, DUF1821 and DUF2596.	5.30998e-11
NC_019678.1|WP_015121341.1|6790996_6791941_-|response-regulator	gnl|CDD|381113	cd17569, REC_HupR-like, phosphoacceptor receiver (REC) domain of hydrogen uptake protein regulator (HupR) and similar domains. This family is composed of mostly uncharacterized response regulators with similarity to the REC domains of response regulator components of two-component systems that regulates hydrogenase activity, including HupR and HoxA. HupR is part of the HupT/HupR system that controls the synthesis of the membrane-bound [NiFe]hydrogenase, HupSL, of the photosynthetic bacterium Rhodobacter capsulatus. It contains an N-terminal REC domain, a central sigma-54 interaction domain that lacks ATPase activity, and a C-terminal DNA-binding domain. Members of this family contain a REC domain and various output domains including the cyclase homology domain (CHD) and the c-di-GMP phosphodiesterase domains, HD-GYP and EAL. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	9.60714e-60
NC_019678.1|WP_015121337.1|6786669_6787173_-|DUF664-domain-containing-protein	gnl|CDD|225200	COG2318, DinB, Uncharacterized protein conserved in bacteria [Function unknown].	1.8905e-28
NC_019678.1|WP_044291202.1|6785747_6786596_-|dienelactone-hydrolase-family-protein	gnl|CDD|366780	pfam01738, DLH, Dienelactone hydrolase family.	6.28161e-80
NC_019678.1|WP_015121346.1|6796908_6798276_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-GatCAB-subunit-A	gnl|CDD|236409	PRK09201, PRK09201, AtzE family amidohydrolase.	0
NC_019678.1|WP_157229470.1|6803784_6804255_-|hypothetical-protein	gnl|CDD|224706	COG1793, CDC9, ATP-dependent DNA ligase [DNA replication, recombination, and repair].	1.52104e-08
NC_019678.1|WP_015121343.1|6793503_6795033_+|AbgT-family-transporter	gnl|CDD|225525	COG2978, AbgT, Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism].	0
NC_019678.1|WP_015121354.1|6804303_6804810_-|ATP-dependent-DNA-ligase-like-protein	gnl|CDD|185704	cd06846, Adenylation_DNA_ligase_like, Adenylation domain of proteins similar to ATP-dependent polynucleotide ligases. ATP-dependent polynucleotide ligases catalyze the phosphodiester bond formation of nicked nucleic acid substrates using ATP as a cofactor in a three step reaction mechanism. This family includes ATP-dependent DNA and RNA ligases. DNA ligases play a vital role in the diverse processes of DNA replication, recombination and repair. ATP-dependent DNA ligases have a highly modular architecture, consisting of a unique arrangement of two or more discrete domains, including a DNA-binding domain, an adenylation or nucleotidyltransferase (NTase) domain, and an oligonucleotide/oligosaccharide binding (OB)-fold domain. The adenylation domain binds ATP and contains many active site residues. Together with the C-terminal OB-fold domain, it comprises a catalytic core unit that is common to most members of the ATP-dependent DNA ligase family. The catalytic core contains six conserved sequence motifs (I, III, IIIa, IV, V and VI) that define this family of related nucleotidyltransferases including eukaryotic GRP-dependent mRNA-capping enzymes. The catalytic core contains both the active site as well as many DNA-binding residues. The RNA circularization protein from archaea and bacteria contains the minimal catalytic unit, the adenylation domain, but does not contain an OB-fold domain. This family also includes the m3G-cap binding domain of snurportin, a nuclear import adaptor that binds m3G-capped spliceosomal U small nucleoproteins (snRNPs), but doesn't have enzymatic activity.	0.00208913
NC_019678.1|WP_015121351.1|6801285_6802677_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.57486e-56
NC_019678.1|WP_052330885.1|6783985_6784840_+|helix-turn-helix-domain-containing-protein	gnl|CDD|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.91908e-29
NC_019678.1|WP_015121339.1|6788378_6789614_-|DUF445-domain-containing-protein	gnl|CDD|226834	COG4399, COG4399, Uncharacterized protein conserved in bacteria [Function unknown].	2.93847e-126
NC_019678.1|WP_015121335.1|6785052_6785643_+|hypothetical-protein	gnl|CDD|235452	PRK05419, PRK05419, protein-methionine-sulfoxide reductase heme-binding subunit MsrQ.	1.05832e-06

Protein sequences

>NC_019678.1|WP_015121343.1|6793503_6795033_+|AbgT-family-transporter
MTKRIRQSRRNLIDKSLAFIETVGNQLPDPITLFFILSIAVVIISAIASFLNVSVVNPSNDETIAAVSLLAPENIRKMFTEAVNNFTGFKPLGTVLVAMLGVGVAESTGLLSALLKQIVLIAPGRFICPVVVFAGVMGNIASDAGYVVLVPLGAVIFMAFRRHPLAGIAAAFAGVSGGYSANLIINPLDPLLAGLSQTAAQVIKPNYQVNATANYYFMIVSTFFITLIAWFVTEKIIEPRLGVYNQAEDIPMQTLTPSERTGLRWAGFSLLLLLAFIAALVLPPQGILRDPETFTIIPSPFIDSIVIIIALAFLIPGIVYGKFSGRIESDKDVANALGDSMASMGYYIALAFISAQFIAYFSWSNLGLILAVNGANFLKATGFTGVPLMLMFIIVSMLINLFVGSASAKWAIMAPIFIPMFMLVGYSPELTQAAYRIGDSSTNIITPLMPYFPVVVAFGQRYDKSLKIGTLISLMLPYSVAFLIGWAILFVIWFVLKLPLGPGAVSILS
>NC_019678.1|WP_015121342.1|6792296_6793388_+|hypothetical-protein
MTDLPPNSQNTENQPNQELAEELLRKLRQKEGSWVEWGQACAYLQKSGYNPQDIFEATGFEPIQQNQIIVGSQVYTSLEKGGASEEVKSHYSQRGSDLLYEFRMLAQEERAGAAELAFKHKVDADEVKEVARAIKDFSRLRNLPEGFSAHPGDAVAYQTWKQARQKSDLQLRSRFIAKGLKFAHTDAARKKIEQLLTDFTVVPQRPAPLLPFYRLESEAEMSRVVPVAGELPLTPDALKAVPIVEETEPFNMVKFSGEGAWVPLPGWQVVLNSEDPVVVLGKSDIFPNQEGNKPQPVMIAIDRSQRKWDNGSYFVVGNSGELDFQWFETEPDEVEILGRVIVIVKPKRIFDDEIIKDSWQIDE
>NC_019678.1|WP_015121341.1|6790996_6791941_-|response-regulator
MNNLPIDLDNIRNQIMTSQRRKKQKILVVDDEPDNLDLLYRTFRRDFQVLKADSGTNALQVLAEEGEVAVIISDQRMPEMKGTEFLSKTLPQFPDTVRIILTGFTDIEDLVDAINAGQVYRYITKPWDPEELKGVVQRAAETYDLLKQRTEELRRANSQMGLLTSSIQLVKAVSSKEESLAPIAAIYGETFAADGCILQLVENGSLTSTCGTFSQDGILDNWLDKDPLAQESIATSNMKVSVNVTKDERLKEVAHYSDTDTKSHLVVPVVHANEVTAVLSLQWKKPCTLREDELKLIHFSAQLLALVLNCAHYT
>NC_019678.1|WP_015121340.1|6790186_6790876_-|bifunctional-demethylmenaquinone-methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol-methylase-UbiE
MSEIRSIFNRIAPVYDQLNDWLSLGQHRIWKEMTVKWSAANTGDKVLDLCCGSGDLAFRLARRVGTNSEVQAVDFSPELLEVARERSKDYYPTPNISWIEADVLELPFDDNQFDAATMGYGLRNVTDIPRCLKELHRVLKTGATCAILDFNRPENTLMRGFQQWYLDNLVVPAATQMGLKEEYAYINPSLERFPSGREQLDIARKAGFAQTVHYPIANGMMGVLVVTKQ
>NC_019678.1|WP_015121339.1|6788378_6789614_-|DUF445-domain-containing-protein
MAFSNLLFYITPPLAGGIIGYFTNDLAIKMLFRPYRALYIGGKKLPFTPGLIPRNQERLARNVSKTIMQSLLTPEELQKLARRLLERERVEAGILWLLQMAIDQIKDDRDQKTTRILAGILKDLLGESLPRLLKVLARREDFLEAQIDQIFDQILLEFQLTDVQASRLADWLLQVVLPPDTIRLAIVDFLTDRTIQTIDESFRERTSGTYWVVANLFGLRNSLTRLRTYCLDEKDATNARIRELTQDLQLRDRIRRIVQNVSLQNLPIGTVRQLRKTTGDAVRQYIRTSGGDLLEGFSKTLDWDKIARLLLNRLSNSQVMNSSLEVVSKELALLLERYLERDLEQLVAQAIPILSIDQVIIDRIKSTSPADLENAIEGIVKNELQAIVTLGGILGFTVGLLQTCLLLISGR
>NC_019678.1|WP_015121338.1|6787374_6788094_+|hypothetical-protein
MNSKLTSLFVLPFLFATAVPAKAQSQLLDKNTALQTVAARILNDSQYRNVRMNCLSFVTVNATTSFFDFIVHEKHGNGCPSVANPKLIFERYRINRNNLRVEQFDKVANRWIAENKVQLKKANVPIFIGSLSQSPSAFNTFMQDNIGKTVYLEIVFGENIPQGYRSQQSMPFFEVSEKPRKQNSKFNTYFMQQAGNGYNWGKVTNYDEKNRKLSGFFKVGKPKQINDRWTSFDITFIPQ
>NC_019678.1|WP_015121337.1|6786669_6787173_-|DUF664-domain-containing-protein
MKLKQHFFTLTQYHHWAFKRLYEYLESVSEDDYRRECGLFFKSIHGTLNHSLLADKLWYGRCINQLFTVSGLDEELCSDRKQLETEIKNQTAKWSEFLQDTDADKLGSIIQYRTTQGSEKSLQLANILSHIVNHGTHHRGQVSAAITQFGYSAPEIDLPYFIAAQNQ
>NC_019678.1|WP_044291202.1|6785747_6786596_-|dienelactone-hydrolase-family-protein
MKKVTQNNFGRRELLIASLTAGFAMAVQPIYAQVIKTETSGLIAGAVKIPVADGEIPAYRAMPAKGGNFPVVLVVQEIFGVHEYIQDVCRRFAKLGYMAIAPQMFARYGDVSKLNNIQEIISKVVSKVPDTQVLSDLDATVVWADNSGKADVDKLGITGFCWGGRIVWLYAAHSPQLKAGVAWYGRLEESRTILQPQYPVDIAPLIKAPVLGLYGGEDTSIPISDVEKMRAALKQTKTATQIKVYPNQPHGFHADYRSSYNEEAAKDGWLLLQNWFKKYGAI
>NC_019678.1|WP_015121335.1|6785052_6785643_+|hypothetical-protein
MDSKFPLQEWRIVGFSALLVGTICAFVALIHGISEEGMRMAIRFTGRTSLIFFVSAFAASSLQKIWKTPLSIWMLKNRRYLGLSMAVSHSYHAIALVGLWFVTNGAAPQIEPLGTLGYVLLIALTITSFKIPAKWLGKRGWKILHKTAMHYLWLGLLFEYGLKLSKSDYIALPFLLLLILAMVLRFTAGRREKKLV
>NC_019678.1|WP_052330885.1|6783985_6784840_+|helix-turn-helix-domain-containing-protein
MAKDEPPVHLHLLESFDAQWQGLNLIYEIEPRNEMPEIDFGQHFIIIARGDFRASYMFNGSWHEVDYTKGDIAIIPANQGFPKTLIDREVPLLELFIDPTLINRNACELGNVDNIELVPQWHIRDPLIENIGLALKAELELNGAGSKFYAESMATALSIHLLSRYSSRQPQIKQYSDGLSNYKLREVTDYIQENLDKKLTQAELSAIICMSPHYFATLFKQSMGITPYQYVMKSRIEKAKQLLSKRDLTIVEICGEVGFQNKSHFTRVFRQHTKMTPKRFRDGV
>NC_019678.1|WP_083894154.1|6795274_6795583_-|hypothetical-protein
MAKADEVATQTTKLSSTKQKNPTESAQEIQKLLAPLKATYPTNSVYEKQVFVNKFREEIRKNFRVQELITDGGVELIKILCEPLDIPVEMGTKWLQTAQHYR
>NC_019678.1|WP_015121345.1|6796693_6796882_+|DUF4089-domain-containing-protein
MNDKKFNATEYINQTASLLNFNLPEEYRDGVVANFERIQVIAKLVNEFPLPEDIEAAPVFEP
>NC_019678.1|WP_015121346.1|6796908_6798276_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-GatCAB-subunit-A
MNLDSADAVSIATAVKQGQIKAVEVVKATLDRIAARDSQLNCFTKITAETALKDAALIDAEIAKGNNPGLLAGVPFAVKNLYDIAGLTTLAGSKINAENPPATQDATAVAKLKNAGAILVGALNMDEYAYGFVTENSHYGATHNPHDLNRVAGGSSGGSAASVAAGLVPLTLGSDTNGSIRVPAALCGIFGLKPTYGRLSRAGMVLFSSSFDHVGPFARSVRDIATTFDVLQGEDVETLNLTSHLTSVQNIDDFKIAIASNYFAQKAAPEALAAVQKVADALNISEYVSIPEAHRARAAAYIITASEGANLHLDKLKSRPQDFDFATRDRFIAGAFIPSSWYIQAQRFRNWYKEQVKEIFHKVDVIIAPTTPISAPEIGQETMILDGEEILVRPHLGLFTQPLSFIGLPVLSVPIQRKNALPLGVQIIAAPYNERAILRVAAVLEKMGVISADIV
>NC_019678.1|WP_015121347.1|6798557_6799007_-|YbjN-domain-containing-protein
MATVQNFDRSVIESYLTNRGLRFQRDDDGDFVVQFPYQEELGCEVILVFCAEGPQEDVYSVRLISNKRIPKEEWERVMSLCNDWNKEKRFPKAFLDIRITAEETLAIIVLEQHLHLKPGVHQDLFDDWTDIMVSGGFQFWMWVHKQHGL
>NC_019678.1|WP_015121350.1|6799802_6801263_-|serine/threonine-protein-kinase
MNKKIIGDRYEVINLLGKKPGYRTMLCNDMHTQQLVVVKFLIWDDDFEWQNLKLFEREAQILQSISHPEIPRYLDYFEVSKPHLKGFCLVQTYIKAASLEEHLQTGRTFGIEEVKQLAESVLKILIYLHSQQSQIIHRNIKPSNILLTNRSGNCTGDVYLVDFGSVKTLAAAKTATMTVVGTYGYMSPEHFGGKVIPSSDLYSLGATLIYLVTGIHPANLPQKNGRMRFAQLVNCPQGFSNWLKRMIEPVEELRFDSAEAALQGLQQTSNYSNNLFNNEHCNSSHNLINFKKPFGSKIFLKNKLNRLEVVFPRQRISALKYDLLFLFIKLCASVIILPPMLLTICIFFNNIFYGLAFTMSMNSVLFALILLLFNIAICGTCIAFLVNIIDSFVQVLIKLLKRENIKIEQQQLCLSFDWLCFKSCFLRSISLKNITKLEKKMIAGSNHQWDIVANFGTSQYKLFDNIDLTEVEVDWLCSELNEYLNR
>NC_019678.1|WP_015121351.1|6801285_6802677_-|serine/threonine-protein-kinase
MSLRVLKERYEILRQLAKKAGRKILLARDLQTNELVVIKLLIFNSEIEWEELKLFQREAQILRNLSFSAIPSYIDFFEVALSNKKALAFVQSYIEAVSLEQHIQNKGTFSEIEVKQLAKFLLQILIYLHGQNPSVVHRDIKPSNILLTNRSGNSIGDVFLIDFGSVQTLTSSESDICTVVGTYGYMSPEQFGARAVAASDLYSLGATLIYLLTGKSPVDSPQKLGKFEVWRINNCSRELGKWLKKMVEPELEKRFKSAAEALNSLDKLSSTNLSDFSSNLSKKISIKKSADVIEITTPCRKDRESSIVHFIGTLNVAILYGMSSILLLPKIEAIFQPIFINHGLMNNYLLAATAILMAMLSIYVTIWLKIIVNMLFIPFGKKKLQIDKQRIYFSYKLLGLEYRYRPSIPRQAIIKLDSNTNKIPEVIIWLGIYKYSFGKGFLNTAQAAWLSRELRDWLDIKTI
>NC_019678.1|WP_015121352.1|6803341_6803752_+|DUF1499-domain-containing-protein
MIFSGTRPDNLGVNNGKLAACPKSPNCVSSQSPSSDETHFIQPLKYTSTTEKALNDLKNVIQSEDRTKIINESSDYVYAEFKSALMGYVDDVEFYLDSTTNTIHVRSASRLGQSDLGVNRKRIETIRTKFNQIQGS
>NC_019678.1|WP_157229470.1|6803784_6804255_-|hypothetical-protein
MLERNRSSQCLRKDYFENLPTARSQEQKKELVLNQQSEGREGEVWILKNCVYTGGKDKHSQAMLRTKYCLELDLVVTDLTLVKGTGRPFSAAVVAREVAGKLVPVGSVGTGFSLQDMREIIRRHTETPGSVKITVRCLGLTENGNLWHGRFIGLCE
>NC_019678.1|WP_015121354.1|6804303_6804810_-|ATP-dependent-DNA-ligase-like-protein
MKPSTIPELPLHLQPGFVQTMQAVDAPQERSYYINSPEYWGQPKRDGSTLVVVATPDQVYYQSRSAKMKRQPCEEINQALQQAAINIGTFILDGELYYSSVIGSEHRTAAQAATINANQEVSTSPKPIYAIFKALWFAGNDLTIATETERIAAAEKITPFPVEDYLTN
>NC_019678.1|WP_052330852.1|6805092_6805341_+|hypothetical-protein
MKRQLVWLTKFFTNCDRNSYALLYRRAEAIYLGKQNLNNLRKSNESLQVKLRQFKQILALIVFGRQILWTRPGLRNRLKIKR

Crispr_ID: NC_019678_35

• CRISPR_ID: NC_019678_35
• CRISPR_location: 7032598-7032735
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 1 spacers

Consensus repeat of NC_019678_35

Consensus_repeat	Method
AAGGAGAGGGGTGCCCGGAAGGGCGGGGTGAGGTTTTCT	CRISPRCasFinder

spacers of NC_019678_35

>35.1|7032637|60|NC_019678|CRISPRCasFinder
TCTTCCCTTCTCCTCGATAAGGAGAGGGGTGTAGCAAGGTTTTCTTCCCTTCTCCTTGAT

CRISPR arrays and Neighbor proteins around NC_019678_35

CRISPR arrays

The CRISPR arrays of NC_019678_35

>merge|NC_019678|35|7032598-7032735|CRISPRCasFinder
AAGGAGAGGGGTGCCCGGAAGGGCGGGGTGAGGTTTTCTTCTTCCCTTCTCCTCGATAAGGAGAGGGGTGTAGCAAGGTTTTCTTCCCTTCTCCTTGATAAGGAGAGGGGTGCCCGGAAGGGCGGGGTGAGGTTTTCT

>NC_019678|35|32|7032598-7032735|CRISPRCasFinder
AAGGAGAGGGGTGCCCGGAAGGGCGGGGTGAGGTTTTCT	TCTTCCCTTCTCCTCGATAAGGAGAGGGGTGTAGCAAGGTTTTCTTCCCTTCTCCTTGAT
AAGGAGAGGGGTGCCCGGAAGGGCGGGGTGAGGTTTTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015121508.1|7020973_7021957_-|xanthine-dehydrogenase-family-protein-subunit-M	unknown	unknown	gnl|CDD|224238
NC_019678.1|WP_015121511.1|7025334_7025592_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121525.1|7044713_7045151_-|DoxX-family-protein	unknown	unknown	gnl|CDD|225168
NC_019678.1|WP_015121505.1|7016734_7017328_-|nucleotidyltransferase-family-protein	unknown	unknown	gnl|CDD|133025
NC_019678.1|WP_157229336.1|7038983_7039694_+|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl|CDD|366703
NC_019678.1|WP_015121519.1|7037955_7038522_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121517.1|7035167_7036016_-|RNA-ligase-family-protein	unknown	unknown	gnl|CDD|378183
NC_019678.1|WP_015121509.1|7022113_7022695_-|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	unknown	unknown	gnl|CDD|236910
NC_019678.1|WP_015121522.1|7042332_7042902_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121512.1|7025823_7027422_+|hypothetical-protein	unknown	unknown	gnl|CDD|375554
NC_019678.1|WP_015121523.1|7043106_7043679_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121506.1|7017414_7018524_-|XdhC-family-protein	unknown	unknown	gnl|CDD|379212
NC_019678.1|WP_015121514.1|7029959_7030523_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_019678.1|WP_015121507.1|7018721_7020863_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	unknown	unknown	gnl|CDD|224446
NC_019678.1|WP_015121521.1|7040671_7042231_+|D-alanyl-D-alanine-carboxypeptidase/D-alanyl-D-alanine-endopeptidase	unknown	unknown	gnl|CDD|224938
NC_019678.1|WP_015121518.1|7036439_7037663_+|amidohydrolase	unknown	unknown	gnl|CDD|349936
NC_019678.1|WP_015121516.1|7033969_7035088_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|226986
NC_019678.1|WP_015121513.1|7027789_7029520_+|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_019678.1|WP_044291219.1|7044286_7044721_-|DoxX-family-membrane-protein	unknown	unknown	unknown
NC_019678.1|WP_044291217.1|7023589_7024990_+|magnesium-transporter	unknown	unknown	gnl|CDD|129495

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015121508.1|7020973_7021957_-|xanthine-dehydrogenase-family-protein-subunit-M	gnl|CDD|224238	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion].	6.80612e-86
NC_019678.1|WP_015121509.1|7022113_7022695_-|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	gnl|CDD|236910	PRK11433, PRK11433, aldehyde oxidoreductase 2Fe-2S subunit; Provisional.	1.69615e-86
NC_019678.1|WP_015121525.1|7044713_7045151_-|DoxX-family-protein	gnl|CDD|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	2.8153e-14
NC_019678.1|WP_015121505.1|7016734_7017328_-|nucleotidyltransferase-family-protein	gnl|CDD|133025	cd04182, GT_2_like_f, GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	7.00622e-70
NC_019678.1|WP_157229336.1|7038983_7039694_+|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	7.36733e-10
NC_019678.1|WP_015121517.1|7035167_7036016_-|RNA-ligase-family-protein	gnl|CDD|378183	pfam09414, RNA_ligase, RNA ligase. This is a family of RNA ligases. The enzyme repairs RNA strand breaks in nicked DNA:RNA and RNA:RNA but not in DNA:DNA duplexes.	2.13253e-17
NC_019678.1|WP_015121512.1|7025823_7027422_+|hypothetical-protein	gnl|CDD|375554	pfam18105, PGM1_C, PGM1 C-terminal domain. This is the C-terminal domain found in PGM1 present in Streptomyces cirratus. PGM1 is a gene product that links precursor peptides together to form the antibiotic Pheganomycin.	6.38424e-08
NC_019678.1|WP_015121506.1|7017414_7018524_-|XdhC-family-protein	gnl|CDD|379212	pfam13478, XdhC_C, XdhC Rossmann domain. This entry is the rossmann domain found in the Xanthine dehydrogenase accessory protein.	3.67742e-46
NC_019678.1|WP_015121514.1|7029959_7030523_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.23754e-24
NC_019678.1|WP_015121507.1|7018721_7020863_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	gnl|CDD|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	0
NC_019678.1|WP_015121521.1|7040671_7042231_+|D-alanyl-D-alanine-carboxypeptidase/D-alanyl-D-alanine-endopeptidase	gnl|CDD|224938	COG2027, DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Cell envelope biogenesis, outer membrane].	5.98147e-113
NC_019678.1|WP_015121518.1|7036439_7037663_+|amidohydrolase	gnl|CDD|349936	cd08014, M20_Acy1-like, M20 Peptidase aminoacylase 1 subfamily. Peptidase M20 family, uncharacterized subfamily of uncharacterized bacterial proteins predicted as putative amidohydrolases. These are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. Aminoacylase 1 (ACY1) breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine).	0
NC_019678.1|WP_015121516.1|7033969_7035088_-|AAA-family-ATPase	gnl|CDD|226986	COG4639, COG4639, Predicted kinase [General function prediction only].	1.97e-27
NC_019678.1|WP_015121513.1|7027789_7029520_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.2022e-46
NC_019678.1|WP_044291217.1|7023589_7024990_+|magnesium-transporter	gnl|CDD|129495	TIGR00400, mgtE, Mg2+ transporter (mgtE). This family of prokaryotic proteins models a class of Mg++ transporter first described in Bacillus firmus. May form a homodimer. [Transport and binding proteins, Cations and iron carrying compounds].	6.93534e-171

Protein sequences

>NC_019678.1|WP_015121514.1|7029959_7030523_+|pentapeptide-repeat-containing-protein
MKSAIVASITLLACFGFMEQAKAFNPQDVERFKANGACPRCDLSGANLSQANLSKVNLRDANLRGADLTGTNLSNADLTGADLQNAVLIGANLSGASLMGANLRSASMENANLSFAALMSANLSAANLSGANVFLANFRGANFRLTTLRNGVVSSDKPYWWSLQSESLKDCNKFTSENARGTTCYNE
>NC_019678.1|WP_015121513.1|7027789_7029520_+|protein-kinase
MPNSQPNLNAIHCVNPNCSRPYPQPWGNKFCLACGSQLQLQDRFIPLERLGAGGFARIYTVWDVNTQTEKVLKVLVETSPKALELFAQEAEVLQRLKHGGVPKVEAGGYFFHNLSNSVQELDLPCLIMEKINGQTLEEVRYLYPQGCSEELVLDWLKQAVDILRHLHEHMIIHRDIKPSNLMLRNPASNLKNSQLVVIDFGGAKHFSVASSHRQSSSTRLFSTGYSPPEQVTGRNVGPTADFYALARTMIELLTGKNPQELEDIRTGTLRWRAALKFSEYGSDVNPLLVDLLDDMAQEEVRSRPENALIIQKRLSQIIKSTSYLPAHPRKGFFKGTKEFIQQFISGTTQGVSNTTLFAFNIITGIIRGSFETLWTIILACIGACIGTVAGFFLAFATALGDKVGEVVSNILIAFTSTPQPVLGSEIVLFAVSGLTTAWAITLAGGFNQRRRFLIASVMGIIGYSGGWFILQLIPPQQGEGWVGLILFSISLLTFGLGLRSHHIIHAIMTAFGTAIIFAGLINLGLSPTILNAATPFDISQLWIKLAFFCMLGSFTSFWLGVSTYLIVPALKILGWR
>NC_019678.1|WP_015121512.1|7025823_7027422_+|hypothetical-protein
MLHISDLEQLEKFRYLQSDLRDRWKCVEGDESDTSDVDILVIPSLSLDQRELKKVEGYEHYEERLLFALIRLWNPRNRLIYVTSVPLHPSIIDYYLQMLPGIPFSHARNRLLLLSTYDSSLKPLSQKILERPRLLQHIRHALRIDKSFMICYNSTGFEGQLSLKLGVPLYAAAPDLQIWGTKSGSRQIFAESEVPHPDGSELMWNISDLAEAGAKLWEREPSLKRMVIKLNEGISGEGNALLDLRPMLEFAPSKASHQERVTKITESFNNMSFQAKQETWSTFSGRIPELGAIVEAFVEGNIKLSPSVQGRITPTGEVEILSTHDQILGGPDGQIFLGCKFPADEDYRLQLQQLGLQIGLKLAEKGALERYGVDFIVVKQDGRWDIQAIEINLRKGGTTHPFMTLKLLTNGRYEPSTGLFYSQQGRPKYYIATDNLQKDRYRGLLPNDLMDIIAQHRLHFDTGTETGTVFHLMGCLSEFGKLGLTSIGDSPQQAEEIYNKVVKVLDEETPNSDDDFSSLSKQTFPISWEGFS
>NC_019678.1|WP_015121511.1|7025334_7025592_-|hypothetical-protein
MASPTPLKGTDLVDCAKANAKQGIETAALQCGYGDDLNKFRQELSDACSEMNLQVSELNELITTPDARLNINTGEVVAPDTPADL
>NC_019678.1|WP_044291217.1|7023589_7024990_+|magnesium-transporter
MTEMNNVASVIQESTRRELRDLVRTQLQMLLEQGDLRGAKAILVPVQPADTAEVIEGLPETMHALVFRLLSKNEAIEVYEYLDRSVQEKLIEEFRSQEVLDIVDKMSPDDRARLFDELPAKVVNRLLEQLSPTQRQATAQLLGYESGTAGRLMTPEFILLKENFTVAQALERIRRQANASEMIYYLYVTDNARHFTGIVSLRQLVTARTDQTIDEIINHDLIYVHTDTDQEEVARVIQKYDFLAVPVVDKEKRLVGIITVDDVIDIIQEETTEDIYALGGGVQSNGDNYFQTDLFTVARKRVVWLLVLLVTNTVTGTIIKSEEDILRKVVTLAAFIPLLTGTGGNVGAQSSTVVIRGMNTDEIRSLGTIQVIAREALAGAILGVTLGAIATLWAFLLQGNLQVAIAVGSSLVAISILASVSGSSLPFLFRFMKLDPALMSAPFITTAVDVAGVLIYFGLARLILNL
>NC_019678.1|WP_015121509.1|7022113_7022695_-|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein
MTTTKPNPLSTNAQSKSVDTVPVKLKINGTEHTLNIEPRVTLLDALRERLNLTGSKKGCNHGQCGACTVLINGERINSCLALAIMHEGDEITTIEGLADGDELHAMQTAFVNNDGFQCGYCTSGQICSAVALLSEIEAGQASTVTDLEEIANPTASIELTDTEIRERMSGNLCRCGAYPHIVAAVREAYQVKG
>NC_019678.1|WP_015121508.1|7020973_7021957_-|xanthine-dehydrogenase-family-protein-subunit-M
MKPFNYQKANSSNAAVQELSSNNQAKFIGGGTNLLDLMKSGVEVPDSLIDITKLPLADITELPNGGVRIGALARNTATANHPLIRERYSLLSQAFLSGATQQLRNMATVGGNLMQRTRCYYFYDTATPCNKREPGSGCPAVEGFNRIHAILGATDACIATHPSDMCVALAALDAVVRVVNASGEEREIPATEFHRLPGDTPNIDTNLQENELITAVDLPPSNSGAKSYYLKVRDRASYAFALVSVAAALEIENNSIKTARLAMGGVAHKPWRATNAEEILIGASPTEEVFRQAAETALQGAQGYQHNNFKIELAKRAIVRALTTLAE
>NC_019678.1|WP_015121507.1|7018721_7020863_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit
MVNTIGKPLNRVDGSLKVTGGAHYSAEFPQENLAYAVGIPSTIARGKIQSIDTSAAESLPGVIGIITHENAPKFEPLKSFMKGGTAAEEYSPLQDNAVYYSGEHIGIVIADSLEQATYAASLVQVTYDEETPIVEMQKHRNEEFEPQTVFGKEPTFIRGNPQDAFEKADIKVDEVYTTPTENHNPIEPSATIAVWENDKLTVYTSTQNNYGTKKALATSLQIPEENVRVICQFIGGAFGCKGAFWSHMLLPAIASRHVNRPVKLVLTRQDMFNVVGHRAETEQNVKLGAAKDGKLTAIVHDGVSHTSMYDDFVEPFTIASHMLYACENLQASQRLIRLNRVTPTFMRAPGEASGTFGIESAMDELAYALKIDPVELRLRNHADTDPAKNIPWSSKSLKECYQVGAEKFGWSKRNPEIGSMRDGRYLIGMGMATATYPVMVFPASAKAKMLSDGSVVVQSSTHEMGGGTATVMAQLIAETLGLPFDKVCFEYGDTRLPQAPVSGGSATVGSVGSAVHGVAKALQAKVLELAGKDKNESLTIEDYSQILKQNNLEQIEADYSFQPEQEQNYSKHSFGAQFVEVRIDPDFGEVRINRCTGAFACGKILNHKTARSQFMGGIIMGIGMALMEESVVDPNFGRVMNANLGEYHVPVNADIPDIDIEMVEEVDNHVNPIGTKGIGEIGITGAAAAVANAVYHATGKRIRSLPITPDKVM
>NC_019678.1|WP_015121506.1|7017414_7018524_-|XdhC-family-protein
MKELKNIISAIDDLEKIGETAIATLVKVSGSTYRSPGARMLINNNGNTIGAISGGCLESDVFEKSQAVIESKNPRVIKYDTTSEEDMIWGLGLGCQGIAYVLIEPLRENQLQEIAFIKKCLLSRSYGAIARVITVGGETETQVGQRLLLGEDTIINNLTDDNLLTEVLSDTKAALQNNSSILKEYSLKAGRIEVFIEVIQPPLSLIVFGAGYDVLPLVNFGKQLGWDVTVVDNRQREASKKRFEQADKIQLCGPEEILDNIEITERTVAVVMSHNYLDDLEMLKLLVPSDLNYLGILGPKKRTNRILKELQAEGIMQNANIHSPVGLDIGADNAEEIALSIVSEIKSVISQRNAGFLRNRNAPIHANKE
>NC_019678.1|WP_015121505.1|7016734_7017328_-|nucleotidyltransferase-family-protein
MKNVGLIILAAGKASRMGKPKQLLTYQGNNLISHAVKIGLNSICKPVLVVLGAYAEKIKPEIDKFPVQILENPVWETGMASSISAGIKAIKQSNHNLDAVIIGLTDQPLISEAVFNQLIQKYQETENKIIASAYDDVVGVPALFHQNLFVELMQLEGDKGAKALMRKYQDEVLAIEIPEAAIDIDTPDDYEKLLIGS
>NC_019678.1|WP_015121516.1|7033969_7035088_-|AAA-family-ATPase
MWTFPYCPNKGDFAINWRELENKFEWLRVLADCPQDARYHEEGDVLTHTKLVCEALIALPQWQALPEIQRSMLFAGALLHDVAKPKATKIEDSGAISSKGHVLQGAKMAQEILWDLNVPFQQREEIVSLVKYGSLPLWFWDKLNPQKAVIKASQIIRCDMLAMLAEADVRGRYCNDQNQLFERIDFFREFCRENNCFSQPRLFPSAHSRFIYFQKENGNPDYHAYDDTRFQVVIMSGLPGSGKDTWIQENLPEYKVISLDDLRREMGIKPGDNQGEVANAAKYLAKEYMRTGVSFVWNATNLNKQLRGMLIRLFAAYQADIRIVYLETSWSNLLKRNKTRTDKVPEKVLYRMKNRLEVPTIIEAHRVDWIAS
>NC_019678.1|WP_015121517.1|7035167_7036016_-|RNA-ligase-family-protein
MKQIYKYPRTHHIQGSRLQPGDEDLNDIPFAEIKQRYAVVEEKVDGANAAISFSADGQIQLQSRGHYLTGGAREKHFNLFKQWANTHVASFWEVLGSRYILYGEWLYAKHTVFYDALPHYFLEFDVLDLEKQVFLSTAKRKQLLAGLPIVSVPLLFAGEIQSYKQLISFLGKSYYQTSEHLQNFEKICLEKGLDVERSLQQTDRSSVIEGLYIKIESADTVINRYKYVRSSFLTTIQQSDGHWLNRPIIPNQLCDGVDLFSEQLSGSSRGGREGEGVEGVRK
>NC_019678.1|WP_015121518.1|7036439_7037663_+|amidohydrolase
MLSRIKDLAAELAPRLIEIRRHIHSHPELSGEEFQTAAFVAGVLSSNGIHVEENIGKTGAIGELEGNGSDKRILAIRTDMDALPIQELAPLDYASRNQGIMHACGHDVHTTVGLGTAIILSKLSQEIPGKVRFIFQPAEEIAQGASWMVADGAMENVESILGVHVFPSIPAGSVGIRYGALTAAADDLEITITGESGHGARPHQAIDAIWIAAQVITTLQQAISRTQNPLHPVVLSIGKITGGRAPNVIADSVLLQGTVRSLHPDSSKELPSWIENIVKNVCDTYGAKYKVDYRQGVPSVQNDLALTQILQTAAEEAWGSDRVEILPEPSLGGEDFSMYLEKAPGSMFRLGVGFADREVNHPLHHPKFEVDESAIITGVVTVAYAAYKYWGLKSDTVQNLTPVATNS
>NC_019678.1|WP_015121519.1|7037955_7038522_-|hypothetical-protein
MKYRDSSQRLDINCLLHQLINVDPTDSAPKKSEPDINCLLDELINLHPINLAQKKSGLDINRLLHTLQQIKRYCEFKPNCRLTQFEKRYLCLCLHGYSGREIAFIYDENRLPKKEELIQYKDKLDARIRNLQKEASKGLNKYLKLLLGLEESANKPRNGELIKILKEKGYGINSGQKKKTSFIRVNRE
>NC_019678.1|WP_157229336.1|7038983_7039694_+|peptidoglycan-DD-metalloendopeptidase-family-protein
MSPTFQAIGSASSSVNKNVQSDAQKSTETEPKANTGGSKSRFGISSKAMLVAHAPRSSRTIRASRTSKKRRSRAIRATNASKKRSRKIKVARASRRRLYWRLPWVGATATVTQRWHSDSWGRYKSVDFGLPAGTPVVAPIASRVLSFCNAGRNHLAIRLQAADGNRYSLVHVKSRSVYVNKRYRKGQIIGVIARNTPRNRCARSTGPHLHMSFPRQNFKLGRYWFSRSYIPKRLKP
>NC_019678.1|WP_015121521.1|7040671_7042231_+|D-alanyl-D-alanine-carboxypeptidase/D-alanyl-D-alanine-endopeptidase
MSKKSSLSLLLLFFGVQFGVNQQAATAQTNSGVVIPTTPRNTPRVPSRTIPTLPRRTPTTPRRTPAPSGNRFCASQLNYAVDSITNRTQFNRTHWGIMVQNLGSPRTLYSRNHKKYFTPASVTKLMTTAAALQTLSPNYRIRTSVYETGNGVVQVVGRGDPSLKSEQLEVLAKQLRQKGVRRINRLIANDAYFKGEAVEPSWMWEDVQFYYGAPVNSLMLNENAAVIRLYPQRVGRRLLLKWDNPLDASGWKVVNQTMTARKGTKRYIEVKRDLKGQTLYLTGQLPEGSRPDITAIAVFNPIQNFLTHFRQSLRKQGVSVKGAYWGTTKTSGRELAAVQSPPLSELITETNINSNNLYAEALLKALATKKPLERNQTTVDAGLEVMKSTLTRIGVEPTTYKLVDGSGLSRKDLISPQALVQTLQGMAKSRYASVFRASLPVAGKNGTLKYRFKDIAPEGLVQAKTGTMTGVVTLAGYVNAPNYGPVAFSIMVNQTEQPIRTVRNAIDEIVVHLSKMQRC
>NC_019678.1|WP_015121522.1|7042332_7042902_-|hypothetical-protein
MKVLSKVLLITLLAAIFGLTGCNQSKFSEVNKSVIPLPAIKSYTAENSARVVFPQKANVRLIGGASKIGWVNINLQTKQIEVTLNNNSETFDFNRIKKVNFDLNRAIFSDGDILIKGEKLSDFIRESLIRVPMSDLKLENEAGEVTVKLNNSESSQNYVVRDGIYVVQDILFDESLDRTTLKVLCCMAE
>NC_019678.1|WP_015121523.1|7043106_7043679_-|hypothetical-protein
MKLVPKVFLITLVASVVGIVGYNQILLSKDTELPKSSLKIEQVPIDDSIILLLPQVIIELKEGKPKYGWLTQFNSPKKELQITWNGNYQKINFKDIKKLKFVIGKAPFSSPDILVRNEKELSEVKQETWLAVPTKDFKLQANRVDEAKLKLTNSILASSEQLILNSKYVIETIEFDESLQKMKMKVFLNI
>NC_019678.1|WP_044291219.1|7044286_7044721_-|DoxX-family-membrane-protein
MYNPKVQLRNSDIVLAYTFLRLVFGINMFVHGLVRLPNISGFVDSQVGLYKDIAIPPLLIAGPAYLIPIVEFAVGLLLILGLQTRKALIANFLLMMTLMFGVCLLQKWDIAGSQLIYNLILFILLAGCNFNLISVDSWLSRRKG
>NC_019678.1|WP_015121525.1|7044713_7045151_-|DoxX-family-protein
MGFKKYIPLIGRAFLAAIFLKAAVANTLGFQGIVEMMTNRGLPAPQLLLLGNIFCTLVGGLSILLGFKARIGAILLIIFLVPTTFVFHNPFTDPKELNAFLKNFGLVGSMLLIYYYGTGPVSLDAESATNDYDDTYVTDSDRANV

Crispr_ID: NC_019678_36

• CRISPR_ID: NC_019678_36
• CRISPR_location: 7084754-7084859
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 1 spacers

Consensus repeat of NC_019678_36

Consensus_repeat	Method
GGAAATCGTCCTCAAGAAATAGCTCAAG	CRISPRCasFinder

spacers of NC_019678_36

>36.1|7084782|50|NC_019678|CRISPRCasFinder
TAAAAGCACAATTAGAAGAAGCACAAGCGAATTTAAGTAAATTAATTGCT

CRISPR arrays and Neighbor proteins around NC_019678_36

CRISPR arrays

The CRISPR arrays of NC_019678_36

>merge|NC_019678|36|7084754-7084859|CRISPRCasFinder
GGAAATCGTCCTCAAGAAATAGCTCAAGTAAAAGCACAATTAGAAGAAGCACAAGCGAATTTAAGTAAATTAATTGCTGGAAATCGTCCTCAAGAAATCGCTCAAG

>NC_019678|36|33|7084754-7084859|CRISPRCasFinder
GGAAATCGTCCTCAAGAAATAGCTCAAG	TAAAAGCACAATTAGAAGAAGCACAAGCGAATTTAAGTAAATTAATTGCT
GGAAATCGTCCTCAAGAAATCGCTCAAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015121569.1|7096665_7097568_-|DUF928-domain-containing-protein	unknown	unknown	gnl|CDD|368720
NC_019678.1|WP_015121560.1|7085935_7087201_+|FtsX-like-permease-family-protein	unknown	unknown	gnl|CDD|182528
NC_019678.1|WP_015121557.1|7082128_7083403_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NC_019678.1|WP_044291224.1|7087223_7087886_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NC_019678.1|WP_015121555.1|7080955_7081228_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121552.1|7078365_7079106_-|TVP38/TMEM64-family-protein	unknown	unknown	gnl|CDD|223475
NC_019678.1|WP_015121562.1|7087891_7088404_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NC_019678.1|WP_015121549.1|7072607_7073645_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121563.1|7088480_7089974_+|phytoene-desaturase	unknown	unknown	gnl|CDD|274273
NC_019678.1|WP_015121554.1|7080102_7080867_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|275103
NC_019678.1|WP_015121568.1|7095464_7096502_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121564.1|7090212_7091109_-|glycine/betaine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270331
NC_019678.1|WP_015121556.1|7081472_7082129_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_019678.1|WP_015121565.1|7091395_7092031_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224095
NC_019678.1|WP_015121566.1|7092146_7092893_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213262
NC_019678.1|WP_015121553.1|7079280_7079985_-|TVP38/TMEM64-family-protein	unknown	unknown	gnl|CDD|223475
NC_019678.1|WP_015121558.1|7083662_7084109_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121567.1|7093950_7095360_+|DUF1929-domain-containing-protein	unknown	unknown	gnl|CDD|199882
NC_019678.1|WP_015121550.1|7074234_7076361_+|hypothetical-protein	unknown	unknown	gnl|CDD|368963
NC_019678.1|WP_044292416.1|7076755_7078300_-|mercuric-reductase	unknown	unknown	gnl|CDD|235787

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015121560.1|7085935_7087201_+|FtsX-like-permease-family-protein	gnl|CDD|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	6.95505e-75
NC_019678.1|WP_015121557.1|7082128_7083403_-|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	3.19929e-57
NC_019678.1|WP_044291224.1|7087223_7087886_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	5.88702e-113
NC_019678.1|WP_044292416.1|7076755_7078300_-|mercuric-reductase	gnl|CDD|235787	PRK06370, PRK06370, FAD-containing oxidoreductase.	0
NC_019678.1|WP_015121552.1|7078365_7079106_-|TVP38/TMEM64-family-protein	gnl|CDD|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	3.05873e-43
NC_019678.1|WP_015121562.1|7087891_7088404_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.63817e-11
NC_019678.1|WP_015121554.1|7080102_7080867_-|glycosyltransferase-family-2-protein	gnl|CDD|275103	TIGR04283, glycosyl_transferase_family_2, transferase 2, rSAM/selenodomain-associated. This enzyme may transfer a nucleotide, or it sugar moiety, as part of a biosynthetic pathway. Other proposed members of the pathway include another transferase (TIGR04282), a phosphoesterase, and a radical SAM enzyme (TIGR04167) whose C-terminal domain (pfam12345) frequently contains a selenocysteine. [Unknown function, Enzymes of unknown specificity].	3.45257e-114
NC_019678.1|WP_015121563.1|7088480_7089974_+|phytoene-desaturase	gnl|CDD|274273	TIGR02734, Phytoene_desaturase_lycopene-forming, phytoene desaturase. Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	5.08531e-130
NC_019678.1|WP_015121569.1|7096665_7097568_-|DUF928-domain-containing-protein	gnl|CDD|368720	pfam06051, DUF928, Domain of Unknown Function (DUF928). Family of uncharacterized bacterial protein.	1.06032e-57
NC_019678.1|WP_015121564.1|7090212_7091109_-|glycine/betaine-ABC-transporter-substrate-binding-protein	gnl|CDD|270331	cd13613, PBP2_Opu_like_2, Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 periplasmic-binding protein fold. This group includes the periplasmic substrate-binding component of a putative ABC transport system that is predicted to be involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. The relative substrate preference of this group is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.02723e-139
NC_019678.1|WP_015121556.1|7081472_7082129_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.82066e-82
NC_019678.1|WP_015121565.1|7091395_7092031_-|ABC-transporter-permease	gnl|CDD|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	3.97903e-70
NC_019678.1|WP_015121566.1|7092146_7092893_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213262	cd03295, ABC_OpuCA_Osmoprotection, ATP-binding cassette domain of the osmoprotectant transporter. OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	1.91907e-139
NC_019678.1|WP_015121553.1|7079280_7079985_-|TVP38/TMEM64-family-protein	gnl|CDD|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	2.42437e-44
NC_019678.1|WP_015121550.1|7074234_7076361_+|hypothetical-protein	gnl|CDD|368963	pfam06537, DHOR, Di-haem oxidoreductase, putative peroxidase. DHOR is a family of di-haem oxidoredictases. It carries the two characteristic Cys-X-Y-Cys-His haem-binding motifs. The C-terminal high-potential site functions as an electron transfer centre, and the N-terminal low-potential site corresponds to the peroxidatic centre. Its probable function is as a peroxidase.	0.000591285
NC_019678.1|WP_015121567.1|7093950_7095360_+|DUF1929-domain-containing-protein	gnl|CDD|199882	cd02851, E_set_GO_C, C-terminal Early set domain associated with the catalytic domain of galactose oxidase. E or "early" set domains are associated with the catalytic domain of galactose oxidase at the C-terminal end. Galactose oxidase is an extracellular monomeric enzyme which catalyzes the stereospecific oxidation of a broad range of primary alcohol substrates and possesses a unique mononuclear copper site essential for catalyzing a two-electron transfer reaction during the oxidation of primary alcohols to corresponding aldehydes. The second redox active center necessary for the reaction was found to be situated at a tyrosine residue. The C-terminal domain of galactose oxidase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others.	2.07153e-31

Protein sequences

>NC_019678.1|WP_015121558.1|7083662_7084109_+|hypothetical-protein
MKAQLISALIATTIIGATASISNAQIPSAPRVNIQMENGVPSIPGIEFSDEQKEKLKEVNQEARSRMSEILTSEQQDDLRAAVDAGTNPQEAIKTLNLSNKQKNNLEKVQKWQRKQVLGILDNEQKRKIMQMRQRQGRQVGSYRLNIR
>NC_019678.1|WP_015121557.1|7082128_7083403_-|sensor-histidine-kinase
MIKLINFPSFHQLKNLKILQNHPFPLFAYLEWILLSICLLMEFRLGGLSKPGFIRESLNSPLVFFALIMFGIMGLKLPQTKTLYKIIYTLFGLFLMFLANYGLGKGIGFTPHLLLILVIRSCLVFDIKGRILIAALSWAFFIFTLNTNAPFKLPNKLRIENPEELTNIVFNLKITAGVLFTFILLFVMLLVNTVISERQSKQKLVLAHEQLRQYALRIENQATLQERSRIAREIHDSIGHSLTAQSIQLENALLFIDSNIEKAKSFLLQGKNMGANALKEVRFSVSALRSDPLKGKSLEFAIEDLFEEFKLKFQIKPKFYLPVNPILSPEINLTIYRIIQEALTNISKHSDADLVNIEIKTIDNSLYLSIQDNGVGFNPKQNTTGFGLQSMRDRAHALAGKFYLNSKPGEGCSIMMFLPFSGLD
>NC_019678.1|WP_015121556.1|7081472_7082129_-|response-regulator-transcription-factor
MVRLLLVDDQEIIRQGIKSLLESQPDFEVVGEAENGKQAISQVEALHPDMVLMDVRMPIMDGIAATKAIIQQFSQVKILILTTFDDDEYISQGMQFGAKGYLLKDTPLEPLANAIRLVHAGHTHLGPGLFEKIITSTPEIVTKKKTNPPQELEELTPREKEVLHLISSGASNKEIAQQLFISERTVKNHVTSILTRLNLRDRTQAAIFANSFSQFLNN
>NC_019678.1|WP_015121555.1|7080955_7081228_-|hypothetical-protein
MKAHAGGLCFSSPTIARLLAERVRKDMGDLAQPHTELELRYFTKSIANNNSTFLVLPLKTDKGIFGIELGNTIPIFVIFFNFVWGITTAW
>NC_019678.1|WP_015121554.1|7080102_7080867_-|glycosyltransferase-family-2-protein
MIYKQTALQEKKCLLSVNGSQTIATAKISVIIPTLNESKNLKATLVSTQTSTNVEVIVVDGGSDDNTVDIAESLGVKVISGYKNRASQMNAGAKNAKGDILLFLHADTLLPANFDGMIRTAMQQPSTVAGAFALRINAANIGLRLVEWGVKWRSRLFKMPYGDQAIFITKDKFNYIGGFPELPIMEDFELIRQLQKTGNITLIPVSVITSPRRWLKKGILQTTLINQIVIIAYFLGVSPARIRRWYRGEKLIKH
>NC_019678.1|WP_015121553.1|7079280_7079985_-|TVP38/TMEM64-family-protein
MKNQYKRFLKPVSIGCLIAFLIIVGNHFNLQGHFHQSLLWVDSLGWLAPVAFIVIYNIATLLFIPGSLLTLKGGCLFGLLWGSIYVLIAATIGATFAFLVGRYISRDWVCKQIGNKPKFKAIDKAVAKNGFKIVFLTRLSPIFPFNLLNYAFGVTQVSLKDYILGSIGMIPGTVMYVYMGSIIGHIAINNPSIPKSQEAQYIQLLLQGFGFIATIFVTIYVAKVAKKALKESMN
>NC_019678.1|WP_015121552.1|7078365_7079106_-|TVP38/TMEM64-family-protein
MNKFSRLSLFAVATFGIVILLNTNPALAQETASNAQGFNPQLWLKNALEWINEQGTVGGIAFMLLYIVATVAFLPGSILTLGAGVVFGVFLGSVYVFIGATIGAIAAFLVGRYIARGWVSKKIAGNEKFAAVDDAVGREGLKIVLLTRLSPVFPFNLLNYAYGVTGVSLKDYILGTIGILPGTIMYVYLGSLAGNIATIGTGDQPSNPTVVWAIRIIGFIATVAVTLYVTKVARKALNESTSIGEQ
>NC_019678.1|WP_044292416.1|7076755_7078300_-|mercuric-reductase
MSNSAFERVVIPPMDEHNQRLIANLHPNDWKNPEPVDCYDLVVIGAGAGGLVTSAGAAGLNVGLKVALIEKHLMGGDCTNVGCVPSKSLIRSARVVGEMWNAKEYGVVVPQEVEVDFPAVMERMRRIRADISPIDSVERFSNIGMDVFLGTASFISGDTIEVAGKKLKFKKAVIATGARATQLDIPGMKEAGYLTNETVFSLTQLPRRLAIIGGGPIGCELAQSFNRFGSEVTILHRGSHILNKEDSDAAEIVQKVFQKEKVGLILSSQIERVESTSEGKKIYYTSNGTKGSIVVDEILVGAGRTPNVEGLNLETVGVEYDSKGVTVNDNLVTTNPKIFAVGDICLSQKFTHMADATARIVIQNALFAPFGLGRKKLSDLVIPWVTFTDPEIAHVGMYENEAREKGLEVNTIKIDYEDVDRAITDGETEGFVKVHLKQGTDQILGATIVSSHAGESISEVTTAIVNGIGMNKLSGVIHPYPTQAEGIKKAADAYKRTKLTDGTRKLLGFLNKFS
>NC_019678.1|WP_015121550.1|7074234_7076361_+|hypothetical-protein
MASYKVNLKKNVFRGLYAKKARIFLLITVFIMAFAGILLSNCLMGTQPAFATFPKNRFRLLQPAPTLPVGYYDYFGQLLSPRRAARLVRKEGLDARDPISYQKVGAVEITQELIDKGEDIFLNRKIGDDFGLQSVFGFAQGFSTIVPEIRTAIGQLGGKPTNNLQITLEKDITLGSRTFPSGTAVNTGLKVERGGSLPLGFIPDSQTGAIGITCAACHAILSDEGERLLGVPNGQLNIPLLIALSPNTAAGFARLNFDPLDPQYQGNGKTIIDSKGQSVELPDPVLLETAFDDAVLDVPSGHFESSPDGINNTTQIPSLFTFKNNPYLADGQFAVGPFAGLSAVNNAVHSSEINLLAAAQLSEETLGIDPEVYIGTFLQNALDPRLRLPDGVKPSEWLRQKQQELGVLFAELEDQIPAPGAGDYPNLRPSLVTYNGLIFSPNSENPNDIASGKFFFANNAMSAFQNSLVPPANRTKENWQALRRGSVQRGARVFRKANCATCHIPPFFTDNQIHPINEIGTNSARAKSRLELNDLLVEPKLYSFDTPVPIPAGAEVLDVPTEGVSDTPTTLPKGILPDGGYKTTSLRGLYLSAPYLHDGGVAVRQGSLEVTRNGRFRVVDPSGLGLTGTLSQGLPADAASSLRALLDRELREQVIQANKANPALDPERSNLDGTGHEFYVDREAGFNYRQQKDLINFLLALDDNPGRF
>NC_019678.1|WP_015121549.1|7072607_7073645_+|hypothetical-protein
MNSYILTSKQTWLSKKYILIFVSVFMICNLLFTLLVFFQNGITTDKQTDIRHWVYSTKTELVKSISQEKLLVISGSNSAFGISCDMIANNIKVPCINGGTTATLGIDYILYNARSWAKKGDVVLLPLEYVHYSHSGIPNQELIRYTFAYDFNYFKQANLMKKIRMLYGLPFGYLIDNYIFKFKGKEYQNSQKVEKDIIYKVYGQLNQYGDVTDNTKANMTPKMLKKVEALEPLKFKNQEFGNPGTESIIRFIKWCKSKNVKVIATWPNTIWFETYNRKEEQEYLQKIDKLYDQLQVPVIGKPRDFMYDKSLFYDSAYHLNARGVLQRTQQLIDILEPYLKEIKSS
>NC_019678.1|WP_015121560.1|7085935_7087201_+|FtsX-like-permease-family-protein
MPSINHKNKYSISTIEILSIALESLWSNKLRTGLTMLGMIIGIASVIGITSVGQGVQKSTEEQIKSLGSDVLQVLAGEAKGGNISQGQGSSSTLTWEDAKSIANQVTAADAVSAYLQSRVQVVYEDENASTTVYGSDLDFPETRNTFPETGRYFNQAELDESQQVVVLAPTVKNKLFPEYINPVGEKIRIQGEIYQVVGVMEKKGSQGPMDRDDAVYIPLTTMSARIVGNNSLFGISINGIYVKYASEEQSSAAEFQITNLLRSRHNIQSPEDDDFRVTNQADILETLATVTGLLTTMIGAIAGISLVVGGIGIANIMLVSVVERTREIGIRKALGATDSAILNQFLVEAVVISTVGGVIGIVTGTAIAFIISTLAQFPFIISPTSVIIAFTLSTGVGLLAGVIPARNASKLDPITALRSD
>NC_019678.1|WP_044291224.1|7087223_7087886_+|ABC-transporter-ATP-binding-protein
MILMESITKHYLLGEVKVPILKGINLTIVKGEYLAIMGASGSGKSTLMNIMGCLDRASSGSYTLEGRKLTSFNNDELAYTRNQRIGFVFQQFNLLPRATALENVMLPMVYASTSKPERLQRAEAALIKVGLADRINNRPNQLSGGQQQRVAIARALVNNPAIILADEPTGALDTQTSHEVMDLFAELNAQGITIIIVTHEHDIAEITQRIIRVQDGLIIS
>NC_019678.1|WP_015121562.1|7087891_7088404_-|MarR-family-transcriptional-regulator
MDLQLINLIGAAAIAISDSIQNAAKEATGNTASFPAALVIVERYPTITVDLLAQYLQLSQSGAARLVERLVNQNLVERHQGNDRRFVHLRLTYDGKAMVEEIQQAKIAAVSNLLKPLTTQEQEQLLSTLSKMAGQYSNTEVLEEYICRFCDMDNCPLATCQERLEAWGKS
>NC_019678.1|WP_015121563.1|7088480_7089974_+|phytoene-desaturase
MAKNIIVVGAGPGGLATALRLKGQGYNVEIFESSNRVGGRMRGFQDGDYAFDTGPTILQLPNLYDDLFASAGLKREDYITFTRLEPYTKLRFWDDSTLELTTDFEKLKQQLQTFRDDLPAAFDRWYAREAKKYEAGYEPYLSQPARPILGYMRLDELGTGLRFRPWETLYQHFWNAFQDERLVYSLSYPAKYLGMHPTLSASVFSLIPYIEMAFGVWHPQGGFRALAQAIAQGFQDLGGKIHLNAPVKQAWLENRQVQGVELENGERIKADTVVVNADFARAVQTLIPQTAQGKYTDNFFAKKQFSCSTFMLYLGINRRYDDLPHHQLYLSEHIRKREKPFVDDSALDEIDPPFYVCNPTPVDSSNAPAGHSTLYVLVPIPHTGYGVDWHKKAKSYRDLIISRLPLLGFDEVEKHIVSETCYTADNWLNDYSVYLGAVFNLSHNWLQLGPFRPPIRSEYIDKLYWVGGAVHPGSGLMTILESAKNTARFVEEDLLKK
>NC_019678.1|WP_015121564.1|7090212_7091109_-|glycine/betaine-ABC-transporter-substrate-binding-protein
MKKFLTLFVICLCLSLGIASCNVTSVGSNGSDIIVASKGFTEQDILAELLAQQIEATSDLKVDRRTLQGTKLCHEALVAGNIDSYIEYTGTALTAVLKESVIDDPRKVYNLVKQAYEKQFNLEVAQPLGFENTYAVIVRGEDAKKYNIETISEAAKYASDWDIGIGYEFAEREDGLPGLIKAYNLQFQRRPKSMDLGLIYRALTQELVDVVVNNSTDGQIARLGLVILKDDKKYFPPYEAAPIVRKETLKKYPQLEKPLSQLAGILTADQMQELNYQVEGELRKIKEVVSEFRQAKGL
>NC_019678.1|WP_015121565.1|7091395_7092031_-|ABC-transporter-permease
MSDFFLIKYGSEIIERSIEHLVLVIIAIGIATVIGIPLGVLITRNKTLRQPILGIANILQTIPSLALLGLLIPVPIIGGIGPVPAIFSLILYAFLPIIRNTYTGIMNVNPAIREAGRGMGMTDRELLFQVEIPLALGVILAGVRVAIVIGIGIATIAAAIGAGGLGVFIFRGIALVNNQLILAGAVPAAFMALIADLGIGALERALTKGKS
>NC_019678.1|WP_015121566.1|7092146_7092893_-|ATP-binding-cassette-domain-containing-protein
MSQKNEYAVEFRNVTLSISQQKLVSNLNFQIRKGEALILLGRSGSGKSTTMKLINRLYRPTEGQVVFDDKSTTEWDEIKLRRKIGYVIQETGLFPHFTIERNVGLVPSLEGWNSKQIKSRVFELLKLVGLEPGQFASRYPHELSGGQRQRVGVARALAADPPVLLMDEPFGALDPITRLELQQEFKRLQQELGKTVVFVTHDIQEAFVLATRIGLMYGGELVFLGTTEEFKTTSHPEAVAFLKCLETV
>NC_019678.1|WP_015121567.1|7093950_7095360_+|DUF1929-domain-containing-protein
MPWEVSSTCPINPVHAALLRTGKVLFFTGSGNNPNDIPNADKGSALFDVQNGTFTRPEIPRNSNGTPIDIFCAGQAFRPAGNLLVAGGTLRYDPFFGEVASFFFSPTSEKWSKRQSMNGGRWYPTLVSLGNGQTLALSGLNETGNLNRFPELYSYSKGWRIFTSETSPFEQYAHVYLLDNGKLFYSGAQLGGNRGVSPRIITLPKNFSDTIGEQPVGGLQDSGKGNQAASVLLPPAQDQRVMIAGGGGGGTTARVNIVDLKSSNPSYQPAASLNNARMHHNAVILPNRTVFVCNGSGGNEDIGKSDLPAEIYDQATDTWTEVEDPSINGRVYHSVALLLPDGRVLTAGGNPFRGSVEFRIEIYSPDYIAANRPVINQAPSKASWGSSFTIETPQAGDIKWVNLVRPMATTHGLENEQRLVDVPINSSTGNSLTVDLTSNRNLAPPGWYMLTIVDNNNVPSVAKWVKVKK
>NC_019678.1|WP_015121568.1|7095464_7096502_+|hypothetical-protein
MELISRRRFGQIAIASGATVAIGSLLGKTFAQSPGVVILGITSGTVSSDSANGIDTDDVAESEAAEDSVIENDNNPKKPVVVKSFNVSNGQTKTVTTTQPILERGEFVSGFAVSEAGTLIVATANIAAEKSASNRLITVKGNSVETKEVSGVAKDESLDLIKLPDGSIAGIVKNENGTGSRKIVDVEAESGAVRKRTAPTKIPSRGRLESSNTISAQEPQANRSVAEAEELEAEKIPTLELPTELPSDKEYKNVVVCNDGNSYAFLTDFQGDTSLVNITTGKTIPVTFEGKVWNNGFSGFICAKNNQLYALGGRRYETPKFLHLLDKETGNLKRLAPFDVATITL
>NC_019678.1|WP_015121569.1|7096665_7097568_-|DUF928-domain-containing-protein
MLKSQYYQLFKLSFTINLILVISSLPVKAEKIDSSTNRQQNNASQVNRKKPESTRNLNVPRRHQQTFGNSKPRKSFLYFRQPQRQGTPQGTTPAGSRNGCYVAEKTPLSALVPVTKQTDGRVLRWGLTTKANPIFWFYVPYKLSSISNAKFSLRSRQNKTIYEKKIQFTNTPGVIGIPIEADLATLKVGEWYQYYLFMDIDCSYNEKSRKEFARAWVKREAIASGFEQQLKRLSPRQRGLFYAKHGIWYDAMVTFAQMKYLTRKNIEWNQMLELIGLEQISQVPLSNCCQDSPAENKSPS

Crispr_ID: NC_019678_37

• CRISPR_ID: NC_019678_37
• CRISPR_location: 7334255-7334348
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 1 spacers

Consensus repeat of NC_019678_37

Consensus_repeat	Method
AATGGTGCGTTACGGCATTTTTTA	CRISPRCasFinder

spacers of NC_019678_37

>37.1|7334279|46|NC_019678|CRISPRCasFinder
GTACTTTTTATAGATTATTTTATATTTTGAGTTTTATTTTTACGTT

CRISPR arrays and Neighbor proteins around NC_019678_37

CRISPR arrays

The CRISPR arrays of NC_019678_37

>merge|NC_019678|37|7334255-7334348|CRISPRCasFinder
AATGGTGCGTTACGGCATTTTTTAGTACTTTTTATAGATTATTTTATATTTTGAGTTTTATTTTTACGTTAATGGTGCGTTACGGCATTTTCTA

>NC_019678|37|34|7334255-7334348|CRISPRCasFinder
AATGGTGCGTTACGGCATTTTTTA	GTACTTTTTATAGATTATTTTATATTTTGAGTTTTATTTTTACGTT
AATGGTGCGTTACGGCATTTTCTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_083894156.1|7316487_7317414_+|site-specific-DNA-methyltransferase	unknown	unknown	gnl|CDD|334588
NC_019678.1|WP_015121730.1|7335229_7335742_-|Holliday-junction-resolvase-RuvX	unknown	unknown	gnl|CDD|234639
NC_019678.1|WP_015121727.1|7330010_7330532_+|hypothetical-protein	unknown	unknown	gnl|CDD|372967
NC_019678.1|WP_015121720.1|7317816_7318791_+|lysophospholipase-L1-like-esterase	unknown	unknown	gnl|CDD|238866
NC_019678.1|WP_157229342.1|7327576_7328083_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121726.1|7328520_7329900_+|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_019678.1|WP_015121738.1|7348266_7349436_-|cysteine-desulfurase	unknown	unknown	gnl|CDD|224029
NC_019678.1|WP_015121722.1|7323057_7325214_-|BamA/TamA-family-outer-membrane-protein	unknown	unknown	gnl|CDD|130065
NC_019678.1|WP_015121734.1|7340153_7343126_+|zinc-dependent-metalloprotease	unknown	unknown	gnl|CDD|379818
NC_019678.1|WP_015121735.1|7343284_7345657_-|glycoside-hydrolase-family-65-protein	unknown	unknown	gnl|CDD|224471
NC_019678.1|WP_015121729.1|7334495_7335068_-|DUF3727-domain-containing-protein	unknown	unknown	gnl|CDD|372165
NC_019678.1|WP_015121732.1|7337555_7337756_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121723.1|7325381_7326749_+|hypothetical-protein	unknown	unknown	gnl|CDD|274604
NC_019678.1|WP_015121721.1|7320738_7322505_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_019678.1|WP_015121731.1|7335746_7337003_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379228
NC_019678.1|WP_015121724.1|7326921_7327470_-|RNA-2'-phosphotransferase	unknown	unknown	gnl|CDD|179136
NC_019678.1|WP_044292466.1|7345844_7346597_-|beta-phosphoglucomutase-family-hydrolase	unknown	unknown	gnl|CDD|213673
NC_019678.1|WP_015121733.1|7337917_7339639_-|putative-low-complexity-protein	unknown	unknown	gnl|CDD|224276
NC_019678.1|WP_015121728.1|7330591_7333666_+|serine-protease	unknown	unknown	gnl|CDD|274350
NC_019678.1|WP_015121737.1|7347361_7348099_-|DUF1995-family-protein	unknown	unknown	gnl|CDD|370448

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_083894156.1|7316487_7317414_+|site-specific-DNA-methyltransferase	gnl|CDD|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	6.06629e-34
NC_019678.1|WP_015121730.1|7335229_7335742_-|Holliday-junction-resolvase-RuvX	gnl|CDD|234639	PRK00109, PRK00109, Holliday junction resolvase RuvX.	1.3832e-55
NC_019678.1|WP_015121727.1|7330010_7330532_+|hypothetical-protein	gnl|CDD|372967	pfam14218, COP23, Circadian oscillating protein COP23. This family includes the circadian oscillating protein COP23 from Cyanothece sp. (strain PCC 8801). The levels of this peripheral membrane protein display a circadian oscillation.	2.73988e-47
NC_019678.1|WP_015121720.1|7317816_7318791_+|lysophospholipase-L1-like-esterase	gnl|CDD|238866	cd01828, sialate_O-acetylesterase_like2, sialate_O-acetylesterase_like subfamily of the SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	1.13358e-66
NC_019678.1|WP_015121726.1|7328520_7329900_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.78248e-68
NC_019678.1|WP_015121738.1|7348266_7349436_-|cysteine-desulfurase	gnl|CDD|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	1.88912e-178
NC_019678.1|WP_015121722.1|7323057_7325214_-|BamA/TamA-family-outer-membrane-protein	gnl|CDD|130065	TIGR00992, chloroplast_import-associated_channel_homolog, chloroplast envelope protein translocase, IAP75 family. Two families of proteins are involved in the chloroplast envelope import appartus.They are the three proteins of the outer membrane (TOC) and four proteins in the inner membrane (TIC). This family is specific for the TOC IAP75 protein. [Transport and binding proteins, Amino acids, peptides and amines].	4.42402e-104
NC_019678.1|WP_015121734.1|7340153_7343126_+|zinc-dependent-metalloprotease	gnl|CDD|379818	pfam16313, DUF4953, Met-zincin. This is a family of uncharacterized proteins that carry the highly characteristic met-zincin mmotif HExxHxxGxxH, the extended zinc-binding domain of metallopeptidases.	2.21461e-106
NC_019678.1|WP_015121735.1|7343284_7345657_-|glycoside-hydrolase-family-65-protein	gnl|CDD|224471	COG1554, ATH1, Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism].	0
NC_019678.1|WP_015121729.1|7334495_7335068_-|DUF3727-domain-containing-protein	gnl|CDD|372165	pfam12527, DUF3727, Protein of unknown function (DUF3727). This domain family is found in bacteria and eukaryotes, and is approximately 100 amino acids in length.	6.83344e-38
NC_019678.1|WP_015121723.1|7325381_7326749_+|hypothetical-protein	gnl|CDD|274604	TIGR03492, TIGR03492, conserved hypothetical protein. This protein family is restricted to the Cyanobacteria, in one or two copies, save for instances in the genus Deinococcus. This protein shows some sequence similarity, especially toward the C-terminus, to lipid-A-disaccharide synthase (TIGR00215 or pfam02684). The function is unknown.	1.13259e-178
NC_019678.1|WP_015121721.1|7320738_7322505_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.1106e-79
NC_019678.1|WP_015121731.1|7335746_7337003_-|GNAT-family-N-acetyltransferase	gnl|CDD|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	5.16173e-05
NC_019678.1|WP_015121724.1|7326921_7327470_-|RNA-2'-phosphotransferase	gnl|CDD|179136	PRK00819, PRK00819, RNA 2'-phosphotransferase; Reviewed.	6.33161e-97
NC_019678.1|WP_044292466.1|7345844_7346597_-|beta-phosphoglucomutase-family-hydrolase	gnl|CDD|213673	TIGR02009, Hypothetical_protein_Rv3400/MT3508/Mb3433., beta-phosphoglucomutase family hydrolase. This subfamily model groups together three clades: the characterized beta-phosphoglucomutases (including those from E.coli, B.subtilus and L.lactis, TIGR01990), a clade of putative bPGM's from mycobacteria and a clade including the uncharacterized E.coli and H.influenzae yqaB genes which may prove to be beta-mutases of a related 1-phosphosugar. All of these are members of the larger Haloacid dehalogenase (HAD) subfamily IA and include the "variant 3" glu-asp version of the third conserved HAD domain (TIGR01509).	6.55607e-51
NC_019678.1|WP_015121733.1|7337917_7339639_-|putative-low-complexity-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.45723e-39
NC_019678.1|WP_015121728.1|7330591_7333666_+|serine-protease	gnl|CDD|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	5.03958e-25
NC_019678.1|WP_015121737.1|7347361_7348099_-|DUF1995-family-protein	gnl|CDD|370448	pfam09353, DUF1995, Domain of unknown function (DUF1995). This family of proteins are functionally uncharacterized.	5.09238e-81

Protein sequences

>NC_019678.1|WP_015121728.1|7330591_7333666_+|serine-protease
MKPHRTYFRQSLALIACMGSLLMLPMAESLSISHGKVSAQQPTPQLSPQQIKQLAQSITVKVSSGNNGGSGILLKKSGGVYTVLTNRHVLEPGKPIKLQTSDGKTHRGKVVQGVDFQGKDLIQLQFSSNEKYKVAELGNLATVAINETIYAGGFPFETNPSETQGFVLTTGQVLLIAERALKEGYQIGYDNDIRKGMSGGPILNRYGQLIGINGIHAHPLWGNPYVYEDGSNPTEARRDLMSRYSWGIPILTATSLASKSDSTKAQVPVSKLPPIANEVNNIAEKITVRIDVPNSPECSGSGVIIAKKQNTYTVLTAEHVIREDVKCDRRVLSLVTHDNRSYPIQVNDNSVKTAPGSDLALLEFNSNQTYDVATLADYQQGQNIGFVFISGWIGSESNSSSPQREFTAGFLTPKELGLFLAKNPLSLEYGYSLFYTNMTHKGMSGGPVLDTRGRVIGIHGKAEKQEIKDKAGRNRLIPLGFSLGIPMSKFVSWAQQVGITSVLRVETSVPPALTKKERNDIRQALLQVKKLGDNADAIDWLNYGWEVFLSNGSESEAIKAVDRAIQNKPDFYQAWYLRGLMNGLDKKSLKDFEKAISIEPKFTPAWRIRGFTLFHLDQYPEALSSFEQLVKIDSKDVSANTFRSLILLSQGNFTEALDIANLAFANSRNPDAWMYLVRAFALVANGDSKRAMANLDEAVRLNPEFMKGYVYSTRGNLRSQQGDLKGALADFNEAVLFEPEKVDYLKKRADIRSQLKDYKGAIADYTEAVRLNPKDSDAIKKLLVIRIEQKDFNGAITDLNKFISLNPKNIDAIKARGVVRFAQKDYENALADFNEVIRLKPDDSDSYYYRGQTLTQLNNYQAAVENYNQILHTEKFDGVIGINVEINSKTKVATVTQVKDNYSAQKQGIKVGDQILVVDGKSTKNMSLKQVVDLLRGKAGTKLSVRVARSGNNKLDFNLTRIELATTDIDAKFAKVYYQRGLTRIKLKDNQGARKDLQIAAELYNREGKKNEYQQALAKIKELQ
>NC_019678.1|WP_015121727.1|7330010_7330532_+|hypothetical-protein
MKIRSIFQALTTGMITLGVFSAVSPSTVAQAQPKKTYFCGQSKNGNWTTFARNYNNRRIPVIYWVKKLGGYTPKMRCEVISPKFQSAYKSGILNYLTSGVHRGQPVICATSQYGGPCSQILFTLKSHREASSVLQQLINVGYRAGDGGVFQSGNSSGVYIDMQRLLTAESQTK
>NC_019678.1|WP_015121726.1|7328520_7329900_+|protein-kinase
MIGKILDGRYEIISKLGQGGFGTTYLAIDRKLPDKDRCVVKHFSPLVTDANSLFHARRLFENEAKTLNRLGNHNQIPRLLAHFEEEEEFYLVQEYVAGKDLSSEITRNKQWNEQDVIALLLDVLEVLQFVHQNNVIHRDIKPSNLIRRRHDGKIFLVDFGAVKQISSHTVSSGGRTIGIGTCGYMPSEQSQGEPRLCSDIYAVGIIGIQALTGLPVTHIAKDSVTNEIICDEQKQVSPKLAKVLKKMVRYHPQERYPSASEALEALQNITPAYSVTKSIQLKTFVGLAAIALVTFIGSWLFLIPRNDLDIYQNTLYGISIKYPQKWQKSVTPDRITGNLAKFMPPMADTDTYPENINLIVRDLPENRQELKQFTNSYLDDIKQVYPDAEIIQQGKTELNNQPAYQVIYTTKDNENNIQRLQIWTVKNNKAYVITYTANINKYSQYLDIAQRMIHSFEIE
>NC_019678.1|WP_157229342.1|7327576_7328083_-|hypothetical-protein
MMNKALRSAWEEFQYMISQIDNQDNGITIFKCIQTWYLDNKKLLSPRLIEEYGLEELINIDTAYYPLEKSECTSEEIKRFLKLQPSSEECMIVWLRDILWELVVLSVDIECKNCGKLEMSALFNIKTENVFFECTQCGWVKTIDGYSDESIKTIRLATNQDLKIAGLI
>NC_019678.1|WP_015121724.1|7326921_7327470_-|RNA-2'-phosphotransferase
MNNSRLTKVSKYLSKHLRHQPERIGIKLAAGGWVEVDELLEACRKNKFPVTRADLEEVVANNDKKRFSFDSTGTKIRANQGHSVEVDLQLLPSVPPDVLYHGTGHKTVGVIMANGLSKMSRHHVHLSFDIGTAKKVGARHGKAVVFAVDAAKMYEAGFVFYCSDNGVWLTDNVPAQYLKVIN
>NC_019678.1|WP_015121723.1|7325381_7326749_+|hypothetical-protein
MSEISPLTFTKKSQATTSNLRLLVLSNGHGEDVIAVRILRELQQQDSSPEIFALPLVGEGHAYQKLDIPVIGSVRSMPSGGFIYQDARQLSKDVRSGLLKLTLNQFKAIRRWVKTQKKSGYSPKILAVGDIVPLLFAWLSGSKYAFVGTAKSEYYLRDETGWLKRDTQAARWEGWSGSVYLPWERWLMSRQRCQAVFPRDSLTTEILKQWKIPAFDLGNPMMDGLEPSFPQKRFYASDTRKQEIERPLAIALLPGSRIPEAYKNWEKITVAVSALIATFREQDFIGHTSGNIVFLAGIAPGLDCNILAKTLKNQGWNIVPNEDSPINIPDNRALTLKHKNAFLILSQTAYNDCLHLGDIAIAMAGTATEQFVGLGKPAIIIPGEGPQFTPLFAEAQTRLLGSSVILVKQPSDVASQITNLFNNPDRLHMIANNGKRRMGKPGAAERIAESLMKNW
>NC_019678.1|WP_015121722.1|7323057_7325214_-|BamA/TamA-family-outer-membrane-protein
MRISSAAIFTLAALAATNIDNKATAANDSTPLSEEQKAENIVVPVIEDTPAPEQAIAQPETLPVQQFSSVSSVSDSVSRGDMQLSVNSKQLPVNSKGVESQKQENIKQKQIVIKNSPAPLRSPSPTPPLPPSGTPVKPKSDFVVPATNVQIVGVSPELQQVIKGVIKTQPGADTSQTQLKQDVAAISETGLFAGATVNSRSNEQGLSVVFQAKPVVVRSLQLSNAKALSYQVAQKVFQSQIGKPISPVAMKKAVEDINKWYTENNYSLARVTSIKPNSQGVLDINVAEGLIGNIKFRFINDDNKTVDKKGKPIEGRTKPEFITKQIQVKSGQIFKENRVRQDVQRLYATGLFERVNLELEGDANKVDVVYYIKEAGARSVNVGGNYSADQGIVGTLNYNDRNVGGINENLNVNLQLSRRDLNFDTRFTSPYRANNPNRLGYSLNAFRKRQLSNTFNDDIKLANDDKVREGKFGGSVTLQRPIDGWNTTLGFNYTRVSITDSKGKVQAVDAQNNPLTKSGTGIDDLATVSLNAVKDRRNNPFNPTKGSVVKLSTEQSLPFGQGEISMNRLKADYTQYVPVKLFKSSQTQVFALNVQAGTVLGDLPPYESFGLGGSNSVRGYGAGDVGNGRSYVLASAEYRFPMPILDSLGGVLFADFATDLGSGDTVVGDPAGVRNKPGEGFGYGAGVRLNSPLGLIRADYGVNNQGDTRVHFGIGHRF
>NC_019678.1|WP_015121721.1|7320738_7322505_-|serine/threonine-protein-kinase
MLTGKTLQGGKYTINQEIGRGGFGITYKATHHFLHQEVVIKTLNHKLQKHPDFAKFERQFQDEARRLASCVHPNIVRVSDFFIEADFPYMVMEYIPGETLGEAFVMPGIPLPEDQAIHYIRQIGAALGAVHLKGLLHRDVKPDNIILRQNTNEVILIDFGIAREFNAGARQNHTGMVSEGYSPMEQYLTKAKRSAATDVYGLASTLYALLTAQVPMPVLLRDKEKMPSPRELQPHLSAAVNQAVMRGMAVEARFRPQTVAEWLDLLPDMTRRTVIQPVPTHAVPTIDLSTQEYEANVPPQAVAVMNPHVPSTQVNSEQTNGEVKEPWFKKMPSPRVLIGTGVAIFGVTLGFGLTKIASTAERQPKVAPALEKPVNETAAEILPSVELPYPSPSASPSTSPTPQETEAAKEVKTPPVNKTTKPRRIRRRARTKTRSAAASYTPKQRRRSNSSKKSSTRKSSSPSKVTEKKSTPTTSKKSTSSQSTSRQSTKRSYPKKTNTSSGASQRRRNTTSKPKRNSIPPKKVVPSPSLVERLRKVRDSRSNSSSPKNSVKLKPAKKPNKPVIVPAKPAAQSRNSNPPAVVVPTQQQ
>NC_019678.1|WP_015121720.1|7317816_7318791_+|lysophospholipase-L1-like-esterase
MRKFYLVAASLLIGLTLPKSAFTQLSAINPEHYQLLLNRKNGWQKTKLEDTASASDSVSQNFSPPAQSSYNPPAPIRRRLISGSQLYHERLAALKAGYIYTRLAKEKLQSLLITRRKPKLTYQDWKRLLALEARAMTKGQGNNRLSIMLGDSLSLWFPTNGLPSGKLWLNQGISGDTSTGILRRISAFSSTKPEVIYIMAGINDLRKGTSDKVILSNHRRIVRRLKITHPNSYIVIQSILPTRRPKISNNRIRNLNTQLARIAKEEKVNYVNIHKWFADFKGDLRQDLTTDGLHLSLNGYEVWQAAIEQIEKKLALSKAVGTWR
>NC_019678.1|WP_083894156.1|7316487_7317414_+|site-specific-DNA-methyltransferase
MKRRKTKVIKFAPYYSQNFGKAYLGNSLQLIKNLNDNSINLIVTSPPFALTRQKEYGNESADKYIEWFLPFAYEFKRVLTDDGSFILDLGGAYRPGLPVRSLYQYELLLKLCKTVGFHLAQELYHYNPARLPTPAEWVTVKRIRVKDSVNMVWWLSKTPYPKADNTKVLKPYSKSMKNLLEKGYEAKLRPSGHDISDKFQKDNKGAIPPNFLEPQNFLKIGNTESNSAYMRRCKKAGIKPHPARFPRGFAEFFIKFLTDENDTVLDPFAGSNTTGFVAETLQRRWVSFEIDENYLIGSKHRFGDEEID
>NC_019678.1|WP_015121729.1|7334495_7335068_-|DUF3727-domain-containing-protein
MYPSQFPEENERSNQSSITLTDETGRSLECYVEHSLEVDEQEYFLLLPADSPVEIFAWQTDGDGEEAVLVEDDFTIEKIFSTAQAVLSEQNLVLKNTAYALTAAGDLPTVEESDIFTLEIEDEEADLEPEQLQLLASFYWEEQEYAIYTPLDPLLFFARINSEGKPELLSPEEFREFQPLLEELLFNEVE
>NC_019678.1|WP_015121730.1|7335229_7335742_-|Holliday-junction-resolvase-RuvX
MVPQEGRGDEVNDEISSQTPKSTNRTSYISALGLDVGRKRIGIAGCDRTGLIATGLTTVHRTTFLQDVEQIKQIIQEREVEILVVGLPYSMDGSLGFQARQVQKFTKSLTAILKLPVEYVDERLTSYQAKQMIIAEKRSPSRNKGLVDRKAAALILQQWLDIRRQQKTES
>NC_019678.1|WP_015121731.1|7335746_7337003_-|GNAT-family-N-acetyltransferase
MKMTSLLSQNINIVIRPVQYRDLDDIERLSQESFAAQKPNEEHFATQQERKLRRNFGLFKFLSWFPNPLQHRLCAYVAEQGRTMLGIIQVSPFNKTRSTWRVDRVMLEKCVNKQAIGSQLLRYCFESILEARTWILEANVNDKEALALYRQNGFQRLAEMTYWEVEPELLASLAQAEPDLPNLLPVSNADAQLLYQLDTASMPPLVRQVFDRQTHDFKTGLIGALADAVKQWLTKSEIVSGYVFEPQRKAAIGYFQLRIDRKGETPHVATLTVHPAYTWLYPELLSQMARITQDFPSSSLKVASADYQPEGEEYLEQIGASRIEHTLIMSRSVWHKVRESKFVSLEGIQLPEMLQGLQPARKPIPGGMLWKQEKRRQMLERAKLNKLSKLSKDNIALPYQKGNVEGNNTNPSTDNPQE
>NC_019678.1|WP_015121732.1|7337555_7337756_-|hypothetical-protein
MESNTFTSNQGAREEFSEYVAHLQFHMTLQARNLVPSLKQNSDDSRGELLHQTQADFEKVISRQVI
>NC_019678.1|WP_015121733.1|7337917_7339639_-|putative-low-complexity-protein
MLQIEFLKQLWRNCLRQSRLEEVPHTATGESRAIEIATIADRLPSKQVESFEDNLLSSSFKKKLEASLIEWAQASNDFASNVDRRQFYKHIYALLGNVTLKPEVVESAIAQFMARDKENPVILFEKLENFYRRWCDGEFIDAAPDNNLPQQQMLQLQSQNIAIRLRELDINTGLNVMILLLEIHQVIREQNHHLQDKIAFYSSDKPDSEHFFTSTLLRVINYSDSIGIGNFTNVVGEFLKGAFLENVYLGDANLTGANLSHAKLNGAYLGDANLTGVQGKKIKLRSANLGDANLSGADFREANLTDCDLTHCNLSGADLSGANLTGANLGDANLTGANLAGANLTGANLTSANIRDAVLSGANLKNSIFFGANLSDADLIGVELSYADLCRADLSGVNLRGSTLRGTNLSDSLMFGTNLKEAILIAADLSYAKLNSANLGGANLQGAIILGADLGGVDLSQVILNEADLSGVSLNEANLSSADLSDAVLLGTDLSYANLSNANLSGSNLTGAIFSGADLSDSNISYAILSNVDFNEANLENATWNENLEWDRVRGLDKALNVPEALKDKFRLS
>NC_019678.1|WP_015121734.1|7340153_7343126_+|zinc-dependent-metalloprotease
MKTKSVYLILLRSLYLAAAIFGVQSLSVAAKVAARLNQQTPQENILTEKLDFKTAETSNNTLAVNKINQKHIEKLSPGKVWVLEKEKEVQADLFTWVVNDTKKSAQQPFLQLNKQQKKPASKPSSKPKPAKKPAKKDGFKAFDKVVKDTKISKGLFTLYRNKEKNQIYLEVKPTQFKKNYLATATLESGIGEAGIYSGMPLQDFLFYFERVGDNLHFVVRNVNFRAQEGDPQARSLARSFSDSVLYKIKIKSIHPQRKSVLIDLGDLLLTDLAGLSSSLGVPGSQDKSYFGSAKVFPKNIEVQSILNFSVTGSGKRRNKFRTLADNRGFTLKLHYSLSELPDNNYRPRLADERVGYFITAYQDLSTKDPSDPFVRYVNRWNLEKKYPNASISEPKKPIVYWIDNATPYEYRDAIKEGVLMWNRAFEAAGFKNAIEVKQMPDSATWDPSDIRYNTIRWINTVDGYFAMGPSRVNPLTGEILDADILIDASLVSSLKKDYRQMVQPTQSSKKITSLSAMMQNRLLCRNGLEAEDTDSEEIPVIKRLSSLASKYDLCYGIEATNQFGYGKLAISLLRDLPPTSQETKEYIHQYLRLIVAHEVGHTLGLRHNFRGSTMLSPEEMNDRSITRSRGQVASVMDYIPPNIAPESIKQGDYFPSIVGPYDAWAIKYGYSQIKAASTKAEEPVLREIASESYKPEYSYSTDEDVYDLDPTADAWDNSSNVLLYSKWQMDNARKMWDRINKRYPLVGESYSDVRERFGAVLNNYFQQIYYTSKYIGGQSFYRVYASENQTRLPFEPVPVEKQRQALEVLGDYIFAEDAFDFSPELLNKLAPSRWRHWGSNPQVGRLDYPIHDLVLFMQNMVLYDLLSSDRLSRLKDIELKSRSGEALTLPELFNTLQDSIWTEVLKPKDKDIEISSLRRGLQRKYLDILTNMVLRKVNVPEDARTLAWYKLRQLAEKLDDANSEDEYTKAHLLETRQRISKVLNAPLRTN
>NC_019678.1|WP_015121735.1|7343284_7345657_-|glycoside-hydrolase-family-65-protein
MLRREPLNPPKYVYPVDEWRMVEKQYYPRFQAQMETIFSIGNGYLGMRGVCEEVTPCTENGTFINGFYESWPIVYGEEAFGFAKTGQTIVNVTDSKIIKLYVDDEPFSLSTANLLSFERVLDMKAGTLNRKLVWETPSGKKVAIKSRRLISLEHRHLAAIEYEVTLLNAKAPVVISSEMENHKHKAANNHDPRKAKGFKGRVLNPKVNYCQEGRVLLGYVTNQTKIGLACGIEHEILTDCSYFYKSECSEDDGKAVFNIDALPGVPIKLIKYITYNTSPGHAIEELCTRAHRTLDRAEKLGFEAILASQQQYMDEFWHKSDIKIYGNPYDTDATRALELQQAIRFNLFQILQASARAEGTGIPAKGLSGQAYEGQFFWDTEIYVLPFLIYTAPRIARNLLQFRYKMLDKARKRARQLNQKGALFPWRTINGEEASAYYAAGTAQYHINADIAYAIKKYVEITGDKDFLYNEGVEILVETARLWHDLGFFQDGKFHIHGVTGPDEYTTVVNNNAYTNLMARENLRYAAQTVQMLQNEDLERFSALLDRTNLALVEIEEWQKAVDNMYIPYDEAKGIHPQDDSFLSKKVWDFENVPRSKYPLLLNFHPLVIYRHQVIKQADVVLAMHLLGQEFSEEQKKRNFDYYDPLTTGDSSLSVCIQSILAFQLGYSQKALEYAYFAVLMDLADIAGNSKDGCHIASMGGSWMLMVYGFAGMKDYNGNLSFHPRLPKGTKRLHFPLTICCQRLEVDIRQEEVTYLLREGSELRIKHQDEEILLKVGVPVCIKQKVQDWE
>NC_019678.1|WP_044292466.1|7345844_7346597_-|beta-phosphoglucomutase-family-hydrolase
MSQSNYSVTSDKFDAVLFDLDGVLTATAKVHAVSWKRMFDEFLSKHSQENNLSFVPFEIDTDYKHYVDGKPRSNGLRSFLKVRGIELAEGTPDISAEEDTVYGLGKRKDEIFHSILQSDGVEVYETSVAWVCYLRSQDIKTAVVSSSRNCEAVLKAADITDLFAARVDGKVAASLGIAGKPAPDTYLKAAQLLNVEPKRCVVVEDAISGVQAGSAGGFGLVIGVNRNDDADALINNGADIVVTDLGEMLQ
>NC_019678.1|WP_015121737.1|7347361_7348099_-|DUF1995-family-protein
MSELPKTLEDAIVQARAATQAALADGYTRLQVELLFPELKALPAAQQFLPAFDEYGDKLKIFFADAGSAALARRDWNEIPFQLLDIGTGRMTSIESKVQPEDEIFLFVQPSSVEVPQLEKLCGIIGEQRPFVMFAPRLEDSSIVGIGYAARQTRQRFINTIESCYYLRPIFEEAAVFRCYPGLWEVWVEKNGDYEKVAELPNKPSGDELDAIISGTEAQAEGETVAATSKSVFRGLQRFVKALRS
>NC_019678.1|WP_015121738.1|7348266_7349436_-|cysteine-desulfurase
MQIYLDYSATTPTRPEAINMMHTVLTQGWGNPSSLHEWGQRAATIVEQARMQVASLIGAPWHESIVFTSGGTEADNLAVMGVAQLFREPQHIIISSVEHSAISEPAKLLENWGWEVTRLHVDNKGRVNPDNLKAALKDNTVLISVIYGQSEVGTVQPIEEIGKIARSAGVLFHTDAVQVAGRLPIDVRKLSVDLLSISSHKIYGPQGVGALYVRPEVELVPLLNGGGQEMRSRSGTQAVPIIAGFGIAAELAAQELPIETPRLIELRDRLFSQLADVEGLIPTGDLIQRLPHHASFCLKYADGQKISGKTIVRQLNLAGIGISAGSACHSGKLSPSPVLTAMGYSDKAAMGGIRITLGRYTTQADIDWVAMVLKQVMSRLENRFALVTK

Crispr_ID: NC_019678_38

• CRISPR_ID: NC_019678_38
• CRISPR_location: 7450340-7451660
• CRISPR_type: Orphan
• Repeat_type: A:N
• Spacer_info: 18 spacers

Consensus repeat of NC_019678_38

Consensus_repeat	Method
GTT----------TCAATCCCTAATAGGGATTAGAGGTTATTTCAAC	PILER-CR
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CRISPRCasFinder
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CRT

spacers of NC_019678_38

>38.1|7450377|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CCAAGTCTTAGTAATTACAGCCATTTTGATTTTTT
>38.2|7450449|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CTACCACGCATGATTGCGGATTTTAACACAGCTT
>38.3|7450520|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AGAAAAATATTTAAGCTATTCGAGGCTGAATTTTC
>38.4|7450592|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTATAACCTTTGCTTGTTTGCTCAAGTACTAAA
>38.5|7450662|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CAGAGCTTTCAACTGCCTGCATAGGTTCAGAAGTT
>38.6|7450734|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CAGGATTATTCCCAGGCTTTCTCATAGTCACTAA
>38.7|7450805|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GAAAAGTCCTGCCCAGTATACTTGGGACAGTATC
>38.8|7450876|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTAAGATTGAAGCGGTACGCTACTTTGTTACTAA
>38.9|7450947|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTAGAACCCGTTGCCGCTTAACCCTCACTCCCAAC
>38.10|7451019|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT
ACTCTGATTCTTGCGGGCTCAAAAACTCTTTCC
>38.11|7451089|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AAATTACTTTTCTACACAGGTGCTAGACCTTCAG
>38.12|7451160|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GTGGGGTGAGTACTTCTAAAACATTCACCACATCT
>38.13|7451232|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TTTTAGCTTTAGATAATGAATCGATGGCTAAAAAG
>38.14|7451304|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GTCGCTGCAAATTTCTCTAATCCGGCAACGAATT
>38.15|7451375|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
TATTTGTTAGCATCAATATATCACACCTGTAGAT
>38.16|7451446|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
AAAATTTCTACCTAAAGAGCTATTTGTTGCTATCT
>38.17|7451518|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT
CACTTCTTGAGCAAACATTTGGCGATTCACTTTA
>38.18|7451589|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT
GTTTCCGCTTCGACTCCCGTACAGCCTCAGCTTCC

CRISPR arrays and Neighbor proteins around NC_019678_38

CRISPR arrays

The CRISPR arrays of NC_019678_38

>merge|NC_019678|38|7450340-7451660|PILER-CR,CRISPRCasFinder,CRT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACCCAAGTCTTAGTAATTACAGCCATTTTGATTTTTTGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACCTACCACGCATGATTGCGGATTTTAACACAGCTTGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACAGAAAAATATTTAAGCTATTCGAGGCTGAATTTTCGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACTTATAACCTTTGCTTGTTTGCTCAAGTACTAAAGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACCAGAGCTTTCAACTGCCTGCATAGGTTCAGAAGTTGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACCAGGATTATTCCCAGGCTTTCTCATAGTCACTAAGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACGAAAAGTCCTGCCCAGTATACTTGGGACAGTATCGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACTTAAGATTGAAGCGGTACGCTACTTTGTTACTAAGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACTTAGAACCCGTTGCCGCTTAACCCTCACTCCCAACGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACACTCTGATTCTTGCGGGCTCAAAAACTCTTTCCGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACAAATTACTTTTCTACACAGGTGCTAGACCTTCAGGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACGTGGGGTGAGTACTTCTAAAACATTCACCACATCTGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACTTTTAGCTTTAGATAATGAATCGATGGCTAAAAAGGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACGTCGCTGCAAATTTCTCTAATCCGGCAACGAATTGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACTATTTGTTAGCATCAATATATCACACCTGTAGATGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACAAAATTTCTACCTAAAGAGCTATTTGTTGCTATCTGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACCACTTCTTGAGCAAACATTTGGCGATTCACTTTAGTTGAAATAACCTCTAATCCCTATTAGGGATTGAAACGTTTCCGCTTCGACTCCCGTACAGCCTCAGCTTCCGTTGAAATAGCCTCTAATCCCTATTAGGGATTGAAAC

>NC_019678|38|16|7450340-7451660|PILER-CR
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CCAAGTCTTAGTAATTACAGCCATTTTGATTTTTT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CTACCACGCATGATTGCGGATTTTAACACAGCTT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	AGAAAAATATTTAAGCTATTCGAGGCTGAATTTTC
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	TTATAACCTTTGCTTGTTTGCTCAAGTACTAAA
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CAGAGCTTTCAACTGCCTGCATAGGTTCAGAAGTT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CAGGATTATTCCCAGGCTTTCTCATAGTCACTAA
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	GAAAAGTCCTGCCCAGTATACTTGGGACAGTATC
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	TTAAGATTGAAGCGGTACGCTACTTTGTTACTAA
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	TTAGAACCCGTTGCCGCTTAACCCTCACTCCCAAC
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	ACTCTGATTCTTGCGGGCTCAAAAACTCTTTCC
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	AAATTACTTTTCTACACAGGTGCTAGACCTTCAG
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	GTGGGGTGAGTACTTCTAAAACATTCACCACATCT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	TTTTAGCTTTAGATAATGAATCGATGGCTAAAAAG
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	GTCGCTGCAAATTTCTCTAATCCGGCAACGAATT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	TATTTGTTAGCATCAATATATCACACCTGTAGAT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	AAAATTTCTACCTAAAGAGCTATTTGTTGCTATCT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CACTTCTTGAGCAAACATTTGGCGATTCACTTTA
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	GTTTCCGCTTCGACTCCCGTACAGCCTCAGCTTCC
GTTGAAATAGCCTCTAATCCCTATTAGGGATTGAAAC

>NC_019678|38|35|7450340-7451660|CRISPRCasFinder
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CCAAGTCTTAGTAATTACAGCCATTTTGATTTTTT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CTACCACGCATGATTGCGGATTTTAACACAGCTT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	AGAAAAATATTTAAGCTATTCGAGGCTGAATTTTC
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	TTATAACCTTTGCTTGTTTGCTCAAGTACTAAA
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CAGAGCTTTCAACTGCCTGCATAGGTTCAGAAGTT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CAGGATTATTCCCAGGCTTTCTCATAGTCACTAA
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	GAAAAGTCCTGCCCAGTATACTTGGGACAGTATC
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	TTAAGATTGAAGCGGTACGCTACTTTGTTACTAA
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	TTAGAACCCGTTGCCGCTTAACCCTCACTCCCAAC
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	ACTCTGATTCTTGCGGGCTCAAAAACTCTTTCC
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	AAATTACTTTTCTACACAGGTGCTAGACCTTCAG
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	GTGGGGTGAGTACTTCTAAAACATTCACCACATCT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	TTTTAGCTTTAGATAATGAATCGATGGCTAAAAAG
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	GTCGCTGCAAATTTCTCTAATCCGGCAACGAATT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	TATTTGTTAGCATCAATATATCACACCTGTAGAT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	AAAATTTCTACCTAAAGAGCTATTTGTTGCTATCT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CACTTCTTGAGCAAACATTTGGCGATTCACTTTA
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	GTTTCCGCTTCGACTCCCGTACAGCCTCAGCTTCC
GTTGAAATAGCCTCTAATCCCTATTAGGGATTGAAAC

>NC_019678|38|15|7450340-7451660|CRT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CCAAGTCTTAGTAATTACAGCCATTTTGATTTTTT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CTACCACGCATGATTGCGGATTTTAACACAGCTT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	AGAAAAATATTTAAGCTATTCGAGGCTGAATTTTC
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	TTATAACCTTTGCTTGTTTGCTCAAGTACTAAA
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CAGAGCTTTCAACTGCCTGCATAGGTTCAGAAGTT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CAGGATTATTCCCAGGCTTTCTCATAGTCACTAA
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	GAAAAGTCCTGCCCAGTATACTTGGGACAGTATC
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	TTAAGATTGAAGCGGTACGCTACTTTGTTACTAA
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	TTAGAACCCGTTGCCGCTTAACCCTCACTCCCAAC
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	ACTCTGATTCTTGCGGGCTCAAAAACTCTTTCC
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	AAATTACTTTTCTACACAGGTGCTAGACCTTCAG
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	GTGGGGTGAGTACTTCTAAAACATTCACCACATCT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	TTTTAGCTTTAGATAATGAATCGATGGCTAAAAAG
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	GTCGCTGCAAATTTCTCTAATCCGGCAACGAATT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	TATTTGTTAGCATCAATATATCACACCTGTAGAT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	AAAATTTCTACCTAAAGAGCTATTTGTTGCTATCT
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	CACTTCTTGAGCAAACATTTGGCGATTCACTTTA
GTTGAAATAACCTCTAATCCCTATTAGGGATTGAAAC	GTTTCCGCTTCGACTCCCGTACAGCCTCAGCTTCC
GTTGAAATAGCCTCTAATCCCTATTAGGGATTGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019678.1|WP_015121815.1|7452167_7453079_-|ChaN-family-lipoprotein	unknown	unknown	gnl|CDD|377239
NC_019678.1|WP_015121807.1|7440406_7441705_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|183282
NC_019678.1|WP_015121817.1|7453498_7454488_-|chlorophyll-synthase-ChlG	unknown	unknown	gnl|CDD|131111
NC_019678.1|WP_015121806.1|7438442_7439648_-|MFS-transporter	unknown	unknown	gnl|CDD|341026
NC_019678.1|WP_015121812.1|7447280_7448426_+|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121818.1|7454684_7455785_-|ArsA-family-ATPase	unknown	unknown	gnl|CDD|223082
NC_019678.1|WP_015121809.1|7442914_7443055_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121808.1|7441882_7442716_-|fatty-acid-desaturase	unknown	unknown	gnl|CDD|224316
NC_019678.1|WP_015121821.1|7457314_7458388_+|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl|CDD|224014
NC_019678.1|WP_015121814.1|7449595_7450105_+|sterol-desaturase-family-protein	unknown	unknown	gnl|CDD|377224
NC_019678.1|WP_015121823.1|7459803_7461606_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|379312
NC_019678.1|WP_015121810.1|7444405_7445530_+|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	unknown	unknown	gnl|CDD|226985
NC_019678.1|WP_044292480.1|7455856_7456054_-|DUF2862-domain-containing-protein	unknown	unknown	gnl|CDD|371361
NC_019678.1|WP_015121824.1|7461673_7463092_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|379312
NC_019678.1|WP_015121805.1|7437013_7438261_-|CapA-family-protein	unknown	unknown	gnl|CDD|378215
NC_019678.1|WP_015121816.1|7453093_7453372_-|hypothetical-protein	unknown	unknown	unknown
NC_019678.1|WP_015121822.1|7458455_7459760_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213187
NC_019678.1|WP_015121820.1|7456416_7457274_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224596
NC_019678.1|WP_015121811.1|7445640_7446927_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|99747
NC_019678.1|WP_015121813.1|7448422_7449394_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|187539

