CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_019700	Oscillatoria acuminata PCC 6304 plasmid pOSCIL6304.01, complete sequence	0 crisprs	NA	0	0	0	0
NC_019694	Oscillatoria acuminata PCC 6304 plasmid pOSCIL6304.02, complete sequence	0 crisprs	NA	0	0	0	0
NC_019693	Oscillatoria acuminata PCC 6304, complete genome	82 crisprs	csx1,csx21,csm3gr7,csx19,csm6,csm2gr11,csx10gr5,cas10,csx3,WYL,RT,Cas14u_CAS-V,csa3,cas3,PD-DExK,cas14j,c2c9_V-U4,DinG,Cas14c_CAS-V-F,cas14k,cmr3gr5,cmr4gr7,cmr5gr11,cmr6gr7,Cas9_archaeal,cas2,cas6,csc1gr5,csc2gr7,cas10d,DEDDh,cas4,cas1	15	30	5	1

1. NC_019693

CRISPR-Cas detection and classification

Crispr_ID: NC_019693_1

• CRISPR_ID: NC_019693_1
• CRISPR_location: 132403-132488
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_1

Consensus_repeat	Method
CACCCTTCAGGGTGCGGGTTTTTA	CRISPRCasFinder

spacers of NC_019693_1

>1.1|132427|38|NC_019693|CRISPRCasFinder
TTCTTAGCCCGCGCAGGCGGGCTTCGTCCGTATAGCCC

CRISPR arrays and Neighbor proteins around NC_019693_1

CRISPR arrays

The CRISPR arrays of NC_019693_1

>merge|NC_019693|1|132403-132488|CRISPRCasFinder
CACCCTTCAGGGTGCGGGTTTTTATTCTTAGCCCGCGCAGGCGGGCTTCGTCCGTATAGCCCCACCCTTCAGGGTGCGGGGTTTTA

>NC_019693|1|1|132403-132488|CRISPRCasFinder
CACCCTTCAGGGTGCGGGTTTTTA	TTCTTAGCCCGCGCAGGCGGGCTTCGTCCGTATAGCCC
CACCCTTCAGGGTGCGGGGTTTTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_156824007.1|136536_137181_+|DUF1997-domain-containing-protein	unknown	unknown	gnl|CDD|370453
NC_019693.1|WP_015146519.1|140337_140766_-|DUF2358-domain-containing-protein	unknown	unknown	gnl|CDD|370865
NC_019693.1|WP_015146521.1|144179_144614_+|hypothetical-protein	unknown	unknown	gnl|CDD|223894
NC_019693.1|WP_015146515.1|135416_136076_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|215072
NC_019693.1|WP_015146507.1|118803_120693_-|hypothetical-protein	unknown	unknown	gnl|CDD|197231
NC_019693.1|WP_015146502.1|109591_109903_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146518.1|138520_139993_+|ankyrin-repeat-containing-protein	unknown	unknown	gnl|CDD|222980
NC_019693.1|WP_156824006.1|120670_124621_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|372468
NC_019693.1|WP_015146517.1|137550_138024_-|DUF4079-domain-containing-protein	unknown	unknown	gnl|CDD|372553
NC_019693.1|WP_015146506.1|114168_117354_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|225183
NC_019693.1|WP_015146513.1|132491_134051_-|M48-family-metalloprotease	unknown	unknown	gnl|CDD|320692
NC_019693.1|WP_015146511.1|128864_129869_+|ATP-binding-protein	unknown	unknown	gnl|CDD|223540
NC_019693.1|WP_015146505.1|111613_113626_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|130902
NC_019693.1|WP_015146522.1|144676_145534_-|DUF1206-domain-containing-protein	unknown	unknown	gnl|CDD|377695
NC_019693.1|WP_015146504.1|111159_111567_-|HetP-family-heterocyst-commitment-protein	unknown	unknown	unknown
NC_019693.1|WP_015146520.1|141024_143952_+|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl|CDD|234734
NC_019693.1|WP_015146512.1|129870_132351_+|S8-family-peptidase	unknown	unknown	gnl|CDD|173793
NC_019693.1|WP_015146514.1|134423_135131_-|glycoside-hydrolase-family-protein	unknown	unknown	gnl|CDD|227023
NC_019693.1|WP_015146503.1|110001_110313_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044196181.1|126146_128243_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|270916

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_156824007.1|136536_137181_+|DUF1997-domain-containing-protein	gnl|CDD|370453	pfam09366, DUF1997, Protein of unknown function (DUF1997). This family of proteins are functionally uncharacterized.	1.7871e-60
NC_019693.1|WP_015146519.1|140337_140766_-|DUF2358-domain-containing-protein	gnl|CDD|370865	pfam10184, DUF2358, Uncharacterized conserved protein (DUF2358). DUF2358 is a family of conserved proteins found from plants to humans. The function is unknown.	5.15396e-50
NC_019693.1|WP_015146521.1|144179_144614_+|hypothetical-protein	gnl|CDD|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	1.42004e-17
NC_019693.1|WP_015146513.1|132491_134051_-|M48-family-metalloprotease	gnl|CDD|320692	cd07333, M48C_bepA_like, Peptidase M48C Ste24p bepA-like, integral membrane protein. This family contains peptidase M48C Ste24p protease bepA (formerly yfgC)-like proteins considered to be putative metallopeptidases, containing a zinc-binding motif, HEXXH, and a COOH-terminal ER retrieval signal (KKXX). They proteolytically remove the C-terminal three residues of farnesylated proteins. They are integral membrane proteins associated with the endoplasmic reticulum and golgi, binding one zinc ion per subunit. In eukaryotes, Ste24p is required for the first NH2-terminal proteolytic processing event within the a-factor precursor, which takes place after COOH-terminal CAAX modification (C is cysteine; A is usually aliphatic; X is one of several amino acids) is complete. Mutation studies have shown that the HEXXH protease motif, which is extracellular but adjacent to a transmembrane domain and therefore close to the membrane surface, is critical for Ste24p activity. Several members of this family also contain tetratricopeptide (TPR) repeat motifs, which are involved in a variety of functions including protein-protein interactions. BepA has been shown to possess protease activity and is responsible for the degradation of incorrectly folded LptD, an essential outer-membrane protein (OMP) involved in OM transport and assembly of lipopolysaccharide. Overexpression of the bepA protease causes abnormal biofilm architecture.	4.76108e-69
NC_019693.1|WP_015146507.1|118803_120693_-|hypothetical-protein	gnl|CDD|197231	cd09133, PLDc_unchar5, Putative catalytic domain of uncharacterized hypothetical proteins with one or two copies of the HKD motif. Putative catalytic domain of uncharacterized hypothetical proteins with similarity to phospholipase D (PLD, EC 3.1.4.4). PLD enzymes hydrolyze phospholipid phosphodiester bonds to yield phosphatidic acid and a free polar head group. They can also catalyze transphosphatidylation of phospholipids to acceptor alcohols. Members of this subfamily contain one or two copies of the HKD motif (H-x-K-x(4)-D, where x represents any amino acid residue) that characterizes the PLD superfamily.	3.47439e-16
NC_019693.1|WP_015146520.1|141024_143952_+|excinuclease-ABC-subunit-UvrA	gnl|CDD|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NC_019693.1|WP_156824006.1|120670_124621_-|AAA-family-ATPase	gnl|CDD|372468	pfam13087, AAA_12, AAA domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.	2.3349e-58
NC_019693.1|WP_015146517.1|137550_138024_-|DUF4079-domain-containing-protein	gnl|CDD|372553	pfam13301, DUF4079, Protein of unknown function (DUF4079). This is an uncharacterized family of proteins.	4.12223e-52
NC_019693.1|WP_015146506.1|114168_117354_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|225183	COG2274, SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms].	0
NC_019693.1|WP_015146515.1|135416_136076_-|SDR-family-oxidoreductase	gnl|CDD|215072	PLN00141, PLN00141, Tic62-NAD(P)-related group II protein; Provisional.	9.87326e-68
NC_019693.1|WP_015146511.1|128864_129869_+|ATP-binding-protein	gnl|CDD|223540	COG0464, SpoVK, ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones].	3.91059e-36
NC_019693.1|WP_015146505.1|111613_113626_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	gnl|CDD|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	1.11056e-40
NC_019693.1|WP_015146522.1|144676_145534_-|DUF1206-domain-containing-protein	gnl|CDD|377695	pfam06724, DUF1206, Domain of Unknown Function (DUF1206). This region consists of two a pair of transmembrane helices and occurs three times in each of the family member proteins.	9.40061e-16
NC_019693.1|WP_015146518.1|138520_139993_+|ankyrin-repeat-containing-protein	gnl|CDD|222980	PHA03095, PHA03095, ankyrin-like protein; Provisional.	2.29803e-29
NC_019693.1|WP_015146512.1|129870_132351_+|S8-family-peptidase	gnl|CDD|173793	cd04847, Peptidases_S8_Subtilisin_like_2, Peptidase S8 family domain in Subtilisin-like proteins. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	3.19785e-99
NC_019693.1|WP_044196181.1|126146_128243_-|tetratricopeptide-repeat-protein	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.13673e-56
NC_019693.1|WP_015146514.1|134423_135131_-|glycoside-hydrolase-family-protein	gnl|CDD|227023	COG4678, COG4678, Muramidase (phage lambda lysozyme) [Carbohydrate transport and metabolism].	3.72432e-61

Protein sequences

>NC_019693.1|WP_015146512.1|129870_132351_+|S8-family-peptidase
MAKKSRDFPHLYVEGTGKSESYKSSGRGSSGDPPERDRKAHAQFLEEAIGRALEKAERQLKSRDPQIPTEPPGFYLEFQIKAEETTALKSLENRSKKIELVAVSQLDEPAGMVKATVFVPKSATDYFLKKIQEYRDKDTDKNKPKNQALIARLEGVDIGTVQSLFTDAPALFPPNNQEVWWEVWLRKGRKEAFNSLTANLNLRTKPDELSFPEHDIVLALCNLEAMARVIKHSDAVAELRIAKDTPSFFLEMKGREQEEWVQDFANRLVASGKQAVSICLLDSGVMQRHPLLTPGLDPQDMHTVNENWGVNDSATWKGHGTAMAGLCLYAESLMDFLATSDSVKLLHRLESVKILPNSGKNDPALYGAITGQGVSLPEILFPDRPRLFCMAVTSNTQSNNRGTPTSWSAAVDQLCFNDGEFRRLIIISAGNIREDINGADYLTINELEPIENPGQAWNALIIGAYTEKVNIIDANYVGWKPLAPGGELCPRSRTSASWDRHWPIRPDVVFEGGNMAWDGQNPAESINDLGLLTTHYRPNFRMLDYISDTSSATALASYMAAQIMSKYPDFYPETVRGLIVHSAEWTSAMQAHFIAASSKRNRGNLLRRYGYGVPDLTRAIKSAKNDLTLIIQDKIQPFHVEKSHVAMKEMKLHKLPLPTDILEGLGEATIELKITLSYFIEPNPGERGWAYRHRYPSHGLRFQVKDSLETDEMFRKRINLAARENEEDFSWNRQSDNNKWFLGPNARDFGSIHSDIWQGTAVELAAKDTIAIYPVGGWWKEKKYLDRYNEISYYSLLVSIRVPEVEVDIYTPISNLVSMTVPLDNL
>NC_019693.1|WP_015146511.1|128864_129869_+|ATP-binding-protein
MSTARQIIALLKSHIEGEEQQFYSAALQIAASEARQGHGKLALEIRDLINEAKNRKSAIAPKPGIVPLVQPKGELGNLVSVRYPDTKLRDMVLSPELEFRLNRIITEQKQRNRLQEYNLSPRRKILLVGPPGSGKTMTAAALGGELQLPLFTAIYSSLMGKFMGETASRLQLIFDAMSATRGVYFFDEFDAIGTQRNSANDVGEIRRILNSFLLFIENDPSESLIIAATNHPNLLDEALFRRFDDVIEYSFPSPSMIQSILETRLVLFDLEWEDWSEILTSAENLSLADIVRAADEAAKQAILSHTEKIDREHLLYAILDRKNITRTPLLNASS
>NC_019693.1|WP_044196181.1|126146_128243_-|tetratricopeptide-repeat-protein
MLGTTLGGRYKIVNSLGSGGFGATFLAQDCHLPGTAPCVVKQLQPQSTDPNTLQVARRLFDTEAESLHELGSHDRIPKLFAYFEENQEFYLVQEYIEGQDLSQELTPGEKLDEKVTLDLLRELLEVLQFVQSKNVIHRDINPRNILRRNSDKKLVLIDFGAVKQITTELLNPNGKPGFSVCIGTPGYLPSEQATGFPKPSSDIYAVGIVALQALSGLLPHEFPKDPETEEIKVAELVTVSPEFLKVLERMVRYDFRERYGSATEALEAIADLEKPTMMTVSVPGVTPLPQPRFKVSKPQWVLGVISCGIIGMGMIAGSVFVWNKIKSVNASELYHQGHTLYHLSRYEEALKRYENAIEIKADYVEAWKEKGDTLSRLNQNEAAMDAYDRAIQLNPEYLDAWIRRGDVLNRLQRYDGAIASFEKAIELVPESAEAWNGKGNTLLSLQRYEEAIAAYDQALEFQPESSEAWYARGWAFHQLKDYEAALKSYDKSVEYQFDYAVGWYNRGNVLMQLNQAKEAVESYDKAVRFQPNYAEAWYSRGNALMQLNDASEAAKSYERAVKLQTNYQEAWYSLGWALHQLRRYEQAIEAYNQAIDLKKIDYRAWYNRGNALYNLNRYQEAVSSYNEAAYVKPDHAESWYGKGNSLSTLGQYEEAILAYDRALRYQPNYRAAKEGKERAQRQIKQREKRDSPGDGNRE
>NC_019693.1|WP_156824006.1|120670_124621_-|AAA-family-ATPase
MTRGRGDGFTVLCRLRLLPDHQYDLGVPRSALKRMAKLPVSGDLIPTEEQLQAWRVYVEIEKRIAESRQFCVPFIGHNYGADARRISFELDSREATIDGSNETELAAGEFWSRTYKARSEQLRLFESSPLGKSGRDGRILGRIDSVDTERRLLRIKPDADLLELMAGGYYQLPESGYLFFEAFGELSQINHKMNALKRLEQGHSQNPFLGQFFFDAGQARVPKQLIKLERAELLLPAANPDQIAAVEMVLSAKDLVLIQGPPGTGKTTVIAEICYQVARRGGRTLIASQANLAVDNALSRLVHSPVIRALRKGKAEKVQEEGAPYLEENAIGTWLQNTASHCETDLEKRRNDLAFYHKMQKVAAEFEVYLAAEEALASDRLFWKERQESLLENRAIWEQQYQAAQDQNPEVKRVSAELAGLLAAAPNVQWESPDVVKLLAEIRPYTLEDSRVKTFIDAVRVALPLTQELGWIRPDRGAFGLAAWCCETVAPELAKLREVVTEANRTAEAIAAAATAVHQFRADSTPLQQLQGEYDQALTKQKSLQQRFQNLQTRKLEIDRVIKEVGVWLETAPAQVYTILRQAIQTGQPFNSKLIHVPDSLLAIAQTLNVAIMPNYGNYPVTELPNWEQFLKALAYETKGNFRNTKGNHSYFNEFLHRSLNQPPIVFSGGDRTLWRELAAGYGNYPQLTTSGRQNLVIKTQEVLQQQQQQYATLWQVQAVELTLQQIAQTTIDEIVTQARQCLLPLKTETEQGLSHIGQQWHQIQHWIAAQKPQLEQSQAALEVARKEGEETLKQALSQLQQLSQQPHLPPAILTGVQRYQANRALIWEKPAEFATLVQSWESRIANLETAIAALAPFEVLGHIHSLIEAYLTQQQQNLQPLQQQLEQCELELHEITQQLTTNLPEPLLNHRNWWRQTWETLGDRLPQISEEHCCDLPFLHQVKTQFETWEQAGNQEEQYLDRYQNLVQDWIDKLRHPSEQDRNELRQIYLDNANVIGITCVQAARRDFSDEFNKFDVVIIDEVSKCTPPELLIPALKAKRLVLVGDRCQLPPMLNDDTIEDIAIEMGSSKDALQFLEDSFFKLQFDAAPESIKTMLTIQYRMHPNIMGAINQFYDRRLQCGILDPDQARKHHLDSAIIQEHQHLIWVKMPQDSTFGERKEGTSFINPKEIEAIEQLCQDMENTWSEKIAQGHPPKEIGIITFYRAQLNRIEERILDENRFPSLQIRTGTVDQFQGMERSVIIVSMVRNNSEGKVGFAKKSERVNVAFSRARELLVIVGCHQLFAHHHGEVGRIYSEVSNVVRHQGGLIDVSRILP
>NC_019693.1|WP_015146507.1|118803_120693_-|hypothetical-protein
MFLESSPKPIDSSLQPSVAKLEKTSPGLSVIAAKQFRYALVQTGIELMVTAPRKFNVLEEFILRASLEITPKPTEVELAQVLGLDPIFVRSTTANLQALNTLNVLPDGSLQLTPEGRTFYEKGSVPQPPESHSLYAIADPLLEATTFELNPLRESALNLPNLGDFLPLNCRIKPVDSLTLTEVQQRLIHQGLGFHSPESGKEVTAFKIAEPPETRWQSVALFAIFDTLNQRLTLQLRRGQQLLESATLWLEMLQSEGKISLTELFEIPCKESFPQENYAVEARLEQVRTAATTKGDNAGENTPETGSVILIPESQIQTQFLETLKTANHQVLIYLPQFPEQGIDYRLLQGLETLVKRGVWILMGQGTVSEELSENPPILPEWLTKLAAVKTAEGLSAIQILELEQFHAKEVVIDRQIYVCSAPNWLTYGGDCLPQGESLYQVTVPEIISAAYQFLSTQFQQRAESLWQEAITTQDESLATISLSIWGGLGMTEIALQQIQDQGWLELLPIWLKIACQGLRSQQLSSDSPSLNQALSQLSELTPDFPELDSLCEAWRQVMGVIASGDRTLALKLLSEAVWQDFTRLGIAPETIESPDTFISSELAQLSQNQPRVKSKNTQPQKRSRSKSD
>NC_019693.1|WP_015146506.1|114168_117354_-|ATP-binding-cassette-domain-containing-protein
MKETFQKNKFHESSRVSSVHPLDNLPTLMQILPADSRESTTTVELAKAFDVQGFQIGDELLCVGESDPGMTENQMPLHSDCYFIDQGRVRLLVFDAERQREICAMVLEKGESFGGDEWLNQKPIPYRVVAASDGVVSRISPEKLRPLLEQEPAIQAYLSEQTTQRQCQLFLKTVPELRSLSSHQIRQLLPYLQEKSIPAHASLVEVTPTSQGHYWLRHGEIQRGTETSQVQIQATGTSWGYPQETPTDWIAATELEIIELPVVQWESATAIAPVLTGEYGNGNGNGNGHRRSPTRILQRPAPPVMTPVPGPQSSRDNGNSRPDGSDPRSAQNPVLFPKPNHRRFLDLLARYPHIQQQSSSDCGAACLVMIGQYWGKRFSINYVRDLAGVGRSGASLKGLAKAAENLGFHALPVRGSLDRLADRKNPWIAHWQGIHYVVVYKITPHRILVADPAEGKKWVKRQEFLTHWTGYALVLDPTERLKEAKTEKRSLGRFMSALVPYRNLALQIVAFSILIQIFGLIQPLFTQIILDQVVTQQSLSALNLFCLGALIFGLWSKGLSAVRKYLLSYFSNRLDLTLIGGFIRHAMMLPLKFFESRRVGDIITRVQENRKIQQFLIGQVVLAWLNFATGFVYLGLMLYYNARLTLLVLALIPFIIILTLLATPILRKVSREAFNASADQNSSLVEMFTGITTLKSTATEYQMRWRWEDYFTKALNVRFKGQKLGIGLEVLNSTINIVGSIALLWYGGRLIIQGDLTIGQFVAFNMMKGRIITPVLALANLWDRLQEVLISVERLNDVFETEPEESPGSAMMVLPPLRGDLRLENVTFRYSEDDERNTLENISFEVKAGQTTAIVGRSGSGKSTLVSLLQRLYSPNSGRIFIDGHDISHVSPSSLRSQIGVVPQDCFLFSGTISENITLYSDEFALDDVIEVAKMAEAHPFIQEMPLGYNTKVGERGSSLSGGQRQRIAIARALLGNPRILLLDEATSSLDTESERRFQQNLARFSRDRTTFIIAHRLSTVRNADCILVLDRGLLVERGTHEQLMEQQGLYYHLAQQQLDL
>NC_019693.1|WP_015146505.1|111613_113626_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit
MNFHLGPDYPFTHPSRRNSQEPSSRHRGSLHLLDTACDVDVGTETVEAGDRAAAIYGGMAASDAMPRTVSDRDDDHSAHWSSAMQNLLDRPPASFPTQLLLGGMAFCIAFGAWSWFGRINEVGQAVGELIPQGDVYQVHPLEMGKVAKVGVAEGDQVQAGTVIAELDTQLAATEVDRLGEQLATYQMQLVQKQALMENTALEAETRGAIAKADAQAHQTLIAQAEKNVTTTQNLLTQLQADAAELEARRQTLAPLAGQAQQLVQQLQGDIEAQRKRGEILKPMENQTRELIERLETDVTAQQQRQQLLEPMQEKTQALIEQLKVDVAEQQERVERLSPLVDEGALSREHLFQAEQSLRDRQNALTRAEMVEATQAEERMFEAEQAERDRSNAVLRAQMSEVTSVQERMFEAEQALRDRQTAALRSQMSEATIAQERLFEAEQALRSHRQRITDTQAQLEQRESELAQLQAQQIQKQAEAERLEIESQQRIKQLQVEVTQLEGSIAQTHNRLTSAKAQLNEQFLYAPVDGTILALNISHPGEVVQPGQTLAQIAPEDAPLVLSAIIPSQEAGFIQTGMEVQVKLDAYSFQDYGVIPGEVTSISPQANADPQLGSVYNLEIALAHNYVTENGEKIYFKPGQTANADIIIRERRILDVILDPIRKLQDGGMNF
>NC_019693.1|WP_015146504.1|111159_111567_-|HetP-family-heterocyst-commitment-protein
MTYQMHYSNRNLDKIMTQEQFELVVDAILAGKYSWACVLILRFGGYNPLHYIPYRTYNRLMKQQRQGRQESGHRTKDDYSDQEQDKGNNSQDGNHKIKDLTYLEVVEHQSHQVTGGSTALYASESTALGNVISFQ
>NC_019693.1|WP_015146503.1|110001_110313_-|hypothetical-protein
MIISDLNHLEVVNQETQVVGGWGGNDGDLDLNIDIYKNVDVNVKEDVDIYKEFDIEAEVKGISAFAEAEAIAMGDDAHAESLTFTFTEDYFAASSAQSVSVTG
>NC_019693.1|WP_015146502.1|109591_109903_-|hypothetical-protein
MIISDLNHLEVVNQKTQVVGGWGGNNGDLDLNIDIYKDVDVNVKEDVDIYKEFDIEAEVKGISAFAEAEAIAMGDDAHAESLTFTFTEDYFAASSAQSVSVTG
>NC_019693.1|WP_015146513.1|132491_134051_-|M48-family-metalloprotease
MKRFRHALWATVGVALFLSMNLLLTFAPAHSTLPPTGVQTPAPQSKIPPFSSFKQLLELAFEPGSSEFNTLVEADRLFLAGNTQAAEQLYRQVKGQFPQHRGDQAIAEPITDPEQLSGAGRVYWREAQAGFEQGLETRIFVPLQQLVEKQPEFIPGHVLLVQALQQYGRGEEALAVLERATTLYPNEPELIKAEISALQGEEKWLESSIAARQFAVLYPEHPQSSEFEAIADNDLGRYRSGIRRRLIGQTIVTGALSIGDLLLTGNVAGTIPALQLTMLLMQGEASFGNQLAEVFQQRLPMVEDETIVNYVNEVGQKMAKLMGRDEFEYEFFVVNDKNLNAFALPGGKVFVNTGALQKINTEAELAGLMGHEVAHAVLSHGYQRVVQSALLSNLNRVVPMGDLIAALVGRAYSRQNERQADVLGSRVLANTNYAADGLRNLMQTFTELDGGGGGVLSWLSSHPASSDRLRYLEELIQRNGYNRYAFEGVERHAQIQSRVQELFPEEEAGNPVEVLLAGA
>NC_019693.1|WP_015146514.1|134423_135131_-|glycoside-hydrolase-family-protein
MLSEPSAQPLNLSQKPVVKRRRKPPKFRQFVLLLAGAIALPMLFYNVIFRRTESLEPSLIAPLPPLVMENGDPYIRALMRTISASESNVDYPYAVIYGGQYIDDFKRHPDLCVRIVAGPNLNNCTTAAGRYQFITTTWEEMAERYHPKPDGRWFWKSYSFEPKFQDKVVYAWLKDEEAWGVNIPELLKQGKLDEVLYLLSGTWTSLGYGIETNSMSASLPTIYQQLLEEELQKSM
>NC_019693.1|WP_015146515.1|135416_136076_-|SDR-family-oxidoreductase
MKAFVAGATGQTGRRIVEELVKREIPVRALVRNLEKGQQLLPPQVELVVGDVLNPESLNEAIADCTVVLCATGATPSFDPTGPYRIDYEGTKHLVDVAKVKGIEHFVLVSSLCVSNLFHPLNLFWLILVWKRQAEKYIQNSGLAYTIVRPGGLKNTEDEAAIVMKSQDQLFDGSIPRTKVALVSVEALFQPAARNKIVEIVTNAEAPAQAFPELFASVV
>NC_019693.1|WP_156824007.1|136536_137181_+|DUF1997-domain-containing-protein
MEMYADVETVAAYFDVHQGWFRRCAHPMQADALGENGYALTIGRFGALGYEVEPKIGLNLLPQQNRVYLIETIAVPDYVPPGYDVEFKAAQELIEIPADYSNIKLRHTEDLPPTMTRVEWNLDLKVGVCFPKFIHALPLPLVQRTGDRLLAQIVKQVSRRLTYKVQEDFHSTIGRDRLELFKKKRAKSSNSDLCRQCSGSNGTGEEIPEDLETP
>NC_019693.1|WP_015146517.1|137550_138024_-|DUF4079-domain-containing-protein
MTFELPAPLQTGLTFFHPLLMWVLFGLSIYALVLGVKLKRTRKATGEEKKVLIKGKYNIRHYQIGSIMLALMVFGTVLGMAATYVNNGKLFFGPHLLVGLGMTTMVAISASLAPFMQQGVAWARVTHVAMNMTLLTLFGWQAFTGLQIVQKILSSDS
>NC_019693.1|WP_015146518.1|138520_139993_+|ankyrin-repeat-containing-protein
MLSNQDLLLIQAARIGNINQVITLLAEGARVNAKDREGTTPLMFASQKGYTEIARHLLEAGADANLPREKYGITPLMFAAANHQIDVVRLLLSSGAQVNARNDDGSTALMAAALKGNLAIVDLLLTHGAQPNIKDKDDDTALKLAIVQGHIAIVQSLLAAGANLEAIADLDALLFRIAQKGNAQLLELLIQKGLSCQTYDCGSALLEAAERGDLPILQILLAGGTHPNVTDKDAETPLLLASDRGHTEVVIALLAAGADVNAKNLDGFTPLMAGASGGHWEMVRSLLDAGAEINAIDSDGETALNWAVVEGYADVVNLLLDSGADFQRCNRLGDTPLFVAALHDRADIVAALLHKGAEVNPTNFDETPLTATAELGHLNTIRVLLKAGADPNAVSTGGKTALMKAADRNLTEVMEVLIAAGADVNRQDDAGATALMWAAHRGFEEAVHLLVSAGVNVNLKNRGGYTALAIAEFNGYKKVARSLRKAGTQE
>NC_019693.1|WP_015146519.1|140337_140766_-|DUF2358-domain-containing-protein
MDEYQSQVFKAIATLKEDLPRLFEKDISYDIYRKDIFFKDPVNQFKWKFNYRIIFWTLRFHGQLFFTELYFDLHDVEQVEPDMILANWTVRGQLRLPWKADLFFNGYSNYKLDEDGLIYEHIDTWDREPKAILKQFLPRSET
>NC_019693.1|WP_015146520.1|141024_143952_+|excinuclease-ABC-subunit-UvrA
MPKRASASTKQPVQSLNGSSLTEAVVNPRDHGIRIRGARQHNLKNIDLELPRDRLIVFTGVSGSGKSSLAFDTIFAEGQRRYVESLSAYARQFLGQLDKPDVESIEGLSPAISIDQKSTSHNPRSTVGTVTEIYDYLRLLFGRAGKPHCPICDRSIAPQTIDEMCDRVMELPDRTKFQILAPVVRGKKGTHKKVLSSLSSEGFVRVRVNGEIRELSDKIELDKNHTHTIEIVVDRLIKKAGIQERLADSLTTGLRHSEGIAIIQLLDSTTDDGETELVFSEKFACPEHGAVMEELSPRLFSFNSPYGACESCHGLGSFRTFSPELIIPDSDAPIYEAIAPWADKESAYYLSVLQGLAKAYGFELTTPWNELTAKQQKSILYGADEPINIEGWGNNRRYAGALALLQRYYEESASELQKQKLDQYLVDRPCESCHGKRLKPEALAVRIGDEHIDDLTSVSIRDCRDRIDRLQLSSRQAQIAELVLREICARLQFLLDVGLDYLTLDRPAMTLSGGEAQRIRLATQIGAGLTGVLYVLDEPSIGLHQRDNGRLLHTLTKLRDLGNTLIVVEHDEDTIRAADWIVDIGPRAGVHGGEIVAQGQLDALLAAENSLTGSYLSGRLQIETPGERRKGNGRSLVMKNCSRNNLKQIDVEIPLGKLVCVTGVSGSGKSSLINDLLYPALQHHITRKTPFPGDMDALKTLGEKSLKDAVDKVIIIDQSPIGRTPRSNPATYTGVFDMIRGLFAETIEAKARGYKPGQFSFNVKGGRCEACGGQGVNVISMNFLPDVYVQCDICKGARYNRETLQVKYKGHSIADVLNLTVEEGLELFKHIPRAATRLQTLVDVGLGYIHLGQPAPTLSGGEAQRVKLATELSRRATGKTLYLIDEPTTGLSFYDVHQLLNVLQRLVDKGNSILTIEHNLDVIRCADWVIDLGPEGGDKGGEAIATGTPEEVAENSRSYTGEFLKRVLQQYPAQS
>NC_019693.1|WP_015146521.1|144179_144614_+|hypothetical-protein
MTLEQDTLLETALTFTVKPYDIDITGFVSQIIVMRWIEDLRLDLFQQYFSLEQQLELGISPLIGKTRLEYHKPIKLFDLIEGRMWFSDMGSVKWIVKTELMVDDKISVTAKQTGCFIHVASHRLVAIPDNLVKKFATYSSGGMS
>NC_019693.1|WP_015146522.1|144676_145534_-|DUF1206-domain-containing-protein
MTQSTQSTQSEWIERFARFGYAAKGFVYGLVGILALQVALNQGGQTTDPKGVLYEIVEQPFGQALLAFVTIGLIGYAMWRFLQAFMDTDNKGTDFKGLIERFGFGMSAVIYCGFAFTAIKILTGNGENGGEQSDQSAQHWTARFLSQPFGEWLVGLAGAVVIGLGFYYFYKAFTGKFRKELKIREMTPNEEKWVMRVGRVGLSARGIIFTMIGWFLMQAAYQSNANEAQAIPGTLETLLRQPYGSLLLGVVAAGLVIYGLYMGVHARYRRIHPPQGDPRQLLNQG

Crispr_ID: NC_019693_2

• CRISPR_ID: NC_019693_2
• CRISPR_location: 154571-154671
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_2

Consensus_repeat	Method
GAAAAATCGGGGTTTCTTGTAGGGGCGTATTGCATAC	CRISPRCasFinder

spacers of NC_019693_2

>2.1|154608|27|NC_019693|CRISPRCasFinder
GCCCTCTTTATCCCTCCATTGAATCCC

CRISPR arrays and Neighbor proteins around NC_019693_2

CRISPR arrays

The CRISPR arrays of NC_019693_2

>merge|NC_019693|2|154571-154671|CRISPRCasFinder
GAAAAATCGGGGTTTCTTGTAGGGGCGTATTGCATACGCCCTCTTTATCCCTCCATTGAATCCCGAAAAATCGGGGTTTCTTGTAGGGGCGTATTGCATAC

>NC_019693|2|2|154571-154671|CRISPRCasFinder
GAAAAATCGGGGTTTCTTGTAGGGGCGTATTGCATAC	GCCCTCTTTATCCCTCCATTGAATCCC
GAAAAATCGGGGTTTCTTGTAGGGGCGTATTGCATAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015146534.1|160506_160950_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146530.1|155902_157051_-|cupin-like-domain-containing-protein	unknown	unknown	gnl|CDD|372651
NC_019693.1|WP_015146519.1|140337_140766_-|DUF2358-domain-containing-protein	unknown	unknown	gnl|CDD|370865
NC_019693.1|WP_083896718.1|153584_154526_-|hypothetical-protein	unknown	unknown	gnl|CDD|226274
NC_019693.1|WP_015146525.1|148289_149771_-|hypothetical-protein	unknown	unknown	gnl|CDD|225747
NC_019693.1|WP_015146520.1|141024_143952_+|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl|CDD|234734
NC_019693.1|WP_015146532.1|158303_159863_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl|CDD|234854
NC_019693.1|WP_015146527.1|150411_153399_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|378942
NC_019693.1|WP_015146529.1|154780_155659_-|hypothetical-protein	unknown	unknown	gnl|CDD|226274
NC_019693.1|WP_015146537.1|163281_165144_+|molecular-chaperone-DnaK	unknown	unknown	gnl|CDD|184039
NC_019693.1|WP_015146531.1|157063_158137_-|cupin-like-domain-containing-protein	unknown	unknown	gnl|CDD|372651
NC_019693.1|WP_015146538.1|165931_167062_+|molecular-chaperone-DnaJ	unknown	unknown	gnl|CDD|237663
NC_019693.1|WP_015146522.1|144676_145534_-|DUF1206-domain-containing-protein	unknown	unknown	gnl|CDD|377695
NC_019693.1|WP_044196194.1|167124_167319_+|sulfurtransferase-TusA-family-protein	unknown	unknown	gnl|CDD|238180
NC_019693.1|WP_015146536.1|162332_163121_+|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl|CDD|237624
NC_019693.1|WP_015146524.1|147294_147987_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|226983
NC_019693.1|WP_015146523.1|145932_147183_+|OFA-family-MFS-transporter	unknown	unknown	gnl|CDD|340911
NC_019693.1|WP_015146526.1|149959_150415_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146535.1|162137_162296_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146521.1|144179_144614_+|hypothetical-protein	unknown	unknown	gnl|CDD|223894

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015146530.1|155902_157051_-|cupin-like-domain-containing-protein	gnl|CDD|372651	pfam13621, Cupin_8, Cupin-like domain. This cupin like domain shares similarity to the JmjC domain.	3.13832e-44
NC_019693.1|WP_015146519.1|140337_140766_-|DUF2358-domain-containing-protein	gnl|CDD|370865	pfam10184, DUF2358, Uncharacterized conserved protein (DUF2358). DUF2358 is a family of conserved proteins found from plants to humans. The function is unknown.	5.15396e-50
NC_019693.1|WP_083896718.1|153584_154526_-|hypothetical-protein	gnl|CDD|226274	COG3751, EGL-9, Predicted proline hydroxylase [Posttranslational modification, protein turnover, chaperones].	2.6604e-31
NC_019693.1|WP_015146525.1|148289_149771_-|hypothetical-protein	gnl|CDD|225747	COG3206, GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane].	0.000212069
NC_019693.1|WP_015146520.1|141024_143952_+|excinuclease-ABC-subunit-UvrA	gnl|CDD|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NC_019693.1|WP_015146532.1|158303_159863_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl|CDD|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NC_019693.1|WP_015146527.1|150411_153399_-|tetratricopeptide-repeat-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	5.5551e-40
NC_019693.1|WP_015146529.1|154780_155659_-|hypothetical-protein	gnl|CDD|226274	COG3751, EGL-9, Predicted proline hydroxylase [Posttranslational modification, protein turnover, chaperones].	3.37825e-12
NC_019693.1|WP_015146537.1|163281_165144_+|molecular-chaperone-DnaK	gnl|CDD|184039	PRK13411, PRK13411, molecular chaperone DnaK; Provisional.	0
NC_019693.1|WP_015146538.1|165931_167062_+|molecular-chaperone-DnaJ	gnl|CDD|237663	PRK14293, PRK14293, molecular chaperone DnaJ.	0
NC_019693.1|WP_015146522.1|144676_145534_-|DUF1206-domain-containing-protein	gnl|CDD|377695	pfam06724, DUF1206, Domain of Unknown Function (DUF1206). This region consists of two a pair of transmembrane helices and occurs three times in each of the family member proteins.	9.40061e-16
NC_019693.1|WP_044196194.1|167124_167319_+|sulfurtransferase-TusA-family-protein	gnl|CDD|238180	cd00291, SirA_YedF_YeeD, SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA. A variety of microorganisms have similar proteins, all of which contain a common CPxP sequence motif in the N-terminal region. YhhP is suggested to be important for normal cell division and growth in rich nutrient medium. Moreover, despite a low primary sequence similarity, the YccP structure closely resembles the non-homologous C-terminal RNA-binding domain of E. coli translation initiation factor IF3. The signature CPxP motif serves to stabilize the N-terminal helix as part of the N-capping box and might be important in mRNA-binding.	4.93898e-13
NC_019693.1|WP_015146536.1|162332_163121_+|nucleotide-exchange-factor-GrpE	gnl|CDD|237624	PRK14143, PRK14143, heat shock protein GrpE; Provisional.	1.56134e-75
NC_019693.1|WP_015146524.1|147294_147987_-|Uma2-family-endonuclease	gnl|CDD|226983	COG4636, Uma2, Endonuclease, Uma2 family (restriction endonuclease fold) [General function prediction only].	4.16288e-16
NC_019693.1|WP_015146523.1|145932_147183_+|OFA-family-MFS-transporter	gnl|CDD|340911	cd17353, MFS_OFA_like, Oxalate:formate antiporter (OFA) and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of Oxalobacter formigenes oxalate:formate antiporter (OFA or OxlT) and similar proteins. O. formigenes, a commensal found in the gut of animals and humans, plays an important role in clearing dietary oxalate from the intestinal tract, which is carried out by OFA/OxlT, an anion transporter that facilitates the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation. This exchange generates an electrochemical proton gradient and is the source of energy for ATP synthesis in this cell. The OFA-like subfamily belongs to the Monocarboxylate transporter -like (MCT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.7627e-106
NC_019693.1|WP_015146531.1|157063_158137_-|cupin-like-domain-containing-protein	gnl|CDD|372651	pfam13621, Cupin_8, Cupin-like domain. This cupin like domain shares similarity to the JmjC domain.	3.09322e-53
NC_019693.1|WP_015146521.1|144179_144614_+|hypothetical-protein	gnl|CDD|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	1.42004e-17

Protein sequences

>NC_019693.1|WP_083896718.1|153584_154526_-|hypothetical-protein
MLKSNCYKVQRMTSNITETQTVHVMLLIAGGHQCELSMPADAPLLQDMLEAIALRSHPERSQPNKLFQIPMEDGGPTLYFPSRSIVAIATDPPVSLPDFSPEPEPIQPLQTATTPIIIESKSLKIQNFLSEEENQRILNYVIDNRGAFEDSQIGIDDPNYRRSKIFYYFHEFGDLIKERIKQILPQITEHLAIPTFEVSEIEAQITAHNDGHYYKAHNDNGDGVTATRTISYIYYFHREPKPFIGGELRMYDTLKLSDTLYSMAESYTDIPPTNNSIVFFASGCCHEVRPVNCPSKNFLDSRFTLNGWIRRTE
>NC_019693.1|WP_015146527.1|150411_153399_-|tetratricopeptide-repeat-protein
MWRKLWRWLKQIYHSLQQRFQKPEPPPPPRLIPDIERETKFMQTPVVEVEETGEVQEKDEAEELYQRGKEQFYRGNFTDALASWNEAIRLKRDYPDAYYLRGVAQGQLGQKEDAIASFNEAIHFKRDFPDAYYNRGVAQGQLGQNKDAIASFNEAICLKPNFPDAYYNRGVVQGQLGQKEDAIASFNEAICLKPNFSDAYYLRGLTQSQLGQYEDAIASFNEAIRLKPDFPDAYFHRGIVLCDHLKQYEDAIASFNEAIRFKSDFDTAYCNRGVAQRNLGQYEDAIASFNEAIRLKPDFSYAYFKRGVAQSKLRQYEDAIASFDSGLTLKRDAWQDWGNRGDAAGMLHRRNSPYLPSAFAILNPDLNERGFKGAMASYEEGLKYCPKDTHPEGWGMLHFDIANAYYNRSRKNPKTRYQDRQTAHTHYNLALETLTETAYPEAHLKVLRRLIRLLLGWNQTEQAQELKRRGTDVLRRLVEECTSPRKQRKLTLEFADFNQLTVDLWVQQGDVVQALEVAEAGKNACLSWLLDGRGDAVAEPSWQQIRKLLQGQTAVVYWHLSPYALTTFILKPDEDEPRVLRQSRFQDQSGYLGNLQELETWIEEWNQAYSRDKGNKTSAQSASWRKSLPQQLDRLSEILQISAILEELNHCQGYHRLILIPHKDLHRLPLHALFLNQDGFAESCAITYLPSAVFGLSLLDAAPSPEAQSLLSMGHEEPPQPPLAKGGLFSIGEEPPQPPLAKGGLFSSILSIENPKSLIKDRDGSHKPLAPLPAADIESEMISRLFPTSTRFAETEATTPAVKTALEQGHHVLHFTGHGYYEFADPVASALFLSGDDVLTVQDIIQLNLSSYHLIYLSACETAVTGNPTITSEYVGLTSGFLRSGVGSVLSTLWQVQSDASTLFALYFYQQLQQGHSYPVAFTATQKWLKSVTKADLSQWYQQQIEKLEQQPELSDGDIRCLNYFEGCRNGLAIIKENTPFSDPYHWSPFTLYGL
>NC_019693.1|WP_015146526.1|149959_150415_-|hypothetical-protein
MKDSDAIIVKAFLAALAQLSEPLPAHLQEELQTLSKTQKFTDLVLFARKHEPLKLAYQQANTQFTEQGNQYRKGLDILPDAYFEKASRDNSEIINVASDSSELNTLPKVLAKINERWPGQPDIQSVKQIFKSPNSVESAKTFLLYPEIPNF
>NC_019693.1|WP_015146525.1|148289_149771_-|hypothetical-protein
MNNNLQLIYPTLDIFLYDLGDGLGQSETKINENRLRFWQKIYPRLTQEELQPFAEVEGLATDSVELLQKKHGIEPFESPCDGYYYPVKLGDTYALQIDCSGEQKANPQISQPLEVIKTLDKVVLEHRHNPCTIGESWVLWGKLPTEQQDAEQTAEKCSHYLSLFADFQWDKDKDLKGSGEFAGATFYELWRLPSDRSPILDNRHLVICLFHSHTDITKIQQLYPHFRHLFQFRNKIIWAYQQSRQLKSDMKQAAQVIHRIVSDLPQQVTADSLNLKLLQKYLADTLTILSTYATYLSRLEEQQHTINSNLKNYQRRLKTFAKLDPENGDRLLNCFEPFADYALEKYQPQLESDIASLSAGLRLLENAIKTIEGIIQLEQTKSDRALSETVAIATVGLGLSAITATVVSTQQPPRGDRFFMVTPPFLWSIGILSPFILWLLLRLYRPLQGGKKGILPHPEGTPPSPPLLRGGVGFDVGDVRNSEKDALKNDIND
>NC_019693.1|WP_015146524.1|147294_147987_-|Uma2-family-endonuclease
MATTPQPKKVIYPDCDGNPMAENTRQFRWIVVIKENLEILFDNDPNIFIAGDLLWYPIEGNNKLRQAPDVMVAIGRPKGDRGSYKQWEEGNIPPQVVFEILSPGNRLNEMAKKQKFYERYGVEEYYIFDPDRFDFNGWIRNQAGSMDLIEQPENFTSPRLGIRFELQDEQFTIYRPDGDRFLTPTEIAKFAEQQRQEAEQQRQRAESAEARLRELEARLRELEGDRHPEG
>NC_019693.1|WP_015146523.1|145932_147183_+|OFA-family-MFS-transporter
MNITHDRSELTLFGLPAQQGRWLMIPLGMSVLLCLGSVYSWSVFRKPLEGELNIGATESLLPYTVALVFYAALMPIAGFYIPRIGTRIVTAIGGMIVGMGYILSSFANNIVAMTLTYGLIAGTGVGIAYGVPMAVVARWFPDKKGLAVGLTIIGFGLSPLITAPLAKGLIDAYSVRETLRILGIAFTLIILAIATTLKMPPKDWQPAQPLSAASCVVPSAYPGNILKSRSFYGLWICYSIGTFVGLSAIGISSPVGEEMIKIDPALAASSVSLFALFNGMSRPLFGWLSDRFKPRHVAMVSYTLVLIACLLMLSAQEGQVATYLIAFCLFWASLGGWLAMAPTTTLRLFNPDNYAQNYGIVFTAYGVGALLGTLIAGQIRDWFGSYTYAFYPMIFLAIVGMVVASLLLKRDPVSEV
>NC_019693.1|WP_015146522.1|144676_145534_-|DUF1206-domain-containing-protein
MTQSTQSTQSEWIERFARFGYAAKGFVYGLVGILALQVALNQGGQTTDPKGVLYEIVEQPFGQALLAFVTIGLIGYAMWRFLQAFMDTDNKGTDFKGLIERFGFGMSAVIYCGFAFTAIKILTGNGENGGEQSDQSAQHWTARFLSQPFGEWLVGLAGAVVIGLGFYYFYKAFTGKFRKELKIREMTPNEEKWVMRVGRVGLSARGIIFTMIGWFLMQAAYQSNANEAQAIPGTLETLLRQPYGSLLLGVVAAGLVIYGLYMGVHARYRRIHPPQGDPRQLLNQG
>NC_019693.1|WP_015146521.1|144179_144614_+|hypothetical-protein
MTLEQDTLLETALTFTVKPYDIDITGFVSQIIVMRWIEDLRLDLFQQYFSLEQQLELGISPLIGKTRLEYHKPIKLFDLIEGRMWFSDMGSVKWIVKTELMVDDKISVTAKQTGCFIHVASHRLVAIPDNLVKKFATYSSGGMS
>NC_019693.1|WP_015146520.1|141024_143952_+|excinuclease-ABC-subunit-UvrA
MPKRASASTKQPVQSLNGSSLTEAVVNPRDHGIRIRGARQHNLKNIDLELPRDRLIVFTGVSGSGKSSLAFDTIFAEGQRRYVESLSAYARQFLGQLDKPDVESIEGLSPAISIDQKSTSHNPRSTVGTVTEIYDYLRLLFGRAGKPHCPICDRSIAPQTIDEMCDRVMELPDRTKFQILAPVVRGKKGTHKKVLSSLSSEGFVRVRVNGEIRELSDKIELDKNHTHTIEIVVDRLIKKAGIQERLADSLTTGLRHSEGIAIIQLLDSTTDDGETELVFSEKFACPEHGAVMEELSPRLFSFNSPYGACESCHGLGSFRTFSPELIIPDSDAPIYEAIAPWADKESAYYLSVLQGLAKAYGFELTTPWNELTAKQQKSILYGADEPINIEGWGNNRRYAGALALLQRYYEESASELQKQKLDQYLVDRPCESCHGKRLKPEALAVRIGDEHIDDLTSVSIRDCRDRIDRLQLSSRQAQIAELVLREICARLQFLLDVGLDYLTLDRPAMTLSGGEAQRIRLATQIGAGLTGVLYVLDEPSIGLHQRDNGRLLHTLTKLRDLGNTLIVVEHDEDTIRAADWIVDIGPRAGVHGGEIVAQGQLDALLAAENSLTGSYLSGRLQIETPGERRKGNGRSLVMKNCSRNNLKQIDVEIPLGKLVCVTGVSGSGKSSLINDLLYPALQHHITRKTPFPGDMDALKTLGEKSLKDAVDKVIIIDQSPIGRTPRSNPATYTGVFDMIRGLFAETIEAKARGYKPGQFSFNVKGGRCEACGGQGVNVISMNFLPDVYVQCDICKGARYNRETLQVKYKGHSIADVLNLTVEEGLELFKHIPRAATRLQTLVDVGLGYIHLGQPAPTLSGGEAQRVKLATELSRRATGKTLYLIDEPTTGLSFYDVHQLLNVLQRLVDKGNSILTIEHNLDVIRCADWVIDLGPEGGDKGGEAIATGTPEEVAENSRSYTGEFLKRVLQQYPAQS
>NC_019693.1|WP_015146519.1|140337_140766_-|DUF2358-domain-containing-protein
MDEYQSQVFKAIATLKEDLPRLFEKDISYDIYRKDIFFKDPVNQFKWKFNYRIIFWTLRFHGQLFFTELYFDLHDVEQVEPDMILANWTVRGQLRLPWKADLFFNGYSNYKLDEDGLIYEHIDTWDREPKAILKQFLPRSET
>NC_019693.1|WP_015146529.1|154780_155659_-|hypothetical-protein
MESMELESNLVQVIVMMTGGHQYELSLMADAPLLQELFQALSNRGKNGGKDVFKIPNEEDGSCLYIPPDAIAAIATVPPIPIESLNLEPPSRQLEPSPPPPPPQKLIESSFVQLDNFLKPAEYQRLIETIFPQEGAASSGIQLPTPQSFALLREVLLHRVQMMLPDVLIQLGMGGFPLTEMEAQEIPTHAIEGQSISTDGNSPETALRVVNFCYFFYKTPKPFTGGELLVYDSQLLNNQVSVAQSYKTVEPRQNSIVFFLTSNAYEVLRVYPNSPAFRDRCFRVQGWMRRSG
>NC_019693.1|WP_015146530.1|155902_157051_-|cupin-like-domain-containing-protein
MNVDQLSGKMKTEKIEIEPAIATSEDSQLLQVMLLLEGGHQCEIALLPDAPLLRELFQGLTTAPESAESKLFQIPIEGGNAALYFPGESLVAIATDPPVAIESLDLEREEAEPDNPVQQLEWQLNIYRKLDKLSPNYGKIARIPHVSGAEFLERYYIGNKPVIFTDLMEKWPALYQWTPEYLKENYGHVTVGAQFNRNSNPAYEKQRRKHQKMLPLGEFVDIIRQGGETNDYYMGSYNGNLCRKPLQGLFNDIQLFPEYLTATPEPNRTVLWFGPAGAITPLHFDALNSFLCQVYGRKQVRLISPNHKHLLGNYGKYFSDIDLDHLDYERYPQLKEVDIIEVVLEAGEVLFLPVGWWHQVKSLDVSISISFMNFLVHNDFEE
>NC_019693.1|WP_015146531.1|157063_158137_-|cupin-like-domain-containing-protein
MQTDFWQAHLISPTQSGLSNDWKKWIAANKLRQLPDGQIVDILVQRGVDIRMAISEVKAVSANPCFQAACAMIAEEKQKLQDKSSLEATQIEKLELQLEVYRTLEKLSPHYNTIQRVDRLSQVDFLEKYYATNTPVILTDIMGNWPALSRWNPEYFKQHYGETTVEVQFNRESNPLFEQEKHKHRKQMTMGEYVDLVVNGGKTNDYYMVPYNENFDHSDLKQLLEEIEIFPEYLDPSNRTVCMFFWFGPEGTITPLHHDPCNVLLAQVYGKKRIRLISPNQKHLLYNQVGVYSEVDLLNPDYEKYPRFKDVEAIEVILEPGEVILLPVGWWHHVESLDIAISISFTNFLFPNFYNIK
>NC_019693.1|WP_015146532.1|158303_159863_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MARLALLSTSDKTGLIDLARHLVEEFGFDLISSGGTATALKAAGLQVTKVSDYTGSPEILGGRVKTLHPRIHGGILARRDLAEDRADLESNDIRPIDLVVVNLYPFEQTIAKEGVTFADAIENIDIGGPTLLRAAAKNHAHLTVLCNPGQYDSYLKELRSNGKASAEFRLSCARTAFWHTASYDRAIATYLDTAGNAEAQHPTLPDTFSISGHQIQSLRYGENPHQGAAWYQVGTTPTGWTAANKLQGKELSYNNLIDLEAARQIIAEFPGSSKDPAVAILKHTNPCGVAMGNSLVEAYQKALAADSVSAFGGIVACNRPLDAATATELTKTFLECVVAPDCEPEAVEILSKKSKVRILTLADLQTGPKKTIKPIAGGFLVQESDDAIAEPTEWKVVTEKQPTADQLAELLFAWKVVKHVKSNAIVVTGDRTTLGVGAGQMNRVGSVKIALEQAGEKAQGAVLASDGFFPFDDSVRTAAAAGIIAVVQPGGSLRDSDSIAAANELGLVMVCTGIRHFYH
>NC_019693.1|WP_015146534.1|160506_160950_-|hypothetical-protein
MKQLTPDSYPEQPVDDVVHSSDRILLAIVVTGLLYCFNIAWRHPGTPAQVADVLPATVELLSEVAADQVLQAVSTDSGLPKSALQIVESEPEVETEAICSGVAPDCSLTPPPSVQVKIASQEQLWVYRLNHSGSEVKVEKISSSRLE
>NC_019693.1|WP_015146535.1|162137_162296_-|hypothetical-protein
MTEGTGIPRAFQLQISAQPRLSHANSPVLATGLTIPRAVGEAKAIAPNRILD
>NC_019693.1|WP_015146536.1|162332_163121_+|nucleotide-exchange-factor-GrpE
MSKEAQVTEEQKQQEKTQTEWAAENTGGASNSADDTSEAAASDEWGHQGKVQEAPREAGVEESGPTETAEPTAAAPETPNASPEEFMAMEALVQANQAFTIQLEELKSQYARLAADFDNFRKRTQKEKLELEAQAKCATIRELLTVVDNFERAKEQIKPQNDGEMNLHKSYLSVYKQMVESLKRIGVSAMYPKGEEFDPNFHEAVMREPTREYAEGIVTDEFRRGYMLGDRVLRHAMVKVAAAPEDDDEEAIASETPDSPQE
>NC_019693.1|WP_015146537.1|163281_165144_+|molecular-chaperone-DnaK
MGKVIGIDLGTTNSCVAVLEGGKPNVISNTEGGRTTPSIVGIAKNGSRVVGQLAKRQAVTNAENTVYSIKRFIGRRWEDTEEERSRVPYTCIKGRDDTVDVKIRGTTYTPQEISAMILQKLKEDAEAYLSEEVTQAVITVPAYFTDAQRQATKDAGTIAGLEVLRIINEPTAAALSYGLDKQGQDQTILVFDLGGGTLDVSILQLGDGIFEVKSTSGNNHLGGDDFDTTLVKWMVEQFRINEGIDLSVDKMAVQRIREAAEKAKIELSSRESSAINLPFISADETGPKHLEMDLTREQFEELVSNLVKLSLEPVVQAIKDSTLSIEEIDRIILVGGSTRIPAVQKAISDYFGGKEPDRTVNPDEAVAIGAGIQAGVLGGEVQDVLLLDVTPLSLGIETLGGVFTKIIDRNTTIPTSRAQTFSTATDGQREVEIHVLQGERAMVKDNKSLGNFVLDKIPPAPRGVPQIEVSFEIDANGILNVAATDKGTERVQSIQITSTGGLSDEEIEKMRVDAEKYADEDRYRKQVAEIKNQAESLFYNYKATLKDNVALLSDELKAELKERGKQLKAALDNKTIEVEELKQRMSAFQETLFSVGIAVYQQSTPPEEEEEEKEEANTSE
>NC_019693.1|WP_015146538.1|165931_167062_+|molecular-chaperone-DnaJ
MARDYYEILGVARTADKEEIKRAYRRLARKYHPDVNKEEGAEERFKEINLAYEVLSEPEVRARYDRFGEAGVGSAAGGPGFGDMGDMGFADIFESFFSGFAGGGVPGQQGRRRSGPVRGDDLRLDLKLDFREAIFGGEKEIRISHLETCGVCVGTGAKPGTRPRTCPTCNGAGQVRRATRTPFGSFTQVSVCPTCNGTGETIEDKCEACNGAGVKQETKKLKINVPPGVDNGTRLRVSAEGDAGARGGPSGDLYVYLFVNEDAEFQRDNINILSEIKISYLQAILGCRLDVNTVDGPTELTIPAGTQPNTVMKLDSKGVPKLGNPAVRGDHLISVAIDIPTKLTAEERPLLEQLAKLKGDRTGKGGKGFLGDLFNK
>NC_019693.1|WP_044196194.1|167124_167319_+|sulfurtransferase-TusA-family-protein
MNFVRTKLRLDKMNPGEVLEVWLDPGEPIEQVPDSLVMDGHIMELIEDRGGFFALQVRRAAKSA

Crispr_ID: NC_019693_3

• CRISPR_ID: NC_019693_3
• CRISPR_location: 169842-169939
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_3

Consensus_repeat	Method
GGTCCGGGTTAGGGTGGGGTCCCCAAGT	CRISPRCasFinder

spacers of NC_019693_3

>3.1|169870|42|NC_019693|CRISPRCasFinder
CGAGACTAACCCAATCCACCTCCGGTCCCCTCCCCTTGGCAA

CRISPR arrays and Neighbor proteins around NC_019693_3

CRISPR arrays

The CRISPR arrays of NC_019693_3

>merge|NC_019693|3|169842-169939|CRISPRCasFinder
GGTCCGGGTTAGGGTGGGGTCCCCAAGTCGAGACTAACCCAATCCACCTCCGGTCCCCTCCCCTTGGCAAGGTCCGGGTTAGGGTGGGGTCCCCAAGT

>NC_019693|3|3|169842-169939|CRISPRCasFinder
GGTCCGGGTTAGGGTGGGGTCCCCAAGT	CGAGACTAACCCAATCCACCTCCGGTCCCCTCCCCTTGGCAA
GGTCCGGGTTAGGGTGGGGTCCCCAAGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015146535.1|162137_162296_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146547.1|176720_176969_-|UPF0175-family-protein	unknown	unknown	gnl|CDD|377095
NC_019693.1|WP_156824008.1|167429_168545_+|small-ribosomal-subunit-biogenesis-GTPase-RsgA	unknown	unknown	gnl|CDD|237040
NC_019693.1|WP_015146546.1|176130_176358_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146541.1|168674_168914_+|virulence-associated-protein	unknown	unknown	gnl|CDD|226863
NC_019693.1|WP_156823696.1|172851_176043_-|NACHT-domain-containing-protein	unknown	unknown	gnl|CDD|224331
NC_019693.1|WP_015146532.1|158303_159863_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl|CDD|234854
NC_019693.1|WP_015146543.1|170042_170600_+|SocA-family-protein	unknown	unknown	gnl|CDD|379096
NC_019693.1|WP_015146537.1|163281_165144_+|molecular-chaperone-DnaK	unknown	unknown	gnl|CDD|184039
NC_019693.1|WP_015146553.1|181079_182300_-|oxidoreductase-FAD-binding-domain-containing-protein	unknown	unknown	gnl|CDD|99804
NC_019693.1|WP_015146552.1|178528_180592_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_019693.1|WP_015146538.1|165931_167062_+|molecular-chaperone-DnaJ	unknown	unknown	gnl|CDD|237663
NC_019693.1|WP_015146536.1|162332_163121_+|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl|CDD|237624
NC_019693.1|WP_015146554.1|182977_183982_+|phosphoribulokinase	unknown	unknown	gnl|CDD|215198
NC_019693.1|WP_015146549.1|177713_177977_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|198034
NC_019693.1|WP_015146550.1|177963_178356_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350250
NC_019693.1|WP_044196194.1|167124_167319_+|sulfurtransferase-TusA-family-protein	unknown	unknown	gnl|CDD|238180
NC_019693.1|WP_015146544.1|170592_170985_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146534.1|160506_160950_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146542.1|168923_169328_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350315

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015146553.1|181079_182300_-|oxidoreductase-FAD-binding-domain-containing-protein	gnl|CDD|99804	cd06208, CYPOR_like_FNR, These ferredoxin reductases are related to the NADPH cytochrome p450 reductases (CYPOR), but lack the FAD-binding region connecting sub-domain. Ferredoxin-NADP+ reductase (FNR) is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins, such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently bound FAD as a prosthetic group) are present in chloroplasts, mitochondria, and bacteria in which they participate in a wide variety of redox metabolic pathways. The C-terminal domain contains most of the NADP(H) binding residues and the N-terminal domain interacts non-covalently with the isoalloxazine rings of the flavin molecule which lies largely in a large gap between the two domains. Ferredoxin-NADP+ reductase first accepts one electron from reduced ferredoxin to form a flavin semiquinone intermediate. The enzyme then accepts a second electron to form FADH2, which then transfers two electrons and a proton to NADP+ to form NADPH. CYPOR serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases, sulfite reducatase, and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via FAD and FMN. CYPOR has a C-terminal FNR-like FAD and NAD binding module, an FMN-binding domain, and an additional connecting domain (inserted within the FAD binding region) that orients the FNR and FMN -binding domains. The C-terminal domain contains most of the NADP(H) binding residues, and the N-terminal domain interacts non-covalently with the isoalloxazine rings of the flavin molecule, which lies largely in a large gap betweed the two domains. Ferredoxin-NADP+ reductase first accepts one electron from reduced ferredoxin to form a flavin semiquinone intermediate. The enzyme then accepts a second electron to form FADH2 which then transfers two electrons and a proton to NADP+ to form NADPH.	1.58242e-167
NC_019693.1|WP_015146547.1|176720_176969_-|UPF0175-family-protein	gnl|CDD|377095	pfam03683, UPF0175, Uncharacterized protein family (UPF0175). This family contains small proteins of unknown function.	9.07289e-22
NC_019693.1|WP_156824008.1|167429_168545_+|small-ribosomal-subunit-biogenesis-GTPase-RsgA	gnl|CDD|237040	PRK12289, PRK12289, small ribosomal subunit biogenesis GTPase RsgA.	0
NC_019693.1|WP_015146541.1|168674_168914_+|virulence-associated-protein	gnl|CDD|226863	COG4456, VagC, Virulence-associated protein and related proteins [Function unknown].	9.6482e-10
NC_019693.1|WP_156823696.1|172851_176043_-|NACHT-domain-containing-protein	gnl|CDD|224331	COG1413, COG1413, FOG: HEAT repeat [Energy production and conversion].	2.92881e-37
NC_019693.1|WP_015146532.1|158303_159863_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl|CDD|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NC_019693.1|WP_015146543.1|170042_170600_+|SocA-family-protein	gnl|CDD|379096	pfam13274, DUF4065, Protein of unknown function (DUF4065). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and viruses. Proteins in this family are typically between 155 and 202 amino acids in length.	1.12549e-25
NC_019693.1|WP_015146537.1|163281_165144_+|molecular-chaperone-DnaK	gnl|CDD|184039	PRK13411, PRK13411, molecular chaperone DnaK; Provisional.	0
NC_019693.1|WP_015146552.1|178528_180592_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.15122e-49
NC_019693.1|WP_015146538.1|165931_167062_+|molecular-chaperone-DnaJ	gnl|CDD|237663	PRK14293, PRK14293, molecular chaperone DnaJ.	0
NC_019693.1|WP_015146536.1|162332_163121_+|nucleotide-exchange-factor-GrpE	gnl|CDD|237624	PRK14143, PRK14143, heat shock protein GrpE; Provisional.	1.56134e-75
NC_019693.1|WP_015146554.1|182977_183982_+|phosphoribulokinase	gnl|CDD|215198	PLN02348, PLN02348, phosphoribulokinase.	0
NC_019693.1|WP_015146549.1|177713_177977_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl|CDD|198034	smart00966, SpoVT_AbrB, SpoVT / AbrB like domain. This domain is found in AbrB from Bacillus subtilis. The product of the abrB gene is an ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. AbrB is thought to interact directly with the transcription initiation regions of genes under its control. AbrB contains a helix-turn-helix structure, but this domain ends before the helix-turn-helix begins. The product of the B. subtilis gene spoVT is another member of this family and is also a transcriptional regulator. DNA-binding activity in this AbrB homologue requires hexamerisation. Another family member has been isolated from the Sulfolobus solfataricus and has been identified as a homologue of bacterial repressor-like proteins. The Escherichia coli family member SohA or Prl1F appears to be bifunctional and is able to regulate its own expression as well as relieve the export block imposed by high-level synthesis of beta-galactosidase hybrid proteins.	2.33497e-08
NC_019693.1|WP_015146550.1|177963_178356_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350250	cd18683, PIN_VapC-like, Uncharacterized subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	3.10971e-55
NC_019693.1|WP_044196194.1|167124_167319_+|sulfurtransferase-TusA-family-protein	gnl|CDD|238180	cd00291, SirA_YedF_YeeD, SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA. A variety of microorganisms have similar proteins, all of which contain a common CPxP sequence motif in the N-terminal region. YhhP is suggested to be important for normal cell division and growth in rich nutrient medium. Moreover, despite a low primary sequence similarity, the YccP structure closely resembles the non-homologous C-terminal RNA-binding domain of E. coli translation initiation factor IF3. The signature CPxP motif serves to stabilize the N-terminal helix as part of the N-capping box and might be important in mRNA-binding.	4.93898e-13
NC_019693.1|WP_015146542.1|168923_169328_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350315	cd18748, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily. The PIN_VapC4-5_FitB-like subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This subfamily belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.98678e-81

Protein sequences

>NC_019693.1|WP_015146542.1|168923_169328_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MTYQYLLDTNILSDLVRHPQGRIFQHIVDVGEDSVCTSIIVACELRFGVVKSGSSRLVQQLERILEVLTVLPLESPVDEHYASIRTNLEQAGTPIGPNDLLIAAHALALDLTLITANTREFERVPALKLDNWLR
>NC_019693.1|WP_015146541.1|168674_168914_+|virulence-associated-protein
MQNSRHVSLLTNGPDQVLTIPHELALSGTEVLLRKEGHRLIIEPIPANSLLSLLTTLPDITGDFPNIDEGLLPLDDIIL
>NC_019693.1|WP_156824008.1|167429_168545_+|small-ribosomal-subunit-biogenesis-GTPase-RsgA
MSPPGDRPELHSPVTPDESESRIIGTVVAVQANYYRVQLDRAVATASTLLCTRRSRLKKIGQQVMVGDRVVIEEPDWEGGRGAVAEVFPRQTELDRPAIANANQVLLVFAIEEPTLDPHQLTRFLVKAESAGLSVLLCLNKIDLVPEQERIEWQERLENWGYQPLFISVETGVGIDAVRDRLKDKITLISGPSGVGKSSLINQLIPFATLRVGDVSGKLGRGRHTTRHVELFDLPSGGLLADSPGFNQPNLDFPPRELAEYFPEARQRLQEGTCQFSDCLHRDEPNCVVSGDWERYDDYLEFLEEAIIYEEILSQQSNPESSMKVKSKGKGTEQNEPKLESKKYRRVSRRFQHQNLEQLYQDFEEEENQEF
>NC_019693.1|WP_044196194.1|167124_167319_+|sulfurtransferase-TusA-family-protein
MNFVRTKLRLDKMNPGEVLEVWLDPGEPIEQVPDSLVMDGHIMELIEDRGGFFALQVRRAAKSA
>NC_019693.1|WP_015146538.1|165931_167062_+|molecular-chaperone-DnaJ
MARDYYEILGVARTADKEEIKRAYRRLARKYHPDVNKEEGAEERFKEINLAYEVLSEPEVRARYDRFGEAGVGSAAGGPGFGDMGDMGFADIFESFFSGFAGGGVPGQQGRRRSGPVRGDDLRLDLKLDFREAIFGGEKEIRISHLETCGVCVGTGAKPGTRPRTCPTCNGAGQVRRATRTPFGSFTQVSVCPTCNGTGETIEDKCEACNGAGVKQETKKLKINVPPGVDNGTRLRVSAEGDAGARGGPSGDLYVYLFVNEDAEFQRDNINILSEIKISYLQAILGCRLDVNTVDGPTELTIPAGTQPNTVMKLDSKGVPKLGNPAVRGDHLISVAIDIPTKLTAEERPLLEQLAKLKGDRTGKGGKGFLGDLFNK
>NC_019693.1|WP_015146537.1|163281_165144_+|molecular-chaperone-DnaK
MGKVIGIDLGTTNSCVAVLEGGKPNVISNTEGGRTTPSIVGIAKNGSRVVGQLAKRQAVTNAENTVYSIKRFIGRRWEDTEEERSRVPYTCIKGRDDTVDVKIRGTTYTPQEISAMILQKLKEDAEAYLSEEVTQAVITVPAYFTDAQRQATKDAGTIAGLEVLRIINEPTAAALSYGLDKQGQDQTILVFDLGGGTLDVSILQLGDGIFEVKSTSGNNHLGGDDFDTTLVKWMVEQFRINEGIDLSVDKMAVQRIREAAEKAKIELSSRESSAINLPFISADETGPKHLEMDLTREQFEELVSNLVKLSLEPVVQAIKDSTLSIEEIDRIILVGGSTRIPAVQKAISDYFGGKEPDRTVNPDEAVAIGAGIQAGVLGGEVQDVLLLDVTPLSLGIETLGGVFTKIIDRNTTIPTSRAQTFSTATDGQREVEIHVLQGERAMVKDNKSLGNFVLDKIPPAPRGVPQIEVSFEIDANGILNVAATDKGTERVQSIQITSTGGLSDEEIEKMRVDAEKYADEDRYRKQVAEIKNQAESLFYNYKATLKDNVALLSDELKAELKERGKQLKAALDNKTIEVEELKQRMSAFQETLFSVGIAVYQQSTPPEEEEEEKEEANTSE
>NC_019693.1|WP_015146536.1|162332_163121_+|nucleotide-exchange-factor-GrpE
MSKEAQVTEEQKQQEKTQTEWAAENTGGASNSADDTSEAAASDEWGHQGKVQEAPREAGVEESGPTETAEPTAAAPETPNASPEEFMAMEALVQANQAFTIQLEELKSQYARLAADFDNFRKRTQKEKLELEAQAKCATIRELLTVVDNFERAKEQIKPQNDGEMNLHKSYLSVYKQMVESLKRIGVSAMYPKGEEFDPNFHEAVMREPTREYAEGIVTDEFRRGYMLGDRVLRHAMVKVAAAPEDDDEEAIASETPDSPQE
>NC_019693.1|WP_015146535.1|162137_162296_-|hypothetical-protein
MTEGTGIPRAFQLQISAQPRLSHANSPVLATGLTIPRAVGEAKAIAPNRILD
>NC_019693.1|WP_015146534.1|160506_160950_-|hypothetical-protein
MKQLTPDSYPEQPVDDVVHSSDRILLAIVVTGLLYCFNIAWRHPGTPAQVADVLPATVELLSEVAADQVLQAVSTDSGLPKSALQIVESEPEVETEAICSGVAPDCSLTPPPSVQVKIASQEQLWVYRLNHSGSEVKVEKISSSRLE
>NC_019693.1|WP_015146532.1|158303_159863_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MARLALLSTSDKTGLIDLARHLVEEFGFDLISSGGTATALKAAGLQVTKVSDYTGSPEILGGRVKTLHPRIHGGILARRDLAEDRADLESNDIRPIDLVVVNLYPFEQTIAKEGVTFADAIENIDIGGPTLLRAAAKNHAHLTVLCNPGQYDSYLKELRSNGKASAEFRLSCARTAFWHTASYDRAIATYLDTAGNAEAQHPTLPDTFSISGHQIQSLRYGENPHQGAAWYQVGTTPTGWTAANKLQGKELSYNNLIDLEAARQIIAEFPGSSKDPAVAILKHTNPCGVAMGNSLVEAYQKALAADSVSAFGGIVACNRPLDAATATELTKTFLECVVAPDCEPEAVEILSKKSKVRILTLADLQTGPKKTIKPIAGGFLVQESDDAIAEPTEWKVVTEKQPTADQLAELLFAWKVVKHVKSNAIVVTGDRTTLGVGAGQMNRVGSVKIALEQAGEKAQGAVLASDGFFPFDDSVRTAAAAGIIAVVQPGGSLRDSDSIAAANELGLVMVCTGIRHFYH
>NC_019693.1|WP_015146543.1|170042_170600_+|SocA-family-protein
MPIQFQFHPKKAVEAAAVLLKLHKKPMKYLGLVKMLYRADRLALERMDYPITGDNYLSMDYGPVLSRVYDLIKGKPIDNALPIWSEFISSPQDYGVELLKDPGNGELCAEEEDILQEVYKQFGELEPFRVAEWTDDLPEWQDPHGSAIPIPVEEILKNLGKSHEEITEIQQEAIREAYLDKVLND
>NC_019693.1|WP_015146544.1|170592_170985_+|hypothetical-protein
MTSITINLGDAFLLDTPPNGQHLYIAIAQTSETSYLFVNVTSYRASSEDACILEPGPGVPSFISRKSVIAYRFAREMNATQLAQLITPDSPIPKGSCSAVVLEQIQQGGLVSRRLPNKYKTALRAFLGIP
>NC_019693.1|WP_156823696.1|172851_176043_-|NACHT-domain-containing-protein
MTLFDPRRMPSAGELASMIGITLESPSSTKLGISTNAPIIKMGQKGKKNTVQAHQQGIQKLAEAKAAKRNYEGKVWTDLDIAGESGVSEKTVERFFGGQPVLLKTASTICTALGLEVKEVVDPNDWNPPTPTRDKPIPCQNAIAQFLEAIETQCQELRVFHTQQPIVLKHQYIPIEVTLKRRYRHQVETTWGYAESEEEQKRAYALKGMEEESRPVQVPWEKAKMEHQRMIVLADPGMGKSTLLKMEAVSQARQERQKLGQSQAIDRVVFPLFLRLSELQETNAEIIEAIPRLIQRDYPKHWREIEPFLRKKLELGQCLLLLDALDEVPREARNGLREKLSRFTESYRCPLIVTSRIVGYGGGFVTDAKEVEIVPFNPEQLQRYIQTWFVNAAGYIQDETVSASRLIEELKRKPQIQGLAQNPLLLSLICSLYQDKKLTLPTRRVQLYEQVVECMLKEWRGNREPQSDGKILAKLRFLETLAYQFSCQGQEIFTGDELYEAIKQGKNADSDLQNYPTEELMAELSEEDGIIQKLTRDGQNYLFLHRTFQEYFTAGYLNRVMARDPQQGMALVRAHFWEYDWHETLTLLAGLLKNPIPLLEAIAQEKDDIFGSLLLLAGRCLAECENLSHPVSEAICDRLYELWHRYPSLNFISSTVVTVGQNNLQMLQKLQNAALCDSDSDVRRQALEVLGKIGIPEAVPSLIDALCDSDSDIRRYAAITLEKSSTPETVTALIDALCDSDSDVRNNAAITLEKIGTLEVVTALIYALCNSDSDIRRYAALVLGNIGTLEVVTALIDVLSHSDSNVKIYAALVLGNMGTPEVVTALIDILSHSDSDVKIYAEWALEKIRTPEAVPALVPAPSHSDSDVRSDAVEVLGNIGILEAVPALIAALSHSNRDIRNKAASALAKIGTQEAVKALIATLSHSDSEVRIYAAWALGKIGTPEAVRALIATLSHCDSDVRYDVRYYAAWALGKIGTQEAVKALIATLSHSNRDVRSDAAEALKNLGTLDILKQIISSTTINVYEVEIIELVRILFIRYYQEKVPFFPLYPDVIGSKKQKNC
>NC_019693.1|WP_015146546.1|176130_176358_+|hypothetical-protein
MNNSEKTKAQRLSEAVSDFDTVLEQDPQVQLYRTQPSQTDVTGTAPPNLPPAFQVQWLLLLLVHLLVLLCGKNRG
>NC_019693.1|WP_015146547.1|176720_176969_-|UPF0175-family-protein
MTVIISDEILQASELTPSEFRQEVALHLFQTGRLTLGYASKLAEMPVAAFRQILKKRDIPLYSYDVEDFALDLKNLRELGRL
>NC_019693.1|WP_015146549.1|177713_177977_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MEISKVSETGQVIIPPEMRKTYSLEVGTEIILIDTGKGILIQPKQPFPPTTLNEVAGCLKYQGSPKTLEEMEAAISKGVQEQWHDSS
>NC_019693.1|WP_015146550.1|177963_178356_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MIPVDTNIVVRLLTQDDEVQYQKSLQIFQNPKIFIPDTVILETEWVLRFAYQFKPPQVCSALRKLLGLPNVYLTRSIVVHQALLWHETGLDFADAFHLAQSQDCEKFYTFDEKLIKKARGITNCEVKKPD
>NC_019693.1|WP_015146552.1|178528_180592_-|serine/threonine-protein-kinase
MMSNLPDFGEYGYQVIRELGHNRAGGRVTYLASRTGTSAPTPDVTPDPADLVAIKQFQFASTSDAGWAGYEAYQREIQVLQGLNHPGIPRYLDSFESPRGFCMVQEYKPAESLAQQRTWHPIQVKEIAVALLSILVYLQNRLPAVIHRDIKPENILVDQQMNVYLVDFGFAHIGEGEVAVSSIVKGTLGFMPPEQLFNRELTPASDLYGVGATLICLLTGTKSMEIGELIDPSYRIHFRKRVPTISLGWIQWLEKMVEPKPKDRYTNAETALEVLTPIEISRTPQVISSHQLVQFRGTKLGEPITQTISIKNPVPGTMLTGRWQVAPYRRDGYFSKNNHPWIKIEPVRFKGNQVECTITVDTRNLMADRIYERELLLQTNSDQKLYRFPLKVQTAPEPVEEIKLPYPWLGILLGLALNTGWTQPVNVVGDGIRWITASGLGMLVVLLLFSGILLFRIGAKSASRKPGPAAAGALAGSIIGVVTVPVSVIIYGNDDPSLSLSEIVEEAIGSAFWMAILGALIGAYAAIVTEELISRLRGMGTARDVSKTLAGAIAGVMFAVGPILDGSGSFSNAWAFLVWMGLIIVAGGVAGAVFDEIEQGKISPLSPNVKLKISQVWTNFAGRIVLLTVGLGISLGLALNGRILSHYWGILLIGGTAIPLWKMIYPHWVRSRQVREYHESKAKRIQP
>NC_019693.1|WP_015146553.1|181079_182300_-|oxidoreductase-FAD-binding-domain-containing-protein
MYNPSAAGVTVNTESGNRFFVYEVVGLRQTDESDATTNPIRRSGSTFITVPYNRMNQEMRRITRMGGQIVSIRPLGEEGTSNGHRTPTVSQEQTHKEAQPSKPMTETKAKKAKTDDIPVNIYKPKNPYIGKCLSNEPLVREGGSGIVQHLTFDLSAGDLRYLEGQSIGIIPPGEDQKGKPHKLRLYSIASTRHGDHEDDKTVSLCVRELVYQHPETNETVKGVCSSFLCHLQPGDDVAITGPVGKEMLLPDDEESTVIMMATGTGIAPFRAFLWRMFKEQHEDYKFKGLAWLFFGIPYSANILYKEELEKLQAEFPDNFRLTYAISREQENAQGGKMYIQDRIAENAEEIWNLLQKPNAHTYICGLKGMEGGIDEGMSAVTSKQGVDWLDYQKQLKKGHRWHVETY
>NC_019693.1|WP_015146554.1|182977_183982_+|phosphoribulokinase
MTSKPESVVLIGVAGDSGCGKSTFLHRLKDLFGEELMTVICLDDYHSLDRKQRKEHGVTALDPRANNFDLMYEQVKALKNGQGVNKPIYNHETGMIDPPERVEPNHIIVIEGLHPIYDERVRSLLDFSVYLDISDEVKIAWKIQRDMAERGHRYEDVLASINSRRPDFSAYIEPQKAHADVVIRVLPTNLIPDDKERKVLRVQMIQRYGVHGMDPVYLFDEGSTINWTPCGRKLTCSYPGIKMAYGPDAFEGHEVSILEVDGQFENLEEMIYIESHLSNTSTKFYGELTELLLQHPTYPGSNNGTGLFQVLTGLKMRAAYERLTSKEAKIAAKV

Crispr_ID: NC_019693_4

• CRISPR_ID: NC_019693_4
• CRISPR_location: 222716-222813
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_4

Consensus_repeat	Method
TTAGGGTGGGGTTCTTCTTGGGCGATCGCACCTC	CRISPRCasFinder

spacers of NC_019693_4

>4.1|222750|30|NC_019693|CRISPRCasFinder
CGGTCCCCTCCCCTTAGCAAGGGGAGGGTT

CRISPR arrays and Neighbor proteins around NC_019693_4

CRISPR arrays

The CRISPR arrays of NC_019693_4

>merge|NC_019693|4|222716-222813|CRISPRCasFinder
TTAGGGTGGGGTTCTTCTTGGGCGATCGCACCTCCGGTCCCCTCCCCTTAGCAAGGGGAGGGTTTAGGGTGGGGTTCTTCATTGGGCGATCGCACCTC

>NC_019693|4|4|222716-222813|CRISPRCasFinder
TTAGGGTGGGGTTCTTCTTGGGCGATCGCACCTC	CGGTCCCCTCCCCTTAGCAAGGGGAGGGTT
TAGGGTGGGGTTCTTCATTGGGCGATCGCACCTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015146599.1|236934_237705_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_019693.1|WP_015146580.1|213144_213420_-|UPF0175-family-protein	unknown	unknown	gnl|CDD|377095
NC_019693.1|WP_015146596.1|232583_233120_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_019693.1|WP_015146583.1|214499_214835_+|DUF86-domain-containing-protein	unknown	unknown	gnl|CDD|225236
NC_019693.1|WP_015146586.1|216324_216573_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146582.1|214195_214528_+|nucleotidyltransferase-family-protein	unknown	unknown	gnl|CDD|224583
NC_019693.1|WP_015146585.1|215912_216335_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|225266
NC_019693.1|WP_156823699.1|230160_230298_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146592.1|224501_224789_+|DUF2470-domain-containing-protein	unknown	unknown	gnl|CDD|378456
NC_019693.1|WP_015146593.1|225259_228172_+|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|274362
NC_019693.1|WP_015146598.1|234795_236685_-|WD40-repeat-containing-protein	unknown	unknown	gnl|CDD|238121
NC_019693.1|WP_015146584.1|215472_215685_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146581.1|213444_213726_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146587.1|216926_220910_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NC_019693.1|WP_015146589.1|221254_222658_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823698.1|220881_221274_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146594.1|230446_231829_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl|CDD|235392
NC_019693.1|WP_015146595.1|232002_232572_+|DUF2062-domain-containing-protein	unknown	unknown	gnl|CDD|378263
NC_019693.1|WP_015146590.1|223014_224262_+|hypothetical-protein	unknown	unknown	gnl|CDD|99740
NC_019693.1|WP_083896723.1|233186_234851_-|hypothetical-protein	unknown	unknown	gnl|CDD|238121

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015146599.1|236934_237705_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.34759e-22
NC_019693.1|WP_015146580.1|213144_213420_-|UPF0175-family-protein	gnl|CDD|377095	pfam03683, UPF0175, Uncharacterized protein family (UPF0175). This family contains small proteins of unknown function.	3.01673e-18
NC_019693.1|WP_015146596.1|232583_233120_-|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	2.54996e-42
NC_019693.1|WP_015146583.1|214499_214835_+|DUF86-domain-containing-protein	gnl|CDD|225236	COG2361, COG2361, Uncharacterized conserved protein [Function unknown].	1.80076e-29
NC_019693.1|WP_015146582.1|214195_214528_+|nucleotidyltransferase-family-protein	gnl|CDD|224583	COG1669, COG1669, Predicted nucleotidyltransferases [General function prediction only].	6.66471e-23
NC_019693.1|WP_015146585.1|215912_216335_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|225266	COG2402, COG2402, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	2.78244e-22
NC_019693.1|WP_015146595.1|232002_232572_+|DUF2062-domain-containing-protein	gnl|CDD|378263	pfam09835, DUF2062, Uncharacterized protein conserved in bacteria (DUF2062). This domain, found in various prokaryotic proteins, has no known function.	9.5281e-43
NC_019693.1|WP_015146592.1|224501_224789_+|DUF2470-domain-containing-protein	gnl|CDD|378456	pfam10615, DUF2470, Protein of unknown function (DUF2470). This family is a putative haem-iron utilisation family, as many members are annotated as being pyridoxamine 5'-phosphate oxidase-related, FMN-binding; however this could not be confirmed.	2.43177e-27
NC_019693.1|WP_015146593.1|225259_228172_+|SpoIIE-family-protein-phosphatase	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	4.10239e-69
NC_019693.1|WP_015146598.1|234795_236685_-|WD40-repeat-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	8.18024e-69
NC_019693.1|WP_015146594.1|230446_231829_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl|CDD|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NC_019693.1|WP_015146587.1|216926_220910_+|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	7.23733e-45
NC_019693.1|WP_015146590.1|223014_224262_+|hypothetical-protein	gnl|CDD|99740	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.	5.11312e-33
NC_019693.1|WP_083896723.1|233186_234851_-|hypothetical-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	1.1966e-47

Protein sequences

>NC_019693.1|WP_015146589.1|221254_222658_+|hypothetical-protein
MKNLNLSLYAFHLCQSLDDAPDTHSKDAGLLWDSLRGLAAKIPFPELKKITEPTEANPETSLDFQAIEINHISLTGNLSTFKIHDTYSVDLTLSFQDKQAHFFPGNVVIFQPQALIDVTANLGKVLWLSGESEDVNELQLTRATQWAEQLCQQATYIEEDHLFNSPLFIFAADSVTILISLAEPNAIDLERAQENYYNLRNLFWTYQKIVVVEKLAKEGYQGARKLYSELEAQVQEFNQVFLQTPEERLKKLDELLQTIPQRLLDYNCKLRDLKANYTTIDVNWKNFKVSLSHILDESAGDKLSYWSDFATKTAPLYLTQIKTYIDYLEPGQVLFSDLINSIRATAEIEQVKSDRQRQQAEKDYYQQQQDDNQKLQNRIQAVGVGIAAGAIFASTAGSINEPWLFPNGQKMEVPFLPPHPFLLGLLGSIICSVGAWWLAETFINPGKNKSDKSSNQLAKNQQNPKSN
>NC_019693.1|WP_156823698.1|220881_221274_+|hypothetical-protein
MDRENKTMVSHAKKIAAFTALLQENLNNWIANHGESLLALQQQLDDDDEKNAQAIESWLKEREDLYKQYEAKLARPKRTLSLSGEKGFAGIKAPGKDKSLAEQIEQAVKNNTNLETSAPSPEQDREKPQS
>NC_019693.1|WP_015146587.1|216926_220910_+|CHAT-domain-containing-protein
MDEQRVQAYLALIQELLECPSGEEPQILSQSSELVDEGFVQVCELVAAQLQEEGQDNQAQFLRDVAQEVGQYLNSQTSAVATGEGPTQGTEQDYLNFLIEVLGAIEQSQGNPQVVYPLLQQNLDKLDLTLAETLQHLASQVFGQVESNQTYGIAGSIFLLSNLIQQFPLGNRADNLEIAIASYQSVLKVFTREVYPEDWAGVQNNLGITYYNRIREDRGQNIEKSILCYQAALDVFTRPAFPLKWAMAQNNLGEAYLFQVKGDRSENIEKAITYYEYALEVCTRHTFSKQWAMIQTNLGNAYFFRIRGKREENIEKSIRYCKAALEVCTQETLPYEWARSQNTLGNSYLFRIRGERANNIELAITALELALKVRKRESFPLDWAMSQNNLGNAYLFRINGNKADNIEQAIFSIEVALELCTNQTLPYEWARGHSSLGNAYLFRIRGERLDNIERSIRASEFALQVYTHESFPEEWATTQNNLGNAYLYRIQGERAENLERAITFMKASLEVYTHEGFPEQWATTQNNLGVAYLSRIRGERAENLERAITFMQTSLEVYTREGFPEQWARTQNNLGETYRNRIRGERAENLEISIAFLEASLQVYTRQAFPYEWARTQNNLGVVYQTRIQGERVENLDRAIAFLEASLQVYTREAFPEDWARTQNNLGSTYQARIRGERAENLERAISYLESSLQVYTREGFPYEWATTQVNLGGTYRNRIRGERAENLDRAIVCSEAALEIYTRTDFPQEHTKTLGILGLAYQAQSHYYSNDPIKKRTALQNAYIVLEQALDTVEYLRGEITSGDEAKRKLNEEWMGLYVLMVEVCLELGKYTAAIEYVDRSKARNLTELIATRDAYPRGDIPPEVRQRLQQLRQAISEEDRCLKQDPNPDYTHISQLREEFQANYPYKPLKFPDIQSLLDDETVILEWYILDEKFLTFTLTNQTLNLWASSEEDRQNLIDWTVAYIDDYDNNSQWRDSLPQRLETLAQILHLDEILQNLRQNFPNCQKLILIPHLFLHLFPLHALPIPVIATDGVRAQCLRPISGPNGHQEGLHIAPLQDIFPKGVTYAPNCQLLQQAQNRQRPHFNQLFAIQNPTEDLDWADVEIENIRTLFPEPETLAWEDATTANLLDEQRREILSQTHHLFFSCHAAFNPNSPLDSGLLLADGILTLENIIANLNLSNCSLVTLSACETGQVAIDTTDEYISLSSGFILAGSPSVLVSLWSVNQVSTALLLIRTYELLQQQPGQLAQSLQAAQKWLRETTVSGFEQWRQQCPLFSEEWREALQPVFAQMGQNKEEGINHRPYQSPYHWAAFCIVGQGEQNNG
>NC_019693.1|WP_015146586.1|216324_216573_-|hypothetical-protein
MTRKINLELSDDLSQRLESKAQIINLSLEAMILKSLEDLATQPDDPIAALIGTLSAENNDIASRHDDYIGEAIYSRELSSEK
>NC_019693.1|WP_015146585.1|215912_216335_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MKNSVFVDTSGWANLFIKTEPDHPYAVEWFTQARQQKYLMVTSNYIVLELVALLNSPLRVPRPQIFQYIDAIHSAPYLQLVRVNQQIENAAWELLKKRLDKTWSLVDATSFIIMQQLEITNALTSDHHFDQAGFVRLLKS
>NC_019693.1|WP_015146584.1|215472_215685_-|hypothetical-protein
MTGQPTENQPQAIEARVTSLEIELTQIKEVLATVTSPQQPWWERIAGSHANDPTFESVIQLGQEWRKTAE
>NC_019693.1|WP_015146583.1|214499_214835_+|DUF86-domain-containing-protein
MERDVQSLLDMLQSAEIVMDYISGRSRNDLATDLQLQDAIIRRLLIIGEAAKRVSEPTRNRLTTIPWSVINGMRNRLVHEYDGIDLDVVWDTAVKSLPRLILELKKVIPTP
>NC_019693.1|WP_015146582.1|214195_214528_+|nucleotidyltransferase-family-protein
MIQTAIALPMEKIAEFCQKWKVTELALFGSILRDDFNGNSDVDVMVQFHPEAHPTLFDLAEMEEELKQLFQRDVDLITRKGIETSRNYLRRQAILSSAQVIYGTGCSIVA
>NC_019693.1|WP_015146581.1|213444_213726_-|hypothetical-protein
MGTMDNSPIQDTESAAPMSVTELQSQLNDLLKQLSPERLRVLADFAAYLANAESETATQELLEIPGLLERVKQNQATPKNQYRSWRTLSKPLN
>NC_019693.1|WP_015146580.1|213144_213420_-|UPF0175-family-protein
MQITIEIPDEYIQQLQPNLDNFSERILETLVIEAYQSQHITAAEVGQILNLDRFAVDDFLKQKGAYYHYTIADFDQDLQTINTLHNQSNIR
>NC_019693.1|WP_015146590.1|223014_224262_+|hypothetical-protein
MWSRKRFDIDYIDLIYGLGAALTVENSQRQGLQNDLEDWWGQDSTGETVACLSVRSGWDLLLQALQLPPGSEVAMSALTIPDMVTIVRAHGLVPVPIDLDPETMAPDPASLDRATGPRTRVIIIAHLFGGRVDLAPILAARDRVGAILVEDCAQAFTPGFRGHPEADVSCFSFGTIKFATALGGALLRVRDPQLADCLRQIQSTYPVQDSGNYTRRLLKYLGLKTLSSRPGFTALIWGCRRWGIDYDRLLNQSVKGFPKDELIWRLRHQPCAPLLALLRHRLQGYTEQRLAEQTHRGQRLIQLLQEYCPQIQVPGVATSPNMHWIVPILAEDPKLAIATLVNAGFDATQGHSMTVVDSPATHPEGEPRNTRELFQHLLYLPCYPAMDDQVLVSMAQALRPISFPLVSAFSRMGSA
>NC_019693.1|WP_015146592.1|224501_224789_+|DUF2470-domain-containing-protein
MADLISAQVSDRICKHMNDDHADSVLLYAQIFGEVTDATSATLLAIDPLGMNLTAQVGEKSLPVRVTFDHALADSEDAHHTLIAMVKQARQLKTA
>NC_019693.1|WP_015146593.1|225259_228172_+|SpoIIE-family-protein-phosphatase
MTSNSGIKVSWSLTKSETTLIQILFVAVSYFLISEFGAVFLALKEGGSPVWPGSGVALAGVLLLGYPMGIAVVLGNVLVNFFLTEWSIADMVMNFNFTLGNTLETLSAAYFIHKFSVNFKWFSRVKDVIYFVIFAGLISPMFSATFGAGTIWLLGRIPWDVVPGLWVTWWIGDVVGILVFAPVLLVFGQGINEFFQKSQQRWMEGLVFVFITLVTCQMAFLKGYPVEYMLLPLLVWTVFRFGQWSATLLLLIGSVLAILATANDLGPFIRSNLNESLILLQSFVGVFSLTTLTLSAVICENEQAQQRLETANIQLQHLDRLKDEFLANTSHELRTPLNGIIGIAESLIDGATGELPVPTRANLAMISSSGRRLSNLVNDLLDFSKLKHKTLELQLKPIDLRSLAEIVFTLSLPLVGDKNLNLVNNISLDLPAVTADENRLQQILHNLIGNAIKFTETGTIEISAQRIFGDESLEPLSSVSQVEITIADTGIGIAEDKLERIFESFEQAEGSTGRMYGGTGVGLAIAKQLVELHGGQIWVNSRLGEGSKFSFTLPLSGEKIENSSETLPLLKQFATADLNPEPLEPRVIASHKGSAKLLIVDDEPINLQVLVNMLSLQNYTVIQAKNGLDALELLHKGFKPDLVLLDVMMPKMTGYEVTQKIRETWQASEMPVLLLTAKNQLSDLVAGFESGANDYLTKPVEKDELLARIKTHLNLLRLKNENLRLVAELEVTRQQQQMLLPSTEELELIEDLEIAAFMEPATEVGGDYYDVIQHQWGVKIGIGDVTGHGLESGVLMIMVQMAVRTLLESDIRNPVHFLTLLNLAVYGNLQRMKSEKNMSLMLLDYHQGKLVVSGQHEDIILVRAGGQVKLIDTVDLGFPVGLVEDIGEFVAEMVIELNPGDVAIVYTDGITEAENMEGVQYGLQRMMELAGQQQGRSATEIVDVILADVREFIGKQKVYDDITLLVLKQK
>NC_019693.1|WP_156823699.1|230160_230298_+|hypothetical-protein
MGSSGWRSHLTMNGWVEGSPDVAIARYEERVFSSLHTGAIVSTSA
>NC_019693.1|WP_015146594.1|230446_231829_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MDRVTQRETIAAIATAIVPQQGSIGIVRLSGSQALAIAQTLFHAPGSQPWETHRILYGTIRHPKTQQIVDEALLLLMKSPRSFTREDVVEFHCHGGIIPVQQVLQLCLELGARLAQPGEFTLRAFLNGRLDLTQAESVADLVGAQSPAASQAALAGLQGKLAHPIRQLRTQCLDILAEIEARIDFEEDLPPLNEPEIIQSIQSIIQEVEKILGTANQGELLRMGLKVAIVGRPNVGKSSLLNAWSRSDRAIVTNLPGTTRDVVESQLVVQGIPVQVLDTAGIRATEDTVEKIGVERSRLAAQSADLVLLTLDAQAGWTADDYEIYQQVNHKPIVVIFNKIDLVEQIPLLPNLDNIRETVNTSAAHQQGIEALETAILNTVHAGNLQAENLDFAINQRQAAALTRAQTALEQVQTTIDQQLPLDFWTIDLRGAIQALGEITGEEVTESVLDRIFSRFCIGK
>NC_019693.1|WP_015146595.1|232002_232572_+|DUF2062-domain-containing-protein
MLHKHPLPINSRRTQIKRVRSASLFSKRQRSRSRWQRFWRYYYWRLVRQKGSPEFLARGLAAGVFAGLFPLFGLQTILGVALAILFRGNKWMAVAGTWVSNPLTYGPIFWLNFEVGQWLLKSHEVFELERIQSTKALLEVGADFLIILFVGCLVMASFSAFLSYFLGLKLIRRWRTLNRGWRRRHHAGR
>NC_019693.1|WP_015146596.1|232583_233120_-|Uma2-family-endonuclease
MTPEDYFAGEEISPIRREYIRGEVYAMSASTPVHNMITLNLATLIRKQVRGTECYAFVQDIKIRIETADVFYYPDLTVTCDPRDQQFTDSFIRYPCLIVEVLSESTEAFDRGDKFADYRQIETLKEYLVISQTRPSVECFRRNHSGRWELYSYQGQEQIRLTSLNLVIDMATLYEDVW
>NC_019693.1|WP_083896723.1|233186_234851_-|hypothetical-protein
MVKRWWVGVGILKFGGCLEGRMNHRLHRFSPMAGMIAAMAIVAGGLGPVSFSGRFEGWELQALASESPLFNPPLAIGEVTATAKDITVFISGPISGSGAIVHRQGNVYTVLTTKTVVSGRGVYEVVTGDGRRYSVSPEGVILLPLVDLAVLQFTSSETYPVAQLAEPSDSQIYLTVANQPQTTLFAAGNLVSTAGTNLSDGYDLLYNSALQSAGSGGPVVDRWGRLIGIQGRFNTQSPTVNSAIAVSNFLRLAPTVGLNLGWRGWILSNIIQPGSKPRAIALSSDGTLLATDGGYNRIQLWDWQSSQLNATLTGHNSEVNSLAISPNKQILVSGDQQGQAIIWNLRTGQIANTITRSRPNLSNPITSVAITANGQTLITGSNQGIELWEINTGRLVLTLPESGEANAIAISPDSRTLVSGHLDNTVKVWNLLNGNLVQTLPAGERGFIVESVAISPDGNTIAAGTYREIRLWNLERGIRQRTIVAHCDLCYVYDLAFTRDGTGIISTSEDGTKIWNIADGTLLRTLDGSAKTFALSGDRTLILGGDTLRIWQVP
>NC_019693.1|WP_015146598.1|234795_236685_-|WD40-repeat-containing-protein
MKGWQKFQGPRLFRALGVALGETPVTPRLRPRDPIRVLTVVFGLMLPVGMMESAEAQSTYTDITNHWARTCIETLAERDILAVFSSETFRPEDPIQRVEFASVVRKAFPNVEPVRDPIEFIDLPTDYWGREIVQDAYRSGFISPYSGRAFNPTQVIPRWQAIALLTTGLRYKSPENGLEMVEASLADWEGIPDYARGAIAAGIQNRLVVNYPDPRTLNPTEPLSRGELASMICQVQEDIGAIALVPQQYVASPDAIATAETPTAETPTAETPTAETPTVETPTAETPTAETPTPPTPIAAGNQRWQTAVLTNVLNFQPTGITPDSQVEQCVTDTSGTPRCESISASMDATAIAIDGQGFVMASGHRGADLAPINLWDLRTGDRIRTLEGHRGRVGALAIAPNGQWALSGGGDGEIKIWDIRTGTLTQTLTGHTNEVTGLEIASNGNTAISSSRDRTVKLWDLNTGEVLRTLEDRQTAMLDVAVSSDGRMAASSSEDGLVRLWNLQSGELIRTISADINAVRTLAFSPNGQTLATGGEGTIRLWNIANGDLVRTIARNPEATFFEVAFSNDGETLVGTVQEGDISAIRIWDVRTGALLHFFPTAAAAIALTPDGQTLVGGGWDIKIWRMP
>NC_019693.1|WP_015146599.1|236934_237705_-|class-I-SAM-dependent-methyltransferase
MLNSQSSVPKIIIPDELLPPKELRLSVGGSFKAIGTEFFRYFIEIAGLQPDEAVLDVGCGVGRMAVPLTQYLSDRGRYEGFDIVESAITWCQSVISPRYPNFQFQRADLYNQYYNPTGQAQANTYRFPYSDNHFDFVFLTSVFTHILPDGIENYLREISRVLKPGGRALITAFLLNKDSLYCLESGLSALEFTEIFENYRLADKIFPESAVAYEEQFFITLAEQVGLRVNSPIYYGCWCGREDFLSFQDILLMGKS

Crispr_ID: NC_019693_5

• CRISPR_ID: NC_019693_5
• CRISPR_location: 230315-230407
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_5

Consensus_repeat	Method
GAAGAACCCCACCCTAACCCTCCCCT	CRISPRCasFinder

spacers of NC_019693_5

>5.1|230341|41|NC_019693|CRISPRCasFinder
TGCCAAGGGGAGGGGACCGGAGGTGCTGTTAAACCAGGTCC

CRISPR arrays and Neighbor proteins around NC_019693_5

CRISPR arrays

The CRISPR arrays of NC_019693_5

>merge|NC_019693|5|230315-230407|CRISPRCasFinder
GAAGAACCCCACCCTAACCCTCCCCTTGCCAAGGGGAGGGGACCGGAGGTGCTGTTAAACCAGGTCCGAAGAACCCCACCCTAACCCTCCCCT

>NC_019693|5|5|230315-230407|CRISPRCasFinder
GAAGAACCCCACCCTAACCCTCCCCT	TGCCAAGGGGAGGGGACCGGAGGTGCTGTTAAACCAGGTCC
GAAGAACCCCACCCTAACCCTCCCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015146599.1|236934_237705_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_019693.1|WP_156823699.1|230160_230298_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146596.1|232583_233120_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_019693.1|WP_015146600.1|238088_239405_-|homoserine-dehydrogenase	unknown	unknown	gnl|CDD|235783
NC_019693.1|WP_015146586.1|216324_216573_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146602.1|240038_240275_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl|CDD|376852
NC_019693.1|WP_015146585.1|215912_216335_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|225266
NC_019693.1|WP_015146594.1|230446_231829_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl|CDD|235392
NC_019693.1|WP_015146592.1|224501_224789_+|DUF2470-domain-containing-protein	unknown	unknown	gnl|CDD|378456
NC_019693.1|WP_015146593.1|225259_228172_+|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|274362
NC_019693.1|WP_015146598.1|234795_236685_-|WD40-repeat-containing-protein	unknown	unknown	gnl|CDD|238121
NC_019693.1|WP_015146584.1|215472_215685_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044196223.1|240340_241105_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NC_019693.1|WP_015146587.1|216926_220910_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NC_019693.1|WP_015146589.1|221254_222658_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146590.1|223014_224262_+|hypothetical-protein	unknown	unknown	gnl|CDD|99740
NC_019693.1|WP_015146601.1|239674_240052_-|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350220
NC_019693.1|WP_015146595.1|232002_232572_+|DUF2062-domain-containing-protein	unknown	unknown	gnl|CDD|378263
NC_019693.1|WP_156823698.1|220881_221274_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_083896723.1|233186_234851_-|hypothetical-protein	unknown	unknown	gnl|CDD|238121

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015146599.1|236934_237705_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.34759e-22
NC_019693.1|WP_015146596.1|232583_233120_-|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	2.54996e-42
NC_019693.1|WP_015146600.1|238088_239405_-|homoserine-dehydrogenase	gnl|CDD|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	0
NC_019693.1|WP_015146585.1|215912_216335_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|225266	COG2402, COG2402, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	2.78244e-22
NC_019693.1|WP_015146595.1|232002_232572_+|DUF2062-domain-containing-protein	gnl|CDD|378263	pfam09835, DUF2062, Uncharacterized protein conserved in bacteria (DUF2062). This domain, found in various prokaryotic proteins, has no known function.	9.5281e-43
NC_019693.1|WP_015146592.1|224501_224789_+|DUF2470-domain-containing-protein	gnl|CDD|378456	pfam10615, DUF2470, Protein of unknown function (DUF2470). This family is a putative haem-iron utilisation family, as many members are annotated as being pyridoxamine 5'-phosphate oxidase-related, FMN-binding; however this could not be confirmed.	2.43177e-27
NC_019693.1|WP_015146593.1|225259_228172_+|SpoIIE-family-protein-phosphatase	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	4.10239e-69
NC_019693.1|WP_015146598.1|234795_236685_-|WD40-repeat-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	8.18024e-69
NC_019693.1|WP_015146594.1|230446_231829_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl|CDD|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NC_019693.1|WP_044196223.1|240340_241105_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	3.12364e-33
NC_019693.1|WP_015146587.1|216926_220910_+|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	7.23733e-45
NC_019693.1|WP_015146590.1|223014_224262_+|hypothetical-protein	gnl|CDD|99740	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.	5.11312e-33
NC_019693.1|WP_015146601.1|239674_240052_-|PIN-domain-containing-protein	gnl|CDD|350220	cd09872, PIN_Sll0205-like, VapC-like PIN domain of Sll0205 protein and homologs. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of the Synechocystis sp. (strain PCC 6803) Sll0205 protein and other uncharacterized homologs are included in this subfamily. They are similar to the PIN domains of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.06465e-14
NC_019693.1|WP_015146602.1|240038_240275_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl|CDD|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	0.000314582
NC_019693.1|WP_083896723.1|233186_234851_-|hypothetical-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	1.1966e-47

Protein sequences

>NC_019693.1|WP_156823699.1|230160_230298_+|hypothetical-protein
MGSSGWRSHLTMNGWVEGSPDVAIARYEERVFSSLHTGAIVSTSA
>NC_019693.1|WP_015146593.1|225259_228172_+|SpoIIE-family-protein-phosphatase
MTSNSGIKVSWSLTKSETTLIQILFVAVSYFLISEFGAVFLALKEGGSPVWPGSGVALAGVLLLGYPMGIAVVLGNVLVNFFLTEWSIADMVMNFNFTLGNTLETLSAAYFIHKFSVNFKWFSRVKDVIYFVIFAGLISPMFSATFGAGTIWLLGRIPWDVVPGLWVTWWIGDVVGILVFAPVLLVFGQGINEFFQKSQQRWMEGLVFVFITLVTCQMAFLKGYPVEYMLLPLLVWTVFRFGQWSATLLLLIGSVLAILATANDLGPFIRSNLNESLILLQSFVGVFSLTTLTLSAVICENEQAQQRLETANIQLQHLDRLKDEFLANTSHELRTPLNGIIGIAESLIDGATGELPVPTRANLAMISSSGRRLSNLVNDLLDFSKLKHKTLELQLKPIDLRSLAEIVFTLSLPLVGDKNLNLVNNISLDLPAVTADENRLQQILHNLIGNAIKFTETGTIEISAQRIFGDESLEPLSSVSQVEITIADTGIGIAEDKLERIFESFEQAEGSTGRMYGGTGVGLAIAKQLVELHGGQIWVNSRLGEGSKFSFTLPLSGEKIENSSETLPLLKQFATADLNPEPLEPRVIASHKGSAKLLIVDDEPINLQVLVNMLSLQNYTVIQAKNGLDALELLHKGFKPDLVLLDVMMPKMTGYEVTQKIRETWQASEMPVLLLTAKNQLSDLVAGFESGANDYLTKPVEKDELLARIKTHLNLLRLKNENLRLVAELEVTRQQQQMLLPSTEELELIEDLEIAAFMEPATEVGGDYYDVIQHQWGVKIGIGDVTGHGLESGVLMIMVQMAVRTLLESDIRNPVHFLTLLNLAVYGNLQRMKSEKNMSLMLLDYHQGKLVVSGQHEDIILVRAGGQVKLIDTVDLGFPVGLVEDIGEFVAEMVIELNPGDVAIVYTDGITEAENMEGVQYGLQRMMELAGQQQGRSATEIVDVILADVREFIGKQKVYDDITLLVLKQK
>NC_019693.1|WP_015146592.1|224501_224789_+|DUF2470-domain-containing-protein
MADLISAQVSDRICKHMNDDHADSVLLYAQIFGEVTDATSATLLAIDPLGMNLTAQVGEKSLPVRVTFDHALADSEDAHHTLIAMVKQARQLKTA
>NC_019693.1|WP_015146590.1|223014_224262_+|hypothetical-protein
MWSRKRFDIDYIDLIYGLGAALTVENSQRQGLQNDLEDWWGQDSTGETVACLSVRSGWDLLLQALQLPPGSEVAMSALTIPDMVTIVRAHGLVPVPIDLDPETMAPDPASLDRATGPRTRVIIIAHLFGGRVDLAPILAARDRVGAILVEDCAQAFTPGFRGHPEADVSCFSFGTIKFATALGGALLRVRDPQLADCLRQIQSTYPVQDSGNYTRRLLKYLGLKTLSSRPGFTALIWGCRRWGIDYDRLLNQSVKGFPKDELIWRLRHQPCAPLLALLRHRLQGYTEQRLAEQTHRGQRLIQLLQEYCPQIQVPGVATSPNMHWIVPILAEDPKLAIATLVNAGFDATQGHSMTVVDSPATHPEGEPRNTRELFQHLLYLPCYPAMDDQVLVSMAQALRPISFPLVSAFSRMGSA
>NC_019693.1|WP_015146589.1|221254_222658_+|hypothetical-protein
MKNLNLSLYAFHLCQSLDDAPDTHSKDAGLLWDSLRGLAAKIPFPELKKITEPTEANPETSLDFQAIEINHISLTGNLSTFKIHDTYSVDLTLSFQDKQAHFFPGNVVIFQPQALIDVTANLGKVLWLSGESEDVNELQLTRATQWAEQLCQQATYIEEDHLFNSPLFIFAADSVTILISLAEPNAIDLERAQENYYNLRNLFWTYQKIVVVEKLAKEGYQGARKLYSELEAQVQEFNQVFLQTPEERLKKLDELLQTIPQRLLDYNCKLRDLKANYTTIDVNWKNFKVSLSHILDESAGDKLSYWSDFATKTAPLYLTQIKTYIDYLEPGQVLFSDLINSIRATAEIEQVKSDRQRQQAEKDYYQQQQDDNQKLQNRIQAVGVGIAAGAIFASTAGSINEPWLFPNGQKMEVPFLPPHPFLLGLLGSIICSVGAWWLAETFINPGKNKSDKSSNQLAKNQQNPKSN
>NC_019693.1|WP_156823698.1|220881_221274_+|hypothetical-protein
MDRENKTMVSHAKKIAAFTALLQENLNNWIANHGESLLALQQQLDDDDEKNAQAIESWLKEREDLYKQYEAKLARPKRTLSLSGEKGFAGIKAPGKDKSLAEQIEQAVKNNTNLETSAPSPEQDREKPQS
>NC_019693.1|WP_015146587.1|216926_220910_+|CHAT-domain-containing-protein
MDEQRVQAYLALIQELLECPSGEEPQILSQSSELVDEGFVQVCELVAAQLQEEGQDNQAQFLRDVAQEVGQYLNSQTSAVATGEGPTQGTEQDYLNFLIEVLGAIEQSQGNPQVVYPLLQQNLDKLDLTLAETLQHLASQVFGQVESNQTYGIAGSIFLLSNLIQQFPLGNRADNLEIAIASYQSVLKVFTREVYPEDWAGVQNNLGITYYNRIREDRGQNIEKSILCYQAALDVFTRPAFPLKWAMAQNNLGEAYLFQVKGDRSENIEKAITYYEYALEVCTRHTFSKQWAMIQTNLGNAYFFRIRGKREENIEKSIRYCKAALEVCTQETLPYEWARSQNTLGNSYLFRIRGERANNIELAITALELALKVRKRESFPLDWAMSQNNLGNAYLFRINGNKADNIEQAIFSIEVALELCTNQTLPYEWARGHSSLGNAYLFRIRGERLDNIERSIRASEFALQVYTHESFPEEWATTQNNLGNAYLYRIQGERAENLERAITFMKASLEVYTHEGFPEQWATTQNNLGVAYLSRIRGERAENLERAITFMQTSLEVYTREGFPEQWARTQNNLGETYRNRIRGERAENLEISIAFLEASLQVYTRQAFPYEWARTQNNLGVVYQTRIQGERVENLDRAIAFLEASLQVYTREAFPEDWARTQNNLGSTYQARIRGERAENLERAISYLESSLQVYTREGFPYEWATTQVNLGGTYRNRIRGERAENLDRAIVCSEAALEIYTRTDFPQEHTKTLGILGLAYQAQSHYYSNDPIKKRTALQNAYIVLEQALDTVEYLRGEITSGDEAKRKLNEEWMGLYVLMVEVCLELGKYTAAIEYVDRSKARNLTELIATRDAYPRGDIPPEVRQRLQQLRQAISEEDRCLKQDPNPDYTHISQLREEFQANYPYKPLKFPDIQSLLDDETVILEWYILDEKFLTFTLTNQTLNLWASSEEDRQNLIDWTVAYIDDYDNNSQWRDSLPQRLETLAQILHLDEILQNLRQNFPNCQKLILIPHLFLHLFPLHALPIPVIATDGVRAQCLRPISGPNGHQEGLHIAPLQDIFPKGVTYAPNCQLLQQAQNRQRPHFNQLFAIQNPTEDLDWADVEIENIRTLFPEPETLAWEDATTANLLDEQRREILSQTHHLFFSCHAAFNPNSPLDSGLLLADGILTLENIIANLNLSNCSLVTLSACETGQVAIDTTDEYISLSSGFILAGSPSVLVSLWSVNQVSTALLLIRTYELLQQQPGQLAQSLQAAQKWLRETTVSGFEQWRQQCPLFSEEWREALQPVFAQMGQNKEEGINHRPYQSPYHWAAFCIVGQGEQNNG
>NC_019693.1|WP_015146586.1|216324_216573_-|hypothetical-protein
MTRKINLELSDDLSQRLESKAQIINLSLEAMILKSLEDLATQPDDPIAALIGTLSAENNDIASRHDDYIGEAIYSRELSSEK
>NC_019693.1|WP_015146585.1|215912_216335_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MKNSVFVDTSGWANLFIKTEPDHPYAVEWFTQARQQKYLMVTSNYIVLELVALLNSPLRVPRPQIFQYIDAIHSAPYLQLVRVNQQIENAAWELLKKRLDKTWSLVDATSFIIMQQLEITNALTSDHHFDQAGFVRLLKS
>NC_019693.1|WP_015146584.1|215472_215685_-|hypothetical-protein
MTGQPTENQPQAIEARVTSLEIELTQIKEVLATVTSPQQPWWERIAGSHANDPTFESVIQLGQEWRKTAE
>NC_019693.1|WP_015146594.1|230446_231829_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MDRVTQRETIAAIATAIVPQQGSIGIVRLSGSQALAIAQTLFHAPGSQPWETHRILYGTIRHPKTQQIVDEALLLLMKSPRSFTREDVVEFHCHGGIIPVQQVLQLCLELGARLAQPGEFTLRAFLNGRLDLTQAESVADLVGAQSPAASQAALAGLQGKLAHPIRQLRTQCLDILAEIEARIDFEEDLPPLNEPEIIQSIQSIIQEVEKILGTANQGELLRMGLKVAIVGRPNVGKSSLLNAWSRSDRAIVTNLPGTTRDVVESQLVVQGIPVQVLDTAGIRATEDTVEKIGVERSRLAAQSADLVLLTLDAQAGWTADDYEIYQQVNHKPIVVIFNKIDLVEQIPLLPNLDNIRETVNTSAAHQQGIEALETAILNTVHAGNLQAENLDFAINQRQAAALTRAQTALEQVQTTIDQQLPLDFWTIDLRGAIQALGEITGEEVTESVLDRIFSRFCIGK
>NC_019693.1|WP_015146595.1|232002_232572_+|DUF2062-domain-containing-protein
MLHKHPLPINSRRTQIKRVRSASLFSKRQRSRSRWQRFWRYYYWRLVRQKGSPEFLARGLAAGVFAGLFPLFGLQTILGVALAILFRGNKWMAVAGTWVSNPLTYGPIFWLNFEVGQWLLKSHEVFELERIQSTKALLEVGADFLIILFVGCLVMASFSAFLSYFLGLKLIRRWRTLNRGWRRRHHAGR
>NC_019693.1|WP_015146596.1|232583_233120_-|Uma2-family-endonuclease
MTPEDYFAGEEISPIRREYIRGEVYAMSASTPVHNMITLNLATLIRKQVRGTECYAFVQDIKIRIETADVFYYPDLTVTCDPRDQQFTDSFIRYPCLIVEVLSESTEAFDRGDKFADYRQIETLKEYLVISQTRPSVECFRRNHSGRWELYSYQGQEQIRLTSLNLVIDMATLYEDVW
>NC_019693.1|WP_083896723.1|233186_234851_-|hypothetical-protein
MVKRWWVGVGILKFGGCLEGRMNHRLHRFSPMAGMIAAMAIVAGGLGPVSFSGRFEGWELQALASESPLFNPPLAIGEVTATAKDITVFISGPISGSGAIVHRQGNVYTVLTTKTVVSGRGVYEVVTGDGRRYSVSPEGVILLPLVDLAVLQFTSSETYPVAQLAEPSDSQIYLTVANQPQTTLFAAGNLVSTAGTNLSDGYDLLYNSALQSAGSGGPVVDRWGRLIGIQGRFNTQSPTVNSAIAVSNFLRLAPTVGLNLGWRGWILSNIIQPGSKPRAIALSSDGTLLATDGGYNRIQLWDWQSSQLNATLTGHNSEVNSLAISPNKQILVSGDQQGQAIIWNLRTGQIANTITRSRPNLSNPITSVAITANGQTLITGSNQGIELWEINTGRLVLTLPESGEANAIAISPDSRTLVSGHLDNTVKVWNLLNGNLVQTLPAGERGFIVESVAISPDGNTIAAGTYREIRLWNLERGIRQRTIVAHCDLCYVYDLAFTRDGTGIISTSEDGTKIWNIADGTLLRTLDGSAKTFALSGDRTLILGGDTLRIWQVP
>NC_019693.1|WP_015146598.1|234795_236685_-|WD40-repeat-containing-protein
MKGWQKFQGPRLFRALGVALGETPVTPRLRPRDPIRVLTVVFGLMLPVGMMESAEAQSTYTDITNHWARTCIETLAERDILAVFSSETFRPEDPIQRVEFASVVRKAFPNVEPVRDPIEFIDLPTDYWGREIVQDAYRSGFISPYSGRAFNPTQVIPRWQAIALLTTGLRYKSPENGLEMVEASLADWEGIPDYARGAIAAGIQNRLVVNYPDPRTLNPTEPLSRGELASMICQVQEDIGAIALVPQQYVASPDAIATAETPTAETPTAETPTAETPTVETPTAETPTAETPTPPTPIAAGNQRWQTAVLTNVLNFQPTGITPDSQVEQCVTDTSGTPRCESISASMDATAIAIDGQGFVMASGHRGADLAPINLWDLRTGDRIRTLEGHRGRVGALAIAPNGQWALSGGGDGEIKIWDIRTGTLTQTLTGHTNEVTGLEIASNGNTAISSSRDRTVKLWDLNTGEVLRTLEDRQTAMLDVAVSSDGRMAASSSEDGLVRLWNLQSGELIRTISADINAVRTLAFSPNGQTLATGGEGTIRLWNIANGDLVRTIARNPEATFFEVAFSNDGETLVGTVQEGDISAIRIWDVRTGALLHFFPTAAAAIALTPDGQTLVGGGWDIKIWRMP
>NC_019693.1|WP_015146599.1|236934_237705_-|class-I-SAM-dependent-methyltransferase
MLNSQSSVPKIIIPDELLPPKELRLSVGGSFKAIGTEFFRYFIEIAGLQPDEAVLDVGCGVGRMAVPLTQYLSDRGRYEGFDIVESAITWCQSVISPRYPNFQFQRADLYNQYYNPTGQAQANTYRFPYSDNHFDFVFLTSVFTHILPDGIENYLREISRVLKPGGRALITAFLLNKDSLYCLESGLSALEFTEIFENYRLADKIFPESAVAYEEQFFITLAEQVGLRVNSPIYYGCWCGREDFLSFQDILLMGKS
>NC_019693.1|WP_015146600.1|238088_239405_-|homoserine-dehydrogenase
MTFKIGLLGLGTVGAGTAQILLDSVGRHPLLQELEIARVGVRSPDKPRDIDLPAGILTTDLESIVTDPEIDIVVELIGGLEPARSLMLQAIASGKHVVTANKAAIALHGAEIFTAANEKGVYVMLEAAVGGGIPVIQPLKQSLGSNRIQGVMGIINGTTNYILTRMQLEGADFEAVLADAQKLGYAEADPTADVDGLDAADKIAILASLAFGGRIKREQVYAEGIRQVSAEDIAYAEKLGFVIKLLAIAKREEGPTPQIQTDVEDRLQLRVHPTLVPKQHPLANVNGVYNAIFVEGDPIGQVMFYGRGAGAGPTASAVVADILNVAAVLKTETEPIPHPLLSCSHQHYCAIAPMEDVVTRFYARFLTQDSPGVIGELGTIFGKNGVSLESVVQIGMRENQAEIVVVTHDVKEGNFNHALAEIRNLEAIVSIPSLLRVL
>NC_019693.1|WP_015146601.1|239674_240052_-|PIN-domain-containing-protein
MIYLDTHVVVWLYAGLTDKFSDLAKSLINAQTPYISPMVRLELKYLYEIGRIGELPDLIIADLSHVLGLKICQEDFNQVIGYSLGLDWTRDPFDRLIVAQAALNGNILLTKDTKILANYAQAKWE
>NC_019693.1|WP_015146602.1|240038_240275_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MKSITPKELSGNLENLLDEVLRTGIPLEIERGGKRLRIIPVEPLDKLEKLVHRPHVILGDPDTLVESNWEQEVNLDLP
>NC_019693.1|WP_044196223.1|240340_241105_-|Uma2-family-endonuclease
MTQLTTDISTQTLTFEEYLFYQGKPDVMYELYRGQLIAMPIPPGLHTRICSFLTALFQRYIVTHDLPLVATGLTGVRTEDNTSRIPDVVICYAELWDRVCRRKGAGVLDFEEKPVMVIEVTSDNWQEDYIRKRAEYAMANIPEYWIIDPNQSKIQVCFNPNNEKGYEELEFLPGQDLHLVQFPDFILPVNRIFSPPLVTDLIRQEQAERKQLEERVQEQRQRVQEQPQGVQEERQRADRLAQRLRDMGIDPDAV

Crispr_ID: NC_019693_6

• CRISPR_ID: NC_019693_6
• CRISPR_location: 237979-238085
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_6

Consensus_repeat	Method
TGTAGCCCCAGGCTTGAGCCTGCGGGTTTC	CRISPRCasFinder

spacers of NC_019693_6

>6.1|238009|47|NC_019693|CRISPRCasFinder
CATTGCGAGGTTGTTATAAACCAGCCCGCGCAGGCGGGCTTCGTCCG

CRISPR arrays and Neighbor proteins around NC_019693_6

CRISPR arrays

The CRISPR arrays of NC_019693_6

>merge|NC_019693|6|237979-238085|CRISPRCasFinder
TGTAGCCCCAGGCTTGAGCCTGCGGGTTTCCATTGCGAGGTTGTTATAAACCAGCCCGCGCAGGCGGGCTTCGTCCGTGTAGCCCCAGGCTTGAGCCTGCGGGTTTC

>NC_019693|6|6|237979-238085|CRISPRCasFinder
TGTAGCCCCAGGCTTGAGCCTGCGGGTTTC	CATTGCGAGGTTGTTATAAACCAGCCCGCGCAGGCGGGCTTCGTCCG
TGTAGCCCCAGGCTTGAGCCTGCGGGTTTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015146599.1|236934_237705_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_019693.1|WP_015146609.1|247676_248900_-|coproporphyrinogen-III-oxidase	unknown	unknown	gnl|CDD|236007
NC_019693.1|WP_156823699.1|230160_230298_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146596.1|232583_233120_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_019693.1|WP_015146607.1|244133_245138_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|132997
NC_019693.1|WP_015146600.1|238088_239405_-|homoserine-dehydrogenase	unknown	unknown	gnl|CDD|235783
NC_019693.1|WP_015146608.1|245165_247052_-|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|376350
NC_019693.1|WP_044196225.1|241508_242132_-|transferase	unknown	unknown	gnl|CDD|100053
NC_019693.1|WP_015146595.1|232002_232572_+|DUF2062-domain-containing-protein	unknown	unknown	gnl|CDD|378263
NC_019693.1|WP_044196227.1|242462_244106_-|nucleotide-pyrophosphatase	unknown	unknown	gnl|CDD|225914
NC_019693.1|WP_015146592.1|224501_224789_+|DUF2470-domain-containing-protein	unknown	unknown	gnl|CDD|378456
NC_019693.1|WP_015146593.1|225259_228172_+|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|274362
NC_019693.1|WP_015146598.1|234795_236685_-|WD40-repeat-containing-protein	unknown	unknown	gnl|CDD|238121
NC_019693.1|WP_015146594.1|230446_231829_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl|CDD|235392
NC_019693.1|WP_044196223.1|240340_241105_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NC_019693.1|WP_015146610.1|249154_250234_+|PIN/TRAM-domain-containing-protein	unknown	unknown	gnl|CDD|227292
NC_019693.1|WP_015146602.1|240038_240275_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl|CDD|376852
NC_019693.1|WP_015146590.1|223014_224262_+|hypothetical-protein	unknown	unknown	gnl|CDD|99740
NC_019693.1|WP_015146601.1|239674_240052_-|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350220
NC_019693.1|WP_083896723.1|233186_234851_-|hypothetical-protein	unknown	unknown	gnl|CDD|238121

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015146599.1|236934_237705_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.34759e-22
NC_019693.1|WP_015146609.1|247676_248900_-|coproporphyrinogen-III-oxidase	gnl|CDD|236007	PRK07379, PRK07379, coproporphyrinogen III oxidase; Provisional.	0
NC_019693.1|WP_015146596.1|232583_233120_-|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	2.54996e-42
NC_019693.1|WP_015146607.1|244133_245138_-|glycosyltransferase-family-2-protein	gnl|CDD|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	8.06955e-27
NC_019693.1|WP_015146600.1|238088_239405_-|homoserine-dehydrogenase	gnl|CDD|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	0
NC_019693.1|WP_015146608.1|245165_247052_-|EAL-domain-containing-protein	gnl|CDD|376350	pfam00563, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.	4.2251e-55
NC_019693.1|WP_044196225.1|241508_242132_-|transferase	gnl|CDD|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	1.26574e-40
NC_019693.1|WP_015146595.1|232002_232572_+|DUF2062-domain-containing-protein	gnl|CDD|378263	pfam09835, DUF2062, Uncharacterized protein conserved in bacteria (DUF2062). This domain, found in various prokaryotic proteins, has no known function.	9.5281e-43
NC_019693.1|WP_044196227.1|242462_244106_-|nucleotide-pyrophosphatase	gnl|CDD|225914	COG3379, COG3379, Uncharacterized conserved protein [Function unknown].	1.86938e-16
NC_019693.1|WP_015146601.1|239674_240052_-|PIN-domain-containing-protein	gnl|CDD|350220	cd09872, PIN_Sll0205-like, VapC-like PIN domain of Sll0205 protein and homologs. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of the Synechocystis sp. (strain PCC 6803) Sll0205 protein and other uncharacterized homologs are included in this subfamily. They are similar to the PIN domains of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.06465e-14
NC_019693.1|WP_015146593.1|225259_228172_+|SpoIIE-family-protein-phosphatase	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	4.10239e-69
NC_019693.1|WP_015146598.1|234795_236685_-|WD40-repeat-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	8.18024e-69
NC_019693.1|WP_015146594.1|230446_231829_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl|CDD|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NC_019693.1|WP_044196223.1|240340_241105_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	3.12364e-33
NC_019693.1|WP_015146610.1|249154_250234_+|PIN/TRAM-domain-containing-protein	gnl|CDD|227292	COG4956, COG4956, Integral membrane protein (PIN domain superfamily) [General function prediction only].	2.41175e-157
NC_019693.1|WP_015146602.1|240038_240275_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl|CDD|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	0.000314582
NC_019693.1|WP_015146590.1|223014_224262_+|hypothetical-protein	gnl|CDD|99740	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.	5.11312e-33
NC_019693.1|WP_015146592.1|224501_224789_+|DUF2470-domain-containing-protein	gnl|CDD|378456	pfam10615, DUF2470, Protein of unknown function (DUF2470). This family is a putative haem-iron utilisation family, as many members are annotated as being pyridoxamine 5'-phosphate oxidase-related, FMN-binding; however this could not be confirmed.	2.43177e-27
NC_019693.1|WP_083896723.1|233186_234851_-|hypothetical-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	1.1966e-47

Protein sequences

>NC_019693.1|WP_015146599.1|236934_237705_-|class-I-SAM-dependent-methyltransferase
MLNSQSSVPKIIIPDELLPPKELRLSVGGSFKAIGTEFFRYFIEIAGLQPDEAVLDVGCGVGRMAVPLTQYLSDRGRYEGFDIVESAITWCQSVISPRYPNFQFQRADLYNQYYNPTGQAQANTYRFPYSDNHFDFVFLTSVFTHILPDGIENYLREISRVLKPGGRALITAFLLNKDSLYCLESGLSALEFTEIFENYRLADKIFPESAVAYEEQFFITLAEQVGLRVNSPIYYGCWCGREDFLSFQDILLMGKS
>NC_019693.1|WP_015146598.1|234795_236685_-|WD40-repeat-containing-protein
MKGWQKFQGPRLFRALGVALGETPVTPRLRPRDPIRVLTVVFGLMLPVGMMESAEAQSTYTDITNHWARTCIETLAERDILAVFSSETFRPEDPIQRVEFASVVRKAFPNVEPVRDPIEFIDLPTDYWGREIVQDAYRSGFISPYSGRAFNPTQVIPRWQAIALLTTGLRYKSPENGLEMVEASLADWEGIPDYARGAIAAGIQNRLVVNYPDPRTLNPTEPLSRGELASMICQVQEDIGAIALVPQQYVASPDAIATAETPTAETPTAETPTAETPTVETPTAETPTAETPTPPTPIAAGNQRWQTAVLTNVLNFQPTGITPDSQVEQCVTDTSGTPRCESISASMDATAIAIDGQGFVMASGHRGADLAPINLWDLRTGDRIRTLEGHRGRVGALAIAPNGQWALSGGGDGEIKIWDIRTGTLTQTLTGHTNEVTGLEIASNGNTAISSSRDRTVKLWDLNTGEVLRTLEDRQTAMLDVAVSSDGRMAASSSEDGLVRLWNLQSGELIRTISADINAVRTLAFSPNGQTLATGGEGTIRLWNIANGDLVRTIARNPEATFFEVAFSNDGETLVGTVQEGDISAIRIWDVRTGALLHFFPTAAAAIALTPDGQTLVGGGWDIKIWRMP
>NC_019693.1|WP_083896723.1|233186_234851_-|hypothetical-protein
MVKRWWVGVGILKFGGCLEGRMNHRLHRFSPMAGMIAAMAIVAGGLGPVSFSGRFEGWELQALASESPLFNPPLAIGEVTATAKDITVFISGPISGSGAIVHRQGNVYTVLTTKTVVSGRGVYEVVTGDGRRYSVSPEGVILLPLVDLAVLQFTSSETYPVAQLAEPSDSQIYLTVANQPQTTLFAAGNLVSTAGTNLSDGYDLLYNSALQSAGSGGPVVDRWGRLIGIQGRFNTQSPTVNSAIAVSNFLRLAPTVGLNLGWRGWILSNIIQPGSKPRAIALSSDGTLLATDGGYNRIQLWDWQSSQLNATLTGHNSEVNSLAISPNKQILVSGDQQGQAIIWNLRTGQIANTITRSRPNLSNPITSVAITANGQTLITGSNQGIELWEINTGRLVLTLPESGEANAIAISPDSRTLVSGHLDNTVKVWNLLNGNLVQTLPAGERGFIVESVAISPDGNTIAAGTYREIRLWNLERGIRQRTIVAHCDLCYVYDLAFTRDGTGIISTSEDGTKIWNIADGTLLRTLDGSAKTFALSGDRTLILGGDTLRIWQVP
>NC_019693.1|WP_015146596.1|232583_233120_-|Uma2-family-endonuclease
MTPEDYFAGEEISPIRREYIRGEVYAMSASTPVHNMITLNLATLIRKQVRGTECYAFVQDIKIRIETADVFYYPDLTVTCDPRDQQFTDSFIRYPCLIVEVLSESTEAFDRGDKFADYRQIETLKEYLVISQTRPSVECFRRNHSGRWELYSYQGQEQIRLTSLNLVIDMATLYEDVW
>NC_019693.1|WP_015146595.1|232002_232572_+|DUF2062-domain-containing-protein
MLHKHPLPINSRRTQIKRVRSASLFSKRQRSRSRWQRFWRYYYWRLVRQKGSPEFLARGLAAGVFAGLFPLFGLQTILGVALAILFRGNKWMAVAGTWVSNPLTYGPIFWLNFEVGQWLLKSHEVFELERIQSTKALLEVGADFLIILFVGCLVMASFSAFLSYFLGLKLIRRWRTLNRGWRRRHHAGR
>NC_019693.1|WP_015146594.1|230446_231829_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MDRVTQRETIAAIATAIVPQQGSIGIVRLSGSQALAIAQTLFHAPGSQPWETHRILYGTIRHPKTQQIVDEALLLLMKSPRSFTREDVVEFHCHGGIIPVQQVLQLCLELGARLAQPGEFTLRAFLNGRLDLTQAESVADLVGAQSPAASQAALAGLQGKLAHPIRQLRTQCLDILAEIEARIDFEEDLPPLNEPEIIQSIQSIIQEVEKILGTANQGELLRMGLKVAIVGRPNVGKSSLLNAWSRSDRAIVTNLPGTTRDVVESQLVVQGIPVQVLDTAGIRATEDTVEKIGVERSRLAAQSADLVLLTLDAQAGWTADDYEIYQQVNHKPIVVIFNKIDLVEQIPLLPNLDNIRETVNTSAAHQQGIEALETAILNTVHAGNLQAENLDFAINQRQAAALTRAQTALEQVQTTIDQQLPLDFWTIDLRGAIQALGEITGEEVTESVLDRIFSRFCIGK
>NC_019693.1|WP_156823699.1|230160_230298_+|hypothetical-protein
MGSSGWRSHLTMNGWVEGSPDVAIARYEERVFSSLHTGAIVSTSA
>NC_019693.1|WP_015146593.1|225259_228172_+|SpoIIE-family-protein-phosphatase
MTSNSGIKVSWSLTKSETTLIQILFVAVSYFLISEFGAVFLALKEGGSPVWPGSGVALAGVLLLGYPMGIAVVLGNVLVNFFLTEWSIADMVMNFNFTLGNTLETLSAAYFIHKFSVNFKWFSRVKDVIYFVIFAGLISPMFSATFGAGTIWLLGRIPWDVVPGLWVTWWIGDVVGILVFAPVLLVFGQGINEFFQKSQQRWMEGLVFVFITLVTCQMAFLKGYPVEYMLLPLLVWTVFRFGQWSATLLLLIGSVLAILATANDLGPFIRSNLNESLILLQSFVGVFSLTTLTLSAVICENEQAQQRLETANIQLQHLDRLKDEFLANTSHELRTPLNGIIGIAESLIDGATGELPVPTRANLAMISSSGRRLSNLVNDLLDFSKLKHKTLELQLKPIDLRSLAEIVFTLSLPLVGDKNLNLVNNISLDLPAVTADENRLQQILHNLIGNAIKFTETGTIEISAQRIFGDESLEPLSSVSQVEITIADTGIGIAEDKLERIFESFEQAEGSTGRMYGGTGVGLAIAKQLVELHGGQIWVNSRLGEGSKFSFTLPLSGEKIENSSETLPLLKQFATADLNPEPLEPRVIASHKGSAKLLIVDDEPINLQVLVNMLSLQNYTVIQAKNGLDALELLHKGFKPDLVLLDVMMPKMTGYEVTQKIRETWQASEMPVLLLTAKNQLSDLVAGFESGANDYLTKPVEKDELLARIKTHLNLLRLKNENLRLVAELEVTRQQQQMLLPSTEELELIEDLEIAAFMEPATEVGGDYYDVIQHQWGVKIGIGDVTGHGLESGVLMIMVQMAVRTLLESDIRNPVHFLTLLNLAVYGNLQRMKSEKNMSLMLLDYHQGKLVVSGQHEDIILVRAGGQVKLIDTVDLGFPVGLVEDIGEFVAEMVIELNPGDVAIVYTDGITEAENMEGVQYGLQRMMELAGQQQGRSATEIVDVILADVREFIGKQKVYDDITLLVLKQK
>NC_019693.1|WP_015146592.1|224501_224789_+|DUF2470-domain-containing-protein
MADLISAQVSDRICKHMNDDHADSVLLYAQIFGEVTDATSATLLAIDPLGMNLTAQVGEKSLPVRVTFDHALADSEDAHHTLIAMVKQARQLKTA
>NC_019693.1|WP_015146590.1|223014_224262_+|hypothetical-protein
MWSRKRFDIDYIDLIYGLGAALTVENSQRQGLQNDLEDWWGQDSTGETVACLSVRSGWDLLLQALQLPPGSEVAMSALTIPDMVTIVRAHGLVPVPIDLDPETMAPDPASLDRATGPRTRVIIIAHLFGGRVDLAPILAARDRVGAILVEDCAQAFTPGFRGHPEADVSCFSFGTIKFATALGGALLRVRDPQLADCLRQIQSTYPVQDSGNYTRRLLKYLGLKTLSSRPGFTALIWGCRRWGIDYDRLLNQSVKGFPKDELIWRLRHQPCAPLLALLRHRLQGYTEQRLAEQTHRGQRLIQLLQEYCPQIQVPGVATSPNMHWIVPILAEDPKLAIATLVNAGFDATQGHSMTVVDSPATHPEGEPRNTRELFQHLLYLPCYPAMDDQVLVSMAQALRPISFPLVSAFSRMGSA
>NC_019693.1|WP_015146600.1|238088_239405_-|homoserine-dehydrogenase
MTFKIGLLGLGTVGAGTAQILLDSVGRHPLLQELEIARVGVRSPDKPRDIDLPAGILTTDLESIVTDPEIDIVVELIGGLEPARSLMLQAIASGKHVVTANKAAIALHGAEIFTAANEKGVYVMLEAAVGGGIPVIQPLKQSLGSNRIQGVMGIINGTTNYILTRMQLEGADFEAVLADAQKLGYAEADPTADVDGLDAADKIAILASLAFGGRIKREQVYAEGIRQVSAEDIAYAEKLGFVIKLLAIAKREEGPTPQIQTDVEDRLQLRVHPTLVPKQHPLANVNGVYNAIFVEGDPIGQVMFYGRGAGAGPTASAVVADILNVAAVLKTETEPIPHPLLSCSHQHYCAIAPMEDVVTRFYARFLTQDSPGVIGELGTIFGKNGVSLESVVQIGMRENQAEIVVVTHDVKEGNFNHALAEIRNLEAIVSIPSLLRVL
>NC_019693.1|WP_015146601.1|239674_240052_-|PIN-domain-containing-protein
MIYLDTHVVVWLYAGLTDKFSDLAKSLINAQTPYISPMVRLELKYLYEIGRIGELPDLIIADLSHVLGLKICQEDFNQVIGYSLGLDWTRDPFDRLIVAQAALNGNILLTKDTKILANYAQAKWE
>NC_019693.1|WP_015146602.1|240038_240275_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MKSITPKELSGNLENLLDEVLRTGIPLEIERGGKRLRIIPVEPLDKLEKLVHRPHVILGDPDTLVESNWEQEVNLDLP
>NC_019693.1|WP_044196223.1|240340_241105_-|Uma2-family-endonuclease
MTQLTTDISTQTLTFEEYLFYQGKPDVMYELYRGQLIAMPIPPGLHTRICSFLTALFQRYIVTHDLPLVATGLTGVRTEDNTSRIPDVVICYAELWDRVCRRKGAGVLDFEEKPVMVIEVTSDNWQEDYIRKRAEYAMANIPEYWIIDPNQSKIQVCFNPNNEKGYEELEFLPGQDLHLVQFPDFILPVNRIFSPPLVTDLIRQEQAERKQLEERVQEQRQRVQEQPQGVQEERQRADRLAQRLRDMGIDPDAV
>NC_019693.1|WP_044196225.1|241508_242132_-|transferase
MALVQWVPSSIGAGLRGLVYKTIFGKLGKGVCIKTGVEFFCAYRMQIGHKVSIGRDVRIRSVGPKDKIQIGDGVSFDRGVDIKAHGNQKGIEIGDRTYIGPYTCLSGGKLKIGKDCLIASHSSIYSNNHIFANVGQNINQQGNSYEGITIEDNCWLGTGVKVMDGVTIGEGSIIGAGAIVTKNIPPYSIAVGVPAKVISSRRESVGV
>NC_019693.1|WP_044196227.1|242462_244106_-|nucleotide-pyrophosphatase
MKNSVIAIGLDAAEPDLLETWMDQGYLSHLKQLKDRGAYGRLTNLEHYKAETPWTTFLTGCLPEKTGYWSPIKFHEGSYNVSDIGAYDFQEYPPFYALGDEYRVAVFDVPQSRLCDRVNGEQVLAWGAHSPQTPSLSHPPELLNQLNRDYGKHPALHRDHGDWWDKAYLSRLQKNLHQGITRRGAIVRNLLKQERWDLLLTVFGETHSAGHDLWYLSQPDHPLYEHKLESAADDPMLAVFESVDRTLGNLLAEVPEDSYLVIFSAHGSGNNTTDVPSMLFLPEFLYRFSFPGKVAIASGTAGTIPEAIVSAPRRKTWTGEIWERKYSPNPLKQLLRQQLPSQVHPLLDRLLGTFGEAPLGSPEQLRQQGNPLFWQPSTWYSPLWPQMKAFAIPSYSEGYIRINLAGREPNGIVSPEEYDGLCQELTAQLYAWTNARTGGPVVKKVIYTPPNSGTRPDADLVVVWHDTPADVIDCGQYGRIGPVPYRRTGSHRNRGFLNITGPGIRPGTQLREGHGVDLAPTLLHLMNAPIPDYYEGISLVENSVVVA
>NC_019693.1|WP_015146607.1|244133_245138_-|glycosyltransferase-family-2-protein
MNAIAFTIAIPTYNGAARLPQLLDCLRSQIRTEDFTWEIVVIDNNSQDNTAEVIRQYQIDWPSASPLHYYFEPQQGLAFARQRAIDEAQGTWVGFLDDDNLPAPDWVAEAYNFAHSYPQAGAFGGQIHGQFETPPPENFHRIASFLAIRERGSKPHLYQPNQLSLPPGAGLVVRKQAWCETVPRRLQLIGRVKGSSLAGEDFETLLYLHQGGWEIWYCPTLHSYHQIPQERLEQASLLSLIRGCGLCICHLRLLNASPREKPLVIARIFLGNLRRILRHLIQYRGLVKTDPVAACELEFFISSFLSPVYYLQSQLAQKQVNSNEPSPRLNCPAN
>NC_019693.1|WP_015146608.1|245165_247052_-|EAL-domain-containing-protein
MKPVDLTIAIPTYNGETRLTDVLDRLRSQVGTEKFSWEIIVVDNNSSDRTAAVVRDYQKTWPSAYPLRYCFAPEQGAAFARQRAVEKAQGELIGFLDDDNLPEPDWVAAAYQFGKTHPEVGAFGSQIHGLFYEKTPEEKLPENFKKIACFLAIVERGNTPRQYDPQHKILPPGAGLVVRKAVWLKSVPKRLVLNHTGKDAGLASEDLEVLLHIQKAGWEIWYNPAMVVYHKIPNQRLEPEYLKRLVRCVGLSRHRLRMMTLNSWQRPLAFPAYLANDLRRLVLHGIRHGIGIKNDTAATCEREFLTSTLMSPLFLLKQQGFKSLGRSGDRPGQKQDETALEQLAEAFEEQRFRLHSQGVYPLNGTTGDRPHTEILLRLEDRGGQLLMPNQFMPVAKRYNLMRTIDRWTIRKLCVQIAEVGDKCSGEIYEINLSESSLCDRYLIDFIVQELAFYQISPALLCFCLPEAVAVGHLPRIKELIARLKSIGCQFSLDGVGAAQSSGEYLQELPINYLKLEGDLIHFLPHDSRSLNTVKTIQKKGISLGIKTIATHVENPELLEQAQRMGFNYVQGYGIERPHPFCVESPVSRHWVSNFLKPELSIEPAPSESLVSSVSELLSESSLESSLIV
>NC_019693.1|WP_015146609.1|247676_248900_-|coproporphyrinogen-III-oxidase
MIPEIPRSAYLHIPFCRRRCFYCDFPVSVVGDRKQGEDSGTIVEYVDWLIREIENSPVWGQPLSTVFFGGGTPSLLSVSQLSQLLDSLDRRLGIAADAEISMEMDPGTFDREHLRGYCLGGINRVSLGVQAFQDDLLADCGRSHRTRDILNAVELMGEVGIENFSLDLISGLPHQTLEQWQDSLNQAVALNPAHISSYDLIVEAGTAFSRTYQPGVSPLPTDEISAQMYRVAVETLTAAGYEHYEVSNYAQSGYQCRHNRVYWENRPCYGFGMGAASYLGGQRFTRPRTRREYYAWVQEWQSSGGVLSIPETPTEEVLLETLMLGLRLADGIDIARFTQQFGGDRLRQLWHCLLPYYRQGWVEVHSRSEPLDFGPTLPPSGAIRLSDPEGFLFSNTILATIFEALEK
>NC_019693.1|WP_015146610.1|249154_250234_+|PIN/TRAM-domain-containing-protein
MLNAIIILSFILAAAGIGFYSTELLPASAMAQVSNLDGLRSVTTGFAALVGGAVGLAVQTTYRRMEKQVRQMPIDMLITRAIGLVMGLLVANLMLAPVFLLPIPHEFGFIKPLAAILGSVMFAFLGVTLADTHGRAFLRLINPSSLESMLVAEGTLKPAATKVLDTSCIIDGRVETLLGTGFLEGQILVPQFVLQELQMVADASNDQKRVRGRRGLDVLNRIKETYAERIVIHPADYEDLQTVDAKLVRLAQEINATLLTNDYNLSKVATVQKVLVLNINDLTQAVRPVYLPGDSLDLKILKEGKEEAQGVGYLDDGTMVVVEEGSKYIGDQLRVVVTSSLQTAAGRMIFARPHASMVA

Crispr_ID: NC_019693_7

• CRISPR_ID: NC_019693_7
• CRISPR_location: 272915-273023
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_7

Consensus_repeat	Method
AAAACTCGTTCCTAGGCAGAGCCTAGGAAT	CRISPRCasFinder

spacers of NC_019693_7

>7.1|272945|49|NC_019693|CRISPRCasFinder
TCTCCACTGGAGGCCACACCTCCTTTTCAAACCGCGTTAAACCTCATTA

CRISPR arrays and Neighbor proteins around NC_019693_7

CRISPR arrays

The CRISPR arrays of NC_019693_7

>merge|NC_019693|7|272915-273023|CRISPRCasFinder
AAAACTCGTTCCTAGGCAGAGCCTAGGAATTCTCCACTGGAGGCCACACCTCCTTTTCAAACCGCGTTAAACCTCATTAAAAACTCGTTCCTAGGCAGAGCCTAGGAAT

>NC_019693|7|7|272915-273023|CRISPRCasFinder
AAAACTCGTTCCTAGGCAGAGCCTAGGAAT	TCTCCACTGGAGGCCACACCTCCTTTTCAAACCGCGTTAAACCTCATTA
AAAACTCGTTCCTAGGCAGAGCCTAGGAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_044194246.1|268782_269325_-|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl|CDD|198397
NC_019693.1|WP_044194243.1|265290_266904_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146616.1|257411_258902_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_019693.1|WP_015146630.1|274896_275538_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146638.1|281816_282203_+|BON-domain-containing-protein	unknown	unknown	gnl|CDD|335963
NC_019693.1|WP_015146631.1|275567_276395_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146625.1|271669_272542_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238119
NC_019693.1|WP_015146633.1|276984_277275_+|plasmid-stabilization-system-protein	unknown	unknown	unknown
NC_019693.1|WP_015146624.1|269980_271609_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380492
NC_019693.1|WP_083896724.1|260483_262067_-|DUF4101-domain-containing-protein	unknown	unknown	gnl|CDD|270916
NC_019693.1|WP_015146623.1|269421_269745_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146619.1|262627_264988_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224054
NC_019693.1|WP_015146628.1|273511_274429_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146617.1|258993_260427_-|hypothetical-protein	unknown	unknown	gnl|CDD|379138
NC_019693.1|WP_015146639.1|282498_283938_-|cation:proton-antiporter	unknown	unknown	gnl|CDD|223551
NC_019693.1|WP_015146621.1|266966_268712_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_019693.1|WP_015146637.1|280756_281287_-|acetolactate-synthase-small-subunit	unknown	unknown	gnl|CDD|214364
NC_019693.1|WP_015146635.1|278694_280122_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146634.1|277412_278597_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146632.1|276757_276988_+|addiction-module-protein	unknown	unknown	gnl|CDD|378247

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_044194246.1|268782_269325_-|GIY-YIG-nuclease-family-protein	gnl|CDD|198397	cd10450, GIY-YIG_AtGrxS16_like, GIY-YIG domain found in CAXIP1-like proteins, iron-sulfur cluster assembly proteins, and similar proteins. The family includes CAX-interacting protein-1 (CXIP1)-like proteins and iron-sulfur cluster assembly proteins, both of which contain a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC. CAXIP1 is a novel PICOT (protein kinase C-interacting cousin of thioredoxin) domain-containing Arabidopsis protein that activates H+/Ca2+ exchanger CAX1, and its homolog CAX4, but not CAX2 or CAX3. Iron-sulfur cluster assembly proteins in this family also contain a C-terminal NifU-like domain that corresponds to a common region between the NifU protein from nitrogen-fixing bacteria and rhodobacterial species. The biochemical function of NifU is unknown.	5.24404e-36
NC_019693.1|WP_015146616.1|257411_258902_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.63691e-73
NC_019693.1|WP_015146625.1|271669_272542_+|VWA-domain-containing-protein	gnl|CDD|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	4.52412e-09
NC_019693.1|WP_015146624.1|269980_271609_+|ABC-transporter-substrate-binding-protein	gnl|CDD|380492	cd06268, PBP1_ABC_transporter_LIVBP-like, periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.	1.50157e-53
NC_019693.1|WP_083896724.1|260483_262067_-|DUF4101-domain-containing-protein	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.08333e-72
NC_019693.1|WP_015146619.1|262627_264988_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.9863e-64
NC_019693.1|WP_015146617.1|258993_260427_-|hypothetical-protein	gnl|CDD|379138	pfam13354, Beta-lactamase2, Beta-lactamase enzyme family. This family is closely related to Beta-lactamase, pfam00144, the serine beta-lactamase-like superfamily, which contains the distantly related pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	1.55022e-14
NC_019693.1|WP_015146639.1|282498_283938_-|cation:proton-antiporter	gnl|CDD|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	1.54853e-60
NC_019693.1|WP_015146621.1|266966_268712_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.04762e-72
NC_019693.1|WP_015146632.1|276757_276988_+|addiction-module-protein	gnl|CDD|378247	pfam09720, Unstab_antitox, Putative addiction module component. This entry defines several short bacterial proteins, typically about 75 amino acids long, which are always found as part of a pair (at least) of small genes. The other protein in the pair always belongs to a family of plasmid stabilisation proteins (IPR007712). It is likely that this protein and its partner comprise some form of addiction module - a pair of genes consisting of a stable toxin and an unstable antitoxin which mediate programmed cell death - although these gene-pairs are usually found on the bacterial main chromosome.	1.22214e-08
NC_019693.1|WP_015146638.1|281816_282203_+|BON-domain-containing-protein	gnl|CDD|335963	pfam04972, BON, BON domain. This domain is found in a family of osmotic shock protection proteins. It is also found in some Secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes.	0.000114824
NC_019693.1|WP_015146637.1|280756_281287_-|acetolactate-synthase-small-subunit	gnl|CDD|214364	CHL00100, ilvH, acetohydroxyacid synthase small subunit.	2.25711e-102

Protein sequences

>NC_019693.1|WP_015146625.1|271669_272542_+|VWA-domain-containing-protein
MIRSRRQIWQYPLFQIPLIFMVGCAIVAALSGLLGFGRPPVAVAIAIDYSGSTSGIVRQQEIQAVQSYINQNQTLKKPNAIQVFGFASDIRALTTDFTTDNEQIETQFNTSSQQPTLEQELGGGTNLNLAIQQTTNALSNIENRCRELLLVTDGIAPINDTIIQTAQAENVKINAVIVGGAQSDKLQQATRLTDGLYLSAEASNLELLFTQTFFRDFNSNLRWVMFWLSGAFIFLMWTLTLPLDRWLFQGIMGLDMTLAGQIALGNALFWTIVTLIAIWKGFGIPFGNPC
>NC_019693.1|WP_015146624.1|269980_271609_+|ABC-transporter-substrate-binding-protein
MSTPQSWICDGTPKNGQHYPNCSGPHPPQENHTPDCMICGLPREAMTGKKSPRGTKTVLSGGRGSNLPGLVAIALLLLLLGASAWYLFGRTRDPEIVESTSETVALSPGAANPLANVSQTAVNAELISQGEKILFNPGINFAQKAAGATAFSQDNWTEAVAQYQQAVQTDPNDPEAKIYFHNARAKQAGNPLTIAVVVPISASENSAKEVLRGVALQQERYNNAPQLPGRLLEVVIVNESEPGKAPSIAEDLIQSPNVLGVMGHGVDAASREAIARYERAQLAVLSPISTSISSTVPGESILQTISLAQKANELFANYLEGVGKTLATYAEQTVSSPAVVVFYNSDSPYSQQLKDAFKAALVQTPGQVVKEVDITQGGFNPATEVSDASQVGANVGVLALSKNKVQTAVAIAQANANAGTPLTLLGGDELYNPNILKDGDAAINGLVLAVPWRWQEGDAFASQATNIWQGRVSWRTATAYDTTQALANAITQQPTRAETSQLLQNGIAIAGTATDFSLFDRIPLVQAVPGTSAGFRYQFEPI
>NC_019693.1|WP_015146623.1|269421_269745_-|hypothetical-protein
MGLKIVQNFGGSFTLNPEAKSVLFELLNSPEFVHQIAEATQCHQVEFTELMFQPVPYSEQTPKGMPREFEPYHESDDYIIINVPPNFMFKAKIFNPSRICVVYRKLN
>NC_019693.1|WP_044194246.1|268782_269325_-|GIY-YIG-nuclease-family-protein
MSRMTDISPLSTLEFLPYLDDQGNCNSDFTGKVGVYAIFDGEKTLQYIGYSRDIVLSLKQHLMRKPNSCYWIKAQTIERPSRTILEEIRAAWIAENGQTPLGNGPDEGQWTQAIDVKPLMTDEEREKYEKSIDEFTQMKLLKQVSRRVEADLLAVLESRGLKEAIRFNPKLKESGLLDLK
>NC_019693.1|WP_015146621.1|266966_268712_-|protein-kinase
MNPVLLNNRYRILQELGMGGFGQTFLAEDTQMPSKRRCVIKQLKPVTGNPAIYQMVQERFAREAAVLEQLGDGNAQIPKLFAYFELEGQFYLVQEWIEGGTLTKKVQTLGTLSEAQVRSLLTKILPVLTYVHSFRIVHRDIKPDNIMLRPSNPGSFSPGEDVPFLIDFGAVKETMATAMSSSGGVTNSIAIGSPGFMSAEQAAGRPLYSSDLYSLGLTAIYMLTGKIPQEFPTDPATGEILWRSYAPTVSPGLGMVLDRAIRFNPCDRFPTAQEMLDALKPDVNSQVATVPIAPANRAAVPPSQVATVPIAPANRAAVPPSSPSPYRQSSPRPSGISPRAVGVAAAVLAVSFLIGFGIAQDKMSSDSPIATPPTNNPSSDSPPPTPTPPTDSQPTTPEPPPVVIPPSEPEPPPVVIPPSEPETPVDVIPPAEPEPPVDVIPPAEPETPVDVIPPAEPELPDSTPEPTEPVGDRPTPEESVIDYYANINDRNYSQSWNQLDTRFQTNQSGDYNTYTEWWNSVRRVTVNNVNVVASTPFSAIVDTSLTYIMEEDSRVSNETLRMSLIWDEETGTWAIEQTSRL
>NC_019693.1|WP_044194243.1|265290_266904_+|hypothetical-protein
MINSQANSNMELLGAGRSGEVFLLDSPHGKIARKIFYGDKITHLIHYFFFGAPNPYIWNEDALNCAYYRRRILQNLVQFWFGNHLTVANATDRGWNEESKSYQLDTEFSPGEAVALHHPFNHDKDWQVEVLVHRVMQPLQKWLIKSGFDGLVWQAGKGNPVALNNFLLTQNDRDNYQFVWIDLESGVPALIPLNFLTLFTFYLPKCFSHKRPLFDDVDMDRLNAYVETNRMGLEDTLGVKIYQEMVSDIEHMGYHQRNLKEMPRFQRSIFYQLKKGKITENEANRYLQNPWRWYLRELMRLGRKVPYKLLVRLPVKLFNFFTSIPYLGFIRGLFKVLFLRRYRLKVATDYVSRRLQRWTERNQLTDEESDYFSHHLHKDYSSEYLGDFGVHLGMKVFVKIFEYIISPLLYALGLINEGTLVLLIIFGGPISRTLYTSVRMFQAAGEGKEIPWVAFFMGLIPSLLGNIAYPCQMIYSASGSRGKLARFIVYDTFSRVGDKLPIWGGEDTLTEHYFNHGADRLVRWVSLLRQPFQRSHS
>NC_019693.1|WP_015146619.1|262627_264988_+|ATP-binding-cassette-domain-containing-protein
MTNPPGQQTVLNVNPYLELNNHGKVMRLELTDSRHVFGRDRSSGADLLVPPDWQIIGRAHAVLAKVGSEYHIYDGDGQRPSTNGLFIDRTRITPKEGFLMRDGTQIRIGQNPKDQILLTYINPASAGAPPTVRSLSLAGRSVVLGRDPSCNLQLDAPIVSRRHAVIDNYTITDYSTNGVFVNGQRVKTSQRLTDGATIRIGPFTLLLRGDELQVLDRGNQIRLDAESLVREVKDGQKVKRLLNQVTLAIEPGQFVALVGGSGTGKSTLMRTLLGIDPTTQGRVYINGDDLRTTFNIYRTQIGYVPQDDIIHGQLTVREVLSYAAKLRLPPDTDVEAVVTKTLAEIEMGDRETVPVNQLSGGQRKRVSIGVELLADPKLFFLDEPTSGLDPGLDKKMMQLLRKLADQGRTIVLVTHATANIKLCDRVVFMGRGGYPCYFGPPDEAFQFFRINSGDFADIYNELEQGEEHAAQWANVFRQSPYYRNYVENHLSTGKGSAVAPPSQVKPSGFQQLSLLTQRYFKLVQRDPINLGLVLLTAPIGISLITLAIRDQDPLIGEPEATLAPLALRVLFVFTCAAIWIGLSTSLQEIVKEWAIYMRERLVNLGLFPYLGSKLLILGGLALLQTVLMVAAILIGFKSPQPELIPWAIGVAISTVLTLFTSMSLGLLVSALVKNSSQANSSLPLLLLPQIIFAGVLFSMEGVGRVISWVMLSRWSVGAYGSLVNVNAMVPEATVLPDGTTMPLPFEPTAIYDPTWENLGLNWGMLLLHATVYLGLTLWVQKRKDIF
>NC_019693.1|WP_083896724.1|260483_262067_-|DUF4101-domain-containing-protein
MTPTKLNNRYQVIRDIGAGGFGKTFLVEDTQMPTQRRCVAKQLKPVTTNPQIFQLLQDRFAREAAILEELGEGNTQIPRLYAYFEEEGQFYLVQEWIEGETLTHRVQNSSKLSESSVREILVSLLRVLEFVHSQRIVHRDIKPDNIILRNSDGTPVLIDFGAVKETMGTVMNSSGQGNSSIVIGTPGFMPSEQAAGRPVYSSDLYSLGLTAIFLLTEKWPQELQMNHDTGEIVWRQYAPRISPSLATVLDKAIMSHPRDRFHSAREMLDALEGRNSSSPAVAVAAVPPPMASVPPVANGVPVTTVSTPPPSYQAQTVFSPSTVQPADTTRSSGMGDWQKAIVIGGIIGAFVLIGLWITRPQPTPTTATASSETDDSGTSPNPETSSNFAPVPSQPMPSNPTITSQEAVALITKWLDAKDRMFAPPYSRQLADELTTGALYADLIKHDGPIAWLQNNNAYYQYGVKKVESVERFAADGDRASLEVIVIEDRTLYKNGRIDPEQSKFSTDKVRYTLQLVNGTWKIADYQ
>NC_019693.1|WP_015146617.1|258993_260427_-|hypothetical-protein
MGQPTGSKFPKHQQQIHQLENELDRASQIIEELRRENIHLKHQNAQLQERAINQKTVLQRESAVPSFATSPKTRLQNDVLHEKPNQKTRLEQLSKLPFPVKVAIVVLVIVIAGLATMQLKNWRPRGYSAPDGKPPLSPSETLSIPRSSSSPESASDSLSILPQSNRLEKIKLSYNINKAPRFQSSEQLQLIIEESIDLVASKGLPTAAFSISLIDAKTGEMTGYQDKTLRYPASLSKLFWMVALYAQVEKQLLPEDTVFYTEKCLTNICKMAQKSDNDAASRILDLLTDTTSQPQNSENYDQWLNQRQWVNRFFQEAGYQDINIGQKNFPIPYLKLEEPQGFELRMRGNPENPLRNKMSSEQVARLMYEIVNGQAVSQKATENMMQLLRRDLRPEVWQQEQYNSVQGFLSELLPRSEVYVASKVGWTSTSRQEVAYIATEDGKSAYILAIFGDDPAFANDWKIFPEISLHIYRRMNE
>NC_019693.1|WP_015146616.1|257411_258902_-|serine/threonine-protein-kinase
MNKLTLLNNRYRIIRELGSGGFGETFIAEDTQMPSERRCVVKQLKPVTANPQIFQLINERFAREAAILEALGEGNRQIPRLYAYFEEQSQFYLVQEWIEGETLTNRVANQGKLSESSVREILLSLLPVLEFVHSQGMVHRDIKPDNIMLHRGDGIPILIDFGAVKETMGTVMNSSGNGNSSIVIGTPGFMPSEQAAGRPLFSSDLYSLGLTAIFLLTEKWPQELQSDSRTGEIIWRQYAPRISPGLATVLDKVIMSHPRDRFHSAREMLDALNPSPLPGYAIPPTISSPPPVHSVPPVSVGVASTPTPLPVDQSSSLGDWQKAAIMGTIIGVFVFVGLWISRPQPATTSSNVIPTEPSPPPEAVNAVPEVERNSPQAQPTPDPIRLIEQPNPKQFIRNHYANLNQRQYDTTWSKLSPNFKSKASTFADYVDWWESVAEIRVLSVRSIAQTEREAIIDVQLQYLMHDGIIVNDPKSRINLVWDNRQQTWLFEDKFEP
>NC_019693.1|WP_015146628.1|273511_274429_-|hypothetical-protein
MTRFVYDQFAKQYLTELLSPFGEVEASRAIAAEVREVDVIFSPASDHPPEVAILGLLGRLATTAAIFEPFRNAIQPGDIRSCLSKLFELYNEFDRQANRENTRLNEAQLPHLWILSPTVSQAVLSGFKAELDLENWGEGVYFLGRSFKTGIVVIHQLPKTPETLWLRMLGKGNVQKQAIAELRQLPEDNPFRVQTLELLYNLLTILEVRQDLETEDQSLIMELSPLYLERLENANQRGIQQGIQQGFEQGQRRIVEGMLQAKFGEVDAELSAIIESLLLIPPVEISRLIAQLSREELLARVRNTN
>NC_019693.1|WP_015146630.1|274896_275538_+|hypothetical-protein
MPIYRQLPENHDIDNRLNSLKNSGLLVGSDAIIDKKLNDLANEVKLGQIGAKGEITFLERQIFSLGRSVEIIPESVQKNVKIPDYAVYLNQGETLKSEITEIKTTVKTTNVSASAGWDQWIKKKIRQANKQLKKSGLTYGIPGSLEMQLYEDAEKDFSAILFNEPETVAGWILQDFRSNQMRSLRRVAIYGNGELLVEFIRTEDHQIIKTFPE
>NC_019693.1|WP_015146631.1|275567_276395_+|hypothetical-protein
MNNYQNVQTTWRRGSGLIDWTYNLFVESTLEEFLPNSSLTPLSIFGGRGLRDLPDNLVVKSPLEKFLNSPSNSPLPMGKRLGRLLLTDPSIRRLWIVERIERLVKTLDDFARVEDVTVDTRSCGEETFVIEDWQGTQSRLKLRNWLTKTDDVVNIDFTLTLQCVTPGDRDIPEELAIKSGGNISIFVELDDDGELDTTTPSPIWLTFGLDVDIYAPLSWGEQRDNTKLAQLNGSRLSAFLHRLEEDIPGEFLGVDAPDYQDLVNRYGFLGVSHRP
>NC_019693.1|WP_015146632.1|276757_276988_+|addiction-module-protein
MLTLDQLISESMALSDADKAILIDKIMESMTDSLDQDLLREGMQKAQARIAEIESGKVQTIPGDIALAQIRQQFGP
>NC_019693.1|WP_015146633.1|276984_277275_+|plasmid-stabilization-system-protein
MKYEFHPTALQEYAEAVQFFAQYDKHQDFIDTIELSIFRIVSAPDRWPIIEGQIRRYLTPKFSYAIFYRVYSDRIVIAAISSCRRDPDYWKGRLES
>NC_019693.1|WP_015146634.1|277412_278597_-|hypothetical-protein
MSHKVSLLDKLSLRGLEIAPSQVYGGIRLVPLLRSHFRPDLRLRQRRYREDITSVAVEGKMQDPEMSYISYIPHGLVLSWDEGTTDVAFGTQLQGRDGKVVDYGCAKVRLMHRMAKRESENSLRFLPLHLAMEGFLGMFFAGPAIAWQEYSRQVLSEGLGSRGEMSYSGRAVGGFADALRVFEIHENQVGVLVFVADAIASAFIVPNPQDYRALHSNLLEDFYGELIYHYGLLYDTPLPMDVAIEADKIQNLEELRKAVAEMRSQWGKFHGFMATNLLQRELNSQRVYTAGPFGLQRFITELEPKGENHIGEAIISETGEIQYLKTYRLSAAQTRRVYLLSQLAKCDWNLEITARELGQTRDELALRLDKAGFGYLLKQNVLEVARKNLKKGRG
>NC_019693.1|WP_015146635.1|278694_280122_-|hypothetical-protein
MDAQWSKQVSQIERQDLVMFINACLSCTGQREFYNDEYGTRVSLDFLHDYILGNYRLLYARTLAAGINHFNRAQIILKLLAAGRDTPPEHRQEEGALIAAALNQLPPQRAWKVLAEIRRRGINNRRSRAVVRDYIQSRRDISFQAVKYRAKLRGVAIHNHLKLETELAAFLFDPTKIKAYQTDIFEDFRKAKYDQEAIYALPLTVAEGFAAQHGIKRETFLDRIQEQMTPGEKLRLQKAANREKQEIPLDLGQMPLTKLALYVLSLSRAERGDRFAILDDALDSAARRTLQRSPLHLGRVATVLDCSYSASGSSEKRRRPLGIALAAHYLLKAAAQEYRAFWTIPGTEALLVTPRGQTDLATPVLDALEWGADLVVIVSDGWENDPPRGAAQVLEIYRTKLDNQGRTAIVHCNPVFDSDDFLLRSLTPAIPTVGLREAEDLPTLLGFARFAEGTAELADLEAYLGAKVRQLLGEE
>NC_019693.1|WP_015146637.1|280756_281287_-|acetolactate-synthase-small-subunit
MKHTLSVLVEDEAGVLSRIAGLFARRGFNIESLAVGPAEQLGISRITMVVPGDDRVIEQLTKQLYKLINVIKVQDITETPCVERELMLLKVNANSNNRPEIVELAQIFRARVVDVAEDSLIIEVVGDPGKMVAIVQVLAKFGIREISRTGKIALTRESGVNTEFLKSLEAKMFPIS
>NC_019693.1|WP_015146638.1|281816_282203_+|BON-domain-containing-protein
MGLLQKLFNLGKPDKSKETTVQAPPASNPSAPAQSYSVPAAPQKPDIPPERLGLNGEYDDSGLAKRVALALDENPSTADFERLWIAQTGSTVVFKGEIPSQADLDRVVGIARGVYGAKDVKTTEVKVG
>NC_019693.1|WP_015146639.1|282498_283938_-|cation:proton-antiporter
MAETLTLVNSLTTTLFNSFLDQTLPLLATAGTEVAPAAHSVKVDEAIVVAGVLLSLVVIYLASKIGGEICSRINLPPVLGDLVGGVIVGVSVLKLIVFPEGGEDGSSSLIMSLLQRTTSLEPEAIVATFAAQSEVIAILAELGVIILLFEIGLESELKELIKYGPQAAVVAVIGVVLPFGAGTLGLISLFHVATIPAIFAGAALTATSIGITAKVLAEIGRLGDKEGQIIIGAAVLDDILGIIVLAVVASLVKTGEIEVTNIAYLIVSAGAFLIGVIILGRFLSPYYVAFVKELKTRGPLLITALIIAFVLSYVGAAIRLEAILGAFAAGLVLGETEKQQELEEQVVPLADFFVPIFFVVVGAKTNLGVLNPAIPSNREGLIIAAFLIVVAIIGKVIAGFAVFGQPGINRLAIGIGMVPRGEVGLVFAGVGVASGALSPSLEAAIIMMVILTTFVAPPLLRVVFKDPLPETESAGSAPK

Crispr_ID: NC_019693_8

• CRISPR_ID: NC_019693_8
• CRISPR_location: 291856-291950
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_8

Consensus_repeat	Method
CAAGAAACCCTGATTTTTCGTCATTAAATT	CRISPRCasFinder

spacers of NC_019693_8

>8.1|291886|35|NC_019693|CRISPRCasFinder
TACCTCTTGTAGGGGCGCGAGAGTGATCGCCTGTC

CRISPR arrays and Neighbor proteins around NC_019693_8

CRISPR arrays

The CRISPR arrays of NC_019693_8

>merge|NC_019693|8|291856-291950|CRISPRCasFinder
CAAGAAACCCTGATTTTTCGTCATTAAATTTACCTCTTGTAGGGGCGCGAGAGTGATCGCCTGTCCAAGAAACCCTGATTTTTCGTCATTAAATT

>NC_019693|8|8|291856-291950|CRISPRCasFinder
CAAGAAACCCTGATTTTTCGTCATTAAATT	TACCTCTTGTAGGGGCGCGAGAGTGATCGCCTGTC
CAAGAAACCCTGATTTTTCGTCATTAAATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015146640.1|284228_285041_-|carbon-nitrogen-hydrolase-family-protein	unknown	unknown	gnl|CDD|143596
NC_019693.1|WP_015146652.1|296239_296713_-|hypothetical-protein	unknown	unknown	gnl|CDD|374405
NC_019693.1|WP_015146651.1|295392_296184_+|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl|CDD|223257
NC_019693.1|WP_015146638.1|281816_282203_+|BON-domain-containing-protein	unknown	unknown	gnl|CDD|335963
NC_019693.1|WP_015146639.1|282498_283938_-|cation:proton-antiporter	unknown	unknown	gnl|CDD|223551
NC_019693.1|WP_015146653.1|296959_299323_-|C39-family-peptidase	unknown	unknown	gnl|CDD|379241
NC_019693.1|WP_015146654.1|299841_300276_-|peroxiredoxin	unknown	unknown	gnl|CDD|239315
NC_019693.1|WP_015146655.1|300321_300762_-|peroxiredoxin	unknown	unknown	gnl|CDD|239315
NC_019693.1|WP_015146646.1|290854_291328_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379228
NC_019693.1|WP_156823701.1|294890_295052_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146645.1|289845_290910_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_019693.1|WP_015146644.1|289237_289849_+|L-threonylcarbamoyladenylate-synthase	unknown	unknown	gnl|CDD|223088
NC_019693.1|WP_015146641.1|285912_286131_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044196233.1|287232_288003_+|hypothetical-protein	unknown	unknown	gnl|CDD|273383
NC_019693.1|WP_015146649.1|293954_294338_-|50S-ribosomal-protein-L21	unknown	unknown	gnl|CDD|177014
NC_019693.1|WP_015146647.1|292096_293086_-|porphobilinogen-synthase	unknown	unknown	gnl|CDD|236450
NC_019693.1|WP_015146648.1|293524_293812_-|50S-ribosomal-protein-L27	unknown	unknown	gnl|CDD|235464
NC_019693.1|WP_015146650.1|294540_294870_-|30S-ribosomal-protein-S6	unknown	unknown	gnl|CDD|275387
NC_019693.1|WP_015146643.1|288284_289214_+|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	unknown	unknown	gnl|CDD|236467
NC_019693.1|WP_015146637.1|280756_281287_-|acetolactate-synthase-small-subunit	unknown	unknown	gnl|CDD|214364

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015146640.1|284228_285041_-|carbon-nitrogen-hydrolase-family-protein	gnl|CDD|143596	cd07572, nit, Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases). This subgroup includes mammalian Nit1 and Nit2, the Nit1-like domain of the invertebrate NitFhit, and various uncharacterized bacterial and archaeal Nit-like proteins. Nit1 and Nit2 are candidate tumor suppressor proteins. In NitFhit, the Nit1-like domain is encoded as a fusion protein with the non-homologous tumor suppressor, fragile histidine triad (Fhit). Mammalian Nit1 and Fhit may affect distinct signal pathways, and both may participate in DNA damage-induced apoptosis. Nit1 is a negative regulator in T cells. Overexpression of Nit2 in HeLa cells leads to a suppression of cell growth through cell cycle arrest in G2. These Nit proteins and the Nit1-like domain of NitFhit belong to a larger nitrilase superfamily comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13), this subgroup corresponds to class 10.	9.17439e-131
NC_019693.1|WP_015146652.1|296239_296713_-|hypothetical-protein	gnl|CDD|374405	pfam16166, TIC20, Chloroplast import apparatus Tic20-like. Chloroplast function requires the import of nuclear encoded proteins from the cytoplasm across the chloroplast double membrane. This is accomplished by two protein complexes, the Toc complex located at the outer membrane and the Tic complex located at the inner membrane. The Toc complex recognizes specific proteins by a cleavable N-terminal sequence and is primarily responsible for translocation through the outer membrane, while the Tic complex translocates the protein through the inner membrane. This entry represents Tic20, a core member of the Tic complex. This protein is deeply embedded in the inner envelope membrane and is thought to function as a protein- conducting component of the Tic complex.	1.20613e-19
NC_019693.1|WP_015146651.1|295392_296184_+|fumarylacetoacetate-hydrolase-family-protein	gnl|CDD|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	4.07517e-98
NC_019693.1|WP_015146638.1|281816_282203_+|BON-domain-containing-protein	gnl|CDD|335963	pfam04972, BON, BON domain. This domain is found in a family of osmotic shock protection proteins. It is also found in some Secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes.	0.000114824
NC_019693.1|WP_015146648.1|293524_293812_-|50S-ribosomal-protein-L27	gnl|CDD|235464	PRK05435, rpmA, 50S ribosomal protein L27; Validated.	1.93822e-55
NC_019693.1|WP_015146653.1|296959_299323_-|C39-family-peptidase	gnl|CDD|379241	pfam13529, Peptidase_C39_2, Peptidase_C39 like family.	2.00064e-16
NC_019693.1|WP_015146654.1|299841_300276_-|peroxiredoxin	gnl|CDD|239315	cd03017, PRX_BCP, Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing and detoxifying hydroperoxides. The protein was named BCP based on its electrophoretic mobility before its function was known. BCP shows substrate selectivity toward fatty acid hydroperoxides rather than hydrogen peroxide or alkyl hydroperoxides. BCP contains the peroxidatic cysteine but appears not to possess a resolving cysteine (some sequences, not all, contain a second cysteine but its role is still unknown). Unlike other PRXs, BCP exists as a monomer. The plant homolog of BCP is PRX Q, which is expressed only in leaves and is cellularly localized in the chloroplasts and the guard cells of stomata. Also included in this subfamily is the fungal nuclear protein, Dot5p (for disrupter of telomere silencing protein 5), which functions as an alkyl-hydroperoxide reductase during post-diauxic growth.	3.81863e-64
NC_019693.1|WP_015146655.1|300321_300762_-|peroxiredoxin	gnl|CDD|239315	cd03017, PRX_BCP, Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing and detoxifying hydroperoxides. The protein was named BCP based on its electrophoretic mobility before its function was known. BCP shows substrate selectivity toward fatty acid hydroperoxides rather than hydrogen peroxide or alkyl hydroperoxides. BCP contains the peroxidatic cysteine but appears not to possess a resolving cysteine (some sequences, not all, contain a second cysteine but its role is still unknown). Unlike other PRXs, BCP exists as a monomer. The plant homolog of BCP is PRX Q, which is expressed only in leaves and is cellularly localized in the chloroplasts and the guard cells of stomata. Also included in this subfamily is the fungal nuclear protein, Dot5p (for disrupter of telomere silencing protein 5), which functions as an alkyl-hydroperoxide reductase during post-diauxic growth.	3.96432e-62
NC_019693.1|WP_015146646.1|290854_291328_-|GNAT-family-N-acetyltransferase	gnl|CDD|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.09303e-13
NC_019693.1|WP_015146645.1|289845_290910_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	4.05352e-19
NC_019693.1|WP_015146644.1|289237_289849_+|L-threonylcarbamoyladenylate-synthase	gnl|CDD|223088	COG0009, SUA5, Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis].	2.24962e-52
NC_019693.1|WP_015146639.1|282498_283938_-|cation:proton-antiporter	gnl|CDD|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	1.54853e-60
NC_019693.1|WP_044196233.1|287232_288003_+|hypothetical-protein	gnl|CDD|273383	TIGR00995, Tic22-like_protein, chloroplast protein import component, Tic22 family. Two families of proteins are involved in the chloroplast envelope import appartus.They are the three proteins of the outer membrane (TOC) and four proteins in the inner membrane (TIC). This family is specific for the Tic22 protein. [Transport and binding proteins, Amino acids, peptides and amines].	1.01307e-40
NC_019693.1|WP_015146649.1|293954_294338_-|50S-ribosomal-protein-L21	gnl|CDD|177014	CHL00075, rpl21, ribosomal protein L21.	2.40557e-57
NC_019693.1|WP_015146647.1|292096_293086_-|porphobilinogen-synthase	gnl|CDD|236450	PRK09283, PRK09283, porphobilinogen synthase.	0
NC_019693.1|WP_015146650.1|294540_294870_-|30S-ribosomal-protein-S6	gnl|CDD|275387	cd15487, bS6_chloro_cyano, 30S ribosomal protein S6 of chloroplasts and cyanobacteria. bS6 is one of the components of the small subunit of the prokaryotic ribosome, a ribonucleoprotein organelle that decodes the genetic information in messenger RNA and forms peptide bonds to synthesize the corresponding polypeptides. Mitochondrial and chloroplastic ribosomes are similar to bacterial ribosomes. Ribosomes consist of a large and a small subunit, which assemble during the initiation stage of protein synthesis. Prokaryotic ribosomes consist of three molecules of RNA and more than 50 proteins. The small subunits of bacterial and eukaryotic ribosomes have the same overall shapes (with structural elements described as head, body, platform, beak and shoulder). The bacterial ribosomal protein S6 is important for the assembly of the central domain of the small subunit via heterodimerization with ribosomal protein S18.	1.8533e-50
NC_019693.1|WP_015146643.1|288284_289214_+|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	gnl|CDD|236467	PRK09328, PRK09328, N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional.	9.72876e-96
NC_019693.1|WP_015146637.1|280756_281287_-|acetolactate-synthase-small-subunit	gnl|CDD|214364	CHL00100, ilvH, acetohydroxyacid synthase small subunit.	2.25711e-102

Protein sequences

>NC_019693.1|WP_015146646.1|290854_291328_-|GNAT-family-N-acetyltransferase
MDCSHIQFRDRKEDVDIQQLQRLFELTAFWARERKIEDLAIAIANSDPVITVWEGERLIGLARATSDGIYRATIWDVIIHPEYQGVGLGRKLVETLLSHPRMNRVERVYLMTTHQQRFYERIGFEENSTTTMVLYNNQNFTEELKTREVRVEASIEA
>NC_019693.1|WP_015146645.1|289845_290910_+|HAMP-domain-containing-histidine-kinase
MSGDAMFLLSAISVQELGWNFGQTMDWIYWISGIGALGFGFGSGWLMRSRYRPDQSIKFPSSQGKTLGDSHLSTRLKQTQLDYLLTRQMCQFKAGFLSRISHELRSPLNSLIGVHQLILSDLCDNPAEEREFLVQANNSVHKMIQMLDRIIEVSRIEEGRNPLKLEILNLADVFEEVHYLTELQAANRNISLHISQPDPKISVRADQRCLTQVLVTFIDLAINPVGNGRIGISAKVFPRSDSTRSLPESTPGKTQGDSVIISIDLPLPPHCFSEPLDFLQLQQNRKESTPETDVDLSPGTILMMNQSILELMGGHLEIVEAPPTSEELRGGEDSEITRLQCSLPRALRESSVLP
>NC_019693.1|WP_015146644.1|289237_289849_+|L-threonylcarbamoyladenylate-synthase
MTAVSEQVLIEAALAGQVVSFPTDTVPALAVLPSRAESIFAVKQRSLDKPLILMGATEADLWPFVRSTQRELQIWQGVANRHWPGALTLVLPASAAVPSVINPVDPSTIGIRVPDQAIARRILAQTGPLATTSANLSGEPPLQTMAEISLRFPQVVTLEWAQSEPNPTASGVPSTVAKWTGQSWEILRQGVIQLDSNSKDRGR
>NC_019693.1|WP_015146643.1|288284_289214_+|peptide-chain-release-factor-N(5)-glutamine-methyltransferase
MSRSSDPAVSGLELWQWRQEARAAAIAANVPVEELDWLLLSVSDLDKLALRLDSYKGRGHIPLNRPLAQLKEQWQQRIQNRVPVQYLAGVTPWRNFSLGVSRAVLIPRPETEWAIDLALRSAQSGSRPHLDTPLTEGDWADLGTGSGAIALGLAEVLPNVTLHAVDRSEDALAIAQKNALNLGYSDRIQFYCGSWFKPLHPFQGLNRFRGIVSNPPYIPTAMLGELEPEVAHHEPAIALDGGPDGLDCIRHLIATAPSYLCPGGILLLEMMAGQAPAVTELLQDQGSYTQIEIFSDLAGIERFARAYRS
>NC_019693.1|WP_044196233.1|287232_288003_+|hypothetical-protein
MKSLVRWSASLGLIGSVLLGQLLPGMNRAIALPAEEIMKKLESVLVFTITNAEGTPLIASVTNDEREASIASFFMSQRDAEQFVQKIEQQNPELAGNTQVVPVSLAKVYELEQANANNPERLEFAFIPVQQQVQFAAEELQQEGQEIPQSNGMPLFNGVPLFYATIGPEQGYLTIEQNGEQLIPIFFNREQLESMLTRVREQQPDLAPSIDVRVSNLDKVIEELENNDDPAVTKIVLVPSTETLEYLQSLPQPAQP
>NC_019693.1|WP_015146641.1|285912_286131_+|hypothetical-protein
MNVISQIAKQALATGYLTLEAEERLRLLLQQTEYGLEDFQAFMLLQKEAMKGRVRQESRELWRSHQHITAAV
>NC_019693.1|WP_015146640.1|284228_285041_-|carbon-nitrogen-hydrolase-family-protein
MKSYLAAAIQMTSVPDLAKNLAQAEELIDLAVRRGVELIGLPENFSFLGEESEKVHQAEAIAVESEKFIKTMAQRYQVTILGGGFPVPVNQGQVYNTAILVEPNGQEVARYQKVHLFDVNVPDGNTYQESSTVKAGELLPPIYQSEKLGTLGLSVCYDVRFPELYRHLSYKGAEVLFIPAAFTAYTGKDHWQILLQARAIENTCYAIAPAQTGRHYGTRHSHGHALIIDPWGAILADAGDQPGVAIAEISPSRLEQVRRQMPSLQHRVFI
>NC_019693.1|WP_015146639.1|282498_283938_-|cation:proton-antiporter
MAETLTLVNSLTTTLFNSFLDQTLPLLATAGTEVAPAAHSVKVDEAIVVAGVLLSLVVIYLASKIGGEICSRINLPPVLGDLVGGVIVGVSVLKLIVFPEGGEDGSSSLIMSLLQRTTSLEPEAIVATFAAQSEVIAILAELGVIILLFEIGLESELKELIKYGPQAAVVAVIGVVLPFGAGTLGLISLFHVATIPAIFAGAALTATSIGITAKVLAEIGRLGDKEGQIIIGAAVLDDILGIIVLAVVASLVKTGEIEVTNIAYLIVSAGAFLIGVIILGRFLSPYYVAFVKELKTRGPLLITALIIAFVLSYVGAAIRLEAILGAFAAGLVLGETEKQQELEEQVVPLADFFVPIFFVVVGAKTNLGVLNPAIPSNREGLIIAAFLIVVAIIGKVIAGFAVFGQPGINRLAIGIGMVPRGEVGLVFAGVGVASGALSPSLEAAIIMMVILTTFVAPPLLRVVFKDPLPETESAGSAPK
>NC_019693.1|WP_015146638.1|281816_282203_+|BON-domain-containing-protein
MGLLQKLFNLGKPDKSKETTVQAPPASNPSAPAQSYSVPAAPQKPDIPPERLGLNGEYDDSGLAKRVALALDENPSTADFERLWIAQTGSTVVFKGEIPSQADLDRVVGIARGVYGAKDVKTTEVKVG
>NC_019693.1|WP_015146637.1|280756_281287_-|acetolactate-synthase-small-subunit
MKHTLSVLVEDEAGVLSRIAGLFARRGFNIESLAVGPAEQLGISRITMVVPGDDRVIEQLTKQLYKLINVIKVQDITETPCVERELMLLKVNANSNNRPEIVELAQIFRARVVDVAEDSLIIEVVGDPGKMVAIVQVLAKFGIREISRTGKIALTRESGVNTEFLKSLEAKMFPIS
>NC_019693.1|WP_015146647.1|292096_293086_-|porphobilinogen-synthase
MFPTHRPRRLRQHPQLRRMVRENLLTTSDLIYPLFAVPGESVAKEVSSMPGVYQLSVDKIVEEAKEVYDLGIPAIILFGIPEDKDTDATGAWHDCGIVQKATAAVKAAVPELLVIVDTCLCEYTSHGHCGYLEVGDLMGRVLNDPTLELLKKTAIAQANAGADIIAPSGMMDGFVQAIRSGLDGAGFEDMPILSYAAKYASAYYGPFRDAADSSPQFGDRRTYQMDPANGREALTEIELDIEEGADMLMVKPALAYMDIIWRVKQASHLPVAAYNVSGEYAMVKAAALNGWIDEERVVLETLTGFKRAGADLILTYHAKDAARWLANQS
>NC_019693.1|WP_015146648.1|293524_293812_-|50S-ribosomal-protein-L27
MAHKKGTGSTRNGRDSNAQRLGVKRYGGQVVRAGNILVRQRGTKFHPGQNVGRGSDDTLFALIDGVVTFERKGKSGKKISVYAVAATAEPVAVEA
>NC_019693.1|WP_015146649.1|293954_294338_-|50S-ribosomal-protein-L21
MTYAIIETGGKQLRVEPGRFYDIELLPVDAEESITLENLLLIQHDDQVHIGQPFVEGATLQATVMQHYRGRKVIVYKMKPKKKTRKKRGHRQEITRLMIDSISLNGAVLASAENNTPASSTPSTEAE
>NC_019693.1|WP_015146650.1|294540_294870_-|30S-ribosomal-protein-S6
MRYIYETMYILRPDLGEELTDGAIAKYQGLLQENGVTSVETQHRGKRRLAYEIGKHRDGIYIQMNYECDGSQVAPLERAMRLSEEVIRYLTIKQPVREVEEEEEVEATA
>NC_019693.1|WP_156823701.1|294890_295052_-|hypothetical-protein
MRVKSRRKRKTSLNLAMPCFFTTMAEQKPVLARSAGVREASVQENRAQSEEAI
>NC_019693.1|WP_015146651.1|295392_296184_+|fumarylacetoacetate-hydrolase-family-protein
MAQRYVRIQTPEGRIYYGLLQLSRGVQLLDAPPWLKGQPTERFLEPETYRLLAPCVPSKIVAVGKNYADHAAEMGTPVPKEPLLFLKPPTAVIADGDEIAYPPQSERVDYEGELALVIGERCVDCTPEEATGKIWGYTIANDVTARDLQKKDGQWTRGKGFDTFCPLGPWIVREVSPGAGLQTFVNDASEPVQSSIIDDMVFPPDVLVSYISQVMTLLPGDVVLTGTPEGIGPLQVGDRVRVEIEGIGSLENTVRQRLTPLAL
>NC_019693.1|WP_015146652.1|296239_296713_-|hypothetical-protein
MSWNSSTSVPDRIFASLPYLLPLIVGVQFGMFLFREFPVLSLFFVPLQPLLSLYYSIPFAGLIIFFVLLFAVVRNNNISRFIRFNTMQAILLNIILAITGLVVQLLGNALPILAVQTLFNMLFLGTVAAVGYSVVQSLLGRYAEIPTLSEAVHMQVR
>NC_019693.1|WP_015146653.1|296959_299323_-|C39-family-peptidase
MSLGNSFTFKILHDTFLKVSTASSSSLTATQKVSVKAGETVEIKSYELSEGHFRVQLAQGIAPVGETGYFYEKHIELLPNLVNCTFNSGNSVEPPPGFGLLTILETTKIKAKPEDSSQLSDREQTELQAGQTFLITGHACVSSHFLVSLSEEIPGFGSRGYLYHPHVSLKKDDKAIDYDANAITLTILQTNPFKKQPIDSSQLPPEELYSLKSGEIYGVASYAMEAGHLKISLTENLPQFGNTGYLFPDFVQLNRGNSPISTGFGLSYQGPTEVLVEKPVILTGTYDPQKIATVTLSAEDKFSLPVQLNPSAGTWQVNLNNGFSGAGARWLRLKGTNSQGQLIGSDVINITVTTDSATVGEALTLKIQQDTFFKVSPVDSASLSNQQKVLIKAGMTVQVSRYGLLDGHLKVTLDSPIQPVGEFGYFYEGHVQLSKGSKVFNFNIEDVQISGTPAQMLVTKTTLIKAQPVDSANLSAAQKAELLLGKTLGITGYASTSGHFRVTLSESIPGFGNVGYVYWQHVQIKNRNQVVSYDSDALTATIRETTVFKKQPVDAARLSATDKVTLPLGRVYGVASYAIESGHLKASLTEEFPGFGNTGFLFPGHLLMQRGGRTFDPVPNHIELNVPYFSQRDNPRYSWSTCNVTSIAMVFHYYGIRSKRGGQLEDELLQWCFNYAGVGSQTDHSVLSAMVRAYGFKHRFSTTSTWSDVKNELINRRPVVIAGYFTATGHIITIMGYNRQGYIVQDPWGDALTGYSHTEGRRLIYPYSYMDRVCGPEGNVWIHSIQK
>NC_019693.1|WP_015146654.1|299841_300276_-|peroxiredoxin
MTLAVGTIAPDFTVKDTNGNTVTLSQFKGKTVVLYFYPKDDTPGCTKEAQGFRDSYSDYQSKEMVVLGVSRDDEASHKLFTEKYGLPFQLLADVDGALTKAYDVDGGSYSKRVTYVIDSEGKIAQVYDQVNTSSHAQDILAAVS
>NC_019693.1|WP_015146655.1|300321_300762_-|peroxiredoxin
MTLPVGAAAPAFTARDTNGNLVKLSDFAGKPLVLYFYPKDDTPGCTKEACSFRDSYSEFRNKNVAILGVSRDDEVSHQQFAQKFSLPFPLLADTDGAITKAYDVEKGEKAKRVTYIIDGIGKISQVYEGDNLNTETHGPDILAALY

Crispr_ID: NC_019693_9

• CRISPR_ID: NC_019693_9
• CRISPR_location: 475830-476937
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 14 spacers
• Cas_protein_info: cas2,csx1

Consensus repeat of NC_019693_9

Consensus_repeat	Method
GTTTCCGTCCCCTTGCGGGGAATTGATAGGAATT	CRISPRCasFinder
GTTTCCGTCCCCTTGCGGGGAATTGATAGGAATT	CRT
GTTTCCGTCCCCTTGCGGGGAATTGATAGGAATT	PILER-CR

spacers of NC_019693_9

>9.1|475864|47|NC_019693|CRISPRCasFinder,CRT
CACATAGTTATGGAATGGTTAGTCGAAGCGTTCTGTATGGCAATTTT
>9.2|475945|47|NC_019693|CRISPRCasFinder,CRT
AACGCTCGGGAACGGGAAAATCTGGGTGGGGTAGTGCAAGTGACCCT
>9.3|476026|44|NC_019693|CRISPRCasFinder,CRT
TACGTGGAATGGACGCCTTCAACGAGGTGGAGTTAACATATGAA
>9.4|476104|40|NC_019693|CRISPRCasFinder,CRT
CACGTATTACTAAATGGATTAAAGATGCTTTCAATCCTGA
>9.5|476178|38|NC_019693|CRISPRCasFinder,CRT
CACGATGAGGATAAATTCATCAACCATTGCCACAGTGA
>9.6|476250|40|NC_019693|CRISPRCasFinder,CRT
CACCTGAACATCCGTTTCTAAGCGCTCCTCGTAAGAATGT
>9.7|476324|45|NC_019693|CRISPRCasFinder,CRT
CACTGCGATCGCCTGTGAGACTCCTGAACTTATCTCTAAGGTCGT
>9.8|476403|44|NC_019693|CRISPRCasFinder,CRT
AACAATGTTGAAATAGCCTATAGAAATGGTACTTGGTAGTATGG
>9.9|476481|41|NC_019693|CRISPRCasFinder,CRT
CACCCAGGAATAAGCTAATAAGTTTACTTTATGCGTTAAGA
>9.10|476556|43|NC_019693|CRISPRCasFinder,CRT
CACCTTGGGTGACCAACGGTTAAGGATAGCAGCAAGGGCTGTT
>9.11|476633|43|NC_019693|CRISPRCasFinder,CRT
CACTTCCATTAAGTAACCAATCACCTTATAAGGAGAATGATTA
>9.12|476710|44|NC_019693|CRISPRCasFinder,CRT
AACCTGCTAGATGGATGGACCCTCATTTCCACGTCCAAGTAATT
>9.13|476788|39|NC_019693|CRISPRCasFinder,CRT
CACCTTACTTCTTAATTCAAGAATGTGACTTCTATCTAA
>9.14|476861|43|NC_019693|CRISPRCasFinder,CRT
CACTAGGTATTGACCCTAACTTTCCTGATAAAGCCCTTATGAC
>9.15|475865|47|NC_019693|PILER-CR
CACATAGTTATGGAATGGTTAGTCGAAGCGTTCTGTATGGCAATTTT
>9.16|475946|47|NC_019693|PILER-CR
AACGCTCGGGAACGGGAAAATCTGGGTGGGGTAGTGCAAGTGACCCT
>9.17|476027|44|NC_019693|PILER-CR
TACGTGGAATGGACGCCTTCAACGAGGTGGAGTTAACATATGAA
>9.18|476105|40|NC_019693|PILER-CR
CACGTATTACTAAATGGATTAAAGATGCTTTCAATCCTGA
>9.19|476179|38|NC_019693|PILER-CR
CACGATGAGGATAAATTCATCAACCATTGCCACAGTGA
>9.20|476251|40|NC_019693|PILER-CR
CACCTGAACATCCGTTTCTAAGCGCTCCTCGTAAGAATGT
>9.21|476325|45|NC_019693|PILER-CR
CACTGCGATCGCCTGTGAGACTCCTGAACTTATCTCTAAGGTCGT
>9.22|476404|44|NC_019693|PILER-CR
AACAATGTTGAAATAGCCTATAGAAATGGTACTTGGTAGTATGG
>9.23|476482|41|NC_019693|PILER-CR
CACCCAGGAATAAGCTAATAAGTTTACTTTATGCGTTAAGA
>9.24|476557|43|NC_019693|PILER-CR
CACCTTGGGTGACCAACGGTTAAGGATAGCAGCAAGGGCTGTT
>9.25|476634|43|NC_019693|PILER-CR
CACTTCCATTAAGTAACCAATCACCTTATAAGGAGAATGATTA
>9.26|476711|48|NC_019693|PILER-CR
GACTAACCTGCTAGATGGATGGACCCTCATTTCCACGTCCAAGTAATT
>9.27|476793|39|NC_019693|PILER-CR
CACCTTACTTCTTAATTCAAGAATGTGACTTCTATCTAA

CRISPR arrays and Neighbor proteins around NC_019693_9

CRISPR arrays

The CRISPR arrays of NC_019693_9

>merge|NC_019693|9|475830-476937|CRISPRCasFinder,CRT,PILER-CR
TTTTCCGTCCCCTTGCGGGGAATTGATAGGAATTCACATAGTTATGGAATGGTTAGTCGAAGCGTTCTGTATGGCAATTTTGTTTCCGTCCCCTTGCGGGGAATTGATAGAAATTAACGCTCGGGAACGGGAAAATCTGGGTGGGGTAGTGCAAGTGACCCTGTTTCCGTCCCCTTGCGGGGAATTGATAGGAATTTACGTGGAATGGACGCCTTCAACGAGGTGGAGTTAACATATGAAGTTTCCGTCCCCTTCCGGGGAATTGATAGGAATTCACGTATTACTAAATGGATTAAAGATGCTTTCAATCCTGAGTTTCCGTCCCCTTACGGGGAATTGATAGGAATTCACGATGAGGATAAATTCATCAACCATTGCCACAGTGAGTTTCCGTCCCCTTGCGGGGAATGGATAGGAATTCACCTGAACATCCGTTTCTAAGCGCTCCTCGTAAGAATGTGTTTCCGTCCCCTTGCGGGGAATGGATAGGAATTCACTGCGATCGCCTGTGAGACTCCTGAACTTATCTCTAAGGTCGTGTTTCCGTCCCCTTGCGGGGAATTGATAGGAATTAACAATGTTGAAATAGCCTATAGAAATGGTACTTGGTAGTATGGGTTTCCGTCCCCTTGCGGGGAATTGATAGGAATTCACCCAGGAATAAGCTAATAAGTTTACTTTATGCGTTAAGAGTTTCCGCCCCCTTGCGGAGAATTGATAGGAATTCACCTTGGGTGACCAACGGTTAAGGATAGCAGCAAGGGCTGTTGTTTCCGTCCCCTTACGGGGAATTGATAGGAATTCACTTCCATTAAGTAACCAATCACCTTATAAGGAGAATGATTAGTTTCCGTCCCCTTGCGGGGAATTGATAGGGACTAACCTGCTAGATGGATGGACCCTCATTTCCACGTCCAAGTAATTGTTTCCGTCCCCTTGCGGGGAATTGATAGGAATTCACCTTACTTCTTAATTCAAGAATGTGACTTCTATCTAAGTTTCCGTCCCCTTGCGGGGAATTGATAGGAATTCACTAGGTATTGACCCTAACTTTCCTGATAAAGCCCTTATGACGTTTCCGTCCCCTTGCGGGGAATTGATAGAGATT

>NC_019693|9|9|475830-476937|CRISPRCasFinder
TTTTCCGTCCCCTTGCGGGGAATTGATAGGAATT	CACATAGTTATGGAATGGTTAGTCGAAGCGTTCTGTATGGCAATTTT
GTTTCCGTCCCCTTGCGGGGAATTGATAGAAATT	AACGCTCGGGAACGGGAAAATCTGGGTGGGGTAGTGCAAGTGACCCT
GTTTCCGTCCCCTTGCGGGGAATTGATAGGAATT	TACGTGGAATGGACGCCTTCAACGAGGTGGAGTTAACATATGAA
GTTTCCGTCCCCTTCCGGGGAATTGATAGGAATT	CACGTATTACTAAATGGATTAAAGATGCTTTCAATCCTGA
GTTTCCGTCCCCTTACGGGGAATTGATAGGAATT	CACGATGAGGATAAATTCATCAACCATTGCCACAGTGA
GTTTCCGTCCCCTTGCGGGGAATGGATAGGAATT	CACCTGAACATCCGTTTCTAAGCGCTCCTCGTAAGAATGT
GTTTCCGTCCCCTTGCGGGGAATGGATAGGAATT	CACTGCGATCGCCTGTGAGACTCCTGAACTTATCTCTAAGGTCGT
GTTTCCGTCCCCTTGCGGGGAATTGATAGGAATT	AACAATGTTGAAATAGCCTATAGAAATGGTACTTGGTAGTATGG
GTTTCCGTCCCCTTGCGGGGAATTGATAGGAATT	CACCCAGGAATAAGCTAATAAGTTTACTTTATGCGTTAAGA
GTTTCCGCCCCCTTGCGGAGAATTGATAGGAATT	CACCTTGGGTGACCAACGGTTAAGGATAGCAGCAAGGGCTGTT
GTTTCCGTCCCCTTACGGGGAATTGATAGGAATT	CACTTCCATTAAGTAACCAATCACCTTATAAGGAGAATGATTA
GTTTCCGTCCCCTTGCGGGGAATTGATAGGGACT	AACCTGCTAGATGGATGGACCCTCATTTCCACGTCCAAGTAATT
GTTTCCGTCCCCTTGCGGGGAATTGATAGGAATT	CACCTTACTTCTTAATTCAAGAATGTGACTTCTATCTAA
GTTTCCGTCCCCTTGCGGGGAATTGATAGGAATT	CACTAGGTATTGACCCTAACTTTCCTGATAAAGCCCTTATGAC
GTTTCCGTCCCCTTGCGGGGAATTGATAGAGATT

>NC_019693|9|1|475830-476937|CRT
TTTTCCGTCCCCTTGCGGGGAATTGATAGGAATT	CACATAGTTATGGAATGGTTAGTCGAAGCGTTCTGTATGGCAATTTT
GTTTCCGTCCCCTTGCGGGGAATTGATAGAAATT	AACGCTCGGGAACGGGAAAATCTGGGTGGGGTAGTGCAAGTGACCCT
GTTTCCGTCCCCTTGCGGGGAATTGATAGGAATT	TACGTGGAATGGACGCCTTCAACGAGGTGGAGTTAACATATGAA
GTTTCCGTCCCCTTCCGGGGAATTGATAGGAATT	CACGTATTACTAAATGGATTAAAGATGCTTTCAATCCTGA
GTTTCCGTCCCCTTACGGGGAATTGATAGGAATT	CACGATGAGGATAAATTCATCAACCATTGCCACAGTGA
GTTTCCGTCCCCTTGCGGGGAATGGATAGGAATT	CACCTGAACATCCGTTTCTAAGCGCTCCTCGTAAGAATGT
GTTTCCGTCCCCTTGCGGGGAATGGATAGGAATT	CACTGCGATCGCCTGTGAGACTCCTGAACTTATCTCTAAGGTCGT
GTTTCCGTCCCCTTGCGGGGAATTGATAGGAATT	AACAATGTTGAAATAGCCTATAGAAATGGTACTTGGTAGTATGG
GTTTCCGTCCCCTTGCGGGGAATTGATAGGAATT	CACCCAGGAATAAGCTAATAAGTTTACTTTATGCGTTAAGA
GTTTCCGCCCCCTTGCGGAGAATTGATAGGAATT	CACCTTGGGTGACCAACGGTTAAGGATAGCAGCAAGGGCTGTT
GTTTCCGTCCCCTTACGGGGAATTGATAGGAATT	CACTTCCATTAAGTAACCAATCACCTTATAAGGAGAATGATTA
GTTTCCGTCCCCTTGCGGGGAATTGATAGGGACT	AACCTGCTAGATGGATGGACCCTCATTTCCACGTCCAAGTAATT
GTTTCCGTCCCCTTGCGGGGAATTGATAGGAATT	CACCTTACTTCTTAATTCAAGAATGTGACTTCTATCTAA
GTTTCCGTCCCCTTGCGGGGAATTGATAGGAATT	CACTAGGTATTGACCCTAACTTTCCTGATAAAGCCCTTATGAC
GTTTCCGTCCCCTTGCGGGGAATTGATAGAGATT

>NC_019693|9|1|475831-476860|PILER-CR
TTTCCGTCCCCTTGCGGGGAATTGATAGGAATTC	ACATAGTTATGGAATGGTTAGTCGAAGCGTTCTGTATGGCAATTTTG
TTTCCGTCCCCTTGCGGGGAATTGATAGAAATTA	ACGCTCGGGAACGGGAAAATCTGGGTGGGGTAGTGCAAGTGACCCTG
TTTCCGTCCCCTTGCGGGGAATTGATAGGAATTT	ACGTGGAATGGACGCCTTCAACGAGGTGGAGTTAACATATGAAG
TTTCCGTCCCCTTCCGGGGAATTGATAGGAATTC	ACGTATTACTAAATGGATTAAAGATGCTTTCAATCCTGAG
TTTCCGTCCCCTTACGGGGAATTGATAGGAATTC	ACGATGAGGATAAATTCATCAACCATTGCCACAGTGAG
TTTCCGTCCCCTTGCGGGGAATGGATAGGAATTC	ACCTGAACATCCGTTTCTAAGCGCTCCTCGTAAGAATGTG
TTTCCGTCCCCTTGCGGGGAATGGATAGGAATTC	ACTGCGATCGCCTGTGAGACTCCTGAACTTATCTCTAAGGTCGTG
TTTCCGTCCCCTTGCGGGGAATTGATAGGAATTA	ACAATGTTGAAATAGCCTATAGAAATGGTACTTGGTAGTATGGG
TTTCCGTCCCCTTGCGGGGAATTGATAGGAATTC	ACCCAGGAATAAGCTAATAAGTTTACTTTATGCGTTAAGAG
TTTCCGCCCCCTTGCGGAGAATTGATAGGAATTC	ACCTTGGGTGACCAACGGTTAAGGATAGCAGCAAGGGCTGTTG
TTTCCGTCCCCTTACGGGGAATTGATAGGAATTC	ACTTCCATTAAGTAACCAATCACCTTATAAGGAGAATGATTAG
TTTCCGTCCCCTTGCGGGGAATTGATAGGGACTA	ACCTGCTAGATGGATGGACCCTCATTTCCACGTCCAAGTAATTGTTTC
CGTCCCCTTGCGGGGAATTGATAGGAATTCACCT	TACTTCTTAATTCAAGAATGTGACTTCTATCTAAGTTTC
CGTCCCCTTGCGGGGAATTGATAGGAATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_156824014.1|461552_465572_-|amino-acid-adenylation-domain-containing-protein	unknown	unknown	gnl|CDD|237108
NC_019693.1|WP_015146794.1|480626_481118_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146787.1|472052_475379_-|non-ribosomal-peptide-synthetase	unknown	unknown	gnl|CDD|237108
NC_019693.1|WP_015146797.1|481923_483165_-|TIGR02221-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	gnl|CDD|378186
NC_019693.1|WP_015146788.1|477271_477487_-|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|273699
NC_019693.1|WP_015146777.1|456942_457812_-|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_019693.1|WP_015146795.1|481114_481339_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146789.1|477740_478658_+|DUF4351-domain-containing-protein	unknown	unknown	gnl|CDD|316753
NC_019693.1|WP_015146786.1|467334_472056_-|non-ribosomal-peptide-synthetase	unknown	unknown	gnl|CDD|237108
NC_019693.1|WP_015146778.1|457879_459520_-|BamA/TamA-family-outer-membrane-protein	unknown	unknown	gnl|CDD|130065
NC_019693.1|WP_015146790.1|478775_479180_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350312
NC_019693.1|WP_015146784.1|465653_466256_-|hypothetical-protein	unknown	unknown	gnl|CDD|376158
NC_019693.1|WP_015146796.1|481494_481656_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044194296.1|480117_480591_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146792.1|479559_479844_+|DUF4351-domain-containing-protein	unknown	unknown	gnl|CDD|316753
NC_019693.1|WP_015146785.1|466266_467301_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|349760
NC_019693.1|WP_015146781.1|460472_460652_-|30S-ribosomal-protein-S21	unknown	unknown	gnl|CDD|234707
NC_019693.1|WP_015146791.1|479176_479422_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146779.1|459595_460180_-|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_019693.1|WP_015146782.1|460902_461232_-|RNA-binding-protein	unknown	unknown	gnl|CDD|240845

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_015146788.1|477271_477487_-|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	4e-12	41.1	0.0
NC_019693.1|WP_015146797.1|481923_483165_-|TIGR02221-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	2.7e-76	251.8	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_156824014.1|461552_465572_-|amino-acid-adenylation-domain-containing-protein	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NC_019693.1|WP_015146787.1|472052_475379_-|non-ribosomal-peptide-synthetase	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NC_019693.1|WP_015146788.1|477271_477487_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|273699	TIGR01573, cas2, CRISPR-associated endonuclease Cas2. This model describes most members of the family of Cas2, one of the first four protein families found to mark prokaryotic genomes that contain multiple CRISPR elements. CRISPR systems protect against invasive nucleic acid sequences, including phage. Cas2 proteins have been characterized as either endoribonuclease (for ssRNA) or endodeoxyribonuclease (for dsDNA), depending on the system to which the Cas2 belongs. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats. The cas genes usually are found near the repeats. A distinct branch of the Cas2 family shows a very low level of sequence identity and is modeled by TIGR01873 instead of by this model (TIGR01573).	1.29477e-13
NC_019693.1|WP_015146777.1|456942_457812_-|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.52629e-29
NC_019693.1|WP_015146789.1|477740_478658_+|DUF4351-domain-containing-protein	gnl|CDD|316753	pfam14261, DUF4351, Domain of unknown function (DUF4351). This domain is found in bacteria, and is approximately 60 amino acids in length.	5.94416e-21
NC_019693.1|WP_015146786.1|467334_472056_-|non-ribosomal-peptide-synthetase	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NC_019693.1|WP_015146778.1|457879_459520_-|BamA/TamA-family-outer-membrane-protein	gnl|CDD|130065	TIGR00992, chloroplast_import-associated_channel_homolog, chloroplast envelope protein translocase, IAP75 family. Two families of proteins are involved in the chloroplast envelope import appartus.They are the three proteins of the outer membrane (TOC) and four proteins in the inner membrane (TIC). This family is specific for the TOC IAP75 protein. [Transport and binding proteins, Amino acids, peptides and amines].	3.66224e-58
NC_019693.1|WP_015146790.1|478775_479180_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350312	cd18745, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily. The PIN_VapC4-5_FitB-like subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This subfamily belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.61838e-54
NC_019693.1|WP_015146784.1|465653_466256_-|hypothetical-protein	gnl|CDD|376158	pfam18735, HEPN_RiboL-PSP, RiboL-PSP-HEPN. RiboL-PSP-HEPN. Fused to endoRNase L-PSP ; in operon with ParB.	9.64525e-08
NC_019693.1|WP_015146797.1|481923_483165_-|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	1.30474e-78
NC_019693.1|WP_015146792.1|479559_479844_+|DUF4351-domain-containing-protein	gnl|CDD|316753	pfam14261, DUF4351, Domain of unknown function (DUF4351). This domain is found in bacteria, and is approximately 60 amino acids in length.	2.15978e-19
NC_019693.1|WP_015146785.1|466266_467301_-|AAA-family-ATPase	gnl|CDD|349760	cd02042, ParAB_family, partition proteins ParAB family. ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single-stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis. ParA shares sequence similarity to a conserved and widespread family of ATPases which includes the repA protein of the repABC operon in Rhizobium etli symbiotic plasmid. This operon is involved in the plasmid replication and partition.	2.95678e-08
NC_019693.1|WP_015146781.1|460472_460652_-|30S-ribosomal-protein-S21	gnl|CDD|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	1.25788e-13
NC_019693.1|WP_015146779.1|459595_460180_-|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	7.14305e-27
NC_019693.1|WP_015146782.1|460902_461232_-|RNA-binding-protein	gnl|CDD|240845	cd12399, RRM_HP0827_like, RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins. This subfamily corresponds to the RRM of H. pylori HP0827, a putative ssDNA-binding protein 12rnp2 precursor, containing one RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain). The ssDNA binding may be important in activation of HP0827. .	4.93334e-33

Protein sequences

>NC_019693.1|WP_015146787.1|472052_475379_-|non-ribosomal-peptide-synthetase
MESNIFNSPLTPAPDALNLSPETDVFVFPTSFAQQRLWFIDQFAPGHSFYNVTTALRLTGVVNFPALADTFIEIGRRHETLRTRFTTVEGEPVQVISPEADIPVNWVDLRQFSPGEREAEASRLAAVEAEFPFNLATGPLLRVTLLQLEDSLSILLLNMHHIISDDWSMGVFVQELGTIYRALVENRPVLLPELPLQYADFAEWQREWFQGEVLEEQLGYWRQQLRGIVSLNLPGDSPKQATPSYQGKSQVFELSQPLTAALKALSQQEGVTLFMTLLAGFQTLLYRYSQQDEITVGSPIANRNRSEIEGLIGFFVNSLVLRTDVSGNPTFRELLARVREVTLGAYAHQDLPFEKVVEALHPDRVLNVHPLFQVVFNLQNAPMQELDLPGLTVSSMSLGVKTTRFDLEVHLWESADSFRSVYGQDWQHQDSLRGFVIYNTDKFESGTVAQMLEQFKNLLKNIVKNPNQGVEELELISDGERDRILIEWNQTQAEYPAETAIQALFEAQVQANPQAVAVTIAGESLTYQELNQRSNQWAHYLQHLGVGDEEIVGLCAAKSLDTIVGMLGILKAGGAYLPLDPTYPGDRLNWMMADAGVRLLLVPDELRGKFKGFEGVMVGGDCDGEAVTREPVENLPHFPGGSRLAYVIYTSGSTGTPKGVAVPHQAVNRLVLNTNYIQITPKDTLAQVSNLSFDAATFEIWGALLNGAHLKGISTEITLSPHDFARELRQQQIDILFLTTALFQQVVRTVPQAFQSLRCLLFGGETVDPRWVKKVLHQGMPQQLIHVYGPTENTTFSTYFSIEAMAEPASSVPIGKAVANTELYLLDPHLQPVAVGVPGELYLGGEGLARGYLNRPDLTEERFISNPFGKPGTRLYKTGDLARYKSDGNLEFLGRIDHQVKIRGFRIELGEIEAVLCQYSGVAAAVAIAREEIPGEKELVAYVVPRDPEGKSSPLKISELRRFLSEKLPSYMLPTAYAILEVLPLTQNGKINRQILPEIETAFQELSQNYVNPRTEVEEVLVDIWREVLGKQQVSVYDNFFELGGHSLLATQLISRIRDGLKIELPVSQLFEAPTVASLANYIETVCWAAQPQKLPKSYQNDREEVEF
>NC_019693.1|WP_015146786.1|467334_472056_-|non-ribosomal-peptide-synthetase
MNTLEFLSELRELEIHLNVEGSRLICQAPEGRLTPQLREQISQRKGDILAFFQRANRSMNETPVGLKPISRTGNLPLSFAQQRLWFLDRLVPNNPFYNMPAAVRLTGEVNLELLEAAFNEIIRRHEALRTVFPEGEGQGIQEIQAHQTVPIHVLNLQNLSAAEQEKQVERIITHEALRPFNLSTGPLLRISLLQLGETDYLLMLNMHHIISDGWSIGVLIQELGILYGAFFQGESSPLPELGIQYADFAHWQREWLQGEILEHQLAYWRQQLEGISMLNLPSDRPRPAVPSYRGKRYGFRLSQEVSQKLDALTQGEGVTLFMTLLAAFQTLLYRYSQQEDITVGSPIANRNRSEIEPLIGFFVNSLVLRTDLSGNPTFREVLARVKQVALGAYAHQDVPFEKLVEELHPERSLNHNPLFQVAFALQNAPMQGLELPGLTLSPQPLEAGTARFDLELHLWEQSSTNPMWVDSREGISGFVIYSTDLFEESTIGRLVAHFQTLLEAIVANPDQQIGDLPILSEAERHQLLVQWNQTEVDYPQELAVHQLVEIQAAEHPEKVALVCGNKTLTYGELNRRSNQLAHYLQKLGVGTEVAVGLCLDRTLEMAVAMLGILKAGGAYLPLDPSVPSSRLNRMLTEAKVPVLLTQQSSLSQFNRVICKIVCLDTDKALIERQPDENLSSSVTPNSLAYVIYTSGSTGEPKGVEIEQKSLLNLTYWHQQAFAVSASDRSTQVAGVAFDACGWEIWPYLTAGACIYIVDNETRRSPEKLRDWLVENAITISFLPTPLAEQVLQLKWPEQTPLRLLLTGGETLHQHPLPSHPFEVVNNYGPTENTVVTTSGRVPVGNGREIAPGIGKAVANTQLYVCDRYFHPVPIGIPGELYIGGDGLARGYRHHPELTAEAFIRNPLQPEPGNFLYKTGDLVRYQPDGSLEFLGRLDQQVKIRGFRIELGEIEVILSQHPAVNQTLVTVSESDRGETQLTAYLALNLQRVELAETNPVALQEEQVQQWQILYNETYKMPAVGMEPHFNIVGWNSSYTNEPIPAAEMREWVDHQAAKILALEPKNVLEIGCGTGLLLFRIAPHCTDYCGTDFSPPSLNFIRKHLGKYDLEQVTLLEKLATNFDGIPPQSFDTVILNSIVQYFPSLDYLTQVISGAVAATKPGGRIFLGDLRSLPLLKAFYTDVELTRAQPCVTRQQLQQRVEMQLFQEVELALDPAFFTSLKSHLPQIETVEIQLMRGQSRNELTQFRYNAILHLAGSEVKSKSAKNHPITWLNQGETRDDWTVEKLRQYLIETNPDICGLSQVPNSRVMAAVQATEWLFNSRPFKTAGQLKKAVQNLHNSGINPEDWYGLELPYRVHIRWSDSMGEGRYDVVFVREDIPEFILEASDAPPLAFAYANNPLKGKAARQFVPELRAYLNEKLPDYMIPSAFVVLEYLPLTANGKIDRHALPTATAIAPELAGNYAPPRTVIEEHLAQIWAEVLGIKRVGIYDNFFELGGHSLLATQLASRVRDKFGFELPLRSVFEAPTIAQLAPIVAGLKQQNPTHHAPALVPVSRDRRRMKLSSLNPQPPQKL
>NC_019693.1|WP_015146785.1|466266_467301_-|AAA-family-ATPase
MSSYAFWNNKGGVGKSFLSFVAASEYAHSHPDTDVYVIDLCPQAKVSEILFGGYQSSPKAIHSLSEKKPRATIAGYLEARLNSPFRMIEDVSPYLCTPKAFNSHIPENLKLICGDNLLEIISEAIRQTSELSIPADAWKQVLNWVQDLTVALRKQSGDRDTLFVIDCNPSFAIYTQIGLVAAEGVVVPFTADDSSRRVLENVIALLYGITDPQSEPYARISFGKRAKEEGVSVPKLHTFVSNQVAVNQGQPSRDFEAVNQTIKQMMDELHKKHRHIFATPKEQPSNTFMLIPDYQSAYVVATTTGTPLYKLKPGPQNLVNEHIELDSEPLQNYRNALETFVNCL
>NC_019693.1|WP_015146784.1|465653_466256_-|hypothetical-protein
MPSPAALKYQSASNTARILRQTASDPRLQPISRNQTQVYYHSALAAFVAAWDAYINELVRNFFAVTANPLDPKFHAVHSIARETASRALERFNTPNADNTRNLLIQYTGYDPIGDWVWSAKNMSGVAVRQKLNEILRVRHSFAHGFSIPAFSWTQTATGKVRLTAKGIDEVDGFFKYLVKVTDQGMKQHIETNYSLVLPW
>NC_019693.1|WP_156824014.1|461552_465572_-|amino-acid-adenylation-domain-containing-protein
MTQETEVFVFPASFAQQRLWFLNQLAPDNPFYNVSAAIQLTGNLNLSALEESVNEIVRRHETLRTTFALLEGQVVQVIAPELTLAVQAIALQHLPPSEQHSEAQRLATLAAAEPFDLTTGPLLRVSVLQQSETDSILLLNFHHIVADGWSIGILLGELGTLYTAFAHQQPSPLPDLPLQYADFTEWQQQWLQGEFLETQLTYWQQQLQHLSPLNLPSSRPRPPIPSYRGGQQQFALSPALTASIKQLSQQTETTLFMTLLAAFKTLLYRYTGQTDIAVGSPIANRNRQEIEGLIGFFVNSLVLRTNLSGNPTFLELLTQVKSVAVAAYAHQDLPFEKLVEELHPQRDLSQNPLFQVSFSLQNTPTNALELPGITLSLLEWDIPRAKLDLEVNFWEESDQIKGQVIYSTDLFDCSTITRWMGHFQTLLSEIVTDPNQQISDLPILTPEEQDCLLFEFNSPAYPFLPQPRLQHPSFLHLFEEIVQRSPHQIALISGKNSLTYHDLHHQSNQIARYLQQWGVKPEKLVGLCLPPSIEAVACILGILKAGGVYLYCDPTYPPERLQFILSDAEVSLLLTRSPFVPSQTPPQVSILDLAQHQGAIAQQSPESLTYPITPNHLAYVIYTSGSTGKPKGVLIEHRGISNLILAQHQIFKLNQNSRILQFASLSFDASIFEIVMAFSTGATLYLADEESRYGGSVLMTFLSDSAITHATLPPAVLATLPYGKLPALHTLISAGESCSPALAKPWVNSCHFFNAYGPTESTVWATVAEITEPSQNLPIGRPISNTQVYLLDANLQPVPIGIPGEIYIAGEGLARGYLNRQQLNSERFITHAFTPVKTVRLYKTGDLARYQADGNLEFLGRLDHQVKIRGYRIELGEIEVIIAQYYNIKQARVIATDQGQLVAYIVPIANQPINRSELQSFLGKTLPRYMIPQEVIVLDSLPLTDRGKLDRNRLPSPKTLTSRQFIPPGNPSEAALAQIWATLLKCDRVSMKDNFFDLGGDSLLAVRLLTQINQQFQQQLPVSALFLNPTLQGLANCLFSELDTLPCSPLVPIQTQGTNPPFFCIHPILGVVFPYYELALNLGKNQPFYALQPQGIDGKFPPLTRIEEMAAYYIKAMRTIQPDGPYFLGGWSFGGLVAFEMAQQLKKAGHPVGLLAVLDTLAPVSTNQPSLWQGGKFLFTTAASSIWPFLRDYVYLMTQGKQRQKEVFNPRGDRLPQRVHPLFNFLHRYLAKTTLAQSLHSTSDRRLLREVTLRPLLPIFQANSQAVLQYQPSIYPDHITLIASSDRAIATGEDPTLGWGQLTEEPIKLIRIPGNHLTMLRKPQVQYLADHLRECLESQ
>NC_019693.1|WP_015146782.1|460902_461232_-|RNA-binding-protein
MSIYVGNLSYDVTEQDLNSVFAEYGTVKRVNLPTDRETGRPRGFGFVEMDTDAEETAAIEALDGAEWMGRDLKVNKAKPREDNKRGGGGGGGNRGGRGGYGGGGGGGYR
>NC_019693.1|WP_015146781.1|460472_460652_-|30S-ribosomal-protein-S21
MTQVLVGESEGIESALRRFKRQVSRAGILADVKCRRHFETPQEKRKRKASAARRKRRYR
>NC_019693.1|WP_015146779.1|459595_460180_-|pentapeptide-repeat-containing-protein
MDTDELLNRYREGERDFPGVDLRGCYLYRAHLPEINLAGANLTHANLGRANLNGANLSGANLTDAKLTATLLKKANLSDAVLTRANLMLAQLGQADLNRVDLQGASLWKASLNKADLMNANLSNTDCSGADLVSTSFVGANLQESDLSSANLIAADFGGANLTDAKLIGANLWNSNLYGANLHNTILPDGHHHL
>NC_019693.1|WP_015146778.1|457879_459520_-|BamA/TamA-family-outer-membrane-protein
MRSPVPQMPKIEKIWGAIEVQNREVFLPPTPIIALSSSVARSPERATDTITESVGVNGMTANIILYKSLEALALLLGATSALFITRLPAWGQRAETTPFNLQSLYPPAADGLLPATPSLDTPPPPPLLGDHQSPSPLRGGVWGEVSSTDAPPQSSYSAENLQGEGLERGISQQRQNPPTQPQRPELETIQEELDEDPDFAIVPLPRYSAIKGIHGTVDFILTNLGENNQTLDLRLEGGERTIGAIFRYTDPWLESGPFDSGYQLRLFNTRSPESQFLEGDREVNLIHDHEAWVDRLGGSLSFYQPVTATGVVLSAGASYQRVAIRNSAFTDRLYASDRLGNPLTFSEQGLDTLITVNLGVLQDRRNSTEWPTQGYRFQLATEQSIPVGSADILFNRLSASFTQFVPVQNQTFVFNLQGGTILGDVPPYQAFNLGGSDSVRGYQDGEIGTGQSYIQGTVEYRFPLIEDLDIPYSSALSGTVFADFASDLGSADSVYGEPGEVRNKPGNGFGVGLGVRLLTDFGPVRLEFAVSDQRDLSAIFKIGERF
>NC_019693.1|WP_015146777.1|456942_457812_-|pentapeptide-repeat-containing-protein
MDIHQLLTRYAQGERLFSKVNLCEAHLSGTNLSRAVFRDATLQEINLSSAYLRRTDFRGADLKGADLRGAYLKGADLRGTDLRWADMGGTDISDALYNSQTQFPIGFDAKGRNAYAIAPNADLSRAYLYKADLRWTQITDANLAHAYLYRADLRSADLRGADLSEADLRSALCDADTCFDEGFDTNRAGVYAIGPQSSLVDATLSGARLSGVDLSGSDLSGADLTRADLSRANLENTNLTGANLTGANLLGANLLGAKITDAEFAEADLRGAIAPDGSTALIDLQKSAS
>NC_019693.1|WP_015146788.1|477271_477487_-|CRISPR-associated-endonuclease-Cas2
MEQRCQRVQYSVFECPLDEETLTGLMENPWVKVLNLSEDSLRAYPLTWTAKKLAKIYGSPPMYEPPDYLIF
>NC_019693.1|WP_015146789.1|477740_478658_+|DUF4351-domain-containing-protein
MIDHDRLFKELLETFLPEFLELFFPQLWNALDPDSLSFQDKELFTDITSGEKYAADLVIRAQLKYGKIPILIHLEHQARSEPNFPRRMFIYFCRLLEKYAISIYPIAVLSFDTPQRADPNTYQVECCGKVVNRFNYEVIQLNRLNWQDFRDSNNAIGCALMAKMQMERGERPQVKLECLRMLHHLNLNPARTQLISGFIDIYLRLNPEEQALFQAQLSTILPQEQEGVMEIVTSWMEQGIEQGRRQAAVSLVQRQLNRRCGGISPELDLAVQQLSTPQLEELSEALLDFTSEADLVAWLNERTEG
>NC_019693.1|WP_015146790.1|478775_479180_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MIYLLDTNTCIQYLTGRSENVSYKFKTTPRQNIGLCDVVKAELYYGACRSAKKEQNLALYELFFSQYISLPFEGKSAKVYGEIRAELSRLGIPIGPYDFQIAAIALANNLILVTHNTQEFKRIQNLKLEDWEIL
>NC_019693.1|WP_015146791.1|479176_479422_-|hypothetical-protein
MKLTLKSKVDAEGKLFLQLPPEFANQELDIIIDSAQEPMPTPEDLGYPADFFEKTAGKWQGEPWVREDLGDCDRRIWDVEP
>NC_019693.1|WP_015146792.1|479559_479844_+|DUF4351-domain-containing-protein
MSSLYFQAELSTILPQQQEGVMEIVTSWMEQGMRQATVSLVQRLLNRRCGGISPELDLAVQQLSTPQLEELSEALLDFTSEADLVAWLNERTEG
>NC_019693.1|WP_044194296.1|480117_480591_-|hypothetical-protein
MTRTPHQAQESETRARKNYTAVDFFMASEQSHREQAELNQQAAQDLRDTKPDWAVTMCFYSALHWVEFYAKTHGCDNLGQQYPGRSLHESRTQYVDDLARDLGNRALRKAYEELERTSKKSRYLQNINTNSREFFNKQKKEVNKSFENLRIITQLLS
>NC_019693.1|WP_015146794.1|480626_481118_-|hypothetical-protein
MIMPSIPRNTLEPISTKNSWNNVYYSPVLIPRTGESKPSPAVSSASELVQTLSKIKGVKRVRAIAPRPTDLHWLQFDLALQPDSELSDESWEKIQNLIIDAEWSLRDSTQEKWYFHAEVVENYETIREGAKVIVNSDKKSFDSSITHLTNRSDFIPRLKVLTP
>NC_019693.1|WP_015146795.1|481114_481339_-|hypothetical-protein
MNELDRNRVHFITGITIAMDHEDGVLILGMLSDSPFSDNQAEAQTKEPISNFALTRQKAKFLREKLDEFLRESE
>NC_019693.1|WP_015146796.1|481494_481656_-|hypothetical-protein
MANPKTSDALNQNDYYSALTRSEFFPKPAKVSVCESTYSIHSLQITHYQRVIR
>NC_019693.1|WP_015146797.1|481923_483165_-|TIGR02221-family-CRISPR-associated-protein
MQLLTFLGTGNYSKTCYNWESQEKETAYVAEALAEFFQATSVRAFVTSEAMEMHGEQLKSCLTEVDFEFVPIPSGKSEAEIWEIFEAVVTAVEPGSEVIFDITLALRSIPLLVLLASAFLQKARNVQIKGVYYGAFEVNRDRPPIFDITPAIKLLDWLTATDKFVSTGSSLELGKLLSTIQQDFYTNRSPQSSKTIKPTRLKSLGTTIQNISRSLELVRPMGLMEEAAKLQAIPVEDLQTELGEFAKPFELLLSQIQEDYGQFALANSRQGDPKTVLKQQFLLLQWYGKKGLGTQGILLAREWIISALCIAQKIDYLDRNKRGLIERQLSLISDWQREKGSDESVVDYAPASISKTVEKVEDLAKFWSQLTEVRNDLAHTEMRVHSLGASKLDAYVKDELIQGISALFPEWIE

Crispr_ID: NC_019693_10

• CRISPR_ID: NC_019693_10
• CRISPR_location: 523242-523357
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_10

Consensus_repeat	Method
TAGGAGAGGGCCGGGGAGAGGTCTCTTG	CRISPRCasFinder

spacers of NC_019693_10

>10.1|523270|60|NC_019693|CRISPRCasFinder
ATTCTCCCTCTCCTCTTAGGAGAGGGCCGGGGAGAGGTCTCTTGATTCTCCCTCTCCTCT

CRISPR arrays and Neighbor proteins around NC_019693_10

CRISPR arrays

The CRISPR arrays of NC_019693_10

>merge|NC_019693|10|523242-523357|CRISPRCasFinder
TAGGAGAGGGTCGGGGAGAGGTCTCTTGATTCTCCCTCTCCTCTTAGGAGAGGGCCGGGGAGAGGTCTCTTGATTCTCCCTCTCCTCTTAGGAGAGGGCCGGGGAGAGGTCTCTTG

>NC_019693|10|10|523242-523357|CRISPRCasFinder
TAGGAGAGGGTCGGGGAGAGGTCTCTTG	ATTCTCCCTCTCCTCTTAGGAGAGGGCCGGGGAGAGGTCTCTTGATTCTCCCTCTCCTCT
TAGGAGAGGGCCGGGGAGAGGTCTCTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015146848.1|528823_529585_+|hypothetical-protein	unknown	unknown	gnl|CDD|370129
NC_019693.1|WP_015146841.1|522023_522608_-|PAP-fibrillin	unknown	unknown	gnl|CDD|309752
NC_019693.1|WP_015146851.1|532216_533119_+|DUF928-domain-containing-protein	unknown	unknown	gnl|CDD|368720
NC_019693.1|WP_156823707.1|518367_521058_+|phospholipid-carrier-dependent-glycosyltransferase	unknown	unknown	gnl|CDD|224720
NC_019693.1|WP_156824015.1|527615_528548_+|M48-family-peptidase	unknown	unknown	gnl|CDD|370932
NC_019693.1|WP_015146852.1|533402_535382_+|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl|CDD|226703
NC_019693.1|WP_015146845.1|525756_526521_-|HAD-family-hydrolase	unknown	unknown	gnl|CDD|319830
NC_019693.1|WP_015146834.1|514704_515007_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044196303.1|523522_524617_+|phospho-N-acetylmuramoyl-pentapeptide--transferase	unknown	unknown	gnl|CDD|234638
NC_019693.1|WP_015146844.1|524716_525688_+|glycosyltransferase	unknown	unknown	gnl|CDD|274884
NC_019693.1|WP_015146850.1|530572_531892_-|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl|CDD|366370
NC_019693.1|WP_015146849.1|529691_530333_-|SH3-domain-containing-protein	unknown	unknown	gnl|CDD|377965
NC_019693.1|WP_015146837.1|516601_517264_-|hypothetical-protein	unknown	unknown	gnl|CDD|237177
NC_019693.1|WP_015146846.1|526713_526974_-|DUF1830-domain-containing-protein	unknown	unknown	gnl|CDD|370162
NC_019693.1|WP_156823706.1|515343_515664_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044196302.1|517685_518135_-|hypothetical-protein	unknown	unknown	gnl|CDD|367843
NC_019693.1|WP_044194314.1|521172_522024_-|PD-(D/E)XK-nuclease-superfamily-protein	unknown	unknown	gnl|CDD|378929
NC_019693.1|WP_083896729.1|515756_516512_+|site-specific-integrase	unknown	unknown	gnl|CDD|271189
NC_019693.1|WP_015146842.1|522858_523092_+|DUF3134-domain-containing-protein	unknown	unknown	gnl|CDD|371474
NC_019693.1|WP_015146836.1|515126_515336_+|MYND-finger	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015146848.1|528823_529585_+|hypothetical-protein	gnl|CDD|370129	pfam08797, HIRAN, HIRAN domain. The HIRAN domain (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p. The HIRAN domain is found as a standalone protein in several bacteria and prophages, or fused to other catalytic domains, such as a nuclease of the restriction endonuclease fold and TDP1-like DNA phosphoesterases, in the eukaryotes. It has been predicted that this domain functions as a DNA-binding domain that probably recognizes features associated with damaged DNA or stalled replication forks.	3.14116e-08
NC_019693.1|WP_015146841.1|522023_522608_-|PAP-fibrillin	gnl|CDD|309752	pfam04755, PAP_fibrillin, PAP_fibrillin. This family identifies a conserved region found in a number of plastid lipid-associated proteins (PAPs), and in a number of putative fibrillin proteins.	1.48743e-63
NC_019693.1|WP_015146851.1|532216_533119_+|DUF928-domain-containing-protein	gnl|CDD|368720	pfam06051, DUF928, Domain of Unknown Function (DUF928). Family of uncharacterized bacterial protein.	1.80723e-67
NC_019693.1|WP_156823707.1|518367_521058_+|phospholipid-carrier-dependent-glycosyltransferase	gnl|CDD|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	1.10107e-24
NC_019693.1|WP_156824015.1|527615_528548_+|M48-family-peptidase	gnl|CDD|370932	pfam10263, SprT-like, SprT-like family. This family represents a domain found in eukaryotes and prokaryotes. The domain contains a characteristic motif of the zinc metallopeptidases. This family includes the bacterial SprT protein.	0.000903959
NC_019693.1|WP_083896729.1|515756_516512_+|site-specific-integrase	gnl|CDD|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.75232e-31
NC_019693.1|WP_015146852.1|533402_535382_+|adenylate/guanylate-cyclase-domain-containing-protein	gnl|CDD|226703	COG4252, COG4252, Predicted transmembrane sensor domain [Signal transduction mechanisms].	1.74575e-130
NC_019693.1|WP_044196303.1|523522_524617_+|phospho-N-acetylmuramoyl-pentapeptide--transferase	gnl|CDD|234638	PRK00108, mraY, phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional.	1.35754e-128
NC_019693.1|WP_015146850.1|530572_531892_-|mechanosensitive-ion-channel-family-protein	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	8.01601e-53
NC_019693.1|WP_015146849.1|529691_530333_-|SH3-domain-containing-protein	gnl|CDD|377965	pfam08239, SH3_3, Bacterial SH3 domain.	6.24877e-05
NC_019693.1|WP_015146837.1|516601_517264_-|hypothetical-protein	gnl|CDD|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	0.000345451
NC_019693.1|WP_044196302.1|517685_518135_-|hypothetical-protein	gnl|CDD|367843	pfam04151, PPC, Bacterial pre-peptidase C-terminal domain. This domain is normally found at the C-terminus of secreted bacterial peptidases. They are not present in the active peptidase. It is possible that they fulfill a similar role to the PKD (pfam00801) domain, which also are found in this context. Visual analysis suggests that PKD and PPC are distantly related (personal obs:Bateman A, Yeats C).	4.68587e-05
NC_019693.1|WP_015146846.1|526713_526974_-|DUF1830-domain-containing-protein	gnl|CDD|370162	pfam08865, DUF1830, Domain of unknown function (DUF1830). This family of short proteins is functionally uncharacterized.	2.4052e-38
NC_019693.1|WP_044194314.1|521172_522024_-|PD-(D/E)XK-nuclease-superfamily-protein	gnl|CDD|378929	pfam12705, PDDEXK_1, PD-(D/E)XK nuclease superfamily. Members of this family belong to the PD-(D/E)XK nuclease superfamily.	4.70328e-26
NC_019693.1|WP_015146845.1|525756_526521_-|HAD-family-hydrolase	gnl|CDD|319830	cd07528, HAD_CbbY-like, subfamily of beta-phosphoglucomutase-like family, similar to Rhodobacter sphaeroides xylulose-1,5-bisphosphate phosphatase CbbY. This family includes Rhodobacter sphaeroides and Arabidopsis thaliana xylulose-1,5-bisphosphate phosphatase CbbY which convert xylulose-1,5-bisphosphate (a potent inhibitor of Ribulose-1,5-bisphosphate carboxylase/oxygenase, Rubisco), to the non-inhibitory compound xylulose-5-phosphate. It belongs to the beta-phosphoglucomutase-like family whose other members include Lactococcus lactis beta-PGM, a mutase which catalyzes the interconversion of beta-D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), Saccharomyces cerevisiae phosphatases GPP1 and GPP2 that dephosphorylate DL-glycerol-3-phosphate and DOG1 and DOG2 that dephosphorylate 2-deoxyglucose-6-phosphate, and Escherichia coli 6-phosphogluconate phosphatase YieH. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.99258e-86
NC_019693.1|WP_015146842.1|522858_523092_+|DUF3134-domain-containing-protein	gnl|CDD|371474	pfam11332, DUF3134, Protein of unknown function (DUF3134). This family of proteins with unknown function appears to be restricted to Cyanobacteria.	9.42957e-23
NC_019693.1|WP_015146844.1|524716_525688_+|glycosyltransferase	gnl|CDD|274884	TIGR03965, glycosyltransferase_Rv0696_family, mycofactocin system glycosyltransferase. Members of this protein family are putative glycosyltransferases, members of pfam00535 (glycosyl transferase family 2). Members appear mostly in the Actinobacteria, where they appear to be part of a system for converting a precursor peptide (TIGR03969) into a novel redox carrier designated mycofactocin. A radical SAM enzyme, TIGR03962, is a proposed to be a key maturase for mycofactocin.	1.70832e-48

Protein sequences

>NC_019693.1|WP_015146842.1|522858_523092_+|DUF3134-domain-containing-protein
MYNPSLREESRYKIADVIPLQQETSILDWLESNGRLIAREEKESEYAIDEEEIAALMSVEDNTYDDDDDDNELVEED
>NC_019693.1|WP_015146841.1|522023_522608_-|PAP-fibrillin
MIGKTELLEAIAGKNRGILATPSQKQAILAAVSQLEDRNPTPRPVEATDLLGGNWRLLYTTSDELLRLDRFPLASLGQIYQCVRPSQGKIYNIAEISGLPSLDVLVSVAARFEVVSERRVDVKFERAVAGLQRLIGYQSPNAFIDQIETGKKFLALDFQIPSGEQQGWLDITYLDCDLRIGRGNKDSVFVLTKS
>NC_019693.1|WP_044194314.1|521172_522024_-|PD-(D/E)XK-nuclease-superfamily-protein
MNPQATREDFPVHSQNRLSQGQLNMLQTCPRKFQYTYLEHLSSPVTPDQREKMAWGSQFHLLMQQRELGLPVEVLLQADEQMQRCYQGLLEAAPNLFEPESLGKQQFRAAEHRRIMNFQGYLFTVIYDLIIADEFSAQILDWKTYPLPKKDRTLEENWQTRLYPFVLAETSDYAPEDITMTYWFVQSAETGDDRQSKCESWTFYYNRLKHQETAQSLTHLLNQLNSWTADYESRKPFPQVAVTEGICYTCPFLTRCQRGGDSGFRLDQGDRSPAFSDIEEVAL
>NC_019693.1|WP_156823707.1|518367_521058_+|phospholipid-carrier-dependent-glycosyltransferase
MGRVKNYQKHHGWLTIAGLWLLGALGDRLWFALDHSIPSWDQADYLTGALNYWQALQSPQWFSGEWWRSLWLLSSKMPPGTYIVTAFFHNLFGIEADRATLVYLFFSAILLPSVYGLGRVLFNPKIGVWAAALCLMFPGLYHARLDFILDFPLTTLVTFSFYSLTLWKVTESLEFAPVPSENLPQHDVSFFLKSPTCQSWFWAIVLGLSVGLSLMIKQTALFFLITPIVWVIVSTIRGRRWVRFLQLMMAAFLTGLVMYPWYGTNWLLVFTGSQRAAIQAAVAEGDPAIYTLPAWTFYGEQLPNHVSWPFLLVPVAGFLFYGWRSRGDRPFTPLTAELQNPVWRNHFNSPFKWLAIFWVGSYVLFSLILNKDFRYVLPYLPVVSLVLAYGLMLFPRNWGKWVRWGTCTAALVLILADVWPVYEWHPDIVASHHAYRGPDWPHQEAIAEIMETTPYLRSTLGVLPSTPMINQHNLNYYGNLQQFQVYGRQVGTRRSHVVQDARSLDWFLTKTGNQGSVPTEAQGAIVELVETGGEFDLQASWPLPDESTLNLYHHRLPMVTVEAVEASATEGMITLDRVTVPAQSPPGVSVPVTYEWTGDWDSLRDGVVILTWQLQNSAASPSLRESWLHDHGIGKGELQAVTAPLQAKVIERMAMLPPADVTAGTYTLAATYLNRKTGETQAIDVPGVAIAINPAAAATPAPELDWSTQLRSLSAALPQGPEALGFIFDDMGRVNQYDPIQDYLIQAEKSLEYRLEQEPNNVELAYNLAFSQVLQQDVDGAIAAFERVVQLDSENPYAHAYLGFVNLYGWHPRQGDPAIKRALELGPNGVEVQLLYGISALMQGNIFATWSRLRGFVPPFLQFGVLLMGWMILFLLGVIFVGIGVKYRKVFKKGFQ
>NC_019693.1|WP_044196302.1|517685_518135_-|hypothetical-protein
MVKSFMLNLRRVSILPATALAIAMSAASVGAQNMYNPIQLPSNNEITDTLSEQDIPTGQGGFARDYIVSLQTGDQIVIDLLSDSFDTIVTLIGPNGMTMAENDDGPDGTTNSLLFARITEGGNYIVRVRAFGEGGTGSFNLKVTRLRPI
>NC_019693.1|WP_015146837.1|516601_517264_-|hypothetical-protein
MKSLWPRWLPYPVSIVRATVVCGVFFLFIRLVASSIQEEVLYWYYYGGGIPDSLIGATFLGWIIILPVVAFLHHWISGVFEERYYQNHHPFIPSWKSCWEGVTALLVATFGFIIVGLVLPSSALRIFWIVSGLWFISMAYLYHIGYLFREWRLVRKAINAERKAARRKANEEARAAKERAKAEKKALKSRRQPAIAPSTETVFDDMLKAIAEKEKRGRRR
>NC_019693.1|WP_083896729.1|515756_516512_+|site-specific-integrase
MADFPTSEVSPTAAKEIRAYLLTNLSQETARRVLQQVSACCRWASEMGMIELNPFEGLPTIKRKKQGSEIYPFTRDERDRILDRFNSDPNHKPFAPYVGFLFLTGCRPSEAIGLQWRHVNCEFVTFAEPVVEGFRESSTKNASIRRFPINKSLAELLESVKPAHPNPILPVFVSSGGGMIRQENFNRRHWRPVLDSLEIPYRRPYNTRHTFATLCLDAGVPVQQVASWLGHSPTMTLKHYAGLTRSEVPEL
>NC_019693.1|WP_156823706.1|515343_515664_+|hypothetical-protein
MRSLCAGDRILRILAASKSNYIMKRQRKGTVGIESNRGWLRLRLPRTASPTGKQQYIYLNLPDNGNSRDIAREKAIEIELDIRRGTLKEINHYLPQVFPHPPVHQG
>NC_019693.1|WP_015146836.1|515126_515336_+|MYND-finger
MDEDYAKYLERQYGPEVAKNYREVSTIKQDHKPFPKCAKCGQIFTHGRKTAYCSKQCEMKTWSKKLTKS
>NC_019693.1|WP_015146834.1|514704_515007_+|hypothetical-protein
MHYFRIPGIKAPKFVIGDQVIATIVDPAEGTFHDPATVTGMVWLGTHWEYFLLFDGYDYSACDWSSNELTLTAKSVNQPRFNRCNHDSAVGLVSSVTNGV
>NC_019693.1|WP_044196303.1|523522_524617_+|phospho-N-acetylmuramoyl-pentapeptide--transferase
MDAKMGSVQSLNLSGTRLFWLLTVAVTGASLILDGLSGRIANLGETLTLPLFACTLATVAVGYWVVPALQRLKTGQVIREDGPQSHLKKAGTPTMGGVFFIPVATLVALIWSGFAPEATAAVALTLSYGFIGWLDDWQILRRKSNKGISPKMKLALQFGFGALFCLGLALTQPPTITNITLPFGIVLPLGFFFWVLAEFVLVAESNATNLTDGVDGLMGGTGAVAFLGLGALVASTHPSLAIFCACISGSCLGFLAYNRNPARVFMGDTGSLALGGALAAVALTSDSLWALFIISGLFFVESLSVIAQVLYYKATKGPDGIGKRLFKMAPIHHHLELSGWSELQIVAAFYVICGVLAILGLTLG
>NC_019693.1|WP_015146844.1|524716_525688_+|glycosyltransferase
MNTQSISQPMPPSFLPQVSVVVPVYNGEKDLPELIDCLRSQTYPPQKVEYILVDNNSSDRTPTLLQEAVQNTPEITLRPLSEPQIQSSYAARNTGIRAATGEFIAFTDADCRPEPNWLFSLIQPFINPQIGIVVGEIAAFPGNNILEQYAEREETLSQKHTLAHPFCPYGQTANLGIRRSIFSEIGLFRSYLTTGGDADICWRILRETEWRLEFAPTAIVKHRHRTTLKELQSQWRRYGKSNRYLHQLHGIDLTRELDQREYLYRLSRWVLKELPLNTLKAVTKKATLADILSTPIGLICIQARSQGQREANLSETARKIDSL
>NC_019693.1|WP_015146845.1|525756_526521_-|HAD-family-hydrolase
MSELRALIFDVDGTLAETERDAHRPAFNRAFKEAGLDWEWSVEFYGELLEIGGGKERIQHYVEQYQSDFPIPNQDLDQFVFDVHEIKNKYFGQLVVDRIPLRPGVMRLMQEAQREGVRLAIATTSDPHNVEALLKSAISPDGPSWFEVIAAGDMVPVKKPEPDVYQYALQALNLQPEDCLAIEDSNQGLLAAQSAGVKTVITVNNYTRKQDFSGAELVIDSLGEPDEPFTVLSGDAGEASYFDLALARQLHQRG
>NC_019693.1|WP_015146846.1|526713_526974_-|DUF1830-domain-containing-protein
MAQLQAPETAIGNSTDILCCYVNITSKIQIIRICNIANWYFERVMFPGQRLLFQAPQQALLEVHTGGTAGAILSDTIPCDRLICDE
>NC_019693.1|WP_156824015.1|527615_528548_+|M48-family-peptidase
MQPIRLKNIRNQQQQVLSAIASIVAHPQNSHSKKQQLLKNLQETVATIEGICTQQNATPAQLSKTSRQTYAWMKFLTDESNLERHLSATRRTQKLAEEMLWSQMQHPCKTITVEFTNITHLYKGKIGPLEAKAQINEAFLNAPDEILAVLVRLAFLGKNQADSQAIKEYALSEDYSEVVLEVDLIADTEAENPQGKCYNLDRLFHTLNREYFGGKMVKPRLSWNRSFTTRKFGHYERGRDRVVLSISLDSDRVPQYVVEFVLYHELLHKHHEGKWVNGRLNVHTPEFRQDEQKFRKYKEADQWLTKLASE
>NC_019693.1|WP_015146848.1|528823_529585_+|hypothetical-protein
MLKKLFIAWQDPLSRAWFVIAQLTHSGESYQFRYLQGVKEAREKTGFKGLFSFPNLEKVYESPELFAFFSNRILRRSRPDYPDYMSWLDLPESEYDPMAMLSRSGGTKVTDHFALFPYPKLDDRGRYHLYFFTHGLRYLPTASADRILTLQVGDRLFLLHDFQNEFDRLALMLRTEDAHLVGYCPRYLREDIFEIFQQNPHAVTITVERVNPPPAFLPMRLLCHLTVDWEGFQPFSSSMYQPLPEAVTILESS
>NC_019693.1|WP_015146849.1|529691_530333_-|SH3-domain-containing-protein
MRKFTQSHLPAAFVSLLAIAGGLLAGTAQTVAASTPSWQQAQATQSFCRRTLTPSGLIIRQGPNPTSPQVGFVPFDEQVTLVQGFQGIQGPDGRQWVEIAAPLRGYVSNGYGNASNLAYCVEQVGTTPVVSTEANPVNLCREVNSDRAPRGLAIRENPSRLSTYKGGVDAAGRVTLVENYQLVRDLNGEPRDWVQITFPINGYISAGSLAACP
>NC_019693.1|WP_015146850.1|530572_531892_-|mechanosensitive-ion-channel-family-protein
MAYLGGFLLGAMMAIASPSFAQEEMEMPPPSPTTEETVPGLTDPFFADVIVQGRPIFQVGSVGNLTARERAQIINRRLSSLMSQSETVDSITVQYNQAENYATLQVNNRVIMTVIEQDSEDFGVENAQVLANQWAEELNRALDRPPLAIDVAQRLNATVRNLLQDAISNLPSLVGALIVILFTWGVAITVRKIAYTWAQQTEGDRSTELLISRLGYGAIWVIGWVIALGVLGLDFAALLGALGLTSVAIGFSLKDVLSNYIAGVILLAVRPFRIGDQIAIGDYEGTVTEVQLRATTIKTYDGRLIYIPNQEVFSSSITNNTASPRRRTSVIVGIDYEADINQAKAAILKALSELDLVERSPAPEVLVQELAASTINLEIRFWVDSRRAEFLEMTSQGAQIIKEALDGVHIEMPTDIYTLTFRNLPPSISSQINSSPPAG
>NC_019693.1|WP_015146851.1|532216_533119_+|DUF928-domain-containing-protein
MAGQKTPLSLIPVGFAVLMAIAIVSRLSTPLQASATAFKIAQETRRGEWLAQEKDILDPPPDDSAPLQGSAGGTRFYQPPLIEPPSQGIPINNGIRGKCPVDRQIPSEPLTALMPSSGVGLTAAENSTTFFIYLPSTSALTGEFVLQDETGTEQLYQMMVELPNTPGIIRLPVPLQELSLNSGEYYRWYFSILCDPSDRAADLFVSGWIQPRDVSPSLMADLENAATPLERAEIYGKNGFWYPNLELLADIQQSSTNFSTEAKNGWDELLNSKVVNLNSLVNQPFVECCEMDNQFLLNPE
>NC_019693.1|WP_015146852.1|533402_535382_+|adenylate/guanylate-cyclase-domain-containing-protein
MFNQKIPKPRFFIGQSPDVTAKKIKQVLWEWRGVFITAPTVALLTIAVRSLGVLQLLEWATLDLFFRWRPVEPTNSRIAIVAISESDIQRAQTWPISDQVLAQLLKTIKSHEPAAIGLDIYRDLPVEPGHEQLAEVFASTPNLIGIQKVIGDFYGDSVAPPSQLSELAQVGAADILLDDDGKVRRVLLSLKDENDKTVYSFAVRLALEYLKPQEIGFKMLDREQYKMGLGKTSFVRLTKNDGGYVGVDTGGIQILFNPRNHLCRNRMHHCNVFDTVSMTAVLENRIPPDFFRDRLVLIGSTAASLKDRFFTSYSNNWITAPAGVEIHAYAVDQLLSGALEGRRSIAVWSDSVEGFWILLWSGFGAILGWRFLRIRSKIMLLALVSGGSIGGGFLVFLAGWWIPIVPPLLALISSAVAMVGYTAYIESENRQTVMNLLGQHVSPKIAQAVWNSRHELLKEGQILGQQMTATVLFTDLQGFTRITEQSDAETLMLWLNEYMKAMSGIVLDHDGVVDKFIGDAIMAVFGVPIPRTRPDEMAGDAIAAVACAVAMGKKLRSLNQQWHAQGRPTVAMRVGISTGTVFAGSLGSRQRLNYTVLGDTVNVAARLESYDKTLDGGICRILIGEETYHYIQGQFPTQCIGSVQLKGREQPVNIYQVLT

Crispr_ID: NC_019693_11

• CRISPR_ID: NC_019693_11
• CRISPR_location: 603093-603201
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_11

Consensus_repeat	Method
CCGGTTTCTGAACCCTTTACCTAGA	CRISPRCasFinder

spacers of NC_019693_11

>11.1|603118|59|NC_019693|CRISPRCasFinder
CCAAGAAACCGGGTTTCTGCGACAATTTTTGCTAATCAACCCAAATTGAGGAAAGAAAT

CRISPR arrays and Neighbor proteins around NC_019693_11

CRISPR arrays

The CRISPR arrays of NC_019693_11

>merge|NC_019693|11|603093-603201|CRISPRCasFinder
CCGGTTTCTGAACCCTTTACCTAGACCAAGAAACCGGGTTTCTGCGACAATTTTTGCTAATCAACCCAAATTGAGGAAAGAAATCCGGTTTCTGAACCCTTTACCTAGA

>NC_019693|11|11|603093-603201|CRISPRCasFinder
CCGGTTTCTGAACCCTTTACCTAGA	CCAAGAAACCGGGTTTCTGCGACAATTTTTGCTAATCAACCCAAATTGAGGAAAGAAAT
CCGGTTTCTGAACCCTTTACCTAGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015146897.1|594513_595734_-|geranylgeranyl-reductase	unknown	unknown	gnl|CDD|177713
NC_019693.1|WP_015146906.1|606579_607572_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|366154
NC_019693.1|WP_015146909.1|611401_612472_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340838
NC_019693.1|WP_015146894.1|591231_592335_+|anthranilate-phosphoribosyltransferase-family-protein	unknown	unknown	gnl|CDD|168934
NC_019693.1|WP_156823710.1|597118_597391_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146912.1|614618_615488_-|dTDP-4-dehydrorhamnose-reductase	unknown	unknown	gnl|CDD|367904
NC_019693.1|WP_015146902.1|601973_602999_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NC_019693.1|WP_015146908.1|609682_611218_-|phosphoglucosamine-mutase	unknown	unknown	gnl|CDD|237671
NC_019693.1|WP_156824016.1|592586_593213_+|molybdenum-cofactor-guanylyltransferase	unknown	unknown	gnl|CDD|235063
NC_019693.1|WP_015146905.1|605365_606538_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NC_019693.1|WP_015146903.1|603212_603956_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_019693.1|WP_015146907.1|607651_609304_-|hypothetical-protein	unknown	unknown	gnl|CDD|279444
NC_019693.1|WP_015146911.1|613536_614610_-|glucose-1-phosphate-thymidylyltransferase	unknown	unknown	gnl|CDD|273500
NC_019693.1|WP_156824017.1|600317_601883_+|peptide-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173884
NC_019693.1|WP_015146896.1|593507_594242_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_019693.1|WP_015146898.1|595941_596442_+|membrane-protein-insertion-efficiency-factor-YidD	unknown	unknown	gnl|CDD|376620
NC_019693.1|WP_015146904.1|604078_605284_-|glycosyltransferase	unknown	unknown	gnl|CDD|340848
NC_019693.1|WP_044196325.1|598017_599907_+|response-regulator	unknown	unknown	gnl|CDD|306677
NC_019693.1|WP_015146910.1|612535_613438_-|glycosyltransferase	unknown	unknown	gnl|CDD|133029
NC_019693.1|WP_015146899.1|596656_597013_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015146897.1|594513_595734_-|geranylgeranyl-reductase	gnl|CDD|177713	PLN00093, PLN00093, geranylgeranyl diphosphate reductase; Provisional.	0
NC_019693.1|WP_015146906.1|606579_607572_-|glycosyltransferase-family-2-protein	gnl|CDD|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	6.86859e-29
NC_019693.1|WP_015146909.1|611401_612472_-|glycosyltransferase-family-4-protein	gnl|CDD|340838	cd03809, GT4_MtfB-like, glycosyltransferases MtfB, WbpX, and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.	1.20206e-103
NC_019693.1|WP_015146894.1|591231_592335_+|anthranilate-phosphoribosyltransferase-family-protein	gnl|CDD|168934	PRK07394, PRK07394, hypothetical protein; Provisional.	0
NC_019693.1|WP_015146912.1|614618_615488_-|dTDP-4-dehydrorhamnose-reductase	gnl|CDD|367904	pfam04321, RmlD_sub_bind, RmlD substrate binding domain. L-rhamnose is a saccharide required for the virulence of some bacteria. Its precursor, dTDP-L-rhamnose, is synthesized by four different enzymes the final one of which is RmlD. The RmlD substrate binding domain is responsible for binding a sugar nucleotide.	2.14794e-137
NC_019693.1|WP_015146902.1|601973_602999_+|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	7.33117e-110
NC_019693.1|WP_015146908.1|609682_611218_-|phosphoglucosamine-mutase	gnl|CDD|237671	PRK14317, glmM, phosphoglucosamine mutase; Provisional.	0
NC_019693.1|WP_015146904.1|604078_605284_-|glycosyltransferase	gnl|CDD|340848	cd03821, GT4_Bme6-like, Brucella melitensis Bme6 and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.	1.40516e-119
NC_019693.1|WP_015146905.1|605365_606538_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	4.08068e-44
NC_019693.1|WP_015146903.1|603212_603956_-|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	4.85201e-23
NC_019693.1|WP_015146907.1|607651_609304_-|hypothetical-protein	gnl|CDD|279444	pfam01098, FTSW_RODA_SPOVE, Cell cycle protein. This entry includes the following members; FtsW, RodA, SpoVE.	0.00417548
NC_019693.1|WP_015146911.1|613536_614610_-|glucose-1-phosphate-thymidylyltransferase	gnl|CDD|273500	TIGR01208, rmlA_long, glucose-1-phosphate thymidylylransferase, long form. The family of known and putative glucose-1-phosphate thymidyltransferase (also called dTDP-glucose synthase) shows a deep split into a short form (see TIGR01207) and a long form described by this model. The homotetrameric short form is found in numerous bacterial species that incorporate dTDP-L-rhamnose, which it helps synthesize, into the cell wall. It is subject to feedback inhibition. This form, in contrast, is found in many species for which it serves as a sugar-activating enzyme for antibiotic biosynthesis and or other, unknown pathways, and in which dTDP-L-rhamnose is not necessarily produced. Alternate name: dTDP-D-glucose synthase.	3.21351e-180
NC_019693.1|WP_156824017.1|600317_601883_+|peptide-ABC-transporter-substrate-binding-protein	gnl|CDD|173884	cd08519, PBP2_NikA_DppA_OppA_like_20, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NC_019693.1|WP_015146896.1|593507_594242_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	7.24601e-88
NC_019693.1|WP_015146898.1|595941_596442_+|membrane-protein-insertion-efficiency-factor-YidD	gnl|CDD|376620	pfam01809, Haemolytic, Haemolytic domain. This domain has haemolytic activity. It is found in short (73-103 amino acid) proteins and contains three conserved cysteine residues.	2.26178e-05
NC_019693.1|WP_156824016.1|592586_593213_+|molybdenum-cofactor-guanylyltransferase	gnl|CDD|235063	PRK02726, PRK02726, molybdenum cofactor guanylyltransferase.	2.25761e-84
NC_019693.1|WP_044196325.1|598017_599907_+|response-regulator	gnl|CDD|306677	pfam00211, Guanylate_cyc, Adenylate and Guanylate cyclase catalytic domain.	2.04424e-77
NC_019693.1|WP_015146910.1|612535_613438_-|glycosyltransferase	gnl|CDD|133029	cd04186, GT_2_like_c, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	2.64344e-35

Protein sequences

>NC_019693.1|WP_015146902.1|601973_602999_+|ABC-transporter-permease
MSRSKALQSYILLRLLLAPLMLWTIATLVFLLLRATPGDPIDAILGPKAPEIEKIRLREQLGLGAPLWLQYIRYMGDLLRLDLGTSLTTRGQTVWEIVGQYFPATLEIAVVSMAVALIVGIGVGVISASNPNTGWDVGGRMFGIITYSLPAFWVGMIMQLIFSVQLGWFPVGARFPSTQTPPSGPTGLYLIDSLFSGNLGNFFTTLHYLALPSLTLGILISGIFERIVRVNLKQTLQADYVEAARARGIPETRIAIAHALKNAMIPVITVMGLTLAALLGGAILTEVTFSWPGLANRLYEAISLRDYPTVQGIVVFFAGIVVIASIGIDLLNAYIDPRIRY
>NC_019693.1|WP_156824017.1|600317_601883_+|peptide-ABC-transporter-substrate-binding-protein
MCCLLAISCGDRPGMNQSNDPNRISIGTTAKIRTIDPADAYENAAGMLLYNLGDRLYTYESGTTTLKPQLATTLPQISPDGVTYTIPLRPDVVYHDGTPFNAETMKFSLQRFMENGGSPSSLLSNIVESVQASGEYELTIQLKQPFAAFSDLLTFSGLVAVSPSAYEIGSGQFKPDTFVGTGPYKLVSYGTDTIRLDVFEDYWGEKPVNTGIDIQQFSSPANVYNSFRRGAVDLTYGTLDLDQISSLERQAPDQGWQVISNRSNGVYVLTLNMQDEALKKLEVRQAIATLIDRPLLQQRIFQGQMEPLYSLIPTTLERYYQPVFQNQYGDGNFAQAQQLLAQAGYTPENPLQLQLWYRSNLRTNADVATTIKAVAEQELGGALQIELQSVEAATAYNNLDKGVYSMFILDWTPDFFDPDNYINPFLSCAKGSVETGCEEGETKLWGSFYYSDRVNQLIARQRQEQNPETRRQIFTELQEILVEDVPFIPLWQGKEYVFARQGIQGATLESTQAVPFWTLKK
>NC_019693.1|WP_044196325.1|598017_599907_+|response-regulator
MNFQDNSEGKADILIVDDVPNNLKLLVNLLRKHNYNVRAVTNGFLALQFVGVRQPDLIFLDIMMPEMDGYEVCEKLKKNPQTKDIPIIFLSALTEGFDKAKAFKSGGIDYISKPFQMEEILARLETHLSQRALQKQLQEKTELLAHQNLQFQAEINERKLLEEKLRSAEEKMRAVFEAMTDIVALISIAEGNISNLDILPSNWMRLYQPDSDIVGQTIEQLFDPETAEIWLNVIGQVLEKRETLHFDYCLTDGGQERWFSAAVSPVREDMVIVVARDISDRKQAEEALKIAEERYHSIVENAIAGIFQSTVEGQYLSVNPALAKIYGYASGEELQQSIKHINTQLYVNPARRQEFIEAVAAKNSVSGFESMVYCKDKSIIWISETARAVRDSSGNILYYEGIVSDITERKLAQEALKFQQNKTEALLLNILPQPIATRLQKGENPIADHFEEVSVIFADLVGFTEFAANRPPKKLLELLNKIFSQFDKLAKHHNLEKIKTIGDAYMVVGGLPVPCAEAIFEVAQMALDMQNELAELNQHTGQTFELRIGIHIGPAIAGVIGMSKFIYDLWGDTVNTASRMESSGLPGKIQVTEAVYERLKDRFEFEERGLISVKGKGEMLTYWLVGNQS
>NC_019693.1|WP_156823710.1|597118_597391_+|hypothetical-protein
MCLHTSALRYRWSSKFKRAIAAFLLRQVTRGIHRTYPVETGDWQRQSSLLWAIPRLHNLSDPEAIALIFLLGVVPFNVIIPKMIPLGRII
>NC_019693.1|WP_015146899.1|596656_597013_-|hypothetical-protein
MPSISLKLPTLRPLRFLLAVCVSALLFFSSAFPAYAASSSPTKGEDQMLKIEEKSLKAIGDDPYTLKDQVDETNPGLNGVQGASDQDKMISPEDAKASGATSFTEQVKNAVENITGKD
>NC_019693.1|WP_015146898.1|595941_596442_+|membrane-protein-insertion-efficiency-factor-YidD
MNSNGLDARLLLDSRLLRAIAIASISGYQKYLSPHKGFSCAHRILYGGDSCSQYIKTAVAQRGLSEAVALSQHRFAACKEAHHILRSQVCAQAQPQKKPNRSSPNRVRDCACTELTPGVGCDACTDSLECLNLLDCCGGITCSDCNPLEDSALDCSTSDCDFGSCG
>NC_019693.1|WP_015146897.1|594513_595734_-|geranylgeranyl-reductase
MALRVAVVGSGPAGSSAAETLAKAGIETYLFERKLDNAKPCGGAIPLCMVSEFDLPDHIIDRRVRKMKMISPSNIEVDINLEKQEEYIGMCRREILDGFLRDRAEKLGANLINGTVHKLDIPSNNTDPYVLHYADHSDGSVAGTQKTLKVDLVIGADGANSRVAKAIDAGDYNYAIAFQERIRLPEDKMAYYNDLAEMYVGTDVSPDFYAWVFPKYDHVAVGTGTMKVNQALIKKLQAGIRTRAAKRLEGGEIIKVEAHPIPEHPRPRRVVGRVALVGDAAGTVTKSSGEGIYFAAKSARMCAETIVEFSEGGTRVPTEEELKIYLKRWDKKYGITYAVLDILQRVFYRTDATREAFVEMCADMDVQRMTFDSYLYKTVVPANPFVQMKITAKTIGSLLRGNALAP
>NC_019693.1|WP_015146896.1|593507_594242_+|response-regulator-transcription-factor
MPRILVIDDDPAISELVAVNLEMAGYEVSQAEDGIKGQALALQLIPDLIMLDLMLPRVDGFTVCQRLRRDERTADIPVLMLTALGQTHDKVEGFNAGADDYLTKPFEVEEMLARVRALLRRTDRIPQAAKHAEILNYGPLTLVPERFEAIWFDRSVKLTHLEFELLHCLLQRHGQTVSPSEILKEVWGYDPDDDIETIRVHVRHLRTKLEPDPRHPRYIKTVYGAGYCLELPNTAPANENPQAV
>NC_019693.1|WP_156824016.1|592586_593213_+|molybdenum-cofactor-guanylyltransferase
MSESSPSNPQLAALILAGGKSSRMGEDKAQILWEGKPLLQRVCEVACHCASQVYYITPWPERYESMLSPEHLSGRTVQALPETDHKKGPLGALSEGLSQIEAEWVLLLACDLPLLDPAIVQQWATQLPHLPPESLALVPKQGTLWHPMCGFYRRSALEPLRQFLEEGGRSFQRWLPQIGATPLEVGTAEFRMLRNFNTPGDLHAPSPE
>NC_019693.1|WP_015146894.1|591231_592335_+|anthranilate-phosphoribosyltransferase-family-protein
MSTVFREFVKKVGSGPHTSQNLSRTEAADAMRMMLLGEATPAQIGAFLIAHRIKRPTGEELAGMLDAYDEIGPKLGAIATSSPVMVWGCPYDGRSRTAPVTVLSAILLASYGQPILLHGGDRMPTKYGIPFVEIWDTLGVNWRTLELKQVHSVLQATGVGFVYLPKQFPEAASLVPYRDQLGKRPPVATLELIWSPYAGDRHLVAGFVHPPTELMFRDALGLRGDSRLTTVKGLEGSCDLPRERTAIIGYSNPSETSPPPAASESDPPHADPFARLLLHPRDYGFTPENVPFQSEAFPAQMQGVLQGEPSELMESAVWSGGFYLWHCGVAGDLSSGITQAREGFKSGRVAAKLQEITQAVSSRSVLD
>NC_019693.1|WP_015146903.1|603212_603956_-|tetratricopeptide-repeat-protein
MWSNTDYGRALGVAILLSLGVTPKVQAIAPSMIENFGQHQIPATVWVAQGMEEFPEAERYYTEGARLQDEGNLEGAITSYQQAIRLNPNFTEAQINMGVALVNLGRISEAIAAYRNAIATNSQLAAAHYNLANALAQQQEFDEAIAAYEEAIRLQPNYDKAYYNMGNILVTRGELQDAISAYQKAIEINPNFAEAYGNLGMILSEGGNQTEATQVLQTARDLFQRQGNFSAVSRIDRLLQQLGTRSN
>NC_019693.1|WP_015146904.1|604078_605284_-|glycosyltransferase
MRILQIIPSISLVYGGPSQMVLGLSAALARQGAEVTILTTNSNGDVGQAPLDVPLNCPVEQDGYQIRYFPCSPFRRYKFSVDLLRWLSINGTEYDIAHLHALFSPVISGAATVARLRKIPYILRPLGTLDPADLRKKNAMKQVYTALWERGNLAGAAAIHFTSAEEAKISERFGVQTRDLIIPLGVSLPGMDRNLTGEERQQRGKKMREELGIASNCPVVLFLSRIEPKKGLDLLLPALEKLLAQGLKFHFVLAGSNPQDPEYEDKIKAQIAASPLAACTSLPGFVRGEFKVSLLQSSDIFVLPSYYENFGIAVAEAMAAGTAVCISRGVYIWEDVVEAGAGWVGNGTVEEIAQLLSEAVSNPQECQKRGEKGQGYAATHYDWDAIAQQTLAAYREILAGE
>NC_019693.1|WP_015146905.1|605365_606538_-|glycosyltransferase-family-4-protein
MKILVASHTYIVDLNREKLRKLAQLAPGIEVTVVVPRRWRPGGVQNQLIETQFLEEGSFRVVPISNFSQNNQGLLTFGADLVSLLRQWHPNIIQVEQGAKAIAYSEFITLNRLLGLKAKNLFFTWWNLPYQLKWPVSVLESYNLRHTDGIIVGNQDGAEILRDRGYSGPLKIMPQLGVDETLFRPHPQPELRTQLAIQPDEFLIGFVGRFVEEKGLLTLLQSLSRLAGKPWKLLLLGRGPLKETLLQKATEFNLQNRLIWIESVPHDEVQRYINLMDVLVLPSETTDKFKTLTSAGWKEQFGHVLIEAMACQVPVIGSDSGEIPNVIQDAGLVFPEGNAEALQDCLGKLMDNPEFAEELGHSGYQRAMKHYTNQALAQQQFEFYQTILEQ
>NC_019693.1|WP_015146906.1|606579_607572_-|glycosyltransferase-family-2-protein
MSLPSISVIIPTYNREKVLRETLADVLQQDYPDFEVLVVDQTPTHEPETDAYLQSLAESHRIQWLRLDWASLPGARNYAVRRSQGEIILFLDDDVQLPPGFLHAHARNYLEQPEIGAIAGRVFDRMKLADSGGGLTIEDLPPEAMDPGIAWYYIDLVHTVKPQQVLSVRGCNMSFRREIFDKYGLHFDERFRGSAVREESDFCLRLRQTGYKIWYEPDAHLIHLGEETGGCHDISTRSISYQITFYHNHFLLGLKNLTLSQCLRFFARLFDCHVLGHPPCNKSGSPIKTLVRGWFYTLGFFNAVGTVLQSSFQDGQIYSQQDELAHSQKT
>NC_019693.1|WP_015146907.1|607651_609304_-|hypothetical-protein
MLKTKQKVNKASQNNHPTQVPTLSKKELAAQQKKRDRERKAMIQSFQTYGGLGAAIGIVLFFVADFKLALAGGGGVAVLLLSYKYPRLAIWGFLIYMPFSGTITYWIGGGNALFQLAKDGFYIPAAIALYREIKSKKLPFLIPSQLGPALNILLLVCLMTLLFVNGAQQFGPRPDGKPIPMGLLGMKVFLGYIPLIGCSYYLIRNKKEFLWLTRTHVILALICCGLGVVQYWLLSSGRCPGTRGYVGEDLFKATLDAKCLVGGSLVFSPEVNMIRLPGTFVAPWQWAWFLIANIFFTFASAFNDPSFLWKMLSFLGMALVFVNSVISGQRIALALVPVLTVILLVVTGQVTNLKRFIPIAVGLSILGFGAMALFPDVVTERIDSFVSRWNASPPTDFIAHQAEFSSKGQAGFFGNGLGKATNSARMFGETKLIETYYPKLLYEIGPVGVIGFLIFVTTLTYLAFKTYRSVKDKNLRGYGASYWVFILFISYNTYYYPLDVDPVAVYYWVFAGLLFKLPDLDREVAQEKLEAEELGLLRNKGSSKKKKKKK
>NC_019693.1|WP_015146908.1|609682_611218_-|phosphoglucosamine-mutase
MVTTPAWTQGSGSNGSSLTLAGVNGSKSVQNPKPTGGKEVINRLSVVETGIYLPNTPLFGTDGIRGRVGDFLNAPLALQVGFWAGQVLKAQSGTTGPIILGQDSRNSSDMLAMALSAGLTSAGLEVWNLGLCPTPCVAYLTSVSEAIGGVMISASHNPPGDNGIKFFGSDGTKLPAAVQKLIEAGIRGQMDSASLTGAWGHQYYRPELVADYAKALQLPLIYGNGTEELPLQGMRIVLDLAWGAAAMLAPEVFEALGAEIICLHDRPDGDRINVGCGSTHLDVLQSTVKAYNADMGFAFDGDADRVLGVDDRGRPIDGDYILYLWGHTLEQSGQLPDSTIVATVMSNLGFERAWEKLGGKLLRTPVGDQHVHAEMLRTGSMLGGEQSGHILCRHYGVTGDGVMTAIHLATVVRQHGGSLAQMVDESFQTYPQLLRNVRVEDRDRRMDWESCEPVQIAINRATAAMGDQGRILVRASGTEPLIRVMVEAATAELTNYWTDNLVRVVEQHLAA
>NC_019693.1|WP_015146909.1|611401_612472_-|glycosyltransferase-family-4-protein
MTSLSINLSFLIPKPTGITTYANQIVPYLTPLEPTLLIGRELAPYNCYLVPEDLTPDYGKKGHLKRLWWTQQHLPKIYKSLRSQLLFSPVPEAPLFSGCRSVVMVHDFIPLRFPNKRSPLTYYHRYYIPLVLQQANHIVCNSISTARDISNFCKISADKITPISLGYDADNFKFLNLPVSNYFLYVGRCDPYKNLHRLIAAFANIAEGSEYELWLAGSSDPRYSPALKEQVKELGLGERVKFLEYVPYEKLPVLMNQAIALVFPSLWEGFGLPALEAMACGTPVITSNRSSLPEVTGDAGILVDPYNIREIASAMLAVALGATTRSRLRELGLARASQFSWSQTGISTGEILKDYL
>NC_019693.1|WP_015146910.1|612535_613438_-|glycosyltransferase
MLYFVTVNYYSTELIEQLIQSIQENSTLEYQVIIVNNSPGDGSIYQLERQSTVILESGENVGFGAGCNLGLDWVYQQDPQGIVWLINPDTLLGSEGWEKVPNLFVANPEVSILGTIVYEPTGTLWFAGGVFIPSQGAILEKNLVNLEADVDYVPCDWVTGCSLLINLGQFSECPTFDPDYFLYYEDFDFCRRYAAQGHIIGVTPKLSLIHSPSSIADTQVKQKFKHSTYSYLKTMEKYSPKRVLISRLFRLIAHGLILIFIKPEIARGKFAGLAQYWQRSPLVQAVLSPLKPRGSDVYFG
>NC_019693.1|WP_015146911.1|613536_614610_-|glucose-1-phosphate-thymidylyltransferase
MKALILSGGKGTRLRPLTYSGAKQLVPVANKPILWYGIEGIVAAGITDIGIIISPETGEEVKSLTGNGDRFGAKITYILQEQPAGLAHAVKIARPFLGDTPFIMYLGDNLIQRPLNPFLDKFKAEQLDALILLRPVSNPSAFGVAKVDEKGKVLALVEKPKDPPSNLALVGIYFFSPQIHEAIANIQPSARGELEITDAIQRLLDWKTSVESCTLEGWWLDTGKKDDLLEANRIILDTQLEAQNHAEVDDHSHIIGRVQIGAGTKVINSSIRGPVIIGENCYLENCFIGPYSSIADQVKLVEADLEHSVVLHSAQIIGIHQRLVDSVIGRRAQLTVAPRRPKALRFMIGDDSQIELP
>NC_019693.1|WP_015146912.1|614618_615488_-|dTDP-4-dehydrorhamnose-reductase
MTQILLTGITGQLGQELSPILQAVGEVTGCDRQTLDLANPDSIHQVMATVKPQVVVNCAAYTAVDKAETEPELAMAINGTGVGILAAECHQLGARLIHVSTDYVFDGTQSHPYGETDTTHPLGQYGASKLAGEEAIRQVGGDAIILRTAWVYGTGGSGNFVKTMLRLGSQREELGVVTDQVGSPTWTGDLAAAIASMIQLAIPSGTYHYTNSGVASWYDFAIAIFEEAQALNFPLQIQRVKPISTEEYPTPARRPAYSVLSLAKIAATLGTYPPHWRQGLRQMLRNFSS

Crispr_ID: NC_019693_12

• CRISPR_ID: NC_019693_12
• CRISPR_location: 690793-690903
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: Cas14u_CAS-V

Consensus repeat of NC_019693_12

Consensus_repeat	Method
GGGCCTGCGCATTGCGCCCCTACACATA	CRISPRCasFinder

spacers of NC_019693_12

>12.1|690821|55|NC_019693|CRISPRCasFinder
TGAACGGGGATGATTTATATTTTGCAATCCCCTTATATTTTGCAATCCCCTTATA

CRISPR arrays and Neighbor proteins around NC_019693_12

CRISPR arrays

The CRISPR arrays of NC_019693_12

>merge|NC_019693|12|690793-690903|CRISPRCasFinder
GGGCCTGCGCATTGCGCCCCTACACATATGAACGGGGATGATTTATATTTTGCAATCCCCTTATATTTTGCAATCCCCTTATAGGGCCTGCGCATTGCGCCCCTACACATA

>NC_019693|12|12|690793-690903|CRISPRCasFinder
GGGCCTGCGCATTGCGCCCCTACACATA	TGAACGGGGATGATTTATATTTTGCAATCCCCTTATATTTTGCAATCCCCTTATA
GGGCCTGCGCATTGCGCCCCTACACATA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015146943.1|676075_676555_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146957.1|697515_701421_+|PAS-domain-containing-protein	unknown	unknown	gnl|CDD|223715
NC_019693.1|WP_015146944.1|676645_677545_-|sugar-kinase	unknown	unknown	gnl|CDD|238920
NC_019693.1|WP_015146961.1|708638_709526_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146960.1|707904_708330_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146952.1|687083_688439_+|30S-ribosomal-protein-S12-methylthiotransferase-RimO	unknown	unknown	gnl|CDD|273453
NC_019693.1|WP_015146955.1|692856_696012_-|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|368641
NC_019693.1|WP_015146953.1|688811_690266_+|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223587
NC_019693.1|WP_015146949.1|682485_683154_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146958.1|702019_703363_-|adenylate-cyclase	unknown	unknown	gnl|CDD|306677
NC_019693.1|WP_015146945.1|677679_678549_+|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	unknown	unknown	gnl|CDD|223390
NC_019693.1|WP_156823714.1|684138_685335_-|DUF21-domain-containing-protein	unknown	unknown	gnl|CDD|224173
NC_019693.1|WP_156823713.1|680987_681158_-|hypothetical-protein	unknown	unknown	gnl|CDD|259851
NC_019693.1|WP_015146959.1|703551_707658_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|378942
NC_019693.1|WP_071884339.1|679239_680436_-|transposase	Cas14u_CAS-V	-	gnl|CDD|223747
NC_019693.1|WP_015146956.1|696425_697208_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_019693.1|WP_156824018.1|709857_710163_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146948.1|681366_682350_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146954.1|692068_692839_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823715.1|701721_701925_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_071884339.1|679239_680436_-|transposase	Cas14u_CAS-V	-	2.8e-29	97.3	0.7

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015146957.1|697515_701421_+|PAS-domain-containing-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	6.11815e-58
NC_019693.1|WP_015146952.1|687083_688439_+|30S-ribosomal-protein-S12-methylthiotransferase-RimO	gnl|CDD|273453	TIGR01125, Ribosomal_protein_S12_methylthiotransferase_RimO, ribosomal protein S12 methylthiotransferase RimO. Members of this protein are the methylthiotransferase RimO, which modifies a conserved Asp residue in ribosomal protein S12. This clade of radical SAM family proteins is closely related to the tRNA modification bifunctional enzyme MiaB (see TIGR01574), and it catalyzes the same two types of reactions: a radical-mechanism sulfur insertion, and a methylation of the inserted sulfur. This clade spans alpha and gamma proteobacteria, cyano bacteria, Deinococcus, Porphyromonas, Aquifex, Helicobacter, Campylobacter, Thermotoga, Chlamydia, Streptococcus coelicolor and Clostridium, but does not include most other gram positive bacteria, archaea or eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification].	0
NC_019693.1|WP_015146955.1|692856_696012_-|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl|CDD|368641	pfam05860, Haemagg_act, haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins.	6.95293e-28
NC_019693.1|WP_015146953.1|688811_690266_+|DEAD/DEAH-box-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	4.24108e-166
NC_019693.1|WP_015146945.1|677679_678549_+|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	gnl|CDD|223390	COG0313, COG0313, Predicted methyltransferases [General function prediction only].	4.52301e-135
NC_019693.1|WP_015146958.1|702019_703363_-|adenylate-cyclase	gnl|CDD|306677	pfam00211, Guanylate_cyc, Adenylate and Guanylate cyclase catalytic domain.	6.33975e-87
NC_019693.1|WP_156823714.1|684138_685335_-|DUF21-domain-containing-protein	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	3.30345e-78
NC_019693.1|WP_156823713.1|680987_681158_-|hypothetical-protein	gnl|CDD|259851	cd00569, HTH_Hin_like, Helix-turn-helix domain of Hin and related proteins. This domain model summarizes a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed helical bundle. The principal DNA-protein interface is formed by the third helix, the recognition helix, inserting itself into the major groove of the DNA. A diverse array of HTH domains participate in a variety of functions that depend on their DNA-binding properties. HTH_Hin represents one of the simplest versions of the HTH domains; the characterization of homologous relationships between various sequence-diverse HTH domain families remains difficult. The Hin recombinase induces the site-specific inversion of a chromosomal DNA segment containing a promoter, which controls the alternate expression of two genes by reversibly switching orientation. The Hin recombinase consists of a single polypeptide chain containing a C-terminal DNA-binding domain (HTH_Hin) and a catalytic domain.	0.00398939
NC_019693.1|WP_015146959.1|703551_707658_-|tetratricopeptide-repeat-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	2.16045e-38
NC_019693.1|WP_071884339.1|679239_680436_-|transposase	gnl|CDD|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.00897e-18
NC_019693.1|WP_015146944.1|676645_677545_-|sugar-kinase	gnl|CDD|238920	cd01945, ribokinase_group_B, Ribokinase-like subgroup B. Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time. .	6.49256e-89
NC_019693.1|WP_015146956.1|696425_697208_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	7.30331e-20

Protein sequences

>NC_019693.1|WP_015146953.1|688811_690266_+|DEAD/DEAH-box-helicase
MTVSFQSLGLSEERVQQLEKLGFTEPSPIQEQAIPKLMAGQDVAGQAQTGTGKTAAFSLPILEQMDVNDKNVQALILAPTRELAIQVSNAIRELTDDRRVRIFAVYGGSSIERQIQRLERGVQIVVGTPGRVLDLLNRGHLKLDTLTHLVLDEADEMLSMGFIDDVEKILARAPKDRQTAFFSATMEPSIRKLMNKFMRDPVTVKIDQQKSTPKQIDQVIYMVPRGWSKSRALLPILELEDPETAIVFVRTRRAAAELTSQLQAAGHSVDEYHGDLNQSQRERLIDRFRKQQVRWIVATDIAARGLDVDHLTHVINYDLPDQVESYVHRIGRTGRAGREGTAISLIQPFDRRKLQQIERHLRQTLKIRSIPTRSQIEARHLEKLQSQVREILSGERLASFLPIVAQLSEEYDPHTIAAAALQMAYDRTRPNWANNISEDAPEEDNYSDKRYDDRGDRSSRSFSKPIKRSKPRNSSSREPIGERQ
>NC_019693.1|WP_015146952.1|687083_688439_+|30S-ribosomal-protein-S12-methylthiotransferase-RimO
MGNKPTIAISHLGCEKNRIDTEHILGLLVQAGYSVDTDEEVADYVIVNTCSFIQSAREESVRTLVELAEANKKIVITGCMAQHFQEQLFDELPEAVAVVGTGDYNKIVEVIERVEVGERVTEISAEPTYIADETTPRYRTTTEGVAYLRVAEGCDYRCAFCIIPHLRGNQRSRTIESIVAEAQQLAAEGVQEIILISQITTNYGLDLYGEPRLAELLRALGEVDVPWIRMHYAYPTGLTPKVLRAIRETPNVLPYLDLPLQHSHPEVLRAMNRPWQAGVNDRIIEGIKAAVPDAVLRTTFIVGFPGETDEHFDHLYQFVQRHEFDHVGVFTFSPEEGTPAYTLPNQLPQEVMDERRDALMELQQPISLKKNQGEVGKVVDVLIEQEHPETGELIGRSARFAPEVDGLVYVRGNARLGSRVPVAIASADVYDLYGHVATVADLVQRESIALG
>NC_019693.1|WP_156823714.1|684138_685335_-|DUF21-domain-containing-protein
MSTTLWIPLILPHYFCPLVISSPLPHLVLAVSQLQPLLGNVWLDVGVLMFMLVLSAMFSGSETAITALDNLKLRSLIKEQGDPHRIFTLVLHKRTRFITTLLVGNNLVNNFSAILTSNLFALWLGNAGLGVATAFVTLLVLIFGEITPKSLAINNVIPIFKVVVRPIYWLSQILSLFGIVQLLEKITQVMIRFVQGNHVQQGESLTDLQLMIEILGGRGQLDLYKHQLLNKALMLDSLSAREVVKPRIEMRTISHEATLQDLVDLCLETGYSRIPVQEESKDRIVGIVHLKRAIQQIRACQQEGIENGGVTLAMDPPVYVPETKRVADLLKEMLQQRLHIAIVVDEYGGTVGLLTLEDILEELVGEIYDESDWDNRIHRKGVLNVGPLGIRSNRGNSR
>NC_019693.1|WP_015146949.1|682485_683154_-|hypothetical-protein
MFILKRQDVEITGIQHPKTGQQIPILNYQGQTFRLINVFSAQQADEARAFWRDLTDNRGKACVLLEETDRYSVWGKIRLDQLTDDAHGGVAAAPLYTQACLLMLQAVFFDIEDLLGNRQAGSFEKDIAETFKKWRFPQAESPDAVNQLLNMDPLGGAQVPSWQEHHLNTLLQELYRLGKAYFGNTSFVERALDILEDMPSAERKQFRDWLGQSPLGEMWSLS
>NC_019693.1|WP_015146948.1|681366_682350_-|hypothetical-protein
MRTTSEKLTSSQPMFTAQTLVVAGIAWAVLALLFFLLFSVPEAPGMGRPLWYSIGTLVFELAAFLGAAILCFRNWRAPQIVSGRNVWLAIGIGMLCYFLGGVLFGLWEQYWNLAPDVSLGDFFYAITYIALTIGMVLAVSGRKLNLEIWQWAVLGAIALAGIALAYWLAVAEPIEVPEATSPQAIEQVAPSANGSGTPAPASSTPQTAPGFIIAIDQALTPVAYYVNLFYVIMDVLLLILATALLLAFWGGRFSQSWRMIAAATFSLYIADMWFKYADVRVANYESGSLLEVFWVFSAVLFGIGAVLEYDISTRSRSRGRRRGGSSD
>NC_019693.1|WP_156823713.1|680987_681158_-|hypothetical-protein
MSSRKLSESDKSDIIDLYRQPGETTLTLASRYGVSSSTISRILKSTLSEELDLITG
>NC_019693.1|WP_071884339.1|679239_680436_-|transposase
MRTSSPSSTALAPDSPEQVNTKLRSKKIRIYPSPELNKVWRKWLAACRYCYNQAIALSRSGKRLSKLKLRNEVMQSDLPAWVKETPCHIRQNAIFDAYLAWIASPGARFRSCRDSSQAIKFNDANFSLGSWYPRLTKGLTFTASEPIPKTCDQGTQLVFAKGRWFAVFPEPVAVTSTEATGVIALDPGVRTFMTGFDGSRFLEFGSGDIGRITRLCQHLDDLMSRIAKEPNRSRRRRMRQAAQRMRTKIRNLVDEAHKQIAHYLTRNYSVIFLPTFETSNMVAKVKRKIRSKTARAMLTWAHYRFKLTLRHQAEITGTTVVDVTEEYTSKTCTHCGHLHSKLGGSKVFRCPECGFTLPRDWNGAFGIFLKALRDTASVTFNGDSAVVALPGNNRTNVA
>NC_019693.1|WP_015146945.1|677679_678549_+|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase
MEIDSKLGTLYIVGTPIGNLEDMTFRAVRILQEVDAIAAEDTRHTGKLLHHFQIKTPQISYHEHNRQQRIPELVNRLVEGAAIALVTDAGMPGISDPGYELVKACLENGIGVVPIPGPSACITAISAAGLPASRFTFEGFLPAKGKERQQQLQGLKGETRAMVLYESPHRLLKTLRDLEKILGGSRALVLGRELTKLHEEFWRGTIAEAVAHYGDNCQPKGEFTLVIDGGDCATPVFSEESLKAALQTAIAQGLTRSEATRQLAEETELPRRQIYQLAIGLDEQNAEDL
>NC_019693.1|WP_015146944.1|676645_677545_-|sugar-kinase
MEESADLKREDETLKKQGLFVGLVTLDVIYLTAGVPQNNQKMVATDSMINAGGPATNAAIAFSYLGNDSTLLAAVGQHPLTAIVYGELEQYGVAIADLDPHRTEPPPLSSIIVTEATGDRAVISINATKSQILGDRLPLDSWSKFNIVLIDGHQMSISQRIAQLMHPQTIPVVLDGGSWKPGFETLLPFVDYALCSSNFYPPNCHNASEVFTYLANLGIPHIAITNGEFPIQYLSQGIPGWVEVPQVKSVDTLGAGDIFHGAFCHYILQETFPRALASAAKIASGACEVFGTRNWMNFT
>NC_019693.1|WP_015146943.1|676075_676555_-|hypothetical-protein
MNTREQFLRLSPRNPWIGWGLGVFYLICACLSLLLIPIGTAMIWIAMTSPLLIIADELCAAIEISNTRIVRRSPLSPRLIIPWKDVKRAILVSNRKNNRLVYIQTREPLRYSLSFNSKQKNFRDGLRRLFEIAEVNRIDIEIKGLSRRRDWKQWAYLKN
>NC_019693.1|WP_015146954.1|692068_692839_+|hypothetical-protein
MNKRSVHVGDLTENFPADIKTDELLGDKLKPAREKYSLRDRLTGLFPVMVAVYLPTFIIVLLVRQQNRVPIHHLMGDPAKIAGWPFYLGMVTKFGILLWCATAAICLFTSLYLKPLSPSLKHQRFILFGGLITTVLMLDDSFQFHEEVFPTYFGIPEKMVYLAYVIMVALYLVKFHKIIWNSRYLLFLGFAFVCFALSILLDMRAIIDLVERGLIYDRDRALLENGFKLFGIVSWFTYFSLTCKEQLQQGMHRWQS
>NC_019693.1|WP_015146955.1|692856_696012_-|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MMLSLIRQVKLNPPWQIHWLLLPFSLGLLCSPSSAQIVPDTTLPVNSIVTPQGDRLVITGGTSTGSNLFHSFTEFNVPTGGTAYFNQGSTLQNIFTRITGINPSNIDGILQANGRANLFLLNPNGIIFGANAQLNIGGSFFASAGDRIQFADRTEFPANPGDNPPLLTVSSPIGLQLGSDPGNITVKDARLQVPTGQQLALVGDNLAISGAQLRAPSGTIDLSAQNTTLSAGALLDVSGEAGGQIRIGSRDITLTDQSRILADTLGNGTGRGIEITTERLNLSDRALISASTFGSGTGGQLTIQATDAVVMTGDNSFNQTLDRLFSNQVTRPDDIGTGIFSLTFNTGNGGNLTLNTPSLQLADSAFISTATFADGNGGNLTVNSGNVHLVESELFADNLGNGDAGDLTLNAQTLTLENGGAIAASTFGAGVGGTITITVSDSIQARGTSSAGRFNSGIFASAYVNATQPAGNIRIQTGQLRVQDGAQIAASTFASVPGGIIAVTASEIEISGISADGRSLSSVKTQTQSEGRAGNLTLNTESLIVRDGAFISTSTLGTGDGGNLTIQATDFVELTGTGTFNLGQAVVEGGFDPDQIQDGLFTVSSVSGNAGNLTLETGRLSVRNGAHIATGTLTQGTGGTLRVRARDRIDLQGAYLLTGTGGSGPAGDIFIDTGDLRLQDRSQIIASTLATGSGGNIQVNAWESVQLQNQSSMISTSQGGGSAGYVLIQTGQLSLQNQSFVSTFASGEGNAGFLGITASESVELQGQSALETFTQGIGDAGFLQIDTRSLTLDNSGISVSAQGTGEAGNLNITTDRLSLNDGFLLGIAASGRGGNVQLEVNDLLTLRQRSAISAEALGTGDGGNVAVATDAIALLENSRIRANAVEGMGGKIQIFTQALFESPESQISASSSQGLDGVVSVNTPDLQPTQGLIALPSEMLNLANLVFEGCGTGASQSEFIVTGRGGLPPNPTDPFNGDRILEDLGTRHSNSDLTPQRFTRDRPAITPPTPSFVEANTWAIAPNGQLILTTAPTSNHPGDRWNTPENCHPRS
>NC_019693.1|WP_015146956.1|696425_697208_+|class-I-SAM-dependent-methyltransferase
MSSEIPITEEHPSEASLEALDSRPEIYPGEVFANVADFDSGIRQLLPIYDELLAALLRCIPVTSQRILELGCGTGELSLKLLAHCPDAELVAVDYSSRMLSVCQDKITAAGYGERVRWIEADFGNLATLNVRIAPHQGFDACASSLAIHHLTDPLKLKLFKWVCQNLSPGGCFWNADPVLSETPALEAVYQAVREEGVTAQGITLEKVRAKCGKSIPQGYSGPDRLATVLEQVELLKSANFATVAIPWKHYGLAVFGGIC
>NC_019693.1|WP_015146957.1|697515_701421_+|PAS-domain-containing-protein
MLEQSRSPIRRYSFAVVTVVLSLLLKFLISSEFMTNNPFLLFSVTVAVSAWYGGFQAGLLATLLAAACGEYFFLLPFYSFGVHSPGQTLALGVFLLEGFAISWLISALYTARQKLEIHALGLENTQEQFRQIAENIDCLIWMTDPEKTEVFYVSPQYEQMWGRSLESLYQQPSSFLEGVHPEDRDRVRTALAKQSSGPYNEEYRTVHPDGTVRWVRSRAFPIRENRTGDVFRVAGIVEDITERKQIEQEFLQANGRYQLASTAVNCVIYDWDLESQQVVRSESLSQLLGFPLAEEEQDAHWWLSLIHPEDLEPAFIAMNKALEHDNRFDIEYRIRHQDGQYLNVSDRGAILRDESGKAVRVIGTTIDISDRKKAEIELQKREELFRTSVENLLDCFGIYTSVRDEVGKIIDFRVEYVNAATCANTGFSREEQQGKRLCDLFPGHRDTGLFDEYCQVVDTRQPLVKDSFVDEKLTTATGVTKAFDIRSVAFGDGFLATWRDITDRKQVEDELYRREREFTALAENSPDIIARFDRKMRPLYVNQAIYRVTGRSPEEFLSTSNLELTFPGTLSPECQAAIAQVFATGEEGEIECELTDIKGGIRYYQSRLVPEFDRDGTVESVLLLSRDITEYKLARATSDRNQERLRLALESAKLGLWDYDLDSQEISVSQRCFDIFGLDLPSNRIQYAQFVECLHPEDRDRVNRAVQRAINEEADYDIEYRIIRTDGILRWIAAKGRAFYDERGTAVRMGGVLLDITERKKAEEERDRLLKQLEFEQQLLKAVLQQMPAGAILAEAPSGKVLLSNKQAQAIWNETIAAEHNLEEYRLFQGLHPDGRPYQPQEFPLSRAIAFGETVIDEEIEIPLTNGHTQIVCLSAKPVKNLAGRIVAGVVMFYDISDRKLAERQREELLLREQEARRQAEAASRMKDEFLAIVSHELRSPLNAILGWSRLLRRRKLNPEKMAQALESIERNAEMQTQLIEDLLDISRIIRGKIRLYLRPLQLIPAIEAAINTVRPTAEIKKIKLVTTLDPGVGLVSGDGDRLQQVVWNLLSNAVKFTPEGGRVEICLERVENWIQIRIIDSGIGIEAEFLPYMFERFQQADSKTTRSHGGLGLGLAIVRNLVELHGGHIFADSPGPGKGSTFVVQLPCLQDTSDGIAEQCLGSSSVECDQSFFLELAGLKILVVDDEFDTREFLITALEQYGAEVFAAASTAEAIALIQEMQPEILLSDIGMPGEDGYTLIRQIRTLPPEQGGQIPAAALTAYTRTEDRILALAAGFQMHIPKPIDPRHLIEVVGQLRNK
>NC_019693.1|WP_156823715.1|701721_701925_-|hypothetical-protein
MSLSMVTHLTSGPLPLARSGLGWGSSWAIATSRTLGGVSACVEPGANLFHRDVRSPLHHDPPLTHSS
>NC_019693.1|WP_015146958.1|702019_703363_-|adenylate-cyclase
MQHDFLENNPVASLLSKVLKSSTSADASRDAEYEAWRDRFMRKRLDVGLWIGLIAFLSASLLQVSNWLFRPEEFRPDWLRSQVSIEICLLLCLLLQHSKLGRRYPSLVFFAFYWVVTIVPQIPRTLSGVAQPELLVWTIMFFGQATFTPVRWYLHLAAQLGVFLYFLGVNSALGVNFSNSISWMKPSVLALYFFWVCFIGNLSVYLYEQLQKAEFKARWDLEEAYAQLEEEQKLSESLLLNVLPHSIATRLKQNPKNLADSYTNVSVLFADIVGFTELSSQISPWDLVELLNQIFSEFDALAELHQLEKIKTIGDAYMVVSGLPEPREDHAQAIADMALDMQRAIATFNNKTGRNFRIRIGIATGPVIAGVIGIKKFIYDLWGDTVNLASRMESHGIPGAIQVTRETYHFLKDEYLFQERGKVFIKGKGEMTTYLLMGKSPGFVERE
>NC_019693.1|WP_015146959.1|703551_707658_-|tetratricopeptide-repeat-protein
MFDNLMEQINSLNRKARTAYDQGQYEQGIQFAKQACELGKYAFGENHPDYARILNVLAHLYRARGRLTDAEPLLLQAMDIFKVQLGEDHPDYATSLNNLAALYYVMGRLTDAERLYRKAMEIIKMQLGENHPNYAGSLNNLASLYHAMGWFTYAERLYRQAMEIIKVQLGENHPDYATSLNNLAGLYQAMGRWTDAERLHWQAMEIIKVQLGENHPDYATSLNNLALLYKAMGQWTDAEPRFRQAMEIIKVQLGENHPSYATSLSNLAGVYYAMGQWTDAEHFYGQAIEIFKVQLGENHPSYAGSLNNLAGVYYAMGRWTDAEHFYGQAMEIIKVQLGEDHPDYATSLSNLAVVYQAMGQWTNAEPLLLQAIKIRKVQLGENHPDYAGSLNNLAALYSVMGRLTDAAPLSLQAMKIIKVQLGENHPSYVTSLHNLAGLYHAMGGVTDAETLHRQSMEIIKVQLGENHPLYTSSLNYLASLYKRMGRWTDAERLYWQAMEIRKVQLGENHPDYATSLNNLASLYQGMGRLTDAKSLHLRAMEIRKVQLGENHPDYADSLNNFAVLMAAMNRPDEAFRLMQEANQITNRIIGDILSISSDRQRLEYMQQNYWQLEEFLSLIIQYFPEDAAAKRAGLDLVLRRKGLATEAGLLMRTLIMSGRYPHLKPELEKLGQLIQQVGAFTLKVPSEPLQYSAYQEQLARLKQEQEDVERSLSRQIPEMNLQTQLDSASREAITQSLPKGATLLEFVRVRVRNFQAVKANGDKQSFPARYLAFVLSAGDAAGVEMIDLGEAEEIDRLCRIFRQSVSGEEQSNSKRDIAFLNLNQAKTPVEEAPSPVVPLIYTTPEGQDLYQKLIAPLKPYVQPHQTVYIAPDGELATLPFGILSGDGSAYLMAEYALRYLSVGRDLLRFQFPIPVDYTASLVIANPDYNLQEDEPLKILEIPSPQPQGSPQTQVQLKRNPPKQPQPIAQEMMLGVGGAIAAITFFILLAVFPPVGIVILCLGMIWLVVVVHKGSYGDRLQEFEAQAREYDRQVTQVQPIPPPPPKKVRPEAISIKPAYIGSDEVRSLSRELGRGSEEVFTPLPGTQIEGSRIAQLLGVPVYTQAQAVKSLLSQCHSPEIVHIATHGYFLPLDQTPPDVWGFFGLPTIEMGGVGSAGMVMQQGRRLQLQGLQDPMRRSGLAFAGANTVLQERLLPEQAEDGLLTAQNAVHLDLTGTRLVVMSACDTALGDQSIGEGVLGLRRSLILAGAETVVMSLWKVPDVPTAILMERFYHNLFETDLGRTVALEKAQEYLKTLQVSQLRQDWLTPEAIEQVGQLNYGSATDLQKLTTKPDDFTPYAGTKYWAAFVCIGNPSPFPKSASLSLPLTRI
>NC_019693.1|WP_015146960.1|707904_708330_+|hypothetical-protein
MNKSSLEKFHQSLQVCKSLKTIQSQRSTLPCEAIHLLCDVAKDPSDLLDLCQQHDSEIEPALTAIADYAARVDNWKAGDCPFGVKDHCNILHFLLNVNTKEFEFFRGRETFTPEIICEFLKDWKGIDLTPLIASREKTSVA
>NC_019693.1|WP_015146961.1|708638_709526_-|hypothetical-protein
MITIAPAKSLQERFLNDFVDKVLPEDGSETQRLCCGLRFHPLNKKKRSSNLTETIQKELKIEFPSTNMPATLGEVIKKIKERFGDAMQADGVPVDLLTGTRGRQRQYPDAKSPWQIIYEWLWEIEFPRQGWKLGQEMATYAIEELQMIELQNGDRDICLNNVAKTPATIHKEKKYALQVDFPHSGHLLLINQGVSGKRYCLCPSLAFSLETQVVPEKKLHIPGIKALASALQYMDMGSEYFLAILTENPVNLSWVHPESNPNDILVTDERLQEIFKQVGRQWNAQVFYKKFEVVE
>NC_019693.1|WP_156824018.1|709857_710163_+|hypothetical-protein
MECVIPNLIGLYIDSYFGCGLSLVLLLWHWTGDKTDRTSNPRQKAIALLPVAIAFCAMNGLGSVPGEPGSVNPGWGTLNRVSLIAVVPPKTKAGFLDTVEF

Crispr_ID: NC_019693_13

• CRISPR_ID: NC_019693_13
• CRISPR_location: 717270-717370
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_13

Consensus_repeat	Method
GGAGGGCCGGAGAGGGGTCCTCCTAGGG	CRISPRCasFinder

spacers of NC_019693_13

>13.1|717298|45|NC_019693|CRISPRCasFinder
CAGCGGGAGCCAGAATACCTCTTAATTTCTCCCTCTCCTCTTAGG

CRISPR arrays and Neighbor proteins around NC_019693_13

CRISPR arrays

The CRISPR arrays of NC_019693_13

>merge|NC_019693|13|717270-717370|CRISPRCasFinder
GGAGGGCCGGAGAGGGGTCCTCCTAGGGCAGCGGGAGCCAGAATACCTCTTAATTTCTCCCTCTCCTCTTAGGGGAGGGCCGGGGAGGGGTCCTCCTAGGG

>NC_019693|13|13|717270-717370|CRISPRCasFinder
GGAGGGCCGGAGAGGGGTCCTCCTAGGG	CAGCGGGAGCCAGAATACCTCTTAATTTCTCCCTCTCCTCTTAGG
GGAGGGCCGGGGAGGGGTCCTCCTAGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015146970.1|722325_723624_+|glutamyl-tRNA-reductase	unknown	unknown	gnl|CDD|234592
NC_019693.1|WP_015146967.1|716303_716585_-|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl|CDD|178809
NC_019693.1|WP_015146969.1|720894_721932_+|class-II-fructose-bisphosphatase	unknown	unknown	gnl|CDD|236536
NC_019693.1|WP_015146960.1|707904_708330_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146966.1|715445_716288_-|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|376806
NC_019693.1|WP_044196361.1|732451_732880_-|DoxX-family-membrane-protein	unknown	unknown	gnl|CDD|226720
NC_019693.1|WP_015146965.1|715037_715364_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146974.1|727995_729582_+|glucose-6-phosphate-isomerase	unknown	unknown	gnl|CDD|237609
NC_019693.1|WP_015146971.1|724180_727222_+|hypothetical-protein	unknown	unknown	gnl|CDD|235047
NC_019693.1|WP_015146958.1|702019_703363_-|adenylate-cyclase	unknown	unknown	gnl|CDD|306677
NC_019693.1|WP_015146961.1|708638_709526_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146963.1|710280_713334_-|SMC-family-ATPase	unknown	unknown	gnl|CDD|223496
NC_019693.1|WP_015146975.1|729675_730389_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_019693.1|WP_015146959.1|703551_707658_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|378942
NC_019693.1|WP_156824018.1|709857_710163_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146973.1|727581_727848_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146972.1|727302_727521_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015146976.1|730524_731217_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|212491
NC_019693.1|WP_015146977.1|731481_731991_-|hypothetical-protein	unknown	unknown	gnl|CDD|178210
NC_019693.1|WP_015146964.1|713798_714971_-|exonuclease-subunit-SbcD	unknown	unknown	gnl|CDD|273178

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015146970.1|722325_723624_+|glutamyl-tRNA-reductase	gnl|CDD|234592	PRK00045, hemA, glutamyl-tRNA reductase; Reviewed.	0
NC_019693.1|WP_015146967.1|716303_716585_-|ATP-dependent-Clp-protease-adapter-ClpS	gnl|CDD|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	6.50697e-44
NC_019693.1|WP_015146964.1|713798_714971_-|exonuclease-subunit-SbcD	gnl|CDD|273178	TIGR00619, Nuclease_SbcCD_subunit_D, exonuclease SbcD. All proteins in this family for which functions are known are double-stranded DNA exonuclease (as part of a complex with SbcC homologs). This complex functions in the initiation of recombination and recombinational repair and is particularly important in regulating the stability of DNA sections that can form secondary structures. This family is likely homologous to the MRE11 family. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	1.61942e-49
NC_019693.1|WP_015146966.1|715445_716288_-|CPBP-family-intramembrane-metalloprotease	gnl|CDD|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	6.22861e-08
NC_019693.1|WP_044196361.1|732451_732880_-|DoxX-family-membrane-protein	gnl|CDD|226720	COG4270, COG4270, Predicted membrane protein [Function unknown].	5.22691e-47
NC_019693.1|WP_015146974.1|727995_729582_+|glucose-6-phosphate-isomerase	gnl|CDD|237609	PRK14096, pgi, glucose-6-phosphate isomerase; Provisional.	0
NC_019693.1|WP_015146971.1|724180_727222_+|hypothetical-protein	gnl|CDD|235047	PRK02509, PRK02509, hypothetical protein; Provisional.	0
NC_019693.1|WP_015146958.1|702019_703363_-|adenylate-cyclase	gnl|CDD|306677	pfam00211, Guanylate_cyc, Adenylate and Guanylate cyclase catalytic domain.	6.33975e-87
NC_019693.1|WP_015146963.1|710280_713334_-|SMC-family-ATPase	gnl|CDD|223496	COG0419, SbcC, ATPase involved in DNA repair [DNA replication, recombination, and repair].	1.49419e-75
NC_019693.1|WP_015146959.1|703551_707658_-|tetratricopeptide-repeat-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	2.16045e-38
NC_019693.1|WP_015146975.1|729675_730389_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.48746e-48
NC_019693.1|WP_015146976.1|730524_731217_-|SDR-family-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.33021e-27
NC_019693.1|WP_015146977.1|731481_731991_-|hypothetical-protein	gnl|CDD|178210	PLN02600, PLN02600, enoyl-CoA hydratase.	0.00353085
NC_019693.1|WP_015146969.1|720894_721932_+|class-II-fructose-bisphosphatase	gnl|CDD|236536	PRK09479, glpX, fructose 1,6-bisphosphatase II; Reviewed.	0

Protein sequences

>NC_019693.1|WP_015146967.1|716303_716585_-|ATP-dependent-Clp-protease-adapter-ClpS
MSVETIEKTSTVRKIAPRYRVLLHNDDFNSMEHVVQTLMQTVPSLTQPQAVSIMMEAHSNGIALVITCALEHAEFYCETLKNHGLTSTIEPDE
>NC_019693.1|WP_015146966.1|715445_716288_-|CPBP-family-intramembrane-metalloprotease
MKLNWIRFGDYPAPGRLAIFVAMLLAVWVPIAVPIYWLIPDPNWVSILSMAVLYGEFILLVRFWGSRVYGQSQILKHYGLEFSRNNGQDLLGGLGFGLLSLLGLLVVEGLLGWLGWQLPDPGGLPKIILEGLAIALGVGFAEELLFRGWLLDELQRDYRPAVAIAANATIFALLHFIKPIEAMIRNLPAFPGLLLLGLTLVTAKRLGQGRLGLPIGFHGGLVCGYYIINTGQLVQYSGAVPEWITGMDQNPIAGISGLVLLSAIAIGMNRAAQFKLKSHT
>NC_019693.1|WP_015146965.1|715037_715364_-|hypothetical-protein
MIQPIRIGTTVFLAIATLAVPGRSQQVTPPSVSREEIVQACVQDRVEVLPPLFSDVPPDHWAFLSVQKISYCGPFRSATPPNLIERLIREEGLLPNPMSLPESPEPTL
>NC_019693.1|WP_015146964.1|713798_714971_-|exonuclease-subunit-SbcD
MRLIHTADWHLGRRLKGIDRTREIAGVLQQILAYAIEWEVDAVLIAGDIFDVPNPPAYAERVAYEFFCGLQAAGIPAVAIAGNHDSATRIDGLATLLSLAGIRALGKPRRGDDGGVITLETKSGPLCVGAMPFASERKMLDAHALWTQDEVVQRQSYREIVADLFADLTQGFRGDRVNVLMGHLAMDGARLAHSEVAYYTRDTYALGEQILPPEAQYIALGHIHIHQKIKASCPTYYSGSLIQIDFGEAEQEKGFCLITVEPGSPAEVEFIPVVCQKPLKVLWCQSDTLNDTLESYQYYPGFLKVMVKLDSPQLGLADRVRQICPQALQIQPLYPEATGNSGQRIRDGNSFDPVEEFGHYYRERLETTPDPLVVQEFQNLYHKLKEKNPG
>NC_019693.1|WP_015146963.1|710280_713334_-|SMC-family-ATPase
MRPLELSLEGFTSFRREQTLDFSELDLFAITGATGAGKSSLLDAMTYALYGTTSRTSQAGELVSQGATTLKVKLRFSVSLGEYRITRTWRYRPSTPVTQVLLERTQADGSWETLETKERESKKAITEILGMDFDTFTRVILLPQGQFDEFLKGNTGKRREILRQLAGFEIFERMRKETNDLARLLKQELATIERQIADLEVPDAIAIQGQRSQLARLETEIPVLNQGVLTAQTLLEAEERLFQQLERLTKFQGQFAELNQKQPEITALSERLARSQVADRLQGDWALVQDARTQDKLATSQAQKAATNLTQAETQFQTEQQKLAEVRAEAAALAPQIAAREEALAQAKAYEEQRQQLEREVAIAATQCQQKQQQQQAAQQELSQGEAQVKAATVQVSLTTDALQQHQPGGDRLERLTTVAPLLVEWTLGEKQRKQQAKALDQVSRDRATGDRTYQAALTRLQQAQEAIGQITQEMAAAETANAEATKSNHAAALRLSLEGGETCPVCGGIHPDSEAELPLLPAIAWVDLTALQTQAATATQALQTAQLNATKAEAALENLTQKQGEIQDQLATLTQQQENLKQQIADVLQQSQAEELDAIALQQERQALERRDRAYREAAEAYQQAISRLETVQQAREFCDRTYQTALTDAQAATEELTRRQHNLQEVREKLAAMTEGLSYQVLAQTLAQQKQTLSSQISAAETAHQTAENRVIQARETAHQAQVTAHATQAKQQQYQTRWQTQLQGANLTEATFLTALASPEEQAKWQQAITHHRESTIELSTRIADLQTEIGDRTTDARQLQQRRQAKQTAEQQLKTAQDKRVELSTWIQSAEQKQAQSEKLLTEQETVSKNYDVYHILAQNLKTNEFQSYILEHLESELVARATLLLKELTESRYALEMQEGEYWVADNWNGGELRRVRTLSGGETFATSLSMAIALSEKLSMGAELGSLFLDEGFGTLDSETLESVTQILESLRQQNRTIGVITHVKSLGERLPTQVKVFKSPQGSRLEVEML
>NC_019693.1|WP_156824018.1|709857_710163_+|hypothetical-protein
MECVIPNLIGLYIDSYFGCGLSLVLLLWHWTGDKTDRTSNPRQKAIALLPVAIAFCAMNGLGSVPGEPGSVNPGWGTLNRVSLIAVVPPKTKAGFLDTVEF
>NC_019693.1|WP_015146961.1|708638_709526_-|hypothetical-protein
MITIAPAKSLQERFLNDFVDKVLPEDGSETQRLCCGLRFHPLNKKKRSSNLTETIQKELKIEFPSTNMPATLGEVIKKIKERFGDAMQADGVPVDLLTGTRGRQRQYPDAKSPWQIIYEWLWEIEFPRQGWKLGQEMATYAIEELQMIELQNGDRDICLNNVAKTPATIHKEKKYALQVDFPHSGHLLLINQGVSGKRYCLCPSLAFSLETQVVPEKKLHIPGIKALASALQYMDMGSEYFLAILTENPVNLSWVHPESNPNDILVTDERLQEIFKQVGRQWNAQVFYKKFEVVE
>NC_019693.1|WP_015146960.1|707904_708330_+|hypothetical-protein
MNKSSLEKFHQSLQVCKSLKTIQSQRSTLPCEAIHLLCDVAKDPSDLLDLCQQHDSEIEPALTAIADYAARVDNWKAGDCPFGVKDHCNILHFLLNVNTKEFEFFRGRETFTPEIICEFLKDWKGIDLTPLIASREKTSVA
>NC_019693.1|WP_015146959.1|703551_707658_-|tetratricopeptide-repeat-protein
MFDNLMEQINSLNRKARTAYDQGQYEQGIQFAKQACELGKYAFGENHPDYARILNVLAHLYRARGRLTDAEPLLLQAMDIFKVQLGEDHPDYATSLNNLAALYYVMGRLTDAERLYRKAMEIIKMQLGENHPNYAGSLNNLASLYHAMGWFTYAERLYRQAMEIIKVQLGENHPDYATSLNNLAGLYQAMGRWTDAERLHWQAMEIIKVQLGENHPDYATSLNNLALLYKAMGQWTDAEPRFRQAMEIIKVQLGENHPSYATSLSNLAGVYYAMGQWTDAEHFYGQAIEIFKVQLGENHPSYAGSLNNLAGVYYAMGRWTDAEHFYGQAMEIIKVQLGEDHPDYATSLSNLAVVYQAMGQWTNAEPLLLQAIKIRKVQLGENHPDYAGSLNNLAALYSVMGRLTDAAPLSLQAMKIIKVQLGENHPSYVTSLHNLAGLYHAMGGVTDAETLHRQSMEIIKVQLGENHPLYTSSLNYLASLYKRMGRWTDAERLYWQAMEIRKVQLGENHPDYATSLNNLASLYQGMGRLTDAKSLHLRAMEIRKVQLGENHPDYADSLNNFAVLMAAMNRPDEAFRLMQEANQITNRIIGDILSISSDRQRLEYMQQNYWQLEEFLSLIIQYFPEDAAAKRAGLDLVLRRKGLATEAGLLMRTLIMSGRYPHLKPELEKLGQLIQQVGAFTLKVPSEPLQYSAYQEQLARLKQEQEDVERSLSRQIPEMNLQTQLDSASREAITQSLPKGATLLEFVRVRVRNFQAVKANGDKQSFPARYLAFVLSAGDAAGVEMIDLGEAEEIDRLCRIFRQSVSGEEQSNSKRDIAFLNLNQAKTPVEEAPSPVVPLIYTTPEGQDLYQKLIAPLKPYVQPHQTVYIAPDGELATLPFGILSGDGSAYLMAEYALRYLSVGRDLLRFQFPIPVDYTASLVIANPDYNLQEDEPLKILEIPSPQPQGSPQTQVQLKRNPPKQPQPIAQEMMLGVGGAIAAITFFILLAVFPPVGIVILCLGMIWLVVVVHKGSYGDRLQEFEAQAREYDRQVTQVQPIPPPPPKKVRPEAISIKPAYIGSDEVRSLSRELGRGSEEVFTPLPGTQIEGSRIAQLLGVPVYTQAQAVKSLLSQCHSPEIVHIATHGYFLPLDQTPPDVWGFFGLPTIEMGGVGSAGMVMQQGRRLQLQGLQDPMRRSGLAFAGANTVLQERLLPEQAEDGLLTAQNAVHLDLTGTRLVVMSACDTALGDQSIGEGVLGLRRSLILAGAETVVMSLWKVPDVPTAILMERFYHNLFETDLGRTVALEKAQEYLKTLQVSQLRQDWLTPEAIEQVGQLNYGSATDLQKLTTKPDDFTPYAGTKYWAAFVCIGNPSPFPKSASLSLPLTRI
>NC_019693.1|WP_015146958.1|702019_703363_-|adenylate-cyclase
MQHDFLENNPVASLLSKVLKSSTSADASRDAEYEAWRDRFMRKRLDVGLWIGLIAFLSASLLQVSNWLFRPEEFRPDWLRSQVSIEICLLLCLLLQHSKLGRRYPSLVFFAFYWVVTIVPQIPRTLSGVAQPELLVWTIMFFGQATFTPVRWYLHLAAQLGVFLYFLGVNSALGVNFSNSISWMKPSVLALYFFWVCFIGNLSVYLYEQLQKAEFKARWDLEEAYAQLEEEQKLSESLLLNVLPHSIATRLKQNPKNLADSYTNVSVLFADIVGFTELSSQISPWDLVELLNQIFSEFDALAELHQLEKIKTIGDAYMVVSGLPEPREDHAQAIADMALDMQRAIATFNNKTGRNFRIRIGIATGPVIAGVIGIKKFIYDLWGDTVNLASRMESHGIPGAIQVTRETYHFLKDEYLFQERGKVFIKGKGEMTTYLLMGKSPGFVERE
>NC_019693.1|WP_015146969.1|720894_721932_+|class-II-fructose-bisphosphatase
MDSVIGLEIIEVVEQAAIASARWMGKGDKNTADHVAVEAMRERMNRIHMRGRIVIGEGERDEAPMLYIGEEVGICTQEDASKFCDPQQLIEIDIAVDPCEGTNLVAYGQNGSMAVLAIAEKGGLFRAPDFYMKKLAAPACAKNHVDINKSATENLKILSDCMSRSIEELVVVVMDRPRHKGLIEEIRNAGARVRLISDGDVSAAISCAFSGTNIHALMGIGAAPEGVISAAAMRCLGGHFQGQLIYDPEVVKTGLIGESKESNIARLQEMGITDPDRVYNAEELASGETVLFAASGITPGTLMQGVRFFKGGARTHSLVISSQSSTARFVDTIHMYDAPKSLQLR
>NC_019693.1|WP_015146970.1|722325_723624_+|glutamyl-tRNA-reductase
MNIAVVGLSHKTAPVEVREKLSIPEADIKEAIAHLCSYPNIREVAILSTCNRLEIYIVTGETDSGVREAIQFLSERGQLNVHKLRQHLFILLQEDAVMHLMRVSAGLDSLVLGEGQILAQVKNTHKLGQQHNGVGRILNRLLKQAITAGKRVRTETSIGTGAVSISSAAVELAQIKVQDLAPYRIAILGAGKMSKLLVQHLLSKGARQITILNRTLRRAEELAKNFPDADLKLHLISDMMTVIGNSDIVFTSTSSTEPILNRSKLEAVLNPNGSMMLIDIAVPRNVDSDVNTLTNVHSFNVDDLKAVVAQNQESRRQMAMEAEGLLEEEVEAFDVWWRSLETVPTISCLRDKIETIREQELEKALSRLGSEFAEKHQEVIEALTRGIVNKILHDPMVQLRAQQDIEARRQAMETLRLLFNLETETRSGEQYS
>NC_019693.1|WP_015146971.1|724180_727222_+|hypothetical-protein
MLKGLGKQAFKWIVAGLALWMGIELFAFLSAESLWFDELGYERVFWVRLLTRLVLLALGLAITGGLTFGNLFLANHLKYGKLDLLSRGLTEPPGGRDRWKRNISHPVERINIPTPHSYTALNLEFLLALVILLAVGISTLLVYYAQVVVDYWHPGSWLLLNSPSVPLGFGLKSGQEMLQQMTTDWWQIALLLLFTVVIVLEPRLLYAIAAALSLFFGLVFSGQWAKVLIFFHPTAFNITEPVFNRDMSFYIFNLPIWELLEFWLLGVLFFVLAAVTILYLISGNSISEGKFPGFSDGQLRHLYGLGAALMGAVALRYWLLRYELLYSSKDVIYGAGYTQVNVEVWSYGGLTLLSGALAIFLLYLTLGVRQLERPNFRRLKQSLGFYVAMVAIAGSVLPFAVQRFIVQPNEIERERPYIERSIAFTRQGFDLDRIDVQLFNPENALTFDDILANDLTINNIRLWDTRPLLQTNRQLQQIRLYYKFADADIDRYTLRKTDPESEESITERQQVLISARELDYSAVPTEAQTWVNEHLVYTHGYGFTLSPVNTVGPGGLPDYFVRDIGMERQTVSETVNDGILGTANELIRASIPIGHPRIYYGELTDTEVMAPSNVPELDYPQGDENVYNTYGGTGGVSIGSWWRRLIFAKYLNNWQMLFTDNFTSETKVLFRRNIKDRVRAIAPFLEFDSDPYLVVANTRLYEPGMTPAEQPFPDDDNYLYWIIDAYTISDRYPYSEPTSQEFNYIRNSVKVVVDAYNGKVKLYIADPSDPLVQSWQEIFPKLLQPLDALPVTLRSHIRYPLDFFDVQSERLLTYHMTDPTVFYNREDQWRVPNEIYGTEQQVVEPYYLIMKLPTEVSEEFILLHPFTPMSRNNLIAWMGGRSDGIHYGNLLLYQFPKQQLVYGPEQIEARINQDPVISQQISLWNRQGSRAIQGNLLVIPIERSLLYVEPLYIEAEQNSLPILARVIVAYENRIVMAETLEQALSAIFQGQGEQQPTDPIIRPVEDLTLPPLN
>NC_019693.1|WP_015146972.1|727302_727521_+|hypothetical-protein
MKLLKKRVRSLLVQLYEEVELLPDDDLQQVGAVVESLYYDLYVLRFIQQANRSVKPGDSLTREEALRYLRSL
>NC_019693.1|WP_015146973.1|727581_727848_+|hypothetical-protein
MILEARYSRSFLLDLRQLDRASFERVYEFVFFKFMQIERIQELPELHQLGAHPIFYRFRLDNYLVAIQVIGHFVKFLRILPLPDLNEP
>NC_019693.1|WP_015146974.1|727995_729582_+|glucose-6-phosphate-isomerase
MDARSLWKRYQDWLYYHEGLGLYLDISRMRFDDAFVESMKPKFAQAFEDMKALENGAVANPDEGRMVGHYWLRNPDIAPTPELKQEILENLSHIEEFAQKVHNGTVHPPSASKFTDILSIGIGGSALGPQFVSTALAPESAPLEIHFIDNTDPAGIDALLNHIKDHLATTLVLVISKSGTTPDTRNGMIEVQKAFESMNLKFADHAVAITGHDSALEKQAQKENWIDIFPMHDWVGGRTSELSGVGLVPAALQGIDIRGMLAGAKEMDDATRQPDLKGNPAALLALSWYFAGNGRGEKDMVVLPYKDSLLLFSRYLQQLVMESLGKEKDLAGNTVYQGIAVYGNKGSTDQHAYVQQLREGVPNFFLTFIEVLEDRQGHSPDVEPGITTGDYLLGFLYGTREAVYDNQRDSISVTIPQVNPRIVGALIALYDRAVGLYASLINVNAYHQPGVEAGKKAASEILNLQTRIMEVIAAEGKPLSLEELAEKADAGDRIEMIYKILRHLHANGRQVTLSGNLAQPASLSVSAR
>NC_019693.1|WP_015146975.1|729675_730389_+|response-regulator-transcription-factor
MPLTILIVDDDPAIRLSICHYLEQCGYSAIAAQNGQEGLLKVEEFQPHLLVTDIIMPEMDGYELVKRVRKKPALRLLPVIFLTARTSTPERILGYKLGCDLYLPKPFDLEELGVVIRNLLERSQLIQSQRQFNADDSPYPPSEPNLNSPSSFDSLPASFNPGTPALTAQESEFAISLTPRERDVLDLLAEGLSNSQIGDRLHLSPRTVEKYVSALLRKTETSNRAGLLRFAIEHHLV
>NC_019693.1|WP_015146976.1|730524_731217_-|SDR-family-oxidoreductase
MKPEAKKWVIVGASRGIGAAVAQHFVSKGDWVISVCRSAPIAGEWVKADVSIPAGIEAIANAVGDAPVDGLLYMGGVWENHAFTEDYDFLKSSDEEMRYVISVNAIAPIEITRKLVNNLSKTKNPRAIFIGSLSGLEHKASREVANTASKFALRGAIQSLRLALRDRNIGFSVINPGNVATAEVLTDIQDGRFPPQKAIPLGDLVSCIDWILSLSPQVDVSEINLEQRTC
>NC_019693.1|WP_015146977.1|731481_731991_-|hypothetical-protein
MARKSKGFGELLKQQQADKSHQKGLEKLEQKVKKGPLGDKFAGMVKNPKGEVKMSEVLEAFVEPYLDFIHDHDEREKLFTLAVMAWNLALMPEKKRPSMIDELLKVGLKGNDPLAQQDTLEIIDELIARKEEFFAKHKRFIVDFQLQDRGNEFHLSVASTFSNALEFPN
>NC_019693.1|WP_044196361.1|732451_732880_-|DoxX-family-membrane-protein
MTSNNNPPNRLKEIFRVVLSVAIIVVGITHFTHPDQYVRIVPPQLPYPTELVYISGFFEILGGIGLLIPFVSVAAAWGLIALFIAVFPANINQALNSIPIEGIPHHPWLYWVRLPFQAVLIAWAWWYTQNPDEQPGSFKEQL

Crispr_ID: NC_019693_14

• CRISPR_ID: NC_019693_14
• CRISPR_location: 982286-982414
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_14

Consensus_repeat	Method
GGTTTCTTGGTCCTTGGGTAGGGGGTTCAGAAACCGGGTTTCT	CRISPRCasFinder

spacers of NC_019693_14

>14.1|982329|43|NC_019693|CRISPRCasFinder
TGCCTAAATTTAGGACAATTAGCAAAAATGGTCGCAGAAACCC

CRISPR arrays and Neighbor proteins around NC_019693_14

CRISPR arrays

The CRISPR arrays of NC_019693_14

>merge|NC_019693|14|982286-982414|CRISPRCasFinder
GGTTTCTTGGTCCTTGGGTAGGGGGTTCAGAAACCGGGTTTCTTGCCTAAATTTAGGACAATTAGCAAAAATGGTCGCAGAAACCCGGTTTCTTAGTCCTTGGGTAGGGGGTTCAGAAACCGGGTTTCT

>NC_019693|14|14|982286-982414|CRISPRCasFinder
GGTTTCTTGGTCCTTGGGTAGGGGGTTCAGAAACCGGGTTTCT	TGCCTAAATTTAGGACAATTAGCAAAAATGGTCGCAGAAACCC
GGTTTCTTAGTCCTTGGGTAGGGGGTTCAGAAACCGGGTTTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015147178.1|977584_981673_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_071884376.1|971266_971575_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147186.1|992878_993268_-|lactoylglutathione-lyase	unknown	unknown	gnl|CDD|272886
NC_019693.1|WP_015147184.1|988051_989059_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|366154
NC_019693.1|WP_015147187.1|993559_994858_+|phosphopyruvate-hydratase	unknown	unknown	gnl|CDD|234617
NC_019693.1|WP_015147174.1|974691_975222_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|227305
NC_019693.1|WP_015147188.1|995342_996401_-|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl|CDD|234761
NC_019693.1|WP_015147189.1|996670_997201_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_019693.1|WP_015147177.1|976916_977561_-|hypothetical-protein	unknown	unknown	gnl|CDD|376390
NC_019693.1|WP_015147176.1|975911_976856_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|227132
NC_019693.1|WP_015147180.1|982707_984684_-|molecular-chaperone-HtpG	unknown	unknown	gnl|CDD|235366
NC_019693.1|WP_015147185.1|989662_992449_-|ATP-dependent-chaperone-ClpB	unknown	unknown	gnl|CDD|274529
NC_019693.1|WP_015147179.1|981957_982194_-|50S-ribosomal-protein-L28	unknown	unknown	gnl|CDD|234736
NC_019693.1|WP_044194442.1|975332_975848_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|227305
NC_019693.1|WP_015147181.1|985171_986032_-|sulfotransferase	unknown	unknown	gnl|CDD|379204
NC_019693.1|WP_015147182.1|986038_987004_-|glycosyltransferase	unknown	unknown	gnl|CDD|313356
NC_019693.1|WP_015147170.1|969221_969815_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147173.1|972097_974407_+|1,4-alpha-glucan-branching-protein-GlgB	unknown	unknown	gnl|CDD|235445
NC_019693.1|WP_015147171.1|970532_970775_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NC_019693.1|WP_015147183.1|987014_987998_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|132997

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015147189.1|996670_997201_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.33059e-13
NC_019693.1|WP_015147184.1|988051_989059_-|glycosyltransferase-family-2-protein	gnl|CDD|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	9.79548e-26
NC_019693.1|WP_015147187.1|993559_994858_+|phosphopyruvate-hydratase	gnl|CDD|234617	PRK00077, eno, enolase; Provisional.	0
NC_019693.1|WP_015147173.1|972097_974407_+|1,4-alpha-glucan-branching-protein-GlgB	gnl|CDD|235445	PRK05402, PRK05402, 1,4-alpha-glucan branching protein GlgB.	0
NC_019693.1|WP_015147188.1|995342_996401_-|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl|CDD|234761	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated.	0
NC_019693.1|WP_015147177.1|976916_977561_-|hypothetical-protein	gnl|CDD|376390	pfam00816, Histone_HNS, H-NS histone family.	0.00268449
NC_019693.1|WP_015147176.1|975911_976856_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|227132	COG4795, PulJ, Type II secretory pathway, component PulJ [Intracellular trafficking and secretion].	2.58052e-08
NC_019693.1|WP_015147180.1|982707_984684_-|molecular-chaperone-HtpG	gnl|CDD|235366	PRK05218, PRK05218, heat shock protein 90; Provisional.	0
NC_019693.1|WP_015147185.1|989662_992449_-|ATP-dependent-chaperone-ClpB	gnl|CDD|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
NC_019693.1|WP_015147179.1|981957_982194_-|50S-ribosomal-protein-L28	gnl|CDD|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	4.96688e-28
NC_019693.1|WP_044194442.1|975332_975848_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|227305	COG4970, FimT, Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion].	3.65541e-11
NC_019693.1|WP_015147181.1|985171_986032_-|sulfotransferase	gnl|CDD|379204	pfam13469, Sulfotransfer_3, Sulfotransferase family.	3.98834e-38
NC_019693.1|WP_015147182.1|986038_987004_-|glycosyltransferase	gnl|CDD|313356	pfam10111, Glyco_tranf_2_2, Glycosyltransferase like family 2. Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.	1.12229e-50
NC_019693.1|WP_015147186.1|992878_993268_-|lactoylglutathione-lyase	gnl|CDD|272886	TIGR00068, Lactoylglutathione_lyase, lactoylglutathione lyase. Lactoylglutathione lyase is also known as aldoketomutase and glyoxalase I. Glyoxylase I is a homodimer in many species. In some eukaryotes, including yeasts and plants, the orthologous protein carries a tandem duplication, is twice as long, and hits this model twice. [Central intermediary metabolism, Amino sugars, Energy metabolism, Other].	6.67565e-77
NC_019693.1|WP_015147174.1|974691_975222_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|227305	COG4970, FimT, Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion].	3.01729e-11
NC_019693.1|WP_015147171.1|970532_970775_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	8.11919e-06
NC_019693.1|WP_015147183.1|987014_987998_-|glycosyltransferase-family-2-protein	gnl|CDD|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	4.20065e-28

Protein sequences

>NC_019693.1|WP_015147179.1|981957_982194_-|50S-ribosomal-protein-L28
MSRKCQLTGKKANNAMAVSHSHRRTHKLQEANLQWKRVWWPQGNRWVRLRISTTAIKTLNNKGLQAYAKEAGINLSKY
>NC_019693.1|WP_015147178.1|977584_981673_-|hypothetical-protein
MATKHKIQKALTRLVQAITRFAQTLTSRNTYRFLRKAFVSYRRRVQAGFVLPTTVLLVLVVTLVIGTLLFRTFQRTEQVAIQRQQQVIYNAATPVLDRARAKLEYLFTGSEYRLGGVPGQDILAGFLQDDRFTLTGETRIDINGGGLDNAWFYQDEKGNRVAYSIILQAPEQQDSLEDLTEAAVAGRADNLQVRTGPMIAPAKLKAGCENVAGSSDSSAVEAGWFDAQNSTAFLYKNFQINVVVINNDGGRRNISTLELEQDREAERGNKWGAWFNSDLEIHPGEPFRWNGAMHSESNIIAANNFTGYLISSPNSCLYDETASDISVADTPDFKGQFLAGAMATNAAEGNSVFNLYDPTNPDATTEPLTAASDSVDAGLPNDVAIDPVALFTDKIHQPRGTVTLSADWEGSALNVGRLKNKKEESPFIDDTYRADDRLGRDTSTEESLIRTKAQALAAGDTRFQTLGYDGYWERRADAEGLRLIVGERLELGNPFGWEQPTLPGGAVNPDADPLFPAASCWGTRCHESLQYKTLRDNLAAVQGMVVYHAGDGSSVTADQEPIACMAMTAHPGTQITIDNSRNFSDNPYSPTNPNINFFTGRGTNGWEFEPPPAAPMANTNWSNALNNLARLAGDPDGAFPPLQEAGRIHPYPQMTMWGNFSNLRRAIPSGENGSLADRSYIDSAACTLGMLAHNVEEIATWPQVYDDTSTLHTELTALVQNSAPTFTFTGNTVTITPASGTPFSVEGYSAIDELPLEAFLSALSSDALREEAWQYHLREQIAYDRSNGTEYSDGTNTCPLATVNDSAGSPVDNPLCPIQFKFPALHYLFPTAAHGEPTTPADDPIGNRDGYITGSNSGTTYEPVDPSQIALTPRAWGSWNTPTAASSTGINTITRPGNTNGTVAFLDKGMYDGRQAMGVRVLDIDLDLLRTGSGGLSNNLWLPHSGIVYAFREDAVREDGIARPGNVALMRVNPSNPSSAQDPPLVNGISPKPVDYYADPDRRPHGFRLQNGRDLSRPASADAPARGLSFISDNPVYIQGDFNLHSTNGTTNNLQEFTTTLQGNWSNFYTRNGLEDRFAKAGTDRWRPSEILADAITLLSSNFCDGSIEDGLRYYPAAPPTNIPTRYGCNAAATYTSYMGMNRVRPQGTPPTVERENTFAPNPADNASGTYPIKINRNGNPLILNGTGNPLGAGEYLTFTTGDCGRPFTRKCIGTPVDNQYNAILIQGIVPSRQNQPYGGLHNFPRTLEFWQNRTLSISGSFLQFNFSTYATGPFDQDTWETTVANSPSGTSINYYFPPLRNWGYDVGLQLAPVPPISERLTAMGSNRSEFYYEPEIDDPYIENLRCASAGGGLVDPSAECN
>NC_019693.1|WP_015147177.1|976916_977561_-|hypothetical-protein
MRLQQLLFERTKSTEQGLTLIECLMGILILTSILVGIAPPLGIVVATRVQNRRAEQAQHLAQAEIDRIRVLVAQRGYTNADLPPLGTDAPTAIRSKLRSPASCSTEDYQNISANELMQVDVNGDCQPDFLVQSLLSNTQGIAGQPPGRFTMTVRVYAGSARNNVGSLSTEQASLKLAGGEGSQRTNPLAVVQTEIFALDSNNVGCILNSSLCIE
>NC_019693.1|WP_015147176.1|975911_976856_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MAKKIFQFLLNRRRVSHPKHFQEGFTLLELLASMMIVSVIITTILALVVDLLGTNQKETAQTETQQEMQRAIDYISSELREAIYIYDNRCFQGNASNPECRGIFNYLTIPANTVPVLAFWKLEPLPENCQLPSADPDDPCKDLRIGGRTYSLVVYYLSTHNPNNTWTGKARIARYQLDKFQSNTVAPELVAGYIDPKPEKFIDWPYQTGSHAVTHANLDILVDFVDVNNEDTDAECPASYELTPSQPFAQSKLGQSNLGFYSCIRQPEDKKAQDALIFIRGNANGKPGVTSDAYLPVLQTQVMRRSVFGLSGNE
>NC_019693.1|WP_044194442.1|975332_975848_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MGINIMKKQLRSRNPTTSGFTLLELLVVVFIIGILSAMGIPSWFSMINRQRVSTAQAQVVQALRSAQTTAKQTRSPQTVTFYPAEVIPTIEISGNKQKLGNGEIKEGMIQLEIPTGTESITFNGEGNVDADSLPFKVVVAGANDNPRRCVLVRTILGAMTQGADGEPVCNP
>NC_019693.1|WP_015147174.1|974691_975222_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MKLPHQIRRRFHQAPANGFTLLEVLIVVFIIAILAALGIPSWLNWVNTLRLNSSQNQIYSALRQAQSQATSNKDIYQVSFREMDDMAQWAVHLSSATLTDQDWQNFNSFIKIDETKTTFYQYASTGVWRMQFNQKGHANGRLGRVTVRLRNSNSNKQRCVFVSTLLGAMRKTEKCG
>NC_019693.1|WP_015147173.1|972097_974407_+|1,4-alpha-glucan-branching-protein-GlgB
MTVKIAPDQVHQIVGNQHQDPFEILGAHPIQDNGKISHWAVRAYLPNADSVSVIVPEQRQEYPMQSVHNPHFFECVIETAELANYQFRITEGEHERVIYDPYAFRSPKLTDLDIHLFAEGNHHRIYEKLGAHTLEVNGVKGVYFAVWAPNARNISVLGDFNHWDGRKHQMAKRGNGVWELFIPDLGVGEHYKYEIKNSAGHIYEKSDPYGFQQEPRPKTASIVTDLDNYNWTDQNWMEERRNSDPLSKPISVYECHLGSWLHASASEPAKLPNGDTEPVVIVSELKPGARFLTYRELAAKLIPYVKELGYTHIELLPIAEHPFDGSWGYQVTGYYAPTSRFGTPEDFMYFVDCCHQEGIGVLVDWVPGHFPKDGHGLAFFDGTHLYEHADPRKGEHKEWGTLVFNYNRNEVRNFLVANVLFWFDKFHIDGIRVDAVASMLYLDYCRKEGEWVTNQYGGRENLEAADFLRQANHLLFSYYPGVLSIAEESTSWPMVSWPTYVGGLGFNLKWNMGWMHDMLDYFSMDPWFRQFHQNNITFSMWYHHSENFMLALSHDEVVHGKSNIIGKMPGDRWQKLANVRCLFTYMFAHPGKKTLFMSMEFGQWSEWNVWGDLEWELLQYEPHQQLKTFMTDLNQLYCSTPELYSQDFGQEGFEWIDCSDNRHSVVSFIRWDKNKEDFVVVVCNFTPQPHSHYRVGVPVHGFYSEIFNSDSGKYGGSNMGNLGGKWADEWWFHSHAYSMDLCLPPLSVLVFKLDQEKTEEARKAWMSQT
>NC_019693.1|WP_071884376.1|971266_971575_+|hypothetical-protein
MQLILVGGILLGITPLAHALPPASDIPEEILRTEIITQGRSPIDGTALTPDEYAALLEDPTVRQMIPAENGSGATAIGPIPPGQIMINRLPVRELLRVIFPF
>NC_019693.1|WP_015147171.1|970532_970775_+|hypothetical-protein
MKNKIASLAVLLALSTSVVACNTNEPETPATTTPTEEVPVDQTAPEAVDTPATTPEATPTTPATTPEATPTTPETAPTAP
>NC_019693.1|WP_015147170.1|969221_969815_-|hypothetical-protein
MRSRPTSAGTSSKVTSIATRQRKAQENLAIAPRTPAQVTPLRSAQPSPRVREGLPPNPKTTEPRKNQAIRNQSTSNPWAIPFWLRSLVKAQTVSSFATFFLVGAALFIYGSTVYYQQQWGTSFRELESLRRQERKLTSTNESLKTQFSKQAEEPSSGLIPPNLNQMIFLKPTPVEAPTAEKSIGEEPPTPDTRPVGY
>NC_019693.1|WP_015147180.1|982707_984684_-|molecular-chaperone-HtpG
MTVLEQGQITIHTENIFPIIKKSLYSDHEIFLRELVSNAVDAIEKLKMVSYAGEFSGDTSNPEITIAVDAEKNTLSITDTGIGMTADEVKQYINQVAFSSAEEFISKYQSASDRQIIGHFGLGFYSAFMVAKTVEIDTLSYKEGAQAVHWSCDGSPSFKLEDSSRTTHGTTITLTLQDEEKEYAEASRIKQLVKTYCDFMPVPIKMDGEQVNRQKALWRESPSSLTDEDYLDFYRYLYPFQEEPLLWVHLNTDYPFLVKGILYFPKLRPDVDVTKGQIKLFCNQVFVSDHCEEIIPKFLLPMRGVLDSPDIPLNVSRSALQMDRTVRKIADFIAKKVADRLKEQYNNNRPEYIRSWQDIGTFVKFGCLNDDKFKKQLEDIIIYRTTADLKPAESDQPAVEVQAEAGDAWKEVSSDSKTEGPSYTTLDEYLERNKARHENQAFYCTDSVAQATYVQLHKSQGLEVLFMDSFIDPHFISFLEREHTEVKFSRVDAEIDDKLIEQDKASEIVDPSTNKTRSEQIKEIFEQALNQPKLTIRTEALKSEDPQGTPPAMVLLPEFLRRLRDMNALVSQESAKFPDEHILLVNTAHPLIQHLTELSQSGIIQGEGKSPSAELADMICHHVYDLALMAQKGFDAEGMTTFVERSNRLLTRLTEQRS
>NC_019693.1|WP_015147181.1|985171_986032_-|sulfotransferase
MEDKKSVVFLVGCARSGTTLLQSILAAHSQVQSFPESKFFLYAVPEQHSKRHKFGLISQRLHSHLEKFFSEVGYPDISKQLPKVPLIRQYTQFFIKKLSQITRENGKTLVLEKTPEHLQYIDYIEKFLSESKLLHIIRNGSDVVASLYELGHKNPKIWGKKYQDIDVCIDRWMGDIEITRRHLHKPNHFLVRYEHLVEDPKAVIQQVCAFIGVEFTENMLEDYRQVSQDLIRDRESWKKTVSGDIKNANSQKFYKVFDEAQQHYILDRLSSVNLDELSSLSTSGDR
>NC_019693.1|WP_015147182.1|986038_987004_-|glycosyltransferase
MPTISVIIPAYNAEKFIKETINSVLNQTFRDFELIVINDGSTDGTLEVVSTFSDSRIQVFSYPNSGPQKSRNRGIDHAKGEYLSFLDADDLWTPDKLERQLQALHDNPDAAVAYSWTDFINGSGERLPGGQHFKFTNDVYERLLLGDFIGSGSNPLIRKDALLNVGPFDESLVGGQDWEMWLRLAAQYQFVVVPSTLVFYRQSGKSWSSNLKRQEQGYQQVIEKSLANAPEKIKKLRKKIMGNRYKFSTFDALRYSRNRQDTLLAARFLWVALKNQPIFLTNKMIWLVLLKIILGLIFSPEGVKTLQVSLRKIKFSTKNPA
>NC_019693.1|WP_015147183.1|987014_987998_-|glycosyltransferase-family-2-protein
MNNSLLDLTVAIPTYNGSPRLPQVLEALRHQINPEKIAWEVIIIDNNSSDETAQVIKDYQRNWPEDSPLEYYFEGQQGLAFARERAIQEAKGTYVAFLDDDNIPAPDWIAAAHEFGKTHPQAGAFSGQIHGEFEVKPPENFNKIAAFLAIREHGSKSFLFDPDNLKLPPGAGLVVRKQAWRDVVPRRTKLRGRIGKEIVAGEDYEVLLYLHQAGWEIWYNPEMHLNHCIPRQRLEREYLLPLARGIGLATCQLRMINAKTRDKPGIWVRTILGNLRRIVQHRLKYGEKLNSELIPSFEMEFYRGSMMSSMVWLNWAINRKLEKDKKK
>NC_019693.1|WP_015147184.1|988051_989059_-|glycosyltransferase-family-2-protein
MGIDLTVVICTYNGENRFPEVLDALFAQVNTEEFSWEILLIDNNSTDNTAQIVRDYQNKFQGIAPLQYCFEPRQGAAHARHRAVKEVNSPLIGFLDDDNIPAKDWVSAAYQFAQEHPKAAAYGSLISPEFEIEPPPNFKRLMPFLAITQRGSKPLLYHSNKNLLPPSAGLVVRTQVWRESVPEHCILSGRTPGSMLTGEDIEALSYIQKQDWEIWYNPAMQVMHKIPRGRLELEYLIPFFRGIGLSRYATRMVRVNPLLRPVFTCAYFANDLRKLMRHILKYGIETTDAIAACERELLVSSLNSFFYLWRNGYLKPDKNHPNELSKNAEMAINKQ
>NC_019693.1|WP_015147185.1|989662_992449_-|ATP-dependent-chaperone-ClpB
MQPTDASKFTDPAWEGIVKSQEVARRYKHQQLEVEHLAIALLEHPEGLAQRILTKAGILPEKLLQQISTFASRQAKVGNTSQLYLGRGLDQLLDKAEIARQNLEDPLISIEHLLLAFAEDDRLGRRALKASTLDARTPFEQQQLDLAIKEIRASAKVKDQTPETEYQALERYGRDLTEQAKQGKLDPVIGRDEEIRRVIQVLSRRTKNNPVLIGEPGVGKTAIAEALAQRIVNGDVPESLKNRQLISLDMGSLIAGAKFRGEFEARLRAVLREVIDSDGQIVLFIDELHTVVGTGAGQGTMDAGNLLKPMLARGELRCIGASTLDEYRKYIEKDAALERRFQQVMVDQPTVDDTISILRGLKERYEVHHGVKILDAALVAAASLSNRYISDRFLPDKAIDLVDEAAAKLKMEITSKPTELEAADRRLMQLEMEKLSLEGEGAGVVGTSAYRASQERLGRITQEIGTLTGKQQQLSNQWQTEKDLLNAINALKEQEDGLRVEIEKAERNYDLNKAAQLKYGKLEVLQRDREAKEAELLKLQASGSTLLREQVTDADIAEIVAKWTGIPINRLLESERQKLLQMESFLHQRVIGQQEAVSAVAAAIRRARAGMKDPGRPIGSFLFMGPTGVGKTELARALSQVLFDTEESLVRLDMSEYMEKHSVSRLVGAPPGYVGYDEGGQLSEVVRRNPYAVVLLDEVEKAHPDVFNILLQVLDDGRITDSQGRLVDFRNTVIVMTSNIGSDHILDLAGDDARYEEMRKRVMMALRKHFRPEFLNRVDEIILFHALTRSQLSEIVKIQVKRLDKLLGEQKISLNLMEEALDYVTEVGYDPVYGARPLKRAIQRELENPIATLLLEGKFVAGDTIYIDRGPTKLVFDTKPPVSKEEKPVVPLSEPPEPSEDSVEEVKTEPLLSRFVDEAIDVKGERIP
>NC_019693.1|WP_015147186.1|992878_993268_-|lactoylglutathione-lyase
MRILHTMLRVGNLEKSLDFYCNVLDMKLLRQKDYPGGKFTLAFVGYRDESEEAAIELTYNWDTDHYDIGTGYGHIALGVDDIYGTCDRIKAKGGKVTREPGPMKHGSTVIAFVEDPNGYKIELIQTKPA
>NC_019693.1|WP_015147187.1|993559_994858_+|phosphopyruvate-hydratase
MNGIDSTAIEVIRAREILDSRGRPTVEAEVYLANGAMGLAQVPSGASTGSFEAHELRDGDKKRYGGKGVAKAVENVENKIAPSLVEMDALDQGAIDYAMIKLDGSPNKSNLGANAILGVSLATAKAGANALQIPLYRYLGGPLANLLPVPLMNVINGGAHAANNVDFQEFMIVPSGASSFKEALRWGAEVFASLSSVLDEKGLLTGVGDEGGFAPNLESNQAALEILMLAIKKAGYKPGEEVSLAMDVAASEFYKDGKYVYEGTAHEPSELIDYLAKLVDEYPIVSIEDGLHEDDWESWKLLTQKLGDRVQLVGDDLFVTNHIRLKRGIEMGAGNAILIKLNQIGTLTETLETIDMATRNGFRSMISHRSGETEDTTIADLAVATRAGQIKTGSLCRSERVAKYNRLLRIEDELGDRAVYAGTVGLGPKGSK
>NC_019693.1|WP_015147188.1|995342_996401_-|N-acetyl-gamma-glutamyl-phosphate-reductase
MGELETMRVGIVGASGYGGVQLVRLIRDHPQLDLVYLGGDSSAGKPFSDLYPHLSQATDLIIESVDVDTIADRCQVVFLSLPNGLAYQMAPRLLEKGCKVLDLSADYRFSNLETYKNWYGGDRADAETAAVAVYGLPELYRDRIKDAQLIGCAGCYPTASILALAPLLKQGMIVPNSAIIDAKSGISGAGRQAKTNLLLAEADNSVAAYGVGRHRHTPEIESIGSDLAGQDILVQFTPHLMPMVRGILSTVYATLRDPGLVREDLVTIYTAFYRNSPWVRVLPAGVFPQTKWAMNSNMCYIGVEIDQRTDRAIVISAIDNLLKGQAGQAIQCLNIMMGWDETLGLPELGFYP
>NC_019693.1|WP_015147189.1|996670_997201_-|GNAT-family-N-acetyltransferase
MGFWKNLFSGSDTSSAPIGAQIEGYQSAGTSDRPGTSPRVYFSTDRDIDLYELEELCDAVGWSRRPLRKVKKAIQYSFLVVSMWEMRGKTRRLIGFSRATSDHAFNATIWDVVVHPEYQGKGFGKSLMNYTIKRLRSEDISNITLFADPHVVEFYRNLGFMSDPEGIKGMFWYPNR

Crispr_ID: NC_019693_15

• CRISPR_ID: NC_019693_15
• CRISPR_location: 984807-984939
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_15

Consensus_repeat	Method
TCAATTTTGAAAAGAGACCTAACCCCCCAGCCCCCTTCCCT	CRISPRCasFinder

spacers of NC_019693_15

>15.1|984848|51|NC_019693|CRISPRCasFinder
ACAAGGGAAGGGGGAGAAAGAGGTAAATTTCCTACTTTTGGCCGGAGGAGT

CRISPR arrays and Neighbor proteins around NC_019693_15

CRISPR arrays

The CRISPR arrays of NC_019693_15

>merge|NC_019693|15|984807-984939|CRISPRCasFinder
TCAATTTTGAAAAGAGACCTAACCCCCCAGCCCCCTTCCCTACAAGGGAAGGGGGAGAAAGAGGTAAATTTCCTACTTTTGGCCGGAGGAGTTCAATTTTGAAAAGAGACCTAACCCCCCAACCCCCTTCCCT

>NC_019693|15|15|984807-984939|CRISPRCasFinder
TCAATTTTGAAAAGAGACCTAACCCCCCAGCCCCCTTCCCT	ACAAGGGAAGGGGGAGAAAGAGGTAAATTTCCTACTTTTGGCCGGAGGAGT
TCAATTTTGAAAAGAGACCTAACCCCCCAACCCCCTTCCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015147178.1|977584_981673_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_071884376.1|971266_971575_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147190.1|997345_997540_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147184.1|988051_989059_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|366154
NC_019693.1|WP_015147187.1|993559_994858_+|phosphopyruvate-hydratase	unknown	unknown	gnl|CDD|234617
NC_019693.1|WP_015147174.1|974691_975222_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|227305
NC_019693.1|WP_015147188.1|995342_996401_-|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl|CDD|234761
NC_019693.1|WP_015147189.1|996670_997201_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_019693.1|WP_015147177.1|976916_977561_-|hypothetical-protein	unknown	unknown	gnl|CDD|376390
NC_019693.1|WP_015147176.1|975911_976856_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|227132
NC_019693.1|WP_015147180.1|982707_984684_-|molecular-chaperone-HtpG	unknown	unknown	gnl|CDD|235366
NC_019693.1|WP_015147185.1|989662_992449_-|ATP-dependent-chaperone-ClpB	unknown	unknown	gnl|CDD|274529
NC_019693.1|WP_015147179.1|981957_982194_-|50S-ribosomal-protein-L28	unknown	unknown	gnl|CDD|234736
NC_019693.1|WP_044194442.1|975332_975848_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|227305
NC_019693.1|WP_015147181.1|985171_986032_-|sulfotransferase	unknown	unknown	gnl|CDD|379204
NC_019693.1|WP_015147182.1|986038_987004_-|glycosyltransferase	unknown	unknown	gnl|CDD|313356
NC_019693.1|WP_015147186.1|992878_993268_-|lactoylglutathione-lyase	unknown	unknown	gnl|CDD|272886
NC_019693.1|WP_015147173.1|972097_974407_+|1,4-alpha-glucan-branching-protein-GlgB	unknown	unknown	gnl|CDD|235445
NC_019693.1|WP_015147171.1|970532_970775_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NC_019693.1|WP_015147183.1|987014_987998_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|132997

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015147189.1|996670_997201_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.33059e-13
NC_019693.1|WP_015147184.1|988051_989059_-|glycosyltransferase-family-2-protein	gnl|CDD|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	9.79548e-26
NC_019693.1|WP_015147187.1|993559_994858_+|phosphopyruvate-hydratase	gnl|CDD|234617	PRK00077, eno, enolase; Provisional.	0
NC_019693.1|WP_015147174.1|974691_975222_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|227305	COG4970, FimT, Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion].	3.01729e-11
NC_019693.1|WP_015147188.1|995342_996401_-|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl|CDD|234761	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated.	0
NC_019693.1|WP_015147177.1|976916_977561_-|hypothetical-protein	gnl|CDD|376390	pfam00816, Histone_HNS, H-NS histone family.	0.00268449
NC_019693.1|WP_015147176.1|975911_976856_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|227132	COG4795, PulJ, Type II secretory pathway, component PulJ [Intracellular trafficking and secretion].	2.58052e-08
NC_019693.1|WP_015147180.1|982707_984684_-|molecular-chaperone-HtpG	gnl|CDD|235366	PRK05218, PRK05218, heat shock protein 90; Provisional.	0
NC_019693.1|WP_015147185.1|989662_992449_-|ATP-dependent-chaperone-ClpB	gnl|CDD|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
NC_019693.1|WP_015147179.1|981957_982194_-|50S-ribosomal-protein-L28	gnl|CDD|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	4.96688e-28
NC_019693.1|WP_044194442.1|975332_975848_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|227305	COG4970, FimT, Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion].	3.65541e-11
NC_019693.1|WP_015147181.1|985171_986032_-|sulfotransferase	gnl|CDD|379204	pfam13469, Sulfotransfer_3, Sulfotransferase family.	3.98834e-38
NC_019693.1|WP_015147182.1|986038_987004_-|glycosyltransferase	gnl|CDD|313356	pfam10111, Glyco_tranf_2_2, Glycosyltransferase like family 2. Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.	1.12229e-50
NC_019693.1|WP_015147186.1|992878_993268_-|lactoylglutathione-lyase	gnl|CDD|272886	TIGR00068, Lactoylglutathione_lyase, lactoylglutathione lyase. Lactoylglutathione lyase is also known as aldoketomutase and glyoxalase I. Glyoxylase I is a homodimer in many species. In some eukaryotes, including yeasts and plants, the orthologous protein carries a tandem duplication, is twice as long, and hits this model twice. [Central intermediary metabolism, Amino sugars, Energy metabolism, Other].	6.67565e-77
NC_019693.1|WP_015147173.1|972097_974407_+|1,4-alpha-glucan-branching-protein-GlgB	gnl|CDD|235445	PRK05402, PRK05402, 1,4-alpha-glucan branching protein GlgB.	0
NC_019693.1|WP_015147171.1|970532_970775_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	8.11919e-06
NC_019693.1|WP_015147183.1|987014_987998_-|glycosyltransferase-family-2-protein	gnl|CDD|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	4.20065e-28

Protein sequences

>NC_019693.1|WP_015147180.1|982707_984684_-|molecular-chaperone-HtpG
MTVLEQGQITIHTENIFPIIKKSLYSDHEIFLRELVSNAVDAIEKLKMVSYAGEFSGDTSNPEITIAVDAEKNTLSITDTGIGMTADEVKQYINQVAFSSAEEFISKYQSASDRQIIGHFGLGFYSAFMVAKTVEIDTLSYKEGAQAVHWSCDGSPSFKLEDSSRTTHGTTITLTLQDEEKEYAEASRIKQLVKTYCDFMPVPIKMDGEQVNRQKALWRESPSSLTDEDYLDFYRYLYPFQEEPLLWVHLNTDYPFLVKGILYFPKLRPDVDVTKGQIKLFCNQVFVSDHCEEIIPKFLLPMRGVLDSPDIPLNVSRSALQMDRTVRKIADFIAKKVADRLKEQYNNNRPEYIRSWQDIGTFVKFGCLNDDKFKKQLEDIIIYRTTADLKPAESDQPAVEVQAEAGDAWKEVSSDSKTEGPSYTTLDEYLERNKARHENQAFYCTDSVAQATYVQLHKSQGLEVLFMDSFIDPHFISFLEREHTEVKFSRVDAEIDDKLIEQDKASEIVDPSTNKTRSEQIKEIFEQALNQPKLTIRTEALKSEDPQGTPPAMVLLPEFLRRLRDMNALVSQESAKFPDEHILLVNTAHPLIQHLTELSQSGIIQGEGKSPSAELADMICHHVYDLALMAQKGFDAEGMTTFVERSNRLLTRLTEQRS
>NC_019693.1|WP_015147179.1|981957_982194_-|50S-ribosomal-protein-L28
MSRKCQLTGKKANNAMAVSHSHRRTHKLQEANLQWKRVWWPQGNRWVRLRISTTAIKTLNNKGLQAYAKEAGINLSKY
>NC_019693.1|WP_015147178.1|977584_981673_-|hypothetical-protein
MATKHKIQKALTRLVQAITRFAQTLTSRNTYRFLRKAFVSYRRRVQAGFVLPTTVLLVLVVTLVIGTLLFRTFQRTEQVAIQRQQQVIYNAATPVLDRARAKLEYLFTGSEYRLGGVPGQDILAGFLQDDRFTLTGETRIDINGGGLDNAWFYQDEKGNRVAYSIILQAPEQQDSLEDLTEAAVAGRADNLQVRTGPMIAPAKLKAGCENVAGSSDSSAVEAGWFDAQNSTAFLYKNFQINVVVINNDGGRRNISTLELEQDREAERGNKWGAWFNSDLEIHPGEPFRWNGAMHSESNIIAANNFTGYLISSPNSCLYDETASDISVADTPDFKGQFLAGAMATNAAEGNSVFNLYDPTNPDATTEPLTAASDSVDAGLPNDVAIDPVALFTDKIHQPRGTVTLSADWEGSALNVGRLKNKKEESPFIDDTYRADDRLGRDTSTEESLIRTKAQALAAGDTRFQTLGYDGYWERRADAEGLRLIVGERLELGNPFGWEQPTLPGGAVNPDADPLFPAASCWGTRCHESLQYKTLRDNLAAVQGMVVYHAGDGSSVTADQEPIACMAMTAHPGTQITIDNSRNFSDNPYSPTNPNINFFTGRGTNGWEFEPPPAAPMANTNWSNALNNLARLAGDPDGAFPPLQEAGRIHPYPQMTMWGNFSNLRRAIPSGENGSLADRSYIDSAACTLGMLAHNVEEIATWPQVYDDTSTLHTELTALVQNSAPTFTFTGNTVTITPASGTPFSVEGYSAIDELPLEAFLSALSSDALREEAWQYHLREQIAYDRSNGTEYSDGTNTCPLATVNDSAGSPVDNPLCPIQFKFPALHYLFPTAAHGEPTTPADDPIGNRDGYITGSNSGTTYEPVDPSQIALTPRAWGSWNTPTAASSTGINTITRPGNTNGTVAFLDKGMYDGRQAMGVRVLDIDLDLLRTGSGGLSNNLWLPHSGIVYAFREDAVREDGIARPGNVALMRVNPSNPSSAQDPPLVNGISPKPVDYYADPDRRPHGFRLQNGRDLSRPASADAPARGLSFISDNPVYIQGDFNLHSTNGTTNNLQEFTTTLQGNWSNFYTRNGLEDRFAKAGTDRWRPSEILADAITLLSSNFCDGSIEDGLRYYPAAPPTNIPTRYGCNAAATYTSYMGMNRVRPQGTPPTVERENTFAPNPADNASGTYPIKINRNGNPLILNGTGNPLGAGEYLTFTTGDCGRPFTRKCIGTPVDNQYNAILIQGIVPSRQNQPYGGLHNFPRTLEFWQNRTLSISGSFLQFNFSTYATGPFDQDTWETTVANSPSGTSINYYFPPLRNWGYDVGLQLAPVPPISERLTAMGSNRSEFYYEPEIDDPYIENLRCASAGGGLVDPSAECN
>NC_019693.1|WP_015147177.1|976916_977561_-|hypothetical-protein
MRLQQLLFERTKSTEQGLTLIECLMGILILTSILVGIAPPLGIVVATRVQNRRAEQAQHLAQAEIDRIRVLVAQRGYTNADLPPLGTDAPTAIRSKLRSPASCSTEDYQNISANELMQVDVNGDCQPDFLVQSLLSNTQGIAGQPPGRFTMTVRVYAGSARNNVGSLSTEQASLKLAGGEGSQRTNPLAVVQTEIFALDSNNVGCILNSSLCIE
>NC_019693.1|WP_015147176.1|975911_976856_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MAKKIFQFLLNRRRVSHPKHFQEGFTLLELLASMMIVSVIITTILALVVDLLGTNQKETAQTETQQEMQRAIDYISSELREAIYIYDNRCFQGNASNPECRGIFNYLTIPANTVPVLAFWKLEPLPENCQLPSADPDDPCKDLRIGGRTYSLVVYYLSTHNPNNTWTGKARIARYQLDKFQSNTVAPELVAGYIDPKPEKFIDWPYQTGSHAVTHANLDILVDFVDVNNEDTDAECPASYELTPSQPFAQSKLGQSNLGFYSCIRQPEDKKAQDALIFIRGNANGKPGVTSDAYLPVLQTQVMRRSVFGLSGNE
>NC_019693.1|WP_044194442.1|975332_975848_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MGINIMKKQLRSRNPTTSGFTLLELLVVVFIIGILSAMGIPSWFSMINRQRVSTAQAQVVQALRSAQTTAKQTRSPQTVTFYPAEVIPTIEISGNKQKLGNGEIKEGMIQLEIPTGTESITFNGEGNVDADSLPFKVVVAGANDNPRRCVLVRTILGAMTQGADGEPVCNP
>NC_019693.1|WP_015147174.1|974691_975222_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MKLPHQIRRRFHQAPANGFTLLEVLIVVFIIAILAALGIPSWLNWVNTLRLNSSQNQIYSALRQAQSQATSNKDIYQVSFREMDDMAQWAVHLSSATLTDQDWQNFNSFIKIDETKTTFYQYASTGVWRMQFNQKGHANGRLGRVTVRLRNSNSNKQRCVFVSTLLGAMRKTEKCG
>NC_019693.1|WP_015147173.1|972097_974407_+|1,4-alpha-glucan-branching-protein-GlgB
MTVKIAPDQVHQIVGNQHQDPFEILGAHPIQDNGKISHWAVRAYLPNADSVSVIVPEQRQEYPMQSVHNPHFFECVIETAELANYQFRITEGEHERVIYDPYAFRSPKLTDLDIHLFAEGNHHRIYEKLGAHTLEVNGVKGVYFAVWAPNARNISVLGDFNHWDGRKHQMAKRGNGVWELFIPDLGVGEHYKYEIKNSAGHIYEKSDPYGFQQEPRPKTASIVTDLDNYNWTDQNWMEERRNSDPLSKPISVYECHLGSWLHASASEPAKLPNGDTEPVVIVSELKPGARFLTYRELAAKLIPYVKELGYTHIELLPIAEHPFDGSWGYQVTGYYAPTSRFGTPEDFMYFVDCCHQEGIGVLVDWVPGHFPKDGHGLAFFDGTHLYEHADPRKGEHKEWGTLVFNYNRNEVRNFLVANVLFWFDKFHIDGIRVDAVASMLYLDYCRKEGEWVTNQYGGRENLEAADFLRQANHLLFSYYPGVLSIAEESTSWPMVSWPTYVGGLGFNLKWNMGWMHDMLDYFSMDPWFRQFHQNNITFSMWYHHSENFMLALSHDEVVHGKSNIIGKMPGDRWQKLANVRCLFTYMFAHPGKKTLFMSMEFGQWSEWNVWGDLEWELLQYEPHQQLKTFMTDLNQLYCSTPELYSQDFGQEGFEWIDCSDNRHSVVSFIRWDKNKEDFVVVVCNFTPQPHSHYRVGVPVHGFYSEIFNSDSGKYGGSNMGNLGGKWADEWWFHSHAYSMDLCLPPLSVLVFKLDQEKTEEARKAWMSQT
>NC_019693.1|WP_071884376.1|971266_971575_+|hypothetical-protein
MQLILVGGILLGITPLAHALPPASDIPEEILRTEIITQGRSPIDGTALTPDEYAALLEDPTVRQMIPAENGSGATAIGPIPPGQIMINRLPVRELLRVIFPF
>NC_019693.1|WP_015147171.1|970532_970775_+|hypothetical-protein
MKNKIASLAVLLALSTSVVACNTNEPETPATTTPTEEVPVDQTAPEAVDTPATTPEATPTTPATTPEATPTTPETAPTAP
>NC_019693.1|WP_015147181.1|985171_986032_-|sulfotransferase
MEDKKSVVFLVGCARSGTTLLQSILAAHSQVQSFPESKFFLYAVPEQHSKRHKFGLISQRLHSHLEKFFSEVGYPDISKQLPKVPLIRQYTQFFIKKLSQITRENGKTLVLEKTPEHLQYIDYIEKFLSESKLLHIIRNGSDVVASLYELGHKNPKIWGKKYQDIDVCIDRWMGDIEITRRHLHKPNHFLVRYEHLVEDPKAVIQQVCAFIGVEFTENMLEDYRQVSQDLIRDRESWKKTVSGDIKNANSQKFYKVFDEAQQHYILDRLSSVNLDELSSLSTSGDR
>NC_019693.1|WP_015147182.1|986038_987004_-|glycosyltransferase
MPTISVIIPAYNAEKFIKETINSVLNQTFRDFELIVINDGSTDGTLEVVSTFSDSRIQVFSYPNSGPQKSRNRGIDHAKGEYLSFLDADDLWTPDKLERQLQALHDNPDAAVAYSWTDFINGSGERLPGGQHFKFTNDVYERLLLGDFIGSGSNPLIRKDALLNVGPFDESLVGGQDWEMWLRLAAQYQFVVVPSTLVFYRQSGKSWSSNLKRQEQGYQQVIEKSLANAPEKIKKLRKKIMGNRYKFSTFDALRYSRNRQDTLLAARFLWVALKNQPIFLTNKMIWLVLLKIILGLIFSPEGVKTLQVSLRKIKFSTKNPA
>NC_019693.1|WP_015147183.1|987014_987998_-|glycosyltransferase-family-2-protein
MNNSLLDLTVAIPTYNGSPRLPQVLEALRHQINPEKIAWEVIIIDNNSSDETAQVIKDYQRNWPEDSPLEYYFEGQQGLAFARERAIQEAKGTYVAFLDDDNIPAPDWIAAAHEFGKTHPQAGAFSGQIHGEFEVKPPENFNKIAAFLAIREHGSKSFLFDPDNLKLPPGAGLVVRKQAWRDVVPRRTKLRGRIGKEIVAGEDYEVLLYLHQAGWEIWYNPEMHLNHCIPRQRLEREYLLPLARGIGLATCQLRMINAKTRDKPGIWVRTILGNLRRIVQHRLKYGEKLNSELIPSFEMEFYRGSMMSSMVWLNWAINRKLEKDKKK
>NC_019693.1|WP_015147184.1|988051_989059_-|glycosyltransferase-family-2-protein
MGIDLTVVICTYNGENRFPEVLDALFAQVNTEEFSWEILLIDNNSTDNTAQIVRDYQNKFQGIAPLQYCFEPRQGAAHARHRAVKEVNSPLIGFLDDDNIPAKDWVSAAYQFAQEHPKAAAYGSLISPEFEIEPPPNFKRLMPFLAITQRGSKPLLYHSNKNLLPPSAGLVVRTQVWRESVPEHCILSGRTPGSMLTGEDIEALSYIQKQDWEIWYNPAMQVMHKIPRGRLELEYLIPFFRGIGLSRYATRMVRVNPLLRPVFTCAYFANDLRKLMRHILKYGIETTDAIAACERELLVSSLNSFFYLWRNGYLKPDKNHPNELSKNAEMAINKQ
>NC_019693.1|WP_015147185.1|989662_992449_-|ATP-dependent-chaperone-ClpB
MQPTDASKFTDPAWEGIVKSQEVARRYKHQQLEVEHLAIALLEHPEGLAQRILTKAGILPEKLLQQISTFASRQAKVGNTSQLYLGRGLDQLLDKAEIARQNLEDPLISIEHLLLAFAEDDRLGRRALKASTLDARTPFEQQQLDLAIKEIRASAKVKDQTPETEYQALERYGRDLTEQAKQGKLDPVIGRDEEIRRVIQVLSRRTKNNPVLIGEPGVGKTAIAEALAQRIVNGDVPESLKNRQLISLDMGSLIAGAKFRGEFEARLRAVLREVIDSDGQIVLFIDELHTVVGTGAGQGTMDAGNLLKPMLARGELRCIGASTLDEYRKYIEKDAALERRFQQVMVDQPTVDDTISILRGLKERYEVHHGVKILDAALVAAASLSNRYISDRFLPDKAIDLVDEAAAKLKMEITSKPTELEAADRRLMQLEMEKLSLEGEGAGVVGTSAYRASQERLGRITQEIGTLTGKQQQLSNQWQTEKDLLNAINALKEQEDGLRVEIEKAERNYDLNKAAQLKYGKLEVLQRDREAKEAELLKLQASGSTLLREQVTDADIAEIVAKWTGIPINRLLESERQKLLQMESFLHQRVIGQQEAVSAVAAAIRRARAGMKDPGRPIGSFLFMGPTGVGKTELARALSQVLFDTEESLVRLDMSEYMEKHSVSRLVGAPPGYVGYDEGGQLSEVVRRNPYAVVLLDEVEKAHPDVFNILLQVLDDGRITDSQGRLVDFRNTVIVMTSNIGSDHILDLAGDDARYEEMRKRVMMALRKHFRPEFLNRVDEIILFHALTRSQLSEIVKIQVKRLDKLLGEQKISLNLMEEALDYVTEVGYDPVYGARPLKRAIQRELENPIATLLLEGKFVAGDTIYIDRGPTKLVFDTKPPVSKEEKPVVPLSEPPEPSEDSVEEVKTEPLLSRFVDEAIDVKGERIP
>NC_019693.1|WP_015147186.1|992878_993268_-|lactoylglutathione-lyase
MRILHTMLRVGNLEKSLDFYCNVLDMKLLRQKDYPGGKFTLAFVGYRDESEEAAIELTYNWDTDHYDIGTGYGHIALGVDDIYGTCDRIKAKGGKVTREPGPMKHGSTVIAFVEDPNGYKIELIQTKPA
>NC_019693.1|WP_015147187.1|993559_994858_+|phosphopyruvate-hydratase
MNGIDSTAIEVIRAREILDSRGRPTVEAEVYLANGAMGLAQVPSGASTGSFEAHELRDGDKKRYGGKGVAKAVENVENKIAPSLVEMDALDQGAIDYAMIKLDGSPNKSNLGANAILGVSLATAKAGANALQIPLYRYLGGPLANLLPVPLMNVINGGAHAANNVDFQEFMIVPSGASSFKEALRWGAEVFASLSSVLDEKGLLTGVGDEGGFAPNLESNQAALEILMLAIKKAGYKPGEEVSLAMDVAASEFYKDGKYVYEGTAHEPSELIDYLAKLVDEYPIVSIEDGLHEDDWESWKLLTQKLGDRVQLVGDDLFVTNHIRLKRGIEMGAGNAILIKLNQIGTLTETLETIDMATRNGFRSMISHRSGETEDTTIADLAVATRAGQIKTGSLCRSERVAKYNRLLRIEDELGDRAVYAGTVGLGPKGSK
>NC_019693.1|WP_015147188.1|995342_996401_-|N-acetyl-gamma-glutamyl-phosphate-reductase
MGELETMRVGIVGASGYGGVQLVRLIRDHPQLDLVYLGGDSSAGKPFSDLYPHLSQATDLIIESVDVDTIADRCQVVFLSLPNGLAYQMAPRLLEKGCKVLDLSADYRFSNLETYKNWYGGDRADAETAAVAVYGLPELYRDRIKDAQLIGCAGCYPTASILALAPLLKQGMIVPNSAIIDAKSGISGAGRQAKTNLLLAEADNSVAAYGVGRHRHTPEIESIGSDLAGQDILVQFTPHLMPMVRGILSTVYATLRDPGLVREDLVTIYTAFYRNSPWVRVLPAGVFPQTKWAMNSNMCYIGVEIDQRTDRAIVISAIDNLLKGQAGQAIQCLNIMMGWDETLGLPELGFYP
>NC_019693.1|WP_015147189.1|996670_997201_-|GNAT-family-N-acetyltransferase
MGFWKNLFSGSDTSSAPIGAQIEGYQSAGTSDRPGTSPRVYFSTDRDIDLYELEELCDAVGWSRRPLRKVKKAIQYSFLVVSMWEMRGKTRRLIGFSRATSDHAFNATIWDVVVHPEYQGKGFGKSLMNYTIKRLRSEDISNITLFADPHVVEFYRNLGFMSDPEGIKGMFWYPNR
>NC_019693.1|WP_015147190.1|997345_997540_+|hypothetical-protein
MAYPFMIVQWQVATYADRQEDANPSSKEMARLKSLGVGGIEGPKFQPKARENLNPPWRSAQCLP

Crispr_ID: NC_019693_16

• CRISPR_ID: NC_019693_16
• CRISPR_location: 1248094-1248192
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_16

Consensus_repeat	Method
GAAATCGGCGCGACTTCCTCTACAGGCGGTTGT	CRISPRCasFinder

spacers of NC_019693_16

>16.1|1248127|33|NC_019693|CRISPRCasFinder
CCAGATGCCTGAGGGGTGGGGGGTAAAGGGTCG

CRISPR arrays and Neighbor proteins around NC_019693_16

CRISPR arrays

The CRISPR arrays of NC_019693_16

>merge|NC_019693|16|1248094-1248192|CRISPRCasFinder
GAAATCGGCGCGACTTCCTCTACAGGCGGTTGTCCAGATGCCTGAGGGGTGGGGGGTAAAGGGTCGGAAATCGGCGCGACTTCCTCTACAGGCGGTTGT

>NC_019693|16|16|1248094-1248192|CRISPRCasFinder
GAAATCGGCGCGACTTCCTCTACAGGCGGTTGT	CCAGATGCCTGAGGGGTGGGGGGTAAAGGGTCG
GAAATCGGCGCGACTTCCTCTACAGGCGGTTGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015147396.1|1246415_1247120_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
NC_019693.1|WP_015147394.1|1245200_1245614_+|DUF393-domain-containing-protein	unknown	unknown	gnl|CDD|225556
NC_019693.1|WP_015147404.1|1256404_1256656_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147392.1|1244187_1244712_+|mechanosensitive-ion-channel	unknown	unknown	gnl|CDD|366370
NC_019693.1|WP_044196481.1|1241374_1243975_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|227328
NC_019693.1|WP_015147389.1|1237164_1240341_+|S-layer-family-protein	unknown	unknown	gnl|CDD|368641
NC_019693.1|WP_015147408.1|1259505_1259946_-|DUF4079-domain-containing-protein	unknown	unknown	gnl|CDD|372553
NC_019693.1|WP_015147399.1|1249391_1250600_-|putative-calcium-binding-protein	unknown	unknown	gnl|CDD|349398
NC_019693.1|WP_083896848.1|1257940_1258636_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224058
NC_019693.1|WP_015147395.1|1245616_1246111_+|nucleoside-deaminase	unknown	unknown	gnl|CDD|223663
NC_019693.1|WP_015147384.1|1226167_1227604_+|cobyrinate-a,c-diamide-synthase	unknown	unknown	gnl|CDD|234896
NC_019693.1|WP_015147405.1|1257115_1257898_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_019693.1|WP_156823740.1|1228340_1230209_+|BamA/TamA-family-outer-membrane-protein	unknown	unknown	gnl|CDD|225387
NC_019693.1|WP_015147402.1|1255482_1255746_+|BolA/IbaG-family-iron-sulfur-metabolism-protein	unknown	unknown	gnl|CDD|227340
NC_019693.1|WP_156824027.1|1250772_1250910_+|DUF3079-domain-containing-protein	unknown	unknown	unknown
NC_019693.1|WP_015147400.1|1251324_1253490_-|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173822
NC_019693.1|WP_044196491.1|1255861_1256185_+|Grx4-family-monothiol-glutaredoxin	unknown	unknown	gnl|CDD|188046
NC_019693.1|WP_015147390.1|1240821_1241166_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147393.1|1244808_1245123_+|glutaredoxin-3	unknown	unknown	gnl|CDD|239510
NC_019693.1|WP_044196495.1|1258795_1259335_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015147396.1|1246415_1247120_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	4.84896e-31
NC_019693.1|WP_015147394.1|1245200_1245614_+|DUF393-domain-containing-protein	gnl|CDD|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.0302e-31
NC_019693.1|WP_015147392.1|1244187_1244712_+|mechanosensitive-ion-channel	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	3.07576e-25
NC_019693.1|WP_044196481.1|1241374_1243975_+|CHAT-domain-containing-protein	gnl|CDD|227328	COG4995, COG4995, Uncharacterized protein conserved in bacteria [Function unknown].	9.91e-141
NC_019693.1|WP_015147389.1|1237164_1240341_+|S-layer-family-protein	gnl|CDD|368641	pfam05860, Haemagg_act, haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins.	9.75749e-25
NC_019693.1|WP_015147408.1|1259505_1259946_-|DUF4079-domain-containing-protein	gnl|CDD|372553	pfam13301, DUF4079, Protein of unknown function (DUF4079). This is an uncharacterized family of proteins.	7.58051e-30
NC_019693.1|WP_015147399.1|1249391_1250600_-|putative-calcium-binding-protein	gnl|CDD|349398	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins. Little is known about bacterial and archaeal members of the CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family. The wider family of CAP domain containing proteins includes plant pathogenesis-related protein 1 (PR-1), cysteine-rich secretory proteins (CRISPs), and allergen 5 from vespid venom, among others. Studies of eukaryotic proteins show that CAP domains have several functions, including the binding of cholesterol, lipids and heparan sulfate. This group includes Borrelia burgdorferi outer surface protein BB0689, which does not bind to cholesterol, lipids, or heparan sulfate, and whose function is unknown.	2.09748e-38
NC_019693.1|WP_083896848.1|1257940_1258636_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	6.7517e-65
NC_019693.1|WP_015147395.1|1245616_1246111_+|nucleoside-deaminase	gnl|CDD|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	2.21358e-68
NC_019693.1|WP_015147384.1|1226167_1227604_+|cobyrinate-a,c-diamide-synthase	gnl|CDD|234896	PRK01077, PRK01077, cobyrinate a,c-diamide synthase.	0
NC_019693.1|WP_015147405.1|1257115_1257898_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.71601e-72
NC_019693.1|WP_156823740.1|1228340_1230209_+|BamA/TamA-family-outer-membrane-protein	gnl|CDD|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	8.1498e-120
NC_019693.1|WP_015147402.1|1255482_1255746_+|BolA/IbaG-family-iron-sulfur-metabolism-protein	gnl|CDD|227340	COG5007, COG5007, Predicted transcriptional regulator, BolA superfamily [Transcription].	3.39765e-23
NC_019693.1|WP_015147400.1|1251324_1253490_-|S8-family-serine-peptidase	gnl|CDD|173822	cd07498, Peptidases_S8_15, Peptidase S8 family domain, uncharacterized subfamily 15. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	2.47465e-92
NC_019693.1|WP_044196491.1|1255861_1256185_+|Grx4-family-monothiol-glutaredoxin	gnl|CDD|188046	TIGR00365, TIGR00365, monothiol glutaredoxin, Grx4 family. The gene for the member of this glutaredoxin family in E. coli, originally designated ydhD, is now designated grxD. Its protein, Grx4, is a monothiol glutaredoxin similar to Grx5 of yeast, which is involved in iron-sulfur cluster formation. [Energy metabolism, Electron transport].	9.99523e-63
NC_019693.1|WP_015147393.1|1244808_1245123_+|glutaredoxin-3	gnl|CDD|239510	cd03418, GRX_GRXb_1_3_like, Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide reductase. It contains a redox active CXXC motif in a TRX fold and uses a similar dithiol mechanism employed by TRXs for intramolecular disulfide bond reduction of protein substrates. Unlike TRX, GRX has preference for mixed GSH disulfide substrates, in which it uses a monothiol mechanism where only the N-terminal cysteine is required. The flow of reducing equivalents in the GRX system goes from NADPH -> GSH reductase -> GSH -> GRX -> protein substrates. By altering the redox state of target proteins, GRX is involved in many cellular functions including DNA synthesis, signal transduction and the defense against oxidative stress. Different classes are known including E. coli GRX1 and GRX3, which are members of this subfamily.	2.21633e-42

Protein sequences

>NC_019693.1|WP_015147396.1|1246415_1247120_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MQIPLLKSPIQSEKNPSVNSKISPWLASALYPLGRFVVLPAYFKEIEVIGREHIPTNGPTILAPTHRSRWDGILVAYAAGRHITGRDLRYMVSVDEFKGIYSWLIPRVGGFPIDRKRPGIASLRHGVELLEVGEMLAIFAEGAIFRDGKLHPLKPGLARLAIQAESLHPNLGVKIVPMNLEYQPTIPEWRSQVKITIAPPLEVSQYCLDTPKESGNQLTSDLEIALRAIGQGPR
>NC_019693.1|WP_015147395.1|1245616_1246111_+|nucleoside-deaminase
MGVQDPQYLIHRDWMSQAIALAQAAGDAGEVPVGAIVVDPSGKAVARTENRRERDHDPTAHAEILALRTAGQVLQNWHLNGCTLYVTLEPCPMCAGAIAQSRLSLLVYGADDPKSGAIRTVLNLPDSPASFHRLSVLGGILESDCRDQLQSWFSQRRQSHGTKL
>NC_019693.1|WP_015147394.1|1245200_1245614_+|DUF393-domain-containing-protein
MTYFFIYDGKCNLCVSVVQLLETFDKGDIFRYIPMQDEDSLSRLGVTPKDCEQGMILIDADRPERRWQGSDAAEELGNLLPGGSLFVSAYRALPGMKWTGDRVYEQIRDNRYQLFGQRTDIYHSTYPGDCETCNYPT
>NC_019693.1|WP_015147393.1|1244808_1245123_+|glutaredoxin-3
MLNFLNRLLGRHPENIKAHVEIYTWQTCPYCIRAKVLLMWKGVKFTEYKIDGDGAARVKMAERANGRRSVPQIFINDRHIGGCDDLYELDAKAQLDPLLIMASN
>NC_019693.1|WP_015147392.1|1244187_1244712_+|mechanosensitive-ion-channel
MLDPLLNLIIIGAPRVGGSLLIIISFWIATVLLRKLIRRFSITSNLSLDALKLLEQTLISTVWIVGIVTALGTVGIDVSALIAGLGLTGFAVGLALKDILSNLVSGALILIYRPFRRRDRISVGNFEGTVIDIDLRYTTLQGEGKTILIPNSYLFTNTICVIQDSGVKIITKIY
>NC_019693.1|WP_044196481.1|1241374_1243975_+|CHAT-domain-containing-protein
MKMRHPQPMPLSHVKQGLLLSVGLFWLALPLGAIAQTPEELVEQGRQLYQSGEFSAAAAVWETAASRSDGEGNRLQQAVALSNLSAALQELGEWEEAKAAIGQSLALIEAESDSPASVRVLAQVLNTRGGLEFTLGQTEAAVTTWEQAADAYRQAGEKSGEYRAMINQARALQALGLYRRSVTRLEQLQTQLAQETDSDTKVTALLALGNALRLVGDLKESETVLRDSLATAQRLKSPAAISESAIALGNTVRARQDGNAALALYQQAASTAESADTQVQARLNALSLLIENPLILSDSASEPLIQSWIPQIQAQIEALPPSRMAVYARIKFAQSWVQWHEGKSSLSSVLPEAAQLLGTAVQQAKSIGDRRAESYALGNLGELYERDRQWQQAQILTQQALELAEHINAMDIAYRWEWQLGRVLLAIGDRPGAVIAYSQAVNSLESLRLDLVTTNREVQFSFRDSVEPVYRELVALLLDVPSPSQNPTSSSGVSQENLQKALQAIESLKLAELDNFFRDACVDSNAVQLDKQQVDLTAAIVYPIVLDDRLEVIVSLPNQPLQHYSTPLPKEEIEETLITLRRSLVTRTSRQYRVYANTVYNWLVAPIQDSLANSGIKTLVFVPDGLFRNIPMAALYDGEQFLLEKYSVAVSPGLKLTEPQPLRRQSLKALTAGLTEERFGFAQLPNVALEVEQINTALSGIVLMDNGFTRDTLQQQLLQTPFPVVHIATHGQFSSSAEDTFILAWDDRINVNELDSLLRGRNRNNNNEALELLVLSACQTATGDNRAALGLAGMAVRAGARSTLATLWYIDDAATVPLMIDFYTFLTQDNLTKSESLRQAQLNLLRQAEYQHPIYWAAYVLVGNWL
>NC_019693.1|WP_015147390.1|1240821_1241166_+|hypothetical-protein
MLSHHAPDEQDYWSETVEIETVDGEKVKVKTSLLRVYPSGFNGYDAYMDIPKNTPHDPYKFKKVYFPKLDIHWEVITTPTESGIKGDFRGNHTPTSNIPGNTPAWIFGLRNCSN
>NC_019693.1|WP_015147389.1|1237164_1240341_+|S-layer-family-protein
MPGRLQSRSQYSVKAIALHFTALSMGSLACLSPATAQIIPDSTLPNNSVVVPNGNSITIQGGTESGVNLFHSFSEFSVPTNTEAFFNNSPTIQNIFTRITGSNFSEIDGLIRANGLANLFVLNPNGIAFGPNARINIGGSFIGSTANSLQFPDGSTFSASEPNAPPLLTMSVPVGLQFNSNAGNIQVQGTGNPDIVPSNPQGMGVAPGQTFALVGGNVSLNGAVITVPSGRIEIGGVTDGGVDVVPTPGGMVLGYDRVAEFGNIQLSDRSSLFNPAVADNPIAGIQVVGKNIGLERSQIVAVTPGTFDSGNIAINARESLSLSGVDSIFPFSSWIVNQVAQNATGNSGSVIVNAPVTNLTDGSRIQTLSSGAGNAGNVTVNAEKLAIAGFAIPFTGIPDIREVDRKTLLDRNLNSRIGSENFASGSGGEITVNATEINLIDGGQINSLAGSTSTGNGATVTVSANSITGDNAVAYNPLVSSGIFSYLVGAGQGGNVNISAVEIMIANGAQIGTLSEGTGPGGDLNVTASESILLQKVNPSVPVFATGLFVSTSDTGEGGNMSLSTPRLTLTEGAGLSSIVFAPFLGQPLPTGGQGNGGDVTVNADTIVISGATPLNPENVSQMGSITFGSGNAGDVTISTRRLDINEGAILLSLVVPSLSVLGEPIPGSGTGNGGNLTIQASEEINVVGVNPLLRSASLMGLQTFGSGNVGELQVTSERIFLKDGGSMGAFTSGTGNAGQITVNASEIELGGVSSGGFVLSTLGANAFQATPELQQIFFSPPVPTGNTGAVTINADRIRIGDTGTITVTHAGTGNAGTLQINASEISVDGQGSITATTASGRGGNVELNVQNGLILTNNSRISVEALGDGGDGGNVAIAANTIVALENSLIRANAVSGNGGNINIVTQGLFLSPDSQITASSQFGLDGTIEVQEPALDPASGLVELEDNPTDPRDRIVSGCAVQEGSRFLVTGRGGLPENPNQPFMGSAVWHDLRTMAIHREAQGPEPALQSPVAMKAEPLVETTGWAIDERGNLVLTATPRNRYRLFPDSCSSSSPD
>NC_019693.1|WP_156823740.1|1228340_1230209_+|BamA/TamA-family-outer-membrane-protein
MPTINLPQHPRSDQRQNTPASFTGSGFAREPGESPYESRKTTRLIRLTLTLLLLLGGNGGALLAQTTNPGTLTDPSRIPNPLPPSSPQLPERPPLLPPPDELLQPPTTDPAAPPLQVDPTGEIPGAIEVQRFEVFDSTVFSNEIWAEILAPFTDRPLSFAELLQARTAVTQRYTQEGYITSGALIPPQTLEDGVVRIQVVEGGLEEINVTGNQRLSPNYVSSRLAIATEKPVNIDQLLDALRLLQLDPRIENISAELAAGSRPGQNVLDVRITEASAFGSEFVLDNGRSPSVGSFRQKGTVYHRNLFGFGDTLNFSYTNTEGSNQWDVGYTLPINARNGTFSVSHGRTQSEIIEPPFDRVDIEAKSRNTEFTLRQPLIQSPTREFAMGLTFARRSSETSILGVNFPLSPGANDDGETRISAFRFFQEWTARSSREVLAARSQFNLGVGWFDATVNSSAPDSRFLSWRGQGQWLRVLGSETSDPQRSPTLLVRGDVQLSSGSLLPLEQFGLGGLESVRGYRQDALLTDNGVIASAELRIPVYRQNWFGVQVVPFVDVGTAWNSGDGDNPDPNTLASAGLGLQLDFGDRLRARLDWGYPLIDSPSRERTWQENGFYFSIVSSPF
>NC_019693.1|WP_015147384.1|1226167_1227604_+|cobyrinate-a,c-diamide-synthase
MTTIIAGERSGVGKTTITLAMLAYLQRQGLKVQSFKVGPDYIDPMFHHYVTGRPCRNLDPVLTSPEYVQDCFNRHSPLTEFSLIEGVMGLFDGVQPAPLLMDSSPVFSLGDFSSTAHIARLLQLPVILVLDCSRLSSSIAAIAQGYRTLDPRVKIAGVILNRVGSDRHLELLQDALATIQFPVLGVWRRQDNITIPDRHLGLIPTAELPQLDALIDRLAHLAETCFDWEQLFPLLTSTPATAVKPLEIPPCQGLKSKIPIAIAQDAAFNFYYQDNIDSLESLGVEWVPWSPLQDTVLPEGVQGLYLGGGFPEIFAETLAKNTSALRSVYQAVASGMPTYAECGGLMYLSQNIVDFNGKSWPMVGIFPTNAVMGSRLSLGYRLATTLQDTPLLRTGETVWGHEFHRSHLTTEPASPLFQLQGFHRKSAVTPEGWGYSPQIATPAIHASYLHLHWGGQWQIPQRFLQHCQGFIPESRAFL
>NC_019693.1|WP_015147399.1|1249391_1250600_-|putative-calcium-binding-protein
MTSAFLNRVVELTNVERSQQGLAPLTLNPQLAAAAQVHSANMGMRDFLDHINPFDGTVAADRVTLQGYNYQTVAENVAGGQPTPEQTVLEWMNSPSHRVNILNPAVTEIGVGYHFQENDTGNVNFSHYWTQVFATPLEDPWPPQPRPIVPLHTPTPPPTDGITLISQPLTPNNQGFFDLTANAEGVQLAPGALNGYPLGLRALDGDDIIIGSSEGEVINGNSGRDRIYGTGGNNFLRGGKGDDSLFGGAGNDIINGNNDNDVVFGGEGNDILRGGKGHDYLYGESGDDVLIGDFGADVLIGGAGADLFVLRRDTAVGVVEPQMADYILDFNPAQGDRIGLTGGLTQNDISYQRFVDVDNNGIPDALIQINSTNEILGVVLNINPLELNGMFVTVSPEVLAMG
>NC_019693.1|WP_156824027.1|1250772_1250910_+|DUF3079-domain-containing-protein
MLWQQDLRVNFHRVCWNCCNYCALVLIYSGENNNSCKHPLEILYF
>NC_019693.1|WP_015147400.1|1251324_1253490_-|S8-family-serine-peptidase
MTGPVYRSDASQSNPVGIGVSDQSLGILLQRGGEELLLLKLSDRFTVRPLEPNAPKDWFSQIPATHQQQLPNTQLEEFIVDEADLEKVMTAVRSLPEVAFVSHVYTVDNNPQMRVYLTDEVTIQFAQTVDETQRQAIADAVQLDLDKPVYGIPNTFISYVRRTATENPIKIANRLMRKSEVLTAEPNIVITTQNHYLPRSSFYHKQWYLHNKGGRDLAPGSHIEAEKAWDITRGIRSVVVAIADDAIDLNHPDFQGPGKVVAPRDFKRKNFLPLPEEDSDNHGTACAGVAVAEENGIGIVGVAPGCALMPIRTTGYLDDESIEQVFDWAMTKGASVISCSWGASAVYFPLSLRQRAAITRAATEGRNGKGCVIVFAAGNANRPTSGTVNESGWPNNLLKGSVKWLSGFAVHPDVITVSACTSLAKKAAYSNWGPSISVCAPSNNAPPGMWIQEMGAVNTPPEIKGYLTGLGIFTTDRTGSKGYDSGDYTGYFGGTSSACPVVAGVAALVLSVNPHLTAAQVKQILEQSADKIIDPDIDIQLGNRFGTYDSKGHSQWFGYGKVNAYNAVRRAQRLFAMPMQVTRQVQVENNRRQAIPDFQRNQSGLFPLNLFGSSDRPGLISEISIADPSAVVDIRVTVDIQHSYLGDLEVYLIAPNGHTMQLQSRTLGNQTRLNKTYSLQTTPTLRQLCHQSAKGSWKLWVRDCVPGDTGTLNRWDLTLAV
>NC_019693.1|WP_015147402.1|1255482_1255746_+|BolA/IbaG-family-iron-sulfur-metabolism-protein
MVSPDQVKAMIETQLPDAQVTVEDLTGTRDHYQVIVVSSHFEGLPRVRQHQLVYGSLQEAMSTEAIHALTMKTYTPEAWSQVSGAVS
>NC_019693.1|WP_044196491.1|1255861_1256185_+|Grx4-family-monothiol-glutaredoxin
MTPELKERLDNIVKRNKITVFMKGTKLMPQCGFSNNVVQILNTLGVPYETVNVLDDYEIRQGIKEYSNWPTIPQVYVNGEFVGGSDILIELYQSGELQQMVEVALAS
>NC_019693.1|WP_015147404.1|1256404_1256656_-|hypothetical-protein
MLQDTATIRHYQKLTDSLVDMWNRGYRLDDLRLYLEGYIAALRQTNTIEAFHIHRFEEEAIRFLHDPSNFELVPQPQAETGYY
>NC_019693.1|WP_015147405.1|1257115_1257898_+|response-regulator-transcription-factor
MGSVCILIVEGNPHLRSLLGWHLQQVGYGVYQSADIRHAREIFYNRHPTLVILDNELPDGDGLEFCRWLYQQQETLILILSARNTESDIVEGLKSGADDYLKKPFGMQEFLARVESLVRRHRRMTPPASLDYGDLQIDLVQRRVRYQEDAIELTPQEFSLLYVLAQAGGLPMSRPELLRRAWPDAIDNPRTIDTHVLSLRKKIETDPRQPSLIQTVRNVGYRLNTEILNATPSQQPEQPMGKKTPMRQLTPVGAVPLSRG
>NC_019693.1|WP_083896848.1|1257940_1258636_-|ATP-binding-cassette-domain-containing-protein
MEKPILNEICFDVYPGDRLAIVGPSGGGKTSLLRLMARLIDPSRGALYLDGQDYRKIPVLELRQQVTLVLQDSKLLGMTVQEAIAYPLNLRGMKSPQIQERVSTWMDRLHLPTEWLERTEMQLSVGQRQLVALCRALVIEPKILLLDEPTSALDVGRAEHLLQVLAEVALHTETTLIMVNHQLDLAQQFCNRLLYLHKGTLLEDLPEEQIDSAKLRSAIVQAEAEAASEWE
>NC_019693.1|WP_044196495.1|1258795_1259335_-|hypothetical-protein
MEVREFRISPLIRVTLLSLYLALTVPLPFLSEATGAPISPGVLWVGLAMGAVAVYGALSERAIANAEGIQVTYPDWVPRGIRKGWMLPWDQVAALKPRTTGQGGLVYYFVSKSGQGYLLPMRVVGFSELVKIVEAKTGIDTRDVRPLAQPWMYFILLGLTLLLLLIDAWTIATALNLSS
>NC_019693.1|WP_015147408.1|1259505_1259946_-|DUF4079-domain-containing-protein
MDLPSFLWLWKIAAWSMGFSILAYSLLAVSGLWMYGARLGRKPQGRILVRSLHYGLGVTLVALVLLLLAVGIVGTLGHYGSLGHSVHLGVGLLVVGLVLLSAWSATQIAPGRPWARSLHITTNAILFVALAWVSWTGWIVVQKYLP

Crispr_ID: NC_019693_17

• CRISPR_ID: NC_019693_17
• CRISPR_location: 1540280-1540368
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: Cas14u_CAS-V

Consensus repeat of NC_019693_17

Consensus_repeat	Method
TATGCAATACGCCCCTAGAAGAAAC	CRISPRCasFinder

spacers of NC_019693_17

>17.1|1540305|39|NC_019693|CRISPRCasFinder
AAGGATAAGGCCCGATTCCATTGACAAATAAAGAGAATT

CRISPR arrays and Neighbor proteins around NC_019693_17

CRISPR arrays

The CRISPR arrays of NC_019693_17

>merge|NC_019693|17|1540280-1540368|CRISPRCasFinder
TATGCAATACGCCCCTAGAAGAAACAAGGATAAGGCCCGATTCCATTGACAAATAAAGAGAATTTATGCAATACGCCCCTACAAGAAAC

>NC_019693|17|17|1540280-1540368|CRISPRCasFinder
TATGCAATACGCCCCTAGAAGAAAC	AAGGATAAGGCCCGATTCCATTGACAAATAAAGAGAATT
TATGCAATACGCCCCTACAAGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015147621.1|1538273_1540067_-|translational-GTPase-TypA	unknown	unknown	gnl|CDD|224138
NC_019693.1|WP_015147614.1|1531404_1531953_+|shikimate-kinase	unknown	unknown	gnl|CDD|234654
NC_019693.1|WP_156824032.1|1535904_1536495_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147627.1|1545554_1546529_+|ribonuclease-Z	unknown	unknown	gnl|CDD|274246
NC_019693.1|WP_015147618.1|1534773_1535301_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|379646
NC_019693.1|WP_015147620.1|1536873_1538097_+|PilT/PilU-family-type-4a-pilus-ATPase	unknown	unknown	gnl|CDD|225364
NC_019693.1|WP_044196576.1|1551561_1552668_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB	Cas14u_CAS-V	-	gnl|CDD|223747
NC_019693.1|WP_015147615.1|1532068_1532965_+|acetylglutamate-kinase	unknown	unknown	gnl|CDD|239783
NC_019693.1|WP_015147629.1|1547452_1548025_-|bifunctional-adenosylcobinamide-kinase/adenosylcobinamide-phosphate-guanylyltransferase	unknown	unknown	gnl|CDD|235612
NC_019693.1|WP_015147617.1|1534216_1534642_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147624.1|1541915_1543226_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147622.1|1540479_1541460_-|putative-low-complexity-protein	unknown	unknown	gnl|CDD|224276
NC_019693.1|WP_015147626.1|1543633_1544824_-|SpoIID/LytB-domain-containing-protein	unknown	unknown	gnl|CDD|225259
NC_019693.1|WP_156823755.1|1550751_1551297_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147613.1|1529496_1531269_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|274362
NC_019693.1|WP_015147616.1|1533061_1534090_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|224561
NC_019693.1|WP_156823754.1|1528935_1529160_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147630.1|1548474_1549461_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|132997
NC_019693.1|WP_083896742.1|1549706_1550654_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|133005
NC_019693.1|WP_015147625.1|1543277_1543505_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_044196576.1|1551561_1552668_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB	Cas14u_CAS-V	-	5.7e-35	116.1	1.6

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015147621.1|1538273_1540067_-|translational-GTPase-TypA	gnl|CDD|224138	COG1217, TypA, Predicted membrane GTPase involved in stress response [Signal transduction mechanisms].	0
NC_019693.1|WP_015147614.1|1531404_1531953_+|shikimate-kinase	gnl|CDD|234654	PRK00131, aroK, shikimate kinase; Reviewed.	1.96719e-78
NC_019693.1|WP_015147618.1|1534773_1535301_+|tetratricopeptide-repeat-protein	gnl|CDD|379646	pfam14559, TPR_19, Tetratricopeptide repeat.	0.00281686
NC_019693.1|WP_015147627.1|1545554_1546529_+|ribonuclease-Z	gnl|CDD|274246	TIGR02651, Ribonuclease_Z, ribonuclease Z. Processing of the 3-prime end of tRNA precursors may be the result of endonuclease or exonuclease activity, and differs in different species. Member of this family are ribonuclease Z, a tRNA 3-prime endonuclease that processes tRNAs to prepare for addition of CCA. In species where all tRNA sequences already have the CCA tail, such as E. coli, the need for such an enzyme is unclear. Protein similar to the E. coli enzyme, matched by TIGRFAMs model TIGR02649, are designated ribonuclease BN. [Transcription, RNA processing].	1.33755e-157
NC_019693.1|WP_015147629.1|1547452_1548025_-|bifunctional-adenosylcobinamide-kinase/adenosylcobinamide-phosphate-guanylyltransferase	gnl|CDD|235612	PRK05800, cobU, adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Validated.	6.95426e-84
NC_019693.1|WP_015147620.1|1536873_1538097_+|PilT/PilU-family-type-4a-pilus-ATPase	gnl|CDD|225364	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion].	4.19783e-143
NC_019693.1|WP_015147622.1|1540479_1541460_-|putative-low-complexity-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	5.33559e-32
NC_019693.1|WP_044196576.1|1551561_1552668_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl|CDD|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.56495e-26
NC_019693.1|WP_015147615.1|1532068_1532965_+|acetylglutamate-kinase	gnl|CDD|239783	cd04250, AAK_NAGK-C, AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the non-acetylated, cyclic route of ornithine biosynthesis. In this pathway, glutamate is first N-acetylated and then phosphorylated by NAGK to give phosphoryl NAG, which is converted to NAG-ornithine. There are two variants of this pathway. In one, typified by the pathway in Thermotoga maritima and Pseudomonas aeruginosa, the acetyl group is recycled by reversible transacetylation from acetylornithine to glutamate. The phosphorylation of NAG by NAGK is feedback inhibited by arginine. In photosynthetic organisms, NAGK is the target of the nitrogen-signaling protein PII. Hexameric formation of NAGK domains appears to be essential to both arginine inhibition and NAGK-PII complex formation. NAGK-C are members of the Amino Acid Kinase Superfamily (AAK).	3.71949e-169
NC_019693.1|WP_015147626.1|1543633_1544824_-|SpoIID/LytB-domain-containing-protein	gnl|CDD|225259	COG2385, SpoIID, Sporulation protein and related proteins [Cell division and chromosome partitioning].	1.48338e-102
NC_019693.1|WP_015147613.1|1529496_1531269_+|PAS-domain-S-box-protein	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	3.21191e-57
NC_019693.1|WP_015147616.1|1533061_1534090_+|alpha/beta-fold-hydrolase	gnl|CDD|224561	COG1647, COG1647, Esterase/lipase [General function prediction only].	3.03198e-12
NC_019693.1|WP_015147630.1|1548474_1549461_+|glycosyltransferase-family-2-protein	gnl|CDD|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	3.73404e-35
NC_019693.1|WP_083896742.1|1549706_1550654_+|glycosyltransferase-family-2-protein	gnl|CDD|133005	cd02511, Beta4Glucosyltransferase, UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide. UDP-glucose: lipooligosaccharide (LOS) beta-1-4-glucosyltransferase catalyzes the addition of the first residue, glucose, of the lacto-N-neotetrase structure to HepI of the LOS inner core. LOS is the major constituent of the outer leaflet of the outer membrane of gram-positive bacteria. It consists of a short oligosaccharide chain of variable composition (alpha chain) attached to a branched inner core which is lined in turn to lipid A. Beta 1,4 glucosyltransferase is required to attach the alpha chain to the inner core.	1.2207e-77

Protein sequences

>NC_019693.1|WP_015147621.1|1538273_1540067_-|translational-GTPase-TypA
MSLPIRNLAIIAHVDHGKTTLVDALLKQSGIFREGEEVPDCVMDSNDLERERGITILSKNTAVRYKETLINIVDTPGHADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKGLRPIVVVNKIDRPRADPHSAVDKVLDLFIELGADDDQCEFPYLFASGLSGYAKTKMEDEGVDMQPLFDLILDRVPPPVGDPTKPLQLQVTTLDYSEYVGRIVIGRIHNGVIKAGQQAALVKEGGEIVKSKISKLMGFEGLNRVDMAEASAGYIVAVAGFADANIGETITCPNEPLALPLIKVDEPTLQMTFWVNDSPFAGQEGSFVTSRQLRDRLLRELETNVALRVEETDSPDKFLVSGRGELHLGILIETMRREGYEFQVSQPQVIYREINGQPCEPFECLVLDVPEEGVGGCMQRLGERRGEMQDMHVNATGRTQLEFAIPARGLIGFRGEFMRLTRGAGIMNHSFLDYRPLAGDIEARRNGVIIAFEEGTATFYSLKNAEDRGVFFITPGTKVYKGMIVGEHNRPQDLDLNVAKTKQLSNVRSSTGDELVQLQAPVEMSLERALEYIGPEELLEVTPVSIRLRKMSIKKLAKR
>NC_019693.1|WP_015147620.1|1536873_1538097_+|PilT/PilU-family-type-4a-pilus-ATPase
MSITNSAIKRQKSSGPPRVLPPPPPPPSGMANRKAAEPAQTQTHYIKALVEQAHSSKASDIHIRVGEIPRFRIRGQMREALEQERLTPEKFNAYLNEILTPSQRSQFAKTKELDTAIFYPGFIRCRVNCFETLMGGAMVLRLIDLHVPSLDELRLPEVLKKVISHSQGLILVTGPTGSGKSTTMAAMIRCLNESSYKHVISIEDPIEYVHASKSCLISQREVGLHTDDFHSSLRSALREDPDVILIGEMRDRITINIALQAAQTGHLVLGTLHTRTAISAINRLLNMFNPEEQSAIRIQIVETLYAVIAQLLLPTTDGGRTTINDVLINTATMQDYLYKGDDDGAFALMHSDTYEGMQVMNQDLYRKVMEGRVAIEVAEMHSPDPGELDRLIRTGGFDASRSPRDFA
>NC_019693.1|WP_156824032.1|1535904_1536495_+|hypothetical-protein
MSPEQQHQALNDLIQSELVSLAEKTQTYLHDRIHAVLKYFDVDETGESKRIAEYYYRYYLLTGTVPENLTAEYLTHLLNFIIGIEVLKIIFMMSFIEQQRFFEIQGRYAIQVMIFYRYIKPIRDKLIHEKLIIRDVAGSFYYTKINLSEERILDYIFEAFKLEKIETLGELAKDLQFDREYIYKPPHADDRDVPVF
>NC_019693.1|WP_015147618.1|1534773_1535301_+|tetratricopeptide-repeat-protein
MSTEPLEQFKIEYQTGKDAFERGQYREAVQFLAKASQLLDRNSRLGGETLMWLVTAYQAAGQSSEATALCRTLLRHPSIETRKQAKRLIYILEAPELKSRPEWLVSIPDLSILDEGNSKIAQVSMTTTAKKPKPQSPESELPFEDLDQINTQDNGFVWVAMVAIGLLVAVLLGFS
>NC_019693.1|WP_015147617.1|1534216_1534642_-|hypothetical-protein
MFEKFRSFRAFHPVAIALTPMAIAAGVFQFSTPAAHANLSIVIDRGISIQVGQPRTVHYGHPGVYPGQYNPYSPPNYYPQYHPRRGQPTIRNSTLINPTVIDSRIENSTLINPVIIDSQNRNRTLVQPRTNQIRGVLPGSL
>NC_019693.1|WP_015147616.1|1533061_1534090_+|alpha/beta-fold-hydrolase
MLNYCGSIADFVCHAKSREDALPLLNEHCRSRFFLHPRRTKKVLLFFHGFTAAPWQFVPMGEAFFKAGYNVLVPLMPGHGHGGNWSRQNPAPLPTTAALYHDFAQEWLDRAQELGEEVYIGGLSGGGTVAAWLALERCNDIAGCLLFAPYLSSSSRVLDLFVRKLTPDYCDWGAPRPGQIRYGYDGFEVEALKTVLLMGGEVLNRAKREASAPMFIISSESDRAVGHREHRTLFESVYRFTPRSWYHIFDRVLDIPHTMMTQGEGNPHESMLIAMAKAYIDSDLTWDEIGDIAERMTRGETFDAAVRTLNLGDRAAAEMPIFMTLLDKRSLVMQRNPRFSRA
>NC_019693.1|WP_015147615.1|1532068_1532965_+|acetylglutamate-kinase
MLTEKELSQQETEAMRVKVLSEALPYIQQFAGRTIVVKYGGAAMKDSTLKDQVMRDLVFLACVGVRPVLVHGGGPEINSWLDKLAIEPQFKNGLRVTDAPTMDVVEMVLVGRVNKEIVALINQAGGSAVGLCGKDGNLITARPQGDEGIGFVGEVSSVNTKILEALVKSGYIPVVSSVAADETGQSYNINADTVAGELAAALGAEKLILMTDTAGILQDPTDPSTLLTQLDIQQARELMKSGVVSGGMIPKVTCCVRSLAQGVKAAHIIDGRINHSLLLEILTDTGIGSMIVASGYQQ
>NC_019693.1|WP_015147614.1|1531404_1531953_+|shikimate-kinase
MKQFLKGCNLYLIGMMGSGKTTVAQILAPQLEYRYLDSDRLIEQVAGQSIPEIFAESGEAAFRELETKVLSELCAYTHLVVATGGGIILNRQNWSYLQHGVVVWLDVPVEQLYQRLAGDTTRPLLRDPDPMAKLRSLLDQRQSLYKQADVRVIVGPEDTPEQIATGVLAEISKILKDHTNQN
>NC_019693.1|WP_015147613.1|1529496_1531269_+|PAS-domain-S-box-protein
MVFASKTRNRALLKAIPDAIFWIHKDGTCLDYQPPENFTLWAGCRSPGQRLQPEGIDNFSDRTYIGQKWWEIWPLEVIQQSREFLERAIATGSEERFEVELLGKDSLCSVQFFPLISMISHPYLPSFYEIKIIPSSEDEFLVILRDLTQVKQAESQRRHDLEQKALQLHQTVLALEAEKAHRQQIEEILAFTQFSLNRAGDAVFWVNSDAQFFYVNEAACLSLGYSREELILMTVHDINLDLPKNVWSDYWDEIKQHGSFTIECHHRTKEGRKFPVESTVNYLEFNGKEYNCILARDITDRKQVEAQLLETKAAAEAANRAKSTFLANMSHELRTPLNAIIGYSELLQEDARDIGITEPEFLDDLRSINTAGKHLLALIGDILDYSKIESGKMQLFLESFNLDKAIAQICHTAQPLIEKNSNQLVVQFSGELGSMHADLTKMRQILFNLLSNAAKFTRQGKIEVAVTQQPRNAIPLAFSPEQEWDPNDLFVVFQICDTGIGMTQDQLNNLFQAFMQADASTTREYGGTGLGLAISRLFSQMMGGDIVVDSQLGVGSTFTVYLPMEVKLPEPHEPDWQEPSVPTVAIGQES
>NC_019693.1|WP_156823754.1|1528935_1529160_+|hypothetical-protein
MGFFLGDRTSRGKSFHTGAIASLCFHTGAIASHECVTWRSPPGGPHPNPPQDTGEGTGSVKTHLPHPHRCDRLS
>NC_019693.1|WP_015147622.1|1540479_1541460_-|putative-low-complexity-protein
MKRTIAPKQFAATLLSAAAAALLPFAFPRTAFGVDPDHVLQLFRTNECMGCDLIGADLRGANLVGANLLGADLRGANLTESNLSRADLRGAILRWADFSGANLSEARFVRPLPTTIRRDRITSVNPPLVISQLTAADLRDAIMNGTNLHKANLSGANLVRADLRNANLTQADLSQANVRAANLSGANLRGARLLSSRFNGTDLSFADLSFTELSGAHLMDANLQQASLRGANLSAIEPTGPQCPGAQCRTLITHLDGANLSQADLRGANFTGASLERATLQNANLYGANLTRARLGEANLENVDLFNANLNDAQLSLTSQPDRGRR
>NC_019693.1|WP_015147624.1|1541915_1543226_+|hypothetical-protein
MALNPTVMQTVEKLDYRVTVGDVATSAGLQVNLAERELLALASEAGGHLQVADTGDIVYQFPKQFRAILRNKYFRIQLQEWWEKVWRILFYLIRISFGIILILSIFIIFASIFILLTMANKDSSSNRSRSRGGGMIFFPRMFWGPDIFWFFNPNYGRYQRQRRQKAQASSSSEESMNFLESVFSFLFGDGNPNANLEERRWQAIAATIRNNQGAVVAEQIAPYLDDLGTGYSNEYEDYMLPVLTRFNGRPEVSPDGQIVYHFPELQTTVQQRNTLAVPAYLRELPWKFSEASSNQLSLAAGLGVLNIGGGIFLGYLLQDGAIAAQIGGLVAFAASIYWLLIGYGVAFLSVPLIRYLWLKGRNRKVEARNEARQQQAIGLNQPSDELRQKLAYAQQFAAQNIIESGDIAYTTETDLIEQESQNTAKLDAEWRKRLEG
>NC_019693.1|WP_015147625.1|1543277_1543505_-|hypothetical-protein
MPKWEYLFVRFDYFAGDLCVHSANGQELREEQKKQPLYKYSNQMGEEGWEMVNFNFTPAYGYGFLTFKRLKQEEG
>NC_019693.1|WP_015147626.1|1543633_1544824_-|SpoIID/LytB-domain-containing-protein
MKLTPTPTRLLSPLKPLWESRRQWWLVALIWLMMVAPAQASLLLRVAIKQNVSEVTIGSSTPATVKDSAGRSLGQLEGMQASLARSTGSGVAVGGWQGNQIAIEPSGDGFVYIGDRWYRGNTVLVPTSSGLTVINQVDMEEYLYSVLGAEMSPSWPQEALKAQAVAARTYALYQRQKRGNSLYDLGNDTYWQVYQGVEKEANTTHDAVQATAGQVLVYNDQPIEAVFHSSSGGHTENVEDVWMDPRPYLRGVPDHDAGSPVYQWTETFTSSQLSSRISGVGNVLSMKPQRTTPHGRIQSMLIVGDAGQRTIDGEELRQALNLRSARFTVMPQHGPSASKNTVSNIPAGFTIQGRGFGHGIGLSQWGAYNLAAQGVNYQQIVLHYYQNANLAKIRVE
>NC_019693.1|WP_015147627.1|1545554_1546529_+|ribonuclease-Z
MQITFLGTSSGVPTRSRNVSSLAVRLPQRSEVWLFDCGEGTQHQILSSDIKISQISRIFITHLHGDHIFGLMGLLASCGLAGNASRIDIYGPAGLNDYLAACSRYSQTHFSYPIKVHQSRPGVVYEDDEFIVKCGRLEHRVTAYGYRVEEKDRPGRFNVEKAAALGIPSGPLYGQLKRGETVTLSDGRQISGQELCGPTEPGRKMAYCTDTIFCEGAVQLAQDVDVLIHEATFSHQDAQLAIDRLHSTSTMAAQVALAAGVKHLIMTHFSPRYAPGNDIQLEDLRQEAQAIFPNTEMAYDFWTYEVERHRSTELESVGTRSDRP
>NC_019693.1|WP_015147629.1|1547452_1548025_-|bifunctional-adenosylcobinamide-kinase/adenosylcobinamide-phosphate-guanylyltransferase
MVKRIILVTGPARSGKSEWAELLAQQSGKPVIYLATSRLDPDDPEWQGRIDRHRQRRLASWRTQEVPVALTAAILQGTTSDNPACLLVDSLGTWVANLLAEEDPTWRAILEELMETIKGLKQGTVIFVAEETGWGVVPAYPMGRTFRDRLGDLVRRLGAIADPVYLVTGGHAVNLSAIGSVLPPSKTLED
>NC_019693.1|WP_015147630.1|1548474_1549461_+|glycosyltransferase-family-2-protein
MPQPDISAIICTHNRDVYLGDAIDSLLQQDFPNFEILVVDNGSSDRTQEVVAQRESDSRVKYIYEPTLGLSFARNTGFQQARSEILAYLDDDAVASPQWLRTLWNAYQQNENLAIAGGKVTLIWPEGVEPPVWLSAGLAENLGAYDLGDQQILIREPGLTPRGLNYSIRRSFLEKVGGFDLNLGRVGKSLLSNEELHMTELALNQGWEVAYLPEAIAAHNVAPERLKRSWFLSRGWWQGISECYREQLMGRAGMGQLSNGGEKVLRGVYKSLKYVGDPALSFDNLVYAYGQIGYLSAAIRSLFLGSPATGSTTTSGREKYSGDRAEPG
>NC_019693.1|WP_083896742.1|1549706_1550654_+|glycosyltransferase-family-2-protein
MASTASKIPISVLIPAKNEEANLPACLASLEPADEVFLVDSQSSDRSIEIAENWGAKVVQFHFKGGWPKKKNWSLENLPFRNEWVLIVDCDERIPLELWEEMAQAIQNPNCDGYYLNRKVFFLGKWIRFGGKYPDWNLRLFRHQKGRYENLNTEDVPNTGDNEVHEHVILDRPAAYLKADMIHEDFRDIYQWLERHNRYSNWEARVYYNLLSGKDDSGTIGANFFGDAVQRKRFLKTVWVRLPFKPLLRFIWFYIIKLGFLDGKAGYIYGRLLSQYEYQIGVKLFELRQFGGQLNQLSAKPTAESPTLPEIKESA
>NC_019693.1|WP_156823755.1|1550751_1551297_-|hypothetical-protein
MAKTVLACWLSLQRTEVRLNAGEELALENIIQQLHQHGEAWESLQRDLIRLIQENPSLNRVFQGIKPELDKIETEELRELFIKESEVSQANLASSPVGTFDVATANNPVTHSEAMAELLVQLATQMQRQIADPTLATPGNFQKSKEPEEVDDEAFALACALVDEYELGWNREWQQIAITTS
>NC_019693.1|WP_044196576.1|1551561_1552668_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MYPEKKLHQLWKQWLAAYRWIYNWTIAYLRHEPHLSAFSLQSLARQSNRPDWVKELPGHQLQEAVADAVDAHKQAKANQGTASFKSCRAFSQVIKFKAGNFKNGTWYCQRTKGLEFKSAEEFPQQCPYGTQILYQKGKWFGCFPEYREPTPTQEERVIALDPGVRTFLTGYDGETILEIGQKDIGRINRLCTHLDQLMSKIALSSNKRQRYKMRKAATRMRCKIQNLVKDLHNKSASFLVNNYKLILLPTFETSQMVERHKRKIRSRTARNMLTWSHYKFAKHLEQKAARNGVMVVRCNESFTSKTCPECGHIHEKLGGNKTFRCPECGYEAPRDWNGARNILLRALQATAFTIVGDAILFLELLSHE

Crispr_ID: NC_019693_18

• CRISPR_ID: NC_019693_18
• CRISPR_location: 1637486-1637599
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_18

Consensus_repeat	Method
AATCTCTCGCCATGAGCCATCAATCCAGG	CRISPRCasFinder

spacers of NC_019693_18

>18.1|1637515|56|NC_019693|CRISPRCasFinder
CGAGAAACCCGGTTTCTGCTCCAGGGTAGGGGTTGAGAAACCGGGTTTCTTCACCC

CRISPR arrays and Neighbor proteins around NC_019693_18

CRISPR arrays

The CRISPR arrays of NC_019693_18

>merge|NC_019693|18|1637486-1637599|CRISPRCasFinder
AATCTCTCGCCATGAGCCATCAATCCAGGCGAGAAACCCGGTTTCTGCTCCAGGGTAGGGGTTGAGAAACCGGGTTTCTTCACCCAATCTCTCGCCATGAGCCATCAATCCAGG

>NC_019693|18|18|1637486-1637599|CRISPRCasFinder
AATCTCTCGCCATGAGCCATCAATCCAGG	CGAGAAACCCGGTTTCTGCTCCAGGGTAGGGGTTGAGAAACCGGGTTTCTTCACCC
AATCTCTCGCCATGAGCCATCAATCCAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015147696.1|1634886_1636329_+|DASS-family-sodium-coupled-anion-symporter	unknown	unknown	gnl|CDD|273267
NC_019693.1|WP_015147698.1|1636905_1637442_+|adenylyl-sulfate-kinase	unknown	unknown	gnl|CDD|179157
NC_019693.1|WP_156824033.1|1647461_1648898_+|response-regulator	unknown	unknown	gnl|CDD|381117
NC_019693.1|WP_015147693.1|1630493_1631114_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147694.1|1632617_1632830_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_052315698.1|1629110_1629749_+|hypothetical-protein	unknown	unknown	gnl|CDD|238535
NC_019693.1|WP_015147692.1|1630059_1630497_+|DUF4065-domain-containing-protein	unknown	unknown	gnl|CDD|226128
NC_019693.1|WP_156823758.1|1629511_1630021_+|hypothetical-protein	unknown	unknown	gnl|CDD|273267
NC_019693.1|WP_015147699.1|1637691_1638153_+|chemotaxis-signal-transduction-protein	unknown	unknown	gnl|CDD|223905
NC_019693.1|WP_015147701.1|1639548_1641300_+|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl|CDD|223910
NC_019693.1|WP_015147704.1|1645605_1646616_+|chemotaxis-response-regulator-protein-glutamate-methylesterase	unknown	unknown	gnl|CDD|237135
NC_019693.1|WP_015147708.1|1653386_1653614_-|ferredoxin-family-protein	unknown	unknown	gnl|CDD|224069
NC_019693.1|WP_015147707.1|1652057_1653329_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_019693.1|WP_044196590.1|1642913_1645280_+|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl|CDD|223716
NC_019693.1|WP_156823759.1|1631241_1631436_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147700.1|1638155_1639478_+|methylase-of-chemotaxis-methyl-accepting-protein	unknown	unknown	gnl|CDD|224271
NC_019693.1|WP_015147706.1|1649926_1651789_+|biosynthetic-type-acetolactate-synthase-large-subunit	unknown	unknown	gnl|CDD|236014
NC_019693.1|WP_015147697.1|1636330_1636762_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147695.1|1633054_1634389_-|DUF2254-domain-containing-protein	unknown	unknown	gnl|CDD|378351
NC_019693.1|WP_015147702.1|1642158_1642881_+|chemotaxis-signal-transduction-protein	unknown	unknown	gnl|CDD|223905

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015147698.1|1636905_1637442_+|adenylyl-sulfate-kinase	gnl|CDD|179157	PRK00889, PRK00889, adenylylsulfate kinase; Provisional.	1.57961e-118
NC_019693.1|WP_156824033.1|1647461_1648898_+|response-regulator	gnl|CDD|381117	cd17575, REC_WspR-like, phosphoacceptor receiver (REC) domain of WspR response regulator and similar proteins. The GGDEF response regulator WspR is part of the Wsp system that is homologous to chemotaxis systems and also includes the membrane-bound receptor protein WspA. In response to growth on surfaces, WspR is phosphorylated by the Wsp signal transduction complex and is activated, functioning as a diguanylate cyclase (DGC) that catalyzes c-di-GMP synthesis. WspR is a hybrid response regulator-diguanylate cyclase, containing an N-terminal REC domain and a C-terminal GGDEF domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.06245e-73
NC_019693.1|WP_052315698.1|1629110_1629749_+|hypothetical-protein	gnl|CDD|238535	cd01115, SLC13_permease, Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.	2.95116e-19
NC_019693.1|WP_015147696.1|1634886_1636329_+|DASS-family-sodium-coupled-anion-symporter	gnl|CDD|273267	TIGR00785, Uncharacterized_transporter_HI_0020, anion transporter. The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds].	5.58191e-62
NC_019693.1|WP_156823758.1|1629511_1630021_+|hypothetical-protein	gnl|CDD|273267	TIGR00785, Uncharacterized_transporter_HI_0020, anion transporter. The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds].	9.52873e-09
NC_019693.1|WP_015147699.1|1637691_1638153_+|chemotaxis-signal-transduction-protein	gnl|CDD|223905	COG0835, CheW, Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms].	2.92642e-22
NC_019693.1|WP_015147701.1|1639548_1641300_+|methyl-accepting-chemotaxis-protein	gnl|CDD|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	4.38636e-55
NC_019693.1|WP_015147704.1|1645605_1646616_+|chemotaxis-response-regulator-protein-glutamate-methylesterase	gnl|CDD|237135	PRK12555, PRK12555, chemotaxis-specific protein-glutamate methyltransferase CheB.	5.62758e-168
NC_019693.1|WP_015147708.1|1653386_1653614_-|ferredoxin-family-protein	gnl|CDD|224069	COG1146, COG1146, Ferredoxin [Energy production and conversion].	1.54018e-10
NC_019693.1|WP_015147707.1|1652057_1653329_-|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	3.24031e-22
NC_019693.1|WP_044196590.1|1642913_1645280_+|hybrid-sensor-histidine-kinase/response-regulator	gnl|CDD|223716	COG0643, CheA, Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms].	3.48854e-150
NC_019693.1|WP_015147700.1|1638155_1639478_+|methylase-of-chemotaxis-methyl-accepting-protein	gnl|CDD|224271	COG1352, CheR, Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms].	6.72085e-64
NC_019693.1|WP_015147706.1|1649926_1651789_+|biosynthetic-type-acetolactate-synthase-large-subunit	gnl|CDD|236014	PRK07418, PRK07418, acetolactate synthase large subunit.	0
NC_019693.1|WP_015147692.1|1630059_1630497_+|DUF4065-domain-containing-protein	gnl|CDD|226128	COG3600, GepA, Uncharacterized phage-associated protein [Function unknown].	1.2289e-19
NC_019693.1|WP_015147695.1|1633054_1634389_-|DUF2254-domain-containing-protein	gnl|CDD|378351	pfam10011, DUF2254, Predicted membrane protein (DUF2254). Members of this family of bacterial proteins comprises various hypothetical and putative membrane proteins. Their exact function, has not, as yet, been defined.	9.17881e-169
NC_019693.1|WP_015147702.1|1642158_1642881_+|chemotaxis-signal-transduction-protein	gnl|CDD|223905	COG0835, CheW, Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms].	3.78759e-21

Protein sequences

>NC_019693.1|WP_015147698.1|1636905_1637442_+|adenylyl-sulfate-kinase
MQQRGVTVWFTGLSGAGKTTISQGVEKELRSLGYQLEVLDGDIVRQNLTKGLGFSKEDRDENIRRIGFVSHLLTRNGVIVLVSAIAPYREIREEVRHRIGDFVQVYVNAPLEVCEERDVKGLYKKARAGEIKNFTGIDDPYEAPLNPDIECSTKDESEAESIAKVLQYLKDKGYITQV
>NC_019693.1|WP_015147697.1|1636330_1636762_+|hypothetical-protein
MAEILLVLTNPYGYEKALHLAFEEAKQADSLFRVTFIIDPEALDDLMRDLGENGWLGIGSRRSLQISMMEGYRALATDILEEVTRRAVSLGIAVKTEVNEEGIRSYLSGLGTPGPEKIFVSGSHALGPLIQTLDCPLEWLPED
>NC_019693.1|WP_015147696.1|1634886_1636329_+|DASS-family-sodium-coupled-anion-symporter
MGLKQYFGFISERFSALLQRSQLFQHRWIGYIIAVAIYLTLFLIPLPGFEPSAQRAFAVFGLAAFSWGTTLLPLPVTAIIILFLLPFSGAISAQETYAYFGNRAVFFILGAFILASPIMRSGLSTRIALAVVTRFGNSQRQILGSILGLSALMSCFISAHAVAAMLFPIVLEVVRAAGAKPGKGFGVAAFLSLAWGVVIGSNTTLLGGARGPLALGILQNTTGQTISFAQWTLFVAPVVLVLLPVAFFVLQGVGQTEEVSLSTARRFLEKRNQQLGEISRREIVTAGILLLTILLWMTLGDRWGLDVIALLGVILTFILGVANWGEVEEDVNWGIFIMYGSAIALSAALNDTGAASALTQLLLGFGIESPLLIFAAVTIIALAMTEFMSNSAAVAVILPVALALAEKYGIEPRAMTLGVVIPAGLGFMLPVSTPALAIAVSSGYVRPLAVLRWGVWLDIISIVVFLGLSQFYWPLVGLRG
>NC_019693.1|WP_015147695.1|1633054_1634389_-|DUF2254-domain-containing-protein
MKYAKLAKLWDSLHSSFWFVPTLMVLLAIALSFITIGIDYSQEVNIVERIDWAYSLGPNGSRAILSAIAGSMVTVATTAFSITIVALQLASSQFGPRLLRNFMQDTGNQIVLGTFISTFVYSLMVLRTINGVEKDEFVPHLAVTIGLGLAIASVGVLIYFIHHSASSIQVDQIIKQVGYDLDVAIDRLFPERIGRNTSKHLEEESLAAIPADFDRVACPIKTIASGYIQTINDKQLMQIATENNLLLRIQQRPGRFVVKGSEIVRVFPEEKVNKKLAVQINEAFILGSQRTEQQDVEFPIDQLVEIAVRALSPGINDPFTAIRCIDQLSAALCHLAQREIPSPYRYDDHNQLRIIAEPISFADATDTAFNQIRQYGKSSVAVTMRLLEAIAAIAPFTHRIPDRTTLQRHADMIERGSQEGIAEELDYKNVKERYLAAVKAIGQV
>NC_019693.1|WP_015147694.1|1632617_1632830_-|hypothetical-protein
MAKKIKGNQDGEGGRNDSYTIPGRGIVQREELVKEVEKGKHPDFSIYERDQEKFVRANPDSSQTNNVNRD
>NC_019693.1|WP_156823759.1|1631241_1631436_+|hypothetical-protein
MLDCLLEITTHRNSDRHFPLHLSKAIAFSNLIPTKSDRINLIKATRSHYYRRPAIVSCSAFKLG
>NC_019693.1|WP_015147693.1|1630493_1631114_+|hypothetical-protein
MTDKPSKAEKRRQRQEEKAQAHKAKSVKFSSSVENLATKTVKIAPIPKLALKVVKVQENPSRNKFVYLPNEEAFSNACHLTWCTTISDLEGEWSWQEQRCWTEEEWQTQILPNLSSLEKSTWSEILFEQKTPAKGGKSVPKHHSQELITLVKEAQNRWIEIGLEEYDTAFRFRFANTVRAWGVRLEGHFYLVWWERHHKIYPVPQP
>NC_019693.1|WP_015147692.1|1630059_1630497_+|DUF4065-domain-containing-protein
MARAVDVAKYILTKTGEMTAMKLQKLVYYSQAWSLVWDEDPLFEEDIQAWANGPVVQVLYSYHRGQFKVNEDTFAADGNVDALTPNQKDSIDKVLEALQDKSGQWLSELTHRESPWKDARGDLKPTERGDNVITLAAMHEYYSSL
>NC_019693.1|WP_156823758.1|1629511_1630021_+|hypothetical-protein
MWQQPAPDSRGHSRTLRPNVLFYQCSCRGSHVISHRPRGSAGLWSQTGQRLWGRRLFIPRLGSGDWLKYHPPGGARGPLALGILQNTTGQTISFAQWTLFVAPVLLVLLPLAFFVLQGVGQTEQVSLATARRFLEKRNQQLGQISRREIITAAIIVDAIATKAQCSCVL
>NC_019693.1|WP_052315698.1|1629110_1629749_+|hypothetical-protein
MGLKQYFGFISERFSALLQRSQLFQHRWIGYLIALAIYVTLLLIPLPGFEPSAQRAFAVFGLAAFSWGTTLLPLPVTAIVILFLLPFSGAISAQETYAYFGNRAVFFILGAFILASPIMRSGLSTRIALAVVTRCGNSQRQILGAILGLSALMSCFISAHAVAAMLFPIVLEVVRASGAKPGKGFGVAAFLSLAWGVVIGSNTTLLGGRGDL
>NC_019693.1|WP_015147699.1|1637691_1638153_+|chemotaxis-signal-transduction-protein
MLMLLFYVGPDRYALGCSQVVEVIPLVELRKLYHAPEYMAGLFNYRGSIVPVLDLCHLIQGNCSRHCLSTRIILVNYQQTNQNSRLIGLMAERVTDTVDILESEFKDEGIHLENAAYLGKILMDEKGTIQELCLESLLSEQAQAFLLPIGETE
>NC_019693.1|WP_015147700.1|1638155_1639478_+|methylase-of-chemotaxis-methyl-accepting-protein
MVWNAIEQKLRKTIGLDPKTLGSQAIAKAVRYRMEVCGVENVATYLDIWLCSPQELQALIEETVVPETWFFREPESFEFLRRYVLFDWLPTHPEAILRLLSVPCSTGEEPYSLAMTLLDAGLPPSSFVIDAVDISQKAQIKAEQGLYREHSFRGNQLGFRHRYFQKTPHGYQLSAAVKETVNFIHGNLLEPLFLYGKPLYDIIFFRHLLIYLESDARDRALQVLNRLLSPTGVLLVGSAEAGPLIEKRFISLRHSMTFAYRKRQKSDGTARFFVPPNDPEHSTLSGLQRSPPRTPSRFKPPSQPDPSPAQAPEARSEHPHQSWAIAPTAPSPPKRIPQSPLIQARHLADLGRLNEAAQLCETYISQHRTDANAYVLLGEILQGAGHYERAGQCWEKAIYLEPHHYEALMHLLLLKESHGDLTNACALRQRIQRLLKSQGE
>NC_019693.1|WP_015147701.1|1639548_1641300_+|methyl-accepting-chemotaxis-protein
MFRNLSLQARMLAAFIFMGLIVLSVALVGWGGNYRLSNRLSSITSNAMPSTSALWKIKEGQTQIQSAERLLLNPRSSNERRIVAKERINRAWQQINQAFAQYNNIVGKDLEETRLYNQFMEAWNQWKQIHEQFLQLNQEFEAANILQPWETQVQLWEAGQSNSPQMASARAAAALLERMNDQRTRRNIPAYQGAEETLQEVVEYNQNEASQVVRDAEQDVAESSFWVVLGMLLGPLTALIFGFYFSTTIAKPLGAKIVGVVRVAEKISSGDLTTAVTVTETQDEIGRLTAAFAQMTQKLNSLIRQVQHSGIQITSSTTEIAASGKQLEATVTEQVASTNEVVATAKEIAATSGELVKTMDQVGELAGQTAIAAGTGQQEIVRMESTMRQLANATASISAKLGVISEKANNINSVVTTITKVADQTNLLSLNAAIEAEKAGEYGTGFAVVAREIRRLADQTAIATLDIETMVKDMQSAVSTGVMEMDKFTTEVSRGVEDVRTISGQIGKIIERVQSLTPRFDAVTKGMEDQSEGAQQISDAMVQLSEASRQTAQSLRDTNRAIEQLNEAAQGLQREISFFKVQM
>NC_019693.1|WP_015147702.1|1642158_1642881_+|chemotaxis-signal-transduction-protein
MTEKCWNQIGIQGDRSCSELNTVIHCRNCPIYTRAGRNLLERDAPENYRAEWTDLLAQTPTTLGGDRNALPQLQRATAEFFDPISLVIFRLGVEWLALAASTFQEITQPCTLHTLPHRTNEILLGLVNIRGELLPYISLSNLLGLERQGTHPKPLNPQGDLTRTVYSRMVVVNIQGDIWVFSVDEIEGIHRCDRHLIEEVPAVVSKAPITYTKWIVNWQDKKVNYLDEEFVFSSLKRRIL
>NC_019693.1|WP_044196590.1|1642913_1645280_+|hybrid-sensor-histidine-kinase/response-regulator
MLDLFAMEVETQAALLNENLLGLEHHSQSGKELEALMRGAHSIKGAARIVQLNEAVHIAHVMEDYFVGVQEGQIRVSEDHIDILLAGVDLLLSMGQVKEPELKAWMQEHQPEIDLIASQIKNIASPGTLLEDPPQAHPEPQTRGDRPAIPPPTPEPEANPPEPPPKPESDLTPVESPPSPNLVPFPEPEPPEPMRAQSPSSSSSRGDRVVRLSADNLNRLMGLAGESLIEANWLQPFADSLLKLKKQQTQLSKTLEKLEGSLSENGTAQNTKDYLETAQTQEKECLELLNNRINELELFARRFANLSDRLYREVIDSHMRPFSEGVSGFPRMMRDLAKQLGKSVKFEIMGKATKVDRDILDKLESPLTQILRNAIAHGIESPSERIEKGKPAEGTVRLEAVHRGGMLLITISDDGRGINLAEVREQVIANQLVNPEFAHQLTEAELMEFLFLPSFSTVTEVTELSGRGFGLDIAKGMMQEVGGLLRAQSELGKGTRFHLQLPLTLSVIRTLLVEISSEPYGFPLTRIDRIVQIQRGDIFVVENRQYFTLNGQNISLVSAHQVLELEQSELNDDLLSVIVLSDRTNYYGLVVDRFLGERDLVVRPLDPRLGKVRDISAAALMEDGSPVLIIDVEDLVRSLDLLLSSGRLSQITQDSQVKESKRHQKILVVDDSITVREMERKLLQNRGYKVEVAVNGVDAWNAARTGDYDLIITDVDMPRMNGIELVNHLKSHVKLKSTPVIIVSYKDREEDRLLGLEAGANYYLTKSSFHDDTFLNAVIDMIGTPDEI
>NC_019693.1|WP_015147704.1|1645605_1646616_+|chemotaxis-response-regulator-protein-glutamate-methylesterase
MKIAIVNDMLLAIEALRRVLTSVPDYELLWVARNGAEALNKCAVVRPDLILMDVFMPVMDGVEATRQIMRDCPCAILLVTSSINTHLPKVFEALGYGALDVVITPILGYYGTAEGGETLLEKIRTIHKLLGKPLSKKPKNLIPVKSCYRNQPYPPLVAIGASTGGPTAIAKILSQLPQDFRISVAIVQHIDVQFSASFVQWLSQQTRLKVELAEVGMTPQPGKIIVAGTNDHLFMRPDRTLGYTKHPLNNPYRPSVDVFFTSLAENWPGQGLGVLLTGMGRDGAVGLSVLRGAGWQTIAQDANSCIVYGMPKAAVELGAVQQSLTPEAIGIKLLSL
>NC_019693.1|WP_156824033.1|1647461_1648898_+|response-regulator
MMKELSAQPVSILLIDDQPIVSEAIRRMLATETDIKFYSCTDPDQAIQIATQIQPTVILQDLVMGEIDGLMLLRFFRANPATRDIPIVVLSTKEEPEQKAQAFASGANDYLIKIPDKIELIARIRYHSNAYHNLCKRYEVELTNKYNQELELRVQERTQELTEALENLKQTQAQLVQSEKMSGLGQLVAGIAHEINNPISFISGNLIHFIEYAEGLLTLVELYDQAFPDLPISIQDFRESLDLEFVREDLPRLISSIRGGADRIREIVVNLRNFSRMDESERKQADLHEGIDSTLVMLQHRLEESQIELIKEYGELPSIECYPGQLNQVFINILTNAIDALSDRPEPSPVETVPRKISIKTELQGEGVAIRITDNGIGIPPELQTQIFNPFFTTKEVGQGTGLGLAISYEIIVKKHHGQIRCQSHPSHGTEFTIEIPLGHNKRGNLAEMPLAQRVCPLPSASKIPPTELAAMQWLEVG
>NC_019693.1|WP_015147706.1|1649926_1651789_+|biosynthetic-type-acetolactate-synthase-large-subunit
MLSESRSDRKTKPVVVPTRRTGAYALMDSLKRHGVKHIFGYPGGAILPIYDELYRFEATGDVQHILVRHEQGASHAADGYARATGKVGVCFGTSGPGATNLVTGIATAHMDSIPMVIITGQVPRAAIGTDAFQETDIYGITLPIVKHSYVVRDPRDMARIVAEGFHIASTGRPGPVLIDVPKDVGLEEFDYVPVEPGSIKLPGYRPTVKGNPRQINQAIELIRQAKKPLLYVGGGAIAASAHHEIKELAEHFQIPVTTTLMGIGAFEEHHPLSLGMLGMHGTAYANFAVSECDLLIAVGARFDDRVTGKLDEFAARAKVIHIDIDPAEVGKNRGPEVPIVGDVQQVLMDLLRRLRETGDLADVNQTKEWLGRIERWREDYPLLVPYPENALSPQEAIVEVGRQAPDAYYTTDVGQHQMWAAQFLKNGPRRWISSAGLGTMGFGVPAAMGSQVALPDHQTICISGDASFQMNLQELGTIAQYGIKVKIVIINNGWQGMVRQWQETFYGERYSSSNMEIGMPDIPLLCQAYGMKGKVVSTRDELSGAIAEMLAHDGPFILDVHVTRNENCYPMVAPGKSNAQMLGLPELKQKDLQVELVYCSNCGAKNASTNHFCPECGTKL
>NC_019693.1|WP_015147707.1|1652057_1653329_-|tetratricopeptide-repeat-protein
MIGRIWQQLVRFFRAILGGFKGSSHRSELEPIRDLHPLSNSELEHYFLQLLDGIHKGWQQVKVRRFFEAFSDRVTDERWSDWLQQFGSNLLASPAPNQELARRLQRLGELGYGSVSTTARQIATQLLGREAPSDIHRETPVPNEEPAQNADLTGTQTASTELNLGEISNSVESSETAVPELGAESAQLETVPGLAVSLDELGTVQEQEPPVGIQPLDEPLDVNGWFTRGVERLEAGDDRAALNAFNRVIELDSNHASAWMNRGNALFNLAQAEDALSAYDRAIELRPDDAFSWGARGDALYDLERIDEALTSWNKSLELKPDNADVWYSKGLALGINLGQWDEALTSLEQAIALNANDVQFWFYRGIALSSLNQLEEALTSWDKVLEIKPDFRDAWINKGVVLQKLGRYSEAIEANNQAIGLL
>NC_019693.1|WP_015147708.1|1653386_1653614_-|ferredoxin-family-protein
MPHTIVTNTCEGVADCVDACPVACIHEGPGKNVKGTDWYWIDFATCIDCGICVQVCPVEGAIVPEERPELQQTPQ

Crispr_ID: NC_019693_19

• CRISPR_ID: NC_019693_19
• CRISPR_location: 1798091-1798218
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_19

Consensus_repeat	Method
AATCTCTGATCAGAAGCAACAACTGTCGCCAGAAACCCGGTTTC	CRISPRCasFinder

spacers of NC_019693_19

>19.1|1798135|40|NC_019693|CRISPRCasFinder
TAGCCCCCTACCCAAGTTCAGAAACCGGGTTTCTTCACCC

CRISPR arrays and Neighbor proteins around NC_019693_19

CRISPR arrays

The CRISPR arrays of NC_019693_19

>merge|NC_019693|19|1798091-1798218|CRISPRCasFinder
AATCTCTGATCAGAAGCAACAACTGTCGCCAGAAACCCGGTTTCTAGCCCCCTACCCAAGTTCAGAAACCGGGTTTCTTCACCCAATCTCTGATCAGAAGCAACAACTGTCGCCAGAAACCCGGTTTC

>NC_019693|19|19|1798091-1798218|CRISPRCasFinder
AATCTCTGATCAGAAGCAACAACTGTCGCCAGAAACCCGGTTTC	TAGCCCCCTACCCAAGTTCAGAAACCGGGTTTCTTCACCC
AATCTCTGATCAGAAGCAACAACTGTCGCCAGAAACCCGGTTTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015147800.1|1786443_1787337_-|site-specific-DNA-methyltransferase	unknown	unknown	gnl|CDD|334588
NC_019693.1|WP_015147813.1|1805664_1805952_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156824036.1|1796753_1798016_-|aminoacetone-oxidase-family-FAD-binding-enzyme	unknown	unknown	gnl|CDD|272992
NC_019693.1|WP_015147796.1|1779184_1779757_+|peptidoglycan-binding-protein	unknown	unknown	gnl|CDD|366659
NC_019693.1|WP_044196656.1|1805218_1805485_+|hypothetical-protein	unknown	unknown	gnl|CDD|226980
NC_019693.1|WP_015147806.1|1798240_1799116_-|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224016
NC_019693.1|WP_015147809.1|1800596_1801076_+|DUF4112-domain-containing-protein	unknown	unknown	gnl|CDD|379180
NC_019693.1|WP_015147797.1|1780140_1780788_-|DUF938-domain-containing-protein	unknown	unknown	gnl|CDD|253548
NC_019693.1|WP_015147798.1|1780884_1782294_+|Rieske-2Fe-2S-domain-containing-protein	unknown	unknown	gnl|CDD|215283
NC_019693.1|WP_015147808.1|1799531_1800299_-|hypothetical-protein	unknown	unknown	gnl|CDD|377614
NC_019693.1|WP_015147811.1|1802906_1805165_+|copper-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319783
NC_019693.1|WP_015147807.1|1799146_1799305_-|rubredoxin	unknown	unknown	gnl|CDD|238372
NC_019693.1|WP_156824035.1|1793170_1795066_+|hypothetical-protein	unknown	unknown	gnl|CDD|119405
NC_019693.1|WP_044194669.1|1801367_1802432_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238119
NC_019693.1|WP_015147801.1|1788112_1792762_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|223715
NC_019693.1|WP_156823764.1|1806126_1806273_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147803.1|1795152_1795539_-|hypothetical-protein	unknown	unknown	gnl|CDD|153084
NC_019693.1|WP_044196659.1|1806374_1807934_+|transporter	unknown	unknown	gnl|CDD|224455
NC_019693.1|WP_015147804.1|1795575_1796706_-|glycosyltransferase	unknown	unknown	gnl|CDD|340828
NC_019693.1|WP_015147799.1|1782484_1786339_+|WD40-repeat-containing-protein	unknown	unknown	gnl|CDD|238121

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015147800.1|1786443_1787337_-|site-specific-DNA-methyltransferase	gnl|CDD|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	6.76384e-49
NC_019693.1|WP_156824036.1|1796753_1798016_-|aminoacetone-oxidase-family-FAD-binding-enzyme	gnl|CDD|272992	TIGR00275, TIGR00275, flavoprotein, HI0933 family. The model when searched with a partial length search brings in proteins with a dinucleotide-binding motif (Rossman fold) over the initial 40 residues of the model, including oxidoreductases and dehydrogenases. Partially characterized members include an FAD-binding protein from Bacillus cereus and flavoprotein HI0933 from Haemophilus influenzae. [Unknown function, Enzymes of unknown specificity].	2.94799e-176
NC_019693.1|WP_015147796.1|1779184_1779757_+|peptidoglycan-binding-protein	gnl|CDD|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	1.2749e-12
NC_019693.1|WP_044196656.1|1805218_1805485_+|hypothetical-protein	gnl|CDD|226980	COG4633, COG4633, Plastocyanin domain containing protein [General function prediction only].	3.0642e-08
NC_019693.1|WP_015147806.1|1798240_1799116_-|NAD(P)-dependent-oxidoreductase	gnl|CDD|224016	COG1091, RfbD, dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane].	1.27322e-76
NC_019693.1|WP_015147809.1|1800596_1801076_+|DUF4112-domain-containing-protein	gnl|CDD|379180	pfam13430, DUF4112, Domain of unknown function (DUF4112). This family has several highly conserved GD sequence-motifs of unknown function. The family is found in bacteria, archaea and fungi.	6.90677e-43
NC_019693.1|WP_015147797.1|1780140_1780788_-|DUF938-domain-containing-protein	gnl|CDD|253548	pfam06080, DUF938, Protein of unknown function (DUF938). This family consists of several hypothetical proteins from both prokaryotes and eukaryotes. The function of this family is unknown.	1.00773e-89
NC_019693.1|WP_015147798.1|1780884_1782294_+|Rieske-2Fe-2S-domain-containing-protein	gnl|CDD|215283	PLN02518, PLN02518, pheophorbide a oxygenase.	9.91512e-80
NC_019693.1|WP_015147808.1|1799531_1800299_-|hypothetical-protein	gnl|CDD|377614	pfam06150, ChaB, ChaB. This family of proteins contain a conserved 60 residue region. This protein is known as ChaB in E. coli and is found next to ChaA which is a cation transporter protein. ChaB may be regulate ChaA function in some way.	7.19384e-15
NC_019693.1|WP_015147811.1|1802906_1805165_+|copper-translocating-P-type-ATPase	gnl|CDD|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_019693.1|WP_015147807.1|1799146_1799305_-|rubredoxin	gnl|CDD|238372	cd00730, rubredoxin, Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are believed to be involved in electron transfer.	3.72977e-21
NC_019693.1|WP_156824035.1|1793170_1795066_+|hypothetical-protein	gnl|CDD|119405	cd00219, ToxGAP, GTPase-activating protein (GAP) domain found in bacterial cytotoxins, ExoS, SptP, and YopE. Part of protein secretion system; stimulates Rac1- dependent cytoskeletal changes that promote bacterial internalization.	0.00645006
NC_019693.1|WP_044194669.1|1801367_1802432_+|VWA-domain-containing-protein	gnl|CDD|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	4.87068e-10
NC_019693.1|WP_015147801.1|1788112_1792762_-|PAS-domain-S-box-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	8.83876e-48
NC_019693.1|WP_015147803.1|1795152_1795539_-|hypothetical-protein	gnl|CDD|153084	cd01675, RNR_III, Class III ribonucleotide reductase. Ribonucleotide reductase (RNR) catalyzes the reductive synthesis of deoxyribonucleotides from their corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RNRs are separated into three classes based on their metallocofactor usage. Class I RNRs, found in eukaryotes, bacteria, and bacteriophage, use a diiron-tyrosyl radical. Class II RNRs, found in bacteria, bacteriophage, algae and archaea, use coenzyme B12 (adenosylcobalamin, AdoCbl). Class III RNRs, found in strict or facultative anaerobic bacteria, bacteriophage, and archaea, use an FeS cluster and S-adenosylmethionine to generate a glycyl radical. Many organisms have more than one class of RNR present in their genomes. All three RNRs have a ten-stranded alpha-beta barrel domain that is structurally similar to the domain of PFL (pyruvate formate lyase). The class III enzyme from phage T4 consists of two subunits, this model covers the larger subunit which contains the active and allosteric sites.	0.00140017
NC_019693.1|WP_044196659.1|1806374_1807934_+|transporter	gnl|CDD|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	7.79638e-56
NC_019693.1|WP_015147804.1|1795575_1796706_-|glycosyltransferase	gnl|CDD|340828	cd03798, GT4_WlbH-like, Bordetella parapertussis WlbH and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.	3.84953e-42
NC_019693.1|WP_015147799.1|1782484_1786339_+|WD40-repeat-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	4.20027e-107

Protein sequences

>NC_019693.1|WP_156824036.1|1796753_1798016_-|aminoacetone-oxidase-family-FAD-binding-enzyme
MQGFKAVNDRPVKVVVIGGGAAGFFGAINCAQNHPQSEVTILEAGRQPLLKVKISGGGRCNVTHACFDPGMLVTHYPRGGKALRGAFSRFQVQDTVNWFESRGVRLKTEEDGRMFPTTDDSETIIHCLMQQVRESGVRLRTGVSVVEVRRLSPSEGENVGGFEIVLKSGETLSCDRLLVATGSNPLGYKIAQSLGHQIEPPVPSLFTFNITDPRFQDLAGVAVKMARVQLRDAKLTQTGPVLITHWGLSGPAILKLSAWGARYLYNHKYRATLTIDWLPEYNPELLREQLQAVKSQLPRKAVATSCPFPIPRRLWERLLASRGIDMETRWAEISKKAINQVVEELTRGEYPIQGKGVFKEEFVTCGGVSLKEVNFKTMESRCCPGLYFAGEVLDIDGVTGGFNFQSAWTTSWLAAQMQGS
>NC_019693.1|WP_015147804.1|1795575_1796706_-|glycosyltransferase
MREENDIFVFLEIFSREGGIQSYVKDILTVYGDWASREGRVAEVLLLRDGPDCENPLEGNPGLRFQYLKTLPPMWGRVKLAGVLANRLVLQRPRRVFCGHINLVPLVQVLCQPLGIPYTVLTYGKEVWEPLPKMAQGGLQRASELWTISRYSRDRACAANGLQPSRFELLPCAVDERLFTPGPKPPELIERYGLAGCKVLMTVARLWSGDIYKGVDVTIRALPEIAQAQPDVKYLVIGRGDDQPRLQGLAQELGVSDRVVFAGFVPTEELALHYRVADAYIMPSQEGFGIVYLEAMACGKPVLSGDADGSADPLQDGKLGWQVPHRDPQAVAAACIEILQGEDRRCDGDWLRQQTVGGFGTDAFTLRVKQLIEFTE
>NC_019693.1|WP_015147803.1|1795152_1795539_-|hypothetical-protein
MNQNSYKSLLLNLSDLSRWLMPVFIVWVLISIGLGWVVKSILILIVAITLLPVVAFFGLRWWLSRNLIVDHCPVCSYELTGLNQTQFQCPSCGEPLMGEGDHFVRLTPPGTIDIDAVEVSAKVIEESK
>NC_019693.1|WP_156824035.1|1793170_1795066_+|hypothetical-protein
MAIALNACATLPLKNSTIASRENITQWTSAQKQELRERSTQTQRLSPHSSLDATEVEFQRRSLLIRQRIARQNLEERDRWWRKNDIGDPHKYLLPIILARLSLPEDYDPQPNWDMLLKLERERPDLYHFRSMLDVRIFFLHRNRLPDPVKASYQSMLVSPRVEEWQEGGTENHGFMQRASGLALMDGSGFPVELPHMPETNEAWLRSQLDKFLTIGQGEFHSSTYYGYSIAGLLNLYDFAETPELRELATALLDWYATNMALRLSWGTSGGAESRGFDRYTWNSGLSAVAWIWWGTQNPTNDKAITEAMQLQYARLALAPSLSSYRPPEHLRAIAHKQIPLPFSVQASHPVYYSYHADNHLWETFYVTPDYTVGTLLEGSRDYQVEGTIRAQYATYKLVIRDPNGMNNPIVSLAGTYHSPMATGKTPGDQYVQERSAVIYQQILTESDVEAGVPAQTHLVLPIGYGEPRRHEDWYIWRIQETWLVAQIWGDEIALKMPVSEKEAAYQALAAVGRKTAWIVDVARVAEYPTFNSLIRALEQTEVRDDAWDTDGSLGYKSLAGDQITMTYQPQGAIAIATINGKPRQLENWPVLESPYVRQPLNSGVLEVKEPQLGIWRLRTTATGPQWETKP
>NC_019693.1|WP_015147801.1|1788112_1792762_-|PAS-domain-S-box-protein
MRINPPKKSAKKRSNLANPAHYMGFFSRSEDLLCLLGLEGNFQQVNPAWEPTLGFTPKDLVNRPFIARVHPEDREQTAQEIATLSGEIERVRVQNRYQRKDGAYQWVEWEISPSREEGVMYGFGRKIPDPSDRPNLEPSPTSHHRHSIQSLQDRLRRYQAIATLCPVGIFQSDIDGKCLYVNKKWCELAGISPQEAMGFGWTRSIHPEDSSFVFAQWSQFVQNPVKFCLECRMLRNDGSIIWILVQAVIQTSDHGEVTGFVGAVVDIGDRKQIEEALKQANEDLESRVADRTDEYQGAIGQLQKEITSRTTAEATLQKEREFLNGILNNLTDGIAACDANGRLTLFNQATKDYHGLPEYPIPPEQWAEYYNLYQPDGTPMPVEEIPLFRALRGETIQNVEMVIARKHQKPRTLLASGQAIVDASGNKLGAVVAMRDITERKEAEAALQESQSRLNSILNSLDDMVWSINPNTSEVLFLNPAIETLYGRPRQDFYDNPLLWREMVHPEDKDRVERYDREVMETGSSEIEYRLVRQDGSIRTIQVRCRLIYNPQGQGIRMDGIVTDITDRKEAEKERERLITILEATPDFVGISDANGVVLYLNQTGRRVVGLEADDDITTQHISGFIPESWQSFMFNEALPTAIQDGVWSGETGFLAHDGREIPVLQVIMSHRSESGTVEYFSTIIRDITERKQAEESLQRNALQLALAQQVAHIGSWQCDLNTYDVDWSDELLRIYQVEQPELGLSYEGFLERVHPEDRESLKTVIEEALAQQQPYECKHRMLFPDGAIKFISSKAQPIFNDEGELVKLIGTAHDITASHEAEEALRRSEELYRAIARNFPNGGICLFDPELRYTFVDGRELDEIGFSKTEMEGKTIWEFWPPETAAMLESMYRNALAGETGVFEFPFYQRIYLVHVLPVTHTNGEIFAGMLVAQNITALKEAETALKQREEYLRGILENMPVMMNAFDAEGQFVAWNREGERVTGYSAEEIVGNPHAVEMLYPDSAQREAIFTQMAKLDNHYRNWELDLTAKDGTIKTIVWSNISKQFPIPGWSGWGIGVDVSDRKQAENALRQSEAESRQLANRESLINRISSDIRNSLEVNTILETVVQQLYQLLELERSSFIWYRCCSTPLFWEIVTEVKAPELESRIGRYQVDGNPLEVKFANGELIRSDDLTCEPDLGLQAVYTDWGYRAIVVVSIETSSGDIGCLICGTHQQPRHWQDWEVELLQAVAERLAIALYQADLYRQAQESAREAQEQAEQLQNTLEELQQTQSQLIQTEKMSSLGQLVAGVAHEINNPVNFIHGNLTHLTNYTEDLLSIIRLYQETYPNPEAELEEAITDLELDYITEDLPKILASMKMGTDRIRKIVLSLRNFSRLDEADMKEVDLHEGIENTLLILQNRFKPKGDRHSIELIKEYGELPLIECYASQMNQVLMNIINNAIDALESNPSETVETLPTIRISTEVRGDRAIIHIADNGPGMTEQIKARLFDPFFTTKPVGKGTGLGLAISYQIVVEKHNGILDCITAPGQGSEFIIQIPIVQRKN
>NC_019693.1|WP_015147800.1|1786443_1787337_-|site-specific-DNA-methyltransferase
MPNLPPLINTVIHGDIRTASAIIPDNCIQTIITSPPYFGHRNYTGQQDSPHEIGREQNLTDYIQNLVTCFDRLKPKLKENGLLWVNLGDTYRNKQLIGVPWRVAFALKDSGWILRSDIIWKKPNAMPSSVKNRPTTEHEYIFLFSKTSDYYYDADAIREPHVTFSEQSKMKGGRNHFGKRNSTPEHGKNSGNQNLHDGRWDQAFHPKGRNKRTVWEIPLGKFRDTHFAVYPEPLVEICLFASTQKGDIVLDPFTGSGTTGVVALKHERNFIGCELVKKYQEMAQKRLDETIIQPSLF
>NC_019693.1|WP_015147799.1|1782484_1786339_+|WD40-repeat-containing-protein
MQNPRDFLKTHKLLLGGTAILSLAAFSSGYTALILEAKYAIAGSNLLANVLSGMIANNVGALIDKLRSNPDILKNQDLGKATGLAIALGIRTVADGNEFPEWRDILCALADKTVEYWLRIDPSELVEEELSPLDESQIRYAFAANDGDYDRLRVLDEPQWQILVRGLMQQHQKHLRADVAEYEPAIEAIARHLNEAFPTNLREVLTNDAVGEQAFKKMLLDLERESVGMLRHICDRLDEMPTKAEVTTLLRELETRLPKQNSAQSQQSPPSPKPQLCDSQGNPIARLYNPPNLPLKFLLRPEELAGIKQKLLGDESQKLVRIGVSPPVLVHGMAGIGKTVLAAAVGRDDDVRRRFPDGVVWVTLGQTPDILTLQIDIAGYLLGDRPNFEDTQRGKGQLQELLENKACLLILDDVWEMDHALAFHILGSHHQLLLTAQNTESLHGWGTQRHEVSCLSEPQALGLLAKWAGEHPETFLPPEAAEVAQECGYLPLAVAICGAMVFGKPLNRWQTVLHKLQTANLEKLSQQFPDYRHRNLFKAIQVGVEALLPEVAERYLDFAIFPEDTPIPEAVLVGFWASEGLTKDDVEKVVNTLVQRSLARWDPQDRITLHDLQFDYVRKQVGDISQVQERFLNSYRQRYPQGYHTVEDDGYFFRHLITHHLQHRPEEIRQLLLDFRWLQAKLDAMDVKALVWDFESVHEGEAGTRNPLRLVESAIRISAHILAEDKTQLAGQLLGRLLSLESGPLPEIERVLNQAKNYQAKPWFRPLTNSLNPAGGALLRTLNGHSSSVNTVAITPDGKQAVSASGDKTLKLWDLATGEELATLNGHRASVNALAITPDGKQVVSASKDTTLKLWDLATGKELATLTGHRDRINAVAIIPDGKQVVSASRDKTLKLWDLASGSEMVTLTGHSDQVTAVAITPDGKQAVSASLDKTLKLWDLAKGEELAILTGHSSSVQAVAITPDGKQAVSASWDNTLKLWDLASGSEMATLTGHRSWVYAVAITPDGKQAVSSSRDNTLKLWDLVSGSEVATLTGHRSWVYAVAITSDSKQAVSSSRDKTLKLWDLASGSEMATLIGHSDSVYAVAITPGSKQAVSSSRDKTLKLWDLATGEELATLTGHSDSVQAVAITPSGKQAVSASWDNTLKLWDLASGSEMATLTGHRDSVYAVAITPDSKQAVSASLDKTLKLWDLATGKEVYTLTGHRDSVYAVAITPDGKQVVSVSEDKTLKLWDLETGEIVASFSGESAFLCCAIAPDGVTVVAGEASGRVHFLRLEGLEKGGR
>NC_019693.1|WP_015147798.1|1780884_1782294_+|Rieske-2Fe-2S-domain-containing-protein
MIANEAIALETAPSSTAEPGGNDPHRFDVREVWYPVYYLQDLDKSKIMRFTLLGVDLAIWWDKTGQSWRAFEDKCPHRLAPLSEGRINEQGWIECPYHGWAFSATGKCETIPQQNEGGKAEQSERACVRNFPTAEHQGLLFVYAGNPENAKQTKVPLIDPLEESPDKWVCLNTFRDLPYDALTLLENVLDASHIPYTHHRTVGNRANASKVDLEVIAAGKQGFEGLWEEGPRKGTLGSQQTHFIAPGLMWHDLTSKQFGRTMTVVYATPIRKGECRLFARFPFQFASKVPATFIKLTPQWYSHIGQNAILEDDQIFLYHQERYLEAAGGSEKIAKAFYLPTKADLFVLAFRKWVNEYDADPFPGESFPPLRSREALLDRYHSHTIHCRSCSTALRRIQKLREMAGILAAIAWITAPLLAVIATENTIPTVAISTGITLGLSALWWGLGKLERRFYEGRDIPPRNLPEKK
>NC_019693.1|WP_015147797.1|1780140_1780788_-|DUF938-domain-containing-protein
MNHPHDARRFAPATQRNREPILKVLRRVLPPTGTVLEVASGSGEHAIFFAPRLKPRFWQPSEAEPMLRESILAWMKEVRSDNLFPPIPLNVAESVWSIESPENSQVNVSEITAIIAINLIHISPFTATLGLMAGASRILPVGGILYLYGPYKRGEKHTAPSNASFDEMLQQQNPEWGVRNLEEVEAVALENGLSLQEIVEMPANNLSVVFRREGE
>NC_019693.1|WP_015147796.1|1779184_1779757_+|peptidoglycan-binding-protein
MGGFLEILRHFESALEVNKQMALQQGDTGPQVEQLQRQLEKLGYNIGRFNPNFGPLLNEIVQGFQAEAGLVVDGIVGDRTQTAIDRAVAGITLPSRVSPPPVSPSGDFTTGNWPEWRIVTQGGLNARSGPGFEFPVESTLTGGSIVTRHPDYTNPVQGDRVGKPWLVITNQGTAQFIRANNQFIEPDIQS
>NC_019693.1|WP_015147806.1|1798240_1799116_-|NAD(P)-dependent-oxidoreductase
MKKLLITGSSGFLGWNLCQVAQANWQVFGTYCSHKITLPGCELMPVDLTDFPALKSLFLEICPDAVIHAAAQSQPNVCQTYPEDSYKINVTAASDLAGLCGDAEIPCIFTSTDLVFDGLNPPYAETDAVCPVSRYGEQKVQAEGEMRDRNPQTIVCRMPLMFGEGGPVAQSFLQPMLQTLRSGQDLALFIDEFRTPVSGKTAAQGLLLALKQNEKLLHLGGKERVSRYSFFEQVIEVLEVQQGRIKPCRQQDVKMSAPRPPDVSLDSSKAFNLGYNPLSLRSQLVELLGRI
>NC_019693.1|WP_015147807.1|1799146_1799305_-|rubredoxin
MQQYLCTTCGYVYNPEEGDPDSGIPPGTAFKDIPDDWICPVCGVSKEDFEPD
>NC_019693.1|WP_015147808.1|1799531_1800299_-|hypothetical-protein
MPDDYKAQRTVSAIFQEQQQIDNAIRRLIDRGIPQDHISVMGKNFQSNTRITGFITKKDVILGGLRTGAIFGSLFGSFLSLLTGVGVLLIPFIGPVVAAGPISAVLLGAASGAIAGSAGAGLVSIFVALGMPEEKAAVYQTRLEAGEFLVMAEVPEAKGGEIQLLLESAGGQEIAVNSMTLPRPCAGSCNSPEDLSPEVRTHLSPEAQTTFIQRYNAVLTETADAMKAEQAAWETIHQEYEEDENGVGSKSKVTV
>NC_019693.1|WP_015147809.1|1800596_1801076_+|DUF4112-domain-containing-protein
MITPTDPKLKTLKRLRTLSHLLDNAIRIPGTRFRFGLDPILGLLPAGGDIAGAFLSAYIVFSAAQMGVPRESLVQMVSNILLETLIGTVPVVGDLFDAAWKANVRNMEVLETHLDAPTSDKKADTLFIVLLLGGLMLAVFAIVGVGIWILSSIISAILQ
>NC_019693.1|WP_044194669.1|1801367_1802432_+|VWA-domain-containing-protein
MSVKTIDVVFSFDTTGSMYPCLTQVRRNLKQSVTRLLDEIPGIRIGIIAHGDYCDAGKTYVTKQLDLSGDVDKICDFVQNVEATGGGDAPECYELVLHEAQSLSWSSASTKSLVLIGDDIPHAPAQNPQKLNWRKEVDKLAEMGIPVYGVQALNRSHAKLFYKELAEKSGGFHINLDQFAYITDLFLAVCYQQSSDDQLQAYEAEVTEQGRMSRGLNKMFNTMLNREAKLYHESADLRAVTPGRFQVLDIDKNCAIKDFVIENGLTFQRGRGFYEFTKTETIQGKKEIILMDRATGDLFEGESAREMLGLPPGETVRIKPTNLEKYLVFVQSTSYNRKLLGGTKFLYEVADWDR
>NC_019693.1|WP_015147811.1|1802906_1805165_+|copper-translocating-P-type-ATPase
METVNLKLKGMGCASCATRIEEVIQGVPGVEECSVNFSAEQARVKYNPRRTELDRIQTAVSDAGYTAEPLQELGMRDLDAEQQSRQAEQQELQQKVIFGGIISTILVVGSLPMMTGIDWPFIPNWLHHPWVQFALTTPVFIWCGKSFFVGAWKSLKHHHADMNTLVALGTGSAYLYSLVLSIFPGFFTIQGVMPEVYYEIAAVIITLILLGLLFENRAKGQTSEAIRKLMGLQAKTARVIRQGQEMDIPIQEVGVGDVILVRPGEKIPVDGTVLEGSSLIDESMVTGESVPVKKETGDEVIGATMNKTGSFKLKALRVGKDTVLAQIVKLVQDAQGSKAPIQRLADRVTGFFVPVVIAIAIATFVTWFAIMGNLTLAIITTVGVLIIACPCALGLATPTSIMVGTGKGAENGILIKSADSLELAHQIQTIVLDKTGTLTQGKPTVTDYVTVGGTAHSNEIKLLQLAAAVESNSEHPLAEAVVDYAKAQGVEMPLPAVKNFEAVAGMGVQAIVSSRLVQIGTPRWMQELGIDTQALQTYQENWESEAKTSPWIAVDGKIEGVLGIADALKPSSVTAVRGLRRLGLEVVMLTGDNQQTAQAIAQEVGIHRVFAEVRPGQKADKIKKLQAEGKIVAMVGDGINDAPALAQADVGIAIGTGTDVAIAASDITLISGDLQSIVTAIQLSKATIQNIRQNLFFAFIYNTASIPIAAGILYPLTGWLLNPILAGAAMAMSSVSVVTNALRLRKFNAHHS
>NC_019693.1|WP_044196656.1|1805218_1805485_+|hypothetical-protein
MLKTPKFWIPLLAVATVFTTGTTVTAQEMSEMPGHRPSQSQGIQKIEQPLPVKAGVIVGGVTLIGLELWWFLFSKKKTQPAIDEQESS
>NC_019693.1|WP_015147813.1|1805664_1805952_+|hypothetical-protein
MPINQLRLRKLHRILAPIAILPLLLTASTGILYQMAVVSGNRTQFIGLLDLHQGIFGPINLAPVYPLLNGLGLITLAVTGIMIWFQTRPKRPNRG
>NC_019693.1|WP_156823764.1|1806126_1806273_-|hypothetical-protein
MTQQLKIHRMGIVQGDRDLGIKLALAKISGWAFSCAPDIPVIDAQSGS
>NC_019693.1|WP_044196659.1|1806374_1807934_+|transporter
MGTFRSVITVGMGTLIALSDIGASLGQTEASGDRLPSPTPETAASSGETRDRTAPTEGLQAQGVTPRVENVPEYLTPNPNPLQFPTERDEVEILGTQPLTLEQALQIAEQNSQQLQEALLTVDRNRAALREARAALYPNLGVQSSLSRSSSTGADLANQRQRQQLGDNAPPAEGGNTSLDGGVELTYNLYNSGRRSGQIGLAETQLLVSELDLERVLADLRLEVREAYYNLQESDDQIDISLSAVQSSEQSLRDAEALERAGLGTRFDVLRARVQLADASQALIQAQAQQRIRRREISRILNVSQVVDISAAEPVEISGLWNLSLEDSIVLALRNRAELEQLLLQRELTDYQRQIALSALGPQVNLFASYNVVEVFGDDLNLADGYNVGGRVQWNLYDGGAARARAVQEERNIEIAETRFGQFRNQVRLQVEQAYFNLRSNFENIQTSNIAVDQARESLRLARLRFQAGVGTQTDVLTAETELTRAQNNRLRAIVTYNRALASMERAIGNVNEGLISTP

Crispr_ID: NC_019693_20

• CRISPR_ID: NC_019693_20
• CRISPR_location: 1859390-1859477
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_20

Consensus_repeat	Method
ATGGAATACGCCCCTACAAGAAAC	CRISPRCasFinder

spacers of NC_019693_20

>20.1|1859414|40|NC_019693|CRISPRCasFinder
CACGATGTGTCGGGATTCAATTGAGGGACAAAGAGGGCGT

CRISPR arrays and Neighbor proteins around NC_019693_20

CRISPR arrays

The CRISPR arrays of NC_019693_20

>merge|NC_019693|20|1859390-1859477|CRISPRCasFinder
ATGGAATACGCCCCTACAAGAAACCACGATGTGTCGGGATTCAATTGAGGGACAAAGAGGGCGTATGCAATACGCCCCTACAAGAAAC

>NC_019693|20|20|1859390-1859477|CRISPRCasFinder
ATGGAATACGCCCCTACAAGAAAC	CACGATGTGTCGGGATTCAATTGAGGGACAAAGAGGGCGT
ATGCAATACGCCCCTACAAGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015147849.1|1851274_1851793_-|bifunctional-nuclease-family-protein	unknown	unknown	gnl|CDD|376830
NC_019693.1|WP_156823766.1|1860476_1860734_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147856.1|1859496_1860252_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|181609
NC_019693.1|WP_015147861.1|1867395_1868853_+|signal-transduction-histidine-kinase	unknown	unknown	gnl|CDD|274368
NC_019693.1|WP_015147855.1|1858614_1859295_+|TIGR02646-family-protein	unknown	unknown	gnl|CDD|131694
NC_019693.1|WP_044196680.1|1849136_1849604_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147851.1|1853225_1854914_-|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl|CDD|366703
NC_019693.1|WP_015147863.1|1869684_1870878_-|cupin	unknown	unknown	gnl|CDD|369647
NC_019693.1|WP_015147857.1|1860938_1861547_+|hypothetical-protein	unknown	unknown	gnl|CDD|371751
NC_019693.1|WP_015147850.1|1852113_1852830_+|riboflavin-synthase	unknown	unknown	gnl|CDD|236455
NC_019693.1|WP_044196678.1|1847925_1849116_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270379
NC_019693.1|WP_015147860.1|1866706_1867384_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_019693.1|WP_015147862.1|1868881_1869730_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147859.1|1864975_1866184_+|putative-calcium-binding-protein	unknown	unknown	gnl|CDD|380205
NC_019693.1|WP_015147853.1|1856049_1856838_+|peptidoglycan-editing-factor-PgeF	unknown	unknown	gnl|CDD|224413
NC_019693.1|WP_015147858.1|1861683_1864152_-|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl|CDD|214361
NC_019693.1|WP_015147864.1|1871010_1871316_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147852.1|1854995_1855892_-|biotin--[acetyl-CoA-carboxylase]-ligase	unknown	unknown	gnl|CDD|223417
NC_019693.1|WP_015147854.1|1857281_1858628_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|226459
NC_019693.1|WP_015147848.1|1849977_1851141_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|224370

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015147849.1|1851274_1851793_-|bifunctional-nuclease-family-protein	gnl|CDD|376830	pfam02577, DNase-RNase, Bifunctional nuclease. This family is a bifunctional nuclease, with both DNase and RNase activity. It forms a wedge-shaped dimer, with each monomer being triangular in shape. A large groove at the thick end of the wedge contains a possible active site.	4.34775e-60
NC_019693.1|WP_015147856.1|1859496_1860252_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|181609	PRK09009, PRK09009, SDR family oxidoreductase.	2.80208e-94
NC_019693.1|WP_015147861.1|1867395_1868853_+|signal-transduction-histidine-kinase	gnl|CDD|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	6.46367e-59
NC_019693.1|WP_015147855.1|1858614_1859295_+|TIGR02646-family-protein	gnl|CDD|131694	TIGR02646, Hypothetical_protein_SMc04429, TIGR02646 family protein. Members of this uncharacterized protein family are found exclusively in bacteria. Neighboring genes in various genomes are also uncharacterized or may annotated as similar to restriction system proteins. [Hypothetical proteins, Conserved].	1.49878e-20
NC_019693.1|WP_015147851.1|1853225_1854914_-|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	3.99252e-46
NC_019693.1|WP_015147863.1|1869684_1870878_-|cupin	gnl|CDD|369647	pfam08007, Cupin_4, Cupin superfamily protein. This family contains many hypothetical proteins that belong to the cupin superfamily.	1.51523e-23
NC_019693.1|WP_015147857.1|1860938_1861547_+|hypothetical-protein	gnl|CDD|371751	pfam11833, CPP1-like, Protein CHAPERONE-LIKE PROTEIN OF POR1-like. This entry includes proteins from bacteria and eukaryotes. The plant member, CHAPERONE-LIKE PROTEIN OF POR1 (CPP1), is an essential protein for chloroplast development, plays a role in the regulation of POR (light-dependent protochlorophyllide oxidoreductase) stability and function.	5.1346e-77
NC_019693.1|WP_015147850.1|1852113_1852830_+|riboflavin-synthase	gnl|CDD|236455	PRK09289, PRK09289, riboflavin synthase.	1.16563e-85
NC_019693.1|WP_044196678.1|1847925_1849116_+|extracellular-solute-binding-protein	gnl|CDD|270379	cd13661, PBP2_PotD_PotF_like_1, The periplasmic substrate-binding component of an uncharacterized active transport system closely related to spermidine and putrescine transporters; contains the type 2 periplasmic binding fold. This group represents the periplasmic binding domain that serves as a primary polyamine receptor of an uncharacterized ABC-type transport system from plants and plant-symbiotic cyanobacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, as well as plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.88647e-104
NC_019693.1|WP_015147860.1|1866706_1867384_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.91169e-79
NC_019693.1|WP_015147859.1|1864975_1866184_+|putative-calcium-binding-protein	gnl|CDD|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	6.43935e-20
NC_019693.1|WP_015147853.1|1856049_1856838_+|peptidoglycan-editing-factor-PgeF	gnl|CDD|224413	COG1496, yfiH, Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism].	2.43832e-67
NC_019693.1|WP_015147858.1|1861683_1864152_-|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl|CDD|214361	CHL00095, clpC, Clp protease ATP binding subunit.	0
NC_019693.1|WP_015147852.1|1854995_1855892_-|biotin--[acetyl-CoA-carboxylase]-ligase	gnl|CDD|223417	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism].	6.36756e-62
NC_019693.1|WP_015147854.1|1857281_1858628_+|AAA-family-ATPase	gnl|CDD|226459	COG3950, COG3950, Predicted ATP-binding protein involved in virulence [General function prediction only].	1.45512e-34
NC_019693.1|WP_015147848.1|1849977_1851141_-|aldo/keto-reductase	gnl|CDD|224370	COG1453, COG1453, Predicted oxidoreductases of the aldo/keto reductase family [General function prediction only].	1.28091e-137

Protein sequences

>NC_019693.1|WP_015147855.1|1858614_1859295_+|TIGR02646-family-protein
MKRIRKTHPPREFLEWLKENEGLDCSYAALQGKEAHIVLKNHLLREQGFICAYTGVSISEEESHIEHIKPQSVCRTVPNPGKTYLEDVEYRNMVACFPQDGGDVSHGYGAPIKGGWWNEEQFVSPCQEDCERRFIYGWRGKISPSQENDTAANTTIDILELNAKSLKDRRYRAIVGFFGFSSKYKTKELGQREAKALLTIIGKPNSGGKLQEFCFVFEQLSPKYIK
>NC_019693.1|WP_015147854.1|1857281_1858628_+|AAA-family-ATPase
MRIDKLIIHNFKKFSEYSLELHPKFTLLIGDNGTGKTSLLDALAIAAGVWLVNPPDSTLSNSKRNILPNEIRLKPIKHAGITRFFECKPVIIQAIGMIHEDYSYYNHWCRQIKINGSRTSNTEAKRVIDSISILFKRDQFGEMIWFPVIGYYGAGRTWLPSNVSRKTAKLEQGINRRWEAFYDCFEERIRLADLQTWFQKEAIAALQRSGKMRPSYDVVKWAILRCIPGADDLWFDGDRAEIVISLEHQPIPFSNLSAGQKMMVALIADIAIKVVNQNTKFLPEVIDPNPEIIPPILQQTPGLVLIDEIDVHLHPKWQRRIVNDLKTTFPSIQFVCTTHSPQVIGQIEPECLRILYEDNTGKICTITPKQGLGMDSSWILQNLMGASARDIKIEQDLEQIFDTINDENYSQARELIQTLKQKVGDFPELQEATSFLDRLELLKDYETD
>NC_019693.1|WP_015147853.1|1856049_1856838_+|peptidoglycan-editing-factor-PgeF
MHTWHWRNWNGLPYLTCSLLEPWPHGFFTQQFWPRSPEELVEVLQPTASVYRVKQVHGNTVLSTETLTPQVREDELEEDAPQKPEADGLMSAGSSEALWVCSADCSPVLIGDMRSGQVAALHSGWRGTADNIVAVAIADMVNQGSQLEELRVAIGPAISGPVYQVNTEVAIQTCASLVDLDHPEDILKTVQDFDNSPILPDSEPGKARLDVRRTIELQLEQLGITSAQVAISPHCTYQDPENFFSYRRDGLKKVQWSGIVSR
>NC_019693.1|WP_015147852.1|1854995_1855892_-|biotin--[acetyl-CoA-carboxylase]-ligase
MGLNQDDIENILRGLRSQHTVNPGMTDGGFASHPSLSPSSLDFSIQICDQVTSTNETLWTLLADGAPPGTVVIATRQTAGKGQRGRQWESSPGGLYLSLALTPNLNARDALLLTLCSAWGLATTFRAYNIPVSLKWPNDLILEGYKLGGILTETKIHQGQITKAVVGVGINWSNPVPETGISLQRFLGDRPYPEITSLEMLAALTLWAVASGYQTFDQKGVGTLLPSYQNLMVGIGQPVAVEGSAGVVLGVSDTGELRVRLKRSPASEPNSAFTSASNPEEIELMPGTINQGYPILRA
>NC_019693.1|WP_015147851.1|1853225_1854914_-|peptidoglycan-DD-metalloendopeptidase-family-protein
MSQRNQLSRTPLSIICQVSLLLQGLALIPSLSLLGGDTDANAQTPSDAADPFGQAEMAPPPVESLPSEPEVSTSAELLQPLEGSDYSVSGFVEETPADPWFAEDASPDPLDSAGVTPWSPESDLAPETLRAQPDPIGDYTREAIAPPEDYPTPETASAESTLQNIHQSNLYVDPTDYSLPTPNNPPAAEANALATPASEESDSFTATAPPPPELVEQAAGVGEPIPVAASQEIEQHRYTEDQLPVPASIQQAQQANLYSPTLQPLEPPAIAAPVGTVSAPAEPVYYTEPEPSYAALPQVPVRTGNAYPQASAKADIDGIHYRTKTAARNFDWNRLRRSKRPGNGNTSMIFPLAIPAEITSLFGWRIHPIFGDSRFHSGMDFGAPTGTPVVAAYSGTVSIADWMGGYGQTVVLQHQNSTLETLYAHLSNIFVQPGEVVEQGQVIGEVGNTGNSTGPHLHFELRELTPEGWMAMDPGTQLEYALAQFIQSLETVPQIATSASDNSTLMTLPSLEMPAPPPPVAFLNSPVNLETASTTLLDVPTPPPLPLPPVPVTLEITIPQTE
>NC_019693.1|WP_015147850.1|1852113_1852830_+|riboflavin-synthase
MFTGLIQGLGTIEATGTENLKISCHSGAETVLTDLELGDSVAVDGVCLTVVEILPRGFVAIASPETLDRTTLGTVSHTYVNLETSLRVGSKLGGHFVTGHVDAIGCLQQSIQTASSWSMTFTAPPGSPSLWQRQIAPYLVPKGSIAVNGISLTIADCDEQGTYFTAAVIPHSYGETNLRYLQLGHWVNLEADILGKYVGKFIRSSFGSPLSDIPSDDVTPSLSFDQISPSFLAEHGYL
>NC_019693.1|WP_015147849.1|1851274_1851793_-|bifunctional-nuclease-family-protein
MIEMKVAGIALDAATRSPIVLLRDAGDRRALPIYIGQDQARSIISALESQKPPRPLTHDLMVNILEEYELSLDRIIIHTLQDNTFYAVLKLRHGEVLKEIDARPSDAIALALRTNSPIWVMEEVVADASIPVDREADEAERQAFRDFVSNISPEDFIQRKEFGSGSGEVQES
>NC_019693.1|WP_015147848.1|1849977_1851141_-|aldo/keto-reductase
MDYRRFGKTNLALSIFTLGTMRYLASPENAIATIKAAVKRGINHIETARGYGNSEEYLGVALMELLQGNSPLQREQLYITTKLSPVGNAEEVERYIDESLDRLKVNYLDGLAIHGINTRQHLEWVLDDHGGMQGINQALRDGRVRHLGFSTHGSLDLILATLNTDLFQFINLHYYYFFQRNAAAIALAHQKDLGIFIISPADKGGKLHTPPEQLSQLCHPLTPLEFNYQFLLSDPRITSLSLGAANPEELTLLDRLSLLQNAIDQNDSTAIPIPQDTINRLETHATKVLGSDQCSQCYACLPCPETINIPEILRLRNLAVAYSMTDYGQYRYSMFENAGHWFPGMKGNRCSNCGDCLPRCPEQLNIPALLEDTHDRLKGKSGRRLWG
>NC_019693.1|WP_044196680.1|1849136_1849604_-|hypothetical-protein
MVPPDDREQPALELQQMPPEKPPLQFLTIPPEIDPAEFNITTNYTISQTGKTIPSLWWVNEQFGNRLVENWLAYPRNGENTGTVDVIVNRQTWSLLDYLQRYEFLNHFGQVARDYGYNIRVFTRQQRLLGTYTCTSEPVACNLWLDSQGLDSQAP
>NC_019693.1|WP_044196678.1|1847925_1849116_+|extracellular-solute-binding-protein
MNRRSFLMSLSTLALAQVLSGCGTVDRQTLKILLLKSSIPAQAMGEFRKQLDNRAVLNFSPAAQLDELFRLLQQWKNSPSNNSGRRWNLPLPWINRDAGPSNLADLVTLGNYWLERAIAQELILPLDPTPLDQWDNLPSQWQTLVRRNAEGQLDPEGQVWGAPYRWGTTVIAYRVDRFRNLGWTPQDWSDLWRPELRDRLSLLDSPREVIGLTLKTLGHSYNRDRLDDLPELQEQLLALHRQARLYSSDAYLQPLLLGDTWVAVGWSTDILATMQRNPQIRAVVPPSGTALWSELWVRPAGPNPVNPETPTPASSLANQWINFCWNPEMAVQLSQLSKAASPMLLNRDRGELPNALQTNGILLPTAEAIANSEFIEPLTPEIAETYEALWREIRLS
>NC_019693.1|WP_015147856.1|1859496_1860252_-|SDR-family-NAD(P)-dependent-oxidoreductase
MNQSQNALIIGASQGIGLGFVKKCLESPSISTLFATYRHPDSAAELLNLSRQHCDRLICLPLDITDEAQIQEMTGQIQAHSDSLHFVINCVGLLHDSTLQPEKSLRQINSENLMRYFQVNSIGAVLLAKHLLPFFQHNQRSIFATISAKVGSIGDNQLGGWYGYRASKAALNMLMRTVAVEYSRKGANAIVITLHPGTTDTRLSKPFQRNVPPEKLFPIEKTVSQLWTVLENLEQTDTGEFFSWDGTRLPW
>NC_019693.1|WP_156823766.1|1860476_1860734_+|hypothetical-protein
MTPDSSGIADRPMGDPLCNWQREKDISRAHMGKLFSRGTPNIWGFELKLRHRWADCLGNVCDRLGTMRKQSRYSSNYSKGTPIFL
>NC_019693.1|WP_015147857.1|1860938_1861547_+|hypothetical-protein
MSELSCYEQLGVSENASFEEIQEARTRMSELHSGDRKQVDLIEAAYDEILMQRLRQRQEGKIKVPERIRFAEREVRTMPAAPPTPTKEAPAWLQRLLDTPSRSDIIWPAGGFFALSLLSLLQPASAPLALAVGVGVGLYFLNRKEKKFARALVITVVALLGGLLIGAPLGTWLTSLGVLFSADGLAASFTFFVLWLVSSFLR
>NC_019693.1|WP_015147858.1|1861683_1864152_-|ATP-dependent-Clp-protease-ATP-binding-subunit
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDARIEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLSKVRTQVIRMLGETAEVTSGASNARTKTPTLDEFGANLTQMAAEGKLDPVVGRQKEIERVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIANNDVPDILEDKRVVTLDIGLLVAGTKYRGEFEERLKKIMDEIRSARNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDEYRKHIERDAALERRFQPVMVGEPTVDETIEILFGLRDRYEQHHKLKISDEALDAAAKLSDRYISDRFLPDKAIDLVDEAGSRVRLINSQLPPAAKELDKELRQVLKDKDDAVRSQDFDRAGELRDREMEIKAEIRSIASNKKTGVSDSELSPVVTEEDIAQIVASWTGVPVNKLTESESEKLMHMEDTLHQRLIGQEEAVKAVSRAIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKALASYFFGSEEAMIRLDMSEYMERHTVSKLIGSPPGYVGYNEGGQLTEAVRRRPYTVVLFDEIEKAHPDVFNMLLQILEDGRLTDAKGRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFEQNQADAQYNRIRSLVNEELKNYFRPEFLNRLDEIIVFRQLVKDEVKLISEIMLKEVFSRLTEKGITLEVTDRFKERLIEEGYNPAYGARPLRRAIMRLLEDVLAEEILSGRVKEGETALVDIGEEGQVIVRPGEQRELLPQSAE
>NC_019693.1|WP_015147859.1|1864975_1866184_+|putative-calcium-binding-protein
MVVNIGQLPVQPDVMVTIAGTVVAVREDEFLLQDSTGQIWVEPANGARVNVNIGDQLTIVGDRDDVEDFDAISITRTNSPEPIQIFALPGVTPPVPEPTPPVVSTPLNTSPVQNIGQLPVQPDVMVTVAGTVVAVREDEFLLQDSTGQIWVEPQAGSWNGFNLNIGDRVTVLGDRDDVEDFDAISVIRSNSPVVIPLNWQNPGGQNPLQGTPMDDVIAGNPIIPNSINGQSGNDTLFGGEGDDILSGNAGQDMLLGLSGNDIIFGGKGDDTLWGNQGQDMLLGNLGNDLLFGGKDSDFLDGGEGNDTLSGDLGQDFLTGGPGNDVFVLSSETAATDLATADRVLDFEIGFDRIQLNPGLTFADLSLEAIDLGTAIRVPQFNQVLGIIDNVTPSMLSANDFLV
>NC_019693.1|WP_015147860.1|1866706_1867384_+|response-regulator-transcription-factor
MRILLVEDDPEQLEPLHNALTRSGHIVDGVAEGTDARWLIGEKDYDLLILDWMLPGEDGVSICKFYREGGKTSPILMLTAKDTTADKVRGLDAGADDYLVKPVDVEELLARVRALRRRSPLWIGDILEVGDLSLNLDTMRLTRGDRSIKLASRDFQLLEYLMRNPGKVISRDRLEQALWEWGEEPESNAVASRVKRLRKRLQELEIETWIETVYGVGYQFEPQNN
>NC_019693.1|WP_015147861.1|1867395_1868853_+|signal-transduction-histidine-kinase
MNGLKTSLNCWQKLPTRIRGTLIIAIPVTCLFTTLSAFAWLKFNLIEDEEWVQHTQIVRLETKRLLNALLDAETGVRGYGLTFREEFLNPYNQAIPIIPNSLERLQYLVTDNPEQTLLLQEIKTITQENLEIFDQKITLQSEVNKLRDSDEVWVPADALYEWLEEGKATMDEARLLIDRFAETEENLLEKRQIHQKFYRQVTWNILCISAGVGVLGFFLSIHLFYKLEQELATREVNLKASNQRLEMVCEQLQRFTANASHELRTPLAAVLSNAQVGLMDIADLEELQEDGEDYIPLKKRLQKIVETTKKMSDLVGQLLFLARHEGGLNSESLNPVDLAPVLKQLIADFFPETQAKSLDLTYHCTQTVIPVKADISLLPQAVINLLSNACRYTPAGGKIELSVSTAENWAIIEVKDTGVGIPPDALPHIFERFYRVDKKRYETVKGFGLGLAIAQQIVQIHGGNLEVSSILNQGSIFTIRLPLSH
>NC_019693.1|WP_015147862.1|1868881_1869730_+|hypothetical-protein
MTKILPLGHLFPTNQEGFILNDCHPDKILPPWTSLVEELCQTCLQIWPSRLQALYLRGSVPRGLAILNGSDLDSFALLSGEITPQDIEQSRQLCQTLKRRYLFCKKVELILFNDRLIHNTNSIWPVIIQTESLQIAGNFIPKTLKVKPGPDLISYSYTWKSDLANTLKSLECLSPRALDYSNQVKKQCAWIARRLIRVGFELVMEQDQCYTPDLYQCYQRFSAYFPEQKKSMKKALELAINPSANRAGLIIFLRRFGRWLEGEVHRKFYSSIEEEPSTNKIP
>NC_019693.1|WP_015147863.1|1869684_1870878_-|cupin
MDIFEFLLYPYATPQFFAENWTEIALFIPGKSRDKFAGLFGWNQLNQLLNYHFIPYPNLRFSLDGESLPATPSHQWLERLHQGATLIIDSVHERVPELEKLVADVREQTGYRSQINLYCSPSDQQGFNCHYDTHDVLILQIEGEKDWFVFPETVPFPVTGMRSKDQIPPDVPPYLECRLQPGDLLYIPRGHWHYAIASSNPSRDDYSPSLHLTLGIDCQTGLDWMNWLGKELQENTQWRASLPVIPSGDRTAVQPYLEKLRDRLLEFLEDPETITGYLDDLNYRDRTPLPFAFPHQLGSQIFDFGLETRFIPSALHPVQIISLEDHQTQVIIGAKQATIKGIPTDVVEKLFRPGGFSLLDLADWCPSLDVETGVIPLLTRLVTQGILFVDGSSSIEE
>NC_019693.1|WP_015147864.1|1871010_1871316_-|hypothetical-protein
MIFDLKSSNLIMACLLSAKASLLLVAPSQSALSSSPVNLAGNSSVEVEVVNLTNNSPNSSESAWLFSDADVDRNVDRNVDQDVDQDTDRNQAGQTSFIRQV

Crispr_ID: NC_019693_21

• CRISPR_ID: NC_019693_21
• CRISPR_location: 2008762-2008876
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_21

Consensus_repeat	Method
GGTTTCTGACCCAGATTTGTGACCATTGGCAAA	CRISPRCasFinder

spacers of NC_019693_21

>21.1|2008795|49|NC_019693|CRISPRCasFinder
GATTGGGATAAAAACCCGGTTTCTAACCTTTGCGGGGGACAAGAAACCG

CRISPR arrays and Neighbor proteins around NC_019693_21

CRISPR arrays

The CRISPR arrays of NC_019693_21

>merge|NC_019693|21|2008762-2008876|CRISPRCasFinder
GGTTTCTGACCCAGATTTGTGACCATTGGCAAAGATTGGGATAAAAACCCGGTTTCTAACCTTTGCGGGGGACAAGAAACCGGGTTTCTGACCCAGATTGGTGACCATTGGCAAA

>NC_019693|21|21|2008762-2008876|CRISPRCasFinder
GGTTTCTGACCCAGATTTGTGACCATTGGCAAA	GATTGGGATAAAAACCCGGTTTCTAACCTTTGCGGGGGACAAGAAACCG
GGTTTCTGACCCAGATTGGTGACCATTGGCAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_044196720.1|2006674_2006968_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147970.1|2010958_2011807_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223377
NC_019693.1|WP_044194740.1|2016897_2017704_-|TPM-domain-containing-protein	unknown	unknown	gnl|CDD|377378
NC_019693.1|WP_156823776.1|2006313_2006487_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147975.1|2018037_2018403_-|DUF1823-family-protein	unknown	unknown	gnl|CDD|370156
NC_019693.1|WP_015147964.1|2006137_2006317_+|hypothetical-protein	unknown	unknown	gnl|CDD|177653
NC_019693.1|WP_015147976.1|2018514_2023698_-|hypothetical-protein	unknown	unknown	gnl|CDD|238121
NC_019693.1|WP_015147967.1|2007549_2008737_+|WD40-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|238121
NC_019693.1|WP_015147962.1|2004028_2004622_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NC_019693.1|WP_015147969.1|2010022_2010352_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015147963.1|2004915_2006004_-|alanine-dehydrogenase	unknown	unknown	gnl|CDD|240630
NC_019693.1|WP_015147971.1|2012891_2013155_+|DUF4212-domain-containing-protein	unknown	unknown	gnl|CDD|379403
NC_019693.1|WP_044196727.1|2024836_2026219_-|KAP-family-P-loop-domain-containing-protein	unknown	unknown	unknown
NC_019693.1|WP_015147973.1|2015248_2016760_+|WD40-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|238121
NC_019693.1|WP_015147960.1|2000677_2002612_+|GHKL-domain-containing-protein	unknown	unknown	gnl|CDD|226654
NC_019693.1|WP_156823775.1|2002659_2003784_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044194736.1|2007010_2007457_+|heavy-metal-responsive-transcriptional-regulator	unknown	unknown	gnl|CDD|133398
NC_019693.1|WP_015147968.1|2009000_2009939_+|hypothetical-protein	unknown	unknown	gnl|CDD|223691
NC_019693.1|WP_015147959.1|1994527_1999954_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NC_019693.1|WP_015147972.1|2013158_2014850_+|cation-acetate-symporter	unknown	unknown	gnl|CDD|274698

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_044194740.1|2016897_2017704_-|TPM-domain-containing-protein	gnl|CDD|377378	pfam04536, TPM_phosphatase, TPM domain. This family was first named TPM domain after its founding proteins: TLP18.3, Psb32 and MOLO-1. In Arabidopsis, this domain is called the thylakoid acid phosphatase -TAP - domain and has a Rossmann-like fold. In plants, the family resides in the thylakoid lumen attached to the outer membrane of the chloroplast/plastid. It is active in the photosystem II.	1.39978e-08
NC_019693.1|WP_015147975.1|2018037_2018403_-|DUF1823-family-protein	gnl|CDD|370156	pfam08853, DUF1823, Domain of unknown function (DUF1823). This presumed domain is functionally uncharacterized.	1.97664e-78
NC_019693.1|WP_015147964.1|2006137_2006317_+|hypothetical-protein	gnl|CDD|177653	PLN00014, PLN00014, light-harvesting-like protein 3; Provisional.	3.90019e-08
NC_019693.1|WP_015147976.1|2018514_2023698_-|hypothetical-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	7.67295e-93
NC_019693.1|WP_015147971.1|2012891_2013155_+|DUF4212-domain-containing-protein	gnl|CDD|379403	pfam13937, DUF4212, Domain of unknown function (DUF4212). This family includes several putative integral membrane proteins.	7.25976e-35
NC_019693.1|WP_015147962.1|2004028_2004622_-|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.01944e-28
NC_019693.1|WP_015147970.1|2010958_2011807_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	3.70547e-64
NC_019693.1|WP_015147963.1|2004915_2006004_-|alanine-dehydrogenase	gnl|CDD|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NC_019693.1|WP_015147967.1|2007549_2008737_+|WD40-repeat-domain-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	3.90107e-69
NC_019693.1|WP_015147960.1|2000677_2002612_+|GHKL-domain-containing-protein	gnl|CDD|226654	COG4191, COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms].	2.88231e-50
NC_019693.1|WP_015147973.1|2015248_2016760_+|WD40-repeat-domain-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	1.27211e-74
NC_019693.1|WP_044194736.1|2007010_2007457_+|heavy-metal-responsive-transcriptional-regulator	gnl|CDD|133398	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators. Helix-turn-helix (HTH) heavy metal resistance transcription regulators (HMRTR): MerR1 (mercury), CueR (copper), CadR (cadmium), PbrR (lead), ZntR (zinc), and other related proteins. These transcription regulators mediate responses to heavy metal stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	9.50263e-49
NC_019693.1|WP_015147968.1|2009000_2009939_+|hypothetical-protein	gnl|CDD|223691	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only].	8.30066e-24
NC_019693.1|WP_015147959.1|1994527_1999954_-|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	0
NC_019693.1|WP_015147972.1|2013158_2014850_+|cation-acetate-symporter	gnl|CDD|274698	TIGR03648, Na_symport_lg, probable sodium:solute symporter, VC_2705 subfamily. This family belongs to a larger family of transporters of the sodium:solute symporter superfamily, TC 2.A.21. Members of this strictly bacterial protein subfamily are found almost invariably immediately downstream from a member of family TIGR03647. Occasionally, the two genes are fused.	0

Protein sequences

>NC_019693.1|WP_015147967.1|2007549_2008737_+|WD40-repeat-domain-containing-protein
MERFRLKNPVLTQGLIPRLLAYLPALPLLLGTALFPLGEITRATPQPRMPDPSSVQSSLSWGTLSNSRIQGQDDRPIPLSWNNPELFLAIEGESATIQSLAFSPDGRFIALGGGRNDPRIEIWDLQQEKRIHHWKTYQNRVLALTFSPDGNTLVSSGDGGAIEIWDVQEGKLLHQFLEHRSNVLSLAISPDGRNLVSGGLDGIRFWDLRDRQLIQVLLNLQPIYSVAFRGDGQLIAAGTHEGNVILWPVIPGEGIAIVGNPLATSFQHDRGITTLDFTPDGNRLISGSFDATIKCWDLVNRELVYTLVDHPSWIKSLKINPNGQLFASASRDGIRFWNLETGEAVGFISSESDWAQAIAWYPDGLTLATGGLDRIVNLWRGGMGPNEDAIASPNP
>NC_019693.1|WP_044194736.1|2007010_2007457_+|heavy-metal-responsive-transcriptional-regulator
METLVGEKSLKIGEVSATSGLPVKTIRYYEEIGLLEPTVDRADSGYRIFDSTVLNRLAFIKRSQSLGLSLTEIKEILQVHDRGELPCGEVRHHLEAKVAAIDEQIRSLETLRSELQGILQGWQESPPKDQIAQTICPNIQQDCHHHGD
>NC_019693.1|WP_044196720.1|2006674_2006968_+|hypothetical-protein
MNPGLIRFLKSAYRQEPITSFIVIVGAVDAALGGIDQSVSLFSFGIVLVSVALALRWWQLQRSQPVDLERVPEHYLPPASSRQPLPLLMTSKKYPPQ
>NC_019693.1|WP_156823776.1|2006313_2006487_-|hypothetical-protein
MERRVQPGQPTDGFCPDRSNSGGLSVPPGGVKPLPIPEVQVQGADGDDPPARLQEMT
>NC_019693.1|WP_015147964.1|2006137_2006317_+|hypothetical-protein
MTEPQPIGPTVTPNLEEPKFGFNKYAERLNGRAAMIGFALTLLIEYLTGQGLLSWLGLS
>NC_019693.1|WP_015147963.1|2004915_2006004_-|alanine-dehydrogenase
MEIGVPKETKDREYRVGLSPSSVRVLTEQGHSVFIETHAGVGSGFSDQEYLHSGGKIVPTAKDAWSQELVVKVKEPLPGEYGYLHKEQLLFTYLHLAADRQLTETLMESGVCAIAYETVELPDRRLPLLTPMSIIAGRLSVQFGARYLERQQGGRGVLLGGVPGVKPGHVVILGGGIVGTEAARMAVGMGARVQILDINVDRLAYLETLFGSRVELLYSESLQIEAAVSDADLLIGAVLVPGRRAPILVPRQLVETMRPGSVIIDVAVDQGGCVETLQPTSHTNPTYIEAGVVHYGVPNMPGAVPWTATQALNNSTLPYVVKLANNGIKALDFDAALSKGLNVKNHQLLHPDVQHGFPDLVP
>NC_019693.1|WP_015147962.1|2004028_2004622_-|GNAT-family-N-acetyltransferase
MKIFLETDRLILRYFNDTDVHHLLELDSDPTVMRYINGGISSNLADIEAGLERIFDYYENYENFGFWATHEKVSGEFIGWFHFYPAITSSFGVAANLVREGEIALGYRLRQSSWGKGYGTEGARSLRDKGFNEWGVNRIIAWALQANQASIRVMEKVGLQLECDYQLKPEQLPALKQPEERLILKYGCDNIKFLPRE
>NC_019693.1|WP_156823775.1|2002659_2003784_-|hypothetical-protein
MTYAIHKGKVRNPLLSSLFAGVSGLAIYSSLFWGAYWRFQQRFTQFLSPLEQEIFYSSDKSIDEYLQEKTGKPGFLGYVKYSAQKAVVIQKAVKGDFAFNETLNWLYWLVELSIIEGIIVTFSYSAAKKPFCEACDMWYSQPERVGNVKGRFYRNFLTLIQDENYFKAAELVKANTHPYSPSIEVELQRCPCCQTSDVVMKLSRVGLDAQGGLTFKPIQVGIITQHQAQQFIELSHPQLLEKLEDSAAILPDEAGILVAEERTTVKDSDEFLSHGLQDSQIEQVVQQLAQYRAIKTAYFLQKKVQTLPEKPVYILGFVRRRPLGYESDIADIKIVHQLYGEMELPEQTLIVDLKKHKKIAKKIQQVPGSMIYKS
>NC_019693.1|WP_015147960.1|2000677_2002612_+|GHKL-domain-containing-protein
MERSPAPVQFRKNLFLIPTIALFYCVLGLLGLKLAVLPGEVTAVWIPAGVGLGAVLIWGNRIWPSIALGSFGISVLLSPTPLSLAVGVVTAVGNTLTPLWGAALIRRLTHTRYPFHRVNEVFIFVACGAIAAQTISATVGILALCVAQWVDWSNFAQSWVTWWVSNVAGVLIFTPVLLTWHHFFSQSWQQRKGTRIFSHLGKIVGQELRSLRLESFSWFLLFDGVVSLAFWYGYPVEYLMIPLLGWAAFRFSERWTTLAIALTGLMAIAGTILNRSSFVRDNLNAALLFLESFIGVISVTTLVLIAVLEERRQALEGLKQAKAELEYRVIERTQELSQANEQLMRQEIHLTEKAESLANALRQVKQTQGQLIHNEKMISLGQLVAGIAHEINNPVSFIYSNLSPATDYFQDILDLLSLYQEKYQDPDPEIVKLESQIDLPFIKKDLFKLLNSMKSGADRIQRIVLSLRNFSRLDQAQLKAVDIHEGLESTLLILQHRIQGSESLPPQIEVIKDYSPLPPVECLAGELNQVFMNLLSNAIDAIEAHAPANSGRIHIQTLELEDEQIQIAITDNGGGIPPAVQNKIFDPFFTTKPVGQGTGLGLYISYEMIVQKHHGTLICRSEPGVSTTFEITLPLRNTSDSNLE
>NC_019693.1|WP_015147959.1|1994527_1999954_-|AAA-family-ATPase
MNNVTSLPGYEITEELYRGTRTLVYRGIRRDDHQPVVIKILRNLYPNFNEIVQFRNQYTIAKSLNFPNIIKPLSLKFHQNRYLLVMEDFGGISLSNYFKFSSTIGAEIHKCSITEFLKIGIQISEILHYLYQTKIIHKDIKPANILINPDSKEVKLIDFSISSLLPRETQEIQNTSELEGTLAYLSPEQTGRMNRGIDYRSDFYSLGVTCYELLTGQLPFVSEDAMELVHCHLAKQPIPIHEINPQIPLVLSEMVMKMMAKNAENRYQSALGIKHDLEECLAQLEQKGHIEYFKIGQQDISDRFIIPEKLYGREAEVNQLLNAFERVSQNSTEIMLVAGFSGIGKSAVINEVHKPIVRKRGYFIKGKYDQFKRNIPFDAFVQAFQDLMRQLLSESDSQLQAWKTELLQVLGENGQVLIDVIPELENILGEQPPAPELSGDAAQNRFNLLFQKFVQVFSSEKHPLVIFLDDLQWADSASLNLLKLLMQETRYLLILGAYRDNEVSLVHPFILTIDEIVKTGARVNTITLSPLNETHLNQLVADTLNCQLSLAESLTQLIHQKTQGNPFFATQFLRALYDDKLITFDRNQSSFARGGKPGGWQCDIAQIKTLAITDNVVEFMALQLQKLPIETQEVLKLAACIGGEFDLKTLMIIREKSQEITATDLWKALQEGFVLPTTRIYKFFTQSDGEEVFQGSVNPSYRFLHDRVQQSAYSLIPDPQKQVTHLKIGQLLLSHTSVTEQEEKLFEIVNQLNLGKSLISKRSEQTQLAQLNLKAGQKARATTAYTATFEYAMTGIELLGEEGWESQYEMNLALYETATEAAYLNGDFLQMTQLKTRVLEQAKTLLDRVKVYEIEIQAAQAQSQPSQAVKIGLQILKQLGVSFPDQPTLQDIEQALQHTLSLVGGRQPTDLIALPQMTDPTQLAIMGILAGVTASAYVATPTLLPLIMLKQVNLSLEYGNSAFAPNGYCGCGLILCGVVGDIESGYQFGQLALFLLEQLDSKKLKAKTYGQVKSCISHWKEPLVNTLAFFREGYQNGLETGDLEWGGICAILYLMHAWFAGQELSDLSREGAAFCAQFAQQKQKTMAKQGAIFQQAIVNLLGSSTEAWQFKGDIFSEAEDLPIFLEVGNQTAPCYLYVSKLVLCYLFGQIKEATASARALESYLGGATGMSLIPVFHTYDSLTHLANYSQVSPAEQQSILQRVTVNQEKSKRWADAAPMNQLHKFYLVEAEKHRVLSQPAAALEFYDLAIKGAKQNEYIQEEALANELAAKFYLEWDKEKIATVYMQEAYYCYSRWGAKAKVADLEQRYPQLLLPILEPPRTNDLLQQTIARGTITSAHTSSSISDALDLKTLLKASQVISSEIELDKLLMTLLEIMIGNAGANKCVLLLKQGIDLKVVGLIEFGKSPQLLPSISLESSSDIPITLVNNVRRTGKPIILGDARIHPQFTEDSYIQKHQPKSVLCSPILNQGQLVGVLYLENHLTIGAFTSDRVEVLNLICAQAAISLENARLYQTAQQTLTDLKEAQLQIVQSEKMSALGNLVAGIAHEINNPVNFLSGNIDPALDYINDLFDLLNIIHEKYPNLDPEVQGKIEEIELDYIRADLPELIDSMREGVKRINEISNSLRTFSRADSDRPVACNINSGLDSTLMLLKHRLKADETRPEIKVIKHYSDLPIIVCYAGQLNQVFMNLLSNAIDALEESNQGCNYADINHQIIIKTELSSDQQQVIIRIQDNGVGMSEALQAKIFEYLFTTKAVGKGTGLGLAIARQIIVEKHSGTLAVNSTLGQGTEFTISIPSYPKSESEQG
>NC_019693.1|WP_015147968.1|2009000_2009939_+|hypothetical-protein
MSRDDHKYRLVTRSDFDGLVCAVLLKELNLIDEIKFVHPKDMQDGKIEISDRDITTNLPYVETAHLVFDHHESETLRNPEAKDNYIIDPKAPSAARVVYNYFGGPEKLTNISTEMMEAVDKSDSAQFERSEILDPQGWVLLSFLMDARTGLGRFKEFRISNYQLMMELIDYCRNHSIEEILQLPDVKERSDLYFEHQDKFNQQLKDCAKVYNSLVVLDLRNEETIYAGNRFTIYALYPTCNISMHILWGLKQQNTVFAVGKSILNRSSNLNIGALMLEYGGGGHANAGTCQVENEKAEQEKQALIDRITAQG
>NC_019693.1|WP_015147969.1|2010022_2010352_-|hypothetical-protein
MLNAQQNSKGNFMVVDLAEGILVGSLMPKDNLPALRSGFAGYPANPRWNVIKYRAWKMGRQLRQSLDEGDLVVRSTDFMLVPAQESSATQIGKVKQPSDRFLSTPMVLA
>NC_019693.1|WP_015147970.1|2010958_2011807_-|SDR-family-NAD(P)-dependent-oxidoreductase
MNIQDKTALITGASRGIGRAIALELAHQGMKRIIIVARDRDKLAEVEAEIAAIGVEVVSLPLDLTRPVEVDIAIAKAWKHHGPIHLLVNCAGVAHQTPFLQSKFPKIQEELSLNIMGMYEITRMVAKRMAARQEGTIVNVSSLMGKVAAPTMSTYSATKFAILGFTQALRGELAEHNIKVVALLPTLTDTDMAKNLELFRWVVPMTPQQVAKALISGLNKDSSEILVGWQSHLAVLCQRIAPWLLDKMLLMASPLSGSLVKRNYRRNQASDRLLREAAAASR
>NC_019693.1|WP_015147971.1|2012891_2013155_+|DUF4212-domain-containing-protein
MNNENRHAYWRANKALIRNLLIVWGIVSIGCSILFVQPLNLIRIGELPFGFWMAQQGSIYIFVVLIFIYAVQMDKLDRKYNDNNRRD
>NC_019693.1|WP_015147972.1|2013158_2014850_+|cation-acetate-symporter
MSVEAWTTILVILSFIMYTYIGWRSRVRDSKGFFVAGQGIPAIANGAATAADWMSAASFISMAGLISVLGYDGSIYLMGWTGGYVLLALLLAPYLRKFGKYTVPDFVGDRYYSTTARLVAVVAAIFISLTYVAGQMRGVGIVFSRFLQVDINQGVIIGMIIVGFFAVLGGMKGITWTQVAQYSVLIVAYLIPAVALSFQLTGNPFPQLAFTFSDIVPQLNQIQLDLGFAEYTQPFTEKSMLDVLFITIALMVGTAGLPHVIVRFYTVTNIRAARYSAGWALLFIAILYTTAPALSTFARYNLINNLNGQTIEQVSQLDWATKWEQTGLLTFEDKNTDGVLELTPDPDTNEIDIDRDIIVLSTPEVANLAPWVVALVAAGGLAAALSTASGLLLVISSSVAHDIYYRLINPRASETKRVMVGRIMVGFAIAIAGYFGINPPGFVAQVVAFAFGLAAASFFPVIILGIFDGRTNREGAIAGMVAGLAFTAYYIIAVNFYGMEPWLFGISAEGIGTIGMMINFAVTLIVSRLTPPPPLEIQTMLENLRSPGNEPLALEEMDEEHLD
>NC_019693.1|WP_015147973.1|2015248_2016760_+|WD40-repeat-domain-containing-protein
MDWTTPLKFQQADFIKRLNHKRAALLHCQSPGLHGEQVTIAGERFRAIHSACEQRLSSTQSPTPISELFRDRLRHQLGVEAVATYLDHRVTRIDPSHPPQSPNPGDFTLKANPAIALSVQAICSSTSPLVWEIELSQIKQQAAIIFVLIPEPIPSSRSEYHPILAGFLPTHLIAMSEGRARLCLDDLFYMGGLNLYLESLSSIPVSTEWLRILTGSSNYVYPVAISADGGLVASSSYDGTIKLWKLRDREITQALCGHSWSFYPIAGGQAGQSLASGSTEKKLNLWQRGRGDFIRTLAGHTSGVSAIAISEDSKILVSGGYDGTIDIWDLLQGQRLRTLSGHSGTVRPISLSPDGTILATGGIDKKLNLWNLQTGALIRSFNIDTDVAISLAISPNGQLLVSGSQDGTIKIWNLESGRLIRAIAAHSGIVRGVTLSHDGKTLASGSLEKTIKLWSVDTGDLLRTLTGHPDPTITFAIDSEGPTLDTSLLRHYQPGWEEPRQWQ
>NC_019693.1|WP_044194740.1|2016897_2017704_-|TPM-domain-containing-protein
MQSTFPKRLLISVAAFFLAVSAWAIAPISAQAYDNPELLPEIQTPIIDLANSLTSIQEENLVQELENFEAETGWKLRVLTQYDRTPGRAVKDYWDLNDKSVLLIADPRGGNLLGFNVGDELYPLLPRTFWIELQTRYGNQFFVRDNGEDQAILSALNSVENCLRQGGCLVVPGLPREQWILTLITSTVGGVIFGFAAHPRKDRQAFSWQWALMFSPLWGILFIAFGLGPVISRTSDFLPLLRNILGFLLGALVAYLTPILNGSSTSET
>NC_019693.1|WP_015147975.1|2018037_2018403_-|DUF1823-family-protein
MSELPPLNFDTIWDILNDKIDDLTVNRLVWHCLGYRYEEMSQTWNTDAVDPLWRDEYPEPPDFIASRPATVKLTRSIPKENKQLLKEKLGFSGYKVGELIPRLTRRATMANWLLSYLDSQP
>NC_019693.1|WP_015147976.1|2018514_2023698_-|hypothetical-protein
MTQLDPPIECSLYNDRSLQTLARAIALSQGNFSLILVRCNYGTLQRSMLQRLESLCQEISEEGRSVHSMVLPKTVSTLYSAVRDSVDHKQPLAVMIFGLDCTNGLEQLLVSANQVRDEFRNSFPFPLIWWVTEEVLACLIRFAPDFKSWAATSIKFEMETDSLLDLLHQEAGSLIPQLLARGAKEGGYEWCIPSPLESNRRKELESAIKDCFNRGVTLRRELCASVQFVLGRDEFCRDRLDTAEAHYHESLTLWQHIGSGSPLTDPAQPAPEITPLMVSSPDLERLGLLWFHLGLLYCRKAELYQSQSQQHLMEAESYLDRALTLFESGGRLDVVAQLSPLLGEVLARLQRWDRLQVQVEKTVDLHENHPVQLARDYGFMAEVALARFEWSLSKEYAQKAIAALALAPVTERQEQGLYLYLLARATVPELSPEDATSAPRKLKDSAPSWYQQSQAAIEILNFAQQVSKPERDPQLYISILKLLRSLYFEHREYVEAFRLKQEQRSIETLYGFRAFVGAGLLQPQTKNHPQPLNQSALSGLAPKYSEFLGLPQEIAAAGRQSHIECLLERMTRADKKLTILYGDSGVGKSSLVNAGFVPALAGRAIGDRLALPVVLRSYTDWIATLSKRLNETISQTLGIPLEPNPEWAELDGDLEPGESLTGQNSARPSPVQAALSMLRSNVNRNLLTVIVFDQFEEFFFVHKTQESRHEFYRFLQICLDIPFVKVILSLRTDFLHYLLDCERLCYLDAINNDILSKEIRYQLSDFSAAQAVEVIQRLTERSQFYLETELIEALVRDLANETGQVRPIELQLVGAQLQDDEEKITTLEQYQKLGDRPKEILIARSLVQVIRDCGPDNEKPAWEVLYRLTNQNNTRPLRTQEELAASGEVTPAQLDLILTILEGAGLVFIHREESGDRYQLVHDYLVHPVRQKYESAFGPEARLVKAEEAKKMTQAQLEKSNKKLKRIGGFLGVLVGLLAVTSVFALAQKEQASIGVENAQITAISASSEALYVSDREFDALVESLRAWRKLSIAKNPDSETKLRVAAALQQAVYGVRERNRLEEHGAEVWSVAFSPDGQLLASGSNDTQVLLWNRNGSLHKKLVDYSLDVTGVSHADEVTSVAFSPDGDFIASTSRDRTVKLWKRDGSLYKTLNGHTNSIYSASFSPDSQFLATASHDQTVKLWRVSDGSLVRTFNGHTDSVNWVMFSPDGQTLASASDDKTVKLWTLDGTVRKTLRVHTDWVTALAFSPDGRHLVSAGVDHMISVTNLEEDTTQTWKAHDDIVFSLSFSPDGRWFASAGDDNAIKIWKLDGTAIKTLKGHSGRVTSVNFSPDGMTLASASWDKTIRLWTLKDTFLKVLAGEVGHKGRVSSISLSPTGKQLASASWDKTVKIWSLEPGRTTEAVTTLQAPDGHGDRVFGVSFSPDGRAIASVSQDCTVKIWNASNGTLLKTLVDPNLTSDPSKHSDCPVESSHSDRIYSVSFSPDGQLIASGSRDKTVKIWRIDGTLLKVLEGHSERVNSVAFSPDGRLIASGSDDKMVKLWSKEGELLQTLSGRYPHQSYVTSVTFSPDGQRVASASWDNTVKIWNLDGTLEKTLLQGYSDSVESVRFSPDGRLLVSASWDGTVKLWSLKDGTLLKTLQGHTSGVLDVEFSPDGEIIASAGDDNTVILWNLDLDDLTRRACTWLHDYFKYSKNISEGDRALCEEAIKEQRFPKSSVPYLQRWSRSR
>NC_019693.1|WP_044196727.1|2024836_2026219_-|KAP-family-P-loop-domain-containing-protein
MKLDLPRFYKACNPSKVLDMADEEDREYYIDFSSVRGGNIIRELGRTISLLSGDEPTCQLFTGHIGCGKSTELFRLKKDLEAEGYHVVYFESSHDLDMADVDITEILLSIARQVSESLEKINLCVEPKRGFRDLLKGAADLLQTPIELSGEASLPGIGTFSASSDGELGFSLPGGIGSITAKARHSPRLRQQLRQYLEPRTNNILEAINSELLNPATEILNQRGKKGLVAIVDNLDRVDSVRKPSGRTQPEYLFVDRGEQLRKLNCHVVYTIPLSLIFSNDLGRLSSRFGVKPKVLPMVPVRERDGSVYAEGMKLLRNMVLARAFPHIPASEREDLIASVFDCSETLNRLCSVSGGHVRNLLGLLYSCLQLQDPPFSRHCLENVIKEYRDDLIAAITDDEWELLFQALEQKHVQGDEDYQLLLRSMFLFEYRDRDGRWYWINPALAEAPKFKEWMSEYPA

Crispr_ID: NC_019693_22

• CRISPR_ID: NC_019693_22
• CRISPR_location: 2715547-2715644
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_22

Consensus_repeat	Method
AACTCCACCTCCGGTCCCCTCCCCT	CRISPRCasFinder

spacers of NC_019693_22

>22.1|2715572|48|NC_019693|CRISPRCasFinder
GTGTCTTGGTCCGGGTTAGGGTCTGACAACGGTAGGTTTTTTCCCGTG

CRISPR arrays and Neighbor proteins around NC_019693_22

CRISPR arrays

The CRISPR arrays of NC_019693_22

>merge|NC_019693|22|2715547-2715644|CRISPRCasFinder
AACTCCACCTCCGGTCCCCTCCCCTGTGTCTTGGTCCGGGTTAGGGTCTGACAACGGTAGGTTTTTTCCCGTGAACTGCACCTCCGGTCCCCTCCCCT

>NC_019693|22|22|2715547-2715644|CRISPRCasFinder
AACTCCACCTCCGGTCCCCTCCCCT	GTGTCTTGGTCCGGGTTAGGGTCTGACAACGGTAGGTTTTTTCCCGTG
AACTGCACCTCCGGTCCCCTCCCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015148526.1|2723764_2724211_-|hypothetical-protein	unknown	unknown	gnl|CDD|224845
NC_019693.1|WP_015148517.1|2714464_2715499_+|bifunctional-sugar-kinase/adenylyltransferase	unknown	unknown	gnl|CDD|274029
NC_019693.1|WP_015148521.1|2718083_2719475_+|asparagine--tRNA-ligase	unknown	unknown	gnl|CDD|235176
NC_019693.1|WP_015148514.1|2706323_2712041_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NC_019693.1|WP_015148522.1|2719572_2721216_-|hypothetical-protein	unknown	unknown	gnl|CDD|223021
NC_019693.1|WP_044196923.1|2717076_2717370_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148518.1|2716526_2716976_+|anti-sigma-regulatory-factor	unknown	unknown	gnl|CDD|225083
NC_019693.1|WP_015148513.1|2700343_2705785_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NC_019693.1|WP_015148512.1|2694697_2700010_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NC_019693.1|WP_044196925.1|2717670_2718006_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148510.1|2691375_2692347_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|177093
NC_019693.1|WP_015148516.1|2713671_2714232_+|response-regulator	unknown	unknown	gnl|CDD|381085
NC_019693.1|WP_015148525.1|2722883_2723615_-|LPS-export-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224060
NC_019693.1|WP_015148511.1|2693095_2694598_+|alanine:cation-symporter-family-protein	unknown	unknown	gnl|CDD|376500
NC_019693.1|WP_015148509.1|2690231_2691149_-|NAD(+)-kinase	unknown	unknown	gnl|CDD|179456
NC_019693.1|WP_015148523.1|2721491_2722604_-|YjgP/YjgQ-family-permease	unknown	unknown	gnl|CDD|367632
NC_019693.1|WP_015148528.1|2727741_2728137_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823812.1|2724807_2727351_+|hypothetical-protein	unknown	unknown	gnl|CDD|197594
NC_019693.1|WP_044196921.1|2688780_2689857_-|heat-inducible-transcriptional-repressor-HrcA	unknown	unknown	gnl|CDD|234621
NC_019693.1|WP_015148515.1|2712384_2713317_-|lipoyl-synthase	unknown	unknown	gnl|CDD|237261

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015148526.1|2723764_2724211_-|hypothetical-protein	gnl|CDD|224845	COG1934, COG1934, Uncharacterized protein conserved in bacteria [Function unknown].	9.27006e-27
NC_019693.1|WP_015148517.1|2714464_2715499_+|bifunctional-sugar-kinase/adenylyltransferase	gnl|CDD|274029	TIGR02198, Uncharacterized_sugar_kinase_BU060, rfaE bifunctional protein, domain I. RfaE is a protein involved in the biosynthesis of ADP-L-glycero-D-manno-heptose, a precursor for LPS inner core biosynthesis. RfaE is a bifunctional protein in E. coli, and separate proteins in some other genome. The longer, N-terminal domain I (this family) is suggested to act in D-glycero-D-manno-heptose 1-phosphate biosynthesis, while domain II (TIGR02199) adds ADP to yield ADP-D-glycero-D-manno-heptose. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	1.88825e-123
NC_019693.1|WP_015148521.1|2718083_2719475_+|asparagine--tRNA-ligase	gnl|CDD|235176	PRK03932, asnC, asparaginyl-tRNA synthetase; Validated.	0
NC_019693.1|WP_015148514.1|2706323_2712041_-|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	0
NC_019693.1|WP_015148522.1|2719572_2721216_-|hypothetical-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	2.88945e-08
NC_019693.1|WP_015148518.1|2716526_2716976_+|anti-sigma-regulatory-factor	gnl|CDD|225083	COG2172, RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms].	2.70052e-25
NC_019693.1|WP_015148513.1|2700343_2705785_-|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	0
NC_019693.1|WP_015148512.1|2694697_2700010_-|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	0
NC_019693.1|WP_015148510.1|2691375_2692347_-|SDR-family-oxidoreductase	gnl|CDD|177093	CHL00194, ycf39, Ycf39; Provisional.	0
NC_019693.1|WP_015148516.1|2713671_2714232_+|response-regulator	gnl|CDD|381085	cd00156, REC, phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs). Two-component systems (TCSs) involving a sensor and a response regulator are used by bacteria to adapt to changing environments. Processes regulated by two-component systems in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Response regulators (RRs) share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. Response regulators regulate transcription, post-transcription or post-translation, or have functions such as methylesterases, adenylate or diguanylate cyclase, c-di-GMP-specific phosphodiesterases, histidine kinases, serine/threonine protein kinases, and protein phosphatases, depending on their output domains. The function of some output domains are still unknown. TCSs are found in all three domains of life - bacteria, archaea, and eukaryotes, however, the presence and abundance of particular RRs vary between the lineages. Archaea encode very few RRs with DNA-binding output domains; most are stand-alone REC domains. Among eukaryotes, TCSs are found primarily in protozoa, fungi, algae, and green plants. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays.	4.75845e-22
NC_019693.1|WP_015148525.1|2722883_2723615_-|LPS-export-ABC-transporter-ATP-binding-protein	gnl|CDD|224060	COG1137, YhbG, ABC-type (unclassified) transport system, ATPase component [General function prediction only].	3.65169e-142
NC_019693.1|WP_015148511.1|2693095_2694598_+|alanine:cation-symporter-family-protein	gnl|CDD|376500	pfam01235, Na_Ala_symp, Sodium:alanine symporter family.	3.001e-161
NC_019693.1|WP_015148509.1|2690231_2691149_-|NAD(+)-kinase	gnl|CDD|179456	PRK02649, ppnK, NAD(+) kinase.	0
NC_019693.1|WP_015148523.1|2721491_2722604_-|YjgP/YjgQ-family-permease	gnl|CDD|367632	pfam03739, YjgP_YjgQ, Predicted permease YjgP/YjgQ family. Members of this family are predicted integral membrane proteins of unknown function. They are about 350 amino acids long and contain about 6 transmembrane regions. They are predicted to be permeases although there is no verification of this.	2.25505e-79
NC_019693.1|WP_156823812.1|2724807_2727351_+|hypothetical-protein	gnl|CDD|197594	smart00237, Calx_beta, Domains in Na-Ca exchangers and integrin-beta4. Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins).	1.42262e-16
NC_019693.1|WP_044196921.1|2688780_2689857_-|heat-inducible-transcriptional-repressor-HrcA	gnl|CDD|234621	PRK00082, hrcA, heat-inducible transcription repressor; Provisional.	7.91888e-135
NC_019693.1|WP_015148515.1|2712384_2713317_-|lipoyl-synthase	gnl|CDD|237261	PRK12928, PRK12928, lipoyl synthase; Provisional.	0

Protein sequences

>NC_019693.1|WP_015148517.1|2714464_2715499_+|bifunctional-sugar-kinase/adenylyltransferase
MAIESHFADRLREGARRSLELIDRFSTARVLVIGDLTLDEFLTGQVERISREAPVLILRHESTRQVPGGGANAVYNLAKMGANVKVAGLIGKDEQGKALCRIFEEAGIDTGGIFLDGDRPTVTKTRISGHARQSVTQQVVRVDRKSDELPRLDLQEQLADYIRAQLPTVDAVVCSDYGDGALTPLVIEAALGHGLTVVDAQTDLHRYAGATIFTPNVPEAEQAVGYSITTPPSVTQASRDLLTLTQAEQMLITRGDEGMTLCDRAGMEHHIPPFNRTDVFDVTGAGDTVVSALTLGLCAGGSYWEAAVLGNLAASIVVRQFGTATTTQGEMKEALALLLSEETV
>NC_019693.1|WP_015148516.1|2713671_2714232_+|response-regulator
MASHKILVIDDSAVIRRMVRDMLPAGNFEVLEAKDGEQGLKQIREERPNLIMLDFLLPKVSGWEVFQQLDKISKTEGKMTPLVLMSGRKEEVAEKIAEPFEYFEFIEKPFEKKSLIEAIKISMAKAKKWQPAGAPAAAAAPAGAAGGASAAEIQALKQQMAKMQAEINALKKQMTQVVTLIKTKLK
>NC_019693.1|WP_015148515.1|2712384_2713317_-|lipoyl-synthase
MSAQTNPTNPTAATPFRNEIEAMPDWLRRRGIGKASELSQVQRIIKQRQIHTICEEGRCPNRGECYGNQTATFLLMGPTCTRACGFCQVDKGHAPMPLDPQEPQKVAEAVQLLGLRYVVLTSVARDDLADGGAGWFVATMDAIRDRTPETQIEVLTADFWGGQGAELERLQRERIATVVAAKPACYNHNIETVRRLQGRVRRGAKLERSLGVLKIVKELDSTIPTKSGLMLGHGETQDEIIEAMAELRAVDCDRLTLGQYMRPSLEHLPVQKYWTPEEFEQLGSVAREMGFSHVRSGPLVRSSYHAGEAE
>NC_019693.1|WP_015148514.1|2706323_2712041_-|AAA-family-ATPase
MLTIPGITVQTQIYESANSLVYRGIRESDHQRIILKILKENYPTPYELARYRTEYQITQSLNVPGVVKVYDLQTYQNTLVMFLEDFGAESLKHWINQRPFSLEEFFAIAIAATEALGQIHAANLIHKDINPSNILFNPTTGQIKIIDFGISTQLTRENTTLQSPNGLEGTLPYLSPEQTGRMNRCLDYRTDFYSFGVTFYELLTHRLPFETTDALELVHCHIAKQPIPPTDIDAKIPPVLSEIVLKLMAKTAEDRYQNAYGLKADLEECLRQYNANNLLDFPLGRHDVSNKFQLPQKLYGRESEIQNLLSAFSESSTASQLMLIAGYSGIGKSALVQELYKPITEKRGYFISGKFDQLQRNIPYSAIVSAFQGLVKQLLTESKAQLNQWRNNLLAAVGVNGRVIVEVIPEIELIIGPQPEIPELGPNESQNRFNLVFQNFIKVFTQPQHPLALFIDDLQWADGASLKLMQLLMAGRSPGLFLIGAYRDNEVSAAHPLMLTLDEIAKTGAVIQRISLAPLDLETIAQLIGDTLNSDLQTVRSLAELVQAKTGGNPFFMNEFLKSLYTEKLVDFDRQTRQWQWDLEPIQARSFTDNVVELMVGKIQKLPEETQELLKIAACIGNEFDLESLGLILSKKSEELANHLYAAVAENLLNPLGNIGDIALVVAEAEFLSMALPRNSVKSLPYKFVHDRVQQAAYFLIEDSQKSQFHQKIGQIMLENTPEDKREEKIFDIVNQLNLGSALIAEHSAQPELAQLNLMAGKKAKLSTAYQPALNYLQIGIEQLPPNSWQQQYPLTLSLYEEAAEVAYLSGDLALMDQFVATVLSQAKTVLDKVKVYEVKILAYNAQGLFAEAIAIGLEVLNLLGIKLPKQANKLDVLRGLLATKLTIGRRAIASFIDLPTMTDPSSQAAMRIIAKISSAAYMAEPFLLPLIVFKQVSLSLKWGNASESAFAYSSYGLILCSVAEDFPGSSQFGQLALQLLYKLNAREVEARTQYVIYHFIQHWIAPVKEVLNPLRQAYAVGLETGDLEFGTYAALQYSGYALLSGSELVQLESEMATYTQVMEEMGQERNLAMQSLYHQAVLNLIEEGENPGILMGRALDEQVMLSMIKSRNDRTAISSLYFLKLMLSYLFNERENALAFAEVAEEYLDGITAILLVAHFYFYDSLARLLVATDASPTQKKALLQKASRNQKKIKKWMHYAPQNNSQKYWLVEAELCRVQGQDAKAMDYYDKAINLAKQNEYIHEAAIAYELAAKFYLSRGKELTAKAYMQEARYCYQRWGAVAKVKHLEENYGDLLTTTHGKVSSSQMANAQTTTGSGSNLDIATVTKSYQAISGEIMLDKLLSSLMKIILENAGAQRGYLILCHQGELRIEAESHIDEEQITVLQARLITDCSLISEAIVNYVARSQEAVVLNDATQEGNFTSDAYIQTHQPKSILCVPLINQGTLLSLIYLENNLTTGAFTPERVELLKLLSGQAAISIQNAKLYTEVRENESRLNQFLEAMPVGVGILDASGKPYYINRIAQELLGKGVMADTKDISEVYQLYKAGTEEEYILTELPLVRALQGETSIADDIEIHQNGKIIPLEGVGQPIYDSQGNIAYAITAFQDITERKRAEAERERFTNELFQLNQAYERFVPNQFLQFLEKSSIVDVELGDQVQLEMSVLFSDIRDFTTLSESMTPEDNFKFINAYLSRMEPAITEHSGFIDKYIGDAIMALFSGEADNAVKAAISMLHRLGDYNQHRIQQGFAPIKNGIGINTGLLMLGTVGGQNRMDGTVISDAVNLASRVEGLTKNYGVALLITDQTYARLMQRESYAIRRIEQVKVKGKSEAVTVYEVFDADSEEMKAGKLATLGRFTEALSLYDAGKFLEAAQLFGDCVTQNPGDRVAQIYGDRAQQKHHP
>NC_019693.1|WP_015148513.1|2700343_2705785_-|AAA-family-ATPase
MLTLPGVAVQVQIYESSNSLLYRGIREQDNQSIILKLLKENYPTAQELIRYRTEYEITKSLNVPGVVQVYDLQKYQNRLVMFIEDFGGESLSYWMQHRQFTLAEFLQIAIETTEALAQIQAANIIHKDINPGNIVFNPTTGQIKIIDFGISTQLTGENTTLNNPNSLEGTLAYLSPEQTGRMNRCVDYRSDFYSLGVTFYELLTHRLPFESTDPLELIHCHIAKQPIPPHLRLENLDAEGKFSEWGIKRIPPVLSEIILKLMAKTGEERYQSAYGLKADLEFCLQQLQKTGQISPFPIALQDISDKFQLPQNLYGREAEIEALIAAFERARRQSQLMLIAGYSGMGKSALVQELYKPITAHRGYFISGKFDQYQRNIPYSALVRSLQQLIKHLLTESEAQLKQWQDKLLTALGVNGQVIVEVIPEIELIIGKQTPVPTLGPNESQNRFNLVFQKFIKVFTKPEHPLALFIDDLQWADGASLSLIQRLMAGAVPGLFLIGAYRDNEVSAGHPLELMVDEMTKNGAIIERISLSPLELATIAQLIADTLKSTAAAVMELAELVQFKTGGNPFFMNEFLKSLYTEGLLQFGTQVSESPDARFALPDFPETLGRVGVGWFWNLEQIKARDFTDNVVELMTGKIQKLPESTQLLVKLAACIGNEFDLNLLELVSQQSLKETVEDLKAAVAENLVRSQMNQGEIELILAEEDYSYCYLPRKEYPALIYQFVHDRIQQAAYFLIPDAERTRVHRDIGQILLENTPPNRREEKIFDMVNQFNFALELITESRQKYEWAELNLMAGEKAKLSAAYQPALTYLKVGIDLLEQDSWQQHYALTLSLYAKAAEVAYLNTDFELMDQMIEAVLSHAETVLDTVAVYEVKILAYNAQSQFNEAIAIGLKVLKLLGVKLPSHPHTGHVLWGLLQTKLAIGFKPVASLVDLPLMSAAYPKAAMSILGKITSSAYFAAPLMFPLIVFKNVTLSIKWGNSSESAYAYSSYGVILCGVVGQLQTGYQFGQLCLKVLSQLNARDVKARTEFVVGALIQHWIDPLNSVLKPLLNAYQMGLENGDLEYAAYAACHYCYNAFLSGQELVPLESQMATYATCIQEMGQVRVLNLQEVFHQGVLNLLGKSADPCVLQGTAFDETMMLPELESRNDRTAICYLYFNKLILSYLFEDIEQALTTANLCEPYLDGVTASPVVIYFYFYDSLIRLDIAGKSDALSVKMLLKKVSKNQKKLKKWARIAGMNNAHKFELVEAERYRVLGENHRATACYDSALDLAKKRDCLPETALIYERAAKFYFAQGKVLVAKAYLQEAYYCYQLWGAAAKVKQLKNLYDNLLTPENRKISDTKKTISASAADLLAHLDVSTMMKASQAIYGEIVLEKLLSSLMKIAIENAGAQRGCLILSHQGQLMIEAEGTIDGDRLTILQSIPLTESDLVSVAIVNYVARTQEAIVLNNATQEGDFTNDSYIQKNQTQSILCVPLIDGGKLVSIVYLENNRTTGAFIPERVEILKLLSGQAAISIQNAKLYSEVRNNEKHLAQLNQAYERFVPRQFLQVLNKASIVEVELGDQVQVEMSVLFSDIRDFTTLSESMTPEENFKFINSYLSRMEPAIAEHSGFIDKYIGDAIMALFSGEADNAVKAGISMLHRLVDYNKHRENCNFAPIKNGIGINTGSLMLGTVGGENRMDGTVISDAVNLASRVEGLTKNYGVSLLITEQTYSQLIHRDRYAIRRIDRVQVKGKSEEVTVYEVFDADSPDIKAGKLATLDRFTEALSLFDDEDFLGSARLLAYCLNQNPGDQVAHIYFEQCQRRFTGLR
>NC_019693.1|WP_015148512.1|2694697_2700010_-|AAA-family-ATPase
MLTLPGVTVHTEIYESDNSIVYRGIWDADSQPIILKVLKENYPTPQELARYRTEYQITQSLNVPGVVKVYDLQKYQNTLVMFVEDFGGESLKHWLSQRPFNLEEFLHLAVAITEALGQIHAANIIHKDINPSNIVFNPITGQVKIIDFGISTQLTRENTTLKNPNILEGTLAYLSPEQTGRMNRCIDYRSDFYSLGVTFYELLTRRLPFETTDPLELVHCHIAKQPIPATDIDVRIPPVLSEIILKLMAKTAEDRYQNAYGLKADLEECLRQQQTNSLLNFSLGRYDVSDKFKLPQKLYGRESEIQSLLAAFAGSSIQSQLMLIGGYSGIGKSALVQELYKPITERRGYFISGKFDQYQRNIPYSAIVSAFQGLVKQLLTESETQLNQWRENLLGAVGVNGRVIVEVIPEIELIIGQQPEVPELGPNESQNRFNLVFQNFIKVFTQPEHPLALFIDDLQWADGASLKLMQLLMAGRSPGLFLIGAYRDNEVSAAHPLMLTLDEIAKTGAVVQRITLAPLDLETIAQLIGDTLNGDVQTVQPLAELVQGKTGGNPFFMNEFLKSLYTEELVNFDRPTLRWQWDLEQIQARGFTDNVVELMVDKIHKLPEETEELLQLAACTGNQFDLKILGLICEKSLAEMVTNLQSAVAENLVMPLGNLGELALAIAESEFLTHDPTQTKLKSLQYKFGHDRIQQAAYSLIDELQIPYLHRKIGEVILQNTPKHKQEEKIFDIVNQLNFGIGLMTEQVEKNELAELNLIAGKKAKLSTAYQPALNYLQQGIELLGNHSWQDQYALTLSLYEEATEVAYLKTDFALMEQWVEIVVKQAKTVLDKVKVYEVKIQAGVSQSKFNEALDIGLEVLSLFGIKLPRQPKKIDVFLGLIQNKLTIGLRPIASLGDLPPMTQPDIQAIMGILSKLNTAIYFSAPLLFPLAVFQQVNLSIKWGNTSESAYAYSCYGLILCGLGDIDSGYQFGQLALNFLKQLNTKKVKPRTDYLVHSFIKHWKDPVQEMLTPLLEAYTVGLETGDLEFAAYSAFHYCYYSVLIGAELTQLESDMEIYAQVIEDTGQERTTDGHRIFYQTVLNLLGQAENSCDLIGKAFDEQVRLPILQSRKDRSTIFCIYFNKLILCVLFGEFHQAIANADLAQEYIDAVPATLLLSHVYFYDSLARLARAPEASRSQKNSWIRTVFRNQKKIKKWADYAPKNNSHKYWLVEAELCRVQCKDVQAMNYYDKAIILAQENNYLHEAAIAYELAAKFYLSNGKEKELTAIAYMQQARYNYQLWGADAKVKDLETRYGEFFIARERVSTNSAINSVVSTTGSSSSLDIATVMKASQAISGEVLLEKLLSSLMKILIENAGAQRGYLILSIQGELLIEAAGEIEEERVTVLQSIPVANCQTLCESIVNYVARTQETVVLNDATSSGNFTSDSYIQQAQPKSILCVPLIDRGNLVSIVYFENNSTTGAFTPERVEVLQLLSGQVAISIENARLYQTLEEKVKDRTAQLANANAEITMLNEQLKAENIRMGAELDVTQRLQKMLLPSQSELDGIEGLDIAGFMEPADEVGGDYYDVLKSGDRIKIAIGDVTGHGLQSGVVMMMAQTAVRTLLEGDFTDPVQFLDVINRTIYKNVQRMNADKNMTLVLLDYQQGKLTLSGQHEEAIVMRANGTVECIDTVDLGFPIGLIDEISEFVNTTEIHLNSGDVVVLYTDGITEAVDSNLVQYGLEPMIASIRHRLQGNAREICQAVIEDVRRHIGEQKIYDDLTLIVLKQK
>NC_019693.1|WP_015148511.1|2693095_2694598_+|alanine:cation-symporter-family-protein
MKKRWISLIILFLLALPIAAVAQEAEEAAPTGFLPTLNAVFTQLVEWMSAVLFFDFGLGVPLIVLWLIGGAVFFTIRMGFINFRAFKHAFFVIQGHYDDPAEAGEVSHFQALAAALSATVGLGNIAGVAIAISIGGPGAMFWMTVAALFGMTSKFVECTLAQKYRVVLPDGRIAGGPMYYLSRGLAEKGMGQLGNIMASLFAILCIGAAFGGGNMFQANQSFVAVSGLFPGLPNWVYGLVLAFLVSLVIIGGIRRIGNVAGALVPAMCTIYIAASLWIILMNLPEIPAAFGRIFTEAFVPQAAYGGFIGVIVQGFRRSAFSNEAGVGSAAIAHAAARTEEPVREGIVALLEPFIDTVIICNMTALVVIITGEYANPNTSPGVETTSAAFASVISWFPIVLAVAVLLFAFSTMISWSYYGERAWTYLFGESSMIIYRVIYVVCVFLGTVLNLGAILDFSDMMFFAMAFPNMLGGFLLADKVREDLDSYMLRLNSGEMPVYK
>NC_019693.1|WP_015148510.1|2691375_2692347_-|SDR-family-oxidoreductase
MSLLVVGATGTLGRQVARRALDEGYQVRCLVRSFKKAAFLKEWGAELVRADLCDPETLPVALEGVTAIIDAATNRPTDSLSIKQVDWDGKVALIQAAKKAGVERYIFFSILDADQYPEVPLMEIKRCTEVYLAESGLDYTILQLAGFMQGLISQYAIPILDNQAVWVTNQTAPIAYMDTQDIAKFAVAALSVPETSKSVFPVVGTRPWTPQEIIELCERLSGEKAKVTRMPFGVLRAFRRVVRFFQWGWNVADRLAFAEVLASEKPLTANMDEVYPVFGLDPKDTTTVESYLREYFSRILKKLKELDYEQSKTKKQSKRRVPF
>NC_019693.1|WP_015148509.1|2690231_2691149_-|NAD(+)-kinase
MPKAGIIYNDIKPIACRAAEEWRDKLIGLGWEVALATGMGGILGYSDLDKPVCHTTVEQLTPPGFDAEMSFAVVLGGDGTVLSAFRQVASCGIPLLTVNTGHMGFLTETYLNQLPQAIEQVLAGNYQLEERTMVTVQAIRDDIVVWEALCLNEMVLHREPLTCMCHFEIQVGRHAPVDIAADGVIISTPTGSTAYGLSAGGPVITPDVPVLQLVPICPHSLASRALVFANTEPVTIFPANTNRLVMVVDGNAGCYVLPEDQVRIQRSPYSAKFIRINPPEFFHVLREKLGWGLPHIAKPTSVELP
>NC_019693.1|WP_044196921.1|2688780_2689857_-|heat-inducible-transcriptional-repressor-HrcA
MQMNLNERQQYVLWATVRHYIATAEPVGSKTLVDEYNLSVSPATIRNAMGWLEKAGLLYQPHTSAGRIPSDSGYRIYVDKLIKPDDGISRQVEQALSDRLKLENWAFEAVLRGASQILAALSGYIALITMPQTHTACLRHLQLIQIEPRKIMIVVVIDNYQTQSAVMELPESPEDSLVDAEVVDRELQILSNFLNHHLRGQTLAQLSALDWTELGREFERYAEVLSHWLQDLAVRAQTPGKTQILISGVSEVLRQPEFCELTQVQTLIQLLEEEQDQLLPLIFEPPAPEGSGRRVQVRIGAENPLEPIRTCTLVSATYHRGTVPVGSVGVLGPTRMVYENAIAIVEAAADYLSEALSV
>NC_019693.1|WP_015148518.1|2716526_2716976_+|anti-sigma-regulatory-factor
MIAISPRPIERSWNTISFASTLYLCPILDLLLVDIPRQWQAEIRLGLQEALVNAAKHGNNLDPRKTVVVRFSAIADEYWWAIADQGKGFACACPCHVDPDEHLPHDEGECGRGLFILHQIFDQVNWDDNSRELKLCKQFNQSSRLPMLR
>NC_019693.1|WP_044196923.1|2717076_2717370_-|hypothetical-protein
MGLHSPLSDKLQEFSTLELAQALAERLTLTETDWHRLKSNRSVRAKEQAAAALVFLLKENPEEALLRLHQAVGWIDRSISAPPCPTHGDRPSKSSSQ
>NC_019693.1|WP_044196925.1|2717670_2718006_+|hypothetical-protein
MGEIERELQETERSLNHLKERIAQVQRDRQRQRELQNRRDDIRREVRQAKNINPSVIPELKQELKQIQTTLEAIGFNLESELFSFREPFWQALRFGGIGIIIGWLLRAWAN
>NC_019693.1|WP_015148521.1|2718083_2719475_+|asparagine--tRNA-ligase
MKQRIVEILRTGEPQTSVTIQGWVRTKRELKEFTFVEVNDGSSLANLQIVLNPDLPQYTEILKQLNTGASLEVSGILVESPAKGQRIELNASEVKLYGESDPETYPLQKKRHSFEFLRTIGHLRGRTNTFGAVFRVRNAAATAIHQFFQERGFLWVHTPIMTASDCEGAGEMLAVTSLNLQDIPRLENSNQVDYGKDFFGKPAYLTVSGQLEAEVMAMALSDVYTFGPTFRAENSNTSRHLAEFWMVEPEMAFCDLTGDMDLAEAFLKYIFKFVLEKCPEDMEFFNQRIDKTVLETANNIIDNQFERVTYTEAVALLKKADKKFEFPVEWGLDLQSEHERYLAEELFKKPAIVTDYPVEIKAFYMRLNDDNKTVAAMDILAPKIGEIIGGSQREERLDILQRRLEQQGLSIEDYWWYLDLRRYGSVPHAGFGLGFERLVQFMTGMSNIRDVIPFPRAPLSIDF
>NC_019693.1|WP_015148522.1|2719572_2721216_-|hypothetical-protein
MSHSKPTSSSVRNIRAKLRNYTRPFVWGSVLILGLLTLLIWEFSNNPEQFYLSSLEDDEEYELDNEPEGWTGISPEDSAIAAEIDSSAVLLNDLNQMQPPPPLPLPTPINSNRRSPSTRSQPNRTQSSSNTSLPGVEDPNQNWQDLYKLPELSILPSSNEAASEALPELSVLGVPTPPANSNGTPPPPGNSLGLYSGNGNNLAAPDLTQLPVSPLQSAMDRLYSPNNSTSGDRNPDNPEASQGQESTPQEESNQGGSAENRRNPTQNPANSGSQTSPNSPRNTPQPAQTPNGTPQNGPNPSANPIPPGPNNPYGTPLNSPSPYGNSPQLTPTPNSTPENLRNSSGVQESLSNQSSGDPNQPITPRLPGEMSPNYNLDYSEDYNNPNNYQPLPGPQQVPNSNPTNAYEYLLRLRGEQVPVAPTAPTAAPQTPSNLGTATDLSPNSSVYQVPTTNPVGNPSSVSPGVQPLNQTNNLPSPSSLNQPTNVPTYQPLNPPSVQSPQQDNSSLNLNRDTPGVQPIQPIQTFSVPNAIPGRHIGGGNINTFSNP
>NC_019693.1|WP_015148523.1|2721491_2722604_-|YjgP/YjgQ-family-permease
MDRYIALELIGPFLFGVGSFSSVGVAIGTLFDLVRRVTERGLPIEIAVQVFLLKLPDFIVLAFPMSVLLATLMGYSRMSADSEIVALRSCGVSIYRLVVPAIALSFCVTGLTFAFNELIVPAANYEATITLQRAMNQERPSFQDRNIIYTEFDRVTQEDGNRVTVMKRLFYAEEFDGDRMKILTILDRSQTGVNQIISAESAIWNPKENSWDFFNGTVYLIAPDGSYRNIVRFEHQELQLPRTPLDLASRGRDYGEMSIAQAKERLEIIRHGGSEKNIQELEVRIQQKYALPFVCVLFGLVGSTLGLGPRRASKATSFGISIIIIFGYYLTAFLANALGQLAILSPFMAAWLPMALGLAIGGFLLVRASR
>NC_019693.1|WP_015148525.1|2722883_2723615_-|LPS-export-ABC-transporter-ATP-binding-protein
MKIWLENVHKSYGKRAVVNRVSLSVSQGEIVGLLGPNGAGKTTTFYMVTGLEKPTQGKVWLDNVDITPLSIQDRARLGIGYLAQEPSIFRNLTVQDNILLVLEQTKVPPWQWQQRLQTLLREFRLQIVADTKGKNVSGGERRRTEMARALAVRGEGPTFLLLDEPFAGVDPIAVSEMQQIVAKLRDRQMGILITDHNVRETLAITDRAYIMRDGQILAFGTPEELSTNPLVRQYYLGENFTLS
>NC_019693.1|WP_015148526.1|2723764_2724211_-|hypothetical-protein
MIPSVRLSSSHLLLRLGLALMMPIALSSVVAMPSYPQTPNAQQDNRALRVRSDMQESDSRTGIITARGNVRINYPARNMQGTAAQAQFFSREQRIVLSGNAYVIQDNNSIRGETITYLLDEGRFIALPEDNKQVESIYFLPDGTAPGL
>NC_019693.1|WP_156823812.1|2724807_2727351_+|hypothetical-protein
MPLEGFLDLNAFAVLVDETDYLTANPDVKIAVETGIFTSGLEHFQRHGKQEGRQPIAGYNTAYFLTDNADVVVATTQADFILALDGDDRLFGLEGNDFINGNQGDDIIHGNQGHDTLHGGQGNDVLRGGQGNDLLFGDLGDDTLYGDLGADTLTGGSGNNVFAIARRDDVPGFRSTGSANLPEADWIMDFKNNLDRIYLDGGLAFEDLHIFQGTGAYSSHTIIQDRITADYLAILNGIDFTTLDRNDFISLSPPSSSDPEIVFAPTPPAGISNPQPTPTPDPIVEPTPTPDPTPDPIVEPTPTPEPTPDPTPTPEPELTPGAVGFSAPVFTVREDGTAIAAVTVVRTGGSDGAISADVLLTDGTATAPADYINEPITITFGAGDTTPKTVPITIIDDTEVEPTETINLSLGNLSGGAVLETQNTAILEILDNDNPNNLELTQATYLGGAGNDEASAVRISPIDRAITIAGNLNGTAQLMRFSDRGDTLLSQTDLGGTVKDLDIDRDSGEIVTAGDFGIKLFDSTGTNLLWSQPGMVDRVAVANNGAIATLNIATDTVTLWSGTGTPLASTTLTGTDIRPSDIAINPLNNQVYVTGFNQVSTNLQTPFVRGFDTNLNLLWNTWDYSNTEVTSQNLGADTRGERLTIADDGTLYFLGKTDGGNNVFTRDGNTITTNLGTRLIQQDEYNNLSGAGSGSFTFLAKIDSNTGIIDRGQFIATRLSNGNANSFNPNSIAVDESGNVYIGGGGAASIQNRNLKTINGDPVGNYTLGEMAVLGVSADFTTRKFWTPLTESGDLNGSSGTVNSFAVAGDRAVIFGTVNNPGVATTSNAINPNPLGGSDAYLATWVV
>NC_019693.1|WP_015148528.1|2727741_2728137_-|hypothetical-protein
MSNSKWFKLLQSLGLEFWLPIPLLGVIFWGGSSWTADRVLSNNYSIDHPLQSNTHQSLELNLQVKVISIEAEIHLRENFTEVQVNTADSSLTELRFEFPVIEVTAVEQAIIEKLGLSREDVRKLVRYRIDY