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019678.1|WP_015121815.1|7452167_7453079_-|ChaN-family-lipoprotein	gnl|CDD|377239	pfam04187, Cofac_haem_bdg, Haem-binding uptake, Tiki superfamily, ChaN. This is a family of putative bacterial lipoproteins necessary for the uptake of haem-iron. The structure of UniProtKB:Q0PBW2, Structure 2g5g, comprises a large parallel beta-sheet with flanking alpha-helices and a smaller domain consisting of alpha-helices. Two cofacial haem groups (~3.5 Angstom apart with an inter-iron distance of 4.4 Angstrom) bind in a pocket formed by a dimer of two ChaN monomers.	3.3676e-100
NC_019678.1|WP_015121807.1|7440406_7441705_-|methyltransferase-domain-containing-protein	gnl|CDD|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	5.20457e-120
NC_019678.1|WP_015121817.1|7453498_7454488_-|chlorophyll-synthase-ChlG	gnl|CDD|131111	TIGR02056, chlorophyll_synthase_33_kD_subunit, chlorophyll synthase, ChlG. This model represents the strictly cyanobacterial and plant-specific chlorophyll synthase ChlG. ChlG is the enzyme (esterase) which attaches the side chain moiety onto chlorophyllide a. Both geranylgeranyl and phytyl pyrophosphates are substrates to varying degrees in enzymes from different sources. Thus, ChlG may act as the final or penultimate step in chlorophyll biosynthesis (along with the geranylgeranyl reductase, ChlP). [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll].	2.92558e-177
NC_019678.1|WP_015121806.1|7438442_7439648_-|MFS-transporter	gnl|CDD|341026	cd17473, MFS_arabinose_efflux_permease_like, Putative arabinose efflux permease family transporters of the Major Facilitator Superfamily. This family includes a group of putative arabinose efflux permease family transporters, such as alpha proteobacterium quinolone resistance protein NorA (characterized Staphylococcus aureus Quinolone resistance protein NorA belongs to a different group), Desulfovibrio dechloracetivorans bacillibactin exporter, Vibrio aerogenes antiseptic resistance protein. The biological function of those transporters remain unclear. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.6699e-76
NC_019678.1|WP_015121808.1|7441882_7442716_-|fatty-acid-desaturase	gnl|CDD|224316	COG1398, OLE1, Fatty-acid desaturase [Lipid metabolism].	2.64894e-100
NC_019678.1|WP_015121818.1|7454684_7455785_-|ArsA-family-ATPase	gnl|CDD|223082	COG0003, ArsA, Predicted ATPase involved in chromosome partitioning [Cell division and chromosome partitioning].	2.53408e-49
NC_019678.1|WP_015121822.1|7458455_7459760_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213187	cd03220, ABC_KpsT_Wzt, ATP-binding cassette component of polysaccharide transport system. The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.	9.46766e-106
NC_019678.1|WP_015121821.1|7457314_7458388_+|GDP-mannose-4,6-dehydratase	gnl|CDD|224014	COG1089, Gmd, GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane].	0
NC_019678.1|WP_015121814.1|7449595_7450105_+|sterol-desaturase-family-protein	gnl|CDD|377224	pfam04116, FA_hydroxylase, Fatty acid hydroxylase superfamily. This superfamily includes fatty acid and carotene hydroxylases and sterol desaturases. Beta-carotene hydroxylase is involved in zeaxanthin synthesis by hydroxylating beta-carotene, but the enzyme may be involved in other pathways. This family includes C-5 sterol desaturase and C-4 sterol methyl oxidase. Members of this family are involved in cholesterol biosynthesis and biosynthesis a plant cuticular wax. These enzymes contain two copies of a HXHH motif. Members of this family are integral membrane proteins.	7.39847e-08
NC_019678.1|WP_015121823.1|7459803_7461606_+|methyltransferase-domain-containing-protein	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.32229e-17
NC_019678.1|WP_015121810.1|7444405_7445530_+|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	gnl|CDD|226985	COG4638, HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only].	1.00911e-38
NC_019678.1|WP_044292480.1|7455856_7456054_-|DUF2862-domain-containing-protein	gnl|CDD|371361	pfam11061, DUF2862, Protein of unknown function (DUF2862). This family of proteins has no known function.	2.28626e-26
NC_019678.1|WP_015121824.1|7461673_7463092_+|methyltransferase-domain-containing-protein	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.36694e-16
NC_019678.1|WP_015121805.1|7437013_7438261_-|CapA-family-protein	gnl|CDD|378215	pfam09587, PGA_cap, Bacterial capsule synthesis protein PGA_cap. This protein is a putative poly-gamma-glutamate capsule biosynthesis protein found in bacteria. Poly-gamma-glutamate is a natural polymer that may be involved in virulence and may help bacteria survive in high salt concentrations. It is a surface-associated protein.	3.05873e-91
NC_019678.1|WP_015121820.1|7456416_7457274_+|ABC-transporter-permease	gnl|CDD|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	6.09612e-49
NC_019678.1|WP_015121811.1|7445640_7446927_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|99747	cd06454, KBL_like, KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS), 8-amino-7-oxononanoate synthase (AONS), and 2-amino-3-ketobutyrate CoA ligase (KBL). SPT is responsible for the condensation of L-serine with palmitoyl-CoA to produce 3-ketodihydrospingosine, the reaction of the first step in sphingolipid biosynthesis. ALAS is involved in heme biosynthesis; it catalyzes the synthesis of 5-aminolevulinic acid from glycine and succinyl-coenzyme A. AONS catalyses the decarboxylative condensation of l-alanine and pimeloyl-CoA in the first committed step of biotin biosynthesis. KBL catalyzes the second reaction step of the metabolic degradation pathway for threonine converting 2-amino-3-ketobutyrate, to glycine and acetyl-CoA. The members of this CD are widely found in all three forms of life.	1.25289e-86
NC_019678.1|WP_015121813.1|7448422_7449394_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|187539	cd05228, AR_FR_like_1_SDR_e, uncharacterized subgroup of aldehyde reductase and flavonoid reductase related proteins, extended (e) SDRs. This subgroup contains proteins of unknown function related to aldehyde reductase and flavonoid reductase of the extended SDR-type. Aldehyde reductase I (aka carbonyl reductase) is an NADP-binding SDR; it has an NADP-binding motif consensus that is slightly different from the canonical SDR form and lacks the Asn of the extended SDR active site tetrad. Aldehyde reductase I catalyzes the NADP-dependent reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (R)-4-chloro-3-hydroxybutanoate. The related flavonoid reductases act in the NADP-dependent reduction of flavonoids, ketone-containing plant secondary metabolites. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.22802e-88

Protein sequences

>NC_019678.1|WP_015121814.1|7449595_7450105_+|sterol-desaturase-family-protein
MNPVLLSASTAIICFLIAFVLASLVEYWLHRLMHVNRKIGERHRDHHRRNEGQGVVWEFRDYVVGSSLVMVVMFFFSWDAGLGWFLGSLSYAAFSAYAHQLQHENPTKCFWMEMPVHYVHHKYGMWEHNFGLAVDWWDHVFGTYKPVEEWMGEKEIALSQRGYLQLKWW
>NC_019678.1|WP_015121813.1|7448422_7449394_+|NAD-dependent-epimerase/dehydratase-family-protein
MKALVTGANGFTGSHLVKALVQRGDSVVGLVRKSSDLSRLEDTEIQLVTGDITDRKALREAMQGVDTVFHTAAFVELGLVDAEKMERVNVEGTQAVLEIAKEMEISKMVYCSTIGIYGDTQGEVIDETFERTQEDFSSAYDSTKYEAQQLVDNYAVIGLPVVSVMPSGIYGPDDPHFGPVFKLFLQGKLKLWVGGDRITGIVHVDDLVNAMILAAEKGERGEHFIISAGELPLREMFEIISEQTGVSTPAEVPQPIARLVGNVLDPIGKVLSWNPPIGKERIHYIYDRCVRVDASKAREKLGWEPRSVPEILEEIVTHLQTQN
>NC_019678.1|WP_015121812.1|7447280_7448426_+|hypothetical-protein
MVTEVQKYTVSPVTTEAQREMFLDVPFKVYKNYPNWVPPIRSSIARQLASQNNPFLEYGEFQQFIAVSQKNGEPLGRIVAIINRRLIESESKNVGLFGYFECIEDFEVASGLLDTASQWLRDKGMNFVRGPINLSTHNSCLFLVDNFDEPPIMMTPYNPPYYPEFMEKAGYYKGNDAYAYDFPLDLILDPKFEKGYRIACKSGITFRPLRTKGEGFEQDCRSLYELFNSTFANNYSSTPRALEEFMDEAKELQSLVDPDVFPIAEHNGKMIGCWMGLPDYNIALKHVGGKLNWLGILKFLWYRRQIDQGRVIVICSLPEYRRKMVPLGLIYLGMQGGIKKGKPYKKAELSFVWEDNSPSRKLVEAAGGKIYKTYRIYEKAL
>NC_019678.1|WP_015121811.1|7445640_7446927_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MEVVEEYMQGLYQSGLYPDKFICHQKHGNFVEVENPDDGKRYKLLTFCTNDVLGLVQSEEVRQAAIDAILQYGTSNSSCSVLSGRIDLHRQLEQEISAFKHLPHTHLFLNAWMAMQALIDGFCHLAINLPGFRNTRETLILTDVLNHGCILSAVTNASNRSGKMFSHSPDVRVKAYRHCDVNDLARKLRRYAKPNDRIMVVSDAVFSMDGDIAPLPEMLDVLENYPGSVIVMDEAHASGAIGLKGGGVYDHFGITPQQVLDRGMVPLIMTTFSKFAASAGAAISSHSREMIDLLDVSPTSIGTISLPAPTTAAALESIRQVRQNPELVETLQANTRYLRARLIEHDFAAIGETNVIPVLVPPELNPKQFCRHLMEHHGIWVSAIWFIAKPRLRITANALHTKEDMDKLVNALVETRELLYKPATIATA
>NC_019678.1|WP_015121810.1|7444405_7445530_+|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha
MEIAPILRGQTVQNRVREVGINPNYWYPATWASELKPSQVLPVVIWNSAIALYRSQDGQVHAIEDACPHKGVALHKGKVTGENLACPYHGWEFNGNGICTNIPYFPKDQKLPCAKARSYAVREKYNIVWIFPGAVEDSEKVELPSVPEYDDPNWLAIPIPGEFKAHFSICNENTMDVFHGYLHENLQGWFDPQLLSLKASEESVFAQYRVSYQGWMTKFFGFSEQGNEVTTRTVTIKYNYPHYHSSLEGMSSLYLMRQPVGAQLTKSFSLLFIKIRLPQWFVKPLQKPITKIIWRFILKSFLDQDTEMIESEQRNYLANPQRRYVEINPAIIALQRVIVGQYEKFVQQSKKLSNGNNGNYASSTARMNSNLTSS
>NC_019678.1|WP_015121809.1|7442914_7443055_-|hypothetical-protein
MYTLLEHDIDYRQIVENVIEGKVADYAAANYKENSSKINLCLFKDR
>NC_019678.1|WP_015121808.1|7441882_7442716_-|fatty-acid-desaturase
MTTNLSPASLPQLNPPSPRLKVIIFTVILHLAVLLAFLPSNFSWAAVGVAVLLHWMTIGLGIAFGFHRLATHRSLQVPKWLEYFLILCGTLALQGGVFGWVGYHRVHHLHSDEQGDPHTPNEGFWWSHIGWLMHTVPARPELPRMTKDIADDQFYRFCHRYYIELQVALGVVLYLLGGWSFVVWGIFVRLFVGIHSTMFVNSVCHTIGYRNHDSGDRSTNCWWVALLTFGEGWHNNHHAFQYSARHGLQWWEIDMTWMTIRLLQFLGLATNVKLPQK
>NC_019678.1|WP_015121807.1|7440406_7441705_-|methyltransferase-domain-containing-protein
MTQTQAPNLQKTQDKISASSQNWSNILSKLPSGERYLYQLFTLIKEGNLTVINPFGTAFHFGEESSEPLILKVYNPDTYDRALAFGALGFCEAYMEGWWDEENDKLAEMIGLLFRNNVYSKASQRVTIPLLIKVLTQRLRTVPTNIQNSRKNVQHHYDVGNDFYQYFLDPTMTYSCGYQMKETDTLEQMQLQKYELICKKLALQPGESLIDIGCGWGGMLIYAAENYGISGTGITLSLEQAALAKQRIEQKGLSDKIEIKIADYREIKGQYDKFVSIGMFEHVGKDSFTTFMHKASELLTPDGVGLLHTIATQGKERLGAWVAKYIFPGGYLPQLHELTQELWAAKLTVAHCENLKPHYAETLRHWAENFTENRDKIASLGATYDERFCRMWYLYLQSSETSFRYGSLGVYQLLFFKGKPWRLDIPLNFSMK
>NC_019678.1|WP_015121806.1|7438442_7439648_-|MFS-transporter
MSTSLLTNETRKQIPILLVLLACGSLTTMTGSVVAPVMPEVKDQLAIDPRWSGMLVSMHCLTIFLFSPICGILADRIGKAKVLIPSLICYAIFGTAGALANGFTPLLISRALLGAASGGIAAASIGILSSMYEGEKRTRILGYTTSALAIASIIFPIVGGLIGSYNWRFTFGMYSLGLPAALLAYILLPRGKRKGSSSINLTQQKDRLIASLKAPSTITLFIALALTSAIFYVVIIYAPLHFKQSIGADTVVNGAILASRAIGAAVISAVGASKLAKRLGSAKAIALGFTLMAATLITIPFLKEIYLILPTAIIFGMGFGIVMPNLYDALSKSTPKEVRSSILAIGTGASNLGQFFSPILLGPVWKNAGIGVFFVGAGVALVTSFLSIQQGKALETTKYGK
>NC_019678.1|WP_015121805.1|7437013_7438261_-|CapA-family-protein
MNKFFKIALISTIIFFVGSPLTAIAQSQSQITLLAGGDVEWSRMAKESLFHREIIRYNLDFASKQEEARYPFQKIKPVLEDADISFVNLETPLSDTANKNGAFLAPTAFATGLKSAGIDVVSTANNHALDAGVAGLKDTLTSLSQVGLPAVGSGDNLASARLPYIFEKNGIRLGFLAYTMSENSGDSSYAKPNRAGVMPTDLSLIREDIQKLRSKVDYIILSFHWGLNDSEKPPFWVRNLARKSIDSGADIILGHHPHFPQGIEIYKNKPIIYCLGNFIFGHNHPYWTDNFLAKFILTPSQIKSIEILPIAGENQYLAQPFLLAGKTSQNLLKDVSNKSLALKTKMEIVGDIGVINPATAAMPKNEIDDLIYDLMLPKPLWQLLLALSAVGIVLTFIIRFGLSRFSRKRRRFARR
>NC_019678.1|WP_015121815.1|7452167_7453079_-|ChaN-family-lipoprotein
MKKHFNRLDSPIAKLFALSVGIFFLFSCSSYAEPTTNSCAAQFSESQCVDNLEGMLADLKKADVVYLGETHDSSKDHQNQLKVIQQLYKNNKKIAIGMEMFQRPFQEVLDQYIAGKITEAELVTKSEYKERWGFDWELYAPILRFAKEKKIPVLALNTPREISRKVAKEGIEKLTDADKKWIPPVTEINLDNIPYRQMVLKAFEQHQSAGHGNSDSANRFFLAQVLWDETMADTIAQFIKANQNHQVVVLAGQGHIVYGYGIPSRVERRIKDKQFTQRSVLLSVPDINSIEKNKPVADFILDK
>NC_019678.1|WP_015121816.1|7453093_7453372_-|hypothetical-protein
MLYYLVNAIGPFLVPICFVCAWSLIILVGWSMWTAARDSVNTAKQMHQIPCSGCQYFTDDYRLKCTVNPSMANTEEAIECMDYQPKTNPMLY
>NC_019678.1|WP_015121817.1|7453498_7454488_-|chlorophyll-synthase-ChlG
MSESTQPKSETADRSAKTRQLLGMKGAASGESSPKWKIRLQLMKPITWIPLIWGVVCGAASSGNYTWQTENFLKSAACMLLAGPILAGYTQTLNEYYDREIDAVNEPYRPIPSGAIPLPQVITQIWVLMIAGLGLAVALDRWAGNEFPTISVIAVLGVLIAYIYSAPPLKLKQNGWLGGYALGASYIAFPWCTGHALFGELNWKVVVFTVVYSLAGLGIAIVNDFKSVEGDKQFGLKSLPVVFGVEKAAWICAGMIDIFQVAIAAYLIYLHQNLYAAILLLLVIPQITLQDMYFLRDPLKNDVKYQASAQPFLVLGMLVAGIALGHSAV
>NC_019678.1|WP_015121818.1|7454684_7455785_-|ArsA-family-ATPase
MSQILTFLGESSAARTKIAIASAKSLANQGKRVLLAGGAEPVLPIMLGAYLGPDPQEIGANLQAVQFQSSVLLERNWEEVKKLEAQYLKTPILKDVYGQELSILPGMDGALALNAIREYFESGKYDVIVYNGTGNINTLRMLGMPESISWYVRRFRQLFINSDLGKAISDSPFIQPLISTFLNVNPTADNFAQPTNQANNILDKGKKVLANPQQFSAFLVTTPDPIEVVSSRFLWGSAQQVGLTIGGVIVISPNGNSNVSEDFAPLQVTNIPDIKEGNWQPLVDAVPDFTAQTLLSPKPIEIDVNARQVKLFLPGFDKKQVKLTQYGPEVTIEAGDQRRNILLPPALSGKPVAGAKFQNQYLIISF
>NC_019678.1|WP_044292480.1|7455856_7456054_-|DUF2862-domain-containing-protein
MEVGQKVKVVRLRDRLSSGSTSNKLGKVGTIKDFKITDGMGVGCVVKFDDNSATWFFEDELKVVQ
>NC_019678.1|WP_015121820.1|7456416_7457274_+|ABC-transporter-permease
MRTINVFVRISSKLKRVLPINEQWWTKFDLLRTLVRRDLEARYKGSVLGNLWSLVNPLSQLLIYTYVFSIVLKVKLSLKGLEANESVSFGLWLFAGLLPWIAFSTGLVQSAGAVVNQPNLVKKVVFPLSLLPLVPIFSAFIESSLGLIMLIFFVAVFSGNLHTTLALLPLVWIPQLLLTAGLGYLAAGLTVFLRDIPQTLNVILNIWFYATPIVYPATSIPESWQSWILWLNPLAAIAEVYRDFVLVGEVKHWGELGVAFTISGIIFFIGILTYRKLRPGFADVL
>NC_019678.1|WP_015121821.1|7457314_7458388_+|GDP-mannose-4,6-dehydratase
MVRKALITGITGQDGSYLSELLLEKRYEVHGVIRRTSTFNTDRIDHIYTDPHSDNARLFLHYGDLTDGTTLRRILETVKPDEIYNLGAQSHVRVSFDSPEYTADTVGMGALRLLEALRDYQQRTGLDVRFYQAGSSEMFGKVREVPQLEETPFYPRSPYACAKVFAHWQTVNYRESYGLFACNGILFNHESPRRGETFVTRKITRAVANIVAGKQQKLYMGNIDAKRDWGYAKDYVQAMWLMLQRKQADDYVIATGETHSVREFLDIAFNYVNLDWQDYVAFDERYLRPAEVDLLVGDASKAKQELGWKQTVSFEELVKLMVEADLQVLGLVSPNGNSKFAVSDNATTRNKSRTLIA
>NC_019678.1|WP_015121822.1|7458455_7459760_+|ABC-transporter-ATP-binding-protein
MGEEVAISLKNISKCYKRYARPVDRLKEILLPGKSYAQDFWALKDINLEINQGETVGIIGQNGSGKSTLLQVIARTLTPTTGEVFVNGRVSALLELGSGFNPEFTGRQNVFFNGRILGLSKEEIAAKYDDIAAFAEIGEFIDQPVKTYSSGMFVRLAFAVAVNVNPEILIVDEALAVGDIFFQQKCFEAIKNLKDLGTSLLFVSHDSTAVYKLCQRALLIETGQILLDSKPKTVIDLYEAKLLKQKDVESEKIEVQMFSDLNNEIIKNQNSSTISTDLKEVSINVSDVYVEYVKFLDIKNKEVDVLISEHTLKIIVGLSFLKCFEDPHIGFKIRDIKGEVIFETNTYCMKESIGKVEENDFYEFCFEFQIPILAGEYSISIGVSEIGYGEGSFKRTLVYSHNVAKLKILSNKDSILWSGIVNLKPSFYKRKVSV
>NC_019678.1|WP_015121823.1|7459803_7461606_+|methyltransferase-domain-containing-protein
MFESIIKTYKSTNYNFIETANPHDPLASSFQDWVNYYKLKWSIANVLKPNSILEIGVRFGYSAVAFLEAYPSAKYVGIDLDTDFFGGVKGGINWAKKITKPFNTEFIVANTQTMKLFPGDVYDLIHVDGQQDGDGSLHDLELAIKQGKYILMDGYLWTSQNFLAANDFLLKNADLLDWYGVIPGYAGELLIKVSENYLNQTHKLETTASSSLDIRQTYTKDYFTQDCGGFEAYKKNKGKILQDPRIIAVANISGYKKSGRVLDLGCGRGELSYYFASQGFSVTSIDYSKNAIELAQKCFDGDEQLRDNVEFICNDVCSVELSGKYDLAVASDIIEHLNFTEVDRLYQKVSQSLYRNGLFVLHTFPNSWYYKYHYPYRRKIAASVGAYLPPEPRSRYELLMHINEQSPRVLKKQLSKHFEHVCVWFGEPLNPGGSLVQHFTKAEMRASPSLFAIAAHEPINYEQIKNNLHMKILPSISNEEISLIVTKHPQVVDVNSEFMIHLEIGNYSDFVLNSYGDRPVHIAYHWMNQTAEDYIIFDGERTKIIPSLNKSVQKIKYKAKVKALSEKGNYLLRVTLVQEGVRWFDTQSTNLYQDVYIEIQ
>NC_019678.1|WP_015121824.1|7461673_7463092_+|methyltransferase-domain-containing-protein
MIESNNPEINVEKLMQKIREEVDKGKNQNQQPLAAVNSNAGKLNFNFNYIEALIQNAEKRAFVRTKLPEKLNRFSFPLSNKIKQYGLKIFNFIFRDQREVNFNLISALKQSIVINRQLIKEIENLRLQLNDYSSNNENTIQSLNSQIDELKTGISHVDKQFNELDSGISQLDELSKKLSTDINQINRFDQRLNEINTDVKSLKDSYLHNDIFIKNDLGQQKRLITMLLEQARQRLPETLNQEESQYVVKQEKHLTDAFYVAFEDKFRGTRENILNRLKVYLPLIEDAKIGTPEKPILDVGCGRGEWLELLRESGYTARGIDINKVMIEQCLSRGLDVIESDVILYLQSFEDNSLGAISGFHIIEHLPFETLMTLFAEAIRVIKPGGLIIFETPNPENVIVGSYSFYSDPTHRNPLPSPTIKFVAEYYGLKQVKIMNLNPYPKEFMFSGSDVEKCFEKYFYGAQDYAVIGFKS

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_019678_7	7.2|2244556|18|NC_019678|CRT	2244556-2244573	18	NC_019678.1	3036488-3036505	1	0.944
NC_019678_21	21.2|4614650|33|NC_019678|CRT	4614650-4614682	33	NC_019678.1	4614542-4614574	1	0.97
NC_019678_21	21.4|4614758|33|NC_019678|CRT	4614758-4614790	33	NC_019678.1	4614542-4614574	2	0.939

1. spacer 7.2|2244556|18|NC_019678|CRT matches to position: 3036488-3036505, mismatch: 1, identity: 0.944

actccagaacaaatgcag	CRISPR spacer
actccagaacaaattcag	Protospacer
************** ***

2. spacer 21.2|4614650|33|NC_019678|CRT matches to position: 4614542-4614574, mismatch: 1, identity: 0.97

gccttgaaggtggtaacggtagagatgttttag	CRISPR spacer
gccttgaaggtggtaacggtagagatgttctag	Protospacer
*****************************.***

3. spacer 21.4|4614758|33|NC_019678|CRT matches to position: 4614542-4614574, mismatch: 2, identity: 0.939

gccttgaaggtggtaacggtaaagacgttctag	CRISPR spacer
gccttgaaggtggtaacggtagagatgttctag	Protospacer
*********************.***.*******

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_019678_4	4.43|290017|35|NC_019678|CRISPRCasFinder,CRT	290017-290051	35	CP003185	Thermoanaerobacterium saccharolyticum JW/SL-YS485 plasmid pMU3262, complete genome	38962-38996	5	0.857
NC_019678_4	4.43|290017|35|NC_019678|CRISPRCasFinder,CRT	290017-290051	35	NC_019956	Thermoanaerobacterium thermosaccharolyticum M0795 plasmid pTHETHE01, complete sequence	99191-99225	5	0.857
NC_019678_4	4.57|289729|35|NC_019678|PILER-CR	289729-289763	35	NC_011265	Borrelia duttonii Ly plasmid pl27, complete sequence	12665-12699	6	0.829
NC_019678_7	7.3|2244592|30|NC_019678|CRT	2244592-2244621	30	MG962376	Mycobacterium phage Thumb, complete genome	18258-18287	6	0.8
NC_019678_7	7.3|2244592|30|NC_019678|CRT	2244592-2244621	30	MN855712	Bacteriophage sp. isolate 164, complete genome	2104-2133	6	0.8
NC_019678_7	7.3|2244592|30|NC_019678|CRT	2244592-2244621	30	KJ567046	Mycobacterium phage Damien, complete genome	18258-18287	6	0.8
NC_019678_7	7.3|2244592|30|NC_019678|CRT	2244592-2244621	30	MN010756	Mycobacterium phage Phreeze, complete genome	18258-18287	6	0.8
NC_019678_7	7.3|2244592|30|NC_019678|CRT	2244592-2244621	30	NC_023578	Mycobacterium phage Oaker, complete genome	18515-18544	6	0.8
NC_019678_7	7.3|2244592|30|NC_019678|CRT	2244592-2244621	30	MT521996	Mycobacterium phage Beckerton, complete genome	18795-18824	6	0.8
NC_019678_7	7.3|2244592|30|NC_019678|CRT	2244592-2244621	30	MH509445	Mycobacterium phage Cborch11, complete genome	18257-18286	6	0.8
NC_019678_7	7.3|2244592|30|NC_019678|CRT	2244592-2244621	30	NC_011292	Mycobacterium phage Konstantine, complete genome	19459-19488	6	0.8
NC_019678_21	21.1|4614596|33|NC_019678|CRT	4614596-4614628	33	NZ_CP035386	Enterobacter hormaechei strain S11_16 plasmid unnamed1, complete sequence	5034-5066	6	0.818
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	MK448905	Streptococcus phage Javan318, complete genome	26327-26360	7	0.794
NC_019678_4	4.17|288149|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288149-288182	34	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	94927-94960	7	0.794
NC_019678_4	4.39|289730|34|NC_019678|CRISPRCasFinder,CRT	289730-289763	34	NZ_CP028875	Borreliella bavariensis PBi plasmid lp28-4_cp32-1, complete sequence	36209-36242	7	0.794
NC_019678_4	4.39|289730|34|NC_019678|CRISPRCasFinder,CRT	289730-289763	34	NZ_CP016890	Pantoea agglomerans strain C410P1 plasmid unnamed1, complete sequence	56141-56174	7	0.794
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	MT968995	Escherichia phage vB_EcoM_WL-3, complete genome	6747-6780	7	0.794
NC_019678_4	4.57|289729|35|NC_019678|PILER-CR	289729-289763	35	NZ_CP028875	Borreliella bavariensis PBi plasmid lp28-4_cp32-1, complete sequence	36209-36243	7	0.8
NC_019678_7	7.3|2244592|30|NC_019678|CRT	2244592-2244621	30	NZ_CP021153	Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-1, complete sequence	38348-38377	7	0.767
NC_019678_7	7.3|2244592|30|NC_019678|CRT	2244592-2244621	30	NZ_CP035460	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-2, complete sequence	41992-42021	7	0.767
NC_019678_26	26.23|6182758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6182758-6182790	33	NZ_CP012367	Enterococcus durans strain KLDS 6.0933 plasmid unnamed 1, complete sequence	26783-26815	7	0.788
NC_019678_26	26.23|6182758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6182758-6182790	33	NZ_CP012385	Enterococcus durans strain KLDS 6.0930 plasmid unnamed 1, complete sequence	71668-71700	7	0.788
NC_019678_26	26.23|6182758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6182758-6182790	33	NZ_CP016847	Carnobacterium maltaromaticum strain TMW 2.1581 plasmid pL21581-3, complete sequence	42434-42466	7	0.788
NC_019678_26	26.23|6182758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6182758-6182790	33	NZ_CP042840	Enterococcus sp. DA9 plasmid unnamed4	82704-82736	7	0.788
NC_019678_26	26.51|6184758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6184758-6184790	33	NZ_CP022299	Acinetobacter johnsonii strain IC001 plasmid pIC001A, complete sequence	82037-82069	7	0.788
NC_019678_26	26.62|6185551|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR	6185551-6185583	33	NZ_CP047429	Spiroplasma citri strain BLH-13 plasmid pSciBLH13-1, complete sequence	43598-43630	7	0.788
NC_019678_26	26.74|6186409|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR	6186409-6186441	33	MH319748	Marine virus AG-345-E15 Ga0172270_18 genomic sequence	3252-3284	7	0.788
NC_019678_4	4.10|287648|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	287648-287682	35	NZ_CP041231	Bacteroides xylanisolvens strain H207 plasmid unnamed1, complete sequence	26446-26480	8	0.771
NC_019678_4	4.10|287648|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	287648-287682	35	NZ_CP041397	Bacteroides ovatus strain 3725 D1 iv plasmid unnamed2, complete sequence	18964-18998	8	0.771
NC_019678_4	4.10|287648|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	287648-287682	35	NZ_CP054001	Bacteroides fragilis strain FDAARGOS_763 plasmid unnamed1, complete sequence	39651-39685	8	0.771
NC_019678_4	4.10|287648|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	287648-287682	35	NZ_CP032820	Butyricimonas faecalis strain H184 plasmid unnamed, complete sequence	26359-26393	8	0.771
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	KX550065	Streptococcus phage SpGS-1, complete genome	24872-24905	8	0.765
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	KY065501	Streptococcus phage IPP65, complete genome	24426-24459	8	0.765
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	MN693681	Marine virus AFVG_250M138, complete genome	5471-5504	8	0.765
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NC_019521	Sphingomonas phage PAU, complete genome	214909-214942	8	0.765
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	MN693885	Marine virus AFVG_250M83, complete genome	32741-32774	8	0.765
NC_019678_4	4.24|288653|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288653-288687	35	NZ_CP021876	Enterococcus wangshanyuanii strain MN05 plasmid unnamed3	168571-168605	8	0.771
NC_019678_4	4.39|289730|34|NC_019678|CRISPRCasFinder,CRT	289730-289763	34	NC_011265	Borrelia duttonii Ly plasmid pl27, complete sequence	12665-12698	8	0.765
NC_019678_4	4.39|289730|34|NC_019678|CRISPRCasFinder,CRT	289730-289763	34	NZ_CP017026	Campylobacter coli plasmid pCC14983A-1, complete sequence	138064-138097	8	0.765
NC_019678_4	4.39|289730|34|NC_019678|CRISPRCasFinder,CRT	289730-289763	34	NZ_CP017026	Campylobacter coli plasmid pCC14983A-1, complete sequence	139158-139191	8	0.765
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	NC_017239	Borreliella afzelii PKo plasmid lp28-2, complete sequence	20018-20051	8	0.765
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	NZ_CP009063	Borreliella afzelii K78 plasmid lp28-2, complete sequence	6597-6630	8	0.765
NC_019678_4	4.57|289729|35|NC_019678|PILER-CR	289729-289763	35	NZ_CP016890	Pantoea agglomerans strain C410P1 plasmid unnamed1, complete sequence	56140-56174	8	0.771
NC_019678_7	7.1|2244508|30|NC_019678|CRT	2244508-2244537	30	MH616673	Microviridae sp. isolate ctce728, complete genome	752-781	8	0.733
NC_019678_21	21.1|4614596|33|NC_019678|CRT	4614596-4614628	33	LC520287	Escherichia coli HP129 plasmid pHP129 DNA, complete sequence	124744-124776	8	0.758
NC_019678_21	21.1|4614596|33|NC_019678|CRT	4614596-4614628	33	NZ_CP020508	Serratia marcescens strain BWH-35 plasmid unnamed, complete sequence	126180-126212	8	0.758
NC_019678_21	21.1|4614596|33|NC_019678|CRT	4614596-4614628	33	NZ_CP020506	Serratia marcescens strain 95 plasmid unnamed1, complete sequence	63010-63042	8	0.758
NC_019678_21	21.4|4614758|33|NC_019678|CRT	4614758-4614790	33	NZ_CP024200	Thalassospira marina strain CSC3H3 plasmid pCSC3H3, complete sequence	93166-93198	8	0.758
NC_019678_21	21.4|4614758|33|NC_019678|CRT	4614758-4614790	33	NZ_KU896918	Lactobacillus plantarum strain A-1 plasmid pA1_ASM1, complete sequence	11080-11112	8	0.758
NC_019678_26	26.23|6182758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6182758-6182790	33	NZ_CP053834	Arcobacter cloacae strain LMG 26153 plasmid pACLO, complete sequence	78472-78504	8	0.758
NC_019678_26	26.70|6186123|31|NC_019678|CRISPRCasFinder,CRT,PILER-CR	6186123-6186153	31	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	595867-595897	8	0.742
NC_019678_26	26.70|6186123|31|NC_019678|CRISPRCasFinder,CRT,PILER-CR	6186123-6186153	31	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	1412106-1412136	8	0.742
NC_019678_26	26.70|6186123|31|NC_019678|CRISPRCasFinder,CRT,PILER-CR	6186123-6186153	31	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	523606-523636	8	0.742
NC_019678_26	26.70|6186123|31|NC_019678|CRISPRCasFinder,CRT,PILER-CR	6186123-6186153	31	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	720265-720295	8	0.742
NC_019678_26	26.74|6186409|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR	6186409-6186441	33	HQ316603	Cyanophage S-SSM6b genomic sequence	165752-165784	8	0.758
NC_019678_26	26.74|6186409|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR	6186409-6186441	33	NC_020875	Cyanophage S-SSM4 genomic sequence	98845-98877	8	0.758
NC_019678_26	26.81|6186915|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR	6186915-6186949	35	NZ_CP015094	Pelagibaca abyssi strain JLT2014 plasmid pPABY6, complete sequence	54759-54793	8	0.771
NC_019678_26	26.85|6187204|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR	6187204-6187236	33	NC_001949	Lactococcus lactis DPC3147 plasmid pMRC01, complete sequence	17133-17165	8	0.758
NC_019678_33	33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6752329-6752363	35	MT074137	Bacteroides phage DAC16, complete genome	46495-46529	8	0.771
NC_019678_33	33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6752329-6752363	35	MT074142	Bacteroides phage DAC23, complete genome	46591-46625	8	0.771
NC_019678_33	33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6752329-6752363	35	MT074141	Bacteroides phage DAC22, complete genome	49138-49172	8	0.771
NC_019678_33	33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6752329-6752363	35	MT074139	Bacteroides phage DAC19, complete genome	49050-49084	8	0.771
NC_019678_33	33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6752329-6752363	35	MT074140	Bacteroides phage DAC20, complete genome	49050-49084	8	0.771
NC_019678_38	38.4|7450592|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	7450592-7450624	33	NC_016821	Leuconostoc mesenteroides subsp. mesenteroides J18 plasmid pKLE03, complete sequence	967-999	8	0.758
NC_019678_38	38.4|7450592|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	7450592-7450624	33	NZ_CP014603	Leuconostoc mesenteroides subsp. mesenteroides strain DRC0211 plasmid pDSK3, complete sequence	19649-19681	8	0.758
NC_019678_38	38.4|7450592|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	7450592-7450624	33	NZ_CP014603	Leuconostoc mesenteroides subsp. mesenteroides strain DRC0211 plasmid pDSK3, complete sequence	44197-44229	8	0.758
NC_019678_38	38.4|7450592|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	7450592-7450624	33	MK415406	Phage FAKO27_000238F, complete genome	54194-54226	8	0.758
NC_019678_38	38.4|7450592|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	7450592-7450624	33	KT070867	Bacillus phage PBC2, complete genome	28130-28162	8	0.758
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NC_015598	Lactobacillus kefiranofaciens ZW3 plasmid pWW1, complete sequence	187222-187255	9	0.735
NC_019678_4	4.2|287070|32|NC_019678|PILER-CR,CRISPRCasFinder,CRT	287070-287101	32	KY065492	Streptococcus phage IPP54, complete genome	6280-6311	9	0.719
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	MK496764	Capybara microvirus Cap3_SP_319, complete genome	3429-3462	9	0.735
NC_019678_4	4.18|288220|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288220-288253	34	NZ_CP038016	Paenisporosarcina antarctica strain CGMCC 1.6503 plasmid unnamed, complete sequence	27404-27437	9	0.735
NC_019678_4	4.31|289154|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	289154-289187	34	MN830254	Lactobacillus phage JNU_P2, complete genome	36147-36180	9	0.735
NC_019678_4	4.31|289154|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	289154-289187	34	MN830255	Lactobacillus phage JNU_P4, complete genome	22670-22703	9	0.735
NC_019678_4	4.39|289730|34|NC_019678|CRISPRCasFinder,CRT	289730-289763	34	NZ_CP027853	Plesiomonas shigelloides strain MS-17-188 plasmid pPS-MS-17-188-1, complete sequence	392155-392188	9	0.735
NC_019678_4	4.39|289730|34|NC_019678|CRISPRCasFinder,CRT	289730-289763	34	KU594606	Cyanophage S-RIM32 isolate RW_108_0702, complete genome	5357-5390	9	0.735
NC_019678_4	4.43|290017|35|NC_019678|CRISPRCasFinder,CRT	290017-290051	35	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	897903-897937	9	0.743
NC_019678_4	4.45|290160|34|NC_019678|CRISPRCasFinder,CRT	290160-290193	34	NZ_CP039965	Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence	635135-635168	9	0.735
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	MN241318	Enterococcus phage PEf771, complete genome	8056-8089	9	0.735
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	MN027503	Enterococcus phage vB_OCPT_Ben, complete genome	37807-37840	9	0.735
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	CAJDKA010000002	Enterococcus phage 163 genome assembly, contig: phage163-genome, whole genome shotgun sequence	61341-61374	9	0.735
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	MT856905	Enterococcus phage vB_EfaM_A2, complete genome	113047-113080	9	0.735
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	MW004544	Enterococcus phage EFGrKN, complete genome	112030-112063	9	0.735
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	NC_029009	Enterococcus phage EFDG1, complete genome	112140-112173	9	0.735
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	MH880817	Enterococcus phage EfV12-phi1, complete genome	116506-116539	9	0.735
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	MN693785	Marine virus AFVG_250M536, complete genome	16809-16842	9	0.735
NC_019678_4	4.54|290810|34|NC_019678|CRISPRCasFinder,CRT	290810-290843	34	MT932329	Campylobacter phage F379, complete genome	176450-176483	9	0.735
NC_019678_4	4.54|290810|34|NC_019678|CRISPRCasFinder,CRT	290810-290843	34	MK408758	Campylobacter phage CP20, complete genome	20866-20899	9	0.735
NC_019678_4	4.54|290810|34|NC_019678|CRISPRCasFinder,CRT	290810-290843	34	HM246721	Campylobacter phage vB_CcoM-IBB_35 clone Contig2, complete sequence	24474-24507	9	0.735
NC_019678_4	4.54|290810|34|NC_019678|CRISPRCasFinder,CRT	290810-290843	34	FN667788	Campylobacter phage CP220, complete genome	19421-19454	9	0.735
NC_019678_4	4.54|290810|34|NC_019678|CRISPRCasFinder,CRT	290810-290843	34	FN667789	Campylobacter phage CPt10, complete genome	20866-20899	9	0.735
NC_019678_7	7.3|2244592|30|NC_019678|CRT	2244592-2244621	30	KP671755	Vibrio phage ValKK3, complete genome	72495-72524	9	0.7
NC_019678_7	7.3|2244592|30|NC_019678|CRT	2244592-2244621	30	MF042360	Pseudomonas phage Phabio, complete genome	114023-114052	9	0.7
NC_019678_7	7.3|2244592|30|NC_019678|CRT	2244592-2244621	30	KT919972	Vibrio phage phi-Grn1, complete genome	168812-168841	9	0.7
NC_019678_21	21.1|4614596|33|NC_019678|CRT	4614596-4614628	33	NC_011282	Klebsiella variicola strain 342 plasmid pKP187, complete sequence	91811-91843	9	0.727
NC_019678_21	21.1|4614596|33|NC_019678|CRT	4614596-4614628	33	NZ_CP044049	Klebsiella variicola strain FDAARGOS_627 plasmid unnamed1, complete sequence	155488-155520	9	0.727
NC_019678_21	21.2|4614650|33|NC_019678|CRT	4614650-4614682	33	NZ_CP024200	Thalassospira marina strain CSC3H3 plasmid pCSC3H3, complete sequence	93166-93198	9	0.727
NC_019678_21	21.3|4614704|33|NC_019678|CRT	4614704-4614736	33	NC_011282	Klebsiella variicola strain 342 plasmid pKP187, complete sequence	91811-91843	9	0.727
NC_019678_21	21.3|4614704|33|NC_019678|CRT	4614704-4614736	33	NZ_CP044049	Klebsiella variicola strain FDAARGOS_627 plasmid unnamed1, complete sequence	155488-155520	9	0.727
NC_019678_21	21.5|4614812|33|NC_019678|CRT	4614812-4614844	33	NC_011282	Klebsiella variicola strain 342 plasmid pKP187, complete sequence	91811-91843	9	0.727
NC_019678_21	21.5|4614812|33|NC_019678|CRT	4614812-4614844	33	NZ_CP044049	Klebsiella variicola strain FDAARGOS_627 plasmid unnamed1, complete sequence	155488-155520	9	0.727
NC_019678_26	26.17|6182328|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6182328-6182362	35	GU233956	Bacillus phage 11143, partial sequence	14958-14992	9	0.743
NC_019678_26	26.23|6182758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6182758-6182790	33	NZ_CP049807	Acinetobacter pittii strain A1254 plasmid pA1254_1, complete sequence	11785-11817	9	0.727
NC_019678_26	26.51|6184758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6184758-6184790	33	MT074137	Bacteroides phage DAC16, complete genome	46769-46801	9	0.727
NC_019678_26	26.51|6184758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6184758-6184790	33	MT074142	Bacteroides phage DAC23, complete genome	46865-46897	9	0.727
NC_019678_26	26.51|6184758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6184758-6184790	33	MT074146	Bacteroides phage SJC03, complete genome	41808-41840	9	0.727
NC_019678_26	26.74|6186409|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR	6186409-6186441	33	MF001361	Enterococcus phage EF5, partial genome	69349-69381	9	0.727
NC_019678_26	26.74|6186409|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR	6186409-6186441	33	MF001358	Enterococcus phage EF1, partial genome	47965-47997	9	0.727
NC_019678_26	26.74|6186409|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR	6186409-6186441	33	NZ_CP013927	Alteromonas stellipolaris strain LMG 21861 plasmid pASTE61-200, complete sequence	103415-103447	9	0.727
NC_019678_33	33.13|6752258|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6752258-6752291	34	NC_007110	Rickettsia felis URRWXCal2 plasmid pRF, complete sequence	962-995	9	0.735
NC_019678_33	33.13|6752258|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6752258-6752291	34	NC_007111	Rickettsia felis URRWXCal2 plasmid pRFdelta, complete sequence	962-995	9	0.735
NC_019678_33	33.13|6752258|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6752258-6752291	34	NC_019229	Rickettsia felis plasmid pRF, complete sequence	962-995	9	0.735
NC_019678_33	33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6752329-6752363	35	AP013489	Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C30A-MedDCM-OCT-S45-C81	2037-2071	9	0.743
NC_019678_33	33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6752329-6752363	35	MN698245	Pelagibacter phage HTVC111P, complete genome	3384-3418	9	0.743
NC_019678_33	33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6752329-6752363	35	AP013487	Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C30A-MedDCM-OCT-S33-C83	18393-18427	9	0.743
NC_019678_33	33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6752329-6752363	35	AP013488	Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C30A-MedDCM-OCT-S38-C82	682-716	9	0.743
NC_019678_33	33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6752329-6752363	35	AP013486	Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C30A-MedDCM-OCT-S29-C73	10011-10045	9	0.743
NC_019678_33	33.15|6752401|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6752401-6752433	33	NZ_CP040718	Aeromonas veronii strain HX3 plasmid pHX3, complete sequence	110464-110496	9	0.727
NC_019678_38	38.4|7450592|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	7450592-7450624	33	MK448893	Streptococcus phage Javan270, complete genome	34080-34112	9	0.727
NC_019678_4	4.7|287431|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	287431-287465	35	NZ_CP040940	Cetia pacifica strain TB6 plasmid unnamed1, complete sequence	10554-10588	10	0.714
NC_019678_4	4.7|287431|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT	287431-287465	35	CP016195	Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-1, complete sequence	260814-260848	10	0.714
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_KU525621	Bacillus anthracis strain P.NO2 plasmid pXO2, complete sequence	84957-84990	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NC_014332	Bacillus cereus biovar anthracis str. CI plasmid pCI-XO2, complete sequence	85725-85758	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NC_012577	Bacillus anthracis str. CDC 684 plasmid pX02, complete sequence	83605-83638	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP015778	Bacillus anthracis strain Tangail-1 plasmid pXO2, complete sequence	85189-85222	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP018905	Bacillus anthracis strain Tyrol 4675 plasmid pXO2, complete sequence	85518-85551	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP023003	Bacillus anthracis strain 14RA5914 plasmid pX02, complete sequence	20578-20611	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_AP019733	Bacillus anthracis strain PCr plasmid PCr-pXO2	26418-26451	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_AP018445	Bacillus anthracis strain CZC5 plasmid pXO2, complete sequence	85161-85194	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP029325	Bacillus anthracis strain 17OD930 plasmid pXO2, complete sequence	73459-73492	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NC_012655	Bacillus anthracis str. A0248 plasmid pXO2, complete sequence	86232-86265	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NC_007323	Bacillus anthracis str. 'Ames Ancestor' plasmid pXO2, complete sequence	85189-85222	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP024976	Escherichia coli strain CV839-15 plasmid pCV839-15-p2, complete sequence	108371-108404	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP010854	Bacillus anthracis strain A1144 plasmid pXO2, complete sequence	85342-85375	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP007617	Bacillus anthracis strain 2000031021 plasmid pXO2, complete sequence	60749-60782	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP008848	Bacillus anthracis strain HYU01 plasmid pX02, complete sequence	85093-85126	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP006744	Bacillus anthracis str. SVA11 plasmid pXO2, complete sequence	85119-85152	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_AP014835	Bacillus anthracis strain Shikan-NIID plasmid pXO2	85179-85212	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP029807	Bacillus anthracis strain London_499 plasmid pX02, complete sequence	85318-85351	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NC_002146	Bacillus anthracis plasmid pXO2, complete sequence	85663-85696	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NC_017727	Bacillus anthracis str. H9401 plasmid BAP2, complete sequence	85176-85209	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP009314	Bacillus anthracis str. Turkey32 strain 35 plasmid unnamed, complete sequence	92014-92047	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP014178	Bacillus anthracis strain Stendal plasmid pXO2, complete sequence	85189-85222	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP009475	Bacillus anthracis strain Pasteur plasmid pXO2, complete sequence	12955-12988	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP009900	Bacillus anthracis strain 2002013094 plasmid pXO2, complete sequence	70204-70237	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP009339	Bacillus anthracis strain Ohio ACB plasmid 2, complete sequence	9657-9690	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP009695	Bacillus anthracis strain RA3 plasmid pXO2, complete sequence	18619-18652	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP009462	Bacillus anthracis strain SK-102 plasmid pXO2, complete sequence	17894-17927	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP009698	Bacillus anthracis strain BA1035 plasmid pXO2, complete sequence	82371-82404	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP009542	Bacillus anthracis strain BA1015 plasmid pXO2, complete sequence	44167-44200	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP010320	Bacillus anthracis strain Canadian Bison isolate A0369 plasmid 2, complete sequence	15348-15381	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP009329	Bacillus anthracis strain K3 plasmid 2, complete sequence	24633-24666	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP009326	Bacillus anthracis strain Vollum 1B plasmid 2, complete sequence	44117-44150	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP009979	Bacillus anthracis strain Ames isolate BACI008 plasmid unnamed2, complete sequence	83117-83150	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP001972	Bacillus anthracis str. A16 plasmid pXO2, complete sequence	85192-85225	10	0.706
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_CP047133	Bacillus anthracis str. BF1 plasmid pXO2, complete sequence	85103-85136	10	0.706
NC_019678_4	4.18|288220|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288220-288253	34	NZ_CP008877	Terribacillus goriensis strain MP602 plasmid pT1, complete sequence	6164-6197	10	0.706
NC_019678_4	4.21|288435|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288435-288468	34	NC_024792	Bacillus phage Bobb, complete genome	45731-45764	10	0.706
NC_019678_4	4.33|289296|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	289296-289329	34	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	311432-311465	10	0.706
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	MN693021	Marine virus AFVG_117M32, complete genome	33997-34030	10	0.706
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	NZ_LR214994	Mycoplasma hyopneumoniae strain NCTC10127 plasmid 3	17804-17837	10	0.706
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	NZ_LR214995	Mycoplasma hyopneumoniae strain NCTC10127 plasmid 4	2691-2724	10	0.706
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	MN694380	Marine virus AFVG_250M409, complete genome	12760-12793	10	0.706
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	KY549443	Enterococcus phage EFP01, complete genome	38130-38163	10	0.706
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	MN693770	Marine virus AFVG_250M115, complete genome	28948-28981	10	0.706
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	MT909815	Enterococcus phage iF6, complete genome	111030-111063	10	0.706
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	MN694329	Marine virus AFVG_250M203, complete genome	28899-28932	10	0.706
NC_019678_4	4.57|289729|35|NC_019678|PILER-CR	289729-289763	35	NZ_CP027853	Plesiomonas shigelloides strain MS-17-188 plasmid pPS-MS-17-188-1, complete sequence	392154-392188	10	0.714
NC_019678_4	4.68|290516|35|NC_019678|PILER-CR	290516-290550	35	MN693785	Marine virus AFVG_250M536, complete genome	16809-16843	10	0.714
NC_019678_26	26.36|6183680|37|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6183680-6183716	37	NC_013160	Rippkaea orientalis PCC 8802 plasmid pP880201, complete sequence	75015-75051	10	0.73
NC_019678_26	26.41|6184047|32|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6184047-6184078	32	MN855600	Bacteriophage sp. isolate 296, complete genome	4221-4252	10	0.688
NC_019678_26	26.44|6184257|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6184257-6184290	34	CP031730	Stenotrophomonas rhizophila strain GA1 plasmid unnamed1, complete sequence	149465-149498	10	0.706
NC_019678_26	26.81|6186915|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR	6186915-6186949	35	NZ_CP051182	Thalassobius gelatinovorus strain NEB572 plasmid pAge77, complete sequence	49906-49940	10	0.714
NC_019678_33	33.15|6752401|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT	6752401-6752433	33	MN693532	Marine virus AFVG_25M340, complete genome	18218-18250	10	0.697
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_KX839207	Klebsiella pneumoniae strain KP1814 plasmid pKP1814-1, complete sequence	141140-141173	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_CP021328	Raoultella ornithinolytica strain Ro24724 plasmid pRo24724, complete sequence	355425-355458	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_CP019048	Klebsiella pneumoniae subsp. pneumoniae strain RJA166 plasmid pRJA166a, complete sequence	52372-52405	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_CP022441	Klebsiella sp. LY plasmid unnamed3, complete sequence	228210-228243	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_CP024641	Klebsiella michiganensis strain F107 plasmid unnamed1, complete sequence	24548-24581	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_CP026369	Klebsiella quasipneumoniae strain A708 plasmid pA708-1, complete sequence	118041-118074	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_CP028952	Klebsiella aerogenes strain AR_0161 plasmid unnamed, complete sequence	20606-20639	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	MN661402	Klebsiella quasipneumoniae strain KP18-31 plasmid pKP18-31-IMP,KPC, complete sequence	257788-257821	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_KY270853	Raoultella ornithinolytica strain YNKP001 plasmid pYNKP001-dfrA, complete sequence	2424-2457	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_CP025467	Klebsiella pneumoniae strain JS187 plasmid p187-1, complete sequence	194163-194196	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NC_018107	Klebsiella michiganensis E718 plasmid pKOX_R1, complete sequence	169680-169713	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	KU318421	Klebsiella pneumoniae strain KP04 plasmid pKP04VIM, complete sequence	2962-2995	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NC_023911	Raoultella planticola strain KpNDM1 plasmid pKpNDM1, complete sequence	221494-221527	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_CP025964	Klebsiella pneumoniae strain WCHKP34 plasmid pIMP4_LL34, complete sequence	137938-137971	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_CP038277	Raoultella ornithinolytica strain WLK218 plasmid pWLK-238550, complete sequence	185747-185780	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	CP027603	UNVERIFIED_ORG: Klebsiella pneumoniae strain AR_0080 plasmid unnamed, complete sequence	35508-35541	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_CP046614	Klebsiella pneumoniae strain WCGKP294 plasmid pWCGKP294-2, complete sequence	2962-2995	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_CP026014	Klebsiella variicola strain 13450 plasmid p13450-1, complete sequence	82219-82252	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_CP026019	Klebsiella pneumoniae strain 13190 plasmid p13190-1, complete sequence	240489-240522	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_MF344561	Klebsiella pneumoniae strain 11219 plasmid p11219-IMP, complete sequence	2962-2995	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_MF344566	Klebsiella pneumoniae strain A324 plasmid pA324-IMP, complete sequence	2634-2667	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_MF344565	Klebsiella pneumoniae strain 19051 plasmid p19051-IMP, complete sequence	2962-2995	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_MF344562	Klebsiella pneumoniae strain 12208 plasmid p12208-IMP, complete sequence	2961-2994	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_MF344567	Klebsiella pneumoniae strain A708 plasmid pA708-IMP, complete sequence	2962-2995	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_MF344563	Klebsiella pneumoniae strain 13190 plasmid p13190-VIM, complete sequence	2954-2987	11	0.676
NC_019678_1	1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	62999-63032	34	NZ_MF344564	Klebsiella pneumoniae strain 13450 plasmid p13450-IMP, complete sequence	2962-2995	11	0.676
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	NZ_CP038259	Acinetobacter baumannii strain 39741 plasmid pEH_gr13, complete sequence	119508-119541	11	0.676
NC_019678_4	4.68|290516|35|NC_019678|PILER-CR	290516-290550	35	MN693021	Marine virus AFVG_117M32, complete genome	33996-34030	11	0.686
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	NZ_LR214999	Mycoplasma conjunctivae strain NCTC10147 plasmid 3	20877-20910	12	0.647
NC_019678_4	4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT	288005-288038	34	LR214965	Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 11	10468-10501	12	0.647
NC_019678_4	4.50|290517|34|NC_019678|CRISPRCasFinder,CRT	290517-290550	34	NZ_CP023367	Escherichia coli strain 1428 plasmid p111, complete sequence	14575-14608	12	0.647

1. spacer 4.43|290017|35|NC_019678|CRISPRCasFinder,CRT matches to CP003185 (Thermoanaerobacterium saccharolyticum JW/SL-YS485 plasmid pMU3262, complete genome) position: , mismatch: 5, identity: 0.857

--taaaagattaatattacaatcttcaaaaattgata	CRISPR spacer
aataaaaga--aatattagaatcatcaaaaattgatg	Protospacer
  *******  ******* **** ************.

2. spacer 4.43|290017|35|NC_019678|CRISPRCasFinder,CRT matches to NC_019956 (Thermoanaerobacterium thermosaccharolyticum M0795 plasmid pTHETHE01, complete sequence) position: , mismatch: 5, identity: 0.857

--taaaagattaatattacaatcttcaaaaattgata	CRISPR spacer
aataaaaga--aatattagaatcatcaaaaattgatg	Protospacer
  *******  ******* **** ************.

3. spacer 4.57|289729|35|NC_019678|PILER-CR matches to NC_011265 (Borrelia duttonii Ly plasmid pl27, complete sequence) position: , mismatch: 6, identity: 0.829

cattg-ttgctaaatgtatttataaaatcaacagaa	CRISPR spacer
-atggatggttatatgtatttataatatcaacagaa	Protospacer
 ** * * *.** ************ **********

4. spacer 7.3|2244592|30|NC_019678|CRT matches to MG962376 (Mycobacterium phage Thumb, complete genome) position: , mismatch: 6, identity: 0.8

actccggaacaaatacgtcag-catcaccaa	CRISPR spacer
acgccggaacaaatacgtcagagaacgccg-	Protospacer
** ******************  * *.**. 

5. spacer 7.3|2244592|30|NC_019678|CRT matches to MN855712 (Bacteriophage sp. isolate 164, complete genome) position: , mismatch: 6, identity: 0.8

-actccggaacaaatacgtcagcatcaccaa	CRISPR spacer
taccacgaaa-aaatccgtcagcatcaccag	Protospacer
 **. **.** **** **************.

6. spacer 7.3|2244592|30|NC_019678|CRT matches to KJ567046 (Mycobacterium phage Damien, complete genome) position: , mismatch: 6, identity: 0.8

actccggaacaaatacgtcag-catcaccaa	CRISPR spacer
acgccggaacaaatacgtcagagaacgccg-	Protospacer
** ******************  * *.**. 

7. spacer 7.3|2244592|30|NC_019678|CRT matches to MN010756 (Mycobacterium phage Phreeze, complete genome) position: , mismatch: 6, identity: 0.8

actccggaacaaatacgtcag-catcaccaa	CRISPR spacer
acgccggaacaaatacgtcagagaacgccg-	Protospacer
** ******************  * *.**. 

8. spacer 7.3|2244592|30|NC_019678|CRT matches to NC_023578 (Mycobacterium phage Oaker, complete genome) position: , mismatch: 6, identity: 0.8

actccggaacaaatacgtcag-catcaccaa	CRISPR spacer
acgccggaacaaatacgtcagagaacgccg-	Protospacer
** ******************  * *.**. 

9. spacer 7.3|2244592|30|NC_019678|CRT matches to MT521996 (Mycobacterium phage Beckerton, complete genome) position: , mismatch: 6, identity: 0.8

actccggaacaaatacgtcag-catcaccaa	CRISPR spacer
acgccggaacaaatacgtcagagaacgccg-	Protospacer
** ******************  * *.**. 

10. spacer 7.3|2244592|30|NC_019678|CRT matches to MH509445 (Mycobacterium phage Cborch11, complete genome) position: , mismatch: 6, identity: 0.8

actccggaacaaatacgtcag-catcaccaa	CRISPR spacer
acgccggaacaaatacgtcagagaacgccg-	Protospacer
** ******************  * *.**. 

11. spacer 7.3|2244592|30|NC_019678|CRT matches to NC_011292 (Mycobacterium phage Konstantine, complete genome) position: , mismatch: 6, identity: 0.8

actccggaacaaatacgtcag-catcaccaa	CRISPR spacer
acgccggaacaaatacgtcagagaacgccg-	Protospacer
** ******************  * *.**. 

12. spacer 21.1|4614596|33|NC_019678|CRT matches to NZ_CP035386 (Enterobacter hormaechei strain S11_16 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.818

ccttaaatggcggtaatggtgccgacttacttc	CRISPR spacer
cccgaaatgtcggtaatggtgccaacttactga	Protospacer
**. ***** *************.*******  

13. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MK448905 (Streptococcus phage Javan318, complete genome) position: , mismatch: 7, identity: 0.794

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aatagcaaaagatgaagaagaacaagaaaaattg	Protospacer
** *  **** *****.***************..

14. spacer 4.17|288149|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 7, identity: 0.794

ttagcagataaaaatagtacacaagcagaaaaaa	CRISPR spacer
tttttagataaaaataatatacaagcagaaagat	Protospacer
**  .***********.**.***********.* 

15. spacer 4.39|289730|34|NC_019678|CRISPRCasFinder,CRT matches to NZ_CP028875 (Borreliella bavariensis PBi plasmid lp28-4_cp32-1, complete sequence) position: , mismatch: 7, identity: 0.794

attgttgc-taaatgtatttataaaatcaacagaa	CRISPR spacer
-ctgtgatataaatgtatttataaaatcaaaataa	Protospacer
 .*** .. ********************* * **

16. spacer 4.39|289730|34|NC_019678|CRISPRCasFinder,CRT matches to NZ_CP016890 (Pantoea agglomerans strain C410P1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.794

attgttgctaaatgtatttataaaatcaacagaa	CRISPR spacer
cttgttgctaaatgtattcatgaaattagcgaaa	Protospacer
 *****************.**.****.*.*..**

17. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to MT968995 (Escherichia phage vB_EcoM_WL-3, complete genome) position: , mismatch: 7, identity: 0.794

taagcaaatt--ctaaaagataaatttgatttttat	CRISPR spacer
--atttaattcactaaacgataaatttcatttttat	Protospacer
  * . ****  ***** ********* ********

18. spacer 4.57|289729|35|NC_019678|PILER-CR matches to NZ_CP028875 (Borreliella bavariensis PBi plasmid lp28-4_cp32-1, complete sequence) position: , mismatch: 7, identity: 0.8

cattgttgc-taaatgtatttataaaatcaacagaa	CRISPR spacer
-actgtgatataaatgtatttataaaatcaaaataa	Protospacer
 *.*** .. ********************* * **

19. spacer 7.3|2244592|30|NC_019678|CRT matches to NZ_CP021153 (Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-1, complete sequence) position: , mismatch: 7, identity: 0.767

---actccggaacaaatacgtcagcatcaccaa	CRISPR spacer
caaagt---gaacgaatacgtcagcaccaccat	Protospacer
   * *   ****.************.***** 

20. spacer 7.3|2244592|30|NC_019678|CRT matches to NZ_CP035460 (Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-2, complete sequence) position: , mismatch: 7, identity: 0.767

---actccggaacaaatacgtcagcatcaccaa	CRISPR spacer
caaagt---gaacgaatacgtcagcaccaccat	Protospacer
   * *   ****.************.***** 

21. spacer 26.23|6182758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012367 (Enterococcus durans strain KLDS 6.0933 plasmid unnamed 1, complete sequence) position: , mismatch: 7, identity: 0.788

tttacatcttgaattattttctttattcctaat--	CRISPR spacer
ctcacatcttgaatttttttcttgatt--tgattc	Protospacer
.*.************ ******* ***  *.**  

22. spacer 26.23|6182758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012385 (Enterococcus durans strain KLDS 6.0930 plasmid unnamed 1, complete sequence) position: , mismatch: 7, identity: 0.788

tttacatcttgaattattttctttattcctaat--	CRISPR spacer
ctcacatcttgaatttttttcttgatt--tgattc	Protospacer
.*.************ ******* ***  *.**  

23. spacer 26.23|6182758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016847 (Carnobacterium maltaromaticum strain TMW 2.1581 plasmid pL21581-3, complete sequence) position: , mismatch: 7, identity: 0.788

tttacatcttgaattattttctttattcctaat--	CRISPR spacer
ctcacatcttgaatttttttcttgatt--tgattc	Protospacer
.*.************ ******* ***  *.**  

24. spacer 26.23|6182758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042840 (Enterococcus sp. DA9 plasmid unnamed4) position: , mismatch: 7, identity: 0.788

tttacatcttgaattattttctttattcctaat--	CRISPR spacer
ctcacatcttgaatttttttcttgatt--tgattc	Protospacer
.*.************ ******* ***  *.**  

25. spacer 26.51|6184758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022299 (Acinetobacter johnsonii strain IC001 plasmid pIC001A, complete sequence) position: , mismatch: 7, identity: 0.788

tttaaaaattaaaatattacttaaaataatttt	CRISPR spacer
tttaaaaattaaaatatttctaaaaaataggat	Protospacer
****************** ** ****  *   *

26. spacer 26.62|6185551|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047429 (Spiroplasma citri strain BLH-13 plasmid pSciBLH13-1, complete sequence) position: , mismatch: 7, identity: 0.788

-aactaggagaaaaacttgtttcagcaactaaaa	CRISPR spacer
ttact-gaagaaaaacttgttttagaaactaatt	Protospacer
  *** *.**************.** ******  

27. spacer 26.74|6186409|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR matches to MH319748 (Marine virus AG-345-E15 Ga0172270_18 genomic sequence) position: , mismatch: 7, identity: 0.788

--gattgatcttcatagtcaaaattttcttctttc	CRISPR spacer
gtgatta--tttcatagttaaaattttcttcattg	Protospacer
  ****.  .********.************ ** 

28. spacer 4.10|287648|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041231 (Bacteroides xylanisolvens strain H207 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.771

aaatatatgaatcacaacaaacacaaaaaaggaaa	CRISPR spacer
aaacctgataatcataccaaacacaaaaaaggaac	Protospacer
***. *.  *****.* ***************** 

29. spacer 4.10|287648|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041397 (Bacteroides ovatus strain 3725 D1 iv plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.771

aaatatatgaatcacaacaaacacaaaaaaggaaa	CRISPR spacer
aaacctgataatcataccaaacacaaaaaaggaac	Protospacer
***. *.  *****.* ***************** 

30. spacer 4.10|287648|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054001 (Bacteroides fragilis strain FDAARGOS_763 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.771

aaatatatgaatcacaacaaacacaaaaaaggaaa	CRISPR spacer
aaacctgataatcataccaaacacaaaaaaggaac	Protospacer
***. *.  *****.* ***************** 

31. spacer 4.10|287648|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032820 (Butyricimonas faecalis strain H184 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.771

aaatatatgaatcacaacaaacacaaaaaaggaaa	CRISPR spacer
aaacctgataatcataccaaacacaaaaaaggaac	Protospacer
***. *.  *****.* ***************** 

32. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to KX550065 (Streptococcus phage SpGS-1, complete genome) position: , mismatch: 8, identity: 0.765

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
gacagcaaaagatgaagaagaacaagaaaaattg	Protospacer
.* *  **** *****.***************..

33. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to KY065501 (Streptococcus phage IPP65, complete genome) position: , mismatch: 8, identity: 0.765

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
gacagcaaaagatgaagaagaacaagaaaaattg	Protospacer
.* *  **** *****.***************..

34. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MN693681 (Marine virus AFVG_250M138, complete genome) position: , mismatch: 8, identity: 0.765

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
gggagaaaaatatgaataagaaaaagaaaactga	Protospacer
...* *********** ***** ******* * *

35. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NC_019521 (Sphingomonas phage PAU, complete genome) position: , mismatch: 8, identity: 0.765

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aaaataagaatatgaaacagaacaaagaactttt	Protospacer
*******.********* *******..**  *. 

36. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MN693885 (Marine virus AFVG_250M83, complete genome) position: , mismatch: 8, identity: 0.765

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
atataaaaaatatgaagaagaaaaagaaaataga	Protospacer
* *  ***********.***** *******   *

37. spacer 4.24|288653|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021876 (Enterococcus wangshanyuanii strain MN05 plasmid unnamed3) position: , mismatch: 8, identity: 0.771

ctcaatcttgaaatcttctaagcctg--agcctatga	CRISPR spacer
atcaatcttgaaatcttcatagcctggcaactcat--	Protospacer
 *****************  ******  *.*..**  

38. spacer 4.39|289730|34|NC_019678|CRISPRCasFinder,CRT matches to NC_011265 (Borrelia duttonii Ly plasmid pl27, complete sequence) position: , mismatch: 8, identity: 0.765

attgttgctaaatgtatttataaaatcaacagaa	CRISPR spacer
tggatggttatatgtatttataatatcaacagaa	Protospacer
   .* *.** ************ **********

39. spacer 4.39|289730|34|NC_019678|CRISPRCasFinder,CRT matches to NZ_CP017026 (Campylobacter coli plasmid pCC14983A-1, complete sequence) position: , mismatch: 8, identity: 0.765

--attgttgctaaatgtatttataaaatcaacagaa	CRISPR spacer
taaaagtt--taaatctatttataaaatcaatagtt	Protospacer
  *  ***  ***** ***************.**  

40. spacer 4.39|289730|34|NC_019678|CRISPRCasFinder,CRT matches to NZ_CP017026 (Campylobacter coli plasmid pCC14983A-1, complete sequence) position: , mismatch: 8, identity: 0.765

--attgttgctaaatgtatttataaaatcaacagaa	CRISPR spacer
taaaagtt--taaatctatttataaaatcaatagtt	Protospacer
  *  ***  ***** ***************.**  

41. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to NC_017239 (Borreliella afzelii PKo plasmid lp28-2, complete sequence) position: , mismatch: 8, identity: 0.765

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
tcaagaaattcttaaaaataaatttgattataaa	Protospacer
* *. ******* ***.************ * * 

42. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to NZ_CP009063 (Borreliella afzelii K78 plasmid lp28-2, complete sequence) position: , mismatch: 8, identity: 0.765

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
tcaagaaattcttaaaaataaatttgattataaa	Protospacer
* *. ******* ***.************ * * 

43. spacer 4.57|289729|35|NC_019678|PILER-CR matches to NZ_CP016890 (Pantoea agglomerans strain C410P1 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.771

cattgttgctaaatgtatttataaaatcaacagaa	CRISPR spacer
acttgttgctaaatgtattcatgaaattagcgaaa	Protospacer
  *****************.**.****.*.*..**

44. spacer 7.1|2244508|30|NC_019678|CRT matches to MH616673 (Microviridae sp. isolate ctce728, complete genome) position: , mismatch: 8, identity: 0.733

actcccgaacaaatgcgtcaacaccaacaa	CRISPR spacer
ctatgggaacaaatgcgtcaactccaacac	Protospacer
 . .  **************** ****** 

45. spacer 21.1|4614596|33|NC_019678|CRT matches to LC520287 (Escherichia coli HP129 plasmid pHP129 DNA, complete sequence) position: , mismatch: 8, identity: 0.758

ccttaaatggcggtaatggtgccgacttacttc	CRISPR spacer
tgcaaaatggaggtaatggtgccaacttactga	Protospacer
. . ****** ************.*******  

46. spacer 21.1|4614596|33|NC_019678|CRT matches to NZ_CP020508 (Serratia marcescens strain BWH-35 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

ccttaaatggcggtaatggtgccgacttacttc	CRISPR spacer
gctggattgtcggtaatggtgccaacttactga	Protospacer
 ** .* ** *************.*******  

47. spacer 21.1|4614596|33|NC_019678|CRT matches to NZ_CP020506 (Serratia marcescens strain 95 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

ccttaaatggcggtaatggtgccgacttacttc	CRISPR spacer
gctggattgtcggtaatggtgccaacttactga	Protospacer
 ** .* ** *************.*******  

48. spacer 21.4|4614758|33|NC_019678|CRT matches to NZ_CP024200 (Thalassospira marina strain CSC3H3 plasmid pCSC3H3, complete sequence) position: , mismatch: 8, identity: 0.758

gccttgaaggtggtaacggtaaagacgttctag	CRISPR spacer
cccttgaaggtggtaacggtaacgataccctga	Protospacer
 ********************* **....**..

49. spacer 21.4|4614758|33|NC_019678|CRT matches to NZ_KU896918 (Lactobacillus plantarum strain A-1 plasmid pA1_ASM1, complete sequence) position: , mismatch: 8, identity: 0.758

gccttgaaggtggtaacggtaaagac--gttctag	CRISPR spacer
tgctttaaggtagtaacggtaaagactagtccc--	Protospacer
  *** *****.**************  **.*.  

50. spacer 26.23|6182758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053834 (Arcobacter cloacae strain LMG 26153 plasmid pACLO, complete sequence) position: , mismatch: 8, identity: 0.758

tttacatcttgaattattttctttattcctaat-----	CRISPR spacer
tttaaatcttgaaatattttcttt-----taaagcatc	Protospacer
**** ******** **********     ***      

51. spacer 26.70|6186123|31|NC_019678|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.742

gttagtggttttttgcgaacctgcaaatccg	CRISPR spacer
gcgggctgttttttgcggacctgcaactcct	Protospacer
*. .*. **********.******** *** 

52. spacer 26.70|6186123|31|NC_019678|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.742

gttagtggttttttgcgaacctgcaaatccg	CRISPR spacer
gcgcgctgttttttgcggacctgcaactcct	Protospacer
*.  *. **********.******** *** 

53. spacer 26.70|6186123|31|NC_019678|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 8, identity: 0.742

gttagtggttttttgcgaacctgcaaatccg	CRISPR spacer
gcgggctgttttttgcggacctgcaactcct	Protospacer
*. .*. **********.******** *** 

54. spacer 26.70|6186123|31|NC_019678|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 8, identity: 0.742

gttagtggttttttgcgaacctgcaaatccg	CRISPR spacer
gcgcgctgttttttgcggacctgcaactcct	Protospacer
*.  *. **********.******** *** 

55. spacer 26.74|6186409|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR matches to HQ316603 (Cyanophage S-SSM6b genomic sequence) position: , mismatch: 8, identity: 0.758

-----gattgatcttcatagtcaaaattttcttctttc	CRISPR spacer
tctatgat-----ttcatagtcaaatttttcttcgttg	Protospacer
     ***     ************ ******** ** 

56. spacer 26.74|6186409|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR matches to NC_020875 (Cyanophage S-SSM4 genomic sequence) position: , mismatch: 8, identity: 0.758

-----gattgatcttcatagtcaaaattttcttctttc	CRISPR spacer
tctatgat-----ttcatagtcaaatttttcttcgttg	Protospacer
     ***     ************ ******** ** 

57. spacer 26.81|6186915|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015094 (Pelagibaca abyssi strain JLT2014 plasmid pPABY6, complete sequence) position: , mismatch: 8, identity: 0.771

gagacctccgaagatgctgtcattgccgtttccac	CRISPR spacer
ctggccgccgaagaggctgtcattgccgtcgccgc	Protospacer
  *.** ******* **************. **.*

58. spacer 26.85|6187204|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR matches to NC_001949 (Lactococcus lactis DPC3147 plasmid pMRC01, complete sequence) position: , mismatch: 8, identity: 0.758

tttaggaaacaaataaccccccaaaaaaaaaga	CRISPR spacer
attaaagaacaaataaccacccaaaaagaaatt	Protospacer
 ***...*********** ********.***  

59. spacer 33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MT074137 (Bacteroides phage DAC16, complete genome) position: , mismatch: 8, identity: 0.771

atcagtctttaattagatataatcatttaaaacaa	CRISPR spacer
aagaagctttaattagatataaacaattaaaaaag	Protospacer
*  *. **************** ** ****** *.

60. spacer 33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MT074142 (Bacteroides phage DAC23, complete genome) position: , mismatch: 8, identity: 0.771

atcagtctttaattagatataatcatttaaaacaa	CRISPR spacer
aagaagctttaattagatataaacaattaaaaaag	Protospacer
*  *. **************** ** ****** *.

61. spacer 33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MT074141 (Bacteroides phage DAC22, complete genome) position: , mismatch: 8, identity: 0.771

atcagtctttaattagatataatcatttaaaacaa	CRISPR spacer
aagaagctttaattagatataaacaattaaaaaag	Protospacer
*  *. **************** ** ****** *.

62. spacer 33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MT074139 (Bacteroides phage DAC19, complete genome) position: , mismatch: 8, identity: 0.771

atcagtctttaattagatataatcatttaaaacaa	CRISPR spacer
aagaagctttaattagatataaacaattaaaaaag	Protospacer
*  *. **************** ** ****** *.

63. spacer 33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MT074140 (Bacteroides phage DAC20, complete genome) position: , mismatch: 8, identity: 0.771

atcagtctttaattagatataatcatttaaaacaa	CRISPR spacer
aagaagctttaattagatataaacaattaaaaaag	Protospacer
*  *. **************** ** ****** *.

64. spacer 38.4|7450592|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NC_016821 (Leuconostoc mesenteroides subsp. mesenteroides J18 plasmid pKLE03, complete sequence) position: , mismatch: 8, identity: 0.758

ttataacctttgcttgtttgctcaagt--actaaa	CRISPR spacer
caataacctttgcttgttttatcaagtcgattt--	Protospacer
. *****************  ******  *.*   

65. spacer 38.4|7450592|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014603 (Leuconostoc mesenteroides subsp. mesenteroides strain DRC0211 plasmid pDSK3, complete sequence) position: , mismatch: 8, identity: 0.758

ttataacctttgcttgtttgctcaagt--actaaa	CRISPR spacer
caataacctttgcttgttttatcaagtcgattt--	Protospacer
. *****************  ******  *.*   

66. spacer 38.4|7450592|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014603 (Leuconostoc mesenteroides subsp. mesenteroides strain DRC0211 plasmid pDSK3, complete sequence) position: , mismatch: 8, identity: 0.758

ttataacctttgcttgtttgctcaagt--actaaa	CRISPR spacer
caataacctttgcttgttttatcaagtcgattt--	Protospacer
. *****************  ******  *.*   

67. spacer 38.4|7450592|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MK415406 (Phage FAKO27_000238F, complete genome) position: , mismatch: 8, identity: 0.758

ttataacctttgcttgtttgctcaagtactaaa	CRISPR spacer
cgataaccttttcttgtttgctcacgtgcgtag	Protospacer
. ********* ************ **.*  *.

68. spacer 38.4|7450592|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to KT070867 (Bacillus phage PBC2, complete genome) position: , mismatch: 8, identity: 0.758

ttataacctttgcttgtttgctcaagtactaaa	CRISPR spacer
atatctgtattgcctgtttgctcaaatactaaa	Protospacer
 ***   . ****.***********.*******

69. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NC_015598 (Lactobacillus kefiranofaciens ZW3 plasmid pWW1, complete sequence) position: , mismatch: 9, identity: 0.735

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
gaaggtgaaaaaatatatgattaaaaataagaaa	Protospacer
  *.  . ************.**** ********

70. spacer 4.2|287070|32|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to KY065492 (Streptococcus phage IPP54, complete genome) position: , mismatch: 9, identity: 0.719

ttgctacctgcatctttattatcgggctttat	CRISPR spacer
ttgctatcagcatctttattatcatcaatcaa	Protospacer
******.* **************.    *.* 

71. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MK496764 (Capybara microvirus Cap3_SP_319, complete genome) position: , mismatch: 9, identity: 0.735

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aaaataaaaatatggaaaagaaaaaaagaggagg	Protospacer
**************.******* **.*.*..  .

72. spacer 4.18|288220|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038016 (Paenisporosarcina antarctica strain CGMCC 1.6503 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

caagcttt----ttaccgtttgtaacaccactagaacc	CRISPR spacer
----ccttgccattaccgtttgtatcaacactagaaat	Protospacer
    *.**    ************ ** ******** .

73. spacer 4.31|289154|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MN830254 (Lactobacillus phage JNU_P2, complete genome) position: , mismatch: 9, identity: 0.735

tgattcaactcttgagaaaacatttgtctatcta	CRISPR spacer
agtatcaacgcttgagacaacatttgtcccactg	Protospacer
 *  ***** ******* **********.  **.

74. spacer 4.31|289154|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MN830255 (Lactobacillus phage JNU_P4, complete genome) position: , mismatch: 9, identity: 0.735

tgattcaactcttgagaaaacatttgtctatcta	CRISPR spacer
agtatcaacgcttgagacaacatttgtcccactg	Protospacer
 *  ***** ******* **********.  **.

75. spacer 4.39|289730|34|NC_019678|CRISPRCasFinder,CRT matches to NZ_CP027853 (Plesiomonas shigelloides strain MS-17-188 plasmid pPS-MS-17-188-1, complete sequence) position: , mismatch: 9, identity: 0.735

attgttgctaaatgtatttataaaatcaacagaa	CRISPR spacer
ttcagtgctaaatgtttttataaaataaacgcag	Protospacer
 *.. ********** ********** ***. *.

76. spacer 4.39|289730|34|NC_019678|CRISPRCasFinder,CRT matches to KU594606 (Cyanophage S-RIM32 isolate RW_108_0702, complete genome) position: , mismatch: 9, identity: 0.735

attgttgctaaatgtatttataaaatcaacagaa	CRISPR spacer
acagttgctaaatgtattgatcaaatctatgaag	Protospacer
*. *************** ** ***** *...*.

77. spacer 4.43|290017|35|NC_019678|CRISPRCasFinder,CRT matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 9, identity: 0.743

taaaagattaatattacaatcttcaaaaattgata	CRISPR spacer
aataaatttaatagtacgatcttcaaaaattggat	Protospacer
 * **. ****** ***.**************.  

78. spacer 4.45|290160|34|NC_019678|CRISPRCasFinder,CRT matches to NZ_CP039965 (Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.735

cttatgctcctgaaggcgtgttgtttgtggatga	CRISPR spacer
ggcaggccggtgacggcgtgttgtttctggatga	Protospacer
  .* **.  *** ************ *******

79. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to MN241318 (Enterococcus phage PEf771, complete genome) position: , mismatch: 9, identity: 0.735

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
agacggaagtctaaaagataaatttgatttagag	Protospacer
 .*  .** *********************  * 

80. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to MN027503 (Enterococcus phage vB_OCPT_Ben, complete genome) position: , mismatch: 9, identity: 0.735

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
agacggaagtctaaaagataaatttgatttagag	Protospacer
 .*  .** *********************  * 

81. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to CAJDKA010000002 (Enterococcus phage 163 genome assembly, contig: phage163-genome, whole genome shotgun sequence) position: , mismatch: 9, identity: 0.735

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
agacggaagtctaaaagataaatttgatttagag	Protospacer
 .*  .** *********************  * 

82. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to MT856905 (Enterococcus phage vB_EfaM_A2, complete genome) position: , mismatch: 9, identity: 0.735

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
agacggaagtctaaaagataaatttgatttagag	Protospacer
 .*  .** *********************  * 

83. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to MW004544 (Enterococcus phage EFGrKN, complete genome) position: , mismatch: 9, identity: 0.735

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
agacggaagtctaaaagataaatttgatttagag	Protospacer
 .*  .** *********************  * 

84. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to NC_029009 (Enterococcus phage EFDG1, complete genome) position: , mismatch: 9, identity: 0.735

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
agacggaagtctaaaagataaatttgatttagag	Protospacer
 .*  .** *********************  * 

85. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to MH880817 (Enterococcus phage EfV12-phi1, complete genome) position: , mismatch: 9, identity: 0.735

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
agacggaagtctaaaagataaatttgatttagag	Protospacer
 .*  .** *********************  * 

86. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to MN693785 (Marine virus AFVG_250M536, complete genome) position: , mismatch: 9, identity: 0.735

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
aaatttaattttaaaagataagtttgattttgga	Protospacer
 ** . ****.**********.********* . 

87. spacer 4.54|290810|34|NC_019678|CRISPRCasFinder,CRT matches to MT932329 (Campylobacter phage F379, complete genome) position: , mismatch: 9, identity: 0.735

tatcaaaaatatttcatttgaagaacctttcaaa	CRISPR spacer
cctttgaagtatttcatttaaagaacctttaata	Protospacer
. *. .**.**********.********** * *

88. spacer 4.54|290810|34|NC_019678|CRISPRCasFinder,CRT matches to MK408758 (Campylobacter phage CP20, complete genome) position: , mismatch: 9, identity: 0.735

tatcaaaaatatttcatttgaagaacctttcaaa	CRISPR spacer
cttttgaagtatttcatttaaagaacctttaata	Protospacer
. *. .**.**********.********** * *

89. spacer 4.54|290810|34|NC_019678|CRISPRCasFinder,CRT matches to HM246721 (Campylobacter phage vB_CcoM-IBB_35 clone Contig2, complete sequence) position: , mismatch: 9, identity: 0.735

tatcaaaaatatttcatttgaagaacctttcaaa	CRISPR spacer
cttttgaagtatttcatttaaagaacctttaata	Protospacer
. *. .**.**********.********** * *

90. spacer 4.54|290810|34|NC_019678|CRISPRCasFinder,CRT matches to FN667788 (Campylobacter phage CP220, complete genome) position: , mismatch: 9, identity: 0.735

tatcaaaaatatttcatttgaagaacctttcaaa	CRISPR spacer
cctttgaagtatttcatttaaagaacctttaata	Protospacer
. *. .**.**********.********** * *

91. spacer 4.54|290810|34|NC_019678|CRISPRCasFinder,CRT matches to FN667789 (Campylobacter phage CPt10, complete genome) position: , mismatch: 9, identity: 0.735

tatcaaaaatatttcatttgaagaacctttcaaa	CRISPR spacer
cttttgaagtatttcatttaaagaacctttaata	Protospacer
. *. .**.**********.********** * *

92. spacer 7.3|2244592|30|NC_019678|CRT matches to KP671755 (Vibrio phage ValKK3, complete genome) position: , mismatch: 9, identity: 0.7

actccggaacaaatacgtcagcatcaccaa	CRISPR spacer
cgattgacacatatacgtcagcatcaccat	Protospacer
   ..*. *** ***************** 

93. spacer 7.3|2244592|30|NC_019678|CRT matches to MF042360 (Pseudomonas phage Phabio, complete genome) position: , mismatch: 9, identity: 0.7

actccggaacaaatacgtcagcatcaccaa	CRISPR spacer
tgcttgtaacaaacacgtcagcatcaccgg	Protospacer
  ...* ******.**************..

94. spacer 7.3|2244592|30|NC_019678|CRT matches to KT919972 (Vibrio phage phi-Grn1, complete genome) position: , mismatch: 9, identity: 0.7

actccggaacaaatacgtcagcatcaccaa	CRISPR spacer
cgattgacacatatacgtcagcatcaccat	Protospacer
   ..*. *** ***************** 

95. spacer 21.1|4614596|33|NC_019678|CRT matches to NC_011282 (Klebsiella variicola strain 342 plasmid pKP187, complete sequence) position: , mismatch: 9, identity: 0.727

ccttaaatggcggtaatggtgccgacttacttc	CRISPR spacer
acttaaatggcggtgatggtgctgaccaataaa	Protospacer
 *************.*******.***. *.   

96. spacer 21.1|4614596|33|NC_019678|CRT matches to NZ_CP044049 (Klebsiella variicola strain FDAARGOS_627 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

ccttaaatggcggtaatggtgccgacttacttc	CRISPR spacer
acttaaatggcggtgatggtgctgaccaataaa	Protospacer
 *************.*******.***. *.   

97. spacer 21.2|4614650|33|NC_019678|CRT matches to NZ_CP024200 (Thalassospira marina strain CSC3H3 plasmid pCSC3H3, complete sequence) position: , mismatch: 9, identity: 0.727

gccttgaaggtggtaacggtagagatgttttag	CRISPR spacer
cccttgaaggtggtaacggtaacgataccctga	Protospacer
 ********************. ***....*..

98. spacer 21.3|4614704|33|NC_019678|CRT matches to NC_011282 (Klebsiella variicola strain 342 plasmid pKP187, complete sequence) position: , mismatch: 9, identity: 0.727

ccttaaatggcggcaatggtgctgacttacttc	CRISPR spacer
acttaaatggcggtgatggtgctgaccaataaa	Protospacer
 ************..***********. *.   

99. spacer 21.3|4614704|33|NC_019678|CRT matches to NZ_CP044049 (Klebsiella variicola strain FDAARGOS_627 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

ccttaaatggcggcaatggtgctgacttacttc	CRISPR spacer
acttaaatggcggtgatggtgctgaccaataaa	Protospacer
 ************..***********. *.   

100. spacer 21.5|4614812|33|NC_019678|CRT matches to NC_011282 (Klebsiella variicola strain 342 plasmid pKP187, complete sequence) position: , mismatch: 9, identity: 0.727

ccttaaatggcggcaatggtgctgacttacttc	CRISPR spacer
acttaaatggcggtgatggtgctgaccaataaa	Protospacer
 ************..***********. *.   

101. spacer 21.5|4614812|33|NC_019678|CRT matches to NZ_CP044049 (Klebsiella variicola strain FDAARGOS_627 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

ccttaaatggcggcaatggtgctgacttacttc	CRISPR spacer
acttaaatggcggtgatggtgctgaccaataaa	Protospacer
 ************..***********. *.   

102. spacer 26.17|6182328|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to GU233956 (Bacillus phage 11143, partial sequence) position: , mismatch: 9, identity: 0.743

attaattgc--ttttaatttcacttgttgtttccttt	CRISPR spacer
--cagcttctgttttaatttcagttgttgttttcttg	Protospacer
  .*..* *  *********** *********.*** 

103. spacer 26.23|6182758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049807 (Acinetobacter pittii strain A1254 plasmid pA1254_1, complete sequence) position: , mismatch: 9, identity: 0.727

tttacatcttgaattattttctttattcctaat	CRISPR spacer
tttacatattgaattattttatttctcggagct	Protospacer
******* ************ *** *.   . *

104. spacer 26.51|6184758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MT074137 (Bacteroides phage DAC16, complete genome) position: , mismatch: 9, identity: 0.727

tttaaaaattaaaatattacttaaaataatttt	CRISPR spacer
attaaaaaataaaatattacctaaagaattaac	Protospacer
 ******* ***********.****. * *  .

105. spacer 26.51|6184758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MT074142 (Bacteroides phage DAC23, complete genome) position: , mismatch: 9, identity: 0.727

tttaaaaattaaaatattacttaaaataatttt	CRISPR spacer
attaaaaaataaaatattacctaaagaattaac	Protospacer
 ******* ***********.****. * *  .

106. spacer 26.51|6184758|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MT074146 (Bacteroides phage SJC03, complete genome) position: , mismatch: 9, identity: 0.727

tttaaaaattaaaatattacttaaaataatttt	CRISPR spacer
attaaaaaataaaatattacctaaagaattaac	Protospacer
 ******* ***********.****. * *  .

107. spacer 26.74|6186409|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR matches to MF001361 (Enterococcus phage EF5, partial genome) position: , mismatch: 9, identity: 0.727

gattgatcttcatagtcaaaattttcttctttc	CRISPR spacer
caactttcttcatcttcaaaattttcttcttca	Protospacer
 * .  *******  ****************. 

108. spacer 26.74|6186409|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR matches to MF001358 (Enterococcus phage EF1, partial genome) position: , mismatch: 9, identity: 0.727

gattgatcttcatagtcaaaattttcttctttc	CRISPR spacer
caactttcttcatcttcaaaattttcttcttca	Protospacer
 * .  *******  ****************. 

109. spacer 26.74|6186409|33|NC_019678|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013927 (Alteromonas stellipolaris strain LMG 21861 plasmid pASTE61-200, complete sequence) position: , mismatch: 9, identity: 0.727

gattgatcttcatagtcaaaattttcttctttc	CRISPR spacer
gtgctcttttcaaagtaaaaattttcttctttg	Protospacer
*  .  *.**** *** *************** 

110. spacer 33.13|6752258|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NC_007110 (Rickettsia felis URRWXCal2 plasmid pRF, complete sequence) position: , mismatch: 9, identity: 0.735

aatta--catcctgtatttgctctttctttgaatta	CRISPR spacer
--ttggtaaacctgtttttgctctttctttgtatgg	Protospacer
  **.   * ***** *************** ** .

111. spacer 33.13|6752258|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NC_007111 (Rickettsia felis URRWXCal2 plasmid pRFdelta, complete sequence) position: , mismatch: 9, identity: 0.735

aatta--catcctgtatttgctctttctttgaatta	CRISPR spacer
--ttggtaaacctgtttttgctctttctttgtatgg	Protospacer
  **.   * ***** *************** ** .

112. spacer 33.13|6752258|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NC_019229 (Rickettsia felis plasmid pRF, complete sequence) position: , mismatch: 9, identity: 0.735

aatta--catcctgtatttgctctttctttgaatta	CRISPR spacer
--ttggtaaacctgtttttgctctttctttgtatgg	Protospacer
  **.   * ***** *************** ** .

113. spacer 33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to AP013489 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C30A-MedDCM-OCT-S45-C81) position: , mismatch: 9, identity: 0.743

atcagtctttaattagatataatcatttaaaacaa	CRISPR spacer
acacttatgaaattagatataattatttacaacaa	Protospacer
*.   * *  *************.***** *****

114. spacer 33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MN698245 (Pelagibacter phage HTVC111P, complete genome) position: , mismatch: 9, identity: 0.743

atcagtctttaattagatataatcatttaaaacaa	CRISPR spacer
acacttatgaaattagatataattatttacaacaa	Protospacer
*.   * *  *************.***** *****

115. spacer 33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to AP013487 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C30A-MedDCM-OCT-S33-C83) position: , mismatch: 9, identity: 0.743

atcagtctttaattagatataatcatttaaaacaa	CRISPR spacer
acacttatgaaattagatataattatttacaacaa	Protospacer
*.   * *  *************.***** *****

116. spacer 33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to AP013488 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C30A-MedDCM-OCT-S38-C82) position: , mismatch: 9, identity: 0.743

atcagtctttaattagatataatcatttaaaacaa	CRISPR spacer
acacttatgaaattagatataattatttacaacaa	Protospacer
*.   * *  *************.***** *****

117. spacer 33.14|6752329|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to AP013486 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C30A-MedDCM-OCT-S29-C73) position: , mismatch: 9, identity: 0.743

atcagtctttaattagatataatcatttaaaacaa	CRISPR spacer
acacttatgaaattagatataattatttacaacaa	Protospacer
*.   * *  *************.***** *****

118. spacer 33.15|6752401|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040718 (Aeromonas veronii strain HX3 plasmid pHX3, complete sequence) position: , mismatch: 9, identity: 0.727

atattcttgctgcaatttcaggatgcactgtat	CRISPR spacer
gaaaagttcctgcaatttcaggatgaactggag	Protospacer
. *   ** **************** **** * 

119. spacer 38.4|7450592|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MK448893 (Streptococcus phage Javan270, complete genome) position: , mismatch: 9, identity: 0.727

ttataacctttgcttgtttgctcaagtactaaa	CRISPR spacer
tctaaacccttgcttgtctgctcaagtagagca	Protospacer
*.  ****.********.**********  . *

120. spacer 4.7|287431|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040940 (Cetia pacifica strain TB6 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.714

aaaaaaagactataaatcctcaaataagttgagtt	CRISPR spacer
ttaaaaatactaaaaatcctcaaataattagtaaa	Protospacer
  ***** **** ************** * * .  

121. spacer 4.7|287431|35|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to CP016195 (Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-1, complete sequence) position: , mismatch: 10, identity: 0.714

aaaaaaagactataaatcctcaaataagttgagtt	CRISPR spacer
aaaaaaatactaaaaatcctcaaattgaaaggcat	Protospacer
******* **** ************ ..  *.  *

122. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KU525621 (Bacillus anthracis strain P.NO2 plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

123. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NC_014332 (Bacillus cereus biovar anthracis str. CI plasmid pCI-XO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

124. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NC_012577 (Bacillus anthracis str. CDC 684 plasmid pX02, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

125. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015778 (Bacillus anthracis strain Tangail-1 plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

126. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018905 (Bacillus anthracis strain Tyrol 4675 plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

127. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023003 (Bacillus anthracis strain 14RA5914 plasmid pX02, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

128. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019733 (Bacillus anthracis strain PCr plasmid PCr-pXO2) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

129. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP018445 (Bacillus anthracis strain CZC5 plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

130. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029325 (Bacillus anthracis strain 17OD930 plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

131. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NC_012655 (Bacillus anthracis str. A0248 plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

132. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NC_007323 (Bacillus anthracis str. 'Ames Ancestor' plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

133. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024976 (Escherichia coli strain CV839-15 plasmid pCV839-15-p2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aaaataaaaatatgaaaaaaagcatcatcgttgg	Protospacer
*******************.*.**  *  . * .

134. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010854 (Bacillus anthracis strain A1144 plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

135. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007617 (Bacillus anthracis strain 2000031021 plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

136. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP008848 (Bacillus anthracis strain HYU01 plasmid pX02, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

137. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP006744 (Bacillus anthracis str. SVA11 plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

138. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014835 (Bacillus anthracis strain Shikan-NIID plasmid pXO2) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

139. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029807 (Bacillus anthracis strain London_499 plasmid pX02, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

140. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NC_002146 (Bacillus anthracis plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

141. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NC_017727 (Bacillus anthracis str. H9401 plasmid BAP2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

142. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009314 (Bacillus anthracis str. Turkey32 strain 35 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

143. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014178 (Bacillus anthracis strain Stendal plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

144. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009475 (Bacillus anthracis strain Pasteur plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

145. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009900 (Bacillus anthracis strain 2002013094 plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

146. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009339 (Bacillus anthracis strain Ohio ACB plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

147. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009695 (Bacillus anthracis strain RA3 plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

148. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009462 (Bacillus anthracis strain SK-102 plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

149. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009698 (Bacillus anthracis strain BA1035 plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

150. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009542 (Bacillus anthracis strain BA1015 plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

151. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010320 (Bacillus anthracis strain Canadian Bison isolate A0369 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

152. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009329 (Bacillus anthracis strain K3 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

153. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009326 (Bacillus anthracis strain Vollum 1B plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

154. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009979 (Bacillus anthracis strain Ames isolate BACI008 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

155. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP001972 (Bacillus anthracis str. A16 plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

156. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP047133 (Bacillus anthracis str. BF1 plasmid pXO2, complete sequence) position: , mismatch: 10, identity: 0.706

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
aggtaaaatatatgagaaagaacaagaaattaaa	Protospacer
*..  *** ******.*************    *

157. spacer 4.18|288220|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP008877 (Terribacillus goriensis strain MP602 plasmid pT1, complete sequence) position: , mismatch: 10, identity: 0.706

caagctttttaccgtttgtaacaccactagaacc	CRISPR spacer
cctgtccattaccgtttgtatcaacactagaaat	Protospacer
*  *... ************ ** ******** .

158. spacer 4.21|288435|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NC_024792 (Bacillus phage Bobb, complete genome) position: , mismatch: 10, identity: 0.706

aaagaatttagcactacggctgcacctgctgaat	CRISPR spacer
agcacaaaaagtactactgctgcacctgctgaag	Protospacer
*. . *   **.***** *************** 

159. spacer 4.33|289296|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 10, identity: 0.706

ccccgaaaaaaccaagcccagcaactctgattga	CRISPR spacer
ccccgacaaaaccaaggccagcaaagccaaggcc	Protospacer
****** ********* *******  *..*    

160. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to MN693021 (Marine virus AFVG_117M32, complete genome) position: , mismatch: 10, identity: 0.706

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
ttcataaattataaaagaaaaatttgatttaggg	Protospacer
*  ..***** ******* ***********  . 

161. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to NZ_LR214994 (Mycoplasma hyopneumoniae strain NCTC10127 plasmid 3) position: , mismatch: 10, identity: 0.706

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
atatcaatttctaaaaaataaatttgataggctt	Protospacer
  * *** ********.***********   . *

162. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to NZ_LR214995 (Mycoplasma hyopneumoniae strain NCTC10127 plasmid 4) position: , mismatch: 10, identity: 0.706

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
atatcaatttctaaaaaataaatttgataggctt	Protospacer
  * *** ********.***********   . *

163. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to MN694380 (Marine virus AFVG_250M409, complete genome) position: , mismatch: 10, identity: 0.706

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
tgttaaaattttaaaagataaatatgattcatca	Protospacer
*.   *****.************ *****. *  

164. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to KY549443 (Enterococcus phage EFP01, complete genome) position: , mismatch: 10, identity: 0.706

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
agacggaagtctaaaagataagtttgatttagag	Protospacer
 .*  .** ************.********  * 

165. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to MN693770 (Marine virus AFVG_250M115, complete genome) position: , mismatch: 10, identity: 0.706

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
tgttaaaattcttaaagataaatatgattcatca	Protospacer
*.   ******* ********** *****. *  

166. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to MT909815 (Enterococcus phage iF6, complete genome) position: , mismatch: 10, identity: 0.706

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
agacggaagtctaaaagataagtttgatttagag	Protospacer
 .*  .** ************.********  * 

167. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to MN694329 (Marine virus AFVG_250M203, complete genome) position: , mismatch: 10, identity: 0.706

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
tgttaaaattttaaaagataaatatgattcatca	Protospacer
*.   *****.************ *****. *  

168. spacer 4.57|289729|35|NC_019678|PILER-CR matches to NZ_CP027853 (Plesiomonas shigelloides strain MS-17-188 plasmid pPS-MS-17-188-1, complete sequence) position: , mismatch: 10, identity: 0.714

cattgttgctaaatgtatttataaaatcaacagaa	CRISPR spacer
attcagtgctaaatgtttttataaaataaacgcag	Protospacer
  *.. ********** ********** ***. *.

169. spacer 4.68|290516|35|NC_019678|PILER-CR matches to MN693785 (Marine virus AFVG_250M536, complete genome) position: , mismatch: 10, identity: 0.714

ctaagcaaattctaaaagataaatttgatttttat	CRISPR spacer
gaaatttaattttaaaagataagtttgattttgga	Protospacer
  ** . ****.**********.********* . 

170. spacer 26.36|6183680|37|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NC_013160 (Rippkaea orientalis PCC 8802 plasmid pP880201, complete sequence) position: , mismatch: 10, identity: 0.73

gttagtaaattactttacaagaaaaatcttgtaattg	CRISPR spacer
ctctttacattactttacaataaaaatcttggtagtc	Protospacer
 *.  ** ************ **********  * * 

171. spacer 26.41|6184047|32|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MN855600 (Bacteriophage sp. isolate 296, complete genome) position: , mismatch: 10, identity: 0.688

caccattatttgtttgagtggtagggggatga	CRISPR spacer
gaccattattcgtttgactggtagtaccccta	Protospacer
 *********.****** ****** .   . *

172. spacer 26.44|6184257|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to CP031730 (Stenotrophomonas rhizophila strain GA1 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

actaacccacacaatgaggctgaatgaatttttt	CRISPR spacer
attaagccatacaatgaggctgaatgggcaatgc	Protospacer
*.*** ***.****************...  * .

173. spacer 26.81|6186915|35|NC_019678|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP051182 (Thalassobius gelatinovorus strain NEB572 plasmid pAge77, complete sequence) position: , mismatch: 10, identity: 0.714

gagacctccgaagatgctgtcattgccgtttccac	CRISPR spacer
ggcaccgccgaacatgctgtcattgccgccatcgg	Protospacer
*. *** ***** ***************.. .*. 

174. spacer 33.15|6752401|33|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MN693532 (Marine virus AFVG_25M340, complete genome) position: , mismatch: 10, identity: 0.697

atattcttgctgcaatttcaggatgcactgtat	CRISPR spacer
atactcttgctggaatttcaggattatcaactc	Protospacer
***.******** ***********   * .. .

175. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KX839207 (Klebsiella pneumoniae strain KP1814 plasmid pKP1814-1, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

176. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021328 (Raoultella ornithinolytica strain Ro24724 plasmid pRo24724, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

177. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019048 (Klebsiella pneumoniae subsp. pneumoniae strain RJA166 plasmid pRJA166a, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

178. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022441 (Klebsiella sp. LY plasmid unnamed3, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

179. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024641 (Klebsiella michiganensis strain F107 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

180. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026369 (Klebsiella quasipneumoniae strain A708 plasmid pA708-1, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

181. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028952 (Klebsiella aerogenes strain AR_0161 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

182. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to MN661402 (Klebsiella quasipneumoniae strain KP18-31 plasmid pKP18-31-IMP,KPC, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

183. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY270853 (Raoultella ornithinolytica strain YNKP001 plasmid pYNKP001-dfrA, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

184. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025467 (Klebsiella pneumoniae strain JS187 plasmid p187-1, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

185. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NC_018107 (Klebsiella michiganensis E718 plasmid pKOX_R1, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

186. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to KU318421 (Klebsiella pneumoniae strain KP04 plasmid pKP04VIM, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

187. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NC_023911 (Raoultella planticola strain KpNDM1 plasmid pKpNDM1, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

188. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025964 (Klebsiella pneumoniae strain WCHKP34 plasmid pIMP4_LL34, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

189. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038277 (Raoultella ornithinolytica strain WLK218 plasmid pWLK-238550, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

190. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to CP027603 (UNVERIFIED_ORG: Klebsiella pneumoniae strain AR_0080 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

191. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046614 (Klebsiella pneumoniae strain WCGKP294 plasmid pWCGKP294-2, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

192. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026014 (Klebsiella variicola strain 13450 plasmid p13450-1, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

193. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026019 (Klebsiella pneumoniae strain 13190 plasmid p13190-1, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

194. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MF344561 (Klebsiella pneumoniae strain 11219 plasmid p11219-IMP, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

195. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MF344566 (Klebsiella pneumoniae strain A324 plasmid pA324-IMP, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

196. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MF344565 (Klebsiella pneumoniae strain 19051 plasmid p19051-IMP, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

197. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MF344562 (Klebsiella pneumoniae strain 12208 plasmid p12208-IMP, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

198. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MF344567 (Klebsiella pneumoniae strain A708 plasmid pA708-IMP, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

199. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MF344563 (Klebsiella pneumoniae strain 13190 plasmid p13190-VIM, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

200. spacer 1.2|62999|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MF344564 (Klebsiella pneumoniae strain 13450 plasmid p13450-IMP, complete sequence) position: , mismatch: 11, identity: 0.676

ccaatgacaaaaatatatgactaaatataagaaa	CRISPR spacer
tatatgaaaaaaatatatgacaaaatacctgctt	Protospacer
.  **** ************* *****.  *   

201. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to NZ_CP038259 (Acinetobacter baumannii strain 39741 plasmid pEH_gr13, complete sequence) position: , mismatch: 11, identity: 0.676

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
cacttcaattttaaaagatgaatttgatttaagc	Protospacer
.*  . ****.********.**********  ..

202. spacer 4.68|290516|35|NC_019678|PILER-CR matches to MN693021 (Marine virus AFVG_117M32, complete genome) position: , mismatch: 11, identity: 0.686

ctaagcaaattctaaaagataaatttgatttttat	CRISPR spacer
tttcataaattataaaagaaaaatttgatttaggg	Protospacer
.*  ..***** ******* ***********  . 

203. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214999 (Mycoplasma conjunctivae strain NCTC10147 plasmid 3) position: , mismatch: 12, identity: 0.647

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
tgtcataaaatatgaaaaagaacatcaaaatggt	Protospacer
 .    ******************  ****    

204. spacer 4.15|288005|34|NC_019678|PILER-CR,CRISPRCasFinder,CRT matches to LR214965 (Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 11) position: , mismatch: 12, identity: 0.647

aaaataaaaatatgaaaaagaacaagaaaaatca	CRISPR spacer
tgtcataaaatatgaaaaagaacatcaaaatggt	Protospacer
 .    ******************  ****    

205. spacer 4.50|290517|34|NC_019678|CRISPRCasFinder,CRT matches to NZ_CP023367 (Escherichia coli strain 1428 plasmid p111, complete sequence) position: , mismatch: 12, identity: 0.647

taagcaaattctaaaagataaatttgatttttat	CRISPR spacer
agtatcaattcttaaagataaatttgctttacca	Protospacer
 . .. ****** ************* *** .  