Crispr_ID: NC_019693_23

• CRISPR_ID: NC_019693_23
• CRISPR_location: 2811556-2811629
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_23

Consensus_repeat	Method
TGCGCATGATCAACCCGCTAAGG	CRISPRCasFinder

spacers of NC_019693_23

>23.1|2811579|28|NC_019693|CRISPRCasFinder
TGAGGGAATTTTTTAAAATTCCAGGCGG

CRISPR arrays and Neighbor proteins around NC_019693_23

CRISPR arrays

The CRISPR arrays of NC_019693_23

>merge|NC_019693|23|2811556-2811629|CRISPRCasFinder
TGCGCATGATCAACCCGCTAAGGTGAGGGAATTTTTTAAAATTCCAGGCGGTGGGCATGATCAACCCGCTAAGG

>NC_019693|23|23|2811556-2811629|CRISPRCasFinder
TGCGCATGATCAACCCGCTAAGG	TGAGGGAATTTTTTAAAATTCCAGGCGG
TGGGCATGATCAACCCGCTAAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015148584.1|2800849_2801962_+|threonine-phosphate-decarboxylase	unknown	unknown	gnl|CDD|236009
NC_019693.1|WP_015148586.1|2803759_2805088_-|HlyC/CorC-family-transporter	unknown	unknown	gnl|CDD|224173
NC_019693.1|WP_015148581.1|2796689_2797538_+|type-4a-pilus-biogenesis-protein-PilO	unknown	unknown	gnl|CDD|371603
NC_019693.1|WP_015148596.1|2815397_2816228_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223999
NC_019693.1|WP_015148595.1|2814237_2814975_-|TIGR04255-family-protein	unknown	unknown	gnl|CDD|275082
NC_019693.1|WP_015148594.1|2813944_2814238_-|hypothetical-protein	unknown	unknown	gnl|CDD|237046
NC_019693.1|WP_044194976.1|2810515_2810695_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148585.1|2801980_2803408_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224169
NC_019693.1|WP_015148588.1|2809661_2810462_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148582.1|2797790_2800109_+|type-IV-pilus-secretin-family-protein	unknown	unknown	gnl|CDD|227133
NC_019693.1|WP_015148583.1|2800547_2800826_+|HU-family-DNA-binding-protein	unknown	unknown	gnl|CDD|259853
NC_019693.1|WP_015148592.1|2812827_2813157_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148591.1|2811972_2812773_+|PBS-lyase-HEAT-like-repeat-protein	unknown	unknown	unknown
NC_019693.1|WP_015148587.1|2805361_2808832_+|transcription-repair-coupling-factor	unknown	unknown	gnl|CDD|224118
NC_019693.1|WP_156824052.1|2819332_2821930_+|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|238923
NC_019693.1|WP_015148598.1|2817095_2817788_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148599.1|2818063_2818891_-|4-hydroxy-tetrahydrodipicolinate-reductase	unknown	unknown	gnl|CDD|234595
NC_019693.1|WP_015148580.1|2795886_2796693_+|pilus-assembly-protein-PilN	unknown	unknown	gnl|CDD|225707
NC_019693.1|WP_015148597.1|2816433_2817063_+|precorrin-8X-methylmutase	unknown	unknown	gnl|CDD|180325
NC_019693.1|WP_015148593.1|2813408_2813948_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015148584.1|2800849_2801962_+|threonine-phosphate-decarboxylase	gnl|CDD|236009	PRK07392, PRK07392, threonine-phosphate decarboxylase; Validated.	0
NC_019693.1|WP_015148586.1|2803759_2805088_-|HlyC/CorC-family-transporter	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	5.05211e-151
NC_019693.1|WP_015148581.1|2796689_2797538_+|type-4a-pilus-biogenesis-protein-PilO	gnl|CDD|371603	pfam11559, ADIP, Afadin- and alpha -actinin-Binding. This family is found in mammals where it is localized at cell-cell adherens junctions, and in Sch. pombe and other fungi where it anchors spindle-pole bodies to spindle microtubules. It is a coiled-coil structure, and in pombe, it is required for anchoring the minus end of spindle microtubules to the centrosome equivalent, the spindle-pole body. The name ADIP derives from the family being composed of Afadin- and alpha -Actinin-Binding Proteins localized at Cell-Cell Adherens Junctions.	0.00400661
NC_019693.1|WP_015148596.1|2815397_2816228_+|alpha/beta-hydrolase	gnl|CDD|223999	COG1073, COG1073, Hydrolases of the alpha/beta superfamily [General function prediction only].	4.61412e-21
NC_019693.1|WP_015148599.1|2818063_2818891_-|4-hydroxy-tetrahydrodipicolinate-reductase	gnl|CDD|234595	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional.	2.2338e-109
NC_019693.1|WP_015148594.1|2813944_2814238_-|hypothetical-protein	gnl|CDD|237046	PRK12297, obgE, GTPase CgtA; Reviewed.	0.00772994
NC_019693.1|WP_015148595.1|2814237_2814975_-|TIGR04255-family-protein	gnl|CDD|275082	TIGR04255, hypothetical_protein, TIGR04255 family protein. Members of this uncharacterized protein family are found broadly but sporadically among bacteria and archaea, including members of the genera Mycobacterium, Nostoc, Acinetobacter, Planctomyces, Geobacter, Streptomyces, Methanospirillum, etc. The function is unknown.	1.1512e-34
NC_019693.1|WP_156824052.1|2819332_2821930_+|EAL-domain-containing-protein	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	3.86396e-113
NC_019693.1|WP_015148582.1|2797790_2800109_+|type-IV-pilus-secretin-family-protein	gnl|CDD|227133	COG4796, HofQ, Type II secretory pathway, component HofQ [Intracellular trafficking and secretion].	1.88408e-42
NC_019693.1|WP_015148585.1|2801980_2803408_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224169	COG1249, Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion].	3.67545e-92
NC_019693.1|WP_015148583.1|2800547_2800826_+|HU-family-DNA-binding-protein	gnl|CDD|259853	cd13831, HU, histone-like DNA-binding protein HU. This subfamily includes HU and HU-like domains. HU is a conserved nucleoid-associated protein (NAP) which binds non-specifically to duplex DNA with a particular preference for targeting nicked and bent DNA. It is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. HU can induce DNA bends, condense DNA in a fiber and also interact with single stranded DNA. It contains two homologous subunits, alpha and beta, typically forming homodimers (alpha-alpha and beta-beta), except in E. coli and other enterobacteria, which form heterodimers (alpha-beta). In E. coli, HU binds uniformly to the chromosome, with a preference for damaged or distorted DNA structures and can introduce negative supercoils into closed circular DNA in the presence of topoisomerase I. Anabaena HU (AHU) shows preference for A/T-rich region in the center of its DNA binding site.	3.23605e-39
NC_019693.1|WP_015148597.1|2816433_2817063_+|precorrin-8X-methylmutase	gnl|CDD|180325	PRK05953, PRK05953, Precorrin-8X methylmutase.	6.57201e-142
NC_019693.1|WP_015148587.1|2805361_2808832_+|transcription-repair-coupling-factor	gnl|CDD|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0
NC_019693.1|WP_015148580.1|2795886_2796693_+|pilus-assembly-protein-PilN	gnl|CDD|225707	COG3166, PilN, Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion].	1.56651e-14

Protein sequences

>NC_019693.1|WP_044194976.1|2810515_2810695_-|hypothetical-protein
MAVILPLHPDTPGFPVSMSVMLETLETIEARSQLDILRDLLAIVPNFTRQDDGGFGVKG
>NC_019693.1|WP_015148588.1|2809661_2810462_+|hypothetical-protein
MTLETYSHPVNQLLTFGDCFKIKYDTNYLEKFGFTPEHIPELIRMAVDPELNWAESDTLEVWAPVHAWRSLGQLRAEEAIDPLIALFDEIEDIDWTSSEIPLVFKQIGPVAIPSLAAYLDKPEPDEYHIEIAGSSLTEIGTEYPEFRDECVKLLTEKLAKFQENSPALNGFLISDLIDLEAVESAQVMESAFAADCVDKLIVGDWDEVQFLLGLGPRKERKQIRISRTDKELIEWLKNGGQDQPSKGFSSSVQKTSQKKSKKKKRK
>NC_019693.1|WP_015148587.1|2805361_2808832_+|transcription-repair-coupling-factor
MACSSIIRTLGRSPLATELLTKLDRHHHIELNGISRFPKGLVVSAIAQKRDQSLLVVTATLEEAGRWAAQLEAMGWPTVHFYPTSEASPYELFDPEEETTWGQMQVLADLVRGENNLAIVTTEKALQPHLPPVNQFKPYCLTLTAKSEWNSKTLDEQLARMGYERVALVETEGEWSRRGDIVDIFPVSAELPVRLDWFGDELENIREFDPSTQRSLDKIPQLVLTPTSFSPLIQAHLPEAFRNADTAIPNDLELDESPDLRSLHRFLGVAFEQPASLLDYLSPDTIVAIDEPDRCSAHGDRWAEQVEEHFRTLPSKPLPLSRVHRNFSESLATAEPFDRISLSELVIPRKKDGPNISFDLDSRPVPVLPHQFAKLAELLREERDRRFNVFLISAQPSRSVSLLQEHDCPAQFIPNPRDYRAIEKLQVQHIPVALKYSGLAELEGFILSAFRIVIITDREFYGQHTLATPTYVRKRRRAASKQVDPNKLRQGDFVVHRHHGVGQFIKLEKLQNREYLVVKYSDGILRVPVDQLESLSRFRTTGGKRPELNKLTSKSWETTRNKVRKAVKKLAVDLLNLYAKRSDQQGFAYPPDMPWQQELEDSFSYQPTPDQLKATHDVKRDMESERPMDRLVCGDVGFGKTEVAIRAIFKAITAGKQVALLAPTTILTQQHYHTIKERFAPYPIQIGLLNRFRSPAERQDIQNRLATGELDLVVGTHSVLSKSIQFRDLGLLVVDEEQRFGVNQKEKIKALKTQVDVLTLTATPIPRTLYMSLSGVREMSLIATPPPSRRPIQTHLAPYDLETARSAIRQELDRGGQVFYVVPRVEGIEEVGAALQQMVPSARVAIAHGQMNPSELEAITIAFSSGEADILVCTTIIESGLDIPRVNTILIEDAHRFGLAQLYQLRGRVGRSGIQAHAWLFYPKSGRLTDEARKRLRAIKEFAQLGSGYQLAMRDMEIRGVGNLLGAEQSGQLDAIGFDLYMEMLEEAIREIRGQEIPTVEETQIDLTLTAFIPGDYIVDLDQKMSAYRSVALATSEKELAEIEADWRDRYGPIPKPVNQLMQVMKLKQIAKPLGFSRIKPEGTQNIVLETPMEEPAWNLLAQNLPANVQEKFVYRPGKVTVRGIGIMRAEYQLETLIDWLGRMQGALPEVAISQG
>NC_019693.1|WP_015148586.1|2803759_2805088_-|HlyC/CorC-family-transporter
MNSFTLEILIILLLILINGIFAMSEIALVSARKARLQQWANQGDRKARVALELANSPNRFLSTVQIGITLVGIFAGAFGGATIAENVVVLLDRLPVMVPYKGAIALLIVVVSITYLSLIFGELVPKRLALNNPERIATRIAIPMRLLAKLGAPVVHLLSASTDLVLRMLRTQPSNEPQVIEEEIKILLEQGTETGAFEQEEQAMVERVFRLDERRVSSLMTPRPDVIWLNLDDSVEENRHKIISSTHTRFPVCQNVLDNVLGVIQINDLLARSLLSQPIDLTAALRQPLFVPEHTKALKVLELFKQTGTHIALAVDEYGVIQGLVTLNDILEAIVGDMPSVNQPDDLQILQREDGSWLLDGMVSIEKFREVFNLKELPGEQQGNYHTLGGFVITHLGRIPIAADHFEWAGFRFEVMDMDGNRVDKILVMPVQGTLQNPLPIS
>NC_019693.1|WP_015148585.1|2801980_2803408_+|NAD(P)/FAD-dependent-oxidoreductase
MTLDYDLVVIGGTRPGIEAAIAAAKLQARVALVQPPQQAINAPPFSEGTGPIQTAELFDSPSILWGAPFPKDLPELARALEQSTQALASLGEERSPAVLASLGIDVIAEAGEFIPLPQLALDIKTRRLISRHYLLAPSFRSAIPDIPGLATTGYLTRETFHHFTEGTLPNSIAIIGSDPNGIELAQILVRLGIAVSLITSAPQILPKEDPEAAQLIQAQLEADGILVLTDTPVMAVESRQGEKIVQTENRAIACDEIFIACGFQSNIDGLNLDTVGVQFYRTPLGQRVQLNRKLQTTNPRIYGCGNLAGGYPLVNVARHEAQIAVKNALFFPRHRVKYWGIPWAFQTYPEIARVGLTEPQAKRRYDDVVVLMQYFKGIAGGRLQQETTGFCKVLVRKNGEILGAHILGPGASELIHSFALGMQNNLKVEAIATLPHIWPSLSEINQQTAQLWQEGRFTDNTFWQNLLDVWFNWRR
>NC_019693.1|WP_015148584.1|2800849_2801962_+|threonine-phosphate-decarboxylase
MNQPKHGGNLAWAATLAGCPPSSILDFSASISPLGPPPSVNAAIHSHLGELRNYPDPSYYSLRSQLGQADRLPPEWILPGNGAAELLTWAGWEFSTLPTTFLLTPAFGDYRRCLQTFGATVVDCPLLGDEEGGFLGVGEATAKAPSGLDCLIPKLQQQKAPGGLLLNNPHNPTGQLFSKTAIEPYLEQFALVVVDEAFMDFLLPGDQESLVSVIQDYPNLVILRSLTKFYSMPGLRLGYAIAHPDRLQRWQQWRDPWPVNILAAAAGEAVVQDTAFQEQTWTWLPPARSQLFDGLAGIPGLQPLPSAANFLLVRSHHSCSQLQRDLLTRHRILIRDCLSFPELGDAYFRVAVRLPDENQRLIAALTDILS
>NC_019693.1|WP_015148583.1|2800547_2800826_+|HU-family-DNA-binding-protein
MNKGELVDVVAEKANVTKKQADAVLTAALDAVIEAVSSGDKVTLVGFGSFEARERKAREGRNPKTGDKMEIPATKVPAFSAGKFFKEKVAPK
>NC_019693.1|WP_015148582.1|2797790_2800109_+|type-IV-pilus-secretin-family-protein
MKQPHALGCLFGASAIVVMASAPAMAVTQITGVNVNTSGGGVQVILDTQGGDRPQVFTVNRGTDVIADIINTQLNLPGGQSFRQNNPAPGIASIVVTPLDANSVRVIVSGSNSAPEVAINQADSAGINLGFNTGGVAASPNISPSTPPPPPGMTPPPGTTPGPEVLVPNPQITIEGGPAPIARPNQPSAPPFQPRAVAPPVGDIAVSNLPSATPEIDLGAGSTEIIPRLVLRDASVRDVLSLLARTAGLNLAYTPGVAPADGQAQQPGAEVADASPKISLDIENESVQDVFNYIIRLSALEANRVGDTIFVGTRLPDEARNVVVRTLRMNQVSSTDAAGFLTAQGAETQISRERLDIITIGEGAAARTIESRTPEILALRATQGDGPLLLSGLSVLTNERINGITLVGPPNKVEIATSFLSQLDLRRRQVAVNVKIVDVDLLATENFSTSFSFGINDSFFVNDGGAAVANFGGINPPTANTITGSEIVPPVLTNPLSGAGLQFDPNQTTQVPLTGPGAGALFLRPVPGISTNPRDVRVSDYTVFEVDPTTGVITPGTAEFSLPTLFQYPQKFLALLQAQVVSGNAKILTDPTMVVQEGETARLSLTQEIDQPGVFQQVNEDTGVVELFAQPGRIGDAGLTLNVSVSRIDDNGFVTMNIIPSVSAPTGRSTITGGTLLSTRTLQSGTIRIRDGQTLILSGIIQDIDRSFVSKIPILGDLPIIGSLFRSTQRENRRQEVIVLVTPQILDDSDNAGFGYGYAPGQEVQQMLNQNR
>NC_019693.1|WP_015148581.1|2796689_2797538_+|type-4a-pilus-biogenesis-protein-PilO
MTVSEQFMAMEAARAEEAPPPGSYKIGSFVLTPQIQGILIAVLGLGLAGFAAFKMLLPAMEEQTNLKTQIAAKEAEIANQQSKIRQMDEARANLATTQQQKENVLALFAQGATLETLLLDINQIVRQSGGNLESFKPLESNPNDWIFTEAPAQAGGAAASPPADPAAAPPPTTPSLTLSQAVEGKTMELEMAGNYQQTLDTLRRLERLQQMVVFGEFTSTLGEGTQRIFVDPDGKITEQAPANLDTVFNLIAVMPLPPEQLKNLAAPPPPPAAAEGEQPPAQ
>NC_019693.1|WP_015148580.1|2795886_2796693_+|pilus-assembly-protein-PilN
MYSLEINFLNDRADYKPPAPRPSTSQTSRQQTTMLIGGLAAGVSAIAVVMGGWFVVNNQNTELQGQLATLESQSGSLGAQVQEVEAINAEIQQLNTQITFFANIFNTSVKPMSALLQELRDRLPPGVQVANLNHQIEQAPPEEIQASSPWTKVKQTIEIQGYAKTFDDVNDFVLTLKRSPFFNDSQTQLIDATLVDNPVQVECDPSFQGQQVTCPPTDFQLPQVVEYNINATVSNVLASEVLADLQRTRAEGLTTRINLLEQQGVIQR
>NC_019693.1|WP_015148591.1|2811972_2812773_+|PBS-lyase-HEAT-like-repeat-protein
MTLETYSHPVNQLLSFGDCFKIKNDTNYLEKFGFTPEHIPELIRMTVDPELNWAESDTLEVWAPVHAWRSLGQLRAEEAIDPLISILDEIEDIDWTSREMPSVFGKIGPAAIPSLAAYLDNPAPDIYHLSIPASCLQKIGTEHPDSRDECVKILTEKLAKFQENDPTFNGFLLLDLVKLKAVESVPVIQSAFAADCIDESIMGDWDEVQFRLGLGPRKNPENIRKAKVHEAMMELLKNQGEAQPSKGFSSSIKKTPKKGQKKKKGK
>NC_019693.1|WP_015148592.1|2812827_2813157_-|hypothetical-protein
MKVTIKDIDILQTLHPSQVADYLRDRGWQQQQSIPQKAIIWRKEINPGNAVAVILPLHPDTPGFPVSMSVMLETLETIEGRSQLNILKDLLAIFPNFTRQDDGGFGVKG
>NC_019693.1|WP_015148593.1|2813408_2813948_-|hypothetical-protein
MRTEHFWEQVNESRLRQGDYLPNCLVPLPIFDPTTFSEGSDLQSVDVEIREYDLIVLTQSCDLENKKVRFVALSPIYSLEEFEEINPKFAKKGQWENVRRGRVEGLYLLASPTEPDNNRKSLVVDFGEIHSLPYDYIEKYAINLGPRWRLNSPFLEHFSQAFARFFMRVGLPSAIEPFK
>NC_019693.1|WP_015148594.1|2813944_2814238_-|hypothetical-protein
MATICALPPKTTKPSPIPLVRESFDMPDFQSAEKQKLAELTEAIWQKLIAIEQLQEALEDDSEVTYRSVPPKRTFTVRMLCQFKGRGQPRKYPIDDE
>NC_019693.1|WP_015148595.1|2814237_2814975_-|TIGR04255-family-protein
MQKTRHYSRSPITQAVIDLQIELSNDVTVEHLSDLHLQVQADYPQCQNLLVFQGQIMGVTKVEETASQSLMGYGFFSRDRKQIVQARRDGFSFTRLAPYERWENFRDEAQRLWRIYRSLTTPNRLTRLSLRYINRLDLPLPFEDFKEYLRTVPEVSFDLPQALSGYFLQLQIPYPELTGILVLNQAIIPPPKAEVVSVLVDIDLVREEDIPNDEIQLWELIEQYHAQSIQIFESCITDRSRELMI
>NC_019693.1|WP_015148596.1|2815397_2816228_+|alpha/beta-hydrolase
MNPKLKHLLIGEFSLKRLVKSLLFVYISIGIYGYFFSERMIFIPQPASYSQLPGMRMLTSANEKQIAAVYLANPQADYTILYSHGNAEDLGDVLPVLTQFQNIGFAVLSFDYQGYGISEGNPTERTAVQDMEAAYFYLTETLKIPPERIIVYGRSVGGGPALELAARYPVGGLVVESSFTSIFRTVTRIPIYPVDKFNNIRNIERVNCPVLVIHGTEDEVIPFWHGEALFAAAAEPKQALWVEGAGHNDLIWVAGDRHSAALLGFVGLLEGNEPAE
>NC_019693.1|WP_015148597.1|2816433_2817063_+|precorrin-8X-methylmutase
MEWHGSDAQSLAIIDREIGDHIFSPAEYEIVRRVIYATADFEYKSLIRFSEQALQAGAAALAARSTIVVDVPMVQVGISPHIQNTFANPVYCSMDALTRPQKEKTRAAWGIETLAKRYPEGIFILGEAQTSLTTLVELIEAEEIRPALVIGTPAGFVGVDAAKARLNDSMIQNIRVDGRKGSAVVAVAILNGLVDLAWQAYGQEGRGMI
>NC_019693.1|WP_015148598.1|2817095_2817788_-|hypothetical-protein
MLIPLTRETFDDLIPGIATGAQYAYYGGKIDKILKRVLISVAGIGLLTLTANALPDNWRPFLLIIGIIFGLYWLWGPIASASRENYQCRRYKYSGFWRGEVWDVFVTEEVVGTKETVSPRGELVILENRERRLNLEVGDETGFSTRVLVPLRKEHKAIAPGDMAEMVVMSNRPDLGRIAKVSDIYLPRIDFWISDYPYLRRDLFVEISQQMEDLNAPRPRRRKARREEFR
>NC_019693.1|WP_015148599.1|2818063_2818891_-|4-hydroxy-tetrahydrodipicolinate-reductase
MANQLPIPVVVNGAGGKMGREVVQAVAEAPDMILVGAVDRNPEYLGQDIGEVIGCGPLEIPVLNDLEGTLGMALQEKQSAVMVDFTHPNSVYENTRAAIAYGIRPVIGTTGMSPEQIQDLAAFAEKSSMGCAIIPNFSIGMVLLQQAAIAASQHFDHVEIIELHHNQKADAPSGTAIQTAQMLAEMGKTFNPPQVKETEKIAGARGSEAGEGIRIHSIRLPGLIAHQEVIFGAAGQVYTLRHDTSDRACYMPGVLLSIRKILQLKTLVYGLEKLL
>NC_019693.1|WP_156824052.1|2819332_2821930_+|EAL-domain-containing-protein
MAIAIIIAIGVVLTIRETGGFQPIELVTYDWMMRNRWYNPGLDDRLLLVKITETDIQTQQKWPLSDRVVAQVLEEIAKFEPAVIGLDLYRDVPQSPGHHDLQLQLQSLDSVIGITKLSDAQEPGVPPPPHLPSEAVGFNDIVNDPDGIARRNLLFAQDQEGNTFYSFALRVALKYLSDRDIAIDNSPTHPQGIVLGKALITPLESHSGGYQTIDAEGYQILLNYRSPGSISQEVTLNQILNREVDPSWVKDKIVLIGTTASSEKDLFFTPYGIQTETETFKMPGVRVHAQMVSQLLSSALDGKPIFWFLPNWMEILWIVSCGVIGGLVPWQIQHPLKLGLRVILGVGGIITIGFGLFHGGGWIPMAAPTVAFMIALSGVVASKLLYTAFHDDLTGLPNRAAFMNELDRAYRRSQPKTLPFFLTLGKLPQTLPEKKPAVVSLDSKLPPVPRLLAVLFLDLDRFKIINDGLGHDMGDLLLMAIAERIRTLMRQPQPNGIEAVTIARVGGDEFAILLDNLYRSEDAINMGEFLYRQIARPFTLKGQDIYTTTSIGLALGRADDSRNLLRDAHTAMYRAKALTKARPQVFESAMQNNAVARFQLETDLRRAINAGATPVNGKIESEFLVYYQPLIDLKSGKIIGFEALVRWQHPERGLVFPGEFIPVAEETGSIVPLGELVLVIACWQICKWQEEFPQSPPLMVSVNLSGKQFAQPNLIEVVQRILDQTNLDPACLKLEITESVVMDEVEVAIEMLSQMKALNLKLGIDDFGTGYSSLSYLHRFPTDTLKVDRSFVMRMVEGDQNSAIVKTIIALAHNLKMDVIAEGVETAEQLAQLRSLGCECGQGYFFAKPLPAEQIEALLKSDPTW

Crispr_ID: NC_019693_24

• CRISPR_ID: NC_019693_24
• CRISPR_location: 2918809-2918920
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_24

Consensus_repeat	Method
AGGGAAGGGGGTTGGGGGGTTAGGTCTCTTCACCCCCAACCCA	CRISPRCasFinder

spacers of NC_019693_24

>24.1|2918852|26|NC_019693|CRISPRCasFinder
ATCTTTCCGGCCCCCCCTTCCCTCTG

CRISPR arrays and Neighbor proteins around NC_019693_24

CRISPR arrays

The CRISPR arrays of NC_019693_24

>merge|NC_019693|24|2918809-2918920|CRISPRCasFinder
AGGGAAGGGGGTTGGGGGGTTAGGTCTCTTCACCCCCAACCCAATCTTTCCGGCCCCCCCTTCCCTCTGAGGGAAGGGGGTTGGGGGGTTAGGTCTCTTCCCCCCAACCCAG

>NC_019693|24|24|2918809-2918920|CRISPRCasFinder
AGGGAAGGGGGTTGGGGGGTTAGGTCTCTTCACCCCCAACCCA	ATCTTTCCGGCCCCCCCTTCCCTCTG
AGGGAAGGGGGTTGGGGGGTTAGGTCTCTTCCCCCCAACCCAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015148650.1|2935137_2935497_-|response-regulator	unknown	unknown	gnl|CDD|381164
NC_019693.1|WP_015148642.1|2922870_2926641_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|223910
NC_019693.1|WP_015148640.1|2915539_2918377_-|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl|CDD|223716
NC_019693.1|WP_015148639.1|2914805_2915300_-|chemotaxis-protein-CheW	unknown	unknown	gnl|CDD|366716
NC_019693.1|WP_015148644.1|2927311_2928763_-|IS66-family-transposase	unknown	unknown	gnl|CDD|376980
NC_019693.1|WP_015148632.1|2901107_2902586_+|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl|CDD|214599
NC_019693.1|WP_015148647.1|2932516_2932687_+|DUF4177-domain-containing-protein	unknown	unknown	gnl|CDD|379366
NC_019693.1|WP_015148649.1|2934000_2934744_+|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	unknown
NC_019693.1|WP_015148636.1|2907967_2908363_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350220
NC_019693.1|WP_015148645.1|2929662_2931039_-|ATP-binding-protein	unknown	unknown	gnl|CDD|379062
NC_019693.1|WP_044196973.1|2926688_2927180_-|purine-binding-chemotaxis-protein-CheW	unknown	unknown	gnl|CDD|223905
NC_019693.1|WP_015148646.1|2931925_2932180_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148633.1|2903398_2905987_+|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl|CDD|223716
NC_019693.1|WP_044196965.1|2908463_2913752_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NC_019693.1|WP_015148634.1|2906070_2907273_+|chemotaxis-specific-protein-glutamate-methyltransferase-CheB	unknown	unknown	gnl|CDD|234828
NC_019693.1|WP_015148631.1|2898842_2900168_+|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl|CDD|214599
NC_019693.1|WP_083896765.1|2914197_2914785_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_019693.1|WP_015148648.1|2932683_2933343_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148635.1|2907733_2907967_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148641.1|2918969_2922653_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|223910

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015148650.1|2935137_2935497_-|response-regulator	gnl|CDD|381164	cd19937, REC_OmpR_BsPhoP-like, phosphoacceptor receiver (REC) domain of BsPhoP-like OmpR family response regulators. Bacillus subtilis PhoP (BsPhoP) is part of the PhoPR two-component system that participates in a signal transduction network that controls adaptation of the bacteria to phosphate deficiency by regulating (activating or repressing) genes of the Pho regulon upon phosphorylation by PhoR. When activated, PhoPR directs expression of phosphate scavenging enzymes, lowers synthesis of the phosphate-rich wall teichoic acid (WTA) and initiates synthesis of teichuronic acid, a non-phosphate containing replacement anionic polymer. Members of this subfamily belong to the OmpR family of DNA-binding response regulators, which are characterized by a REC domain and a winged helix-turn-helix (wHTH) DNA-binding output effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.68439e-36
NC_019693.1|WP_015148642.1|2922870_2926641_-|PAS-domain-S-box-protein	gnl|CDD|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.06052e-68
NC_019693.1|WP_015148640.1|2915539_2918377_-|hybrid-sensor-histidine-kinase/response-regulator	gnl|CDD|223716	COG0643, CheA, Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms].	2.88015e-166
NC_019693.1|WP_015148639.1|2914805_2915300_-|chemotaxis-protein-CheW	gnl|CDD|366716	pfam01584, CheW, CheW-like domain. CheW proteins are part of the chemotaxis signaling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and other related proteins that are involved in chemotaxis. The CheW-like regulatory domain in CheA binds to CheW, suggesting that these domains can interact with each other.	3.5039e-10
NC_019693.1|WP_015148644.1|2927311_2928763_-|IS66-family-transposase	gnl|CDD|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	1.72151e-39
NC_019693.1|WP_015148632.1|2901107_2902586_+|methyl-accepting-chemotaxis-protein	gnl|CDD|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	3.89795e-35
NC_019693.1|WP_015148636.1|2907967_2908363_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350220	cd09872, PIN_Sll0205-like, VapC-like PIN domain of Sll0205 protein and homologs. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of the Synechocystis sp. (strain PCC 6803) Sll0205 protein and other uncharacterized homologs are included in this subfamily. They are similar to the PIN domains of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.19778e-34
NC_019693.1|WP_015148645.1|2929662_2931039_-|ATP-binding-protein	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	6.09581e-05
NC_019693.1|WP_044196973.1|2926688_2927180_-|purine-binding-chemotaxis-protein-CheW	gnl|CDD|223905	COG0835, CheW, Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms].	9.77879e-27
NC_019693.1|WP_015148633.1|2903398_2905987_+|hybrid-sensor-histidine-kinase/response-regulator	gnl|CDD|223716	COG0643, CheA, Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms].	6.22821e-155
NC_019693.1|WP_044196965.1|2908463_2913752_-|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	0
NC_019693.1|WP_015148634.1|2906070_2907273_+|chemotaxis-specific-protein-glutamate-methyltransferase-CheB	gnl|CDD|234828	PRK00742, PRK00742, chemotaxis-specific protein-glutamate methyltransferase CheB.	2.47476e-119
NC_019693.1|WP_015148631.1|2898842_2900168_+|methyl-accepting-chemotaxis-protein	gnl|CDD|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	9.97472e-37
NC_019693.1|WP_083896765.1|2914197_2914785_+|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	1.49098e-11
NC_019693.1|WP_015148647.1|2932516_2932687_+|DUF4177-domain-containing-protein	gnl|CDD|379366	pfam13783, DUF4177, Domain of unknown function (DUF4177).	0.00105039
NC_019693.1|WP_015148641.1|2918969_2922653_-|PAS-domain-S-box-protein	gnl|CDD|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.72601e-68

Protein sequences

>NC_019693.1|WP_015148640.1|2915539_2918377_-|hybrid-sensor-histidine-kinase/response-regulator
MDFNDIQELLGAFIAETDEFLQSLETQLLAMEQIETAEARKSTIKEMFRAAHSIKGSALMFGFQSLSTAAHRIEDCFAILRDRQEDTPLSSHSITQLLQGVDLLKKLTAQSTALVREKQAEDPKDFQGDLEAIARIKQELEAECGGLKQPAEWMQKHPANTQVIQTIFQQDLPPIFNRLETELSQIQAETVEDSYRVFNEIYYQLSGLSGMLEVPELGEIAECLRAAVDTPNLSVEDLKILGWAIAQNLETLREQVLQELPIVLQPMDIPDSTPDVVISPVPSPPPLLPSDSPPSATPPEPSLLPTPTPGESGVKPTIRVELDRLTELVDLVGELVINRTHLEVQETQLRAEVKRLRRHIRDLNQFGVQLREEYDRLAGEKSHRGRNTAHPLGFDALEMDHYTEFHDTARETIETTQAIAHSSAKIDEVALNLDRSTDRLRRICDRLRSQVMQLRVVSFSRAVDHLPRAIRDMSRTYNKDVNLLLIGRDTKIDESLLHALRDPLVHLVRNAFDHGIESPEDRKAAGKPPNGQIEIEARHQGGQTIITISDDGQGIDPETIRDRLVELNLVSEEQALELSLNELYDFLFWSGFSTQREVNDLSGRGVGLDIVRSNLRQVRGTVKVDSRLGRGTSFIIKLPLMLSISDALLVRIEHQTLALPLDAVEEILHVNASEIQMAMYQPMLRWRDEYIRLVPLNDLLHYQESSHDLPSPIPVGEDYMPVLVLSSSEGILAIVVDRLVGQQELVVKPLPQPLSKPTGILGCTILGDGEVVSILDVDDLIGQLHPHIQKAVVIQNETQGRNHPLPPGTRTPVPLLPPLPSQPQILVIDDSYTIRQMLSLTLTRSRYRVAQAKDGQDALEQLHHGLKCALIIADIEMPRMDGFEFLAEVKENPQFSHIPVAMLTSRSGAKHRQRAMDLGAVQYFTKPYNERQLLEAIAQLIGATL
>NC_019693.1|WP_015148639.1|2914805_2915300_-|chemotaxis-protein-CheW
MFSPSKYSRRFHNKKAAIQRTPTRKLVLFEVAGETYAIAIERVQRVLTEFTTQGTLEGGRSLVKIDADLITLLDLSKLFVIPKDYQEERSYLIVCTLTNGDRIGIPLQNLPAILDIPEDKFAEIPTSYRQGREGKNAAPAAVEKIITTDAGTVAFYLNLDKLLD
>NC_019693.1|WP_083896765.1|2914197_2914785_+|Uma2-family-endonuclease
MVHEVSMGDRQLTSYTLPSPDLAPENGLSYPFTVDQTPGSEQSSTQERVTQTLSQLLIQHLRGTSAIVSLHPRPVYLEAASAYCYPDLMVTHDPRDLDCCQGLDGVVQYPCLIIDVISHPFSGSEKPGQFEQYRQIETLEEYVWLDPTQPKLNCWRQIEPGVWEAYLYESGDDVYLDSLSFLIEIEAIYDGMLTP
>NC_019693.1|WP_044196965.1|2908463_2913752_-|AAA-family-ATPase
MAILDYQIGELLHESSNSRIYRALGLSDNQPVILKLLNQAYPSPEKIAQFQREYETTRSLNFPGIINAYRLERSDRQWVMVIEDFGGVSLKTIIQNQPLTLSQFLPIAINIAEILDLVHQQQIIHKDINPSNLVLNPNTQELKLIDFGISTQLSRENPTFRNPNLLEGTLLYIAPEQTGRMNRSVDYRSDFYSLGVTFYELLTGRVPFPSDDPLALVYSHLAQQPIPPHQLNTEIPEAISRIILKLMSKNAEDRYQSAYGLKRDLEECLRQWQNTEQIQPFPLATQDSSDRFQLPQKLYGRQQEIAELLSGFERVCSGGQTELMLVAGYSGIGKSALVQEVYKPITRQRGYFISGKFDQLQRDIPYASLVQAFRSLILQLLTESATQIATWREKLLTALGPNAQIIIDVIPELKAIIGEQPPIPELPGMEAENRFKLVFQNFIQVFTQAEHPLVVFLDDLQWSDNASLKLLALLMTTPASQYLYLIGAYRDNEVSSVHPLMLTLEELQKNQATVNQIFLTPLSLSDVTQLVADTLNTTEEIARPLAELVEVKTKGNPFFVNQFLSSLYKNKVLNFESDRRCWQWDIHQIAAQNITDNVVDLMVEQVKKLPETTQTCLKLAACIGYRFDLETLALVSQKSRSETAAALWEAISETLILPLGDDYKLMEVDIPEIAQGVTVEYKFAHDRIQQAAYSLIPETDKQAVHLQIGQLFLENTPSENREQNIFDIVHQLNLGREAIREVSLQQELVSLNEIAGKKAKASAAFKSALRYFQTAIELLSQNSWEEQYDLTLALYLEAIEAALFSGSYALMEEFSEVILQQAITVLDTVKVYELKIQGYVSQNELGEAKKSGLEILERLGMPLPEQPTPSDIGQAMTETRAIWAGKRISDLIDMPPMLDPYKLAASRVFVSLATPAAVGFPEIYPLVLLRMAGLFLQYGNTSQAPGGYGAYAILLCGVENDLESGYEFGLLSLNLQERLNVKEIETKTLHIFNTFIRHWKEPVRNSIKNFLQAYQSGLETGDILYGGWALWMYCVHSYWAGEELLQVNAAISTYSDEIIKLKQAIALRWMESFRESVFNLLTSTEEPWTLNSDTFDESSQLLSYQQAGDRIALCLSYLNKIMLCYLFERFPEAAENVALGEEYVGMAIAMHTVPLFNFYDSLTHLALYPDASEPEQQRILEKVTANQEKMQLWAQHAPMNYLHKYYLVEAERARVLCNPSDARDYYDRAIALAKENEYLNEEALAYELAARFYIGRNIPHLARFYLVEAHYAYQRWGATAKVKHLETRYPQLLELRTSTSSKLSTTTTSGSSSGETLDIATVLKASQAISSEIQLNKLLAQLLTLAIENAGAQKGVLILSDNNQLKIEAAKLPDREVQILESLPLETGNFVPPAIINYVARTQENVILANATQEGIFTSEPYILQQQTQSLLCAAIVNQGKLIGILYLENNLATGAFTQERIELLQVISAQAAISLENAQLYRTLEDKVIERTAQLAEANEEISALNELLKSDNLRMSAELDVTRQLQQKMLPNPEELQAIPGLEIAGFMEPADEIGGDYYDVLNHEGHIKIGIGDVTGHGLEAGMVMVMVQTAVRTLLVNNETDYVKFLNTINRMIHDNVKRMRTDKNLTLALLDYADGVLRITGQHEEVLVVRGTGEIERLDTVDLGFPVGLELDIADFITQAEVELNPGDGVVLYTDGIPEAENMAKEFYGMDRLCEVVSQYWQESAEAIRQLVIQDVREFIGEQKVFDDITLVVMKQR
>NC_019693.1|WP_015148636.1|2907967_2908363_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MLLLDAHIWIRWQNPQPSSIVLSKPLIDRIETADSVAISAISCWELGQLVKRQRVQISLPLDEWVQAALEDIQVLPIDQAIALKASQLPEHHRDPADRIIIATALIYDAALISLDAIFPTYTELQGRLISG
>NC_019693.1|WP_015148635.1|2907733_2907967_+|hypothetical-protein
MEPLRIITKAMNGQLVIDLPPSLMSDRTYEVIILPVISGESVATPRRRHPSEKLAGTVYLLDDLTAPATPESDWDLS
>NC_019693.1|WP_015148634.1|2906070_2907273_+|chemotaxis-specific-protein-glutamate-methyltransferase-CheB
MNKKPIRVLLVEDSPVALMIFKRLLGSTPEIEIVGTAKTGIEGLELIPQVHPQVICTDLNMPKMDGLEFTKEVMAKFPCPILVVSSSVQAEDTLTVFNLLKAGAVDVFPKPRQGVMGNFDAIRHELISKIKVLAGVTVFTLHRRGAANRETQRVSPRVVPPKNTGKILIPEQKRVDPVVQTVKIPASYSPAPPVPAALSPNLPTGAGSFQGVKIVAIGASTGGPQALHTILCQLPPKFPVPVICVQHISEGFLKGLVDWLGSECQLPVKIAPAGERPEPGIIYFPPEQKHLEFDSQGRFLYSSMGPVSGHRPSVTVTFNAVAKFYRRAALGILLTGMGRDGADGMLELFKQGGITIAQNESSCVVFGMPREAIALSAAQYILPISEIAPLLLKRLMSDRH
>NC_019693.1|WP_015148633.1|2903398_2905987_+|hybrid-sensor-histidine-kinase/response-regulator
MIDDEELRVTFKVASEEHLQKLNDGLLHLEEQPEDLGKLEELLREAHSLKGDAGMLGVKDIATLAHQWEHLLGTVKRKETTLTPELCDRLYHGLDAIAKLVQESVTGEAAGVNTFYVLAYLMGAASDINESETKSEPQPPQEAQKSPAREKLPPEQRNSSQETLDPIESVTETQGRETVEETEEQSDLDLEEPPEEAAREMLEVIPPVEVAVSVPVKVSATVNGHNLSQKHPIPEISKPFTPAPPPPGGDRGRESGPSKPPVLPPLAVTPPQASSHYRIDTIRVETRNLDSLMTQTGELTVSKIRIAHRLSEVEEIVTLWEEWSRDSFVNRFALEEVIRGNRNGSLDRLESFHHRTEDRLERLGQIVNRLRNSVYEDNARLDTIADELEEGIRTLRLLPLSTIFTLFPRMVRDLAKQEGKQVELLIEGGETRADKRILEEMKDPLMHIIRNAIDHGIETPGDRQQTGKPPKATIVLKGYQTANNIIIEIRDDGRGLDLEKIKQTALKRGICREEELAAMTPHQIHSLIFTPGFSTRTFVTEVSGRGVGLDVVRTNVERLKGSIHIDSTPGVGTTLRLSLGTTLATAHVLLVEVEGIAYALPVEFVQLARLVPESDIFALEGRETMILDGQPVSVVKLADLLELPPRGILNSSKSMNTSSLPCIILQVGEERLGLLVDALVDEQDVVLKPQSKLLKRVRNVAGATILGTGEVCMVLNPHDLLKSVRKPGKSIAPSKPQPESDRKLLVLLVEDSIATRTQEKRILENAGYEVVTAVDGLDGYNKLRTRDFDAVISDVQMPNLDGLGLVSKIRQHKEYSELPIILVTSLASDDDKRRGAEAGANSYIPKSSFNQEVLLETLKRLI
>NC_019693.1|WP_015148632.1|2901107_2902586_+|methyl-accepting-chemotaxis-protein
MLDSLKLRGRILACIIIPLLVSSVLATLIVSNVRKVDKLDQQIGFSSEVIDYLAEATLHAIRMERSTRGYLVNAKDRHRQGFETGSESYSRLIKSLEPKIAQLEDPIQRQRFEEYTQLGNQLRQINLQTLQLAQTGQMEEAVALFSTDQSSNITREIESIYNAFVQQERETLALRKVRAKEALDLSLAIAGWGTAMIGLVTIAIGAKLVSSIRDRIERAIHEVATSSTEFAATFSHQETSTNAQATSVNQTTASMEELNASSRATAEQAESAAANAILVLNLVDSSNHHELPVHPSYRLGSNPSGIPSRNRQMGHQNTSLKETVNQIAKRIEQLTQQLSQIDEIASNVSNIANQTNMLALNASVEAVRAGEAGKGFGVVATEIRKLADHSGRCADRINSLVKEIQSATSLTVQVTAEGTKTVEVVVEAIDEIVNNTQQISLTAQQQAIAIQQVFEAMNALNRIASETVNSISQAKLGTDKLNQAALDLKEMV
>NC_019693.1|WP_015148631.1|2898842_2900168_+|methyl-accepting-chemotaxis-protein
MLFNLKLKARILLGYSIPLIFSITSAGLVFVSSQQVQEEVKILETGAAIVRESDRLALRLMSIQRSARGYMINQRDFIPEAIEADITSLKNALTFLQANVEDAGQKARLERMLDLSQRTIDYNNNLINLVQQNRIPEAVQAYSTPEREQLNRELEALLVEFNQWEDDLQKEKSDRTDEVLGLLITLVLLSTGIMAIVAWGLGWAIASRITDTLGETTNTIASSSTEIAAMTEQQERVANQQASAVHETCSTMEQLGLSSQESSERAEATTVQVEQIANQILHLSEQVNQIDKIAGLVSDIANQTNMLALNAAVEAVRAGEQGKGFGVVASEIRKLADRSKQSAEKISELVNDIERATNSAVMITKDGTRSVESVVSAVNHIAVNAQQISLSAKQQALAIQQTLDAMNSLTQNAQETASGIAQTKISIQQLNQVALKLQREI
>NC_019693.1|WP_015148641.1|2918969_2922653_-|PAS-domain-S-box-protein
MFEPSSPLLTANFIPHGHCYLWNPVLVWLHAGSDLAIALAYFSIVAMLIYFVSRRPDLPFSRIFLLFAAFIITCGFTHVLEVWTLWHPDYWVSGSIKALTAGISLLTALEMVPTLPAALALPSAKAELEVANQALQGEIKERQQAEAALKRLASIIENTPDFVGICDSQGKGIYLNPASRKMTGISEDQPASDFTAFDFVQEGPDRQGLEQAIATTISQGVWTGETLIKRRNGDLFPSSQVLIAHKEQNGELDCISTVIRDISDRKQQEKALAESEERFRQLVENAADAFFLTTLEGKILGVNQRACESLGYSQNQLLALNLEAIEPRFRSEERTLAVAQLHPSEALTLESLHRRADGSTFPVEIRLGKFSRQGETLLLALVRDISDRKAIEKALEAERQRLTTLFDGIPAFLYLVDRSNTVQLANRQFVEFLGEPGSAATLLNPGGKLHSEIRTQVFETQKPQQWEWQDPNTGRTYQIYDYPCTDGEGKRLVLEMGIDISDRKQAEKALQTSEARFRSLIEATSQIIWNTAADGEFVTEQPAWSSFTGQTFDQLKGRGWLNAVHPEERQQMAQAWDHAVQNRVLYEVEHRLRRHDGEYRYMSVRAVPILNTADGSIREWLGVYTDISDRKLAQVTCDQFFTISLDLLSIFGFDSTFQRVNPAWTTILGYSEQELMGQSFMDFVHPDDIEATIAETQKLTTGRETLYFENRYRCKDGSYKWLAWSANPSTEQQLLYAVAHDITPLKQTEEQFRLLAAEQAQLLQELKTRQNALDEAAIVSETDSDDMITFVNDQFCEISGYSRAELIGKNHRMINSGYHPKSLFEEMWKTISNGRVWKGELRNQCKNGQYYWVDTTISPIFDAQGKVVKYIGIRFDITDRKQVAEELEKFAQDRKAEADELTQQVLKLLMEIKGAAKGDLTVRAEVNNNVLGALADSFNFLVSSLKKVVTGIQELATEVRSATRESIANTQDLTERAEEQAQQVEFSLRQIERMANSIQDICTVAQKAENVAHQAAETAEVGGQSVDRAVEGINELRQTISQTGKMIKRLGESSQQIGKIVTSISQIAAQTNLLALNATIEAARAGEQGLGFAVVAEEIRKLADRSGSATEEISEIVEQIRSEIGRVTEAMEAGTQEVVAGTKLAAEAKHHLVAIIEVSRQMNALVQNITRAATNQTENASEIATVMQKVSSISTTTAEKSVQVRQSLDGLAIAVNQLQESVSNFRS
>NC_019693.1|WP_015148642.1|2922870_2926641_-|PAS-domain-S-box-protein
MLINGIGFQLYFAIGSAPDWVGIQNWAEWAIALSYLGMTVILLQITVSRLHCRFLWIVSAFLAVATGSRFFHLFSTPILPVSTAWQTLSYGLEGVSAIAVMIALFTYRQGIRETLGSGIFSRGSFLQMALDGLPWAVSWQDSQGVYLGGNQRFAEQVGVTSPAQVIGKTNAGLCWGGKRLENWAKINPEDSQTLLVQVPNSYPGDGSESLWKIHQCPVKTSQEKPVGIASTYEKFPGYAEAIASNFTEFLNQIEEGFLIQKRDGTILDANEKASQLYGMERTQLRGKNFFNQLSSFGQSQVDFEAAVSKGGSLRWKALKPKAGSFLDVEISGKPLTLVDNREVMGVSVRDVSSCLKLETELRQREEEFKLFLEHLPAAVAMLDRQMCYVMVSQRWVKDYKLDHREDFQSVKNIIGRSHYELFPELPDPVKDKLQRVLEGESFSCDAEGYTRVDGSMDWVKWEMYPWRDRTGEIGGIMLLTEVITDRIQTEQERMRLFNLVESSLNEIYIFDVETLRFEYVNKGACLNLGYSPEEILKKTAMDINPAVGRLEDVKTALTPLLEGREQRIRFEGMHRRADGSIYPIEIYLQLAQQTHKPSCVAIVLDITERKQAERALQESEQQFRLMADTVPATIWIADADKQVTYFNKRWVEFTGRSLEQDLGHGWVQILHPDDRERAVHTYQTAFDKRQPFQLELRFKRWDGEYCWSWMSGLPRFDSEGNFFGYIGSGLDITERKQAEEARRESEEGFRSLVESVKDYAIIRLDVAGRVASWNMGAQRIKGYRAPEILGQPFQQFYTLEDRTSGKPEAELKAAQSEGRFEDEGYRVKKDGSKFWANVIITALRDAKGELQGFSKITRDVTEQRRNQEALEQLAADLENRVDQRTQELQEINEKLQQEVGDRIGAEAEKTQLIADLEIMSAQRQAEMDSLTEQVVKMLGQIKGAAKGDLTVRAAVTNDILGALADSFNFLISSLRKVVTGVQKLATEANTATGESISNTQELAHQAQEQAEKIDETIQKIQKIVNSIEEVFTLSQQAENVAQQAAEKAQVGGDSVDRAVAAINELRQTLSQTGKTIERLGESSGQIGKIVTSISQIAAQTNLLALNATIEAARAGEQGLGFAVVAEEIRKLADRSGLATEEISEIVEQIRSEIGRAIVAMEAGTQEVAIGTKLAAEAKTHLIEIIQVSGEMNALVEHISLAATKQTNSATEIVSMIRAVSAISGNTAEKSVQVQNSLDGLAISVESLQQSVAHFRS
>NC_019693.1|WP_044196973.1|2926688_2927180_-|purine-binding-chemotaxis-protein-CheW
MSELPGSPNSGNLKQFLLFGQRESLFAVDLLAVREVLFLGQQPIAPVPNTRHFVLGLTNLRGEILAVADFGRFLRTEAVDSHSVHSRILILEAPDPRDGTLVMMRMGLAVSRVQGVISVHLDRMVSSMDVGEELAPFLRGLYDWTGRLVMILDVEAIAQSEGW
>NC_019693.1|WP_015148644.1|2927311_2928763_-|IS66-family-transposase
MDESITIGGIKIPRADWERTPESVKNVVRNIEQRIAAIEERLGLNASNSSIPPSKQPPIAKEKKQEKRPRRKRGGQKGHKGFTRHLYEPSECSEIIDHQPETCKHCQAPLTGEDAQPYRHQIVDIPPVAPVVTEHRLHALSCQCCGQTTRAELPNDINPSGYGERLQSLVALLSGAYRLSHNQVQTLMRDLWQVHLSTGTVNRIRQRVSQKLSQVVDEARAYIMKSGTAYVDETSWSQNNGDGNNPENASAWLWTAVSNNVAVYQVTLNRARSSAEALLGKNYTGLVVSDRYSVYNGWTVEQRQVCWAHLKRDFKRMAERSGVSKDIGEALLKQTKRLFHWWHRVRDGTLSTELFQAAMARLRQSVHHLLSEAASLCHSSREQTPLAKTARTCEQILKLEPALWTFVEVNAVEPTNNTAERAFPRAVIWRDLSYGSWSRSGSEFVERLLTVVTSLRFQERPVLEFLMQVLHSESVSLLPLPPE
>NC_019693.1|WP_015148645.1|2929662_2931039_-|ATP-binding-protein
MEIQDALHWTDNLIFDQTGKHLASLHRAILLGAWEGKGYQDIAQEYHCSGDHVKKSASELWKLLSELLGEDVKKKNVRSLIENGIFYSFNTKILNVGNSHNVYNTLYKFSKNPKTRSPNGTPDADSAPRHDLSQAPEYHRLYNRTDELATLKHWILTENSRIVTLTGLSGIGKTALARQLVEHIKDKFDRILWRSHRKLPNLNILQSHIIEFLAPSPPSKNPSIIQYLHSRNSLLDHLRNHRCLIILDDFQAVFNPGELVGNYRAEYQNYGQLLYEIGRFSHQSCLVLLSWEQPLEIAALELENPYCKTLPVLGLGQDATKILRKRKLKDERKWSDLIQLYGGNPLWLNIMASTILELFNGSVQQFLSYPSLFLGDLEPLLKKHYERLCESEKVLLEWLANEDKTVTLSQKPQDLLSDEAFLKGIQSLNRRNLLETSSGFTLQPVIKQYIQNLVQSGH
>NC_019693.1|WP_015148646.1|2931925_2932180_+|hypothetical-protein
MRTYSASGDRIVVGYITGKQGQYEVFHRSPHSHDLYFRNSATNRSTGFRVKSNGNYIGPDGAAYYNNASVIAAIQNCYNLGKYK
>NC_019693.1|WP_015148647.1|2932516_2932687_+|DUF4177-domain-containing-protein
MRYEYNAKVVDLEKVNLECNSMGQQGWELVTALPYSRENCCKQSIPTVVLIFKKSA
>NC_019693.1|WP_015148648.1|2932683_2933343_+|hypothetical-protein
MSCFHDQRDRINYGHLENPEFGKFINNLGKIPLLAHHPACNYYHNHIIWIGNLPLCLGCLMMSSGIITGFLLLPHLGVLKTLPFFVLLFIGVLLYVPAVIQIWVQKKSYKIMARFCLGVSVVFLGYAGLWLTPNSMTGWILKVGFITVFYGVWHLTLRVRSQYSKSPCTSCPEGRFPLCSYTTHRIPKLAKKYFSESDGTNPEADEFVTALQSIYSDSQ
>NC_019693.1|WP_015148649.1|2934000_2934744_+|PEP-CTERM-sorting-domain-containing-protein
MLKTKLLSGIITVTVATISSIGFAAEAIALTLYLTPGETSTIRWSYRPNFFPNWEHEDTLIQWNLLDLYQGVLQFAPDSLIEESSDGTQYAITNDAISNRGLRENAQINYRPLSAQNILGGETTAGFANWSNEEQIRIYTGVQTWDIDRLFEQVKFINETYYGNYSITSIEDMHHMYLGSVTTRVFVGGVSSSYMADLQLDLSNYNPPPADERQSVPEPGSAIALLTLAIAGLSSVKKKSQSVESNP
>NC_019693.1|WP_015148650.1|2935137_2935497_-|response-regulator
MSKILVVDDVPSELEMIGRILKKAGMEVVVATNGEEAIARIQETAPDLVILDVVMPRMNGFEVIRELRGDRKTSKLPVVFCSQKNTEIDKTWGMDLGADAYITKPVDPQQLVHIVERLL

Crispr_ID: NC_019693_25

• CRISPR_ID: NC_019693_25
• CRISPR_location: 2929311-2929398
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_25

Consensus_repeat	Method
GATTTGGGGTCATCAAATTTACC	CRISPRCasFinder

spacers of NC_019693_25

>25.1|2929334|42|NC_019693|CRISPRCasFinder
TCTTGGACAGGCGATCACTCTCGCGCCCCTACAAGAAATAAG

CRISPR arrays and Neighbor proteins around NC_019693_25

CRISPR arrays

The CRISPR arrays of NC_019693_25

>merge|NC_019693|25|2929311-2929398|CRISPRCasFinder
GATTTGGGGTCATCAAATTTACCTCTTGGACAGGCGATCACTCTCGCGCCCCTACAAGAAATAAGGATTTGGGGTCATTAAATTTACC

>NC_019693|25|25|2929311-2929398|CRISPRCasFinder
GATTTGGGGTCATCAAATTTACC	TCTTGGACAGGCGATCACTCTCGCGCCCCTACAAGAAATAAG
GATTTGGGGTCATTAAATTTACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015148650.1|2935137_2935497_-|response-regulator	unknown	unknown	gnl|CDD|381164
NC_019693.1|WP_015148642.1|2922870_2926641_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|223910
NC_019693.1|WP_015148651.1|2936257_2937631_+|phosphomethylpyrimidine-synthase	unknown	unknown	gnl|CDD|237359
NC_019693.1|WP_015148640.1|2915539_2918377_-|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl|CDD|223716
NC_019693.1|WP_015148639.1|2914805_2915300_-|chemotaxis-protein-CheW	unknown	unknown	gnl|CDD|366716
NC_019693.1|WP_015148644.1|2927311_2928763_-|IS66-family-transposase	unknown	unknown	gnl|CDD|376980
NC_019693.1|WP_015148652.1|2937701_2938355_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148646.1|2931925_2932180_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148653.1|2938364_2939837_-|N-6-DNA-methylase	unknown	unknown	gnl|CDD|380294
NC_019693.1|WP_015148649.1|2934000_2934744_+|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	unknown
NC_019693.1|WP_015148636.1|2907967_2908363_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350220
NC_019693.1|WP_015148645.1|2929662_2931039_-|ATP-binding-protein	unknown	unknown	gnl|CDD|379062
NC_019693.1|WP_044196973.1|2926688_2927180_-|purine-binding-chemotaxis-protein-CheW	unknown	unknown	gnl|CDD|223905
NC_019693.1|WP_015148647.1|2932516_2932687_+|DUF4177-domain-containing-protein	unknown	unknown	gnl|CDD|379366
NC_019693.1|WP_044196965.1|2908463_2913752_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NC_019693.1|WP_015148654.1|2939909_2941301_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|177909
NC_019693.1|WP_083896765.1|2914197_2914785_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_019693.1|WP_015148648.1|2932683_2933343_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148635.1|2907733_2907967_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148641.1|2918969_2922653_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|223910

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015148650.1|2935137_2935497_-|response-regulator	gnl|CDD|381164	cd19937, REC_OmpR_BsPhoP-like, phosphoacceptor receiver (REC) domain of BsPhoP-like OmpR family response regulators. Bacillus subtilis PhoP (BsPhoP) is part of the PhoPR two-component system that participates in a signal transduction network that controls adaptation of the bacteria to phosphate deficiency by regulating (activating or repressing) genes of the Pho regulon upon phosphorylation by PhoR. When activated, PhoPR directs expression of phosphate scavenging enzymes, lowers synthesis of the phosphate-rich wall teichoic acid (WTA) and initiates synthesis of teichuronic acid, a non-phosphate containing replacement anionic polymer. Members of this subfamily belong to the OmpR family of DNA-binding response regulators, which are characterized by a REC domain and a winged helix-turn-helix (wHTH) DNA-binding output effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.68439e-36
NC_019693.1|WP_015148642.1|2922870_2926641_-|PAS-domain-S-box-protein	gnl|CDD|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.06052e-68
NC_019693.1|WP_015148640.1|2915539_2918377_-|hybrid-sensor-histidine-kinase/response-regulator	gnl|CDD|223716	COG0643, CheA, Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms].	2.88015e-166
NC_019693.1|WP_015148639.1|2914805_2915300_-|chemotaxis-protein-CheW	gnl|CDD|366716	pfam01584, CheW, CheW-like domain. CheW proteins are part of the chemotaxis signaling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and other related proteins that are involved in chemotaxis. The CheW-like regulatory domain in CheA binds to CheW, suggesting that these domains can interact with each other.	3.5039e-10
NC_019693.1|WP_015148644.1|2927311_2928763_-|IS66-family-transposase	gnl|CDD|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	1.72151e-39
NC_019693.1|WP_015148653.1|2938364_2939837_-|N-6-DNA-methylase	gnl|CDD|380294	NF033452, BREX_1_MTaseX, BREX-1 system adenine-specific DNA-methyltransferase PglX. This protein, PglX, is a site-specific DNA methyltransferase associated BREX (bacteriophage exclusion) type 1 systems. The phage resistance appears not to be through restriction-modification, as phage DNA appears not to get degraded, but it does manage to inhibit phage replication.	1.68642e-20
NC_019693.1|WP_015148636.1|2907967_2908363_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350220	cd09872, PIN_Sll0205-like, VapC-like PIN domain of Sll0205 protein and homologs. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of the Synechocystis sp. (strain PCC 6803) Sll0205 protein and other uncharacterized homologs are included in this subfamily. They are similar to the PIN domains of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.19778e-34
NC_019693.1|WP_015148645.1|2929662_2931039_-|ATP-binding-protein	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	6.09581e-05
NC_019693.1|WP_044196973.1|2926688_2927180_-|purine-binding-chemotaxis-protein-CheW	gnl|CDD|223905	COG0835, CheW, Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms].	9.77879e-27
NC_019693.1|WP_015148651.1|2936257_2937631_+|phosphomethylpyrimidine-synthase	gnl|CDD|237359	PRK13352, PRK13352, phosphomethylpyrimidine synthase ThiC.	0
NC_019693.1|WP_044196965.1|2908463_2913752_-|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	0
NC_019693.1|WP_015148654.1|2939909_2941301_+|FAD-dependent-oxidoreductase	gnl|CDD|177909	PLN02268, PLN02268, probable polyamine oxidase.	1.89166e-112
NC_019693.1|WP_083896765.1|2914197_2914785_+|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	1.49098e-11
NC_019693.1|WP_015148647.1|2932516_2932687_+|DUF4177-domain-containing-protein	gnl|CDD|379366	pfam13783, DUF4177, Domain of unknown function (DUF4177).	0.00105039
NC_019693.1|WP_015148641.1|2918969_2922653_-|PAS-domain-S-box-protein	gnl|CDD|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.72601e-68

Protein sequences

>NC_019693.1|WP_015148644.1|2927311_2928763_-|IS66-family-transposase
MDESITIGGIKIPRADWERTPESVKNVVRNIEQRIAAIEERLGLNASNSSIPPSKQPPIAKEKKQEKRPRRKRGGQKGHKGFTRHLYEPSECSEIIDHQPETCKHCQAPLTGEDAQPYRHQIVDIPPVAPVVTEHRLHALSCQCCGQTTRAELPNDINPSGYGERLQSLVALLSGAYRLSHNQVQTLMRDLWQVHLSTGTVNRIRQRVSQKLSQVVDEARAYIMKSGTAYVDETSWSQNNGDGNNPENASAWLWTAVSNNVAVYQVTLNRARSSAEALLGKNYTGLVVSDRYSVYNGWTVEQRQVCWAHLKRDFKRMAERSGVSKDIGEALLKQTKRLFHWWHRVRDGTLSTELFQAAMARLRQSVHHLLSEAASLCHSSREQTPLAKTARTCEQILKLEPALWTFVEVNAVEPTNNTAERAFPRAVIWRDLSYGSWSRSGSEFVERLLTVVTSLRFQERPVLEFLMQVLHSESVSLLPLPPE
>NC_019693.1|WP_044196973.1|2926688_2927180_-|purine-binding-chemotaxis-protein-CheW
MSELPGSPNSGNLKQFLLFGQRESLFAVDLLAVREVLFLGQQPIAPVPNTRHFVLGLTNLRGEILAVADFGRFLRTEAVDSHSVHSRILILEAPDPRDGTLVMMRMGLAVSRVQGVISVHLDRMVSSMDVGEELAPFLRGLYDWTGRLVMILDVEAIAQSEGW
>NC_019693.1|WP_015148642.1|2922870_2926641_-|PAS-domain-S-box-protein
MLINGIGFQLYFAIGSAPDWVGIQNWAEWAIALSYLGMTVILLQITVSRLHCRFLWIVSAFLAVATGSRFFHLFSTPILPVSTAWQTLSYGLEGVSAIAVMIALFTYRQGIRETLGSGIFSRGSFLQMALDGLPWAVSWQDSQGVYLGGNQRFAEQVGVTSPAQVIGKTNAGLCWGGKRLENWAKINPEDSQTLLVQVPNSYPGDGSESLWKIHQCPVKTSQEKPVGIASTYEKFPGYAEAIASNFTEFLNQIEEGFLIQKRDGTILDANEKASQLYGMERTQLRGKNFFNQLSSFGQSQVDFEAAVSKGGSLRWKALKPKAGSFLDVEISGKPLTLVDNREVMGVSVRDVSSCLKLETELRQREEEFKLFLEHLPAAVAMLDRQMCYVMVSQRWVKDYKLDHREDFQSVKNIIGRSHYELFPELPDPVKDKLQRVLEGESFSCDAEGYTRVDGSMDWVKWEMYPWRDRTGEIGGIMLLTEVITDRIQTEQERMRLFNLVESSLNEIYIFDVETLRFEYVNKGACLNLGYSPEEILKKTAMDINPAVGRLEDVKTALTPLLEGREQRIRFEGMHRRADGSIYPIEIYLQLAQQTHKPSCVAIVLDITERKQAERALQESEQQFRLMADTVPATIWIADADKQVTYFNKRWVEFTGRSLEQDLGHGWVQILHPDDRERAVHTYQTAFDKRQPFQLELRFKRWDGEYCWSWMSGLPRFDSEGNFFGYIGSGLDITERKQAEEARRESEEGFRSLVESVKDYAIIRLDVAGRVASWNMGAQRIKGYRAPEILGQPFQQFYTLEDRTSGKPEAELKAAQSEGRFEDEGYRVKKDGSKFWANVIITALRDAKGELQGFSKITRDVTEQRRNQEALEQLAADLENRVDQRTQELQEINEKLQQEVGDRIGAEAEKTQLIADLEIMSAQRQAEMDSLTEQVVKMLGQIKGAAKGDLTVRAAVTNDILGALADSFNFLISSLRKVVTGVQKLATEANTATGESISNTQELAHQAQEQAEKIDETIQKIQKIVNSIEEVFTLSQQAENVAQQAAEKAQVGGDSVDRAVAAINELRQTLSQTGKTIERLGESSGQIGKIVTSISQIAAQTNLLALNATIEAARAGEQGLGFAVVAEEIRKLADRSGLATEEISEIVEQIRSEIGRAIVAMEAGTQEVAIGTKLAAEAKTHLIEIIQVSGEMNALVEHISLAATKQTNSATEIVSMIRAVSAISGNTAEKSVQVQNSLDGLAISVESLQQSVAHFRS
>NC_019693.1|WP_015148641.1|2918969_2922653_-|PAS-domain-S-box-protein
MFEPSSPLLTANFIPHGHCYLWNPVLVWLHAGSDLAIALAYFSIVAMLIYFVSRRPDLPFSRIFLLFAAFIITCGFTHVLEVWTLWHPDYWVSGSIKALTAGISLLTALEMVPTLPAALALPSAKAELEVANQALQGEIKERQQAEAALKRLASIIENTPDFVGICDSQGKGIYLNPASRKMTGISEDQPASDFTAFDFVQEGPDRQGLEQAIATTISQGVWTGETLIKRRNGDLFPSSQVLIAHKEQNGELDCISTVIRDISDRKQQEKALAESEERFRQLVENAADAFFLTTLEGKILGVNQRACESLGYSQNQLLALNLEAIEPRFRSEERTLAVAQLHPSEALTLESLHRRADGSTFPVEIRLGKFSRQGETLLLALVRDISDRKAIEKALEAERQRLTTLFDGIPAFLYLVDRSNTVQLANRQFVEFLGEPGSAATLLNPGGKLHSEIRTQVFETQKPQQWEWQDPNTGRTYQIYDYPCTDGEGKRLVLEMGIDISDRKQAEKALQTSEARFRSLIEATSQIIWNTAADGEFVTEQPAWSSFTGQTFDQLKGRGWLNAVHPEERQQMAQAWDHAVQNRVLYEVEHRLRRHDGEYRYMSVRAVPILNTADGSIREWLGVYTDISDRKLAQVTCDQFFTISLDLLSIFGFDSTFQRVNPAWTTILGYSEQELMGQSFMDFVHPDDIEATIAETQKLTTGRETLYFENRYRCKDGSYKWLAWSANPSTEQQLLYAVAHDITPLKQTEEQFRLLAAEQAQLLQELKTRQNALDEAAIVSETDSDDMITFVNDQFCEISGYSRAELIGKNHRMINSGYHPKSLFEEMWKTISNGRVWKGELRNQCKNGQYYWVDTTISPIFDAQGKVVKYIGIRFDITDRKQVAEELEKFAQDRKAEADELTQQVLKLLMEIKGAAKGDLTVRAEVNNNVLGALADSFNFLVSSLKKVVTGIQELATEVRSATRESIANTQDLTERAEEQAQQVEFSLRQIERMANSIQDICTVAQKAENVAHQAAETAEVGGQSVDRAVEGINELRQTISQTGKMIKRLGESSQQIGKIVTSISQIAAQTNLLALNATIEAARAGEQGLGFAVVAEEIRKLADRSGSATEEISEIVEQIRSEIGRVTEAMEAGTQEVVAGTKLAAEAKHHLVAIIEVSRQMNALVQNITRAATNQTENASEIATVMQKVSSISTTTAEKSVQVRQSLDGLAIAVNQLQESVSNFRS
>NC_019693.1|WP_015148640.1|2915539_2918377_-|hybrid-sensor-histidine-kinase/response-regulator
MDFNDIQELLGAFIAETDEFLQSLETQLLAMEQIETAEARKSTIKEMFRAAHSIKGSALMFGFQSLSTAAHRIEDCFAILRDRQEDTPLSSHSITQLLQGVDLLKKLTAQSTALVREKQAEDPKDFQGDLEAIARIKQELEAECGGLKQPAEWMQKHPANTQVIQTIFQQDLPPIFNRLETELSQIQAETVEDSYRVFNEIYYQLSGLSGMLEVPELGEIAECLRAAVDTPNLSVEDLKILGWAIAQNLETLREQVLQELPIVLQPMDIPDSTPDVVISPVPSPPPLLPSDSPPSATPPEPSLLPTPTPGESGVKPTIRVELDRLTELVDLVGELVINRTHLEVQETQLRAEVKRLRRHIRDLNQFGVQLREEYDRLAGEKSHRGRNTAHPLGFDALEMDHYTEFHDTARETIETTQAIAHSSAKIDEVALNLDRSTDRLRRICDRLRSQVMQLRVVSFSRAVDHLPRAIRDMSRTYNKDVNLLLIGRDTKIDESLLHALRDPLVHLVRNAFDHGIESPEDRKAAGKPPNGQIEIEARHQGGQTIITISDDGQGIDPETIRDRLVELNLVSEEQALELSLNELYDFLFWSGFSTQREVNDLSGRGVGLDIVRSNLRQVRGTVKVDSRLGRGTSFIIKLPLMLSISDALLVRIEHQTLALPLDAVEEILHVNASEIQMAMYQPMLRWRDEYIRLVPLNDLLHYQESSHDLPSPIPVGEDYMPVLVLSSSEGILAIVVDRLVGQQELVVKPLPQPLSKPTGILGCTILGDGEVVSILDVDDLIGQLHPHIQKAVVIQNETQGRNHPLPPGTRTPVPLLPPLPSQPQILVIDDSYTIRQMLSLTLTRSRYRVAQAKDGQDALEQLHHGLKCALIIADIEMPRMDGFEFLAEVKENPQFSHIPVAMLTSRSGAKHRQRAMDLGAVQYFTKPYNERQLLEAIAQLIGATL
>NC_019693.1|WP_015148639.1|2914805_2915300_-|chemotaxis-protein-CheW
MFSPSKYSRRFHNKKAAIQRTPTRKLVLFEVAGETYAIAIERVQRVLTEFTTQGTLEGGRSLVKIDADLITLLDLSKLFVIPKDYQEERSYLIVCTLTNGDRIGIPLQNLPAILDIPEDKFAEIPTSYRQGREGKNAAPAAVEKIITTDAGTVAFYLNLDKLLD
>NC_019693.1|WP_083896765.1|2914197_2914785_+|Uma2-family-endonuclease
MVHEVSMGDRQLTSYTLPSPDLAPENGLSYPFTVDQTPGSEQSSTQERVTQTLSQLLIQHLRGTSAIVSLHPRPVYLEAASAYCYPDLMVTHDPRDLDCCQGLDGVVQYPCLIIDVISHPFSGSEKPGQFEQYRQIETLEEYVWLDPTQPKLNCWRQIEPGVWEAYLYESGDDVYLDSLSFLIEIEAIYDGMLTP
>NC_019693.1|WP_044196965.1|2908463_2913752_-|AAA-family-ATPase
MAILDYQIGELLHESSNSRIYRALGLSDNQPVILKLLNQAYPSPEKIAQFQREYETTRSLNFPGIINAYRLERSDRQWVMVIEDFGGVSLKTIIQNQPLTLSQFLPIAINIAEILDLVHQQQIIHKDINPSNLVLNPNTQELKLIDFGISTQLSRENPTFRNPNLLEGTLLYIAPEQTGRMNRSVDYRSDFYSLGVTFYELLTGRVPFPSDDPLALVYSHLAQQPIPPHQLNTEIPEAISRIILKLMSKNAEDRYQSAYGLKRDLEECLRQWQNTEQIQPFPLATQDSSDRFQLPQKLYGRQQEIAELLSGFERVCSGGQTELMLVAGYSGIGKSALVQEVYKPITRQRGYFISGKFDQLQRDIPYASLVQAFRSLILQLLTESATQIATWREKLLTALGPNAQIIIDVIPELKAIIGEQPPIPELPGMEAENRFKLVFQNFIQVFTQAEHPLVVFLDDLQWSDNASLKLLALLMTTPASQYLYLIGAYRDNEVSSVHPLMLTLEELQKNQATVNQIFLTPLSLSDVTQLVADTLNTTEEIARPLAELVEVKTKGNPFFVNQFLSSLYKNKVLNFESDRRCWQWDIHQIAAQNITDNVVDLMVEQVKKLPETTQTCLKLAACIGYRFDLETLALVSQKSRSETAAALWEAISETLILPLGDDYKLMEVDIPEIAQGVTVEYKFAHDRIQQAAYSLIPETDKQAVHLQIGQLFLENTPSENREQNIFDIVHQLNLGREAIREVSLQQELVSLNEIAGKKAKASAAFKSALRYFQTAIELLSQNSWEEQYDLTLALYLEAIEAALFSGSYALMEEFSEVILQQAITVLDTVKVYELKIQGYVSQNELGEAKKSGLEILERLGMPLPEQPTPSDIGQAMTETRAIWAGKRISDLIDMPPMLDPYKLAASRVFVSLATPAAVGFPEIYPLVLLRMAGLFLQYGNTSQAPGGYGAYAILLCGVENDLESGYEFGLLSLNLQERLNVKEIETKTLHIFNTFIRHWKEPVRNSIKNFLQAYQSGLETGDILYGGWALWMYCVHSYWAGEELLQVNAAISTYSDEIIKLKQAIALRWMESFRESVFNLLTSTEEPWTLNSDTFDESSQLLSYQQAGDRIALCLSYLNKIMLCYLFERFPEAAENVALGEEYVGMAIAMHTVPLFNFYDSLTHLALYPDASEPEQQRILEKVTANQEKMQLWAQHAPMNYLHKYYLVEAERARVLCNPSDARDYYDRAIALAKENEYLNEEALAYELAARFYIGRNIPHLARFYLVEAHYAYQRWGATAKVKHLETRYPQLLELRTSTSSKLSTTTTSGSSSGETLDIATVLKASQAISSEIQLNKLLAQLLTLAIENAGAQKGVLILSDNNQLKIEAAKLPDREVQILESLPLETGNFVPPAIINYVARTQENVILANATQEGIFTSEPYILQQQTQSLLCAAIVNQGKLIGILYLENNLATGAFTQERIELLQVISAQAAISLENAQLYRTLEDKVIERTAQLAEANEEISALNELLKSDNLRMSAELDVTRQLQQKMLPNPEELQAIPGLEIAGFMEPADEIGGDYYDVLNHEGHIKIGIGDVTGHGLEAGMVMVMVQTAVRTLLVNNETDYVKFLNTINRMIHDNVKRMRTDKNLTLALLDYADGVLRITGQHEEVLVVRGTGEIERLDTVDLGFPVGLELDIADFITQAEVELNPGDGVVLYTDGIPEAENMAKEFYGMDRLCEVVSQYWQESAEAIRQLVIQDVREFIGEQKVFDDITLVVMKQR
>NC_019693.1|WP_015148636.1|2907967_2908363_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MLLLDAHIWIRWQNPQPSSIVLSKPLIDRIETADSVAISAISCWELGQLVKRQRVQISLPLDEWVQAALEDIQVLPIDQAIALKASQLPEHHRDPADRIIIATALIYDAALISLDAIFPTYTELQGRLISG
>NC_019693.1|WP_015148635.1|2907733_2907967_+|hypothetical-protein
MEPLRIITKAMNGQLVIDLPPSLMSDRTYEVIILPVISGESVATPRRRHPSEKLAGTVYLLDDLTAPATPESDWDLS
>NC_019693.1|WP_015148645.1|2929662_2931039_-|ATP-binding-protein
MEIQDALHWTDNLIFDQTGKHLASLHRAILLGAWEGKGYQDIAQEYHCSGDHVKKSASELWKLLSELLGEDVKKKNVRSLIENGIFYSFNTKILNVGNSHNVYNTLYKFSKNPKTRSPNGTPDADSAPRHDLSQAPEYHRLYNRTDELATLKHWILTENSRIVTLTGLSGIGKTALARQLVEHIKDKFDRILWRSHRKLPNLNILQSHIIEFLAPSPPSKNPSIIQYLHSRNSLLDHLRNHRCLIILDDFQAVFNPGELVGNYRAEYQNYGQLLYEIGRFSHQSCLVLLSWEQPLEIAALELENPYCKTLPVLGLGQDATKILRKRKLKDERKWSDLIQLYGGNPLWLNIMASTILELFNGSVQQFLSYPSLFLGDLEPLLKKHYERLCESEKVLLEWLANEDKTVTLSQKPQDLLSDEAFLKGIQSLNRRNLLETSSGFTLQPVIKQYIQNLVQSGH
>NC_019693.1|WP_015148646.1|2931925_2932180_+|hypothetical-protein
MRTYSASGDRIVVGYITGKQGQYEVFHRSPHSHDLYFRNSATNRSTGFRVKSNGNYIGPDGAAYYNNASVIAAIQNCYNLGKYK
>NC_019693.1|WP_015148647.1|2932516_2932687_+|DUF4177-domain-containing-protein
MRYEYNAKVVDLEKVNLECNSMGQQGWELVTALPYSRENCCKQSIPTVVLIFKKSA
>NC_019693.1|WP_015148648.1|2932683_2933343_+|hypothetical-protein
MSCFHDQRDRINYGHLENPEFGKFINNLGKIPLLAHHPACNYYHNHIIWIGNLPLCLGCLMMSSGIITGFLLLPHLGVLKTLPFFVLLFIGVLLYVPAVIQIWVQKKSYKIMARFCLGVSVVFLGYAGLWLTPNSMTGWILKVGFITVFYGVWHLTLRVRSQYSKSPCTSCPEGRFPLCSYTTHRIPKLAKKYFSESDGTNPEADEFVTALQSIYSDSQ
>NC_019693.1|WP_015148649.1|2934000_2934744_+|PEP-CTERM-sorting-domain-containing-protein
MLKTKLLSGIITVTVATISSIGFAAEAIALTLYLTPGETSTIRWSYRPNFFPNWEHEDTLIQWNLLDLYQGVLQFAPDSLIEESSDGTQYAITNDAISNRGLRENAQINYRPLSAQNILGGETTAGFANWSNEEQIRIYTGVQTWDIDRLFEQVKFINETYYGNYSITSIEDMHHMYLGSVTTRVFVGGVSSSYMADLQLDLSNYNPPPADERQSVPEPGSAIALLTLAIAGLSSVKKKSQSVESNP
>NC_019693.1|WP_015148650.1|2935137_2935497_-|response-regulator
MSKILVVDDVPSELEMIGRILKKAGMEVVVATNGEEAIARIQETAPDLVILDVVMPRMNGFEVIRELRGDRKTSKLPVVFCSQKNTEIDKTWGMDLGADAYITKPVDPQQLVHIVERLL
>NC_019693.1|WP_015148651.1|2936257_2937631_+|phosphomethylpyrimidine-synthase
MRKEWVAKRQGQSNVTQMNYARQGIITEEMDYVAKRENLPVELIRDEVARGRMIIPANINHLNLEPMCIGIASKCKVNANIGASPNSSDINEELDKLNLSVKYGADTVMDLSTGGGNLDEIRTAIINTSPVPIGTVPIYQALESVHGNMESLTPNDFLHIIEKHAQQGVDYMTIHAGILIEHLPLVKNRITGIVSRGGGILARWMLHHHKQNPLYTHFDDIIEIFKKYDVSFSLGDSLRPGCQHDASDEAQLAELKTLGQLTRRAWEHNVQVMVEGPGHVPMDQIEFNVKKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADIARHRIGARDRDDELSHARYNFDWNRQFELSLDPERAKEYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDADALTELEKFLAKEPVTQG
>NC_019693.1|WP_015148652.1|2937701_2938355_+|hypothetical-protein
MIDELQNVERIRAGLETALNELIQDIATLQIFPPDRFPLGWRKAAKGRTVWRLLEEMITQNLEVKHQDIGIQSFSPATSEVGVYDFIFSLDGQERVFVNIKSAIKGERLSKDDISKARKLEEFFSADATRILLIATFEIEFLANMTLQINKCTVLPVMWIPDIYVNPSNNANLQSSRYKSIQTATRRTGLEFLELLRGEIQKADEKGAAKRRKQADR
>NC_019693.1|WP_015148653.1|2938364_2939837_-|N-6-DNA-methylase
MGRHLKKIETKAGIDRRETGYYSTPDFVAEFIAKALIELNLQGRTALDPCVGRGEMVIPLLNQGISVDGMDILPFDLPESIHFTQTDFLQFYQQKKLLSILNTPIDLDYDFYLANPPYNCHEVAYIRDNKNRLSRLFVDIGVHNMYALFIAALIDCAKPGALIGLITLDSFLTAKAHQNLRHKILQNCAVHYLLLCSNDLFLDQGADVRTCIMILQKGTDYQGVVKVGNRPLSQRDFQRILIQKQWMELPLEKITLAGEADHSEFIIDIPDEVRNLFESPRLGNRFPCVTGISTGSDRTYLSKHPRPGFTIPFYKNPGSCRFFTKPNAYLIDDFLSIAETIPNFTIRNKSLLYQPGITCSSMGVTFSACYLPAHSTYGVNANIITSDSDTWWLLAYLNSHLVTFIVRSLLNRSNMITSGYVARIPIPKLSPIALHQMSAIAREAHQKQVSPKAAIHYVEQINQIIWKELDFTADTIAIIQNFCKNLIRAT
>NC_019693.1|WP_015148654.1|2939909_2941301_+|FAD-dependent-oxidoreductase
MSPIPPVKWLFNRRRFVQLSLFASTLGLSLACSDNQAQSSPQKVLVIGAGIAGLAAARELQGQGFQVTVLEGRDRIGGRIHTSRTLGFPVDLGASWIHGITDNPIATLAKEWQIPILPTDFNNIILYNSQGNPISDRDFAVSYALYEQIRDRAASIAENSEQDLSIAAALQQVLAAQTLTPQQAQLIEWGLNSEFVTEFGADLESLSSWYADDDLEFDGGDYLFPQGYDQIITGLANNLEIQLQQKVTEILYSGSGVSVTTERETFTADAAIVTLPLGVLKSESIKFSPELPDNKQAAINRLSMGVLNKVVLKFPEQFWPQDYQVLGYLHENGPDFSEFLNWEFYSQEPALIALMGGSFAREIEQLSEEEIRSRVLRVLRRSYGDRIPEPESIIVTRWSQDPFAFGSYSHIAVGGDSGDRDLLAEPIGDRLFFAGEATSRDYPSTVHGAYLSGIREAKRLINR

Crispr_ID: NC_019693_26

• CRISPR_ID: NC_019693_26
• CRISPR_location: 2972124-2972215
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_26

Consensus_repeat	Method
ACCTCCGGTCCCCTCCCCTTGCCAAGG	CRISPRCasFinder

spacers of NC_019693_26

>26.1|2972151|38|NC_019693|CRISPRCasFinder
GGAGGGTTAGGGTGGGGTTCTTCTTGGGCGATCGCCAG

CRISPR arrays and Neighbor proteins around NC_019693_26

CRISPR arrays

The CRISPR arrays of NC_019693_26

>merge|NC_019693|26|2972124-2972215|CRISPRCasFinder
ACCTCCGGTCCCCTCCCCTTGCCAAGGGGAGGGTTAGGGTGGGGTTCTTCTTGGGCGATCGCCAGACCTCCGGTCCCCTCCCCTTGCCAAGG

>NC_019693|26|26|2972124-2972215|CRISPRCasFinder
ACCTCCGGTCCCCTCCCCTTGCCAAGG	GGAGGGTTAGGGTGGGGTTCTTCTTGGGCGATCGCCAG
ACCTCCGGTCCCCTCCCCTTGCCAAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015148679.1|2970479_2971922_-|DUF1565-domain-containing-protein	unknown	unknown	gnl|CDD|284923
NC_019693.1|WP_015148675.1|2964115_2965267_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|223736
NC_019693.1|WP_015148685.1|2977662_2979366_-|MCE-family-protein	unknown	unknown	gnl|CDD|178642
NC_019693.1|WP_015148673.1|2961634_2961871_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148681.1|2973075_2974506_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl|CDD|129571
NC_019693.1|WP_044196996.1|2975698_2976748_+|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase	unknown	unknown	gnl|CDD|234858
NC_019693.1|WP_015148684.1|2977082_2977508_+|hypothetical-protein	unknown	unknown	gnl|CDD|372980
NC_019693.1|WP_015148676.1|2965263_2967726_-|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl|CDD|273193
NC_019693.1|WP_044196985.1|2960801_2960933_+|photosystem-II-reaction-center-protein-Ycf12	unknown	unknown	gnl|CDD|237469
NC_019693.1|WP_044196983.1|2960143_2960521_-|YkgJ-family-cysteine-cluster-protein	unknown	unknown	gnl|CDD|308985
NC_019693.1|WP_015148687.1|2980665_2982063_+|YvcK-family-protein	unknown	unknown	gnl|CDD|376670
NC_019693.1|WP_015148674.1|2962775_2963243_-|response-regulator	unknown	unknown	gnl|CDD|381108
NC_019693.1|WP_015148686.1|2979473_2980256_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213228
NC_019693.1|WP_015148688.1|2982342_2982819_+|bifunctional-alanine-racemase/tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	unknown	unknown	gnl|CDD|223873
NC_019693.1|WP_044196994.1|2972510_2972996_-|allophycocyanin	unknown	unknown	gnl|CDD|381265
NC_019693.1|WP_156824054.1|2959514_2959925_-|UPF0016-domain-containing-protein	unknown	unknown	gnl|CDD|225030
NC_019693.1|WP_044195026.1|2962081_2962276_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148682.1|2974995_2975316_+|DUF1232-domain-containing-protein	unknown	unknown	gnl|CDD|225876
NC_019693.1|WP_015148689.1|2983337_2984681_-|dihydroorotase	unknown	unknown	gnl|CDD|236055
NC_019693.1|WP_015148677.1|2967941_2970203_-|DUF1565-domain-containing-protein	unknown	unknown	gnl|CDD|284923

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015148679.1|2970479_2971922_-|DUF1565-domain-containing-protein	gnl|CDD|284923	pfam07602, DUF1565, Protein of unknown function (DUF1565). These proteins share a region of homology in their N termini, and are found in several phylogenetically diverse bacteria and in the archaeon Methanosarcina acetivorans. Some of these proteins also contain characterized domains such as pfam00395 and pfam03422.	2.54193e-30
NC_019693.1|WP_015148675.1|2964115_2965267_+|PAS-domain-S-box-protein	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	2.27651e-21
NC_019693.1|WP_015148685.1|2977662_2979366_-|MCE-family-protein	gnl|CDD|178642	PLN03094, PLN03094, Substrate binding subunit of ER-derived-lipid transporter; Provisional.	8.62039e-32
NC_019693.1|WP_015148681.1|2973075_2974506_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl|CDD|129571	TIGR00479, 23S_rRNA_uracil1939-C5-methyltransferase_RlmD, 23S rRNA (uracil-5-)-methyltransferase RumA. This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification].	2.70986e-176
NC_019693.1|WP_044196996.1|2975698_2976748_+|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase	gnl|CDD|234858	PRK00892, lpxD, UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional.	3.16568e-150
NC_019693.1|WP_015148684.1|2977082_2977508_+|hypothetical-protein	gnl|CDD|372980	pfam14250, AbrB-like, AbrB-like transcriptional regulator. This family of DNA-binding proteins is likely to act as a transcriptional regulator. This family does not include E.coli AbrB, which belongs to pfam05145.	3.52763e-41
NC_019693.1|WP_044196983.1|2960143_2960521_-|YkgJ-family-cysteine-cluster-protein	gnl|CDD|308985	pfam03692, CxxCxxCC, Putative zinc- or iron-chelating domain. This family of proteins contains 8 conserved cysteines. It has in the past been annotated as being one of the complex of proteins of the flagellar Fli complex. However this was due to a mis-annotation of the original Salmonella LT2 Genbank entry of 'fliB'. With all its conserved cysteines it is possibly a domain that chelates iron or zinc ions.	4.24674e-12
NC_019693.1|WP_044196985.1|2960801_2960933_+|photosystem-II-reaction-center-protein-Ycf12	gnl|CDD|237469	PRK13686, PRK13686, photosystem II reaction center protein Ycf12.	2.2168e-10
NC_019693.1|WP_015148687.1|2980665_2982063_+|YvcK-family-protein	gnl|CDD|376670	pfam01933, UPF0052, Uncharacterized protein family UPF0052.	6.14788e-147
NC_019693.1|WP_015148674.1|2962775_2963243_-|response-regulator	gnl|CDD|381108	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains. This family is composed of response regulators (RRs) that are members of phytochrome-associated, light-sensing two-component signal transduction pathways such as Synechocystis sp. Rcp1, Tolypothrix sp. RcpA, and Agrobacterium tumefaciens bacteriophytochrome response regulator AtBRR. They are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. Also included in this family us Methanosaeta harundinacea methanogenesis regulatory protein FilR2, also a stand-alone RR. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.57165e-27
NC_019693.1|WP_015148686.1|2979473_2980256_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213228	cd03261, ABC_Org_Solvent_Resistant, ATP-binding cassette transport system involved in resistant to organic solvents. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	4.12975e-122
NC_019693.1|WP_015148688.1|2982342_2982819_+|bifunctional-alanine-racemase/tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	gnl|CDD|223873	COG0802, COG0802, Predicted ATPase or kinase [General function prediction only].	8.46871e-48
NC_019693.1|WP_044196994.1|2972510_2972996_-|allophycocyanin	gnl|CDD|381265	cd12125, APC_alpha, Allophycocyanin alpha subunit of the phycobilisome core. Phycobilisomes (PBSs) are the main light-harvesting complex in cyanobacteria and red algae. In general, they consist of a central core and surrounding rods and function to harvest and channel light energy toward the photosynthetic reaction centers within the membrane. They are comprised of phycobiliproteins/chromophorylated proteins (PBPs) maintained together by linker polypeptides. PBPs have different numbers of chromophores, and the basic monomer component (alpha/beta heterodimers) can further oligomerize to ring-shaped trimers (heterohexamers) and hexamers (heterododecamers). Stacked PBP hexamers form both the core and the rods of the PBS; the core is mainly made up by allophycocyanin (APC) while the rods can be composed of the PBPs phycoerythrin (PE), phycocyanin (PC) and phycoerythrocyanin (PEC).	2.11778e-101
NC_019693.1|WP_156824054.1|2959514_2959925_-|UPF0016-domain-containing-protein	gnl|CDD|225030	COG2119, COG2119, Predicted membrane protein [Function unknown].	4.1439e-29
NC_019693.1|WP_015148676.1|2965263_2967726_-|single-stranded-DNA-specific-exonuclease-RecJ	gnl|CDD|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	3.57921e-172
NC_019693.1|WP_015148682.1|2974995_2975316_+|DUF1232-domain-containing-protein	gnl|CDD|225876	COG3339, COG3339, Uncharacterized conserved protein [Function unknown].	2.34454e-21
NC_019693.1|WP_015148689.1|2983337_2984681_-|dihydroorotase	gnl|CDD|236055	PRK07575, PRK07575, dihydroorotase; Provisional.	0
NC_019693.1|WP_015148677.1|2967941_2970203_-|DUF1565-domain-containing-protein	gnl|CDD|284923	pfam07602, DUF1565, Protein of unknown function (DUF1565). These proteins share a region of homology in their N termini, and are found in several phylogenetically diverse bacteria and in the archaeon Methanosarcina acetivorans. Some of these proteins also contain characterized domains such as pfam00395 and pfam03422.	2.15456e-24

Protein sequences

>NC_019693.1|WP_015148679.1|2970479_2971922_-|DUF1565-domain-containing-protein
MMNKISSYPLVLITLSLLSAVTVTLGSQGERADGGKVLANVPTVQPSMNAQQRIIYVDPKRGNDSVSAGQSEENALRTITAALERAQSGTVIQLAAGRYHAGEVFPLKLQPGVILRGDESGRGDGVVITGGNTHLSRIWAGQNITILAGDSSQILGVTVTNPNPYGTGVWIENANAIVRNSTFTNNNREGIFVSGTAQPIIENNQFMYNGGNGISVTKESKGEIRRNVFQDTGFALAIGHNAAPVVAGNHIHQNRIGIVVTQAARPILEGNIIENNSDYGLVAIAESQPQIAASNTFRGNERENQLIARNPQGIPPTPDEPTGTQRAYFTCEPYGTNYATVAQQGYASIPQAMIVWKSSEVDLPENRCNEVTQKLNQKVTAYGGQLHKMLFATGRVNNDRVICLVKDLQDSCQPDNMLFTLSGFNASDPTQVLRQLIAFSVEGKGNPVQEFGEEAIAPLESVAHNLQPALGLWFVSGLTQ
>NC_019693.1|WP_015148677.1|2967941_2970203_-|DUF1565-domain-containing-protein
MNFKHQLLPTIVTVAVATWNPIALALSPAEVDAVAWQVSVLISPNLTQQGDAFLIEGEKTGSGVIVAREGNSYYVLTALHVVWKRGGFHAIAMPDGQVYYVDASENSPDIIPLGHPAGELGQTIAGLDLALLRVQSDRTYPLARTAPNPLQSGTPVFVNGWPNPDDLRQKIRDRQLVAGAIAEVTPPSDDGGYRLLYSNPTRSGMSGGGIFNANGELIGIHGRGRGVQNNCSTPEVNANNSCGMYIGEFLADSRVQSLQLSLNRNPIDPGMIHYGLTYASQIDRVNGSPVARSTPPPVIPPTITPETPQPSPPPVAEFPTPSPEAIAEAQTIYYVDPNQGTNAATAGLTPENPFRSISYALQGARPGTVIYLASGLYSARETFPLKLNPGVIIIGNESQQGEGVVIRGGGIASTRTAGRQNYTLFAGNSSQILGVTLTNPHSNGTAIWIEDTTTALIRNTTLMDNPREGILIGGNATPILEKNRFINNGGNGISITQQGAGEIRNNDFTNNGIGVAIAGMANPSITDNHIRGNRNGIVVTASATPTLQGNILENNQNYGILTLGLAPTPIAENNLFRNNGISNQLTARIQDWGLDIPPRTVTSTVFGCVEYEGGLATFAYTGKGSIPLPFLNWNHSASDSGLNRCRLVTSSLNKIVALMGQELSTMALSTGRVHNNNAVCLVDQSGEICQDSNLLFYLGGEEQRNPGEGLAPLLPFSWATAGNPVQQVETGAFAPLKDFAQRLAPEPGLWFTD
>NC_019693.1|WP_015148676.1|2965263_2967726_-|single-stranded-DNA-specific-exonuclease-RecJ
MVPSTAIRLPNHRWQIYPQKPELAQQLAEAVALPPILAQALIDRGIETVEAVQAFLDPESVNLPPPVDEFPDLALTVELLQKAIAKGSKIAICGDYDADGMTSTALLMRALRALGANVDYAIPSRMAEGYGINERIVREFHGEGVKIILTVDNGIAAVKPIALARELGMDAIITDHHELPDELPPATAILNPKLIREASPYRGVAGVGVAYILAICLAQKLGQSQSLIKPLRELLTLGTIADLAPLTGVNRRWVKRGLRQLPESELAGVQALIQVSGASSSGKTMKPDEIGFRLGPRINAVGRIGDPQVAIELLTTDDPGIALTRAMQCEQINQDRQQMCETIEAEAIAWVESSGMDYLGSRVLVVVQPGWHHGTIGIVASRLVERYGVPVFIGTYEDDRQEHIRGSARSIPEFHVFEAMQHCDRWLGKYGGHRAAGGFTLSAQNLDGFRQGLSEFAHGCLEPHHLKPAIAINALAEFEQIDLDLYREIDRLHPCGIENPSPVFWTPNVEVVDQRIVGKGHIKVTLESSTHSFHPNSSKIATPRRIQGIAWRWGDYFPLPRYIDVAYKLRENTWNGQTNVELELISARLPENEESRPREIIRPSVPSSPPVRRSLKTPPQPTVSESLPRTTVGVSASVVTPVIPEAPPVTVDPEWLSGISLPSLLTHLSGRVLFYGAGRPEIGETDCEIEWNFPKRPCDTLLLWTLPPSGTHLQWLLARGMPRQVYVYNHLPPLPSPMQLRSHLRDRLQDVGTQPLNLLHLGQELWVAPSTLLAALRELGDSYPEFPPTQTLDRELERLYRWYAFPPGKLAQINWRSPLH
>NC_019693.1|WP_015148675.1|2964115_2965267_+|PAS-domain-S-box-protein
MAMNQRIESLYHRSSEPSALQPNGELLPIAFKELGTASEELLVALEQLAEQQQQLVESQNQLEAERSRYQSLFEQAPHAYIALDSDGTITSVNRAATRLFDCTHRLLLHKPITILVPIEARREFREELKRRQQVEDDQDWPVRLYSPHREPFEAALTLSVERDAWGNIISTCLCIRDISEHQRAQAQKKKHTEDLFCDRPRHTFSKGENIPLQPDALWLICKGWVKLSTLTENNGEVMMGIAGKGIPFCRTLTALPIYQVKALSQTVELITIPHMEMAHSPHLAQLIAEGVTQRLQQSELLLCVCGRRRASDRLLALLQVLKTIIGEPVATGTRLSLRLTHQELAEASCTTRVTVTRLLSEFQHQGKITIDNTNHITLPEEYS
>NC_019693.1|WP_015148674.1|2962775_2963243_-|response-regulator
MNLVAKRKKILVVEDNLAYIHILKFAFEHSNWWAEAEIETVNDGKEAIDYLSRNQGNSGNHQGSDQLPHLILSDINMPHLSGLELLAWIRQTDHLKDLPFILMSSYIQPIELEIIQSLKANYYFIKPLTIPELLNNLNQTIKQLQLKEATVLEKL
>NC_019693.1|WP_044195026.1|2962081_2962276_-|hypothetical-protein
MHWTHWAEVYQTRDQLMKFVSGGGTGLRSLVRGSGKGRSPVTTIPKTVKSERQSVRLSNSLIQN
>NC_019693.1|WP_015148673.1|2961634_2961871_-|hypothetical-protein
MSQKWFAEQDSLSDAVEELAETTVSLGVISSFMVRYQGQQRRFYLPSESDSQPLTAEQAYLRLKQLMEESGLLSQISS
>NC_019693.1|WP_044196985.1|2960801_2960933_+|photosystem-II-reaction-center-protein-Ycf12
MDFLSSFASNLNLEVILQLTFVGLILIAGPVVIFLLAFRGGDM
>NC_019693.1|WP_044196983.1|2960143_2960521_-|YkgJ-family-cysteine-cluster-protein
MASWRCVKQCGACCHLDPEERPELAEYLSPEELALYLSMVGPDGWCIHLDQLNRECTIYDDRPRFCRVLPDVFEEMYGIEPEELDEFAIECCQQQIEAVHGDRSLEMLRFNQAVGVSLLELPPLD
>NC_019693.1|WP_156824054.1|2959514_2959925_-|UPF0016-domain-containing-protein
MSPVPSDAEACLERALTLPTALEQLSPSTPSPQTALKTRTPKARQGAWSVFASTFVTIFLAELGDKTQVATLLMTAESQSPWIVFAGAGSALVATSLLGVLLGRWLASRISPKTLEKSAGVVLLFVSAMLVWDILH
>NC_019693.1|WP_044196994.1|2972510_2972996_-|allophycocyanin
MSVVSQVILKADDELRYPTNGELTSLTQFFQTGQQRVRIATTLAENEKKIVEQASKRLWQKRPDFISPGGNAYGQRQRAQCLRDFGWYLRLATYGVLAGDKGPIEKIGIIGAREMYNALGVPMAGMAESIVCLKEASLALLSQEDATAAAPYFDYIVQAMS
>NC_019693.1|WP_015148681.1|2973075_2974506_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MSATNGQNNYAVGDRQDENWQQGCAIEVEIEDLSDTGDGVGRYQGRVVFVPDAVPGDRLLVRLVRVKPQYANGKLLEVLERSPNRIRPHCIVADKCGGCQWQSVAYSAQLQAKQNLVTQAIARIGGIEHPTVEPILPSPSPFGYRNKATYPLSRSSSGKVQAGYYEKNSHHLVNINQCPVQDSRLNPLLAEVKQDIQDRGWSIYNETEHRGNLRHLALQIGRRTGQILLTLVSANRKLMDIEAQAEEWLSRYPDLVGVCLNYNPNRTNAILGEETRCVAGQSYFVDEFAGVELQLRSDTFFQVNPETAEVLLETIASRLNLQGTERLVDAYCGIGTFTLPLAKRVQQAIGLEINPAAIAIAQENAQLNSLTNVSFHEGSVEKLLPQLESLGLPQGEKPDIVLLDPPRKGCDRSVLETLIQIAPQQIVYISCKPATLARDLKILCDSGIYRLSFLQPADFFPQTSHVEAVAFLVAQG
>NC_019693.1|WP_015148682.1|2974995_2975316_+|DUF1232-domain-containing-protein
MNNSIQSIYNWYRNTLRNPKYRWWIILGTVAYFFSPIDVAPDFIPVIGQLDDIALATLLVAELSQIAMDYFKARKGEVEESTNPVNTASTVGGSTVVDVEASSVNQ
>NC_019693.1|WP_044196996.1|2975698_2976748_+|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase
MKFSELVQKLAIHLPDSPTVSKGEDPEITGVAAVEEATPGSLSYIEGSKFANRIAGTAAAALILPMDPQLQQQASDRGIAWVATPEPRLLFAQAIALFYQPFRLSAGIHPTASIHPDATLGENVAIGAFVSIAQGVKIANQVCIHANVTLYPHAEIGEGTVLHSHCTIHERTRIGKGCTIHAGAVIGSEGFGFVPSRAGWVKMEQSGYTVLEDRVEVGCNSSIDRPAVGETRIGENTKIDNLVQIGHGCKIGKNCALAAQVGLAGGVKLGNNVILGGQVGVSNQVKVGDGAVASAKSGLHTDVPPGAIVSGFPAVPNKLWLKTVAISNRLPEMYQSLKQLQRLLGPKSN
>NC_019693.1|WP_015148684.1|2977082_2977508_+|hypothetical-protein
MSEIATTPLKGKALLQKVKELSHLPRRETAKRCGYYSKSKNEEYRVNLTDFYDAVLEARGIPLSPEGSKDGRGREATYRVSVHKNGQIVIGSTYTQSMGLKPGDEFEIKLGYKHIHLIQVDSSKNDFLNEDDEEFDEDDDD
>NC_019693.1|WP_015148685.1|2977662_2979366_-|MCE-family-protein
MRSSRKLREGSIGLLLLAGLGLFGGLILWLRGVGLGRESYTLVVSFPNVAGMQVGGPVRYRGVSVGRIANIIPGTNGVDVELIVSPASLVIPNAVLIEANQGGLIGETWVDINPLQALPPQIIKTTTPLASDCNTELILCNRERLEGQIGVNFDELIRGSMRFTNLFSDPAFFANLNALVKNSTVATAEITQLSREINVLTQSVERELGIFSTAALQSASALNTAAGQIGNTANQVGAISTQLGRTVNQYGAIAGDIRAATNQIGATANQYGAIAGDIRTATNQITAISNRYGAIAGDLQRTVNQIGAAAEEYGAVAGTFGASADRISLTLDRVGGTVEGLGGTAGELNLTAADLRTLIGSVNELVATNRGTLVTTLNNINTTSEQLRISAQQITPIVARVEQQLNQFEDSQLLANLDTLSITANELAVNASAASANLAQFTDTAISPSNLLSLQQTLDSARATFQNVQKITSDLEELTGDPALFESIRNILLILGDLLSSTEQLEEHARFAMALAPLSHTVSDPSLQSQLFPPASEEQSPEQLDSAVPPRSASPGPNPDKLTARNR
>NC_019693.1|WP_015148686.1|2979473_2980256_-|ABC-transporter-ATP-binding-protein
MSDPLIELKGVSKSFGRNVILNEVDLCIYRNEALSIIGPSGTGKSTILRIIAGLLQPDAGEVYVQGIRRDRWTDDLADPIGIGMVFQNAALFDSLNVDENVGFFLYEHSKLSRKQIRQLVTEKLEMVGLAGIGNKYPAELSGGMRKRVSFARAIMANPDDPTASPEVLLYDEPTAGLDPIASTVIEDLIRDLQAARGGCSTYVMVTHQDSTIRRTSDRIVFLFDGKVQWQGGIEEIDTTDNPLVRQFFSGSITGPIQLAG
>NC_019693.1|WP_015148687.1|2980665_2982063_+|YvcK-family-protein
MSIGLLKQAFHALKPDPLFRRGMRFNHWFKWLAPGLFVKRWLLLSAVGVLLTLLGLAIWVKLTPIFFAIQLTEKTLTQLATVIPSYISGPFVLLFGIFFILWGQTRTVGSITEVLRPGAEDELIDVLLHHRKLNRGAKIVVVGGGTGLSTLLRGLKTYSANITAIVTVADDGGSSGRLRRENGVLPPGDIRNCLAALADEEKLLTELFQYRFKAGNGLTGHSFGNLFLTAMSDISGDLERAIATSSKVLAVRGQVLPSTLCDVNLWAELADGRRIEGESSITEANGKIVKIGCTPANPPPLPKAIQAIREADFIILGPGSLYTSVIPNLLVPEIAEEIAKRNVPKIYVCNIMTQPGETDGYTVADHIKAIDLACGLKLFSSVLVQQQMPSAQSLIRYSQDNSHPVYVDRPKITELGRSVVFANVMQEDRETGYVRHDHQLLAQVLLRWYAHVHIKSSAGILSPAR
>NC_019693.1|WP_015148688.1|2982342_2982819_+|bifunctional-alanine-racemase/tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE
MSQSILKLVLPDADATKSLGFTLGQRCLPGTTILLEGDLGAGKTTLVQGIGSGLAIAESIVSPTFTLIVEYLEGRIPLYHLDLYRLDPTEVSGLNLESYWEGTETEPGLVAIEWAERLPYKPDDYLRLVLTHQEQGRQAELIPVGDFNLNVLMPLPRE
>NC_019693.1|WP_015148689.1|2983337_2984681_-|dihydroorotase
MRDHLLIRQARILQPDGEFLQGDVLIQEGKIRQIGPNIPGLDANPDPDAHLEVIDAVGLTLLPGVIDPQVHFREPGLEYKEDLFTASCACARGGVTSFLEMPNTRPLTTTQATLDDKLARGARSSLVNYGFFIGATAEHLPDLVEAHPACGIKIFMGSMKGPLLVDDQEALEAIFSQGDRLIAVHAEDRTRIEERRQQFSSRTDPAVHSEIQDTQAALIATKRALSLSKKYQRRLHILHLSTGDEALLLREDKPSWVTAEVTPQHLLLNTSAYDTIGTLAQMNPPLRSPRDNEILWQALLDGVIDFIATDHAPHTLEEKAQGYPNTPSGMPGVETSLPLMLTQAMQGRCTVPQVAHWMSTAVAKGYGIPNKGAIAPGYDADLVLVDLNTYRPVLREEVVSKCGWNPFEGWSLTGWPVVTIVGGQVVYDHGKLNTDIRGKALSFVRMG

Crispr_ID: NC_019693_27

• CRISPR_ID: NC_019693_27
• CRISPR_location: 3381174-3381261
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_27

Consensus_repeat	Method
CACCCTTGAAGGTGCGGGTTTTT	CRISPRCasFinder

spacers of NC_019693_27

>27.1|3381197|42|NC_019693|CRISPRCasFinder
GCTGGATTAGCCCGCGCAGGCACCGCTTCGTCCGTATAGCCC

CRISPR arrays and Neighbor proteins around NC_019693_27

CRISPR arrays

The CRISPR arrays of NC_019693_27

>merge|NC_019693|27|3381174-3381261|CRISPRCasFinder
CACCCTTGAAGGTGCGGGTTTTTGCTGGATTAGCCCGCGCAGGCACCGCTTCGTCCGTATAGCCCCACCCTTGAGGGTGCGGGTTTTT

>NC_019693|27|27|3381174-3381261|CRISPRCasFinder
CACCCTTGAAGGTGCGGGTTTTT	GCTGGATTAGCCCGCGCAGGCACCGCTTCGTCCGTATAGCCC
CACCCTTGAGGGTGCGGGTTTTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015148967.1|3386208_3386814_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238734
NC_019693.1|WP_015148970.1|3389284_3389926_+|50S-ribosomal-protein-L3	unknown	unknown	gnl|CDD|234564
NC_019693.1|WP_015148966.1|3385524_3386127_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238734
NC_019693.1|WP_015148958.1|3376248_3376671_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148961.1|3377437_3380602_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|223715
NC_019693.1|WP_015148955.1|3368640_3368901_+|hypothetical-protein	unknown	unknown	gnl|CDD|226580
NC_019693.1|WP_015148959.1|3376774_3376963_+|CPXCG-motif-containing-cysteine-rich-protein	unknown	unknown	gnl|CDD|379524
NC_019693.1|WP_015148972.1|3390616_3390925_+|50S-ribosomal-protein-L23	unknown	unknown	gnl|CDD|376308
NC_019693.1|WP_015148968.1|3387002_3387608_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238734
NC_019693.1|WP_015148960.1|3376983_3377430_+|SRPBCC-family-protein	unknown	unknown	gnl|CDD|176862
NC_019693.1|WP_015148964.1|3383201_3384425_-|(Fe-S)-binding-protein	unknown	unknown	gnl|CDD|372225
NC_019693.1|WP_015148971.1|3389991_3390624_+|50S-ribosomal-protein-L4	unknown	unknown	gnl|CDD|235404
NC_019693.1|WP_015148969.1|3387802_3388267_-|NAD(P)H-quinone-oxidoreductase-subunit-N	unknown	unknown	gnl|CDD|371790
NC_019693.1|WP_015148953.1|3367353_3367848_+|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|225113
NC_019693.1|WP_015148965.1|3384633_3385179_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015148954.1|3367870_3368614_+|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224051
NC_019693.1|WP_015148963.1|3381264_3383112_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|226372
NC_019693.1|WP_015148957.1|3374496_3376140_+|radical-SAM-protein	unknown	unknown	gnl|CDD|188475
NC_019693.1|WP_015148956.1|3369363_3372543_-|S-layer-family-protein	unknown	unknown	gnl|CDD|368641
NC_019693.1|WP_015148962.1|3380894_3381140_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015148970.1|3389284_3389926_+|50S-ribosomal-protein-L3	gnl|CDD|234564	PRK00001, rplC, 50S ribosomal protein L3; Validated.	4.18321e-119
NC_019693.1|WP_015148966.1|3385524_3386127_-|VWA-domain-containing-protein	gnl|CDD|238734	cd01457, vWA_ORF176_type, VWA ORF176 type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses. In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. The members of this subgroup are Eubacterial in origin and have a conserved MIDAS motif. Not much is known about the biochemistry of these.	1.33267e-89
NC_019693.1|WP_015148967.1|3386208_3386814_-|VWA-domain-containing-protein	gnl|CDD|238734	cd01457, vWA_ORF176_type, VWA ORF176 type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses. In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. The members of this subgroup are Eubacterial in origin and have a conserved MIDAS motif. Not much is known about the biochemistry of these.	3.02554e-100
NC_019693.1|WP_015148961.1|3377437_3380602_-|PAS-domain-S-box-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.62723e-43
NC_019693.1|WP_015148955.1|3368640_3368901_+|hypothetical-protein	gnl|CDD|226580	COG4095, COG4095, Uncharacterized conserved protein [Function unknown].	1.12238e-14
NC_019693.1|WP_015148959.1|3376774_3376963_+|CPXCG-motif-containing-cysteine-rich-protein	gnl|CDD|379524	pfam14255, Cys_rich_CPXG, Cysteine-rich CPXCG. This family of proteins is found in bacteria. Proteins in this family are approximately 60 amino acids in length. There are 5 conserved cysteines which occur in a CPXCG motif and a DCXXCCXP motif.	7.35535e-18
NC_019693.1|WP_015148972.1|3390616_3390925_+|50S-ribosomal-protein-L23	gnl|CDD|376308	pfam00276, Ribosomal_L23, Ribosomal protein L23.	3.26396e-41
NC_019693.1|WP_015148968.1|3387002_3387608_-|VWA-domain-containing-protein	gnl|CDD|238734	cd01457, vWA_ORF176_type, VWA ORF176 type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses. In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. The members of this subgroup are Eubacterial in origin and have a conserved MIDAS motif. Not much is known about the biochemistry of these.	1.77016e-93
NC_019693.1|WP_015148960.1|3376983_3377430_+|SRPBCC-family-protein	gnl|CDD|176862	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	8.9182e-52
NC_019693.1|WP_015148964.1|3383201_3384425_-|(Fe-S)-binding-protein	gnl|CDD|372225	pfam12617, LdpA_C, Iron-Sulfur binding protein C terminal. This domain family is found in bacteria and eukaryotes, and is typically between 179 and 201 amino acids in length. The family is found in association with pfam00037. LdpA (light-dependent period) plays a role in controlling the redox state in cyanobacteria to modulate its. circadian clock. LdpA is a protein with Iron-Sulfur cluster-binding motifs.	2.03544e-117
NC_019693.1|WP_015148969.1|3387802_3388267_-|NAD(P)H-quinone-oxidoreductase-subunit-N	gnl|CDD|371790	pfam11909, NdhN, NADH-quinone oxidoreductase cyanobacterial subunit N. The proton-pumping NADH:ubiquinone oxidoreductase catalyzes the electron transfer from NADH to ubiquinone linked with proton translocation across the membrane. It is the largest, most complex and least understood of the respiratory chain enzymes and is referred to as Complex I. The subunit composition of the enzyme varies between groups of organisms. Complex I originating from mammalian mitochondria contains 45 different proteins, whereas in bacteria, the corresponding complex NDH-1 consists of 14 different polypeptides. homologs of these 14 proteins are found among subunits of the mitochondrial complex I, and therefore bacterial NDH-1 might be considered a model proton-pumping NADH dehydrogenase with a minimal set of subunits. Escherichia coli NDH-1 readily disintegrates into 3 subcomplexes: a water-soluble NADH dehydrogenase fragment (NuoE, -F, and -G),the connecting fragment (NuoB, -C, -D, and -I), and the membrane fragment (NuoA, -H, -J, -K, -L, -M, -N). In cyanobacteria and their descendants, the chloroplasts of green plants, the subunit composition of NDH-1 remains obscure. The genes for eleven subunits NdhA-NdhK, homologous to the NuoA-NuoD and NuoH-NuoN of the E. coli complex, have been found in the genome of Synechocystis sp. PCC 6803 which has a family of 6 ndhD genes and a family of 3 ndhF genes. Two reported multisubunit complexes, NDH-1L and NDH-1M, represent distinct NDH-1 complexes in the thylakoid membrane of Synechocystis 6803 -cyanobacterium. NDH-1L was shown to be essential for photoheterotrophic cell growth, whereas expression of NDH-1M was a prerequisite for CO2 uptake and played an important role in growth of cells at low CO2. Here we report the subunit composition of these two complexes. Fifteen proteins were discovered in NDH-1L including NdhL, a new component of the membrane fragment, and Ssl1690 (designated as NdhO), a novel peripheral subunit. The cyanobacterial NDH-1 complex contains additional subunits, NdhM and NdhN, compared with the minimal set of the bacterial enzyme and these seem to be specific for thylakoid-located NDH-1 of photosynthetic organisms.	2.71037e-97
NC_019693.1|WP_015148953.1|3367353_3367848_+|GAF-domain-containing-protein	gnl|CDD|225113	COG2203, FhlA, FOG: GAF domain [Signal transduction mechanisms].	8.25883e-15
NC_019693.1|WP_015148971.1|3389991_3390624_+|50S-ribosomal-protein-L4	gnl|CDD|235404	PRK05319, rplD, 50S ribosomal protein L4; Provisional.	3.07865e-103
NC_019693.1|WP_015148954.1|3367870_3368614_+|amino-acid-ABC-transporter-ATP-binding-protein	gnl|CDD|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	3.37058e-157
NC_019693.1|WP_015148963.1|3381264_3383112_-|AAA-family-ATPase	gnl|CDD|226372	COG3854, SpoIIIAA, ncharacterized protein conserved in bacteria [Function unknown].	1.75292e-122
NC_019693.1|WP_015148957.1|3374496_3376140_+|radical-SAM-protein	gnl|CDD|188475	TIGR03960, radical_SAM_domain_protein, radical SAM family uncharacterized protein. This model describes a radical SAM protein, or protein region, regularly found paired with or fused to a region described by TIGR03936. PSI-BLAST analysis of TIGR03936 suggests a relationship to the tRNA pseudouridine synthase TruA, suggesting that this system may act in RNA modification. [Unknown function, Enzymes of unknown specificity].	4.64074e-102
NC_019693.1|WP_015148956.1|3369363_3372543_-|S-layer-family-protein	gnl|CDD|368641	pfam05860, Haemagg_act, haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins.	1.91643e-24

Protein sequences

>NC_019693.1|WP_015148962.1|3380894_3381140_+|hypothetical-protein
MKTDFNFPGKYLMGPVVFRPSFNEQSEVINANQAWSLFFTAGQEDKALGFNTEAGRFFTNLLMAIAVSGIIYSLFFSSNIG
>NC_019693.1|WP_015148961.1|3377437_3380602_-|PAS-domain-S-box-protein
MTTCSINLQRCEENLLNWKSAVNHTAIVIETDDRGRITEVNDKFIEISGYSREESLDRTPALVDSGLHPAEFFTQLWETISQGQVWRGEIKNKRKDGSIYWVDTTITPILNAEGIPHKYIALQFDITSQKQMEEKLTFTQRRFQQLAANLPGVIYQFLMRPDGAVFFPYMSPGCQDFFEINAESIENNAQVLLNLIHPDDFPNFYRSVAISAETLEPWHWEGRVINPSGKVVWIEGHSRPEQQENGDILWDGLLIEITERKIAQEALRQSEQRLGLHFQQTPLAVIEWDLNFKVMDWNPAAEKMFGYSKSEALNHHAVELLVPESAREQVDQVFQALLQQTGGTRSTNENFTKSGEIIVCEWYNTPLIDPDGTAIGVASLVEDITERQHYQDALKAANEALEHRVEERTEQLQEAIAKLQGEMASRELAEEKYRSIFENAIMGIFQTTQEGEYISANPALARIYGYESTQELMQELHNVDHQLYVEPNRRDQFIEAIAQHGKIADFESQVYCKNGEIIWIAENARAVRDETGTLLYYEGTVEEITKRKHTEAALRRSEERLQEKALREALLNQLTEQIRQSLDLETILATTVQEIRELLQIELCYFSWYRPNGMPQEGVRSRLQQQDCLVLDWEAVKEARSPGVVSPLGFYAVSESWSHQCLQLQPIRIDAVASYPNRTVVEIFRAWGFKSVLCLPLQTHSGEVGVLSCVHCSKERAWNESEVVLMGSISDRLTIAIDQAQLYAQSRAAAQQARDQAQRLEQALYQLQETQTQLIQTEKMSSLGQMVAGIAHEINNPITFIHGNTIHASNYFKEILPLIELYQHYYPKPVPEICDLLEELDLAFILDDLPKALHSMKLGTERIRQIVLSLRNFSRLDESQKKPVDIHEGIDNTVLILQHRLSQIQVVKKYGKLPLIECYPGQLNQVFMNILANAIDALEEAEGLATKPGNGKFPTPNSPVLNFSPTISIHTELTPDELVVIRIKDNGPGLTETVKNRLFDPFFTTKPVGKGTGLGLSISYQIIVEKHQGILDCQSQPGWGAEFVIKIPIKTGTK
>NC_019693.1|WP_015148960.1|3376983_3377430_+|SRPBCC-family-protein
MLHFKYSSLINAPVEVVWNFHERPDILQQLTPPWQPVEIVRREGGLGVGAISEFKIFLGPIPVLWLAQHTVCEPYQLFIDEQVEGPMDQWIHRHEFIRENGKTRLIDAIDYAIPGGWIPDLMLGWFVDARLRDMFRYRHEVTQRECSL
>NC_019693.1|WP_015148959.1|3376774_3376963_+|CPXCG-motif-containing-cysteine-rich-protein
MQTTAEYYCAYCGEDNVIFVDLSAGSYQSYVEDCQICCQPNVLYLQIDEETLDVEITSDPES
>NC_019693.1|WP_015148958.1|3376248_3376671_+|hypothetical-protein
MNLNQNAWKLSVAIAGALFCYTPTATAQLTPTPVLETAEFSHPMPVEIAQQRFCPDGAGGTPLVNFYETDNFWVYICRADRLYYYGVEKGSGSSITLPVEVEEGTGYVAVNGEYTYIVNGLSLSIYRGNTLLQEDWVYRE
>NC_019693.1|WP_015148957.1|3374496_3376140_+|radical-SAM-protein
MTPSIFDAEHLLFIPATADADAIPVIYAFPNEYTVGITSLGYQIVWATLATRGDLQVSRLFTDLHEPLPGEPELLGFSVSWELDYVNILGLLESLDIPIRASNRQESHPLIFGGGPVLTANPEPFADFFDVILLGDGENLLGEFVDGYQQVRKAGRLQQLRHLAQIPGVYVPSLYEVTYHSPEGAIASIHPIDSDIPETVAKQTYRGNVLSTSSVVTEKAAWPDIFMVEVVRSCPEMCRFCLASYLTLPFRTASLETSLIPAIERGLQVTRRIGLLGASVTQHPEFNQLLDYLNQPQFEDVRLSIASVRTNTVTPELAQTLANRGTKSLTIAIESGSERVRKIVNKKLENQEITQAAVNAKAGGLTGLKLYGMSGVPGEELEDLEATVQLLQSLKKSAPGLRLTFGCSTFVPKAHTPFQWFGVNPQAEKRLKKLQKELGKSGIEFRPESYNWSVIQALISRGDRRLSSLLELVRNYGETLGSYRRAFKELRGTLPDLDFYVHENWESTQILPWNHILGPLPVSTLQKHLAEATSYFPAAKKIISPVS
>NC_019693.1|WP_015148956.1|3369363_3372543_-|S-layer-family-protein
MKIWWRFGSSQGFRTSALWGIAVLLSTVPFNLAQAQILPDSTLPEASRVTGNGNTFTIEGGTVGSGNLFHSFSEFSLPTGLEAHFNNSLEIQNIFTRVTGAKISNIDGLIRANGTANLFFLNPNGIIFGPNARLQIGGSFFTSSAESLLFDSGAEFSASNPTETPLLTLRVPVGLQMGSNPGEIQVNGAGISDTLPTDNLGLSVAPGQTLGFIGGNVTFSGGIATAPSGRIEVGSLRNGIAEIVPLPLGYKLQYDALASEFQDIKLLAGASLFSPSLFVNPDSEIQITGRSLNLNASQIASVTSQEANGTPINIRTSESVQMGGTLNTIFPYSSWIVTQVGENATGSGGDIAIASPKIALSDGAKIQTISEGSGNAGNIAIAAPESLEIIGFAIPPNLVTDPTQITNEILFAQYTNSRISSENYASGAGGNVRVSTGNLTAGGGGQIATLVGVDATGKGGEITVDADTIAADGVLFFNPIAFSGIGSYTLGNGVGGDVNLVARQVNLNNGAEIFSWSQGTQPGGNLRANISESFVATEVNPLAPLLFSGLVTYTIGEANSGNLELSADRISLLNGGKIATVALITQLSNNPTSQVPAGNSGDVTVTADTIQLSSTSFLQPESSSLIATIMLGSGNAGDVSVVTRQLSITEGATVASSSVASFLGLGLPLPGAGSGNGGNVTVQASELIEVLGENPFYPQNSFLGALSVGTGNTGNVFVSSPRILLKDGGSIFSSTTATGNSGQLRVEAGDIRIEGVTPRGTVSQLGANAIVFPEEFQQIYFLPALPTGNTGTVIVNADRITLSDGGTLSVQHPGTGNAGTLQVNVDRLTLDRGGNINATTAFGFGGNVELHVADSLQLSNGSQITVAALGDLGDGGNLQIDSDTIAALSQSQISANAVGGNGGNINIRTDGLFLSPNSQITASSQFGLDGEIAIKTPDATSADGLVDLSAEFSDPSGQIVAGCAADEGNQLIVTGRGGLPEDPTQPFMGSTIWHDLRPVPNLADVEKLGDRSSLPQPSQQRDRTPPVVEAKGWTRNSQGHLVLTAASPNPDLFIPHFCR
>NC_019693.1|WP_015148955.1|3368640_3368901_+|hypothetical-protein
MNEQTITIIGLLAGTLTTLAFVPQVLQTWKSKSTKDVSLNTFLMFCTGIFLWLIYGLFKQDIAIILANFITFILASIILGLKLKYK
>NC_019693.1|WP_015148954.1|3367870_3368614_+|amino-acid-ABC-transporter-ATP-binding-protein
MTLDKQPIIIAKDVQKWYGQYHALRGVSLTIDPGEVVVIMGPSGSGKSTFIRTFNALEDYQKGRIEIDGIELSNDLKNIDNIRREVGMVFQQFNLFPHLTVLQNVTLAPKWVRRWSKVKAEEVGMQLLERVGILEQARKYPGQLSGGQQQRVAIARALAMQPKIMLFDEPTSALDPEMVREVLEVMRDLATSGMTMVVVTHEVGFAREVADRVVFMDSGTVIEVATPTNFFQNPQEERTRQFLSQIL
>NC_019693.1|WP_015148953.1|3367353_3367848_+|GAF-domain-containing-protein
MSDWSLRQVADRLAKTLNQDLLIRQTTLELREILNVNRILLYYFYSPWKGQVTFESVSAPQFSIIGQSGPDQCFGDEYAALYLQGRVRAISNIETEPINECHREFLRTLQVKANLVVPVLSPIGLWGLLVAHHCEDTRLWSLDDIKRMKNAAETLGTAATIRDS
>NC_019693.1|WP_015148963.1|3381264_3383112_-|AAA-family-ATPase
MVNSQGNQPIDNPIQPQAQSGVENVDLGRTQITDDLSQLLEILPETIREHLTNHSSLSNLIEVVMDLGRLPEARFPNKAEYISDIPVTRSDLKYAIERVGHFSGDNRAGIEQTLHRISAIRNRTGEIIGLTCRVGRSVFGTIHMIRDLVESGQSILMLGRPGVGKTTALREIARVLADELHKRVVIIDTSNEIAGDGDIPHPAIGRARRMQVAAPEFQHKVMIEAVENHMPEVIVIDEIGTELEALAARTIAERGVQLVGTAHGNQIENLIKNPTLCDLVGGIQSVTLGDEEARRRGSQKTVLERKAPPTFEIAVEMSERKRWVVHERVAETVDSLLRGRQPDLQVRTVSESGKVTITKELQPQNSTTTKTTAAVRPFGSAGLRASGKMQPLPVQTLPELGRRSQAVPEEKSFEQMLNESLYPGDRFASAADYGFEEISPLAGPNGEDLPLHVYPYGVSRHQLDQVIRTLALPVVVTKDIDSADVVLAVRSHVKNHSKLRQMSKNRQVPIFTINSSSVPKIAHSLRRMLHLDEGSTPEISDVSLFAQSGSDDEIEALEEARLAVEQIVIPKGQPVELLPRGGQVRKMQHELVEHYRLKSCSFGDEPNRRLRIYPA
>NC_019693.1|WP_015148964.1|3383201_3384425_-|(Fe-S)-binding-protein
MSNLNDPLTSLSEGHWFKLICGASFQHLQFVRNITLAYCLAGADCIDVAADPAVIAAANEAIEKAVTLGQGTQQRGSRHPFVKKGVPRPLLMVSLNDGEDPHFRKAEFNPQNCPPDCPRPCESICPAQAIAFPQSALTLAPKPGNSSFKTTQHSPEFQQKAGVIEDRCYGCGRCLPVCPIGQIVTRSYVSTPTAIAPSVLSKGVNAVEIHTQVGRIEDFKRLWSAVAPSVNQLKVVAISCPDGENLVDYLWSIYHAISPVPCALIWQTDGRPMSGDIGIGTTRAAIKLGQKVLAAGLPGFVQLAGGTNHHTVSKLKSMGLLRQGRVNPRDHQTDSYLSGVAYGSYARVLLSPILERVEQQQGESFSGSYCLEDCPDLLWEAVSLADSLVSEIKFGLQLQNNTHNTMP
>NC_019693.1|WP_015148965.1|3384633_3385179_-|hypothetical-protein
MDPIEKLLEQIKAETENPGPKLPDQGKANPAPKAANSPPVNPPKLMYNLDSLLEKVESEAKPPNVQPSVNVQPIALESTSPGLGGHLDQLFGDVKQEFEAQEQAEQLKREQERQEEAKKLERLKQKQREGLAKRAQEWLKKLDPYSDEGFWFGQFAEHYSSKLEAAIAYLEATPSQKRGEG
>NC_019693.1|WP_015148966.1|3385524_3386127_-|VWA-domain-containing-protein
MLDNRDYTLIVDKSGSMMTPDGTGSKTRWSSAEESTFALAAKCEQLDPDGITVYLFSGRFQRYDNVTSAKVAQIFKENEPSGRTDLASVLQDAVNHYFQNKASGAAKSGETILVITDGEPDDRKAVMKVIIEATRQMERDEELAISMIQVGNDTQATRFLKALDDELEGVGAKFDIVDTITIDEMEDYTLSEVLLKAISD
>NC_019693.1|WP_015148967.1|3386208_3386814_-|VWA-domain-containing-protein
MVENRDYTLIIDKSGSMSTPDQPGGKTRWQVAQESTLALARKCEEFDPDGITIYLFSGRFQRYDNVTAAKVDQIYQENEPMGRTNLAAVLQDAVNQYFQRKSSGQTKPNGETILVVTDGEPDDRKAVMEVIIKATRQMDRDEELAMSFIQVGNDAQASRFLKALDDDLQGVGAKFDIVDTITMDDMEETPLKEVLLRAIVD
>NC_019693.1|WP_015148968.1|3387002_3387608_-|VWA-domain-containing-protein
MLDNRDYTLIIDKSGSMSTPDQRGGRTRWQEAQESTLALARKCEELDPDGITVYVFSGRFKRYDNVTAAKVEQIFQENEPAGRTDLAGVLQDALNDYFKRKSAGQTQLNGETILAITDGEPDDRKAVMKVIIEASRRIDKDEELAISFIQIGNDRTATQFLKALDDDLINAGAKFDIVDTLTIDDMEEMTLTEVLMNAIID
>NC_019693.1|WP_015148969.1|3387802_3388267_-|NAD(P)H-quinone-oxidoreductase-subunit-N
MALIITGKKFIRDLEQNGSLALYVPLEGGFEGRYQRRVRAAGYVTVNLSARGLGDLAAYLTGVHGVRPPHLGKKDIRTYFIPPIVSSQLEQLPPKAKGLVVWLIDGIVLSNQELSYLTELSKIEPRVKVVVEVGGDRTVTWNPLKDLLVPARAS
>NC_019693.1|WP_015148970.1|3389284_3389926_+|50S-ribosomal-protein-L3
MAVGILGTKLGMTQVFDEEGRAIPVTVVQAGPCTVTQIKSKQTDGYSAIQVGYGETTTKAINKPELGHLVKSSAPPLRHLREYRIDDVSSFELGQQMTVEGFTANQIVDVTGITIGRGFAGYQKRHNFKRGPMSHGSKNHRAPGSTGAGTTPGRVYPGKRMAGRLGGSQITTRKLEIVRVDAEKNLLLIKGALPGKPGALLNIKPANYVGRAK
>NC_019693.1|WP_015148971.1|3389991_3390624_+|50S-ribosomal-protein-L4
MVNCVVRNWEGEQVAEASIDLRVASEENAKHILHRAVTRQLNQGRQGTASTKTRAEVRGGGRKPWRQKGTGRARAGSIRSPLWRGGGVIFGPKPRDYDVKMNRKERRLALRTALISRSEDLIVVEEFADKLPRPKTKDLLSAIARWGVEPDSKVLLIVDQRDDNVYLSARNVENIKLIAVNQLNVYDLVAADKIVTTAAALAKVQEVYGG
>NC_019693.1|WP_015148972.1|3390616_3390925_+|50S-ribosomal-protein-L23
MAEDNLRKLADLVRTPIVTEKATLLMEQNKYVFDVDAKSTKPQIKAAIEHLFEVKVVSVNTMHRPPKKRRVGKFVGYKPHYKRAIVTLAEGDSLQNIFFPEV

Crispr_ID: NC_019693_28

• CRISPR_ID: NC_019693_28
• CRISPR_location: 3497270-3497449
• CRISPR_type: Orphan
• Repeat_type: NA:I-D,II-B
• Spacer_info: 2 spacers

Consensus repeat of NC_019693_28

Consensus_repeat	Method
AGTTTCAATCC--------------------CTGATAGGGATTAGAGGTTATTGAGACC	PILER-CR
GTTTCAATCCCTGATAGGGATTAGAGGTTATTGAGAC	CRISPRCasFinder

spacers of NC_019693_28

>28.1|3497309|32|NC_019693|PILER-CR
TGATTCAGAACGATATTATATTGATTTTGCTG
>28.2|3497380|32|NC_019693|PILER-CR
GTACACCTATCGCCCCAGGGGAGACCTCCTCA
>28.3|3497307|34|NC_019693|CRISPRCasFinder
ATGATTCAGAACGATATTATATTGATTTTGCTGA
>28.4|3497378|34|NC_019693|CRISPRCasFinder
CGTACACCTATCGCCCCAGGGGAGACCTCCTCAA

CRISPR arrays and Neighbor proteins around NC_019693_28

CRISPR arrays

The CRISPR arrays of NC_019693_28

>merge|NC_019693|28|3497270-3497449|PILER-CR,CRISPRCasFinder
GTTTCAATCCCTGATAGGGATTAGAGGTTATTGAGACATGATTCAGAACGATATTATATTGATTTTGCTGAGTTTCAATCCCTGATAGGGATTAGAGGTTATTGAGACCGTACACCTATCGCCCCAGGGGAGACCTCCTCAAGTTTCAATCCCTGATAGGGATTAGAGGTTATTGAGACC

>NC_019693|28|2|3497270-3497449|PILER-CR
GTTTCAATCCCTGATAGGGATTAGAGGTTATTGAGACAT	GATTCAGAACGATATTATATTGATTTTGCTGA
GTTTCAATCCCTGATAGGGATTAGAGGTTATTGAGACCG	TACACCTATCGCCCCAGGGGAGACCTCCTCAA
GTTTCAATCCCTGATAGGGATTAGAGGTTATTGAGACC

>NC_019693|28|28|3497270-3497448|CRISPRCasFinder
GTTTCAATCCCTGATAGGGATTAGAGGTTATTGAGAC	ATGATTCAGAACGATATTATATTGATTTTGCTGA
GTTTCAATCCCTGATAGGGATTAGAGGTTATTGAGAC	CGTACACCTATCGCCCCAGGGGAGACCTCCTCAA
GTTTCAATCCCTGATAGGGATTAGAGGTTATTGAGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015149067.1|3499217_3499511_-|HNH-endonuclease	unknown	unknown	gnl|CDD|225724
NC_019693.1|WP_015149057.1|3482152_3482461_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149066.1|3497504_3498956_-|IS66-family-transposase	unknown	unknown	gnl|CDD|376980
NC_019693.1|WP_015149069.1|3501471_3502602_+|IS701-family-transposase	unknown	unknown	gnl|CDD|376573
NC_019693.1|WP_015146995.1|3503106_3504729_-|IS1634-family-transposase	unknown	unknown	gnl|CDD|227708
NC_019693.1|WP_015149056.1|3481359_3481995_+|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	unknown
NC_019693.1|WP_156823840.1|3499059_3499296_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149061.1|3490520_3493037_-|CHASE2-domain-containing-protein	unknown	unknown	gnl|CDD|226703
NC_019693.1|WP_052315743.1|3493070_3493976_-|DUF1822-family-protein	unknown	unknown	gnl|CDD|370155
NC_019693.1|WP_015149058.1|3482582_3486905_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|225387
NC_019693.1|WP_156823841.1|3500730_3500901_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149055.1|3472580_3481184_+|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173789
NC_019693.1|WP_044195134.1|3504753_3505227_-|hypothetical-protein	unknown	unknown	gnl|CDD|143586
NC_019693.1|WP_015149060.1|3489617_3490496_-|DUF928-domain-containing-protein	unknown	unknown	gnl|CDD|368720
NC_019693.1|WP_015149072.1|3506669_3507866_-|DUF4157-domain-containing-protein	unknown	unknown	gnl|CDD|379338
NC_019693.1|WP_015149063.1|3494000_3494612_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149064.1|3495186_3495510_+|membrane-protease-regulatory-membrane-protein	unknown	unknown	gnl|CDD|376684
NC_019693.1|WP_044195128.1|3486850_3489562_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|227328
NC_019693.1|WP_156824047.1|3505461_3506658_+|ISL3-family-transposase	unknown	unknown	gnl|CDD|376574
NC_019693.1|WP_015149068.1|3499875_3500580_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015149067.1|3499217_3499511_-|HNH-endonuclease	gnl|CDD|225724	COG3183, COG3183, Predicted restriction endonuclease [Defense mechanisms].	0.000405216
NC_019693.1|WP_052315743.1|3493070_3493976_-|DUF1822-family-protein	gnl|CDD|370155	pfam08852, DUF1822, Protein of unknown function (DUF1822). This family of proteins are functionally uncharacterized.	1.33023e-63
NC_019693.1|WP_015149066.1|3497504_3498956_-|IS66-family-transposase	gnl|CDD|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	1.75586e-39
NC_019693.1|WP_015149069.1|3501471_3502602_+|IS701-family-transposase	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	9.45503e-08
NC_019693.1|WP_044195134.1|3504753_3505227_-|hypothetical-protein	gnl|CDD|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	6.46554e-07
NC_019693.1|WP_015149061.1|3490520_3493037_-|CHASE2-domain-containing-protein	gnl|CDD|226703	COG4252, COG4252, Predicted transmembrane sensor domain [Signal transduction mechanisms].	1.90146e-102
NC_019693.1|WP_015146995.1|3503106_3504729_-|IS1634-family-transposase	gnl|CDD|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	2.28857e-66
NC_019693.1|WP_015149058.1|3482582_3486905_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl|CDD|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	2.83267e-87
NC_019693.1|WP_015149055.1|3472580_3481184_+|S8-family-serine-peptidase	gnl|CDD|173789	cd04059, Peptidases_S8_Protein_convertases_Kexins_Furin-like, Peptidase S8 family domain in Protein convertases. Protein convertases, whose members include furins and kexins, are members of the peptidase S8 or Subtilase clan of proteases. They have an Asp/His/Ser catalytic triad that is not homologous to trypsin. Kexins are involved in the activation of peptide hormones, growth factors, and viral proteins. Furin cleaves cell surface vasoactive peptides and proteins involved in cardiovascular tissue remodeling in the TGN, at cell surface, or in endosomes but rarely in the ER. Furin also plays a key role in blood pressure regulation though the activation of transforming growth factor (TGF)-beta. High specificity is seen for cleavage after dibasic (Lys-Arg or Arg-Arg) or multiple basic residues in protein convertases. There is also strong sequence conservation.	6.12855e-71
NC_019693.1|WP_015149060.1|3489617_3490496_-|DUF928-domain-containing-protein	gnl|CDD|368720	pfam06051, DUF928, Domain of Unknown Function (DUF928). Family of uncharacterized bacterial protein.	6.69248e-66
NC_019693.1|WP_015149072.1|3506669_3507866_-|DUF4157-domain-containing-protein	gnl|CDD|379338	pfam13699, DUF4157, Domain of unknown function (DUF4157). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 80 amino acids in length. This domain contains an HEXXH motif that is characteristic of many families of metallopeptidases. However, no peptidase activity has been shown for this domain.	9.34046e-38
NC_019693.1|WP_015149064.1|3495186_3495510_+|membrane-protease-regulatory-membrane-protein	gnl|CDD|376684	pfam01957, NfeD, NfeD-like C-terminal, partner-binding. NfeD-like proteins are widely distributed throughout prokaryotes and are frequently associated with genes encoding stomatin-like proteins (slipins). There appear to be three major groups: an ancestral group with only an N-terminal serine protease domain and this C-terminal beta sheet-rich domain which is structurally very similar to the OB-fold domain, associated with its neighboring slipin cluster; a second major group with an additional middle, membrane-spanning domain, associated in some species with eoslipin and in others with yqfA; a final 'artificial' group which unites truncated forms lacking the protease region and associated with their ancestral gene partner, either yqfA or eoslipin. This NefD, C-terminal, domain appears to be the major one for relating to the associated protein. NfeD homologs are clearly reliant on their conserved gene neighbor which is assumed to be necessary for function, either through direct physical interaction or by functioning in the same pathway, possibly involve with lipid-rafts.	1.22281e-10
NC_019693.1|WP_044195128.1|3486850_3489562_+|CHAT-domain-containing-protein	gnl|CDD|227328	COG4995, COG4995, Uncharacterized protein conserved in bacteria [Function unknown].	8.0682e-109
NC_019693.1|WP_156824047.1|3505461_3506658_+|ISL3-family-transposase	gnl|CDD|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	4.81102e-70

Protein sequences

>NC_019693.1|WP_015149064.1|3495186_3495510_+|membrane-protease-regulatory-membrane-protein
MSSASVHRKNWFVAIVRLLFFKNHSETGHHYVTPNPEFLTSVEQEAIVDEAILPRKVGRVYFGGSWWPARCDRAITLSPGETVYVVGRHNITLLVEPESFIKPTFRR
>NC_019693.1|WP_015149063.1|3494000_3494612_-|hypothetical-protein
MDEAIQNLAMEAKRHPPQSKERQLALTKLIEAISYSGKLCRPRQGQFSHVYEDIYAEALSQLWLFVCQQIERYDPDRASFIYWLNYLLKKRFIVEAIKTVVGKPDIMIASSDEIEQIPQDEAEPSTSELLRQYIFEDPENRLKQKRLKNYPSFTFQTLLKWRMEGKKWKDISVQTGVKVATLSDFYQRELKQVNSILKDYLNS
>NC_019693.1|WP_052315743.1|3493070_3493976_-|DUF1822-family-protein
MTSIHRNQLTFTTPLTRSWQDIARKFSRQQSNSVKAERVYRNTLAVLAVNFYCKCMGITTDLEESDSWDPVMQTLSDVADLQLKNLGKIECRPLSLGSEIVEIPAEVWGDRIGYVAVQFSESAREATLYGFIKTVEMEEIPLSQFQTLENFLDYIHQLQPKPAIQLTQWLHHIFEAGWDTVEEILGPQKTELAFNVRRASVKRGKVIELTRAGETVALVVGMKPAQAPEMDIWIEVYPTDERVYLPPSLNLIILDAEGVAVMQAQARNTKNIQLNFSGEPGEQFSVRVTLDDVSVTEAFII
>NC_019693.1|WP_015149061.1|3490520_3493037_-|CHASE2-domain-containing-protein
MGKLVVIKLDGDFQRQEVRVMLEIGLEGDRPWIELPGKLPRAPELSTQLYDWVEKYRNIGEPSRRIKTKKIIYDGGIEKRIEECCEAAEVLSDRFNDWLESPEFRHCDRRLREELSREDEIRVLIRTGDRQLQKLPWHLWDFFDRYVKAELALSPPSVQAVTSLKVPKQKVKILAILGHDEGIETTVDRQILENLPQAKVNFLVKPQYREINDSLWEEKWDILFFAGHSESENERGVIYINEREKLSIAELKYGLRKAVNRGLQLAIFNSCDGLGLAQELAELQIPQTIVMREPVPDRVAHEFLKNFLQAFSHGEPFYLAVRQARERLQGLEKEFPCATWLPVICQNPAVKPLNWTDLIVQPTPEPIVPAPQPIGRSPWQTVSTVLFVSVLVTSLVMGMRALGVLEPLELKAFDRLMQLRPSEGLDSRITIVKITDKDLPSPEQNPLTSLPDDKLDRLLKILEPLQPRAIALNLYRDFPVNVNYPELAAKLQQNSSFIALCAVGSHTPDKPSIAPPNEVSETLRLGFGDILPDDDRILRRYILAMSPSNSLCQTDKSFSLQVARHYLQAEGIKLKLTQQEYFQLGRVVFQTLERDSGGYHDLDSRGHQILLNYRAGGKVAEELELSDILQGRIDPDLIRDRIVLIGTTSSQITNLLTPIDYDKDISRLYDANPRRKKTLEMPPVVFQAHAIAQILGAVLDNRPLLGVWPKWGEMLWIWGWSIAGGLVAFYLRSGWHFGTVFGAGLGSLLAISFVFLVKGGWWVPLVPSALGFVTSGGSMAVLLRLGIQGGIAIASLSGLSFLLLMGGTWVPLVPSLLALISSGGIVLFYNRFILNKKY
>NC_019693.1|WP_015149060.1|3489617_3490496_-|DUF928-domain-containing-protein
MSKKIEINNSIQIWVILACLMAALSYWVLPGNGQIPPSFNPLRFIPREVYNEDTSNGSGEGKPGDTEPGGGTRPSNLEGSLCPEEVAKPLKALVPSRIVMEQTESGDRRVEYVEEYTVSSSPTFWFFVPYRAPLQAEFALVNENAEELYSTTITLPENPGIIGIGIPAVATDKLLELGKYYRWQLTIVCYPDRPSLNNLFVQGWVQQVTPSQQISQWQGINRQEMPYETLRQAVAGYATEGIWYDALTLLGDRRLQNPSNSEITGDWQSLLNSVNLGDFADEAIVERYVIEP
>NC_019693.1|WP_044195128.1|3486850_3489562_+|CHAT-domain-containing-protein
MARKRDIFYHSFRFIFKLKFKLMVWAICGLILSLNLPVLSAQIGQGLSGFAENAHPAIAQSIEPESLLERARTAYQNEEFLEAAQLLQQAEAMFGDAVVDRAVSLSYLSLVYQKLGQWPEATEAIATSLSLLENTANVPLSVLAQTLNAQGNLQLAQGQAEAALETWKQAEMAYQKSGDREGVRGSLMNQAKALESMGFSRAACNTVLEVLEVEGLTCESLVQSPDPESTSKKSNLDEFLISLQRQPNSAIKAMALRSLGNLLRSFGYLERSQQILEQSLQVTETLQSPQEISLSLLNLGNTARAQEDFTHALAFYNQAAIAASSPATRLQAYLNQLSLTIEVEQIATASPIITQIQSELDDLPTSAIAVYARINFARSLWELRNQSNRYDLAQIEELLKIAEQQAQELGDDRLRSHALGNRAWLSEQKEDWLQAQQLTTDAIFLAKDAPEIAYQWQWQMARIKQKNQENSSALQFYDAAIASLKLVRKDLTGINPDIQLSFQKQIDPLYREFVDLLLQGENPSTENLEKARQAIADLQLAELENFLRCSLQTETPVELDRLADEHQAAIIYPIILPQRLAVIVKRPGSSDLLYFQTEILRQEVDQKLDNLRKQLERTSISIEAKQLSQEVYDWLIQPIETASNSQINPIKTLVFVLEGRLRNIPMAALSNSNGEYVVQKYAVALNLGLELKDPQPLAQQSLTALLAGITEPLRGMPALEYADRELNLVENSVSSSRQLRNQKFKKETLENQINSRSFAIVHLATHGEFSSQLEKTGIEAWDGRINLDELSTIFTQQTENQPSPIELLVLSACKTAEGDDRAVLGLAGVAVRSGARSTVASLWYIDDETSALLMNRFYYYLNDPRALSKAEALRLAQDDIRKEFINKRAPYYWGSFVLVGNWL
>NC_019693.1|WP_015149058.1|3482582_3486905_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MGHRQRSQISGSSLTGKLAILSIALCLFPPIAVAQIVPDATLPVNSIVTPDGDALIIEGGTSSGFNLFHSFQEFSIPTDTAAFFNNDPTIANIFTRITGISVSNIDGVLATTGTANLFLLNPNGIVFGPNAQLSIGGSFLATTADRFTFADRTQFGADVQTPPQLTISTPIGLQYGSNPGDIAVGGAELQISPGETLTLAGGNVFLEGAALLAESGRIELSSAIAGELSLIPLQQPSETASTVTYGDIQLSQGSAIDTSGEAGGDIQLQGRRIELRDGSLLQTTTLGEAPGGNLTIRAAESLKLSGNDLAGFPSGLLAETAGAGDGGNIGIVARRVVFQDGGQASASALAGSTGNGGNVRVNALEFIEISGSTGAIADPMTGEEFGLKSGLFTEAQGAGNGGNIEINSPRITLRDGAQVSAVTIGAGNGGNIAIAATTVELVGISGILVNADIGSSGDGGDIAIATNQAIVRDGAQIASTTFGEGDAGDIRLNASELLQVSGTTADFFGGIFAEVAQESTGNGGNITLESDRLLVDNGASISTSTTGQGQGGILTIYSQSLTVRGGQIAAATVGEFPGGSISIVSDSVELSGTTPDGFPSGIFTQTLGSGNAGDLTISSSQLTIRDGAKLSVSGEATGNAGSLTVNSDALELQNAAILTGETVSGQGGNIGINADTIILRGNSNISTTAGTQDNPGNGGNITIDTEAIAGLENSNISANAFNGSGGAIAIATDVILGLEAKTREQLESELGEDLTQFDPNTLSTNDITAISRTDPSLSGTIGINTPDVDPSKGFVELPDETVDVARLINDTVCRLGQGSEFVQTGRGGLPPSPTDPLTTNEVWEDWRLPGISEEGQTQENNINRSLPQGDRMIEARDWQMKENGDLALIAPPLASEVAIGEAIATGCVPLQAKMRSPSGDILAIAAFPDKPSSQTVQVQQFEAIGSTVFTPEQLAAVTQPFLQDPLTFDRLLNARSAIAQLYLDAGYLTSGAYIPPQIVQNGVVTIQVVEGQLENIAVRTNGRLNESYIQQRLERIISEPVHPERVLTALQLLQLDENIETISAELSPGVRPGTNLLTVTVKEKPLLGTQLSVDNNRAPSVGSFRQTVQTNFSNLLGLGDVATVAYTHTDGSNTWDVVYGVPVNARNGMLSFYYGRGDSKIVEAPFDELEIEADSQVYEIAYRQPFQSIQKKARENGEDEYVFQEFALGLTASRRNSQTSLLGVDFPLSPGANDAGETRISALRFFQEWTQRQDRQVFAARSQLSLGVGWFDATVNESEPDSRFLAWRGQAQWVRRVTDNTLLLMRGDLQLSPNALLPFEQFGLGGQDRIRGYRQDALLTDNGALASVELRLPIPVVSQRGRLVQIAPFLDAGVGWNSDDRPNPEQNALLSAGVGLRMQFGNRLTARVDWGIPLVNLDSRAKTWQENGIYFTIVSDLFSN
>NC_019693.1|WP_015149057.1|3482152_3482461_+|hypothetical-protein
MEHRELQDISGHQAEAIPIFFVWGRSASFTRSRWWIKADEPVFNRLFEPEERMIEVKAISFEATETNSSVTSVPQPSSHYVGVLVLGILGIGLALKRQRGTM
>NC_019693.1|WP_015149056.1|3481359_3481995_+|PEP-CTERM-sorting-domain-containing-protein
MTYFWNLENREPQDLYGHQIESLSGGFLSIKSTTNSNAEAISLPFIWGRGGSFTRSHRWIDPDENFTNTFGQRPDDVYWWQLRSLASSSNNTNGGINLTSVNHQEVSSEDNIFLVLAQNDILDPFINTANPIRFRSENPLTDETIFNRLFTQDYQVVEVTEISFEETETNSPVTSVPEPSSYVGVLVLGILGVGLALKRQLGTMRSRSSSV
>NC_019693.1|WP_015149055.1|3472580_3481184_+|S8-family-serine-peptidase
MPGINDNEFNLVGGLTDDFLEDKLVSPLPSILAAGSELSLDADRLGEALTPEPFVEGEDEFPQMVLEKGNLLDKEVIVSSTPDNSDSDSLTNYRQDDEVTSLIDIDEDDPLINGGDVSSEGSLSEEPSESDTEESDRLSDNPSESSESDNSDRKTLAEDRDEFLEAEPPTLETDDEAIALDNGGAVSEEESHSEEPSNSNTEEIEGLDNPSESSESDKSDRKTLAEDRDESSEAEPLELETNDEAIALDNSPHLISDEETPASDTNSLKSSLSDVPNEDSGESALSSAVTASSGETDIDVEVEDTKENTEADIKENPESKSLLNSDRETDSDSENNNETSITDATASSDGDDSNLPKNLENFANVTFDSGVFVVGESGKVQFDYLFDGGGYEGKLAAFSLTGMEPFQQQGLEAFIQEALRRSLSQSLEGHVVISDRTEGARFSGELGEANQNRGDYQGIKTLDMTPGDKFGVLLVPQGTLQEVWEQLEAGNFESVSAAKRPLFSMSTANPEDGFNFGQIADVFGDGSTFVFEDLRVDKGTDLDYNDVIFQVRGAIAEAAFLKDVINPNKNWLETGELSKAIENYAKREVDDSTEEETEPQTPIAETLPDSVKYALLRSQDLENYDPKALETTRQWVVGVTPGYSASEFATLYNAEDIGATGHIPDTYIWNFSEFGNAQQVAKRLSDLKGVEFAYPLTRVQLEPLSTPNDPLFNQQWHLENTGQTGGTAGVDANIITVWDEITGEGIKIAIVDDGVQHTHPDLSDRYRPDLSLDLNEGDILHRNYDTDPAPFSHQTIASNFANPQPLIDNDWSWELPTLDVGLKGVIDHAKLKFNFDHPAPNELDIYLYSPKGTDLLLPPITTSGEFEIDTALFNGEEANGEWRLMFEDRVLGNSGTLNNWSLELQASNKHGTSVAGVAVGTSNNNLGISGIAPNAEWGGIRLIADKVTDIQIADALYSNLNQSIQVYNNSWKPPAFWFGEQGQGLMALHQGVTTGRGDLGNIYLFGAGNDGENVENINYNAYANSRYTIAVGAVDSRGRKPLYSQEGAALFVSAPSSGNTGGITTTDLLGDHGWNSEGSGKFGLNYTDLDYTNDFGGTSSATPVVSGVVALMLEANPNLTWRDVQHILAETANRNAIADSSANWSGNDGDRIRHSDRYGFGLVDAASAVAAASTWTSVAPEVAITSGTLTVDRAIPDNTFAGITQEFTLDRNITLESVEVVFDADHPYRGDLWIELTAPDGTKSLLANPSNDDGHDYQNWVFNSVRHWGDSSQGTWQLRVRDRYPSYSGSWNSWKLNFYGTQPTVTLEASDTNASETGDAGEYTFIRTGDITHPLTVSYAIAGSATNTIDYTELTGSITIPAGSDRITLPLSAIDDEEVEGTETVVLTLAAGSAYNVGTQNMGTVEIADNDLPNVPPTLTPQTATQTYTEDIPLDLIDLVVSDPDAGDTLTVELQLDPTAGILTTGTVDGISSVYNSATGLWQVSGDVTTVNAVLADVRFIPTENYYGEVTIATSVTDNIAPAVTGAIALSGTPVNDAPALSQITTLSGATQGLPFTISYEDLLNASDASDVEGDAITFQIAGITSGTFTKNGQSVTVGETELAAGESLIWYPDTMGNAVPAFAVTAFDGVDESQNAVNVAIAVDELPTIIINATDAIASESGDRGQFTILRSGNTDNQLTVNLAASGNAVNGSDYSAIPNSITIPAGQSSIAIDITAIDDSLVEGDEQVILTLSVGSDYQIGGQNSATVTIVDNDNEPLPMVMLAPGNLNASESGVAGNLLVFRNNGLGQELTVNYSLGGTAENGVDYQPLTGSVTIDANSFFATIQIIPIDDSEFEGTETVSVNLVAGAGYQVSPNGYEVQIADNDKPSVSLVATDGEASEDGDLGYMTLTRTGITTNPLTVNYAIGGTATNGMDYTALSGSIEIPAGLSSITIPIQAIDDNSVEGDETVVLTLTDNSAYNVGTDKTATVSIIENDLEPFTPVESILTGVDNGSVAWGDYDGDGDLDLLITGRRGMSRFSKIYQNNGSGNFIDIDAGLIGVDNGSVAWGDYDGDGDLDILLTGDSNGNSNGIAKIYRNDGGNFIDIAANLPGVVNSSVEWGDYDNDGDLDILLTGHHFSSGGYGSGGYGGVDVGTISQIYRNDDGTFIESGISLIGVGSGSAAWGDYDRDGDLDIVLTGITDDGSSIVGVSKIYRNDSGSFTDIGAMLPEISWSSAAWGDYDNDGDLDLVITGFNDTVGEVSQLYQNNEGTFIQVETNLPGITDSAVAWGDYDNDGDLDILLVGQKESSNSVATIYRNDGDNEFTDIDANLKLMPPNVYNTGDRFAVWGDYDRDGNLDILQTGLDSSNNFIAQIYRNNSVIANNSPTSPDGLNALVHENSVTLSWEPGTDSETPQNGLTYNLRVGTTPGASDIVSPMSNSDGTRQLAQMGNVHQNTNWTINNLKPGTYYWSVQAVDSAFAGSEFATEGTFTMTAIGEIQWIQQIGTASFDDSREVAADKWGNVYITGYTLGSLGGTNAGNHDAILTKYDTNGNLLWTRQLGTPEVDVAFGVATDSVGNVYITGQTAGALEGTNAGNDDAFVTKYDTNGDLLWTRQLGTPGVDIAYGVATDHDDNFYITGYTTGSLASPNAGEYDAFIAKYDSNGNQLWSQQLGSLQTDIARGVAIDGGGNVYISGRTTGSLDGNNAGNFDAFFAKYDRDGNLVWIRQLGTSGWDQSPGISTDKNGNIYITGYTTGNLEGVNAGTRDIFVTKYDPSGNLLWTEQLGTSSLDYSYGSATDSAGNVYITGHTTGSLEGENSGGYDVFAIKLDSNGNQVWIQQFGTSAIDYSRGIATDPAGNIYITGSTQGSFGQTTAGNSDVWVAKLS
>NC_019693.1|WP_015149066.1|3497504_3498956_-|IS66-family-transposase
MEESITIGGIKIPRADWERTPESVKNVVRNIEQRIAAIEERLGLNASNSSIPPSKQPPIAKEKKQEKRPRRKRGGQKGHKGFTRHLYEPSECSEIIDHQPETCKHCQAPLTGEDAQPYRHQIVDIPPVAPVVTEHRLHALSCQCCGQTTRAELPNDINPSGYGERLQSLVALLSGAYRLSHNQVQTLMRDLWQVHLSTGTVNRIRQRVSQKLSQVVDEARAYIMKSGTAYVDETSWSQNNGDGNNPENASAWLWTAVSNNVAVYQVTLNRARSSAEALLGKNYTGLVVSDRYSVYNGWTVEQRQVCWAHLKRDFKRMAERSGVSKDIGEALLKQTKRLFHWWHRVRDGTLSTELFQAAMARLRQSVHHLLSEAASLCHSSREQTPLAKTARTCEQILKLEPALWTFVEVNAVEPTNNTAERAFPRAVIWRDLSYGSWSRSGSEFVERLLTVVTSLRFQERPVLEFLMQVLHSESVSLLPLPPE
>NC_019693.1|WP_156823840.1|3499059_3499296_-|hypothetical-protein
MQHLPFELPHPPAVEHPTRSAFVPVLVGLCVWRGGSTLSSNSYRIHSTSDRLVNNCRWRQLSDIAPVLLQGSILSGTH
>NC_019693.1|WP_015149067.1|3499217_3499511_-|HNH-endonuclease
MSNSRYSQDWQAIALAIKEQAGWRCSKCGLQCLRPGDPKNHLSKSERGKLMLNVHHHNRIPEDNRPENLIALCSTCHLSYHTRQQSNIPPGQLSFQF
>NC_019693.1|WP_015149068.1|3499875_3500580_+|hypothetical-protein
MLEKINKSINLFMQNWMLFSMIVLTVWLPASILLVYLRWYVFPEMTGGDELQILAKEYRVQGLIETIFGPFCTGALIYALAQIKQDAMPTYGECMAHAARRSFKLVGTRIGTGLIVVGGFLLLIVPGIILALRYALTDTVVTLDRIDGANARKYSAQLTEGKRGELLGTMIISFSLVLLASVFVSLLFSMFISEAEGGIFVLDVLYECLIQLAITVITTTILFLFYWESKEQES
>NC_019693.1|WP_156823841.1|3500730_3500901_-|hypothetical-protein
MLRVDSIGQSECRSWDAIAYARAALTARRIRSIVQIGFGSGVAIAYKIVLLCGTAD
>NC_019693.1|WP_015149069.1|3501471_3502602_+|IS701-family-transposase
MDSILTPAIALVNVLLNIMPSIYQRDSIQALFGLFLEGNGYPLPQHCKNKSASALSRFLNHYNWSTRAVIKAVRADIVAQIKTLAPTGRRPILYLILDMTTLEKVGQFTGLNNLIRVYNGKRGLHLLVLYILLGERRLPWGFKVYRGKDETPPVQLAIRLLNTLPQSLKTRFEIRILADTAFGSIDFLKWINQHKNYHGIVGIRKDRRLSDGIRVSEVSKRGQQVVLHGIDFPVTLSWYWVKKENGQKEKRFVISTKPLSAVYITMLGRRRWNIEGFFKVAKHRFGLHRFGQGTLKGVYRWIILSMIAYLLAHYACLWSGSTTRTDWGEASKLAKETLFPRLVLRMLLIEIKEKAWIARQQGLDIRITTTRPCLAN
>NC_019693.1|WP_015146995.1|3503106_3504729_-|IS1634-family-transposase
MTDIASDIIVQDIDHCGIVSGIIDEIGLVELINRELEPHPLTLVSPGIVVKAMILNGLGLVSAPLYLFPQFFVGKATEHLLGEGITPEMLNDDRLGRVLDELYKVGITQLFVKVALAAAKKFRVNTRSKHLDSTSFHVHGQYLREPNLTGEPVPIEITYGYSRDHRPDLKQFIVDLICSSDGDIPLYLRVASGNESDSAIFAKLMKEFRENWDMDGLFVADAALYNQENLRQINHLKWVSRVPASLKAAKELLSEPAESDLKKCQLDGYRIKSCEITYEDIKQRWLLVESEKRKESDLKQLKKKIKNLAEKGRAELKKLSQQKFACQPDAEQAVEQFNKKLRYHTITGFEILTVPYYTQPGRPPKGAKPAGYCYQIQGTLSENEAAIEQEKIRAGRFILATNVLDVNELSDEQILEEYKNQQSTERGFRFLKDPMFFTDSVFLKNSERIEALAMVMGLCLLVYSLGQRALREALAQAKKSIKNQVGKPTTTPTLRWVFQCFQSIHLLTVDGVKKITYLTDERRWILQFLGASCQKYYLLT
>NC_019693.1|WP_044195134.1|3504753_3505227_-|hypothetical-protein
MDVYMGVTRPSQPVTPSEVGGDKAQGKSEFNPRKNPVAQIYFPTNDSKLDSQDIGILFLLANALEGAEFVSLNFYGYADKREAVDYNLQLTDLRTASVSSRLLTLLDKQNVNDYEALDVPLSEIERPQNGTTAEELKPFRRVDIEIQQLKSHIPQVK
>NC_019693.1|WP_156824047.1|3505461_3506658_+|ISL3-family-transposase
MSQLLDLAGVWVKDYKIHKEIGLVLQIESLQKLAVCPLCGHQSNKLHQNHWYLVKDLPFSQHPTYLRVNRRQFKCQTCQKPFSESLDYVNPKRNYTKRLTLKIVEEVLESNIQSVARRYQVTEEEIQTMLSDVGSELLQEKPAPFRRLGIDEISQRKGQGNYCAVLVDIDAGKPVGIVDSRRKEELLKVLQGWGSEILNFIEEVSIDLWMPYKTLVEELLPHAQIVADRFHLMKGLNEELDSQRKFEKYLINSQENYPEKSDLISAINKSKYPLVKNEKDLTEKQNKKLKEVKLKFPQLAIMHDLKEEFRDIFESKQQGTEGLVKLVDWLFKAQQSFPTFTKTVIRWFPEIVNYFENRTSNGVVEGINNKLKVIKKSAYGLPKFENFRLRSLLNWMFT
>NC_019693.1|WP_015149072.1|3506669_3507866_-|DUF4157-domain-containing-protein
MVYQKLQKSSAKISPTHRTFQAPRPSSKRKSAEDAPQQDIQRSPSNSNRLGRISVYPATLEAPVLQPKLTIGAANDPYEKEADQVAHQVVTKIHSPAFQDPQPQAKESIQRQTGPRIGIRRKPTTQGEATEATPDLEASIRAARSSGRPIKPSVKEPMEQAFGSDFSQVRIHTDAQSDQLNRSIQAKAFTTGQDIFFRGGEYNPDSIAGQELMAHELTHVVQQTGKIQPTIATEELSRSESIPSLQRKCASCEAEEKKQDKKIQKKAISSSGERVQRSVFDALNNAIDEVFNNSDDNEMPAFPPCENSPQTLPSLDRWLDNSALESIRHNNKVLSQSKSPGGDSQAATSLVKQLLFSWGCDFYNQNFLPKFGVNRTFGAETKTAVKQFQTYFSWLSRT

Crispr_ID: NC_019693_29

• CRISPR_ID: NC_019693_29
• CRISPR_location: 3501238-3501340
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_29

Consensus_repeat	Method
CCGTGCTAGGGAAACCCCTTTCGCCTAAAC	CRISPRCasFinder

spacers of NC_019693_29

>29.1|3501268|43|NC_019693|CRISPRCasFinder
AAGTCTAAGCTGAGTTTTTAATCTAGCCTCGATAAGCTTTTGA

CRISPR arrays and Neighbor proteins around NC_019693_29

CRISPR arrays

The CRISPR arrays of NC_019693_29

>merge|NC_019693|29|3501238-3501340|CRISPRCasFinder
CCGTGCTAGGGAAACCCCTTTCGCCTAAACAAGTCTAAGCTGAGTTTTTAATCTAGCCTCGATAAGCTTTTGACCGTGCTAGGGAAACCACTTTCGCCTAAAC

>NC_019693|29|29|3501238-3501340|CRISPRCasFinder
CCGTGCTAGGGAAACCCCTTTCGCCTAAAC	AAGTCTAAGCTGAGTTTTTAATCTAGCCTCGATAAGCTTTTGA
CCGTGCTAGGGAAACCACTTTCGCCTAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015149067.1|3499217_3499511_-|HNH-endonuclease	unknown	unknown	gnl|CDD|225724
NC_019693.1|WP_015149072.1|3506669_3507866_-|DUF4157-domain-containing-protein	unknown	unknown	gnl|CDD|379338
NC_019693.1|WP_015149066.1|3497504_3498956_-|IS66-family-transposase	unknown	unknown	gnl|CDD|376980
NC_019693.1|WP_015149069.1|3501471_3502602_+|IS701-family-transposase	unknown	unknown	gnl|CDD|376573
NC_019693.1|WP_156823842.1|3508845_3509001_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044195134.1|3504753_3505227_-|hypothetical-protein	unknown	unknown	gnl|CDD|143586
NC_019693.1|WP_156823840.1|3499059_3499296_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149061.1|3490520_3493037_-|CHASE2-domain-containing-protein	unknown	unknown	gnl|CDD|226703
NC_019693.1|WP_052315743.1|3493070_3493976_-|DUF1822-family-protein	unknown	unknown	gnl|CDD|370155
NC_019693.1|WP_015149078.1|3512473_3512995_-|photosystem-I-assembly-protein-Ycf3	unknown	unknown	gnl|CDD|179448
NC_019693.1|WP_015146995.1|3503106_3504729_-|IS1634-family-transposase	unknown	unknown	gnl|CDD|227708
NC_019693.1|WP_156823841.1|3500730_3500901_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149060.1|3489617_3490496_-|DUF928-domain-containing-protein	unknown	unknown	gnl|CDD|368720
NC_019693.1|WP_015149076.1|3509469_3511839_-|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|373105
NC_019693.1|WP_015149077.1|3512075_3512357_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	unknown	unknown	gnl|CDD|178810
NC_019693.1|WP_015149063.1|3494000_3494612_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149064.1|3495186_3495510_+|membrane-protease-regulatory-membrane-protein	unknown	unknown	gnl|CDD|376684
NC_019693.1|WP_015149073.1|3508447_3508654_-|Rho-termination-factor	unknown	unknown	gnl|CDD|162030
NC_019693.1|WP_156824047.1|3505461_3506658_+|ISL3-family-transposase	unknown	unknown	gnl|CDD|376574
NC_019693.1|WP_015149068.1|3499875_3500580_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015149067.1|3499217_3499511_-|HNH-endonuclease	gnl|CDD|225724	COG3183, COG3183, Predicted restriction endonuclease [Defense mechanisms].	0.000405216
NC_019693.1|WP_015149072.1|3506669_3507866_-|DUF4157-domain-containing-protein	gnl|CDD|379338	pfam13699, DUF4157, Domain of unknown function (DUF4157). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 80 amino acids in length. This domain contains an HEXXH motif that is characteristic of many families of metallopeptidases. However, no peptidase activity has been shown for this domain.	9.34046e-38
NC_019693.1|WP_015149066.1|3497504_3498956_-|IS66-family-transposase	gnl|CDD|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	1.75586e-39
NC_019693.1|WP_015149069.1|3501471_3502602_+|IS701-family-transposase	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	9.45503e-08
NC_019693.1|WP_044195134.1|3504753_3505227_-|hypothetical-protein	gnl|CDD|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	6.46554e-07
NC_019693.1|WP_015149061.1|3490520_3493037_-|CHASE2-domain-containing-protein	gnl|CDD|226703	COG4252, COG4252, Predicted transmembrane sensor domain [Signal transduction mechanisms].	1.90146e-102
NC_019693.1|WP_052315743.1|3493070_3493976_-|DUF1822-family-protein	gnl|CDD|370155	pfam08852, DUF1822, Protein of unknown function (DUF1822). This family of proteins are functionally uncharacterized.	1.33023e-63
NC_019693.1|WP_015149078.1|3512473_3512995_-|photosystem-I-assembly-protein-Ycf3	gnl|CDD|179448	PRK02603, PRK02603, photosystem I assembly protein Ycf3; Provisional.	5.00495e-116
NC_019693.1|WP_015146995.1|3503106_3504729_-|IS1634-family-transposase	gnl|CDD|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	2.28857e-66
NC_019693.1|WP_015149060.1|3489617_3490496_-|DUF928-domain-containing-protein	gnl|CDD|368720	pfam06051, DUF928, Domain of Unknown Function (DUF928). Family of uncharacterized bacterial protein.	6.69248e-66
NC_019693.1|WP_015149076.1|3509469_3511839_-|CHAT-domain-containing-protein	gnl|CDD|373105	pfam14516, AAA_35, AAA-like domain. This family of proteins are part of the AAA superfamily.	0
NC_019693.1|WP_015149077.1|3512075_3512357_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	gnl|CDD|178810	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC.	1.20138e-32
NC_019693.1|WP_015149064.1|3495186_3495510_+|membrane-protease-regulatory-membrane-protein	gnl|CDD|376684	pfam01957, NfeD, NfeD-like C-terminal, partner-binding. NfeD-like proteins are widely distributed throughout prokaryotes and are frequently associated with genes encoding stomatin-like proteins (slipins). There appear to be three major groups: an ancestral group with only an N-terminal serine protease domain and this C-terminal beta sheet-rich domain which is structurally very similar to the OB-fold domain, associated with its neighboring slipin cluster; a second major group with an additional middle, membrane-spanning domain, associated in some species with eoslipin and in others with yqfA; a final 'artificial' group which unites truncated forms lacking the protease region and associated with their ancestral gene partner, either yqfA or eoslipin. This NefD, C-terminal, domain appears to be the major one for relating to the associated protein. NfeD homologs are clearly reliant on their conserved gene neighbor which is assumed to be necessary for function, either through direct physical interaction or by functioning in the same pathway, possibly involve with lipid-rafts.	1.22281e-10
NC_019693.1|WP_156824047.1|3505461_3506658_+|ISL3-family-transposase	gnl|CDD|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	4.81102e-70
NC_019693.1|WP_015149073.1|3508447_3508654_-|Rho-termination-factor	gnl|CDD|162030	TIGR00767, Transcription_termination_factor_Rho, transcription termination factor Rho. This RNA helicase, the transcription termination factor Rho, occurs in nearly all bacteria but is missing from the Cyanobacteria, the Mollicutes (Mycoplasmas), and various Lactobacillales including Streptococcus. It is also missing, of course, from the Archaea, which also lack Nus factors. Members of this family from Micrococcus luteus, Mycobacterium tuberculosis, and related species have a related but highly variable long, highly charged insert near the amino end. Members of this family differ in the specificity of RNA binding. [Transcription, Transcription factors].	0.00156931

Protein sequences

>NC_019693.1|WP_156823841.1|3500730_3500901_-|hypothetical-protein
MLRVDSIGQSECRSWDAIAYARAALTARRIRSIVQIGFGSGVAIAYKIVLLCGTAD
>NC_019693.1|WP_015149068.1|3499875_3500580_+|hypothetical-protein
MLEKINKSINLFMQNWMLFSMIVLTVWLPASILLVYLRWYVFPEMTGGDELQILAKEYRVQGLIETIFGPFCTGALIYALAQIKQDAMPTYGECMAHAARRSFKLVGTRIGTGLIVVGGFLLLIVPGIILALRYALTDTVVTLDRIDGANARKYSAQLTEGKRGELLGTMIISFSLVLLASVFVSLLFSMFISEAEGGIFVLDVLYECLIQLAITVITTTILFLFYWESKEQES
>NC_019693.1|WP_015149067.1|3499217_3499511_-|HNH-endonuclease
MSNSRYSQDWQAIALAIKEQAGWRCSKCGLQCLRPGDPKNHLSKSERGKLMLNVHHHNRIPEDNRPENLIALCSTCHLSYHTRQQSNIPPGQLSFQF
>NC_019693.1|WP_156823840.1|3499059_3499296_-|hypothetical-protein
MQHLPFELPHPPAVEHPTRSAFVPVLVGLCVWRGGSTLSSNSYRIHSTSDRLVNNCRWRQLSDIAPVLLQGSILSGTH
>NC_019693.1|WP_015149066.1|3497504_3498956_-|IS66-family-transposase
MEESITIGGIKIPRADWERTPESVKNVVRNIEQRIAAIEERLGLNASNSSIPPSKQPPIAKEKKQEKRPRRKRGGQKGHKGFTRHLYEPSECSEIIDHQPETCKHCQAPLTGEDAQPYRHQIVDIPPVAPVVTEHRLHALSCQCCGQTTRAELPNDINPSGYGERLQSLVALLSGAYRLSHNQVQTLMRDLWQVHLSTGTVNRIRQRVSQKLSQVVDEARAYIMKSGTAYVDETSWSQNNGDGNNPENASAWLWTAVSNNVAVYQVTLNRARSSAEALLGKNYTGLVVSDRYSVYNGWTVEQRQVCWAHLKRDFKRMAERSGVSKDIGEALLKQTKRLFHWWHRVRDGTLSTELFQAAMARLRQSVHHLLSEAASLCHSSREQTPLAKTARTCEQILKLEPALWTFVEVNAVEPTNNTAERAFPRAVIWRDLSYGSWSRSGSEFVERLLTVVTSLRFQERPVLEFLMQVLHSESVSLLPLPPE
>NC_019693.1|WP_015149064.1|3495186_3495510_+|membrane-protease-regulatory-membrane-protein
MSSASVHRKNWFVAIVRLLFFKNHSETGHHYVTPNPEFLTSVEQEAIVDEAILPRKVGRVYFGGSWWPARCDRAITLSPGETVYVVGRHNITLLVEPESFIKPTFRR
>NC_019693.1|WP_015149063.1|3494000_3494612_-|hypothetical-protein
MDEAIQNLAMEAKRHPPQSKERQLALTKLIEAISYSGKLCRPRQGQFSHVYEDIYAEALSQLWLFVCQQIERYDPDRASFIYWLNYLLKKRFIVEAIKTVVGKPDIMIASSDEIEQIPQDEAEPSTSELLRQYIFEDPENRLKQKRLKNYPSFTFQTLLKWRMEGKKWKDISVQTGVKVATLSDFYQRELKQVNSILKDYLNS
>NC_019693.1|WP_052315743.1|3493070_3493976_-|DUF1822-family-protein
MTSIHRNQLTFTTPLTRSWQDIARKFSRQQSNSVKAERVYRNTLAVLAVNFYCKCMGITTDLEESDSWDPVMQTLSDVADLQLKNLGKIECRPLSLGSEIVEIPAEVWGDRIGYVAVQFSESAREATLYGFIKTVEMEEIPLSQFQTLENFLDYIHQLQPKPAIQLTQWLHHIFEAGWDTVEEILGPQKTELAFNVRRASVKRGKVIELTRAGETVALVVGMKPAQAPEMDIWIEVYPTDERVYLPPSLNLIILDAEGVAVMQAQARNTKNIQLNFSGEPGEQFSVRVTLDDVSVTEAFII
>NC_019693.1|WP_015149061.1|3490520_3493037_-|CHASE2-domain-containing-protein
MGKLVVIKLDGDFQRQEVRVMLEIGLEGDRPWIELPGKLPRAPELSTQLYDWVEKYRNIGEPSRRIKTKKIIYDGGIEKRIEECCEAAEVLSDRFNDWLESPEFRHCDRRLREELSREDEIRVLIRTGDRQLQKLPWHLWDFFDRYVKAELALSPPSVQAVTSLKVPKQKVKILAILGHDEGIETTVDRQILENLPQAKVNFLVKPQYREINDSLWEEKWDILFFAGHSESENERGVIYINEREKLSIAELKYGLRKAVNRGLQLAIFNSCDGLGLAQELAELQIPQTIVMREPVPDRVAHEFLKNFLQAFSHGEPFYLAVRQARERLQGLEKEFPCATWLPVICQNPAVKPLNWTDLIVQPTPEPIVPAPQPIGRSPWQTVSTVLFVSVLVTSLVMGMRALGVLEPLELKAFDRLMQLRPSEGLDSRITIVKITDKDLPSPEQNPLTSLPDDKLDRLLKILEPLQPRAIALNLYRDFPVNVNYPELAAKLQQNSSFIALCAVGSHTPDKPSIAPPNEVSETLRLGFGDILPDDDRILRRYILAMSPSNSLCQTDKSFSLQVARHYLQAEGIKLKLTQQEYFQLGRVVFQTLERDSGGYHDLDSRGHQILLNYRAGGKVAEELELSDILQGRIDPDLIRDRIVLIGTTSSQITNLLTPIDYDKDISRLYDANPRRKKTLEMPPVVFQAHAIAQILGAVLDNRPLLGVWPKWGEMLWIWGWSIAGGLVAFYLRSGWHFGTVFGAGLGSLLAISFVFLVKGGWWVPLVPSALGFVTSGGSMAVLLRLGIQGGIAIASLSGLSFLLLMGGTWVPLVPSLLALISSGGIVLFYNRFILNKKY
>NC_019693.1|WP_015149060.1|3489617_3490496_-|DUF928-domain-containing-protein
MSKKIEINNSIQIWVILACLMAALSYWVLPGNGQIPPSFNPLRFIPREVYNEDTSNGSGEGKPGDTEPGGGTRPSNLEGSLCPEEVAKPLKALVPSRIVMEQTESGDRRVEYVEEYTVSSSPTFWFFVPYRAPLQAEFALVNENAEELYSTTITLPENPGIIGIGIPAVATDKLLELGKYYRWQLTIVCYPDRPSLNNLFVQGWVQQVTPSQQISQWQGINRQEMPYETLRQAVAGYATEGIWYDALTLLGDRRLQNPSNSEITGDWQSLLNSVNLGDFADEAIVERYVIEP
>NC_019693.1|WP_015149069.1|3501471_3502602_+|IS701-family-transposase
MDSILTPAIALVNVLLNIMPSIYQRDSIQALFGLFLEGNGYPLPQHCKNKSASALSRFLNHYNWSTRAVIKAVRADIVAQIKTLAPTGRRPILYLILDMTTLEKVGQFTGLNNLIRVYNGKRGLHLLVLYILLGERRLPWGFKVYRGKDETPPVQLAIRLLNTLPQSLKTRFEIRILADTAFGSIDFLKWINQHKNYHGIVGIRKDRRLSDGIRVSEVSKRGQQVVLHGIDFPVTLSWYWVKKENGQKEKRFVISTKPLSAVYITMLGRRRWNIEGFFKVAKHRFGLHRFGQGTLKGVYRWIILSMIAYLLAHYACLWSGSTTRTDWGEASKLAKETLFPRLVLRMLLIEIKEKAWIARQQGLDIRITTTRPCLAN
>NC_019693.1|WP_015146995.1|3503106_3504729_-|IS1634-family-transposase
MTDIASDIIVQDIDHCGIVSGIIDEIGLVELINRELEPHPLTLVSPGIVVKAMILNGLGLVSAPLYLFPQFFVGKATEHLLGEGITPEMLNDDRLGRVLDELYKVGITQLFVKVALAAAKKFRVNTRSKHLDSTSFHVHGQYLREPNLTGEPVPIEITYGYSRDHRPDLKQFIVDLICSSDGDIPLYLRVASGNESDSAIFAKLMKEFRENWDMDGLFVADAALYNQENLRQINHLKWVSRVPASLKAAKELLSEPAESDLKKCQLDGYRIKSCEITYEDIKQRWLLVESEKRKESDLKQLKKKIKNLAEKGRAELKKLSQQKFACQPDAEQAVEQFNKKLRYHTITGFEILTVPYYTQPGRPPKGAKPAGYCYQIQGTLSENEAAIEQEKIRAGRFILATNVLDVNELSDEQILEEYKNQQSTERGFRFLKDPMFFTDSVFLKNSERIEALAMVMGLCLLVYSLGQRALREALAQAKKSIKNQVGKPTTTPTLRWVFQCFQSIHLLTVDGVKKITYLTDERRWILQFLGASCQKYYLLT
>NC_019693.1|WP_044195134.1|3504753_3505227_-|hypothetical-protein
MDVYMGVTRPSQPVTPSEVGGDKAQGKSEFNPRKNPVAQIYFPTNDSKLDSQDIGILFLLANALEGAEFVSLNFYGYADKREAVDYNLQLTDLRTASVSSRLLTLLDKQNVNDYEALDVPLSEIERPQNGTTAEELKPFRRVDIEIQQLKSHIPQVK
>NC_019693.1|WP_156824047.1|3505461_3506658_+|ISL3-family-transposase
MSQLLDLAGVWVKDYKIHKEIGLVLQIESLQKLAVCPLCGHQSNKLHQNHWYLVKDLPFSQHPTYLRVNRRQFKCQTCQKPFSESLDYVNPKRNYTKRLTLKIVEEVLESNIQSVARRYQVTEEEIQTMLSDVGSELLQEKPAPFRRLGIDEISQRKGQGNYCAVLVDIDAGKPVGIVDSRRKEELLKVLQGWGSEILNFIEEVSIDLWMPYKTLVEELLPHAQIVADRFHLMKGLNEELDSQRKFEKYLINSQENYPEKSDLISAINKSKYPLVKNEKDLTEKQNKKLKEVKLKFPQLAIMHDLKEEFRDIFESKQQGTEGLVKLVDWLFKAQQSFPTFTKTVIRWFPEIVNYFENRTSNGVVEGINNKLKVIKKSAYGLPKFENFRLRSLLNWMFT
>NC_019693.1|WP_015149072.1|3506669_3507866_-|DUF4157-domain-containing-protein
MVYQKLQKSSAKISPTHRTFQAPRPSSKRKSAEDAPQQDIQRSPSNSNRLGRISVYPATLEAPVLQPKLTIGAANDPYEKEADQVAHQVVTKIHSPAFQDPQPQAKESIQRQTGPRIGIRRKPTTQGEATEATPDLEASIRAARSSGRPIKPSVKEPMEQAFGSDFSQVRIHTDAQSDQLNRSIQAKAFTTGQDIFFRGGEYNPDSIAGQELMAHELTHVVQQTGKIQPTIATEELSRSESIPSLQRKCASCEAEEKKQDKKIQKKAISSSGERVQRSVFDALNNAIDEVFNNSDDNEMPAFPPCENSPQTLPSLDRWLDNSALESIRHNNKVLSQSKSPGGDSQAATSLVKQLLFSWGCDFYNQNFLPKFGVNRTFGAETKTAVKQFQTYFSWLSRT
>NC_019693.1|WP_015149073.1|3508447_3508654_-|Rho-termination-factor
MVKKEDTSDPRDYDILYRLDLEQLRSFAAQYKVKDCQTMSKSEIVEAIKELSRINDEQHRKSKRSRRK
>NC_019693.1|WP_156823842.1|3508845_3509001_+|hypothetical-protein
MARYFQEKMKLSYLQMTGWNDIFNLGSRKVSLHWGQTWIVLTPQKQIVLFF
>NC_019693.1|WP_015149076.1|3509469_3511839_-|CHAT-domain-containing-protein
MAKKILILAANPKNTEILRLEEEVQKIEAGLQRSHRRQAFEIVFRSTEAKPEDLRRAFLDCEPQIVHFSGHGSGTPGLAFLDESGEARLVTAHALANFFKLFQDKIECVILNACYSVVQAEAIGQHIDYVIGMNQAIGDRAAIEFAVGFYDALGAGRSIEDAYLFGCSAIELEGIPEHLTPVLKKKTPGELPGEREQRGSANQVEKSPLEALVTPSRLLDSNRVPLEAIALEEPEGQVSLDSPLYIERPPIESDCYETLIKPGSLIRIKAPHHMGKTSLMSRVLHYGIQQGYRTACLNFQSADSDCFHSLDTFLQWFCASVSEELGLEERIESYWRGILGSKNKCSKYFQTYILAEIDGPIALGLDEVDLIFQYPEVATDFFGLLRAWHEKGKNEPIWKKLRLAIAHSKEVYIPLNINQSPFNVGLPIELPEFTAAQVQELMVRHRLNGSKTNVEQLMNRLGGHPALIRIALYYIAKGRLTLPTLLEVAATEEGPYYAHLRRHLLKVEQDTDLTAAIQQLIAAKGPVEIQSAQAFKLRSMGLVKFQGNAVTFLGDIYRDYFRSRLSPQTTLEEVSPSRSADSITELAARTELAVIVFTDIVSSTGFMASNQELMLQLIDRDFQLMRELSEQFDGKILKYLGDGIMIYFESAVKAVIWAKTLQETLAKNAKNLSNRYILWHRIGIHLGDLIFKDNDVWGTAVNIASRLQSKSKPGGVCISQTVYDVVKRHLSLTVECVENQELRGVCISQTVYDVVKRHLSLTVECVENQELKGIPEPITLYHIKIDLES
>NC_019693.1|WP_015149077.1|3512075_3512357_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC
MIDREQIRKVAHLARLELTDAEEEQFTTQVGSILEYFEQLSELDTENIKPTTRAIDVSNVTRPDELQPFTDLQSIMDAAPDVEGDFFKVPKIL
>NC_019693.1|WP_015149078.1|3512473_3512995_-|photosystem-I-assembly-protein-Ycf3
MPRTQRNDNFIDKTFTVVADIILKILPTNQQSKEAFAYYRDGMSAQADGEYAEALENYTEALSLEEDPYDRSYILYNIGLIHTSNGDRDKALEFYHQALELNPRMPQALNNIAVIFHYQGDQAKDAGETEDAEELYDRAADYWKQAIRQAPNNYIEAQNWLKTTGRSTMDVFF

Crispr_ID: NC_019693_30

• CRISPR_ID: NC_019693_30
• CRISPR_location: 3608024-3608137
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_30

Consensus_repeat	Method
TCATAAATTGTGGAAAGAAACCCGGTTTCT	CRISPRCasFinder

spacers of NC_019693_30

>30.1|3608054|54|NC_019693|CRISPRCasFinder
AAACTTTGCCAGGGGACCAGAAACCGGGTTTCTTGCCTAAGTTTTTGCTACTTG

CRISPR arrays and Neighbor proteins around NC_019693_30

CRISPR arrays

The CRISPR arrays of NC_019693_30

>merge|NC_019693|30|3608024-3608137|CRISPRCasFinder
TCATAAATTGTGGAAAGAAACCCGGTTTCTAAACTTTGCCAGGGGACCAGAAACCGGGTTTCTTGCCTAAGTTTTTGCTACTTGTCATAAATTGTGGAAAGAAACCCGGTTTCT

>NC_019693|30|30|3608024-3608137|CRISPRCasFinder
TCATAAATTGTGGAAAGAAACCCGGTTTCT	AAACTTTGCCAGGGGACCAGAAACCGGGTTTCTTGCCTAAGTTTTTGCTACTTG
TCATAAATTGTGGAAAGAAACCCGGTTTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015149160.1|3608794_3612280_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|378942
NC_019693.1|WP_015149152.1|3597769_3597994_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149168.1|3622287_3622659_-|thiol-reductase-thioredoxin	unknown	unknown	gnl|CDD|200072
NC_019693.1|WP_015149156.1|3602465_3603203_-|WecB/TagA/CpsF-family-glycosyltransferase	unknown	unknown	gnl|CDD|224833
NC_019693.1|WP_015149153.1|3598659_3599622_+|cysteine-synthase-A	unknown	unknown	gnl|CDD|273465
NC_019693.1|WP_015149150.1|3596181_3596700_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149155.1|3600401_3602300_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224048
NC_019693.1|WP_015149167.1|3622129_3622288_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149157.1|3603450_3606801_+|glycosyl-hydrolase-family-15	unknown	unknown	gnl|CDD|366266
NC_019693.1|WP_015149158.1|3607129_3607825_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NC_019693.1|WP_015149169.1|3623682_3624078_+|hypothetical-protein	unknown	unknown	gnl|CDD|372980
NC_019693.1|WP_015149149.1|3594832_3596038_+|phosphoglycerate-kinase	unknown	unknown	gnl|CDD|234613
NC_019693.1|WP_015149161.1|3612923_3613376_+|IS200/IS605-family-transposase	unknown	unknown	gnl|CDD|376616
NC_019693.1|WP_015149163.1|3615790_3617251_-|DASH-family-cryptochrome	unknown	unknown	gnl|CDD|274288
NC_019693.1|WP_015149164.1|3617559_3619143_-|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl|CDD|235050
NC_019693.1|WP_015149154.1|3599905_3600127_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149159.1|3608146_3608647_-|hypothetical-protein	unknown	unknown	gnl|CDD|372967
NC_019693.1|WP_015149165.1|3619743_3621813_-|NAD(P)H-quinone-oxidoreductase-subunit-5	unknown	unknown	gnl|CDD|236005
NC_019693.1|WP_015149162.1|3614056_3615538_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_019693.1|WP_015149151.1|3596696_3597713_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379114

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015149169.1|3623682_3624078_+|hypothetical-protein	gnl|CDD|372980	pfam14250, AbrB-like, AbrB-like transcriptional regulator. This family of DNA-binding proteins is likely to act as a transcriptional regulator. This family does not include E.coli AbrB, which belongs to pfam05145.	3.64625e-41
NC_019693.1|WP_015149168.1|3622287_3622659_-|thiol-reductase-thioredoxin	gnl|CDD|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	4.82289e-28
NC_019693.1|WP_015149156.1|3602465_3603203_-|WecB/TagA/CpsF-family-glycosyltransferase	gnl|CDD|224833	COG1922, WecG, Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane].	4.52506e-80
NC_019693.1|WP_015149153.1|3598659_3599622_+|cysteine-synthase-A	gnl|CDD|273465	TIGR01139, Cysteine_synthase, cysteine synthase A. This model distinguishes cysteine synthase A (CysK) from cysteine synthase B (CysM). CysM differs in having a broader specificity that also allows the use of thiosulfate to produce cysteine thiosulfonate. [Amino acid biosynthesis, Serine family].	1.54166e-171
NC_019693.1|WP_015149155.1|3600401_3602300_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0
NC_019693.1|WP_015149157.1|3603450_3606801_+|glycosyl-hydrolase-family-15	gnl|CDD|366266	pfam00723, Glyco_hydro_15, Glycosyl hydrolases family 15. In higher organisms this family is represented by phosphorylase kinase subunits.	4.33381e-77
NC_019693.1|WP_015149158.1|3607129_3607825_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	3.17567e-28
NC_019693.1|WP_015149149.1|3594832_3596038_+|phosphoglycerate-kinase	gnl|CDD|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NC_019693.1|WP_015149161.1|3612923_3613376_+|IS200/IS605-family-transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	6.5292e-35
NC_019693.1|WP_015149163.1|3615790_3617251_-|DASH-family-cryptochrome	gnl|CDD|274288	TIGR02765, deoxyribodipyrimidine_photolyase, cryptochrome, DASH family. Photolyases and cryptochromes are related flavoproteins. Photolyases harness the energy of blue light to repair DNA damage by removing pyrimidine dimers. Cryptochromes do not repair DNA and are presumed to act instead in some other (possibly unknown) process such as entraining circadian rhythms. This model describes the cryptochrome DASH subfamily, one of at least five major subfamilies, which is found in plants, animals, marine bacteria, etc. Members of this family bind both folate and FAD. They may show weak photolyase activity in vitro but have not been shown to affect DNA repair in vivo. Rather, DASH family cryptochromes have been shown to bind RNA (Vibrio cholerae VC1814), or DNA, and seem likely to act in light-responsive regulatory processes. [Cellular processes, Adaptations to atypical conditions].	0
NC_019693.1|WP_015149164.1|3617559_3619143_-|NADH-quinone-oxidoreductase-subunit-M	gnl|CDD|235050	PRK02546, PRK02546, NAD(P)H-quinone oxidoreductase subunit 4; Provisional.	0
NC_019693.1|WP_015149160.1|3608794_3612280_-|tetratricopeptide-repeat-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	1.44438e-67
NC_019693.1|WP_015149159.1|3608146_3608647_-|hypothetical-protein	gnl|CDD|372967	pfam14218, COP23, Circadian oscillating protein COP23. This family includes the circadian oscillating protein COP23 from Cyanothece sp. (strain PCC 8801). The levels of this peripheral membrane protein display a circadian oscillation.	1.01226e-44
NC_019693.1|WP_015149165.1|3619743_3621813_-|NAD(P)H-quinone-oxidoreductase-subunit-5	gnl|CDD|236005	PRK07376, PRK07376, NADH-quinone oxidoreductase subunit L.	0
NC_019693.1|WP_015149162.1|3614056_3615538_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.39562e-61
NC_019693.1|WP_015149151.1|3596696_3597713_-|AAA-family-ATPase	gnl|CDD|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	5.06391e-15

Protein sequences

>NC_019693.1|WP_015149158.1|3607129_3607825_-|Uma2-family-endonuclease
MTTISVLNTPPLESGDRLTRDEFEHRYHAAPEITKAELVEGVVFVASPVRANRHGRPHALIMAWLSAYWTGTPGVWCYDNATVRLDEENEPQPDALLRLEPAVGGNSSITEDDYIEGAPELIVEIAASSASYDLNDKLNAYQRNGVQEYIVWQIYENKLDWFILEEGRYVALVPDEQGILRSQVFPGLWLSVEALRQRNVVQVVAVVQQGLQTAEHQEFVQRLAQQKPAGD
>NC_019693.1|WP_015149157.1|3603450_3606801_+|glycosyl-hydrolase-family-15
MTLTSSERQTRLDYYYHQIQSLILVRQNPITGLLPASTAINAHGDYTDAWVRDNVYSILAVWGLALAYRKMDDSQGRTYELEHSVVKLMRGLLFCMMRQADKVERFKETQSLLDCLHAKFDTHTGDTVVGDNEWGHLQIDATSIFLLMLAQMSVSGLSIIYTVDEVNFIQNLVYYIGRAYRTPDYGIWERGNKINKGNPELNASSIGMALAALEAINGVNLFGVKGSQSSVIHVLADEIARARQTLESILPRESSSKEVDAALLSIITFPAFAIEDGPLCDRTKQKVITKLQGKYGCKRFLRDGHQTVLEDPWRLHYEPWELKKFENIECEWPLFFTYLFLDGIFRGDRSQTEEYRERLNSLVVESYGLKLLPELYYIPADKVEAERTNPQTQPRLPNENLPLVWAQSLYFLGLMLDEGLLHRGDIDPLGRRRTLAGRRKPVVQIALLAEDEDLQTELAYHGIATQTPAEVEPLQVRKARDLSGVYRQIGRNDKFGLTGRPVRRLRSLTTSNIFRIRGETIVFLPSFLDQQEFYLTLDYHFLVSNIKGELAYIHRHWWRYPQIGGHGVGRPTVTLLLTHAMLETDGSSEGFLPALLELMKELRDGDCEGTPVKLGRLNQLMLTGSIERIDFLHEFQFSENPVQNAAPACYFLAYDAEKNWPLSHTQEFMLECETDPGLLLDSLRSSFNLYEQIELLHTLSRLRGLEFETGLAGPGRPVTVADLLNEVYFKAGTGKAIGDCAIAGSPKRKTTRTEANSTENAAEKQIHWSVVRRAAGLLNKVDIGLSDAVTDILVRQKQITVGKAYTEASLISRPMSYTEIVDKIRQFCGEDIRDRVLTQEILLYLGLLIKAEPDLFNGLLTLRVSYLILLITSELAKELNLTQDEAYERVMELSPFEINNRLREVLKGYAGMNKLLKKQESLHVQQQEQEIEWVVLPSPNETEEISGNWQRRRQLDGAAGRVPKEFYPRVWQVMQHCKGLVIGDKLERRNRLDSELILAEMTPGEKNFALRVEHLLNKIQAPEYRQVNIETLMELAAICDRNPDLQIQEYIVLDVLIGHAVRLAWIESHPERSDFYDEDKALAWPSFYNTSPYVCASFVVKAFRYLTKFGKAIAVG
>NC_019693.1|WP_015149156.1|3602465_3603203_-|WecB/TagA/CpsF-family-glycosyltransferase
MLQVLQKFSVLGLPVHITTHYRDWLQSRLQQRQGTHVVTLNAEMAMQALENLDLAEVIHQADLVIPDGAGVVFYFLVRGRKIQRCPGIELAESLVQLAGDLGEDCSTFFFGGKPGIAEIAAKRWQTELPALAIAGTQDGYLSPEDEPAFKARLQQLQPRLILVGLGVPRQEFWIRENRHLCPDAIWVGVGGSFDIWSGQKERAPVWLQRLQMEWAYRLYQEPWRWRRMLALPHFAWISMKTALRQ
>NC_019693.1|WP_015149155.1|3600401_3602300_+|ABC-transporter-ATP-binding-protein
MTDTVLDVRNLQVQFFTEGRPVKAVDQISFTVQRGQTVGIVGESGSGKSVTSLAVMGLVPTPGRISGGEIWFRGTQEEDPIDLLALPPQAKQQYRGGKISMIFQEPMSSLNPVYNIGFQLTEAILLHHQISESEARRRAIAALQEVKLLPSDAELREQVQLPETATEREIMQQVNQQKLAILKRYPHELSGGQIQRVMIAMAISCDPTLLIADEPTTALDVTVQARILELMRDLRDRRGMSMMFITHDLGVIAEIADQVAVMYQGKIVEQGSVLQIFSNPQHPYTKGLLACRPRPDRRLIYLPTVSDFMEVVTNANGDREIREKHSETHDSLDGVTNIQEVSETDVKQRLTDLQQKSPLLEVRNLEVAFPVRGVFGETQRYIMAVNGVSFEVYPGETLGLVGESGCGKTTLARTLLRLIEPTAGKVLFEGQDVGKLEGRALRQVRREMQIVFQNPFSSLNPRMSIGNLVMEPLKIHGVGESARHRRERSAYLLERVGLNAELMNRYPHEFSGGQRQRICIARALALNPKFIICDESVSALDVSVQAQVLNLLKELQEEFKLTYIFISHDLSVVKFMSDRILVMNKGKIEEVGPAESIYSDPQQDYTRSLISSIPTGTLDRIQEQQAQRQVSA
>NC_019693.1|WP_015149154.1|3599905_3600127_+|hypothetical-protein
MEIKGPKKCWNIELFDDLDIFGGQEISLSIEPGREFWQRLQSFRQELDSEGIWIDPDVFEGVRDSSSGREVIL
>NC_019693.1|WP_015149153.1|3598659_3599622_+|cysteine-synthase-A
MKIARNITELVGRTPLVDLNRIPQAEGCVARIVVKLEGMNPASSVKDRIGVNMINVAEEQGRIIPGKTVLVEPTSGNTGIALAMAAAAKGYQLILTMPETMSQERRLMLSAYGAKVELTPGNMGMKGAISRAQEIVDSTPDAYMLQQFSNPANPQIHQQTTAEEIWEDTDGAVDFLVAGVGTGGTLTGVAEVLKARKPSFKAIAVEPTNSPILSGGSAGPHKIQGIGAGFIPDVLNVELIDEVIVVSDDESMAYGRRLAREEGLLSGISSGAALCAAIRLAQRPENQGKLIVMIQPSFGERYLSTPLFQDPELQEAAAIS
>NC_019693.1|WP_015149152.1|3597769_3597994_-|hypothetical-protein
MKINRPSDKQLLHQALEILSTHLDPSSFARFVALCQLGEGNYLKTKEQLFKRETVNSLYKKIQAFETAKHESKP
>NC_019693.1|WP_015149151.1|3596696_3597713_-|AAA-family-ATPase
MINSFQLNNFGPIRQLTCPHASQINLIIGGNGTGKTILLKALYTAMRTLEDYKRGNEPRSALEILSEKLYWTFEVDQLGDLVQKGADAPLSFQLTFNGQPFLYELGKDTTRTIHHLENQVQPRESNSIFLPPKEIISLQSLILQSREQSKIFGFDDTYLDLARALRQFPKISPNDAEFAHPRQSLEDIFNGKIKYDSKLGNWQFKTGNHLFPMGVTAEGFKKLSILDTLLENGYLDSGSIVFIDEPEAALHPTAISKFLDILAMLAKIGIQFFMASHSYFVIKKLFLISQKNPNLSISILSADEETWNTANLQEGLPDNPIIDESIRLYQEEVRLALE
>NC_019693.1|WP_015149150.1|3596181_3596700_-|hypothetical-protein
MTLDPIIESGMTFGPYPEGHCFYIENSQTYQAIQSDMKMAEFLLLRDPNRSLIWIVEAKSSSPRPETQPNFDEFIQEICDKLTNALTLCIATCLKRHASTYDELPVFFQSLALEKTDFRLILVIQGHQDSWLPPLQDALKKALKPTVKIWKLSPTSVVVMNDKMARDIGLIQ
>NC_019693.1|WP_015149149.1|3594832_3596038_+|phosphoglycerate-kinase
MPKKTVANLSASDLSGKRVLVRADFNVPLDDAGNITDDTRIRAALPTIQDLTGKGAKVILSSHFGRPKGQVNEKMRLTPVAKRLSELLGKEVLKCDDCIGDEVASKVQSMENGQVALLENVRFYAEEEKNDPEFAKKLASVADLYVNDAFGTAHRAHASTEGVTHYLSPSVAGSLMEKELQYLKGAIEEPQRPLAAIIGGSKVSSKIGVIETLLEKCDKLLLGGGMIFTFLKARGISVGNSLVEDDKLELAKSLEAKAKERGVAMLLPTDVVIADKFGADANTQIVSVENIPDGWMGLDIGPDSVKTFQDALADCKTVIWNGPMGVFEIDKFAKGTEAIAHTLSELTPKGTTTIIGGGDSVAAVEKVGLADKMSHISTGGGASLELLEGKELPGVAALDEA
>NC_019693.1|WP_015149159.1|3608146_3608647_-|hypothetical-protein
MSKQKNGVVFSILVILQGVLSACQPVESLPRGTDYSCDLTQNPPVTIARTSVKGDMPVIAWKSTFFEGSGYTPEKRCLEVSERLQTYYQMGLLHYLTTGVQDNQNIICVTRTHGGDCSGLLLTLEPGDNPEQVLKDLVNNQGRMIERSEGTGGKLYIELIPELQSP
>NC_019693.1|WP_015149160.1|3608794_3612280_-|tetratricopeptide-repeat-protein
MSRFLPPLPSKRTGQKSPVLLSVVLLSVALSLVSSPQVSELRLSASPTPGETSEAEEAEADRLLIQGSQQYNRSDLRGAIQSWKTALAIYQQLENRPGISDSLNNLGAAYTNLGQYREAINFYQQSLAIKRQLEDKRGIVASLNNLGLAYDSLGQYREAINFHQQSLEIKRQIEDKGGIANSLNNLGNAYNSLGQYREAINFHQQSLEIKRQIEDKGGIANSLNNLGAAYTNLGQYREAINFHQQSLEIKRQIEDKGGIANSLDNLGVAYNSLGQYREAINFYQQSLEIRRQIEDKGGIAGSLNNLGESYRYLGQYREAINFYQQSLEIQRQIEDKGGIANSLNNLGIVYNSLGQYREAINFHQQSLEIRRQIEDKGGIANSLNNLGNAYESLGQYGEAINFYQQSLEIKLQIEDKGGIANSLGNLGSAYFFLEQYREAINFYQQSLEIQRQIGNRAGEGNSLNNLGYALFQLNQLAPAETFLRQAIEVRESLREGLDDEQKVSLADTQSNSYQTLQRVLIAQNRPQDALEISERGRARAFVELLAARGTVRDESNLASIPAVEPPTIADIQRIAHTQNATLVEYSLVGDNQLYIWVIQPRGEVHFTSVNLQPLHEQNTSLTQLVRNTREKIEKKAESIPELRQLHQLLIEPIAPYLPEDPQARVILLPHGELFLLPFPALQDSTDTYLIQKHTLLTAPAIQALDFSNNPVPLPASPSLALVVGNPTMPQRDPPLSPLRGAQAEAEQIAKLLKTQALTGDAATKTAILPQLSQSPVIHLATHGILDERRGMNSAVVLAPSTPTATSPQYPLLLDHPDGFLTAGEIVELQIPAELVVLSACDTGGGTITGDGVIGLSRAWLTAGTSTVLVSLWKIDDGVSGNMMSQFYQELQNNPDAAAGLRQAMLQAIEANIDLKNWAAFTVIGEAQVPFVGQQSSGFAVSLIELAIVAGVGVGGLVVITQRRRVMPKVVHTLQTVSKTRQIWIPIITGVVLVSGGIMGVQQWLSTPILYENATYGFKMQVPRQWKIQEPQDSITGTVAVFLAPPESGTAQFYEKVSITVEDLSSHPQTLEQYTDKAVQEIRDYVPDAMFLVERDPRTLGNHPAYRVMYTGKMGEKEVQRMLVWIVKEDRAYIVSYESAKGKFDRVLTTVEEMIKSLEFGE
>NC_019693.1|WP_015149161.1|3612923_3613376_+|IS200/IS605-family-transposase
MSLWRLYYHLVWATKKRQPLITPEKETVLYQYIRGKANALRSIVHAIGGTDNHIHIVVSIPPNLSVAEFVKNIKGSSAYHLNHQGFDPNLKFGWQDGYGVFSLGRKQLDIAVNYVHNQKIHHQNNTEIASLEQFSDQDDPPPIWHPRLEA
>NC_019693.1|WP_015149162.1|3614056_3615538_-|protein-kinase
MLGKTLRGRYHILKKLGKGGFGETYLAEDRDLPGTPFCVVKRLFPQSKNPVFLQTAKRLFDKEAEILHRLNPCDRIPRLLAHFQENGEFYLVEDFIDGEDFQKQNPFSPGNPESEVIHLLTEILEILAFVHQQQIIHRDIKPANLMRRQGDGKVFLIDFGAVKEIATLQVNSQGQTIATVAIGTPGYMPSEQAVGNPKPSSDIYALGMVVVELITGIRADQLPKDSRGELCWRNLVNLSEPLAEVLEKMVRYDYRQRFASARETLDAIKNLDKTILPTMPSSASSSQRTKIQGFHPILLVKRALRGEPKEILGLGLTFICTVAAVLSVPQAQQMLFSPPPPLVVQATEFKAYQNAEYQLKLNYPTTWEIDTRRNSITQTLVTFRIPQAELMVTVEDLSSQPKSFDKYTNDFIAQLEANIPDFKKIKEGETTLAQQTGYQVFYTGKQQNIPVQSWQSWTVKGDKAYVFTYSAHSRHYKDHLPTVQAMIESVQID
>NC_019693.1|WP_015149163.1|3615790_3617251_-|DASH-family-cryptochrome
MTYQPIILWYRNDLRVHDHEPLYRALETHAPIVPIYCFDPRQFSKTAYGFPKTGPFRAQFLLESVANLRQSLQNLGSNLIIKIGKPEVILPQIAHQVNASAIYFHQEVTAEEIAVETALSQGVKSLNVALKSFWGHTLYHCDRLPFDIPNIPELFTHFRKQVEKTATPDSCFPTPTQLPPLPEIETGNLPNLTELGVEKVAIASKAVLPFTGGESAGIARMEDYFWTGDRLRTYKETRNGMLGPDYSSKFSPWLSLGCLSPRYIYQQVQDYETQRIKNDSTYWLIFELLWRDYFRFICAKHGNAIFRQSGLQGVTIPWEEDWQKFTLWQQGKTGFPLVDANMRELAATGFMSNRGRQNVASFLTKNLGINWQMGAEWFESLLIDYDVCSNWGNWNYTAGVGNDARGFRFFNIIKQSKDYDPEGDYVKHWLPELAAVPAAKVHEPWKLLEVEQQRFGVKIGVDYPHPVVDLFESAKANEQVYKQQFS
>NC_019693.1|WP_015149164.1|3617559_3619143_-|NADH-quinone-oxidoreductase-subunit-M
MNMAEFPWLTTIILFPIAASLLIPVIPDKDGRTVRWYALIVGLMDFALIVYTFCNHYDLSNPNIQLFESYSWVPALDLNWSVGADGLSMPLIILTGFITTLAILASWPVTLKPKLFFFLILAMYGGQIAVFAVQDMLLFFLVWELELIPVYLLLSIWGGKKRLYAATKFILYTAGGSLFILLAGLAMAFYGDTVTFDMQSLAAKDYAINLELLLYAAFLIAYGVKLPIFPLHTWLPDAHGEATAPVHMLLAGILLKMGGYAIIRMNAQMLPDAHAVFAPMLVILGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLIGIGSFTDLGLSGAVLQMVSHGLIGASLFFMVGATYDRTHTLMLDEMGGIGKKMKKSFAMWTTCSLASLALPGMSGFVAELMVFVGFATSDAYSLTFRVVVVFLAAVGVILTPIYLLSMLREMLYGPENKELVEHEALIDSEPREVFIIACLLVPIIGIGLYPKILTQIYDATTVQLTARLRNSVPTLAEGASVALGEPMEAPAIGSSR
>NC_019693.1|WP_015149165.1|3619743_3621813_-|NAD(P)H-quinone-oxidoreductase-subunit-5
MEPIYQYAWLIPVLPLLAAMLVGLGLISYNKTTNNLRQATAAFLVSSVGAAMVLSFALLWSQIQGHETYTYSLEWAAAGNFHLTMGYTIDHLSALMLAIVTTVALLVMIYTDGYMAHDPGYVRFYTYLSLFSSSMLGLVISPNLVQVYIFWELVGMCSYLLIGFWFDRKPAADACQKAFVTNRVGDFGLLLGMLGLYWATDSFDFQIMGDRLQDLVQSGAIGGGVAALLAVLVFLGPVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGVFLIARMYPVFEHIPSAMTVIAWTGCFTAFLGATIALTQTDIKKGLAYSTMSQLGYMVMAMGIGAYSAGLFHLMTHAYFKAMLFLGSGSVIHGMEEVVGHDPTLAQDMRLMGGLRKFMPITAATFAVGTLAICGIPPFAGFWSKDEILGAAFEANPALWGVGWLTAGMTAFYMFRMYFMTFEGPFRGNDTEIRHELKTEAEAGEPILAFGPGAMDPRELEASHDDHSHGHHSEYPHESPLSMTFPLMALAVPSALLGLVGTPFANYFEAFIHPPSESLAEIAEHAEEFNLTEFLVMGGSSVGIALLGITLASLMYLSRKIDPKAIASQIKPLYLLSRKKWYFDEIYNSLFVLGSRRLARQVMEVDYRVVDGAVNLTGLITVISGEGLKYFENGRAQFYALIVFVAVLGLVILSGVT
>NC_019693.1|WP_015149167.1|3622129_3622288_-|hypothetical-protein
MRISRQEFFTAIRFFLGQDLRIWGGQTRNVAAIRESPLRFGVYLIDRVSPVD
>NC_019693.1|WP_015149168.1|3622287_3622659_-|thiol-reductase-thioredoxin
MVLSLNERSFKQEVLEATTPVLVNFWAPWCGICLLINPVLKGFEAEWGETVKIVGINADQTLKLASTYRIATLPTLILFDGGSIIHRIEGFQGRDDLTRELRSLLLTTQKSHSYSQLQPAINS
>NC_019693.1|WP_015149169.1|3623682_3624078_+|hypothetical-protein
MAETATALRGKALLKKAKELANLPRRELAKACGYYTTTKGGETRVNLTDFYDALLEARGIALDPEAKKSTRGREASYRVSVHQNGQLVIGSTYTQAMGLKPGDEFEIKLGYKHIHLIQVDESDKDGETEAA

Crispr_ID: NC_019693_31

• CRISPR_ID: NC_019693_31
• CRISPR_location: 3619512-3619610
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_31

Consensus_repeat	Method
GATTGAGTATTAGCCCGCGCAGG	CRISPRCasFinder

spacers of NC_019693_31

>31.1|3619535|53|NC_019693|CRISPRCasFinder
CGGGCTTCGTCCTGTGAGCCTCCACCCTTGAGGGTGCGGGTTTTATCCAACCA

CRISPR arrays and Neighbor proteins around NC_019693_31

CRISPR arrays

The CRISPR arrays of NC_019693_31

>merge|NC_019693|31|3619512-3619610|CRISPRCasFinder
GATTGAGTATTAGCCCGCGCAGGCGGGCTTCGTCCTGTGAGCCTCCACCCTTGAGGGTGCGGGTTTTATCCAACCAGATTCAGTATTAGCCCGCGCAGG

>NC_019693|31|31|3619512-3619610|CRISPRCasFinder
GATTGAGTATTAGCCCGCGCAGG	CGGGCTTCGTCCTGTGAGCCTCCACCCTTGAGGGTGCGGGTTTTATCCAACCA
GATTCAGTATTAGCCCGCGCAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_156823846.1|3624349_3624532_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149168.1|3622287_3622659_-|thiol-reductase-thioredoxin	unknown	unknown	gnl|CDD|200072
NC_019693.1|WP_015149170.1|3624749_3625217_-|VOC-family-protein	unknown	unknown	gnl|CDD|319898
NC_019693.1|WP_015149173.1|3628128_3629010_+|membrane-protease-subunit,-stomatin/prohibitin	unknown	unknown	gnl|CDD|259799
NC_019693.1|WP_015149156.1|3602465_3603203_-|WecB/TagA/CpsF-family-glycosyltransferase	unknown	unknown	gnl|CDD|224833
NC_019693.1|WP_015149157.1|3603450_3606801_+|glycosyl-hydrolase-family-15	unknown	unknown	gnl|CDD|366266
NC_019693.1|WP_015149174.1|3629056_3629245_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149155.1|3600401_3602300_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224048
NC_019693.1|WP_015149167.1|3622129_3622288_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149158.1|3607129_3607825_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NC_019693.1|WP_015149172.1|3626164_3627481_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149161.1|3612923_3613376_+|IS200/IS605-family-transposase	unknown	unknown	gnl|CDD|376616
NC_019693.1|WP_015149163.1|3615790_3617251_-|DASH-family-cryptochrome	unknown	unknown	gnl|CDD|274288
NC_019693.1|WP_015149164.1|3617559_3619143_-|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl|CDD|235050
NC_019693.1|WP_015149160.1|3608794_3612280_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|378942
NC_019693.1|WP_015149171.1|3625387_3626089_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_019693.1|WP_015149159.1|3608146_3608647_-|hypothetical-protein	unknown	unknown	gnl|CDD|372967
NC_019693.1|WP_015149165.1|3619743_3621813_-|NAD(P)H-quinone-oxidoreductase-subunit-5	unknown	unknown	gnl|CDD|236005
NC_019693.1|WP_015149162.1|3614056_3615538_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_019693.1|WP_015149169.1|3623682_3624078_+|hypothetical-protein	unknown	unknown	gnl|CDD|372980

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015149168.1|3622287_3622659_-|thiol-reductase-thioredoxin	gnl|CDD|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	4.82289e-28
NC_019693.1|WP_015149170.1|3624749_3625217_-|VOC-family-protein	gnl|CDD|319898	cd06587, VOC, vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). Type I extradiol dioxygenases catalyze the incorporation of both atoms of molecular oxygen into aromatic substrates, which results in the cleavage of aromatic rings. They are key enzymes in the degradation of aromatic compounds. Type I extradiol dioxygenases include class I and class II enzymes. Class I and II enzymes show sequence similarity; the two-domain class II enzymes evolved from a class I enzyme through gene duplication. Glyoxylase I catalyzes the glutathione-dependent inactivation of toxic methylglyoxal, requiring zinc or nickel ions for activity. The antibiotic resistance proteins in this family use a variety of mechanisms to block the function of antibiotics. Bleomycin resistance protein (BLMA) sequesters bleomycin's activity by directly binding to it. Whereas, three types of fosfomycin resistance proteins employ different mechanisms to render fosfomycin inactive by modifying the fosfomycin molecule. Although the proteins in this superfamily are functionally distinct, their structures are similar. The difference among the three dimensional structures of the three types of proteins in this superfamily is interesting from an evolutionary perspective. Both glyoxalase I and BLMA show domain swapping between subunits. However, there is no domain swapping for type 1 extradiol dioxygenases.	2.06597e-17
NC_019693.1|WP_015149173.1|3628128_3629010_+|membrane-protease-subunit,-stomatin/prohibitin	gnl|CDD|259799	cd03401, SPFH_prohibitin, Prohibitin family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model characterizes proteins similar to prohibitin (a lipid raft-associated integral membrane protein). Individual proteins of the SPFH (band 7) domain superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. These microdomains, in addition to being stable scaffolds, may also be dynamic units with their own regulatory functions. Prohibitin is a mitochondrial inner-membrane protein which may act as a chaperone for the stabilization of mitochondrial proteins. Human prohibitin forms a hetero-oligomeric complex with Bap-37 (prohibitin 2, an SPFH domain carrying homolog). This complex may protect non-assembled membrane proteins against proteolysis by the m-AAA protease. Prohibitin and Bap-37 yeast homologs have been implicated in yeast longevity and in the maintenance of mitochondrial morphology.	3.70339e-61
NC_019693.1|WP_015149156.1|3602465_3603203_-|WecB/TagA/CpsF-family-glycosyltransferase	gnl|CDD|224833	COG1922, WecG, Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane].	4.52506e-80
NC_019693.1|WP_015149157.1|3603450_3606801_+|glycosyl-hydrolase-family-15	gnl|CDD|366266	pfam00723, Glyco_hydro_15, Glycosyl hydrolases family 15. In higher organisms this family is represented by phosphorylase kinase subunits.	4.33381e-77
NC_019693.1|WP_015149155.1|3600401_3602300_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0
NC_019693.1|WP_015149158.1|3607129_3607825_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	3.17567e-28
NC_019693.1|WP_015149161.1|3612923_3613376_+|IS200/IS605-family-transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	6.5292e-35
NC_019693.1|WP_015149163.1|3615790_3617251_-|DASH-family-cryptochrome	gnl|CDD|274288	TIGR02765, deoxyribodipyrimidine_photolyase, cryptochrome, DASH family. Photolyases and cryptochromes are related flavoproteins. Photolyases harness the energy of blue light to repair DNA damage by removing pyrimidine dimers. Cryptochromes do not repair DNA and are presumed to act instead in some other (possibly unknown) process such as entraining circadian rhythms. This model describes the cryptochrome DASH subfamily, one of at least five major subfamilies, which is found in plants, animals, marine bacteria, etc. Members of this family bind both folate and FAD. They may show weak photolyase activity in vitro but have not been shown to affect DNA repair in vivo. Rather, DASH family cryptochromes have been shown to bind RNA (Vibrio cholerae VC1814), or DNA, and seem likely to act in light-responsive regulatory processes. [Cellular processes, Adaptations to atypical conditions].	0
NC_019693.1|WP_015149164.1|3617559_3619143_-|NADH-quinone-oxidoreductase-subunit-M	gnl|CDD|235050	PRK02546, PRK02546, NAD(P)H-quinone oxidoreductase subunit 4; Provisional.	0
NC_019693.1|WP_015149160.1|3608794_3612280_-|tetratricopeptide-repeat-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	1.44438e-67
NC_019693.1|WP_015149171.1|3625387_3626089_-|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	1.52488e-11
NC_019693.1|WP_015149159.1|3608146_3608647_-|hypothetical-protein	gnl|CDD|372967	pfam14218, COP23, Circadian oscillating protein COP23. This family includes the circadian oscillating protein COP23 from Cyanothece sp. (strain PCC 8801). The levels of this peripheral membrane protein display a circadian oscillation.	1.01226e-44
NC_019693.1|WP_015149165.1|3619743_3621813_-|NAD(P)H-quinone-oxidoreductase-subunit-5	gnl|CDD|236005	PRK07376, PRK07376, NADH-quinone oxidoreductase subunit L.	0
NC_019693.1|WP_015149162.1|3614056_3615538_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.39562e-61
NC_019693.1|WP_015149169.1|3623682_3624078_+|hypothetical-protein	gnl|CDD|372980	pfam14250, AbrB-like, AbrB-like transcriptional regulator. This family of DNA-binding proteins is likely to act as a transcriptional regulator. This family does not include E.coli AbrB, which belongs to pfam05145.	3.64625e-41

Protein sequences

>NC_019693.1|WP_015149164.1|3617559_3619143_-|NADH-quinone-oxidoreductase-subunit-M
MNMAEFPWLTTIILFPIAASLLIPVIPDKDGRTVRWYALIVGLMDFALIVYTFCNHYDLSNPNIQLFESYSWVPALDLNWSVGADGLSMPLIILTGFITTLAILASWPVTLKPKLFFFLILAMYGGQIAVFAVQDMLLFFLVWELELIPVYLLLSIWGGKKRLYAATKFILYTAGGSLFILLAGLAMAFYGDTVTFDMQSLAAKDYAINLELLLYAAFLIAYGVKLPIFPLHTWLPDAHGEATAPVHMLLAGILLKMGGYAIIRMNAQMLPDAHAVFAPMLVILGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLIGIGSFTDLGLSGAVLQMVSHGLIGASLFFMVGATYDRTHTLMLDEMGGIGKKMKKSFAMWTTCSLASLALPGMSGFVAELMVFVGFATSDAYSLTFRVVVVFLAAVGVILTPIYLLSMLREMLYGPENKELVEHEALIDSEPREVFIIACLLVPIIGIGLYPKILTQIYDATTVQLTARLRNSVPTLAEGASVALGEPMEAPAIGSSR
>NC_019693.1|WP_015149163.1|3615790_3617251_-|DASH-family-cryptochrome
MTYQPIILWYRNDLRVHDHEPLYRALETHAPIVPIYCFDPRQFSKTAYGFPKTGPFRAQFLLESVANLRQSLQNLGSNLIIKIGKPEVILPQIAHQVNASAIYFHQEVTAEEIAVETALSQGVKSLNVALKSFWGHTLYHCDRLPFDIPNIPELFTHFRKQVEKTATPDSCFPTPTQLPPLPEIETGNLPNLTELGVEKVAIASKAVLPFTGGESAGIARMEDYFWTGDRLRTYKETRNGMLGPDYSSKFSPWLSLGCLSPRYIYQQVQDYETQRIKNDSTYWLIFELLWRDYFRFICAKHGNAIFRQSGLQGVTIPWEEDWQKFTLWQQGKTGFPLVDANMRELAATGFMSNRGRQNVASFLTKNLGINWQMGAEWFESLLIDYDVCSNWGNWNYTAGVGNDARGFRFFNIIKQSKDYDPEGDYVKHWLPELAAVPAAKVHEPWKLLEVEQQRFGVKIGVDYPHPVVDLFESAKANEQVYKQQFS
>NC_019693.1|WP_015149162.1|3614056_3615538_-|protein-kinase
MLGKTLRGRYHILKKLGKGGFGETYLAEDRDLPGTPFCVVKRLFPQSKNPVFLQTAKRLFDKEAEILHRLNPCDRIPRLLAHFQENGEFYLVEDFIDGEDFQKQNPFSPGNPESEVIHLLTEILEILAFVHQQQIIHRDIKPANLMRRQGDGKVFLIDFGAVKEIATLQVNSQGQTIATVAIGTPGYMPSEQAVGNPKPSSDIYALGMVVVELITGIRADQLPKDSRGELCWRNLVNLSEPLAEVLEKMVRYDYRQRFASARETLDAIKNLDKTILPTMPSSASSSQRTKIQGFHPILLVKRALRGEPKEILGLGLTFICTVAAVLSVPQAQQMLFSPPPPLVVQATEFKAYQNAEYQLKLNYPTTWEIDTRRNSITQTLVTFRIPQAELMVTVEDLSSQPKSFDKYTNDFIAQLEANIPDFKKIKEGETTLAQQTGYQVFYTGKQQNIPVQSWQSWTVKGDKAYVFTYSAHSRHYKDHLPTVQAMIESVQID
>NC_019693.1|WP_015149161.1|3612923_3613376_+|IS200/IS605-family-transposase
MSLWRLYYHLVWATKKRQPLITPEKETVLYQYIRGKANALRSIVHAIGGTDNHIHIVVSIPPNLSVAEFVKNIKGSSAYHLNHQGFDPNLKFGWQDGYGVFSLGRKQLDIAVNYVHNQKIHHQNNTEIASLEQFSDQDDPPPIWHPRLEA
>NC_019693.1|WP_015149160.1|3608794_3612280_-|tetratricopeptide-repeat-protein
MSRFLPPLPSKRTGQKSPVLLSVVLLSVALSLVSSPQVSELRLSASPTPGETSEAEEAEADRLLIQGSQQYNRSDLRGAIQSWKTALAIYQQLENRPGISDSLNNLGAAYTNLGQYREAINFYQQSLAIKRQLEDKRGIVASLNNLGLAYDSLGQYREAINFHQQSLEIKRQIEDKGGIANSLNNLGNAYNSLGQYREAINFHQQSLEIKRQIEDKGGIANSLNNLGAAYTNLGQYREAINFHQQSLEIKRQIEDKGGIANSLDNLGVAYNSLGQYREAINFYQQSLEIRRQIEDKGGIAGSLNNLGESYRYLGQYREAINFYQQSLEIQRQIEDKGGIANSLNNLGIVYNSLGQYREAINFHQQSLEIRRQIEDKGGIANSLNNLGNAYESLGQYGEAINFYQQSLEIKLQIEDKGGIANSLGNLGSAYFFLEQYREAINFYQQSLEIQRQIGNRAGEGNSLNNLGYALFQLNQLAPAETFLRQAIEVRESLREGLDDEQKVSLADTQSNSYQTLQRVLIAQNRPQDALEISERGRARAFVELLAARGTVRDESNLASIPAVEPPTIADIQRIAHTQNATLVEYSLVGDNQLYIWVIQPRGEVHFTSVNLQPLHEQNTSLTQLVRNTREKIEKKAESIPELRQLHQLLIEPIAPYLPEDPQARVILLPHGELFLLPFPALQDSTDTYLIQKHTLLTAPAIQALDFSNNPVPLPASPSLALVVGNPTMPQRDPPLSPLRGAQAEAEQIAKLLKTQALTGDAATKTAILPQLSQSPVIHLATHGILDERRGMNSAVVLAPSTPTATSPQYPLLLDHPDGFLTAGEIVELQIPAELVVLSACDTGGGTITGDGVIGLSRAWLTAGTSTVLVSLWKIDDGVSGNMMSQFYQELQNNPDAAAGLRQAMLQAIEANIDLKNWAAFTVIGEAQVPFVGQQSSGFAVSLIELAIVAGVGVGGLVVITQRRRVMPKVVHTLQTVSKTRQIWIPIITGVVLVSGGIMGVQQWLSTPILYENATYGFKMQVPRQWKIQEPQDSITGTVAVFLAPPESGTAQFYEKVSITVEDLSSHPQTLEQYTDKAVQEIRDYVPDAMFLVERDPRTLGNHPAYRVMYTGKMGEKEVQRMLVWIVKEDRAYIVSYESAKGKFDRVLTTVEEMIKSLEFGE
>NC_019693.1|WP_015149159.1|3608146_3608647_-|hypothetical-protein
MSKQKNGVVFSILVILQGVLSACQPVESLPRGTDYSCDLTQNPPVTIARTSVKGDMPVIAWKSTFFEGSGYTPEKRCLEVSERLQTYYQMGLLHYLTTGVQDNQNIICVTRTHGGDCSGLLLTLEPGDNPEQVLKDLVNNQGRMIERSEGTGGKLYIELIPELQSP
>NC_019693.1|WP_015149158.1|3607129_3607825_-|Uma2-family-endonuclease
MTTISVLNTPPLESGDRLTRDEFEHRYHAAPEITKAELVEGVVFVASPVRANRHGRPHALIMAWLSAYWTGTPGVWCYDNATVRLDEENEPQPDALLRLEPAVGGNSSITEDDYIEGAPELIVEIAASSASYDLNDKLNAYQRNGVQEYIVWQIYENKLDWFILEEGRYVALVPDEQGILRSQVFPGLWLSVEALRQRNVVQVVAVVQQGLQTAEHQEFVQRLAQQKPAGD
>NC_019693.1|WP_015149157.1|3603450_3606801_+|glycosyl-hydrolase-family-15
MTLTSSERQTRLDYYYHQIQSLILVRQNPITGLLPASTAINAHGDYTDAWVRDNVYSILAVWGLALAYRKMDDSQGRTYELEHSVVKLMRGLLFCMMRQADKVERFKETQSLLDCLHAKFDTHTGDTVVGDNEWGHLQIDATSIFLLMLAQMSVSGLSIIYTVDEVNFIQNLVYYIGRAYRTPDYGIWERGNKINKGNPELNASSIGMALAALEAINGVNLFGVKGSQSSVIHVLADEIARARQTLESILPRESSSKEVDAALLSIITFPAFAIEDGPLCDRTKQKVITKLQGKYGCKRFLRDGHQTVLEDPWRLHYEPWELKKFENIECEWPLFFTYLFLDGIFRGDRSQTEEYRERLNSLVVESYGLKLLPELYYIPADKVEAERTNPQTQPRLPNENLPLVWAQSLYFLGLMLDEGLLHRGDIDPLGRRRTLAGRRKPVVQIALLAEDEDLQTELAYHGIATQTPAEVEPLQVRKARDLSGVYRQIGRNDKFGLTGRPVRRLRSLTTSNIFRIRGETIVFLPSFLDQQEFYLTLDYHFLVSNIKGELAYIHRHWWRYPQIGGHGVGRPTVTLLLTHAMLETDGSSEGFLPALLELMKELRDGDCEGTPVKLGRLNQLMLTGSIERIDFLHEFQFSENPVQNAAPACYFLAYDAEKNWPLSHTQEFMLECETDPGLLLDSLRSSFNLYEQIELLHTLSRLRGLEFETGLAGPGRPVTVADLLNEVYFKAGTGKAIGDCAIAGSPKRKTTRTEANSTENAAEKQIHWSVVRRAAGLLNKVDIGLSDAVTDILVRQKQITVGKAYTEASLISRPMSYTEIVDKIRQFCGEDIRDRVLTQEILLYLGLLIKAEPDLFNGLLTLRVSYLILLITSELAKELNLTQDEAYERVMELSPFEINNRLREVLKGYAGMNKLLKKQESLHVQQQEQEIEWVVLPSPNETEEISGNWQRRRQLDGAAGRVPKEFYPRVWQVMQHCKGLVIGDKLERRNRLDSELILAEMTPGEKNFALRVEHLLNKIQAPEYRQVNIETLMELAAICDRNPDLQIQEYIVLDVLIGHAVRLAWIESHPERSDFYDEDKALAWPSFYNTSPYVCASFVVKAFRYLTKFGKAIAVG
>NC_019693.1|WP_015149156.1|3602465_3603203_-|WecB/TagA/CpsF-family-glycosyltransferase
MLQVLQKFSVLGLPVHITTHYRDWLQSRLQQRQGTHVVTLNAEMAMQALENLDLAEVIHQADLVIPDGAGVVFYFLVRGRKIQRCPGIELAESLVQLAGDLGEDCSTFFFGGKPGIAEIAAKRWQTELPALAIAGTQDGYLSPEDEPAFKARLQQLQPRLILVGLGVPRQEFWIRENRHLCPDAIWVGVGGSFDIWSGQKERAPVWLQRLQMEWAYRLYQEPWRWRRMLALPHFAWISMKTALRQ
>NC_019693.1|WP_015149155.1|3600401_3602300_+|ABC-transporter-ATP-binding-protein
MTDTVLDVRNLQVQFFTEGRPVKAVDQISFTVQRGQTVGIVGESGSGKSVTSLAVMGLVPTPGRISGGEIWFRGTQEEDPIDLLALPPQAKQQYRGGKISMIFQEPMSSLNPVYNIGFQLTEAILLHHQISESEARRRAIAALQEVKLLPSDAELREQVQLPETATEREIMQQVNQQKLAILKRYPHELSGGQIQRVMIAMAISCDPTLLIADEPTTALDVTVQARILELMRDLRDRRGMSMMFITHDLGVIAEIADQVAVMYQGKIVEQGSVLQIFSNPQHPYTKGLLACRPRPDRRLIYLPTVSDFMEVVTNANGDREIREKHSETHDSLDGVTNIQEVSETDVKQRLTDLQQKSPLLEVRNLEVAFPVRGVFGETQRYIMAVNGVSFEVYPGETLGLVGESGCGKTTLARTLLRLIEPTAGKVLFEGQDVGKLEGRALRQVRREMQIVFQNPFSSLNPRMSIGNLVMEPLKIHGVGESARHRRERSAYLLERVGLNAELMNRYPHEFSGGQRQRICIARALALNPKFIICDESVSALDVSVQAQVLNLLKELQEEFKLTYIFISHDLSVVKFMSDRILVMNKGKIEEVGPAESIYSDPQQDYTRSLISSIPTGTLDRIQEQQAQRQVSA
>NC_019693.1|WP_015149165.1|3619743_3621813_-|NAD(P)H-quinone-oxidoreductase-subunit-5
MEPIYQYAWLIPVLPLLAAMLVGLGLISYNKTTNNLRQATAAFLVSSVGAAMVLSFALLWSQIQGHETYTYSLEWAAAGNFHLTMGYTIDHLSALMLAIVTTVALLVMIYTDGYMAHDPGYVRFYTYLSLFSSSMLGLVISPNLVQVYIFWELVGMCSYLLIGFWFDRKPAADACQKAFVTNRVGDFGLLLGMLGLYWATDSFDFQIMGDRLQDLVQSGAIGGGVAALLAVLVFLGPVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGVFLIARMYPVFEHIPSAMTVIAWTGCFTAFLGATIALTQTDIKKGLAYSTMSQLGYMVMAMGIGAYSAGLFHLMTHAYFKAMLFLGSGSVIHGMEEVVGHDPTLAQDMRLMGGLRKFMPITAATFAVGTLAICGIPPFAGFWSKDEILGAAFEANPALWGVGWLTAGMTAFYMFRMYFMTFEGPFRGNDTEIRHELKTEAEAGEPILAFGPGAMDPRELEASHDDHSHGHHSEYPHESPLSMTFPLMALAVPSALLGLVGTPFANYFEAFIHPPSESLAEIAEHAEEFNLTEFLVMGGSSVGIALLGITLASLMYLSRKIDPKAIASQIKPLYLLSRKKWYFDEIYNSLFVLGSRRLARQVMEVDYRVVDGAVNLTGLITVISGEGLKYFENGRAQFYALIVFVAVLGLVILSGVT
>NC_019693.1|WP_015149167.1|3622129_3622288_-|hypothetical-protein
MRISRQEFFTAIRFFLGQDLRIWGGQTRNVAAIRESPLRFGVYLIDRVSPVD
>NC_019693.1|WP_015149168.1|3622287_3622659_-|thiol-reductase-thioredoxin
MVLSLNERSFKQEVLEATTPVLVNFWAPWCGICLLINPVLKGFEAEWGETVKIVGINADQTLKLASTYRIATLPTLILFDGGSIIHRIEGFQGRDDLTRELRSLLLTTQKSHSYSQLQPAINS
>NC_019693.1|WP_015149169.1|3623682_3624078_+|hypothetical-protein
MAETATALRGKALLKKAKELANLPRRELAKACGYYTTTKGGETRVNLTDFYDALLEARGIALDPEAKKSTRGREASYRVSVHQNGQLVIGSTYTQAMGLKPGDEFEIKLGYKHIHLIQVDESDKDGETEAA
>NC_019693.1|WP_156823846.1|3624349_3624532_+|hypothetical-protein
MGLQGKTLTDGMPSFRWMEWKSLSRSRKASLFKEVVHGGISEAISEVSSTGNLVDDSGKD
>NC_019693.1|WP_015149170.1|3624749_3625217_-|VOC-family-protein
MQINLESPTFAIAPGSLRQVHHIAFNVRDLAASRHFYGRILGLQELTGESVPTTLRELVATGKVANFVTPDGTVIDLFYEPDLLPPDPDPKRAFTRANHLAFDIDPQLFDGAVEALKAHQVAIDSGPVTRPTGRGIYFYDPDGFIIEIRCNPLDS
>NC_019693.1|WP_015149171.1|3625387_3626089_-|Uma2-family-endonuclease
MVIEVRSPEPQATGIYPNPDGQPMADNTQQFALIVWIKENLERVYAQDPNVFVSGDLLWYPVEGNNKLRQAPDVMVAFGRPKGYRESYQQWKEDNIPPQVVFEIGSPRSRPSEMGKKLAFYQNYGVEEYYLYYPDWLDLAGWCKGEGRLHLIEQMEGWVSPRLGVRFQMAQTGLQLYRPDGEPFLTTLELLEERALQAEERARQAESELERERQKSLLLADRLRSMGIDPMEL
>NC_019693.1|WP_015149172.1|3626164_3627481_-|hypothetical-protein
MLEINAPNLYLFSYHLKEGLGISLESSQGNYRSVVEKIVGDLSRLIPDAIAEDYQETFLDLQTQPTADLKFKGTLHNHTILGRYLRRTLHQTYALIFDGSVQERYNAHQVQSLLSTLKALTPDPHSPNNLGQTWLISGVWEHGNSTQIEKLAEESYKTLISPEGWHHRATGDYVGVKLYEFWRTSGGNTGETIEGNSYLLLVLYPDHETFQAGWGFYEQWQQVFLSRHQIIWADWQSQHLKQQLIDKYQQIEAIADYSDLTLYHLKTTRDTLSGLITGFTTLEMYLNLMEIHLDHYDQYCHQLEQDADGLGSTDLTFLNQFSASVKQTYLPRLQGDINAFRLNWERIQHLTHMIQGLVEIRQAQRDRTVKTAVAIGGVGVVTGCIVAVASSTHPPVPSVNPGTNSAGLSGVLLLSVICGGVASLVTFVALSLWQKLGK
>NC_019693.1|WP_015149173.1|3628128_3629010_+|membrane-protease-subunit,-stomatin/prohibitin
MTFIATILTSLLSILVVLVGPKFSDEKHRNTVRAVALLIGILAATVSLLKTFTIIPSGKVGVIEVFGKVSSQPLSPGVHWVNPFGNVLKFSTRLRDMPEKISATSQEGLNLVVEGTIQYRLDPNSAADVYQNVGVNDGEIVRSRFQAIMREITASYPARDIYTAKREEVTRRLRLSMRESLTPLGFVVEEAFLKDVALPEKLQAAIEQKMEVEQDNQRMELVLQKEQQEAERKRIEALGIADYQQIISPGLTSQFLQWRSIEATDRLANSNNSKVVIMGGSGNNATVPVILQP
>NC_019693.1|WP_015149174.1|3629056_3629245_+|hypothetical-protein
MAEPPKYYIVKGKNGTCEIIPGSRLEGPDQEELKEKWGPFESREEATARRVGLIRAGKCQPL

Crispr_ID: NC_019693_32

• CRISPR_ID: NC_019693_32
• CRISPR_location: 3679889-3680006
• CRISPR_type: TypeV-U4
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: c2c9_V-U4

Consensus repeat of NC_019693_32

Consensus_repeat	Method
CCGGTTTCTGGGTCCCTTGCCGTAGGTTGAGA	CRISPRCasFinder

spacers of NC_019693_32

>32.1|3679921|54|NC_019693|CRISPRCasFinder
CAGCGGGTTTGTTTCCTGCATTTTGGGTGTTCGGGCAACATTTATGCACCAAAC

CRISPR arrays and Neighbor proteins around NC_019693_32

CRISPR arrays

The CRISPR arrays of NC_019693_32

>merge|NC_019693|32|3679889-3680006|CRISPRCasFinder
CCGGTTTCTGGGTCCCTTGCCGTAGGTTGAGACAGCGGGTTTGTTTCCTGCATTTTGGGTGTTCGGGCAACATTTATGCACCAAACCCGGTTTCTGGGTCCCTTGCCGTAGGTTGAGA

>NC_019693|32|32|3679889-3680006|CRISPRCasFinder
CCGGTTTCTGGGTCCCTTGCCGTAGGTTGAGA	CAGCGGGTTTGTTTCCTGCATTTTGGGTGTTCGGGCAACATTTATGCACCAAAC
CCGGTTTCTGGGTCCCTTGCCGTAGGTTGAGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015149217.1|3688680_3689199_+|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl|CDD|236483
NC_019693.1|WP_015149213.1|3685313_3686039_+|C40-family-peptidase	unknown	unknown	gnl|CDD|366353
NC_019693.1|WP_015149212.1|3683647_3684775_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c9_V-U4	-	gnl|CDD|223747
NC_019693.1|WP_015149211.1|3682659_3683595_-|hypothetical-protein	unknown	unknown	gnl|CDD|379138
NC_019693.1|WP_015149216.1|3687234_3688494_+|MFS-transporter	unknown	unknown	gnl|CDD|341042
NC_019693.1|WP_015149204.1|3671510_3671693_-|30S-ribosomal-protein-S21	unknown	unknown	gnl|CDD|234707
NC_019693.1|WP_015149206.1|3675682_3676729_+|acyltransferase	unknown	unknown	gnl|CDD|224748
NC_019693.1|WP_015149207.1|3676767_3677916_-|family-10-glycosylhydrolase	unknown	unknown	gnl|CDD|251441
NC_019693.1|WP_044195167.1|3678044_3679319_-|glycosyltransferase-family-1-protein	unknown	unknown	gnl|CDD|340830
NC_019693.1|WP_044195169.1|3681251_3681470_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149200.1|3668576_3668762_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149202.1|3669974_3670742_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149218.1|3689195_3689726_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149203.1|3670946_3671414_+|SsrA-binding-protein-SmpB	unknown	unknown	gnl|CDD|235455
NC_019693.1|WP_015149209.1|3680396_3681233_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149205.1|3672581_3675269_+|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|236645
NC_019693.1|WP_015149199.1|3666784_3668527_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|274350
NC_019693.1|WP_015149219.1|3690037_3690289_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149201.1|3669126_3669450_-|DUF4278-domain-containing-protein	unknown	unknown	gnl|CDD|372912
NC_019693.1|WP_156823850.1|3681671_3682385_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_015149212.1|3683647_3684775_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c9_V-U4	-	7.8e-95	313.1	1.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015149213.1|3685313_3686039_+|C40-family-peptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	5.23146e-34
NC_019693.1|WP_015149217.1|3688680_3689199_+|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl|CDD|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	7.38751e-99
NC_019693.1|WP_015149216.1|3687234_3688494_+|MFS-transporter	gnl|CDD|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.04438e-83
NC_019693.1|WP_015149204.1|3671510_3671693_-|30S-ribosomal-protein-S21	gnl|CDD|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	9.6105e-12
NC_019693.1|WP_015149206.1|3675682_3676729_+|acyltransferase	gnl|CDD|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	1.21419e-11
NC_019693.1|WP_015149207.1|3676767_3677916_-|family-10-glycosylhydrolase	gnl|CDD|251441	pfam02638, GHL10, Glycosyl hydrolase-like 10. This is family of bacterial glycosyl-hydrolase-like proteins falling into the family GHL10 as described above,.	5.70302e-65
NC_019693.1|WP_044195167.1|3678044_3679319_-|glycosyltransferase-family-1-protein	gnl|CDD|340830	cd03800, GT4_sucrose_synthase, sucrose-phosphate synthase and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.	9.96331e-163
NC_019693.1|WP_015149211.1|3682659_3683595_-|hypothetical-protein	gnl|CDD|379138	pfam13354, Beta-lactamase2, Beta-lactamase enzyme family. This family is closely related to Beta-lactamase, pfam00144, the serine beta-lactamase-like superfamily, which contains the distantly related pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	2.15556e-16
NC_019693.1|WP_015149203.1|3670946_3671414_+|SsrA-binding-protein-SmpB	gnl|CDD|235455	PRK05422, smpB, SsrA-binding protein SmpB.	7.39843e-86
NC_019693.1|WP_015149212.1|3683647_3684775_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl|CDD|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.96154e-52
NC_019693.1|WP_015149205.1|3672581_3675269_+|EAL-domain-containing-protein	gnl|CDD|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	8.64586e-129
NC_019693.1|WP_015149199.1|3666784_3668527_-|tetratricopeptide-repeat-protein	gnl|CDD|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	1.02407e-31
NC_019693.1|WP_015149201.1|3669126_3669450_-|DUF4278-domain-containing-protein	gnl|CDD|372912	pfam14105, DUF4278, Domain of unknown function (DUF4278). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are typically between 58 and 136 amino acids in length. There is a single completely conserved residue R that may be functionally important.	2.40399e-23

Protein sequences

>NC_019693.1|WP_044195167.1|3678044_3679319_-|glycosyltransferase-family-1-protein
MAVKANKHIALISVHGDPAVEIGKEEAGGQNVYVRQVGEALAKQGWQVDMFTRKANAEDPTVVEHAPNCRTIRLVAGPESFVPRQEIFEYLPTFVEALIQFQQQAGIEYKLVHTNYWLSAWVGMELKKKQGVKQVHVYHSLGAVKYKSIATIPTIATTRLGVEKAVLETSERIVATSPQEQEHMKTLVSQKGTIQIIPCGTDIHRFGSIQRQEARSALGIGPEKKVVLYVGRFDSRKGIETLVRGVARSQSRENANLSLIIAGGSRPGQSDGIERDRIEAIVDELGLRQITQFPGRIGDELLPQYYAAADICVVPSHYEPFGLVAIEAMASRTPVIASDVGGLQFSVKAEETGLLCPPQDDAAFAEAIDRILSNPTWGDRLGEASRQRVENLFSWDGVATQLGELYQELLTETLIEPQLEKAIA
>NC_019693.1|WP_015149207.1|3676767_3677916_-|family-10-glycosylhydrolase
MEIRGVWMTTTDSQVFRSQERINEAVAFLAETGFNVIFPVVWTKGLTLYPSRVLKQTFGIEIDPLYQGRDPLAELIEAAKSSGIAVIPWFEYGFASSYQSNGGMLLQKKPAWAAKDLSGNLLNKNGFEWMNALHPEVQNFLLQLILEVVQNYPVAGIQGDDRLPAFPREGGYDEFTRNLYRQTFQCDPPSNCQDSQWLQWRADLLTEFLSQLYQQIKAINPNLLVSLSPNIYPWCLNEYLQDSQTWLNRGLTDLMHPQIYRRDFQSYQRVVNQMVKSPCFSEQLPRISPGILIKLGKYRISPEYLLSAIDYNRACGLPGEVLFFYEGLREDDNALAKPLRSRYSSPVPFPTALELTQGVANQPAERKNPRGSGWLDWLKSRF
>NC_019693.1|WP_015149206.1|3675682_3676729_+|acyltransferase
MGEKFYFPKLDAIRGAACFYILIHNFIYGLYSLELVPDFVKLIFAAGQEAVIVFFILSGFLVRFSLARHPELSFWKYLVKRFKRIYFPLIISMLLSVMILAWDGTLLQKLSGVDIIGNFLLLQDFGSVKPGTWFYPFLGNLPLWSLSYEWWFYLMFYPLIHWVTNTTQRIYSILLFSAVSYGIYVLWPNQISLICSYFIVGWVGVEMANLFLKYRTFTFKNMQPILLSLLGMVLISAIPLFWESELKFGYYPFLMFRHFVAAFLLVMGGLYWYRHQLIYFNYILGYFSILAPISYGIYIFSYPILIQWGLNSSLPKNWAFYGLNLMILIGLAYLTERKWQPAIDRWIK
>NC_019693.1|WP_015149205.1|3672581_3675269_+|EAL-domain-containing-protein
MIRRKIKRHSTIILDRENLLNRIASRIRQSLELNEILETTAREIRAFLNTHRVKIYRFEEDGSGEVIAESIQDDRLPSMLGLRFPATDIPVKSRELFLTARQRVIVDVVSGRKTTEELDFSDNGESISRGGIRYWPVDPCHSEYLTNMGVSSSLAIPILHQHHLWGLLVSHHGKPRRYSEREIEVVQLLVDQMSIAIAQSDLLNRTRHQAHDEAVLNKISGLLHSPLDLKKIRQTVLKETVLALRADAGRLYINPDLTGAPAQIYTYGIQPSIAWIEETDCWQQLINGGDPIAPAATKPETPQKEILFPPEQGTIYKYGMDLSADLNGYSESSSSPHSMVYLHSVSIGNIYNFPAFNPLVYAFQATRIRSVLIVPLKYNKQYLGCLTLFRNEIETATLWAGRNDWDERNRRPRASFEAWREIKKGETKIWKIEEIKLAESVGTHLYMAVMQRRVENLIRHEASHDRLTGLANRLLFSERLSLALANTQHRAEMLGVIFLDLDGFKTINDTLGHALGDLLLKIVAERLSRALPEEDMLARWGGDEFTFLINHLSSAEDVAEISNKILKSFQEPFRLEEQDFYVKASLGIALAPYDGEDAETLLKNADAAMYRAKQQGRNNYQLYTPAIGTKASERLLLETSLHKALDRDEFRMYYQPQIDLKTGRIISMEALIRWQHPELGLVAPGEFIPLAEETGLICPIGAWAIEAATRQNYQWQLAGLPPIRIAVNLSARQFHQQNLLQEIAQILTRTNLSPGYLELEITESIAMQDVSLTISLLHGFHEMGIAIALDDFGTGYSSLSSLKHFPLDQLKIDRSFIQEVATESNDAAIIEAIVTLGHGLNLVVMAEGVETLEQLEFLQSANCDAAQGYLFSKPVSVEMATELYRQSTFSYHLSS
>NC_019693.1|WP_015149204.1|3671510_3671693_-|30S-ribosomal-protein-S21
MTQVVVGENEAIESALRRFKRQVAKEGIYADMKRQRHFETPLEKRKRKEIARRRKRRYSR
>NC_019693.1|WP_015149203.1|3670946_3671414_+|SsrA-binding-protein-SmpB
MAQQSEGIKIVSDNRQARFLYEILEKYEAGIQLKGTEVKSIREGKVNIRDGYVLFRDAEAWLLNVNVSPYQTASLYFNHEPTRSRKLLLHRDQIRKLIGKVEQKGLTMVPTKMYLKRGLVKVEIALVRGKQLHDKRAAVKERDHKREIERALKQY
>NC_019693.1|WP_015149202.1|3669974_3670742_+|hypothetical-protein
MSYRNTARYLLSVLMVLAGAASPTIGAIEPSVIQEVESHQTAFFWRRQSAPDRLEGIWGITEARTPRGQSYTGSLDITAIGNTDNLYQVSWETSEGNYSGLGFYEEGRLLVGAGLDEGIYGVALYRIQNDGTLDGKWTLSNAQGEVGTEFATGGRSGQLAGSYQTRSTDPGAEDSLFTGELTITESRDIYQVTWNVDDQTYRGIGLRVDDWLVVGWGTSANLAVLDYEFKGNEATARWARTGSRELGMEKISLEN
>NC_019693.1|WP_015149201.1|3669126_3669450_-|DUF4278-domain-containing-protein
MKLSYRGSTYDYTPADVDVTEGELAGKYRGLDWKFCNQKKAPVQQATVELKYRGVALTTGEPQSANTSTPEQARRLMMDRQVKGEKRQRSMLSRLTAELKSIPVLAH
>NC_019693.1|WP_015149200.1|3668576_3668762_-|hypothetical-protein
MTKPTRFLFWLLNENPRAEEGVFYMSKLRRDQQSVKLWSVVQAHRPGLIADRLEKNIEIRL
>NC_019693.1|WP_015149199.1|3666784_3668527_-|tetratricopeptide-repeat-protein
MTQFDELQPPEGLTPPPSPPESSPPARPIAPVWSWVNHLLGAGSDYERGNRLYEQKNYAGAVAFYDKAIQKKPTMHRALLKRGTALMNLHRYEEAIAGYDGAIQVNPDDYWGWTFRGRCLFHLNRYQEALASFDQSIQINSNQYEAWYFRGRSLLELQQSKAAVTAFNKVVKLKPKLSSGWYYRGLTFLSLDRPDLALTSLEQAVALDPQNPAAWFNQGVALDRQQRYAEAVAAYDRTLQLVPENAASWFNRGVTLEKLQRYTDAVASFDRVIQFAPSNPLVWFYKGRALKHQWVEAAIGCFDKAIELHPNWPEAWMNRGIALSDAGQYEVALSSFDQATKINPNLSTAWLGRGMALYGLGRYKDAIQALSNAIQIQPNFPEAWYHRGLALEQLQRYEEALTAYEKVVQVTQEPMFRYRSWVKRSEVLEKLERYPEALDAFAKVLEVKPNDAQAWMKRGDLLSLAQRYIDAIVAYDQAIAIWPNHYDPWMKRGRVLSKIGQYPQAIAAYDTVIQMKPTHSPAWLRRGECLEKLHRYPEAARSYGVALEVDPTCTDAIDKRNRLQEKLAQDPVFPNETDLS
>NC_019693.1|WP_015149209.1|3680396_3681233_-|hypothetical-protein
MGVRKKWAGYSALMVLPWLGIQQALPATAEYPSFPEQPSVEMHWPMALEAQPTEEDGETGIAQLTETDRAGLEDLKLSIDFNQGNFVRDAAILPENSEAQSPLPMDLEAQPTQEEGEIAIEQLTEADHAGFEDLELSIDFNKGDFVRGAAILPENEAQSPNASDLAQARFPNYRYSAGFDLPTFGWVRMDGRGVDSVLGINLGLGVSYKKYFQPAVPGQFTGSWGVGTFALVLPYATIGGDYQWDNGWYAGGNIGAGLYYFDDVTPFPVGYIGVGYRW
>NC_019693.1|WP_044195169.1|3681251_3681470_-|hypothetical-protein
MGYAILILEWQIAQSFCFEFADFAVYGKLGFSGNILVLCSQESMTFNRQFPVNFTFSEHELMQKKSKLIHVY
>NC_019693.1|WP_156823850.1|3681671_3682385_-|hypothetical-protein
MAESFSGDVARELGLRAIAQSPEDTAFEPLSSDVQFEGVNPSPSLAAESENFAELLTGTTAITAPHYFMIPGQQTVPQNPATEAENNPVLAQRDNDIELGRTSRGVGNYIGAAINIGLSEDASPLGRGSFALTSKIGLAEQVSVRPSLLFGEHLMVMLPVTIDFPFAATEDTLQVDLAPYIGSGIALSTDEDNFIGFFGTVGIDRVLFDRFVANAALNVGYVEEIEVGIFVGGGYRF
>NC_019693.1|WP_015149211.1|3682659_3683595_-|hypothetical-protein
MTFFRKDEQLENLGDRILATTWEEFPQLNRNQLAMTWVVYDPPVSVNTGGALSPDAFWDHPVRGFNYRGVERIYPASVVKLFYLVAVYEWMDKEMIQTSPELERAIRDMIVDSSNDATSLVVDVLTGTTSGPELSPGPFESWKHQRNLVNRYFQSLGWPELESINVNHKTWCDGAYGRERVFLGELMENRNMLTTNATARLLHSIVGGVAVSAKATTAMMKLMKRSLEPEDLAEDPENQVTGFLGAGLDRQTRIWSKAGLTSTVRHDAAYIELPGQHPYLLVVFTEGKAHSKNEAILPFVSQQVAQAVGSL
>NC_019693.1|WP_015149212.1|3683647_3684775_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MFYKAFRTKLKLNDRQATLMAKHAGYARKVFNWGLHLWMSAYEEGLHPNINSIKKVFTNYVKPQYPWMSELSSRVYQYAFINLGDAFKRFFKGISSYPKFKKKGHHDSFTIDNCGKPFKLSGTRHNLPFVGWVSTFEALPPSLVKKVTITRQAGDWYISFFVEIPQEITPKCRERIGVDLGINTLATCSDGTKFSNPKAYKAATQKLARLQRHLSRKVKGSKNRAKCLLKVQRLHQRVANIRRDTIHKITTFLAKNHSQVVIEDLNVSGMLKNHCLAGSIADASFYEFRRQLAYKTERYGSKLIIADRFYPSSQLCSNCNHRQKMPLNQRTFECQNCGLVIDRDLNASITLEKSPGSDDYTCGRGAADSPGRSKK
>NC_019693.1|WP_015149213.1|3685313_3686039_+|C40-family-peptidase
MVLVSQLQFNLASKGSDAPQYRCRVDLNLYDSPQCETLATQASEGRLLRIALPPTEGAVGVKLCEDDYPGWLALKDLENLELAESPYQAIARDRTQIEPQIPAIIAFTHQALSVPNQYLWGGTLAPNYDCSGLMQAAFRTAQIWLPRDAYQQEAFTQPIPLDELQPGDLIFFGTPEKATHVGLYLGEGRYIHSSGKKGGRNGIGIDVLAENSDDPVSRHYYQQFRGAGRVCKSYLPQDLET
>NC_019693.1|WP_015149216.1|3687234_3688494_+|MFS-transporter
MKVFLEIEPQRRQSLLGLFAAGLLFWASLASLLPTLPLYVEHIGGTRGQIGLVMGAFALGLLPSRAWLGPLSDRRGRKIVLRLGTAVATIAPLGYLFVNSIPLLMALRAFHGISVAAFTTAYSALITDLAPDRNRGELIGYMSVVTPLGVAIGPALGGFLLEAAGYPPLFIMAFGLGLLSFLLLYFVSEPLREDLTSPVGKDSQNPQATTDSFWRLLWSPRVRIPSLVMLQIGLVFGSVATFVPLFIKETASDFNPGWFYTAAASVSFSMRLLTGRASDRYGRGLFISGGLLAYCLAMILLWTAQDSRDFLLAGAVEGLGAGTFLPMMVALVADRCAPQERGRLFAMCIGGFDLGIALAGPILGVMAEDLGYRNIFAIASVMAFVALGIFLTQSNMNLRQSLKFALGRDRDLYALQKSS
>NC_019693.1|WP_015149217.1|3688680_3689199_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MKPPFQKNSENPPNPYQLSHLDAEGQARMVDVSEKSVTHRQAIASGQVRMDRATFDQIQAGNAPKGDVLGTARLAGILGAKQTSGLIPLCHPLPLHKIDVEILPDEELPGYRILAEVRTKAETGVEMEALTAVSVAALTLYDMAKALSKAIEIESIRLERKTGGKSGDYRAD
>NC_019693.1|WP_015149218.1|3689195_3689726_-|hypothetical-protein
MIPSRLLRQHSRNRQTALAIIPLANEAATFDAYRLLQYHGISPEHLAIVGQGYSSPSRVGLLEPMQIAVDQARRFLMVFATMGFLVGSALVLAFHLGLTNPWGFNSLLLIPGVVAIAAVLGGMVGGLIGFLGEGSTVGVYHHHLRQGGYLLMIEGSQQLVTLGEQVLKPYATPKAF
>NC_019693.1|WP_015149219.1|3690037_3690289_+|hypothetical-protein
MPPRWPRQPDRSEPDYRKLDDRMNFALHVALFAASNSGLWFFRAWQSPPWQWTPWLTSAWLLLLIAHGVYIFAIANYSEESNG