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1727397 : 1759812	25	Indivirus(33.33%)	protease,transposase	NA
DBSCAN-SWA_2	2134732 : 2149324	13	Bacillus_phage(66.67%)	plate,tail	NA
DBSCAN-SWA_3	5028608 : 5109614	60	Bacteriophage(33.33%)	protease,transposase	NA
DBSCAN-SWA_4	6504720 : 6556934	28	Streptomyces_phage(25.0%)	plate,tail,transposase	NA
DBSCAN-SWA_5	7907518 : 7956560	30	Bacteriophage(28.57%)	bacteriocin,integrase,transposase	attL 7939002:7939017|attR 7958771:7958786

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_019678|1727397:1759812|DBSCAN-SWA
CTCACTGCTCACTGCTCGCTGTTAACTGCTTTTGACGCATCCACAAAGCTAATAAAGTCAAACTCAATAAGCCCATTACCCCAGCCAAGGGATTATTGTTTACACCAGTAACCCACTGGGGAACGGTTCCAGAATACTTGATTAATTTTCCTACCTCAATTATGTAGTTACCCCAAACTAAACCCCCATGGAGTCCAATCGGTAAGCCCAAGCGTCCCCTGCAACTGCGTTTAGCCCAAACACAGGCTAAGCCTAATAATAATAATCCGAGAAATTGCGGCGATGTACTTATGATTACCGGCAATGGTTTGATAAAGTGCAACACGGCAAAAATAATTGCAGTCGCTGGTATTACCACCGCAGGATTATAATCTCGCTGTAATTCATCATATATAAACCCCCGGAAAAACAATTCTTCCGCAAAAGCCACACCCAAACCTGTTAACAACCCTTCCAAAACTAATTGCAGCATCGAAAAACCAGGCGGCTGCCAGACTAACCAACCTAGCATTCCCTGTACAACGAATAATGCTAAAACACTAATCAGCCCAATTGCGACACCACGCAGCAACTCCACACCATTTTTCCGCGTAAACTCCAAACCATAGTGACGAAATGCTTGGGGCTGCTGATGGATATATTTACTCCACCAAGGAAGTAAAAATAGAAACTCAATTGCCAAAATACCCATAGTTAAGATAGTTCGGGTATTTTCGTCTTTGACTAAAATATAAACTGCTGCCGCATAAGGCAACCACGGCAATAATAAACTCAAAATAAAGCAGCCCAACCTTATAGGGGCAGGGCGCACAGATAAACTAAATAAATTAATTTTCATACCAAGTTGTTTGTACAGGTAAAGATTGGGTAGCACCAAAAGATTTATATTATCTGATGTTGCTCTACCACGCTTGTCAAACCGACGGCAACTTGGTATGTGCAGTTTCTTTTTTATACAATCTCAGTCTTCCGGTTCTATAGTGCTGTTTAACCCGTGAGTTTTGAGGGTTTCGCTATAAAATTCGGCATGTTCCTGAGCGCAAGTAATAACTAAAGCAAAGCCATTTGTATGGGCTTCCATCATGATGCTTACAGCCTGGGGTTGGCTGAGGCTCGGCACTGTGGTGATTAGTATCTCCACCACATACTCCATAGCGTTGTAGTCATCATTATGGAGCAAAACACGGTACCGAGGCGCGTGCTTCCGGGTTGTTGAACGCTTCTCTATAGTTTCGACTGACACGATTAGTATGCTTCTTCTCGTTTGTTTACTACAACAGACTGGTTTCTATACTTTACTTAACACTTATTCATAGTATTGTATCGCATCTAATTATCATGCCCAAATATATGATAAGTTTTCTGCGGTCGATTGCGGTCGATTAATTATTGCATTGTGAATTCAGGATTGCGAGAGTACTGGCTTACATGACTCGGTTTAGTTGCATTTCCACAAGTAAAATAGATGAAAATAGATAGATAAAGTAAGCTCGTAATCCTTTTCGCCCCATTAATTCGTAAATATGGAGATAAAAGCAAATTTTCAAGCCGGACAAATAGTCTTCCTGGAATACAAAGATAGCAGGCTATATACGGAAGTTATTCAGGTAGTAGTTGAACGTGATTTGTACTGGGTACGTCCGTTACTGCTTGTCGATCAACAATACTCGGAAGCACAACAGGTAACTGATTTGCGCTCTACTTCCGACTTGCTCTGGCCGATAAATTTGTTTCAACCAGCTTTGGATACTCAAGTAGTTGAACTGTACGCTCAGATTTTAATCAAAGAACCAAAACCAGAATTATCTCAAACCGCTAAACAAAAGCTACATCAGTTTATTCAGGAACTTTGGCAAGCGAATCAAAACGAAGCGTGATAATACTATAGATTCTAGGTTTTTGAAAGAATATGCTTGATATAAAATAAAATTTGATGGGTTCTGTAAAGAATAATGCGTTACGACTAGAAATATATTTATCGTCAACTTTAAACTTAAAACTATAACGTCGTAACGCAATCTAATTCCTAAAAATTTGCTGTTTTAGGCAATCTGAGAATAACTTGGATTCCTTTGAGGTACTTGAGGTGTACGATAGGGGTGGTTAATTTCAAATTCACTGGGATCGGAACAGCCAGTTTCTGACATAAAAGTTTGTACTAATTCACGATATACAAACCATTGCTTGTGAAGATGACGAATTAATTCTGGTTCCATTTTAAAGACATCCGAGTTTTGAAATCCGGCTCTAGATAACCATTCGTAAATAGAAAGAGTCTCGCCATTATTGTTGTGAAGCATTTTTCCTCCTGATAATCTTGGAATTGAGGTTAAAATACGCTTCAAAGATGCTACCCGAAGCGTTTACTAGTTATTTCAAGCGATGGCTATAAATGGGAACTAATAAATAAAACGATTTATCCCGCTACTTTTCTATATAAGAAAAGCAATATGGAAGCCCTTTTCACCCATATTTGAGCAAGAGTCAAAATCAAAAAGTATTTCTAGCCAACAGTCTTGCTGGCTCAATACAAGTATCAATATCTATCCGAGTCTAACTTGGAGAGTGTAAAAAGAAAATCCGAAATATCACCCTATTAAGCAGTTGATACTTTTACCATAAATATTCAGCCAGATAAATCTTTAGTACTGCTCTAAAAAAGTTATACCTGCCTTCACAAGTATCCACTCTAAGCAAGTATTTAATATTATTTTCCTGAAAATAGCAAAATCAATCTATCCTTCTAAAGTTATATATTTACTGTTTGACCCATATGATGAATTGAAACTTAATATTTTTGCGAACCGTTTTCCAGAATTCTAATAATACATCATTGAAAAGCACTTTTTTCATAAAACTTAGGGGATTCCCCTAGGTTCAATAGTTACCCCTAGCGATGAAACCCTTTAAATAAAGGGGTTTTCCGAATATTTTTAATCTTATTAGCTTGAGGGAATTGTCTGCGAATATAGTTTATTTAACAGAGAAACAAATTAGTATTTAATTACTTTCTGTTTTTTTAATTATTTTCACTTTTCATGTAAAAAAGTAACTATGTTAAAAATTATTTATGGCGACAATAACTTAAGCTTAGATTGCTTGGATGGATGTTTAGAAGATTGGATAAACACAAGAGTTGCGATCGCTGTGCGTAGCGCTACGGGGATTCATATTGAATCTAGTACGGCTTCTTTTCTATTACCGGCAAACTCATCTACCATAGCCCAGGTAGAAAATATACAAGACGCAAATGTAGTGGAATTCTGCCGCTGCGATGCCAAATCACTTGAAGTTGTGTTGAAAGGTATCTGGTTAACATCAGAATTAGAAAGTGAAACAGGTGTATTCGTAACCAAACTCAAGGATGACACTGAATATTTATTGCAGAATATGTTTGAACCTAAATTTTGCCCGGTTTAACTAACTTTATAGTCTAATTTTATAATTAATCATTAAAAATTATTTACAGTCTTGCTGTTCGCGGGACTATGGTACGACTTCCGAATCCCATCTTGAAACTGGTAATAGTCAGTCGTGCCGCCTTTCCCCGAACAGCATCCCCTCTTCAATTTTAAATTTCAGATTGATATTTTCTGTCTCCTCTGGTTTATTTGTGATGAATGCTACTTTAAATAACCGTGCCCAAGAAGTAGCACGGGAAGATTTAGTCATGTTTATTAATGCTTGTTTGTCCTGTACGGGACAGCGAGAATTCTATGATGATGCTTACGGGCAGAAAGTTTCAATTGACTTTTTGCATCAATATATTTTAGGTAATTACCGATTGCTGTACGCCCGTACTTTAGCAGCAGGCATTAATCATTTTAATCAAGCACAAATAATCTTAAATTTATTAGCTACAGGAAAAAATACATCCCACCAACATCGAAAAGAAGAAGGTGCATTGATTGCCTGGGCACTCCAACAACTACCCCCCCAGCGTGCTTGGGGAATATTACAGCAGTTAAGACAGCGGAAAATAAACAACCGTCGCAGTCGTGCAATTGCTCGCGATTACTTAAAATATCGCCGCAATCTTGATTTTGATGCAGTTAAGTATCGTTCTAAGTTAAGAGCCATTGTGACTCACGCGCATCTCCAACTTCAAGGTGAATTAGGTGATTTTCTCTTTCGTAATTGGAAGCAAAAACTATATGAAACAGAATTATTTGAAAACTTCCGTCAAGCTCATTTTAGTCAAGAAGCAGTTTACAAATTACCTTTTACTGTTGCCGAAGGTTTAGCAGTAAAACACAAAATTAAACGCGAAGTCTTCCTATCGCGCATCCAAGAAAGGATGACTTTAAACGAAAAACTGCGTTTCCAAAATGCTGGTGAAGGCGCAAAAATCAATATTGACGTCGATTTAGGTCGTCTTTCTTTAACCAAGCTAGCATTATATATACTTTCCTTACCCGTGGAAACTCGAAAACAGAAGCGAGATATTTTCGATTTAGCTCTAGAAAAATCCGCTCGCAAAACATTAAGCAAAGCACCGATGAAATTGGGAAAAGTAGCGGCAGTCTTGGATTGTAGCTATTCGAGCTATGGTTCTTCCGAAAAGCGTCGTCGTCCTTTGGGTGTGGCTTTAGCTACTCACTATTTATTGAAAACTGCATCTAAAGAATATCAAGACTTTTGGACTCTACCACCTTTAGATGTATTGCAAGTACGTCCAAAAGGACAATCCGATTTAGCAACACCTGTATTAGACGCATTAGAGTGGGGTGCAGATTTAGTCGTAATTGTTTCCGATGGCTGCGAAAACGATCCACCATGCGGTGCGGCTCAAGTATTGCGTGTTTTTCGGCAACGTTTAGACTCAAAAAATCGTACATCTATAGTTCACTGCAATCCAGTTTTCAACTCGGATGATTTTTCTGTACGTTCTTTATGTGCCGATATTCCTACCGTAGGGTTACGAGACGCTGAAGATTTACCAACTATGCTTGGCTTTGCTCAATTTGCCAACGGTTCGGCTTCTTTGTTTGATTTAGAAGATTATTTAGCTCATAGAGTTAATCGTCAATTATCAATAAATAAGTAAGTAAACAAAAATATTTACTGTCATTGCGAGCGAAGCGAAGCAATCCCAGCCCTTGCGATGAGTCGCACATAAAGGTGAACGCTGAATGCTTCATTTCACTTCGTTCCATTCGCAATGACATTGTGTAATTAATTATGTTTAACTACTTATTTAATGATGGTTGAGTAGCTGATAATTGATAATTGATAATTGATTTAAAATGGCACAAAAGAAAAATATACTAACTAATATATCTCTTAAAGGATTAGATATTGCTCCTTCTCAAGTACGTGGTGCGGTAAGAATTTTACCATTATTAAGACGGAATGTACGCGACGATTTACGTTTGATGAAACGTTCTTATAATGACGATTTAACTGTCGTATCTGTAGATAAAAACCTTAATTATTATGCTTATATTCCTCATGGGTTAGTGATGTCTTGGACTGATGACGGTAGTCCGGTGGCAGCTTTGGGAGGACAAATTCAAAAAATAAAACAACAAACAAAATCTGATGGTAAAAACTTAGATTGTGGTTGTACGAGCGTGCGTTTAATGCATCGCATGAGAAAAAAAGAATCCCAGAATCAATTAAGATTTTTACCCCTACATTTAGCAATGGAAGGTTTTCTTTCCATGTTTTTTTCTGGTCCGAATATTGCTTGGAGCGAATACTCTAAATATGCTCTTGCAAATGGTTTAGGTTGTCGTTACGAAACTGCCGTACAAGGACGCGAGATTGCGAAATTGGAAGATGCATTGCGGGTATTTGAAATTCACCCCAAACAGGTGGGGGTATTAATATTTGTAGCAGAAGCTTTAGCATCAGCTTTTGTGGTTCCTACCCCAGAAGATTATCGTTTACTGCATAGGAGTTTATTAGAAGACTTTTATGGTGAATTAATTTATCAATATGGTTTGCTTCACGATACAACTTTTCCTATGGATGTATCTATTAATGAATCAGAAATTAATAGTTTAAAAAGTTTAAGAGCGGCTATTAATAAAATGCGAATGGATTGGGCTTCTTTTCAAGGTTTTATGGCGAGTGGAATTTTAGATAGTCCATGTCAATCTAAAATAGTTTATAATGCTGGGCCATTTAGATTGCAGCGGTTTATTACCAATATAGAGCTTAAAGGTGAAAATCATATTGGAGAAGTTATTACTAGAGAAAACGGAGAATTAGAATATTTAAAATCTTTTCGTTTATCTACCGCGCAAACAAAGCGAGTTTACTTACTAAGTAAATTAGCCGAACACAATTGGAATATTAATGCTACTGCCGAAGCACTCGGAAATAATTATGATAGTTTTGTCCATCGTTTAGAAAAAGCTGGTTTTGGTTATTTATTAAATCAGCAAGTACGCGAACAAGTTCTTAAGAGAAGACGGAAGAAGTAGAATTTGGTAATTGAGAATTGGTAATTGGTAATTGGTAATTGGTAATTGGACATTGGGCATTGGGCTGTACGATACGAATGCTACTAGCTATGTAATAAAAAATTGCCAGAGATTCTATTTTCTCTGACAACTGTATTTGTTTCTCATATATTTTGTGGAAACATTAAAATAAACGTTAGCCTTTGAGTGCTTTTGTAAAATTTCTACGATAAGATTTACTACCAATAAAGCAAGCTGGCCATAACAAAGATAAAGCAAGGCGATTTGTTAAGCTGTTGCTGAAATTAGTTCTTCTAAATCCAGTCCAAAATTTCCAAACACCGCCTACGTAAGCAACAATTAGTAAACCAGCAATGAACCCAGGCATTTTATCTACTCCAAAAAAAAGAATACTCAAATATCATGACTTGGCATAAGAGTCAATAATTACACTCTCATACACTAGTTTAAGGTAGGCTTACCTTTTCTATCCAGTTATATAGAGATGTGGAGATGGGAAGACAAGGGAATAGTTTTTCATACTCCTCAATTATTCCCAATACCCAATGCCCAATTACCAATTACCGATTACCGATGAAAAATCAAACAATATCTTTACGCTTGAGTAATATTAACGCCACAATCAAATAAACTACTGTGTGTAAACCGAGAATTCCCCAATTCAACATTAAATTGTTGAAAGTCGCGTCATAAACTGAAGAAGCGGCAAAAATATCTTCTAATGAAGGTGCCCCTGGAGTGGCTGCCGGTACCATCTCGTTAACGTTAACTAAAGCACCATAAGCACCCATAGACCAACGACTAATAGTCAACCAGCCGAGTTTTCCCGATAATCTTTTTAATTCAAATAAAACCCCTGAAAGAATTATCTGAGGAATCATAATTAAAGGCAGTATGCTATTAGCTTCGTTTTCGTTTTTGACTGCTGCGGAAATCATTAAACTCAAACTAACGCTTGCTAGCAAAGTTAAAAAAGTTGTGATTCCTAAGCCCACCCCCCAAGGTATAAGATTAGATTCTGGCGATTTAAAACCAATTACAACAGTTATAACTATCAATAAAGTTTGTAAAAAAGTTAAACCACCACGAATCAAAACTTTAGAAGTTAAATAAGGCAGCAAACCCAAATTAATCAGCCTTTCCCTGGCATAAATAGCAGATTCTTTGACAATTTCTCTTACCGAACTCGAAAGCCCTACCCAGATACCAATACAGGCAAAGATAAATAATACTTTGAGTGCTAAAGGTCCTTGAGTGATTTCTAAAGGTTCTAACTTACGTAGAGGAGTTTCGTTTCTTAATATCCAAGCCGTTAACGCGATCGCAATTGGCCCGGATATCAAAGCAAATATCCAACTAGCGCTATCTCTAACTACTAATTGGAAGTATCGCTGGCTCAGTAATATCAACTGTTTAAATGGGGATATACCAGTATGAATTTTATCGTTGCTTTTCTTTTTGGTATCTGTACCTGGCTTGAGTAAATTGCCAACGTATTTCTGAAAATAAGCAGAATGCTTGTATCTTTTCGACCAATAATCTACTGTTTCAACTACTTCTTTAGGACTTCCACCTTGGTCTAATTTAATATAAATATCGGAAAAGTACTTTAACTCATTCGACGGCATTTCAAAGTATTTTAACGCTTCCCCCGGAGGTCCGTAATAACATAATTTGCCACCTCTACCCATAAAAGTAATTCTGTCGCAAACTTCAATATTTGCCGTGGCATGAGTAACTAATATCACCGTCCTCCCCTGGTCTGCCAATTCCCGCAGCAACCGCATCATCTCTTTATCTAAACCGGGATCGAGTCCAGAAGTCGGTTCATCAAGAAAAAATAACTTAGGATCGGCTAATAGCTCTACACCAATGCTCACCCGTTTGCGCTGCCCTCCGCTAAGGTTGCGAATAAAGTTGGTTCTAACGTGAGTCAATTTAATTTGGTCGAGAGTTCTTTCTACGACTGCTTTCACCTCAGTATCGGGAGGAAGTCGCAATTTACATGCGTATGCTAAAACTTCCTCTACTCTCAAATCTGGATGTACGATGTCATCTTGGGGTACGTAACCAATCTGAGAACGATAAACAGCCCAATTTCGCCGCAAGTTATCTCCATTGAGATATACCGAACCCGATGTTACTGGTGCAATTCCCAATAATGATTTCATCAAAGTGGATTTACCAGCGCCGCTTCCACCAACCAAAGCTACTAACTGTCCGGTTTCAATAGCTAAGGAAACATCGTCAAGGATTGCCTTTTGAGTTCCGCCTTTGACTTTAACAATCCGTTGTAGCCGATCCACGTCGAGGCGAACTTGACTACCATTATTTAATAATTCTAGGTATTCTTTTGTATAAAGTAACGAAAATGGACCGATTTGTATTTTGCTGCCGTCGGTTAATTTAACCCGTTTAGAAATTCTTTCGCCATTGACAAAAGTACCGTTGCTACTGGAATCTTGGATAAAATAACCGCCTTGACCATCAGGTAAAAGCGTTGTGTGTATGCGAGATACGGTTGGTGCATCCAACTGCATCGAAGCATAATCATCTAGTTTCGTTGCACGTCCTAGCTGTATGGGAGATTGCTTCAAACCTTTAAAAACCAAACGCCGATTGCTGGGAATAGCAACCGGAACATCTCTTGGATGATAGTAGGTTAACTGAATATGGTTGTGAACCGATTGTCCGATTTCAAACTGCAATCCATCTTTTAATAAGTAGCCTGAAGCATCAATGCGATTTCCATTGATAAAAATTCCGTTACGGCTAGGTTTTGTACCTTCACCATCAAAAAGCCGATAAACATTACCTTCTTTTTTTAAAATAGCTTGTTTTCTAGAAAAAACTTCCCAACCAACAGGAACGTCTAAATCAGCCCACTCAAGCCCCCGTCCCAAGCGATGTTCTTCTTCCCTTAGATACAGCCGTAAAATTTGCCCTTGATTGTTTAATTCTAAATAAGGTTGAGGACTTGCAAGCGTTGGTTTGTCAAAGCTATGAGTCATTATATATAGTTTTAGGTTGAATATAAATTATTTAATCGAACCGATATCAATAGATGCATTAGATGCATTCTTTTTGTTAGTCAAAAACAGCTACAACAAGATCTAAATAAGAAAGTTTTCCGTGCAACCTCGAAAACCTACTTGTTTGGTTTTGAACTAAATTTGAAATTATTTGTACGTATTTACTTAAAAAAGCAGATATCGCCTATCTTAGTCAATAGGTATCTTACATTTGGCAATATAGATTTGAGCGAAAGTTAAGTTTGAAAAAGATTTGTAAATTTTGATAATTAAATTTAAATACGCAGCCATTTAAGTTCATTTATAAAAAAGTATTATGTTTATACGTGGGTTTGTGCGATTCGGGTTTTTGATATTAATCGCACTCTTAGGGATAGGATGTAATTCTTCAAAAAGAGTACCAAAAAAAGTGACTCTAGGCTTAGTTAGCTATGGGGAAGAAGATATTTCACTCTATAAATACGAGGGCTTTAAAAACTATATTCAGGCACAAACAAAGTCGATAGTAGAACTAGAACCTGCTTACAACGAATTACAAGCTATCGACCAAATTCATCGCAAGCAATGGGATATCGTGTTTGCACCACCAGGTTTAGCGGCGATCGCCATCGATAAGCAACTTTACAAACCTCTATTTTCAATGGGTGAAGTAAGCAGCAGACAGCGTTCGTTAATAGTAGTCAGAGATGATAGCCCTATTAAGAAAATACCGGATTTGGCAAATAAAACTATAGCTTTGGGTCAAATAGGTTCTGCTGCTGGCTACTATGTTCCTTTATACGATCTCTACGGTTTAACCCTTAGAAATATCCGTTTTGCTCCCACTCCTAAAACAGTACTTCAATGGCTGAATGAAGGTAGCATTGATGCTGGTGCTTTGTCTGAAAAAAACTTTGAAATTTATCGTCGGCAAATTACGGAAACAAAGTTTAGAATCATACATATCAGTCGGTGGATTCCCCCCGGAGTCGTATTGCTATCACCAAATATTGAACGAAATCGGGAACGAGAAGTCCGCGCAATTATGAGTAAAGCCCCAGCAAATATTACATCAGATGCTGGTTATATTCCTAGCGTCAAAATTCCTGAATACAAGCAGTTTATTCAGCTAATTAAAAAAGTTAAACCTTTAGAGGCGCGAACTAAGGAAACACCAGCAGTTTTGTTACCTAAGGAAGATCCAAAAAATAAATTGTCCCACCGTTTTACAAAATTTCCGGAAAAAACCTAGACGTGTGGCGGTGTCGCTCTACCGAGCGACACCGACGGTGGGACAATTTATTACCTGCAAGTCCCTAAGTCTAATGATAAAAAACTTGTATTATCAGAAACATACCTGCATAAAACCAGCTTTTAAACCTAAGAGTTTAATAGACATCTTTGTAAATTCAGTTTTATTCTAGACATCACAGGAGTTTCAAGCTGATTATCGGAGAGGTCTTATATATATATATAATTTTTAGGAGTGAAAAATAAATGTCCGTGCCGCCCCTTAGCAAACCAGAAATAGCTTCTGGGACTCTAATCGATAGTCGATATATCATTCAAGGGATGCTTGGACAAGGTGGGCTTGGGCGGACTTACTTAGCTTATGATACGCGCCGCTTCAACGAACCCTGCGTCGTCAAAGAATTTGCTCCCTTCGGTACTGGTAGCGATGGCATCGAAAAATGTCGCGATTTGTTCAAAAGAGAAGCAAAAATTCTTCATCAATTAGAACATCCCCAAATACCATGCTTTTTAGCTTGTTTTGAAGGAGAAGGTCGGCTGTTCTTAGTACAAGAATATGTTAACGGTAAAACTTATTCGATGCTATTACAAGAACGTCGAGAACAAGGACAAACTTTTTCAGAAAGCGAAGTAATATTTTGGCTAAAAAAGCTATTACCAGTTTTAGAATACGTCCATCAACATCAAGTCATTCACAGAGATATTTCTCCAGATAATATCATGTTACCTGAAGGCGGAAATTTACCCGTGCTGATTGATTTTGGTGTCGGAAAACAAATAGCTCAGTTAAACGAAGCTACTCAAATAAATCAAGCAGGATTTGCTGGTAATATGTCCCTTGTCGGAAAAGTGGGATATGCTCCTAGAGAACAAATTAGTTTGGGTTTGTGTTCTCCTTCGAGTGATATTTATGCGTTAGGCGTAACGGCGGTAGTGTTGCTTACTGGCAGAAATCCGTCACACTTAATGGATAGATATTCATTAAATTGGAACTGGCATATACATACTAATATCAGCGATACTTTCGCCCAGATACTAGATAGAATGTTGGCAGATACGCCTAAAGGGCGATACCAAACAACTAAGGAAGTTCTCACACAACTCGAACAACTTAGTCAATCGCCGGAACTTCCCACGTTAGTTGTACCTGACTCGATTTTAAACTCTACAATTGTGCCATCTCATAGCCAAACCCAAGAAACAGTAGTTAACTCAATTGATAGTCGGGAAAATAGCCATAGTCCAAAACAATTAAATTTACTAAATCCTTCTTTTCTAGAAAACTGTCAGCAACATTTAGCCTATTACATCGGACCAATGGCTAATTTTATCTTAGAAGATGTATTAGCCAAAAATCCCCAAGCAACGCCGCATCAATTTGTAGAATTATTAGCAAGAGAAATTCCTGATTCCCAAACGGCAATGGAATTTACACGGCAGATTTTTACTTAAATTTATTTTTATTAATCACTTTTATATTAAGTAGCAAATTTCATCAAAAAGATTATTCCCTATTCTGATTAGGATTACTATAACTTTTAAGTCTATTCATTGCCATTTCTAAACTTAATTTCATCCTTTTGAATGCTCTGGCAAGATTACCAATTTCGTCATTAGATACTTGGTCAAAATCAACGTCTATATGTCCGGTGCTAACTTCTTCTGCCACGCGGGTAATACGTTTGAGCGGAAGTATAACTTGTCTATTCAAGAATATATTGACTAAGACAATAACTGCTACAAAAACAAGAGATACAATACCAATAATTACTACAAATGATTTATTCGCTTTTTGAATAACTCTATCAGCTGGTACTGAAATCACTTGAGCGCCGATTATTTCATTGAGTTTCCACCCAAATCCATGAGCAGTACCGTAACGCTCAATCATGCTTGGAGGCGCGACATCAACTGTACTATGACACTGCAAACAACTCTTTTGCGTTACTTTTAAAGGACGAGCAATATAGAAAATATCTCCACTCAGAAGCGAACGAAAACCGCTCATTTCTGTTTTTTTCTGATTCTGGAAACGTTCTATAATCTTGGTTTCAAAATCATCAGCTTTATCTCGAAGATTAGTTGGATTAAGTGTTGCTTCTTTATAAAAAAAGTCTTTATAGTCTCCTTTTTGCCGAAGATTTTCAAATACCTCTCTAGCTGAATAAGCAGGTACGCTTTGAGGTAAAAAACTTATTGCTAATTTCTCTTGCAACTCTGGATTGATTTGAGTACTCGTGTAATTACGAACCGAATTCATCGTTTCCATCAAAATTAAAGCCGTATTCGTAACCTGCCGTTTAGCATTTTGTCTAAGCACAAAAGATAGAGCTAATCCGCTTACGCTAACACCAAGAATCAAGACTATCAGCAGTAAAACTGTAAATTTTTGTTTGAGTTGTAATTTTTTCAACATAATCTTAAGCTTTTTATACTTTTGTAAAAATATTTAATTCCGATACAAGTATGTAGACTGTAGATAATATGAATTGCTACAGAGCTACATTTAAATATTCTTAATCGTGCTTGAATGTATTTTTAATTACCTTAGATTTTCTCCTAGCCAGCAACTATAAGCTTTATCAAAATAATTTTTTGATACTAAGAGTTAATTATTTATCAAATTCTAATATGTCACTAAGTAGTAGGGTATTTTTTTATATTTAAGTAAGATTTATCGGATGTATCTAACTATATCGGGTTTATTAAGGATAATAAATCAAGAAAGGTTAATTTTTTCTTGTTTCGTCTTTATATTTATACAAATCTAGAATTTACGCAAAGATAACTTCATTGTGTCATTATCAGCGACAGCTTAGCGCAGTATCTCTTAAACGGAGATAGTAATCTTACAAAACGCTCTTTATTGCTTCCCTGCATTTTCTTGCTATCACTATTTTGCTTTGCATAAATGCTGACATATTAGGATGACAAAGGTATAAAGTTTGATTGATATTTGATTGATGTTTGATTGATTTACCCGCTCTTGATTAAATATTCAGATCCAAATATAAAAATTATGCAAAAATAAATACCAGTAACTACTAGTTTTTACTAATGGTTTGGCAGCGGGGAAAAAAGTTATTTGGCGATCGCTACATAATTGAAAATATTCTCGGTGAAGGCGGAATGGGTATAACCTATCTTGCTAAAAAACAAAGTGGCGAATTGCGAGTTATCAAAACTCTTCGAGAAGATATTCTTGAACATCCTGCTTGGAAACCATATGAGAATAAAATATTACAAGACTTTCGCGATGAAGCCGTAAGATTAGCTGTATGTCGCCACCCTCATATAGTTGAAATCAAAACAATTTTCGATCAAGAAAATTTGCCTTGTATGGCGATGGAATACATAGAAGGCACAGATTTAGGCAAATATTTACGGCGAATGGGGGTATTATCTGAAGCAGAAGCGCTACTATACATTCACCAAATTGGCGATGCTTTGGAAGTAATTCATCGTCGAGGTTTGCTGCATCGAGATATCAAGCCTGGTAACATTATTATTCGCCAAGGAAAATCGGAAGCGGTATTAATTGACTTTGGTATAGCTAGGGAATTTATTCCCAACGAAGTGCAAAAACATACAGTTTATCGCACTCCCGGTTTTGCACCACCAGAACAATACCAAATTTCAGCACTACGGGGAGAGTTTATTGATGTTTACGCTTTGGCAGCTACTTTGTATACCATTATTACGGGAATTATTCCTCCAGCTGCGGAAGATAGAGGTAAAAACACTTTACTAAAACCACCACAAGATTTAAATCCCCATATCAGCGATAGAACAAATCAAGCAATAATGCGCGGAATGGCGCTAAATTCTAAATATCGTCCGCAATCAGTACAGGAGTGGTTGCAGTTACTCGAAAAACCAACCCATGAAAATAAAATATTAGCAACAGTACCTCCAACGCAAATTGTTACCTCTCCCCGTCCATCCTTACTTCTCTACCGATGGAAATGCGTAAATACCCTTGAAGCAGATACCAGCATGGTTCATGCAGTTACTATCAGTCCCGACGGTAAAATTTTTGCTAGTGGCAGCGATAAAACTATCAAATTATGGGATTTGGAAAGCGGAAAACAGTTGCGTCAGCTAGGAGGTTGGTTTTCTTCACATTCAGGCATAGTTGATAGCCTTGCATTTAGTGGCGATGGAGAAGTTATTGTTAGTGGTAGTTGGGATGAGACAATCAAATTATGGTCTGTAAGTACGGGTAGACAAATTCGGACTTTAAAAGGTCACAATAGCTCTGTAAATACCCTTGCTTTTAGCCCAGACAATCAACTTCTAGCAAGCGGTAGCCTTGATTGTACAATCAAACTCTGGCACATAATAACCGGGCGAGAAGTTGGCAATTTGACAGGACATTCCGCTTCAATTAACGCGGTTGCATGGAGTCCAGACGGACAGTTTTTAGCTAGTGCTAGTGCTGATTGCACGATCAAAATATGGCAAGCTACGGGTAGAGAAATTCACACTTTGTATGGTCATTCTTTATTCGTTAACTCCATCGCCTACAGTCAAGATGGGACAATGTTAGTCAGTGGCAGTTCTGATAATACTATTAAGGTGTGGCAAGCGAGTACGGGTGAAGAAATTCGTACTTTGAAAGGTCACTCTAATGCGGTTTGGACGGTGGCATTAAGTCCAGATAGACAATTTATTGTTAGCGGTAGTTGGGATAAAACAATCAAAATTTGGCTTCTGAGTACGGGTAAAGAAATTTGTACTTTAAAAGGTCACTCTAATTACGTTCGCTCAGTTGACATAAGTCACAACGGACAGACTTTAGTTAGCGGTAGTGATGACTATACTATTAAGATTTGGCAGCAGCATTAGTTTGAGAATAACCAAAAAATTGGTAGTTATTAGTCAAAAATTAGGATTTCTAGACTGTTGGCTTGTTAATTGTAGCTGGTAGCCAATAACTGATAACTATCCGCCGATCACTGTCTCTAGATAGACATCCGATTTGGCAAAAATTGTGAGAATAAATCACGTAAACAGTTAAATCTCACACTTTGCTTTATGAATTTTGGTATTTTCGATATATTTTGGATTTTTCTACTGCTTTCTTCCATACAACCGATTTGGCAAAAGCGTAAAATGGAGTATCGTCGCTTCAATAGTATCGATCAGTTTCAGCAAAAACGTAAAAGTCGGGTAATTCTACTCATTCATCGCCAAGAGTCTATCAGTTTCTTAGGAGTGCCAATTTCACGCTACATTACTATCGAAGATTCGGAAAAAATTCTTCGGGCAATTCGTTTGACTCCACCAGATGTTCCAATTGATTTAATTTTGCATACTCCTGGTGGTTTGGTTTTAGCAACCGAGCAAATAGCTAGAGCTTTAATTCGCCATCAAGCCAAGGTTACCGTTTTTGTACCCCATTATGCGATGAGTGGAGGTACAATGCTGGCTCTTGCAGCCGATGAGATTGTTATGGACGAAAACGCGGTTCTAGGGCCAGTAGATCCCCAACTTGGTAATTATCCAGCTGCAAGTATCATTAAAGTTGTTGAAGATAAACCTATCGGTGAAGTTGACGACCAAACCTTGATTATGGCTGATTTATCGCGCAAAGCCATCAACCAAGTACAGCGCTTCGTCAGGACTTTACTTCAAGATTGCATTCCCAAACAAAAAGTGAAACCGGAAAATATTGAAAACATTGTTAAGGCTTTGACAAGCGGACAAGTAACCCACGATTACCCAGTAACAGTAGAAGAAGCAACGGAAATGGGGCTGCCCATTACTGTTGGACTGCCCCGAACTGTCTACGACCTGATGGAGTTGTACCCGCAACCACAAGGTGGAAGACCTTCGGTGCAGTACATCCCAATGCCTTATGATGACCGTCGTCCCCTGCTTCCGGTTCCCAAAGGTAGACCGATGGAAGAGCCAAACGGTTAAGAAGATAGCTGCGTAGTAGGGAGAGTCGCGAGTCACGAGTTGGTAATTTACTTGCGACTTGCTACTCATTTGCAACTATTTACGATGACCTATGTCCCATTGCCAATACTTCTATGGTGATTCGGTGGGTGTAGGTACTGTTGAGCCACTCCGCGCAATAAATTGACGCGGATTCAGGCATAGCCATCTAACTTTTCACCGCTTTTGTGGTTATCTGGTTAGAGGTTAGCACTTGGGTGGACAACTGCTCAGAGGAACTATGGTAGTTCTTGCGTTCGGACGCGCCTACTTGCCTTGCAGTTTGTTGATATTGCCGAAGCTCGGTGGGGGAAACTTCCCCCACCAGACTTCGCTTCCATGCGTCCACTAAGAGCGGCTCCGCCCTTGGATACTCGCGTAGAGCATCTTGCAATGAAAGCTGATCGCCATACACGTATCTACTCAGAAATGCGGAGAACAAGTCACGATGCATTGTAACCCCGGTAACATCTCGATGAACTCGCTCTGAGAGAGATTTTTTTTATGCGAGTGCCATCAAGGTGGGTTTGTGAGAGTGCTGTTGTCTGAGTAGAAAACTGGAGAAAACAACCGCCAGCATTTTCGGCTTTGCGTTTGATTTCTGATTGAAAAAAGCCAGGAGACTTAGCAGCTATCGCTTTTCCATAACGCTTCTGCCATCCCTTGATACTAACTTTTTCAGTTTTGATTTCGTTGCCATGCCGTAAGATTTCATTTACAAGCCTACGGTTCTGGCACTTAGCATAACTTGCCTTGCGTCGTTCAAGCTCTGCTTTGTGGAGAGCAAGTGTGCGATAATTCTTTGTCCTTTTCCACGGTCTTCTACCTTTTAGAACCTTACCCTTCTTTGTGACGACTCGGTTTCCAACTTTCTTATCAAAGTCAGGCTCAAAATTATCAGGATTGTTGCTCCTCATTGAGCGCTGCATTTTACGCTGTAAGACTTTAATCTCGCGCTCATAGGTAGGAACCTTATCAGCAAAAGGTAGGAGTCCTGCTTGTTCGTCAGCCACAAAGGCTACATTGGAAATGTTAACGTCAAGTCCTACTACGCCTTTAGTTACGTAGTTTTGTGGCTTTTGATATGGTAAACCTTCGTTTACAAGCTGTACAAACCAGCGCTTTTTACCGTTTAAGTTGCGCCAGAGAAGACGGCAGTATTTTATCTTGGAGCGGAGTCCATGAGTTACAACTCGATTGCTCCAATCAATGATTGGCTCTAAAGTAAGTCCACACCATTGTACTTGTTCTTCCTTCCAGCAAAGTCCTTGTTTGTTTGACTTTCCTTCAACTGAGCGAAAGCGAGAGGGGACTTTAAATCGCACCTTACTACTTAGACCCAAGAGTATCTTATGAGCAGCTTGAAATGCTCTAGTAGCAAGTCTTTGTTGCGTGTTGGAATCAACGTTCTTGGCTATCCACTTACTTTGTTTGGCGGTAACAGTTGCAAAGCGATGGAGACTATACTCATTAAATTGAGCGCCATCTCTTGCCTGCTTAAATAGCTCCCGTCGCTCCTTTTTCTTAGTTTTACTGAGTTCTCTTGCTCTTAGGTATGGCGTAGACTTCCTTACTCGCTCAAGTCTTCTTAATGCTTCGTTAAGACAAGCATTGTAGAGTTGACGTGCTGCTTGAAAACGCGCTTCAAGCTTACGTTCTAAGAAGCTGTCAACTACCAAGGGAACTTCTGTGATGAACGAGGACGTTTTTGCTTTCGTCATACCTAGTAACGCTTTTTCTCTCAACCTATAAAAATAGTATCTTGCTATACTATTTTTGTCAACAGGTAGTGGCTATATACAATTCTTTATGAAACCTGTAACTAAGCAATTAGCCAGTAGGGAGTACCGTCATAATAATCACTCAGTTGGGAGTGCAACGGTTCATTTGGTCTGGATACCGAAGCGGCGAAAGCCGGTATTAGTGGGAGAGGTTAAGCAGCGACTCTACCAGATTCTGACTGAAGTTACTGCTGAGAAGGGGTGGTTCATTAAGGCGCTAGAGATTGCACCAGACCACGTACATATGTTGGTAGAACACGACCCAAGTACAGCAATTAACCAAATCGTAAAGGCATTAAAAGGCAGGTCGAGCAGAATTTTACGCAAGGAGTTTCCGCACTTGTTAAAAATCCCCGCTTTGTGGACTCATGCGTACTTTTATGACACTACCGGCAAGGTAAGTAGTGCCGTCATTCAAGACTATATTAACGACCCACATCATTACTAAACTAATGGCGAATAAATTCGCCCGTGTCGAATTTCCGCCCCGATTTAAAAATACGGGGCTACCATTCTCCCGCTACTTTTTCGGTGTCGCTTCCTCTTCGTCATCAGGCGATGGGGTAGGAGTTGGCGAGGGTATAACAGGAGTTGGAGTAACTTCCGGGGTTGCTGTTGGTGATGGTGTCGGGTTTGGTGTATCGGTTGGTGTTGGTATTGGCGTTACTTCTGGTGTCGGTTCTGGTGTCGGGGTTGGCGTTGGTGTTACTTCCGGTATCACAGGAGTTGGGGTAACTTCTGGAGTTGCTGTTGGTGATGGTGTCGGTTCTGGTGTCGGTTCCGATGTCGGGGTTGGCGTTGGTGTTGCTTCTGGTGCTGGTTGCCCTTGGTTATCTGTTGCTTGCTCATTTAGTCTTTGTCGTAAAGCTAAATCGGCGATTCCACTTTGTTCGAGTTCTAACTGCTCCTGATACTTCTTAACTACTTCTTGCGTTCTTGGCCCGTAAAATTGATTGAGAGTTAACTTAGGGTCAGGATTAGCGACCAAATTTAAGTTGTACTTGAGAATTTTAACAATTTCGGCTGCATGATTCTGAGTTTTTGGTCCTGCGATACCATCAACTCCTAATTTGTATCCTCGCTGAAATTCGCTGATTGCTTTTTTTGTTTGAGCATCTGTCAAAGGCGCTTCCGAAACTCTCACGTTGTATCCCAATCCGTACAAAACGGAACGAAATTCTCGTGGAGTATAATTACGCTGACGAGCGGCAAAAACTGTATTTGAAACGGCTACACCACTGACAATTATGCAGGTAGCCACTACACTGATATTCTTATTGCTAAACTCACACCACATGATTAAAACTCCGAGTCATTAAAATCGGCAGTATCTTTAAGCCGTACAGCTGCATTTTAAATTTATTTAAGCTATTTTTATCAGTTTTTCCTTAATTATTAATCATTTTTTTCTTAATCAAATTTTTTTGTAATTATTTGAAATGCATAGCTATAAATAATTTTGTCATCTTCCTATAGATGTATCTTGAAATCTGGTATAAATAGTTTATTTTTTTTGCAATACGTATTATTTAAGTGATGCAAAATACACATAGTCAGATGCATTTTACCTTGTAATAAATATTCTAGAATCATCGATAAAGATTAAATATAATACTTTACGTCAAATACAAAATATGTGGAAGCACTGAATCAAAATGATAAATAGAAAACCTATAAAAAAGAAAAACCTTTGGTTTGAAAGATTAATAGCACTTACGGCCACGATCAATTTAGGATTGGTATTTTTTAACATAACTTACATTGGATGGCGTGATTTTTATTTACGTAGCTTGCCGTTTATTCAAGAAATATATGACCCGATTAAAGGAATTGAACCACATAGGGAAACTGAAAATTATTTGAGAACTATAGAAGAATTAGAATCTCTTGTTGGGGAAACAGAACAATTATCAGCAGAATCGGTAGAAAAGTTAGAAGAATTACGCAACTTGAGCGTAGAGATGATAGAGAATAATCCATTTGCAGCAGTTTCAAAAAGCGGTACTCTGGAGAAAATCAAAAATAGAATGCGCGAACATCTAGATAATGAATCTTCAAAACGTGCTTTTTCCACTTTTTGGACTCAAGAATATTTGTTGCGACAGGGTTTAGATAAAGAGTTAAAATTTTTTAATCAAAAAATTAAACCATTAATAGCCACTAATTATTATCGAAGCATTGGTGAAAATGGGGAATTTATAGATCTATTTTGGATTATTGATTTACCATTCGTAATTTTATTTGTATTCATATTATTGGCACGTAGTTATTATGTAAAACGCCGCCATCCTGGATTTAGCTGGTTAAATGCGATTTTATGGCACTGGTACGATTTATTTTTAGTCCTACCCTTTTGGCGTTGGTTGCGAACCATACCTGTATTATTTCGTTTAGAAAAAGCAGAGTTATTAAATTTACAAAGCCTGCGGCATCAAGCTCAACAAGGAATTGTAGCTAATTTTGCTGAAGAAATAACTCAAATAGTAGTAGTACGAGTCATAAATCAAACTCAAAGTTCAGTCAGAAGAGGAGACTTGACTCGCTGGCTGCAACAAAGTCAAACCTTGAGTCCTTATGTAGATATTAACAATGTCAATGAAATAGAAGCCTTAGGGGGAATTTTTGTACAAACGATTATTCACCAAGTAATGCCAAAAATCCAACCGGAAATAATTGCACTTTTACAACACAATATAGATAGCGCCTTTAACCAATCTCCTATTTATCGAAATTTCCGCAATCTGCCCGGATTTGAGCAAATGCAAACTCAGTTAAGCCAACAATTAGCAACGAGCATTGCGACAAATCTGTATCAAGCATTGGTTTCGGCAGCAGAAGATCCGGTTTCGGCGGAACTCTCAAGCCAATTAGTAAAACGCTTCAGTGAATCTTTGACTACCGAAATTCAAAAAAAGCAAGTACTCTCAGAAATACAAAAGTTATTAATCGACTTCTTGGAAGAAATCAAAATTAATTACGTTCAAAGGCTATCAGAAGAAGATGTGGAGCAAATTCTCGAACAAACAAGAAATTTATATTCAGGAGTGCCTGTTCCCTTATTAGCAGACACGAGAATTAGCCAGAAAGCTTATCCTTATCAAACTAGAAACGAGTAATTGTACATTTTTTGCTGCAAGCATTTTGAAAAAATGCGCTAAACTCAAATTAGGGACGAGCTATTTTACAGCTCGTTGCAAGACTTCTTGGAAGATATTGTTATTGCAGGGAGTGGGTGATTGCCCACTTTTTTTGTTGGAATTGCCACATGACTCATCCTTTAGTTCCCCAAATCGTTGACTTAGCAACACCAGTAGCAGAAGACCTTGAACTAGAGGTCGTTAAAGTGGTTTTTCATACCAATCAAAGCCCGCCAGTATTGCGAGTAGACATCCGCAATCCTCTAACGGATACTAGTTTGAATGATTGCGAGCGTATGAGCCGTAATTTAGAAGCAAGTTTGGATGCAGCTTCAATAATTCCGGATGCCTATGTATTGGAAGTGTCTAGCCCTGGTATTCCCCAGCAATTGCAAACTGACCGGGAATTCATTTCTTTTAAAGGATTCCCGGTTAAAATTTGCACTTCTTCACCCCATCAAGGACACTCCGAATTAAATGGTAAACTGGTTCGCCGAGATGAAAAAAGCGTTTACTTAAATAAAAAGGGTCGCGTAATCGAAATTCCCCGTTCAAAAATTACTTACGTGCAATTAGACGAAGAACGCGATTAAATAGGGAGACTAATTCAAACCAGGACTGCTTCTTACTTTTTGCGGACGTGAAGAAGAGCGGTTTTTTTGCTAAAAGAGCGAAGTAATTAATGGTTAAGACAGATTGTTCTATCAATAATTAACCATTCTTTTTAGCAATCAGCCGTAAATTTTTTGCACACCGCCTATTTATTATCTCTAAATAAGGTATTTTTGCGATTTTTAAGGAGAACGATGTATGTCAATGCTTAAACTACTTGGATTAAAAGAATTGATTGAAAGTATAAGTCGAGAGCGGAATTTACCGCGTCTCGCCGTGCAATCGGCAATTCGAGAAGCACTGCTTAAAGGCTACGAGCGCTATCGTCGCGCTCAAAATTTAGACCGCAAACAATTTGATGAAGATTACTTTGAAAATTTTGAAGTAGAACTTGATATTGATGACGAAGGATTTCGCGTTGTTTCTACTAAAACTATAGTTGAAGAAGTCATAAATTCCGACCATCAGATTGCCCTTGGGGACGTTCAAGAAATCGTAGACGAACTTGGTGATGATGCAGCGCAACTTGTAGGACAAGAAGTAGTTGTAGATGTAACCCCCGATAAAAAAGAATTTGGTCGCATGGCAGCGATGCAAACTAAACAAGTGCTATCGCAAAAACTGCGCGACCAGCAGCGACAATTAATTCAGGAAGAGTTTCAAGATTTAGAAGCAACAGTACTGCAAGCAAGAGTATTGCGGTTTGAAAGACAATCGGTGATTATGGCTGTGACCAGTGGGTTTGGTCAGCCAGAAGTAGAAGCAGAATTACCCAAACGCGAGCAACTGCCCAATGATAATTACCGTATTGGCTCCACTTTTAGAGTGTATCTGAAAAAGGTTTCTCGGGGTCAACAGCGAGGACCGCAATTGCTTGTTTCTAGAGCCGATGCCGGTTTAGTTGTGTATCTGTTTGCCAACGAAGTGCCGGAAATTGAAGACGAAGTAGTACGAATTGTTGCCGTTGCCCGCGAAGCCAATCCTCCTTCTTCTTACGTCGGACCTAGAACAAAAATAGCTGTAGATACTTTAGACCGCGACGTTGACCCAGTTGGTGCTTGTATTGGAGCCAGAGGTTCAAGAATTCAAGTAGTAGTCAACGAATTACGCGGTGAAAAAATAGACGTGATTCGTTGGTCACCAGATCCGGCTACCTATATTGCTAACGCTTTAAGTCCAGCACGGGTAGATGATGTGCGATTAATGGACCCAGAAACGAGACAAACTCATGTACTCGTAGCTGAGGACCAACTCAGTTTAGCAATAGGTAAAGAAGGACAAAACGTTCGTTTAGCTGCTAGACTTACTGGTTGGAAAATAGACATTAAGGATAAAGCGAAGTACGATTTTGAAGCAGAAGATACAAAATTTGCAGCAGCAAGGGCACAACACGCAGCAGAACTTGAAGAACTCGAAGAACTTGAAGAACTCGAAGCCGAAAAATTAGCAGAAGACAAGTTAGATTTAGATAATCAGCCAATTAATTCAGAATTACCAAAAACTTCATTAGATGAAAACGAGGAGGAATTTGAGTCCGAGAATCCAATTATGTATTAGTTGAAATTTTGATGGTGAGAATTGAAACCGAATAGTTAATTAAAATGAAACCAAATTGGAGGCGTTGTATTAGTTGTCGAAAAGTCAGTTTAAAAAGTGAGTTTTGGCGGATTGTCCGCGTCTTTCCTTCAGGAAAGGTACAATTAGATCGGGGTATGGGGCGTTCTGCCTATATTTGTCCGAATTCAACTTGCCTTAGCCTTGCTCAAAAAAAAAATAAACTAGGACGGGCATTACGTGCACCAGTTCCAGAAATGCTGTATAAGACACTGTGGCAGCAATTAACAATCAAGTAACTTTTTACTTGTTCAAATTATATAGGGGGTAATTTTAACAAATATTAAAGCTGAGATTCGCCTATAAATGCGTTCTTCTATGTTGATTAAATTATCTTTTAGTAAAGAAGGTTAGTGCCACGGAGAATTATAAATGAGTATTGACACATGGCTCTTTTGGGCAATAAGGGCACTTGCTTTTACTGAGTTATTGTAGGCAGATCGTGTGTTAAACCCGACAAAAACATCAACAAAACAAAAAACTAAATATCGGCATTTGGTAACGCCCATGCAGCCCATTCGAGCATTAACCAATATGGCGACAGGCTTGGAGATGCCAGCTTTCCAATGGACACATCTCTCTTTCCTTTTTCAGGAGGAACCTTTTCAAATTGAAAATGGCAACCGTTACACAGTTTTCAAAGGATGGAGATGTCGCAAAAGCTGGCAGCCATCCGTTAAAACTGTAAATTATAGGGGAAGAGTGGATGAACAACGGCAAAGTCAGAATTTACGAATTATCAAAGGAATTGAATTTGGAAAATAAAGAGCTATTAGCAATTTGCGACCAGCTCAACATCGCGGTCAAAAGTCATAGCAGCACTATTACTGAATCGGATGCAGAACGTATTCGTTCGCAAGCAGAAAAACTGACAACAACTTTGGGGTTGTCGAAAGAGCATGGTACAAATAATAAGGGTTCTGCCAACGGTCATAATGCACCCAGCAAACCACAAATATTGGAAATTCGTAGCAAACCAAAGCCACCGAAGAACTCCAGTAGTACTGACTCTGCTTTGCTCTCACCCAATTTAGAAAACCAACAGAGCGCATCTACCGATAGCGCGTCCGCAAAACCTTTTAATTCTTCAGTCTCGCCGAAAGAAACAGTGGCACCAACTGCACCAGTCTCCCCGAATCAGCCCTTGCGCTCTCCAGATAACTCTGTATCCGTTACAAATACGGATAATTCAGCATCCACTCCCTCTTCAGAATCAAATAAAACAGCTTTGAGCAAACAAGAAAAACTAGTTACACCCAAATCTAAACCGGAAAGACCAAATGCACCCGAACTAACTGCGCCGCCAACTAGACCTGCGGCAGCAAACCCAAATTCCGGTTCGGACGATCGCGTCGTTGAAAAACCAATTCTTAAGCGCGATCGCAGTCAATCAAAACCGCCGCAACGCAAGCGGGAACAGAATGCCGAGAAAGCTGAAATATCAGCAGCACCAGCTTCTAAAACCCCGCGTCCGACTTCTGCACCAGTATCAAAAGTAGAAAAGCCGCAGAAGGTCAAGAAAATCTCCCAGGGAGGCGGTGGTTCTTCTGATGTTGCACGTCCGAAAAAGCAAGTACGTCAAGAATCGTCAGCGCCTCCGAGTGTATCGGCGCTTAAACCCCCAGTAAGACCTGCCAAACCGTCGGTTGGCGAATCAACTGATGTTGACGACAATGATGATGATGATGTAGTTGTCGAAGAAGTAGTAGAGCTAAAGCGTCCAACACCACCTCGTTTACCCAGAGGTCAGAAAAAGCGCTCCAAACAAGAGGAGGCTATTGACGAAGCTAAAGAAGCAGCTAAAGCCGCAAAAGCTCCTAAGAATAAACGTCTGAAGCCAATGGTTGAAGACGATTTTGAGGTAGACTTACTTGACGAAGATGAAGCAAATAATGCGATTCAAGCAGCAGTTAGCAATGCTATAGTTCGTCCTCCGAAACCAAAAAGTTCCACACCGAAAGCAGCACCAACACCTGCTGCACCAAGCAAAGTTAAAAAATCCGGTTCTCGCGACCAAAATCGTCGGCGCGGGGGCGGCGGTAATACAGAGGCAGAACCTAAACGTCAGCGTCCTGAAATAATCACGGTTAACGGTCCAATGACCGTACAAGAATTGGCAGATGCTTTGGCAATGCCAGATACAGAAATTGTCAAAATCTTGTTCATGAAGGGTATTGCAGTTAGTATTACCCAGAGTCTTGATACTTCAACAGTCATTATGGTGGCTGAAGAATTAGAAGTATTGGTAGATACTCCAGAACCGGAGGCAGAAGCCCGTAAGGTTACGGAGATGCTGGACTTAGCAGATATGGAAAATCTCCATCATCGTCCACCCGTAGTCACAATTATGGGTCACGTAGACCACGGTAAAACAACTTTACTCGACTCGATTCGTAAAAGTAAGGTGGCTTCTGGAGAAGCTGGAGGTATTACCCAGCACATTGGGGCCTACCATGTAGATATCGAACATGAAGACAAAGAGCATCAAATTGTCTTTTTAGATACCCCCGGTCACGAAGCATTCACGGCAATGCGAGCAAGAGGAGCAAGGGTTACAGATATTGCCATATTGGTAGTAGCTGCCGATGACGGCGTTCGTCCCCAGACAATTGAAGCCATTAAGCACGCTCAAGCTGCGGAAGTGCCAATTATTGTTGCAATCAACAAAATTGATAAAGAAGCGGCACAGCCCGATCGAGTCAAACAAGAGTTGATGCAATATGGTTTGACCTCAGAAGAATGGGGTGGCGAAACAATCATGGTTCCCGTCAGCGCCATTAAAGGGGAAAACTTAAATACGCTCTTAGAAATGATCGTGCTGGTTTCCGAAGTTGAAGACCTGCAAGCGAATCCAGAGCGTTCGGCTAAAGGAACTGTCATTGAAGCTCATTTGGATAAAGCAAAAGGTGCAGTCGCAACCTTGTTAATTCAGAACGGTACCTTACACGTAGGAGATATCCTGGTAGCCGGTTCCGTGTTCGGAAAAGTCCGAGCAATGGTCGATGACAGAGGGGAACGAGTTGAAGAAGCAAGTCCTTCCTTTGCTGTAGAGGTATTGGGTTTAAACGACGTACCCGCAGCAGGTGATGATTTTGAAGTCTTCACCAATGAAAAAGAAGCACGGTTACTTGCCAACGAACGAGCCGAGGTAATACGTCAATCCCGCTTGATGCAGGGAGGGCGCGTCACCTTGACAAGTATTTCAGCACAAGCACAAGAAGGCGAGTTAAAAGAACTCAACTTAATCTTGAAAGCAGACGTGCAGGGTTCGGTCGAAGCTATTTTGGGTTCGCTCAAACAAATCCCGCAAAACGAAATACACATTCGGATGTTGCTATCTGCTCCTGGAGAGGTTACTCAGACAGATATCGACCTAGCCGCAGCCAGTGGTGCAGTAATTATCGGCTTTAACACTACATTTGCTAGTGGTGCGAGACAAGCAGCAGACGAAGCTGGTGTAGATGTACGAGAATACAACATCATCTACAAACTCTTAGAAGACATTCAAGACGCATTAGAAGGTCTGCTAGAACCAGAATTAGTAGAAGAACATTTGGGTCAAGCAGAAGTACGTGCAGTCTTCAAAGTAGGAGGCGGTGCTGTTGCTGGTTGCTACATCCAATCTGGCAAACTGCTTCGTAACTGTAAAGTCAGAGTACGTCGCGGTAATAACTTCGTATTTGAAGGTGCCCTTGATTCCCTCAAGCGGATGAAAGAAGACGTGCGCGAAGTCAACTCCGGTTATGAATGTGGTATTGGCGTTGATAAGTTCAATAGTTGGGAAGAAGGCGACATAATTGAGGGTTATCAAATGGTGACTAAACGTCGCACTCTTGCAATGGCAAGATAGTGAGCAGGCAAAGATATCGCAAAAATCTAATTGGGCAACATAGGTATTTATTACCCCTAGTTGCCTTATTAACATCAAAACCCTTACGCTTGCAAAATATTATTCCAATTAAACTATGTAGAGATTCGGCGCTCAGCTTTTATCTCTACATATTTTTATATCCGTAAAATTCGGTAAAATTATGAATTAAAATTGAGTTTAGTAACAACTGCAACAGAAATATCCGTCAGTTAACCACTAACTTGAAAAAGTATTGCATAAAACTAGAATTTAATTTTTAGGCAATTCTCAGATCGGTTTGGAAAAAAATCAAACGATAAAACAATAAAACAATTAAAAAAAAATAAATTAGATTTAGTTCGTAGTTTTGCTTGTAATAGAAAGCATAGCGAGTGTATTACAGTACGGATAGGACACTATAAGTAATCCCAAGTCAATAAATAAAAATATATTCTGCACAAATTATAAAAGTCAAATCAAAAAGTTAAGCAAAGGATTGATTAATCATGAGTAGTTTTACAGTCAAAAGCGATAGTGGCTTAAAAGGCGATGCCGATATTTGGAATAACTTGAAGCAAGCGATCGCCATTAGTTCAGGTTTTCAACGTTGGCAGATGGAGCGAGTCCATGCGGACAATGCTTTTGAGACATTAAGTTTAGACGAACAAGTACAGCGGTATCTAAGAGAAACTTTAGAAACTTTAGCTTATTAACTGATTGTTAGTTTTCAATTATCAACGAACAATTGCGAAACCAAACTATGAAAGAGCCTTCGCTGTTAATTGTTAATTGATAATTGAATCAAGATTCTTCTTCAGGATTAGAAAATAAACTCGGATCTAAATAATTGATCCGTGAAAGCGGGCTTAAGGCTGCAAGAACTTGAGCGCCGTAGCTACGGTAAATGGCTCGGCTATCTAGCAAAGCCACTATGCCGCTAGAATCTCTTGCAGGAGCTACGGCTCGCTGTAATTCGTTTAATGCTGTAGGTAACAAATACAAGCGGAACCAGTCTTGATGGGAATGCTTGTAGTAAGCAACTCTACCGGCAACCAATGGATCTTCTAAAGATGGTAGAGGTAAAGTGGAAATAATCAACATTTGTGGAGCAGGTAAAACTCTTTGATGTTGCCGCCAAAATTCCCAACCGCAAACTAAAATACCATTTTCATCCAAACAAGTTTTGTCTACCTGTACCCGCGAACCAAATTCAGCAGCCAAAATTGTTCCTAATTGAGATTTGAGCGGTACATCTCCAACTAAGATTACGGTTAAACCTGGTGAAGTTGCACTCAAGCATACTAAAGTGCGAACTTGGTGAATAAACACAGGTTTAAATTCCGGTGTGTTAGGTAAAGGTAATTTATTAGGTATGTAAACTTGAATTGCTTGAGTTTGATTATCATTCGAGAACTTTAAGCAAGTCAGATCGCCTAATCCCAACCGCTGGCGAAATAATGTAGCTTCAGTTTCTGGTTCTAAAGCCGAACCGACTAGTACTACAGGTTGTCGCTGCCAAATTGGCGAGAGAATTTTTCCCAACTCAATTGGGGCACAATGTAGAGAAAATAGACCTTGACGGCGGCTAATAGTAGCCCAGAGTAAAGGAGGAGAAGGTGAAGATTTAGTAGCAGAAAATGTTTCGTGTCTCGTTTTAAATAATTGCCAAAACCTTTTCCAAGTTTCCGGAAGGCTACTTAAATCTAAACTTGAATAAATACGGCATAAAATTTCTTCTTCTGGTTCCGATATCAAGTAACATTCGTAGGGATTTGCAGGATGCTGAAAAATTTCGTGGGTTAATTGCACTCGGAGGGTACGAATTTCCTCAGCCAAGGAAGGATAAGCGAGCATTAACTGCTCCCAATCTTGTGGTTCAATGCTCGCGGTAAGCTGTTCTCTTATCCAATCTTCCAAGTCATCTACACCATCAATAATTGTGGGAATATTTGGGGGAAATTTACTATTAGGACTCAATTGAGCATTTAACCAAGCTTGAGGAGATACTATGAGAATTCCCTGGAAATCTAAAGAGGGAAAAGTATCGCCTACTATAATTGGTTTATTAACTTTTAGCCACTTTTGTAGTCTAGGAATTTCCACTTGTAACAGACGTTGCTGTACTGGTTGAGTCGCGACGATAACCACAGCCCCCTGCCACATTAAAGCCGAAGCCACAAAACTAGTACGATACTGACCTTGATAACCACAAGCCGCTCCCACCTGAATTAAAGCGCTACGCCCTACCCTTAACGCGCGTGCTACCAACCGCGCCATCGTTAAATGGTGTGGCCAAGAAGGTAAACCTGCCTGCGATCGCAGGAAATTATGTAGTGATAAATGAACTTCTGCTTCAATCACGCTCTAAATCCCATACATAGTGATTTTTAGTTGATTCTTTAAACTAATTTTTTAACTTAATTTTTTTAGCCAATTCTTTAAACCCAGTTTTAAACAGTTCTTATCTTTATTTATATTATGTTTTTATTTTGAGAGCGGCAGTCTAAGGTGCCAAATTGCTAAACTACAAACGATTAAACACTTTTTAAATATAGTTCAGACGATTACAAATTATGTAACGTAGCCTTCTTCAAAGAAGTACCTTTGAACCAGATTGTGCCGTTTCTACATTTGTTGTCGCCGAACCTACAACTAATTACCCTGCAATTATGCCAACTTATAAAGGAATTTCCAGCGAAGCTTTCAGACATCCCTTAGATCGTCAAGCCGAAGAAAGCTTAAGAGGTTTACCGGGGTTTGACTTTGTTGCCCGTAAATTCGTGGAATTTGTCTACGAACGTCCGCAATTAATTTATTTAATGGGTAATACCATTGAAGTAGGACCGCGACAATATTCAACTATCTATCAGATATTTCGAGAATGCGTGCGAGATTTGGATATTCACCCAGAACCCAAATTGTTTGTTGAGCAAAATCCCGTTGCCAATAGTTACGCTTTAGGACAGGAGCATCCTTACATCGTTATCAATACGGGAATTTTAGATTTGCTTAACGAAGCCGAAATCAGATCTGTGTTAGCCCACGAGTTGGGACACATTAAGTCTGGTCATACTATTTTAATTCAAATGGCGATGTGGGCGATGAATGCAGCCTCTATTGTCGGAGAACTGACTTTTGGTATTGGTAACATAGTTAGCAGCGGTTTGATTTATGCCTTTTTTGAATGGCGACGCAAAGCCGAGTTAACAGCCGATAGGGCTGCACTATTGGTTACGGATGACTTGAATACGGTTATGTCTTCAATGATGAAAATTTCTGGCGGTAGCAATAAATATGCTAACGAATGCAGTTTGCAAGAATTTATTCGTCAATCGGAAAATTATCAAGCACTTGACGAAGATGGGCTTAATCAAGTGTATAAATTTTTAATGTACAACGGCGCTCAAGGGGTAATGCTCAGTCATCCTTTTCCTGTAGAAAGGCTACATCATCTCAGGAAATGGGCTGTATCTCAAGAATATATGGAAATAAAACAAGGAAATTATGCTAAAGAATCTGACAAGAGTACAGTTGATGTGAAACCGAAAGAAAACCAAAATGACGAAATTGATAAATTGCAGCGAGAAATAGAAAAATTACAAACAGAAATAAATCAAATTAAACGCGAACACTGACTTGTAAACAGAAATAAATTATAAGAATAATTAGAGCAATTAATTAGCAGCATGTGAATCAGAAAAAACCCGGTTTATTAGAAAATCCGGGTTTGTAGACGTGCTAATTGCTTAAGATTTGCTTACTTAATAGACAAAATTAATTATCTAAAATTTTAAATATTGTTTTAGGAGAAGCAATATAATTATTTTTAGTTTCACTGCCTTTTATCGAAGGGCAAGATATTACCTTCAATCGCTTCATTCTCTCCATCGTCTGTAGAAACTGATTCTTCCGCAATTCTTTCCCTATCTGAGTGATTTCTGTCTGAGTTTTCTTCATTTTCTTCGCTCAAATTTTCCAAATTTAAGATAATTTCATTAGAAGGAGGTTTACGTACCAAAGGTAATATCATCTCTTCTAGTTCAAGTTCTAAATCGTCAGGCTCTCTAACACAATCAAATAACTTTTTCGCTTCTTCATAGTCAATAACAAAACTATGAGAAGGATAGTTATAAATTAGATTTTTAATGACTTCAATGCCTTCCGGCTTTAATCTTTGACCATAAGCTAAAGCAATATTCATTAATCTATTCATTTCACCCAATCTTAAGGGGTCAATTTGACTGGGGATTGGAGACAATAAATTTACAGCCATAGAACTTGCAATATCTGCTGCTGTTTTGGTAGTTATCAGCGCTTGAGTTCCAGAAATTAAATTTAACAAATAGCTCTCAAACATTTCAAAAGCTTGCGAGCCAATTACAGACATGGCTTGTTGAATATCTAATACAGACTCGCTTCTAAAGTCATCATCTTTAGTCACTTGGACATCGAGAGGACCTAATTCACCGAAATCAGATATGACAATTTCGTCGGCACCTAATGCCAATAAAGTTCCGGCACTTTTACAGTAGCCAAATACAAATAAACTAAACTTTTTATATTTTCTTTTGATATAGCGGGCAATTCTAAAAGCCGCATCTGGGTCGCCACCATAAGTAGTCATAATTAAGACTACGTTATCTCTTTTAGGTGAGGTTGCTTTAATTTCATTAATTAATTTATCAGCATTAAAATCTGTGATTTCAGCACTATACAGAAAAATATCAGCATCAAGTTCCTCTGCAACAAACTCAATACATCTGATTAACTGCTTTTTGTTTTCCAT

Protein sequences of DBSCAN-SWA_1

>NC_019678|1727397:1759812|1751620_1751941_+|WP_157229258.1|DBSCAN-SWA
MLNPTKTSTKQKTKYRHLVTPMQPIRALTNMATGLEMPAFQWTHLSFLFQEEPFQIENGNRYTVFKGWRCRKSWQPSVKTVNYRGRVDEQRQSQNLRIIKGIEFGK
>NC_019678|1727397:1759812|1743126_1744014_+|WP_015117513.1|protease|DBSCAN-SWA
MNFGIFDIFWIFLLLSSIQPIWQKRKMEYRRFNSIDQFQQKRKSRVILLIHRQESISFLGVPISRYITIEDSEKILRAIRLTPPDVPIDLILHTPGGLVLATEQIARALIRHQAKVTVFVPHYAMSGGTMLALAADEIVMDENAVLGPVDPQLGNYPAASIIKVVEDKPIGEVDDQTLIMADLSRKAINQVQRFVRTLLQDCIPKQKVKPENIENIVKALTSGQVTHDYPVTVEEATEMGLPITVGLPRTVYDLMELYPQPQGGRPSVQYIPMPYDDRRPLLPVPKGRPMEEPNG
>NC_019678|1727397:1759812|1732642_1733827_+|WP_015117506.1|DBSCAN-SWA
MAQKKNILTNISLKGLDIAPSQVRGAVRILPLLRRNVRDDLRLMKRSYNDDLTVVSVDKNLNYYAYIPHGLVMSWTDDGSPVAALGGQIQKIKQQTKSDGKNLDCGCTSVRLMHRMRKKESQNQLRFLPLHLAMEGFLSMFFSGPNIAWSEYSKYALANGLGCRYETAVQGREIAKLEDALRVFEIHPKQVGVLIFVAEALASAFVVPTPEDYRLLHRSLLEDFYGELIYQYGLLHDTTFPMDVSINESEINSLKSLRAAINKMRMDWASFQGFMASGILDSPCQSKIVYNAGPFRLQRFITNIELKGENHIGEVITRENGELEYLKSFRLSTAQTKRVYLLSKLAEHNWNINATAEALGNNYDSFVHRLEKAGFGYLLNQQVREQVLKRRRKK
>NC_019678|1727397:1759812|1741146_1742937_+|WP_015117512.1|DBSCAN-SWA
MVWQRGKKLFGDRYIIENILGEGGMGITYLAKKQSGELRVIKTLREDILEHPAWKPYENKILQDFRDEAVRLAVCRHPHIVEIKTIFDQENLPCMAMEYIEGTDLGKYLRRMGVLSEAEALLYIHQIGDALEVIHRRGLLHRDIKPGNIIIRQGKSEAVLIDFGIAREFIPNEVQKHTVYRTPGFAPPEQYQISALRGEFIDVYALAATLYTIITGIIPPAAEDRGKNTLLKPPQDLNPHISDRTNQAIMRGMALNSKYRPQSVQEWLQLLEKPTHENKILATVPPTQIVTSPRPSLLLYRWKCVNTLEADTSMVHAVTISPDGKIFASGSDKTIKLWDLESGKQLRQLGGWFSSHSGIVDSLAFSGDGEVIVSGSWDETIKLWSVSTGRQIRTLKGHNSSVNTLAFSPDNQLLASGSLDCTIKLWHIITGREVGNLTGHSASINAVAWSPDGQFLASASADCTIKIWQATGREIHTLYGHSLFVNSIAYSQDGTMLVSGSSDNTIKVWQASTGEEIRTLKGHSNAVWTVALSPDRQFIVSGSWDKTIKIWLLSTGKEICTLKGHSNYVRSVDISHNGQTLVSGSDDYTIKIWQQH
>NC_019678|1727397:1759812|1730450_1730816_+|WP_015117504.1|DBSCAN-SWA
MLKIIYGDNNLSLDCLDGCLEDWINTRVAIAVRSATGIHIESSTASFLLPANSSTIAQVENIQDANVVEFCRCDAKSLEVVLKGIWLTSELESETGVFVTKLKDDTEYLLQNMFEPKFCPV
>NC_019678|1727397:1759812|1746333_1747110_-|WP_015117514.1|DBSCAN-SWA
MWCEFSNKNISVVATCIIVSGVAVSNTVFAARQRNYTPREFRSVLYGLGYNVRVSEAPLTDAQTKKAISEFQRGYKLGVDGIAGPKTQNHAAEIVKILKYNLNLVANPDPKLTLNQFYGPRTQEVVKKYQEQLELEQSGIADLALRQRLNEQATDNQGQPAPEATPTPTPTSEPTPEPTPSPTATPEVTPTPVIPEVTPTPTPTPEPTPEVTPIPTPTDTPNPTPSPTATPEVTPTPVIPSPTPTPSPDDEEEATPKK
>NC_019678|1727397:1759812|1737175_1738090_+|WP_015117509.1|DBSCAN-SWA
MFIRGFVRFGFLILIALLGIGCNSSKRVPKKVTLGLVSYGEEDISLYKYEGFKNYIQAQTKSIVELEPAYNELQAIDQIHRKQWDIVFAPPGLAAIAIDKQLYKPLFSMGEVSSRQRSLIVVRDDSPIKKIPDLANKTIALGQIGSAAGYYVPLYDLYGLTLRNIRFAPTPKTVLQWLNEGSIDAGALSEKNFEIYRRQITETKFRIIHISRWIPPGVVLLSPNIERNREREVRAIMSKAPANITSDAGYIPSVKIPEYKQFIQLIKKVKPLEARTKETPAVLLPKEDPKNKLSHRFTKFPEKT
>NC_019678|1727397:1759812|1757695_1758661_+|WP_015117523.1|protease|DBSCAN-SWA
MPTYKGISSEAFRHPLDRQAEESLRGLPGFDFVARKFVEFVYERPQLIYLMGNTIEVGPRQYSTIYQIFRECVRDLDIHPEPKLFVEQNPVANSYALGQEHPYIVINTGILDLLNEAEIRSVLAHELGHIKSGHTILIQMAMWAMNAASIVGELTFGIGNIVSSGLIYAFFEWRRKAELTADRAALLVTDDLNTVMSSMMKISGGSNKYANECSLQEFIRQSENYQALDEDGLNQVYKFLMYNGAQGVMLSHPFPVERLHHLRKWAVSQEYMEIKQGNYAKESDKSTVDVKPKENQNDEIDKLQREIEKLQTEINQIKREH
>NC_019678|1727397:1759812|1755827_1757387_-|WP_015117522.1|DBSCAN-SWA
MIEAEVHLSLHNFLRSQAGLPSWPHHLTMARLVARALRVGRSALIQVGAACGYQGQYRTSFVASALMWQGAVVIVATQPVQQRLLQVEIPRLQKWLKVNKPIIVGDTFPSLDFQGILIVSPQAWLNAQLSPNSKFPPNIPTIIDGVDDLEDWIREQLTASIEPQDWEQLMLAYPSLAEEIRTLRVQLTHEIFQHPANPYECYLISEPEEEILCRIYSSLDLSSLPETWKRFWQLFKTRHETFSATKSSPSPPLLWATISRRQGLFSLHCAPIELGKILSPIWQRQPVVLVGSALEPETEATLFRQRLGLGDLTCLKFSNDNQTQAIQVYIPNKLPLPNTPEFKPVFIHQVRTLVCLSATSPGLTVILVGDVPLKSQLGTILAAEFGSRVQVDKTCLDENGILVCGWEFWRQHQRVLPAPQMLIISTLPLPSLEDPLVAGRVAYYKHSHQDWFRLYLLPTALNELQRAVAPARDSSGIVALLDSRAIYRSYGAQVLAALSPLSRINYLDPSLFSNPEEES
>NC_019678|1727397:1759812|1734002_1734194_-|WP_015117507.1|DBSCAN-SWA
MPGFIAGLLIVAYVGGVWKFWTGFRRTNFSNSLTNRLALSLLWPACFIGSKSYRRNFTKALKG
>NC_019678|1727397:1759812|1734408_1736838_-|WP_015117508.1|DBSCAN-SWA
MTHSFDKPTLASPQPYLELNNQGQILRLYLREEEHRLGRGLEWADLDVPVGWEVFSRKQAILKKEGNVYRLFDGEGTKPSRNGIFINGNRIDASGYLLKDGLQFEIGQSVHNHIQLTYYHPRDVPVAIPSNRRLVFKGLKQSPIQLGRATKLDDYASMQLDAPTVSRIHTTLLPDGQGGYFIQDSSSNGTFVNGERISKRVKLTDGSKIQIGPFSLLYTKEYLELLNNGSQVRLDVDRLQRIVKVKGGTQKAILDDVSLAIETGQLVALVGGSGAGKSTLMKSLLGIAPVTSGSVYLNGDNLRRNWAVYRSQIGYVPQDDIVHPDLRVEEVLAYACKLRLPPDTEVKAVVERTLDQIKLTHVRTNFIRNLSGGQRKRVSIGVELLADPKLFFLDEPTSGLDPGLDKEMMRLLRELADQGRTVILVTHATANIEVCDRITFMGRGGKLCYYGPPGEALKYFEMPSNELKYFSDIYIKLDQGGSPKEVVETVDYWSKRYKHSAYFQKYVGNLLKPGTDTKKKSNDKIHTGISPFKQLILLSQRYFQLVVRDSASWIFALISGPIAIALTAWILRNETPLRKLEPLEITQGPLALKVLFIFACIGIWVGLSSSVREIVKESAIYARERLINLGLLPYLTSKVLIRGGLTFLQTLLIVITVVIGFKSPESNLIPWGVGLGITTFLTLLASVSLSLMISAAVKNENEANSILPLIMIPQIILSGVLFELKRLSGKLGWLTISRWSMGAYGALVNVNEMVPAATPGAPSLEDIFAASSVYDATFNNLMLNWGILGLHTVVYLIVALILLKRKDIV
>NC_019678|1727397:1759812|1745841_1746261_+|WP_015117032.1|transposase|DBSCAN-SWA
MKPVTKQLASREYRHNNHSVGSATVHLVWIPKRRKPVLVGEVKQRLYQILTEVTAEKGWFIKALEIAPDHVHMLVEHDPSTAINQIVKALKGRSSRILRKEFPHLLKIPALWTHAYFYDTTGKVSSAVIQDYINDPHHY
>NC_019678|1727397:1759812|1728357_1728639_-|WP_015117501.1|protease|DBSCAN-SWA
MSVETIEKRSTTRKHAPRYRVLLHNDDYNAMEYVVEILITTVPSLSQPQAVSIMMEAHTNGFALVITCAQEHAEFYSETLKTHGLNSTIEPED
>NC_019678|1727397:1759812|1729438_1729696_-|WP_015117503.1|DBSCAN-SWA
MLHNNNGETLSIYEWLSRAGFQNSDVFKMEPELIRHLHKQWFVYRELVQTFMSETGCSDPSEFEINHPYRTPQVPQRNPSYSQIA
>NC_019678|1727397:1759812|1751882_1755026_+|WP_015117520.1|DBSCAN-SWA
MNNGKVRIYELSKELNLENKELLAICDQLNIAVKSHSSTITESDAERIRSQAEKLTTTLGLSKEHGTNNKGSANGHNAPSKPQILEIRSKPKPPKNSSSTDSALLSPNLENQQSASTDSASAKPFNSSVSPKETVAPTAPVSPNQPLRSPDNSVSVTNTDNSASTPSSESNKTALSKQEKLVTPKSKPERPNAPELTAPPTRPAAANPNSGSDDRVVEKPILKRDRSQSKPPQRKREQNAEKAEISAAPASKTPRPTSAPVSKVEKPQKVKKISQGGGGSSDVARPKKQVRQESSAPPSVSALKPPVRPAKPSVGESTDVDDNDDDDVVVEEVVELKRPTPPRLPRGQKKRSKQEEAIDEAKEAAKAAKAPKNKRLKPMVEDDFEVDLLDEDEANNAIQAAVSNAIVRPPKPKSSTPKAAPTPAAPSKVKKSGSRDQNRRRGGGGNTEAEPKRQRPEIITVNGPMTVQELADALAMPDTEIVKILFMKGIAVSITQSLDTSTVIMVAEELEVLVDTPEPEAEARKVTEMLDLADMENLHHRPPVVTIMGHVDHGKTTLLDSIRKSKVASGEAGGITQHIGAYHVDIEHEDKEHQIVFLDTPGHEAFTAMRARGARVTDIAILVVAADDGVRPQTIEAIKHAQAAEVPIIVAINKIDKEAAQPDRVKQELMQYGLTSEEWGGETIMVPVSAIKGENLNTLLEMIVLVSEVEDLQANPERSAKGTVIEAHLDKAKGAVATLLIQNGTLHVGDILVAGSVFGKVRAMVDDRGERVEEASPSFAVEVLGLNDVPAAGDDFEVFTNEKEARLLANERAEVIRQSRLMQGGRVTLTSISAQAQEGELKELNLILKADVQGSVEAILGSLKQIPQNEIHIRMLLSAPGEVTQTDIDLAAASGAVIIGFNTTFASGARQAADEAGVDVREYNIIYKLLEDIQDALEGLLEPELVEEHLGQAEVRAVFKVGGGAVAGCYIQSGKLLRNCKVRVRRGNNFVFEGALDSLKRMKEDVREVNSGYECGIGVDKFNSWEEGDIIEGYQMVTKRRTLAMAR
>NC_019678|1727397:1759812|1749078_1749543_+|WP_015117516.1|DBSCAN-SWA
MTHPLVPQIVDLATPVAEDLELEVVKVVFHTNQSPPVLRVDIRNPLTDTSLNDCERMSRNLEASLDAASIIPDAYVLEVSSPGIPQQLQTDREFISFKGFPVKICTSSPHQGHSELNGKLVRRDEKSVYLNKKGRVIEIPRSKITYVQLDEERD
>NC_019678|1727397:1759812|1731012_1732443_+|WP_015117505.1|DBSCAN-SWA
MNATLNNRAQEVAREDLVMFINACLSCTGQREFYDDAYGQKVSIDFLHQYILGNYRLLYARTLAAGINHFNQAQIILNLLATGKNTSHQHRKEEGALIAWALQQLPPQRAWGILQQLRQRKINNRRSRAIARDYLKYRRNLDFDAVKYRSKLRAIVTHAHLQLQGELGDFLFRNWKQKLYETELFENFRQAHFSQEAVYKLPFTVAEGLAVKHKIKREVFLSRIQERMTLNEKLRFQNAGEGAKINIDVDLGRLSLTKLALYILSLPVETRKQKRDIFDLALEKSARKTLSKAPMKLGKVAAVLDCSYSSYGSSEKRRRPLGVALATHYLLKTASKEYQDFWTLPPLDVLQVRPKGQSDLATPVLDALEWGADLVVIVSDGCENDPPCGAAQVLRVFRQRLDSKNRTSIVHCNPVFNSDDFSVRSLCADIPTVGLRDAEDLPTMLGFAQFANGSASLFDLEDYLAHRVNRQLSINK
>NC_019678|1727397:1759812|1751163_1751415_+|WP_015117518.1|DBSCAN-SWA
MKPNWRRCISCRKVSLKSEFWRIVRVFPSGKVQLDRGMGRSAYICPNSTCLSLAQKKNKLGRALRAPVPEMLYKTLWQQLTIK
>NC_019678|1727397:1759812|1755532_1755739_+|WP_015117521.1|DBSCAN-SWA
MSSFTVKSDSGLKGDADIWNNLKQAIAISSGFQRWQMERVHADNAFETLSLDEQVQRYLRETLETLAY
>NC_019678|1727397:1759812|1727397_1728234_-|WP_015117500.1|protease|DBSCAN-SWA
MKINLFSLSVRPAPIRLGCFILSLLLPWLPYAAAVYILVKDENTRTILTMGILAIEFLFLLPWWSKYIHQQPQAFRHYGLEFTRKNGVELLRGVAIGLISVLALFVVQGMLGWLVWQPPGFSMLQLVLEGLLTGLGVAFAEELFFRGFIYDELQRDYNPAVVIPATAIIFAVLHFIKPLPVIISTSPQFLGLLLLGLACVWAKRSCRGRLGLPIGLHGGLVWGNYIIEVGKLIKYSGTVPQWVTGVNNNPLAGVMGLLSLTLLALWMRQKQLTASSEQ
>NC_019678|1727397:1759812|1739593_1740505_-|WP_015117511.1|DBSCAN-SWA
MLKKLQLKQKFTVLLLIVLILGVSVSGLALSFVLRQNAKRQVTNTALILMETMNSVRNYTSTQINPELQEKLAISFLPQSVPAYSAREVFENLRQKGDYKDFFYKEATLNPTNLRDKADDFETKIIERFQNQKKTEMSGFRSLLSGDIFYIARPLKVTQKSCLQCHSTVDVAPPSMIERYGTAHGFGWKLNEIIGAQVISVPADRVIQKANKSFVVIIGIVSLVFVAVIVLVNIFLNRQVILPLKRITRVAEEVSTGHIDVDFDQVSNDEIGNLARAFKRMKLSLEMAMNRLKSYSNPNQNRE
>NC_019678|1727397:1759812|1738335_1739541_+|WP_015117510.1|DBSCAN-SWA
MSVPPLSKPEIASGTLIDSRYIIQGMLGQGGLGRTYLAYDTRRFNEPCVVKEFAPFGTGSDGIEKCRDLFKREAKILHQLEHPQIPCFLACFEGEGRLFLVQEYVNGKTYSMLLQERREQGQTFSESEVIFWLKKLLPVLEYVHQHQVIHRDISPDNIMLPEGGNLPVLIDFGVGKQIAQLNEATQINQAGFAGNMSLVGKVGYAPREQISLGLCSPSSDIYALGVTAVVLLTGRNPSHLMDRYSLNWNWHIHTNISDTFAQILDRMLADTPKGRYQTTKEVLTQLEQLSQSPELPTLVVPDSILNSTIVPSHSQTQETVVNSIDSRENSHSPKQLNLLNPSFLENCQQHLAYYIGPMANFILEDVLAKNPQATPHQFVELLAREIPDSQTAMEFTRQIFT
>NC_019678|1727397:1759812|1749766_1751119_+|WP_157229257.1|DBSCAN-SWA
MLKLLGLKELIESISRERNLPRLAVQSAIREALLKGYERYRRAQNLDRKQFDEDYFENFEVELDIDDEGFRVVSTKTIVEEVINSDHQIALGDVQEIVDELGDDAAQLVGQEVVVDVTPDKKEFGRMAAMQTKQVLSQKLRDQQRQLIQEEFQDLEATVLQARVLRFERQSVIMAVTSGFGQPEVEAELPKREQLPNDNYRIGSTFRVYLKKVSRGQQRGPQLLVSRADAGLVVYLFANEVPEIEDEVVRIVAVAREANPPSSYVGPRTKIAVDTLDRDVDPVGACIGARGSRIQVVVNELRGEKIDVIRWSPDPATYIANALSPARVDDVRLMDPETRQTHVLVAEDQLSLAIGKEGQNVRLAARLTGWKIDIKDKAKYDFEAEDTKFAAARAQHAAELEELEELEELEAEKLAEDKLDLDNQPINSELPKTSLDENEEEFESENPIMY
>NC_019678|1727397:1759812|1758858_1759812_-|WP_015117524.1|protease|DBSCAN-SWA
MENKKQLIRCIEFVAEELDADIFLYSAEITDFNADKLINEIKATSPKRDNVVLIMTTYGGDPDAAFRIARYIKRKYKKFSLFVFGYCKSAGTLLALGADEIVISDFGELGPLDVQVTKDDDFRSESVLDIQQAMSVIGSQAFEMFESYLLNLISGTQALITTKTAADIASSMAVNLLSPIPSQIDPLRLGEMNRLMNIALAYGQRLKPEGIEVIKNLIYNYPSHSFVIDYEEAKKLFDCVREPDDLELELEEMILPLVRKPPSNEIILNLENLSEENEENSDRNHSDRERIAEESVSTDDGENEAIEGNILPFDKRQ
>NC_019678|1727397:1759812|1728919_1729273_+|WP_015117502.1|DBSCAN-SWA
MEIKANFQAGQIVFLEYKDSRLYTEVIQVVVERDLYWVRPLLLVDQQYSEAQQVTDLRSTSDLLWPINLFQPALDTQVVELYAQILIKEPKPELSQTAKQKLHQFIQELWQANQNEA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015117500.1|1727397_1728234_-|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_015117501.1|1728357_1728639_-|protease	ATP-dependent Clp protease adapter ClpS	NA	NA	NA	NA
WP_015117502.1|1728919_1729273_+	hypothetical protein	NA	NA	NA	NA
WP_015117503.1|1729438_1729696_-	hypothetical protein	NA	NA	NA	NA
WP_015117504.1|1730450_1730816_+	hypothetical protein	NA	NA	NA	NA
WP_015117505.1|1731012_1732443_+	hypothetical protein	NA	NA	NA	NA
WP_015117506.1|1732642_1733827_+	hypothetical protein	NA	NA	NA	NA
WP_015117507.1|1734002_1734194_-	hypothetical protein	NA	NA	NA	NA
WP_015117508.1|1734408_1736838_-	ATP-binding cassette domain-containing protein	A0A1M7XV31	Cedratvirus	3.1e-29	25.6
WP_015117509.1|1737175_1738090_+	PhnD/SsuA/transferrin family substrate-binding protein	NA	NA	NA	NA
WP_015117510.1|1738335_1739541_+	serine/threonine protein kinase	A0A1V0SDC3	Indivirus	6.7e-09	21.9
WP_015117511.1|1739593_1740505_-	DUF3365 domain-containing protein	NA	NA	NA	NA
WP_015117512.1|1741146_1742937_+	protein kinase	A0A2I2L395	Orpheovirus	3.9e-13	28.0
WP_015117513.1|1743126_1744014_+|protease	ClpP class periplasmic serine protease	A0A1V0SCZ1	Indivirus	9.6e-13	28.6
WP_015117032.1|1745841_1746261_+|transposase	IS200/IS605 family transposase	A0A1L2BWN1	Bacteriophage	1.9e-27	47.5
WP_015117514.1|1746333_1747110_-	peptidoglycan-binding protein	NA	NA	NA	NA
WP_015117516.1|1749078_1749543_+	ribosome maturation factor RimP	NA	NA	NA	NA
WP_157229257.1|1749766_1751119_+	transcription termination factor NusA	NA	NA	NA	NA
WP_015117518.1|1751163_1751415_+	YlxR family protein	NA	NA	NA	NA
WP_157229258.1|1751620_1751941_+	hypothetical protein	NA	NA	NA	NA
WP_015117520.1|1751882_1755026_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	2.7e-25	24.6
WP_015117521.1|1755532_1755739_+	hypothetical protein	NA	NA	NA	NA
WP_015117522.1|1755827_1757387_-	ATP-dependent DNA helicase	NA	NA	NA	NA
WP_015117523.1|1757695_1758661_+|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_015117524.1|1758858_1759812_-|protease	ClpP class periplasmic serine protease	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_019678|2134732:2149324|DBSCAN-SWA
TTTAGTTTAATGATTGACTTGTTGTTCCTAAAATTGTAGGAATTGTTTCACCTATAATAATTTCTCCAGCTTCATTTCTACGGCAAATTTCTAAAATATTAAAGGGGCTAGTAGCTGGTATATTAAAGTTTTCTTCTAATAATTTATAACTAGATAAACGCTGATTAATCTCTAAAGTAGCTTGGACAATTATTTGACCGACAATATCAATATTATTAATATTTTTGATGTTAACTGATAATTTATCTATACTTTGGATAATTCTTTGATTATAAATGGTACGTTTAATTGTAATTTGATTATTTTCAATAGTAGCTTCTTGTGTAAATAAATGAACTTCAGACATATCATCTTTAAATCGAACTATGATTTTGTTGAGTAAATCTTGAGTAACTGCTTGCGGTTGATTTACCTTCACAATCGCTTCTAGCTCAATTTTGTCAATAATTGCAGTTAAATCGGAATGCAATTCTTGCTGAGGAGGTACTGCAAATGTTTGAAATTGATAAGGTTGAGTCCAGATATATTCGGTAATCCTCATTCCCGATTCTTGTAAATTACCTTGGAGTTGAATAATTGTATTTCCTTCAATAACTTCTTTGGCACCATTTAAACGACATATTTTCAATACAGTTGATAAGTTTATTGGTTGTTCTAGTACTGTATTACTAAATTCTATTTGATTAATATAAAAATAAAATTTGATTGCTAAATCACCGATGAAAGTTTTATCTGTTCTATTAGATAACTTAACATTTAAGTCTGACAAATTTTCAATGATATGCTGAGAATTTAATTTATATTTAACAGAAAAAGATTGATTATCGATAATTTTTTCAGATGAATCTGGGATAATTTCTTGTAAATTACCTTGGAGTTGAATAATTAACTGGTTTGCTAATTGACTAACTGGGATAACATTATTTTCTGGGAAATTAATTTTAACTTCTATAAAAAATATTTGATTTTGAAGTGATTCAAACAATTTAAAAGGAAATATTACCTGCGATGGCTTAGTTAGCTGCATCGTAGGCACAAGAATTTTTAGGGAGTAAAATGTCTGTGCTGGCTTTGCTATATCAATAATTGATTTTGCAATTTTAGCTTGTCGCCAATATTTTTCAGGGTCGCGGTCATTTAATGTTAATTGTACTTGAAAATAATAGGGAAAGTTTTTAAATTGGTCGAATACCTCAACTTTTTCTCCAAATCCCGAACTTTTTAAATAAATACTCAATATTTTAATTAACCCTGCTTTTGTTCCTCGCAAACGATAGAGTCCGACAATTTGTTGAATAAATTCTCTTTTTACTTCTACTTTCCAATCATTCCTTAAGCTTAAAGCTACCCAATTTGCTAACCAAGGTAAAAAGTCTTCTGGTGTTTGCTGGGGATTAAAATAAAGATGAATATTGTCAATAATTTCTTCCAGCCCAGGTGGATTTTGAGTTTCTTTGGTAATTATTTGCTCTTGGCTAGAAGTTTTACTTGTTCCACTAAGTATTTTTTCAAATGCAAGCAAAAATTGACCAAGGAAATCATCTTCTTGGAGAACTGTAGGTAAATATTGTTGATAGCTACTAACTAATTTAGATTGGTTTTTGGTCATTATCAAATTCTACCAATATTGTAAACTGGCTATTTTTTATATCTAGGCTAACTAACTGGTTATATGCTAAATCAATATCTGATTCTGAATTATTAACTAGTAAATTTTCAACATAATCTACACCTTCTAAATCATCCAATATTTTATATAATTCGGATAGATAAATACCTCTAGCAAATGGCCATCCTTTACCACCCCAATATTTTCCAGAGTGCAAGGGATGAAAGAACCAATTAACTTCATTTTTGGCATTTTCTTTAATTTCTTCTGCTTTTGTGCCATCTTGAACTACTATTTCCGCTGTTACGGCTACCGATACATATAAAGGTTCTACAATATGTAAACGAGTAGTTAAAAGTTTTCGTTCGTTCAGAAAATCAAGTAATTCTTTATATTTGTTATTATTATTGTTCTCTTGACTATTCTGTTCCGGAACAACGATTAAACTAATATTACCTTTAGCAACTGTTTCAGTATTAGATTCAGATAAATTACGTTGTGCTAAACATTTAACTCGCGCAATTTTTAAAGTCGAATCTGACGATGTATTCCAGTCTTCAATAATTAGTTGTTCGTAGTCTATCGTCGTAACAGCCCGATAACGTTGACGTAATTCTAATAAGGTTTTATTAATCTCCGACTGTAAACTTTGTTGTCTCTCTTTAGCAGGAATATTAGGTAAATTCCATTGTTCTCCTTTAAGTAAACTGATAAAACTGGCATAATTTTCATCACCAATTTGATTAACCCGGTAAAGAGTCATTTCGCTTAACCAAGCTAATAATTCAATCAGAATAATTCCCGTATCTGATGGGTTATAATCAGTCCATTCAGAATATTCAACCGAAATTTGAGAAATTGCTGATTCTACTAAGTCAGCATAGGTACGGTCATCGAGATTTGGTAATGGTAAGGGCATAAGTTAAGATGGGAATAGGGCATTGGGAATTGTAAATTTATTTATGACTTTAAATTAATAGTATGATTGCCAGAATATATTAAAGTGTCGGCATTTAGAGATGAGACATTATCTGTTAATGATGATATTTCTAATGAATCAACATAATTAACTCCAGGAATAGATTGAATTATGGCGTAAAAATCAGATTTACGGGGATAGCGTCCAAATTGCCATCCTTCCCCTTTACCTCCAGTCAATGGATGAAGAAAAGCTTCTAAGCGTTGTTTGATATTGTTTAACAGCATATCTGCACCTTCGAGAGATACAGGACTTATAGTTGCATTAACGATGACTTCTTGCCATTGGGGAGCAGTGACTATTAAATCTACCGTAGGTTCACACCGGGAAAGAATATAGATTTCGACTTGCTTGAGTAAAGCTAAACTGGGAATTGGTTGATTTTTGCTACTATAGGGCAGAATAATTAATTTAACTTGTCCTGCTCGATTGTTAATTTCCTCCACTAACTTTTCAAATTCGCTATATTTGGGAATTGATTTTTTTTCGTCAAGAAAATCTTGAAAAGAAATATCTGGGTTGCTGGGATCTAACCAAAGGTTTTCATTGAAGGAACTAAAGTTTGCCGTTGCCAAATCTGGTGTAACAACTTTTACTCTGGCAACATTAGTAGAAGCTTCATAAGCTAAATCTTCGATGTCTTCAAGGGTAACAGCGCGATCGCGATGACGGAGTTGTTTTGGTACGCGTTTTTTCAGTATTTCCAAGGTTTCTTGTTCCGCACCTCCTGCTGATGGTTCGAGGTTAATGACTCGATCAATATAGGGAATAGTAGTTTTGAGTTGAGTAATGGTTTCTGAAGAGATGTTTCCTTGTTTACCTCCTCCAGTACGGTAAAAATTTAATCGAATATTATTCTGTCCTCTGGGAGGAATCATCCCTGCTCTCCCATCACCAAAACGAATTTCTCCGGTTTGTCGGTCTAAAGTATAATGACGATGATTGGCACCAGAACCGTAAAAATCTGGTACTTCTTGCCAAATTACCCAAATTTCTTCTATTTCCCCGACATCATCTTGAATTACTTTAACTCTATCTGCTTCTAGTTCAACAGGAATTTGTTGTTCTTGAACATCTAGCTGTTGTCCTAATAAAATCGGACTGTTATTGGCAATAAAAACTTGATTTGCTTCGGAGTTACTTGAACCTAAAATCTCTTCTTGAAGACTGATTGCTTGAAATGCCCACGTGGTATTTGTTAATATACGACGCAGACGAGGTTTAACCCGAAAATCACCATCTTTCCAACGAACTCGCAACCAATATAATTGTTTATCAAAGATTTGTATTTGGCTGAAATCTACGGGTGGAATAAATTGAATTAAACCCGATTGAGAAAATGCTTGGGTTTCATCTTGTACTCCTAATAGTTGCCAACCGTGATTACTTGAATATTCCCAAACTAATTCGGGTTTCACGGTTTCCGATGGAATATCAGCCGATAATTCTTCTGGTGATGGTGGTTCAACTTGAGCGTAAAGGGTGACTGTTTTATTGTCAAAAGATTTATCAAATCCGAGATAAAGTGTTGGTTGTTTATCTAAAGTGGGTGTAAAAGGTTGAAAGTTACCATTTCCCTCAGAATATTCATAATTGTTATTAGAAAGATAAATAGATTTTTCCTGTAGTTCAAATTTGTAACTTAATTTTAATGATTTAATCAGAGGGGGGTCGTAAGTTGGAGGAATTGTTTCTGTAATAGTGTCTCTACGGAAAATTTTGGTTCCCTTTTTTCTCGCTTCAGGATTTATATTTGATGATACTGTGAAGGTACTTCCTTGAATTGTTTCAATTTGGTATTCTTCTCGTTTCTCTGTATTATTTTCTATCCATACCATCCGCACAATATCATTTGTACTGAGAAAATCGCTAGCATTTCCGATAATGTTTATTTCTTGATTACTAGGACTATTATTTACTATGGCAACTTCATTATAAATAGCATACTTTCTTGTTTTGCTTGGGCTACCAAAATTACCTTGATTAATTCTAGCTCTCAGCCAATAACGAGTTTCTCCATTTACAGTACCCGGAGATGGGATATTTTCTAAGTTGGGAAATTCTAATTCTGTTTGAATATTATTTGACTCTTTAATTTTTCGCCATTCTTGACCGTTACTAATTTCCCATATTATTTGTAAATTATCTGTTACTACTGGTTGATGATTTAACTCCAAATTAATGATGATATTCATATTTGGCTTAATAAAATCATCGTCTAAAGCTATATAAAATGTATCATTTAATTCTGGCTGTTCGCCAAAAGGATAAAAATCTTTTGTCAAGTCCAAAGGGCTATTATTAAATAAACAAATATCAGGTATTAATTCGGTTTCGTCAATTTCTATTTTGCCTTGAATATTGGTAACTAGAGGTAAATTATTAGCTATAGCAGCATCAGTAATATTAGTTAAACTTGCTCTCAGCCATTTTGCTTGTTGTCCGTTTATTTCTAAAGCTGTGGAAATCGGTAAATCTGAAAATGTAAATTGATTATTGCTATCAAAATCAGGAGTTTCAATTTCTTCCCATTTATAACCATTCCAGTAAAACCAATTAAGTTGTGAATTAGAAAATTGACTGACGTTATCCCCAGAAAAAATCAGTTTAAAATCAATTAATTCCGGTAAACTAAAGATTTCCGGACAATTTATATAAAGAGAATGTTTGATAGCTTGATTCCCTTCAAAAGCGAGGAAAGCAGCATCTTTCTGTCCTATTGCTTCTAAAGTGCGGTTACTATAGTTATCTTTGTTAGGTTCTATTACAAATACCGCTTGCAATTGTGCTGTTGTTACTATCAATTCCCTATCGGTTTCAAAGACAATTTCTTCGTCCGAACCCTCTACTGGTGGTGCAGAAACTTGGGTACGAGCGGGAACTAAAGCATCTAGGGGACTTCCTTCTGCTAAATAGAAGTTTAAAGGTACTTTGGCTGCTTGGGGTGGTTTGAGTTGTCCCCCGATTAAATCGAGGAAAGCTAAGAAATTTTTTTCAGGTACTTGATTGAGACGATTACCAATTAACTTTACCATCCGAGCAAAGATGCGAATTAATGCATCTCCTGCATCAACTTTTTCTATAGCAGGTTTCCAATGGGTAAATTGTTGGGCTAATTTTTCAGTTTGCTCAACAATTTCCTCATAGGTACGCTGGTCAATTTTTGGAGGTAAAGAAGTCATAATTAATTACCTTAATCAAATACTTTAATAAACTAAGTAAAACGAGTAATGAGTAATGAGTAATGAGTAACAACTAATATCATTTCTTTATAAAGATGCGCCGAATTCAGCCTACGCAGGTAGGCTTTGTATCAGTAGCTCCACTCTTTCAGAGTGAGAGCGATTGAGCGCAGCCTCATACAGAATTGGTATAACAAATTACTGTAAATAAAAAGGATAAACTAAATTAAAAATATTATTTGTTGTGCGAATTTGATAATTAACTTGAATTAAAATTAAATTTGGTTGACTTGAATCGGGAATTGTATCTACATCTAAAACATCAATTCGAGGTTCCCATTCAATTAAAGCGTCTCGGACATCACTAACAATTTGTCCCACCGTTCCTAAGCTATTGGGAGCAAAAACTTTCTCGTGAATATTACAGCCAAAATTGGGACGCATGACTCGTTCTCCTTTGGATGTACTCAAAATCATCCAAATCGATTGACGGACGCAATCTTCATATTTTGCTACCTTTATTTGACCGTTTTCATCAAGTTCAACCGGTGAAGTCCATCCCACCCCTAAAAAATCAACATCCACTACATCACCTCCAAGGAACCATCATTAACTTTCACCCCAGCAGAACATTTAATTCCTAAACCAGATTTTGCTGTAATATTACAATTGTTACCGGCTTCTAATTGATAATTTTCTTTAGTTTTTATTGATAAATTGTTACATTCAATCGCAACATCATCATCGCTACTTTTTAAAGTAATTTTTCCTTTTGTTTCAATAGTTAAATCTTTTTCAACTGTAATATTCATTTTATTATCTTTGGAATCAATCAAAATTTGATTATTACCAGTTTTATCTTGAATCACAATTTTTTCTTCTCCATCAGTATCATCTAAAATAATCTGATGACCGCTACGAGATTTAATCACTCGTTGATTATTTTTACCATCATCATTTTTTACAGGTGGTTTATCTTTACCGTTCCACAAAGCTCCCAAAATATAAGGAACATTCATATTACCTTGTTCAAAAGCAACTAAAACCTCATCGTCAATTTCTGGTAAAAAGTAAATCCCCCGGTCATTTCCTGCCATTGGGGTTAAAACTCTAGCCCAATAGCTTTCTTCTGTTTGAGAAAGCCAAGGGAATTTTACTTTCACCCTTCCTAATCCATCTGGGTCTTTATTATTAGTAACTATGCCAATTGTGACACCTGGGAAATGATTATTTTGTTTATTATCAAGTAATAAATCGTATCCGTTCATATCGCATTCCTCTTGACAGTAAACGAAGTTTGATAACCTTGATTTCTCGAATAAATATGTTTTGCACTGGTGATATAATAAATACCGCTAAATCTTGTCCCGACTCCAGCAATTTCAATTACCTTCCCAGCACGTAAATCGGGATTACCTTGACAACTTCCTTCACCAGTAATGTAAGAAAGCAGCCCATTTTGAAACTGTCCTAATGCCATGCCATCAGCTTCAGCTTTACTCGATACAGCTTGATTAACTATCGTATAACTCGATTCTCCAAAGGCTTTTTTAACGGTTTTTGCACCAGAAGTTGAACCTCCCATTAATCCAGCTTCTTTTCCTACACTAGCATTTCCTACTATCTCTTTCTTTTCTTGAGGAATCCAACCTCTGACTTCAAATTTATGTACTTGGCTCAGAGTACTTAAACGAGGTAAAAATTCTTGTAAACCTTCTCCATAAGTCAAAGTTGAAATTTTAGATTTACTATTATTATGAGGACGAAAAAAAAGAGTTTTATTGTCTACCATCACTTCGTAACCAATACGTCCCGCTCGCTCTTGTAAAAATTCCCAATCTGTTTGATTGTGCTGTAAAATATATTCTAATTTAACTTTACTATCAGTAACTTTTGGTGTCAGTCCTCTGCTTCTAGCAATTTGACTAACAACATCACTATCTTTCATTTGTAAAAATGATTTTGTATGATGACCTCTCAACAAACGATGACGTAAATCGTGACCTCTTACTACTAATATTGGATTTGCATCTTGGGTATATTCTGGTTCTAATCCTGTAATTTCTCCCACCATTACAGTTTTAATTTCTTGCTCGTATCCCATTTGAATTTCGACTTCATTGCCAATATCAAATGTTTTGTCATCAACCCAGGTCATTTCTTGTTTTACCAAATCCCAAGTAACTAATTGCAATTCAAACATACTCGGAGCTTCTAAATCCTCGGATACCGTAACCGAAACTAGATCGGCTTTTATTCCCGAACTAAGGGATTTACCTTGAATCAAAATTTGTAAATTAGGGTTTAATAAAGAAGCATCATTTGGCATGATTTAATTCCTCTAAGTTAAACTATTAATTCGTAAAGGAGGAATTGTTAAAACCATTCCGGGATTTAATTTTCGGGGATTAATGAGACGATTTTCTTCAGCGATTATACGCCATAAAGAAGGGTCGTTATATTCTTCAGTGGCAATACTACTTAAAGTTTCTCCTCGTTTGACAATTCTTACAGGATCATCAATTGGATTCTCAATTTTCGCATTTTTTTGCGGTTCTCTCCACTCTTTAAATGTACAGTTTAAAGTTGCTCTCACGGGTGTAGCATCTTCTAGAAAATGGGTAAGTCTTTTAGTGACACTTTCTAAAAAACCATCGGGTAATAACACGCTATCTTTACCGGAAATAGTCCCCCAAATTAACTGACAGCGAGGAGGACGTTTAGAATTTTTTCCAATCCGGGGTTGAGTCAAACTAAAAATTTTGCGGGTATAGTTTTGGACGTTTTCAGGTGGAATTCCTGTAAGTGTGGTGTCAAAAAATAATTCCAGGCTGAGTCTAGTTAATTCTTTGGAAGTTACCGGATTGTTTTTGTCCATTATCCACCCAGTTTTGCTTATTTCCACTTGGTTTGGGTTAAATAAAACTTTGAATTCATCCGCAAAATCTCCGGGATTATTTTTTTCAGCTTTGATAGTTAATTTTTCTAATGTCATCGAGTTTTCCCTCTACGTTCGCTTTCAATTACTAAACGTCGCATTAGTTTGCGCTCAACTTGATTAACTATGGTATCTACATCTATCTTTTTTAAATTGTTGGAATTTGATTGATTAGCCAAGGGAGAAACAATAGTTTCTGCTGGTGGTGAAGGTAATGGTAATACTTTAGGAAGTGAAGAAGAATTATTATTCGATAAGTTGGGTTGAGAATTATTAGTTATTTGCGATGAGGAATAATTTTTTGTTAAAGGTAAAGATTGATTTCTTTCAGGGGTATTAATAGATGGAGTAATAGTGACTACGGGAAGATGATGATTCTTTTGAGAATTTGAATAATTTCTATTTAATGATGTTTCTTTTTTTATTGAATTATTTTTATCAGTTGAAGGTTGAGTAGTTACTATGGGTAGATTTGTTAAATTAATTTCAGTCCCTAAGTTTTCTTGTTTGCTATAAATAATATTTTCGGAATTATTTTCTAGTTGAGTTTGTTTGGAATTAGTGAAAGTATTTAAAGGATTAGTAACTGGGAGTTGGGATGAGAATAAATCTGAATTTTGTTGTTTGATTTGAACAATAGGAAGTTGTTGAGAAGCACTTATAAAACTTTGTAATAATGGCATCTCTCCGGTTTCTGTTATTTGTTCGGATATTGCTTGGGATGAAACAACCGGAATTTGTGGAGAAGATATAGAAGTTTGATTAATTTGATTATTGTGATTTTCTAAACCAAGAGCAGGGGTAATATTTTCTGAGTTTTTGATGTTATCAACTGATTTAATTGTCGAAGATTGAGAATTATCTGACTTTCGTTGAATTAAAGGTACAGAATTATTCTCTTTTTTGGTATTCGATTGTAACGGCATTTCTTCGCTTTCTGTTAGTTGTTCAGATATTGCTTGGGATGAAACAACCGGAATTTGTGAAGAAGAGATAGAAGTTTGGTTAATTTGATTTTCTAAATTAAGAGAAGGGGTAATATTATCAATTGGCTTTTCTTTTCGTTGAATTACAGGAGATGTTGATGTAAATTTATTTTCTCCGCTTTCTATTCCCGATTGATTGGTTGCTGAAACAGGTTGTGCATAAACAATAGGAACATCGTTAGATACACCAGTATTAACATTACCCCAACGTTGTATTTGTTGACCTAGAAGAGGTAAACGATTTAAAAGGCGATCGCAACGATTTATGATACGCTGACTCATAGATATTTTCATCATCCCCGGTTGATTTAAGGGACGATTCAGCCGATTGAGTAAACCAGTATTTAAGGAATCTTGCCAATTTGAGGAAACATCTGTCATTTTTTTATCGCTTCATTTTATCAATTATTTTTCTAAACCAATTTCATCTTGATTTTTTTCAGGGATATTAAAAGCAATGTTATGTAAAAATCAAAATCTACCAAATTTAGAAATTCCTTGATGAACCAGTTCAATTTTTTCCACAGCAATTTCATCATTACTAGCATTCAATTGTGGACCGTCCCATTTAACTGGATATGCATTTTTAAAACTCCACCACATCACGGGAATTTGCTGATTATTTAGTAAAATAACCGTACCATTTAACTGTTGAATTAATCCTTGATTTGTTGCTTCGTACCAAAGATAAAATAAATCAATATTAATTAATCCTCTATTTAAAACCAAATTCGGATAAGTCGTATGTTTGGGAAATTTATGTACAAAGCCATTTAATCCCCCCTCTTGATAACTTTCCAACTCAATTTCGCTACTTAAACCGCTAACTTCACTAAAACCACCAATAACAACCCCACCAATTTCAACCAAAAAGTTATAACCCATAAAGGGATCGTGTCCCAGAAAACTCGCTGTAGAACCAGCCGCTAAAACTGCATTCAGTCCGATAAGTTTAGGATTCATACCACCTCCGGTTAAATTTAGGAATTGTTGTTTTGCTCGTTTAGTCGCTGATTAATCTGCGCTACTTGAGCAACCCACTGCTGACGCTCTTGATGTTCCATTATCATTATCTGTTCGTAAGACCAATGAAAATGATAAGCAAGATAAGCTACCTCCTCCCTGAGTCTTTCTGGTGGGTAGCAAACTACTCCCCCACCGGAATAGTTTCTACCTCAAATTCACCTTCACAATGGGGACAAGCTACCCGCAGACGGCTATGACCATTTTGGTTAATTCTTTGATAAAAATCCTGCAAATAAACCAAATCTCCTGAAAATAAACCCTCAATTATTTTGGTATTAATTTGGTCTAAAGTTCCCAATTTAGTAATCACTCTTGCTAACAGAATAATCACTAAATAACCAGGATTTCTCTGCACTCTTGGGTCTTTAAGTGGGGTAATTTCATCATAAGCAGTAGAAAGTCTCATAATACCTTCTTGATGACTGTTACCTTCCGAATCAAGATACCCTTGAGGCAATATAAAAGGAAATTCAGTTTGCTGCATGATTTTACTTCAAAAAAACTAATCAAAAAAATACTAACCAACAGTAATACCTTCGTGAACTAATTCCAAAGTTTCTATGGCAATTTCATCAGAAGTACCATTCAAATCCGGAGCATTCCAAGTAGTTGGCCAACAATTTTCTAAATTCCAGCGAAGCTTTTCTTCTCCCCTATCATCAGCCAAAATAATTGAAAGATTACGTCTATCTGTATCCCCACTTTGTAATTTTTTGTGCCATTCCCAAAGTTCTTGATTATCAGTAATTCCCCGTTTTAAGGTGATATTTCCGAAAGAATTTAATGCAGGAATTTGACGCTGATTTAATGCTCTATCGGTACCTTCTCTATAGGTTGTTGCATTGCGAGTAGCTGTTAAGCCGCTGCATTCACGAAAACCAGCATGAACGATACCATCCCATTCAACCCAAAAATTATAACCAAAGTAGGGGTCATGGGGGTTAGAAATTGTCGGCATAATCAGATTATCTCCTTAAATTGGTAATAGGTAATAGGTAATTGGTAATAGGTAATTGGTAATTGGTAATGGGTAATTGGTAATTGGTAATTGGTAATTGGTAATAATAAATTATTGACTTTTGACTTTTGAAGCCCCTTGTTTAAATCCCCATAGATATTCCAGCCTTCTTCTTTCTTCCTTCATTTAATGCTAATTCCGCTACTACTTTGAACTAGTAAAAGTTGAATAAATTCCCCCGGAACTGTAGGAGCTAAACCAACTTCTGCTACTACCTGTCCCATTTCTCTATTTTCAGGAGGGTTAGTTTCTTCGTCGCATTTAACATAAAATGCCTCTTGCCCAAGAGTACCTTTAAGCGCACCTTGTAGCCATAAAGATTCACAATAAACGCTTAATTCTCTTTCTAATCGTATCCACAAAGAGAAAGTATTTGCTTCAAAAACTGTATCTGCTAAATTAAAATTTGCCCAGCGTCCAAAAGTTATAAATAAGCGACGCACGTTGACATATTGCCATTCAGGTAAAGGACTTAAAGTACGTACCCCCCAAACCCGCATTCCCCTTCCCCGAAAGCTACGAATACAATTGATTCCCGGTTGATTTTTAGGGTTCAATTGTTCTTGCTCTGTGGGAGTTAAGGAAATACTCAGATTTATTACATCTTCAAGCTCTATATTGGCAGGTGCATGATGTACTCCTCCCGTAGTATCAGAATTTGCATAGATTCCAGCAACATGACCGCAAGGAGGAATAAAATCTGGACGATTTTCGACTTTTAGCCAAGGGGCATATAATGCACCATAGTGACTCGAAAATTCCTTTCTTTGCCAATCTAATTTTTCCACATCATTGACATTCAAAGCATCAAGAATTGCAAAGCGATTTCCCACATATTCACAATGTTCTAAAACTGCTTGCTGCATTTTGATAATTTCATCAGCATTGCTTGCAAGCATGATATCGGGAACGCAAATTAAATCAGTATTTTCTAGTAATTCGCTTGCTTCTAAAGCTTGTTTCAAAGTATCAAGACTATTATTTTCTAAAGCTACGACATAACAAAGACGACCTCCATTTTCAAAAAAACCTTTGATGGCATTTTTTAAATATCCCTGACTCTGACTTCCCTTGATCTGACTAAAATACTGGTCAAACTGAGTTCTTAAAGTTAGCTTTTTTGGTTCATTATTATCTGAAGAAGCCAAACCAAAAAAAACTGGAACTCCCGTCAACAATTCAGATTCCGGTGTCGGAACAATATGATTGAGAGAAACACCTGGGATTTTTGGCTTTAAATTCTGCATCAAATTCACCACGAAGATTATTTAATAGAGGGAGGGAGGGAGTGAGGGAGTGAGGGAGAGAGGGAGACAAGGGGACAAGGAGAAATAATTATTAACTTGCTACTTGCTACTTGCTACTTGCTACTTGCTACTTGCTACTTACTACTTGCTACTTCCAAAACTCTACTGTCCCGAACCATCCCACTGACTGATACGGAAAATTACGAATTCTGCGGGTTTAACTACTGCTACACCAATTTCAGTAACCACTTGACCCAAATCCCGGACTTCTGGAGGGTTGGTTTCTGCATCGCATTTTACGTAAAAAGCTTCTTCTGGTGTTGTACCAAATAATGCTCCTTGTCGCCATTCGTTTACTAAAAATGCACTGATATTGCGGCGAATGTTTGCCCAAAGTTCTGGGGTATTCGGTTCAAAAACCACCCACTGAGTTCCTTTATCAATGGAATCTCTCAAGTAGTTAAAATGACGGCGAATATTTACATACTTAAATTCTGTATTTGCATCACCACCCAAAGTCCTCGCACCCCAAACCCGAATATTACCGTTTAATTTACGAATGCAGTTGATTCCGTCAGGGTTGAGTCCATCCTGTTTGGATTTGCTGAGATTATATTTTAAATCTAAGGCTCCCAAAATAGTTTCATTCCCAGGAGCTTTATGTACTCCCCTTTGTCCATCAACCCTTGCATAAATTCCTGCAATATGACCGCTGGGAGGAACATAAATATTACTATTGCTACCAGGGTCAAACACTTGAATCCAAGGAAAATACAAAGCTGCATATTCTGAGTTGAAAGGTTTGAGAGTGTCAACAACTCCCGTACTGCCCAGATCGATAGTTTCATCACTATCTAAAACAGCAATGCGATCGCCCATTTTTTCGCAATGGTCTTTGATATCATCTCTTAAGCTCAAATTTCCTGGAGCAGCGACGATGGTAATCTCATCAATAGCTTCAAATTTATCCAAAACCTCGCTAACTTCGCTTTCCCCAGTTATCCAGGTGATATAGCAGCGAGTTCCTCCATTCCTGAAAAACCCGTAAACCGCATGAGCTAAAGTATTTTGACCTTTAGTATCATCAGTTGGAAGCAGAAAATCACCAAAGAATTTCTTAAATTCAGTAAAATTCGTACAAAGTTTAATTTCCCCTTCTTGAGCAATATTTGGATCTATTGGATTTGGTTGTACGGGTATTTCAACTTGATAATATCCGGTGATTTCTGCCCCTGAAGCTACAGGTTCGCTAAACTTTATTGTTGTAGATTTATCTGTATCATTATTGGTAATTGGATTTTCATCATCTAATTCGACAGAATTTCCACCAACAAAAAAACCGTAAGTTCCCTCATTCAGAACTACTGGATAATCTCCTGGAGGTAGCGGATAATTTTTTCGATTTCCACCTTCACCTTCCCCAATTTCAACGGGAGTTCTTGCGCTACCGACAGACCTTGTTGATGTAGTCGCAGCGTTATTTGACGACCAAGCATTAGCATTAATCGTACCAATAAAAGCCGCAATACTAGTACCAACCCCTACAATTGGAGCAGAACCAGAAGCAATTTCTTCTACATAAACACCGGGAGAAAGATAAGTTGGCAT