Crispr_ID: NC_019693_33

• CRISPR_ID: NC_019693_33
• CRISPR_location: 3787136-3787228
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: RT

Consensus repeat of NC_019693_33

Consensus_repeat	Method
GGACCTCTCCCCAACCCTCTCCTACAAGCAGAG	CRISPRCasFinder

spacers of NC_019693_33

>33.1|3787169|27|NC_019693|CRISPRCasFinder
GGAGAATCAAAGCCCCTTATACCGTTC

CRISPR arrays and Neighbor proteins around NC_019693_33

CRISPR arrays

The CRISPR arrays of NC_019693_33

>merge|NC_019693|33|3787136-3787228|CRISPRCasFinder
GGACCTCTCCCCAACCCTCTCCTACAAGCAGAGGGAGAATCAAAGCCCCTTATACCGTTCGGACCTCTCCCCGACCCTCTCCTACAAGCAGAG

>NC_019693|33|33|3787136-3787228|CRISPRCasFinder
GGACCTCTCCCCAACCCTCTCCTACAAGCAGAG	GGAGAATCAAAGCCCCTTATACCGTTC
GGACCTCTCCCCGACCCTCTCCTACAAGCAGAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_044197211.1|3795474_3797295_-|DUF4131-domain-containing-protein	unknown	unknown	gnl|CDD|377126
NC_019693.1|WP_015149295.1|3785289_3785769_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149294.1|3782457_3785061_-|protein-kinase	unknown	unknown	gnl|CDD|238121
NC_019693.1|WP_015149289.1|3777402_3778269_-|paraslipin	unknown	unknown	gnl|CDD|259811
NC_019693.1|WP_015148065.1|3794306_3795419_-|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NC_019693.1|WP_015149300.1|3793320_3793527_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149297.1|3787377_3788352_+|quinolinate-synthase-NadA	unknown	unknown	gnl|CDD|236489
NC_019693.1|WP_015149293.1|3782030_3782240_+|hypothetical-protein	unknown	unknown	gnl|CDD|273806
NC_019693.1|WP_015149303.1|3804511_3804712_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149290.1|3778530_3780240_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|226651
NC_019693.1|WP_015149301.1|3797311_3797794_-|DUF4079-domain-containing-protein	unknown	unknown	gnl|CDD|372553
NC_019693.1|WP_015149302.1|3797981_3798878_-|glycine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl|CDD|236473
NC_019693.1|WP_015149296.1|3786119_3787052_-|TIGR04168-family-protein	unknown	unknown	gnl|CDD|275026
NC_019693.1|WP_015149292.1|3781592_3781790_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149299.1|3789404_3791186_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209
NC_019693.1|WP_083896776.1|3782246_3782447_-|hypothetical-protein	unknown	unknown	gnl|CDD|197651
NC_019693.1|WP_044195207.1|3793753_3794269_-|hypothetical-protein	unknown	unknown	gnl|CDD|225212
NC_019693.1|WP_044195203.1|3781786_3782032_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149291.1|3780641_3781475_+|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl|CDD|371375
NC_019693.1|WP_044197209.1|3788568_3789048_-|TerB-family-tellurite-resistance-protein	unknown	unknown	gnl|CDD|143581

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_015149299.1|3789404_3791186_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	1.7e-41	136.9	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_044197211.1|3795474_3797295_-|DUF4131-domain-containing-protein	gnl|CDD|377126	pfam03772, Competence, Competence protein. Members of this family are integral membrane proteins with 6 predicted transmembrane helices. Some members of this family have been shown to be essential for bacterial competence in uptake of extracellular DNA. These proteins may transport DNA across the cell membrane. These proteins contain a highly conserved motif in the amino terminal transmembrane region that has two histidines that may form a metal binding site.	1.55841e-43
NC_019693.1|WP_015149302.1|3797981_3798878_-|glycine--tRNA-ligase-subunit-alpha	gnl|CDD|236473	PRK09348, glyQ, glycyl-tRNA synthetase subunit alpha; Validated.	0
NC_019693.1|WP_015149294.1|3782457_3785061_-|protein-kinase	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	3.41441e-115
NC_019693.1|WP_015149289.1|3777402_3778269_-|paraslipin	gnl|CDD|259811	cd08829, SPFH_paraslipin, Paraslipin or slipin-2 (SLP-2, a subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model summarizes a subgroup of the stomatin-like protein family (SLPs or slipins) that is found in all three kingdoms of life. The conserved domain common to these families has also been referred to as the Band 7 domain. Individual proteins of the SPFH family may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. This subgroup of the SLPs remains largely uncharacterized. It includes human SLP-2 which is upregulated and involved in the progression and development in several types of cancer, including esophageal squamous cell carcinoma, endometrial adenocarcinoma, breast cancer, and glioma.	9.16158e-57
NC_019693.1|WP_015148065.1|3794306_3795419_-|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	8.86047e-37
NC_019693.1|WP_015149297.1|3787377_3788352_+|quinolinate-synthase-NadA	gnl|CDD|236489	PRK09375, PRK09375, quinolinate synthase NadA.	0
NC_019693.1|WP_015149299.1|3789404_3791186_-|group-II-intron-reverse-transcriptase/maturase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	3.43807e-114
NC_019693.1|WP_015149293.1|3782030_3782240_+|hypothetical-protein	gnl|CDD|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	0.000153326
NC_019693.1|WP_015149290.1|3778530_3780240_-|alpha/beta-hydrolase	gnl|CDD|226651	COG4188, COG4188, Predicted dienelactone hydrolase [General function prediction only].	2.02219e-57
NC_019693.1|WP_015149301.1|3797311_3797794_-|DUF4079-domain-containing-protein	gnl|CDD|372553	pfam13301, DUF4079, Protein of unknown function (DUF4079). This is an uncharacterized family of proteins.	3.02129e-38
NC_019693.1|WP_015149296.1|3786119_3787052_-|TIGR04168-family-protein	gnl|CDD|275026	TIGR04168, Ser/Thr_protein_phosphatase_family_protein, TIGR04168 family protein. Members of this uncharacterized protein family are restricted, in 49 of 50 genomes, to organisms with a family TIGR04167 radical SAM protein, which occasionally is a selenoprotein.	5.23063e-169
NC_019693.1|WP_083896776.1|3782246_3782447_-|hypothetical-protein	gnl|CDD|197651	smart00320, WD40, WD40 repeats. Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.	3.26365e-10
NC_019693.1|WP_044197209.1|3788568_3789048_-|TerB-family-tellurite-resistance-protein	gnl|CDD|143581	cd07177, terB_like, tellurium resistance terB-like protein. This family consists of tellurium resistance terB proteins, N-terminal domain of heat shock DnaJ-like proteins, N-terminal domain of Mo-dependent nitrogenase-like proteins, C-terminal domain of ABC transporter ATP-binding proteins, C-terminal domain of serine/threonine protein kinase, and many hypothetical bacterial proteins. The function of this family is unknown.	1.48949e-08
NC_019693.1|WP_015149291.1|3780641_3781475_+|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl|CDD|371375	pfam11103, DUF2887, Protein of unknown function (DUF2887). This bacterial family of proteins has no known function. These proteins may be distantly related to the PD(D/E)XK superfamily.	1.08505e-107
NC_019693.1|WP_044195207.1|3793753_3794269_-|hypothetical-protein	gnl|CDD|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	0.000598166

Protein sequences

>NC_019693.1|WP_015149296.1|3786119_3787052_-|TIGR04168-family-protein
MFGHNHQKSQIKIAIVGDVHEQWEPADGEALIQLGVDLALFVGDFGNESVPIVRAIAALDIPKAVTFGNHDAWFTATDWGRKTCPYNRRSEDWVQSQLDILGETHVGYGKLDFPEFGLTVVGARPFSWGGSEWKYADFYSDRCDVSSFVESTDRIMAAVKRASFDTIIFLGHNGPKGLGDRPEDPCGKDWKPLGGDFGDPDFADAIAQTRKMGKTIPLVTFGHMHHRLRHTKTELRKSLHTTSDGTVYLNAARVPRIVPTKTGQLRNFSLVELEGNTVTRASLVWVDQNFAVASEEVLYQQHPESVATLA
>NC_019693.1|WP_015149295.1|3785289_3785769_-|hypothetical-protein
MTDKRIRAYIKLIQKLLDCPEGDELKILRKHRHLIDVQFVYVLNQAAEKAEEEGEEDTASFLRTLSEQLELAFAEIVKRTHPAVSERNQAYLQIIEEILKCDTGEEVAHILHQNSERVDRGFVKTLAQVAQLMVENGQPDSAAVLIDLATVISSAIEEG
>NC_019693.1|WP_015149294.1|3782457_3785061_-|protein-kinase
MRCLNCHAEGIPSTNQYCPKCGAHLPALQQNLLPEQTRLKADTYEIEYALGRGGFGITYRAHHIGLEQPVAIKEYYPQELAHRHSNNGGLTVPQNKTEMYQRWLTRFLREGRILAKLNHPSLVRVQDLFEERNTAYLVMELLSGKTLGQELDEQPGKNLDPQRVREIITSLVSALAATHQAGVYHLDLKPDNILLTPEGRIVLIDFGAAKQESATIGPTRSTRAFTPDYAPPELIGNQAIGPESDIFELGMLLHQMLTGTLPPPALSRLIGEPWEPQLQEPWQSLVASALPLQKNQRPNNISEWWKTAASQVNSYPNLPSTKPSVPKPQVSPPILKPQPTSASAPGKSVIDLRGYFILPELQAQGMVRRFGRGTIKNVLLLNQELAIVCAGGGSALFNLSSGEVLWEIDCPANSGAVSLDRKLLALGGQQAIYLWDVTTGQFLRQIQGHPNRVDSVAFSPDGKFLASGSLDKTVRLWDAATGRELCQLCEHTKSVVSVAFSPDGKFLASGSWDKTVRLWDPSTGRELHQLYGHTDLVKSVGFSSDGKFLASGSLDKTVRLWDAATGRELRQLCGHTSSVKSVGFSPDGKVLASGSKDKTVRLWDAATGRELRQLCGHPDPVDSVAFSPDGKFLASGSLDKTVRLWDAATGRELRQLCEYTSSVKSVAFSPDSKVLASGSKDKTVRLWDTVTGRELRQLCGHTSSVDSVAFSSDGKFLASGSLDKTVWLWDAATGRGLRQLCGHTYSVISVAFSPDGKFLASGSWDNTVRLWDAATGRELRQLCGHTLSLDSVAFSPDGQVLAYGGWDNTVRLWDAATGRELRQLCGYPDSAKSMAFSPDGQVLASGGLDNTVRLWDTATGKELRIAN
>NC_019693.1|WP_083896776.1|3782246_3782447_-|hypothetical-protein
MLIVIVGWASRPSHTLLEVIKFSFLRTFLAHTGSVDSLAFSPDRKYLASAGGDGVVRLWDVADLQS
>NC_019693.1|WP_015149293.1|3782030_3782240_+|hypothetical-protein
MLELGSWKDNRFYQETLAEGIEKGEMRAKIKAVKPLMRHGLSLEAIAESLELPLDLVREAAEDSNSQED
>NC_019693.1|WP_044195203.1|3781786_3782032_-|hypothetical-protein
MGDISFQAKIWDKTPSIHGIRTYTLPLNVEAIRESPLHLGGVLKICGSPVNEAGMITEGSWIRVGRFVYVILLISPGIEWV
>NC_019693.1|WP_015149292.1|3781592_3781790_+|hypothetical-protein
MFELGSWKDNRSYQECFAEGQMEARIQAVKPLMRHGLSLEAIAESLELPLDLVREAAEDSKSQED
>NC_019693.1|WP_015149291.1|3780641_3781475_+|Rpn-family-recombination-promoting-nuclease/putative-transposase
MRTDTIFYTIFQKYPTIFFELLHRPIQEASAYQFTSIEVKQLAFRIDGVFMPTEEEPNRPFYLTEVQFQPDDELYYRIFAELFIYLRQYKPANPWQVVIIYPNRRIEPKDQVQFQELLNCDRVTRIYLDELEPEGESTLGLGVVKLIIEPETAAVETAKRLIAQAAIELPNPNHQRDLIELIETIIIYKLTTKSPEEIAAMLELKSWKDNRFYQESVAEGIEEGLKRGKIEGKMEAKIEAVQPLIRQGLSLEAIAECLQLPLDLVREAAEDSNSQED
>NC_019693.1|WP_015149290.1|3778530_3780240_-|alpha/beta-hydrolase
MKQTQIIGWGSSGKLSGNLGFNRRFRRWHHRAIAPLIAAMLAVASGANVATLAAESLTFRLGPWQGSIALDDLEEYARTGELPGNLAPLGPFLPDGLQEVLAQRVEIDPDIGDRALDRLITSPQGNRFVRAIFLLVPDSTIDQIKDAIKLVATQGNGLSLLGILKALPGDNIVFDATSAIGVASRLNLPYLEGQILRSRLESDLELETEPFYSSFDPALPGSQTVSQQTLTFRDRQRNREITTEIYSGNNPQGPLAVISHGFASNRFLLEYLAQHLASHGITVVSIEHPDINEESVANLPLTLDPTNLIPASVFLDLPKDVSFILDELAEINRQPGSLAGQFNTEQTLVIGHSFGGYASLALAGGELNLNELREFCEGGRKLGRSPADLVQCAATELPGNRITLRDRRIKQAVAINPTVGNLFGDKGLGKIDIPILLVASSDDSWTPAVNHQLRPFTQLREPKYLLTAIGGTHFSTTDPSRPSLLERETALPDDPSREQTENLRLLLRGVTLAFVKQQTPEARTYAPFLSAAYAQSLGTEETALRLNETLPTRLARWLATSEAALGRLD
>NC_019693.1|WP_015149289.1|3777402_3778269_-|paraslipin
MNTFFAFIVPLIFGILGYTVSAVKVINEGNEALVERLGRFNRKLSPGPNLVFPYVESIVVEDTTREQVLDVPPQNAITKDNVAIKLDAVVYWKIMDLQKAYYEINNINLAIKNLVLTTLRSTIGHMELEQTFYSTDEINRRVLKSLDEATFSWGIKVLRVEVQDLDPPKTVLESMEMQRASEIRKRATIVDAEATAESVQLILDLLQPQMTTTEVMKYLLAKRYVDANEKLSESPNSKVIFMDPKALNDTLSELIYMPEIGQHLNNPNNPPPGGNPPPTPPGNGSNPT
>NC_019693.1|WP_015149297.1|3787377_3788352_+|quinolinate-synthase-NadA
MFTATLSPPNSAQTSAIPDDLFAAIESLKQELNAVILAHYYQEPDIQDIADYIGDSLELSRKAANTNADVIVFAGVHFMAETAKILNPNKLVLLPDLDAGCSLADSCPPDAFGEFKAAHPDHIVISYINCSAAIKAMSDIICTSSNAVKLVRQIPENQPIIFAPDRNLGRYVMEQTGRDMVLWQGSCMVHETFSEKKMVQLKIQHPEAEIIAHPECEPPVLRHANYVGSTSALLNYAQNSDSSVFIVATEPGIIHQMQKQAQDKQFIPAPPMNSCACNECPHMRLNTLEKLYLAMKNRAPEITLPEETRVAALRPIQRMLEMSA
>NC_019693.1|WP_044197209.1|3788568_3789048_-|TerB-family-tellurite-resistance-protein
MQPPPPPSITPRQMNLLRVVTAMAWADGELAAEEVDIMLDRFSRLFSVSPQQQDKLKEELRDYMMQNIPLEELIPKLTTQPERELVLQLGYEVIASSARTPDEPNINAEEAEAYQKLVSLLNLPADVVPRIEAEAEKSLQNEEGIIEKLASQLQAFLNQ
>NC_019693.1|WP_015149299.1|3789404_3791186_-|group-II-intron-reverse-transcriptase/maturase
MTKSRGRKGFGKRGPSETTNVWKAINWAKVQRYVFKLQKRIFQAAKSGQDAKARRWQRLLVKSYYARLLAVRRVTQDNQGKKTAGIDGVVIISPNQRLGLAEEIKGRLKAKPLRRVWIPKPGRDEKRPIGIPTIRDRARQALVKAALEPEWESKFEGTSYGFRPGRSAHDAIVRIYAAIKMNSYYVLDADIAKCFDLINPEHLLSKIHCPSRLKRDLKQWLKAGVLDNGVFEETYAGTAQGGVISPLLANIALDGMARLIETKFPKKNSVVQATLIRYADDFVVISPRLEVIEQCQTAISEWLKPIGLEIKPFKTRVCHTLKPIQYDGKTEEPGFNFLGFNIRQYPVGKYKSGKTGGGASRLIGHKTHIKPSKDAVKAHIEAIKGVIKQHKTAPQSALISRLNPIIQGWSNYYSGAVSGKTFTKLDYTVWQILRAWTVSRCGKANHPKLRNYFRPGTVKLVNGKERHESWMFQTPDGLRLFKHNWTPIVRHTLVRPDATPYDGNWTYWATRKGQAIETPTRVAKLLKKQKGRCTWCGQYFTPSDLVEVDHIQPRSQGGKDEYKNLQLLHRHCHDEKTALDAAKAVSLTKEHSN
>NC_019693.1|WP_015149300.1|3793320_3793527_-|hypothetical-protein
MERPIAISEDLANRLERYLQQHPHESVSGLLEEILQQKENNSSAPPKFLRIQPAATDSGYRHTSIAHD
>NC_019693.1|WP_044195207.1|3793753_3794269_-|hypothetical-protein
MRVFSSPETGPHQTGDRPLLTNLSHRKGSYHPLPIGQTLAVGTTGIQVVSLKPPVAQFQIHNQVWLFLGDLNPSEQSRLVTAGSLLAGENGESPLRVLWWSGEQLAPYLVEALQPSVAIASSDAIDPQTERLLRQRNTQIYAIGREGAIQWNSRDGFRSTLDPRENENLFL
>NC_019693.1|WP_015148065.1|3794306_3795419_-|IS630-family-transposase
MPAAKCLTPEQLKKLQKAMKEEPNGEIRERILMLLLLNDGKTQAQIAKFIGVSINTVCHWCIHGDPDNLESLRDKRMEGNNKKATEEYVNLLLETLSKEPTELGYEFGRWTAHRLATYLHEITGIQLSGSQIRRILAKKKYVYIWGKYSLESKRDEEERKEFKKKLSEYLRIEKETPELLQVWFWDESGFSLRVIRRKNWCKKGKRKQLRGDRRNGRVNVMGGIRYSDKKRFVEFLKTSNSESFYNVLKVFYQELIQEWCDSGKSAHDFSVKGPKIIIILDNASFHKKAEFIQKIGENMPNIQLEFLPKYSPDYNLIELVWHSAKEYVAHRLFTSIEDLEALLHKLLNEGELIIRWSRKLKNKGNAVIPV
>NC_019693.1|WP_044197211.1|3795474_3797295_-|DUF4131-domain-containing-protein
MTSAPLVVLCLAYILGLLCARFIWGGVVVLTLTGAIAAILLLKVPFPKRLEVLKAGLQPRIWLIAGAIGFLATLYLPLRQPQIGVNDVSRFVAASDAPSQQQLVNVFGKVASEPRLTRSNRIQFWFEPNQVIEIVGTSGRGGSDTAKTQTVTGKLYVTVPLLQGTGLYPGQRVEVTGRLYLPQPAANPGGFDFQAYLAREGTFAGLAGRQVNFPSSAGSPPTWGMWQLRRRILRAQVRGLGVPEGPVLSAMVLGRRAVDLPHDIRERFMQVGLAHVLAASGFHVAVILGLVRAVTRRFSEKAQFGYGAAVLIIYVFVTGGSPSVLRAALMGFAALLAPLMQRQVNALGSLLLAATFLLIWNPLWIWDLGFQMSFLATLGLLVSTPAVLKRLDWLPPAIASLIAVPIAVSVWVLPLQLYTFGVLAPYSIKLNILLSLPLAGITLGGFISAIAAAIWPLAGTAVAWLLYYPLKLTIAIVEFVSQLPGNSIATGTLSIVQLVILYGIVVSVWLIPWLHQKRRWVLGFLFAVGLVVVPVLYARTTVFQITALATRGDPVVVVQDRGKAIVINSGDEATARYAVLPFLRQQGVNQIDWAIATTPVNYRSGW
>NC_019693.1|WP_015149301.1|3797311_3797794_-|DUF4079-domain-containing-protein
MIDLSEALEPIASQFRSLGLPEPIVHWGHPLMMGIVIFVMGSYVGWSGWRGRVPADKDAAIKGRSDHRKLAPWMFLFMALGYTGGVLSLVMQRQPILESPHFWTGSILLVLLALNGTLSLGFQGDRLTLRAAHAYIGTVALGLMLLHALLGLKLGLSISI
>NC_019693.1|WP_015149302.1|3797981_3798878_-|glycine--tRNA-ligase-subunit-alpha
MNFQSVIATLNQFWADRGCLIAQPYDIEKGAGTMNPHTFLRAIGPEPWSVAYVEPCRRPTDGRYGENPNRYQHYYQYQVIIKPSPNNIQDLYLDSLRALGIRPEDRDIRFVEDNWESPTLGAWGVGWEVWLDGMEITQFTYFQQCGGIDCRPVSIEITYGLERLTMYLQEKDAFTKINWTDEVTYGDVHLQGEVEQCVYNFEASNPDLLFKLFALYEEEAEQLTARGLVAPTLDYVLKCSHTFNLLDARGVISVTERTRYIGRIRNLARRVAHLYLEQREKLGFPLLKGDSSDNASAA
>NC_019693.1|WP_015149303.1|3804511_3804712_+|hypothetical-protein
MSENLENLTNSELKSYIKAHRNDESACHAALKIMMSRRSENTAKYAYDITDEEMEAIFQEKLQSKS

Crispr_ID: NC_019693_34

• CRISPR_ID: NC_019693_34
• CRISPR_location: 3928765-3928861
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_34

Consensus_repeat	Method
TAAATTTAATGACGAAAAATCAGGGTTTCTTG	CRISPRCasFinder

spacers of NC_019693_34

>34.1|3928797|33|NC_019693|CRISPRCasFinder
GACAGGCGATCACTCTCGCGGCCCTACAAGAGG

CRISPR arrays and Neighbor proteins around NC_019693_34

CRISPR arrays

The CRISPR arrays of NC_019693_34

>merge|NC_019693|34|3928765-3928861|CRISPRCasFinder
TAAATTTAATGACGAAAAATCAGGGTTTCTTGGACAGGCGATCACTCTCGCGGCCCTACAAGAGGTAAATTTAATGACGAAAAATCAGGGTTTCTTG

>NC_019693|34|34|3928765-3928861|CRISPRCasFinder
TAAATTTAATGACGAAAAATCAGGGTTTCTTG	GACAGGCGATCACTCTCGCGGCCCTACAAGAGG
TAAATTTAATGACGAAAAATCAGGGTTTCTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015149411.1|3937977_3939927_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|227328
NC_019693.1|WP_015149413.1|3942478_3943441_-|DUF1338-domain-containing-protein	unknown	unknown	gnl|CDD|319960
NC_019693.1|WP_015149409.1|3933899_3936554_-|colicin-transporter	unknown	unknown	gnl|CDD|240439
NC_019693.1|WP_083896863.1|3930484_3930994_-|cold-shock-domain-containing-protein	unknown	unknown	gnl|CDD|239905
NC_019693.1|WP_015149403.1|3924096_3925023_+|ribokinase	unknown	unknown	gnl|CDD|238579
NC_019693.1|WP_015149400.1|3920971_3922753_+|SWIM-zinc-finger-domain-containing-protein	unknown	unknown	gnl|CDD|227059
NC_019693.1|WP_015149412.1|3940168_3941902_+|urease-subunit-alpha	unknown	unknown	gnl|CDD|237305
NC_019693.1|WP_015149408.1|3933412_3933667_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044195236.1|3918705_3919935_-|PQQ-dependent-sugar-dehydrogenase	unknown	unknown	gnl|CDD|369642
NC_019693.1|WP_015149406.1|3929166_3930045_-|DUF1361-domain-containing-protein	unknown	unknown	gnl|CDD|369208
NC_019693.1|WP_052315745.1|3936894_3937947_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149402.1|3923476_3923959_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149405.1|3926116_3928576_+|phosphoenolpyruvate-synthase	unknown	unknown	gnl|CDD|273612
NC_019693.1|WP_156824064.1|3925304_3925982_-|ComF-family-protein	unknown	unknown	gnl|CDD|223970
NC_019693.1|WP_015149407.1|3932999_3933416_-|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350263
NC_019693.1|WP_015149401.1|3922912_3923407_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149397.1|3916459_3917248_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149398.1|3917900_3918668_-|superoxide-dismutase	unknown	unknown	gnl|CDD|223678
NC_019693.1|WP_052315744.1|3931363_3932479_-|hypothetical-protein	unknown	unknown	gnl|CDD|378452
NC_019693.1|WP_156823862.1|3920493_3920805_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015149411.1|3937977_3939927_+|CHAT-domain-containing-protein	gnl|CDD|227328	COG4995, COG4995, Uncharacterized protein conserved in bacteria [Function unknown].	7.52884e-83
NC_019693.1|WP_015149409.1|3933899_3936554_-|colicin-transporter	gnl|CDD|240439	PTZ00491, PTZ00491, major vault protein; Provisional.	0
NC_019693.1|WP_015149398.1|3917900_3918668_-|superoxide-dismutase	gnl|CDD|223678	COG0605, SodA, Superoxide dismutase [Inorganic ion transport and metabolism].	1.01237e-108
NC_019693.1|WP_015149403.1|3924096_3925023_+|ribokinase	gnl|CDD|238579	cd01174, ribokinase, Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides and histidine, and for entry into the pentose phosphate pathway. Ribokinase is dimeric in solution.	1.07556e-134
NC_019693.1|WP_083896863.1|3930484_3930994_-|cold-shock-domain-containing-protein	gnl|CDD|239905	cd04458, CSP_CDS, Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. CSP expression is up-regulated by an abrupt drop in growth temperature. CSP's are also expressed under normal condition at lower level. The function of cold-shock proteins is not fully understood. They preferentially bind poly-pyrimidine region of single-stranded RNA and DNA. CSP's are thought to bind mRNA and regulate ribosomal translation, mRNA degradation, and the rate of transcription termination. The human Y-box protein, which contains a CSD, regulates transcription and translation of genes that contain the Y-box sequence in their promoters. This specific ssDNA-binding properties of CSD are required for the binding of Y-box protein to the promoter's Y-box sequence, thereby regulating transcription.	3.112e-14
NC_019693.1|WP_015149412.1|3940168_3941902_+|urease-subunit-alpha	gnl|CDD|237305	PRK13207, ureC, urease subunit alpha; Reviewed.	0
NC_019693.1|WP_044195236.1|3918705_3919935_-|PQQ-dependent-sugar-dehydrogenase	gnl|CDD|369642	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase. Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.	4.86401e-110
NC_019693.1|WP_015149406.1|3929166_3930045_-|DUF1361-domain-containing-protein	gnl|CDD|369208	pfam07099, DUF1361, Protein of unknown function (DUF1361). This family consists of several hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown although some members are annotated as being putative integral membrane proteins.	5.12951e-46
NC_019693.1|WP_015149405.1|3926116_3928576_+|phosphoenolpyruvate-synthase	gnl|CDD|273612	TIGR01418, Phosphoenolpyruvate_synthase, phosphoenolpyruvate synthase. Also called pyruvate,water dikinase and PEP synthase. The member from Methanococcus jannaschii contains a large intein. This enzyme generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process. The enzyme shows extensive homology to other enzymes that use PEP as substrate or product. This enzyme may provide PEP for gluconeogenesis, for PTS-type carbohydrate transport systems, or for other processes. [Energy metabolism, Glycolysis/gluconeogenesis].	4.82615e-113
NC_019693.1|WP_156824064.1|3925304_3925982_-|ComF-family-protein	gnl|CDD|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	5.66459e-39
NC_019693.1|WP_015149407.1|3932999_3933416_-|PIN-domain-containing-protein	gnl|CDD|350263	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins. Mycobacterium tuberculosis VapC26 cleaves 23S rRNA in the Sarcin-Ricin Loop, it is inhibited by the cognate VapB26 antitoxin. This subfamily belongs to the VapC (virulence-associated protein C)-like nuclease family of the PIN domain-like superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	5.57271e-15
NC_019693.1|WP_015149400.1|3920971_3922753_+|SWIM-zinc-finger-domain-containing-protein	gnl|CDD|227059	COG4715, COG4715, Uncharacterized conserved protein [Function unknown].	3.59328e-87
NC_019693.1|WP_015149413.1|3942478_3943441_-|DUF1338-domain-containing-protein	gnl|CDD|319960	cd16350, VOC_like, uncharacterized subfamily of the vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	4.60024e-101
NC_019693.1|WP_052315744.1|3931363_3932479_-|hypothetical-protein	gnl|CDD|378452	pfam10592, AIPR, AIPR protein. This family of proteins was identified in as an abortive infection phage resistance protein often found in restriction modification system operons.	2.18669e-22

Protein sequences

>NC_019693.1|WP_015149405.1|3926116_3928576_+|phosphoenolpyruvate-synthase
MDHLYWLDQIQPSQRYLVGDNPFYLSQMAQQGYPVLPGFVLAAPALREFLETYPWEEPLFAELLSSSVHLNVDDTRQLKAIAQHIREQMMAAELPQQWINDLAIAAEKLSSPGLILSLSVTLPQNTPSPVKFSGLVESYVCLCDPEEIALGVLQTWAELFRARSLLYWQRSQIELRALNLAVLVQPLHSAITSGTLTYTPAHCEIKATWGLPLSIKLGQAIPDWYQIELEKGNAIAQSLGNKHLGYDLRWNSTPPDELTAETSLLSPYSCLQPYLVSDEQQQEFSLKPRELETLGAIARNLGSHLNRQFSLEWTLVKATEQSPEQIYITGVEVGNPLPSLEMTAPVDPPSSPKSVPVTAIEGEEMPQIILGTGAAKGVAVGLVYCIPSPTEVLEHIPPGRILIAKEIAPHWLHIVRQAAAVVTESGGMTSHAAILAREFGIPAVVGAAGVMQAIATATEICVNGDTGEIFILPAGTVPPSPVRSPQPVATAVSIPEPMPSPDSNPLSSPFPTATQLLVNLSHPSSLDRIADAYLDGVGLLRSEMMALEIFQSEDPYQWCDHHKNQEFIHRISDPLKRVAEFFFPRPVFYRSLDLRGYDLPGMRSPGQTSINSNRSAQTLGVHGAFSYLLDPTLFDLELETLAKLQQEGLTNLRLIIPFVRTVEEFIFCRSRVQQFKLDRVRDFQLWIMAEVPSALFLIPDYVQAGVQGISIGTNDLTQLLLAADRENQQMSQVFDPRHPVVMRAIHQLIQQAKAAGIPCAICGGAPTRYPETIDTLVRWGIDGISVEPEAIVRTHQAIARSEQRILLETARRDSEDCPF
>NC_019693.1|WP_156824064.1|3925304_3925982_-|ComF-family-protein
MGNWPAMVKGWVNLFLKPTCPLCDRPGKPFLCPNCDRQLQRQKFSVKQRLLQETPPVLIWGRYGGVMKRAIAVMKYQNCPELAQPLGYFLAETWLQSPLAKAQGLTVVPIPMYPDKQRKRGFNQAELLAKSFCELTGYPLEPRGLERVRDTEALNQLSPEQRRQTLANSMRVGAGFCRSKPKQGVILLDDIYTTGSTCQEAIRTLSKQGISVYGIAAIATTQPVD
>NC_019693.1|WP_015149403.1|3924096_3925023_+|ribokinase
MNIVVFGSINLDLVTRTHRLPKPGETLAGISFFTASGGKGANQAVAAAKLGMTTWMIGRVGGDSFGQELLESLQQSGVKCDRILIDENTTSGIATIAVEDTGENTIVIVPGANDRVNESDCDRLTDLLPDAAALLLQLEIPLSAVLAAAKKAQDAGVPVILDPAPARELPPELYSLIDIITPNETELSLLTGLAVRDVETAREAITELQKRGVKTAIAKLGGKGVLCARGEEQFFVPAFEVEAVDTVAAGDAFNGALAVAIAQGLSLPEAVRWGAAAGALAVTKPGAQSALPSRLTFEEFLREGKIKT
>NC_019693.1|WP_015149402.1|3923476_3923959_+|hypothetical-protein
MLTCQRFTIKTGLKPYQVREKLMGIVEPTCRIGETSSPPLYRGKINKDSFQISKIIYHRRSDRYRESFLPVLVGQIREHDSGSQIDIQVKMPPLFLVGIGIWLMTMGREVWVSLMMLQNGFSPTFAGFIGIFLLGLAIQIIIFLSIAHNSKKFLINFLKD
>NC_019693.1|WP_015149401.1|3922912_3923407_+|hypothetical-protein
MFPSQRFTITTYLSPDAVQKRLMEVVEPPLTGIQFQRKRSDKLYRGQIGEHSFKIARIIYYRNSFLPQIEGRIKAHGRGSQIDIEMKLHTVVIIFMGVWLSIIGQVALLSLFALFQEDFEPAFLMPVGMVIFGLALPWIGFLPQAKGSKQFLMELFQAQEENSI
>NC_019693.1|WP_015149400.1|3920971_3922753_+|SWIM-zinc-finger-domain-containing-protein
MSKTPDLTDRLLRQKSAPELFRKGQSYYELGNVTAVTQRGNLLNAEVIGNAVQPYRVRVGFDEGGVNSATCSCAYDDEEWCEHIVATLFVVMRQPETLQERPTLEELLDQLNQLQIQELVKELVKQNPELIDEVDCYITLKTEIRSTIQSVNNQRPSPINPDPFRQQARDILYEGMRYFENLDGEDDPVTEELLDLIDNVQGLIEIGETYNALIVLEAIASACAADWDRVEQYGIDSDDIITALDEAIAEAILSDSLSSSEVKQWRSRLEILQDKWSTEFALSLESLAQGWDNPDLVAALNGTLAEPEIKEESLANYSPDLVLIRLRILDRQERYEEYLNLAKVKGQMKQYLTMLGSLGRTAEAMEAAATQMKTMEEALSLGQTLRSNGEVSKALKVGEMGLKLPGNCQYELASWTADLATGLGKTEVELEARQSAFCAQPTSPDYFRIKELTGENWSKIQPDLLKALRQHTSWGTIEVKVDIFLSEGLIDEAIACVTDLSDYHSALLHRVMEAAIPKRPDWVIENAQPRAESILDRKKSESYNHAINWLKKVRAAYIQKEQLEEWRTYRQELLKTHARKHKFRGMLEDMRLY
>NC_019693.1|WP_156823862.1|3920493_3920805_-|hypothetical-protein
MIQFVEGIRGDRNIPSRPTATGIRGNSPLIPQANIPRFNKNIRLVPLDRFCCDRLMVKVLPLICTLVGFGRVLSGITCTCRECGPRPPSRNNKALTQLKIDPE
>NC_019693.1|WP_044195236.1|3918705_3919935_-|PQQ-dependent-sugar-dehydrogenase
MKLTHSLTFIPIVSLIGVVSCTAPTGALLENNTTGQGNRPQEQAQGVPTPGGEAACILVENSFGPQGQVNVRVEEVVNGLDVPWGIGFLPNGDMLVTERPGQVRLVQNGQLRPEAVANITVTARGEGGLLGIAMHPDFASNRFFYIYYTADTNGSSVNRVERWQLAPDGLSATRDRMILDDIPVAQFHNGGRIRFGPDGMLYIGTGDAREPDLSQDVSSLAGKILRVTPEGDVPSDNPFPGNPVYILGIRNTQGFDWVNETTLQVTDHGPSGELGRRGHDKVSVAQAGDNLGWPTIYRCESGEGLVTPSIVWRDALPPGGAAIYTGTAIPEWQGNLIIATLRSEHLQRVVFDPQSPQQVQQHEVYLQGEYGRLREAIVGPDGELYITTSNCDGRGGCPPDGDKILRVTR
>NC_019693.1|WP_015149398.1|3917900_3918668_-|superoxide-dismutase
MRNQKKWRFGSILAGFMALFLLIACQGMGQTNLSQTPTTTTPTGNELSASPAELPPLPYPYNALEPHIDARTMELHHDKHHASYVSNLNEALENNANLRNQSVESLIRNLNQVPEDIRTTIRNNGGGHVNHSMFWAIMSPNGGGEPTGAIAQAITENFGSFETFKEQFNQAGSSQFGSGWVWLVRNAQGQLEITSTPNQDSPLIDGQYPIMGNDVWEHAYYLNYQNQRGEYLNNWWNVVNWEEVNRRFETASQAS
>NC_019693.1|WP_015149397.1|3916459_3917248_-|hypothetical-protein
MEIYVKSRGFSQEEGYCWLPETPSILTLNRVADCIQTESPSLVLGRYSGRLLLLITGLEARGRTDFRDRAIRNSIAWVAEDSAANEQQLRALAIRALRTFLEEKQDGLDAEIDQAIPLGGPDGFTVNWELLKGLSSSATLSSQPQKSDREREEHSTDKLAKNCDRTKETLATQLEYYGLPQREGPLVVVTGIKSKDSLIQARVWRGLSKSLEEEDWTPVRERQDALNSSEEPFQSGKKLNETATLVAGIVAIGMLFLGLLWF
>NC_019693.1|WP_015149406.1|3929166_3930045_-|DUF1361-domain-containing-protein
MTAQLMDWMTVAWGAMRGNHVFMVWNTFLAVVPLALSFWLFHKPRSQWLRWGVFLILGATFLPSAHRVFRTGIFLLQRISADYLIWILILTLILMSSEIWQLRRSQNSSTVSRSLLWWVGFVAFITFLPNAPYVLTDVIHLITDIRAGYSVWIITLALIPQYLIFMIVGFQSYVLSLIYLTWYMERSGLRRWTGLAELVIHGLTAIGIYLGRFQRFNTWDIVTDPDILVRSVMNDLIGRRPVLVMIVTFVVITVLYWLFKQLTLALMHRNSQPKSAWSPVAPVESPAADSEG
>NC_019693.1|WP_083896863.1|3930484_3930994_-|cold-shock-domain-containing-protein
MLVETSQIPYLNSKKIEKYCDSLRGVLWDDDQALETFKKATLLIDKVLAKVTYSQFEATRRKAFTTDLITQLNEDFVTTPAESPALKRPQSAFVAAQVEREQGTVTKFSNIRGFGFIRGKHEQDIFVHFRDIRGDEQRLNAGDVVEFVLLINEKGLNAKAVEIVSRSSS
>NC_019693.1|WP_052315744.1|3931363_3932479_-|hypothetical-protein
MDQILKSYVKNFVDESSLDHLDEATAFEYFVNHTVLSKIHPDPFDVETTIIGGSHDNALDGIAVLVNDHIVTSQEEIDFFRKTLRRFEVKFVFIQSKTSPKFDSGDLGNFLFGVRSFFEEQPAIPMNPQLTNLRTLKDYVYRFSIDMDMGKAPVCEMYYVTTGTWLGDATLEGRIQVEKTAIEGTKLFSQVRFVPVDNEYIKRLYLELRRKVTKEINFEKHTAMPTIGEVHQAYIGILPALEYLKLITDAEGNLIRSLFYDNVRDFQGHNLVNQEIEVTIQDQEQSDRFALLNNGITVVAKNVQQVGSRFSIQDYQVVNGCQTSHVIFLNKDALTDKLFVPLKLIVTNNTEVTNQIIRATNRQTQVYVEAF
>NC_019693.1|WP_015149407.1|3932999_3933416_-|PIN-domain-containing-protein
MILCDTGILITIVDRRQPKHYAYRQAISRYACPLLTTWACLTEAMYLTHRLGGWTMQHQLGKLIVQGGLITYSIDTAQQMTRLLALMEQYRDRPMDFADATLVLVAEETGQRQILTLDSDFLFYRIHNRDSFEIISVD
>NC_019693.1|WP_015149408.1|3933412_3933667_-|hypothetical-protein
MSNPPPIRQQLDRELDRLPPESLTQILAFARSLQPQTDYTTLWENWFAEVDTLPLDSQPPNVETAPLNYTDYLVEKYRDQGLNL
>NC_019693.1|WP_015149409.1|3933899_3936554_-|colicin-transporter
MSKPDKLSENPTLESDLASGVIRLKPQEFIHVLDNNTGITRLEVGPQTITLRDGERLILKPQPAIVVPPRHYCIVANPVMRDENGAPSTDPRGQIKLRYGDREIRLSQEPFPLYPGEELAESVTQLQVVETNQALRLRALRDFSETRTIPGETPQTQMIERVAGDEWLFEGPGTYIPRVEVAIVKTVQATIIKTNQALRLFARQNCIDRQGIRRRAGEEWLVREEGAYLPGIDEEILGLIDAYVLTERKALHLKAKRSFTDIFGRQRKAGDEWLVTLEDAEIHIPDVYEQVVGEVQVTTLNDREWCIVVDPIDRNGKPQFGMWEVRQGRITFFLHPGESLHNGIQKVYVLGEQEALLLRADEAFTEGTPENPIHHQPGDLWMIHGPRDYIPPVQVKVIETRKAIPLDKNEGIYVRDIQTGELKLVSGPQAYLLAPHEEPWEKELPPVVEDLLQRKSDPLGDRGEYSGSREETQGRTQNPRKQRDKTRAVVFHVPQNAVVQIHDYKERTARNVFGPDLVMLGPDEAFTVLSLSGDKPKRPNAIKSLALLLGPDFMTDIFTVETSDHARLQLQLSYNWYFEVDKTNEEQTEKLFQVPDFVGAACKAIASRVRGAVAGVQFDEFHRNSARIIRQAVFGVDDEGHIREDFRFRSNNLVITNIDIQSVEPVDEETLKSLQKSVQIAIQITTDAQEAAARHDAERIAQQAKARLERQAIVDKSAAEAERRNLLELEAENAAISSTGQATAEARAKAEAAQIQGQLQVNLATQEAEANRIRAEVELVQLRSRQEAEFAHQQALTNLEIEKAQRMAEITSTEFAQKVAALGPETLRAMAQAGPEMQARLLAGLGLQSVLITDGKSPINLFNTANGLIGGVPSNLGGNGREET
>NC_019693.1|WP_052315745.1|3936894_3937947_+|hypothetical-protein
MIIQLLLLGILLPLDVAQAGELEPWQAEGFGDKLEFSAHAADLEPVFFQPIQGDRTVVLLTEPNAGEGTVHPQSEIAQGDPATAPEGMTPRQGTPLHRGIPGEQPFIPQRIPFRPRTDVTTTQSKPYAASPAITVMTPSGYGAGWGSAGFGLGLQERTRFTDSSDGVAGFGIGFGNPRENIGLTVGVTVTDLWGDAFEDGSVSLKLHRQLPNDFGIAAGVQGALTWGETDGGTSGYGVVTKRFILDEPENLWSQVYLTLGVGGGQYRSESDIEAGEGTVGLFGSVALRVAPPVSAIAEWTGQDLTLGLSVVPFRNIPLVISPAITDITGSAGDGTRFILGIGYGFTFDRF
>NC_019693.1|WP_015149411.1|3937977_3939927_+|CHAT-domain-containing-protein
MKRFKGWTKLLLAMTLVAIAADPAITQTANQSDITGPIIDTPTIVPAGTIEPESTVTPTNTNPDTPDTTPDTPDTTTDTPDTTTDTPDTTTDTPDTTTDLPPGDTSVTPIDSPEEQVITTPVQPVEPINIQSPETTAPVVIPDNPEVPIEAEIPPTVGENNPEPDPTTESANPIEAQILEGAASRTTETEPFSNLSEQEIDRPGYESQLAVADIRVAVQMLEEYQAMQFSNYLEVDLFGETATPDEIAQALYDLWQATGNKSAFIYVSALANQLELVMIFPQNFRVAGGSSELVASTNLAQGLIERTTDIAIRETVPNVSREQLLEQVQNWRSELTNPRRRTSQSYLPVAQSLYQSLIAPMEAQLEANGIETLVFSMDSGLRTLPLVALHDGEQFLLEKYAIALVPSFGLTDVTYSDIRNREVLGMGSAIFDDLNPLPAVPTELQNIVRNFEIGNVFLNEQFTAENFRKTNQENRYGIIHLATHAEFQGGSLANSYIKFFDSRVGLNQIRDLATELGWNTAQNPPIELLTLSACRTAVGDTEAELGFAGLAVLSGAKASLASFWYVSDAGTLGLMSEFYSQLAEKPLKAEALRQTQLALLRGEVRIENGMLLLSNGTTVPLPPELAVQGNLTLSHPYFWSAFTMIGNWN
>NC_019693.1|WP_015149412.1|3940168_3941902_+|urease-subunit-alpha
MSYKMDRRAYAETYGPTVGDRIRLADTELFIEVEQDLTTYGDEVKFGGGKVIRDGMGQSPIANDSGAVDLVITNALILDWWGVVKADVGIRDGKIFKIGKAGNPYIQDDVDIIIGPGTEAIAGEGMILTAGGIDAHIHFICPQQIEVAIASGITTMLGGGTGPATGTNATTCTPGPWNIHRMLQAADAFPMNLGFMGKGNSSRPHALVEQVLAGAMGLKLHEDWGTTPAAIDTCLTVADEYDVQVAIHTDTLNEAGFVEQTIAAFKDRTIHTYHTEGAGGGHAPDIIKVCGQKNVLPSSTNPTRPYTVNTLEEHLDMLMVCHHLDRSIPEDVAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGETIIRTWQTAHKMKVQRGFLSPDNRKDGIPSTTEHDNFRARRYIAKYTINPAIAHGIANYVGSIEEGKLADLCLWRPAFFGVKPELVIKGGAIAYAQMGDANASIPTPQPIHAQPMFASFGGSRTATSFTFVSQAALELEIPTQLGLRKPAIAVSDTRKVGKRDMKLNEFLPYIEVDPETYQVWADGQLLTCEPAQVLPLAQRYFLF
>NC_019693.1|WP_015149413.1|3942478_3943441_-|DUF1338-domain-containing-protein
MKQALVAQALWHQLWLDYSHRVPYARIYEAAISEAGGTVANDHIAFRSLALSIETAIGTVNLGISHLEQVLDGLGYVPMGELSFPTQHLYARHYRHPQQDELDLPKLFISELMVDQLPPEVRSHLETTVQSGLDLEGLLGCQSAVQDLRAIDSQSTDPHILAQRLKSLFVRPWMPPVRSHLETVNAASQYGAWVLLHGYAVNHFTGYVNRQNTPAYPDIETTAQALRERGVPMKAEIEGTAEVGLRQTATQAVQESVTIRSRPEGPFLQIPWTYAYYEIAQRFAIEPTPGHPQLFQGFLGPNAAQLFEMTRSQGSIPHPG

Crispr_ID: NC_019693_35

• CRISPR_ID: NC_019693_35
• CRISPR_location: 3942007-3942110
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_35

Consensus_repeat	Method
AACGATTTTTCTTCTTTAAATTTACCACCTTGACAGGGC	CRISPRCasFinder

spacers of NC_019693_35

>35.1|3942046|26|NC_019693|CRISPRCasFinder
CTGCGCATTGCGCCCCTACAAGAAAC

CRISPR arrays and Neighbor proteins around NC_019693_35

CRISPR arrays

The CRISPR arrays of NC_019693_35

>merge|NC_019693|35|3942007-3942110|CRISPRCasFinder
AACGATTTTTCTTCTTTAAATTTACCACCTTGACAGGGCCTGCGCATTGCGCCCCTACAAGAAACAACGATTTTTCTTCTTTAAATTTACCACCTTGACAGGGC

>NC_019693|35|35|3942007-3942110|CRISPRCasFinder
AACGATTTTTCTTCTTTAAATTTACCACCTTGACAGGGC	CTGCGCATTGCGCCCCTACAAGAAAC
AACGATTTTTCTTCTTTAAATTTACCACCTTGACAGGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015149411.1|3937977_3939927_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|227328
NC_019693.1|WP_015149421.1|3957575_3958157_-|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl|CDD|377026
NC_019693.1|WP_015149409.1|3933899_3936554_-|colicin-transporter	unknown	unknown	gnl|CDD|240439
NC_019693.1|WP_015149420.1|3955154_3957500_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|237425
NC_019693.1|WP_015149415.1|3945481_3949591_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|274362
NC_019693.1|WP_083896863.1|3930484_3930994_-|cold-shock-domain-containing-protein	unknown	unknown	gnl|CDD|239905
NC_019693.1|WP_044197238.1|3943822_3945136_-|acetyl-ornithine-aminotransferase-family-protein	unknown	unknown	gnl|CDD|235599
NC_019693.1|WP_015149408.1|3933412_3933667_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149422.1|3958287_3960786_-|DUF4968-domain-containing-protein	unknown	unknown	gnl|CDD|224418
NC_019693.1|WP_015149406.1|3929166_3930045_-|DUF1361-domain-containing-protein	unknown	unknown	gnl|CDD|369208
NC_019693.1|WP_052315745.1|3936894_3937947_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149405.1|3926116_3928576_+|phosphoenolpyruvate-synthase	unknown	unknown	gnl|CDD|273612
NC_019693.1|WP_044195252.1|3962427_3963534_-|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|224662
NC_019693.1|WP_015149423.1|3960898_3962395_-|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143449
NC_019693.1|WP_015149407.1|3932999_3933416_-|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350263
NC_019693.1|WP_015149412.1|3940168_3941902_+|urease-subunit-alpha	unknown	unknown	gnl|CDD|237305
NC_019693.1|WP_015149413.1|3942478_3943441_-|DUF1338-domain-containing-protein	unknown	unknown	gnl|CDD|319960
NC_019693.1|WP_015149418.1|3954096_3954474_+|response-regulator	unknown	unknown	gnl|CDD|381097
NC_019693.1|WP_052315744.1|3931363_3932479_-|hypothetical-protein	unknown	unknown	gnl|CDD|378452
NC_019693.1|WP_015149419.1|3954470_3955115_+|chemotaxis-protein-CheC,-inhibitor-of-MCP-methylation	unknown	unknown	gnl|CDD|381738

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015149411.1|3937977_3939927_+|CHAT-domain-containing-protein	gnl|CDD|227328	COG4995, COG4995, Uncharacterized protein conserved in bacteria [Function unknown].	7.52884e-83
NC_019693.1|WP_015149421.1|3957575_3958157_-|NAD(P)H-dependent-oxidoreductase	gnl|CDD|377026	pfam03358, FMN_red, NADPH-dependent FMN reductase.	1.79127e-47
NC_019693.1|WP_015149409.1|3933899_3936554_-|colicin-transporter	gnl|CDD|240439	PTZ00491, PTZ00491, major vault protein; Provisional.	0
NC_019693.1|WP_015149420.1|3955154_3957500_+|PAS-domain-S-box-protein	gnl|CDD|237425	PRK13557, PRK13557, histidine kinase; Provisional.	1.55365e-74
NC_019693.1|WP_015149415.1|3945481_3949591_+|PAS-domain-S-box-protein	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	8.54906e-57
NC_019693.1|WP_083896863.1|3930484_3930994_-|cold-shock-domain-containing-protein	gnl|CDD|239905	cd04458, CSP_CDS, Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. CSP expression is up-regulated by an abrupt drop in growth temperature. CSP's are also expressed under normal condition at lower level. The function of cold-shock proteins is not fully understood. They preferentially bind poly-pyrimidine region of single-stranded RNA and DNA. CSP's are thought to bind mRNA and regulate ribosomal translation, mRNA degradation, and the rate of transcription termination. The human Y-box protein, which contains a CSD, regulates transcription and translation of genes that contain the Y-box sequence in their promoters. This specific ssDNA-binding properties of CSD are required for the binding of Y-box protein to the promoter's Y-box sequence, thereby regulating transcription.	3.112e-14
NC_019693.1|WP_044197238.1|3943822_3945136_-|acetyl-ornithine-aminotransferase-family-protein	gnl|CDD|235599	PRK05769, PRK05769, acetyl ornithine aminotransferase family protein.	0
NC_019693.1|WP_015149422.1|3958287_3960786_-|DUF4968-domain-containing-protein	gnl|CDD|224418	COG1501, COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism].	0
NC_019693.1|WP_015149406.1|3929166_3930045_-|DUF1361-domain-containing-protein	gnl|CDD|369208	pfam07099, DUF1361, Protein of unknown function (DUF1361). This family consists of several hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown although some members are annotated as being putative integral membrane proteins.	5.12951e-46
NC_019693.1|WP_015149405.1|3926116_3928576_+|phosphoenolpyruvate-synthase	gnl|CDD|273612	TIGR01418, Phosphoenolpyruvate_synthase, phosphoenolpyruvate synthase. Also called pyruvate,water dikinase and PEP synthase. The member from Methanococcus jannaschii contains a large intein. This enzyme generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process. The enzyme shows extensive homology to other enzymes that use PEP as substrate or product. This enzyme may provide PEP for gluconeogenesis, for PTS-type carbohydrate transport systems, or for other processes. [Energy metabolism, Glycolysis/gluconeogenesis].	4.82615e-113
NC_019693.1|WP_044195252.1|3962427_3963534_-|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|224662	COG1748, LYS9, Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism].	1.58932e-72
NC_019693.1|WP_015149423.1|3960898_3962395_-|aldehyde-dehydrogenase-family-protein	gnl|CDD|143449	cd07131, ALDH_AldH-CAJ73105, Uncharacterized Candidatus kuenenia aldehyde dehydrogenase AldH (CAJ73105)-like. Uncharacterized aldehyde dehydrogenase of Candidatus kuenenia AldH (locus CAJ73105) and similar sequences with similarity to alpha-aminoadipic semialdehyde dehydrogenase (AASADH, human ALDH7A1, EC=1.2.1.31), Arabidopsis ALDH7B4, and Streptomyces clavuligerus delta-1-piperideine-6-carboxylate dehydrogenase (P6CDH) are included in this CD.	0
NC_019693.1|WP_015149407.1|3932999_3933416_-|PIN-domain-containing-protein	gnl|CDD|350263	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins. Mycobacterium tuberculosis VapC26 cleaves 23S rRNA in the Sarcin-Ricin Loop, it is inhibited by the cognate VapB26 antitoxin. This subfamily belongs to the VapC (virulence-associated protein C)-like nuclease family of the PIN domain-like superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	5.57271e-15
NC_019693.1|WP_015149412.1|3940168_3941902_+|urease-subunit-alpha	gnl|CDD|237305	PRK13207, ureC, urease subunit alpha; Reviewed.	0
NC_019693.1|WP_015149413.1|3942478_3943441_-|DUF1338-domain-containing-protein	gnl|CDD|319960	cd16350, VOC_like, uncharacterized subfamily of the vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	4.60024e-101
NC_019693.1|WP_015149418.1|3954096_3954474_+|response-regulator	gnl|CDD|381097	cd17542, REC_CheY, phosphoacceptor receiver (REC) domain of chemotaxis protein CheY. The chemotaxis response regulator CheY contains a stand-alone REC domain. Chemotaxis is a behavior known for motile bacteria that directs their movement in response to chemical gradients. CheY is involved in transmitting sensory signals from chemoreceptors to the flagellar motors. Phosphorylated CheY interacts with the flagella switch components FliM and FliY, which causes counterclockwise rotation of the flagella, resulting in smooth swimming. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	3.15452e-29
NC_019693.1|WP_052315744.1|3931363_3932479_-|hypothetical-protein	gnl|CDD|378452	pfam10592, AIPR, AIPR protein. This family of proteins was identified in as an abortive infection phage resistance protein often found in restriction modification system operons.	2.18669e-22
NC_019693.1|WP_015149419.1|3954470_3955115_+|chemotaxis-protein-CheC,-inhibitor-of-MCP-methylation	gnl|CDD|381738	cd17910, CheC_ClassII, chemotaxis protein CheC, Class II. This family contains class II CheC proteins found in proteobacteria, which diverge from class I CheCs in sequence conservation and lack critical well-conserved residues for CheD binding. These proteins are likely to be dedicated phosphatases. The class II cheC genes are not found in chemotaxis operons, but in operons containing more archetypical two-component signaling components, non-signaling operons, or as orphans. Thus, class II CheCs appear to be involved in non-chemotactic two component systems. Class II CheCs lack the first of the two phosphatase active sites of class I CheCs, and retain the second active site of class I CheCs.	4.50123e-56

Protein sequences

>NC_019693.1|WP_015149412.1|3940168_3941902_+|urease-subunit-alpha
MSYKMDRRAYAETYGPTVGDRIRLADTELFIEVEQDLTTYGDEVKFGGGKVIRDGMGQSPIANDSGAVDLVITNALILDWWGVVKADVGIRDGKIFKIGKAGNPYIQDDVDIIIGPGTEAIAGEGMILTAGGIDAHIHFICPQQIEVAIASGITTMLGGGTGPATGTNATTCTPGPWNIHRMLQAADAFPMNLGFMGKGNSSRPHALVEQVLAGAMGLKLHEDWGTTPAAIDTCLTVADEYDVQVAIHTDTLNEAGFVEQTIAAFKDRTIHTYHTEGAGGGHAPDIIKVCGQKNVLPSSTNPTRPYTVNTLEEHLDMLMVCHHLDRSIPEDVAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGETIIRTWQTAHKMKVQRGFLSPDNRKDGIPSTTEHDNFRARRYIAKYTINPAIAHGIANYVGSIEEGKLADLCLWRPAFFGVKPELVIKGGAIAYAQMGDANASIPTPQPIHAQPMFASFGGSRTATSFTFVSQAALELEIPTQLGLRKPAIAVSDTRKVGKRDMKLNEFLPYIEVDPETYQVWADGQLLTCEPAQVLPLAQRYFLF
>NC_019693.1|WP_015149411.1|3937977_3939927_+|CHAT-domain-containing-protein
MKRFKGWTKLLLAMTLVAIAADPAITQTANQSDITGPIIDTPTIVPAGTIEPESTVTPTNTNPDTPDTTPDTPDTTTDTPDTTTDTPDTTTDTPDTTTDLPPGDTSVTPIDSPEEQVITTPVQPVEPINIQSPETTAPVVIPDNPEVPIEAEIPPTVGENNPEPDPTTESANPIEAQILEGAASRTTETEPFSNLSEQEIDRPGYESQLAVADIRVAVQMLEEYQAMQFSNYLEVDLFGETATPDEIAQALYDLWQATGNKSAFIYVSALANQLELVMIFPQNFRVAGGSSELVASTNLAQGLIERTTDIAIRETVPNVSREQLLEQVQNWRSELTNPRRRTSQSYLPVAQSLYQSLIAPMEAQLEANGIETLVFSMDSGLRTLPLVALHDGEQFLLEKYAIALVPSFGLTDVTYSDIRNREVLGMGSAIFDDLNPLPAVPTELQNIVRNFEIGNVFLNEQFTAENFRKTNQENRYGIIHLATHAEFQGGSLANSYIKFFDSRVGLNQIRDLATELGWNTAQNPPIELLTLSACRTAVGDTEAELGFAGLAVLSGAKASLASFWYVSDAGTLGLMSEFYSQLAEKPLKAEALRQTQLALLRGEVRIENGMLLLSNGTTVPLPPELAVQGNLTLSHPYFWSAFTMIGNWN
>NC_019693.1|WP_052315745.1|3936894_3937947_+|hypothetical-protein
MIIQLLLLGILLPLDVAQAGELEPWQAEGFGDKLEFSAHAADLEPVFFQPIQGDRTVVLLTEPNAGEGTVHPQSEIAQGDPATAPEGMTPRQGTPLHRGIPGEQPFIPQRIPFRPRTDVTTTQSKPYAASPAITVMTPSGYGAGWGSAGFGLGLQERTRFTDSSDGVAGFGIGFGNPRENIGLTVGVTVTDLWGDAFEDGSVSLKLHRQLPNDFGIAAGVQGALTWGETDGGTSGYGVVTKRFILDEPENLWSQVYLTLGVGGGQYRSESDIEAGEGTVGLFGSVALRVAPPVSAIAEWTGQDLTLGLSVVPFRNIPLVISPAITDITGSAGDGTRFILGIGYGFTFDRF
>NC_019693.1|WP_015149409.1|3933899_3936554_-|colicin-transporter
MSKPDKLSENPTLESDLASGVIRLKPQEFIHVLDNNTGITRLEVGPQTITLRDGERLILKPQPAIVVPPRHYCIVANPVMRDENGAPSTDPRGQIKLRYGDREIRLSQEPFPLYPGEELAESVTQLQVVETNQALRLRALRDFSETRTIPGETPQTQMIERVAGDEWLFEGPGTYIPRVEVAIVKTVQATIIKTNQALRLFARQNCIDRQGIRRRAGEEWLVREEGAYLPGIDEEILGLIDAYVLTERKALHLKAKRSFTDIFGRQRKAGDEWLVTLEDAEIHIPDVYEQVVGEVQVTTLNDREWCIVVDPIDRNGKPQFGMWEVRQGRITFFLHPGESLHNGIQKVYVLGEQEALLLRADEAFTEGTPENPIHHQPGDLWMIHGPRDYIPPVQVKVIETRKAIPLDKNEGIYVRDIQTGELKLVSGPQAYLLAPHEEPWEKELPPVVEDLLQRKSDPLGDRGEYSGSREETQGRTQNPRKQRDKTRAVVFHVPQNAVVQIHDYKERTARNVFGPDLVMLGPDEAFTVLSLSGDKPKRPNAIKSLALLLGPDFMTDIFTVETSDHARLQLQLSYNWYFEVDKTNEEQTEKLFQVPDFVGAACKAIASRVRGAVAGVQFDEFHRNSARIIRQAVFGVDDEGHIREDFRFRSNNLVITNIDIQSVEPVDEETLKSLQKSVQIAIQITTDAQEAAARHDAERIAQQAKARLERQAIVDKSAAEAERRNLLELEAENAAISSTGQATAEARAKAEAAQIQGQLQVNLATQEAEANRIRAEVELVQLRSRQEAEFAHQQALTNLEIEKAQRMAEITSTEFAQKVAALGPETLRAMAQAGPEMQARLLAGLGLQSVLITDGKSPINLFNTANGLIGGVPSNLGGNGREET
>NC_019693.1|WP_015149408.1|3933412_3933667_-|hypothetical-protein
MSNPPPIRQQLDRELDRLPPESLTQILAFARSLQPQTDYTTLWENWFAEVDTLPLDSQPPNVETAPLNYTDYLVEKYRDQGLNL
>NC_019693.1|WP_015149407.1|3932999_3933416_-|PIN-domain-containing-protein
MILCDTGILITIVDRRQPKHYAYRQAISRYACPLLTTWACLTEAMYLTHRLGGWTMQHQLGKLIVQGGLITYSIDTAQQMTRLLALMEQYRDRPMDFADATLVLVAEETGQRQILTLDSDFLFYRIHNRDSFEIISVD
>NC_019693.1|WP_052315744.1|3931363_3932479_-|hypothetical-protein
MDQILKSYVKNFVDESSLDHLDEATAFEYFVNHTVLSKIHPDPFDVETTIIGGSHDNALDGIAVLVNDHIVTSQEEIDFFRKTLRRFEVKFVFIQSKTSPKFDSGDLGNFLFGVRSFFEEQPAIPMNPQLTNLRTLKDYVYRFSIDMDMGKAPVCEMYYVTTGTWLGDATLEGRIQVEKTAIEGTKLFSQVRFVPVDNEYIKRLYLELRRKVTKEINFEKHTAMPTIGEVHQAYIGILPALEYLKLITDAEGNLIRSLFYDNVRDFQGHNLVNQEIEVTIQDQEQSDRFALLNNGITVVAKNVQQVGSRFSIQDYQVVNGCQTSHVIFLNKDALTDKLFVPLKLIVTNNTEVTNQIIRATNRQTQVYVEAF
>NC_019693.1|WP_083896863.1|3930484_3930994_-|cold-shock-domain-containing-protein
MLVETSQIPYLNSKKIEKYCDSLRGVLWDDDQALETFKKATLLIDKVLAKVTYSQFEATRRKAFTTDLITQLNEDFVTTPAESPALKRPQSAFVAAQVEREQGTVTKFSNIRGFGFIRGKHEQDIFVHFRDIRGDEQRLNAGDVVEFVLLINEKGLNAKAVEIVSRSSS
>NC_019693.1|WP_015149406.1|3929166_3930045_-|DUF1361-domain-containing-protein
MTAQLMDWMTVAWGAMRGNHVFMVWNTFLAVVPLALSFWLFHKPRSQWLRWGVFLILGATFLPSAHRVFRTGIFLLQRISADYLIWILILTLILMSSEIWQLRRSQNSSTVSRSLLWWVGFVAFITFLPNAPYVLTDVIHLITDIRAGYSVWIITLALIPQYLIFMIVGFQSYVLSLIYLTWYMERSGLRRWTGLAELVIHGLTAIGIYLGRFQRFNTWDIVTDPDILVRSVMNDLIGRRPVLVMIVTFVVITVLYWLFKQLTLALMHRNSQPKSAWSPVAPVESPAADSEG
>NC_019693.1|WP_015149405.1|3926116_3928576_+|phosphoenolpyruvate-synthase
MDHLYWLDQIQPSQRYLVGDNPFYLSQMAQQGYPVLPGFVLAAPALREFLETYPWEEPLFAELLSSSVHLNVDDTRQLKAIAQHIREQMMAAELPQQWINDLAIAAEKLSSPGLILSLSVTLPQNTPSPVKFSGLVESYVCLCDPEEIALGVLQTWAELFRARSLLYWQRSQIELRALNLAVLVQPLHSAITSGTLTYTPAHCEIKATWGLPLSIKLGQAIPDWYQIELEKGNAIAQSLGNKHLGYDLRWNSTPPDELTAETSLLSPYSCLQPYLVSDEQQQEFSLKPRELETLGAIARNLGSHLNRQFSLEWTLVKATEQSPEQIYITGVEVGNPLPSLEMTAPVDPPSSPKSVPVTAIEGEEMPQIILGTGAAKGVAVGLVYCIPSPTEVLEHIPPGRILIAKEIAPHWLHIVRQAAAVVTESGGMTSHAAILAREFGIPAVVGAAGVMQAIATATEICVNGDTGEIFILPAGTVPPSPVRSPQPVATAVSIPEPMPSPDSNPLSSPFPTATQLLVNLSHPSSLDRIADAYLDGVGLLRSEMMALEIFQSEDPYQWCDHHKNQEFIHRISDPLKRVAEFFFPRPVFYRSLDLRGYDLPGMRSPGQTSINSNRSAQTLGVHGAFSYLLDPTLFDLELETLAKLQQEGLTNLRLIIPFVRTVEEFIFCRSRVQQFKLDRVRDFQLWIMAEVPSALFLIPDYVQAGVQGISIGTNDLTQLLLAADRENQQMSQVFDPRHPVVMRAIHQLIQQAKAAGIPCAICGGAPTRYPETIDTLVRWGIDGISVEPEAIVRTHQAIARSEQRILLETARRDSEDCPF
>NC_019693.1|WP_015149413.1|3942478_3943441_-|DUF1338-domain-containing-protein
MKQALVAQALWHQLWLDYSHRVPYARIYEAAISEAGGTVANDHIAFRSLALSIETAIGTVNLGISHLEQVLDGLGYVPMGELSFPTQHLYARHYRHPQQDELDLPKLFISELMVDQLPPEVRSHLETTVQSGLDLEGLLGCQSAVQDLRAIDSQSTDPHILAQRLKSLFVRPWMPPVRSHLETVNAASQYGAWVLLHGYAVNHFTGYVNRQNTPAYPDIETTAQALRERGVPMKAEIEGTAEVGLRQTATQAVQESVTIRSRPEGPFLQIPWTYAYYEIAQRFAIEPTPGHPQLFQGFLGPNAAQLFEMTRSQGSIPHPG
>NC_019693.1|WP_044197238.1|3943822_3945136_-|acetyl-ornithine-aminotransferase-family-protein
MDEILTGQSLPRRPHLVTPLPGPRAQELVQRDRAVTSPSYTRGYPLVVARGEGCSIQDVDGNVFLDFTAGIAVTATGHAHPQVVQAIQAQAAQLLHMSGTDFYYEPMVELAEQLAKLAPFPQGAKVFFSNSGAESNEGALKLARYATGRSQIVAFLGAFHGRTFGAMSLTGSKAVQRQGFGPLLSGITHIPYGTHASLDYLEFQLFKTVLPPEELAAVVVEPIQGEGGYLVPEDGFLARIREICTRHHCLMVVDEVQSGMGRTGKLFAVEHWNVMPDIITLAKGIASGLPLGAILARPELMTWPPGSHATTFGGNPVACAAANATLQLLTQGVIANATQMGELLQSGLSKLAHRYPQLSQPRGKGLMVAVDLLDESGAFNPSLRDRAIDEAFYHGLLLIGCGKSAIRFCPPLVVDAEQIQVALEILDTCFAKLLTTR
>NC_019693.1|WP_015149415.1|3945481_3949591_+|PAS-domain-S-box-protein
MIKISPSVLLRLLSKLSQLCYPKNQPSTPLLQFLHSVGIALVSVTLATVIKSALAPLILGESPFLVYFAAIMVSAWFGGPKAGVMATLGAGLVSSYLFLSPGYALIESSPSQIFRLILFLIEGSAIVIAIGSLQHTKQQFAQSARTAQQHFESFLQSEQRFHLLVDGIEDYGLYMLAPDGRVNSWNPGAERLKGYAPEEIIGQHFSCFYPPEAVAEGQPERDLKQAAEQGRLEQEAERLRKDRTRFWVHEVITPLFDKQGNLYGFSKISRDITESKQTEAELRASEQRFKTLAESTVEGILFYEGDCIIAVNRSLEKIFGYDPDDLNGLPLASIFTEETVALMVNDCQWMQEGASEAVGIKKEGTMVSLEAVIQPTLYLGRSVWMASVRDISDRKRAEADLQQTLKELSDFQWALDKSAIVATTDAKGTIQYVNEKFIEISKYSESELIGQDHRLINSGYHPKEFFINLWVTIGRGEVWRGEIKNRAKDGTYYWVDTVIVPFLDSHKKPFQYLAIRYDISQRKQAEEALRDSEKRFRDMADTAPVLLWIANCQGQWTFLNKWGLNFIGALIEADPDLNHRDRIHPEDQVQCVLSYQQAVRVGQPFTQEYRLQRSDGAYRWMLETGVPRWNPEGNLVGFIGSAIDITPLKQADTERMKLLQREQSARTQAEASEQYYRFLSEAIPQMVWTALPDGTLDYLSHRWSEYTGLSEAELLGWGWEPIVHPDDLAECNQRWAACLENGEPYEIEARMRRGCDGAYRWHLGLAVPMRDHQGAIVKWFGTNTDIHERKQVQQERMELLEREKAARILSERATTMVHRLQAIVDVAIAPLSLDDLVQELLDRLTVVLEVDAAVILLVNEDQTALIVTATKGLDLEQPLSPNIPIPMGLGFSGQIAQTRQPMRIDHDAYTQVISPLFRHKKIESIMGAPMLLEDRVLGVLHVSTESRREFMAEDVYLLQLVADRVALAIDRANLYEAQQQARDRAEKANRLKDEFLAIVSHELRTPLNSILGWAQLLRARTLKEETRDKALETIERNAKHQVTLIDDILDVSRIMRGKIRLTRVPLYLETLVEQAISTVTPAAEAKSIEIYTEFNSHGQPILGDTSRLHQIVWNLLSNAVKFTPNGGRLTVAIEQVGDYLEFRVQDTGIGITGDFLPHVFEGFRQANSSSTRTHGGLGLGLTIVRYLVELHGGTVHAFSQGEGTGSTFTVALPIGVSQNSPLDLDSMIGDEKAIANCALNLAGLQVLVVDDDRDTGELIAQVLAEYGVQTTVVLSAAEALAATERSRHDILISDIGMPEEDGYVLIRKIRQREAGYSRPIPAIALTAFAREEDRQQALLAGFHLHVAKPVEPLKLAKALADIAQQTGLI
>NC_019693.1|WP_015149418.1|3954096_3954474_+|response-regulator
MAKILIVDDSTLSRGILRRILQTEGHSIIEAKDGLMGIESYYIEKPDLVLLDIAMPDMQGTEVLEKLRAFDDRARIVMATADLQELTRAAVMAAGALGYLTKPYNPDVVLDIVNQVLRGIPGGVG
>NC_019693.1|WP_015149419.1|3954470_3955115_+|chemotaxis-protein-CheC,-inhibitor-of-MCP-methylation
MKLTETQKDALSELLNMGFSRTASALSELTGHRVLLEVPQVSIHPIEELSAKLGTFVKGEIATVQQIFTGRVSGNALLLLNYDGAVQLTELVTPEQNIHRDRLDASAAEVLTEIGNILLNACLSVFGNLLQMQISFSVPRLHLEALDGLLHSLSIGKAEMRYAMVVYTGFRMKENSIHGYLVMVLSVVSLEKLLEEIDNWVREEIAPPNLSISS
>NC_019693.1|WP_015149420.1|3955154_3957500_+|PAS-domain-S-box-protein
MNRITDPFNYNQDLLHWVNDLADRGIFTTDAQLNIQSWNHWLELYSGLNADRVVGQNLLEIYPELKHRRLDRFFDQALAGQVAVLSQRLHGFLLPMLPADVYKDVPYMLQSAKIAPIVEASRVIGTIATLEDVTERVLRESELHHQIKELKRTESALMATQSQLQYLLSSSPAVIYTCPAKQPYSPTFVSENIVEHLGYRPEEIVGDCSFWRDRIHPDDAPELFSSIKLLYQRGHSQSEYRFWHPEGSYRWVRDEMKLICKGEHQVEEIVGALYDITDRKRVEEQVRQQAALLDIATDAIWVKDLNQTIQFWNKGAEKLYGWTREEASAQSSSRLFEVKSAEELNRIEQTVLTTGEWHGELEQITKAGKSITVASRQTLVRDDRDRPCSILSVNTDITEKKQLEAQFLRAQRLESIGTLASGIAHDLNNILTPILGAVQLLQMFPLNAQQMRLISMLEINTLRGADLLKQVLSFAKGLDGDRTLLQIKHLIDETTAIARETFPKSIEITTAIDPQLWLISGDPTHLHQILMNLCVNARDAMPNGGILSIEAENLNLTPSDLILDPAAQVGSYIKLTIRDTGTGISPEILDRLFEPFFTTKALGQGTGLGLPTVRGIVKNHGGFLLISSQLGQGTAFTVYLPAIQGTEALASEPQELPFGAGELILVVDDEVAICEIAQALLQKFGYHVLTANDGMEAISLYSQRSSEIAVVILDMMMPFMDGMLTLKALQKINSSVKVIAISGLLSNFPLAELGDDNSFTYLSKPYKTRDLLCLIRKQIEQ
>NC_019693.1|WP_015149421.1|3957575_3958157_-|NAD(P)H-dependent-oxidoreductase
MSNPPKILAFAGSAREGSFNKKLVQIAANGARKAGAEVTYIDLRDFPIPLFDQDLEAAEGMPSYAQELKSLFFAHQGLLIASPEYNSTISPLLKNAIDWVSRPAPGEPMLAAFSGKVVAIMSTSPGALGGLRGLAQLREMLANINMIVLPNQKAIPQAMEAFTESGMLKDPNQQEAVENIGAKVAQMLAKLNA
>NC_019693.1|WP_015149422.1|3958287_3960786_-|DUF4968-domain-containing-protein
MNILKQISLKLRFIRLERFIASLIYTFQRDWADRQYHSSQKVQPLTTPGRLLTVEKTSQGAQFSFEKAQVEIEFLSPELVRVNWQPGLAPVPYGIVQQDWPEVDLQLQDTEQGKIIRSDRLKVIVKPEGGIEFQDANGRVLRQELPPQRRGEAWQQEALLRSPEQIYGLGERAAPFNLRASQNPRYQMWHYDAGGKYGPGSDPLYLCIPVYMGLHDNGSYLVFYENSFSATFTLGDSAIAAFAGGALRYYMIAAEPAKAIALYTQLTGRPPLPPRWAFGYHQSRWGYETEEAVRETAQGFQKHNLPLSAIHLDIDCKDNFRSFTIDPDRFPKLREFNQEMAEEGVNMVAIVNPGVKRDRRSQLYREGVSQDIFCKLPNGNIVHAPVWPGMSAFPDFTHPLARHWWSRQYEYLLDMGIAGFWHDMNDPGVFALWGDATLPKATQHFMEGRGGIHLEAHNIYGLQQARAGYEALRDSRPSRRPFIVSRSGWAGLQRYAWTWTGDIETSWGGLGQTLPTVLGMGLSGIPYTGPDIGGFKGNPSAELYLRWFQLSTFLPFCRTHSANNVKPRTPWGYGLHVLDCVRSLLQLRYQLIPYFYTLAWEATHQGYPPVRPLFWSEPENSELWGMDDAFFLGDGLLVYPIVKDKVRSRLAVFPQGQWYKFTDDTIIEGSQRLRLEVPLEEIPLFVKAGTVLPMEQGEHLTLHLYPPTEGNSRGFLYSDAGDGYGESRLDQIHLERTPEGLAIAWESQGDYPFPYSSVELQIHGMAVQQVWMDGTEVEFQQPQEQPRTAMRIAPGVSISGDKFKRVQIQGEFRQPDPSSSFNPRQSYPTNGL
>NC_019693.1|WP_015149423.1|3960898_3962395_-|aldehyde-dehydrogenase-family-protein
MHSCLNYIDGHWLAPASGETMESRNPAHWRELVATFPRSGDIDIEMAVTAARRAYRTWRRVPAPERAEFLYRFGELLRDRKAELAYLMSQEMGKPLTEANGDVQEGIDCAFYYAGEGRRLFGQTTNSEMDNKFAMTVRMPIGVCGLITPWNFPVAVPCWKAMPALVCGNTLVLKPSEDTPAVTHLLFQVFHDAGFPPGVVNLVHGLGEEAGKALVEHRDVNLISLTGSSQTGAEVAAICAKQHKRVCLELGGKNAQVVMEDADLELALEGALWGAFGTSGQRCTATSRLLLHRDIKDKFTEMLVDRTQKLRLGPGTDPNTEIGPIVNATQLNTIEEYIEVAHQEGAKVLIGGNRTTAGTLTGGFFFEPTILDGVMPHMRVAREEIFGPVVALMEISSFEEAIAILNDTSYGLSSSVYTRDVNRAFQAMRDIEAGITYINGPTIGAEVHLPFGGVKQTGNGHREAGTAALDVFTEWKTVYVDFSGRLQRAQIDNRGPVT
>NC_019693.1|WP_044195252.1|3962427_3963534_-|NAD-dependent-epimerase/dehydratase-family-protein
MSQRVLIIGGRGRIGSSIAQDLITHTDAEITITGRDTTSGKSVEETLGDRLKFRALHLDDRAGLEQAIAASDLVVHSAGPFHHRDARVLQLCIDRGVNYTDVSDNRGFTRRALALQESAAQAGVTAVINTGIFPGISNSMVRQGVEQLQEADRIHLSYVVGGSGGAGVTVMRTTFLGLQNPFDVWIDGEWQQVQPYTAREIIEFPQPYGKVGVYWFDMPEAFTLPDSFPVKTAITKFGTSPDLYNHLTWMVANLWPAAALKNSAVVEFLSQVSYRMTGVTDKFSGTGVAVRSEVNGRNAEGEPATVCSAVVHHSAAVATGIGTGTIAELMLNGKLTKPGVWPVEQALSTSLFESIMTTRGIEIVHHWL

Crispr_ID: NC_019693_36

• CRISPR_ID: NC_019693_36
• CRISPR_location: 4290387-4290476
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: PD-DExK

Consensus repeat of NC_019693_36

Consensus_repeat	Method
GTATGCAATACGCCCCTACAAGAAAC	CRISPRCasFinder

spacers of NC_019693_36

>36.1|4290413|38|NC_019693|CRISPRCasFinder
AAGGATGAGGCAGGATTCCATTGACGGATAAAGAGGGC

CRISPR arrays and Neighbor proteins around NC_019693_36

CRISPR arrays

The CRISPR arrays of NC_019693_36

>merge|NC_019693|36|4290387-4290476|CRISPRCasFinder
GTATGCAATACGCCCCTACAAGAAACAAGGATGAGGCAGGATTCCATTGACGGATAAAGAGGGCGTATGCAATACGCCCCTACAAGAAAC

>NC_019693|36|36|4290387-4290476|CRISPRCasFinder
GTATGCAATACGCCCCTACAAGAAAC	AAGGATGAGGCAGGATTCCATTGACGGATAAAGAGGGC
GTATGCAATACGCCCCTACAAGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015149647.1|4304462_4305092_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_019693.1|WP_015149637.1|4289221_4290151_-|hypothetical-protein	unknown	unknown	gnl|CDD|316753
NC_019693.1|WP_015149638.1|4290521_4291685_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149646.1|4303512_4304466_-|hypothetical-protein	unknown	unknown	gnl|CDD|237372
NC_019693.1|WP_156823873.1|4288041_4288197_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149635.1|4288429_4288678_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149629.1|4277242_4277848_-|hypothetical-protein	PD-DExK	mkCas0061_PD-DExK_CAS-I:CAS-III	unknown
NC_019693.1|WP_015149630.1|4277899_4280746_-|replicative-DNA-helicase	unknown	unknown	gnl|CDD|273206
NC_019693.1|WP_015149640.1|4296357_4297860_-|hypothetical-protein	unknown	unknown	gnl|CDD|225288
NC_019693.1|WP_015149632.1|4281854_4286612_+|ATP-binding-protein	unknown	unknown	gnl|CDD|214643
NC_019693.1|WP_156823872.1|4286911_4288045_-|serine-hydrolase	unknown	unknown	gnl|CDD|365903
NC_019693.1|WP_015149648.1|4305397_4305874_-|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380353
NC_019693.1|WP_015149639.1|4293230_4296143_+|amino-acid-permease	unknown	unknown	gnl|CDD|236901
NC_019693.1|WP_015149645.1|4302863_4303154_+|DUF1778-domain-containing-protein	unknown	unknown	gnl|CDD|370057
NC_019693.1|WP_015149631.1|4280888_4281347_-|50S-ribosomal-protein-L9	unknown	unknown	gnl|CDD|234659
NC_019693.1|WP_015149636.1|4288667_4289090_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|225266
NC_019693.1|WP_015149643.1|4301946_4302213_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|198034
NC_019693.1|WP_044197323.1|4297838_4298243_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149644.1|4302194_4302602_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350250
NC_019693.1|WP_015149628.1|4275869_4277066_-|DNA-(cytosine-5-)-methyltransferase	unknown	unknown	gnl|CDD|365904

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_015149629.1|4277242_4277848_-|hypothetical-protein	PD-DExK	mkCas0061_PD-DExK_CAS-I:CAS-III	4.7e-68	223.4	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015149647.1|4304462_4305092_-|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	8.54453e-37
NC_019693.1|WP_015149637.1|4289221_4290151_-|hypothetical-protein	gnl|CDD|316753	pfam14261, DUF4351, Domain of unknown function (DUF4351). This domain is found in bacteria, and is approximately 60 amino acids in length.	0.00269566
NC_019693.1|WP_015149639.1|4293230_4296143_+|amino-acid-permease	gnl|CDD|236901	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS.	5.20004e-51
NC_019693.1|WP_015149646.1|4303512_4304466_-|hypothetical-protein	gnl|CDD|237372	PRK13386, fliH, flagellar assembly protein H; Provisional.	9.55093e-05
NC_019693.1|WP_015149630.1|4277899_4280746_-|replicative-DNA-helicase	gnl|CDD|273206	TIGR00665, DnaB, replicative DNA helicase. This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair].	1.40323e-137
NC_019693.1|WP_015149644.1|4302194_4302602_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350250	cd18683, PIN_VapC-like, Uncharacterized subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.30029e-39
NC_019693.1|WP_015149640.1|4296357_4297860_-|hypothetical-protein	gnl|CDD|225288	COG2433, COG2433, Uncharacterized conserved protein [Function unknown].	0.00576787
NC_019693.1|WP_015149632.1|4281854_4286612_+|ATP-binding-protein	gnl|CDD|214643	smart00387, HATPase_c, Histidine kinase-like ATPases. Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.	0.00971323
NC_019693.1|WP_156823872.1|4286911_4288045_-|serine-hydrolase	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	2.00406e-65
NC_019693.1|WP_015149648.1|4305397_4305874_-|cupin-domain-containing-protein	gnl|CDD|380353	cd02224, cupin_SPO2919-like, Silicibacter pomeroyi SPO2919 and related proteins, uncharacterized sugar phosphate isomerase with a cupin domain. This family includes proteins similar to sugar phosphate isomerase SPO2919 from Silicibacter pomeroyi and Afe_0303 from Acidithiobacillus ferrooxidans, but are as yet uncharacterized. Structures of these proteins show a cupin fold with a conserved "jelly roll-like" beta-barrel fold that form a homodimer.	2.31976e-44
NC_019693.1|WP_015149645.1|4302863_4303154_+|DUF1778-domain-containing-protein	gnl|CDD|370057	pfam08681, DUF1778, Protein of unknown function (DUF1778). This is a family of uncharacterized proteins. The structure of one of the hypothetical proteins in this family has been solved and it forms a helix structure which may form interactions with DNA.	5.87707e-17
NC_019693.1|WP_015149631.1|4280888_4281347_-|50S-ribosomal-protein-L9	gnl|CDD|234659	PRK00137, rplI, 50S ribosomal protein L9; Reviewed.	4.75165e-55
NC_019693.1|WP_015149636.1|4288667_4289090_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|225266	COG2402, COG2402, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	7.75221e-24
NC_019693.1|WP_015149643.1|4301946_4302213_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl|CDD|198034	smart00966, SpoVT_AbrB, SpoVT / AbrB like domain. This domain is found in AbrB from Bacillus subtilis. The product of the abrB gene is an ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. AbrB is thought to interact directly with the transcription initiation regions of genes under its control. AbrB contains a helix-turn-helix structure, but this domain ends before the helix-turn-helix begins. The product of the B. subtilis gene spoVT is another member of this family and is also a transcriptional regulator. DNA-binding activity in this AbrB homologue requires hexamerisation. Another family member has been isolated from the Sulfolobus solfataricus and has been identified as a homologue of bacterial repressor-like proteins. The Escherichia coli family member SohA or Prl1F appears to be bifunctional and is able to regulate its own expression as well as relieve the export block imposed by high-level synthesis of beta-galactosidase hybrid proteins.	0.000708745
NC_019693.1|WP_015149628.1|4275869_4277066_-|DNA-(cytosine-5-)-methyltransferase	gnl|CDD|365904	pfam00145, DNA_methylase, C-5 cytosine-specific DNA methylase.	3.9588e-62

Protein sequences

>NC_019693.1|WP_015149637.1|4289221_4290151_-|hypothetical-protein
MTRFIYDEFTKKYIQELLRQLGQMETSKTMASQRREIDIFFTPNPENIGDASHLGLLGRLATTSAVFEPFSNPVKPREICSCLVKLLNIKAEFERQATREKRRITPAESPRLWMMTPTASAAVLADFGATLDLENFPGGVYFLPKGLQSAIIVLHQLPPTPETLWLRILGTGKVQKQALQELYQLPPDNPTRETTLELLYNLREMLQARQNLAPEERELIMELSPLYLQRLQTVKEEGIQQGVQQGIQQGVQQGQRRLVESLLQVKFGALDAELAQIIEALIEIPPLEQAQLILQLSREELLARFSRDF
>NC_019693.1|WP_015149636.1|4288667_4289090_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MKNSTFIDTSGWANLFIKTEPHHQQAVQWFTQAREQNYLMVTTNYIVLELVALLNSPLRVPRPQIFQYIDAIHSARYLQLVRVEQQIENAAWELLKKRLDKNWSLVDATSFMIMQQLGITNALTSDHHFDQAGFIRLLNS
>NC_019693.1|WP_015149635.1|4288429_4288678_+|hypothetical-protein
MTRKISLELPDDLSQRLEAKAQVINISLEAMILNSLEELATQPDDPIAALIGTLSAEHHDIASRHDDYIGQAINSQELPGEK
>NC_019693.1|WP_156823873.1|4288041_4288197_-|hypothetical-protein
MDEQRSPADRSLIQELINAKWAQLMRAVAEMMAQQGLGNAGGLRNLMSKSR
>NC_019693.1|WP_156823872.1|4286911_4288045_-|serine-hydrolase
MNPKPRRTSFMITPLYLLGSLLLSSCFAIPLGESGAEVGESSEFAFGAKRTAEIDRLVADSLWENGPGVAVLILDQGAIWQKGYGFSDVVAQRPITPDTVFDLASVSKQMTAIAILILMEAGELELEDAVIQHLPDFADPNPDNPILIADLLYHTSGLADYTGDAWQGTDAAFARLTVEDHLQWLNTQEIEGDRAVEFEYNNSGYALLALIIERVSGQSFGDFMAEQIFMPLGMNNTVVFADLAQQIPNRAEGYAVSPEGKFNPSALPSVIAGDGNIFTSIADLARYDQGLRNGDLVEPATLQLAFTSGTLDNGESFAYGLGWAVGADYVEHSGSWYGTSTFYRHYIEKPVTIIVLSNDENYPVDELVDDLAKLLGY
>NC_019693.1|WP_015149632.1|4281854_4286612_+|ATP-binding-protein
MSNRFTAHHLIQGIFDDIERLEEYAQKMIAKFVTDLTGDSYSEQERFIFELLQNADDLPTIIGQVHVKLVILENHLLVLHNGKPFDDENLRAICNRSESTKSKNSDQTGYKGIGFKSVFHDSQCVYINSGDFSFKFDRNSTKHQNPAQTPWQIKPIWVERDEYPDEIQAYSDFFESPVATALKVSPEKINDYKEKIKKLFSDPRLILFLRHISSIEVYGLNDLSLDIKVIKLKQQDIYTIQYTALPSEQTIETQWIIKNFELPVSQNIREAMKNDEKVPDKLKSIQNSKLTFAVEIVNNQIHPVDNSVLFNYLPTNVKADQFPFLINADFLTTAGRETIHVDHTWNCFLFEQIGYYIFEWIAHLAKQPEYKNFITAILPKKFKQSPTELEEKFNRGFDKAVEEVPFIPAEEVPDLLKVCEAVIDKTQICKLIPEKLILDFLNLSGHFVNYFLTGREKLEDLEKINTFDSKNLSNLIRNHQELRQKIKLEPEYNFALVEHIYKHYKQKLETDSFYNVSFLLSEQGELQSPQNLYFQVNHQEKQELSFTSLNFLHPFLNDKISEDPHFKNWAKQSLKIKNFSGLEFLSKRILNRQFKPDINPQSRTTLVAYIRFIFKYHTKLNQSEYLALNKLVLIHENFDGKCYINEAAKCHLSDFYNPDGIKFKSVAENIGGEYFKFLVEDYCGDSSQLYEWKKFFTSIGVKSLNAILILKENIIPRISNNKITDENLIPITLFVFKTWQSQSLSDLELKHLPLKTNNGLKPADQCHIIEEQSNLIREDSDNSAIKLQNVVDIGAYISSEDFAAFRQFLISILKVKVTTYIEFIRQTIKQISKNPQLVTAENTISVVREIFSYRNCLTDEELQNLKVLNLLLKDGKSVAKAENCYLSSDYQPTFNMEQIYASTGFSGFVSAQYCKHGNYTEWKKFFIRIKVMQEFNFTNEEWSLDTLLAALKDSSIHKPYKEYLEQQKSVEKKATHLQNYFGIKHIFGTDGYYLNIPEFARGVLTYISNQWDELNLNSKAFLVDKDSGTQREVDTLFEFLFKRISSIPCLDGICHPSANGIYSSNFKTIVEECFPVLSIKLNPNFEKFLGIKQEIDVADCLPILDDIRDKFSGDENNQKLRLQNLLKYLTRSVIQDGKEIDKNQIQDWIERGGQLLSDRDQFNEVRNLFYLDPELGIFPKNHSQLLQIPSFSEDRESIVKTVVDLFDIPLLNREKTQKKFINHQEDDKLKQLILERSIFIGIFLEGSRSPEIEEHIQNQVQETKFYNPQKILLSFDEIDYQASIPNYWDNETRSLYYIRQWNNINNDKFGDLILKVLQLDKEIPSQVLLRLLDYNWKDAKEYLQENGCDVSDIREEDQREILAQTVSPLEIEQTEAKENELETTSSALTRSPDGTGENREAVGKWGEEQAKQFYERMGYKPEKINDFSKAGYDFKCFSWQNNPQKLWVEVKTISSNTPIIRLKPSQWEKMQTPKKRQLINPHTHIVEPSFEYQLLIVAHTNCSPDQIIQISDPWEVLKLFVSRLYDEEVQNKTEAKYKKLVEVIVGFQQSEKGETNEILLNWHRLLEQAKIDERIKIHPRGNLNV
>NC_019693.1|WP_015149631.1|4280888_4281347_-|50S-ribosomal-protein-L9
MSKRVQVVLSQDVRKLGRSGDLVEVAPGYARNYLLPQGFAVRTTPGILRQVERRRELERQRLLEEKQQAQSQKTALETIGRFTISKSVGEGDAIFGTVTDREVAEVIQAATNEEIDRRGITLPAISKTGFYKAQIKLHPDVTAEVEIQVVAG
>NC_019693.1|WP_015149630.1|4277899_4280746_-|replicative-DNA-helicase
MAEPLNFQGYSDRLPPQNIDAEESILGGILLDPEAITRVLDRLPPDGFSITAHQQIYKAAVALHFQGKATDLMTVTSWLADHKLLEQVGGQSKLAQLVERTVSAVNIDQYAELVVDKYMRRKLIQGGHKVAELGFDTTTELATLLDKAEQTIFSLTQDRPQQGLVSISETLIHTFENIEIHQQGLALPGLTCGFYDLDAMTGGLQRSDLIIIAGRPAMGKCLGRFSELILSDGSVTTIEEIFNRRQAELLTLADNWKFTFTQPSAFVDDGIKPVFRVKTRLGRYIETTITHPYLTMKGWRRLSELQVGDNIAVPRKLEVFGTEILPEYQVKLLGYLIGDGCLTHTSPQFTNSNILLQEEFTEAVNKIAGLKVRLETSQGTRTPTLYVTGDLDFIAENRQVFAQRLKTVIQSHSLSAKAIAQSLGVAPSLVCLWMQGKCVPNAEDFRELCNLLNVESEELTPHGLAAISKNGKNPLTLWLQELGLWGKNAHQKTVPSIVFQLNRSQIALFLNRLFATDGWASVLASGQAQLGFATVSEKLARQVQHFLLRFGIIAALKSRSVSYNNSRYPSWQLDITERESIKTFIAEIGIFGKEVAIAKVAEVLTTRKPHANRDLIPVEIWDQLAAVKGDEPWTVLAQRAGIQGYSNIHVGKRALSRERLWILATALENLPLQQLATSEVYWDEIVAIESMGEQQVYDLTIPETHNFVANDICVHNTSFALNLGRNIAEFHKLPVAVFSLEMSKEQLVQRMLSGEAGIESNRLRSGRIAQNEWEALSIAIGNLSELPLFIDDTPNITITDIRSKCRRLQAEQGGQMGLILLDYLQLMEGSSPDNRVQELSRITRGLKQLARELNVPIITLSQLSRGVEARTNKRPMMSDLRESGSIEQDSDIVVMLYREEYYNPDTPDRGIAEVIITKHRNGPTGTIKLLFDPQFTKFKNLARPQQHY
>NC_019693.1|WP_015149629.1|4277242_4277848_-|hypothetical-protein
MFYREFTTIVKVKQAFGLTTVEGVKFFPPIEPIAPSLTLASFLEDSLPVAVATGSEKARSELIISPILLEVRKILHRQISLFSGEEFTVDPMTGLNGVCDFILSSSPELLEIEAPVVMIVEAKKADLKTGIGQCIAEMVAAQKFNELKENAIPAIYGTITSGMQWRFMKLEGQTVTIDLTDYPLVPVEQILGFLVWMVQQG
>NC_019693.1|WP_015149628.1|4275869_4277066_-|DNA-(cytosine-5-)-methyltransferase
MKSQGEKSQGWKITEAERAVYRNRSQASSAAKAKALRGEGPKPIHPINVPKLHPEDLMPQLPPHGLRSLSLFSGGGGLDLGFDRAGFTHVASYDILPDAGKTLTQNCPHWTVFAGEPGDVTQIDWRSYRGLVDIIHGGPPCQPFSVAGHQKGKADRRDMFPEFVRAVLEIEPLAFVAENVTALLGKKFSSYVADEIEKPLSEKYYLTKFILFAPNFGIPQIRKRVFFVGFKTDKIAANYQPPQGTHHWEDGSRTGPNKPIQLDLFSPGKPSKRPRCIGIREALGLPDIGFDALAPTIRSGLTGPRHTTSVLSSVSAQKNWEKLQIWPNGVAANREQAHLFVAKNGHFRLSVADCGIIQGFPESWIIEGAVYMALGQIGNAVPPPLAYRVAESIYQALS
>NC_019693.1|WP_015149638.1|4290521_4291685_-|hypothetical-protein
MFKQKFEDYEEFISALPKLEAKLSPLASPESHFFLEWSSGHYRVANLANFLSLLQSFSHRGGRMQRLVAVTRFFLYSHPTIETHATSIRLGSDVSKGLRLFYPHVTLKVRQKSRSEGDNPTKPWFINEQEGRDLLRQKLGDSTAVRVPQVFAAGEYGNLSYLLEERLSIRVLNPQKREDRQLLIDRFLPSLLTWYSSPQWQPYSSVFSETITDLLEDALRSAAIADLNPAQSQRFYKLVDQLPELDMAVPFVAGLGDMCLSNACVGPNEELVLMDWEAHHTRPVALEFDRLIRPFGIGSEVHQAIRQAYSQQFEISPELFDRQLYLFNLIGCSRQLLSVSTLKDPQKRQYSLHLSQILLKAAEEFAQTAQHGSGDKSISSPVLRSIS
>NC_019693.1|WP_015149639.1|4293230_4296143_+|amino-acid-permease
MDTQTLPLVRLKRSLSFLETWGFGLSGLLLWLGPAPAMNAALGAQAIFVWIPAAMIGCLLNLQVQHLGMRWPDMSGGTPNYAARLLAKYPIAARYGAVGYWLGWVSVPPMNAIILSDLVIANLSPVGLSLPENLLRIGFTVIPYIVAFSGTRTLSILHLCFVIPAVGFLLTFGLQGLGWLTFAPASPGILPRDWGQFNLIEWAKWFFVAVYAAYGCETASSFVADSQQPRRTLKTLSFAAVLLPIVYVGGSWILMCLASDPNLGNNTFLHLVAGAQPFWGSAASTLVTFLLSAGCLLSSTTAICNSPRVLYQLALDGYMAPVFGVVSSRGVFGPGLLFTFILSLICLLWGDVSHVVMVTGTGYLSSMMAVHLSLWLNRDRPEVKWPRWSLLFLIVESFVMVVGGFAWGWNYWLMGLLLAPTILVVDALIRRRSVPLFRVEWWLALYRRRSSGQFKNFDVLQVGVLLFLICGALTVGWVVRTALAQSGLGVGSELYVLLLLSIALVGVAIACWTTLPQIASILEAQEATEHLFKVALDPIMVIDEQGAIARANPAACELFGVSAQTLAGVKMAELLPGLRDAPQFWPPRCEQLVNPTAVAFPQDQSSVQPFAQKTVEVSVSSRTHWDQIEYVVILRDITPRKQAEAKLKAAFARQEQLTATATRQAQELKTALSELKQTQSQLIQTEKMSSLGQLVAGVAHEINNPVNFIYGNLTYTSDYTTDLLALIHLYQASYPEPNPEIDALIDQIELDFLTEDLPKMIASMKVGAERIRQIVLTLRNFSRIDESDMKPVNIHEGIESTLLILQNRLKPTAQYPRIEIIEEYSELPEVECFASQLNQVFMNILSNAIDALHERVKAAILTPDGGEVPSPRITIRTAALDSHWVRIAIADNGPGIPESICNRLFDPFFTTKPVGEGTGLGLSICYQIVVEKHGGRLYCASEPEQGTEFIIEIPVRTVKKTAQREVIRAI
>NC_019693.1|WP_015149640.1|4296357_4297860_-|hypothetical-protein
MDSEKSLIPLVYAPNLHLFAFHLWRGLTGEPDSLAPHPKQLWERGDDILKALGFAEPLHIPGYPDNSPEPLGAQVNLHPQKQLELTGKLPDSDLPIAGLLLTHRLYDSYSLTFNLRRPETENGEKTAPVPISFWQKLNTDRLLFLPHVVQSSLGQTLLLTAFLPESETDKSPENLQDFAGNCVKQVSPSHKNRPPLQQLGELFGSPIFEFGGQVLEANLGEEAQVQPHILILLFRAELPSEKFVDAYREFINLFYYRNKVISAYRETRTLYQKTYSIYTDLEKKVKSFKQELEKNKTRLALSQEELEDLKQVLKKLAQLDLEYARLLRNYKHSRNTIAINTKNYQVSLEAIVKRLKEQGYGVKPEDLDFFRDFASQTSAYFQTRISDELNYFVEGSSLADKAVASIRGIVEIEQTQRDRRLEQQNQQLQDQIQAVGVGIAAGAIVASTSGLLFEEPIASPWAENRGEQLHPFAIALLASFGCAIVAWGVTKWVMGWKPKE
>NC_019693.1|WP_044197323.1|4297838_4298243_-|hypothetical-protein
MKDSTETLVMFAQLLEAKPPILQPDALPQVQKLAADLEQLSDGDINQAAELIMTWMEQFPQAEKAIQKAREQNRKEVKKIPEPDPNQSYSLIPNVEIIEETERTVIITQAPKAEKISLFLYVKQTLNRWTQKNP
>NC_019693.1|WP_015149643.1|4301946_4302213_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MALTQIIPAGAVTIPPEIIDWLQLKPGNSINIAISPDGKVYLEPAPKPAQIDVRTLSGCLYNPERQPVSLAEMERAIAEGAGESMSKA
>NC_019693.1|WP_015149644.1|4302194_4302602_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MDVKGLDTNVIVRFLVRDDESQWLKADQYINQALDTDELCLINNIVLCEVVWVLRSRYKLSRQKLIAILENLLNTNFFIFENREAIEWAVDPIKSGNADFSDYLIVRINQIAGCDETASFDIKLGQLPEVKRLDS
>NC_019693.1|WP_015149645.1|4302863_4303154_+|DUF1778-domain-containing-protein
MSLSSPTPSTTIEIILPPDQKIILEKAAQIEGLSLSEYLLKIATERAEQSLLKSESITLSENDWERVTGALANPPEINAALKTAINRYQKHLVWLS
>NC_019693.1|WP_015149646.1|4303512_4304466_-|hypothetical-protein
MTRFIYDEFTKKYIQELLKQLGQTETSKTMASQRREIDIFFTPNPENIADASHLGLLGRLATTPAVFEPFSNPVKPKEICSCLVKLLDIKAEIERQAIREKRRITPAQSPRLWMMTPTASAAVLADFGATLDLENWMSGIYFLAKGLQSAIIVLHQLPLTPETLWLRILGTGKVQKQALQELYQLAPDNPTRETTLELLYNLRELLEARQNLAPEERELIMELSPLYLQRLQTVKEEGIQQGVQQGIQQGVQQGVQQGVQQGQRRLVESLLQVKFGAVDAELASIIEALISIPPLEQAQLILQLSREELLARFSRDF
>NC_019693.1|WP_015149647.1|4304462_4305092_-|Uma2-family-endonuclease
MIAVKSDEHISPEEYLERERHSPIKHEYLDGEVYAMAGTSKDHNIISLNLALLLRSGLKNSPCQTFIADIKVNIANQKYYFYPDLVVTCDEEDNSNPYAVTTPKVIIEVLSESTESFDRGKKFQCYRTLPSLQDYILVSSQEYIVEIFHRIEGDRWMLETYQGLSEIARIESLDLNIPLAEIYATLDLTPIENPDSGVGDKNPVSTNDQ
>NC_019693.1|WP_015149648.1|4305397_4305874_-|cupin-domain-containing-protein
MTEPQPLLLRAQQIEASLQTFSHPWNPQSEIIGAYLGRATGLKRTGVNLAKIPPNKESFVYHSHHREEEWIYILSGQGIAEIDGQEFEVYPGDFMAFPTPSVAHHLRNTSDADLIYLMGGENLEVEIADFPHLGKRMFRQGDSVDIFNLSDRESFGPL

Crispr_ID: NC_019693_37

• CRISPR_ID: NC_019693_37
• CRISPR_location: 4316507-4316581
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_37

Consensus_repeat	Method
CTGTAGCGGCGATTCGAGAATCGC	CRISPRCasFinder

spacers of NC_019693_37

>37.1|4316531|27|NC_019693|CRISPRCasFinder
CTGAAAAATTATCCGCAATCATTACAC

CRISPR arrays and Neighbor proteins around NC_019693_37

CRISPR arrays

The CRISPR arrays of NC_019693_37

>merge|NC_019693|37|4316507-4316581|CRISPRCasFinder
CTGTAGCGGCGATTCGAGAATCGCCTGAAAAATTATCCGCAATCATTACACCTGTAGAGGCGATTCGAGAATCGC

>NC_019693|37|37|4316507-4316581|CRISPRCasFinder
CTGTAGCGGCGATTCGAGAATCGC	CTGAAAAATTATCCGCAATCATTACAC
CTGTAGAGGCGATTCGAGAATCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015149649.1|4305990_4306893_+|phosphotransferase	unknown	unknown	gnl|CDD|270701
NC_019693.1|WP_015149653.1|4316756_4320029_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|315987
NC_019693.1|WP_015149657.1|4325365_4326103_+|4'-phosphopantetheinyl-transferase-superfamily-protein	unknown	unknown	gnl|CDD|225002
NC_019693.1|WP_015149658.1|4326157_4327927_+|hypothetical-protein	unknown	unknown	gnl|CDD|378931
NC_019693.1|WP_015149647.1|4304462_4305092_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_019693.1|WP_015149662.1|4331462_4333646_-|hypothetical-protein	unknown	unknown	gnl|CDD|236766
NC_019693.1|WP_015149646.1|4303512_4304466_-|hypothetical-protein	unknown	unknown	gnl|CDD|237372
NC_019693.1|WP_015149656.1|4324386_4325229_+|transglutaminase-family-protein	unknown	unknown	gnl|CDD|224224
NC_019693.1|WP_156824069.1|4330594_4331389_+|flagellar-motor-protein	unknown	unknown	gnl|CDD|224279
NC_019693.1|WP_015149644.1|4302194_4302602_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350250
NC_019693.1|WP_015149654.1|4320633_4323084_-|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173793
NC_019693.1|WP_015149648.1|4305397_4305874_-|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380353
NC_019693.1|WP_015149652.1|4315138_4315999_+|SMP-30/gluconolactonase/LRE-family-protein	unknown	unknown	gnl|CDD|369882
NC_019693.1|WP_015149660.1|4328892_4330479_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149659.1|4327992_4328592_+|recombination-protein-RecR	unknown	unknown	gnl|CDD|234616
NC_019693.1|WP_015149645.1|4302863_4303154_+|DUF1778-domain-containing-protein	unknown	unknown	gnl|CDD|370057
NC_019693.1|WP_015149643.1|4301946_4302213_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|198034
NC_019693.1|WP_015149650.1|4306963_4312696_-|alpha-2-macroglobulin-family-protein	unknown	unknown	gnl|CDD|225248
NC_019693.1|WP_015149651.1|4312961_4314731_-|penicillin-binding-protein-2	unknown	unknown	gnl|CDD|274573
NC_019693.1|WP_015149655.1|4323070_4324120_-|ATP-binding-protein	unknown	unknown	gnl|CDD|223540

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015149649.1|4305990_4306893_+|phosphotransferase	gnl|CDD|270701	cd05152, MPH2', Macrolide 2'-Phosphotransferase. MPH2' catalyzes the transfer of the gamma-phosphoryl group from ATP to the 2'-hydroxyl of macrolide antibiotics such as erythromycin, clarithromycin, and azithromycin, among others. Macrolides penetrate the bacterial cell and bind to ribosomes, where it interrupts protein elongation, leading ultimately to the demise of the bacterium. Phosphorylation of macrolides leads to their inactivation. Based on substrate specificity and amino acid sequence, MPH2' is divided into types I and II, encoded by mphA and mphB genes, respectively. MPH2'I inactivates 14-membered ring macrolides while MPH2'II inactivates both 14- and 16-membered ring macrolides. Enzymatic inactivation of macrolides has been reported as a mechanism for bacterial resistance in clinical samples. MPH2' is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	7.97958e-125
NC_019693.1|WP_015149653.1|4316756_4320029_+|tetratricopeptide-repeat-protein	gnl|CDD|315987	pfam13424, TPR_12, Tetratricopeptide repeat.	3.17073e-17
NC_019693.1|WP_015149657.1|4325365_4326103_+|4'-phosphopantetheinyl-transferase-superfamily-protein	gnl|CDD|225002	COG2091, Sfp, Phosphopantetheinyl transferase [Coenzyme metabolism].	4.72345e-52
NC_019693.1|WP_015149658.1|4326157_4327927_+|hypothetical-protein	gnl|CDD|378931	pfam12708, Pectate_lyase_3, Pectate lyase superfamily protein. This family of proteins possesses a beta helical structure like Pectate lyase. This family is most closely related to glycosyl hydrolase family 28.	7.65335e-06
NC_019693.1|WP_015149647.1|4304462_4305092_-|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	8.54453e-37
NC_019693.1|WP_015149646.1|4303512_4304466_-|hypothetical-protein	gnl|CDD|237372	PRK13386, fliH, flagellar assembly protein H; Provisional.	9.55093e-05
NC_019693.1|WP_015149656.1|4324386_4325229_+|transglutaminase-family-protein	gnl|CDD|224224	COG1305, COG1305, Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism].	5.58786e-31
NC_019693.1|WP_015149662.1|4331462_4333646_-|hypothetical-protein	gnl|CDD|236766	PRK10811, rne, ribonuclease E; Reviewed.	5.23134e-06
NC_019693.1|WP_015149644.1|4302194_4302602_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350250	cd18683, PIN_VapC-like, Uncharacterized subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.30029e-39
NC_019693.1|WP_015149654.1|4320633_4323084_-|S8-family-serine-peptidase	gnl|CDD|173793	cd04847, Peptidases_S8_Subtilisin_like_2, Peptidase S8 family domain in Subtilisin-like proteins. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	1.96113e-75
NC_019693.1|WP_015149648.1|4305397_4305874_-|cupin-domain-containing-protein	gnl|CDD|380353	cd02224, cupin_SPO2919-like, Silicibacter pomeroyi SPO2919 and related proteins, uncharacterized sugar phosphate isomerase with a cupin domain. This family includes proteins similar to sugar phosphate isomerase SPO2919 from Silicibacter pomeroyi and Afe_0303 from Acidithiobacillus ferrooxidans, but are as yet uncharacterized. Structures of these proteins show a cupin fold with a conserved "jelly roll-like" beta-barrel fold that form a homodimer.	2.31976e-44
NC_019693.1|WP_015149652.1|4315138_4315999_+|SMP-30/gluconolactonase/LRE-family-protein	gnl|CDD|369882	pfam08450, SGL, SMP-30/Gluconolaconase/LRE-like region. This family describes a region that is found in proteins expressed by a variety of eukaryotic and prokaryotic species. These proteins include various enzymes, such as senescence marker protein 30 (SMP-30), gluconolactonase and luciferin-regenerating enzyme (LRE). SMP-30 is known to hydrolyze diisopropyl phosphorofluoridate in the liver, and has been noted as having sequence similarity, in the region described in this family, with PON1 and LRE.	2.7286e-86
NC_019693.1|WP_156824069.1|4330594_4331389_+|flagellar-motor-protein	gnl|CDD|224279	COG1360, MotB, Flagellar motor protein [Cell motility and secretion].	1.84361e-07
NC_019693.1|WP_015149659.1|4327992_4328592_+|recombination-protein-RecR	gnl|CDD|234616	PRK00076, recR, recombination protein RecR; Reviewed.	7.99812e-117
NC_019693.1|WP_015149645.1|4302863_4303154_+|DUF1778-domain-containing-protein	gnl|CDD|370057	pfam08681, DUF1778, Protein of unknown function (DUF1778). This is a family of uncharacterized proteins. The structure of one of the hypothetical proteins in this family has been solved and it forms a helix structure which may form interactions with DNA.	5.87707e-17
NC_019693.1|WP_015149643.1|4301946_4302213_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl|CDD|198034	smart00966, SpoVT_AbrB, SpoVT / AbrB like domain. This domain is found in AbrB from Bacillus subtilis. The product of the abrB gene is an ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. AbrB is thought to interact directly with the transcription initiation regions of genes under its control. AbrB contains a helix-turn-helix structure, but this domain ends before the helix-turn-helix begins. The product of the B. subtilis gene spoVT is another member of this family and is also a transcriptional regulator. DNA-binding activity in this AbrB homologue requires hexamerisation. Another family member has been isolated from the Sulfolobus solfataricus and has been identified as a homologue of bacterial repressor-like proteins. The Escherichia coli family member SohA or Prl1F appears to be bifunctional and is able to regulate its own expression as well as relieve the export block imposed by high-level synthesis of beta-galactosidase hybrid proteins.	0.000708745
NC_019693.1|WP_015149650.1|4306963_4312696_-|alpha-2-macroglobulin-family-protein	gnl|CDD|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0
NC_019693.1|WP_015149651.1|4312961_4314731_-|penicillin-binding-protein-2	gnl|CDD|274573	TIGR03423, pbp2_mrdA, penicillin-binding protein 2. Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NC_019693.1|WP_015149655.1|4323070_4324120_-|ATP-binding-protein	gnl|CDD|223540	COG0464, SpoVK, ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones].	6.36074e-37

Protein sequences

>NC_019693.1|WP_015149652.1|4315138_4315999_+|SMP-30/gluconolactonase/LRE-family-protein
MKTPKIIADYHCHNAEVPTWHPMEKRLYWSDIPTGRVFRYDPATTSHEQIYAGDSVGAIAVHEDGSLLFFMNKGAIARWQNDTLTPIIPEIPAERETRFNDCIVDPAGRVFSGTMEKGDHLGSLYRLNTDGTLTQVLEHLQIPNGMGFTLDRKHFYLTDSPKREIYIFDYDVSTGDISNRQVAITTPEGEGVPDGMTVDAEGYIWSARWDGHHLFRYSPDGKEVLRIPFPPKKVSALTFGGEDYTDIYATTAGGDNRAEEGEGAGAVFHLNLGIRGMPEFLAKIAV
>NC_019693.1|WP_015149651.1|4312961_4314731_-|penicillin-binding-protein-2
MVTGQTSFFSKVSTNKTDTKRSPIRPFVMMSIVTLLLGVCGVRLAQLQIVEGEEYRERAEDNRIRLIPIPAARGNLVDRKGKLMAANRLARAVYLWPREQQPEQWKETAKKLGPLIDVSPEDIVNKINETGYASGMPVRIAQRIDPAAFVTIAEAMADIPGIEVRAESSRYYPEGNTGAHVLGYIGEATQEDLMANPDYPMGIIIGKMGIEKTINPQLTGVWGNRLVEVNANGEEIRELGVRSAISGEPLQLTLDADVQKAAERALGSRRGAVVVLDVKTGGVIAMASGPSFDPNIFTRNVRAAEWQRLQELENPFLNRALQGYPPGSTFKMVTAAAGIGTGKYHPDSYLGTSSYIVVGGIAFHEHSGGYGVIGFRDALAYSSNTFFYQVGMEVGPEAIAQWGGKLGIGESTSLDLLGLDGGTHGMIPTPEEKLRMYNEPWYAGDSVTMGIGQGMVLCTPLELAVMSAAFANGGNRVKPHFLASQSNTPLTKPEPVGLSPEAVSVIKQGMVDVVQKGTGRVLNDGTVPLSGGKTGTSEVLGQPSHALFVGFAPAVNPEISIAVVVENGGYGGVAAAPVALEVYRTYFKK
>NC_019693.1|WP_015149650.1|4306963_4312696_-|alpha-2-macroglobulin-family-protein
MRLIRRTWTWFILGLLLSFTIAACNFFQTASTLKQLPAVAPLAMPELPEWIEEISPTGEADPLAQIRIRFTDPVIPLESLDSPEQTAKLNQFQITPELPGEFRFLTPRMVGFQPDEALPKATRIQITLKAGLADLNNHQLSQDLAWTFNTEPLKLTNLPTSDPADEYSEPQWIDLKQPLEFTSNVPLNLNSLKQHVKLVPVGRNEGVSLQVDSLDSEEALTASSVLAFDPSLQTWDYQITPQQELEKGTEYRVEITPGLEPARGNLVSQHSFTSQVKTYEALQFQEMELYGKPEFGFAYGRFLNGAPQLTFNNVIDPESVENQITINPPPKSEPKLIQAHANSNEIRLNPWALEPATQYTINIGSDVQDKYGQKLGQPITLNYQTGDLAAEIWAPSDLNVFPSSKDLELTLSAVNLPNSAYKAAYRIVEPTDLVFTDSAYPRGNGTDLLPDPNNWQSFPISSPPKNQTATVAIPLRERLGGTTGLLAYGIQGRTNSYQENGQQKWSEPTSYGLVQLTNLGVFAQWFPDTGLVKVNHLSDGSAVGNARVEIYQSQTNATTRSPVTPCTTGTTNATGLLVLNSQQVQRCRQSAEEAPELLAVARENQDWAYTRIWSYSGAYGYGIDGEWNAGGPLSRGTIFSDRQLYKPGETAEFTAVAYYQENGDLIQHKNAAYTVTLRDPEGNETALGTQTTNEFGTFSLEVPLGSDLPLGYYSLVAKSNNNVELNGEFRIAEFKPPNFQVQLNLDKTYALSNEKIQAKAESNYLFGSPVAGGNAKYYITRSPEEFTPPGWTEFSFGRQWFWPEEQPELSSEVLQQTARLDNSGFNTLNFTIDRDLPYPMTYRIDAEVTDISNLSVANSQTLTALPSDKLIGVKTNFVADAGKPFSIEAIVTDPSGTAINGQTLRVELQKMDYSSVTRVVEGSRTPRYQVDYETVATETLKTGNTPKTVSITPPEAGSYRIRVNLANAKTDATATDVQIWATGTRGVSWGRRSDRENFLEVKLDKDTYQPGEIATALIQSPYPEAELYFAVVRDQPLYQTITKVSGGAPQIQFKVTPEMLPNAAVEAVLIRQGPPLDQVEPANVEDLVKIGFAPFKTDLGEKYLTVQVTPTQATVQPGTQETVQLQVTDSQNRPVQGQLTLMVVNEAVLQLTGYRPPNLVDTVYAEQPISTRWSDNRFDVVLSPLSSPLQKGWGYGGGFSAGSGSTEIRTEFKPLAYYNGSVMSDRNGRATVSFPLPDDLTTWRVMAVATTTDMRFGNGDNTFISSKPLMATPLLPQFVRPGDRFSGGLALTNTTGEKGRLQIQGAVSENLYFADDTTTSQSFQTEAASGTRAYRFPMQASTLGEGTVRFVSQLNRQGDAFEVPLSVKQLSVSETVVETGTTENQANIPLNIDNNVLPNVGGLQIDLASTLIPEITAPARDTFAEDSLPFLEPAASQLSVAANLQILGQKYPQALGEFNPPEQAAIALDLLQKLQQPDGGFAAYPGQTQSDPFLTAYAAESLSQGRTAGFAVDEAMVSRLRGYLQKTLADPGQYSYCTSQSCKNRVRLGALMALSELGERRNDFLADIYAQRNDLDAVAQTKLARYLGQFPEWQTEAQSLSNQRFETVAETGRSATVNLPQGWGWLSSATTAQAQTLRLAIAKEANPTVRSRLLQGLLNQRREGTWENSYANAEALSALVAYSNSQPTPPNFTATANLGGNTLDSMQFQGYENSRQFIQVAMDSLPKGQTNLTLNKTGNGTLHYLVEYGYRLPGNQPGRYNGLRVQRNISPVGGDKAIAQFGLAKPDKNLVVDAGQVFDIGLEIISDRPVDHVVITDPLPAGFEAVDSSFQTTTSAVKSAQSSWEIGYQNLYSDRIVAYADRLQPGVYTLHYLVRSVTPGIYEWPGAHVHLQYAPEEFGRSASSSLEVKE
>NC_019693.1|WP_015149649.1|4305990_4306893_+|phosphotransferase
MTRSPDAIVTLANRHGLAIDPASLQTDESGLDFQVAIAQTPDRASWLLRIPRRPDVLDSTQRERTILTLVRPYLPVQVPDWQIHTDELIAYPLLTGKPAGTIDLEIQNYRWEIDAENLPEVYLQSLADALVALHGIEHQAVTKAGLETPSIPGIRTAWLERMARVKGVYPVNPDLWDRWQRWLDRDILWPAHTTLIHGDLHPGHILVDRQGQVTGLIDWTEARVDDGTLDFAAHYQVFGRVSLDALIHQYEQRGGTIWATLGDHVVEYHSAFGVQVAEFAERSGLDEYKGMARQMLSQSP
>NC_019693.1|WP_015149648.1|4305397_4305874_-|cupin-domain-containing-protein
MTEPQPLLLRAQQIEASLQTFSHPWNPQSEIIGAYLGRATGLKRTGVNLAKIPPNKESFVYHSHHREEEWIYILSGQGIAEIDGQEFEVYPGDFMAFPTPSVAHHLRNTSDADLIYLMGGENLEVEIADFPHLGKRMFRQGDSVDIFNLSDRESFGPL
>NC_019693.1|WP_015149647.1|4304462_4305092_-|Uma2-family-endonuclease
MIAVKSDEHISPEEYLERERHSPIKHEYLDGEVYAMAGTSKDHNIISLNLALLLRSGLKNSPCQTFIADIKVNIANQKYYFYPDLVVTCDEEDNSNPYAVTTPKVIIEVLSESTESFDRGKKFQCYRTLPSLQDYILVSSQEYIVEIFHRIEGDRWMLETYQGLSEIARIESLDLNIPLAEIYATLDLTPIENPDSGVGDKNPVSTNDQ
>NC_019693.1|WP_015149646.1|4303512_4304466_-|hypothetical-protein
MTRFIYDEFTKKYIQELLKQLGQTETSKTMASQRREIDIFFTPNPENIADASHLGLLGRLATTPAVFEPFSNPVKPKEICSCLVKLLDIKAEIERQAIREKRRITPAQSPRLWMMTPTASAAVLADFGATLDLENWMSGIYFLAKGLQSAIIVLHQLPLTPETLWLRILGTGKVQKQALQELYQLAPDNPTRETTLELLYNLRELLEARQNLAPEERELIMELSPLYLQRLQTVKEEGIQQGVQQGIQQGVQQGVQQGVQQGQRRLVESLLQVKFGAVDAELASIIEALISIPPLEQAQLILQLSREELLARFSRDF
>NC_019693.1|WP_015149645.1|4302863_4303154_+|DUF1778-domain-containing-protein
MSLSSPTPSTTIEIILPPDQKIILEKAAQIEGLSLSEYLLKIATERAEQSLLKSESITLSENDWERVTGALANPPEINAALKTAINRYQKHLVWLS
>NC_019693.1|WP_015149644.1|4302194_4302602_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MDVKGLDTNVIVRFLVRDDESQWLKADQYINQALDTDELCLINNIVLCEVVWVLRSRYKLSRQKLIAILENLLNTNFFIFENREAIEWAVDPIKSGNADFSDYLIVRINQIAGCDETASFDIKLGQLPEVKRLDS
>NC_019693.1|WP_015149643.1|4301946_4302213_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MALTQIIPAGAVTIPPEIIDWLQLKPGNSINIAISPDGKVYLEPAPKPAQIDVRTLSGCLYNPERQPVSLAEMERAIAEGAGESMSKA
>NC_019693.1|WP_015149653.1|4316756_4320029_+|tetratricopeptide-repeat-protein
MATSPLPPDVVIPRQQYLQAVQQGLSRLGSQPQNLLVFYGSDRLRWGLGKAIAQQLKPQIPCIYIDGMEIRRRNPATDEQALSELRYQLRAGKEYFTSFDFAFTCYKSLTKSYQNITPANYAKGMDRADRLSTGADLVSAFAGIDLEKLSQQIGLPEVGATMQQLLPYFWDDLQEIGRNSMPLITFLLKLNWFFLKNVDAWRWWEEIGCRELQPLKDCVSPYQIVEYLPKLLARGLQQYLDCLKKPLVILIDDYEALADPSEWLETLISEPNPWVLWVVVARRLPQWMEASERIPILPLTEAESQEVLTTAGISGDRLLSTITEICQGTPYYMHLCVKRWQKIQQRRSPQVEDFAGKPEEFLTTEAATWDPGELRMLQVLAIPREWDAARFDRLMQQQHLETWRGRFAEVIASPYIEEVAEGKWRLNPLMRQYLLETQPTTQRQTLHQELYEELRQEYLQAQTPQAAILALDQALDHAIDSSHSSEATAWVLAQMPIHQQQSQHSEVVEMLRSLLKRLGEPITATTAKAQMLLGYSLVELGETEKALKELETAKAQYAAVGLGDSLEAARVEYELAGVYLACDRTFDAKNAAMRSRQLRQQQLGKDAPEVAEVLNRLAAIASDCGEYREAVLYCDRALDILNSQPQPHPIQLASVKKTAALLKIYNNQLDDAAQLCKEARQLAIEVGGENHAIAIQSLMMLGGIHSRMGPRLYPKSLEEYQKALTAAEEVFGPSHFQTLDVLEAMAELCRKMGQHQAADEYAERHNAYVKVGESAVTPELARRLSILGGELYKKGEYGKAEPLWKQALNIHRKVLGEQHPDTAGSLNNLAALYKSQGRYAEAESLYLQALNIRRKVLGDEHPDTALSLHNLATLYYSQGRYAEVEPLLLQALDIYRKVLRNEHPHTASSLNSLALLYYSQGRYAEVEPLLLQALDIYRKVLGNEHPDTASSLNSLAGLYDSQGRYDEAEPLFLQALNIRRKILGNEHPDTALSLHNLAGLYDSQGRYAEAESLLLQALDIYRKVLGNEHPDTASSLYSLAGLYYFQERYAEAEPLLLQALNIYRKVLGDEHPHTKTTAENLQMLQDKRNS
>NC_019693.1|WP_015149654.1|4320633_4323084_-|S8-family-serine-peptidase
MENYEHLQLRKVESQLPRRKSKPGGFGGEKRGDRRSHGSQLLTQVEVLSQKFEEKHRPFGINPKLIFKIKLRENDSLETHLPSLGLNLLEKAPKVHQAIVVFADDNHLAELEKRLKSYAGLIPKGYEYAYLDDIEELVPLEPEDRIGLLLKLDPLKPGEVVPLDMELWHTGNVKELNSYINEVDEFLRDIGPQLGLKVSDRYIGKYICNLRIQVNSDILEILLQEYQVKEIDRRPQPAFESPLEYNIPLSSLPEIPSPELESTGILVIDSGVQRGHPLIAPALGESEVFPDSKYQFITGGPDDGDIKTGGHGTGVAGIALYGDVAECVKNNSFQPQVWLFSARVTNENNEYDPDSLLDKQIEEAIDYFVRNYKNCKVINISLGDSRLIYQQGEKQFRLAARIDEIAYKFQHQNILFVISAGNFWYESDSAELIARDYPHYLLSEDAQIIEPATAAIALTVGSLSQGKGSGLYPGDARRRAITKVEKYPSSFTRTGFGVDGMIKPELVEFGGDLILDGDRLSNNDWGNAMITLNKNFQGSSLFKFYRGTSFSAPRVANLAAKLFTQFPDATSNLIRALIADSAKIPTDIPPLFEGELSEQKNNRLKIYGYGQPDFTRAAYSQKHQVLLLVDHETLNLGHYQIYEIPLLPEEFIKSKGTKTLSVTLAFDPPTRHTRGDSYLGITMEFYLFRNIEPDNLNKAFFDKGKKPENSEDFMAISIGELKEKHGNNIEIELKPGRELRNKGTLQKGKLSFSKANWKYDYKPLYLVVACKKKWVNPDEISSQRYAIVASISHSNESVDLYNKLRGEIRLTPRIRG
>NC_019693.1|WP_015149655.1|4323070_4324120_-|ATP-binding-protein
MATRGDLIRKLFKSFSENDREEFYAAAQELIQEERNKNHLLLAKELEKSLQLTSPVKSIASNGSRWQTYPEVPKAKDTGLPLITVKTYDLTWENVILTDKNREILETVVLENRKQEILTAYNLKPRSTLLFCGPPGCGKTLTAQVLASVLSLPLVYVNLSAVFSSYLGETAINLNLIFEYIHKGQWVVLFDEFDAIGKDRNAANDHGEIKRIVNSLLQLIDSRNHASLFVAATNHSSMLDSAIWRRFDEVLLFDKPSHDAIISLLLKNLGSIRHEIDVYPLADQLKGATGADIERICQNAIKSVILKGEKVLKPEDLEAAIAHHHDRMEVVTRSQNSQEFVTGDANGEL
>NC_019693.1|WP_015149656.1|4324386_4325229_+|transglutaminase-family-protein
MKFKLGCTLNYNVESLSTFVFNIRVVETDCQKILTEQLIIDPDIRIDEYVTPIVENRYFRVNVPGGTNLNIFYQATVEMNHFYGDANTIAEVQPADLPVETFHYLYPSRYCESDRLHQLALSEFGELTTGYSRVTAICNWIYEKVIYEYGTSNPHTSAFDTATERIGVCRDFAHLAIAYCRALNIPARCVAGYAYGLNPPDFHACFEAYLGGRWYLFDATRLAPQNGIVRIGTGRDASDVAFATIFGDILLNKMDIFMEHIPEGNSSEVPELTTEAISIS
>NC_019693.1|WP_015149657.1|4325365_4326103_+|4'-phosphopantetheinyl-transferase-superfamily-protein
MNIEWKPSPKIIKLSPQQVHVWRVELDRNSTEIRQFRAMLSEEEQKRADRFHFEHDRHRFIVGRGRLRSLLARYLQVAPEEIEFRYSAKGKPMLANVEQGLHFNLSHSGGLALYAIASQPVGIDLEQIRDLSDAEQLAKRFFTPAEAEAIAALPMAQKQAAFLNAWTRKEAYLKATGDGLAGLDEVEVSLIPGMPAKLVAIQGNSELASNWFIGELHPHPDYVAAVAIAGQDWQVCYFKDERGNP
>NC_019693.1|WP_015149658.1|4326157_4327927_+|hypothetical-protein
MNQPPNRLSPRWKKFWQFVCLAGCALSLILGGYAISNYNQNLSNSLDNSPPILPNSVAVNSVNSPEAVTVTSQAATPRNSRILASNCGSPQGGPTDNPIAEQYSNSSYPWTNQIKWNCVYNIEDFDGGTMVARFNAARDAAAANGGGVVYFPAGTYSFEDSISLKNGVVLRGEIPSVTDAKKSEFNPPSKLQFPKYEPQFSGDGTPNDTAFKTITTTAGDTDSNIGLVHLDINRTAISLRGDLDNGNNQNLVIFGIRSNNVAEPDPRVPDTSFQNPWLRYSYRFAANIKVNAKANILIANNRINDNITDNYDQPGYQVKPIKGEEIITYQEGNKVPFHYGNHYGIVVNRAKSEGFQKNANPQTEPGLFRPGITVRDNWVYHTMRVAISASGDGLVIQDNQVRDERGKQWWTDPTGLKEPRGAVTLENRAIDWSGSNVLVEGNQYEVYRHRIRDTQYLSVDGEGILIQECCGGTEVNGAIIRNNQGNTYIGLYKIPSIKKVEIIGNQVNNELTDIELIYVNADTNNAPGVMEDVTIANNIVNGGILAKGTAGGKRNTVENNQGNNSAALTYSCHVAAKGNTGFQEPPCLP
>NC_019693.1|WP_015149659.1|4327992_4328592_+|recombination-protein-RecR
MTVYTRPLARLIEQLQRLPGIGPKSAQRLALHLLKRPDDEIQALAKALVDAKQQVGFCKECFHLSAEPICEICRAPNRDRDVICVVSDSRDLIALEKTREFRGKYHVLGGVISPMDGIGPEQLNIQALVRRVSQQQIKEVIIAISPSVEGETTTLYVGQLLKPFTRVTRIAFGLPMGGDLEYADEVTLARALEGRRDLD
>NC_019693.1|WP_015149660.1|4328892_4330479_+|hypothetical-protein
MSQFLSPVKGPLVLGLIDQFNSVLLPPYLLGFVLSLIVLTFITIFLRWGVYQHLIYLASRVRGLIYDPNPTKKPRIVEEIEIRCKESSPALEHMNTGALIDQVYSRHLLKNEQIDYFCRFLPNLLLSLGLLGTFLGITMNLAELSQTINDFGVGSIDALVEQVQRPLQGMGVAFISSLTAVACSALLTVVNLLRNTSIAKYQLISALEDYIDNIYGPALNRRSPLDKAVDRLETLFGTFVSQFSVSVKEAVSSSLGESVDQITEGNRQANHLASQVYNRLMESSSSMMSGATMFRESAQIFEKSQFANKLASSTDNLANTQRDLARSSSVLNQSTQALQLAIASLQTTSQETIHLSEEIAGLSKNSGQVLNLTQNNQTALSEVVGEMQQSAQIFHSVIKTLDTLQKRLATRTDRFVDVHTELYKLVESLKLFTEEMKGGMQTLGDRLVASLGDRNGINPAADPVATRISKLGNDLTAVQSQLTQVVKHLESEEQTGIAPTRLSHPPAAHSNDPFNPKLVNWEEEDNPE
>NC_019693.1|WP_156824069.1|4330594_4331389_+|flagellar-motor-protein
MPPEFDIWPAFTDLMSNAFMILSFLLLLAIIKPLVSISTMRETEEALRQQLLRTQIDLTSAQNRATLAESQVAPLVAQNQALAAQTQTLQGQLQQEMATPKAPPIIVIRDTGAYQFSSGSAQLPDALQTYVRNQLVPQIEANAAAYNINVIEIIGHTDGQPNNAGSSNLDRSLPQVAAGTTPVNQLVPGSNADLGLMRALAVVQILQTIQGTEGKLQGLQFRPYSAAQLVSPTGNFGNVNPNPDESRRRIEIRFTRLGEETSVQ
>NC_019693.1|WP_015149662.1|4331462_4333646_-|hypothetical-protein
MSYSLPKNSLIDLLSQPTVVAVLASVGIHGLVGISWDRLPFSGGNEPNPWTTVDLVNLSPEELSRLPDFSSPQATGSGSLNSSSEPLAGLPELGPVPPSPGRLGLEPLTLPPGTPLYDLPLDLPPAPSFRDLPTPLPSLQDYQSPSSFREGLTNRQSSGSSNSMAIEQLLALERLERAQMEREIEQRERQQRLNAEQNRLTPPPPPQEFRLQDVPPTPQGSFPPSGDQQRPLSGMNEAVDSSEFEDIPIPENVPGPEAIARSDNANPSPPPGFSQSGTLPGDVDPGMGPNATRPESDQMGSAADLQTDGRNVQQDGIEEGAQAVVPSTVPTQGDRPQEGAAVPDQIGTDEDSVRELWARILEPNRDNPTGLVSDRQNDQLEGIQAYVQWLANLESEYGEVRTNTPISVNQYPEDACPQQLEGRALFGVLVNPDGQIIDGPRRLLGSGQDILDSFARKFVQDMDFAGVSEPTVHQYAFEFQYDPQLCSNPPSPGTNPTPPVETRQPELNNPQPTGENATPVLDAESPGEENSTPVLDAESPGENSTPVLDAESPGEENATPVLDAQPPRENSPLRVEQAPASRPQQLRDPSPEEEPSKPVNVAPPAKPAPGPVPGETRQEAVEPEAVQESVPEQVQPQNEAIPPVETPEMGEEEGLTPDGLESTPTEDSQELPTPEASEAEGAEVVEGDNLESEPESEAESEEEEDAAEMEGESEEAIADEEESDPEI

Crispr_ID: NC_019693_38

• CRISPR_ID: NC_019693_38
• CRISPR_location: 4355452-4355563
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_38

Consensus_repeat	Method
CCCCCCCAGCCCCCTTCCCTTCAAGGGAAGGGGGAGAAAGA	CRISPRCasFinder

spacers of NC_019693_38

>38.1|4355493|30|NC_019693|CRISPRCasFinder
TTTTTATTCTCTTTTGAAAAGAGACCTAAC

CRISPR arrays and Neighbor proteins around NC_019693_38

CRISPR arrays

The CRISPR arrays of NC_019693_38

>merge|NC_019693|38|4355452-4355563|CRISPRCasFinder
CCCCCCCAGCCCCCTTCCCTTCAAGGGAAGGGGGAGAAAGATTTTTATTCTCTTTTGAAAAGAGACCTAACCCCCCCCAGCCCCCTTCCCTTCAAGGGAAGGGGGAGTAAGA

>NC_019693|38|38|4355452-4355563|CRISPRCasFinder
CCCCCCCAGCCCCCTTCCCTTCAAGGGAAGGGGGAGAAAGA	TTTTTATTCTCTTTTGAAAAGAGACCTAAC
CCCCCCCAGCCCCCTTCCCTTCAAGGGAAGGGGGAGTAAGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015149684.1|4357524_4361274_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|274362
NC_019693.1|WP_015149682.1|4354794_4355409_+|DUF4440-domain-containing-protein	unknown	unknown	gnl|CDD|379209
NC_019693.1|WP_015149676.1|4348911_4349376_+|Holliday-junction-resolvase-RuvX	unknown	unknown	gnl|CDD|234639
NC_019693.1|WP_015149681.1|4353306_4354605_+|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl|CDD|178100
NC_019693.1|WP_015149673.1|4344843_4345782_-|carotenoid-biosynthesis-protein	unknown	unknown	gnl|CDD|367884
NC_019693.1|WP_015149688.1|4375311_4377216_-|response-regulator	unknown	unknown	gnl|CDD|223816
NC_019693.1|WP_015149683.1|4356376_4357528_-|response-regulator	unknown	unknown	gnl|CDD|226702
NC_019693.1|WP_015149677.1|4349554_4349812_-|nucleoid-DNA-binding-protein	unknown	unknown	gnl|CDD|223847
NC_019693.1|WP_015149675.1|4347561_4348809_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379228
NC_019693.1|WP_156823874.1|4378653_4378854_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149686.1|4371400_4371778_-|response-regulator	unknown	unknown	gnl|CDD|381104
NC_019693.1|WP_156823875.1|4378869_4379013_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149689.1|4377472_4378093_+|hypothetical-protein	unknown	unknown	gnl|CDD|368243
NC_019693.1|WP_015149685.1|4361500_4370281_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|226415
NC_019693.1|WP_015149678.1|4349935_4351210_+|MFS-transporter	unknown	unknown	gnl|CDD|340887
NC_019693.1|WP_015149674.1|4346190_4347384_+|F420-0--gamma-glutamyl-ligase	unknown	unknown	unknown
NC_019693.1|WP_044195348.1|4351489_4352140_-|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase-HisIE	unknown	unknown	gnl|CDD|235067
NC_019693.1|WP_015149687.1|4372546_4375315_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|274368
NC_019693.1|WP_015149680.1|4352145_4353018_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149691.1|4378973_4380458_-|glutamate-synthase-subunit-beta	unknown	unknown	gnl|CDD|237213

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015149684.1|4357524_4361274_-|PAS-domain-S-box-protein	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	3.76395e-85
NC_019693.1|WP_015149682.1|4354794_4355409_+|DUF4440-domain-containing-protein	gnl|CDD|379209	pfam13474, SnoaL_3, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	2.84906e-05
NC_019693.1|WP_015149676.1|4348911_4349376_+|Holliday-junction-resolvase-RuvX	gnl|CDD|234639	PRK00109, PRK00109, Holliday junction resolvase RuvX.	9.54799e-55
NC_019693.1|WP_015149681.1|4353306_4354605_+|glutamate-1-semialdehyde-2,1-aminomutase	gnl|CDD|178100	PLN02482, PLN02482, glutamate-1-semialdehyde 2,1-aminomutase.	0
NC_019693.1|WP_015149673.1|4344843_4345782_-|carotenoid-biosynthesis-protein	gnl|CDD|367884	pfam04240, Caroten_synth, Carotenoid biosynthesis protein. The representative member of this family is CruF, a C50 carotenoid 2',3'-hydratase involved in the synthesis of the C50 carotenoid bacterioruberin in the halophilic archaeon Haloarcula japonica.	7.11643e-85
NC_019693.1|WP_015149688.1|4375311_4377216_-|response-regulator	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.44777e-80
NC_019693.1|WP_015149683.1|4356376_4357528_-|response-regulator	gnl|CDD|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	1.3719e-68
NC_019693.1|WP_015149677.1|4349554_4349812_-|nucleoid-DNA-binding-protein	gnl|CDD|223847	COG0776, HimA, Bacterial nucleoid DNA-binding protein [DNA replication, recombination, and repair].	2.18796e-12
NC_019693.1|WP_015149675.1|4347561_4348809_+|GNAT-family-N-acetyltransferase	gnl|CDD|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.51548e-09
NC_019693.1|WP_015149686.1|4371400_4371778_-|response-regulator	gnl|CDD|381104	cd17552, REC_RR468-like, phosphoacceptor receiver (REC) domain of Thermotoga maritima response regulator RR468 and similar domains. Thermotoga maritima RR468 (encoded by gene TM0468) is the cognate response regulator (RR) of the class I histidine kinase HK853 (product of gene TM0853). HK853/RR468 comprise a two-component system (TCS) that couples environmental stimuli to adaptive responses. This subfamily also includes Fremyella diplosiphon complementary adaptation response regulator homolog RcaF, a small RR that is involved in four-step phosphorelays of the complementary chromatic adaptation (CCA) system that occurs in many cyanobacteria. Both RR468 and RcaF are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.2225e-55
NC_019693.1|WP_015149691.1|4378973_4380458_-|glutamate-synthase-subunit-beta	gnl|CDD|237213	PRK12810, gltD, glutamate synthase subunit beta; Reviewed.	0
NC_019693.1|WP_015149689.1|4377472_4378093_+|hypothetical-protein	gnl|CDD|368243	pfam05019, Coq4, Coenzyme Q (ubiquinone) biosynthesis protein Coq4. Coq4p was shown to peripherally associate with the matrix face of the mitochondrial inner membrane. The putative mitochondrial- targeting sequence present at the amino-terminus of the polypeptide efficiently imported it to mitochondria. The function of Coq4p is unknown, although its presence is required to maintain a steady-state level of Coq7p, another component of the Q biosynthetic pathway. The overall structure of Coq4 is alpha helical and shows resemblance to haemoglobin/myoglobin (information from TOPSAN).	5.23493e-22
NC_019693.1|WP_015149685.1|4361500_4370281_-|PAS-domain-S-box-protein	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	0
NC_019693.1|WP_015149678.1|4349935_4351210_+|MFS-transporter	gnl|CDD|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.18581e-57
NC_019693.1|WP_044195348.1|4351489_4352140_-|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase-HisIE	gnl|CDD|235067	PRK02759, PRK02759, bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE.	2.7548e-128
NC_019693.1|WP_015149687.1|4372546_4375315_-|PAS-domain-S-box-protein	gnl|CDD|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	1.52029e-65

Protein sequences

>NC_019693.1|WP_015149682.1|4354794_4355409_+|DUF4440-domain-containing-protein
MKTQQQPHQFRGSPLFWTALLALPIAFTLPESAVGQVNEQELQSILQTRQIALDALNNRDFTSIEPYLHPAFTITTVDNKVFHTVSEFEAYWNEQFTGPIERLTMSLEGETIRTFLSPEIEVASGEALSTFYFRDGNEEMMPLRWTAVLQKVQNTWTIQSLHFSANLLDNPVLNHAENRGNFMAVGTSVAGVLVGALLMFLLRR
>NC_019693.1|WP_015149681.1|4353306_4354605_+|glutamate-1-semialdehyde-2,1-aminomutase
MVTTTFNTTKSEEIFAAAQKLMPGGVSSPVRAFKSVGGQPIVFDRVEGAYVWDVDGNQYIDYVGTWGPAICGHTHPEVIAALHDALNKGTSFGAPCYQENVLAEMVIDAVPCIEMVRFVNSGTEACMAVLRLMRAFTGREKLIKFEGCYHGHADMFLVKAGSGVATLGLPDSPGVPKSTTANTLTAPYNDLEAVKTLFEQNPDEIAGVILEPVVGNAGFIPPDAGFLEGLRVLTQEYGALLVFDEVMTGFRIAYGGAQEKFGVTPDLTTLGKVIGGGLPVGAYGGRRDIMEMVAPAGPMYQAGTLSGNPLAMTAGIKTLELLNKSGTYEYLDKITKKLSQGLLKIAKETGNEACGGQISAMFGLFFNPGPVHNYEDAKKSDLSKFARFHRGMLERGVYLAPSQFEAGFTSLAHTDEDIDRTLAMAHEVMSSL
>NC_019693.1|WP_015149680.1|4352145_4353018_-|hypothetical-protein
MRVLVTIPHVFNPEGGGGYASLSPDSQPRIQALTQCIESLHHCYNRASQFYFQYNQQLYTLPANLETSVELSIIICTTQGLHLLDQLPVSRDSYTHKSFACHPMLLGFECHGVLKQNLGRYDYYCYLEDDIILSDPDFFQKLSWFTGYIGNHAVLQPNRFERLNKPGVRKFYIDPELEFKTGRKDNFAHYFSDNLVLTGKVLGQPITIKRAENPHSGCFFLHRPQMEQWANQPYFLDRDSRFFGPLESAATLGIARTFRVYKPAPQNANFLEVQHYGEGWSQKIKDVKFT
>NC_019693.1|WP_044195348.1|4351489_4352140_-|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase-HisIE
MSETEMASSKTAIPVDRIRYNEQGLVPAIAQDYLDGTVLMMAWMNAESLQKTLDTGECWYWSRSRQELWHKGATSGHLQKVRSLRYDCDNDCLLIGIEQIGDIACHTGERSCFHQIEGHIAAPPADTLSQVFEVICDRRDHPSEESYTARLIAGGDNKILKKIGEESAEVVMACKDDDADAIAGEVADLFYHSMVALAKHNVDLREVYRKLQQRRR
>NC_019693.1|WP_015149678.1|4349935_4351210_+|MFS-transporter
MKRLFNRLLDWLPKLPLQVWVLISGRLLSGIGSGFTLFYAPIFFVNEVGLTKTAVGFALGIGSIAGIVGRIVCGSCLDSPHWGRKRTLLAAAIISAIASGVLTVANGFEILVLGNILMGFGIGLYWPATESVVADLTTGGQRHEAYAMARLGDSLGLQVGVIWGGFLISVTGEYRLLFIIDSASFLLFFGLIWMAITEPQRQGGASKPPLQGWMSAFRDRTLMVYALVNIIFTTYIAQIQTTLPLYLSDFVESEDTGRGFSPGTIGGLFTWHLALCILMQLPVSRVFKDLRQSKVLAISGILWAAGFIFIAITGTISTSPLVTATIALGILAIAIVVYNPAASSLVAEMAPVSLRGVYLSLNSQCWAIGYFIGPLLGGWVLDLPRPLSDGLWPGLVVSVGIVIGILQVLDRMLIQRKRLSESQV
>NC_019693.1|WP_015149677.1|4349554_4349812_-|nucleoid-DNA-binding-protein
MSIDKTELIAKIAQRVQKQPEAVEEILDATLVEIYESLKQGQSVSLKNFGTFYIRPEGETSVFKFNPSQRLRKLFGWASTYRGEL
>NC_019693.1|WP_015149676.1|4348911_4349376_+|Holliday-junction-resolvase-RuvX
MTQKISALGLDIGRKRIGVAGCDGTGLIATGITTIESKSFADTLSQLQAIIEERGVSLLVVGLPYSMDGSIGFQARQVQKFSKRLSAALHLPIEFVDERLTSYYAEQMMIDQNLSPSRNKGLIDRKAAALILQQWLEDRRKTIKTETTEQSNEG
>NC_019693.1|WP_015149675.1|4347561_4348809_+|GNAT-family-N-acetyltransferase
MTSHLPQNQTLTIRPLQYRDLETVAELANATEIEAGSPSSSIDNGSLDIGTQIDRVRRWYWPLKLLSVFPNPLQNRLCVRVAQDDRKIRGAIQISPFNHTRSTWRVDRIVVPPSSEKLGIGSQLIRHCLESIWEARMWLLEVDVNEKDELALYRHNGFQPLAQMTYWAIAPELLEQLAQREPDLPNLMPVSNADAQLLYQLDTAAMPPLVRQVFDRHIQDFHTSLVGAVVQGIRQWLHKTETVSGYVFEPQRKAAIGYFQVRLSRNGSQPHVAELTVHPAYTWLYPELLAQMARIVQELPAQTLLLASADYQPEREEYLQQVGAQRISHSLLMSRSVWHKLRESKPVSLELQLSEVLQGLQGTRKPIPSRMSWLKKPPSPSTGGKQEPSQSSMEDIGSLLPSDQLDMTLEDDTLS
>NC_019693.1|WP_015149674.1|4346190_4347384_+|F420-0--gamma-glutamyl-ligase
MAIATTIGITLGAAALVLGTAAAAIEYQYRRRPGNQLDLTPGEWHEEVLSPERRHLIGELELINRTSTLEIMVPEVHTEVKLLSGSSLEGITTRAEVIPMHPDEKSRDDNYWFGYIVKIGKKTRMKVAVDIQGPNLDRLKAAWIAVTYVTYGPEGRIPKTRHVVVPFKYPDPSESSNWRKIPEADSEILPIKTHLLTNLDDPVDIVKRYVMPHAQPGDIVTIGETPVAIMQDRWHHPSTVKPGFVAKRLCYFFLPTSSLATACGLQTLVDIEGPVRVALAFFIGAIAKVFGKPGVFYQLAGEQARLIDDVTGTLPPYDQFIVLGPDNPQQVVDTIKQQTGLSAAIVDVNDLKAVKILAASSELSTDVLEQSLRSNPAGNADEQTPVVLIRPGRKSQS
>NC_019693.1|WP_015149673.1|4344843_4345782_-|carotenoid-biosynthesis-protein
MKQLVTAERLCLISHTLSMAFGLAGLLLVLPNPEFIVNLSEFGQKVFQWSMAGGGVSYIILGAVAVALYAYRELGTRLWLTFMVPAVVLSLGSELLGTSTGFPFGHYQYLSGLGYKIAGLVPFTIPLSWFYMGLVCYVLARAGLESIQLPNWVRQVGAIAVGALLLTAWDFVLDPAMSQTQFPFWQFQEEGAFFGMPYRNLTGWMGTGAIFMSVAAFFWGKAPIRLSRSQLGLPLITYIVNFAFGAIITLVALDSRFVIPTLLSMVLGVVPAVVLWWIASPLEAAETEEATAPIPANTLSQVSLPPVEVAAK
>NC_019693.1|WP_015149683.1|4356376_4357528_-|response-regulator
MIQLSAEFNKPVILIVDDQPDNLRVLSSMLMVKGYNVRKAITGKMALATCQKVVPDLILLDIMMPDLSGYEVCESLQSNPLTCQVPVIFLSALDDSTAKVKAFSSGGADYITKPFQTEEVLARIHKQLTIERLQRQLVQKNQELQTLNKELRRSNTELEQFAGVASHDLQSPLQLIMGYADMLRWQYDTLLDEKGEHYLSEISKASQRMNQLIQDLLSYSRVRAGNVELEPIDCEVVLTEALANLQDDINGSGACITHDPLPIVIGDRTQLIQLFQNILSNAIKFRRPQVTPKINISLTFTEQKFAEFRIQDNGIGIAEENYPLVFEIFKRIHPYNQYPGTGIGMSLCKKIIERHGGCIGVDSQLNTGTTFFFTLTLPSQVQP
>NC_019693.1|WP_015149684.1|4357524_4361274_-|PAS-domain-S-box-protein
MKTEGGRSYRGEVLVVDDTVANLKLLVDLLSGHGYKVRAAPNGLLALQAVEVSIPDLILLDIMMPDLNGYDVCKHLKSHEETRPIPIIFISALYETFDKVRGFAVGGSDYITKPFQEAEVLARIEHQIKLQNLERELRERNVQLSWEIQGRNAAEQEKDKLIISLQKSQKSLATAQRVAGVGNWELNWLARHLELSDEMFRVLGMPPQLKPSYAEVLKMIHPQDRSRFSKIIKQAIVSGSSYQIEGRIQRPDGEIRYVEAKGEVILDLHRKPIQIFGTILDITTRKQVKIQLEKQLIRSELLRGITEKIRSELRLEKLLDTAASEIREALGVSGTEIYTYLESRIPSLQIEAFAVAEGYQRSQELELPLDENPYTPKFLEHDRCIPIPNIQTDPLFQPVLSRSPGFQVKSMLLVRTSYKGQPNGALVLHEYDRPREWNLGEIELIETIAAQVGIAIAQANLLKREKQARAKLNQQNQQLQQQINARILTETALKTSESKYRNLVETSQDLIWTIDTKGRITFVNAAVRDIYGYSPSEAMGRAFTELIHPSRWSQDQEFFRKILLEKQEISQYETTHITQAGTPIYMMLNAIPLRDEAGFVIGITGTASNITQLKQTQAKLIETNRLQKAILNSAEHTIIATDPQGTILTFNAAAERLLGYKAHEVTTQANVVIIHTREELQERADTLTAELGYAVAPGFDAIVAKARLGVPDIREWTYLRKDGSRFPVWLSITALQDAIGQITGFLGIGSDITDRKQAEEALKQAAIAAQMANHAKSEFLANMSHELRTPLNAILGFAQVMAGDPSLHPEHQQQIEIINRAGSHLLELINDILEMSKIEAGRTTLKIEPFDLGQMLRDLEDMLQFKAHEKNLLLSTEVTPNVPLYIRADQAKLRQVLINILGNAIKFTQRGAITLRVHRGSGEFEWGNHRDYSTEFLQFEVEDTGPGIAPEEMNLIFESFGQTETGRKSGQGTGLGLPISRQFVRMMGGEIQVNSVVGVGSTFIFVIQVEEVDPSEVPQTQSKGMVIGLAPDQPTKRILVVDDMLESRLLLVKLLGSIGFEVREAENGQEAIATSLQWQPDLILMDIRMPIMDGYEATKQIKAIVGSHKPAILALTASVFEEDRSAVFAAGCDDFLRKPLEKDELLEKIGHHLNTGYIYAPNSSPYQRFKPEAETGEISLEQLQSYLGKMPPQWIAKIYDAAAQCSDDMILELIEEMPPDFEPAGRALTQLAENFQFHQIMHLTYSEDL
>NC_019693.1|WP_015149685.1|4361500_4370281_-|PAS-domain-S-box-protein
MITLSDISLTQKLYESSNSEVYRGYVQASGQPVILKMLKNAYSNPERLGWFWREYEVTRSLNLSGIPRVCGFSNDGNSPFFLLEDVGAESLSRLKIAGNLDLRDFLQLAIDITDILSQIHEQNIIHKDINPSNIVLNPQTRTVKIIDFGISAVLSQENPSFPNANHLEGTLAYMSPEQTGRMNRCIDYRTDFYSLGVTFYHLLSGTLPFQSEDPMEWVHSHIAKPPISLQTIKPQIPATLSNLIAKLMAKNADERYQSGWGLKADLEECLRQLQTENTISRLNLGQQDRSDRFQLPQQLYGREAEIQTLLKAFDRIAEGKRELIFVAGYAGVGKSILVRELYKPVAAKRGNFIAGKFDQYQKNIPYLGLIQALNEFCNFILGETEAVFHEWRSRILAALGNTGQVLIEMIPNLENIIGPQPPVADLGGQEAQNRLHWVVQNFLKALCDRQHPLVIFLDDLQWSDRASLSLLEAILSDRDLQFLLVIGAYRDHEVDDTHPLMMTKAHLQPEFPNLITIALENLTASDVANLMAATLHSPQSLVQPLADLVYEKTLGNAFFTLEFLNTLYQEGLIYFSGDCQNWDWNLAQIQAQEITDNVVDLMARQLVKLSLETQTLLQLAACIGSPFDLETLSRIARSQPEVVFSQLFATLQSGFVIPLTENYKLLRLLPEIDRGKIQFKFLHDRVQQAAYSLIPEAQRPERHLEIGRLLQDSIIPQGCSPHDPSTGLADDLLIMVNHLNQGSELMTEESEKIDLAYLNLWAGKKAKLASAYSLATEYLNCGLRLLPSQSWQTHYDLTLQLHLEAVEAEYLITHYPEVEALAAVVLNQGRTLLERVKVYQILIQLYSAINHLQQAVDTSLRVLEMLGVSLAELAPIQWDIAELSRLPLMEEPDKLAAMQILMSVWGTAIIVTPEWVPRMALTMVKLSLEYGNSPRAAFAYAYYGFNLCRAGEIEQGYQLGQFALELLDQFESAESRCKVYHIFNGFIRHWKEPLPEAIAGLRTTVRLGLETGDIEYTCYATMQYSCYSLLSGEPLEKVIKKHQDSLQIIEKHQQNIQWYYTKIWLQLALNLRINNREVGRLNGEAFDDHQDLQTLTQNKSDTSLFCFHLAQGMLSYYLKEDQKAVESLTIAAQYEAAIASLMPLGQLPFYDSLARLALYPSVEESQQQDFLQRVELNQMRLQDWAKSGPMTYQHKYDLVAAEKARILGQNWQAAELYERAIVGARDHHFLQEAALAYELAGEFYLHREMLQIAELYIQKADALYQQWQGGAKVQQLSAQYPQWLDKPQKQMGSENASETLSETIQSTSSKPEVVLDLVSVLKSSAALTREIEIEKLLGALMKILIENAGAQKGYLIGEENGEWMVQAAIDENLVTTQPGIPLNAVGDGTGEGDLLSGAIVRYVLRTRETVALNNATSEGPFRGDRYIRAQQPKSILCMPILDRTKLSGIIYLENNLISGAFPSDRLEVLKFLSVQAAISLENAKLYTSLRQSESKFNQFLEALPIGISAIDPSGKFHYRNQAGKQLLGEIAPDISLEELSTFYQIYLAGSSRLYPQEQLPGIRALQGEAVMAEDLEILREGERIPLQVYSTPIFDETGQVIYAINAFTDISDRKQAEQLRADYNHTLEVQVAERTEALRESEERFRNAFESAAVGMCLVARNGQLLNVNSAVCQMLGYSKSELLALTIQDITYPEDRESDWSHLEELVQGEISYYHLEKRYQHKNGKIIWGLLSVSLVRDQDNQPLYTIKQIQNITLRKNLELNLQEKTEEIDRFFTMSLDLLCIGDLDGYYRRASLGWERTLGYSIAELEGRLFKIFDLVHPDDVELTLNAMADLNNGREVINVINRYRHKNGSYRWLEWRSMPAGDLIYATARDITESRAAQEKLRHSEANLAKAQEIAHIGSWEFDLVNQSTLWSDELYRIYGLEPSPTSPSLEPIYPRIHPETPGLEQREIQDKLRCAEPWELNQQVQRPSGEIREIEVRGEPVFDREGRLVKWVGTVHDITDRQQIEAKLRQSEAALREAQRIAHIGSWERDLNTDQLTASEEWFQMFGVDPAYPESAYQEHFNAIHPEDRVQLQQNLNRAIVDGRSYQMDLRIMAGDRILRYLEARGEAVRDEKGAVIHLRGTVLDITERKRTVLALSESEERFRTAFDYAGIGMAIVGLDGQWLKVNRAVCEIIGYSESELLTLDFQTITHPEDLDLDLNYAAQLLRGEIGSYQLEKRYIHKQGHSIRVLLTGSLVRTAEGEPLHFIAQIQDVTLQKQAEQILRSQMQREQVLSQFVQSIRNSLELTTISFSAAHESGRLLGADMVKILQYFPEEALWRNVAEYRPFDTLPSTLDLDIPDVKNPVTDGIKRLQPVALAGWEPHPDDPQVELIGSFAGHWLILPLQMGTGVWGALCLARNLSESPWDSTEMELLLAIANQLAIALNQAELYQQVEKAREAADKANQAKSAFLANMSHELRSPLNAILGFAQLLLSNPSLSQEAKENVAIIHRSGEHLLTLINDILDLAKIESGRTTIVETNFNLSHLLDDLQSMFRLKAQSKGLGFVVERSPEVPEYIRTDEIKLRQVLINLLGNAIKFTQRGQIYVAMRGITPEGRSSLSVPDTLEPQTLNLLCEVSDTGPGIAQEELDHLFQAFVQTSTGLEAREGTGLGLSISRKFVELMGGSIEVRSQIGEGSTFSFEIPVKVAGEIESKPIPLQRRAIALEPNQPQYRILIADDRPDNRTFVIKCLQPLGFDLLESSNGQETIALWEEWEPHLIFMDLRMPVMDGYEATQQIKGSIKGQGTAIVALTASYLNQENALSLSSGFDGFIRKPFRDTELFDCLSEQLGVRFVYEDPKADAKPTLTVPPVPLMESDWRDVPLDWLNSFDLATKSCDVELMIALLDEICDRHESFANTLMNWTQNFEFEQISTLIKSVLD
>NC_019693.1|WP_015149686.1|4371400_4371778_-|response-regulator
MNDKLVLVVDDEITVREVVQICLEDLGGWRVLLAPSAQEGLKLAATEQPDAIVLDISMPGMDGFAFLDRLKKNPQSQSIPVVLLTAKALWFTPHQLQQLEVAGAISKPFNSLTLSQMIATMLGWE
>NC_019693.1|WP_015149687.1|4372546_4375315_-|PAS-domain-S-box-protein
MNGSSDWDKSQPQLIAELEELRREVDLLRGETHAPEASPTSIPLSADENRVRNILHLAPLPLMIHAQDGEVIQINKAWTDLTGYHHQDIPTITHWTRQAHPDCSQTVQACIAELYNLQERICTAEYTITTKTGQHRIWEFTCASLGTLADGRRVAISMATDITDRKQTEALLQQTNLELETRVAERTAQLSALTDRLQQQAQLVNLAHDTILTRDLKGQITFWNRGAERMYGISQSEAIGQISHQLLASEFPQPLAEIEAELLRVGYWEGEITHTPPQGTPLVVASRWVLQYDEFQQPLQVLEINNNITRRQQAEADLRETESQFRQVAENIRDVFWSNDINSKQLLYINPAYEKMWGRSSETLYQNPDDWLNAVHPEDRPRVEQGMSETALKGEYDQEYRILLPDGSLRWIHARAFPIRDQGGKLVRVAGLAMDITDRKTAQRALQASQARLAGLVEIARDGIISVDGKQRITLFNQGAERIFGYGAAEVLGQPLDLLMPNRFVRNHRLLVENFGKTSGRTQSMGERTEIIALRADGTEFPAEASISKLEIEGEQIFTAILRDISDRKRTEAALSQLAAIVEDSEDAIFSKTLDGTVVSWNASAERLFGYSPAEVIGQSILNLIIPSDRQSEESTLLEKIIQGESVQQFETVRRRKNETLIHVALTISPVKDGQGHIMGISTIARDISDRHQIERMKNEFISIVSHEIRTPLTSIRGAIGLLASGMYDNKPERVQRMLEIALTDSDRLVRLVNDILDLERLESGRLELVKERCDAAHAIAQAVEGLQAIADKAGVRFSLPPGTATVWASPDALQQVLTNLLSNAIKFSPPQSIITLTVQPQWQGVLFAVRDSGRGIPPDKLEMIFNPFQQIDASDSRQKGGTGLGLTICQRLVHQHGGRIWVESTLGEGSTFYFTLDDPPS
>NC_019693.1|WP_015149688.1|4375311_4377216_-|response-regulator
MKIILVEDDEPASAALSVALRKQNYSVEAASDGETALELATMLECDLILLDLVIPKLDGISLCRKLREQGYQKPILLLTAKDSPQDIVTGLDAGADDYVVKPYNLSELMARIRALLRRGTTPVTETLTWLELCLNPVSGEVTWNGQSLGVTATEYKLLELFLRNPQRVFSRSAIIDRLWSFDDSPTENAVTVHIKDLRQKFKAIGIDNDPIETVYGLGYRLKPATEPNPETPETEPAPGSKTPTPGKKLQAIASIAQILEKYRPRLNEQIALLRQAYNALAAGELTNELQERAIQEAHKLAGSLGPFGYLEGSNLARKIEYLLMSPTPLKTAETHQLEQLTRALAAELTKPPTEISLEVPSSPQAPTLLVVDSDRAIATALNTQAANLGMGVESALTLTAARQAIAQTTPDLILLDIACPETSTSPGEKAGLRWLQEVAHQFPTLPILVFTALDNLADRVAVSRCGGRGFLLKPASSDQILKAIAQVLPPKATPEAKVLIVDDDPTALAVMKELLQPWGLEVTTLDNPEKFWEILTAVAPDLLILDLEMPKFNGIDLCQVVRQDPDWGDLPILVVTAHTDAQSLRQVFAVGADDFIGKPIVGPELVTRITSRIERDRFRQQLEALKHQTKEKQP
>NC_019693.1|WP_015149689.1|4377472_4378093_+|hypothetical-protein
MGIQIKQLYRAFQLYQKSGKLGDFALLKADALGAKANPNLAPKLAAVTGYYPDIHVEHLLQHPPGTFGREYAEHLTTNRLKPFNVSPEFDAIAQRNVFALRYAVTHDIFHCLLGFDTSYAGEIGVLAFAAAQNYSPSLQVGLTFAKLLYPLLAPRQRGAIRANLAKGEELGKQADFLLGYRFEDHWHEPVAEVRQRLGLPATVEES
>NC_019693.1|WP_156823874.1|4378653_4378854_+|hypothetical-protein
MSSDNQTAPHLHTQKEVEEAVKEYKNSDLSGTELMPLWQAIHDASLDLAGTKAVETEDEVPGDDSY
>NC_019693.1|WP_156823875.1|4378869_4379013_-|hypothetical-protein
MRSLPDGKYGFTVSPEKPCAAEPNCDRKFSIGGIPTGMLGGIECSCL
>NC_019693.1|WP_015149691.1|4378973_4380458_-|glutamate-synthase-subunit-beta
MGKPTGFIEFLRELPSELNPLDRIANWDEFHLHMEEEKLQTQASRCMDCGTPFCHTGTLISGMASGCPVNNLIPEWNDLVYRGLWHEALDRLHKTNNFPEFTGRVCPAPCEGSCVLGITNPAVTIKNIENTIADKGWDEGWITPEPPEKRTGKKVAVIGSGPAGLAAAAQLNRVGHGVTVYERADRPGGLLMYGIPNMKLDKEQVVLRRIKLLEDEGVKFVCNTEVGKDITAQQLMEEYDAVILCTGATKPRDLPIEGRDLQGIYFAMDFLTGNTKAVLDRHKNGSFISAEGKDVVIIGGGDTGTDCVGTSVRHGCNSVVQLEILPKPPETRASNNPWPEWPKVYKLDYGQEEAAAKFGADPRVYTTTATKFEGDDKGRVKAVHTVVVEWLKDEQGRFTPKPVPGTEKVVPTQLVLLAMGFLGPEQPLLDSLGLERDGRSNVKAEHENYTTSLPGVFAAGDCRRGQSLVVWAINEGRGVARECDRYLMGNTDLP

Crispr_ID: NC_019693_40

• CRISPR_ID: NC_019693_40
• CRISPR_location: 4399528-4399638
• CRISPR_type: Orphan
• Repeat_type: I-D,II-B
• Spacer_info: 1 spacers
• Cas_protein_info: DinG,RT

Consensus repeat of NC_019693_40

Consensus_repeat	Method
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CRISPRCasFinder

spacers of NC_019693_40

>40.1|4399565|37|NC_019693|CRISPRCasFinder
CCTTTAATTTGTCCGAGTTGTTTGAGCGTTATGAACA

CRISPR arrays and Neighbor proteins around NC_019693_40

CRISPR arrays

The CRISPR arrays of NC_019693_40

>merge|NC_019693|40|4399528-4399638|CRISPRCasFinder
GTCTTAATGACCCATAATCCCTTTCAGGGATTGAAACCCTTTAATTTGTCCGAGTTGTTTGAGCGTTATGAACAGTCTCAATGACCCCTAATCCCTTTCAGGGATTGAAAC

>NC_019693|40|40|4399528-4399638|CRISPRCasFinder
GTCTTAATGACCCATAATCCCTTTCAGGGATTGAAAC	CCTTTAATTTGTCCGAGTTGTTTGAGCGTTATGAACA
GTCTCAATGACCCCTAATCCCTTTCAGGGATTGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015149696.1|4384016_4384244_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044197345.1|4399680_4400196_-|damage-inducible-protein-DinB	unknown	unknown	gnl|CDD|225200
NC_019693.1|WP_015149704.1|4399001_4399376_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149697.1|4384233_4384476_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149701.1|4388294_4392884_-|glutamate-synthase-large-subunit	unknown	unknown	gnl|CDD|236968
NC_019693.1|WP_015149706.1|4401019_4406506_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|274362
NC_019693.1|WP_015149698.1|4384563_4385073_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149703.1|4394084_4394426_+|hypothetical-protein	unknown	unknown	gnl|CDD|375906
NC_019693.1|WP_015149709.1|4411968_4412565_-|peroxiredoxin	unknown	unknown	gnl|CDD|239313
NC_019693.1|WP_156823876.1|4400232_4400424_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149695.1|4382577_4383573_-|hypothetical-protein	unknown	unknown	gnl|CDD|366612
NC_019693.1|WP_015149711.1|4413686_4418000_-|response-regulator	unknown	unknown	gnl|CDD|236848
NC_019693.1|WP_044194328.1|4408777_4410535_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209
NC_019693.1|WP_015149710.1|4413261_4413690_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149700.1|4385623_4388194_-|DEAD/DEAH-box-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl|CDD|224125
NC_019693.1|WP_015149702.1|4393733_4394081_+|DUF433-domain-containing-protein	unknown	unknown	gnl|CDD|225291
NC_019693.1|WP_015149707.1|4406502_4408338_+|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|236645
NC_019693.1|WP_015149708.1|4411242_4411803_-|redoxin-domain-containing-protein	unknown	unknown	gnl|CDD|224146
NC_019693.1|WP_015149712.1|4418595_4420107_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|131777
NC_019693.1|WP_015149699.1|4385207_4385399_-|YgiT-type-zinc-finger-protein	unknown	unknown	gnl|CDD|240606

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_015149700.1|4385623_4388194_-|DEAD/DEAH-box-helicase	DinG	COG1199_DinG_CAS-IV-A	1.2e-12	41.6	0.7
NC_019693.1|WP_044194328.1|4408777_4410535_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	7.5e-46	151.1	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_044197345.1|4399680_4400196_-|damage-inducible-protein-DinB	gnl|CDD|225200	COG2318, DinB, Uncharacterized protein conserved in bacteria [Function unknown].	4.3785e-43
NC_019693.1|WP_015149699.1|4385207_4385399_-|YgiT-type-zinc-finger-protein	gnl|CDD|240606	cd12870, MqsA, antitoxin MqsA for MqsR toxin. This family includes domains similar to the antitoxin MqsA that binds motility quorum-sensing regulator MqsR, a toxin that is highly upregulated in persisters (dormant cells found in biofilms that are a source of antibiotic resistance), thus forming a unique toxin:antitoxin (TA) pair. MqsA neutralizes MsqR toxicity. It binds its own promoter as well as those of genes important for E. coli physiology, such as mcbR and spy. It also binds zinc and has been shown to coordinate DNA via its C-terminal domain. This family also includes the B. subtilis YokU protein, which is functionally uncharacterized.	4.37541e-08
NC_019693.1|WP_015149702.1|4393733_4394081_+|DUF433-domain-containing-protein	gnl|CDD|225291	COG2442, COG2442, Uncharacterized conserved protein [Function unknown].	1.39407e-16
NC_019693.1|WP_015149701.1|4388294_4392884_-|glutamate-synthase-large-subunit	gnl|CDD|236968	PRK11750, gltB, glutamate synthase subunit alpha; Provisional.	0
NC_019693.1|WP_015149706.1|4401019_4406506_+|PAS-domain-S-box-protein	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	9.04401e-79
NC_019693.1|WP_015149703.1|4394084_4394426_+|hypothetical-protein	gnl|CDD|375906	pfam18480, DUF5615, Domain of unknown function (DUF5615). This is a domain of unknown function found in potential toxin-antitoxin system component.	1.00021e-24
NC_019693.1|WP_015149709.1|4411968_4412565_-|peroxiredoxin	gnl|CDD|239313	cd03015, PRX_Typ2cys, Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. The functional unit of typical 2-cys PRX is a homodimer. A unique intermolecular redox-active disulfide center is utilized for its activity. Upon reaction with peroxides, its peroxidatic cysteine is oxidized into a sulfenic acid intermediate which is resolved by bonding with the resolving cysteine from the other subunit of the homodimer. This intermolecular disulfide bond is then reduced by thioredoxin, tryparedoxin or AhpF. Typical 2-cys PRXs, like 1-cys PRXs, form decamers which are stabilized by reduction of the active site cysteine. Typical 2-cys PRX interacts through beta strands at one edge of the monomer (B-type interface) to form the functional homodimer, and uses an A-type interface (similar to the dimeric interface in atypical 2-cys PRX and PRX5) at the opposite end of the monomer to form the stable decameric (pentamer of dimers) structure.	9.80971e-115
NC_019693.1|WP_015149695.1|4382577_4383573_-|hypothetical-protein	gnl|CDD|366612	pfam01393, Chromo_shadow, Chromo shadow domain. This domain is distantly related to pfam00385. This domain is always found in association with a chromo domain.	0.00850528
NC_019693.1|WP_015149711.1|4413686_4418000_-|response-regulator	gnl|CDD|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	4.82802e-109
NC_019693.1|WP_044194328.1|4408777_4410535_-|group-II-intron-reverse-transcriptase/maturase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	6.87539e-123
NC_019693.1|WP_015149700.1|4385623_4388194_-|DEAD/DEAH-box-helicase	gnl|CDD|224125	COG1204, COG1204, Superfamily II helicase [General function prediction only].	1.08474e-44
NC_019693.1|WP_015149707.1|4406502_4408338_+|EAL-domain-containing-protein	gnl|CDD|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	1.90464e-120
NC_019693.1|WP_015149708.1|4411242_4411803_-|redoxin-domain-containing-protein	gnl|CDD|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	7.05157e-25
NC_019693.1|WP_015149712.1|4418595_4420107_-|FAD-dependent-oxidoreductase	gnl|CDD|131777	TIGR02730, Carotenoid_isomerase, carotene isomerase. Members of this family, including sll0033 (crtH) of Synechocystis sp. PCC 6803, catalyze a cis-trans isomerization of carotenes to the all-trans lycopene, a reaction that can also occur non-enzymatically in light through photoisomerization. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	7.39986e-111

Protein sequences

>NC_019693.1|WP_015149704.1|4399001_4399376_+|hypothetical-protein
MNSSFTRSELRKVAKYYRLVSWAILASLGVNLLLLLSASSPSTQLIVLILLIVVGIFQFYVLYNLGKSLNLPGALIILIVLSAFVPLLALALLAYMHDRAMKLFKSAGVKVGFMGANPASIKDE
>NC_019693.1|WP_015149703.1|4394084_4394426_+|hypothetical-protein
MARFYVDENFPLPVVELLRNLGHDLLTVREAGKANLGIPDAEVLAFSIECDRAVLTGNRRDYIKLHRLQPNHAGIVVCTEDPNFERLAQRIDQAISDEETLQGKLIRVHRPLE
>NC_019693.1|WP_015149702.1|4393733_4394081_+|DUF433-domain-containing-protein
MTIAELRTQLLALTPAEKAEAIQTLIQTLDNGSLGITKTPGVCGGDACIANTRIPLWSVINYRRLGAGDRMILEAFPYLTAADLVNVWAYAEAHPEEIERAIQENEEIMQGDEED
>NC_019693.1|WP_015149701.1|4388294_4392884_-|glutamate-synthase-large-subunit
MNHQKLPQKQGLYDPQFEHDACGVGFIVHQKGQKSHSIVEQALTILLNLDHRGACGCENNTGDGAGILIQVPDAFLKKVAAAENISLPNAGEYGVGNIYCSQDPAIRQQSRQQFEKIVAEEGQKVLGWRDVPTDHSSLGNTAKSSEPFISQVFIQRSANITDDLAFDRKLYVIRKRAEREIHISQLDSFWYVCSLSCRTLVYKGMLMPVQVGDYFPELHDETMESALALVHSRFSTNTFPSWERSHPYRYIAHNGEINTLRGNINWMHARESLFESELFGEDLKKLHPVIDLEGSDSAIFDNALEMLFLSGRSLPHAVMMMIPEPWTAHESMSPEKKAFYKYHSCLMEPWDGPASIAFTDGTMMGAVLDRNGLRPSRYYVTKDDLVIMASEAGVLPIEPERVAYKGRLQPGRMFLVDMKQGRIISDEEIKTQIVSEHPYQQWIDENLVALSQLKDAPQLREMDPVPLIQRQMAFGYTFEELRLLMTPMATNGVEAIGSMGTDTPLAVLSDRPKLLYDYFQQLFAQVTNPPIDSIREEIVTSAETTIGAERNLLKPTAKSCNLIELKTPVLTDEELAKLKAVNEGAFKSTTIPMLFDPTTGVKGLEAALEAIFAQATQAIATGTNILILSDRGMNREKVAIPALLAVAGLHHHLIRQGTRTQVGLVLESGEPREVHHFAALIGYGCGAINPYLAFETIDDMIREKLLVNVEYKTAVKNYIKAVTKGVVKIASKIGISTIQSYRGAQIFEAIGLNQSVISRYFTWTASRIEGVDLEAIANETIMRHSHAFPDRDANGHTLDVGGEYQWRKDGEAHLLSPEIIHALQQATREGNYELYKKYAAKVNEQNQKFFTLRGLLEFKAQQPIPLEEVEPIESIMKRFKTGAMSYGSISKEAHESLAIAMNRVGGKSNTGEGGEDPDRYTWTNERGDSKNSAIKQVASGRFGVTSLYLSQAKEIQIKMAQGAKPGEGGQLPGLKVYPWIAKVRHSTPGVGLISPPPHHDIYSIEDLAELIHDLKNANRNARVNVKLVSEVGVGTIAAGVAKAHADVVLVSGFDGGTGASPQTSIKHAGLPWELGLAETHQTLVLNNLRSRIVVETDGQMKTGRDVAIAALLGAEEYGFSTAPLVTLGCIMMRVCHKNTCPVGIATQNPELRAKFMGDPEYAANFMRFIAQELREIMAQLGFRTLTEMVGRTDLLEPKKAVDHWKAKGIDLSNILYQPQVGPEVGRYCQIPQDHGLEKSLDMTVLLDLCKGAIDNGEKVKATLPITNINRVVGTILGNEITKKHWDGLPDGTIHLHFQGSAGQSFGAFVPKGVTLELEGDGNDYIGKGLSGGKIIVYPSKKSTLVPHENIIAGNVALYGATSGELYLSGIAGERFAVRNSGVHAVVEGVGDHGCEYMTGGKVVVIGPAGRNFAAGMSGGVAYILDEAGDFATRCNTQMADMEKLEEPSEIAIVREMIQKHADYTNSPKAAAVLANWEEMVPKFVKVMPRDYKRVLQALESALASGLSGDDALDAAFEQNARDVARIGGS
>NC_019693.1|WP_015149700.1|4385623_4388194_-|DEAD/DEAH-box-helicase
MVDFKKRLGFRAIEKKINPVEIYDELDRRSETGPLRPVQQQVLAEWWSNRKEDKDLILKLHTGQGKTLIGLLMLQSQLNQKKGPCLYVCPNKYLVEQTCQEAEKFGIGYVKIGPDNSLPEEFLSSEKILITHIQKFFNGKSIFGIGGKFVTVNTIILDDSHACIDFIKKSFKIVLKKEHELYLKILNLFKQDLNKQGEGRLFEIQNGSGENTSIPVPYWSWEDKKQEIIAFLGEYNEDKDITFTWPLIKDRIGNCQCIISGREIEISPFVSLIHEFRSFGQARHRILMSATTQNDSFFIKGFGLSVESVKNPLTHKYEKWWGEKMILIPSLIRDDLDKNKIIPRFAQSKETREVGIVVITSSFKKAKLYENNGAVICKTEDIFERVNQLKNGHDYSKTIVFVNRYDGIDLPDDSCRLLIMDSLPYANSLSDKYEEECRSNSDFINIQIAQRIEQGMGRSVRGEKDYSVIILLGKDLIKFVKSSLTNKFFSSQTRKQIEIGLEIANIVNEDNSEQPQSPKNQSLHILQELMKQCVARDEGWKEFYREKMNDVNQDENFYQSQEIDILSLEKKAADSFYKNDAESAVKYIQQLIDSYCQDRTDDDDDDEKAWYLQILARYKYTLSKVDANKIQKSAYQKNQRLLKPQDGITYEKTNYINDGRIKKIKTWIMSDPSYEQLMLKVEAMLDDLSFGQPSEKFERALQDLGKAIGFQSKRPDREFKTGPDNLWCVENNDYFIFECKSEVDDNRREIIKTETGQMNNHCAWFEQEYKTARVKTILIIPTNKVASNANFTHEVTIMKRNKLESLKNSVKGFFKEIKDYKIPELSDAKIQEWLLVHKLDLKSLKTHYTESYYPKK
>NC_019693.1|WP_015149699.1|4385207_4385399_-|YgiT-type-zinc-finger-protein
MTNNFPQETLIEKRVTYTLEMNGKFFMIENVPARVCEKTGESFFSPETVVRIQQMIWGQEKPK
>NC_019693.1|WP_015149698.1|4384563_4385073_-|hypothetical-protein
MQILAITEVDFYKIDRCRRVISHDCAQKFAAIDLGVPLGCYGLSWRSDILEPIIVRSPDRLTVWIGVDQQLAAISLDEGRIIVALPLTDYLVQIVAIADVIAVLTQEKVLLFNPGGSIRFSDDLPDQGIGMTVEGENLVIQMLEGESLTLNPMRGYFQSMAASMTRRSP
>NC_019693.1|WP_015149697.1|4384233_4384476_-|hypothetical-protein
MSITELFPIVQNLSPAEKIRLLEFLQAEIEQSQSASESSESMHPRLHRKNDILVIETVPLNHIDFNRLIRENQINTCNGN
>NC_019693.1|WP_015149696.1|4384016_4384244_-|hypothetical-protein
METKTITIRVNAEAARIFENASEEQQRKLEVLLSLKLTEATRSTQSLEELMSDISSKAQKRGLTPEILGAILNDE
>NC_019693.1|WP_015149695.1|4382577_4383573_-|hypothetical-protein
MSKNIRLFSNYVQRENQTTNYCLLILKLLYEENPKFLSEVLSTLLGERLSGAVGVKFSQQNRGKKSVPDGKISQEAFSIVIETKRDNRFNLEQLSRHLEPMKEEAGIQVLMALGNFEWEEPNPEAFQDIDRLAEEMGVAFAAVSFEQFLQALKLSYLPKNLVDAIADLEEYMNEENLLPSWKYHLDVVNCRVSFDDVLQHQIYVCPATDGSYNHRRSLYFGMYRNKRVEQVGKIEAVVDLESEETFSIKWKNIEKSDLELVEMARSRRSQIDDSWYPARVFILADLHSTDFVKASPGGMQSSKQYFDISQLNIMNAEDLARKLTGKSWENY
>NC_019693.1|WP_044197345.1|4399680_4400196_-|damage-inducible-protein-DinB
MHNRNTYQLMAEYNCWMNQNIYQVCESIPDEQRKQDRGAFFKSIHGTLNHLLYGDKVWMGRFTNQPFSGTSLSQELYADFAELRAEREQTDEQILDWSKTLDPDWLNQPFEYVSQSGQKRPVMPAWILVTHLFNHQTHHRGQVTTLIKQLGYEPGVTDIPWMPGVSGLGSE
>NC_019693.1|WP_156823876.1|4400232_4400424_+|hypothetical-protein
MKLDKTAARRRRSHLNPDPAIAILNEFDLKKTSKMLVLTHWLRQRTPKMYDNNCGKRYILNQL
>NC_019693.1|WP_015149706.1|4401019_4406506_+|PAS-domain-S-box-protein
MDIIRGQYEPVLVTLSLIIGAIAAYTALDLAGRVNPNSSMRSRLIWSVGGAVAMGTGIWSMHFIAMLALRLPVPTAYNMPLTLLSWVDAIVASALAMLLYNRQQLRVGLLVGGGVVMGLAIASMHYLGMAAVQVPARVEYNPWGVTLSVAVAIFASTAALGLAFQVRNSLSPHREWVKLGSAGIMGVAIAGMHYTGMWATCFAAISHPEAILIEGADQSWLAMQIGLGTLILLIGTLITSLVDRRYQSHLLREQALQESETRFRTLVENMSVGVLLLDKNGTIVLSNPLASELLDVPESELQGKNAFEFNWQILSLDGTILIQEQHPLQMAVAQGQPVQNQVTGICRWGKKDTVWLLLNMDPQLDASGQVERVVCTFSNISDRKQSEDEIRLLLDTNQAIRHAPDLESALASVLRCICMTINWDVAEAWLPDENQQFLTYRPGWYYPEPDVEAFRLQREPVIYRVGEGLPGRVWESRQPEWIENLTEETDFLADAVMAVKQGLKASFAVPIIRGNGILAVLTFFKRTESPRDDRAIALVGAVATQLGSSIGQKVAEAALSESERRLQLALEGSDLGIWDWQIPTGKTYFDPQWKGMLGYEVEEIGNQYQIWEDLLHREDRKPTLRALQDHLAGILPVYERELRMKSKSGEWKWILSRGKVVERDPSGIPLRMSGTHKDITPRKAAEAALEESQRRYQTLAEASPVCIFHTDAQGNCLYVNQRWTELTGLSLERAIGKSWIANLHPDDFKRVQSEWFLAAETRMPFKSEYRFVRPDGIVVWAIGQAIAEIGEDGLVKGYLGTITDISERKRAEIALQQQLKRERLVSSIQERIRSSLDLEEVLETAVKEVRGFLATDRILIYRFSPDWSGVIAVESVGSDWMSVKGIEIEDRCFIETHIPLYAQGRIRAIDNIHTTGLSECHVELLSQFAVQANLVVPLRQGEQLWGLLIAHHCSGERQWHESEIESLRQLSVQLSIAIQQCTLFEQAKTELLERKRAEDALRESEERFKLAVSGTNDGIWDWDLKNDQIYYSPVWMQILGYEEGELPYRVSTWFNKVHPDDLSVAMQTLQDHVQGQNPLYYYHTHRMERKDKSWIWVEVKGKCIRNEAGEAYRLTGTLTDITERKQAEEALQESVQRERALSQVIQRMRETLDLETIFSATTRELRQVLKCDRVLVHHFHDDWRGEVVAESTGPEWISLMDNIQDLPETAVNLNGGDADSLEDPEVALEDWYMQSARTEHWNSGLTYLAVEDVYSAGFDEAYLNILEQFQAKAYIIVPIFSGNKLWGLLASYQNSGSRHWKEAEIKVVVQIGNQLGVALQQAELLEKTQRQSHALQKAALAADAANRAKSEFLANMSHELRTPLNAILGFTQVMARDASLKPENHEHLKIINRAGGHLLALINDVLEMSKIEAGRMSFNSVNFDLLNLLKSLNEMFQIKAESKQLQIIFEGWDELPQFVKTDESKLRQVLINIVGNAIKFTETGHVILRIEVTDAPTGVNPDPGDFSDSGNPGKFLYFEIEDTGPGIAPEEMGKLFEPFGQTETGRKSQQGTGLGLPISRKFVQLMGGDIQVTSIVGQGTVFAFAVAIAPSSEGEVQTRQTKRRAVAIAPQAQANESRILVVDDAFESRLLLKTILKSLGFQVQEAENGQGAIAVYQSWKPHLILMDMQMPVMDGYEATRHIKSTAQGQKTTIVALTASAFEEERKMILDAGCDDFIRKPFLEELLLETIGRYLNIDYIFEDLSPDQNRPQPDSPTSQYSLSPEALKVMPESWINQLSDAATQCSDDLILRLLEEIPPDLAPLSQALAELAHNYQFDLIEELTQQEGQ
>NC_019693.1|WP_015149707.1|4406502_4408338_+|EAL-domain-containing-protein
MNTEPLQTLQKDILIVDDTQDNLRYLATILTEEGYKVRKALNGQMALKACRVVVPDLILLDIMMPDMSGYQVCEILKENEATREIPVIFLSALDDAFDKVKAFNVGGIDYISKPFQLEEVLARIQTQLLRRDAELKIQQLNAELETRVQERTLQLEESNQELVQEIKERKQLQERLLHLALHDPLTNLPNRALFMERLAQAIAFRKANPDYQFAVLFLDCDRFKVVNDSLGHLVGDELLIAIAKRLQSALRQEDTLARLGGDEFAVLVEELPTLDRAQTIADRILHSLTEPFQLSRYEVFINASIGITLSSFYHEKPEYLLRDADTAMYRAKALGKGQYYLFDPGMHDEALNRLQLENDLRRAVERLEFKVYYQPIISLTTGRIYGFEALVRWQHPTRGFISPLDFIPIAEETGLIANIDLWVLGETVRQLQAWQHQNLINDTVTCSVNLSARHFLQFSFIQHLRELLESTQINPQMIKLEITESAIANKNQATLDILHQIRDCQIELSIDDFGTGYSSLSYLEEFPVNVLKIDRSFIKRIDGQEHQCGLVPGIIGIAHTMGMIAIAEGVETPIQLEKLRGLGCDFAQGYLFSKPLDPEAIGELLARSPQW
>NC_019693.1|WP_044194328.1|4408777_4410535_-|group-II-intron-reverse-transcriptase/maturase
MTVAMNTVKTSLKTTETWNAIPWTKVQRKVFKLQKRIFQAAKSGQDAKARRLQKLLTSSYYARLLAVRKVTQDNQGKKTAGIDGVKSLKPKQRLELAKDLGKHSKAKALRRVWIPKPGRDEKRPLGIPIIRDRAEQALVKQALEPEWEARFEGTSYGFRPGRSAHDAIGRIYASINQGSYYVLDADITKCFDKINHEYLLSKLDCCLQHRRQIKQWLKAGVVDNGIFEDTESGTPQGGVISPLLANIALDGMARLIEELYPKRKGQKVKATLIRYADDFVVISPEIEIINQCKIALENWLKFVGLELKPEKTKICHTLREIEVNGEKVTPGFDFLGFTIRQYPVGKYKSGKTGGANSRLIGHKTHIKPSAKAIKAHSEALKGVIKNHKTAPQAALISRLNPIIRGWSNYYSGVVSMETFNQMDHNIWQQLRAWTVSRCGQANLEKLRKYFHKVTVKIGNGKERNEKWLFQAKDGLSLWKHSYTQITRHTLVKPEASPYDGNWSYWATRRGTSLEVPMRVAKLLKKHSGRCSRCGQYFAMEDLMEVDHIQPLSMGGKDEYRNLQLLHRHCHDKKTAEDMQNVKSYQ
>NC_019693.1|WP_015149708.1|4411242_4411803_-|redoxin-domain-containing-protein
MLTSTDFRGLLNQRFFNNFLPVPALNKLYPEVCPPDFQLPHVNGEGSIRISEYREKQPVILYFTRIFTEKQYCPLCFPHIKAMNTAYEQFVEAGAEVLLITSTDERQSQIVIRDLGLKMPVMCDPSCLVFRAYGTGQALGAPLPAQYLLDIEGKLRFKHLFSFLEPNAQVSRLLEQLQQLPQPAGV
>NC_019693.1|WP_015149709.1|4411968_4412565_-|peroxiredoxin
MTEGCIRVGQQAPDFTATAVVDQEFKTIKLSDYRGKYVVLFFYPLDFTFVCPTEITAFSDSHGKFSQLNTEVLGVSVDSEFSHLAWIQTDRKSGGLGDLNYPLVSDIKKEISSAYNVLDPEAGIALRGLFIIDKDGVIQHATINNLAFGRNVEETLRILQAIQHVQTHPDEVCPAGWQPGAKTMNPDPKKSKEFFAAI
>NC_019693.1|WP_015149710.1|4413261_4413690_+|hypothetical-protein
MQLPTRPLIAPLFAVLLAAVAPHRLHAEVVQLQPQFNSDPIQLQGTSGGVQKSDCGSISEQPSQTLEVGQQFPYLRLRVESAGEPTLLIEGPTGRFCVLADSTVGEQPEMSGLWTVGTYQIYIGDLAGEQHNYTLSISENPN
>NC_019693.1|WP_015149711.1|4413686_4418000_-|response-regulator
MKLRKKILIIVGTTLLGLNVVLYATASSILLGDFKDLEQKVVHQDAIRGLQSLQQTLNELKSIARYHAEWDDTYSFITPGDPNYVNSNFGNETFVQLKLNLLLILDEQRRPVFSKAFDFQEKVEIPMPEVIQDLASAYQQQVEKKFTETGHHNHPLSGIVLLPQGPALIAAQSILTSQGEGPYRGTLWVGRFLNEAEIDRLAELTQLSLNVYPISALPPELDGVRTELEGASPSPTDSEPFQGMDLGGPGRSPIVVKALSEREMAAYTPIPAISSNTPLLLQINHNREIYAKGKISVRYFIGSLLGVSLGFSGLTLLLFEKLVLSRLTVLSRKVERIGDKGDLSMRVKIAGHDELSSLGVTINGMLKALQESQYKLQESEERYRLMAENSTDMISRHTPKGKFIYVSPACHSLLGYEPDELIGCNLYDFFHPEDAKTLAKSYLAMVKGQVSYTVSYRIRHKYGHYLWFESTSRTVRNPQTDDIEELVAISRDITERHQTDEELRESEASIRALYKITSSRKLSFEQRLQRLLIMGKRRFGLSVAILSRIKRDRYEIIAVQSPDDTLQPGDRFPLSQTYCRETLRLKEPLYFESVSVTRWHSKPTQTAFPQEAYIGTRVIVGGKIYGTLSFSSSTPLGRPFKAVDKELLKLMAQWIGSEIERRAAAADLARARDEALAATRAKSEFLATMSHEIRTPMNAVIGMTGLLLDTDLNPEQRDFVETVRASGDALLTIINDILDFSKIESGKLDLEQQPFNLRSCIEDSLDLLASRAAEKGVELAYLIEPSTPEMIIGDVTRVRQILVNLLSNAVKFTEKGEVVVSVSASAIPPQQAGGIGTDSLILKDQETTNGHLHKDLNPDSSAGNPLCQIQFTVSDTGIGIPPERMNRLFKSFSQVDSSTTREYGGTGLGLAISKRLSELMGGRMWVVSGEGVGGDPDPAFQWPIASSVQEQSSPMPDPEQSIFTLTDAKSDQADTPPTGSTFYFTVMATPAVNPLPVDLNGTQPSLAGKRVLIVDDNATNRQILTRQALFWGMKPKAASSAREALDWLQNSEMFDIAILDMQMPQMDGITLASYIRGIVKNREFPLVMLTSIGRQEVDLPDKVPFAAFLNKPIKQSYLYNVLAGIFGGVPILSRPVHLNAVAIDPQMAQQKPLRILLAEDHLVNQKVALQILHRLGYRADVAGNGIEVLQALDRQHYDVVLMDVHMPEMDGLAATRQICQDALDGRLSHRPRIIAMTANAMQGDRELCLDAGMDDYISKPIRMPELVEALALTPVDSDHSPHHLTPTLSRADSEGPGSKLFGSDSEHPPGSPSMAIADPVLNPAMLESLREIEALEEVIEIYLEESPKLIDLLTVAIAQDDSFELQEAAHSLKSTSAAVGAMSLADLSQQLESIGRSHHNTNTPPPPEVTEIFSDLILEYQRVKTALNWELEQGESS
>NC_019693.1|WP_015149712.1|4418595_4420107_-|FAD-dependent-oxidoreductase
MTEYDAIAIGSGIGGLVTAALLARYGKRVLVCESHGIPGGAAHGFDRQGFHFDSGPSFYCGLGDSQSLNPLRQVLELLGESVPTIPYDPLGHYHLGDITLPIYGSCDRYRAEIATITPTGAQELQRFERRMLSLYDALKGIPTLILRSDRKLLPVLLSYWPALLKLLPHLGEIQGSVGQLLDRDVKDPFVRRLIDLECFLLSGFKAHGTIAPEVAFMFGERSRSAIDYPIGGSTALIEALVRGLTRWGGELRLNAHVERILVEAGRVTGVRLRNGTLLKAPIVISNATIWDTYTHLLAPEDLPESYRRQALETPVLDSFMHLHLGIKAEGLTGLTGHHVVVHDSDRDLTEPGNTCMISIPSVWDPKLAPPGHHGIHAYTMEPYHSWQSDVAYKARKRQRAQSLFRALERVIPDLRDRIVLELIGTPLTHAKFLRRDRGTYGPAIAAGKGTFPSIHTPIAGLYRVGDSTLPGIGVPAVAASGILCANTLVEPEQTAQLLKTHRT

Crispr_ID: NC_019693_39

• CRISPR_ID: NC_019693_39
• CRISPR_location: 4394995-4398974
• CRISPR_type: Orphan
• Repeat_type: NA:I-D,II-B
• Spacer_info: 54 spacers
• Cas_protein_info: DinG,RT

Consensus repeat of NC_019693_39

Consensus_repeat	Method
GTTTCAATCC--------------------CTGAAAGGGATTAGGGGTTATTGAGAC	PILER-CR
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CRISPRCasFinder
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CRT
GTTTCAATCC--------------------CTGAAAGGGATTAGGGGTTATTGAGAC	PILER-CR

spacers of NC_019693_39

>39.1|4395032|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ATGTCGCAAACGGAGCAGATGGCGCAGGACCTCTTC
>39.2|4395105|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CGCCTGGGGGTTTAATCATTGGTGCACAGATTAGG
>39.3|4395177|33|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GGTTGCCGGGTTAATCACTAAAATCGAGGTTGA
>39.4|4395247|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CAGCGTGATCTTGATTTAGTGATGCAGCAACTCA
>39.5|4395318|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CAGCGTGATCTTGATTTAGTGATGCAGCAACTCAA
>39.6|4395390|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TCAGCCATTTCTATCCTCGGGGTGTGTCATTTGA
>39.7|4395461|44|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AAGTAGAGTATCCCTTTATCCCGGCTGCTTTACAGGCAGCCCTA
>39.8|4395542|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GTAGTAAACGGGGATAACTCGGAAGGTTTTCATG
>39.9|4395613|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GACACCCTGATTAAACCGACCGGACTGATTTCCT
>39.10|4395684|31|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GAATAAGATCGGCAATCTCGTTTGTACCCAT
>39.11|4395752|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TCTAACCATCGATCATGCCACTGAGCGCCAAAGCG
>39.12|4395824|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TGGGTTTGTCGTACCGGAACACCTGCGAGAACAA
>39.13|4395895|41|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CTCATCCTTTTTGGCTTGGATCGCCATTAGGACAACACTAA
>39.14|4395973|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TGGTTACTCACTTGAACTCCTTAACAAACTTGGTT
>39.15|4396045|33|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AGAAGCCATCTCCCATGCGCCATTTCCGAGAAT
>39.16|4396115|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ATAATCTTAAAAAGAATATATATAGACAAAAAAATG
>39.17|4396188|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTTCTCTTTAACAAAATGAACCCAGAAGTTTCCAT
>39.18|4396260|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AGTGAACAGCCTGTGGTCGTTGAGCGTAACGTTC
>39.19|4396331|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CTATATTAAAGGATTTAGTGTTATTGGCTTATGTA
>39.20|4396403|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTAAGCTGTGCGGTCCAGAGCTCCGGATAGCTCTT
>39.21|4396475|41|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AATAGTTGGGGTGGTGAAGCTAATTTTGGCAAAGCCTTGTG
>39.22|4396553|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CTCGTTCGGCATCTGTAGGAGTTGCGGGTGCTGC
>39.23|4396624|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CTCTCTTTCTAATTCTCCAATGTAATTCAAAGCAGT
>39.24|4396697|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTTGCCCTGGTGATTGCCTTGGCTAAATCAAACGAC
>39.25|4396770|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GGAAATCTTTGCTGAAAGCCGTGAGGTAAGACCG
>39.26|4396841|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AAGTCAATCATCATCGTCCCCATTTAGTCTCTTC
>39.27|4396912|39|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GATTAGCTTATTTGCGGAAGGCTAGAATAGTCCGTGCTT
>39.28|4396988|35|NC_019693|CRISPRCasFinder,CRT
TGTAGCCATCAGGCAAAATGCCGATGGTGGCGCTA
>39.29|4397060|64|NC_019693|CRISPRCasFinder,CRT
ATAGGGCTTTCGATCGGTGGCGCGACCCCAGCTTGTTGCCGGGGGCTCATCGGAAAGAGGGGCT
>39.30|4397161|34|NC_019693|CRISPRCasFinder,CRT,PILER-CR
ATAGGGCTTTCGATCGGTGGCGCGACCCTACCAG
>39.31|4397232|36|NC_019693|CRISPRCasFinder,CRT,PILER-CR
CGTGATGATTCGGGTAGGTTGATTAGTGCAGAAAGC
>39.32|4397305|33|NC_019693|CRISPRCasFinder,CRT,PILER-CR
ACGGAATCCGGAGTGGTTTATGTTGTCAGTCCC
>39.33|4397375|35|NC_019693|CRISPRCasFinder,CRT,PILER-CR
CCTCTGCTAAACGTGATAATGATAATCGCCGTTAT
>39.34|4397447|35|NC_019693|CRISPRCasFinder,CRT,PILER-CR
TCAACGCTGCAACGACTGGCGTCTCACCAGTATCC
>39.35|4397519|35|NC_019693|CRISPRCasFinder,CRT,PILER-CR
ACCGACTGGAACCTCCACCTTTAACCGAATCAGTG
>39.36|4397591|34|NC_019693|CRISPRCasFinder,CRT,PILER-CR
GGGGACTAGGGTTGAGTTGCGTTACGACGGGTTG
>39.37|4397662|34|NC_019693|CRISPRCasFinder,CRT,PILER-CR
CGCCGCTAGGTTCGCTTGACTTGACGGTATAACC
>39.38|4397733|35|NC_019693|CRISPRCasFinder,CRT,PILER-CR
CTAGGGGTGAAGGGTCAGCATTCTGGCAAGGGCGG
>39.39|4397805|34|NC_019693|CRISPRCasFinder,CRT,PILER-CR
TTAGGAGTCAGGTTCACAATGAACAGCTTAACAG
>39.40|4397876|33|NC_019693|CRISPRCasFinder,CRT,PILER-CR
GGAGGATCTCAGGGTTCTCAAACCTGGGGTCAC
>39.41|4397946|41|NC_019693|CRISPRCasFinder,CRT,PILER-CR
ATTGAATTACGAAGCAATGCAAGATTTTAAAAGATTGCTTG
>39.42|4398024|40|NC_019693|CRISPRCasFinder,CRT,PILER-CR
GATATCCCCCTCGTTGTCAATGGCAATCTGGAGGATTTGG
>39.43|4398101|36|NC_019693|CRISPRCasFinder,CRT,PILER-CR
GCCGCTCCGGTCCAGCTTTCCTTCTTCTAGTTTTTC
>39.44|4398174|36|NC_019693|CRISPRCasFinder,CRT,PILER-CR
AAAAACTTTGCCGACTTTAAAGTAGTCCAACATCTG
>39.45|4398247|34|NC_019693|CRISPRCasFinder,CRT,PILER-CR
TGGAGCGAACCGGGGGATTTCCCCGAACAATTAC
>39.46|4398318|36|NC_019693|CRISPRCasFinder,CRT,PILER-CR
TGGAAAGCGTCGCTCTCCCACGATAGGAAATAACGA
>39.47|4398391|33|NC_019693|CRISPRCasFinder,CRT,PILER-CR
AAATATCACTGTACGGTTCTTGCGTACCTCTTG
>39.48|4398461|36|NC_019693|CRISPRCasFinder,CRT,PILER-CR
AGTTAAGACAAACAACACCGTTAGAAACATCATCAA
>39.49|4398534|36|NC_019693|CRISPRCasFinder,CRT,PILER-CR
ACCATAAAAGACTCAACAGGTGTGGCGATCGCAATG
>39.50|4398607|34|NC_019693|CRISPRCasFinder,CRT,PILER-CR
TGTTAGATGCTGCGATAGCTGACGCTTCAAGTGC
>39.51|4398678|37|NC_019693|CRISPRCasFinder,CRT,PILER-CR
GCTACTCCGGTTTGAGTGACCACTAAAGCACCACTAG
>39.52|4398752|36|NC_019693|CRISPRCasFinder,CRT,PILER-CR
ATCCGGTGAGCCTCATCTAACACAACAACCTTATAG
>39.53|4398825|41|NC_019693|CRISPRCasFinder,CRT,PILER-CR
TTAACAGGTTTCCGCAGGGGGAAGATTAGTAGTAAATTTAT
>39.54|4398903|34|NC_019693|CRISPRCasFinder,CRT,PILER-CR
AACGCAGCGGGCGAAAACATCATGAATCATGAAC

CRISPR arrays and Neighbor proteins around NC_019693_39

CRISPR arrays

The CRISPR arrays of NC_019693_39

>merge|NC_019693|39|4394995-4398974|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACATGTCGCAAACGGAGCAGATGGCGCAGGACCTCTTCGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACCGCCTGGGGGTTTAATCATTGGTGCACAGATTAGGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACGGTTGCCGGGTTAATCACTAAAATCGAGGTTGAGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACCAGCGTGATCTTGATTTAGTGATGCAGCAACTCAGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACCAGCGTGATCTTGATTTAGTGATGCAGCAACTCAAGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACTCAGCCATTTCTATCCTCGGGGTGTGTCATTTGAGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACAAGTAGAGTATCCCTTTATCCCGGCTGCTTTACAGGCAGCCCTAGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACGTAGTAAACGGGGATAACTCGGAAGGTTTTCATGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACGACACCCTGATTAAACCGACCGGACTGATTTCCTGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACGAATAAGATCGGCAATCTCGTTTGTACCCATGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACTCTAACCATCGATCATGCCACTGAGCGCCAAAGCGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACTGGGTTTGTCGTACCGGAACACCTGCGAGAACAAGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACCTCATCCTTTTTGGCTTGGATCGCCATTAGGACAACACTAAGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACTGGTTACTCACTTGAACTCCTTAACAAACTTGGTTGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACAGAAGCCATCTCCCATGCGCCATTTCCGAGAATGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACATAATCTTAAAAAGAATATATATAGACAAAAAAATGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACTTTCTCTTTAACAAAATGAACCCAGAAGTTTCCATGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACAGTGAACAGCCTGTGGTCGTTGAGCGTAACGTTCGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACCTATATTAAAGGATTTAGTGTTATTGGCTTATGTAGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACTTAAGCTGTGCGGTCCAGAGCTCCGGATAGCTCTTGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACAATAGTTGGGGTGGTGAAGCTAATTTTGGCAAAGCCTTGTGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACCTCGTTCGGCATCTGTAGGAGTTGCGGGTGCTGCGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACCTCTCTTTCTAATTCTCCAATGTAATTCAAAGCAGTGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACTTTGCCCTGGTGATTGCCTTGGCTAAATCAAACGACGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACGGAAATCTTTGCTGAAAGCCGTGAGGTAAGACCGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACAAGTCAATCATCATCGTCCCCATTTAGTCTCTTCGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACGATTAGCTTATTTGCGGAAGGCTAGAATAGTCCGTGCTTGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACTGTAGCCATCAGGCAAAATGCCGATGGTGGCGCTAGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACATAGGGCTTTCGATCGGTGGCGCGACCCCAGCTTGTTGCCGGGGGCTCATCGGAAAGAGGGGCTGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACATAGGGCTTTCGATCGGTGGCGCGACCCTACCAGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACCGTGATGATTCGGGTAGGTTGATTAGTGCAGAAAGCGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACACGGAATCCGGAGTGGTTTATGTTGTCAGTCCCGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACCCTCTGCTAAACGTGATAATGATAATCGCCGTTATGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACTCAACGCTGCAACGACTGGCGTCTCACCAGTATCCGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACACCGACTGGAACCTCCACCTTTAACCGAATCAGTGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACGGGGACTAGGGTTGAGTTGCGTTACGACGGGTTGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACCGCCGCTAGGTTCGCTTGACTTGACGGTATAACCGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACCTAGGGGTGAAGGGTCAGCATTCTGGCAAGGGCGGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACTTAGGAGTCAGGTTCACAATGAACAGCTTAACAGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACGGAGGATCTCAGGGTTCTCAAACCTGGGGTCACGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACATTGAATTACGAAGCAATGCAAGATTTTAAAAGATTGCTTGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACGATATCCCCCTCGTTGTCAATGGCAATCTGGAGGATTTGGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACGCCGCTCCGGTCCAGCTTTCCTTCTTCTAGTTTTTCGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACAAAAACTTTGCCGACTTTAAAGTAGTCCAACATCTGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACTGGAGCGAACCGGGGGATTTCCCCGAACAATTACGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACTGGAAAGCGTCGCTCTCCCACGATAGGAAATAACGAGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACAAATATCACTGTACGGTTCTTGCGTACCTCTTGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACAGTTAAGACAAACAACACCGTTAGAAACATCATCAAGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACACCATAAAAGACTCAACAGGTGTGGCGATCGCAATGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACTGTTAGATGCTGCGATAGCTGACGCTTCAAGTGCGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACGCTACTCCGGTTTGAGTGACCACTAAAGCACCACTAGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACATCCGGTGAGCCTCATCTAACACAACAACCTTATAGGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACTTAACAGGTTTCCGCAGGGGGAAGATTAGTAGTAAATTTATGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACAACGCAGCGGGCGAAAACATCATGAATCATGAACGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACA

>NC_019693|39|3|4394995-4396987|PILER-CR
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATGTCGCAAACGGAGCAGATGGCGCAGGACCTCTTC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CGCCTGGGGGTTTAATCATTGGTGCACAGATTAGG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GGTTGCCGGGTTAATCACTAAAATCGAGGTTGA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CAGCGTGATCTTGATTTAGTGATGCAGCAACTCA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CAGCGTGATCTTGATTTAGTGATGCAGCAACTCAA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TCAGCCATTTCTATCCTCGGGGTGTGTCATTTGA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AAGTAGAGTATCCCTTTATCCCGGCTGCTTTACAGGCAGCCCTA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GTAGTAAACGGGGATAACTCGGAAGGTTTTCATG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GACACCCTGATTAAACCGACCGGACTGATTTCCT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GAATAAGATCGGCAATCTCGTTTGTACCCAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TCTAACCATCGATCATGCCACTGAGCGCCAAAGCG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGGGTTTGTCGTACCGGAACACCTGCGAGAACAA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTCATCCTTTTTGGCTTGGATCGCCATTAGGACAACACTAA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGGTTACTCACTTGAACTCCTTAACAAACTTGGTT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AGAAGCCATCTCCCATGCGCCATTTCCGAGAAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATAATCTTAAAAAGAATATATATAGACAAAAAAATG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTTCTCTTTAACAAAATGAACCCAGAAGTTTCCAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AGTGAACAGCCTGTGGTCGTTGAGCGTAACGTTC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTATATTAAAGGATTTAGTGTTATTGGCTTATGTA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTAAGCTGTGCGGTCCAGAGCTCCGGATAGCTCTT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AATAGTTGGGGTGGTGAAGCTAATTTTGGCAAAGCCTTGTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTCGTTCGGCATCTGTAGGAGTTGCGGGTGCTGC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTCTCTTTCTAATTCTCCAATGTAATTCAAAGCAGT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTTGCCCTGGTGATTGCCTTGGCTAAATCAAACGAC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GGAAATCTTTGCTGAAAGCCGTGAGGTAAGACCG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AAGTCAATCATCATCGTCCCCATTTAGTCTCTTC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GATTAGCTTATTTGCGGAAGGCTAGAATAGTCCGTGCTT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACTGTAGCCATCAGGCAAAATGCCGATGGTGGCGCTAGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACATAGGGCTTTCGATCGGTGGCGCGACCCCAGCTTGTTGCCGGGGGCTCATCGGAAAGAGGGGCTGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATAGGGCTTTCGATCGGTGGCGCGACCCTACCAG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CGTGATGATTCGGGTAGGTTGATTAGTGCAGAAAGC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ACGGAATCCGGAGTGGTTTATGTTGTCAGTCCC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CCTCTGCTAAACGTGATAATGATAATCGCCGTTAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TCAACGCTGCAACGACTGGCGTCTCACCAGTATCC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ACCGACTGGAACCTCCACCTTTAACCGAATCAGTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GGGGACTAGGGTTGAGTTGCGTTACGACGGGTTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CGCCGCTAGGTTCGCTTGACTTGACGGTATAACC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTAGGGGTGAAGGGTCAGCATTCTGGCAAGGGCGG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTAGGAGTCAGGTTCACAATGAACAGCTTAACAG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GGAGGATCTCAGGGTTCTCAAACCTGGGGTCAC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATTGAATTACGAAGCAATGCAAGATTTTAAAAGATTGCTTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GATATCCCCCTCGTTGTCAATGGCAATCTGGAGGATTTGG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GCCGCTCCGGTCCAGCTTTCCTTCTTCTAGTTTTTC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AAAAACTTTGCCGACTTTAAAGTAGTCCAACATCTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGGAGCGAACCGGGGGATTTCCCCGAACAATTAC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGGAAAGCGTCGCTCTCCCACGATAGGAAATAACGA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AAATATCACTGTACGGTTCTTGCGTACCTCTTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AGTTAAGACAAACAACACCGTTAGAAACATCATCAA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ACCATAAAAGACTCAACAGGTGTGGCGATCGCAATG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGTTAGATGCTGCGATAGCTGACGCTTCAAGTGC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GCTACTCCGGTTTGAGTGACCACTAAAGCACCACTAG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATCCGGTGAGCCTCATCTAACACAACAACCTTATAG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTAACAGGTTTCCGCAGGGGGAAGATTAGTAGTAAATTTAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AACGCAGCGGGCGAAAACATCATGAATCATGAAC


>NC_019693|39|39|4394995-4398974|CRISPRCasFinder
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATGTCGCAAACGGAGCAGATGGCGCAGGACCTCTTC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CGCCTGGGGGTTTAATCATTGGTGCACAGATTAGG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GGTTGCCGGGTTAATCACTAAAATCGAGGTTGA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CAGCGTGATCTTGATTTAGTGATGCAGCAACTCA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CAGCGTGATCTTGATTTAGTGATGCAGCAACTCAA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TCAGCCATTTCTATCCTCGGGGTGTGTCATTTGA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AAGTAGAGTATCCCTTTATCCCGGCTGCTTTACAGGCAGCCCTA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GTAGTAAACGGGGATAACTCGGAAGGTTTTCATG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GACACCCTGATTAAACCGACCGGACTGATTTCCT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GAATAAGATCGGCAATCTCGTTTGTACCCAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TCTAACCATCGATCATGCCACTGAGCGCCAAAGCG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGGGTTTGTCGTACCGGAACACCTGCGAGAACAA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTCATCCTTTTTGGCTTGGATCGCCATTAGGACAACACTAA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGGTTACTCACTTGAACTCCTTAACAAACTTGGTT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AGAAGCCATCTCCCATGCGCCATTTCCGAGAAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATAATCTTAAAAAGAATATATATAGACAAAAAAATG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTTCTCTTTAACAAAATGAACCCAGAAGTTTCCAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AGTGAACAGCCTGTGGTCGTTGAGCGTAACGTTC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTATATTAAAGGATTTAGTGTTATTGGCTTATGTA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTAAGCTGTGCGGTCCAGAGCTCCGGATAGCTCTT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AATAGTTGGGGTGGTGAAGCTAATTTTGGCAAAGCCTTGTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTCGTTCGGCATCTGTAGGAGTTGCGGGTGCTGC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTCTCTTTCTAATTCTCCAATGTAATTCAAAGCAGT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTTGCCCTGGTGATTGCCTTGGCTAAATCAAACGAC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GGAAATCTTTGCTGAAAGCCGTGAGGTAAGACCG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AAGTCAATCATCATCGTCCCCATTTAGTCTCTTC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GATTAGCTTATTTGCGGAAGGCTAGAATAGTCCGTGCTT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGTAGCCATCAGGCAAAATGCCGATGGTGGCGCTA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATAGGGCTTTCGATCGGTGGCGCGACCCCAGCTTGTTGCCGGGGGCTCATCGGAAAGAGGGGCT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATAGGGCTTTCGATCGGTGGCGCGACCCTACCAG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CGTGATGATTCGGGTAGGTTGATTAGTGCAGAAAGC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ACGGAATCCGGAGTGGTTTATGTTGTCAGTCCC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CCTCTGCTAAACGTGATAATGATAATCGCCGTTAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TCAACGCTGCAACGACTGGCGTCTCACCAGTATCC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ACCGACTGGAACCTCCACCTTTAACCGAATCAGTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GGGGACTAGGGTTGAGTTGCGTTACGACGGGTTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CGCCGCTAGGTTCGCTTGACTTGACGGTATAACC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTAGGGGTGAAGGGTCAGCATTCTGGCAAGGGCGG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTAGGAGTCAGGTTCACAATGAACAGCTTAACAG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GGAGGATCTCAGGGTTCTCAAACCTGGGGTCAC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATTGAATTACGAAGCAATGCAAGATTTTAAAAGATTGCTTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GATATCCCCCTCGTTGTCAATGGCAATCTGGAGGATTTGG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GCCGCTCCGGTCCAGCTTTCCTTCTTCTAGTTTTTC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AAAAACTTTGCCGACTTTAAAGTAGTCCAACATCTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGGAGCGAACCGGGGGATTTCCCCGAACAATTAC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGGAAAGCGTCGCTCTCCCACGATAGGAAATAACGA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AAATATCACTGTACGGTTCTTGCGTACCTCTTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AGTTAAGACAAACAACACCGTTAGAAACATCATCAA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ACCATAAAAGACTCAACAGGTGTGGCGATCGCAATG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGTTAGATGCTGCGATAGCTGACGCTTCAAGTGC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GCTACTCCGGTTTGAGTGACCACTAAAGCACCACTAG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATCCGGTGAGCCTCATCTAACACAACAACCTTATAG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTAACAGGTTTCCGCAGGGGGAAGATTAGTAGTAAATTTAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AACGCAGCGGGCGAAAACATCATGAATCATGAAC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACA

>NC_019693|39|2|4394995-4398973|CRT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATGTCGCAAACGGAGCAGATGGCGCAGGACCTCTTC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CGCCTGGGGGTTTAATCATTGGTGCACAGATTAGG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GGTTGCCGGGTTAATCACTAAAATCGAGGTTGA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CAGCGTGATCTTGATTTAGTGATGCAGCAACTCA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CAGCGTGATCTTGATTTAGTGATGCAGCAACTCAA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TCAGCCATTTCTATCCTCGGGGTGTGTCATTTGA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AAGTAGAGTATCCCTTTATCCCGGCTGCTTTACAGGCAGCCCTA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GTAGTAAACGGGGATAACTCGGAAGGTTTTCATG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GACACCCTGATTAAACCGACCGGACTGATTTCCT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GAATAAGATCGGCAATCTCGTTTGTACCCAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TCTAACCATCGATCATGCCACTGAGCGCCAAAGCG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGGGTTTGTCGTACCGGAACACCTGCGAGAACAA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTCATCCTTTTTGGCTTGGATCGCCATTAGGACAACACTAA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGGTTACTCACTTGAACTCCTTAACAAACTTGGTT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AGAAGCCATCTCCCATGCGCCATTTCCGAGAAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATAATCTTAAAAAGAATATATATAGACAAAAAAATG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTTCTCTTTAACAAAATGAACCCAGAAGTTTCCAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AGTGAACAGCCTGTGGTCGTTGAGCGTAACGTTC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTATATTAAAGGATTTAGTGTTATTGGCTTATGTA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTAAGCTGTGCGGTCCAGAGCTCCGGATAGCTCTT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AATAGTTGGGGTGGTGAAGCTAATTTTGGCAAAGCCTTGTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTCGTTCGGCATCTGTAGGAGTTGCGGGTGCTGC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTCTCTTTCTAATTCTCCAATGTAATTCAAAGCAGT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTTGCCCTGGTGATTGCCTTGGCTAAATCAAACGAC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GGAAATCTTTGCTGAAAGCCGTGAGGTAAGACCG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AAGTCAATCATCATCGTCCCCATTTAGTCTCTTC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GATTAGCTTATTTGCGGAAGGCTAGAATAGTCCGTGCTT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGTAGCCATCAGGCAAAATGCCGATGGTGGCGCTA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATAGGGCTTTCGATCGGTGGCGCGACCCCAGCTTGTTGCCGGGGGCTCATCGGAAAGAGGGGCT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATAGGGCTTTCGATCGGTGGCGCGACCCTACCAG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CGTGATGATTCGGGTAGGTTGATTAGTGCAGAAAGC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ACGGAATCCGGAGTGGTTTATGTTGTCAGTCCC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CCTCTGCTAAACGTGATAATGATAATCGCCGTTAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TCAACGCTGCAACGACTGGCGTCTCACCAGTATCC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ACCGACTGGAACCTCCACCTTTAACCGAATCAGTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GGGGACTAGGGTTGAGTTGCGTTACGACGGGTTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CGCCGCTAGGTTCGCTTGACTTGACGGTATAACC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTAGGGGTGAAGGGTCAGCATTCTGGCAAGGGCGG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTAGGAGTCAGGTTCACAATGAACAGCTTAACAG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GGAGGATCTCAGGGTTCTCAAACCTGGGGTCAC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATTGAATTACGAAGCAATGCAAGATTTTAAAAGATTGCTTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GATATCCCCCTCGTTGTCAATGGCAATCTGGAGGATTTGG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GCCGCTCCGGTCCAGCTTTCCTTCTTCTAGTTTTTC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AAAAACTTTGCCGACTTTAAAGTAGTCCAACATCTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGGAGCGAACCGGGGGATTTCCCCGAACAATTAC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGGAAAGCGTCGCTCTCCCACGATAGGAAATAACGA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AAATATCACTGTACGGTTCTTGCGTACCTCTTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AGTTAAGACAAACAACACCGTTAGAAACATCATCAA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ACCATAAAAGACTCAACAGGTGTGGCGATCGCAATG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGTTAGATGCTGCGATAGCTGACGCTTCAAGTGC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GCTACTCCGGTTTGAGTGACCACTAAAGCACCACTAG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATCCGGTGAGCCTCATCTAACACAACAACCTTATAG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTAACAGGTTTCCGCAGGGGGAAGATTAGTAGTAAATTTAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AACGCAGCGGGCGAAAACATCATGAATCATGAAC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC

>NC_019693|39|4|4397124-4398973|PILER-CR
	ATGTCGCAAACGGAGCAGATGGCGCAGGACCTCTTC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CGCCTGGGGGTTTAATCATTGGTGCACAGATTAGG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GGTTGCCGGGTTAATCACTAAAATCGAGGTTGA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CAGCGTGATCTTGATTTAGTGATGCAGCAACTCA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CAGCGTGATCTTGATTTAGTGATGCAGCAACTCAA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TCAGCCATTTCTATCCTCGGGGTGTGTCATTTGA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AAGTAGAGTATCCCTTTATCCCGGCTGCTTTACAGGCAGCCCTA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GTAGTAAACGGGGATAACTCGGAAGGTTTTCATG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GACACCCTGATTAAACCGACCGGACTGATTTCCT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GAATAAGATCGGCAATCTCGTTTGTACCCAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TCTAACCATCGATCATGCCACTGAGCGCCAAAGCG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGGGTTTGTCGTACCGGAACACCTGCGAGAACAA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTCATCCTTTTTGGCTTGGATCGCCATTAGGACAACACTAA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGGTTACTCACTTGAACTCCTTAACAAACTTGGTT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AGAAGCCATCTCCCATGCGCCATTTCCGAGAAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATAATCTTAAAAAGAATATATATAGACAAAAAAATG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTTCTCTTTAACAAAATGAACCCAGAAGTTTCCAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AGTGAACAGCCTGTGGTCGTTGAGCGTAACGTTC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTATATTAAAGGATTTAGTGTTATTGGCTTATGTA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTAAGCTGTGCGGTCCAGAGCTCCGGATAGCTCTT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AATAGTTGGGGTGGTGAAGCTAATTTTGGCAAAGCCTTGTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTCGTTCGGCATCTGTAGGAGTTGCGGGTGCTGC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTCTCTTTCTAATTCTCCAATGTAATTCAAAGCAGT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTTGCCCTGGTGATTGCCTTGGCTAAATCAAACGAC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GGAAATCTTTGCTGAAAGCCGTGAGGTAAGACCG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AAGTCAATCATCATCGTCCCCATTTAGTCTCTTC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GATTAGCTTATTTGCGGAAGGCTAGAATAGTCCGTGCTT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACTGTAGCCATCAGGCAAAATGCCGATGGTGGCGCTAGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAACATAGGGCTTTCGATCGGTGGCGCGACCCCAGCTTGTTGCCGGGGGCTCATCGGAAAGAGGGGCTGTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATAGGGCTTTCGATCGGTGGCGCGACCCTACCAG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CGTGATGATTCGGGTAGGTTGATTAGTGCAGAAAGC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ACGGAATCCGGAGTGGTTTATGTTGTCAGTCCC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CCTCTGCTAAACGTGATAATGATAATCGCCGTTAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TCAACGCTGCAACGACTGGCGTCTCACCAGTATCC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ACCGACTGGAACCTCCACCTTTAACCGAATCAGTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GGGGACTAGGGTTGAGTTGCGTTACGACGGGTTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CGCCGCTAGGTTCGCTTGACTTGACGGTATAACC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	CTAGGGGTGAAGGGTCAGCATTCTGGCAAGGGCGG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTAGGAGTCAGGTTCACAATGAACAGCTTAACAG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GGAGGATCTCAGGGTTCTCAAACCTGGGGTCAC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATTGAATTACGAAGCAATGCAAGATTTTAAAAGATTGCTTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GATATCCCCCTCGTTGTCAATGGCAATCTGGAGGATTTGG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GCCGCTCCGGTCCAGCTTTCCTTCTTCTAGTTTTTC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AAAAACTTTGCCGACTTTAAAGTAGTCCAACATCTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGGAGCGAACCGGGGGATTTCCCCGAACAATTAC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGGAAAGCGTCGCTCTCCCACGATAGGAAATAACGA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AAATATCACTGTACGGTTCTTGCGTACCTCTTG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AGTTAAGACAAACAACACCGTTAGAAACATCATCAA
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ACCATAAAAGACTCAACAGGTGTGGCGATCGCAATG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TGTTAGATGCTGCGATAGCTGACGCTTCAAGTGC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	GCTACTCCGGTTTGAGTGACCACTAAAGCACCACTAG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	ATCCGGTGAGCCTCATCTAACACAACAACCTTATAG
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	TTAACAGGTTTCCGCAGGGGGAAGATTAGTAGTAAATTTAT
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC	AACGCAGCGGGCGAAAACATCATGAATCATGAAC
GTCTCAATAACCCCTAATCCCTTTCAGGGATTGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015149696.1|4384016_4384244_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044197345.1|4399680_4400196_-|damage-inducible-protein-DinB	unknown	unknown	gnl|CDD|225200
NC_019693.1|WP_015149699.1|4385207_4385399_-|YgiT-type-zinc-finger-protein	unknown	unknown	gnl|CDD|240606
NC_019693.1|WP_015149697.1|4384233_4384476_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149701.1|4388294_4392884_-|glutamate-synthase-large-subunit	unknown	unknown	gnl|CDD|236968
NC_019693.1|WP_015149706.1|4401019_4406506_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|274362
NC_019693.1|WP_015149698.1|4384563_4385073_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149704.1|4399001_4399376_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149709.1|4411968_4412565_-|peroxiredoxin	unknown	unknown	gnl|CDD|239313
NC_019693.1|WP_015149694.1|4381900_4382128_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823876.1|4400232_4400424_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149695.1|4382577_4383573_-|hypothetical-protein	unknown	unknown	gnl|CDD|366612
NC_019693.1|WP_015149711.1|4413686_4418000_-|response-regulator	unknown	unknown	gnl|CDD|236848
NC_019693.1|WP_044194328.1|4408777_4410535_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209
NC_019693.1|WP_015149708.1|4411242_4411803_-|redoxin-domain-containing-protein	unknown	unknown	gnl|CDD|224146
NC_019693.1|WP_015149710.1|4413261_4413690_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149700.1|4385623_4388194_-|DEAD/DEAH-box-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl|CDD|224125
NC_019693.1|WP_015149702.1|4393733_4394081_+|DUF433-domain-containing-protein	unknown	unknown	gnl|CDD|225291
NC_019693.1|WP_015149707.1|4406502_4408338_+|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|236645
NC_019693.1|WP_015149703.1|4394084_4394426_+|hypothetical-protein	unknown	unknown	gnl|CDD|375906

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_015149700.1|4385623_4388194_-|DEAD/DEAH-box-helicase	DinG	COG1199_DinG_CAS-IV-A	1.2e-12	41.6	0.7
NC_019693.1|WP_044194328.1|4408777_4410535_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	7.5e-46	151.1	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_044197345.1|4399680_4400196_-|damage-inducible-protein-DinB	gnl|CDD|225200	COG2318, DinB, Uncharacterized protein conserved in bacteria [Function unknown].	4.3785e-43
NC_019693.1|WP_015149699.1|4385207_4385399_-|YgiT-type-zinc-finger-protein	gnl|CDD|240606	cd12870, MqsA, antitoxin MqsA for MqsR toxin. This family includes domains similar to the antitoxin MqsA that binds motility quorum-sensing regulator MqsR, a toxin that is highly upregulated in persisters (dormant cells found in biofilms that are a source of antibiotic resistance), thus forming a unique toxin:antitoxin (TA) pair. MqsA neutralizes MsqR toxicity. It binds its own promoter as well as those of genes important for E. coli physiology, such as mcbR and spy. It also binds zinc and has been shown to coordinate DNA via its C-terminal domain. This family also includes the B. subtilis YokU protein, which is functionally uncharacterized.	4.37541e-08
NC_019693.1|WP_015149702.1|4393733_4394081_+|DUF433-domain-containing-protein	gnl|CDD|225291	COG2442, COG2442, Uncharacterized conserved protein [Function unknown].	1.39407e-16
NC_019693.1|WP_015149701.1|4388294_4392884_-|glutamate-synthase-large-subunit	gnl|CDD|236968	PRK11750, gltB, glutamate synthase subunit alpha; Provisional.	0
NC_019693.1|WP_015149706.1|4401019_4406506_+|PAS-domain-S-box-protein	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	9.04401e-79
NC_019693.1|WP_015149703.1|4394084_4394426_+|hypothetical-protein	gnl|CDD|375906	pfam18480, DUF5615, Domain of unknown function (DUF5615). This is a domain of unknown function found in potential toxin-antitoxin system component.	1.00021e-24
NC_019693.1|WP_015149709.1|4411968_4412565_-|peroxiredoxin	gnl|CDD|239313	cd03015, PRX_Typ2cys, Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. The functional unit of typical 2-cys PRX is a homodimer. A unique intermolecular redox-active disulfide center is utilized for its activity. Upon reaction with peroxides, its peroxidatic cysteine is oxidized into a sulfenic acid intermediate which is resolved by bonding with the resolving cysteine from the other subunit of the homodimer. This intermolecular disulfide bond is then reduced by thioredoxin, tryparedoxin or AhpF. Typical 2-cys PRXs, like 1-cys PRXs, form decamers which are stabilized by reduction of the active site cysteine. Typical 2-cys PRX interacts through beta strands at one edge of the monomer (B-type interface) to form the functional homodimer, and uses an A-type interface (similar to the dimeric interface in atypical 2-cys PRX and PRX5) at the opposite end of the monomer to form the stable decameric (pentamer of dimers) structure.	9.80971e-115
NC_019693.1|WP_015149695.1|4382577_4383573_-|hypothetical-protein	gnl|CDD|366612	pfam01393, Chromo_shadow, Chromo shadow domain. This domain is distantly related to pfam00385. This domain is always found in association with a chromo domain.	0.00850528
NC_019693.1|WP_015149711.1|4413686_4418000_-|response-regulator	gnl|CDD|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	4.82802e-109
NC_019693.1|WP_044194328.1|4408777_4410535_-|group-II-intron-reverse-transcriptase/maturase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	6.87539e-123
NC_019693.1|WP_015149700.1|4385623_4388194_-|DEAD/DEAH-box-helicase	gnl|CDD|224125	COG1204, COG1204, Superfamily II helicase [General function prediction only].	1.08474e-44
NC_019693.1|WP_015149707.1|4406502_4408338_+|EAL-domain-containing-protein	gnl|CDD|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	1.90464e-120
NC_019693.1|WP_015149708.1|4411242_4411803_-|redoxin-domain-containing-protein	gnl|CDD|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	7.05157e-25

Protein sequences

>NC_019693.1|WP_015149703.1|4394084_4394426_+|hypothetical-protein
MARFYVDENFPLPVVELLRNLGHDLLTVREAGKANLGIPDAEVLAFSIECDRAVLTGNRRDYIKLHRLQPNHAGIVVCTEDPNFERLAQRIDQAISDEETLQGKLIRVHRPLE
>NC_019693.1|WP_015149702.1|4393733_4394081_+|DUF433-domain-containing-protein
MTIAELRTQLLALTPAEKAEAIQTLIQTLDNGSLGITKTPGVCGGDACIANTRIPLWSVINYRRLGAGDRMILEAFPYLTAADLVNVWAYAEAHPEEIERAIQENEEIMQGDEED
>NC_019693.1|WP_015149701.1|4388294_4392884_-|glutamate-synthase-large-subunit
MNHQKLPQKQGLYDPQFEHDACGVGFIVHQKGQKSHSIVEQALTILLNLDHRGACGCENNTGDGAGILIQVPDAFLKKVAAAENISLPNAGEYGVGNIYCSQDPAIRQQSRQQFEKIVAEEGQKVLGWRDVPTDHSSLGNTAKSSEPFISQVFIQRSANITDDLAFDRKLYVIRKRAEREIHISQLDSFWYVCSLSCRTLVYKGMLMPVQVGDYFPELHDETMESALALVHSRFSTNTFPSWERSHPYRYIAHNGEINTLRGNINWMHARESLFESELFGEDLKKLHPVIDLEGSDSAIFDNALEMLFLSGRSLPHAVMMMIPEPWTAHESMSPEKKAFYKYHSCLMEPWDGPASIAFTDGTMMGAVLDRNGLRPSRYYVTKDDLVIMASEAGVLPIEPERVAYKGRLQPGRMFLVDMKQGRIISDEEIKTQIVSEHPYQQWIDENLVALSQLKDAPQLREMDPVPLIQRQMAFGYTFEELRLLMTPMATNGVEAIGSMGTDTPLAVLSDRPKLLYDYFQQLFAQVTNPPIDSIREEIVTSAETTIGAERNLLKPTAKSCNLIELKTPVLTDEELAKLKAVNEGAFKSTTIPMLFDPTTGVKGLEAALEAIFAQATQAIATGTNILILSDRGMNREKVAIPALLAVAGLHHHLIRQGTRTQVGLVLESGEPREVHHFAALIGYGCGAINPYLAFETIDDMIREKLLVNVEYKTAVKNYIKAVTKGVVKIASKIGISTIQSYRGAQIFEAIGLNQSVISRYFTWTASRIEGVDLEAIANETIMRHSHAFPDRDANGHTLDVGGEYQWRKDGEAHLLSPEIIHALQQATREGNYELYKKYAAKVNEQNQKFFTLRGLLEFKAQQPIPLEEVEPIESIMKRFKTGAMSYGSISKEAHESLAIAMNRVGGKSNTGEGGEDPDRYTWTNERGDSKNSAIKQVASGRFGVTSLYLSQAKEIQIKMAQGAKPGEGGQLPGLKVYPWIAKVRHSTPGVGLISPPPHHDIYSIEDLAELIHDLKNANRNARVNVKLVSEVGVGTIAAGVAKAHADVVLVSGFDGGTGASPQTSIKHAGLPWELGLAETHQTLVLNNLRSRIVVETDGQMKTGRDVAIAALLGAEEYGFSTAPLVTLGCIMMRVCHKNTCPVGIATQNPELRAKFMGDPEYAANFMRFIAQELREIMAQLGFRTLTEMVGRTDLLEPKKAVDHWKAKGIDLSNILYQPQVGPEVGRYCQIPQDHGLEKSLDMTVLLDLCKGAIDNGEKVKATLPITNINRVVGTILGNEITKKHWDGLPDGTIHLHFQGSAGQSFGAFVPKGVTLELEGDGNDYIGKGLSGGKIIVYPSKKSTLVPHENIIAGNVALYGATSGELYLSGIAGERFAVRNSGVHAVVEGVGDHGCEYMTGGKVVVIGPAGRNFAAGMSGGVAYILDEAGDFATRCNTQMADMEKLEEPSEIAIVREMIQKHADYTNSPKAAAVLANWEEMVPKFVKVMPRDYKRVLQALESALASGLSGDDALDAAFEQNARDVARIGGS
>NC_019693.1|WP_015149700.1|4385623_4388194_-|DEAD/DEAH-box-helicase
MVDFKKRLGFRAIEKKINPVEIYDELDRRSETGPLRPVQQQVLAEWWSNRKEDKDLILKLHTGQGKTLIGLLMLQSQLNQKKGPCLYVCPNKYLVEQTCQEAEKFGIGYVKIGPDNSLPEEFLSSEKILITHIQKFFNGKSIFGIGGKFVTVNTIILDDSHACIDFIKKSFKIVLKKEHELYLKILNLFKQDLNKQGEGRLFEIQNGSGENTSIPVPYWSWEDKKQEIIAFLGEYNEDKDITFTWPLIKDRIGNCQCIISGREIEISPFVSLIHEFRSFGQARHRILMSATTQNDSFFIKGFGLSVESVKNPLTHKYEKWWGEKMILIPSLIRDDLDKNKIIPRFAQSKETREVGIVVITSSFKKAKLYENNGAVICKTEDIFERVNQLKNGHDYSKTIVFVNRYDGIDLPDDSCRLLIMDSLPYANSLSDKYEEECRSNSDFINIQIAQRIEQGMGRSVRGEKDYSVIILLGKDLIKFVKSSLTNKFFSSQTRKQIEIGLEIANIVNEDNSEQPQSPKNQSLHILQELMKQCVARDEGWKEFYREKMNDVNQDENFYQSQEIDILSLEKKAADSFYKNDAESAVKYIQQLIDSYCQDRTDDDDDDEKAWYLQILARYKYTLSKVDANKIQKSAYQKNQRLLKPQDGITYEKTNYINDGRIKKIKTWIMSDPSYEQLMLKVEAMLDDLSFGQPSEKFERALQDLGKAIGFQSKRPDREFKTGPDNLWCVENNDYFIFECKSEVDDNRREIIKTETGQMNNHCAWFEQEYKTARVKTILIIPTNKVASNANFTHEVTIMKRNKLESLKNSVKGFFKEIKDYKIPELSDAKIQEWLLVHKLDLKSLKTHYTESYYPKK
>NC_019693.1|WP_015149699.1|4385207_4385399_-|YgiT-type-zinc-finger-protein
MTNNFPQETLIEKRVTYTLEMNGKFFMIENVPARVCEKTGESFFSPETVVRIQQMIWGQEKPK
>NC_019693.1|WP_015149698.1|4384563_4385073_-|hypothetical-protein
MQILAITEVDFYKIDRCRRVISHDCAQKFAAIDLGVPLGCYGLSWRSDILEPIIVRSPDRLTVWIGVDQQLAAISLDEGRIIVALPLTDYLVQIVAIADVIAVLTQEKVLLFNPGGSIRFSDDLPDQGIGMTVEGENLVIQMLEGESLTLNPMRGYFQSMAASMTRRSP
>NC_019693.1|WP_015149697.1|4384233_4384476_-|hypothetical-protein
MSITELFPIVQNLSPAEKIRLLEFLQAEIEQSQSASESSESMHPRLHRKNDILVIETVPLNHIDFNRLIRENQINTCNGN
>NC_019693.1|WP_015149696.1|4384016_4384244_-|hypothetical-protein
METKTITIRVNAEAARIFENASEEQQRKLEVLLSLKLTEATRSTQSLEELMSDISSKAQKRGLTPEILGAILNDE
>NC_019693.1|WP_015149695.1|4382577_4383573_-|hypothetical-protein
MSKNIRLFSNYVQRENQTTNYCLLILKLLYEENPKFLSEVLSTLLGERLSGAVGVKFSQQNRGKKSVPDGKISQEAFSIVIETKRDNRFNLEQLSRHLEPMKEEAGIQVLMALGNFEWEEPNPEAFQDIDRLAEEMGVAFAAVSFEQFLQALKLSYLPKNLVDAIADLEEYMNEENLLPSWKYHLDVVNCRVSFDDVLQHQIYVCPATDGSYNHRRSLYFGMYRNKRVEQVGKIEAVVDLESEETFSIKWKNIEKSDLELVEMARSRRSQIDDSWYPARVFILADLHSTDFVKASPGGMQSSKQYFDISQLNIMNAEDLARKLTGKSWENY
>NC_019693.1|WP_015149694.1|4381900_4382128_-|hypothetical-protein
METKTITIRVNAEAARIFENASEEQQRKLEVLLSLKLTEATRSTQSLEELMSDISSKAQERGLTPEILDSILNND
>NC_019693.1|WP_015149704.1|4399001_4399376_+|hypothetical-protein
MNSSFTRSELRKVAKYYRLVSWAILASLGVNLLLLLSASSPSTQLIVLILLIVVGIFQFYVLYNLGKSLNLPGALIILIVLSAFVPLLALALLAYMHDRAMKLFKSAGVKVGFMGANPASIKDE
>NC_019693.1|WP_044197345.1|4399680_4400196_-|damage-inducible-protein-DinB
MHNRNTYQLMAEYNCWMNQNIYQVCESIPDEQRKQDRGAFFKSIHGTLNHLLYGDKVWMGRFTNQPFSGTSLSQELYADFAELRAEREQTDEQILDWSKTLDPDWLNQPFEYVSQSGQKRPVMPAWILVTHLFNHQTHHRGQVTTLIKQLGYEPGVTDIPWMPGVSGLGSE
>NC_019693.1|WP_156823876.1|4400232_4400424_+|hypothetical-protein
MKLDKTAARRRRSHLNPDPAIAILNEFDLKKTSKMLVLTHWLRQRTPKMYDNNCGKRYILNQL
>NC_019693.1|WP_015149706.1|4401019_4406506_+|PAS-domain-S-box-protein
MDIIRGQYEPVLVTLSLIIGAIAAYTALDLAGRVNPNSSMRSRLIWSVGGAVAMGTGIWSMHFIAMLALRLPVPTAYNMPLTLLSWVDAIVASALAMLLYNRQQLRVGLLVGGGVVMGLAIASMHYLGMAAVQVPARVEYNPWGVTLSVAVAIFASTAALGLAFQVRNSLSPHREWVKLGSAGIMGVAIAGMHYTGMWATCFAAISHPEAILIEGADQSWLAMQIGLGTLILLIGTLITSLVDRRYQSHLLREQALQESETRFRTLVENMSVGVLLLDKNGTIVLSNPLASELLDVPESELQGKNAFEFNWQILSLDGTILIQEQHPLQMAVAQGQPVQNQVTGICRWGKKDTVWLLLNMDPQLDASGQVERVVCTFSNISDRKQSEDEIRLLLDTNQAIRHAPDLESALASVLRCICMTINWDVAEAWLPDENQQFLTYRPGWYYPEPDVEAFRLQREPVIYRVGEGLPGRVWESRQPEWIENLTEETDFLADAVMAVKQGLKASFAVPIIRGNGILAVLTFFKRTESPRDDRAIALVGAVATQLGSSIGQKVAEAALSESERRLQLALEGSDLGIWDWQIPTGKTYFDPQWKGMLGYEVEEIGNQYQIWEDLLHREDRKPTLRALQDHLAGILPVYERELRMKSKSGEWKWILSRGKVVERDPSGIPLRMSGTHKDITPRKAAEAALEESQRRYQTLAEASPVCIFHTDAQGNCLYVNQRWTELTGLSLERAIGKSWIANLHPDDFKRVQSEWFLAAETRMPFKSEYRFVRPDGIVVWAIGQAIAEIGEDGLVKGYLGTITDISERKRAEIALQQQLKRERLVSSIQERIRSSLDLEEVLETAVKEVRGFLATDRILIYRFSPDWSGVIAVESVGSDWMSVKGIEIEDRCFIETHIPLYAQGRIRAIDNIHTTGLSECHVELLSQFAVQANLVVPLRQGEQLWGLLIAHHCSGERQWHESEIESLRQLSVQLSIAIQQCTLFEQAKTELLERKRAEDALRESEERFKLAVSGTNDGIWDWDLKNDQIYYSPVWMQILGYEEGELPYRVSTWFNKVHPDDLSVAMQTLQDHVQGQNPLYYYHTHRMERKDKSWIWVEVKGKCIRNEAGEAYRLTGTLTDITERKQAEEALQESVQRERALSQVIQRMRETLDLETIFSATTRELRQVLKCDRVLVHHFHDDWRGEVVAESTGPEWISLMDNIQDLPETAVNLNGGDADSLEDPEVALEDWYMQSARTEHWNSGLTYLAVEDVYSAGFDEAYLNILEQFQAKAYIIVPIFSGNKLWGLLASYQNSGSRHWKEAEIKVVVQIGNQLGVALQQAELLEKTQRQSHALQKAALAADAANRAKSEFLANMSHELRTPLNAILGFTQVMARDASLKPENHEHLKIINRAGGHLLALINDVLEMSKIEAGRMSFNSVNFDLLNLLKSLNEMFQIKAESKQLQIIFEGWDELPQFVKTDESKLRQVLINIVGNAIKFTETGHVILRIEVTDAPTGVNPDPGDFSDSGNPGKFLYFEIEDTGPGIAPEEMGKLFEPFGQTETGRKSQQGTGLGLPISRKFVQLMGGDIQVTSIVGQGTVFAFAVAIAPSSEGEVQTRQTKRRAVAIAPQAQANESRILVVDDAFESRLLLKTILKSLGFQVQEAENGQGAIAVYQSWKPHLILMDMQMPVMDGYEATRHIKSTAQGQKTTIVALTASAFEEERKMILDAGCDDFIRKPFLEELLLETIGRYLNIDYIFEDLSPDQNRPQPDSPTSQYSLSPEALKVMPESWINQLSDAATQCSDDLILRLLEEIPPDLAPLSQALAELAHNYQFDLIEELTQQEGQ
>NC_019693.1|WP_015149707.1|4406502_4408338_+|EAL-domain-containing-protein
MNTEPLQTLQKDILIVDDTQDNLRYLATILTEEGYKVRKALNGQMALKACRVVVPDLILLDIMMPDMSGYQVCEILKENEATREIPVIFLSALDDAFDKVKAFNVGGIDYISKPFQLEEVLARIQTQLLRRDAELKIQQLNAELETRVQERTLQLEESNQELVQEIKERKQLQERLLHLALHDPLTNLPNRALFMERLAQAIAFRKANPDYQFAVLFLDCDRFKVVNDSLGHLVGDELLIAIAKRLQSALRQEDTLARLGGDEFAVLVEELPTLDRAQTIADRILHSLTEPFQLSRYEVFINASIGITLSSFYHEKPEYLLRDADTAMYRAKALGKGQYYLFDPGMHDEALNRLQLENDLRRAVERLEFKVYYQPIISLTTGRIYGFEALVRWQHPTRGFISPLDFIPIAEETGLIANIDLWVLGETVRQLQAWQHQNLINDTVTCSVNLSARHFLQFSFIQHLRELLESTQINPQMIKLEITESAIANKNQATLDILHQIRDCQIELSIDDFGTGYSSLSYLEEFPVNVLKIDRSFIKRIDGQEHQCGLVPGIIGIAHTMGMIAIAEGVETPIQLEKLRGLGCDFAQGYLFSKPLDPEAIGELLARSPQW
>NC_019693.1|WP_044194328.1|4408777_4410535_-|group-II-intron-reverse-transcriptase/maturase
MTVAMNTVKTSLKTTETWNAIPWTKVQRKVFKLQKRIFQAAKSGQDAKARRLQKLLTSSYYARLLAVRKVTQDNQGKKTAGIDGVKSLKPKQRLELAKDLGKHSKAKALRRVWIPKPGRDEKRPLGIPIIRDRAEQALVKQALEPEWEARFEGTSYGFRPGRSAHDAIGRIYASINQGSYYVLDADITKCFDKINHEYLLSKLDCCLQHRRQIKQWLKAGVVDNGIFEDTESGTPQGGVISPLLANIALDGMARLIEELYPKRKGQKVKATLIRYADDFVVISPEIEIINQCKIALENWLKFVGLELKPEKTKICHTLREIEVNGEKVTPGFDFLGFTIRQYPVGKYKSGKTGGANSRLIGHKTHIKPSAKAIKAHSEALKGVIKNHKTAPQAALISRLNPIIRGWSNYYSGVVSMETFNQMDHNIWQQLRAWTVSRCGQANLEKLRKYFHKVTVKIGNGKERNEKWLFQAKDGLSLWKHSYTQITRHTLVKPEASPYDGNWSYWATRRGTSLEVPMRVAKLLKKHSGRCSRCGQYFAMEDLMEVDHIQPLSMGGKDEYRNLQLLHRHCHDKKTAEDMQNVKSYQ
>NC_019693.1|WP_015149708.1|4411242_4411803_-|redoxin-domain-containing-protein
MLTSTDFRGLLNQRFFNNFLPVPALNKLYPEVCPPDFQLPHVNGEGSIRISEYREKQPVILYFTRIFTEKQYCPLCFPHIKAMNTAYEQFVEAGAEVLLITSTDERQSQIVIRDLGLKMPVMCDPSCLVFRAYGTGQALGAPLPAQYLLDIEGKLRFKHLFSFLEPNAQVSRLLEQLQQLPQPAGV
>NC_019693.1|WP_015149709.1|4411968_4412565_-|peroxiredoxin
MTEGCIRVGQQAPDFTATAVVDQEFKTIKLSDYRGKYVVLFFYPLDFTFVCPTEITAFSDSHGKFSQLNTEVLGVSVDSEFSHLAWIQTDRKSGGLGDLNYPLVSDIKKEISSAYNVLDPEAGIALRGLFIIDKDGVIQHATINNLAFGRNVEETLRILQAIQHVQTHPDEVCPAGWQPGAKTMNPDPKKSKEFFAAI
>NC_019693.1|WP_015149710.1|4413261_4413690_+|hypothetical-protein
MQLPTRPLIAPLFAVLLAAVAPHRLHAEVVQLQPQFNSDPIQLQGTSGGVQKSDCGSISEQPSQTLEVGQQFPYLRLRVESAGEPTLLIEGPTGRFCVLADSTVGEQPEMSGLWTVGTYQIYIGDLAGEQHNYTLSISENPN
>NC_019693.1|WP_015149711.1|4413686_4418000_-|response-regulator
MKLRKKILIIVGTTLLGLNVVLYATASSILLGDFKDLEQKVVHQDAIRGLQSLQQTLNELKSIARYHAEWDDTYSFITPGDPNYVNSNFGNETFVQLKLNLLLILDEQRRPVFSKAFDFQEKVEIPMPEVIQDLASAYQQQVEKKFTETGHHNHPLSGIVLLPQGPALIAAQSILTSQGEGPYRGTLWVGRFLNEAEIDRLAELTQLSLNVYPISALPPELDGVRTELEGASPSPTDSEPFQGMDLGGPGRSPIVVKALSEREMAAYTPIPAISSNTPLLLQINHNREIYAKGKISVRYFIGSLLGVSLGFSGLTLLLFEKLVLSRLTVLSRKVERIGDKGDLSMRVKIAGHDELSSLGVTINGMLKALQESQYKLQESEERYRLMAENSTDMISRHTPKGKFIYVSPACHSLLGYEPDELIGCNLYDFFHPEDAKTLAKSYLAMVKGQVSYTVSYRIRHKYGHYLWFESTSRTVRNPQTDDIEELVAISRDITERHQTDEELRESEASIRALYKITSSRKLSFEQRLQRLLIMGKRRFGLSVAILSRIKRDRYEIIAVQSPDDTLQPGDRFPLSQTYCRETLRLKEPLYFESVSVTRWHSKPTQTAFPQEAYIGTRVIVGGKIYGTLSFSSSTPLGRPFKAVDKELLKLMAQWIGSEIERRAAAADLARARDEALAATRAKSEFLATMSHEIRTPMNAVIGMTGLLLDTDLNPEQRDFVETVRASGDALLTIINDILDFSKIESGKLDLEQQPFNLRSCIEDSLDLLASRAAEKGVELAYLIEPSTPEMIIGDVTRVRQILVNLLSNAVKFTEKGEVVVSVSASAIPPQQAGGIGTDSLILKDQETTNGHLHKDLNPDSSAGNPLCQIQFTVSDTGIGIPPERMNRLFKSFSQVDSSTTREYGGTGLGLAISKRLSELMGGRMWVVSGEGVGGDPDPAFQWPIASSVQEQSSPMPDPEQSIFTLTDAKSDQADTPPTGSTFYFTVMATPAVNPLPVDLNGTQPSLAGKRVLIVDDNATNRQILTRQALFWGMKPKAASSAREALDWLQNSEMFDIAILDMQMPQMDGITLASYIRGIVKNREFPLVMLTSIGRQEVDLPDKVPFAAFLNKPIKQSYLYNVLAGIFGGVPILSRPVHLNAVAIDPQMAQQKPLRILLAEDHLVNQKVALQILHRLGYRADVAGNGIEVLQALDRQHYDVVLMDVHMPEMDGLAATRQICQDALDGRLSHRPRIIAMTANAMQGDRELCLDAGMDDYISKPIRMPELVEALALTPVDSDHSPHHLTPTLSRADSEGPGSKLFGSDSEHPPGSPSMAIADPVLNPAMLESLREIEALEEVIEIYLEESPKLIDLLTVAIAQDDSFELQEAAHSLKSTSAAVGAMSLADLSQQLESIGRSHHNTNTPPPPEVTEIFSDLILEYQRVKTALNWELEQGESS

Crispr_ID: NC_019693_41

• CRISPR_ID: NC_019693_41
• CRISPR_location: 4466790-4467031
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_019693_41

Consensus_repeat	Method
TAAAGCTTTCCCCCGACGATACCAGGCCCAATAGTCAT	PILER-CR

spacers of NC_019693_41

>41.1|4466828|64|NC_019693|PILER-CR
CCCGGCGTTCTTTGAGGGCCTGGTCAAAGCTGGCGACTGCCTCCTCAACCTGTCCGAGTTCCCC
>41.2|4466930|64|NC_019693|PILER-CR
GTGATCGCAATTCTAGGGCTTTATCGTAATTGGCAATGGCCTCTTCATGACAGTTTGTATGTCT

CRISPR arrays and Neighbor proteins around NC_019693_41

CRISPR arrays

The CRISPR arrays of NC_019693_41

>merge|NC_019693|41|4466790-4467031|PILER-CR
TAAAACTTCCCCGCGACGATACCAGGCCCAATAGTCATCCCGGCGTTCTTTGAGGGCCTGGTCAAAGCTGGCGACTGCCTCCTCAACCTGTCCGAGTTCCCCTAACGCTTTACCCCGTTGATACCAGGCCCAATAGTCCCGTGATCGCAATTCTAGGGCTTTATCGTAATTGGCAATGGCCTCTTCATGACAGTTTGTATGTCTTAAGGCATTCCCCCGACGATACCAGGCCCAATAATCAT

>NC_019693|41|5|4466790-4467031|PILER-CR
TAAAACTTCCCCGCGACGATACCAGGCCCAATAGTCAT	CCCGGCGTTCTTTGAGGGCCTGGTCAAAGCTGGCGACTGCCTCCTCAACCTGTCCGAGTTCCCC
TAACGCTTTACCCCGTTGATACCAGGCCCAATAGTCCC	GTGATCGCAATTCTAGGGCTTTATCGTAATTGGCAATGGCCTCTTCATGACAGTTTGTATGTCT
TAAGGCATTCCCCCGACGATACCAGGCCCAATAATCAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_044197363.1|4480307_4481051_-|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl|CDD|376667
NC_019693.1|WP_015149744.1|4459035_4460349_+|serine-protease-inhibitor	unknown	unknown	gnl|CDD|381054
NC_019693.1|WP_156823879.1|4467753_4468947_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|274350
NC_019693.1|WP_015149746.1|4461993_4462605_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149748.1|4463559_4464204_+|ATP-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234971
NC_019693.1|WP_015149742.1|4457271_4457880_+|thiol:disulfide-oxidoreductase	unknown	unknown	gnl|CDD|183298
NC_019693.1|WP_015149753.1|4470802_4471123_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149741.1|4455756_4456818_+|NAD-dependent-epimerase	unknown	unknown	gnl|CDD|187563
NC_019693.1|WP_015149755.1|4472869_4474270_-|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NC_019693.1|WP_015149752.1|4469069_4470479_+|aspartate-ammonia-lyase	unknown	unknown	gnl|CDD|237031
NC_019693.1|WP_083896871.1|4475631_4476699_-|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	unknown	unknown	gnl|CDD|273015
NC_019693.1|WP_015149761.1|4481704_4482091_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149743.1|4458084_4458936_+|metallophosphoesterase	unknown	unknown	gnl|CDD|277331
NC_019693.1|WP_015149749.1|4464289_4466164_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NC_019693.1|WP_015149759.1|4479125_4479863_-|glutathione-peroxidase	unknown	unknown	gnl|CDD|223750
NC_019693.1|WP_015149745.1|4460657_4461941_+|serine-protease-inhibitor	unknown	unknown	gnl|CDD|381054
NC_019693.1|WP_015149740.1|4454466_4455750_+|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl|CDD|185104
NC_019693.1|WP_015149758.1|4476931_4478959_+|mechanosensitive-ion-channel	unknown	unknown	gnl|CDD|366370
NC_019693.1|WP_015149754.1|4471259_4472219_+|DUF362-domain-containing-protein	unknown	unknown	gnl|CDD|224917
NC_019693.1|WP_015149747.1|4462722_4463436_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_044197363.1|4480307_4481051_-|sulfite-exporter-TauE/SafE-family-protein	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.6983e-16
NC_019693.1|WP_015149744.1|4459035_4460349_+|serine-protease-inhibitor	gnl|CDD|381054	cd19588, serpin_miropin-like, serpin miropin and similar proteins. Miropin, the serpin from Tannerella forsythia, is thought to contribute to the virulence of periodontal pathogens by inhibiting neutrophil serine proteases. Miropin broadly inhibits serine endopeptidases (SEPs) including trypsin, neutrophil elastase, pancreatic elastase, subtilisin, and cathepsin G and cysteine endopeptidases (CEPs) including papain, calpain-like peptidase Tpr, and gingipain K through various reactive-site bonds. This is achieved by offering several target bonds of the RCL for cleavage within a bait region, instead of a single RSB as found in canonical serpins. In addition, promiscuous inhibition is facilitated by the capacity to insert strands deviating from the canonical length into the central sheet A, while keeping the prey peptidase bound and inactivated. The structural adaptation of miropin to provide a relaxed inhibitory specificity, which allows for formation of inhibitory complexes using different sites, is unique among serpins. SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate blood coagulation cascades. Non-inhibitory serpins perform many diverse functions such as chaperoning proteins or transporting hormones. Serpins are of medical interest because mutants have been associated with blood clotting disorders, emphysema, cirrhosis, and dementia. A classification based on evolutionary relatedness has resulted in the assignment of serpins to 16 clades designated A-P along with some orphans.	1.58475e-172
NC_019693.1|WP_156823879.1|4467753_4468947_-|tetratricopeptide-repeat-protein	gnl|CDD|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	1.15945e-20
NC_019693.1|WP_015149748.1|4463559_4464204_+|ATP-phosphoribosyltransferase	gnl|CDD|234971	PRK01686, hisG, ATP phosphoribosyltransferase catalytic subunit; Reviewed.	8.53633e-113
NC_019693.1|WP_015149742.1|4457271_4457880_+|thiol:disulfide-oxidoreductase	gnl|CDD|183298	PRK11752, PRK11752, putative S-transferase; Provisional.	1.60569e-82
NC_019693.1|WP_015149741.1|4455756_4456818_+|NAD-dependent-epimerase	gnl|CDD|187563	cd05253, UDP_GE_SDE_e, UDP glucuronic acid epimerase, extended (e) SDRs. This subgroup contains UDP-D-glucuronic acid 4-epimerase, an extended SDR, which catalyzes the conversion of UDP-alpha-D-glucuronic acid to UDP-alpha-D-galacturonic acid. This group has the SDR's canonical catalytic tetrad and the TGxxGxxG NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	0
NC_019693.1|WP_015149755.1|4472869_4474270_-|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	1.47382e-63
NC_019693.1|WP_015149752.1|4469069_4470479_+|aspartate-ammonia-lyase	gnl|CDD|237031	PRK12273, aspA, aspartate ammonia-lyase; Provisional.	0
NC_019693.1|WP_083896871.1|4475631_4476699_-|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	gnl|CDD|273015	TIGR00326, eubact_ribD, riboflavin biosynthesis protein RibD. This model describes the ribD protein as found in Escherichia coli. The N-terminal domain includes the conserved zinc-binding site region captured in the model dCMP_cyt_deam and shared by proteins such as cytosine deaminase, mammalian apolipoprotein B mRNA editing protein, blasticidin-S deaminase, and Bacillus subtilis competence protein comEB. The C-terminal domain is homologous to the full length of yeast HTP reductase, a protein required for riboflavin biosynthesis. A number of archaeal proteins believed related to riboflavin biosynthesis contain only this C-terminal domain and are not found as full-length matches to this model. [Biosynthesis of cofactors, prosthetic groups, and carriers, Riboflavin, FMN, and FAD].	5.32479e-132
NC_019693.1|WP_015149743.1|4458084_4458936_+|metallophosphoesterase	gnl|CDD|277331	cd07385, MPP_YkuE_C, Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain. YkuE is an uncharacterized Bacillus subtilis protein with a C-terminal metallophosphatase domain and an N-terminal twin-arginine (RR) motif. An RR-signal peptide derived from the Bacillus subtilis YkuE protein can direct Tat-dependent secretion of agarase in Streptomyces lividans. This is an indication that YkuE is transported by the Bacillus subtilis Tat (Twin-arginine translocation) pathway machinery. YkuE belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	9.45242e-55
NC_019693.1|WP_015149749.1|4464289_4466164_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	5.38059e-171
NC_019693.1|WP_015149759.1|4479125_4479863_-|glutathione-peroxidase	gnl|CDD|223750	COG0678, AHP1, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	2.64242e-92
NC_019693.1|WP_015149745.1|4460657_4461941_+|serine-protease-inhibitor	gnl|CDD|381054	cd19588, serpin_miropin-like, serpin miropin and similar proteins. Miropin, the serpin from Tannerella forsythia, is thought to contribute to the virulence of periodontal pathogens by inhibiting neutrophil serine proteases. Miropin broadly inhibits serine endopeptidases (SEPs) including trypsin, neutrophil elastase, pancreatic elastase, subtilisin, and cathepsin G and cysteine endopeptidases (CEPs) including papain, calpain-like peptidase Tpr, and gingipain K through various reactive-site bonds. This is achieved by offering several target bonds of the RCL for cleavage within a bait region, instead of a single RSB as found in canonical serpins. In addition, promiscuous inhibition is facilitated by the capacity to insert strands deviating from the canonical length into the central sheet A, while keeping the prey peptidase bound and inactivated. The structural adaptation of miropin to provide a relaxed inhibitory specificity, which allows for formation of inhibitory complexes using different sites, is unique among serpins. SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate blood coagulation cascades. Non-inhibitory serpins perform many diverse functions such as chaperoning proteins or transporting hormones. Serpins are of medical interest because mutants have been associated with blood clotting disorders, emphysema, cirrhosis, and dementia. A classification based on evolutionary relatedness has resulted in the assignment of serpins to 16 clades designated A-P along with some orphans.	0
NC_019693.1|WP_015149740.1|4454466_4455750_+|nucleotide-sugar-dehydrogenase	gnl|CDD|185104	PRK15182, PRK15182, Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB.	5.97556e-149
NC_019693.1|WP_015149758.1|4476931_4478959_+|mechanosensitive-ion-channel	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	9.82281e-56
NC_019693.1|WP_015149754.1|4471259_4472219_+|DUF362-domain-containing-protein	gnl|CDD|224917	COG2006, COG2006, Uncharacterized conserved protein [Function unknown].	1.93136e-124
NC_019693.1|WP_015149747.1|4462722_4463436_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.31334e-84