Protein sequences of DBSCAN-SWA_2

>NC_019678|2134732:2149324|2141765_2142830_-|WP_015117821.1|DBSCAN-SWA
MPNDASLLNPNLQILIQGKSLSSGIKADLVSVTVSEDLEAPSMFELQLVTWDLVKQEMTWVDDKTFDIGNEVEIQMGYEQEIKTVMVGEITGLEPEYTQDANPILVVRGHDLRHRLLRGHHTKSFLQMKDSDVVSQIARSRGLTPKVTDSKVKLEYILQHNQTDWEFLQERAGRIGYEVMVDNKTLFFRPHNNSKSKISTLTYGEGLQEFLPRLSTLSQVHKFEVRGWIPQEKKEIVGNASVGKEAGLMGGSTSGAKTVKKAFGESSYTIVNQAVSSKAEADGMALGQFQNGLLSYITGEGSCQGNPDLRAGKVIEIAGVGTRFSGIYYITSAKHIYSRNQGYQTSFTVKRNAI
>NC_019678|2134732:2149324|2141085_2141769_-|WP_015117820.1|DBSCAN-SWA
MNGYDLLLDNKQNNHFPGVTIGIVTNNKDPDGLGRVKVKFPWLSQTEESYWARVLTPMAGNDRGIYFLPEIDDEVLVAFEQGNMNVPYILGALWNGKDKPPVKNDDGKNNQRVIKSRSGHQIILDDTDGEEKIVIQDKTGNNQILIDSKDNKMNITVEKDLTIETKGKITLKSSDDDVAIECNNLSIKTKENYQLEAGNNCNITAKSGLGIKCSAGVKVNDGSLEVM
>NC_019678|2134732:2149324|2142842_2143496_-|WP_015117822.1|DBSCAN-SWA
MTLEKLTIKAEKNNPGDFADEFKVLFNPNQVEISKTGWIMDKNNPVTSKELTRLSLELFFDTTLTGIPPENVQNYTRKIFSLTQPRIGKNSKRPPRCQLIWGTISGKDSVLLPDGFLESVTKRLTHFLEDATPVRATLNCTFKEWREPQKNAKIENPIDDPVRIVKRGETLSSIATEEYNDPSLWRIIAEENRLINPRKLNPGMVLTIPPLRINSLT
>NC_019678|2134732:2149324|2144896_2145388_-|WP_015117824.1|tail|DBSCAN-SWA
MNPKLIGLNAVLAAGSTASFLGHDPFMGYNFLVEIGGVVIGGFSEVSGLSSEIELESYQEGGLNGFVHKFPKHTTYPNLVLNRGLINIDLFYLWYEATNQGLIQQLNGTVILLNNQQIPVMWWSFKNAYPVKWDGPQLNASNDEIAVEKIELVHQGISKFGRF
>NC_019678|2134732:2149324|2146591_2147716_-|WP_015117827.1|tail|DBSCAN-SWA
MQNLKPKIPGVSLNHIVPTPESELLTGVPVFFGLASSDNNEPKKLTLRTQFDQYFSQIKGSQSQGYLKNAIKGFFENGGRLCYVVALENNSLDTLKQALEASELLENTDLICVPDIMLASNADEIIKMQQAVLEHCEYVGNRFAILDALNVNDVEKLDWQRKEFSSHYGALYAPWLKVENRPDFIPPCGHVAGIYANSDTTGGVHHAPANIELEDVINLSISLTPTEQEQLNPKNQPGINCIRSFRGRGMRVWGVRTLSPLPEWQYVNVRRLFITFGRWANFNLADTVFEANTFSLWIRLERELSVYCESLWLQGALKGTLGQEAFYVKCDEETNPPENREMGQVVAEVGLAPTVPGEFIQLLLVQSSSGISIK
>NC_019678|2134732:2149324|2137300_2140501_-|WP_015117818.1|plate|DBSCAN-SWA
MTSLPPKIDQRTYEEIVEQTEKLAQQFTHWKPAIEKVDAGDALIRIFARMVKLIGNRLNQVPEKNFLAFLDLIGGQLKPPQAAKVPLNFYLAEGSPLDALVPARTQVSAPPVEGSDEEIVFETDRELIVTTAQLQAVFVIEPNKDNYSNRTLEAIGQKDAAFLAFEGNQAIKHSLYINCPEIFSLPELIDFKLIFSGDNVSQFSNSQLNWFYWNGYKWEEIETPDFDSNNQFTFSDLPISTALEINGQQAKWLRASLTNITDAAIANNLPLVTNIQGKIEIDETELIPDICLFNNSPLDLTKDFYPFGEQPELNDTFYIALDDDFIKPNMNIIINLELNHQPVVTDNLQIIWEISNGQEWRKIKESNNIQTELEFPNLENIPSPGTVNGETRYWLRARINQGNFGSPSKTRKYAIYNEVAIVNNSPSNQEINIIGNASDFLSTNDIVRMVWIENNTEKREEYQIETIQGSTFTVSSNINPEARKKGTKIFRRDTITETIPPTYDPPLIKSLKLSYKFELQEKSIYLSNNNYEYSEGNGNFQPFTPTLDKQPTLYLGFDKSFDNKTVTLYAQVEPPSPEELSADIPSETVKPELVWEYSSNHGWQLLGVQDETQAFSQSGLIQFIPPVDFSQIQIFDKQLYWLRVRWKDGDFRVKPRLRRILTNTTWAFQAISLQEEILGSSNSEANQVFIANNSPILLGQQLDVQEQQIPVELEADRVKVIQDDVGEIEEIWVIWQEVPDFYGSGANHRHYTLDRQTGEIRFGDGRAGMIPPRGQNNIRLNFYRTGGGKQGNISSETITQLKTTIPYIDRVINLEPSAGGAEQETLEILKKRVPKQLRHRDRAVTLEDIEDLAYEASTNVARVKVVTPDLATANFSSFNENLWLDPSNPDISFQDFLDEKKSIPKYSEFEKLVEEINNRAGQVKLIILPYSSKNQPIPSLALLKQVEIYILSRCEPTVDLIVTAPQWQEVIVNATISPVSLEGADMLLNNIKQRLEAFLHPLTGGKGEGWQFGRYPRKSDFYAIIQSIPGVNYVDSLEISSLTDNVSSLNADTLIYSGNHTINLKS
>NC_019678|2134732:2149324|2136320_2137259_-|WP_015117817.1|DBSCAN-SWA
MPLPLPNLDDRTYADLVESAISQISVEYSEWTDYNPSDTGIILIELLAWLSEMTLYRVNQIGDENYASFISLLKGEQWNLPNIPAKERQQSLQSEINKTLLELRQRYRAVTTIDYEQLIIEDWNTSSDSTLKIARVKCLAQRNLSESNTETVAKGNISLIVVPEQNSQENNNNNKYKELLDFLNERKLLTTRLHIVEPLYVSVAVTAEIVVQDGTKAEEIKENAKNEVNWFFHPLHSGKYWGGKGWPFARGIYLSELYKILDDLEGVDYVENLLVNNSESDIDLAYNQLVSLDIKNSQFTILVEFDNDQKPI
>NC_019678|2134732:2149324|2134732_2136340_-|WP_015117816.1|tail|DBSCAN-SWA
MTKNQSKLVSSYQQYLPTVLQEDDFLGQFLLAFEKILSGTSKTSSQEQIITKETQNPPGLEEIIDNIHLYFNPQQTPEDFLPWLANWVALSLRNDWKVEVKREFIQQIVGLYRLRGTKAGLIKILSIYLKSSGFGEKVEVFDQFKNFPYYFQVQLTLNDRDPEKYWRQAKIAKSIIDIAKPAQTFYSLKILVPTMQLTKPSQVIFPFKLFESLQNQIFFIEVKINFPENNVIPVSQLANQLIIQLQGNLQEIIPDSSEKIIDNQSFSVKYKLNSQHIIENLSDLNVKLSNRTDKTFIGDLAIKFYFYINQIEFSNTVLEQPINLSTVLKICRLNGAKEVIEGNTIIQLQGNLQESGMRITEYIWTQPYQFQTFAVPPQQELHSDLTAIIDKIELEAIVKVNQPQAVTQDLLNKIIVRFKDDMSEVHLFTQEATIENNQITIKRTIYNQRIIQSIDKLSVNIKNINNIDIVGQIIVQATLEINQRLSSYKLLEENFNIPATSPFNILEICRRNEAGEIIIGETIPTILGTTSQSLN
>NC_019678|2134732:2149324|2147878_2149324_-|WP_015117828.1|tail|DBSCAN-SWA
MPTYLSPGVYVEEIASGSAPIVGVGTSIAAFIGTINANAWSSNNAATTSTRSVGSARTPVEIGEGEGGNRKNYPLPPGDYPVVLNEGTYGFFVGGNSVELDDENPITNNDTDKSTTIKFSEPVASGAEITGYYQVEIPVQPNPIDPNIAQEGEIKLCTNFTEFKKFFGDFLLPTDDTKGQNTLAHAVYGFFRNGGTRCYITWITGESEVSEVLDKFEAIDEITIVAAPGNLSLRDDIKDHCEKMGDRIAVLDSDETIDLGSTGVVDTLKPFNSEYAALYFPWIQVFDPGSNSNIYVPPSGHIAGIYARVDGQRGVHKAPGNETILGALDLKYNLSKSKQDGLNPDGINCIRKLNGNIRVWGARTLGGDANTEFKYVNIRRHFNYLRDSIDKGTQWVVFEPNTPELWANIRRNISAFLVNEWRQGALFGTTPEEAFYVKCDAETNPPEVRDLGQVVTEIGVAVVKPAEFVIFRISQWDGSGQ
>NC_019678|2134732:2149324|2140699_2141086_-|WP_015117819.1|DBSCAN-SWA
MDVDFLGVGWTSPVELDENGQIKVAKYEDCVRQSIWMILSTSKGERVMRPNFGCNIHEKVFAPNSLGTVGQIVSDVRDALIEWEPRIDVLDVDTIPDSSQPNLILIQVNYQIRTTNNIFNLVYPFYLQ
>NC_019678|2134732:2149324|2143492_2144806_-|WP_015117823.1|DBSCAN-SWA
MTDVSSNWQDSLNTGLLNRLNRPLNQPGMMKISMSQRIINRCDRLLNRLPLLGQQIQRWGNVNTGVSNDVPIVYAQPVSATNQSGIESGENKFTSTSPVIQRKEKPIDNITPSLNLENQINQTSISSSQIPVVSSQAISEQLTESEEMPLQSNTKKENNSVPLIQRKSDNSQSSTIKSVDNIKNSENITPALGLENHNNQINQTSISSPQIPVVSSQAISEQITETGEMPLLQSFISASQQLPIVQIKQQNSDLFSSQLPVTNPLNTFTNSKQTQLENNSENIIYSKQENLGTEINLTNLPIVTTQPSTDKNNSIKKETSLNRNYSNSQKNHHLPVVTITPSINTPERNQSLPLTKNYSSSQITNNSQPNLSNNNSSSLPKVLPLPSPPAETIVSPLANQSNSNNLKKIDVDTIVNQVERKLMRRLVIESERRGKTR
>NC_019678|2134732:2149324|2145968_2146409_-|WP_015117826.1|tail|DBSCAN-SWA
MPTISNPHDPYFGYNFWVEWDGIVHAGFRECSGLTATRNATTYREGTDRALNQRQIPALNSFGNITLKRGITDNQELWEWHKKLQSGDTDRRNLSIILADDRGEEKLRWNLENCWPTTWNAPDLNGTSDEIAIETLELVHEGITVG
>NC_019678|2134732:2149324|2145572_2145935_-|WP_015117825.1|DBSCAN-SWA
MQQTEFPFILPQGYLDSEGNSHQEGIMRLSTAYDEITPLKDPRVQRNPGYLVIILLARVITKLGTLDQINTKIIEGLFSGDLVYLQDFYQRINQNGHSRLRVACPHCEGEFEVETIPVGE

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015117816.1|2134732_2136340_-|tail	phage tail protein	NA	NA	NA	NA
WP_015117817.1|2136320_2137259_-	hypothetical protein	NA	NA	NA	NA
WP_015117818.1|2137300_2140501_-|plate	baseplate J-like protein	NA	NA	NA	NA
WP_015117819.1|2140699_2141086_-	GPW/gp25 family protein	Q5GQU1	Synechococcus_phage	1.4e-08	31.2
WP_015117820.1|2141085_2141769_-	hypothetical protein	NA	NA	NA	NA
WP_015117821.1|2141765_2142830_-	phage late control D family protein	NA	NA	NA	NA
WP_015117822.1|2142842_2143496_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_015117823.1|2143492_2144806_-	hypothetical protein	NA	NA	NA	NA
WP_015117824.1|2144896_2145388_-|tail	phage tail protein	NA	NA	NA	NA
WP_015117825.1|2145572_2145935_-	hypothetical protein	NA	NA	NA	NA
WP_015117826.1|2145968_2146409_-|tail	phage tail protein	NA	NA	NA	NA
WP_015117827.1|2146591_2147716_-|tail	phage tail sheath family protein	J9PVC2	Bacillus_phage	6.2e-25	30.9
WP_015117828.1|2147878_2149324_-|tail	phage tail sheath family protein	J9PVC2	Bacillus_phage	1.5e-39	35.3