Protein sequences

>NC_019693.1|WP_015149749.1|4464289_4466164_+|ABC-transporter-ATP-binding-protein
MTRLSPPPTPEEGRSRRRENDWRLFLRLVPYARRSGRLLGISLILLVPLAFAGAVQPIIIGQAISLIRGEPINLQFLATLTLPQGLNLLSGLLLLTITLRFALQAIQSYFVQEVGQKITADIRNDLFDHVTSLAVRFFDRTPVGRLITRLTSDVEALGEVFSTGAIGVITDLFSIAIVLIIMFYRQWQLALLLLLMLIPIASLIIYFQQQYRQENYKAREELSSLNSKLQENIVGVGVVQIFRREAFNAEIFRVNNQRYIKAVDKTIFYDSAVSATLEWIAFVAIAGVLWLGGQLVLGDSMTVGRLAEFILFSQRLFDPLRQFADKFTAIQAGFTAIERISDIFNETIEIRDPDVKERAVGAPWQGAAPENNSVAIADSNPHAGEIRFQNVSFAYKNDEYVLKNLDFTIKPGEKVALVGPTGAGKSSIVRLLCRLYEASQGQILVDGVNVRDMRQAELRQHIGVILQDGFLFAGDVKSNISLGETYTLAEIQSAAERTNVASFIEDLPQGYNTQLRERGTNLSGGQKQLLAFARAAIRNPKILVLDEATASLDVGTESLIQDALDHLLQDRTAIIIAHRLSTIKNVDRILVLKQGQLVEQGSHEELLQQGGLYAGLYQLQMLGK
>NC_019693.1|WP_015149748.1|4463559_4464204_+|ATP-phosphoribosyltransferase
MLTVALPKGSLLTDSIRLLQSVGLDFSAFLDSSNRQLQILDPTGTARALLVRTHDVPVYVEYGQAQLGVAGYDVLREKQPRVAQVLDLGFGHCRLSVAVKESSPYRRSLDLPAHGRVASKFVHCAREYFQRLDLPVEIVPLSGSVELGPITGMSEAIVDLVSTGRTLKENGLIEMEVLFQSSARLIAHPISYRLNTDGICDRIAAIREMTTTAV
>NC_019693.1|WP_015149747.1|4462722_4463436_-|response-regulator-transcription-factor
MRILLVDDEVQLTEPLTRVLTREGYQVEVASDGATGAELARQGGYDLLILDWMLPHQSGLAICQEIRRQGDVTPVLFLTAKDTLDDRVQGLDAGADDYLVKPFELLELLARVRAQLRRSITQKTPDPETHLHRDDLELDRENQLAYRGGRTIELSEKESTLLAYFMRHSGQLLTHSEIYQHLWPTGEKPSSNVLAAQIRLLRRKIEAPGEVPLIHTVYGKGYRFGSGGESSPSSGPD
>NC_019693.1|WP_015149746.1|4461993_4462605_-|hypothetical-protein
MYLDYLWKTLTQSGNNRSRFKSLGLPLLLAIVTLTTLSCTTSPQSSQSPQSPQSPQSPVVNPNSPPIQDDRGSDTPDEMPPVASSVLPQTNAQGDYTGKSNHINWRVVDPDPNGLNCRMGDRTIDQVWTPSAGALDIGSWPVTGTLPPDSTFQAALSPGGFVLTFDANNQPWMFVESSNGPEQTSNCFIRANTNYIEPLTNSR
>NC_019693.1|WP_015149745.1|4460657_4461941_+|serine-protease-inhibitor
MNRLFFDFGKPLGAIATAILAWTLVTSVPVQSRSLSHSSTSPNQTTSLTNLDETTSIYTPFAFKLFSTIQQQQSQENIFISPASITNALAMTYNGADGTTQMAIAEALEIQGMSLEDFNQANAAIKTLLSEEYEAVEINIANSLWLNQTASFLPNFLQRVTEFYQAQLNRLDFTSPTATDEINAWVREQTNDKIPKIIDEINANDILYLMNAIYFKGTWTEAFSEELTEEKPFRRMDGTTQPHPFMLQIGNYLYLENSEVQAISLPYGNGQFSLYVLLPRETANLDEFYQGLNAEQWDDWIQAMRLQDGVIQLPRFELEYSIALNDTLEQIGMGIAFSPNQADFSKMTTENVHISAVQHKTFLEVNEEGTEAAAVTSVGVTRVSLDERPEPELFSMIVDRPFFMAIRDNRTQTILFMGSIVDPPPSN
>NC_019693.1|WP_015149744.1|4459035_4460349_+|serine-protease-inhibitor
MKKDCMDAVRPIALLGAVAIATLGWMARLEGSEPLSAQIPAINMSGHRAFGPGWITLNGTLENTVETKPIIAANTRFGIKLFSHIYQQEKAKNIFISPLSLTLALQMLNGGATGETHEAIASVLETPGMEQQQIDLTLSALHTHLHEMDSEVELTIANSFWMKEGGSFNPNFIQRTETSYQALTREIDFSSPATAAPVINGWIAEETHQRIDHILEPNDFDSGTIAMLINAIYFKSAWLSPFSESDTREHPFALADGQMKAHPLMFQTQEFAYYENALFQAISLPYGNTAEVNLYIFLPNPEVGLDLFLEHLNAENWNLWLKEYWENKPIRLGLPRFKIEYDIELKDILTAMNMGIAFSSEADFSSITSEPFWISKIKHKTFLEVNEEGTEASAVTGILGTRSGPVDMIIDRPFFFAIRDDNTGTLLFMGTLVNPLE
>NC_019693.1|WP_015149743.1|4458084_4458936_+|metallophosphoesterase
MHGFLTGSLKIERLNVAIADLPTHLRGTKLVQLSDFHYEKEGLSDKLLAEAIAVSNHADPDLVLLTGDYVTTNPDCVYALALQLKHLQSRRGIYGILGNHDIKLPHSKSTIIAAFEKIGIPILWNEVVYPLGSGLAVVGMAEVQSGQFNSRAVFPGIEASIPRIVLSHNPDTATYLQKLRVDLQLSGHTHGGQIILPKIGPVPAYLKYLRERIPKRWRQWIPYLSKDCYKIIDRWEWSQGLHQVGNNQLYVSRGLGTYFPGRLFCPPEVTIITLQGHQDKQRG
>NC_019693.1|WP_015149742.1|4457271_4457880_+|thiol:disulfide-oxidoreductase
MIDLYTFPTPNGRKVSILLEELEISYNVHKVDITKGEQFSPDFVEINPNSKIPAIIDNESEMTIFESGAILMYLAEKTGKLLPRETKSRYQVMEWLMFQMASVGPMFGQFNHFNRFAPEKVPYAIARYEQETLRLYGVLDRQLADRLYIAGEDYSIADIALFPWVASYEFMGLTLEKHPHLKRWVELLQQRPAVQRGMAVPA
>NC_019693.1|WP_015149741.1|4455756_4456818_+|NAD-dependent-epimerase
MKPILVTGAAGFIGFHLCQRLLGRGEAILGIDNLNDYYDVNLKRSRLALLQAHPQFEFCQLDLSDRQGMEKLFADYQPDRVINLAAQAGVRYSLTHPHAYVESNLIGFTNILEGCRHNHVKHLVFASSSSVYGANTKMPFSVRDNVDAPISLYAATKKANELMAHTYSYLYGLPTTGLRFFTVYGPWGRPDMALFLFTEAILAGKPIPVFNYGKMKRDFTYVDDIITGVVRVLDRIPKNNPESTETHSPNPSLTVPYKVYNIGNNQPVELLRFIEILEDCLGKKAEKEFLPMQPGDVPATYADIEELEQDVGFRPSIPLEVGIPRFVSWYQSYYRPFSGNPLPSFADCLPTLE
>NC_019693.1|WP_015149740.1|4454466_4455750_+|nucleotide-sugar-dehydrogenase
MSEKIAIIGLGYVGLPLAIALAKQFPDTVGFDINPEKIHALTQGIDATGEVCLNNLKSTSLQFTSDPNHLKSSNFFIVAVPTPIDSNHHPDLTPLIRASELVGRVLQPGSVVVYESTVYPGVTEETCGTILAQESGLRPGIDFKLGYSPERINPGDPEHRLETIIKVVAGEDAETLERVAQVYESIIKAGIYRAPSIKVAESAKVIENIQRDLNIALMNELALIFDRLNISTHEVLAAAGTKWNFLPFKPGLVGGHCIGVDPYYLTAKAKQVGYRPEVILAGRRINDNMGRYLGQRLIKLLTNHENIPIKQVRVGILGMTFKENVPDTRNTRVPDIVAELEQFGIRPLVHDPIANPEEVHQVYDISLSPWSEFFALDALILAVPHRQYLECSPDELIECLNPEGIFMDIKSVLGPSLFPSKIVYWSL
>NC_019693.1|WP_156823879.1|4467753_4468947_-|tetratricopeptide-repeat-protein
MSQTMSRAISIYERTLECRPDSYWEWYQQANAMRDAGHYHDALSCYDKAVEYRPEDYWAWYQIGNVLDELGRYEEAVASYDRALKARPGDYWAWYERGSAFRQLREYDEAVASYDRALEARPGDYWAWYERAITLARASRYEEAVASYDRALEVRPTDYWAWYRRGIALEMMQEYEKALASYDFALEMKPTAEMAWYRQGKMLDLLGETEAAIASYDRALEIDPEDDLVWYDRGIALDDLGRPAEALQCYERAISIYSDNFWPWYQLGNAHSQLGNYEEAVASFDRALECEPNWTRWGEDYERLSGWVWHDLGIALGELCRYDEAVMSFQKALTIEPEDGAIWYDLARYLIRQGDGLGAVASLEQAIHWGGDSYLEKLATDREFDGLRGDRTFQGLM
>NC_019693.1|WP_015149752.1|4469069_4470479_+|aspartate-ammonia-lyase
MSEQSELDYRIERDSMGERQIPAAAYYGIQTLRATENFPISGLKPLPTYLDACLLIKKATALANGELGCIPPELSQAIADAADEILNGALRDQFVVDVYQAGAGTSHHMNVNEVLANRALELLGDVKGNYQRISPNDTVNYGQSTNDVIPTAIRIGGLLALQHSLYPALNKAIAALEAKAVEFQDIVKSGRTHLQDAVPVRLGESFRAWAYILTEHRTRIETAGKELTVLGIGGSAAGTGLNTHPKYRAQVVKILSELINIPLTPTPHLMAAMQSMAPFVSVSGSLRNLATDCLKISHDLRLMDSGPKTGLKEIQLPPVQPGSSIMPGKYNPVMAEMTSMVCFQVMGYDSAIALAAQGGQLELNVMMPLIAYNLIHSIEILGHAIGALSEFCLQGITCDRSRCEQYAEGSLALVTALNPHIGYLNAAAVAKESLETGKSLRQIVLERGLMTSEQLAEVLDLQKMSALPN
>NC_019693.1|WP_015149753.1|4470802_4471123_+|hypothetical-protein
MARGSFATMQAQSSTEVTFYYENGHTDSFKVPVPGPQFQQQLPQLLAQPWIIFHLMDNTVIVSTAKVIKVEINPPVPELQGPGVINNGERVTTMQRGATGRLPQSG
>NC_019693.1|WP_015149754.1|4471259_4472219_+|DUF362-domain-containing-protein
MTIVSLIRANSYEQAVLRASIETVLAPLGGMAAIVKPGSRVLLKPNLLTGSRPTKECVTRPEIVSCVAEMVMEVGGKPFLGDSPAFGSARGVAFANGYQEIVEQLNLPIVEFHGKRYPTNATEFNHLRLSKEAMEADVVINLPKVKSHVQLTMTMGVKNLFGCVPGKMKAWWHLEAGKDVNRFGEMLVETARAISPNLTIVDGIIGHEGNGPSGGEPRLLGLLAASENVFACDRALLEVLNVSPELVPTAAASLRLGVCPELAEIQFPLLKPVDLKVDDWKLPEALVPLDFGMPRVLQSTFRHLYIRFIKEPIKLYGNR
>NC_019693.1|WP_015149755.1|4472869_4474270_-|CHAT-domain-containing-protein
MNVFANEGQPDIYRGFERILVIQRRTESALEVAEQGRAKAVEHLLASRLGPEGKCHGSVEPPSLYKIKQIAKAQNSTLVYYSLIYDYQQFYEMSRLQIGLNTLYAYATELFIWVISPAGKVSFRQVDLQSLWSEDNTSLAGLVRSVRELINVGYSDRERLLCRQQLQFLYQILLEPIADLLPQDPQKRVTIIPQDFLFLVPFAALIDSNGQYPIEKHTLLTAPSIQALEVTHRQRKPIVERELALQTVGGNSSLDCSPPLESPQECLVVGNPTMPSICLEFGEPPVQLLQIPGTQLEAEAIAQVLQTQAITGDRATKSAILEKMRSADIIHLATHAFLDDIEGLQSAIALAPSPNNHGLLNINDILHLNLQAELVVLSGCDTGRGRIWGDGVVELSQAFITAGVPSLLMSLWLPPSSSNLDFMKEFYHQFRQTCDKAQSLRTAMLTTMEQYPNPREWAAFTLIGEA
>NC_019693.1|WP_083896871.1|4475631_4476699_-|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD
MMRRCIELAQLALGKTAPNPLVGSVIVKEGQIISEGFHPGAGHPHAEVFALQGAGEQAAGATVYVNLEPCNHYGRTPPCSEALIAARVAKVVVGMVDADPRVSGGGIQRLRSAGIEVVVGVEEEACRQLNEAFLHRVIYHRPFGILKYAMTLDGKIATTTGHSTWITSTEARHEVHTLRAVCDAVIIGGNTVRQDNPQLTSHHTGTQNPLRVVMTRTLDLPKAANLWEVSEAGTLVLTQKGANPDMQQWLLNKGVEVIELDPLTPAIAMEYLYQREFLSVLWECGGLLAARAIADGAVQKILAFIAPKIVGGQAAPSPVGNLGLTQMGDALTLDRVKWRTIGTDCLVEGYLKLKE
>NC_019693.1|WP_015149758.1|4476931_4478959_+|mechanosensitive-ion-channel
MDIQKSQDIKPARTGRLPLVGGKIAKRTGQWMAIAALQVLSLQVSPVPAAIGQIPPQQSNPEASTDESETTDTAAESPPQSSTTAALLSLSPNNWLSEDWFSQYLNRPVRLDGRTLFPVAPIELSEGSRVEAIERQLQQLLEAVETELQQNRQTQNPDGTYSSDEINTFINQNLQIYNNPLGGLPVIYARWGRGETQQIRLLTVTQVDADRLGMPLEMVADRWQQQIRQGLLRALLERQPDYLEKQVVWSVSIGLAIVLSSLLLFYYQKQFKRKRDQILATSYLTPLERTPVPLREVEHSEDSVPVAESESIEMQQQAESMRELQYKMNKQQQLNVNDIQRRLAQFGQVVIWGGGTYSILGLFPMSRGIQVLILSLLPVPLRLFGVVLSTYVGVRLSAIAIDRFFSVLQEGKLVDLNASRRLALRFSTFSGVFKSLTAAGCVSIGILMTLSVIGLDIAPILAGAGIIGLGISLASQSLIKDTINGFLILFEDQYAIGDVILVDDVGGLVENMNLRITQLRNGEGQLITIPNSAISIVRNLSKEWARVDLTIIVAYQNNVDRVLQVLQELSLEIYSEPEWQEKMIDAPEVLGIDQIDYSGILIRIWIKTKPLQHWSVAREFRRRMKTRLDQHGIAIGVPQQSVVFQSSLELLKQARNSNGDRSPKILMGNSDQASS
>NC_019693.1|WP_015149759.1|4479125_4479863_-|glutathione-peroxidase
MLQNREGQTVPNVTLQTRQNADWATISTDDLFAGKTVIVFSLPGAFTPTCSSTHVPGYNELAPTFKSNGVDEIICVSVNDPFVMNEWKKEQKADNITFLPDGNGEFTEKMGMLVNKEDLGFGKRSWRYSMLVKDKTIEKMFIEPEVEGDPFEVSDAETMLKYINPEAKKPECVSLLTKEGCPYCARAKAALKEHGFEYEEIVLKDDITTRSLRAISGATTVPQVYINGKHIGGSDDLIQYLNQQR
>NC_019693.1|WP_044197363.1|4480307_4481051_-|sulfite-exporter-TauE/SafE-family-protein
MLLVWLTLASFLSWFTSTLAAAGSPLLLIPLVSLLLGSSAVAPVITMGMLLGNSQRIFLFWSDINWKITLWYLPGAIVGAILGAYLFTQMNIEWLQLLIGLFLILSVVGFWVKQQESSFPIATWYFLPAGFLYSFISGLIGSSGPLLNPLYLKYGLVKEEMIATKAANVVVIHIVKIAIYLAFGAMTPQYLGYGLAIGLAAAPGNLLGRYVLRSMSNQQFRQLALATMAITGILMLWQQRELLQFIH
>NC_019693.1|WP_015149761.1|4481704_4482091_-|hypothetical-protein
MLYKPSFGDRQLAESFYQALFNRFYDSVDRQTQELLRECQFGLAPSPTGVKTFFILAPDLERAQNLIEQIHGIITGVMAIMVGVHQTAICIAPPDGGDGPRQQPGQLNPRYMMAKLFPHPPQDDDEQS

Crispr_ID: NC_019693_42

• CRISPR_ID: NC_019693_42
• CRISPR_location: 4546244-4546359
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_42

Consensus_repeat	Method
AGAAACCGGGTTTTTTGAACAAATTTCTGCGAATTAC	CRISPRCasFinder

spacers of NC_019693_42

>42.1|4546281|42|NC_019693|CRISPRCasFinder
TGAGAAATCTAGGCAAAAACCCGGTTTCTAACCCCCAGGACC

CRISPR arrays and Neighbor proteins around NC_019693_42

CRISPR arrays

The CRISPR arrays of NC_019693_42

>merge|NC_019693|42|4546244-4546359|CRISPRCasFinder
AGAAACCGGGTTTTTTGAACAAATTTCTGCGAATTACTGAGAAATCTAGGCAAAAACCCGGTTTCTAACCCCCAGGACCAGAAACCGGGTTTTTTGAACAAATTTCTGCTAATTAC

>NC_019693|42|41|4546244-4546359|CRISPRCasFinder
AGAAACCGGGTTTTTTGAACAAATTTCTGCGAATTAC	TGAGAAATCTAGGCAAAAACCCGGTTTCTAACCCCCAGGACC
AGAAACCGGGTTTTTTGAACAAATTTCTGCTAATTAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015149803.1|4549027_4550128_+|family-3-adenylate-cyclase	unknown	unknown	gnl|CDD|143636
NC_019693.1|WP_015149799.1|4545883_4546216_+|hypothetical-protein	unknown	unknown	gnl|CDD|274783
NC_019693.1|WP_052315754.1|4538347_4541815_+|hypothetical-protein	unknown	unknown	gnl|CDD|225483
NC_019693.1|WP_015149802.1|4547843_4548710_-|shikimate-dehydrogenase	unknown	unknown	gnl|CDD|234703
NC_019693.1|WP_044195382.1|4529317_4530568_+|beta-ketoacyl-ACP-synthase-II	unknown	unknown	gnl|CDD|235987
NC_019693.1|WP_156823880.1|4550152_4550299_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149791.1|4533549_4533867_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149807.1|4554170_4555733_+|sodium:proton-antiporter	unknown	unknown	gnl|CDD|223104
NC_019693.1|WP_015149792.1|4534875_4537296_+|sucrose-synthase	unknown	unknown	gnl|CDD|274149
NC_019693.1|WP_015149795.1|4542641_4542842_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823881.1|4556237_4556414_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149804.1|4550919_4551834_+|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	gnl|CDD|238871
NC_019693.1|WP_015149794.1|4541977_4542541_+|peptide-deformylase	unknown	unknown	gnl|CDD|234668
NC_019693.1|WP_015149797.1|4545017_4545668_+|uracil-phosphoribosyltransferase	unknown	unknown	gnl|CDD|215297
NC_019693.1|WP_015149808.1|4556545_4557727_-|histidine-kinase	unknown	unknown	gnl|CDD|236462
NC_019693.1|WP_015149800.1|4546576_4546858_+|YggT-family-protein	unknown	unknown	gnl|CDD|376765
NC_019693.1|WP_015149805.1|4552273_4553668_-|glycogen-debranching-protein	unknown	unknown	gnl|CDD|372373
NC_019693.1|WP_015149789.1|4530822_4532853_+|transketolase	unknown	unknown	gnl|CDD|215424
NC_019693.1|WP_015149796.1|4542964_4544491_-|carotene-isomerase	unknown	unknown	gnl|CDD|131777
NC_019693.1|WP_083896875.1|4546988_4547429_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015149799.1|4545883_4546216_+|hypothetical-protein	gnl|CDD|274783	TIGR03789, pdsO, proteobacterial sortase system peptidoglycan-associated protein. A newly defined histidine kinase (TIGR03785) and response regulator (TIGR03787) gene pair occurs exclusively in Proteobacteria, mostly of marine origin, nearly all of which contain a subfamily 6 sortase (TIGR03784) and its single dedicated target protein (TIGR03788) adjacent to to the sortase. This protein family shows up in only in those species with the histidine kinase/response regulator gene pair, and often adjacent to that pair. It belongs to the pfam00691 domain family, which is the peptidoglycan-associated region of flagellar motor protein MotB, OmpA (whose N-terminal region forms an outer membrane beta barrel), and peptidoglycan-associated lipoprotein Pal. Its function is unknown. We assign the gene symbol pdsO, for Proteobacterial Dedicated Sortase system OmpA family protein. [Protein fate, Protein and peptide secretion and trafficking].	0.000401381
NC_019693.1|WP_052315754.1|4538347_4541815_+|hypothetical-protein	gnl|CDD|225483	COG2931, COG2931, RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism].	3.01525e-35
NC_019693.1|WP_044195382.1|4529317_4530568_+|beta-ketoacyl-ACP-synthase-II	gnl|CDD|235987	PRK07314, PRK07314, beta-ketoacyl-ACP synthase II.	0
NC_019693.1|WP_015149803.1|4549027_4550128_+|family-3-adenylate-cyclase	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	4.34296e-49
NC_019693.1|WP_015149792.1|4534875_4537296_+|sucrose-synthase	gnl|CDD|274149	TIGR02470, Sucrose_synthase_1, sucrose synthase. This model represents sucrose synthase, an enzyme that, despite its name, generally uses rather produces sucrose. Sucrose plus UDP (or ADP) becomes D-fructose plus UDP-glucose (or ADP-glucose), which is then available for cell wall (or starch) biosynthesis. The enzyme is homologous to sucrose phosphate synthase, which catalyzes the penultimate step in sucrose synthesis. Sucrose synthase is found, so far, exclusively in plants and cyanobacteria. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NC_019693.1|WP_015149807.1|4554170_4555733_+|sodium:proton-antiporter	gnl|CDD|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	9.05509e-83
NC_019693.1|WP_015149802.1|4547843_4548710_-|shikimate-dehydrogenase	gnl|CDD|234703	PRK00258, aroE, shikimate 5-dehydrogenase; Reviewed.	3.29795e-120
NC_019693.1|WP_015149804.1|4550919_4551834_+|PEP-CTERM-sorting-domain-containing-protein	gnl|CDD|238871	cd01833, XynB_like, SGNH_hydrolase subfamily, similar to Ruminococcus flavefaciens XynB. Most likely a secreted hydrolase with xylanase activity. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	2.43998e-31
NC_019693.1|WP_015149794.1|4541977_4542541_+|peptide-deformylase	gnl|CDD|234668	PRK00150, def, peptide deformylase; Reviewed.	7.87026e-76
NC_019693.1|WP_015149797.1|4545017_4545668_+|uracil-phosphoribosyltransferase	gnl|CDD|215297	PLN02541, PLN02541, uracil phosphoribosyltransferase.	8.26834e-104
NC_019693.1|WP_015149808.1|4556545_4557727_-|histidine-kinase	gnl|CDD|236462	PRK09303, PRK09303, histidine kinase.	0
NC_019693.1|WP_015149800.1|4546576_4546858_+|YggT-family-protein	gnl|CDD|376765	pfam02325, YGGT, YGGT family. This family consists of a repeat found in conserved hypothetical integral membrane proteins. The function of this region and the proteins which possess it is unknown.	9.71875e-17
NC_019693.1|WP_015149805.1|4552273_4553668_-|glycogen-debranching-protein	gnl|CDD|372373	pfam12899, Glyco_hydro_100, Alkaline and neutral invertase. This is a family of bacterial and plant alkaline and neutral invertases, EC:3.2.1.26, previously known as Invertase_neut pfam04853.	0
NC_019693.1|WP_015149789.1|4530822_4532853_+|transketolase	gnl|CDD|215424	PLN02790, PLN02790, transketolase.	0
NC_019693.1|WP_015149796.1|4542964_4544491_-|carotene-isomerase	gnl|CDD|131777	TIGR02730, Carotenoid_isomerase, carotene isomerase. Members of this family, including sll0033 (crtH) of Synechocystis sp. PCC 6803, catalyze a cis-trans isomerization of carotenes to the all-trans lycopene, a reaction that can also occur non-enzymatically in light through photoisomerization. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0

Protein sequences

>NC_019693.1|WP_015149799.1|4545883_4546216_+|hypothetical-protein
MSNRDNFAGGFLLGTILGGIVGGAIGAIVGAKLAEDNKVPENGTRPEPRPRKLKKRQFAEQAGMETARRSLENKIAQLNEAIDDVRQQLSHVNGTAVEETESVSVGVEES
>NC_019693.1|WP_015149797.1|4545017_4545668_+|uracil-phosphoribosyltransferase
MTIQMRVYVPPHPLIKHWLGVARDAGTPPALFRSAITELGRWLTYEACREWLPVIETIIETPLAPCPATFVNPEVPVVVVPILRAGLALMEGVQPVLPLAAVYHLGMVRDEETLEARCYLNKLPDQIDPQTRVLICEPMLATGGTIMATMAMLTERGVDPGMIRILSVVVASPALQKLSQAYPSLNIYTACIDESLNENGYIVPGLGDAGDRAFAT
>NC_019693.1|WP_015149796.1|4542964_4544491_-|carotene-isomerase
MAVASTPTSPQTDNFDVIVIGSGIGGLVTATQLAAKGAKVLVLESYTIPGGSSGSFERNGYCFDQGASMIFGFGDQGTTNLLTRALDAVKVNLETVPDPVQIHYHLPEGLDLEVHRNYEKFLQELGSRFPHEREGIRQFYDECWKVFNCLNAMPLLSLEEPRYLMQVFFQHPLACLGLVKYLPLNAGDIARKYIKDPALLKFIDIECYCWSVVPAEMTPMINAGMVFSDRHYGGINYPKGGVGQIAKKLAEGLVNAGSTIRYQSRVDKIITEKGQAVGVKLTTGAEYRAKRIVSNATRWDTFDKLLGDRELPQKEETWRSRYRKSPSFISLHLGVEAGVLPPDTACHHIVLDQWQKMEEPEGTIFVSIPTLLDPSLAPDGYHILHTFTPSWIKDWEGMSAEEYEEKKEEAAGRIIERLEEIFPGLDAGLDYMEVGTPRSHRRFLNRVDGTYGPIPRRKLWGLLGMPFNRTSIPGLYCVGDSTFPGQGLNAVAFSGFACAHRIGVDLGL
>NC_019693.1|WP_015149795.1|4542641_4542842_+|hypothetical-protein
MFMSPKTSFFLGASCVAAIASVGSIFELSSGQPELGTLPTGIILAISVPSVVLFFLAAVRDARESP
>NC_019693.1|WP_015149794.1|4541977_4542541_+|peptide-deformylase
MTSQVLVEKKKLEHPPRDIRYLGDRDLRQAAKRVAQVDADIRQLVREMLQSMYTADGIGLAAPQVGVQKQVIVVDCDLENPATPPLVLINPVIKKFGGDECTYQEGCLSIPGVYLDVKRPEIIEVAFKDERGRPQKLTAKGIVSRCIQHEMDHLNGVLFVDRVENHLALTEELTKQGFSTKDVKSML
>NC_019693.1|WP_052315754.1|4538347_4541815_+|hypothetical-protein
MSFSIHPNYSVDIIPKMAQISEPNNPLATNLPGSNLPGLDESDPLESSRTLEEDGIFLDLSLQQIIQGQAGDDTIIGSLADDTIDGNAGNDTIYGNAGNDSLLGNEGNDTIAGGPGNDIIRGVAGNNVLYGDLTREGLSLEEGFGNDIIFGGIGDDLIFGNQGDDTLDGEGGTDTIYGGKGNDVIIGHEGNDLLSGDDGNDLIYGGLGNDNISGGLGNDTLYGEDGDDILNGNEGSDLLVGGAGNDIIYGDDLTAEVFDGGNDVIYAGEGNDIAYGGVGNDIIFGNEGNDILFGNKGNDVIYGGQGDDTAYGGQDNDQLFGDKGNDVLFGNLGNDFIDGGEGDDLLLGNEGSDLLDGGSGNDIIYGGQDNDTIRGSDGDDQLFGDKGNDVIFGGTGNNTLTGGEGSDQFVISPGLGFLQQTRNLITDFTDGEDFLLLADGITFEDLDIREEFDATGTLNTLILDRLTGTVTILQNVSASQITREDFLPPVAAPPPPPPPESVPLPDIPTPPVITPPVIPGPEPEPEPEPEESVIQFSNATYRINEDGTPEAMLVTVTRTNSSEGVVTANVVLQGNPGTATAVDDYENIFPFAIQFAEGDTTPKQVTIPIVNDTRAEETETINLQLTNLTGTAVLGSQSTAIVEIIDDDNPGELEFVLPAAGSFRVKENGTVVREIQVRRVNGSSGAVSADIALAAGSASTNPPAQPGIVGEDFTAVTVPVSFTDGETATKTITLPATAILTDGQVDGLKIVNLSLTNATGGVELNTTPAPLQIEDIDQLVVSIEVTPPGNEAFEAAQADLAPDATREGVFTIALRDANGTLVNAPAGGLTVSYRVDTTAPAQPTDPEAAVEGQDYNALLNGAPFTLGSNTVVIPEGSSTATITINPIDDALPEGNEFVKLVLNETANYNIASDKQEGEVILIDNDSPIVRISPATERIKEGENPETVLTIFREDSAGNPITSGALTVNYGRGGTATNAVDYDELTGQAVIPDGQSSVTVTVRALDDNNAEPDETVRITLAGSTDATQVYELKEGQTQSVVTIEDNETPQISVVGRAADVLADPPTGNQFQFIRFGDKAIPLTVNYTVGGTAQPGTDYTALPGTINFTAGQSSVSLPLTPIDNPNDANAKVVEIQIVDGATYDLGFAGTGNLLFLN
>NC_019693.1|WP_015149792.1|4534875_4537296_+|sucrose-synthase
MSDLIESVLKCDEKIDLRQFASELRTTGQQYFLRNDIVRAFSDYCEHHEKPSYFYQSSYLGKLILYTQEIILENESLCMIIRPKIASQEIFRILEDLTVESMTVQELLDLRDRLVNHHHPNEGDVLELDFAPFYDYSPTIRDPKNIGKGVQFLNRYLSSKLFQDPQQTLELLYEFLNLHQYNGLQLLINPRIKNRRELSQKVKQALSFVGDRPPEEPFENFRFDLQILGFEPGWGNTAGRVRETLEILDELIDSPNDAVLESFISRIPMIFRIVLVSVHGWFGQEGVLGRPDTGGQVVYVLDQARSLEKQLQEEFKLAGLDTLGVNPKVLILSRLIPNADGTRCNERLEKIHGTDNGWILRVPLREYNSNLTQNWISRFEIWPYLETYAIDAEKELLAEFQGKPDLIVGNYSDGNLVAFLLARRLKVTQCNIAHALEKSKYLFSNLYWQDLDPQYHFSLQFTADLIAMNAANFIVSSTYQEIVGTPDSVGQYESYACFTMPDLYHVVNGIELFSPKFNVVPPGVNEAVYFPYTRTEDRIPSNRERLEELLFTLDDPVQVFGKLEDPNKQILFSVARLDRIKNLTGLAECFGQSPELQERCNLILVAGKLRTEESTDTEEISEMQKLYGIIEQYNLYNKIRWLGVRLSKSDSGELYRVIGDHKGIFVQPALFEAFGLTILEAMVSGLPTFATQFGGPLEIIQDKVNGFYINPTNLEETAEKLLDFVTKHEQNPHYWDEISQRAIERVYTTYTWKIHTTRLLSLAKIYGFWNYTSKENREDMLRYLEALFYLVYKPRAQALLQQHWDR
>NC_019693.1|WP_015149791.1|4533549_4533867_-|hypothetical-protein
MKSSKLSTILSATVLSAGLAFAPSTLPASAQTTPVTPTQEVYETEQGTQGIEDDNDWGAWGLLGLLGLLGLAGLGGRNRNESPTYYADPTRDREEVAGRSSTTYR
>NC_019693.1|WP_015149789.1|4530822_4532853_+|transketolase
MAVSAPTKQSLEELCINSIRFLAIDAVEKANSGHPGLPMGAAPMAFVLWDKFMRFNPKNPKWFNRDRFVLSAGHGCMLQYALLYLTGYRGLELEDLKQFRQWESKTPGHPENFQTEGVEVTTGPLGQGIANAVGLAVAEAHLAAKFNKPDLKIVDHYTYVILGDGCNMEGISGEACSLAGHWGLGKLIAFYDDNHISIDGSTDISFTEDVSKRFESYNWHVLHVENGNTDLDAIAKAIEEAKKVTDKPTLIKVTTTIGFGSPNKANSHDVHGAALGASEVQATRDHLGWNYGPFEVPEDALGHFRKAVDRGAKYEEEWNSLWTRYTAEYSEEAAVLERMMSGKLPDGWDKALPTFKPGEKADATRNQSGACLNAIAGVLPDLIGGSADLAPSNKTLLKSSKDFQKGAYENRNVRFGVREHGMGAICNGIALHGSGLISYGATFLVFTDYMRGAIRLSALSQAGVIWVMTHDSIALGEDGPTHQPIEHIPSLRAIPDLIVLRPADGNETSGAYKVAVEKAKGIGADHPYPSLLALSRQNLPNLEGTSIEGVAKGGYTISDSEGTPDIILIGTGGELYLCAEAAEKLRGQGKKVRVVSMPSCELFDEQDEAYRESVLPKAVKKRLVVEAGSSYGWHRYFGDQGSSISVDRFGASSPGEVALERFGYTADNIAAKAAAL
>NC_019693.1|WP_044195382.1|4529317_4530568_+|beta-ketoacyl-ACP-synthase-II
MTSLERKRVVVTGLGAVTPIGNTLQDYWEGLLSGRNGIGPITLFDPSSHSCRIAGEVKGFDPHDYLEKKEAKRMDRFAQFAIAASKQAIADASFEINDLSAEQVGIVIGNGIGGMKVMEDQQTIYLNRGPDRCSPFMVPMMIANMAAGLTAIHTGAKGPNSCVVTACAAGSNAVGDAFRLIQGGYAQAMLCGGTEAAVTPLSVAGFAAARAVSTRNDDPLHACRPFDRDRDGFVMGEGAGILLLEELEHALARGAKIYAEMVGYAMTCDAYHMTSPVPGGEGATRAMLLALKDAGLSPEQVSYINAHGTSTAANDKTETNAIKNALGDHAYKIAVSSTKSMTGHLLGGSGGIEAVATVMAVAHDKVPPTINLENPDPECDLDYVPHHSRDCPVNVALSNSFGFGGHNVTLAFAKYQ
>NC_019693.1|WP_015149800.1|4546576_4546858_+|YggT-family-protein
MNPLDLIFSTLAAFCQIYFVLLIIRVLLSWFPNVNWYDPPFSIVSQLTDPYLNIFRSFIPPLGGIDISPMLAILLLQFVGQLFSSFPSAVSTF
>NC_019693.1|WP_083896875.1|4546988_4547429_-|hypothetical-protein
MKRIILPIAIAIGLFWFSPPALALTDIQIADIAYKDCGEELSEGIVASGDMSAANCFIISGTAKNTSGKPVYDADVFGVIYDANNNNIMPNRTRIGNIQSVPPGNSDFEFRISVPANLPTPFKLDKFKARGFSGRVKPLLYETNLE
>NC_019693.1|WP_015149802.1|4547843_4548710_-|shikimate-dehydrogenase
MPTITGTTQLLGVIGYPVKHSLSPVMHNAAITDMGVDFVYLPWPVAPSDLPTAIAGFAAIGVRGFSITIPHKQAIMPLLSEISPVAQAVGAVNTVWRTPTGWAGTNTDVEGFLAPLKGGDRPWHQTLAVILGCGGAARAVVAGLAQLGCAKICVVGRNLDKLQAFQTSWQDSPWPVNLSVHDWSELPQLLPQAGLLVNSTPVGMSPDVGHSPVTPDLLATLPQGAIAYDLIYTPSPTEFLRQAQAVGLLAIDGSEMLVQQGAAALQIWLDRPVPIDIMGQALRQHLRG
>NC_019693.1|WP_015149803.1|4549027_4550128_+|family-3-adenylate-cyclase
MKRLTYISKFSRPLSGDEIEAIGRISSQKNQQANVTGVLLCLDGIFFQILEGEAEKIDRIYERILADERHTDILCLKSEVEVQERMFPDWSMQTINLDENTDFLIRPIKVLLQTLTESHRILEKYTQPSIFKIISQGTNPLNIRPKAVEKIVFFSDIVSFSTFAEKLPVEEVVSVVNSYFSVCTAIITRQGGEVTKFIGDCVMAYFDGDCADQAIQASLDILMELEILRNSAPEGSPLRVLYSGIGLAKGKVIEGNIGSELKRDYTILGDAVNVAARLEALTRQLSQALVFSSEVKNSATKSWNFIWLTDSELKGKSESIDIYSIDNEMTRKSSGGLEIARNIGHYLERVGDRQPSQIFGVKSLPL
>NC_019693.1|WP_156823880.1|4550152_4550299_+|hypothetical-protein
MTQPDLDISSENIGPWQQGDSAGVTCLGWVPQILGWEFFRGDRREQTF
>NC_019693.1|WP_015149804.1|4550919_4551834_+|PEP-CTERM-sorting-domain-containing-protein
MKKMNLTLTSAGFATLLLLGATSSPVQAFSLTQSNPLKIMPLGDSNTRGHGNDPAGYRDDLWMLLNESEFNVDFVGSEIRNPPSNWDQPYAFDRNHQGHGGYAISGSPHDWAGDLMDNIDNWLNAATPDVILLMAGTNDFLHQDTTAQEKIDELGILIDKIFAWSSDVNLLVSSIAPLAPNRGLAQEVTLYNDLMPGLLGSDRYQQNNLSFVDTRHLFTLDDLHDGIHFTPQGYTTLAHAWFDGIVSASDLAQPPTDPIVVETPGSGDLVSIPEPTSVLGVLAFGLVGAGSLRKRRHVSCLSSR
>NC_019693.1|WP_015149805.1|4552273_4553668_-|glycogen-debranching-protein
MKRKEINPADAHALLENSIFYYQGEPAGTVAAHDPELDALNYDQCFIRDFVSGALIFLIEGKTDIVKNFLIHTLALQKHDKRMDCFEPGAGLMPASYKVVHEEGGDELLGDFGNHAIGRVPPVDSGFWWLFLLRAYVKKSGDMSFAHQPEFQEGIKLILELCLLSRFEMFPTLLVPDGSFMIDRRMGVYGHPLEIQALFYIAMRSARELLRSDNEDGRSYLQAIKSRLGSLRFHIREYYWLDFKRLNEIHRFESEQFGKNAVNKFNIYPGSIPHWVTLWMPDRGGYLAGNLGPGQIDFRFFSEGNLMAILGSLSSEEESQGIIQLIEKRWDDLVGRMPLKIAFPAVENLEWEIVTGSDPKNPPWSYHNGGNWPVLIWPLVAACQKMGRPDLGEKALKIAGDRLIEDEWPEYYDGKNGRLIGKEARRYQTWTISGYLLGKMLQENPESLSLMSFDEDPEIQGCPV
>NC_019693.1|WP_015149807.1|4554170_4555733_+|sodium:proton-antiporter
MSIEPTTSEALIKQSLERFLLVLTVSLSVATLPQIFSWVRQIPYTLLLVIVGLGLAFVDVRLVNLSPALILSIFLPPLLFEAAWNLQWKDLKRDLVPVSLYAILGVLISVLGIAIALNQFAAIPVATALLIGASLSATDPISVIALFRELGVEKRLSTLMEGESLFNDGVAVVAFSLLVGLALGTSQFEVRGTIAQFGAFVGIGVGIGSLIGFGISYLTQRFDLPLVEQSLTLVSAYGTYLIVEELGGSGVIGVVTVGLVLGNFGSRIGMNPRTRLIVTEFWEFLSFFVNSIVFLLIGDQIQFASLARNLDTIAITLLAMLFTRAIAIYALGALSNVLVKSDINLRQQTVLWWGGLRGSVSIALALSVPIILEAREEIIATVFGVVLFTLLVQGLTTKPLLKVLNLLGDQTVRQNYLEAIARRAALQRVLNHLKEGQDGPDIDWEFYRYQTALVEGQIKDIQNNINQMRSKEPELQDFAREQFKEELLAIEADTYAEFVRSGRLNRDLAPFLQDVLTGGD
>NC_019693.1|WP_156823881.1|4556237_4556414_+|hypothetical-protein
MNEWVVSSRANAIALARSKDVFPASIQALKPLRMCDVAIAQEEPHPNPPLAKGRGPET
>NC_019693.1|WP_015149808.1|4556545_4557727_-|histidine-kinase
MRAIPGKTMHQNHEAPLQLVLFVDRRPRSSEQIRRIRSYFQKRRTGIPFDLEIIDVSEQPYLAEQFKLVATPALIKLHPGPRQVLAGSNLVGELDKWWDRWQKSVEEYLSQQASSEAIGHYPQKPISSQLAHSAELMELSDEIFRLKQEKEELLDQLHFKDRLIAMLAHELRNPLTAASLALETLEITYKPEKSLNPEAASALRARLIYHARTQTRLIDRMISDILVAAHSTNSAEFHINPQKLNLKTLTLNILENFKDRLSAKSHTLKTDIPNDLPAVYADGERVRQVIVNLVDNAIKYTPQGGQIEVCILHRTTQKVQVSIIDNGPGIPAENQEHIFEDKFRLQRDEQKDGYGIGLGLCKRLIRANCGEIWVDSSCNKGSAFHFTLPVYRQ

Crispr_ID: NC_019693_43

• CRISPR_ID: NC_019693_43
• CRISPR_location: 4665462-4665582
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_43

Consensus_repeat	Method
AAGTTGCAACACTTATCGCAGAAACCCGGTTTCTGGTC	CRISPRCasFinder

spacers of NC_019693_43

>43.1|4665500|45|NC_019693|CRISPRCasFinder
CTTTGTAGGGGGTTAGAAACCGGGTTTCTTTCATAAATTTAGGTA

CRISPR arrays and Neighbor proteins around NC_019693_43

CRISPR arrays

The CRISPR arrays of NC_019693_43

>merge|NC_019693|43|4665462-4665582|CRISPRCasFinder
AAGTTGCAACACTTATCGCAGAAACCCGGTTTCTGGTCCTTTGTAGGGGGTTAGAAACCGGGTTTCTTTCATAAATTTAGGTAAAGTTGCAACACTTATCGCAGAAACCCGGTTTCTGGTC

>NC_019693|43|42|4665462-4665582|CRISPRCasFinder
AAGTTGCAACACTTATCGCAGAAACCCGGTTTCTGGTC	CTTTGTAGGGGGTTAGAAACCGGGTTTCTTTCATAAATTTAGGTA
AAGTTGCAACACTTATCGCAGAAACCCGGTTTCTGGTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015149865.1|4650100_4651435_-|TrkH-family-potassium-uptake-protein	unknown	unknown	gnl|CDD|273349
NC_019693.1|WP_015149876.1|4669007_4669193_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149869.1|4655852_4656830_+|homogentisate-phytyltransferase	unknown	unknown	gnl|CDD|183813
NC_019693.1|WP_044197393.1|4672702_4673308_+|dephospho-CoA-kinase	unknown	unknown	gnl|CDD|184807
NC_019693.1|WP_015149877.1|4669795_4670431_+|S-layer-homology-domain-containing-protein	unknown	unknown	gnl|CDD|306825
NC_019693.1|WP_052315756.1|4670590_4672444_-|sulfatase	unknown	unknown	gnl|CDD|293754
NC_019693.1|WP_015149873.1|4665983_4666304_-|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|143393
NC_019693.1|WP_015149867.1|4653308_4654793_-|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl|CDD|214599
NC_019693.1|WP_015149870.1|4656867_4664400_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_019693.1|WP_015149880.1|4673355_4674798_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149866.1|4651653_4653186_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270271
NC_019693.1|WP_015149874.1|4666366_4667182_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|132997
NC_019693.1|WP_015149868.1|4654878_4655793_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|215135
NC_019693.1|WP_015149881.1|4674902_4676300_-|TldD/PmbA-family-protein	unknown	unknown	gnl|CDD|223389
NC_019693.1|WP_015149875.1|4667337_4668948_+|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl|CDD|381169
NC_019693.1|WP_015149872.1|4665606_4665987_-|HEPN-domain-containing-protein	unknown	unknown	gnl|CDD|224807
NC_019693.1|WP_015149864.1|4649189_4649885_-|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl|CDD|223643
NC_019693.1|WP_015149871.1|4664542_4665382_+|FkbM-family-methyltransferase	unknown	unknown	gnl|CDD|273628
NC_019693.1|WP_015149863.1|4648448_4649042_-|sulfite-oxidase-like-oxidoreductase	unknown	unknown	gnl|CDD|239027
NC_019693.1|WP_015149862.1|4646954_4648334_+|aldehyde-dehydrogenase	unknown	unknown	gnl|CDD|143454

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015149865.1|4650100_4651435_-|TrkH-family-potassium-uptake-protein	gnl|CDD|273349	TIGR00933, Trk_system_potassium_uptake_protein_trkH., potassium uptake protein, TrkH family. The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds].	6.2183e-105
NC_019693.1|WP_015149869.1|4655852_4656830_+|homogentisate-phytyltransferase	gnl|CDD|183813	PRK12887, ubiA, tocopherol phytyltransferase; Reviewed.	2.47747e-163
NC_019693.1|WP_044197393.1|4672702_4673308_+|dephospho-CoA-kinase	gnl|CDD|184807	PRK14730, coaE, dephospho-CoA kinase; Provisional.	3.9467e-104
NC_019693.1|WP_015149877.1|4669795_4670431_+|S-layer-homology-domain-containing-protein	gnl|CDD|306825	pfam00395, SLH, S-layer homology domain.	1.50984e-09
NC_019693.1|WP_052315756.1|4670590_4672444_-|sulfatase	gnl|CDD|293754	cd16030, iduronate-2-sulfatase, iduronate-2-sulfatase. Iduronate 2-sulfatase is a sulfatase enzyme that catalyze the hydrolysis of sulfate ester bonds from a wide variety of substrates, including steroids, carbohydrates and proteins. Iduronate 2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in the iduronate 2-sulfatase gene that result in enzymatic deficiency lead to the sex-linked mucopolysaccharidosis type II, also known as Hunter syndrome.	0
NC_019693.1|WP_015149873.1|4665983_4666304_-|nucleotidyltransferase-domain-containing-protein	gnl|CDD|143393	cd05403, NT_KNTase_like, Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins. S. aureus KNTase is a plasmid encoded enzyme which confers resistance to a wide range of aminoglycoside antibiotics which have a 4'- or 4''-hydroxyl group in the equatorial position, such as kanamycin A. This enzyme transfers a nucleoside monophosphate group from a nucleotide (ATP,GTP, or UTP) to the 4'-hydroxyl group of kanamycin A. This enzyme is a homodimer, having two NT active sites. The nucleotide and antibiotic binding sites of each active site include residues from each monomer. Included in this subgroup is Escherichia coli AadA5 which confers resistance to the antibiotic spectinomycin and is a putative aminoglycoside-3'-adenylyltransferase. It is part of the aadA5 cassette of a class 1 integron. This subgroup also includes Haemophilus influenzae HI0073 which forms a 2:2 heterotetramer with an unrelated protein HI0074. Structurally HI0074 is related to the substrate-binding domain of S. aureus KNTase. The genes encoding HI0073 and HI0074 form an operon. Little is known about the substrate specificity or function of two-component NTs. The characterized members of this subgroup may not be representive of the function of this subgroup. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, co-ordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are conserved in this subgroup.	7.28909e-13
NC_019693.1|WP_015149867.1|4653308_4654793_-|methyl-accepting-chemotaxis-protein	gnl|CDD|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	5.15929e-41
NC_019693.1|WP_015149870.1|4656867_4664400_+|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.82251e-23
NC_019693.1|WP_015149866.1|4651653_4653186_-|ABC-transporter-substrate-binding-protein	gnl|CDD|270271	cd13553, PBP2_NrtA_CpmA_like, Substrate binding domain of ABC-type nitrate/bicarbonate transporters, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes nitrate (NrtA) and bicarbonate (CmpA) receptors. These domains are found in eubacterial perisplamic-binding proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. These binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.57713e-84
NC_019693.1|WP_015149874.1|4666366_4667182_-|glycosyltransferase-family-2-protein	gnl|CDD|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	0.00292496
NC_019693.1|WP_015149868.1|4654878_4655793_+|methyltransferase-domain-containing-protein	gnl|CDD|215135	PLN02244, PLN02244, tocopherol O-methyltransferase.	2.62255e-127
NC_019693.1|WP_015149881.1|4674902_4676300_-|TldD/PmbA-family-protein	gnl|CDD|223389	COG0312, TldD, Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only].	3.22297e-130
NC_019693.1|WP_015149875.1|4667337_4668948_+|uroporphyrinogen-III-C-methyltransferase	gnl|CDD|381169	cd11642, SUMT, Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT). SUMT is an enzyme of the cobalamin and siroheme biosynthetic pathway. It catalyzes the first of three steps leading to the formation of siroheme from uroporphyrinogen III; it transfers two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yield precorrin-2 via the intermediate formation of precorrin-1. Precorrin-2 is also a precursor for the biosynthesis of vitamin B12, coenzyme F430, siroheme and heme d1. This family includes proteins in which the SUMT domain is fused to other functional domains, such as to a uroporphyrinogen-III synthase domain to form bifunctional uroporphyrinogen-III methylase/uroporphyrinogen-III synthase, or to a dual function dehydrogenase-chelatase domain, as in the case of the multifunctional S-adenosyl-L-methionine (SAM)-dependent bismethyltransferase/dehydrogenase/ferrochelatase CysG, which catalyzes all three steps that transform uroporphyrinogen III into siroheme.	2.55356e-105
NC_019693.1|WP_015149872.1|4665606_4665987_-|HEPN-domain-containing-protein	gnl|CDD|224807	COG1895, COG1895, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN [Function unknown].	2.43447e-26
NC_019693.1|WP_015149864.1|4649189_4649885_-|TrkA-family-potassium-uptake-protein	gnl|CDD|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	7.26999e-67
NC_019693.1|WP_015149871.1|4664542_4665382_+|FkbM-family-methyltransferase	gnl|CDD|273628	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family. Members of this family are characterized by two well-conserved short regions separated by a variable in both sequence and length. The first of the two regions is found in a large number of proteins outside this subfamily, a number of which have been characterized as methyltransferases. One member of the present family, FkbM, was shown to be required for a specific methylation in the biosynthesis of the immunosuppressant FK506 in Streptomyces strain MA6548.	1.06587e-31
NC_019693.1|WP_015149863.1|4648448_4649042_-|sulfite-oxidase-like-oxidoreductase	gnl|CDD|239027	cd02109, arch_bact_SO_family_Moco, bacterial and archael members of the sulfite oxidase (SO) family of molybdopterin binding domains. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). Common features of all known members of this family are that they contain one single pterin cofactor and part of the coordination of the metal (Mo) is a cysteine ligand of the protein and that they catalyze the transfer of an oxygen to or from a lone pair of electrons on the substrate. The specific function of this subgroup is unknown.	8.20805e-98
NC_019693.1|WP_015149862.1|4646954_4648334_+|aldehyde-dehydrogenase	gnl|CDD|143454	cd07136, ALDH_YwdH-P39616, Bacillus subtilis aldehyde dehydrogenase ywdH-like. Uncharacterized Bacillus subtilis ywdH aldehyde dehydrogenase (locus P39616) most closely related to the ALDHs and fatty ALDHs of families 3 and 14, and similar sequences, are included in this CD.	0

Protein sequences

>NC_019693.1|WP_015149871.1|4664542_4665382_+|FkbM-family-methyltransferase
MTQTLPESSQKKPVNLLVRLNQDYHKLCLNLDISKYSQKIMWHYFSQGKFYEPEESKFLERVLKPGDNFIDIGAHIGYYSLLAAILVGETGRVISIEPDKTNIDWIQDHITLNQFPQMQVIPTVLGSETKPVEFFYNADNDGGHALWDVGLHEFNKISRSHRQTSTLPMTTLDEVVRDKGLTGVKLIKIDTEGAEHQILQGSLQTLTTYQVPYIIAEINRFALNKMGTDEKQLREFMATLGYSPYLLRNESPNWVKLSPDQYYNSQYVFNLVFALSDKL
>NC_019693.1|WP_015149870.1|4656867_4664400_+|tetratricopeptide-repeat-protein
MDVNQSVNPYSALSVSQCLEMAQKQCETGNFAQAQTLCREILHREPENLLALNLLGTIASQQGDNLGAISWYQQAVKIHPNVPEFHYNLANSLKLEGQKEEAIAHYQQAITLRPNYTKACYNLGNLHLERGEIQAAIAQYQQAFTLDPQDPQIQTNLGNALKEAGDLEAAVAQYRQVCDRCPDSAEFHYNLGVALHDYGDLAEAVACYNRAIAIEPHTVMYHWNRALSLLISGDYPQGFIEYEWRWQTETLQPRPFSQPIWDGSPLTGRTILLHSEQGIGDTLQFIRYIPLVAALGGRVILECYPPLFPLLQQLKDVDILVVRDEPLPAFDVHAPLMSLPRIFGTTLETIPREIPYLMVRPPHSSRLDIQEHRPSSPHPGRVGLYEQSPPARADVSLANHEHNTSDSPLLKGGSGASLLNASPESLNPSPSFKIGIVWAANHENPTAIKRSCPLSYFLQLIEEFATASIGFYSLQKDSNELTELSPQVLIQDLAPQLNHFRDTAEVMAELDLIITVDTAAAHLAGALGKPAWVLLPFAPDWRWLLHRPDSPWYPTLRLFRQSKPGDWQSVFDEVKQALIETGELTENWAKMPQKVSAKLGRGIVSHQEGNLTAAERLYRQVLAEIPNHPVALTNLGMLLKAEGNCQEAVTCYHRALPYAPQEVGLHYNLGNALWELGNRFAAIAQFHRVIVLQPNHVEGYNNLGMVLHELGELEPAIPHFEQAITLNPNYAQGYNNLGLVLQDLGRVEEAIACYNTALRLQPNYAEAHNNRGIALLIQGNLRQGFRDYEWRWRVKAAPDLPPIPAPFWDGSDLQGKTILLHAEQGLGDCIQFIRYAALLVQRGGRVVALVNKPLVRLFKSVPGIDRVSGYWSELAPIDVWIPLLSLPHILETTLATVPGKIPYLAPTHLAPVILDAPGFKVGIVWAGNPKHKGDRTRSCPLRYFLPLLNIPGIKWYSLQKGQEETRIRQQNLPIHDLAPHLQDLADTAAVIAQLDLVITVDTSVAHLAGALGKPVWVALSYAPDWRWLLNRSDSPWYPTMRLFRQQERGDWQGVFDEVAQCLTEVVGTRGVFAEPPTISPEFALARQDYESGNFADAQRRCRVLLRQSPNQAQGWQLLGAIAHQGGKLNTAVGYYKQAIVADCRYLPAYINLGATLRSLGRTSEAISYLAQAIAVDSHCLAAHYNLGNALSDEGNFQEATAHYRQVIALDAHHSQAHYHLGNALKELGNVTEAIAQIQEATALDPNYTEAHNTLGNLFLKAGRITEAMACFQRATALDSQYIDAQINLGIALQEQHQTPAAIGTYHRALQIQPDSAEAHLNLALSLLIAGDLRGGFAEYEWRWRVKGYPALPHFEVPRWEGEDLTGKTLLLYGEQGLGDTLQFIRYSTLLAQQGIRVVALVAAPLVSILKTVSGIDAISSHPEELKPFDSWIPLMSLPRIFGTTLTTIPSTIPYLQPPYSRQLSFESTKFKVEHLNVFKRPNPPAPFPKREGGAGKGSFKAPPLLGEGFGERSDWFSGNIEMLPFKVGIVWAGNPKHHSDYKRSCSLDVFQSFLTVPGVQFYSLQKGQAGETWQGKNLPLQDLGPTLHNFADTAAAISQLDLIITVDTAIAHLAGAMGKPTWLLLAYTPDWRWGLEGTDSPWYPSLRLFRQKQPGDWQEVGDRIAQELRQTVANFSTQPLNVAEENQETLEQFQQMIASHPNSAQAYYNLGNFLKKQHQPEAAIAQYHQAIALNPNYLNAYFNLGNTYLELNQPEEAIAQYETALTIAPDDADTHTNLGFALLMTGDYSRGFAEYEWRNQRQDETSHSSLLPSWDGSDFSGRTLLLYTELGFGDSIQFIRYLPQVAQRGGRVILQCPESLIKLFSTLPCDRLIPTGEPLPPFDITASLMSLPYLLGTTLDTIPTTVPYLTPPNPPSIILKSPHFKVGIVWAGSPRYGNQRNRSCPVDYLLPLGEIPGVTLYSLQKGQFLENPPATLTDLAPQLEDFADTAGAITQLDLVITIDTAVAHLAGALGKPVWVLLPFAPDWRWMRDRSDSPWYPTLRLFRQTQPGNWQEVCDRIAQELRQTVENSAQVGIPEHNPSLPGKKWLEGEVRRNPKSMRTESIGDRTQPVAKPSQKPLRLGLAWPINQMTGWGIYGTNLTLQLQKKPGYEPMLLLQPDTSGVVNPLMRSQLKPACDRYQNLEQLRNQNPGKPIWCDFPVLHALGNNFISLATTQQLSGKQNIGLIFFEDTHLTPEKRQLAQEYLLIVAGSTWNAEVLKSQGIPTVQALPQGIDPTLFHPAPKSNLLGDRFVIFSGGKLEYRKGQDIVIAAFKTFQKRHPEALLLTAWHNFWPQFMRGLQTTGHVKGLPQIGADKRLNITDWLLNNGLNPDSFIDIGAIPNYLMPQIIREADCALFTNRCEGGTNLVAMETMACGIPTILSANTGHLDLIDPNHCYPLKTQKSVQPTPQFIGVEGWGESDIEEIIETLETIYQNRETAKQKGIIAAQFMQQWTWENQVDRLLEILGEIL
>NC_019693.1|WP_015149869.1|4655852_4656830_+|homogentisate-phytyltransferase
MSQLSPSPPKVSQPAEMNVVQKYAPWLYSFWKFTRPHTIIGTSLSAIGLFAIAWAFSGDSLTGKALLPLFGTWFTCLCGNVYIVGLNQLFDIEIDQINKPELPVAAGEFTQRQGQIIVGITGILAVALAALQGPWLLATVLISLGLGTVYSLPPIRLKRFPFWASFCIFTVRGIIVNLGLFLHYQWVMPGSGGVMIPPSVWALTLFVLGFTFAIAIFKDIPDMEGDRLYQISTLTLRLGARTVFDLARWVIVFCYIATSVAAFLWLPQVNPFVLAIAHGVALTGLWWRSRLVDLEDKVAIAACYQFIWKLFFLEYIMFPVACLLA
>NC_019693.1|WP_015149868.1|4654878_4655793_+|methyltransferase-domain-containing-protein
MTTSNLYEQIQQFYDASSGLWERVWGEHMHHGYYGERGDRQLDRRQAQIDLIEELLAWTGLQLSQDLNDQVSTILDVGCGIGGSSLYLAQKFNASATGITLSPVQAARATERAREAGIPTSSGLEGGSMTPGPRAEFRVANALELPFADNSFDLVWTLESGEHMPDKKQFLQECYRVLAPGGALMMATWCHRPVAPPAAPLSDRERHQLMEIYKVYCLPYVISLPEYETIAREIGFQGIQVADWSEAVAPFWDLVIDSAFDPSALLGLLFSGWQTIQGALALGLMRDGYKQGLIRYGLLCGTKS
>NC_019693.1|WP_015149867.1|4653308_4654793_-|methyl-accepting-chemotaxis-protein
MLVKRAPFIGDFSKMKVTHQIFGGYAVPIFLSVCAAILVYFNGVRRVNDASEQLDAVRVRVDEVEALAYSILAMQRASRAYIISRDINELEGYEQWDNTFYEQSEKLRYLIQSPDQRETLKQIIELGDRVNEFDRRLISYIELSKVNKADQTARSGEGKLAANRLKELVEQFTSTEQVILAQRNQERADALMFLSQVVFGTAGVTALLGMTIGAKISTAIGQKMNQQAAAIAQSAAEIAATIAQQERSAAFQSAATTETTTHLDRLSCSSQQAAEETTHSSACADRALTLANQGATAVSQTLGAMATLEQKVQDIAGKIGCLNQQTHQIADIAQLVGQLATQTNMLALNAAIEAIRAGDKGKGFGVVATEIRKLADRSKESADKIHILLADIEATLGSTIKVAQEGTTTVTASSQITQQTAEAFQGVRGAINEVVASTAEIALVAKQQATAIHEVLDATNTIDISARENAAGITQVKIAIQQLNDAAQELQAMV
>NC_019693.1|WP_015149866.1|4651653_4653186_-|ABC-transporter-substrate-binding-protein
MFQTHPLLRQNHPNFNSFFCSCGRVHSSRNCDINPPADVLNLREVWQKFSRPSVSERVTGNPQGAELFSGNTELEQWAAEAIAQVGGLDAVMASAYGVDPEGGIRDTLLDSPFTRRKFLQQVAIAAALTVATNCAIPEPEESDSSPVSRLEKTDLKIGFIPITCATPIIMSQPLGFYEKYGLNVELVKMESWEQVRDSAMAGELDAYHMLSPMPIAMTLGLGSQPFPVKLASIENINGQAIVLALKYQDKVKEAKDFKGLTLGIPFRYSMHNLLLRYYLASNNINPDRDLNLKLVPPPQAIELMKAGEIDGFLMPDGNAQQAVYEKAGFIYLLTKELWDGHPCCSFAASKPWIDEHPSTFRALNKAIIDGCNYARNPENRLEIAQAIAAPEYLNQPQSVLEAVLTGTFDDGLGNVQTVSDRIDFDPYPWKSFSYWITSQFARWGMLDGQNISHEAIADEVFLTGLARQLAKQLGQSPPTIILRDEQLKFGIFDPSEPDAYRQAQIQKHGF
>NC_019693.1|WP_015149865.1|4650100_4651435_-|TrkH-family-potassium-uptake-protein
MTVARTICLGFLVIIAIGTILLLLPVSTSDGTWNNFVTALFTATSAVCVTGLIVVDTGTHYSGLGEFFIVLLIQLGGLGYMTANTFLLLLLGRRLGLRDRVAIQQSLDTTEMSGVVPLVRSIVAMTLVFELTGMFLLLFIFSPDFGFNDSLWLSIFHSISAFNNAGFSLFADSLMAYAGSIPMNLVITFLVIFGGIGYQVIMEMYMWVRDRISRNPERVVFSLHFKIVTSTTLLLLILGTIAFFFTESSNSRTLGNADFLERLLSAWFQSVITRTAGFNTIDFGQMTTAALFITIALMFIGASPGSTGGGIKTTTVRVLASCTRSVLQGRNQVLCFERQIPPELILKAVAVVLSSLGVVVVATILLAITDPNIEFIQLFFEVISAFATVGLSMGITGNLSTLGQLVIIVTMYVGRVGMVMLMSAMIGDPKPSNIRYPEENLLVG
>NC_019693.1|WP_015149864.1|4649189_4649885_-|TrkA-family-potassium-uptake-protein
MNLSSLNFFRNLRSDNKQFAVIGLGRFGRAVCDTLHGLGYEVLAIDVDEKKVTQAVSEQIAAHALQLDTTEPSAIQQAGMTDFDTVIVAIGNFLAQSIITTLNLKEAGVKHVVAKASSEIHMKLLKKVGADHVVFPEREMGCALARTITTPSILDRFELDPEHSIVETIVPPTFHGKTIAELELRNRYGLNVLAVSQDEKFEINPPANRRLLGGTVMVVIGANKAIDRLRP
>NC_019693.1|WP_015149863.1|4648448_4649042_-|sulfite-oxidase-like-oxidoreductase
MLGKYFKKPSAELSDRVPPGQHLATGFPVLTYGDTPQISRDRYSLKVWGLVDPQTFTWDDLMAMPQEEFTADFHCVTHWSKLDVKWTGIKVLDFMKHLSVDEKAICIMEHCYGGYTTNIAIADFLREENFFAHTLFGEPLSPEHGGPLRLVVPHLYAWKSAKWINGLEFIEEEASGFWERNGYHRRGEPWAEERYSY
>NC_019693.1|WP_015149862.1|4646954_4648334_+|aldehyde-dehydrogenase
MLTTARIRDVIEAQRQFFATGKTKDLDFRIEQLQRLKQALIDSKELVINALNKDLKKSEFEAYLMELGGIREINYVLKHIKSWTKPKTVARPLDQFPSVARIYPDPLGVVLIVSPWNYPFSLTISPLIGAIAAGNCITLKPSEIAPHTSHLVADLIRKIFDPSYIAVVEGGVEVSQDLLSQKFDHIFFTGGTQIGRIVMEAAAKHLTPVTLELGGKSPCIVEADIDLPTACKRIVWGKFINAGQTCIAPDYLLVNRRIKRDLLVGIERTITEFFGQNPANSPDYGRIINDKQFERLRGLLQDGEIRVGGQTDAGDRYIAPTVLDGVSLTSPIMQEEIFGPILPVLDYDKLDQAIAVINQKPKPLALYLFSKDHQTQQQVLRETSSGGVCLNDTIMHLAVSKLPFGGVGESGMGSYHGKASFDTFSHSKSVLEKSFRFDLDLRYPPYKNKLALIKRLIGG
>NC_019693.1|WP_015149872.1|4665606_4665987_-|HEPN-domain-containing-protein
MIPEQIALLKKAQNSLQAAKLLLDNHLYDISASRAYYTMFYVAEAFLLGDGLAFSSHAAVISALGRDFARTGRIPVEFHRYLIDAQNKRNQADYDINTEITASQANEQINHAEQFLKLAENQLGPL
>NC_019693.1|WP_015149873.1|4665983_4666304_-|nucleotidyltransferase-domain-containing-protein
MQNTCSTLLPTLRTYFQTLYGKKLEQLILYGSQARGDAKPDSDIDILVILTDPVDAWNEIDRTSQFIADLCLEHTVVISTAFVSSHRFQQEKSPFFLNVHREGVPL
>NC_019693.1|WP_015149874.1|4666366_4667182_-|glycosyltransferase-family-2-protein
MSTQQQTISLLCPTRGRPEQALRLALSVLNTASQPQRVELLFYVDNDDRKQSEYLEQFKTHKPKLDRFRRCGFLLGEAIGISKAWNELASRCEGNLLIMAADDQTYNDFGWDSRLDMETQKYPDEIFCMWFNEGHWQEKLCTFPIVSRKWCQTLGYFTTGLFECLYDDMWIWEIAKRVGRLHYIPDILTEHLHWGYGKAELDETYQHKQVDADKKLKPAVYRDMDLYCRTVPYRETDARRIAAVMQGQVFLYPVQLMVPGKSTIFDRRDKD
>NC_019693.1|WP_015149875.1|4667337_4668948_+|uroporphyrinogen-III-C-methyltransferase
MTETGGIVYLVGAGPGDAAYLTVRSRQLLAEAEAVVYDALIDEQLLQLAPAGCQRIHVGKRGGQPSWQQADIDRLLVAQCQQGKRVVRLKSGDPFIFGRCTEEIQALKAARCPYEVIPGISSALAGPLLAGIPLTDPVMSHSFTVVTGHDCDRLDWETLTRTPTLVILMGTRQLDEILRQLLQHGKSPQTPIAIIRACGTSRQFVWTGTFADIRDRTRGESLSPAVIVIGEVVKLRDYLLPDSPSRRPLSPDSADSVSMSNYSSHAAKSSPHSASGLGGKTVLVTRSAGQSSTFTEMLTDVGATVIEMPALEIRPPSSWESLDSAIAQISEFDWLILTSANAVDYFCDRLLAKGKDTRILAGVKIAVVGKKTAATLQQRSLTADYIPPDFVADSLVEQFPEDVSGQKILFPRVETGGREVLVAEFTTQGAIVEEVAAYESGCPDAIAPEAWKALQQRRIDIVTFASSKTVRNFCQLLDRQSRSGDQPWHSLLNNVRIASIGPQTSKTCYELLGRVDVEAQEYTLDGLLQALQSGNG
>NC_019693.1|WP_015149876.1|4669007_4669193_-|hypothetical-protein
MMQVTATVRDMFINASLSQQISFHDWVLLNALPESNLSQEERRMIKRLMHSVRRGWFRVLS
>NC_019693.1|WP_015149877.1|4669795_4670431_+|S-layer-homology-domain-containing-protein
MKKILTLVSVTLLLQSLIISVRAQQPVNPIQVVLESGLMTQYPDGQFHPERGVIRAELASILVKTFQLDKRTTATNQNQPIPDVPPSHWAYKDIEIALETGIMKGDLTGRFHPNQPVSRAEGFAIFAQAFGVLMLNDADVNRILTSYQDGYQTPDWARQALATAIFEELVNISNNNALNPLQPMTRADMAYALSQYLAKQNNPGTIPDIPN
>NC_019693.1|WP_052315756.1|4670590_4672444_-|sulfatase
MSAATVGLSQISCNAKSSEKSNVLFLAIDDLRPQIQSYGEAQMLTPNLDKLADRGVLFERAYCQIPVCGASRLSVMTGARPNKSPGEPVGRFWSYNSRLDEPVQNWHGNLEPAGINRPKTPEGNPAPTLPMLFKQQGYNTQSVGKIYHVMDDDLDAWNYGMTRFKDIRVYNIPGNEMNAYEIGENQPDNAYPDGITRDLAIAALRNLKEQQKPFFLALGFVKPHLPFNCPKKYWDMYDRNTIELAQNPFAPTDAPAESLHTWGELRRYQNLVFSDETKSQLDEEYARTLIHGYYACTTFVDSCIGSVLDELERLGLRDNTIIVVWGDHGFLLGEHNLWTKHTNYEIALRVPLIIDAPGKVKAAKTSALVELVDIYPTLCELVGIETPQHLEGTSLVPLLNNPQRPWKGAVFSRYEYGDTVLTDHYNYTEYIDVEDNFLSRMLYDRHLDPLETRNIANLPENAALVETLSELLAIGWKRAAVFGNSNFPIPFDVLPDGTIIVPDSISRSKSPQLFSASPRVSLKAKEIEILNKQATLSMGSQKDLTFQLESGDRFQIARLWLVEKQDPTKEAIGVEIMVNQSTVGRWSSPKPGDYFYQLQLKKSNENYLIKTGTFKLV
>NC_019693.1|WP_044197393.1|4672702_4673308_+|dephospho-CoA-kinase
MDKRKIGLTGGIATGKTTVSNYLKNQHQLPVFDADIYAREAVRIGSEVLNQIVKRYGSDLLLSDRSLNRQKLGEIVFTQPQEKQWLEEQIHPQVRDRFFREIAALPEQSTAVLVIPLLFEAQMTDLVTEIWVVSCPGDRQIQRLMERDGLTLDQARARINSQMPLSEKCSRADVILDNSSTVEHLIQQIDVALMQDRDNRK
>NC_019693.1|WP_015149880.1|4673355_4674798_+|hypothetical-protein
MQTIKTANPEVPPNTGGPIDWFKKFMAILAVINLLLVGFDSSYIPLRDIYFQQLPPVVIAYDQVKGIEPHPETEKYLQTVHQLTLELQQPQSSLETPQVENLLESLRHESEGMLNENPFMAAGKFGTFAKIQRRMRQHLGTEYASEAFQTFWTSSYLSTHNLSQELNFFQSQINPLIASNYFRNVDEIGQVVDEFWRIDIFFMCLFGLEFLLRTFFRHRRVSGLRWIDAMLRRWYDVLLFLPFWRGLRVIPVAVRLQQSELFNFDRILVQMTHEPAARLADRLSRFVMVRFINQAQDSIREGTAAQSLLNPQAAIDLNNVNEIEVITDRLLELTIYKVLPQIKPELEAVLHHSIEGAFKDSGVYQSLKSLPGLGNLPTDFTEQMASSLAQTTVTVLETSYADVEGRVLFDRLSQQFNQAFRKALGDRKTQEEIQILLTDFLEELKLNYVVKSTHSDPEATLAEIENLYQPEEPPSLPSVQ
>NC_019693.1|WP_015149881.1|4674902_4676300_-|TldD/PmbA-family-protein
MSTLLADAKNLLAELIARYASRVDYLAIRLEEAEGTDIFLRGEKIETLSEGVSIGGQVRACYQGGWGFASFNQLAGLAERIEEAIAAARLVGDEETILAPVDPVQITCELLLTGTDPRKIPIIDKKRLCDRYTDILRQVDPRITTTSVRYSDSAQRILLFTSEGTILEQSWVDMEMRFAATARNGETVQTGRETTGSRKAYEDLIQLDTQVRGAAQRAVEALSLPSVKGNTYQVVIDPILSGLFVHEAFGHLSEADMAYENPDLLEVMTLGRRFGPEDLQIFDGAAPPGHRGSYLYDDEGTPATTTQLIKDGVLVGRLHSRETAGKLEETATGNARCLNYHYPPIVRMTNTWIERGKTPVQDLFTDIQEGVYARNWLGGMTNGEMFTFSAGEAWMIRKGQLAEPVRDVTLSGNVFSTLADIEAIGDDFYWDESGGCGKGGQNGLPVGCGGPSLRIRNVVVGGESA

Crispr_ID: NC_019693_44

• CRISPR_ID: NC_019693_44
• CRISPR_location: 4678711-4678844
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_44

Consensus_repeat	Method
GTCCTAGGGTGAGGGTTGAGAAACCGGGTTTCTTTCATCAACTTAGGCAA	CRISPRCasFinder

spacers of NC_019693_44

>44.1|4678761|34|NC_019693|CRISPRCasFinder
TCCACCCACAATTGTCGCAGAAACCCGGTTTCTA

CRISPR arrays and Neighbor proteins around NC_019693_44

CRISPR arrays

The CRISPR arrays of NC_019693_44

>merge|NC_019693|44|4678711-4678844|CRISPRCasFinder
GTCCTAGGGTGAGGGTTGAGAAACCGGGTTTCTTTCATCAACTTAGGCAATCCACCCACAATTGTCGCAGAAACCCGGTTTCTAGTCCTAGGGTGAGGGTTGAGAAACCGGGTTTCTTTCATCAATTTAGGCAA

>NC_019693|44|43|4678711-4678844|CRISPRCasFinder
GTCCTAGGGTGAGGGTTGAGAAACCGGGTTTCTTTCATCAACTTAGGCAA	TCCACCCACAATTGTCGCAGAAACCCGGTTTCTA
GTCCTAGGGTGAGGGTTGAGAAACCGGGTTTCTTTCATCAATTTAGGCAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015149887.1|4685060_4686368_+|exonuclease-subunit-SbcD	unknown	unknown	gnl|CDD|273178
NC_019693.1|WP_015149885.1|4683166_4683463_-|glutaredoxin-family-protein	unknown	unknown	gnl|CDD|368604
NC_019693.1|WP_015149873.1|4665983_4666304_-|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|143393
NC_019693.1|WP_044197393.1|4672702_4673308_+|dephospho-CoA-kinase	unknown	unknown	gnl|CDD|184807
NC_019693.1|WP_015149877.1|4669795_4670431_+|S-layer-homology-domain-containing-protein	unknown	unknown	gnl|CDD|306825
NC_019693.1|WP_052315756.1|4670590_4672444_-|sulfatase	unknown	unknown	gnl|CDD|293754
NC_019693.1|WP_015149884.1|4681450_4682944_-|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	unknown	unknown	gnl|CDD|234660
NC_019693.1|WP_156824072.1|4690251_4690467_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_052315758.1|4686486_4687086_+|hypothetical-protein	unknown	unknown	gnl|CDD|226459
NC_019693.1|WP_015149882.1|4676653_4678450_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_019693.1|WP_015149880.1|4673355_4674798_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149874.1|4666366_4667182_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|132997
NC_019693.1|WP_015149881.1|4674902_4676300_-|TldD/PmbA-family-protein	unknown	unknown	gnl|CDD|223389
NC_019693.1|WP_015149875.1|4667337_4668948_+|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl|CDD|381169
NC_019693.1|WP_015149889.1|4689099_4690071_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381319
NC_019693.1|WP_052315759.1|4688223_4689027_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|226459
NC_019693.1|WP_044197399.1|4684209_4684944_+|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl|CDD|131112
NC_019693.1|WP_015149888.1|4687120_4688143_+|IS4-family-transposase	unknown	unknown	gnl|CDD|376573
NC_019693.1|WP_015149883.1|4679129_4680830_-|signal-transduction-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_019693.1|WP_015149876.1|4669007_4669193_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015149887.1|4685060_4686368_+|exonuclease-subunit-SbcD	gnl|CDD|273178	TIGR00619, Nuclease_SbcCD_subunit_D, exonuclease SbcD. All proteins in this family for which functions are known are double-stranded DNA exonuclease (as part of a complex with SbcC homologs). This complex functions in the initiation of recombination and recombinational repair and is particularly important in regulating the stability of DNA sections that can form secondary structures. This family is likely homologous to the MRE11 family. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	5.54617e-76
NC_019693.1|WP_015149873.1|4665983_4666304_-|nucleotidyltransferase-domain-containing-protein	gnl|CDD|143393	cd05403, NT_KNTase_like, Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins. S. aureus KNTase is a plasmid encoded enzyme which confers resistance to a wide range of aminoglycoside antibiotics which have a 4'- or 4''-hydroxyl group in the equatorial position, such as kanamycin A. This enzyme transfers a nucleoside monophosphate group from a nucleotide (ATP,GTP, or UTP) to the 4'-hydroxyl group of kanamycin A. This enzyme is a homodimer, having two NT active sites. The nucleotide and antibiotic binding sites of each active site include residues from each monomer. Included in this subgroup is Escherichia coli AadA5 which confers resistance to the antibiotic spectinomycin and is a putative aminoglycoside-3'-adenylyltransferase. It is part of the aadA5 cassette of a class 1 integron. This subgroup also includes Haemophilus influenzae HI0073 which forms a 2:2 heterotetramer with an unrelated protein HI0074. Structurally HI0074 is related to the substrate-binding domain of S. aureus KNTase. The genes encoding HI0073 and HI0074 form an operon. Little is known about the substrate specificity or function of two-component NTs. The characterized members of this subgroup may not be representive of the function of this subgroup. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, co-ordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are conserved in this subgroup.	7.28909e-13
NC_019693.1|WP_044197393.1|4672702_4673308_+|dephospho-CoA-kinase	gnl|CDD|184807	PRK14730, coaE, dephospho-CoA kinase; Provisional.	3.9467e-104
NC_019693.1|WP_015149877.1|4669795_4670431_+|S-layer-homology-domain-containing-protein	gnl|CDD|306825	pfam00395, SLH, S-layer homology domain.	1.50984e-09
NC_019693.1|WP_052315756.1|4670590_4672444_-|sulfatase	gnl|CDD|293754	cd16030, iduronate-2-sulfatase, iduronate-2-sulfatase. Iduronate 2-sulfatase is a sulfatase enzyme that catalyze the hydrolysis of sulfate ester bonds from a wide variety of substrates, including steroids, carbohydrates and proteins. Iduronate 2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in the iduronate 2-sulfatase gene that result in enzymatic deficiency lead to the sex-linked mucopolysaccharidosis type II, also known as Hunter syndrome.	0
NC_019693.1|WP_015149884.1|4681450_4682944_-|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	gnl|CDD|234660	PRK00139, murE, UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional.	0
NC_019693.1|WP_052315758.1|4686486_4687086_+|hypothetical-protein	gnl|CDD|226459	COG3950, COG3950, Predicted ATP-binding protein involved in virulence [General function prediction only].	1.69939e-06
NC_019693.1|WP_015149882.1|4676653_4678450_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.44432e-17
NC_019693.1|WP_015149889.1|4689099_4690071_-|aldo/keto-reductase	gnl|CDD|381319	cd19093, AKR_AtPLR-like, Arabidopsis thaliana pyridoxal reductase (PLR) and similar proteins. Arabidopsis thaliana PLR (EC 1.1.1.65) is the prototype of this family. It catalyzes the reduction of pyridoxal (PL) with NADPH and oxidation of pyridoxine (PN) with NADP(+), and is involved in the PLP salvage pathway.	7.75184e-152
NC_019693.1|WP_015149874.1|4666366_4667182_-|glycosyltransferase-family-2-protein	gnl|CDD|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	0.00292496
NC_019693.1|WP_015149881.1|4674902_4676300_-|TldD/PmbA-family-protein	gnl|CDD|223389	COG0312, TldD, Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only].	3.22297e-130
NC_019693.1|WP_015149875.1|4667337_4668948_+|uroporphyrinogen-III-C-methyltransferase	gnl|CDD|381169	cd11642, SUMT, Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT). SUMT is an enzyme of the cobalamin and siroheme biosynthetic pathway. It catalyzes the first of three steps leading to the formation of siroheme from uroporphyrinogen III; it transfers two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yield precorrin-2 via the intermediate formation of precorrin-1. Precorrin-2 is also a precursor for the biosynthesis of vitamin B12, coenzyme F430, siroheme and heme d1. This family includes proteins in which the SUMT domain is fused to other functional domains, such as to a uroporphyrinogen-III synthase domain to form bifunctional uroporphyrinogen-III methylase/uroporphyrinogen-III synthase, or to a dual function dehydrogenase-chelatase domain, as in the case of the multifunctional S-adenosyl-L-methionine (SAM)-dependent bismethyltransferase/dehydrogenase/ferrochelatase CysG, which catalyzes all three steps that transform uroporphyrinogen III into siroheme.	2.55356e-105
NC_019693.1|WP_052315759.1|4688223_4689027_+|AAA-family-ATPase	gnl|CDD|226459	COG3950, COG3950, Predicted ATP-binding protein involved in virulence [General function prediction only].	9.36766e-17
NC_019693.1|WP_044197399.1|4684209_4684944_+|phosphoadenosine-phosphosulfate-reductase	gnl|CDD|131112	TIGR02057, Phosphoadenosine_phosphosulfate_reductase, phosphoadenosine phosphosulfate reductase, thioredoxin dependent. Requiring thioredoxin as an electron donor, phosphoadenosine phosphosulfate reductase catalyzes the reduction of 3'-phosphoadenylylsulfate (PAPS) to sulfite and phospho-adenosine-phosphate (PAP). Found in enterobacteria, cyanobacteria, and yeast, PAPS reductase is related to a group of plant (TIGR00424) and bacterial (TIGR02055) enzymes preferring 5'-adenylylsulfate (APS) over PAPS as a substrate for reduction to sulfite. [Central intermediary metabolism, Sulfur metabolism].	6.51312e-105
NC_019693.1|WP_015149888.1|4687120_4688143_+|IS4-family-transposase	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	1.31902e-16
NC_019693.1|WP_015149883.1|4679129_4680830_-|signal-transduction-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.28085e-52
NC_019693.1|WP_015149885.1|4683166_4683463_-|glutaredoxin-family-protein	gnl|CDD|368604	pfam05768, DUF836, Glutaredoxin-like domain (DUF836). These proteins are related to the pfam00462 family.	3.27641e-22

Protein sequences

>NC_019693.1|WP_015149882.1|4676653_4678450_+|HAMP-domain-containing-histidine-kinase
MYKWVLPTISEVLAQAGKADNSSDPGMGLTGEDPGDRNGPTPRPDAATVWLRRIRADRQWQGAVASVCSLLDGELAGDHPDTHNPLSTKGLVLSGPVPVLTQSPHLEQFSTWTFAGVQQSGAGLSSSLFFPTTDSGSDAPNPTVLPLLTGDPLAREQFCLVLTARFSLVMLVGLNPQGQPAFQFSFDPETIALVWQGLRSRLLPFKNQTAISTLDQQFQRFHPCTPDYKIVCQFTQQLLEYLPDPLELDREMLNEMETFAADWTGWGSSMRALPQSGEDCPNGEAEICWEVSRPDGNSRVSTSGERRTALNNPDPGTAKTLRSKGGKAVGTVSAKTANPRKPAIDQPLDDLRDAASKNVRNQAPALDVELLQAIAHEVRTPLATIRTLTRLLLKRRHLDAEIIKRLEAIDRECSEQIDRFGLFFRAVELETTKDAHAPVHLTSTSLTQVLNSCIPRWEKQASRRNLTLDVILPQKMPSVVSDPSLLDQVLTGAIDNFTSTLPAGGKLRVEISLAGHQLKVELHSQTHASVNSEPSVSGTQALKSLGQMLMFQPETGNLSLNLSVTKNLFQALGGKLIVRNRHQHGQVLTIFLPLEMRG
>NC_019693.1|WP_015149881.1|4674902_4676300_-|TldD/PmbA-family-protein
MSTLLADAKNLLAELIARYASRVDYLAIRLEEAEGTDIFLRGEKIETLSEGVSIGGQVRACYQGGWGFASFNQLAGLAERIEEAIAAARLVGDEETILAPVDPVQITCELLLTGTDPRKIPIIDKKRLCDRYTDILRQVDPRITTTSVRYSDSAQRILLFTSEGTILEQSWVDMEMRFAATARNGETVQTGRETTGSRKAYEDLIQLDTQVRGAAQRAVEALSLPSVKGNTYQVVIDPILSGLFVHEAFGHLSEADMAYENPDLLEVMTLGRRFGPEDLQIFDGAAPPGHRGSYLYDDEGTPATTTQLIKDGVLVGRLHSRETAGKLEETATGNARCLNYHYPPIVRMTNTWIERGKTPVQDLFTDIQEGVYARNWLGGMTNGEMFTFSAGEAWMIRKGQLAEPVRDVTLSGNVFSTLADIEAIGDDFYWDESGGCGKGGQNGLPVGCGGPSLRIRNVVVGGESA
>NC_019693.1|WP_015149880.1|4673355_4674798_+|hypothetical-protein
MQTIKTANPEVPPNTGGPIDWFKKFMAILAVINLLLVGFDSSYIPLRDIYFQQLPPVVIAYDQVKGIEPHPETEKYLQTVHQLTLELQQPQSSLETPQVENLLESLRHESEGMLNENPFMAAGKFGTFAKIQRRMRQHLGTEYASEAFQTFWTSSYLSTHNLSQELNFFQSQINPLIASNYFRNVDEIGQVVDEFWRIDIFFMCLFGLEFLLRTFFRHRRVSGLRWIDAMLRRWYDVLLFLPFWRGLRVIPVAVRLQQSELFNFDRILVQMTHEPAARLADRLSRFVMVRFINQAQDSIREGTAAQSLLNPQAAIDLNNVNEIEVITDRLLELTIYKVLPQIKPELEAVLHHSIEGAFKDSGVYQSLKSLPGLGNLPTDFTEQMASSLAQTTVTVLETSYADVEGRVLFDRLSQQFNQAFRKALGDRKTQEEIQILLTDFLEELKLNYVVKSTHSDPEATLAEIENLYQPEEPPSLPSVQ
>NC_019693.1|WP_044197393.1|4672702_4673308_+|dephospho-CoA-kinase
MDKRKIGLTGGIATGKTTVSNYLKNQHQLPVFDADIYAREAVRIGSEVLNQIVKRYGSDLLLSDRSLNRQKLGEIVFTQPQEKQWLEEQIHPQVRDRFFREIAALPEQSTAVLVIPLLFEAQMTDLVTEIWVVSCPGDRQIQRLMERDGLTLDQARARINSQMPLSEKCSRADVILDNSSTVEHLIQQIDVALMQDRDNRK
>NC_019693.1|WP_052315756.1|4670590_4672444_-|sulfatase
MSAATVGLSQISCNAKSSEKSNVLFLAIDDLRPQIQSYGEAQMLTPNLDKLADRGVLFERAYCQIPVCGASRLSVMTGARPNKSPGEPVGRFWSYNSRLDEPVQNWHGNLEPAGINRPKTPEGNPAPTLPMLFKQQGYNTQSVGKIYHVMDDDLDAWNYGMTRFKDIRVYNIPGNEMNAYEIGENQPDNAYPDGITRDLAIAALRNLKEQQKPFFLALGFVKPHLPFNCPKKYWDMYDRNTIELAQNPFAPTDAPAESLHTWGELRRYQNLVFSDETKSQLDEEYARTLIHGYYACTTFVDSCIGSVLDELERLGLRDNTIIVVWGDHGFLLGEHNLWTKHTNYEIALRVPLIIDAPGKVKAAKTSALVELVDIYPTLCELVGIETPQHLEGTSLVPLLNNPQRPWKGAVFSRYEYGDTVLTDHYNYTEYIDVEDNFLSRMLYDRHLDPLETRNIANLPENAALVETLSELLAIGWKRAAVFGNSNFPIPFDVLPDGTIIVPDSISRSKSPQLFSASPRVSLKAKEIEILNKQATLSMGSQKDLTFQLESGDRFQIARLWLVEKQDPTKEAIGVEIMVNQSTVGRWSSPKPGDYFYQLQLKKSNENYLIKTGTFKLV
>NC_019693.1|WP_015149877.1|4669795_4670431_+|S-layer-homology-domain-containing-protein
MKKILTLVSVTLLLQSLIISVRAQQPVNPIQVVLESGLMTQYPDGQFHPERGVIRAELASILVKTFQLDKRTTATNQNQPIPDVPPSHWAYKDIEIALETGIMKGDLTGRFHPNQPVSRAEGFAIFAQAFGVLMLNDADVNRILTSYQDGYQTPDWARQALATAIFEELVNISNNNALNPLQPMTRADMAYALSQYLAKQNNPGTIPDIPN
>NC_019693.1|WP_015149876.1|4669007_4669193_-|hypothetical-protein
MMQVTATVRDMFINASLSQQISFHDWVLLNALPESNLSQEERRMIKRLMHSVRRGWFRVLS
>NC_019693.1|WP_015149875.1|4667337_4668948_+|uroporphyrinogen-III-C-methyltransferase
MTETGGIVYLVGAGPGDAAYLTVRSRQLLAEAEAVVYDALIDEQLLQLAPAGCQRIHVGKRGGQPSWQQADIDRLLVAQCQQGKRVVRLKSGDPFIFGRCTEEIQALKAARCPYEVIPGISSALAGPLLAGIPLTDPVMSHSFTVVTGHDCDRLDWETLTRTPTLVILMGTRQLDEILRQLLQHGKSPQTPIAIIRACGTSRQFVWTGTFADIRDRTRGESLSPAVIVIGEVVKLRDYLLPDSPSRRPLSPDSADSVSMSNYSSHAAKSSPHSASGLGGKTVLVTRSAGQSSTFTEMLTDVGATVIEMPALEIRPPSSWESLDSAIAQISEFDWLILTSANAVDYFCDRLLAKGKDTRILAGVKIAVVGKKTAATLQQRSLTADYIPPDFVADSLVEQFPEDVSGQKILFPRVETGGREVLVAEFTTQGAIVEEVAAYESGCPDAIAPEAWKALQQRRIDIVTFASSKTVRNFCQLLDRQSRSGDQPWHSLLNNVRIASIGPQTSKTCYELLGRVDVEAQEYTLDGLLQALQSGNG
>NC_019693.1|WP_015149874.1|4666366_4667182_-|glycosyltransferase-family-2-protein
MSTQQQTISLLCPTRGRPEQALRLALSVLNTASQPQRVELLFYVDNDDRKQSEYLEQFKTHKPKLDRFRRCGFLLGEAIGISKAWNELASRCEGNLLIMAADDQTYNDFGWDSRLDMETQKYPDEIFCMWFNEGHWQEKLCTFPIVSRKWCQTLGYFTTGLFECLYDDMWIWEIAKRVGRLHYIPDILTEHLHWGYGKAELDETYQHKQVDADKKLKPAVYRDMDLYCRTVPYRETDARRIAAVMQGQVFLYPVQLMVPGKSTIFDRRDKD
>NC_019693.1|WP_015149873.1|4665983_4666304_-|nucleotidyltransferase-domain-containing-protein
MQNTCSTLLPTLRTYFQTLYGKKLEQLILYGSQARGDAKPDSDIDILVILTDPVDAWNEIDRTSQFIADLCLEHTVVISTAFVSSHRFQQEKSPFFLNVHREGVPL
>NC_019693.1|WP_015149883.1|4679129_4680830_-|signal-transduction-histidine-kinase
MKMNLSTNQDVSLYDCALSAIAPPHPLQVSYPSFKGMVGGVFDLLIEQKIPATLWVKLPDWCNWQGDLNRYRNLLGSTNPVYILHPRQGEETAKTRDEEIEEEGGTGGTNPLYSRQRYSFFQQRSPAKQNSFDRHLHRHSPPYSAPLTCGIDENSLISDEGTIFMPTKTTLPLCSIQLMLNSKLNEEYFLIVLSPELSVAILASPAQSKGVESHSHRESHPNKTLVALYSLDQQTIQQVFDGLKVSVSKGRCQSCPISEENQYPIETSGRVCENLLANWDIAFGHMELSKPDPLLLGHLFSKQLQRLEQQGQELAGEGELAALQRQNQELLDALKFKDEFLNKIGQELRTPLTNMKTALSLLDSPKLKPAQRDRYSALLHQSCDRQNALIEGFLELVRLESEVDQAKMEGIRLGELVPGIVSTYQPIAQEKGVLLAYTLRSTLPPVVCTRDWIKKIVINLLQNAIKFTGSGGEVWVRSKQQGDYVQLEFRDTGTGIPPGEIPKIFEAFYRGRQAINDDIEGAGLGLTIVQQLLLHSGGSITVKSRVGRGSVFSILLPVYNESDGEW
>NC_019693.1|WP_015149884.1|4681450_4682944_-|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase
MKLKALLPSILLETLDKEALEIEVTGLSTNSHGCKPGDLFIGMPGTRVDGGDFWPSAIAAGAVAALVSPQAAQKHPPQSDAVVIPVADMTAACAQVAAAFYGEPGKKLNLIGITGTNGKTTTTHLVEFILQKVQKPTALLGTLYVRWPGFEQVAAHTTPFAVDLNHQLSDAVQAGCEFGVMEVSSHSLAQGRVQGLPFQVGIFTNLTQDHLDFHATMEDYFEAKAKLFSAEYLQGCAVVNIDDSYGQRLAERLSGDKLWGYSTHNSQADLWTSDIEYEPAGVKGMLHTPVGNAKFSLPLVGQYNVENMLAAVGAALHFGIPLAEIVAVLPEFPGVPGRMEQVLIKPDQDISAIVDYAHTPDSLENVLKATRPFISGKLICVFGCGGDRDRTKRPIMGKIAAELADVVVVTSDNPRTEDPEQILKDVAAGIPQSISARVIGDRAIAIRTAILEAKPGDGVVIAGKGHEDYQILGTEKIHFDDREQAREALNQRFAAVV
>NC_019693.1|WP_015149885.1|4683166_4683463_-|glutaredoxin-family-protein
MRLILYSKPDCHLCEGLQEKIEQIRDLKFELEVRDITTQAEWFAAYQYEIPVLCRVIDPDPDSENQAKEEPLPRPSPRASVQQVQQMLQQYFPKNDSQ
>NC_019693.1|WP_044197399.1|4684209_4684944_+|phosphoadenosine-phosphosulfate-reductase
MVNSVQAPTKSTTSLDLDELNQRFESSHPHEILAWCINNFPTGLVQSTAFGASGMVVMDLLYRELKSNPPVPVLFLDTLHHFAETLELVERSKQHYNLDLHIYKNPEASDRQEFAKHYGTALWHSNVEQFHYLTKVEPLKRGLEELNVVAWITGRRRDQSSSRAQMPIFERDNDGRIKVNPLANWTRKETWGYIMQHNVPYNSLHDQGYGSIGDEPLTTPVGAGEHERAGRWRGSAKSECGIHI
>NC_019693.1|WP_015149887.1|4685060_4686368_+|exonuclease-subunit-SbcD
MIKILHLSDIHIGSGFSHGRINPATGLNTRLEDFVSTLSRCIDRAIAEPVDLVLFGGDAFPDATPPPFVQEAFARQFHRLVEANIPTVLLVGNHDQHSQGQGGASLSIYRTLGVPGFIVGDRVTTHRIETAKGPVQIITLPWITRSTLMTRQQTEGISLSDVNQLLIDRLRVVLEGEVRKLDKTVPTVLLAHLMADRAELGAERFLAVGKGFTIPISLLIRPEFDYVALGHVHRHQNLNPTNNPPVIYPGSIERVDFSEQKEDKGYVMVELERGQVKWEFCPLVVRDFKTIKVDVSEAENPQEQILKAVGKQEIKDAVVRLIYQLRSHQIDLIDNTVIHAALSAAHNYTIQAELVSQLARPRVPELNAGAGIDPLSALQTYLDNREGLEDIKTDLLEAAEGLLAGDEQMWQFSSTAEDGEERKAIDDASVQLKLL
>NC_019693.1|WP_052315758.1|4686486_4687086_+|hypothetical-protein
MRIHKISVTNLFGIFNHSIPLNLDERITIIHGPNGFGKTILLRMLNGLFNFRYLELVTIPFTEFRVEFDEGTQLVVTQSIDKNPKAKKHPATLQLLNAKSSKSDKFQLIDVASDSKRFKQISQVIDSIIPEINRINYTTWLHLQTNEQLSFEDVIARFGQFFPEELGKIAPDPSWLIDVKKSEVLNVNKNLIRIAQIML
>NC_019693.1|WP_015149888.1|4687120_4688143_+|IS4-family-transposase
MTKHTFFQIVKDILKDLPKNDYPVLNSRLFVDCWLSYVMDNSLTSMRDLFKRLNNTGFDVHISTFSKASSHRDLKPFQKIYQKLNQLVQKGNHKKLHDKYSVCPIDSTIITLTSKLLWVLEYHQVKLFSSLNLATGSPEDNFINFGYDHDYKFGSKMMSSLPQDAVGVMDRGFAGLNFIEELVQENKYFVLRIKNNWKLEFEESSGLVKVGSSRDAKAYRVINFCDIETKTEFRLITNLPNEGDAAVSDDEIRDIYRLRWAVELLWKFLKMHLKLDKLITKNVNGITIQIYVSLIAYLILQLVSIPEQWGHTLLDKFRYLQSCMCQKISYVHWFEEIMFC
>NC_019693.1|WP_052315759.1|4688223_4689027_+|AAA-family-ATPase
MPVRLIEAQRLLNLSNVLRGRGYPRFPSSITSVAAYSSVAAYSEELAEHIQSKLAEYGELAQSLDRTFPARVVKTTAPSDLTADKIHTKLREIEEKRYRLIAAGLLNQDEDPDFQVDRSIDDTAKSILSVYVEDVENKLRVFEEFAQKIEILKRIINSRFCYKNISVNKEKGFIFQADDSKHLSPENLSSGEQHQLVMLYELLFKAKPNSLILIDEPELSLHVAWQAQFLKDLQEIAQLVNIDVLMATHSPDIISDRWDLTVELKGP
>NC_019693.1|WP_015149889.1|4689099_4690071_-|aldo/keto-reductase
MPTNLSLPIMGCGTWAWGNRLLWGYEPSMDAELQAVFNLCVENGVTLFDTGDSYGTGKLNGRSETLLGRFSQEYQGVNADKICIATKLAPYPWRLTRRSMVSAGEASARRLGRLDLVQMHWSTANYAPWQEWSLLDGLADLYDRGLVKGVGLSNYGPKRLERVYQKFSDRGVPIATLQVQYSLLSTYPVTTLGLKEVCDRLGIQLIAYSPLALGLLTGKYSEKGPFPPGIRGLLFRNILPKIQPLLDCLRAIASNRNKTMSQVAINWCICKGMIPIPGAKTVEQAQQNLGALGWSLDAGEIEELDQVAANSKKTMVQNNFQTT
>NC_019693.1|WP_156824072.1|4690251_4690467_+|hypothetical-protein
MLGYFMSHPELLEKLQQLSHDEKLEILQFLTTELAKEESLIALDNSAAYRSWSPYDYGDAAQKLMNLLAEE

Crispr_ID: NC_019693_45

• CRISPR_ID: NC_019693_45
• CRISPR_location: 4744682-4744776
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_45

Consensus_repeat	Method
AATTTAATGACGAAAAATCAGGGTTTCTTG	CRISPRCasFinder

spacers of NC_019693_45

>45.1|4744712|35|NC_019693|CRISPRCasFinder
GACAGGCGATCACTCTCGCGCCCCTACAAGAGGTA

CRISPR arrays and Neighbor proteins around NC_019693_45

CRISPR arrays

The CRISPR arrays of NC_019693_45

>merge|NC_019693|45|4744682-4744776|CRISPRCasFinder
AATTTAATGACGAAAAATCAGGGTTTCTTGGACAGGCGATCACTCTCGCGCCCCTACAAGAGGTAAATTTAATGACGAAAAATCAGGGTTTCTTG

>NC_019693|45|44|4744682-4744776|CRISPRCasFinder
AATTTAATGACGAAAAATCAGGGTTTCTTG	GACAGGCGATCACTCTCGCGCCCCTACAAGAGGTA
AATTTAATGACGAAAAATCAGGGTTTCTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_044197434.1|4753671_4754673_-|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|226229
NC_019693.1|WP_015149935.1|4755116_4755380_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_052315760.1|4759289_4759928_-|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_019693.1|WP_015149928.1|4742938_4743208_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149927.1|4741858_4742368_-|DUF1993-domain-containing-protein	unknown	unknown	gnl|CDD|370447
NC_019693.1|WP_015149923.1|4737492_4737867_-|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|378915
NC_019693.1|WP_015149925.1|4738315_4738843_-|hypothetical-protein	unknown	unknown	gnl|CDD|377670
NC_019693.1|WP_044197430.1|4749999_4751868_+|protein-kinase	unknown	unknown	gnl|CDD|238121
NC_019693.1|WP_015149938.1|4757781_4758321_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_019693.1|WP_015149937.1|4756863_4757664_+|TIGR03943-family-protein	unknown	unknown	gnl|CDD|274870
NC_019693.1|WP_015149931.1|4744962_4749195_-|NACHT-domain-containing-protein	unknown	unknown	gnl|CDD|238121
NC_019693.1|WP_015149929.1|4743800_4743998_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044195431.1|4755459_4756545_+|permease	unknown	unknown	gnl|CDD|281730
NC_019693.1|WP_015149939.1|4758395_4758941_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_019693.1|WP_044195425.1|4736618_4737161_+|GerMN-domain-containing-protein	unknown	unknown	unknown
NC_019693.1|WP_015149933.1|4751891_4753274_-|histidine-kinase	unknown	unknown	gnl|CDD|236901
NC_019693.1|WP_156823892.1|4743471_4743660_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823891.1|4737208_4737370_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149930.1|4744210_4744411_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156824075.1|4739681_4741370_-|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|378147

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_044197434.1|4753671_4754673_-|GGDEF-domain-containing-protein	gnl|CDD|226229	COG3706, PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms].	9.46898e-64
NC_019693.1|WP_052315760.1|4759289_4759928_-|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.14753e-21
NC_019693.1|WP_015149927.1|4741858_4742368_-|DUF1993-domain-containing-protein	gnl|CDD|370447	pfam09351, DUF1993, Domain of unknown function (DUF1993). This family of proteins are functionally uncharacterized.	4.48563e-52
NC_019693.1|WP_015149937.1|4756863_4757664_+|TIGR03943-family-protein	gnl|CDD|274870	TIGR03943, TIGR03943, TIGR03943 family protein. Members of this occur in gene pairs with members of pfam03773. The N-terminal region contains several predicted transmembrane helix regions while the few invariant residues (G, CxxD, and W) occur in the C-terminal region.	7.93157e-84
NC_019693.1|WP_015149923.1|4737492_4737867_-|nuclear-transport-factor-2-family-protein	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	2.95183e-08
NC_019693.1|WP_015149925.1|4738315_4738843_-|hypothetical-protein	gnl|CDD|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	0.000109633
NC_019693.1|WP_015149938.1|4757781_4758321_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.14274e-16
NC_019693.1|WP_015149931.1|4744962_4749195_-|NACHT-domain-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	7.19826e-109
NC_019693.1|WP_044195431.1|4755459_4756545_+|permease	gnl|CDD|281730	pfam03773, ArsP_1, Predicted permease. This family of integral membrane proteins are predicted to be permeases of unknown specificity.	1.22605e-58
NC_019693.1|WP_015149939.1|4758395_4758941_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.09395e-16
NC_019693.1|WP_015149933.1|4751891_4753274_-|histidine-kinase	gnl|CDD|236901	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS.	1.66052e-40
NC_019693.1|WP_044197430.1|4749999_4751868_+|protein-kinase	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	2.65265e-81
NC_019693.1|WP_156824075.1|4739681_4741370_-|DDE-type-integrase/transposase/recombinase	gnl|CDD|378147	pfam09299, Mu-transpos_C, Mu transposase, C-terminal. Members of this family are found in various prokaryotic integrases and transposases. They adopt a beta-barrel structure with Greek-key topology.	4.85367e-14

Protein sequences

>NC_019693.1|WP_015149930.1|4744210_4744411_-|hypothetical-protein
MLIQKIIQNLQNIPEEKLVEIYDLIHEKTATLTINEAEARTPGLLTGKLSDAFFEPLPAEELQRWE
>NC_019693.1|WP_015149929.1|4743800_4743998_-|hypothetical-protein
MNPTTLIQSGVAILIGASFGIVNVPGVLDSGKIVEVAVAAEPYPEADENGDYYIVNGGGWLIYAL
>NC_019693.1|WP_156823892.1|4743471_4743660_-|hypothetical-protein
MSPRNQSVCRCFSHGFGSYLISDSPVADGAEEAYLQSLANTFYKKRHLICQNYKRRHLIGQA
>NC_019693.1|WP_015149928.1|4742938_4743208_-|hypothetical-protein
MDNIKQQITQNIENWILKDEGIRTQVTKLAQGCSDTIELGKAMVTYFDENLPEIPEPFDELLALALGVADWYAIAQIFEEFLNSSEEEE
>NC_019693.1|WP_015149927.1|4741858_4742368_-|DUF1993-domain-containing-protein
MSHQNIDSIITVFQSRLTTLEHLLKLAQKHFGESEAFLDKRIATDMLPFGTQIAFTCNQPRNFALWSNGKPMNNLAPEVTSIAAAYEHIANTQELLSSIHTEDEKLNELVRIDSQDRYIEIFGHAYVNDFLIPNFYFHLVTAYDILRMAGVPIGKQDYMMHLVPLIQKA
>NC_019693.1|WP_156824075.1|4739681_4741370_-|DDE-type-integrase/transposase/recombinase
MDRSDSVEETNIIIRELSEEAQLRMEVIESLLEPCDRATYGEKLREGAKKLGKTVRTVQRLVKKYQSEGLAALSDTSRGDKGQHRIHPFWEDFILKTYAQGNKGGKRMSRKQVALRVEAKAMELGRDDYPSYRTVYRVLTPIIEQKEQKKTARSIGWHGSRLSLKTRAGQDLAVEYSNHVWQCDHTLVDLLLVDRHGVLIGRPWLTTVIDTYSRCIMGINLGFDAPSSQVVALALRHGILPKHYGPEYSLHCEWGTYGIPQHFYTDGGKDFRSNHLTQISVQLGFVCHLRDRPSEGGIVERPFGTLNTELFAALPGYTGSNVQQRSKEAEKEASLTLGELDRLLVRYICDRYNQSIDARLGDQSRFQRWEAGLLAAPPPLSERELDVCLMKEARRRIARGGYVNFQNLTYRGENLAGYGGEWVVLRYHPRDITKILIYLTQKGQEEFLARAYALDLEAEELSLDEAKANAQKIREAGKSVNNRSILHEVHDRQIFVDKKHSDRLKSRKARRQDEQKELRSPQKLVEQPEPEEVEADEILSASESETDVEVLDYDQLQEDWGL
>NC_019693.1|WP_015149925.1|4738315_4738843_-|hypothetical-protein
MNPKDIEPWLFQVEPFTEESLSYFLGRFRRANHLTPNGLGQRAGIGAVVTRWEKFYLSPFPTPEEWQALASVVGVEVDRLLEMLPPRGVTLKPKPIMLCGACYGEAPYHRIQWQFKENSGCVSEAPAKQARHPLRLLSKCTNCGTPFPIPALWHQGECLRCFLPFATMAKRQKSL
>NC_019693.1|WP_015149923.1|4737492_4737867_-|nuclear-transport-factor-2-family-protein
MTNNSIPEWMLQLFSNVDSKNTDGFVQFFTPDGYFRFGNNAPATGQAEVFQAVTGFFEMIDGIQHDFRQAYKAGDAEILEGYVTYTKTGGQVLDPIPFCCVFEMRGEKIFGYRIYVDAAPLFAA
>NC_019693.1|WP_156823891.1|4737208_4737370_+|hypothetical-protein
MELYERSLSCAASERKLTSDPDLRFFGEQTLNVEAKKRIASTFGVQCYTQSGC
>NC_019693.1|WP_044195425.1|4736618_4737161_+|GerMN-domain-containing-protein
MQEVFHSNSILKKYITQPFVGITLVILLSVTGCGTPPTTTDPGMPSSPSNGAVSPEIQQPQSVAMANVTIYEVDPQCQELLPQTVSVPSDRPIEAAVGEVIQNAGTVDFNIVGYRVTVDNTTGVATVDLRADPNSQRQFVSLSSCERFSLFGSLERTLTENPQWQIQSVEFTERGEPLDI
>NC_019693.1|WP_015149931.1|4744962_4749195_-|NACHT-domain-containing-protein
MVGIDEIVRAILAIARVATPVIINTARRNELVIKLLKKFQIDADHPPADFTGVYRYALVEYGIQNLDNFDVDQLQLVLELFRQNEIYQGFRKAFDRNDPYTLLSEAESYIDGFALGDKIRESHIDYQRELAKFSSIFMEIANRTRTPAEVLEFRKIEDLRYNTNQILERLENLNALEDLRQEIAKLTASDPDPILPAAGNQPRLNSAFARQLRNWLEALYDFESYEVQTPTYFEWIINIRARRGFDRIVVRGIEGEVTISDVNHLRESVEVQKADEGWLVAPRRISQAAVDIVENDEVLFCYTFDELIDEVADFSRYIDWLEGEVMQRDIERLYVPLACTKEELDPITHQRIAKSRYDERNGWIDRYINRWVDDPAKEHISILGEFGTGKTWFALHYAWETVKKYRAAKEEGLPRPRLPLVIPLRDYAKAVSVESLFSEFFFRQHEIGLPGYSAFEQLNRMGKLLLIFDGFDEMAAKVDRQQMINNFWELAKVVVPGSKVILTCRTEHFPEAQEGRALLNAELKASTANLIGATPQFEVLEIEKLNSTQIREVISKRATAATVEKVMRNAKLLDLAKRPVMIELILEALPEIESGKPIDLSRIYFYAVRRKMERDIKTERTFTSMADKLYFLCELSWEMLSSDRMSLNFREFPNRLRRLFSTVVQQQKDLDHWHYDMMAQTMLIRNAEGDYTPAHRSLLEFFVAYKFAVELGILAPDFAEFADLKQFPPPSELSQTFGKAPLTQAVLELLLPSVDPGETTKTRLLQLVQSTQGQCETEAGYLGGNAVTLLLKLDPNALDNSDLRDTVILGADFTSANLRNVNLAQANLKHCTFTTVFGTVLSAAFSPDGEWFATGDANGEIYLWQVEGKPLVLCQGHSAAVWSVAVTPDGKTLVSGSDDGTVKTWDVRTGNCLQTLPGHSHFVRAVAVTPDGKTIISGSNDRTLKLWDLETGHCHTTLYGHGSIIWSVAVTPDGQTIASGSADQTVKLWDVETGVCRKTLEGHTEWVLSVAITPDGQTLASGSAGGTVKLWDLTTGNCHTTLEEQSSSVWSLAVAADNRTLIGGSADGTVKVWDMTTGDCLHRLPEHNSRVGTVAIAPDGRTLVSGSDDETVKLWDIVRGECLTTLQGYASAVWSLALAPDGNTLASGSADRSVKLWDLTTGECLNTWQGHPSKVLSVAIPATGDYLTSISDDGTLHHWEMQTGEPLTTQWRPPSSGEVMALSPDGQTLACGSADCTVKLWDLQTEQGMTPLQRHTSRVVSLSFSSDSTILVSGTNDGTMNLWDFRTGECLKTLQGQGDYVWAVAVSPDGQTLASGREDGIVSLWDVETGDCLKTLEGHGSAVLSLVFHPEGKTLVSGSYDETIKVWELDSGDCVQAIVNKPYAGMDITGVRGLTEAQKATLKALGAIEQ
>NC_019693.1|WP_044197430.1|4749999_4751868_+|protein-kinase
MSYCPNPDCPNPINPDLTMFCRTCGTKLVLAQRYRLVKLIGMGGFGRTLLALDEFKPSKPQCVVKQFYPQSQQNAEKANQLFQQEAIRLEQLGKHSQIPELFAHFEQENRQYIVQEFIDGQNLTEELAEQGRFSESAIVSLLEDLLPVLDFVHKGKVIHRDIKPENIIRRRHDRKLVLVDFGAAKYATGTTLNQTGTTIGTKGYAAPEQTFGKAVFASDIYSLGVTCIHLLTTREPFEMYDAMESTFVWREYLGINKVSDRLATVLDKAIESSVRRRYQSAEEFIQGLKAAPSKGSRTITPQSRSPAPTPQRAIATVRVSTPPVTVSEIGSLVGHGAPVKAVAISANGQLLVSGSRSGVKWWQLHEGQELPTLRSSWPEEPFAGVSALAFSPDGRLLAAGSGGGAIALWDVTLRRILRLLKAPSGVKSVAFSPDGRLLAAGGTDGAIALWETASWRLFRPLMGHSAAVNSVAFSPDRRTLVSGSEDTSVVFWDVTTQADTQTGWGRSGAVNAIAISPCGRFLASGCANRTILLWELPSGQQIGTLTGHSTGVNSVAFSPDGATLASGSDDTSIVLWDVKTGQEKRTCWGRSGVVYAVAFTPDGNTLVSGTEDTTVKIWQLRG
>NC_019693.1|WP_015149933.1|4751891_4753274_-|histidine-kinase
MLATSVENLEQFVPVTPDRLVGKLTLDSTLADLTLFDFEIEVTCPGSELAKALAENPLLPGAILTESGKFVGTISRRRFLEHLSRPYGLELFSRRPLKSLHSFTKIEPLTFASYLPIGMAARQSLSRSPEFLYEPIVVEMEPNVYRLLDVHQLLIAQSQIYELTTQMLQEQTRSHTIQTEKMASLGRMVAGIAHEIKNPVNCIAGNMGFLANYCQDLLELVSVYEEEMETPSQKIVETIENIDLEFLRKDLPKLVQSLVVSSDRLTKIVGGLQNFSHLDETARKPADLHECLDSTLLILNNQIKYDIDLVKNYGDLPLVDCYSGQLSQVFMNLLGNAIDALLERKEKEADNLNKNPTWTPQLAIATELINREDESAVIIRIADNGMGIPPQIQQRIFDTFFTTKPVGKGTGLGLAISNEIVRDKHKGQINLNSQEGIGTEFEIILPLDRKPEIELRLDEE
>NC_019693.1|WP_044197434.1|4753671_4754673_-|GGDEF-domain-containing-protein
MKTLHLESTLSALSLYDYQVNAEVMGREVAETFNANPLLPGVILLGEGELLGMISRGRFFEQLSRPYGLELFYKRQIQILYRFTQIEYLRFKSSVTIVAAVQGVLSRSPDLLYEPIVVEIAPGIYRLLDVHQLLLAHAHIHELATQLLQNLYQQLEVANEELHRQATLDGLTQVANRRMFDRYLSQQWDRLTEEKKPLSLLLCDIDFFKGYNDTYGHQAGDSCLQQVARVLKECGNRREDLVARYGGEEFAVILPNTFADGAIAVADRIRKALATLQIPHENSQVCDRITLSIGIATVIPTKHDSLERLIASSDQALYRAKQQGRDCSICHEN
>NC_019693.1|WP_015149935.1|4755116_4755380_-|hypothetical-protein
MVYRVGSPFAFNPPRPGTGMNPEESLDAFEIGAQCKPPSPYYKVQGKTWGWRSPTSGLIPTPFFPGSSPTGAVGFPGSTPRDHQGNG
>NC_019693.1|WP_044195431.1|4755459_4756545_+|permease
MNQVHNAFTLFMSLLVEALPFLLLGVLLSSALLLFVDEKKLISSIPPNPVLGALIGSSIGFLFPVCECGNVPVARRLLMQGASPAVAIGFLLAAPTVNPIVIWSTWTAFRDQPELVVLRVVFSLGIATIIGSIFSLQKDLTPFVQPMVARAMNQSAKTKSCDPRPSKGLSSDSENSSPLLQSGTFLLGSPGSPQRLDATTMETVLLASKAGNLGGAGVALPGDRLFSQRLRLFVENVMVELRELGGILVFGSAIAAIIQVAAPRDLIISLGQGPVTSIIAMLVLGAVVSICSTVDAFFALSFASTFTTGSLLAFLVFGPMIDIKSIGLMMSIFKPKALVYLFLISAQLTFLLTLAYNLKFS
>NC_019693.1|WP_015149937.1|4756863_4757664_+|TIGR03943-family-protein
MAVQSPKLFRFSTWGPWIEVLAVFAWGVLLLKYWVSGELNILIHPNFFALTNGTGVFLILLACYKAAQLVHQQWRSRRVRNRGARTATPATDHITLFPPGWSASLLLVTAVLGFLISPRVFASDKAMMRDVNDFLPVTQSQPQAFRTARKPEERSLIDWVRTLTVYPEPDAYTGQQVNVQGFVIHLPDLPEEYFLISRFVITCCAADAYPVGLPVKLSQSRSAYPPDTWLEIQGEMSTEVLENRRQLTIVANSIQEIPEPRNPYEY
>NC_019693.1|WP_015149938.1|4757781_4758321_+|pentapeptide-repeat-containing-protein
MNPTLSLTPRELLARYQAGERNFAGIRFIEPNNDPEALCGADLSGIILRGAYLPGVKLREANLTGAKMMGVYMPDADLTLADLRKAELIGATLKRACLECADLSCTLLEGVNLIGANLDGTEISNSPLAYSVLCQTNFSKMWPSPPYFYTDIYCAGSLLWETTMPDGTFIAGAEYDLRY
>NC_019693.1|WP_015149939.1|4758395_4758941_+|pentapeptide-repeat-containing-protein
MTQNLLISLSELLSRYQAGERNFAGYVPPRSLRNLDLSNIIFSGANLEEASLIDSKLCGAQLVGTNFVGAFLIQTDLSGADLTGANLDHAHLWGVNLRGAKLIDANLTRAQFGLSSVESYSNLTSANLRGSILADVRLGWVQIDPGYPRQLDCTGALLWNTTLPDGIFVAGPTYLNSEVSK
>NC_019693.1|WP_052315760.1|4759289_4759928_-|pentapeptide-repeat-containing-protein
MGKKLGKTQPLPQSDGVGFVVLLLLRYKHFSRLQNVKNKTNNKYMMSMTIEDLLTNYENGKRNFVGIHFNVDGSRAKLKGADLRGINLMGAYLFHVYLVEANLADSCLIGANLSHAVLVKANLSHANLVNINLHRSNLHSADLSRCDLESANLSWARLQQTNLLYATLGRSNLAYANLTGAKNLNLYQADGVLLWNTILPDGSVEVGPKYSN

Crispr_ID: NC_019693_46

• CRISPR_ID: NC_019693_46
• CRISPR_location: 4756700-4756774
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_46

Consensus_repeat	Method
CAAGGGGAGGGGACCGGAAGTGAAG	CRISPRCasFinder

spacers of NC_019693_46

>46.1|4756725|25|NC_019693|CRISPRCasFinder
AACCCCACCCTAACCCTCCCCTTGG

CRISPR arrays and Neighbor proteins around NC_019693_46

CRISPR arrays

The CRISPR arrays of NC_019693_46

>merge|NC_019693|46|4756700-4756774|CRISPRCasFinder
CAAGGGGAGGGGACCGGAAGTGAAGAACCCCACCCTAACCCTCCCCTTGGCAAGGGGAGGGGACCGGAAGTGCAG

>NC_019693|46|45|4756700-4756774|CRISPRCasFinder
CAAGGGGAGGGGACCGGAAGTGAAG	AACCCCACCCTAACCCTCCCCTTGG
CAAGGGGAGGGGACCGGAAGTGCAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_044197442.1|4763394_4764327_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044197434.1|4753671_4754673_-|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|226229
NC_019693.1|WP_052315760.1|4759289_4759928_-|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_019693.1|WP_015149933.1|4751891_4753274_-|histidine-kinase	unknown	unknown	gnl|CDD|236901
NC_019693.1|WP_015149937.1|4756863_4757664_+|TIGR03943-family-protein	unknown	unknown	gnl|CDD|274870
NC_019693.1|WP_015149943.1|4761294_4762134_-|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl|CDD|234708
NC_019693.1|WP_015149941.1|4759931_4760261_-|DUF3082-domain-containing-protein	unknown	unknown	gnl|CDD|371449
NC_019693.1|WP_015149946.1|4764653_4766672_-|glycogen-debranching-protein	unknown	unknown	gnl|CDD|283786
NC_019693.1|WP_015149935.1|4755116_4755380_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149938.1|4757781_4758321_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_019693.1|WP_156823892.1|4743471_4743660_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149931.1|4744962_4749195_-|NACHT-domain-containing-protein	unknown	unknown	gnl|CDD|238121
NC_019693.1|WP_015149929.1|4743800_4743998_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149939.1|4758395_4758941_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_019693.1|WP_044195431.1|4755459_4756545_+|permease	unknown	unknown	gnl|CDD|281730
NC_019693.1|WP_044197430.1|4749999_4751868_+|protein-kinase	unknown	unknown	gnl|CDD|238121
NC_019693.1|WP_015149930.1|4744210_4744411_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015149944.1|4762396_4762906_+|rhodanese-like-domain-containing-protein	unknown	unknown	gnl|CDD|238089
NC_019693.1|WP_015149942.1|4760332_4761286_-|4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol-kinase	unknown	unknown	gnl|CDD|235049
NC_019693.1|WP_015149928.1|4742938_4743208_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_044197434.1|4753671_4754673_-|GGDEF-domain-containing-protein	gnl|CDD|226229	COG3706, PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms].	9.46898e-64
NC_019693.1|WP_052315760.1|4759289_4759928_-|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.14753e-21
NC_019693.1|WP_015149933.1|4751891_4753274_-|histidine-kinase	gnl|CDD|236901	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS.	1.66052e-40
NC_019693.1|WP_015149937.1|4756863_4757664_+|TIGR03943-family-protein	gnl|CDD|274870	TIGR03943, TIGR03943, TIGR03943 family protein. Members of this occur in gene pairs with members of pfam03773. The N-terminal region contains several predicted transmembrane helix regions while the few invariant residues (G, CxxD, and W) occur in the C-terminal region.	7.93157e-84
NC_019693.1|WP_015149943.1|4761294_4762134_-|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl|CDD|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	9.04653e-118
NC_019693.1|WP_015149941.1|4759931_4760261_-|DUF3082-domain-containing-protein	gnl|CDD|371449	pfam11282, DUF3082, Protein of unknown function (DUF3082). This family of proteins has no known function.	8.71724e-33
NC_019693.1|WP_015149946.1|4764653_4766672_-|glycogen-debranching-protein	gnl|CDD|283786	pfam06202, GDE_C, Amylo-alpha-1,6-glucosidase. This family includes human glycogen branching enzyme AGL. This enzyme contains a number of distinct catalytic activities. It has been shown for the yeast homolog GDB1 that mutations in this region disrupt the enzymes Amylo-alpha-1,6-glucosidase (EC:3.2.1.33).	8.53953e-156
NC_019693.1|WP_015149938.1|4757781_4758321_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.14274e-16
NC_019693.1|WP_015149931.1|4744962_4749195_-|NACHT-domain-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	7.19826e-109
NC_019693.1|WP_015149944.1|4762396_4762906_+|rhodanese-like-domain-containing-protein	gnl|CDD|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	7.11327e-19
NC_019693.1|WP_015149939.1|4758395_4758941_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.09395e-16
NC_019693.1|WP_044195431.1|4755459_4756545_+|permease	gnl|CDD|281730	pfam03773, ArsP_1, Predicted permease. This family of integral membrane proteins are predicted to be permeases of unknown specificity.	1.22605e-58
NC_019693.1|WP_044197430.1|4749999_4751868_+|protein-kinase	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	2.65265e-81
NC_019693.1|WP_015149942.1|4760332_4761286_-|4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol-kinase	gnl|CDD|235049	PRK02534, PRK02534, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional.	0

Protein sequences

>NC_019693.1|WP_044195431.1|4755459_4756545_+|permease
MNQVHNAFTLFMSLLVEALPFLLLGVLLSSALLLFVDEKKLISSIPPNPVLGALIGSSIGFLFPVCECGNVPVARRLLMQGASPAVAIGFLLAAPTVNPIVIWSTWTAFRDQPELVVLRVVFSLGIATIIGSIFSLQKDLTPFVQPMVARAMNQSAKTKSCDPRPSKGLSSDSENSSPLLQSGTFLLGSPGSPQRLDATTMETVLLASKAGNLGGAGVALPGDRLFSQRLRLFVENVMVELRELGGILVFGSAIAAIIQVAAPRDLIISLGQGPVTSIIAMLVLGAVVSICSTVDAFFALSFASTFTTGSLLAFLVFGPMIDIKSIGLMMSIFKPKALVYLFLISAQLTFLLTLAYNLKFS
>NC_019693.1|WP_015149935.1|4755116_4755380_-|hypothetical-protein
MVYRVGSPFAFNPPRPGTGMNPEESLDAFEIGAQCKPPSPYYKVQGKTWGWRSPTSGLIPTPFFPGSSPTGAVGFPGSTPRDHQGNG
>NC_019693.1|WP_044197434.1|4753671_4754673_-|GGDEF-domain-containing-protein
MKTLHLESTLSALSLYDYQVNAEVMGREVAETFNANPLLPGVILLGEGELLGMISRGRFFEQLSRPYGLELFYKRQIQILYRFTQIEYLRFKSSVTIVAAVQGVLSRSPDLLYEPIVVEIAPGIYRLLDVHQLLLAHAHIHELATQLLQNLYQQLEVANEELHRQATLDGLTQVANRRMFDRYLSQQWDRLTEEKKPLSLLLCDIDFFKGYNDTYGHQAGDSCLQQVARVLKECGNRREDLVARYGGEEFAVILPNTFADGAIAVADRIRKALATLQIPHENSQVCDRITLSIGIATVIPTKHDSLERLIASSDQALYRAKQQGRDCSICHEN
>NC_019693.1|WP_015149933.1|4751891_4753274_-|histidine-kinase
MLATSVENLEQFVPVTPDRLVGKLTLDSTLADLTLFDFEIEVTCPGSELAKALAENPLLPGAILTESGKFVGTISRRRFLEHLSRPYGLELFSRRPLKSLHSFTKIEPLTFASYLPIGMAARQSLSRSPEFLYEPIVVEMEPNVYRLLDVHQLLIAQSQIYELTTQMLQEQTRSHTIQTEKMASLGRMVAGIAHEIKNPVNCIAGNMGFLANYCQDLLELVSVYEEEMETPSQKIVETIENIDLEFLRKDLPKLVQSLVVSSDRLTKIVGGLQNFSHLDETARKPADLHECLDSTLLILNNQIKYDIDLVKNYGDLPLVDCYSGQLSQVFMNLLGNAIDALLERKEKEADNLNKNPTWTPQLAIATELINREDESAVIIRIADNGMGIPPQIQQRIFDTFFTTKPVGKGTGLGLAISNEIVRDKHKGQINLNSQEGIGTEFEIILPLDRKPEIELRLDEE
>NC_019693.1|WP_044197430.1|4749999_4751868_+|protein-kinase
MSYCPNPDCPNPINPDLTMFCRTCGTKLVLAQRYRLVKLIGMGGFGRTLLALDEFKPSKPQCVVKQFYPQSQQNAEKANQLFQQEAIRLEQLGKHSQIPELFAHFEQENRQYIVQEFIDGQNLTEELAEQGRFSESAIVSLLEDLLPVLDFVHKGKVIHRDIKPENIIRRRHDRKLVLVDFGAAKYATGTTLNQTGTTIGTKGYAAPEQTFGKAVFASDIYSLGVTCIHLLTTREPFEMYDAMESTFVWREYLGINKVSDRLATVLDKAIESSVRRRYQSAEEFIQGLKAAPSKGSRTITPQSRSPAPTPQRAIATVRVSTPPVTVSEIGSLVGHGAPVKAVAISANGQLLVSGSRSGVKWWQLHEGQELPTLRSSWPEEPFAGVSALAFSPDGRLLAAGSGGGAIALWDVTLRRILRLLKAPSGVKSVAFSPDGRLLAAGGTDGAIALWETASWRLFRPLMGHSAAVNSVAFSPDRRTLVSGSEDTSVVFWDVTTQADTQTGWGRSGAVNAIAISPCGRFLASGCANRTILLWELPSGQQIGTLTGHSTGVNSVAFSPDGATLASGSDDTSIVLWDVKTGQEKRTCWGRSGVVYAVAFTPDGNTLVSGTEDTTVKIWQLRG
>NC_019693.1|WP_015149931.1|4744962_4749195_-|NACHT-domain-containing-protein
MVGIDEIVRAILAIARVATPVIINTARRNELVIKLLKKFQIDADHPPADFTGVYRYALVEYGIQNLDNFDVDQLQLVLELFRQNEIYQGFRKAFDRNDPYTLLSEAESYIDGFALGDKIRESHIDYQRELAKFSSIFMEIANRTRTPAEVLEFRKIEDLRYNTNQILERLENLNALEDLRQEIAKLTASDPDPILPAAGNQPRLNSAFARQLRNWLEALYDFESYEVQTPTYFEWIINIRARRGFDRIVVRGIEGEVTISDVNHLRESVEVQKADEGWLVAPRRISQAAVDIVENDEVLFCYTFDELIDEVADFSRYIDWLEGEVMQRDIERLYVPLACTKEELDPITHQRIAKSRYDERNGWIDRYINRWVDDPAKEHISILGEFGTGKTWFALHYAWETVKKYRAAKEEGLPRPRLPLVIPLRDYAKAVSVESLFSEFFFRQHEIGLPGYSAFEQLNRMGKLLLIFDGFDEMAAKVDRQQMINNFWELAKVVVPGSKVILTCRTEHFPEAQEGRALLNAELKASTANLIGATPQFEVLEIEKLNSTQIREVISKRATAATVEKVMRNAKLLDLAKRPVMIELILEALPEIESGKPIDLSRIYFYAVRRKMERDIKTERTFTSMADKLYFLCELSWEMLSSDRMSLNFREFPNRLRRLFSTVVQQQKDLDHWHYDMMAQTMLIRNAEGDYTPAHRSLLEFFVAYKFAVELGILAPDFAEFADLKQFPPPSELSQTFGKAPLTQAVLELLLPSVDPGETTKTRLLQLVQSTQGQCETEAGYLGGNAVTLLLKLDPNALDNSDLRDTVILGADFTSANLRNVNLAQANLKHCTFTTVFGTVLSAAFSPDGEWFATGDANGEIYLWQVEGKPLVLCQGHSAAVWSVAVTPDGKTLVSGSDDGTVKTWDVRTGNCLQTLPGHSHFVRAVAVTPDGKTIISGSNDRTLKLWDLETGHCHTTLYGHGSIIWSVAVTPDGQTIASGSADQTVKLWDVETGVCRKTLEGHTEWVLSVAITPDGQTLASGSAGGTVKLWDLTTGNCHTTLEEQSSSVWSLAVAADNRTLIGGSADGTVKVWDMTTGDCLHRLPEHNSRVGTVAIAPDGRTLVSGSDDETVKLWDIVRGECLTTLQGYASAVWSLALAPDGNTLASGSADRSVKLWDLTTGECLNTWQGHPSKVLSVAIPATGDYLTSISDDGTLHHWEMQTGEPLTTQWRPPSSGEVMALSPDGQTLACGSADCTVKLWDLQTEQGMTPLQRHTSRVVSLSFSSDSTILVSGTNDGTMNLWDFRTGECLKTLQGQGDYVWAVAVSPDGQTLASGREDGIVSLWDVETGDCLKTLEGHGSAVLSLVFHPEGKTLVSGSYDETIKVWELDSGDCVQAIVNKPYAGMDITGVRGLTEAQKATLKALGAIEQ
>NC_019693.1|WP_015149930.1|4744210_4744411_-|hypothetical-protein
MLIQKIIQNLQNIPEEKLVEIYDLIHEKTATLTINEAEARTPGLLTGKLSDAFFEPLPAEELQRWE
>NC_019693.1|WP_015149929.1|4743800_4743998_-|hypothetical-protein
MNPTTLIQSGVAILIGASFGIVNVPGVLDSGKIVEVAVAAEPYPEADENGDYYIVNGGGWLIYAL
>NC_019693.1|WP_156823892.1|4743471_4743660_-|hypothetical-protein
MSPRNQSVCRCFSHGFGSYLISDSPVADGAEEAYLQSLANTFYKKRHLICQNYKRRHLIGQA
>NC_019693.1|WP_015149928.1|4742938_4743208_-|hypothetical-protein
MDNIKQQITQNIENWILKDEGIRTQVTKLAQGCSDTIELGKAMVTYFDENLPEIPEPFDELLALALGVADWYAIAQIFEEFLNSSEEEE
>NC_019693.1|WP_015149937.1|4756863_4757664_+|TIGR03943-family-protein
MAVQSPKLFRFSTWGPWIEVLAVFAWGVLLLKYWVSGELNILIHPNFFALTNGTGVFLILLACYKAAQLVHQQWRSRRVRNRGARTATPATDHITLFPPGWSASLLLVTAVLGFLISPRVFASDKAMMRDVNDFLPVTQSQPQAFRTARKPEERSLIDWVRTLTVYPEPDAYTGQQVNVQGFVIHLPDLPEEYFLISRFVITCCAADAYPVGLPVKLSQSRSAYPPDTWLEIQGEMSTEVLENRRQLTIVANSIQEIPEPRNPYEY
>NC_019693.1|WP_015149938.1|4757781_4758321_+|pentapeptide-repeat-containing-protein
MNPTLSLTPRELLARYQAGERNFAGIRFIEPNNDPEALCGADLSGIILRGAYLPGVKLREANLTGAKMMGVYMPDADLTLADLRKAELIGATLKRACLECADLSCTLLEGVNLIGANLDGTEISNSPLAYSVLCQTNFSKMWPSPPYFYTDIYCAGSLLWETTMPDGTFIAGAEYDLRY
>NC_019693.1|WP_015149939.1|4758395_4758941_+|pentapeptide-repeat-containing-protein
MTQNLLISLSELLSRYQAGERNFAGYVPPRSLRNLDLSNIIFSGANLEEASLIDSKLCGAQLVGTNFVGAFLIQTDLSGADLTGANLDHAHLWGVNLRGAKLIDANLTRAQFGLSSVESYSNLTSANLRGSILADVRLGWVQIDPGYPRQLDCTGALLWNTTLPDGIFVAGPTYLNSEVSK
>NC_019693.1|WP_052315760.1|4759289_4759928_-|pentapeptide-repeat-containing-protein
MGKKLGKTQPLPQSDGVGFVVLLLLRYKHFSRLQNVKNKTNNKYMMSMTIEDLLTNYENGKRNFVGIHFNVDGSRAKLKGADLRGINLMGAYLFHVYLVEANLADSCLIGANLSHAVLVKANLSHANLVNINLHRSNLHSADLSRCDLESANLSWARLQQTNLLYATLGRSNLAYANLTGAKNLNLYQADGVLLWNTILPDGSVEVGPKYSN
>NC_019693.1|WP_015149941.1|4759931_4760261_-|DUF3082-domain-containing-protein
MTNPTPTQPTPLSVTHEEPVQPTLMRCFMGSLISGGFAYACMMLTSAIASTFANKPIHSDNPIAVNISAAVRTLVTGVSTLATFVFAFAALGLFCLGLQLLFQKFTKKS
>NC_019693.1|WP_015149942.1|4760332_4761286_-|4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol-kinase
MRSYSLIAPAKINLYLEIIGDRPDGYHELSMVLQSIDLGDRVEIRANGTEDFRIHCQHPEVPCDRTNLAYRAAELLKTNYPEAFEQYGGADIFIDKQIPVAAGLAGGSSNAAAVLVGLEMLWDLGLTQPELHDLASQLGSDIPFCITGGTALATGRGNELEPLPDLEGLYVILAKYRSLGVSTAWAYQTYRQQFGSSYVRESPDLAARQKRVHSGPIVKAIALRDEMKVVECLHNDLEKVVLPEYPQVLKLRQTFEQCDVLGTLMSGSGPTVFALTDSREKAEQIRAQVQNTLGNPDLNFWIAKFINTGIQLAPGVH
>NC_019693.1|WP_015149943.1|4761294_4762134_-|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MPSPYPRKQFAQHWLQSDKALNEIVNAAALSPGDRILEIGPGTGILTRQLLSRAESVVAVEIDRNLSQKLAKKLGEIPNFLLLCADFLDLDLESVLTQTPEHFHHPNKVVANIPYNITGPILEKLLGTISQPPRMSYQSVVLLIQKEVAERINAAPGSRTYGALSVRVQYVAECEYICTVPAKAFYPAPKVDSAVVRLSPRPLALPADRPRWLETLVKVGFSSKRKMLRNNLKGLIDRDQLTQFLEQLNINPQVRAEDLSVSQWVALSNLLNLEHSVTP
>NC_019693.1|WP_015149944.1|4762396_4762906_+|rhodanese-like-domain-containing-protein
MANLADNIKQAKETLPNITPTPPDIKPQVTPGELKSRLEWGEPGLTIIDVRERESFNYERITGAMAMPMENLAETLSSSLEYKRDIYLYGDSDEQTKQAASQLRSGGFINVAEIKGGLPAWKAIGGPTEGIVSVEGPSGPSSVKKSESNVAARVGKQGDLEAKKSQQHR
>NC_019693.1|WP_044197442.1|4763394_4764327_-|hypothetical-protein
MSVQKIAVAVIHGMGSGDPDVDEGKLEQPKYFSRLSRQIIERFAQQLGISPEEAESRLVFEYIYWAPLLQPEQGELWEKVQGENLRFEWLRFFFINVLGDTIAYQVTSERDRSLYDRIHSRVAESLRNLAEKAGPTAPLCTVAHSLGSVIASNYFYDLQEFTRTQGSKVLMPEAVTNQMGNTPLERGETLSLFYSLGSPIALWSLHQKFDRPIQVPAKQLSNYHPDLVGEWVNFYDPNDIISYPLKPLSPEYEQVVTTDWPVNVGNVLTSWNPLSHVGYWSNDFITGAIAEALASTWKVVNPDYFPAIAQ
>NC_019693.1|WP_015149946.1|4764653_4766672_-|glycogen-debranching-protein
MLKSELGRELCGELATAESREWLVTNGTGSYASGTVAGLLTRRYHGLLMAALHPPLGHTLLFSKLDEVASYGSEDYPLFTNRWADGTVEPQGYLVLERFHLEGSIPVWSYGFGDALLEKRIWMQQGENTTYIYYTLRRSSLPVTLTMKGFATYRDRHHTTQENSRLMQVESVKSGLCITAFPGAVPFYLYAVGGAVSPAHQWHYGFDLAVEKSRGGDCLEDLLQVATIQGELQPGQSLAIAVSTDCNARLGVESAFQSRREWDQQLIKRALKGKGLKGKKGKNYQLSRKSPEWVRELVLAADRFIVDRPHLDNPDGKTIIAGYPWFGDWGRDMAIALPGLTLCTGRPQIGKLILQTFAQYVDQGMLPNRFPDHGETPDYNTVDATLWYFQAIRAYYQATKDKKLLKELWPVLREIIHWHQQGTRYQIQMDQADGLLYAGEPGVQLTWMDAKVGEWVVTPRQGKAVEVNALWYNALRTMAEFARKLGKPDEEYQKLGDRTLAGFDRFWNEGLGYCYDVIDTANGNDASLRPNQIFAVSLPDSPLPGKRQRSVVEVCGRSLLTSYGLRSLAATDPHYIGHYGGTVLERDGAYHQGTVWGWLIGPYISAYLRVTKDPKTAATFLRSLANHLLESCIGNLSEIFDGDAPMTPNGAFAQAWTVAEVLRVVAELKIEE

Crispr_ID: NC_019693_47

• CRISPR_ID: NC_019693_47
• CRISPR_location: 4870444-4870546
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: Cas14u_CAS-V

Consensus repeat of NC_019693_47

Consensus_repeat	Method
GGTGAGGTCATCTTCCTCACCAGAT	CRISPRCasFinder

spacers of NC_019693_47

>47.1|4870469|53|NC_019693|CRISPRCasFinder
ACGGTGACTACATCAACTCCAGCTTCCATTTCTATCTCGATCGCGTTCTCGGA

CRISPR arrays and Neighbor proteins around NC_019693_47

CRISPR arrays

The CRISPR arrays of NC_019693_47

>merge|NC_019693|47|4870444-4870546|CRISPRCasFinder
GGTGAGGTCATCTTCCTCACCAGATACGGTGACTACATCAACTCCAGCTTCCATTTCTATCTCGATCGCGTTCTCGGAGGTGAGGTCATCTTCTTCACCAGAT

>NC_019693|47|46|4870444-4870546|CRISPRCasFinder
GGTGAGGTCATCTTCCTCACCAGAT	ACGGTGACTACATCAACTCCAGCTTCCATTTCTATCTCGATCGCGTTCTCGGA
GGTGAGGTCATCTTCTTCACCAGAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015150028.1|4863179_4864220_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_019693.1|WP_015150033.1|4867659_4868250_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150029.1|4864649_4865243_+|IS607-family-transposase	unknown	unknown	gnl|CDD|225296
NC_019693.1|WP_015150027.1|4862000_4862588_-|thioredoxin-family-protein	unknown	unknown	gnl|CDD|239267
NC_019693.1|WP_015150032.1|4866718_4866919_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150041.1|4882447_4887472_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|368641
NC_019693.1|WP_015150034.1|4868468_4870007_-|apolipoprotein-N-acyltransferase	unknown	unknown	gnl|CDD|234721
NC_019693.1|WP_015150043.1|4889221_4892350_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|227328
NC_019693.1|WP_015150042.1|4887431_4889270_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl|CDD|225387
NC_019693.1|WP_071884340.1|4865130_4866327_+|transposase	Cas14u_CAS-V	-	gnl|CDD|223747
NC_019693.1|WP_015150045.1|4893508_4894948_-|hypothetical-protein	unknown	unknown	gnl|CDD|270916
NC_019693.1|WP_083896798.1|4892631_4893231_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150024.1|4857291_4857609_+|DUF3155-domain-containing-protein	unknown	unknown	gnl|CDD|314323
NC_019693.1|WP_156824076.1|4873463_4874387_+|histone-deacetylase	unknown	unknown	gnl|CDD|212518
NC_019693.1|WP_015150025.1|4858246_4858786_-|cofactor-assembly-of-complex-C-subunit-B	unknown	unknown	gnl|CDD|371864
NC_019693.1|WP_015150026.1|4859438_4861565_-|glycogen-debranching-protein-GlgX	unknown	unknown	gnl|CDD|131155
NC_019693.1|WP_015150037.1|4874451_4875609_-|DUF262-domain-containing-protein	unknown	unknown	gnl|CDD|377008
NC_019693.1|WP_015150040.1|4879307_4881986_+|ATP-binding-protein	unknown	unknown	gnl|CDD|379062
NC_019693.1|WP_015150039.1|4878224_4878812_-|HD-domain-containing-protein	unknown	unknown	gnl|CDD|379122
NC_019693.1|WP_015150038.1|4875980_4878047_-|Kef-type-K+-transport-system-membrane-protein	unknown	unknown	gnl|CDD|223551

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_071884340.1|4865130_4866327_+|transposase	Cas14u_CAS-V	-	4.8e-29	96.5	0.6

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015150028.1|4863179_4864220_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	2.69144e-33
NC_019693.1|WP_015150027.1|4862000_4862588_-|thioredoxin-family-protein	gnl|CDD|239267	cd02969, PRX_like1, Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic cysteine found in PRXs, which aligns to the second cysteine in the CXXC motif of TRX. In addition, these proteins do not contain the other two conserved residues of the catalytic triad of PRX. PRXs confer a protective antioxidant role in cells through their peroxidase activity in which hydrogen peroxide, peroxynitrate, and organic hydroperoxides are reduced and detoxified using reducing equivalents derived from either thioredoxin, glutathione, trypanothione and AhpF.	3.21666e-92
NC_019693.1|WP_015150029.1|4864649_4865243_+|IS607-family-transposase	gnl|CDD|225296	COG2452, COG2452, Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair].	4.92999e-51
NC_019693.1|WP_071884340.1|4865130_4866327_+|transposase	gnl|CDD|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.16035e-18
NC_019693.1|WP_015150041.1|4882447_4887472_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl|CDD|368641	pfam05860, Haemagg_act, haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins.	1.19869e-22
NC_019693.1|WP_015150034.1|4868468_4870007_-|apolipoprotein-N-acyltransferase	gnl|CDD|234721	PRK00302, lnt, apolipoprotein N-acyltransferase; Reviewed.	6.78248e-130
NC_019693.1|WP_015150043.1|4889221_4892350_+|CHAT-domain-containing-protein	gnl|CDD|227328	COG4995, COG4995, Uncharacterized protein conserved in bacteria [Function unknown].	4.67942e-100
NC_019693.1|WP_015150042.1|4887431_4889270_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl|CDD|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	1.57548e-114
NC_019693.1|WP_015150037.1|4874451_4875609_-|DUF262-domain-containing-protein	gnl|CDD|377008	pfam03235, DUF262, Protein of unknown function DUF262.	2.23214e-22
NC_019693.1|WP_015150045.1|4893508_4894948_-|hypothetical-protein	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.72493e-36
NC_019693.1|WP_015150024.1|4857291_4857609_+|DUF3155-domain-containing-protein	gnl|CDD|314323	pfam11352, DUF3155, Protein of unknown function (DUF3155). This family of proteins with unknown function appears to be restricted to Cyanobacteria.	1.92306e-49
NC_019693.1|WP_156824076.1|4873463_4874387_+|histone-deacetylase	gnl|CDD|212518	cd09992, HDAC_classII, Histone deacetylases and histone-like deacetylases, classII. Class II histone deacetylases are Zn-dependent enzymes that catalyze hydrolysis of N(6)-acetyl-lysine residues of histones (EC 3.5.1.98) and possibly other proteins to yield deacetylated histones/other proteins. This group includes animal HDAC4,5,6,7,8,9,10, fungal HOS3 and HDA1, plant HDA5 and HDA15 as well as other eukaryotes, archaeal and bacterial histone-like deacetylases. Eukaryotic deacetylases mostly use histones (H2, H3, H4) as substrates for deacetylation; however, non-histone substrates are known (for example, tubulin). Substrates for prokaryotic histone-like deacetylases are not known. Histone acetylation/deacetylation process is important for mediation of transcriptional regulation of many genes. Histone deacetylases usually act via association with DNA binding proteins to target specific chromatin regions. Interaction partners of class II deacetylases include 14-3-3 proteins, MEF2 family of transcriptional factors, CtBP, calmodulin (CaM), SMRT, N-CoR, BCL6, HP1alpha and SUMO. Histone deacetylases play a role in the regulation of cell cycle, cell differentiation and survival. Class II mammalian HDACs are differentially inhibited by structurally diverse compounds with known antitumor activities, thus presenting them as potential drug targets for human diseases resulting from aberrant acetylation.	2.04405e-138
NC_019693.1|WP_015150025.1|4858246_4858786_-|cofactor-assembly-of-complex-C-subunit-B	gnl|CDD|371864	pfam12046, CCB1, Cofactor assembly of complex C subunit B. Cofactor maturation pathways such as the CCB system (system IV) for cytochrome c-heme attachment are conserved in all organisms performing oxygenic photosynthesis. The CCB system consists of four protein, CCB1-4. The four CCBs are well conserved between green algae and plants.	9.08751e-94
NC_019693.1|WP_015150026.1|4859438_4861565_-|glycogen-debranching-protein-GlgX	gnl|CDD|131155	TIGR02100, Glycogen_operon_protein_GlgX_homolog, glycogen debranching enzyme GlgX. This family consists of the GlgX protein from the E. coli glycogen operon and probable equivalogs from other prokaryotic species. GlgX is not required for glycogen biosynthesis, but instead acts as a debranching enzyme for glycogen catabolism. This model distinguishes GlgX from pullanases and other related proteins that also operate on alpha-1,6-glycosidic linkages. In the wide band between the trusted and noise cutoffs are functionally similar enzymes, mostly from plants, that act similarly but usually are termed isoamylase. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NC_019693.1|WP_015150040.1|4879307_4881986_+|ATP-binding-protein	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	0.00294984
NC_019693.1|WP_015150039.1|4878224_4878812_-|HD-domain-containing-protein	gnl|CDD|379122	pfam13328, HD_4, HD domain. HD domains are metal dependent phosphohydrolases.	6.01566e-30
NC_019693.1|WP_015150038.1|4875980_4878047_-|Kef-type-K+-transport-system-membrane-protein	gnl|CDD|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	2.5402e-58

Protein sequences

>NC_019693.1|WP_015150034.1|4868468_4870007_-|apolipoprotein-N-acyltransferase
MGLTPAPFNAWPLAWIALVPLWILLVKPGEKPSETQRIWQWKFLGLPLLWGVGYHGIALFWITGIHPMTWLGVPWLASLAIACFCWTFITLWGAALVTLWAILLRAITRRFTPVSGHPPSPWVRVAIATAVWCSLEAIWSAGNLWWTALAYTQSHQNLIILHLGQLSGPTTITGAIVIVNGLIAEAILSFNSARNSPNRTRELLLASPIILFLILHGIGFALYNRPLNQSPETALTVGIIQGNIPNEIKFDSQGWRRALEGYTTGYQQLAEAGVDGILIPETAFPYLWTDENIRYSSFYQTILDYNATAWVGTFGSREGNFTNSLVTVTPDGETFSRYDKTKLVPLGEYIPFEEIFGKIVSRLSPLEARLVAGKPDQVFDTPFGRAIAGICYDSAFSKLFRRQAAAGGEFILSASNDAHYTATMMEQHHAQDVMRAIETDRWAVRATNTGFSAIVNPQGKTLWISEQNTYQIHSDTIYRRQTQTLYVRWGDWLLFGFWGLAAIACGVGWRRG
>NC_019693.1|WP_015150033.1|4867659_4868250_-|hypothetical-protein
MSSADPIKIILKLVKIFERLAIPYVTESGLARALKTDRQLPSFIALIVDLRRDKVAGLFEAIEPNFKVTEAAIREAIRAQSGFTLVHKETNIAVNLLLLKDESFWQSLFSRRKSITVQLNPERSLWIPSLEDIFLEKLIEYRDSDRNGDQLWRDLVWMLKVQNEDLDFEYLREWAIALHTVDIYDRALGEAGFDLL
>NC_019693.1|WP_015150032.1|4866718_4866919_-|hypothetical-protein
MVIQGNFYKLTISEIFCQIWRSGKITYLERWGLMSALLKDSLTPDEIDAINRLLHAVRRGWLRVEE
>NC_019693.1|WP_071884340.1|4865130_4866327_+|transposase
MRTFSPSSTALAPDYTDCVNTKLRSKKIQIYPSPELNKVWRKWLAACRYCYNQAIALQKSGKRLSKLKLRNEVMQSDLPAWVKETPCHIRQNAIFDAHLAFSASSDARFRSCRDSSQAIKFNDANFSSGSWYPRLTKGLTFRVSEPIPKTCDQGTQLVFTKGRWFAVFPEPVAFIPTEATGVIALDPGVRTFITGFDGSRFLEFGSGDIGRITRLCQHLDDLMGRIAKEPNRSKRRRMKQAAQRMRTKIRNLVDEAHKQIAHYLTRNYSVIFLPTFETSNMVAKAKRKIRSKTARAMLTWAHYRFKLTLKHQAEITGTTVVDVTEEYTSKTCTHCGHVHSKLGGSKVFRCPECGVTLPRDWNGAFGIFLKALRDTASVTLTGNSAIVALSGNNRKNVA
>NC_019693.1|WP_015150029.1|4864649_4865243_+|IS607-family-transposase
MARYVKPKEAAQILGVHERTLRRWDENGSIETIRTPAGQRRYNVESYTAFSGSDKRKVVIYARVSSRAQQSDLNRQVAALSNLYPEAEVVSEIGGGLNFKRKKMLALLGQVLSGDVRMVVVAHKDRLARFGFDLFRWLCEQNRCELLVLNETSLSPEREMVEDILAILHCFSSRLYGLRKYKTQVKEDPDLPQPRAK
>NC_019693.1|WP_015150028.1|4863179_4864220_+|pentapeptide-repeat-containing-protein
MTADLLNAPKFSFSKEELLQQYAGGNRDFNRLSLAKADLSEANLSGVYLGGASLTKANLSGANLSRANLSGASLSGANLTGANLTGANLAGAHLNWADLSGANLSGANLANADVSGANLSGANLSGAKLNQTYLIGTNLKSVDLREANLSLASLNKADLTKANLRQADLTGAKLKQSNLNLADLTHANLTGANLKQANLSQAHLNWANLTKADLREANLCGANLSKANLSQTDLTEVCLKDAQLSGINFSGANLTGVDLSNKLLTGANLSGAELSLANLSGAYLIQTNLREANLSEANLMGSHLMDADLTKANLSGANLSQANVVNVNLRGANLKGVIQPNGKARS
>NC_019693.1|WP_015150027.1|4862000_4862588_-|thioredoxin-family-protein
MSLTPSTMLALGTPAPDFQLPDVVTHKMISLETFGDKTALVVMFICQHCPFVKHIQEELANIGRDYHDRSVGIVAISSNSVETHPQDAPEHLKAMALTLGFSFPYCYDETQQVATAYTAACTPDFFVFDRSRRLVYRGQLDDSRPGNHQPVTGKDLRSAIDAVLAGDSIPEDQKPSIGCNIKWKPGHEPAYYGAW
>NC_019693.1|WP_015150026.1|4859438_4861565_-|glycogen-debranching-protein-GlgX
MHLEVWPGKVYPLGSYWDGKGTNFALFSENATAVELCLFDKDGKEQQVSITEVDNHVWHGYIPGISPGQRYGYRVHGPYDPGAGHRFNPNKLLIDPYAKAIEGDVINGPELSGYNWEDPEEDLSFSETDSAHLIPKSIVIDESFDWEGDQLLQTPFHETIIYETHVKGFTKLQPNIPEEIRGTYSGLAHPAVISHLQTLGITAVELMPVHHFLAYPGHLADKELKNYWGYDSINFFAPYSGYSSATVPGEQVQEFKEMVKALHKAGIEVILDVVYNHTGEGNHLGPTVSMRGVDNACYYRLVDDNLRYNMDFTGCGNSLNVRHPQILKLIMDSLRYWVLEMHVDGFRFDLASALARELYDVNNLGSFFNIIHQDPVLSDVKLIAEPWDVGPGGYQVGNFPLLWSEWNGRYRDTVRDFWRGEDRTLGEFAYRFTGSSDLYETTGRSPYASINFITAHDGFPLYDLVSYNEKHNEANEENNCDGESHNRSWNCGAEGDTDDPQVLALRERQKRNFLVTLMLSQGIPMLLAGDEMERSQGGNNNAYCQDSEISWLNWEFPEEKAQLLDFTRQLIYFRRKHPVFQRRKWFQGRPIYGKTVNDIAWFNPDGSEMEDEEWGVGFAKAIAVFLNGQEIPRRNRYGQRVIDESFIVFFNAHWESIEFKLPEGLNEQQWVALIDTKEPSFLEDGPTYTGDKAVPVFGQSVLVLRRAE
>NC_019693.1|WP_015150025.1|4858246_4858786_-|cofactor-assembly-of-complex-C-subunit-B
MDTTTLSSTFFLTLLMTIGLFFFIRASVKDRTEEMQWVTEQPEESILPELQGYFDRRAYRVKAVDGERNQVTFEGYVRPSWFLAIFLTLLAAVGMFCLALILSMVIPTGGNLFLGLILLSPVAGWFYWQNSGRMEQVSLQVKSLESSGDNPTQNRITVTGHRDELAVLKQTLGPQYRQG
>NC_019693.1|WP_015150024.1|4857291_4857609_+|DUF3155-domain-containing-protein
MARRRKRKSRRRQEGRRILEHVPQYSIESGEDKPVTAARKFIKAEGIVPPALLLVKRNEHTTDRYFWAEKGLFGAQYVEENHFLFPSLKFFESKAEIPPVALSVR
>NC_019693.1|WP_156824076.1|4873463_4874387_+|histone-deacetylase
MFSVIYSEEFLDHDTGRSHPERPARLTAIVEALKALPWASRLSWHLPTPGHQGSVLSAIQRVHTPRHIHEIEILAECGGGRLDIDTPVSRYSYEVALLAVSAWLDGVDRVVETGEPAFVLARPPGHHAESNRGMGFCLFSNAAIAATHALEKHGLQRVAILDWDVHHGNGTQEIVEKNPQIAYCSLHQYPCYPGTGAADETGPYDNILNLPVPAGSTLAEYQVLFESKVMPFLNEFQPDLLLVSAGYDANAADPLARIDLQPEDYGILTDYCLQLTRRIVFGLEGGYHLDALSKSVIATIARCLELS
>NC_019693.1|WP_015150037.1|4874451_4875609_-|DUF262-domain-containing-protein
MLEDGLGTQVEDSQELLEDQFEEEDEEELEEELTIPVKDRKLVTHPYDFVIRSLKAQIDDQTLVLADKFQRRQVWDQTKCSRLIESLLLNVPIPVCYFAELDDGSYSVIDGQQRLTAIYRFLNNEFPLRALKILPDINRKQFQDLEVSYQRLLLSRTIRCIVILKESHPDIKFDVFERLNTGFVPLNAQEIRNSVYRGKLNDLILELSEDEVFQKTRRVLSIDKRMQDCEMILRFFAFFFDPIAYRGTLSKFLDQYLEQGIHFDDETIEHHREIFRKTIDDVFAVFDYGAFRRYTPDTGWEKSINRAIYDVIMLSFAYVDSEDIRSSKTEIIEALKKVCQDPEFSESITSSTKNRDRIQTRIDKWRDAMTEIGLDVPKIKIGKDS
>NC_019693.1|WP_015150038.1|4875980_4878047_-|Kef-type-K+-transport-system-membrane-protein
MELALGFLKNEPIFAFAVLLAVILVVPIFFERLQLPGLIGLLAAGVAFGPNGLQLLQPQSETMKLLSDIGVVYLMFVAGLEMDMTEFQKVKNRAIGFGSLTFIFPLIAGTIIARFFGFSWNASILIGSLLSSHTPLGYPILSRLGLMGNEAVMVTIGGTIFTNIPALLVLAVCVSVHAGSFSLVNLAIMLVLLTLYTGIVLFGFDWAGREFFRRSGDEEGNQFLFVLLAVFLAAVGAQIIGVEKIVGAFLAGMAVNGAMGSGPVKEKVVFVGSVLFIPIFMVNLGLLIDLPAFIETLTSFWLTLAIISGLLISKLVAALGTQLLYRYTRAETLAIWSLSIPQVAATLAATIVGYNTLNPLGERLLSEEVLNTVIVMMLVTATLGPFLTARAAASLTPPTTNLDTVKTPFDEENQPNGPFTVIVPVYNPETEKNLVEMAALLVRREEGRIVPLSIARVMAQMEASAVDAALIRSENLVAAAVQLSQEFGVKAEPAVRIDDDIAQGIAHASREQKASLIVMGWGETTTLRARLFGNVIDRLLWTAHCPVAVTRLRGSPVQMKRILVSVDNLVARAVFSVRFAYSLAQMNGGQVTLFHVCDRRTPEEVNARIQAQLSALITELAPSDPAQIQIVIAPNDDIPGAILNEAIGYDLVILQATRRRTMSGLEMDDVTTTVIQELSCSLVMLGSS
>NC_019693.1|WP_015150039.1|4878224_4878812_-|HD-domain-containing-protein
MLSNRFNQALTFAAELHAQQQRKGSGVPYIAHLLGVTSIALEYGANEDQAIAALLHDAIEDQGGAATGAEIRRRFGDTVATIVEACTDADSTPKPPWRERKELYLSHLPTADPLVLLVSASDKLHNSRSILQDYRAMGESVWDRFKGGKTGTLWYYRALVEAFRPTAVNPWLFAELERTVMAIEQLALDPSEITG
>NC_019693.1|WP_015150040.1|4879307_4881986_+|ATP-binding-protein
MEQQQPIDVAAYNERSLNTLSRAIALSAEQFAIILVRCNYRHLQTEMLQRLRERFPVSVAEIHLPPLSTTLFGKMIEEFGELPSLPGVMVLGLESAVAIDELLISIDLVRDEFRKQFPFPLILWVTDDLLHRITQFAPNFKSWAGPSIKFEIPIPKLIQRLRQTAENLFNCILEAGADQLQVGAAIELLTHTHRQEIACAIKDIERAGESLDPYLQACLDFVRGWNAYSHDELATAREFYQRSLAFWEKAVPTVSASETPPEENSTPYLERYGCLLFYLGACWHREALLHRGTAQAAYRQARDYFQQCVAIYQQADRPDLMAKFINALGEVLQKLRDRDGLEEVASIATQLHQQYPDPIAEAQDCGYWGEVALWNSQWEIAKQSALNALQILEFSRTTALTPEKRSFLEWSAQYHRGWYLLLLGRARSALSESTQAIATLEEAKSEAQPECNPRLYSEILRELRSLYFNRGDRLTAFALKQELYALEHQYGFRAFIGAQPLQPQLHPLNPTQLLHLGIGDRPFPQKRYFGSSLTGREAEIKCAITRIGRPDYKLTLIHGPAGVGKSSLLSAQLAPALHQKQIGLHLALPLVISIQGDWFPGAVEVFNRAFAQMGLPIVDITEEQNRIPILHNLCDRLGENGDRNILTALLFDVDADLFDNAHESHRHLFYEFLHDCLNVPFVKAVVCLRTEHLADLLENESLRSLEFINRETRETLCYHLPDLSLDTAHRAVMTLTEQAEFPLEPELIQQLVRDLAQSTIAEVRGLMLQLAGTQLEAEQITTLSAYQDYGGKAALLRRGIREAISDCGVENTQIARSALQALAKTTPDCEQSPTMPYPCHKTLEELRTEIGSSPETLQIILEILVQSGLLFRLYDTPVPRYQLVDQEICRIV
>NC_019693.1|WP_015150041.1|4882447_4887472_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MKQVLLFFGLAANLTLWGLATPLLTLGQIVPDQTLPVNSIVTPEGQTHVITGGTSVNGTLFHSFEQFSVLTGHSAIFNNEAQIRNILTRITGGTISEIDGLLRANGAANLFLLNPNGIIFGANARLDIGGSFFASTGSEFVFADGRTYSATTPNAPPLITVDVPLGVQFGPSPGAIVNRSQVAIPVDNNQALPVGLQVPPGQSLMLLGGNVVLEGGLLTAPAGQIAIASMGENAQVTLNPTPRGIVVGNDGGQRFQDIRLSGGAIASTSAAVGGDIQLQGRQVSVQDGSVISTTSFGPGNAGNLTISATESVEVIGNSNKLEFIENILLPAGGFDPGIIRNGGLFALGLGEGAAGNIVIETGEFRANNGAIVTTTTTGNGVGGNLLVNATNSVILNNAGLLTGTAGTQDAGSLEINTGTLNLADGAIVATPSLSSGRGGDLTVNASIVELSGSSQETYQLPAPIFNRPSPLPSSLFTQALGTGNSGNLEINTQQLRLSGSAVISTSTLNVGTGGNLTINADTIDLNGIPSLGRLSILEQIVAASADPRAVDATLLQNGLFAVSFGPGNAGQLNINTRELNARNGATIAASAFQEGAGGNLTLTTPAEGSVNLSTGGILTGTVGIGDAGKLEINTGTLNLTNGAIVATPSLSPGRGGDLTVNASIVELSGSSLDIYQLPPPIFNTPSPIPSSLFTQALGTGNSGNLEINTQQLRLSESAAISTSTLNVGTGGNLTINADQIDLNGIPSLGKLGILEQIVDASKDPTAIDATLLQNGLFAVSFGPGNAGQLNINTRELNARNGATIAASAFQEGAGGNLTLTTPAEGAVNLSTGGILTGTVGIGDAGKLEINTGTLNLTNGAIVATPSLSPGRGGDLTVNASVVELQGISPETYELDQIFNTASPIPSSLFTQALGTGDSGNLEVNTQQLRLSGEAAISTSTLNVGTGGNLTINADRIDLNGIPSLGKISILEQFFGASANLSAIDASLLRNGLFAVSFGPGNAGELKINTGDLRVTNGSIIAASAFQSGTGGNLTITTPPTGGVNLDNGGLLTGTVGTGRAGNLQVQAGQLQLQQGGIISTSTVGPGLGGDLTVNANNIQLSGISQDGYNLPIFVEGSGPIPSSLLTLTIGVDPANPSGKAGNLTINTQRLLVEDNAAISTSTLGAAGDAGDLTVTANSQVQLRGIGPLVKPLTEIFNTTFNIANVRNGLFTSSLGSGKPGNITIQTRELLSENGSLISASSLSPSQGIEGLDGTENTAGTLTIRTSGGLVRLNDSGLLTGTVNQQDSGTLTLDTGQLVVENGSVVATTTLTQGDGGRLQVNADSVVLRGFSNVLIEGIPNVVPSGLFTLTFGTGRAGELEVNTANFTAENGGLAASSTFGRGEGGNLTLNAANQVKLSGGIPQDGQFPSGLRADVLDDLPPFAANLPLADQPENLGSGTPGNLTLNGGIILMQDQAAVQVSAGSVGDGGNLTVNAGVLALRSQSTMAADAGQGTGGAVEINTRQGIFAVDRANQITATSELGTQFSGRVDFNTPDVEAAQGLANLPENPIDPEDRVRSPLCSPAGETTAGEFIITGRSGLPQTPYEAIESDGVRVELVSPADSVPNRSGAPPVSSPVEQSGAILPPPAKGLVVNAQGDVMLTATTPNGLMSGTLWFTAECDRVRETTNSDSSSR
>NC_019693.1|WP_015150042.1|4887431_4889270_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MYEKQQIQTQVRGRWGLSVLPSQGGLRPQGNLLWVVLFGCLGIIGPGSLPRGLAQEGIPPASLPNPILPPTQEPQAPSLLPQNPDPLEIFPASPIPREEIPPVAEPTLVVERFEFVGNTLFTEAELAAVTAAYTNRPITFSELEAAANQVTELYLTQGYITSGGYVPSNQRIASGGGPVTIRIVEGRLEEEIQVVGTERLRSSYIRSRLVDPDEPLDLKRLEEQVRLLQSDPMIEQVSAQLSAGTQPGMSALRIQVSEASPWLGSQVGVDNSRNPSVGSFRQQGQVNYANLLGRGDRLSASYGRTDGSTDWDVSYGVPVNRSNGTLSFRYSNTNSDIIESPFDALEIESSSRNYELSFRQPALRRASKEKIQEFALGVTAARRESSTTLLGEGFPISPGASRDGETRISVLRVFQEFSERRSQQVWAARSQFSLGVGAFDATVNDRNPDSQFLAWRGQLLYLRRLNDSVGPILGGATMLLRSDLQLTNDGLLSLERFGLGGGQSVRGYRQDALLTDNGAFASAEVRLPILEVSQVRGILEVAPFVDLGMGWNHQGEKLDPNTLVGVGLGLRWQMGDRLTARMDYGVPLVKVDSGDRTWQENGLYFSVQYNPF
>NC_019693.1|WP_015150043.1|4889221_4892350_+|CHAT-domain-containing-protein
MARKWSVFFGAVQSVLKWRVRGQRRTLAIALCAALGWIGALSLPALTADSPNSGPVSVVEIRGAGEMAIALVERGQRLYNQGNFPEAVGVWQEAVAAYRTAGDWLNEAMALSNLSLTYQKLGEWNRAQEAIGQSLQRLPDPAVSNAGPDGVRILAQSLDIYGKLQLERGNPGDAIATWKRTATLYQQLRNPDQQRQSLINQAQALQVLGLYSRACDTLLQGFGETPNCQILLEEPPGDSQRTKSAQRLISRLSAQPANLITANGLRRLGDILRPLGRLHLSEDLLLLSQNMAQQLGSGDDVAAAWLSLGNTALAIGNQERDKDTPETIVLVPVQIDEITPMEKALQPYQKSLNYYQKIVNNYPGSRMALEAEINHLNLLIDIKNWWNVETQKILRAQNYRDQLNQDFLEKTSQLADDITELVNQNWPLTSNLINSRINFADNLLNGLKNEKFLPLAETILNQAVQDGKTIGNSRIQSYALGSLGSLYEQQEREAQETVRRQSGLDLAKDYTEQALALLNLYQSNNSGDRSITYADDRDLGYRWEWQLGRILEAQGNTREAIQVYDQAFEKLKSLRSDLGAINRDVQFYFRDQVEPFYREYAALLLTPEQPSQTDLEKTIEIFEALQLAEIDNLFQDPCSEIQQQQSRVDFLQAHASSNSAILYTMVLEASHSAKAVNPNSESVQIHLLLQRPQGIDYARSSLEKNKLATSINNFNKRFYVEYTRYLSENRSPENERERLNESKPEILEMLSQYYDWMIRPLEAQLKAVQTVVFVLDTPFQNIPVAALYDGQQYLIENKSVAFIPSWQLMNPNPLEVGQGLKVLAGGLSQGLCLNGERDCTPEQRQVTELPSVEIELDNIPTRVKLLNAQFTPENLQRELNRFRGHVVHLATHGQFSSNPEKTVIETFTRAINLKELEKLLQDKNTSTASQIKLLVLSACDAAQGDPRAVLGLAGVALRSGVSSAIAPLWLVKDSATAPLMIEFYRLLQQEQTNKAEALRQAQLALLQNRFPKLPDDYRFPKLPDDYSHPAYWAPYVLVGNWL
>NC_019693.1|WP_083896798.1|4892631_4893231_+|hypothetical-protein
MIQNIAVSEIWSFQECRTMKFKTLSLGLSMMMAAIGLSAPSAQSTSNLSLTYSCESRENGLSLIARLSAEGRSIEEREVFNWSRLPSTANPNQICQRVQDKLQQYASKQGIHDIYGFAVYEINGKPSVCLDQQATDQCTQVLFNSQQINQPDASTPEMVAILNNILSAQVRGNENQPTDPTRTYQSGSFHVPLWRILWN
>NC_019693.1|WP_015150045.1|4893508_4894948_-|hypothetical-protein
MSSDNGYYLNSLIGGKTPFRQTYLADNQPGVLTPEYIIKKIVPHPHPPRSFEEAKHLFRQEADRLYKLGKHPQIPAQLDEFDRDGVFYLVYERIYGESLAHELKDGKPWNEARVIVLIQEILEILKFFHTVGGPHLDINPHSFIRRRSDGKLVLIDFGAVRCHELSPMQWGTPGYMPPDTARETPGFHSDIYAVGSIAIQALTGVQPTQLQEGNSSFRWRNLAQVSDSLAATLDKMVNPYFRNRYDSVDEVLRDLKKNQLFSQFFRHLNLSQLSVYLKLPPKFLSIVAILFLVALSTPIFTRAYRNLQAYLLIQRGNEFNHLQDYDQAISAAEQALKYRSDFVAQAMLLKAYAMGQKNSQNTQERYKLCSAAEALRENYAAAWNCLGNIAFLQGQFELAIDYFDQVIQVYKDPNNPWYNEPREEIWAVWNKADILVKQTKYSDAHGLLTEFLNNKQGNIPGDLREQTNRKIKEIEALMP

Crispr_ID: NC_019693_48

• CRISPR_ID: NC_019693_48
• CRISPR_location: 4914840-4914972
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_019693_48

Consensus_repeat	Method
TGGCGCAGGATTGTTGACTGGCGCAGGA	CRISPRCasFinder

spacers of NC_019693_48

>48.1|4914868|26|NC_019693|CRISPRCasFinder
GTATTGACTGGCGCAGGATTGTTGAC
>48.2|4914922|23|NC_019693|CRISPRCasFinder
ATGGGGGTGAGTGGGGTTTCTGC

CRISPR arrays and Neighbor proteins around NC_019693_48

CRISPR arrays

The CRISPR arrays of NC_019693_48

>merge|NC_019693|48|4914840-4914972|CRISPRCasFinder
TGGCGCAGGATTGTTGACTGGCGCAGGAGTATTGACTGGCGCAGGATTGTTGACTGGCGCAGGATTGTTGACTGGCGCAGGAATGGGGGTGAGTGGGGTTTCTGCTGGCGCTGGTACTTCTACTGGCGCTGGT

>NC_019693|48|47|4914840-4914972|CRISPRCasFinder
TGGCGCAGGATTGTTGACTGGCGCAGGA	GTATTGACTGGCGCAGGATTGTTGAC
TGGCGCAGGATTGTTGACTGGCGCAGGA	ATGGGGGTGAGTGGGGTTTCTGC
TGGCGCTGGTACTTCTACTGGCGCTGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_156823900.1|4922954_4924175_-|site-specific-DNA-methyltransferase	unknown	unknown	gnl|CDD|334588
NC_019693.1|WP_015150055.1|4910367_4911327_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_019693.1|WP_156823901.1|4927826_4928057_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_083896799.1|4905135_4906521_+|tetratricopeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|276809
NC_019693.1|WP_015150065.1|4928804_4929527_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NC_019693.1|WP_015150054.1|4907980_4909699_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl|CDD|224182
NC_019693.1|WP_015150053.1|4907299_4907530_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150067.1|4931809_4931965_+|hypothetical-protein	unknown	unknown	gnl|CDD|177361
NC_019693.1|WP_156823902.1|4929625_4929775_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150056.1|4911434_4912070_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|226983
NC_019693.1|WP_015150048.1|4899880_4901620_+|vanadium-dependent-haloperoxidase	unknown	unknown	gnl|CDD|239492
NC_019693.1|WP_015150066.1|4930358_4931663_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|236947
NC_019693.1|WP_015150058.1|4912609_4912840_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150061.1|4924396_4924927_-|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|239942
NC_019693.1|WP_015150068.1|4932199_4933363_-|RNA-polymerase-sigma-factor-RpoD	unknown	unknown	gnl|CDD|236012
NC_019693.1|WP_015150050.1|4903497_4904955_+|FHA-domain-containing-protein	unknown	unknown	gnl|CDD|99811
NC_019693.1|WP_015150062.1|4925173_4927714_-|NTP-transferase-domain-containing-protein	unknown	unknown	gnl|CDD|100097
NC_019693.1|WP_015150052.1|4906913_4907303_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350220
NC_019693.1|WP_156824077.1|4901753_4903406_+|4Fe-4S-binding-protein	unknown	unknown	gnl|CDD|378955
NC_019693.1|WP_015150064.1|4928558_4928741_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_156823900.1|4922954_4924175_-|site-specific-DNA-methyltransferase	gnl|CDD|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	4.05362e-51
NC_019693.1|WP_015150055.1|4910367_4911327_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	8.89487e-64
NC_019693.1|WP_083896799.1|4905135_4906521_+|tetratricopeptide-repeat-containing-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	3.81442e-10
NC_019693.1|WP_015150068.1|4932199_4933363_-|RNA-polymerase-sigma-factor-RpoD	gnl|CDD|236012	PRK07406, PRK07406, RNA polymerase sigma factor RpoD; Validated.	0
NC_019693.1|WP_015150052.1|4906913_4907303_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350220	cd09872, PIN_Sll0205-like, VapC-like PIN domain of Sll0205 protein and homologs. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of the Synechocystis sp. (strain PCC 6803) Sll0205 protein and other uncharacterized homologs are included in this subfamily. They are similar to the PIN domains of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.3178e-35
NC_019693.1|WP_015150067.1|4931809_4931965_+|hypothetical-protein	gnl|CDD|177361	PHA02337, PHA02337, putative high light inducible protein.	2.971e-05
NC_019693.1|WP_015150056.1|4911434_4912070_+|Uma2-family-endonuclease	gnl|CDD|226983	COG4636, Uma2, Endonuclease, Uma2 family (restriction endonuclease fold) [General function prediction only].	1.84339e-14
NC_019693.1|WP_015150048.1|4899880_4901620_+|vanadium-dependent-haloperoxidase	gnl|CDD|239492	cd03398, PAP2_haloperoxidase, PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen peroxide forming dioxygen. They are likely to participate in the biosynthesis of halogenated natural products, such as volatile halogenated hydrocarbons, chiral halogenated terpenes, acetogenins and indoles.	3.87577e-63
NC_019693.1|WP_015150066.1|4930358_4931663_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	4.49935e-165
NC_019693.1|WP_015150054.1|4907980_4909699_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl|CDD|224182	COG1262, COG1262, Uncharacterized conserved protein [Function unknown].	3.05651e-76
NC_019693.1|WP_015150061.1|4924396_4924927_-|single-stranded-DNA-binding-protein	gnl|CDD|239942	cd04496, SSB_OBF, SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.	8.41126e-23
NC_019693.1|WP_015150050.1|4903497_4904955_+|FHA-domain-containing-protein	gnl|CDD|99811	cd06215, FNR_iron_sulfur_binding_1, Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently bound FAD as a prosthetic group) are present in chloroplasts, mitochondria, and bacteria in which they participate in a wide variety of redox metabolic pathways. The C-terminal portion of the FAD/NAD binding domain contains most of the NADP(H) binding residues and the N-terminal sub-domain interacts non-covalently with the isoalloxazine rings of the flavin molecule which lies largely in a large gap betweed the two domains. In this ferredoxin like sub-group, the FAD/NAD sub-domains is typically fused to a C-terminal iron-sulfur binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins which act as electron carriers in photosynthesis and ferredoxins which participate in redox chains from bacteria to mammals. Ferredoxin reductase first accepts one electron from reduced ferredoxin to form a flavin semiquinone intermediate. The enzyme then accepts a second electron to form FADH2 which then transfers two electrons and a proton to NADP+ to form NADPH.	1.41905e-124
NC_019693.1|WP_015150062.1|4925173_4927714_-|NTP-transferase-domain-containing-protein	gnl|CDD|100097	cd05805, MPG1_transferase, GTP-mannose-1-phosphate guanyltransferase (MPG1 transferase), also known as GDP-mannose pyrophosphorylase, is a bifunctional enzyme with both phosphomannose isomerase (PMI) activity and GDP-mannose phosphorylase (GMP) activity. The protein contains an N-terminal NTP transferase domain, an L-beta-H domain, and a C-terminal PGM-like domain that belongs to the alpha-D-phosphohexomutase superfamily. This subfamily is limited to bacteria and archaea. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this group appear to lack conserved residues necessary for metal binding and catalytic activity. Other members of this superfamily include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
NC_019693.1|WP_015150065.1|4928804_4929527_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	1.27381e-13
NC_019693.1|WP_156824077.1|4901753_4903406_+|4Fe-4S-binding-protein	gnl|CDD|378955	pfam12801, Fer4_5, 4Fe-4S binding domain. Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.	8.48059e-05

Protein sequences

>NC_019693.1|WP_015150058.1|4912609_4912840_+|hypothetical-protein
MSESPRLPPETFALGRIASLLVLIDVDGDCYIFPALPRRDESLRPPVVVIPRSREGDRLIQLRPTLDTDIPSGDNN
>NC_019693.1|WP_015150056.1|4911434_4912070_+|Uma2-family-endonuclease
MVQTPIPSHILYPDSDGKPMAENTLQYRWIVRLVTNLKQLLKDQIAFVAGDLLWYPVRVERPPAPCQAPDAMVAFGRPDGDRGSYKQWEEDNIAPQVVFEIISPSNTISEMTAKQNFYAQYGVLEMFFYDPQSHDFWGLHRATAQDSLMFINPDDLPWISPLLNIRFELSADGLAVYHPDGELFKEPGELFEERDRAFAKLREMGIDPETL
>NC_019693.1|WP_015150055.1|4910367_4911327_+|serine/threonine-protein-kinase
MTWEKGKTLKGGAYTIESVLGQGRFAITYLAHDRMGERVAIKTLNPDSSVLGQMSAADRQAFGSKFYDEALKLEKCKHPNIVPVRDVFEESVRAWFSQVRYACIVMDYIDGFDLEHRRSPRLPIAEVLRYGRQIGSALIAVHAQKILHRDVKPGNIIVRSHRGKSEAILIDFGLARAFEHPLTQKITSSGFAPIELYSNQLKRGPWTDVYGLAATLYELLTGKPPEDALARHDEDIAVDLTPPRCYVRQISKRVNQAIVQGLALMPDDRTPSVPQFLRQLGVGQWYVPFPDWDVNIWVQVGIMVGTLLGATATIIALLK
>NC_019693.1|WP_015150054.1|4907980_4909699_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MFWPDGHTLQNGKLVIDHVLGQGGFGITYKAIHRGFNAPVVIKTPNAYLRKDPEYPKYVKRFIREAQTLAKLEQNPHPNIVRVKDLFEEGDAHCLVMEFIDGTTLWDYVQQRGSLSETEALSYIRPIADALVQVHGVGLVHRDVTPMNIMLRDNRQPVLIDFGISGEIVPSSIISSKMFGNRAFAPYEQLIKGDRNPTVDIYTLAASLYYLITGQLPQDCFSRKVDNEPLIDPKDLVLVSQPINDAILKGMELLPKKRYTSMAAFLGLLSPAPAPPPEKIYHYEIITLNQQGEIAQRQKGQNRGVLETTLGLNLEMVVIPAGEFLMGLPENEAERSSAEGPQHRVILPEFLMSRTPITQAQWRIVAQIPQVVRSLEPDPAYFKGNNNPVEGVSWEDCIEFCLRLNQATGQPYRLPSEAEWEYACRAGTSTPYHFGPTLSPRVANYDGNYTYGQGKKGEYRKKTIPVGSLNAPNAWGLQDMHGNVWEWCLDDWHNSYEGAPTDGRAWIENDNHYQNIIDWLKDLLNKRSTHKLLRGGSWCHYPRYCRCAVRIHGTRDYENNSLGFRVVAPRTA
>NC_019693.1|WP_015150053.1|4907299_4907530_-|hypothetical-protein
MTEITTHELPQILQTLFIEVERTKTPITVIHEGKPLVIIYPATTPDARPPFGAMKGSGEILGDIIAPEPQPWEVLE
>NC_019693.1|WP_015150052.1|4906913_4907303_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MKLLLDTHIWLWYLLGDQRLSSQITTAIADPNTELWLSPISIWETLILAEKRRISLHPDPITWVNLALKTLKTHEAVMNYAIAILNRHISLPHQDPSDRFIVATAIYYGLTLATVDANITSNSAIQTVS
>NC_019693.1|WP_083896799.1|4905135_4906521_+|tetratricopeptide-repeat-containing-protein
MNLEWVTIEITRSVSFTMNEQRIPAYLTLIQKLLTSPRTQADEIINQHLELIDPGFLQLCQTLAEQFQEAGEEDRASFLLNLAQQLGGGIQGQDEGAVANVGGSRSPEDEYLDVLMALLKTKLENPNNPQAIEAVLVQYQDKLDLKFAEVVKEWFQSKIDPNYPERNEAVGVILNNLAIAFYQFPLGTRSHNIEIAVACYECALSVSTQATVPEQWAATQNNLGSAYQDRIQGDKSENLEAAIACYKAALQVYTQEDYPLDWAMTHNNLGNSYNIRVQGDPAQNVEAAIGCYIAAFEVYILEDFPQHWAMTHNNLGNTYRDRTQGDPSENIEQAISCYQNALQIRTRETFPPDWATTTSNLGEAYYKRVQGEKSDNIDQAISCYQNALQVNTREAYPQKWAHINQNLGRAYCDRVKGKKTQNIKQAISYYESALQVYTPDTFPEQAAITQNYLEEAKQQKS
>NC_019693.1|WP_015150050.1|4903497_4904955_+|FHA-domain-containing-protein
MLKLKQIDSQTGQVTEKILSRQTEFQTEWLMGRHPSCHIVLKSPEVSRIHGRIVWKNGEYGFTDLGSTDGSRLNNQEVQVNECWILKPDDTIRIGRYLLLIEEIELTHQPSFVNPSDRIRGTNLEVGVRCINAIAETADVKTFVFIAEDGIPWTYQPGQFVTLSLQIDGKTVRRSYSISSSPSRPHTLEITVKRVAPATAELPPGLVSNWLHDHITLGSEIKISQPMGQFTCGTEGHDKLLLISAGSGITPMMSMSRWICDTADSRDIIFIHSARSPDDLIFRRELEGMVARYPNFKLAFTVTRVEPGQVWSGYRGRLNESMLEAISPDFCDRTAYLCGPHAFMESVKSMLQTLDFPMNQYHEESFGGKKSSHLASEAIATGTAVPSVALLSLSAPLETSTSCESTTIIFAKSVRTVMCDGEDSILEIAEREGLDLPFGCRIGSCGVCKQKLIEGSVNYDNTPDCEKDYILTCVAKPVGRVAIDA
>NC_019693.1|WP_156824077.1|4901753_4903406_+|4Fe-4S-binding-protein
MHLIRVGLASAWLLLIASLFYDPISHHLTASINLFSPFRAARECVLVQGKCLDILQPYPIGMRIFWGIVIPSAIMILLVCGHETWRRICPLYFLSQIPRALGLKPRLNIHNNTWLVHHHLYLQFLLLFIGITSRILFINSHRILLGGFLLFTIASAIGVVYLYGGRSWCHYICPFGIVQIILTGPRGLLGSEAHQTPTASITQSMCRITDPLTGQEKPACMSCKSPCLDIDAERSYWEQLTKSGRKFIHYGYLGLVVGYVVYYYLYAGNWTYYFSGVWSHEANQLSSLLNPGFYISGQPIFIPKLMAAPLILGVCIVLAYLLGIKLEKAYKGYLKRRNSEIPPEQVLHRLFSIWTFAAFNVFFMYGGRPEILRFPVILQLLFNGLVVGVSTLWLARTWNRSVQDYTQESLAQKLARKLKKFPVDWSPCLDNRGLEALKANQIYILAQVLPLVTEQSRKMVYKGVIKEAIQSNNFKVYPGLDLWEWLRQQVGLTQLEHDAILREIQSENLGKGDGNDGEYRIRTEIGRPTRDISDRTQIRSPKPSHPRAGI
>NC_019693.1|WP_015150048.1|4899880_4901620_+|vanadium-dependent-haloperoxidase
MLDINNLYNEDYYLTQNPDVAAAVQSDAFSSGLDHFNQFGQGEHRTPSALFNPVYYLEQNRDVAEAVQSGQMASALEHYLNFGQIEGRNPSGLFNETLYRQANPDVAEAIDPVSGGFTNALHHYLEYGQEEGRDPHSRIVSLWSEAAQQAVRNTGPGPTIASRAYAIVMTAMFDTWAAYDETAIATQLGDTLQRPSAENTVSNKSEAMSYAAYRTLNDIFPTQGELFNQLMHQLGYDPTNTDTESETPSGIGNRSAQALLDFRHHDGSNQLNGYEDITGYQPVNTHDTVVMGDRWQPLSSPLNDPNGTVQQFLTPQWGEVIPFSLTSGDQFRPEAPPALGTPLFEQRAREVLEISANLTDEQKMIAEFWEDGAGTSFPPGKWMNFGQFVSERDAHTLDQDIQMFFTLSNSLLDAGIASWEAKTYYDYVRPITAIRELFAGEQVEAWGGPGQGTQTIGGSQWHPYQHSASPTPPFSEYVSGHSTFSAAAAEILQRFTGSDEFGGSITIALGDSVIESGNTPTTDITLAWPTFSTAADQSGLSRIYGGIHFYEGDVHGRTLGRNVGESVWNRAQLFIQGIA
>NC_019693.1|WP_156823900.1|4922954_4924175_-|site-specific-DNA-methyltransferase
MPMKVFTGDCLNLLEQIPDESVNAIYLDPPFFTEKIHKLKTRDGSKEFSFDDLWGCHKKYAEFLYQRLVPLHRVLKSSGSIFVHCDTTANYLIRSLLNEVFGPDQFRSEIIWHYKRWSNSKKGLLPAHQTIYFYSKTNSFTFNPHYTNYSESTNVDQILQRRSRNSQGKSIYARDEQGEVILNDSKKGVPLSDVWDIPYLNPKAKERVGYPTQKPILLLERIIEIATHPGDLILDPFCGSGTTLVAAQLLGRHGIGMDISADAIELTQQRLVNPIKTASNLLEKGRYSYLTANPDALALLQGLDAIPVHRNKGIDAILKQQFNNKPILVRVQRPGESLLDAVRLLSKAAQTKGSHCSILIRTEPLESVPKEVIPAFIQIIDAPALEIVEILHDLSSKCSYIGEKVK
>NC_019693.1|WP_015150061.1|4924396_4924927_-|single-stranded-DNA-binding-protein
MNNCILMAQIIQEPQLRYTSDNLAIAEMLVEFTTYRQNDPPAHLKVIGWGNFAQELHSNYRVGDRVVIEGRLSMNTVERPEGFKEKRAELVAQRIHSLGEQTGSASSPSNATPATNVVALESRRSTAPAATDQGRSPAAHTPTPSEPTAASRVSPPPARTSYQQPPVDDPEDEIPF
>NC_019693.1|WP_015150062.1|4925173_4927714_-|NTP-transferase-domain-containing-protein
MRAVLMAGGSGTRLRPLTCDLPKPMVPILNRPIAEHIVNLLRRHHITEIIATLHYLPDVMRDYFQDGNEFGVQMTYAVEEDQPLGTAGCVKNIAELLDETFLVISGDSITDFDLTAAIKFHKEKGSKATLVLTRVPNPVEFGVVITDEQLRIQRFLEKPSTSEIFSDTVNTGIYILEPEVLDYLPANQESDFSKDLFPLLLEKGDPMYGYIAEGYWCDVGHLDAYRESQYDGLLEKVKLDFAYELRSPGLWIGQNTFIDPSAKIETPVVIGDNCRIGARAKLESGTILGDNVTIGSDADLKRPIVWNGAIIGDEAHLRACVACRGVRVDRRAHVLEGAVVGSLSSVGEEAQISPGVRVWPSKKIESGATLNINLIWGQAAQRNLFAQRGVSGLANIDITPEFAVKLGAAYGSTLQPGASITVSRDQRSISRMVSRSLIAGLMSVGTHVQNLEATAIPVARYIVPTLSVEGGLHVRLHPERPDSLLIEFFDNKGINISKAREKKIEGAYFKEDFRRAQIQEIGNMAYPSQVLDLYSTGFEKHLNVEAIRYSNSKVVIDYAYSVSGAVLPQLLAKFGSDAVVLNASLSQMAPVNEERENLLLQLGQVVEALHANFGVQVSANGELLILVDESGSPIRGELLTAVMVQMILTTNPRSTVVVPVHASSAVEHIARRHDGKVIRTKANPTALMEACHTNPNVVLGGSGDMGFIFPELHPGFDAMFCIAKAIEMLTIQEESLGQVRAEVPRVCHKTLTVRCPWTVKGALMRHLVETHPADNLELIDGVKIFDRPHDDSWVLILPDAGEPMVHIFANSSDREWVDTSLMQYRKYVQDFVQEQEGGDMNMSGDN
>NC_019693.1|WP_156823901.1|4927826_4928057_-|hypothetical-protein
MWDRNGDRPRFMRWDPNIYLEDGDRAVPFAQGLNLYRKQKAAYDTDESPIKSVKPRATPTPPAEVQREERGPGDRS
>NC_019693.1|WP_015150064.1|4928558_4928741_+|hypothetical-protein
MMQLVGLAFLVLYAAGGWKFWKGFRRTNFTEGRLYLTLLWPVLVVNKSYRKNFTKALKGR
>NC_019693.1|WP_015150065.1|4928804_4929527_+|class-I-SAM-dependent-methyltransferase
MSKVSNSSPPNAEFLGPDPWQTRLSPVASRFNQEYQGDPIELPPEVESMPIFHDRVSGALQASQVSPFWDIAKPKKNQRCLDIGCGVSFLVYPWRDWGAYFYGQEISTVARDALNSRGPQLNSKLFKGVCLGPAHRLSYGEDAFDLAIATGFSCYYPLAYWTDVLGQVKRVLKPDGSFVFDVVNPEATLAENWGILEMYLGTEVFLEPIPEWEKLIKASGCKILKRSEGKLFSMYKVKFE
>NC_019693.1|WP_156823902.1|4929625_4929775_+|hypothetical-protein
MRVTPSIWGIGDTRKSRELAQFLALNHLPRKISVTTESARSLYPSAPLL
>NC_019693.1|WP_015150066.1|4930358_4931663_+|ATP-binding-cassette-domain-containing-protein
MARVVIENVYKSYGDRREKSTPVPPDGILGTDDTSTPGLKPAQILRRINLTVEDGEFMVLVGPSGCGKSTLLRLIAGLEELTAGNIWVGDRLLNDLPPKDRDIAMVFQNYALYPHLKVYDNIAFGLRRTLVMNEATSEGTEVRDDATSVPNWAEDALVSMTRNLPKYLRYLSPKEREVDQRVRTVAGLLQIEALLDRLPKQLSGGQKQRVALGRAMARNPQVFLMDEPLSNLDAKLRAETRSQIVKLQRQLETTTIYVTHDQTEAMTMGDRIAVMNAGQIQQIAAPLELYHRPANLFVAEFIGSPPMNFIPVQFKAPLSITHDSFRFTLPEYWGTALQGYDGRSLILGIRPEHLSVSPAATKNMKVKVDLVEALGSETYIVGTLPDHDLPKPIQARIEPDWMVHPGEEIWLAIALEKIHLFDQETGRAILASDR
>NC_019693.1|WP_015150067.1|4931809_4931965_+|hypothetical-protein
MIEPQPRNRWNWGFTPSAENWNGRLAMIGFISAVVLELTTGQGVLHFLGII
>NC_019693.1|WP_015150068.1|4932199_4933363_-|RNA-polymerase-sigma-factor-RpoD
MTQANNVLAPVEKTDIKSIGESQHDLEILIETDDEPLISIDEDEFLGAVSEDDDPKATKARSTRRRAQPKKKHYTEDSIRLYLQEIGRIRLLRADEEIELARKIADLLELERIREHLCDHLHREPYDAEWADAVKMSVGQFRHRLHCGRRAKDKMVQSNLRLVVSIAKKYMNRGLSFQDLIQEGSLGLIRAAEKFDHEKGYKFSTYATWWIRQAITRAIADQSRTIRLPVHLYETISRIKKTTKLLSQEMGRKPTEEEIATRMEMTIEKLRFIAKSAQLPISLETPIGKEEDSRLGDFIESDGETPEDQVSKNLLREDLESVLDTLSPRERDVLRLRYGLDDGRMKTLEEIGQIFNVTRERIRQIEAKALRKLRHPNRNSILKEYIR

Crispr_ID: NC_019693_49

• CRISPR_ID: NC_019693_49
• CRISPR_location: 4965719-4965809
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: RT

Consensus repeat of NC_019693_49

Consensus_repeat	Method
TGTCCCCCCCCGGGAACCTTCCTGCGGT	CRISPRCasFinder

spacers of NC_019693_49

>49.1|4965747|35|NC_019693|CRISPRCasFinder
GTGGATACATTATGATAAACTTACTTTCAGCACTG

CRISPR arrays and Neighbor proteins around NC_019693_49

CRISPR arrays

The CRISPR arrays of NC_019693_49

>merge|NC_019693|49|4965719-4965809|CRISPRCasFinder
TGTCCCCCCCCGGGAACCTTCCTGCGGTGTGGATACATTATGATAAACTTACTTTCAGCACTGTGTCCCCCCCCGGGCACCTTCCTGCGGT

>NC_019693|49|48|4965719-4965809|CRISPRCasFinder
TGTCCCCCCCCGGGAACCTTCCTGCGGT	GTGGATACATTATGATAAACTTACTTTCAGCACTG
TGTCCCCCCCCGGGCACCTTCCTGCGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015150093.1|4963347_4963578_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150097.1|4970419_4973011_-|diguanylate-cyclase	unknown	unknown	gnl|CDD|143635
NC_019693.1|WP_015150094.1|4963655_4964990_-|DNA-processing-protein-DprA	unknown	unknown	gnl|CDD|223829
NC_019693.1|WP_052315838.1|4958343_4958616_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150090.1|4958854_4959823_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150088.1|4956434_4956929_-|DUF427-domain-containing-protein	unknown	unknown	gnl|CDD|225220
NC_019693.1|WP_015150095.1|4966236_4966467_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_083896801.1|4988232_4990326_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|227328
NC_019693.1|WP_015150092.1|4961745_4963092_+|protein-kinase	unknown	unknown	gnl|CDD|319862
NC_019693.1|WP_156824055.1|4990634_4992380_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209
NC_019693.1|WP_044197505.1|4973519_4974599_+|tocopherol-cyclase	unknown	unknown	gnl|CDD|372979
NC_019693.1|WP_015150100.1|4982078_4988336_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|368641
NC_019693.1|WP_044195496.1|4974970_4981759_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|227328
NC_019693.1|WP_156824078.1|4955224_4955743_-|O-acetyl-ADP-ribose-deacetylase	unknown	unknown	gnl|CDD|394878
NC_019693.1|WP_015150102.1|4993361_4994801_+|phosphoglucomutase/phosphomannomutase-family-protein	unknown	unknown	gnl|CDD|100093
NC_019693.1|WP_015150096.1|4966565_4970003_-|isoleucine--tRNA-ligase	unknown	unknown	gnl|CDD|235588
NC_019693.1|WP_156823903.1|4965964_4966153_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150087.1|4955783_4956341_+|NUDIX-hydrolase	unknown	unknown	gnl|CDD|239516
NC_019693.1|WP_015150091.1|4960164_4961505_+|protein-kinase	unknown	unknown	gnl|CDD|319862
NC_019693.1|WP_015150089.1|4957084_4958062_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_156824055.1|4990634_4992380_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	2.5e-47	155.9	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015150097.1|4970419_4973011_-|diguanylate-cyclase	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.28883e-68
NC_019693.1|WP_156824055.1|4990634_4992380_-|group-II-intron-reverse-transcriptase/maturase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	2.07589e-125
NC_019693.1|WP_015150094.1|4963655_4964990_-|DNA-processing-protein-DprA	gnl|CDD|223829	COG0758, Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion].	2.11076e-51
NC_019693.1|WP_083896801.1|4988232_4990326_+|CHAT-domain-containing-protein	gnl|CDD|227328	COG4995, COG4995, Uncharacterized protein conserved in bacteria [Function unknown].	8.33526e-112
NC_019693.1|WP_015150088.1|4956434_4956929_-|DUF427-domain-containing-protein	gnl|CDD|225220	COG2343, COG2343, Uncharacterized protein conserved in bacteria [Function unknown].	7.33534e-55
NC_019693.1|WP_015150092.1|4961745_4963092_+|protein-kinase	gnl|CDD|319862	cd16383, GUN4, porphyrin-binding protein domain GUN4. GUN4 is a porphyrin-binding protein involved in chlorophyll biosynthesis regulation and intracellular signaling, found in aerobic photosynthetic organisms. It has been implicated in retrograde signalling between the chloroplast and nucleus. GUN4 can bind protoporphyrin IX (PIX) and magnesium protoporphyrin IX (MgPIX), substrate and product of the Mg-chelatase, as well as heme and cobalt protoporphyrin IX (CoPIX). It may play a role in protecting plants from reactive oxygen species (ROS)-mediated damage.	8.15824e-73
NC_019693.1|WP_044197505.1|4973519_4974599_+|tocopherol-cyclase	gnl|CDD|372979	pfam14249, Tocopherol_cycl, Tocopherol cyclase. This family contains tocopherol cyclases. These enzymes are involved in the synthesis of tocopherols and tocotrienols (vitamin E).	0
NC_019693.1|WP_015150100.1|4982078_4988336_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl|CDD|368641	pfam05860, Haemagg_act, haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins.	2.50808e-20
NC_019693.1|WP_044195496.1|4974970_4981759_+|CHAT-domain-containing-protein	gnl|CDD|227328	COG4995, COG4995, Uncharacterized protein conserved in bacteria [Function unknown].	6.34259e-115
NC_019693.1|WP_156824078.1|4955224_4955743_-|O-acetyl-ADP-ribose-deacetylase	gnl|CDD|394878	cd02908, Macro_OAADPr_deacetylase, macrodomain, O-acetyl-ADP-ribose (OAADPr) family. Macrodomains are found in a variety of proteins with diverse cellular functions, as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Macrodomains can recognize ADP-ribose (ADPr) in both its free and protein-linked forms, in related ligands, such as O-acyl-ADP-ribose (OAADPr), and even in ligands unrelated to ADPr. This family includes eukaryotic macrodomain proteins such as human MacroD1 and MacroD2, and bacterial proteins such as Escherichia coli YmdB; these have been shown to be O-acetyl-ADP-ribose (OAADPr) deacetylases that efficiently catalyze the hydrolysis of OAADPr to produce ADP-ribose and free acetate. OAADPr is a sirtuin reaction product generated from the NAD+-dependent protein deacetylation reactions and has been implicated as a signaling molecule. By acting on mono-ADP-ribosylated substrates, OAADPr deacteylases may reverse cellular ADP-ribosylation.	3.01849e-98
NC_019693.1|WP_015150096.1|4966565_4970003_-|isoleucine--tRNA-ligase	gnl|CDD|235588	PRK05743, ileS, isoleucyl-tRNA synthetase; Reviewed.	0
NC_019693.1|WP_015150102.1|4993361_4994801_+|phosphoglucomutase/phosphomannomutase-family-protein	gnl|CDD|100093	cd05800, PGM_like2, This PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily and is found in both archaea and bacteria. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four structural domains (subdomains) with a centrally located active site formed by four loops, one from each subdomain. All four subdomains are included in this alignment model.	0
NC_019693.1|WP_015150087.1|4955783_4956341_+|NUDIX-hydrolase	gnl|CDD|239516	cd03424, ADPRase_NUDT5, ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, for its activity. It also contains a highly conserved 23-residue Nudix motif (GX5EX7REUXEEXGU, where U = I, L or V) which functions as a metal binding site/catalytic site. In addition to the Nudix motif, there are additional conserved amino acid residues, distal from the signature sequence, that correlate with substrate specificity. In humans, there are four distinct ADPRase activities, three putative cytosolic enzymes (ADPRase-I, -II, and -Mn) and a single mitochondrial enzyme (ADPRase-m). Human ADPRase-II is also referred to as NUDT5. It lacks the N-terminal target sequence unique to mitochondrial ADPRase. The different cytosolic types are distinguished by their specificities for substrate and specific requirement for metal ions. NUDT5 forms a homodimer.	9.11823e-45
NC_019693.1|WP_015150091.1|4960164_4961505_+|protein-kinase	gnl|CDD|319862	cd16383, GUN4, porphyrin-binding protein domain GUN4. GUN4 is a porphyrin-binding protein involved in chlorophyll biosynthesis regulation and intracellular signaling, found in aerobic photosynthetic organisms. It has been implicated in retrograde signalling between the chloroplast and nucleus. GUN4 can bind protoporphyrin IX (PIX) and magnesium protoporphyrin IX (MgPIX), substrate and product of the Mg-chelatase, as well as heme and cobalt protoporphyrin IX (CoPIX). It may play a role in protecting plants from reactive oxygen species (ROS)-mediated damage.	9.04679e-72
NC_019693.1|WP_015150089.1|4957084_4958062_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	5.13461e-58

Protein sequences

>NC_019693.1|WP_015150094.1|4963655_4964990_-|DNA-processing-protein-DprA
MLTHILPPDTQAILLLCESFGQNRQTEPQPLTLSEYNQVAQWLRENQLKPSDLLEDAGKKQLEKMPTPGKLTGDRLLGLLERGAMLAFAVGKWTNQGIWILARSDRLYPKRLKQQLKHSSPAILYGVGNQNLLDAGGLAVVGSRDLDEEGKEYSQNVAETCAQQDIQIVSGGAKGVDSVAMLGAVLSGGTALGILAHSLTKTAVSSQYRTAIREGKLTLVTAYDPDAGFTVGNAMGRNKYIYAAADYALIVSSAMGEGGTWAGAIEALKRLPNVPVFVRNQGNIPPGNRELIQQGAKPFPLSPWQDSLLELLQNTASQAEPLPVQEERLALDFNPATVAENSVSDEEKTSPVNPTPEPPTEPPANPPAMTRPKDIYHAVLPLIVEQLEQPKDEKSLAEVLEVQVGQLRQWLKKAVEEGKVIKKTKPVQYVINTEATQLSLLEDC
>NC_019693.1|WP_015150093.1|4963347_4963578_+|hypothetical-protein
MQAERLILETDELGNLKQIPKLPPNKQVEVIFRVLDEAKDPAIKRRVPHPDLVGKIKILSDNIMDSVPESDWELLQ
>NC_019693.1|WP_015150092.1|4961745_4963092_+|protein-kinase
MVWSDGYQLQSRDYRIARVLGQGGFGITYQARHLKLDQDFVIKTPNEHLKFDPDYPKFVDRFIKEGQRIAKLCTNPHPHIVRVFDLFQEGDTHCMVMDFIPGESLWQRVQGRGALPEVEAVTYFQQIGGALQRVHEAGLVHRDAHPGNIMFRGDEAVLIDFGIAGEIVPVTISYKPFGNEAFAPLEQRKGFREPTVDIYTLSASLYYALTGERPASSFDRKIDDVELVPPKQLVRSLSDTVNKAVLKGMELKPQDRPQTMGEWLSVLQPPIPTTTVSPGYQKLDRTRVSPGYQKLDRTRVSPHYEKLQQFLAAGKWREADEETARVMLLVAGREEEGWLDENSINQFPCEDLRRIDGLWVQYSNGRFGFSVQKRIWQECGGKVDYETKCRLGDRVGWRRRDKWLEYHELTFSTMTPPGHLPLGLGTGWGVWEVWNTSSLVARLINCNL
>NC_019693.1|WP_015150091.1|4960164_4961505_+|protein-kinase
MVWPNGHQLQSQNYRIEGVLGQRGFGITYQARHLNRDQDFVIKTPNEDLRFDPNYPKFVDRFIKEGECIESIAGICTRPHPYIVRVFDLFQEGETHCIVMDFIPGESLWQRVQRQGALSEVEAVRYFQQIGGALQELHEAGLVHRNAHPGNIMFRGDQTPLIDFGIAVEIVPVTISFNHSWNSAFSPLEQMKGSREPTVDIYTLSASLYYALSGEYPTSSVERKIDDVELLTPKELVPSLSDRINEAVLKGMELTPHNRPQTMDEWVSLLESPIPTTVSHRYQKLQQLLAAGKWWEADAETRQVMLQVAGREQQGWFDEDSINQFPCEDLLQIDDLWVQYSNGRFGFSVQKRIWQECGGQVNWGTSIRLGDRVGWRKDGKWLELEELTFSSNAPPGHLPQSIPLELIKWGVRADLESGGRKFKKARNFCKKMGMRFFSRVQTCHKN
>NC_019693.1|WP_015150090.1|4958854_4959823_-|hypothetical-protein
MEYESVKADYDAPWKEALTLYFEQFLSFFFPDIHSQIDWSQPYQSLDKELLELGRDSEVGTQFPDKLFEVKLITGQLLWILIHVEIQSQYIKDFGQRIYQYNYRAFDQYNKPVVSIAILGDDTASWRPTEYAYTLDGYELKLKFPTVKLLDYQTQWEQLESEQNPFALMVMAHLKTQATNRQMEERKQWKWTLIRSLFDRGYRREEVENLFRFIDRMMSLPKQLEQQLRTQLIEYREERQMPFISPMEELIQEEAMERGILKNQRENILELLQVRFGEVPQSVVEAVNRLEEIPTLKQLLRQTISVGSVAEFEQLLNPRTDS
>NC_019693.1|WP_052315838.1|4958343_4958616_-|hypothetical-protein
MPFISPMEELIREEAMEQGLEQGLEQGTLRNQRENILDLLQVRFGEVPQSVVEAVNRLEEIPTLKQLLRQTISVGSIAEFEQLLNPSTDS
>NC_019693.1|WP_015150089.1|4957084_4958062_+|serine/threonine-protein-kinase
MTLTVGQSIQGGRYTIEKVLGRGRFGITYKAKDAAGNAVAIKTLNDSLLHQLSPAEIEDLECKFWNEAVKLAKCSHNRHIVQVQELLNKGDVPCILMEYIDGVDLASRAQKQLPEKLALQYIQQIGEALIEVHSHQLLHLDIKPDNIVLRGGTAEAVLIDFGLARGFDHPLTTTRYSAEGYSALEMYSQKRPRGTYTDVYGLAATLYELLTGQVPVSAIKRKEEDARLIPPKEINRNISDRTNQAILKGLALDGCDRTQTVQEWLKLLGVKKPIPLPNWNAMEWCTAVIAAGTIGLLMIGLLTYLNPHSAPPSNPETPTSETIQP
>NC_019693.1|WP_015150088.1|4956434_4956929_-|DUF427-domain-containing-protein
MHPQRIEPGPGQESVWDYPRPPRLEEVTKHIQIIFNGEIIADTHHAKRVLETSHPPSYYLPPEDIKMEYLSQTPRSSFCEWKGSAGYYTVTVKEKQAPNCAWFYPSPTPEFEGIKDYVAFYPEMMDVCYVEGEEVQPQPGGFYGGWITSDIVGPFKGIPGSWGW
>NC_019693.1|WP_015150087.1|4955783_4956341_+|NUDIX-hydrolase
MKELKKWKQLRSRLVFDNQWCKVRQDEIQLPTGQIIDDFFVNVRPDIALVVPVTPQQEIVFVRQYRHGVGEILLELPAGAFHPETEKAEAAAAREMTEETGYHCPNLIKLATLYDNPVKDTNAIHIFLGKDAKNSGQQILDITEEIEVVLVPIHALLEKITQGEICVSGSVAAVFLALNHLKISL
>NC_019693.1|WP_156824078.1|4955224_4955743_-|O-acetyl-ADP-ribose-deacetylase
MTDKITVIQGDITKQQVDAIVNAANTRLLGGGGVDGAIHRAAGSGLLAECRTLNGCETGEAKMTRGYNLPAKYVIHTVGPVWKGGRNHEDELLASCYYESLKLAEKHHLKTIAFPAISTGVYGFPMERAAAIAVKRVEQFLSKTTVISQVRFVCFSNESYQCHLTAIATNNP
>NC_019693.1|WP_156823903.1|4965964_4966153_-|hypothetical-protein
MSLPWDRWDAMAAEIDAIASQFVLANCYDPRVASLQFFHWVDEGPPHSQTPAVPGKGTARER
>NC_019693.1|WP_015150095.1|4966236_4966467_+|hypothetical-protein
MQVERLILETDGLGNLKQIPKLPPNKQVEVIFRVLDDAKDSAIKRRIPHPDLAGKITILSDNIMDSVPESDWELLQ
>NC_019693.1|WP_015150096.1|4966565_4970003_-|isoleucine--tRNA-ligase
MTEAKTYKDTVNLPKTGFDMRANAVKREPELQKFWADHQIYERLSQNNPGELFILHDGPPYANGSLHMGHALNKVLKDIINKYKLLRGHQVRYVPGWDCHGLPIELKVLQAMKSKERQNLTPLTLRQKAQEFALKTVEEQKESFKRYGIWGDWENPYLTLKPEYEAAQIGVFGKMVLKGYIYRGRKPVHWSPSSQTALAEAELEYPEGHTSRSIYAAFQITKLADTASDLKAYMKQLWVGIWTTTPWTIPGNLAVSVNPQLEYAVVETAADYEPASGKFLIVAAELVDRLSETLGTSLTVKAKIKGKDLEGCEYKHPLCDRTSPVVIGGDYVTTESGTGLVHTAPGHGLEDYQVGQRYGLPILAPVDGNGNFTEEAGEFAGLNVLDEGNTAVIEALKTAKSLLKEEPYVHKYPYDWRTKKPTIFRATEQWFASVDGFREEAMKAISEVKWVPAQGENRIKGMVSERSDWCISRQRSWGVPIPVFYEEETGEPLMTEETIAHVQAIVAEKGSDAWWELPIEDLLPEPYRSNGKTYRKGTDTMDVWFDSGSSWAAVVGGREELRYPADLYLEGSDQHRGWFQSSLLTSVANNSIAPYKSVLTHGFVLDENNRKMSKSLGNVVDPATIINGGSNQKQEPPYGADVLRLWVSSVDYSSDVPIGKNILKQLSDVYRKIRNTARFLLGNLEDFDPAKDAVPYEELPELDRYMLHRMTEIFAEVTDAFESYQFFRFFQTVQNFCVVDLSNFYLDIAKDRLYISAVDAKRRRSCQTVLAIALENLAKAVAPVLCHIAEDIWQNLPYPTPYNSVFEAGWVQVEDHWKQPELAKTWQTLRQLRGEVNQVLEKARQDKAVGSSLEAKLLLYVEDVKLRQTLQNLNPARSVGTVPTTTTVANPPEETKGSATIANIPEETTQETTATPPSPEDIPQWQQLLNAALAVMAELPRYLGVFFSDYRRPLLSVGLIVSATVSTIVLGAIVDAIADFPLLPGLLELIGIGYSGWFVNRYVLRANNRQELTDTIASVSNYVLGKTQTDAAIDALEAFEEAMEEAIHPVTVPSPTPGVAVSQSVGNGVDELRYLFITSQVEVLDNPQRLEALKYSAQVNGWGIGVVDAEGQKCDRCWNYSTHVGESEEDPTICDRCVAALAGEF
>NC_019693.1|WP_015150097.1|4970419_4973011_-|diguanylate-cyclase
MIQANRLLCSFDIESAIDRNVQIVSADTPLIEAIALMKSQGQSADSTVSSYQQTAESFSGQEGVEPCLFVMNETHEIGLLTPRDILEFLGTEKSWKKTPIAAVMQKCSISLKESDCFDICTILNWFQQGVHYLPVLSDSTHQIVGCITPSRLLQRFYVAPPGKIINNSVQAQHQEQGEISVQNYPKKSLISKFKSLSNSSTIGYKKRPEGRIGHRIKIMPYMKKTAARSKSLTFLSCLRKTSLDSNCLTQNFPDIFSVMNFQNSRQILTENDRIFLKVFAAMTEIILVIDKRANLIKIAPTHPVVHRSEENSQLISQTLDFFFNGSQAETFLGPIRESLQTQTPIRFDYLLNLGKQQKKFTANISPLSNHSVIWAAQDITEHYQTIQALQYSESLLRGVLNSSLDGIMAFKAIRNSEGTIIDFQWLTINPIAEKIVGRRREDVLGKYLLQEMPGNLETGLFQRYVEVVNTQEPLELEFYYNHEGIQAWFKMMAVKLDDGFTVTFRNITEDKQAEATLQQANDKLIRWVEELKQRNREMALLGEMNELLQACETLEEAYKAIGLKLPQLFPSCSGGLAAINSFTNRVETVATWGKLPGSKPWFSPHECWALRRGRSHRVDNSPFSLFCDHLHSHLSPVESLCIPMMAQGEISGLLYLICSYKGRLSDAKQQLARTVSEQIALALANIKLRETLHTQSIRDSLTGLFNRRYLEETLERELQRAHRQDQSVGIVMIDIDHFKHFNDTFGHDAGDAVLRQVGELLMKNIRGSDIACRYGGEELTLILPDATLSETYRRAEQIREAIKNLVLEHRGELLGIITASLGIACYPTAGVTGDDLIRAADTALYRAKALGRDRVVTAGSYPI
>NC_019693.1|WP_044197505.1|4973519_4974599_+|tocopherol-cyclase
MTRLERETPHSGYHWNSSPRRFFEGWYYRVTLPTDRQTFAFMYSIEDPTGGSPYSGGGAQILGPDDGYLCRTFPDVKGFWAWSSSLALGHWGKTELPYPPNYLSPHEFDHYIEQGYQGTATWHQGKLCDPGTGQRCEWQYAISPVYGWGDRQRGQLATAGLLSFLPMFEPGWQILMAHGLATGWIDWNGKRYEFANAPAYAEKNWGGAFPEKWFWVNCNCFDDEPDLALTAGGGRRGVLWWMESVALICIHYRGEFYEFVPWNAQVSWEIDPWGRWQMQASNDRFTVELTATTDQPGTRLRAPTQEGLTFVCRDTMQGHLTLTLRSRLGNPGEIIFQATSSLCGVETGGGPWTETWRSA
>NC_019693.1|WP_044195496.1|4974970_4981759_+|CHAT-domain-containing-protein
MTQKRGTFEMKIKLQTLHLWVIIATLLASFLRSQPAISQVVTPAHDGTGTQVTPEGNHFHIQGGQLSKDGANLFHSFQHFGLTPGQIANFLSNPEIRNILGRVVGGDPSFINGLIQVSGGNSNLFLVNPAGILFGLNASLNLPGDFLATTATGIGLGDDQWLNVLGENQWAMLVGEPQHFSFAGLQPGAVANLGHLTLQPGSNLTLLGGTVLNAGTLSVPGGTITLAAVPGESVVSLSQTGHLLTLSIEREAFAGTANSSHALPMTPLSLPELLTGGMASHATGVEVQADGTIALTGSGPKITPETGTTIASGTLDVSNHRSEIPSTQSITLVGDRIAVLDAQLDASGITGGGTLRIGGEERGRGAIANATHSFISGESLITADALSSGNGGRVVIWADDTTAFYGTIQARGGSHSGSNGGTVEVSGKQQLIFRGNIDLTAPNGNVGTLLLDPENIIIVSGNGGTQDHEITDGTIQFGEAGDTFTLSEVALEGISENASVILEATNDITLQPLEDNRLDFTPGTGGLTFKADADGDGIGSFSMSEGDTIFTNGRNITIEAAEIQVGGINTASDNRNSGDINLTAQFDIRLTGGLTANAVGIYNGGNITLTSHAGAVDTQANFLSSWTEEGNAGSVTLQGFENILTGQINAESKGSGIGGNITLESATGTINTQRGDIFSQSNLGDAGDVSFTAYGDITTQSIVSNSDGEGSLGNGGNITLTSIAGAVDTTAGFITSWTEEGNAGLVTLAAFGDIQTGMIDSKAAGGGNGGNITLTSTAGEIIARPTAQPTGEQPQDFGLYSRSVLGDSGDVSLTAYGNIITSNIYADSDGEGSLGNGGNIILTSETGAVDTTTGYLSSWGGGDAGSVTLQAFGDILTGVIDSKAAGGGNGGNITLTSITGAINTAPNGAATLEENQGIGLYSFSSFGNSGQVSLTAPGNITTGNIWSDSREGTQGNGGNITLTSTTGAIDTRAGYLSSWAGGNAGSVTLQAFGPILTGIIDSYAQGSGTGGDITLASTTGAIDTSSAFWFDSSSEQGNAGNIIFNAPGDISVSSIRSFSGGSGRGGDITLESYTGKIEISAELDSSSATGSGGTIRIAALGDILTGYVSSYSGGDASGIGGNIEITSTTGAIDTTWGWIGGIRKTREQDQTLTEAAIASTDDVTDPDIANTFADPSTIANIDAYAARGTGGNVTLTAAQGIVTRDISAYGGQNSGSVSLETRSGDIQTGVIFSVSEQGNGGNIRLNADNGNITTSHLNTYVNQGGTGGQINVTSGGTFNIGAATINSFSTAGIAGDVRINANGDIILGGDRNRSAVRSQGEQQGGNLSITSNTGEILSWFGSLDSYSPAGNAGNVNLLAQSDIYTNGVLSQGQTQGGDINLTSTEGVTATNWGPLQSFSEQGIAGDVSVVAPGAITTGAILSQGLQQGGNITLTSREGLIDTSRGELRSLSDQGSAGHVSIQSEGTLTTGSIFSQGDRAGGDINLISNSVNSIEVQGELETLSNRGMAGNVYLYSPGNIRTTSILSQGLMRGGNITITSTEGAIFNRGDLNSYSEQGTAGKIILDASGEISTHAIASYGWIESGDVQLTSQNLGITTGNITTLADNGPTGNIIITAPGFAGDIFTGNLSAIGTAAGSIINTAGGNLVSGDQTISSSGDNTGEIINTVEGDATIGDQTITAGGDNTGSITNTIDGDATIGDQTITAGGDNTGSITNTIGGDATIGDQTISAGGDNTGNITNTIGGDATIGDQTITAGGDNTGSITNTIGGDATIGIQDINAEGDNFGKIVNTIEGEGTITAQGTSAGGINLGEIINNAEALTVIQTSQTPSQTLELNQDTAAKISQNLTAIQGNVIGTSGSQAIALLEQNRTQEYEDYFGRDLSSQAVSPASVRDALSAIARQTGNRSAVIYINALADELELLVFTPEGEPIRKTVPNLPRQDVIDLAIQFRQILTNPRYQGSPVYLKSAQQLYQWLIAPVASELEALEINTLLFSLDEGLRSLPLAALHDGEQFLVEHYSLALIPSMGLIDTQYQSLQGSRVLAMGASEFTELSALPAVPVELEAIAGQLWQGEEFLNEQFTLENLRTQRSQHPYRIIHLATHAEFQPGPLTNSYIQLWNEQLDLEGLRSLGWNDLPVELLVLSACRTAVGDRHAELGFAGLAIQSGVKSALASLWYVSDEGTLALMTEFYSHLGQSTIKAEALREAQIAMLRGEVQIEAGELRGSGTRGSVTLPPLLAKNKTVNLSHPYFWSSFTLIGNPW
>NC_019693.1|WP_015150100.1|4982078_4988336_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MKLDGITFQWLVIFSLLGSLSPVNPASAQPITPAADGTNTVVTPEGDRLDISGGSLSQDGANLFHSFQQFGLSQGQIANFLSNPEIRNILGRVVGGDASYINGLIHITGGNSNLFLMNPAGILFGANAQLNVMGDFTATTATGIGLGESWFNGVGDNNYAALVGTPSAFNFSVSQPGSIVNLGDLSLQPGQNLTLLGGNVLNSGTLSSSGGTITLAAVPGESLVRISQAGHLLSLEVRSPESTPTSLMPVSLPELLTGGGTTHANQVQVNPDGTVALTSSGPAVPIAGGTAIASGTLDVSGETGGTVQVLGENVGAIAAEINASGIQEGGTILLGGEYQGQGPIPNALYTFVSGDSTIKADAGTVGDGGRVILWADDTTRFYGNITARGGAEGGDGGFVEVSGKQDLIFRGIADLSATNGNLGTLLLDPENIIIVNGSDGADDYTFSEDGELWSSSSGDATISEEALENQTGNIYLTATNDITVENLTDNELSLKPKGGEVQLIADSDGDGTGSFSMHPSDTLSIQGGNLQISAAEISISNIELLTYEELLPCTYYCNYYDYNNYDGSNGYDSPQGYYQVHTPSNLDLYATGDILINTISTPDHNSGTVYIQSQQGMVEVGSILNSSSTFNLQGKTAVTTGEIHASSLSITSASGPVTVDGNITSRNGTTITAQSDIRTADIGSVNNRIFLTSNNGTITVGTLDTSSDWVPGKDIELRAAGNITTSALRTFSTANSTTYGSGGTISLTSTLGAIATREINTSSANQTAGNVTLRARNNIGTNNITTVGQTGGGSIVLNSSAGELNFGWLDSHSDGGRGGNINLFAAQGEIWTTVLRSYGYTQGGSIQITSNNGPTTLYENVYTHSVNGQGGNLTVTAEGDIISYYDIRTAGKTGSGDISLTSTSGAIDIIDTSSIQSYSETGTSGNVTLSALGNITTAEILSYGSIAGGDISITSNNGTINTTAGNIQAFSQEIGGNITLSALGEVKTGNIYAAAHESGGTVQITSQAGAIDTRAGEIRTNSKHGVGGSITLDASGDVLTSYIQASGQTGGGDVTLTSRTGAIDTSSNSIVATSEEGAGGDVTLTAEGDIETYDILAGAEGQGGNITLTSESGVIDASNAVLGSVSVSNNGGNVTLQADRNIYTNSIQTHTEGDATKRGGDIRITSTSGAIDTTGGGNLIVPEPQISLDASIAEIANTFSTEKANLNAYAANGTGGNITLSAPNGLTLGHLSSFGPANSGSVSVTSLLGDITTQVIFSVSENGTGGNITLNAPQGDITTSHLASYAAQQGGTINLTSGGRFNIGGATINSYATTGAAGDVTIALQESLTLGGDSNRSAIRSEGYTSGGKITVTSDTGAIAANGSLDSFSSEGTAGNVILSGNGDITPNGIRSEGAQQGGSITLESTTGTIDTRNGGLNSYSNAGTAGDVNLTASGDVSTSTIRSEGYTQGGKITITSDSGAIATDGPLNSFSQTGTAGTVNLSALQNNITASNIRSEGQQGGGSITIHTGGTLDLSAATLNSYSSTGTAGDVTLTAEQNINLGGDESNSAIRSEGYTQGGKITITSDSGAIATGGSLDSFSSQGTAGNVTLSADGDITPNGIRSEGTQQGGSITLESITGNLDTRNGGLNSYSSAGTAGDVNLTASGDVTTSTIRSEGYTQGGNIGINSNSGAIATTDSLNSFSETGTAGTVNLSANQNITTNGIRSEGSQQGGNITLESATGGVDASGGNLDSYSSDGNAGQITVTAEGDIQTGFIRSFTLDDSSTSLGGEIRLTSRSGAIDTTAGDLSGEAEIALDADVSSPEVANAFQHDQANINAYSANGTAGNITLNANNQITTRHISSYAGEGSGNVTLGNSIGDITTGVIFSSTRNGNGGAIAIQAPDGNININHIATYSTNGTGGEVNLSASGSVTLNNIASFGNLESGDVTITSDASTITTGAIQTLAPSGTSGNITLNTFSTSGNIQTAQLRSSGAEGAGDITVIAEDGSVLSGDIESTSENGDSGDITVEGSGDVETGDIQSEGGQNSGDITVNSSEGSATTGNVETIAHNGDSGNIAVNAEKDVLTGDIRSEASQNSGNIRCQ
>NC_019693.1|WP_083896801.1|4988232_4990326_+|CHAT-domain-containing-protein
MGILAILPSMLKKMYSPETFGPKPVKIVATFDVNSNSGRVTTGNIETIAHNGNSGNISVTAEKDILTGDIRSIGGNNSGNIQVESRWGTITTGDIESIAGTGTAGDISLYADGEINTGNVTSTGALGGGNIDLNSKTGEVNTGTVLTNGEQLDISEGSAIAPTEEPDAFVVPWIEQSNLLPQTLETQQAGNPNATQELNPVLTVDPGINIAQQNLEMQQVLSRTGDSLAITSMVNSDRIGLQGLQNNSTLNSMMQAIGISDLKSVTDSISDRTSTTQQILQALNAFHSSPLGISSGDAVAALEQSRDDEYSEYFGTNFSQRLMNSASLKDALVKITAETGYQFAVIYITALPSQLELILFTADGQPIRKTIPEAPREQLLEVVNQFRGELTNPRRFNSQSYLKSSQQLYNWLIAPIAADLEAAGINTLMFSMDAGLRSLPIAALHDGEQFLVEKYSLSQIPSVSLIDTTYRALQDTRVLAMGASTFTELSPLPAVPVELTTIASRLWQGEAFINEQFTRENLLQQRQSYPYPIIHLATHGEFKSGSPSESYIQLWDDQLQLDRIREMGWNSPVVELLVLSACRTALGDERAELGFAGLAVQAGVKSALASLWYVSDEGTLALMTEFYTHLTDAKIKAEALREAQIAMIRGEVRIEGGQLLGTGNLEGITLPSGLQNQRLSFAHPYFWSSFTLIGSPW
>NC_019693.1|WP_156824055.1|4990634_4992380_-|group-II-intron-reverse-transcriptase/maturase
MNKVNTSLKTTETWNAIPWAKVQRKVFKLQKRIFQAAKSGQDAKARRLQKLLTSSYYARLLAVRKVTQDNQGKRTAGIDGVKSLKPEQRLELVKDLGEQFLAKALRRVWIPKPGRNEKRPLGIPTIRDRAEQALVKQALEPEWEARFEGTSYGFRPGRSAHDAIGRIYASINKGSYYVLDADITKCFDKINHEYLLSKLDCCSQHRRQIKQWLKAGVVDNGVFEETPSGTPQGGVISPLLANIALDGMARLIEELYPLIQGQKVKATLIRYADDFVVISPEIEIINQCKIALENWLKPVGLELKPEKTKICHTLREIEVNGEKVTPGFDFLGFTIRQYPVGKYKSGKTGGANSRLIGHKTHIKPSAKAIKAHSEALKGVIKNHKTAPQAALISRLNPIIRGWSNYYSGVVSAETFSQMDYNIWQQLRAWTVSRCGQANLEKLRKYFHKVTVKIGNGKERNEKWLFQAKDGLSLWKHSYTQITRHTLVKPEASPYDGNWSYWATRRGTSLEVPMRVAKLLKKHSGRCSRCGQYFAMEDLMEVDHIQPLSMGGKDEYRNLQLLHRHCHDKKTAEDMQNVKSYQ
>NC_019693.1|WP_015150102.1|4993361_4994801_+|phosphoglucomutase/phosphomannomutase-family-protein
MSAAGTSEEIVFGTDGWRGIIARDFTFANVRKVTRAIAAYLETAYSKDKPVLIAYDPRFLADQFSRTAAEVLVDLGWTVKMTDRDCPTPVIAYNARHLNTAGALMFTASHNPAPYCGIKYIPDYAGPATPEITDTIVANIAKTSDEPPSGKNTDKISIFDPKPAYLEFLYTLLDVDTIRKAKLKVKYDALYSTSRGYLDLVLDHCGCETESFHTWRDVLFGGGMPEPKGEMLVELVEAVKKDNADLGLATDGDADRFGIVDEKGNVLTPNTILLLLAKHLLQNKGKKGAIVRTVATTHLLDNLAEKYGLTLYETAVGFKYVGEKMRETDVLIGGEESGGLSILGHIPEKDGILADMLVAEAIAFAGKPLSQLVEEVIAEAGGPLYNNRLDLHLTEAHKSAVLDAYLKNPPTEVAGIKVKEVGRKDGIKLYLEDGGWILLRPSGTEPLIRVYMETNSPEKLQKVGQEMQAKIDKLAPVAA

Crispr_ID: NC_019693_50

• CRISPR_ID: NC_019693_50
• CRISPR_location: 5101238-5101324
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_50

Consensus_repeat	Method
GCGGTAAGCGGAGCTATCCCGTAGGGAATCG	CRISPRCasFinder

spacers of NC_019693_50

>50.1|5101269|25|NC_019693|CRISPRCasFinder
CCTTCTTATGAGTGACGCGCAAGAG

CRISPR arrays and Neighbor proteins around NC_019693_50

CRISPR arrays

The CRISPR arrays of NC_019693_50

>merge|NC_019693|50|5101238-5101324|CRISPRCasFinder
GCGGTAAGCGGAGCTATCCCGTAGGGAATCGCCTTCTTATGAGTGACGCGCAAGAGGCGGTAAGCGGAGCTATCCCGTAGGGAATCG

>NC_019693|50|49|5101238-5101324|CRISPRCasFinder
GCGGTAAGCGGAGCTATCCCGTAGGGAATCG	CCTTCTTATGAGTGACGCGCAAGAG
GCGGTAAGCGGAGCTATCCCGTAGGGAATCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015150167.1|5102796_5103021_+|DUF2811-domain-containing-protein	unknown	unknown	gnl|CDD|371302
NC_019693.1|WP_015150164.1|5097918_5098827_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823908.1|5101072_5101231_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156824079.1|5091931_5092762_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|223533
NC_019693.1|WP_015150173.1|5112108_5113968_+|NAD(P)H-quinone-oxidoreductase-subunit-F	unknown	unknown	gnl|CDD|236008
NC_019693.1|WP_044197547.1|5101624_5101813_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150162.1|5096604_5097180_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_019693.1|WP_156824080.1|5092909_5093272_+|Dabb-family-protein	unknown	unknown	gnl|CDD|214884
NC_019693.1|WP_015150172.1|5109552_5111061_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150160.1|5093720_5095448_-|succinate-dehydrogenase/fumarate-reductase-flavoprotein-subunit	unknown	unknown	gnl|CDD|180319
NC_019693.1|WP_015150157.1|5090105_5091140_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823910.1|5107657_5108167_+|DUF2141-domain-containing-protein	unknown	unknown	gnl|CDD|378303
NC_019693.1|WP_015150171.1|5108283_5109285_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|223533
NC_019693.1|WP_015150165.1|5099021_5101028_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_019693.1|WP_015150174.1|5114126_5114852_+|carbonic-anhydrase	unknown	unknown	gnl|CDD|239473
NC_019693.1|WP_015150169.1|5105807_5107019_+|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl|CDD|223715
NC_019693.1|WP_015150161.1|5095656_5095971_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150168.1|5103419_5104142_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_019693.1|WP_015150163.1|5097465_5097816_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823909.1|5102275_5102497_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015150167.1|5102796_5103021_+|DUF2811-domain-containing-protein	gnl|CDD|371302	pfam10929, DUF2811, Protein of unknown function (DUF2811). This is a bacterial family of uncharacterized proteins.	1.07079e-29
NC_019693.1|WP_156824079.1|5091931_5092762_+|tetratricopeptide-repeat-protein	gnl|CDD|223533	COG0457, NrfG, FOG: TPR repeat [General function prediction only].	2.64158e-10
NC_019693.1|WP_015150173.1|5112108_5113968_+|NAD(P)H-quinone-oxidoreductase-subunit-F	gnl|CDD|236008	PRK07390, PRK07390, NAD(P)H-quinone oxidoreductase subunit F; Validated.	0
NC_019693.1|WP_015150162.1|5096604_5097180_+|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	3.43085e-13
NC_019693.1|WP_156824080.1|5092909_5093272_+|Dabb-family-protein	gnl|CDD|214884	smart00886, Dabb, Stress responsive A/B Barrel Domain. The function of this domain is unknown, but it is upregulated in response to salt stress in Populus balsamifera (balsam poplar). It is also found at the C-terminus of a fructose 1,6-bisphosphate aldolase from Hydrogenophilus thermoluteolus.It is found in the pA01 plasmid, which encodes genes for molybdopterin uptake and degradation of plant alkaloid nicotine. The structure of one has been solved and the domain forms an alpha-beta barrel dimer. Although there is a clear duplication within the domain it is not obviously detectable in the sequence.	1.46526e-18
NC_019693.1|WP_015150165.1|5099021_5101028_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.3518e-52
NC_019693.1|WP_156823910.1|5107657_5108167_+|DUF2141-domain-containing-protein	gnl|CDD|378303	pfam09912, DUF2141, Uncharacterized protein conserved in bacteria (DUF2141). This domain, found in various hypothetical prokaryotic proteins, has no known function.	2.43944e-48
NC_019693.1|WP_015150171.1|5108283_5109285_+|tetratricopeptide-repeat-protein	gnl|CDD|223533	COG0457, NrfG, FOG: TPR repeat [General function prediction only].	4.20054e-25
NC_019693.1|WP_015150160.1|5093720_5095448_-|succinate-dehydrogenase/fumarate-reductase-flavoprotein-subunit	gnl|CDD|180319	PRK05945, sdhA, succinate dehydrogenase/fumarate reductase flavoprotein subunit.	0
NC_019693.1|WP_015150174.1|5114126_5114852_+|carbonic-anhydrase	gnl|CDD|239473	cd03378, beta_CA_cladeC, Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.	7.44107e-75
NC_019693.1|WP_015150169.1|5105807_5107019_+|hybrid-sensor-histidine-kinase/response-regulator	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.69519e-44
NC_019693.1|WP_015150168.1|5103419_5104142_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.19939e-89

Protein sequences

>NC_019693.1|WP_156823908.1|5101072_5101231_-|hypothetical-protein
MEPGANLFLRDESDRLLTTDTLHPLLLPNVAIATSGGPHPNPPLAKGRGPEV
>NC_019693.1|WP_015150165.1|5099021_5101028_+|serine/threonine-protein-kinase
MMAEKVVKTWLKQLSQRVAVNKAPLGLEETGDSGNGSLFSRFKGKDNPSQNPNGSSPTVTPGSNLQQFPDCSSHGYQVLQSLGHNYAGGRSTYLATHLKTQKPVVIKQFQFAKPGADWSAYKAHEREIKVLQGLSHPGIPRYLDSFETSEGFCLVHDYKNAQSLAVFRRLDPEKIKQIALAVLEILVYLQNRVPGVIHRDIKPENILMGDRSDIIYLIDFGFARIGGGEVAQSSVVSGTPGFMPPEQLLNLKLTEASDLYGLGVTLICLLTQTDSSEINRLIDSSYRLNFAELVPHLSDEFIHWLQKMVEPNSSDRFSHAAAALEALTPISVSRLLPEAEFSQTRLELRTQAGETLTQTLTVKNPVENTVLAGRWEIAPDSNNPKTKPDWISIKPAKFQGNETEFEIKIDTTNLVISQDYTRNLLLHANTANKTQIIPLSLSVSPREVPTELVGPEPGKIATWKQKIAVPFPVILFGTTVAVPLIFLSPYVAVAIAVPLVLLSGRGFADKIQDPAIEQVAEFSRKWLVAPSLVGLGLWSFTLVDIAWLEHPERKVLGVIVAAMAMGGIGIGVLELFKAGFKRMVVLLPLLIFGLSFVAIGMATGMAGKLAEVGVTGLVLSSTIKQEIQRKNYGIGAIARHLAVATLGIGVGTGLSWLLVHYGLAAGMW
>NC_019693.1|WP_015150164.1|5097918_5098827_-|hypothetical-protein
MIFDDFLSLEDVKTYNTEQILQKLNELGITLTKEEFLQQIQSCYGVSELKQKWKSLYEISAQGRDKDFVSLGALVLWERLAPNYFSSDQLYVAIEEGLDDLEAGERRKICELWLECWEKLKERFIPMGLSFADLDKKLDGCLYRVSEWLLEIPTELDKLGKEDPIYFQKEIDYCRDFLGTFPDADDRAIIQLTMLEAMTLFSLEKVEEGDNCFENLVKRYPGKDFLYITWGGLHWKTDFCPPSRVDLDKAEQIYRMGLTNLGDDYKMLLPDLKAVDKERLKAKKKSRSETKQKGKGKKSTRK
>NC_019693.1|WP_015150163.1|5097465_5097816_+|hypothetical-protein
MMKPLQKTIATTVGLSLLFWSTPSLASQNLRLTWVRMNATNRDGCVRQAVEAMKSSGLDNVEVQDGELVQGDTRDLEAKIMCIESGRELVAAIAVASDSSSDARDIRGRLRNYMRR
>NC_019693.1|WP_015150162.1|5096604_5097180_+|tetratricopeptide-repeat-protein
MPEELFHELPEINPTNSNRHQSLLHQKDSLSTEDQEGGQNYEYWKREGDRLRVAKAYLEAIGAYDSALLQKPTACYAWQQRGEVFKRLQRYEEAIASYRKALEVSVNPIARYQAWNGLGALFFTLERYEESIFAYKQALALCPNSMGSPHILEMEGIAWSRLNRYLEAHDCYDRAYHKAVEISDKTAKTSN
>NC_019693.1|WP_015150161.1|5095656_5095971_-|hypothetical-protein
MNNLKKYRLVCTLTFGDIYGQIIIWLIVIFLSLASALALWSTARQIYALATVGLIVVLSLPFLLFAFVTTLLNHIELNPVEISAEPAESSSRTAPNSNPAQAAS
>NC_019693.1|WP_015150160.1|5093720_5095448_-|succinate-dehydrogenase/fumarate-reductase-flavoprotein-subunit
MIEHDVIIVGGGLAGCRAAVEIGRINPSIDVAVVAKTHPIRSHSVAAQGGIAATLKNVDSTDSWEAHAFDTVKGSDYLADQDAVELLTKEAPDVVIDLEHMGVLFSRLPDGRIAQRAFGGHSHNRTCYAADKTGHAMLHELVNNLRRYGVQVYEEWYVMRLILEEGQAKGLLMYHILDGRLEVVRAKVVMFATGGYGRVFNTTSNDFASTGDGLAMSAMAGVPLQDMEFVQFHPTGLYPVGVLISEAVRGEGAYLINSEGDRFMATYAPSRMELAPRDITSRAITREIRAGRGVYPDGRPGGPCVFLDLRHMGQEKIMSRIPFCWEEAHRLLGVDAVYEPMPVRPTGHYSMGGIPVNTEGQVRSGPDGFVEGFFAAGECACVSVHGANRLGSNSLLECVVYGKITGAAIARYVENRKLPDLDDRPYLQQAQQELQSLVDRAGTLRIGAVRQGFQDAMSDHCGVFRNDELMREGLNQLGQYQQQYQQIYLDDKGKLWNTEIIEALELRSLMVVGQLILASALNRQESRGAHFREDYPDRDDEKFLKHTLSYYSPAGVDIRYRPVTITQFQPKERKY
>NC_019693.1|WP_156824080.1|5092909_5093272_+|Dabb-family-protein
MNPTVAIASNPEPPSPSEPPVHHIVLIKLQPDVTPEEIEQTIEDNRRLISAIPGVLEVSLGPKARDDREVHLKDYDLGLYVKLSNNADLDIYGPHPNHQEFLARNRSKIANIRVIDFYGE
>NC_019693.1|WP_156824079.1|5091931_5092762_+|tetratricopeptide-repeat-protein
MDATQANSSNRVATPTTTTNSTTNSPQGELEAQARGYELVVQREPNNETALRGLLETRLKLQDIPGAIAALEQLVAINPERTDYAVLLAQGKQQIGDRDGASTVYRSILETQPGNINALQGYVNLLLMESRPEAAIGLLEDTLKTAPQANQIQPGSIDVVSVQVILGQVYADQLRYDEAIAVYDEAMKAEPEDFRPIYAKAIVWQNQGKMAEAKPLFETAAQLAPPQYRDQIQQQAQQVAPAVPATPQPEAAPAAPAPAPAPEVDSTAEPAEPEAE
>NC_019693.1|WP_015150157.1|5090105_5091140_-|hypothetical-protein
MNSSPNQIPSSANTSETGQPDPSVQAQEPNPSVSPPAKSREPKPMAESQEVPDREAAPHDANGTVMRPHPIPLPSEPKQYRAIGLVSGRYQPSEEQFTRGNLITPEGTAIDAVLLGKVMSLVKNHLSDEENHLWVVYPRTRQKEKTLHVQIMGVWEPEKLTQASSDSTAQTTEATAPVPDESTAQTTEATAPVTEESSSPEDPGEIDIQDGYFSIRGEVIFQSQDEEYIVVKIKQSPKDADTKPKFFKLQLEGTLPGKAVGHFWDLHVKRQENALRIEQGNDMGSIAPKKKKPFKGKGGKPGGSKRPYKSSGRPVPNPTVQQTAAPRTEPLPKPVKRNKPPNQE
>NC_019693.1|WP_044197547.1|5101624_5101813_-|hypothetical-protein
MPTSPREIIWQEPEPNTWVQLLEQPSEYSADQALLLCKCGDREWVAWVPEHGEVILHEGQFY
>NC_019693.1|WP_156823909.1|5102275_5102497_-|hypothetical-protein
MGDFLLHNFTEFPPPIAFSHFLALIPSSTKTRELEGDRLGKTLLNLWKTPDNLWKSLWNLWGKPAEKIRIAKF
>NC_019693.1|WP_015150167.1|5102796_5103021_+|DUF2811-domain-containing-protein
MNANVSILAEIPEELHQSLKGYLDSHPDWDQDRVFAAALSLFLLQNGDNRTPEASKNYHQAARVYLETLFQHPV
>NC_019693.1|WP_015150168.1|5103419_5104142_-|response-regulator-transcription-factor
MASAKILVVDDDPAIRNLIHRFLSKQDYQMESAEDGKKALELFEQFNPDLVILDVNLPDTTGYQLCQAMQKRTGVFVLMLTSRTDEADKIRGFNLGADDYITKPFSLVELGARVGALLKRQRVVQVAEQPSVDFGSMSIDPVRREVTISARPIVLTALEFDLLYFLASHPGRVWRRSELLQEVWDYDYVGDQRVVDVHIGQIRRKIEGDGIYPKLIHTVRGVGYKFEAQSGDSDDTSEKL
>NC_019693.1|WP_015150169.1|5105807_5107019_+|hybrid-sensor-histidine-kinase/response-regulator
MNSNDSPNNSPLILLVDDDRTTRMLLRRAMHNEGYRVVEAADGIEGLELYKQHKPDMVLLDAKMPGMDGFTCCTQINAIAGGLGIPVLMITSLEDEDSVDRAFEAGATDYITKPIHWAVLRRRVQRLLQEKQAEREILKALDQERELNELRSRIVTMVSHEYRTPLTAILSSAELLECYWHKWDEQKRLKHLERIQLAATHLTQLVADVLSINEVESGQIEFNPAPVNLERLCQEAIAHLRLSPASPHQITLTHHGDDCDVILDGKLVQQMLISLLSNSIKYSPKGGNIDIELIFYNPDSLPENPGFSLTEAELNNIESPVTIFRVKDQGFGILPHEQGKIFNAFHRGSNVGTIQGTGLGLAIAKKCVELHRGEISIASEVGVGTTVTVTLPSRTSALPLNPG
>NC_019693.1|WP_156823910.1|5107657_5108167_+|DUF2141-domain-containing-protein
MSGTCINIFINWIKMMKTPGKIFLAIASIFSSLTLIQTVRAVPASQLNLEIEGITNPRGNICFTIFSRSDGFPRDGTKALKAECSPIENLPVTLSIDGLNAGNYAVAVFHDENADGQLNTNAVGIPQEGFGFSNNPPILTGAPKFSEATFFVAGQTTTVRITMKYLLRI
>NC_019693.1|WP_015150171.1|5108283_5109285_+|tetratricopeptide-repeat-protein
MQPMFKWLGIVTAIGISGISMPLPGLAIPDDPTGGMDSGQVTTSPDILEPLQPPVTPRATPQTPPQTPASTPRATPESSPAPATPRVQQEPVQPRPAPQATSEVETLLSRGQFLLSSKQYEDALRTYDSALELNSNNADAWIGRGMVLEQLARYDDAIAAIDRATEINPNYSLAWLSRGMVLKQAERFEDALTAFDRALDGNGQWGDNRAADAALNRGSVLWQLDRRDDALASFDRALELDPQFALAWYNKATALLILGELEAAVSAYDSAINSNGQWGLSTGPASAWYNRGLALEQLERYEDAIASYDQALRITPNHTKARQQLARLRQQAQ
>NC_019693.1|WP_015150172.1|5109552_5111061_-|hypothetical-protein
MFSADQLQKKFSQPLDRAAIALIAVLTVAIALLLLGGDSTAPRVREFTWQNKQVSASDRAFIMTFSRPMDRQSVEDNLSIEPPVPGKISWAGRRMAYTVTQGVPYGMQFKLELSQARERFAQAGKEGTLIEPFVGEFKSRDRALVYIGVSPEERGQLILYNFSKSEKTILTPKEITVLDYKPYSEGDRLLFSAIDSFSPNRGVLEQRLFTVTTGIIPETQGRRSRRRDNSPGQIKRILGSDNYQNLNFDLSPDGETILVQRVNKQDPTQFGLWKIEEGKQPKPLENEPGGDFIITPDSQAVAIAQGQGLAILPLEPKAEPVDFLPQFGRVLSFSADGSAAAMVKFNTDYTRSLYLVTTTGVSKELRRIQGSFLSAQFGPQGKTLYCLLTKLVEGEIYKEEPYIAAINLETGDLQPLVLLPDQREVHISLAPDGLGLLFDQIVSVAPQGNQAPVDAVRTSSGEAIARSRLWLLPLDPSAPTNRPLDYKPEELPFEGLRPGWLP
>NC_019693.1|WP_015150173.1|5112108_5113968_+|NAD(P)H-quinone-oxidoreductase-subunit-F
MADLLLTTVWLVPGYSLLGGLLAGAWSPGTIRKTGPRPSGYINLVLTFLAFVHSLLALPATWNQPAQQLSWTWLDAAGLTLTVDLKISALTVGAMALVTGLNLLAQIFAVGYMEMDWGWGRFYAMLGVFEAGICALILCNSLFFSYVILEVLTLGTYLLVGLWFSQPLVVTGARDAFLTKRVGDLILLMGVVALLPLAGTWNFDELAQWAQTADVDPKIATLLGLALIAGPLGKCAQFPLHLWLDEAMEGPVPSTILRNSVVVATGAWVLIKLQPVLALSEIATTTAIYIGAVTAVGASAIAIAQIDIKRSLSYSVSAYMGLVFIAVGTGETQTALMLLLSHAVAMALLVTCTGGIIWNTITQDLTQYGGLWSRRPISGLAFLVGVAGLVALPPFGGFWSLLTMAENLWQTHPELVGVLVVVNGLTAFSVIREFGLIFGGEPKPMTVRSPEVHWPMVLPMVILMGVTLHIPLILMEWNLLPDWANLNVPVAGVLIGSTLVGGGSAAFIYMSSRISKPVKFGPQSVQDFFAYDFYTAKLYKLTIVFAVGFVSQIVFWFDRYIVDGLVNLVGLFTVFSGQSLKYNVSGQTQFYALTILFGVAVLGMLLAWPSLSKIILIFN
>NC_019693.1|WP_015150174.1|5114126_5114852_+|carbonic-anhydrase
MEKVIRSTQVSRRNLLKFVAVALGTSAVTATLSCASASINQRNQYREVPDNLSPDDALTFLMEGNQRFVSETRLNPNQTLGRITEVAQEQTPFAALLSCADSRVPVEIVFDRGFGDLFVVRQAGNLVTPEETGSLEFGTAVLGSKVIMVLGHQSCGAVEAAMKGGEFPGQIGSLVAAIAPALASLEGQTGEPVENAIKANVSWQVNQLKQSPVISELIAEGKLKVVGGYYKLGTGEVELLT

Crispr_ID: NC_019693_51

• CRISPR_ID: NC_019693_51
• CRISPR_location: 5109284-5109438
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_51

Consensus_repeat	Method
AATACGGAATCCGGTTTTTGAAGGTCTATAAAAAGACCCGCACCCTGAAGGGTGG	CRISPRCasFinder

spacers of NC_019693_51

>51.1|5109339|45|NC_019693|CRISPRCasFinder
GGCTACACAGACGAAGCCCGCCTGCGCGGGCTCAAGAAAATCGAC

CRISPR arrays and Neighbor proteins around NC_019693_51

CRISPR arrays

The CRISPR arrays of NC_019693_51

>merge|NC_019693|51|5109284-5109438|CRISPRCasFinder
AATACGGAATCCGGTTTTTGAAGGTCTATAAAAAGACCCGCACCCTGAAGGGTGGGGCTACACAGACGAAGCCCGCCTGCGCGGGCTCAAGAAAATCGACAATACAGAATCCGGTTTTTGAAGGTCTATAAAAAGACCCGCACCCTGAAGGGTGG

>NC_019693|51|50|5109284-5109438|CRISPRCasFinder
AATACGGAATCCGGTTTTTGAAGGTCTATAAAAAGACCCGCACCCTGAAGGGTGG	GGCTACACAGACGAAGCCCGCCTGCGCGGGCTCAAGAAAATCGAC
AATACAGAATCCGGTTTTTGAAGGTCTATAAAAAGACCCGCACCCTGAAGGGTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015150180.1|5121604_5122291_+|TIGR00266-family-protein	unknown	unknown	gnl|CDD|376704
NC_019693.1|WP_015150167.1|5102796_5103021_+|DUF2811-domain-containing-protein	unknown	unknown	gnl|CDD|371302
NC_019693.1|WP_015150164.1|5097918_5098827_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823908.1|5101072_5101231_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150173.1|5112108_5113968_+|NAD(P)H-quinone-oxidoreductase-subunit-F	unknown	unknown	gnl|CDD|236008
NC_019693.1|WP_015150174.1|5114126_5114852_+|carbonic-anhydrase	unknown	unknown	gnl|CDD|239473
NC_019693.1|WP_044197547.1|5101624_5101813_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150172.1|5109552_5111061_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150165.1|5099021_5101028_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_019693.1|WP_015150175.1|5114915_5116424_+|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl|CDD|180945
NC_019693.1|WP_156823910.1|5107657_5108167_+|DUF2141-domain-containing-protein	unknown	unknown	gnl|CDD|378303
NC_019693.1|WP_015150178.1|5118669_5120709_-|NACHT-domain-containing-protein	unknown	unknown	gnl|CDD|227922
NC_019693.1|WP_015150176.1|5116593_5117889_+|CO2-hydration-protein	unknown	unknown	gnl|CDD|370890
NC_019693.1|WP_015150168.1|5103419_5104142_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_019693.1|WP_015150177.1|5117971_5118373_-|fasciclin-domain-containing-protein	unknown	unknown	gnl|CDD|225214
NC_019693.1|WP_015150169.1|5105807_5107019_+|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl|CDD|223715
NC_019693.1|WP_015150179.1|5120916_5121579_+|TIGR00266-family-protein	unknown	unknown	gnl|CDD|272989
NC_019693.1|WP_015150163.1|5097465_5097816_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150181.1|5122327_5123065_+|TIGR00266-family-protein	unknown	unknown	gnl|CDD|376704
NC_019693.1|WP_156823909.1|5102275_5102497_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015150167.1|5102796_5103021_+|DUF2811-domain-containing-protein	gnl|CDD|371302	pfam10929, DUF2811, Protein of unknown function (DUF2811). This is a bacterial family of uncharacterized proteins.	1.07079e-29
NC_019693.1|WP_015150178.1|5118669_5120709_-|NACHT-domain-containing-protein	gnl|CDD|227922	COG5635, COG5635, Predicted NTPase (NACHT family) [Signal transduction mechanisms].	4.5157e-16
NC_019693.1|WP_015150180.1|5121604_5122291_+|TIGR00266-family-protein	gnl|CDD|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	2.5207e-69
NC_019693.1|WP_015150173.1|5112108_5113968_+|NAD(P)H-quinone-oxidoreductase-subunit-F	gnl|CDD|236008	PRK07390, PRK07390, NAD(P)H-quinone oxidoreductase subunit F; Validated.	0
NC_019693.1|WP_015150174.1|5114126_5114852_+|carbonic-anhydrase	gnl|CDD|239473	cd03378, beta_CA_cladeC, Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.	7.44107e-75
NC_019693.1|WP_015150165.1|5099021_5101028_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.3518e-52
NC_019693.1|WP_156823910.1|5107657_5108167_+|DUF2141-domain-containing-protein	gnl|CDD|378303	pfam09912, DUF2141, Uncharacterized protein conserved in bacteria (DUF2141). This domain, found in various hypothetical prokaryotic proteins, has no known function.	2.43944e-48
NC_019693.1|WP_015150168.1|5103419_5104142_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.19939e-89
NC_019693.1|WP_015150177.1|5117971_5118373_-|fasciclin-domain-containing-protein	gnl|CDD|225214	COG2335, COG2335, Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane].	3.11699e-56
NC_019693.1|WP_015150169.1|5105807_5107019_+|hybrid-sensor-histidine-kinase/response-regulator	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.69519e-44
NC_019693.1|WP_015150179.1|5120916_5121579_+|TIGR00266-family-protein	gnl|CDD|272989	TIGR00266, TIGR00266, TIGR00266 family protein. [Hypothetical proteins, Conserved].	7.07216e-66
NC_019693.1|WP_015150176.1|5116593_5117889_+|CO2-hydration-protein	gnl|CDD|370890	pfam10216, ChpXY, CO2 hydration protein (ChpXY). This small family of proteins includes paralogues ChpX and ChpY in Synechococcus sp. PCC7942 and other cyanobacteria, associated with distinct NAD(P)H dehydrogenase complexes. These proteins collectively enable light-dependent CO2 hydration and CO2 uptake; loss of both blocks growth at low CO2 concentrations.	0
NC_019693.1|WP_015150181.1|5122327_5123065_+|TIGR00266-family-protein	gnl|CDD|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	1.26843e-73
NC_019693.1|WP_015150175.1|5114915_5116424_+|NADH-quinone-oxidoreductase-subunit-M	gnl|CDD|180945	PRK07363, PRK07363, NADH-quinone oxidoreductase subunit M.	0

Protein sequences

>NC_019693.1|WP_156823910.1|5107657_5108167_+|DUF2141-domain-containing-protein
MSGTCINIFINWIKMMKTPGKIFLAIASIFSSLTLIQTVRAVPASQLNLEIEGITNPRGNICFTIFSRSDGFPRDGTKALKAECSPIENLPVTLSIDGLNAGNYAVAVFHDENADGQLNTNAVGIPQEGFGFSNNPPILTGAPKFSEATFFVAGQTTTVRITMKYLLRI
>NC_019693.1|WP_015150169.1|5105807_5107019_+|hybrid-sensor-histidine-kinase/response-regulator
MNSNDSPNNSPLILLVDDDRTTRMLLRRAMHNEGYRVVEAADGIEGLELYKQHKPDMVLLDAKMPGMDGFTCCTQINAIAGGLGIPVLMITSLEDEDSVDRAFEAGATDYITKPIHWAVLRRRVQRLLQEKQAEREILKALDQERELNELRSRIVTMVSHEYRTPLTAILSSAELLECYWHKWDEQKRLKHLERIQLAATHLTQLVADVLSINEVESGQIEFNPAPVNLERLCQEAIAHLRLSPASPHQITLTHHGDDCDVILDGKLVQQMLISLLSNSIKYSPKGGNIDIELIFYNPDSLPENPGFSLTEAELNNIESPVTIFRVKDQGFGILPHEQGKIFNAFHRGSNVGTIQGTGLGLAIAKKCVELHRGEISIASEVGVGTTVTVTLPSRTSALPLNPG
>NC_019693.1|WP_015150168.1|5103419_5104142_-|response-regulator-transcription-factor
MASAKILVVDDDPAIRNLIHRFLSKQDYQMESAEDGKKALELFEQFNPDLVILDVNLPDTTGYQLCQAMQKRTGVFVLMLTSRTDEADKIRGFNLGADDYITKPFSLVELGARVGALLKRQRVVQVAEQPSVDFGSMSIDPVRREVTISARPIVLTALEFDLLYFLASHPGRVWRRSELLQEVWDYDYVGDQRVVDVHIGQIRRKIEGDGIYPKLIHTVRGVGYKFEAQSGDSDDTSEKL
>NC_019693.1|WP_015150167.1|5102796_5103021_+|DUF2811-domain-containing-protein
MNANVSILAEIPEELHQSLKGYLDSHPDWDQDRVFAAALSLFLLQNGDNRTPEASKNYHQAARVYLETLFQHPV
>NC_019693.1|WP_156823909.1|5102275_5102497_-|hypothetical-protein
MGDFLLHNFTEFPPPIAFSHFLALIPSSTKTRELEGDRLGKTLLNLWKTPDNLWKSLWNLWGKPAEKIRIAKF
>NC_019693.1|WP_044197547.1|5101624_5101813_-|hypothetical-protein
MPTSPREIIWQEPEPNTWVQLLEQPSEYSADQALLLCKCGDREWVAWVPEHGEVILHEGQFY
>NC_019693.1|WP_156823908.1|5101072_5101231_-|hypothetical-protein
MEPGANLFLRDESDRLLTTDTLHPLLLPNVAIATSGGPHPNPPLAKGRGPEV
>NC_019693.1|WP_015150165.1|5099021_5101028_+|serine/threonine-protein-kinase
MMAEKVVKTWLKQLSQRVAVNKAPLGLEETGDSGNGSLFSRFKGKDNPSQNPNGSSPTVTPGSNLQQFPDCSSHGYQVLQSLGHNYAGGRSTYLATHLKTQKPVVIKQFQFAKPGADWSAYKAHEREIKVLQGLSHPGIPRYLDSFETSEGFCLVHDYKNAQSLAVFRRLDPEKIKQIALAVLEILVYLQNRVPGVIHRDIKPENILMGDRSDIIYLIDFGFARIGGGEVAQSSVVSGTPGFMPPEQLLNLKLTEASDLYGLGVTLICLLTQTDSSEINRLIDSSYRLNFAELVPHLSDEFIHWLQKMVEPNSSDRFSHAAAALEALTPISVSRLLPEAEFSQTRLELRTQAGETLTQTLTVKNPVENTVLAGRWEIAPDSNNPKTKPDWISIKPAKFQGNETEFEIKIDTTNLVISQDYTRNLLLHANTANKTQIIPLSLSVSPREVPTELVGPEPGKIATWKQKIAVPFPVILFGTTVAVPLIFLSPYVAVAIAVPLVLLSGRGFADKIQDPAIEQVAEFSRKWLVAPSLVGLGLWSFTLVDIAWLEHPERKVLGVIVAAMAMGGIGIGVLELFKAGFKRMVVLLPLLIFGLSFVAIGMATGMAGKLAEVGVTGLVLSSTIKQEIQRKNYGIGAIARHLAVATLGIGVGTGLSWLLVHYGLAAGMW
>NC_019693.1|WP_015150164.1|5097918_5098827_-|hypothetical-protein
MIFDDFLSLEDVKTYNTEQILQKLNELGITLTKEEFLQQIQSCYGVSELKQKWKSLYEISAQGRDKDFVSLGALVLWERLAPNYFSSDQLYVAIEEGLDDLEAGERRKICELWLECWEKLKERFIPMGLSFADLDKKLDGCLYRVSEWLLEIPTELDKLGKEDPIYFQKEIDYCRDFLGTFPDADDRAIIQLTMLEAMTLFSLEKVEEGDNCFENLVKRYPGKDFLYITWGGLHWKTDFCPPSRVDLDKAEQIYRMGLTNLGDDYKMLLPDLKAVDKERLKAKKKSRSETKQKGKGKKSTRK
>NC_019693.1|WP_015150163.1|5097465_5097816_+|hypothetical-protein
MMKPLQKTIATTVGLSLLFWSTPSLASQNLRLTWVRMNATNRDGCVRQAVEAMKSSGLDNVEVQDGELVQGDTRDLEAKIMCIESGRELVAAIAVASDSSSDARDIRGRLRNYMRR
>NC_019693.1|WP_015150172.1|5109552_5111061_-|hypothetical-protein
MFSADQLQKKFSQPLDRAAIALIAVLTVAIALLLLGGDSTAPRVREFTWQNKQVSASDRAFIMTFSRPMDRQSVEDNLSIEPPVPGKISWAGRRMAYTVTQGVPYGMQFKLELSQARERFAQAGKEGTLIEPFVGEFKSRDRALVYIGVSPEERGQLILYNFSKSEKTILTPKEITVLDYKPYSEGDRLLFSAIDSFSPNRGVLEQRLFTVTTGIIPETQGRRSRRRDNSPGQIKRILGSDNYQNLNFDLSPDGETILVQRVNKQDPTQFGLWKIEEGKQPKPLENEPGGDFIITPDSQAVAIAQGQGLAILPLEPKAEPVDFLPQFGRVLSFSADGSAAAMVKFNTDYTRSLYLVTTTGVSKELRRIQGSFLSAQFGPQGKTLYCLLTKLVEGEIYKEEPYIAAINLETGDLQPLVLLPDQREVHISLAPDGLGLLFDQIVSVAPQGNQAPVDAVRTSSGEAIARSRLWLLPLDPSAPTNRPLDYKPEELPFEGLRPGWLP
>NC_019693.1|WP_015150173.1|5112108_5113968_+|NAD(P)H-quinone-oxidoreductase-subunit-F
MADLLLTTVWLVPGYSLLGGLLAGAWSPGTIRKTGPRPSGYINLVLTFLAFVHSLLALPATWNQPAQQLSWTWLDAAGLTLTVDLKISALTVGAMALVTGLNLLAQIFAVGYMEMDWGWGRFYAMLGVFEAGICALILCNSLFFSYVILEVLTLGTYLLVGLWFSQPLVVTGARDAFLTKRVGDLILLMGVVALLPLAGTWNFDELAQWAQTADVDPKIATLLGLALIAGPLGKCAQFPLHLWLDEAMEGPVPSTILRNSVVVATGAWVLIKLQPVLALSEIATTTAIYIGAVTAVGASAIAIAQIDIKRSLSYSVSAYMGLVFIAVGTGETQTALMLLLSHAVAMALLVTCTGGIIWNTITQDLTQYGGLWSRRPISGLAFLVGVAGLVALPPFGGFWSLLTMAENLWQTHPELVGVLVVVNGLTAFSVIREFGLIFGGEPKPMTVRSPEVHWPMVLPMVILMGVTLHIPLILMEWNLLPDWANLNVPVAGVLIGSTLVGGGSAAFIYMSSRISKPVKFGPQSVQDFFAYDFYTAKLYKLTIVFAVGFVSQIVFWFDRYIVDGLVNLVGLFTVFSGQSLKYNVSGQTQFYALTILFGVAVLGMLLAWPSLSKIILIFN
>NC_019693.1|WP_015150174.1|5114126_5114852_+|carbonic-anhydrase
MEKVIRSTQVSRRNLLKFVAVALGTSAVTATLSCASASINQRNQYREVPDNLSPDDALTFLMEGNQRFVSETRLNPNQTLGRITEVAQEQTPFAALLSCADSRVPVEIVFDRGFGDLFVVRQAGNLVTPEETGSLEFGTAVLGSKVIMVLGHQSCGAVEAAMKGGEFPGQIGSLVAAIAPALASLEGQTGEPVENAIKANVSWQVNQLKQSPVISELIAEGKLKVVGGYYKLGTGEVELLT
>NC_019693.1|WP_015150175.1|5114915_5116424_+|NADH-quinone-oxidoreductase-subunit-M
MLSLLIGLPLVGAALIGFWPSKGSPTLFRNIALVVALGILAWTVAIATQFDLASPGVQFSENLPWIPQLGLSYKLGIDGLSFPLLALSAFLNCIAIYGRGETVERPRLYYPMIFLVNAGITGAFAAQNLLLFVLFYELELIPLYLLIGIWGGQKRGYAAMKFLIYTALSGILILAAFLGMAWLSGSSSFDIGSISTDNLSLTTQLILLSILLVGFGIKIPLVPLHTWLPDAYVEASPAVAILLGGILAKLGAYGLIRFGLQLFPETWAIVGPGLAIIGVVSVMYGAFSAIAQKDIKRMVAYSSIGHMGYILVAAAAGTPLSLLGAVAQMVSHGLILAILFYIVGIIEQKVGTRELDVLNGLMNPNRGLPLTSALLILGGMASAGIPGLVGFIAEFMVFQGSFSVFPIQTLLCIIASGLTAVYFAILINRTCFGKLDNQLAYYPKVLFAERVPALILAVTIFILGIQPAWLVRWSEPTTTAMVANIQPAHPAQIAQKLNNFAP
>NC_019693.1|WP_015150176.1|5116593_5117889_+|CO2-hydration-protein
MTTATSTQLPPSTHEFADIIHRLEAGGAMLPDSPENLKQIIGIYKAYAVPMDFYWRDLLYIAQEVFLEPFNFFKYFLPKEYLELHNHYAGEDADLRIWRGEATAHPELIAFIEKGELNQKIPRLFHHWFHDRINMEFAEACMRSMLWHGRDMGWGKFDAYLDSDEYKANADVAIKAYFQGNPVMLGLYKLFPEMFLEQVRQLSYYSNLGLFWEVMAPVFFEMSDLYDEGKLTSVPEAMNFLVNGIFAIAGRPIYHHAHIRGEVYEIIPKSKGFTWLYEAALPYVEAIFYRTAPFRGTKSYNAQAKQVPDEQKDFHYGILYADVFPVGTAGIPPTLLMQDMLHFLPPYLVDYYRQYCRGEDDMLIQLGISFQRSMYCVTSAVIQALRTALLYPLDDPNPKHLIANRRFFETQLDRFKRPEARLRDIQSQDYR
>NC_019693.1|WP_015150177.1|5117971_5118373_-|fasciclin-domain-containing-protein
MPDIVDIAVSNDSFKTLVAAVQAANLVETLKSPGPFTVFAPTDAAFAKLPPGTIQTLLQNIPQLARILTYHVVSGKLMQADLAKLESVTSVEGSPITLDCSSGFEVKNATVVMADVEADNGVIHVIDNVILMG
>NC_019693.1|WP_015150178.1|5118669_5120709_-|NACHT-domain-containing-protein
MPKISPAFILILTVLVNGFFCMAIAITAASPPSLGILLGVLTLGCGLLCALTCWLPGGRVEQGFWLFGVLPLIAAVSVYFLLVSESLNPAFQANLSAASVLLWALGTALPTVLILWQRWQGWQSSAIALREGLLAAVESEAIARQQQSLHYAVQRYLVREPLTEELPRLWDVEVKIGKHPRRKLAPEQGILEGLQVAAPKQAGVEVLNEVGVRADPETGVLEMGAIAGIVLILGAPGAGKTSTLLELAWDLCDRARQNELEPVPVVLDLAHWQEQTPLLTWIEEEVCYKYNVNRKLVRELLADDRLLPLLDGLDELDSTQQEHCLKEIAQSRRQNGQALPLVLSTRMDTYQHRETRLRLYAAVGVQPLKKQQIERYLLASRSRELWENLQTDPTLFRLAKTPLFLNLMTVAYEEILIHSWKRLKTRDERQRYVFNAYIRRQLSRDMEKPIYSRKTEPPAEQTKQWLRLLAGVMSQNNHRIFSPDSLPTLRLQPTWKQLQYPLVLLLLFILLYAGLFALIYGWEVGGIYGIFFAIIALSCGGIIALKAPDIELSTTSPRLLWQSAIVSVICCLLGFLSFQFIGAILSAVTPTGGWVMYLLSVLFFIGATAPIFGLICGLITAIPWMKHLLLRVILWRRGEIPWNYRRFLEYVSQRLFLQRVGWQQYRFIHDLLRDRLGES
>NC_019693.1|WP_015150179.1|5120916_5121579_+|TIGR00266-family-protein
MEYEIRYKPSFATLFVTLSPGESITAEPGAAISMDSRIAMKTQFSGGFFSGLLKKWFGGESLLVNVFRNPTTHPLEVVLSQATIGDMACIELTQSSICLQPGAYIAHTPGIKITLGWAGFASWFAREGLFKLKLTGTGRVFFGAYGGLTPKRINGEFIVDNGHLVAYEPTIKMGISMSGGLFSSISSREGFVNRLKGQGIIYLQSRSVEGLVQFLNPQFR
>NC_019693.1|WP_015150180.1|5121604_5122291_+|TIGR00266-family-protein
MNVNILHQPDCAIAHLILKPGEDIIAEAGCMIAMKGDMQVSTTLRRGKGGGILGGLKRTLAGESLFLSVFRASSTGGEIFLAPQMLGDIFHYQLRETGLIVQATSYLACSAQVILDIGVQGFKSLFSGESFFWLEFSGRGDLLLSSFGAIYEIFVEGEYIVDTGHIVAFEKSLTFEITKPPGSNWVSAWLSGEGFVCRFKGRGRLFCQTHSPQAFGQFIGSQLSPRIE
>NC_019693.1|WP_015150181.1|5122327_5123065_+|TIGR00266-family-protein
MSRPIAYEIEHSPSYASLRLDLQPDQTVLVEAGAMAAMDTCIKMKSKIQGGLLKGLSRMVSGESLFISEFTAERKAGQLFVSPAVPGDIQHYVLDGNSLFVQSSGFLASSPTVVIDSKFQGFKGFFSGESLFLIRATGEGDLWFNSYGAIIEIPIAGDYIVDTSYIVAFEDTLDYRVEVLGGLSFRGLKTGILGGEGLVCRFHGTGRLWIQSRSLFPFLNFLNPFRPVQSSSSSSSSASDSSGDD

Crispr_ID: NC_019693_52

• CRISPR_ID: NC_019693_52
• CRISPR_location: 5178004-5178085
• CRISPR_type: TypeV
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: Cas14c_CAS-V-F

Consensus repeat of NC_019693_52

Consensus_repeat	Method
AGGGGAGGGGACCGGAGGGGTATTTGAG	CRISPRCasFinder

spacers of NC_019693_52

>52.1|5178032|26|NC_019693|CRISPRCasFinder
CATAGAAAACTTACTCTTGTAAGGGG

CRISPR arrays and Neighbor proteins around NC_019693_52

CRISPR arrays

The CRISPR arrays of NC_019693_52

>merge|NC_019693|52|5178004-5178085|CRISPRCasFinder
AGGGGAGGGGACCGGAGGGGTATTTGAGCATAGAAAACTTACTCTTGTAAGGGGAGGGGAGGGGACCGGAGGGGTATTTGAG

>NC_019693|52|51|5178004-5178085|CRISPRCasFinder
AGGGGAGGGGACCGGAGGGGTATTTGAG	CATAGAAAACTTACTCTTGTAAGGGG
AGGGGAGGGGACCGGAGGGGTATTTGAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015150222.1|5181440_5183396_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|223562
NC_019693.1|WP_015150213.1|5157548_5158097_+|chemotaxis-signal-transduction-protein	unknown	unknown	gnl|CDD|238374
NC_019693.1|WP_015150220.1|5178629_5179061_-|hypothetical-protein	unknown	unknown	gnl|CDD|274350
NC_019693.1|WP_015150217.1|5169772_5171671_-|response-regulator	unknown	unknown	gnl|CDD|381147
NC_019693.1|WP_015150209.1|5150787_5152536_-|hypothetical-protein	unknown	unknown	gnl|CDD|224117
NC_019693.1|WP_015150225.1|5185426_5185849_+|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|223725
NC_019693.1|WP_044197565.1|5185906_5187031_-|RNA-methyltransferase	unknown	unknown	gnl|CDD|236981
NC_019693.1|WP_015150216.1|5168223_5169078_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150227.1|5187155_5189630_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|223715
NC_019693.1|WP_015150214.1|5159300_5162528_+|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|214599
NC_019693.1|WP_015150224.1|5184270_5184987_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150221.1|5179620_5180673_-|glycoside-hydrolase-family-104-protein	unknown	unknown	gnl|CDD|381598
NC_019693.1|WP_015150215.1|5163000_5167764_+|response-regulator	unknown	unknown	gnl|CDD|223716
NC_019693.1|WP_015150212.1|5157169_5157535_+|response-regulator	unknown	unknown	gnl|CDD|381164
NC_019693.1|WP_015150228.1|5190441_5192511_+|S9-family-peptidase	unknown	unknown	gnl|CDD|224422
NC_019693.1|WP_015150223.1|5183580_5184204_+|transcription-activator	unknown	unknown	gnl|CDD|381692
NC_019693.1|WP_015150219.1|5178095_5178455_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_052315773.1|5158135_5158582_-|transposase	Cas14c_CAS-V-F	-	gnl|CDD|284650
NC_019693.1|WP_015150218.1|5171667_5176869_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|274362
NC_019693.1|WP_015150211.1|5155015_5156293_+|response-regulator	unknown	unknown	gnl|CDD|381129

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_052315773.1|5158135_5158582_-|transposase	Cas14c_CAS-V-F	-	5.1e-12	39.8	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015150222.1|5181440_5183396_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl|CDD|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NC_019693.1|WP_015150213.1|5157548_5158097_+|chemotaxis-signal-transduction-protein	gnl|CDD|238374	cd00732, CheW, CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together with CheA and the methyl-accepting chemotaxis proteins (MCPs), which are involved in response modulation.	1.09506e-25
NC_019693.1|WP_015150220.1|5178629_5179061_-|hypothetical-protein	gnl|CDD|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	7.95062e-06
NC_019693.1|WP_015150217.1|5169772_5171671_-|response-regulator	gnl|CDD|381147	cd19920, REC_PA4781-like, phosphoacceptor receiver (REC) domain of cyclic di-GMP phosphodiesterase PA4781 and similar domains. Pseudomonas aeruginosa cyclic di-GMP phosphodiesterase PA4781 contains an N-terminal REC domain and a C-terminal catalytic HD-GYP domain, characteristics of RpfG family response regulators. PA4781 is involved in cyclic di-3',5'-GMP (c-di-GMP) hydrolysis/degradation in a two-step reaction via the linear intermediate pGpG to produce GMP. Its unphosphorylated REC domain prevents accessibility of c-di-GMP to the active site. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.74751e-54
NC_019693.1|WP_015150209.1|5150787_5152536_-|hypothetical-protein	gnl|CDD|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	9.44817e-13
NC_019693.1|WP_015150225.1|5185426_5185849_+|peptidylprolyl-isomerase	gnl|CDD|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	1.41593e-62
NC_019693.1|WP_044197565.1|5185906_5187031_-|RNA-methyltransferase	gnl|CDD|236981	PRK11783, rlmL, bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL.	7.28628e-155
NC_019693.1|WP_015150227.1|5187155_5189630_-|PAS-domain-S-box-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	4.78172e-46
NC_019693.1|WP_015150214.1|5159300_5162528_+|HAMP-domain-containing-protein	gnl|CDD|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	8.08603e-72
NC_019693.1|WP_015150215.1|5163000_5167764_+|response-regulator	gnl|CDD|223716	COG0643, CheA, Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms].	1.8463e-173
NC_019693.1|WP_015150211.1|5155015_5156293_+|response-regulator	gnl|CDD|381129	cd17602, REC_PatA-like, phosphoacceptor receiver (REC) domain of PatA and similar domains. Nostoc sp. (or Anabaena sp.) PatA is necessary for proper patterning of heterocysts along filaments. PatA contains phosphoacceptor REC domain at its C-terminus and an N-terminal PATAN (PatA N-terminus) domain, which was proposed in a bioinformatics study to mediate protein-protein interactions. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays. Some members of this group may have an inactive REC domain, lacking canonical metal-binding and active site residues.	5.98811e-44
NC_019693.1|WP_015150228.1|5190441_5192511_+|S9-family-peptidase	gnl|CDD|224422	COG1505, COG1505, Serine proteases of the peptidase family S9A [Amino acid transport and metabolism].	0
NC_019693.1|WP_015150223.1|5183580_5184204_+|transcription-activator	gnl|CDD|381692	cd19357, TenA_E_At3g16990-like, TenA_E proteins similar to Arabidopsis thaliana At3g16990. This family of TenA proteins belongs to the TenA_E class, and lacks the conserved active site Cys residue of the TenA_C class; most have a pair of structurally conserved Glu residues in the active site. TenA_C proteins (EC 3.5.99.2; aminopyrimidine aminohydrolase, also known as thiaminase II) catalyze the hydrolysis of the thiamin breakdown product 4-amino-5-amino-methyl-2-methylpyrimidine (amino-HMP) to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) in a thiamin salvage pathway; the role of TenA_E proteins is less clear. Members of this family include Arabidopsis thaliana At3g16990, Zea mays GRMZM2G080501, and Pyrococcus furiosus PF1337, among others. Arabidopsis thaliana TenA_E hydrolyzes amino-HMP to AMP, and the N-formyl derivative of amino-HMP to amino-HMP, but does not hydrolyze thiamin; nor does it have activity with other thiamine degradation products such as thiamine mono- or diphosphate, oxythiamine, oxothiamine, thiamine disulfide, desthiothiamine or thiochrome as substrates. Structural studies of P. furiosus PF1337 strongly support its enzymatic function in thiamine biosynthesis. It has also been suggested that TenA proteins act as transcriptional regulators based on changes in gene-expression patterns when TenA is overexpressed in Bacillus subtilis, however this effect may be indirect.	1.77218e-67
NC_019693.1|WP_015150221.1|5179620_5180673_-|glycoside-hydrolase-family-104-protein	gnl|CDD|381598	cd00736, lambda_lys-like, Bacteriophage lambda lysozyme and similar proteins. Lysozyme from bacteriophage lambda hydrolyzes the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc), as do other lysozymes. However, unlike other lysozymes, bacteriophage lambda does not produce a reducing end upon cleavage of the peptidoglycan, but rather uses the 6-OH of the same MurNAc residue to produce a 1,6-anhydromuramic acid terminal residue and is therefore a lytic transglycosylase. An identical 1,6-anhydro bond is formed in bacterial peptidoglycans by the action of the lytic transglycosylases of E. coli, though they differ structurally.	1.04789e-61
NC_019693.1|WP_052315773.1|5158135_5158582_-|transposase	gnl|CDD|284650	pfam07282, OrfB_Zn_ribbon, Putative transposase DNA-binding domain. This putative domain is found at the C-terminus of a large number of transposase proteins. This domain contains four conserved cysteines suggestive of a zinc binding domain. Given the need for transposases to bind DNA as well as the large number of DNA-binding zinc fingers we hypothesize this domain is DNA-binding.	1.49695e-10
NC_019693.1|WP_015150218.1|5171667_5176869_-|PAS-domain-S-box-protein	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	1.36695e-75
NC_019693.1|WP_015150212.1|5157169_5157535_+|response-regulator	gnl|CDD|381164	cd19937, REC_OmpR_BsPhoP-like, phosphoacceptor receiver (REC) domain of BsPhoP-like OmpR family response regulators. Bacillus subtilis PhoP (BsPhoP) is part of the PhoPR two-component system that participates in a signal transduction network that controls adaptation of the bacteria to phosphate deficiency by regulating (activating or repressing) genes of the Pho regulon upon phosphorylation by PhoR. When activated, PhoPR directs expression of phosphate scavenging enzymes, lowers synthesis of the phosphate-rich wall teichoic acid (WTA) and initiates synthesis of teichuronic acid, a non-phosphate containing replacement anionic polymer. Members of this subfamily belong to the OmpR family of DNA-binding response regulators, which are characterized by a REC domain and a winged helix-turn-helix (wHTH) DNA-binding output effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	2.89556e-41