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NC_019678|5028608:5109614|DBSCAN-SWA
CATGAGCATCACATTCCCTAACTTATCAACAGAATTAGAAGATGTAGCTGAAAAAATCAGCCAATCATCTGTCAAAATCCGTCATGGCAATATTGGAATCGGCTCTGGTGTTGTTTGGAAATCAGACGGTTTGATTATCACTAACGCTCATGTTGCAGTCAGCGAAAAATTAACTGTAGAACTTTGCGATGGCAGAGAATTTCAGGCAGTAAGAACAAAAATCGATCCTACAAAAGATTTAGCCGCTTTAAAAATTGATGCTGATTGTGCAAATGTAAATCTAAATCCTGCAACTATAAGCGATCGCAAAAATCTGCGGGTTGGTGAAATCGTTTTAGCTGTAGGTAATCCTTTAGGAGACACCAATGCAGTTACAACTGGAATTATTTCTCAAATTCACCAAAATTCTGTAATTTCTGACATTCAACTGTATCCCGGCAACTCCGGAGGTGCAATGACTGATAGTAGCGGCAATATTATCGGCATTAACACCATGATTGCTTATGGTTTAGCAGTGGCAATATCAAGTCAAACAGTTGAAAGATTTTTGACAACTGTTAATGATAACGATAAACCGCGAAAACTGGGTGTAACCCTCAAGCCTTTAATAATAGGAACCAGCAAACAGCCTACTCTAGGTTTATTAGTTTTATCGGTAAATCGTCACAGTTATGCTGAAGCTTCGGGAATTCAAATTGGGGATATTTTGATTGGGGTTTCGGGAAGATTATTTCGACAACTTGACGATTTAACTAATTATCTCCAAGTTGGAAATCACTCAGAATTACAAATTATCAGAGGAGGAAAACAGATAAATTTGAACTTGGATTTCGACAACTATAAAACTACTTCCGAAGTGTAGCGTGCCTAATTCCCCATGCCCAGTGCCCAATTCCCAATCCAAATTATAGTCATTGCAGTTTCTCCAGTTATCAGAATGGGGTTGTCGGCAATGTTGGAAGATAATCCAAAATTCAAAGTACTCAAGAGTGTTGCGGATATTGATTCTCTCATAGATGATATTGCACAGCTACAGCCTGATGTAGTTTTGCTTGACTGGAATAGTCAAGATTATGAATCCATTTCACAATCGCAACAGTTTATGTCAGCAACTATTATTCTTGTAGATGAAATCGAAGATATTAACTTCGCAACAGTTTTAGCTGCTCGAATTAAAGGAATATTGCCCCACGACAGTACAGAATCCGAAATCATCGCAGCAGTTGAAGCCGTTGCTTCTGGGTTAGTAGTATTTCATCCCGATATAGTTGATAATTTACAGTTGCAAAAGCCAGCTAATTCACAACAACATGAAACATTAACCAATAGAGAAATTGAAGTTTTGCAAATGCTAACTTCCGGTTTGAGTAATAAAGCCGTAGCCCAACAGCTATATATTTCAGAGCATACCGTTAAATTTCACGTTTCCTCAATCTTTCAAAAGCTTAATGTTTCGACGCGCACCGAAGCTGTTGCTGTAGGCGTGAGGTTGGGGTTGATTATGTTGTAATATCATTTCTGTGAGGCTTGGTAATGGGTAATTGCTAATAGCCTAATGCACCGAAATTTTTATTTTGAATTATTTTTCTTTGGCTTGGGTTCCCAGTTGAAATCATGAGGGCAGCGACATTCTCCGCGATCGCAATTTATAACTAATACATCAGAACAGAAATTAATTAAGGTTCCATTGTCAAATTCTATCTTTAAACTACCTGGAGAACGAAACACTGCACCTTTATAACCAACAATTTGATATTGATGACTCATGTCGGATGGTTTTAAGAAATATGGTTTGGGATTAAAACTGGAATCTCCTTTCAAATCATTCAGACAAACTGCTTTTGTGATGTAGCGCTCTACAACCGGTTCTAATTTATCGTAAGCTGGAAAACCCATTCCGGGGAAATAAACATCTGAAATTTTTGCAATTTTTTTGGCTTGAGTGCAGTCAACCGTATAAGTTTTTGGATAAACATTTGGAAAAATATAATATACTATTGCTCCTAAAATTATCAAAATAGGAATACCAACAAAGCTCGATATTAATAAGACTTTTTTCATTCACCTGCATATTTACTAATAATCATTAGATGCTTCAAACCAATACCAATTCCCATACAAATTAAATACTTGATAATTAGCATTACCAAATGGACTCGCTTTACGATTGGGTTGATAGACAAAGCCATAGGAAGTTACATCAGGGCTAAATCCATTACCGATTGTTTTAACCCGAAAATATTTACCACCACCAGAATCAACTGCGTATTTATCAATTTTGTATAAACCAAGCTGCCGGTTTGATGCTGTTTTTCCGCTGGCTATAATTTGTTCAAATGCCGATTTCGATGCCAAAAATGCCAAACGACGGGGAATATAGAATTGAAGTAGTATACAAGATAAAAGTACTATCCCAGAAATTGCTCGAACAAGCCGCCAGGAAATATTAACTTTACTGAATAATCCCCGTCTACCTAAAACTATCAACGCAAAAATACCAACAACTATAAATATTGGTATGCAGATAATCGAAACCAATAAAAGTGCAAAAAATAAACTACCCAAAGCACCGGGATAAATGCTAATTGCAAGAATAGCAATACAAACAGTAATCGTTATAAATATTAATATTTTGCTTTCAATATTCATTTATGTTCCGATATCTTGCAGCATTATTAATAAGCCCTAAGTTATACTGTATTAGCACAACATTCCCCTAACTCTCAAACTCGAACCATGCGAACATTAGTAGTTGGCGATATTCATGGTTGTTATCAGGAACTTATTGAACTATTAGCCAAAGCCAAAATTACCGAATCAGATTGTTTGGTATCGCTGGGAGACATTGTAGATAGGGGCGCTGATTCGGTGAAGGTATATGATTTTCTCAGAAATCGTCCCAATACCATCGTGTTGATGGGCAATCACGAGCGCAAACACTTACGCAACACCCTTTCCTACTCTCAAGAAATCGTTAAACTGCAATTTGGCGATCGCTACGAAGAATTTCTAGAATGGGTAAGTAATTTACCCTATTACCACGAAACCGCAGAAGCAATTTTGGTTCATGCTGCCGTAGAAAATGGTATCCCAATCCAGAAGCAAAGGGAAGAAGTTTTATGCGGTTGTACTGCTGGTGAAAAGCATTTATCAAAACGCTACGGAGATACATATTGGAGCGAATTATATACTGGCGAAAAACCAGTAATTTTTGGTCATCATGTTGTCGGCGATAATCCGTTAATAGTTGCAGGAAAAGTTTACGGTATTGATACCGCCGCTTGTCATGGTGCAAGATTAACCGGATTAATTTTACCCAGCTTTGAAATTGTGCAGGTACAAGCTGCGAAAGATTATTGGCGTGAAGAAATTCCTAAGTGGCAATTACCCGTGATGATGGCTAAACCTTGGAATACTTATAAATGGGACAAAATCAAAGCTATTTGCAGCGATAGGGATTCGCGGAATCCGGAATTATCCAATTTTATGGTTAAGAAAGAGCAATGGATGAATAATTTACTAGCTCTTGCTCCCCAAATAACTACAAAGGTAGAAGAAAAATTAGCTGAATTAATTTCCCTTTACGGTGCCGATAACTTTAAAAAACAAGCTCGGAATTATAGTTATGCCACTCTTCTATATAAAGCAAATTCTAGCGGACTTGACAAAGATTTTCTCAAGCAAACTTTACGAACACCTTCGGAATGGTTGCAGGTAATGAAGGAGTTAGGAGTTAAGAGTTAGTGCTTTATCCCATAGAATATAGTGGGCTTGTAGTTGGGCGTTAGCCCTTCTTGAGGATATTTGAACTCAACCACAAAAACTAAGTAATTCTCTACAAAAATAAAAATAAGTGAATTTTCTCAGGTGGAATGTATAACAAAGCAATTACATTTGAGAAACATCGAAATTCATGCTGGGCTAATGTTAATCCGAATCTTTTTGGTTTCTTTGATTTCTTTGATACTTGTTAGCTGTCAATCAAAAGAACAAGAAAAACCAATTAATAATCTTGTTACTCCTAATCAAAGCGAAAAGCCCAATTCACAAGACTCCAAAATTGCTACCGGAAATACTAACCCGCTTAATCATTCTGGTAATTTTATGACTCTAACACCAACAGGACAAACGAATGCTCTCGATAATCCTCTCTACAAAATTAGTCTATATGTTGATGGAAAGTTCGTGGATAGCTTGATTGGTGTATCGGGAAGAAAATTTACGCAAACCAGAAACCGCCACCAAAGCGGAACTGAGGCTCCCTTACCAGATGGAAAATATACTGTTGCTACCTCTACAATTCCAGGTGCGATCGCTGAAGCAGGAGAGCATTTTTTAGCAATACAGCCTAAATTTAAAACTGGACGTTCAGCTTTAGGTTTTCATGTAGATCCATCTTTTGAAAAAAATAATGGGGAAGATGGTACGGCAGGATGTATTGGATTAACCAATAAAGAAGATTTAGATAAGCTATTGAGCTATGTTGCAAGCTATCAACCAAAATTTCTCGATGTCAAAATTTTAGATAATACTAACGGTAATTTAGCAAGCAAAGGTGAAGGTTAATCTTTGAAAGAGTTTAATTATAGGAAGTAATAAATAGCGAGTATAAATGAATGTTAACCTAAGAGTAAATGTATTCTGAAAGACTTTAATAATGTTTTTCACTTACATATTATTGAAACGGTTTATTTATGTTAGGTAAAAAAACTTATGCGAGAAAAACTACGTTTATCTCTAAGCGAAATCGCTAAGGAAGATGTGACTCAAAACGAACGAGAAGCAATCATTGAACTAATGATGATGGTAATGTATAGCGATAAAACCCTTAAGCTAACTGAAGATGAAGCAATTAAAGAATATGCAAGCAGTATAGAATGGGAATCACCTTTATCTTTAGAATTTTATTTTGCTAAAGTTACGCCAAAAATTAGAACTGCTTTATCAAATGATGAGAAAATGCATGTTTTCTTAAAAGATATCAATAGTCGTATTGAAACTGAAGTTGTCAAAGCTCAGGTTCTATTAGTCTGTAATGATTTAGCAATGGCTGATGCAGAATTTTCTGCGGAAGAGAAAGATTTGTTAAAAAACATTTCTCAGGTTTTTCAAATTAATTAGGGAAAATAAGTAAGTCGGCAGAAAAAACAGAACTATATAACAAAATGTAAACTACCCTTAAACCCTTATTCCCACTGCCGACTGCCGACTGCCTTGCCCTAATTACAATTTTCAACGCCAACCTACTTAGTCAGGAGTTAGGAGTTAGGAATTTATTTATTCCATTTGCTCCTTACTCCCTCAATAATTACGAATATTTAAACGGACACAATATAAACAAGAGTCATAAAGTACAAGCTAAATAAGTTTACGTTTTTTCAAAGTGCCATCCAAATTAAAAACAGGAAAATATTCTATATCAACCCAAGAATGTAACATCGCAGCCCAAAGAGTAATTCCCTCTAAAGCCTTCGCAATTAACTGTCTCCCTCGTAAAGACTGAGGATCTACAGGCTCAATATAGTCCATGCCCATAATACTATGATGTTCGTCCGCTTCCACATGAATATCAAAGTATGAATCCCCTGCACCAAGTTCATGCATTTTCGGTGCGACTGCTTTAAAAAAGTCATTTGAACAGCGCTCAATTCCGCTATTTATAGTCACTAGCCATTTAGCTCTATCCTGCTCTATGGCTAATTGATAAGCCAGATTAACGCAAGCATTAGTCTCTGGTGTAGGAATTATCTCTTCTATTTCTTGCGAATTATTTAATAGATTGTACTTGAGCATCCAATCCATCAACATTTGATGGTGATCTGCTTCACCATAAGCATGTTTAGCGTAGAATGGCATCATGTGATTTTCAGACATTGGGGTGTTCCCAAGCATTAATCCCATCACTTTCGGAAAAGTTGCAGAGTGATAATATAACTGTAGTGCCACTGGTTTAAACTCTGATGGAGAATGGATTTGTGCTACCCAATCAAAAAATGGCATTTGTTTCACTGCTTCGCTAGCACGAAAAATTGGTTCAGTTATCCATGCGTGTTTAATTCTTATCTTATCTATTTCAGCCGCATTTATAGCTTCGTAAGTTGGTGCATCTGCATACATCATATTTGACATGATTACTTCCTTTAAAAAAGAGATTGATGAGAGAGTCATTTTCGATTCAAATAACCAGAGCAAAGAGCTTTAGACTCAAAGGATAGCTTTGGCTATAGTTTTAGTGAATTTGGCTAACAGAGATGCAAGATGGCAAATCCAAATAATTAAAAGCAGCCGCAAAAATTTCGTCCGATAATAAATTCAGAGGCAAAAATAACTATTGATAATTTCGCAATTACAGATAAGACAACACTTACTTCTTCCACTTGGAAAGGTTACTTAAAGGAGCGGTGTCTTTTTTAAGGAATCACAAAAACAGGTATAAATAAGTCTGTTAGTAGAGTTATTCCTCTAAAGTCTTCAATGAGATTTTTTCTGTAATTAAATCAATAAAAATGCCTAAAACAAGGTCATTTACATCATTTTTATTGAAAATAGGTAAACGAAAAATTCCTTGAACTGATACTCAAAATTCAAAGCGAGCTAGTCTTTTTGCTCAATTTGAATGTAGTATAAACAACTCTTGGCTTTAGGTATTATTAAATATTTTCTTTATATTTTCAATAAGTAATTTTACTTAATTATTATTTTTTAGTAGTTTATATTTTACTGAATTAAAACTGAGTAGTAATTATAACTATAATCTTATGACTAAACTGATTAATCACTTGTGCTCTAAGAATGTTATTTTACCAACTTATTCGCTTTTATATTAATAATCAGACATTGAAAATCAACTTGTTTAACTAAAATAAATAAAACTTTGCCAAAACATATTAATAAGTAATATTACTGGGTTAGCAATAAATGATGACTCTATAAAAGTATGATTTTTTAATCAATAAGCATTCAAAATATTCTCAAATACCTTAAAAAATCAATGTTTCTCAAAAAGTAATAAATAATACTTAACTATGAATAATTAAGTAGCTTAAGACTTATATATCAAAAGGTAGGTTACATTTACACCGTATCGTGATTTACAAAAAGACTATTAACGATAACAGCGATCGCTATATAAAATATAATTAAATTTAATTTACAGTATTTTTAAATAAAGACGTTGCAATGCGGCGCAACGTCTCTAAATTACTTACGCTTTCCGATAACAATCAAACTGCATTGAAAATGTAGCCATACCGGAAGTTAAAGAACGCAAGTTACCGGAATATCCAAACATTTGCGTTAGTGGTACTTCAGCACGGATAATTGAATATCCTTGCATTGTTTGAGAACCCAACAGCAACCCCCTTCTTGAAGATAAATCTCCTTGAACTCTTCCCAAAAATTCATCTGGTGTCTCCACTTCAACTGACATAATCGGTTCGAGAAGATGAGGTTTCGCTTTCATAAAAGCTTGAGTGAATGCTTGCTGAGCAGCCATTCTAAAAGCAAATTCGGAAGAATCAACCATGTGATGGGAACCGTTTTCTAAAACAATTCTTACTCCCATCACCGGATATCCTTCTAACATTCCCAAATTCATCGCTTCGAGAAAACCTTTCTCTAATCCCCCAATATATTCTTTAGGAATCGCACCACCAAAGACTTTATTCTCAAATACAAACTGTTCTTCACAAGGCTCAATATACCCCACAACGTGAGCGTATTGACCGGGACCGCTAGTTTGTTTTTTCAATTTATAATCAAAGGTAGCTCTTTGCGAAATAGCTTCTCGATAAGATACTTTGGGTTTACCGACTGCAATATCTAAATAATATTCCCGCTTCATCCGCTCGATGTAAATTTCTAGGTGCAGTTCACCCATACCGGAAATCAATGTTTCATTTGACTCCTCATCTACATTTACGCGAAAGGTAGGATCTTCTTTTTGAAAGCGATTTAAAGCTTTGGAAATTTTATCCAAATCCTGATTTTTATTAACTTCAATCGCCAAAGTAATTACAGGCTCGGGTACGAATATATTTTCTAAAGATACTCGTATTTCTGACGAACAGAATGTATCGCCGGAAGCACATTCAACACCCAAAAGCGCCACAATATCCCCCGCAACAGCTTGTTTTATTTCTTCCCGCTTATTGGCGTGCATTCTTAATAATCTACCAACCTGCACCTTTTCCCCAGTACGGGAATTATAAATAGTGTCACCTTGGTTGAGAATACCCGAATAAACGCGGATATAAGTTAATTGTCCGAAAGACTCCACCGTCAATTTAAACGCTAAAGCAACCAAAGGTGCATCCAAATTCAAATTAATGTTTACAGATTCACCAGTCTCAAAAACTGTTGCGTTAACGAAATCTTTATCCACAGGAGAAGGTAAATATAGAGAAACAGCATCCAATAAATTCTGTACTCCCTTATTCTTAAAAGCCGAACCTATAAGTACGGGGACAAGCTCTAAATTCAAAGTTGCTTCGCGGATAGTTTTCCAAATCAACTCTTGAGAAACTTCTTCACCCTCTACTAATTTCCCCGTCATCTCTTCAGAAAACAAAGAAAGAGTATCAAGCATTTTTTCTCGTGCAGCTTCCGCTTCTTGCTTCAACTCATCGGCAATCTTTCGTTTAACCCAAATTTCGCCATTTTTACCTTCATAAAAATGAGCCTCCATTGCGATTAAATCGACAACCCCTTCAAACTGACTTTCAGCACCGATAGGATATTGCAACAACAATGCATTCAAATCCAAAGAATCATGCATTGCTTCCACAACTTTAAACGGATTCGCACCAGTTCGATCCATCTTGTTGATAAACGCTATACGAGGTACGCTATAACGCTTCATCTGTCTATCAACAGTAATCGACTGAGACTGCACACCAGCAACAGCACAAAGCACCATTACAGCACCATCGAGTACGCGCAAAGCCCGCTCGACTTCAATCGTAAAATCGATGTGTCCCGGAGTATCAATTAAATTTATCTGTGTATCTTGCCATTGACAGCTAGTAGCAGCCGAAGAGATGGTGATACCATGTTCCTTCTCCAAATCATCGAAGTCCATAGTGGCACCCTTACCACCTCCTCGTACTTCCTCAATTGCATGGATTCTACCCGTATAGAAGAGAATGCGCTCGCTCAATGTCGTCTTTCCAGAGTCGATGTGAGCAGATATACCGATATTTCGGATGCGCGTTCGGGGAACAACCATGATATTTTTCCTAATTTAATAAATGTTGTACATCTTTCCAAACCTCTCTCCTTCGAGAAGAGAGGCTTTGAAAAGGGAAGGAGTCGCAAAAGTCCTTATATTACAGTTATACTACATTTTTGATATAAGTCAATAGATTTTGGATGGAATCGGTCAAAATTCCTATATTTGGTCATACCTACAACTAATGTAGAGACGTAGCACTGCTACGTCTCCCCGTATTGTGATGAGTATCCAGAATTTTGTGAAATGGATTATTTGATTTTTGTTAGGAAGCTAATGAAAAAACGCAGAGAGAAGAAGTTATAGAGGTATGGTAATTTTATAGCGAGAAGTGAGTAGTTGTATTAATCTACAGAGTTAATCAAAAATCTAAAATCGCATGACTGGGCAAATTAATGACAGCTTAATATATCAAGGACGAGATTTTAGTATTGTGGCTGTGGATGGTAGAGAATTATTTAATCCCCAGCAATACGGTATCACTCCCGGAGTTGGTACGACTGCTTGCGGTCGGGGTTATTATTGCAGTTATGAAATTACAGATAATTCTTTGCAGTTAAAGCAGTTAATTGTATCTATTTATTCCGAACCTTTAGATAGAATTAGAATCAAACATGGGAAGAAAGAAATGCAAAACTTATTCGGAATCGTACCCAGCACAAAACCGAATTCAATTTCTCAAATTGTTTCTAGTCATTGCGCTACATATAATGAAGTTTACGCACCAATTAAATTTACAGGTAATTTATTAATCGCTAGAGATTTTATTCGCAGTTTATACGTTCATATGGGATTTCAAGCCGCTTATAAATATAAAGAAGTTTACGAATTAGTTTTTGATAAAGGTTTTTTAAATCAAAGTATAAATCGCTCTGAAGAAATGGCTATAATTCGAGATAAAATTATTTTGCTTTCCGAAAAGTCTGATAATTGGAAGCTTGATATTAATTGGAAGCTTGTGTGGAAGGGAAAAAATAGGATTTAAAATTATATTCAAGATTTCATACGTACATATTTAATATTGTAAATTAATCTAATTTTCCTCGATTAAAGATATTATTGTTATAAATCACTGTGCGGCAAATCTGTTTATTTAAGGAGTTAAAAGTAATGGAAAACCAAGAACTGTCCCTTATTCCACGAATTAACTGTGTACCCCGTTCGTTTGATTCAAATGCGCCAGTAAATTTCTATACTCCGCCTTTTATTACAAAGAGTGGAATGCAAAACGTATTTAACCATTTTGTTAATAGAGATAGTGATATTTATGTCGCAACTTATCCAAAGTCTGGCACAACTTGGACTATATCAATAATTGAGCATTTAATAAATAAAGTTCCCCCGAAAGGTATTTCAACTGGTGCTAGTACAGCAGAAGCTTGTTTGTGGTTAGATCGGGCTGCAAGTGTAGAAAACTGGCGTTCAACGTTTTCTCAATTGGAAAAGATGAAATCTCCAAGGTTTTTTAAATCCCATGCCAGTGTAGGTTTAATTAAACAACCTGCAAGAATAATTCAATGTATAAGACATCCTCTAGATACTTTTGTTTCTGCATGGCATCATACTAGAGGGAAAAAGCATCTTTTCTATTATAACGGGTCTTGGAGTCATTTCTTTTCAGAAATAGTATTACAAAGTAAATATGAAGGTGGTGATTGGTTTGATTATCACGAGGAATTTTTGCAAGCATCTAAAGCAGGGAAAATTGATGCATTATTTTTAAGGTATGAGGATATGAAAAAAGATAATGCTATTTCAGCTATACATAAACTTGCTGAGTTTATTGGAGTTGAATCTTATGACGCTGAAGAAATTTCGAGAGCAACTGATTTTAAGAGTATGAAACAAAAATCAATTACTGAGGGACATATTGATACTGAGGGAGAATTATCTGATGTTTTAGTTTCTCGCGAAGTTGGTGATAAGAATAATCCATCTAAAGCTCATATACGTAAAGGGATGGTTGGGGATTGGGTTAATTATTTAAGCGATGATGAGTTAGTTATGTGGAGAGATTATGTAAATAAAAAGAAAGATTATTGTCCTCATGTTGTTGATTTCTTTTCTTTAGATGATTTGCTTTGTAACTAAATATAAATAGATAGAAAAAGTATTTAAATAGCTCCTTAACTACTCCACAAAAAATAATTCTCTATAATCTCTTTCCTCTGCGTCCTTTGCGCGCCACTTGCTACAAGTCGGCGGCAGTCCCCTCAACGGAGGGAACCTCCGCACAGGGCTGCCTTGGGAACCCGCCCAACGCAGTGGCTTGTCTCTGCGGTTTTTTATTTGTAATTTTTTGCTTTTCACTTATAAAGTGACTCTGATGGTGCGTTACGCAGAGCGTACACACCCTACAATTACAATTGATTTAAAATTCGTTGATAAATCTGATAATTATCCTTACCAAAACAACAGAAAATAACTTTTAGCTGAGAATTTTTGTTTTTCAATTCTTCCGAACAAGTTTTCACCGCAATTTCAGCAGCTTTATCTTTAGGATAACCATAAATACCGGTGCTAATACAAGGAAAAGCCAATGATTCAAACTTTCGCTCAATAGCAATTTGTAATGATTTACGATAGCAATTCGCTAAAAGTTCTGGCTCTCCATTGTTACCACCTTGCCAAACTGGCCCGACTGTATGAATAATAAAATTTGCGGGTAAATTATATCCTTTAGTTAATTTCGCATCACCAGTTTTACATCCTCCTAAAGAACGACATTCCATAACAAGTTCTTTTCCTGCTGCTCTATGAATTGCTCCATCAACACCACTACCACCGAGTAAACTCGTATTGGCAGCATTAACTATGGCATTCACTTCTAACTTGGTAATGTCGTTTAAAATAACTTCCATATCCAATTACCAATTACCAATTACCAATTACCAATTACCAATTACTTATTATTAACTTCCCTTGCCAGTTTATCCATTTCTTGCTGCATTTGGGTGCAAACCAAGTTGTAACATTCATCTACATAATCGCGATCTTTCGATGCTTCTCTACCGTATTTTTCAAAAATAATTGGTTTACAAATGCGAGTATGTATTTGTACGGGAAACGGTATATTTGGTAAAGGTCCAATTGCTAAACCCCAAGGTAAACCTAAATATATGGGAAATACTCCTGGATCTAAATTATATAACCAAGGTAAACCCATAGTATTTAATTGTTTGATTATTTCGTAGAAATCACCCAACACAATTAAAGTTTCGTGAGCTCCTACAGAAATTGCAGGGATGATAGGAACTTCTTGTCTTAATGCTAATTTGATAAAACCTTTATTCCCAGCAAAATTGATATTGTAACGTTGGTTGTAGGGACGAAATAAATCATATTGTCCCCCCGGATATACTAAAACGCTCGCACCCCTTTTTAAAGCTGCATTTGCTGCTTTCGGATGAGCTGCGATCGCACCAGTTTTTTCACCTAATTTAGCAATGTCGGAATTAATTTTCCAGATATAGGGATGCATTAAACCATAGGCTAAACGTTCGGTTCCATACCTACGAAACCAATCGTACATCATCATAACCATATCGGGAGTTGCCATCCCCCCATTATGAGAACCAACTATTAATACTTGCTCTTGAGGAGGAATATTTTCCCAACCATCCGTTTTGACGCGAAAATAGTGGCGGTAAAACCACTCCCAAATTGGCATAAATGATTCAATAAATTTGGGATCTCTTTCATCTAAAGACCAACCTAATCTAGATTTTCTTTGCTGATTATTCATATTTATCATATATACGTTGTTCTTGCGAAAAGCGATGATTCACCACCTCTCATCATTAATGTTAAGCAAGTAAACGAAAACTAAACATATTTTTACAGTTAACAGTGAGCAGTTACCAGTTACCAGTGATATCAAGTATGGATAAATCAAAACATCTACCAATTCGAGCTTAAAAACTAGCATACTGAAGTGTCTAAGATTAAATATACAAGTAGTAACGAGAAATCATCCATTCTTCACTGTTCACTTTTAACTGTTAACTGTTTACCATACCTTTATATCGCTGAGCTAAATTTTTCTATGCATATGGGTACCCTAATGATAAGCAGGTTCGGCAAAATAAGGAAAATTATATATGAAAAGTGTTTTCAGTTGGTGGACTACTAGAGTTACAGTTATATCTACATTGTTAATTTTACTGTCGGGTAATAGTACCCAGGCAAACGATCCTGGAGCCTGTTTCATGACAACTGAGGATGGGAGAACCATTAATTTAGGAAGTCTTTGCGGTATTACACCTGTCAAACCTGTGGATACAGGAGTTTATCGAATTGATATCAAACGTCGAAGCGGGAATACTCCCATAGTAGATGTTACATTTAACGGCAAACAAACTTTTGAGATGATATTTGATACCGGTGCTAGCGGTACTTTGATTACTCAATCAATGGCAAATGCGTTACAAATAAAGCCTTCAGGTACTCTTCAAGCCAGTATCGCCGATGGTTCGGTAATAAAATTAAAGACGGGGCAGGTTAAATCAATTGGTGTTGGTGGTGCTAAGGTTAACAATGTTCGAGTCGCAATAGCCCCTAATGCAGACACCGGACTTTTAGGACACGATTTTTTTGGTAACTACGACGTAAAAATCCGACAAAATACGATTGAACTTTACCGTCGTTAGAAGACAGCAAGCTGTTAGTAGGTTGGGTGAAGCGGAGCGTAACCCAACACTTAACTAAGTACTTAGACAAAATTAATTATGTGTACTTAATTTTAACTATGAATAAAAATACGTTCGTAGTTGCGCTGTCTTTGCCATAATTAGAATGCGCTAAAGCGCAACTACAAACCTAAATCAAAGTATCTAAACTTGGCACATTCACCCAATTCGACGTTTCATTAGATTCGTGAGATTTATCCATCAACAACTGAGAATAAACTCCTTCACGTAAAGATGGTGTTGTGGATTCTCCGCTATTAATCGCTGCAACGAGTTGATCTACTACTCGTAAAAATCCGGAAATGCGTCCATCTGCATAATTTTTCGGAAATGTTAACCGATTGGGAATTTCGATTTCTGCAACTGGTTTACCTGCTTTTCCACCCCAAACTCGGAATCCATGTACGTAGTCTTTTTGATTTTCGCTAGCTAAAATTAAAGTCCCTTCATCTCCGTAAACTTCTATCGCATGGGTACGTGGTGCGAAAATCACCGCACTAATGGAAACTTGACAGGGGGTTCCATCGGCTAATTCCAACGTTAACGCACAGGTATCGTCTGTATTTACAGGTTTCATTTCCCCGGTTGTAGCATCTGGTCTTTGGGGAATTGCGGTGGTAAAATGAGCGTTGACTCGACGTACTTCTCCAAATAACCAGTGAATGTAGTCGAAGGTGTGGGAACCCAAAGAACCCAAAGCACCACCACCTTTCTCTTTTTGAGAATACCAATTCCAAGCGCGATCGGGATTAGCTCGGGAGGAACCAAACCAGTTAATGGTAATTAAACGCTTGTTCCCGACATAGTTTTGAGCTAATAATTCGCAAAATAGCAGCCATCCGGGTACGAAGCGAAATTCAAAGTCTACGGTAGCAGCTAAATTCTTTTCTTGAGCTATATGGTAAAGTTCTTTAGCTTCAGTGACATTTAAAGTAACTGGTTTTTCTAATAAAACATGCTTCCCGGCTTGTAAAACTTGTTTCGCCATTTCGTAATGCAGAAATGGGGGTGTTGATATGGCGACTGCTTGTACTTCGGGTAATTGGAGGATATCTGTAAGATTATCGCAAGCGTGGGGGATGTCGTTGGATTCAGCTATTTCTTTGGCTTTATCCAAATCCCGATTGTAAACGGCTACTACTTGAGTTTTAGGATGGGCTTTCAATCCGGGAATATGGACTTTTTTACCAAATCCGGTTCCCACCACAGCAACGCCAATTTCACCCTGTTGATTTTTTGATGCAGCAGTCATAAAAGTAAATTATATGTAGATAAGCGTTAATTTTATAATTTACAACGAATTGAGTTTTTTATTATTCACATCTTGTCTTGCACCATTCGCAACAAGCCAAAGAAACCCGGTTTTTGAAACTGGTGTAATACCATTTCTTTATAAAGATGCGCCGAATATAGCCCATGTAGATGGGCTTTGTTTGAATAGCCCTAGCCTTATAGGCTGCGGGCAATTTAGCGGTTCCCAATTCCTAATTCCCTAAATATTAAAATCGTAAAACTTCCCTATCATAATCTTCAGGAAGTGGTTCAATTTCCCAAACAATTCCTTCTCCCGGTTGTAGCATAACTTCTACAAAAAGTTCTTCAACTGCGGTTGCAGTAATATCCTCATTGTTGGGAAAAGCTTGTAAATCTTCGGTAAGCAATCTTAATTTAAAACCACCGGGGATAAAACCACCTGCCGCAGCGTTACGCAGTTGAAAACGCCAAATTATTCCTTCGAGTTCGTTTTTAGGAATAATTGAAAGGATATATTGCTTTCCCGCAATAGTTAATTGACGAGAAAGAATTTTTCCCGATTTTTCTATTTCTTCTAGATTACGAGCGCCTGCCATACTCGTTTCTAGATTAAAACTTCTCCAACCAAATTGTTCTGCTATTTGGGAAACCCCATTTTGCAACCAATCAATTACATGCCACTGTTGTGGTAATCCCAATCTTTTTTCATATAAACTGTTGCGATAACCCAACTGTTCGATGAAAGCTCCCCAAATGGTAAAAGGAATTTCCAAACGGGGGTTTAATATTTCTGGATTTCCCAAACGCAAAATTAAATTTTGGGCTTGTTGTGAAGTCAAATTTGCTAGGGGTGGGATTTGGCTACGGGTTATTTCTTGGGGACAAAATTCTTTACTTACCGTTAATACGCTTAAATCTGTAGTTACATCTGTTCTATCTAAGGAATAATTTCTAAAAACAGCATCATAACTCGAATTAATTTTAAGTTGAGCATGAGTAGAATAACCCCAAACTCGAACAAAACCTTCATCCGGTTGTACTTGTATTCCTAAATAATAATCCCCAACAAAACTAGGAATATCTACCCACTCTTGGGGAACCTGTAACTCGCTTAAATCAATATCTTCATTGGGAACTAACACAAATTTTGTGCCGTCACTAAGCGTAATTGAACATCCATTAACCAGCTCCCACAAGCTGGGTAATGCAGTGGTACTGGGCGAAAGCTTTGCCTGCTGAGCGAATTCTGACTCTAACCAGGGTAAGACTGCCAGAAGGCAAAGCTTATTCATATATGCTTGATAGCAATTTGCAGAATTAGAATAATTCCGGCTTTTATCCCAAGCTTGATTTTGAACGTTTAAAGGTATTTCCAAAATCAAGTCTGTTGGGGAAGTAAAGGTAAATAAGGAAATGTTGTTCATGATGAATTGGGAATTGGGAATTGGGAATTGGTAATGGGTAATGGGTAATTGGGCATTGATGATTCACACCCTGCAAGTGAACAACTGTTGACTGCTGACTGTTAACTGTTAACTGTTAACTGTTCGCTGTAATAACTTTGCAGCCATTCCTCCATTACGGTGCTGGTAGTTTTTAATATGTCTGATGTTAAAGAAATATGCAGTTTTTCTTGACTCCATTTTGCAAAGGAGCGTAGTAATGTTTCTTTGGTTTTACTTAATCTTCTAGAAACTGTATATTGTTTGACTTCTAGCTGTTTGGCTATTTGCTGTTGAGTTAAACCTTCCGCGTAATAAAGCTGTAAAATTTGCTGATTTTGTATATCTAATTGAGTAATTGCACTTATTAATACGGTATTTATCTCGGATTGTTGAGAAACTTTTTTTTGTTCTTCTTCTGCGGCAATAATTTCATTTAATAAAGATTCTTCGTTCGCTGCAATATTATCTACCCATTCAAATGAATCTTCACCAACCGGAGCATTAATGGAAGTTACAGTCGGATAAAGATATTTACGGATAGAAGTGGCACAATTGAGCAGCCAGGTTTCCACAGTTGAAGAATCAATTACTGTATTCGTTTGTTTCTCATAGGTTTGAGCGATCGCCAACCAAATTGTGTCGTCAGGGCGGGGAAGCTGCCTGGTGCTGTTGCTTTGGGTTGGTACGTACAAAGTCTTAAAACAATTCCAAACCAGCACATAATTAGCAATTGTATCTTTTGGCAAACCCGACTCTTGCAAAGATTCAATCAAACGCTTCTGACTAGTTTTGCGTAACAAACTCCAAACCGAACAAATATCAACTTCGTGACGCTGACGCAATGTATCGCGGATAATACTTCCAAAAGCAGCACTAGCGTAGTTTTTCAGTCGATAACCGGAATTTAAATTAAACCCTTTGAGAACTTTATCAAACTTTGCGATCGCGACTTGAAAGCAGTCGGAAAGATTGTACTGAATATTCGCAAATGTGTTTGCTGCTTTTAACGAACTCCAGTAACAACTTTCCTGTAAATAAGCTAAGAGATGTTCTTGGGCAATTGGCTGGGGACTAATTCGCCACATTTTATACCAGTAAAGCGCCCAAAAATTATCGGAAGTTTCCGCTTGTTTTTTTTCTAGACGATTAGACATGCTCCGACGCAGTTTACCATCAGTTACCCAACCCCGAAAACGGTCTGCATCAAATTGTAAGAAAGTGGAAAATATCTCAACAAGATTATTTCTCGATTGCATAAAACAATACAAGCCAGTATGGGAAATATAGTATAAGAGCTATAGCGCTACAAATTCAAGAAGAACTCTGCTGCAAGTAATCAAGAGTATAGCAACCGAGCAATTTCTGAATTGATCGAAATAATTTTACAAATATCGGCATAAATTTTTGAACCTATACGTATCTAGATTATAGACAGTCTAAAAGCTATTAATGAGGTTTAAATATGTTTGTTAATACTATAAAGTCAGTGGTTTTCGGCAGCATGCTAATGCTTTCTACAGCATCAGTTGCACTCGCTCAACCGTCTCTACCCGCGCCTGAGTTTCAGATTAAGCCAGCATCAAAGTTTACTTGCGCTCCTCATACAAGAACTTATATTGTTAAATCTTTGACAAATGCTAAAGGTAAAGGTATCCGTTGCGTAAAATTTGCTAATGGCAGCAGAAGAAACCGTCTTCCTCGGATTGCTTGGTATGGAGAAGGTAACTGGAGCGGTAGAACTTATCGTCACGTCGGACAGGCATTTTACAGAGGTAGGAATCTGATTGGTTTTGCTTCCGATATGCACGGCAATGGAGAATATTTCAACGGTAACTTTAACGGTAATTTGAAATTACAGTTTGTTAGTGGTTCCAAAATTAGAGTTACTGGTGCGTGGAATGAAGAATGGATTCCAGTGAAATCTACTTCCTATAAGCCTTTACCCAGACCTAAAACTTGCGGAAATTACTTCGACCAGTATAAAGTTTCTGACTTAACAGGGAAGCGTCGAGGTTCTGGATTGCGTTGCGTGCTTCGCGTCGGACGTAAAAATACTACTTGGTTTGGTAACGGTAACTGGGGAAGAAGTACTTACTCTCATATCGGTACTCGCGGATATAAAGGTTATGGTGCCAGCGATATCTGCGATACTCCTTTCGGTCCAATTTGCAATAAATTTGCTTTCGGTTCCTTGAAGCTTACTCCTGCGGGATCTGGTTTCAATGTTACGGGTGCCTGGAGTGAAAAATGGCGTAAGTAGTTTACAATTTTTTCCCTTCTCCTTAACAAGGAGAGGGGTGCCCGTCAGGGCGGGGTGAGGTTTCAGAAGATTGCAAATTAAATCTATTAGGTAAGTAGTAGGTGGATTTATATAACATCCCTTCCACCGTGACTTTTTAATAAACGTTCCATTTCCTCATGATTCCATTCTTTTGCTTCTGAAAGAGGAGTGTCTCCGAGGCAAGTGATACTATTAACTTTTGCACCATTGTTTATAAGAAATTCAGCCATTTCTAAATGACCTTTTGATGCTGCATGATGCAACGGTGTTTTACCATCTGCATCGCGAGCATTTATTGGTAAACCATTTTTTAATAAAAACTCTGCAATTTCTATCAAAATATCTTGGGACGTGAGAACCCCTGGTTTATAACCAGGGGATGAAACGGACAGGTAAAGTTTTAACTTTCCGTGTTTCTTTTATTTACTAGTTTGGTTCTCAATATACTTACGAATAACGTCGGTACTTACTTGTCCTGTAGTAGCTACAAAGTAACTAGGACTCCACAAAGTAGGTAATTTTTTTAACTGTGGATATTCCTTCCTTAGAATATTAGATGCTCTACCCTTAACCCACTTTGCAATTTGAGAAGCTGACTCATGTGGCGGTGAGTTGATAAACATATGTACATGATCTGGCATCACTTCAAGAGCGATTAATCTCCAGCCATGTTCTTTTACTAACTCAAAAATAATTTCCTGTAGCCGCATAGCGATTTCATTAACTAATACTGCTTTACGTCTTTTTGGGACAAACACAAAGTGATAATTTATCGATGACACGGATTTTTCAGCCCTTCTGTATTCATAATCTGACGCTGACAACTTAGCCATTTTATATCAGGGTTTTTTGTTGATTATTTATGTTGAATCAACTATATTAATAAACAAGGAGGTGGTCAAGTGTACAAAACAGTTCCAATAAAAGCAAAATTTACGGATGAAGAAAAAGCTTTCTGGGTAGATCAGTGTGAGCATTCAAACAGTTTATATAACTCTGCTATTTATCTGGCACGCCAGAATCATTATGCAATGCTACTTGAAAGAAAGGCTAATACAACTTACTGGTGTGGAGATGAACTTAGAAGTGGTTGGAAAACTTACAGATTAGAAACTAATTATTATCATTTAGATAAACAGCTTAAAACTTGCATTCACTACTTTTCATTGGCTGCACAAGCTGCACAACAAACATTAAAGTTAGTAGGAGAATCAATAACTAGTTACAATAAATTAGTGGATAAGTATTACTTAGGAGATGGCAGTAGGCCATCAATTCCCAAGTACAGAAAGTCTGGTGGTTTATTCGCAGTTACGTTCCCAAAACAAGCCTTGGCTTGTCATAATGGTTATATTTATCCCTCAATCAGTAAAGCAACAAAGCCTGAATTAATAACATCAATTAAGCTTATTTTGCCCGAATTTATTAGCTTTGATTGGATTAAAGAAGTAATTATTCGTCCTAGTCGTGGAGAGTTTTGGGTTGATTGGGTGATAGACGATGGTAAACAGCCAATTATAAATAATAAGAGTCTTAACTACAATCATGCAATTAGCATTGATCACGGTGTAAAGTTTTGGTTGTCAGCAGTTACTACCCTTGGTAAAAGTTTTATTGTTGAATCTCCACAGCTAAAAACTGCACTCCATAAATATCGAAATCAAGTACAGCAACATAAGAAAAACAAACCTAGTAGATACTGGGACAATTACCTTGATAGAATCACAGCAAAACGCAATTTACAAGTCAGAGATGCAGTAAATAAAGCCGCTAGGTTTATCATCAATAAATGCTTAAAAGACGGTATCGGGAATTTAGTAATTGGTTGGAATGAGGGAAATAAAACCAACATTAATATTGGTAGAAACAATAATTATGAAGTTGTTTCAATGCCAACCAAAAGACTTATTGAGAGGTTAAGACAATTGTGTGAAGAATATGGTATTAGATTCCACATAACCACTGAGGAGTATACTTCTAAAGCTTCTTTTATTGATAATGATGAATTACATCAATACGGTGCAAAACCCATAGAATGGAAGCCATCAGGTAAAAGAATTAGTAGAGATGTATACCGCACAAAAGACGGTTTATTGATTCATGCAGATTTAAATGCAGCATCTAACATTCTACGAAAGGTTGCCGACCAGATTTTTATTAACTCCGGCATCGCAAAACTAGCTTTTGAAATAATTAAACGGGGTGCTTTGACACACCCCAAACGGTACGATATTTTTAGTAATCTAAAAAGGTCTTATCGCAAGCAAACAATGTCACGCAGTATGTCTTTAGACTACGGAGTGACAACTGCTTAGAATCCCAGTTTTTTTCAAAGCTGGGAGATGTCAAATATCCTTTGCTTGCAGCTAAATGTAACGAATCAAGGCTATTAAAATTGATTCCTTTTCTTGTTAATAATTCCACAATCTGTATTTTATTTTGACAAATAGCTAAGCGTAGTGGATGACTACCACTATCATGATTTATATACGCACCACGCTCAATAAGTAATTCAGCAATTTCTAAATGATTGTATCTTATTGCACAATCTAAAGGTCTTCCGCCTCCAGAATAAAGACTAATATCCGCACCATTATCTAAAAGCAAGCTGACTATTTCTTTATGATTACCCATTACAGCTAGATTCAATGGAGTCCCACCTCTACGTGTGGAATTGATTTGAACATTTTGTTTTATAAACTTTTCCACAGCATCGATATCTCCTCTAAAAGCAGCAAAGTGAATTCCAACCACAGCACCACGAGCCAGAAAAAATTCAACAAGTTCGGTATGATTGTTCGTTGCTGCTTCTAATAATGGATTTGAACCATTTTCTTCGTTTAATCCCTGGTTAATATTTGCTCCATTATTAACCAGAAATTCAGCCATTTCCTTATTACCTTCACAAACAGCTAAAAAAAGTGGTGTACCTCCAAAAACTTCGATATCAACATCAACACCTTTTTTTTAACATTGTTTTACCTTTTCAATATCACCATTAATAACTCCATCACGTATTTGAGTGACTGGATTGGTACGAATTCGCCAAATAATTAGCGCTCCTGTAATAGCAAGTAATACGTAAAATATTAAAGCTTGAATAGTCATTTGATAAAAACACCCCTATATATAAAAGCTCAGTTTAACCGTTTTTTTTAATAAAATTTCTAGGAATCATCTTTTTTGTAGAGTGTTTGACGCTTTGAAAAACTTTCTAAGCATTAAATGTTTTGTAGATAAGTGGTGCGTTACGCTCCGCGATAACGCACCCTACAAATAAAACCCTAATCTCTCTATAACTTTCTTCCTCTGCGGTTTTTTTCTCCCAAAAACTATAACTCAACAAAAAAACTCTCAAAAAATATTCCGAAAACCCCGCATAAAAATCCCAGCACAAACGTAATAGATATTAGAAGGGATTCAAACCCAAACACACTAAAACTAAACAATATTTCTAGGAGTTTAAATATGTTAAAGCGTTCCTTGGCTGTTGCGGCTGTTGGTACAGTATTAAGCATCGGTTCTATTAGCCCCTCTTTGGCTGCACCCCGCGACTTCGTTGGTACCTGGGTAAATACAAATTCTAATACTCGCGGAATTACTAAGCTGGTTGTTAGAAGAGTTTCTGGAAACAGATTAATTGTCAGAACATACGGTAGCTGTAGCCCCAGAGATTGCGATTGGGGTAGAGCTAGACTAACTACCTACGGTAACAGCGTTCAAGATAGAAATCATCGCTCTGCTACTACTACCTATAACAAGAGTTTTGCAAATACTTTGTTGACTATTAACCTCAGAGGTAGAGATAGATTGAGTTTACAAAGCTTTACCCAGTTCAAAGATAACAGTAACAGACAAAATTACACATCTAGAGCCGTTTTCCGCAAGCGTTAATTTTTTCGGGTAAAACTAGAATAAATCGAAAAAATCGTATATTTTATTAACGGGTAAAGTCAGTATTATCTAACTGATTTTGTCCGATTTTTCTATTTAAAGAAAAACAAAGCAGGGGGTAGCTACATTTTATTTAATCAAAAGGTATTAAAATGTCTCCAATTGGTATTGCAACCAGTCGTTTAAACTACAAAAATAAAGAAAGTGCAGCCAAATTATGGTTGCTCTTGATTGGGGTGAACCAATATCAGGATGAACAAATTCCTAACCTGCGTTATTCAGCGGTAGATTGTCAGGGTTTAAGTTCGGCTTTACAAGATACAACAGATAAATTCTCCCGAAAAGAAGCTAATATATATCACGATTCAACTCCTCGAACTCCTTGTCTAGAAAATATACGTACTTCTCTACAAAAAATTATTGTTGATGCAAAACCCCATGATACCGTTTTATTTTATTTTTCCGGTCATGGTGTTCTCGAATCATCTACTAATCAAGCCTTTTTATGTTTAAGAGACACCTATAAATCAAAATTACTTGATACGGGTTTAGCTGTCAGCGAACTTTTACAATCTTTGAATAATTGTGCGGCAAAAAATCAATTAGTATGGCTTGATGCTTGTCATAGTGGCGGTATGACGTTAAGAGGAGTAACGCCACAATTAGTTGAAATATTACAGCAAAATGCCGTTAATAGTAAAGGTTTTTATGCATTGCTTTCCTGCGATACCAATCAACAGTCTTGGGAATTTCCAGAATTAGGACATGGAGTATTTACTTATTTTTTAATGCGGGGTTTGCTTGGTGGGGCGGCTAACTCGCAAGGTGTAATTTCTGCGGATGGTTTATATCAATATGTTTATTATCAAACTCTCCAGTATGTCGATAAAACCAACCAGCAGTTAAGGCTAATTAATCAGCAGAAACAAGCTAAGGGGAATACTTTACTACAACGGGAATATTCTTTACAAACTCCAAAAAGGATTGTGGAAGGAGTGGGAGAAATAATTTTGGCGAAAGCTCCCCCAAAAAATGCGCTTTCAGTCAATAATCGTGTCGGTTTAGTGATTGAAGGATTCTCGGATAGCCAAGAAACTTTAGAAATTAGTAAACTGTTGGGAAGCGTAGGAAATTTCCAGCTTGAATATTTACAAGCAGCAAAATTATCCGCCCAAAAACTAAAAGAAATAATTAGCGATCGCTTAAAAACAAATGCCGCAGAAACGGTTTTACTTTATCTGCGGGGAAGCATAGAAGAAACTTCTACTTGGGAGGGATTGATATTAGGGGAAAATATCCGCATCAAACGTTCTTGGTTAAAACATTTATTGCACGATATTGCTGCCAAGCAAATTGTTATTCTAGATTGTCCCAATTTTGATTCAAATTCTTCTAACGTACAAGAATGGTTAGAAGATTTACAAATTGATTCCCAGCAAGGGCAATGTTTAGTAGTCTCTGCTGGATCGCAATTTTCTCAGATTTTACTCGATACTTTGACAAAAACTCCTGCAACAACTGGATTATCTGCCGCTGGATGCATATCGCAACTACAATTACAGTTAGCAGGTAGCGACAATTTGAAAGTATGGCTTTCCGGTACCCAAGGAATTATTGAAATTATTCCCGGTAAAAGCGAATTTACATCTAGAAATCAAAAGCAAGCCATTGATTTAAACATATGTCCCTATATGGGTTTAAATGCTTTTTCTCCAGAAGATGCCAGGTACTTTTGCGGTAGAGAAAATTTAACTCAGCAACTAATTTATCAAGTCAAAAACAATCCCTTTGTTGCAGTTGTTGGTGCTTCCGGTAGCGGTAAGTCTTCTTTAGTGCAAGCCGGTTTAATTCCTACGTTAAGAAAAGGAAAACAAATACCTAACAGCGAAAAGTGGTTAATTAAAATTTTACGCCCAGGCAATAATCCTTTAGAAACAGTTGCCGCAACATTTTCTTTCTTTCATCCCCTTTCTCCCGAAAACTTTGTTTACCGATTGCGAAAGATTCCCCAAACAATTACAGTTTTAGTCATAGATCAGTTTGAAGAATTATTTACTCTGGCATCAGTAAAAGAAAGAGTAAAATTTTTAGAAATATTATTATCTGCGGTGCAATATGCATCGGATAGATTTAAATTAATTATTACTTTAAGAGCCGATTTTGTTGCTTCTTGTTTGGAAGTTACCAGCTTAACAAAATTATTGCAGGATTCAAGTTTATTAGTTCCACCTCAGTTAAATCAAGATAATTATCGTCAGGTGATAGTTAAACCAGCCGAGCAGGTAGGATTAAAAGTTGAACCGGAATTAACTGAGATACTGCTGCGAGATTTAGATAATTCTGTTGGCGATTTACCTTTATTAGAATTTGTTTTAGAGCAGTTATGGCAGCATCGTCATCAAGGAGAGTTAACTTTAAAAGCATATGAAGAAAAATTAGGTGGAATAAAAGGTGCATTAGAACGTTCATCTCAAGCTGTATACGACAATTTGTCTCCTTCAGCCCAAGAATGTGCAAAATGGATTTTTCTTTCTTTAACTCAATTGGGAGAAGGTAGGGAAGATACTAGAAGAAGAATATTTAAATCTGACTTAATAGTTAAAAAATTCCACGCAGAATTAGTTGAGAAAACACTGGCTGCTTTTGTGGCTGTAAAGTTGATTGTTGTTGGTAATGAAGATGGGGAGAAAACCGAGCTTTGTGCAAAATCTAATTCCATAACAGTAGAAGTCGCTCACGAAATTTTAATTCGTTATTGGAATACTTTACGGGGTTGGCTGGAGGAAAATCGCAGTCGTCTGCGTTTGCAACGTCAAGTTTCTCAAGCTGCTCAACTGTGGAAACAAAATGGGGAAAATAACGATTTTTTGTTGCAGGGTGTGCGCTTGGCTGAAGCGGAAGATATTTACCTTCAGTATACGGATGAGTTATCTAGTAATGTCAAACAGTTTATAGAAGCTTGTTTACAGCAAAGAAAGTATCAACAATTTGAAGAAAAAAGAAGATTGCGACGGGCACAAAGGGGTTTAGTTGCATTGAGTATTCTAGGTATTGCTTCTTGCGGTTTTGCTGGTTTGGCTTATCTTCAAGGCAGGGAAGCGAATATACGAGAGATTCAAGCTTTAAATTCTTCGTCGAAAGCTAATTTATTATCGGATAGGCAGCTAGAAACTTTACTTAATAGTGTGGAAGCTGGAAAGCAGTTGCAAAAAACTATTGCGGTACCGTCACCGATACGCTATCAAACATTGAATGCGCTGCAACAGATAATGTCAAAAATTCGCGAAAAAAACCGCTTTCAAGGACATACTTCTTGGGTAAATTCAGTTAGTTTTTCTCCCGACGGTAAAATAATTGCTTCTGCTAGCAGCGATAATACTGTTAAATTATGGCGGCGAGATGGCAAATTAGTTAATACTTTAGTTGCTCACAATGCTGGAGTAAATTCTGTCAGTTTTTCTCCCGATGGTAGATTTATTGCTACTGCTGGTGACGATGAAACAGTTAAATTATGGGACGCTGTAGGTAATTTACTCAAAAGTTTTCGGGCACATGATAGTGGAATTAACAGTATTAATTTTTCTAAGGATGGTGAAAAAATCATCTCTGGAAGTAACGATACTAAGATAAAAATTTGGAATAGAAATGGCAAACTGTTAAATACTTTGTCAGGACATCTTGAAAGTGTAAATCAAGCTATTTATTCCGAAGATAATCAAATGATAGTTTCTGCTGGTAATGACAATACTGTTAAACTTTGGAGTACTGACGGTAAATTATTAAAAACTTTGCAGGGACATGACAAAGATGTGTTTAGCGTTAGCTTTAGTCCCAACGGACAAATTATTGCTTCTACAAGCGATGACGAAACTATTAAGTTATGGAGTCGTAACGGGGATTTATTAAATACCGTGCCTATGGGGAAAACTATCAAAATTTGGAATCAAAATAATACTTTGACCGATACTTTTATCAACCATAACAATCAAATTAATAGTATCAGTTTGAGTCCAGGTGGTAATTTTCTAGCTACCGCCAGTGATGATTATACAGTACGACTGTGGAATATCAATAGCATATTAACAAACACTTTTTTCGGACATACAGATGAAGTTACTAGCGTCAAATTTACTAAAAATGGTCAAGAAATAAATTCTGTTAGCGATGACGGCACCATGAAAATTTGGCGCAAAGATGGTAAATTACTTAAAACTTTGTCTGCACCGATAAATAACGTTACTAGCTTTAATATTAGTCCCGATAAAAAAATTGTTTTTGGTAGTGACGATGGAATTTTAACTATTTGGAGTGAGGATAATCGCTTAATACATACCTTACCAGCACATCGCGGTTGGATAATTAATATAAACTTTAGTCCCGACGGTAAAGTATTTGCTTCATCTGGGATTGATGGCACAATTAAACTTTGGACTCGTGATGGTAAATTAGTCAAAGTTCTTAACGATCATAATGGTTGGGTTACGAAAGTTAAATTTAGCCCCGACGGTAAAATTATTGCTTCTGCTGGTGCCGATAACACCGTCAAAATTTGGAGTCGTGACGGTAAATTGCTGCACAATCTTACCGCACATACTAATAGCGTTTGGGATATCAATTTTAGCCCCGATAGTAATATGCTTGCTTCCGCTTCCGCCGATAAAACCATCAAAATTTGGCAGCGCAACGGCAAATTAATCGAAACTCTTAACGGACACGCTGATTCTATTACTAGCGTTGTGTTTTCCCCTGACGGTAAGGCGATCGCCTCTAGCAGCGATGACGATACGGTAAAATTATGGAGTAGCAAAAACGGTCAATTAATTAAAACCATTAAGGGACATAATGGTAACGTCAGGAGCGTAGATTTCAGCCCAGACGGTAAAACTCTTGTTACCGCTAGTGCCGATAAAACTGTGAAGCTTTGGAATTTAGAAAAAGTAGAACTCCAACCCTTAAAATTAAATGCTTTACTCGCACAAGGATGTCATTGGTTGGATGACTACCTAAAATGGAACAGCAACGTTAGCGAATGGGATAAGCAGGTTTGTTCCTGAGTTGAAGTTTATCTTTGATTAAAGGATTTCTCCCAGGTGTTGAATGTGGTAAATATCGTGTCGGTGTATAGTTACCGTAACCAGGTTTTTTAGGCATACGAGCCGGAGGTAGCTGATGATTTATACCTTCCTCTACTGGTGGAATCCAACGTGGTGGTGGAGGCATTGGTCTGATGCCACCTTGTTCTGGATTTAACATGGCATCCATTGAATTATCTAGCTTGACAGCTTGATATTTAACTTTATGGATTTTACCCGATGCAATGTTCTTTACCGCGTTTTTCAAACCAGGAAAGGCAGTTAAGAGAATTGTTGATACTGCAATTGTTGAACCAAGAATTTGCCTTTTCATATTCACCGCTCGCGACAACTTAGAAATTCAATGTGCCCATAGCAGCTTTCGATTGAGTCCAATACATCCGCAATCTCATCTTCTTTTTTTTCCAAGATGAGGTATAGTTTATAAATTACCCAAATGAAAACCGCTATATATACTTAGCTACCAACTGCGATCGCAGTATTTCAGGAAATATTTATAATTCAGACTTCTATTTATATCCTGAGTTCTTATATATACGCAATTCATCGGAAGGCATGAATTTGTTTGAGGATTAAAAAAACCGCTACAATTACCTTTCAACAAATCAACAACTGACATAAATTTTCGTTTACATACATTAAAATATATCAAACTATGCTAATTATACTGTATTCAAATCTGCTCTGTCATTAGTTCTTTACTAAAATAAATGCTTGCATCTTGTATATCAAATTCAATCTGTTTATAGAAACCTGGTTTCTTCCTCATGGCATATAAAATTTTATGTATGTGCGCTTAGAAAAACAGGTTTATGAATTAAGGAATCATGTAAAAATAACTTGAACAATTAGCCAGAAAGTTAAATAATTATAATGTAGTGTAAATTGCAGTGTTAGATGCCTGATAATCACAAAGTTAAAATAATTCAAGACAAATATGATTCTTTATCTCCTTATCTGAACGAGAAAACACGGCGTATCTGGGCAGCAATTGAAGCCCAAAGCCTTGGGTGGGGAGGTGTAACAGCAGTTGCGATCGCAACTGGTTTATCTCGAACTACAATTCATAGTGGAATTGATTTGCTGTCAAAATTGGATGAAGTAAAAACGGAGGATGAGAGTACTCGAATCCGCACAGTAGGTGGTGGACGGAAACTGCTCGAAGAAAAAGATGCGATGCTGCTATCAGATTTAGAATCATTGCTTGAACCAATGACTTTAGGAGACCCAGAATCACCGATAAAATGGACGAATAAAAGTGTTGTAAAACTTGCTGCTGCACTTAAGGAGGGAGGGCATAGTATTAGTCCAAAAAGTGTTTACAACTTACTTGAATCTCTTGGCTACAGCCTACAATCAAATCGTAAGACTCGTGATGGTTCATCTCATGAGGATAGAGACGACCAGTTTTTATATATTTCTAACCAAGTCAAATATTTTCAGTCCCACAACGAACCTGTAATTTCAGTTGATACTAAGAAAAAAGAGTTAATCGGAAACTTTAAAAATCCTGGAACTGAATGGTGTGACTCCGAACAGCCAGTTGAAAGTAAGGATGCATGACTTTGTTGACCCTAACGCCGGTAAGGCAATTCCCTATGGAATTTATGATCTAACCTTAAATAAAGGATGGGTTAATGTCGGCATTGACCATGACACCGCAGAGTTTGCGGTCGAGTCTATTCGCCATTGGTGGTACTCAATGGGTAATCTTTTATATCCAAAGTCTGAGCATATAATGATTACAGCAGATTCGGGTGGTAGCAATAGTTATCGTTCTCGACTATGGAAGTTAAAGCTGCAAGAGTTTGCAACCGAAATTGGTAAAAGTATTCATGTTTGCCATTTTCCTCCTGGTACAAGTAAATGGAACAAAATAGAGCATCGTTTATTTTGTCACATCACAACTAACTGGCGAGGTCGACCATTAACTAGCTTACAAGTAGTGATTAATCTGATTGGCAATACTACCACTACACAGGGCTTGGTTGTCGAAGCTCGACTAGACGAAAACCTCTATCAAACAGGAATTAAAGTTACAGATAAAGAGCTTGATAATATTGCCATTGAACGAAACTCTTTTCATGGTGAGTGGAACTACATTATTAAACCGCAGATTTCTGGTTAATTGTTCAAGTTATTTTTACATGAATCCTAAGTAAATATGCTTAAAACTTTCAATTTATCCTTCGGTCGCTGAAAAACAATAGAACCTGCTTTAAGGTCAAAACCTGCACTTTTTTAAATTCCGATTATACAAATAGTCTAATAAAATTTAGAGATGTAGCAATACCACATCTCTTTTCGCCATACCATAGTTACTAACAAAGAATAGCAGAAGCTTGATTATTTCGACAAAGATATTATTTGCTCTCCACTAATTTTGATAAAGTAGAAACACCAAGAAATAATCCCAATGAATTTCAAACTATCTTCAAAAAAATAACCATCATCTACTTTAAATAAATAGCTACTTGCAGGGATTAATTGGTCAACAATAATTGATAACAACAGAAATGTTATTGCTATTATAAATATTGTAAAATAACTATTAAAAATAATTTTTCTGAACTTAAACAAACAATAGGCTGTAATGATTGCATAGGCAAGAAAAGTTACTTTTTCAGATATTTTCAAAAGCACGGGAAAAACTGTTTCATGCAGCATAAAGAAATCATCTAGTGCTAGCAACAGCGTTAAACTGCCGAAAGATAACAGAAACTTAGAGTATTTATGGTTTTTATTGACGTTAATTAATACAGTTCCACAGAATAATAATATTGCGGCTGTAGCTGACCATAGAAAAATTCCTATATTTGAAAACAACCCATAATAAGGTTTTACAGAAGCAGCTACAAACACGTCTCTGAATAATATAGAAAAACTAACTGCTGGCTGCAACCATGCAATAAGTAACATAACAAATGCTACAAGATATATCGTAAAAGGGATAATATTTGTCTGCTTAAGCCGGGTTGTTTGTAATTGTTTATCCCCAAAATTTGGTTTTAATAATTTATTATTCATCTGAATATTGTCTAAGGATTATTAAAAGGTTAAGCTTATGTTAACTAACCTCTTACGTATTTTTACCATCTTCATTTGATTTTGGTAATAATTTCAACAATGCTTTATTTTTTAGATAATAATCTCTATCGGGAGATTACCTAAGTAGAAAAAGTTGCAAAATAATCTCCGAATTATTACTGAAAAAGTTATAACCTTTGGTAGAAGACGTAAAATTACTATCAAATGCTTGTATAAAACTCAAAAAAATGAAGTATAGAAATTATTAACCTTTAAAAATTCTCAGTCCATTCATATCTCATTTAAAAAAGAAGGAATTTGCAAGATATGAAAATATACCAATCCTAAAATTAGCAGAGTGTAGAGGGTTGAACTTCCTAAACCAATAAGTAAATCTTTCTTGAAATTTTTCTGTTTGTTTTCAAAAAATACATCGGTAGCCCCGATTTGCATCATGATGATGCCTAAGATATTTGATATCCAATATCCGATAATCGTAAAAGGAATGAATAAATCTGGCGAAATCCAGCTAACTAAATAACCGAAAAGATAAGCTATTGGTAAATTGAAAAATAAATCGTTCCACCAAGATAGAGGTGAAAGCATATAGCCAACACCTATGAATAAAAATCCCTTTATTTTTTGCAGCATCGGTTAATCAGTGAACAGTGAACAGTTATCAGTTATCAGTAGTTAGAATTAATATGACTTCTAAAAGTACTGCAAAAGCTTTTAAATTTAAACAGTTCAAATTTAAATAGCATTTGCCCAACTGTCACTTTACTACAGTTCATTCTGCAAAAGAGACGAAATTATAAATTAACTGATAACTGCTCACTGCTCACTGTTCACTGTTCACTGCTAACTGTTCACTGTTCACTGTTCACTCCTAACTGACTAATCAAATCTCGAACTTTTTTCTCTAATTCTCCGAGGGCTTCTTCGGGAGAAGTTTTGTCAATATCGTGAATTAGCCAATATTCAATATTATTAAGCCATTGAGGAAAACGTTCTTGCATTAAAGAACGATGTTCCGATTCATCAACGGCTATAACTAAATCAAACTGTTGAAAATCTTCAGTAATTGCAGATTTAGGAAAACGTTCTTCTGGTGTGATAGTAATTCCACGCTGTTTCAAAGCTACAACAGCATACCGAGAAATTGCACCAATATTATTAACACCACGTTCAAGTGCTAAACCACGAGAATCGGCTTCCCAACTCAAATTTTTCTGAGAAGCTAAATCGTTAAATAATTTTTCAGCAAAGCGACTGCGATAATAATTACCCGTACATAAAAACAGTACTTTTTTCATTTTAAATAAGAAATTAGAGATTAAATCATATGATGCCCAATCAATGGCAAAGTCTTGAAATTGCTAGCTACGAAAACTATTTCATTTTGTTTTAACCGCTGCGGACATCATATAATATATGCCCTAATTTCTTTGCTACATTTTCTTACCTTTGTGATGATAAATTGCTGCAAGATTGTTTTGAGCCATTTGCCATTCATCGGGATGTTCTTCGCGAGTATGAACTTGTAATGCGGCTTGGTAATGATGAATCGCTTTGTCAAGATTTTCTGTTCTATCTTCCTTGAGTCTATTGCTATAAGCAGTACCCAAGTTATTTTGGATCATTGCCCATTCGTAGGGATATGTTTCGCGGGTATGATGCTGTAATCCGTTTTGATAGCAGACAATTGCTTTTTCAATATTTTCGGCTTTTTGCCCGCTAACTCTATCGGCGTAAGCATTCCCCAAGTTATATTGAGTCGCTGCCCATTGTTCGGGATAATTGGAAGCAGTGAATACACAATTTACCACTTCATAACCAGCAATAGCGATTTCTAAATTGTTTGCACGCTGCCCTAAAGGAAATTCTTGAATCAAACTGCTGAAAATACCAATAGTGGCAGTAATATCTTCTGCTTCTTCAGTAGTTGACTCGGAAATTGCATCCATAGCCCAATTTCGCAAGAATTCGGCAAAAGTAGCATCAAGGAAATTTATATTCTTATGTAGTAATGGGTATACAGCTTCTGGATTACCTTCAGTCTCTTCGGTAATTAGCAATGCTTGTATGAGTAATTCACCTTGATTGTCTGCCTTAAAATCTGAAAGTGATAATCCTAAAGCTTCAGCTAGCTGATTTGCAATATTTATCAAGAATTCCGCAGCGTCTTCATTACCTTCTTCAGAAAGTCCTTGCGCTACCTCTATCATCGTCTGCACTAACCCGGCATCAATATATTCGGGTTCCGTATCTAAAGCTATTTCTTCTTCTTCGCCCGTCGCATTGGTAAGTAGCTGATTGATTATATTGAAATAAATTTGGAGACGCTTTTCATCCATCGGATTTAAAAATATTTTTTCACTGCTTTACTAGAAAACTATCCATAGGAATGTTTTTCAAGAGTGAATAAATACATTTAAGATAATGGGTAATGGGTAATTGGTAATTGGTAATTGGGCATGGGGCATTGGGCATTGGGCATTGGGCATGGGGCATGGGGCATGGGGCATGGGGAGAAGAATTAATTTCTCAACTCACTTTCCTTACTCATTTACTCCTTACTTATTACTCACTACTCCTTACTCCAACTGCATAAGTTAATTCGACTCACACCAATATAAACTTGTAGCAGAGCTTTTGGAATTATACCTGTGGATTACTCAGGGCAAAACCTACGAGGAAAGTCATTATATTTCTACAGTTGCGATCGCGGAATTATTTGAGTTATTTAGTCAAAGAAATAATCAAAATCAAAAAAATATAGAATGCGTGATTCTAAATGCTTGTTATTCTAAAGTGCAGGCAACTGCAATTTCGCAACATGTGAGTTACACGATTGGGATGAATAAAGCTATTGGAGATAAAGCAGCGATTGAATTTGCAGTGGGTTTTTATAGCGCTTTAGCTGCGAGAGAGTCAATTGATTTTGCTTACAAACTCGGATGTCACAGTATTGCAATGGCTGGGATTCCGGAAAAATTAACTCCCATACTCAAGGTGAAATGAAAGCATTAGCAGCAAAATTAATTTCAGATAAGGTTTGGGAGACGTAGCACTGCTACGTCTCTACATTTTATACCATTTCTTTATAAAGATGCGCCATATTTAGCCAACGTAGGTTGGCTTTGTATTGGTAGCTCCAGCCTTCCAGGCACAGAGCGATTCAGCGCAACCTCATACAGAATTGGTATTAGCAGTCAAATATAGCGCTTTTCGGTTGAGTAAAAAATTAGACCTCACTCCAACCTCGTGTACCCCTCTCCTTAATAAAGAGAGGGGTGCCGCAGGCGGGGTGAGGTTCAGTCTGTACCTACACCGCACAATTTAAAGCGCCAGCTTTTTTAGTAAACCGCATGTTTTCGCGATAATCTACTCGACAATCAATTACCGCAGGAACATCTTGGGCTAAAGCTTCTTTTAACATCGGAACGAAATCGGTAGCTGCTTCAACTCGATAACCTTTTAATCCCATACTTTCGGCAAATTTCACAAAGTCGGGATTACCAAACTTGATAAAAGATGCTTTACCTTCACCGAATTGATTTTCCTGTTTCCACTCGATTAAACCATAGCCACCATCATTAAAAATTAAAGTCACAAATGGCGTACCGACTCGCAATGCAGTCTCTAATTCCTGACAGTTCATCATAAAACCACCGTCACCACTTACCGCTACAACTTTACGGTTGGGATGAACCAGTTTCGCTGCTAAAGCTCCGGGAATTGCAATTCCCATTGCTGCAAAACCATTAGAAATTAAACAAGTATTGGGACTATGACAGTGGTAGTGACGGGCAATCCACATTTTATGCGCCCCTACATCGGATATTACAATGTCTTCAGGCCCCATCACCTGCCGCAAGTCGTAAATTAACTTTTGCGGCTTCATCGGAAATGCATCATCGTCAGCATAATTCTCGTAATCGGCGCGAATATTTTCTCTTAGTTTAATCGCGTAGGGTGCAGCTTTATCATGTCTATTTGCTACCTTCAAAATTTCATTTAAAGAATCAGTTATATCACCAACAACTTCTACCTCTGGAATATAGCTGCTGTCAATTTCCGCTAACTTTGAAGCAATATGAATAATCGGAATCTCACCGTTAGGGTTCCATTTTTTAGGAGAAAATTCAATTAAATCGTAACCAATTGCAATTACTAAATCAGTATTATCAAAACCACATATACTAAAGTCTCGTTGCTGCAATCCTACAGTCCATAAAGCTAAAGGATGAGTATAAGGAATTATCCCTTTACCCATAAAAGTATTGGCAACCGGAATATTTAACTCTGTGGCAAATTGAGTTACGGCATCGCTGGCTTTTGCACGAATTGCTCCGTTGCCAACTAAAATTATTGGATTTGTAGCTTGAGAAATTGCAGCGGCGGCAGCTCTTATGGTTGCAAAAGAAGCAAAGCTTTTTTCTACATTATCTTTACCTAAAGGCTTACCTTCTACCGGCATTGCGGCGATATTTTCTGGTAAATCTATATGTACCGCTCCCGGTTTTTCTCTCTGCGCTCTTTTAAAAGCTTTACGAACAATTTCCGGTGTAATACTTGGTCTGACAATTTGTTTGTTCCACTTAGTTACGGGAGCAAACATGGCTACCAAATCTAAATATTGATGGGATTCGATATGCATTCTATCAGTTCCCACCTGTCCGGTAATTGCCACTAAAGGGGCACCATCAAGGTTTGCATCTGCAACCCCAGTCATTAAATTAGTCGCACCAGGACCTAATGTTGAAAGACATACTCCTGCCTTTCCCGTCAAACGTCCGTAGACATCCGCCATAAAAGCCGCACCTTGCTCGTGACGGGTTGTAATAAACTGAATTGAAGATTTTTTCAAAGCCTCCAATACGTGTAAATTTTCTTCACCGGGGAGTCCAAAAACGTATTGCACCCCTTCATTTTCCAAACACTTCACTAGTAATTCTGCTGTATCCATTGTGATTCCCCTGCTTTAGTTAGTAGATAGTGGTTAGTGGATAGTAGATAGTGGATAGTGGATAGTGGATAGTAGTTAGTGGCTTTTACAACTAACAACTAACAACTAACAACTAACAACCAACAACTAACAACTAACAACTAACAAATTTATTTCACCCACACAGTTTTAACATTGACAAACTCATGTATGCCTTGAATGCTTAATTCTCTTCCATAGCCGGAAAGCTTTGTGCCACCGAAAGGCATTCTGGGATCGGATTTGACTAAACCATTGATAAATACAGCGCCTGCTTCGATTTCGGAAATTAACCGTTGCTGTTGAACTGTATCGCTCGTCCAAGCACTCGCACCCAAACCGAAGGGTGTATTATTAGCAAGTTGTATTGCTTCATCAATATCTTTAACTCGGAATAGCATCGCTACCGGGCCAAAAAATTCTTCTTTAGCCGTCGCAGAATCGGGAGAAATGTTAGTCAAAATTGTTGGTGGATAATAATTCCCTTTCATATTTAATAAAGGCTTTCCTCCCAACAATGCGGTTGCACCGCTATTAATACTTTTTTGTACTTGCTCGTCTAATTCCTTGAGAATATCGTGAGTAGCGAGAGGCCCGATATCAGTATCAATCTGCATGGGATCGCCAATTTTCAAGGCGTGAAATTTGTCCAACAGCAATTTTTCAAACTTGTCAGCAACAGCCTCCTCAACAATAAAGCGTTTCGCTGCTATACAAGATTGCCCGTTATTCAACATTCTTGCTGTAGTTCCAGTCACAGCCGCAGCTTCTAAGTCAGCACTTGCTAACACGATAAACGGGTCGCTTCCTCCTAATTCCAAGACAGTTTTTTTAATATGCTTACCAGCAGCAGCAGCTAATGAAGCTCCCGCTCCTTCACTTCCTGTCAAAGTGGCAGCCTTAACCCGCTCGTCGGCAATTATATCTGCTACCTTGTCCGAGCTTATCAATAAACTTTGAAAAACACCTTGGGGAAAACCCGCTCTGTGAATAATTTTTTCAATAGCTAAGGCGCACTGAGGTACGTTAGAAGCATGTTTGAGCAAGCCCACATTGCCAGCCATCAGTGCCGGAGCTGCAAACCGAAATACCTGCCAAAAAGGAAAATTCCACGGCATAACTGCCAGAACTATCCCTAAAGGTTGGTAACTGACATAACTATGACTGGCATCTGTTTCTATCGAAACATCCTTTAGAAATCCAGCAGCCTTATCTGCATAATAACGGCATACCAAAGCGCACTTACTCACTTCAGCCAGAGCGCTTTTATAAGGCTTGCCCATTTCCAAAGTCATTATTTGAGCAAAATCTGCCTTATCTTGTTCCAAAATATCAGCAGCTTTGTACATCCACTCAGAACGCTGCCCAAAACTAGTTTTGCGGTAATCCCCAAAAGCTTTATGAGCCAAAGATACAGCATCCTTGACTTGGGTATCGTTCAAAGACTCAAAAGAATTGAGAGTTTCCCCAGTTGTGGGATTTATCGTGGCGATCGCCATAACTCACCTCTCGAAATAATTGGTTGAAGCCATACCATCCTAGATTTGAGACTTGGGATTGTCACGGACTCATAGCACAAAGTCATCATGAAATCTATTCGTCACAATTTGGTATGACTTAATAGTTTTACACGCTAAAAGTGAAAACCACTACTTAAATTTTAGTTATACCTTTTATGAAAAGTTGCCAAATATTAAAGATTCTCAATGAAAAGAATCTCAAATGAAGATTTACAAGAGGAAGTTGAAGAAGTTGAGGGGAAAATTAATTTCGATGGGCTGTATTTCTATTTTGCTCATTTCACCGCAATGCACCAATATCAAAACCGTATTTATACAGAGTTGTTTTGATTTGGTTACTTGAGTTGATATATTCAACCTTTAGCTATTGCAGTTCCCAAGATGACTTTTTGTTACTTCCATCTATAAAACCTATAGCAATGGTTTTATAGATGGAAGCGGGATTTATAAATGCCTCGGACTTTAAACCCTTATGTTATAGCCATTAGAGTGAATCCGATATTTTCCAAGCTATTGATGCGATCGCCAATTCAGCGCGCAAAAAACTGAACCGCAAACATCGTTAGAAAGAATAGCGAGAATAGGTATATTAAACTGTCTGTATTTAAAAGCATGGTATGTGTTCCCTAAAAACTTTTATCAATAGACTGAGTATATTCACATAAATGTTCCGGGAAAAAATATCAGTATAAACACTATGTTAAATAGTTCGAGCTATATCTATTAGCAATAGTAATGAATGTAATTGTCAATACTTCCGGGTATAGAAATTAGTTCTGAATACGGTTAACATAGAGAGTACTATTTGACATCCTCAACTATCCGGATTTATGCAAATTATTCATTTTTATTTAAGATTTAATAGAAATAATATTAATTACGTAAATTTGCGCTGCCTTTAAAATAAGTTTTCAATAAAAAACTCTAGCTCTGACGATTACTTTACGCAATGAATAAAATGACAAATCCCCATGCCCAATGCCCAATCCCCCATGCCCAATCCCCAATATTTAATATCGTCTACGGTTGTGATAAACCTTAACCAAGCGATTGATACCTTTGAAGCGATATTTGCCCATTAACTCAAATCTATTGGGCTTAGAAAGCATTTTATGAGTTTCTTCGCTAACTACGCATTCCCCTGGGTGACAAATTCCTTCCATGCGCGCTGCTAAATTAATAGTTGCTCCTAAAGCTGTATATTCCACTCTTTGAGAACTACCTACATCTCCCACAACAGCTTTACCGCTATTAATTGCAATTCTCAACTCTAATGGTTCTTGCCAAAAATGATTAAAATTCAATTTTTCTAAACGAGCTAACATTCTCATCGCTGCAACCACAGCCCTATCTGCATGGTCTTTCTGCGGTTCGGGTGCGCCAAAAAACGCCATGATGCAGTCGCCGATATATTTATCCAAAGTACCGCCACAAGCAAATACCTCCTGTAGCATTTCCTCAAATAATTTATTTAGTAATTCCGCAATTTCCGTAGGAGTAAACCTTTCAGACATTGCCGTAAACCCCACTACATCGGCGAATAAAATGCTAATTTCGCTTTCTTGGGGTGGTAAACGTCCGTCAGGTAAAGCTCCCAATGCTATCAACTGCTGTACAACCGCTGGTGAGTGATAGCGCTCCAATCTTTGCCTGATTACTTCTTCATTCTTGAGCTTTTCTACTAACAGCCAACGCTGAACGCTTGAAGAAACAAGATTTCCTAAAGTTGAAAAAAAGCTCAAATCTTCCGAACCTTCTTTAATCCAATGGTAGGAAGAAAAACTGGCATCAGCATAAAGTACCCCCACAACTTTGTTTTCGTCCCATAATGGTACTGCCATTGCGCTGCGAATACCCTTGAGAAAAACGCTGTGTTCTTCGGCAAATCGTTCGTCTTGATGGGTATCGGCTGACTGAATTGCAACTTTTTCTCCAAAGACTTGCTGGCATATACTCTGGCTAATCCAACTATCATCACCCATTAATTGCTGCTTATTGTTAACATCCCGACTCGCAGCATTTATCAAAACTAATTTACCGCAGTTGCTAACATCAATTAATAATCCCAGACGGTCAATGCTATTAAGATAACGGAATACAACTTGTTGTACCTGCGAGAAAATTTCTTCAATAGAAGTAGCTCCCGAAAGGTTTTTGGCTATATCTACCAAATCTTTAAGACGAGCAATAGTTCTATCTTTCTTGTTAGTATTGTCTTCTTGACTATCGGCACCTATCCACTCCTCTTGTAATTGCTTGACATTACGAAGTATTGTTCTGCCTTCAGAAAAAGCTGTATAACTGCTTTGGGGTGGTGGCTCGGGAGGAATAGTCAAAAGCACCACAAGAGAAATATCTCCAACCCAAATGACATCCCCATGAGAAATTGAGGTAGGCTTAATTACAGCTTGTTCGTTTAATATTGTGCCGTTTTTACTGCCTAAATCTTCGACCATCCACAAACCATTTTCCCCTTTAGCAAAACGCGCGTGACTGCGAGAAATTCCGCTAAAAGGTAAACATAGGTTACATTCTGGCAACCTACCAACAACATAAATATCTTGATCCACCGTCACCGTTTTTTGGGTATTTCCCCGTTGGAGACGTAGTTTCAACTCGGTCATTCGATTTCGGATTTATTATTTTAGGTTTTAAATGGGTTGGCGAATGCAGAAAACTCTGCTGCCGTCAACTGTTAGATATGTGATACAAAGATACTATAGGTTTTTCAAAGCAATACATTTCATTTATGACACTGCAAACGGCACTCCGACAACTATAACTCTTGTCCGAGAAACGATTAATCCCAGAGAAGCTCTCAAAAACCTGGAAGCCTAGTACAGTAAGGCGTAAATTTGGCAACCATTGCTAACGATTAAAATCCTCATCCTATAAGACTTCTTACTTCTTACTTTTTACTTTTTACTTCCGCGCAGCGGTACTAGTCTTTTAACCCTCCCCCAAATCAACCTAACAATAAGCTCTGTAGCCTATTTTATTCAAATAAATGGAAATACTTCACTAATTCTTTATATAAGTGGGGTTGCATTTGCTGTATATGAAGAAAGAATACAAAAGGAAGCGCTACAATCGAACTTAATTATTTGTGATGGTGTAGTTATTTAGAAAAACCCATTATTTAGCAATATAACTAATATTTGAGTCATTCAACATCAAAGTCTATCGATTATTTTATCTAACCGACGTATTTATGAATCAAGATAATTCAACTGAATCTAAAACTTCTATTTTTTTAATTTTAGTAATTACAAGCGTAGTAATAGTCTTAGCTGCGACATTATATCCGTTTAATTTCGCATTACCAGATAGTATCTCTAAACGAGAATTAGTGAATAGTTTTGACAACAACAGTTTCTTTAATGACCAGGTAAACAACGTTTTACTATTTTTGCCTTTAGGATTTGGCTTGACGGGTTTGCTGCAAAAGCGAAAAGTGAAATTGGTTTGGCAGATTTTCGCAGCATTTTTAGCCAGTGCCGCTTTATCTTCAACGGTAGAATTGCTGCAAATTCTGGTACCTTCAAGAACTCCAACACCCGCCGATATTTTTAACAATAGCTTTGGTGGCTTTTTCGGGCTGATTTGCTTTTATATTTGGAATTCTCGAAGCTTTAAAGCAATATTGCATAGAATAGAAACTAGTAGAGCAAGTAATTCCATCAGCAAGATTACCTTGTTCTTTACTGGTTATGTGATTCTGACATTTTTAATTACAATTCCCTGGCAAGCTACAACCAATTTAACTGGCTGGAATCCGAGTTTTCCATTGATCGTCGGTAACGAAAGAACAGCTAATAGAGGATGGGAAGGTTATATATCGCAACTCAATATTGCTAATCAAGCTTTTTCTCAGAATCAAGTAAAGCAATTATTTTTGCCGAATAATAGTTTTGAAAATCTCGGAAATTCTGCAATTGCTGCTTATGAGTTTAAAGGAAAAGCACCATATCAAGACAGAATTGGAAAACAACCAGACTTATTATGGAATGGAGAATCAGCAATCCAAAATGAACAAGGAGTATTTATAAGTTCAAATAACTGGCTAAAAACAGCAACACCAGTCACATCTTTAAGCAAAAGTATAAGTAAAGCTTCCGAATTTACTATTAGCACTACTCTGGCTACTAATAAAACAGAACAAGTTGGTCCAGCAAGAATTATTTCTCTTTCTAATGATTCTTTTCGTCGTAACTTTACCTTGGGACAACAAGGAAGTGATTTAGTCTTTAGGCTGAGAACTCCCCTCACAGGAGCCAACGCTTCCGATGTAAAATTAGAAGTGCCCGGTGTATTTAGCGATATCCAACCACATCAAATAGTTATCACTTATTCCAAATCATCGTTAATAATTTATGTAGACAGCATTAGCAACATTCATACCTTAAACTTACTCGACTTAATACCCAAAGAAAAAAGATTTTTCTATTACGGAATCACATTTATTCCGTTTGGCTTATGTTTAGCGTTGCTTACAACATTAGCCAAAAGAAAAATCAACTTTTACCGTTTGTTACTTCCCGCCGGGATATTATTACCTTCTTTGATATTAGAAGGAATTCTCGTACAAGAAAGCGGTAAAAGTATCAGCCCCAAAAATATCTTTTTGGGAATCTTATTTACAGCCGGTACAATGTTTATATTGAAAGCGAGAACGGGAACAGTTATCAGTGAACAGTCAACAGTCAACAGTCAACAGTGAACAGTTATCAATTTTCATATTGAGAATGTAGTTAATCAACTAATTACAACTTGTTCCTTGTCTCCGGCAAAGAATACGTTAGTGGAAGGCTCTGCCTTCTGTCGTCAAACGAGGCAGAGCCTCTTGAGAATGCATTTCAAGCCAGAGATTTGGAACGAGCTACTGTTCACTGATAACTATTAACTGTCAATTGATTCCGGTACTTCTAAAGGAAATTGACCCAGATTTCCTTTGCGATAGTCGGTTAAAATAGTTCTTGCACTACGCTCTACATCACCTTGATATTTATGTTCGGCTAAAGCGAATAAATATTCTTCTCCGGTATAGGATGTTGATTCGAGCTTGTAGCGCAATAAAAATGGATTTTCAGGCAATATTTGGGGAGCAGTTTCCTGCATTTCTCCCACTATATCTACGAATGCTGCTGCTACTTTTTGATTATCATAGGATGCTTCTCCAATATCGTCGCAAATTGCTAATTTTAATGCTGCTTCCTGATTTTCTAACTTGAGCGGAATTACACCGGGAGCATCTAATAAGTTTAATTCCTTGGAGATTCTTACCCATCTCAAAGAACGAGTTACACCAGGGCGAGCCGCACTTTGTACAACACGTTTACCCAATAGCCGGTTGATCAAAGCTGATTTTCCCACATTAGGGAAACCAATTACTACAGCACGTATAGGACGAGGTAACATTTCCCTTTCTTTACGTCTTTCGTTAACTTGACTGCCAGCAGATTGTGCTGCTTTAGCAACTCCATTTACCCCTTTTCCTTGTTTGGCATTGGTAAAAATGGGAACTTCGTTATTAGCTCTAAAATAATCCGTCCATAATTCCCTGGCTTCAGATGAAATCATATCTAACCGATTGATTATTAATAACCTGGCTTTATCTCCTATCCACTCAGATACTTGGGGATGGTGAGTTGATGAGGGAATCCGAGCATCTCGAACTTCTAAAACAACATCAACTAATTTCAGTTGTTCTTTTAGCTGTCTTTCGGCTTTAGCTATATGACCGGGATACCATTGAATTATATTTAATTTATAGTTATGGGTTATAGACATAAGAATAGGTCAGTAGGGAGTATGGAATAGGGAATAGGAATTAAATTTAAGTATATAGCTTTGTATATATGTTTAAAATTTACCTTTTGCATGGGACTGATGCAAAATAATGCGATTGCCATCAATGTCATAAGCATAAACTTCTCTACCGTGAGAGGCGTTGGTAATTTCGTGAAAGGGAGGATGACCTAAGTTTTCGAGATGAGACATAACAGTTTCTAAATCTTTAACCTCCAAACACAAACTCATGCTGCTTTTAAAAGAATCATTGAACTCAGCCAGGTGAGATTCTTTTGGTTTAAAAATAGCTATTTTTAATCCTGAAAGCTGAAATTGAGCGTAGACATTTGGAATATAATTACTCGGTTTTTGACTGAGGAATTGAATGTAGAAATCTACCAGTTCTGAAAAGTTATTTGTAGCAATAGTGACAAAAGCTTCCGCGCATTGAAAAAACATATATAAAAAAATTGATACTAAAAAAATGAGTCATCTTTAAAACAGCAGAATCAATTTGATAAATCATTTGAAGCTGTGTTCGGTTGGTGTTGAATATCTTTCTCTAAATTACCTAGCTAACAAGTATTTGCAGCAAATTTTAATAATATCCCATCCGGGTCGAAAAATAAAACTAAGAAGTGAAGGTGTTTGCATCAGGTTCTGCAACATAATCAGAAGGAGCATCGGCATGGTGTCAAATTAGCGTTCTTTAAATGCCTTTATTAGTAAGTTTTTCTCTATATTCTGCAACTTTTTCCAAAGGTACTTTAAATCATCTAACATTTAAAGTACCGCAAGCGGTAGCAATATGACTCGTAATTCAAGCGTCTGGATTTACAGAAGCTATTTTTGATGAAGCTTTATCTCCTGAGTTTGAAAATATTTCATCATTTTACAATAGAGTTTAGACAACTAAATTATGTGTCAAATAATTGTTGATAGTCTATATCTTCTTATAAAAATTAATTATTTATATTTTTGCACAAATCTGAAGTAAATACTTATCAACGATACGAATATGTAAGCTAATGGCATAATATGCTTTTATGAATTACAATTTTTAAAGTTTAAAATACAGAATTATACTCTGTAAAAAATGACTTCTATAAAAGATATTAATGAGCCAAAAAGGGTTGATTATCAATATCAGGTTGGCGGCAGTTTAGAAAACGATGCTGATTGTTATGTAGTGCGTCAGGCTGATGAAGAACTATATCAAGCTTTGAAGTCTGGAGAGTTTTGCTATGTGTTTAACTCTCGGCAAATGGGTAAATCGTCAATTATGGTACGCAGCAGCCATAAATTAAGCAAAGAAGGATATCAATGTACTACAGTTGATATGAGTTGCGTTGGTAGCGAACAAGTTACTCATGCTCAATGGTACAAAGGAGTTGTTGCTGAATTATGGCGAGGATTTCATTTATTCGGTAAATTTAACTTAAAATCTTGGTGGCGTGAAGAGGAAGATATTTCCGTACTTCAGCGTTTAAGCCATTTTATTGAAGATGTACTTTTAGTACAGTTTCCCGAAGATAAAATAATTATCTTTATTGATGAAATTGATAGTATTCTGAGTTTAGATTTTCCTGTAGATGATTTATTTGCTTTAATTCGTTTCTGCTATAACCAAAGAGCTTTAAATCCAGAATATCATCGCCTTACTTTTGCTATTTTTGGAGTAGCTACACCAAGCGATTTAATTGCTGATAAAAATCGGACTCCATTCAATGTTGGTAAATTAATAAATCTTGGGGGATTCACTTTAGATAGAGCGCAACCTTTGCTAAAGGGATTAGAAGATAAAGTAAGTCATTCGGAAGCAATTTTAGAACAAATATTAGCTTGGACTAACGGACAGCCATTTTTAACTCAGAAGCTTTGTAAAATGGTGAGGAATGCGGAATGGATAATTGCAAAGTCAGAAAACGAAGCTCGAATTGAAGTTGATAAATTAGTTGTAACGCAAATTATTCATAATTGGGAGTCACAAGACGAACCCGAACATTTGAAAACTATAAGAGATAGAATTCTCCAGCAGCAGAAAGCGGGAAGATTGCTTGGTATATATCAGCAAATTTTACAAGGTATAGAAGTTGAAGCGGATATTAGCAGAGAACAAATGGAATTGTTTTTATCTGGTTTAATTATCAAAGAGAATAATCTCCTCAAAATTAAAAATCCAATTTATGCAGAAGTATTTGATTTAAAATGGGTATCGCTAAAATTAAGTCAATTACGTCCTTACTCTCAAGCTTTTGATGCTTGGGTTGCTTCAAATAAAACAGATACTTCGCGATTGTTACGAGGACAAGCTTTAAAAGATGCTAAAAAATGGACTTTGGGCAAAAGTTTAAGCGATTTAGATTATCTTTATTTAACAGCTTCTCAAGAATTGGACAATTACGAAACTCAGGAGCATTTAGAAGCACAAAGACTTAAAGCTGTTGAAGCAAGACTAAAAGCAGAAGAAAAAAGTGCAGCACGTTTAAATTCCTTATTATTTTCTGTTAGCAGCGCTTTGATTGCTGTTAGTACTTTAGCGGCTATTACATTTGTTGCTTATCGACAAGCAAAATTGAATGAAATTAAAGCAATAGCTACTTCGTCTAGAGCATTATTTGTTTTAGAAAAACGTTTGGATGCATTAGTTCAAGGTTTAAAGGCAAATAAAAAAGCTAAACAGTTTGGCAAAACTGATTCTCAAACTGCAAGAGAAGTTACAACTGCTTTAAGGAAAGCTATTTTTACAGCAATTGAATATAATCGGATTACTGGAATTGATTCTCAGATTTGGGGTGTAGATTTTAGTCCCGACGGTAAAATAATTGCTACAGCTAATAGAGATAATACAGTTACACTTTGGACTCGTAGCGGTACAAAAAGTAAACCTTTAACCGGTCATAAAAATGCTTTAAGAACTGTTGCTTTTAGTCCGAACGGTAAATTTATTGCTTCTGCTGGTAGAGATAAGGTAATTAAAATATGGAATCGCAAAGGTGATTTATTAAAAACTTTGGAAGGTCATCAAAATGTAGTTTCATCAGTTGCTTGGAGTCCAGATAGTAAGACTATTGCTTCTGGCAGCTACGACAAGACTGTGAAAGTTTGGGATGTTGATGATGGTAAATTTAAACTAAGTTTTAAAGCTCACCAAAATTTAATTAATGCAGTTAATTTTAGTCCAGATGGAAAAAACATTGCTTCTGCTAGCGTTGATAGAACTATTAAACTATGGGATACAGAAGGAAAGTTAATTCGCATTTATAAAGGTCATATAGATGAAATTTATTCAATAGATTTTAGCCCTGACGGTAAAAAGCTTGTTTCTGGAAGTATGGATAATACCGTAAAACTGTGGCAAGTAGAAGATGGAAAGTTAATTGATACGTTTAGAAATCATGTTTCTGGAATTTGGAAAGTAAGATTTAGTCCAGATGGTAAAACCATTGCTTCTGCAAGTTGGGATAATACGATTAAATTATGGAATATTAATGGTATTTTATTAGAAACTTTGAAAGGGCATAATGGTAGAGTCCGTGGGTTAGCTTGGAATCCCAACGGTCAAACTCTTGCTTCGACTAGTGAAGATAAAACTATCAGATTTTGGAATTTAAATAATACTTTAGTTAAAACTCTTTACGGTCATAAAAATGGGATAATCAAAGTTGCTATCAGTCCTGATGGTCAAACTATTGCTTCAGTTAGTGATGATAGCACGATAAAACTATGGAATCGGAATGGTGAACTACTTCAAAGCATTCTAAGCAACTCTAGAGGATTTCTTGATGTTAATTTTAGTCCGGATAATAAAATCATTGCTTCAGCAGGTAATGATAATGTAATTAAACTATGGACTACTGAAGGTAAAGAATTAAGTGTTTTAAAAGGACATAACGCTCCAGTTTGGTCGGTAGTTTTTAGTCCTGATGGTAAAATAATTATTTCCGGAAGTGAAGATGGAACAGTTAAATTGTGGAATATTGACGGTACTTTAATAGATACTATAAATACAGGTCAAGGAATTATTCGAGCAGTTGCATTTAGTCCCGACGGCAAGATGATTGCTTCGGGTGGTAAAAATAAAACTATTAAATTATGGAATCTTCAAGGTAAACCTTTAAATACTTTGAAAGGTCATTTCGATACTGTCGTAGCAATTGCATTTAGTCCCGACGGCAAGATGATTGCTTCTGCTAGTTTGGATAAAAATATTAAGCTGTGGAAGCGAAATGGTGAATTGATTAGTACTTTGCGAGGGCATAATACTGATACTAGAGGAGTGGCATTTATTTCTACTCCAATTAATTCTTCCAATATTAATAAACAGAATTCTAAGAATTACATAATTGCTTCGGCTAGTGGTGACAGTACAATTAAATTATGGAATACAAATGGCAAGTTAATTACAGCTTTGCAAGGACATAAAGGTGCTGTTTGGGATGTCGAATTTACTCCAGACGGAAAAACTCTTGTTTCTGGCAGCGAAGACAAAACTTTGATGTTGTGGAATTTAGAAAAAGTTATTGATAGCGACAAAGTCCTTACTTACGCTTGCGATTTAGTCCGAGATTATTTACAAAACAGTGCAGACGTAGATTCTGTAGATAGGAATTTATGCGATTAATGGTAATTGGGCATTGGTAATTGGTAATTGGTAGTAGGTAATGCAATACTGCTCGGTTAAGAGGAGATCCTCCCTAACCCTCCTTGAAAAGGAGGGAATAAAAGCCCCCTTTTTTAAGCGGGTTGGGGGATCTCAAAACGAGTTTAATGGCTTAACCGAGTAGTAGTAACAACATGCGAACACCAAAAATAGTTTCTTCTTCGTTCCCTTGTCTCCCCATCTTATTTTCCCATGCCCAATTACCCATTCCCTTTTTATAAAATAGTTTTTGTCAAACTTTCGGTATAGGCTCAATTTCGCTAGCATAGCTACCATCAAAGACGAAAGTCTATTAGGACAACATTATTATGACTAGCATCTCATCTGTACCCGATTTCATCGAATCACTATTAGGTAATGAAGCTAAAGATTTACTTACCCACAAAGCAAAAGTATCAAAAGATATGCTTCACCTACCGGGAAGCGATTTTGTAGATAGAATTTGGGCATCGAGCGACAGAAACCCCCATGTATTGCGTAGTTTGCAATCTTTGTACTCTACGGGAAGACTTGCGAATACTGGTTATTTATCGATTTTACCTGTAGACCAAGGTATTGAACATTCTGCGGGTGCTTCCTTTGCTCCGAATCCGATGTATTTCGACCCCGAAAATATTGTTAAGTTGGGAATTGAAGGTGGTTGTAATGCGGTGGCTTCAACTTTAGGAGTATTAGGAATTGTTTCCCGTAAATATGCTCATAAAATTCCTTTTATAGTTAAAATTAACCATAACGAATTACTCAACGTTCCCAACGATTACGATCAGGTAATGTTTGGTGATGTCGAACAAGCTTGGAATTTAGGTGCTGTTGCCGTCGGTGCAACAATTTACTTCGGCTCGGAAAACTCCACCCGACAAATTCAAGAAGTAAGTAGAGCCTTCAAACGCGCTCACGAGCTAGGAATGGCTACTATCTTATGGTGCTATCTCCGTAACAACGCCTTCAAGCAAGACAAAGATTATCATCTATCTGCCGATTTATCTTCTCAAGCCAACCACTTGGGCGTGACAATCGAAGCCGATATTATCAAGCAAAAAATGCCCGAAAACAATAACGGATACGGTGCAGTTGCTAAGGCGATCGGTAAAAGTTACGGAAAAACTCACGAGAAAGTTTATAGCGAATTATCCACAGATCACCCCATCGATTTAACTCGCTATCAAGTATTAAACTGCTACTGCGGGCGGGCAGGGTTAATCAACTCCGGTGGTGCCGCCGGTGAAAACGACTTTGCAGCAGCAGTACGTACAGCAATTATCAACAAGCGGGCTGGGGGAACCGGCTTAATTTCTGGACGTAAAGCATTCCAACGTCCTTTTGAAGATGGTGTTAAGTTGTTCCACATGATTCAGGATGTTTACTTGTCTGAAGATGTGACAATTGCTTAAATAGTAAGTAAGGGCGTGTTTTCAAAGTACTCCTCACCCTATAAGGGTGAGGCTATATTTACAAAGTCCGCCTGCGCGGACTAGAAAAATCTGGGTTTTCTAGCCCTTTGGGGGCTTTGTAGATGTAACTCCAGGCTTTAGCCTGAGAGCGGTTGGGGTTTGAAAACACGCCTTAGGGCAATTCATACTTTTAATCAGCAACGCCTATTTATTGCTTCACTAACTCCCTTCAAATCAACAAAGCAAAATTCTTCAGCTTCTATCAGATATACGGGATATTCTTCAAAACTCACCGACTTTATTATTTGATATTTCTTCATGCTTTCAGGAATCAACTGAAAATAATTCTCTGTATTTTGTTTGCTCCGAAAATCCCAGATATCCACTTTCTATCTTCTTTAATGGCTTCAATGTAATTTATTTTTCTAAATTAAAATTTGTTTTCGTTTTAATTCTATTTATAAAAATACTTATTTCGATAGTTGTATAATCATTTTCCTAAATAGGCTAAAGTCAATAAATCAAATTAATTAATCAAAATCAAAAATAGTTGTCAATCTTGATACATAAGCACGTATACTAGGCACGGCACTATAAAATGCCAAATACGTCAATCATCCTGCCGCGATAATTTTGCTTCATTGAATGCAACAAATTAACGCGCAATAAATCAAACTCTTATAGAGTAAGCAGACATACCTGTAGACTAATGACGAATCAGTTTCCCAATCGAAGTTTACAAGTTCGCGTAAGACTAGTTAACTTATTCAAAAAATACAGACGGCTGTTAAAGCGCTGTCTTCCACTTGTATTTGCAATATCATTTTCTACGGTATTGCTGCTTGACAATTTGCAGTCTACAGCCCAACTCCCTCCTCCGGCGACTATTATCCAACCGGAAATATTCCAGCCCCGACAACTACCTCGTCAGGAAATTCGGGGAGTATGGATGAGTACTAATGATTTCAATGTTCTCAAAACTCGCTCTGGAGCAAAAGATGCTATAACTCAGTTGCGAAGATTAAATTTCAACACTATTTATCCTGTTGTTTGGAATTCTGGTTATACTAAGTTTCCTAGTATTACAGCCAAACGTGCTGGCATTCCTTTTTTCTTTAAAGGTGCTGATGGACAGGATATTCTTGCTGATTTGATTAGTCAATCCCATCGTCAGGGTTTATTGGTACTTCCCTGGTTTGAATTTGGTTTTATGACTCCTGAAACCTCGGAATTAGCCTTGAATCATCCTGAATGGTTGACTCAAAAACGCGACGGAAGCCGAACTTCTAATAGTGCGGCAGGGGAAGTTGCATGGTTAAATCCTTTTCATCCTCAAGTACAGCAGTTTATCCAAAATCTGGTTCTCGAAGTAGTTAGTAGATATGATGTCGATGGCATTCAATTTGATGACCACATGAGTCTACCTCGGGACTTCGGTTATGACAAATATACCGTTGCCTTGTACACTCAAGAAACCGAAAACCCACCGCCAGCAAATCCCGCAGATGAAGCATGGGTAAAGTGGCGTGCGGATAAAATTACAGCTTTTATGGCACAACTTAATCAAGCGGTAAAAGCCAGAAAACCTTATGTAATTTTTTCTGTTTCTCCCAATTACTACAACCACGCTTATAAATTACAGTTGCAAGATTGGCTCAACTGGGTGCGTTTAAGTATTGTAGATGAATTGGTGATGCAAGTTTACCGTAATGATTTAGCTAGTTTTACTCGCAAAATTAACCTTCCAGAAATTATTGAAACTAAGCGATATATACCTACTGGTATCGGTATTATGGCGGGTTTGCGAAATCGTCCAGTTTCAATGCGGCAAATTAAATCTCAAGTACGAGCAGCACAACAACGCGGTTTGGGTGTAACTTTCTTTTATTACGAAAGTCTCTGGAATTATGCTCAAGAAAGTGTAGAATTACGGCAATCTGGATTTAAGTCTTTATTTCCACGTTTTGCTCGTCGTTCAAGAATTTGATGAAAAAATAAGCAGATAATAAGGTAGAAAACAATTTGCGACTATAAAATAAACCCGGTTTTTGTACAAACCGGGTTTCTCAATCTAATTTAGAAAGAATTTCGGATTTTACACAATGCTAATTCTTTTCTTCTTGAAATAATTCCATCAAGCCAACTGTGCCAACGAAAAAAGTATATATACCATATTTATACCAAATTTTATCTTTAGAACCTGCTTTAAAAGCTGCTATGATTGCCTCAAACAAATGTGCTGCAACAGCAACACGTTCAATCCAAAAAATCGGTTTAATATTTGATGGTATTTGAAGTTGATGTGTTATCGCATAAATATTCCATATTTCTAACCCCATAGCACCTATCATCAGAACTGTAGACAATATTTTGATAGCGAATAAGTTGTTCTTCATGAGCTTTAATAAATACGAATATATTTTGCTTGATAAAAATTAAGTCAGTAAAGATTGTAGTCTATAAAATAACTTAAAAACCCGGCTTCTTAAAGAAACCGGGCTTTTAATCACTTTAAGCAATTACAATTCATACAGAATTATTACTACTTGATCGCAACTTTTGCTTTCTCTTCGCTGCTGCTAGCTTCATAAGCTTTCTCCAATCGCATAATCTGCTTTGCTTGCATTGATAATGCAGTTTTATCAAGCCAGTTTGCTATTAATGCATCGGTTGAAAACAAACCCGCACCATTGATGGTAAAGAATAGGAAGCAAGCTGCGTAAATCGCTGATAATTCCAAGTAGGAAATATTGAAGCCTGCAACCAACACGTGATGGTACATTGCAACGCACATTGTTGAGAATAAACCGAAAGCTGCCGGACGAGTCAATAAACCAAGTATCAATAATGGGGCACCAAATAACTCGGTAAAAGCTGCCACATAGCTAAAGAATATCGGGAAAGGCAAACCGATAACCTTTACGTAAGCTTCTGCAAAGCTTTCAATATTACCCAATTTATCCAAACCGTTGTGAATCATCATGATACCAACTACGGCTCTTAGAACAGCCCAACCTGTTTGCGAAAATAAATTAGGGCTGGTATTAGGTTTGAAAATGTTTGTTATTAGTGCGGTATTAGTCATATCTCAATTATCTATGCAGGCAAATCGATCGTATTTATATTAATTAACTTAACAAAATAGTTAAGAAATGTAAATATATAATTTTATTTATTAATTTTTCTGAGAAAATCTCTGTAATGCAGTCAGAAAATAGTTCATTAATCTTGTAATTGCGGCTTTATAGAGACTTATGCAATTTCGATGAATATGAAAGTATATGAATTTTAATTAAGCCGAAATTTTATCGCCGTTGCTTTTTGTTCAGACATTGCTATCAATCTGCAAATATGCATCATGCGATCGCGTTATTTTTGAAATCCTTACATGGAGCATAATTATGCCGCTATCCTTCATCGTAACTTGAAGTAATATCACTGAGATAAAATATTATTTTGCTGTATAAAATACAAAAAGTATCGAGCATAAGTAGGGAATGCGCTACCACAAATAAATCTCTTTACATCAATAGATATAAATACTTGTGGTATGAATAGCAAATTGTTTTATGTAAAAGCGCAGTTGGCGAAAGTTTATATTAAAGATGCGTTTCTAAAAAAAATTCTGCCTTTTTTGTTTCTGTCATCGATAATTTTCTGCTTACTTCTAAATAGTTTGGCTCCGGCAATAGCACAACAACCCCGTGATGAAATTCGTGGCGTTTGGATGACTAGTAATGATTTCAATATTCTTAAGTCGCGTGCAAAAGTTAATGATGCTGTAGGTTTATTGCGACGCATGAATTTTAATACTATTTATCCCGTAGTGTGGAATTCTGGTTATACAAAGTACCCGTCTAATGCCGCACGAAGAGCCGGGATTCCTTTTTTTTACAGAGGTGAGGAAGGGCACGATATTTTAGCAGACTTAATTTCTCAAGCACACCGACAACATCTGATAGTAATTCCTTGGTTTGAATTCGGTTTTATGATTCCTCAAAGTTCGGAATTAGCCTTGAATCATCCTGATTGGTTAACCCAAAAACAGGATGGAAGCCAAACCACGATTGGGGTTGCAGGTGAAAATGCTTGGTTAAATCCATTTCATCCCCAGGTTCAAAAATTTATTTCCGAATTGGTAACTGAAGTAATTACCCAATATGATGCAGATGGAATTCAGTTTGATGACCATATGAGCTTACCCCGCGAGTTCGGTTATGACAAATATACCGTTGCTTTGTACCGGCAAGAAACTGGTAACAATCCCCCTAAAAATGCTGATGATACAGACTGGATACGCTGGAGAGCGGATAAAATTAGCGAATTTATGATCGAACTCAATCATGCTGTAAAAGCCATAAAATCAGATGCGGTTTTCTCTGTTTCTCCAAATTATTATGATTTCGCTTACAAACTGCACTTGCAAGATTGGCTTAAATGGGTGAGAGAAGATATTGTAGATGAGCTAATCGTGCAAATTTACCGTAATGATTTGCAGTCATTCGTTGCTACAATTAACCGCGAAGAAATGCAAGAAACGCAAAAGAAGATTCCAACAGCAGTAGGAATTATGGCAGGATTGCGAAACAAGCCGGTTTCCATGCAACAAATTCAATCTCAAGTTAGAGCATCTCGTCAACATGGTTTGGGTGTATCTTTCTTTTATTATGAAAGCTTATGGAATCGCACCCAAGAATCGAAACAGTACAGAAAAGCGGGGTTTCAAGCTATGTTTCCCGCGCCTGCTTTTCGCTCTGCGATGAGGTAATGTTGACGAGTAAGAATGGTGAGGGCACAGAGGTGGGAGAATAAATTTTTATATTTTCCATGCGCCGCTCAGAAGAATGAAATGCACTACTATTCTTTTTGATTAATTCCAACGTAATGTAGAGATGTAGCACTGCTACGTCTCCCAACGTTATGCAGAAAATCAACCATTCAAAATTAATGAAATGCACTACTCAACAATATTAATTCTGAGATGTGCGGCAATCATATTTTTAAACCATCTATTTTTATACCAGCAATAAATTTTAGCTATAGATAAATGCTGACTTTTTTCAATAACTTATTTACAATAATTAATATAATTTTGCATGTAATTAAAACATTCTCTGCAATCCCCGCACTGTCTATTATTGAGATAATATTAGTGGTTGCTCGCTATTTAATTAAATGTTGTTTCATGTTTTTGACTAATTATATAGACTACAATCGGCGCTAAAGTTAGAGGTATAAGGTTTTATCAATTTTGACCTCAAGTTTTTCTGAAGCATTTTAATTATGCAATCAAATGCCGAACCTATTGATTTACCTCCTTTAACTCGGTTTATAAATACTTCTCCTGCAATAGTTACCCCAGAGACTTTGGTGATTGATGCGATTGCTTTAATGAGAATTCCGGTTCAAAATATCAATCAAAACTTGAATGCACCTAATATTTCTCAAATAACAGTTACAGCAAACAATCAACAAACTGATTGCGTACTAGTCTGTGAAAATTTACTTCTTCAGGGTATATTAACGACTTCAGATATAATTAGATTTATTTTATCTAGGAACAATTTAAATAAAGTGAAGGTTGCCGAAGTAATGACTCGGCAAGTAGTAACCTTAAAAAAGTCCCAAAGTAATAATATATTTACAGCATTGCAATTAATGCGCCAGCATAGAATCGGAAATTTACCGATTGTGAATGATTTCGAGCAAATAGTCGGAATTATCACTCAGGATAGTTTGCTGCAAAATTTTGATTTGCAAGCGCTACTGCAACGCCAAACTCAAACATATAATTGTTACGAATCGCACAAGCAAGTCAATTTTGAGACTCATGTCTTGAATAGACTTGGTGATGCAGTTGTTGGGATCGATAACGAGCATTGCATTATTTATTTAAATCAAGCAGCAGAAAAGTTATATAATGTTAAACTTGAAAATTTTGTTGGTAAACGGCTCGAAGAAGCTTATGATTCTCGTTGGGTGAATTCAGAAGACGAGCAAGCTGCACGTGATGCTTTGTCAGCAACAGAAGCTTGGCAGGGAGAGAATATTCATATAAAAAATAATGGCGAAGAAATCTTCGTTGAATCATCAGTTAACGTGCTCAAAGATAATAGTGGCGAAAATATCGGTTTAATTGCTGTGATTCGCGACATTACCAAGCGCAAACGTGCAGAAATAGCTATACGGGAGAAACTACAGCAACTAGAAACAATTGTTAACAATAATCCTATAGGAATCTATCGCTTTATCTATCATACTGATGGCAAAGTGTCTATTCCCTATGCTAGCGTTGGTTATCGCCAACTATTGGGTTTAAATCCGACTGATATGAGCGCTTATCCCGAAGATGTACTCGCAACAATTCATCTGGATGATAGAGAGAAATTTGCTCAAGCGTTAATAACTGCTACTGGGGAGCAACATCAATCGCATTATATGGAATATCGAGCCATTGATGTTTTAGGACAAGTAAAATGGTTGGGAAACAATTTTCGCTGTTCCAATCATACAAATGGCGATTTAATTGTAGATGGAGTAGATATTGACATAACACCTCGCAAACGTGCAGAAATTTCGCTACAAACTTCTGAAGAAAGATTTCGCTCTTTGGTAGAAATATCAAGCGATTGGGTATGGGAAGTCAACGAATATGGCTTTTTTACTTACGCTAGTCCAAAAGTATTAGATATTCTCGGTTACACTCCTCAAGAAATTTTGGGTAAAACGCCGTTAGATTTGCTGCCTACCGAAGAAGGTAAGCGGCTTGTTGAGGTTCTTAACTCATTTATTATAGAAAAACAGCAGTTTAAAAATTTAGAAAATATCAAGTTTCATAAAAACGGAAATTCCGTAATTATGGAAACAAGCGGCGTACCTATATTCGATGCAAACGGTTATTTTCGTGGTTATCGCGGTATTGATAGAGATATTACCGAACGTTTTCAAGCTGAAGATAGGTTACGTACTAGTGAAGAACGTTTTCGGGTATTAGTAACTCATGCTCCTGTGGGAATTTTTCAAACTAATGCAAAGGGAGAATGTTTATTTGTCAACCCACGTTGGTCAGAAATTACTGGATTATCCGAGCAAGAAGCATCAGGAGAAGGTTGGTCAAAAGCGCTACATTCTGATGATAAAGAGCAAGTGTTTACCGCATGGTACGATGCTGCCACAGCAGGACAAGAGTTTGCAATGGAATATCGCTTTTGCACTCCTGAAGGTAAAGTTAGTTGGGTGTTTGGCAATGCGATCGCTATTTGCAATCAAACAGGAGACATTACGGGGTATCTAGGAACTGTCACCGATATTACCGAACATAAGCAAGCTGAAGAAAAACTGCGCTGGACTCAGGCTTTGCTGCAAGAAGCCCAGAGAATAGCAAAAATGGGCAGTTGGTCTAGAGATTTGACGACAAATGAAAGATGGTGGTCCGAACAATATTACCGGATAATTAACTTGAATCCCGGTGATGCTATGCCCGATGTCGAAACCGTAATTAATTCAAATGTACATCCAGACGACCGCGATAAAATTTATCAAATGGTAATGGCTTGTATCGAGCAGGGTATTCCCTATGAAACTGAAGTACGTTTTCTAAATGCCGATAATAGCATTGGTTACGTGTTTATTTGCGGAAGGGTAGAGCGCGATTCCCAAGGAAACTTGTGTCGTTATTATGGCATTGTTCAAGATATTAGCGAATATAAGCAAGTAGAATTGGAGTTAAGAGAGAGTAAAGAACGCTACCGCTCGGTTGTAAAATCGATGCATGAAGGTGTAGTTATTCAGCAAGCCGATGGTACTATAATTTCCTGTAATGCTAGTGCCCAAAAGATTTTAGGGCTATCAGCCGAACAGATAAAGGGACGTAATTCTGTAGATCCTCGCTGGCGTACAATCCACGAAGACGGTTCTCCTTTCCCAGGGGAAACTCATCCGGCGATGGTTGCTTTGCATACCGGTAAACCATGTTTATATACGGTGATGGGAGTTTACAAACCCAATGGAAAACTTACTTGGATTTTGATTAACTCCGAACCGCTATTTTTACCAGGACAAAATCTTCCCTATCGTGTAGTCACTTCCTTTTCTGACATCACGCGACGCAAGGAAGCCGAAGAAAAAATTAAAGAACAAGCTCAATTGCTCGATATTACTACCGATGCAATTTTAGTTAAAGATTTAGAAGAAACTATTTTATATTGCAACAACAGCGCCGAAAATATATATGGTTGGAAGAAAGAAGAATTAATCGGAAAGACAGCCAACGAAATTTTATATGAAGAAATTTCACCAGAATTAGAATCAGCATTGAGCGAAGTTGTTGAAGCTGGCTCCTGGCAGGGAGAATTACATAAAATTACTAAAACAGGTAAAAATATTATTGTTGCTAGCCGTTGGACACTGGTGCGCGACAAAACTGGAAAACCCGAATCAGTTTTGACTGTAGATACCGACATCACCCAGACAAAGCACCTAGAAAACCAGTTTCTCCGCACTCAACGTTTAGAAAGTTTGGGAACTTTGGCGAGCGGTATCGCTCACGATTTGAATAACATGCTCACACCAATTTTGGCGATCGCTCAACTTTTACCCTTCAAGTTGAATAACGAAGAGCAAGATTGTAGGGAAATGCTTTCCATGCTAGAAGACAGTGCCAAACGCGGAGCCGACTTAGTTAAGCAAATCCTGACATTCGCTCGCGGAAATGAAGGTAAGCGCACCGTATTGCAAATCAAGCATCTTCTAAAAGAAATTGAGCAGTTTGCCAACAGAACATTTACCAAATCAATTGCAATCAACAGGTATCTACCGCAAGACCTATTGACAATTTCGGCAGATCCTACACAAATGCATCAAGTTTTTATGAACTTAGTAGTTAATGCTCGCGATGCCATGCCCAACGGTGGAACTATAACTATTTCTGCACAAAACCTGTACATTGATGAAAGCTATGCCAAAATGAACATCGAGGCAAAAGTTGGTAATTATGTTGTAGTTACCATTGCCGATACAGGGAAAGGAATTTCTCCAGAAGCTATTGAGCGAGTTTTTGATCCCTTCTTTACCACTAAAGAAGTAGGTAAAGGAACGGGATTAGGTTTATCAACTGCTATTGGCATCATTAAAAACCACGGTGGTTTTATTGAAGTAACTAGTGAGTTAGGAAAAGGTAGTCAATTCAAAGTATACTTACCAAGCACTCAGGATAAGAGAATCGAACCAGCACAAGAAAATATAGCGCTTTTAGGAAACTCAGAGCAGATTCTAATAGTAGATGACGAACCAGCAATTTGTGAAATTGTTAAAACTACATTAGAAAGTCAAAACTTCGATATTCTTACAGCAGCAGATGGCATCGAAGCAATTTCAACATATGTCCAGAATAAAACTGGAATTAGTATCGTGTTAATAGATATGATGATGCCAGAAATGGACGGAGCAACAGCTATAGCAACTTTGCAACAGCTAAACCCACAAGTCAAAATTATTGCCATGAGCGGATTAACATCTACTCAGACTTTAGCTCAAGCAGCAGGCACTGGAATTCAAGGATTTCTAGCAAAACCATTCACCCAATACGACTTGCTCAATACTATAAGTGGAGTTTTATCAGCGAGTAGTAATTAGCAATCAATCAACAGTTATTTCAGTAATGCCAGAATTATTATTAATTACCCATTACCTATTACCTATTACCTATTACCCATTACCCAGTTCCATAGATATGACAAATATTTTACCAGTCATGAGATTATACTTTGACTAGAAGATACTGACCGTTGCCGTTGTATTCACCGTCGCAAGTTGCAAAAATTGTTCCTAACATGAGTAAATAGAAGCGCCACATTCGACGAAACTTGTCGTAGTTCATGCCATAGTCTAAAGATTTGATTGTATCTTGATAATTATCAAATCTTTGCAACCATGCTTTTAAGGTTTGATGGTAGTTGATGCCGTTTATATACCACTGACTGACGGTTTTAAGATCGCGATTATGATTTGGAATCGCATTATAATTCCAGTAGCGCCCGTGAGGAAAAATGTACTTATGGGTAAAGCCTGATGACATATTGTTGGGGATACGAACAGTAATGATATGAATGAATGCCTTCCCATCACTTTTAAGAAACGACGCTACTTTTTGCAGGGAATTTGTGAGATTTCCAACATGCTCAAAAAGTCCGACTGAAAGAATTTTGTCAAATTTCTCGACGAATTCTACGCGATTTAAATCATCTTCATAAAGCGTAAATCTACCTGAACTTAGATAACTCTGAGAGTCTTGCATTTTGCGGCGTATATACTCGCATTGTTGATAGCTGAAATTCAGTCCCGTAAATCGTACATTAGGGAACTTAGACATAATGTAGTTAGCCACGCAACCCCAGCCACAGCCTAAATCTAAAATATGGTCGCCGTCAGCTATTTCTAGTCGCTCGATTATCAGATCGATTGCGTGCATTTGAGATTCTTCAAGATTCCTAGCTCCATCTTCCCATAATCCCATACTGTATTTGGGATAAATAACTTCCCAATCTCCCAACATCTGATTCAGCATAGTTTGGGGTAAATCGTACTGAAGTTTCATTAGCTGTTTTGAAGATTTAGCCAGACTATCGGATTCGTTTAATACCCATTCATAAGGAGCTAATAAAGCGGGACAATACTTAAAGAAAATGGGCATCGATGCGTGCAACAACAATCGAAAAGCAGAATCTGGTATTTCTAGACCATTGATGTAAGCTTCTGCTGAAACCATGTGAGCCTGATTAAGAATTCCAGCCATTAATCGTGTAGATTTATACGCAATTGGGTCTTTTAAAGATATATCTCCCATGATGGGAATATGCTTTTGAAAGCCTGAAAATACTTTTGTAGAAGTCATTTTAGTTTTCTCTTTATTTTTAATCCCTATCTGTAGCAGTCCTAAACTATTCAGGATTGCTATATATGGTTATTCTCGATTGAAAAAATTAGTGTCAAAAAACAAGTGCAAAGAATTCATTACCTGTTGACAAGCCTGGAGAAAGCAGCCTCAAGATAAAATCTTTGCACTCATAAAAGTCGAAGGAATCTGCAATGGAGCATATTTATCCCAAAGGATATAAGCTCATTAAGAGCAAACAATGCTTACTAACTGCTATTCATTCAATCTATTATAAAAATATGAGGAACTTGTGAGGATAACTTGAGTAGTTAAATCGAAATCCTTACAATCTAAGTGGGTATGCAAAATTATTTGTGTCATTGCGAGTGAAACGCAGCAATCGCAGAGTGTTGCGATTGCTTCGCTGTCGCTCGCAATGACAAATATAGCCGTTGTCAGTTGAGTAGAATACAACAGGTAACTACTCATTTGGACACCCCTCTCCTTAGTAAGGGGTGAGGTTCAGACTGTATTGCACCCAAGTGAAAAGCGCTATATACAATTAATTTTGTCTAAGTACTTATACTCCCTTCCCGATAGAAGATTTCCTATAAAAAACCGCAGAGAGCGCAGAGAGCGCAGAGGAAAGAGCTAAAAATAGATAGGTAATTTTAGAGTGAGATAGGAGTAGCTTTTGAGAAATTAGCACTTGTTTCCAATATTAGTTAAAACTAGAAAGTCATAAAAGAAAGATAGTTCACATCTTGCACCATTCTCATTCGCTAGAGCCGGAGCCTTTAGAACCTAGTTACCAGGTTTAATCAGGGAACTAGTAATTCACCAAGCTAACTTTGCGGAGTCCATAAAAAGAAGAAAAAGTAAGAAAATAATTTTTTCTTCCCCCTCCCTTGCCTCACTCAGCAAATTTGCCTTGCTTGAGAACTAGTTGGAGAGCCTCCGACTCTTGTTAAGACTGGTGCAAGATGCGAACGTAGCAAACTTATTTGATATTTCTTCACTAGCAGAATCAATTTTTATTGCTAGCGATAACACCTCCGATAGGCAAAATCAAAATTTCATGGCTATCGCTTTCCGTAAACTCTTGGTTTATTCCGATGCCCTTTACATCATAATAGCGTCTTGGATTTCAAACCCCGAAGGAGCCGTTGTCAAACTAGCGATGGCTTGATTTTGGAACAATATTTGGTTGCCTTGGATATCGAAATCACTAATGTTGCTGCTAAAGCCAAAAGTGAATCTATCACCTTCAAAGAATCTAAAGTCTGTAATGGTGTCAAAGCCTTGAATATTAAATAAATCTGCACCTGCACCACCAGTCAAAGTATCCGCACCAGCACCGCCGATCAAAATATCCGCACCAGCGCCACCAAATAACCTGTCGTTGCCGTTACCACCGTTTAGGGTATCTCTACCGGCACCACCCCGCAAGATATCGTTACCGTTACCACCTCTGAGGTTATCGTTACCGTTACCGCCTAGAAGACTATCATTGCCTCCGTTACCAAATAAATTGTCATTTCCAGCGTTACCAGAAAGAGTATCTCTACCAGCACCACCCCGTAGGATATCGTTGCCGTTACCACCTCTGAGGTTATCGTTACCGCTACCGCCTAGAAGACTATCATTGCCTCCGTTACCAAATAAATTGTCATTTCCAGCGTTACCAGAAAGAGTATCTCTACCAGCACCACCCCGTAGGATATCGTTGCCGTTACCACCTCTAAGGTTATCGTTACCGTTGCCGCCTAAAAGACTATCGTTTCCTCCGTTACCAAATAAATTGTCATTTCCAGCGTTACCAGAAAGAGTATCTCTACCAGCACCACCCCGTAGGATATCGTTGCCGTTACCACCTCTAAGGTTATCGTTACCGTTGCCGCCTAAAAGACTATCGTTTCCTCCGTTACCAAATAGATTGTCATTTCCAGCGTTACCAGAAAGAGTATCTCTACCGGCACCACCCCGTAGGATATCGTTGCCGTTACCACCTCTAAGGTTATCGTTACCGTTGCCGCCTAAAAGACTATCATTTCCTCTATTGCCAAATAGATTATCATTTCCAGCGTTACCCGAAAGAGTATCTCTACCGGCACCACCCCGTAGAAGATCGTTGCCGTTACCACCTCTGAGGTTATCGTTACCGTTACCGCCTGAAAGCGTATCTCTTCCGTTACCACCGCGCAGAGTATCTCTACCGTTGCCACCGTTGAGATTATCGTTACCGTTGCCGCCTAAAAGACTATCGTTTCCTCCATTGCCAAATAAATTATCATTGCCTGTAGCACCTGCAAGCGTATCTCTTCCAGCACCACCGCGCAGAGTATCTCTACCCGAACCACCATCAAGGTTATCGTTACCTATACCGCCCTGGAGACTATCGTTATTTTCGTTGCCAAACAACCTGTCATTACCAGCATTGCCCCGCAACGTATCGTTACCTCTCAAACCAATAACCGTATCATTACCTGCTAAAGCGTTGATTAAGTCAGGACCATTTGTCCCTACCAGAAAATCATTGTTATTAGTAGCCATGTCAAAAATCCTTTGTGGCTTGATATTGAAGAGTGAATATGCAAAGAGATGGTTAAAACAAAAAATGATTTTTGATTTCAATCTCTTTAACTACTAATAGTTGTATCTAATTTTTGTTTGCTTAAATATATTTAGCTAAATTTTGATATTCTTTTTTACATAATGGTTAACTTTCACTAAAAACGATTAGATTAATTAATATACGCCATTTGATATATTCTCTTGCTGCTATTTATTGCCACAAGAATTAGATAGAGTTTGCATATGCAATTCACTTCAATAAGCTATGCTTTTGTTTTGTTACAAAACTACAATCTCTAGATTATTCTAATTTCTAATTATTAATTTTTCTTCACGTTTAATTGAGTTAATGTCTTTTATTTTAGCTTTTTAGTGCAACTATACTATCAGTTGATTAACAAATAATGAGTTAATCCGTTCTAGATTCCCTCACAGTTTCCTCATACTTATTGTCTACAATCGAATTGTTTAAGAATTGTCTTAGTTCCCTAAGTCAGATTCAATAAATAATCAGGGGCGCTAGTAAAGCTATTTGATTTTAGTCAGGAATGTCCGCAATTGTCACAGTGTCCCGTTGGTGCGTGACACTAAAAACATTATTACTACGTTCATAAATAGTCGAAGTGTCACAGCACCCTAAAAGATAAATATGCCAGTTGCGTAAGTCCTATTACTAAAATAGCGTCCCCTGAAGCTAAAATAATTTAATTACACTGATGGTTTTTTTGGCTTGCTAATTACTTATTACTATTTTGACTGAATATTTAATTGCGTAGATATTTGCTGATTCATTATCATTGTTTCTGGAGAATTAGGCACGGTTGTACGCATTTGAGTATTTGCATTCATTTTGAGCGATGTACTTAAAGGCATAAGTCGGTTTAAAGCGATTTTTGATTGTCCCGTGCCATTGGCGTTGTAAGATTCCATAATCATAGTCATACCTTTGGGAATTTGGGGTAATGCTATTTTTTGTGCGCCGGGTGCTTTTTGCGTTAGATTGATATTCATTGTTGCAATGCCATCTTGAATATCAACCAATTCGTAGTTAGCAGTTTGCACAAGGGTGATGCCATTGAAGCTAATGTTAGAAGTAACTTTCCATTTTGCACCTTTACCGACTGCTTCTGTGGGAACTTGAGCCGATAGCTGTTCGATGGAATTTTTCAATTGATCCATCGTTTGTTTTAAAGCTGGGTTGAAGTTTTTCGGGACAATAAAATTAGCTTTTTTAGTCTGCCCCTTATTATCAACAATTACATTTCCTTTTAAACCTTGCATTTTTTTTATTTCACGGCGCATATCTTCCAGAGCGCTGGGTGGTAGATTGCTTTCTCCGACTATATCGACATTGTCATAAGAAAAATCATAATAAATATCGCCATTTTGTTCTACCTTGTTGACGGTAGTATTTAATTTCAAGCTGGTTCCAGGTATTTTAAATGATGGTGCTTCATTACCATTCACAGACATGGACATATTCATATCCATTTGCATATCAGCAGTTTCTTTTTGTCCCGTTTGGGGTACAAAACGTAATCTTTGACGCGGTTGTGCTCCTGGTGTAATTAATCGAATTTGGGATTTAGTTTCTGGCTGTGGGGATAGCTGATTTTCAAGCGGTGTTTGTGGTTGTGTTGTTTGAGCAAATGCACGATTAAAAACGGGTTGTAATCCGGAACCAATAATGGTGAGCAGAATCCCACCAGCTAACAAGCTTTTTTTGGTTGTCATTATTTTTTACCGAAGTTTATATACTTATATAATTCAGTTATACAAGCATTTATTCCCGAATCGATTCATAATTAACGATTTTCACTTGGATGAAATCCAGGTAAACCTCACTTTCTTCCCCTCTCCTCGTTGAAGGGATGCCCAAAGCTGTCTGGAAAAAATTTGTGTAGTGTAAATTTAAATCTATACGCAAACCTTTAACCCCACTCCCCAGATACGGGAAGTGGAGTTTTAAACCCTCTCAGGAATGGGGAGAGGTAATCTAGGAGAAGACAAGGGGTGTTTCAATACTGCTCGGTTAAGGAATTGGACACAATGGTTAGATCCCCCAAACCCCCGCTAAATTGGGGGCTAAGTTCCTTCCTTTTTAAGGAAGGTTAGGGAGGATCTCCTCTTAACCGAGCAGTATTGAGGGGTGTTTTTCTTTTTCGGACTATTGATTATTGAGACGACTGCAAGCCATGCATATGATTAAACAAATTCCAGCAATATTCTTCAGGTAGCTTGCAGGTAATCGCACCACGCAATACAACGTTGAAATACCAATCATTGGGAGCAATTTCTTGCAAAAGTTTGTTCACCACCACGTATGTGCGGACTTTTTCGTAAGTCTTTCCTCGAAAACTAATATCGACAAATTCTTGACGGTAGCCACCACGGGGTACATCTTCGCGTTTATCTAGACTGGCGCTGAGTCTTAAAGGTAATCGATAAAGTACCCCATGCACAGTACTTTTTGAATCTTTTACCACATCCAAAACGCCACATTTACGAAAAGCGCTATAACGGTAAAATCCCAATCGATAGCCCTTTAAAACCCCCGCACCCATTACATAATGGTGGGTATTTTCACCCATAGTACGCTTTAAATCTACCGGACACATACAGGAACCGTAAGCAAAATAATAAAACATCGGTTCCTTTGGCTGCAAGTGTTGTCTATTATGAGATTCGCGGTGAGTGCGATCGCTCATCTATCTACAGAAATATTTATTACAACTGCCAATATATCAAAAGATGGGGCTTGTAGTTGCGCTTCAGCGCCAAATGTTTATGGCGCTGAAGCGTAACTACGAACATATATATTCCCAATGCTAAATTCCCAAAATTAACTTCTTAAAATCCGATTCCAACTTTCGACAACAGTCAGCAAATCTTTGGGTAAATTTTGGCGGGAAGTGTCGTTAAATTGCACCGTACCGTTACGGCTGGTAAGGGTGTATACCATATAATCTGCGGCACCTCTGGCGACGGGGTAGCTCATATTTCTAAATTCATCGCGCTGACGCTGCAATAATCTTTGAAAATCACTTACTTGTTTGCGAGAAACTTGACGAAGATTTCGACTTGAATCATTCATGTCACCTATGCGATAGCGCATTATCCGCCCATCTTCAAATAATATTGTTTCGTAAGTTTGTCCTGCAAAACCACCGCTGGTAATTTGACGAAATACGATTCCTCTAGTTAAAGGTGATGGTAATTCACCTCTGGGAATTCTGACGGGTAAAACTGTGGTGGGATTGTTGTTAATTGTGCTGACGGTTTCGTTTAAAATGACTCTGGATCTACTGTCGGTATGGTAAACCAATGTTTCCGAACCAACTTTTACCGTGACTCGGTAGCCTTCTACAAGTCTGTAAAAGCAATAGCGCTGTCTGCGTTGGCTAACTATACCCAAACAACCATTGCGCCATGTGACTTTTTCGGCTTCTACAATATTTTCCGGGGATACTCTAACTCTACCTTGGAGGCGTTCCCTGGCATCGGCTAATACCCCATTTTCAATAGATTTTGGCAAGCTGACGGTGCCATCTAGTTGAAATTCCGAACCATCTTGTTTAAAGCGGTAAGTCCAAGTTTCTCTACCGTCGGATAAGGTAGCTTTCATCAGGGGGACGTTATCTTTTCTTTCGTTGAGTCGTTCAACTTCGATAACTCGGATTTGATAAGCGCTGGATGCCCTTTGAGAAAGTCTTGCGGCATCTTGTTTAATTACTCCTGCGGCTCTTTGAGTTAAGCTGGGGGTACGGTCAAGAGCTACTATTGAAGCGTTATCGTTAGCATGGTAAATCCAGGTTTGGTTGTTTGCTTTTAATGTCACAATCCAACCGGGAGTACGAATCAACGCTTTGTTGCAAATTCTATTGAAGGTTAAGAAACAAGGATTATTCCAAATTTTGCGCTGGCTGCCGACAATTTGTATTCTTCTTGAAGGTAAACCACTCCATTTTGAAGCATCTTTGAGGATGCTATTGGCAACAATTCTCGGTAATTGAGTTTGCTGGCTATTTTGGTTGGATAATTTGACTTGATTTCCGGTAGCATCGGTGAAAAATACCCAAGTTTGCGAATCTCCACTGACAGCTACCTCCCAACCGGAAACAGCAACTCTGTCACAAGGATTATTGAAACTAAAATCTTCACAGCCGTATGCCCAGTTTGCTGGTTTAAACGAAACAATTCCTAATTTTCTTCCCGATAAACCAGAAATATTTCTTGCTTCTTTCAATACGCTATTGCGAACCCTTCTTGGCAATCTTAACTTGCTAGCTGCTGCATTCAAACGAATTTGATTTCCATCAATGGAAGTGTGATAAACCAAAGTTTGTCTGGCACCTTTGACAGTAACTCGCCATCCTCTTTGATTTGCTCTTAAGCAAGATTCGGCGGCACCTCCTAAATTCAAGCAGCTATCGGTAAAGGTTACTTGTTCAGCTTTTGTAACTTTAACTCTGGAGCTAGCAGTTAATTTCGATGCAGCTTTTAAAACGGTTTCTTTGACTTGAGAAGGTAAGCCGTTATCGGTAATTTCACTAGCTTTAACATTCAGTTTAACTACCGAGCCTGACCTGTTGGTATGATAAACCAAACTTTGCCCTTTGGTACCTACGATAACTCGCCAACCCGGTACTAAAACTTGGGAACAGATGGTGTTAGCGTCTCTTAATTCCAAACAGCCATCTTTCCAAGTTTTCTGCTGTGCCTGCATAATGAAAAAGCTAGAAACCGGCTGTTGCAAGCGTCGAGCAGCATCTGCAATTGCTCGCGATTTAACCGATGCTGGTAATTGCGAACCAGAATCATTAGAATTACCTCCAGAAGCCAAACGCAGCTTCCGCCCGTTATTATCAGTATGATAAACCCACCTTTGATTTCTATCGGATACCGTAACTCGATAACCCGGAACTAAAGCCTGGGTACACATTTCACCGGGCTTTAGTACTTCCAAGCATCCATTACGCCAAGTTTCTTTGCTGTAACCGACAACTCTTAATTGTGTTTGAGGTATATTTTGATTACGAGATACATCTTTGATGACAGCATTCACTACCGTAAGAGGTAAACCGCTTCTGCTGCTATTTTGTCTCTGTACTTGAATTGTGGTTTGAGAATTGTTTTGTCTTTGGCTAACAACTCTATTATTTTCGGTATTACCTAACTTATAATTTTGCGATGTAGGTACAACCACCGGCGTTGCGATCGCGCTTTTTAGTAGTGTAAATTCCGACGCAACAGACACAATACCAGTTAGTAGTAAAGCTGCAAATATCTGTGTCCTATTAGTAGTATAATTACCTTGAGATGAAGTCATAGCAAAATTACCTGTATCCGTCATTAGTTTACAAATAGTTAAAATTTGTTTCTGATGTTTAACTAAAAATATAAAATATAAAATCTTTGACCTTTCTAGCAAATACTGCTTTAAAGCAGCTAAACACAAAGAATTAATTATCCCATACTATAAAGCTTAGTAGGAAAAAATATAAGTTTCGCGTGTGTGTTTGTATACGAAAATAGACCTATACGTTAAATAATTTGTTCCTGTTTTATTTATCAAAACTTTATATAAATAGGTTTGTGTATTAGAGGTCTGTATGTTAAAGGTTAAATCCAATATTCTAATTAATATAGAAAGAATCATGAACAATTTTGAACAAATCCAAAATACCTATAAAAACTATCGAGATGATTACAGTTTAGAGCAGAGGAAGAACTGGTACAGTAAAGTTGCGGATGCGTACAACAAAACCAGACCGCGCTATCCCCAGGAACTGATTAATCGTACAGTAGAATTAGCTAAACTCAGTAAAAATACGAATATTTTAGAAATAGGGTGCGGTCCTGGAACTGCAACAGTAGAGTTTGCTAAACTAGATTGCCCAATGGTGTGCCTCGAACCCAGTCAAGACTCCTGCAATTTAGCGAGACAAAATTGTGAGAGTTTTCCCAACGTAGAAATTATCAATACCACCTTTGAAGAATGGGAACTACAGCCAAATAAATTTGATACCGTACTTGCTGCAACTTCCTTCCATTGGGTTTCACCGGAAGTAGGATATCCCAAACTAGAACAAGCATTAAAAGATAATGGCAGTTTGATTTTACTATGGAACAAAGAACCCCAACCCAGCTACGAAGTTTACCAAATTTTAGATGAGGTTTATCAAAAACAAGTTCCTTCCCTTTCCCGATACGAAGACAGGGGAACTACAGAAAGAATTATTCGGAAATTAGGGGAAAACATTGCAAAATCCGGGTTATTCAAAGATTTGGTATTTGAATGTAGGGAGTGCGATCGCGTTTACAGTATTGATGATTATCTAACCTTGTTGAGTACGCTATCACCTTATATAGTATTGGATGTTCAAAAGCGAGATGCTTTATTTGATGATTTGAGAAATGCTTTAAGTAAAAATCTTGGGGATACCATCGAGACATCATATCTTTCAGCATTTCACGTTGCGTGGAAGAAAGGTAAGTCCTAGATTTATAGATAAACTTGAATTTAATCATCTATTTCGTTTGGCATTAGGAACTAATTATGAAATTACAAAGAGTTCAAGTTCCAGATTTTCGCGTTTTGAAAAACGTTGATATATCTTTTGAAAAGGATTTTGTACCAAATATTTTTCCATTAGGTAGTCAAAACGGTGGTGGTAAAAGTACGCTTTTACAGTTAATTTTTGTATTGCTTCATTGTTCTGGTGATAGTGATAAGCATGAGTTTATCAAAAATATGCTTCATGGGTTTGAGATTGATGATGATTCTCAGAAAAGAGTTTTAGCGCGTTTTGATATTTGGGATGGGGAGAAGACAGTTAATCTGGAATTTGTTGTTTATAAAGATTCTTATGCGAGAAGATTCTTACATCAGAATAATAAACCTCTTATTACGATATCAGAAACTGTATTTTGTCGTATTGATAAGATGGATATCGATAAAGCTAAAGATTTTCTAAATAATTTATCAAGCAATATTTTTTTAGCAGCTCCTGCCACTCAAGTTTTTCTGTTTCTTAATAAAGACTCTAGAGATTTTCTTTTTAAACACCAAAATAATGATTACAGTAATAATTACTATTCACAACTCAAACAGTCACAGTATAAATTATCCGTTTTTTTTACATACGATTTTTTAGCTGTAGACCTACTTATAGATATTTTTCAGGCAGCAAGAGATAAAGACTTCAAACAAGCTATAGAAACAGGAGAATACGGAAATAATTATCAAAAACTTGTAAACGACTTAAATCAAGTCTTATTAAACAAAAAAATAAATATCAATCCTGATTTATCTGGCTTCACTTTTAAATTAGATGCAGAAGGAAATGATATAGAGCTATATCCCGAAGATTTAAGCCACGGTGAATTAAAACGACTTAGTATTTATGCTTGGATAAAGTACAATATTATAGAAGATTCAATTGTTTTAATAGATGAAATTGAAAATGGATTGCATCCAGATTGGCAATATCAAATAATTAAAGATATTGCTGAATGGGCACCAAAGAATCAATATATTATTGCTACTCACTCATATGAATTGTGTCAAGCAGTTACTCCCGCTCACGTTAAGGAATTAGAACCAAGGTTAATAAAGCAAGAATCGGAATAATAAATATGAGTCTGAATTCGGAGGAATTACAGCAGCATTGTCAAGAAATTATTAAGCAACGTAGAATTAAAAATAAAATAGTTATTCTTTGTGAAGGTGAAATCAGAAAAAATCAAGGTAGACCATCGCCTCAATCATATAAGAAAATGGAACAAATGCCAGATGCAAATTTTTATCATGCGTGCGTTCCAAGTTCTTGGAGACAGTATCGACCACAATTTTTTAATTGTGGAGATAGAAAAGATGTAATAGATACTTACTTTAATATTTTAAAATTACATAGTAAAGATACTAATAACTCATATTTAAGTCCAGAAAAGCTGTTTGCAATTGTAGATTTAGATATTCAAATTAAAAAAATAACAACAGAATACGATTATAAATTTTCAGATACAGAAGCAGCTTTTACACATCTTTATGATAAAGGTAAAGTTAACCAAGAAAATATAGCGGAACATCGTATTTGGGTTACGGGTTTAATCCATAAAGAAGCTTATTTTCTGACACCCGAACTTCAAGAAATGTTTGATATCTCTTTAAACACTCCAATTTATGAAGGAAACAAACTCTGTCTCGAAAAAATCTATCTAAAAATGGCAGATGATATTATTAACGATGTTGATTTGCAAAGTCACATAGCACAAGCATCTAATCGTATTGATTATTGTAATGGATTAGATTGTAGTGGAGTAGAAGAATTATGCAATTCATGGAAGTCAGAATTTAAAGCTTGTAACGATGAATTACGGAAGCATGAATTAATATATAGTTTACTGACACTTAAAAAAGCCAAATATTACTGGAATCAAATCCAGGCACCCGAACATTGGAATAGTTCTATTGAAGCATTCAAAGACCAACTTTTATTAAAAATCGGAAAATTCTATTCAGAAAATAGCACTAATCCCAGATATCATATTTCCTTTTTATTAGAAAATCTATCTATATCAAACATTACCAAGCCACTCTAAGATTAATGATAAAAATTTTCTCCCCCCTCTTCCCCCTCTCTTCCCTAACCTTCCCCCTTCAAACGCCATTCATCAACATTCCACAACAATCCCCCCACAGCAGAATACTCTACATTCTCCACACGATTCCGCACTGCTTGTAAAGATACGGGATTAACTAAGAAAAATACTGGTAATTGTTCGGCTACTATTTGCTGAAATTCAGCATAAATTTGTTTTCTTTTATTTTCATCAGCTTCTTTAGCTCCTTCTTGGAAAAGTTGGTCTATTTGTTTTTCCCAATCATTTACTTTCCAACCTATAATAGGACGTTTTTTAGATTTGGAACCTTTATTAAACATATGAAACGAACCGTTACTAGTCCAAAACAAAGCGATAAGATTCGGTTCAAATATTGCTGATTCAAAAGCACCGACATAACAGTCCCAATCTCGTTTTGTGAGTATTTTTTGTAGTACAGTATTAAAGCTGAGGGTTTGTAAATTTGCTTGAATACCAATCTGTTTTAAATCTTGTTGAATTTGTACCGCAGTAGCTACACGAGTTTGGTCTTCTGATTTAACTAATATATTGAATTTTACCTGATTGCCATCTTTATCCAGTAATTGTTGTTGAGAATCATACTGAAAACCAGCCTTAGTTAATAATTGCTTTGCTTTTTGAGGATTATAGCTATATGTCTTTAAACCTTGTGCTGGAGATAAATAATAAGGACTTTGCACTGCAATCGGTGAATGTTGTAACTCACCGATTCCTTGATAGATATTAGTTTTTATTCTATCGCGGTTGATAGCATAAGCAATTGCTTGGCGAAATGCTAAATTATTAAACCAACGAGATTTAACAGGATTTACAAAAGGTTTTCCTTGAGAATTACTAGCTTGATTGAGATTAAAAGTAACAAAACGAATTCCTTGACTTAGTCCACCATTATAAATACTGAAATTACCCCGCTTTTCTTCTCGTTTCAGCAAAGCAAAAGTATCTGGTTTAACCCTCAAACTATCCAATTCCCCCGAACGAAATCTTAGTAAATGGTTATCGGTGGATGGAATAATTTGCCAAATAATACTTTTAATATATGGCATTTGTTGCCCTTGAGCATCTTTACGAAAATAATAAGGATTCCGTTTTAAAATAATTCGTTCGGAAGGAGTATAGCTTTCTATTTGATAAGCACCATTAACAATAATTTTTTCTGGTGCTGTATCGCTTCCCCAAGTGGAAAGAAATTGAGGATTACCATTAGCATCATTCGATAAAACTGAATCGCGCAAAGCATGAGCCGGTAAAATAGCAAGACTCGCGGACTTTCTTAAAAAAGGAGTAAAAGGTTCGGGTAAACTAAACTCAATGGTGCGATTATCTAATTTCCGTATTTCAGGAAACACATCTTGATTCCCAATCCGCAGAAAATCTTTAAATAAAGTCGGAATCTTTTTATTAAGGTAAATATCTTTATAGGTAAATATGACATCATCTACAGTCAAAGGTTTACCATCCGACCATTTTAGTTTGTCTCTAAGCTTAAAAGTAATTCTTAGCTTATCATCTGAAACTTTCCAGGATTCAGCTAAAGCAGGTTCTAATTCATTTGTTTTACCATTCTCCGTAACTAATCCCTGATAGATGAAAGGAAAAACGCTGAAAGGAGAATTATTCATTGCATAATTGAATGTAGCTACATCGCTAGGAGTAGCCAAAGTTAACTGGGATTGCTTTACTTTCCTATCCCATGATGCATCACAAGCTGTGAGCATTGCAAAGCAAAAAGCCAGCATCAAGATAACTGTTAAACGTAGATAGCGAGACATAACAAAACCTGCACATAAATGTCAGCTATTACAACATTAATAATTTTTGGCGGATTGCGATGATTATTTTAGCTAAGGTTCCAAGCTTCGCTAACAGAGCGCGATCGCGAACAGCTTGTTTGCATTTCATTATGGAAAAAATAAAATATTATTCTACCCCCCTCTCTTGTTTCCCTTCCCTCACCCTGCAATTTTGGTTTGGTGAAGTACTAGAATGACTATCACCACCTTGCTTCGATTCTGCTACAAGAAAAGTATCGCCATTCTCATCAACTAAAAATTTTTGGGCTTCAACAATTTTACGAGTATATTTAGTCGTAGATTGTCTAGATAATTTACCTATTCTCCTTGGAGTGATTTGCGACTGTAAATCAACCCATTTTGTAATTACCGCTTGTCCTATTAAAGGCTCGTTAGGACTTAAAGGTAACCCACCTCTTCCCGTTGCGATAAAGCTGCTTTGCAGTAGTCTTCCTCTGGGAGTACAAGCTTGATCGATTTCTTGAGATGCATCAACTAAGTTTGTGGGTAGTTCGACTAAACCGCTAGCCGGATCTACATCGGGAGTATTAATAACAGGTTCGCGACTTAAATCGGGACTTTGCTGAGAAACTGCCGTAATGTCGCTACTGGATAAATTATTAGGATTAAGTTCTTCTGGGTTATTGGTTGCCAACCGTTCAATCAGTTTGTTTCTAGTTAGGGGTGCGATTCCCAGAATACTGGTTGCATTTATCGAAACTCCTCCCCCGCTGCCGCTAAATGCATTGGCTGTAATATCGCTATTCTCATTAGGAACAGCAACAACAAAACCGTTGGGAACATCAATAGAAATGTTACCGCCGTCGCCACCAAATTGCTGATTCCCTGCGGTGCTGGTGATTTGGCTACCGTTGCGGAGTAATAATACATCTTGCAGATTTAGAGTAATGTCACCGCCAGTATTGCTGCGGGTTTCGGCGGAGATGGTTCCATTGTCGAGTGTGAGGAAGCCTGCTGCAAGTTCGATATCGCCGCCAATTCCTTTCCCTTGACTATCTACAGCGATTCTCGCACCATCTCGAATTGTCATAATTTTGGGATCGATGATGATACTACCACCTTTGCCCGTTGAATTTTCCAAAGTACTAGCAAAGATTCCGGTTTCGCTACCTGAGAGGGTAATATTTTCACTCACATTCAAAGTAATATCTCCGGCTTCTCCACTGCTAGAGGTACTGGCATTAATTTCAGCACCATTGGTAACTTCAAGGAAGCCAGTTGTAATGGATATACCCCCCGCTTTGCCCACTGCTCCAGATTCAACAGTGCTCAATGCCTGACTTTTATCCCTATTTCCATCCTTACCTTGCCCATCAAACTTAACTTTGGAGGTGGCATTAATAGTGACACTGCCAGCATCACCTTTTCCAAATGTAGCAGCACTAAGTTCGGCACCATTGGTAACTTCAAGGGAGCCAGTTGTAATGGATATACTCCCCGCGTTGCCCACTGCTTCAAGATCCACCTTGCTGAATACCCCACTGGAAACTCTATCCTTCCCTTCTCCATCAAACTTGATGGAGGTGGCATTAATGTTGACACCGCCTGCATTCCCTTTTGCAAAGGTACTGGCACTAAGTTGGGCACCACTGGTAACTTCAAGGGAGCCAGTTGTAATGAATACACCCCCCGCATTGCCCACTGCTCCAGAGTTCACCTGACTGAATGCTCCACTACCCAAGGATCCATTCTTAGTTTCCCCATCAAACTTGATAGAGTCAGCGGCTTTAATTGCGACATTACCAGCATTACCTTTTCCAAAGGTACTGGCAGAAAGTTCGGCACCATTGGTAACTTCAAGGAAGCCCGTCGTAATAGATACACCCCCTGCTTTGCCTTCTGCTCCAAATTCCACATTGCTTCTTGCCCCACTGGAAAATCTATCCTTAGTTTCTCCATCAAACTTGATAGAGTTTGTGGCATTAATGGTGACAGTGCCAGCATCACCTTTTCCAAAGGTACTGGCAGAAAGTTGAGCACCATTGGTAACTTCAAGGGAGCCAGTTGTAATGGATACACCCCCCGCATTCCCCACTGCTCCAGGTTCCACATCGCTGACTGCCACACTGGGAATTCCATTCTTACGTTCGCCATCAAATATTACCTTGCCAGTGGCATTAATAATGATACTATCTGCATCACCTGTTCCTTTGGTACTGACACCAAGAAAGCCTCCAGAGAGTACCTGAAGTGAGCCAGTGGTAATAATGATACTGCCCCCATTTCCTTGTCCTTGTCTTACAATATTGGAAGTAAGTCCGGAACCATTAGTAACTTGAAGGGAGTCAGTGGTAACTAATATATCTCCGCCATTACCCACTGCTCCAGAATTTACATCGTTAAAAGCATTACTATCATTATCAAGCAAAACAGTATCGGTGGCATTAATTGTAATATCTCCTGCCTGAGCCTCTGGCGTACCCAAACCTTCACGAATCCCAGCCAAAAGTTGACTCTCTTCTCTTACCTCTAAATTCCTAGCATTAACTGTAATTGAGCCTCCCCCACCAGCACTCACATCAATAATTGCACCATTGGTGAGCGATACATCGGCTCTTGCCACATCATCGGGTACATTCAAACTCAAGTCGTTACCATCAACATTTAAACCTACTGTTCCATTACCTGCTAACCCTGCCAACTCCAGCCTTCCACCTAAAGCACTCAATCCCCCTCCATCAAGGTTGATATCTCCACCTACCAGCAAGAAGCTACGATTATTTGGTACTCGTAGATTTGACTTACTTTCTATTTTTCCCGGTTGAAGTTGATTGAAAAATAATGCTGAAGGATTTATTGTTAGTAGTTGGGAGGGAGGTTGAAGATTTGTGGCGCTAAAAAAACCTTGCTCGCCAAATTGAATTGCATTCGCGGTACTCGCCACGAAGGAACCATTCACATCTAAACGCGCATTTTCTCCAAAAATAATTCCACTGGGATTAATTAAGAAAAAATTCACATCGCTACCAAGAGTGCGAATTAATCCGTCAATTGAAGAAGGGCTACCACCAGTCACCCGCGACAGAATATTTCTGATATTACCTGCACTTTCAAAAATAGCGGCTTCATTACGATTAAGATTAAACTTCCCAAAGCTGTGAAATAAATTATTCCCAGCAGTTTCTCCCACCGATTGGGGAATCTGATAATTTGGTCCTGTTAAAGTTTTTGGAGTTCCCAAGCTGCCATCTAGGGTGATGTTTTGCGCCCTTGCATCAGTGGTAGAGTATGCGAACACCACACCTACCGCCAAAGTACTTGTTAGTATGCCAAGCAATCCTTTAACGATATGTCACCCCCAAAAATTTCCTACATATGGATATAGTTTATGGGTAAATACGGTTGTATGCTACAAGAGGGCTAACATAGTTTAAAGTGACACAATAAAGATTGATTTTTGGATAAACATATGGAATTTTAAGCTCAAAATAGCAAATACAACATATTCACAGGACTTATTGCCCTATCTTCGTTATTTTCAAACAGCTAGAAGTCTTCCGTTAACAATCACTATAGCTGTAAAAAATTTGTCTTTCTCAAAAAATCAACGGTGGCTATTTCGATAGCATCAGATGCACCACTCGAAGCATCATGGTGGCATTCAGGCAGTACTTGAAATAGAGATGATGGAATTAGTTGATGCAGTTGTTTTCCGTGTTCTATAGGAAACCAAGTATCTTGTTCTCCCCACATTATTAATGTGGGACATTCTATATTAATTAAGTTATTCTGAATTTTACTCAACCAGTTGGGCTGATTTTTTTGAGCGTTTTCGATTTCTCGGGCTGCAATTTGTAATTCTTGAGCTACTTTAAGAAAAGTGCCGGGAAACTCAATATAGGGATAAGTTATCCAAAAGACATTTTCCTGAGTCAAAATAGAAGGATCGAATAATACGCTACGTCTTTCGATTGCCATGATTTCTCGAATCAGTGGTGCGAATAAGTAGCTTAAACGCAATTTATCAATTACTTCGATTATTTCTAAGGGTGTTTTAGCTAATAAAGACATTCCCCAATGAGGAAGTTTTTTCGTGAATATCGGTACATTCACAACTGCTAAATGAGAAACTAGTTCGGAGTATTCTTGAGCAAAAGCCAGAGCAACTAAAGCACCTAAAGATTCGGATAAAATTGCTACTGGTTCATTACATAATGCAGTAATAATTCGTTGTAATTCAATAACTTGATGACCTGTAGTTTCTTCGCGATGCAGAGGTTTTTCTGAAAAGCCAAAACCTTTAGCATCAAAACAAATTACTCGAAAATATTTAGATAAAGGTTCGATCAGATTGCGCCAGTTATAGCTCCAGCTACCAATACCATGTAACAAAAATAAAGGTTTTCCCTTGCCTTTTTCACCATAGGCAATTTTTACGGGATAACCTTGAGAGTCGGTAATAGTTATTGTCTGTTTTCCTTGTGGGAAAGTATCTTGCCACCAGTTTTTCATATCAATTAGCAGTTATCGGTATAAATTGGGTCATCTTAAGCCGTTAGGAGTGATAAATGTTGAAGTTTTAATTGGTGACTGTTAACTTTTAACTACCTGTAATTAGCCCCCAAACAAATCTGGAAACGACTACGGAAAAGGTTACTAAACCGATAGCAAGCAATAATAATACAGCTATAAGTACAAACACAAACCAAGTATCGGCTCGTTTCTTTTGACTGGGAAATTTTAAATGTTCCTCTAATAATTTAATATTATGGTCGTTGGCTTTCCAAGCAAAATCAAAGAAGTCTCCTAGAATTGGTACTACACCAATCAAGGCATCAATTATAATATTCATTGTCATTCTGCCTAAAGTTGCTTGAGAAGCACCCAGTCGTGCGGCTTCTAAAACGATATAAGCTGACAGCAGAACACCTAAAAAATCACCACCTGCGGGTAGTAATCCTAGAATTGGATCTAAACCTATGCCGATTCCAGTTCCAGGAATTGTAATCGCTTTATCTAATATGCGACTTAAAGCACGCAGACGCTTTAAAGTTGGTGCTTTAACATCTGGATTTAGAGAATAAAATTGTGAGGGTGGCAAGGACATGATATTAATAACTTTTAGATGATGAAATGACCGTTTCTTTTACTGTTATAGTTGAATATTAGGCAATGTTGCAGCTTGTATGTAATGTGAAACACTAATCCATTTTTTTTATAGAATTTGGATACATACTTTCACCTACAGTAACGTTTAATTGATTGCCTATTAGTATTACCGCAGCAGTCATATAAAGCCAGAGCATAAGTACAATTACAGTGCCAACTGCACCATATGCTTTATTATAATTGCCAAAATTTGCTACATAAATTCGGAATAAATTTGATACAAATGCCCAACAGATAGCCGCGAATATAGCCCCCGGCATAATTGGCGTACCTTCTTTCCAATTGCTAGGACCATAACGATAAATAAAACCGAAAGCTGAAGCTACAATTACTAATGCTAAAGGCCAACGCATTAGGTTCCACAAATATAATAGAAAATTTAAGTAACCAGCGGAATTATCAACTACAAAATTTAAAAGTTCTCCGCTAATAAATACTAAAAGGCAAGCTATAAGTAAAAGGATAATAGTACCAACTGTTAGTCCTAAAGACACTAATTTAGCTTTCCAAAATGGACGTATATTTGCCGAGGATGTTTGTTGAATTTGATCTAAAGCTGTCATTGCGGTACTAATTGCACCGGAAGAAGTCCAAAGCGCAGCCAAAAAGCTTAACGAAAACAAGCTGCCATTCTTGGAATTAGCAATTTCGTTACGAGCAAATTCAGTAATTAAATTTAAAGCGTCTTCAGGTGCAACTTTACTAATTTGCTGTGCTAAATCCTTAAAAATATTTTGTAAGCCTTCTTCCAATAAACCTATTGCCGTCAAAATAGCTAAAATCGCCGGGAATAAAGATAATATAGCGTTATAAGCAATTTCGGAAGATAAACCTAAGAGTCTTCGTTTACCTACGTTGGTAACAATTTCTTTCAAAACCTTAAAATTAAGATGACGAAAAAATCTCATAAAGCGAGGGTTTATCATGTCGGTTGCTTGATTCTGAATCACCAATTTTTAATTATCACCCTTTGAGTGCAGTTTATAAAGACGGTGCTGAGATTAGAAGATAGATCAAATTAAATATAAAACCTCACCCTGCCTCCGGCTTCCCTCTCCTTATTAAGGAGAGGGATTGAGGGTGAGGTGATTTTCTTATATTTAATTACGTCTACCTAATTAGAAGATGGGTAAGAGGTGTTCACTGTTAACTGCTAACTGTTCGCTGTTCACTGCTCACTGTTAAAATTGCATTTGTCTGCGATTCTTTTCCAATGTCTGGGATTATGCGTTTTTTATTGATTTGCCATTTTAATTCTAGGTAGTCTTTAATTACTTTTGCGCGGGCTTTGTTAGTATCTGTTGCTTCTTCTGGTTTTTGATTGGCGATTATTTTTAAGTTTAAAGCCGGTTGCCCCTTTAGGATAGAGGCAGTTTTATCTAAAGTTTCTAGACTCTGGGGTTTGAGTACTGTTGAGTTTTCTTCAAAGGCAATATTTCCAGGATTTTCAGCAATTCTCTTCATGCTGACTTGTGTTAATGGGTAATTTAATCTTTGTCTAATATCATTGGCAAGTAAAACTTGAGCATCTTTGTCAATTTCCCGCTGGCTTAAATAGAAGATACGGATAGCCATCGAATTATTTGGGCTGGTAATGACTTCGTAATTAATCAACTTTGCGGGTGGTGGCAGTTTTAAATTAAGTAAAGATGATTTGACTTCTTGAAGAAAATCAGATTGCAATTCGGCGATAGTAATTATCGGCTCTGGAGGTTCTTCTTCAGGAATGGCGTTTAAAATATCGCTTTGGGCTGTAGGGATTTCAATTAAGTTTAAAGATAATAATTCTGGAGGTTTATTCAACTGATTGGCTAACAGTTCGATAAAATAGTTTTGCTCTTCTGGCGCATACAGTTCGCTAGTAAAAATATGTAGCTGAATCTTCAACTGTTGATTGACTTTGCGAGTTGAAATTTGATTAATAAAAGAACGCGGTTCGCCATCATTTGAAGTCGAAAATTCCTTTTGCCAGATATTCCTTACTGCCGAAGTTATATTATTTTCCTGTTGTTTAGTAACTATTTCCTGTCTGAGTTGAATAAATGACTGATAGAGTGGAACCAAAATAGTCAAAATCGTCACTATAATCAATAAAAATCTACCGGGAAGACTGCCAATTTGTTTCAAGCGTTTCGATTGCGGAAATAATTCTAAAACCGTTTTTACCCAACCGCTTTCTCTATGCTTTCTTCGCCATTCTCGAATTCTTTGCTTTGCTCTAACGCTATCAAAATATCTTGGGACGTGAGAACCCCTGGTTTATAACCAGGGGATGAAACGGACAGGTAAAGTTTTAACTTTCCGTGTTTCTTTTATTTACTAGTTTGGTTCTCAATATACTTACGAATAACGTCGGTACTTACTTGTCCTGTAGTAGCTACAAAGTAACTAGGACTCCACAAAGTAGGTAATTTTTTTAACTGTGGATATTCCTTCCTTAGAATATTAGATGCTCTACCCTTAACCCACTTTGCAATTTGAGAAGCTGACTCATGTGGCGGTGAGTTGATAAACATATGTACATGATCTGGCATCACTTCAAGAGCGATTAATCTCCAGCCATGTTCTTTTACTAACTCAAAAATAATTTCCTGTAGCCGCATAGCGATTTCATTAACTAATACTGCTTTACGTCTTTTTGGGACAAACACAAAGTGATAATTTATCGATGACACGGATTTTTCAGCCCTTCTGTATTCATAATCTGACGCTGACAACTTAGCCAT

Protein sequences of DBSCAN-SWA_3

>NC_019678|5028608:5109614|5040196_5040697_-|WP_015120037.1|DBSCAN-SWA
MEVILNDITKLEVNAIVNAANTSLLGGSGVDGAIHRAAGKELVMECRSLGGCKTGDAKLTKGYNLPANFIIHTVGPVWQGGNNGEPELLANCYRKSLQIAIERKFESLAFPCISTGIYGYPKDKAAEIAVKTCSEELKNKNSQLKVIFCCFGKDNYQIYQRILNQL
>NC_019678|5028608:5109614|5031343_5032351_+|WP_015120030.1|DBSCAN-SWA
MRTLVVGDIHGCYQELIELLAKAKITESDCLVSLGDIVDRGADSVKVYDFLRNRPNTIVLMGNHERKHLRNTLSYSQEIVKLQFGDRYEEFLEWVSNLPYYHETAEAILVHAAVENGIPIQKQREEVLCGCTAGEKHLSKRYGDTYWSELYTGEKPVIFGHHVVGDNPLIVAGKVYGIDTAACHGARLTGLILPSFEIVQVQAAKDYWREEIPKWQLPVMMAKPWNTYKWDKIKAICSDRDSRNPELSNFMVKKEQWMNNLLALAPQITTKVEEKLAELISLYGADNFKKQARNYSYATLLYKANSSGLDKDFLKQTLRTPSEWLQVMKELGVKS
>NC_019678|5028608:5109614|5064639_5066007_-|WP_015120055.1|DBSCAN-SWA
MAIATINPTTGETLNSFESLNDTQVKDAVSLAHKAFGDYRKTSFGQRSEWMYKAADILEQDKADFAQIMTLEMGKPYKSALAEVSKCALVCRYYADKAAGFLKDVSIETDASHSYVSYQPLGIVLAVMPWNFPFWQVFRFAAPALMAGNVGLLKHASNVPQCALAIEKIIHRAGFPQGVFQSLLISSDKVADIIADERVKAATLTGSEGAGASLAAAAGKHIKKTVLELGGSDPFIVLASADLEAAAVTGTTARMLNNGQSCIAAKRFIVEEAVADKFEKLLLDKFHALKIGDPMQIDTDIGPLATHDILKELDEQVQKSINSGATALLGGKPLLNMKGNYYPPTILTNISPDSATAKEEFFGPVAMLFRVKDIDEAIQLANNTPFGLGASAWTSDTVQQQRLISEIEAGAVFINGLVKSDPRMPFGGTKLSGYGRELSIQGIHEFVNVKTVWVK
>NC_019678|5028608:5109614|5033965_5034736_-|WP_015120033.1|DBSCAN-SWA
MSNMMYADAPTYEAINAAEIDKIRIKHAWITEPIFRASEAVKQMPFFDWVAQIHSPSEFKPVALQLYYHSATFPKVMGLMLGNTPMSENHMMPFYAKHAYGEADHHQMLMDWMLKYNLLNNSQEIEEIIPTPETNACVNLAYQLAIEQDRAKWLVTINSGIERCSNDFFKAVAPKMHELGAGDSYFDIHVEADEHHSIMGMDYIEPVDPQSLRGRQLIAKALEGITLWAAMLHSWVDIEYFPVFNLDGTLKKRKLI
>NC_019678|5028608:5109614|5050972_5051398_+|WP_015120047.1|DBSCAN-SWA
MLKRSLAVAAVGTVLSIGSISPSLAAPRDFVGTWVNTNSNTRGITKLVVRRVSGNRLIVRTYGSCSPRDCDWGRARLTTYGNSVQDRNHRSATTTYNKSFANTLLTINLRGRDRLSLQSFTQFKDNSNRQNYTSRAVFRKR
>NC_019678|5028608:5109614|5030176_5030668_-|WP_015120028.1|DBSCAN-SWA
MKKVLLISSFVGIPILIILGAIVYYIFPNVYPKTYTVDCTQAKKIAKISDVYFPGMGFPAYDKLEPVVERYITKAVCLNDLKGDSSFNPKPYFLKPSDMSHQYQIVGYKGAVFRSPGSLKIEFDNGTLINFCSDVLVINCDRGECRCPHDFNWEPKPKKNNSK
>NC_019678|5028608:5109614|5042654_5043776_-|WP_015120040.1|DBSCAN-SWA
MTAASKNQQGEIGVAVVGTGFGKKVHIPGLKAHPKTQVVAVYNRDLDKAKEIAESNDIPHACDNLTDILQLPEVQAVAISTPPFLHYEMAKQVLQAGKHVLLEKPVTLNVTEAKELYHIAQEKNLAATVDFEFRFVPGWLLFCELLAQNYVGNKRLITINWFGSSRANPDRAWNWYSQKEKGGGALGSLGSHTFDYIHWLFGEVRRVNAHFTTAIPQRPDATTGEMKPVNTDDTCALTLELADGTPCQVSISAVIFAPRTHAIEVYGDEGTLILASENQKDYVHGFRVWGGKAGKPVAEIEIPNRLTFPKNYADGRISGFLRVVDQLVAAINSGESTTPSLREGVYSQLLMDKSHESNETSNWVNVPSLDTLI
>NC_019678|5028608:5109614|5089867_5091298_-|WP_015120070.1|DBSCAN-SWA
MATNNNDFLVGTNGPDLINALAGNDTVIGLRGNDTLRGNAGNDRLFGNENNDSLQGGIGNDNLDGGSGRDTLRGGAGRDTLAGATGNDNLFGNGGNDSLLGGNGNDNLNGGNGRDTLRGGNGRDTLSGGNGNDNLRGGNGNDLLRGGAGRDTLSGNAGNDNLFGNRGNDSLLGGNGNDNLRGGNGNDILRGGAGRDTLSGNAGNDNLFGNGGNDSLLGGNGNDNLRGGNGNDILRGGAGRDTLSGNAGNDNLFGNGGNDSLLGGNGNDNLRGGNGNDILRGGAGRDTLSGNAGNDNLFGNGGNDSLLGGSGNDNLRGGNGNDILRGGAGRDTLSGNAGNDNLFGNGGNDSLLGGNGNDNLRGGNGNDILRGGAGRDTLNGGNGNDRLFGGAGADILIGGAGADTLTGGAGADLFNIQGFDTITDFRFFEGDRFTFGFSSNISDFDIQGNQILFQNQAIASLTTAPSGFEIQDAIMM
>NC_019678|5028608:5109614|5070927_5071818_-|WP_015120059.1|DBSCAN-SWA
MSITHNYKLNIIQWYPGHIAKAERQLKEQLKLVDVVLEVRDARIPSSTHHPQVSEWIGDKARLLIINRLDMISSEARELWTDYFRANNEVPIFTNAKQGKGVNGVAKAAQSAGSQVNERRKEREMLPRPIRAVVIGFPNVGKSALINRLLGKRVVQSAARPGVTRSLRWVRISKELNLLDAPGVIPLKLENQEAALKLAICDDIGEASYDNQKVAAAFVDIVGEMQETAPQILPENPFLLRYKLESTSYTGEEYLFALAEHKYQGDVERSARTILTDYRKGNLGQFPLEVPESIDS
>NC_019678|5028608:5109614|5096976_5097822_+|WP_044292074.1|DBSCAN-SWA
MNNFEQIQNTYKNYRDDYSLEQRKNWYSKVADAYNKTRPRYPQELINRTVELAKLSKNTNILEIGCGPGTATVEFAKLDCPMVCLEPSQDSCNLARQNCESFPNVEIINTTFEEWELQPNKFDTVLAATSFHWVSPEVGYPKLEQALKDNGSLILLWNKEPQPSYEVYQILDEVYQKQVPSLSRYEDRGTTERIIRKLGENIAKSGLFKDLVFECRECDRVYSIDDYLTLLSTLSPYIVLDVQKRDALFDDLRNALSKNLGDTIETSYLSAFHVAWKKGKS
>NC_019678|5028608:5109614|5060387_5060834_-|WP_015120052.1|DBSCAN-SWA
MKKVLFLCTGNYYRSRFAEKLFNDLASQKNLSWEADSRGLALERGVNNIGAISRYAVVALKQRGITITPEERFPKSAITEDFQQFDLVIAVDESEHRSLMQERFPQWLNNIEYWLIHDIDKTSPEEALGELEKKVRDLISQLGVNSEQ
>NC_019678|5028608:5109614|5105289_5106231_-|WP_015120079.1|DBSCAN-SWA
MKNWWQDTFPQGKQTITITDSQGYPVKIAYGEKGKGKPLFLLHGIGSWSYNWRNLIEPLSKYFRVICFDAKGFGFSEKPLHREETTGHQVIELQRIITALCNEPVAILSESLGALVALAFAQEYSELVSHLAVVNVPIFTKKLPHWGMSLLAKTPLEIIEVIDKLRLSYLFAPLIREIMAIERRSVLFDPSILTQENVFWITYPYIEFPGTFLKVAQELQIAAREIENAQKNQPNWLSKIQNNLINIECPTLIMWGEQDTWFPIEHGKQLHQLIPSSLFQVLPECHHDASSGASDAIEIATVDFLRKTNFLQL
>NC_019678|5028608:5109614|5097878_5098952_+|WP_015120075.1|DBSCAN-SWA
MKLQRVQVPDFRVLKNVDISFEKDFVPNIFPLGSQNGGGKSTLLQLIFVLLHCSGDSDKHEFIKNMLHGFEIDDDSQKRVLARFDIWDGEKTVNLEFVVYKDSYARRFLHQNNKPLITISETVFCRIDKMDIDKAKDFLNNLSSNIFLAAPATQVFLFLNKDSRDFLFKHQNNDYSNNYYSQLKQSQYKLSVFFTYDFLAVDLLIDIFQAARDKDFKQAIETGEYGNNYQKLVNDLNQVLLNKKININPDLSGFTFKLDAEGNDIELYPEDLSHGELKRLSIYAWIKYNIIEDSIVLIDEIENGLHPDWQYQIIKDIAEWAPKNQYIIATHSYELCQAVTPAHVKELEPRLIKQESE
>NC_019678|5028608:5109614|5035811_5037833_-|WP_015120034.1|DBSCAN-SWA
MVVPRTRIRNIGISAHIDSGKTTLSERILFYTGRIHAIEEVRGGGKGATMDFDDLEKEHGITISSAATSCQWQDTQINLIDTPGHIDFTIEVERALRVLDGAVMVLCAVAGVQSQSITVDRQMKRYSVPRIAFINKMDRTGANPFKVVEAMHDSLDLNALLLQYPIGAESQFEGVVDLIAMEAHFYEGKNGEIWVKRKIADELKQEAEAAREKMLDTLSLFSEEMTGKLVEGEEVSQELIWKTIREATLNLELVPVLIGSAFKNKGVQNLLDAVSLYLPSPVDKDFVNATVFETGESVNINLNLDAPLVALAFKLTVESFGQLTYIRVYSGILNQGDTIYNSRTGEKVQVGRLLRMHANKREEIKQAVAGDIVALLGVECASGDTFCSSEIRVSLENIFVPEPVITLAIEVNKNQDLDKISKALNRFQKEDPTFRVNVDEESNETLISGMGELHLEIYIERMKREYYLDIAVGKPKVSYREAISQRATFDYKLKKQTSGPGQYAHVVGYIEPCEEQFVFENKVFGGAIPKEYIGGLEKGFLEAMNLGMLEGYPVMGVRIVLENGSHHMVDSSEFAFRMAAQQAFTQAFMKAKPHLLEPIMSVEVETPDEFLGRVQGDLSSRRGLLLGSQTMQGYSIIRAEVPLTQMFGYSGNLRSLTSGMATFSMQFDCYRKA
>NC_019678|5028608:5109614|5046685_5047483_+|WP_015120043.1|DBSCAN-SWA
MFVNTIKSVVFGSMLMLSTASVALAQPSLPAPEFQIKPASKFTCAPHTRTYIVKSLTNAKGKGIRCVKFANGSRRNRLPRIAWYGEGNWSGRTYRHVGQAFYRGRNLIGFASDMHGNGEYFNGNFNGNLKLQFVSGSKIRVTGAWNEEWIPVKSTSYKPLPRPKTCGNYFDQYKVSDLTGKRRGSGLRCVLRVGRKNTTWFGNGNWGRSTYSHIGTRGYKGYGASDICDTPFGPICNKFAFGSLKLTPAGSGFNVTGAWSEKWRK
>NC_019678|5028608:5109614|5029484_5030117_+|WP_015120027.1|DBSCAN-SWA
MPSAQFPIQIIVIAVSPVIRMGLSAMLEDNPKFKVLKSVADIDSLIDDIAQLQPDVVLLDWNSQDYESISQSQQFMSATIILVDEIEDINFATVLAARIKGILPHDSTESEIIAAVEAVASGLVVFHPDIVDNLQLQKPANSQQHETLTNREIEVLQMLTSGLSNKAVAQQLYISEHTVKFHVSSIFQKLNVSTRTEAVAVGVRLGLIML
>NC_019678|5028608:5109614|5050471_5050612_-|WP_015120046.1|DBSCAN-SWA
MTIQALIFYVLLAITGALIIWRIRTNPVTQIRDGVINGDIEKVKQC
>NC_019678|5028608:5109614|5057388_5058618_+|WP_015121012.1|transposase|DBSCAN-SWA
MPDNHKVKIIQDKYDSLSPYLNEKTRRIWAAIEAQSLGWGGVTAVAIATGLSRTTIHSGIDLLSKLDEVKTEDESTRIRTVGGGRKLLEEKDAMLLSDLESLLEPMTLGDPESPIKWTNKSVVKLAAALKEGGHSISPKSVYNLLESLGYSLQSNRKTRDGSSHEDRDDQFLYISNQVKYFQSHNEPVISVDTKKKELIGNFKNPGTEWCDSEQPVEVRMHDFVDPNAGKAIPYGIYDLTLNKGWVNVGIDHDTAEFAVESIRHWWYSMGNLLYPKSEHIMITADSGGSNSYRSRLWKLKLQEFATEIGKSIHVCHFPPGTSKWNKIEHRLFCHITTNWRGRPLTSLQVVINLIGNTTTTQGLVVEARLDENLYQTGIKVTDKELDNIAIERNSFHGEWNYIIKPQISG
>NC_019678|5028608:5109614|5047923_5048337_-|WP_015117596.1|transposase|DBSCAN-SWA
MAKLSASDYEYRRAEKSVSSINYHFVFVPKRRKAVLVNEIAMRLQEIIFELVKEHGWRLIALEVMPDHVHMFINSPPHESASQIAKWVKGRASNILRKEYPQLKKLPTLWSPSYFVATTGQVSTDVIRKYIENQTSK
>NC_019678|5028608:5109614|5083155_5087505_+|WP_015120067.1|DBSCAN-SWA
MQSNAEPIDLPPLTRFINTSPAIVTPETLVIDAIALMRIPVQNINQNLNAPNISQITVTANNQQTDCVLVCENLLLQGILTTSDIIRFILSRNNLNKVKVAEVMTRQVVTLKKSQSNNIFTALQLMRQHRIGNLPIVNDFEQIVGIITQDSLLQNFDLQALLQRQTQTYNCYESHKQVNFETHVLNRLGDAVVGIDNEHCIIYLNQAAEKLYNVKLENFVGKRLEEAYDSRWVNSEDEQAARDALSATEAWQGENIHIKNNGEEIFVESSVNVLKDNSGENIGLIAVIRDITKRKRAEIAIREKLQQLETIVNNNPIGIYRFIYHTDGKVSIPYASVGYRQLLGLNPTDMSAYPEDVLATIHLDDREKFAQALITATGEQHQSHYMEYRAIDVLGQVKWLGNNFRCSNHTNGDLIVDGVDIDITPRKRAEISLQTSEERFRSLVEISSDWVWEVNEYGFFTYASPKVLDILGYTPQEILGKTPLDLLPTEEGKRLVEVLNSFIIEKQQFKNLENIKFHKNGNSVIMETSGVPIFDANGYFRGYRGIDRDITERFQAEDRLRTSEERFRVLVTHAPVGIFQTNAKGECLFVNPRWSEITGLSEQEASGEGWSKALHSDDKEQVFTAWYDAATAGQEFAMEYRFCTPEGKVSWVFGNAIAICNQTGDITGYLGTVTDITEHKQAEEKLRWTQALLQEAQRIAKMGSWSRDLTTNERWWSEQYYRIINLNPGDAMPDVETVINSNVHPDDRDKIYQMVMACIEQGIPYETEVRFLNADNSIGYVFICGRVERDSQGNLCRYYGIVQDISEYKQVELELRESKERYRSVVKSMHEGVVIQQADGTIISCNASAQKILGLSAEQIKGRNSVDPRWRTIHEDGSPFPGETHPAMVALHTGKPCLYTVMGVYKPNGKLTWILINSEPLFLPGQNLPYRVVTSFSDITRRKEAEEKIKEQAQLLDITTDAILVKDLEETILYCNNSAENIYGWKKEELIGKTANEILYEEISPELESALSEVVEAGSWQGELHKITKTGKNIIVASRWTLVRDKTGKPESVLTVDTDITQTKHLENQFLRTQRLESLGTLASGIAHDLNNMLTPILAIAQLLPFKLNNEEQDCREMLSMLEDSAKRGADLVKQILTFARGNEGKRTVLQIKHLLKEIEQFANRTFTKSIAINRYLPQDLLTISADPTQMHQVFMNLVVNARDAMPNGGTITISAQNLYIDESYAKMNIEAKVGNYVVVTIADTGKGISPEAIERVFDPFFTTKEVGKGTGLGLSTAIGIIKNHGGFIEVTSELGKGSQFKVYLPSTQDKRIEPAQENIALLGNSEQILIVDDEPAICEIVKTTLESQNFDILTAADGIEAISTYVQNKTGISIVLIDMMMPEMDGATAIATLQQLNPQVKIIAMSGLTSTQTLAQAAGTGIQGFLAKPFTQYDLLNTISGVLSASSN
>NC_019678|5028608:5109614|5069239_5070748_+|WP_015120058.1|DBSCAN-SWA
MNQDNSTESKTSIFLILVITSVVIVLAATLYPFNFALPDSISKRELVNSFDNNSFFNDQVNNVLLFLPLGFGLTGLLQKRKVKLVWQIFAAFLASAALSSTVELLQILVPSRTPTPADIFNNSFGGFFGLICFYIWNSRSFKAILHRIETSRASNSISKITLFFTGYVILTFLITIPWQATTNLTGWNPSFPLIVGNERTANRGWEGYISQLNIANQAFSQNQVKQLFLPNNSFENLGNSAIAAYEFKGKAPYQDRIGKQPDLLWNGESAIQNEQGVFISSNNWLKTATPVTSLSKSISKASEFTISTTLATNKTEQVGPARIISLSNDSFRRNFTLGQQGSDLVFRLRTPLTGANASDVKLEVPGVFSDIQPHQIVITYSKSSLIIYVDSISNIHTLNLLDLIPKEKRFFYYGITFIPFGLCLALLTTLAKRKINFYRLLLPAGILLPSLILEGILVQESGKSISPKNIFLGILFTAGTMFILKARTGTVISEQSTVNSQQ
>NC_019678|5028608:5109614|5099967_5101704_-|WP_157229437.1|DBSCAN-SWA
MLAFCFAMLTACDASWDRKVKQSQLTLATPSDVATFNYAMNNSPFSVFPFIYQGLVTENGKTNELEPALAESWKVSDDKLRITFKLRDKLKWSDGKPLTVDDVIFTYKDIYLNKKIPTLFKDFLRIGNQDVFPEIRKLDNRTIEFSLPEPFTPFLRKSASLAILPAHALRDSVLSNDANGNPQFLSTWGSDTAPEKIIVNGAYQIESYTPSERIILKRNPYYFRKDAQGQQMPYIKSIIWQIIPSTDNHLLRFRSGELDSLRVKPDTFALLKREEKRGNFSIYNGGLSQGIRFVTFNLNQASNSQGKPFVNPVKSRWFNNLAFRQAIAYAINRDRIKTNIYQGIGELQHSPIAVQSPYYLSPAQGLKTYSYNPQKAKQLLTKAGFQYDSQQQLLDKDGNQVKFNILVKSEDQTRVATAVQIQQDLKQIGIQANLQTLSFNTVLQKILTKRDWDCYVGAFESAIFEPNLIALFWTSNGSFHMFNKGSKSKKRPIIGWKVNDWEKQIDQLFQEGAKEADENKRKQIYAEFQQIVAEQLPVFFLVNPVSLQAVRNRVENVEYSAVGGLLWNVDEWRLKGEG
>NC_019678|5028608:5109614|5051550_5056452_+|WP_015120048.1|DBSCAN-SWA
MSPIGIATSRLNYKNKESAAKLWLLLIGVNQYQDEQIPNLRYSAVDCQGLSSALQDTTDKFSRKEANIYHDSTPRTPCLENIRTSLQKIIVDAKPHDTVLFYFSGHGVLESSTNQAFLCLRDTYKSKLLDTGLAVSELLQSLNNCAAKNQLVWLDACHSGGMTLRGVTPQLVEILQQNAVNSKGFYALLSCDTNQQSWEFPELGHGVFTYFLMRGLLGGAANSQGVISADGLYQYVYYQTLQYVDKTNQQLRLINQQKQAKGNTLLQREYSLQTPKRIVEGVGEIILAKAPPKNALSVNNRVGLVIEGFSDSQETLEISKLLGSVGNFQLEYLQAAKLSAQKLKEIISDRLKTNAAETVLLYLRGSIEETSTWEGLILGENIRIKRSWLKHLLHDIAAKQIVILDCPNFDSNSSNVQEWLEDLQIDSQQGQCLVVSAGSQFSQILLDTLTKTPATTGLSAAGCISQLQLQLAGSDNLKVWLSGTQGIIEIIPGKSEFTSRNQKQAIDLNICPYMGLNAFSPEDARYFCGRENLTQQLIYQVKNNPFVAVVGASGSGKSSLVQAGLIPTLRKGKQIPNSEKWLIKILRPGNNPLETVAATFSFFHPLSPENFVYRLRKIPQTITVLVIDQFEELFTLASVKERVKFLEILLSAVQYASDRFKLIITLRADFVASCLEVTSLTKLLQDSSLLVPPQLNQDNYRQVIVKPAEQVGLKVEPELTEILLRDLDNSVGDLPLLEFVLEQLWQHRHQGELTLKAYEEKLGGIKGALERSSQAVYDNLSPSAQECAKWIFLSLTQLGEGREDTRRRIFKSDLIVKKFHAELVEKTLAAFVAVKLIVVGNEDGEKTELCAKSNSITVEVAHEILIRYWNTLRGWLEENRSRLRLQRQVSQAAQLWKQNGENNDFLLQGVRLAEAEDIYLQYTDELSSNVKQFIEACLQQRKYQQFEEKRRLRRAQRGLVALSILGIASCGFAGLAYLQGREANIREIQALNSSSKANLLSDRQLETLLNSVEAGKQLQKTIAVPSPIRYQTLNALQQIMSKIREKNRFQGHTSWVNSVSFSPDGKIIASASSDNTVKLWRRDGKLVNTLVAHNAGVNSVSFSPDGRFIATAGDDETVKLWDAVGNLLKSFRAHDSGINSINFSKDGEKIISGSNDTKIKIWNRNGKLLNTLSGHLESVNQAIYSEDNQMIVSAGNDNTVKLWSTDGKLLKTLQGHDKDVFSVSFSPNGQIIASTSDDETIKLWSRNGDLLNTVPMGKTIKIWNQNNTLTDTFINHNNQINSISLSPGGNFLATASDDYTVRLWNINSILTNTFFGHTDEVTSVKFTKNGQEINSVSDDGTMKIWRKDGKLLKTLSAPINNVTSFNISPDKKIVFGSDDGILTIWSEDNRLIHTLPAHRGWIININFSPDGKVFASSGIDGTIKLWTRDGKLVKVLNDHNGWVTKVKFSPDGKIIASAGADNTVKIWSRDGKLLHNLTAHTNSVWDINFSPDSNMLASASADKTIKIWQRNGKLIETLNGHADSITSVVFSPDGKAIASSSDDDTVKLWSSKNGQLIKTIKGHNGNVRSVDFSPDGKTLVTASADKTVKLWNLEKVELQPLKLNALLAQGCHWLDDYLKWNSNVSEWDKQVCS
>NC_019678|5028608:5109614|5106920_5107814_-|WP_015120081.1|DBSCAN-SWA
MINPRFMRFFRHLNFKVLKEIVTNVGKRRLLGLSSEIAYNAILSLFPAILAILTAIGLLEEGLQNIFKDLAQQISKVAPEDALNLITEFARNEIANSKNGSLFSLSFLAALWTSSGAISTAMTALDQIQQTSSANIRPFWKAKLVSLGLTVGTIILLLIACLLVFISGELLNFVVDNSAGYLNFLLYLWNLMRWPLALVIVASAFGFIYRYGPSNWKEGTPIMPGAIFAAICWAFVSNLFRIYVANFGNYNKAYGAVGTVIVLMLWLYMTAAVILIGNQLNVTVGESMYPNSIKKMD
>NC_019678|5028608:5109614|5030683_5031256_-|WP_015120029.1|DBSCAN-SWA
MNIESKILIFITITVCIAILAISIYPGALGSLFFALLLVSIICIPIFIVVGIFALIVLGRRGLFSKVNISWRLVRAISGIVLLSCILLQFYIPRRLAFLASKSAFEQIIASGKTASNRQLGLYKIDKYAVDSGGGKYFRVKTIGNGFSPDVTSYGFVYQPNRKASPFGNANYQVFNLYGNWYWFEASNDY
>NC_019678|5028608:5109614|5108034_5109015_-|WP_052330835.1|DBSCAN-SWA
MKQIGSLPGRFLLIIVTILTILVPLYQSFIQLRQEIVTKQQENNITSAVRNIWQKEFSTSNDGEPRSFINQISTRKVNQQLKIQLHIFTSELYAPEEQNYFIELLANQLNKPPELLSLNLIEIPTAQSDILNAIPEEEPPEPIITIAELQSDFLQEVKSSLLNLKLPPPAKLINYEVITSPNNSMAIRIFYLSQREIDKDAQVLLANDIRQRLNYPLTQVSMKRIAENPGNIAFEENSTVLKPQSLETLDKTASILKGQPALNLKIIANQKPEEATDTNKARAKVIKDYLELKWQINKKRIIPDIGKESQTNAILTVSSEQRTVSS
>NC_019678|5028608:5109614|5067038_5068652_-|WP_015120057.1|DBSCAN-SWA
MTELKLRLQRGNTQKTVTVDQDIYVVGRLPECNLCLPFSGISRSHARFAKGENGLWMVEDLGSKNGTILNEQAVIKPTSISHGDVIWVGDISLVVLLTIPPEPPPQSSYTAFSEGRTILRNVKQLQEEWIGADSQEDNTNKKDRTIARLKDLVDIAKNLSGATSIEEIFSQVQQVVFRYLNSIDRLGLLIDVSNCGKLVLINAASRDVNNKQQLMGDDSWISQSICQQVFGEKVAIQSADTHQDERFAEEHSVFLKGIRSAMAVPLWDENKVVGVLYADASFSSYHWIKEGSEDLSFFSTLGNLVSSSVQRWLLVEKLKNEEVIRQRLERYHSPAVVQQLIALGALPDGRLPPQESEISILFADVVGFTAMSERFTPTEIAELLNKLFEEMLQEVFACGGTLDKYIGDCIMAFFGAPEPQKDHADRAVVAAMRMLARLEKLNFNHFWQEPLELRIAINSGKAVVGDVGSSQRVEYTALGATINLAARMEGICHPGECVVSEETHKMLSKPNRFELMGKYRFKGINRLVKVYHNRRRY
>NC_019678|5028608:5109614|5047590_5047842_-|WP_015120044.1|DBSCAN-SWA
MIEIAEFLLKNGLPINARDADGKTPLHHAASKGHLEMAEFLINNGAKVNSITCLGDTPLSEAKEWNHEEMERLLKSHGGRDVI
>NC_019678|5028608:5109614|5058837_5059518_-|WP_015120050.1|DBSCAN-SWA
MNNKLLKPNFGDKQLQTTRLKQTNIIPFTIYLVAFVMLLIAWLQPAVSFSILFRDVFVAASVKPYYGLFSNIGIFLWSATAAILLFCGTVLINVNKNHKYSKFLLSFGSLTLLLALDDFFMLHETVFPVLLKISEKVTFLAYAIITAYCLFKFRKIIFNSYFTIFIIAITFLLLSIIVDQLIPASSYLFKVDDGYFFEDSLKFIGIISWCFYFIKISGEQIISLSK
>NC_019678|5028608:5109614|5081422_5082640_+|WP_015120066.1|DBSCAN-SWA
MNSKLFYVKAQLAKVYIKDAFLKKILPFLFLSSIIFCLLLNSLAPAIAQQPRDEIRGVWMTSNDFNILKSRAKVNDAVGLLRRMNFNTIYPVVWNSGYTKYPSNAARRAGIPFFYRGEEGHDILADLISQAHRQHLIVIPWFEFGFMIPQSSELALNHPDWLTQKQDGSQTTIGVAGENAWLNPFHPQVQKFISELVTEVITQYDADGIQFDDHMSLPREFGYDKYTVALYRQETGNNPPKNADDTDWIRWRADKISEFMIELNHAVKAIKSDAVFSVSPNYYDFAYKLHLQDWLKWVREDIVDELIVQIYRNDLQSFVATINREEMQETQKKIPTAVGIMAGLRNKPVSMQQIQSQVRASRQHGLGVSFFYYESLWNRTQESKQYRKAGFQAMFPAPAFRSAMR
>NC_019678|5028608:5109614|5066214_5066358_+|WP_015120056.1|DBSCAN-SWA
MKRISNEDLQEEVEEVEGKINFDGLYFYFAHFTAMHQYQNRIYTELF
>NC_019678|5028608:5109614|5093493_5094027_-|WP_015120072.1|DBSCAN-SWA
MSDRTHRESHNRQHLQPKEPMFYYFAYGSCMCPVDLKRTMGENTHHYVMGAGVLKGYRLGFYRYSAFRKCGVLDVVKDSKSTVHGVLYRLPLRLSASLDKREDVPRGGYRQEFVDISFRGKTYEKVRTYVVVNKLLQEIAPNDWYFNVVLRGAITCKLPEEYCWNLFNHMHGLQSSQ
>NC_019678|5028608:5109614|5041936_5042485_+|WP_015120039.1|protease|DBSCAN-SWA
MKSVFSWWTTRVTVISTLLILLSGNSTQANDPGACFMTTEDGRTINLGSLCGITPVKPVDTGVYRIDIKRRSGNTPIVDVTFNGKQTFEMIFDTGASGTLITQSMANALQIKPSGTLQASIADGSVIKLKTGQVKSIGVGGAKVNNVRVAIAPNADTGLLGHDFFGNYDVKIRQNTIELYRR
>NC_019678|5028608:5109614|5040738_5041590_-|WP_085977703.1|DBSCAN-SWA
MINMNNQQRKSRLGWSLDERDPKFIESFMPIWEWFYRHYFRVKTDGWENIPPQEQVLIVGSHNGGMATPDMVMMMYDWFRRYGTERLAYGLMHPYIWKINSDIAKLGEKTGAIAAHPKAANAALKRGASVLVYPGGQYDLFRPYNQRYNINFAGNKGFIKLALRQEVPIIPAISVGAHETLIVLGDFYEIIKQLNTMGLPWLYNLDPGVFPIYLGLPWGLAIGPLPNIPFPVQIHTRICKPIIFEKYGREASKDRDYVDECYNLVCTQMQQEMDKLAREVNNK
>NC_019678|5028608:5109614|5056420_5056804_-|WP_015120049.1|DBSCAN-SWA
MKRQILGSTIAVSTILLTAFPGLKNAVKNIASGKIHKVKYQAVKLDNSMDAMLNPEQGGIRPMPPPPRWIPPVEEGINHQLPPARMPKKPGYGNYTPTRYLPHSTPGRNPLIKDKLQLRNKPAYPIR
>NC_019678|5028608:5109614|5048406_5049819_+|WP_015117597.1|transposase|DBSCAN-SWA
MYKTVPIKAKFTDEEKAFWVDQCEHSNSLYNSAIYLARQNHYAMLLERKANTTYWCGDELRSGWKTYRLETNYYHLDKQLKTCIHYFSLAAQAAQQTLKLVGESITSYNKLVDKYYLGDGSRPSIPKYRKSGGLFAVTFPKQALACHNGYIYPSISKATKPELITSIKLILPEFISFDWIKEVIIRPSRGEFWVDWVIDDGKQPIINNKSLNYNHAISIDHGVKFWLSAVTTLGKSFIVESPQLKTALHKYRNQVQQHKKNKPSRYWDNYLDRITAKRNLQVRDAVNKAARFIINKCLKDGIGNLVIGWNEGNKTNINIGRNNNYEVVSMPTKRLIERLRQLCEEYGIRFHITTEEYTSKASFIDNDELHQYGAKPIEWKPSGKRISRDVYRTKDGLLIHADLNAASNILRKVADQIFINSGIAKLAFEIIKRGALTHPKRYDIFSNLKRSYRKQTMSRSMSLDYGVTTA
>NC_019678|5028608:5109614|5028608_5029469_+|WP_044291055.1|protease|DBSCAN-SWA
MSITFPNLSTELEDVAEKISQSSVKIRHGNIGIGSGVVWKSDGLIITNAHVAVSEKLTVELCDGREFQAVRTKIDPTKDLAALKIDADCANVNLNPATISDRKNLRVGEIVLAVGNPLGDTNAVTTGIISQIHQNSVISDIQLYPGNSGGAMTDSSGNIIGINTMIAYGLAVAISSQTVERFLTTVNDNDKPRKLGVTLKPLIIGTSKQPTLGLLVLSVNRHSYAEASGIQIGDILIGVSGRLFRQLDDLTNYLQVGNHSELQIIRGGKQINLNLDFDNYKTTSEV
>NC_019678|5028608:5109614|5044023_5045202_-|WP_015120041.1|DBSCAN-SWA
MNNISLFTFTSPTDLILEIPLNVQNQAWDKSRNYSNSANCYQAYMNKLCLLAVLPWLESEFAQQAKLSPSTTALPSLWELVNGCSITLSDGTKFVLVPNEDIDLSELQVPQEWVDIPSFVGDYYLGIQVQPDEGFVRVWGYSTHAQLKINSSYDAVFRNYSLDRTDVTTDLSVLTVSKEFCPQEITRSQIPPLANLTSQQAQNLILRLGNPEILNPRLEIPFTIWGAFIEQLGYRNSLYEKRLGLPQQWHVIDWLQNGVSQIAEQFGWRSFNLETSMAGARNLEEIEKSGKILSRQLTIAGKQYILSIIPKNELEGIIWRFQLRNAAAGGFIPGGFKLRLLTEDLQAFPNNEDITATAVEELFVEVMLQPGEGIVWEIEPLPEDYDREVLRF
>NC_019678|5028608:5109614|5038946_5039927_+|WP_015120036.1|DBSCAN-SWA
MENQELSLIPRINCVPRSFDSNAPVNFYTPPFITKSGMQNVFNHFVNRDSDIYVATYPKSGTTWTISIIEHLINKVPPKGISTGASTAEACLWLDRAASVENWRSTFSQLEKMKSPRFFKSHASVGLIKQPARIIQCIRHPLDTFVSAWHHTRGKKHLFYYNGSWSHFFSEIVLQSKYEGGDWFDYHEEFLQASKAGKIDALFLRYEDMKKDNAISAIHKLAEFIGVESYDAEEISRATDFKSMKQKSITEGHIDTEGELSDVLVSREVGDKNNPSKAHIRKGMVGDWVNYLSDDELVMWRDYVNKKKDYCPHVVDFFSLDDLLCN
>NC_019678|5028608:5109614|5092066_5093053_-|WP_015120071.1|DBSCAN-SWA
MTTKKSLLAGGILLTIIGSGLQPVFNRAFAQTTQPQTPLENQLSPQPETKSQIRLITPGAQPRQRLRFVPQTGQKETADMQMDMNMSMSVNGNEAPSFKIPGTSLKLNTTVNKVEQNGDIYYDFSYDNVDIVGESNLPPSALEDMRREIKKMQGLKGNVIVDNKGQTKKANFIVPKNFNPALKQTMDQLKNSIEQLSAQVPTEAVGKGAKWKVTSNISFNGITLVQTANYELVDIQDGIATMNINLTQKAPGAQKIALPQIPKGMTMIMESYNANGTGQSKIALNRLMPLSTSLKMNANTQMRTTVPNSPETMIMNQQISTQLNIQSK
>NC_019678|5028608:5109614|5087629_5088763_-|WP_015120068.1|DBSCAN-SWA
MTSTKVFSGFQKHIPIMGDISLKDPIAYKSTRLMAGILNQAHMVSAEAYINGLEIPDSAFRLLLHASMPIFFKYCPALLAPYEWVLNESDSLAKSSKQLMKLQYDLPQTMLNQMLGDWEVIYPKYSMGLWEDGARNLEESQMHAIDLIIERLEIADGDHILDLGCGWGCVANYIMSKFPNVRFTGLNFSYQQCEYIRRKMQDSQSYLSSGRFTLYEDDLNRVEFVEKFDKILSVGLFEHVGNLTNSLQKVASFLKSDGKAFIHIITVRIPNNMSSGFTHKYIFPHGRYWNYNAIPNHNRDLKTVSQWYINGINYHQTLKAWLQRFDNYQDTIKSLDYGMNYDKFRRMWRFYLLMLGTIFATCDGEYNGNGQYLLVKV
>NC_019678|5028608:5109614|5033320_5033728_+|WP_015120032.1|DBSCAN-SWA
MREKLRLSLSEIAKEDVTQNEREAIIELMMMVMYSDKTLKLTEDEAIKEYASSIEWESPLSLEFYFAKVTPKIRTALSNDEKMHVFLKDINSRIETEVVKAQVLLVCNDLAMADAEFSAEEKDLLKNISQVFQIN
>NC_019678|5028608:5109614|5060969_5061875_-|WP_015120053.1|DBSCAN-SWA
MDEKRLQIYFNIINQLLTNATGEEEEIALDTEPEYIDAGLVQTMIEVAQGLSEEGNEDAAEFLINIANQLAEALGLSLSDFKADNQGELLIQALLITEETEGNPEAVYPLLHKNINFLDATFAEFLRNWAMDAISESTTEEAEDITATIGIFSSLIQEFPLGQRANNLEIAIAGYEVVNCVFTASNYPEQWAATQYNLGNAYADRVSGQKAENIEKAIVCYQNGLQHHTRETYPYEWAMIQNNLGTAYSNRLKEDRTENLDKAIHHYQAALQVHTREEHPDEWQMAQNNLAAIYHHKGKKM
>NC_019678|5028608:5109614|5071890_5072277_-|WP_015120060.1|DBSCAN-SWA
MFFQCAEAFVTIATNNFSELVDFYIQFLSQKPSNYIPNVYAQFQLSGLKIAIFKPKESHLAEFNDSFKSSMSLCLEVKDLETVMSHLENLGHPPFHEITNASHGREVYAYDIDGNRIILHQSHAKGKF
>NC_019678|5028608:5109614|5106319_5106826_-|WP_015120080.1|DBSCAN-SWA
MSLPPSQFYSLNPDVKAPTLKRLRALSRILDKAITIPGTGIGIGLDPILGLLPAGGDFLGVLLSAYIVLEAARLGASQATLGRMTMNIIIDALIGVVPILGDFFDFAWKANDHNIKLLEEHLKFPSQKKRADTWFVFVLIAVLLLLAIGLVTFSVVVSRFVWGLITGS
>NC_019678|5028608:5109614|5098957_5099923_+|WP_015120076.1|DBSCAN-SWA
MSLNSEELQQHCQEIIKQRRIKNKIVILCEGEIRKNQGRPSPQSYKKMEQMPDANFYHACVPSSWRQYRPQFFNCGDRKDVIDTYFNILKLHSKDTNNSYLSPEKLFAIVDLDIQIKKITTEYDYKFSDTEAAFTHLYDKGKVNQENIAEHRIWVTGLIHKEAYFLTPELQEMFDISLNTPIYEGNKLCLEKIYLKMADDIINDVDLQSHIAQASNRIDYCNGLDCSGVEELCNSWKSEFKACNDELRKHELIYSLLTLKKAKYYWNQIQAPEHWNSSIEAFKDQLLLKIGKFYSENSTNPRYHISFLLENLSISNITKPL
>NC_019678|5028608:5109614|5076789_5077872_+|WP_015120062.1|DBSCAN-SWA
MTSISSVPDFIESLLGNEAKDLLTHKAKVSKDMLHLPGSDFVDRIWASSDRNPHVLRSLQSLYSTGRLANTGYLSILPVDQGIEHSAGASFAPNPMYFDPENIVKLGIEGGCNAVASTLGVLGIVSRKYAHKIPFIVKINHNELLNVPNDYDQVMFGDVEQAWNLGAVAVGATIYFGSENSTRQIQEVSRAFKRAHELGMATILWCYLRNNAFKQDKDYHLSADLSSQANHLGVTIEADIIKQKMPENNNGYGAVAKAIGKSYGKTHEKVYSELSTDHPIDLTRYQVLNCYCGRAGLINSGGAAGENDFAAAVRTAIINKRAGGTGLISGRKAFQRPFEDGVKLFHMIQDVYLSEDVTIA
>NC_019678|5028608:5109614|5062846_5064490_-|WP_015120054.1|DBSCAN-SWA
MDTAELLVKCLENEGVQYVFGLPGEENLHVLEALKKSSIQFITTRHEQGAAFMADVYGRLTGKAGVCLSTLGPGATNLMTGVADANLDGAPLVAITGQVGTDRMHIESHQYLDLVAMFAPVTKWNKQIVRPSITPEIVRKAFKRAQREKPGAVHIDLPENIAAMPVEGKPLGKDNVEKSFASFATIRAAAAAISQATNPIILVGNGAIRAKASDAVTQFATELNIPVANTFMGKGIIPYTHPLALWTVGLQQRDFSICGFDNTDLVIAIGYDLIEFSPKKWNPNGEIPIIHIASKLAEIDSSYIPEVEVVGDITDSLNEILKVANRHDKAAPYAIKLRENIRADYENYADDDAFPMKPQKLIYDLRQVMGPEDIVISDVGAHKMWIARHYHCHSPNTCLISNGFAAMGIAIPGALAAKLVHPNRKVVAVSGDGGFMMNCQELETALRVGTPFVTLIFNDGGYGLIEWKQENQFGEGKASFIKFGNPDFVKFAESMGLKGYRVEAATDFVPMLKEALAQDVPAVIDCRVDYRENMRFTKKAGALNCAV
>NC_019678|5028608:5109614|5094161_5096648_-|WP_157229303.1|DBSCAN-SWA
MTSSQGNYTTNRTQIFAALLLTGIVSVASEFTLLKSAIATPVVVPTSQNYKLGNTENNRVVSQRQNNSQTTIQVQRQNSSRSGLPLTVVNAVIKDVSRNQNIPQTQLRVVGYSKETWRNGCLEVLKPGEMCTQALVPGYRVTVSDRNQRWVYHTDNNGRKLRLASGGNSNDSGSQLPASVKSRAIADAARRLQQPVSSFFIMQAQQKTWKDGCLELRDANTICSQVLVPGWRVIVGTKGQSLVYHTNRSGSVVKLNVKASEITDNGLPSQVKETVLKAASKLTASSRVKVTKAEQVTFTDSCLNLGGAAESCLRANQRGWRVTVKGARQTLVYHTSIDGNQIRLNAAASKLRLPRRVRNSVLKEARNISGLSGRKLGIVSFKPANWAYGCEDFSFNNPCDRVAVSGWEVAVSGDSQTWVFFTDATGNQVKLSNQNSQQTQLPRIVANSILKDASKWSGLPSRRIQIVGSQRKIWNNPCFLTFNRICNKALIRTPGWIVTLKANNQTWIYHANDNASIVALDRTPSLTQRAAGVIKQDAARLSQRASSAYQIRVIEVERLNERKDNVPLMKATLSDGRETWTYRFKQDGSEFQLDGTVSLPKSIENGVLADARERLQGRVRVSPENIVEAEKVTWRNGCLGIVSQRRQRYCFYRLVEGYRVTVKVGSETLVYHTDSRSRVILNETVSTINNNPTTVLPVRIPRGELPSPLTRGIVFRQITSGGFAGQTYETILFEDGRIMRYRIGDMNDSSRNLRQVSRKQVSDFQRLLQRQRDEFRNMSYPVARGAADYMVYTLTSRNGTVQFNDTSRQNLPKDLLTVVESWNRILRS
>NC_019678|5028608:5109614|5072914_5076442_+|WP_015120061.1|DBSCAN-SWA
MTSIKDINEPKRVDYQYQVGGSLENDADCYVVRQADEELYQALKSGEFCYVFNSRQMGKSSIMVRSSHKLSKEGYQCTTVDMSCVGSEQVTHAQWYKGVVAELWRGFHLFGKFNLKSWWREEEDISVLQRLSHFIEDVLLVQFPEDKIIIFIDEIDSILSLDFPVDDLFALIRFCYNQRALNPEYHRLTFAIFGVATPSDLIADKNRTPFNVGKLINLGGFTLDRAQPLLKGLEDKVSHSEAILEQILAWTNGQPFLTQKLCKMVRNAEWIIAKSENEARIEVDKLVVTQIIHNWESQDEPEHLKTIRDRILQQQKAGRLLGIYQQILQGIEVEADISREQMELFLSGLIIKENNLLKIKNPIYAEVFDLKWVSLKLSQLRPYSQAFDAWVASNKTDTSRLLRGQALKDAKKWTLGKSLSDLDYLYLTASQELDNYETQEHLEAQRLKAVEARLKAEEKSAARLNSLLFSVSSALIAVSTLAAITFVAYRQAKLNEIKAIATSSRALFVLEKRLDALVQGLKANKKAKQFGKTDSQTAREVTTALRKAIFTAIEYNRITGIDSQIWGVDFSPDGKIIATANRDNTVTLWTRSGTKSKPLTGHKNALRTVAFSPNGKFIASAGRDKVIKIWNRKGDLLKTLEGHQNVVSSVAWSPDSKTIASGSYDKTVKVWDVDDGKFKLSFKAHQNLINAVNFSPDGKNIASASVDRTIKLWDTEGKLIRIYKGHIDEIYSIDFSPDGKKLVSGSMDNTVKLWQVEDGKLIDTFRNHVSGIWKVRFSPDGKTIASASWDNTIKLWNINGILLETLKGHNGRVRGLAWNPNGQTLASTSEDKTIRFWNLNNTLVKTLYGHKNGIIKVAISPDGQTIASVSDDSTIKLWNRNGELLQSILSNSRGFLDVNFSPDNKIIASAGNDNVIKLWTTEGKELSVLKGHNAPVWSVVFSPDGKIIISGSEDGTVKLWNIDGTLIDTINTGQGIIRAVAFSPDGKMIASGGKNKTIKLWNLQGKPLNTLKGHFDTVVAIAFSPDGKMIASASLDKNIKLWKRNGELISTLRGHNTDTRGVAFISTPINSSNINKQNSKNYIIASASGDSTIKLWNTNGKLITALQGHKGAVWDVEFTPDGKTLVSGSEDKTLMLWNLEKVIDSDKVLTYACDLVRDYLQNSADVDSVDRNLCD
>NC_019678|5028608:5109614|5049739_5050393_-|WP_015120045.1|DBSCAN-SWA
MAEFLVNNGANINQGLNEENGSNPLLEAATNNHTELVEFFLARGAVVGIHFAAFRGDIDAVEKFIKQNVQINSTRRGGTPLNLAVMGNHKEIVSLLLDNGADISLYSGGGRPLDCAIRYNHLEIAELLIERGAYINHDSGSHPLRLAICQNKIQIVELLTRKGINFNSLDSLHLAASKGYLTSPSFEKNWDSKQLSLRSLKTYCVTLFACDKTFLDY
>NC_019678|5028608:5109614|5045303_5046479_-|WP_015120042.1|DBSCAN-SWA
MQSRNNLVEIFSTFLQFDADRFRGWVTDGKLRRSMSNRLEKKQAETSDNFWALYWYKMWRISPQPIAQEHLLAYLQESCYWSSLKAANTFANIQYNLSDCFQVAIAKFDKVLKGFNLNSGYRLKNYASAAFGSIIRDTLRQRHEVDICSVWSLLRKTSQKRLIESLQESGLPKDTIANYVLVWNCFKTLYVPTQSNSTRQLPRPDDTIWLAIAQTYEKQTNTVIDSSTVETWLLNCATSIRKYLYPTVTSINAPVGEDSFEWVDNIAANEESLLNEIIAAEEEQKKVSQQSEINTVLISAITQLDIQNQQILQLYYAEGLTQQQIAKQLEVKQYTVSRRLSKTKETLLRSFAKWSQEKLHISLTSDILKTTSTVMEEWLQSYYSEQLTVNS
>NC_019678|5028608:5109614|5032531_5033173_+|WP_015120031.1|DBSCAN-SWA
MLIRIFLVSLISLILVSCQSKEQEKPINNLVTPNQSEKPNSQDSKIATGNTNPLNHSGNFMTLTPTGQTNALDNPLYKISLYVDGKFVDSLIGVSGRKFTQTRNRHQSGTEAPLPDGKYTVATSTIPGAIAEAGEHFLAIQPKFKTGRSALGFHVDPSFEKNNGEDGTAGCIGLTNKEDLDKLLSYVASYQPKFLDVKILDNTNGNLASKGEG
>NC_019678|5028608:5109614|5038215_5038821_+|WP_015120035.1|DBSCAN-SWA
MTGQINDSLIYQGRDFSIVAVDGRELFNPQQYGITPGVGTTACGRGYYCSYEITDNSLQLKQLIVSIYSEPLDRIRIKHGKKEMQNLFGIVPSTKPNSISQIVSSHCATYNEVYAPIKFTGNLLIARDFIRSLYVHMGFQAAYKYKEVYELVFDKGFLNQSINRSEEMAIIRDKIILLSEKSDNWKLDINWKLVWKGKNRI
>NC_019678|5028608:5109614|5109200_5109614_-|WP_015117596.1|transposase|DBSCAN-SWA
MAKLSASDYEYRRAEKSVSSINYHFVFVPKRRKAVLVNEIAMRLQEIIFELVKEHGWRLIALEVMPDHVHMFINSPPHESASQIAKWVKGRASNILRKEYPQLKKLPTLWSPSYFVATTGQVSTDVIRKYIENQTSK
>NC_019678|5028608:5109614|5101885_5105020_-|WP_157229304.1|DBSCAN-SWA
MVFAYSTTDARAQNITLDGSLGTPKTLTGPNYQIPQSVGETAGNNLFHSFGKFNLNRNEAAIFESAGNIRNILSRVTGGSPSSIDGLIRTLGSDVNFFLINPSGIIFGENARLDVNGSFVASTANAIQFGEQGFFSATNLQPPSQLLTINPSALFFNQLQPGKIESKSNLRVPNNRSFLLVGGDINLDGGGLSALGGRLELAGLAGNGTVGLNVDGNDLSLNVPDDVARADVSLTNGAIIDVSAGGGGSITVNARNLEVREESQLLAGIREGLGTPEAQAGDITINATDTVLLDNDSNAFNDVNSGAVGNGGDILVTTDSLQVTNGSGLTSNIVRQGQGNGGSIIITTGSLQVLSGGFLGVSTKGTGDADSIIINATGKVIFDGERKNGIPSVAVSDVEPGAVGNAGGVSITTGSLEVTNGAQLSASTFGKGDAGTVTINATNSIKFDGETKDRFSSGARSNVEFGAEGKAGGVSITTGFLEVTNGAELSASTFGKGNAGNVAIKAADSIKFDGETKNGSLGSGAFSQVNSGAVGNAGGVFITTGSLEVTSGAQLSASTFAKGNAGGVNINATSIKFDGEGKDRVSSGVFSKVDLEAVGNAGSISITTGSLEVTNGAELSAATFGKGDAGSVTINATSKVKFDGQGKDGNRDKSQALSTVESGAVGKAGGISITTGFLEVTNGAEINASTSSSGEAGDITLNVSENITLSGSETGIFASTLENSTGKGGSIIIDPKIMTIRDGARIAVDSQGKGIGGDIELAAGFLTLDNGTISAETRSNTGGDITLNLQDVLLLRNGSQITSTAGNQQFGGDGGNISIDVPNGFVVAVPNENSDITANAFSGSGGGVSINATSILGIAPLTRNKLIERLATNNPEELNPNNLSSSDITAVSQQSPDLSREPVINTPDVDPASGLVELPTNLVDASQEIDQACTPRGRLLQSSFIATGRGGLPLSPNEPLIGQAVITKWVDLQSQITPRRIGKLSRQSTTKYTRKIVEAQKFLVDENGDTFLVAESKQGGDSHSSTSPNQNCRVREGKQERGVE
>NC_019678|5028608:5109614|5078581_5079859_+|WP_015120063.1|DBSCAN-SWA
MTNQFPNRSLQVRVRLVNLFKKYRRLLKRCLPLVFAISFSTVLLLDNLQSTAQLPPPATIIQPEIFQPRQLPRQEIRGVWMSTNDFNVLKTRSGAKDAITQLRRLNFNTIYPVVWNSGYTKFPSITAKRAGIPFFFKGADGQDILADLISQSHRQGLLVLPWFEFGFMTPETSELALNHPEWLTQKRDGSRTSNSAAGEVAWLNPFHPQVQQFIQNLVLEVVSRYDVDGIQFDDHMSLPRDFGYDKYTVALYTQETENPPPANPADEAWVKWRADKITAFMAQLNQAVKARKPYVIFSVSPNYYNHAYKLQLQDWLNWVRLSIVDELVMQVYRNDLASFTRKINLPEIIETKRYIPTGIGIMAGLRNRPVSMRQIKSQVRAAQQRGLGVTFFYYESLWNYAQESVELRQSGFKSLFPRFARRSRI
>NC_019678|5028608:5109614|5079977_5080268_-|WP_015120064.1|DBSCAN-SWA
MKNNLFAIKILSTVLMIGAMGLEIWNIYAITHQLQIPSNIKPIFWIERVAVAAHLFEAIIAAFKAGSKDKIWYKYGIYTFFVGTVGLMELFQEEKN
>NC_019678|5028608:5109614|5059809_5060169_-|WP_015120051.1|DBSCAN-SWA
MLQKIKGFLFIGVGYMLSPLSWWNDLFFNLPIAYLFGYLVSWISPDLFIPFTIIGYWISNILGIIMMQIGATDVFFENKQKNFKKDLLIGLGSSTLYTLLILGLVYFHILQIPSFLNEI
>NC_019678|5028608:5109614|5080414_5080957_-|WP_015120065.1|DBSCAN-SWA
MTNTALITNIFKPNTSPNLFSQTGWAVLRAVVGIMMIHNGLDKLGNIESFAEAYVKVIGLPFPIFFSYVAAFTELFGAPLLILGLLTRPAAFGLFSTMCVAMYHHVLVAGFNISYLELSAIYAACFLFFTINGAGLFSTDALIANWLDKTALSMQAKQIMRLEKAYEASSSEEKAKVAIK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044291055.1|5028608_5029469_+|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_015120027.1|5029484_5030117_+	response regulator transcription factor	NA	NA	NA	NA
WP_015120028.1|5030176_5030668_-	hypothetical protein	NA	NA	NA	NA
WP_015120029.1|5030683_5031256_-	hypothetical protein	NA	NA	NA	NA
WP_015120030.1|5031343_5032351_+	hypothetical protein	A0A088CPU5	Enterobacteria_phage	1.2e-06	28.8
WP_015120031.1|5032531_5033173_+	L,D-transpeptidase	NA	NA	NA	NA
WP_015120032.1|5033320_5033728_+	hypothetical protein	NA	NA	NA	NA
WP_015120033.1|5033965_5034736_-	iron-containing redox enzyme family protein	NA	NA	NA	NA
WP_015120034.1|5035811_5037833_-	elongation factor G	A0A2K5B2A5	Erysipelothrix_phage	5.9e-58	27.7
WP_015120035.1|5038215_5038821_+	hypothetical protein	NA	NA	NA	NA
WP_015120036.1|5038946_5039927_+	sulfotransferase domain-containing protein	NA	NA	NA	NA
WP_015120037.1|5040196_5040697_-	O-acetyl-ADP-ribose deacetylase	A0A0K1L687	Scale_drop_disease_virus	2.7e-36	48.2
WP_085977703.1|5040738_5041590_-	acyltransferase family protein	NA	NA	NA	NA
WP_015120039.1|5041936_5042485_+|protease	aspartyl protease	NA	NA	NA	NA
WP_015120040.1|5042654_5043776_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_015120041.1|5044023_5045202_-	DUF1822 family protein	NA	NA	NA	NA
WP_015120042.1|5045303_5046479_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_015120043.1|5046685_5047483_+	hypothetical protein	NA	NA	NA	NA
WP_015120044.1|5047590_5047842_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_015117596.1|5047923_5048337_-|transposase	IS200/IS605 family transposase	A0A1L2BWN1	Bacteriophage	2.4e-38	56.9
WP_015117597.1|5048406_5049819_+|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1L2BWW3	Bacteriophage	4.4e-60	39.9
WP_015120045.1|5049739_5050393_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_015120046.1|5050471_5050612_-	hypothetical protein	NA	NA	NA	NA
WP_015120047.1|5050972_5051398_+	hypothetical protein	NA	NA	NA	NA
WP_015120048.1|5051550_5056452_+	hypothetical protein	NA	NA	NA	NA
WP_015120049.1|5056420_5056804_-	hypothetical protein	NA	NA	NA	NA
WP_015121012.1|5057388_5058618_+|transposase	ISAzo13-like element ISRisp1 family transposase	NA	NA	NA	NA
WP_015120050.1|5058837_5059518_-	hypothetical protein	NA	NA	NA	NA
WP_015120051.1|5059809_5060169_-	hypothetical protein	NA	NA	NA	NA
WP_015120052.1|5060387_5060834_-	low molecular weight phosphatase family protein	NA	NA	NA	NA
WP_015120053.1|5060969_5061875_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_015120054.1|5062846_5064490_-	acetolactate synthase large subunit	NA	NA	NA	NA
WP_015120055.1|5064639_5066007_-	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_015120056.1|5066214_5066358_+	hypothetical protein	NA	NA	NA	NA
WP_015120057.1|5067038_5068652_-	FHA domain-containing protein	A0A1B1IWY2	uncultured_Mediterranean_phage	3.6e-26	29.9
WP_015120058.1|5069239_5070748_+	VanZ like family protein	NA	NA	NA	NA
WP_015120059.1|5070927_5071818_-	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_015120060.1|5071890_5072277_-	glyoxalase/bleomycin resistance/dioxygenase family protein	NA	NA	NA	NA
WP_015120061.1|5072914_5076442_+	hypothetical protein	NA	NA	NA	NA
WP_015120062.1|5076789_5077872_+	class I fructose-bisphosphate aldolase	NA	NA	NA	NA
WP_015120063.1|5078581_5079859_+	glycoside hydrolase family 10 protein	NA	NA	NA	NA
WP_015120064.1|5079977_5080268_-	hypothetical protein	NA	NA	NA	NA
WP_015120065.1|5080414_5080957_-	DoxX family protein	M4QFW9	Prochlorococcus_phage	7.7e-21	45.0
WP_015120066.1|5081422_5082640_+	glycoside hydrolase family 10 protein	NA	NA	NA	NA
WP_015120067.1|5083155_5087505_+	PAS domain S-box protein	NA	NA	NA	NA
WP_015120068.1|5087629_5088763_-	methyltransferase domain-containing protein	A0A2I2L5L3	Orpheovirus	4.2e-21	28.0
WP_015120070.1|5089867_5091298_-	calcium-binding protein	NA	NA	NA	NA
WP_015120071.1|5092066_5093053_-	hypothetical protein	NA	NA	NA	NA
WP_015120072.1|5093493_5094027_-	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_157229303.1|5094161_5096648_-	hypothetical protein	NA	NA	NA	NA
WP_044292074.1|5096976_5097822_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_015120075.1|5097878_5098952_+	AAA family ATPase	NA	NA	NA	NA
WP_015120076.1|5098957_5099923_+	hypothetical protein	NA	NA	NA	NA
WP_157229437.1|5099967_5101704_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_157229304.1|5101885_5105020_-	filamentous hemagglutinin N-terminal domain-containing protein	NA	NA	NA	NA
WP_015120079.1|5105289_5106231_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_015120080.1|5106319_5106826_-	DUF4112 domain-containing protein	NA	NA	NA	NA
WP_015120081.1|5106920_5107814_-	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
WP_052330835.1|5108034_5109015_-	hypothetical protein	NA	NA	NA	NA
WP_015117596.1|5109200_5109614_-|transposase	IS200/IS605 family transposase	A0A1L2BWN1	Bacteriophage	2.4e-38	56.9

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NC_019678|6504720:6556934|DBSCAN-SWA
TTCATGAGCCTATCAAGTCCAAATACATTTGTCTTCTGATGCTGCTCATGGACAATATATCAGCTTCTCGCCATCCGTAAAACCGCGCCAGAGTATGTACTTCTTGCAACAATCGTTTTGCCCGAGCCGTGAGTTCCGTCCAGAAAAATGACACAATATCAAACAGCAACTGCCAAGAATGTTGGCAAGCCGGACAACTTAGGTTTAGGAGTATTTCCGCTTGAGGATCGCATTCAGCCATTTGTTGCACAAGTTGATTGATAACCGTTGCAGACAAGTCATCATAATCAAGGGAATTACCGCTTTGACTAGCTTGGAGAATGCAGCATTGCATTAGCACAGAATTAGCTTTATTAACATCCTTATAGCCCACAATGGCAGCTAAATCTTTGCTATTTGGTAAGCGAAATTGTAATTCCACCCCTTCCACCTGCAAGTTATATTTTTCAACTTTGGGTGACAAGATTTCAGCAACGCGGATATCCGGGATGTTGATATCAAATTCTAGGCGATCGCCACAATTTGGACATTCAGCCAAGCCATTCATTTTCTGCCCAAAGGTAATTTCTCTAAGGGTTAGTAAATAAGCATCCCGCTGTCCAATACTCAAACATGCGAGCTGCGGTGGAGAAATTTCCGGACAAGCAAAAGCAAGTAAAGTCAACGCTCTATCCAAAGGATGCTGACTTTGTCCGATTTCCCAAATTCTTAAAATCTGCTGGGCTGATAAAGGACGCATAGTGTTAGTAGTTAGTGGTTAGTGGTTAGGAGTTAGAAATTATCTTCCCCCTCTCCCCACTCTTCCCCCTCTACCCCCTCTCCTTGTTAAGGAGAGGGTTGGGGTGAGGTTCCTAAGCCGCTGGATCTTCGTAACTTGGCTCACTTGGTTCAACTACAGATTCATCCCTAACCCAACCGTCGTTTTGCAAAGTAATTGACTGAATCGCCACCGCATTAGCACTAGCATCAAGTTCGGGTAGAGCCTGATATTCCGATACCCAACAACCGAAAACATTATATGAAATAACTTTTTGACCGGCTTCATTATAAACATCAATAATGATGTCTTTGCGAAAGTCAGCTAATGATACTTCCTGAGTGCGTGAATCTGCTGGAGCTTGAGCGTTATTAAAACTCCATACTTTATTTGCCCATTTCTCGAAATCCAAGTCGTGAGTAACTCCCCTTTCTAAGGTAATGGGTTCGTACTTGGATTGTCCGGGGGATGTACGTACCGTACTGGGGTCTCCTCCTACCCGATGTTCCACAACTTCAGTGGTTCGTTTGAGCATTCCCACTTTACTAATACCAGCTACATATTTACCATCCCACTTCACCCGGAATTTGAAGTTTTTATAGGGGTCAAAGCGGTTGGCATTAACGCTAAACTGTGCCATTATTTACTCCTTAAGTTGCAATATTACCAGCGATTTGTTGGAATTTTATGATCACAAACTCCGCAGGTTTGAGGGGTGCATAACCGACAATAATATTAACGATGCCTCGATCTATATCATTTTGAGTGGTAGTGTCTTTGTCGCATTTCACAAAATAAGCTTCCTTGGGGCTGCTGCCTTGGAATGCCCCTTGACGGAAGAGATTGTTCATAAAAGCGCCAATATTTAACCTAATTTGCGCCCATAAAGGTTCATCATTGGGTTCAAATACCACCCACTGAGTGCCGCGATAAAGACTTTCTTCCATAAATAATGCCAAACGTCGCACCGGTACGTATTTCCATTCCGAAGCAAGTTGATCTGCACCTGCGAGAGTTCTGGCTCCCCAAACTACATTGCCATATACGGGGAAACTACGAATACAATTTAAACCCAATGGATTTAGAATACCGTTTTCGAGATCGGTCATTTTATAAGCAAGTTGACGAACGCCAGAAACTGATGCTTCTATTCCTGCTGGAGCTTTCCATATTCCTCTTTGAGCGTCTGTACGGGCGAATATACCGGCGATAATTCCGCAAGGCACAAATTCCTGAATGCGATTTTCTTTTAACGGATCGGGCATCTTTAACCTGGGAAAATACGCAGCCGCATTGGTAGCAAAAGCATTACCTAAAGCCGAACGTAAGTCATTTACACCATCTTTTGCAGCACCAATTGTTTTCCAATTTGCTGGAGGATCTACAATCAGCATTGCTCGACGCTTTTTGCAGTATTGAGCTGCGGGAAACAAAGTAGTTACTGCATCAACTGAGTCTCCGGGGTCTCTAGTTATTGGTGGTATGCATAAAATATTAAATATATCCGCCGCATCTAAAGCATAAATACCTGTAGAAGGGCCGCTATTTGGGTCGTCTGGATCGCTTTCTTCTCCCGTATAGTCACCATAGGTAGGCAAACTACCATTAGCACCTCCAGAAAAACTAGCATCTCCTACTGATGGACGTTCGCTAGGGTTATTCGCAACGCTGACTAGTGCAGACTCTTGTTCTAAAACTGTAGTCACAAACCTAGGGGAATCTTCATCTGCGGAAATGTTACGAAACTCTTCCAATACTGCGGGTTGATTTAAAGGCTGACCATCAGCATCTTGGACTTGTTGAATTTTGAGATTGAACAGAGGGGCTTCATTCGGTCTTTGGGGTCTGGTTTCGTAATTTACTACGGCTTTCAAACCGTTCATCCAATCCCCTTGGCTATTAGCTTCTAATTCCAGCCCCCCTACAGTTGCAGTTGCTTTGGTTGCATCACTAGCAACTACTCGGATAATAATTGCATCCGTACCACCATTGAGAAAATACTGCTGTACGGCGTAGCTCATGGTACTCTTAACCCATAAGCCACCAAACTGACGATCAAAGTCGGCGAAGCTTTGAATTCTTACTGGTTTATTTGTCTGTCCTCTGCTTGCAATTCCGATAAAAGCAGTTATGGAGGTTGCAACCCCAACAATAGTACGTACACCACTAGGGATTTCTTCTATATAAACACCTGGATAGGTGGGAGCGGTAGGCATAATTTATTCCTCTCTAATAACTTTATTACTTACAACTTATTTTCATGACTATTAATTTTGAGTGAGTTAGGGAGTCGCATCACGTCCGACTAAAATTTCAATATCAGCTTTATTTGGATCGGGTTTACCTTCTTCTGTGGCTTTTTCATGTTTATTAGAAAATTGAATTTGGTTGAGATTTTCCCCTAGTAATGACACAGCCCCCGTACCCAAGAAAATTTGGGGTTGATCGAGTTGAATTTCTTTATCGCCAACTTTGTAAGTTAGTTTTTCTTCAGAACTATACAAATTTGATGTAATCAGCAAAAAGCTAATCTCTCCTTTATCTCCTTGTGCAACGTTAACAACTTTGTCTGTGTCACCTGGTTGAATAGCGACTTCGATTTTGTTATAAGCCTCAACCTTTATATCTTCATTAAGGGAGGCTTGGGGTCCTCCCGAAACTTTTGCGCTAAGTTGAACTTTGATATCTACCATTGAAAGTTTCCTCACAAAGTATCAAATACTAAGAAAAAAATGTCTGTCACACAAAAAATAATATTTTTGTCAATAGCTGTTAAAGAACCACTATATTTATGCATGTAAATATAAAAGCAAATGTATTCCGAAATTACACGTTTTTTTCAGAAAAATCACTATTTTTTAATATTTATAATTCTCAGGTTTGTGACTTAAGCTGAATGCATAAATATTGTCAACATAGAGTTTGACATAGTTGTAATTCAAGTTTTTATTGTTAATAATTGAAAATGTAAGTTTTAAGGAAAACTCGCTGTATGTTAGGAAATCTTTTTGCTTGGTTAATACTAATTCCCTTTATTCTTGCGTTTGTTGTTGGGTTTCTAGCTTACGATTTTCAAAAGCCGACTGTACCACCAGATGGAGAATTAAACAAACCGTAACAAGTTAGGAATTATGAGTTAGGAGTTAGTAATAATTTACTTACTCTTAACTTTTGACTCAGAATTTTCTTGTTTGTTTGTATTGGTTTCTGTTTGAGAGTCTCCCTGCAAAAATTTAAACTCGGATTCAGGTAATTCCAATCCCAATCTCTTTTTAGCAAAATTCTTCACCCAGTTAAAAACTTGTGCAAAAGAATTTACAAGCGATTTGATAGTATTCTCTACTAATTTTTCTGGTTCTTTATTTGGCGATTCCATCCATTGGCGAAACTTCCAGCCAATGGTAAACCCGATGTGCCATACCCAAAGAACGAACACCACCACTAATAACAACAGCATCAAAAGCAATATTGCTGTTTCTTTTAATAAGTTCCAGGTTTTAACTAGAGCCTGTTGATAAATTTTAGCGGTGTTTGGGCTAGAGAGGTTATCCCAAAGAACATTAGCTTGATATTGGATGAGCTTCATGGTTTTTATTCTTAATCACCCATACTCATGAATTTACTTGCAAATGATAACTTCGGTATACCGAAATCTGTTTTTAGCAACAATTTGTATCATTTTTTGTATTGCAGATTGCAAATTATTCACCATAGTCGTGACTATTCAGGTAAATACGGTGAATAAAAATTTGTGTTATTACTGCTAGAAATATATCAGATAAACAAAGGCAGCTACTTCTCGCTACTAGTCTATATTTCATTTATTCGATATTTAATTTATTTTTAACCTATCCACCCAACTAAGTATGATACAAGGCTTTCAGTATAAATATTACGCTACGTTATATTTCAATTAGGTTGGTTACAAATTGCAAAGTGTAATAAATAATTATTAAAACCTCTCTGAAATTTACGGCAGTAGAAAGTTGATTATGGTATCAGAAAGAAAGAAAATATCAATTTATACAATTAATTCGTAGTTGTTAATATCTATTTTTGAGTTTTGACTTTAAACTACAAACTATATCGAGGTTAACCGCTGTCGGTAATTTGAGGGGTTTAGACAATGACTACTCGTTCGCATTCTCAAGTCCAAAGAAACTCAGAAACCTCTCAAAAGTTGGTTTCTGATGGACTGCTGCAACGTTCTGGGCAGCAGACGGAGAGAGTCAACGAGCAAGAAGATTTACAAAGCTTTAGAGAATCTCAAACTTCCCAGGAGTCTGGTGTTAGCTGGGATTTTAGCTCTGTACCAGTACGTCATACTTCTTTACCAAAAATTCAGCCTAAGTTGAATATCGGGCAACCGGGAGATAAATACGAGCGAGAAGCTGATAGGGTAGCAGAGCAGGTAATGCAGATGCCGCATCCGCTTCCCGAAAGAAGGATAAACCCCTCTCCCCTTGTGCCTGCTCGTTTTCTATCATTAAATTCCGATTCTGAAGAACAGTTGCAACGGCAGGAAATAGAAAAAGACAAGGAAGACGACGAAGAAAAAATTTTACAAGCAAAACCAAATAAATCAAAGACACCCAGAGTTGCACCAAATTTAGAAAATCATCTTAATGCCAGTAGGGGAAGCGGACAACCTTTGCCTGAGTCTACCCGTGTTTTCATGGAAGATAGATTTGGGACTGATTTTAGTGGCGTGCGGGTGCATACTGATTCAAATGCCGTACAGATGAATCGGGAGTTAACAGCGCAAGCTTTTACTCGTGGCAATCATATTTATTTTGGTGCGGGTAAGTCTCCTGGTAATAATGAGTTGATGGCGCATGAGTTGACGCATACTATTCAGCAGACTGGTGGACAGATACAGCCTAAATTAATTGATAAAGCTACAAAAACAATAAATAAAATCAATCATAAGCCCGATTTAAACCTTCAGATGAAGGAAGTACCGGGATATGAGATAAATACACAGATAAAGCAAGAATTAGCAGCAAACAATACTGTTAATCGAGTCGCACCCCTAGAAACTGCCCCGAAGCAAGAAATAAATACAACATCTGTTACTTCCGAAGAGAAACAAGAAGAAAATCAAGAAGCAGCACCTCTAGAAGCTGAGAATCAAGAAATTACTGCAACAGCTACTGAAACAGCAGAGGAAGAAACTGCTCCTACTTCCCCAGAATCAGATCCAGATTTTCAAGCGGTAGTTGCTAAGGCTAAAAGTGTTGCAAGTAAAGAGAAAAAACACGCCCCAGCGAGTACGAAAGCCAAACAAGCCCAAGATGCAGCCGAAAGCCCTGCAAGTGAAATAGAAAGCAAAGCCCAAGCGAATCAAGTGGGTGAAATGGAACAAGCTCCCACCCCTGGTTTTAATGCTGCTGCTTTCAAAACTAAATTAATGGAGCGCATCAAGGAAGCGGCTCCTAAAAATCTTGAAGAAGCGGATAATTTTAAAAATAATCATAAATTGGCTGGTGTTAAAAGCCAGATGCAAAATACAGTCGAGCAAGAGCAAACTGCATCTCAAACACCATTAACAGAGAAAGCGCAACAAACGCCAGATACCAGCATTATCAAACCAAAATCAGTAACTCCCCTAGCTTCTAACGAAGCGGGAGCAGCAACAAAAAATATTGGCGCTCAAAAAGCTGTTCCCAAAGCCAAAAAACAAAGTCAAGTTGAAGCACCGCTACAAGAAAATAGCCAAAAACTTGAGCAACAAATGGCTGAAGCTAATGTTACTGAAGAACAATTAGCTAAATCTAATCAACCACAATTTAAAACCGCTTTAGAAGCCAAAACACAAGCTCAAACCAATGCCCAACTTGCACCCCAAGAATATCGCCAATTTGAGCAAAACCAGCTAACCCAAGCCCAAGGAGAAGCCACAGCCACAGCAGGAGAAAAACTGCAAGGAATGCATAGCGATCGCACTCAATTATTATCTGGGGTACTACAGCAGCAAGTTGAAGCTAAAGGTAAAGATGAGCAAGCACGAGCTAAGGTTGCTGGAGATATTCAAGGAATTTATCAGCAAACTAAAACCAAAGTTGAGCAAATTCTCAACGGTTTAGATAATAAAGTAGATACAGAATTTGAAACTGGTGCCAATCAAGCCAAAAAAGCCTTCGAGGATTACGTAGATGAAAAAATGAAGGCTTACAAAGATGAGCGCTATAGTGGTGAATTAGGTTGGATTCGCTGGGGTAAGGATAAACTACTGGGTATGCCTTCAGAAGTTAATGTTTTTTACCAAGAAGGACGACAATTTTACCTACAAAAAATGGATGTTGCCATTGATAAAATTGTCAACATTATTGGTAGCGGCTTAATCGATGCTAAGTCAGAAATCACCAAAGGTAGGCAGCAAATTAAAGAATATGTAGCTCAATTACCCGAAAATCTGAAAAAAGTAGGGCAACAAGCTGCTACAGATATTCAAAGTCAATTCAACGAGTTAGAACAAAGCGTTGAGGGCAAACAAGATGAGTTAATTAATAACCTCGCGCAAAAATATAACGAAAACCTGCAAGTAATTGATTCGGGCATCAAAGAACTCAAAGCTGCTAACCAAGGTTTAGTCGATCAAGCAACCAATGCCATAACCGGAGTCATCAGCACTATCAAGAACCTCAAAGAGATGCTGCTGAATGTCTTGAAAAAAGGCGCTAGTGTAATTACTAACATAATTGCAGACCCCATCGGTTTTTTAGGTAACTTAATTAGTGGTATTAAACAAGGCTTTGAAAACTTTGTCGCTAACATTGGCAAACACCTACAAGCCGGTTTGATTGGCTGGCTGACGGGAGCCTTAGGACCAATAGGTATTCAAATACCCGACGATGTCTTTAGCTTACCGGGAATATTTAGTTTAGTAACACAAGTATTAGATTTAACGTTTAATAACATCCGTAGAAAAGCAGTCAAAATGTTTGGCGAGCCAGTAGTAGCTGGTATGGAAAAGAGCGTCGAAATTTTTCAAATATTGCGATCGCAAGGTGCAATGGGGCTATGGGAACAGGTTAAGGAAGACTTCAGCGATTTAAAAGAAACAGTTATCAGCGAAATCAAGAACATGGTAATTACTCAGGTGATAACCGCCGGGGTGAAGTGGATTCTGAGTTTCTTAAATCCAGCATCAGCATTTATCAAAGCCGCAATGGCAATTTATGACATTATCAGGTTCTTCGTCAATCGTGGTAAACAAGTATTGGAATTGGTAAATGCGGTTGTCGATGCAGTAGTGAAAATTGCTTCTGGTGCTGTTAGTGGTGCAGCTAAGTTGGTTGAAAATGCTTTGGCGAAAGCTGTACCTGTGGTGATTGGTTTCTTGGCTTCTTTGTTGGGAATTAGTGGTTTGGCGAAGAAGGTTGAGAAGATTGTTGGTAAGATTCGGGAGAGGATTGATAAGGCGATTGATAAGGTGCTTTTGAAAGCTGAGGGGTTGTTTAAAGGGGAGAAAGGTAAGAAGAATAAGAAAGCTAATAAAGAAAAGAGTAATCAGGAAAAAGATGAGCGTTCTCCAGAGGAAAAAGAGCATGATTTAAAGGCTGCTCAGAAAGCCTTAAAAGAAATTATTTCAAAATCTATGAGTATCGCTCAAGTAGAAAAGGCTTTTCCAGCTATAAAAAATAAATTTAGATTGAAGAAGCTTGAGTGGGAAAAATTAGGTACTCCATCCGCTGCTATTATGATGGAAATCAATCCAAAGGCAACTATTGATCTTAACCAACAAGGACCCTTAAAACTGAATGAAGGAGATACAACCCACAGCAATAGACTAGGACTTAGTCAAGATATTACTTTTGAAGGCGGTACTATTGCAGGTTTTCCAGTTGGACGAAAGATGACTGCTACTAAATTAGGTCCTAATCATCCACAAGGAGGAGGTCCTCAAAGCAGTGCACTAGCAAAAATTATGGAAAAATTACCAACAGATCCTAAAAAGGGTAATGATGAAAAATACGTCAAAGGTCATCTCTTAAATGATAATCTTGGTGGACCAGGAGAAAACAGAAACTTATACCCCATTACTGCTGGTGCAAATAAAAAACATGTAGACCACGTCGAATCTTACGTTAAAAAGTGGGTCAATACGGAGGGGTACTGGGTTTATTACAAAGTTGAAGTTGACCAAAAACAGATCAATCTTTCTCAAGGTAAAGTTACGGCTGATTTAATTTGTGAAGCTAATAAGCTGGATGCAAATGGTAAGAGGACATCTGAGGATGCACTGAAAAAAACTATTCACTCTGAATTAAATAGCCAAAGCGGGGTTGACGAATATAAAGCTGAGTTTGATAGTACAGCCCACCAGAGTAGAACAGATCCAGGATTTGATAAGGACAAAGTAGAATTGTCAAAAACCAAGGAAGATTCAAGTTTTCCTCAAGGATTAAAGAATAATATAAAAATAGTAATTTTAGAAAATAATAAAATAATAAAAAAAATGCTTGTTGATAAAGAAACAATCAATGAGGCAATCAAAAATATTGAGCGTAAGACATTCAGACGGAAGATATTAAACGATCTTGATTTTAACTATGAAAAGTATAGTGAAAACCAAAGTAGGCTTAGTGCATGGAACAGAGCTATTAATGATTTAAATCAAGACTCAAATAAAATAGTGGAGTTTTTCAACGCCTATAATTATCAGCTAAACAATTATATAGCTGAAATAGAGAAGTTTGGAGATAATTTTTACTGGCAGGATAATAAGAATAAGACAAAAAAAGATATTCTAGAAATTGCTAAAAACCCTAAAAATACAGAAATAGGAATTAAACTTGCTCAACAGAGATTAAAACAAACAAAAAAGGTCCGCTATATGTAAATTTTTTATGATAGATCGTAGCCCGTATCTTGGGATTAGGAACATAACCCAACCCTAATAAAACGACTTGAGAAACCAACCCTCAACATCACCATATATTAACTATCATTACAAATTTAGATAAAACCTAAAAAAAACTTCAATTTTAACAGCTAAACGCTATTATTATACATACGGCTAATAACTTAATAGTTAAAAAATTAACTCCACCGATATTAAAAATTAAAAAATATATCGGATTTGGCCCAATTTTATACTCCAAATAAGTTGGTTGAGTAGCAAAAAAATTCCGCATAATTACTTATTCATACAAGCATAAAGGATATCAGTTGATATGACTGCCTATCCCCCATATCCACGACTGCTAAAAGGTTCTATTGTCGTTCTAAATTCATCTGGAACCATAGTCTCAGACATAATTCCCTTTCAATACAACCCAGAATCTCTGAGTCGTACCTTGCAGGTACAGGCAACGAGCAATGAAGGTGGCGAACGTATGGAAGCCTTACGATTGGAAGGGGCACCAGTAGAAACTTTCAAGCTGGATATAGAAATTGATGCCACCGATGGGTTGGAAAAAGGTCAGGTGTCCGCCGTTACTTTGGGTATATATCCACAATTATCGGCACTGGAAACCTTGATTTATCCAACTAGCGGGCAGGTTAAGAAAAATATGCGGCTAGCTGATAAGGGAAGCTTAGAAATTGTACCGATGGAAGCACCAATGACTCTCCTGGTATGGGGAGTTCAGCGTTTGCTGCCCGTGCGGATAACAGATTTCAGTATTACCGAAGAAGCTTACGATATCAACCTTAATCCCATACGTGCCAAAGTTTCACTTGGTTTGCGAGTCCTCAGCTATAACGATTTACCTTGGAAGAAACGTGGATCTCAGCTGTTTATGGCGCATCATAAATTCAAAGAAGGCATGGCAAGGCTAAATAGCATTACAAATCTTACAAGTTAAGGCTTAATGTAAATGCTCGATTTAGGTAGTTAGGAGTTAGGAGTTAGGAGTTAGGAGTTAGGAGTAATGAGTAATGAGTTTTAAATCCTCAATGCCCCATGCCCAATCCCCCATGCCCAATCCCCAATCCCCAATGCCCCATTTTTATGTTTGAACCAACAAGCCGCTATTACAACTTAGAAACTGCTCAAATTACTACTACTGATGGTCGTAGAATTGCTTATAAGCGCCGTCGCTTTTTACCCCAGGGTAGAGATATGCCAATTGCGGAAGAGGTGATTGTTAAAGATGAGGACAGATTGGATTTGATTACTTTTGCAACTTTGGGAGACTCAGAACAGTTTTGGCAGATTTGCGATGCTAATAATGCAATGAATCCTCCTGAGCTAATTGCAGAACCCGGTAGAATGTTGCGGGTTCCGATTCCTGAAGTTTAACGACGAACGTTAAATAATTAATGTTGATGGGCACATTATTGTTTGTAGTTGCGCTTCAGCGCCTTCGGATAAAGGAATATGACGGGTTCGTTTCTCTTCAAATCTAGGGAGACGTAACAGTGAATGGGACAAACCACTAGTAACTCGCGGATTATTAGGAAAATATTATGGCAAAAGGGATTAATCTGACGCTGAAAATTGGTTCTAATAATCCTCAGCCTGCTTCCAGGGAGTTGATGGAGGCTCTTGATAGTGTAGAAGTTACTCACAATGATACGGGACGTTCTGGGTTTCAGATTGTTTTTGCGGTGGGGCGCTCTGGTGCTAAAGACCAAAAAGATTACAAATTACTACGGAATTCTTTACTAAAACCTTTTAATCGGGTAATTCTAATTGTGTCTTTTAATGCCAAACCCAAGATTCTCTTGGATGGGATTATTACCAATCAGCAGTTAGCAGCTAGCAACGAACCTCGGGGTTCTACCCTAACTGTTACTGGTGAAGATGTCAGCGTAATGATGGATTTGGAGGAAAAATCGGCGGAACATCCCCAACAAGATGAGGCAACTATTTCTAGAATGCTGATTTCTAAGTATTCTAAATACGGTATGGTTGCTAAAGTCGTTAAACCGTCTTTAAAAGAACGTCCCACAAAGAATGAAAGAGTACCCGTACAGCAAGGTACAGACTTGGAATATATCAAGCAGCTAGCAGAACGGTTTGCTTATGTTTTCTATGTCGAACCTGGTCCAGTTTCTACTAAAAATACCGCTTATTGGGGACCGCCGCGACAAGGGACTAAAGTTCAAAGGGCGCTAACTGTAAATATGGGTTCTTTTACCAATGTTGATTCTCTTAACTTTCAAAACAACGCTCTGGCAGCAACTACGGTAGCCGGTAAAGTTCAAGATCGGAAAAATAACCGCATTCAAAAAGTGCAGGATAAAAGTAGCGATCGCCCTTCTTTAGCTCAAAAATCGGCTGTAAAATCTCAAACTAAAGTGAGGGTGAAACAGTTCCGGGAGACTGGACGCAGTACGGCTCAGGCTATTTCTCGCGCCCAAGCTATGATTGACCGCTCTGTAGATGATGTAGTTACTGTGACTGGGGAATTAGACAGCGTTCGCTACGGGGGACTTTTGGAAATCAGGGGAAAGGTAGGGTTACGGGGTGCGGGCTACAGCTACGACGGTTTGTATTATGTCAAAAGCGTCACTCATAAAATCCGCAAAGGCGAATACAAGCAAAGTTTTACAATTACTCGCGAAGGAACGGGAACAACAGTGCGAGGAGTGAAAGTATGAAGGAATTTTGGGGGAAGTATCGCGGTAAAGTTACCGGTAGCAAAGACCCCTTACATTTAGGCAGGGTGCAGATAGAGGTTCCGGCAGTGTTGGGAGAAGGGCGCAAAAGTTGGGCTATGCCCTGTACGCCTTATGCAGGTAAGGATATTGGTTGGTTTACTGTTCCACCTGTAGGAACAAATATTTGGGTTGAATTTGAAGGAGGAGACCCCGATTATCCGATTTGGTCTGGTTGTTTCTGGAATGAAAACGAACTGCCAAAAAATGCCCAGGTGGATGAACCAGATAAAGTACAGGTATTTAAGACTGATGGCGTTACTGTTACGATTAGTAATTTAGGCAGTAATAAAGGCTTAACCATTGAAGTTGATAAACCCGTAGTCAAGCGCAAGCTGAAAATGGTTTTTAATGCCGATGGGATTGAAATTAATAATAAAGATGAGACAGTAGTTAAATTAACCGCAGATATTATTGAATCAAATAATCAGGAAAATTCTACTATTACTGTTACTAAAGATAATATTCAACTTAAAGAAAATTCTGTCGAAATCAAGCTGACATCTAATAGCATCGATTTAATTGATAATCCCTCAACTATAAAATTAACTACATCGGGAATTGAATTAGCCAATAATCCAGCCAAAGTAAAAATCGCACCGGCAGCGATTGAACTCAGCGACACTCCCGCAACCACAAAAGTTGCTCCTTCCGGAATCGAAATGAGCATGGGTGCAGCTAGCGTTAAACTTTCCCCCGTCAGCGTCAATGTTAACAACGGAGCCTTGGAGGTGATTTAATGCCCGGTTTTTTATTAAATGTCGGTTCCGTCGTTTTTTGCGCCCACGGCGGACAAGCAAAACCAACCGTACCCAACCCTCGGGTTAAAGTCATGGGACAACCAGTAACCACCTTCGGACCTCCTTATATGGTTGCTGGTTGTGCCAATCCACCACCACCGGTAAATGTGGGACCTTGTATAGTTTGTAATTGGATTACTGCTTCTTTACGAGTAAAGGTAATGGGAATGCCCGTATTGTTGCAGGATAGTAAGTCTGTTTGCGTGCCTACTGGAACCCCAGCTAATGTGGTATTTACGCAGCTACGAGTTAAGGCGATGTGAAAGGAATTGGGAATGGGTAATTGGTAATTGGTAATTGGTAATTGGTAATGGGTAATGGGTAATTGGTAATTGGTACTCCTAATAACTAACCACTAACCACTAACCACTAACAACTAATAACTAACAACTAACCACTAACTTCTAAAATGCAGCAGATTAATTATCCATTTTTGATTGATAATCGCGGTAGGATAGCGTCTCCGGATTATAACCAGCATATTCGGCAGATGATTGAGCAGGTGTTGTTTACTTTTCCTGGTGAGAGAGTGAATCGTCCAGATTTTGGCACTGGTTTACAACAGTTGATTTTCGATCCTAATGGTGGTGAATTAGCTGCTGCAACTCAGTTTTTGGTGCAGGGTGCTTTGGAGCAATGGTTGGGAGATTTAATTGAGTTAGAAGCGGTAGAGGTGGAAAATCAAGATTCTAAGTTAACGGTGACTATTCAGTATATTGTGAAGCGTACTCAAGAACAGCGATTGGAAGAATTTTCTCGTGAAATTTGATAAGTACTAGAAAAACCTCTGCGCCCCTCTGCGCTTAACTTTGCACTCCTCTGCGTTCATCAAAATTTCAGTTGGGTGCAATACAGACTCAACCTCACCCCCTTCCCCTCTCCTTATTAAGAAGAGGGGGGAGGTTCAACCGAAATTCGCTATAACCAACCACTAACAACTAACAACCAACTCTTATGAGTACCCAATACTTATGCAAAAACCAACTAAGACGGGCTAAAGTCCTCAGTAAAAATATATTAAACGGAATTGATTATTTAGAGGTTGGAGCAGATAGGAAAACACTGCTTGTATATTTTTTACATAATCTTCCGGGTGTTGCTCAAGAAGATTCGGTACCTGCAAATTCCAATGCTTTAACGGCAGACAATATTTTAATTACTGGTGGCATAAGGGTTCGTAGTATTGTTGTTGAGTCTGTAACTTCGTTTGAGAATCTTTTGACTGTAAGGGTGAGTGGTAATAGTGATTTTTCTACTTATACTCTAAAGTTAGTTGATTCTGATGGTATAACTGCTCCTAAAGGTTTTGATTCTCAACTTTCTCAGGTAGATTTTTCTTTCTGGGTTGAGGATAGAAGCGAGTTTGACTGTAAAACTCCGGATGCGCCAACGGAGAAACAACCACCTCCACCTTTTATTGATTATCTTGCTAAGGATTACGCTAGCTTTCGCCGTTTGATGCTGGATAGGCTGGCAGTTACCGTACCGGATTGGCAAGAGCGCAATCCCTCGGATATTGGTATTTTGCTTGTAGAAATTTTAGCTTACGGGGCAGATCATCTCAGCTATTATCAAGATGCTGTGGCGACGGAGGCTTATTTAGGTACGGCTCGCAAACGGGTTTCGGTGCGTCGTCATGCGCGAATGTTGGACTATTTTATGCATGATGGTTGTAATGCTCGTGCTTGGGTTGTACTAGAGGTAGAATCTAAATCTCAGGCTGATGGGTGTATTTTGCAGGCAGCCGTTAACAGCCTGAAACTACAAGAAAATAAAATCAAGACTCGTTTTTTAACAAAAATCAATTTAGCTAAAATTCAAGGGGAAAAAGATGATATTGGCGTGCGGATTAAGCCGGAAAAATACGAAGAATTATTAAATCAACAGCCGCAAGTCTTTGAACCGCTTCACGATATTACTTTATATGCTGAACTTAACAAGATTAATTTTTATACCTGGGATAACGAACAATGTCGATTACCCAAGGGAGCAACTAAAGCAACTTTAGATTTTTGCGATAAGCCACAACTTTGCAAACAGCTTGAAGGTAGGGTGCTAATTTTTGAAGAAGTTAAAAATCCTCAAAATGGAGATTGCTTTGATTTCGATCTGACTCATCGTCATGCGGTACGGTTAACCAAGGTGACAGAAACTACAGACGCTCTTAACGATGATAGAAAATTATTGCTGGTGGAATGGGCGGTTGAAGATGCCTTACCCTTTGATTTATGGATTTCTAATTTAGATAGTAAAGGGGCGCAAATTGAAAATATTAGTATAGTTCGCGGTAATGTGGTTTTAGTGGATCGCGGTCAAACTGTAGAAGGTGATGATGCAGATTTGGGTACTGTTCCCCAACAGGGTAAGTACCGTCCTTTATTGCAATTTGGTCCTTTGACTCAACAAGGATACGTCCGGGATAATCGCGATTTATGGGTAACTTTTAACCCTGAAGCTTCTGCAACATCGGCAATGAATTGGGAAATGCGCGATGTGAAACCGAGTATTTCTATATGGGAACTAGGAAAACGACAAATTCCCTGGTTTTCTCAGCAAGATTTACTTAATAGCGATAGATTTTCACGAGAATTTGTTGTAGAAACCGAAGACGATGGACGTACCTACCTGCGTTTCGGGGATAACCAGTTAGGAAAAAGACCGACACCGGGAACCAGCTTTCAGGCAATTTACAGAATTGGCAATGGTAAATTAGGTAACGTTGGTGCCGATACTATCAGCCATGTAGTTACCGATATTGATGGTATTACCAAGGTATACAATCCCTTACCAGCCCAAGGCGGTACCGAACCAGAGGCTATTGAAAAAGCCCGTTTGGATGCACCCCAAGCATTTCGTACCCAGCAACGCGCCGTCACTGCATCCGACTACGCTAACGTTGCACAACTTTACAAGGGTGTTAAGAAAGCAATAGCTAACCGCCGCTGGACGGGAAGTTGGTATACCATTTTTATAACTGTAGACCGAGAACAAGGGCTACCAGTAAATGAGGATGAAACTTTCAAGGATAATTTGCGTAATTTCTTGGAAAGCTTTCGTCTCGCCGCACACGATTTAGAAATTGAAGGTCCCCGCTATATTCCTTTAGATATAGCGATGACGGTGCATTTATTACCCGATTATTTCCGTAGCAGCGTCAAAACAGCGCTTTTAGAAACTTTCAGTACTTCGGTATTATCCAACGGTAAATTAGGCTTCTTCCATCCTGATAATTTTACCTTTGGGCAACCAGTATATCTGAGTCAGGTTGTAACTACAGCCATGCAAATACCCGGAGTCAGTTCCGTTGAGTTAACAAAATTTCAACGCTGGCAACAACCATCCAATCGGGAATTAGAAAACGGTCAAATTCCCTTTGATAGATTGGAAATAGCCCGTGTTGACAACAATCCTAACGCCCCCGAAAACGGACAAATTGTATTCAATATGAAAGGAGGAAGGTGAGCAGTGAACAGTGAGCAGTGAGCAGTTAATACCATAAGTGGGAATTAGGTATTGGGGATAGAAAGTTAGGAGTTAAAAGTTATAGAATTTTGGATTTTAAATTGAGAGTGAGTAGTGAGTAGCAAGTAAATAATTACCAATTACCAATTACCCATTACCAATTACCATGACTAATTCAGATTCACCAAAACCAATTTACAACAGACCTGGATTGCCAGCTATAGTTTACCGCGTTGGTGACTATAATTCTTTTCGGCAGCGTTTGATATCGCAACTATCTAGCCAAATAGTACAAAGCGATACTCCATCGACACGCAGACCTCTGACAAGACTGACAACTCGTTCCAATGAAGATCCGGCGATCGCGCTTCTTGATGCTTGGGCTGTAGTTGCCGATGTGCTGACGTTTTACCAAGAGCGGATTGCTAATGAAGGTTATATACGCACTGCGACAGAACGATTTTCGGTGTTGCAGTTGGCGCGTACTATTGGCTACGAGCTAAGTCCGGGTGTAGCTGCTAGTACTTATCTGGCATTTACTGTGGATGATGCTATTGAAAGCGTTACTCAAGCCATTGTTCCCCAGGGAACTCCGGTGATGAGTATTCCAACGACAGATGATGAAGTACCCCAAACTTTTGAAACTAGTGCCGAAATTCTGACGCATCTCGACTGGAATAGTATCCAGCCTAGGTTAAGTAAACCGCAGGTAATTGCTGAAAATATTAATCAAATTTATTTAGAAGGAACTAGTACCCAACTGCAACCGGGAGATTGGGTTTTATTAGTTGGCAATCAAGAACAAGATATTGAAACTTATTTACTTAATCTGACTGCTGTAGAATTATCGGCAGATAATAATTACACGTTAATTAGTTGGGAGAAACAATTACCGCAGGCTATTAAAAGTAGACTTCGCAATCCTGAAATTTTCGCTTTCCGCAATTCGGCATCGTTATTTGGTAAAAATGCTCCCAATTGGGAAGATATGCCTGATGAAATTAAAAAGGCTGCTGGTGGTACGTTAGCTGGGGGTGTTTTTTGTAGCGAGGATAATGGCAGTAATTGGATTTCTGTAAATGATAATTTAGCAAATACAGATATTCTTTGTCTCGCTGCATCTAGTAAAAACTTGTTTGCGGGTACTCCAGATAGGGGAATATTTCGCTGGCAGGATGGTAAAAATTGGGAAGCAGTTAATGCTGGTTTGACTAACTTAAATATTCAAGCGCTTTATATTCAACCTGGGAAAGGATATATATTTGTTGGTACTCCGGGAGGTGGTGTTTTCCGCTCTAAGGATAATGGTGATAATTGGGTTCCGATTCATACGGGAAACGTGCAGGTACAAGGTAAAGGGGATAATAATTGGCAGTCTGTAAATACAGCTATTCCTAATACCGTTGTGCGTTCGTTATTAACTTATTCAACCACAACAAATTCAGGTACGGGGACAATTGAAAGTGAAGGTAATAATGTCAGCGGTGAGGGTACAGAATTTACTAGAGAATTTAATGTTGATGATACCATCACAGTAGGGAATGAAAGTAGAAGAATAACTGAGATTAATTCCGATGTTTCTTTACAAGTAGATAGTCCTTTTATTAGTAATTTAGCTTCTGGTACCTCTTTTACTACTCCTAACCGAGAAATAAATTATATATTTGCTGGAACTGATAGTGGTGTTTATCGCTCTCAAGATGCAGGTAAAAATTGGATACCACAAGGTTTATTGGATGGATTATCTGATAGAGTAATTCGTGCTTTGACTAATGATGAAAGCGATATTTTTGCTGGCACTGATAATGGTATTTATCGTAGTAGTGATTATGGAAAAAACTGGCAGTCAAAAAGGTTGGAAGACGCAGATAATGTCTTTTCATTAATTAATTATCAACTAGGAGACAAAACTTATCTTTTTGCTGGCACGGATAATGGTGTTTATCGTTCTGAAGATGAAGGAGAAACTTGGACAACTTTTAACAATGACTTACCAGAAAATATCACAGTTTATGCTCTAGATAGCGATGATACAAATTTATTCGCCGCTACTAATGAAGGTATATTTACTTCTACAAATAACGGCGACTCTTGGCAAGAAATTAATCAAGGTTTAACTAAAACTAATATTACTTCTTTAGCTGTTAATCATAAAATATTTGCCGGTGCTTTATTTTCAGGGTTTAAAGAAACAGAGTGGTTGGATTTTGAAGTTACGCAACCGGAAATTGATTTAAATACCATTTATCCCAAAATTTTAGAAAATAGCTGGATTGTTTTATTAAATGAAAATCTGTTTCAAGCTGTTCGAGTAAACAAGGTATCTACTGATTCTGTTAGTAAATTCAATTTAACATCGGAAGTTACGCAAATTGCTTTTAATAATTCTGTTGATTTAAGCGGTTTTGGTAGACGGAATACTCAAGTATTAATTCAAAGCGAATCTTTAGCTTTAGCGCCGGAAGTTTTAACGGTGAGGATGCAGCAGGAGAATATTTTTCTTGACCCCATAAATAAAGATAAAATTTATCTGAGTAAATTTATTCCGGATTTGCAGTCAGATAAAACTTTGATTGTCAGCGGTAAGCATATCCGAGCTATCGCTGAAGATATTGGCGGCTTTTTTGTCTGGAATGCTGATGAAAATAAATGGCAGCGCCATAATCAAGGTTTAACTAGTACCAATATTCAAGCTTTAGCTGTTGATGAAACAGAAAATGAATATCAATATTATATCGGCACCAGTCAAGGTGTTTTTCGTTATTTAGATAAAAATCAAACTAATAATCCAATTTGGGAACCTTTAAAAAATCAAGGTTTATCAGATACTGATATACAAGCACTTTGTATTCCCCAGACTAAAGAACTTTTTGCGGGTACTCCCAGCGGAATTTTTTACTATTCCGATAGCGGATGGGAAGCAAGGAATCAAGGATTGGTACATAAAAATGTGCAAACCTTGGTAAGTTATCAGGAAGGTGAAACTATTTCGATTTTCGCTGGAACTTTTGACGGTGGGGTTTTTGTTTCTCGGAATAACGGTGAGAGTTGGAATTCTACTGGTTTAACTAATGCCGATGTGCAAACTTTGGTTGTTAACACAGAAACTGGTGAATTATTTGCTGGCACTTTTCAAAAAGGTATTTTCCATTCTGATAATCAAGGTAATAGTTGGCAGCAGTTAACAAATATTGAAAGAGGTACGGGTACGATTTCCAGCGATAATATTACGGTTAAAGGTGCAGGGTTGAATTCCCAACAGTTGCAGGTAGGGGATATTATTAATGCTGGGGGACAAACTCGGACTATTGTATCTATTAATAATGAAACCCAAATTATTACAGTTGATACCGCTTTTCGTCCCGATTTAGCCGAAAGAACTGCTTTTACGATTAATACGGGTTTAACTAATCTCAATATCACTTCGCTGTTGATTCTACCTCAAGAGCAAGAAACAATTTTGTTTGCTGGTACCGGTGGTAGCGGTGTTTTTCGTTCCCAAGATAACGGTAAAAGATGGCAGCAGGTTAATACAAATCTCCAAGATTTAGAAATTCGTACTTTAGTAAAGAATTCTAGCAATGAAATATTTTTAGGTACTGCTAGTAAGGGAATTTTTCATTCCGTTGATAATGGCGATTCTTGGCAAGCAATTAACGATAATTTAACCAATACCGATATCAAGGCGATCGCTATTTCTTCTAACGATAATAAAGACAATATAATTGCTGGCGGCAATGGAATTTTAATTTCACAAGATGGTTTTTATACTGTTCCTTTAAATAAGAGCGATTTGCTTTGGGTGATATCGCCGCCAGTAAAAGAAAAATATCTTAAATGGTTGGTGAGAGATATCAATGGTTTTGTAGGCAATATTGAAACCATCACCGATAAAGAACTTTTCTTACAGCCTGCCACGGAAGAAGATGGTATTGTCAGTGAAGTTTGTACTATCAAAAAACCACCCACAGAGCAGCAAAATCCCGTCATAGTCTTAAAAAAACCTTTAAAATACGCTTACGATCCAGAAACAGTGACGATTTACGCTAACGTAGTAATGGCTACCCACGGTGAAACCGTTGTTGAAGTTATGGGAAACGGTGACGGTACTATACCCAATCAAAGCTTTATCCTCAAACAGCCGCCGCTTACATATGTACCTGCACCTACAGCCAGCGGTGCTAAAAGTACTTTGGAGGTGAGAGTTAACGATGTACTTTGGGAAGAGGTTGATACTTTATATGAAAAAGATACTCATCTCCAAGGTTATATTATCCGTTTAACTGACGATAATACTCCGGTAATTACCTTTGGAGATGGTGAAAATGGCGCTCGTTTGCCTACTGGGGAAGAAAATGTTAGCGCTACATATCGCAGCGGTATCGGTTTAGAGGGGCAAGTTGCTCCCGAAAGTCTGACTCAACTAAAAGATAAACCTTTGGGTATTCTTGAGGTGATAAATCCTTTATCTGCTTCTGGTGCTGCACCTCCGGAAAGTCGAGATGAAGCCAGAGAGAAAGCACCATCCCAAGTGCGTACTTTGGATAGAATTGTTTCTATACAAGATTTTGAAGACTTTTCTCGCGCTTTTGCGGGTATCGGTAAAGCTCAAGCTGTTCCTTTATGGAATGGGCAAAGTCAATTAGTACATATTACTGTCGCTGCTGCGGATGGTTCCCAGGTAGATACAGATAGTAATCTTTATCAACAATTAGTTGCAGCAATTGATAATAATCGCGACCCCATTCAGTTTGTAGAGGTGGATTCCTACGAGCTGCAATTGTTTAACGTTGAAGCAAAATTGCAGTTTAATCCCCGCTATCAGCAAGAATTACTAATTGAAAATGTGACTGCATCTTTAAAGGCTAAATTTACCTTTAGCAATCGCAACTTTGGGCAAGATGTCACGGCTGCGGAGGTAATTGCTACCATTCAACAAATTGAGGGAATAGTAGCTGTGGATTTGGATGCTTTATATAAATTAGGTAGTAGTAAAGGCTTGCAGCAATCTTTGAAAGCTGATTTAGCTCGCTGGGATGAAGAAAATGATATTGCTAAACCAGCCCAGTTGTTATTGATAAATCCTCAAGATATTAAATTAACTACGATATGAACAAATATAGCGAATTTCAGTTGAGCAGAATAGACTATTACCTCACCCAGCCCTCCGGGCACCCCTCTCCTTATAAAGGAGAAGGGAAAAGTCAAGAGAATCGCTGTATTGTACCCAACAGAAAACTGCGATATAAATCAAGCTTAAATTCTCCTCTAAGACACACCTCTCCTTAACAAGGAGAGGGGAAGGGGTGAGGTTTTTCATGTTGACTACCTACCGATATTATGAACCAGCATTCATCAGTAGAAAGATTGTATAATTTACTTCCAGCTATTTACCGGATTCGAGACGAAGCTCAAGGGCAGCCGTTGAGAGCGTTGTTGGCGATCGCTGCTCGGGAAATGCAAGTTTTGGAGGATGACATAGACAATCTCTATGAAAACTGGTTTATTGAAACTTGCGATGAATGGGTAGTACCTTATATTGGCGACCTTTTAGACGCTCAGGAATTATACGCACAAAATAGTATTAATTATGGTCAGCAGCAGCGACGAGCTTATGTTGCTAACACCATTGCTTATAGAAGACGTAAGGGTACTGCTCCTGTATTAGAGCAGTTAACGCGAGATGTTACCGATTGGCGAGCAAGAGCGGTAGAATTTTTTCAGCGTTTGGCTACTACTCAGAATTTAAACCATCTACGCCCTAATAATACGACAGTTAATTTAAATCAGTCTGGGCAACCGGAATTTTTGGGTACTCCCTTCGAGCAACAGGTTTCCTACAGTATCAATATTGGTGATGCCTTAGAAGGTAGGGGATTTCACAATATACCCAATATTGGTTTATATATTTGGCGGTTGCAAAGCTATCCAATGGAGAAAGCTACGGCAAGGATGGTTGAAGGTGGTGAAGTTGATGGGCGTTATTATTTTAGTTGTCTTGGTTTAGAAGACTTTCCTTTATTTAACCAGCCGCAAACTGAAACGGATATTTTGCATCTAGCTGAAGAAATAAATGTTCCAGCAAAGTTGCGTATTCCACCTTTGAAGAAGGAGATAGAGAATTTATTAAATAAAAAAGAATCCAGCAATAATATTGGTTATTTTGATGCGACTCCGGTATTAGAAGTTTTTGTCGATGGGGAAGAATCATCAATTCCTCCGAAAGAAATTTTGATTGCTCCATTGAAGGTAGAGGATAATAATGATTGGATGTCGGTAAAATGGAATGATTTTGATTCTAATATAAGGGTAGCAATCGATCCAGAATCCGGAAGATTGGCTTTTCCTCCTTCGCAGTTACCTAGTGAAGTGGAGGTGAGTTATTTTTACGGTTTTAGTGGGGATATTGGTGGTGGCTCTTACCAAAGAAATTTATCGCAGGAAAGTTGTGTTTGGGAAAGGGAGATTTACCAAGAAAGTTTGGGTAGGGTAATTCAGAATTGGAATGCTTCTGTAGAAGTTTGGAAGTGTTTGCAGCAGGGTAATGGTGTTGCACTTGGGGAAATTTTTGTTGGTGATTCTGTTTCTTTGCAAGATTATGGATTAAATAACCGCAGGGAAGCAGAGGGAAGAGATGATGAGAAGTTGCAGGTTATTGTGTCTGATGATGGCGTGATAACTGTTAAAGCTGGGATGGTTAGGGATGAAAATGACAATCCTATTTGTTTGGAAAATGATTGTCAATTGGATGTGAGCGCTTTTGCTGGAGAATCTTTAATTTTATTTATTACTCATCAACCTGGTTTGGGTTTACCAGATTTACGTGTGGTTAATCATGGTGCCGGGGATGGGTGGTTATGTTTGGGTGTTGCTTTAAAGGAAGTTTTTGAGAAAACGGAGTCGGTAATTTCGATTCCGGATAATAAAACTTATTTTGGCGATTTAACTATTGTGATTCCGGCAGATAAAACTTTGAAATTTATGGCTGCCGATGGTTTTCGTCCCCATTTATTAGGTAATTTGTACGTACAGGGGATAACTCCTTTTGGTAATAATACTAAAAATATTAACAATCCCGGTGAGTTTATTTTAGAAGGTTTATTAATAGAAGGAAAGCTGACGGTATTACCGGGAAGCTTGAGAAGTTTGCATATAAATCACTGTACTTTAGTTCCAAAAGAAGGCGGGTTGAGGGTTGCAACTTGGGAAGTTGTAGAAGATGATGATAACAACGAAATCTCAGATGATAGTTGGACATTAATTGCGATCGCTATCTATTTTATTAATGCAATTCGCAGTTTAATCGGGAAGGGTACGCCAGGTAAAAGTTTTAATATATTGCTGAAAATAGCGATTAAGCAAGCACAATTGGTATTTTCCCAGTTTCGCGAGTTGATTCAATGGCGATGTGTGGATGAATATCCCGTTGCCGATGGTTGTTTGCAACCGGGTATGAAAGATAGTCTGAATTATCAATTGGATAATTCGCGATTAACTATCAGCATCTATCGGAGTATTTGCGGTGCCCTACATTTAGCTGAAACTGTTCCCACTTTGTTGATAGAAGAAAGCATTATTGATAATAATTTGGGTGCAGATACAACTGCCGATATAGAAAAATTAGTTGCCATTGATGCTTCAGGTACTGCTGTAGAGCAGTTGCAATCAAGTACTGTTTTTGGCACAACTAAAGTACGTAGCTTAGAAGCCAGCGATAGCATTTTTACTGGTAGAGTCACAACTTTACGCAAGCAAATCGGCTGTATGCGTTTCTGTTATCTTCCCGATGGCTCCCAAACTCCCCGCCGTTATTTATGTCAGCCGGATAAAGCTTTAGCTGAAGAGTTTGATATTAGTAAATTACCATCTGCTATTACTTGTTTAACAATAAATAAAATTGATTCTTCTCATCATCAATTAATTTCCGGTACTTCTGGTAAGGGTTTATTTTCTTATCAAATTAATCAAGATAATCAAAATCAATGGCAGCCGATAAATAAAGGTTTAGATAATTTCAATATCACGACTTTATTTTATCAGGAACAAGAAATCTATGCTGGCACAATTGGCGGTGATGTTTTCCGCAGTCAAGATAATGGTAATTCCTGGGAAAGTATTAATCACAAAGAAGAAATAGAACCCAAAAAAGCAACGGGTACAATTTCTAGCGCTGGAAGAATCGTAAAAGGAAATAAAACTAATTTTATCCAAGAATTGAAAATTGGCGATATTATTACCGCTAACGGACAAAAAAGAATTGTCACTCAAATTGATTCCAATTATTTCTTCTGTGTTAATACTCCCTTCGAGCCAAGTTTAGATAATGTTGGATTTAGCATAAGTAATTTAATTTTAAACACAGATATTACCGCTTTCGCAGTGCATGAATCAACTATCTTTGCTGCAACTGCTAGAGGTGGTGTTTTTGGGTTCTTAAAAGAACCAGATAAACCAGAAGAACCAGAAAAATGGACTGCCGTCAATGTTGGCATCACAAATCTTAATGTCACATCATTAATAGCGGGTGAAGATGGTTATATCTATGCAGGAACTTATGGAGGTATTTTTCGTACTCGCGATCCCGGTGAAGGGTGGTTGGCTATCAGTTTTGGTTTAGAAAACTTGGAAATTACAGCTTTAACAATAGATGTCACCAGACAGTTATTCGCCGGTACATCAGGGGGAGGAGTATTTCGTTTTGATGAATACAGTAATATTTGGACTGCGGTAAATGATGGTTTAAGCAATTCTTATATTACAGTTATGGCGGCAAGCGGTCAAAGGTGTGATGGTACTGTAAGCAGCGAGGGTAATAAATTAAATGGAGAAAACACCAATTTTACAGCGGATTTTCTTGGTAGAAGTATAACCGCAACCGGACAAACTCGCACCGTAACAAAAGTTGTATCTACCACAGAAATTATCGTTGACGAATCATTTTGTCCCGAATTACCAGCAGAAACAATTTATTCCTACGAGAAATTTTTAGTAGTAGGAACAGTTGGTGGGAGTATTTTTTATTCTGTTAATAGTGGAGAAACTTGGCAACAGGTTAACGCTGGTTTGAGCGATACGGATGTCAGCGATTTGGTTATTATTCCCTCAGTTGAGGAAGCAGGGAGCAGGGAGCAGGGAGCAGGGGGAGAAGAAAGAAATAATAGCGATCGCGCTATTTTTGTGGGGACAACTGCGGGTAATATCCTCTGCTTATCCGACGATATGCAAACATGGAAATCGCTTAATAGCGGCTTGGTAAATGTCGAAGATAAGCTGCGGGTTTTATCAAAAATACAGCCTAGATTTACTTCTAAACAATATGGCAACCCTGCCTACGCTCAACTAAGTCAAAATTGCGCTGTAGAAATTCGTACCGGTGCAGAAGACGGTTCCGAAATGGGAGTATTTAGTTATTTAAAGCAACCGCAACGTCAAGCAAATTTAGAAGCTAGTCTAAAAGAGTACTTGCGATTCGGTTTGAAAGTAGGCATTTTTTACGAGACATAAAGGAGTAAGTTATGAAAGGAGATTTCACCAGGTTTACATTTAAACCAGAGAAACATTACACCAGCGTGTTAATGCAGCAGGGGCGGGTGCAGTTAGATGCCGATTGGAACGAACAAGCAAATATCCACGCTTATTTTAACCAGTCTATAGCCCAAGATATGATTGGTAATTCCGGTGTTGCAAAAACTAGTGGTGGGTTTGAAATACAAATAATTGATAACAGCACGGATTTATTAATTACTCCCGGACATATTTATGTTGATGGTATTCTTTGTGAATTAGAAGGGAATTTATTTGATGTTACAGAAAGAGTTAATATTCAAAGTAACCAAAAACAAATTGAATTAAAAAGTATATATATAGATAATCGTATTTTAGAAAAAGGAGAGTGGCTGGAAGTTGAATTAATAGATAAAAATAATAATAATCAACTTAGTAAAAAACAGTTGCAAATTCAAGAAGTTGATAAAAAAAATCAACTACTAACTTTTAGAAATACAGAAAATATTGATGGTGATATAAAACAACTGCGTCGGTTAACTACTTATAATAATCAACCAGATTACCCCCAAGAAATACAAATCGATAGTAAAGACAATAGCAAAACTTTCGTAGAAGGAAAAAATTATCTTGCTTACCTAGATGTTTGGCAAAGAAACATTAGTGCAATAGAAGATAAAGACATTCGGGAAATAGCGCTACAGGGTTCAGATACAGCCACTCGTACAAAAACAGTTTGGCAGGTAAAATTATTAGAGTTGGAAAATAATCATATCTCCAAACATAATTTGCATACTTCAACTAAATGGGAAGCATTAAAAAAACGTAATGTCTACCTCAACGTTGATGATACAAATGCCTCCGGTGGTGAAGGAGGCTGGAAAAATCAACTGTACCGCGTAGAGATTCATAAAGGTAATCAAGAACAAGATAATTCAGCAGAAGTAACCTTTAAATGGTCTCGAAATAATGGTGCTATAGTATTCCCAATTAAAGAAATTAAATCAGATTATATAGAAGTAAGCAATTTTAGTCGCGATATTTCCGATTCCTTTAAATCCGAGCAATGGGTAGAAATTACCAATGATGTTCGAGAATTGCAAGGTGAACCGGGAACCCTGGTACAGTTAAGAAATATATCGCAAAACAAATTATTTTATAACCCAGCCACAATAGTTAATGACTCTAGTGATTCGTCAACTTTTCCCCAAGGGCACAATCTAAAAATTCGCAGTTGGGATAGTAATCATAGCAATAATCAAGACGCAATTCCTCTAAAATCTTCCGATCGGAAGGTTGTTTTAGAAAACGGCATTCAGCTAGAGTTTGAAGGCGATTCCTTTAAAACTGGCGACTACTGGTTAATTCCAACCCGCGCAGTTAAAGTTAATAAGCATCATATTCAGTGGACTTTTGATAGTTCAGATAAACCCATACCGCAACCACCGGAAGGAATCGAACATCACTATTCTGCTTTAGCTTTATTATCTTATCAAAACAACCAATTAAATCTCGTAGAAGACTTACGAGAAACCTTTCCATCCCTATCTAATTGCTTGGATAAAACAGGCGATATCATGACAGGTGCTTTGGAAATTCAAGATAATCTTTATATTACTGGTAAATCTAATCAAGATAATCAATATATTCCCGGTAAAGTTGGTATCGGAACAAAAGAACCCCAACAAAGACTAGTTATTCTTGATAAAGATGATATTAAAGGTAGAGTCGCAATTGGTTTTAACGATACAGAACAAACTGCCGCTTTAGCAATTAAAGAGAACGTTGGTATTGGTTATTTTAATATACCAAAAACTACTGCTTTAGCAATTAACGGTAAAGTTGGTATCGGTACAAAAGAACCCCAACAAGCATTAGTCATTCTTGATAAAGATGATATTAAAGGAAAAGTTGCTATCGGTTATAACAAAACAGGACAAAAAGCCGCTCTAGCAATTAAAGATAAAGTTGGTATCAATACAATTTTACCTAAGAGCGATTTAAGTGTATTGGGTAACGTTGCCATCGGCTCTACTAACTACACCGAAATTGCTAACGCACCAGATAACGGCTTAATTGTTGAAGGAAATGTCGGTATTGGTAGCCCAAATCCCACCTCTGCAAAATTAGAAGTAAACGGTGATGTCAAGATTACCGGGGATAGTATTAAAAATACCAATAACTTTAAAATTATTGATACTCAAAATCAAGATTGGTTAAATATAAATCCCGATGCAGAATATCCCGGTATTGCCTTATATAATCCCGTGGCGATTTCCAAAGGTGGCTTAGTGATTGGGGAATTAACTAAAATATCTGATGGTGAACTTAAAGTTAGTAAAAATACATTATTAGCAACAACATCTGGTAAAGTTACTATTGGCAATCTCCAACAAGTAAGCGAAAATACGCTGTTAGAAGTTGCCGGTAATACTATCATTGGCTCCTCATACATAGGCGATCGCGCAGCACCAGAAAATGGACTTTTAGTTGAAGGCAAAGTCAATATTGGCGATACGCCAAAAAATAATCAACCAGCCGAAAATGCTCAACTTTATACTCAAGGTGACGCTTATATAAGCAACAAACTTTATACAACTGATTTATCTGTCACGGGGAATATAGAACTTGGAGAATCAACCCAATTATCCATTGCTGAATTAGAAGTTAGTAAAAGTGCTTTCTTAGCAACTGCATCAGGTAAAGTTGGTATCGGAACTCAACAAATACATAATAATACCTTCCTCGGAATAGCAGGAAATACTACCATTGGTTCATCTTATATAAATAGTAAAGCTGCACCAGAAAATGGTCTTTTGGTTGAAGGGAAAGTTAATATTGGCGATACACCAAAAGATAATCAACCAGCGGAAGATGCTCAATTCTATAATGAAGGTGATGCTTATATAAACGGCACGCTTTATACAAAAGATTTAAGCGTTATAGACAATATCGAATTTGTAGAATCAACCCAATTATCTATCGCTGAATTAAAAGTTAGAAAAAATTCCTTTTTAGCAACTACTAGAAATAGTCAAGTTAGTATTGGTAGCCAGCGGAAGCCAAATACAAAAACTCTTATGGGAATTGCAGGAAGTACCACCATTGGTGAATCTTATATAAATAGTAAAGCTGCACCAGAAAATGGGCTTTTAGTTGAAGGAAAAGTTAGTATTGGCGGTACGATACCCCGAAATAATCAACAAGCCGAAGACGCTCAAATCTATACTGAAGGCGATGCTTATATAAACGGCACGCTTTATACAAAAGATTTAAGCATTACAGATAATGTAGAATTTGCAGAATCAACCCAATTATCCATTGCTGAATTAAACATTAGTAAAAATGCTTTCTTAGCAACTACTAAAAACAATCAAGTTAGTATCGGTACCCAGCAAAAGCCGAATGCAAAGACTCTTATGGGAATTGCGGGAAGTACTACCATTGGTGAATCTTATATCGATAGTAAAGCTGCACCAGAAAACGGTCTTTTAGTTGAAGGAAAGGTCAGTATTGGTGGTACTATACCTCGAAACAACGAAGCTAGAACATCACAACTTTACGTTAAGGGCAACGCTTATATTAATGATACTTTGTTAACAGATACCATTGTCTATAACCAAATGATGCAGCGCTCTTCACAGCAGTATAAAGATAATATTACCGAGCTTTCCATTCCAGAAAGTTTGCAAATATTAGAAGATTTAAAGCCTGTTAAATACAGTTATATAACAGATGAAACTAAAAGAATTCACGCTGGATTTATTGCCGAAAAATCTCCGGAAATTTTTACTTCTCCTGACAAAACAATGCTTAATTCCACGGGGATTATCGCAATATTAACCAATGTATTAAAAGAACATATTCATACAAATTCTGCTTTGAATCGCGTCATTGCCAATCAGCAGCAAGAAATTGCTAACTTACGAAAAAGAGTAAATAAATTAGAAGAAAAAAATAATAAATTATTTTGGTAAGTTAGACTCGTCCAAAATATAATCTAGACACTATTTGCAGGTTCATTTATTTTTTTCAATTGGTGTAGAAGAATGCTCTAACATCTCCTTCGCCATTTTTCGATGAATTATATTGACTAATTTCACACCTATTCTTTGACGACAGCGAACTAATATTGAGGCCTCAAAGGTGTTTCATTACTATAAGATAATATCCCTATCAAATATTTTAGATAAGGGTTGTTCTTGATTTACCAAATCAGTCTCTCTATCACTTATTCCTAATTTCTCTTTAATAATTAACGCCCTTAGTGCCATAGGAAAAGATTTAGCAGGTGCCCTTATATCCTCGGAAAAAGTTGAAGCATATTCTTCTTAAAATTCTGACCAAGGTATTAATTAAGCCATCATTACCCAACGATTATCTTCCGACAACTTTCCCTCAAAAGCGAGTTCAAAGTTTTCTAATGATATTTGGGCTTGCTCCTCAAAACGGTATACAAATACTAAAGTACGCGCAGCGTACTACTCGCGGTAATGCAAAGGTTTCGAGTTATTTTAAAGTTTTTTCTTGCACCTGAATATATTCCTCTGGTCTGAAAATGTATGCTGCACAACATTTTCGTGTTAATTCAGCAAGCCCTACATAGCTTGTCGGCTATGAAGATATAAATGACTATGAAACTCTACCTCACGATCCAATATTTACACTTGCAGTTGGAAAAGTAATTAACGCTCCCTAGTAAGGGATTGTCTGCAATTTGAGAGCTTGATTTTTGTTTAATTCCCATTATGGGTATGTAAATATTTATATGTTTTCTGGGAATACTAATTTTATCAAGGCAAAAACAAACGTCTACCATGAGGTAAGCATAAATGACTAATGCAAGTTCCGTTCTTGTGATTCCCGGATATCAAATTAGCTCTCAACTGTATGCAGGCTCTAGAACTAGAGTATATCGAGCAATCCGAGGGCTAGAATCACTTGCAGTAGTTGTGAAATTGCTGACATCTGAATATCCCGGCTTCAACGAATTACTGCAATTTCGTAACCAGTACACCATTAGCAAAAATCTCAACATTCCCGGTATTATTCGTCCTTTATCATTAGAAACTTATGGTAATGGTTATCTTTTAGTGATGGAAGATAGGGGAGAAATTTCTTTACGAGAATACACTAAAACAACAACTCTTTCACTTGTCGAATTTTTGGAGATAGCTATTCAATTAACTAACATTCTCCACGCTTTACGCCAAAACTGTGTTATCCATAAAGACATCAAACCCGCAAACATACTGATTCATCCAGAAACAAAAGAAGTTAACCTGATAGACTTTAGTATTGCTTCTGTGTTGCCCAAAGAAACTCAAGAAATTAAAAATCCTAATGTTTTAGAAGGAACTCTCGCTTATATTTCCCCCGAGCAGACAGGTAGAATGAATCGAGGGATAGACTACCGCAGCGATTTTTATTCTCTAGGTGTGACATTTTATGAATTATTAATAGGAGAATTACCATTTACATCTGAGGATCCTATGGAATTGGTGCATTGTCACATTGCTAAAAAACCTACGGCATTGGGAAACAGGTTTGGGGGAACAGGTAGCAGGGAAAATATCCCAGAAGTACTTTCAGATATTGTCATTAAATTAATGGCAAAAAACGCCGAAGAAAGATACCAGAGTGCTTTGGGATTAAAATATGATTTAGATAATTGTTTATATCAACTAAAAGAAACTGGCAAAATTATAGATTTTGAAATAGCCCAGAAAGACATATGCGATCGCTTTCTCATCCCCGAAAAACTTTATGGACGAGAAACAGAAGTTGTAACCTTGCTAGAAGCTTTTGAGCGTGTCACTAACGGCAATTCAGAAATGATGCTAGTAGCAGGATTTTCTGGAATTGGCAAAACTGCGGTAATCAATGAAGTCCACAAACCAATCGTGCGGCAGCGTGGCTACTTCATTAAAGGCAAATTTGACCAATTTAATCGCAATATTCCCTTATCTGCGTTTGTTCAAGCCTTTCGTGACTTGATGGCACAGCTGCTGAGTGAAAGTGATGTTCAACTAGCAGCATGGAAAACCAAAATCCTCGCCGCAGTAGGAGAAAACGGACAAGTAATTGTGGAGGTGATTCCTGAACTAGAGCGGATTATCGGTAAACAACCCCCTATCCCTGAACTATCAGGCAGTGCTGCTCAAAATCGCTTCAACTTACTATTTCAAAAATTCATCCAACTGTTTACTACCAAAGAGCATCCCTTGGTGATGTTCCTGGATGACTTGCAGTGGGCAGATTCAGCTTCCCTAAACTTGTTGCAGTTATTGATGAGTGAAGCTGGTGGTGGATATTTACTGATTCTGGGAGCCTATCGAGACAATGAGGTATTTGCGGCGCATCCTTTGATGTTGACTCTGGAACAGATTCAGAAAGCAGAAGCGCCAGTGAATACGATTTTCCTAGAACCTTTAAGGGAAATCACGGTGAATCAGTTGGTAGCAGATACCTTGACTTGTAACGAGGAACTGGCTCAACCCCTGACAAAGTTGGTGTATCAAAAAACTAAAGGAAATCCCTTTTTTACAACTCAGTTTCTCAAAGCATTGTATGAAGATGGTTGGATTGAGTTCCAGTCAGAACTGGGTTCTTGGCAATGCGATATAGCGGCAGTGCAGCAGTTAGCATTGACGGATGATGTGGTGGACTTCATGGCATTGCAGTTGCAGAAACTTTCAGTGGAGACGCAAGCAGTTTTGAAATTGGCGGCTTGTATTGGTAACCAATTTGATTTGATTACTCTGGCAATTATTTCCGAACAATCTCCTGTTGAAACAGCAACTAACCTCTGGAAAGCATTACAGGAAGGGCTAATTCTGCCACAAAGTCAAGTGTATAAATTTTATCTGAGCCGTGATGAGTCAGATAGGAATACTAAAAACATCGAAAACGTAGGCTATCGGTTTTTGCACGATCGCGTCCAACAAGCTGCTTATTCTCTAATTCCCGATAACCAAAAACAAGCAACTCATCTAAAAATCGGTGAACTCTTACTCCAAAAAATACCAGCAACGAAGCGAGAAGAAAAAATCTTTGATATTGTTAATCAATTAAATTATGGTGTTGAACTAATTACGGAATCGGCAGAACGAGAAAAACTTGCGACTTTAAATTTATCTGCTGGCTCGAAAGCGAGATTCTCTAATGCTTATAATGCTGCAACCGAATATGCTACTGATGGGATTAAATTGTTAAAAGCAGATTGTTGGCATAGTCAGTATCAGTTGGCATTAGAATTGCACAACCTAGCAGCAGAAGCAGCTTATTTGGCTGGCAATTTTGAATTGATGGCGGAATTTATCCAAAAAGTTTTAGATAGCGTTGAAAATCCCTTTGATAAAATCAAAGTTTATGAAATACAAATTCAAGCCTATGGCGCACAAAATCAACCATTAGCAGCAGTTAAACTTGGACAAGAAATTTTGAAATTATTGGGAATCGAACTCCCGGAAAATATTAGTAATTCTGACATACAGGCTCAACTAAATCAAACTCAATCTCTTTTTGCCGAACAATCTATTGAAGATTTAATTAATCTGCCTGTGATGACGGATAAAACAGCTTTGGCAGCAATGAAAATTTTATCAAACATTACGACTTTTGTGTTTCAAGCAGTTCCAGAGCTATACGTTTTCGTGCCATCGACGCAAGTGAGTCTTTCTGTTAAATATGGTAATTCTGAGCAGTCAGCTTTTGGTTATATAGGCTATGGAATTATTCTCAGTGGGTTAGTTGAAGATATTGATTCTAGCTATAGATTTGGTCAATTAGCGCTTGATGTTTTAAGTCAATTTGATACCAAAGAAATGACTTCAAAAGTGATAAACGGATTTGATTGTTTGATTCGGCATTGGAAGAAACATACTCAAGAAACCGTACAATCGCTCTGGCAGTGTTACTCAGTTGGGTTAGAAACAGGAGATTTAGAGTTTGCGGGAATGAGCCTCCGTTACTACGATACTCATCTATATTTCCTTGGTCGAGAGCTTAAGGCTTTAGCCACAGAGATGGCAACCCATACCCAGGCATTCCAGCAAATGAAGCAATACAGGTTTGTTCAACACAATCAAATTCAAATGCAGAGAGCTTTAAATTTATTAGGAGAAGTTGATGATGTCTTGTGTTTGAAAGGTGAAGCCTGTGATGAAGAGACTTTGCTTCCCCTAATTATGAATGATGGATTTGCACTGATCGAATTTTATTTTACTAAGCTTCAACTCAGTTATTTGTTTGGCAAATATGAACTGGCTCATGAATACGCAGCCCAAGTAGACCGCTACGCTTCTGGTGGTCGATCTTTCGTTATTTCTCGACAATGCAATTTTTACAAATCTCTAGTAAAACTTGCTATATTTTTAAATGTTAGTCAAGATACACAAACACAGCTTCTAAATCAAGTTACAGATAACCAAGAAAAAATGCAACTATGGGCACAACACTGCCCAATGAATGTTTTACACCAATATTATTTAGTAGAAGCTGAAAAATACCGGGTTTTAGGTCAGAATTATGAAGCAGGAGATTTTTACGATCGTGCCATAGGCAAAGCTAAAGAAAACGGCTACATCCAAGAAGAAGCCTTAGCCAAGGAACTGGCTGCCAAGTTCTATCTTAACTGGGGCAAAGAAAAAATTGCCAGCGCCTATATGCAGGAAGCTTATTACTGCTACGCCCGTTGGGGAGCCAAAGCTAAAACAGATTACTTAGAAAAATGCTATCCCAAACTACTAAAGCCCATCCTATTACAACAACGAATTAACCTCAATCCCTGGGAAACTATAGGAAACATTAGTGTTGCTCAGACAATTTCGTCTACTATCACTTCTACTACTGCCAGCCACACTATTTCCGATGCCCTCGATTTTAGTTCCCTTCTTAAAGCCGCTCAAACTATTTCTAGTCGCATCGAATTAGACCAACTCGTTACCTGTCTTACCAAAATTATTCTGGAAAACTCCGGTGCCAAAAAATCTGCATTAGTTCTTCCTGAAAATGCAACTTGGCAAGTTAAAGCAATTACTTCGATTAATCATCAACAAAATTCACCACTTCCAACACAAACCATCCTTGACTCACAATCAATAGATACTTGCGAAGATATTCCCAGAAAAATTATTAACTATGTCAAGAATACCCAAGAAACCATCGTTATAGATAATTGCCAAACAGATATTCCTGGACTAATTGGGGAATATATGATCGAACATCAACCCCAAAGTATTTTATGCATGCCAATTACTAATCAAGGACATTTAGTAGCAATTCTTTATTTAGAAAATAAACTTATAAGCGGCGTATTTACCCAAGAGCGTCTACAAGTCATCAATTTACTTTCCTCCCAAGCTGCAATCTCCTTAGAAAATGCTCAACTTTATCAACAAGCCCAACAAGCATTAGAAGATTTAAAAAACGCACAATTAAAAATAGTTCAAAGTGAAAAAATGTCTGCACTCGGTAATTTAGTCGCTGGTGTGGCACATGAAATGAATAATCCTTTGGGTTTCATTTCTGCGACTCTCGAACAAAGTAAACCCGCCCTTGCCGATATTGTAGAACACCTGGGATTATATCAAGAAAATTTATCAGAACCTGGCGAGGAAATTATTGAACATGCAGAAGAAATCGACTTGGACTACAGCCTAGAAGATTTACCTAAGATGATAGATTCAATGGTGATGGCTTGCGATAGATTGAAAAATATTAGCACAAGTTTGAGAACTTTCTCTCGTGCTGATAAAGATTACAAAGTAAAGTTCAATATCCATGATGGGCTAGATAGCACAATTTTAATTCTCAAACATCGCCTCAAAGCCAATGACAAACGTCCAGCAATTGAAGTTATCGCCGATTATGGGGAAATATCACAAATTGAGTGTTTTCCCGGTCAATTAAATCAGGTATTTATGAATCTTTTAGCTAATGCCATTGATGCTTTAGATGAGTCTAATGATGGACGGAGTTATGAGGATATTAAAGCTAATCCCAACAAAATTATCATTAAAACTCTAACTGAAAATGAACAAATCAAAATATTAATTAGTGATAATGGTAAAGGAATGAGTCAAGAGGTGAAAACACAAATATTTGACCATTTATTTACTACTAAAGGTGTCGGTAAAGGTACTGGTTTGGGATTAGCGATTGCTAAACAAATTGTTGAGGAAAAACATGAGGGTTGCCTAGAAGTAGAATCCGAGTTGGGAAAAGGTACGTCATTTTATATCAAACTGCCAATAATCAGTTGAATAATCTCATTGACATCAAAATAACCAATAACATGATGCGGTGGTGGAAGGAACGAGTTTAGTAAGATGAAGCTTTTTTTAGTCGATGAGACACCAGCACGAAGGCGGGAATCCGTTTTTAGCTACAAACCATCAAAAAATCAGGAGTCAAATAAATGTTGGATTGTATTGTAATTGGAGCTGGCCCAGGAGGTCTAGTTACCACCAAAGAATTACTCGAACAAGGACTCAGCGAGGTCGTTTGTTTGGAGCAAGCAGAAAGTGTCGGAGGCGTTTTTGCCAATACCTATGACAATTTAGTGCTAACTTCCTCTTGCACTTATAGTATGTTTTCGGACTTTTGGATGGGTAATGGAAACCAACACAAATTTTGGACGAAGAACGAAGCTGTTGACTATTGGAAACGATATGCCAAACATTTTGGCGTTTTGGGTAAAATTCGCTTCAATTCTAAAGTTGTTGCGGTGACTGAGCAAGGTAATCGAGGGTGGCAAGTTCAACTGCTCTCTGGAGAGACTTTGCGCTCAAAACGAGTGGCATTGGCGATTGGCAACAACAGTATTCCAAATTATCCCCAGTGGAAAGATTCATTAACTGAGGTGGAGTTTTCTCATTCCCAAAAATATCGCAATGCAAGTAACTTTGTAGGCAAAAATGTATTAGTGGTGGGCGGAGGCGAGTCAGCTTCAGACATAGCCCTAGAAATATCTGGAGTTGCCAAAAATTGCTGGGTTAGCCTTCGTAATTCAACTGGGTTTGTAGTACCTCGCAAGAGAGGCAAACGTGCTAATGACATCAGTACTAATAGAGGTATATACGGATTGCCAAGAGAATATGGTCATACTCTGAGTAAAATTATCTCTCGCCAGTGGTCGAGCTACAAAGATCCAATCGAGAAAACAGCAGTTAGGCTGAACGAGAAGGTCAAATCTCGAAATGGACTTTGGGGAACTTATGGAACTAAAACTTATGCCTTACCCAAGGCAATCGCCCATCATGGGTGTAAAGTCGTCGGTGAAATAATCGGCGTAGAAGATGGGGGCAGAACGCTACTGGCTGTCGATGGAGAAACCCTGCATTCGGTAGATGCCGTAGTATTTTGTACTGGCTACCAAAACTATATGTCTTTCCTTCCCGAAGAACTCAAGAAAACTGACCCTCGAAGTCTTTACAAACATATGTTCCATTCCCGGTATCGAGATCGGATAGTTTGGATTGGCTTGGCACGTCCGGGGTTCGGTAGTCAGTTTCCAATAATGGAAATGCAAGCCCGATTGTTTAGCTTAATCTGTACTGGCGAAAAAACTCTTCCTGCTGCTGTCGCAATGGAGAAAGCCGCATCTGTAGACCGACAGAAGTATTTACAACAGTTTGAACATAATGCCCATCGCATCCGTAGTTTGGTTGATTATCATATTTATATGGATGAACTAGCCGATTTAATTGGCTGTAAACCTCCTTTGTGGAAATACTTTTTCTTACATCCTCGCCTCTGGTTACGTCTGGTATATGGTGCGACTCAGGCAACTCAGTTTCGTTTGCGAGGTCCAGGACAGAAGGAAACTTGGGCTAAAGAAGCGATCGCTAAATTACCGGTTGTTCAATTTAATTATTTCTTTCTAGCTGGTCTAAGAGGTCGCGCCATCTATAGCTTCAAGGCTATCGTTAAGGGGATGGGACTAATCCGGGAGCAACGCGATTTCGTAAAAATGAGTGCGATCGCCAAGATTCAATCTGCGTATCTAAAATATTTAAGACATTAATTTGTTTTAGCTGACAATCTTAACGGCACAAACGTTTTCGCCATTCATCTTTTTGGCTAAGTATTATGAAAATATACTGAACTTATATATGAAGATTCACTGAAAATACATAAAAAAAACGATACAAATTCAATAATTTTCTCAGTTGCCAAAATACTTCTTTATAAGACAACATAGAAGCATGAACGCATATATTTTCGGCTAAATAAGCAAAAAATTTTGGTTCTCCCGGAGAAATTGGCTATGATAAATTAATCATAAAAAAAGGTTAAAATAATTGATGTAGCAAGGTTATAGCAATATAAAATTTAAAGTTTAAATTTTAATAAAAATGTGCTTTTTTTGTCTAAAATCCTTGCTATATCACAATTAAAGTTGGTATTAAATATTAATTTACATAACTAGTCTGGGAGACCTAAAATCTTTCAGTAATTTTGAAACAGAATTGAGCAAAAACTCTCAAATTTAAAAAATTAAGGTATAACATGTTAACTTTACAATCGATAGAAAATGTTGAGGATGTAATATCGTCAATAGAAAATTTTGAGGATACACTATCTTCAATAGAAGATGTTGAAAATGCACTACAGTTAAAATTTCATAAGCAAGTAACTGAGCCGGGCATAAAGAATCCAGTCAAGTTTTTGCAAAGATGGTCATATCTTTCTACCCAAGTAACACGACTTGCTGGAGCTGCATTGAGTCGCGCACATCTCGCAGACATTCAATACTTATTAGCAGAAATTGCTTACAGCGAGTGTGGTCTGGGAAATAAAGACGAAACTCACAGTAAACTAATGATTGAGTTGATTAATAAATCTCCTCATGCTGATGCCATTACTCAAAGATTAGATACATACTTCTTAAATTTATTTGAAGAAACAATTCTCGAATTATCCCAGATGAGCCAAGAAGAAGCAGTTGGATTTATTGTTTCCCTAGAAGCTCCTGCTTATCAAATTCTGGAATTGCTAAAACAAACTTCTATAGCTGTTGGTATTTTTGAAGTGGACTTCTTAAACTCTGAGTATTTTTTGATTCATGATGCTATGGAAAAAGAACACCAAAAATCATGTAATGAATCAATGCAAGTTGTTGTAGATAATGGATTGGAATTAAGTAAAATTTACAAGGGCGGCGAGAGAGGAATTAAGTTTCTTGTTGAATTCCTTGGGTGCTGATTTTTGAGGTAGACTTCTTCAACTATGAGTATTTTTTGACTCATACATAATGACTCATGACACTCGATTTTTGGGTAAAAACAAACGGTACTTGGATCAATGCCATCAGTGTTATTTTGGGTACAGCTGGCGGTATGCTCTTGAAACACCGCCTTCCCTTGAGAATGCAGCGTATTATCACCCAAGGAGTAGCGTTGATTACCCTATTCATTGGTTTTCACATGGCTCAAAGCCTGTTACAAGTCAAAAATAGTCGAGTTGATGGGGTCGTATTAGGACTAGTTGCCATCATCATCGGCGGGCTGTTGGGTGAATGGTGGCATCTAGAAGAGAGGCTTTATCGGGTGGGGGAGTTTCTGAAAGTACGCTTTCAAAAAAGTGGCTATTTCACAGAGGGGTTTGTTGCCGGTAGTTTGCTATTCTGTGTGGGACCAATGGCTTTAATAGGCAGTCTCAACAACGGTTTAACCGGGAATAACACTCTGCTGATATTGAAAGCGACAATGGATGGTATAACTTCTATAGCTCTTGGTAGTAGCTTTGGTATCGGAGTCGGATTTTCATCTTTAGTAATTCTGGTTTACCAAGGCGGTGTCTCCCTCTTAGCTGGATTTTTAATTCAATCTTTACCAGATCCAACTCACGATCCCCACTTATTGCTGATTACTGGTGTGGGTGGTTTAACAGTTATAGGTTTGGGATTTAACTTATTAGAAGTGTCTCAGGTGAGAGTAGCTTCCTTTCTCCCAGCCTTGCTCGTAGCACCACTTCTCTATTTTTTGTGCCAGTAAATCGAACAGTTTTTTTTATCAAGGGTGCAAACTGGAAGATTTTGTGGCTATAGAATAGTTAGACTTAATACATATTTTTGAGCCAATCACTACACCCGGATTTCTCGCAAATGAGAAATCCGGGTTATATCATGTTCGGATAAACAGTTCTCAATGCGATTAGAACGCTGAATGCTTCGCACAACAAACAATGACAATTCTGAAGTGCCGAATGTGGGCGATTTTATAACTGTGGTAACTGCGCTATTGTATCCACATCTTCAGGAATTAACAGCTCGTCGCCATTTTTCTCAAATTCGCATATAGATTCTGGTTTTACGGGACAGGTTTTGTTTTTAATGGGATTTTCGCCGACAAAAAGCCAAGTTAAATTGGTTAATTGGGAAAGCGGGGATAAATCACCTATCTGATTTGATTCAAGGAAAAGAAAATTTAGGTTAGTTAATCGAGATAGGGGAGATAAGTCGCTGATTTGATTGTAAGAAAGATAAAGTTCTTTTAAATTAGTTAGCTGGGCAAGGGGTGACAAGTCGCTAATTTTATGGGACGAAAGGTCTAGTATTTGTTTTTTTCTGAGTTTTTGCTGGGCGCGATCGCAGTTATTTGTACCAGCTTTTCGCAGTAAAACTTTAACTGTATATTTTGTTTGCTTGGGTAAGCTCTCTTTGTGCTTACACAATTGAGTAAAGCTGGGAATAGGTTTTTGGTTTCTTTTTCTGGGAACAGCTGCAGTCGGTTTAGCATTTACTATGGTGATTCCCATCAGTGCTATACAAACTAAACGTATAAATTTCATCGGTTTATAGTATTTTTTAATATCAACAAGGTTATTAAACCCAGCAAAATCGAAATAATCAAGTTATATATGACACTTTGTATTATTTCTTGACAGTATAATTATTAACTAGATAATACTGATATCCGATTTATTTAATTCTTACGAACTATCTAATACCATTTCTTTATAAAGATGCGCCCCTATGAAAGCCCGTGTAGACGGTGAATCTAGTTGGGGGTGTCGGTTTCCATCCCCCAAACTAGTACTCTGGCAAGCCACAATTGCCGGGTAAGGGCAGGCAGGGGGAGCAGGGGAAGCGGAGGGAGCAGGGGGAGAAAAAACTTTTTATTTCCACGCTAAACCCAGCAAAGTTCGCTTGGCGAACCACTAGTGTTCGCGGAGCGTCTCCCGGAGGGAGATACCCGGAGGGGCTTTGTTTAAGTAGCCCCACTCTTATAGAGTGAGGGCTATTGAGCGCAGCCTCATACAGAATTGATATAAGGTATTAATATTTTTCTATTTCTAATTCCCAAAAGACATCTCTCCAAAGCTCCTTCCTCACGGGAGAGAGGCTTTTGAATCCCCATTCCCACATCTGGGAGGGGTTAAGGGGTTAGCTTTTAGGGATTGGGAATATAAATATATTGCTTTAAATTCTCTAAATCCTTTTTAAAATACCCATAACTTGATGCTTTTGCAAAACTCTTATTAAATGTTGTGCTTGAAGTTTGTATAAAGGTACTTTTAAAGTCTGAGGTAAATTATTGATTAATTCTCTGGCTTTATCTAAAGGGTAGTTGGAAATTTTGGCAATTTGATTTGCTCCTTCAAATTTGGCTTCTTCTGTATTGGCGCTTTGAATGACTACTTGCCAATTTTTGGGATAAATACCAATTCTTCCTGCTTCCATTCTTTTCAACCCATCGATGGTTGCAAGAACAGTTAAACTGATACCTGGTTCTATTTGCTTGTATGCTTTAGGCATTAACTCTCCTTGTAGCGGTGGTTTTTGATATAAAATTGGTACTACACCATAGCCGTAAGCAATTTCGGAAAGCATTAAACCATTTAAAGTATCAACTTCAGTAAATTGATATTCCGTGACTAAAACTGTTTGGTTGTGTAAACGGAATAAGTCAAGAATGTTTTCACCAAATGCGGCTCCGGCAAAGGCTTCTGCTGCGACTGCGTAAGCTGATATTATTTGAGCTTTGGGTAATATTTGAGCCAAGTTTTCACTCAAACGCTGCCCAAAAGTACGAATTACTAAATTACTTTTGGGGTTAATTTTTAAAGCTTTTAGTCCCATTTCCACGTTTAACATTTCGTCTTCGCTAGTAGCAATTACGCTTTTCGCTGTGGAAAGATTTACTTTAGTCAAAGACTGGTTTAAATCACCTTTGAATAAAGGTATATCTGGTAAATGATTGTCATCAAAGTCGTCTTCTAAGGCAATCGCGACTAAGGGTTGATTGAATTGCTGTAATATCTTTGCTGCTTTACTACCAACTCTTTTAATGCCAATAATTACTATATGCTCTTCTTCGGGAACTGGAGAGCGTTTTTTGGAAAATAGAAATTTAGTTGATAAGAGTTTTTCGGTAGCCAGCGCATATAATACCCCAACAAAAGCTGTTCCAGCTACCGCTAACGCCAAAGCTAAAAATTGCAAAATTATCGAGTTGGGCTGTACGCTATACAAAAAATCTGCATATCCACCCAAGAGTAAACTAATTGTCAGATATAAAGGATTTACAGAAGTCGAATTTCCTACTAATACATAAAAGAGTATGGTTCCTACAGTTACCAAGCCAATGGTTACTAAAATTGAAACAATTACCAACCGACGAATTTGGGAACCAGAATGCCAATAATCTAAAAACTTTTTTCTAATTTTAATTTGATTAAAAATATTTGCTGGCTCTTTCCATATTTGCTTTTTCTTGGGAGTATTATTAATCGCACCTTTTTTTTGTTTTGATAACAACCTATCAAATTGTTCTACATATATCAGAGTCGAATCTTCCTTAATTACTGTTTCAGAATCCCAATCATAAAAGCAATTAAAGGCATCATATTTATTCGGTAAATAGCACAGTAACTTTCGAGAGCCAGAATTTATTTCAAAAAGCTGACGACGGTGAAAAATATCTCTATCACGAACTTTATGCTGAAAGACTCCCAGCCAATTATTATTTAAATTAAAAAATCCTAACGAATCTCCCCCTAAAGCCGCAAGAGCAAAGGATGCAGCCGATAAATGAATGGGATCGTAACCAACATAATTGCTTAACTGCTCCTCTAAAAGTTGATTTAAATTTTCCTTCGTCGAACGAACTACCAAGCGAGCATTTTTGTTAAGTTGTCTGACAGCGATGGCAGTTTCGGCGTTAATCAATTCGTCGCTAGTGACAATCAAAACAGCACGGCAAAGTTCAATTTTCGCACGCTCAAAAGTGCTATTTTGACGACAGTCACCGATAATTAGTTCATCGAGCAATTTATCTACACCGGGAATTCTCCAACTTTTCGGCTCTACTAACTCAATTCCAACCACCTTTACCCCGAATTGTTTCAAAGCAATTACGCATTGCTGCCCCAATCCTCCTAAACCACATATTAGAAAACGCTCTTCTGTAGCAGGTTTATGTTCTCCCATGACTTAATTTTGGATTCTATATTAGTTAAGACGGTTAAAATTTACAAATTTTGAAACAGTTATTATTCCTTATAAAAAGAAATAGTAAATCATTAGAATGTATTTAATATATATACAGTTGATTTATCGGTATTTTACGAAAAAGGTTTGATACTCATTCAAACAGCCGCAAAAATCATAGCATAGTATATTAATATACTTATAGCTATACGCCATGACTAAAGCAGTAAAGATAGTTAGAAATTTGATTATAGGTTTTGCTTTAATTACAATGATTTCAGCAATCGGCGTTTATGGTTTAATTATTTTCGTCTTTTCTGCCGAGAATGTAGAGGAATATGAAAGTAAACAAGCGCTATCAAGCCTACAAATAAGGTTTGCAAAAGGAAATATTTCTAATGCTTATGTAGCAACTTCTACTTATTGGCACGATTATAATTATTACGCTCGTTTTAATGCAAAAGCAGACTTTATCGAGAAATTTATCGTCGAAACCAAAAATAACAGAAATAAACTTCAAGAAGAACCTATAGATTCTAAGGCTTGCCAAATAATACTCTCTGAAAAAATTAGACTTTCGTGGTGGAATCCGCAAGAGTTTGACGTAGATAAATGCTATTCAGATAAGAATATTTCACCTGGTACCTTTTCCGTATTGCTTTATCATCCCGAAAGCAGAACTGCATTTTATTACCACCATAATAATTAGCATCTCAATGCAGAATATGTATTTTGAAAGAGGTGGGAGAGGGGATAGATTATAGAAGAAAAAATTCCCATCACTCCATTACCCATTACTCCATCACTTCATGACGTATCTGGATTTTTCCCATAAACCCAAACCTCGCTGTTTAGCATTAGCTTCTGCTACCAAATACTGGATTCTGCTTTCATAACAATTTTGCTCTACAGAAGTTTTATCTACAACAGCTTTACCTTCTTTAACCATTTGCAGATTTATCGATTTATTATTTAAAAATACTTCCCCAACAATTTGCGATTCCTTATAGGTATCTGCAAACCTAATAACTATAGGATTACCATTCGGTAAAAGTTGTTTCAATCTTTGATTAGCTTCATCTCTACGAGATTTTCGAGTTGGTATGTGAATGCAAGCCATCTTTACAGTGGCTACTTGCCCGCTGACATTTTTTGCACGAATGGTTTCCCCATCTACCACACCCACCACAGTTGCGAGTATCAACATTAATTCTGTTAAAGAAGTCATTTTTTATTTTAAAAAAGAATATAAGTAATACCATGTTACTTTAATAACTGCGTATTTGGTGAAGTTTAACTCATATTTGACGCAGGGATTTTATACTCCCATTACCCTCTAAAATTTTCGATCAAATTTCTCTCCATAAAAATGCGGAATTCTTCTGAAAGAAATTGAAGGTTACTAAGGATGGCTGATTGTCTATTCTCCTCATAGAATAGAGTTATTCCGGCAGGGAGTATGATTTTTTTTAGCTCAAATTTTACTGACTAGGATTTGTATCGTTAGCGTTATCAGAAAGCATCTGTGGCATTTAATTTTCGAGGCTTCTAATAAACGTCTGCGTAAAAACCTTTGTAGGAAATAAGAAATTAAAGATGAATCAGAATCAACCGAAATTCAACTACGGTGAAGCTCTACAAAAGTCTAATCTTTTCTACCTAGTTCAGCGTTCTGGAGATTTGCCCGACGATTATGTTATTTCTTGGCGCGATGATTCTGCTGTTAATGACGGTGCCGATGTCAACCGCGATTTAAGTGGTGGATACTACGATGCAGGCGACCATGTTAAATTCGGCTTTCCGATGGCAGCCTCAATGACGATGCTTGGCTGGGGCGTAATCGAATATACCGAGGGCTATAAGAAAGTTGGTCAGTTTGACAATACCCTTGAGAATATCAGATGGGGAACTGACTATCTTCTTAAAGCATACGACGATAAAGGAACTGCAACTACATCAGATGATGTTTTCTGGGGGCAAGTAGGTAACGGTCAAATAGACCATGCTTACTGGGGAGCGCCTGAAGACATGACTATGCCTAGACCAGCTTTTAAGGTAGATGCACAAAACCCCGGTTCGGATTTAACCGCAGAAAGCGCTGCTGCATTAGCTTCTGCTTCCATTGCTTTCCGCTCTACTGATGCAGCTTATGCCGATAAGCTCTTGGAGAAAGCTAAAGGGCTTTATGAATTTGCGGAGCAATATCAAGGTGCATACACTGATTCCATCACTAATACTCGGAGTTTCTACAATTCTTGGAGCGGCTATGAAGATGAACTGGCTTGGGGAGCAGTTTGGTTGCACAAAGCGATTCAGGCAAACGGCGAGACGGATAGCCAATACCTAGATAAAGCACAAAACTACTACAAAGGTATTACTCCTGGCTGGACGCATAATTGGGACGAAAAATCTTATGGTACTGCTATTCTATTAGCTCAACTGACAGATAAATCTCAATACAAGCAGGATGTAGAAGCTTGGTTAGATAACTGGGCAGATCCTAATGGTGGCATCCAGAAAACTGCTGGCGGTTTAGCCTGGTTGGATCAATGGGGTTCGCTACGCTATACAGCAAATACTGCTTTTTTAGCCGGTGTTTATGGTGACACTGTTAACGATAAACAAGGAAAATACACGGAGTTTTCTGAAAGCCAGATTAACTATATTTTAGGAGACAATCCTAATAATTTTAGTTACATGGTGGGTTTTGGTGAGAACTACCCCCAAAATCCTCACCACCGAGCAGCTTCTGGTACGACTAATATCGGTGACTCTGACTCTAATGAATACACTCTCTACGGTGCATTAGTTGGTGGTCCCTCTGCACCAAATGATGATGCTTATCAAGATAAGCGTACCGACTATATCGCCAATGAAGTTGCATTAGACTACAATGCAGCTTTTACCGGCGCTCTAGCACGCATGACTGAGCAATTCGGTGGGGAAGCACTGACTGAAATTCCTGGTATTAACCTTGATGGAAGTACTAATCCCAACGACTCGGGTGGCAATGATAATCCCGACGTAGATAATCCCAACGATTCGGGTGGCAATGATAATCCCGACGTAGATAATCCCAACGATTCGGGTGGTAACGATAATCCCGACGTAGATAATCCCAACGATTCGGGTGGTAATGATAATCCCGACGTAGATAATCCCAACGATTCGGGTGGTAATGATAATCCCGGTGGAGATAATCCCAATGATTCGGGTGGTAATGATAATCCCGATGGAGATACCGGAACATTAAAGGATGTCCAATTCTCTGTAGTAAATCAATGGAATAATGGCTTTACAGGCAAAATCAAAATTACTAACAACAGCAATCAAGCTATTGATGGCTGGGAGTTGGAATTTAATGCTCCTTTCGAGATAAAAAACACGTGGGACGCTAGTATTGAAAGCGATGAAGGAAACGAATATGTCATCAAGAATCTCGGCTATAACCGTTTAATTGCGTCAGGAGAATCAGTTGAGTTTGGTTTCCAAGGTAGTTATTCTGGTGATATCAATTTAGCTATTGATAATGTAGAGCTTAATGGAACGGGAAATCTTAGCAGTGCGGTTGGTTTAACCGATAGTAATCCAATCGTTCCAGCTACTGCTAGCGATAACCCTGATGAAAGTAGTAATCCAATCGATCCAATTACTGGTAGCGGTGATAATTCCAATACAGATAACAATCCAACCGATCCAATTACTAGTGGTGGTAATCCCGATTCAGCTAATGAAGCAATTGATAATGTCGTTTTCTCTCTAGTAAATCAATGGAATAATGGTTTTACAGCCAATGTAAAAATTACCAACAACAGCAATGAAGTTGTAAACGGTTGGGAATTAGAATTGAACACTCCTTTTGAGATTAAAGAAATCTGGAATGGCAGTATTGAAAGTCAGGAAGGAAACGAATATCTGATTCAAGATGTGGGCTGGAATGCCTCCATTGCACCAGGCTCATCCCTTGAGTTTGGCTTTAATGGTATCAATGCCGATGCTATAAGCGAGCAGGATATTATCAACCAAATTAGCTTTTCTTCGGATTCCTTGCCAATTTCTGACTCTTAGATGTAACAGTTTTAGATTTGTAGGGGAGGCTCTCTAGCAGTGTCGTAATCCAACATTACTCTATTCATGTTGGGTTACGGTGCAATTTCTAACTTACTAGTACTACACCACATTAATTTTGAGGAGTTATAAACTTTCTTTTAAAAAACCGCAGAGAGCGCAGAGGGCGCGGAGGAAGAGAGTTCAGAGGATTATCTTGTTAAAAGGGAAATTTCTGTTATCCCTCATTACTTATGTGGCAGAGTACTAGTACTCAAGCAAGCCAATATTGGCTGAGGTAAAGGAGGGGGGAGAGAGGGAAGAGGGGGGAGAGAAAATTGTCTGTATTAACGATACATCCTGCAAAGTTTTCTTGGTGAAGTACTAGTCAAAAAATCATACTTATAAAAGCACTTAACCCAACCTACTGAGCGCGTTGTTAATCAGTTCCTCTACGGTAGAATGGTTCGCAGTTATTTTTGAAGTAATCAGAAAAATAACTTTCAGAACTATCAATTTTAACGAAATCCACGGGTGGATCTGGTATTTCAATGTTGCGAATGCACAAGTCTAAACCCGAAATCACAGCATCCCAATCACCATAATCTTCGATAGCTATAAGGGTATGAGGTTTTTCATCATATGATGGGTCGAAAAAGTGAGCAAGATAAGCGGATTTGACCGATTTAAACTTTGTTAAATAATTTTTTAATACCTCAACCAAAGCCTTGGGATAATTTGCGGGCTGACCAATCATTATTTCGGTTCCACTTTGGACTTCCCTTGCTGAATCTTGGTTAAAAATACTCCCATCTAAAAGAGATGCAATTTCTTCGACTGTAAATTCTTTTCCACAATCATTATTTGGATTTAAAAGTAATTTTTGTCCTTTAGTCATCTCAAAGAAAGTCCTGGCATTAAAACTAACATAATCTGATTCTTCCCTAATAGCTCTTTGCAAAGCTGTAAACGAACTGAAAAATGGTAAATAAACATTACCGTTTATTTCCATAGACTGGATTGAGATGGATTCTTGCTCACCCGCAATTCTTGAACCATAGCTTGGCTTTGAATTAGGGGGTTGTACTAAGAAAATATCGGATTCCAAAATAAGTTTGTAAAAATCATTACGAACAACCGGGTCATTGGCTGCCTTAACTAAAAGTTCTTCTAATTGATTACTAGGATTAAATTCCATTTAATTAATTATTTTAGATATTGAAGCATACTTTAGAATGCTTATTTTACTTACTAAAATAGTCTATAAATTATACTTACGCCTGCGAATTATTTCGTATATTGGTTTAGACAGGAAAATAATTTGCTTAGAAACGGTTGGTTTGAATTCTGTCGTAATCCAATATTAGTAATTTGAAACAACCACAAATAATTTTGGATTAAGGTGCAATTTCTTATTCTTTAACTAAAAACCATATTTATCAAAGCACTGCGAGCGTAACCTACAATTACTATTCTCTTCAATAATTTTAAATTATCGAATGGTGCGTCACGGCATCAACAAATTAACTCTTTCTTACCAAAGTTATTCAAGCCGTGGCACAACGGCAATATTGTGGGAAGAAAATCTACACCACAATTTGCCTCCCCTACAATTACCAATTACCCATTCACCAATCCCTTAAATTTCTCATATAAAGGCAATTGCTTCAAAATCGGGGTCATTTACAGTTTTTAGGTTGGGTTAGGCACCAAAACTAATTTGATTAAAAACGATAACTTTAAATCGTGTCCTAACCCAACATCAATCATTTGAAACAATCACAGATAATGTTGAGTTACGGTACAATTTCTAATTATTTTAATTTGATACAGGATTCTCAACTAGCATTTCCTTCACATATCGCTCAATAACCAATCGCTGTTCTTCGCTTGTTAGGCGATTGGCTTGAATCAGCCAGTCAAGACTAACGCCATTTACCAGTGCTAGAAGAGCGTTGGCTTCAATACCAGGCTTTATATCCTGGCGCAATAAGTTAGCTGCTTGCAACCCTTCAAGCTCCTCTACTAACATCTCTCGCAGTTGTGCTGCGCTCTGCTGATGTTCGCTCATCAGGTTTTCCCGACCAACGGCATATCCTAAAAATGCTACCCAGACTCTCAGTATATCTTGCCGCTCTCTATCTAACGGTAAAAATGCTGAGAGCATGGTGACTAATCTTTCTATTCCCGAAACAGAATCAATTGCTTCTGCCATAAAAGTTTTGAGTTTTTCTGTCACCTGATTTAAAGCGAACAAAATTAACTCTTGCTTATTGCGAAAGTAATGAGTGACAACCCCTGTCGTACAACCCATTTCCTGCGCGATCGCCCTCATGCTAGTACGGTCTAACCCCTCCCGCACAATTACTTGCCAAGCTGCTTGCGATACCTCAAGACGACGCTTTTCCTGGGTCATAGATTCTCAAATAATTCTTCAACTACTAGTTCTTGACAAACTATCATAACAGTTGTTATATACTAAATATGCATAACAACTGTTATGAGGTAAAAGAATGCAGACAACGCAGCGACAACACTACAAGAATCTCTTTACCGATAGTCCTACTCCTCGTTCTGGCTGGGTAGGTATAATAGACCGCTTTATTGGACCAGGAGCAACCCCGGCTGAGTTATGGCTGCAGTTTTTACCAGCAGTCATAGCTGCAATCGCAGCACCTGCTTATGCTCTCACGCTCTCCGATTCCTGGACAGGGCTACAGCTTGGTTTGATAGTTCTGCTGGGGTTTGATTGTGTTGGTGGTATTCTCACCAATGCTACTGCTTCTGCTAAACGCTGGTATCACCGTTCTGGACAAGGGTGGCAACAACATATGATTTTCGTTGCTTCTCATACGATACATATCAGCTTGGTTGCTTTGCTGTTTCGGGAAAGCGATTGGGCGTTTTTAATCGTTGTATCTGCTTATTTACTGATAGCATCCATAGGGATTTTGCGTTCGCCACTTTATCTTCAGCGTCCTATAGCGCTAGGGTTTTACGGATTAGCTTTGCTCGGCGATCGCTATCTATTTTCTCCAACTCTAGGTTTGGAGTGGTTCTTACCTTTTTTGATGTTGAAGCTTTTGGTCAGTCATTTACTTGCAGAAATTCCGTATTCCTCTGATGTCGATAGGCAGTATTGAATGCATCCACATTTTTGATTTTGGGAAAATTATGATGACAACTTTTAACAAATATGCGATTGCCGGACTTTTGGCTTTATCATCCGTTTCCCTAAGCGTGTTAGTACCCGGAGGACCGATTGAAACCCGTAGTTTTTCTCATATAAATCCGATTATTCTAGGAGTATTTAATACCTTCTTAACTTCCCTGAGCATTATTAGTCTATTAATCGTCTATTTTGTTTTGAAGCAAAAGTACTGGGCATCTATAATATCTGCGGTTTGCGGTGTGTCCTATTTTCTGGTGTACGGTTTGGATTTAGCTCGTATATTTCCTGTTTCTCCCGATAAGCTGCTACGCAGCTAAATTGAATAAACAGCGTTACCTTTATTTTTAATCTTGCGGTCCCACTTAATAATAAGACCTCCTTGATTTAACAATTTATTTAATAATTCTTCAAGCTGTTCTACTGATTCAAATAATCTATGAGCTATATATTCTTTCGCTGAGTGCCAAACTAATTCAATTAAATTATAATCTGGACTATATGGTGGTAAGAATTCCAAAATTATATTTGGCATTTCTTTTTCAATTTTCTCTAAAATATCTTTTCTTTTATGAAAGCTGGCATTATCTAAAATAATCACTATTTTAGCTGCATAATCATTAAAATATTCAATTTTATTTCCTTTTTCTACCCATTCTTGTAAAATAAAACTATACAAAAGAGTAAGTTGTTCATAGAATACATCCGCGTCTCCTTTTTTGATGACGAAATTCATTCTTTTTTTATCGTGATAACGTAATCCTCCCATGATATTTACTCTTCCTCTTCTTCTTTGACCGGTTACTTTTTTTCTATGACCTTTTTTACCCCATGTTTTTCTTCTTATAACCCTCAAACTGAATCCGCTTTCATCCCAAAACCATACCTGCAAACGTTCTGGGGTTTCTTTTGTTATTTTTAAATATTCGGATAATTTCTCTTTAAATATCTTACGCTTCTCAGGATTTTGTTTATCCTCCAAGCTATATTTTGCCCACAGGTAAACGAACTTTTTTCTTGATAATATTCTCCTGACTTGAGAGCCACTTAACTTAATTCCTGTTAACTTTTCAAGATAAGTTGCTAATCGAGCAGATGTCCATCGACCAAATTCATATCCATACTCTGACGGTTCTTTATCAACTATTTCTAATAATAAGTCTTCATATTCTTTAGTTGCTTTACGGAAATTACCCTCTCTTCTTCCATCTAACAAACTATCTAAGTTGTCTGGGTCGCCATGAACTGCCCAGTATGCAACTGTTCCATATGCAATATTTAAAAAATCACTAATCTCTTGATATGTTTTTCCATCATTCATCAATAATAAAATTAGAATTTTTTCTCTTACATAAGGGTTCTCATACTCTTTGAGGGCTTTTAGCAGTCGTTCTCTCTGCTCCTTAGAAAGATGATTTTTGGCTGGCAT