Protein sequences

>NC_019693.1|WP_015150218.1|5171667_5176869_-|PAS-domain-S-box-protein
MNLGPIHIVEKNSLMIAPDTGVSEAVTLMSQQRVSCALVVDNHQLVGILTERDVVRMTAEAIDLNTVKVAAIMTPDPVRIVVSSALEIFSVLSTLRQHKIRHLPAIDESGNILGVITQNSIRKVLQPTDLLKFQKVYQVMSDRVIHLPQTAGLWEITQQMTQSQVSCIVIVEDTDEQETIPMGIITERDIVNFRALNLNLAEWVASQVMSTPLFPIKTGDSLWDAHQLMENNGIRRLVVVNEAGNLTGILTQTSLLEALDPIEMYRTLEVLQEQVNRRVIEVNQVNERLQEEITLREQELQERSRLEAELKAQNAQLQAEIGDRIRVEAALAQREREFRALVEHAPDLIWRFNREFRYLYANPSSESLFGIPSGEILGKTIEELGFPDAVLSQWIEVLQQASETGTEQTLECAVPRRDGVKWWFARIVPELGNNGEVESILAIVRDISDRKQTEQERLQLLDLEQTARAEAEAATNRVRNILESITDAFFSLDSNWRFTYINSQAQVLFQRSQEELLGQSLWVEFPEARHGRFYEEYHRVVTENISREFLEFYPPLNRWFEIHAYPAKDGISVYFEDVTEQIRAEASLKESEQFLRSIYEGVETAIFIVDVLTDGTFRYFDSNPTHERIWQISAEEMSGITPEQLLHQAVADEVMQRYQHCIETRERITYEEKLTLEGQESWWLTHLSPIFDSSDRIYRLIGTSFNITDRKQAEIALEQQLKREQLLNAIQERIRSSLNLEEVLTTAAHEVRQFLSNDRLLIYRVDPDGTGIVVTHSSDPLAPEINGNTFPQETFSQEERDRYAQGEIVAIADTELVKHLPCLAALIKTLKIKAKLVIPILKEQNLWGLLIAHHCQGPREWHPSEIESLRSIAGQLAIAVQQSTLFEQAKAELIERQKAEEALQTSQRFVQNIADTSPNLLYIYDILEQRNIYVNREIVEMLGYSDEEISNLGNNLLPALIHPDDLGKIPEHFQNLSQAQEGDVFELEYRMRTIQGEWRNVLVRETIFTRTKNGAVKQLLGTATDITKIKQSEAALRESAEREKAVASAVQRIRQSLDLGTIFAATTEELQGCLTCDIVAIYRFNPDYSGEFVSEAITSQRVSVLQRNRQSLHLSAQPASGENCQMQALINSCLEWQDTHLIQTKGDAFNRDENCLVVEDIYQRNFSPCYLARLEEFQVRAYIIVPIFCGSKLWGLLAAYESDRPRQWQPSDHKIVIQIGNQLGVALQQAELLEQTQKQSDALQKAAIAADAANQAKSEFLANMSHELRTPLNAILGFTQLMNRNSSLSPQHQEYLKIINQAGEHLLSLINDILEMSKIEAGRTVLNPTSFHLISLLRNLEAMLKVQAQSKGLELNFELDSNLPGMIMSDESKLRQVLINILGNAIKFTNSGRVTLRAQLEPDVNNNSLNKSPIFSETPSILGIEIADTGSGIAPEEMNHLFEPFSQTETGRKSQQGTGLGLPISRKFIQLMGGDIHVSSTVGVGTVFSFEIQIVPINETLEPPTPTPRQVIGLDCDQECYRILVVDDAVNNRRFLVTLLSEIGFEVLEAENGQEAIALWSSWDPHLICMDMQMPVLDGYQATQQIKASRKGQDTVIIALTASAFEEERKGILSCGCDDFLHKPFREEVLFEKISTHLGIRYRYAPEIPHSPQVLSSRPNLLNRDEIKSYLFQMPPNFVTELYQFASQGYDEGIFELLKFIPEESSPLAQTLRELTKNFDFELIIELTEQEEA
>NC_019693.1|WP_015150217.1|5169772_5171671_-|response-regulator
MNYALGELTTSRQSQNNRPNILVVDDTPDNVRLLSSVLTDNGYRVCKALKGDMALTVCKNAVPDLILLDVMMPGMDGYEVCKCLKQQETTRQIPVIFLSALNEVDDKVKAFEAGGVDYISKPFQEAEVLSRVQTHLKLRQLQINLQEKNLCLEQEITERQNAQRSLEVSEAKNMALVNAIPDVMFRIGEDGFFLDYRSPSLGCLDDIPESPGNQRGNPLQKSRDFTQNIFPISESLAADSSFVGKHIQEVLSDDLAIWIMHYVQQTLVTSKIQIGEYVQRDKNQERWVSYEVRFVKSGPSEVLAIARDISSRKQADAARLQAEAIMRHQKQKIEQALTELQDAQVQLVQNEKMVGLGQLVAGIAHEINNPVNFIYGNISHVQSAIADLVNLLETYQKEHPPNQTVREILEELDFDFLSKDLRKMTSSIAVGAERINQIVLSLRKFSLMDESGVKKVDIHENLDTALILLKHRFKITETHEIELIKDYGEIPQILCYPGELNQVFFNLLNNAIDVLSDILPDRLKVQEANPTAPKFVPSIWISTALTNSQTLLIRIKDNGPGINESGRSRLFDPFFTTKPVGKGRGLGLSISYQIVVQKHGGQLTCNSTPGEGAEFVIELPLVQSTADPVGLS
>NC_019693.1|WP_015150216.1|5168223_5169078_-|hypothetical-protein
MFNSTALLIEAFVDRLQEGYHRTYGGYKPDYAEILAWAGGMALENIANSDALYHNVEHTILVTLVGQEILRGKHIREGGVSCEDWLHFIISLLCHDIGYVKGVCRQDEDSKRLYATGRDGLKVPIPFGSTDASLTPYHVDRGKLFISERFGGHSLIDAEVIKRNIELTRFPVPADEDHKDTFNYAGMVRAADLIGQLSDPRYLQKIAALFYEFDETGANKKLNYSHPGDLRRNYPKFYWHGVFPFITQALAYLNLTQQGKQIVANLYANVFKIEHEDQQLSEVA
>NC_019693.1|WP_015150215.1|5163000_5167764_+|response-regulator
MQPEQRQRIMGYFIEETTEHLNTIEQGLQNLASAVQDPSALAELFRAAHSVKGGAGMLELTAIQQIAHKLEDEFKVLQLVPVEVDPQLESLFVRVFRGLQETVALIRVSGPLDEEKAAAICAEVQPAINQLHVHLAQLAEETESPSAFVTRKEPRPDIGGQHTRIQSPKNPGVEEYSAKQLIFKSDVSRLLQEMIHLFKQAENSRGRERMQEICRQWIRAGEQFDLKLWCHLIDQAATAIANPENTFRVLAPILIKEIQKAREQVLCGQAEAITVSPKLEGLLQPQPQPQKSLTPQILGESTHTDSKFNPMSNNSSNSDQNQRLFEGGDSHRKKNPDSQNNQTWGEEKRGGKPTYNSGPEVGAAELNTLADLFEGESSYFDENWEGEEVVEEANPGEGNRETLPPDPGEVLANANDFDDLLFEPPADERTQMGTSENNDEENLANLFGLEGFVEMDDSSISEKPQSPSGAVSRKSSNQKLDDLGELFEEVATEELKEPDDWEQMWDDEPLDAVSEIVPPEPEAEFSLEIDEDSEFKDLLDISGLESSRDPGKDPFVSEVATEIPIDEENFDDLFGETTEDQDFAPNLTASEDSVDWFDSDPSETLETEEDLLDLLELETVPSSSSPTPSEPVGKRKPAPTSPPSDEFWLDFEEPDSEPESDVLDALDGLFDDEPSPAIADLDLMEDSSLDSQLFDEELGAGDDNNDLFPESSGNLDGDEWDWDLDPNDSDDKEDTSDFYQNLESLFEEPTERSPTLDLNQIAQPSPGPSKKTQSNSGFSSSTESNLDFEALFGENEPLSPKSDLSKGMPVGISEPIRERLDLPPEPKLTQGADIFTELDYLLAMGPLKATFDELEILLNPLSSPKAGTTSTSTTPATVSATANSEKSLLRSRGSDVDPEKTDVDFDDMEKLLRASADIGSRDTGGRVAPRRGGFEQTMRVPVRQLDNLSNLVGELVVNRNSIEQNQERMRQFLDNLLHQVSQLTDVGQRMQDLYERSLLEISLLASRQNYHFMGGSRNTQKDQSHTGSDWSALEMDRFTPFHSLSQDILELIVRVRESASDIEFLVDETEQVTRQLRQVTTQLQEGLTRSRMVPFAQTADRLPRGVRDNAIKFGKQVELQVEGRETLIDKMILEQLSDPMTHLVNNALAHGVETPEERRKKGKPPVGRIVVRAFHQGNQTVISVSDDGAGIDSEKVKAKALQRGLISPEVAKIMTRLDVYDLLFMPGFSTRDKADDLAGRGVGMDVVRTSLSSIRGVVTIDSTLGKGTTFTIRLPLTLSISKALCCISDRARIAFPMDGVEDMIDVPRDRIKTQEDGQTFIPWRDTMLPFRHLRELLVYNRHLGRGVVYGANPEEDIISVVVLRSAGNFLALQVDQVLGEQEIVIKQLEGPVPKPVGVAGATVMGDGRIVAIADVLELLDLAAGRLRREGTGTLWEDALGNRIQPEPEQEAVIDPTVLIVDDSITVRELLSLTFNKAGYRVEQARDGQEAWEKMRSGLPCDLVFCDIEMPRMDGLELLSRMQKDPILTSLPIAMLTSRGADKHRQMAIQMGASGYFTKPYLEESLLEAAGRMLKGEKLVSLKMEAGV
>NC_019693.1|WP_015150214.1|5159300_5162528_+|HAMP-domain-containing-protein
MVSSTDYQQDYEQALTAYTEKNYEEAALIVNQLVANFPEDPSARLLAGHIYCYGLQMYDVALGQYEGVLSLTDDPAFIEGASQGIDYANQYATEGMQSSEYGYEADNEFQSAMPEDFESDFDSIQSEQDTALFELEAPAPSYEEEFWEEDNSALGLQDRAYNEALAINQIGSDDADLSMELDPVDPNLELESMEFDELAEFESGDLGGGSGTPEGGLLNPFTSEEAFEGIADEDPFAIDDEEILSEVQNNQWSDPLASELPDFLPRDDEMPDLVGEETGIRVSKQSPFDQGQDDLDLMDLATPFQEFEDAFAPEDEAEFDSNLDPLEDEEDTSYYSNNGSAIDSDFDLFDADDDFGNEFSEEDEDESPHQNGKGAGTSGIPYDIDEDFDFNAPSEEEETLLMGRQQLEQTQALNSISKASGPPYSQPKGLTQPNLEEDDDDDDYDSKTFVSEPTNGFNQADSYELEDFDDAFSGGNSFDSKPNGEDFPNSISNSSPLLQEEGVDFLGEFDDFEDFGNIPDNIPDFDLSEDTTGASTGGFGMGRMGPKASFQDIDDSYDIAEDTDGSIIRDDEIFRFAGSAEQVPVFTPPENTPVETVASAEPGIFGFLENASLVKKFLWIALISGGVSAIAAASVSFAFSSQRNWPQQLKDPMMALAAGGASILTCFGVGSASAKLIRRSIDDLHNQFDTMSQGNLSARATVYNEDEFGQLSAKFNQMGRIIYTTTSEAQRKAEEQEQSKEDLQRQVIRLLDDVEGAARGDLTVQAEVTADVLGAVADSFNLTIQNLREIVLQVKLAARQVTKGATDSESFARSLSSDALRQAEELAATLNSVQVMTDLIQRVADNAREAEEVAKSASATAKKGGEAVEQTVAGILEVRETVAETTRKVKRLAESTQEISKIVALIATIAGRTNLLALNASIEAARAGEAGRGFAIVADEVRQLADRSAKALKEIEQIVMQIQSETGGVMVAMEEGTQQVIEGTKRAEQAKRALENIIQVTNRIDVLVRSITADTVEQSQTSRSVAQVMQAVELTAQETSQEAQRVSGSLQNLVGVARDLLTSVERFRVETGERR
>NC_019693.1|WP_052315773.1|5158135_5158582_-|transposase
MRVAPLIKNHQGSAFLQGLEDLGKVFGVTTIAVPLQHLSQNSSNCGEFLKKSLSTRTHKCLICGFVLDTEGNADLKILQGIGCTGGPMVKVQWIWRHRPSASVGTSRKVSPGAESGKLSAEAGNSSGFRAQRRLTFGLGISLSYLQID
>NC_019693.1|WP_015150213.1|5157548_5158097_+|chemotaxis-signal-transduction-protein
MVGNPDFLTGIGLEQAPEFQELESPEGELHLRFFVPSGNEFALSATGIREVISQAPDRITLIPNVSSLLLGTLNVRGRVIWVADLGQFLGEPATLNTDRPEIPVIAVEDQDTILGLAVDQIVGMAWLDVEQVRLPTNVPDSMAPFLRGEWIIPPKEESKEEEEKILRLLDQVAIVRSARWAA
>NC_019693.1|WP_015150212.1|5157169_5157535_+|response-regulator
MSTVLVVEDSVTQREMISTLLKESGLNVTVASDGLEALERIQETCPDLVVLDIVMPRMNGYEVCRRLKADPKTKNVPVVMCSSKGEEFDRYWGMKQGADAYIAKPFQPTELVGTVKQLLRR
>NC_019693.1|WP_015150211.1|5155015_5156293_+|response-regulator
MQGNLNEIDIRSILQLIELGQRTGELFVEAYGINSGNTCGGRDNVRDSLVYRYPYRDKRSRSCDQSWFVFFSNGQIIYAANTDTSLSRLRDFLRRYNAETALDGITNLSISATNALEYGYLWALLENHILTPAQGRNIIQGMVRETLFDLLSLHQGSFIFEMGPALAPQLTTLEIAPLVTKIIKQVQEWKQFHPHIQSPNQCPVISDAAQMREALPENTFNNLNRWADGTTNLRQMSRYLNRDILTVARAIYPFVQLGLVQLFYPNSSLNGNGLDECDLDPGFKIPRVVCIEDDLTVGKTVEAILAQYGYEVTALMNPLKALSLVFHLKPDLILCDITMPELDGYEICAMLRHSSAFRQTPIVMLTGKDGFIDRVKARMVGATDYLTKPFGESELLTIVEKYIGPGDPDVPEPDRLLAEVIEAEL
>NC_019693.1|WP_015150209.1|5150787_5152536_-|hypothetical-protein
MLYLAEVQKQKSGFGLGSGKAELKLLACQRGEQSWAAVPGSETIPADDANNLNAGTLVLVDLSPNKQIKGNIEEAANRLVSILQGFSRGQEKIKTKEEEIEQWMQSLTYQSQELQRREMELQVREEEIAQLDSQREEIQGSSEEAQRIRDELQAKQQELDAALEKLQSEKQTMEAQVAQSQQSVQLDEGLATHVQELLDYLTQTTPPMASLGEQIAVVLEQISAQQAVLDEHWQRLEQHRSQAQVEEQEAEAKQQELGRLRQEWEQNQGDLAEAHSQLKLLEKTLSIQQNHGNTLDAQVKNQVLLREQLVQLSEMFEQVAVVQKVDVEALERMPIEELQGVAQNLQQDLDKIFQFVNGQEEELKLQRETIQELEQKLANSHDSERWNIQRNLTDEQEAYQMLDQTLVGQRRNLRERQETLTLHQAVLARRQGHGDATPIKQAQPMDPVLAQIDQQKQILDQQLAQIKQEIEQTRQSLDGVQGQVSDRANQMEGKRQAIEQLEAQLAQLRSSAAQLRGRVTTYEEMLQPLQDKLNELKAKLEEVSTLLTQGQETEGHQQQAVTQLRDLLMGLMNSQSAELAAS
>NC_019693.1|WP_015150219.1|5178095_5178455_-|hypothetical-protein
MTLKATPAQLHYLQHLENPFNQAAQRIHTLQRRAISAIVITLLLLILTYTLDVLSAWASIATSTALSTLCLLNIISTTLTLLTGIAGIGAAMTFVSYRAKVLRCGSPKEKTQGPLALQE
>NC_019693.1|WP_015150220.1|5178629_5179061_-|hypothetical-protein
MKGIYNIVTVLAISLGMGIAPPAIAENLSQPSVRESQGVIEVDSYDFVVLAEEALEVADYQNAIFHANRAIDIAPALGNAYLIRGQARAYQGEIQAAIADLEQAAQVYRQNNNQIGYLLALEYLRDLNAPSSPQALTLPDLSD
>NC_019693.1|WP_015150221.1|5179620_5180673_-|glycoside-hydrolase-family-104-protein
MNQDSLKTPIPPDCEVIQLWLQQQPPHQRRDRRLWVREFLAFVRKPLAAVTLVDVRAFAQTLAARRIPPEQAQARLFVLKSLFAYGYHQGQLPINIPLQHWPKVRVKRPSPSGSAILTGVLSNLKSTFRQRFGRGPRKPATLQKQAAFWGGVCLAGVALAIPAHFNSQAETTEEVTIPQPALQVRRQTVASLKAAHVQAFLDTIAWAEGTAGPNAYRMQFTGTQFSGFQDHPREIKCGSSYGSRLCSDAAGKYQFLSTTWDRMAKKIGASDFSPANQDRAAIALLDEYGVLEDIEAGAFAYAAIQLIPVWPSFQDVGNGDRTRAIARLERVYEQKLRKHSFEPAAFRIQN
>NC_019693.1|WP_015150222.1|5181440_5183396_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MSIFTLQSVKKDFGIKEILRDASFSLNPTDKVGLIGTNGSGKSTLLKMIARLEPVDGGQILVNSGVRIVYLPQQPDLDENRTVLEQVFADCGDRMNLVREYEDLSHKIARNPEDGPLMARLSEVMHQMESSGAWELETQAKIILTQLGIEDFDAQIGTLSGGYRKRIALAAALLSDPDVLLMDEPTNHLDAISVEWLQSYLNSFRGAILLITHDRYFLDRVTNRIIELDRGELYTYDGNYSYYLEKKALAEEAAASQERKHYGVLRRELEWLSRGPKARSTKQKARIGRAMDLQDKEFKQSLGKVEISTASRRIGKKAIELENVSKAYGDRTLIQDFSYKFSPDDRIGIIGKNGIGKSTLLDIITGRLAPDSGTVEIGSTIHIGYFDQHCDDLLDAADQNQRAIEYVKEEAELVQTADGLQITASQMLERFLFPPNQQYLPIHKLSGGEKRRLFLLRVLMSAPNILILDEPTNDLDVQTLSVLEDYLEDFNGCAIVVSHDRYFLDRTVNTIFALEEGGNLRQYPGNYTVYLDYQKAEAVEAARQATANQNEKKPDSQTATVDKSERVSWDKNRQRKLSSKEKREYQQLETKIAEMEAEKAATEKALYHAEPGAVTEVQKLHQKVQDLAHEIEVATERWMELAEIESASSSN
>NC_019693.1|WP_015150223.1|5183580_5184204_+|transcription-activator
MTITCQEILKNHQPLWQEATVHPFLEGCKQGTITPEQFNTWLVQDYQFVVEFTRMLARILSVAPLHHFDVLLGGLIALKDELNWFQVKAAERNLSLDVAKQRTCEEYSQFLANLARTPYAVQATGLWAVELAYNQGWQLPGPMPEPYTEFADRWGNPGFTDYVKLLEQQADEMLSNASPEVQKEAEQTVITVAQFEKAFWQMAFNAT
>NC_019693.1|WP_015150224.1|5184270_5184987_-|hypothetical-protein
MDSEQTQEILSLREKKLTPKQIARKMGLKVSDVTGFLKEQAEQAAIAREDSGELPPIVECLINANCVPRLFPPEDELVTQSEDDLENISDPGMAIVTVTRSPGFNRFIVCTYLVDYWCLGVKDASGPRKYNRSEYERITALYYDSFIGGSEKISLTQAQALVWGAVEYAEKLGLKPHHDFGKAKELLGEWDGELKIEFGQDGKPFYTSGPYDNSASIINSLNKSVGEGNYEYMIGMES
>NC_019693.1|WP_015150225.1|5185426_5185849_+|peptidylprolyl-isomerase
MPRAIMETDKGTIHLDLFDKDAPNTVDNFTKLSESGFYDGLTFHRVIPNFMIQGGCPNGTGTGGPGYKINCEINPNKHLAGTLSMAHAGRNTGGSQFFICHSPQPHLDGQHTVFGKTEDMDVVNSIRAGDKILSVKIEKD
>NC_019693.1|WP_044197565.1|5185906_5187031_-|RNA-methyltransferase
MTEYFATVARGLEPIAAQELERLGAQDVRPDFTGVHFSGDRALLYRVNLWGRTLFRVLVPIREFSCPNAEMLYREVQSIDWEEYLDPGHTLAVNCTGSNHKLNHTHFTALQVKNAIVDQQRDRTGERSTVDPKDPDLLLNLHIHGDRAILSLDSSGNSLHRRGYRPAMGTAPLKETLAAAILELAEYSPEQTFLDPLCGSGTLPLEAGLKALNIAPGLFRERFGFMSWRDFDLELWQDIRQEALDGQKAELTAPIFGSDRDRAVIQQAHLNAENCGLDAHVHFSIQEFYQIEPPAESGIFICNPPYGERLGEVHELGDFYKSMGDILKQRFTGWTAYILSGNKELTKKIGLKSSKRIPVYNGSLPCTLLKYELY
>NC_019693.1|WP_015150227.1|5187155_5189630_-|PAS-domain-S-box-protein
MAKILIVDDDVTVQLVLQDLLESDGHRITVASDGTEGLRLARELEPDLIVCDWMMPGLDGLEVCQKIKADSELAPMFFILLTAREEVGDRIKGLNTGADDFLSKPIETEEFLARVRAALRLHGLTQELSQANQQLEALVEVQRRLLAFKGDTTPDNSPSYPYTEILKPLGQAAHASRVYLCQNPPLSMGNSTPTGPSPLLVAQWNCEELKIQPGSDSNPQPAQCLSLKAPILIERWVSLLARGEVIADVVSNFPDSERELLEQSGIQSLLILPLIVHGEFFGFIRFDNCTEPRVWSESEVSILQAAAAAVSLHKERALAEVALRSSEARYRAIVEDQTELICRFAPDGTLTFVNDAYCRYFGVSRKELMDGSVVSLIPDIDRNPVAMPVVTRERRIMLTNGEVRWQQWTDRAIFDAQGVLSEFQAVGRDITEQKLAEAAVQASEERFRQLAENIEEVFWISDPNYSQILYVSPAYEEIWGLERQELYEKPTARLDAIHPDDRQAVLTGLMPLDRLDREYRIIRPDGSIRWIRDRGFPIRDEEGKIYRIAGISEDITEIKRAEEQLRHALAKEREIMEFRTRFVSMVSHEFRTPMTTILSSADLLEYYLEEWPNDKLDKKFQALHRIQSATVNMTQLLEDVLFIGRAEMSQLPFNPQSLDLVPFCKGIVEEFQFSSTKNYTINFVENYSEEFLSRKSRKPCFDEKLLRYILNNLLSNAIKYSPEGGEVYFELTCTDTDVTFMIKDSGIGIPSEEIPRLFQTFHRCGNVGNIPGTGLGLAMVKRSTDLHGGEISVKSEVGFGTAFTVRLPLYSRQREEDSSSQQVG
>NC_019693.1|WP_015150228.1|5190441_5192511_+|S9-family-peptidase
MSYFDGTLSYPKTRKGDLVDDYHGIQISDPYRWLEDPDAEETRAWVEAQNTVTFAYLNEIPQRDRLKHRLTELWDYEKYGIPFKKGSRYFYFKNDGLQNQSVLYVLNHLDDQPRVLLDPNKLSEDGTIALAGIAISENAQFMAYGLSSSGSDWQEWKVRDIETGEDLSDHLQWIKFSGASWTHDHQGFFYSRYDEPNTKGQYEDVNYYQKLFYHRLGTPQSDDILIYDRPDQKEWGFSGGVSEDGTVLIISVWRGSDPKNLVFYKDLTHPDASVIELITEFEAQYGFIDKEGDLFWFQTDLDAPRGRAISLNIRTGDRQELIPEAPETLESIGLLNNQFVADYLKDARSQIKLFNLDGSFIREVELPGIGSAGGFNGKRHDTETFYSFTSFTTPPTIYHYDMVTGESTVYRHPQVDFNPDDYTTEQIFYTSKDGTQVPMFIIHKQGIQRDGNNPTYLYGYGGFNISLTPSFSVSQVVWMELGGIIAIPNLRGGGEYGEDWHQGGTKLNKQNVFDDFIAAAEWLIEHGYTKSQKLAIAGGSNGGLLVGACMTQRPDLFAAALPAVGVMDMLRFHKFTIGWAWCSDYGSPDNPDEFKALYAYSPLHNLKPGTAYPATLITTADHDDRVVPAHSFKFAAALQAAHTSKAPVLIRIETKAGHGAGKPTAKIIEEVADKWAFLVRTLEMDIPVK

Crispr_ID: NC_019693_53

• CRISPR_ID: NC_019693_53
• CRISPR_location: 5181187-5181315
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: Cas14c_CAS-V-F

Consensus repeat of NC_019693_53

Consensus_repeat	Method
AGTTTCTGCAACGGATTGGTGGCGGATTGCCCGAGATTTTGTG	CRISPRCasFinder

spacers of NC_019693_53

>53.1|5181230|43|NC_019693|CRISPRCasFinder
AAAAAACCCGGTTTCTTGTCCTAGGCAGCACAATTAGAAACCG

CRISPR arrays and Neighbor proteins around NC_019693_53

CRISPR arrays

The CRISPR arrays of NC_019693_53

>merge|NC_019693|53|5181187-5181315|CRISPRCasFinder
AGTTTCTGCAACGGATTGGTGGCGGATTGCCCGAGATTTTGTGAAAAAACCCGGTTTCTTGTCCTAGGCAGCACAATTAGAAACCGAGTTTCTGCAACGGATTGGTGGCGAATTGCCCGAGATTTTGTG

>NC_019693|53|52|5181187-5181315|CRISPRCasFinder
AGTTTCTGCAACGGATTGGTGGCGGATTGCCCGAGATTTTGTG	AAAAAACCCGGTTTCTTGTCCTAGGCAGCACAATTAGAAACCG
AGTTTCTGCAACGGATTGGTGGCGAATTGCCCGAGATTTTGTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015150222.1|5181440_5183396_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|223562
NC_019693.1|WP_015150213.1|5157548_5158097_+|chemotaxis-signal-transduction-protein	unknown	unknown	gnl|CDD|238374
NC_019693.1|WP_015150220.1|5178629_5179061_-|hypothetical-protein	unknown	unknown	gnl|CDD|274350
NC_019693.1|WP_015150231.1|5193358_5194858_-|glycosyl-hydrolase-family-57	unknown	unknown	gnl|CDD|212110
NC_019693.1|WP_015150225.1|5185426_5185849_+|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|223725
NC_019693.1|WP_015150223.1|5183580_5184204_+|transcription-activator	unknown	unknown	gnl|CDD|381692
NC_019693.1|WP_015150216.1|5168223_5169078_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150227.1|5187155_5189630_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|223715
NC_019693.1|WP_015150214.1|5159300_5162528_+|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|214599
NC_019693.1|WP_015150229.1|5192648_5192927_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150221.1|5179620_5180673_-|glycoside-hydrolase-family-104-protein	unknown	unknown	gnl|CDD|381598
NC_019693.1|WP_015150217.1|5169772_5171671_-|response-regulator	unknown	unknown	gnl|CDD|381147
NC_019693.1|WP_015150228.1|5190441_5192511_+|S9-family-peptidase	unknown	unknown	gnl|CDD|224422
NC_019693.1|WP_015150230.1|5192931_5193171_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150215.1|5163000_5167764_+|response-regulator	unknown	unknown	gnl|CDD|223716
NC_019693.1|WP_015150224.1|5184270_5184987_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_052315773.1|5158135_5158582_-|transposase	Cas14c_CAS-V-F	-	gnl|CDD|284650
NC_019693.1|WP_044197565.1|5185906_5187031_-|RNA-methyltransferase	unknown	unknown	gnl|CDD|236981
NC_019693.1|WP_015150218.1|5171667_5176869_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|274362
NC_019693.1|WP_015150219.1|5178095_5178455_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_052315773.1|5158135_5158582_-|transposase	Cas14c_CAS-V-F	-	5.1e-12	39.8	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015150222.1|5181440_5183396_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl|CDD|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NC_019693.1|WP_015150213.1|5157548_5158097_+|chemotaxis-signal-transduction-protein	gnl|CDD|238374	cd00732, CheW, CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together with CheA and the methyl-accepting chemotaxis proteins (MCPs), which are involved in response modulation.	1.09506e-25
NC_019693.1|WP_015150220.1|5178629_5179061_-|hypothetical-protein	gnl|CDD|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	7.95062e-06
NC_019693.1|WP_015150217.1|5169772_5171671_-|response-regulator	gnl|CDD|381147	cd19920, REC_PA4781-like, phosphoacceptor receiver (REC) domain of cyclic di-GMP phosphodiesterase PA4781 and similar domains. Pseudomonas aeruginosa cyclic di-GMP phosphodiesterase PA4781 contains an N-terminal REC domain and a C-terminal catalytic HD-GYP domain, characteristics of RpfG family response regulators. PA4781 is involved in cyclic di-3',5'-GMP (c-di-GMP) hydrolysis/degradation in a two-step reaction via the linear intermediate pGpG to produce GMP. Its unphosphorylated REC domain prevents accessibility of c-di-GMP to the active site. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.74751e-54
NC_019693.1|WP_015150225.1|5185426_5185849_+|peptidylprolyl-isomerase	gnl|CDD|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	1.41593e-62
NC_019693.1|WP_044197565.1|5185906_5187031_-|RNA-methyltransferase	gnl|CDD|236981	PRK11783, rlmL, bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL.	7.28628e-155
NC_019693.1|WP_015150227.1|5187155_5189630_-|PAS-domain-S-box-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	4.78172e-46
NC_019693.1|WP_015150214.1|5159300_5162528_+|HAMP-domain-containing-protein	gnl|CDD|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	8.08603e-72
NC_019693.1|WP_015150215.1|5163000_5167764_+|response-regulator	gnl|CDD|223716	COG0643, CheA, Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms].	1.8463e-173
NC_019693.1|WP_015150223.1|5183580_5184204_+|transcription-activator	gnl|CDD|381692	cd19357, TenA_E_At3g16990-like, TenA_E proteins similar to Arabidopsis thaliana At3g16990. This family of TenA proteins belongs to the TenA_E class, and lacks the conserved active site Cys residue of the TenA_C class; most have a pair of structurally conserved Glu residues in the active site. TenA_C proteins (EC 3.5.99.2; aminopyrimidine aminohydrolase, also known as thiaminase II) catalyze the hydrolysis of the thiamin breakdown product 4-amino-5-amino-methyl-2-methylpyrimidine (amino-HMP) to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) in a thiamin salvage pathway; the role of TenA_E proteins is less clear. Members of this family include Arabidopsis thaliana At3g16990, Zea mays GRMZM2G080501, and Pyrococcus furiosus PF1337, among others. Arabidopsis thaliana TenA_E hydrolyzes amino-HMP to AMP, and the N-formyl derivative of amino-HMP to amino-HMP, but does not hydrolyze thiamin; nor does it have activity with other thiamine degradation products such as thiamine mono- or diphosphate, oxythiamine, oxothiamine, thiamine disulfide, desthiothiamine or thiochrome as substrates. Structural studies of P. furiosus PF1337 strongly support its enzymatic function in thiamine biosynthesis. It has also been suggested that TenA proteins act as transcriptional regulators based on changes in gene-expression patterns when TenA is overexpressed in Bacillus subtilis, however this effect may be indirect.	1.77218e-67
NC_019693.1|WP_015150228.1|5190441_5192511_+|S9-family-peptidase	gnl|CDD|224422	COG1505, COG1505, Serine proteases of the peptidase family S9A [Amino acid transport and metabolism].	0
NC_019693.1|WP_015150221.1|5179620_5180673_-|glycoside-hydrolase-family-104-protein	gnl|CDD|381598	cd00736, lambda_lys-like, Bacteriophage lambda lysozyme and similar proteins. Lysozyme from bacteriophage lambda hydrolyzes the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc), as do other lysozymes. However, unlike other lysozymes, bacteriophage lambda does not produce a reducing end upon cleavage of the peptidoglycan, but rather uses the 6-OH of the same MurNAc residue to produce a 1,6-anhydromuramic acid terminal residue and is therefore a lytic transglycosylase. An identical 1,6-anhydro bond is formed in bacterial peptidoglycans by the action of the lytic transglycosylases of E. coli, though they differ structurally.	1.04789e-61
NC_019693.1|WP_052315773.1|5158135_5158582_-|transposase	gnl|CDD|284650	pfam07282, OrfB_Zn_ribbon, Putative transposase DNA-binding domain. This putative domain is found at the C-terminus of a large number of transposase proteins. This domain contains four conserved cysteines suggestive of a zinc binding domain. Given the need for transposases to bind DNA as well as the large number of DNA-binding zinc fingers we hypothesize this domain is DNA-binding.	1.49695e-10
NC_019693.1|WP_015150218.1|5171667_5176869_-|PAS-domain-S-box-protein	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	1.36695e-75
NC_019693.1|WP_015150231.1|5193358_5194858_-|glycosyl-hydrolase-family-57	gnl|CDD|212110	cd10798, GH57N_like_1, Uncharacterized subfamily of glycoside hydrolase family 57 (GH57). This subfamily of uncharacterized bacterial proteins, shows high sequence homology to glycoside hydrolase family 57 (GH57). Glycoside hydrolase family 57(GH57) is a chiefly prokaryotic family with the majority of thermostable enzymes coming from extremophiles (many of these are archaeal hyperthermophiles), which exhibit the enzyme specificities of alpha-amylase (EC 3.2.1.1), 4-alpha-glucanotransferase (EC 2.4.1.25), amylopullulanase (EC 3.2.1.1/41), and alpha-galactosidase (EC 3.2.1.22).	1.29695e-137

Protein sequences

>NC_019693.1|WP_015150221.1|5179620_5180673_-|glycoside-hydrolase-family-104-protein
MNQDSLKTPIPPDCEVIQLWLQQQPPHQRRDRRLWVREFLAFVRKPLAAVTLVDVRAFAQTLAARRIPPEQAQARLFVLKSLFAYGYHQGQLPINIPLQHWPKVRVKRPSPSGSAILTGVLSNLKSTFRQRFGRGPRKPATLQKQAAFWGGVCLAGVALAIPAHFNSQAETTEEVTIPQPALQVRRQTVASLKAAHVQAFLDTIAWAEGTAGPNAYRMQFTGTQFSGFQDHPREIKCGSSYGSRLCSDAAGKYQFLSTTWDRMAKKIGASDFSPANQDRAAIALLDEYGVLEDIEAGAFAYAAIQLIPVWPSFQDVGNGDRTRAIARLERVYEQKLRKHSFEPAAFRIQN
>NC_019693.1|WP_015150220.1|5178629_5179061_-|hypothetical-protein
MKGIYNIVTVLAISLGMGIAPPAIAENLSQPSVRESQGVIEVDSYDFVVLAEEALEVADYQNAIFHANRAIDIAPALGNAYLIRGQARAYQGEIQAAIADLEQAAQVYRQNNNQIGYLLALEYLRDLNAPSSPQALTLPDLSD
>NC_019693.1|WP_015150219.1|5178095_5178455_-|hypothetical-protein
MTLKATPAQLHYLQHLENPFNQAAQRIHTLQRRAISAIVITLLLLILTYTLDVLSAWASIATSTALSTLCLLNIISTTLTLLTGIAGIGAAMTFVSYRAKVLRCGSPKEKTQGPLALQE
>NC_019693.1|WP_015150218.1|5171667_5176869_-|PAS-domain-S-box-protein
MNLGPIHIVEKNSLMIAPDTGVSEAVTLMSQQRVSCALVVDNHQLVGILTERDVVRMTAEAIDLNTVKVAAIMTPDPVRIVVSSALEIFSVLSTLRQHKIRHLPAIDESGNILGVITQNSIRKVLQPTDLLKFQKVYQVMSDRVIHLPQTAGLWEITQQMTQSQVSCIVIVEDTDEQETIPMGIITERDIVNFRALNLNLAEWVASQVMSTPLFPIKTGDSLWDAHQLMENNGIRRLVVVNEAGNLTGILTQTSLLEALDPIEMYRTLEVLQEQVNRRVIEVNQVNERLQEEITLREQELQERSRLEAELKAQNAQLQAEIGDRIRVEAALAQREREFRALVEHAPDLIWRFNREFRYLYANPSSESLFGIPSGEILGKTIEELGFPDAVLSQWIEVLQQASETGTEQTLECAVPRRDGVKWWFARIVPELGNNGEVESILAIVRDISDRKQTEQERLQLLDLEQTARAEAEAATNRVRNILESITDAFFSLDSNWRFTYINSQAQVLFQRSQEELLGQSLWVEFPEARHGRFYEEYHRVVTENISREFLEFYPPLNRWFEIHAYPAKDGISVYFEDVTEQIRAEASLKESEQFLRSIYEGVETAIFIVDVLTDGTFRYFDSNPTHERIWQISAEEMSGITPEQLLHQAVADEVMQRYQHCIETRERITYEEKLTLEGQESWWLTHLSPIFDSSDRIYRLIGTSFNITDRKQAEIALEQQLKREQLLNAIQERIRSSLNLEEVLTTAAHEVRQFLSNDRLLIYRVDPDGTGIVVTHSSDPLAPEINGNTFPQETFSQEERDRYAQGEIVAIADTELVKHLPCLAALIKTLKIKAKLVIPILKEQNLWGLLIAHHCQGPREWHPSEIESLRSIAGQLAIAVQQSTLFEQAKAELIERQKAEEALQTSQRFVQNIADTSPNLLYIYDILEQRNIYVNREIVEMLGYSDEEISNLGNNLLPALIHPDDLGKIPEHFQNLSQAQEGDVFELEYRMRTIQGEWRNVLVRETIFTRTKNGAVKQLLGTATDITKIKQSEAALRESAEREKAVASAVQRIRQSLDLGTIFAATTEELQGCLTCDIVAIYRFNPDYSGEFVSEAITSQRVSVLQRNRQSLHLSAQPASGENCQMQALINSCLEWQDTHLIQTKGDAFNRDENCLVVEDIYQRNFSPCYLARLEEFQVRAYIIVPIFCGSKLWGLLAAYESDRPRQWQPSDHKIVIQIGNQLGVALQQAELLEQTQKQSDALQKAAIAADAANQAKSEFLANMSHELRTPLNAILGFTQLMNRNSSLSPQHQEYLKIINQAGEHLLSLINDILEMSKIEAGRTVLNPTSFHLISLLRNLEAMLKVQAQSKGLELNFELDSNLPGMIMSDESKLRQVLINILGNAIKFTNSGRVTLRAQLEPDVNNNSLNKSPIFSETPSILGIEIADTGSGIAPEEMNHLFEPFSQTETGRKSQQGTGLGLPISRKFIQLMGGDIHVSSTVGVGTVFSFEIQIVPINETLEPPTPTPRQVIGLDCDQECYRILVVDDAVNNRRFLVTLLSEIGFEVLEAENGQEAIALWSSWDPHLICMDMQMPVLDGYQATQQIKASRKGQDTVIIALTASAFEEERKGILSCGCDDFLHKPFREEVLFEKISTHLGIRYRYAPEIPHSPQVLSSRPNLLNRDEIKSYLFQMPPNFVTELYQFASQGYDEGIFELLKFIPEESSPLAQTLRELTKNFDFELIIELTEQEEA
>NC_019693.1|WP_015150217.1|5169772_5171671_-|response-regulator
MNYALGELTTSRQSQNNRPNILVVDDTPDNVRLLSSVLTDNGYRVCKALKGDMALTVCKNAVPDLILLDVMMPGMDGYEVCKCLKQQETTRQIPVIFLSALNEVDDKVKAFEAGGVDYISKPFQEAEVLSRVQTHLKLRQLQINLQEKNLCLEQEITERQNAQRSLEVSEAKNMALVNAIPDVMFRIGEDGFFLDYRSPSLGCLDDIPESPGNQRGNPLQKSRDFTQNIFPISESLAADSSFVGKHIQEVLSDDLAIWIMHYVQQTLVTSKIQIGEYVQRDKNQERWVSYEVRFVKSGPSEVLAIARDISSRKQADAARLQAEAIMRHQKQKIEQALTELQDAQVQLVQNEKMVGLGQLVAGIAHEINNPVNFIYGNISHVQSAIADLVNLLETYQKEHPPNQTVREILEELDFDFLSKDLRKMTSSIAVGAERINQIVLSLRKFSLMDESGVKKVDIHENLDTALILLKHRFKITETHEIELIKDYGEIPQILCYPGELNQVFFNLLNNAIDVLSDILPDRLKVQEANPTAPKFVPSIWISTALTNSQTLLIRIKDNGPGINESGRSRLFDPFFTTKPVGKGRGLGLSISYQIVVQKHGGQLTCNSTPGEGAEFVIELPLVQSTADPVGLS
>NC_019693.1|WP_015150216.1|5168223_5169078_-|hypothetical-protein
MFNSTALLIEAFVDRLQEGYHRTYGGYKPDYAEILAWAGGMALENIANSDALYHNVEHTILVTLVGQEILRGKHIREGGVSCEDWLHFIISLLCHDIGYVKGVCRQDEDSKRLYATGRDGLKVPIPFGSTDASLTPYHVDRGKLFISERFGGHSLIDAEVIKRNIELTRFPVPADEDHKDTFNYAGMVRAADLIGQLSDPRYLQKIAALFYEFDETGANKKLNYSHPGDLRRNYPKFYWHGVFPFITQALAYLNLTQQGKQIVANLYANVFKIEHEDQQLSEVA
>NC_019693.1|WP_015150215.1|5163000_5167764_+|response-regulator
MQPEQRQRIMGYFIEETTEHLNTIEQGLQNLASAVQDPSALAELFRAAHSVKGGAGMLELTAIQQIAHKLEDEFKVLQLVPVEVDPQLESLFVRVFRGLQETVALIRVSGPLDEEKAAAICAEVQPAINQLHVHLAQLAEETESPSAFVTRKEPRPDIGGQHTRIQSPKNPGVEEYSAKQLIFKSDVSRLLQEMIHLFKQAENSRGRERMQEICRQWIRAGEQFDLKLWCHLIDQAATAIANPENTFRVLAPILIKEIQKAREQVLCGQAEAITVSPKLEGLLQPQPQPQKSLTPQILGESTHTDSKFNPMSNNSSNSDQNQRLFEGGDSHRKKNPDSQNNQTWGEEKRGGKPTYNSGPEVGAAELNTLADLFEGESSYFDENWEGEEVVEEANPGEGNRETLPPDPGEVLANANDFDDLLFEPPADERTQMGTSENNDEENLANLFGLEGFVEMDDSSISEKPQSPSGAVSRKSSNQKLDDLGELFEEVATEELKEPDDWEQMWDDEPLDAVSEIVPPEPEAEFSLEIDEDSEFKDLLDISGLESSRDPGKDPFVSEVATEIPIDEENFDDLFGETTEDQDFAPNLTASEDSVDWFDSDPSETLETEEDLLDLLELETVPSSSSPTPSEPVGKRKPAPTSPPSDEFWLDFEEPDSEPESDVLDALDGLFDDEPSPAIADLDLMEDSSLDSQLFDEELGAGDDNNDLFPESSGNLDGDEWDWDLDPNDSDDKEDTSDFYQNLESLFEEPTERSPTLDLNQIAQPSPGPSKKTQSNSGFSSSTESNLDFEALFGENEPLSPKSDLSKGMPVGISEPIRERLDLPPEPKLTQGADIFTELDYLLAMGPLKATFDELEILLNPLSSPKAGTTSTSTTPATVSATANSEKSLLRSRGSDVDPEKTDVDFDDMEKLLRASADIGSRDTGGRVAPRRGGFEQTMRVPVRQLDNLSNLVGELVVNRNSIEQNQERMRQFLDNLLHQVSQLTDVGQRMQDLYERSLLEISLLASRQNYHFMGGSRNTQKDQSHTGSDWSALEMDRFTPFHSLSQDILELIVRVRESASDIEFLVDETEQVTRQLRQVTTQLQEGLTRSRMVPFAQTADRLPRGVRDNAIKFGKQVELQVEGRETLIDKMILEQLSDPMTHLVNNALAHGVETPEERRKKGKPPVGRIVVRAFHQGNQTVISVSDDGAGIDSEKVKAKALQRGLISPEVAKIMTRLDVYDLLFMPGFSTRDKADDLAGRGVGMDVVRTSLSSIRGVVTIDSTLGKGTTFTIRLPLTLSISKALCCISDRARIAFPMDGVEDMIDVPRDRIKTQEDGQTFIPWRDTMLPFRHLRELLVYNRHLGRGVVYGANPEEDIISVVVLRSAGNFLALQVDQVLGEQEIVIKQLEGPVPKPVGVAGATVMGDGRIVAIADVLELLDLAAGRLRREGTGTLWEDALGNRIQPEPEQEAVIDPTVLIVDDSITVRELLSLTFNKAGYRVEQARDGQEAWEKMRSGLPCDLVFCDIEMPRMDGLELLSRMQKDPILTSLPIAMLTSRGADKHRQMAIQMGASGYFTKPYLEESLLEAAGRMLKGEKLVSLKMEAGV
>NC_019693.1|WP_015150214.1|5159300_5162528_+|HAMP-domain-containing-protein
MVSSTDYQQDYEQALTAYTEKNYEEAALIVNQLVANFPEDPSARLLAGHIYCYGLQMYDVALGQYEGVLSLTDDPAFIEGASQGIDYANQYATEGMQSSEYGYEADNEFQSAMPEDFESDFDSIQSEQDTALFELEAPAPSYEEEFWEEDNSALGLQDRAYNEALAINQIGSDDADLSMELDPVDPNLELESMEFDELAEFESGDLGGGSGTPEGGLLNPFTSEEAFEGIADEDPFAIDDEEILSEVQNNQWSDPLASELPDFLPRDDEMPDLVGEETGIRVSKQSPFDQGQDDLDLMDLATPFQEFEDAFAPEDEAEFDSNLDPLEDEEDTSYYSNNGSAIDSDFDLFDADDDFGNEFSEEDEDESPHQNGKGAGTSGIPYDIDEDFDFNAPSEEEETLLMGRQQLEQTQALNSISKASGPPYSQPKGLTQPNLEEDDDDDDYDSKTFVSEPTNGFNQADSYELEDFDDAFSGGNSFDSKPNGEDFPNSISNSSPLLQEEGVDFLGEFDDFEDFGNIPDNIPDFDLSEDTTGASTGGFGMGRMGPKASFQDIDDSYDIAEDTDGSIIRDDEIFRFAGSAEQVPVFTPPENTPVETVASAEPGIFGFLENASLVKKFLWIALISGGVSAIAAASVSFAFSSQRNWPQQLKDPMMALAAGGASILTCFGVGSASAKLIRRSIDDLHNQFDTMSQGNLSARATVYNEDEFGQLSAKFNQMGRIIYTTTSEAQRKAEEQEQSKEDLQRQVIRLLDDVEGAARGDLTVQAEVTADVLGAVADSFNLTIQNLREIVLQVKLAARQVTKGATDSESFARSLSSDALRQAEELAATLNSVQVMTDLIQRVADNAREAEEVAKSASATAKKGGEAVEQTVAGILEVRETVAETTRKVKRLAESTQEISKIVALIATIAGRTNLLALNASIEAARAGEAGRGFAIVADEVRQLADRSAKALKEIEQIVMQIQSETGGVMVAMEEGTQQVIEGTKRAEQAKRALENIIQVTNRIDVLVRSITADTVEQSQTSRSVAQVMQAVELTAQETSQEAQRVSGSLQNLVGVARDLLTSVERFRVETGERR
>NC_019693.1|WP_052315773.1|5158135_5158582_-|transposase
MRVAPLIKNHQGSAFLQGLEDLGKVFGVTTIAVPLQHLSQNSSNCGEFLKKSLSTRTHKCLICGFVLDTEGNADLKILQGIGCTGGPMVKVQWIWRHRPSASVGTSRKVSPGAESGKLSAEAGNSSGFRAQRRLTFGLGISLSYLQID
>NC_019693.1|WP_015150213.1|5157548_5158097_+|chemotaxis-signal-transduction-protein
MVGNPDFLTGIGLEQAPEFQELESPEGELHLRFFVPSGNEFALSATGIREVISQAPDRITLIPNVSSLLLGTLNVRGRVIWVADLGQFLGEPATLNTDRPEIPVIAVEDQDTILGLAVDQIVGMAWLDVEQVRLPTNVPDSMAPFLRGEWIIPPKEESKEEEEKILRLLDQVAIVRSARWAA
>NC_019693.1|WP_015150222.1|5181440_5183396_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MSIFTLQSVKKDFGIKEILRDASFSLNPTDKVGLIGTNGSGKSTLLKMIARLEPVDGGQILVNSGVRIVYLPQQPDLDENRTVLEQVFADCGDRMNLVREYEDLSHKIARNPEDGPLMARLSEVMHQMESSGAWELETQAKIILTQLGIEDFDAQIGTLSGGYRKRIALAAALLSDPDVLLMDEPTNHLDAISVEWLQSYLNSFRGAILLITHDRYFLDRVTNRIIELDRGELYTYDGNYSYYLEKKALAEEAAASQERKHYGVLRRELEWLSRGPKARSTKQKARIGRAMDLQDKEFKQSLGKVEISTASRRIGKKAIELENVSKAYGDRTLIQDFSYKFSPDDRIGIIGKNGIGKSTLLDIITGRLAPDSGTVEIGSTIHIGYFDQHCDDLLDAADQNQRAIEYVKEEAELVQTADGLQITASQMLERFLFPPNQQYLPIHKLSGGEKRRLFLLRVLMSAPNILILDEPTNDLDVQTLSVLEDYLEDFNGCAIVVSHDRYFLDRTVNTIFALEEGGNLRQYPGNYTVYLDYQKAEAVEAARQATANQNEKKPDSQTATVDKSERVSWDKNRQRKLSSKEKREYQQLETKIAEMEAEKAATEKALYHAEPGAVTEVQKLHQKVQDLAHEIEVATERWMELAEIESASSSN
>NC_019693.1|WP_015150223.1|5183580_5184204_+|transcription-activator
MTITCQEILKNHQPLWQEATVHPFLEGCKQGTITPEQFNTWLVQDYQFVVEFTRMLARILSVAPLHHFDVLLGGLIALKDELNWFQVKAAERNLSLDVAKQRTCEEYSQFLANLARTPYAVQATGLWAVELAYNQGWQLPGPMPEPYTEFADRWGNPGFTDYVKLLEQQADEMLSNASPEVQKEAEQTVITVAQFEKAFWQMAFNAT
>NC_019693.1|WP_015150224.1|5184270_5184987_-|hypothetical-protein
MDSEQTQEILSLREKKLTPKQIARKMGLKVSDVTGFLKEQAEQAAIAREDSGELPPIVECLINANCVPRLFPPEDELVTQSEDDLENISDPGMAIVTVTRSPGFNRFIVCTYLVDYWCLGVKDASGPRKYNRSEYERITALYYDSFIGGSEKISLTQAQALVWGAVEYAEKLGLKPHHDFGKAKELLGEWDGELKIEFGQDGKPFYTSGPYDNSASIINSLNKSVGEGNYEYMIGMES
>NC_019693.1|WP_015150225.1|5185426_5185849_+|peptidylprolyl-isomerase
MPRAIMETDKGTIHLDLFDKDAPNTVDNFTKLSESGFYDGLTFHRVIPNFMIQGGCPNGTGTGGPGYKINCEINPNKHLAGTLSMAHAGRNTGGSQFFICHSPQPHLDGQHTVFGKTEDMDVVNSIRAGDKILSVKIEKD
>NC_019693.1|WP_044197565.1|5185906_5187031_-|RNA-methyltransferase
MTEYFATVARGLEPIAAQELERLGAQDVRPDFTGVHFSGDRALLYRVNLWGRTLFRVLVPIREFSCPNAEMLYREVQSIDWEEYLDPGHTLAVNCTGSNHKLNHTHFTALQVKNAIVDQQRDRTGERSTVDPKDPDLLLNLHIHGDRAILSLDSSGNSLHRRGYRPAMGTAPLKETLAAAILELAEYSPEQTFLDPLCGSGTLPLEAGLKALNIAPGLFRERFGFMSWRDFDLELWQDIRQEALDGQKAELTAPIFGSDRDRAVIQQAHLNAENCGLDAHVHFSIQEFYQIEPPAESGIFICNPPYGERLGEVHELGDFYKSMGDILKQRFTGWTAYILSGNKELTKKIGLKSSKRIPVYNGSLPCTLLKYELY
>NC_019693.1|WP_015150227.1|5187155_5189630_-|PAS-domain-S-box-protein
MAKILIVDDDVTVQLVLQDLLESDGHRITVASDGTEGLRLARELEPDLIVCDWMMPGLDGLEVCQKIKADSELAPMFFILLTAREEVGDRIKGLNTGADDFLSKPIETEEFLARVRAALRLHGLTQELSQANQQLEALVEVQRRLLAFKGDTTPDNSPSYPYTEILKPLGQAAHASRVYLCQNPPLSMGNSTPTGPSPLLVAQWNCEELKIQPGSDSNPQPAQCLSLKAPILIERWVSLLARGEVIADVVSNFPDSERELLEQSGIQSLLILPLIVHGEFFGFIRFDNCTEPRVWSESEVSILQAAAAAVSLHKERALAEVALRSSEARYRAIVEDQTELICRFAPDGTLTFVNDAYCRYFGVSRKELMDGSVVSLIPDIDRNPVAMPVVTRERRIMLTNGEVRWQQWTDRAIFDAQGVLSEFQAVGRDITEQKLAEAAVQASEERFRQLAENIEEVFWISDPNYSQILYVSPAYEEIWGLERQELYEKPTARLDAIHPDDRQAVLTGLMPLDRLDREYRIIRPDGSIRWIRDRGFPIRDEEGKIYRIAGISEDITEIKRAEEQLRHALAKEREIMEFRTRFVSMVSHEFRTPMTTILSSADLLEYYLEEWPNDKLDKKFQALHRIQSATVNMTQLLEDVLFIGRAEMSQLPFNPQSLDLVPFCKGIVEEFQFSSTKNYTINFVENYSEEFLSRKSRKPCFDEKLLRYILNNLLSNAIKYSPEGGEVYFELTCTDTDVTFMIKDSGIGIPSEEIPRLFQTFHRCGNVGNIPGTGLGLAMVKRSTDLHGGEISVKSEVGFGTAFTVRLPLYSRQREEDSSSQQVG
>NC_019693.1|WP_015150228.1|5190441_5192511_+|S9-family-peptidase
MSYFDGTLSYPKTRKGDLVDDYHGIQISDPYRWLEDPDAEETRAWVEAQNTVTFAYLNEIPQRDRLKHRLTELWDYEKYGIPFKKGSRYFYFKNDGLQNQSVLYVLNHLDDQPRVLLDPNKLSEDGTIALAGIAISENAQFMAYGLSSSGSDWQEWKVRDIETGEDLSDHLQWIKFSGASWTHDHQGFFYSRYDEPNTKGQYEDVNYYQKLFYHRLGTPQSDDILIYDRPDQKEWGFSGGVSEDGTVLIISVWRGSDPKNLVFYKDLTHPDASVIELITEFEAQYGFIDKEGDLFWFQTDLDAPRGRAISLNIRTGDRQELIPEAPETLESIGLLNNQFVADYLKDARSQIKLFNLDGSFIREVELPGIGSAGGFNGKRHDTETFYSFTSFTTPPTIYHYDMVTGESTVYRHPQVDFNPDDYTTEQIFYTSKDGTQVPMFIIHKQGIQRDGNNPTYLYGYGGFNISLTPSFSVSQVVWMELGGIIAIPNLRGGGEYGEDWHQGGTKLNKQNVFDDFIAAAEWLIEHGYTKSQKLAIAGGSNGGLLVGACMTQRPDLFAAALPAVGVMDMLRFHKFTIGWAWCSDYGSPDNPDEFKALYAYSPLHNLKPGTAYPATLITTADHDDRVVPAHSFKFAAALQAAHTSKAPVLIRIETKAGHGAGKPTAKIIEEVADKWAFLVRTLEMDIPVK
>NC_019693.1|WP_015150229.1|5192648_5192927_-|hypothetical-protein
MAFEMKICEIFKLQSGQTVFAGPLEGTSISIQNCQAELEVDGVIIQKLMIEGEFIMNVKHPVGHRAIFTTESVKINRSIIKQQTCYLRSVNF
>NC_019693.1|WP_015150230.1|5192931_5193171_-|hypothetical-protein
MSSGDHNHIIIRPDARKIELLEEFLHATQIKFGILDKLGHHAAEINVKDFMIKHQKMINLSQKDIDSLVIMRDSYINSQ
>NC_019693.1|WP_015150231.1|5193358_5194858_-|glycosyl-hydrolase-family-57
MVSIAPTSTDIPKLEEFAQGLPNICGWENAVRSVVQRNEPVFLPITNIRLEDISAAFAIALHMHQPTIPAGPNGEYIGHLQYMFEHTGEGDNHNAGPFSWCYSRMGEFIPELVANGCNPRVMLDYSGNLLWGLRQMGRHDVIDSLKRITCDPQYYLHVEWLGTMWSHAVVPSTPLPDLKLHIQAWQHYFASIFGWEALARVKGFSPPEMHLPNHPDTLFEFIKALKESGYRWIMVQEHSVETLEGHSLGYKHLPHRLIARNSQGETTSITALIKTQGSDTKLVAQMQPYYEAKTLSKQQMGSVTVPPIVTQIGDGENGGVMMNEFPDGFKRTTYEIAQNNGGKSGTVALNGTEYLELIEAAGCSPDDYPTCQAVQQHKIWQRLDPENVTPEKMAEAIAQLKQEDHQFHVDGSSWTNNLNWVQGYENVVGPMNSLSALFHQKIDPLLGDENLTQQPRYRQALLNNLLTQTSCFRYWGQGMWTDFARSIYERAIEQLNNDF

Crispr_ID: NC_019693_54

• CRISPR_ID: NC_019693_54
• CRISPR_location: 5228788-5229068
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NC_019693_54

Consensus_repeat	Method
AGGGCCTGCGCATTGCGCCCCTACAAGAAATAACGAT	CRT

spacers of NC_019693_54

>54.1|5228825|28|NC_019693|CRT
TTGGGGTCATTAAATTGAACACCTGTCC
>54.2|5228890|20|NC_019693|CRT
ATTAAATTGAACACCTGTCC
>54.3|5228947|28|NC_019693|CRT
TTGGGGTCATTAAATTTACCACCACAAG
>54.4|5229012|20|NC_019693|CRT
ATTAAATTGAACACCTGTCC

CRISPR arrays and Neighbor proteins around NC_019693_54

CRISPR arrays

The CRISPR arrays of NC_019693_54

>merge|NC_019693|54|5228788-5229068|CRT
AGGGCGCAAGCATTGCGCCCCTACAAGAAATAACGATTTGGGGTCATTAAATTGAACACCTGTCCAGGGCCTGCGCATTGCGCCCCTACAAGAAATAACGATATTAAATTGAACACCTGTCCAGGGCCTGCGCATTGCGCCCCTACAAGAAATAACGATTTGGGGTCATTAAATTTACCACCACAAGAGGGCCTGCGCATTGCGCCCCTACAAGAAATAACAATATTAAATTGAACACCTGTCCAGGGCCTGCGCATTGCGCCCCTACAAGAAATAACGAT

>NC_019693|54|3|5228788-5229068|CRT
AGGGCGCAAGCATTGCGCCCCTACAAGAAATAACGAT	TTGGGGTCATTAAATTGAACACCTGTCC
AGGGCCTGCGCATTGCGCCCCTACAAGAAATAACGAT	ATTAAATTGAACACCTGTCC
AGGGCCTGCGCATTGCGCCCCTACAAGAAATAACGAT	TTGGGGTCATTAAATTTACCACCACAAG
AGGGCCTGCGCATTGCGCCCCTACAAGAAATAACAAT	ATTAAATTGAACACCTGTCC
AGGGCCTGCGCATTGCGCCCCTACAAGAAATAACGAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015150262.1|5238708_5239677_+|stage-II-sporulation-protein-M	unknown	unknown	gnl|CDD|224219
NC_019693.1|WP_015150248.1|5218533_5219292_+|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|275293
NC_019693.1|WP_015150259.1|5232610_5234098_+|TldD/PmbA-family-protein	unknown	unknown	gnl|CDD|223389
NC_019693.1|WP_015150246.1|5215356_5216406_+|YdcF-family-protein	unknown	unknown	gnl|CDD|376902
NC_019693.1|WP_015150247.1|5216618_5218364_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NC_019693.1|WP_015150251.1|5222623_5225197_+|PAS-domain-containing-protein	unknown	unknown	gnl|CDD|223715
NC_019693.1|WP_015150249.1|5219423_5219882_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150256.1|5227431_5228355_+|chemotaxis-protein	unknown	unknown	gnl|CDD|223716
NC_019693.1|WP_015150266.1|5243190_5244318_-|DUF4350-domain-containing-protein	unknown	unknown	gnl|CDD|379527
NC_019693.1|WP_015150253.1|5225974_5226370_+|DUF1830-domain-containing-protein	unknown	unknown	gnl|CDD|370162
NC_019693.1|WP_083896805.1|5229854_5230913_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|132489
NC_019693.1|WP_015150258.1|5231465_5232539_+|M20/M25/M40-family-metallo-hydrolase	unknown	unknown	gnl|CDD|349893
NC_019693.1|WP_015150250.1|5220304_5222395_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|378963
NC_019693.1|WP_015150255.1|5226729_5227266_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150252.1|5225248_5225686_-|MgtC/SapB-family-protein	unknown	unknown	gnl|CDD|224204
NC_019693.1|WP_015150260.1|5234519_5237387_+|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|238923
NC_019693.1|WP_015150265.1|5242221_5243172_-|MoxR-family-ATPase	unknown	unknown	gnl|CDD|223786
NC_019693.1|WP_015150263.1|5239832_5240732_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150261.1|5237434_5238226_-|RDD-family-protein	unknown	unknown	gnl|CDD|224628
NC_019693.1|WP_015150264.1|5240799_5242110_-|DUF58-domain-containing-protein	unknown	unknown	gnl|CDD|224635

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015150262.1|5238708_5239677_+|stage-II-sporulation-protein-M	gnl|CDD|224219	COG1300, SpoIIM, Uncharacterized membrane protein [Function unknown].	1.61786e-52
NC_019693.1|WP_015150248.1|5218533_5219292_+|peptidylprolyl-isomerase	gnl|CDD|275293	TIGR04500, PpiC_rel_mature, putative peptide maturation system protein. Members of this protein family have a novel N-terminal sequence region. Close homologs to the C-terminal region of this protein score well to PpiC-type peptidyl-prolyl cis-trans isomerase models (see pfam00639), yet no sequence within the family scores well to such models, suggesting origin within a branch of the PpiC family but subsequent neofunctionalization with a rapid change of sequence. The genome context for members always includes an ATP-grasp enzyme associated with peptide modification and a short polypeptide likely to be the modification target.	3.48184e-12
NC_019693.1|WP_015150259.1|5232610_5234098_+|TldD/PmbA-family-protein	gnl|CDD|223389	COG0312, TldD, Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only].	4.57199e-92
NC_019693.1|WP_015150246.1|5215356_5216406_+|YdcF-family-protein	gnl|CDD|376902	pfam02698, DUF218, DUF218 domain. This large family of proteins contains several highly conserved charged amino acids, suggesting this may be an enzymatic domain (Bateman A pers. obs). The family includes SanA, which is involved in Vancomycin resistance. This protein may be involved in murein synthesis.	3.56673e-11
NC_019693.1|WP_015150247.1|5216618_5218364_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	7.63836e-155
NC_019693.1|WP_015150251.1|5222623_5225197_+|PAS-domain-containing-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.29908e-43
NC_019693.1|WP_015150261.1|5237434_5238226_-|RDD-family-protein	gnl|CDD|224628	COG1714, COG1714, Predicted membrane protein/domain [Function unknown].	1.2446e-17
NC_019693.1|WP_015150256.1|5227431_5228355_+|chemotaxis-protein	gnl|CDD|223716	COG0643, CheA, Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms].	7.30854e-29
NC_019693.1|WP_015150253.1|5225974_5226370_+|DUF1830-domain-containing-protein	gnl|CDD|370162	pfam08865, DUF1830, Domain of unknown function (DUF1830). This family of short proteins is functionally uncharacterized.	8.39529e-29
NC_019693.1|WP_083896805.1|5229854_5230913_+|GNAT-family-N-acetyltransferase	gnl|CDD|132489	TIGR03448, mycothiol_MshD, mycothiol synthase. Members of this family are MshD, the acetyltransferase that catalyzes the final step of mycothiol biosynthesis in various members of the Actinomyctes, Mycothiol replaces glutathione in these species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs].	1.63337e-11
NC_019693.1|WP_015150258.1|5231465_5232539_+|M20/M25/M40-family-metallo-hydrolase	gnl|CDD|349893	cd05640, M28_like, M28 Zn-peptidase; uncharacterized subfamily. Peptidase family M28 (also called aminopeptidase Y family), uncharacterized subfamily. The M28 family contains aminopeptidases as well as carboxypeptidases. They have co-catalytic zinc ions; each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water; one aspartate residue binds both metal ions.	2.64852e-66
NC_019693.1|WP_015150250.1|5220304_5222395_-|FAD-dependent-oxidoreductase	gnl|CDD|378963	pfam12831, FAD_oxidored, FAD dependent oxidoreductase. This family of proteins contains FAD dependent oxidoreductases and related proteins.	5.10394e-26
NC_019693.1|WP_015150252.1|5225248_5225686_-|MgtC/SapB-family-protein	gnl|CDD|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	3.94584e-36
NC_019693.1|WP_015150260.1|5234519_5237387_+|EAL-domain-containing-protein	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	2.42663e-111
NC_019693.1|WP_015150265.1|5242221_5243172_-|MoxR-family-ATPase	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	2.13892e-103
NC_019693.1|WP_015150266.1|5243190_5244318_-|DUF4350-domain-containing-protein	gnl|CDD|379527	pfam14258, DUF4350, Domain of unknown function (DUF4350). This domain family is found in bacteria, archaea and eukaryotes, and is approximately 70 amino acids in length.	0.00618496
NC_019693.1|WP_015150264.1|5240799_5242110_-|DUF58-domain-containing-protein	gnl|CDD|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	4.7445e-76

Protein sequences

>NC_019693.1|WP_015150256.1|5227431_5228355_+|chemotaxis-protein
MDPEKQQQIMGYFIEEAREHLETIEKGLLELQSTMNDQEQLNELFRAAHSVKGGAAMLGFGSIQKTAHSLEDCFKILKEEPVPVDQKLETLFLKGYDTLQKLLERLQGPFGLREEDGAEIVKESQPVFEELKKYLDTLVKGGGEGDADPTRRDLGLEIANEVINLLRQMLMLFKQKPDAENRKRIGTLCNQLAEMSPQMQNWQSLVKTAAGAIANPSNSYDLIAPVTIKELKYASDFIAVGKPDTMPPSSLLLELAGQSPKQAGITLNEQEFIIKAEPQAAAKKLIETFDKKQLTVLTKLLVKAVKS
>NC_019693.1|WP_015150255.1|5226729_5227266_+|hypothetical-protein
MRTYTMQESTQVASRATADITQWLQNSPRTLSIQNVENDPNYQAIDVDLVVKTDRGESKLEIKGDRYHKTGNFFFETHSNREKNTPGCFLYTQADWLCYYFVEIGLLYLLPMPQTRNWFLNHIERFPSKSTTTPIRGGGCYTTVGRLVPIAVVLQEVPEVKRFELCSVRDGRSEKKED
>NC_019693.1|WP_015150253.1|5225974_5226370_+|DUF1830-domain-containing-protein
MSLDRGDPRSSYGKKIKENSEKNEMAMPKSTNSLSCSSSDAILCYYLNSTSEIQVIKSECRDTWEFERVVFPGQRLFFEAISTAQLEIYKAKNSGLQLAARVKCDRLQVVQERRSSFTTVSQFLGQQLAAC
>NC_019693.1|WP_015150252.1|5225248_5225686_-|MgtC/SapB-family-protein
MSNLSTLAPVDTLHLLGRLGLSLFVGAVIGFNREREHKPAGLRTYMLVTFGTTLLALLPVQLGVALNSTDAFSRIIQGIVTGVSFLGGGTILRDRDRVRGLTSAAAIWVAAALGLLIGCGLWQLGLASVLICWVILRVVKQIEPL
>NC_019693.1|WP_015150251.1|5222623_5225197_+|PAS-domain-containing-protein
MHVTSSNLPMKPFETPGFDGSPSSEHPPQENEALLHSIVNNIPGAIYRCTYQGNWKIAFISKGIEQISGYPVSHFLHHPIARFKMLVHPEDQGIAQQTVEAALLSQQPYTLDYRIIKADGTIAWVREIGQGICDRQGHLCGLDGILSPLANIHSRPIDETSQELNPKIAPKRTILEQINEGFLNLDSQGQVIYINSQGENLLQTTHQTLCQPQETLALPPDLAQFFADLKTALSGTNPRPVEACYPYRETWLEVRAHPYDSGILVFLSDITSRKQVLNSLRQRENLYRTFVKNFPNGVILLFDPDLRHTLAEGRDLEAMHLTKTNVEGKTLQEAFPSDICHSLEPLYREVLTGETRLTELTFGSRIYLTQILPIKNEAGEVLGGMVMTQNMTECKLAESENARLIASLQRSEAKTRAMASLLSEAEKLAHVGCWEFEIATNRIICSDEVYRMLGLDLNAASPTYPEYLQKIHPEDRETAEQVMERAIQGGESYQVEQRILQSDGSIRYISANGEPIFNEAGEVVKVLGSLLDITDRHLSQQALIKSEAQLELRARELEKTLYELQRTQTQLIQTERMSGLGQMVAGIAHEVNNPVGFIYGNIAHATSYIDDLVNLVNLYQKHYPEPDPEIVDEIEEIDLEFLFEDLPRLLRSMKVGAERIREIVRSLRNFSRLDEADNKQVNIHEGIDSTLLILQHHLRDDSPEPNSNNNITVIKQYGDLPRVDCYPSELNQVFLNIITNAIDVLKPQKTPRQITIQTEAVIREQTSSEPPSPDWIIIRIIDNGPGMTAEIQQRMFDPFFTTKPVGMGTGLGLSISYQIIVEQHKGKLTCSSEPGKGTELIIELPVHQDYEEPALFE
>NC_019693.1|WP_015150250.1|5220304_5222395_-|FAD-dependent-oxidoreductase
MQRQTQGLPHPLVRSISLTRSCFSLLVSLITLALATSVADATPPRAPDQEVACEILVAGGGLAGAASAYESLLAGRTVCITDITDWIGGQISSQGTSALDERPTQRQQLFYPRGYLEFRESIRRKYGRLNPGQCWVSESCFMPYDGHKLLFDQLERAAKRGKGTLKWYPNTVIKELDISPTQEGEQIQSAVAIQIEPAPGQPPVNAESLSQILEDAYRYENSARFHKNIVRFVPMTRDRNARNTTTVAQPAQWYVIDATETGELIGLADIPYRLGVDPRSPLEPSSSSAQGNPYCTQGFTYTFAMQATEEPQQHIKPDFYDRYAPYYSYELERLANFNLVYTYRRIWSENYQKTLPSNPREYPINPGDISMQNWTWGNDYRPGTAQDNLIYTRQQLESTGQLQPGGWMGGLRTETLQAGEEHAIGFFYWLVQGTTDSQLGDGFKELHPNHRYLSGLDSPMGTANGLSKYPYMREGRRIIGRPGWGHPDGFMVWEIDISRADYSDEFYRTNLEPQEYRRLWESLSGLQTLETIGQRPNLDGRPSRSRSTIFPDSVGIAHYAIDFHPCMTLSPPEAPGNTELEGERRGAGTAYPFQIPLRALIPQRIDNLLIAGKSIATSHIAAAAYRVHSFEWSSGVAAGVTADFSLEKGILPYQLVDNLPLQEPQLEMLQTRLVDSGNPIAFPNTSIFNNTWEDWR
>NC_019693.1|WP_015150249.1|5219423_5219882_-|hypothetical-protein
MKRLIIVTASIVATVLLNSTLAISQPSETGGREPGFWQPETDVNVNLPINITLLNNAGTSLEYSLQDGGFRQIGAGTRVGLGNFLLNPTSETDLYRNLNVFINSPVGASEVPLHFDITSVGNDVTIAIRPAMTGERIDRGFYTDEKGRIYAF
>NC_019693.1|WP_015150248.1|5218533_5219292_+|peptidylprolyl-isomerase
METEKFITIDDETISLRQALGYLRTSGDLQQFIMKILRQHVIEQELQSQADLEIDGSLLEQAIINFRLQNQLVQSDRFDQWLQSQSLTYTTFRNQFAAGLKIEEIKTKVTAEQLEDYFQKNQQAFEQVVLSRIVVETFDKAIELKAQIEQTGASFEALAKEHSLAGEKAYNGMMGAILVSQLPPAIRDAISTAQPGDIVGPMELEGRYSLLRLEQRIPATLEGQLKRQLQEQLFEQWWQSKLQNKNVKLQVE
>NC_019693.1|WP_015150247.1|5216618_5218364_+|ABC-transporter-ATP-binding-protein
MARSKLQKLASYMRPHWKNALVGVVALFIVNAVGVYIPLLIRNAVDELEVTFSFDRILYFVGIILFLASVMWVIRVVSRMFLFGVGRQVEFDLKQGIFQHVLTLEPAYFALNPPGDLINRATSDVDNIRRLLGFAVLSLVNTIFAYGLTLPVMLAINVRLSLLAVAVYPFMLMIVQLFSARLRTQQLEVQEQLSGLSDLIQEDMSGISLIKIYAQEENERLAFRQLNQQYLRANLKLAQTRSFLFPVLGGLASLSLLVLLTFGAGAIANNEITVGDFIALLLYVERLVFPTALLGFTITAYQQGEVSIDRIESIFQAKPKIQDTPEAIALTEPAQGHLRANHLTYSYPEAQIPALNALSFEITPGETVAIVGPIGSGKSTLANAIPRLLDIGSGQLYLDGEDITNLKLETLRGNIAYVPQESFLFSTSIRNNIRYGKPLAEDPEIIETAKQAQIHPEILNFPQQYETMVGERGITLSGGQRQRMALARALLMDAPLLILDDALSSVDNQTATDILQNLSSGTQRKTVLFISHQMSAAASADRIFVMDRGAIVQVGTHTQLVEQPGLYQQLWNQQKLEALLH
>NC_019693.1|WP_015150246.1|5215356_5216406_+|YdcF-family-protein
MFLVITQLLLWVVVALLIWYVLLQLIPREYLTWLGGAILLSIIVLAFFFPTEQGVATLWYILSFPLRPLGLSLVLLCTATRRPKQRLHLVCAALTVLVLCSVPWLAQNYQYWLIRSNFPIASVCPAQGNPSLVPVVGRPEGIVLLSSGISQPSLPYQPELVEANMSDLIVTTVRQYQLQQQVGHSPRVIVAARPQPFPWQGVSAPWYSVNSTDILEADIIRSLLIAQGVSPTHIFVLNNVENVRESAAAVGELIPPLANRNPRVIVVASVLHLPRASLAFQRLDLDVIPRSPSLYPEICALDQARPSIYDIIPNATSLALTSRVVEEFYTLMYYFLRGWVEPCARCLSN
>NC_019693.1|WP_083896805.1|5229854_5230913_+|GNAT-family-N-acetyltransferase
MNLQFTFPLIDKCSGVCPVLFCQFFDFFMSIISRCPVAGETDLQQIADLVKTCEVDGLLDEDKSIADLKWIVTTSSVRSRRLWKDSNGHLRGFGQLWIPEPDKRLDGYLWFYVDPQDALQNSFTDGIIPLETEILDWAENRLREIGNKSGLSIHLHTKTRAEALIRISTLERHNFSLERTFLTLVKSDLETLPTPEFPSGFNVRSVEAPRDNQAWVDLYNESFIDHWDHHDLTLSSFQDWQQNPNYQPEFDLVAVAPDGTFAALCQSSLQTALPHSSKTGWIRWLGTRRGFRRMGLGRSILLAAMERLYAAGATSIKLGVDADSATGATRLYDAMGFRPVQSWLSYVKTVTT
>NC_019693.1|WP_015150258.1|5231465_5232539_+|M20/M25/M40-family-metallo-hydrolase
MRQKIWILLCLVSAIAILLVNLTRHQSPGSFDPQEAPLSQHPADPVPTLPEPSPLSMEFRRAPVVVSDRLMADLEALAFERSTPESREQSREYISSRLVAAGWTPQFQPFAGGINVIAKKPGRNPEAGSLLLGAHYDTVPGSAGASDNGTGVAVLLEVARLLQDRQTERSLELAFFDLEEIGLHGSFAFASDRNLVADLRGAIVVDMVGYACYQAGCQDYPSQLPIQPPSDRGDFIAVIGDTEHLPLLQVFQMETSADLPPVYTLPVPFKGLLIPDTLRSDHAPFWYQGIGAVLVTDTGNLRSPHYHQPSDTPQTIDRPFFIGSAQRIADAIVTLLESQGSLETNSIRTQALFRDVS
>NC_019693.1|WP_015150259.1|5232610_5234098_+|TldD/PmbA-family-protein
MLEAPTQITHQDLATEAIALIRQAGCEYGEIRLCRYRDRSLTARDRSLSNLSDRVSAGFGVRVLHQGSWGFAASPRRSSAEVRRIVALAVEIAKGSHLTQQTPVKLVPVETYRDSYRTPIAIDPFTIPIEEQAALLLEINERLLGYGDRGIKKAASFLRFTQEQKIFASTEGSLIDQTIYRSYPGYNCTAIANGDAQSRSYERPPLNCGYEHIDRTDLLGEVDRVATEAIAKVHAPKGPSGIKTTLILKPTNLFLTIHESVGHPTELDRVYGYEANFAGTSFATTDGLGSLQYAAPWVNFKADRTQPGGRGTMGYDDEGVISQEWHVVKDGILVDYLTDRETAARLGRGSSNGCAYADSWYNVPMVRIPNLGLEPGPDGGSHTATLAEAIADTEEGILIDGIGSYSIDQQRRNFQFGGDAFWQVKKGKVVGMLKDVTYQAMTTDFWKSVDAIGPKSEQIQCGTNLCGKGEPMQIAQMTHACVPVRVRDIFIGGPS
>NC_019693.1|WP_015150260.1|5234519_5237387_+|EAL-domain-containing-protein
MPQLKLSDSILNRQELASLDLLVCPIWIWDLDQKQVWWANAAALGLWQVQSIAELSEETRSNPFDENSSRIELEQLELKQLEQGATVVKQWTFQAGSEPVSIRCACSGIRIESGRMGVLVEGMTEVMKRHDWELWRSNEVLKQATVMISLYKTDGTMVMQNPVAQRCYGEENRGQNAWKGRFVRSSDAERALACLEAGNVFYHETQMQTLQGVRWHAVEIRNAKDPVTGDRAVLVNEKDITELKEAAVQLQQRDRLLEGVALATHALLTAPNLSEAISKALAELGNAAAVDRAYLVENYQSLTEEHLMRICWEWVSPGISSSQEKPEFQTLSYEENLPGWYETLCAGKAIGGRVKDLSNAEQSILEAQGIQSILVMPIAIEGQFWGFIGFNDCHEQRQWSETEESILKAAVGSIGGAIARHQAESKLATLNAQLEAIVEERTAKLKAANDRLRAEISEKAKIEEKLRHNAFHDALTELPNRTLFMQELRQEWERGKQNPNYLFAVLFLDLDRFKVINDSLGHGVGDRLLIEIAERLRKTLAVRPHSFRRNEHAIARLGGDEFAILLKDIRALRTARRVAERIHSCLTRPFAIEGQEVFTSVSIGIALSSRGYERPEDLLRDADIVMYRAKALGRSRHEVFDTAMHDRVVRLLKLENDLRRAISEGEKRLPTPRFYLSPTPDSEGHDSGEELEIQTPSLPFNAVKKPSAFTLHYQPIVCLKTGRIEGFEALLRWEHPELGLVPPGEFISIAEETGLIVPLGQWVLREACQQLRIWQERFPQALPLTVAVNLSGRQFSRVDLIAQVDRILAETGIDGSMLKLEITESAIVDNPELATEMLLQLKERKINLCMDDFGTGYSSLSYLHRFPLDTLKIDRSFVSRIGVEGENSEIVLTIVSLAHDLGMEVIAEGVETSAQLEKLQQLGCAMAQGYLFSPPVNSEQATQLLIQEGKLVTNW
>NC_019693.1|WP_015150261.1|5237434_5238226_-|RDD-family-protein
MFLLNRINIQTPESVNLEFTLAGIGNRAYALIFDYLILGLIQLALVLLWGFLSWFLADILLNTVATSSRAQQWLSAIWFLLLFAVYVGYFVWFEVFWQGQTPGKRRVQIRVIRDDGRPCGLQQSTLRALLRPVDDLLFIGAFLIALSSREKRVGDWVAGTLVIQEDRAIAEANFTLSESAKLLKNQLLERANLSALLPDDFAIIREYLQRRTQITIEARSQIGRQLATQVKRAIILEPLHKKVSAEEFLEAVYLAYQEQRSRP
>NC_019693.1|WP_015150262.1|5238708_5239677_+|stage-II-sporulation-protein-M
MNIQRWIARREPNWRRLDALLRQVEKKGLQSLQALEIEELASLYRSVSADLARARTHKLGMTLVQELQQLTSRSYSQIYQGSRRQEWGAVVEFVRWGFPAIVQETWGYIAVATATFVVGAFVAWWYAWQDPVFMAIVVPPHIIEIVRDQGELWMGSIVGIEPLASSSITINNLKVSFGAVGGGITAGIYTLFILVYNGIHIGAIATLIAQYNLSYPFWAFVWPHGSLELPAIFFAGAAGLLIGRGLLFPGQYRRVEALKFYGYQAAKLVFGIVPMLIIAGIIEGFFSPNPAIPDSLKYVTGISLLALLISYCTRRKPIEPSL
>NC_019693.1|WP_015150263.1|5239832_5240732_-|hypothetical-protein
MRYLSAENAATASINLYRKRFKTYFKISLVSHLWLLIPVYGWAKFYAGIALMSRLAFSEINGKTETINEAQTHINPRIWKFLVAAILASLGFAYRAFFWVLLWSICVGIISSLLVLVFSSLLALNYGLMALFGLLFLVVILCIYAWFFLKMIEIYSPFFIYEIPLAIEEEMTSSTTITRSRQLVEGLRRSVVKTIMIPFIATLPISILSILLWFLIVGLIQEGTSTTSEESTYSVIEQVVWVIYWGSFNILLTPFWQVLKSIAYYNLRCQKEAFDLPITLSSPALSDDAGDFMGLGSES
>NC_019693.1|WP_015150264.1|5240799_5242110_-|DUF58-domain-containing-protein
MIPSRLLYLLLGLGIIIAILTAMLFNPRVSILITLVFDCIILLLGLIDSQRGRNYRVKVTRHPLGKLSIGRDNPVVLTVESRNKSAVIRVGDRYPMAFEVSARQLQTTVAANTTQELTYTVKPSKRGEYEWGDIQVRQLGPWGLAWLNWTIPAGVKVPVYPDLVGLRSLTIRLALQSTGTMRQRMRRLGNGTEFAELREYGMGDDTRLIDWKATARRHRPLVRVLEPEREQTLLILLDRGRLMTAQVQGMQRFDWGLNATLSLVLAGLNRGDRVGVAVFDREIHTWIPPAQGQHQMPHLIERLTPLQPVLLEPDYMGAVTGVVSQQTRRALVVMITDIVDATASAELLGALQRLTPRYLPFCVTLRDPEVDKIAHTSTAEIDTTYSRAVALNLLSQRQLVFANLKQKGVLVLDAPANLISDQLVDRYLQLKARNLL
>NC_019693.1|WP_015150265.1|5242221_5243172_-|MoxR-family-ATPase
MSETRVILTRLGQALDKIVVGQSAVVQQLLVALLSGGHVILEGVPGTGKTLLVKVLARLIQADFRRIQLTPDILPSDILGTNIFDMNTSSFTLKQGPVFTEVLLADEINRTPPKTQAALLEAMEEQQITLDGESLPLPDLFWTIATQNPLEFEGTYPLPEAQLDRFLFKLVVDYPDPAAEKQMLLNSQAGFQAKRLELTQIKPLATVQHILKAREEVKGVQVADNLLDYVLNLVQKSRKFPDLALGASPRSAVAWLQSSKAQAWLKDRDYVTPDDVKVVALPLLRHRLILKPEALLDGVQIDSAIASLLQQVAVPR
>NC_019693.1|WP_015150266.1|5243190_5244318_-|DUF4350-domain-containing-protein
MNLSNRKLGVFLVLAIGAIILLTFVMAPASSGRINSGSTYRINPDGYGAWYAYMQSRQAPIQRWEKPGYELIENEELDTPVTFIHVDSRFTRQRRSESDSNLLSESEETWVSEGNILVILGVMTPVTEAPFSTLQDSPFGPVKIDTMRRVRNESQILLSDEFGAMVWQENIGQGKVIYANTPYLAANAYQEIPGNYEFLANLVSEGDWPIFIDEYSHGYKDTEVIEREQRQTLVNYFLQTPVFPALVQGIVLILVLIWANNRRLGQLNRVSTPGLENSKAYIQALAGVLQKAGRRDFIVKVVVKEEQVQLQKALGLGSVLLDAETLAQAWSEKTGRPSTELMQQLQVISNPRRLRELDLLRWLKKWAAIRRAISS

Crispr_ID: NC_019693_55

• CRISPR_ID: NC_019693_55
• CRISPR_location: 5519080-5519338
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_019693_55

Consensus_repeat	Method
GGAGTGGTTGAACCCGGAGGCGGTGGTG	CRISPRCasFinder

spacers of NC_019693_55

>55.1|5519108|47|NC_019693|CRISPRCasFinder
GGATAGGGATTCCGGGTCCCGGACCGGCAACAGGGGTGGGCCTTTCT
>55.2|5519183|53|NC_019693|CRISPRCasFinder
AGATCGGGGGTGGTGGGGGTGCAACCGGCCCCACTCCCGGTGTCGGTTGTTGG
>55.3|5519264|47|NC_019693|CRISPRCasFinder
GTATCGGTAGAGGTGGTCCAGCAGTTGCGTCGGGGGCCGGGATTCCT

CRISPR arrays and Neighbor proteins around NC_019693_55

CRISPR arrays

The CRISPR arrays of NC_019693_55

>merge|NC_019693|55|5519080-5519338|CRISPRCasFinder
GGAGTGGTTGAACCCGGAGGCGGTGGTGGGATAGGGATTCCGGGTCCCGGACCGGCAACAGGGGTGGGCCTTTCTGGAGTGGTTAAACCCGGAGGCGGTGGTGAGATCGGGGGTGGTGGGGGTGCAACCGGCCCCACTCCCGGTGTCGGTTGTTGGGGTTCGGTTGCGCCGGGACCCTGTGGTGGTATCGGTAGAGGTGGTCCAGCAGTTGCGTCGGGGGCCGGGATTCCTGGGGGGGTGGCAACAGGAGGCGGAGGTG

>NC_019693|55|53|5519080-5519338|CRISPRCasFinder
GGAGTGGTTGAACCCGGAGGCGGTGGTG	GGATAGGGATTCCGGGTCCCGGACCGGCAACAGGGGTGGGCCTTTCT
GGAGTGGTTAAACCCGGAGGCGGTGGTG	AGATCGGGGGTGGTGGGGGTGCAACCGGCCCCACTCCCGGTGTCGGTTGTTGG
GGTTCGGTTGCGCCGGGACCCTGTGGTG	GTATCGGTAGAGGTGGTCCAGCAGTTGCGTCGGGGGCCGGGATTCCT
GGGGGGGTGGCAACAGGAGGCGGAGGTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_083896809.1|5528499_5538234_+|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173789
NC_019693.1|WP_015150468.1|5526306_5527668_-|putative-calcium-binding-protein	unknown	unknown	gnl|CDD|349398
NC_019693.1|WP_015150470.1|5538576_5539479_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150456.1|5504042_5504594_+|hypothetical-protein	unknown	unknown	gnl|CDD|379226
NC_019693.1|WP_015150466.1|5521284_5522193_+|DUF1822-family-protein	unknown	unknown	gnl|CDD|370155
NC_019693.1|WP_015150472.1|5544830_5547686_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|227328
NC_019693.1|WP_015150457.1|5504869_5505082_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150471.1|5540910_5544879_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|225387
NC_019693.1|WP_015150459.1|5505859_5507821_+|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|236848
NC_019693.1|WP_156823923.1|5525809_5526028_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150467.1|5522220_5524044_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NC_019693.1|WP_015150465.1|5520622_5521261_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150463.1|5517903_5518665_+|hypothetical-protein	unknown	unknown	gnl|CDD|275293
NC_019693.1|WP_015150455.1|5501771_5503643_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150460.1|5509103_5511002_+|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|274362
NC_019693.1|WP_156823924.1|5538302_5538494_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823922.1|5511766_5511907_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150462.1|5511997_5517796_+|DUF4114-domain-containing-protein	unknown	unknown	gnl|CDD|238004
NC_019693.1|WP_015150461.1|5511121_5511349_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150458.1|5505279_5505483_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015150459.1|5505859_5507821_+|HAMP-domain-containing-protein	gnl|CDD|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	2.64819e-56
NC_019693.1|WP_015150456.1|5504042_5504594_+|hypothetical-protein	gnl|CDD|379226	pfam13505, OMP_b-brl, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	0.000306843
NC_019693.1|WP_015150467.1|5522220_5524044_+|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	8.1001e-11
NC_019693.1|WP_083896809.1|5528499_5538234_+|S8-family-serine-peptidase	gnl|CDD|173789	cd04059, Peptidases_S8_Protein_convertases_Kexins_Furin-like, Peptidase S8 family domain in Protein convertases. Protein convertases, whose members include furins and kexins, are members of the peptidase S8 or Subtilase clan of proteases. They have an Asp/His/Ser catalytic triad that is not homologous to trypsin. Kexins are involved in the activation of peptide hormones, growth factors, and viral proteins. Furin cleaves cell surface vasoactive peptides and proteins involved in cardiovascular tissue remodeling in the TGN, at cell surface, or in endosomes but rarely in the ER. Furin also plays a key role in blood pressure regulation though the activation of transforming growth factor (TGF)-beta. High specificity is seen for cleavage after dibasic (Lys-Arg or Arg-Arg) or multiple basic residues in protein convertases. There is also strong sequence conservation.	8.87911e-73
NC_019693.1|WP_015150463.1|5517903_5518665_+|hypothetical-protein	gnl|CDD|275293	TIGR04500, PpiC_rel_mature, putative peptide maturation system protein. Members of this protein family have a novel N-terminal sequence region. Close homologs to the C-terminal region of this protein score well to PpiC-type peptidyl-prolyl cis-trans isomerase models (see pfam00639), yet no sequence within the family scores well to such models, suggesting origin within a branch of the PpiC family but subsequent neofunctionalization with a rapid change of sequence. The genome context for members always includes an ATP-grasp enzyme associated with peptide modification and a short polypeptide likely to be the modification target.	6.24158e-11
NC_019693.1|WP_015150471.1|5540910_5544879_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl|CDD|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	3.5206e-97
NC_019693.1|WP_015150460.1|5509103_5511002_+|HAMP-domain-containing-protein	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	7.59181e-52
NC_019693.1|WP_015150472.1|5544830_5547686_+|CHAT-domain-containing-protein	gnl|CDD|227328	COG4995, COG4995, Uncharacterized protein conserved in bacteria [Function unknown].	1.85514e-78
NC_019693.1|WP_015150462.1|5511997_5517796_+|DUF4114-domain-containing-protein	gnl|CDD|238004	cd00044, CysPc, Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.	3.86039e-26
NC_019693.1|WP_015150466.1|5521284_5522193_+|DUF1822-family-protein	gnl|CDD|370155	pfam08852, DUF1822, Protein of unknown function (DUF1822). This family of proteins are functionally uncharacterized.	9.73778e-53
NC_019693.1|WP_015150468.1|5526306_5527668_-|putative-calcium-binding-protein	gnl|CDD|349398	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins. Little is known about bacterial and archaeal members of the CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family. The wider family of CAP domain containing proteins includes plant pathogenesis-related protein 1 (PR-1), cysteine-rich secretory proteins (CRISPs), and allergen 5 from vespid venom, among others. Studies of eukaryotic proteins show that CAP domains have several functions, including the binding of cholesterol, lipids and heparan sulfate. This group includes Borrelia burgdorferi outer surface protein BB0689, which does not bind to cholesterol, lipids, or heparan sulfate, and whose function is unknown.	3.93341e-22

Protein sequences

>NC_019693.1|WP_015150463.1|5517903_5518665_+|hypothetical-protein
MKVSQTVDLMKIGTDTISLQEALSYLKQSGQFGQFVSTVLREYIIEREIQILEFCPSQTEIEQFLLDFRIQNRIIESQAFEQWLFQNQLTYEQFRERSLKGLNFQKLREQVVQGKVEAFFAENSRLFDRLVLSRLVVEGPNLSHKIGEMLNQDPQQFKALVGEYSIAEDRVLDGRMGVFPWQELPPQLKSELDGKSPGDIVGPIVVDGLFCFFKIDQILEAKLNDTICQEIENRLFEEWLRGKMQGNNIQMLV
>NC_019693.1|WP_015150462.1|5511997_5517796_+|DUF4114-domain-containing-protein
MFNLFFGLQKRPQANGFQSPSKRYQGPAMRLEEMRTPTGLVLDDTETTDYSGFVTDSDLDFEFPSEESDIGEELPGEELDPESLDFAENSSTETNSAEEDFEDLPYFDITESTDAEPEESSSDETAQFVSDSADSSNSTNPKLEELDWIESDGSSHENIGDESELNPDQELLPESSEEAVEEAVLTTPTEEIDPEVEEPDIVSQLPETDTEETSISDEIETLTPQSDPIGTDEIEAEDSSFFAELEEVEESELDSSIYEPSDSVVTETDEGIASEADSSIGDSESEPFVNEETETNSNADELEDSAILETEETIDDSETEENDLVANAELSNLKPQFESGTFRVGETGEVEVDFLFDGGAYKGEVAIVSLSGMEGLDPTSQEFFLESISRAASNSELGYIIINDSIEGARFSGDLGEADYNSGEYQGVKSFAMRPGDEFFLMLVPNGTLQQVLDNPNAGGAVRPLFSLATANPEDGYHFGQIADIIGDGSAFAWEDIRIDGGSDRDYNDIVLQFRGATGKAALMDDVVAAGKDWRGTELGQELINYVNSQQPEEPIAETPEEPVAETPEEPQEPQEPVAETPEEPQEPVAETPEEPQEPEEPVAETPEEPQEPEEPVAETPEEPQEPVAETPEEPEEPVAETPEEPQEPVAETPEEPQEPEAETPEEPQEPEAETPEEPQEPEEPVSMERPFTEQEIVKDDWERSTAYAEGETEPDPDVPDTVDPATVINLGNLNRDAFLENQLNSQEDGLGETGVTSTNFSESSVEALPQDGFGNVSNQAPVVTTYNQTLNPGTSIAGTDLFTVYDPDGDAIQWYWLYDYNSNMANSSTSGYFTLNGIKQNNGFSINESQLATVEFVAGSESGTDKIYIQAYDGTTWSESSLVMVTTELPNQAPVVSLNSHPYFAKPSVDTALDFFTVTDPDGDPITLYAFSTSSVYGRNGYLTVDGVAQDHSWFTVEADQLDQVNFVSTTNAGYARILVKAYDGQAWSDPVQTTVNIMRSVTADDFTLEVGSSISVQDFLVEDTDTPFITRYWFEDTNKSSTSGYFTVNGIKQNGTYFTVDADQLDTVHFVAGAESGDDGVRIRPMTERGSWSGHFTNLTITTEPANQVPEVTTYNQTLNPGTSLAASEFFTVYDADGDEIEMYYFYDINGNSTSGYFTLNGVEQTGAFTVTASQLGMVQFVAGSQAATDSVYIYAYDGKIWSGYSNVILTTEVVNHAPVVTTYNQTLNPGTSLSASDFFSVYDADGDAIEWYYFYDTNSNSTSGYFTLNGVEQTSGFAVTASQLGMVQFVAGSQAATDPLYVYAHDGKTWSEYSTLTLTTEVLNRAPEVTTYNQTVNRSESIIPYFTVTDADGDTITRYALYDGNTHANSGYFTIDGVKQEAGQIIYVDANQLSQVEFIGGASATTEQLYIAASDGKAWSSWSNYTVQTQPGSTPTVVINNATVDVNTSTSLTLNVSDLDGDTVTRYEFFDSNAQSTSGYFTVNGVQQEAGKSFFVDADQLHTVQFIGGAAAGSDRIAIRATDGIDGWGNWSYAEFTTEETVTYDWFDLNIKDTTIRALARSNFQDGILCRHDMIDIFDSAKNNGFVSTDQLADLQLLSSDVTYIQMADHARILSQKIAHGDITNQQYLGQSLGNLYEESSATHLQKLIDKHFFGKDLPGLTGDYAYGKANDATYKFVQGELFQDGIDYTDVRQGYLGDCYYLAALAGIAMQDSQKIEEMFIDNGDGTYTVRFFNNGTADYVTVNRLLPTLDSGQFIFASVGGTLQQSWWSANPYYVQNTYNNVNNELWVALAEKAYAQINEAAWIGQDGTNSYKGIEEGRAQVASEHIAEVEGKYHDFSHSSVAAAIAAFTAGSAVFFSSDKNQHGTLIGSDKLVGGHAYLLTSYDSVNKTVTLFNPWNSGNSYDKDGYLTVSWNEVSTYFYAWREAS
>NC_019693.1|WP_156823922.1|5511766_5511907_-|hypothetical-protein
MNSAIARCIRTNAIAPESPSFVSYLFIREAEAKLCTDHASPEENFT
>NC_019693.1|WP_015150461.1|5511121_5511349_-|hypothetical-protein
MTLLIALFIVGWVAVAVLGTQAYFRGEQSKPIHERNWRSDSFETLAESITGTDIDYSKRVPAFEVDAYTSSNLPS
>NC_019693.1|WP_015150460.1|5509103_5511002_+|HAMP-domain-containing-protein
MVIFNRKKGLSLASKLTLAMTTLAIVTVGSVTGLFLRRTQQNFRSELENQAEIVLTTLAITTAHALQNQQADFLEEILEQLGSEQILVVGRIYGADGRIVADIYNDDIWRYNTEPDAFGVILVNSNQTVFEWQSDRLIAGKVVIREEQLLGAVSIGLSTAELWEKMAAVRNQGIIAALSASVAGTLFALLLARSITRPLQEMTAATERLAEGDLDQTIVVGSHDELFLLAESFNSMTEQLKTSIATLEERAEALHQSEAKNRALLEAIPDLMLQFSQDGTFMDFKGGRGDTLLRPAGDLLTQNLDSILPPGLARIYLKYVQIALETDDIQVFEYDWFINETRRYFEVRMVVSGHQQVLAIIRDITANKLTQLELEQAKEAAEAASHAKSMFLATMSHELRTPLNAILGYSDLLRDQAHEEGLEEFVPDLDQIHQSGLNLLTIISDILDISKIEAGHTKLYLERFNMAALIAEVQSHTKLSILKNSNQLEVKYGDELGTMTADRTKVKQVLLNLLSNAAKFTQNGQITFSVDRIEAVTPNGDPDPNPDAAIFVFTVTDTGIGMTPEQIQKIFQPFVQADEKYTRKYGGTGLGLAIGQNFCHMMGGSITVESQPGEGSSFTCRLPAVVHNPQGS
>NC_019693.1|WP_015150459.1|5505859_5507821_+|HAMP-domain-containing-protein
MGKFIGKKRSLTTQLTVSVTTLTLVAMATITAISIWSQQQTLRKQLERQADQLLEAISISVGNALTGGNEQFLQTLVEENQQRGIALSTRIYQTDGEVIAEDSPEAGASPEAEPFVGQLLETNRTLFRWQDNRLIAGKAVIVEGTPVAALRIELSKALLDQQMFVASATGLLAILITGFVAVIVARKLAQSITGPLYQLGSATEGIAEGDFTQTIEIPAYEEIGLLTHSFNTMSDRLRELFENMADRTADLHQSEAKNVALLMAIPDLMFGFSQDGTFIDYKGGRGDTILKPQGELLQKSVELVFPPELADLYLKYVNSALQTRDIQVFEYEWFINGKRRHFEARFAVCGEDEVLAIVRDITENKLAQFELQQAKEAAEAANYAKSVFLANMSHELRTPLNAIIGYTDLLEEEAEDLGYEDFISDLNKIRQAGKNLMGIISDVLDISKLEAGKMTLCLETFDISTLLLEVQTTVLPLVQKNGNTLEIQCPRNMGSMYADRTKVKQVLLNLLSNAAKFTESGMISMSVKKIRKEKTVQDEATHSPLLSPAENSPESEQVHATEYAIFRVKDTGIGITPEQKQHIFKAFAQADPSTTRKYGGTGLGLAIGQRFCKLMGGKIFVDSQADGGSTFTVCLPVIVKPPKNVSWSVEKYN
>NC_019693.1|WP_015150458.1|5505279_5505483_+|hypothetical-protein
MNGQQTPSTHEPIQSSEELEKAFQELGRAFTVYWAWKATDLLDRQPTSARCHDTPHRTPPDNPGDSG
>NC_019693.1|WP_015150457.1|5504869_5505082_+|hypothetical-protein
MSETKPKQVDFSNAKEPPKSIDSEVDTSAENPNLDPKFNPSQEQEEPEKQPDGIPPGERMIQQTWMRGGR
>NC_019693.1|WP_015150456.1|5504042_5504594_+|hypothetical-protein
MKRILQSVVTLSALSVVMMIPALLSSSAAHAEGLQTLTGKQGMAGHYLGAGLGGNLHNWDEGQGSESYGGNVQGRYQVPNSAFSVRGSALINNNAAALVPMLSVDVPVTNNANLYFGGGYSFISERGQQTALGNQDALTVATGVEAVVQENIVLFGDAKVAFDAYRNTDQAAFSLLVGAGYRF
>NC_019693.1|WP_015150455.1|5501771_5503643_+|hypothetical-protein
MKSDKFDLVRSNELEPLNGSHRLSASLSDDLLLIQWLEKNPDYVGLVKRSRRQGWFWNLYYSLNPKPPIVYVLGFLQANPRHFDGEAFVPRDVRRDSEITADIVSGATLINAITNFPILLFAFKGLGNIWVAPVASFVLNLIVLNWTNLAGTATAGNRPGKKYWAQVGFAGFLLMSILQSFVAGIGSELINNRPALSYKLAEELIEEHDRKIRQVEPDTDAYERTFAQCQENLQLLSQIPRTDPRWDSLYVETNGSVADRERDWSRVPEENLPLCQKADRIRTETFAVREDWEEKLKTRSELGNDLIFLNRELPLVFSRYFNEYGEITSGVEEVRLASSNFFGNLFALNFSRLGFSLFFFMLSTITSITACYITVAHARGRNTKISHNPEVEAAVREWLETIRQMNLNRHRPNPSKEERYEERLIARFTSEYRKTGICDYPVLEGIAYRAHQGTLFLPEQQQLISDEIDRTLDDIYKAVSALEYKFCDLQKFVAMSDPEIMQKTLKVEMLMKSDLKLLFKALHYLLDKAHKYAVSNYGQWEYLESDDAEKARKLIKQIVKIRKALNREAHVNWVMSKPTEFGRSKACQRVRQKLDVLPGYCYELGYITQQKLLDKVVVNPPSV
>NC_019693.1|WP_015150465.1|5520622_5521261_+|hypothetical-protein
MPERDRNRQNEEMQHYAELAQGHPPQSRERQLALTKLVGAIAGSGKLSRPRQGEFIAVYEEIYAEALSLLWLFVCENIDRYDSGRGSVMTWVNYLLDKRFIIEGIKTIVGKKGDRPLSTVEVELIPQPETLPSPSQFLEQYIEEDREGLFQSTHLKYRPDVNFQQIALARLAGVKWKTLSVDLNVTVSTLSSFYQRSLKELSAPLQMLFIDE
>NC_019693.1|WP_015150466.1|5521284_5522193_+|DUF1822-family-protein
MEMNIEQLTFTTSLIQKYHQMAQQFGQQHLTKAKSAQVYQNTLAVLSVNYYCQCLGIPTQLTASDSWNPILQSLLDIADLQLAKGGKIECLPVQVDADWVEVPPEVLTDRIGYIAVEINPSQTQARLLGFTETISSNPVPLSQLQGLESFIDRLHAIPSTQRIHLSQWLHHCWDAGWKRVEDLLEVPQLELALQFRTTQTAVKGGKLLDLNSTGDSVALLVGIKPTNPPEMDIWVEVYPIGEQTHLPRDLQVMVLDSSQVSVMQAQARSTKNIQLNFSGEPGDQFSIKLELGDVSVTEAFII
>NC_019693.1|WP_015150467.1|5522220_5524044_+|CHAT-domain-containing-protein
MAKLVVIKLEGDFHRQGFGVTLEIGTEGDRPSIELPGKLPPAPDLAIRLQQWEAKYRNLDTLRGLKPKQIFYNGSIVQRVQECRDAAKILSDCFQDWIESKDFLPLDKTLREELNRTEIVRVLIRSNQFLVQKLPWHLWDFFERYPNTELALISPSAKRVDCLKVAQNAVKILAILGHKEGIDIEIDRQILENLPDAAVTFLVEPTPEELSDRLWEDSWDILFFAGHSETQGESGRIYINPQDSLSLEELKYGLTKAVARGLQIAIFNSCDGLGLAREFAELNIPQTVVMREPVPDSVAQRFLQYFLAAFSRGESFYLAMREARERLEGLEGEFPCASWLPVICQNPTMVPPSWADLRGKSREQERVSPLSPLPQIPEKKLHSRPSYSVRFVTGIILASLGIISWQKFAPTLATRLNNSGMDSYGIGDLSDYWKKLDLAWVFDPYNPTVYYNKAWSCEDVLDYDCARVHYQKAARLGSAAAYNQLGSISMKVDEDYHTALHFFTQGLQLATQDRDKFALYKNLGWTQLKLGREVEAGDSLEMALNLHQNYASPYCLLAQVRENLGQVPEAIALWEECQTLANLQKPEEYLWLGMAKQRLSEIRPPQN
>NC_019693.1|WP_156823923.1|5525809_5526028_-|hypothetical-protein
MNNSIFLNSLFLGLIVMGQPTSTLEVFSTALGSNTGRIGMEISTARNSSEICFDEKGNKYHCASFHESTQFF
>NC_019693.1|WP_015150468.1|5526306_5527668_-|putative-calcium-binding-protein
MSTFSPTEAPYLSSLEKGIIDEVNRARTNPSAYAAYLEQIRNSLTTIEGPSVITETIQFLRSQAPLAPVELSQGMTMAARDHVNDKGPQGLMGHQGTDGSTVSDRLNRYGTWQTGAAENISYGKKTARDIVLQLLIDDNVSSRGHRINIFNPQYRFIGIDSGPHGQWGTMSVMKLAGNYTDASSLPTLPAAVPDAQIAFNPSRGTPEIGTPSGVTDFTNLGEFFTLSDASDRINLAEWPDAMGKSVLALNGNDTVIGTTGNDEINGNRGNDDIQGGMGTDYIRGGKDFDVIWGEDGDDILNGNNNDDTVYGGAGDDIVRGGKDNDILFGEAGNDFLVGDFGQDSLIGGPGSDVFVLRSDSQDGLSNTSRFVTEVDIIADFNPNEGDRIGLNNGLSFSSLTFEELDINNGASQQAIALRIGATGDYLGLVLNISSSELQVPDNFVTADQRLMLG
>NC_019693.1|WP_083896809.1|5528499_5538234_+|S8-family-serine-peptidase
MMSDNLLWNESGSFSGLLSEENQNQTFMNLEGGEQDYEAIAPLIQNEPLAVEDPSLNYNQEETETQLKQAVDQLINQSETDFILGSSPENSLQSLEPHEIKAESLITDEDPLLGSEISTGDSDSLIGGEQTTETAESPVLDSSQTSENSTQSSDSAVEENLPYQSGFFTITDPSGQVTFDHLFDGGGYSHGELAIFSLAGLEPNQLSWNELVKEAARRALSNSEEGYVVISDSQEGARFSGELGEPDYNRGEYLGVKSFQMRPGDTFGVMLVPNGSVTELWENPQLGGAKKPIFSMSLENPNNIEQFSQVVDPNVFQMADVLGDGHTFALEDIRILNNNSDQDYNDIIFQVRGATADAIHLDRLLEGRLFKKDWRELELGQSIVGYAELTVAAANDLLTEPLTPDLSDPVRYGVERAENLNNYDPELLAAQTEWVIWFAPNPYIQVSQIATLLGADVVNATGHIEHTYIWKFPEAISAQEVQQRLADLIGGDFAYPLVPIELKKPQFIPDDSLLKDQWHLPDTSEVNGNTSEGANAINAWDWSTGKGVVIAIVDDGVQQDHPDLIERFKYAAENGLNLDLNDIEDPGGDPVFAQVETTFATSNRVEFSDGPVESIQDLFGLSNRLRWMDEEMSWNELFGLSNRIRWSDEEELSWNKLFGLSNRIRWSEDPQQFLEGLFGLSNRIRWADDSEMNLEDLFGLSNRLRWAEDAELLQQDFAGLGDRTLILKDDDGQDEEVSLEELFGLSNRIRWSSEPEKFLEELFGLSNRIRWSNDSEVTVEQLFGLSNRIRWSEDPQLLLEDLFGLSNRIRWSDEALEANWEEIFNQANSLQNVSDPEEFLTALFGEGDWIEWEDGTAISWDELFGLSNRIRWSSEPELFWDSLFGLSNRIRWSEDPVLFWDTLFGMSNRVRWMEDSELSWDWTELFGLSNRIRWSEDAGFFLEDLFGLSNRIRWSDDRPVDWSELVSNIHEILAAEPEERAELWETWYGGENALIWSSDNIPVSWQELGAVVTDIDWSKTLDESWSWKQLFGLSNRIRWSEDAPPPPYHPPGMHGTAVAGKAGAAGTQHGGVSGGAPDADLVMIRLTADKVTDEKIATAISHAYHGIDIYNNSWKPADAFVSPALSLAALENNALEGRDGLGNIIIFAGGNDGWDGGDVNYNPFANSRYVIPVAAIDYQGQQSWYSEPGASLLVSASSSSAYGDGTSVGITTTDLVGEQGYSDGNYTDRFGGTSSAAPLVSGIVALMLEANPDLTWRDVQHILVETTQKNDPNHSDWVQNGAGLWVNHSYGFGAVDATLATQAAMNWEFVQPEIAITSGAIDIVGLDAEGNIDHTIRDRLPQNNPTGIEIPDFDATGITDSVTIYEDIKIEKIEIVFDAKGLYRGDLEIVLIAPDGTESVLAQPRFDDGTAYENWVFTSTRHWGESSLGEWQLQVRDLMSGDVGTWNGWKLNFYGTENDATTVSVTATDADATEDGNAGQLVFTRDGGDISKALMAQYSIAGTATNGTDYQELTGTVIFEPGQTKVTLGVVPFHDYELEGNETVEITLIDGIGYSLGTEISDTVTIGDSTITDHYGSFVYVNPANGHLYLLSEPDTWLGAQNQAEALGGNLVSINTADEQQWIVDTFGTQQVFHIGLTDSEMYGNEEGNFKWVNGDPITYENWKEGEPNNTPFLPEGEDFSVINQHVDGKWNDRIHLGNFPGIIEIDPATLDQPIVNIMVTDSLAGEDGNAGQIVFQRIGNLDQNLSVNYTFGGDVTNGSDVQTLSGNIIIPAGQTLVTLPIIALPDDEIEGNETLVVNLAEGDYEIGTKPSGHIIITDQDPINRLYHELFARDGDSGGVAYWRNLWQNGLSLSEVRVLMVNEGIYAESGTRINQIYQDIEGRAATTEEISYWQDRLGTNTTLSQVRQELEGADLIDTNSYVYTNPTTGNRYFLTTPDTWLGAQEQAQALGGNLVTINSADENQWLLDTFGSGRMWIGLNDSPIYGNTEGNHQWVSGEAIADASWWNAATDNTLHTSEGEDFSETNFVGTPGLWNDMPSQQNFLGRGIVEISYTPSYNWMWTQFGEDLHTGDNSVRLPSLPNTENARNEFVANLINVETIDFENFAHDDTLNTLNFGNTTATLSGNLKVQTLPAGTDGGMFPTSGDNYLLSSNDESFTINFNSPQSAFGFTVIDAEGDPFVLTLHREDGTTSELTIPVTASWPANSGSALFFGVTDTNTPFTGVTVRKPGDTERIGVDDLIIGQVKPNNTSTPTPPNQTLNLTYTEDTPLNLSGIVVSDPDGETTVTLTLSNPAAGVLTTGIGTGQYNATTGVWTANGAVADVNAALADLQFVPTANFNQDVSIALSITDDIAAPLTGAIALQGIPVNDAPTVTTSNLTLTGATENAGFTVTHADLVAATGATDIDGDPLTFRIQTVGSDIPTKNGQPVEAGVTTLSAGEAIVWTPTTVGNAQPAFTATLTDGKVTVATPVTVSIDVNPVTVSIEATDPDATEGGDTGEFTFTRTGSTAESLIVTYGIDTNGFWSSPVATNGSDYELLTGSIEIPVGASSVTLPIITLDDSEAEWPERVKVYLTQNDGYEIGANSHDEVKIWDNETPEVQLYVSSSGFYDASEPYLAGRFLVRRIGSLADPLTVNYSIAGTATPGTDYTNPGMDYNALTGNITIPANKHDIYIIIAPIDDSEEEGVETIDITLTPDTNYTIEPGAETKTINLWDNENRSTVSISVTDSTATEGADSAQFTITRTGDVSEAVTVYYQVSGDWHNSASNGIDYDFITDSINFEPGQTSRTIDINPIDDDIAEVTETVNITLKSDSGYNLSTMRSGKVIIFDNEAPTVEWQQQFGTSAEDVAKSVAVDSAGNTYTVGHTSGNLDGTNAGGSDAFIVKRDSNGSELWQIQLGTAGNDEVKQIAVDSADNLYVLGWSGDPSNSWIAKYDSNGTQQWQKPLGSAGYDITNGALTLGNDGSLYVTGRTTGDIDGTNQGATDTWVGKYDSDGIQTWVKQLGTTDEDEALGIAVDNNNNVYITGETKGSLAGTREGDGDAWVAQLDSSGNLQWQTQLGTTAVDIARSVAVDNNGHVYLGGQTFGWLGETYQGHPRNWVGDESARLAALQGDKYGLGGTYYGNGDAWVAQLDSTTGSVNWKRLLGTTNADSGSTVVADSLGNVYLTGTTEGKLGNTQFGANDIFIAKYNIDGALQWKQQFGSDGDDIVNDMILDITGIYLVGDTTGDLDGSNLGEKDAWILKLS
>NC_019693.1|WP_156823924.1|5538302_5538494_+|hypothetical-protein
MDSNSFLTIAIGPVDLDGRSCWCWVRDRLPASIDDPIIQRELREVLFQEWLQKQLKETTLRLD
>NC_019693.1|WP_015150470.1|5538576_5539479_+|hypothetical-protein
MTRFIHDQFAKQYLEELLSPFGTVETGKTIAAEVQEVDVLFIANPESNRDRSSLGLLGQIAGNQSIFEPFRNAVQPKQIRSCLAKLYAIQSNEERKANRDNTPLPEEEVITGWILTPTASSSLLDYFGATEDPIIGVKGVYSLARGLKMGLIAIHQLPVNPETLSLRLLGKGRVQQQAVNEIQGLPDDNPWKLAALELLYNLRTILEVRQDLEPDDQELIMELSPLYLQRLEDATQRGRQEGNQQGQRLMIESMLQVKFGEVDAELAQIIDPLIELTPLERTQLIMQLSRDEILTRFLNN
>NC_019693.1|WP_015150471.1|5540910_5544879_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MTLFMKPLLFPVALAGSLTLCWFAIVPTRTSAQIVPDRTLPENSRVTPDDNTFIIEGGTSTTGGTLFHSFEEFSVPTNTEALFNNTDQINQILTRITGASISNIDGILRANGNANLFFLNPNGIVFGPNARLELGGSFLATTGDRFVFADGSFFSASNPETLPLLTVNAPIGLQFGTTSGPINVLGIGHNLVPDELGAVDRSNRSDGLQVNPGNTLAILGSSVTLDGGNLIAESGRIEVGSVSAGSEIKLNSQEQGLIFDYQNVRGFQDVQLTEKASIDASGPGGGDIRVHGRNINLNDFSVVLSLTEGNESGQTLQVNASDSIKLNELSAILAETYGTGIGSTLNINTGLLLIENGSTISAGVNDGEPGNVLSINVRELILENGGQISASSFFENGKAGDIHIRASDSITASGEGEDISEEMRASGIFANQNDPLGTRPGGNITLETRNLTVDSGAQIAVGTIGFGQAGTLRVTALDSIELAGRAQDPEFSSGLFASTLGFGNAGNLIIETSRLIVRDGAVISVKGQTLNDLEMVWGIEDIDNLPEEALDFFGIENPTELALGQAGNLTINSPLILLNEQGIIRATTVAGDNANIQITTNNLQLRRGSNITTDASRLATGGNITIDTQTLVLGENSNITARATDGRGGNIQVNTTADIRSFDSAIDASSQRGIDGVVAINRPEVDPAAALVELEEDRINPVALVPRGCDVGSSDNSSRFIVSGWGGLPPSPREPRSGGNFIDNLDPLPARNYEGSGENLGNFSLGEAVPVQRISEASNWQLNEQGEVVLIAAVEKSSPDLPGIGCDGEALSPGLKNVETAASGIPESITVDRFNVVGNSVFSEAEVSQVLSPYTNRSLSFADLREARSAITNLYVEAGYITTGAYLPPQTVRENTVEIAVVPGMLREIQVNSNRLHNYVHDRLMVAIGNEPVNVNRIVEALRLLRLDPLIQEVQGELRAVPIPGQNILEVNIIEASPFSGTQLVLDNRRSPGVSTFRQQVQGNYNNLLGLGDRLFFSYARTEGSNTWEGSYIVPITPRNTTLGFRYSNGNSQIVESPFDRLDIEANSRLYELTLRQPFQRATPEYTREFALGLTASRQASETSLLGDRFPLSAGANNNGELRVSALRFFQDWTQRQPEQVLALRSTFSLGVDAFDATVNNNAPDSRFFAWRGQGQWVRSFGRDTLLFVRGDVQLSPDNLVSFEQIGLGGLDTVRGYRQDTLLTDNGVLGSVELRLPVFRFAGGNGLVQIAPFLDVGTGWNSAGQANPNTTSLVSLGLGLQLELGNQLTARLDFGKPLVDINSRNRTWQENGIHFSVKYNPF
>NC_019693.1|WP_015150472.1|5544830_5547686_+|CHAT-domain-containing-protein
MARKWHPFFGKVQSFLNRGWKFILISIFATITILNLQGGSPVLAYQPWGETVAQTPSFDGEMRLEEGSRFYENLRFAEAETAWRASVGLLSGEEKALGLSYLALAQLRQSKLDEADISIQESLRLLNQVTTPGTSERNQIIHARILTTAAQVNLARNQPELAAHALEQFAEATTIYEKLNQQEWVIASQINQAQAMQQLGMYREALKTLKNLENLILHHSDSEIPLSGLLSLGKTYRAIGVLDQSYCVLEAGKENPEIALELGNTAQAIGKRIKDQLDSVNEKTSEPIFTTEQGVENCTIPFKDIPLISAWDFYEKAQDFYQQSWNSPAVKPETQVQGMLNTLSLALDLKDAKELEEETKSNLERQAHELPPQVLQLIEILPSLNREKVYDRIHLARSLTRLNLEELSQNQLETAIAEAQELADQRAQAYAIGELGWMKQQQGNWTEAEQWTRQAMAITPPDAIDIRYQWEWQLGQILKEEGRTEEAIRHYTEAVDLLQRVRQNLVAIAAGMGEMNADLQFDFRDRVEPVYRELVGLLLDSQGNEVTSQDHIQTALGVIELLQVAELENFLQCDLQPEPQVQLARSVAEAKQKVAEKLNAIHQKKPDYAVIYPIIIQDKLEVILGLPGTPLVHYSNPSSDNIKKILADFRRQLIIPRDFEAVKNQSFQLYKMLINPFKSKIDNKSLLFILDVPLQSVPMGALYNKITEKYLIQTHTIRMTSSLQLLQIDAEKHPITEVLTAGIAQPRTERNIPFSSLDHVEQELDDIRKHFPGSQKLFEEKFTQSNLEQALSHQTFPAIHLATHGHFSSQRYLTFLLDGQTIIEVADFKRLFAEPSYLTTNPIQLLVLSACQTAQGDRKSALGIAGLTVSGQINNTIASLWSVKDQSTARLMNKFYEKLMEFSSPDLSQSDRTALALQEAQKSMIEEQESILRRRHHPSSWSPFILLSNAL

Crispr_ID: NC_019693_57

• CRISPR_ID: NC_019693_57
• CRISPR_location: 5530723-5530935
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_019693_57

Consensus_repeat	Method
TTATTCGGACTCTCCAATCGGATTCGCTGGTC	CRISPRCasFinder
TTATTCGGACTCTCCAATCGGATTCGCTGGTC	CRT

spacers of NC_019693_57

>57.1|5530755|28|NC_019693|CRISPRCasFinder,CRT
CTCGGAACCTGAGAAATTTTTAGAAGAA
>57.2|5530815|28|NC_019693|CRISPRCasFinder,CRT
CAATGATAGTGAAGTCACCGTCGAACAG
>57.3|5530875|28|NC_019693|CRISPRCasFinder,CRT
TGAAGACCCGCAACTCTTATTAGAGGAT

CRISPR arrays and Neighbor proteins around NC_019693_57

CRISPR arrays

The CRISPR arrays of NC_019693_57

>merge|NC_019693|57|5530723-5530935|CRISPRCasFinder,CRT
TTATTCGGACTCTCCAATCGGATTCGCTGGTCCTCGGAACCTGAGAAATTTTTAGAAGAATTATTCGGACTCTCCAATCGGATTCGCTGGTCCAATGATAGTGAAGTCACCGTCGAACAGTTATTCGGACTCTCCAATCGGATTCGCTGGTCTGAAGACCCGCAACTCTTATTAGAGGATTTATTTGGACTCTCTAACCGAATTCGCTGGTCT

>NC_019693|57|55|5530723-5530935|CRISPRCasFinder
TTATTCGGACTCTCCAATCGGATTCGCTGGTC	CTCGGAACCTGAGAAATTTTTAGAAGAA
TTATTCGGACTCTCCAATCGGATTCGCTGGTC	CAATGATAGTGAAGTCACCGTCGAACAG
TTATTCGGACTCTCCAATCGGATTCGCTGGTC	TGAAGACCCGCAACTCTTATTAGAGGAT
TTATTTGGACTCTCTAACCGAATTCGCTGGTCT

>NC_019693|57|4|5530723-5530934|CRT
TTATTCGGACTCTCCAATCGGATTCGCTGGTC	CTCGGAACCTGAGAAATTTTTAGAAGAA
TTATTCGGACTCTCCAATCGGATTCGCTGGTC	CAATGATAGTGAAGTCACCGTCGAACAG
TTATTCGGACTCTCCAATCGGATTCGCTGGTC	TGAAGACCCGCAACTCTTATTAGAGGAT
TTATTTGGACTCTCTAACCGAATTCGCTGGTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015150468.1|5526306_5527668_-|putative-calcium-binding-protein	unknown	unknown	gnl|CDD|349398
NC_019693.1|WP_015150470.1|5538576_5539479_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150475.1|5550926_5552138_-|DUF1822-family-protein	unknown	unknown	gnl|CDD|370155
NC_019693.1|WP_015150473.1|5547798_5548524_-|DUF928-domain-containing-protein	unknown	unknown	gnl|CDD|368720
NC_019693.1|WP_015150472.1|5544830_5547686_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|227328
NC_019693.1|WP_015150466.1|5521284_5522193_+|DUF1822-family-protein	unknown	unknown	gnl|CDD|370155
NC_019693.1|WP_015150471.1|5540910_5544879_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|225387
NC_019693.1|WP_015150476.1|5552163_5554281_-|hypothetical-protein	unknown	unknown	gnl|CDD|100119
NC_019693.1|WP_156823925.1|5555064_5555265_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150467.1|5522220_5524044_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NC_019693.1|WP_015150464.1|5518751_5520191_-|hypothetical-protein	unknown	unknown	gnl|CDD|223021
NC_019693.1|WP_015150465.1|5520622_5521261_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823923.1|5525809_5526028_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150477.1|5554384_5554945_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823924.1|5538302_5538494_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823922.1|5511766_5511907_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150462.1|5511997_5517796_+|DUF4114-domain-containing-protein	unknown	unknown	gnl|CDD|238004
NC_019693.1|WP_015150461.1|5511121_5511349_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150474.1|5548523_5550887_-|CHASE2-domain-containing-protein	unknown	unknown	gnl|CDD|226703
NC_019693.1|WP_015150463.1|5517903_5518665_+|hypothetical-protein	unknown	unknown	gnl|CDD|275293

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015150468.1|5526306_5527668_-|putative-calcium-binding-protein	gnl|CDD|349398	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins. Little is known about bacterial and archaeal members of the CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family. The wider family of CAP domain containing proteins includes plant pathogenesis-related protein 1 (PR-1), cysteine-rich secretory proteins (CRISPs), and allergen 5 from vespid venom, among others. Studies of eukaryotic proteins show that CAP domains have several functions, including the binding of cholesterol, lipids and heparan sulfate. This group includes Borrelia burgdorferi outer surface protein BB0689, which does not bind to cholesterol, lipids, or heparan sulfate, and whose function is unknown.	3.93341e-22
NC_019693.1|WP_015150466.1|5521284_5522193_+|DUF1822-family-protein	gnl|CDD|370155	pfam08852, DUF1822, Protein of unknown function (DUF1822). This family of proteins are functionally uncharacterized.	9.73778e-53
NC_019693.1|WP_015150472.1|5544830_5547686_+|CHAT-domain-containing-protein	gnl|CDD|227328	COG4995, COG4995, Uncharacterized protein conserved in bacteria [Function unknown].	1.85514e-78
NC_019693.1|WP_015150473.1|5547798_5548524_-|DUF928-domain-containing-protein	gnl|CDD|368720	pfam06051, DUF928, Domain of Unknown Function (DUF928). Family of uncharacterized bacterial protein.	1.22085e-37
NC_019693.1|WP_015150471.1|5540910_5544879_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl|CDD|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	3.5206e-97
NC_019693.1|WP_015150476.1|5552163_5554281_-|hypothetical-protein	gnl|CDD|100119	cd06171, Sigma70_r4, Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).	0.00100418
NC_019693.1|WP_015150467.1|5522220_5524044_+|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	8.1001e-11
NC_019693.1|WP_015150464.1|5518751_5520191_-|hypothetical-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	2.9935e-17
NC_019693.1|WP_015150475.1|5550926_5552138_-|DUF1822-family-protein	gnl|CDD|370155	pfam08852, DUF1822, Protein of unknown function (DUF1822). This family of proteins are functionally uncharacterized.	2.80417e-45
NC_019693.1|WP_015150463.1|5517903_5518665_+|hypothetical-protein	gnl|CDD|275293	TIGR04500, PpiC_rel_mature, putative peptide maturation system protein. Members of this protein family have a novel N-terminal sequence region. Close homologs to the C-terminal region of this protein score well to PpiC-type peptidyl-prolyl cis-trans isomerase models (see pfam00639), yet no sequence within the family scores well to such models, suggesting origin within a branch of the PpiC family but subsequent neofunctionalization with a rapid change of sequence. The genome context for members always includes an ATP-grasp enzyme associated with peptide modification and a short polypeptide likely to be the modification target.	6.24158e-11
NC_019693.1|WP_015150462.1|5511997_5517796_+|DUF4114-domain-containing-protein	gnl|CDD|238004	cd00044, CysPc, Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.	3.86039e-26
NC_019693.1|WP_015150474.1|5548523_5550887_-|CHASE2-domain-containing-protein	gnl|CDD|226703	COG4252, COG4252, Predicted transmembrane sensor domain [Signal transduction mechanisms].	1.67732e-92

Protein sequences

>NC_019693.1|WP_015150468.1|5526306_5527668_-|putative-calcium-binding-protein
MSTFSPTEAPYLSSLEKGIIDEVNRARTNPSAYAAYLEQIRNSLTTIEGPSVITETIQFLRSQAPLAPVELSQGMTMAARDHVNDKGPQGLMGHQGTDGSTVSDRLNRYGTWQTGAAENISYGKKTARDIVLQLLIDDNVSSRGHRINIFNPQYRFIGIDSGPHGQWGTMSVMKLAGNYTDASSLPTLPAAVPDAQIAFNPSRGTPEIGTPSGVTDFTNLGEFFTLSDASDRINLAEWPDAMGKSVLALNGNDTVIGTTGNDEINGNRGNDDIQGGMGTDYIRGGKDFDVIWGEDGDDILNGNNNDDTVYGGAGDDIVRGGKDNDILFGEAGNDFLVGDFGQDSLIGGPGSDVFVLRSDSQDGLSNTSRFVTEVDIIADFNPNEGDRIGLNNGLSFSSLTFEELDINNGASQQAIALRIGATGDYLGLVLNISSSELQVPDNFVTADQRLMLG
>NC_019693.1|WP_156823923.1|5525809_5526028_-|hypothetical-protein
MNNSIFLNSLFLGLIVMGQPTSTLEVFSTALGSNTGRIGMEISTARNSSEICFDEKGNKYHCASFHESTQFF
>NC_019693.1|WP_015150467.1|5522220_5524044_+|CHAT-domain-containing-protein
MAKLVVIKLEGDFHRQGFGVTLEIGTEGDRPSIELPGKLPPAPDLAIRLQQWEAKYRNLDTLRGLKPKQIFYNGSIVQRVQECRDAAKILSDCFQDWIESKDFLPLDKTLREELNRTEIVRVLIRSNQFLVQKLPWHLWDFFERYPNTELALISPSAKRVDCLKVAQNAVKILAILGHKEGIDIEIDRQILENLPDAAVTFLVEPTPEELSDRLWEDSWDILFFAGHSETQGESGRIYINPQDSLSLEELKYGLTKAVARGLQIAIFNSCDGLGLAREFAELNIPQTVVMREPVPDSVAQRFLQYFLAAFSRGESFYLAMREARERLEGLEGEFPCASWLPVICQNPTMVPPSWADLRGKSREQERVSPLSPLPQIPEKKLHSRPSYSVRFVTGIILASLGIISWQKFAPTLATRLNNSGMDSYGIGDLSDYWKKLDLAWVFDPYNPTVYYNKAWSCEDVLDYDCARVHYQKAARLGSAAAYNQLGSISMKVDEDYHTALHFFTQGLQLATQDRDKFALYKNLGWTQLKLGREVEAGDSLEMALNLHQNYASPYCLLAQVRENLGQVPEAIALWEECQTLANLQKPEEYLWLGMAKQRLSEIRPPQN
>NC_019693.1|WP_015150466.1|5521284_5522193_+|DUF1822-family-protein
MEMNIEQLTFTTSLIQKYHQMAQQFGQQHLTKAKSAQVYQNTLAVLSVNYYCQCLGIPTQLTASDSWNPILQSLLDIADLQLAKGGKIECLPVQVDADWVEVPPEVLTDRIGYIAVEINPSQTQARLLGFTETISSNPVPLSQLQGLESFIDRLHAIPSTQRIHLSQWLHHCWDAGWKRVEDLLEVPQLELALQFRTTQTAVKGGKLLDLNSTGDSVALLVGIKPTNPPEMDIWVEVYPIGEQTHLPRDLQVMVLDSSQVSVMQAQARSTKNIQLNFSGEPGDQFSIKLELGDVSVTEAFII
>NC_019693.1|WP_015150465.1|5520622_5521261_+|hypothetical-protein
MPERDRNRQNEEMQHYAELAQGHPPQSRERQLALTKLVGAIAGSGKLSRPRQGEFIAVYEEIYAEALSLLWLFVCENIDRYDSGRGSVMTWVNYLLDKRFIIEGIKTIVGKKGDRPLSTVEVELIPQPETLPSPSQFLEQYIEEDREGLFQSTHLKYRPDVNFQQIALARLAGVKWKTLSVDLNVTVSTLSSFYQRSLKELSAPLQMLFIDE
>NC_019693.1|WP_015150464.1|5518751_5520191_-|hypothetical-protein
MEINVFDPTFYRSIHPDLSEFNDSETFDHLINHGLNEGRKFSPFLDLNVYGSINPDLATAGLTSNQQLYEHWQLFGVNEGRSFSRVFQADFYQQNAPDLQAAGLSNAELFNHFRTLGIEEGRQASPLFNVNFYLASNPDLQAAGFNNRQALDHYIVHGIPEGRMGFQVPPMIPNQPPTSPQPPPLPPGPDNPAPGATPGPFLPFPATGPEATGPQQPTPGVGPATPPTPPISLQPPGMPPFPDNPAPGATPGSPPPIPPQGPEATGPQQPTPGVGPAAPPPPPISPPPPVATPPGIPAPDATAGPPLPIPPQGPGATEPQQPTPGVGPVAPPPPPISPPPPGLTTPERPTPVAGPGPGIPIPPPPPGSTTPQRPTPVAGPAPGIPIPTPSTDNEEQEEDEITRTSQASQNYQLTPEAIHSGELRSFTAQTSWTDIFANGVASPSADMVLRETFVSPVGDNVGQMNFLSAPNYGADFLLM
>NC_019693.1|WP_015150463.1|5517903_5518665_+|hypothetical-protein
MKVSQTVDLMKIGTDTISLQEALSYLKQSGQFGQFVSTVLREYIIEREIQILEFCPSQTEIEQFLLDFRIQNRIIESQAFEQWLFQNQLTYEQFRERSLKGLNFQKLREQVVQGKVEAFFAENSRLFDRLVLSRLVVEGPNLSHKIGEMLNQDPQQFKALVGEYSIAEDRVLDGRMGVFPWQELPPQLKSELDGKSPGDIVGPIVVDGLFCFFKIDQILEAKLNDTICQEIENRLFEEWLRGKMQGNNIQMLV
>NC_019693.1|WP_015150462.1|5511997_5517796_+|DUF4114-domain-containing-protein
MFNLFFGLQKRPQANGFQSPSKRYQGPAMRLEEMRTPTGLVLDDTETTDYSGFVTDSDLDFEFPSEESDIGEELPGEELDPESLDFAENSSTETNSAEEDFEDLPYFDITESTDAEPEESSSDETAQFVSDSADSSNSTNPKLEELDWIESDGSSHENIGDESELNPDQELLPESSEEAVEEAVLTTPTEEIDPEVEEPDIVSQLPETDTEETSISDEIETLTPQSDPIGTDEIEAEDSSFFAELEEVEESELDSSIYEPSDSVVTETDEGIASEADSSIGDSESEPFVNEETETNSNADELEDSAILETEETIDDSETEENDLVANAELSNLKPQFESGTFRVGETGEVEVDFLFDGGAYKGEVAIVSLSGMEGLDPTSQEFFLESISRAASNSELGYIIINDSIEGARFSGDLGEADYNSGEYQGVKSFAMRPGDEFFLMLVPNGTLQQVLDNPNAGGAVRPLFSLATANPEDGYHFGQIADIIGDGSAFAWEDIRIDGGSDRDYNDIVLQFRGATGKAALMDDVVAAGKDWRGTELGQELINYVNSQQPEEPIAETPEEPVAETPEEPQEPQEPVAETPEEPQEPVAETPEEPQEPEEPVAETPEEPQEPEEPVAETPEEPQEPVAETPEEPEEPVAETPEEPQEPVAETPEEPQEPEAETPEEPQEPEAETPEEPQEPEEPVSMERPFTEQEIVKDDWERSTAYAEGETEPDPDVPDTVDPATVINLGNLNRDAFLENQLNSQEDGLGETGVTSTNFSESSVEALPQDGFGNVSNQAPVVTTYNQTLNPGTSIAGTDLFTVYDPDGDAIQWYWLYDYNSNMANSSTSGYFTLNGIKQNNGFSINESQLATVEFVAGSESGTDKIYIQAYDGTTWSESSLVMVTTELPNQAPVVSLNSHPYFAKPSVDTALDFFTVTDPDGDPITLYAFSTSSVYGRNGYLTVDGVAQDHSWFTVEADQLDQVNFVSTTNAGYARILVKAYDGQAWSDPVQTTVNIMRSVTADDFTLEVGSSISVQDFLVEDTDTPFITRYWFEDTNKSSTSGYFTVNGIKQNGTYFTVDADQLDTVHFVAGAESGDDGVRIRPMTERGSWSGHFTNLTITTEPANQVPEVTTYNQTLNPGTSLAASEFFTVYDADGDEIEMYYFYDINGNSTSGYFTLNGVEQTGAFTVTASQLGMVQFVAGSQAATDSVYIYAYDGKIWSGYSNVILTTEVVNHAPVVTTYNQTLNPGTSLSASDFFSVYDADGDAIEWYYFYDTNSNSTSGYFTLNGVEQTSGFAVTASQLGMVQFVAGSQAATDPLYVYAHDGKTWSEYSTLTLTTEVLNRAPEVTTYNQTVNRSESIIPYFTVTDADGDTITRYALYDGNTHANSGYFTIDGVKQEAGQIIYVDANQLSQVEFIGGASATTEQLYIAASDGKAWSSWSNYTVQTQPGSTPTVVINNATVDVNTSTSLTLNVSDLDGDTVTRYEFFDSNAQSTSGYFTVNGVQQEAGKSFFVDADQLHTVQFIGGAAAGSDRIAIRATDGIDGWGNWSYAEFTTEETVTYDWFDLNIKDTTIRALARSNFQDGILCRHDMIDIFDSAKNNGFVSTDQLADLQLLSSDVTYIQMADHARILSQKIAHGDITNQQYLGQSLGNLYEESSATHLQKLIDKHFFGKDLPGLTGDYAYGKANDATYKFVQGELFQDGIDYTDVRQGYLGDCYYLAALAGIAMQDSQKIEEMFIDNGDGTYTVRFFNNGTADYVTVNRLLPTLDSGQFIFASVGGTLQQSWWSANPYYVQNTYNNVNNELWVALAEKAYAQINEAAWIGQDGTNSYKGIEEGRAQVASEHIAEVEGKYHDFSHSSVAAAIAAFTAGSAVFFSSDKNQHGTLIGSDKLVGGHAYLLTSYDSVNKTVTLFNPWNSGNSYDKDGYLTVSWNEVSTYFYAWREAS
>NC_019693.1|WP_156823922.1|5511766_5511907_-|hypothetical-protein
MNSAIARCIRTNAIAPESPSFVSYLFIREAEAKLCTDHASPEENFT
>NC_019693.1|WP_015150461.1|5511121_5511349_-|hypothetical-protein
MTLLIALFIVGWVAVAVLGTQAYFRGEQSKPIHERNWRSDSFETLAESITGTDIDYSKRVPAFEVDAYTSSNLPS
>NC_019693.1|WP_156823924.1|5538302_5538494_+|hypothetical-protein
MDSNSFLTIAIGPVDLDGRSCWCWVRDRLPASIDDPIIQRELREVLFQEWLQKQLKETTLRLD
>NC_019693.1|WP_015150470.1|5538576_5539479_+|hypothetical-protein
MTRFIHDQFAKQYLEELLSPFGTVETGKTIAAEVQEVDVLFIANPESNRDRSSLGLLGQIAGNQSIFEPFRNAVQPKQIRSCLAKLYAIQSNEERKANRDNTPLPEEEVITGWILTPTASSSLLDYFGATEDPIIGVKGVYSLARGLKMGLIAIHQLPVNPETLSLRLLGKGRVQQQAVNEIQGLPDDNPWKLAALELLYNLRTILEVRQDLEPDDQELIMELSPLYLQRLEDATQRGRQEGNQQGQRLMIESMLQVKFGEVDAELAQIIDPLIELTPLERTQLIMQLSRDEILTRFLNN
>NC_019693.1|WP_015150471.1|5540910_5544879_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MTLFMKPLLFPVALAGSLTLCWFAIVPTRTSAQIVPDRTLPENSRVTPDDNTFIIEGGTSTTGGTLFHSFEEFSVPTNTEALFNNTDQINQILTRITGASISNIDGILRANGNANLFFLNPNGIVFGPNARLELGGSFLATTGDRFVFADGSFFSASNPETLPLLTVNAPIGLQFGTTSGPINVLGIGHNLVPDELGAVDRSNRSDGLQVNPGNTLAILGSSVTLDGGNLIAESGRIEVGSVSAGSEIKLNSQEQGLIFDYQNVRGFQDVQLTEKASIDASGPGGGDIRVHGRNINLNDFSVVLSLTEGNESGQTLQVNASDSIKLNELSAILAETYGTGIGSTLNINTGLLLIENGSTISAGVNDGEPGNVLSINVRELILENGGQISASSFFENGKAGDIHIRASDSITASGEGEDISEEMRASGIFANQNDPLGTRPGGNITLETRNLTVDSGAQIAVGTIGFGQAGTLRVTALDSIELAGRAQDPEFSSGLFASTLGFGNAGNLIIETSRLIVRDGAVISVKGQTLNDLEMVWGIEDIDNLPEEALDFFGIENPTELALGQAGNLTINSPLILLNEQGIIRATTVAGDNANIQITTNNLQLRRGSNITTDASRLATGGNITIDTQTLVLGENSNITARATDGRGGNIQVNTTADIRSFDSAIDASSQRGIDGVVAINRPEVDPAAALVELEEDRINPVALVPRGCDVGSSDNSSRFIVSGWGGLPPSPREPRSGGNFIDNLDPLPARNYEGSGENLGNFSLGEAVPVQRISEASNWQLNEQGEVVLIAAVEKSSPDLPGIGCDGEALSPGLKNVETAASGIPESITVDRFNVVGNSVFSEAEVSQVLSPYTNRSLSFADLREARSAITNLYVEAGYITTGAYLPPQTVRENTVEIAVVPGMLREIQVNSNRLHNYVHDRLMVAIGNEPVNVNRIVEALRLLRLDPLIQEVQGELRAVPIPGQNILEVNIIEASPFSGTQLVLDNRRSPGVSTFRQQVQGNYNNLLGLGDRLFFSYARTEGSNTWEGSYIVPITPRNTTLGFRYSNGNSQIVESPFDRLDIEANSRLYELTLRQPFQRATPEYTREFALGLTASRQASETSLLGDRFPLSAGANNNGELRVSALRFFQDWTQRQPEQVLALRSTFSLGVDAFDATVNNNAPDSRFFAWRGQGQWVRSFGRDTLLFVRGDVQLSPDNLVSFEQIGLGGLDTVRGYRQDTLLTDNGVLGSVELRLPVFRFAGGNGLVQIAPFLDVGTGWNSAGQANPNTTSLVSLGLGLQLELGNQLTARLDFGKPLVDINSRNRTWQENGIHFSVKYNPF
>NC_019693.1|WP_015150472.1|5544830_5547686_+|CHAT-domain-containing-protein
MARKWHPFFGKVQSFLNRGWKFILISIFATITILNLQGGSPVLAYQPWGETVAQTPSFDGEMRLEEGSRFYENLRFAEAETAWRASVGLLSGEEKALGLSYLALAQLRQSKLDEADISIQESLRLLNQVTTPGTSERNQIIHARILTTAAQVNLARNQPELAAHALEQFAEATTIYEKLNQQEWVIASQINQAQAMQQLGMYREALKTLKNLENLILHHSDSEIPLSGLLSLGKTYRAIGVLDQSYCVLEAGKENPEIALELGNTAQAIGKRIKDQLDSVNEKTSEPIFTTEQGVENCTIPFKDIPLISAWDFYEKAQDFYQQSWNSPAVKPETQVQGMLNTLSLALDLKDAKELEEETKSNLERQAHELPPQVLQLIEILPSLNREKVYDRIHLARSLTRLNLEELSQNQLETAIAEAQELADQRAQAYAIGELGWMKQQQGNWTEAEQWTRQAMAITPPDAIDIRYQWEWQLGQILKEEGRTEEAIRHYTEAVDLLQRVRQNLVAIAAGMGEMNADLQFDFRDRVEPVYRELVGLLLDSQGNEVTSQDHIQTALGVIELLQVAELENFLQCDLQPEPQVQLARSVAEAKQKVAEKLNAIHQKKPDYAVIYPIIIQDKLEVILGLPGTPLVHYSNPSSDNIKKILADFRRQLIIPRDFEAVKNQSFQLYKMLINPFKSKIDNKSLLFILDVPLQSVPMGALYNKITEKYLIQTHTIRMTSSLQLLQIDAEKHPITEVLTAGIAQPRTERNIPFSSLDHVEQELDDIRKHFPGSQKLFEEKFTQSNLEQALSHQTFPAIHLATHGHFSSQRYLTFLLDGQTIIEVADFKRLFAEPSYLTTNPIQLLVLSACQTAQGDRKSALGIAGLTVSGQINNTIASLWSVKDQSTARLMNKFYEKLMEFSSPDLSQSDRTALALQEAQKSMIEEQESILRRRHHPSSWSPFILLSNAL
>NC_019693.1|WP_015150473.1|5547798_5548524_-|DUF928-domain-containing-protein
MKTSSSGNRFGFMFLSLFMIMINLPIQVLSNENNQNSPFRGRGRPSNVIGGGSRGNCEVTAEHQTLRLTALVPAEIGGVTQRERPTWWFYSPFNQRVYSPLQAQFIVTKDDKNFLPPIDVTLPEIPGFFPVSIPPDSPLEVNKWYMWTLLVICDPQDESKHIDINGWIKRIPEHEDSEEYLRWYDPLDSIAQTQCDNPDDREALQQWEERLSSVEDQLEPWDQKVWKEVRDQRMVCHRDLN
>NC_019693.1|WP_015150474.1|5548523_5550887_-|CHASE2-domain-containing-protein
MAKLVKLSLEGDLTSGYEVELIQISEEERDGKVLIEGIGGQLPAAAEIYECYQTWQQNYEQLDRIYRGGEFRFLGVETSSNVSLAKCQQLSQILEQKINDWLDAPGFRAIADRILTYLNPEEDIRFLIKTSDYNLWQIPWSAWIFFETHPNAEVVFSSFDAKYGEKPIKATPRKNVRILSVFGSDENINTKPDQEQIERLKSVGAEPTLIIKPRADHLRNLLWDKSWDILFFAGHGDRDKDSQKGKIYLNSNEYLTPSEFKNTLKTAIVDRNLKIVFLNSCLGLEFAYELVVDFKIPVVIAMREQIPDDAAQNFLQYFLLEYADNKRPLYVAVRRAKERIAEEFQDKYPGLNWLPVVCQNPAHIPLKWGDLYNKVSVKQAAVTSLFCTLMVVLARSLGFLQPLEFMTYDWLMSLRPLESVDERIVIITIDEQDIQYQINEGFKPSLASSFSHEALDRLLQKISPYQPRVVGLDIFYNIPFEGKSLQNQIESLNQLIGICQLGDETNPNNPPIPPPPGLTTIGFVDMPVDSDGVIRRQLYGAWPPEDCPTDFSFNLRVANSYLEQELNQTNLITVTQSDNMSINQVIFPILNRRYGGYQIKGDDLSGYQGLLNYRNARFHQRSLRGILQGESDQELDELIRDRIVLIGVTRPPRSDKHPTPLINDWRDNLYGVEIQAQKISHIISAVLDGRTLFWWWGEKTENLWIASWSLMGGVLVWKLRSPLKIGLGSIIAIGILGGICFLLLLEGGWIPLFPSACGFLLTVSVLNVNPKFYQFPQKYTLKIAQAI
>NC_019693.1|WP_015150475.1|5550926_5552138_-|DUF1822-family-protein
MNANVTHPFPPIAPDELYFNLSFEMQAQAWQKSRCHSNPIARNQAYLGHLCLQGFMSWVLERFEGNSQFVEPYVNHLESLWEFIEGVPIIVGKNRLMLIPSQTLNPDDLIVPREWIDIPELRADYYLSMQVNLDEEEENCWICVRGFVTDVEFENRATYTRSSRLYALSPENWHQDLTLLWETLGIHQAKSVSPLPSISYTTVKDAVRGLSPAALRSPRLRLQLPFAQWGGLMANETWRKELYQQRVKPPALTQWFQTQGSEISTELIAIGWQLYQEVFGGSQLAGTFRRAPVEPKAIASRVKQLELGEEAIALVIDLMEDTEGNLWISPQLRPFNPGDRTQCLPPNLNLALLDDEGTTQVEVRSETATNILQLPQPFCSSPGTEFVLSISLGNQTILEYFTI
>NC_019693.1|WP_015150476.1|5552163_5554281_-|hypothetical-protein
MPILPHVRCRTSLNEKLTTSLEIGFSHNKYQPQWVVKTDAHRSLEQLKKTDDFIQTLYKPEGEPEDWNRFVIYLAQRWQAEQLAGVYPGQPRQRAKGFIKKYELYPLLCAYLDEPAYRAVEKTAKSWKRLKSYTWEHWFSKVQDIINTPHEIIRILENFLHAAQESQGKVSMEFYFKRAFEYKILEKLEQFGISRASDWRLLCMAKESELRQSLKTQGISDLMIERYMFSWDYFKSVYKDNRVNHPGRKKGDRWPNPHQEDYAEVSRYYNQEKELTGVPLAVFQDTPKSSEQIAQWMQESVQALRDSALLDEVNINNPDVLDRLSLQKSVVSPTSSSKSSDLLGNVQEILTENLEQLNSRFAQAIAQGEKPDYIVKLLPLRYGMGLSQQDVGQIFGVHQSQISRRESDYIETLLSLFCQWLADKKGISLERINQDLNQWLSGGYAHPKFSTPIQGFLIETMTKSLSKPERSLLEKHYQKQKTIPQIASEHKLKTGEVEQTLDRAKHPLRRVLCIALWVETSTEKLIRQSYQDSIHSPNLLSDKILEGVATLTEEQQKILRYVYGTQLSQEEVTQKLNCTANELTRQLTASLKELQMILHLKLTELVTTTVKTWLKSHYQTKVLPRFPSRYCEEYQLLTLYYQQRLKPRKIASRLSVGYHVTIEEVVNQLSQAEGLFLEAIQYWCQQQLAISLSEGDLEKVLKKWF
>NC_019693.1|WP_015150477.1|5554384_5554945_-|hypothetical-protein
MGTTLARVEAYLDAWNWNYIVDRANSRIITAVRSEVLNPFQIVIELKEQGRFCRIYVPRLLQFHRHPYRELLLSTLLSLSWETKMLRWEYDSLGGEVRAGIELPLENAELESTQFYRCLSGLIQLIQDALPRLNSVMETGIDPVQCQRGEQLLLMLQEKMPRGFLDELDQAIVAHHSRPNIKQSMV
>NC_019693.1|WP_156823925.1|5555064_5555265_-|hypothetical-protein
MATVHPFRGEMPHRFASVSLLAIAFTLCTAPVRPQLPQPNAHSDYTRVAHDNLPGSHLPVGPLDLF

Crispr_ID: NC_019693_58

• CRISPR_ID: NC_019693_58
• CRISPR_location: 5531086-5531303
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_019693_58

Consensus_repeat	Method
TTATTCGGACTCTCCAATCGGATTCGCTGGTC	CRISPRCasFinder

spacers of NC_019693_58

>58.1|5531118|28|NC_019693|CRISPRCasFinder
CTCCGAACCCGAACTGTTCTGGGATAGT
>58.2|5531178|28|NC_019693|CRISPRCasFinder
CGAAGACCCGGTATTGTTCTGGGATACC
>58.3|5531238|34|NC_019693|CRISPRCasFinder
GGAAGATTCCGAACTCAGTTGGGACTGGACCGAA

CRISPR arrays and Neighbor proteins around NC_019693_58

CRISPR arrays

The CRISPR arrays of NC_019693_58

>merge|NC_019693|58|5531086-5531303|CRISPRCasFinder
TTATTTGGACTCTCCAATCGGATTCGCTGGTCCTCCGAACCCGAACTGTTCTGGGATAGTTTATTTGGACTCAGCAATCGCATTCGTTGGTCCGAAGACCCGGTATTGTTCTGGGATACCCTATTTGGAATGTCCAATCGAGTCCGGTGGATGGAAGATTCCGAACTCAGTTGGGACTGGACCGAATTATTTGGACTCAGCAATCGGATTCGTTGGTC

>NC_019693|58|56|5531086-5531303|CRISPRCasFinder
TTATTTGGACTCTCCAATCGGATTCGCTGGTC	CTCCGAACCCGAACTGTTCTGGGATAGT
TTATTTGGACTCAGCAATCGCATTCGTTGGTC	CGAAGACCCGGTATTGTTCTGGGATACC
CTATTTGGAATGTCCAATCGAGTCCGGTGGAT	GGAAGATTCCGAACTCAGTTGGGACTGGACCGAA
TTATTTGGACTCAGCAATCGGATTCGTTGGTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015150468.1|5526306_5527668_-|putative-calcium-binding-protein	unknown	unknown	gnl|CDD|349398
NC_019693.1|WP_015150470.1|5538576_5539479_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150475.1|5550926_5552138_-|DUF1822-family-protein	unknown	unknown	gnl|CDD|370155
NC_019693.1|WP_015150473.1|5547798_5548524_-|DUF928-domain-containing-protein	unknown	unknown	gnl|CDD|368720
NC_019693.1|WP_015150472.1|5544830_5547686_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|227328
NC_019693.1|WP_015150466.1|5521284_5522193_+|DUF1822-family-protein	unknown	unknown	gnl|CDD|370155
NC_019693.1|WP_015150471.1|5540910_5544879_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|225387
NC_019693.1|WP_015150476.1|5552163_5554281_-|hypothetical-protein	unknown	unknown	gnl|CDD|100119
NC_019693.1|WP_156823925.1|5555064_5555265_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150467.1|5522220_5524044_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NC_019693.1|WP_015150464.1|5518751_5520191_-|hypothetical-protein	unknown	unknown	gnl|CDD|223021
NC_019693.1|WP_015150465.1|5520622_5521261_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823923.1|5525809_5526028_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150477.1|5554384_5554945_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823924.1|5538302_5538494_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823922.1|5511766_5511907_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150462.1|5511997_5517796_+|DUF4114-domain-containing-protein	unknown	unknown	gnl|CDD|238004
NC_019693.1|WP_015150461.1|5511121_5511349_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150474.1|5548523_5550887_-|CHASE2-domain-containing-protein	unknown	unknown	gnl|CDD|226703
NC_019693.1|WP_015150463.1|5517903_5518665_+|hypothetical-protein	unknown	unknown	gnl|CDD|275293

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015150468.1|5526306_5527668_-|putative-calcium-binding-protein	gnl|CDD|349398	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins. Little is known about bacterial and archaeal members of the CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family. The wider family of CAP domain containing proteins includes plant pathogenesis-related protein 1 (PR-1), cysteine-rich secretory proteins (CRISPs), and allergen 5 from vespid venom, among others. Studies of eukaryotic proteins show that CAP domains have several functions, including the binding of cholesterol, lipids and heparan sulfate. This group includes Borrelia burgdorferi outer surface protein BB0689, which does not bind to cholesterol, lipids, or heparan sulfate, and whose function is unknown.	3.93341e-22
NC_019693.1|WP_015150466.1|5521284_5522193_+|DUF1822-family-protein	gnl|CDD|370155	pfam08852, DUF1822, Protein of unknown function (DUF1822). This family of proteins are functionally uncharacterized.	9.73778e-53
NC_019693.1|WP_015150472.1|5544830_5547686_+|CHAT-domain-containing-protein	gnl|CDD|227328	COG4995, COG4995, Uncharacterized protein conserved in bacteria [Function unknown].	1.85514e-78
NC_019693.1|WP_015150473.1|5547798_5548524_-|DUF928-domain-containing-protein	gnl|CDD|368720	pfam06051, DUF928, Domain of Unknown Function (DUF928). Family of uncharacterized bacterial protein.	1.22085e-37
NC_019693.1|WP_015150471.1|5540910_5544879_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl|CDD|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	3.5206e-97
NC_019693.1|WP_015150476.1|5552163_5554281_-|hypothetical-protein	gnl|CDD|100119	cd06171, Sigma70_r4, Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).	0.00100418
NC_019693.1|WP_015150467.1|5522220_5524044_+|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	8.1001e-11
NC_019693.1|WP_015150464.1|5518751_5520191_-|hypothetical-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	2.9935e-17
NC_019693.1|WP_015150475.1|5550926_5552138_-|DUF1822-family-protein	gnl|CDD|370155	pfam08852, DUF1822, Protein of unknown function (DUF1822). This family of proteins are functionally uncharacterized.	2.80417e-45
NC_019693.1|WP_015150463.1|5517903_5518665_+|hypothetical-protein	gnl|CDD|275293	TIGR04500, PpiC_rel_mature, putative peptide maturation system protein. Members of this protein family have a novel N-terminal sequence region. Close homologs to the C-terminal region of this protein score well to PpiC-type peptidyl-prolyl cis-trans isomerase models (see pfam00639), yet no sequence within the family scores well to such models, suggesting origin within a branch of the PpiC family but subsequent neofunctionalization with a rapid change of sequence. The genome context for members always includes an ATP-grasp enzyme associated with peptide modification and a short polypeptide likely to be the modification target.	6.24158e-11
NC_019693.1|WP_015150462.1|5511997_5517796_+|DUF4114-domain-containing-protein	gnl|CDD|238004	cd00044, CysPc, Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.	3.86039e-26
NC_019693.1|WP_015150474.1|5548523_5550887_-|CHASE2-domain-containing-protein	gnl|CDD|226703	COG4252, COG4252, Predicted transmembrane sensor domain [Signal transduction mechanisms].	1.67732e-92

Protein sequences

>NC_019693.1|WP_015150468.1|5526306_5527668_-|putative-calcium-binding-protein
MSTFSPTEAPYLSSLEKGIIDEVNRARTNPSAYAAYLEQIRNSLTTIEGPSVITETIQFLRSQAPLAPVELSQGMTMAARDHVNDKGPQGLMGHQGTDGSTVSDRLNRYGTWQTGAAENISYGKKTARDIVLQLLIDDNVSSRGHRINIFNPQYRFIGIDSGPHGQWGTMSVMKLAGNYTDASSLPTLPAAVPDAQIAFNPSRGTPEIGTPSGVTDFTNLGEFFTLSDASDRINLAEWPDAMGKSVLALNGNDTVIGTTGNDEINGNRGNDDIQGGMGTDYIRGGKDFDVIWGEDGDDILNGNNNDDTVYGGAGDDIVRGGKDNDILFGEAGNDFLVGDFGQDSLIGGPGSDVFVLRSDSQDGLSNTSRFVTEVDIIADFNPNEGDRIGLNNGLSFSSLTFEELDINNGASQQAIALRIGATGDYLGLVLNISSSELQVPDNFVTADQRLMLG
>NC_019693.1|WP_156823923.1|5525809_5526028_-|hypothetical-protein
MNNSIFLNSLFLGLIVMGQPTSTLEVFSTALGSNTGRIGMEISTARNSSEICFDEKGNKYHCASFHESTQFF
>NC_019693.1|WP_015150467.1|5522220_5524044_+|CHAT-domain-containing-protein
MAKLVVIKLEGDFHRQGFGVTLEIGTEGDRPSIELPGKLPPAPDLAIRLQQWEAKYRNLDTLRGLKPKQIFYNGSIVQRVQECRDAAKILSDCFQDWIESKDFLPLDKTLREELNRTEIVRVLIRSNQFLVQKLPWHLWDFFERYPNTELALISPSAKRVDCLKVAQNAVKILAILGHKEGIDIEIDRQILENLPDAAVTFLVEPTPEELSDRLWEDSWDILFFAGHSETQGESGRIYINPQDSLSLEELKYGLTKAVARGLQIAIFNSCDGLGLAREFAELNIPQTVVMREPVPDSVAQRFLQYFLAAFSRGESFYLAMREARERLEGLEGEFPCASWLPVICQNPTMVPPSWADLRGKSREQERVSPLSPLPQIPEKKLHSRPSYSVRFVTGIILASLGIISWQKFAPTLATRLNNSGMDSYGIGDLSDYWKKLDLAWVFDPYNPTVYYNKAWSCEDVLDYDCARVHYQKAARLGSAAAYNQLGSISMKVDEDYHTALHFFTQGLQLATQDRDKFALYKNLGWTQLKLGREVEAGDSLEMALNLHQNYASPYCLLAQVRENLGQVPEAIALWEECQTLANLQKPEEYLWLGMAKQRLSEIRPPQN
>NC_019693.1|WP_015150466.1|5521284_5522193_+|DUF1822-family-protein
MEMNIEQLTFTTSLIQKYHQMAQQFGQQHLTKAKSAQVYQNTLAVLSVNYYCQCLGIPTQLTASDSWNPILQSLLDIADLQLAKGGKIECLPVQVDADWVEVPPEVLTDRIGYIAVEINPSQTQARLLGFTETISSNPVPLSQLQGLESFIDRLHAIPSTQRIHLSQWLHHCWDAGWKRVEDLLEVPQLELALQFRTTQTAVKGGKLLDLNSTGDSVALLVGIKPTNPPEMDIWVEVYPIGEQTHLPRDLQVMVLDSSQVSVMQAQARSTKNIQLNFSGEPGDQFSIKLELGDVSVTEAFII
>NC_019693.1|WP_015150465.1|5520622_5521261_+|hypothetical-protein
MPERDRNRQNEEMQHYAELAQGHPPQSRERQLALTKLVGAIAGSGKLSRPRQGEFIAVYEEIYAEALSLLWLFVCENIDRYDSGRGSVMTWVNYLLDKRFIIEGIKTIVGKKGDRPLSTVEVELIPQPETLPSPSQFLEQYIEEDREGLFQSTHLKYRPDVNFQQIALARLAGVKWKTLSVDLNVTVSTLSSFYQRSLKELSAPLQMLFIDE
>NC_019693.1|WP_015150464.1|5518751_5520191_-|hypothetical-protein
MEINVFDPTFYRSIHPDLSEFNDSETFDHLINHGLNEGRKFSPFLDLNVYGSINPDLATAGLTSNQQLYEHWQLFGVNEGRSFSRVFQADFYQQNAPDLQAAGLSNAELFNHFRTLGIEEGRQASPLFNVNFYLASNPDLQAAGFNNRQALDHYIVHGIPEGRMGFQVPPMIPNQPPTSPQPPPLPPGPDNPAPGATPGPFLPFPATGPEATGPQQPTPGVGPATPPTPPISLQPPGMPPFPDNPAPGATPGSPPPIPPQGPEATGPQQPTPGVGPAAPPPPPISPPPPVATPPGIPAPDATAGPPLPIPPQGPGATEPQQPTPGVGPVAPPPPPISPPPPGLTTPERPTPVAGPGPGIPIPPPPPGSTTPQRPTPVAGPAPGIPIPTPSTDNEEQEEDEITRTSQASQNYQLTPEAIHSGELRSFTAQTSWTDIFANGVASPSADMVLRETFVSPVGDNVGQMNFLSAPNYGADFLLM
>NC_019693.1|WP_015150463.1|5517903_5518665_+|hypothetical-protein
MKVSQTVDLMKIGTDTISLQEALSYLKQSGQFGQFVSTVLREYIIEREIQILEFCPSQTEIEQFLLDFRIQNRIIESQAFEQWLFQNQLTYEQFRERSLKGLNFQKLREQVVQGKVEAFFAENSRLFDRLVLSRLVVEGPNLSHKIGEMLNQDPQQFKALVGEYSIAEDRVLDGRMGVFPWQELPPQLKSELDGKSPGDIVGPIVVDGLFCFFKIDQILEAKLNDTICQEIENRLFEEWLRGKMQGNNIQMLV
>NC_019693.1|WP_015150462.1|5511997_5517796_+|DUF4114-domain-containing-protein
MFNLFFGLQKRPQANGFQSPSKRYQGPAMRLEEMRTPTGLVLDDTETTDYSGFVTDSDLDFEFPSEESDIGEELPGEELDPESLDFAENSSTETNSAEEDFEDLPYFDITESTDAEPEESSSDETAQFVSDSADSSNSTNPKLEELDWIESDGSSHENIGDESELNPDQELLPESSEEAVEEAVLTTPTEEIDPEVEEPDIVSQLPETDTEETSISDEIETLTPQSDPIGTDEIEAEDSSFFAELEEVEESELDSSIYEPSDSVVTETDEGIASEADSSIGDSESEPFVNEETETNSNADELEDSAILETEETIDDSETEENDLVANAELSNLKPQFESGTFRVGETGEVEVDFLFDGGAYKGEVAIVSLSGMEGLDPTSQEFFLESISRAASNSELGYIIINDSIEGARFSGDLGEADYNSGEYQGVKSFAMRPGDEFFLMLVPNGTLQQVLDNPNAGGAVRPLFSLATANPEDGYHFGQIADIIGDGSAFAWEDIRIDGGSDRDYNDIVLQFRGATGKAALMDDVVAAGKDWRGTELGQELINYVNSQQPEEPIAETPEEPVAETPEEPQEPQEPVAETPEEPQEPVAETPEEPQEPEEPVAETPEEPQEPEEPVAETPEEPQEPVAETPEEPEEPVAETPEEPQEPVAETPEEPQEPEAETPEEPQEPEAETPEEPQEPEEPVSMERPFTEQEIVKDDWERSTAYAEGETEPDPDVPDTVDPATVINLGNLNRDAFLENQLNSQEDGLGETGVTSTNFSESSVEALPQDGFGNVSNQAPVVTTYNQTLNPGTSIAGTDLFTVYDPDGDAIQWYWLYDYNSNMANSSTSGYFTLNGIKQNNGFSINESQLATVEFVAGSESGTDKIYIQAYDGTTWSESSLVMVTTELPNQAPVVSLNSHPYFAKPSVDTALDFFTVTDPDGDPITLYAFSTSSVYGRNGYLTVDGVAQDHSWFTVEADQLDQVNFVSTTNAGYARILVKAYDGQAWSDPVQTTVNIMRSVTADDFTLEVGSSISVQDFLVEDTDTPFITRYWFEDTNKSSTSGYFTVNGIKQNGTYFTVDADQLDTVHFVAGAESGDDGVRIRPMTERGSWSGHFTNLTITTEPANQVPEVTTYNQTLNPGTSLAASEFFTVYDADGDEIEMYYFYDINGNSTSGYFTLNGVEQTGAFTVTASQLGMVQFVAGSQAATDSVYIYAYDGKIWSGYSNVILTTEVVNHAPVVTTYNQTLNPGTSLSASDFFSVYDADGDAIEWYYFYDTNSNSTSGYFTLNGVEQTSGFAVTASQLGMVQFVAGSQAATDPLYVYAHDGKTWSEYSTLTLTTEVLNRAPEVTTYNQTVNRSESIIPYFTVTDADGDTITRYALYDGNTHANSGYFTIDGVKQEAGQIIYVDANQLSQVEFIGGASATTEQLYIAASDGKAWSSWSNYTVQTQPGSTPTVVINNATVDVNTSTSLTLNVSDLDGDTVTRYEFFDSNAQSTSGYFTVNGVQQEAGKSFFVDADQLHTVQFIGGAAAGSDRIAIRATDGIDGWGNWSYAEFTTEETVTYDWFDLNIKDTTIRALARSNFQDGILCRHDMIDIFDSAKNNGFVSTDQLADLQLLSSDVTYIQMADHARILSQKIAHGDITNQQYLGQSLGNLYEESSATHLQKLIDKHFFGKDLPGLTGDYAYGKANDATYKFVQGELFQDGIDYTDVRQGYLGDCYYLAALAGIAMQDSQKIEEMFIDNGDGTYTVRFFNNGTADYVTVNRLLPTLDSGQFIFASVGGTLQQSWWSANPYYVQNTYNNVNNELWVALAEKAYAQINEAAWIGQDGTNSYKGIEEGRAQVASEHIAEVEGKYHDFSHSSVAAAIAAFTAGSAVFFSSDKNQHGTLIGSDKLVGGHAYLLTSYDSVNKTVTLFNPWNSGNSYDKDGYLTVSWNEVSTYFYAWREAS
>NC_019693.1|WP_156823922.1|5511766_5511907_-|hypothetical-protein
MNSAIARCIRTNAIAPESPSFVSYLFIREAEAKLCTDHASPEENFT
>NC_019693.1|WP_015150461.1|5511121_5511349_-|hypothetical-protein
MTLLIALFIVGWVAVAVLGTQAYFRGEQSKPIHERNWRSDSFETLAESITGTDIDYSKRVPAFEVDAYTSSNLPS
>NC_019693.1|WP_156823924.1|5538302_5538494_+|hypothetical-protein
MDSNSFLTIAIGPVDLDGRSCWCWVRDRLPASIDDPIIQRELREVLFQEWLQKQLKETTLRLD
>NC_019693.1|WP_015150470.1|5538576_5539479_+|hypothetical-protein
MTRFIHDQFAKQYLEELLSPFGTVETGKTIAAEVQEVDVLFIANPESNRDRSSLGLLGQIAGNQSIFEPFRNAVQPKQIRSCLAKLYAIQSNEERKANRDNTPLPEEEVITGWILTPTASSSLLDYFGATEDPIIGVKGVYSLARGLKMGLIAIHQLPVNPETLSLRLLGKGRVQQQAVNEIQGLPDDNPWKLAALELLYNLRTILEVRQDLEPDDQELIMELSPLYLQRLEDATQRGRQEGNQQGQRLMIESMLQVKFGEVDAELAQIIDPLIELTPLERTQLIMQLSRDEILTRFLNN
>NC_019693.1|WP_015150471.1|5540910_5544879_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MTLFMKPLLFPVALAGSLTLCWFAIVPTRTSAQIVPDRTLPENSRVTPDDNTFIIEGGTSTTGGTLFHSFEEFSVPTNTEALFNNTDQINQILTRITGASISNIDGILRANGNANLFFLNPNGIVFGPNARLELGGSFLATTGDRFVFADGSFFSASNPETLPLLTVNAPIGLQFGTTSGPINVLGIGHNLVPDELGAVDRSNRSDGLQVNPGNTLAILGSSVTLDGGNLIAESGRIEVGSVSAGSEIKLNSQEQGLIFDYQNVRGFQDVQLTEKASIDASGPGGGDIRVHGRNINLNDFSVVLSLTEGNESGQTLQVNASDSIKLNELSAILAETYGTGIGSTLNINTGLLLIENGSTISAGVNDGEPGNVLSINVRELILENGGQISASSFFENGKAGDIHIRASDSITASGEGEDISEEMRASGIFANQNDPLGTRPGGNITLETRNLTVDSGAQIAVGTIGFGQAGTLRVTALDSIELAGRAQDPEFSSGLFASTLGFGNAGNLIIETSRLIVRDGAVISVKGQTLNDLEMVWGIEDIDNLPEEALDFFGIENPTELALGQAGNLTINSPLILLNEQGIIRATTVAGDNANIQITTNNLQLRRGSNITTDASRLATGGNITIDTQTLVLGENSNITARATDGRGGNIQVNTTADIRSFDSAIDASSQRGIDGVVAINRPEVDPAAALVELEEDRINPVALVPRGCDVGSSDNSSRFIVSGWGGLPPSPREPRSGGNFIDNLDPLPARNYEGSGENLGNFSLGEAVPVQRISEASNWQLNEQGEVVLIAAVEKSSPDLPGIGCDGEALSPGLKNVETAASGIPESITVDRFNVVGNSVFSEAEVSQVLSPYTNRSLSFADLREARSAITNLYVEAGYITTGAYLPPQTVRENTVEIAVVPGMLREIQVNSNRLHNYVHDRLMVAIGNEPVNVNRIVEALRLLRLDPLIQEVQGELRAVPIPGQNILEVNIIEASPFSGTQLVLDNRRSPGVSTFRQQVQGNYNNLLGLGDRLFFSYARTEGSNTWEGSYIVPITPRNTTLGFRYSNGNSQIVESPFDRLDIEANSRLYELTLRQPFQRATPEYTREFALGLTASRQASETSLLGDRFPLSAGANNNGELRVSALRFFQDWTQRQPEQVLALRSTFSLGVDAFDATVNNNAPDSRFFAWRGQGQWVRSFGRDTLLFVRGDVQLSPDNLVSFEQIGLGGLDTVRGYRQDTLLTDNGVLGSVELRLPVFRFAGGNGLVQIAPFLDVGTGWNSAGQANPNTTSLVSLGLGLQLELGNQLTARLDFGKPLVDINSRNRTWQENGIHFSVKYNPF
>NC_019693.1|WP_015150472.1|5544830_5547686_+|CHAT-domain-containing-protein
MARKWHPFFGKVQSFLNRGWKFILISIFATITILNLQGGSPVLAYQPWGETVAQTPSFDGEMRLEEGSRFYENLRFAEAETAWRASVGLLSGEEKALGLSYLALAQLRQSKLDEADISIQESLRLLNQVTTPGTSERNQIIHARILTTAAQVNLARNQPELAAHALEQFAEATTIYEKLNQQEWVIASQINQAQAMQQLGMYREALKTLKNLENLILHHSDSEIPLSGLLSLGKTYRAIGVLDQSYCVLEAGKENPEIALELGNTAQAIGKRIKDQLDSVNEKTSEPIFTTEQGVENCTIPFKDIPLISAWDFYEKAQDFYQQSWNSPAVKPETQVQGMLNTLSLALDLKDAKELEEETKSNLERQAHELPPQVLQLIEILPSLNREKVYDRIHLARSLTRLNLEELSQNQLETAIAEAQELADQRAQAYAIGELGWMKQQQGNWTEAEQWTRQAMAITPPDAIDIRYQWEWQLGQILKEEGRTEEAIRHYTEAVDLLQRVRQNLVAIAAGMGEMNADLQFDFRDRVEPVYRELVGLLLDSQGNEVTSQDHIQTALGVIELLQVAELENFLQCDLQPEPQVQLARSVAEAKQKVAEKLNAIHQKKPDYAVIYPIIIQDKLEVILGLPGTPLVHYSNPSSDNIKKILADFRRQLIIPRDFEAVKNQSFQLYKMLINPFKSKIDNKSLLFILDVPLQSVPMGALYNKITEKYLIQTHTIRMTSSLQLLQIDAEKHPITEVLTAGIAQPRTERNIPFSSLDHVEQELDDIRKHFPGSQKLFEEKFTQSNLEQALSHQTFPAIHLATHGHFSSQRYLTFLLDGQTIIEVADFKRLFAEPSYLTTNPIQLLVLSACQTAQGDRKSALGIAGLTVSGQINNTIASLWSVKDQSTARLMNKFYEKLMEFSSPDLSQSDRTALALQEAQKSMIEEQESILRRRHHPSSWSPFILLSNAL
>NC_019693.1|WP_015150473.1|5547798_5548524_-|DUF928-domain-containing-protein
MKTSSSGNRFGFMFLSLFMIMINLPIQVLSNENNQNSPFRGRGRPSNVIGGGSRGNCEVTAEHQTLRLTALVPAEIGGVTQRERPTWWFYSPFNQRVYSPLQAQFIVTKDDKNFLPPIDVTLPEIPGFFPVSIPPDSPLEVNKWYMWTLLVICDPQDESKHIDINGWIKRIPEHEDSEEYLRWYDPLDSIAQTQCDNPDDREALQQWEERLSSVEDQLEPWDQKVWKEVRDQRMVCHRDLN
>NC_019693.1|WP_015150474.1|5548523_5550887_-|CHASE2-domain-containing-protein
MAKLVKLSLEGDLTSGYEVELIQISEEERDGKVLIEGIGGQLPAAAEIYECYQTWQQNYEQLDRIYRGGEFRFLGVETSSNVSLAKCQQLSQILEQKINDWLDAPGFRAIADRILTYLNPEEDIRFLIKTSDYNLWQIPWSAWIFFETHPNAEVVFSSFDAKYGEKPIKATPRKNVRILSVFGSDENINTKPDQEQIERLKSVGAEPTLIIKPRADHLRNLLWDKSWDILFFAGHGDRDKDSQKGKIYLNSNEYLTPSEFKNTLKTAIVDRNLKIVFLNSCLGLEFAYELVVDFKIPVVIAMREQIPDDAAQNFLQYFLLEYADNKRPLYVAVRRAKERIAEEFQDKYPGLNWLPVVCQNPAHIPLKWGDLYNKVSVKQAAVTSLFCTLMVVLARSLGFLQPLEFMTYDWLMSLRPLESVDERIVIITIDEQDIQYQINEGFKPSLASSFSHEALDRLLQKISPYQPRVVGLDIFYNIPFEGKSLQNQIESLNQLIGICQLGDETNPNNPPIPPPPGLTTIGFVDMPVDSDGVIRRQLYGAWPPEDCPTDFSFNLRVANSYLEQELNQTNLITVTQSDNMSINQVIFPILNRRYGGYQIKGDDLSGYQGLLNYRNARFHQRSLRGILQGESDQELDELIRDRIVLIGVTRPPRSDKHPTPLINDWRDNLYGVEIQAQKISHIISAVLDGRTLFWWWGEKTENLWIASWSLMGGVLVWKLRSPLKIGLGSIIAIGILGGICFLLLLEGGWIPLFPSACGFLLTVSVLNVNPKFYQFPQKYTLKIAQAI
>NC_019693.1|WP_015150475.1|5550926_5552138_-|DUF1822-family-protein
MNANVTHPFPPIAPDELYFNLSFEMQAQAWQKSRCHSNPIARNQAYLGHLCLQGFMSWVLERFEGNSQFVEPYVNHLESLWEFIEGVPIIVGKNRLMLIPSQTLNPDDLIVPREWIDIPELRADYYLSMQVNLDEEEENCWICVRGFVTDVEFENRATYTRSSRLYALSPENWHQDLTLLWETLGIHQAKSVSPLPSISYTTVKDAVRGLSPAALRSPRLRLQLPFAQWGGLMANETWRKELYQQRVKPPALTQWFQTQGSEISTELIAIGWQLYQEVFGGSQLAGTFRRAPVEPKAIASRVKQLELGEEAIALVIDLMEDTEGNLWISPQLRPFNPGDRTQCLPPNLNLALLDDEGTTQVEVRSETATNILQLPQPFCSSPGTEFVLSISLGNQTILEYFTI
>NC_019693.1|WP_015150476.1|5552163_5554281_-|hypothetical-protein
MPILPHVRCRTSLNEKLTTSLEIGFSHNKYQPQWVVKTDAHRSLEQLKKTDDFIQTLYKPEGEPEDWNRFVIYLAQRWQAEQLAGVYPGQPRQRAKGFIKKYELYPLLCAYLDEPAYRAVEKTAKSWKRLKSYTWEHWFSKVQDIINTPHEIIRILENFLHAAQESQGKVSMEFYFKRAFEYKILEKLEQFGISRASDWRLLCMAKESELRQSLKTQGISDLMIERYMFSWDYFKSVYKDNRVNHPGRKKGDRWPNPHQEDYAEVSRYYNQEKELTGVPLAVFQDTPKSSEQIAQWMQESVQALRDSALLDEVNINNPDVLDRLSLQKSVVSPTSSSKSSDLLGNVQEILTENLEQLNSRFAQAIAQGEKPDYIVKLLPLRYGMGLSQQDVGQIFGVHQSQISRRESDYIETLLSLFCQWLADKKGISLERINQDLNQWLSGGYAHPKFSTPIQGFLIETMTKSLSKPERSLLEKHYQKQKTIPQIASEHKLKTGEVEQTLDRAKHPLRRVLCIALWVETSTEKLIRQSYQDSIHSPNLLSDKILEGVATLTEEQQKILRYVYGTQLSQEEVTQKLNCTANELTRQLTASLKELQMILHLKLTELVTTTVKTWLKSHYQTKVLPRFPSRYCEEYQLLTLYYQQRLKPRKIASRLSVGYHVTIEEVVNQLSQAEGLFLEAIQYWCQQQLAISLSEGDLEKVLKKWF
>NC_019693.1|WP_015150477.1|5554384_5554945_-|hypothetical-protein
MGTTLARVEAYLDAWNWNYIVDRANSRIITAVRSEVLNPFQIVIELKEQGRFCRIYVPRLLQFHRHPYRELLLSTLLSLSWETKMLRWEYDSLGGEVRAGIELPLENAELESTQFYRCLSGLIQLIQDALPRLNSVMETGIDPVQCQRGEQLLLMLQEKMPRGFLDELDQAIVAHHSRPNIKQSMV
>NC_019693.1|WP_156823925.1|5555064_5555265_-|hypothetical-protein
MATVHPFRGEMPHRFASVSLLAIAFTLCTAPVRPQLPQPNAHSDYTRVAHDNLPGSHLPVGPLDLF

Crispr_ID: NC_019693_56

• CRISPR_ID: NC_019693_56
• CRISPR_location: 5530351-5530620
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NC_019693_56

Consensus_repeat	Method
TTATTCGGACTCTCCAATCGGATTCGCTGGTC	CRISPRCasFinder

spacers of NC_019693_56

>56.1|5530383|25|NC_019693|CRISPRCasFinder
GGATGAGGAGATGTCCTGGAATGAG
>56.2|5530440|28|NC_019693|CRISPRCasFinder
CGATGAGGAAGAACTGTCCTGGAATAAA
>56.3|5530500|28|NC_019693|CRISPRCasFinder
TGAGGACCCGCAACAGTTTTTAGAAGGA
>56.4|5530560|28|NC_019693|CRISPRCasFinder
GGATGATAGCGAGATGAATTTAGAGGAC

CRISPR arrays and Neighbor proteins around NC_019693_56

CRISPR arrays

The CRISPR arrays of NC_019693_56

>merge|NC_019693|56|5530351-5530620|CRISPRCasFinder
TTATTTGGACTTTCTAACCGTCTGCGGTGGATGGATGAGGAGATGTCCTGGAATGAGTTATTTGGACTCTCTAATCGGATTCGCTGGTCCGATGAGGAAGAACTGTCCTGGAATAAATTATTTGGCCTTTCTAATCGGATTCGGTGGTCTGAGGACCCGCAACAGTTTTTAGAAGGATTATTTGGACTCTCCAATCGGATTCGCTGGGCGGATGATAGCGAGATGAATTTAGAGGACTTGTTTGGACTTTCCAATCGGTTGCGGTGGGCG

>NC_019693|56|54|5530351-5530620|CRISPRCasFinder
TTATTTGGACTTTCTAACCGTCTGCGGTGGAT	GGATGAGGAGATGTCCTGGAATGAG
TTATTTGGACTCTCTAATCGGATTCGCTGGTC	CGATGAGGAAGAACTGTCCTGGAATAAA
TTATTTGGCCTTTCTAATCGGATTCGGTGGTC	TGAGGACCCGCAACAGTTTTTAGAAGGA
TTATTTGGACTCTCCAATCGGATTCGCTGGGC	GGATGATAGCGAGATGAATTTAGAGGAC
TTGTTTGGACTTTCCAATCGGTTGCGGTGGGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015150468.1|5526306_5527668_-|putative-calcium-binding-protein	unknown	unknown	gnl|CDD|349398
NC_019693.1|WP_015150470.1|5538576_5539479_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150475.1|5550926_5552138_-|DUF1822-family-protein	unknown	unknown	gnl|CDD|370155
NC_019693.1|WP_015150473.1|5547798_5548524_-|DUF928-domain-containing-protein	unknown	unknown	gnl|CDD|368720
NC_019693.1|WP_015150472.1|5544830_5547686_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|227328
NC_019693.1|WP_015150466.1|5521284_5522193_+|DUF1822-family-protein	unknown	unknown	gnl|CDD|370155
NC_019693.1|WP_015150471.1|5540910_5544879_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|225387
NC_019693.1|WP_015150476.1|5552163_5554281_-|hypothetical-protein	unknown	unknown	gnl|CDD|100119
NC_019693.1|WP_156823925.1|5555064_5555265_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150467.1|5522220_5524044_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NC_019693.1|WP_015150464.1|5518751_5520191_-|hypothetical-protein	unknown	unknown	gnl|CDD|223021
NC_019693.1|WP_015150465.1|5520622_5521261_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823923.1|5525809_5526028_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150477.1|5554384_5554945_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823924.1|5538302_5538494_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823922.1|5511766_5511907_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150462.1|5511997_5517796_+|DUF4114-domain-containing-protein	unknown	unknown	gnl|CDD|238004
NC_019693.1|WP_015150461.1|5511121_5511349_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150474.1|5548523_5550887_-|CHASE2-domain-containing-protein	unknown	unknown	gnl|CDD|226703
NC_019693.1|WP_015150463.1|5517903_5518665_+|hypothetical-protein	unknown	unknown	gnl|CDD|275293

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015150468.1|5526306_5527668_-|putative-calcium-binding-protein	gnl|CDD|349398	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins. Little is known about bacterial and archaeal members of the CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family. The wider family of CAP domain containing proteins includes plant pathogenesis-related protein 1 (PR-1), cysteine-rich secretory proteins (CRISPs), and allergen 5 from vespid venom, among others. Studies of eukaryotic proteins show that CAP domains have several functions, including the binding of cholesterol, lipids and heparan sulfate. This group includes Borrelia burgdorferi outer surface protein BB0689, which does not bind to cholesterol, lipids, or heparan sulfate, and whose function is unknown.	3.93341e-22
NC_019693.1|WP_015150466.1|5521284_5522193_+|DUF1822-family-protein	gnl|CDD|370155	pfam08852, DUF1822, Protein of unknown function (DUF1822). This family of proteins are functionally uncharacterized.	9.73778e-53
NC_019693.1|WP_015150472.1|5544830_5547686_+|CHAT-domain-containing-protein	gnl|CDD|227328	COG4995, COG4995, Uncharacterized protein conserved in bacteria [Function unknown].	1.85514e-78
NC_019693.1|WP_015150473.1|5547798_5548524_-|DUF928-domain-containing-protein	gnl|CDD|368720	pfam06051, DUF928, Domain of Unknown Function (DUF928). Family of uncharacterized bacterial protein.	1.22085e-37
NC_019693.1|WP_015150471.1|5540910_5544879_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl|CDD|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	3.5206e-97
NC_019693.1|WP_015150476.1|5552163_5554281_-|hypothetical-protein	gnl|CDD|100119	cd06171, Sigma70_r4, Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).	0.00100418
NC_019693.1|WP_015150467.1|5522220_5524044_+|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	8.1001e-11
NC_019693.1|WP_015150464.1|5518751_5520191_-|hypothetical-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	2.9935e-17
NC_019693.1|WP_015150475.1|5550926_5552138_-|DUF1822-family-protein	gnl|CDD|370155	pfam08852, DUF1822, Protein of unknown function (DUF1822). This family of proteins are functionally uncharacterized.	2.80417e-45
NC_019693.1|WP_015150463.1|5517903_5518665_+|hypothetical-protein	gnl|CDD|275293	TIGR04500, PpiC_rel_mature, putative peptide maturation system protein. Members of this protein family have a novel N-terminal sequence region. Close homologs to the C-terminal region of this protein score well to PpiC-type peptidyl-prolyl cis-trans isomerase models (see pfam00639), yet no sequence within the family scores well to such models, suggesting origin within a branch of the PpiC family but subsequent neofunctionalization with a rapid change of sequence. The genome context for members always includes an ATP-grasp enzyme associated with peptide modification and a short polypeptide likely to be the modification target.	6.24158e-11
NC_019693.1|WP_015150462.1|5511997_5517796_+|DUF4114-domain-containing-protein	gnl|CDD|238004	cd00044, CysPc, Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.	3.86039e-26
NC_019693.1|WP_015150474.1|5548523_5550887_-|CHASE2-domain-containing-protein	gnl|CDD|226703	COG4252, COG4252, Predicted transmembrane sensor domain [Signal transduction mechanisms].	1.67732e-92

Protein sequences

>NC_019693.1|WP_015150468.1|5526306_5527668_-|putative-calcium-binding-protein
MSTFSPTEAPYLSSLEKGIIDEVNRARTNPSAYAAYLEQIRNSLTTIEGPSVITETIQFLRSQAPLAPVELSQGMTMAARDHVNDKGPQGLMGHQGTDGSTVSDRLNRYGTWQTGAAENISYGKKTARDIVLQLLIDDNVSSRGHRINIFNPQYRFIGIDSGPHGQWGTMSVMKLAGNYTDASSLPTLPAAVPDAQIAFNPSRGTPEIGTPSGVTDFTNLGEFFTLSDASDRINLAEWPDAMGKSVLALNGNDTVIGTTGNDEINGNRGNDDIQGGMGTDYIRGGKDFDVIWGEDGDDILNGNNNDDTVYGGAGDDIVRGGKDNDILFGEAGNDFLVGDFGQDSLIGGPGSDVFVLRSDSQDGLSNTSRFVTEVDIIADFNPNEGDRIGLNNGLSFSSLTFEELDINNGASQQAIALRIGATGDYLGLVLNISSSELQVPDNFVTADQRLMLG
>NC_019693.1|WP_156823923.1|5525809_5526028_-|hypothetical-protein
MNNSIFLNSLFLGLIVMGQPTSTLEVFSTALGSNTGRIGMEISTARNSSEICFDEKGNKYHCASFHESTQFF
>NC_019693.1|WP_015150467.1|5522220_5524044_+|CHAT-domain-containing-protein
MAKLVVIKLEGDFHRQGFGVTLEIGTEGDRPSIELPGKLPPAPDLAIRLQQWEAKYRNLDTLRGLKPKQIFYNGSIVQRVQECRDAAKILSDCFQDWIESKDFLPLDKTLREELNRTEIVRVLIRSNQFLVQKLPWHLWDFFERYPNTELALISPSAKRVDCLKVAQNAVKILAILGHKEGIDIEIDRQILENLPDAAVTFLVEPTPEELSDRLWEDSWDILFFAGHSETQGESGRIYINPQDSLSLEELKYGLTKAVARGLQIAIFNSCDGLGLAREFAELNIPQTVVMREPVPDSVAQRFLQYFLAAFSRGESFYLAMREARERLEGLEGEFPCASWLPVICQNPTMVPPSWADLRGKSREQERVSPLSPLPQIPEKKLHSRPSYSVRFVTGIILASLGIISWQKFAPTLATRLNNSGMDSYGIGDLSDYWKKLDLAWVFDPYNPTVYYNKAWSCEDVLDYDCARVHYQKAARLGSAAAYNQLGSISMKVDEDYHTALHFFTQGLQLATQDRDKFALYKNLGWTQLKLGREVEAGDSLEMALNLHQNYASPYCLLAQVRENLGQVPEAIALWEECQTLANLQKPEEYLWLGMAKQRLSEIRPPQN
>NC_019693.1|WP_015150466.1|5521284_5522193_+|DUF1822-family-protein
MEMNIEQLTFTTSLIQKYHQMAQQFGQQHLTKAKSAQVYQNTLAVLSVNYYCQCLGIPTQLTASDSWNPILQSLLDIADLQLAKGGKIECLPVQVDADWVEVPPEVLTDRIGYIAVEINPSQTQARLLGFTETISSNPVPLSQLQGLESFIDRLHAIPSTQRIHLSQWLHHCWDAGWKRVEDLLEVPQLELALQFRTTQTAVKGGKLLDLNSTGDSVALLVGIKPTNPPEMDIWVEVYPIGEQTHLPRDLQVMVLDSSQVSVMQAQARSTKNIQLNFSGEPGDQFSIKLELGDVSVTEAFII
>NC_019693.1|WP_015150465.1|5520622_5521261_+|hypothetical-protein
MPERDRNRQNEEMQHYAELAQGHPPQSRERQLALTKLVGAIAGSGKLSRPRQGEFIAVYEEIYAEALSLLWLFVCENIDRYDSGRGSVMTWVNYLLDKRFIIEGIKTIVGKKGDRPLSTVEVELIPQPETLPSPSQFLEQYIEEDREGLFQSTHLKYRPDVNFQQIALARLAGVKWKTLSVDLNVTVSTLSSFYQRSLKELSAPLQMLFIDE
>NC_019693.1|WP_015150464.1|5518751_5520191_-|hypothetical-protein
MEINVFDPTFYRSIHPDLSEFNDSETFDHLINHGLNEGRKFSPFLDLNVYGSINPDLATAGLTSNQQLYEHWQLFGVNEGRSFSRVFQADFYQQNAPDLQAAGLSNAELFNHFRTLGIEEGRQASPLFNVNFYLASNPDLQAAGFNNRQALDHYIVHGIPEGRMGFQVPPMIPNQPPTSPQPPPLPPGPDNPAPGATPGPFLPFPATGPEATGPQQPTPGVGPATPPTPPISLQPPGMPPFPDNPAPGATPGSPPPIPPQGPEATGPQQPTPGVGPAAPPPPPISPPPPVATPPGIPAPDATAGPPLPIPPQGPGATEPQQPTPGVGPVAPPPPPISPPPPGLTTPERPTPVAGPGPGIPIPPPPPGSTTPQRPTPVAGPAPGIPIPTPSTDNEEQEEDEITRTSQASQNYQLTPEAIHSGELRSFTAQTSWTDIFANGVASPSADMVLRETFVSPVGDNVGQMNFLSAPNYGADFLLM
>NC_019693.1|WP_015150463.1|5517903_5518665_+|hypothetical-protein
MKVSQTVDLMKIGTDTISLQEALSYLKQSGQFGQFVSTVLREYIIEREIQILEFCPSQTEIEQFLLDFRIQNRIIESQAFEQWLFQNQLTYEQFRERSLKGLNFQKLREQVVQGKVEAFFAENSRLFDRLVLSRLVVEGPNLSHKIGEMLNQDPQQFKALVGEYSIAEDRVLDGRMGVFPWQELPPQLKSELDGKSPGDIVGPIVVDGLFCFFKIDQILEAKLNDTICQEIENRLFEEWLRGKMQGNNIQMLV
>NC_019693.1|WP_015150462.1|5511997_5517796_+|DUF4114-domain-containing-protein
MFNLFFGLQKRPQANGFQSPSKRYQGPAMRLEEMRTPTGLVLDDTETTDYSGFVTDSDLDFEFPSEESDIGEELPGEELDPESLDFAENSSTETNSAEEDFEDLPYFDITESTDAEPEESSSDETAQFVSDSADSSNSTNPKLEELDWIESDGSSHENIGDESELNPDQELLPESSEEAVEEAVLTTPTEEIDPEVEEPDIVSQLPETDTEETSISDEIETLTPQSDPIGTDEIEAEDSSFFAELEEVEESELDSSIYEPSDSVVTETDEGIASEADSSIGDSESEPFVNEETETNSNADELEDSAILETEETIDDSETEENDLVANAELSNLKPQFESGTFRVGETGEVEVDFLFDGGAYKGEVAIVSLSGMEGLDPTSQEFFLESISRAASNSELGYIIINDSIEGARFSGDLGEADYNSGEYQGVKSFAMRPGDEFFLMLVPNGTLQQVLDNPNAGGAVRPLFSLATANPEDGYHFGQIADIIGDGSAFAWEDIRIDGGSDRDYNDIVLQFRGATGKAALMDDVVAAGKDWRGTELGQELINYVNSQQPEEPIAETPEEPVAETPEEPQEPQEPVAETPEEPQEPVAETPEEPQEPEEPVAETPEEPQEPEEPVAETPEEPQEPVAETPEEPEEPVAETPEEPQEPVAETPEEPQEPEAETPEEPQEPEAETPEEPQEPEEPVSMERPFTEQEIVKDDWERSTAYAEGETEPDPDVPDTVDPATVINLGNLNRDAFLENQLNSQEDGLGETGVTSTNFSESSVEALPQDGFGNVSNQAPVVTTYNQTLNPGTSIAGTDLFTVYDPDGDAIQWYWLYDYNSNMANSSTSGYFTLNGIKQNNGFSINESQLATVEFVAGSESGTDKIYIQAYDGTTWSESSLVMVTTELPNQAPVVSLNSHPYFAKPSVDTALDFFTVTDPDGDPITLYAFSTSSVYGRNGYLTVDGVAQDHSWFTVEADQLDQVNFVSTTNAGYARILVKAYDGQAWSDPVQTTVNIMRSVTADDFTLEVGSSISVQDFLVEDTDTPFITRYWFEDTNKSSTSGYFTVNGIKQNGTYFTVDADQLDTVHFVAGAESGDDGVRIRPMTERGSWSGHFTNLTITTEPANQVPEVTTYNQTLNPGTSLAASEFFTVYDADGDEIEMYYFYDINGNSTSGYFTLNGVEQTGAFTVTASQLGMVQFVAGSQAATDSVYIYAYDGKIWSGYSNVILTTEVVNHAPVVTTYNQTLNPGTSLSASDFFSVYDADGDAIEWYYFYDTNSNSTSGYFTLNGVEQTSGFAVTASQLGMVQFVAGSQAATDPLYVYAHDGKTWSEYSTLTLTTEVLNRAPEVTTYNQTVNRSESIIPYFTVTDADGDTITRYALYDGNTHANSGYFTIDGVKQEAGQIIYVDANQLSQVEFIGGASATTEQLYIAASDGKAWSSWSNYTVQTQPGSTPTVVINNATVDVNTSTSLTLNVSDLDGDTVTRYEFFDSNAQSTSGYFTVNGVQQEAGKSFFVDADQLHTVQFIGGAAAGSDRIAIRATDGIDGWGNWSYAEFTTEETVTYDWFDLNIKDTTIRALARSNFQDGILCRHDMIDIFDSAKNNGFVSTDQLADLQLLSSDVTYIQMADHARILSQKIAHGDITNQQYLGQSLGNLYEESSATHLQKLIDKHFFGKDLPGLTGDYAYGKANDATYKFVQGELFQDGIDYTDVRQGYLGDCYYLAALAGIAMQDSQKIEEMFIDNGDGTYTVRFFNNGTADYVTVNRLLPTLDSGQFIFASVGGTLQQSWWSANPYYVQNTYNNVNNELWVALAEKAYAQINEAAWIGQDGTNSYKGIEEGRAQVASEHIAEVEGKYHDFSHSSVAAAIAAFTAGSAVFFSSDKNQHGTLIGSDKLVGGHAYLLTSYDSVNKTVTLFNPWNSGNSYDKDGYLTVSWNEVSTYFYAWREAS
>NC_019693.1|WP_156823922.1|5511766_5511907_-|hypothetical-protein
MNSAIARCIRTNAIAPESPSFVSYLFIREAEAKLCTDHASPEENFT
>NC_019693.1|WP_015150461.1|5511121_5511349_-|hypothetical-protein
MTLLIALFIVGWVAVAVLGTQAYFRGEQSKPIHERNWRSDSFETLAESITGTDIDYSKRVPAFEVDAYTSSNLPS
>NC_019693.1|WP_156823924.1|5538302_5538494_+|hypothetical-protein
MDSNSFLTIAIGPVDLDGRSCWCWVRDRLPASIDDPIIQRELREVLFQEWLQKQLKETTLRLD
>NC_019693.1|WP_015150470.1|5538576_5539479_+|hypothetical-protein
MTRFIHDQFAKQYLEELLSPFGTVETGKTIAAEVQEVDVLFIANPESNRDRSSLGLLGQIAGNQSIFEPFRNAVQPKQIRSCLAKLYAIQSNEERKANRDNTPLPEEEVITGWILTPTASSSLLDYFGATEDPIIGVKGVYSLARGLKMGLIAIHQLPVNPETLSLRLLGKGRVQQQAVNEIQGLPDDNPWKLAALELLYNLRTILEVRQDLEPDDQELIMELSPLYLQRLEDATQRGRQEGNQQGQRLMIESMLQVKFGEVDAELAQIIDPLIELTPLERTQLIMQLSRDEILTRFLNN
>NC_019693.1|WP_015150471.1|5540910_5544879_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MTLFMKPLLFPVALAGSLTLCWFAIVPTRTSAQIVPDRTLPENSRVTPDDNTFIIEGGTSTTGGTLFHSFEEFSVPTNTEALFNNTDQINQILTRITGASISNIDGILRANGNANLFFLNPNGIVFGPNARLELGGSFLATTGDRFVFADGSFFSASNPETLPLLTVNAPIGLQFGTTSGPINVLGIGHNLVPDELGAVDRSNRSDGLQVNPGNTLAILGSSVTLDGGNLIAESGRIEVGSVSAGSEIKLNSQEQGLIFDYQNVRGFQDVQLTEKASIDASGPGGGDIRVHGRNINLNDFSVVLSLTEGNESGQTLQVNASDSIKLNELSAILAETYGTGIGSTLNINTGLLLIENGSTISAGVNDGEPGNVLSINVRELILENGGQISASSFFENGKAGDIHIRASDSITASGEGEDISEEMRASGIFANQNDPLGTRPGGNITLETRNLTVDSGAQIAVGTIGFGQAGTLRVTALDSIELAGRAQDPEFSSGLFASTLGFGNAGNLIIETSRLIVRDGAVISVKGQTLNDLEMVWGIEDIDNLPEEALDFFGIENPTELALGQAGNLTINSPLILLNEQGIIRATTVAGDNANIQITTNNLQLRRGSNITTDASRLATGGNITIDTQTLVLGENSNITARATDGRGGNIQVNTTADIRSFDSAIDASSQRGIDGVVAINRPEVDPAAALVELEEDRINPVALVPRGCDVGSSDNSSRFIVSGWGGLPPSPREPRSGGNFIDNLDPLPARNYEGSGENLGNFSLGEAVPVQRISEASNWQLNEQGEVVLIAAVEKSSPDLPGIGCDGEALSPGLKNVETAASGIPESITVDRFNVVGNSVFSEAEVSQVLSPYTNRSLSFADLREARSAITNLYVEAGYITTGAYLPPQTVRENTVEIAVVPGMLREIQVNSNRLHNYVHDRLMVAIGNEPVNVNRIVEALRLLRLDPLIQEVQGELRAVPIPGQNILEVNIIEASPFSGTQLVLDNRRSPGVSTFRQQVQGNYNNLLGLGDRLFFSYARTEGSNTWEGSYIVPITPRNTTLGFRYSNGNSQIVESPFDRLDIEANSRLYELTLRQPFQRATPEYTREFALGLTASRQASETSLLGDRFPLSAGANNNGELRVSALRFFQDWTQRQPEQVLALRSTFSLGVDAFDATVNNNAPDSRFFAWRGQGQWVRSFGRDTLLFVRGDVQLSPDNLVSFEQIGLGGLDTVRGYRQDTLLTDNGVLGSVELRLPVFRFAGGNGLVQIAPFLDVGTGWNSAGQANPNTTSLVSLGLGLQLELGNQLTARLDFGKPLVDINSRNRTWQENGIHFSVKYNPF
>NC_019693.1|WP_015150472.1|5544830_5547686_+|CHAT-domain-containing-protein
MARKWHPFFGKVQSFLNRGWKFILISIFATITILNLQGGSPVLAYQPWGETVAQTPSFDGEMRLEEGSRFYENLRFAEAETAWRASVGLLSGEEKALGLSYLALAQLRQSKLDEADISIQESLRLLNQVTTPGTSERNQIIHARILTTAAQVNLARNQPELAAHALEQFAEATTIYEKLNQQEWVIASQINQAQAMQQLGMYREALKTLKNLENLILHHSDSEIPLSGLLSLGKTYRAIGVLDQSYCVLEAGKENPEIALELGNTAQAIGKRIKDQLDSVNEKTSEPIFTTEQGVENCTIPFKDIPLISAWDFYEKAQDFYQQSWNSPAVKPETQVQGMLNTLSLALDLKDAKELEEETKSNLERQAHELPPQVLQLIEILPSLNREKVYDRIHLARSLTRLNLEELSQNQLETAIAEAQELADQRAQAYAIGELGWMKQQQGNWTEAEQWTRQAMAITPPDAIDIRYQWEWQLGQILKEEGRTEEAIRHYTEAVDLLQRVRQNLVAIAAGMGEMNADLQFDFRDRVEPVYRELVGLLLDSQGNEVTSQDHIQTALGVIELLQVAELENFLQCDLQPEPQVQLARSVAEAKQKVAEKLNAIHQKKPDYAVIYPIIIQDKLEVILGLPGTPLVHYSNPSSDNIKKILADFRRQLIIPRDFEAVKNQSFQLYKMLINPFKSKIDNKSLLFILDVPLQSVPMGALYNKITEKYLIQTHTIRMTSSLQLLQIDAEKHPITEVLTAGIAQPRTERNIPFSSLDHVEQELDDIRKHFPGSQKLFEEKFTQSNLEQALSHQTFPAIHLATHGHFSSQRYLTFLLDGQTIIEVADFKRLFAEPSYLTTNPIQLLVLSACQTAQGDRKSALGIAGLTVSGQINNTIASLWSVKDQSTARLMNKFYEKLMEFSSPDLSQSDRTALALQEAQKSMIEEQESILRRRHHPSSWSPFILLSNAL
>NC_019693.1|WP_015150473.1|5547798_5548524_-|DUF928-domain-containing-protein
MKTSSSGNRFGFMFLSLFMIMINLPIQVLSNENNQNSPFRGRGRPSNVIGGGSRGNCEVTAEHQTLRLTALVPAEIGGVTQRERPTWWFYSPFNQRVYSPLQAQFIVTKDDKNFLPPIDVTLPEIPGFFPVSIPPDSPLEVNKWYMWTLLVICDPQDESKHIDINGWIKRIPEHEDSEEYLRWYDPLDSIAQTQCDNPDDREALQQWEERLSSVEDQLEPWDQKVWKEVRDQRMVCHRDLN
>NC_019693.1|WP_015150474.1|5548523_5550887_-|CHASE2-domain-containing-protein
MAKLVKLSLEGDLTSGYEVELIQISEEERDGKVLIEGIGGQLPAAAEIYECYQTWQQNYEQLDRIYRGGEFRFLGVETSSNVSLAKCQQLSQILEQKINDWLDAPGFRAIADRILTYLNPEEDIRFLIKTSDYNLWQIPWSAWIFFETHPNAEVVFSSFDAKYGEKPIKATPRKNVRILSVFGSDENINTKPDQEQIERLKSVGAEPTLIIKPRADHLRNLLWDKSWDILFFAGHGDRDKDSQKGKIYLNSNEYLTPSEFKNTLKTAIVDRNLKIVFLNSCLGLEFAYELVVDFKIPVVIAMREQIPDDAAQNFLQYFLLEYADNKRPLYVAVRRAKERIAEEFQDKYPGLNWLPVVCQNPAHIPLKWGDLYNKVSVKQAAVTSLFCTLMVVLARSLGFLQPLEFMTYDWLMSLRPLESVDERIVIITIDEQDIQYQINEGFKPSLASSFSHEALDRLLQKISPYQPRVVGLDIFYNIPFEGKSLQNQIESLNQLIGICQLGDETNPNNPPIPPPPGLTTIGFVDMPVDSDGVIRRQLYGAWPPEDCPTDFSFNLRVANSYLEQELNQTNLITVTQSDNMSINQVIFPILNRRYGGYQIKGDDLSGYQGLLNYRNARFHQRSLRGILQGESDQELDELIRDRIVLIGVTRPPRSDKHPTPLINDWRDNLYGVEIQAQKISHIISAVLDGRTLFWWWGEKTENLWIASWSLMGGVLVWKLRSPLKIGLGSIIAIGILGGICFLLLLEGGWIPLFPSACGFLLTVSVLNVNPKFYQFPQKYTLKIAQAI
>NC_019693.1|WP_015150475.1|5550926_5552138_-|DUF1822-family-protein
MNANVTHPFPPIAPDELYFNLSFEMQAQAWQKSRCHSNPIARNQAYLGHLCLQGFMSWVLERFEGNSQFVEPYVNHLESLWEFIEGVPIIVGKNRLMLIPSQTLNPDDLIVPREWIDIPELRADYYLSMQVNLDEEEENCWICVRGFVTDVEFENRATYTRSSRLYALSPENWHQDLTLLWETLGIHQAKSVSPLPSISYTTVKDAVRGLSPAALRSPRLRLQLPFAQWGGLMANETWRKELYQQRVKPPALTQWFQTQGSEISTELIAIGWQLYQEVFGGSQLAGTFRRAPVEPKAIASRVKQLELGEEAIALVIDLMEDTEGNLWISPQLRPFNPGDRTQCLPPNLNLALLDDEGTTQVEVRSETATNILQLPQPFCSSPGTEFVLSISLGNQTILEYFTI
>NC_019693.1|WP_015150476.1|5552163_5554281_-|hypothetical-protein
MPILPHVRCRTSLNEKLTTSLEIGFSHNKYQPQWVVKTDAHRSLEQLKKTDDFIQTLYKPEGEPEDWNRFVIYLAQRWQAEQLAGVYPGQPRQRAKGFIKKYELYPLLCAYLDEPAYRAVEKTAKSWKRLKSYTWEHWFSKVQDIINTPHEIIRILENFLHAAQESQGKVSMEFYFKRAFEYKILEKLEQFGISRASDWRLLCMAKESELRQSLKTQGISDLMIERYMFSWDYFKSVYKDNRVNHPGRKKGDRWPNPHQEDYAEVSRYYNQEKELTGVPLAVFQDTPKSSEQIAQWMQESVQALRDSALLDEVNINNPDVLDRLSLQKSVVSPTSSSKSSDLLGNVQEILTENLEQLNSRFAQAIAQGEKPDYIVKLLPLRYGMGLSQQDVGQIFGVHQSQISRRESDYIETLLSLFCQWLADKKGISLERINQDLNQWLSGGYAHPKFSTPIQGFLIETMTKSLSKPERSLLEKHYQKQKTIPQIASEHKLKTGEVEQTLDRAKHPLRRVLCIALWVETSTEKLIRQSYQDSIHSPNLLSDKILEGVATLTEEQQKILRYVYGTQLSQEEVTQKLNCTANELTRQLTASLKELQMILHLKLTELVTTTVKTWLKSHYQTKVLPRFPSRYCEEYQLLTLYYQQRLKPRKIASRLSVGYHVTIEEVVNQLSQAEGLFLEAIQYWCQQQLAISLSEGDLEKVLKKWF
>NC_019693.1|WP_015150477.1|5554384_5554945_-|hypothetical-protein
MGTTLARVEAYLDAWNWNYIVDRANSRIITAVRSEVLNPFQIVIELKEQGRFCRIYVPRLLQFHRHPYRELLLSTLLSLSWETKMLRWEYDSLGGEVRAGIELPLENAELESTQFYRCLSGLIQLIQDALPRLNSVMETGIDPVQCQRGEQLLLMLQEKMPRGFLDELDQAIVAHHSRPNIKQSMV
>NC_019693.1|WP_156823925.1|5555064_5555265_-|hypothetical-protein
MATVHPFRGEMPHRFASVSLLAIAFTLCTAPVRPQLPQPNAHSDYTRVAHDNLPGSHLPVGPLDLF

Crispr_ID: NC_019693_59

• CRISPR_ID: NC_019693_59
• CRISPR_location: 5586239-5586330
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: RT

Consensus repeat of NC_019693_59

Consensus_repeat	Method
TAGGGGCGCAATGCTTGCGCCCTCAATTG	CRISPRCasFinder

spacers of NC_019693_59

>59.1|5586268|34|NC_019693|CRISPRCasFinder
ATTACCAATTGAATGACGAAAAATCGTGATTTCG

CRISPR arrays and Neighbor proteins around NC_019693_59

CRISPR arrays

The CRISPR arrays of NC_019693_59

>merge|NC_019693|59|5586239-5586330|CRISPRCasFinder
TAGGGGCGCAATGCTTGCGCCCTCAATTGATTACCAATTGAATGACGAAAAATCGTGATTTCGTAGGGGCGCAATGCTTGCGCCCTCAATTG

>NC_019693|59|57|5586239-5586330|CRISPRCasFinder
TAGGGGCGCAATGCTTGCGCCCTCAATTG	ATTACCAATTGAATGACGAAAAATCGTGATTTCG
TAGGGGCGCAATGCTTGCGCCCTCAATTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_044197672.1|5581789_5583709_+|ATP-binding-protein	unknown	unknown	gnl|CDD|379062
NC_019693.1|WP_015150493.1|5576697_5578188_-|site-2-protease-family-protein	unknown	unknown	gnl|CDD|100081
NC_019693.1|WP_015150501.1|5588143_5589220_+|D-alanine--D-alanine-ligase	unknown	unknown	gnl|CDD|234993
NC_019693.1|WP_015150500.1|5586486_5586864_-|YccF-domain-containing-protein	unknown	unknown	gnl|CDD|236975
NC_019693.1|WP_015150496.1|5580013_5580769_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NC_019693.1|WP_044195663.1|5571528_5572260_+|DNA/RNA-nuclease-SfsA	unknown	unknown	gnl|CDD|234733
NC_019693.1|WP_015150503.1|5589780_5592351_-|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NC_019693.1|WP_015150508.1|5598726_5599599_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150497.1|5580854_5581292_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150494.1|5578191_5578848_+|hypothetical-protein	unknown	unknown	gnl|CDD|293813
NC_019693.1|WP_015150505.1|5594056_5595868_-|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173810
NC_019693.1|WP_052315781.1|5587204_5587651_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150507.1|5597114_5597894_-|HAD-IIB-family-hydrolase	unknown	unknown	gnl|CDD|223635
NC_019693.1|WP_015150506.1|5596160_5597084_+|RDD-family-protein	unknown	unknown	gnl|CDD|377640
NC_019693.1|WP_015150504.1|5593826_5594060_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150495.1|5579247_5579712_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150502.1|5589292_5589691_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150499.1|5583705_5585916_+|hypothetical-protein	unknown	unknown	gnl|CDD|238121
NC_019693.1|WP_044194328.1|5572638_5574396_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209
NC_019693.1|WP_044195666.1|5575238_5576585_-|FADH(2)-oxidizing-methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))--methyltransferase-TrmFO	unknown	unknown	gnl|CDD|235416

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_044194328.1|5572638_5574396_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	7.5e-46	151.1	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_044197672.1|5581789_5583709_+|ATP-binding-protein	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	0.000137298
NC_019693.1|WP_015150496.1|5580013_5580769_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	6.97021e-28
NC_019693.1|WP_044195663.1|5571528_5572260_+|DNA/RNA-nuclease-SfsA	gnl|CDD|234733	PRK00347, PRK00347, DNA/RNA nuclease SfsA.	7.28322e-106
NC_019693.1|WP_015150500.1|5586486_5586864_-|YccF-domain-containing-protein	gnl|CDD|236975	PRK11770, PRK11770, YccF domain-containing protein.	1.49646e-39
NC_019693.1|WP_015150493.1|5576697_5578188_-|site-2-protease-family-protein	gnl|CDD|100081	cd06160, S2P-M50_like_2, Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the S2P/M50 family of RIP proteases use proteolytic activity within the membrane to transfer information across membranes to integrate gene expression with physiologic stresses occurring in another cellular compartment. In eukaryotic cells they regulate such processes as sterol and lipid metabolism, and endoplasmic reticulum stress responses. In prokaryotes they regulate such processes as sporulation, cell division, stress response, and cell differentiation. This group includes bacterial, eukaryotic, and Archaeal S2P/M50s homologs with additional putative N- and C-terminal transmembrane spanning regions, relative to the core protein, and no PDZ domains.	1.86799e-58
NC_019693.1|WP_015150501.1|5588143_5589220_+|D-alanine--D-alanine-ligase	gnl|CDD|234993	PRK01966, ddl, D-alanine--D-alanine ligase.	0
NC_019693.1|WP_015150503.1|5589780_5592351_-|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	6.93652e-19
NC_019693.1|WP_015150505.1|5594056_5595868_-|S8-family-serine-peptidase	gnl|CDD|173810	cd07484, Peptidases_S8_Thermitase_like, Peptidase S8 family domain in Thermitase-like proteins. Thermitase is a non-specific, trypsin-related serine protease with a very high specific activity. It contains a subtilisin like domain. The tertiary structure of thermitase is similar to that of subtilisin BPN'. It contains a Asp/His/Ser catalytic triad. Members of the peptidases S8 (subtilisin and kexin) and S53 (sedolisin) clan include endopeptidases and exopeptidases. The S8 family has an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. Serine acts as a nucleophile, aspartate as an electrophile, and histidine as a base. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of subtilisin. The serine residue here is the nucleophilic equivalent of the serine residue in the S8 family, while glutamic acid has the same role here as the histidine base. However, the aspartic acid residue that acts as an electrophile is quite different. In S53 the it follows glutamic acid, while in S8 it precedes histidine. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. There is a great diversity in the characteristics of their members: some contain disulfide bonds, some are intracellular while others are extracellular, some function at extreme temperatures, and others at high or low pH values.	1.02149e-132
NC_019693.1|WP_044194328.1|5572638_5574396_-|group-II-intron-reverse-transcriptase/maturase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	6.87539e-123
NC_019693.1|WP_015150507.1|5597114_5597894_-|HAD-IIB-family-hydrolase	gnl|CDD|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	8.97179e-19
NC_019693.1|WP_015150506.1|5596160_5597084_+|RDD-family-protein	gnl|CDD|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	2.03944e-18
NC_019693.1|WP_015150499.1|5583705_5585916_+|hypothetical-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	9.09451e-108
NC_019693.1|WP_015150494.1|5578191_5578848_+|hypothetical-protein	gnl|CDD|293813	cd07727, YmaE-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis YmaE and related proteins; MBL-fold metallo hydrolase domain. Includes the uncharacterized Bacillus subtilis YmaE and Nostoc all1228 proteins.Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry. .	2.57628e-27
NC_019693.1|WP_044195666.1|5575238_5576585_-|FADH(2)-oxidizing-methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))--methyltransferase-TrmFO	gnl|CDD|235416	PRK05335, PRK05335, tRNA (uracil-5-)-methyltransferase Gid; Reviewed.	0

Protein sequences

>NC_019693.1|WP_015150499.1|5583705_5585916_+|hypothetical-protein
MTTKLGDWIQQQSSQKRLYILRHQILLWAKGKQVQRMKAWLTDWGFLEQKLGAVGITALIDDYDLLLPLLPAEEQPGLKRIQGALQLSAHVLAEDNSQLAGQLLGRLLSFSDPEILTLLQQAKQWRGKPWFRPLTAHLTPPGGPLLRTFSGHSSLVNAVAITPDGKQAVSASVDHTLKLWDLATGSELATLTGHSDEVYAVIITPDGKQAVSASRDKTLKLWDLATGSELATLTGHSDWVNAVAITPDGKQAVSASDDHTLKLWDLATGSELATLTGHSSGVNAVAITPDGKQAVSSSRDKTLKLWDLATGSELATLTGHSSGVNAVAITPDGKQAVSSSRDKTLKLWDLATGSELATLTGHSNSVNAVAITPDGKQAVSASDDKTLKLWDLATGSELATLIGHSNSVYAVAITPDGKQAVSASDDKTLKLWDLATGSELATLIGHSSMVNAVAITPDGKQAVSASRDNTLKLWDLATGSELATLIGHSNSVWAVAITPDGKQAVSASDDKTLKLWDLATGSELATLIGHSNSVWAVAITPDGKQAVSASDDKTLKLWDLATGSELATLIGHSNSVLAVAITPDGKQAVSASMDNTLKLWDLATESELATLIGHSRGVYAVAITPDGKQTVSASDDKTLKLWDLATGSELATLTGHSNSVNAVAITPDGKQAVSPSWDNTLKLWDLATAEVLATFTGDGRMHSCGMASDGVTVVAGDSSGRVYFLRVEGLESEAQC
>NC_019693.1|WP_044197672.1|5581789_5583709_+|ATP-binding-protein
MLQIIKEHKLLLGVTALLSIGSVVAGGATAIPLLAEFASPLLNSMAATKLLDLAKKLRDSSQVLTNEDLPKAAGRAIALGILHISQEDKYREIAPGLESLARKTEKYWLQIERDRQSPGDYLPIREPQLRYVFAANAAETAIATLDLESWQKLITWLMEQHQPHLPAEIGEYQDAIDAISQHLYKRFSHNLREVLKQDAREGGPAFSGMVLDLLRDNLAQTHQQALKQQDIIQILTHLETGIRDELGQLRGSFQQFFDLTKPRLPIRQECETLIADKIQDFVGRKYVFAAIRDFLHKNPKGYFILEADPGVGKSAILAKLVELSQGHCLTHFNSQGSGIIKPQQFLENICIQLIEGYHLDYPQLPEKTTEDGNVLARLLAEASKTLLPGEKLIVVVDALDEVDASSQTPGSNLLYLPDSLPDQVYFILSKRPKQLPLPLTDYDIPFDLMLYPAESARDARHYAEKRWQQSPQIQDWVTSRHSTPEQFFTELVAKSENNFMYLRYVLNDIDKGLYESETLDSLPFGLKRYYQKHWLLMGMNTDPLPIDKIRIIYVLSESPEPVSRPLLAELAGLSKSRVRSVLEEWEQFLRFQTIEREKCYSVYHASFSDFLNEQAEDSGIDLEDINRRMGDNLADGAPL
>NC_019693.1|WP_015150497.1|5580854_5581292_+|hypothetical-protein
MEQMTERIESIKAGAIAGCSLAVAWGITSFGNQLWLSPGVESWAIFPAWQRLWVSGGSAGVAGFLFGVTYRYIIRDDVNPHLKSGAVFAFGLVRVLAQIEVGLSHPSDIFPLGVMGIESILMFAIARVLLDAAIARHWVKPFSSF
>NC_019693.1|WP_015150496.1|5580013_5580769_+|class-I-SAM-dependent-methyltransferase
MAENKPLSLGEQNYQEFAERYAAAISTKPHNAYYERPATLSLLPNVNRLRVLDAGCGPGIYTQWLLDRGAEVVACDVTPKMVDITRQRVGDLAEVYCADLDQPLSFAGDAQFDLVICPLVLDYLLDWYPVFCEFFRVLKPGGILVFSCGHPTADYIYSQEQKGDGANYFEVEDFVMEWRLFGKPYPVIQSYRRPLQAILNPLIEAGLVLDKVLEPQPTDSFQVADAQGYEQLMRSPGFICVRSHKPGQSSS
>NC_019693.1|WP_015150495.1|5579247_5579712_+|hypothetical-protein
MSVATPYSNAPDVSTEDYLVVGLATCFLKQDGEIHQVKIVEPIPSAALEAILKGIPTSYEFACATTLGAILEGEQPKLLPEFPADAQFCDDFTERAISTVRTYQHRPQAREAIALGSIYRELNYSVERKRVLNSDNIVRAEDNVKQHEYTHKVL
>NC_019693.1|WP_015150494.1|5578191_5578848_+|hypothetical-protein
MPKQPRAVFDNIFAFSPNRETLGATAYLIVENNANILVDCPPWDESTAEFLNQQGGLDSLFLTHRGGISKVKEIQKATGCQVVIQEWEAYLLPELTVQTFEKDCTLSPNCQGIWTPGHSPGSSCLYYGGHGGVLFVGRHLLPNAQGEPMPLRTSKTFHWTRQIQSVKLLQEQFAPESLHYLCPGASTGFLRGKRVIDSAYQHLAAIDLQGLQQLEPIL
>NC_019693.1|WP_015150493.1|5576697_5578188_-|site-2-protease-family-protein
MILWLLLLGFITYIILRQRVAHLTHTPVWVLWLAVMAPAFLWMAWFFIHGDRSPLPKEVALGSFVVSPLIYWMLFFWGRRDMHSELEQDPGGDSDPESPRMKAVSRGFAPVNPQELRALNDGEEQELRDCFDWTVYALHQIDYRPQAVICRGQLRSPPESAYQKICAKIEDKFGDRFLIIFQEDFKGQPFFLLVPNPQQTLSQDELNKPLIALSLAGITLFTTTLFGTELVGFSLEEVQSDPSLLLQGLPYAVALMLILGIHESGHYLAAVFYKIKTTLPYFIPFPFLLGTFGAFIKIRSPMPNRKVLFDISIAGPLAGLVVTLPLLWWGLVHSTIVPIPENPGIFQITALDPKTSLILAFLSKLALGSQLTLTSAINLHPVAVAGYIGLIATALNLIPVGQLDGGHIIHAMFGQVKAVRIGQITRIAFLGIAWIHRLWVIWAILLFFMPIVDSPALNDVSELDNRRDLLGLLAIALLLAIVLPAPRLITQWLNII
>NC_019693.1|WP_044195666.1|5575238_5576585_-|FADH(2)-oxidizing-methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))--methyltransferase-TrmFO
MNDKQPVTVIGAGLAGTEAAWQIARAGVPVVLYEMRPVQMTPAHHTGEFAELVCSNSFGAKASDRAAGLLHEELRQLGSLVIGTADRHQVPAGGALAVDRGVFSHELTETLANHPLIDLRREEAPAIPQEGIVVLTTGPLTTPALATDLQRFTGMEYMSFFDAASPIVVGDSINLDIAFRASRYDKGDADYINCPMNKEQYLHFWQELCKAEQAELKEFDRETSKFFEACLPIEEMAKRGEDTMRYGPVKPVGLSDPRSETRPYAVVQLRQEDKAGQLWNMVGFQTNLRWGEQKRVFQLIPGLENAEFVRMGVMHRNTFINSPQLLDRTLQFKTRSTLLAAGQLTGTEGYTAATAGGWLAGTNAARLAQGLKPVWMPYTTMMGALFSFISSASPKHFQPMPPNFGILPPFPQKIKSKPERYGKYRDRSLSHLASWRTRLNVRVPALTT
>NC_019693.1|WP_044194328.1|5572638_5574396_-|group-II-intron-reverse-transcriptase/maturase
MTVAMNTVKTSLKTTETWNAIPWTKVQRKVFKLQKRIFQAAKSGQDAKARRLQKLLTSSYYARLLAVRKVTQDNQGKKTAGIDGVKSLKPKQRLELAKDLGKHSKAKALRRVWIPKPGRDEKRPLGIPIIRDRAEQALVKQALEPEWEARFEGTSYGFRPGRSAHDAIGRIYASINQGSYYVLDADITKCFDKINHEYLLSKLDCCLQHRRQIKQWLKAGVVDNGIFEDTESGTPQGGVISPLLANIALDGMARLIEELYPKRKGQKVKATLIRYADDFVVISPEIEIINQCKIALENWLKFVGLELKPEKTKICHTLREIEVNGEKVTPGFDFLGFTIRQYPVGKYKSGKTGGANSRLIGHKTHIKPSAKAIKAHSEALKGVIKNHKTAPQAALISRLNPIIRGWSNYYSGVVSMETFNQMDHNIWQQLRAWTVSRCGQANLEKLRKYFHKVTVKIGNGKERNEKWLFQAKDGLSLWKHSYTQITRHTLVKPEASPYDGNWSYWATRRGTSLEVPMRVAKLLKKHSGRCSRCGQYFAMEDLMEVDHIQPLSMGGKDEYRNLQLLHRHCHDKKTAEDMQNVKSYQ
>NC_019693.1|WP_044195663.1|5571528_5572260_+|DNA/RNA-nuclease-SfsA
MSEFVYTYPCLFPGTLLKRYKRFLADIKLDTGEEITAHCANPGKMLGLSAPGSRVMVSLSTNIKRKLPYSLELVAAEENPTTWVGVNTSLPNQVIKLALAARLFPGLGAYETIKPEVVYGRDRKSRVDFFLTGTEGTTPIYLEVKNVTWAQGEKALFPDAITTRGHKHLLELVDVMETHSARAVALFFISRGDCEVFGPGDTADPLYGKLLREAVAKGLEILPCRFELSPAGVRFLGLAEVAF
>NC_019693.1|WP_015150500.1|5586486_5586864_-|YccF-domain-containing-protein
MILIGNIIWLIFGGFITGLGYIIGGIGMCLTIVGIPFGVETIKLGIASMTPFGREIVEDDNPNSTLKIVLNVIWIFLFGWEIAIAHLVLAALFFVSLIGLPFAEQHIKLVAIALFPFGRDLRKVR
>NC_019693.1|WP_052315781.1|5587204_5587651_+|hypothetical-protein
MNKPAIALLGIGMIAVIGIAVVLVNPEDSNSVTAGQGSEIVQTEGTQDQSGAIAELPEAIRENVLDAVAEQTGEGRSQFEIVAAQRRSWPDGCLGLTEPGSFCTQIVVSGWEVTASDGEETWVYRTDRNGSQVMLDTAASSAYELREP
>NC_019693.1|WP_015150501.1|5588143_5589220_+|D-alanine--D-alanine-ligase
MAKLRVGLLFGGRSGEHEVSIISARAIAKALAGESNAEKYETLPFYIDKDGLWHSPAVAQQVLDAGVPRNEGGETGDRAKLWQFPAEAGTVEVWFPILHGPNGEDGTIQGLLTLMQVPFVGTGVMGSAVGMDKLAMKTAFSRADLPQVKYMAVTRSQVWSNPCVFPKLCDEIEQNLGYPCFVKPANLGSSVGISKVRSRSELEAALDSAASYDRRLIVEAGVVAREVECAVLGNDNAKASVVGEITYESDFYDYETKYTDGKASLFIPSELPEAVAAQIQEMAIRAFEAVDGAGLSRVDFFYVEATGEIFINEINTLPGFTALSMYPQLWAKTGVSFTELVDRLIELAIARHTDKSKE
>NC_019693.1|WP_015150502.1|5589292_5589691_+|hypothetical-protein
MSSRLLKPFTVSDRRQINRLRAFMPNRDSQLARLRELSGSQDAHLDYLRRLREQGSRPRLPEGAGGHPRRVRAGRKRTASGSLVGFLQRQPWVLGLLAWVLLMGMAWSSWNVLVSPGFTEVPEAPVSTPDEG
>NC_019693.1|WP_015150503.1|5589780_5592351_-|CHAT-domain-containing-protein
MSQKFEELHISVTPVGDDKYLVRTEQAPKGVLPAEEQVVWPVEGWLRQATKLMEDPLSMLMRLNDQPDSSSNSPTANSERTTLGNLVELGQELYQALFQGSLLDRMTSAQAIAHNQGNVLRLRLGLKGPHLPRLPWEVIHEETRAIATGKDLVFSRYQPTLAPVALPGNTGDRVKILMVLAAPTDRENLALKREAVHLQEDLKARWRSGTPVTGKPPQIQLDILEQPNREELTRALEQNHYQVLHYSGHSDVGAGGGELYLVNRKTGLSEVLTGNDLAGLLVNAGIRMAVFNSCRGAYTASSDPTDATGRRSLAEALVKRGVPGVLAMAERITDDVALTLTRLFYYNIKQGYPVDLSLNRARQGLMSAYGSHELYWALPVLYLHPEFDGYLTSAQETPENPRTTVGDRPLPRQTAPIPQEIAAASSLSPFSTPSNSHSRDTLLDFSTIPPSRTGTMTVQSAFAEDDSEFLDEGDLEGVYEDIMYDELDEDEAVAVVSELFREMVGEIDPEIDAVHRQNSQVQKAFDILEETITEELPPTAKTPPYSTPNWPLPATDAPLTQRRQNALSAVKFFGYKWRVAIGATVAIAIAGAGFWTGQTRFSATTPGPGTLFPPTASIALESPLSSGDRANFSQLQTPEVGKLAFAYFNEGDAIAGQKAVEELLQPQRSALNYAEAVLSGVPEPHKFDSSITFLWGRLAWQAVLSGNPKYSLDDVRRYWTRAVQQEPNNPTYYNALGFAYYADGNFKKAEDAWMESLKLLEKMPLIGAKNSTTPESAPLESYDALTAYAGFSLILSRSASDLPPGDRAEVLNKAIKLRKIVLNADPLSFQPDALATDWMWPESALEDWRSLLMTRE
>NC_019693.1|WP_015150504.1|5593826_5594060_-|hypothetical-protein
MSINVKGTIERKNIGPGAWALVSDSGETYEIYQGAPADLLKAGQKVKVKGQVRDDVMTMAMIGPVLEVKSFEAIASD
>NC_019693.1|WP_015150505.1|5594056_5595868_-|S8-family-serine-peptidase
MKKLLLLSLFIVGLSFALFNFKGLANQGTFESIVLDFREDLPLVEVKQQVNAIASEYGVVPRLNSQFSVDDHFYVVNGDRELLKTLKKSDVSEYTEYIEPAYEYQTLDIPNDPFYAQQWNLRSINVEKAWSDTKGSGITVAVIDTGVSRVPDLKNTKFVKGYDFVNNRELADDDNGHGTHVAGTIAQTTNNGYGVAGVAYEASIMPLKVLSASGGGNVADIAEAIKFAADNGADVINMSLGGAGESNAMKEAIAYAHNKGVVIIAAAGNEQRNSASYPARYVNVIGVAAIDSTGQKAPYSNFGAGVDISAPGGDTTNGDEGGILQETISFDPDTNLPGFAFQAYQGTSMAAPHVAGVAALIKASGITDPEKITAILKESAREVKEDPLNHFGAGHLDASTAVALAKGGQFDFGHFFSDFFRWLRDNGYLNPRFWIDGGVYALLPKVLMVVGSYLIAWLLKMYFPFSWTMSMATGLVAGSSGLFVFRGFYIFDLPQWPFRILGSSIPELGTAISGSSAFNPLFASVIIPVGLILLLLGHPQWKWFAIGSTIGVATCLGISAVLAPAPTLLWIGSGIGARAFLLVNACLCLALARLAMKDEGQIA
>NC_019693.1|WP_015150506.1|5596160_5597084_+|RDD-family-protein
MLMASYPAQSLFPGFFRRIIAAVIDFILIALVWFSVGLGINFLPRTGVNTITFMALDVSRIFIVFLVFITYFTLLEATLGWTLGKLIFQEEVVTLRGRRPSLLQALVRNIFKPVDMLLLLGPLLMSPKTQTLGDRYARTLVINRDAGVPGIIVEDRYIFTFKKIIGIILLLVSLAGLGIGFSLMRTYLPEIRSVNQAATNHFMRLEKGIAINQNVRAAYENASSQLREQMTFEEYQQRLQENPFLPLALERRQEIKFNQWTFQEEEGQRVAAVVKGNLESLFEIEVNLAKEQNQWKFVSGNFMPTGQ
>NC_019693.1|WP_015150507.1|5597114_5597894_-|HAD-IIB-family-hydrolase
MKSLPLSQLQAHHSLGRVAVVATDLDGTLTHQGKFTPGLLQALEALAAASVAVVIVTGRSAGWVSGLVSYLPVVGAIAENGGIFYPSNGTPVLLTAIADLKRHRQQLGAGFAHLLTEFPHLRETEDNPFRVTDWTFEVAGLTSENLQRLRSLCAELGWGFTFSTVHCHIKPHQQDKALALMQVLGDCFPDYSSDRVVTVGDSPNDESLFDQTLFPFSVGVANLAEYLDLLTHHPAYLTDLPESEGFCELVRTILAAQLP
>NC_019693.1|WP_015150508.1|5598726_5599599_+|hypothetical-protein
MSSPIILVQPTLAQAPEANDSKFPLSSDQLWMSVSGGLLLLLIASFVFQKVQLEQLKKKIKFDEFKNKELQKKLKMSLEAITKMEKNPDLIHSREFNLDYLRMRMEEENFHFAVVNQIKVKVKEKISVALRPNAETRGSGRQVDEIFDVEYHLGDVAKSKKRVLFRIQIKLTKLPTQATSKTISQIIDCLETYLSARDDHDTWQPTIQGRVAYIHWDQKAKPTPLLVLEQSNEGVNVTFRTTTARRVSASDTSDTGAMTGATSITNATTRRGKTGTKTKTPGNAGKKPRR

Crispr_ID: NC_019693_60

• CRISPR_ID: NC_019693_60
• CRISPR_location: 5593115-5593211
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_60

Consensus_repeat	Method
TAAATTTAATGACGAAAAATCAGGGTTTCTTG	CRISPRCasFinder

spacers of NC_019693_60

>60.1|5593147|33|NC_019693|CRISPRCasFinder
GACAGGCGATCACTCTCGCGCCCCTACAAGAGG

CRISPR arrays and Neighbor proteins around NC_019693_60

CRISPR arrays

The CRISPR arrays of NC_019693_60

>merge|NC_019693|60|5593115-5593211|CRISPRCasFinder
TAAATTTAATGACGAAAAATCAGGGTTTCTTGGACAGGCGATCACTCTCGCGCCCCTACAAGAGGTAAATTTAATGACGAAAAATCAGGGTTTCTTG

>NC_019693|60|58|5593115-5593211|CRISPRCasFinder
TAAATTTAATGACGAAAAATCAGGGTTTCTTG	GACAGGCGATCACTCTCGCGCCCCTACAAGAGG
TAAATTTAATGACGAAAAATCAGGGTTTCTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_044197680.1|5600566_5601724_-|FtsX-like-permease-family-protein	unknown	unknown	gnl|CDD|130253
NC_019693.1|WP_015150505.1|5594056_5595868_-|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173810
NC_019693.1|WP_015150496.1|5580013_5580769_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NC_019693.1|WP_015150512.1|5603970_5605242_-|aspartate-aminotransferase-family-protein	unknown	unknown	gnl|CDD|235056
NC_019693.1|WP_015150511.1|5601739_5603749_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|213754
NC_019693.1|WP_015150500.1|5586486_5586864_-|YccF-domain-containing-protein	unknown	unknown	gnl|CDD|236975
NC_019693.1|WP_044197672.1|5581789_5583709_+|ATP-binding-protein	unknown	unknown	gnl|CDD|379062
NC_019693.1|WP_015150501.1|5588143_5589220_+|D-alanine--D-alanine-ligase	unknown	unknown	gnl|CDD|234993
NC_019693.1|WP_015150503.1|5589780_5592351_-|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NC_019693.1|WP_015150508.1|5598726_5599599_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150502.1|5589292_5589691_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_052315781.1|5587204_5587651_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823926.1|5605909_5607523_+|sodium:proton-antiporter	unknown	unknown	gnl|CDD|223104
NC_019693.1|WP_044197678.1|5599752_5600490_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|274374
NC_019693.1|WP_015150507.1|5597114_5597894_-|HAD-IIB-family-hydrolase	unknown	unknown	gnl|CDD|223635
NC_019693.1|WP_015150506.1|5596160_5597084_+|RDD-family-protein	unknown	unknown	gnl|CDD|377640
NC_019693.1|WP_015150504.1|5593826_5594060_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150495.1|5579247_5579712_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150499.1|5583705_5585916_+|hypothetical-protein	unknown	unknown	gnl|CDD|238121
NC_019693.1|WP_015150497.1|5580854_5581292_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_044197680.1|5600566_5601724_-|FtsX-like-permease-family-protein	gnl|CDD|130253	TIGR01185, membrane_spanning_subunit, DevC protein. This model describes a predicted membrane subunit, DevC, of an ABC transporter known so far from two species of cyanobacteria. Some experimental data from mutational analysis suggest that this protein along with DevA and DevB encoded in the same operon may be involved in the transport/export of glycolipids. [Transport and binding proteins, Other].	8.08549e-178
NC_019693.1|WP_015150505.1|5594056_5595868_-|S8-family-serine-peptidase	gnl|CDD|173810	cd07484, Peptidases_S8_Thermitase_like, Peptidase S8 family domain in Thermitase-like proteins. Thermitase is a non-specific, trypsin-related serine protease with a very high specific activity. It contains a subtilisin like domain. The tertiary structure of thermitase is similar to that of subtilisin BPN'. It contains a Asp/His/Ser catalytic triad. Members of the peptidases S8 (subtilisin and kexin) and S53 (sedolisin) clan include endopeptidases and exopeptidases. The S8 family has an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. Serine acts as a nucleophile, aspartate as an electrophile, and histidine as a base. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of subtilisin. The serine residue here is the nucleophilic equivalent of the serine residue in the S8 family, while glutamic acid has the same role here as the histidine base. However, the aspartic acid residue that acts as an electrophile is quite different. In S53 the it follows glutamic acid, while in S8 it precedes histidine. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. There is a great diversity in the characteristics of their members: some contain disulfide bonds, some are intracellular while others are extracellular, some function at extreme temperatures, and others at high or low pH values.	1.02149e-132
NC_019693.1|WP_015150496.1|5580013_5580769_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	6.97021e-28
NC_019693.1|WP_015150511.1|5601739_5603749_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	gnl|CDD|213754	TIGR02971, devB-like_secretion_protein, ABC exporter membrane fusion protein, DevB family. Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. DevB from Anabaena sp. strain PCC 7120 is partially characterized as a membrane fusion protein of the DevBCA ABC exporter, probably a glycolipid exporter, required for heterocyst formation. Most Cyanobacteria have one member only, but Nostoc sp. PCC 7120 has seven members.	2.70617e-46
NC_019693.1|WP_015150500.1|5586486_5586864_-|YccF-domain-containing-protein	gnl|CDD|236975	PRK11770, PRK11770, YccF domain-containing protein.	1.49646e-39
NC_019693.1|WP_044197678.1|5599752_5600490_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|274374	TIGR02982, heterocyst_DevA, ABC exporter ATP-binding subunit, DevA family. Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.	2.03748e-145
NC_019693.1|WP_015150501.1|5588143_5589220_+|D-alanine--D-alanine-ligase	gnl|CDD|234993	PRK01966, ddl, D-alanine--D-alanine ligase.	0
NC_019693.1|WP_015150503.1|5589780_5592351_-|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	6.93652e-19
NC_019693.1|WP_044197672.1|5581789_5583709_+|ATP-binding-protein	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	0.000137298
NC_019693.1|WP_156823926.1|5605909_5607523_+|sodium:proton-antiporter	gnl|CDD|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	1.99671e-76
NC_019693.1|WP_015150507.1|5597114_5597894_-|HAD-IIB-family-hydrolase	gnl|CDD|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	8.97179e-19
NC_019693.1|WP_015150512.1|5603970_5605242_-|aspartate-aminotransferase-family-protein	gnl|CDD|235056	PRK02627, PRK02627, acetylornithine aminotransferase; Provisional.	0
NC_019693.1|WP_015150506.1|5596160_5597084_+|RDD-family-protein	gnl|CDD|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	2.03944e-18
NC_019693.1|WP_015150499.1|5583705_5585916_+|hypothetical-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	9.09451e-108

Protein sequences

>NC_019693.1|WP_015150503.1|5589780_5592351_-|CHAT-domain-containing-protein
MSQKFEELHISVTPVGDDKYLVRTEQAPKGVLPAEEQVVWPVEGWLRQATKLMEDPLSMLMRLNDQPDSSSNSPTANSERTTLGNLVELGQELYQALFQGSLLDRMTSAQAIAHNQGNVLRLRLGLKGPHLPRLPWEVIHEETRAIATGKDLVFSRYQPTLAPVALPGNTGDRVKILMVLAAPTDRENLALKREAVHLQEDLKARWRSGTPVTGKPPQIQLDILEQPNREELTRALEQNHYQVLHYSGHSDVGAGGGELYLVNRKTGLSEVLTGNDLAGLLVNAGIRMAVFNSCRGAYTASSDPTDATGRRSLAEALVKRGVPGVLAMAERITDDVALTLTRLFYYNIKQGYPVDLSLNRARQGLMSAYGSHELYWALPVLYLHPEFDGYLTSAQETPENPRTTVGDRPLPRQTAPIPQEIAAASSLSPFSTPSNSHSRDTLLDFSTIPPSRTGTMTVQSAFAEDDSEFLDEGDLEGVYEDIMYDELDEDEAVAVVSELFREMVGEIDPEIDAVHRQNSQVQKAFDILEETITEELPPTAKTPPYSTPNWPLPATDAPLTQRRQNALSAVKFFGYKWRVAIGATVAIAIAGAGFWTGQTRFSATTPGPGTLFPPTASIALESPLSSGDRANFSQLQTPEVGKLAFAYFNEGDAIAGQKAVEELLQPQRSALNYAEAVLSGVPEPHKFDSSITFLWGRLAWQAVLSGNPKYSLDDVRRYWTRAVQQEPNNPTYYNALGFAYYADGNFKKAEDAWMESLKLLEKMPLIGAKNSTTPESAPLESYDALTAYAGFSLILSRSASDLPPGDRAEVLNKAIKLRKIVLNADPLSFQPDALATDWMWPESALEDWRSLLMTRE
>NC_019693.1|WP_015150502.1|5589292_5589691_+|hypothetical-protein
MSSRLLKPFTVSDRRQINRLRAFMPNRDSQLARLRELSGSQDAHLDYLRRLREQGSRPRLPEGAGGHPRRVRAGRKRTASGSLVGFLQRQPWVLGLLAWVLLMGMAWSSWNVLVSPGFTEVPEAPVSTPDEG
>NC_019693.1|WP_015150501.1|5588143_5589220_+|D-alanine--D-alanine-ligase
MAKLRVGLLFGGRSGEHEVSIISARAIAKALAGESNAEKYETLPFYIDKDGLWHSPAVAQQVLDAGVPRNEGGETGDRAKLWQFPAEAGTVEVWFPILHGPNGEDGTIQGLLTLMQVPFVGTGVMGSAVGMDKLAMKTAFSRADLPQVKYMAVTRSQVWSNPCVFPKLCDEIEQNLGYPCFVKPANLGSSVGISKVRSRSELEAALDSAASYDRRLIVEAGVVAREVECAVLGNDNAKASVVGEITYESDFYDYETKYTDGKASLFIPSELPEAVAAQIQEMAIRAFEAVDGAGLSRVDFFYVEATGEIFINEINTLPGFTALSMYPQLWAKTGVSFTELVDRLIELAIARHTDKSKE
>NC_019693.1|WP_052315781.1|5587204_5587651_+|hypothetical-protein
MNKPAIALLGIGMIAVIGIAVVLVNPEDSNSVTAGQGSEIVQTEGTQDQSGAIAELPEAIRENVLDAVAEQTGEGRSQFEIVAAQRRSWPDGCLGLTEPGSFCTQIVVSGWEVTASDGEETWVYRTDRNGSQVMLDTAASSAYELREP
>NC_019693.1|WP_015150500.1|5586486_5586864_-|YccF-domain-containing-protein
MILIGNIIWLIFGGFITGLGYIIGGIGMCLTIVGIPFGVETIKLGIASMTPFGREIVEDDNPNSTLKIVLNVIWIFLFGWEIAIAHLVLAALFFVSLIGLPFAEQHIKLVAIALFPFGRDLRKVR
>NC_019693.1|WP_015150499.1|5583705_5585916_+|hypothetical-protein
MTTKLGDWIQQQSSQKRLYILRHQILLWAKGKQVQRMKAWLTDWGFLEQKLGAVGITALIDDYDLLLPLLPAEEQPGLKRIQGALQLSAHVLAEDNSQLAGQLLGRLLSFSDPEILTLLQQAKQWRGKPWFRPLTAHLTPPGGPLLRTFSGHSSLVNAVAITPDGKQAVSASVDHTLKLWDLATGSELATLTGHSDEVYAVIITPDGKQAVSASRDKTLKLWDLATGSELATLTGHSDWVNAVAITPDGKQAVSASDDHTLKLWDLATGSELATLTGHSSGVNAVAITPDGKQAVSSSRDKTLKLWDLATGSELATLTGHSSGVNAVAITPDGKQAVSSSRDKTLKLWDLATGSELATLTGHSNSVNAVAITPDGKQAVSASDDKTLKLWDLATGSELATLIGHSNSVYAVAITPDGKQAVSASDDKTLKLWDLATGSELATLIGHSSMVNAVAITPDGKQAVSASRDNTLKLWDLATGSELATLIGHSNSVWAVAITPDGKQAVSASDDKTLKLWDLATGSELATLIGHSNSVWAVAITPDGKQAVSASDDKTLKLWDLATGSELATLIGHSNSVLAVAITPDGKQAVSASMDNTLKLWDLATESELATLIGHSRGVYAVAITPDGKQTVSASDDKTLKLWDLATGSELATLTGHSNSVNAVAITPDGKQAVSPSWDNTLKLWDLATAEVLATFTGDGRMHSCGMASDGVTVVAGDSSGRVYFLRVEGLESEAQC
>NC_019693.1|WP_044197672.1|5581789_5583709_+|ATP-binding-protein
MLQIIKEHKLLLGVTALLSIGSVVAGGATAIPLLAEFASPLLNSMAATKLLDLAKKLRDSSQVLTNEDLPKAAGRAIALGILHISQEDKYREIAPGLESLARKTEKYWLQIERDRQSPGDYLPIREPQLRYVFAANAAETAIATLDLESWQKLITWLMEQHQPHLPAEIGEYQDAIDAISQHLYKRFSHNLREVLKQDAREGGPAFSGMVLDLLRDNLAQTHQQALKQQDIIQILTHLETGIRDELGQLRGSFQQFFDLTKPRLPIRQECETLIADKIQDFVGRKYVFAAIRDFLHKNPKGYFILEADPGVGKSAILAKLVELSQGHCLTHFNSQGSGIIKPQQFLENICIQLIEGYHLDYPQLPEKTTEDGNVLARLLAEASKTLLPGEKLIVVVDALDEVDASSQTPGSNLLYLPDSLPDQVYFILSKRPKQLPLPLTDYDIPFDLMLYPAESARDARHYAEKRWQQSPQIQDWVTSRHSTPEQFFTELVAKSENNFMYLRYVLNDIDKGLYESETLDSLPFGLKRYYQKHWLLMGMNTDPLPIDKIRIIYVLSESPEPVSRPLLAELAGLSKSRVRSVLEEWEQFLRFQTIEREKCYSVYHASFSDFLNEQAEDSGIDLEDINRRMGDNLADGAPL
>NC_019693.1|WP_015150497.1|5580854_5581292_+|hypothetical-protein
MEQMTERIESIKAGAIAGCSLAVAWGITSFGNQLWLSPGVESWAIFPAWQRLWVSGGSAGVAGFLFGVTYRYIIRDDVNPHLKSGAVFAFGLVRVLAQIEVGLSHPSDIFPLGVMGIESILMFAIARVLLDAAIARHWVKPFSSF
>NC_019693.1|WP_015150496.1|5580013_5580769_+|class-I-SAM-dependent-methyltransferase
MAENKPLSLGEQNYQEFAERYAAAISTKPHNAYYERPATLSLLPNVNRLRVLDAGCGPGIYTQWLLDRGAEVVACDVTPKMVDITRQRVGDLAEVYCADLDQPLSFAGDAQFDLVICPLVLDYLLDWYPVFCEFFRVLKPGGILVFSCGHPTADYIYSQEQKGDGANYFEVEDFVMEWRLFGKPYPVIQSYRRPLQAILNPLIEAGLVLDKVLEPQPTDSFQVADAQGYEQLMRSPGFICVRSHKPGQSSS
>NC_019693.1|WP_015150495.1|5579247_5579712_+|hypothetical-protein
MSVATPYSNAPDVSTEDYLVVGLATCFLKQDGEIHQVKIVEPIPSAALEAILKGIPTSYEFACATTLGAILEGEQPKLLPEFPADAQFCDDFTERAISTVRTYQHRPQAREAIALGSIYRELNYSVERKRVLNSDNIVRAEDNVKQHEYTHKVL
>NC_019693.1|WP_015150504.1|5593826_5594060_-|hypothetical-protein
MSINVKGTIERKNIGPGAWALVSDSGETYEIYQGAPADLLKAGQKVKVKGQVRDDVMTMAMIGPVLEVKSFEAIASD
>NC_019693.1|WP_015150505.1|5594056_5595868_-|S8-family-serine-peptidase
MKKLLLLSLFIVGLSFALFNFKGLANQGTFESIVLDFREDLPLVEVKQQVNAIASEYGVVPRLNSQFSVDDHFYVVNGDRELLKTLKKSDVSEYTEYIEPAYEYQTLDIPNDPFYAQQWNLRSINVEKAWSDTKGSGITVAVIDTGVSRVPDLKNTKFVKGYDFVNNRELADDDNGHGTHVAGTIAQTTNNGYGVAGVAYEASIMPLKVLSASGGGNVADIAEAIKFAADNGADVINMSLGGAGESNAMKEAIAYAHNKGVVIIAAAGNEQRNSASYPARYVNVIGVAAIDSTGQKAPYSNFGAGVDISAPGGDTTNGDEGGILQETISFDPDTNLPGFAFQAYQGTSMAAPHVAGVAALIKASGITDPEKITAILKESAREVKEDPLNHFGAGHLDASTAVALAKGGQFDFGHFFSDFFRWLRDNGYLNPRFWIDGGVYALLPKVLMVVGSYLIAWLLKMYFPFSWTMSMATGLVAGSSGLFVFRGFYIFDLPQWPFRILGSSIPELGTAISGSSAFNPLFASVIIPVGLILLLLGHPQWKWFAIGSTIGVATCLGISAVLAPAPTLLWIGSGIGARAFLLVNACLCLALARLAMKDEGQIA
>NC_019693.1|WP_015150506.1|5596160_5597084_+|RDD-family-protein
MLMASYPAQSLFPGFFRRIIAAVIDFILIALVWFSVGLGINFLPRTGVNTITFMALDVSRIFIVFLVFITYFTLLEATLGWTLGKLIFQEEVVTLRGRRPSLLQALVRNIFKPVDMLLLLGPLLMSPKTQTLGDRYARTLVINRDAGVPGIIVEDRYIFTFKKIIGIILLLVSLAGLGIGFSLMRTYLPEIRSVNQAATNHFMRLEKGIAINQNVRAAYENASSQLREQMTFEEYQQRLQENPFLPLALERRQEIKFNQWTFQEEEGQRVAAVVKGNLESLFEIEVNLAKEQNQWKFVSGNFMPTGQ
>NC_019693.1|WP_015150507.1|5597114_5597894_-|HAD-IIB-family-hydrolase
MKSLPLSQLQAHHSLGRVAVVATDLDGTLTHQGKFTPGLLQALEALAAASVAVVIVTGRSAGWVSGLVSYLPVVGAIAENGGIFYPSNGTPVLLTAIADLKRHRQQLGAGFAHLLTEFPHLRETEDNPFRVTDWTFEVAGLTSENLQRLRSLCAELGWGFTFSTVHCHIKPHQQDKALALMQVLGDCFPDYSSDRVVTVGDSPNDESLFDQTLFPFSVGVANLAEYLDLLTHHPAYLTDLPESEGFCELVRTILAAQLP
>NC_019693.1|WP_015150508.1|5598726_5599599_+|hypothetical-protein
MSSPIILVQPTLAQAPEANDSKFPLSSDQLWMSVSGGLLLLLIASFVFQKVQLEQLKKKIKFDEFKNKELQKKLKMSLEAITKMEKNPDLIHSREFNLDYLRMRMEEENFHFAVVNQIKVKVKEKISVALRPNAETRGSGRQVDEIFDVEYHLGDVAKSKKRVLFRIQIKLTKLPTQATSKTISQIIDCLETYLSARDDHDTWQPTIQGRVAYIHWDQKAKPTPLLVLEQSNEGVNVTFRTTTARRVSASDTSDTGAMTGATSITNATTRRGKTGTKTKTPGNAGKKPRR
>NC_019693.1|WP_044197678.1|5599752_5600490_-|ATP-binding-cassette-domain-containing-protein
MNAHHASNFNSQPISSRPSAVVEIENVNHYFGKGTLRKQILFDIKLTIYSGEIVLMTGPSGSGKTTLLTLMGGLRSTQEGSLKVCNQQLCGASQNKLVQVRRNIGYIFQAHNLLNCLTARQNVQMSLDLHSQPGDESKMKAKATAMLESVGLREWVDYYPENLSGGQKQRVAIARALASHPQLVLADEPTAALDSKSGRDVVELMQRLAKDQGCTILLVTHDPRILDIADRIVQMEDGRLKEGWG
>NC_019693.1|WP_044197680.1|5600566_5601724_-|FtsX-like-permease-family-protein
MFRKIPLAWLQLSREKSRLLVAIAGIAFADILMFMQLGFRDALFDSSTRLHQSLTGDIVLISPRSQALISMQSFSRRRLYQTLAVPEVQAVSPLYLAIGSWKNPVDKSDRSILVLGIDPTKSVFNMPEVRANLDKIKPLDIGLFDRDARSEFGPIPQLLQEGPAVKTEVGGRRIEVRGLFSLGASFGADGSLITSDLTFLKLFKRRSIHEVDVGLIHLKPGANVEAVIAQIQSRLPPDVLVLSHQGFIEREQNYWKTRTAIGFVFTLGTIMGFMVGIAIVYQILYTDVASHLAEYATLKAMGYADWYFVGVVLQEAVILAVLGYIPAFAIANFLLYTLTRNATRLPIAMTPERAVLVLVLTLIMCAISGAVALRKLRDADPADIF
>NC_019693.1|WP_015150511.1|5601739_5603749_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit
MGHESVQDKDKKPDRQFTASSVPVADASLKTQAQVGRTPLERVGFLPPWVTLILVIAAIAIGGYSIYTLLQTRPVTQESETPTPIETPPTLQYVSALGRVEPGSQVIQVSAPNAMQGDRLGQLLIEEGDRVRADQTIAILDSRDRLAAQLEQAKQQVKIAQAKLAQVKAGAKSGDIAAQEAAIARLQAQIPRDLAVQDATIARLRAQVEGDIAAQGATVDRFSAQLEGNVTAREAGISRLQAELQGQILTQEATIARLQAELTGQRAAQQATISRLEAQIQGDRAVQQATIARLQAEREERLAAQQAVISQLQAKLENAGIEFRRYEHLYLEGGISASVYDTKRLDVEVALQEVKAAQARLEELDRTTRQQQLEAIATLEKINETGAKLLEEARATLTKIEGTVGKQIEEARTNLQRVQATAAEQLQEEQAVLTQLGRTGQAELSEAEVKQQQLQKVGREQLNEAVVTRDRIRATGEQELQEARSILESISEVRTVDVQLAEAEVDSAIAVEAEAQARLDEAYVRSPIEGRVLAINTRPGESITQDQGIVAIAQTDRMFIVAEVYETDIRYVRLGQRAAITSQAVDGELLGTVDRIGLQIGKKDVLETDPTADTDARVVEVKIRLDPQDSERVSGLTNLQVEVIIATMSSPMVPPSPSVPADPPVIIPE
>NC_019693.1|WP_015150512.1|5603970_5605242_-|aspartate-aminotransferase-family-protein
MSPETLISQPNLETNPSVFDPAEFDAAVMTTYGRFPLALERGQGCRVWDTEGRAYLDFVAGIATCTLGHAHPAMVKAVTEQIQKLHHVSNLYYIPEQGALAQWLVAHSCADRVFFCNSGAEANEGAIKLARKYAHTVLHIDDPVILTAHASFHGRTLATITATGQPKYQKNFAPLVPGFAYVPFNDIEAIKTAIAELDGGEKRRVAAILLEPLQGEGGVRPGDVSYFQAVRQICDDLGILLILDEVQVGMGRSGKLWGYENLGIEPDIFTSAKGLGGGIPIGATLCKSSCNIFQPGDHASTYGGNPFACGVALTVCQTLEQENLLVNAAQRGEQLRQGLQAIATQYPNLIAEVRGWGLINGLELSAETEMTSIEIVKVAMAAGLLLVPAGPKVVRFVPPLIVTASEVDEALATLGKAIAQLSA
>NC_019693.1|WP_156823926.1|5605909_5607523_+|sodium:proton-antiporter
MTNRAPFPHFLSQIESGTSVQSGRVEELAIVLIILLLVATFVAIFSRRFKVPYVTGLVLAGLAITEFLPGNIGLDSSLILNLFLPILVFEAAINTDISRLRSTIVPISLLAGPGLMVSFGVTGLLIKFGLGLDWIPALLVGVILAVTDTVSVIAVFKEVSVPSRLSTIVNGESLFNDGVALVIFTLLVNVQIMGSFSFVNGLQQLFIVILGGTIIGVMVGYLSSGLLARYDDGLTSILLSVAVALGTFQLGQLLGVSGVVGVVVAGLLVGNIGIKQTASASNRIALYSFWEYAGFGVNTFIFLLIGLEINPLTLWNTLPAVLLAILAYQVGRLLSVYPLLTLLQWVDRPIPIRWKHVLFLGNIKGSLSMAMALTLPATLEGRSQLIALLFGTVLLSLVGQGLSLPWLVKRLNIQEISAFRQKIQELQAQLMAAKAAQEELNNLLKAGVLPKSIYEEMRASYQVKIAGAEKQLRDIYNIRPEDENGGDRGKLDAVWRQVLLAEKSALNDALRKQILSEEIVQKQVNYLNQQLLKLEDD

Crispr_ID: NC_019693_61

• CRISPR_ID: NC_019693_61
• CRISPR_location: 5642565-5642680
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_61

Consensus_repeat	Method
CACCAAAGCTGATGCCACTACAGAAGATGGTACCG	CRISPRCasFinder

spacers of NC_019693_61

>61.1|5642600|46|NC_019693|CRISPRCasFinder
AAGCTGATGCGGACCTGATCGCCACGACTTCTGTTGTGGAAGAGGA

CRISPR arrays and Neighbor proteins around NC_019693_61

CRISPR arrays

The CRISPR arrays of NC_019693_61

>merge|NC_019693|61|5642565-5642680|CRISPRCasFinder
CACCAAAGCTGATGCCACTACAGAAGATGGTACCGAAGCTGATGCGGACCTGATCGCCACGACTTCTGTTGTGGAAGAGGACACCAAAGCTGATGCCACTACAGAAGATGGCACCG

>NC_019693|61|59|5642565-5642680|CRISPRCasFinder
CACCAAAGCTGATGCCACTACAGAAGATGGTACCG	AAGCTGATGCGGACCTGATCGCCACGACTTCTGTTGTGGAAGAGGA
CACCAAAGCTGATGCCACTACAGAAGATGGCACCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015150530.1|5626173_5626572_+|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|273648
NC_019693.1|WP_015150548.1|5656340_5656982_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379188
NC_019693.1|WP_015150534.1|5634173_5634986_-|DUF1822-family-protein	unknown	unknown	gnl|CDD|370155
NC_019693.1|WP_015150531.1|5626802_5628455_+|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl|CDD|223733
NC_019693.1|WP_015150529.1|5624984_5626034_+|mannose-1-phosphate-guanylyltransferase	unknown	unknown	gnl|CDD|223906
NC_019693.1|WP_015150543.1|5651245_5652235_-|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
NC_019693.1|WP_015150533.1|5630073_5633763_-|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NC_019693.1|WP_015150541.1|5649038_5650421_+|low-complexity-protein	unknown	unknown	gnl|CDD|224276
NC_019693.1|WP_015150542.1|5650516_5651080_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150540.1|5647473_5648796_+|protein-kinase	unknown	unknown	gnl|CDD|319862
NC_019693.1|WP_015150547.1|5655623_5656148_+|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl|CDD|223854
NC_019693.1|WP_015150536.1|5635901_5636456_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150537.1|5637182_5637572_+|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl|CDD|234918
NC_019693.1|WP_044197707.1|5637804_5640663_+|aminomethyl-transferring-glycine-dehydrogenase	unknown	unknown	gnl|CDD|235432
NC_019693.1|WP_015150546.1|5655181_5655442_+|hypothetical-protein	unknown	unknown	gnl|CDD|319253
NC_019693.1|WP_015150532.1|5628755_5629115_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150544.1|5652596_5652896_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	unknown	unknown	gnl|CDD|177056
NC_019693.1|WP_015150535.1|5634985_5635861_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156824089.1|5653151_5654777_-|SpoIID/LytB-domain-containing-protein	unknown	unknown	gnl|CDD|225259
NC_019693.1|WP_015150549.1|5656990_5657803_-|DUF1350-domain-containing-protein	unknown	unknown	gnl|CDD|115718

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015150530.1|5626173_5626572_+|cupin-domain-containing-protein	gnl|CDD|273648	TIGR01479, Mannose-1-phosphate_guanylyltransferase, mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. This enzyme is known to be bifunctional, as both mannose-6-phosphate isomerase (EC 5.3.1.8) (PMI) and mannose-1-phosphate guanylyltransferase (EC 2.7.7.22) in Pseudomonas aeruginosa, Xanthomonas campestris, and Gluconacetobacter xylinus. The literature on the enzyme from E. coli attributes mannose-6-phosphate isomerase activity to an adjacent gene, but the present sequence has not been shown to lack the activity. The PMI domain is C-terminal. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	7.34752e-50
NC_019693.1|WP_015150541.1|5649038_5650421_+|low-complexity-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.42917e-21
NC_019693.1|WP_015150548.1|5656340_5656982_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.57759e-06
NC_019693.1|WP_015150534.1|5634173_5634986_-|DUF1822-family-protein	gnl|CDD|370155	pfam08852, DUF1822, Protein of unknown function (DUF1822). This family of proteins are functionally uncharacterized.	2.65033e-23
NC_019693.1|WP_015150531.1|5626802_5628455_+|AarF/ABC1/UbiB-kinase-family-protein	gnl|CDD|223733	COG0661, AarF, Predicted unusual protein kinase [General function prediction only].	2.18892e-148
NC_019693.1|WP_015150529.1|5624984_5626034_+|mannose-1-phosphate-guanylyltransferase	gnl|CDD|223906	COG0836, {ManC}, Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane].	2.50521e-148
NC_019693.1|WP_015150544.1|5652596_5652896_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	gnl|CDD|177056	CHL00134, petF, ferredoxin; Validated.	1.24116e-59
NC_019693.1|WP_015150533.1|5630073_5633763_-|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	9.77484e-33
NC_019693.1|WP_015150543.1|5651245_5652235_-|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.5555e-39
NC_019693.1|WP_015150540.1|5647473_5648796_+|protein-kinase	gnl|CDD|319862	cd16383, GUN4, porphyrin-binding protein domain GUN4. GUN4 is a porphyrin-binding protein involved in chlorophyll biosynthesis regulation and intracellular signaling, found in aerobic photosynthetic organisms. It has been implicated in retrograde signalling between the chloroplast and nucleus. GUN4 can bind protoporphyrin IX (PIX) and magnesium protoporphyrin IX (MgPIX), substrate and product of the Mg-chelatase, as well as heme and cobalt protoporphyrin IX (CoPIX). It may play a role in protecting plants from reactive oxygen species (ROS)-mediated damage.	2.53714e-68
NC_019693.1|WP_015150547.1|5655623_5656148_+|DNA-starvation/stationary-phase-protection-protein	gnl|CDD|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	3.32075e-69
NC_019693.1|WP_015150537.1|5637182_5637572_+|glycine-cleavage-system-protein-GcvH	gnl|CDD|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	1.56895e-64
NC_019693.1|WP_044197707.1|5637804_5640663_+|aminomethyl-transferring-glycine-dehydrogenase	gnl|CDD|235432	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase.	0
NC_019693.1|WP_015150546.1|5655181_5655442_+|hypothetical-protein	gnl|CDD|319253	cd16395, Srx, Sulfiredoxin reactivates peroxiredoxins after oxidative inactivation. Sulfiredoxin reduces and thereby re-activates 2-cys peroxiredoxins. Peroxiredoxins act as molecular switches, inactivating in response to hyperoxidation from hydrogen peroxide and other free radicals. Sulfiredoxin reactivates Prx-SO(2)(-) via ATP-Mg(2+)-dependent reduction. Arabidopsis sulfiredoxin has been described as a dual function enzyme, having nuclease activity in addition to the sulfiredoxin activity. This protein is similar to ParB N-terminal-like domain of bacterial and plasmid parABS partitioning systems.	1.42973e-39
NC_019693.1|WP_156824089.1|5653151_5654777_-|SpoIID/LytB-domain-containing-protein	gnl|CDD|225259	COG2385, SpoIID, Sporulation protein and related proteins [Cell division and chromosome partitioning].	5.87386e-92
NC_019693.1|WP_015150549.1|5656990_5657803_-|DUF1350-domain-containing-protein	gnl|CDD|115718	pfam07082, DUF1350, Protein of unknown function (DUF1350). This family consists of several hypothetical proteins from both cyanobacteria and plants. Members of this family are typically around 250 residues in length. The function of this family is unknown but the species distribution indicates that the family may be involved in photosynthesis.	1.37231e-127