Protein sequences of DBSCAN-SWA_4

>NC_019678|6504720:6556934|6507758_6508169_-|WP_015121139.1|DBSCAN-SWA
MVDIKVQLSAKVSGGPQASLNEDIKVEAYNKIEVAIQPGDTDKVVNVAQGDKGEISFLLITSNLYSSEEKLTYKVGDKEIQLDQPQIFLGTGAVSLLGENLNQIQFSNKHEKATEEGKPDPNKADIEILVGRDATP
>NC_019678|6504720:6556934|6530863_6534829_+|WP_015121152.1|DBSCAN-SWA
MKGDFTRFTFKPEKHYTSVLMQQGRVQLDADWNEQANIHAYFNQSIAQDMIGNSGVAKTSGGFEIQIIDNSTDLLITPGHIYVDGILCELEGNLFDVTERVNIQSNQKQIELKSIYIDNRILEKGEWLEVELIDKNNNNQLSKKQLQIQEVDKKNQLLTFRNTENIDGDIKQLRRLTTYNNQPDYPQEIQIDSKDNSKTFVEGKNYLAYLDVWQRNISAIEDKDIREIALQGSDTATRTKTVWQVKLLELENNHISKHNLHTSTKWEALKKRNVYLNVDDTNASGGEGGWKNQLYRVEIHKGNQEQDNSAEVTFKWSRNNGAIVFPIKEIKSDYIEVSNFSRDISDSFKSEQWVEITNDVRELQGEPGTLVQLRNISQNKLFYNPATIVNDSSDSSTFPQGHNLKIRSWDSNHSNNQDAIPLKSSDRKVVLENGIQLEFEGDSFKTGDYWLIPTRAVKVNKHHIQWTFDSSDKPIPQPPEGIEHHYSALALLSYQNNQLNLVEDLRETFPSLSNCLDKTGDIMTGALEIQDNLYITGKSNQDNQYIPGKVGIGTKEPQQRLVILDKDDIKGRVAIGFNDTEQTAALAIKENVGIGYFNIPKTTALAINGKVGIGTKEPQQALVILDKDDIKGKVAIGYNKTGQKAALAIKDKVGINTILPKSDLSVLGNVAIGSTNYTEIANAPDNGLIVEGNVGIGSPNPTSAKLEVNGDVKITGDSIKNTNNFKIIDTQNQDWLNINPDAEYPGIALYNPVAISKGGLVIGELTKISDGELKVSKNTLLATTSGKVTIGNLQQVSENTLLEVAGNTIIGSSYIGDRAAPENGLLVEGKVNIGDTPKNNQPAENAQLYTQGDAYISNKLYTTDLSVTGNIELGESTQLSIAELEVSKSAFLATASGKVGIGTQQIHNNTFLGIAGNTTIGSSYINSKAAPENGLLVEGKVNIGDTPKDNQPAEDAQFYNEGDAYINGTLYTKDLSVIDNIEFVESTQLSIAELKVRKNSFLATTRNSQVSIGSQRKPNTKTLMGIAGSTTIGESYINSKAAPENGLLVEGKVSIGGTIPRNNQQAEDAQIYTEGDAYINGTLYTKDLSITDNVEFAESTQLSIAELNISKNAFLATTKNNQVSIGTQQKPNAKTLMGIAGSTTIGESYIDSKAAPENGLLVEGKVSIGGTIPRNNEARTSQLYVKGNAYINDTLLTDTIVYNQMMQRSSQQYKDNITELSIPESLQILEDLKPVKYSYITDETKRIHAGFIAEKSPEIFTSPDKTMLNSTGIIAILTNVLKEHIHTNSALNRVIANQQQEIANLRKRVNKLEEKNNKLFW
>NC_019678|6504720:6556934|6541272_6542880_+|WP_015121154.1|DBSCAN-SWA
MLDCIVIGAGPGGLVTTKELLEQGLSEVVCLEQAESVGGVFANTYDNLVLTSSCTYSMFSDFWMGNGNQHKFWTKNEAVDYWKRYAKHFGVLGKIRFNSKVVAVTEQGNRGWQVQLLSGETLRSKRVALAIGNNSIPNYPQWKDSLTEVEFSHSQKYRNASNFVGKNVLVVGGGESASDIALEISGVAKNCWVSLRNSTGFVVPRKRGKRANDISTNRGIYGLPREYGHTLSKIISRQWSSYKDPIEKTAVRLNEKVKSRNGLWGTYGTKTYALPKAIAHHGCKVVGEIIGVEDGGRTLLAVDGETLHSVDAVVFCTGYQNYMSFLPEELKKTDPRSLYKHMFHSRYRDRIVWIGLARPGFGSQFPIMEMQARLFSLICTGEKTLPAAVAMEKAASVDRQKYLQQFEHNAHRIRSLVDYHIYMDELADLIGCKPPLWKYFFLHPRLWLRLVYGATQATQFRLRGPGQKETWAKEAIAKLPVVQFNYFFLAGLRGRAIYSFKAIVKGMGLIREQRDFVKMSAIAKIQSAYLKYLRH
>NC_019678|6504720:6556934|6535684_6541117_+|WP_015121153.1|DBSCAN-SWA
MTNASSVLVIPGYQISSQLYAGSRTRVYRAIRGLESLAVVVKLLTSEYPGFNELLQFRNQYTISKNLNIPGIIRPLSLETYGNGYLLVMEDRGEISLREYTKTTTLSLVEFLEIAIQLTNILHALRQNCVIHKDIKPANILIHPETKEVNLIDFSIASVLPKETQEIKNPNVLEGTLAYISPEQTGRMNRGIDYRSDFYSLGVTFYELLIGELPFTSEDPMELVHCHIAKKPTALGNRFGGTGSRENIPEVLSDIVIKLMAKNAEERYQSALGLKYDLDNCLYQLKETGKIIDFEIAQKDICDRFLIPEKLYGRETEVVTLLEAFERVTNGNSEMMLVAGFSGIGKTAVINEVHKPIVRQRGYFIKGKFDQFNRNIPLSAFVQAFRDLMAQLLSESDVQLAAWKTKILAAVGENGQVIVEVIPELERIIGKQPPIPELSGSAAQNRFNLLFQKFIQLFTTKEHPLVMFLDDLQWADSASLNLLQLLMSEAGGGYLLILGAYRDNEVFAAHPLMLTLEQIQKAEAPVNTIFLEPLREITVNQLVADTLTCNEELAQPLTKLVYQKTKGNPFFTTQFLKALYEDGWIEFQSELGSWQCDIAAVQQLALTDDVVDFMALQLQKLSVETQAVLKLAACIGNQFDLITLAIISEQSPVETATNLWKALQEGLILPQSQVYKFYLSRDESDRNTKNIENVGYRFLHDRVQQAAYSLIPDNQKQATHLKIGELLLQKIPATKREEKIFDIVNQLNYGVELITESAEREKLATLNLSAGSKARFSNAYNAATEYATDGIKLLKADCWHSQYQLALELHNLAAEAAYLAGNFELMAEFIQKVLDSVENPFDKIKVYEIQIQAYGAQNQPLAAVKLGQEILKLLGIELPENISNSDIQAQLNQTQSLFAEQSIEDLINLPVMTDKTALAAMKILSNITTFVFQAVPELYVFVPSTQVSLSVKYGNSEQSAFGYIGYGIILSGLVEDIDSSYRFGQLALDVLSQFDTKEMTSKVINGFDCLIRHWKKHTQETVQSLWQCYSVGLETGDLEFAGMSLRYYDTHLYFLGRELKALATEMATHTQAFQQMKQYRFVQHNQIQMQRALNLLGEVDDVLCLKGEACDEETLLPLIMNDGFALIEFYFTKLQLSYLFGKYELAHEYAAQVDRYASGGRSFVISRQCNFYKSLVKLAIFLNVSQDTQTQLLNQVTDNQEKMQLWAQHCPMNVLHQYYLVEAEKYRVLGQNYEAGDFYDRAIGKAKENGYIQEEALAKELAAKFYLNWGKEKIASAYMQEAYYCYARWGAKAKTDYLEKCYPKLLKPILLQQRINLNPWETIGNISVAQTISSTITSTTASHTISDALDFSSLLKAAQTISSRIELDQLVTCLTKIILENSGAKKSALVLPENATWQVKAITSINHQQNSPLPTQTILDSQSIDTCEDIPRKIINYVKNTQETIVIDNCQTDIPGLIGEYMIEHQPQSILCMPITNQGHLVAILYLENKLISGVFTQERLQVINLLSSQAAISLENAQLYQQAQQALEDLKNAQLKIVQSEKMSALGNLVAGVAHEMNNPLGFISATLEQSKPALADIVEHLGLYQENLSEPGEEIIEHAEEIDLDYSLEDLPKMIDSMVMACDRLKNISTSLRTFSRADKDYKVKFNIHDGLDSTILILKHRLKANDKRPAIEVIADYGEISQIECFPGQLNQVFMNLLANAIDALDESNDGRSYEDIKANPNKIIIKTLTENEQIKILISDNGKGMSQEVKTQIFDHLFTTKGVGKGTGLGLAIAKQIVEEKHEGCLEVESELGKGTSFYIKLPIIS
>NC_019678|6504720:6556934|6514655_6515288_+|WP_015121143.1|DBSCAN-SWA
MTAYPPYPRLLKGSIVVLNSSGTIVSDIIPFQYNPESLSRTLQVQATSNEGGERMEALRLEGAPVETFKLDIEIDATDGLEKGQVSAVTLGIYPQLSALETLIYPTSGQVKKNMRLADKGSLEIVPMEAPMTLLVWGVQRLLPVRITDFSITEEAYDINLNPIRAKVSLGLRVLSYNDLPWKKRGSQLFMAHHKFKEGMARLNSITNLTS
>NC_019678|6504720:6556934|6549885_6552357_+|WP_015121161.1|DBSCAN-SWA
MNQNQPKFNYGEALQKSNLFYLVQRSGDLPDDYVISWRDDSAVNDGADVNRDLSGGYYDAGDHVKFGFPMAASMTMLGWGVIEYTEGYKKVGQFDNTLENIRWGTDYLLKAYDDKGTATTSDDVFWGQVGNGQIDHAYWGAPEDMTMPRPAFKVDAQNPGSDLTAESAAALASASIAFRSTDAAYADKLLEKAKGLYEFAEQYQGAYTDSITNTRSFYNSWSGYEDELAWGAVWLHKAIQANGETDSQYLDKAQNYYKGITPGWTHNWDEKSYGTAILLAQLTDKSQYKQDVEAWLDNWADPNGGIQKTAGGLAWLDQWGSLRYTANTAFLAGVYGDTVNDKQGKYTEFSESQINYILGDNPNNFSYMVGFGENYPQNPHHRAASGTTNIGDSDSNEYTLYGALVGGPSAPNDDAYQDKRTDYIANEVALDYNAAFTGALARMTEQFGGEALTEIPGINLDGSTNPNDSGGNDNPDVDNPNDSGGNDNPDVDNPNDSGGNDNPDVDNPNDSGGNDNPDVDNPNDSGGNDNPGGDNPNDSGGNDNPDGDTGTLKDVQFSVVNQWNNGFTGKIKITNNSNQAIDGWELEFNAPFEIKNTWDASIESDEGNEYVIKNLGYNRLIASGESVEFGFQGSYSGDINLAIDNVELNGTGNLSSAVGLTDSNPIVPATASDNPDESSNPIDPITGSGDNSNTDNNPTDPITSGGNPDSANEAIDNVVFSLVNQWNNGFTANVKITNNSNEVVNGWELELNTPFEIKEIWNGSIESQEGNEYLIQDVGWNASIAPGSSLEFGFNGINADAISEQDIINQISFSSDSLPISDS
>NC_019678|6504720:6556934|6508630_6509062_-|WP_015121141.1|DBSCAN-SWA
MKLIQYQANVLWDNLSSPNTAKIYQQALVKTWNLLKETAILLLMLLLLVVVFVLWVWHIGFTIGWKFRQWMESPNKEPEKLVENTIKSLVNSFAQVFNWVKNFAKKRLGLELPESEFKFLQGDSQTETNTNKQENSESKVKSK
>NC_019678|6504720:6556934|6504720_6505458_-|WP_015121136.1|plate|DBSCAN-SWA
MRPLSAQQILRIWEIGQSQHPLDRALTLLAFACPEISPPQLACLSIGQRDAYLLTLREITFGQKMNGLAECPNCGDRLEFDINIPDIRVAEILSPKVEKYNLQVEGVELQFRLPNSKDLAAIVGYKDVNKANSVLMQCCILQASQSGNSLDYDDLSATVINQLVQQMAECDPQAEILLNLSCPACQHSWQLLFDIVSFFWTELTARAKRLLQEVHTLARFYGWREADILSMSSIRRQMYLDLIGS
>NC_019678|6504720:6556934|6506126_6507692_-|WP_015121138.1|tail|DBSCAN-SWA
MPTAPTYPGVYIEEIPSGVRTIVGVATSITAFIGIASRGQTNKPVRIQSFADFDRQFGGLWVKSTMSYAVQQYFLNGGTDAIIIRVVASDATKATATVGGLELEANSQGDWMNGLKAVVNYETRPQRPNEAPLFNLKIQQVQDADGQPLNQPAVLEEFRNISADEDSPRFVTTVLEQESALVSVANNPSERPSVGDASFSGGANGSLPTYGDYTGEESDPDDPNSGPSTGIYALDAADIFNILCIPPITRDPGDSVDAVTTLFPAAQYCKKRRAMLIVDPPANWKTIGAAKDGVNDLRSALGNAFATNAAAYFPRLKMPDPLKENRIQEFVPCGIIAGIFARTDAQRGIWKAPAGIEASVSGVRQLAYKMTDLENGILNPLGLNCIRSFPVYGNVVWGARTLAGADQLASEWKYVPVRRLALFMEESLYRGTQWVVFEPNDEPLWAQIRLNIGAFMNNLFRQGAFQGSSPKEAYFVKCDKDTTTQNDIDRGIVNIIVGYAPLKPAEFVIIKFQQIAGNIAT
>NC_019678|6504720:6556934|6517825_6518149_+|WP_015121147.1|DBSCAN-SWA
MPGFLLNVGSVVFCAHGGQAKPTVPNPRVKVMGQPVTTFGPPYMVAGCANPPPPVNVGPCIVCNWITASLRVKVMGMPVLLQDSKSVCVPTGTPANVVFTQLRVKAM
>NC_019678|6504720:6556934|6554849_6555479_+|WP_015121164.1|DBSCAN-SWA
MQTTQRQHYKNLFTDSPTPRSGWVGIIDRFIGPGATPAELWLQFLPAVIAAIAAPAYALTLSDSWTGLQLGLIVLLGFDCVGGILTNATASAKRWYHRSGQGWQQHMIFVASHTIHISLVALLFRESDWAFLIVVSAYLLIASIGILRSPLYLQRPIALGFYGLALLGDRYLFSPTLGLEWFLPFLMLKLLVSHLLAEIPYSSDVDRQY
>NC_019678|6504720:6556934|6521514_6526461_+|WP_015121150.1|plate|DBSCAN-SWA
MTNSDSPKPIYNRPGLPAIVYRVGDYNSFRQRLISQLSSQIVQSDTPSTRRPLTRLTTRSNEDPAIALLDAWAVVADVLTFYQERIANEGYIRTATERFSVLQLARTIGYELSPGVAASTYLAFTVDDAIESVTQAIVPQGTPVMSIPTTDDEVPQTFETSAEILTHLDWNSIQPRLSKPQVIAENINQIYLEGTSTQLQPGDWVLLVGNQEQDIETYLLNLTAVELSADNNYTLISWEKQLPQAIKSRLRNPEIFAFRNSASLFGKNAPNWEDMPDEIKKAAGGTLAGGVFCSEDNGSNWISVNDNLANTDILCLAASSKNLFAGTPDRGIFRWQDGKNWEAVNAGLTNLNIQALYIQPGKGYIFVGTPGGGVFRSKDNGDNWVPIHTGNVQVQGKGDNNWQSVNTAIPNTVVRSLLTYSTTTNSGTGTIESEGNNVSGEGTEFTREFNVDDTITVGNESRRITEINSDVSLQVDSPFISNLASGTSFTTPNREINYIFAGTDSGVYRSQDAGKNWIPQGLLDGLSDRVIRALTNDESDIFAGTDNGIYRSSDYGKNWQSKRLEDADNVFSLINYQLGDKTYLFAGTDNGVYRSEDEGETWTTFNNDLPENITVYALDSDDTNLFAATNEGIFTSTNNGDSWQEINQGLTKTNITSLAVNHKIFAGALFSGFKETEWLDFEVTQPEIDLNTIYPKILENSWIVLLNENLFQAVRVNKVSTDSVSKFNLTSEVTQIAFNNSVDLSGFGRRNTQVLIQSESLALAPEVLTVRMQQENIFLDPINKDKIYLSKFIPDLQSDKTLIVSGKHIRAIAEDIGGFFVWNADENKWQRHNQGLTSTNIQALAVDETENEYQYYIGTSQGVFRYLDKNQTNNPIWEPLKNQGLSDTDIQALCIPQTKELFAGTPSGIFYYSDSGWEARNQGLVHKNVQTLVSYQEGETISIFAGTFDGGVFVSRNNGESWNSTGLTNADVQTLVVNTETGELFAGTFQKGIFHSDNQGNSWQQLTNIERGTGTISSDNITVKGAGLNSQQLQVGDIINAGGQTRTIVSINNETQIITVDTAFRPDLAERTAFTINTGLTNLNITSLLILPQEQETILFAGTGGSGVFRSQDNGKRWQQVNTNLQDLEIRTLVKNSSNEIFLGTASKGIFHSVDNGDSWQAINDNLTNTDIKAIAISSNDNKDNIIAGGNGILISQDGFYTVPLNKSDLLWVISPPVKEKYLKWLVRDINGFVGNIETITDKELFLQPATEEDGIVSEVCTIKKPPTEQQNPVIVLKKPLKYAYDPETVTIYANVVMATHGETVVEVMGNGDGTIPNQSFILKQPPLTYVPAPTASGAKSTLEVRVNDVLWEEVDTLYEKDTHLQGYIIRLTDDNTPVITFGDGENGARLPTGEENVSATYRSGIGLEGQVAPESLTQLKDKPLGILEVINPLSASGAAPPESRDEAREKAPSQVRTLDRIVSIQDFEDFSRAFAGIGKAQAVPLWNGQSQLVHITVAAADGSQVDTDSNLYQQLVAAIDNNRDPIQFVEVDSYELQLFNVEAKLQFNPRYQQELLIENVTASLKAKFTFSNRNFGQDVTAAEVIATIQQIEGIVAVDLDALYKLGSSKGLQQSLKADLARWDEENDIAKPAQLLLINPQDIKLTTI
>NC_019678|6504720:6556934|6518295_6518655_+|WP_015121148.1|DBSCAN-SWA
MQQINYPFLIDNRGRIASPDYNQHIRQMIEQVLFTFPGERVNRPDFGTGLQQLIFDPNGGELAAATQFLVQGALEQWLGDLIELEAVEVENQDSKLTVTIQYIVKRTQEQRLEEFSREI
>NC_019678|6504720:6556934|6505570_6506116_-|WP_015121137.1|tail|DBSCAN-SWA
MAQFSVNANRFDPYKNFKFRVKWDGKYVAGISKVGMLKRTTEVVEHRVGGDPSTVRTSPGQSKYEPITLERGVTHDLDFEKWANKVWSFNNAQAPADSRTQEVSLADFRKDIIIDVYNEAGQKVISYNVFGCWVSEYQALPELDASANAVAIQSITLQNDGWVRDESVVEPSEPSYEDPAA
>NC_019678|6504720:6556934|6517025_6517826_+|WP_015121146.1|DBSCAN-SWA
MKEFWGKYRGKVTGSKDPLHLGRVQIEVPAVLGEGRKSWAMPCTPYAGKDIGWFTVPPVGTNIWVEFEGGDPDYPIWSGCFWNENELPKNAQVDEPDKVQVFKTDGVTVTISNLGSNKGLTIEVDKPVVKRKLKMVFNADGIEINNKDETVVKLTADIIESNNQENSTITVTKDNIQLKENSVEIKLTSNSIDLIDNPSTIKLTTSGIELANNPAKVKIAPAAIELSDTPATTKVAPSGIEMSMGAASVKLSPVSVNVNNGALEVI
>NC_019678|6504720:6556934|6549091_6549517_-|WP_015121160.1|DBSCAN-SWA
MTSLTELMLILATVVGVVDGETIRAKNVSGQVATVKMACIHIPTRKSRRDEANQRLKQLLPNGNPIVIRFADTYKESQIVGEVFLNNKSINLQMVKEGKAVVDKTSVEQNCYESRIQYLVAEANAKQRGLGLWEKSRYVMK
>NC_019678|6504720:6556934|6515892_6517029_+|WP_015121145.1|DBSCAN-SWA
MAKGINLTLKIGSNNPQPASRELMEALDSVEVTHNDTGRSGFQIVFAVGRSGAKDQKDYKLLRNSLLKPFNRVILIVSFNAKPKILLDGIITNQQLAASNEPRGSTLTVTGEDVSVMMDLEEKSAEHPQQDEATISRMLISKYSKYGMVAKVVKPSLKERPTKNERVPVQQGTDLEYIKQLAERFAYVFYVEPGPVSTKNTAYWGPPRQGTKVQRALTVNMGSFTNVDSLNFQNNALAATTVAGKVQDRKNNRIQKVQDKSSDRPSLAQKSAVKSQTKVRVKQFRETGRSTAQAISRAQAMIDRSVDDVVTVTGELDSVRYGGLLEIRGKVGLRGAGYSYDGLYYVKSVTHKIRKGEYKQSFTITREGTGTTVRGVKV
>NC_019678|6504720:6556934|6555821_6556934_-|WP_015117034.1|transposase|DBSCAN-SWA
MPAKNHLSKEQRERLLKALKEYENPYVREKILILLLMNDGKTYQEISDFLNIAYGTVAYWAVHGDPDNLDSLLDGRREGNFRKATKEYEDLLLEIVDKEPSEYGYEFGRWTSARLATYLEKLTGIKLSGSQVRRILSRKKFVYLWAKYSLEDKQNPEKRKIFKEKLSEYLKITKETPERLQVWFWDESGFSLRVIRRKTWGKKGHRKKVTGQRRRGRVNIMGGLRYHDKKRMNFVIKKGDADVFYEQLTLLYSFILQEWVEKGNKIEYFNDYAAKIVIILDNASFHKRKDILEKIEKEMPNIILEFLPPYSPDYNLIELVWHSAKEYIAHRLFESVEQLEELLNKLLNQGGLIIKWDRKIKNKGNAVYSI
>NC_019678|6504720:6556934|6548503_6548998_+|WP_015121159.1|DBSCAN-SWA
MTKAVKIVRNLIIGFALITMISAIGVYGLIIFVFSAENVEEYESKQALSSLQIRFAKGNISNAYVATSTYWHDYNYYARFNAKADFIEKFIVETKNNRNKLQEEPIDSKACQIILSEKIRLSWWNPQEFDVDKCYSDKNISPGTFSVLLYHPESRTAFYYHHNN
>NC_019678|6504720:6556934|6545075_6545648_-|WP_015121157.1|DBSCAN-SWA
MKFIRLVCIALMGITIVNAKPTAAVPRKRNQKPIPSFTQLCKHKESLPKQTKYTVKVLLRKAGTNNCDRAQQKLRKKQILDLSSHKISDLSPLAQLTNLKELYLSYNQISDLSPLSRLTNLNFLFLESNQIGDLSPLSQLTNLTWLFVGENPIKNKTCPVKPESICEFEKNGDELLIPEDVDTIAQLPQL
>NC_019678|6504720:6556934|6554155_6554752_-|WP_015121163.1|DBSCAN-SWA
MTQEKRRLEVSQAAWQVIVREGLDRTSMRAIAQEMGCTTGVVTHYFRNKQELILFALNQVTEKLKTFMAEAIDSVSGIERLVTMLSAFLPLDRERQDILRVWVAFLGYAVGRENLMSEHQQSAAQLREMLVEELEGLQAANLLRQDIKPGIEANALLALVNGVSLDWLIQANRLTSEEQRLVIERYVKEMLVENPVSN
>NC_019678|6504720:6556934|6518840_6521348_+|WP_015121149.1|plate|DBSCAN-SWA
MSTQYLCKNQLRRAKVLSKNILNGIDYLEVGADRKTLLVYFLHNLPGVAQEDSVPANSNALTADNILITGGIRVRSIVVESVTSFENLLTVRVSGNSDFSTYTLKLVDSDGITAPKGFDSQLSQVDFSFWVEDRSEFDCKTPDAPTEKQPPPPFIDYLAKDYASFRRLMLDRLAVTVPDWQERNPSDIGILLVEILAYGADHLSYYQDAVATEAYLGTARKRVSVRRHARMLDYFMHDGCNARAWVVLEVESKSQADGCILQAAVNSLKLQENKIKTRFLTKINLAKIQGEKDDIGVRIKPEKYEELLNQQPQVFEPLHDITLYAELNKINFYTWDNEQCRLPKGATKATLDFCDKPQLCKQLEGRVLIFEEVKNPQNGDCFDFDLTHRHAVRLTKVTETTDALNDDRKLLLVEWAVEDALPFDLWISNLDSKGAQIENISIVRGNVVLVDRGQTVEGDDADLGTVPQQGKYRPLLQFGPLTQQGYVRDNRDLWVTFNPEASATSAMNWEMRDVKPSISIWELGKRQIPWFSQQDLLNSDRFSREFVVETEDDGRTYLRFGDNQLGKRPTPGTSFQAIYRIGNGKLGNVGADTISHVVTDIDGITKVYNPLPAQGGTEPEAIEKARLDAPQAFRTQQRAVTASDYANVAQLYKGVKKAIANRRWTGSWYTIFITVDREQGLPVNEDETFKDNLRNFLESFRLAAHDLEIEGPRYIPLDIAMTVHLLPDYFRSSVKTALLETFSTSVLSNGKLGFFHPDNFTFGQPVYLSQVVTTAMQIPGVSSVELTKFQRWQQPSNRELENGQIPFDRLEIARVDNNPNAPENGQIVFNMKGGR
>NC_019678|6504720:6556934|6546288_6548289_-|WP_015121158.1|DBSCAN-SWA
MGEHKPATEERFLICGLGGLGQQCVIALKQFGVKVVGIELVEPKSWRIPGVDKLLDELIIGDCRQNSTFERAKIELCRAVLIVTSDELINAETAIAVRQLNKNARLVVRSTKENLNQLLEEQLSNYVGYDPIHLSAASFALAALGGDSLGFFNLNNNWLGVFQHKVRDRDIFHRRQLFEINSGSRKLLCYLPNKYDAFNCFYDWDSETVIKEDSTLIYVEQFDRLLSKQKKGAINNTPKKKQIWKEPANIFNQIKIRKKFLDYWHSGSQIRRLVIVSILVTIGLVTVGTILFYVLVGNSTSVNPLYLTISLLLGGYADFLYSVQPNSIILQFLALALAVAGTAFVGVLYALATEKLLSTKFLFSKKRSPVPEEEHIVIIGIKRVGSKAAKILQQFNQPLVAIALEDDFDDNHLPDIPLFKGDLNQSLTKVNLSTAKSVIATSEDEMLNVEMGLKALKINPKSNLVIRTFGQRLSENLAQILPKAQIISAYAVAAEAFAGAAFGENILDLFRLHNQTVLVTEYQFTEVDTLNGLMLSEIAYGYGVVPILYQKPPLQGELMPKAYKQIEPGISLTVLATIDGLKRMEAGRIGIYPKNWQVVIQSANTEEAKFEGANQIAKISNYPLDKARELINNLPQTLKVPLYKLQAQHLIRVLQKHQVMGILKRI
>NC_019678|6504720:6556934|6526688_6530852_+|WP_015121151.1|DBSCAN-SWA
MNQHSSVERLYNLLPAIYRIRDEAQGQPLRALLAIAAREMQVLEDDIDNLYENWFIETCDEWVVPYIGDLLDAQELYAQNSINYGQQQRRAYVANTIAYRRRKGTAPVLEQLTRDVTDWRARAVEFFQRLATTQNLNHLRPNNTTVNLNQSGQPEFLGTPFEQQVSYSINIGDALEGRGFHNIPNIGLYIWRLQSYPMEKATARMVEGGEVDGRYYFSCLGLEDFPLFNQPQTETDILHLAEEINVPAKLRIPPLKKEIENLLNKKESSNNIGYFDATPVLEVFVDGEESSIPPKEILIAPLKVEDNNDWMSVKWNDFDSNIRVAIDPESGRLAFPPSQLPSEVEVSYFYGFSGDIGGGSYQRNLSQESCVWEREIYQESLGRVIQNWNASVEVWKCLQQGNGVALGEIFVGDSVSLQDYGLNNRREAEGRDDEKLQVIVSDDGVITVKAGMVRDENDNPICLENDCQLDVSAFAGESLILFITHQPGLGLPDLRVVNHGAGDGWLCLGVALKEVFEKTESVISIPDNKTYFGDLTIVIPADKTLKFMAADGFRPHLLGNLYVQGITPFGNNTKNINNPGEFILEGLLIEGKLTVLPGSLRSLHINHCTLVPKEGGLRVATWEVVEDDDNNEISDDSWTLIAIAIYFINAIRSLIGKGTPGKSFNILLKIAIKQAQLVFSQFRELIQWRCVDEYPVADGCLQPGMKDSLNYQLDNSRLTISIYRSICGALHLAETVPTLLIEESIIDNNLGADTTADIEKLVAIDASGTAVEQLQSSTVFGTTKVRSLEASDSIFTGRVTTLRKQIGCMRFCYLPDGSQTPRRYLCQPDKALAEEFDISKLPSAITCLTINKIDSSHHQLISGTSGKGLFSYQINQDNQNQWQPINKGLDNFNITTLFYQEQEIYAGTIGGDVFRSQDNGNSWESINHKEEIEPKKATGTISSAGRIVKGNKTNFIQELKIGDIITANGQKRIVTQIDSNYFFCVNTPFEPSLDNVGFSISNLILNTDITAFAVHESTIFAATARGGVFGFLKEPDKPEEPEKWTAVNVGITNLNVTSLIAGEDGYIYAGTYGGIFRTRDPGEGWLAISFGLENLEITALTIDVTRQLFAGTSGGGVFRFDEYSNIWTAVNDGLSNSYITVMAASGQRCDGTVSSEGNKLNGENTNFTADFLGRSITATGQTRTVTKVVSTTEIIVDESFCPELPAETIYSYEKFLVVGTVGGSIFYSVNSGETWQQVNAGLSDTDVSDLVIIPSVEEAGSREQGAGGEERNNSDRAIFVGTTAGNILCLSDDMQTWKSLNSGLVNVEDKLRVLSKIQPRFTSKQYGNPAYAQLSQNCAVEIRTGAEDGSEMGVFSYLKQPQRQANLEASLKEYLRFGLKVGIFYET
>NC_019678|6504720:6556934|6515434_6515725_+|WP_044292323.1|DBSCAN-SWA
MFEPTSRYYNLETAQITTTDGRRIAYKRRRFLPQGRDMPIAEEVIVKDEDRLDLITFATLGDSEQFWQICDANNAMNPPELIAEPGRMLRVPIPEV
>NC_019678|6504720:6556934|6544117_6544852_+|WP_015121156.1|DBSCAN-SWA
MTLDFWVKTNGTWINAISVILGTAGGMLLKHRLPLRMQRIITQGVALITLFIGFHMAQSLLQVKNSRVDGVVLGLVAIIIGGLLGEWWHLEERLYRVGEFLKVRFQKSGYFTEGFVAGSLLFCVGPMALIGSLNNGLTGNNTLLILKATMDGITSIALGSSFGIGVGFSSLVILVYQGGVSLLAGFLIQSLPDPTHDPHLLLITGVGGLTVIGLGFNLLEVSQVRVASFLPALLVAPLLYFLCQ
>NC_019678|6504720:6556934|6543365_6544061_+|WP_015121155.1|DBSCAN-SWA
MLTLQSIENVEDVISSIENFEDTLSSIEDVENALQLKFHKQVTEPGIKNPVKFLQRWSYLSTQVTRLAGAALSRAHLADIQYLLAEIAYSECGLGNKDETHSKLMIELINKSPHADAITQRLDTYFLNLFEETILELSQMSQEEAVGFIVSLEAPAYQILELLKQTSIAVGIFEVDFLNSEYFLIHDAMEKEHQKSCNESMQVVVDNGLELSKIYKGGERGIKFLVEFLGC
>NC_019678|6504720:6556934|6552775_6553534_-|WP_015121162.1|DBSCAN-SWA
MEFNPSNQLEELLVKAANDPVVRNDFYKLILESDIFLVQPPNSKPSYGSRIAGEQESISIQSMEINGNVYLPFFSSFTALQRAIREESDYVSFNARTFFEMTKGQKLLLNPNNDCGKEFTVEEIASLLDGSIFNQDSAREVQSGTEIMIGQPANYPKALVEVLKNYLTKFKSVKSAYLAHFFDPSYDEKPHTLIAIEDYGDWDAVISGLDLCIRNIEIPDPPVDFVKIDSSESYFSDYFKNNCEPFYRRGTD

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015121136.1|6504720_6505458_-|plate	T4 bacteriophage base plate protein	NA	NA	NA	NA
WP_015121137.1|6505570_6506116_-|tail	phage tail protein	A0A1J0GW41	Streptomyces_phage	1.0e-09	30.9
WP_015121138.1|6506126_6507692_-|tail	phage tail sheath family protein	J9PVC2	Bacillus_phage	1.5e-56	30.5
WP_015121139.1|6507758_6508169_-	hypothetical protein	NA	NA	NA	NA
WP_015121141.1|6508630_6509062_-	hypothetical protein	NA	NA	NA	NA
WP_015121143.1|6514655_6515288_+	hypothetical protein	NA	NA	NA	NA
WP_044292323.1|6515434_6515725_+	hypothetical protein	NA	NA	NA	NA
WP_015121145.1|6515892_6517029_+	phage protein D	NA	NA	NA	NA
WP_015121146.1|6517025_6517826_+	hypothetical protein	NA	NA	NA	NA
WP_015121147.1|6517825_6518149_+	hypothetical protein	NA	NA	NA	NA
WP_015121148.1|6518295_6518655_+	GPW/gp25 family protein	NA	NA	NA	NA
WP_015121149.1|6518840_6521348_+|plate	putative baseplate assembly protein	M4QRQ3	Synechococcus_phage	1.1e-08	29.4
WP_015121150.1|6521514_6526461_+|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_015121151.1|6526688_6530852_+	hypothetical protein	NA	NA	NA	NA
WP_015121152.1|6530863_6534829_+	hypothetical protein	NA	NA	NA	NA
WP_015121153.1|6535684_6541117_+	AAA family ATPase	A0A1B1UZQ2	Malacosoma_sp._alphabaculovirus	1.2e-07	34.9
WP_015121154.1|6541272_6542880_+	SidA/IucD/PvdA family monooxygenase	NA	NA	NA	NA
WP_015121155.1|6543365_6544061_+	hypothetical protein	NA	NA	NA	NA
WP_015121156.1|6544117_6544852_+	DUF554 domain-containing protein	NA	NA	NA	NA
WP_015121157.1|6545075_6545648_-	Leucine Rich Repeat (LRR)-containing protein	NA	NA	NA	NA
WP_015121158.1|6546288_6548289_-	Kef-type K+ transport system NAD-binding protein	NA	NA	NA	NA
WP_015121159.1|6548503_6548998_+	hypothetical protein	NA	NA	NA	NA
WP_015121160.1|6549091_6549517_-	thermonuclease family protein	NA	NA	NA	NA
WP_015121161.1|6549885_6552357_+	cellobiohydrolase A (1,4-beta-cellobiosidase A)	NA	NA	NA	NA
WP_015121162.1|6552775_6553534_-	SseB protein	NA	NA	NA	NA
WP_015121163.1|6554155_6554752_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_015121164.1|6554849_6555479_+	hypothetical protein	NA	NA	NA	NA
WP_015117034.1|6555821_6556934_-|transposase	IS630 family transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_5

Nucleotide sequences of DBSCAN-SWA_5

>NC_019678|7907518:7956560|DBSCAN-SWA
TTTATTTACTAGTTTGGTTCTCAATATACTTACGAATAACGTCGGTACTTACTTGTCCTGTAGTAGCTACAAAGTAACTAGGACTCCACAAAGTAGGTAATTTTTTTAACTGTGGATATTCCTTCCTTAGAATATTAGATGCTCTACCCTTAACCCACTTTGCAATTTGAGAAGCTGACTCATGTGGCGGTGAGTTGATAAACATATGTACATGATCTGGCATCACTTCAAGAGCGATTAATCTCCAGCCATGTTCTTTTACTAACTCAAAAATAATTTCCTGTAGCCGCATAGCGATTTCATTAACTAATACTGCTTTACGTCTTTTTGGGACAAACACAAAGTGATAATTTATCGATGACACGGATTTTTCAGCCCTTCTGTATTCATAATCTGACGCTGACAACTTAGCCATTTTATATCAGGGTTTTTTGTTGATTATTTATGTTGAATCAACTATATTAATAAACAAGGAGGTGGTCAAGTGTACAAAACAGTTCCAATAAAAGCAAAATTTACGGATGAAGAAAAAGCTTTCTGGGTAGATCAGTGTGAGCATTCAAACAGTTTATATAACTCTGCTATTTATCTGGCACGCCAGAATCATTATGCAATGCTACTTGAAAGAAAGGCTAATACAACTTACTGGTGTGGAGATGAACTTAGAAGTGGTTGGAAAACTTACAGATTAGAAACTAATTATTATCATTTAGATAAACAGCTTAAAACTTGCATTCACTACTTTTCATTGGCTGCACAAGCTGCACAACAAACATTAAAGTTAGTAGGAGAATCAATAACTAGTTACAATAAATTAGTGGATAAGTATTACTTAGGAGATGGCAGTAGGCCATCAATTCCCAAGTACAGAAAGTCTGGTGGTTTATTCGCAGTTACGTTCCCAAAACAAGCCTTGGCTTGTCATAATGGTTATATTTATCCCTCAATCAGTAAAGCAACAAAGCCTGAATTAATAACATCAATTAAGCTTATTTTGCCCGAATTTATTAGCTTTGATTGGATTAAAGAAGTAATTATTCGTCCTAGTCGTGGAGAGTTTTGGGTTGATTGGGTGATAGACGATGGTAAACAGCCAATTATAAATAATAAGAGTCTTAACTACAATCATGCAATTAGCATTGATCACGGTGTAAAGTTTTGGTTGTCAGCAGTTACTACCCTTGGTAAAAGTTTTATTGTTGAATCTCCACAGCTAAAAACTGCACTCCATAAATATCGAAATCAAGTACAGCAACATAAGAAAAACAAACCTAGTAGATACTGGGACAATTACCTTGATAGAATCACAGCAAAACGCAATTTACAAGTCAGAGATGCAGTAAATAAAGCCGCTAGGTTTATCATCAATAAATGCTTAAAAGACGGTATCGGGAATTTAGTAATTGGTTGGAATGAGGGAAATAAAACCAACATTAATATTGGTAGAAACAATAATTATGAAGTTGTTTCAATGCCAACCAAAAGACTTATTGAGAGGTTAAGACAATTGTGTGAAGAATATGGTATTAGATTCCACATAACCACTGAGGAGTATACTTCTAAAGCTTCTTTTATTGATAATGATGAATTACATCAATACGGTGCAAAACCCATAGAATGGAAGCCATCAGGTAAAAGAATTAGTAGAGATGTATACCGCACAAAAGACGGTTTATTGATTCATGCAGATTTAAATGCAGCATCTAACATTCTACGAAAGGTTGCCGACCAGATTTTTATTAACTCCGGCATCGCAAAACTAGCTTTTGAAATAATTAAACGGGGTGCTTTGACACACCCCAAACGGTACGATATTTTTAGTAATCTAAAAAGGTCTTATCGCAAGCAAACAATGTCACGCAGTATGTCTTTAGACTACGGAGTGACAACTGCTTAGAATCCCAGTTTTTTTCAAAGCTGGGAGATGTCAAAGATGTTCAACTTTACCCTTTCCCCTCTCCTTCACAAGGAGAGGGGTGCCCGGAGGGCGGGGTGAGGTAATAATGTATTCTACTCAACTGAAATTCGCTATAAATGATTAATACAAAATCTAAAAAACCCTATTTATTCGTTTTAAGATGACTTTAACTTTCGCTTAAAAGTGGTGCGTGGTGCGTTACGCTCCGCGATAACACACCCTACTTTTAAATCAAAAAATTTAAATCGCCAATCACCCATTACCAATGCCCCATGCCCAATGCCCCATGCCCAATTATTTTTACCACGGACTTCCAATTAAGGTAAAAGATGACCAATAATAGGGATGTGTGAATTTTCTGCTTCTCCCGGCTAAGGATGGAATGGGAATAATATTTTTTGATTGCGGTAGCTGTAATATTCCTTTTTCTAATGACATTTGCCCTTTAATCATGGCTATTTGGGTTTGTCTTAAGGCTTCGGCTTTGATTGGTGCTTGTTTCAACTGCTGGTAAAACTGCGTCATTAATCCTAAAGTGCCTTCGTCGCTGACATACCACAGGCTACCTAATGCTGATTTTACGCCAGCTTGAACGGCTAATCCGGCAAAACCTAGTTCTGCTTCTTTGTCTCCTAATGCTGTTCGACAAGCACTTAAAGTTAATAATTCTACTGGGGGATTATTCCATCCTAGTTTTCTGATTTCATCTAACCGCAATTTTTGGTTTGATAGTTGAATGTAGGAATTTTTCAGTTTTCCAGGGCGAAATTCTGCGTGGGTTGCGAGATGAATTATCCCAAAAGGCTGGTTTGAACGTTGGGATTTGAGGTTTTCTAAAGTAAAACTGTTGTTAAGGAAGGCTCTGCCTTTCCACTGTTTGGAAATAGTATTAATTTCTAAAGGTACGGCAGGTAGAGGATTTTGTTCGGTAAATTCTGAAGCTCCCATTGCTAAAACTTCGGCTTGTTTAATGTCAGCGTAGTTTGTATTGGCAAGGCTGAGACTGGGCATCAAACCCATGCTATATTTTTCTATTAGAAAACTATTACCATCATTTAATGCTGCTAGCGGTATCGAACGCAATCCTACATCTACAATAAAGCTTAAATTCTGAATTCCTTGAGTTTGCAATTCTGCTTCTATGGGAGCTATCACCCACTGGTAAAGTTGTTTTGATGGTTTTAAATAAGTTTTTGTGGTACTTTTTCGCGGATTGGAAACTTCACGCTGGAATTTTCGCGCTACTTTTAATAGGTTGCCACGGGTTGCGCTGCGTATCTGTTTGCGAATCGGTTTACCTTTGCCGGTAACGAGAAGTATTTCTAAAACATCACTATCTTTTTTGAAATTAGTTTTTGTATTTTTCAGTTTTGAGTCAAGCTCTAAATCAGAAGCAAGACTTGCCGGTACAAACATCGCATATACTAAAGCTGGTTTAATGCCAGTAGCTTTTTCAACAGAATTTAGGATATTTCTTGCTTCTACTAATCCTTTTAATGTTGGATCGATTTCTTTTCCCAAATAGTTTTTAAATGCATTGGTAAAGGAATCTTCCACTTTACCCATCATTCTATCAATTTCGAGGCGACTGCTTTGATTGAATGTTCTATCTATTTTTAATAAAGGTGGTTCTCTAAATTCTGGCGGTTTGGGTAATTTCTGCCGATAGTTTTCGGTTTCGGGGTTAATTTCGGGTTGTTGTTCGGAAATATTGACGCGAATTTCAGTAGGTGTGGAAACTGAAATTTTATCGCTAGCAACGATTGTAAAAGCATTTATGTTTCCCGTGTTGTTAGCATTGGGAATATATTCTAAACTATCTTCAGAAGTAATAATATCTCCAGCAGTAGCTTCGTTACCATTAATTTTTAATGTTCCTTGTGGTGCAATATCATTAATTTTCAACTCGGTAATATCGTTATTTACATCAATAACTTGAGTGCCAATATCTGCTAGTTTAAAAGTAACAGGTTGATTTTCTGCGGTAATATTTAGAGCAGAATTTACCGTTACATCGGGAGGAGTGTTGGTAAAAGTAATGTTGATATTTCCTTGATTTTCTGTACCGGGGTTAGGAAATTCAGTAGTAGGTGAAATGATATTAGTACCAGTATTAATTGCACCAGCGGTACCGTTAAGGCTGGCATCTCCGACAATAAACGGAACATTTTCTCTAGTGCCATCGTGACGAATTTCTACAGAGCCAGATGAATCTTCTCCAACTGTAGCTATAGTGTTAGGAAAATTTAATTCTATTAATTTTAGTTCTCCTTCTCCTATATCAATCTCTTCTGGAAGTTTGAACCATTCTGGTATTTCTAATGCTCGGACAAAATTTTCTTCTTCTTCAATTCGATCTTCAGCGGACACATACAGCCCTCCCCTAACAGTACCATTATCGGCAATAATTTTGACATCTCCACCTCTACCCACGGGAGAATCTTCTTCTTCAAAATTGCTACTATTAACGCTTCCAAAAAGAATATTTTGACCGGAATTAATATTTATATTACCAGCAGCAGCATTCTGAGCAGAAACACCATTTAGCTCAACAAAAGCCTCAACATCTGCAACATAAATATTACCATCTGCTGTTAAATTAATATTCCCCGCTATTCCATTATCAGATGTCGCAGATAAAACCACTCCCGAATTAATTGAACCATTAACAATATCGCCGATTGCTTTTAAATTAACTTCTCCTCCAAAAGCATTATTAGGTGATGTAATAAAACCATTTACATCCACAGAAGATTTAATTTCGCTGACAAAAATATCGCCACCGGAATCAACATTAATTTTTCCTGCTGAAATATCATTTGCACTTCCTACAAATACTTTTGCATTAATACCATCTTCTATAACAACATTGCCTTCAGCTTTTATATTGATGTCTCCAGCAGAAATTTGGTCAACATTTTCAAATGTAGTTGCTTCCGAACTAATACCTTCTCGTACAACAATATTCCCACCAGCTTCGAGATTAATATTTCCTCCACCAACAAAATCCCCAGCGTTTATATCGACACTAGAATCAATCTCGGTTGCAGAAATATTACCTCCCGCATTCAGGTTTACTTCACCCCCAAATGCATCATTGACAAAAAATTCTTCCGAACTGTATTCAGTAAATATATTACCCGTAGTAATATTTCCTGGTGCGCTGATAATTACTCTACCAACTCTTCCAACACTTTCATCAAAACTGGTGATAATATCCCCATTAACTGTTACATTTGCTGGTGATGTAGCTGTACCTTGAACAGTAAAAGGTACATCATTAAAACCAGAGGGATAATTAAAAGTAGGCTCTTCAAGCTCGGCTACTCCAGCCCTTAAAATTAATGCAGCTTCACTCGCTAAAATTTGAGCATCAGCAGAACAAGTTGATTGACATATATCAGAATCTAGGCTGGTAATTTCAATATCACCTTCTACTGTAATGCTACCTTTCGACTCAACTTTTAAAGCTGCTCCGACATAGCTACCAAAAGTAACATCTTCCTCAGAACTAATAATTGGGTCGTAAAGACTGATAAACTTACCACCATCACCCTGTAAATTCAGAATTGAAAATTTACCGCCACTAGCAAAGTGAGCATCGCCGGAAATTATGCCATTGCTAACTAAACTTAAATCACCACCGCTGACAAAAGGTGTTTTATCCAAGTGATTCAAGGCTAAAATATCAATTTGGCGATCGCCTCTCAGATAAAAGTCTCCACCAGCAATTGCAATAAAGGGATTCGTCGCACTATCCCTTACTCTTACCGTATCTTTAGCTAATAAAGTCAGGTTTTCTGTAGTTTGCAACTGACTCTCGAAAAAAGTTAGATTGCCATCTGCTGATAGCAAAGCATTTTCAGCATTTAAAGTTTTAACAGTCGCATCACCTTGATTCAGCGTCAAACCCGAACCTTTTAATTCAACTTCCCCGTTACTGTTGCGAACTAATTTTGTAACGCCGCTATTTCCCCCGGTAAGCATTTCCGGTAAGGAAGCAATCGTTAAATTCCCCGGTTGAGGAAGATTTTTAGCAGTAGAAATCGGTTCAATTTCCAAACTTAACAAATTCCCCGGTTGACTCAACCTCAGCAAATTTTTTCCGGGAACAGCGGATACAATTATATTCCCCGATGCTGCTTCTAAATTTCCCGTACTCGCAACGCTGCCACCAAGCAAGCTTAAATTACCATTGTTTACATTAAGATTTCCAGCATTGATAATTGCTCCCGGCTGACTCATGGTAAAAGCAAAACTAATCGGTTTACCCGTCAGAATTGCATAATCGTTTTTACCAAAAGCATTTAACCAATTATTCCCGAATCCAATACCATTAGCAGTTGTCGCAGTAAAATCACCCGGTACATTTAAACTTGCATCGTTGCCAAATACAATTCCCGATGGATTCATCAAAAACAAATTTGAATTACCGCCGCTCACCTGTATCAAACCATTGATAACAGAAGGATTACCGCCAATTACCCGCCCAAAAATATTTTGAATTCCAGGATTGCTGAGAAAATTCGCAATCTGATTTTGACTTAATCCCAACTCTTGAAAACTATGAAACAGATTGCTACCATCTTGAGAAAATTGCCCGCCAGTAATATCGAATCGATTACCATTATTATTAACTACAGTTCCCGTTTCATCTCTTGCGGGAATTACTGACTGCGCTTGTGCTTCGAGAATATTTACAAATAATACCGAGCTAAAAATTATCGGTAATATTGAGTTTAGAGTAGAGAAAATACTTATATGACGCATTGATTTCTACACCAGAATAATAATTAATTTAAATAAAAATATGATTTACTGTTAATTAATAGCTAATAACTTTACTTATATTGTCATATTAAATATTGAATGGCATCATCAAAACTTAAAAAAAATATCTAGTTCAGTATTAATATTTAGATATTGGGTTACCCTTCACTTAACTCGACCTATCTATCTTGTTAAATACTTACACGCAGTTCGGCAAAAAAAATCATAAATAGCCTCAAGACTTAGTTAATAGTCATGTTATAACGATAGTTTTACAATTAAGGTCAATATTGACTATCTCACTATTTAATAGTACGTAATTACACTTAAAATAAACCTGAAAATCTGAATTATTATTTATTTTCGATTTGCTTTCCTAGTTTTTACCGAATACATTTTCCCCTCTCTCAAAACAAGGAGAGGGGTGCCGGTTGGGCGGGGTGAGGTTTCCTAATCCTATCTCGCTTTAACATTACCTGTCTCTATAAAAGGGAGCATCCCAATGCAGGAATAAATACTTTATCCGACACCCGCTTATGGGTGCGGCTACAAAAACAAAGCCCCTTCGGGTTCGCTAGTTTGGGGGACGGAAACCGACACCCCCAACTAGACTCACCACCTGCGTGGGCTATGAGAGTTTCTAAGCCCACGCAGGTGGGCTTCGTAGTATTAGCCCCAGGCTTATAGCCTGCGGGCTTTTTGCCGCCATTGGGATGCTCCCCTATAAAAGCTATTTTCTCTGCGCTCTCTGCGGTTTTTTATAGGAAAACTTCTACCGGGAGGGGAGTAGTCTATTAAAATCAAATCTTTGAAAAAGGAATATTGTAGCTATGTGGAAAATATTAAAAAACAAAGTTTGGCAGTGGAGTAGTGTATTAATCGCCGCTCCTAGCGTGACTTTACTTGTAATGTTGGTGCGTTTGAGTGGACTTTTGCAAATGTTGGAATTAGCAGCATACGACCAACTTTTTATATTGCGAAACTCAGAAAAACAAGATGAGCGTATTGTCATCGTAGAAATTGACGAAGAAGCGATAAGAAAATTAGAATACCCGATTCCCGATCGTAAGCTAGCTCAAATTTTGCAAAAAATAAAACAACATCAACCCCGTGCGATTGGACTCGATTTTTACCGAGATAAGCCAGTTGGTAAAGGTTATGATTCGTTAGCTAAGGTATTTGAATCTACACCCAATTTGGTAGGAGTACAAAAAGTAGCTGGAAGTATTGATAGTGCGACAGTTAATCCACCACCAATATTAAAAGAATTAGATAGAGTCGGAGCAAATGATTTTCCTTTGGATGCAGATGGTAAAATCCGTCGCGGCTTTTTTTACTTAGCAGATAAAGATGGCAATCAAATATTTAGCTTTTCATTTAAACTTGCTTATCTTTATTTGAATGCTATGAATATTTACGTTGGATTAGCTCCCCCGGATAATCAATTAATCCAAGTTGGTAAAGTTGTATTTACACCTTTTGGAAGCAATGATGGTGGTTATGTTCGCACTCCAGATGGTGATTATCAGGTTTTATTAAACTATCGCGGTGATATCGAAAAATTTCAGAGCGTATCTGTAATAGATGTTTTAGAAAATCGGGTTCCCAAAGACTTGATGAAAAATCGGATTGTACTTATCGGTGCGACTGCATCAAGTTTAAAAGATTTATTTTATACGCCCTACAGCGCAAATTTGTTTAGGAATATTCGCCGAATGGCAGGAGTTACGGTTCATGCTAACGCTATTAGTCAAATATTAGATGCCGAATTGAGCGATCGCCCTTTAATAAAAACCTGGAACGAGGAGTTTGAATGGTTATGGACTTTTAGCTGGTCTTTAGTTGGAGCTATTTTAATATGGCTGTTGCGTTCGAGCAAGCGCAAGATATTACCTCTTGTAAGTCTTGTATTGGCAGGTTTTTGTCTGCTTAGCATTAGCTATCTGACTTTCCTTTACGGTTGGTGGATTCCCGTTATTCCGCCGATGCTAGGATTATTCGGTTCTGCGGTTGGTGTTACTGCTTTTCTGGCTCAAAGCGCTAGTAAAATTCGTAAAACTTTTGGGCGCTATTTGAATGATGAAGTTGTTGCCAACTTGCTCGAAAGTCCTGAAGGTTTAAAATTAGGAGGGCAGCGTCGTAATATTACAATTTTTACTTCTGACTTACGTGGATTTACAGCTACTTCGGAAAGATTACCAGCCGAAGAAGTAATCAAAATTATCAATCTCTATTTGGGATATATGGCGGATGTAATTACCGAATACCAAGGGACAATTGATGAATTTATGGGAGATGGTATTTTAGTGCTTTTTGGGGCACCTACAGCCAGGGAAGATGATGCCACCAGAGCAATTGCTTGTGCTGTGGCGATGCAGCAAGCAATGGAACCAGTCAATCAAAAAATAAAAGAAATGGGATTGCCTAAATTGGAAATGGGCATCGGTATAAATACCGGGGAAGTTGTAGTGGGAAATATTGGTTCGGAGAAACGTACTAAGTATGGAATTGTTGGCAAGCAGGTTAATTTAACTTATCGGATTGAATCTTATACCGTCGGCGGACAAATCTTTATTTCTGAATCTACTTTAAAACAAGTCGAGCCGATTGTAAAAATTATCGGAGAGCGACAAGTTAAGCCAAAAGGAGTCCAGCAACCGATAACCATTTATGAAGTTGGCGGCATTGCTGGGGATTACAATCTTTATTTGAAGCAAGAAGAGGAACTATTTGTAAAATTATCGCAACCAATAATGTTTGAATATGCAGTGTTAGATGGTAAAGATATTAGCGATACTCTTCAAATCGCAAAACTAATTCAACTTTCCGAAAATGCCGCAGAAGTATGCATTAAGGTAAATTCAGATGAAGTAATTTCGATTCCCCAGCCGTTAACCAATATGAAAATGAATTTATTGGTATCTATAAATGGTGCAGAAAAAAGTGGAGATATTTACGCCAAAGTCTTAGAAAAACCAGCAGCATCAAAAAATAGTTTTTACATTCGTTTTACTAATAAGCCACCTGAAGTTGAAGCATATCTTGATTCAATCTATAAGTCGATGAAAAAGGATAAATAGATAATTGGGAATTGGGCATTGGGAATTGGGCATTGGGCATTGGGTATTGGGAATTGGGCATTGGGCATGGGGCATTGGGCATGGGAAATGTAATTTGATATATAGTGGTTTGTCGTTGGGTGCAATATACGAAACTACTTCCTTCCCCCTCTCCTTAATAAGGAGAGGGGTGCCCGTTAGGGCGGGGTGAGGTTCAATCTCTGTGGGTTTGATTCCACAAGTCTCATTGTTTTTACTTCAACAGGAACGTCAGAACCAACCACCACAAAGATTTTAGTTTTCAGATGTGTTTCGTCGGTTATCGAGACTTTTGGGTCAAAAACGCCATTCAATTACCTCTCCCTCACTCCTTCACTCTCTCACTCCCTCACTCTTTATATGCGACTCGATCCTTCTGGAGTCAGATGTAATTCTGGTTCTCCATGACCTTCTGTAGGTTCTTTGAGGAAAAAGGCACAAAGACTAGCCACAATCAGAGCTACTACTCCTAACATTTGGAAAAAGAATTGATCTCCTCCTCCACCCTCTGGAAGCAAACTATAGATAGTCAGATATGCCACTGCTCCGACATTTCCGTAAGCCCCTACATAACCTGCTATTTGACCAGTAACGCGATGTTTTACTAAAGGGACAATAGCGTAAGTCGCACCTTCAGTCGCCATTACAAAGAAAGAGGCACACATCGTCATAATCACGATTAAAGGGAGAGCTATTTTACCCAAACTGCTAAAGATTAAATAACCAATTCCCGTACCAGCTAGGGTTATAGCTAGCGTCCATTTACGGCTACCAATTTTGTCAGACAGCAAACCGCCTCCTGGACGAGCAAGCAGGTTCATAAAGGCATAGGTTCCCGCAATTGCCCCCGCCAATGCTGTAGCTAAACCAAAAGTTGTCTCAAAGAAAGTTGGCAGCATCGAAACTACTGCTAATTCCGAACCGAAACTAGCGATGTAAGCCAGTTCTAACAGAGCAACTTGAGAAAACTGATAGCGGTCTGCTGCTGGGTACTTTTTCGCACCTGTCATTAAAGCTTTATTAGCTTTAAAGATATTGAATGTCTGAAACAAATATAGAGCTACCAAAGCAGCAAAAATCAGATACATCGTACCTGTTCCGAACAGCCCTACTTTTTGCAAACGCCAAGCAATTACACCTAAAATTCCTACTAAAGGAACGTTCATCGCCAGCAAAAACCAGAAGTCTTTTTTACTAGTTACCTCTAATCCGGCACTGCTTTCAGGTCGCTGGTACACCTTGCCTGGAGGTGTATCTTGAACATTGAAGAAATAGAATGCTCCATATAGTGCAGCCAAAATTCCTGTAGAAGCGATCGCCAGTCTCCAGTTAAGTTGGCTCGCAGTTAAACCAGCTGTTATCGTAGCAATAGTCGGCAGAGTAAATGCTGATGCAGCCGAGCCAAAGTTACCCCAGCCACCATATATCCCCTCGGCTAATCCGATTTCTTCAGAATTAAACCACTCTGCAACCATACGAATTCCAATCACAAACCCGCAACCAACAATACTCAAAGCTAAACGGCTAATTACCAATTGGGTAAAGTTTTGAGCAAGTGCAAAGGTAATACAGGGTATAGCTGCATATATCAGCAAGCAAGAATAGGTAATCCGTGGTCCCAACCGGTCGAGAAGCATCCCTATAATAATCCGTGCGGGAACCGTAAGAGCAACATTACAAATAGCAATGGTTCTAATTTGTGCAGGCTCTAAACCAAATTCCGTCTTTATCGCTGTCGCAAAAGGAGCAAAATTAAACCAGACTACAAAGCTTAAGAAAAAAGCAAACCAAGTCAAGTGTAAAATGCGATAGCGACCGCTAAAGGAAAAAATTCCAGACATAGATAATTACTACTATAAAGGTTGTGAACTGCTGACACTAATTCCGTTTAAGGTTATTCAATCTGGTGTAAATAATATGACGAGGCGCTTCAAATACATTGTAACAAAATTTACCGTATCGCTACTTGTAGCTGTTTGAATGATTTTTTGGAATCCTATCGATGCAAAAACAGGATTTAAGCAATATTTAGAGCAATATTTAAATAATAAATTTATTTTCGACACAAGAATTTTGAGAATGGTGCTGCTGCTGTGAGCATGTAGTAAGCAGTTACGAGATGTAACCTAAAAAAATAAAGAGATAGATGACCTCTAATTAGCAATTTAGAAATAGTATAAATACTTAAAAAGATATTAATTAGTATATTTTATTTAAAGATAACTAAGTATAAAATTGTTGATAAATAGGTTAATCGAATTTATGATTATTTGAAAAAATGATACAGATGTTTTAGTAAATCATCTTTACGAAATTATTAATCATTATTTAAGGAAAATAAATAAATTCAATCCCAATCTAATAAATCATAGTGTTATAAAAAGAGGATTGATAAATTACTATTTTATTTAGTAGATTTAAATCAATCAGATAATAAATGATAAAAAGCGAGGATATAACCATGCAAGCAATCAAAATTAAACTATCAATTTTAGTGGGCGTATCCATGCTACTTTTAATGCCAAGTGTAGCTACAGCCAATAATAATTCAGCAGAAGAATCTATTAATTCTCAATCTTCATCCCTTATTTCTAGTTCTTCGTGCGGACGTGGTGATAGGTGTAGACCTCCTGCTTAATGGATATTTGAGGCTACTTTACTAATTTATAAATTTACAACTAGTCAATCATCCCCAGGTAGTTTTATCCGCCTGCGGGATATTTTTTTTGATAGCTAAAGCCGCATTTCCCCGTTTTTGGTTTCCTAAGCTGCTAGGCATTTAACTTATATATTTATTTGGCATTGATTAACGGCTACAACCCTTGTCCCTTCTTCCCTTTTCCTTCTTCCTTCTTCCAAGAGTATTGTGCATTTCTAATGCACAACAGCTTATTCCCTTATGTTAGTTTATCTCTACATCTGGGAACTCTATAAATATTACCTTGGCAGACTCATCGAGCTAGTCAAATAGTTATTAGAGAAAAATAAATGCGCGATCTCCACTATATATTATTAGCTTTATCAGTCACCTTTTTACTTTTACCAGTTTCAGAAGTTGAAGCACAGTTAATACCTGATAATACTTTAGGAAAAGAAAATTCTCTAGTTAATCCCGTTAATTCAGTTCAAAGGATTGATGGCGGTACGATTCGTGGCTCTAACTTATTTCATAGTTTTCAAGAATTCAATATTGGTAGTGGTAAGAGCGCTTACTTCAGCAATCCGGGTAATATCGAAAATATTCTGACTCGCGTTACGGGAAAAAATTCCTCCCTAATTTTGGGAAAGTTAGGAGTATTGGGTAATGCTAATTTATTCCTAATTAATCCTAATGGAATTATTTTTGGTGAGAATGCCCAATTAGATATTAATGGTTCATTTGTTGGCTCTACAGCAGATAATATTAAATTTGCTGATGGCAGAGAATTTAATGCAGTTAACCCCTCAGCGAATCCGATTTTGACTATAAATGTTCCTTTGGGTTTGCAATATAAAGGTAATGGCGGAAATATTGAAGTGCGCGGTACAGCAACATCGAATTTAAAAGTACCAGATAAAAAATCCTTAGCCCTAGCAGGCGGAAATATTAAATTTGATGGTGGGAAACTAACTGCACCAGCAGGCGGAATTGATTTATTTGCAGTCACTAACGGTGAAGTTTCTTTAGTTAATAGTAACGGACGAATAAATTTAAAAACCCCTTTAGGTATTGAGTACGGTGATATTGAGTTTTTGAATGCCTCTAATATCGATGCCAGCGGAAACAGTGGAGGTTCTATTCAGGTACGAGGTAGAAATATAAGCCTGAAAGGAAACTCAATTATTTCTACAAATACTGATGGAGATGGCTTTGGAAAAACATTAAATATTACAGCTACAGAATTACTTAAAATAAGTGCAAGCGATTTATTCGCGGATGTCCAAGACAACGCAACTGGAACTGGTGGCGATTTAGTTGTTAATAGCAAAAACTTGATAGTTACTGATGGAAGTATTCTATCGAGTAGCACTTTTGGTTTGGGTAATAGTGGTAATCTAACTATTAAAACAATTAACTTGCAAGTAGACAATGCAGGCAGAATTGATGTTACAACTTATGACTTTGGTAATGGTGGTAATTTAACTATTGAAACAGCTAACTTGCAAGTATACGATGGGGCACAAATTACTGCGATCGCTTTTGGAAAAGGAAATGCTGGTAATATGGAGATTAAAGCCAATTTAGTAGAATTGGTTGGTTTTAGGCAATCGAGTGATATACCTCTTAAAAGTGGATTGTTTGCCAACGCTCTTCAAGAAAACGGGCAAGGTGGGAATTTAAATGTAACAGCTAATCGGTTAGTTATCCGCGATGGAGCAACTATCAACGCTAGTAATTTTCTCAGCTTCGATCCCGATAATCTTCTAGGTAGAGCTGGTACCGGTGCAGCAGGAAACATTGATATCAATTCGCCATTTGTTCTATTAGAAAATCAAGGCATAATTACAGCAAACGTCAATGCTGGAGACAAAGGTAATATCAATATTCAATCCCAAAACTTGCAGCTACGAAAAGGAAGTGTCATTTCAACTAACGCAAAAAACAGTGCAGATGGTGGAAATATAAACATTGACACAAATACTTTAGTCGCATTAGAAAACAGCGATATTGCCGCTAATTCAGAAGGAAGTTTCGGAGGTAGAGTAATTATCAATGCTAAAGGTATTTTGGGTACCCAGTTTCAACAGCAACTTACTCCGCAAAGCGATATTACTGCAACTTCTTCTTTAGGAGCTTCTTTTAGTGGTGTAGTAGACATTAACACCATCGCCGTAGATCCCAACTCCGGATTAATCGAATTACCCCAAACCCTTACTGACTCCAGCCAAAAAATCAAAGCTGGATGTGATGCAACTGCGGGAAACAACTTTGTTGTCAGCCCCAGAGGTGGTTTACCACAAAGCCCCGATGACTTATTTAATGGCAGCACAATATATACAGAATTAAATGATGTAATACCAATACAAGATATAGCTTCTGATATTAACGATCGCAATCATCAAAATTATCGCAATCGCTTGTCAAGCGTTGAGAATAAACATAAAAATCAAAATAAAAATCAAATTGTAGAAGCTACCGGATGGGTAGTTGATGGTAAGGGTGATGTGGTATTAGTTGCAAAAATGCCCCAACACAGCCAAAAGTCTCCCAAAATTAATTCAGCTTCTTGTAACGATTTTTCTTCTTAACTGTTTCCTCGCTTGGGCTGCACCTCCAAAACATCTATATACAAAAAATATTTCAAAGATCGAAAACTTTCTTCAAACGCTTGCGAACCCAAACTACCGGATTAATATCATCTTCCGACTCATCAATTAAACCCATTTCTCGCAATTGCTGCTGACGGGAAGTTAATTCTTCTTGATGCTTCGCTAACTCGTTAACTATTTCTTCCGCCAATTCCGGATTACCTTTTAAAAGTTTTTCAAAACCTTGATTATTAATCACAAATAAAGTTGTATCTTCTAAAGCTTTAACTGTCGCCGTGCGGGGAATTGCTAACATTAAAGCTAACTCTCCGAAAAATTGTGCTTTTCCTAGAGTTGTTAGATGTTTATTGATTTTTGAAACAAAAACTTCCACTTTACCAGATAAAATAATATAAAAAGCATCCCCTGGATCATTTTCTTTAAATAATATTTCTGACTCTTTTATTTGCTGACGATATCCAATCTCTAATAATTTGCGTAAATCTAGGTCGTTAAAATTTTGAAAATATATAACCTGCCGTAATAAAGTTCTTAAAGATATTTTTTTTTGCTGAGTTTCAAATTTGTTATATTGAGAATATAAAGAAAAACTCTTTTCATTTACATATCGATTTGTAACAAAATAAATGCCCTGGCGGCGTAAATTGTATTCGATAGCATAATTTAAAATACTTCTAACATGATTTTTATCCTGAATTTGATTTATCCATACTCTCAAATCAAAATCTAAATAACCATTAGCAAAACCGTTAAAAATTACCTGCGGGGGATTATCTTTAGCGACTAATGGCTCCATGTAAGCCGCATCAAGTAAAATTTCAGTAACTATTAATGGGTCATTTCCGTATTCTATATTTATTGAAAGACAAATTTGTACATTACTATCGTTGTAAGTACAATTAAGAATAGGTTTTTGCACCAATTCGCTATTAGGAATAATTAAACTACTACCATCAAGAGTTTGGATAACAGTAGAACGTAAAGTAATTTTTTTAACTCTTCCTTGTAAGGTTTTAAATTCTTCTGATATCCATAATTCAATAATATCGCCAACTTTAATAGAACGTTCAACTAATAGAGTTAACCCGCTGATAAAGTTCGCAGTTATATTCTGAATACCGAAGCCAAGCCCAATACCTAAACCACCGGCTAATACAGCTAGAGAAGCTAAATTAAAACCCGTACTTTCCAGAACAATTAGAAAACCTAACGAGCCAAAAATATAGGTAAATATTGTTGCAAGAGCTTCTCTGTTACCTTCATCTATGCCAAAATTTATAAGTAATTTATTTTTGAGTAAATTATAAAGAATTCGACAAAAAATAATAACTACTACAAATGAAAAAACTAGCTGTAGTAGCGATGCGAAGGATATGGAAGTTTCTCCAATTTTTAAAACAGGTTTCTCCAAAATTTGAGATAGCTCTAATAATATTTTCTCTATAAATATTCTCATACTTGTTTCAGCCCGCATAGGCGGGCATGTTGGTAGTAGATTTAATCTATTATCAGAAACTTATAACTTCTAAAGTATCAATAATATATTTAGCTGCTTCCACAAAAACCTCATCCATATTTTGAAATTTATCGGGATGAATTAACGATTGTAACTGATTAAAAGTTTTTGTGTCATCAATACCATCACCACTAAAACCGCTTTCCAATACCGCTGTATATTTATGCTCGATATCCAAGAAATCAGCGGCTTTCTGCAAATATTTCTTTTCCTCAATCGAGATTTCTCCATCTACAGCAGACATTTCATAGCAAAAACTCATCATTAATATTTTTTCCGATTCCGATAAAGATTTCGCGAGTTTTAACCATTCTTGAGGATGTTGATAAATACCAGTTTGCGGTACTTTATTGACTAAAGTTTCCATAATTTCCCGCATTTGCCTGTTTTTATGAGGAATTAAACGCTTAATAGTCTTTGCTAACAATTTCTTTTCAGCTTCTTCCTGCATTCCATCAGCTTCAATCACACCCCAAGTGATGATAAGTAAAACAGTTAAGAAAATTAAAGTATCGTTAATATCGGTTTTAACAAATTTTTTATCTGTCAAACTAGATAATAACTCTACAGCATCTAAGCTGACAAAACGCAAATTTAAATGGCTAAAATTTGGCGGAGAAATAAAATCTTGTAACTCATTCCAAGCCGATTGTTCAACTTTTTTTCCACTATACCAAGCTTCTAATACTTCTGTATATTTAGTTGATACTTTTAGAGCATTTCCTGCCGCTTTTAAATATTCTTTTTCGCTATCATCAATATGTCCATCTACCGCCGACATTTCGTAAGAAAAATTCATCAACAAAGTTCTTTCTTGTTGTGATAGACTAGCCGTCAACTTTAACCATTCAGAAGGATTCTGGTATACCGCATTTTCTCGGTTGCCATCAATTAATTGTTGAATTAATACTGTTACATCACCTTTTGATGGAATTAATTGATCGATAGTTTTTTCTAATAACTGTGTTTCCGATTCTGTCACTACCCCATCAGCAAACATAACTCCAAAAGTCATGGTGATTAATGATGCTAAAAACATCAATTCGGGAGTTACTTGCTTATGATGTAATTTTCGTTTTGTCAAACGGGATAATAACTCAACAGCTTCGGAACTAACTAATTTAGCATCAGAATTTACTGCTTGTTTTCCGACTATATTTGAGTCAAATATTACTGTATTCATATACTTAACTTCCTCAAAATGAACATTGATAAGAACGCACCCAAAAATGAATTTATTTTTAAAGCCAATCAACCGTTGCTTTTAGACGATCCTTCTGTAGTTTGGATGATTGAATCGGGAACTGTAGCGCTGTTTGCAGTTGTAATACAGGATGGGATACCAGTAAGCGAACGTCGTTATCTTTTCAGTTGCAATCCTACAGAGGCATTATTTGCCATCGATTCTACTAAGGTTAAATCGATAGTTACATCAAACGATAACAATGACCATCCGAAAAAATACGGGATATTGGCTGTTGCTATCGAGGAAGCATCTTTAACTCAAATCCTTCAAGACGACTTTGAAGCTTTGAGAAGTAACGATTCGACTCGACTAATACCAAAATCTGCAGGAAAAGAATTTATTCAACTAGCAGAAACTTGGATTGAGAAATTTTCGATTTTCCCTGGTGTCGTTAATGCTTCAAGCATTTTTGATACTTCGGTTGCATACACTTGGGATGATGCCTCAGTTTTGCATACTTGGGAAAGGGTTTCAGAAAAATTAGGACATTTGCACAGAGATTTTCTGCGCTATTTTGAGAAATTAGAACAAGATGAAAGCCAAGAAAAGCTTGCTCAATTTCAAGCAAGAGAACAGCTTAATCGTCGAGTTACCGAGACTTCATTAAGGGAACTAGCTTCCATATTTAAGACTAAAAGTCAAGGGTTTATTCAAGAAGACAGCGAGCTATTAATGGCTGCTGGTGCAGTGGGAAGAACTTTAGGAATTACGATTCGACCTCCCGTAAAGTCAGAAGACTTAAACCGCGTTAAAGAACCGATTGAGGCTATCGCAAGGGCTTCTCGGATTCGGATGCGTCGCGTCATCCTAACCCCTAATTGGTGGAAGAAAGATGCTGGTCCCCTGATAGGTTACGTTGGCGAGGAAAAACGTCCTGTAGCTTTATTACCTGCTAGCAGCGGTAATTACGATATCTTCGATCCGAAAATCTGCAAACGAATTCCTTTAGAAAAGTTTATTGAAAATGAAGAATTAGAACCTGTAGCTTATATGTTTTATCGGTCTTTACCCGAGAAAGCATCTAAAGCCATAGAACTGATTAAATTTGCAGTTAGAGGTAGGCTTAAAGATTTAGCTGTAGTAATTATTGCAGGTGTTATTGGTACCTTATTGGGTATGCTAACTCCCCAAGCTACCAGTATTATTATTGATAAAGCCATTCCCGATGCCGACCGGGGGTTATTAGTGCAAATTAGTTTTGGTTTGTTAGCAGCAAGCTTTGGTACTGCTGTATTTCAACTAACACAAAGCTTTGCTTCATTAAGATTGGAAAGCAGTTCGGACGCTACCACTCAAGCTGCTGTTTGGGATAAATTATTAACCTTGCGAATGTCGTTTTTTCGCGCTTATTCTATTGGGGATTTGCAATCGCGAGTTTCAGCGATTAGTCAGATGCGTCAGTATCTGAGCAGCAGCACGTTACAAACTATTTTTACCAGCTTCTTTTCCCTACTAAATTTAGCTTTGTTGTTTTACTACAATTCCCGCTTGGCTTTGGTAGCAATAGGTGTAGCAGTTGTCTCAATAATTATTACTAGTATTTCTGGTATTATCACTCGACGCAAGCTGCGTCCTTTAGAAGAAATACAAGGGGATATTTCCGGTTTGATGGTGCAGTTAATTGGTGGGGTTTCTAAATTAAGAATTTCAGGAGCAGAAAATAGGGCTTTTGCTCACTGGTCTAAGAAATACACCAAACAGCTAAAGTTAATGTTAAGCAGTCAATTGATAGAAGATTTGGTTGGCTTATTTAATATCTTAATTCCCACCATTGCTTCCATAATTATTTTTGCTTTATCAGCTAACTTAATGTTCGGGGCAAATACACAGAATCCTCAAGCTTCTCCACCTTTAACTGCTGGAACTTTCTTAGCATTTAATTCTGCTTTTGGAACTTTTATGGGTGGTGTTGTAGGTTTAAGTAATACAATTATTTCTATTTTAGAAGTAATCGTTTTATGGGGTCGTGCAAAACCAATTCTGATAGCTACCTCTGAGATAGATTTGAGTAAAGCTGACCCAGGAAAACTAACTGGTACAGTAGAGTTAGAACATATATCTTTTCGCTATCGAGAAGACGGTCCTTTGATTTTGAATGATGTAAATATCAAAGCAGCAGAAGGAGAATTTATTGCATTTGTTGGGCCGAGCGGTAGCGGTAAATCTACTATTATCCGCTTGCTGCTAGGATTTGATACACCGGAAGTAGGTACAGTTTATTATGATGGTCAAGACTTATCCGGATTGGATATATCGGCAGTCCGTCGTCAATTAGGCGTAGTATTGCAAAACGGAAGAATTAGCAGCGCTTCAATATTTGAAAATATCTCTGGTGGTGCTTTAATTACTATGGATGAAGCCTGGGAAGCCGCTCGAATGGCAGGATTTGCCGAAGATATTGAAGGAATGCCAATGGGGATGCATACTGTAATATCCGAAGGTGGTACCAATCTTTCTGGAGGACAACGGCAACGTTTGTTAATCGCTCGTTCTTTGGTATTAAAGCCCAAAATTTTGATTTTTGATGAGGCAACTAGTGCTTTAGATAACCGCACCCAAGCAATTGTAAGTGAAAGTTTAGACCAGCTACAGGTGACACGCATCGTAATTGCTCACCGTCTGAGTACTATCCGCAATGCAGACCGCATTTATGTAATTGAAGCTGGGAGAGTAATGCAACAGGGAAACTTCGAGCAACTTTCACAACAGGAAGGTCTATTTGCAAGTTTGATGGCTAGGCAAATGGCTTAATGATAAATACTTAAGAATCTAAGATTTTAGGGGTAAGTACAGAAAAATCAATTTTAAGCGTTACTTTGACTAAACTTCTGGGAACAATCAAGGAGTATGCTTTCCAACTATTGAATTAACCAGACGCAATGTTAGCAACTGAACCCCTGAAACTGGATTCTTACTTACGTACTTTAGTCAATAAAGCAAGTTATTTAACGGAGCGTCTCAATCAAGATGTTGTTCCTACTGTCTCAAAATCCGATGAATCCACAATAAATTCTCATCTGGAATTTTGGTGTCAAGTTCTTGCTAAAGGTAATAAAGAACAGTTTCAACGGCGTTTAGCTGCTGATAAATTAGATATAGATAAATTGCATACTCTCTTAGGAGAAGTTGAATATCCTCAGTCTCAACCTCTACCTGCTTGGGGGCAGACTTTAAAATTAGTTCTGCAAGCCGCCCAAAAACCCTTGAATACAGAATTATCTGACTTTTCATCAGAAAACCCAATTCCCTTTGAACCGTTTTATCAACCTTTTATACAAGTTGCTCAAAATCAACTTTTATCTCGCGTAGATTTAGATATACTCGGTGAAGACGCGCAAAAAACTTTATGGATAAGTTTACTAGATCGTTTAAGAAATATTGCCATTAAAACACTGTTTACAGAATTTGCAGAATTTCGTTCTTCGGGAAATTCCCTAAAAGATTTTTTCTTAATTCAATTGCAAGGCAAAAATAGCCAGGAAAAATATCATGCCTTTTTGAAGCATTTATTTCAAGATGGCTTACTTGGTTTATTTGAAAAATATCCAGTTTTGGCAAAGCTGTTAGCTACTGCGATTGATTATTGGGTAGATGCAACTGTAGAGTTTATTAATCGTCTGAGAACAGATTTGCCAGCAATTGAAAAACTATTTTCACCAGACACAGCCTTGCAAAAGGTAGTTGAACTAAAAGCTAATTTATCTGATTTGCACAATCAAGGGCGCTCTGCAACTGCTTTAACTTTTGATACGGGTTTGAAATTAGTATATAAACCCAAAGACGTAGAAATGGAATTGGCTTATAACAAAATAATTTCCTGGTGTAACGAAAATGGCAGTCCTTTACCTTTAAAAACTTTTACCGTTTTATCTCAAGCCAAATATGGATGGGTGGAATTTGTATATCAAGATGATTGTCCCGACGAAGCCGCAGCAGAACGTTACTATCAAAGAGCGGGAATGATTCTAGCTATAATGCATTTGCTTTTAGCAACCGACTGTCACCACGAAAACTTAATTGCTAGTGGAGAACATCCAGTACTAATAGATTTAGAAACATTATTGACTCATCAGACAACAAAATCTCACGATTCAAACTCCGAAATTCCTCAATCTGCATTCGATATACTCGACAAACAATTAGAAAAATCTCTGATTCGGACAATGCTACTCCCTCAAAAGGGTTTAATCGCAAAAGATTCTGTTGAAATTGATTTGAGTGGATTCGGAGGAGTCGAAGAATATAAAAGTGCTATGCCGAAGCTACGGTATGTTAATACCGATGGCATGAATATTGCTTATGAAATTATTAGTATTGAAAGTCATGCTAATGTTCCCAAAGTCAATGGAGTAAATTTATCTCCTCTTTCTTATGTGGAAAGTTTGGTGACTGGCTTTGAGCAAATGTATCGCTTCCTTAAGAACCAAAAACAGGCTTTATTAAAACCAGGTAGCCCTTTAATGGAACTAGCCAATCAAAAGGTGCGCTATGTTTTTCGAGCAACTCACATTTACCATTCTATTATCCAAGATAGCTATTCTCCAGAATACTTAGATTCAGGGATAAAACGTAGTTTAGCCTTAGAAGTATTAGCCCGCGCTTTCGTTGTTAACGAAGCAATGTTAAATAGAATCAGCATTTTAAATGCAGAGCGTCAAGCTGCCGAAGATGGTGATATTCCTTTTTTTGCGGTAAATACCAGCGAATCTAATTTACCTTTACCAACCCAAGAAGTTGTAACGGATTTATTTATCCAACCAAGTTTTACAGCAGCTATCAATCAACTTGAAAATTTGAATCAAACTAATTTAGCTCAGCAAGTTGCTGTAATTCGAGGGACTTTTGCGGCTCGGTATACTAAAGAACCTGCACTATCTGCAAATTCTGTGGCTGTAAATTTCAAGGAAAATCTGAAAGAAGATGTCATAGCTCCCGATATTTTTGTAGAGCAAGCAATTACTTTAGCAAACGAACTGAAGCAGACAGCAACCTTTGGTGAAGACGGTAGCGTTGCTTGGTTGGGTTTAGGCTACAGAACTACAACCGAAGGTTTTCTTTTTCAGCCTTTAGGTTCAAATTTATACGATGGCAATTGCGGTATAGCTTTATTTTTGGCAGCTTTAGCAAAAATTACTCAAGACTCACAATGGAGCAATTTAGCATCCCATTCTCTACAACCTCTTTTACAAATACACAAAACAGAGTCATCAGAAAGACTAGCGAGATTTACCAGAAAGATGGGCATTGGTGGAGCAACGGGTTTAGCTTCAATTGCTTATACTTTAGTGCATACCAGTAAGTTGTTAGCAGACAACAATTTATTGACAACCGCTAAAAATATAGCTTTATTAATTACTCCAGAATCAATTGCCTCAGAAAAATATTTTGATATTACTAGAGGTGTCGCAGGAGCGATTTTAGGTCTTTTAGCGGTTTATAAAACTAACCCCGAAGATAAAAGACTATTAGATTTAGCTATTAACTGTGGCGAGCATTTGCTAAAACAGCAAATATCTATAAACGAGTACAAAACTTGGAAAACCTGGAATGGAATTGCTTTGACAGGCTTTTCCCAAGGTGCGGGCGGAATCGCTTATGCTTTATTAAATCTGTGTAAAATCACCGCACGAGAAGAATTTTTGCAAGCAGCTAAAGAAGCGATCGCTTATGAAAAAAGCTGTTTTTGTGAAGAAGCTGGTAACTGGCAAGATTTGCGTACAGAAAATAATCAGTATCAAGTTAGCTGGGCGCATGGTGCTGCCGGTATTGCCTTAGCGCGTATAAATAGCTTATCTATACTCAACACTCCAGAAATCATTGCAGAAATTAATACAGCTTTAGAAACTACCCAAAAATGCGGGATTTCGACTGTAGATAATCTAGCTTGGGGTAACTTTGGACGCATCGAAACTTTACTAGTTGCCGCTCAAGTTCTTAACCGTCCGGAATTATTACAAATAGCTCGCAACTCAAGTATAAAATTAGTCGAGCAAGCCCGAGAAAAAGGCGGTTTTAGGCTTTATTCTAATATACTAAGTCCAGTATTTAACCCAGCATTTTTACACGGTACCAGCGGTATTGGCTATCAATTATTACGTTTAGCATATCCAGAATTACCATCTATTTTGAGTTTTGAATTTTAATAAATAATAGGTAAGGCACTACCGTAAATTGCGGAATAGTGCCTTATCGTTCAAGCTAGCAAAATTAAAAATTAAAACATTTCTAATTAGATAGAACTAACGATTGCATTTCATTCAATTTGACAGGTGTATAGAAAAAATATTCATATTATTCTACCCCCTCTACCTTCTCTCCCCCCTCACTCAATCTACAACTAAAATATAAATATTCTCCATTAGAACAGCTTTAGGTAATTTTGATAAGAGATATACTCACTATTACCTTCTTTTTGAATCGGTGGAGTTAAATAATTCAGAAATAACTCTAAATCTTCAGTTAATATATTTTTTTCTGCTGCTATTTGAATAAGTTCAACAGCACAATCAGGTAAACAAAATATTTCCATCAAACTTGCTAACTTTAATATTTTTAACTTATTCCATTTGTTAGCGGATTCCTTTGTTTCTAATTCATTCACAGCATCTCGTAAGTATAGAGCCTGTGCCCATAAAACCTGTCCTTGCTTGGTATTTCCCAGCTGTGAAATCATCGGCAAAGGTAAAGCTTTTCTGGCATGTCGATATGTTGCCAAATCAAAAAGACGAAATCCCAAAGAATTTAAAAATAAATCGATGTGACTGAAAGTTGGCTGATTGCGAATAGATTCATGAAATAATACTTCTATACTTAATCCTAGGACGGATTCATTTAAACAACTAACCGCACCTTTTAAGACATCTAATTCACTTCCTTCAACATCCAACTTAATAAAATCAATTTCATCAATTTTATTATCAGCCACAAAAGAATCTAAATCTACAGTTTCTATATCCAGAGTTTTTACTACTTCCATCATCTCTAAATTATCATGGGGGAAGCGCTTCAGAAAATTTTTATTTCCTGGGTAAAAACCTGATGAACCTCCCCACTGACAAAATGAAAATGTCCGCTTTTCTCTTTTTTCACCTAAAGCTACTGCATAAAATTTACTGTTTCGATTTGGTTGCTGATTCAGGCGATCGCACTCTTCTTTGTCAGGCTCAAACCCAATTTTATAGACTTGTTCCCCATATGATTGCCAGTGATGTTCAAAACCTCCTCTTGCTCCTATATCCATAACTAAAAGAGGATTTTTGGAAAATGTTTTTTTATTAACTAAAAATTCAGTCATTGTCGGCTGGTAATTGATATGTTTCAGTGCCATAATTAGTATTTATTGGTAGGACTTTTATTTAGAGTTATATGATTTAACGGTCATTATTGTCATTACAAATCAAAACAAGACTTACTTTCAGCAAAATTTCGATATTTGTAATGACAATAAAGCAATAATTGCGTACTAACTTCTAGATATTAATTTACTAGATGGGGTACAGATATTTTTTTCAGGATGACGATATAAATCACCGTAAATGTTTAGATATTCAATTTATTCTGAGGTAAATTTACCCTTTCGCATACATTTAATTGCAGCATCAATTGCTTAGATTAAATAGCAAATATAAACTGTCTAACTTATAAAAATAGAGTTAGGCAATTTATTTATTGTGAAATTAAAGCCATGCTTTGCTCCTAAATATACAACCGCTTGACGGTCATTTTCTGCCTGCGTTGCTTGAGCTAGTTCTTCTTGAATTTGATTATCCTATCCAACTTTATCTAAAAATTGATTTACTGCTTAAATACTCATTATTTTCAACTCCAACTAATTTCTAACTAGTTATTTAATCCTTTTTATTTCCTTCTCCAAACTGTTGGAGAGAGGATGAGAGTATGTCTTGAGCTAAGTTTGTTATTAACTTATTAAGCCTTAGCTAAAAGCTTATACCATTTCTTTATAAAGATGCGCCTAATTTAGCCCCTGAAGAGGGGCTTCGTTTGTCTAGCCCCACTCTTCCAGAGTGAGGGCTTTTAGCGCAGCCTCATACAGAATTGGTATTACCATTTCGCTGTGGGCAATTTGGGAAATGTGGGTAGTGTGGGGATGTGAGGAAATATTACGGTAGTAATTGGTACTATCGTGGCTTTTGCACCACCAGCCACAGCTTCTAATTCTTCTTCATTCAATTCACCAGATTCAATAGCAGCTTTTTGACGTTTTTCAATTTCAGTCATTAGTTCATCGCCAGTGAACTCAAAGCCATGTTTTGCTCCTAAATCTACAACCGCTTGACGGTCATTTTCTGCCTGCATTGCTTGGGCTAATTCTTCTTGAATTTTGCTTTCTTGTGCAACTTTATCTAAGAATTTATTTACTGCTTCGATACTCATTGTTGTTACCTATTCTAATTTTTGTAATTAAAGATTTAGTCAATTCAATATCAAAATTTTACCCATTCTCTATTGAGTTTCTGTTGAGAAAAGAGAAATGGAATAAAGTTGTAATATTGTATTAAGTCAGATTTACTTGCCTACAATACTTACCACTTTACTTTTTTGGCTATTGTTACAACAACGGGGGCGGTAGCAGTAACAATCGGTACAATCGTCGTAAATGTAGGAGTTGCTCCACCAGCAACAGCTTCTAGTTCTTCTTCACTTAGTTCGCCGGAATCAGCAGCAGCTTTTTGGCGTTTTTCAATTTCATTCATCAGCTCGTCGCCAGTGAAGTTAAAACCATGCTTTGCTCCTAATTCCACAACCGCTTGACGGTCGTTTTCAGCCTGCATTGCTTGAACTAATTCTTCTTGAATATTGCTATCTTTAGCAACTTTTTCTAAGAATTGATTTACTGCTTCGATACTCATTTTTATTAACTCTAACTGATTATTTGATTCTGCAAACATCCCTCTCCAATACTTATGAAGAGGGGATGAGAGCGAGTTTCGGCTTGAATCTATAATTAAGTGACTAAGCCTTATCTAAAAACCTTACCACTTGGCTTTATTGATTGCTGCTATCGCTATAGGAGCAAGTGCGCCAATGAGTGGTATTATGGGAAACGCTCCACCAGCAACAGCTTCAAGTTCTTCTTCACTCAATTCACCAGACTCAGCAGCAGCTTTTTGACGTTTTTCAATTTCAGTGACTAGTTCGTCACCAGTGAACTCAAAGCCGTGTTTTGCTCCTAAATCTACAACCGCTTGACGGTCATTTTCTGCCTGCATTGCTTGAGCTAATTCTTCTTGAATTGTGCTGTCTTGTGCAACTTTATCTAAGAATTTATTTACTGCTTCAATACTCATTGTTGTTACCCTATGCGATTGCTGTCATTAAAGATTTTGTTTGAGTTGGCGCTTTTGTGTTACATCGAATTGATTGTATTTCGCCGAACTTCGTATCCTATACTATGTTCTTTTTTGGTGGCAATTAACAGTGTATTTACTTATTTTGTATATTGGCAAAAAAGTAAATATTTTCAGACTAACCATTCTACTTTTGGAGGGTTGATTATGTATTCAATGGTTAGACTTGAGGAATACCATGCCAATCAATTGAACATAGCCCTTTTCCCTTGAGTGCATATATGTTCTCAAGCTACCTACACTAATCAAATAAAGATGCCGAGGAGAGAACTCATCCTTAAAAGCTCAGAATTATAAGCAAAAAGCCAAGTTTAATAGCTTACCACTTAGCTTTAGCAATAACACCTCCAGTTATACCAGCAGTCATGGCAATTCCTCCTGCCACGAAAAAGGTTGTAGCTGGGGTAGCACCACCTGCAACAGCTTCGAGTTCTTCTTCACTCAGCTCACCCGCATCAGCAGCAGCCTGTTGGCGTTTTTCGATTTCCTGCATTAGCTCATCACCAGTGAAATCATAGCCTTTGTTATTAGCCAACTCTGTTACAGCTTGACGATCGTTTTCAGATTGCATCGCTTTTGCTAGTTCTTCTTGCAGTTGGGCATCTTCTGCAACTTTGGTCAAAAATTGATTGACTGCTTCTACACTCATGAATGATAACCTTTGTAAATGAACTAAATGCCAATATTGATTTTGCAAAAGTGAAGCTTTTTACTTTATATGCAGCCATATATTTGTAGTAGTGAATAGGCTGAACTATAAAGAATTAAGTTACCACTTTGCATAGCGTTTTATTACTGCTCCGCCAATTGCGCCACTTGCTCCCATAATAGTGACGACAAGCGCTCCTGCTGGGGTAGCACCACCTGCAACTGCTTCGAGTTCTTCTTCACTTAGTTCCCCAGAATCGATAATAGCCTGTTGACGGTTCTTAATTTCCTCCCAGAGTTCATCTGATGTGAACTGAAAGCCTTCTTGTGCAGCTAAATCGGTAACAGCTTGACGGTCATTTTCAGATTCAATCGCTTTCACCAATTTTTGTTGTAACTCTGGATCTTCTGAAACTTTTTCAAAAAATTGGTTAACTGTTTGGGTACTCATAATTACTATTAACTTTTCTGTGTACAAAGACGGTAATCAAATCCTGTCCGCTATTTCTACCACTTGATGAATAACAGCAGGATTACATATATCATCATACAAAGCTCTACACCACAAAGAGCAACAGTATATTTACTTAGGTTGTATCTATGTAAATCCCGCTGCTAAAATTTTATGTAAAGTAAAAAATAAGTAATTACCACAGTTGCCAATTATTGTTTTAATTTGAACAATTAGTATTGTTACGTAATTATCATTTCAAGAAATATAAAAACTATAAATTTGACACAGTAATTTTTTATTTACATTACTTCCGTACAATACCGGAAACAACAATTCTGTTAGTACATATACAGGAGTTTGAATGAACAATGCTATTTCTTTCAGTCAAGGCTCGCAGATTCGACCGTTTAACGTTAACGACAGAGTATGTCTGGCTATTCAACCCTTTATTCAGGAAGTACTCAATCGCTTTGTAGAATGCCAAAATTTAGGTGAGTCTATCAAAGCATCAGTAGAAAATCATCAGGAGATTGTTGAACAAGCCTTTGAGATAGATAACCATAAGATTGAAGAAAGCTTTACCTTAAAACAAGAATTTCTCTTTCCGGAAGAAAACCCTTTATTGTTCATATCCTATGATAATCCCAGCTTTCTACCTTTCCTAAATAAAAAAGGGGTGCAATCAATTAAAGATGAATCCATTTTGCCTGATATTCATCAATTACTTTATTCTATTGGTCAATCTAAATTCACTTATCAGCAAATTAAGCAGCAAATTAGCGAGCCAATGGTAGATTTGCTGGATAAATTGATTAAATCCAGCGTTGTTAAAGAAAAACCTGCTGTAGACATAGGAGTTCCTTTAAATACTCCCGGAGTATTTCGATTGCAGCACGCATCGGTATTGTATAGGACTAAAACAACAGGTATATTAGTTGACCCACATTTGCATTCCAACTATGGTATTCCAGGATTAAAATCTGATATTAATCGCGCTCAATTGGAAGGTTTAGTTGATGGTATTTTAATTTCTCATCCTCACTACGATCATTGGCACTATCCTACCTTGATGATGTTTGCGAAGGAAACGCCAATATTTGTGCCGAAAGTGCCTCGTGCTTCTATTATGTGCGAAGATATGGCAGGACGACTAAAAAGTTTAGGATTTACCAATGTGATTGCAGTTGATTGGTATTCCGAACCGATTAGAATCGGGGATATTAATATTAATGTTTTACCTTTTTATGGAGAACAAGCTTTAGTACCAGAATTTGATAAGCCCAAATATCCTGAATTAAGAAATTGGGGTAATACCTATTTAATTGATACTGAATTTTATAAGTCATGGCTGTTAATTGATGCTGGACAAGAACCCAATGGTTCCATGATAGAAGTAGCTGAATACGTGAAAAATAGTTTCGGTTCTATTGATTTGCTTATCAGTAATTTTCAGCCACTATCCTATAACTCTATTGGTACGAATTTATCTGGATGGGGAATTGATATTGTGGCAAATTTACTTAGCAATCCTCAAATATTTTCTGTTACGAACAAACCTGAAGGAGCCTATATTGCTTTGTTAGGACCAAAAGGTGTGGCAGAAGTTTGTAATATAGTCAATGCTTCTTATTGTTTTCCTTATGCAGATAGTTGGGCAGAAGCTGGAAAATCAGGAATGCACGATGAAGAATTAATTCCTCAAGTTCAAGCTGAATTACAAAAAATTGGCTGTTCTACTAAAGTTATTCCTTGGAAAATTGGCGATGGTTATGTAACTCGTAATGTTACGGAATGGAATCTAGAAGCTGGTAATTGGTATATGAATAATTGATTTATATTTAGTTACTAATTACCAATTCCCTCTTTTCACAAAAATTGTAAATATTCAAAGGAAAATGATATCTTCAATTCAAACACAAAAAAAATGTTATTCACAGCGAAAAGATGCCTTTTCTAATGAATATTTAGAATTTTTAAAGAAAGATATTCTTAATAGTCCTTATTTAGCAGCCAGTCAACTAAGTGACGGATTTGTGGAAACTCAAGGTTTTTCTGTTGTATTTAAACGCTCAACAATAGCTGAAGTGGAAAAAAAACTTCCATATTTTAAACCTTATTTAGATACAGCTTTAAAATCTAGCTGTAATGCGTTTTATTTAAATCCTCTGATTTTGAATAGCGATACTTACGTAGAACCTCATGTAGATTGCAGTATATCTGAGTATGGCATGGAAATGGTGATGCCAAATTTAGTTAGCGTACTGTATGTTCAAGTTCCCTCGGATTTAAAAGGAGGTGAATTAGTATTACAGCAAAGCGAAGAACAGGTATGGCAAATTACCCCTCAAATCAATACATTACTTTATTTTCTGGGTTGGATAACGCATTCTGTAAATCGAGTCGAGAGTTCTCATAAACGGATAAGTTTAATTTGCGAGCAATATAATTTAAGCGAATCTCGATTAAATAAAATACCTGATTTTGAAATCAAGTCTGGAAAAGACAGTGGAAAATAAAAATTAGCTTTGAACAATTTTAAATAAAATGCGAAATAATTATGATAGTAACTAATTCTCTGACAGATTATTTAAGTTTATTAAACTCTTTTGTGCCAAGGGAGTTAATTGCAGAGTCAGAATGGAGAAAATTCAATCACATAGGAAATATTTTACCAAGTGCGCTGACGACTTTTTTCGGATTTGAATCTCGTTTGGGAATTCCAGAAGCACATGGTGATTTTCTCATTTGTGCTGATGCTCACGAAGCAGGGCGTAGGGTATTAGCTGCTAATAGTTATGATATTGATTTACCTACTGAATTATTGCACCATCCTGTATGGATGAATATCCGCAAATTTAGTACTAATTGGGAAAGTGAGGCATCACCTCTTTACGACAAAATTACCAATGTCTGGCTAGAATTTGATGTTGGAAATGAAACAAAAGATTTACCAGTTCCGAGTTGCTTTTTTGGACCAAAAAACCTTTATAATACACCTGCTGTAGATTCAGAACATCCATATAAATGGATATGGGAAAATGCTTTACCGCTGTTGTTAGGAAGAAGCTTTCCAAAATCCGTCGAAAACAATATTGTAAAATGTTTTGCGGCATTACCAGAAAATGCTTATGTTTTCCAAGTTGGGTTAATGTTGGCAAGAGAATGGGATGGTGTCAGGCTTTGTATTCGTAATATTTCACCTGAGAAAATTATCGATTATTTAAAGAGTTTAGATTGGCAAGGAGATTTGAATAATTTACAACTACAGTTAAATAATATTTCGCCATTAGTTGACCGTATTGATTTAGATATTGATGTTACCGAAGGTCTCGGTGATAAAATTGGTTTAGAATGTTATTTAAACAAACAGCCACAATTTGAAAAACGCTGGAGTTTGTTTTTAGATAATTTATTATTAAAAGGATTGTGTTTTCCTAAAAAGCAACAAGCTTTATTGACATATCCAGGATATATTCAAGAAAAAATGAATCCTTCTTTATGGCCTTTAAGTTTACGAAAAATTTCTAAAATATTAGGTGATAGTTATGAATGGGTCATATTTAAAGGCATTCATCACATTAAACTGAATTACTGCGATGCAGAAATCAAGGAAGCTAAAGCTTATTTATACGTTAGTCGAAGTTTGATTAGAGGTTGATGAATATTAAATATATCAATCATGTCAAAAAAATAGGTAATTTAATAGTTATTATCAGAATATTATGTTAGTTTCGGAAATCTTACGATTTTTACCAGATTCTTTAGAATGGATGGTTTTATTTGATTTACCAGCTATTCAAAAGTTGACAAATCTATCCACCATTAAGGCAATGTATCACCTTCCGGAGGATATAGATTTAGAGCCTCATAGTCATATTGTTTTGACTAGCGCCGGACGTTTTTTAGCTTTTCAAAATCAGCTAAAATTAGTAGAGGCTATTTCTCAAGAAGAGTTATCGGTTGAACTTACATCTTCTTTAGCCAATCGCTTTCAAAATCGTTTGAAATTAGTCCCGGTAGATGAATCACACTGCTTAGGTTTGGGAGAACAACCTCCTTTTTCACCAGTTATATTGCATCTCAGACTTGAAAATGATTTGGGTAGAGCGACAGCAATTTTTGAACGCGAACCTTCTTTTGAACATTATGAATTGTTGCGAGCTGTAGGTGTGAAATTTACGGGAGGTGAATTAAAAGACGATTATTATTTAGCGCGTTTTCAAAATCGTTTGCCCGTACATATTCACGCTGGGATTCTATCTCATTTTAGCCGCACTGCACACTGCAATATATTTTTCTTCCAGCATGGAAATATTGATAATGCTTTAGAAGATGGTTTATTGAAAGCTTCTCAAGTCAGGATAAATTGGACAAAGCAGCAATGCTTGCAAAGTTTAACGCAATTAGCAACTATTTCCTGCGAAAAAACTCTGAGTATGACTTGTCAACCACCTGCACCCCAAAAACCCTTTGCTTATGGTGATTTAGTGCCTTTAGGATTTGTTCTCAAGGCACTAAATGAGGTGGATACAAAAGAAAATTCAGAACTTGATACTGCTAAACAAAAATTGCAGCAATTCTTATTAAATCAGCAACAAGATCAGCTATGGGCATTTCATACACAGCGATTGATTACCGCTACAGATTCATCATTGGTGCTATTAGGATTGGATAAACCCGAATCTGTAGAAGCTCTGGAGAGATTTTCTGATGGTGAGGGAGGATATTATCCCCAACTGTGGTCAAAATATCAAGAACCGGGTAAAATGCTGCTGGATGAAAGTTGCAGTCATTGGTGTCAACCTGATTATGCAACTACCTGCTTAGTTCGATGGCTGCGGAATTCGGCAGGTTTGGAAACTAAAACCGATTTGGAATATTTAGCTGATGGCTTCTCTCAACGTGCGGGTTTATATTTTGCCAACCCTTACTTAGTAGACTGGATGCTTGCAGAAGCAATTCGCGAAGATAAAAATGCTGCCACTTTACGAGAGAGATTGCTTGTAGAGATAATCGCAAGTATGAATGAGGATTTCTCTTTCGGTAAATACGATGTGGCATTATCTACCGCACTAGGTATTTTAACTTTGGCAGCTTTAGGAGTTAGCGATCGCACTATTTGCGCTGCTCAATTAAGATTGTTGGAATTAATCGGTGAGAAGTCGTCTATTTCGATTCCTTTCTATTCTACTTTATGTCATGATTCAGAACTAAATTCCCAGGAAAAATTGGCATTACAGTTAAACGAAACGTTTACTAGAAGTAAGGATGGACAAAAACAAATTCGTAGCATAAACGGACAACTTCACAGTATTTCTCTTTATCTCGATACCCATGAGATGATTACTACAGCAATATGTGCTTTAGCTTTAGATCGAAATAGCGATTTAAATAAATGGCAGGTTAATAGAAATTCAAGCAATAGTAATTATAGTAATTCTTGCCATCCTCGCTATCAGTGTAAAACTCATTCGCAGTATATAGCAAAGTTTGCTTTGCCACCTTATCTAAAAAAATGTGCTGTAAGTCTATAGATTTGAGGTGAAATTAATATTGCTGGGACAAAATTATCTATAGATAAGGAACAGTTTGAAGGAAAAATTATGCATAACCATAGTGATAATTTTGTTTATCGTAATTTTCCTTTATTTTACTAATGATGTATAGAGAAAATAAAAAAAATGCAAATTCATATGATTGGACATGCATCCATTTTTGTAAAAACTCAGGATGCTAAAATTTTGATGGACCCAGTTTTATGGGACCCTTTTTGCGAAGGATTAAATGAAACTTGTCCTAAACGAGAATTAATTCCGGAAAAACTACCTGAATTTGATTTTCTGGTTATTTCTCATCAACATTTAGACCATTTCGATCTGCGTTCCCTTGCTTATCTTCCTAAAAACATTGATGTTTTAGTTCCTAAAGACGCTCTTATTATCGATAGCTTGCGTCAACTGGGTTATTCTAATATCTACCCATTAAAAGAATTTCAAAAAGTCAGAATCGGTTCTACTACATTGATGACTACTCGTTCCGAAGTCAGAGTACCAGAATTTGGCATGGTATTCGCTGATGATTCGGGGGTATTTTGGAATACTGTAGATACATATTTTGCTCCTCCAACAATTCAAGCCGTGAAGGCAATTTATCCCCAAATAGACTTTTTATTAGCTACTTGGCATATTAGCTTAGAAAATAAGTATCAGCAGAATAAAAATACTGAGTTTCCGTTTGAATTATACGGACAATTAATGAATTTGATTCAATTAGTTGAACCACAAGCTATTGCTCCCGGCGCGCAAGGTTGGAAATATATTAACGAAGCAGCATGGCAAAATCAAATAGTTTTCCCGCTCACAAGAGAGCGTTTTTGCCACGATATCAAACAAGTTTTACCCGATATAAATAATAATATTTTTGTTTTAGACCCCGGTGATATCCTAACATTAGAACGAGGAGATTATAATTTAGAATCAGCAGGGTGCGATTATGTCAAAACAATTGTTGATGATAGAGAATGTTTGGAATTTGCACCAGTAAAAGTAGGGGCGAATTTAATCGATCCTAATTCAGATAGACATGATATTGACTTGATGCAACAGACAATACATCAAGCTTTACGGGTAGATTTATGCGATTTTATTAAAGAATATCAGCATAATCTATTTTTGAATAACCAACGCTGGCAGGTTATTTATCAATTAGAAATTACCTATCCGGAAATCACCGAGACATACCATATTGATTTCTCGAATTCAAAAATTAAAATAAAAGAAGGGCGCAATCCTTTAGCTAATTTATTTACCTATATTACCGCATCTAGTTTGTACAATTTGATTAATAAAAAAATAGATTGGGATTATCTTTACTGTAGTGGGGAATATCGTAATTTTCATAAAGTCTATTCTCTAGCTAAGTTAGGTATTTTAACTCCAGCAGAAGATACCTTATTAGATCCAATTTCCATAAAATACTCTTCTGAATATGTCGCCGGAGAACATATAAAAACAGAACTATCAAAAATTATGGAAACTCACGATATATCTATACCCAATAATTCAAACATAGAAGAAAAATCTAGTACCATGTTGAATTTAGGTAATATATTAATAAAAATGAAAAAAAATCAAAAAGAGTCAACTATATCTTAATTTATCTACTTTCCGTGAGTTTTGTTTAGCTAATACATATTTTATCTTGCTGTATTCTACTTATAGCTTGATGAATCTTAGCTGCAATATCGTCTGAAGCTAATTCTTCCAATGTTAGCTGGCAAAGAGCAGCTAACATTATTGCACCATCTATTTTATTAACTTGCTCTGTTTCAAAACTTTTCAGATTTCGCGATGCATTGTAAACGAGTTTTTGTAATATCTCAAAACTTGTTTCAGATAAATTATTACGATAATTCTCTAATCTGCCACCTTGACGATAGTTGGGGAATGATTCCAAACCCATAAAATTCAAAAACCAATCATCTCGATAGTTACCAGCCGCCGAAACAATTCCTCGATAGTCAGCAATGAATTCATCTAACAAATTATTTCGCATCGAACCAAATAAACGTTTAGTCAGATAATGGGTACATTCATGTTCCAAACGAATAGTTAATGAAAGATTTTGCCATTCCGTTGCGGATAAACCTAGCTTTTCTGCTGAAACATTACTGTAACAGCTTTGGCTTAATATAATAAATCTATCTTGATAAAGCTGTTTGCGAGGAATGAGCTGACGAAACTCAATATTCCAATCAGTTTCTGTACTATTGGGGTTATTCGCTTGCCATTCTTGCCGATATTGATGAATTCTATCCCAATTATTAAAGCCACCTACCATACAAGCTCCCATCGAAGCAGGGATATCTTTGGGTTCGTTACGCATTGTTAATGCTTGCACTAAAGAGACGAAATCCAAACGGTTATCTGTAATGATTACAGGTATCTCTCCAGCTATACTCGGGTGTATTCTTAGCTGTAATTTTTCTGGTGCCCGCAATAACAAACCAGGATTTTTATCAATGCAATCAGCCACTATACCTTTACGAGTTGCAGCTTGATAAGCAGATGTTTGAGAGATTCCTGGCGATATCGGGAAACGCAACTGCACGAGCTTTTCTTTTAAAGTTTGAAAAACACCTTTACTTGTTGCTTCCGAGGCATAACTTTTCCAAGTATTGACATGAGCTTCGGATGCAAGTGGAAAATTAATTGCTTTAGACAAACAAGAATAATCAAAAACATTTTTGTTATAAGCTAATAGTTCTGCAACTTCTACACTATTAGCTCCATAACTGACAAGTATGTTAGCTCTTAAGTCTTGTAATTCCATACATTTATATTAGTAAAAAAAATAATAATTTTGAGTATTTTCAAGCTAGTTGAGACTATACTTTAAGCAGGTGTAGCTTGCCCTTCCGAACGAATTAAATTAGCATAATAACCTTCCATTGCCCATAATTCTTCATGAGTTCCACGCTGTACTATCTTGCCTTTATCCATAACAATAATTTCATCACAATCTCTAATAGTGCTTAAACGGTGAGCAACAATAATACAAGTACATCCCCGGCGGCGGATATTTTGGTCAATAATTTTTTCGGATTCACTATCTAAAGCGCTAGTAGCTTCATCCATGACTAAAATGGAAGGGTTGTTTACCAATGCACGAGCAATTTCTAACCTTTGTCTTTGTCCCCCACTTAAATTTGCTGCTCCTTCCATCAATTCACCATTATAAGCACCCGGTAATGCCATTACAACATCATTAATAGCGGCATCTAAACAAGCTTTAACTAACTGTCCATCAGGAATTGTTGCATCCCATAAAGTTAAATTTTCTCTTACCGTTCCTCCAAAAAGTAAAATATCTTGCTCAATATATGCCAATGAATTAGTAATAATTGAAAGAGGAATAGACGAACGGAGTTCTCCATCAAAAAGAATTTCTCCTTCCCAAGGCTGATAAAGACCTGTAATAATTTTTGCAACCGTGGATTTACCAGAACCACTACCACCAACTAAAGCAACTCTTTGTCCCGGTCTTAAACTTAAGTTAAAATCTTCAATTAAAGCTGCTTCTACACGACTATAGCCAAAAGATATATTTTTTAATTCTACTTGACCTTTGAGGCGATATGTAGTTTGCGGTCTCAGTTGTCTTGGTTCTGATGAAGTAACATTCTGTAATTGAGAATCTATTGGATTATCTAAAACGTCGTCAAGACGGTTAATATCTCCTTCTAATTCCTGCAAATCTCCTGCAAAAGAAACTAAAGTATTTACTGGTTCTTGGAAACTATCCATCAAGCTTTGAAATGCCACTAGCATCCCAATACTAATATAACCATCCATTACTCTAAAACCTCCAATAACTAATATCAACATTGAAGTTAAAGAAGTTAATAATGGAGGTAAAATTCCTAAAGTTTGATTGGAAACTGCTAACTCTTGTTGTGAATTAATACCCTTAGCATAGTAACCAGCCCATCGAGCAAAGAAATCTGATTCTAATGCTCCTGCTTTAATAGTTTCCATGCCTTGCAATCCGGCAATTTCTGTACCTGCTACTTTACCCAAATCTTGAGCTAATTTCATATTCGCGTCTACGCGCTGACGAGATACCAATTGCAAAGTAAAAATATTAACAGCAGCAAAAAATATGCCGATTAAAGTTAAAATCCAGTCATAAGAAAACATAACAATGGCATAAAAAACTAGCATGACTGTATCGATAGCAGTACTTGCTAATCTCCCAGAAAGAACATCCGCTACTTTCTCATTTAAACTAACTCTATTGCTAATTTCACCTGCAAATCGTTGAGCATAGAAACTTGATGGCAATCTTAAAATATGCCAAAAGAAACGACTCGTCATACCTACAGATAATTTAATTTTTAGCTGACGCAAATAGCGTTTTTGTAAAAAAGTTAAAGCAACCTGAAGAATCCCTGCAAGTCCCATAGCAATCAGTAACGGTCGTAACCAATCCGACCTTTGTTCTATGATGATACTGTCTACAAAAATTTGATTGAAAACAGGTATTGCTAATCCAGGAATTACAAGTAAAAATCCGGCAATTACACAGTATATAAGTGCAGCAACTGAACTTTTTAATCTATCAATTAGAGAAAATACTAAATTTGGCTTTCGTCCTCCTTTTTTAAATTCTTCACCTGGTTCAAAAACTAAAACTACGCCAGTATAAGCCTCATCAAATTCTTGTAAAGATACATTTCGGGGACCTGTTGCTGGATCGTTTAAGTAAACTCGTTTGTTAACAAAACCTTCTACTACTAAAAAATGGTTAAAGTTCCAAAAAACAATGTATGGTGGCTTAATCTCTAATAAGCTATCAAGTTCTCTTTTATAACCTTTAGCTTTCATCCCATATCGTCTGGCAGCTTTAAGAACATTAGAAGCTTTACTACCATCGCGGGATACCCCACACTCTTGTCGTAATTCCGGCAATGGCACAATGCGACGATAATAACCGAGGATTATTCCTAAAGCTGCCGCACCACATTCTACCGCTTCCATTTGTAGCAATGTAGGAGTTTTGAATCGCTTTTTTGCAAGATTTGGTTTGGCTTCAGTTTTGGTCATAGAATTTGAGATTTGTGTTGGGAAAATTATTTGTCAAAAAAAGCTAAATTAATGCAGAGTTTTTGTAGAAAATTATTGGCAGAAGTCCTAGATAACAGATTTTTTATAAAACTTTGATATTTACAGTAATTATTTCAAACCAGTCCAATCTCTTAATATTGGTAATACAAAAGTTATTGGTGCCCGTTGTTCAATTTTGACACGAGTATTAGTAGTAGTTCCTTGTGAAATTGTTAATTTCGGTCCTTTAGAAGATGACCAACGATAACCGCTAAAAGTTGAATCATCAGTTTGCAACTCTGCTAAAATAGCAATTCTTGGTTCACCAGCAGTCAACTTATTTACTAATTCTTGATTTCCTAATTCTAAGGCTGCTCCTTGTGGAGTAATTGGAAAAGGAGAAACTGAAACAATTTTACCGATGATACCTCCAAATCTTTCTCTTTTGACCATATCAGGAGTAACTTGAATTTCCATTCCTGGCTGTATTTTTTTTCCATCTTTTACAGGAAAATAAGTCACAGCGAGCATTTTTCCCGTCGCACCATTATTATTAATGCTAGCAATAGTAGTTCCCGGATTAATAACTTGTCCGGCAGTCGCAGTTATTTCTAAAATACATCCAGAACGTGCGCTCACAATTGTACTGTTGTCGGCAACTTTTTGTTCTAATTGAGCAATTGCTCGCTCAACTTCCTTTATTTGATTGAGTTTACTATTTCTTGTTTCCAAATTTTCTTGATCTAAACGTTTGGTTTTAGTTTCAATTTGTTGTAACTGAGTTTCCAGTTGAGAAATAGTATTTAAGTTGTTAAGATATCTCTGTTCTATTTGTGTTTGTTTAACTTTTAATCCTTTAAGTTGAACTTGAATTTCGCTAATGCTATTGAGGTTAGATAAATACTGCTGTTGCGATTGAGTTTCTCTCAAGTCTAGCTGTTTTAATTCTGCTTGTAAAACCGCAACTTGCTGTTGCGCTTCACGGAATTGCTGTTCTACTTGTAATACTGTATCGGCTGCAATCGCTCCCTCTTTTAACAACTGTCGTCGTTTTGTCAATCTTTCTTGCTGTATAGGAATTAAAGCTCGTGCATCCTCTAATCGTTTTTGTAGGCTAATTCGCTGCTGTTTAATCGCATTAGATGACTTAGTTTTCAGAGATGGTGTCACAGCTTCTTGTCTTTGCAATCGCTGTTGTAAACTTTGACGTTGTTGAGAAATAGATACTAAATCTTGATTTTTAAGTATCGGTGAAAGTTCTCGCGCTACTTTCAAACGTTGTAGTAAACTATCTCTTTCTGAAACTAATACTTCTTTTTCTAATTTAGTACGTTGACGTTGTAGCGCGAAGCTATCGGTTTGTTGCGTTAACAATTGCGCTCGTTTGGTGCGTTGTTGTTCTAGTTGTTGCTTTAGTTCTTTGGGATCGATTGTTGCTAAGATTTGACCTTTCTCGACACATTCACCATTACGTATGTCAACTGATGTTAATTGTCCTGCAATCTGAGATTGAAGCTGTACTACTTGTCTTGGATTAATCAGGACTCCGGGAGCGTTTTCTGTAATCGGAATGCGTCCAAAAACACTCCAAACCAAAGCCGAAAACACAAAAACACCTAAAGTACCTAGCGGTAGCCAATCTCTAGGATTTACTACCTGCATTAGTTGATCCAAACGTTCTGGAGAAGATAGTCTCTCTAAAGATTCCTTTCTAAATAGTTTTTCATGTTCCATGGAACAAATACCTATGTAAAGATACTGACTTATTATGTAGTTTTTAATCTGAATATATTATTCCCGTTTGAGCAATAAAAATTACAATAGGTATTTGAATTTGAAGCTGTTTTATTTTCTTACATAAAATAAAAAATCCTCTACGGATAACTGATCGTTAACAGCTTATGTTCAGCTCGTAAAAAGAGCCATTTTGAATTTAAACCTTAATAACTGAGAGTTTGAGATTAACTTTGGGAATATTAGATATAGGAGGTAGTGCGATTGAAGCAATACCTGCTAACCATCAAACTACAAACACAAACGGGCAAATAATATTAATTTAGAAGAGCTTTGCCAATGACTTGGATTAAAAAAAAATTATATCTGGCTGCAATTCCCCTATCGATTGGGATATCTATAGCTGCGGCTGTTTCAGTAAGAGCGAATGCTCCGAATGTATTTGCAGCTACGCCAAAGAATCGTACATTAATTAGCCAGAGCTTTACCCCACCAAATCGAGAAGGAAAAAGTCCTGTGACTGCTGGAGCGGCAACTCGCGGTGGTTGTGACACAAAACAGAACCTTGTAACTCCTTTAATGCCTAAAGAGAAATTAGGATTAACTTTTGACGAAAGACCTACATTTTACTGGCATACATCTAAATCCAATGCCGAAACAGCTGAATTTTTGTTATTGGATGACAATGATGATTTAGTTTACGAGGCTAATGTAAATCTTCCCAAAAAACCAGGAATATTTGCATTTACCCTTCCTCCGGAAGCTCCGGGTTTAAAGACTAATAAGCAGTATCACTGGTATCTTTCGGTTAACTGTAGCTCTGAAGAAACAGATGATATTGTAACAGTTGAAGGTTGGGTTGAAAGAACTAAACCTAATTTAGCTACCTGGATAAAGTTAAATAAATCAACACCAAAATATCGTTCTAAAATTTATGCAGATGCTAGTATTTGGCACGAAGCTATTACTAATGTAGCTCAACAACGCTGTATTGCTCCTTATGATTCTACTATGGTGCTTTATTGGAATCAATTATTAACTTCAGTCGGTTTAAAAGAGCTAGTTTCAGAATCTATAACCAATGTATGCGAAGTTAAAAATGATGATAATAAATAAAAAAATCTAATCATTTTTTCATCGCCTTCATTTTACAATAAAATACTTTAAATACTAGTTTCTATAATTGCTCTCTCGACTTTTAAGTCGAGAGAGTTCTAAATCAATATTTCAAAAAGTGATTTGAAACGATATAAATTCCTATTTTTAAGATAATATTTACGACATTTTAATTCTAAGCAATATACTAAATTATTGAAATACAGAAAAACTATAAAACTAATCTAATGCCAAGCATTAATAAATACTGATGACAAAACTACTATTTTTAGGTTCTGGTTGTGCTTTCACTGTTGGTACGGATAACTATCAATCAAATATGCTTTTGATTACCGATACTGGAAAAAAATTCTTAATTGATTGTGGTTCAGATATCAGATATTCTTTGTATCGGCAAGGCTTTTCCTATCTTGATATTACCGATATTTATATTAGTCATATTCATGCAGATCATGTTGGTGGGCTTGAATATATTGGTTTCAGTTCTAAATTCGATCCACGATGCCAAAAGCCAAGGCTGTATACAGATAAAGAAATAATGCATAACCTCTGGAATAACTCACTATCTGGGGGAATGAAATATATAGAAAATGAAATAGTTACCTTGGAAGATTTTTTTAAGCCTATAGAAATAGATGAAGATAAAGCTTTTTACTGGGAAAACATAAAATTTAACTCAATTAAAGTCATTCATGTAAATTCTGCTTCTGTTGTAACACCTAGCTACGGTTTATTCTTTGAAATCAATGGGATAAAAGTATTCCTAACAACAGATACACAAATGCACTGGAATTCTTTGGGAAAACTTTACCAACAAGCAGATATTATTTTTCAAGATTGCGAAACTGCAAAATTTCCTAGCGGAGTTCATGCCCATTACCAAGAATTATTAGATTTACCATTATCTATAAAAAATAAAATGTGGCTTTATCACTATCAACCAGGTAAACTGCCGGATGCCAAAAAGGATGGTTTTTGTGGCTTTGTACAAAGAGGGCAAGAATTCGATTTCTCATCATCAATATTCGCAGAAAATAACTTTACAGCGATTAATTCAACTTTTGTTTAGCTGCAATTAACTGATACGTATAGCAAAAACTAGCCGCAATTAATAAATAATATTACAACTTTAATTCATCAATACTGATAGCATCTACCAAAATATTTGTAGTTTTCATGAGATATTACTATTTGAAATTAAAAAAGATTTTAACAAATAAAATTATATTTATTTGGATTAGAGGATTATTAGCTTTTTTAGTTACTATTACCATATTTAATAAAAGTTTTTATTCAAATTCATTTTTATCGAGTGCGGTTGCATCTACCCCGAAATATAGTTATCCACTCAAATACGCTAAATACGATCAAATATTGCCAGCATCAAACAATGTTGCTGATTCCCCAGACTTATTAACGCAAGCCGGTAAACAATATTATCAAAACCAGCAATTTAATCAGGCAATTGCAAAATGGCAGCAGGCACGTGAAATACTGATTTCCAAAGGTGATAATATAAATGAAGCGATAGTACTCGGTAACTTAGCACAAGCATACCAAAAATTGGGGAAAATCACCGCAGCAAAAAAGGCGATCGCTAAAAGTATTGAGATTTTATCTTCCTCTCAAAAACACCATCAAAACCTCTTAGCTAATACTTTTAATATTCAAGGAAGTTTGCTGTTATCGGAAGGTAAATCTGAAGATGCATTAGTTGTTTGGCAGCGTGCAAAAAATATATACGAAACAGTTGGAGATAAAAACGGACTAACTCGCTGTTTGCTCAATCAAACTCAAGCTTACACTCAATTAGGAATGCATACTCGGGCGCTAAATACTTTAGAAGAAGTTAATCAAAACCTAAAACTGCAACCCGATTCTGCTTTGAAAATTGTCAGTTTGCTCCAGAAAGGAGATGCTTTGAGACTGACAGGAAACCTTAAAGATTCCCAAAAAGCACTACAGCAAAGTTTGGCTATTGCTCAAAAACTTAATTCCGATACCAATATAGACAAAATTCTTTTGGCTTTGGGTAACACCTCTCGTTTTGAAAAAAAAACTGAAGAGGCTTTGAAATATTACCAGCAAGCCATCGATAAATCAAAATCCCCTGGGATAAAACTTCAAGCACGGTTGAATAAATTACGGCTTTTAATAGATACTCAAAAATTATCAAAAGCTAGAGCATTAGCAACGCAAATACAGCCTCAATTGGCAAGCATACCACCTAGTAGAACATCGGTATATGCATTAGTTAACTATGTGCAAAGTATTGAGCATTTAGAAGGTAACAAAATATTCAACAATCAAAAAGCTGCAAATAAGATAGCGGCAAAAGTTGCTAAAGCGGCTCGGCAAGCCGAAATTTTAGGAGACGATAGAGCGCAGTCTTATGCACTTGGTTACTTAGGACATATTTACGAACAGACTCAGCAGTTAAAACCAGCAAAAACATTAACCCAAAAAGCATTAATTCTGGCACAAACAAGTAATGCTCCCGACATTACTTATCGCTGGCAATGGCAATTAGGAAGATTACTAAAAAAGCAAAGTAACTTTGTAGAAGCAATTTCGGCATATGACGGTGCTGTTGCAACTCTTGATTCAATCCGCAATGAATTGGTTGCCAGCAATCTCGATATTCAGTTTTCGTTTCGTGAAAGCGTTGAACCCGTTTATCGAGAATTTGTAAGTTTATTGTTAACTCCAGAAATGGGAGAGACAAGTCAAGAAAAGCTTAAAAAAGCACGTCAGGTAATTGAATCTCTACAAATCGCAGAACTAGATAACTTCTTTCACGAGCCTTGTTTGAAAGCAAATCCGACTCAAGTCGATAGAATTGATACCCAAGCGGCAGTTATTTATCCAATTATTTTAGAAAACCGTCTGGAAACAATTGTTTCTTTACCAAAGCAACCTTTACGACACTATACTACAGCTATTTCCGAAAACGAACTAGAAAAAATGGTGCAGAAAATGCGCCGAGCTATCAGACGTAATTTCCTTAAAAAACAACACTTTGCTATCTGTCAGGAAATCTATAATCTACTTGTTAAACCATTAGAAACAGATTTAGCAGCTTCGGAGATTAAAACTTTAACATTTGTTCTAGATGGTTCCTTGAAAAATGTGCCATTAGCCGCTTTACATGATGGAAAGCAATATTTAATAGAAAAATACAATCTTGCTTTAGCTCCAGGAATGCAGTTGCTAGATCCTCAACCTTTAGCGAGTCAAAAAATGCAAGTTTTAATTGGAGCTTTAAGCGAAGGAAGACAAGGTTTTGTACCCTTACCTGGTGTTAAAAATGAAGTCGAAAAGATTAATACTGAAATTTCAACTCAAGTACTTCTCAATCAAAAGTTTACTAGCAAAGCTTTACAAAAACAAATTAGTCAAACTCCTTTTCCTATCATACATTTAGCAACTCACGGCGAATTTAGTTCTGAAGCTGAAGACACATTTGTTCTGACTTGGGATAACCGTTTAAATGTAAAAGAGTTAGGCAATATTCTTCAAAGTAGAGAACAGAGTACTACTAATCCCATCGAATTATTAGTTCTTAGTGCTTGTAAAACAGCTAGCGGTGACAAACGCGCTCCTTTGGGCTTAGCTGGTGTAGCCGTGCGCTCTGGGGCACGCAGCACCATAGCCAGTTTATGGGCAGTGGATGATGAAGCAACTTCTCAGATGATGGTAGATTTTTACGAACAAATAAATCAGCCTGGAGTCACTAAGGCAGAAGCTTTACGTAAGGCTCAAATCAAAACTTTGCAACAATCTAAGTTTAGACACCCCTATTACTGGGCAGCTTTTGTTTTAGTTGGTAATTGGCTGTAATAATTGGTAATTGGTAATTGGTATTACTCTTTCAACGTTTGCTATTAACAGTATTTTTATTTCGGCTAATTAGTATGGTTATTGGTAATCGCTTAATAATCATGCAGAAACAAGAAACTTTAGCTCAATTAATTTGTCGTACTGTATTAGAGTTTGAACAGCGCCAAGCAAAAGTAGCACAAGATAAACTTCGAGAGTATACATCAGAATCGGCTATTATTGATACATCTAACCAAACTATATCTAAACAAAAATCAGCATAATTTATAGTTTTATTAGTAACTTGTAGAATCAAGATTGTAATTTTAAATTCAATATATAGTTATTGTTTAATACGTACAGAAAATGTGATAATTCAGAAACCCGGTTTTTTTCAAAAAGCTGGGTTTTTACTATATATATAAATCCGCTTCGAGTATTGAACAAATCCAATTACCCATTACCAATTACCAATTACCAATTTTCGACTTGATAGTCAGCACATTAGAGAACGCATGTGCCACAAGTCTTTTCCAGGCCAGAAGGTTGCACCTTTACCGTAATCGCTGCTAGCACATAACTCTTCGATTTCAGCTTTAAACTCATTGTTAGAGTTGTGAACTAAAACGTGAACGGGTTCAGCACCTAGTTCCATCAAGAAGCTGGTCATACCGTATACTAAATCGGGGTCGCCGTAGATAGCAAAGCGCTTACCGTGTAACCAAGCGTGAGAGTCAGTCATAGCGTCAACTGCACGTCCGCGCTCTTCTTCTAACTCTTGAGGAATGGGCTTACCAGTTAATTCACTGAGCTTCATTAAGAACTCATCAGTTCCGCGAATACCCCAAGGGCGAACAACTGATGTGGGTTGCTTCCACTCTTTCTCCATATATTCGCGAGTCTTAGGAGTAGAATGTGCTTGCAAGCAAAGTGTAGCTTCAGCGTTGCAAGAATCAGCAGCATCTTCCAATTTTGTACCCTTGGGATACATGTTGAATTTACCATCGTTAGGTGCATCAACGTAATCGGAGTTGTCAGCTAATAAGGTATAGTCAATACCCATTAACTTAGCAATACGCTTAACTTCGCGTAAGTTGCCAACATAGGTATCAAAACCAGGGATGATATTGATTTTACCGTTGGTTTTATCTTTCTTCTTACCTTGAGTAAGGTTTAAAAGAATACCCTTCATCATATTATCGTAGCCGGTAATATGAGAACCTACGAAGCTAGGGGTGTGAGCGAAAGGTACGGGTAAATCTTCAGGAATGCCACCTTCATTTTTAGCATTACCGATAAATGAACCCAAGTCATCACCGATTACCTCAGCCATACAGGTTGTGGAAACGGCAATCATTTTAGGACTGTATAGCTTGTAAGCATTAGTCAAGCCATCAATCATATTCTTCAAACCACCGAATACCGCAGCATCTTCAGTCATTGAAGAAGAAACAGCAGAGAAAGGCTCTTTAAAGTGGCGGGTTAAGTGGGTACGGAAGTAAGCAACGCATCCCTGAGAACCTTGCACGAAGGGAAGAGTTCCTTCAAAACCAGCAGCAGCGTAAATAGCTCCTAAAGGCTGACAACCTTTTGCTGGGTTAACGGTTAAAGCTTCGCGAGCGAAGTTCTTTTCACGATATTCCCAAGACTTAGTCCATTCTGCAACTTTCTTAACTTCTTCGGGATCGTGTCCGCCTTCAAACTTTTTCTTGCCTTCAAAAAGCTCTTGATATTCCGGGTTGTGGAATAAATCAACGTGGTCTTTAATTTTATCGGGATTCTGTGGCATGTGTGTTCTCCAAGCTTGCTGGTAAATAAAAATTAGTGGTTTGATTGGGAGGATAGGGAATAAGAACAGATTTTCCTATTCCCTTTAATCCTTAATCCCTAAGCAGCTGCTTTAGCTTTTGCAGCTTGAGTAGTAGCAGCAGGTTCTTCATTCTTCCAAGGGGTTCCAATCAATTTCCAGGAAGGATTGTTGATTGCTAAATCCATGTCACGAGCGAAGATAGCGAAGCCATCATAACCGTGATAAGGTCCGGAGTAATCCTTTTTATGGTTTTTTCTTAATCTATATAAAAATGTTTTTTACAACCAATGTTAATCTGAAACATTGTTTGTTTATGACATATTTAATTATGACTTTGTTGTAGTCTAAATCTAACTATGCATCTCCAGGATTAAAGTTTTAATAAATATTGATTTTAGAGTTGAATGTTAATATATGAAAGAAAATATATTGTCAGAACTAGATAAAGTAAATCAGCGCTTAAAAGCAGCAAAGACAAAGGTAACAATTAGGGAATCAAATGGCAGTTTACAGTTACGCGCTACTTTGCCAATTAAACCAGGAGATAAAAATACGAGAGGAACGGGAAGAAAACAATATAATATCAGTTTAAATATTCCAGCGAATTTAGATGGTTTAAAAACAGCCGAAGAAGAAGCGCAGGAATTAGGAAAATTAATTGCTAGAAAAAGCTTTGCATGGAACGATAAATATTTGGGTAAAGAAGTCTCAAAAGATTTTAAAACTATAGGTGAACTATTAGAAAAATTTGAAGCAGAATATTTTAAAACCCATAAACGCACTACAAAAAGCGAACACACTTTTTATTATTATTTTACTCGAACCAAGCGATATACTAATTCTCAAGATTTAGCGATCGCCGAAAATCTGATCGACTCAATTGAAAAAATCGATAAAGAATGGGCAAGATATAATGCAGCCAGAGCGATATCTGCATTTTGCCAAACTTTTAAAATTGATATCGATTTATCAAAATATTCCAAAATGCCGGAACATAATTCCCGCAAGATACCCACCGACGCAGAGATATCTACAGGCTTTACCAAATTTGCAGATTATCTTGATACAAGAGGAAAACAAGTAAATAAAAATGTCAAAGATAGCTGGCAACTATGGCGCTGGATATACGGAATGCTTTCAGTGTATGGTTTGCGTCCGCGAGAACTATTTATCAATCCCAATATTGAATGGTGGTTGAGCGAACAAAATGCAGATATGACATGGAAGGTAGACAGAAATTGCAAGACGGGAGAAAGAGAAGCATTACCTTTATATAAGCAGTGGATTACAGATTTTGATTTAAGAAACCCTAAATATGCAAAAATGCTCGTAGATGCAGTTAACAAAAAAGATAAAAATAATCACGCACAGATAACTGCATTAACCCAAAGAGTTAGTTGGTGGTTTCGCAAAATCGCATTAGACTTTAAACCCTACGATTTACGTCATGCTTGGGCTATTCGAGCGCATATTCTTGGGGTTCCCATCAAAGCAGCAGCAGACAATTTAGGTCATAGCGTCCAGGTGCATACTCAAACTTATCAGCGTTGGTTTTCCTTGGATATGCGAAAGTTAGCAATTGATAATGCTTTGAATAAGAAGAGTGAAGTTGAGGTGATTAAGGAAGATAATCAAAGATTGAGATTAGAGGTTGAGAAGTTGAGGATGGAGAAAGTTTATAGTAATTTGTAG

Protein sequences of DBSCAN-SWA_5

>NC_019678|7907518:7956560|7924061_7925252_-|WP_015122156.1|DBSCAN-SWA
MNTVIFDSNIVGKQAVNSDAKLVSSEAVELLSRLTKRKLHHKQVTPELMFLASLITMTFGVMFADGVVTESETQLLEKTIDQLIPSKGDVTVLIQQLIDGNRENAVYQNPSEWLKLTASLSQQERTLLMNFSYEMSAVDGHIDDSEKEYLKAAGNALKVSTKYTEVLEAWYSGKKVEQSAWNELQDFISPPNFSHLNLRFVSLDAVELLSSLTDKKFVKTDINDTLIFLTVLLIITWGVIEADGMQEEAEKKLLAKTIKRLIPHKNRQMREIMETLVNKVPQTGIYQHPQEWLKLAKSLSESEKILMMSFCYEMSAVDGEISIEEKKYLQKAADFLDIEHKYTAVLESGFSGDGIDDTKTFNQLQSLIHPDKFQNMDEVFVEAAKYIIDTLEVISF
>NC_019678|7907518:7956560|7944178_7946389_-|WP_015122171.1|bacteriocin|DBSCAN-SWA
MTKTEAKPNLAKKRFKTPTLLQMEAVECGAAALGIILGYYRRIVPLPELRQECGVSRDGSKASNVLKAARRYGMKAKGYKRELDSLLEIKPPYIVFWNFNHFLVVEGFVNKRVYLNDPATGPRNVSLQEFDEAYTGVVLVFEPGEEFKKGGRKPNLVFSLIDRLKSSVAALIYCVIAGFLLVIPGLAIPVFNQIFVDSIIIEQRSDWLRPLLIAMGLAGILQVALTFLQKRYLRQLKIKLSVGMTSRFFWHILRLPSSFYAQRFAGEISNRVSLNEKVADVLSGRLASTAIDTVMLVFYAIVMFSYDWILTLIGIFFAAVNIFTLQLVSRQRVDANMKLAQDLGKVAGTEIAGLQGMETIKAGALESDFFARWAGYYAKGINSQQELAVSNQTLGILPPLLTSLTSMLILVIGGFRVMDGYISIGMLVAFQSLMDSFQEPVNTLVSFAGDLQELEGDINRLDDVLDNPIDSQLQNVTSSEPRQLRPQTTYRLKGQVELKNISFGYSRVEAALIEDFNLSLRPGQRVALVGGSGSGKSTVAKIITGLYQPWEGEILFDGELRSSIPLSIITNSLAYIEQDILLFGGTVRENLTLWDATIPDGQLVKACLDAAINDVVMALPGAYNGELMEGAANLSGGQRQRLEIARALVNNPSILVMDEATSALDSESEKIIDQNIRRRGCTCIIVAHRLSTIRDCDEIIVMDKGKIVQRGTHEELWAMEGYYANLIRSEGQATPA
>NC_019678|7907518:7956560|7950415_7953079_+|WP_015122175.1|DBSCAN-SWA
MRYYYLKLKKILTNKIIFIWIRGLLAFLVTITIFNKSFYSNSFLSSAVASTPKYSYPLKYAKYDQILPASNNVADSPDLLTQAGKQYYQNQQFNQAIAKWQQAREILISKGDNINEAIVLGNLAQAYQKLGKITAAKKAIAKSIEILSSSQKHHQNLLANTFNIQGSLLLSEGKSEDALVVWQRAKNIYETVGDKNGLTRCLLNQTQAYTQLGMHTRALNTLEEVNQNLKLQPDSALKIVSLLQKGDALRLTGNLKDSQKALQQSLAIAQKLNSDTNIDKILLALGNTSRFEKKTEEALKYYQQAIDKSKSPGIKLQARLNKLRLLIDTQKLSKARALATQIQPQLASIPPSRTSVYALVNYVQSIEHLEGNKIFNNQKAANKIAAKVAKAARQAEILGDDRAQSYALGYLGHIYEQTQQLKPAKTLTQKALILAQTSNAPDITYRWQWQLGRLLKKQSNFVEAISAYDGAVATLDSIRNELVASNLDIQFSFRESVEPVYREFVSLLLTPEMGETSQEKLKKARQVIESLQIAELDNFFHEPCLKANPTQVDRIDTQAAVIYPIILENRLETIVSLPKQPLRHYTTAISENELEKMVQKMRRAIRRNFLKKQHFAICQEIYNLLVKPLETDLAASEIKTLTFVLDGSLKNVPLAALHDGKQYLIEKYNLALAPGMQLLDPQPLASQKMQVLIGALSEGRQGFVPLPGVKNEVEKINTEISTQVLLNQKFTSKALQKQISQTPFPIIHLATHGEFSSEAEDTFVLTWDNRLNVKELGNILQSREQSTTNPIELLVLSACKTASGDKRAPLGLAGVAVRSGARSTIASLWAVDDEATSQMMVDFYEQINQPGVTKAEALRKAQIKTLQQSKFRHPYYWAAFVLVGNWL
>NC_019678|7907518:7956560|7922584_7924009_-|WP_044292536.1|DBSCAN-SWA
MRIFIEKILLELSQILEKPVLKIGETSISFASLLQLVFSFVVVIIFCRILYNLLKNKLLINFGIDEGNREALATIFTYIFGSLGFLIVLESTGFNLASLAVLAGGLGIGLGFGIQNITANFISGLTLLVERSIKVGDIIELWISEEFKTLQGRVKKITLRSTVIQTLDGSSLIIPNSELVQKPILNCTYNDSNVQICLSINIEYGNDPLIVTEILLDAAYMEPLVAKDNPPQVIFNGFANGYLDFDLRVWINQIQDKNHVRSILNYAIEYNLRRQGIYFVTNRYVNEKSFSLYSQYNKFETQQKKISLRTLLRQVIYFQNFNDLDLRKLLEIGYRQQIKESEILFKENDPGDAFYIILSGKVEVFVSKINKHLTTLGKAQFFGELALMLAIPRTATVKALEDTTLFVINNQGFEKLLKGNPELAEEIVNELAKHQEELTSRQQQLREMGLIDESEDDINPVVWVRKRLKKVFDL
>NC_019678|7907518:7956560|7955282_7956560_+|WP_015122178.1|integrase|DBSCAN-SWA
MKENILSELDKVNQRLKAAKTKVTIRESNGSLQLRATLPIKPGDKNTRGTGRKQYNISLNIPANLDGLKTAEEEAQELGKLIARKSFAWNDKYLGKEVSKDFKTIGELLEKFEAEYFKTHKRTTKSEHTFYYYFTRTKRYTNSQDLAIAENLIDSIEKIDKEWARYNAARAISAFCQTFKIDIDLSKYSKMPEHNSRKIPTDAEISTGFTKFADYLDTRGKQVNKNVKDSWQLWRWIYGMLSVYGLRPRELFINPNIEWWLSEQNADMTWKVDRNCKTGEREALPLYKQWITDFDLRNPKYAKMLVDAVNKKDKNNHAQITALTQRVSWWFRKIALDFKPYDLRHAWAIRAHILGVPIKAAADNLGHSVQVHTQTYQRWFSLDMRKLAIDNALNKKSEVEVIKEDNQRLRLEVEKLRMEKVYSNL
>NC_019678|7907518:7956560|7909735_7914205_-|WP_015122150.1|DBSCAN-SWA
MRHISIFSTLNSILPIIFSSVLFVNILEAQAQSVIPARDETGTVVNNNGNRFDITGGQFSQDGSNLFHSFQELGLSQNQIANFLSNPGIQNIFGRVIGGNPSVINGLIQVSGGNSNLFLMNPSGIVFGNDASLNVPGDFTATTANGIGFGNNWLNAFGKNDYAILTGKPISFAFTMSQPGAIINAGNLNVNNGNLSLLGGSVASTGNLEAASGNIIVSAVPGKNLLRLSQPGNLLSLEIEPISTAKNLPQPGNLTIASLPEMLTGGNSGVTKLVRNSNGEVELKGSGLTLNQGDATVKTLNAENALLSADGNLTFFESQLQTTENLTLLAKDTVRVRDSATNPFIAIAGGDFYLRGDRQIDILALNHLDKTPFVSGGDLSLVSNGIISGDAHFASGGKFSILNLQGDGGKFISLYDPIISSEEDVTFGSYVGAALKVESKGSITVEGDIEITSLDSDICQSTCSADAQILASEAALILRAGVAELEEPTFNYPSGFNDVPFTVQGTATSPANVTVNGDIITSFDESVGRVGRVIISAPGNITTGNIFTEYSSEEFFVNDAFGGEVNLNAGGNISATEIDSSVDINAGDFVGGGNINLEAGGNIVVREGISSEATTFENVDQISAGDINIKAEGNVVIEDGINAKVFVGSANDISAGKINVDSGGDIFVSEIKSSVDVNGFITSPNNAFGGEVNLKAIGDIVNGSINSGVVLSATSDNGIAGNINLTADGNIYVADVEAFVELNGVSAQNAAAGNININSGQNILFGSVNSSNFEEEDSPVGRGGDVKIIADNGTVRGGLYVSAEDRIEEEENFVRALEIPEWFKLPEEIDIGEGELKLIELNFPNTIATVGEDSSGSVEIRHDGTRENVPFIVGDASLNGTAGAINTGTNIISPTTEFPNPGTENQGNINITFTNTPPDVTVNSALNITAENQPVTFKLADIGTQVIDVNNDITELKINDIAPQGTLKINGNEATAGDIITSEDSLEYIPNANNTGNINAFTIVASDKISVSTPTEIRVNISEQQPEINPETENYRQKLPKPPEFREPPLLKIDRTFNQSSRLEIDRMMGKVEDSFTNAFKNYLGKEIDPTLKGLVEARNILNSVEKATGIKPALVYAMFVPASLASDLELDSKLKNTKTNFKKDSDVLEILLVTGKGKPIRKQIRSATRGNLLKVARKFQREVSNPRKSTTKTYLKPSKQLYQWVIAPIEAELQTQGIQNLSFIVDVGLRSIPLAALNDGNSFLIEKYSMGLMPSLSLANTNYADIKQAEVLAMGASEFTEQNPLPAVPLEINTISKQWKGRAFLNNSFTLENLKSQRSNQPFGIIHLATHAEFRPGKLKNSYIQLSNQKLRLDEIRKLGWNNPPVELLTLSACRTALGDKEAELGFAGLAVQAGVKSALGSLWYVSDEGTLGLMTQFYQQLKQAPIKAEALRQTQIAMIKGQMSLEKGILQLPQSKNIIPIPSLAGRSRKFTHPYYWSSFTLIGSPW
>NC_019678|7907518:7956560|7938342_7939443_+|WP_015122167.1|DBSCAN-SWA
MIVTNSLTDYLSLLNSFVPRELIAESEWRKFNHIGNILPSALTTFFGFESRLGIPEAHGDFLICADAHEAGRRVLAANSYDIDLPTELLHHPVWMNIRKFSTNWESEASPLYDKITNVWLEFDVGNETKDLPVPSCFFGPKNLYNTPAVDSEHPYKWIWENALPLLLGRSFPKSVENNIVKCFAALPENAYVFQVGLMLAREWDGVRLCIRNISPEKIIDYLKSLDWQGDLNNLQLQLNNISPLVDRIDLDIDVTEGLGDKIGLECYLNKQPQFEKRWSLFLDNLLLKGLCFPKKQQALLTYPGYIQEKMNPSLWPLSLRKISKILGDSYEWVIFKGIHHIKLNYCDAEIKEAKAYLYVSRSLIRG
>NC_019678|7907518:7956560|7908001_7909414_+|WP_015117597.1|transposase|DBSCAN-SWA
MYKTVPIKAKFTDEEKAFWVDQCEHSNSLYNSAIYLARQNHYAMLLERKANTTYWCGDELRSGWKTYRLETNYYHLDKQLKTCIHYFSLAAQAAQQTLKLVGESITSYNKLVDKYYLGDGSRPSIPKYRKSGGLFAVTFPKQALACHNGYIYPSISKATKPELITSIKLILPEFISFDWIKEVIIRPSRGEFWVDWVIDDGKQPIINNKSLNYNHAISIDHGVKFWLSAVTTLGKSFIVESPQLKTALHKYRNQVQQHKKNKPSRYWDNYLDRITAKRNLQVRDAVNKAARFIINKCLKDGIGNLVIGWNEGNKTNINIGRNNNYEVVSMPTKRLIERLRQLCEEYGIRFHITTEEYTSKASFIDNDELHQYGAKPIEWKPSGKRISRDVYRTKDGLLIHADLNAASNILRKVADQIFINSGIAKLAFEIIKRGALTHPKRYDIFSNLKRSYRKQTMSRSMSLDYGVTTA
>NC_019678|7907518:7956560|7936146_7937616_+|WP_015122165.1|DBSCAN-SWA
MNNAISFSQGSQIRPFNVNDRVCLAIQPFIQEVLNRFVECQNLGESIKASVENHQEIVEQAFEIDNHKIEESFTLKQEFLFPEENPLLFISYDNPSFLPFLNKKGVQSIKDESILPDIHQLLYSIGQSKFTYQQIKQQISEPMVDLLDKLIKSSVVKEKPAVDIGVPLNTPGVFRLQHASVLYRTKTTGILVDPHLHSNYGIPGLKSDINRAQLEGLVDGILISHPHYDHWHYPTLMMFAKETPIFVPKVPRASIMCEDMAGRLKSLGFTNVIAVDWYSEPIRIGDININVLPFYGEQALVPEFDKPKYPELRNWGNTYLIDTEFYKSWLLIDAGQEPNGSMIEVAEYVKNSFGSIDLLISNFQPLSYNSIGTNLSGWGIDIVANLLSNPQIFSVTNKPEGAYIALLGPKGVAEVCNIVNASYCFPYADSWAEAGKSGMHDEELIPQVQAELQKIGCSTKVIPWKIGDGYVTRNVTEWNLEAGNWYMNN
>NC_019678|7907518:7956560|7937680_7938301_+|WP_015122166.1|DBSCAN-SWA
MISSIQTQKKCYSQRKDAFSNEYLEFLKKDILNSPYLAASQLSDGFVETQGFSVVFKRSTIAEVEKKLPYFKPYLDTALKSSCNAFYLNPLILNSDTYVEPHVDCSISEYGMEMVMPNLVSVLYVQVPSDLKGGELVLQQSEEQVWQITPQINTLLYFLGWITHSVNRVESSHKRISLICEQYNLSESRLNKIPDFEIKSGKDSGK
>NC_019678|7907518:7956560|7933858_7934185_-|WP_083894164.1|DBSCAN-SWA
MSIEAVNQFLEKVAKDSNIQEELVQAMQAENDRQAVVELGAKHGFNFTGDELMNEIEKRQKAAADSGELSEEELEAVAGGATPTFTTIVPIVTATAPVVVTIAKKVKW
>NC_019678|7907518:7956560|7919764_7919941_+|WP_015122153.1|DBSCAN-SWA
MQAIKIKLSILVGVSMLLLMPSVATANNNSAEESINSQSSSLISSSSCGRGDRCRPPA
>NC_019678|7907518:7956560|7920291_7922532_+|WP_015122154.1|DBSCAN-SWA
MRDLHYILLALSVTFLLLPVSEVEAQLIPDNTLGKENSLVNPVNSVQRIDGGTIRGSNLFHSFQEFNIGSGKSAYFSNPGNIENILTRVTGKNSSLILGKLGVLGNANLFLINPNGIIFGENAQLDINGSFVGSTADNIKFADGREFNAVNPSANPILTINVPLGLQYKGNGGNIEVRGTATSNLKVPDKKSLALAGGNIKFDGGKLTAPAGGIDLFAVTNGEVSLVNSNGRINLKTPLGIEYGDIEFLNASNIDASGNSGGSIQVRGRNISLKGNSIISTNTDGDGFGKTLNITATELLKISASDLFADVQDNATGTGGDLVVNSKNLIVTDGSILSSSTFGLGNSGNLTIKTINLQVDNAGRIDVTTYDFGNGGNLTIETANLQVYDGAQITAIAFGKGNAGNMEIKANLVELVGFRQSSDIPLKSGLFANALQENGQGGNLNVTANRLVIRDGATINASNFLSFDPDNLLGRAGTGAAGNIDINSPFVLLENQGIITANVNAGDKGNINIQSQNLQLRKGSVISTNAKNSADGGNINIDTNTLVALENSDIAANSEGSFGGRVIINAKGILGTQFQQQLTPQSDITATSSLGASFSGVVDINTIAVDPNSGLIELPQTLTDSSQKIKAGCDATAGNNFVVSPRGGLPQSPDDLFNGSTIYTELNDVIPIQDIASDINDRNHQNYRNRLSSVENKHKNQNKNQIVEATGWVVDGKGDVVLVAKMPQHSQKSPKINSASCNDFSS
>NC_019678|7907518:7956560|7953554_7954847_-|WP_015122177.1|DBSCAN-SWA
MPQNPDKIKDHVDLFHNPEYQELFEGKKKFEGGHDPEEVKKVAEWTKSWEYREKNFAREALTVNPAKGCQPLGAIYAAAGFEGTLPFVQGSQGCVAYFRTHLTRHFKEPFSAVSSSMTEDAAVFGGLKNMIDGLTNAYKLYSPKMIAVSTTCMAEVIGDDLGSFIGNAKNEGGIPEDLPVPFAHTPSFVGSHITGYDNMMKGILLNLTQGKKKDKTNGKINIIPGFDTYVGNLREVKRIAKLMGIDYTLLADNSDYVDAPNDGKFNMYPKGTKLEDAADSCNAEATLCLQAHSTPKTREYMEKEWKQPTSVVRPWGIRGTDEFLMKLSELTGKPIPQELEEERGRAVDAMTDSHAWLHGKRFAIYGDPDLVYGMTSFLMELGAEPVHVLVHNSNNEFKAEIEELCASSDYGKGATFWPGKDLWHMRSLMC
>NC_019678|7907518:7956560|7915035_7917285_+|WP_015122151.1|DBSCAN-SWA
MWKILKNKVWQWSSVLIAAPSVTLLVMLVRLSGLLQMLELAAYDQLFILRNSEKQDERIVIVEIDEEAIRKLEYPIPDRKLAQILQKIKQHQPRAIGLDFYRDKPVGKGYDSLAKVFESTPNLVGVQKVAGSIDSATVNPPPILKELDRVGANDFPLDADGKIRRGFFYLADKDGNQIFSFSFKLAYLYLNAMNIYVGLAPPDNQLIQVGKVVFTPFGSNDGGYVRTPDGDYQVLLNYRGDIEKFQSVSVIDVLENRVPKDLMKNRIVLIGATASSLKDLFYTPYSANLFRNIRRMAGVTVHANAISQILDAELSDRPLIKTWNEEFEWLWTFSWSLVGAILIWLLRSSKRKILPLVSLVLAGFCLLSISYLTFLYGWWIPVIPPMLGLFGSAVGVTAFLAQSASKIRKTFGRYLNDEVVANLLESPEGLKLGGQRRNITIFTSDLRGFTATSERLPAEEVIKIINLYLGYMADVITEYQGTIDEFMGDGILVLFGAPTAREDDATRAIACAVAMQQAMEPVNQKIKEMGLPKLEMGIGINTGEVVVGNIGSEKRTKYGIVGKQVNLTYRIESYTVGGQIFISESTLKQVEPIVKIIGERQVKPKGVQQPITIYEVGGIAGDYNLYLKQEEELFVKLSQPIMFEYAVLDGKDISDTLQIAKLIQLSENAAEVCIKVNSDEVISIPQPLTNMKMNLLVSINGAEKSGDIYAKVLEKPAASKNSFYIRFTNKPPEVEAYLDSIYKSMKKDK
>NC_019678|7907518:7956560|7953180_7953342_+|WP_157229355.1|DBSCAN-SWA
MQKQETLAQLICRTVLEFEQRQAKVAQDKLREYTSESAIIDTSNQTISKQKSA
>NC_019678|7907518:7956560|7934308_7934623_-|WP_015122162.1|DBSCAN-SWA
MSIEAVNKFLDKVAQDSTIQEELAQAMQAENDRQAVVDLGAKHGFEFTGDELVTEIEKRQKAAAESGELSEEELEAVAGGAFPIIPLIGALAPIAIAAINKAKW
>NC_019678|7907518:7956560|7946518_7948132_-|WP_044291278.1|bacteriocin|DBSCAN-SWA
MCSMEHEKLFRKESLERLSSPERLDQLMQVVNPRDWLPLGTLGVFVFSALVWSVFGRIPITENAPGVLINPRQVVQLQSQIAGQLTSVDIRNGECVEKGQILATIDPKELKQQLEQQRTKRAQLLTQQTDSFALQRQRTKLEKEVLVSERDSLLQRLKVARELSPILKNQDLVSISQQRQSLQQRLQRQEAVTPSLKTKSSNAIKQQRISLQKRLEDARALIPIQQERLTKRRQLLKEGAIAADTVLQVEQQFREAQQQVAVLQAELKQLDLRETQSQQQYLSNLNSISEIQVQLKGLKVKQTQIEQRYLNNLNTISQLETQLQQIETKTKRLDQENLETRNSKLNQIKEVERAIAQLEQKVADNSTIVSARSGCILEITATAGQVINPGTTIASINNNGATGKMLAVTYFPVKDGKKIQPGMEIQVTPDMVKRERFGGIIGKIVSVSPFPITPQGAALELGNQELVNKLTAGEPRIAILAELQTDDSTFSGYRWSSSKGPKLTISQGTTTNTRVKIEQRAPITFVLPILRDWTGLK
>NC_019678|7907518:7956560|7935002_7935332_-|WP_015122163.1|DBSCAN-SWA
MSVEAVNQFLTKVAEDAQLQEELAKAMQSENDRQAVTELANNKGYDFTGDELMQEIEKRQQAAADAGELSEEELEAVAGGATPATTFFVAGGIAMTAGITGGVIAKAKW
>NC_019678|7907518:7956560|7931673_7932642_-|WP_015122159.1|DBSCAN-SWA
MALKHINYQPTMTEFLVNKKTFSKNPLLVMDIGARGGFEHHWQSYGEQVYKIGFEPDKEECDRLNQQPNRNSKFYAVALGEKREKRTFSFCQWGGSSGFYPGNKNFLKRFPHDNLEMMEVVKTLDIETVDLDSFVADNKIDEIDFIKLDVEGSELDVLKGAVSCLNESVLGLSIEVLFHESIRNQPTFSHIDLFLNSLGFRLFDLATYRHARKALPLPMISQLGNTKQGQVLWAQALYLRDAVNELETKESANKWNKLKILKLASLMEIFCLPDCAVELIQIAAEKNILTEDLELFLNYLTPPIQKEGNSEYISYQNYLKLF
>NC_019678|7907518:7956560|7948462_7949239_+|WP_015122173.1|DBSCAN-SWA
MTWIKKKLYLAAIPLSIGISIAAAVSVRANAPNVFAATPKNRTLISQSFTPPNREGKSPVTAGAATRGGCDTKQNLVTPLMPKEKLGLTFDERPTFYWHTSKSNAETAEFLLLDDNDDLVYEANVNLPKKPGIFAFTLPPEAPGLKTNKQYHWYLSVNCSSEETDDIVTVEGWVERTKPNLATWIKLNKSTPKYRSKIYADASIWHEAITNVAQQRCIAPYDSTMVLYWNQLLTSVGLKELVSESITNVCEVKNDDNK
>NC_019678|7907518:7956560|7925270_7928066_+|WP_015122157.1|bacteriocin|DBSCAN-SWA
MNIDKNAPKNEFIFKANQPLLLDDPSVVWMIESGTVALFAVVIQDGIPVSERRYLFSCNPTEALFAIDSTKVKSIVTSNDNNDHPKKYGILAVAIEEASLTQILQDDFEALRSNDSTRLIPKSAGKEFIQLAETWIEKFSIFPGVVNASSIFDTSVAYTWDDASVLHTWERVSEKLGHLHRDFLRYFEKLEQDESQEKLAQFQAREQLNRRVTETSLRELASIFKTKSQGFIQEDSELLMAAGAVGRTLGITIRPPVKSEDLNRVKEPIEAIARASRIRMRRVILTPNWWKKDAGPLIGYVGEEKRPVALLPASSGNYDIFDPKICKRIPLEKFIENEELEPVAYMFYRSLPEKASKAIELIKFAVRGRLKDLAVVIIAGVIGTLLGMLTPQATSIIIDKAIPDADRGLLVQISFGLLAASFGTAVFQLTQSFASLRLESSSDATTQAAVWDKLLTLRMSFFRAYSIGDLQSRVSAISQMRQYLSSSTLQTIFTSFFSLLNLALLFYYNSRLALVAIGVAVVSIIITSISGIITRRKLRPLEEIQGDISGLMVQLIGGVSKLRISGAENRAFAHWSKKYTKQLKLMLSSQLIEDLVGLFNILIPTIASIIIFALSANLMFGANTQNPQASPPLTAGTFLAFNSAFGTFMGGVVGLSNTIISILEVIVLWGRAKPILIATSEIDLSKADPGKLTGTVELEHISFRYREDGPLILNDVNIKAAEGEFIAFVGPSGSGKSTIIRLLLGFDTPEVGTVYYDGQDLSGLDISAVRRQLGVVLQNGRISSASIFENISGGALITMDEAWEAARMAGFAEDIEGMPMGMHTVISEGGTNLSGGQRQRLLIARSLVLKPKILIFDEATSALDNRTQAIVSESLDQLQVTRIVIAHRLSTIRNADRIYVIEAGRVMQQGNFEQLSQQEGLFASLMARQMA
>NC_019678|7907518:7956560|7928194_7931458_+|WP_015122158.1|DBSCAN-SWA
MLATEPLKLDSYLRTLVNKASYLTERLNQDVVPTVSKSDESTINSHLEFWCQVLAKGNKEQFQRRLAADKLDIDKLHTLLGEVEYPQSQPLPAWGQTLKLVLQAAQKPLNTELSDFSSENPIPFEPFYQPFIQVAQNQLLSRVDLDILGEDAQKTLWISLLDRLRNIAIKTLFTEFAEFRSSGNSLKDFFLIQLQGKNSQEKYHAFLKHLFQDGLLGLFEKYPVLAKLLATAIDYWVDATVEFINRLRTDLPAIEKLFSPDTALQKVVELKANLSDLHNQGRSATALTFDTGLKLVYKPKDVEMELAYNKIISWCNENGSPLPLKTFTVLSQAKYGWVEFVYQDDCPDEAAAERYYQRAGMILAIMHLLLATDCHHENLIASGEHPVLIDLETLLTHQTTKSHDSNSEIPQSAFDILDKQLEKSLIRTMLLPQKGLIAKDSVEIDLSGFGGVEEYKSAMPKLRYVNTDGMNIAYEIISIESHANVPKVNGVNLSPLSYVESLVTGFEQMYRFLKNQKQALLKPGSPLMELANQKVRYVFRATHIYHSIIQDSYSPEYLDSGIKRSLALEVLARAFVVNEAMLNRISILNAERQAAEDGDIPFFAVNTSESNLPLPTQEVVTDLFIQPSFTAAINQLENLNQTNLAQQVAVIRGTFAARYTKEPALSANSVAVNFKENLKEDVIAPDIFVEQAITLANELKQTATFGEDGSVAWLGLGYRTTTEGFLFQPLGSNLYDGNCGIALFLAALAKITQDSQWSNLASHSLQPLLQIHKTESSERLARFTRKMGIGGATGLASIAYTLVHTSKLLADNNLLTTAKNIALLITPESIASEKYFDITRGVAGAILGLLAVYKTNPEDKRLLDLAINCGEHLLKQQISINEYKTWKTWNGIALTGFSQGAGGIAYALLNLCKITAREEFLQAAKEAIAYEKSCFCEEAGNWQDLRTENNQYQVSWAHGAAGIALARINSLSILNTPEIIAEINTALETTQKCGISTVDNLAWGNFGRIETLLVAAQVLNRPELLQIARNSSIKLVEQAREKGGFRLYSNILSPVFNPAFLHGTSGIGYQLLRLAYPELPSILSFEF
>NC_019678|7907518:7956560|7949489_7950308_+|WP_015122174.1|DBSCAN-SWA
MTKLLFLGSGCAFTVGTDNYQSNMLLITDTGKKFLIDCGSDIRYSLYRQGFSYLDITDIYISHIHADHVGGLEYIGFSSKFDPRCQKPRLYTDKEIMHNLWNNSLSGGMKYIENEIVTLEDFFKPIEIDEDKAFYWENIKFNSIKVIHVNSASVVTPSYGLFFEINGIKVFLTTDTQMHWNSLGKLYQQADIIFQDCETAKFPSGVHAHYQELLDLPLSIKNKMWLYHYQPGKLPDAKKDGFCGFVQRGQEFDFSSSIFAENNFTAINSTFV
>NC_019678|7907518:7956560|7935452_7935782_-|WP_015122164.1|DBSCAN-SWA
MSTQTVNQFFEKVSEDPELQQKLVKAIESENDRQAVTDLAAQEGFQFTSDELWEEIKNRQQAIIDSGELSEEELEAVAGGATPAGALVVTIMGASGAIGGAVIKRYAKW
>NC_019678|7907518:7956560|7907518_7907932_-|WP_015117596.1|transposase|DBSCAN-SWA
MAKLSASDYEYRRAEKSVSSINYHFVFVPKRRKAVLVNEIAMRLQEIIFELVKEHGWRLIALEVMPDHVHMFINSPPHESASQIAKWVKGRASNILRKEYPQLKKLPTLWSPSYFVATTGQVSTDVIRKYIENQTSK
>NC_019678|7907518:7956560|7942964_7944116_-|WP_015122170.1|DBSCAN-SWA
MELQDLRANILVSYGANSVEVAELLAYNKNVFDYSCLSKAINFPLASEAHVNTWKSYASEATSKGVFQTLKEKLVQLRFPISPGISQTSAYQAATRKGIVADCIDKNPGLLLRAPEKLQLRIHPSIAGEIPVIITDNRLDFVSLVQALTMRNEPKDIPASMGACMVGGFNNWDRIHQYRQEWQANNPNSTETDWNIEFRQLIPRKQLYQDRFIILSQSCYSNVSAEKLGLSATEWQNLSLTIRLEHECTHYLTKRLFGSMRNNLLDEFIADYRGIVSAAGNYRDDWFLNFMGLESFPNYRQGGRLENYRNNLSETSFEILQKLVYNASRNLKSFETEQVNKIDGAIMLAALCQLTLEELASDDIAAKIHQAISRIQQDKICIS
>NC_019678|7907518:7956560|7917659_7919144_-|WP_015122152.1|DBSCAN-SWA
MSGIFSFSGRYRILHLTWFAFFLSFVVWFNFAPFATAIKTEFGLEPAQIRTIAICNVALTVPARIIIGMLLDRLGPRITYSCLLIYAAIPCITFALAQNFTQLVISRLALSIVGCGFVIGIRMVAEWFNSEEIGLAEGIYGGWGNFGSAASAFTLPTIATITAGLTASQLNWRLAIASTGILAALYGAFYFFNVQDTPPGKVYQRPESSAGLEVTSKKDFWFLLAMNVPLVGILGVIAWRLQKVGLFGTGTMYLIFAALVALYLFQTFNIFKANKALMTGAKKYPAADRYQFSQVALLELAYIASFGSELAVVSMLPTFFETTFGLATALAGAIAGTYAFMNLLARPGGGLLSDKIGSRKWTLAITLAGTGIGYLIFSSLGKIALPLIVIMTMCASFFVMATEGATYAIVPLVKHRVTGQIAGYVGAYGNVGAVAYLTIYSLLPEGGGGDQFFFQMLGVVALIVASLCAFFLKEPTEGHGEPELHLTPEGSSRI
>NC_019678|7907518:7956560|7939507_7941319_+|WP_015122168.1|DBSCAN-SWA
MLVSEILRFLPDSLEWMVLFDLPAIQKLTNLSTIKAMYHLPEDIDLEPHSHIVLTSAGRFLAFQNQLKLVEAISQEELSVELTSSLANRFQNRLKLVPVDESHCLGLGEQPPFSPVILHLRLENDLGRATAIFEREPSFEHYELLRAVGVKFTGGELKDDYYLARFQNRLPVHIHAGILSHFSRTAHCNIFFFQHGNIDNALEDGLLKASQVRINWTKQQCLQSLTQLATISCEKTLSMTCQPPAPQKPFAYGDLVPLGFVLKALNEVDTKENSELDTAKQKLQQFLLNQQQDQLWAFHTQRLITATDSSLVLLGLDKPESVEALERFSDGEGGYYPQLWSKYQEPGKMLLDESCSHWCQPDYATTCLVRWLRNSAGLETKTDLEYLADGFSQRAGLYFANPYLVDWMLAEAIREDKNAATLRERLLVEIIASMNEDFSFGKYDVALSTALGILTLAALGVSDRTICAAQLRLLELIGEKSSISIPFYSTLCHDSELNSQEKLALQLNETFTRSKDGQKQIRSINGQLHSISLYLDTHEMITTAICALALDRNSDLNKWQVNRNSSNSNYSNSCHPRYQCKTHSQYIAKFALPPYLKKCAVSL
>NC_019678|7907518:7956560|7941466_7942939_+|WP_015122169.1|DBSCAN-SWA
MQIHMIGHASIFVKTQDAKILMDPVLWDPFCEGLNETCPKRELIPEKLPEFDFLVISHQHLDHFDLRSLAYLPKNIDVLVPKDALIIDSLRQLGYSNIYPLKEFQKVRIGSTTLMTTRSEVRVPEFGMVFADDSGVFWNTVDTYFAPPTIQAVKAIYPQIDFLLATWHISLENKYQQNKNTEFPFELYGQLMNLIQLVEPQAIAPGAQGWKYINEAAWQNQIVFPLTRERFCHDIKQVLPDINNNIFVLDPGDILTLERGDYNLESAGCDYVKTIVDDRECLEFAPVKVGANLIDPNSDRHDIDLMQQTIHQALRVDLCDFIKEYQHNLFLNNQRWQVIYQLEITYPEITETYHIDFSNSKIKIKEGRNPLANLFTYITASSLYNLINKKIDWDYLYCSGEYRNFHKVYSLAKLGILTPAEDTLLDPISIKYSSEYVAGEHIKTELSKIMETHDISIPNNSNIEEKSSTMLNLGNILIKMKKNQKESTIS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015117596.1|7907518_7907932_-|transposase	IS200/IS605 family transposase	A0A1L2BWN1	Bacteriophage	2.4e-38	56.9
WP_015117597.1|7908001_7909414_+|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1L2BWW3	Bacteriophage	4.4e-60	39.9
WP_015122150.1|7909735_7914205_-	CHAT domain-containing protein	NA	NA	NA	NA
WP_015122151.1|7915035_7917285_+	adenylate/guanylate cyclase domain-containing protein	M1HLN3	Pelagibacter_phage	3.3e-33	26.2
WP_015122152.1|7917659_7919144_-	NarK family nitrate/nitrite MFS transporter	NA	NA	NA	NA
WP_015122153.1|7919764_7919941_+	hypothetical protein	NA	NA	NA	NA
WP_015122154.1|7920291_7922532_+	filamentous hemagglutinin N-terminal domain-containing protein	NA	NA	NA	NA
WP_044292536.1|7922584_7924009_-	mechanosensitive ion channel	NA	NA	NA	NA
WP_015122156.1|7924061_7925252_-	TerB family tellurite resistance protein	NA	NA	NA	NA
WP_015122157.1|7925270_7928066_+|bacteriocin	NHLP bacteriocin export ABC transporter permease/ATPase subunit	F2Y2R6	Organic_Lake_phycodnavirus	4.1e-17	27.0
WP_015122158.1|7928194_7931458_+	type 2 lantipeptide synthetase LanM	NA	NA	NA	NA
WP_015122159.1|7931673_7932642_-	FkbM family methyltransferase	A0A0N9QAD0	Chrysochromulina_ericina_virus	4.7e-05	26.4
WP_083894164.1|7933858_7934185_-	Nif11-like leader peptide family natural product precursor	NA	NA	NA	NA
WP_015122162.1|7934308_7934623_-	Nif11-like leader peptide family natural product precursor	NA	NA	NA	NA
WP_015122163.1|7935002_7935332_-	Nif11-like leader peptide family natural product precursor	NA	NA	NA	NA
WP_015122164.1|7935452_7935782_-	Nif11-like leader peptide family natural product precursor	NA	NA	NA	NA
WP_015122165.1|7936146_7937616_+	hypothetical protein	NA	NA	NA	NA
WP_015122166.1|7937680_7938301_+	2OG-Fe(II) oxygenase	NA	NA	NA	NA
WP_015122167.1|7938342_7939443_+	hypothetical protein	NA	NA	NA	NA
7939002:7939017	attL	NA	NA	NA	NA
WP_015122168.1|7939507_7941319_+	hypothetical protein	NA	NA	NA	NA
WP_015122169.1|7941466_7942939_+	hypothetical protein	NA	NA	NA	NA
WP_015122170.1|7942964_7944116_-	hypothetical protein	NA	NA	NA	NA
WP_015122171.1|7944178_7946389_-|bacteriocin	NHLP family bacteriocin export ABC transporter peptidase/permease/ATPase subunit	W8CYL7	Bacillus_phage	1.3e-34	25.0
WP_044291278.1|7946518_7948132_-|bacteriocin	NHLP bacteriocin system secretion protein	NA	NA	NA	NA
WP_015122173.1|7948462_7949239_+	DUF928 domain-containing protein	NA	NA	NA	NA
WP_015122174.1|7949489_7950308_+	MBL fold metallo-hydrolase	G3MAC9	Bacillus_virus	2.7e-25	33.5
WP_015122175.1|7950415_7953079_+	CHAT domain-containing protein	NA	NA	NA	NA
WP_157229355.1|7953180_7953342_+	hypothetical protein	NA	NA	NA	NA
WP_015122177.1|7953554_7954847_-	nitrogenase molybdenum-iron protein subunit beta	NA	NA	NA	NA
WP_015122178.1|7955282_7956560_+|integrase	site-specific integrase	NA	NA	NA	NA
7958771:7958786	attR	NA	NA	NA	NA