Protein sequences

>NC_019693.1|WP_044197707.1|5637804_5640663_+|aminomethyl-transferring-glycine-dehydrogenase
MTQDAFVHRHNGPSSDEIKQMLEELGFSSLDSLIESTIPSRIRRHIPLNLPQPLSETAALTQLKQIASQNQLFRSFIGMGYHDCITPPVIQRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTMIVDLTGLEIANASLLDEATAAAEAMTLSYGFCKTKATAYFVSEDCHPQTIEVVQTRARPLGIEVIVGNPRQFTFDRPVFGVLLQYPATDGAVYDYRELVEKAHTAGAVVTVAADILSLALLTPPGEFGADIAVGSTQRFGVPLGYGGPHAAYFATRDEYKRQIPGRIVGVSKDVNGDRALRLALQTREQHIRREKATSNICTAQVLLAVIASMYAVYHGPGGIKRIAKTVHHLTVILAAGLTRLGYNLGSEPFFDTLRVELGTKSQSELLAAAANHQINLRVLDETTLSISLDETTTLEDLQNLWAIFASGEPLPFTVEQLATEVNSSFDSTFARTSSYLTHPVFNRYHSETELLRYLHRLESKDLSLTTSMIPLGSCTMKLNATAEMIPVTWPEFGKIHPFAPVAQTQGYQQLFQQLEAGLAEITGFAGISLQPNAGSQGEYAGLLVIRQYHEHRGESHRNVCLIPTSAHGTNPASAVMCGMKVVPIACDENGNINVEDLKAKAQKHSENLAALMVTYPSTHGVFEVGIKDLCQVIHDCGGQVYMDGANMNAQVGLCRPGDFGADVCHLNLHKTFCIPHGGGGPGMGPIGVMPHLVPFLPGHSVVKVGGDEAIGAVSAAPWGSASILPISWMYMAMMGAAGLTAATQVAILNANYIAKRLEPYYPVLYKGKTGLVAHECILDLRSLKKSAGIEVEDIAKRLMDYGFHAPTVSWPVAGTIMVEPTESESKEELDRFCEAMIAIREEIRAIEAGTMDGENNLLKNAPHPATVAIASEWNRPYSREQAVFPAPWTREHKFWPSVGRIDNAYGDRNLVCACLPMEVYSQE
>NC_019693.1|WP_015150537.1|5637182_5637572_+|glycine-cleavage-system-protein-GcvH
MNLEYPEDLKYLDSHEYVRLDGEIATIGISAFALDQLGDIVFVELPDISEALEKGSTFGTIESVKAVEDLYAPISGTIVERNNEVIEAPELIGDDPYGEGWLLKVRVNDPDELEEAMSANEYRAQVEGE
>NC_019693.1|WP_015150536.1|5635901_5636456_-|hypothetical-protein
MATTLAQIAQYLDNRGWGYDLQEANSQIITGYQAQNVEQFLIVIQLQEEGEYLSVFVPELLQVKDHVYKGVVFQTMLEIAWSVKFLRWEYDPRDGEIRASIGFALEDAALTDRQFNRVLDALIHLVDEVAMPRLQAVLATGNDPGAPEMAQDIAAALAQLLPDGSLEALQPAIASHLQSRSEGE
>NC_019693.1|WP_015150535.1|5634985_5635861_-|hypothetical-protein
MSDFRTDSFESGMNGDRVNLPLLESRVIPENNGCTRRQGDRKMDSIAALCHELNELVRQGCQFPPQHLQRRKIMDQIVRKIGQSRQLYLKRTAENSQDYPDALQQTWLYFSHNLYQTYDPDRPGSCLIPWLRTYLEKRLLEFNIGDCTRTTDPETGERKRRKIFYAQPVADSEGNLLNPLDLIAAQGDPQPLLNDTLDWVTSDPSGILQRVTMRDRQDITAQVVLKLLLPPDCLNQTEIAKHLHLPQPSSIQTFYKKSLRLLLEYWEFDDPQIQAILAPKKTSKKQPGGES
>NC_019693.1|WP_015150534.1|5634173_5634986_-|DUF1822-family-protein
MSTTQIREQPIDDFSITIPLTEEDRDIADIFAVTQPNPEAAERVRGNTLSVIAVAFYLDLHQIETDITSAQLWNRKQRQTQDIADLPLPGIGWIECRAFSPDQTEIRLPPHPDPQRIGYVGVELNPDTPETAKLLGFVAPSDSTTPLETLHREQLGSLDDFLDVLTRLELLGAILAARDDSPLPETLRQRAITELQRVYAASPDEPWEWAGLAEQRLFDDTLTRNSKDLMVTTNRETPTQSDSDKRRLQQRSFLESVLEEMDEQWRKLSE
>NC_019693.1|WP_015150533.1|5630073_5633763_-|CHAT-domain-containing-protein
MTTTLEQITQFLDAQNWTYQTEPENHRIHLTIEGLPVILNLEENGELLRCFIPQLLTISAEHPYAETAMATLLRLGWELKLVRWQRNPSDGEVRVTTEIPLEDATLTPRQLRSTLTRLVVLGKRAKQRLETVLTTGDDPGMPDSSGPSVGHEVLEFLEALMEAEVTGGEESVYPLLSAHLSLLDQGFVTAITTLAHAIYAKGDLEQSEMIAALIENLSISIQEFPGGNFLENQNIAIAGYQLVLEARPRERVPDKYAQTLNNLGNAYCTRAELGDNSAENLSEAIAAYQEAEKIRRNLKLFKDLADTLNNLGNAYLTRAQLGDNSAENLSEAIATYQEAEKIRRNLKLFKDLAGTLNNLGNAYCTRAELGDNSAENLKWAISAYKESEKIRRELNLSKDLADTLNNLGNAYRNRAELGDNSTENLSEAIAAYQEAEKIHRELNLFKDWATTLNNLGNAYLTRAELGKNSAENLNWAISAYQEAEEIRRELNLFKDLAETLNNLGIVYLIRAELEDNSAENLNWAIAAYQEAEEIYCELNLFKDLADTLTGLGNAYLTRAELEDNSAENLSWAIAVYQEAEEIYRELNLFKDLANTLTGLGNAYLIRAELGENSAENLNWAIAAYQEALQYLPPKLQPANCLKTAKNLVRLAMGRQDWNLALDASHKAIEALEQSRAWAKTEALRQDIIHQGIRVYENAIQAAVNCDRLDLALQIVERVRSKRLVDLMATADLYADGQVPESVRQKLDHLQQLQQQIDAQRFLLERPSDSSTGDKSFFAASSPRAATEALSQEILALETAKQQVLDALSQEDNVIAKLQQVVPLELAQMQELLDKPTVALLSFYTTDDDTHIFILRGDGSLHRHTCAGQGLNTLQGWLVETWVTPYAWIGAANEAERQIRKEKWQDQMPQVLQELSQRLEWDKLIQDHLENIEELILIPHLYLHQIPFVALPTNSGEYFGDRFRLRYAPSCQVLSFCHSRPSVEDTTYGTVENATDDLPFTRVEGDMVAQLFQIPPERRLRGRQAATGEAYRGLLEVCTHLLSSHHAQTRFDNPLESALYLGNGTITVSQLLSPGWRFPELSDIFLCCCETGLNLPQNLADELITLGTGFLCAGARAVLSSQWSVGDISTAVLSGLYHEARQKGCDRASALQQAQRQLRELTKDDFVKGQKKLLYQLQKQAEKEGNLQASEDYYTGIRTLVDDFVKKKDPTDRLFNQPVHWAAFRCEGLG
>NC_019693.1|WP_015150532.1|5628755_5629115_-|hypothetical-protein
MTIEPLKLQDTLEDLEIEDLFSNITADLVEYKAHEPFINRLFSHQAGTWLEIADLVQDLPDIKAQLQEINERYDGNFQVSWLEGPDGIDSTGYCLMVFLADTLQWTNVAIYNKARFFRN
>NC_019693.1|WP_015150531.1|5626802_5628455_+|AarF/ABC1/UbiB-kinase-family-protein
MWSNLTQSSARQREIFEVVLRNGWDYMRRLLTGGKTDEPKLPPPAVLRNIFVDLGPVYVKVGQLLSTRPDLLPQEYIDELTALQAEVPPVPWEDVEVTIRQQLRQPIEDVFATLNTEPVAAGSIAQTHRATLKNGQEVAVKVQRPGLEKIIEQDITLLTGLAELVSIAEFGDSYDLVALAEEFGTALRGELNFTEEGANGDKLRRNLAKSRWFDPTKVAIPEIYWNLTTEKLLVMEWVEGEPILLAKYDGMPGIDRITQRKAIANLLTRVFFQQICLDGFFHADPHPGNLFYLRDGRVALIDCGMVGRMDPRTQQLLIEMLLAMVNLDAQRCSQLAIDMAGSTSKTVNVSNLESDYDRLLRRYYNMSLSELSFSQMFYEVLEVSRNNRLRMPANMGLCAKAIANLEGIARNLDPDYNFAEQIKPLMTDLFGRQLIGEAPLQGLLRTALDIKNLSLQSPRQFEVLLDRVTSESLIWNVAMKDVEALRRTLDSAANRLSFSILVGSLIMGAAVVSSQAQLSNVYYLSDILFAAASLIGLWLVISILRSGRLR
>NC_019693.1|WP_015150530.1|5626173_5626572_+|cupin-domain-containing-protein
MTETKNPTELESVNASDSGLHTEERFWGTATVLETGERYRISRVEVKPGHRMKTQIHYHRSEHWIVVSGTAKIVCGEKESLLIQNQSSYVPICTPHRLENPGVIPLVLIEVQNGEFLGDEDIIRLEEDDKEG
>NC_019693.1|WP_015150529.1|5624984_5626034_+|mannose-1-phosphate-guanylyltransferase
MIPVILAGGKGERFWPLSRRSRPKQFLSLDGSGISLLQATANRLLAVAGGWDGLWVVTNAQIADGIREQLPQLPEKNILIEPQGRDTAPAVAWAAIEIERREGPEAVVGFFPADHWIGDEDAYGKTLAAASQLATDTPAIVTLGITPTEPSTGYGYIEQGEVVAPYQGLNAYRVSRFTEKPDRPKAEEFIATGRYTWNSGMFIFRAGVVIEELKTHAPEIFEPLAQKGVAAYAELPKKSIDYALMEKTQLAYVIPAAFGWDDLGDWNALERLLKGDQTNVELANHIGLDTQGAILYASSDDERIVTIGLEDIVIVRDRNVTLIVKKDRTQDIKQVLKQLENDPRFSPEL
>NC_019693.1|WP_015150540.1|5647473_5648796_+|protein-kinase
MAWQPGEQLLNGKYTIESKLGKGGFGITYLARDDRNRPFAIKTLGRKARFTQELVKYKKEFLKEADCLLRCIHPSIVRLEEVIDTDSLCCIVLEYIDGTPLARLVKQKGRLSEREALFYTYQIADALRLVHQQGFLHRDVKPMNIVLRQERSDAVLIDFGLAQEFFQDQVEIHPKQGSRGFAPLEQYDLRALRGAYTDVYGLSATLYSLLTAKVPPSASSRDRSWVKTQTDPLLPPKTLNQSVSDRVNTAILKGMALTPEHRPQSIDAWLELLSDEPSDSSPQPPEMTSAIPEITNSISAVGMDYTTLETLLAAGQWQEADRETDALMLRVAGREAEGRLNIEDVKHFPCRDLRTLDRLWTEHSKGHFGLSIQRQIWSESEIEENYESFSDRLGWRRDNEWVSYGDLTFDITAPVGHLPSWGRRGRLWSFLATRLKKCSL
>NC_019693.1|WP_015150541.1|5649038_5650421_+|low-complexity-protein
MNPEPTPNSSDPNSRDNSSSGNPSHRGNNPVNPERPQGLIANATPERDRTPRNNGVILEPLTPSEALTELDEYQQNLGRKQPSQITLPPLEDNSSSSPGGVLVLAAIAIMVFGLAIDNILLGFAGAVATFAISLRIIWPNWSRIWLQLVPDPWRAVVIAFVGLLTGIIGLLMLSGSNQQPGSRNIQINWEAIGAVGEIVGALGQILIAIIAVYVAWRQYVISKELTIQQNRITQQQTIDTYFQGVSDLALNEEGLLEDWPQERAIAEGRTAAILASVDSEGKAKIIRFLSQSRLLTPLMRDRHLGRPILDGDGGYAEDRIDGVRVIALGVMLAGADLSSTDLRWTELSEANLVRADLQNCDLVKANLSRAILYEANLSGADLNSTRFFYGPVETASPRSRTKRPNYQTGEHTGAVVENANFSKVERLSETQRYYICAWGGSKTRATVPGGCDDIPNLLGR
>NC_019693.1|WP_015150542.1|5650516_5651080_-|hypothetical-protein
MAASLQQIADYLDNRAWQYEIDPEHHRIITGVQAENLESFPIVIQLDEDGEFFKLFAPKVLSGISNHPFKELILQTMLCISWETKMLQWEYDPTDGEIRAIIEFPLEDSLLTERQFNRCLSGLIQIVDDIAMPRLKTVMETGKDPGDEDIGERLLLTLQEEAPGLLDLLEKAMQARKKRGILPSDYF
>NC_019693.1|WP_015150543.1|5651245_5652235_-|Gfo/Idh/MocA-family-oxidoreductase
MRVGLVGTGFVAKLRGQTLQEDERSRLVAVAGHTPEKTEEFAQIHRTTAMNSWQDLIARGDLDLVIICNINRDRGAIIRAALLADCHVVVEYPLCLDPAEAEDLLALATARKRLLHVEHIELLGGVHQALKQSWAAVGDVAYARYSTLNPQRFVGRKWSYHRELLGFPLTAALSRLHRLTDVLGKVATVSCQSRFWEVPTEPEYFRACLCSAQLRFTNGAIAEVLYGKGEIFWARERKLEVHGSQGTLIFDRDQGQLVRDGDITPLEIGTRRGLFAQDTQMVLDHLTQGTPLYIDPRASLYTLKVADAARLASETGKTIALEEETEPHF
>NC_019693.1|WP_015150544.1|5652596_5652896_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein
MATFKVTLINEAEGLNQTIDVEDDTYILDAAEEQGLDLPYSCRAGACSTCAGKITSGTVDQSDQSFLDDEQIEAGYVLTCVAYPSSDCTIMTHQEEELY
>NC_019693.1|WP_156824089.1|5653151_5654777_-|SpoIID/LytB-domain-containing-protein
MGRQWLGRISGVVFTVLCFWSVPGEVVRANQVQNRELEIGVVQRFGSKPTDKLILKAPEGDRLYVRFEGGDGTPQTQEMSEMQLEIVMKPLAEPMLEERLVLSTHRSFENAEQNADEWRNKGIAVEIAHPGRWQVWAKREVYGTPLLRRFLLQNLQAEGYEAAFLDTAIVQQSPQPSWVYEGFRYNRDRLEIWAGSDRIQVSREKEDRNPTLYPGNLRIQPNAYGSFTLVNEVPIEEYLRGVVPHEIGADAPYPAVEAQAIIARTYVLRNLRRFAIDNYELCANTECQVYKGVGETWERSDLAIAATAGKVLTYNNELIDALYSSTTGGITAPFQDMWDGADRPYLRAVLDSVGNVWDLSRYSLDNEQNFRRFITLDKGFNEEGWDVFRWREVSSLAQMNKNLKDYLQEKQHPQANFQTIKAVDVVERSNAGRAIAVNVTTDRGSVRLVKDEILRAFWAPLSTFFYLERMYGEDKSFKGYVFVGGGFGHGVGLSQSGSHRLAKLGWTSDRILKFYYPGTEIQPISEDIIFWRDPLVTGDRG
>NC_019693.1|WP_015150546.1|5655181_5655442_+|hypothetical-protein
MRVEEIPIAKIRRPLPRQNDLQKVETLMASIQEIGLLEPIDVLEVEGEYYGFSGCHRYEACQRLGHKTIRCNVRRAPRSVLKMHLA
>NC_019693.1|WP_015150547.1|5655623_5656148_+|DNA-starvation/stationary-phase-protection-protein
MAKDKDKEKDKEKDKDKGSKINTGINVEDRQQIAEGLSRVLADTYTLYLKTHNFHWNVTGPMFQTLHLMFEEQYNELALAVDAIAERIRALGYPAPATYSEFSKLSSIEETLGVPKAKEMIQLLVEGQEAVVRTARSVFPTADGANDEPTADLLTQRMHIHEKTAWMLRSLLEE
>NC_019693.1|WP_015150548.1|5656340_5656982_+|helix-turn-helix-domain-containing-protein
MSDTPDASQQLQGLMQRVGIPSFRSLARQAGVSHWQVRQLRQGKALQMRVEPLLVLANVLQVTLSELLVRCAGVEEAEPLEQSSTVQAEYDRLQVQMQQQRETLLQEFQLTSLDILESWLRNWPTAAYAATQNPDLPAVRLLPLLHPVERLLQEWGVEAIAPVGSDIPYNPQQHQLREGMAEPGELVRVRSTGYRQGDKLLYRAEVSPKKEQE
>NC_019693.1|WP_015150549.1|5656990_5657803_-|DUF1350-domain-containing-protein
MNWQEISGNWVHIPPRTRGIVHFLGGAFLAAAPQVTYRWLLEQLSLQGYAIIATPFVSNFDHGAIAANILERFEWCVEQLRLSGKLPKRYLPIYGIGHSMGCKLHLLIGSLFEVERAGNILISYNNYPARRSIPFLELMEQLPTAWGSKLPTAFSVEFTPSPEETNQIIARNYQIKRNLIVKFKDDTLDQTLLLFPVMQKRFPDLVSMLTIPGNHLTPLSQDPGWKSGTEFSPLDAIAQWVRLEMYREPVRLKDEILRWLNPIPSMRPLN

Crispr_ID: NC_019693_62

• CRISPR_ID: NC_019693_62
• CRISPR_location: 5697879-5698036
• CRISPR_type: TypeV
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: RT

Consensus repeat of NC_019693_62

Consensus_repeat	Method
TCTTGTAGGGGCGTATTGCATAC	CRISPRCasFinder

spacers of NC_019693_62

>62.1|5697902|50|NC_019693|CRISPRCasFinder
GCCCTCTTTATCCTCAATATCCGTCAATGGAATCGGGCCTCATCCTTGTT
>62.2|5697975|39|NC_019693|CRISPRCasFinder
ATCAGAGGGCGTATGCAATACGCCCCTACAAATACACCT

CRISPR arrays and Neighbor proteins around NC_019693_62

CRISPR arrays

The CRISPR arrays of NC_019693_62

>merge|NC_019693|62|5697879-5698036|CRISPRCasFinder
TCTTGTAGGGGCGTATTGCATACGCCCTCTTTATCCTCAATATCCGTCAATGGAATCGGGCCTCATCCTTGTTTCTTGTAGGGGCGTATTGCATACATCAGAGGGCGTATGCAATACGCCCCTACAAATACACCTTCTTGTAGGGGCGTATTGCATAC

>NC_019693|62|60|5697879-5698036|CRISPRCasFinder
TCTTGTAGGGGCGTATTGCATAC	GCCCTCTTTATCCTCAATATCCGTCAATGGAATCGGGCCTCATCCTTGTT
TCTTGTAGGGGCGTATTGCATAC	ATCAGAGGGCGTATGCAATACGCCCCTACAAATACACCT
TCTTGTAGGGGCGTATTGCATAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_044195695.1|5708591_5709224_+|hypothetical-protein	unknown	unknown	gnl|CDD|234750
NC_019693.1|WP_015150584.1|5706442_5706703_+|DUF3148-domain-containing-protein	unknown	unknown	gnl|CDD|371482
NC_019693.1|WP_015150588.1|5709397_5710852_+|DUF2157-domain-containing-protein	unknown	unknown	gnl|CDD|227209
NC_019693.1|WP_044195689.1|5690219_5690921_-|transcriptional-regulator	unknown	unknown	gnl|CDD|225222
NC_019693.1|WP_015150569.1|5684209_5685280_+|type-2-isopentenyl-diphosphate-Delta-isomerase	unknown	unknown	gnl|CDD|235465
NC_019693.1|WP_015150574.1|5691345_5691732_-|KGK-domain-containing-protein	unknown	unknown	gnl|CDD|370166
NC_019693.1|WP_015150582.1|5702491_5703826_-|PAS-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_019693.1|WP_015150575.1|5691928_5692300_-|KGK-domain-containing-protein	unknown	unknown	gnl|CDD|370166
NC_019693.1|WP_044195692.1|5698242_5700471_-|Na-K-Cl-cotransporter	unknown	unknown	gnl|CDD|273347
NC_019693.1|WP_015150578.1|5697047_5697821_+|1-(5-phosphoribosyl)-5-[(5--phosphoribosylamino)methylideneamino]imidazole-4--carboxamide-isomerase	unknown	unknown	gnl|CDD|179108
NC_019693.1|WP_015150583.1|5704025_5705870_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|224271
NC_019693.1|WP_156824055.1|5685519_5687265_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209
NC_019693.1|WP_015150589.1|5711123_5711819_+|GDYXXLXY-domain-containing-protein	unknown	unknown	gnl|CDD|379571
NC_019693.1|WP_015150577.1|5695224_5696700_-|lysozyme-M1	unknown	unknown	gnl|CDD|119384
NC_019693.1|WP_015150573.1|5691072_5691318_-|HNH-endonuclease	unknown	unknown	gnl|CDD|372995
NC_019693.1|WP_015150586.1|5708130_5708679_+|pantetheine-phosphate-adenylyltransferase	unknown	unknown	gnl|CDD|234674
NC_019693.1|WP_015150571.1|5688119_5689949_+|signal-peptide-peptidase-SppA	unknown	unknown	gnl|CDD|273226
NC_019693.1|WP_015150576.1|5692416_5694867_-|dynamin-family-protein	unknown	unknown	gnl|CDD|223771
NC_019693.1|WP_015150585.1|5706699_5707599_+|YegS/Rv2252/BmrU-family-lipid-kinase	unknown	unknown	gnl|CDD|234850
NC_019693.1|WP_044197719.1|5700909_5702232_+|oxidoreductase	unknown	unknown	gnl|CDD|226582

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_156824055.1|5685519_5687265_-|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	2.5e-47	155.9	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_044195695.1|5708591_5709224_+|hypothetical-protein	gnl|CDD|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	0.00020552
NC_019693.1|WP_015150584.1|5706442_5706703_+|DUF3148-domain-containing-protein	gnl|CDD|371482	pfam11347, DUF3148, Protein of unknown function (DUF3148). This family of proteins has no known function.	2.4911e-37
NC_019693.1|WP_015150588.1|5709397_5710852_+|DUF2157-domain-containing-protein	gnl|CDD|227209	COG4872, COG4872, Predicted membrane protein [Function unknown].	2.99163e-40
NC_019693.1|WP_044195689.1|5690219_5690921_-|transcriptional-regulator	gnl|CDD|225222	COG2345, COG2345, Predicted transcriptional regulator [Transcription].	2.92613e-51
NC_019693.1|WP_015150569.1|5684209_5685280_+|type-2-isopentenyl-diphosphate-Delta-isomerase	gnl|CDD|235465	PRK05437, PRK05437, isopentenyl pyrophosphate isomerase; Provisional.	0
NC_019693.1|WP_015150574.1|5691345_5691732_-|KGK-domain-containing-protein	gnl|CDD|370166	pfam08872, KGK, KGK domain. This presumed domain is found in one or two copies in cyanobacterial proteins. It is named after a short sequence motif.	2.4257e-16
NC_019693.1|WP_015150582.1|5702491_5703826_-|PAS-domain-containing-sensor-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.89343e-34
NC_019693.1|WP_015150575.1|5691928_5692300_-|KGK-domain-containing-protein	gnl|CDD|370166	pfam08872, KGK, KGK domain. This presumed domain is found in one or two copies in cyanobacterial proteins. It is named after a short sequence motif.	2.17258e-27
NC_019693.1|WP_044195692.1|5698242_5700471_-|Na-K-Cl-cotransporter	gnl|CDD|273347	TIGR00930, Solute_carrier_family_12_member_1, K-Cl cotransporter. [Transport and binding proteins, Other].	3.81829e-142
NC_019693.1|WP_015150578.1|5697047_5697821_+|1-(5-phosphoribosyl)-5-[(5--phosphoribosylamino)methylideneamino]imidazole-4--carboxamide-isomerase	gnl|CDD|179108	PRK00748, PRK00748, 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Validated.	6.38641e-136
NC_019693.1|WP_015150583.1|5704025_5705870_-|PAS-domain-S-box-protein	gnl|CDD|224271	COG1352, CheR, Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms].	8.09992e-79
NC_019693.1|WP_156824055.1|5685519_5687265_-|group-II-intron-reverse-transcriptase/maturase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	2.07589e-125
NC_019693.1|WP_015150589.1|5711123_5711819_+|GDYXXLXY-domain-containing-protein	gnl|CDD|379571	pfam14345, GDYXXLXY, GDYXXLXY protein. This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 171 and 199 amino acids in length. It contains a conserved GDYXXLXY motif.	2.89723e-24
NC_019693.1|WP_015150577.1|5695224_5696700_-|lysozyme-M1	gnl|CDD|119384	cd06524, GH25_YegX-like, YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins.	7.63813e-71
NC_019693.1|WP_015150573.1|5691072_5691318_-|HNH-endonuclease	gnl|CDD|372995	pfam14279, HNH_5, HNH endonuclease. This domain is related to other HNH domain families such as pfam01844. Suggesting that these proteins have a nucleic acid cleaving function.	1.32903e-22
NC_019693.1|WP_015150586.1|5708130_5708679_+|pantetheine-phosphate-adenylyltransferase	gnl|CDD|234674	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional.	1.06114e-96
NC_019693.1|WP_015150571.1|5688119_5689949_+|signal-peptide-peptidase-SppA	gnl|CDD|273226	TIGR00705, Protease_4, signal peptide peptidase SppA, 67K type. This model represents the signal peptide peptidase A (SppA, protease IV) as found in E. coli, Treponema pallidum, Mycobacterium leprae, and several other species, in which it has a molecular mass around 67 kDa and a duplication such that the N-terminal half shares extensive homology with the C-terminal half. This enzyme was shown in E. coli to form homotetramers. E. coli SohB, which is most closely homologous to the C-terminal duplication of SppA, is predicted to perform a similar function of small peptide degradation, but in the periplasm. Many prokaryotes have a single SppA/SohB homolog that may perform the function of either or both. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	6.96302e-158
NC_019693.1|WP_015150576.1|5692416_5694867_-|dynamin-family-protein	gnl|CDD|223771	COG0699, COG0699, Predicted GTPases (dynamin-related) [General function prediction only].	2.27865e-26
NC_019693.1|WP_015150585.1|5706699_5707599_+|YegS/Rv2252/BmrU-family-lipid-kinase	gnl|CDD|234850	PRK00861, PRK00861, putative lipid kinase; Reviewed.	5.96196e-152
NC_019693.1|WP_044197719.1|5700909_5702232_+|oxidoreductase	gnl|CDD|226582	COG4097, COG4097, Predicted ferric reductase [Inorganic ion transport and metabolism].	1.43303e-125

Protein sequences

>NC_019693.1|WP_015150578.1|5697047_5697821_+|1-(5-phosphoribosyl)-5-[(5--phosphoribosylamino)methylideneamino]imidazole-4--carboxamide-isomerase
MEVIPAIDLLEGRCVRLYQGDYDRSDVFNEDPVAVAKQWVDEGATRLHLVDLDGAKAGEPRNLKTIEAIARAVSVPIQVGGGLREYASVANLLSLGIDRAILGTVAVEKPELVQQLAQEFPGHIVVGIDARDGKVATRGWLETSEVLATVLAQQMVELGVAAIIYTDIHRDGTLAGPNIGALRELAGAVDIPIVASGGVSSLTDLLSLLSLEPLGVNSVIVGRALYTGDVSLKEAIQAIGPGRIQDVPPDFGSSTFA
>NC_019693.1|WP_015150577.1|5695224_5696700_-|lysozyme-M1
MCAKGIDVSDWQHPVNWNSVVRDGMGFAFTKATEGATFVADSYRSNWAAMKSVGLPRGAYHFYRAKQDPRAQADVFLRTVKLEANDLPPVLDIESTDGVGASSIIRDITTWIEIVEKETKRRPIIYTYPSFWERIGNPKIFTDYPLWIAHYQTNNPWVPGGWDGWTFWQYTETGKVSGINGGVDVNWFNVCRQGGKGSHVKYIQMCLRDKGFNPGSIDGVFGATMHSTVMAFQRAMNVTVDGIVGIQTWTALVSAIQPPTQVQPTPPPVNLPTPTPIPQPILPPTPAPPWPPIQSGPTPVIRLIDVCRFYQGFSHQNQALNWLQGQVSQANLLEFARRWRGHASASSPINFVDVAKFYQGLPIQDQAIHWLQGQVSSGILNEFARWWRSGTQQVATQSTSISLVDVCNYYQSLTNQKQALQWLQTQIPSSTLSEFSRQWRKLASVPVTANISLVDVCQFYQGLTHQKEAVEWLQRQLHSSVLDEFTRKWRG
>NC_019693.1|WP_015150576.1|5692416_5694867_-|dynamin-family-protein
MTQLLPQCQQLQNQVDRILELLHQEPALRQQDITAVQSSLKKAVAPKFEIVFAGAFSAGKSMLINALLERELLYSAEGHATGTECYIEYAEPDQGRVVLTFLSGLEIKDQVTALCERLDIKAAINIDEPEVLKLLRQIGEAKLTKEGGESKSQLAKQAKALILLLDGFAENSSRIHPVNNNTFSMEQFNFSNLKEAASYARRGSNSSVLKRIEYYCYHPLLKDGNVLIDLPGIDAPVKRDAELTYRKIEDPETSAVVCVLKPASEGDMTTEETELLEKMRSNPGIRDRVFYVFNRIDETWYNSQLRQRLDDLIVTQFRDNNNRLYKTSGLLGFWGSQIKQTSERDRYGLDSLFAESVKNTGIQEDTPQFVNEFNRYCANSGKLSPSQFKIAVYSYETPNENYVRILNECGTSLLNQLISDSGIEEFRRSITNYLTNEKRPLLFKTLANDLQPVCLLLSRHYVQQYRDLESQPVNIEGLKLRRMEQLNNDLRLLGIALNKHITQEVNEVVTNQCLTFEEDFRKLKVRMVCRMDELLNTFSVEEAYRQATLTHPRNSTAPLLAILVEAFYYLSNELEEVLAEESERTIANYFAYLLERIRRQDYYRDLCRLVGGDAGLEQTVKNLEVQVQQAVRAAASTECDRFVRESPRFYDEGTFSIYQFRKVLQQTSQSFDCISMKDAEPAIRQLLKLDFEPKVKHTIQSTFRQTVNQTLKTHLLPLVKQQEEMILQQYNRARSHLEKTLEREAQEQLDSNQIQLQEVQDKIADYNEVVSGINSCLQAMLLDRYQLPLANSQEAIEVEFVEEEEDVELAEVVEMI
>NC_019693.1|WP_015150575.1|5691928_5692300_-|KGK-domain-containing-protein
MSNNFEPLDSEEVVSIDEVLKIVLNQPTFKVREFVGAFKEVIKKQSSIYIDRRTDEKAQWLDEGVNAQVLKYGAKNWQTGKVRIKFTLEFCPDEPEVQKTSTTNQPETSEPESPLDDIRRMQG
>NC_019693.1|WP_015150574.1|5691345_5691732_-|KGK-domain-containing-protein
MDNNFNILEYDEVVQIQEPLRILSGDPTLKTGEFIAALMLLLKQDPIHKWKTPPQNPEDGIKAQVLTYQAKGWQKGRIRIRFEFCPDDPDVEEIAVPNEPELPNEPELPSEPESPLDDIRRMIDEPTS
>NC_019693.1|WP_015150573.1|5691072_5691318_-|HNH-endonuclease
MSKTPRIRIPAAVRVYVLERDRHQCQSCGKTELETELNIDHIIPLAMGGSNDISNLQTLCRQCNQRKSADLDPRFQRRFDL
>NC_019693.1|WP_044195689.1|5690219_5690921_-|transcriptional-regulator
MTDEKQKAKEQILYLLKMQGATSATDLAEQLEVSPMAIRQHLQALRGEGLVDYSEQRRPIGRPVKLWQLTDRTLNLFPNTHADLMVEFLNSFESVLGEAELKKVLTERSRRQIQGYRVQFATLEGDGSPNSWQSRLDRQVQRFAEIRTKEGYMAEAIGQPDGSWLFIENHCPIDEAARTCRLLCRSELEVFKTLFGPTITIERVEHIMEGDRRCAYQITPNINSVERIKRTPP
>NC_019693.1|WP_015150571.1|5688119_5689949_+|signal-peptide-peptidase-SppA
MRDFFKYTFASILGTIVGLGVLGVLSLGGLLIVIGTIATSSKDAGPKVENNSMLVFDLSMNITDSQPTSTTAEALSRTLSDESDPSSMTLRRVVETINAATEDSRILGIYLHSSSSSSSNGYATLREVREALERFRDAGKTIIAYDQDWSEREYYLASVAEEILLHPLGIMEMNGLSSETTFLAGGLEKYGVGVQVTRVGKYKSAVEPFVLTESSPESRQQTEKLLSDIWSDFLTTVDRREKISAQQVQQVVNNRGMLMAPEAEQQGFVDRLAYFDEVVAQLKELTGKKEDDQTFRQVSLSGYATVSDDQRETRMRSAPQIALVYADGEIVSGEGGSTQVGGDRLAKQLRDLRRDEDVKAVVLRVNSPGGSATASEVIQREVQLMAESKPIVVSMGNVAASGGYWISSYGSKIFAQPNTVTGSIGVFGMLLNVQSLGNNQGITWDVVKTGPYADIETITRPKTAQEMALIQQMVDRIYERFLNLIVQSRNLPAQQVSEIAQGRVWSGQEAQQLGLVDEIGGLNDAILAAAELAELGDNWKVEDYPETRSFEQILIERLLGSRLKALVPTPEPDPLTAQLQQLYEEVSIVKNLNDPFHTYTRLPFTFEIR
>NC_019693.1|WP_156824055.1|5685519_5687265_-|group-II-intron-reverse-transcriptase/maturase
MNKVNTSLKTTETWNAIPWAKVQRKVFKLQKRIFQAAKSGQDAKARRLQKLLTSSYYARLLAVRKVTQDNQGKRTAGIDGVKSLKPEQRLELVKDLGEQFLAKALRRVWIPKPGRNEKRPLGIPTIRDRAEQALVKQALEPEWEARFEGTSYGFRPGRSAHDAIGRIYASINKGSYYVLDADITKCFDKINHEYLLSKLDCCSQHRRQIKQWLKAGVVDNGVFEETPSGTPQGGVISPLLANIALDGMARLIEELYPLIQGQKVKATLIRYADDFVVISPEIEIINQCKIALENWLKPVGLELKPEKTKICHTLREIEVNGEKVTPGFDFLGFTIRQYPVGKYKSGKTGGANSRLIGHKTHIKPSAKAIKAHSEALKGVIKNHKTAPQAALISRLNPIIRGWSNYYSGVVSAETFSQMDYNIWQQLRAWTVSRCGQANLEKLRKYFHKVTVKIGNGKERNEKWLFQAKDGLSLWKHSYTQITRHTLVKPEASPYDGNWSYWATRRGTSLEVPMRVAKLLKKHSGRCSRCGQYFAMEDLMEVDHIQPLSMGGKDEYRNLQLLHRHCHDKKTAEDMQNVKSYQ
>NC_019693.1|WP_015150569.1|5684209_5685280_+|type-2-isopentenyl-diphosphate-Delta-isomerase
MTNLNSGEETQSRKAEHIRVCLEDDVQFRVNGTGLDRYRFTHCCLPELDWQDIDLTTRFLGKSLGAPLLISSMTGGTEEAKRINSRLAVVAEEFQIAMGVGSQRVAVEKPEVGDTFAVRSLAPNILLFANLGAVQLNYGYGVDECRKAVDLLEADALILHLNPLQEAVQSRGDKNFRGLLDKIHELCNVLPVPVIAKEVGNGISAKMAQKLLEAGVGAVDVAGAGGTSWAKVEGERAKDSRQRRLGATFAEWGLPTADCITSIRAIAPSIPLIASGGLRNGLDVAKAIALGADLAGLAWPFLQAAAESEAAIQTLVEHLLAEISTVLFCTGNATLSELRDSDALQPQGSPATTGGG
>NC_019693.1|WP_044195692.1|5698242_5700471_-|Na-K-Cl-cotransporter
MPSFPFFRRPSPDPVNPPVSGGLGTFGGVYTPSILTILGVIMYLRFGWVVGNVGLIGTLIIVTLATSITFFTGLSISAIATDRVVRVGGAYYMISRSLGIETGGAVGIPLYFAQGLSVALYTIGFAESVVEAFPEFRTMQRAIALITTLAVALLAMKSARTAIRAQYFIMAAIVLSLVSFAFGSPVENTVIELWGAKPENSEPFWVVFAVFFPAVTGIMAGVGMSGDLRDPSRSIPVGTLAAVGTGYVIYMGLPILLAMRADASTLIANPLIMQEMAFWGPAILLGVWGATLSSALGSILGAPRVLQSLARDGILPSSMRILGNGRGPDDEPFIATCVTLGIAALAVAVGDLNTIAPVLTMFFLTTYMVLNVAAGIEGFLQSPSYRPTFRVHWAISLLGAIGCIAVMILIDAIATVVAGIIVLGIYIWLERRELESAWGDVRRGLWMEVVRTGIFNLSHEPDTKNWRPHILVLSGAPTRRWSLIELATAFTHNRGLITVSSVLPSGSRDTAQQTKLEATIRDYLEKRGVQALVRLITAPDPFVGAENLVEIYGLGPLVPNTILLGDSEEPSHRDRYCNMIANLHQAKRNLIIFRENADKGFGKRRRIDVWWGGLQANGGLMLILAYLVRSSSQWQNAQVYLKLVVPDRAAAESAETNIAALVKKLRIGAIPQVLIAEGQSFYDILHTSSQDTDLVFLGMATPRENYTDYYEQLQARAAGLPTTIFVLAAPDFAFEEVLTDNA
>NC_019693.1|WP_044197719.1|5700909_5702232_+|oxidoreductase
MRSPVAVAAFWIALYIAIALLPLLVLILHAPPEARDFWTEFSVALGFIGLAMIALQFALTARINRIESSYGIDIILQFHRYISLVAFTLIIIHPLILFINEPETLELLNVFQAPWRARFAVTGTVALIILVITSVWRQRLGIPYEEWRIAHGILAVCAVGFGIAHAVGVGYYLNFFWKVVLWSAVGFLALLLLIYVRLVKPWLMTRKLYLVEEVIPQRGDVWTLALRPRGHEGITFEPGQFAWITLEISPFRMREHPFSMSSSGDHAERLEFSIKALGDFTKTIKDVKPGTKAFLDGPYGTFTIDKYWDAAGFVLVAGGIGITPMMSMLVTACERKDDRPFLLIYGSKTWDDITFREELEALKDELDLKIVHVLREPPEDWDGETGYVDQELLEKYMPTHAGSRQYFICASPKMMDQVEAAFYELDVPVTHVHMEHFNLV
>NC_019693.1|WP_015150582.1|5702491_5703826_-|PAS-domain-containing-sensor-histidine-kinase
MENFTGQIEQARVRLEQMQQLAQEFSSPPPDLLEQVFGELSTALEELHVATEELQEQNQQLLSTREEVEIERERYQQLFEEAPDPYLVTNALGVIEEANAAAEQLFNWRRPFLIAKPLAVFVVLEERSAFRSQLEQLKTVGPLTEWEVQMLPRDRESFPAAISVSRVQDIQGNPMGFRWLIRNISDLKEAEKNRQDLAVQRELHLMKSRFIQILSNEFRTPLNTIHLCTQLLERYSDGVKQSKRSPIFEKIRGAIKQMTLLLDDILIFNEDKDSSYFKSFQVDLEKFCLKLIEEYKHLYNPGERSINFQATGDYPSVCINTKLFRHIFRNILSNCFKFTPESSEINVFLHCEKTQIVLTFRDQGLGILPEDLPHLFNIFYRGNNVGDIPGAGLGLAIVKKSVDLLGGEISLDSPAEGVGTNLIITLPTTPKSPSVNKRLPSPGK
>NC_019693.1|WP_015150583.1|5704025_5705870_-|PAS-domain-S-box-protein
MTANDQTSIFEALLEYLRQSRGFDFVGYKRSSLQRRVTKRMQVHQIDNFGDYLEYLKVHPEEFPALFNTILINVTSFFRDLTAWKYLASHTLPQIIKHKSPEEPLRFWTAGCASGEEAYTLAILLVETLGIEDCLRRVKIYATDVDEEALTQARNATYKAKDIESISEEFQQRYFRRVGDRFGLDGDLRRLVIFGRHDLIHDAPISRLDLLICRNTLMYFNAETQKRVLARFHFSLKDTGFVFLGKAEMLLTHSDLFSPLNLQHRIFQKVRKMDRRDRLLVLAQNRTEEAGRRSTLNIRLLEAAFNAIPLAQIIVDSDSNLVLANQLARSRFGIDRQDLGRRFQDLEISYRPVELRSQIERVYKEGNSILVSDVIRTWSDGSVQYLDIEISPLQQNTSAPLGVSITFNEVTRYHQLQEQLERSNQELETVNEELQSSNEELETTNEELQSSHEELETTNEELQSTNEELETMNEELQSSNEELQTINDDLGQKTIELNQCNVFLESIFASLQSAVIVVDRQFQIQTWNEAAQNLWGPKADEVQKQSLFNLDIGLPVERLRDPLYQCLSGTQPGQEILIDALNRQGGSIQCRLSFNPLKDGSKEPHGVILLIKEV
>NC_019693.1|WP_015150584.1|5706442_5706703_+|DUF3148-domain-containing-protein
MSKEFTLGDRVRVVALPAYLKTAEPIPMLRPPNAVSLGEEGTIFDRKPGGYWSVRFKKGAFLIESHYIEPIQESVETSQEGTTENE
>NC_019693.1|WP_015150585.1|5706699_5707599_+|YegS/Rv2252/BmrU-family-lipid-kinase
MSTRSACLIFNPCSGKGNPEAELKQIFSLLEPEIKLDIRYTKPDLEPSQLAHEAVARGVDLVIASGGDGTVSAVAEALITTEIPLGVIPRGTANAFAVALGIPTNIPDACQTILHGLIRAIDGATCNGKPCILLTGVGWEAETVEQADREAKNWFGAMAYLVAGIEKLWDMQSFQVELEMDGEISTLRAIAVTIANAAPPTSVLAQGPGGVIPDDGLLDVTILSTQTEMSTLGAVSSLMTGALRGVASQHNDVLYLRTNRIKVTTNPPQKVTVDGEIRGTTPIEMECVPLSLNVMVPEI
>NC_019693.1|WP_015150586.1|5708130_5708679_+|pantetheine-phosphate-adenylyltransferase
MIAIYPGSFDPITLGHLDIIERGCKLFDQVIVAVVLNPNKTPLFTVQERLEQIRLATPHLSNLEIDCFEGLTVNYARIRGASVLLRGLRVLSDFELELQMAHTNKTLATEIETVFLATSNEYSFLSSSVVKEVARFGGSIDHLVPQHVALDIYRCYAKTQPGLTQTTDRVSQKNLPSTSRDS
>NC_019693.1|WP_044195695.1|5708591_5709224_+|hypothetical-protein
MLRQNTARIDPDDRSSLPEESPEHEQGLLDIQRELNRLEEMILESPRIPFTGRTLVDEEQLLEQLDLLRLNLPATFEEVEEIIRHKDEIIVQAEQYAQEILEAAEQRAAQILDEMGIVRQAKLESDHLRQQVQIDCESAQEQTISEIERLRRQALDDLEEMRSRAISEAEAIEKGADDYADRVLYNLESQLSEMLRVVRNGRSQLDPESK
>NC_019693.1|WP_015150588.1|5709397_5710852_+|DUF2157-domain-containing-protein
MVSEKFRRQLRTEARSWTMEGLISEDQYQELSSRYGFESLDRPNQIRFVAILVGLGALLISSGAIALVQANWDIWSRETKTAILVGLFIAVNLCAFYLWGDPLGRSYRFPKWQTRTGHGLFFLSSLLLGLNMSLIGEIFLMSPSLGEFSLIWGLAVLVMAYSLRLTGCGILATLLIGAGYWPGLAQVYQGEGLFWIRTVILHLPLISAFLLVPLAYWCRSPWIFGLATLVLIQSVQVNLIVGFSLLNVPNHWMLAIAYALPPALLWSYDDQPWQVTSLFEGSKDIPHFRPIARTFALIFLALSFYVISFHWFWSSTSPLSPWDPTIAEIPLQQGFAYLLDVLIVLGSWLALVWHFGSPGENFRRFSSPDAYLNHAIALVIAIATGMLFWHFGIQPLPLLGPLIFNILLFLLAYGLMRRGLTQGDRRIFWWGTLLLTLQILTRVLEYETGLVLKSIVFVLCGMATIAIGLAVGSRIQPVEQEDLT
>NC_019693.1|WP_015150589.1|5711123_5711819_+|GDYXXLXY-domain-containing-protein
MENEQPSSPQKIKPSLVIGRFLIPLFIQTAAMLTVAFSAVQTERNGELVTLETEPVNLSKFIRNSANRVSYNISSFQKLEEIPGWEELPGTPVPCPRNNQPRNRQKNQCNPDAKLLDPDLTLYVILEPPTTEETGEVPTPWVAVGLSGDRPMELGENQVMIKGKSSEDLVEYEGEKFYLMRSQREEILETLDLTDQEEQLEPLMIQLKVNPRGYAVPVKLWIGDRNYSLSN

Crispr_ID: NC_019693_63

• CRISPR_ID: NC_019693_63
• CRISPR_location: 5789186-5790985
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 23 spacers
• Cas_protein_info: csx3,WYL,cas10,cmr3gr5,cmr4gr7,cmr5gr11,cmr6gr7

Consensus repeat of NC_019693_63

Consensus_repeat	Method
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	CRISPRCasFinder
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	CRT
TTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	PILER-CR

spacers of NC_019693_63

>63.1|5789221|40|NC_019693|CRISPRCasFinder,CRT
CGGAATACGGGTACTTTGGCTATCAGCTCAAGGATATGGC
>63.2|5789296|45|NC_019693|CRISPRCasFinder,CRT
AACAGGGAAAGATGTTCCCACCTGGCTGATCATCATGGCTAAGTT
>63.3|5789376|38|NC_019693|CRISPRCasFinder,CRT
ACTACGCAACCCGCGAAGTGGTCTACAACACAAAAATG
>63.4|5789449|43|NC_019693|CRISPRCasFinder,CRT
TTGCCGCTATTGCCAAAGCGAACGGGATGGAGAAAACTGGACG
>63.5|5789527|49|NC_019693|CRISPRCasFinder,CRT
TATCTGATAGTCGCATCGTTACGCCTAACAAACCTTTGCTGACTATCCT
>63.6|5789611|38|NC_019693|CRISPRCasFinder,CRT
CATTCCGTTCGACGGATTTATCCCTCCAGGTTCCCCAC
>63.7|5789684|37|NC_019693|CRISPRCasFinder,CRT
AAGCTGAACAAATTGCCAAAGTCTCAATTGATGCAAT
>63.8|5789756|41|NC_019693|CRISPRCasFinder,CRT
CTCTCGGGAATTGATATCGACCGTGCAGCATACCAAGAGAT
>63.9|5789832|41|NC_019693|CRISPRCasFinder,CRT
GGGCAAGGGTATGATGTTCTCTTGGACTTCAACCCCGCTAC
>63.10|5789908|45|NC_019693|CRISPRCasFinder,CRT
GGTTTCGTACACTGCGTATGTGAACTATGCTCCCGTGGTAAATAG
>63.11|5789988|42|NC_019693|CRISPRCasFinder,CRT
GTTTCAAGGAATCGATAACTCAATCGCAACCGTGGTGTTGCA
>63.12|5790065|45|NC_019693|CRISPRCasFinder,CRT
TTTCTTTAACCTCGATAGTCAATCCCATTCCTCAGCGTTTTCCGT
>63.13|5790145|42|NC_019693|CRISPRCasFinder,CRT
AGTCACAAACCAGCTAATCATTAACGAAACTTTCTTCGGGGA
>63.14|5790222|40|NC_019693|CRISPRCasFinder,CRT
TCAAAGACTACATCGCCGCCCTTGAAACCGCTGAAATCGT
>63.15|5790297|46|NC_019693|CRISPRCasFinder,CRT
ACGCCCCCGTTGTGGATATAACCACTACAGGTACGAACGACAAAGC
>63.16|5790378|44|NC_019693|CRISPRCasFinder,CRT
GGAGAAGCAGTTGTAGGTCTCGGAGTGTCAACCGGCACCCGAGG
>63.17|5790457|39|NC_019693|CRISPRCasFinder,CRT
TTTTCCGTGTAAATAGTGGAACATCCTGGACGGTAATCA
>63.18|5790531|40|NC_019693|CRISPRCasFinder,CRT
GTCAATTTTTACAAGACGCTACAGAAGCCATCTACACCGT
>63.19|5790606|41|NC_019693|CRISPRCasFinder,CRT
ATGCTTCCGTAGTTTTCGACTAAGCTACCCTATGCTAATTT
>63.20|5790682|37|NC_019693|CRISPRCasFinder,CRT
CCGAAGAATCCCGTTCCGAGGTGTATTACCGAGGATA
>63.21|5790754|43|NC_019693|CRISPRCasFinder,CRT
GGGAAGGTAACTCCTTCACACGAGCCGATGCAGGAGCGATGTT
>63.22|5790832|41|NC_019693|CRISPRCasFinder,CRT
TTCAATGCTAATGCTGAAATCACTTCCAATTTCTCTGCGAA
>63.23|5790908|43|NC_019693|CRISPRCasFinder,CRT
GGAAACCAACGATTGACACGACTATCGAATGGTTTAATAATAA
>63.24|5789221|41|NC_019693|PILER-CR
CGGAATACGGGTACTTTGGCTATCAGCTCAAGGATATGGCG
>63.25|5789296|46|NC_019693|PILER-CR
AACAGGGAAAGATGTTCCCACCTGGCTGATCATCATGGCTAAGTTG
>63.26|5789376|39|NC_019693|PILER-CR
ACTACGCAACCCGCGAAGTGGTCTACAACACAAAAATGC
>63.27|5789449|48|NC_019693|PILER-CR
GAAATTGCCGCTATTGCCAAAGCGAACGGGATGGAGAAAACTGGACGG
>63.28|5789531|50|NC_019693|PILER-CR
TATCTGATAGTCGCATCGTTACGCCTAACAAACCTTTGCTGACTATCCTG
>63.29|5789615|39|NC_019693|PILER-CR
CATTCCGTTCGACGGATTTATCCCTCCAGGTTCCCCACG
>63.30|5789688|38|NC_019693|PILER-CR
AAGCTGAACAAATTGCCAAAGTCTCAATTGATGCAATG
>63.31|5789760|42|NC_019693|PILER-CR
CTCTCGGGAATTGATATCGACCGTGCAGCATACCAAGAGATG
>63.32|5789836|42|NC_019693|PILER-CR
GGGCAAGGGTATGATGTTCTCTTGGACTTCAACCCCGCTACG
>63.33|5789912|46|NC_019693|PILER-CR
GGTTTCGTACACTGCGTATGTGAACTATGCTCCCGTGGTAAATAGG
>63.34|5789992|43|NC_019693|PILER-CR
GTTTCAAGGAATCGATAACTCAATCGCAACCGTGGTGTTGCAG
>63.35|5790069|46|NC_019693|PILER-CR
TTTCTTTAACCTCGATAGTCAATCCCATTCCTCAGCGTTTTCCGTG
>63.36|5790149|43|NC_019693|PILER-CR
AGTCACAAACCAGCTAATCATTAACGAAACTTTCTTCGGGGAG
>63.37|5790226|41|NC_019693|PILER-CR
TCAAAGACTACATCGCCGCCCTTGAAACCGCTGAAATCGTG
>63.38|5790301|47|NC_019693|PILER-CR
ACGCCCCCGTTGTGGATATAACCACTACAGGTACGAACGACAAAGCC
>63.39|5790382|45|NC_019693|PILER-CR
GGAGAAGCAGTTGTAGGTCTCGGAGTGTCAACCGGCACCCGAGGG
>63.40|5790461|40|NC_019693|PILER-CR
TTTTCCGTGTAAATAGTGGAACATCCTGGACGGTAATCAG
>63.41|5790535|40|NC_019693|PILER-CR
GTCAATTTTTACAAGACGCTACAGAAGCCATCTACACCGT
>63.42|5790609|42|NC_019693|PILER-CR
AATGCTTCCGTAGTTTTCGACTAAGCTACCCTATGCTAATTT
>63.43|5790685|38|NC_019693|PILER-CR
GCCGAAGAATCCCGTTCCGAGGTGTATTACCGAGGATA
>63.44|5790757|44|NC_019693|PILER-CR
GGGGAAGGTAACTCCTTCACACGAGCCGATGCAGGAGCGATGTT
>63.45|5790835|42|NC_019693|PILER-CR
GTTCAATGCTAATGCTGAAATCACTTCCAATTTCTCTGCGAA
>63.46|5790911|44|NC_019693|PILER-CR
TGGAAACCAACGATTGACACGACTATCGAATGGTTTAATAATAA

CRISPR arrays and Neighbor proteins around NC_019693_63

CRISPR arrays

The CRISPR arrays of NC_019693_63

>merge|NC_019693|63|5789186-5790985|CRISPRCasFinder,CRT,PILER-CR
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAGCGGAATACGGGTACTTTGGCTATCAGCTCAAGGATATGGCGTTTCCAACGAGTCCGATTTTAACTAATCGGTAAGAACAGGGAAAGATGTTCCCACCTGGCTGATCATCATGGCTAAGTTGTTTCCAACGAGTCCGATTTTAACTAATCGGTAAGACTACGCAACCCGCGAAGTGGTCTACAACACAAAAATGCTTTCCACCGAGTCCGATTTTAACTAATCGGGAAATTGCCGCTATTGCCAAAGCGAACGGGATGGAGAAAACTGGACGGTTTCCAACGAGTCCGATTTTAACTAATCGGTAAGTATCTGATAGTCGCATCGTTACGCCTAACAAACCTTTGCTGACTATCCTGTTTCCAACAAGTCCGATTTTAACTAATGAGTAAGCATTCCGTTCGACGGATTTATCCCTCCAGGTTCCCCACGTTGCCAACGAGTCCGATTTTAACTAATCGTTAAGAAGCTGAACAAATTGCCAAAGTCTCAATTGATGCAATGTTTCCAACAAGTCCGATTTTAACTAATCGGTAAGCTCTCGGGAATTGATATCGACCGTGCAGCATACCAAGAGATGTCTCCAACGAGTCCGATTTTAACTAATGGGTAAGGGGCAAGGGTATGATGTTCTCTTGGACTTCAACCCCGCTACGTTTCCAACAAGTCCGATTTTAACTAATCGGTAAGGGTTTCGTACACTGCGTATGTGAACTATGCTCCCGTGGTAAATAGGTTTCCAACGAGTCCGATTTTAACTAATCGGTAAGGTTTCAAGGAATCGATAACTCAATCGCAACCGTGGTGTTGCAGTTTCCAACGAGTCCGATTTTAACTAATCGGTAAGTTTCTTTAACCTCGATAGTCAATCCCATTCCTCAGCGTTTTCCGTGTTTCCAACAAGTCCGATTTTAACTAATCGGTAAGAGTCACAAACCAGCTAATCATTAACGAAACTTTCTTCGGGGAGTTTCCCCCGAGTCCGATTTTAACTAATCGGTAAGTCAAAGACTACATCGCCGCCCTTGAAACCGCTGAAATCGTGTTTTCAACAAGTCCGATTTTAACTAATCGGTAAGACGCCCCCGTTGTGGATATAACCACTACAGGTACGAACGACAAAGCCTTTCCAACGAGTCCTATTTTAACTAATCGGTAAGGGAGAAGCAGTTGTAGGTCTCGGAGTGTCAACCGGCACCCGAGGGTTTCCAACGAGTCCGATTTTAACTAATCGGTAAGTTTTCCGTGTAAATAGTGGAACATCCTGGACGGTAATCAGTTTCCAATGAGTTCACTTTTAGTTAATCGGTAAGGTCAATTTTTACAAGACGCTACAGAAGCCATCTACACCGTGTTTCCAACGAGTCCGATTTTAACTAATCGGTAAAATGCTTCCGTAGTTTTCGACTAAGCTACCCTATGCTAATTTGTTTCCAACGAGTCCGATTTTAACTAATCGGTAAGCCGAAGAATCCCGTTCCGAGGTGTATTACCGAGGATAGTTTCCAACGAGTCCGATTTTAACTAATCGGTAAGGGGAAGGTAACTCCTTCACACGAGCCGATGCAGGAGCGATGTTGTTTCCAACGAGTCCGATTTTAACTAATCGGTAAGTTCAATGCTAATGCTGAAATCACTTCCAATTTCTCTGCGAAGTTTTCAACGAGTCCTATTTTAACTAATCGGTAATGGAAACCAACGATTGACACGACTATCGAATGGTTTAATAATAAGTTTCCAACGAGTCCGATTTTAACTAATCGGTAAT

>NC_019693|63|61|5789186-5790985|CRISPRCasFinder
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	CGGAATACGGGTACTTTGGCTATCAGCTCAAGGATATGGC
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	AACAGGGAAAGATGTTCCCACCTGGCTGATCATCATGGCTAAGTT
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	ACTACGCAACCCGCGAAGTGGTCTACAACACAAAAATG
CTTTCCACCGAGTCCGATTTTAACTAATCGGGAAA	TTGCCGCTATTGCCAAAGCGAACGGGATGGAGAAAACTGGACG
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	TATCTGATAGTCGCATCGTTACGCCTAACAAACCTTTGCTGACTATCCT
GTTTCCAACAAGTCCGATTTTAACTAATGAGTAAG	CATTCCGTTCGACGGATTTATCCCTCCAGGTTCCCCAC
GTTGCCAACGAGTCCGATTTTAACTAATCGTTAAG	AAGCTGAACAAATTGCCAAAGTCTCAATTGATGCAAT
GTTTCCAACAAGTCCGATTTTAACTAATCGGTAAG	CTCTCGGGAATTGATATCGACCGTGCAGCATACCAAGAGAT
GTCTCCAACGAGTCCGATTTTAACTAATGGGTAAG	GGGCAAGGGTATGATGTTCTCTTGGACTTCAACCCCGCTAC
GTTTCCAACAAGTCCGATTTTAACTAATCGGTAAG	GGTTTCGTACACTGCGTATGTGAACTATGCTCCCGTGGTAAATAG
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	GTTTCAAGGAATCGATAACTCAATCGCAACCGTGGTGTTGCA
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	TTTCTTTAACCTCGATAGTCAATCCCATTCCTCAGCGTTTTCCGT
GTTTCCAACAAGTCCGATTTTAACTAATCGGTAAG	AGTCACAAACCAGCTAATCATTAACGAAACTTTCTTCGGGGA
GTTTCCCCCGAGTCCGATTTTAACTAATCGGTAAG	TCAAAGACTACATCGCCGCCCTTGAAACCGCTGAAATCGT
GTTTTCAACAAGTCCGATTTTAACTAATCGGTAAG	ACGCCCCCGTTGTGGATATAACCACTACAGGTACGAACGACAAAGC
CTTTCCAACGAGTCCTATTTTAACTAATCGGTAAG	GGAGAAGCAGTTGTAGGTCTCGGAGTGTCAACCGGCACCCGAGG
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	TTTTCCGTGTAAATAGTGGAACATCCTGGACGGTAATCA
GTTTCCAATGAGTTCACTTTTAGTTAATCGGTAAG	GTCAATTTTTACAAGACGCTACAGAAGCCATCTACACCGT
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAA	ATGCTTCCGTAGTTTTCGACTAAGCTACCCTATGCTAATTT
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	CCGAAGAATCCCGTTCCGAGGTGTATTACCGAGGATA
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	GGGAAGGTAACTCCTTCACACGAGCCGATGCAGGAGCGATGTT
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	TTCAATGCTAATGCTGAAATCACTTCCAATTTCTCTGCGAA
GTTTTCAACGAGTCCTATTTTAACTAATCGGTAAT	GGAAACCAACGATTGACACGACTATCGAATGGTTTAATAATAA
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAT

>NC_019693|63|5|5789186-5790985|CRT
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	CGGAATACGGGTACTTTGGCTATCAGCTCAAGGATATGGC
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	AACAGGGAAAGATGTTCCCACCTGGCTGATCATCATGGCTAAGTT
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	ACTACGCAACCCGCGAAGTGGTCTACAACACAAAAATG
CTTTCCACCGAGTCCGATTTTAACTAATCGGGAAA	TTGCCGCTATTGCCAAAGCGAACGGGATGGAGAAAACTGGACG
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	TATCTGATAGTCGCATCGTTACGCCTAACAAACCTTTGCTGACTATCCT
GTTTCCAACAAGTCCGATTTTAACTAATGAGTAAG	CATTCCGTTCGACGGATTTATCCCTCCAGGTTCCCCAC
GTTGCCAACGAGTCCGATTTTAACTAATCGTTAAG	AAGCTGAACAAATTGCCAAAGTCTCAATTGATGCAAT
GTTTCCAACAAGTCCGATTTTAACTAATCGGTAAG	CTCTCGGGAATTGATATCGACCGTGCAGCATACCAAGAGAT
GTCTCCAACGAGTCCGATTTTAACTAATGGGTAAG	GGGCAAGGGTATGATGTTCTCTTGGACTTCAACCCCGCTAC
GTTTCCAACAAGTCCGATTTTAACTAATCGGTAAG	GGTTTCGTACACTGCGTATGTGAACTATGCTCCCGTGGTAAATAG
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	GTTTCAAGGAATCGATAACTCAATCGCAACCGTGGTGTTGCA
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	TTTCTTTAACCTCGATAGTCAATCCCATTCCTCAGCGTTTTCCGT
GTTTCCAACAAGTCCGATTTTAACTAATCGGTAAG	AGTCACAAACCAGCTAATCATTAACGAAACTTTCTTCGGGGA
GTTTCCCCCGAGTCCGATTTTAACTAATCGGTAAG	TCAAAGACTACATCGCCGCCCTTGAAACCGCTGAAATCGT
GTTTTCAACAAGTCCGATTTTAACTAATCGGTAAG	ACGCCCCCGTTGTGGATATAACCACTACAGGTACGAACGACAAAGC
CTTTCCAACGAGTCCTATTTTAACTAATCGGTAAG	GGAGAAGCAGTTGTAGGTCTCGGAGTGTCAACCGGCACCCGAGG
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	TTTTCCGTGTAAATAGTGGAACATCCTGGACGGTAATCA
GTTTCCAATGAGTTCACTTTTAGTTAATCGGTAAG	GTCAATTTTTACAAGACGCTACAGAAGCCATCTACACCGT
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAA	ATGCTTCCGTAGTTTTCGACTAAGCTACCCTATGCTAATTT
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	CCGAAGAATCCCGTTCCGAGGTGTATTACCGAGGATA
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	GGGAAGGTAACTCCTTCACACGAGCCGATGCAGGAGCGATGTT
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	TTCAATGCTAATGCTGAAATCACTTCCAATTTCTCTGCGAA
GTTTTCAACGAGTCCTATTTTAACTAATCGGTAAT	GGAAACCAACGATTGACACGACTATCGAATGGTTTAATAATAA
GTTTCCAACGAGTCCGATTTTAACTAATCGGTAAT

>NC_019693|63|6|5789187-5790984|PILER-CR
TTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	CGGAATACGGGTACTTTGGCTATCAGCTCAAGGATATGGCG
TTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	AACAGGGAAAGATGTTCCCACCTGGCTGATCATCATGGCTAAGTTG
TTTCCAACGAGTCCGATTTTAACTAATCGGTAAG	ACTACGCAACCCGCGAAGTGGTCTACAACACAAAAATGC
TTTCCACCGAGTCCGATTTTAACTAATCGGGAAA	TTGCCGCTATTGCCAAAGCGAACGGGATGGAGAAAACTGGACGGTTTC
CAACGAGTCCGATTTTAACTAATCGGTAAGTATC	TGATAGTCGCATCGTTACGCCTAACAAACCTTTGCTGACTATCCTGTTTC
CAACAAGTCCGATTTTAACTAATGAGTAAGCATT	CCGTTCGACGGATTTATCCCTCCAGGTTCCCCACGTTGC
CAACGAGTCCGATTTTAACTAATCGTTAAGAAGC	TGAACAAATTGCCAAAGTCTCAATTGATGCAATGTTTC
CAACAAGTCCGATTTTAACTAATCGGTAAGCTCT	CGGGAATTGATATCGACCGTGCAGCATACCAAGAGATGTCTC
CAACGAGTCCGATTTTAACTAATGGGTAAGGGGC	AAGGGTATGATGTTCTCTTGGACTTCAACCCCGCTACGTTTC
CAACAAGTCCGATTTTAACTAATCGGTAAGGGTT	TCGTACACTGCGTATGTGAACTATGCTCCCGTGGTAAATAGGTTTC
CAACGAGTCCGATTTTAACTAATCGGTAAGGTTT	CAAGGAATCGATAACTCAATCGCAACCGTGGTGTTGCAGTTTC
CAACGAGTCCGATTTTAACTAATCGGTAAGTTTC	TTTAACCTCGATAGTCAATCCCATTCCTCAGCGTTTTCCGTGTTTC
CAACAAGTCCGATTTTAACTAATCGGTAAGAGTC	ACAAACCAGCTAATCATTAACGAAACTTTCTTCGGGGAGTTTC
CCCCGAGTCCGATTTTAACTAATCGGTAAGTCAA	AGACTACATCGCCGCCCTTGAAACCGCTGAAATCGTGTTTT
CAACAAGTCCGATTTTAACTAATCGGTAAGACGC	CCCCGTTGTGGATATAACCACTACAGGTACGAACGACAAAGCCTTTC
CAACGAGTCCTATTTTAACTAATCGGTAAGGGAG	AAGCAGTTGTAGGTCTCGGAGTGTCAACCGGCACCCGAGGGTTTC
CAACGAGTCCGATTTTAACTAATCGGTAAGTTTT	CCGTGTAAATAGTGGAACATCCTGGACGGTAATCAGTTTC
CAATGAGTTCACTTTTAGTTAATCGGTAAGGTCA	ATTTTTACAAGACGCTACAGAAGCCATCTACACCGTGTTT
CCAACGAGTCCGATTTTAACTAATCGGTAAAATG	CTTCCGTAGTTTTCGACTAAGCTACCCTATGCTAATTTGTTT
CCAACGAGTCCGATTTTAACTAATCGGTAAGCCG	AAGAATCCCGTTCCGAGGTGTATTACCGAGGATAGTTT
CCAACGAGTCCGATTTTAACTAATCGGTAAGGGG	AAGGTAACTCCTTCACACGAGCCGATGCAGGAGCGATGTTGTTT
CCAACGAGTCCGATTTTAACTAATCGGTAAGTTC	AATGCTAATGCTGAAATCACTTCCAATTTCTCTGCGAAGTTT
TCAACGAGTCCTATTTTAACTAATCGGTAATGGA	AACCAACGATTGACACGACTATCGAATGGTTTAATAATAAGTTT
CCAACGAGTCCGATTTTAACTAATCGGTAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015150658.1|5794006_5795770_+|CRISPR-associated-protein	cas10	cd09679_cas10_CAS-III	gnl|CDD|187810
NC_019693.1|WP_015150647.1|5774236_5776156_-|GTPase-family-protein	unknown	unknown	gnl|CDD|226124
NC_019693.1|WP_044197734.1|5771103_5773194_-|hypothetical-protein	unknown	unknown	gnl|CDD|224276
NC_019693.1|WP_015150646.1|5773297_5773621_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044195720.1|5795688_5796759_+|CRISPR-associated-protein-Cmr3	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	gnl|CDD|187879
NC_019693.1|WP_015150656.1|5791216_5792569_+|TIGR03985-family-CRISPR-associated-protein	WYL	mkCas0075_WYL_CAS-I:CAS-III	gnl|CDD|274901
NC_019693.1|WP_015150654.1|5787821_5788148_+|CRISPR-associated-protein-Csx3	csx3	pfam09620_csx3_CAS-I:CAS-III	gnl|CDD|370583
NC_019693.1|WP_015150651.1|5783324_5785886_+|leucine--tRNA-ligase	unknown	unknown	gnl|CDD|234743
NC_019693.1|WP_071884363.1|5799998_5800346_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150660.1|5796775_5797639_+|hypothetical-protein	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl|CDD|224255
NC_019693.1|WP_044197737.1|5778028_5779600_-|B12-binding-domain-containing-radical-SAM-protein	unknown	unknown	gnl|CDD|379101
NC_019693.1|WP_156824090.1|5801952_5804403_-|response-regulator	unknown	unknown	gnl|CDD|274362
NC_019693.1|WP_015150663.1|5800609_5801659_+|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|366703
NC_019693.1|WP_156823937.1|5792889_5793918_-|hypothetical-protein	unknown	unknown	gnl|CDD|187878
NC_019693.1|WP_044195714.1|5773830_5774013_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150655.1|5788144_5789035_+|CRISPR-associated-protein	csx3	mkCas0115_csx3_CAS-I:CAS-III	gnl|CDD|370583
NC_019693.1|WP_015150662.1|5798099_5799842_+|hypothetical-protein	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl|CDD|224520
NC_019693.1|WP_015150661.1|5797638_5798103_+|hypothetical-protein	cmr5gr11	mkCas0065_cmr5gr11_CAS-III-B	unknown
NC_019693.1|WP_015150648.1|5776484_5777561_-|fatty-acid-desaturase	unknown	unknown	gnl|CDD|215275
NC_019693.1|WP_015150650.1|5779756_5782696_-|calcium-binding-protein	unknown	unknown	gnl|CDD|197594

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_015150658.1|5794006_5795770_+|CRISPR-associated-protein	cas10	cd09679_cas10_CAS-III	8.5e-27	88.8	1.0
NC_019693.1|WP_015150660.1|5796775_5797639_+|hypothetical-protein	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	2.1e-21	71.3	0.0
NC_019693.1|WP_015150655.1|5788144_5789035_+|CRISPR-associated-protein	csx3	mkCas0115_csx3_CAS-I:CAS-III	2.9e-100	329.6	0.0
NC_019693.1|WP_015150662.1|5798099_5799842_+|hypothetical-protein	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	1.4e-11	39.2	0.1
NC_019693.1|WP_015150661.1|5797638_5798103_+|hypothetical-protein	cmr5gr11	mkCas0065_cmr5gr11_CAS-III-B	5.2e-67	218.3	6.1
NC_019693.1|WP_015150656.1|5791216_5792569_+|TIGR03985-family-CRISPR-associated-protein	WYL	mkCas0075_WYL_CAS-I:CAS-III	4.2e-179	591.1	0.4
NC_019693.1|WP_015150654.1|5787821_5788148_+|CRISPR-associated-protein-Csx3	csx3	pfam09620_csx3_CAS-I:CAS-III	4.6e-30	98.3	0.1
NC_019693.1|WP_044195720.1|5795688_5796759_+|CRISPR-associated-protein-Cmr3	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	3.3e-18	61.1	0.6

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015150658.1|5794006_5795770_+|CRISPR-associated-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	2.75203e-25
NC_019693.1|WP_015150647.1|5774236_5776156_-|GTPase-family-protein	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	3.75798e-85
NC_019693.1|WP_044197734.1|5771103_5773194_-|hypothetical-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.235e-33
NC_019693.1|WP_015150660.1|5796775_5797639_+|hypothetical-protein	gnl|CDD|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	5.52085e-18
NC_019693.1|WP_044195720.1|5795688_5796759_+|CRISPR-associated-protein-Cmr3	gnl|CDD|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	5.45101e-06
NC_019693.1|WP_015150656.1|5791216_5792569_+|TIGR03985-family-CRISPR-associated-protein	gnl|CDD|274901	TIGR03985, hypothetical_protein_sll7078, CRISPR-associated protein, TIGR03985 family. Members of this protein family belong to CRISPR-associated (Cas) gene clusters. The majority of members are Cyanobacterial.	1.91179e-113
NC_019693.1|WP_015150654.1|5787821_5788148_+|CRISPR-associated-protein-Csx3	gnl|CDD|370583	pfam09620, Cas_csx3, CRISPR-associated protein (Cas_csx3). This entry is encoded in CRISPR-associated (cas) gene clusters, near CRISPR repeats, in the genomes of several different thermophiles: Archaeoglobus fulgidus (archaeal), Aquifex aeolicus (Aquificae), Dictyoglomus thermophilum (Dictyoglomi), and a thermophilic Synechococcus (Cyanobacteria). It is not yet assigned to a specific CRISPR/cas subtype (hence the x designation csx3).	2.65398e-38
NC_019693.1|WP_015150651.1|5783324_5785886_+|leucine--tRNA-ligase	gnl|CDD|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NC_019693.1|WP_044197737.1|5778028_5779600_-|B12-binding-domain-containing-radical-SAM-protein	gnl|CDD|379101	pfam13282, DUF4070, Domain of unknown function (DUF4070). This is a bacterial domain often found at the C-terminus of Radical_SAM methylases.	4.22105e-69
NC_019693.1|WP_156824090.1|5801952_5804403_-|response-regulator	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	3.35883e-62
NC_019693.1|WP_015150663.1|5800609_5801659_+|M23-family-metallopeptidase	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	5.14126e-21
NC_019693.1|WP_156823937.1|5792889_5793918_-|hypothetical-protein	gnl|CDD|187878	cd09747, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as Cas02710 family.	1.4976e-05
NC_019693.1|WP_015150655.1|5788144_5789035_+|CRISPR-associated-protein	gnl|CDD|370583	pfam09620, Cas_csx3, CRISPR-associated protein (Cas_csx3). This entry is encoded in CRISPR-associated (cas) gene clusters, near CRISPR repeats, in the genomes of several different thermophiles: Archaeoglobus fulgidus (archaeal), Aquifex aeolicus (Aquificae), Dictyoglomus thermophilum (Dictyoglomi), and a thermophilic Synechococcus (Cyanobacteria). It is not yet assigned to a specific CRISPR/cas subtype (hence the x designation csx3).	2.10376e-22
NC_019693.1|WP_015150662.1|5798099_5799842_+|hypothetical-protein	gnl|CDD|224520	COG1604, COG1604, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.03641e-09
NC_019693.1|WP_015150648.1|5776484_5777561_-|fatty-acid-desaturase	gnl|CDD|215275	PLN02498, PLN02498, omega-3 fatty acid desaturase.	8.51803e-140
NC_019693.1|WP_015150650.1|5779756_5782696_-|calcium-binding-protein	gnl|CDD|197594	smart00237, Calx_beta, Domains in Na-Ca exchangers and integrin-beta4. Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins).	1.23946e-18

Protein sequences

>NC_019693.1|WP_015150655.1|5788144_5789035_+|CRISPR-associated-protein
MSGRVQLTVNELQARNGELYQCLEIATSGKIEPELLGSLTLPRELDFSKGIILWGAAPIWFTSHLVQRCDPAPWVGCYDLQLGSVVVVASRTRELAAAESFRLVPSRPPGPALFIGGPPNSGKSVLSYALVRGLRGANPDRRIHLHRAQWDGEGNWAIEAGDRALVDSLRQQHKAGWSQRFFQHHGEAVGHIREAVDLVLVDFGGKPKPRDVMVRDRCTHYLIITSDPEALAQWHDFCQVQGKLTPVAVIHSVLEDRVEVLQTEPFLEIIAGPWMRGESARIPEALLSAVMKLLVM
>NC_019693.1|WP_015150654.1|5787821_5788148_+|CRISPR-associated-protein-Csx3
MEAIALTVIPHHTRDGIRYQHIRIEIISDDGIVEPDDLKSLELPPLDGSQGVVFEGKSPIWVYAYLTHEAHATAWVGCYDPRLKGAVVVATHTRGVGVGSVLPLELPA
>NC_019693.1|WP_015150651.1|5783324_5785886_+|leucine--tRNA-ligase
MESRYNPASLEEKWQQTWTERQLYQTPETRDRPKFYALSMFPYPSGSLHMGHVRVYTITDVIGRLKRMQGYRVLNPMGWDAFGLPAENAAIERGIHPAKWTYQNIAQMKQQLERLGIAFDWTREVATCSPDYYKWTQWIFLQFFNAGLAYQKEAAVNWDPIDQTVLANEQVDNEGRSWRSGAKVERKLLKQWFFKITDYAEQLLQDLDQLTGWPERVKLMQANWIGKSVGAYLEFPIVDSTEKVAVFTTRPDTVYGVTYVVLAPEHPLTRQVTTSDRLAAVESFIAEVSNQSELERTADDKPKRGIPTGGTAINPFTGEEIPIWIADYVLYEYGTGAVMGVPAHDVRDFKFAREQNLPIKQVIVRADAADEKAQLKEAYTEPGIVINSELFNGMESPTAKGEIIAYAEKQKWGKARVQYRLRDWLISRQRYWGAPIPVIHCPSCGAVPVPDEDLPVQLPEDVAFSGRGLSPLSQLESWVNVPCPSCGEPAKRETDTMDTFIDSSWYFLRYPDAQNADKAFDTQQVNDWLPVDQYVGGIEHAILHLLYSRFFTKVLRDRGLLNFDEPFQRLLTQGMVQGLTYKNPQTGKYIPSAQVNASDPKDPEMGEPLQVFYEKMSKSKYNGVDPLEVLGNYGADTARMFILFKAPPEKDLEWEDADVEGQFRFLNRVWRLVTEYAETTPAKQVKGELSKAEKELRRAIHTAIKEITEDLDGEYQFNTAVSELMKLSNALNDADCKNSAIYTEGIKTLLILLAPFAPHIAEELWQGIGNQTSVHEQSWPGVDLDALVVDEITLVIQISGKTRGTIQVPAQATREELEQYARESEVAQKYIAGQEIKKAIVVPGKLVNFVLGK
>NC_019693.1|WP_015150650.1|5779756_5782696_-|calcium-binding-protein
MTFIFGDNQGNTLIGTDDNDTIIGGDGNDSLLGNAGEDILFGGLGDDTLIGGPGADIFVLGSGRDRIVDFQKGVDRIAVSRDLRTAQIRLEPIFERTGNGNSNPVAIATQVVVIQNGGPQVIGEVLGSINLEATDFLSTTLDPLASVVEFAATNFTVQEGVPSVEVRLLRTGNLSETASVTVLPTDGTAIAGEDYIGGPRVVTFAPRQSQAVVTIPIIDDNLVQPTETFSVSLVNATENLRLGGRSQSTITILDNDVSLSFGEQTFTLNDQGEAVATITVLRQGIIESTVGATITLAPNLPTPPADLNLPQIPVNFAPGVTAQTVTIPIVNELIEAGVQTLSLTLTTPTGGATVGTSNTASFTLSENPLTPVTVQFSETEFQGLEDSTPLVPVTVTRTGFLNRPVTVTLVLEEETATAPEDFDDTPIVVTFPSGETTQTITIPIVNDNIIEPDETIALTLVDPTGGATLGTPTTATFTIVDNNVALRFTRPDFSAVEDGTPIAPVQVERIGFTNIPTGVTIGLSDGTATAPFDYDPTPLAVDFAPGETLQTVEIPIVDDDIVEPDETINLTLLNSTGEATLGEPSTAVFTIIDNDVFLQFSEANFIVNEDGTAIAPVTVTREGRLDQPFSVAIALTDGTATAPFDYDNTPILVNFAPGETVQTVAVPIVDDTESEPTETLQLTLTNPSTGAQIGPQNAATLAILDNDIRLEFSAPTFSVQEDGTQILAVTVTRAGGLHLPAGATLVLGDGTATAPFDYDNTPIPISFAPGETVQTVTIPIVNDAIAEVAETINLALVNPTPGVEIGAQSSATLVIPRSDLPAFLNFEGVGNLDPVSGFYGDRGITFSPNALGIISTDALDALGFPDEFGGNFAPPPSGTTALTYGEQGAVVMNVEGGFDNQLSFFYASPFASHTVTLYDGLGASGNILASVPLSTTAAGSLPHVYAEFEQVTLPFAGVARSVSFGSVPNKLILDDILLG
>NC_019693.1|WP_044197737.1|5778028_5779600_-|B12-binding-domain-containing-radical-SAM-protein
MRTLLVYPLFPPTFWSYNKILELVDRQVLLPPLGLITVAAILPQTWDFKLVDRNIRPVTEAEWDWAELVIFSAMIVQKQDLLDQIREAKRRGKSVAVGGPYPTSVPDEVAVANPDFMILDEGEITLPMFIDALEKGETQGVFRTLEKPDVSETPVPRYDLLELDAYDSMSVQFSRGCPFQCEFCDIIVLYGRKPRTKTPEQLLAELDCLYELGWRRSVFMVDDNFIGNKRNVRLLLQALKVWQADHQYPFRFNTEASIDLAADTDLMDLMVDCNFDAVFLGIETPDEDSLSMTKKFQNTRSSLTESVDKIIDAGLRPMAGFIIGFDGEKKDASSRIVKFVEEAAIPTAMFGMLQALPNTALWHRLEKEGRLRVNSRQDINQSTLMNFVPTRPITDIAQEYIEAFWQLYDPEVFLDRTYRCFLKLGAPKCQPPAKFPSWVDLRALGIIIWRQGIKRKTRWKFWHHLFSVMRHNPGVWEAYLTVCAHNEHFLEYRQIVRDEIEAQLREWKRQEALSPVAVTSEVA
>NC_019693.1|WP_015150648.1|5776484_5777561_-|fatty-acid-desaturase
MQANTVLNQTTGTVSQTQTQELPFTLQDVKAAIPAECFEPSIFKSLSYFFLDVGIIAGLYAIAYNLDSWFFFPIFWVMQGTMFWALFVVGHDCGHGSFSKLKWLNNLIGHLSHIPILVPYHGWRISHRTHHGNTGNLDTDESWYPVSEEKFNRMPWYEKLFRFYLPLLAYPLYLFKRSPDRQGSHFLPSSPLFRPSEKWDIVTSSVLWVMMVGFLGVLTYQFGWVFLVKYYLVPYIIFVMWLDLVTFLHHTEDDIPWYRGEDWYFLKGALSTIDRDYGFINPIHHNIGTHVAHHIFLNMPHYHLKTATEAIKPLLGDYYRSSNEPFLKSFIRSYWSCHFVPNTGSKVYYQSAWKPKSK
>NC_019693.1|WP_015150647.1|5774236_5776156_-|GTPase-family-protein
MVRLKTWQWVVLALPIAAIVSFLLVAAGTQIHEWNLNWIWAIFTLVLVGWRWLLVQWTQPMMAEMEAAIAQVNQDIEESKQQNTGPTADEATQKAEIALQKILETSRNDAPIWEDLQTFGNRCQEVVTAIALIYNPEVKYPLLNIYIPQAYGLIRGTVDDLDRWMQQLSPALNQVTVGQAFQAYEMYRKLEPSARKLFQVWNWVQWFVNPAVAAARLASQGSSNRATQELLVNLGQLLREAALRNLSRQAATLYGNRILPETAAPMSIPALPKAKTQTLREIISQTEPVENIAQKPVNILLVGRTGAGKSSLINTLFDSDRAEVDLLPSTDLISNYHWQSEGGETLILWDTPGYEQAKRADLRQMVLDYGTTADLLLLVTPALDPALQMDVDFLKEIKAEVSDLPAIAIVTQVDRLRPIREWNPPYDWVWGDKPKEKSIREATQYRTEQLGEYCDRILPIVTQDSQQGRVAWNTDTLAVALIEAIDPAKQQRLARFLRDRESRIVTSAKIIDRYTFQMATTQGVTSLLKTPVLQFISTLSTGSPTLAYALAEQIPVEQLPMVIGKLQMAYDLFNLLNIDAKPFQFDLLSLWPLLRDNRGTSDRNAWAFGHALVEYWTQKLTLEQLRSRFESYLEQQPTS
>NC_019693.1|WP_044195714.1|5773830_5774013_-|hypothetical-protein
MAIALHQQNQPLLLGGYGLTGRIDLNKKPPNLWGFAMHISQSPLILLLTLEKEIRQSTDL
>NC_019693.1|WP_015150646.1|5773297_5773621_-|hypothetical-protein
MNPQERQKLERQLQDLEAQIHHPQPLQTSTPDTPSLKSVYQQLTLWYQGLPDRGKVVAIAVGGVFALSAVSTVLNLLRLAFTLAAVGVLGFVGYKLFLASKSSNPNQ
>NC_019693.1|WP_044197734.1|5771103_5773194_-|hypothetical-protein
MTLFPRRLAASTVELALITLSALVPLSLGWHATRYLNVQPVPLNPVLVTLEGAIARTLALPPTCPHPRGRRCTRLVPPLVNFLWTIGPIAALSVSIWQLYLLGLTGQTLPKRWLRLQVVTDSGKAPGFGRALLREAVGRWGVTLTSAYLIWLITGAVPDLVILGVTTALMVALDGLWSYFDPKCRTLHDRLAGTWVRSSRHSVSGPSKKMNSSNSKQVGIQFEAGGPLERMPESQPGLDQWWNRIRLQSSAKIVLALAVGLGAILGTFVTTQLYIQSQENARTQAARDQEKFLTWVQQFAPDERQGAILGLASLDNPEAQYQILADMLALETDAAQLDVLQQALVSSGGRSLPYLQKLNQSTRTDLDSLRYSTNEEQLEVVQLRLQATQRAIAKLLQLYSTEFDSLDLSRTHLGQVTTEAAPFTLVLEKTDLSGIRFRGAILSHASFKSSQFSSPGPDRRFGSLDDQKADFTASILTDADFTGAFLSHVLLAYSNLSRAKLDRANLSNAQLTGANLSSVQAIGADLREADLTNATLVGAQLVQANLTGILAIGARFPRVVATDATLAKANLMRSDWQGADLSRGNFTQSNLQNANMSGTKLAGANLSFAQLQNANFQQTDLTSVNFQGANVEGADFQGAVFFKPHTQNGDRLIQSPDPATAGFLRGVDFSNARNLDNKQIVYICAQGGIYPLCSQP
>NC_019693.1|WP_015150656.1|5791216_5792569_+|TIGR03985-family-CRISPR-associated-protein
MTEPTFCDPPTVEVLQWLARGSLKKNFLKAVRLWVHLQLLYGESDSRLGIVHPFTYADWRNTFFTDSHPRDESIPPLHDCHCPCARTAACWLFDEVMGCSELEWRESLSQTACNPDNLEELLESRLFGVTRRSLAEDLKTLAELGCLKKGDRSQYDKVQTWPVGMIARFPALTTSQGAMTFNFLQPDLAAIAENLSQELGGYPRFFLQVEYVVPKMTLDAIHDWQEQLKQLWQQHPIPTVLLTYNSAKLERIVECAVYPVCIYYVQRAVYLVGFGRNPRGEVNWYNYRCDRIDNLEPLPWNDPRIPQPLILHHQNQTLPTPEYIQDQMAQGWGFDFYQPNLLMLLRFDPHHHRRYIEDTERHETFESVTYKRAQQLIKQQASPGECQALLKILNQRSESDAYYQAFYREGDPNVLMRLNAWRPYVEVFLPWKLRERMAGDVRQEWGFYGD
>NC_019693.1|WP_156823937.1|5792889_5793918_-|hypothetical-protein
MHPLLEIVMKPHNPQPKLSSRLRKVTKMGFGVLEKGARVTMRVAIQGKDAIARMVTSAWKGTQAIARRCGSAIGGFWSSLQLGRIFRRVGLPIWVLVGLAIASLIVDNLLKLLELAIRYFLATTPIPTPKDYLVHFIMIVVGLGLIVVMSLGFKLRRPLTQGRFISDGLTQPDGKKGLILLVSNPNSAMFSIEYHYETKRTLATVWLIPSDESQLIKFGGSSQDKAQEIQQRCEQLSMNLQKSDASNNRPTLPPLQVTLLKGVSPADAQETFSTVNKIYRQSHYSADEIAADFTGGTKPMSVGMIMACLKRDRVLEYVSYNKGQSFGPYIIDYQHSAFDLIS
>NC_019693.1|WP_015150658.1|5794006_5795770_+|CRISPR-associated-protein
MSQSGYTAITFAPVQGFIEKSRKLRDLYGSSFLLSYLSRVLCQAASQQGLNVISPAIINVTQGTPNQIIIQGLFTKSDAEATFKQAWQNIVETCRQWIETQVPSFNYCWKREWKDWSHHAWEFFWATGDTITAARESLNDIKRPRDWVGINWKGESSTLSGTDAIAWPKLGLVNPKTRPAKPEKQEIEEFYAALSQKFGETYLDRIPKRLNGTEREAVAKKIGEAIITPREQLSIPELIKRLITVDAVAEKIQLQIKHPRIELSEEFIQKALQSTTIEIPEKPFREVNRHEEQSWTGWFQGDGDRMGKFLQELAAKGEEIERQELKQFSQSLMEWGENELKPYMKTSKLGRIVYAGGDDFMGVLFQSATPGKLTAAECLQWFAHLPELWKKHGYADKITVSVGFVWAAPNVPQRDVLQHGRLAEKAAKSCGRDRLALRVLFNSGNHLEWVCPWRFLDILSAYCDRSQKTQNWAHIYQDIAILEARHAFTNQKIKIAEALADIYFPTYPDILDPKNWWNTGGIAGILGEPETYHEDGKISQIKVNAALNEWIINLAKVGFHLCSNTSSSSNPWDSSMVAPEDTSLLKT
>NC_019693.1|WP_044195720.1|5795688_5796759_+|CRISPR-associated-protein-Cmr3
MFQYLILIQPLGFLYGSAGRYLSPENLVGRSGTSFPPSAATLSGIFAAEWQTASEKEKLKTLQLAGPFWAEERNVQNFYVATPFNCLVKDKIIQHILTWQGDKWLLPSGDKPPNDKFENGTWVGIKDWQNLQGKEEEKPQVKTNPWKFLPHLHPRLRENERHVNTDAADHQGSLFLENAVQLNPETCLVYLSNEEIPEGWYRFGGEGHIVEIRCEAIAEPAKTLLEQPLQRSFALITPAIWGSNRLSYREPRVNQGNEWQSVWYDNESNPKSLLTQRPQPMRFRLGDCKDGPPHQPKLLSRGRYAVPPGTVYIVDQPQKAWQEWPENWFPTEGYSFKRWGCGLSLPLNGAVSDPLT
>NC_019693.1|WP_015150660.1|5796775_5797639_+|hypothetical-protein
MYHKAYGIIETLAPLHVGASAGEETGNLNLIFRDQFTLTGIIPGSSIRGRFRADMRRPPNSNGNVGHWYGHEAVKGREDGGTTEARVKFEYASLVWLPVFCPGQPIVWVTSPLLLKRYKQIANITPPVPQPYTASPDLEGRQVPGTQKKVLFFNLGFLEIDHQVDLNPWIPTGTNLSTKSLVVVDDRDIGNIHDMALYRQSRVKLLDGMKKVDTERGAFFNTEALPVGSILAFPVALKERGWQPFGPLNSQPYSQELYFGGLESIGFGRCNVTLVGDSLIQPQEVKQ
>NC_019693.1|WP_015150661.1|5797638_5798103_+|hypothetical-protein
MAWTSYSLDQKAQQLVLDARQRDRDAMAATGKRKNSLNQSFKMRESVAYGLERFWGEHLRLQLKEPDKSLYWKETWDALVEVMQQSGITVPNDRVNVDNTLAVKAMAQKLWQINKEDQRIILAVLTQLCDCIVWWTQRYKGSAELNTNETEDEG
>NC_019693.1|WP_015150662.1|5798099_5799842_+|hypothetical-protein
MTIPNADRHIPLMFQAQTRGRSQLQYINSETDKQDSQRWADQWTERIYPTAPQFGEGVETRTYTISWRFVTNGGQDEGIIRPEIGAYGWPIYPGSSMKGVFRHACKQIASDRLSVYCGDAEQAGILRFHGGYPISDEWRNNLVDLVHPQQKWQVEVNITTKKPSGESGYALISLDRPTLQFGISTTDTQQTNWDEVWKIWETALGYGIGCRTSSGYGMPENRIEAEAKHPIQVQGTRLCQVYLKGQGQCPQLVDKTPEFRPNLFRGALRGHALRIFGGLTDAETAKDLVEMLFGGVQGHGTVGLLTLAWKPTSVNIKTFTGGHEVPTYDVAGQLQWILTRSLPESQQKLLQKLMRMLMRFAMLIGGFGKSWRRADHRLFYPEYYHKNNKNDQNKALIGCHWEWEKSSLINDNKVRGLKFVDPFLNDVRKTALDWIESLGITPTPDTPADWREAWHPHNVEVWGRVSQGREDCKAVQWLHQPYQKSDRYTGQKTQTIKQTSVTGSIHQIGRLWHRMYPLVRVKTTIEDGQEKKKAIVTQEFLELLTIFPDDSQDCTNFIEFLHQEAGLKYQRDSFQKLWPK
>NC_019693.1|WP_071884363.1|5799998_5800346_+|hypothetical-protein
MNLFRFVDRMMKLPKELEEQLTTEIIEGREERQMPFMSQFEEIAQEKGIERGTVQNQRENTLAVLEVRFGDVPPEVVEAVNGIEDIPTLKQLHRQAIAIGSVAQFQELLNSVIEG
>NC_019693.1|WP_015150663.1|5800609_5801659_+|M23-family-metallopeptidase
MFRKPKIIATILLAFAIAVAVHWIGFNRPNFAQSPIPETTIAANSLQLALPIDCTLDEDCFILLYPDRDPGPGEVDFGCGRQTYDGHKGTDFGIVNTDKMNAGVAVMASAPGKVLRVRDGVSDRLITDPQQVAALEGRECGNGVFIEHGNGWETQYCHLRNGSVVVRPGMEVDTGTVLGMVGASGAASFPHVHITALYEGQVVDPFVGPEAGPGCQVSRSPIWTVPLDYTPTGAIDAGFADTPPDMDALWEGGFPQGELSTDIPALLFWVHTYGVLPGDSYRFKLIAPNGETIAEDTKEINSPSKTWMGFVGKRNNPDRPIIPGVWRGEYQLTRDGEVLVDLVREIEVM
>NC_019693.1|WP_156824090.1|5801952_5804403_-|response-regulator
MPGVVIHANLTSQILSSALDNRSMLYATPKSLKWGLIFLSSGYSALLGSLWLRTRWSGPGIILGAVVLIGTSYLAFLSGWLIPFFTPILALVSAGVFSIGYTLWSNLKLSYHQLAKYAKTLEEKNQELKRLDGLKDEFLANTSHELRTPLNGIIGIADSLIDGVTGPLSEPTIFNLETITTSGRRLSHLVNDILDFSQLKHKNIELQLKPLDLRAIAQVVLNLSKPLIEDKDLQLINAIPADFIAVNADENRVQQILHNLIGNGIKFTESGLVEVSAKIVDDFVAITVTDTGIGIPQDKLSRIFESFEQADGSTAREYGGTGLGLAIAKQLIELHHGSIDVESEVGKGSCFTFTLPRTTAAVAPKKPPLIYPERLNRTPAPVTQQTSLNNPVLATEIYISEGAEFKILIVDDEPINLQVLANTLSLQNYAITRAANGLKALEIIENGFKPDLILLDVMMPRMTGYEVCEKIRQKFAAIDLPIVMLTAKNQVSDLVEGFSAGANDYLMKPFNKNELLTRIKTHIRLAKINAAYGRFVPHDFLHFLGQESIVDVKLGNHIKKEMTVLFSDIRDFTSLSEEMSPEETFHFINSYLSRVSPIIRDRNGFIDKYIGDAIMALFPNSADDAVSGAIAMQHQVKLFNEHRQENGQVPIQIGIGLHTGSLMLGTIGEAERMESTVISDAVNLASRLEGLTKQYGSAILISEDTLNKLENREFYQYRFLDRVQVKGKKVSVAVFEIYNSEPHDCIELKSKTLAQFELAIACYQEGNFEQSQTLFEQILTLNPSDRAALLYLQRCHKYIKQGVPKDWIGIEAMSEK

Crispr_ID: NC_019693_64

• CRISPR_ID: NC_019693_64
• CRISPR_location: 5968097-5968196
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_64

Consensus_repeat	Method
TAGGGGCGATTCGCGAATCGCCC	CRISPRCasFinder

spacers of NC_019693_64

>64.1|5968120|54|NC_019693|CRISPRCasFinder
GAAAAAAACCCCCCATTTTCACCAAAACCTCTAAACAATCACCCAAAACTCCTG

CRISPR arrays and Neighbor proteins around NC_019693_64

CRISPR arrays

The CRISPR arrays of NC_019693_64

>merge|NC_019693|64|5968097-5968196|CRISPRCasFinder
TAGGGGCGATTCGCGAATCGCCCGAAAAAAACCCCCCATTTTCACCAAAACCTCTAAACAATCACCCAAAACTCCTGTAGGGGCGATTCTCGAATCGCCC

>NC_019693|64|62|5968097-5968196|CRISPRCasFinder
TAGGGGCGATTCGCGAATCGCCC	GAAAAAAACCCCCCATTTTCACCAAAACCTCTAAACAATCACCCAAAACTCCTG
TAGGGGCGATTCTCGAATCGCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015150791.1|5956767_5957700_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NC_019693.1|WP_015150804.1|5971957_5972164_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150803.1|5971465_5971753_-|membrane-protease-regulatory-membrane-protein	unknown	unknown	gnl|CDD|376684
NC_019693.1|WP_044197767.1|5966207_5967641_-|membrane-protein	unknown	unknown	gnl|CDD|100082
NC_019693.1|WP_156823948.1|5958791_5959025_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150795.1|5959989_5961198_+|NupC/NupG-family-nucleoside-CNT-transporter	unknown	unknown	gnl|CDD|224883
NC_019693.1|WP_015150794.1|5959281_5959716_-|ubiquinol-cytochrome-c-reductase-iron-sulfur-subunit	unknown	unknown	gnl|CDD|223795
NC_019693.1|WP_015150802.1|5970145_5970994_-|M48-family-metalloprotease	unknown	unknown	gnl|CDD|320692
NC_019693.1|WP_015150792.1|5957999_5958530_-|DUF4330-domain-containing-protein	unknown	unknown	gnl|CDD|379510
NC_019693.1|WP_015150810.1|5976474_5978583_+|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|273776
NC_019693.1|WP_015150809.1|5974930_5976277_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_019693.1|WP_015150808.1|5974197_5974908_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_019693.1|WP_015150806.1|5973325_5973655_-|four-helix-bundle-copper-binding-protein	unknown	unknown	gnl|CDD|153434
NC_019693.1|WP_015150799.1|5964590_5966174_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|224117
NC_019693.1|WP_015150797.1|5962384_5963143_+|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|277316
NC_019693.1|WP_015150796.1|5961516_5962260_+|DUF1995-family-protein	unknown	unknown	gnl|CDD|370448
NC_019693.1|WP_156823949.1|5968217_5968373_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150801.1|5969002_5970040_+|AI-2E-family-transporter	unknown	unknown	gnl|CDD|223701
NC_019693.1|WP_044195803.1|5963399_5964368_+|glycosyltransferase	unknown	unknown	gnl|CDD|223515
NC_019693.1|WP_015150805.1|5972570_5972789_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015150791.1|5956767_5957700_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.36636e-27
NC_019693.1|WP_015150803.1|5971465_5971753_-|membrane-protease-regulatory-membrane-protein	gnl|CDD|376684	pfam01957, NfeD, NfeD-like C-terminal, partner-binding. NfeD-like proteins are widely distributed throughout prokaryotes and are frequently associated with genes encoding stomatin-like proteins (slipins). There appear to be three major groups: an ancestral group with only an N-terminal serine protease domain and this C-terminal beta sheet-rich domain which is structurally very similar to the OB-fold domain, associated with its neighboring slipin cluster; a second major group with an additional middle, membrane-spanning domain, associated in some species with eoslipin and in others with yqfA; a final 'artificial' group which unites truncated forms lacking the protease region and associated with their ancestral gene partner, either yqfA or eoslipin. This NefD, C-terminal, domain appears to be the major one for relating to the associated protein. NfeD homologs are clearly reliant on their conserved gene neighbor which is assumed to be necessary for function, either through direct physical interaction or by functioning in the same pathway, possibly involve with lipid-rafts.	4.26209e-10
NC_019693.1|WP_015150801.1|5969002_5970040_+|AI-2E-family-transporter	gnl|CDD|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	6.47897e-41
NC_019693.1|WP_015150795.1|5959989_5961198_+|NupC/NupG-family-nucleoside-CNT-transporter	gnl|CDD|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	2.6265e-156
NC_019693.1|WP_015150794.1|5959281_5959716_-|ubiquinol-cytochrome-c-reductase-iron-sulfur-subunit	gnl|CDD|223795	COG0723, QcrA, Rieske Fe-S protein [Energy production and conversion].	6.12817e-22
NC_019693.1|WP_015150802.1|5970145_5970994_-|M48-family-metalloprotease	gnl|CDD|320692	cd07333, M48C_bepA_like, Peptidase M48C Ste24p bepA-like, integral membrane protein. This family contains peptidase M48C Ste24p protease bepA (formerly yfgC)-like proteins considered to be putative metallopeptidases, containing a zinc-binding motif, HEXXH, and a COOH-terminal ER retrieval signal (KKXX). They proteolytically remove the C-terminal three residues of farnesylated proteins. They are integral membrane proteins associated with the endoplasmic reticulum and golgi, binding one zinc ion per subunit. In eukaryotes, Ste24p is required for the first NH2-terminal proteolytic processing event within the a-factor precursor, which takes place after COOH-terminal CAAX modification (C is cysteine; A is usually aliphatic; X is one of several amino acids) is complete. Mutation studies have shown that the HEXXH protease motif, which is extracellular but adjacent to a transmembrane domain and therefore close to the membrane surface, is critical for Ste24p activity. Several members of this family also contain tetratricopeptide (TPR) repeat motifs, which are involved in a variety of functions including protein-protein interactions. BepA has been shown to possess protease activity and is responsible for the degradation of incorrectly folded LptD, an essential outer-membrane protein (OMP) involved in OM transport and assembly of lipopolysaccharide. Overexpression of the bepA protease causes abnormal biofilm architecture.	1.42922e-87
NC_019693.1|WP_015150792.1|5957999_5958530_-|DUF4330-domain-containing-protein	gnl|CDD|379510	pfam14221, DUF4330, Domain of unknown function (DUF4330). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 165 and 177 amino acids in length. There is a single completely conserved residue G that may be functionally important.	6.30363e-85
NC_019693.1|WP_015150810.1|5976474_5978583_+|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	2.04306e-34
NC_019693.1|WP_015150809.1|5974930_5976277_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.33244e-52
NC_019693.1|WP_015150806.1|5973325_5973655_-|four-helix-bundle-copper-binding-protein	gnl|CDD|153434	cd08026, DUF326, Cysteine-rich 4 helical bundle widely conserved in bacteria. This functionally uncharacterized protein forms a 4-helical bundle with a bromodomain-like topology. It is present in major bacterial lineages and contains highly conserved cysteines in a repeated pattern, whose sidechains appear buried. Some family members have been (mis)annotated as putative ferredoxins.	1.48776e-23
NC_019693.1|WP_015150799.1|5964590_5966174_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	gnl|CDD|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	1.77464e-16
NC_019693.1|WP_015150797.1|5962384_5963143_+|serine/threonine-protein-phosphatase	gnl|CDD|277316	cd00144, MPP_PPP_family, phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain. The PPP (phosphoprotein phosphatase) family is one of two known protein phosphatase families specific for serine and threonine. This family includes: PP1, PP2A, PP2B (calcineurin), PP4, PP5, PP6, PP7, Bsu1, RdgC, PrpE, PrpA/PrpB, and ApA4 hydrolase. The PPP catalytic domain is defined by three conserved motifs (-GDXHG-, -GDXVDRG- and -GNHE-). The PPP enzyme family is ancient with members found in all eukaryotes, and in most bacterial and archeal genomes. Dephosphorylation of phosphoserines and phosphothreonines on target proteins plays a central role in the regulation of many cellular processes. PPPs belong to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	2.98774e-24
NC_019693.1|WP_015150796.1|5961516_5962260_+|DUF1995-family-protein	gnl|CDD|370448	pfam09353, DUF1995, Domain of unknown function (DUF1995). This family of proteins are functionally uncharacterized.	8.26812e-77
NC_019693.1|WP_044197767.1|5966207_5967641_-|membrane-protein	gnl|CDD|100082	cd06161, S2P-M50_SpoIVFB, SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation. SpoIVFB (sporulation protein, stage IV cell wall formation, F locus, promoter-distal B) is one of 4 proteins involved in endospore formation; the others are SpoIVFA (sporulation protein, stage IV cell wall formation, F locus, promoter-proximal A), BofA (bypass-of-forespore A), and SpoIVB (sporulation protein, stage IV cell wall formation, B locus). SpoIVFB is negatively regulated by SpoIVFA and BofA and activated by SpoIVB. It is thought that SpoIVFB, SpoIVFA, and BofA are located in the mother-cell membrane that surrounds the forespore and that SpoIVB is secreted from the forespore into the space between the two where it activates SpoIVFB.	8.34164e-05
NC_019693.1|WP_015150808.1|5974197_5974908_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	9.74117e-83
NC_019693.1|WP_044195803.1|5963399_5964368_+|glycosyltransferase	gnl|CDD|223515	COG0438, RfaG, Glycosyltransferase [Cell envelope biogenesis, outer membrane].	4.27718e-09

Protein sequences

>NC_019693.1|WP_044197767.1|5966207_5967641_-|membrane-protein
MDWICPDLTPYWTLTPIPDSDQILLKAIEGNLRVIFSASEGYALAYFTGEYTVLEIQTRCEQQFPGEISADFIEVLLDKLIELNILAQENPGGELGSLDAEQSAGDRPKNSQQLKSCVQWINHPGGYWILRNADDFTFLQMSDFDKVIIDQLGRRSPTAIIEEFCITPQELKNLLRLLTTSAMLEGTTLPTPPRGKFNPMQLLYFRIPLFNPDPWLNRHIDGIRWIWTKPFAVILFLCLAASAILGIRQWEVIFYTGQQLMEANGPALIIPFAGLSMLVVAFHELGHAFTLKNFGGVVPNMGLLLMMFMPAAYTNTTDSYCLSRFKRVLVVGAGLLVQFAIWAGALWFWNWTNPSSWLHTASYLLMVAALVTVAINLNPMAKFDGYYLAVAMTGINNLRGRSFALYGNLLQGKPLREPTENIMILAIYAPLSLAYIYFVFGFLFARIADWSLSKIPMTALLLLTIWLVYFFFPRDKQ
>NC_019693.1|WP_015150799.1|5964590_5966174_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit
MTATNNPSPKSPLKVVPPKAIAQPSAVPTPPVIQTPPAASPSKVATPSKSYGKWLMMAMVLAGGVMVARMPISNYVIGEAEVTSRLDERQRLVMPVSGQLTLKVKSNADVEEGDIIAEVSSPEIENQVAEADRSLQHGNAALFAAQKRLTLAETDLQYAQKNVEIAQDRAEKKRREIQEIIAGNKLPIIRQIEAEISSIESEIDGVKNSQVGLDSKIVEIQTQITALKSEKTTLKEQLGSLEETIEDYQVVVDEGALARNVLRQEKDKKLRLINQIDQQSFAIKGKQEQIEQTHSEILQRENIIEQKNQLIAGKFEQIKQVEKEIEELRDERENEVEQQLGLQRSVEQKVEAAKADIQSEMERVQKAEAELNRLRDRQATLILTADTAGTVLTPDLDLLDQNTIQSGQEIMRIVNLSQLTATVQVSQEDGNLVQRDQTVVFKVRDPYSPSYRARVQDISPMIAPDKSGTNPMLTLTILIDNPDDILRPGGQGFAHIETGQMRVYQKVQHELNKLFNLDKYFVGFSKE
>NC_019693.1|WP_044195803.1|5963399_5964368_+|glycosyltransferase
MTQPSIYFVCYPDTNVPIGGVKMLYRHVDVLNKNGFSAFIIHDDEGFRCDWFKNQTQIAYLTQIKLRAEDIFVMPETATPKSGNLLPGIRKVIYNQGCYNTFNEYSFDKHQLETPYHSPEVVAVLVASENSFNYLKYVFPQVRLFRIHHSIDTEVFYYHPIKKKQICWMDRKMQRDAQQVINILKFRNALNGFELIPIENKPQKEVAQIFRESLLFLSFCYSEGFSLPPAEAMASGCLAVGYHGWGGQEYFLPDFSFPVESGDIIRFAHTVEKLIATYNTQPQLLMEKHKKAADFIQKHYSAEQEERDIVAAWREIIKLKKG
>NC_019693.1|WP_015150797.1|5962384_5963143_+|serine/threonine-protein-phosphatase
MSKINYRRIAIGDVHGHYHALVKLLDAIAPTADDRLYFLGDLIDRGPDSASVVKLVRDHKFTCLLGNHEHLLINACGNGKVNQPALQAWRYSGGQNTLTSYPKLYSHPSEALLEDVAWMQTLPLYVDLGDAWLVHAGVHPDLPIHDQGAEDFCWIRTPFHNIRKPYFPNKLIVVGHTITFTFKGIKPGQLAKGNGWLDIDTGAYHPLSGWLSAFDLTHRQVYQVNLFKGKVRKLSLQDAVVSIHPKQGAVCP
>NC_019693.1|WP_015150796.1|5961516_5962260_+|DUF1995-family-protein
MPELPKDLDEAIAQAKTATKAALDDGYRLMQVEIGIPELKVQPIAEEFLPIFEDLFGDHFKVYFPDAGAAALARRDWGERPYIIRGLSEPKGQMQPEDQGFLFVEPSAVEVNTLEKMCEQAGDRPTVILMPKLENVAIIGIGLAGRQLRERFLSTIESCYYIQPSQGYAVFRYYPSPWQVWLETGDTYQLISETATKPVGDDLERLITQATSTAEESTDEGTNPPLTAPKKPGLMTNMKRFLRALTQ
>NC_019693.1|WP_015150795.1|5959989_5961198_+|NupC/NupG-family-nucleoside-CNT-transporter
MERVISLVGLITFVGIAYAFSVNRQAIRWRTVLWGIGLQLFFALFILRTTPGLALFKFLGDRVNDFLNLADVGSAFVFGENFREHFFAFKILPTIIFFSACITLLYHYGILQRVVQGVAWVMMRTMKTSGAESLSSAANIFVGQLEAPLLIKPYIATMTNSELHAVMTGGFATIAGGVLAAYISFGIPVEHLLSASVMSAPASLAVSKLLYPETEKSSTAGQIELSGESPYINAIDAITSGAIEGLKLALNVAAMLIAFLGLVALLNAVLGWMGSWVGIPSLSLELILSYLMAPIAWLMGVPWADVEAVGMLLGKKTILNEFIAYLDLKQLIENQAISPRSVVIATYALCGFSNLGAIAIQIGGISAIAPNRQGDLARLGVRAMLAGSIACFMTACIAGLLL
>NC_019693.1|WP_015150794.1|5959281_5959716_-|ubiquinol-cytochrome-c-reductase-iron-sulfur-subunit
MKRREFLNWVGVGGVASFLPMAIAACTPSGESTTEVSTPPDNFEAVGTVFELETQGQILNENFQNGAISVTRNPEDSQLLYAVNPTCTHNRCLVDWNAAERKYICPCHGAEYSPDGTVIKGPAEENLPPYLVKIEGEQVVVQAI
>NC_019693.1|WP_156823948.1|5958791_5959025_-|hypothetical-protein
MQPLDPAGCSTSSPNQPIPDSARDKLAESILTAAKNTSKTTQAAMFVRPDLPQGDRQDATDLTAISIAQFSPATCRP
>NC_019693.1|WP_015150792.1|5957999_5958530_-|DUF4330-domain-containing-protein
MKILDRQGRLFGKISILDLGAALVILLVIIGIFFFPGTSGSVAQIGGVTTKPVEVDLIIRGLSVRDPEALLREFQEKGKTNVIIRNQPYGQVDVKSVQLLTRTLAVPQPDGSVKALPDPRQEESFSANLLMTLGGNARITDDGPVLGNSKVKIGTPIELEGTTYNFNASVIDVRIQ
>NC_019693.1|WP_015150791.1|5956767_5957700_+|alpha/beta-hydrolase
MFIPPGFDQGSIVTSLGRMVYYTNRPEFWQGGPSESGDRPTQPTLLFLHGFGGGSSAYEWSKVYPAFASDYRILAPDLIGWGRSEHPERNYQIEDYLSTLTEFIQQTCPEPVVAIASSLTAAFTIRVAIAHPEFFKSLILTTPSGLSDFGENYSSSFFAQLVKTPILDQLLYRTGIATEVGIRGFLQSRQFANPDLIYPEIVQAYLQSALEPNGEYAALSFVRGDLCFDLSRDIPQLTIPTAFIWGRQSQFTGPELGKRLASLNPSAIREFIQLETVGLTPQLEVPAVTIGLIRRFLLELTERSPESTRI
>NC_019693.1|WP_156823949.1|5968217_5968373_-|hypothetical-protein
MCNARFYDRINRNDRSLERIRQYIADNPLKWHEDTENPECDREMPFNEIPF
>NC_019693.1|WP_015150801.1|5969002_5970040_+|AI-2E-family-transporter
MSKPSRQNLWSQLNNYKLFRYLLLLTLGWAIIQVLGYFQSVIVIFIFAAILAFLLNYPVKWIQRWVPHNIAVILVFLASLIMFGGLAITLGVAVLSQGQQLLEQSPELLQSLLDLLDYIQEVLARRNLQLDLTAIEDRLREEALAGIGVGLMTVQKILSNLVDLILIAVVAFFMLLDGRQIWDLFLKLFPSRLRSNVTLAIQKNFLGFFWGRLILSVFFAVSCFVVFVILDIPYALILAAVGGFFDLIPGIGATLGISLISLILLPQGIWLSIKVLVTCILLQQVEENLLMPRIMKDSININPVIMFLALLIGARVAGLLGIFLAIPISGVLISLGDFDDMKGDK
>NC_019693.1|WP_015150802.1|5970145_5970994_-|M48-family-metalloprotease
MFNLYAWISHRVNRRWIYPIISAILAIALVVSSSYPSLAKNPRRLIGPGLEVLQLSTMSDAQEVALGQQINQQLLSSQFRRYGNTQINTYVREIGDRLAAQSDRPNLPYTFQVVQDDSINAFATMGGFVYVTTGLLQAMDNEAQLAGVIGHEIGHIVYKHSIRQMREVIIARGLAGAAGVDSNIVVQLGVELALRLPRSRQHEYEADRGALDILINTGYSPRGLVQFFEKLLGKPSPPTFLSTHPASSDRIAALEQMIPPGQANQGMGLNEPAYRERIRPLL
>NC_019693.1|WP_015150803.1|5971465_5971753_-|membrane-protease-regulatory-membrane-protein
MFSFLNNLFAPHPARLKEYQDPNLKYTLGRPGEIGIVDEMIRGPYIAGRVHFRGSYWPASCDREIVLGPGEPVRIVGIHCITLLVQPVGVFEEPS
>NC_019693.1|WP_015150804.1|5971957_5972164_-|hypothetical-protein
MEDKKPQSEPLRRFITPQQLGLVAFFILFWAIALHYAVARFWQVQDDCPVVVPQSSASVRDIEGCADE
>NC_019693.1|WP_015150805.1|5972570_5972789_-|hypothetical-protein
MVLSNWFEFILLTLFNATLCVLLPRLLTLNWSQIFSQLKGQSKRLPKITGEDVSNPGLVSSLKSTPLPNQVQ
>NC_019693.1|WP_015150806.1|5973325_5973655_-|four-helix-bundle-copper-binding-protein
MPHQINQSSIDVIVDCAVKCEHCADECIGSMPDCARLCRDCSQMCWTIAGFMSRGSQFIEQVSRACIDICETCAKECETHDNPHCQKCAEACRQSLEVFKKISTVAVGR
>NC_019693.1|WP_015150808.1|5974197_5974908_+|response-regulator-transcription-factor
MKILLVEDEPDLGAAIKRTLEREAYVVDWAKDGREGYEYIESYRLQPVEMPYTLAIFDWLLPALSGIELCKRLRASGSALPVLMLTAKDSMEDKVAGLDAGADDYLVKPFGMAELLARLRALQRRSPQLQPQQIQVGNLTLDYGTRTLYCHQETGEFVAISMTNKEFQLLEYLMRHPQQIINRDRILDRLWELGSEPGSNVVAAQMRLLRRKLAEQGYDRLIETVYGLGYRFKSEE
>NC_019693.1|WP_015150809.1|5974930_5976277_+|HAMP-domain-containing-histidine-kinase
MNHNQLFRQTRLQLACWYAGVMGVILGLCGWGMYEAIAHAHWMTLDRELESVAGTLHDSLEPVLQEPGQLEPEVGRLLPDLCTQNEQCWNRQFNRERHAIGALHQGDYYVRLLDLTDNLIAVAGVSPDGLPGREGAETWQTFTDSQGTRFHQISVVLHTQDSRDWGSLEVGRSLKEFDDYLGAVKVIMLIGLPIALFGVGTASWGLAGVAMQPIYQSYRQIQQFTADAAHELRTPLAAIRATVESNLRVDSTNFEDIIETLKTVDRQNLRLSQLVNDLLLLSRMDQQELPLKPSLCCLNDVISDVEEEIAVLAIASQVKLTTEVRVQQAVRVKGNEEELYRLLFNLVSNGIQYTPVGGKVTLILDASDRHAIIQVKDTGIGIHPQDLNQIFDRFYRVNSDRARHTGGSGLGLAIAQAIAKTHHGNIQVQSELGQGSLFTIRLPILESA
>NC_019693.1|WP_015150810.1|5976474_5978583_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MRSPNYSNLTPTLLAAILLVMTPAAVLAHPGHGNEFEGGGDVSAPTGGIEVDSQTLERMGILVEPVQQAVMDVGIKVTGQIETLPNETVEVTAPVAGKIIQLLVQPGDAVQAGNAVAILSSPELAALRVDALQKQAEAESNLKQAEANWQLAQQNYQRQVTIADAEIAQAEQQVATAQSRSERDQNLVEERGVLTAAEEGYRRQVELAESEIATAQKQVEIAQSRYEGDRQLVEEGGVLSIARENYQRQMELAEAEIAQAETELGVAQERFERDQELVEQGAIPRRQMLDSEAQFAAAKSAVKRAQSRLGQLQAESEVKRAEIDLPLRDLRESEELLARSQTELARAQSRLGQLQAQADVKRAEADLPLRDLRESEDLLAQARGQLTRARSRQGVIAAEAELKRADAELQAAKSQVNLSDRTYQTRLNQLNITPDEQGTVTVTSPITGIVAHREITPGQSVEAAGTSLMKIQNQALVGAIANLYEKDLQQVKIGQPVNITVASFPNRIFTGRIDYIASDVQGESRVIPVRAEVDNIGGELKPGMFAELEIATDRTSEMVTSIPESAIVEVNNLPVVYVQNGQQFQPVEVRLGQQFGERIEVKGGLFAGDRIVIEGAMQLYAQSLRGGSNSSHDHPEETETNQMNAAGLIQWGWLPVGGAIAGVAFWLGRRSKPMPKSTAPYPTFPSEIGEFSETAIDVMPKS

Crispr_ID: NC_019693_65

• CRISPR_ID: NC_019693_65
• CRISPR_location: 6095715-6095812
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_65

Consensus_repeat	Method
CCGGAGGACCCCACCCTAACCCTCCTCTTG	CRISPRCasFinder

spacers of NC_019693_65

>65.1|6095745|38|NC_019693|CRISPRCasFinder
GTAAGGGGAGGGGACCGGAGGACTGGAGGACCGGAGGA

CRISPR arrays and Neighbor proteins around NC_019693_65

CRISPR arrays

The CRISPR arrays of NC_019693_65

>merge|NC_019693|65|6095715-6095812|CRISPRCasFinder
CCGGAGGACCCCACCCTAACCCTCCTCTTGGTAAGGGGAGGGGACCGGAGGACTGGAGGACCGGAGGACCGGAGGACCCCACCCTAACCCTCCCCTTG

>NC_019693|65|63|6095715-6095812|CRISPRCasFinder
CCGGAGGACCCCACCCTAACCCTCCTCTTG	GTAAGGGGAGGGGACCGGAGGACTGGAGGACCGGAGGA
CCGGAGGACCCCACCCTAACCCTCCCCTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015150907.1|6088538_6089930_-|intein-containing-thymidylate-synthase	unknown	unknown	gnl|CDD|224270
NC_019693.1|WP_015150906.1|6088073_6088505_+|dUTP-diphosphatase	unknown	unknown	gnl|CDD|234802
NC_019693.1|WP_015150922.1|6110474_6111257_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150904.1|6087102_6087645_-|dCMP-deaminase-family-protein	unknown	unknown	gnl|CDD|238613
NC_019693.1|WP_015150920.1|6108165_6108492_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NC_019693.1|WP_015150921.1|6108927_6110268_+|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NC_019693.1|WP_015150903.1|6086512_6087049_+|P-loop-NTPase-family-protein	unknown	unknown	gnl|CDD|168945
NC_019693.1|WP_015150917.1|6104279_6105770_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044197796.1|6085659_6086247_-|adenylate-kinase	unknown	unknown	gnl|CDD|234711
NC_019693.1|WP_044195848.1|6099607_6099910_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150914.1|6095873_6098918_-|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl|CDD|234570
NC_019693.1|WP_015150908.1|6090066_6091722_-|thymidylate-synthase	unknown	unknown	gnl|CDD|238211
NC_019693.1|WP_044195845.1|6091909_6092749_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823953.1|6100523_6103820_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015150919.1|6106324_6107860_-|C-3',4'-desaturase-CrtD	unknown	unknown	gnl|CDD|274272
NC_019693.1|WP_044197798.1|6093051_6093453_+|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl|CDD|223643
NC_019693.1|WP_015150905.1|6087832_6088030_-|DUF2442-domain-containing-protein	unknown	unknown	gnl|CDD|378424
NC_019693.1|WP_156824096.1|6093534_6094977_+|TrkH-family-potassium-uptake-protein	unknown	unknown	gnl|CDD|223246
NC_019693.1|WP_044197807.1|6111319_6114124_-|TIGR02921-family-PEP-CTERM-protein	unknown	unknown	gnl|CDD|131967
NC_019693.1|WP_156824097.1|6099906_6100107_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015150907.1|6088538_6089930_-|intein-containing-thymidylate-synthase	gnl|CDD|224270	COG1351, THY1, Predicted alternative thymidylate synthase [Nucleotide transport and metabolism].	3.18976e-29
NC_019693.1|WP_015150906.1|6088073_6088505_+|dUTP-diphosphatase	gnl|CDD|234802	PRK00601, dut, dUTP diphosphatase.	9.25419e-71
NC_019693.1|WP_015150904.1|6087102_6087645_-|dCMP-deaminase-family-protein	gnl|CDD|238613	cd01286, deoxycytidylate_deaminase, Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the enzyme is allosterically regulated by the ratio of dCTP to dTTP not only in eukaryotic cells but also in T-even phage-infected Escherichia coli, with dCTP acting as an activator and dTTP as an inhibitor.	4.66013e-56
NC_019693.1|WP_015150920.1|6108165_6108492_-|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	2.47577e-14
NC_019693.1|WP_015150921.1|6108927_6110268_+|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.74742e-104
NC_019693.1|WP_015150903.1|6086512_6087049_+|P-loop-NTPase-family-protein	gnl|CDD|168945	PRK07414, PRK07414, P-loop NTPase family protein.	5.4761e-113
NC_019693.1|WP_044197796.1|6085659_6086247_-|adenylate-kinase	gnl|CDD|234711	PRK00279, adk, adenylate kinase; Reviewed.	8.80532e-67
NC_019693.1|WP_015150914.1|6095873_6098918_-|phosphoenolpyruvate-carboxylase	gnl|CDD|234570	PRK00009, PRK00009, phosphoenolpyruvate carboxylase; Reviewed.	0
NC_019693.1|WP_015150908.1|6090066_6091722_-|thymidylate-synthase	gnl|CDD|238211	cd00351, TS_Pyrimidine_HMase, Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the biosynthesis of DNA precursors and are active as homodimers. However, they exhibit distinct pyrimidine base specificities and differ in the details of their catalyzed reactions. TS is biologically ubiquitous and catalyzes the conversion of dUMP and methylene-tetrahydrofolate (CH2THF) to dTMP and dihydrofolate (DHF). It also acts as a regulator of its own expression by binding and inactivating its own RNA. Due to its key role in the de novo pathway for thymidylate synthesis and, hence, DNA synthesis, it is one of the most conserved enzymes across species and phyla. TS is a well-recognized target for anticancer chemotherapy, as well as a valuable new target against infectious diseases. Interestingly, in several protozoa, a single polypeptide chain codes for both, dihydrofolate reductase (DHFR) and thymidylate synthase (TS), forming a bifunctional enzyme (DHFR-TS), possibly through gene fusion at a single evolutionary point. DHFR-TS is also active as a dimer. Virus encoded dCMP-HMase catalyzes the reversible conversion of dCMP and CH2THF to hydroxymethyl-dCMP and THF. This family also includes dUMP hydroxymethylase, which is encoded by several bacteriophages that infect Bacillus subtilis, for their own protection against the host restriction system, and contain hydroxymethyl-dUMP instead of dTMP in their DNA.	9.68214e-14
NC_019693.1|WP_015150919.1|6106324_6107860_-|C-3',4'-desaturase-CrtD	gnl|CDD|274272	TIGR02733, similar_to_to_phytoene_dehydrogenase, C-3',4' desaturase CrtD. Members of this family are slr1293, a carotenoid biosynthesis protein which was shown to be the C-3',4' desaturase (CrtD) of myxoxanthophyll biosynthesis in Synechocystis sp. strain PCC 6803, and close homologs (presumed to be functionally equivalent) from other cyanobacteria, where myxoxanthophyll biosynthesis is either known or expected. This enzyme can act on neurosporene and so presumably catalyzes the first step that is committed to myxoxanthophyll. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_019693.1|WP_044197798.1|6093051_6093453_+|TrkA-family-potassium-uptake-protein	gnl|CDD|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	7.148e-28
NC_019693.1|WP_015150905.1|6087832_6088030_-|DUF2442-domain-containing-protein	gnl|CDD|378424	pfam10387, DUF2442, Protein of unknown function (DUF2442). This family of bacterial and fungal proteins has several members annotated as being putative molybdopterin-guanine dinucleotide biosynthesis protein A; however this could not be verified. Hence the function is not known. This family also includes the DUF3532 that was found to be related and was merged into this family. Members of this family also fall into the NE0471 N-terminal domain-like superfamily, a family of proteins with a unique fold in SCOP:143880.	0.000232451
NC_019693.1|WP_156824096.1|6093534_6094977_+|TrkH-family-potassium-uptake-protein	gnl|CDD|223246	COG0168, TrkG, Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	1.01702e-89
NC_019693.1|WP_044197807.1|6111319_6114124_-|TIGR02921-family-PEP-CTERM-protein	gnl|CDD|131967	TIGR02921, PEP_integral, PEP-CTERM family integral membrane protein. Members of this protein family, found in eighteen genera so far, have a PEP-CTERM sequence at the carboxyl-terminus (see model TIGR02595), but are unusual among PEP-CTERM proteins in having multiple predicted transmembrane segments. The function is unknown. It is proposed that an exosortase (see TIGR02602), recognizes and cleaves PEP-CTERM proteins in a manner analogous to the cleavage of LPXTG proteins by sortase (see Haft, et al., 2006). In at least six species, a gene encoding what appears to be a dedicated (single target) exosortase is adjacent. In that subset, the PEP-CTERM motif takes the form VPEPxxWxL.	0

Protein sequences

>NC_019693.1|WP_156824096.1|6093534_6094977_+|TrkH-family-potassium-uptake-protein
MALVSLWVCVAFREFYAIAPFLLTSLVSFGIGQLLYRSVHQYSEEAHLRHAMITVALSWGLIPLVGAIPFLVIASHLAPLPDASETVILFQNPWNAVFESFSGFTSTGLTMAFNPRELPYCLQWWRSFMEWVGGVGTIVLMLSVLDPSTEPFQLYNAEGRSRRIALTVRGTVRQLWKIYLVYTAVCISIFGVLGMPWWDALNYGLTTSSMGGFDLTPDGIGSYSRMIQLALVPLMIIGAISFAIHVRLIRDRQFSLLWNREEYRALWLLLGVGVVLLFLENYWFQGSFLWIDSLFQWVSALTTCGFNTVKVETWSASAKLLLSVAMAVGGAAGSTVGGLKIKRVLVLYKGVLWHFRRISLRPHQLMRYQLDGKSLGEAEAYRRIEGAAVLAVLWISWLAIGVMVLNRLVPEKYQLSDTIFEAASALSGVGLSTGISHPNLHWDGKLVLILLMWMGRLEIIPVMLLLSALMRKMKARIFKI
>NC_019693.1|WP_044197798.1|6093051_6093453_+|TrkA-family-potassium-uptake-protein
MYFIIVGAGPEGSSLAELALNDGHKVAVIEASEEHARKIVEKYDVEVFHGDIAGGGMLEEAQADKADVLVATTGDDSVNLMTMFLGKDCGIKTLISRVNQSCHQGLFEKLGVQVLVNPEVIIAQHLYGMVQEE
>NC_019693.1|WP_044195845.1|6091909_6092749_-|hypothetical-protein
MYSITQILISDFVEKLREGYYRMYGGLKPDYADIIAWAGGMALENIANSDALYHNVEHTILVTLVGQEILRGKHIREGGVSCEDWLHFTISLLCHDIGYVKGVCREDSEGLYATGINGTMIALDPGCTDASLTPYHVDRGKLFIEERFGGHKLINSEEIKFNIELTRFPVPAEADHQDTVHYPGLVRAADLIGQLSDPRYLKKISALFYEFEETGFNQKVGYRNPGDLRKNYSKFYWGVVHQYIKNGLSCLELTQQGKQIIANLYANVFVVEHEPPKPE
>NC_019693.1|WP_015150908.1|6090066_6091722_-|thymidylate-synthase
MFRNSTQAFYAELKALLESNETVLWGGVELKSGRSRLMKITSPCERVDIIPHLNSNIFAQIAATFWEMAGRKDLRFLYHYLPQALDFFEEEPTQVSSYDSSLKSWHLSKELQKVVQILNTDSSSRNAVINLSQPQLKNSENPGNTAQNWMQFLIRNGKLHLNVCLQSHDMFSGTSGINPFGLSIIQEAVAYWTGTQVGEYCYFISELHLGDRHQNQAQKVLDSYTPKTLYEFGFTPPQFTTPFAEIDSTLSRWFELEHQMRQGSFRITNELSNISDDLVRNSLELLYIYNRHQHGDKPQEIAKLIAQLPPNDFKIATIEYFTRLWNNHEIIPLQPQEKDYFDYLWQRTEPTHSYSFSSIFELLSTLHYKKTLVYKNSWKKHGEALGVFAGISRKYDRLETMFTENVKPTADESVLDTFADLAVYSTKYLTYLAEHYPEMFQHFIHPDLNRDSLQTYWHNEGFDPTSKLLTQRYHASEQWQQISSYQGCFEAIRDAYKELEDIFVNQDWRVSDRRKCSLSADLAIVSLHYLVLASQQEPENFQKFAEAIANL
>NC_019693.1|WP_015150907.1|6088538_6089930_-|intein-containing-thymidylate-synthase
MDRFRVEVITKTPNPQQVIYAAMHQDYSEGFVYDDQDSWPSESKCGELIVKRLLAGERGHYGPIEHVGIVFNCGFFPHSVMQQIRTHRVGISFDVQCLAGDTEVTFLQAGGSLRKIKIAELYDFWANGEKAIRQRLKRGRNGELPGEYRRDCKTRLKKMRLRVLNETTGFFEIGHIKNVIAKGIQPVYRVTLDDGKTLDCTTNHRLFTAEGWQRMGEAVGLVTDEEGQVLELTKSCDVMCNGIPVVSDRLYTNEGLEQQIYKGFSTPEIADNSHYSNNLIQAHPIKVKSVQFLGLEMTYDLEVEGPWHNFVANGMVVHNSNRYTGNRIVDAAKGIRDIEDVFYLRPVGYYSDRQGKRYEYTPQQRDRDLAWCLDAAKRYQVLIEEGTSEEHARGIIPFDVRQHWVVSFNARSLMHLLDLRAKPDAQLECQKLCDLIWPHFQEWVPAIAEWYEKYRLKKGRLSP
>NC_019693.1|WP_015150906.1|6088073_6088505_+|dUTP-diphosphatase
MKLKIYPLHPDAIIPTYAHDNDSAMDLSANEEVTLHPGERKLVGTGIAIELPPLTEAQIRPRSGLAYKQGITVLNTPGTIDEGYRGEIKVILINHGQEDFQIVKGMRIAQMAITPVLRPEIEVATTEILATTRGANGFGSTGV
>NC_019693.1|WP_015150905.1|6087832_6088030_-|DUF2442-domain-containing-protein
MMPYFIQTVTPEANYHLRLLYSNGTVIVIDFAPIIERGGVFSRLSDPAFFSQVKRSEAEDGRSIA
>NC_019693.1|WP_015150904.1|6087102_6087645_-|dCMP-deaminase-family-protein
MELEELRPTWDEYFIMLAKLAAMRSTCLAFPVGAVIVKNKQVVATGYNGSPSGTAHCTAQGYCYPGLSSCAESKSLPSRAVHAEANAIAQAAKHGISTEGSSIYVTLEPCLSCLKLIISAGIHEVFFETGFNSGNSLLVRDSFIQDGLVTLKQIHISEAIAQKAATFLMNPTSVATPSLI
>NC_019693.1|WP_015150903.1|6086512_6087049_+|P-loop-NTPase-family-protein
MIAQLESPTLDTPCRLPYAVEGLLQVFTSSHRNFFTSVMAQALRISGQGTPVLVVQFLKGGIGQGPEAPVQLGEHLDWVRCDLPRCIDTPELDEIEAGSLRKLWDYTQQVVSEGKYSLVVLDELSLAISFGLIPESEVLEFLEKRPSHVDIILTGPNMPEPILELADQITEIRRSHRP
>NC_019693.1|WP_044197796.1|6085659_6086247_-|adenylate-kinase
MRLVILGGPGAGKGTQASQLCSRLNIPCISTGEILFKAIAAQTELGRQAQPYAERGELVPDPIMIEFIREQLTQPYTQNGWLLDGYPRTSFQAEELDFLLESLQQTLDWAIWLNVSDAELMRRSLERSQAKPERGRPDDEPEFLRRRIQLFQERTTPILDYYNYGNRLLTLDGDRPPEEIQEEIWKTVNPNKNQA
>NC_019693.1|WP_015150914.1|6095873_6098918_-|phosphoenolpyruvate-carboxylase
MTVRLEPSNSVMTVSSSDLFLRHRLKVVEDLWESVLRTECGQELVVLLAQLRAMYSSEGQAYNFSESSVLKLVEQLDLNDAIRAARAFALYFQLINIVEQHYDQRDRLRGGAGPNTGVSENQQFDVPKESPYFASSQTVTRRRELANFSALFPKLKQLNVPPQQIQKIMESLDIRLVFTAHPTEIVRHTLRTKQRRLAQILQELDTLEEGRQPDSQTTSCETKDLIEALTEEIRLWWRTDELHQFKPSVLDEVDYTLHYFKEVLFDAVPQLHQRLKRSLQASFPYLQPPRYNFCKFGSWVGSDRDGNPYCTPSITWKTACYQRQLILDKYMGSLDRLSQLLSLSLHWSDVLPELLESLEQDRLQMPDIYEKLAIRYRQEPYRLKLAYICHRLENTRDRNQRLYTESDWNRHLSDIKNAPMYHSGSEFLDELRLIQRNLAATGLSCRDLEQLICQVEIYGFILAHLDIRQESSRHSTAITEIAEYLQILPRPYDDLSEAEKTEWLTTELKTRRPLIPGELPFSEQNSEIISTFRMLRALQEEFGLEICQTYIISMSRDVSDLLEVLLLAKEAGLYDPATGMGTIQVVPLFETVEDLKHAPTVIEDLFELPLYHALLSGGYQNALPVTATETTGAPNISNLKSSHIQVPKLQEVMLGYSDSNKDSGFLSSNWEIHKAQKALQLIGDRFGVVLRIFHGRGGSVGRGGGPAYEAILAQPGRSINGRIKITEQGEVLASKYTLPELALYNLETIASAVVQSSLLGSGFDDIEAWNQIMEELADCSRQHYRALIYEQPDFIDFFHEVTPIDEISKLQISSRPARRSSGKRDLGSLRAIPWVFSWTQTRFLLPAWYGVGTALNNFLEQEPEEHLKLLRYFYLKWPFFKMVISKVEMTLSKVDLEMAHHYVRELTQPENRDRFEALFTQIASEFNQTRDLVLAITEHQRLLDGDPDLQRSVQLRNATIVPLGLLQVSLLKRLREHQSQSVTGVIHSRYSKGELLRGALLTINGIAAGMRNTG
>NC_019693.1|WP_044195848.1|6099607_6099910_-|hypothetical-protein
MNLNLGTAEARSLAIALRGIQLGLGDSLMFLNPRDKTRVQRLLSCLYFNPYVNLLSNPGASASGFASTTDCMSGNLVDLSRQFSLGLEHGIQTQARFRSS
>NC_019693.1|WP_156824097.1|6099906_6100107_-|hypothetical-protein
MNPDANEPFVKISSELLITLLTPPFLGALLGGKAVSQMLQSMGQASEEVFRGDRLPVLNFPQAEED
>NC_019693.1|WP_156823953.1|6100523_6103820_+|hypothetical-protein
MQTNTGTTLTQWAAEALEVAGENIHLRFRGNTLHILWESESCPSMAIAVAKLTDALKKQGIDSLLPPDHPPIDEIFLYGRTLGTKRPDWSVRIESTHPHSPTPEDSPSSETGGPSCAELKPTQTPPTPPPPATENLPFSIADARMMLKVQSRASLGNPEAEALLAKGMARYLNETLSLYAISVKVLIRPLKRADRSQGDRPYPPRRLWIFCQSPNSPDATSLALPIAERLRELQLTGCSDAAILGRTTPDGKPELLLRVDLTPTVERLKNWARWGDIPAITRLLNQAVASRGLEVGVVQKDATLHLFCGNSTPEKDPTTDSPLAAADKSLCIDAIAPILNSLSPQGLHAVTLYGCRYGRQLDTPSNAPPLWVDWLDLPAARDPLLALSPRELATQGNLDALQFLLDRLVNPELDAKLNGNGLCVFLRQDPDLLHIMVEGSTCPEQDTLAPLVLEFLQELHLNGVEELRLYGRREGDKHPSWRYDTAIFYPSSLLSPEPELTLAAPEDPTPEPPEASAAELAEETPEPVIAFTHGDSDATEELPEAVESMFASDPPEELQACLSKQAIAPAPRERPSPGWVTRLCLLTGLFIPAKTFRRGPASSSKVAFIWGFLGLLVMLHTDWLLGHAALFSSSPTLETATVPGETPADPNPLPGTSPQQEFSFGELSRNPEANEEDPIFNGSSFTDFQEEQAIALNPETLPTFDYPTFNSQQLDEQLRLYLQYLATSGPPDVLIIGSSRALRGVAPMTIEESLSSRYPGLKVFNFGINGATAQVADFVVRELIPQEQLPKLILWADGARALNSGRSDRTFEAISRSPGYRHLLLGNRPRIPDMAKDDDASQSLSSLSETLVQRARTGLNIKENYETLDLWINEKLASVSANYEHRERLQGFLRGQLLLPLAETANHFIPEPARPSQEAIAETTTDSTFDSVEKSIIALQEESAALSNPDTLPPATLSNGFLPLSVRFNPLTYYEKHARVSGDYDADYESFQLAGIQTAAVTNLLEFTREHQIPLVFINMPLTQEYLDPVRLEYERQFQKYMLSLSLEKEGLSFRDLSQLWPTEIDRFSDPSHLNRYGAHEVSNRLSQDPMIPWPQTQ
>NC_019693.1|WP_015150917.1|6104279_6105770_-|hypothetical-protein
MTPPKVNAPNIHLFAFHLRHETSIRAEARIVPGAEKLWEKLGQILTQYGYETPLDLVGYYAPKGEQAYDPKEEGPGNIINLHKNGLIDFKGTLKLEGYPVNFTGIACPRRVFDSYALALNIRRPEKENERPTDAVPISIYGQFNTDGNLLLPDFIESSLGQTLLLTADLTDEQKQFSPEGLKNLACQCVEELIDDPKKRPSYSNKGRLFGSPIFEFGDIETLESQSDYRHILVLFFRDDTLKRKFESAYWDLIELFYYRNKILTSFDFTRSGYQETYRKYEEIEGIISDVNQQISNLVPNKRLGYKYLENLKQKLKIMPGLALEYSRLQQVLERNRNTIAIDAKKYDAALDEIQRKQNLDVFYLKPIDLSFVENFTRQEVPYFQERIKADLDYFVHGKGLVDRAIATIRGIVEIERIDRERHLETKLEAIAVGVGTAAVVAASSIYLSLDQPITSLNPPERSPSVALFVMVILISIAVGTIVFALFSWLLSWIRRD
>NC_019693.1|WP_015150919.1|6106324_6107860_-|C-3',4'-desaturase-CrtD
MSSHHQGKNKPRVIVIGAGIGGLTAGALLAKRGYSVRVFDLAIVPGGCASTFRRQGFTFDVGATQVAGLEPGGIHHRIFSELGINLPEATDCDPACAVFLPGETTPINIWRDPQRWQRERQRQFPGSEPFWQLMATLFRASWQFQGRDPVLPPRNLWDLWQLIKAFRPDTMVTVPFTLMTVGNALRGLGLHQDKRLKTFLDLQLKLYSQVNAQETALLYAATALGVSQSPQGLSHLKGSMQVLSDRLVEGLEKHGGELFMRHTVKQIQVTETGASTVTIFNQKTGEIWTEQPDLIVANVPVQNLVTLVELPKDSENLFQQLYRRRVENLPPASGAFVVYLGVKQEAIPENCPPHLQFLYDYEGEIGENNSLFVSVSRVGDGRSPEGMATITASSFTDTQIWADCEDYSRLKQQYETAAIARLGGYFALNAETIVYQESATPRTFARFTGRDRGIVGGVGQRVATFGPFGLATRTPIPHLWLVGDSTHPGEGTAGVSYSALTAVRQIEAEGY
>NC_019693.1|WP_015150920.1|6108165_6108492_-|STAS-domain-containing-protein
MNVIVKPQGNLDVKVSAMLQQKIAALVAENYNHYFIDLAGVKSLSHCGVSTLLAVARLVRKTGKRLSLCNLNSSVQYILEISDLACELDILESGCDDERLRVSPTILV
>NC_019693.1|WP_015150921.1|6108927_6110268_+|insulinase-family-protein
MTSTLVKFSSLPRLNCPKIHRLANGLTIIAEQMPVEAVNLSIWANVGSAVESDEINGMAHFLEHMVFKGTQRLESGEFERRIEERGAVTNAATSQDYTHYYITSAPQDFAELAPLQIDVVLNPSIPEDGFERERLVVLEEIRRSQDNPRRRIYSRAMETAFERLPYRRPVLGPTETIAGLKAQQMRDFHGTWYQPRTLTAVAVGNLPVEQLIGIVAEGFEKNGRPAFSLNPNWQLATDEEELIPEPSQVIGATPEPAFENIVRREFVDEKLQQARLVMMWRVPGLRELNKTYALDAIASILGRGRMGRLVQDLREEKGLVSGISVSNSSFHHQGVFTISAHLPSENLEVVEAAIQEHLRTFHQEVVRQSEIDRIVTQVVNRFVFSNETPSDRANLYGYYHSLIGDLEPAFNYPTHLQSLTPEDLQQAALDYLSADAYGLVTIKPAV
>NC_019693.1|WP_015150922.1|6110474_6111257_+|hypothetical-protein
MDASNLALKQLCRHLAGYQCELSEINHSLLIGAIDNGLLELDYYVDIDDEFYPEILELLAVPDFAPFLASLRLTAPDEGINGTRSWDLEPLIQGNGIYQNLKQLDIQGTQPEHHNRTILGNFAEDGIIARLLDKMPNLEQLSIPSAPSPTFFDRPAHPLKHLIIQTGYDTQNFIFNLAQSTCFSQLKTLDFTDYAETYIKDYEQHKTSKFHYLQLFNSQALPSLQTLIIKHSLLTEQDTPELQQSLLGTQLDLLRIIPGF
>NC_019693.1|WP_044197807.1|6111319_6114124_-|TIGR02921-family-PEP-CTERM-protein
MKGWLHSLFSAIFWLWNLTFLSTVYLGILPWLAIPLVQATIEGIIPLAFTLAVIGAIAIPTVCTLIGIKLRKQPLQLIRLFYGVEAPLFTLCLVRLFMLREMTAASNLVVGTALLALAAFALELFYGYAKGDRKLAWLQLATHSLMLLMGLYLGALLLFYVVPLTVWLTNSLISLDWIGAIIDIFRYSSWHAIWLVPFTFLFWGFSPTLFIAMPSALATFHIYSGYKIIQQFAQQYGRKWAVFGSGFVVTAWMVLFLAFQQQPQIHAFKYLENPPSTDRERQELLAKSDSIRQGLLNAYLLSYRYLSTHEDNNHIRAMYRDLLVEESAAQVLQNWYNGLMSPFLYQGSRSDIEKAATLYAELFDTPIQKGETKTILKAIQSTFNPEEAKAGLLNINEQRVLLAQQEITVTERGDWADVELYEVYENQTYQNEEVFYYFSLPESAVLTGVWLNETADRSDRYVFQISPRGAAQQVYNDQVRRNIDPALLEQVGPRQYRLRVFPVPARLSSWDNPNNQEQPKQHLWLTYKVMQSPQGWAMPQLAEKRNVFWTRQTQRQYHGETVKRLGDAWMPEFLPATDSPSGTTHQVTLPGDYQISAQPLTEKDYILPEGKRVGVIVDRSYSMRSHAKEVTETLNWLKRHGFADNRLENNDADIYLTASPGAIPLRQDNLSEVNPAQITYYGSLNYREMLQQFQELQGDTTYDAVALISDRGSYELAQDSPDLLTLSSPLWMVHLGGLPSAYDDGTLQAIQGTGGGVSTDLEEVLQRIATTAKLGPSTVSVVDGYRWVVEKPAKAALATLPQQLTRATVPDKAGLEPLGARQLILALSKQMDAASLADLDAIHAIAKHYEIVSPYSSAIVLVNEEQKRQLKEAESRSDRFDREIEDGTEDLQQPEDLMSVPVPEPHEWLGTIGAIGLLIFAKRKWGKIKSTRLT

Crispr_ID: NC_019693_66

• CRISPR_ID: NC_019693_66
• CRISPR_location: 6234891-6235861
• CRISPR_type: TypeI-D
• Repeat_type: V-U2:NA
• Spacer_info: 13 spacers
• Cas_protein_info: cas2,cas6,csc1gr5,csc2gr7,cas10d,cas3,WYL

Consensus repeat of NC_019693_66

Consensus_repeat	Method
GTTTCAATCCCGTTGCCGGGATTCATTGTAATGAAAG	CRISPRCasFinder
GTTTCAATCCCGTTGCCGGGATTCATT	CRT
GTTTCAATCCCGTTGCCGGGATTCATTGTACTGAAAG	PILER-CR

spacers of NC_019693_66

>66.1|6234928|36|NC_019693|CRISPRCasFinder
TCCCATGAGCATCACCAATATCCCAAGGATTAAATG
>66.2|6235001|39|NC_019693|CRISPRCasFinder
TCTGCTGATTCCCGCTATTACTCAGTCGGGGAAGACTAG
>66.3|6235077|35|NC_019693|CRISPRCasFinder,PILER-CR
TCATACAAAGCATCACTTATGTATTGTTCTGAAAA
>66.4|6235149|37|NC_019693|CRISPRCasFinder,PILER-CR
GAGGGCTTTTCAGGCTCCGTTTTGTGCGTGGCGATCG
>66.5|6235223|36|NC_019693|CRISPRCasFinder,PILER-CR
CAGCCCATTCTTTGGCTGTAAAGGGTATTTGGAGAA
>66.6|6235296|36|NC_019693|CRISPRCasFinder,PILER-CR
CTAAATAAACCAATCAGAGGGTTAATCATGACTTAT
>66.7|6235369|39|NC_019693|CRISPRCasFinder,PILER-CR
CGCTTGTTGCGTGGCGATCGCACCGTGCGATCGTTTGGT
>66.8|6235445|36|NC_019693|CRISPRCasFinder,PILER-CR
GAGCAATAAAAAGGAAGGGTGGTTAGTTCGTATTAA
>66.9|6235518|87|NC_019693|CRISPRCasFinder
CGATCGCTCCGTCGAATCTTTATCTGTTGCCGGGATTCATTGTACTGAAAGCTCAACCGGCCAAATCCTCACCGACTCGATTCAGTT
>66.10|6235642|38|NC_019693|CRISPRCasFinder
TCTATGCGGGGGAAATCTGGGAGGTGCTGAAACAGTGG
>66.11|6235717|37|NC_019693|CRISPRCasFinder
CTGGGCGACAATCAGCCGGATTATGGTTTAAGTGGCT
>66.12|6235791|34|NC_019693|CRISPRCasFinder
TTCACTTGTTCAACGTCAACGACTCACCCCGACT
>66.13|6234918|46|NC_019693|CRT
ATAATGAAAGTCCCATGAGCATCACCAATATCCCAAGGATTAAATG
>66.14|6234991|49|NC_019693|CRT
GTACTGAGAGTCTGCTGATTCCCGCTATTACTCAGTCGGGGAAGACTAG
>66.15|6235067|45|NC_019693|CRT
GTAATGAAAGTCATACAAAGCATCACTTATGTATTGTTCTGAAAA
>66.16|6235139|47|NC_019693|CRT
CTAATGAAAGGAGGGCTTTTCAGGCTCCGTTTTGTGCGTGGCGATCG
>66.17|6235213|46|NC_019693|CRT
GTACTGAAAGCAGCCCATTCTTTGGCTGTAAAGGGTATTTGGAGAA
>66.18|6235286|46|NC_019693|CRT
GTACTGAAAGCTAAATAAACCAATCAGAGGGTTAATCATGACTTAT
>66.19|6235359|49|NC_019693|CRT
GTACTGAAAGCGCTTGTTGCGTGGCGATCGCACCGTGCGATCGTTTGGT
>66.20|6235435|46|NC_019693|CRT
GTACTGAAAGGAGCAATAAAAAGGAAGGGTGGTTAGTTCGTATTAA
>66.21|6235508|24|NC_019693|CRT
GTACTGAAAGCGATCGCTCCGTCG
>66.22|6235559|46|NC_019693|CRT
GTACTGAAAGCTCAACCGGCCAAATCCTCACCGACTCGATTCAGTT
>66.23|6235632|48|NC_019693|CRT
GTACTGAAAGTCTATGCGGGGGAAATCTGGGAGGTGCTGAAACAGTGG
>66.24|6235707|47|NC_019693|CRT
GTACTGAAAGCTGGGCGACAATCAGCCGGATTATGGTTTAAGTGGCT
>66.25|6235781|44|NC_019693|CRT
GTACTGAAAGTTCACTTGTTCAACGTCAACGACTCACCCCGACT
>66.26|6235518|25|NC_019693|PILER-CR
CGATCGCTCCGTCGAATCTTTATCT
>66.27|6235580|36|NC_019693|PILER-CR
CTCAACCGGCCAAATCCTCACCGACTCGATTCAGTT
>66.28|6235653|38|NC_019693|PILER-CR
TCTATGCGGGGGAAATCTGGGAGGTGCTGAAACAGTGG
>66.29|6235728|37|NC_019693|PILER-CR
CTGGGCGACAATCAGCCGGATTATGGTTTAAGTGGCT
>66.30|6235802|34|NC_019693|PILER-CR
TTCACTTGTTCAACGTCAACGACTCACCCCGACT

CRISPR arrays and Neighbor proteins around NC_019693_66

CRISPR arrays

The CRISPR arrays of NC_019693_66

>merge|NC_019693|66|6234891-6235861|CRISPRCasFinder,CRT,PILER-CR
GTTTCAATCCCGTTGCCGGGATTCATTATAATGAAAGTCCCATGAGCATCACCAATATCCCAAGGATTAAATGGTTTCAATCCCGCTGCCGGGATTCATTGTACTGAGAGTCTGCTGATTCCCGCTATTACTCAGTCGGGGAAGACTAGGTTTCAATCCCGTTGCCGGGATTCATTGTAATGAAAGTCATACAAAGCATCACTTATGTATTGTTCTGAAAAGTTTCAATCCCGTTGCCGGGATTCATTCTAATGAAAGGAGGGCTTTTCAGGCTCCGTTTTGTGCGTGGCGATCGGTTTTAATCCCGTTGCCGGGATTCATTGTACTGAAAGCAGCCCATTCTTTGGCTGTAAAGGGTATTTGGAGAAGTTTCAATCCCGTTGCCGGGATTCATTGTACTGAAAGCTAAATAAACCAATCAGAGGGTTAATCATGACTTATGTTTCAATCCCGTTGCTGGGATTCATTGTACTGAAAGCGCTTGTTGCGTGGCGATCGCACCGTGCGATCGTTTGGTGTTTCAATCCCGTTGCCGGGATTCATTGTACTGAAAGGAGCAATAAAAAGGAAGGGTGGTTAGTTCGTATTAAGTTTCAATCCCGTTGCCGGGATTCATTGTACTGAAAGCGATCGCTCCGTCGAATCTTTATCTGTTGCCGGGATTCATTGTACTGAAAGCTCAACCGGCCAAATCCTCACCGACTCGATTCAGTTGTTTCAATCCCGTTGCCGGGATTCATTGTACTGAAAGTCTATGCGGGGGAAATCTGGGAGGTGCTGAAACAGTGGGTTTCAATCCCGTTGCCGGGATTCATTGTACTGAAAGCTGGGCGACAATCAGCCGGATTATGGTTTAAGTGGCTGTTTCCATCCCGTTGCCGGGATTCATTGTACTGAAAGTTCACTTGTTCAACGTCAACGACTCACCCCGACTGTTTCAATCCCGTTGCCGGGATTCATTGTACTGAAAG

>NC_019693|66|64|6234891-6235861|CRISPRCasFinder
GTTTCAATCCCGTTGCCGGGATTCATTATAATGAAAG	TCCCATGAGCATCACCAATATCCCAAGGATTAAATG
GTTTCAATCCCGCTGCCGGGATTCATTGTACTGAGAG	TCTGCTGATTCCCGCTATTACTCAGTCGGGGAAGACTAG
GTTTCAATCCCGTTGCCGGGATTCATTGTAATGAAAG	TCATACAAAGCATCACTTATGTATTGTTCTGAAAA
GTTTCAATCCCGTTGCCGGGATTCATTCTAATGAAAG	GAGGGCTTTTCAGGCTCCGTTTTGTGCGTGGCGATCG
GTTTTAATCCCGTTGCCGGGATTCATTGTACTGAAAG	CAGCCCATTCTTTGGCTGTAAAGGGTATTTGGAGAA
GTTTCAATCCCGTTGCCGGGATTCATTGTACTGAAAG	CTAAATAAACCAATCAGAGGGTTAATCATGACTTAT
GTTTCAATCCCGTTGCTGGGATTCATTGTACTGAAAG	CGCTTGTTGCGTGGCGATCGCACCGTGCGATCGTTTGGT
GTTTCAATCCCGTTGCCGGGATTCATTGTACTGAAAG	GAGCAATAAAAAGGAAGGGTGGTTAGTTCGTATTAA
GTTTCAATCCCGTTGCCGGGATTCATTGTACTGAAAG	CGATCGCTCCGTCGAATCTTTATCTGTTGCCGGGATTCATTGTACTGAAAGCTCAACCGGCCAAATCCTCACCGACTCGATTCAGTT
GTTTCAATCCCGTTGCCGGGATTCATTGTACTGAAAG	TCTATGCGGGGGAAATCTGGGAGGTGCTGAAACAGTGG
GTTTCAATCCCGTTGCCGGGATTCATTGTACTGAAAG	CTGGGCGACAATCAGCCGGATTATGGTTTAAGTGGCT
GTTTCCATCCCGTTGCCGGGATTCATTGTACTGAAAG	TTCACTTGTTCAACGTCAACGACTCACCCCGACT
GTTTCAATCCCGTTGCCGGGATTCATTGTACTGAAAG

>NC_019693|66|6|6234891-6235851|CRT
GTTTCAATCCCGTTGCCGGGATTCATT	ATAATGAAAGTCCCATGAGCATCACCAATATCCCAAGGATTAAATG
GTTTCAATCCCGCTGCCGGGATTCATT	GTACTGAGAGTCTGCTGATTCCCGCTATTACTCAGTCGGGGAAGACTAG
GTTTCAATCCCGTTGCCGGGATTCATT	GTAATGAAAGTCATACAAAGCATCACTTATGTATTGTTCTGAAAA
GTTTCAATCCCGTTGCCGGGATTCATT	CTAATGAAAGGAGGGCTTTTCAGGCTCCGTTTTGTGCGTGGCGATCG
GTTTTAATCCCGTTGCCGGGATTCATT	GTACTGAAAGCAGCCCATTCTTTGGCTGTAAAGGGTATTTGGAGAA
GTTTCAATCCCGTTGCCGGGATTCATT	GTACTGAAAGCTAAATAAACCAATCAGAGGGTTAATCATGACTTAT
GTTTCAATCCCGTTGCTGGGATTCATT	GTACTGAAAGCGCTTGTTGCGTGGCGATCGCACCGTGCGATCGTTTGGT
GTTTCAATCCCGTTGCCGGGATTCATT	GTACTGAAAGGAGCAATAAAAAGGAAGGGTGGTTAGTTCGTATTAA
GTTTCAATCCCGTTGCCGGGATTCATT	GTACTGAAAGCGATCGCTCCGTCG
AATCTTTATCTGTTGCCGGGATTCATT	GTACTGAAAGCTCAACCGGCCAAATCCTCACCGACTCGATTCAGTT
GTTTCAATCCCGTTGCCGGGATTCATT	GTACTGAAAGTCTATGCGGGGGAAATCTGGGAGGTGCTGAAACAGTGG
GTTTCAATCCCGTTGCCGGGATTCATT	GTACTGAAAGCTGGGCGACAATCAGCCGGATTATGGTTTAAGTGGCT
GTTTCCATCCCGTTGCCGGGATTCATT	GTACTGAAAGTTCACTTGTTCAACGTCAACGACTCACCCCGACT
GTTTCAATCCCGTTGCCGGGATTCATT

>NC_019693|66|7|6235040-6235861|PILER-CR
GTTTCAATCCCGTTGCCGGGATTCATTGTAATGAAAG	TCATACAAAGCATCACTTATGTATTGTTCTGAAAA
GTTTCAATCCCGTTGCCGGGATTCATTCTAATGAAAG	GAGGGCTTTTCAGGCTCCGTTTTGTGCGTGGCGATCG
GTTTTAATCCCGTTGCCGGGATTCATTGTACTGAAAG	CAGCCCATTCTTTGGCTGTAAAGGGTATTTGGAGAA
GTTTCAATCCCGTTGCCGGGATTCATTGTACTGAAAG	CTAAATAAACCAATCAGAGGGTTAATCATGACTTAT
GTTTCAATCCCGTTGCTGGGATTCATTGTACTGAAAG	CGCTTGTTGCGTGGCGATCGCACCGTGCGATCGTTTGGT
GTTTCAATCCCGTTGCCGGGATTCATTGTACTGAAAG	GAGCAATAAAAAGGAAGGGTGGTTAGTTCGTATTAA
GTTTCAATCCCGTTGCCGGGATTCATTGTACTGAAAG	CGATCGCTCCGTCGAATCTTTATCT
GTTGCCGGGATTCATTGTACTGAAAGCTCAACCGGCC	AAATCCTCACCGACTCGATTCAGTTGTTTCAATCCC
GTTGCCGGGATTCATTGTACTGAAAGTCTATGCGGGG	GAAATCTGGGAGGTGCTGAAACAGTGGGTTTCAATCCC
GTTGCCGGGATTCATTGTACTGAAAGCTGGGCGACAA	TCAGCCGGATTATGGTTTAAGTGGCTGTTTCCATCCC
GTTGCCGGGATTCATTGTACTGAAAGTTCACTTGTTC	AACGTCAACGACTCACCCCGACTGTTTCAATCCC
GTTGCCGGGATTCATTGTACTGAAAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015151023.1|6239369_6240182_-|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl|CDD|337605
NC_019693.1|WP_015151011.1|6224880_6226197_-|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl|CDD|224938
NC_019693.1|WP_015151026.1|6242198_6245162_-|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	cas10d	cd09712_cas10d_CAS-I-D	gnl|CDD|187843
NC_019693.1|WP_015151027.1|6245455_6247525_-|type-I-D-CRISPR-associated-helicase-Cas3'	cas3	cd09710_cas3_CAS-I-D	gnl|CDD|187841
NC_019693.1|WP_156823957.1|6223466_6223664_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151013.1|6227642_6228641_+|ketoacyl-ACP-synthase-III	unknown	unknown	gnl|CDD|236475
NC_019693.1|WP_015151018.1|6233122_6233359_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151017.1|6231852_6232488_-|LAGLIDADG-DNA-endonuclease-family	unknown	unknown	gnl|CDD|367365
NC_019693.1|WP_015151022.1|6238807_6239155_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NC_019693.1|WP_015151028.1|6249510_6249789_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151029.1|6250266_6251220_+|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl|CDD|379100
NC_019693.1|WP_015151025.1|6241104_6242091_-|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	gnl|CDD|375747
NC_019693.1|WP_015151015.1|6230002_6230641_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
NC_019693.1|WP_015151019.1|6233750_6234689_+|ParA-family-protein	unknown	unknown	gnl|CDD|224113
NC_019693.1|WP_015147653.1|6247617_6249195_-|IS1182-family-transposase	unknown	unknown	gnl|CDD|372705
NC_019693.1|WP_015151014.1|6228818_6229700_+|ACP-S-malonyltransferase	unknown	unknown	gnl|CDD|223408
NC_019693.1|WP_015151030.1|6253570_6254053_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl|CDD|376811
NC_019693.1|WP_015151016.1|6231056_6231668_-|YdcF-family-protein	unknown	unknown	gnl|CDD|99750
NC_019693.1|WP_015151024.1|6240171_6240942_-|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	gnl|CDD|274458
NC_019693.1|WP_015151012.1|6226463_6227531_+|phosphate-acyltransferase-PlsX	unknown	unknown	gnl|CDD|235414

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_015151023.1|6239369_6240182_-|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	1.2e-22	75.5	0.0
NC_019693.1|WP_015151029.1|6250266_6251220_+|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	4.6e-21	70.3	4.7
NC_019693.1|WP_015151025.1|6241104_6242091_-|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	6.3e-75	246.8	0.0
NC_019693.1|WP_015151026.1|6242198_6245162_-|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	cas10d	cd09712_cas10d_CAS-I-D	2.6e-205	678.8	0.0
NC_019693.1|WP_015151027.1|6245455_6247525_-|type-I-D-CRISPR-associated-helicase-Cas3'	cas3	cd09710_cas3_CAS-I-D	4e-59	195.1	0.0
NC_019693.1|WP_015151024.1|6240171_6240942_-|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	7.6e-54	177.1	0.2
NC_019693.1|WP_015151022.1|6238807_6239155_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1.5e-20	68.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015151023.1|6239369_6240182_-|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|337605	pfam10040, CRISPR_Cas6, CRISPR-associated endoribonuclease Cas6. Cas6 is a member of the RAMP (repeat-associated mysterious protein) superfamily. It is among the most widely distributed Cas proteins and is found in both bacteria and archaea. Cas6 functions in the generation of CRISPR-derived guide RNAs for invader defense in prokaryotes.	2.16129e-13
NC_019693.1|WP_015151011.1|6224880_6226197_-|D-alanyl-D-alanine-carboxypeptidase	gnl|CDD|224938	COG2027, DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Cell envelope biogenesis, outer membrane].	1.18145e-55
NC_019693.1|WP_015151026.1|6242198_6245162_-|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	gnl|CDD|187843	cd09712, Cas10d_I-D, CRISPR/Cas system-associated protein Cas10d. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain. Fused to N-terminal HD domain; signature gene for I-D subtype; also known as Csc3 family.	0
NC_019693.1|WP_015151027.1|6245455_6247525_-|type-I-D-CRISPR-associated-helicase-Cas3'	gnl|CDD|187841	cd09710, Cas3_I-D, CRISPR/Cas system-associated protein Cas3; Distinct diverged subfamily of Cas3 helicase domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Diverged DNA helicase Cas3'; signature gene for Type I and subtype I-D.	5.03643e-55
NC_019693.1|WP_015151019.1|6233750_6234689_+|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	5.68206e-52
NC_019693.1|WP_015151024.1|6240171_6240942_-|type-I-D-CRISPR-associated-protein-Cas5/Csc1	gnl|CDD|274458	TIGR03159, cas_Csc1, CRISPR type I-D/CYANO-associated protein Csc1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family is a CRISPR-associated (Cas) family strictly associated with the Cyano subtype of CRISPR/Cas locus, found in several species of Cyanobacteria and several archaeal species. This family is designated Csc1 for CRISPR/Cas Subtype Cyano protein 1, as it is often the first gene upstream of the core cas genes, cas3-cas4-cas1-cas2.	1.17237e-55
NC_019693.1|WP_015151017.1|6231852_6232488_-|LAGLIDADG-DNA-endonuclease-family	gnl|CDD|367365	pfam03161, LAGLIDADG_2, LAGLIDADG DNA endonuclease family. This is a family of site-specific DNA endonucleases encoded by DNA mobile elements. Similar to pfam00961, the members of this family are also LAGLIDADG endonucleases.	3.28638e-44
NC_019693.1|WP_015151022.1|6238807_6239155_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.13602e-21
NC_019693.1|WP_015151029.1|6250266_6251220_+|WYL-domain-containing-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	1.1678e-21
NC_019693.1|WP_015151025.1|6241104_6242091_-|type-I-D-CRISPR-associated-protein-Cas7/Csc2	gnl|CDD|375747	pfam18320, Csc2, Csc2 Crispr. The Csc2 Crispr family of proteins forms a core RNA recognition motif-like domain, flanked by three peripheral insertion domains: a lid domain, a Zinc-binding domain and a helical domain. The CRISPR-Cas system is possibly a mechanism of defence against invading pathogens and plasmids that functions analogously to the RNA interference (RNAi) systems in eukaryotes.	0
NC_019693.1|WP_015151015.1|6230002_6230641_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	3.7639e-47
NC_019693.1|WP_015147653.1|6247617_6249195_-|IS1182-family-transposase	gnl|CDD|372705	pfam13751, DDE_Tnp_1_6, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	8.15327e-14
NC_019693.1|WP_015151014.1|6228818_6229700_+|ACP-S-malonyltransferase	gnl|CDD|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	3.34441e-101
NC_019693.1|WP_015151030.1|6253570_6254053_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl|CDD|376811	pfam02542, YgbB, YgbB family. The ygbB protein is a putative enzyme of deoxy-xylulose pathway (terpenoid biosynthesis).	4.72048e-98
NC_019693.1|WP_015151016.1|6231056_6231668_-|YdcF-family-protein	gnl|CDD|99750	cd06259, YdcF-like, YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been idenitified. The family also includes Escherichia coli sanA and Salmonella typhimurium sfiX, which are involved in vancomycin resistance; sfiX may also be involved in murein synthesis.	2.6213e-20
NC_019693.1|WP_015151013.1|6227642_6228641_+|ketoacyl-ACP-synthase-III	gnl|CDD|236475	PRK09352, PRK09352, beta-ketoacyl-ACP synthase 3.	2.16166e-171
NC_019693.1|WP_015151012.1|6226463_6227531_+|phosphate-acyltransferase-PlsX	gnl|CDD|235414	PRK05331, PRK05331, phosphate acyltransferase PlsX.	1.12754e-170

Protein sequences

>NC_019693.1|WP_015151019.1|6233750_6234689_+|ParA-family-protein
MAYIISTINMKGGVGKTTLTVNLAACLAKDYQKRVLVVDLDTQISATLSLVSPHDFSKLRKEKRTLKHLVNDFIQPIDQKSLPIQDIIKPYIGNVKGLDLLPGDLEIYDDFMVSEVLHRKALRLGKDNFEEVWTKLEQILVRGILDPVMKDYDFIILDCAPGYNLLTRSALVASDYYLLPAKPEPLSLIGIQLLERRINQLREVYKNENPLDLDMVGIVFSMSGNVLTGRYYRQVMRRVHDDFGETKIFKTRIPMDVNVSKAVDSFLPVFLTHPTSIGAKAFSQLTDEFMQKLQIIVEMKEQRNKLNLVNLD
>NC_019693.1|WP_015151018.1|6233122_6233359_+|hypothetical-protein
MIRIRDIVQQALAMGYLTVEAEDQLRDLLSAQYDLEDLNAFMTLQHASMSGRIKQQSRLLRYKTTGEDRINQVSRQAG
>NC_019693.1|WP_015151017.1|6231852_6232488_-|LAGLIDADG-DNA-endonuclease-family
MDFNVASKVEQRGVLVGMLLGQGKRNQNNFYISHRATQENYVLFKKQLLEQITQQPVSIRPRTTNRGEQLLCLEPKLIPLTRVLVKKLYCGGIKTVTPKFLNLLTPAGIALWFLDRGSKSLKKRQGKIHALEVYLNTNLSESENEIIIDYFSEIWGFKWGMSKTADAYRLRMGTQEGKRFLSFITPYVPDSLRYKVQTSSNVTATTYGPQV
>NC_019693.1|WP_015151016.1|6231056_6231668_-|YdcF-family-protein
MLLKICLKGRLHGSAKTKQSPGRSLVWLLLGLSLIGAIAYKQIRNYIDTPQALLVLGGALEREEFAAEFARKNPHLQVWVSGGSNQEYAEWVFSKAGIDLERVHLDYQAQDTVTNFTTLVDQLKSEGIASVYLITSDDHMRRAQVIGEIVLGSRGISFKPLPVPSGRSPEPIEKAIRDGARAILWVTTGHTGARFAPVQGEED
>NC_019693.1|WP_015151015.1|6230002_6230641_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MEKTREPVASLILYNLLKWSVVSPMLHTYFRGRIYGALNVPMSGPLVVVSNHASDYDPPILSNCMNRPVAFMAKEELFEVPVLRQTISLYGAYPVRRGESDRAAMRAALSSLEAGWATGLFLDGTRSPDGRIHNPKLGAALIAAKAKVPILPVSLWGTQAIVKKGSIVPKPVPVTIRIGEAIPAPSSTKREVLEAITQHCVEVIHGLHDLGR
>NC_019693.1|WP_015151014.1|6228818_6229700_+|ACP-S-malonyltransferase
MTKTAWVFPGQGSQALGMGVDVANLPIAQEKYAAAETILGWSVLDICTNAEDKLTSSLYTQPSLYVVESILVDLMRDRHQQPDLVAGHSLGEYVALYAAGVFDFAAGLQLVKYRAELMNTVAGGQMTALIGFNREQLDAQISATPDVVLANDNSDGQVVISGTPEAVESVIAAIKVKRAVKLNVAGAYHSPFMEPAQAEFQKALDAVPFTDAIVPVLSNTDPTPETKAEALKQRLSRQMTGSVRWREIMLQLPQEGIESVIEIGPGKVLANLIKRACSDLAVTNVSTAADLPA
>NC_019693.1|WP_015151013.1|6227642_6228641_+|ketoacyl-ACP-synthase-III
MKEIGVGIAITGSGSATPANVLDNQALCQMVETSEEWIESRTGIQTRRVASGEESLTELATQAAFKAVAMSGLQPTDLDLIVLATSTADDLFGSASKIQANLGATRAVAFDLTAACSGFLFGFVTAAQFIRTGVYKNVLVIGADLLSRWVDWGDRRTCILFGDGAGAVVMQANTTRDRLLGFELCSDGSQNDCLTLAFQPQEKALTPNLSVGQGTYQFIQMNGKEVYRFAVKRVPEVIEKALYRADIEVDRVDWLLLHQANQRILDAVAVRLKIPTHKVLGNLANYGNTSAASIPIALDEAVREGKIKPGDVIAAAGFGAGLTWGSAIFEWG
>NC_019693.1|WP_015151012.1|6226463_6227531_+|phosphate-acyltransferase-PlsX
MGSSRARIAIDAMGGDNAPAAIVTGALQAASELDVDVLLVGDPDKIDSCIKEHQKDANFPNPNQVEIIPADEVVEMHEEPLSALKRKRNASIRVAMELVKKNQAQAIVSAGHSGAAMAAALLHLGRLRGIDRPAIGAIFPTIVPNKSVLILDVGANVDCRPKFLEQFAVMGTIYSQYVLGVEEPRVGLLNIGEEPSKGNDQAVRTHQMLVDNPLVPFFGNAEGRDILSGNFDVIVCDGFAGNVVLKFAEGLGEIVLNILKEELTQGIMGKMGVTLLKPSLKRFKQRVDHVERGGGLLLGVAGICIITHGSSQGPTVYNAIRLAKDAIDHNVLDRMQSQFESPKQLTAVPEPTAES
>NC_019693.1|WP_015151011.1|6224880_6226197_-|D-alanyl-D-alanine-carboxypeptidase
MLDLLSSGLLSVWLDMTGLKLPRENAVELVLGPAIPGYILAEIADPPTEQQVQQYLQGLVAKGLQTEGQGVWVQSSHQLLANHQGTVPLPAASITKVATSLAALLTWDIDHQFEILIGTQGKIVDGVLQGDLIVTGGDDPFFIWEEAIVLGNTLNQMGIRQVTGNLMITGNFSMNFYENPQVSAEMLREALDERLWTHEANHAYWQMAPGTPKPQVAIAGQIAIANQPIPNQTLLIRHRSLPLRELLQQMNIYSNNVMAQMLADALGGVNQVRNLSAKAAGVPLSEIQLINGSGLGRENQISPRAACGMFMALQQLLQPKNLSLSDLFPVAGRDGGTMDYRQIPGGAVVKTGTLWDVSALAGILPTQDKGWICFAILNRGNYLDGFRQEQDKLLQQFLQTWHTTLMPPSQIHNLFTGYSSQGHVDAVKRNEILFEYGG
>NC_019693.1|WP_156823957.1|6223466_6223664_-|hypothetical-protein
MSSFTIAFIGITPLGNLISGFVADRLGVVTTLTIKGLIGLVATGIFSPQSQPIHRSLKHWVNCGN
>NC_019693.1|WP_015151022.1|6238807_6239155_-|CRISPR-associated-endonuclease-Cas2
MGVTRQSHVTRVHAFLYLVVYDLPATKAGNKRRQRLHDLLFGYGNWKQYSLFECFLSTKQFVTLQHKIEDLIKPAEELLCIYILDSTGIQRTIVYGTQQFSLWQKTVQVPLRPVW
>NC_019693.1|WP_015151023.1|6239369_6240182_-|CRISPR-associated-endoribonuclease-Cas6
MSDNLDGLYSLVVELRAIESGNPPATLGRALHALVLNWLNLANPELATATHDLAVSPFSVSGLIGNRRPNEVKGGDCFHLKIGVLDSQLIQPLLTGLTQWAMQPIILAKFPFLMTRTYMIHESHPLANVSSYSKLVEAAGNQSLIELTFLSPTSFKQKQGIQTFPLPELVFGNLQRRWNNFAPEPLHFPEIEWQGLVSAYELKTHALKLEGGAEIGAQGWIRYRFSDPEQAKIARILAEFAFYAGVGRKTTMGMGQTQFNSSTKPKPIKR
>NC_019693.1|WP_015151024.1|6240171_6240942_-|type-I-D-CRISPR-associated-protein-Cas5/Csc1
MVLYYCRLKLHDNVFFATREMGILYETEKYLHNWALTYAIFSGSYLPHPYHSQPAQQPGYLDPKNEQNLFFLNPEKIYVFPALPLRCFYQVNTFKAAQTTYYGKSKQFGEKGANRNYPINYGRAKELAVGSEYATYLFAPEPLYIPQWIRLGKWMAKVHLTKYPIPKTAMQAKTGEYACPHPLNPLDLPSQQQIMLYNRIVMPPVSLITESQLVGEYWELSGDDWDSFRANLPELPKKVCLPRGIIYGAGVTADVR
>NC_019693.1|WP_015151025.1|6241104_6242091_-|type-I-D-CRISPR-associated-protein-Cas7/Csc2
MSQLEKIQSSFSKQFPRLAGGRYVQFLMLRHSQSFPVFQTDGVLNTARTQAGIESPEMMSRLVMFKRKQTTPERLTGRELLRSLGITSGEIDAPNYCEYNGEKSCKKCPDCILYGFAIGDSGSERSKVYSDSAFSLTAYEQSHRSFTFNAPFEGGTMSEGGKMRSAINELDHVIPEVTFPTVETLRDSTYEGFLYVLGNLIRTRRYGAQESRTGTVKNHLLGIVISDGEIFSNLHFTQALYDALKGDTTAAIADIKAQATTVIHTLLAEEPVRIYQTITGEPLKTLLDEVLAIYQNEAALTPIISTLATQTQTYSETYGAESNKKKKR
>NC_019693.1|WP_015151026.1|6242198_6245162_-|type-I-D-CRISPR-associated-protein-Cas10d/Csc3
MASLLQNVIKITLDPDTDPILAQYIDLVLPAVEREFSSISALGGDYETHYQQLKQRGDNHAVEKAQRWSDRPDQNLCVHVLNALLIAWNLAENYLNSPLSDEEKRLLCLGITLHDYNKYCHGQGEEAPKAYEVPEILSLCQEMGRRLNFQAFWPEWESYLSDIGFLAQNTQFKVGTNPYPSNWPKFAIAHSGRLTCPLRHLLAFADIAVHLKDAADIKKDPENINPEKGGKRLREHLRDLNIKKTLVYHHLRDTIGILTNRIHDATLNFAAEQDWQPLIFFARGVVYLAPLKPEPPNREELQEFVWQQISQVLSQKMLEGDIGFKRDGKGLKVAPQTSELFTPEDLIRQLPPVIEVRVNNPNNLATPKRLDKLVTEKKLTPEEREYLSRGEDLRSDRLAEFLIVVQREFLADCPDYVDWILEALKLKDCLTLEQIQITIGGVNYGWYRAAAHYFCQHGTLDGEQTLELLTDLANRLATWATENQLLPQYRSPTREIFNQYLERYLDIAGWETIVPPFEAELATYSFAKTRKGKQPICSLSSGEFASEDQMDSVVLFKPQQYSNKNALGGGQIKRGISKIWSLEMLLRQALWSVRSGKLEEQQPVFLYIFPAYVYAPQIIRAIRGLMVELQSVSLWKIREHWLKCGMDVSRLSELDWLSEDRDIGEKARQVYDTKDLPFMATTHTTTLGKTVTDAWVYLAFLALVLPKLLGVRVVATSSNVPLYSSDREFVGSAVLDGAAGFWSLLQCPPSVRTEQLDRILMRLLIVYSLHLDNRSNPPDARWGALNGTVRDVMTDILNIFAIAQEGLRSHKRDYPSSEEVARYWQFAQIWSQLDKTMVEKLNLITQLVQQYRTFYQVNITDSSHAILLPISKALETILSVPTQVDQEDLILQGAGLLKDAIDRQPAYTRPLLMDKSLDIAIRQQRELEAIYQFMETCVRDLFGTLYRGDRALLQENRNRIKSGAEFAYRWLALQEKNQKNLDSKTRS
>NC_019693.1|WP_015151027.1|6245455_6247525_-|type-I-D-CRISPR-associated-helicase-Cas3'
MKLNLKPLYSQLNPGVGHCPLKCQDRCLVQERAPTLKPPPGYTCPLSSHQAETYQAVVEGDADIIFNKSATGDGKTLSGALPSLLDEGFRLMALYPTIELVEDQTQQQRGYHQLFGLDADSRIDRLFGEELNRRVQDESSNKFQELLRAIYHKPILLTNPDIFHFITHYRYRQSAFDPSLLPLALAEWPDLWMFDEFHIFGPHQEAAALNSLTLIRRTQQDKRPRRFLFTSATPKRDFIAQLQQAEFKVREISGRYTSEETPGYRQILQAISLEFVELGEGDAVQWLVESADQLRIALPPGGRGLIILNSIAAVNRVVRKLADALPGVRVREISGRIDRRLRSQIQGELKDSQDPVLIVATSAVDVGVDFRIHLLICEGSDAATVVQRLGRLGRHPGFAEYRAFVLVSRRTPWVIPRLQQAIAGEDTLDRTQFHEAIAEAFEPPKAFEEYRQHWGALQAQGMMVTMSQENAQVSQSIRDRMTEDLNRVYPNRLESARRQWFAMMGNPVGKATQEELLRFRGGTALQAAVWDDGRFYTYDLLRLLPYAKVELCDRETFLTAATAAGYGTESFPEAYIQVYLRVQEWVEKRISLTLSTSRDTDELHAGELCLLDRLMTVGHPQEQVKRCLQRRKFLAFLVPVNRTQPSSHWQVADKLQLPPTFGLYRLTDAGGRTYACAFNQDALLLEASK
>NC_019693.1|WP_015147653.1|6247617_6249195_-|IS1182-family-transposase
MRPPLWHPPVELSDSEQVIINRIKKAKLFTFLRLNRLFIFDDEFQEELNTIFKDSTMGNCPVAPAQLALATILQAYMGISDEEVIEELVMDLRWQLALNCLNCEKPPFSKATLIRFRSALIKKGFDQRLIDRTVDIAKLKGGFGSANLRAALDSSPLWGAGKVEDTYNLLGHALRKALSIIASQQGWGLAEIANEAGADFVNSSSLKAALDLNWDDPAESQKALSTILKSLNSVEEWIQQQSNPDEIEEAQAPLQVARLIESQNVTLDTMGVPKLAKGVAKDRRISIEDPDMRHGRKSRSQKINGYKRHILKDLDIGVIRAVAVTRANTPEAAATVDLEVDLKRQQVQLNELHIDRAYLSSHWVKERSEQLQIFCKAWPVRNSGRFDKNAFVFDWDNQVISCPNQVIMPFEPGKIVHFPKPECAACPLRERCTTSKNGRSISIHPDEGLMQELRQRQSTSSGRAQLRERTSVEHSLAHVGQWQDKRARYIGQRKNLFDLRRVAVVHNLHVIARMNEVLPIQQAAL
>NC_019693.1|WP_015151028.1|6249510_6249789_-|hypothetical-protein
MIKINHSRQSKNSQAPQTLPLLKPGSLGWVNPQINENLLKSDSLTTKQVEERFGIPATNLRCCHINYVLPWKTYLIFHQGRDRWKIYTEAAV
>NC_019693.1|WP_015151029.1|6250266_6251220_+|WYL-domain-containing-protein
MPVRYSHIALALHILELLAERDRDRNEILDLVGEFLYENNSSIEDVKQKFDRTLRELRDWGFKIDHRPYSLVESNFPIILSASQRHTLYRAAHFLTEMNFATEAQQLVRLSQLGESDSPPDIQVDFAPPTNYSAPQCRRLLEQLQDRCAQKYRFTLRYIDSQKQELTMDLDRCELRLHDGTLYLFAFVPDLEQYHRNLRPELVYRNWLFRVDRIKSVGPPSTQAWVYSSFPTLTIRYRMTGPLANYVPRRIHEQVIERNLKQKYVEIETQEDYPFWFRQRILRYGSNARVIDPPWIVEEIATILRKAASNYDDIPGP
>NC_019693.1|WP_015151030.1|6253570_6254053_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MNIRIGNGYDIHQLVSDRPLILGGIRIPHELGLLGHSDADVLTHAIMDAMLGALSLGDIGLYFPPSDPQWAGADSLKLLAQVHQLILERGWEVGNIDSVVVAERPKLKPHISAMRDRLAQVLNIEGDRIGIKATTNEKLGPVGREEGIAAYAVTLLVTQP

Crispr_ID: NC_019693_67

• CRISPR_ID: NC_019693_67
• CRISPR_location: 6251489-6253282
• CRISPR_type: TypeI-D
• Repeat_type: V-U2
• Spacer_info: 24 spacers
• Cas_protein_info: WYL,cas3,cas10d,csc2gr7,csc1gr5,cas6,cas2

Consensus repeat of NC_019693_67

Consensus_repeat	Method
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	PILER-CR
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CRISPRCasFinder
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CRT

spacers of NC_019693_67

>67.1|6251526|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ATCGTTGAGGTGAAGGGCTACATAAAGGAGTAACT
>67.2|6251598|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TATTGAGGGCGGTGTTTATGCACTCAGGGAAAGGA
>67.3|6251670|38|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AACAGCATCAGGAATTTATGTTCACGTTGCGAACCAGG
>67.4|6251745|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CTGTTCATGGGATAACCTAATCAAGAGAGCATAGAC
>67.5|6251818|38|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TCTGCGGGCTGATTTCACCCCAATCCAAACTGAGGAAG
>67.6|6251893|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TCATCCTCGACAACGAAGAATAAAATCATTATCGA
>67.7|6251965|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CAACCTCCATCGCTATCTGGCGGGCAATCCGCAGG
>67.8|6252037|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AAGTTCGTTTCTTCTCTTTTGAAGTAACAATAGGC
>67.9|6252109|38|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CGTGCGGGCTTCCTTCTTCCCTGGGTTTCTTCGGTTGC
>67.10|6252184|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TGACCGCACGATCGCACTCTGCGATCGCCACGCACAA
>67.11|6252258|32|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CTCGACTGGGCCGCGCAGCTTTATGGGTTCAC
>67.12|6252327|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ATGGGAGGCTACATCAGAAGCGAGAATTGGTTTAAG
>67.13|6252400|39|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ATTCAAAACAAGCGTGGTGCTGCTCAAATGTGGGCGCAT
>67.14|6252476|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTTGCCTCCGTTAGGGCGATCGCCCCCATAATCATT
>67.15|6252549|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ATTTCGTTTTGGAGTTTGGCTGAGAGCATGGACAGGG
>67.16|6252623|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CCGAGGCAGTTTCGGATAGTGACCGTGAGGCGATCG
>67.17|6252696|38|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AATAGTATTGTGCCAATAATGGCAACAATTTCAACCGA
>67.18|6252771|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AAAATAGAAAAATAACGAAAAGCCCAATTTTCAATAT
>67.19|6252845|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AAACTAGATTTCCGTTTTGACATGGCGGAGTGCGG
>67.20|6252917|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GGACAGAAACTCAGTCGGACGATTGCGGACTTACGA
>67.21|6252990|37|NC_019693|CRISPRCasFinder,CRT
AGGATAGGCGATTCCCAAAAACAGAACGACGGGAAAA
>67.22|6253064|37|NC_019693|CRISPRCasFinder,CRT
CTGAACAAGACGATGAATCTTAAGAGCAGGAATTAGA
>67.23|6253138|37|NC_019693|CRISPRCasFinder,CRT
TACCAAAGGGGAGTGACATTCACCTATTGAGTATGAA
>67.24|6253212|34|NC_019693|CRISPRCasFinder,CRT
TTTAGTAGATGGAAAGGACTGATTGTAACGGCTG

CRISPR arrays and Neighbor proteins around NC_019693_67

CRISPR arrays

The CRISPR arrays of NC_019693_67

>merge|NC_019693|67|6251489-6253282|PILER-CR,CRISPRCasFinder,CRT
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAACATCGTTGAGGTGAAGGGCTACATAAAGGAGTAACTCTTTCATTACAATGAATCCCGGCAACGGGATTGAAACTATTGAGGGCGGTGTTTATGCACTCAGGGAAAGGACTTTCATTACAATGAATCCCGGCAACGGGATTGAAACAACAGCATCAGGAATTTATGTTCACGTTGCGAACCAGGCTTTCATTACAATGAATCCCGGCAACGGGATTGAAACCTGTTCATGGGATAACCTAATCAAGAGAGCATAGACCTTTCATTACAATGAATCCCGGCAACGGGATTGAAACTCTGCGGGCTGATTTCACCCCAATCCAAACTGAGGAAGCTTTCATTACAATGAATCCCGGCAACGGGATTGAAACTCATCCTCGACAACGAAGAATAAAATCATTATCGACTTTCATTACAATGAATCCCGGCAACGGGATTGAAACCAACCTCCATCGCTATCTGGCGGGCAATCCGCAGGCTTTCATTACAATGAATCCCGGCAACGGGATTGAAACAAGTTCGTTTCTTCTCTTTTGAAGTAACAATAGGCCTTTCATTACAATGAATCCCGGCAACGGGATTGAAACCGTGCGGGCTTCCTTCTTCCCTGGGTTTCTTCGGTTGCCTTTCATTACAATGAATCCCGGCAACGGGATTGAAACTGACCGCACGATCGCACTCTGCGATCGCCACGCACAACTTTCATTACAATGAATCCCGGCAACGGGATTGAAACCTCGACTGGGCCGCGCAGCTTTATGGGTTCACCTTTCATTACAATGAATCCCGGCAACGGGATTGAAACATGGGAGGCTACATCAGAAGCGAGAATTGGTTTAAGCTTTCATTACAATGAATCCCGGCAACGGGATTGAAACATTCAAAACAAGCGTGGTGCTGCTCAAATGTGGGCGCATCTTTCATTACAATGAATCCCGGCAACGGGATTGAAACTTTGCCTCCGTTAGGGCGATCGCCCCCATAATCATTCTTTCATTACAATGAATCCCGGCAACGGGATTGAAACATTTCGTTTTGGAGTTTGGCTGAGAGCATGGACAGGGCTTTCATTACAATGAATCCCGGCAACGGGATTGAAACCCGAGGCAGTTTCGGATAGTGACCGTGAGGCGATCGCTTTCATTACAATGAATCCCGGCAACGGGATTGAAACAATAGTATTGTGCCAATAATGGCAACAATTTCAACCGACTTTCATTACAATGAATCCCGGCAACGGGATTGAAACAAAATAGAAAAATAACGAAAAGCCCAATTTTCAATATCTTTCATTACAATGAATCCCGGCAACGGGATTGAAACAAACTAGATTTCCGTTTTGACATGGCGGAGTGCGGCTTTCATTACAATGAATCCCGGCAACGGGATTGAAACGGACAGAAACTCAGTCGGACGATTGCGGACTTACGACTTTCATTACAATGAATCCCGGCAACGGGATTGAAACAGGATAGGCGATTCCCAAAAACAGAACGACGGGAAAACTTTCATTACAATGAATCCCGGCAACGGGATTGAAACCTGAACAAGACGATGAATCTTAAGAGCAGGAATTAGACTTTCATTACAATGAATCCCGTTGCCGGGATTGAAACTACCAAAGGGGAGTGACATTCACCTATTGAGTATGAACTTTCATTACAATGAATCCCGGCAACGGGATTGAAACTTTAGTAGATGGAAAGGACTGATTGTAACGGCTGCTTTTATTACAATGAATCCCGGCAACGGGATTGAAAC

>NC_019693|67|8|6251489-6252989|PILER-CR
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	ATCGTTGAGGTGAAGGGCTACATAAAGGAGTAACT
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TATTGAGGGCGGTGTTTATGCACTCAGGGAAAGGA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AACAGCATCAGGAATTTATGTTCACGTTGCGAACCAGG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CTGTTCATGGGATAACCTAATCAAGAGAGCATAGAC
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TCTGCGGGCTGATTTCACCCCAATCCAAACTGAGGAAG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TCATCCTCGACAACGAAGAATAAAATCATTATCGA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CAACCTCCATCGCTATCTGGCGGGCAATCCGCAGG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AAGTTCGTTTCTTCTCTTTTGAAGTAACAATAGGC
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CGTGCGGGCTTCCTTCTTCCCTGGGTTTCTTCGGTTGC
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TGACCGCACGATCGCACTCTGCGATCGCCACGCACAA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CTCGACTGGGCCGCGCAGCTTTATGGGTTCAC
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	ATGGGAGGCTACATCAGAAGCGAGAATTGGTTTAAG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	ATTCAAAACAAGCGTGGTGCTGCTCAAATGTGGGCGCAT
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TTTGCCTCCGTTAGGGCGATCGCCCCCATAATCATT
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	ATTTCGTTTTGGAGTTTGGCTGAGAGCATGGACAGGG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CCGAGGCAGTTTCGGATAGTGACCGTGAGGCGATCG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AATAGTATTGTGCCAATAATGGCAACAATTTCAACCGA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AAAATAGAAAAATAACGAAAAGCCCAATTTTCAATAT
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AAACTAGATTTCCGTTTTGACATGGCGGAGTGCGG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	GGACAGAAACTCAGTCGGACGATTGCGGACTTACGA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC

>NC_019693|67|65|6251489-6253282|CRISPRCasFinder
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	ATCGTTGAGGTGAAGGGCTACATAAAGGAGTAACT
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TATTGAGGGCGGTGTTTATGCACTCAGGGAAAGGA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AACAGCATCAGGAATTTATGTTCACGTTGCGAACCAGG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CTGTTCATGGGATAACCTAATCAAGAGAGCATAGAC
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TCTGCGGGCTGATTTCACCCCAATCCAAACTGAGGAAG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TCATCCTCGACAACGAAGAATAAAATCATTATCGA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CAACCTCCATCGCTATCTGGCGGGCAATCCGCAGG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AAGTTCGTTTCTTCTCTTTTGAAGTAACAATAGGC
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CGTGCGGGCTTCCTTCTTCCCTGGGTTTCTTCGGTTGC
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TGACCGCACGATCGCACTCTGCGATCGCCACGCACAA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CTCGACTGGGCCGCGCAGCTTTATGGGTTCAC
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	ATGGGAGGCTACATCAGAAGCGAGAATTGGTTTAAG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	ATTCAAAACAAGCGTGGTGCTGCTCAAATGTGGGCGCAT
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TTTGCCTCCGTTAGGGCGATCGCCCCCATAATCATT
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	ATTTCGTTTTGGAGTTTGGCTGAGAGCATGGACAGGG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CCGAGGCAGTTTCGGATAGTGACCGTGAGGCGATCG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AATAGTATTGTGCCAATAATGGCAACAATTTCAACCGA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AAAATAGAAAAATAACGAAAAGCCCAATTTTCAATAT
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AAACTAGATTTCCGTTTTGACATGGCGGAGTGCGG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	GGACAGAAACTCAGTCGGACGATTGCGGACTTACGA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AGGATAGGCGATTCCCAAAAACAGAACGACGGGAAAA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CTGAACAAGACGATGAATCTTAAGAGCAGGAATTAGA
CTTTCATTACAATGAATCCCGTTGCCGGGATTGAAAC	TACCAAAGGGGAGTGACATTCACCTATTGAGTATGAA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TTTAGTAGATGGAAAGGACTGATTGTAACGGCTG
CTTTTATTACAATGAATCCCGGCAACGGGATTGAAAC

>NC_019693|67|7|6251489-6253282|CRT
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	ATCGTTGAGGTGAAGGGCTACATAAAGGAGTAACT
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TATTGAGGGCGGTGTTTATGCACTCAGGGAAAGGA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AACAGCATCAGGAATTTATGTTCACGTTGCGAACCAGG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CTGTTCATGGGATAACCTAATCAAGAGAGCATAGAC
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TCTGCGGGCTGATTTCACCCCAATCCAAACTGAGGAAG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TCATCCTCGACAACGAAGAATAAAATCATTATCGA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CAACCTCCATCGCTATCTGGCGGGCAATCCGCAGG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AAGTTCGTTTCTTCTCTTTTGAAGTAACAATAGGC
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CGTGCGGGCTTCCTTCTTCCCTGGGTTTCTTCGGTTGC
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TGACCGCACGATCGCACTCTGCGATCGCCACGCACAA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CTCGACTGGGCCGCGCAGCTTTATGGGTTCAC
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	ATGGGAGGCTACATCAGAAGCGAGAATTGGTTTAAG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	ATTCAAAACAAGCGTGGTGCTGCTCAAATGTGGGCGCAT
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TTTGCCTCCGTTAGGGCGATCGCCCCCATAATCATT
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	ATTTCGTTTTGGAGTTTGGCTGAGAGCATGGACAGGG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CCGAGGCAGTTTCGGATAGTGACCGTGAGGCGATCG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AATAGTATTGTGCCAATAATGGCAACAATTTCAACCGA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AAAATAGAAAAATAACGAAAAGCCCAATTTTCAATAT
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AAACTAGATTTCCGTTTTGACATGGCGGAGTGCGG
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	GGACAGAAACTCAGTCGGACGATTGCGGACTTACGA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	AGGATAGGCGATTCCCAAAAACAGAACGACGGGAAAA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	CTGAACAAGACGATGAATCTTAAGAGCAGGAATTAGA
CTTTCATTACAATGAATCCCGTTGCCGGGATTGAAAC	TACCAAAGGGGAGTGACATTCACCTATTGAGTATGAA
CTTTCATTACAATGAATCCCGGCAACGGGATTGAAAC	TTTAGTAGATGGAAAGGACTGATTGTAACGGCTG
CTTTTATTACAATGAATCCCGGCAACGGGATTGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015151029.1|6250266_6251220_+|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl|CDD|379100
NC_019693.1|WP_015151036.1|6259611_6261228_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
NC_019693.1|WP_015151032.1|6256111_6256894_+|nickel-pincer-cofactor-biosynthesis-protein-LarB	unknown	unknown	gnl|CDD|224605
NC_019693.1|WP_156823958.1|6256943_6257420_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151034.1|6257511_6258177_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NC_019693.1|WP_015151026.1|6242198_6245162_-|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	cas10d	cd09712_cas10d_CAS-I-D	gnl|CDD|187843
NC_019693.1|WP_015151023.1|6239369_6240182_-|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl|CDD|337605
NC_019693.1|WP_015151019.1|6233750_6234689_+|ParA-family-protein	unknown	unknown	gnl|CDD|224113
NC_019693.1|WP_015151024.1|6240171_6240942_-|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	gnl|CDD|274458
NC_019693.1|WP_015151022.1|6238807_6239155_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NC_019693.1|WP_015151035.1|6258286_6259495_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NC_019693.1|WP_015151025.1|6241104_6242091_-|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	gnl|CDD|375747
NC_019693.1|WP_015151028.1|6249510_6249789_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044195918.1|6263520_6265365_-|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|119407
NC_019693.1|WP_015151038.1|6262278_6262971_-|deoxyribose-phosphate-aldolase	unknown	unknown	gnl|CDD|234784
NC_019693.1|WP_015147653.1|6247617_6249195_-|IS1182-family-transposase	unknown	unknown	gnl|CDD|372705
NC_019693.1|WP_015151031.1|6254115_6255876_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173865
NC_019693.1|WP_015151030.1|6253570_6254053_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl|CDD|376811
NC_019693.1|WP_015151027.1|6245455_6247525_-|type-I-D-CRISPR-associated-helicase-Cas3'	cas3	cd09710_cas3_CAS-I-D	gnl|CDD|187841
NC_019693.1|WP_015151037.1|6261306_6262230_-|DNA-repair-protein-RecO	unknown	unknown	gnl|CDD|234622

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_015151029.1|6250266_6251220_+|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	4.6e-21	70.3	4.7
NC_019693.1|WP_015151023.1|6239369_6240182_-|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	1.2e-22	75.5	0.0
NC_019693.1|WP_015151025.1|6241104_6242091_-|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	6.3e-75	246.8	0.0
NC_019693.1|WP_015151026.1|6242198_6245162_-|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	cas10d	cd09712_cas10d_CAS-I-D	2.6e-205	678.8	0.0
NC_019693.1|WP_015151027.1|6245455_6247525_-|type-I-D-CRISPR-associated-helicase-Cas3'	cas3	cd09710_cas3_CAS-I-D	4e-59	195.1	0.0
NC_019693.1|WP_015151024.1|6240171_6240942_-|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	7.6e-54	177.1	0.2
NC_019693.1|WP_015151022.1|6238807_6239155_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1.5e-20	68.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015151029.1|6250266_6251220_+|WYL-domain-containing-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	1.1678e-21
NC_019693.1|WP_015151036.1|6259611_6261228_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.16762e-69
NC_019693.1|WP_015151032.1|6256111_6256894_+|nickel-pincer-cofactor-biosynthesis-protein-LarB	gnl|CDD|224605	COG1691, COG1691, NCAIR mutase (PurE)-related proteins [General function prediction only].	3.08517e-113
NC_019693.1|WP_015151034.1|6257511_6258177_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	3.44246e-26
NC_019693.1|WP_015151026.1|6242198_6245162_-|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	gnl|CDD|187843	cd09712, Cas10d_I-D, CRISPR/Cas system-associated protein Cas10d. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain. Fused to N-terminal HD domain; signature gene for I-D subtype; also known as Csc3 family.	0
NC_019693.1|WP_015151023.1|6239369_6240182_-|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|337605	pfam10040, CRISPR_Cas6, CRISPR-associated endoribonuclease Cas6. Cas6 is a member of the RAMP (repeat-associated mysterious protein) superfamily. It is among the most widely distributed Cas proteins and is found in both bacteria and archaea. Cas6 functions in the generation of CRISPR-derived guide RNAs for invader defense in prokaryotes.	2.16129e-13
NC_019693.1|WP_015151019.1|6233750_6234689_+|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	5.68206e-52
NC_019693.1|WP_015151024.1|6240171_6240942_-|type-I-D-CRISPR-associated-protein-Cas5/Csc1	gnl|CDD|274458	TIGR03159, cas_Csc1, CRISPR type I-D/CYANO-associated protein Csc1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family is a CRISPR-associated (Cas) family strictly associated with the Cyano subtype of CRISPR/Cas locus, found in several species of Cyanobacteria and several archaeal species. This family is designated Csc1 for CRISPR/Cas Subtype Cyano protein 1, as it is often the first gene upstream of the core cas genes, cas3-cas4-cas1-cas2.	1.17237e-55
NC_019693.1|WP_015151022.1|6238807_6239155_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.13602e-21
NC_019693.1|WP_015151035.1|6258286_6259495_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	7.04906e-67
NC_019693.1|WP_015151025.1|6241104_6242091_-|type-I-D-CRISPR-associated-protein-Cas7/Csc2	gnl|CDD|375747	pfam18320, Csc2, Csc2 Crispr. The Csc2 Crispr family of proteins forms a core RNA recognition motif-like domain, flanked by three peripheral insertion domains: a lid domain, a Zinc-binding domain and a helical domain. The CRISPR-Cas system is possibly a mechanism of defence against invading pathogens and plasmids that functions analogously to the RNA interference (RNAi) systems in eukaryotes.	0
NC_019693.1|WP_044195918.1|6263520_6265365_-|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	6.06401e-76
NC_019693.1|WP_015151038.1|6262278_6262971_-|deoxyribose-phosphate-aldolase	gnl|CDD|234784	PRK00507, PRK00507, deoxyribose-phosphate aldolase; Provisional.	1.02868e-112
NC_019693.1|WP_015147653.1|6247617_6249195_-|IS1182-family-transposase	gnl|CDD|372705	pfam13751, DDE_Tnp_1_6, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	8.15327e-14
NC_019693.1|WP_015151031.1|6254115_6255876_+|ABC-transporter-substrate-binding-protein	gnl|CDD|173865	cd08500, PBP2_NikA_DppA_OppA_like_4, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NC_019693.1|WP_015151030.1|6253570_6254053_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl|CDD|376811	pfam02542, YgbB, YgbB family. The ygbB protein is a putative enzyme of deoxy-xylulose pathway (terpenoid biosynthesis).	4.72048e-98
NC_019693.1|WP_015151027.1|6245455_6247525_-|type-I-D-CRISPR-associated-helicase-Cas3'	gnl|CDD|187841	cd09710, Cas3_I-D, CRISPR/Cas system-associated protein Cas3; Distinct diverged subfamily of Cas3 helicase domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Diverged DNA helicase Cas3'; signature gene for Type I and subtype I-D.	5.03643e-55
NC_019693.1|WP_015151037.1|6261306_6262230_-|DNA-repair-protein-RecO	gnl|CDD|234622	PRK00085, recO, DNA repair protein RecO; Reviewed.	1.36861e-57

Protein sequences

>NC_019693.1|WP_015151029.1|6250266_6251220_+|WYL-domain-containing-protein
MPVRYSHIALALHILELLAERDRDRNEILDLVGEFLYENNSSIEDVKQKFDRTLRELRDWGFKIDHRPYSLVESNFPIILSASQRHTLYRAAHFLTEMNFATEAQQLVRLSQLGESDSPPDIQVDFAPPTNYSAPQCRRLLEQLQDRCAQKYRFTLRYIDSQKQELTMDLDRCELRLHDGTLYLFAFVPDLEQYHRNLRPELVYRNWLFRVDRIKSVGPPSTQAWVYSSFPTLTIRYRMTGPLANYVPRRIHEQVIERNLKQKYVEIETQEDYPFWFRQRILRYGSNARVIDPPWIVEEIATILRKAASNYDDIPGP
>NC_019693.1|WP_015151028.1|6249510_6249789_-|hypothetical-protein
MIKINHSRQSKNSQAPQTLPLLKPGSLGWVNPQINENLLKSDSLTTKQVEERFGIPATNLRCCHINYVLPWKTYLIFHQGRDRWKIYTEAAV
>NC_019693.1|WP_015147653.1|6247617_6249195_-|IS1182-family-transposase
MRPPLWHPPVELSDSEQVIINRIKKAKLFTFLRLNRLFIFDDEFQEELNTIFKDSTMGNCPVAPAQLALATILQAYMGISDEEVIEELVMDLRWQLALNCLNCEKPPFSKATLIRFRSALIKKGFDQRLIDRTVDIAKLKGGFGSANLRAALDSSPLWGAGKVEDTYNLLGHALRKALSIIASQQGWGLAEIANEAGADFVNSSSLKAALDLNWDDPAESQKALSTILKSLNSVEEWIQQQSNPDEIEEAQAPLQVARLIESQNVTLDTMGVPKLAKGVAKDRRISIEDPDMRHGRKSRSQKINGYKRHILKDLDIGVIRAVAVTRANTPEAAATVDLEVDLKRQQVQLNELHIDRAYLSSHWVKERSEQLQIFCKAWPVRNSGRFDKNAFVFDWDNQVISCPNQVIMPFEPGKIVHFPKPECAACPLRERCTTSKNGRSISIHPDEGLMQELRQRQSTSSGRAQLRERTSVEHSLAHVGQWQDKRARYIGQRKNLFDLRRVAVVHNLHVIARMNEVLPIQQAAL
>NC_019693.1|WP_015151027.1|6245455_6247525_-|type-I-D-CRISPR-associated-helicase-Cas3'
MKLNLKPLYSQLNPGVGHCPLKCQDRCLVQERAPTLKPPPGYTCPLSSHQAETYQAVVEGDADIIFNKSATGDGKTLSGALPSLLDEGFRLMALYPTIELVEDQTQQQRGYHQLFGLDADSRIDRLFGEELNRRVQDESSNKFQELLRAIYHKPILLTNPDIFHFITHYRYRQSAFDPSLLPLALAEWPDLWMFDEFHIFGPHQEAAALNSLTLIRRTQQDKRPRRFLFTSATPKRDFIAQLQQAEFKVREISGRYTSEETPGYRQILQAISLEFVELGEGDAVQWLVESADQLRIALPPGGRGLIILNSIAAVNRVVRKLADALPGVRVREISGRIDRRLRSQIQGELKDSQDPVLIVATSAVDVGVDFRIHLLICEGSDAATVVQRLGRLGRHPGFAEYRAFVLVSRRTPWVIPRLQQAIAGEDTLDRTQFHEAIAEAFEPPKAFEEYRQHWGALQAQGMMVTMSQENAQVSQSIRDRMTEDLNRVYPNRLESARRQWFAMMGNPVGKATQEELLRFRGGTALQAAVWDDGRFYTYDLLRLLPYAKVELCDRETFLTAATAAGYGTESFPEAYIQVYLRVQEWVEKRISLTLSTSRDTDELHAGELCLLDRLMTVGHPQEQVKRCLQRRKFLAFLVPVNRTQPSSHWQVADKLQLPPTFGLYRLTDAGGRTYACAFNQDALLLEASK
>NC_019693.1|WP_015151026.1|6242198_6245162_-|type-I-D-CRISPR-associated-protein-Cas10d/Csc3
MASLLQNVIKITLDPDTDPILAQYIDLVLPAVEREFSSISALGGDYETHYQQLKQRGDNHAVEKAQRWSDRPDQNLCVHVLNALLIAWNLAENYLNSPLSDEEKRLLCLGITLHDYNKYCHGQGEEAPKAYEVPEILSLCQEMGRRLNFQAFWPEWESYLSDIGFLAQNTQFKVGTNPYPSNWPKFAIAHSGRLTCPLRHLLAFADIAVHLKDAADIKKDPENINPEKGGKRLREHLRDLNIKKTLVYHHLRDTIGILTNRIHDATLNFAAEQDWQPLIFFARGVVYLAPLKPEPPNREELQEFVWQQISQVLSQKMLEGDIGFKRDGKGLKVAPQTSELFTPEDLIRQLPPVIEVRVNNPNNLATPKRLDKLVTEKKLTPEEREYLSRGEDLRSDRLAEFLIVVQREFLADCPDYVDWILEALKLKDCLTLEQIQITIGGVNYGWYRAAAHYFCQHGTLDGEQTLELLTDLANRLATWATENQLLPQYRSPTREIFNQYLERYLDIAGWETIVPPFEAELATYSFAKTRKGKQPICSLSSGEFASEDQMDSVVLFKPQQYSNKNALGGGQIKRGISKIWSLEMLLRQALWSVRSGKLEEQQPVFLYIFPAYVYAPQIIRAIRGLMVELQSVSLWKIREHWLKCGMDVSRLSELDWLSEDRDIGEKARQVYDTKDLPFMATTHTTTLGKTVTDAWVYLAFLALVLPKLLGVRVVATSSNVPLYSSDREFVGSAVLDGAAGFWSLLQCPPSVRTEQLDRILMRLLIVYSLHLDNRSNPPDARWGALNGTVRDVMTDILNIFAIAQEGLRSHKRDYPSSEEVARYWQFAQIWSQLDKTMVEKLNLITQLVQQYRTFYQVNITDSSHAILLPISKALETILSVPTQVDQEDLILQGAGLLKDAIDRQPAYTRPLLMDKSLDIAIRQQRELEAIYQFMETCVRDLFGTLYRGDRALLQENRNRIKSGAEFAYRWLALQEKNQKNLDSKTRS
>NC_019693.1|WP_015151025.1|6241104_6242091_-|type-I-D-CRISPR-associated-protein-Cas7/Csc2
MSQLEKIQSSFSKQFPRLAGGRYVQFLMLRHSQSFPVFQTDGVLNTARTQAGIESPEMMSRLVMFKRKQTTPERLTGRELLRSLGITSGEIDAPNYCEYNGEKSCKKCPDCILYGFAIGDSGSERSKVYSDSAFSLTAYEQSHRSFTFNAPFEGGTMSEGGKMRSAINELDHVIPEVTFPTVETLRDSTYEGFLYVLGNLIRTRRYGAQESRTGTVKNHLLGIVISDGEIFSNLHFTQALYDALKGDTTAAIADIKAQATTVIHTLLAEEPVRIYQTITGEPLKTLLDEVLAIYQNEAALTPIISTLATQTQTYSETYGAESNKKKKR
>NC_019693.1|WP_015151024.1|6240171_6240942_-|type-I-D-CRISPR-associated-protein-Cas5/Csc1
MVLYYCRLKLHDNVFFATREMGILYETEKYLHNWALTYAIFSGSYLPHPYHSQPAQQPGYLDPKNEQNLFFLNPEKIYVFPALPLRCFYQVNTFKAAQTTYYGKSKQFGEKGANRNYPINYGRAKELAVGSEYATYLFAPEPLYIPQWIRLGKWMAKVHLTKYPIPKTAMQAKTGEYACPHPLNPLDLPSQQQIMLYNRIVMPPVSLITESQLVGEYWELSGDDWDSFRANLPELPKKVCLPRGIIYGAGVTADVR
>NC_019693.1|WP_015151023.1|6239369_6240182_-|CRISPR-associated-endoribonuclease-Cas6
MSDNLDGLYSLVVELRAIESGNPPATLGRALHALVLNWLNLANPELATATHDLAVSPFSVSGLIGNRRPNEVKGGDCFHLKIGVLDSQLIQPLLTGLTQWAMQPIILAKFPFLMTRTYMIHESHPLANVSSYSKLVEAAGNQSLIELTFLSPTSFKQKQGIQTFPLPELVFGNLQRRWNNFAPEPLHFPEIEWQGLVSAYELKTHALKLEGGAEIGAQGWIRYRFSDPEQAKIARILAEFAFYAGVGRKTTMGMGQTQFNSSTKPKPIKR
>NC_019693.1|WP_015151022.1|6238807_6239155_-|CRISPR-associated-endonuclease-Cas2
MGVTRQSHVTRVHAFLYLVVYDLPATKAGNKRRQRLHDLLFGYGNWKQYSLFECFLSTKQFVTLQHKIEDLIKPAEELLCIYILDSTGIQRTIVYGTQQFSLWQKTVQVPLRPVW
>NC_019693.1|WP_015151019.1|6233750_6234689_+|ParA-family-protein
MAYIISTINMKGGVGKTTLTVNLAACLAKDYQKRVLVVDLDTQISATLSLVSPHDFSKLRKEKRTLKHLVNDFIQPIDQKSLPIQDIIKPYIGNVKGLDLLPGDLEIYDDFMVSEVLHRKALRLGKDNFEEVWTKLEQILVRGILDPVMKDYDFIILDCAPGYNLLTRSALVASDYYLLPAKPEPLSLIGIQLLERRINQLREVYKNENPLDLDMVGIVFSMSGNVLTGRYYRQVMRRVHDDFGETKIFKTRIPMDVNVSKAVDSFLPVFLTHPTSIGAKAFSQLTDEFMQKLQIIVEMKEQRNKLNLVNLD
>NC_019693.1|WP_015151030.1|6253570_6254053_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MNIRIGNGYDIHQLVSDRPLILGGIRIPHELGLLGHSDADVLTHAIMDAMLGALSLGDIGLYFPPSDPQWAGADSLKLLAQVHQLILERGWEVGNIDSVVVAERPKLKPHISAMRDRLAQVLNIEGDRIGIKATTNEKLGPVGREEGIAAYAVTLLVTQP
>NC_019693.1|WP_015151031.1|6254115_6255876_+|ABC-transporter-substrate-binding-protein
MMVKKYWQQGVAIALTVFMGISLSSCNPAQFKTSAAQTPLVLSILSDPKTFNYALSEESPNIFGYTYEGLVSENPLTGEVEPILAESWEISQNGLQIIFTLRENLRWSDGQPLTVDDVVFTYNDIYFNDKIPSSTADVLRIGESRTFPTVRKLDDRRVEFTVVEPFAPFLRAAGLPILPAHALQESVETLDREGNPVFLSTWGINTPPQEIIVNGPYKLASYRPSERVFFEKNPYYWRNPQPYIERISWEVVESQDTGVVQFLSGILDSISVRPEDFSLLKKQEERNNFKILYELEPAPGITFMTFNLNKGRFEDSNRPVVDPIKSRWFNSLKFRQAIAYATDRETMIENTFQGLGRPINSHISVQSPYYLTPEEGLKVYDFDAEKARQLLQEDGFTYNNQGQLLDSEGNRVRFTLITNAGNKIREAMGAQIKQNLSQIGIQVDFQPLAWNAVITKLSDSLDWEALIIGFGGGTEPHWSSNLWLPEGRLHMFNQPRQVGQTPLVGREIADWERRLGDLYIQASQEIDEAKRKELYVETQRITQEYLPVIQLVNQLSMTALRNRVQGVEYSSLGGAFWNIHELQLEE
>NC_019693.1|WP_015151032.1|6256111_6256894_+|nickel-pincer-cofactor-biosynthesis-protein-LarB
MNPETLQSLLEAVAAGKVSPSTAVEELKYLGFEPVGDFARIDRHRALRTGFPETIWGPGKTPEQIADIILSMREHNPVVMATRITPEVFAEIEERVHGLYYYPTARICSTAIAPAIPNYPGKIGILCAGTADLPVAEEAAIVAELSGFEVKRYWDVGVAGIHRLLASWRAIAEADVLIVVAGMEGALPSVVAGLANAPTIAVPTSIGYGASFNGLAPLLTMLNSCAAGVGVVNIDNGYGAAILAGQILRTAQRIPEKDSP
>NC_019693.1|WP_156823958.1|6256943_6257420_-|hypothetical-protein
MIQRFKMRSLIGFSLVLLLPLASCVGTGLEETQAVTNGMSMEKRSEIFILPGVVIKKPWTKNTESWNAGGGDYYVLDVGDARVRERSAEEGVILRPSDAVSMAQFEEFVGSSVEVSGEYIAAQPYVPESPMESYPTDMEGNPLPRGSGFKVYQITPVP
>NC_019693.1|WP_015151034.1|6257511_6258177_-|Uma2-family-endonuclease
MNPATLSSSRLNPNLPKWQPATWEDYLAYCDAENFEAGRAFYHQGYLWIDMGNEGIDHARVNNLFAMLFFLWFSQRGQIWDDLGGCVLEKPQQQGAAPDRLVYIGAGSPQWQAGERRRINLDIWRVPDLVGEVSDTTLATDLDEKKQLYAALKIPEYWAIDIQGKRVIAFCLQENGKYEQVNFSVALEGLPIALLSQTLERLTHETNGTAAQWFAQQIANL
>NC_019693.1|WP_015151035.1|6258286_6259495_-|glycosyltransferase-family-4-protein
MHIAWLGKKTPFCGNVTYSREVTNALLDRGHQVSFFHFAQQEAVEEAENLPQLESELALKTGNGWPVAACEVSLPCLYKSTIYTIPTPKSRKVLTQALRDLRPDLVHASLTLSPLDFVLPEICEELNLPLVATFHPPFAHHRSLRSGRQHLQHLTYQLYAPFLPNYDKTIVFSQLQRELLGKLGVPSQQVAVIPNGVDVQKYSPGYSQIKYELNADRLFVYQGRIAMEKNVEALLKAWKQADLGPSCKLAIVGDGPLAPSLEGYAGAEHNVIWLGYVADEQRRIEILRGADVFILPSLVEGLSLSLLEAMACGLACIATDVGADGEVLAEGAGVVLSAQGVTTQLKTLLPLLKEQPEFTSLLGRKARQRVLDRYTLSRNISQLELMYEEILQERPMPVTQWA
>NC_019693.1|WP_015151036.1|6259611_6261228_-|MFS-transporter
MPLSDSNLETQVPHWNPSNSSQKHQNQRGGGHHQTQYRRPVQAEKLEEIDRNNRQPGHSNGRSPTSPAQPRPAVTSPPPESEHTLSKNGSGPMEENVQPPAPPEPERGFMPVLKNRNFLVLWSGQVFSQLADKVYLVLMIGLVASRFQAEGQSISGWVSAIMVAFTIPAVLLGSLAGALTDRWSKKGILVSTNLVRGIFVLSLPLLLFLSEGFHLGTLPLGFALMLMVTFFVSTLTQFFAPAEQAVIPLILERRLLLPANSLYTTTMMASVIVGFAVGEPLLAIADRTFGHIGDGVGIGKELVVGGSYCIAGLLLLMMKTGEKSNPPDTEYPHVFEDIRDGWQYLSNHQRIKSALIQLVILFSIFAALAVLAVRLAEVIPNLRTDQFGFLLAAAGAGMGAGAALLGHFGQHISHRRLSLFGSIGMALSLGSLSLFGAQLWAALGLITVLGVFASFVGVPMQTTIQAETPEEMRGKVFGLQNNAINIALTLPLALAGVAESMFGLTVVLLSLGAIAIAGGVVSWYISETEPHPSTPRPE
>NC_019693.1|WP_015151037.1|6261306_6262230_-|DNA-repair-protein-RecO
MSRTYKATGINLKSIPLGESDRILTILTRECGLIRAVAPGVRLPKSKLGGRAGLFVVNELVITQGRSLDRITQAETLESYPGLSKDLGKLTAGQYLAELALCQALSDQPQEELFSLLSEHLSRIEGVSIVGDRPSTTQVLPLLTQGIYHLLALGGIAPQVHACCLTQCPLTPDFQSLNWRVGFSTSAGGIVSLANENRPANSGAVPKSGPSNRSSPSVQAATLPRKVDRQLNAVELAILQQLTGAELPQETHLNLQIQGMMGERPSVDQVWVSIEHLLRHYAQYHYGQSIRSATLMDTYIHSSRASF
>NC_019693.1|WP_015151038.1|6262278_6262971_-|deoxyribose-phosphate-aldolase
MAANQGDIDIAPLIDHSLLNPAATPKQVEQWCEEADRFKFASVCVYPAYVRQATNYLHGKSPKVCTVIGFPTGGSTSATKLYEAQEAADNGATELDVVINIGWLKAGKNNDVHDEIAAICDKTDRPVKAILETNLLTDQEKRVAAEICMDAGVAYLKTCTGFAGGATVADVELLKKIGRGQVGVKASGGIRTVDQAIDLIIAGATRLGTSWGPHFLGLTSPGDAESNEDQ
>NC_019693.1|WP_044195918.1|6263520_6265365_-|N-acetylmuramoyl-L-alanine-amidase
MKVTPSINFPYRQNTPLKTAKLQNWILPSLISAFLLAAPPVEAAQLETWRFEADRNQLSFTTRGGVQPTAQLLSNPTRLVIDLPGTTLGRQNVTQPVGGAIREIRVGQFNPQTSRIVVELAAGYTLDPQQVEVKGSSPNQWSVQLPDPHTVGSPVAQGSSSPRSNSPSPLAATGGNTFLQEVEIKDEGFIFHTNGGTPTVELNQGSNGTWVNVDLPGVTLSPDLERRIRNVDRLGVNQLQLVQASSSPPLTRAILTLTEPDKNWQAQVSDRGEVLVWPEGEKPPEVTAQATSGLATIHGIELVGNQVVVKADRTLNYNTEWDQKTLAYRLTLYSSHLGNGVNRLQPERGSSVLWVRPTQEDPETVVVLVQPAAGVRVSGVEQQSGDRLAVQLESTEIVTTDPNAQLIPVVIPDSPPSVSPENQLQSEIPPTPAGRIAVVIDAGHGGSDPGAVGIGGLQEKDVVIDISHQVAEILEREGITAIMTRQDDRTIELAPRVQLANRVNANLFVSIHANAVNGARPEVNGLETYYYASGRNLAQAIQNSMLQDFSSMPNRGVKQARFYVLRHTSMPAVLVEVGFVTGRDDAPMLSDAAQRTRMAEAIARGILNYVRTNR

Crispr_ID: NC_019693_68

• CRISPR_ID: NC_019693_68
• CRISPR_location: 6286954-6287049
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_68

Consensus_repeat	Method
AAAACCCGCAGGCTGTAGCCCGGAGGC	CRISPRCasFinder

spacers of NC_019693_68

>68.1|6286981|42|NC_019693|CRISPRCasFinder
ATACGGACGAAGCCTGCCTGCGCGGGCTGTTATCATCAAATA

CRISPR arrays and Neighbor proteins around NC_019693_68

CRISPR arrays

The CRISPR arrays of NC_019693_68

>merge|NC_019693|68|6286954-6287049|CRISPRCasFinder
AAAACCCGCAGGCTGTAGCCCGGAGGCATACGGACGAAGCCTGCCTGCGCGGGCTGTTATCATCAAATAAAAACCCGCAGGCTGTAGCCTGGAGGC

>NC_019693|68|66|6286954-6287049|CRISPRCasFinder
AAAACCCGCAGGCTGTAGCCCGGAGGC	ATACGGACGAAGCCTGCCTGCGCGGGCTGTTATCATCAAATA
AAAACCCGCAGGCTGTAGCCTGGAGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015151049.1|6275328_6276276_-|hypothetical-protein	unknown	unknown	gnl|CDD|368438
NC_019693.1|WP_015151047.1|6272444_6273803_-|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	unknown	unknown	gnl|CDD|184646
NC_019693.1|WP_015151059.1|6288844_6289717_-|sugar-kinase	unknown	unknown	gnl|CDD|238912
NC_019693.1|WP_156823959.1|6273927_6275019_-|response-regulator	unknown	unknown	gnl|CDD|225971
NC_019693.1|WP_015151051.1|6278444_6279449_-|N-acetylglucosamine-kinase	unknown	unknown	gnl|CDD|225518
NC_019693.1|WP_015151063.1|6294759_6295410_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_019693.1|WP_015151061.1|6291715_6292864_+|histidinol-phosphate-transaminase	unknown	unknown	gnl|CDD|235053
NC_019693.1|WP_015151056.1|6286132_6286882_-|DUF561-domain-containing-protein	unknown	unknown	gnl|CDD|113257
NC_019693.1|WP_083896819.1|6288146_6288785_+|CDP-alcohol-phosphatidyltransferase-family-protein	unknown	unknown	gnl|CDD|223632
NC_019693.1|WP_015151065.1|6298304_6298559_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044197855.1|6293581_6294043_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151052.1|6279649_6282244_+|M1-family-metallopeptidase	unknown	unknown	gnl|CDD|223385
NC_019693.1|WP_015151066.1|6298686_6302259_+|response-regulator	unknown	unknown	gnl|CDD|223715
NC_019693.1|WP_015151055.1|6283410_6285900_-|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|225118
NC_019693.1|WP_015151060.1|6289836_6290940_-|inositol-3-phosphate-synthase	unknown	unknown	gnl|CDD|224180
NC_019693.1|WP_015151064.1|6295582_6298078_+|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|236901
NC_019693.1|WP_015151050.1|6276263_6278285_-|N-6-DNA-methylase	unknown	unknown	gnl|CDD|280533
NC_019693.1|WP_015151053.1|6282377_6282731_-|hypothetical-protein	unknown	unknown	gnl|CDD|227726
NC_019693.1|WP_015151054.1|6282811_6283393_-|hypothetical-protein	unknown	unknown	gnl|CDD|227672
NC_019693.1|WP_015151057.1|6287118_6287949_-|sulfurtransferase	unknown	unknown	gnl|CDD|225450

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015151049.1|6275328_6276276_-|hypothetical-protein	gnl|CDD|368438	pfam05430, Methyltransf_30, S-adenosyl-L-methionine-dependent methyltransferase. This family is a S-adenosyl-L-methionine (SAM)-dependent methyltransferase. It is often found in association with pfam01266, where it is responsible for catalyzing the transfer of a methyl group from S-adenosyl-L-methionine to 5-aminomethyl-2-thiouridine to form 5-methylaminomethyl-2-thiouridine.	1.29611e-31
NC_019693.1|WP_015151047.1|6272444_6273803_-|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	gnl|CDD|184646	PRK14360, glmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU.	0
NC_019693.1|WP_015151059.1|6288844_6289717_-|sugar-kinase	gnl|CDD|238912	cd01937, ribokinase_group_D, Ribokinase-like subgroup D. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.	8.50389e-47
NC_019693.1|WP_156823959.1|6273927_6275019_-|response-regulator	gnl|CDD|225971	COG3437, COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain [Transcription / Signal transduction mechanisms].	6.39002e-127
NC_019693.1|WP_015151051.1|6278444_6279449_-|N-acetylglucosamine-kinase	gnl|CDD|225518	COG2971, COG2971, Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism].	2.45326e-71
NC_019693.1|WP_015151063.1|6294759_6295410_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.58677e-10
NC_019693.1|WP_015151061.1|6291715_6292864_+|histidinol-phosphate-transaminase	gnl|CDD|235053	PRK02610, PRK02610, histidinol-phosphate transaminase.	0
NC_019693.1|WP_015151056.1|6286132_6286882_-|DUF561-domain-containing-protein	gnl|CDD|113257	pfam04481, DUF561, Protein of unknown function (DUF561). Protein of unknown function found in a cyanobacterium, and the chloroplasts of algae.	9.14964e-97
NC_019693.1|WP_083896819.1|6288146_6288785_+|CDP-alcohol-phosphatidyltransferase-family-protein	gnl|CDD|223632	COG0558, PgsA, Phosphatidylglycerophosphate synthase [Lipid metabolism].	2.49531e-19
NC_019693.1|WP_015151052.1|6279649_6282244_+|M1-family-metallopeptidase	gnl|CDD|223385	COG0308, PepN, Aminopeptidase N [Amino acid transport and metabolism].	1.4822e-177
NC_019693.1|WP_015151066.1|6298686_6302259_+|response-regulator	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.19527e-55
NC_019693.1|WP_015151055.1|6283410_6285900_-|SpoIIE-family-protein-phosphatase	gnl|CDD|225118	COG2208, RsbU, Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription].	3.56717e-57
NC_019693.1|WP_015151060.1|6289836_6290940_-|inositol-3-phosphate-synthase	gnl|CDD|224180	COG1260, INO1, Myo-inositol-1-phosphate synthase [Lipid metabolism].	0
NC_019693.1|WP_015151064.1|6295582_6298078_+|GAF-domain-containing-protein	gnl|CDD|236901	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS.	8.64421e-37
NC_019693.1|WP_015151050.1|6276263_6278285_-|N-6-DNA-methylase	gnl|CDD|280533	pfam02384, N6_Mtase, N-6 DNA Methylase. Restriction-modification (R-M) systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The R-M system is a complex containing three polypeptides: M (this family), S (pfam01420), and R. This family consists of N-6 adenine-specific DNA methylase EC:2.1.1.72 from Type I and Type IC restriction systems. These methylases have the same sequence specificity as their corresponding restriction enzymes.	1.01883e-27
NC_019693.1|WP_015151053.1|6282377_6282731_-|hypothetical-protein	gnl|CDD|227726	COG5439, COG5439, Uncharacterized conserved protein [Function unknown].	1.80249e-30
NC_019693.1|WP_015151054.1|6282811_6283393_-|hypothetical-protein	gnl|CDD|227672	COG5381, COG5381, Uncharacterized protein conserved in bacteria [Function unknown].	8.96724e-27
NC_019693.1|WP_015151057.1|6287118_6287949_-|sulfurtransferase	gnl|CDD|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	1.63116e-94

Protein sequences

>NC_019693.1|WP_015151056.1|6286132_6286882_-|DUF561-domain-containing-protein
MTMIPALDRAFQQGRALKIITGLTNFDADKVATVVRAADRGGATFLDIAADPALVKLAKQLTHLPICVSAVEPEKFLPCVEAGADLIEIGNFDAFYARGRRFEAAEVLQLTRETRALLPNIVLSITVPHILELDQQVDLAEELVKAGADIIQTEGGTSSNPVHPGILGAIEKAAPTLAAASAISRAVSVPVLCASGISTITAPMAIAAGAAGVGVGSAINRLDNELAAIAGVKSLVEALSTVSRSTIHA
>NC_019693.1|WP_015151055.1|6283410_6285900_-|SpoIIE-family-protein-phosphatase
MLTQSSPAPTPMPPPMNPIPLSRPRFQSLGKFRLRTVLVVPFIIPVLLSTGLVGWLSFRSGQQTVNELASQLRGEIALRVQEEMQRYLDRPHLVHHLNAQVFRQNGIDREDPEVLLEYFWEQSREFLDLGTIAYANERGEFVGVNPLEHYLVLSHEQTGRSLQRYAPREDGKLGELLRERPDYDARTRAWYQQAVTEGKPIWTRIEPSAIGQRLDISAVYPVYDRDRRFLGVLLWDIPLSGINQFLETLKIGKTGEAFILERNGLLVATSTQKATLIPGRNGEEPQRLPATESQNPRLSAALNALIAEFGSLENIKQSQGVEFFLEGARHFLQVMPFQDDRGIDWLILVGIPEADFMEEIHENTQQTVVLCFLALMVSISCGVAIAQWILRPILRVTRSSEQIANGQLDRHVYARGIIELEKLADAFNQMVDQLKASFNALEQANRDLIHHEQELAASKEQLEAVLNAVPGSISWINSSGTYLGVNRYLADSLNLDPEEMVGKKIGFAQNSHEYAEFMQQFLNGSKLGDSQEICIWVQGQPRYYLMVVQKYQEGMATVSVGIDISEWRYAQQESEKLKGENIRMSAELEVTQQLQKMLLPQPEELTAIEGLEIAAFMESAEEVGGDYYDVLNYDGVGTIAIGDVTGHGLESGILMVMTQTAVRTLKESRETDPLMFLDTLNRTIYHNVQRMKTDKNLTLAVLNYSQGEVRISGQHEEILVVRADGRIERVDTMDLGLPIGLDEDIREFIAQICVKLNSGDGIVVYTDGITEAQNRQKHRYGVNQLCDIISQHWHQSVEEIQQAAIADVRAYIDGQKTLDDMTLVVIKQK
>NC_019693.1|WP_015151054.1|6282811_6283393_-|hypothetical-protein
MVMNEIFGEFIHDLPPGHDYLDIGFSANSRPIKDRWRNNLLSAYFVADYLTTFLPIDDNDPAAKRRQQDSKASVSYVANELLENTMKFHSPADEYPVRFGIHFIEGPEKIIVLMSRNTVTQEAGDRFKAFIQELLSSDPQELYIKRMEENNQDSGLGFLTMMIDYSAKLGWKFEPIPNHPNLMVATTLVQLIL
>NC_019693.1|WP_015151053.1|6282377_6282731_-|hypothetical-protein
MNFQEIKGEDYSVQYIPESVTVKLQGELSLTGSADYAPIAQLLSEIAELNPPTITLDLKKLEFLNSSGISMLSKFAISVRKKNQIKLAVVGSDEIAWQRKSLQNLLKLCPNLQLTLE
>NC_019693.1|WP_015151052.1|6279649_6282244_+|M1-family-metallopeptidase
MSNQYSYFDTENNAHKTFELPGAKPHYNPDRPGQVEHICLDLALDLDHQSYQGTCSIRLMPVRTGIDRLTLDAVNLNIQEVTVSDTPQPFDYDGERLEIHLTQPTTAEHPLTLVVTYGVEQPQRGLYFIAPDAHYPNKSVQVWTQGEDEDSRFWFPCFDYPGQLATSEIRVRVPKPYLAISNGELISTEEEGNDKIYHWFQKQVHPTYLMTLAVGDFAEICDEWNGKPVVYYVAKSREEDARRSMGKTPRMMEYFSEAFGYAYPYPKYAQVCVEDFIFGGMENTSTTLLTDRCLLDERAHLDNQRTESLVAHELAHQWFGDLVVIKHWSHAWIKEGMASYSEVLWTHEEYGPEDAAYYLLNEARSYLNEDKTRYRRPIVTHVYREAIELYDRHLYEKGACVYHMIRAELGDELFFKAVHTFVNDNAHQTVETVDLLRAIEKATGRNLMFLFDQYVYRGGHPDYKVSYNWDGDSKLAKVTITQSHVKTTGEKGNEKELFDLKIPVGFGYKNGESLKTFTVRVNQREQSFYFPLEEKPHYISFDVGNATLKTVQLEYPVAELKAQLQDDPDPVSRIYAAVALAKKGGLEAVKALGSALKTERFWGVRVEVAKQLGKIKLDQAFEPLTVGLEDEDARVRYAVVETLAHHKTPESYQAIAQVLEQGDASYNVEAAAARAVASICAGKRNEPLDEGDAIARLQKVLQERAGWNEVVRSGAISGLSKLKTSEDALNIILDYTANGVPQPLRLAAIRAIGGISTGQTPGNLERILDRLSDLSAETFFLTQVAVASALGQMETPKAVGILQSLADATPDGRVRRVAEEAVAKVEKNIGSDKAVKQLRHELDQIKKENQELRSRLENLEAKTK
>NC_019693.1|WP_015151051.1|6278444_6279449_-|N-acetylglucosamine-kinase
MSELVRDPEFNDSTDWVLGIDGGGTKTVCLVMDETGTIAGRGEAGPSNYQTIGLAAAGKSISQAIASAVNALPGIEIAGIGVGLAGVGRPTDVQVVQGLVAGLYQEGPLPIRWNLHSEGVVVTHDCEIALVGGTGSASGVAIVAGTGSIAYGCNSQGESKRAGGWGYRFGDEGSGYQIAIAGLKAAVRSHDGRGPKTLLRDSFLDYLNLNQLEDLIEVIYRRGWGVTEIAALSPLVDRAAAAGDAIATQILEDAATELVLMTQTVASALFTPDQAFEVVTIGGVWRSVCHLGDRFRDSLCTQFPAVQVISPRHEPAYGAGLLALERLGKGVLSL
>NC_019693.1|WP_015151050.1|6276263_6278285_-|N-6-DNA-methylase
MNLERDSKAVYRQIRNYLVGRFLGATRDETLLQETIKCLFCKLYFQQNPALFDPIHDHSNVEAIARRYHKSFAQLGLLLPTLFPPEQRLLLDSQSLAQIDTLLNTANLDTSVQDPFGEIYEVFMGSQIRGQDGQFFTPLNAIALLVTLVNPLPGERIIDPACGAGGFLSMTARHLKAAGASLQQILSTVFGLDKDHYLAGLAATRLSLLSLKSAQVFCADSLAWKRESLAPTFFTNFDKTSSNSQPLPFPTQIGEFDIVLTNPPFGSRIVAASPQVQATFELGYRWRLQKNSQSFEKLPKLQPSVPPQVLFVERCLSLVRPGGRIGMVVPESLISSKTYRYVVDYIQSKCIIKAVIGMPDVLFKISGKGGTHTKTCLLLLQKKSGKIAEDESNPSIFMAEAQWCGRDSRGQPIDRDDLPEIAAQYRDYEQGLLTKPSQLGYWMTGDRIQNGILAPHYYNPAAISELFYLQDSHDFISMGELISGGMIEVSSGDEVGKLAYGTGNIPFVRTSDISNWEIKADPKHSVSEEIYQSLVEKQDLREGDILMVRDGTYLIGTCALITADDTRILFQSHFYKLRVRETCPFCCYLLLAALSSVPVQKQILAKRLTQDIIDSLGNRIQELILPIPKDKARQEKIAQMVKQTIQHRIEARKLARQSCLELVAGCNPDLWQT
>NC_019693.1|WP_015151049.1|6275328_6276276_-|hypothetical-protein
MADMMPLTPQETSDGSFTFYSAEFGELFHSYHGARQEAQCKFVEPTELAQKAQNPQVRVLDLCYGLGYNTASALETIWSINPACLVEWVGLELDAAIPQAAIAQGLLKGWHSPIPELLTGLVSPEADFESTIPRIQPSVLEWPGESRCARTLTTPQFQGTLWLGDARNTIQQVVNQGFQADAIFLDPFSPPHCPQLWTVEFLGWVARCLSPTGRLATYSCSAAVRTALMAGGLKVGATAPVGRRSPGTVASFGDRDLPPLSPQEQEHLQTRAAIPYRDPNLSDSAEEIRLRRQQEQVLSPLEPTASWKKRWTSIA
>NC_019693.1|WP_156823959.1|6273927_6275019_-|response-regulator
MEILRARCLSVNFLDAEQSKILVVDDHPASRMTAVALLSVEGYEILEADSGPSALACVKETQPDLILLDVMMPGMDGFEVCRHLKQDEQTRLIPIIFVTALNDRRSRIRGIEAGGDDFLTKPFDHLELAARVKSLVRQKRLNEDLDHAEQVLFSIARTVESRDPNTGDHCERLVSRGQAFGEFLHLSRNEIRDLMWGGYLHDIGKVGIPDAVLLKTGKLTAQEWEIMKQHVVIGEKICLPLRTMRGVRPLIRHHHERWDGTGYPDGLVGDEIPYIAQVFQVVDIYDALTSERPYKQAFTSEKALEIIAEETAKGWRNPQLVEQFTTFIRTTEMGTPARAVNRLQLIESDEPAAIAGSWRIANG
>NC_019693.1|WP_015151047.1|6272444_6273803_-|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU
MVAVAILAAGRGTRMKSDLPKVLHPLGGRSLVERVLDSLSAIQPSRRLIIVGYRGELVQNELIQRFDNIEFVEQTEQLGTGHAVQQVIPYLKDFTGDLLVLNGDVPLLRPETIKRLLNTHKEQGNAATILTAQLPDPKGYGRVFCDNDNLLKEIVEDRDCTLAQKQNQRINAGVYCFHWPDLAQVLPQLKAENDQAEYYLTDAVNYLNPVRILDVEDYQEILGINDRKQLSTAYQILQTRVKDDWMAAGVTLIDPDSITIDDTVTLAPGAIIEPQTHLRGQTTIGSGSRIGPGTLIENSQIGDQVTVLYSVITDSTVAAGTRVGPYAHLRGQAQVGEGCRIGNFVELKNTKLGNRSNVSHLSYLGDTTTGDRVNIGAGTITANYDGVNKHPTEIGSGTKTGSNSVLVAPVKLGANVTIAAGSTITEDVEDDSLAIARARQVAKKGWKLKAKE
>NC_019693.1|WP_015151057.1|6287118_6287949_-|sulfurtransferase
MTQTHPIISAEWLFQHLDDPQIAIADCRFSLADPELGQQQYLHHHIPGAHYLHLNRDLSSPVQRHGGRHPLPDSELFAQKLGSIGVTSPDVLLVIYDDSRFAFAARLWWLMRYLGHDRVAILEGGFKGWQTAGYPVTDAIPRPSEGTFIPQIRTDRLVDIETVKTRSPLPEVALIDSRERDRYLGNHEPIDPIAGHIPGALNYPWQEVTDENAQVRPQNDQVQRWADIAGSDEIIVYCGSGVTACVNLLSLEIAGIPNAKLYAGSWSDWCSYQVAD
>NC_019693.1|WP_083896819.1|6288146_6288785_+|CDP-alcohol-phosphatidyltransferase-family-protein
MKIQSKGLVVVETWARDRTKFIVEPIAKGIAKLGISANTITLLSLLLNILAAGVIANDQPLWGGLLMGLIAMPLDAIDGPVARLLNQQNAFGAFFDSVLDRFSEGAILIGITILLIHRQEYPSVPICLLALLGSQMVSYTRARAEGLKIECKVGWFPRLPRVIVMAVGLILDQLPVALSVLAIASLLTSLQRIIHVYRVTHPVEDSSEMRIS
>NC_019693.1|WP_015151059.1|6288844_6289717_-|sugar-kinase
MFDVCVIGHVTQDRIKIDGKIVQKMAGGTAIYTAIALKTLGLNVAVLTKTSRPDRSHLLEELKNRGIAVFWSESPETTQFENSYQRDRRDSRKQRVQAVASPFTPSDLGPIQARIFHLGALTNQEMSLEFLQAVFATQALISLDGQGFLRQVINHTVKAMDWTEKLPGLAGVDILKVDIQEAQLLSGKPAIEPAAIALNQWGVREVLITAGSQGSWVYQSGILEQIPAFPPTTSVDPTGCGDTYIAGYLYSRFTGEPSSHAARFAAQVATRKLENFGPLREWQTGESIPG
>NC_019693.1|WP_015151060.1|6289836_6290940_-|inositol-3-phosphate-synthase
MEKIKLAIVGVGNCASSLVQGIYFYKDKTSEEAIGLMHWDIGGYKPNDIDVVAAFDIDRRKVGQDVSQAIFAEPNCTMVFCQDIPEIGTKVSMGRMLDGVSEHLVNYADKYTFVPSDAPEPTRDDVIAILKESGAHVLVNYLPVGSEEATSFYAECCLEAGVAFVNCIPVFIASNQLWADKFESRNIPIVGDDIKSQLGATIVHRMISDLAKKRGVKIERTYQLNTAGNTDFLNMLNRTRLKSKKESKTEAVQSVCETRLEDENIHVGPSDYVPWQKDNKVCFIRVEGKLFGDVPMNIEMRLSVEDSPNSAGVAIDAIRCCKLALDRGKGGVLFSPSSYFMKHPPKQYPDGDAYRMTEEFINGFREY
>NC_019693.1|WP_015151061.1|6291715_6292864_+|histidinol-phosphate-transaminase
MLSFIRSDLAQLIAYTPHPGGAIDSPGGKPAQIDRVDTNESPYDLPAALKEKLAWTYQQEIETNRYPDGSHAPLKQAIAEYVNESAQLQGSLITASHISLGNGSDELIRSLLIATCLGGEGSVLVAHPTFSMYGILAQTLGIPVVEVGRNETNFEIDIPGAQAAVANTQNPPVRVVFVVHPNSPTANALTPAELDWIRSLPPHILVAIDEAYFEFSQTSVVSELLQHPNWVIMRTFSKAFRLAALRVGYAIAHPELTATLEKVRLPYNLPAFSQIAASVAIGHRQELLRAIPEILTERDRLLERLQSFQKFRLWPSAANFIYLRPNLQDQWAIGPTLSRITEELKAQGTLIRHTGGGLRITVGTPEENQRTLSRLQEFNFGD
>NC_019693.1|WP_044197855.1|6293581_6294043_-|hypothetical-protein
MKYAHSAQILTQLNSGQLFVVDSRRRCGLIVYKRFHAEFVGPGAAVGGIFDIECQQTIPVGDLVLLYPESYEERQKAFAIRRHWIRLMEQLTEQPVSLHRTQMLLTQFQHYFDRETVIRLPDEAIARLVGVLPQTVRTIRRLEQKSPVTVAVG
>NC_019693.1|WP_015151063.1|6294759_6295410_-|GNAT-family-N-acetyltransferase
MNSSFTSPTHREPPASEPSSGGASGFSIRAAQSPDLSSLAEILVDSFHSREGLGGWLYPILRLGIYEDLRVRLRSNSSHCICLVAIDPQPEPPSCYESARDSPSGNCVIVGTVEMALRCINPWTLGMTQFPYLSNLAIGDPYRRQGCASQLLQSCEGIALDWGFQDLYLHVLENNRPARRLYYKEGYRIHSIESGLGSWCFGQPKRMLLHKALDRR
>NC_019693.1|WP_015151064.1|6295582_6298078_+|GAF-domain-containing-protein
MNADIFPFGPHEVGSANRTSRRMAIAELLGRQTDWHLGGNEAENAAWTAGWLDCLEFLGQIDRGIVAKVKQLCCEKRQFSREEISTSVCLTKNTAGEGNGEAENVQSLSATPGTVQSPKAPRNFSEKNRDRRKQPPGEGEQVLSAQRLNAIAKAIHGSLDETEIYQAIVQQMCDVFEADCGGLILHDLQEQTLIEMAVYHPLEASPESPLRHREIRAPLRVEGLKEWNTLRSQKSPWVVGDIATTGMPEVERLLLRGSGLQSTLMVPILSQNEAIATVYLSYTEAAHRWQPSELKFAEMVAQQAAVALGNVRHYIQAKKHVQREQVLNRIAGRIRTSLDLDRTIETALSELLTLTQADLILFSTPTSLIESIHHLCRSLRITHRVCRPSQSTSLDEHPLDVGIEIKLFQFEAGLIQSLLGQEVTAISNTQSSDFGERDQALFHQLQIGSLLSIPIWHRETLLGHVSAIKPQSYDWNEDEISAMESISLHLGIAITQAQLYQRTQDQARQARSQAQKLRKALDEKTELIASLHDTQFQLVQSEKMSSLGQLVAGVAHEINNPINFIYGNLPHIANYSKEIVALLERYREHLNPVPQSIAEFEAEIDIHFIQTDLTQILRSMKEGSERVREIVLTLRNFSRLDQAEVKWVDIHEGIDSSLILLAHRLHNIEVVKSYGDIPRLCCYPGQLNQVFMNLFSNAIDAIELPDRGGNAATFPVNHLGSGQITITTTVIAQTDLPLDTLLPSHPPYLPTGEWVQIRIRDTGCGILPQHQTKIFDPFFTTKPVGSGKGLGLSIAYKIIVDRHHGRLTFENLPEGGCEFIIELPVISQDPI
>NC_019693.1|WP_015151065.1|6298304_6298559_-|hypothetical-protein
MYTTPPDPDGLEVRGNTSLASCTLADLPLELHPDGKIDEGDRPFGWVGIIGNNDDILLVTVGSCMRDFTDSKSRSFVPVAVSVS
>NC_019693.1|WP_015151066.1|6298686_6302259_+|response-regulator
MSIETDSKPKLLVVDDEPDNLDLLYRTFYRNYQVFTAENASQALELLAQEGDVAVIISDQRMPQMSGTELLSLTATQYPDAIRIILTAYTDVEDLVDAINEGKVFKYVTKPWDADELKALVAQALDTHNVLKARTRELCRTLRQESLLNAITNTIRSRTTEAQILQTIVDTLGQMFEVSYCILRPYQDGRFIDEWFMYQKRELGTIKSNGQGPKLPLAPSGPISEPLGLAQTVWETHDIEVINDVETDERLQGKTPQLQQRRQMLKTADIRSCLVVPLMFRLELMAVLALHQCGSGREWQDDEVQLVFMVADQAVLSLSQARAYEQVQALAQREALVNTITTAIRSSLNPKDIFAAIAQQLGQALQADGCALSLWTEEDEYVQCVGLYDAALQAVEASEGEQLEDEGSERVGRFSPSAESALAVKGESPQNSGELPRSVVPIAGNPVLQELLTTRAPVVVDDLEEQPEWNVMDLPLRSPARALLLVPLISDGEIIGSITLRQVRAPRRWHPSEIELAQAVAAQGAIAVHQSRLYQKTRQQAERLLELNRLKTEFFQNISHEFRTPLTLMMGPLESAVEHHQDLPLEQAAIALRNTRRLLRLVNQLLDLQRLDAGRMQPTFRPCDLLSFVSQTVEIFRPYCEKKGIEITIDLQPCPSLYLDLEKFDKVLYNLLSNAMKFTASGGKIMVSLEQAGDYSLLQVKDTGIGIRTDQVPHLFERFRQAEGSANRSYEGSGLGLALAKELVELHGGTIAVESNYGEGSAFMVWLPLGNSHLPPDQIIEVPTGVEPARASVELADVQMEEDGVGFIGPGGMVQPAEPSTIHTLHPTIVVVDDNPDLRNYVSGILTKEGYRVILARNGAEGFDVVINHRPQLIVTDLMMPLVSGLDMIQMIREDESLRGTPIILLTAKVNEDTRIEGAEKGADAYLAKPFNDRELLAEVRNLLALKENERRVAQLNTYLTESVLRRFLPPSMVQKAASGELSLDLRPEPRLITILFSDIVGFTQLANTLRSRRVAEVLNQYLTEMTQAVFDNGGTVDKFVGDAIVAMFGAPEDLTPNEQVRRAIATARQMLQALDRLNENWEEQGLPRVQFRCGIHQGTAVVGMFGGNLRSDYTAIGPSVNIASRLQEAADPGTILVSAAVADYLHDDEIVKFASLQLKGIDETVLTFMVHRHSRGTDGEESQAEGSNL

Crispr_ID: NC_019693_69

• CRISPR_ID: NC_019693_69
• CRISPR_location: 6550602-6550678
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_69

Consensus_repeat	Method
GCCCCTACGTCACATAACGATTGAGC	CRISPRCasFinder

spacers of NC_019693_69

>69.1|6550628|25|NC_019693|CRISPRCasFinder
CACCAATTCAGGGCGCAAGCATTGC

CRISPR arrays and Neighbor proteins around NC_019693_69

CRISPR arrays

The CRISPR arrays of NC_019693_69

>merge|NC_019693|69|6550602-6550678|CRISPRCasFinder
GCCCCTACGTCACATAACGATTGAGCCACCAATTCAGGGCGCAAGCATTGCGCCCCTACGTCACATAACGATTGAGC

>NC_019693|69|67|6550602-6550678|CRISPRCasFinder
GCCCCTACGTCACATAACGATTGAGC	CACCAATTCAGGGCGCAAGCATTGC
GCCCCTACGTCACATAACGATTGAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015151245.1|6543865_6544309_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151256.1|6553992_6554211_+|DUF2283-domain-containing-protein	unknown	unknown	gnl|CDD|378367
NC_019693.1|WP_015151259.1|6556359_6557997_-|protein-kinase-family-protein	unknown	unknown	gnl|CDD|270622
NC_019693.1|WP_015151258.1|6556036_6556252_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156824106.1|6552543_6552735_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151260.1|6558044_6559565_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156823966.1|6542666_6542843_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044195983.1|6554539_6555340_+|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl|CDD|371375
NC_019693.1|WP_015151244.1|6543543_6543726_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151249.1|6546701_6547106_-|response-regulator	unknown	unknown	gnl|CDD|381100
NC_019693.1|WP_044195980.1|6542816_6543350_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151252.1|6550740_6551016_-|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340594
NC_019693.1|WP_015151251.1|6550158_6550506_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151247.1|6545003_6545267_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151254.1|6552846_6553107_-|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340452
NC_019693.1|WP_015151250.1|6547279_6549880_+|DNA-topoisomerase-4-subunit-A	unknown	unknown	gnl|CDD|235502
NC_019693.1|WP_156824105.1|6545791_6546601_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_019693.1|WP_015151253.1|6551157_6552477_-|threonine-synthase	unknown	unknown	gnl|CDD|236065
NC_019693.1|WP_015151241.1|6542439_6542664_+|hypothetical-protein	unknown	unknown	gnl|CDD|239716
NC_019693.1|WP_044197935.1|6553231_6553810_+|plasmid-pRiA4b-ORF-3-family-protein	unknown	unknown	gnl|CDD|377943

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015151252.1|6550740_6551016_-|MoaD/ThiS-family-protein	gnl|CDD|340594	cd17074, Ubl_CysO_like, ubiquitin-like (Ubl) domain found in Mycobacterium tuberculosis CysO and similar proteins. CysO, also termed 9.5 kDa culture filtrate antigen cfp10A, together with CysM (Cysteine synthase M), forms a protein complex CysM-CysO that represents a new cysteine biosynthetic pathway in Mycobacterium tuberculosis. The replacement of the acetyl group of O-acetylserine by CysO thiocarboxylate to generate a protein-bound cysteine is catalyzed by CysM in a pyridoxal 5?-phosphate (PLP)-dependent manner. The family also includes QbsE that functions as the sulfide donor for the biosynthesis of thioquinolobactin in Pseudomonas fluorescens. A JAMM motif protein QbsD catalyzes removal of the carboxy-terminal dipeptide from QbsE. Both CysO and QbsE are similar to prokaryotic sulfur carrier proteins such as ThiS and MoaD, containing the beta-grasp ubiquitin-like fold.	2.17787e-52
NC_019693.1|WP_044195983.1|6554539_6555340_+|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl|CDD|371375	pfam11103, DUF2887, Protein of unknown function (DUF2887). This bacterial family of proteins has no known function. These proteins may be distantly related to the PD(D/E)XK superfamily.	1.87517e-101
NC_019693.1|WP_015151254.1|6552846_6553107_-|MoaD/ThiS-family-protein	gnl|CDD|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	1.52085e-24
NC_019693.1|WP_015151250.1|6547279_6549880_+|DNA-topoisomerase-4-subunit-A	gnl|CDD|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
NC_019693.1|WP_156824105.1|6545791_6546601_+|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	2.71101e-17
NC_019693.1|WP_015151253.1|6551157_6552477_-|threonine-synthase	gnl|CDD|236065	PRK07591, PRK07591, threonine synthase; Validated.	0
NC_019693.1|WP_015151241.1|6542439_6542664_+|hypothetical-protein	gnl|CDD|239716	cd03747, Ntn_PGA_like, Penicillin G acylase (PGA) belongs to a family of beta-lactam acylases that includes cephalosporin acylase (CA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and 7-aminocephalosporanic acid (7-ACA), which can be used to synthesize semi-synthetic penicillins and cephalosporins, respectively. While both PGA and CA have a conserved Ntn (N-terminal nucleophile) hydrolase fold and the structural similarity at their active sites is very high, their sequence similarity is low.	0.00367576
NC_019693.1|WP_015151259.1|6556359_6557997_-|protein-kinase-family-protein	gnl|CDD|270622	cd00180, PKc, Catalytic domain of Protein Kinases. PKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine or tyrosine residues on protein substrates. PKs make up a large family of serine/threonine kinases (STKs), protein tyrosine kinases (PTKs), and dual-specificity PKs that phosphorylate both serine/threonine and tyrosine residues of target proteins. Majority of protein phosphorylation occurs on serine residues while only 1% occurs on tyrosine residues. Protein phosphorylation is a mechanism by which a wide variety of cellular proteins, such as enzymes and membrane channels, are reversibly regulated in response to certain stimuli. PKs often function as components of signal transduction pathways in which one kinase activates a second kinase, which in turn, may act on other kinases; this sequential action transmits a signal from the cell surface to target proteins, which results in cellular responses. The PK family is one of the largest known protein families with more than 100 homologous yeast enzymes and more than 500 human proteins. A fraction of PK family members are pseudokinases that lack crucial residues for catalytic activity. The mutiplicity of kinases allows for specific regulation according to substrate, tissue distribution, and cellular localization. PKs regulate many cellular processes including proliferation, division, differentiation, motility, survival, metabolism, cell-cycle progression, cytoskeletal rearrangement, immunity, and neuronal functions. Many kinases are implicated in the development of various human diseases including different types of cancer. The PK family is part of a larger superfamily that includes the catalytic domains of RIO kinases, aminoglycoside phosphotransferase, choline kinase, phosphoinositide 3-kinase (PI3K), and actin-fragmin kinase.	9.43905e-10
NC_019693.1|WP_044197935.1|6553231_6553810_+|plasmid-pRiA4b-ORF-3-family-protein	gnl|CDD|377943	pfam07929, PRiA4_ORF3, Plasmid pRiA4b ORF-3-like protein. Members of this family are similar to the protein product of ORF-3 found on plasmid pRiA4 in the bacterium Agrobacterium rhizogenes. This plasmid is responsible for tumorigenesis at wound sites of plants infected by this bacterium, but the ORF-3 product does not seem to be involved in the pathogenetic process. Other proteins found in this family are annotated as being putative TnpR resolvases, but no further evidence was found to back this. Moreover, another member of this family is described as a probable lexA repressor and in fact carries a LexA DNA binding domain (pfam01726), but no references were found to expand on this.	4.23859e-95
NC_019693.1|WP_015151249.1|6546701_6547106_-|response-regulator	gnl|CDD|381100	cd17548, REC_DivK-like, phosphoacceptor receiver (REC) domain of DivK and similar proteins. Caulobacter crescentus DivK is an essential response regulator that is involved in the complex phosphorelay pathways controlling both cell division and motility. It localizes cell cycle regulators to specific poles of the cell during division. DivK contains a stand-alone REC domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.51609e-32
NC_019693.1|WP_015151256.1|6553992_6554211_+|DUF2283-domain-containing-protein	gnl|CDD|378367	pfam10049, DUF2283, Protein of unknown function (DUF2283). Members of this family of hypothetical bacterial proteins have no known function.	1.13622e-08

Protein sequences

>NC_019693.1|WP_015151251.1|6550158_6550506_+|hypothetical-protein
MKLNLMADTLQIELDFWEQFLAFSFEKILTIPISHIINASTAEPKSNWAEIRAPGTFLPGVIKAGTYYNPEGKEFWYVTREKDYLTLELRDEPFKRIVLTIDNALDWANRIQGEI
>NC_019693.1|WP_015151250.1|6547279_6549880_+|DNA-topoisomerase-4-subunit-A
MAKQLNLLSTGQVIPTALHVEMQQSYLEYAMSVIVGRALPDVRDGLKPVHRRIMYAMHELGLSPDRPYRKCARVVGDVLGKYHPHGDQSVYDAMVRMIQEFSSRYPLLAGHGNFGSVDNDPPAAMRYTETRLAEIGSDAMLQEIGEATVDFIGNFDNSQQEPIVLPAQLPMLVLNGSSGIAVGMATNVPPHNLGEVVDALIALIDNPDLSDEKLFTLIPGPDFPTGGEIIDTEGIRSAYTTGRGIIPLRGVARVEEIQGGRGKHRRQAIVVTELPYQVNKSAWIEKIADLVNHGRLDGISDLRDESDRDGIRVVIELKRETNPEVVLQHLYHQTALQNNFGAILLALVEAQPRQLSLRQMLQEFLTFREQTLNRLYTHELERTQQRLEIVEGLLKALNNLDALIEILRNAPDGTTAKVELQSELELTENQADAILGMPMRRITGLERQKLQDERDQLNTRRLELERLLGDRRELLKGLKKELRSLKKKYADPRRTRIYTVSPDRETVLVATPDSGEETSKTKSRKGKKAAIPEEVAPSLPLFATPPEPEETVLEFTRRGYVQRLSPSAYERQQQKQEENPEIQTLEAGADFVVETHVAFTDQDVLILTRDGKGFSIKVGDIPANKRGAKKTPFVSLFPPAVHGNPDAIATQFILSDYPETLDLIFLTERGRIKRLPLSEFANLTARGLTAVKLKEGDALAYANLATVGQDIAIATSGGRLLRFAIDDDNLPITSRASMPQQALRLGKGENLVGCVALSQSEKLLLVTKLGYGKRLPVELVRLAKPGDLGTQSMTFKNKTDGLVGMVAALPDAELKLLTSSDRFLRLPVKSVRSKRKDDAGDRLLKLEPKETLIYLSVSSPEPEQYV
>NC_019693.1|WP_015151249.1|6546701_6547106_-|response-regulator
MRTVLIVEDDLVNARVFSKILTKRGGLNVKHTENVEEVMQIAQAGEADVILMDVSLSRSVYQGKAVDGIKITQMLKADPKTSYLPIILVTAHAMAGDKESFLEQSGADGYISKPVVDHQEFVDQIAALLPKEEG
>NC_019693.1|WP_156824105.1|6545791_6546601_+|tetratricopeptide-repeat-protein
MGQALLPRTLQLDGTQLEQQGLFLAEEAAQLARFQQFELALARAELAAQLAPNAPQAWGILGSLYLQSKELPKGIAALERARSLDPKNHVVMFALGSAYFQQENYREAINSLQSGLKIQPDVPGALFDLGNAYYMTREYREAIAQYERAVAQDATFWPAINNIGLVEYEQGDINAAIQQWETALSIDSAAAEPMMAIAVAMYAQGNRERGLALGEEALRIDPRYGEVDFLVENLWGSRLLEDTKKFLETPRIQATLAQFMDVTPHNHSH
>NC_019693.1|WP_015151247.1|6545003_6545267_+|hypothetical-protein
MTQHLQILLPEETIRLIDQLTKSDDSADDALLKRSALINEAVKFYIAQKQRNSLKQQLQEGATRWAARDLGLADEWFDIEVEAAVAT
>NC_019693.1|WP_015151245.1|6543865_6544309_-|hypothetical-protein
MNHILIQDSAHHPQLFVWNGAIPANRLQTWLEKRNLKLPNDLIELWEMTGGGELFESETILSPFGDRNLGDDIDSVNELHHTQGMTQEYLLFHIGTGLSAVRLTDGRYVTLSDSYQELSKFLTLADWYRDELRSEYGSRYKLDALLV
>NC_019693.1|WP_015151244.1|6543543_6543726_-|hypothetical-protein
MKTLFEIKVAIGQLPEAEVRQLAQWLQDYLDDAWDKQMKEDLASGKLDKLITKAGQDLFR
>NC_019693.1|WP_044195980.1|6542816_6543350_-|hypothetical-protein
MITTLSLNRHRKARIWLGELPNLINPDYPFIERCLSGSASDLTHLQQGAIEMIIPSAGRALYGLLGGGFLPDRSGELVVKVAVSEKDELEMPESLASNFDTVYRGLPVEYADSVLSGIVDAGEILGSGLLLCNCAAHSPVGSSPRLFRQLALIWVRLIASQTESVSEEELTRLVSVG
>NC_019693.1|WP_156823966.1|6542666_6542843_+|hypothetical-protein
MKGASDEDECDRPLMLRLNPDDFTPKIGCLNWVSRVGCGYPVFEPAIALPLPYGNQSR
>NC_019693.1|WP_015151241.1|6542439_6542664_+|hypothetical-protein
MNTSEKTKAQRLSEALSDFDTVLEQDPQVQWYQMQPSQPDVTGAAPPGLPPAFQVQWLCLLLVHLVVLCFLRKK
>NC_019693.1|WP_015151252.1|6550740_6551016_-|MoaD/ThiS-family-protein
MSVKVLIPTPLQKFTSDKATVECSGSNVAELLDSLEANCPGIKERLCDEKGQLRRFLNVYVNEEDIRFLEGPDTPLKEGDEVSIVPAVAGG
>NC_019693.1|WP_015151253.1|6551157_6552477_-|threonine-synthase
MIQATELHTHSHDTPPNGATFDKLKCKECGAEYETKAIHVCELCFGPLEVKYNYDEIRRQVTRESIQAGPHSIWRYRPFLPVMTDTPIDVGTGMTPLVKSNRLARQLGMKNLYIKNDAVNMPTLSFKDRVVSVALTRAKELGFTTVSCASTGNLANSTAAIAAYAGLDCCVFIPSDLEAGKVLGTLIYNPTLMSVKGNYDQVNRLCSEVANTHGWGFVNINLRPYYSEGSKTLAYEVAEQLGWQLPDRIVAPLASGSLFTKIYKGFQEFIQVGLVDEKAVRFTGAQADGCSPIAAAFREGRDFIKPVKPNTVAKSIAIGNPADGVYALEIAHKTNGNIESVSDAEIIEGMKLLAETEGIFTETAGGTTIAVLKKSLEEGKIDPDETTVVYITGNGLKTQEAVQGYIGEPLTIEPKLESFERALERSRTLDRLEWQQALV
>NC_019693.1|WP_156824106.1|6552543_6552735_+|hypothetical-protein
MVTQGKILVNQSRLFWSGLVIGRWSLVVGHWSLVVGHWSLVIGHWCWWGGRVWVRNRVSSHNL
>NC_019693.1|WP_015151254.1|6552846_6553107_-|MoaD/ThiS-family-protein
MSEPPISVTVKLFAAYQEAYGVPELVLEFPPGTPVVAVRDRLIAEHPELDCWRDITRFGINLDFVDPQTPLQPGDEVVLIPPVSGG
>NC_019693.1|WP_044197935.1|6553231_6553810_+|plasmid-pRiA4b-ORF-3-family-protein
MPTRKKPQSIYQLKITLSGIRPPIWRRVQVSSDYTLGNLHQVIQVAMGWCDGHLHSFTIDGEDYGMPMDDDFGFGGMETNDETRVKLSKIIPGEKFKFSYLYDFGDSWDHQILVEKVLPPDPDATYPVCIKAKRACPPEDCGGPWGYPDLLEAIQNKKHPDHEEMLDWVGGSFDPEEVNLDQINAQFKKGFK
>NC_019693.1|WP_015151256.1|6553992_6554211_+|DUF2283-domain-containing-protein
MKETRFLKYKGQVKIWYDQDADFLEVIFSETPGFMREPDDDSIMERIDEAGNIIGFSVMNVSGFSLKRHRLR
>NC_019693.1|WP_044195983.1|6554539_6555340_+|Rpn-family-recombination-promoting-nuclease/putative-transposase
MKTDSLFYQIFKQFPASFFELIHRSASDAAAYQFTSVELKQVAFRIDGVFLPKQEESTQPFYLVEVQFQPDDSLYYRIFGELFLYLKQNQPPHPWRVVVIYPNRRIEREQELQFSEMLELSRVSRIYLDELNDSNESLGIQVLQLVIQDTESAATERAKQLIARSQSQITSDEVRRQFIELIETIIVYKLPQKSREEIEAMLGLSELRQTKVYQEAFSEGKIEGKIEAIPKMIQKGISLEDIANILDLPLETVQQNIPNSEGKSST
>NC_019693.1|WP_015151258.1|6556036_6556252_+|hypothetical-protein
MTQIVSLQQAIECVKSLSLEKQYLLIKLIQKRRIEQRRQEIATHATQTLQSLKAGTAKRGTLADLRADLLG
>NC_019693.1|WP_015151259.1|6556359_6557997_-|protein-kinase-family-protein
MLYPSLSDYGAAIRNPHIAFRKKDPKTKQDIVLDPVLVKGHPIEITGPNGMKSPWSAAGGFAVAFKYKTPLPNQVWAVRCFKKTASDVNLHYQNISKNLQSLKGNSCGSYFVDFLFLDEGIRVNGKCYPTVRMEWVEGKDLKTYIRDNLKNPQKLRDLAMAWIDLSKTLFNQGIAHGDLQHGNILVIDTGISSLKLIDYDSLYFCQDGGCKDDFIKGIPDYQHPLRGSLSKQCREIDFFSQLVIYLSIIALAESPSLWNRFKLDQSEHLLFSKNDFSSPDKPNNIFEALANLSSPLQDIAWEMKHICKLTDFKAIPSLETVLTKAGILSQPVGWFPQPINPTTNQSYFPGASPAPVNSTPPTPPQPVAWNPSSSSPPISPQPTPSQPVAWNPSSSSPPISPQPTPSQPVAWNPIPTSSSSNSTQQYNPQTVSGNTRKNQNVNPAHPSQSTSVPWQVQQPSPPKPQPVNPGKKVPPTPKPQPVPTIPAIHSPSSPTKRSRNVRSWIVAVIYVTLAGAFGTFSYSWYQNNKETIENYQFNWESPFNK
>NC_019693.1|WP_015151260.1|6558044_6559565_-|hypothetical-protein
MKDRIFYFSIPKVGERESDIQDAFSASPDGRLTAISDGASSSLFPKEWADLLVKNFCSSSHFADSRGTSWQDWLKPLQQEWREFYLNQHSRLPWYAKGSENKTCASATFIGLKIDPPTQAGEKTWSVIAIGDSCLFQIDRNLENLSSFPLKCSDEFKSVTRAFNSLPESSYHPPTFHSGLYTDGDIFLLATDALSQWILTSYEQQDQRWKNLLSLQNKDEFYKFINQLRSDKQIHNDDTSLAIIKVNTIKQSSGHPPFQCQKGIIAKKTGIPLTPPNTIKTDNQQTLSGASQSNISRANPHHNRSNPQNYPLSSAIASSNRSSSSPNSDATTILYPEASSSSMLDANEQESSLSNSKILRKNDKSNRDREKRINILLLLLLISLTLNLFFLGGVIYFLINPINTPETQSNDQPLLTPETRSVKTVWIYSPVEYINPNRQSIIIPPNKKLSIYYSPENHLADSDYLEPGEYFYSETMFFTQNAAPSQAIASPNRNQPKYRWLKIKIP

Crispr_ID: NC_019693_70

• CRISPR_ID: NC_019693_70
• CRISPR_location: 6553857-6553965
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_70

Consensus_repeat	Method
CAGGACCAGAAACCGGGTTTCTAGC	CRISPRCasFinder

spacers of NC_019693_70

>70.1|6553882|59|NC_019693|CRISPRCasFinder
AAAATTTTGGCAATTTATTATACATTTTGTAAAGAAACCGGGTTTCTCAACCCTCAACC

CRISPR arrays and Neighbor proteins around NC_019693_70

CRISPR arrays

The CRISPR arrays of NC_019693_70

>merge|NC_019693|70|6553857-6553965|CRISPRCasFinder
CAGGACCAGAAACCGGGTTTCTAGCAAAATTTTGGCAATTTATTATACATTTTGTAAAGAAACCGGGTTTCTCAACCCTCAACCCAGGACCAGAAACCGGGTTTCTGCG

>NC_019693|70|68|6553857-6553965|CRISPRCasFinder
CAGGACCAGAAACCGGGTTTCTAGC	AAAATTTTGGCAATTTATTATACATTTTGTAAAGAAACCGGGTTTCTCAACCCTCAACC
CAGGACCAGAAACCGGGTTTCTGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015151250.1|6547279_6549880_+|DNA-topoisomerase-4-subunit-A	unknown	unknown	gnl|CDD|235502
NC_019693.1|WP_015151265.1|6563755_6564370_-|DnaJ-domain-containing-protein	unknown	unknown	gnl|CDD|365959
NC_019693.1|WP_015151258.1|6556036_6556252_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156824106.1|6552543_6552735_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151260.1|6558044_6559565_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151264.1|6563099_6563756_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NC_019693.1|WP_015151261.1|6559716_6560553_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|214621
NC_019693.1|WP_015151259.1|6556359_6557997_-|protein-kinase-family-protein	unknown	unknown	gnl|CDD|270622
NC_019693.1|WP_044197935.1|6553231_6553810_+|plasmid-pRiA4b-ORF-3-family-protein	unknown	unknown	gnl|CDD|377943
NC_019693.1|WP_015151249.1|6546701_6547106_-|response-regulator	unknown	unknown	gnl|CDD|381100
NC_019693.1|WP_015151256.1|6553992_6554211_+|DUF2283-domain-containing-protein	unknown	unknown	gnl|CDD|378367
NC_019693.1|WP_015151252.1|6550740_6551016_-|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340594
NC_019693.1|WP_015151251.1|6550158_6550506_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151247.1|6545003_6545267_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044195983.1|6554539_6555340_+|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl|CDD|371375
NC_019693.1|WP_015151253.1|6551157_6552477_-|threonine-synthase	unknown	unknown	gnl|CDD|236065
NC_019693.1|WP_156824105.1|6545791_6546601_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_019693.1|WP_015151254.1|6552846_6553107_-|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340452
NC_019693.1|WP_156824107.1|6560746_6562387_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379062
NC_019693.1|WP_015151263.1|6562421_6563075_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015151265.1|6563755_6564370_-|DnaJ-domain-containing-protein	gnl|CDD|365959	pfam00226, DnaJ, DnaJ domain. DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.	9.01818e-17
NC_019693.1|WP_015151264.1|6563099_6563756_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	1.34012e-15
NC_019693.1|WP_015151261.1|6559716_6560553_-|VWA-domain-containing-protein	gnl|CDD|214621	smart00327, VWA, von Willebrand factor (vWF) type A domain. VWA domains in extracellular eukaryotic proteins mediate adhesion via metal ion-dependent adhesion sites (MIDAS). Intracellular VWA domains and homologues in prokaryotes have recently been identified. The proposed VWA domains in integrin beta subunits have recently been substantiated using sequence-based methods.	3.88084e-07
NC_019693.1|WP_015151254.1|6552846_6553107_-|MoaD/ThiS-family-protein	gnl|CDD|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	1.52085e-24
NC_019693.1|WP_015151259.1|6556359_6557997_-|protein-kinase-family-protein	gnl|CDD|270622	cd00180, PKc, Catalytic domain of Protein Kinases. PKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine or tyrosine residues on protein substrates. PKs make up a large family of serine/threonine kinases (STKs), protein tyrosine kinases (PTKs), and dual-specificity PKs that phosphorylate both serine/threonine and tyrosine residues of target proteins. Majority of protein phosphorylation occurs on serine residues while only 1% occurs on tyrosine residues. Protein phosphorylation is a mechanism by which a wide variety of cellular proteins, such as enzymes and membrane channels, are reversibly regulated in response to certain stimuli. PKs often function as components of signal transduction pathways in which one kinase activates a second kinase, which in turn, may act on other kinases; this sequential action transmits a signal from the cell surface to target proteins, which results in cellular responses. The PK family is one of the largest known protein families with more than 100 homologous yeast enzymes and more than 500 human proteins. A fraction of PK family members are pseudokinases that lack crucial residues for catalytic activity. The mutiplicity of kinases allows for specific regulation according to substrate, tissue distribution, and cellular localization. PKs regulate many cellular processes including proliferation, division, differentiation, motility, survival, metabolism, cell-cycle progression, cytoskeletal rearrangement, immunity, and neuronal functions. Many kinases are implicated in the development of various human diseases including different types of cancer. The PK family is part of a larger superfamily that includes the catalytic domains of RIO kinases, aminoglycoside phosphotransferase, choline kinase, phosphoinositide 3-kinase (PI3K), and actin-fragmin kinase.	9.43905e-10
NC_019693.1|WP_044197935.1|6553231_6553810_+|plasmid-pRiA4b-ORF-3-family-protein	gnl|CDD|377943	pfam07929, PRiA4_ORF3, Plasmid pRiA4b ORF-3-like protein. Members of this family are similar to the protein product of ORF-3 found on plasmid pRiA4 in the bacterium Agrobacterium rhizogenes. This plasmid is responsible for tumorigenesis at wound sites of plants infected by this bacterium, but the ORF-3 product does not seem to be involved in the pathogenetic process. Other proteins found in this family are annotated as being putative TnpR resolvases, but no further evidence was found to back this. Moreover, another member of this family is described as a probable lexA repressor and in fact carries a LexA DNA binding domain (pfam01726), but no references were found to expand on this.	4.23859e-95
NC_019693.1|WP_015151249.1|6546701_6547106_-|response-regulator	gnl|CDD|381100	cd17548, REC_DivK-like, phosphoacceptor receiver (REC) domain of DivK and similar proteins. Caulobacter crescentus DivK is an essential response regulator that is involved in the complex phosphorelay pathways controlling both cell division and motility. It localizes cell cycle regulators to specific poles of the cell during division. DivK contains a stand-alone REC domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.51609e-32
NC_019693.1|WP_015151256.1|6553992_6554211_+|DUF2283-domain-containing-protein	gnl|CDD|378367	pfam10049, DUF2283, Protein of unknown function (DUF2283). Members of this family of hypothetical bacterial proteins have no known function.	1.13622e-08
NC_019693.1|WP_015151252.1|6550740_6551016_-|MoaD/ThiS-family-protein	gnl|CDD|340594	cd17074, Ubl_CysO_like, ubiquitin-like (Ubl) domain found in Mycobacterium tuberculosis CysO and similar proteins. CysO, also termed 9.5 kDa culture filtrate antigen cfp10A, together with CysM (Cysteine synthase M), forms a protein complex CysM-CysO that represents a new cysteine biosynthetic pathway in Mycobacterium tuberculosis. The replacement of the acetyl group of O-acetylserine by CysO thiocarboxylate to generate a protein-bound cysteine is catalyzed by CysM in a pyridoxal 5?-phosphate (PLP)-dependent manner. The family also includes QbsE that functions as the sulfide donor for the biosynthesis of thioquinolobactin in Pseudomonas fluorescens. A JAMM motif protein QbsD catalyzes removal of the carboxy-terminal dipeptide from QbsE. Both CysO and QbsE are similar to prokaryotic sulfur carrier proteins such as ThiS and MoaD, containing the beta-grasp ubiquitin-like fold.	2.17787e-52
NC_019693.1|WP_044195983.1|6554539_6555340_+|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl|CDD|371375	pfam11103, DUF2887, Protein of unknown function (DUF2887). This bacterial family of proteins has no known function. These proteins may be distantly related to the PD(D/E)XK superfamily.	1.87517e-101
NC_019693.1|WP_015151253.1|6551157_6552477_-|threonine-synthase	gnl|CDD|236065	PRK07591, PRK07591, threonine synthase; Validated.	0
NC_019693.1|WP_156824105.1|6545791_6546601_+|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	2.71101e-17
NC_019693.1|WP_015151250.1|6547279_6549880_+|DNA-topoisomerase-4-subunit-A	gnl|CDD|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
NC_019693.1|WP_156824107.1|6560746_6562387_+|AAA-family-ATPase	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	1.89767e-07
NC_019693.1|WP_015151263.1|6562421_6563075_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	6.23752e-17

Protein sequences

>NC_019693.1|WP_044197935.1|6553231_6553810_+|plasmid-pRiA4b-ORF-3-family-protein
MPTRKKPQSIYQLKITLSGIRPPIWRRVQVSSDYTLGNLHQVIQVAMGWCDGHLHSFTIDGEDYGMPMDDDFGFGGMETNDETRVKLSKIIPGEKFKFSYLYDFGDSWDHQILVEKVLPPDPDATYPVCIKAKRACPPEDCGGPWGYPDLLEAIQNKKHPDHEEMLDWVGGSFDPEEVNLDQINAQFKKGFK
>NC_019693.1|WP_015151254.1|6552846_6553107_-|MoaD/ThiS-family-protein
MSEPPISVTVKLFAAYQEAYGVPELVLEFPPGTPVVAVRDRLIAEHPELDCWRDITRFGINLDFVDPQTPLQPGDEVVLIPPVSGG
>NC_019693.1|WP_156824106.1|6552543_6552735_+|hypothetical-protein
MVTQGKILVNQSRLFWSGLVIGRWSLVVGHWSLVVGHWSLVIGHWCWWGGRVWVRNRVSSHNL
>NC_019693.1|WP_015151253.1|6551157_6552477_-|threonine-synthase
MIQATELHTHSHDTPPNGATFDKLKCKECGAEYETKAIHVCELCFGPLEVKYNYDEIRRQVTRESIQAGPHSIWRYRPFLPVMTDTPIDVGTGMTPLVKSNRLARQLGMKNLYIKNDAVNMPTLSFKDRVVSVALTRAKELGFTTVSCASTGNLANSTAAIAAYAGLDCCVFIPSDLEAGKVLGTLIYNPTLMSVKGNYDQVNRLCSEVANTHGWGFVNINLRPYYSEGSKTLAYEVAEQLGWQLPDRIVAPLASGSLFTKIYKGFQEFIQVGLVDEKAVRFTGAQADGCSPIAAAFREGRDFIKPVKPNTVAKSIAIGNPADGVYALEIAHKTNGNIESVSDAEIIEGMKLLAETEGIFTETAGGTTIAVLKKSLEEGKIDPDETTVVYITGNGLKTQEAVQGYIGEPLTIEPKLESFERALERSRTLDRLEWQQALV
>NC_019693.1|WP_015151252.1|6550740_6551016_-|MoaD/ThiS-family-protein
MSVKVLIPTPLQKFTSDKATVECSGSNVAELLDSLEANCPGIKERLCDEKGQLRRFLNVYVNEEDIRFLEGPDTPLKEGDEVSIVPAVAGG
>NC_019693.1|WP_015151251.1|6550158_6550506_+|hypothetical-protein
MKLNLMADTLQIELDFWEQFLAFSFEKILTIPISHIINASTAEPKSNWAEIRAPGTFLPGVIKAGTYYNPEGKEFWYVTREKDYLTLELRDEPFKRIVLTIDNALDWANRIQGEI
>NC_019693.1|WP_015151250.1|6547279_6549880_+|DNA-topoisomerase-4-subunit-A
MAKQLNLLSTGQVIPTALHVEMQQSYLEYAMSVIVGRALPDVRDGLKPVHRRIMYAMHELGLSPDRPYRKCARVVGDVLGKYHPHGDQSVYDAMVRMIQEFSSRYPLLAGHGNFGSVDNDPPAAMRYTETRLAEIGSDAMLQEIGEATVDFIGNFDNSQQEPIVLPAQLPMLVLNGSSGIAVGMATNVPPHNLGEVVDALIALIDNPDLSDEKLFTLIPGPDFPTGGEIIDTEGIRSAYTTGRGIIPLRGVARVEEIQGGRGKHRRQAIVVTELPYQVNKSAWIEKIADLVNHGRLDGISDLRDESDRDGIRVVIELKRETNPEVVLQHLYHQTALQNNFGAILLALVEAQPRQLSLRQMLQEFLTFREQTLNRLYTHELERTQQRLEIVEGLLKALNNLDALIEILRNAPDGTTAKVELQSELELTENQADAILGMPMRRITGLERQKLQDERDQLNTRRLELERLLGDRRELLKGLKKELRSLKKKYADPRRTRIYTVSPDRETVLVATPDSGEETSKTKSRKGKKAAIPEEVAPSLPLFATPPEPEETVLEFTRRGYVQRLSPSAYERQQQKQEENPEIQTLEAGADFVVETHVAFTDQDVLILTRDGKGFSIKVGDIPANKRGAKKTPFVSLFPPAVHGNPDAIATQFILSDYPETLDLIFLTERGRIKRLPLSEFANLTARGLTAVKLKEGDALAYANLATVGQDIAIATSGGRLLRFAIDDDNLPITSRASMPQQALRLGKGENLVGCVALSQSEKLLLVTKLGYGKRLPVELVRLAKPGDLGTQSMTFKNKTDGLVGMVAALPDAELKLLTSSDRFLRLPVKSVRSKRKDDAGDRLLKLEPKETLIYLSVSSPEPEQYV
>NC_019693.1|WP_015151249.1|6546701_6547106_-|response-regulator
MRTVLIVEDDLVNARVFSKILTKRGGLNVKHTENVEEVMQIAQAGEADVILMDVSLSRSVYQGKAVDGIKITQMLKADPKTSYLPIILVTAHAMAGDKESFLEQSGADGYISKPVVDHQEFVDQIAALLPKEEG
>NC_019693.1|WP_156824105.1|6545791_6546601_+|tetratricopeptide-repeat-protein
MGQALLPRTLQLDGTQLEQQGLFLAEEAAQLARFQQFELALARAELAAQLAPNAPQAWGILGSLYLQSKELPKGIAALERARSLDPKNHVVMFALGSAYFQQENYREAINSLQSGLKIQPDVPGALFDLGNAYYMTREYREAIAQYERAVAQDATFWPAINNIGLVEYEQGDINAAIQQWETALSIDSAAAEPMMAIAVAMYAQGNRERGLALGEEALRIDPRYGEVDFLVENLWGSRLLEDTKKFLETPRIQATLAQFMDVTPHNHSH
>NC_019693.1|WP_015151247.1|6545003_6545267_+|hypothetical-protein
MTQHLQILLPEETIRLIDQLTKSDDSADDALLKRSALINEAVKFYIAQKQRNSLKQQLQEGATRWAARDLGLADEWFDIEVEAAVAT
>NC_019693.1|WP_015151256.1|6553992_6554211_+|DUF2283-domain-containing-protein
MKETRFLKYKGQVKIWYDQDADFLEVIFSETPGFMREPDDDSIMERIDEAGNIIGFSVMNVSGFSLKRHRLR
>NC_019693.1|WP_044195983.1|6554539_6555340_+|Rpn-family-recombination-promoting-nuclease/putative-transposase
MKTDSLFYQIFKQFPASFFELIHRSASDAAAYQFTSVELKQVAFRIDGVFLPKQEESTQPFYLVEVQFQPDDSLYYRIFGELFLYLKQNQPPHPWRVVVIYPNRRIEREQELQFSEMLELSRVSRIYLDELNDSNESLGIQVLQLVIQDTESAATERAKQLIARSQSQITSDEVRRQFIELIETIIVYKLPQKSREEIEAMLGLSELRQTKVYQEAFSEGKIEGKIEAIPKMIQKGISLEDIANILDLPLETVQQNIPNSEGKSST
>NC_019693.1|WP_015151258.1|6556036_6556252_+|hypothetical-protein
MTQIVSLQQAIECVKSLSLEKQYLLIKLIQKRRIEQRRQEIATHATQTLQSLKAGTAKRGTLADLRADLLG
>NC_019693.1|WP_015151259.1|6556359_6557997_-|protein-kinase-family-protein
MLYPSLSDYGAAIRNPHIAFRKKDPKTKQDIVLDPVLVKGHPIEITGPNGMKSPWSAAGGFAVAFKYKTPLPNQVWAVRCFKKTASDVNLHYQNISKNLQSLKGNSCGSYFVDFLFLDEGIRVNGKCYPTVRMEWVEGKDLKTYIRDNLKNPQKLRDLAMAWIDLSKTLFNQGIAHGDLQHGNILVIDTGISSLKLIDYDSLYFCQDGGCKDDFIKGIPDYQHPLRGSLSKQCREIDFFSQLVIYLSIIALAESPSLWNRFKLDQSEHLLFSKNDFSSPDKPNNIFEALANLSSPLQDIAWEMKHICKLTDFKAIPSLETVLTKAGILSQPVGWFPQPINPTTNQSYFPGASPAPVNSTPPTPPQPVAWNPSSSSPPISPQPTPSQPVAWNPSSSSPPISPQPTPSQPVAWNPIPTSSSSNSTQQYNPQTVSGNTRKNQNVNPAHPSQSTSVPWQVQQPSPPKPQPVNPGKKVPPTPKPQPVPTIPAIHSPSSPTKRSRNVRSWIVAVIYVTLAGAFGTFSYSWYQNNKETIENYQFNWESPFNK
>NC_019693.1|WP_015151260.1|6558044_6559565_-|hypothetical-protein
MKDRIFYFSIPKVGERESDIQDAFSASPDGRLTAISDGASSSLFPKEWADLLVKNFCSSSHFADSRGTSWQDWLKPLQQEWREFYLNQHSRLPWYAKGSENKTCASATFIGLKIDPPTQAGEKTWSVIAIGDSCLFQIDRNLENLSSFPLKCSDEFKSVTRAFNSLPESSYHPPTFHSGLYTDGDIFLLATDALSQWILTSYEQQDQRWKNLLSLQNKDEFYKFINQLRSDKQIHNDDTSLAIIKVNTIKQSSGHPPFQCQKGIIAKKTGIPLTPPNTIKTDNQQTLSGASQSNISRANPHHNRSNPQNYPLSSAIASSNRSSSSPNSDATTILYPEASSSSMLDANEQESSLSNSKILRKNDKSNRDREKRINILLLLLLISLTLNLFFLGGVIYFLINPINTPETQSNDQPLLTPETRSVKTVWIYSPVEYINPNRQSIIIPPNKKLSIYYSPENHLADSDYLEPGEYFYSETMFFTQNAAPSQAIASPNRNQPKYRWLKIKIP
>NC_019693.1|WP_015151261.1|6559716_6560553_-|VWA-domain-containing-protein
MPYSESLSSQNPGYIVILIDQSGSMSDRFGGGSKAEECAKAVNRVLKELGMACTVGTEVKNRCEISILSYGKSGNTIKNGFSGNLASQAVVTMPELVANCLRVDKVKRKVSDGAGGLVEIDDDFPIWIEPAAIGGTPMAEAFQEAYNLVSNWTQSHKSSFPPVVINITDGEPNDESKAKTAALQLSQTGTDDGNTLILNAHISTKMGGKVELPSSANGLPDSYAKFLFNISSELPSVMLDGARAVGFEPSNGARGFVYNADAEVMIRLLDIGTKQQLR
>NC_019693.1|WP_156824107.1|6560746_6562387_+|AAA-family-ATPase
MAGVLRASEEGLRIVNLARRNPGWNKNDRLWCEAAYTSKATLKRFWARRSIRRETFIDICKAVGIDNWEDVVERSDRQEKKPNLSHTTFPLPDKLPPVRNWVGRSQELNTLKSYLLNTDNSPTPTTAISIVGLAGIGKTTLASQLVRELHREATPFVAAAWECLLSPTGVALPCDRILDSLLLSLSNGEVTPAITAHEDCLTKTERLIQLLKNKPCLLLFDRLETVLTAGDARKAGYFAHEYSEYAWFFQQLLETEHQSKIIFISRECVAALPPTLTRELSLNGLDTEAALKLLQSFSLTATDEEFTQLAHRYQGHPKALELIASSIQNDECKGEVSTFFQVQDWLLTQEIESFLDETLSRLSDLALTCLCRISVYEPSEYPLTVMAIASQMPEVALYELKENIMRELKRRQLLCYTPDWLSYQLHPLVREKADRLLKQNPEQVQTAHRQAYQYFISIPLKPESAWTEIEDIKSLVRAHYHAYQGEDWEEAERVMSGLSECLQFGDAQLQDSFQDYRDRVQQNCPNLWHLSKQIPVLPADLQDHDS
>NC_019693.1|WP_015151263.1|6562421_6563075_-|Uma2-family-endonuclease
MTTTPKTQPPNEGRILLQNITWETYERLLVEMGDHRNTRVNYDRGVLEIITPLFEHENPNRLLAQVARTVAEELNVEILSAGSTTLNRPDLEKGSEPDSSFYIKNESLIRGKRTIDLKTDPPPDLVIEVDVTSSSIDREGIYAAMGVPEIWRCDRGLLKFLQLRSGNYVETKNSLAFPVLPVTEVAKFLEQSQTVGETTLLKAFRTWVREQIKVENL
>NC_019693.1|WP_015151264.1|6563099_6563756_-|Uma2-family-endonuclease
MTTTTPKSKPPTEGRVLLQNISWETYERLLNEMGDRRNIRLHYDRGLLEIMTPLFEHENPKRILEKFVDALADVLNIEILSAGSTTLNRPDLARGSEPDSGFYIQNEQQIKGKRTIDLKTDPPPDLVIEIDVTSSSIDREGIYAAMGVPEIWRCDRGVVKFLQRRSGNYVETEHSLAFPFLPVTEVAKFLEQSQTIGETTLVRTFRAWVREQIKSEAQ
>NC_019693.1|WP_015151265.1|6563755_6564370_-|DnaJ-domain-containing-protein
MTIEECYSVLGLKVGATLEEVKTSYRVLARQYHPDVNPGDGRSHDKFIQLNQAYHRLLEVAKPAAQVRQPSTPSPSPTPVTAPKTTVKTRVTRKEPEFRNNPRLTDLEQLLKQRGYLQLQGFLKAQRFPRAVALVDALAQRLPQDPEVRQWQAIAYQRWGRHAIAAGDLDKARIYLKKALTLDPHNRSLWMEVERDFRRLEQIF

Crispr_ID: NC_019693_71

• CRISPR_ID: NC_019693_71
• CRISPR_location: 6658457-6658544
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: Cas14u_CAS-V

Consensus repeat of NC_019693_71

Consensus_repeat	Method
TATGCAATACGCCCCTACAAGAAA	CRISPRCasFinder

spacers of NC_019693_71

>71.1|6658481|40|NC_019693|CRISPRCasFinder
CAAGGATGAGGCGGAATTCCATTGACGGTTAAAGAGGGCG

CRISPR arrays and Neighbor proteins around NC_019693_71

CRISPR arrays

The CRISPR arrays of NC_019693_71

>merge|NC_019693|71|6658457-6658544|CRISPRCasFinder
TATGCAATACGCCCCTACAAGAAACAAGGATGAGGCGGAATTCCATTGACGGTTAAAGAGGGCGTATGCAATACGCCCCTACAAGAAA

>NC_019693|71|69|6658457-6658544|CRISPRCasFinder
TATGCAATACGCCCCTACAAGAAA	CAAGGATGAGGCGGAATTCCATTGACGGTTAAAGAGGGCG
TATGCAATACGCCCCTACAAGAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015151326.1|6652676_6653876_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_019693.1|WP_015151325.1|6651695_6652478_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|226218
NC_019693.1|WP_015151328.1|6654890_6655889_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|226952
NC_019693.1|WP_052315805.1|6661268_6663185_-|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl|CDD|319781
NC_019693.1|WP_015151336.1|6668368_6669409_-|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|274362
NC_019693.1|WP_156823964.1|6659535_6660765_-|transposase	Cas14u_CAS-V	-	gnl|CDD|223747
NC_019693.1|WP_044195992.1|6645875_6646136_+|hypothetical-protein	unknown	unknown	gnl|CDD|226415
NC_019693.1|WP_083896824.1|6647884_6650980_+|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|226415
NC_019693.1|WP_015150029.1|6660619_6661213_-|IS607-family-transposase	unknown	unknown	gnl|CDD|225296
NC_019693.1|WP_044195998.1|6669685_6670030_-|hypothetical-protein	unknown	unknown	gnl|CDD|227726
NC_019693.1|WP_015151334.1|6666490_6667234_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_019693.1|WP_015151330.1|6657146_6658301_-|DNA-replication/repair-protein-RecF	unknown	unknown	gnl|CDD|234608
NC_019693.1|WP_015151333.1|6664370_6666086_+|ABC-ATPase-domain-containing-protein	unknown	unknown	gnl|CDD|370720
NC_019693.1|WP_044197974.1|6656009_6656843_-|hypothetical-protein	unknown	unknown	gnl|CDD|366166
NC_019693.1|WP_044197969.1|6645374_6645791_-|ISAs1-family-transposase	unknown	unknown	gnl|CDD|379382
NC_019693.1|WP_015151335.1|6667524_6668325_+|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl|CDD|235711
NC_019693.1|WP_015151332.1|6663878_6664100_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151327.1|6653971_6654760_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|226953
NC_019693.1|WP_015151324.1|6651096_6651390_+|membrane-protein-insertion-efficiency-factor-YidD	unknown	unknown	unknown
NC_019693.1|WP_015151338.1|6670391_6670973_-|hypothetical-protein	unknown	unknown	gnl|CDD|227672

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_156823964.1|6659535_6660765_-|transposase	Cas14u_CAS-V	-	5e-29	96.5	0.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015151326.1|6652676_6653876_+|sensor-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	9.19643e-50
NC_019693.1|WP_015151325.1|6651695_6652478_-|ABC-transporter-permease	gnl|CDD|226218	COG3694, COG3694, ABC-type uncharacterized transport system, permease component [General function prediction only].	1.51611e-90
NC_019693.1|WP_015151328.1|6654890_6655889_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|226952	COG4586, COG4586, ABC-type uncharacterized transport system, ATPase component [General function prediction only].	3.35102e-159
NC_019693.1|WP_052315805.1|6661268_6663185_-|HAD-IC-family-P-type-ATPase	gnl|CDD|319781	cd02089, P-type_ATPase_Ca_prok, prokaryotic P-type Ca(2+)-ATPase similar to Synechococcus elongatus sp. strain PCC 7942 PacL and Listeria monocytogenes LMCA1. Ca(2+) transport ATPase is a plasma membrane protein which pumps Ca(2+) ion out of the cytoplasm. This prokaryotic subfamily includes the Ca(2+)-ATPase Synechococcus elongatus PacL, Listeria monocytogenes Ca(2+)-ATPase 1 (LMCA1) which has a low Ca(2+) affinity and a high pH optimum (pH about 9) and may remove Ca(2+) from the microorganism in environmental conditions when e.g. stressed by high Ca(2+) and alkaline pH, and the Bacillus subtilis putative P-type Ca(2+)-transport ATPase encoded by the yloB gene, which is expressed during sporulation. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_019693.1|WP_015151336.1|6668368_6669409_-|two-component-sensor-histidine-kinase	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	4.21405e-66
NC_019693.1|WP_156823964.1|6659535_6660765_-|transposase	gnl|CDD|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.92441e-18
NC_019693.1|WP_044195992.1|6645875_6646136_+|hypothetical-protein	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	5.18394e-14
NC_019693.1|WP_083896824.1|6647884_6650980_+|SpoIIE-family-protein-phosphatase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	9.66676e-87
NC_019693.1|WP_015151338.1|6670391_6670973_-|hypothetical-protein	gnl|CDD|227672	COG5381, COG5381, Uncharacterized protein conserved in bacteria [Function unknown].	7.51118e-44
NC_019693.1|WP_044197969.1|6645374_6645791_-|ISAs1-family-transposase	gnl|CDD|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	4.65686e-19
NC_019693.1|WP_044195998.1|6669685_6670030_-|hypothetical-protein	gnl|CDD|227726	COG5439, COG5439, Uncharacterized conserved protein [Function unknown].	8.56882e-44
NC_019693.1|WP_015151334.1|6666490_6667234_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.53815e-18
NC_019693.1|WP_015151330.1|6657146_6658301_-|DNA-replication/repair-protein-RecF	gnl|CDD|234608	PRK00064, recF, recombination protein F; Reviewed.	2.33602e-144
NC_019693.1|WP_044197974.1|6656009_6656843_-|hypothetical-protein	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	0.00202093
NC_019693.1|WP_015150029.1|6660619_6661213_-|IS607-family-transposase	gnl|CDD|225296	COG2452, COG2452, Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair].	4.92999e-51
NC_019693.1|WP_015151335.1|6667524_6668325_+|uroporphyrinogen-III-C-methyltransferase	gnl|CDD|235711	PRK06136, PRK06136, uroporphyrinogen-III C-methyltransferase.	1.7755e-152
NC_019693.1|WP_015151327.1|6653971_6654760_-|ABC-transporter-permease	gnl|CDD|226953	COG4587, COG4587, ABC-type uncharacterized transport system, permease component [General function prediction only].	1.74693e-77
NC_019693.1|WP_015151333.1|6664370_6666086_+|ABC-ATPase-domain-containing-protein	gnl|CDD|370720	pfam09818, ABC_ATPase, Predicted ATPase of the ABC class. Members of this family include various bacterial predicted ABC class ATPases.	0

Protein sequences

>NC_019693.1|WP_015151330.1|6657146_6658301_-|DNA-replication/repair-protein-RecF
MFINQLHLRQFRNYREQEIELNAPKTILVGDNAQGKTNVLEALGLLSTLKSSRVSRDRDLVREGEPQGQIIGMVSREYRSVKLGVVLRRSGRRTVSVDEETCRRNVDFLGLLNVVQFSSLDLELVRSGPETRRSWLDGLLVQLEPIYAHILQQYNKVLKQRNALLKEIRSAEARGEKSHLGPEHQAQLGLWDAQLATIGVRVMQRRSRALERLVPIAETWHAAISGRVESLCIHYAPNVEGMQDKALRDRPQQAMQAFLEKLQSRAIAESFQGTTLVGPHRDDIEFTLNELPVKQFASQGQQRTLVLALKLAELKLIEEIVGEPPVLLLDDVLAELDPKRQNQLLEAIQDRFQTVIATTHLGGFEHDWINSAQILTVKAGEIFP
>NC_019693.1|WP_044197974.1|6656009_6656843_-|hypothetical-protein
MPSPPPRHPLDVIYEQFSKPQLTLILKKDEPSIYVRHTEGQVVRGNYQVEKVFEDKITGFYAEGRIPLLGNVPPVLVIRGYGSWYPLDGVLQDTPEVFIAHLDWQSKAAETQGAVAWITEKYQQGDRPDVIGESLGGKIAQQLGVKYGDRIRSVVTFNPLGVARKLAQSSPHPSVFHYFTLGERYAFWANQGEFIPGTILQISKRGTRSWKYRFTEWLIQRTPSPLEHFKSRHCLGRIIEIIERLVVQLILVYRHNGLIFTHRNPVVRVVNLKELLP
>NC_019693.1|WP_015151328.1|6654890_6655889_-|ATP-binding-cassette-domain-containing-protein
MSIIVAEHLSKVYPVAIKQPGMKGTLNHFFKRTYRNIEAVKDVSFQIQPGEVVGFLGPNGAGKTTTLKMLTGLIHPSSGRVEVAGHVPFQRKEAFLQKITLVMGQKQQLLWDLPALDSLRINGVVYGIPEKECRERIGQLTEMLSLEGKLNQPVRKLSLGERMKAELMAALLHNPDVLFLDEPTLGLDVNGQASVREFLREYNQRTGATILLTSHYMADITALCDRVILIYAGQLIYDGSLDGLVERFAPYREVQLELTQAIADPEKLRQQISQYGEVEEIAGQSVRLLVRRDTLTATVSQILIDFEILDLTVTEPPIEEVIGRVFTAGTIA
>NC_019693.1|WP_015151327.1|6653971_6654760_-|ABC-transporter-permease
MRRFFRIAPTLFSVHYAYMLEYRAEIVLWALSGTLPFILMGLWLEASQTGSFALNPVEFARYFLAAFIVRQFNVVWVVWEFEKEVVEGKLSMRLLQPLDPVWHHVAAHLAERGARLPFIAGLILIFFALYPDAFWLPNLGRFLLWIGVVILGFILRFLIQYTFSLLCFWIERANAIEQFWFLFYLFFSGMVAPLEVFPESVRQVVLWTPFPYMIHFPAALLVGLPVDVLPSLAIMCSWIAIFWIINRWLWRRGLRQYSGMGA
>NC_019693.1|WP_015151326.1|6652676_6653876_+|sensor-histidine-kinase
MNEFTKILRDKKATIVEQWIALVREDENISTADKLPYAAIRDTLPNIIDAIASLLDPPEEGEEADLLQSALEHGYIRAQQGYEPQEIAREYGLAREMMLSAIEEELERAKPQVIIGVIRLIDKAMDKVIGRCFHSYTEERLQELENLQSQLHFTNQELSRLVRTSKENLAHLAHELKTPLNSIIGYSDLFLRQQRKHFSEINDSTPNMEHIERVLRSGRQLLQLINDTLEISRYDSGKMPLNLIEIPPKNLICQTAEMLETMAREKQINLEVNCDQAPELIVTDPLRLQQVVTNLLSNAVRYTPEGTVRIECRISSKQEWQIVISDTGVGIDEKDQAEIFNPYYRVMSEHQTVLPNSTGLGLAIVSRLVKLLQGKIEVVSQLNVGSTFTVTFPLQIQSS
>NC_019693.1|WP_015151325.1|6651695_6652478_-|ABC-transporter-permease
MNRYLSTLALFWKTAIAAELEYRVNFAIAAFSSLGNLAGSWFALSLFYGADYNFAGWQWEEALVVLGVFTILQGFSSTFLAPNLNTIVKQVQEGTLDFVLLKPISSQFWLSGRTISLWGLPDIILGLLLIFYAGSQLNLPPVNYLVSFIPLLFGSISLYSLWFMLGAMSIWFVKIYNVTQVLRGLLEAGRFPMVAYPTAYRFFFTFIVPVAFLTTVPAESVLGRVELSWIAGAALLAIALFLASMAFWRFALRFYTSASS
>NC_019693.1|WP_015151324.1|6651096_6651390_+|membrane-protein-insertion-efficiency-factor-YidD
MQLTRVDGIARGLALEAIASYKIHLSPRKGFACAHRMLHQDESCSDYIYRMFSSENFLAAVAHSGERFRACANAHQSLKGTSKSGFGCIVLPCCLPL
>NC_019693.1|WP_083896824.1|6647884_6650980_+|SpoIIE-family-protein-phosphatase
MAEPAQAEELAHLNLKAGKKAKASAAYQPAFTYLVLGLNLLTTECWKSQYELTLALYQEATEAAYLSDDFQRMEEFANQVKIHAQSVIDKVQVYRALVLGYANQQLLPEAIRNGLEILQDLEIVLPEQPTPADIGQELGVTQTAWEGQEIEALIDRPEMTDPSKQAAMDLLFDVIHPAYDSNPALFTLCALKMVQLSLQYGNTPLSAQGYASYGIVLCGVVFDIDSGYQFAKLALKLLDRFQVKKIKSAVFFLVFYFSIHWKEHLKETLPPFLEGYQAGLENGDLLFAAFNAYGYSSYYYWIGKELPFVEREMAKYSEAIARINQNLILSYQNRYWQVILNWMGQSENPCLLVGEAYNETALLPMMIETSDRYGIGDLHLHKFILSYSFGEYGQALENAAIAEQYLDAMIATPAVAEFYFYQSLTHLALYPDSPESEQQHILEKVAANQEKMHLWAKQAPMNYQHKYELVEAERARISHQLSDARNAYDRAITLAKEQEYLNEEALAYELAARFYLSTDNTHLARYYLQDAHYAYQRWGAIAKVQHLETRYPQLLNLQTPKTPGSTITQGTFSSTSTTGSSSGDSLDLTTVLKASQAISSEIKLDQLLAQLLNLAIENAGAQKGILILSDNNQLKIVAAKLPDTEVQILESLPLTTGNLVPPSIINYVTRTQENVILADATGEGIFTREPYILQQQPQSVLCAPIINQGKLIGILYLENNLATGAFTPERIELLQIISAQAAISLENAQLYRTLEDKVIERTAQLAAANNEISALNEMLKSDNLRMSAELDITRKLQQKMLPRPQELQQIPTLEIAGFMEPADEVGGDYYDVLNYDGRVKIGIGDVTGHGLESGMIMVMVQTAVRTLLANNETDVVKFLSTINRTIYDNVERMQSDKNLTLALLDYTDGILRISGQHEEILIVRANGDIERVDTVDLGFPIGLVMEVNDFITQTQVQLNPGDGAVLYTDGITESVNVANEQYGLERLCEVVSQNWHRSAKEIQQVTIHNVREFIGQQKVFDDITIVVLKQR
>NC_019693.1|WP_044195992.1|6645875_6646136_+|hypothetical-protein
MDDGFILPLSENYTLIETDVEEVKEHLNIDYKFAHDRIQQAAYSLIPETEKSSVHWQIGQLLLQNTPVNEQEVKIFALGRRFSTRA
>NC_019693.1|WP_044197969.1|6645374_6645791_-|ISAs1-family-transposase
MSQIAIVQAFADLEDCRRQAGTRHKQSLCLALFTLGVAAGNRGFIAIGDWLKAYHDELLELFKPEKNRLPSYSTIRRTLLRIEQQRYSACLSRFFGIDPIESETIAVDGKVLLWYYEAINDEANVDSHPAIMLGSPKK
>NC_019693.1|WP_156823964.1|6659535_6660765_-|transposase
MRQVSVQNEKWLRTFSPSSTALAPDYTDCVNTKLRSKKIQIYPSPELNKVWRKWLAACRYCYNQAIALQKSGKRLSKLKLRNEVMQSDLPAWVKETPCHIRQNAIFDAHLAFSASSDARFRSCRDSSQAIKFNDANFSSGSWYPRLTKGLTFRVSEPIPKTCDQGTQLVFTKGRWFAVFPEPVAFIPTEATGVIALDPGVRTFITGFDGSRFLEFGSGDIGRITRLCQHLDDLMGRIAKEPNRSKRRRMKQAAQRMRTKIRNLVDEAHKQIAHYLTRNYSVIFLPTFETSNMVAKAKRKIRSKTARAMLTWAHYRFKLTLKHQAEITGTTVVDVTEEYTSKTCTHCGHVHSKLGGSKVFRCPECGVTLPRDWNGAFGIFLKALRDTASVTLTGNSAIVALSGNNRKNVA
>NC_019693.1|WP_015150029.1|6660619_6661213_-|IS607-family-transposase
MARYVKPKEAAQILGVHERTLRRWDENGSIETIRTPAGQRRYNVESYTAFSGSDKRKVVIYARVSSRAQQSDLNRQVAALSNLYPEAEVVSEIGGGLNFKRKKMLALLGQVLSGDVRMVVVAHKDRLARFGFDLFRWLCEQNRCELLVLNETSLSPEREMVEDILAILHCFSSRLYGLRKYKTQVKEDPDLPQPRAK
>NC_019693.1|WP_052315805.1|6661268_6663185_-|HAD-IC-family-P-type-ATPase
MSANSSGQYPLVPWHTLDIDKTLEKLQVDPTTGLSTAEAWERLQQYGPNELKETAGRSPWIILLDQFKNIMLLMLIGVAVISGFLALQQGEFPKDAVAIMLIVILNGVLGYLQETKAEKALAALKSLASPLVRVLRDGKLLEVASTEVVPGDLMFLEAGVQVAADAKLLEESNLQIRESALTGEAHSVEKDALIQLPENTSLGDRLNLVFCGTEVVKGRAKAIVIGTGMHTELGKIATLIQGVESEDTPLQQRMTQLGNVLVTGSLVLVAIVVIGGTLVQGMSAFNHLLEISLSMAVAIVPEGLPAVITVTLALGTQRMVKRHALIRKLPAVETLGSVTTICSDKTGTLTQNKMVVQGVETPSHSLTVTGEGYQPTGDFLAANGTKIGVGELGEYPELETLLLSSVQCNDAVLQYEKQDWEIVGDPTEGALLVLAGKLEFTGDRLSPQLPRVREFPFSSERKRMSVICQVSHPESEVITPESMPFVMFTKGSPELTLDCCTQILIGKQIQPLSVAQRQQVLDRNNDLAARGLRVLGFAYKPLTEQPPEGSEDQTERELVWLGMVGMLDAPRPEVREAVVKCRRAGIRPIMITGDHQLTAIAIAQDLGIAQQGSRVLIGQELEEMPQEELEREFNLIAD
>NC_019693.1|WP_015151332.1|6663878_6664100_+|hypothetical-protein
MNPNRDLQTAKPHQVNYRDWTILVFPGTDGYRPLCLASETEVLSDPKPYPTPEVAIAAGKRFIDRAIGHQEVA
>NC_019693.1|WP_015151333.1|6664370_6666086_+|ABC-ATPase-domain-containing-protein
MQYQQLRQQLNQLDGRSYKAYKDIQGRYEFPDFTLSIDYVQGDPFASPSKLSVRVPQSVAGFPQELYHSPSRNTALGDYLTREFTQAARQVSTRRGTGKSGQIAIAKVTQEVLERTCAFINSDEVEIRFTVGLPAQGRRILGHLAGEMLCDDIPRIVEKALFYRNLNVAQIRTQVETIEDADWLRDRLPEQNLIAFIANGAILPRRSGVDDRPLNPTEAIPFVSPDSLQVEFNCPNRGKITGMGIPSGITLIVGGGYHGKSTLLRAIEVGVYNHIPGDGREFVITDPGAMKIRAEDGRSVVGVDISPFINHLPQGRSTQQFSTANASGSTSQAANIMEALEAGTTVLLVDEDTAATNFMIRDRRMQALIAKEKEPITPFIDKIKSLTTLGVSTILVMGGSGDYFDVASRAVAMDNFVAYDVTDRAKAVAAEYATGRQSEGGEDFGAIANRVPIPNSLDPSSGKRDVRLKVRDVDEVRFGMEDIDLTAVEQIVDPGQLRAIAAAMVYGKDRYMDGRRSLREILDRVMADIDQQGLDVLTRFPEGDLVRFRPLELAAALNRLRTLQVSTPGKG
>NC_019693.1|WP_015151334.1|6666490_6667234_-|class-I-SAM-dependent-methyltransferase
MDFEAFFTVHCNLPREGPGSDEATREAIRRLPPLPRSPRVLDLGCGPGRQSLVLAQELNGSVIAVDLHEPFLQQLEVSAVQAGLGDRITIRHADMGALEDPPGSFDLIWSEGAIYLLGFANGLRLWRPLLRDGGLVGVSECSWIQDNPPREVREFWQVEYPEMMTIEDNLKTATEAGYEVFEPFILPRSHWWDEYLTPLSHRVKQLRASGNLTPALSQVLAETEREIDICDRYGDFFGYVFYLMKKP
>NC_019693.1|WP_015151335.1|6667524_6668325_+|uroporphyrinogen-III-C-methyltransferase
MVVQSYNSTRTKAKTLGKVYLVGAGPGDPGLLTIKGKTLLECADVVIYDALVSPQIIALINPHAEQINAGKRRGRHSLKQDETTQILIEQAQIHAVVVRLKGGDPFVFGRGGEEMEDLIAAGVAVEVVPGVTSGIAAPAYAGIPLTHRGYSSSVTFVTGHETVGKYRPQVNWQAIAQGSETIAVYMGVHNLPYITQELLNAGLSPDTPIALIRWGTRPDQEELIGTLETIVQRVEESGFEAPAIAVIGQVVNLHSILSTSRPAVFG
>NC_019693.1|WP_015151336.1|6668368_6669409_-|two-component-sensor-histidine-kinase
MWEETVTREQLLLEVQTLRRDVEMLKQEKNDLEILLENTTEHCDNIEAELLKAKEVAEVASRAKSEFLANMSHELRTPLNGILGYAQLMLEEEEDLTEQQRLDLTKIYQCGEHLLTLIADILDIAKIEACRLEIDAQEFNFPLFLKGIFDLFDMRSKQKGIEFTYERVTPLPSGIYTDQKRLRQILINLLGNAIKFTDSGWVAFKVGYAVNGQWCNSDRPPGCHPLPNSNGTPEELKAELENSGHRASRKIRFEIRDTGIGIPEEMLNEIFLPFHQVGDKSRMAEGTGLGLAISKKLVEMMGGELHVSSRLGEGSLFWMELELQELPEWVDHSNSLPLRIGNYPSK
>NC_019693.1|WP_044195998.1|6669685_6670030_-|hypothetical-protein
MEIKTDDYRLWYENETSTLTCQGSLRLNGMDEYDPIIQLLESAIDQEPETMILNLKGLEFLNSSGINVLSKFVIKVRQKKNVNLIVKGSKNLLWQGKSLKNLQRLMPSLELEWE
>NC_019693.1|WP_015151338.1|6670391_6670973_-|hypothetical-protein
MTEIFGDFIEDLPTGTEYLILGFSPASIPLKQRWRNNGLSADFLADYLTTFFPNSDEIASHSHKKAEIQCAVSYIANELLENAMKFSMETQGYPISIQLHLNSERIIFVTTNSICWEKVKGFQAFLKRLSTEDPIELYIEQLEKNAREGNSNASGVGFLSMINDYGAKIGWKFQDMNGEQKALAVTTMVQILL

Crispr_ID: NC_019693_72

• CRISPR_ID: NC_019693_72
• CRISPR_location: 6786377-6786468
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_72

Consensus_repeat	Method
TCCTTGATTGAGTCCTCTTGATGCAACCCCT	CRISPRCasFinder

spacers of NC_019693_72

>72.1|6786408|30|NC_019693|CRISPRCasFinder
AAAGGAGTTACTACAAACGTTCTTCGGGAT

CRISPR arrays and Neighbor proteins around NC_019693_72

CRISPR arrays

The CRISPR arrays of NC_019693_72

>merge|NC_019693|72|6786377-6786468|CRISPRCasFinder
TCCTTGATTGAGTCCTCTTGATGCAACCCCTAAAGGAGTTACTACAAACGTTCTTCGGGATTCCTTGATTGAGTCCTCTTGATGCAACGCCC

>NC_019693|72|70|6786377-6786468|CRISPRCasFinder
TCCTTGATTGAGTCCTCTTGATGCAACCCCT	AAAGGAGTTACTACAAACGTTCTTCGGGAT
TCCTTGATTGAGTCCTCTTGATGCAACGCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015151425.1|6776598_6777126_+|DUF1499-domain-containing-protein	unknown	unknown	gnl|CDD|377828
NC_019693.1|WP_156823977.1|6796260_6796665_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151424.1|6776120_6776540_+|DNA-sulfur-modification-protein-DndE	unknown	unknown	gnl|CDD|378074
NC_019693.1|WP_015151440.1|6800630_6801413_+|pyruvate-formate-lyase-activating-protein	unknown	unknown	gnl|CDD|131546
NC_019693.1|WP_015151435.1|6792687_6793713_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|223135
NC_019693.1|WP_015151442.1|6804604_6805036_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350229
NC_019693.1|WP_156823976.1|6781633_6781774_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044198020.1|6794008_6795628_-|phosphoenolpyruvate-carboxykinase-(ATP)	unknown	unknown	gnl|CDD|236471
NC_019693.1|WP_015151430.1|6783746_6786224_+|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|226702
NC_019693.1|WP_015151439.1|6798242_6800531_+|formate-C-acetyltransferase	unknown	unknown	gnl|CDD|153087
NC_019693.1|WP_015151441.1|6801804_6804561_+|bifunctional-acetate--CoA-ligase-family-protein/GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|223972
NC_019693.1|WP_156823978.1|6801391_6801574_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156824114.1|6796863_6797865_+|adenosine-deaminase-family-protein	unknown	unknown	gnl|CDD|236480
NC_019693.1|WP_015151434.1|6788333_6791717_-|response-regulator	unknown	unknown	gnl|CDD|274362
NC_019693.1|WP_015151427.1|6780220_6780763_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NC_019693.1|WP_044198014.1|6781782_6783231_+|bifunctional-orotidine-5'-phosphate-decarboxylase/orotate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|180119
NC_019693.1|WP_015151428.1|6780935_6781511_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151423.1|6774040_6776023_+|DNA-sulfur-modification-protein-DndD	unknown	unknown	gnl|CDD|274475
NC_019693.1|WP_015151426.1|6777244_6780190_+|DNA-phosphorothioation-associated-putative-methyltransferase	unknown	unknown	gnl|CDD|274979
NC_019693.1|WP_015151422.1|6772305_6773931_+|DNA-phosphorothioation-system-sulfurtransferase-DndC	unknown	unknown	gnl|CDD|235877

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015151425.1|6776598_6777126_+|DUF1499-domain-containing-protein	gnl|CDD|377828	pfam07386, DUF1499, Protein of unknown function (DUF1499). This family consists of several hypothetical bacterial and plant proteins of around 125 residues in length. The function of this family is unknown.	4.73493e-58
NC_019693.1|WP_015151424.1|6776120_6776540_+|DNA-sulfur-modification-protein-DndE	gnl|CDD|378074	pfam08870, DndE, DNA sulphur modification protein DndE. DndE is a small protein of 126 residues. It is a putative carboxylase homologous to NCAIR synthetase. It is encoded by an operon that is associated with a sulphur-based modification to DNA.	3.57457e-63
NC_019693.1|WP_015151440.1|6800630_6801413_+|pyruvate-formate-lyase-activating-protein	gnl|CDD|131546	TIGR02493, PFLA, pyruvate formate-lyase 1-activating enzyme. An iron-sulfur protein with a radical-SAM domain (pfam04055). A single glycine residue in EC 2.3.1.54, formate C-acetyltransferase (formate-pyruvate lyase), is oxidized to the corresponding radical by transfer of H from its CH2 to AdoMet with concomitant cleavage of the latter. The reaction requires Fe2+. The first stage is reduction of the AdoMet to give methionine and the 5'-deoxyadenosin-5-yl radical, which then abstracts a hydrogen radical from the glycine residue. [Energy metabolism, Anaerobic, Protein fate, Protein modification and repair].	1.09954e-124
NC_019693.1|WP_015151434.1|6788333_6791717_-|response-regulator	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	4.03539e-55
NC_019693.1|WP_015151442.1|6804604_6805036_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350229	cd09881, PIN_VapC4-5_FitB-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4 and VapC5, and Neisseria gonorrhoeae FitB and related proteins. This family includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This family belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.06377e-28
NC_019693.1|WP_015151430.1|6783746_6786224_+|GAF-domain-containing-protein	gnl|CDD|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	0
NC_019693.1|WP_044198020.1|6794008_6795628_-|phosphoenolpyruvate-carboxykinase-(ATP)	gnl|CDD|236471	PRK09344, PRK09344, phosphoenolpyruvate carboxykinase.	0
NC_019693.1|WP_015151439.1|6798242_6800531_+|formate-C-acetyltransferase	gnl|CDD|153087	cd01678, PFL1, Pyruvate formate lyase 1. Pyruvate formate lyase catalyzes a key step in anaerobic glycolysis, the conversion of pyruvate and CoenzymeA to formate and acetylCoA. The PFL mechanism involves an unusual radical cleavage of pyruvate in which two cysteines and one glycine form radicals that are required for catalysis. PFL has a ten-stranded alpha/beta barrel domain that is structurally similar to those of all three ribonucleotide reductase (RNR) classes as well as benzylsuccinate synthase and B12-independent glycerol dehydratase.	0
NC_019693.1|WP_015151441.1|6801804_6804561_+|bifunctional-acetate--CoA-ligase-family-protein/GNAT-family-N-acetyltransferase	gnl|CDD|223972	COG1042, COG1042, Acyl-CoA synthetase (NDP forming) [Energy production and conversion].	0
NC_019693.1|WP_156824114.1|6796863_6797865_+|adenosine-deaminase-family-protein	gnl|CDD|236480	PRK09358, PRK09358, adenosine deaminase; Provisional.	7.17265e-73
NC_019693.1|WP_015151435.1|6792687_6793713_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl|CDD|223135	COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism].	0
NC_019693.1|WP_015151427.1|6780220_6780763_+|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	1.02472e-34
NC_019693.1|WP_044198014.1|6781782_6783231_+|bifunctional-orotidine-5'-phosphate-decarboxylase/orotate-phosphoribosyltransferase	gnl|CDD|180119	PRK05500, PRK05500, bifunctional orotidine-5'-phosphate decarboxylase/orotate phosphoribosyltransferase.	0
NC_019693.1|WP_015151423.1|6774040_6776023_+|DNA-sulfur-modification-protein-DndD	gnl|CDD|274475	TIGR03185, DNA_S_dndD, DNA sulfur modification protein DndD. This model describes the DndB protein encoded by an operon associated with a sulfur-containing modification to DNA. The operon is sporadically distributed in bacteria, much like some restriction enzyme operons. DndD is described as a putative ATPase. The small number of examples known so far include species from among the Firmicutes, Actinomycetes, Proteobacteria, and Cyanobacteria. [DNA metabolism, Restriction/modification].	0
NC_019693.1|WP_015151426.1|6777244_6780190_+|DNA-phosphorothioation-associated-putative-methyltransferase	gnl|CDD|274979	TIGR04096, conserved_hypothetical_protein, DNA phosphorothioation-associated putative methyltransferase. Members of this protein family show distant local sequence similarity to a number of S-adenosyl-methionine-dependent methyltransferases. The family is identified by Partial Phylogenetic Profiling as closely tied to the DNA phosphorothioation system (dnd), and members are found adjacent to dnd genes in at least 13 species (Streptomyces lividans TK24, Shewanella frigidimarina NCIMB 400, Mycobacterium abscessus ATCC 19977, Nostoc punctiforme PCC 73102, Vibrio fischeri MJ11, etc.). The DNA phosphorothioation enables a novel form of restriction enzyme activity. Most members of this family appear in species with the DNA phosphorothioation system. [DNA metabolism, Restriction/modification].	0
NC_019693.1|WP_015151422.1|6772305_6773931_+|DNA-phosphorothioation-system-sulfurtransferase-DndC	gnl|CDD|235877	PRK06850, PRK06850, hypothetical protein; Provisional.	0

Protein sequences

>NC_019693.1|WP_015151430.1|6783746_6786224_+|GAF-domain-containing-protein
MMQPETVSWANYEREPIQSPGLIQPHGVLFVLSPDLKILQVSNNTVKFFGRPPERFLGKPLQTLLDAAQINVIHESINYQTLGSVNPLNITIHTDWETLYFDGIIHHSHSDCFILELEPALSPKTVGFLSFYKLVEAAASTIQNSQNFQELCEFVVKEVRNITGFDRVMLYRFDPAGHGTVLAEEKQESMNSWLNLHYPAEDIPTQARQLYSINLLRLISDVNYKPVAIVPTINPVDKRPLDLSHSVLRSVSPCHIEYLQNMKVSASMSISIVKEGKLWGLVACHHNSPKYVSYEVRKACEFFGKVMALELRSKEDNSYYEYRLQLQANTVKLVEYMSRETDFIDGLVNFQPNLLDLGQADGAVIYFKGTCCLLGQTPSRDRIERLIHWLEQQNFPTFYHTDSLPSVYPEAEIYKDIASGLLAVAISKEPKHYVLWFRSEVIHQVSWAGDPNTPFELLPGRNPRLHPRKSFEVWQEIVKLKSLPWKPCEIDAALDLKNAIVTIVLRQADELAKLNVALQESEARTKEKANQLAQTLQELKRTQTQLIEQEKMSELGELIASIVAEITNPINFITGNLSHAQEYAEDLLNLLYLYQQHYPEPVPEILETIESIDLEFTSQDFCQLIESMKGGAERIRDLVHALRNFMRLNESDLKAVDIHEGINSTLLILQHRLKGKGDSRGIQVVKAYGNLPQVECYPSQLNQVFMNLLSNAIEALESHPNHPGQKTILIRTEPLGGDRVLISIADNGVGINPTLQDQIFEPFFTTKSPKKSIGVGLAIAKEVVVEKHQGEIRCISELSQGAEFILEIPTKQPYPTSVQSVDAAG
>NC_019693.1|WP_044198014.1|6781782_6783231_+|bifunctional-orotidine-5'-phosphate-decarboxylase/orotate-phosphoribosyltransferase
MNFSDKLQTAIERNNSLLCVGLDPDPEALPSRFGTPNNPATVIAHLTDWLHFIIAQTSELVCAYKPTLGFYTALGAEGLNLLPQILQAIPRCLPVILDVKHSDLNSSTVFAQTIFERWQVDAVTLSPYPGQDLAAPFLLYPDKAVFVLCHTSNPAAQVLQHYPKNDAPLYLQVVKETRTWGTPEQVAIEVGTNTPEVLGRVRSVAPERLILARSIWSEGTVLANILQNGLNSQGDGLILPVPQDYLSSENAGSLILGLRETINQVRIRIPSEAQACPVWFPDVPATDAHPHTDLILQLYDLGCIMFGEYVQASGETFPYYVDLRTIISNPQIFDKIIGAYAEVLTTLKFDRIAGIPYGALPTATGLSLRLNYPMIFPRKEVKAHGTRRLVEGHFNPGETVVVVDDILISGKSAMEGAQKLQSTGLKVEDIVVFIDHEKGVKDRLKMNGYRAHSVLTLSEIAETLYDAGRLTDRQFQFFKDSH
>NC_019693.1|WP_156823976.1|6781633_6781774_-|hypothetical-protein
MEIESILLEFRSPPPVLPTGEITHGDRRPTRSKISNLVFTNPVNSC
>NC_019693.1|WP_015151428.1|6780935_6781511_-|hypothetical-protein
MTGEKIGKYLTLEEFCTCTQTYQTYKDQINPFPANPQETIPAILALIEAIVDPVIEEFGRDRFRLTYGFCSKDLKRYLEKKDPVTGQKNGRVAPELDQHLAHEVNPKGHYYCNRLGASCDFLILDLSSADLVEWILTHQLPFDSLYFYGENRPIHISYGPQQKRDIWTFTRGRQPTKKGIETWVELAKLIQ
>NC_019693.1|WP_015151427.1|6780220_6780763_+|Uma2-family-endonuclease
MSLTIADLEQVQLEHPEWNLELIDGGIKAMGPSDDTSSEIGAQFTFLLKLWVNPRRLGRVYDSSGGFILPNTDLRAPDVSFVLADRIKRSNRDFVRLVPDLMVEIKSKSDRLNPLADKIKLFLALGTTVGILVDPDKETVTVYRPTGETTVLNTEDTLTIPELFPGWEMPIADLWPPVFE
>NC_019693.1|WP_015151426.1|6777244_6780190_+|DNA-phosphorothioation-associated-putative-methyltransferase
MDKSSLPLPQTKLDRLASVHRHLPRPLRLAGEAGILTAETTFLDYGGDANHHPADVVYLADILNIIQSPEEREDVLQDAWKLTENVLIVAASVTVSEVNQGKIAYGKEGVIPMNSVHTYYEQVDLKRELERILSVEATPAGLGVYFIFRNPADAQNYCFNLGRSRSIIPPLHPDATALIAQEEILTPLMEFVGDWGRLPQIKELSTAKAIIREFGSLEQAFNQIQAATSEEIWQQIQEKCRQDALIYLASLIWEKQRVPSFSEFSPQIAANFRALFGNWNNAKQAAQHLLSQLESPDAVATACQNSPLGKKLPGALYVHVWAIESLDPILRLYEAVVRRHLGRVDSATLIKFNLEKPIISYLFYPEFDTDPHPALQASLRIHFPEGRIRYRDYQQVDNPPVLHRKETFVTPDYPLYELFENLTREEEKLGLLNKSRGIGTRNGWLECLADAGVEIQGHTVRVTSEPKTTNKPLKTTPKIERHRAAIVRNALSRPMRLGLEAGFFTEGTTFFDYGCGHGGDIKRIAEQGFTSSGWDPYYSPDTPLTPADVVNLGYIINVIEDLEERRQALIQSWELTQKVLIVASLVLVDDRNSGQVAYGDGVITRRHTFQKYYEQEELKQYIETVLQVEAIPVALGIYFVFRDQQLAQRIQSYRFRSRTTVPKLLKSFDEYREILTPLMEFASDRGRLPVPGELPQEPAIIAEFGNLRRAFKVIMEFTHPEEWEAITEKRRKDILTYIAVTNLLKRVQLSHLPLEIQNDIKALFPSYRTACIMAEQLVFSLNDIELVASSCKNSSVGLLKPNSFTVHVSALETLEPLLRIYEGVVSRAIGRMDEATLIKFSLKKPRISYLFYPNFDKETHPLLHTRMDIDLIDLRVIYRDYDNDDNPPILHRKDACVTPDYPDYEKLVKLTHQEENRGLLDKPWEIKTLKTWQKRLEENCAEIRGNTVFWRKDADPYRLRILKAAMRSRQRKQVETDPDLS
>NC_019693.1|WP_015151425.1|6776598_6777126_+|DUF1499-domain-containing-protein
MYNLSPVKVLTVCFSVTLAILCYLGATPAAFATEIPPNAIASLFSFSGERPDNLGVTMGKLSPCPTSPNCVSSQAEATDKKHQIEPLKYESSAKRAFAHLKEIIEEMENAKVIKSDAHYLYAEFTSSLMGYVDDVEFFLDRKSDVIQVRSASRLGQSDLGVNRKRIEEIRSKFSA
>NC_019693.1|WP_015151424.1|6776120_6776540_+|DNA-sulfur-modification-protein-DndE
MEPPLDRIKLSQTAKEQLSKLKRYTKIDQWNILCRWAFCKSLSETSTPSPVPIPADSNVEMSWRVFGGEMSDILILALKQRCHQDGLGTDKETLANQFRLHLHRGIGYLAGDPNIKKIEHLIEVAVASQTGEKESKGKR
>NC_019693.1|WP_015151423.1|6774040_6776023_+|DNA-sulfur-modification-protein-DndD
MIFIELVLQNFGPYMGRQVIDLRPQIHGETRPIILFGGMNGGGKTTLMDAIRLALYGPRAQCSTRGNLNYSDFLTQCVTRDSDPVEKTRIELVFEHFENDAAVELRIVRYWEANPKDGKDTLGILEGDWPRTDLTNIWDEYIENLLPLGISNLFLFDGEQVKELAEQETPPPVVVDAIQSLLGLELAERLSIDLDILVRRKQKKLASAKQLASLEEIEQKLSKSNEDLEEAKQELGGLQNNLEKAHERQRDAWDKFISEGGKIAAERTQLEKQKRSLEGSLEQMRESLGELAGGSLPLVLIQPLLDEVQVQGEQEAKSLQAKIARDVVKERSSRLVEYLDKLKLKPQQVDKIKFFLEQEDEALDREIGSEEDIWLSADEETLSLLANVLRHELPSQVKLAGEKLQSLEALEVEITFNERQLASAPSPEIYEQLDAALKAAQAAVVKAQGDYNNGQQRCDKLSKEIDGFKKELAVYSETSIERQNDEHIIESSKKVQETLKLFKERLTLRKLNKLEVEVTDCFRYLLHKVDLVHRIAIDKQSFGLSLYNPEGQPVPKHRLSAGEKQLLAIAFLWGLARVSGRHLPVAIDTPLGRLDSSHRNNLIERYFPSASHQVILLSTDTEISKTEYEHLVEQEAIANSYLLKYHPETRKTIVENGYFW
>NC_019693.1|WP_015151422.1|6772305_6773931_+|DNA-phosphorothioation-system-sulfurtransferase-DndC
MTEQAQMSLFPPRTVEELVEDIDNLTKEIQALYCLDEIPWIIGYSGGKDSTTILQLIWNAIADLPLSKRTKKIYVITTDTLVENPIVSAWVRKSIDRMKAAAREQKMPFEPHLLNPQVKDTFWVCLIGKGYPAPRHGFRWCTDRLKIQPVNHFIRDVVRINGETIVVLGTRKAESSKRAMTMRKHEAGRVRDRLSPNARLPNSLVYSPIEDWRNDEVWIYLNQWSNPWGQSNKDLFTMYRGATADNECPLVVDTTTPSCGDSRFGCWVCTLVNQDKSMQAMIQNDDEKEWMMPLLEIRNELDIHEDGDKRDFRRIYGKVELFERNNEGEMAVVPIPGPYLKKWREHWLRKVLSAQTKIRKNGPEDMRDITLITLAELSEIRRIWLEEKHEFDDSLPKIYEEVTGESFTDPRPGAGNQSWGSDEWEVLDEICKPDTMHLELMSKLIGTEYKYHTKSRRTGVYDALEKCFESSSRSQEEAIENAHYKRDLKTAAQEGDVYAIKQLKNRDMKATATDGDVAGIKQLSWGTMKYPSIDTDDDGEN
>NC_019693.1|WP_015151434.1|6788333_6791717_-|response-regulator
MKRPIRIDTLQWFIGIYLAIRGTLMLMLPHKLSSDIFAPFQPYVTGLGALQVMVGAALIGVATLLPLRWSILSAHLMAGVVLFQIGIGYASGGKLLGVVGALVLGLALAVAPFLSNEDERRDRQRETKIGAIDLFAVAMGSRMVLETLLFLSALNPELQASFSPVLPPYRLPYTLLYFIFGVSVLGVQLSPKVPRWFFQLVHFFAGIFLWTWIVGTGFSLWNGVLSYAGLGTALAFLPWISKRLNRLDPHSLQTRVAVASIGIVTLPLVSLTTLVSLPQEQATIERSLTVQQSLAVALSQDIATYINLHRAAIIALGNQPGLAEMEPQEQQSLLQVVHGAYPDLLVLSTFNANGQEIARSDNLPLGPSIQGMASFQEVRLTARPSLNFQVSRTVNLPVAFFLVPIQNSQGEFAGALAGSIASSRIMAQLGRMASDTSLKAYLVDTKGRVIAHPNVQLVNSFANFAQVPPVAALLESSISLGKLSYWNGTIRELVGYARVPDFGWGAIVERPADEVLETLNVRRERDFLVLLAVAAASLTIGGFLSHRLTHPLRTLAFAAQELGKGNSQAPLPNSNITELANLSLVFGTMRDRLVRRTEERDRAEAELRQSEAKFRRLVESNIIGAIVVDIEGPVIEANDEFLQMMGYTRADLASGKIHWLEIASPEYFEGVRRIRKELQETGAFAPFEMECIRADGRRVPVLLGAARLEETEDKAIAFVLDLTQRKQMEREREQLLKRERSAREDAESANRIKDEFLAVLSHELRSPLNPILGWAKLLRSRKFDQKTIDKALETIERNALLQTQLIEDLLDVSRILRGKLTLNVQPVNLISAITGAIETVSLAAEAKSIHIETRFDNAVSPVAGDVIRLQQVFWNLLSNAVKFTPANGQIEVMLAQVDSIAFIQVKDTGKGIAPQFLPYVFEYFRQEDGGTTRSFGGLGLGLAIVRYIVEQHGGSVMAESPGEGLGSTFTVNLPLMSVEPTPALGDRPPLGLMENLQGLRVLLVDDEPDLLELAAFTLEEAQAVVTSCASAAEALMALNQNRYDLLVCDIGMPDIDGYMLMRQVRSFPPELGGKIPAIALTAYASELDRQQARLAGFQLHLSKPIEPDLFIQAIAQLLQKSPGVDSQ
>NC_019693.1|WP_015151435.1|6792687_6793713_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MGTLKVGINGFGRIGRLVLRAGINNPNLEFVGINDLVPSDNLAYLFKHDSTQGKFPGSVKATAEGIEIDGKFIPCTAIKDPTELPWGKVGADYIVESTGLFTTLEGASKHIKGGAKRVVISAPTKDPDQVRTFLVGVNHETFDPAKDLVVSNASCTTNCLAPVAKVINDNFGFSEGLMTTVHAMTATQPTVDGPSKKDWRGGRGAAQNIIPAATGAAKAVTLVLPELKGKLTGMAFRVPTPDVSVVDLTFRTTKATSYKEICAAMKAASEGELKGILGYTEDEVVSTDFVGDSHSSIFDAGAGMELNSNFFKIVSWYDNEWGYSCRVVDLMLSMAKKDGIL
>NC_019693.1|WP_044198020.1|6794008_6795628_-|phosphoenolpyruvate-carboxykinase-(ATP)
MKETLTLEHDQIPKTYGLEALGMKNLGHVYRNLSIPTLVEHALARAEAVLADNGALCINTGKYTGRSPHDKFIVDEPNSRDEIHWNKLNVPISEENFKRLYRQVLSYVQGRDLYLFDGYVGCDPNYRVGVRIINQYASQNLFAHQLFIRATEEELANHQADFTVIAVPGLQGDPEINGINSEAFIVVNFSQKIVIIGGSKYSGEIKKSVFSLMNYFMTKRNVLPMHCSANMDDKGNTALFFGLSGTGKTTISADPTRRLIGDDEHGWSEEGIFNFEGGCYAKTIALSKENEPQIWDAIGFGALMENVILDPITRHPDYDDDSLTENTRVAYPIDYIPNVVLPSVGGHPTAVIFLSADAFGVLPPIAKLTNRQAMYYFMSGYTSKLAGTERGITEPEATFSACFGKPFLPLPATVYAEMLGERLRKHNSTASVYLVNTGWSGGPYGVGSRIKIKYTRAMVSAALSGELDHVTCHPHPLFKILIPEAVSGVPSEILNPRNSWTDQAAYDRQAQELARRFVDNFKRFTTASQEIIDAGPSLE
>NC_019693.1|WP_156823977.1|6796260_6796665_-|hypothetical-protein
MKRSPGVTYRLQANPVLPSGLNIFFPSTATLSFSNFFQKKTPLLSLAKNPGHAQPFCSTCLTNVMVSCYLQLELSSEKWQFFRDDSDSIADGESPLVPSGKKQRKSRPCPGNLGNNLAPNFVIFCNFFNASMRL
>NC_019693.1|WP_156824114.1|6796863_6797865_+|adenosine-deaminase-family-protein
MPKAELHLHLEAAPRWSTLREALHRHHGRELPQTPLFHAPDFRFADFDEFKGCFRHYIYPWLQTKRGYAELMEDVVDSLVEQRIRYVELNFNVATVDLLKLDLETVLEQLAASVATAGDRGTTIRIIAGIDRSQGSENARLQVQRLIPYPLISGFDLHGLETPETRADRFQDAWATAKEAGRKVKVHAGEMDGPASIYAAVATAGITQIGHGTSAIESPEVVNLLLERGVVVEMCPTSNERLGNVSSYQNHPILALDEAGVKVTVNSDDPTWFGLNLTQEMQRLIRDRQVSLDCLTRWTRNAFEVAIADDAMRSQFFTELQTWQQTHCPSLRI
>NC_019693.1|WP_015151439.1|6798242_6800531_+|formate-C-acetyltransferase
MVSTSVKSPQATELPGKQNVISEEWQGFVTGKWGKEIDVRDFIQKNYKPYQGDETFLAAPTERTTILWKQVTELMKEERLKGVLDAETKIPASITAYGPGYIDRDLERIVGLQTDKPLKRAIMPYGGIRIVKAGLEAYGYKLDPETEKIFTQYRKTHNDGVFDGYTREMRAARHSGIITGLPDAYGRGRIIGDYRRIALYGVNRLIADKKHQLESLEFDAITEPVIQLREEVSEQIRALQELKDMGAGYGFDLGQPAKTAQEAVQWTYLGYLAAVKEQNGAAMSLGRVSTFLDIYFERDLKNGTLTETDAQEIIDDFVMKLRMVRFLRTPDYNQLFSGDPTWVTECIGGMGEDGRPLVTRSSFRFLHTLYNLGAAPEPNLTILWSERLPENFKRYCAKVSIDTCSTQYENDDLMRPDYGDDYGIACCVSAMRIGKQMQFFGARANLAKALLYAINGGKDESSGEQIGPEFTPVMGDSLDYEDVVAKFDRFLDWLAKLYVNTLNVIHYMHDKYCYERIEAALHDRDIYRTLACGVAGLSVVADSLAAIKYAKVKAIRNAQGLIVDYQIEGDYPKYGNNDDRVDEIAADLVANFMNKIRKHKTYRNAVPTQSILTITSNVVYGKKTGNTPDGRKAGEPFAPGANPMHGRDTKGAIAALSSVAKLPYEHAQDGISYTFSIVPKALGKTDGDRLTNLVGILDGYFHDQGHHININVLDRETLVDAMDHPEKYPQLTIRVSGYAVNFIKLTREQQLDVINRTFHERI
>NC_019693.1|WP_015151440.1|6800630_6801413_+|pyruvate-formate-lyase-activating-protein
MLDRTANPTANPPSVRAFQALGAIHSVESCGTVDGPGIRFVIFTQGCPLRCLYCHNPDCRHIEEGKVVSVDELIEEVQKYRSYMRFSGGGVTVTGGEPLMQPEFVREIFRRCKELDIHTVLDTSGYVQLNAAKPVLDYVDLVLLDIKSYNRALYEKVTHVSLEPTLKFAEYLKEINKPAWIRFVLVPHLTDNRENVEGLAQFVSTLTNVEKVEVLPFHQMGEYKWEQLGYEYQLKNTEPPTAEQIEAVMEIFRSYGLPVQ
>NC_019693.1|WP_156823978.1|6801391_6801574_-|hypothetical-protein
MSWDTLRADRLFNSPDVSNPGTLASETDPLCQESLNIQAIAWWLSTLIFPLPTVYCTGNP
>NC_019693.1|WP_015151441.1|6801804_6804561_+|bifunctional-acetate--CoA-ligase-family-protein/GNAT-family-N-acetyltransferase
MQKPIATNADQTQGSVSTQDVLRYERQTLDAIFKPKNVALIGATDRLGSVGRTILSNLIASPFGGAVFPVNPKRDNVLGIKAYASISAVPDPVDLAIIVTPAPTVPGIIRECVDVGIPGAIIISAGFKEIGPAGIELERQILAEARRGRMQIIGPNCLGVMSPLSGLNATFATKMAKPGNVGFISQSGALCTAILDWSLRENVGFSAFMSIGSMLDVGWGDLIYYLGDDPNTQSIVIYMESIGNARSFLSAAREVALSKPIIVIKVGHTEAAAKAAASHTGTLTGSDEVLDAAFRRTGVLRVNNISYVFYMSEVLAKQPRPKGPHLTILTNAGGPGVIATDALITEGGKLTELAPETISELDEFLPTHWSRSNPIDILGDAEPSRYAKTLEKAAKDPNSDGLLVILTPQAMTDPTETAKQLEPYAKIKDKPILASWMGGEDVREGANFLNQANIPTFPYPDTAARLFNYMWRYTYNLRALYETPVLPKDDDQNTPDRALVEKIITQARKEGRNLLTEFESKQVFAAYGIPTVETHIATSEAEAVAYANQIGYPIVLKLYSETITHKTDVGGVKLNLGSPEAVENAYRAIATSVTAKAGAEYFQGVTVQPMIKLDGYELIVGSSIDPQFGPVLLFGTGGQLVEVFKDRALGLPPLNTTLARRMMEQTKIYKALQGIRGRDPVDIGAIEQLMVRFSQLIVEQPWIKETDINPLLVSPEQIIALDARVVLHEPDSNFDELPRPAIRPYPTQYITMWSMKNGTPVRIRPIRPEDEPLVVKFHESLSDRSVYFRYFHLLKLSRRISHERLARICFIDYDREMALVADYRDPATGEHQILGFGRLSKLYGSNEGEFGLLVADPYQGLGLGTKMLQQLIEVGRSEKLVRITADILPDNGAMQHLSQKVGFHLKRHEDVIRAEIEL
>NC_019693.1|WP_015151442.1|6804604_6805036_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MTLWVFDTDCLSLLQRGHPHLEQRIQQVDPEHLAVTIVTVEEQLYGRLNRIRRSPSGDALILAYAKLRETVEDFNQLNILDFDRPALTQYQELIQQRIRIGTQDLKIGAVALSRNAVLVTRNRRDFEQIPGLQWEDWTIAPEA

Crispr_ID: NC_019693_73

• CRISPR_ID: NC_019693_73
• CRISPR_location: 6795822-6795988
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_73

Consensus_repeat	Method
TTTAGGTTGGGCGCTCACCGGGCTACATTAGCAACTATTGGGTTGAAAAAGTTT	CRISPRCasFinder

spacers of NC_019693_73

>73.1|6795876|59|NC_019693|CRISPRCasFinder
TTGATTGTTCCGCGTTTGGGAAATCTACCGCTTTATTTTGAATTGTGACTGGAGTTGCG

CRISPR arrays and Neighbor proteins around NC_019693_73

CRISPR arrays

The CRISPR arrays of NC_019693_73

>merge|NC_019693|73|6795822-6795988|CRISPRCasFinder
TTTAGGTTGGGCGCTCACCGGGCTACATTAGCAACTATTGGGTTGAAAAAGTTTTTGATTGTTCCGCGTTTGGGAAATCTACCGCTTTATTTTGAATTGTGACTGGAGTTGCGTTTAGGTTGGGCGCTCACCGGGCTACATTAGCAACTATTGGGTTGGAAAAGTTT

>NC_019693|73|71|6795822-6795988|CRISPRCasFinder
TTTAGGTTGGGCGCTCACCGGGCTACATTAGCAACTATTGGGTTGAAAAAGTTT	TTGATTGTTCCGCGTTTGGGAAATCTACCGCTTTATTTTGAATTGTGACTGGAGTTGCG
TTTAGGTTGGGCGCTCACCGGGCTACATTAGCAACTATTGGGTTGGAAAAGTTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_156823977.1|6796260_6796665_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044198020.1|6794008_6795628_-|phosphoenolpyruvate-carboxykinase-(ATP)	unknown	unknown	gnl|CDD|236471
NC_019693.1|WP_015151440.1|6800630_6801413_+|pyruvate-formate-lyase-activating-protein	unknown	unknown	gnl|CDD|131546
NC_019693.1|WP_015151434.1|6788333_6791717_-|response-regulator	unknown	unknown	gnl|CDD|274362
NC_019693.1|WP_015151442.1|6804604_6805036_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350229
NC_019693.1|WP_156823976.1|6781633_6781774_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151432.1|6786468_6787752_-|cardiolipin-synthase-B	unknown	unknown	gnl|CDD|234967
NC_019693.1|WP_015151430.1|6783746_6786224_+|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|226702
NC_019693.1|WP_015151445.1|6807121_6808042_+|ornithine-carbamoyltransferase	unknown	unknown	gnl|CDD|234835
NC_019693.1|WP_015151439.1|6798242_6800531_+|formate-C-acetyltransferase	unknown	unknown	gnl|CDD|153087
NC_019693.1|WP_015151441.1|6801804_6804561_+|bifunctional-acetate--CoA-ligase-family-protein/GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|223972
NC_019693.1|WP_015151444.1|6805819_6806665_-|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl|CDD|371375
NC_019693.1|WP_156824114.1|6796863_6797865_+|adenosine-deaminase-family-protein	unknown	unknown	gnl|CDD|236480
NC_019693.1|WP_015151435.1|6792687_6793713_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|223135
NC_019693.1|WP_015151427.1|6780220_6780763_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NC_019693.1|WP_044198014.1|6781782_6783231_+|bifunctional-orotidine-5'-phosphate-decarboxylase/orotate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|180119
NC_019693.1|WP_015151428.1|6780935_6781511_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151443.1|6805032_6805437_-|hypothetical-protein	unknown	unknown	gnl|CDD|239432
NC_019693.1|WP_015151426.1|6777244_6780190_+|DNA-phosphorothioation-associated-putative-methyltransferase	unknown	unknown	gnl|CDD|274979
NC_019693.1|WP_156823978.1|6801391_6801574_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_044198020.1|6794008_6795628_-|phosphoenolpyruvate-carboxykinase-(ATP)	gnl|CDD|236471	PRK09344, PRK09344, phosphoenolpyruvate carboxykinase.	0
NC_019693.1|WP_015151440.1|6800630_6801413_+|pyruvate-formate-lyase-activating-protein	gnl|CDD|131546	TIGR02493, PFLA, pyruvate formate-lyase 1-activating enzyme. An iron-sulfur protein with a radical-SAM domain (pfam04055). A single glycine residue in EC 2.3.1.54, formate C-acetyltransferase (formate-pyruvate lyase), is oxidized to the corresponding radical by transfer of H from its CH2 to AdoMet with concomitant cleavage of the latter. The reaction requires Fe2+. The first stage is reduction of the AdoMet to give methionine and the 5'-deoxyadenosin-5-yl radical, which then abstracts a hydrogen radical from the glycine residue. [Energy metabolism, Anaerobic, Protein fate, Protein modification and repair].	1.09954e-124
NC_019693.1|WP_015151434.1|6788333_6791717_-|response-regulator	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	4.03539e-55
NC_019693.1|WP_015151442.1|6804604_6805036_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350229	cd09881, PIN_VapC4-5_FitB-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4 and VapC5, and Neisseria gonorrhoeae FitB and related proteins. This family includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This family belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.06377e-28
NC_019693.1|WP_015151432.1|6786468_6787752_-|cardiolipin-synthase-B	gnl|CDD|234967	PRK01642, cls, cardiolipin synthetase; Reviewed.	4.49298e-71
NC_019693.1|WP_015151430.1|6783746_6786224_+|GAF-domain-containing-protein	gnl|CDD|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	0
NC_019693.1|WP_015151439.1|6798242_6800531_+|formate-C-acetyltransferase	gnl|CDD|153087	cd01678, PFL1, Pyruvate formate lyase 1. Pyruvate formate lyase catalyzes a key step in anaerobic glycolysis, the conversion of pyruvate and CoenzymeA to formate and acetylCoA. The PFL mechanism involves an unusual radical cleavage of pyruvate in which two cysteines and one glycine form radicals that are required for catalysis. PFL has a ten-stranded alpha/beta barrel domain that is structurally similar to those of all three ribonucleotide reductase (RNR) classes as well as benzylsuccinate synthase and B12-independent glycerol dehydratase.	0
NC_019693.1|WP_015151441.1|6801804_6804561_+|bifunctional-acetate--CoA-ligase-family-protein/GNAT-family-N-acetyltransferase	gnl|CDD|223972	COG1042, COG1042, Acyl-CoA synthetase (NDP forming) [Energy production and conversion].	0
NC_019693.1|WP_015151444.1|6805819_6806665_-|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl|CDD|371375	pfam11103, DUF2887, Protein of unknown function (DUF2887). This bacterial family of proteins has no known function. These proteins may be distantly related to the PD(D/E)XK superfamily.	3.02255e-97
NC_019693.1|WP_015151426.1|6777244_6780190_+|DNA-phosphorothioation-associated-putative-methyltransferase	gnl|CDD|274979	TIGR04096, conserved_hypothetical_protein, DNA phosphorothioation-associated putative methyltransferase. Members of this protein family show distant local sequence similarity to a number of S-adenosyl-methionine-dependent methyltransferases. The family is identified by Partial Phylogenetic Profiling as closely tied to the DNA phosphorothioation system (dnd), and members are found adjacent to dnd genes in at least 13 species (Streptomyces lividans TK24, Shewanella frigidimarina NCIMB 400, Mycobacterium abscessus ATCC 19977, Nostoc punctiforme PCC 73102, Vibrio fischeri MJ11, etc.). The DNA phosphorothioation enables a novel form of restriction enzyme activity. Most members of this family appear in species with the DNA phosphorothioation system. [DNA metabolism, Restriction/modification].	0
NC_019693.1|WP_015151435.1|6792687_6793713_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl|CDD|223135	COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism].	0
NC_019693.1|WP_015151427.1|6780220_6780763_+|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	1.02472e-34
NC_019693.1|WP_044198014.1|6781782_6783231_+|bifunctional-orotidine-5'-phosphate-decarboxylase/orotate-phosphoribosyltransferase	gnl|CDD|180119	PRK05500, PRK05500, bifunctional orotidine-5'-phosphate decarboxylase/orotate phosphoribosyltransferase.	0
NC_019693.1|WP_015151443.1|6805032_6805437_-|hypothetical-protein	gnl|CDD|239432	cd03316, MR_like, Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues, a Lys-X-Lys motif and a conserved histidine-aspartate dyad. Members of the MR subgroup are mandelate racemase, D-glucarate/L-idarate dehydratase (GlucD), D-altronate/D-mannonate dehydratase , D-galactonate dehydratase (GalD) , D-gluconate dehydratase (GlcD), and L-rhamnonate dehydratase (RhamD).	0.00434406
NC_019693.1|WP_156824114.1|6796863_6797865_+|adenosine-deaminase-family-protein	gnl|CDD|236480	PRK09358, PRK09358, adenosine deaminase; Provisional.	7.17265e-73
NC_019693.1|WP_015151445.1|6807121_6808042_+|ornithine-carbamoyltransferase	gnl|CDD|234835	PRK00779, PRK00779, ornithine carbamoyltransferase; Provisional.	0

Protein sequences

>NC_019693.1|WP_044198020.1|6794008_6795628_-|phosphoenolpyruvate-carboxykinase-(ATP)
MKETLTLEHDQIPKTYGLEALGMKNLGHVYRNLSIPTLVEHALARAEAVLADNGALCINTGKYTGRSPHDKFIVDEPNSRDEIHWNKLNVPISEENFKRLYRQVLSYVQGRDLYLFDGYVGCDPNYRVGVRIINQYASQNLFAHQLFIRATEEELANHQADFTVIAVPGLQGDPEINGINSEAFIVVNFSQKIVIIGGSKYSGEIKKSVFSLMNYFMTKRNVLPMHCSANMDDKGNTALFFGLSGTGKTTISADPTRRLIGDDEHGWSEEGIFNFEGGCYAKTIALSKENEPQIWDAIGFGALMENVILDPITRHPDYDDDSLTENTRVAYPIDYIPNVVLPSVGGHPTAVIFLSADAFGVLPPIAKLTNRQAMYYFMSGYTSKLAGTERGITEPEATFSACFGKPFLPLPATVYAEMLGERLRKHNSTASVYLVNTGWSGGPYGVGSRIKIKYTRAMVSAALSGELDHVTCHPHPLFKILIPEAVSGVPSEILNPRNSWTDQAAYDRQAQELARRFVDNFKRFTTASQEIIDAGPSLE
>NC_019693.1|WP_015151435.1|6792687_6793713_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MGTLKVGINGFGRIGRLVLRAGINNPNLEFVGINDLVPSDNLAYLFKHDSTQGKFPGSVKATAEGIEIDGKFIPCTAIKDPTELPWGKVGADYIVESTGLFTTLEGASKHIKGGAKRVVISAPTKDPDQVRTFLVGVNHETFDPAKDLVVSNASCTTNCLAPVAKVINDNFGFSEGLMTTVHAMTATQPTVDGPSKKDWRGGRGAAQNIIPAATGAAKAVTLVLPELKGKLTGMAFRVPTPDVSVVDLTFRTTKATSYKEICAAMKAASEGELKGILGYTEDEVVSTDFVGDSHSSIFDAGAGMELNSNFFKIVSWYDNEWGYSCRVVDLMLSMAKKDGIL
>NC_019693.1|WP_015151434.1|6788333_6791717_-|response-regulator
MKRPIRIDTLQWFIGIYLAIRGTLMLMLPHKLSSDIFAPFQPYVTGLGALQVMVGAALIGVATLLPLRWSILSAHLMAGVVLFQIGIGYASGGKLLGVVGALVLGLALAVAPFLSNEDERRDRQRETKIGAIDLFAVAMGSRMVLETLLFLSALNPELQASFSPVLPPYRLPYTLLYFIFGVSVLGVQLSPKVPRWFFQLVHFFAGIFLWTWIVGTGFSLWNGVLSYAGLGTALAFLPWISKRLNRLDPHSLQTRVAVASIGIVTLPLVSLTTLVSLPQEQATIERSLTVQQSLAVALSQDIATYINLHRAAIIALGNQPGLAEMEPQEQQSLLQVVHGAYPDLLVLSTFNANGQEIARSDNLPLGPSIQGMASFQEVRLTARPSLNFQVSRTVNLPVAFFLVPIQNSQGEFAGALAGSIASSRIMAQLGRMASDTSLKAYLVDTKGRVIAHPNVQLVNSFANFAQVPPVAALLESSISLGKLSYWNGTIRELVGYARVPDFGWGAIVERPADEVLETLNVRRERDFLVLLAVAAASLTIGGFLSHRLTHPLRTLAFAAQELGKGNSQAPLPNSNITELANLSLVFGTMRDRLVRRTEERDRAEAELRQSEAKFRRLVESNIIGAIVVDIEGPVIEANDEFLQMMGYTRADLASGKIHWLEIASPEYFEGVRRIRKELQETGAFAPFEMECIRADGRRVPVLLGAARLEETEDKAIAFVLDLTQRKQMEREREQLLKRERSAREDAESANRIKDEFLAVLSHELRSPLNPILGWAKLLRSRKFDQKTIDKALETIERNALLQTQLIEDLLDVSRILRGKLTLNVQPVNLISAITGAIETVSLAAEAKSIHIETRFDNAVSPVAGDVIRLQQVFWNLLSNAVKFTPANGQIEVMLAQVDSIAFIQVKDTGKGIAPQFLPYVFEYFRQEDGGTTRSFGGLGLGLAIVRYIVEQHGGSVMAESPGEGLGSTFTVNLPLMSVEPTPALGDRPPLGLMENLQGLRVLLVDDEPDLLELAAFTLEEAQAVVTSCASAAEALMALNQNRYDLLVCDIGMPDIDGYMLMRQVRSFPPELGGKIPAIALTAYASELDRQQARLAGFQLHLSKPIEPDLFIQAIAQLLQKSPGVDSQ
>NC_019693.1|WP_015151432.1|6786468_6787752_-|cardiolipin-synthase-B
MNSVLVWILLIIIGLAILLLIALYIRGTFRDRVEYKVKNPPAPGEPRFTIAQASLSNSLITSALVTDVWNDSPTIQQVRLDAIANAKSSIHFETFFITPGRRANDFAAAIAERAAAGVAVKLLVDSYGSKKIPDKYWNRLKAAGVKVLFFNPFDWKAPADYAGRTHRKLLSIDSKVAYIGGAGISDFWDGESGSGEKEPWFDCEFRLEGEIVAVLEGVFVQHWTYASGVANLGPEIFKKDPAQKPVTLVTPSFNPTYRFSPIRALFQTSLLAARKRIWLASPYFFPDLNSRDLLIAAKKSGLDVKILTTSSVSDKKKVYYASYEGYGPLLAAGIEIHEYQPSMTHAKLLLIDDHWMTTGSANFDPRSFFHNDELDFSTGEPNVLREVEQIFQRGFSKSKVASLEDWRKRSLWKRMVGQTVRFFEWQL
>NC_019693.1|WP_015151430.1|6783746_6786224_+|GAF-domain-containing-protein
MMQPETVSWANYEREPIQSPGLIQPHGVLFVLSPDLKILQVSNNTVKFFGRPPERFLGKPLQTLLDAAQINVIHESINYQTLGSVNPLNITIHTDWETLYFDGIIHHSHSDCFILELEPALSPKTVGFLSFYKLVEAAASTIQNSQNFQELCEFVVKEVRNITGFDRVMLYRFDPAGHGTVLAEEKQESMNSWLNLHYPAEDIPTQARQLYSINLLRLISDVNYKPVAIVPTINPVDKRPLDLSHSVLRSVSPCHIEYLQNMKVSASMSISIVKEGKLWGLVACHHNSPKYVSYEVRKACEFFGKVMALELRSKEDNSYYEYRLQLQANTVKLVEYMSRETDFIDGLVNFQPNLLDLGQADGAVIYFKGTCCLLGQTPSRDRIERLIHWLEQQNFPTFYHTDSLPSVYPEAEIYKDIASGLLAVAISKEPKHYVLWFRSEVIHQVSWAGDPNTPFELLPGRNPRLHPRKSFEVWQEIVKLKSLPWKPCEIDAALDLKNAIVTIVLRQADELAKLNVALQESEARTKEKANQLAQTLQELKRTQTQLIEQEKMSELGELIASIVAEITNPINFITGNLSHAQEYAEDLLNLLYLYQQHYPEPVPEILETIESIDLEFTSQDFCQLIESMKGGAERIRDLVHALRNFMRLNESDLKAVDIHEGINSTLLILQHRLKGKGDSRGIQVVKAYGNLPQVECYPSQLNQVFMNLLSNAIEALESHPNHPGQKTILIRTEPLGGDRVLISIADNGVGINPTLQDQIFEPFFTTKSPKKSIGVGLAIAKEVVVEKHQGEIRCISELSQGAEFILEIPTKQPYPTSVQSVDAAG
>NC_019693.1|WP_044198014.1|6781782_6783231_+|bifunctional-orotidine-5'-phosphate-decarboxylase/orotate-phosphoribosyltransferase
MNFSDKLQTAIERNNSLLCVGLDPDPEALPSRFGTPNNPATVIAHLTDWLHFIIAQTSELVCAYKPTLGFYTALGAEGLNLLPQILQAIPRCLPVILDVKHSDLNSSTVFAQTIFERWQVDAVTLSPYPGQDLAAPFLLYPDKAVFVLCHTSNPAAQVLQHYPKNDAPLYLQVVKETRTWGTPEQVAIEVGTNTPEVLGRVRSVAPERLILARSIWSEGTVLANILQNGLNSQGDGLILPVPQDYLSSENAGSLILGLRETINQVRIRIPSEAQACPVWFPDVPATDAHPHTDLILQLYDLGCIMFGEYVQASGETFPYYVDLRTIISNPQIFDKIIGAYAEVLTTLKFDRIAGIPYGALPTATGLSLRLNYPMIFPRKEVKAHGTRRLVEGHFNPGETVVVVDDILISGKSAMEGAQKLQSTGLKVEDIVVFIDHEKGVKDRLKMNGYRAHSVLTLSEIAETLYDAGRLTDRQFQFFKDSH
>NC_019693.1|WP_156823976.1|6781633_6781774_-|hypothetical-protein
MEIESILLEFRSPPPVLPTGEITHGDRRPTRSKISNLVFTNPVNSC
>NC_019693.1|WP_015151428.1|6780935_6781511_-|hypothetical-protein
MTGEKIGKYLTLEEFCTCTQTYQTYKDQINPFPANPQETIPAILALIEAIVDPVIEEFGRDRFRLTYGFCSKDLKRYLEKKDPVTGQKNGRVAPELDQHLAHEVNPKGHYYCNRLGASCDFLILDLSSADLVEWILTHQLPFDSLYFYGENRPIHISYGPQQKRDIWTFTRGRQPTKKGIETWVELAKLIQ
>NC_019693.1|WP_015151427.1|6780220_6780763_+|Uma2-family-endonuclease
MSLTIADLEQVQLEHPEWNLELIDGGIKAMGPSDDTSSEIGAQFTFLLKLWVNPRRLGRVYDSSGGFILPNTDLRAPDVSFVLADRIKRSNRDFVRLVPDLMVEIKSKSDRLNPLADKIKLFLALGTTVGILVDPDKETVTVYRPTGETTVLNTEDTLTIPELFPGWEMPIADLWPPVFE
>NC_019693.1|WP_015151426.1|6777244_6780190_+|DNA-phosphorothioation-associated-putative-methyltransferase
MDKSSLPLPQTKLDRLASVHRHLPRPLRLAGEAGILTAETTFLDYGGDANHHPADVVYLADILNIIQSPEEREDVLQDAWKLTENVLIVAASVTVSEVNQGKIAYGKEGVIPMNSVHTYYEQVDLKRELERILSVEATPAGLGVYFIFRNPADAQNYCFNLGRSRSIIPPLHPDATALIAQEEILTPLMEFVGDWGRLPQIKELSTAKAIIREFGSLEQAFNQIQAATSEEIWQQIQEKCRQDALIYLASLIWEKQRVPSFSEFSPQIAANFRALFGNWNNAKQAAQHLLSQLESPDAVATACQNSPLGKKLPGALYVHVWAIESLDPILRLYEAVVRRHLGRVDSATLIKFNLEKPIISYLFYPEFDTDPHPALQASLRIHFPEGRIRYRDYQQVDNPPVLHRKETFVTPDYPLYELFENLTREEEKLGLLNKSRGIGTRNGWLECLADAGVEIQGHTVRVTSEPKTTNKPLKTTPKIERHRAAIVRNALSRPMRLGLEAGFFTEGTTFFDYGCGHGGDIKRIAEQGFTSSGWDPYYSPDTPLTPADVVNLGYIINVIEDLEERRQALIQSWELTQKVLIVASLVLVDDRNSGQVAYGDGVITRRHTFQKYYEQEELKQYIETVLQVEAIPVALGIYFVFRDQQLAQRIQSYRFRSRTTVPKLLKSFDEYREILTPLMEFASDRGRLPVPGELPQEPAIIAEFGNLRRAFKVIMEFTHPEEWEAITEKRRKDILTYIAVTNLLKRVQLSHLPLEIQNDIKALFPSYRTACIMAEQLVFSLNDIELVASSCKNSSVGLLKPNSFTVHVSALETLEPLLRIYEGVVSRAIGRMDEATLIKFSLKKPRISYLFYPNFDKETHPLLHTRMDIDLIDLRVIYRDYDNDDNPPILHRKDACVTPDYPDYEKLVKLTHQEENRGLLDKPWEIKTLKTWQKRLEENCAEIRGNTVFWRKDADPYRLRILKAAMRSRQRKQVETDPDLS
>NC_019693.1|WP_156823977.1|6796260_6796665_-|hypothetical-protein
MKRSPGVTYRLQANPVLPSGLNIFFPSTATLSFSNFFQKKTPLLSLAKNPGHAQPFCSTCLTNVMVSCYLQLELSSEKWQFFRDDSDSIADGESPLVPSGKKQRKSRPCPGNLGNNLAPNFVIFCNFFNASMRL
>NC_019693.1|WP_156824114.1|6796863_6797865_+|adenosine-deaminase-family-protein
MPKAELHLHLEAAPRWSTLREALHRHHGRELPQTPLFHAPDFRFADFDEFKGCFRHYIYPWLQTKRGYAELMEDVVDSLVEQRIRYVELNFNVATVDLLKLDLETVLEQLAASVATAGDRGTTIRIIAGIDRSQGSENARLQVQRLIPYPLISGFDLHGLETPETRADRFQDAWATAKEAGRKVKVHAGEMDGPASIYAAVATAGITQIGHGTSAIESPEVVNLLLERGVVVEMCPTSNERLGNVSSYQNHPILALDEAGVKVTVNSDDPTWFGLNLTQEMQRLIRDRQVSLDCLTRWTRNAFEVAIADDAMRSQFFTELQTWQQTHCPSLRI
>NC_019693.1|WP_015151439.1|6798242_6800531_+|formate-C-acetyltransferase
MVSTSVKSPQATELPGKQNVISEEWQGFVTGKWGKEIDVRDFIQKNYKPYQGDETFLAAPTERTTILWKQVTELMKEERLKGVLDAETKIPASITAYGPGYIDRDLERIVGLQTDKPLKRAIMPYGGIRIVKAGLEAYGYKLDPETEKIFTQYRKTHNDGVFDGYTREMRAARHSGIITGLPDAYGRGRIIGDYRRIALYGVNRLIADKKHQLESLEFDAITEPVIQLREEVSEQIRALQELKDMGAGYGFDLGQPAKTAQEAVQWTYLGYLAAVKEQNGAAMSLGRVSTFLDIYFERDLKNGTLTETDAQEIIDDFVMKLRMVRFLRTPDYNQLFSGDPTWVTECIGGMGEDGRPLVTRSSFRFLHTLYNLGAAPEPNLTILWSERLPENFKRYCAKVSIDTCSTQYENDDLMRPDYGDDYGIACCVSAMRIGKQMQFFGARANLAKALLYAINGGKDESSGEQIGPEFTPVMGDSLDYEDVVAKFDRFLDWLAKLYVNTLNVIHYMHDKYCYERIEAALHDRDIYRTLACGVAGLSVVADSLAAIKYAKVKAIRNAQGLIVDYQIEGDYPKYGNNDDRVDEIAADLVANFMNKIRKHKTYRNAVPTQSILTITSNVVYGKKTGNTPDGRKAGEPFAPGANPMHGRDTKGAIAALSSVAKLPYEHAQDGISYTFSIVPKALGKTDGDRLTNLVGILDGYFHDQGHHININVLDRETLVDAMDHPEKYPQLTIRVSGYAVNFIKLTREQQLDVINRTFHERI
>NC_019693.1|WP_015151440.1|6800630_6801413_+|pyruvate-formate-lyase-activating-protein
MLDRTANPTANPPSVRAFQALGAIHSVESCGTVDGPGIRFVIFTQGCPLRCLYCHNPDCRHIEEGKVVSVDELIEEVQKYRSYMRFSGGGVTVTGGEPLMQPEFVREIFRRCKELDIHTVLDTSGYVQLNAAKPVLDYVDLVLLDIKSYNRALYEKVTHVSLEPTLKFAEYLKEINKPAWIRFVLVPHLTDNRENVEGLAQFVSTLTNVEKVEVLPFHQMGEYKWEQLGYEYQLKNTEPPTAEQIEAVMEIFRSYGLPVQ
>NC_019693.1|WP_156823978.1|6801391_6801574_-|hypothetical-protein
MSWDTLRADRLFNSPDVSNPGTLASETDPLCQESLNIQAIAWWLSTLIFPLPTVYCTGNP
>NC_019693.1|WP_015151441.1|6801804_6804561_+|bifunctional-acetate--CoA-ligase-family-protein/GNAT-family-N-acetyltransferase
MQKPIATNADQTQGSVSTQDVLRYERQTLDAIFKPKNVALIGATDRLGSVGRTILSNLIASPFGGAVFPVNPKRDNVLGIKAYASISAVPDPVDLAIIVTPAPTVPGIIRECVDVGIPGAIIISAGFKEIGPAGIELERQILAEARRGRMQIIGPNCLGVMSPLSGLNATFATKMAKPGNVGFISQSGALCTAILDWSLRENVGFSAFMSIGSMLDVGWGDLIYYLGDDPNTQSIVIYMESIGNARSFLSAAREVALSKPIIVIKVGHTEAAAKAAASHTGTLTGSDEVLDAAFRRTGVLRVNNISYVFYMSEVLAKQPRPKGPHLTILTNAGGPGVIATDALITEGGKLTELAPETISELDEFLPTHWSRSNPIDILGDAEPSRYAKTLEKAAKDPNSDGLLVILTPQAMTDPTETAKQLEPYAKIKDKPILASWMGGEDVREGANFLNQANIPTFPYPDTAARLFNYMWRYTYNLRALYETPVLPKDDDQNTPDRALVEKIITQARKEGRNLLTEFESKQVFAAYGIPTVETHIATSEAEAVAYANQIGYPIVLKLYSETITHKTDVGGVKLNLGSPEAVENAYRAIATSVTAKAGAEYFQGVTVQPMIKLDGYELIVGSSIDPQFGPVLLFGTGGQLVEVFKDRALGLPPLNTTLARRMMEQTKIYKALQGIRGRDPVDIGAIEQLMVRFSQLIVEQPWIKETDINPLLVSPEQIIALDARVVLHEPDSNFDELPRPAIRPYPTQYITMWSMKNGTPVRIRPIRPEDEPLVVKFHESLSDRSVYFRYFHLLKLSRRISHERLARICFIDYDREMALVADYRDPATGEHQILGFGRLSKLYGSNEGEFGLLVADPYQGLGLGTKMLQQLIEVGRSEKLVRITADILPDNGAMQHLSQKVGFHLKRHEDVIRAEIEL
>NC_019693.1|WP_015151442.1|6804604_6805036_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MTLWVFDTDCLSLLQRGHPHLEQRIQQVDPEHLAVTIVTVEEQLYGRLNRIRRSPSGDALILAYAKLRETVEDFNQLNILDFDRPALTQYQELIQQRIRIGTQDLKIGAVALSRNAVLVTRNRRDFEQIPGLQWEDWTIAPEA
>NC_019693.1|WP_015151443.1|6805032_6805437_-|hypothetical-protein
MTTDLLNIQVQKPAETSWNKINLTVLIAEKAEGGYQATVLGWSDCQGSGLTKEEAIANLNQALSTRLETTEIASLQIVNPNAEHPWMKLAGKYKDDPDFDEMLADIEALRQERDAEIEIMVEYNPQLDAEELGK
>NC_019693.1|WP_015151444.1|6805819_6806665_-|Rpn-family-recombination-promoting-nuclease/putative-transposase
MRTDTIFYQLFQTFPSLVFELMGEAGEKAQGYEFTSREVKELARRFDGVLLPPEGDNERLIYFLEVQFQNKEDFYWRFFGEIFVYLGQYQPMQDFQAVAIFASRSCDPGVPRQYQRFLRSDSPEETPLLVQLYLDELEDPPTPSLGLGMVNLVVEERQRAIDKAHQLINQAKQQLVDEALKQKVVGLIETIMVYKLTDLTTQEIEAMFGLDELKQTRYFQEVAAKAKLEGQIEGKLKAVPVLFAQGLTVQQIVLALELDVEQVRQVIQDLSNPDNPPQSQS
>NC_019693.1|WP_015151445.1|6807121_6808042_+|ornithine-carbamoyltransferase
MATLTGRDLLSVADLSVEELHQLLDLATQMKAGTLTPRCEKVLGLLFSKASTRTRVSFTVAMYQLGGQVIDLNPNVTQVSRGEPLPDTARVLDRYLDVVAIRTFDQADLETFANYAEMPVINALSDREHPCQALADIMTVGECFGQLEDVTLTYLGDGNNVAHSLLLAGAMVGMNIRIATPAQFEPDPAIVEQAKKIAQGKSEVLITDDPIQAVKGAQVLYTDVWASMGQEEEARTRIPLFQPYQVNEDLFNHADGSAIILHCLPAHRGEEITDGAIEGAASRVWDQAENRMHAQKALLASVLGAI

Crispr_ID: NC_019693_74

• CRISPR_ID: NC_019693_74
• CRISPR_location: 6820551-6820660
• CRISPR_type: TypeV-U4
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: c2c9_V-U4

Consensus repeat of NC_019693_74

Consensus_repeat	Method
ATGATTTTTGCCGGTTGACACAACTTTA	CRISPRCasFinder

spacers of NC_019693_74

>74.1|6820579|54|NC_019693|CRISPRCasFinder
GGAAAGAAACCCGGTTTCTGACCCCAAAGTTAAGCGAGAAACCGGGTTTCTGCC

CRISPR arrays and Neighbor proteins around NC_019693_74

CRISPR arrays

The CRISPR arrays of NC_019693_74

>merge|NC_019693|74|6820551-6820660|CRISPRCasFinder
ATGATTTTTGCCGGTTGACACAACTTTAGGAAAGAAACCCGGTTTCTGACCCCAAAGTTAAGCGAGAAACCGGGTTTCTGCCATGATTTTTGCCGGTTGACACAACTTTA

>NC_019693|74|72|6820551-6820660|CRISPRCasFinder
ATGATTTTTGCCGGTTGACACAACTTTA	GGAAAGAAACCCGGTTTCTGACCCCAAAGTTAAGCGAGAAACCGGGTTTCTGCC
ATGATTTTTGCCGGTTGACACAACTTTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015151464.1|6831578_6832430_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293801
NC_019693.1|WP_015151462.1|6830107_6830632_+|inorganic-diphosphatase	unknown	unknown	gnl|CDD|238239
NC_019693.1|WP_044198024.1|6810165_6810417_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151465.1|6832800_6834078_+|transposase	c2c9_V-U4	-	gnl|CDD|223747
NC_019693.1|WP_156823979.1|6814503_6814647_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151460.1|6827421_6829233_-|DNA-repair-protein-RecN	unknown	unknown	gnl|CDD|223571
NC_019693.1|WP_015151463.1|6831111_6831501_+|aspartate-1-decarboxylase	unknown	unknown	gnl|CDD|376751
NC_019693.1|WP_015151456.1|6818902_6820471_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|378963
NC_019693.1|WP_015151459.1|6824054_6826727_-|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|143636
NC_019693.1|WP_015151451.1|6813438_6814074_+|threonylcarbamoyl-AMP-synthase	unknown	unknown	gnl|CDD|272879
NC_019693.1|WP_015151455.1|6817966_6818650_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|381154
NC_019693.1|WP_044196019.1|6820711_6822820_-|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl|CDD|223733
NC_019693.1|WP_015151450.1|6811963_6813280_-|nickel-pincer-cofactor-biosynthesis-protein-LarC	unknown	unknown	gnl|CDD|235249
NC_019693.1|WP_015151453.1|6816879_6817623_+|PHP-domain-containing-protein	unknown	unknown	gnl|CDD|213993
NC_019693.1|WP_015151461.1|6829468_6829660_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151458.1|6823090_6823933_-|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl|CDD|143636
NC_019693.1|WP_044198026.1|6810444_6810900_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_019693.1|WP_015151449.1|6811140_6811905_-|adenine-specific-DNA-methyltransferase	unknown	unknown	gnl|CDD|183177
NC_019693.1|WP_156824115.1|6814880_6816086_+|HetZ-related-protein	unknown	unknown	unknown
NC_019693.1|WP_015151466.1|6834128_6834926_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_015151465.1|6832800_6834078_+|transposase	c2c9_V-U4	-	3.1e-69	228.7	0.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015151464.1|6831578_6832430_+|MBL-fold-metallo-hydrolase	gnl|CDD|293801	cd07715, TaR3-like_MBL-fold, MBL-fold metallo-hydrolase domain of Myxococcus xanthus TaR3 and related proteins; MBL-fold metallo-hydrolase domain. Myxococcus xanthus Tar3 may function as an ammonium regulator/effector protein involved in biosynthesis of the antibiotic TA. Some are members of this subgroup are annotated as ribonucleases. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	7.07189e-113
NC_019693.1|WP_015151462.1|6830107_6830632_+|inorganic-diphosphatase	gnl|CDD|238239	cd00412, pyrophosphatase, Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers.	7.99343e-79
NC_019693.1|WP_015151466.1|6834128_6834926_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.39495e-34
NC_019693.1|WP_015151465.1|6832800_6834078_+|transposase	gnl|CDD|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.86686e-32
NC_019693.1|WP_015151458.1|6823090_6823933_-|adenylate/guanylate-cyclase-domain-containing-protein	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	1.29087e-36
NC_019693.1|WP_015151460.1|6827421_6829233_-|DNA-repair-protein-RecN	gnl|CDD|223571	COG0497, RecN, ATPase involved in DNA repair [DNA replication, recombination, and repair].	0
NC_019693.1|WP_015151463.1|6831111_6831501_+|aspartate-1-decarboxylase	gnl|CDD|376751	pfam02261, Asp_decarbox, Aspartate decarboxylase. Decarboxylation of aspartate is the major route of beta-alanine production in bacteria, and is catalyzed by the enzyme aspartate decarboxylase EC:4.1.1.11 which requires a pyruvoyl group for its activity. It is synthesized initially as a proenzyme which is then proteolytically cleaved to an alpha (C-terminal) and beta (N-terminal) subunit and a pyruvoyl group. This family contains both chains of aspartate decarboxylase.	1.8682e-71
NC_019693.1|WP_015151456.1|6818902_6820471_+|FAD-dependent-oxidoreductase	gnl|CDD|378963	pfam12831, FAD_oxidored, FAD dependent oxidoreductase. This family of proteins contains FAD dependent oxidoreductases and related proteins.	1.7903e-10
NC_019693.1|WP_015151459.1|6824054_6826727_-|GAF-domain-containing-protein	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	2.69287e-65
NC_019693.1|WP_015151451.1|6813438_6814074_+|threonylcarbamoyl-AMP-synthase	gnl|CDD|272879	TIGR00057, Putative_threonylcarbamoyl-AMP_synthase, tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family. Has paralogs, but YrdC called a tRNA modification protein. Ref 2 authors say probably heteromultimeric complex. Paralogs may mean its does the final binding to the tRNA. [Protein synthesis, tRNA and rRNA base modification].	4.46717e-77
NC_019693.1|WP_015151455.1|6817966_6818650_-|response-regulator-transcription-factor	gnl|CDD|381154	cd19927, REC_Ycf29, phosphoacceptor receiver (REC) domain of probable transcriptional regulator Ycf29. Ycf29 is a probable response regulator of a two-component system (TCS), typically consisting a sensor and a response regulator, that functions in adaptation to changing environments. Processes regulated by TCSs in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Ycf29 contains an N-terminal REC domain and a LuxR-type helix-turn-helix DNA-binding output domain. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays.	3.6317e-55
NC_019693.1|WP_044196019.1|6820711_6822820_-|AarF/ABC1/UbiB-kinase-family-protein	gnl|CDD|223733	COG0661, AarF, Predicted unusual protein kinase [General function prediction only].	1.53723e-178
NC_019693.1|WP_015151450.1|6811963_6813280_-|nickel-pincer-cofactor-biosynthesis-protein-LarC	gnl|CDD|235249	PRK04194, PRK04194, nickel pincer cofactor biosynthesis protein LarC.	0
NC_019693.1|WP_015151453.1|6816879_6817623_+|PHP-domain-containing-protein	gnl|CDD|213993	cd07438, PHP_HisPPase_AMP, Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound. The PHP domain of this HisPPase family has an unknown function. It has a second domain inserted in the middle that binds adenosine 5-monophosphate (AMP). The PHP (also called histidinol phosphatase-2/HIS2) domain is associated with several types of DNA polymerases, such as PolIIIA and family X DNA polymerases, stand alone histidinol phosphate phosphatases (HisPPases), and a number of uncharacterized protein families. HisPPase catalyzes the eighth step of histidine biosynthesis, in which L-histidinol phosphate undergoes dephosphorylation to give histidinol. The PHP domain has four conserved sequence motifs and contains an invariant histidine that is involved in metal ion coordination. The PHP domain of HisPPase is structurally homologous to the other members of the PHP family that have a distorted (beta/alpha)7 barrel fold with a trinuclear metal site on the C-terminal side of the barrel.	7.87015e-49
NC_019693.1|WP_044198026.1|6810444_6810900_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	9.10598e-21
NC_019693.1|WP_015151449.1|6811140_6811905_-|adenine-specific-DNA-methyltransferase	gnl|CDD|183177	PRK11524, PRK11524, adenine-specific DNA-methyltransferase.	5.8607e-146

Protein sequences

>NC_019693.1|WP_015151456.1|6818902_6820471_+|FAD-dependent-oxidoreductase
MNLNTKERYYDIIGFGDEVPGVLAMVAAAREYRRQTKKYPKMLLMSKANAGEGIGGHLIRGKLSYLDRTQINRQLQTSLNLDTFGAPSALYQEFLKRAGVVQIALDPEKGDRALREMLREAGVAILSEVKIASVVKSGSNLTSILTSRGETYTAKQFIDSTVNAELAQAAGAKKSQGFGTFGLPDSELPVTLVFETEGLSIQRLKEIELIYLKRFRNLADTEAQNFLKSAAGFDERKAESLRQELVDSHGNLKTLWAGKDYIDIRCNALSIAYHSFRGKKLSLYDSGAILDRGNVAILSGDRLSWNALMIAVTGSEAETLANNGGKPTPAMLEEMKFVQQWFKSIGAKKVTPASELYIRHAGNITEAIEPLSGAEMLAGGVAKSEALATFAYHFDVRGGIPGIGDKALANGFVSTMFSKPIFNVGIRHAQLKSVRNLAVVSPASGFEGFASAAGRIVEYNAAVGHGLGIAATLALLSNRTLADISNQEVREVLVKVGELPPIFGKNSAPDLAQLQQFESAIA
>NC_019693.1|WP_015151455.1|6817966_6818650_-|response-regulator-transcription-factor
MSAQLLLVDDEPGLREAVQAYLEDEGFSVQVASNANDGWDLLQQQHPDLVITDLMMPQVDGFEFLKRMREDPRFKVMPVVFLTARGMTGDRIQGYQAGCDAYLSKPFDPDELVAIVRNLLDRRAAASGEGEAPDLASLAREIGEIKSMLSGRHSIAQTPPPIKIDLTPREQSVLDLVAKGLMNKEIARNLDTSVRNVEKYVSRLFSKTGTNSRTELVRYALEHGLTE
>NC_019693.1|WP_015151453.1|6816879_6817623_+|PHP-domain-containing-protein
MTLLVSQQSISTQPAAQNKAALGRVFQALNPDSCPTTYNFHLHTVCSDGKLRPEEVMEQAISIGLKGLAITDHQSVRGYYAAQRWLDEWWINHSDLYQSDKTVAELPQAPQLWTGVEINAGLLDAEVHILGYAFNPEHPRMQPYLQSQVVTGPDYQASEVIHAIQAAGGLAVLAHPARYAKRSPADLIPEAASLGIDGIETYYAYKNPNPWKPSPKQTAKVYELGATYGLLNTCGTDTHGSNMLLRL
>NC_019693.1|WP_156824115.1|6814880_6816086_+|HetZ-related-protein
MTAGTPQVESPSGDTTEEPILILGMDTEQLSEQILDELSQKLKSGSKSAQEVALRIAKEVERICRKSNRIQNSGEVRSWQITLARHRLQKSLHYYKLGSRQGRVDLHAQLSSMVYRHVAHLHSRLSFQARYTLIEDFLQGFYIEVLRAFRREHEMPLTYTPRTQLELAEYMAFTEHYAKRRITLPGRYNQQLIVLRAQGFAQGQPPETLVDIEQAIEFPKGEDAEVQSRSYAAQQVREKMISEMVDPAEAVLRDRVVAELIQYLESQGQSDCIDYLVLKLQDLAAPEIDEILGLSARQRDYLQQRFKYHVEKFARSGHWKLVHQWLGADLDQNLGMPLQQWDTFLGELSEEQQQLLNLKRSGASDAEIAQEIKCTPKQVQKRWSALLEKAWQSRNTDSQEK
>NC_019693.1|WP_156823979.1|6814503_6814647_+|hypothetical-protein
MCQLSMRSGWNQPLSRLSTRKTSALWRSQPEKNRQWCILSRYSSMPV
>NC_019693.1|WP_015151451.1|6813438_6814074_+|threonylcarbamoyl-AMP-synthase
MATLYEIHPETPQVRKIEEVVDALKKGAVMLYPTDTVYAIGCDITVKGAIERVRQIKRLSNDKPLTFLCPSLSNIAAYATVTDSAYRIIKRLIPGPYTFLLPATKLVPKLVMDPKRKTTGIRVPDNQVCLDLLEALGNPIISTSAHLPSDFDHNGFIGKAELFDQVEKLVDVIIDTGEDPGYQVSTILDLTDNEPAIVRAGLGAELVANVI
>NC_019693.1|WP_015151450.1|6811963_6813280_-|nickel-pincer-cofactor-biosynthesis-protein-LarC
MKKIAYLQCPTGIAGDMFLGALVSAGVPFDYLREQLDCLGIGPEYQLRQEWVHRNTQQAMKIHVDRVETVAQSNRDPGDRHHHHEHEHHHHPHEHEHHHEHEHKHHHSHHPTRHLPEIEALIQGAQLPKRAETWSLQVFRTLAVAEGAVHGIAPEQVHFHEVGATDAIVDIVGTCLGLDWLGIEQLYCSPLPTGGGTVWAAHGRLPVPVPAVLSLFQSRQVPVYSNGIEKELVTPTGAAIAVTLATAFGNPPPMRIEQIGLGAGSRDLPIPNILRLWVGELTDNLPDSTVTESITVLETQIDDANPQAIAYTLERLFAAGALDAFTEGISMKKSRTGILLTVICHPEQQKTCEAVIFRETPTLGIRISTQQRSILHRELHTVSTPFGEVRVKVATDSQGTITNVQPEYEDCATIARSQDIPWQEVHRQGLLAWYRKLE
>NC_019693.1|WP_015151449.1|6811140_6811905_-|adenine-specific-DNA-methyltransferase
MKVFEIPGHQVIWGDVIDALEAGIEDNSINLIFADPPYNIGKIFNGKKEQWKGDDAYLDWCYQWLESCFRKLTTTGALYLMSATQYMPHLDIYLQKRLTILSRIVWHYDSSGMQAKKYFGSLYEPILFAVKNPQHYTFNADEIRVEAKTGAVRKLIDYRKSEPAPYCTTKIPGNVWYIPRVRYKMPEYRKHPTQKPEALLERIIKASSNPGDVVLDLFAGTFTTAAVSQRLERKSISIEREYEYVEIGLNRLGK
>NC_019693.1|WP_044198026.1|6810444_6810900_+|GNAT-family-N-acetyltransferase
MELIPGYRLRVGSSRDRYLLVKFLKLTYQELYPDYDFDHLAKTVDQYFAEETPLWWVEYPDNSEPVGCLWLGNAVDQVKGDRHAHIFVLYVAPEHRRRGLGSALMEYAENWARERGDRQMGLQVFLNNPPALNLYQKLGYQSHSVWMLKSL
>NC_019693.1|WP_044198024.1|6810165_6810417_+|hypothetical-protein
MSIIRSQILPFFIFLVFLVALVAVSARIFLPADMMAPAPIEEQVQPADRLSSVPSPKVAELPPSLSHLIKGLPEDRLFFNQES
>NC_019693.1|WP_044196019.1|6820711_6822820_-|AarF/ABC1/UbiB-kinase-family-protein
MDTKTVSPPSVKFQPDTVLEQSPGLSPFPERVNNLPVTVDIDSAATERVPLKSGAPYSDSNALLYDPVAITELYGDRPFLVWGRRFAILWPLLTLAFGIWRDKKWGRVKQNERKRAVKLRTTLTNLGPAFIKVGQALSTRPDLVPPLYLEELAKLQDQLPPFPNELAYQFIEEELGDRPSAIYAEITPDPVAAASLGQVYKGKLKTGETVAIKVQRPGLAESMGLDVYVLRQLAIWVQKNVKQVRSDLVAIMDEFGTRIYEEMDYNKEGENAERFAQLYGHLKDIYVPKIYWKYTGRRVLTMEWINGTKLTQIPALTAQGIDAKYLIEVGVQCSLRQLLEHGFFHADPHPGNLLATEDGKLAYLDFGMMSEVKPYQRYGLIQAVVHLVNRDFEGLAKDYVKLEFLTPETDLTPIIPALANVFNNALGASVAELNFKSITDQLSEIMYEYPFRVPAYYALIIRSLVTLEGIAINVDPNFKVLSKAYPYVAKRLLTDPSPELRGSLRDLLFKDGDFRWNRLENLLRNARESDDYDLSQGLNQALEFLFSERGEFIRDRLVEELVKSLDHLSRDAFNNATSVLREWVGWKGNKPTPAITSGDQEKMERIKRIWAIVQETPGFNTAEFVQKLAPFLIKPETQRMGQKIAGDLAQRMLARLIREVLIQEEPSNGNGKTSYPNRPQQQLPPSRTNGKVITYPNVTVRK
>NC_019693.1|WP_015151458.1|6823090_6823933_-|adenylate/guanylate-cyclase-domain-containing-protein
MVNPSGDRQEVSVLFSEISGYSSLTENLEASEVARLLQDYFESMLEAVNQYRQNHEQQIEVACIGNGLIVVFGAPQFLENHGWMALETAIAMHKKLDEFNHHRQEKNQPMIQMGIGINSDWTISNNIAENKSLQFSAVGDGVNLGNLLQGVSNQYGCNIVLGENTYRACEERIWARELDRIRMRSNYPPVALYQYLGLKGETISDESKKVMEHYDLGRQYYLNRKFAIAMGEFATVLEINSHDRAARLHLKRCQRLLKEPPNADWDGSWVAKKSWELAEH
>NC_019693.1|WP_015151459.1|6824054_6826727_-|GAF-domain-containing-protein
MTAASPNPKAWDHNNSSAGAVIDVTPQIVDGGKPDHQRSTSASVSEPESSPPSNSSGGGSLVQSKGTFTSFLAPLNKDSFTQVVKDVEGKLEVVNQTLSMLDSLLDAQGFDSILDEMLRSITLKTGELLGADRTTIFLLDEEKNELWSIIAKGAGGKPLEIRIPADKGIAGEVATFKKVVNIPFDFFDDSRSGAAKEQFKKTGYRTYTMLCLPLLNEQGALVAVVQLLNKLKKIHDADAELSERINAKGFTEEDERVFEEFAPSIRLILESSKSFYKATQRQRAAAALMSATQSLSKSSLDLEETLKKVMDEAKQLMNADRSTLWLIDRDKNDLWTKIPIGPRGELKEIRIPMGVGYAGTVGKTGEPLNIPFDLYDHPGCETSKRVDQQSGYRTCSLLCMPVFNSDGELIGVTQLVNKKKQGEHPPYEPTEWPEAPDCWKASFNRSDQEFMQAFNTQAGVALQNAKLFATVKQQEQMQRDILRSLSNGVISTDKSGNAIAANDSARQLLGLEVSDRIEGKSVRDLIQIKDGDFSKWFDAALTAKDDKSRQQYYPDQTLVAKDDKEQHSINLSINSIADASDRSNVYGALVVMEDISDEKRLKSTMYRYMTQEVAEQLLASGDTGLGGKRKEVSVLFSDIRSYTTLTEGMEAEDVVVMLNEYFESMVDAVFQYKGTLDKYIGDAIMAVFGSPLPLKDHAWCAVQTAIEMRRRLIEFNNNRTAAGKQILKIGIGIHSDEVVSGNIGSSKRMELTSIGDGVNLGSRLEGTSKMYGTDIVISEKTYSPCADKVYVRELDFITVKGKSEPVKIYELVGLRSDPISDHNMQIIESYTKGREFYLSRQFAKALQEFGKVLELDKNNKAASLQMDRCQHFVVEPPPDDWNGVWNLTEK
>NC_019693.1|WP_015151460.1|6827421_6829233_-|DNA-repair-protein-RecN
MLLSLRIENFALIDCLDLDFGKGLNVLTGETGAGKSIILDALDAVLGGKCTGRAIRTGTGRSLIEATFELEPPVAAYVREQEIELLDGTLLVVSRELVFGKGGAMRSRSRLNGVLVNRQLMEQLRDRLVEITAQGQTVQLGQPARQRDWLDAFAGPEVLAVRQGVVTRYGEANAARQALEDSRQSEQQRLQRIDLLDYQVKELSEANLNEADELEQLEQERQRLSHVVELQEQSDRVYQALYQQNDGSLAAADLLGEVEQTLQDMVAYDLELQGVLDMVNDALALAIEAGRQMSSYSSSLEADPDRLAEVEQRMAQLKQICRKYGPNLSAAIAYFHRIEAELEELTQADRAVEVLERLYQARQAELIQTCEELTHLRRTAALRLEQRLIEELKPLAMDNVQFQVQIEAVTPTSTGSDRIIFLFSPNPGEPLQPVAEIASGGEMSRFLLALQSCFVQVDNAATLVFDEIDAGVSGRVAGAIAQKLHQLSQGQQVLFVTHQPIVAAMADFHFRVNKQVIGSSEETPEATDPALKSAQSPGNGSTPPAPLAPEERTVVRVTALSSEQRREELAQLAGGQGASEAIAWAQSLLNQAASVRQIQTRSS
>NC_019693.1|WP_015151461.1|6829468_6829660_+|hypothetical-protein
MESGSPSARSSEPFPQKTLSNLLGGAIALLTLLLPLVAIATFSANRLPNLPSPPSYPLSGVRR
>NC_019693.1|WP_015151462.1|6830107_6830632_+|inorganic-diphosphatase
MDLTKIPAQPKPGLINVLIEIAGGSKNKYEFDKDLEAFALDRVLYASVQYPFDYGFIPNTLAEDGDPLDGMVIMDEPTFPGCVIAARPVGFLEMIDGGDPDEKILCVPDKDPRYAHVKSLKDIAPHRLEEIAEFFRTYKNLEKKKTEILGWHDVEKVMPLVEKCIKAGQQVGRN
>NC_019693.1|WP_015151463.1|6831111_6831501_+|aspartate-1-decarboxylase
MQRTLLLAKIHNCTLTDANLNYVGSISIDKKLMEAAGILPYEQVQVVNKSNGERLITYAIEAPGESGAIELNGAAARLGAPGDRLIIMTYGQFTPEEVTTYSPRVVLVDEQNRLLEVRRYEELHTFSLV
>NC_019693.1|WP_015151464.1|6831578_6832430_+|MBL-fold-metallo-hydrolase
METSLDSAFFIYFWGVRGSVATPGKETVHYGGNTSCVEMRVGGKRLIFDGGTGLRLLGTSLMPQMPVEAHLFFSHSHWDHIQGFPFFVPAFIPGNLFHVYGAVAPNGATMKQRLSDQMLHPNFPIPLQGMRSELKFYDLHPGDVVTIDDITIETAHLNHPSEALGYRVTWQGHTAVYCTDTEHYPDRLDENVLSLARNADIFIYDATYTDEEYYHPVTPKIGWGHSTWKEGIKIAKAAGVKHLVIFHHDPSHDDEFLADVESQIQAEFPDAFLAREGMKLNLI
>NC_019693.1|WP_015151465.1|6832800_6834078_+|transposase
MKLAYQYKLLPAYQQRCRMDKWLDMLRCQYNYLLAARFDWWEMNRCPVNACPLVCSIAEPRKQPEYYGQKRSLVSLKQERSWYADIHADVLQDMVKRVDLAFVRLIKGDKNGKRSGKPRFKGKNRYRTFAYQRVKPDCIQGNGVMLPKLGEMKFIQHRSIPDGFTIKRALVTKKADGWYVTLTLEDQAVPELPINEIQPTEANSIGVDAGLEYFIACSDGETKQPPKFYRQAEEKLGKLQAKRDARAKGSKPRRRLNERIAKLHQRIARQRQQWHFETAQELIDKAEVIFIEELKVSNMVRRNKPKQGDDGTFLPNGQSAKSGLNKSFADAGIAGFLNDILPYKAAKAGRLVVKVNPAGTSQHCAMCLNRVPKELSDRWHECPYCGASMPRDVNSGMLIKKVGLGVRLTIKRESLNGRRSPHRNA
>NC_019693.1|WP_015151466.1|6834128_6834926_+|pentapeptide-repeat-containing-protein
MAANNAHIKRLLETKQCQGGILNEANLGRFNLNKADLSGAKLLFANLNQTNLSHANLSGADLSFANLVDANLAHSDLSGLDGKGMNLFEAKLNHANLSGADLTFANCVNANFTDANLSGVDFKGANLIGAVLNHANLSGVQCAGANLGNAQLVEANLTNGDLSDTRLVDADLRDANLNGADLRNANLFNANLSGANLTGANLGGANLAHAKLDGAIGLYGSGMGMSGDRHSGMHQAGMAYIPLGQHPGAYPGGGSGLALPRPGMQ

Crispr_ID: NC_019693_75

• CRISPR_ID: NC_019693_75
• CRISPR_location: 7038938-7043138
• CRISPR_type: Orphan
• Repeat_type: NA:I-D,II-B
• Spacer_info: 57 spacers

Consensus repeat of NC_019693_75

Consensus_repeat	Method
GTTTCAATCC--------------------CTGAAAGGGATTAGAGGTCATTGGGAC	PILER-CR
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CRISPRCasFinder
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CRT
GTTTCAATCC--------------------CTGAAAGGGATTAGAGGTCATTGGGAC	PILER-CR

spacers of NC_019693_75

>75.1|7038975|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TACAATCAAACACCCCTACATCGCGCCCTTCCCCG
>75.2|7039047|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GAATGAAGCCTGCACCGGCGCGGATTCCATTCAA
>75.3|7039118|41|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CCGCTTCGGCTTCACGCTGTCCGGGTCATCTGGATTATAAA
>75.4|7039196|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GAGCATATTCTGCCCCAGCCGGAACCTTAATAAAT
>75.5|7039268|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GTGGAAGGGTTCCGCGAAAGTTCAACCAAAAATG
>75.6|7039339|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GACGTGGCAACTCCCCCGGCGCTACTACTCCCCC
>75.7|7039410|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GCTGCGAAACTTCTTCCCACATCTGAGGGTTGTTT
>75.8|7039482|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CTTGCGTACACTTGCGCTGGAATCACTCCCTATG
>75.9|7039553|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AAGTTCATTATTGCAAACACATTCACTAGAGCCA
>75.10|7039624|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TACTTATACGCAACGCATTGTATAGCAGCATAAC
>75.11|7039695|38|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AGCCTTAAACTGCGAGTTGACCGACCGGAAAAAATTGA
>75.12|7039770|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AAGCAAGAAAGGAATCAGGATCGGTGCGATCCTGGA
>75.13|7039843|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GGAGCAAGCTCAAGCAGACGCCAAGCTGAGAGAA
>75.14|7039914|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AACGCATTCTTTCCCATTTAATCTCTCCTACTATGT
>75.15|7039987|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GGCTAACCGTAAACGAAACACTGGAGGCGCTTAAT
>75.16|7040059|33|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CCGGTAGCAAGATGGGGCTTGCTAGTGACCTCA
>75.17|7040129|41|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTCGTAATATTCCGGTGGGTGCATCCCCTGGTAAGGGTACA
>75.18|7040207|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GTCCTCCCCCCGGCTCTTAGGGGGGCGGGCATTTTAA
>75.19|7040281|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AAGGGGGGGAGGATTGCCCTCTCTCAGGGCCTTGCAG
>75.20|7040355|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CGAATACTCATCGTGCGACTGGAGTAGTGATGAG
>75.21|7040426|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CTATCGGACCAGAATCTGGATTTACCGGCTCAATC
>75.22|7040498|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CACCAGACGCACGGACCCATCGGCCCAGACATCG
>75.23|7040569|38|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ATCCGAATGATCGGACCTTAAATAATTTCTGCCATTGG
>75.24|7040644|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GGACGCTTCTCCTTGAAGCCTTAAACGAAGTAAA
>75.25|7040715|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AGTTGAGGAATTCTCGACTGAGGAGATTGAGGAG
>75.26|7040786|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ACAAAAATCGAGGAAAACAAACTTTTCAGCGAGTGG
>75.27|7040859|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AAATATCAACTCAAAAACTTCTATCGCGACTATC
>75.28|7040930|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GCAATCATCTGACTCGCCTTGTAGATAGGCTTTG
>75.29|7041001|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GCTTATCAATCCGACGAATCCGGGGAGGGAATGCGG
>75.30|7041074|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTGAGACAACACGAAGCTACCGGAGAATCCATCA
>75.31|7041145|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AGAAAAAACCCTTTTCTGGAACTCTTATGCTGTCCCG
>75.32|7041219|38|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GACTTTGCTTTGGTGAAATCGACTCACCAACAATCCGA
>75.33|7041294|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CCGATCACCAGGGAACCATCCAAAAATAGGGAGG
>75.34|7041365|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTTGTCTTACCCGACAGAGATGATTAATCGCCATGA
>75.35|7041438|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GCCGCTGCAAGTGGCTTCATTGCAAGCTCAATGAA
>75.36|7041510|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GTTCATGCGAGAAAAGTTGGGCGGTAAATAATAAG
>75.37|7041582|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CAGTAATTTGTCTTACCCGACCGACTGCCCGACAAG
>75.38|7041655|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ATTACAGGGGGAGGAAGCGGGGATTTGCATATAACAG
>75.39|7041729|40|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AGGAATATCGTGGTGATAGTATCCGGGCCGGTAGGTCCCA
>75.40|7041806|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ACCCAACGCAGGCTCAAAGCTGAGAGAGAAGCCAA
>75.41|7041878|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CATACAGGGAGCATTTAAAATCAGCAAAATGATTT
>75.42|7041950|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ACTACTCCATAAATATAAGGATTTGAATTAAATAAAG
>75.43|7042024|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TGGGGAATGAATAGAAAACAGATACTAAAGGAATAAA
>75.44|7042098|41|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GTTTCAGGGATTCAGTCAATTGGGGCCACTGCGGTTTCCTG
>75.45|7042176|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TAGCGAGACAACGTTCAATTTTTGGGCATACCTTGC
>75.46|7042249|38|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TCATTATTACAAACAGACAGATGGGGGATTTTCAAATG
>75.47|7042324|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AAATCAACTTGCGATGCTTGTTAAACTGCTTGCC
>75.48|7042395|35|NC_019693|CRISPRCasFinder,CRT
TAATTGAATCATCTGCCCCGGCACGATTATCGGCC
>75.49|7042467|45|NC_019693|CRISPRCasFinder,CRT,PILER-CR
TTGGAATATGCCCTCCTCTGGATCGGTAATAGTTGCGATAACCCG
>75.50|7042549|35|NC_019693|CRISPRCasFinder,CRT,PILER-CR
GCAAGCGCGGCAGGGGTTGATCCAGGGATTGTGCA
>75.51|7042621|39|NC_019693|CRISPRCasFinder,CRT,PILER-CR
ATCGAAAAAACTGCATTCTTCCAGGGGCTTTCCACAAAT
>75.52|7042697|34|NC_019693|CRISPRCasFinder,CRT,PILER-CR
GTAACTCAGCAGGGTCCAACTCTGGGAGGGGGAT
>75.53|7042768|43|NC_019693|CRISPRCasFinder,CRT,PILER-CR
ATCGATATTACTACCCCTGCTGCTGACTCAAATCCCGTCCCAA
>75.54|7042848|40|NC_019693|CRISPRCasFinder,CRT,PILER-CR
ACACGAACATAGTCAGGGCCAACAACAGCAGCTTTTACAA
>75.55|7042925|36|NC_019693|CRISPRCasFinder,CRT
TGGAATTTTTCATATCATCTGGAACCATCTCGATCC
>75.56|7042998|33|NC_019693|CRISPRCasFinder,CRT
TATTTAGTTAACTCCTTAGTTAACTGAGTCTTC
>75.57|7043068|34|NC_019693|CRISPRCasFinder,CRT
CTAAATATCTGGCGTAATATTCATCCATTGCTTG

CRISPR arrays and Neighbor proteins around NC_019693_75

CRISPR arrays

The CRISPR arrays of NC_019693_75

>merge|NC_019693|75|7038938-7043138|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTACAATCAAACACCCCTACATCGCGCCCTTCCCCGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGAATGAAGCCTGCACCGGCGCGGATTCCATTCAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCCGCTTCGGCTTCACGCTGTCCGGGTCATCTGGATTATAAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGAGCATATTCTGCCCCAGCCGGAACCTTAATAAATGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGTGGAAGGGTTCCGCGAAAGTTCAACCAAAAATGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGACGTGGCAACTCCCCCGGCGCTACTACTCCCCCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGCTGCGAAACTTCTTCCCACATCTGAGGGTTGTTTGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCTTGCGTACACTTGCGCTGGAATCACTCCCTATGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAAGTTCATTATTGCAAACACATTCACTAGAGCCAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTACTTATACGCAACGCATTGTATAGCAGCATAACGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAGCCTTAAACTGCGAGTTGACCGACCGGAAAAAATTGAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAAGCAAGAAAGGAATCAGGATCGGTGCGATCCTGGAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGGAGCAAGCTCAAGCAGACGCCAAGCTGAGAGAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAACGCATTCTTTCCCATTTAATCTCTCCTACTATGTGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGGCTAACCGTAAACGAAACACTGGAGGCGCTTAATGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCCGGTAGCAAGATGGGGCTTGCTAGTGACCTCAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTTCGTAATATTCCGGTGGGTGCATCCCCTGGTAAGGGTACAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGTCCTCCCCCCGGCTCTTAGGGGGGCGGGCATTTTAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAAGGGGGGGAGGATTGCCCTCTCTCAGGGCCTTGCAGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCGAATACTCATCGTGCGACTGGAGTAGTGATGAGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCTATCGGACCAGAATCTGGATTTACCGGCTCAATCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCACCAGACGCACGGACCCATCGGCCCAGACATCGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACATCCGAATGATCGGACCTTAAATAATTTCTGCCATTGGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGGACGCTTCTCCTTGAAGCCTTAAACGAAGTAAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAGTTGAGGAATTCTCGACTGAGGAGATTGAGGAGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACACAAAAATCGAGGAAAACAAACTTTTCAGCGAGTGGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAAATATCAACTCAAAAACTTCTATCGCGACTATCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGCAATCATCTGACTCGCCTTGTAGATAGGCTTTGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGCTTATCAATCCGACGAATCCGGGGAGGGAATGCGGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTTGAGACAACACGAAGCTACCGGAGAATCCATCAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAGAAAAAACCCTTTTCTGGAACTCTTATGCTGTCCCGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGACTTTGCTTTGGTGAAATCGACTCACCAACAATCCGAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCCGATCACCAGGGAACCATCCAAAAATAGGGAGGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTTTGTCTTACCCGACAGAGATGATTAATCGCCATGAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGCCGCTGCAAGTGGCTTCATTGCAAGCTCAATGAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGTTCATGCGAGAAAAGTTGGGCGGTAAATAATAAGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCAGTAATTTGTCTTACCCGACCGACTGCCCGACAAGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACATTACAGGGGGAGGAAGCGGGGATTTGCATATAACAGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAGGAATATCGTGGTGATAGTATCCGGGCCGGTAGGTCCCAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACACCCAACGCAGGCTCAAAGCTGAGAGAGAAGCCAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCATACAGGGAGCATTTAAAATCAGCAAAATGATTTGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACACTACTCCATAAATATAAGGATTTGAATTAAATAAAGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTGGGGAATGAATAGAAAACAGATACTAAAGGAATAAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGTTTCAGGGATTCAGTCAATTGGGGCCACTGCGGTTTCCTGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTAGCGAGACAACGTTCAATTTTTGGGCATACCTTGCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTCATTATTACAAACAGACAGATGGGGGATTTTCAAATGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAAATCAACTTGCGATGCTTGTTAAACTGCTTGCCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTAATTGAATCATCTGCCCCGGCACGATTATCGGCCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTTGGAATATGCCCTCCTCTGGATCGGTAATAGTTGCGATAACCCGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGCAAGCGCGGCAGGGGTTGATCCAGGGATTGTGCAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACATCGAAAAAACTGCATTCTTCCAGGGGCTTTCCACAAATGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGTAACTCAGCAGGGTCCAACTCTGGGAGGGGGATGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACATCGATATTACTACCCCTGCTGCTGACTCAAATCCCGTCCCAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACACACGAACATAGTCAGGGCCAACAACAGCAGCTTTTACAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTGGAATTTTTCATATCATCTGGAACCATCTCGATCCGTCTCAATGGCCCTAAATCCCTTTCAGGCATTGAAACTATTTAGTTAACTCCTTAGTTAACTGAGTCTTCGTCTCAATGGCCCTAAATCCCTTTCAGGGATTGAAACCTAAATATCTGGCGTAATATTCATCCATTGCTTGGTTTCAATGGACCTAAATCCCTTTCAAGAATTGAAAC

>NC_019693|75|9|7038938-7042394|PILER-CR
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TACAATCAAACACCCCTACATCGCGCCCTTCCCCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAATGAAGCCTGCACCGGCGCGGATTCCATTCAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCGCTTCGGCTTCACGCTGTCCGGGTCATCTGGATTATAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAGCATATTCTGCCCCAGCCGGAACCTTAATAAAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTGGAAGGGTTCCGCGAAAGTTCAACCAAAAATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GACGTGGCAACTCCCCCGGCGCTACTACTCCCCC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCTGCGAAACTTCTTCCCACATCTGAGGGTTGTTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTTGCGTACACTTGCGCTGGAATCACTCCCTATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAGTTCATTATTGCAAACACATTCACTAGAGCCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TACTTATACGCAACGCATTGTATAGCAGCATAAC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AGCCTTAAACTGCGAGTTGACCGACCGGAAAAAATTGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAGCAAGAAAGGAATCAGGATCGGTGCGATCCTGGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GGAGCAAGCTCAAGCAGACGCCAAGCTGAGAGAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AACGCATTCTTTCCCATTTAATCTCTCCTACTATGT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GGCTAACCGTAAACGAAACACTGGAGGCGCTTAAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCGGTAGCAAGATGGGGCTTGCTAGTGACCTCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTCGTAATATTCCGGTGGGTGCATCCCCTGGTAAGGGTACA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTCCTCCCCCCGGCTCTTAGGGGGGCGGGCATTTTAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAGGGGGGGAGGATTGCCCTCTCTCAGGGCCTTGCAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CGAATACTCATCGTGCGACTGGAGTAGTGATGAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTATCGGACCAGAATCTGGATTTACCGGCTCAATC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CACCAGACGCACGGACCCATCGGCCCAGACATCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATCCGAATGATCGGACCTTAAATAATTTCTGCCATTGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GGACGCTTCTCCTTGAAGCCTTAAACGAAGTAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AGTTGAGGAATTCTCGACTGAGGAGATTGAGGAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACAAAAATCGAGGAAAACAAACTTTTCAGCGAGTGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAATATCAACTCAAAAACTTCTATCGCGACTATC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCAATCATCTGACTCGCCTTGTAGATAGGCTTTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCTTATCAATCCGACGAATCCGGGGAGGGAATGCGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGAGACAACACGAAGCTACCGGAGAATCCATCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AGAAAAAACCCTTTTCTGGAACTCTTATGCTGTCCCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GACTTTGCTTTGGTGAAATCGACTCACCAACAATCCGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCGATCACCAGGGAACCATCCAAAAATAGGGAGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGTCTTACCCGACAGAGATGATTAATCGCCATGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCCGCTGCAAGTGGCTTCATTGCAAGCTCAATGAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTTCATGCGAGAAAAGTTGGGCGGTAAATAATAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CAGTAATTTGTCTTACCCGACCGACTGCCCGACAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATTACAGGGGGAGGAAGCGGGGATTTGCATATAACAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AGGAATATCGTGGTGATAGTATCCGGGCCGGTAGGTCCCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACCCAACGCAGGCTCAAAGCTGAGAGAGAAGCCAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CATACAGGGAGCATTTAAAATCAGCAAAATGATTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACTACTCCATAAATATAAGGATTTGAATTAAATAAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGGGGAATGAATAGAAAACAGATACTAAAGGAATAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTTTCAGGGATTCAGTCAATTGGGGCCACTGCGGTTTCCTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAGCGAGACAACGTTCAATTTTTGGGCATACCTTGC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TCATTATTACAAACAGACAGATGGGGGATTTTCAAATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAATCAACTTGCGATGCTTGTTAAACTGCTTGCC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTAATTGAATCATCTGCCCCGGCACGATTATCGGCCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGGAATATGCCCTCCTCTGGATCGGTAATAGTTGCGATAACCCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCAAGCGCGGCAGGGGTTGATCCAGGGATTGTGCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATCGAAAAAACTGCATTCTTCCAGGGGCTTTCCACAAAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTAACTCAGCAGGGTCCAACTCTGGGAGGGGGAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATCGATATTACTACCCCTGCTGCTGACTCAAATCCCGTCCCAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACACGAACATAGTCAGGGCCAACAACAGCAGCTTTTACAA


>NC_019693|75|73|7038938-7043138|CRISPRCasFinder
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TACAATCAAACACCCCTACATCGCGCCCTTCCCCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAATGAAGCCTGCACCGGCGCGGATTCCATTCAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCGCTTCGGCTTCACGCTGTCCGGGTCATCTGGATTATAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAGCATATTCTGCCCCAGCCGGAACCTTAATAAAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTGGAAGGGTTCCGCGAAAGTTCAACCAAAAATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GACGTGGCAACTCCCCCGGCGCTACTACTCCCCC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCTGCGAAACTTCTTCCCACATCTGAGGGTTGTTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTTGCGTACACTTGCGCTGGAATCACTCCCTATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAGTTCATTATTGCAAACACATTCACTAGAGCCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TACTTATACGCAACGCATTGTATAGCAGCATAAC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AGCCTTAAACTGCGAGTTGACCGACCGGAAAAAATTGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAGCAAGAAAGGAATCAGGATCGGTGCGATCCTGGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GGAGCAAGCTCAAGCAGACGCCAAGCTGAGAGAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AACGCATTCTTTCCCATTTAATCTCTCCTACTATGT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GGCTAACCGTAAACGAAACACTGGAGGCGCTTAAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCGGTAGCAAGATGGGGCTTGCTAGTGACCTCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTCGTAATATTCCGGTGGGTGCATCCCCTGGTAAGGGTACA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTCCTCCCCCCGGCTCTTAGGGGGGCGGGCATTTTAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAGGGGGGGAGGATTGCCCTCTCTCAGGGCCTTGCAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CGAATACTCATCGTGCGACTGGAGTAGTGATGAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTATCGGACCAGAATCTGGATTTACCGGCTCAATC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CACCAGACGCACGGACCCATCGGCCCAGACATCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATCCGAATGATCGGACCTTAAATAATTTCTGCCATTGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GGACGCTTCTCCTTGAAGCCTTAAACGAAGTAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AGTTGAGGAATTCTCGACTGAGGAGATTGAGGAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACAAAAATCGAGGAAAACAAACTTTTCAGCGAGTGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAATATCAACTCAAAAACTTCTATCGCGACTATC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCAATCATCTGACTCGCCTTGTAGATAGGCTTTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCTTATCAATCCGACGAATCCGGGGAGGGAATGCGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGAGACAACACGAAGCTACCGGAGAATCCATCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AGAAAAAACCCTTTTCTGGAACTCTTATGCTGTCCCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GACTTTGCTTTGGTGAAATCGACTCACCAACAATCCGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCGATCACCAGGGAACCATCCAAAAATAGGGAGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGTCTTACCCGACAGAGATGATTAATCGCCATGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCCGCTGCAAGTGGCTTCATTGCAAGCTCAATGAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTTCATGCGAGAAAAGTTGGGCGGTAAATAATAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CAGTAATTTGTCTTACCCGACCGACTGCCCGACAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATTACAGGGGGAGGAAGCGGGGATTTGCATATAACAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AGGAATATCGTGGTGATAGTATCCGGGCCGGTAGGTCCCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACCCAACGCAGGCTCAAAGCTGAGAGAGAAGCCAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CATACAGGGAGCATTTAAAATCAGCAAAATGATTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACTACTCCATAAATATAAGGATTTGAATTAAATAAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGGGGAATGAATAGAAAACAGATACTAAAGGAATAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTTTCAGGGATTCAGTCAATTGGGGCCACTGCGGTTTCCTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAGCGAGACAACGTTCAATTTTTGGGCATACCTTGC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TCATTATTACAAACAGACAGATGGGGGATTTTCAAATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAATCAACTTGCGATGCTTGTTAAACTGCTTGCC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAATTGAATCATCTGCCCCGGCACGATTATCGGCC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGGAATATGCCCTCCTCTGGATCGGTAATAGTTGCGATAACCCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCAAGCGCGGCAGGGGTTGATCCAGGGATTGTGCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATCGAAAAAACTGCATTCTTCCAGGGGCTTTCCACAAAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTAACTCAGCAGGGTCCAACTCTGGGAGGGGGAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATCGATATTACTACCCCTGCTGCTGACTCAAATCCCGTCCCAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACACGAACATAGTCAGGGCCAACAACAGCAGCTTTTACAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGGAATTTTTCATATCATCTGGAACCATCTCGATCC
GTCTCAATGGCCCTAAATCCCTTTCAGGCATTGAAAC	TATTTAGTTAACTCCTTAGTTAACTGAGTCTTC
GTCTCAATGGCCCTAAATCCCTTTCAGGGATTGAAAC	CTAAATATCTGGCGTAATATTCATCCATTGCTTG
GTTTCAATGGACCTAAATCCCTTTCAAGAATTGAAAC

>NC_019693|75|8|7038938-7043138|CRT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TACAATCAAACACCCCTACATCGCGCCCTTCCCCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAATGAAGCCTGCACCGGCGCGGATTCCATTCAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCGCTTCGGCTTCACGCTGTCCGGGTCATCTGGATTATAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAGCATATTCTGCCCCAGCCGGAACCTTAATAAAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTGGAAGGGTTCCGCGAAAGTTCAACCAAAAATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GACGTGGCAACTCCCCCGGCGCTACTACTCCCCC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCTGCGAAACTTCTTCCCACATCTGAGGGTTGTTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTTGCGTACACTTGCGCTGGAATCACTCCCTATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAGTTCATTATTGCAAACACATTCACTAGAGCCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TACTTATACGCAACGCATTGTATAGCAGCATAAC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AGCCTTAAACTGCGAGTTGACCGACCGGAAAAAATTGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAGCAAGAAAGGAATCAGGATCGGTGCGATCCTGGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GGAGCAAGCTCAAGCAGACGCCAAGCTGAGAGAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AACGCATTCTTTCCCATTTAATCTCTCCTACTATGT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GGCTAACCGTAAACGAAACACTGGAGGCGCTTAAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCGGTAGCAAGATGGGGCTTGCTAGTGACCTCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTCGTAATATTCCGGTGGGTGCATCCCCTGGTAAGGGTACA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTCCTCCCCCCGGCTCTTAGGGGGGCGGGCATTTTAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAGGGGGGGAGGATTGCCCTCTCTCAGGGCCTTGCAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CGAATACTCATCGTGCGACTGGAGTAGTGATGAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTATCGGACCAGAATCTGGATTTACCGGCTCAATC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CACCAGACGCACGGACCCATCGGCCCAGACATCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATCCGAATGATCGGACCTTAAATAATTTCTGCCATTGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GGACGCTTCTCCTTGAAGCCTTAAACGAAGTAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AGTTGAGGAATTCTCGACTGAGGAGATTGAGGAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACAAAAATCGAGGAAAACAAACTTTTCAGCGAGTGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAATATCAACTCAAAAACTTCTATCGCGACTATC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCAATCATCTGACTCGCCTTGTAGATAGGCTTTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCTTATCAATCCGACGAATCCGGGGAGGGAATGCGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGAGACAACACGAAGCTACCGGAGAATCCATCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AGAAAAAACCCTTTTCTGGAACTCTTATGCTGTCCCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GACTTTGCTTTGGTGAAATCGACTCACCAACAATCCGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCGATCACCAGGGAACCATCCAAAAATAGGGAGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGTCTTACCCGACAGAGATGATTAATCGCCATGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCCGCTGCAAGTGGCTTCATTGCAAGCTCAATGAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTTCATGCGAGAAAAGTTGGGCGGTAAATAATAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CAGTAATTTGTCTTACCCGACCGACTGCCCGACAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATTACAGGGGGAGGAAGCGGGGATTTGCATATAACAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AGGAATATCGTGGTGATAGTATCCGGGCCGGTAGGTCCCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACCCAACGCAGGCTCAAAGCTGAGAGAGAAGCCAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CATACAGGGAGCATTTAAAATCAGCAAAATGATTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACTACTCCATAAATATAAGGATTTGAATTAAATAAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGGGGAATGAATAGAAAACAGATACTAAAGGAATAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTTTCAGGGATTCAGTCAATTGGGGCCACTGCGGTTTCCTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAGCGAGACAACGTTCAATTTTTGGGCATACCTTGC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TCATTATTACAAACAGACAGATGGGGGATTTTCAAATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAATCAACTTGCGATGCTTGTTAAACTGCTTGCC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAATTGAATCATCTGCCCCGGCACGATTATCGGCC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGGAATATGCCCTCCTCTGGATCGGTAATAGTTGCGATAACCCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCAAGCGCGGCAGGGGTTGATCCAGGGATTGTGCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATCGAAAAAACTGCATTCTTCCAGGGGCTTTCCACAAAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTAACTCAGCAGGGTCCAACTCTGGGAGGGGGAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATCGATATTACTACCCCTGCTGCTGACTCAAATCCCGTCCCAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACACGAACATAGTCAGGGCCAACAACAGCAGCTTTTACAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGGAATTTTTCATATCATCTGGAACCATCTCGATCC
GTCTCAATGGCCCTAAATCCCTTTCAGGCATTGAAAC	TATTTAGTTAACTCCTTAGTTAACTGAGTCTTC
GTCTCAATGGCCCTAAATCCCTTTCAGGGATTGAAAC	CTAAATATCTGGCGTAATATTCATCCATTGCTTG
GTTTCAATGGACCTAAATCCCTTTCAAGAATTGAAAC

>NC_019693|75|10|7042430-7042924|PILER-CR
	TACAATCAAACACCCCTACATCGCGCCCTTCCCCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAATGAAGCCTGCACCGGCGCGGATTCCATTCAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCGCTTCGGCTTCACGCTGTCCGGGTCATCTGGATTATAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAGCATATTCTGCCCCAGCCGGAACCTTAATAAAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTGGAAGGGTTCCGCGAAAGTTCAACCAAAAATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GACGTGGCAACTCCCCCGGCGCTACTACTCCCCC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCTGCGAAACTTCTTCCCACATCTGAGGGTTGTTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTTGCGTACACTTGCGCTGGAATCACTCCCTATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAGTTCATTATTGCAAACACATTCACTAGAGCCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TACTTATACGCAACGCATTGTATAGCAGCATAAC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AGCCTTAAACTGCGAGTTGACCGACCGGAAAAAATTGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAGCAAGAAAGGAATCAGGATCGGTGCGATCCTGGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GGAGCAAGCTCAAGCAGACGCCAAGCTGAGAGAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AACGCATTCTTTCCCATTTAATCTCTCCTACTATGT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GGCTAACCGTAAACGAAACACTGGAGGCGCTTAAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCGGTAGCAAGATGGGGCTTGCTAGTGACCTCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTCGTAATATTCCGGTGGGTGCATCCCCTGGTAAGGGTACA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTCCTCCCCCCGGCTCTTAGGGGGGCGGGCATTTTAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAGGGGGGGAGGATTGCCCTCTCTCAGGGCCTTGCAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CGAATACTCATCGTGCGACTGGAGTAGTGATGAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTATCGGACCAGAATCTGGATTTACCGGCTCAATC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CACCAGACGCACGGACCCATCGGCCCAGACATCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATCCGAATGATCGGACCTTAAATAATTTCTGCCATTGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GGACGCTTCTCCTTGAAGCCTTAAACGAAGTAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AGTTGAGGAATTCTCGACTGAGGAGATTGAGGAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACAAAAATCGAGGAAAACAAACTTTTCAGCGAGTGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAATATCAACTCAAAAACTTCTATCGCGACTATC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCAATCATCTGACTCGCCTTGTAGATAGGCTTTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCTTATCAATCCGACGAATCCGGGGAGGGAATGCGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGAGACAACACGAAGCTACCGGAGAATCCATCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AGAAAAAACCCTTTTCTGGAACTCTTATGCTGTCCCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GACTTTGCTTTGGTGAAATCGACTCACCAACAATCCGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCGATCACCAGGGAACCATCCAAAAATAGGGAGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGTCTTACCCGACAGAGATGATTAATCGCCATGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCCGCTGCAAGTGGCTTCATTGCAAGCTCAATGAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTTCATGCGAGAAAAGTTGGGCGGTAAATAATAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CAGTAATTTGTCTTACCCGACCGACTGCCCGACAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATTACAGGGGGAGGAAGCGGGGATTTGCATATAACAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AGGAATATCGTGGTGATAGTATCCGGGCCGGTAGGTCCCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACCCAACGCAGGCTCAAAGCTGAGAGAGAAGCCAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CATACAGGGAGCATTTAAAATCAGCAAAATGATTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACTACTCCATAAATATAAGGATTTGAATTAAATAAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGGGGAATGAATAGAAAACAGATACTAAAGGAATAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTTTCAGGGATTCAGTCAATTGGGGCCACTGCGGTTTCCTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAGCGAGACAACGTTCAATTTTTGGGCATACCTTGC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TCATTATTACAAACAGACAGATGGGGGATTTTCAAATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAATCAACTTGCGATGCTTGTTAAACTGCTTGCC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTAATTGAATCATCTGCCCCGGCACGATTATCGGCCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGGAATATGCCCTCCTCTGGATCGGTAATAGTTGCGATAACCCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCAAGCGCGGCAGGGGTTGATCCAGGGATTGTGCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATCGAAAAAACTGCATTCTTCCAGGGGCTTTCCACAAAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GTAACTCAGCAGGGTCCAACTCTGGGAGGGGGAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATCGATATTACTACCCCTGCTGCTGACTCAAATCCCGTCCCAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACACGAACATAGTCAGGGCCAACAACAGCAGCTTTTACAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015151625.1|7056239_7057247_+|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl|CDD|224007
NC_019693.1|WP_015151610.1|7024458_7026423_-|M48-family-metalloprotease	unknown	unknown	gnl|CDD|320692
NC_019693.1|WP_015151626.1|7057494_7059450_+|DUF1929-domain-containing-protein	unknown	unknown	gnl|CDD|199882
NC_019693.1|WP_083896831.1|7044798_7046103_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NC_019693.1|WP_015151616.1|7037195_7038098_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151613.1|7029281_7033064_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|182070
NC_019693.1|WP_015151622.1|7053629_7054298_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_019693.1|WP_015151611.1|7026867_7027740_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293801
NC_019693.1|WP_015151621.1|7053047_7053551_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_156824118.1|7048515_7049733_+|hypothetical-protein	unknown	unknown	gnl|CDD|367389
NC_019693.1|WP_015151609.1|7023647_7024340_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151619.1|7049875_7051693_+|GMC-family-oxidoreductase	unknown	unknown	gnl|CDD|225186
NC_019693.1|WP_015151614.1|7034691_7035654_+|7,8-didemethyl-8-hydroxy-5-deazariboflavin-synthase-subunit-CofG	unknown	unknown	gnl|CDD|180485
NC_019693.1|WP_156823989.1|7054560_7055568_+|myo-inosose-2-dehydratase	unknown	unknown	gnl|CDD|275172
NC_019693.1|WP_015151620.1|7051756_7052851_+|hypothetical-protein	unknown	unknown	gnl|CDD|372375
NC_019693.1|WP_015151624.1|7055694_7056078_+|DUF4440-domain-containing-protein	unknown	unknown	gnl|CDD|226769
NC_019693.1|WP_015149763.1|7033460_7034543_-|photosystem-II-q(b)-protein	unknown	unknown	gnl|CDD|130221
NC_019693.1|WP_015151612.1|7027880_7028993_-|chorismate-synthase	unknown	unknown	gnl|CDD|215402
NC_019693.1|WP_044196058.1|7022798_7023584_+|D-alanyl-D-alanine-carboxypeptidase-family-protein	unknown	unknown	gnl|CDD|367124
NC_019693.1|WP_015151615.1|7036072_7036870_-|3',5'-cyclic-AMP-phosphodiesterase	unknown	unknown	gnl|CDD|182997

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015151625.1|7056239_7057247_+|sugar-phosphate-isomerase/epimerase	gnl|CDD|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	6.9873e-25
NC_019693.1|WP_015151610.1|7024458_7026423_-|M48-family-metalloprotease	gnl|CDD|320692	cd07333, M48C_bepA_like, Peptidase M48C Ste24p bepA-like, integral membrane protein. This family contains peptidase M48C Ste24p protease bepA (formerly yfgC)-like proteins considered to be putative metallopeptidases, containing a zinc-binding motif, HEXXH, and a COOH-terminal ER retrieval signal (KKXX). They proteolytically remove the C-terminal three residues of farnesylated proteins. They are integral membrane proteins associated with the endoplasmic reticulum and golgi, binding one zinc ion per subunit. In eukaryotes, Ste24p is required for the first NH2-terminal proteolytic processing event within the a-factor precursor, which takes place after COOH-terminal CAAX modification (C is cysteine; A is usually aliphatic; X is one of several amino acids) is complete. Mutation studies have shown that the HEXXH protease motif, which is extracellular but adjacent to a transmembrane domain and therefore close to the membrane surface, is critical for Ste24p activity. Several members of this family also contain tetratricopeptide (TPR) repeat motifs, which are involved in a variety of functions including protein-protein interactions. BepA has been shown to possess protease activity and is responsible for the degradation of incorrectly folded LptD, an essential outer-membrane protein (OMP) involved in OM transport and assembly of lipopolysaccharide. Overexpression of the bepA protease causes abnormal biofilm architecture.	5.03431e-63
NC_019693.1|WP_015151626.1|7057494_7059450_+|DUF1929-domain-containing-protein	gnl|CDD|199882	cd02851, E_set_GO_C, C-terminal Early set domain associated with the catalytic domain of galactose oxidase. E or "early" set domains are associated with the catalytic domain of galactose oxidase at the C-terminal end. Galactose oxidase is an extracellular monomeric enzyme which catalyzes the stereospecific oxidation of a broad range of primary alcohol substrates and possesses a unique mononuclear copper site essential for catalyzing a two-electron transfer reaction during the oxidation of primary alcohols to corresponding aldehydes. The second redox active center necessary for the reaction was found to be situated at a tyrosine residue. The C-terminal domain of galactose oxidase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others.	4.4548e-30
NC_019693.1|WP_083896831.1|7044798_7046103_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	2.40712e-32
NC_019693.1|WP_015151619.1|7049875_7051693_+|GMC-family-oxidoreductase	gnl|CDD|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	5.07407e-82
NC_019693.1|WP_015151613.1|7029281_7033064_-|PAS-domain-S-box-protein	gnl|CDD|182070	PRK09776, PRK09776, putative diguanylate cyclase; Provisional.	7.03934e-61
NC_019693.1|WP_015151622.1|7053629_7054298_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	3.14648e-27
NC_019693.1|WP_015151611.1|7026867_7027740_-|MBL-fold-metallo-hydrolase	gnl|CDD|293801	cd07715, TaR3-like_MBL-fold, MBL-fold metallo-hydrolase domain of Myxococcus xanthus TaR3 and related proteins; MBL-fold metallo-hydrolase domain. Myxococcus xanthus Tar3 may function as an ammonium regulator/effector protein involved in biosynthesis of the antibiotic TA. Some are members of this subgroup are annotated as ribonucleases. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	3.10389e-106
NC_019693.1|WP_156824118.1|7048515_7049733_+|hypothetical-protein	gnl|CDD|367389	pfam03200, Glyco_hydro_63, Glycosyl hydrolase family 63 C-terminal domain. This is a family of eukaryotic enzymes belonging to glycosyl hydrolase family 63. They catalyze the specific cleavage of the non-reducing terminal glucose residue from Glc(3)Man(9)GlcNAc(2). Mannosyl oligosaccharide glucosidase EC:3.2.1.106 is the first enzyme in the N-linked oligosaccharide processing pathway. This family represents the C-terminal catalytic domain.	1.08574e-06
NC_019693.1|WP_015151614.1|7034691_7035654_+|7,8-didemethyl-8-hydroxy-5-deazariboflavin-synthase-subunit-CofG	gnl|CDD|180485	PRK06245, cofG, FO synthase subunit 1; Reviewed.	7.54844e-166
NC_019693.1|WP_156823989.1|7054560_7055568_+|myo-inosose-2-dehydratase	gnl|CDD|275172	TIGR04379, myo-inositol_catabolism_protein, myo-inosose-2 dehydratase. Members of this family include the enzyme myo-inosose-2 dehydratase, product of the gene iolE, as found in inositol utilization cassettes in many species. [Energy metabolism, Sugars].	1.51546e-124
NC_019693.1|WP_015151620.1|7051756_7052851_+|hypothetical-protein	gnl|CDD|372375	pfam12902, Ferritin-like, Ferritin-like. This is a family of bacterial ferritin-like substances that also includes a C-terminal domain of VioB, polyketide synthase enzymes, that make up one of the key components of the violacein biosynthesis pathway. Violacein is a purple-coloured, broad-spectrum antibacterial pigment.	6.16609e-76
NC_019693.1|WP_015151624.1|7055694_7056078_+|DUF4440-domain-containing-protein	gnl|CDD|226769	COG4319, COG4319, Ketosteroid isomerase homolog [Function unknown].	6.71544e-22
NC_019693.1|WP_015149763.1|7033460_7034543_-|photosystem-II-q(b)-protein	gnl|CDD|130221	TIGR01151, Photosystem_QB_protein, photosystem II, DI subunit (also called Q(B)). This model describes the Photosystem II, DI subunit (also called Q(B)) in bacterial and its equivalents in chloroplast of algae and higher plants. Photosystem II is many ways functionally equivalent to bacterial reaction center. At the core of Photosystem II are several light harvesting cofactors including plastoquinones, pheophytins, phyloquinones etc. These cofactors are intimately associated with the polypeptides, which principally including subunits DI, DII, Cyt.b, Cyt.f and iron-sulphur protein. Together they participate in the electron transfer reactions that lead to the net production of the reducting equivalents in the form of NADPH, which are used for reduction of CO2 to carbohydrates(C6H1206). Phosystem II operates during oxygenic photosynthesis and principal electron donor is H2O. Although no structural data is presently available, a huge body of literature exits that describes function using a variety of biochemical and biophysical techniques. [Energy metabolism, Electron transport, Energy metabolism, Photosynthesis].	0
NC_019693.1|WP_015151612.1|7027880_7028993_-|chorismate-synthase	gnl|CDD|215402	PLN02754, PLN02754, chorismate synthase.	0
NC_019693.1|WP_044196058.1|7022798_7023584_+|D-alanyl-D-alanine-carboxypeptidase-family-protein	gnl|CDD|367124	pfam02557, VanY, D-alanyl-D-alanine carboxypeptidase.	2.2599e-58
NC_019693.1|WP_015151615.1|7036072_7036870_-|3',5'-cyclic-AMP-phosphodiesterase	gnl|CDD|182997	PRK11148, PRK11148, cyclic 3',5'-adenosine monophosphate phosphodiesterase; Provisional.	3.83364e-88

Protein sequences

>NC_019693.1|WP_015151616.1|7037195_7038098_-|hypothetical-protein
MPNPTHRSSLPVPPPVSSPFTVKGTHRTRESGRISESVPLFQSLNSLFPRGVADCSLKCSIGLIYLALHLTLNWGGIPVASARPLLAQVDDSPLDSEPLNSQSVDLSPEIIEGSPVLQRWLQEVPNVLEEIRNDPSFRTRVRVGYAQVTSSDDGSGVNVGVEDLFIGGTGLTVSGDYFAGSGGFSGGGAQLRYYVLPLGGYFNLAPVVGYRHVEGESYSTSGVELGGRAMLVLSRTGGADLSLGYSVVGIGGDQTVGLGTFAVGYAITPEFRLSTDIRRHDADGDNDTRFGIGLEWMPRF
>NC_019693.1|WP_015151615.1|7036072_7036870_-|3',5'-cyclic-AMP-phosphodiesterase
MIPASPLRLAQITDLHLFARPDRKLLGVPTLSSFEAVLRGLLSLNYARDLLLLTGDLSQDETPESYQVLRDLIRPLQIPTYWVPGNHDNLSVMESVLTESPFCADKSFEMGNWRFILLNSQIPGADRGRLSRTSLEWLDWQLYLAGNQATLIALHHPPFPVNSEWLDQINLENAEAFFGILDRYRNVKVVACGHAHQNLLFYRENIAYFATPSTCIQFMPKSIEFALDDAAPGFRLFNLYPNGTWETKVERVPIAAQPDLTALGY
>NC_019693.1|WP_015151614.1|7034691_7035654_+|7,8-didemethyl-8-hydroxy-5-deazariboflavin-synthase-subunit-CofG
MLTAFASCRITYSPAYTLVPTYECFNRCSYCNFRQDPGKSPWLELPDAERILKSLMGTGIREILILSGEVHPNSEKRTDWCDRLYELCELALGLGFLPHTNAGPLSFEEMARLKTVNVSMGLMVEQVTPTLLETVHRHAPSKVPGVRLQQLAWAGELKIPFTTGLLLGIGETPGDRQATLEAIGQIHQRWGHIQEVIIQPYRPGTHQSGEAPGLELKELPAEVARARAILPEAVALQVPPNLIEEPEILLACLEAGCRDLGGIGPTDEVNPDYPHLQVDRLKRILEPAGWELVERSPVYPQYHAGLSPRLRSHLIQAGYY
>NC_019693.1|WP_015149763.1|7033460_7034543_-|photosystem-II-q(b)-protein
MTTTLQQRESANLWDRFCEWVASTENRLYIGWFGVLMIPTLLSATVCYIIAFIAAPPVDIDGIREPVAGSLLYGNNIISGAVVPSSNAIGLHFYPIWEAASLDEWLYNGGPYQLVIFHFLIGIFCYMGREWELSYRLGMRPWICVAYSAPVAAASAVFLIYPIGQGSFSDGMPLGISGTFNFMLVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLVRETSETESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGVSTMAFNLNGFNFNQSIIDSTGRVVNTWADVINRANLGMEVMHERNAHNFPLDLAAGEATPVALTAPSING
>NC_019693.1|WP_015151613.1|7029281_7033064_-|PAS-domain-S-box-protein
MSRIFDEIQEGIVFINAGGDRLDYLNRAAAQLFGGTVAGFENQPEFWREGIEPQWRSQVVHALVRVWETETVEVNYCIVGIDGQRRDLHSKFWAIADDEGTPVRIEGTIKERPPSQELEMAIAQWFNLSLDLLCIAGTDGYFKQLNPMWETTLGYSTEELLSLSFLELVHSEDVASTLAEVQKLSEGKNSIYFENRYRCRDGSYKWMGWTASSPGGDLIYAVARDITDRQQMAAEQARLLTSVQESETRYRSVLSAMSEGVVMQDAKGVIYTCNQSAERILGLSADQMMGLTSVDPRWRAVRTDGSPFPGEEHPLSVTLRTGESFRDQIMGIHKPDGSLTWMLLNTTPLFRPHETQLYGGVATFTDISDRISAEALLRESEAKFRAAFEQAAVGIAHVGLGGNWIEVNQKFCDILGYSREELFTLTYQQITYTDDASFDVEAEDQLYDPAINTVTLEKRYIHKTGSLVWVNMTASMIRNSVGDPQYFLAVFEDISDRKQVELSLKQSQRLLEEAQQIAHVGNWEFDVATEKITWSKELFRIYDYDPEQEGPSLSQLLQKVHPQDAEALKTRIEKAITLGIPYELEHRIVHQNGSLRYVQGKGKVDQNSQGEVVRLFGTVLDITSRHKIEQELQEREQFLRAIWEGVDYSIFVLEVLEGGEFRFAGINPKMAQTAQVPVEKMLGKTLAEALPPEMADLWRPRYVQCVQLRTTLSFEESFVADGIEKWWLMTLSPLQDSSDRIDRIIATTIDISDRKQTELALQHSEAQYRELAQREALLNRIATQIRNSLELDTILDSVVQEIQQVMEIDRCHFAWYRNNGNQEVWEVVTEARNPGLINLIGCYSVEQVGPMINLLLTRETLKFDDINGVSDSIFQEFLSNLGYRAMLAMPMQTEFGRIGVISCACHNRIRVWKPEDVELLAAVCDQLVIALNQAQLYTQARRSAQIAEAKSQELQQTLQELQRTQSQLIQTEKMSSLGQLVAGVAHEINNPVNFIYGNLSHADDYMQDLLNLVEVYRQNYPYPTEEVEEEIEKIDLDYLVEDFPQILASMKLGANRIRDIVKSLRTFSRLDESDMKAVDLHENIDSTLMILQNRLKGKSDRPSIQVIKEYGPIPEITCYVGQINQVFMNILGNAIDAVEMKGEDWVKKGTDDDPVQPTMQLPDPLIRITTTLIEGNRVKIAIADNGIGMKPEAISKIFDPFYTTKPIGKGTGLGLAISYEIIVEKHRGTMHCISEVGKGTEFIIQIPLEQNLHLENPSAE
>NC_019693.1|WP_015151612.1|7027880_7028993_-|chorismate-synthase
MGNTFGHLFRVTTFGESHGGGVGVVIDGCPPQLEISEAEIQVELDRRRPGQSKITTPRKELDTCEIVSGVFEGKTLGTPISILVRNKDVRSQDYNEMTDTYRPSHADATYDAKYGIRNWQGGGRSSARETIGRVAAGAIAKKILHQVAGVEIVGYVKRIKDLEGIIDPNQVTLDQVESNIVRCPDSECADRMIELIERIGREGDSTGGVVECVARQVPKGLGMPVFDKLEADLAKGVMSLPASKGFEIGSGFAGTLMTGSEHNDEFYTDEQGEIRTRTNRSGGIQGGISNGENIIIRVAFKPTATIRKEQRTVNSLGEETILAAKGRHDPCVLPRAVPMVEAMMALVLCDHLLRHQGQTGTFRPKLGQAG
>NC_019693.1|WP_015151611.1|7026867_7027740_-|MBL-fold-metallo-hydrolase
METNPSSEFVVQFWGVRGSIPTPGKDTVRYGGNTSCVEMRIGGKRLIFDAGTGLQVLGQTLRKEMPIEAYMFFTHYHWDHIQGFPFFTPAFIRGNSLHIHGSVPLDAESMEQHFVERILHPNSPVPLEGMQANLKFSEMVCGEPFHVDDIYFETGPLNHPNSAMGYRVTYKDHTVFYCTDTEHFPDRMDETVLHMARNADLLIYDAMYSDDEYNNPKSPKHGWGHSTWQEAVKVAKAAGVKKLVIFHHDPSHNDAFLDKLDGEVKEAFPNSVLAREGLVLDVCESVLAAV
>NC_019693.1|WP_015151610.1|7024458_7026423_-|M48-family-metalloprotease
MKLLWNSWLVTLSLVLPIATPALAEFPVPSPSRLAQTNTETRSTLPTSESTPETASEEPPLAEEDPEPPTAETADEAEDLPQEEEDPESPNPEISDEAEDLPQEEEDPESPNPEPSDEAEETSEAESTLDPEQAAKQAERRHHLERLAEADRLFVAGEIAAAEAIYQEVKPPFSANGKQAAISTLPEPLSDPEQLSPASRVYWREAQAGWENQLESRIFVPLEFLVEASPEFLPGHLLLAEAHTTYEQPEKAVEVLERATTFYPNNPELLRVKIAALAATEQWLEASIAARQFAILNPDHPDAEEFATLAEDNFGKFRGYIRKMIAGNAIGNVVTGAIGVALTGNPLGALSAVETLVMLARGESAIGRSIANQAVEQLDMVEDEEIVAYVQELGERLSKLSGRDDFEYEFYVIKDKNLNAFALPGGKIFVNAGAILHSDTEAELAGLITHELAHAVLSHGFQMVTHGNLIGNMARYVPFGGTLANLLVLDYSRDMEQQADVLGTRLLTSAGYSADGLRNLMVKLKEQYGEGSSFWKFMSTHPPTKERISDLETLIERGGYNRFAYEGVERHQEMRQRVAELLREELSEEDLVKLDIQLEEVEIEETEEENLESDEDEDEDEVNPEGEELDSDEDEVNPEGEELDSEDEEELEEE
>NC_019693.1|WP_015151609.1|7023647_7024340_+|hypothetical-protein
MSQTALNLVAISVFLMTLSVLLGPILEISPLIGAIATASLLGFFTLDTLGWQGKGANLIVDVFAGMSPDHRSRVLRHEAGHFLVAYLLEIPITGYALNAWEAFKQGQSAGGGVQFDDQELLAELQQGSLSAQLFDRYCIVWMAGIAAETLTYERAEGGAEDRTKLKAILAQNRKSATDAQLKERWAILQAKTLIESNLDAYQSLVTAMEQRLAVSECYQILGSRIPIKAE
>NC_019693.1|WP_044196058.1|7022798_7023584_+|D-alanyl-D-alanine-carboxypeptidase-family-protein
MGEDIPQAVRDTSENVSTVQGSKSVKWIVIAVIAGTVALIAGVLVAWQGGMLGLLNNSEVAQTEQTEAPDSNATEDPNAPTTETLLGHFPYKEASTEDLQPISSDGRILMRQAAARAFLDMKEAARSQGVYLVPISGFRTEEDQKYLFFEVKAQRGQVAMERAEVSAPPGYSEHHTGYAVDIGDANLPATDLSPNFENTPAFQWMEENAAYYSFELSFPKGNTQGVSYEPWHWRFVGDRDSLETFYKARTQEVQEVEETQP
>NC_019693.1|WP_083896831.1|7044798_7046103_+|sigma-70-family-RNA-polymerase-sigma-factor
MDQRFTALERIGLNSLSIHSIGESIVVQSTTADIQILTEEEQLLKRLAAGEDQAFWSLFQQHRDHLFRCCLKWMNGNSTEAEDLLSQAMLKAWKKAHKYAEKIENFKSWITKLIRNYWLDLKRIRGLNTVEYIECYGHQEELKWVSVQDSPASALENDEQKSVIRSAINQLPIRVRETFILHFYQEFSHQEIAQKLEISYPNVCKRISQARAILREELRGYFIEEENLLIKSVVTPVETELVTEEISQKNVEEVDTLVDQRLTSSVGVTIAETVVSEEAIEVEQFQPPSESVAIAATSHRTLSIIKTADSCVKSPLSESLLASILAWVQLPEKPKNWGRFWLPVRWIRERYQVRQWVEKWMVKTESPPGTGVASCQPRIKSLSPKNMRGNFSLSLTSLKGANFLDNINSDPRLYGISLRLKKEDKPPDFCLCFL
>NC_019693.1|WP_156824118.1|7048515_7049733_+|hypothetical-protein
MAMFCLNMLKISSELAKQDKDLAKTYEKLRQKYQELVKEDADQELIATYQTLVKKTGRSNYEDMASKYFQHFLLIADAMNKVGGNDIDIWNDEDKFYYDILKAPGSNVSGANSNGALSMKVRSLVGLIPLFAVETIDKDIVKDYLNLDFQARMNWFVKNRPQLLNHQNIELRSSENQDETDPEKGLYLSLVNKERLQHILSKMLDSTEFLSDYGIRGLSKYHKDHPYVLWVQGKEQRLEYEPAESKIPMFGGNSNWRGPIWMPVNFLLIESLQKFHAYWGDDIKVKCPTATGEIKEMNLEEVSIELSKRITSIFLKKSGSNPSEDTTSESSSESSSSKPSSTEPWRPVYGGSEKFQKDPYWRDLILFYEYFHGDNGAGIGASHQTGWTGVVANLIQDLAEKSAFK
>NC_019693.1|WP_015151619.1|7049875_7051693_+|GMC-family-oxidoreductase
MSPLHEFVISVDVETVSKTSYDVVIVGSGIAGAIVAKELSEQGKSVLILEAGQSKDLTLAGFQSYIDTFYSAAEKNSNAPYAKNPNALSPTDDDEYFVEKGPMRLSGSYTRVPGGTTMHWEGKTIRMLPEDFELRTKYGQGLDWPISYHDLMPYYNKAEYEIGVSGNKEEQEALGVPFDEGYVFPMEAMPPSYLDKKVMDKVKGTKVKLDEEEYELTFAGFPQGRNGVPNPKYDRGNPFVPEGVSSIHPVQYGERCQGNANCVPLCPAQAKYDARRTLTKAFQTGRVHLLCQAVAFKIEIEPENGRVTAVHYKRYEEPKNPAHKVGIAKGKLFVLATNAVENARLMLASDLPNENGLIGRYLMDHPFTLAWALMPEVTGTMRGPLATTGIATFRKGGFRQKQSAFAADIHNDGWGWATGSPYSEVTDAIDNKNKYGQELRDTLVNRISRQLLLAFMCELPPEPSNRVTIDAKYKDQLDNFRPVINFNIPDYSIRTLAYTRKLSRVIFQRLGAEDYTHYNPKDPAYFEFEGEGYFYKGGNHFSGTHIMGTNDKNSVVNSKLRSWAHENLFLVGSGSMPTIGSSNTSLTIAALSFMASEQMLKDLNA
>NC_019693.1|WP_015151620.1|7051756_7052851_+|hypothetical-protein
MSKNDKLKLITTVKELRHYLKKALVLEHATIPPYITALYSMHPGKNLESFHIIRAVAVEEMLHLTLIANLYNAVGGDMKKTLTHPEFIQTYPTYLPTGAIDFKVGLNKFSPEAIDTFMKIERAEEVEDDKPLVVSRPVQEQYNFLTILDGKPSDTFYSIGLFYAEIIRGLYALHKEMGDALFCGDPSRQITPEYYYNGGGDIIPVTDLRSAIRAIKLIQEQGEGARSGTIYDAERELGHYYRFQQIKLGQYYVVDKDDPENSDRPDHPTGAKFTVDWDAVYPMKSNPHLSDYPEKSEIYTAAKEFYAHYRKFLGDLEKAFDGNPKELIPAVGGMFKLKESATALIRNPIPGMPGVNAAPIFRLD
>NC_019693.1|WP_015151621.1|7053047_7053551_+|hypothetical-protein
MDINSPELTEYFYDLSVTLTGFSRFHLQGTGQGELYFKTIHEVIGPNILIDLLKLFHEIDEAAKKSDDNLIRTNRLRLEILGSEQLGPIARNIIKLWYVATWYELPKDWREMYGTKTQDRTFIPSSTAYPEGLLWPAIGVNPPGAKSPGYATWSEEPLVGLPKSKKS
>NC_019693.1|WP_015151622.1|7053629_7054298_+|pentapeptide-repeat-containing-protein
MNIATSFRQLSTLTLSIFVSLTLWIAPAHAFVGTDYNQLMLKNACVNCELSGVDLSGKDLYGSALNGANLSNANLSGALLKDAKLQTANLSGANLSNAEMSGITLSEANLTGANLSNAELENALMSKVDLTGADLTGADLIDAIISDANLSNASVTQAQLKKAILSRSNLSGADFSSSSMRDTKLADANLTSTNFHEADLFKSLMPDKTIYNGDVSRFGAVQ
>NC_019693.1|WP_156823989.1|7054560_7055568_+|myo-inosose-2-dehydratase
MSITPPATAATARDNESVLISLVTPSSGAILNPTFDRNKIKLGITPTGWSNSDDRTIDLDPPIPFQQILSETALAGFKGSQMSPKYPQDLKELKRELGMRNLTISEPWVGTLFTVGKAQETFEEFDKQVAFMKEMNGNSIVVAELGGAVHQKPGADPLVDRPKFTDQQWSDLTEGLNQLGAIAQQNGMQLVYHPHIGTGVENFEDIDRLMSNTDSNTVKLLLDTGHLYYAGVDPLAVTKKYVNRIKHVHLKNIRQPILNESKKTGRGFLDSIRAGIFTVPGDSAGTVNFQPILQELAKANYEGWLMVEAEQDPNNAEPLQYALMARTYLRDQIGF
>NC_019693.1|WP_015151624.1|7055694_7056078_+|DUF4440-domain-containing-protein
MSLRDREEIRRIFEEVYPSNVRSVDLMSYGEMYTEDAQWMPPDAPGCRGIQDILEGFAIQCAHQAIDPTFIAEEIEVMGDFGYVIGTSESTIHPKDGSPTHVVKYRALWLMRKERNSWKISRQIWNK
>NC_019693.1|WP_015151625.1|7056239_7057247_+|sugar-phosphate-isomerase/epimerase
MSSNGLIPQDVYLSFFMFTTNLKPHDHESRKRVLKHIKELTQIGYTGFEFPIAPSDNTDYSQEIQDYANLRRFLDDEGFRDVAITTNVGATPSCDPSSFDAEQRKQALQYLKARVDITAALRGEVMMGPIIVPYGAFLQDGNTPIWSDRLQDALARRYANAQPALQELGNYAEDKNVKLAIEPITHWETPGPNKLSQVLEFLEGVSNPQVGVVIDTAHEILDGEGPEIFAAQVSQLANDRRLHYVQVSAPDRGAVHTSWIPWESLFKPILAVYNGPVAIEVFNAIPEFVDSLRLSRRKFWIPGEDPENQYPSAYDIAQEAIKITRKKLTHIYNLD
>NC_019693.1|WP_015151626.1|7057494_7059450_+|DUF1929-domain-containing-protein
MRLNNITNRTTIISVFFIFILTLAITFCGWKQAIASPLVGAKEEMGAWETIPMAPKESLMQSVHTILLPNGKVLSVNGSSFRNTLLNAQGKTTFVEGVGSGDYDSINNTSLFDPQTQKFERISSPPAMQDGQSNDLFCGGHLQLADGNLLFISGTGRYYPGGRFTGSKQANLYNWQTGEWSPAGQMKEGRWYPTLVELADGKIVIFSGLKLNAPNQINPSIEIYDPNTQKFHYIDLTTVDNSPFNTYLKGADDYDSIDLYPRVFPTADGKLLITGDEAGIANVLVQNKSKTSYLMSVHEDASGKFSVSFEVGPERFETTKAYGTALQVPNSEDVLLLAGMIGTNDINFGRGGNTANYAGAKIASSLQRWVSPEHSGEKNGKWETVEKFLDKPRANLEAVILPSQEILVVNGGEYPEYTPIYEPLLMTPNSDAPGGYHIKPMNPAKLPRLYHNGAILLPDARVLSIGGNANRAAVEKDGTIHVDIGRDPQNNFILAKLTDKSAQAKEFSLQEYYKSPQSYFAPGDPEPFVPAEMWQAEVFSPPYLFKPGARPEIVTVPNSIQYGKTNQISVKDATENGSLVLVKLGAETHSLDFGQRLVELPIKNIALGNESTLDFQAPTNPNLYPPGYYMMFYLNDIGKPSHAQMVKLEHS

Crispr_ID: NC_019693_76

• CRISPR_ID: NC_019693_76
• CRISPR_location: 7196696-7196792
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_76

Consensus_repeat	Method
ACAAGAAATAACGATTTTTCGTCATTAAATTT	CRISPRCasFinder

spacers of NC_019693_76

>76.1|7196728|33|NC_019693|CRISPRCasFinder
ACACCCAATTTAGGGCTTCGAGCATTTACTCCG

CRISPR arrays and Neighbor proteins around NC_019693_76

CRISPR arrays

The CRISPR arrays of NC_019693_76

>merge|NC_019693|76|7196696-7196792|CRISPRCasFinder
ACAAGAAATAACGATTTTTCGTCATTAAATTTACACCCAATTTAGGGCTTCGAGCATTTACTCCGACAAGAAATAACGATTTTTCGTCATTAAATTT

>NC_019693|76|74|7196696-7196792|CRISPRCasFinder
ACAAGAAATAACGATTTTTCGTCATTAAATTT	ACACCCAATTTAGGGCTTCGAGCATTTACTCCG
ACAAGAAATAACGATTTTTCGTCATTAAATTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015151703.1|7184141_7185251_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379114
NC_019693.1|WP_044196079.1|7193376_7193556_-|hypothetical-protein	unknown	unknown	gnl|CDD|366364
NC_019693.1|WP_015151708.1|7193775_7194849_-|DUF3616-domain-containing-protein	unknown	unknown	gnl|CDD|372008
NC_019693.1|WP_015151716.1|7201693_7202923_-|methionine-gamma-lyase-family-protein	unknown	unknown	gnl|CDD|311036
NC_019693.1|WP_044196082.1|7204160_7205429_-|glutamate-5-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|143398
NC_019693.1|WP_015151704.1|7185421_7185616_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151715.1|7201422_7201602_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151701.1|7180573_7181641_+|chlorophyll-synthase-ChlG	unknown	unknown	gnl|CDD|215028
NC_019693.1|WP_015151706.1|7187407_7187899_-|PspA/IM30-family-protein	unknown	unknown	gnl|CDD|224755
NC_019693.1|WP_015151710.1|7195402_7196608_+|coenzyme-F420-reducing-hydrogenase-subunit-beta	unknown	unknown	gnl|CDD|223966
NC_019693.1|WP_015151719.1|7205438_7205846_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151705.1|7185680_7187051_-|16S-rRNA-(cytosine(967)-C(5))-methyltransferase	unknown	unknown	gnl|CDD|237856
NC_019693.1|WP_015151702.1|7181778_7184055_+|penicillin-binding-protein-1A	unknown	unknown	gnl|CDD|273955
NC_019693.1|WP_015151717.1|7203167_7204037_+|acyl-CoA-desaturase	unknown	unknown	gnl|CDD|224316
NC_019693.1|WP_015151707.1|7188048_7193133_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|236848
NC_019693.1|WP_015151711.1|7197368_7198223_+|low-complexity-protein	unknown	unknown	gnl|CDD|224276
NC_019693.1|WP_015151714.1|7200206_7201160_+|succinylglutamate-desuccinylase/aspartoacylase-family-protein	unknown	unknown	gnl|CDD|349469
NC_019693.1|WP_015151720.1|7206371_7206974_-|6,7-dimethyl-8-ribityllumazine-synthase	unknown	unknown	gnl|CDD|234606
NC_019693.1|WP_015151712.1|7198235_7198676_+|hypothetical-protein	unknown	unknown	gnl|CDD|226553
NC_019693.1|WP_015151713.1|7199157_7200063_+|30S-ribosomal-protein-S6--L-glutamate-ligase	unknown	unknown	gnl|CDD|182468

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015151703.1|7184141_7185251_+|AAA-family-ATPase	gnl|CDD|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	3.40463e-17
NC_019693.1|WP_044196079.1|7193376_7193556_-|hypothetical-protein	gnl|CDD|366364	pfam00909, Ammonium_transp, Ammonium Transporter Family.	2.36535e-09
NC_019693.1|WP_015151708.1|7193775_7194849_-|DUF3616-domain-containing-protein	gnl|CDD|372008	pfam12275, DUF3616, Protein of unknown function (DUF3616). This family of proteins is found in bacteria. Proteins in this family are typically between 335 and 392 amino acids in length. There is a conserved GLRGPV sequence motif.	0
NC_019693.1|WP_015151716.1|7201693_7202923_-|methionine-gamma-lyase-family-protein	gnl|CDD|311036	pfam06838, Met_gamma_lyase, Methionine gamma-lyase. This is a putative pyridoxal 5'-phosphate-dependent methionine gamma-lyase enzyme involved in methionine catabolism.	0
NC_019693.1|WP_044196082.1|7204160_7205429_-|glutamate-5-semialdehyde-dehydrogenase	gnl|CDD|143398	cd07079, ALDH_F18-19_ProA-GPR, Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19. Gamma-glutamyl phosphate reductase (GPR), a L-proline biosynthetic pathway (PBP) enzyme that catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The glutamate route of the PBP involves two enzymatic steps catalyzed by gamma-glutamyl kinase (GK, EC 2.7.2.11) and GPR (EC 1.2.1.41). These enzymes are fused into the bifunctional enzyme, ProA or delta(1)-pyrroline-5-carboxylate synthetase (P5CS) in plants and animals, whereas they are separate enzymes in bacteria and yeast. In humans, the P5CS (ALDH18A1), an inner mitochondrial membrane enzyme, is essential to the de novo synthesis of the amino acids proline and arginine. Tomato (Lycopersicon esculentum) has both the prokaryotic-like polycistronic operons encoding GK and GPR (PRO1, ALDH19) and the full-length, bifunctional P5CS (PRO2, ALDH18B1).	1.09561e-180
NC_019693.1|WP_015151713.1|7199157_7200063_+|30S-ribosomal-protein-S6--L-glutamate-ligase	gnl|CDD|182468	PRK10446, PRK10446, 30S ribosomal protein S6--L-glutamate ligase.	6.65363e-147
NC_019693.1|WP_015151701.1|7180573_7181641_+|chlorophyll-synthase-ChlG	gnl|CDD|215028	PLN00012, PLN00012, chlorophyll synthetase; Provisional.	0
NC_019693.1|WP_015151706.1|7187407_7187899_-|PspA/IM30-family-protein	gnl|CDD|224755	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms].	3.45019e-12
NC_019693.1|WP_015151710.1|7195402_7196608_+|coenzyme-F420-reducing-hydrogenase-subunit-beta	gnl|CDD|223966	COG1035, FrhB, Coenzyme F420-reducing hydrogenase, beta subunit [Energy production and conversion].	3.65643e-97
NC_019693.1|WP_015151705.1|7185680_7187051_-|16S-rRNA-(cytosine(967)-C(5))-methyltransferase	gnl|CDD|237856	PRK14901, PRK14901, 16S rRNA methyltransferase B; Provisional.	0
NC_019693.1|WP_015151702.1|7181778_7184055_+|penicillin-binding-protein-1A	gnl|CDD|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NC_019693.1|WP_015151717.1|7203167_7204037_+|acyl-CoA-desaturase	gnl|CDD|224316	COG1398, OLE1, Fatty-acid desaturase [Lipid metabolism].	3.05887e-107
NC_019693.1|WP_015151707.1|7188048_7193133_-|PAS-domain-S-box-protein	gnl|CDD|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	3.71689e-153
NC_019693.1|WP_015151711.1|7197368_7198223_+|low-complexity-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	6.72594e-34
NC_019693.1|WP_015151714.1|7200206_7201160_+|succinylglutamate-desuccinylase/aspartoacylase-family-protein	gnl|CDD|349469	cd06251, M14_ASTE_ASPA-like, Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like; uncharacterized subgroup. A functionally uncharacterized subgroup of the Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA) subfamily which is part of the M14 family of metallocarboxypeptidases. ASTE catalyzes the fifth and last step in arginine catabolism by the arginine succinyltransferase pathway, and aspartoacylase (ASPA, also known as aminoacylase 2, and ACY-2; EC:3.5.1.15) cleaves N-acetyl L-aspartic acid (NAA) into aspartate and acetate. NAA is abundant in the brain, and hydrolysis of NAA by ASPA may help maintain white matter. ASPA is an NAA scavenger in other tissues. Mutations in the gene encoding ASPA cause Canavan disease (CD), a fatal progressive neurodegenerative disorder involving dysmyelination and spongiform degeneration of white matter in children. This enzyme binds zinc which is necessary for activity. Measurement of elevated NAA levels in urine is used in the diagnosis of CD.	5.46762e-97
NC_019693.1|WP_015151720.1|7206371_7206974_-|6,7-dimethyl-8-ribityllumazine-synthase	gnl|CDD|234606	PRK00061, ribH, 6,7-dimethyl-8-ribityllumazine synthase; Provisional.	5.67108e-80
NC_019693.1|WP_015151712.1|7198235_7198676_+|hypothetical-protein	gnl|CDD|226553	COG4067, COG4067, Uncharacterized protein conserved in archaea [Posttranslational modification, protein turnover, chaperones].	1.53033e-38

Protein sequences

>NC_019693.1|WP_015151710.1|7195402_7196608_+|coenzyme-F420-reducing-hydrogenase-subunit-beta
MTAVQPSPKHQKSKALKPGSRPPAKELCSECGLCDTYYIHYVKEACAFLNQQIATLEESAHGLSRNLENPDELYFGVHQHMMAARKQEPIAGAQWTGIVSTIACSMLDRGLVEGVVCVQNTPEDRFGPMPILARTKAEVLAAKVNKPTLSPNLSVLEQVEQSGMKRLLVIGVGCQIQALRSVQKELGLEKLYVLGTPCVDNVSREGLQKFLETTSKSPETVVHYEFMQDFRIHFKHEDGSIEKVPFFGLNTKELKDVFAPSCLSCFDYVNSLADLVVGYMGAPYGWQWIVVRNQTGQEMLDLVTEQLETQPVMSRGDRHAAVQQSIPAYEKGVTLPMWAAKLMGVAIERIGPKGLEYARFSIDSHFTRNYLYVKRNHPEKLEAHVPEFAKQIVSQYQLPES
>NC_019693.1|WP_015151708.1|7193775_7194849_-|DUF3616-domain-containing-protein
MSPAFLLSRLLLKFDPETEERVGDLSAVTFTPDGSLWVGSDELLTLERLSLIEPYVYGNHQPFEIGEFIELFNNEDEIDIEGMDYCEGYLWFTGSHSTKRNKPKGKNTEKDINRLAEIKTDANRYLLARIPIQQGIPVQACPDPLNSDRPLTAASLQKTESGNILIDALKKDVHFGSIIDAQFPSKENGLDIEGLAVRGSKILMGFRGPVLRGWAVIIELEVEESEPGILTLKAIGPEGRLYKKHFVDLSGLGIRELCLEGEDLIVLAGPTLDLDGGMKMFRLTGVFERQGDTLIAQDETELKVLFDLPFKLGTDRGEGLALLPCLGQPNSLLVVYDSPDPARLVNSDAVFGDVFRL
>NC_019693.1|WP_044196079.1|7193376_7193556_-|hypothetical-protein
MPAGFICLESGFPRSKNSINVAVNNFTDFGCSVALFWAFGFALHRPEPFQVGKPQLLRI
>NC_019693.1|WP_015151707.1|7188048_7193133_-|PAS-domain-S-box-protein
MEFLKQILAFEPDIFYGYAYLWNLNGIKLHVAEALASPAMLAALAVAEGLIFLIFLYLIRTDRPLPDPRFPKHQPPRFREIFNSSFQFMAVLNPEGMILDVNQTALEWGELQLEQVFGVSFWQTPWWSGNQPSQDRLIEAIATAASGKSRRYETVIGGSGCPLRTLDFSIRPMLGQGGQVTQLIAEGRDITARKGYESELLRIRKAVDSAGDAIAISDLRGHRIYQNFACTQLFGYTRDEMNAAGGPWMLYQDPVVSQQAFETVSSGGSWQGEAEMKSKGGDCLQIAVRADAIVDERNQIVGFIGIYTDITARRQLEAELRHQETDYRQLMEQASEGIFIIDERGNYLNVNPRACEMLGYSREELLQLNFKAIAYQPEIEIFSSPLDGLRLGENCRSEHWLRRKNNTLLPVELSAKMLPDGRMQAIVLDITDRKRSEAALRKYQEQLENLVAQRTAELTRANRQLQSEIVARQKAQAELEQFFKVSADLMAIASFEGYFKRVNPAITDILGYSPDEFSRQFSLDWVHPEDRELSEEKTQQMLASKEAIAFENRYRTRDGSYKWISWSAVPVPEEQSIYCVGRDISDRKSVENALHQETRRVTELQNRFQRLADNLPGVIYQYLITTDGTISFPYISSGCRDILELEPEEIEQNAQLMCSLIHPEDSQNFNESIARSAQILQPWKRKFRVITPTGKIKWLQGESRPEPQPNGDILWDGVAIDITDLKQLEQELLHSEERFRTSVENMLDCFGIYSACRNERGEIIDFRREYVNASARQQYHCSRDEMDHDCSFCQVMPDQRQSILFSKYAQVVQTGQPLNEELILYETEGNLGLNGMKNRPPVREAFDIRATKLGDGFAVVWRDISDRKQMETAIERERQQLQQIVNCAPVAIAMFDTQMCYLAHSSQWLTYHGLDSFGRSKTSDNNNGTQPSLIGRNYYQVSSDIPERWRQAHQRALQGEIVSVTEDLWQKLDGSSTYIRWTISPWYLAEGEIGGIAIAIDCIDELVKAREAALESARFKSQFLANMSHEIRTPMNGVLGMAGLLLETPLSTQQYDYAKTIRASAQHLLSIINDILDFSKLEAGEMHLEQFDFNLYESVEQVLDLLGAQAEAKGLDLSFLFDPNLARNLQGDPVRLGQILLNLVGNAIKFTEVGEIIIQASAIAETEETACIRMSVKDTGIGISPEGQNKLFQSFSQVDASTKRQYGGTGLGLAICKQLVEMMGGQIGVDSKLGEGSTFWFTAEFKKQLHFTPIEVSPPRKLPSLRVLVVDDNPRIRQSVRELTEAWGMHTDDAANATEAWNALQQTVTLNKPYDVLLLDLQLPSKEGLQLLENLHYNREQFDSHLFPETQVILMTNQSQRDIAESLLSRGVASYFFKPVRASRLFDTLINVVNGPSSTASSMGTLHAPIIPAYAINILVAEDNLINQTVILSQLEMLGYQPDCVTNGIEALEAITQKTYDLVLMDCQMPVMDGYAATKELRRREEAQRHTIVIALTANAMRGDRQKCLDAGMDDYLSKPIEREDLAAAIRRWIHKKPGPDNCLQVPSPVKIPRIEPTAIPSSLLTLNTASPLPFSPPECPVNMDRLLKVTRGNLSLQQRLLQVFIDKIPEDIEAITQALSNQDLAQMEHCAHRIKSAAGNVGVSSMSAIAAQLESLARQQTLEGTAELASQLPTILEQVQGFFDEHFCQKTSV
>NC_019693.1|WP_015151706.1|7187407_7187899_-|PspA/IM30-family-protein
MALGDRINRLIRSNITDWKHQRKDYQRELEQTLTEFKQSVQNVISSQELLWRDYQNAQQQANELVESAKLALQQQNEPLARELLTRKQSYSKQAEELKQRLDELIPTVTLLEQQLTALESERNLFKASLASANLEQDLEAMPDLDFVEIDAELDLLRSRLNRL
>NC_019693.1|WP_015151705.1|7185680_7187051_-|16S-rRNA-(cytosine(967)-C(5))-methyltransferase
MSNPRQIAFLALRDVHRRGVFADIALDKWLQKAKQQEESALIPSDRRLATELVYGCVRRMRTLDAIIDQLAKKKSANQPDDLRIILHLGLYQLRYLSTIPASAAVNTTVELTKDNKFKGLAGFVNGLLRQYIRLAESENTDPLVLPDDEISRLGLLHSFPDWIVANWCDRLGVAETEKLCTWFNQSPTLDLRINPLKTTLEEVETAFQSAGVQVARLPHLPQALRLCSGAGAIENLPGYQAGWWTIQDSSAQLVGSLLEAKPGQVAIDACAAPGGKTTHLAEMMGDTGTIWACDKAPSRLKKVKENADRLQLQSIQTLSGDSRNFTQFHQTADWVLLDAPCSGLGTLHRRADARWRQTPENIQELSQLQGELLAETANWVKPGGHLVYATCTIHPKENEEVILGFLASHADWEIDPPTTDSPAAHFAQPEGWITVWPHHHDMDGFFMVRLRKQQTE
>NC_019693.1|WP_015151704.1|7185421_7185616_+|hypothetical-protein
MNILMEVSAAAGASANNFPVSFTVVYVVGFIAAVTLGSIAWYNSKRPPGWEDKDRPDVVPKVDK
>NC_019693.1|WP_015151703.1|7184141_7185251_+|AAA-family-ATPase
MLHRLYVNNFRCLENFEFTTKGISSALLIGKNGSGKSTIATALEVLQSIGRGINKVNQLVQDSDFSQGRSNIPIRFEIEVFLQEKLYKYSLAFDFLEQFKEIRVSEEELLVNGRAIYTRKEAKITLLNSSQNREAEFLVDWHLVALPVIQEQSQTDPLHIFKTWLARMIILAPIPSFMKGDSLGETLEPHRTGSNFGEWFSGLLSRYPAAYTQVDHYLRDVIPDFKDVRNELMGKDFKTMIVGFEEKNANLSVYFKDLSDGEKCFFLGAVVVAANQYYGALFCFWDEPANYLSLSEVGHFVTSLRHSFKTGGQLIVTSHNPEAILKFSNENTWLLHRNSHLEPTLIRPLEEISIPGDLVDALIRGDIEG
>NC_019693.1|WP_015151702.1|7181778_7184055_+|penicillin-binding-protein-1A
MAVRGVDVAKFISKLKNISKKFGSASGTKPRKSRDFPPETGGDRPGVDRSNPTVLRGTPLSLAPGEQGKPLEPQAIAPGENPSDPDKPSKPGKPRRNIFSTLKRLWFNPGGKPLYRRRIFWVGLGVVAVSSSAGTLTWVWWRIDRSLPDVSEVFTFVRDGTLTITTEDGTILQQIGPATRDKLRMQDIPEPLVEAFIASEDSRFYKHGGVDYQGVLRASVANILAREVVEGGSTITQQLARMVFLTQEQTAVRKIREAFLARKIEKNMRKQQILERYLNYVYLGSGAYGIADAAWVYFSKSVDELTLSEMAMIAGLPPAPSVYSPLVNPQNARTRRNIVLQRMTELGYITPEEATTAREQTLEVQASSPKRLKVEAPYFTSYIQKELPKLVSKEALEMGGLTVETTIDLEWQKIAEKVVKEAAELDGPAQGFDQAALVAIAPDTGEIKVMVGGRSFEESEFNRVTQAQRQPGSTFKGFVYAAAIAAGWSPYDGYEDANFRVDGYKPRNYGGKYRGWVSIADALTNSINVVAVKVLIDIGFEPTIELAKNMGIKSKLDPIYSLALGGSEVNLLELTSAYGTIAAEGNYHEPHGITRIIDRRGDTIYQGKSQPKQALDKETSAIVTWMLEPVVQYGTGSAAQLSNRPVAGKTGTSDEARDLWFIGYIPQLVTGVWLGNDDSYPTWGSSSTAAFTWRQFMEQIVEGMPVEEFPEIPERLDGRQEFIKTKPVTPNSIFYGDTTPDNAQSGSANAGDYSDGYY
>NC_019693.1|WP_015151701.1|7180573_7181641_+|chlorophyll-synthase-ChlG
MSNPPTSESNLSNSPDRVPPPEAVDSATPIPSASPESSNRNARTRQMLGMKGADVQEKSIWKIRLQLMKPITWIPLIWGVVCGAAASGNYEWKLEHILIAAACMLMSGPLLAGYTQTINDFYDRDLDAINEPYRPIPSGAIAVPQVISQIWVLLLAGIGVAYALDIWAGHDFPTITALAVGGSFVSYIYSAPPLKLKKNGWLGNYALGASYIALPWWAGQALFGEIGPKIMVITLIYSMAGLGIAIVNDFKSVEGDKQLGLQSLPVMFGVGTAAWICVLMIDIFQLGIAGYLISIHQNLYAAILILLVIPQITFQDMYFLRNPLENDVKYQASAQPFLVLGMLVTALAIGHANII
>NC_019693.1|WP_015151711.1|7197368_7198223_+|low-complexity-protein
MNLQKFETLYREGKRDFSQWDLSQEKAAWVNMSYVNLTGANLSHSQFCSAILQGATLVEANLEQTKLRAADLRRADLSHANLMGSDLSRADMIETNLTGANLEQANLTEVIFSEVIFADANLSRANLQGLNLSGINLSGANLQEAHIAEVSFHNANLSRANLSGLDLSETDLSGANLSYADLSDTQLTEAILYGANLTGAILTSAQLDGAKMNGSLVDGADLSQANLQDAEVKWVDLTNANLKNTDCVGASLKLANLSQENLNDANIYQSDLQGAIAPKHNSLE
>NC_019693.1|WP_015151712.1|7198235_7198676_+|hypothetical-protein
MKQKPQLPVIGWREWVSLPELGIEKIKAKIDTGARSSAIHAFDIETFHQDGKHLVCFKVHPYQRDSIQTVATTSPLFDERQVRNSGGHAELRLVILTPIEILGYQWPIELTLTNRDVMGFRMLLGRQALRHRFLVDPGKSFLLHPK
>NC_019693.1|WP_015151713.1|7199157_7200063_+|30S-ribosomal-protein-S6--L-glutamate-ligase
MKIAILSQKASLYSTRRLKEAGEQRGHHMKVIDYLRCYMNIASHRPTVVYQQKQLEDFDAIIPRIGASKTFYGTAVVRQFEMMGVFTANESQAISRSRDKLRCLQLLAREGIGLPVTGFANSTKDIEGLIEIVGGAPLVIKLLEGTQGIGVVLAETTQAAKSVIEAFRGLDANILVQEFIKEAEGADIRCFVVGDKVVASMKRQSEPGEFRSNLHRGGTAEKIKLTPEERSTAVRAAKTMGLKVAGVDILRSNHGPVVIEVNSSPGLEGIEAASNVDVASKIIEFIEKNSAPKKTRDRNQY
>NC_019693.1|WP_015151714.1|7200206_7201160_+|succinylglutamate-desuccinylase/aspartoacylase-family-protein
MSGVIQIGNATIPPGEQRRLELPVARLPTQTMLGLPVTVINGTRPGPRLWLSAAIHGDEINGVEIIRQVLHQISPRQLCGSIIAVPIVNVFGFIEQSRYLPDRRDLNRSFPGSARGSLASRLAHLFMKEVVMRSTHGIDLHTASHHRINLPQIRANLGDRETYRCAQAFGAPLMIHATTRDGSLRQAATQLGIPVLLYESGEALRFDAEAIAFGTRGIMQVMAMLGMISAVAPSPFPPSLEVKKTQWVRSPSSGILHLEVGLGQSISKKQRLGIICDAFGDQRMKLYAPFDGVIIGHTQNPLVNQGDAILNLAAIEP
>NC_019693.1|WP_015151715.1|7201422_7201602_+|hypothetical-protein
MKIQTGDCLISRDGRYYRVIDCSGEFISLMPLQGYTVFTCRQSYLESSFGFVETQQQVA
>NC_019693.1|WP_015151716.1|7201693_7202923_-|methionine-gamma-lyase-family-protein
MDRSQWLQEAETALFPLFCQIDAQVKQNLARVLGAYRRHRVGVHHFAGVTGYGHDDLGRQTLDQIFAEVMGAQAATVRVQFVSGTHAIACALFGVLRPGDEMLAVAGAPYDTLEEVIGLRGTGQGSLMEFGVSYRQLELTPTGEIDWVALQTAITNKTRLVSIQRSCGYSWRPSLSIADIEKIIHLVKAQNPETICFVDNCYGEFIEDREPPAVGADLIAGSLIKNPGGTIVEGGGYVAGRADLVEAATCRLTAPGIGSSGGATFDRNRLLFQGLFLAPQMVGEAMKGNHLTAYVFDRLGYPVNPAPTAPRRDVIQGIQLGSPEKLIAFCRAIQKYSPIGSYLDPVPAPMPGYESELVMAGGSFIDGSTSELSADGPLREPYVVFCQGGTHWTHVAIALEAAVAAVGPA
>NC_019693.1|WP_015151717.1|7203167_7204037_+|acyl-CoA-desaturase
MTIVSSTQETQETIGQDLSQMRPDWPVIIFMIAIHALALFAFLPSTFSWAAVGLAVLFHWVTGGLGVTLGFHRLVTHRSFTAPKWLEYFLVLCGTLSCQGSPIDWVGLHRAHHLHSDNSADPHDSNQGFWWSHMGWLFYHSPAEAEIPRLTKDIADDPFYQFCDKFLLPIQIALGISFYFLGEAISPGLGWSFVVWGIFVRLVVVFHCTWFVNSATHKFGYRTYDSEDRSTNCWWVALVTYGEGWHNNHHAYQYSARHGMQWWEIDFTWMTIQILQALGLAKNVKLVGK
>NC_019693.1|WP_044196082.1|7204160_7205429_-|glutamate-5-semialdehyde-dehydrogenase
MTTDSTFPPNPDAMAVVESVYQASLIMAQTSSQQRTRALEEMAKSLKQASDDILEANTLDLEASREMAVPDLILEWLKLTPERIQTTVQILQRLAELSDPMRRVMNASYQVEGSQSYCQLMPLGVISLVYEALPDLGAIAAGLCIKTGNCLILKGGMYGAHTNAAIADALQRALLKVEMPESCLEMIPAEMGVSTRDLVRQDKYINLVIPYGRPSLVQQVIRQATVPVLKSGMGNCYLYWSPSGSMDLARWVIQDSHQSEPDPVNAIEKVLIHRNQKPSSLTMLFNSLQDKGFEVRVDDLLSEEFSELKKVEESEWSSAYLTKTVAFKVVDNLEAAIAWINQYSSGHADCIVTESYLESSQFGGGVNSASTYINASPRFYRYPKQGDAIFLGMSNQKGHRRGLIGLESLTTVKHIIQGKGQV
>NC_019693.1|WP_015151719.1|7205438_7205846_-|hypothetical-protein
MPSQKSQKIDLNAEYPCPCRRRGRLVPITLTEALGCDRCQNIFVVTEDGQGIEQLPTNSPYKRCWNWNGNQWCVANTRLRESYLPMSLVIVIGLVVFWLPYALGLPLGPSVIPWVILAVLLATLPALMVWLAYRR
>NC_019693.1|WP_015151720.1|7206371_7206974_-|6,7-dimethyl-8-ribityllumazine-synthase
MAVFEGTFTPTEGLRFAIVISRFNDLIVGKLLQGCEDALKRHGVDVDPQGTQVDYVWIPGSFEVPIVARQLALSGRYDAVICLGAVIRGQTPHFDYVAAEVSKGIAAAGYQTGVPVIFGIITADTMQQALERAGVKSNKGWDYGMNALEMASLMRRLNQVGPGEGSGSHGAALSKGDRSLPASTLNPSGSAQVFTNVEGA

Crispr_ID: NC_019693_77

• CRISPR_ID: NC_019693_77
• CRISPR_location: 7414177-7414267
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_77

Consensus_repeat	Method
TAGCCCCACCCTTCAGGGTGCGGGTT	CRISPRCasFinder

spacers of NC_019693_77

>77.1|7414203|39|NC_019693|CRISPRCasFinder
GTCGGTTTTCTTAGCCCGCGCAGGCGGGCTTTGTCCGTA

CRISPR arrays and Neighbor proteins around NC_019693_77

CRISPR arrays

The CRISPR arrays of NC_019693_77

>merge|NC_019693|77|7414177-7414267|CRISPRCasFinder
TAGCCCCACCCTTCAGGGTGCGGGTTGTCGGTTTTCTTAGCCCGCGCAGGCGGGCTTTGTCCGTATAGCCCCACCCTTCAGGGTGCGGGTT

>NC_019693|77|75|7414177-7414267|CRISPRCasFinder
TAGCCCCACCCTTCAGGGTGCGGGTT	GTCGGTTTTCTTAGCCCGCGCAGGCGGGCTTTGTCCGTA
TAGCCCCACCCTTCAGGGTGCGGGTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015151864.1|7423713_7424706_-|hypothetical-protein	unknown	unknown	gnl|CDD|237865
NC_019693.1|WP_015151865.1|7424730_7425789_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151848.1|7404642_7404978_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044198180.1|7417077_7417440_-|50S-ribosomal-protein-L19	unknown	unknown	gnl|CDD|235418
NC_019693.1|WP_015151863.1|7421525_7423439_+|molecular-chaperone-DnaK	unknown	unknown	gnl|CDD|234715
NC_019693.1|WP_015151857.1|7415789_7416428_-|transcription-termination/antitermination-protein-NusG	unknown	unknown	gnl|CDD|180161
NC_019693.1|WP_015151847.1|7403679_7404450_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|226983
NC_019693.1|WP_015151849.1|7404986_7405574_-|EndoU-domain-containing-protein	unknown	unknown	gnl|CDD|373068
NC_019693.1|WP_015151853.1|7412949_7413339_-|50S-ribosomal-protein-L7/L12	unknown	unknown	gnl|CDD|214358
NC_019693.1|WP_015151852.1|7411560_7412841_+|response-regulator	unknown	unknown	gnl|CDD|226702
NC_019693.1|WP_044196099.1|7405836_7407171_+|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl|CDD|224938
NC_019693.1|WP_015151861.1|7418517_7419705_+|deoxyhypusine-synthase	unknown	unknown	gnl|CDD|179117
NC_019693.1|WP_015151855.1|7414504_7415221_-|50S-ribosomal-protein-L1	unknown	unknown	gnl|CDD|177051
NC_019693.1|WP_015151856.1|7415346_7415772_-|50S-ribosomal-protein-L11	unknown	unknown	gnl|CDD|234661
NC_019693.1|WP_015151862.1|7420620_7421193_+|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl|CDD|107221
NC_019693.1|WP_015151851.1|7407650_7411568_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|236842
NC_019693.1|WP_015151845.1|7401986_7402661_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151846.1|7402727_7403432_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_044198179.1|7416424_7416646_-|preprotein-translocase-subunit-SecE	unknown	unknown	gnl|CDD|236066
NC_019693.1|WP_015151854.1|7413484_7414036_-|50S-ribosomal-protein-L10	unknown	unknown	gnl|CDD|234632

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015151864.1|7423713_7424706_-|hypothetical-protein	gnl|CDD|237865	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional.	4.14936e-13
NC_019693.1|WP_044198179.1|7416424_7416646_-|preprotein-translocase-subunit-SecE	gnl|CDD|236066	PRK07597, secE, preprotein translocase subunit SecE; Reviewed.	3.81706e-15
NC_019693.1|WP_044198180.1|7417077_7417440_-|50S-ribosomal-protein-L19	gnl|CDD|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	1.87819e-59
NC_019693.1|WP_015151863.1|7421525_7423439_+|molecular-chaperone-DnaK	gnl|CDD|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NC_019693.1|WP_015151857.1|7415789_7416428_-|transcription-termination/antitermination-protein-NusG	gnl|CDD|180161	PRK05609, nusG, transcription antitermination protein NusG; Validated.	3.49234e-88
NC_019693.1|WP_015151847.1|7403679_7404450_-|Uma2-family-endonuclease	gnl|CDD|226983	COG4636, Uma2, Endonuclease, Uma2 family (restriction endonuclease fold) [General function prediction only].	1.48258e-14
NC_019693.1|WP_015151849.1|7404986_7405574_-|EndoU-domain-containing-protein	gnl|CDD|373068	pfam14436, EndoU_bacteria, Bacterial EndoU nuclease. This is a bacterial virion of EndoU nuclease. It is found at C-terminal region of polymorphic toxin proteins.	6.50695e-24
NC_019693.1|WP_015151852.1|7411560_7412841_+|response-regulator	gnl|CDD|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	1.69697e-68
NC_019693.1|WP_044196099.1|7405836_7407171_+|D-alanyl-D-alanine-carboxypeptidase	gnl|CDD|224938	COG2027, DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Cell envelope biogenesis, outer membrane].	4.84254e-45
NC_019693.1|WP_015151861.1|7418517_7419705_+|deoxyhypusine-synthase	gnl|CDD|179117	PRK00770, PRK00770, deoxyhypusine synthase.	0
NC_019693.1|WP_015151855.1|7414504_7415221_-|50S-ribosomal-protein-L1	gnl|CDD|177051	CHL00129, rpl1, ribosomal protein L1; Reviewed.	7.69815e-149
NC_019693.1|WP_015151856.1|7415346_7415772_-|50S-ribosomal-protein-L11	gnl|CDD|234661	PRK00140, rplK, 50S ribosomal protein L11; Validated.	4.71308e-98
NC_019693.1|WP_015151862.1|7420620_7421193_+|Hsp20/alpha-crystallin-family-protein	gnl|CDD|107221	cd06464, ACD_sHsps-like, Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are generally active as large oligomers consisting of multiple subunits, and are believed to be ATP-independent chaperones that prevent aggregation and are important in refolding in combination with other Hsps.	2.11235e-22
NC_019693.1|WP_015151851.1|7407650_7411568_+|PAS-domain-S-box-protein	gnl|CDD|236842	PRK11091, PRK11091, aerobic respiration control sensor protein ArcB; Provisional.	7.75609e-90
NC_019693.1|WP_015151853.1|7412949_7413339_-|50S-ribosomal-protein-L7/L12	gnl|CDD|214358	CHL00083, rpl12, ribosomal protein L12.	1.09373e-58
NC_019693.1|WP_015151854.1|7413484_7414036_-|50S-ribosomal-protein-L10	gnl|CDD|234632	PRK00099, rplJ, 50S ribosomal protein L10; Reviewed.	3.33032e-65

Protein sequences

>NC_019693.1|WP_015151854.1|7413484_7414036_-|50S-ribosomal-protein-L10
MGKTLADKQAMVTELKQELSKSQMTLVIDYKGLTVAEITDLRRRLRESGATCAVAKNTLMRRAVDGDENWQSLGEFLKDSSAFLFLKDDLNGPIKAYQDFQKVTKKSELRGGVLEGKALTFEQVKAIGDLPSKEELMAQIAGALNAVVTKIAVGIKEVPSGLARGLQAYADKDGSTSDEDQAA
>NC_019693.1|WP_015151853.1|7412949_7413339_-|50S-ribosomal-protein-L7/L12
MSAATDEILEKLKSLTLLEASELVKQIEEAFGVSAAAPAGGMMMMAPGAAAAAEEVEEKTEFDVILEEVPADKKIAVLKVVRVLTGLGLKEAKDMVESAPKPIKEGITKDAAEDAKKQLEEAGGKVSIK
>NC_019693.1|WP_015151852.1|7411560_7412841_+|response-regulator
MNSDQPLGTLADILIVDDEPNNLRLLSNLLKKQGYKVRAVLSGEMALSAAKSTPPDLILLDIMMPDMDGYQVCHQLKNDSETCQIPVIFVSAKDQGFDKVKAFAVGGVDYITKPFQVEEVFARMECHLKLNYLQMKLEEQNYQLQAEICQRNAAEKALKEQNEQLNREIKRRQITEIALQRANQELARSNADLEQFAGIASHDLRSPLATINGYAQLLQMCGKEQLDDKCNEFLEQILKLCNRTNLLIGELLSYARLNQVQESCQLLPSDRLVQQALEHLGMEIYQNKAQVTYDPLPEIIATESQFLQLFQNLIGNAIKYRGEESPRIHLSAVLQDNCYLFSIQDNGIGIEEQYSEHIFQIFKRLHAQDYPGTGIGLATCRKIVERHGGSIWIKSEVGQGSIFYFTVPTEQRVVERQMIEAIGHPN
>NC_019693.1|WP_015151851.1|7407650_7411568_+|PAS-domain-S-box-protein
MTYRISRVATAFVIFMGAIHLLGWHFNLEWFTNGLAENPYRMKPNTALCFVFCGTALGLLQHQRLTRRWQSLVWGLAGVVIAIASLTLIQYIFGWNFGIDELLVPHLRASPTTPYPGRMGESVALNFIFIATSLLLLAQQTPRHDRLAQILTLIVALIALVPLVGHLFGSAVLYELLVSTTSTAFNTALTFLLLSVGILFTRPQQGLMQTILSPLAGGMIARRLLPWAIALPLALSWLIFQGYKLEWYDPRTAYACLIISEIVIFSIGIYIQAQVINRIEGDRQESQRWFQSAIMNSPVPIMLHAEDGEVLQINTTWSRISGYQLADIPTLNDWTEKAYQDRTKNPREPIQKIYALEAGQVLEKEQTVRTKTGENLVWYFYAVTLGKTGDRRKITMSTAIDITVRKQAEQALLELNQTLEKRIAKRTIELEQQLHQRQQIEANLRASQALLNSLIECNTDIITAMDTDYNCLVANEAAKTEFSKLFGRSFDVGDNLLEALSHLPSGQANAREVWERAFRGENFSIILELGELPQDRAYYELNYSSMRDASGEILGASLMSRNVNARIKADQALRESEARFQAFMNHSPALAWISDREGKIVYSNQNLASLFGQSVEELLGKTPFDLHPRDIAEQHVANTRLVADGGEVVEAIESAFRSDGSLGEFLVYKFPIEIDGGEHLVGGVGLNITNQIQAEKALRESEAKLKAILDNAPAGIFLKDLQGKIVLANQYILDLLQISEEQCLGKTSAELIPGEFSEQIDAQERNLLENGVPYSCEEYLPQPDGIHTYYTVKLILHDLSGQPYGICGITTDISDRKRAEIALLEAKEAAEAANLTKSAFLANMSHELRTPLNAILGFSQILAQDSSLNPPQREQIAIINSSGEHLLNLINDVLEISKIEAGRSALHLSSFDFYSLITGLEAMLQVKAASKGLQIIFDRDSVPQYITTDESKLRQVLTNLVGNAIKFTREGGVSLRVRATELKETDLEPASRFCFYFEIEDTGMGIAEEELPGLFTPFHQTATGRNASEGTGLGLSISRKFVQMMGGDIEVSSRLNVGTLVKFTIQVSVAQASDLQTASRVQRIIGLEPDQPSYRILVVDDRPESRRLIRCYLEPLGFEVREAENGQQALEVWENWEPHLIVMDMQMPVMNGYEATRQIRSHLKGQATVVIALTASAFEENRSLILSAGCDEFLRKPCRQEVLLETFAQHLGVRYRYEDPESGVEDKGDSWDATFIPDPSALQGMPLPWIGALHNAALAADSEAIEELIQEIPEGSGAIAHCLQDWTDNFRFDKITELTQELLYE
>NC_019693.1|WP_044196099.1|7405836_7407171_+|D-alanyl-D-alanine-carboxypeptidase
MLKTPRLTAAVLVTLSVLMTACNPSEAPQTEVPSAEASIAEIPTPEPPQTPKIAPLDNPDPTVTAAIAQYINSLSSQGFASENQGIWMQSGETLLAQHQGTTPLPAASLTKIATSLVALQTFGPEGEFVTQISATGPIENGELQGDLVIQGEGDPLFVWEEAMAIGNRLNEMGIQRVTGDLVILDKFYMNFETDPTIAGNLFLEGINGQIWPGEAETQYQTLPPGTARPQVAIAGTVRVAAAPPAELQPLVRHYSLPVVELLKRMNQYSNNPMAEMFADAVGGPQVVSQKAAVAAGVPPQEIQLINGSGLGEENIMSPRAACGLFLALERELQPHNMTIGDAIAIVGQDEGILNQRQIPRFSVVKSGSLNYVSALAGALPTQTQGSVWFVIMNGGSNLEGFRVQQEALLTQFVTQWGSVTALPPELSPNPLRKTKTSRSEIVKQ
>NC_019693.1|WP_015151849.1|7404986_7405574_-|EndoU-domain-containing-protein
MNHRFGQLLNGKSIRQIGIGAVVCLLVALFQGIAQGQGINCGSSSPWVTAYNNQQVNHAHIFCGEVNREGRLVGFHARPRGQNPSTVRQFRVTQSVNNQGIYGGEWSHTSGGGSKFSTMFPDRCTAEQVINSIAYAAANRVQCPSGAPHWAWCGLNAPTDSSQQTRFCTANNGSSYRIAGASNRDGKINTGFPLR
>NC_019693.1|WP_015151848.1|7404642_7404978_-|hypothetical-protein
MTEKACNEADWFDQSNAHRRVLEFLTLDIQNSQEWVQQLLDKIAALETGAINEWTRSGNAYYLIFSPQTVTIENLLVDGEPIETISLQEFKEAVLIWQEQLDNSVSDFRNI
>NC_019693.1|WP_015151847.1|7403679_7404450_-|Uma2-family-endonuclease
MTKSELTPELQTPIWVEDEWTPPMPPTDLIFDDGEPLESNRHRIAINVLIAAVHEAFAGRQDYFTGGNMFVYFSSEQALNRDFQGPDFFVALNVNETKERQGWVAWDEGGRYPNVIIELLSPSTAREDLGSKKDFYEQTFRLPDYFVYDPFAPESLRGWQLKGQRYEELTKDDRGWLWCNSLGFWLGTWEGTLQQETATWLRFFDGDGNLILLPEELAKIERQRAENEAQRAEEALSELEALKARLREKGIDLESL
>NC_019693.1|WP_015151846.1|7402727_7403432_+|hypothetical-protein
MRPDLENAIVTESELEVIAGVDVNDIGLSLAYRPAFLQNLNKLISFAIAQLFILVVFFILLTPLGILMVRNSGLSGEEMATTFYFLIFTGGIAGVATFTVNWYLWKRSQKFQTFLTLLDEIQKYNEVLRSLDILDKIEAAGGEIQLSDRQEVIEALSITRESLLGSLRTDRILRENQDLIDRRYELFAKIENNLATLNHLKISDEATEYGRLLNQALKIGVSVDREIRRLQNRS
>NC_019693.1|WP_015151845.1|7401986_7402661_+|hypothetical-protein
MNYFSVLIKLLQDRQSFLEEIHKGVKLTNKIIALLISSAIFFGIYGAIIGASHSWMQVISSFFKLPALYLLTLLICFPTLYIFSIIFGSKRSFTQYLTLLMTAEAIMSAILFGFAPVTLFFLISTQSYEFFLLLNVAILGMAGFLGIKFFYEGMQLLAEPEITGQDTRTKLLQFWLLLYAFVGTQMAWTLRPFFGSSGDFQLFRDLEGNFYVNVLQLVGRLLGY
>NC_019693.1|WP_015151855.1|7414504_7415221_-|50S-ribosomal-protein-L1
MPKKISRRLQELVKKVEERPYEPLEALNLLKETATAKFPESAEAHIRLGIDPKYTDQQLRTTVALPKGTGQTVRVAVIARGEKVNEATQAGADLAGSEDLIAEIQQGRMDFDKLIATPDMMPQVAKLGKLLGPRGLMPSPKGGTVTFDLGQAINEFKAGKLEFRADRTGIVHVMFGKAAFPTEDLLVNLKALQESIDRNRPSGAKGRYWRSVYVTSTMGPSIEVDISALRDLKLTETA
>NC_019693.1|WP_015151856.1|7415346_7415772_-|50S-ribosomal-protein-L11
MAKKVVAVIKLAINAGKANPAPPIGPALGQHGVNIMMFCKEYNARTADQAGLVVPVEISVFEDRSFTFILKTPPASVLIRKAAGIERGSGEPNRKKVAEISRDQLREIAQTKMPDLNANDIEAAMKIVEGTARNMGVTVGD
>NC_019693.1|WP_015151857.1|7415789_7416428_-|transcription-termination/antitermination-protein-NusG
MMFASDDDSQYPTQPSETDETEETKSTGRWFAVQVASGCEKRVKATLEQRIQTLDMGDRIFQVEIPQAAAFKIRKDGSRQQTDEKIFPGYVLVQMDMDDESWQVVKNTPHVINFVGAEQKRRYGRGRGHVKPMPLSYSEVQRIFRQRDEAEPVAKTYLTPGEKIEVVSGPFKDFDGEVIEVSPERSKLKALLSIFGRDTPVELEFNQVRKLS
>NC_019693.1|WP_044198179.1|7416424_7416646_-|preprotein-translocase-subunit-SecE
MAKKNEADQETASGFNPAEFFQETKEELAKVVWPSRQQVISESLAVLSMVALIASLIYFIDKFFGWAATQVFG
>NC_019693.1|WP_044198180.1|7417077_7417440_-|50S-ribosomal-protein-L19
MKAEQIIRAIEAEQLKTDLPQIYVGDSVRVGVRIREAGKERTQPYEGVVIAMRNGGINETITVRRVFQGVGVERVFLVHSPRIESIKILRRGKARRAKLYYLRDRVGKATRIKQRFDRPI
>NC_019693.1|WP_015151861.1|7418517_7419705_+|deoxyhypusine-synthase
MSQMIDRKIAPAPMTENVSVVDLIDSYFTAYNSARLREICHLLTQKVMREGVTVGLSLSGAMTPAGFGVSALAPLIRNGFIDYIISTGANLYHDIHYGLGLNLYAGNPFVDDIKLREEGHIRIYDIIFDYDVLLETDAFIRTILRAEPFQKRMGTAEFHYLLGKYVSEIEKQRGVEHSCLLATAYECGVPIYTSSPGDSSIGMNVAALALEGSELIIDPAIDVNETAAIAYGARDPNQDFPGESAAFILGGGSPKNFLLQTQPQIHEVLGLEERGHDYFIQITDARPDTGGLSGATPSEAVSWGKVDPNELPNTVVCYTDSTIALPILTAYVMNQCPARSLKRLYDRRQEMLTKLQLDYQLAQAKKSERTAPPVSERPEPVATYPCGTPIRKGRG
>NC_019693.1|WP_015151862.1|7420620_7421193_+|Hsp20/alpha-crystallin-family-protein
MRTLMNLDLLREVDAWGRQFEQLLTEQPPCQRPEMGRVWQPAIELEETENSFVLRVEVPGLTGEEIDVQASRFQVAIAAQRQPPTPVSQNSGYLRSELNYGKLRRVVPLPKPIVPDRIEAQLNNGILTLTLPKFSAQQTQVVKVRLDELKSKVNPVMPVEQKPDLTPQKTEEKIAPSEGEVLTDLWATPG
>NC_019693.1|WP_015151863.1|7421525_7423439_+|molecular-chaperone-DnaK
MGKVVGIDLGTTNSCVAVMEGGKPTVIANAEGFRTTPSVVAYTKNSDRLVGQIAKRQAVMNPENTFYSVKRFIGRKHTEVTHETTEVSYKVLNINGNVKLDCPALSKQYAPEEISAQVLRKLVDDASTYLGEKVTQAVITVPAYFNDSQRQATKDAGKIAGIEVLRIINEPTAASLAYGLDKKSNETILVFDLGGGTFDVSILEVGDGVFEVLATSGDTHLGGDDFDKKIVDFLAEEFRKAEGIDLRKDKQALQRLTEAAEKAKIELSSVTQTEINLPFITATQEGPKHLDTTLTRAKFEELTADLIDRCGIPVENAVRDAKLDKSAIDEVVLVGGSTRIPAVKELVKKVLGKEPNQTVNPDEVVAVGAAIQAGVLAGEVKDILLLDVTPLSLGVETLGGVMTKIIPRNTTIPTKKSEVFSTAVDGQTNVEIHILQGEREMANDNKSLGTFRLDGIPPAQRGVPQIEVTFDIDANGILNVHAKDKGTGKEQSISITGASTLPGDEVERMVREAESNATADKERREKIDLKNQADSLTYQAEKQMSELGDKVPADEKTKVTDLIQALKDAIAKDDLELMKSQMTELQQALYAIGSKIYEQSGGAEGGPPNDNGDGGAGTPPSGGSDEDVIDAEFSETK
>NC_019693.1|WP_015151864.1|7423713_7424706_-|hypothetical-protein
MNHKFLYQYCAVGLGLCGVIFLSAYPVQAQAQSPVSGSMMGSEIVPPPPIAPAPQITPPPVVEPAPVQPPPVVEPAPVQPPPVQPAPVQPPPVVEPAPVQPPPVQPAPVQPPPVQPPPVQPPSVQPAPVQPPPVLEPTQVQPPPIPTETPSVPSTSGGSETNPSSGLQGQEGVITTTGDIGGFGSGTGSQTVFAGRGDAQSAVNEAGNNVLAQLNAGNLNAVSGASVSFEAQQLVAAVLTTGEVNSVNALSTALSSTPGAPSVEATRRLASKLARLLADGQVNAEELLDAIRSYNEMIQQSNSEFLRNPPAELLAIQVALSRLIEAAGVG
>NC_019693.1|WP_015151865.1|7424730_7425789_-|hypothetical-protein
MRQKLLAKYLGIGTTQRSKRLLLAIASFLGATLYNTIASANPVPLNDNNEQPEAIAWELPSETTQFALPFTSPTAEALQVEERSFNTFFRAQEAIVAQEPTSTDSDLETLRNQYLLPEPATLVVPTAGGSSAPGVSIGTPTAFGANWGRVYTGFGYQERTRYTTKADGTLALGFGLGNSRENVGLEVSLVVTDLIDETLADGGVSFKVHRLLPNNFAVAAGVEYALSWGDIDTTSSPYGVVTKIFRFKENSAEPLSQLTVSLGVGGGRYRSEDDVINDNNTIGVFSSVGLRVVEQISLIADWTGQDLFLGASIVPFKDLPLVITPAFADITNNAGDGARFILGIGYGYTLAF

Crispr_ID: NC_019693_78

• CRISPR_ID: NC_019693_78
• CRISPR_location: 7437152-7437262
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: RT

Consensus repeat of NC_019693_78

Consensus_repeat	Method
TGCAACAACCGGCGGGGGATAAATCAAGCGCCTAACAG	CRISPRCasFinder

spacers of NC_019693_78

>78.1|7437190|35|NC_019693|CRISPRCasFinder
CTTGCATTCGGTTGAAACTGAGATCTTGCACCTGC

CRISPR arrays and Neighbor proteins around NC_019693_78

CRISPR arrays

The CRISPR arrays of NC_019693_78

>merge|NC_019693|78|7437152-7437262|CRISPRCasFinder
TGCAACAACCGGCGGGGGATAAATCAAGCGCCTAACAGCTTGCATTCGGTTGAAACTGAGATCTTGCACCTGCTGCAACAACCGGCGGGGGATAAATCAAGCGCCTAACAG

>NC_019693|78|76|7437152-7437262|CRISPRCasFinder
TGCAACAACCGGCGGGGGATAAATCAAGCGCCTAACAG	CTTGCATTCGGTTGAAACTGAGATCTTGCACCTGC
TGCAACAACCGGCGGGGGATAAATCAAGCGCCTAACAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015151874.1|7436122_7436875_-|serine-O-acetyltransferase	unknown	unknown	gnl|CDD|223975
NC_019693.1|WP_015151871.1|7434177_7434474_-|nucleotidyltransferase-family-protein	unknown	unknown	gnl|CDD|224583
NC_019693.1|WP_156823996.1|7435536_7435824_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151877.1|7438427_7439498_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NC_019693.1|WP_015151878.1|7439846_7440974_-|AI-2E-family-transporter	unknown	unknown	gnl|CDD|223701
NC_019693.1|WP_015151868.1|7428372_7428984_-|hypothetical-protein	unknown	unknown	gnl|CDD|372967
NC_019693.1|WP_015151881.1|7444998_7448220_+|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911
NC_019693.1|WP_015151870.1|7431316_7433941_-|signal-peptidase-I	unknown	unknown	gnl|CDD|274044
NC_019693.1|WP_044196104.1|7442638_7444492_+|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|273776
NC_019693.1|WP_156823998.1|7444715_7444862_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151879.1|7441146_7441992_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151875.1|7437378_7437864_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151872.1|7435082_7435577_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151867.1|7427371_7428343_-|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl|CDD|379142
NC_019693.1|WP_015151873.1|7435806_7436004_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151869.1|7429538_7430420_-|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl|CDD|275105
NC_019693.1|WP_015151866.1|7425898_7427326_-|hypothetical-protein	unknown	unknown	gnl|CDD|379142
NC_019693.1|WP_015151883.1|7451065_7452235_+|anhydro-N-acetylmuramic-acid-kinase	unknown	unknown	gnl|CDD|236579
NC_019693.1|WP_156823999.1|7449033_7450809_+|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209
NC_019693.1|WP_156823997.1|7438145_7438304_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_156823999.1|7449033_7450809_+|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	7.7e-46	151.1	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015151874.1|7436122_7436875_-|serine-O-acetyltransferase	gnl|CDD|223975	COG1045, CysE, Serine acetyltransferase [Amino acid transport and metabolism].	7.59419e-99
NC_019693.1|WP_015151877.1|7438427_7439498_+|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	7.32879e-82
NC_019693.1|WP_015151868.1|7428372_7428984_-|hypothetical-protein	gnl|CDD|372967	pfam14218, COP23, Circadian oscillating protein COP23. This family includes the circadian oscillating protein COP23 from Cyanothece sp. (strain PCC 8801). The levels of this peripheral membrane protein display a circadian oscillation.	1.17704e-59
NC_019693.1|WP_015151881.1|7444998_7448220_+|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NC_019693.1|WP_015151878.1|7439846_7440974_-|AI-2E-family-transporter	gnl|CDD|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	4.82056e-48
NC_019693.1|WP_015151871.1|7434177_7434474_-|nucleotidyltransferase-family-protein	gnl|CDD|224583	COG1669, COG1669, Predicted nucleotidyltransferases [General function prediction only].	1.24098e-21
NC_019693.1|WP_015151870.1|7431316_7433941_-|signal-peptidase-I	gnl|CDD|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.84045e-18
NC_019693.1|WP_015151867.1|7427371_7428343_-|trypsin-like-peptidase-domain-containing-protein	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	7.51337e-24
NC_019693.1|WP_015151869.1|7429538_7430420_-|ParB/RepB/Spo0J-family-partition-protein	gnl|CDD|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	4.07931e-44
NC_019693.1|WP_015151866.1|7425898_7427326_-|hypothetical-protein	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	2.93249e-18
NC_019693.1|WP_015151883.1|7451065_7452235_+|anhydro-N-acetylmuramic-acid-kinase	gnl|CDD|236579	PRK09585, anmK, anhydro-N-acetylmuramic acid kinase; Reviewed.	2.06645e-175
NC_019693.1|WP_156823999.1|7449033_7450809_+|group-II-intron-reverse-transcriptase/maturase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	2.58351e-122
NC_019693.1|WP_044196104.1|7442638_7444492_+|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	4.49174e-35

Protein sequences

>NC_019693.1|WP_015151874.1|7436122_7436875_-|serine-O-acetyltransferase
MLNTLVADFQIIFERDPAARNWLEVLFCYPGLQALLFHRVAHWLHQVGIPFIPRLISHLGRFFTGIEIHPGAAIGRGVFIDHGMGVVIGETAIVGDYSLIYQGVTLGGTGKESGKRHPTLGENVVVGAGAKVLGNIQIGNNVRIGAGSVVLRDVPSDCTVVGVPGRILYRSGVRVNPLEHGQLPDSEASAIRSLLDRIEALEQQVQDMKPQKPSFVFVGASSEKFCLEQLPPNCNLNNKAIQEFLDGSGI
>NC_019693.1|WP_015151873.1|7435806_7436004_+|hypothetical-protein
MFQTIQANLPILYFLAVAHCIMGLLAAGVAQRKGYNRGLWLIWGLIGGTVAFVTASRLKPKTDVF
>NC_019693.1|WP_156823996.1|7435536_7435824_-|hypothetical-protein
MDSLEQGDRPLMLDDKWSLRITSDSMPVPVCTNGDSIHKHRCRLSYQLSLLKAICTFKPFLPEEWWRRLPTRFGAVASIASEVTRQWWILERDRE
>NC_019693.1|WP_015151872.1|7435082_7435577_+|hypothetical-protein
MVQYTIAQSPEIILTVSGRDSTKARDKAMDQLLEMMDEGKLPTKLSNKLSEGFSPDEFIEVKEPEGLDENSDDALTEAVQILSSLVTLKEKVDKSHAEALKVREQIDVLFQDRPVTEEEIANLKEGFKTLKTFAQANQRYQAAREQAEEARTILDRVLKSTTAE
>NC_019693.1|WP_015151871.1|7434177_7434474_-|nucleotidyltransferase-family-protein
MTTSLRELLQEKREEILKIATKHGAYNLRIFGSVARGEERQDSDVDFLVDMESDRNLLDRIGLMQDLEDLLGRKVDVATVKVLRDFCREGILKDAVPL
>NC_019693.1|WP_015151870.1|7431316_7433941_-|signal-peptidase-I
MTPELFNLLKLIPYAILLVVGGLSINAYGQRVTHRGQKQIVLGIALLASFLGVWLNAVEVSQLEQQPNSVYVSFGLSTGFGLSALAYLRWLYGQSKQREAESQLRQGLLERISKDVEGRRQDSLDNFYHIPVYGVQQSPGSHGLFRPIQVVVGQKTRLLDVSISKLFFQEDVGGQLLILGERGSGKTTELLGLAQTLCKRAQEDPQAPIPIIFELSNWRPSRQPIEAATLNHWMVEQLQLKYGLDPQLSQDWLHRKRLIPLLDGLDELKNFMTEAIGAINSMQEDEKERHLKLIVCSRFQDYQDCQERLSLKTAVYLKPLENEAIQAYLKHRNASHLWKVLKASPQGWLKLAKTPLLLDLMPRAYPAPIVPDCPDQAGEAACRHRLFEDYSHRQLTLKHNSEYSEEDSRRYLQQLAQILRRQGQTEFLIEEMQPDWLETPRQTRWFNSGGSLIGGLIVGLIGGLMFGLIVGLIFGLMFGLIFGLIVYPKKQIELTESFDLSGSNIKGAVLDSWIFGLIAGLIVGLICGLIGWLIGDLIRGLIVGLMCGLIVGLKGGLFVGLKAKLKVKSYPNQGIWESLKKSAIVSVLTTPIWMMEFLLIDDLLLRAGQEPIFGNPAAVVILGIGMGLLTGAFLGGLNSVLRHVLLRWILFQNQVIPWNYARFLTYASEQGLLKQSGGRFRFYHDLLREHFAGEDTARPQLTLAPPSRLWLNWTLTVMLFLGGLLLIRNVQTVGINTAVMMSPTLEAQEQVLTDELTYGYRTPQRGDIIIIKSADTLANREGRFYIRRILALPHETLEIRQGQALINDRPLKTITLSPRYELHSLTLAADEYFVVGDNDAVEELEEFAEIVPRHRIHAQVLLRLSPLSRWGRLD
>NC_019693.1|WP_015151869.1|7429538_7430420_-|ParB/RepB/Spo0J-family-partition-protein
MDTQNTQRHISTFLSSKTLRLEQICQSQFQPRNYFNEVAMEELAASIKEHGILQPLLVRPIAANEYELVAGERRYKAAQALGLKDVPVTVREMTDPEVLQYALVENLQREDLNPVEETEGILQLLEMRLQKDRDWIISLLNYMANGKRGFTDSAVRNREQQLMQEVFATIGRRITPESFRTHRLPLLKLPPELFEALRYGRIEWTKAKEIAKLESESERLALLDRAIAQSLSLRTIQKIVRAQKTPRDSAQQQREVEGLLQQFTQLKAWENPDKRYKMESLLTELKQLITEPD
>NC_019693.1|WP_015151868.1|7428372_7428984_-|hypothetical-protein
MKAKFAITSILTAAAVAIGATVTLQQPAQANTRFVCAMSSTTGLPTTFAMTPRGPVPVVRWYSEYFSASGYSPERRCQEVSGRFNNLHSQGLLSSITTGYLNGQPVVCASRSGGCNNSNLLFTLKSGVDAAAAVQQLFDLQRGTASGPLYESSGDDGVNIDFNNFLSNAAVDPSGPSSGGSEGTNVTPSEPSEPSGVGGGGIW
>NC_019693.1|WP_015151867.1|7427371_7428343_-|trypsin-like-peptidase-domain-containing-protein
MNLRSQIVLICVGSFLITLPTQLFPLYSSAQILPRSGVTGQPSPALLADQVRDIAQRITVKVLSGRSGGSGIIIHKQGPTYTVVTNQHVLTAGQGSGYQIQTPDGRTYPGEVVRTVSFEGNDLALLQFRSTGADYMVGSVGTSSSLQPGDEVFAAGFPFESEQLGSAWTFTTGTIALIADRTIEGGYQIAYTNPVEKGMSGGPILNRQGQVIGINGMHAYPLWGDPYLFTDGSRPSTAMREIMVRSSMGIAIDTFVQLAAGFYNNSGGMPAASVPSSPMRLVSPGEQPRDSRPESAQPQVDSSGLPVVEETPGLSHPGSEPLW
>NC_019693.1|WP_015151866.1|7425898_7427326_-|hypothetical-protein
MKVYRILLAVLIGLAMALAQPYLGTAFISDSVDQVKAIAQEITVLIPETNPESGKTANGSGFLIAKQGNTYTVLTANHVVCRDQSESCQQPRPGLKVVTHDGQEHTLDFTTVKKLPEVDLAILQFNSNRNYKLAILANYDTNINSEREVQLPNGQIVQEYGHFVFASGWPGINNRDITELKYRFSVGRLLPENKMVGFRIRPVAEGYQAVYTSITYPGMSGGPVLDTDGRVIAVHGQNEGERVSNEGASGNERVLIGYSLSIPISKFLNLAPQVSIPLNNVTIQTNPARALNQDDIEAIGAEFVLAGMQEQTAAQPNSAVYWANQGNQYWRALRPPQALEAYEKAIEIDSEFYPVWYGKGLVKTFQAKYDEAFVNYNKAITILDNQIAQFPRETERQDRREWVVKLRDQIQPLMANSPTAPTTPTVNSPSPPTQSESTVQPSPSSPPPEPNITPPQPEPETQPETQPETQPGFLW
>NC_019693.1|WP_015151875.1|7437378_7437864_-|hypothetical-protein
MLTNGINPWKCTAAIALTLAFNVIPAFANPANFEPIILSRGFQPSSGVVSGFTGGSISLPAVTTVRDRQNQLCLGFGDPTPDHIMELRADFPRLTVELNSRGVDTTLIIRGPDNTFRCGDNTELSQDARISDTDWPQGTYQIWVGTKEMGVRRRYRLSVRE
>NC_019693.1|WP_156823997.1|7438145_7438304_+|hypothetical-protein
MSVIVMLVVSYVAWLLTSLLVSIPIFFLGSVRLPLQVGLFVIFLLILWTVED
>NC_019693.1|WP_015151877.1|7438427_7439498_+|ABC-transporter-permease
MNWWKKLKKNPLARLGAILLLVFYLTAIAAEFVAPYDAYISQPSGALLPPTQIYWRNQTTGDFIGPHVYPTTQGAIDLETGDRELLVDFEQPSRLGLFVRGPAYKLFGLIPGDIHLFGTTGTAPLNLLGTDDQARDQFSRLVMGARISLFIGLVGISISFPLGLMVGGISGYFGGALDSVLMRLVEVLMTIPSIYLLVTLTLILPAGISSAQRFILIVVITSFVSWSGLARVIRGQVLSIKEREFVQSAKAMGAKPLYIIVRHVIPQTATYTIIAATLSIPGFIVAESVLSLIGLGIQQPDPSWGNMLSLSTNASILVLQPWLVWPPALLIILTVLAFNLLGDGLRDALDPRSVQR
>NC_019693.1|WP_015151878.1|7439846_7440974_-|AI-2E-family-transporter
MKQVFSPFQQFLLTWLLMLGVGWATLSALSYVGEAVGILITAGLIAFLLNYAVSRLQKFLPRGIAAVGVYLLAGLLVLVVGLTVVPPVFNQGRQLIDNFPNLVKSAQEQLAGFQTWSEERNLPFDVGLLEQQIGERMQGQVQAIASRGFGLVLGTVSWFLDGVLILVISFYMLVDGDRLWRTLTWIFAPNIRDQLTTSLQRNLQKFVSGQLLLGLFMAVTLTPAFWALRVPFFLLFAVFIGVMEVIPFVGATLGIGAVFLIVAFIDWWLALQVLAVAIALQQVKDNIIGPRIMGSLTGLSPVIIFTSLLLGGKVGGFLGIILAIPLTGVIKSIVEIAIDPTLPPQTGSFFNNILSQKPPQALPAETGISEGDRLR
>NC_019693.1|WP_015151879.1|7441146_7441992_-|hypothetical-protein
MLNTTEILIDNFVQKLREGYRRTYGGYKPDYEDIIAWAGSMALENIANSDALYHNVEHTILVTLVGQEIMRGKHIREGGVSCDGWLHFIISLVCHDIGYVKGVCRQDKNGWYATGQNGKMIELKPGSSDAGLTPYHVDRAKLFIDERFGGHTLIDAEQIKYNIELTRFPVPKAEDHQDTINYPGMVRAADLIGQLSDPRYLKKIGALFYEFEETGTNAVLGYKHPGDLRKNYPKFYWNGVFPYVKDALEYLSLTQEGKQVIANLYSNVFVVEHESAQAELA
>NC_019693.1|WP_044196104.1|7442638_7444492_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MRKGAFSQAETEDTMENPGIQDSQRLYQESDVEWERVEDSEESSGTTGLAAPPRTSDWKKLIVGVGIGVAIAVGGMQLLNNRPQDETAENSSGVAAETPNAQPAANQTVTVAIAESARVERSLDTTGTVQAYDLLPVLPQASGLQIQQVLVDEGEVVEAGQVLAILDDAVERSQITEAEAQIDSARSTVADRQAAIAIAEAAVSQALATQSEAEAAVATAIAAKAEVEAGEGQVMAGLAEATSGVSQAVAAKAEAEAGLEQTRASLAQAQAELAQAERERDRYQQLAEAGAVSTQELETRSTAAENARERVRVAEANIRSAQARIASSDANIASMRSRVVSANSNIEISKARVQSAESNVNSAQARLESAIANVQIARSQLDSARANANSSAASLRSTQARAQQVETQQERTVVRAPKAGIIAERVARVGDVTSNTKQLFSIIANGQLELQVRIPETQLSQIQIGAPVQVTSDADSRINVAGTVREIAPLVDEESRQATVKVSLPSDSILRPGMFLRAGITTSAAQAITIPGKAVLPQADGGAIVYRLVGQDIVQAQPVEVGEVASGSPTDLSSTRVEIRSGLSLGDRVVVEGAAYLKDGDRIRIADDINPTPQVEL
>NC_019693.1|WP_156823998.1|7444715_7444862_-|hypothetical-protein
MTSGPLPLARGGLGWGSSWPIATSRTLYGLSTCMEPGANLFHREARSR
>NC_019693.1|WP_015151881.1|7444998_7448220_+|efflux-RND-transporter-permease-subunit
MSFHISTWSIKSPVPTLVLFLILTVVGWMSFGQLGIDENPNIDIPIVSITVTQTGAGPTELETQVTRKVEDAVAGLGNIDELNSTVTDGISTTTISFILGTDSDRATNDVRNAISQIRQDLPADINDPIVSRLDFAGGPILTYALRSDRRSVEELSDLVDRPIARAILAVPGVAQINRIGGVDREILIELDPVRIKALGITATQINDQIRSLNINLPGGRSQVGGSENTIRTLGSAQTVEALRQNRIVLPSGEAVPLESVANVIDGFAEPQQSARFWSPEGSASPQLQATNPGEIATPVVAFSVLRSTGSTLVTVEEGVRESIQQLQQTLPDDLDFELIFTRANEIRDSYQASIDALVMGCLLTVCVVGLFLWDWRATLITGVALPLSIIPTFMVMGLLDYTLNGMTLLALSLAVGNLVDDAICMIENIDQHLKMGKRPYQAAMDAAQEIGLAVLATTATIVAVFLPVAFMGGIPGQFFQPFGVTVSVSTMFSTLVATTMTPMLSAYLLKDKHSSGQKRRSKKNPMGTASEKISNAPRRKIAPYRTALTWALKHRVITLIIAVAFFIGSLQLVPYIPTGLFNSGDTGLSTVNVELPPGSTLRESDRTAQRTIALLQQHPAVGSVLATVGSGGASRDLNTATLYVNLLPKDAREVSQQVFEQQMREEFTKIPGARISFQSAGAGGSTKDLSIVLKSENPTALQEAADTLERQMREVPGLVEVSSSASVVKPEILIKPDPQRAADLGVSVQAIARTASLATLGDNEANLAKFDLSDRQIPIRVWLSESYRNNLKAIGNLEIPSQSGRLVPLSAVADIVLGSGPAQIDRYDRARQVSIEANLQGVSLGDALAQVEALPGMTLPPGVEQQSSGDAKIMQEIFGRFIGALGLAVLSIFAILVLLYNNFLHPVTIMAALPLSIGGALLGLMVTQKELGLFALIGIVMLMGLVTKNAILLVDCTLANQQNGMRQVPAIIEAGVSRLRPIFMTALSTIAGMMPIALEIGAGGEVRSPMAIAVIGGFSISTLLTLIVVPVLFTYIDGFQNFLKNLINAKSRHRRKLKALQGKKDKIKVLGLK
>NC_019693.1|WP_156823999.1|7449033_7450809_+|group-II-intron-reverse-transcriptase/maturase
MTVAMNTVKTSLKTTETWNAIPWTKVQRKVFKLQKRIFQAAKSGQDAKARRLQKLLTSSYYARLLAVRKVTQDNQGKKTAGIDGVKSLKPKQRLELAKDLGKHSKAKALRRVWIPKPGRDEKRPLGIPIIRDRAEQALVKQALEPEWEARFEGTSYGFRPGRSAHDAIGRIYASINQGSYYVLDADITKCFDKINHEYLLSKLDCCLQHRRQIKQWLKAGVVDNGIFEDTESGTPQGGVISPLLANIALDGMARLIEELYPKRKGQKVKATLIRYADDFVVISPEIEIINQCKIALENWLKFVGLELKPEKTKICHTLREIEVNGEKVTPGFDFLGFTIRQYPVGKYKSGKTGGANSRLIGHKTHIKPSAKAIKAHSEALKGVIKNHKTAPQAALISRLNPIIRGWSNYYSGVVSMETFNQMDHNIWQQLRAWTVSRCGQANLEKLRKYFHKVTVKIGNGKERNEKWLFQAKDGLSLWKHSYTQITRHTLVKPEASPYDGNWSYWATRRGTSLEVPMRVAKLLKKHSGRCSRCGQYFAMEDLMEVDHIQPLSMGGKDEYRNLQLLHRHCHDKRRLKICRTSSRTNDNGRLN
>NC_019693.1|WP_015151883.1|7451065_7452235_+|anhydro-N-acetylmuramic-acid-kinase
MTRVIGLISGTSVDGIDAAMVNITGTEGDLQVDWIAGTTYPYPEPLRQKILAVCAGEPMSMAELTELDDAIAQTFAHAALTLQGDNSVELIGSHGQTVYHRPPQTPQLGYSLQLGRGAVIAQLTGIPTITNFRAGDIAAGGQGAPLVPKVDLYLLGDRHHYQCVQNIGGIGNVAFIPPQDPSRSPGSESPQMLGWDTGPGNSLIDLAVQYLTNGEATYDQDGAWAAQGVPCQPLLDHWLHHPFFHEPPPKSTGRELFGWDYFRDCLSDAEPYSLTPEDLLATLTELTVEAIAINYRAFLPVPPSRVLLCGGGSRNGYLKQRLQQRLQEIYGQSVAVLTTDEVGVNADFKEAIAFAVLAYWRQQGIPGNLPECTGAKIPTLLGELHVPIL

Crispr_ID: NC_019693_79

• CRISPR_ID: NC_019693_79
• CRISPR_location: 7472773-7472874
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_79

Consensus_repeat	Method
CGCCCCTACGTGAAATTATGATTTTTGTCATTAAATTT	CRISPRCasFinder

spacers of NC_019693_79

>79.1|7472811|26|NC_019693|CRISPRCasFinder
ACTACCAATTCAGGGCGCAAGCATTG

CRISPR arrays and Neighbor proteins around NC_019693_79

CRISPR arrays

The CRISPR arrays of NC_019693_79

>merge|NC_019693|79|7472773-7472874|CRISPRCasFinder
CGCCCCTACGTGAAATTATGATTTTTGTCATTAAATTTACTACCAATTCAGGGCGCAAGCATTGCGCCCCTACGTGAAATTATGATTTTTTGTCATTAAATT

>NC_019693|79|77|7472773-7472874|CRISPRCasFinder
CGCCCCTACGTGAAATTATGATTTTTGTCATTAAATTT	ACTACCAATTCAGGGCGCAAGCATTG
CGCCCCTACGTGAAATTATGATTTTTTGTCATTAAATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015151900.1|7473323_7473545_-|DUF2281-domain-containing-protein	unknown	unknown	gnl|CDD|378366
NC_019693.1|WP_015151901.1|7473729_7473933_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151897.1|7471106_7471571_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151908.1|7480067_7481498_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151890.1|7460844_7461105_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151905.1|7478656_7478896_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151906.1|7478892_7479294_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350312
NC_019693.1|WP_015151910.1|7483444_7484521_+|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340832
NC_019693.1|WP_015147345.1|7459676_7460789_-|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NC_019693.1|WP_015151891.1|7461108_7461474_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151895.1|7467194_7469423_+|photosystem-I-core-protein-PsaB	unknown	unknown	gnl|CDD|237300
NC_019693.1|WP_015151907.1|7479681_7480038_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151892.1|7461937_7462672_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|226983
NC_019693.1|WP_015151909.1|7481665_7482838_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|226925
NC_019693.1|WP_015151898.1|7471690_7472650_+|lysophospholipase-L1-like-esterase	unknown	unknown	gnl|CDD|238866
NC_019693.1|WP_015151896.1|7470634_7470847_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NC_019693.1|WP_015151894.1|7464899_7467170_+|photosystem-I-core-protein-PsaA	unknown	unknown	gnl|CDD|176996
NC_019693.1|WP_015151899.1|7473046_7473271_+|DUF433-domain-containing-protein	unknown	unknown	gnl|CDD|225291
NC_019693.1|WP_015151902.1|7474426_7474750_+|DUF4926-domain-containing-protein	unknown	unknown	gnl|CDD|379816
NC_019693.1|WP_015151893.1|7462852_7464286_-|hypothetical-protein	unknown	unknown	gnl|CDD|237868

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015151900.1|7473323_7473545_-|DUF2281-domain-containing-protein	gnl|CDD|378366	pfam10047, DUF2281, Protein of unknown function (DUF2281). Members of this family of hypothetical bacterial proteins have no known function.	0.000856902
NC_019693.1|WP_015151898.1|7471690_7472650_+|lysophospholipase-L1-like-esterase	gnl|CDD|238866	cd01828, sialate_O-acetylesterase_like2, sialate_O-acetylesterase_like subfamily of the SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	3.06465e-54
NC_019693.1|WP_015151906.1|7478892_7479294_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350312	cd18745, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily. The PIN_VapC4-5_FitB-like subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This subfamily belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	4.11612e-61
NC_019693.1|WP_015151910.1|7483444_7484521_+|glycosyltransferase-family-4-protein	gnl|CDD|340832	cd03802, GT4_AviGT4-like, UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.	2.93356e-155
NC_019693.1|WP_015147345.1|7459676_7460789_-|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.16702e-37
NC_019693.1|WP_015151896.1|7470634_7470847_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.08564e-05
NC_019693.1|WP_015151895.1|7467194_7469423_+|photosystem-I-core-protein-PsaB	gnl|CDD|237300	PRK13199, psaB, photosystem I P700 chlorophyll a apoprotein A2; Provisional.	0
NC_019693.1|WP_015151892.1|7461937_7462672_-|Uma2-family-endonuclease	gnl|CDD|226983	COG4636, Uma2, Endonuclease, Uma2 family (restriction endonuclease fold) [General function prediction only].	1.77833e-16
NC_019693.1|WP_015151909.1|7481665_7482838_-|GNAT-family-N-acetyltransferase	gnl|CDD|226925	COG4552, Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only].	6.47317e-89
NC_019693.1|WP_015151894.1|7464899_7467170_+|photosystem-I-core-protein-PsaA	gnl|CDD|176996	CHL00056, psaA, photosystem I P700 chlorophyll a apoprotein A1.	0
NC_019693.1|WP_015151899.1|7473046_7473271_+|DUF433-domain-containing-protein	gnl|CDD|225291	COG2442, COG2442, Uncharacterized conserved protein [Function unknown].	2.57447e-25
NC_019693.1|WP_015151902.1|7474426_7474750_+|DUF4926-domain-containing-protein	gnl|CDD|379816	pfam16277, DUF4926, Domain of unknown function (DUF4926). This family consists of uncharacterized proteins around 70 residues in length and is mainly found in various Caulobacter, Microcystis and Cyanothece species. The function of this family is unknown.	5.57629e-11
NC_019693.1|WP_015151893.1|7462852_7464286_-|hypothetical-protein	gnl|CDD|237868	PRK14960, PRK14960, DNA polymerase III subunit gamma/tau.	2.96186e-10

Protein sequences

>NC_019693.1|WP_015151898.1|7471690_7472650_+|lysophospholipase-L1-like-esterase
MNRPASGIQMYLQRIEGLKVGRTYTLLPPDSFKSVWEQAIGQPTYQDWTNLLAWEALALTKGQGSNRLSILLGDSISMWFPPELMPPGRLWLNQGISGDNTSGILKRLWTFSETKPHTIYILAGINDLRQGRPDASIADNIYYTVRELQLIHPPAKVVVQSILPTRLAALPNTRIRKINLELAAISKSEGAIYFDLNSGFTNDEDMLRRELTTDGIHLSQAGYQLWQKALHQMSSRLDLNRDNRYQQWLQRSPNFILDGKTYTWVSYQVQPGDSLPQLSQKAFGFDTFEYWDLIALKNNLGFEEKLGDRTILIPQTVEK
>NC_019693.1|WP_015151897.1|7471106_7471571_+|hypothetical-protein
MISNSQPSSPIIRQSKINHTSDILHPLARFVTEETVALMFGISETDIYRIDCMRHVVYVHGKGVSRFVSYADFPPIVGVASPTLPDLARWHKRWRKGWQSHHAPEFWTQFYQIQLQKSQRLEQLQAWGLLIRALKSGLSETALVELRQAYKLKK
>NC_019693.1|WP_015151896.1|7470634_7470847_-|helix-turn-helix-transcriptional-regulator
MGLVRLRIREFANEKGWNLKEVSDRSGLVYSTVRHYARSPGLALVDFTAIHKLARTFDVLIEDLVEIVEE
>NC_019693.1|WP_015151895.1|7467194_7469423_+|photosystem-I-core-protein-PsaB
MATKFPKFSQDLAADPTTRRIWYGIATAHDFESHDGMTEENLYQKIFASHFGHLAIIFLWTSGNLFHVAWQGNFEQWIKDPLNVRPIAHAIWDPQFGAPAVDAFTQAGASNPVNIAYSGVYHWWYTIGMTKNSDLYQGAIFLLVLAAVMLFAGWLHLQPKFRPSLAWFKNAESRMNHHLAGLFGVSSLAWTGHLVHVAIPESRGVHVGWDNFLSVKPHPAGLAPFFTGNWGVYAQNPDSAGHVFGTAQGSGTAILTFLGGFHPQTESLWLTDIAHHHLAIAVLFIIAGHMYRTNFGIGHSMKEIMDAHNPPKGTPFGGLLGEGHKGMYDTYNNSLHFQLGWHLAALGVITSLVAQHMYSLPPYAFMARDYTTQAALYTHHQYIAGFIMVGAFAHGAIFLVRDYDPEANKNNVLYRVLEHKEAIISHLSWVSLFLGFHTLGLYVHNDVVVAFGTPEKQILIEPVFAQWIQAAHGKALYGFDVLLSNPDSIASTAWPNNGNVWLPGWLDAINSSTNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYAFPCDGPGRGGTCDISGWDSFYLSMFWMLNTIGWVTFYWHWKHLGIWQGNVAQFNESSTYLMGWLRDYLWLNSAQLINGYNPYGMNNLAVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLVWAHERTPLANLVRWKDKPVAMSIIQGRLIGLAHFTVGYILTYAAFLIASTASKFG
>NC_019693.1|WP_015151894.1|7464899_7467170_+|photosystem-I-core-protein-PsaA
MTISPPEREAKVKVTVDQDPVPTSFEKWAKPGHFDRTLSRGPKTTTWIWNLHANAHDFDSHTSDLEDVSRKIFSAHFGHLAVIFIWLSGAYFHGAKFSNYEAWLTDPTGIKPSAQVVWPIFGQEILNANVGGGFHGIQITSGLFQLWRASGITNEFQLYCTAIGALVMAALMLFAGWFHYHKRAPKLEWFQNVESMMNHHLAGLLGLGSLGWAGHQIHVSLPINKLLDSGVNAKDIPLPHEFILNPSLMTQLYPSVDWGFFKGVIPFFTLNWGVYSDFLTFKGGLNPVTGGLWLTDSAHHHVAIAVLFIIAGHMYRTNWGIGHSMKEMLEAHKGPFTGEGHKGLYEILTTSWHAQLAINLAMMGSLSIIVAHHMYSMPPYPYIATDYPTQLSLFTHHMWIGGFLIVGAGAHASIFMVRDYDPAKNVNNLLDRVLRHRDAIISHLNWVCMFLGFHSFGLYVHNDTMRAFGRPQDMFSDTGIQLQPIFAQWVQNLHFLAPGNTAPNALAPASFAFGGDVIAVGGKVAMMPITLGTADFLIHHIHAFTIHVTVLILLKGVLFARNSRLIPDKSELGFRFPCDGPGRGGTCQVSGWDHVFLGLFWMYNSLSIVIFHFSWKMQSDVWGTVSPDGSVAHITGGNFAQSAITINGWLRDFLWAQASQVIQSYGTALSAYGLLFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSIIQGRAVGVAHYLLGGIVTTWAFFLARIIAVSG
>NC_019693.1|WP_015151893.1|7462852_7464286_-|hypothetical-protein
MLGRNSRSPIVKSLLCAIAAIILLLGLGACSDRIEAPPNLEASQAVFIDSESQISEVSPPEEIQKLRLALDPYQPQVQILSPKPGEVLEDSTVAVQLQVRDLPLFKNQDLGLGPHLHLFLDHHPYQAIYDVREPIVLTDLEPGTHTLRVFASRPWHESFKNEGAYAQTTFHLFAPSEDNQPDPTKPLLTYSRPEGSYGAEPIMLDFYLTNAPLHLVAQENATDEIADWRIRVTINGDSFVLDRWDPIYLKGFKKGKNWVKVEFLDEKGNPVNNEFNTTVQAIDYQPKGKDTLSRLVRGDLKAEKAIVIVDPTYNPPPEPIAEPTPEPTPEPTPEPTPEPTPEPTPEPTPEPTPEPESLLPLPEPEEMPVELVPEEFMPMPETVAPAPTEESAELVPEEVQPELEVVEPAAQPVRRSRWDQLRDRLRRPTTEPATPVVPEPQAVPEVISQPSEIEALELTPPPDPTISEPEMTLEPIQ
>NC_019693.1|WP_015151892.1|7461937_7462672_-|Uma2-family-endonuclease
MVTTPQTTQVIYPDCDGNPMSDNTRQFRWIVVIKENLEILFDDDPNVFVAGDLLWYPIEGNNKLRQAPDVMVAIGRPKGDRGSYKQWEEGNIPPQVVFEILSPGNRLKEMVKKQQFYDRYGVEEYYIFDPDRLDFNGWLRNQAGSLELIEQPENWTSPRLGIRFELLDDQFTIYRPDGERFLTPTELAKQAEQQCQEAQQQRQEAEQQRQEAEQQRQRAESAEARLRELEARLRELEGDRHPEG
>NC_019693.1|WP_015151891.1|7461108_7461474_-|hypothetical-protein
MSEGKKQQFNAPVGSVDNQGIQHNVAGLNYGIQTTNTSDPELQATVQEIQTLMSSLDLTKATTTSEQMRLAGIVIAKIEEKPSFKERAINAARGGLLELLKQTPGGAFVAGAIEGWTKEKD
>NC_019693.1|WP_015151890.1|7460844_7461105_-|hypothetical-protein
MSEPTNQNTGSEGNQGHQANVAGVNKGIQNTNMITVNDASVNYGDHNTYNISGGRTPEQRKFDRDICRQMLEEQMQLTSNTVIGRV
>NC_019693.1|WP_015147345.1|7459676_7460789_-|IS630-family-transposase
MPAANCLTPEQVKKLQKSLKEEPNGEIRERILMLLLLNDGKTQAKIAQFIGCSINTVCHWCIHGNPDNLESLKDKRMEGNNKKATEEYVNLLLETLSKEPTELGYEFGRWTGHRLATYLHEITGIQLSGSQIRRILAKKKYVYIWGKYSLESKRDEEERKEFKKKLSEYLRIEKETPELLQVWFWDESGFSLRVIRRKNWCKKGKRKQIRGDRRNGRVNVMGGIRYSDKKRFVEFLKTSNSESFYNVLQVFYQELIQEWCDSGKSAHDFSEKGPKIIIILDNASFHKKAEFIQKIGENMPNIQLEFLPKYSPDYNLIELVWHSAKEYIAHRLFTSIEDLEVLLHKLLNEGELIIRWSRKLKNKGNAVIPI
>NC_019693.1|WP_015151899.1|7473046_7473271_+|DUF433-domain-containing-protein
MSKLLERITINPRQCGGRPCIRGMRIRVSDVLDLFAAGLSSEQILEELPDLEMDDLRATLAYASRKLNHPVLLA
>NC_019693.1|WP_015151900.1|7473323_7473545_-|DUF2281-domain-containing-protein
MSPLLEKVLAEVTQLDRQEQLQLVSYLVTRWQQQPQLFVEKKISRKKLFGCMRGKIKIAEDFDAPLNDFAEYM
>NC_019693.1|WP_015151901.1|7473729_7473933_+|hypothetical-protein
MLTTETELLAILRNLPQPALEEAKIFLDFLAWRYQNTSPKGANLIASLRGKATGEMTTDEILTLTRG
>NC_019693.1|WP_015151902.1|7474426_7474750_+|DUF4926-domain-containing-protein
MKPQHPLFSQVVLTGDLPQYHLKRGDIATIVEHYHHQESQEDGYSLEGFDVPQITIEVTASQIMPLSDYLKEEAILSKFRNLSEHQQKQLEEYLDFLLQKDQTTPVN
>NC_019693.1|WP_015151905.1|7478656_7478896_+|hypothetical-protein
MTAREKLIQAIQTLPESQVDQVLAYINQVRAEEGKIQEPDSQAKPCFDDIWWNNLSQFSTDFLEVREQPQLPVREDIFE
>NC_019693.1|WP_015151906.1|7478892_7479294_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MKFLLDTNICIYVIKQKPLRVKERLQKIDTGEVGLSIITLAELEYGAAKSQKPQGNREALTRFCLPFQIVDFSPEDAQNFGEIRANLERRGQPIGSYDLLIASQSVTRGLILVTNNIKEFSRVDGLNLENWVE
>NC_019693.1|WP_015151907.1|7479681_7480038_+|hypothetical-protein
MTDRIPSDFLQIIEDFLTLLEQAKTDPQTQPQLWTNLPSLETQLTAAEDKTLKLAKILKTWCKESQITFTPEELATIRANMIQKGEKIPKPAEGERPENVYNKPFLLQKVQEAKNTLA
>NC_019693.1|WP_015151908.1|7480067_7481498_+|hypothetical-protein
MSPKIASIYAPSLYWFAYQYHRGFVTSSDGTTAQTLEGINPQWVANRYHRILKKFEVELELEFRQDEPAQDFDLLMGPDDERAIVQLTTPQDLEGFIYPQSLHDSYALNLNIYQPESRGKEEYKIEDLAQFNPGNCFKPEPESASNLGQTLLLSGYVETTPPAKIRDLEPLAKECWIKFFHLENGQALPPLYRAYNLFGGYLYEYGSPKANLDKNPYGHLLIWLLFEEYPTLTLQNCYWELPELFLYYHKISKSFQESRIYYDCADRLITNHETEFTPVSQTYLNRQNKDLLSARELQVLKITLKTLLETSLNYTKQLRNLEYACNSIAINRKNYQSSLEQMEQLAQTPMEGLRLFHDKEAIAFQEQIRADLNYFYPGSNLLNQSIATIRGLVEIDQAERDRHLEHQIQTIGTAIAFGAIVASTSALLFEQSMTFPWQEPHGDRIHPFILAVFLSIVAAAFAWGVAGFIRWVWNRR
>NC_019693.1|WP_015151909.1|7481665_7482838_-|GNAT-family-N-acetyltransferase
MKHQREFGPLSNGKEAENLGLMLCHSFNFTGWELFRDRLGIKNYRALWQDNQIIGGLGLYPMAQWWGGNPVTMAGIAAVGVAPEHRGTGVADELLRHTLQELYDNQIPLSVLYPATQVLYRKVGYEQAGSLCKWQLPIQSIRMRDRTLTMHPIEPILSETIAALYQQQAVTCNGNLDRHPGIWENIFKPIPEETLYADLIGEPDDWQGYIIYSQQREGNSQTLAIADWVALTPAAIRRLWTFIADFRSQFANVIWRSSPVDPFLLTLPEQTGQMTEFSHWMLRIVDVPLSLQQRGYPSGIEAELHIKVQDNILSENNGKFILTVSNGKGEVTPGGRGDLRLEVRGLAPLYTGFFTPHQLHLSGHLQGNPSALSVATQLFSGPHPWMADMF
>NC_019693.1|WP_015151910.1|7483444_7484521_+|glycosyltransferase-family-4-protein
MRIAQVSPLAERVPPPGYGGIELVVSHLTDELVRRGHDVTLFASGDSETLAKLESVVPRALRLDPTVKEPAVYDMLQLNRIYEMASEFDIIHFHNGYSSLPLAELMKTSVVHTLHGNFSADSRKLYQKYGNQGYVSITNAQRDGGPELNYLDTVYNGIDIEAYPFFPKPQDPPYLAFLGRISPEKGIHHAIAIAKATGWHLKIAGKVDPVDQKFYENEIKPQIDGTQIEYLGETNHQQKVDVIGNAVATLFPITWREPFGLVMIESMCTGTPLIAMNLGSVPEVIAHGKTGIVCNSIEEMIAAIPAVEKLDRQACRDRVVSQFSIAKMVDGYEAAYRLALSKTIHQNGHIKDKLTVIA

Crispr_ID: NC_019693_80

• CRISPR_ID: NC_019693_80
• CRISPR_location: 7504261-7509286
• CRISPR_type: TypeI-D
• Repeat_type: N:A
• Spacer_info: 69 spacers
• Cas_protein_info: cas2,cas1,cas4,cas6,cas3,csc1gr5,csc2gr7,cas10d,WYL

Consensus repeat of NC_019693_80

Consensus_repeat	Method
GTTTCAATCC--------------------CTGAAAGGGATTAGAGGTCATTGGGAC	PILER-CR
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CRISPRCasFinder
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CRT

spacers of NC_019693_80

>80.1|7504298|38|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AAAACTTCTTTTAGAGGCATTCTATTCCCCTCTTTTCG
>80.2|7504373|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GAAGCCGCTTACGCTTTTATAGCTCAGTAATCCAAAG
>80.3|7504447|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TGATTGTCAAGACTCGGACTTTTTCCATATCCTC
>80.4|7504518|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTCAAACAGCAGACTTTCGGTTTCGCGACAGTGAGGA
>80.5|7504592|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTTCAAATCTGGGGTGTTTGTCAGCAAGAACTAC
>80.6|7504663|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CTAAAGGAACTACCGCCCAAACAACGGATCTTTCAAA
>80.7|7504737|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TGAGCACCGTATCTGATCCAAATAAAAAAATCCCCGA
>80.8|7504811|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CGTTTTCCCCCCCAACCCCCAAAGGGGGGGCCGGAA
>80.9|7504884|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AACAATCAACCCAACATCTCCTAGACTAGGAAAA
>80.10|7504955|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTTGGATCCAAGCCTTGCGGCATTGAAATTCAAC
>80.11|7505026|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CTGAAAGCTAAACTATCAGCACAAAACAAGCGATCGC
>80.12|7505100|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CGGTTTCGGTGTCTGGTGTTACCGGCAATTATGCG
>80.13|7505172|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CTGATGGCTCTGAGGGCGCAAGTATTCCCTATGCT
>80.14|7505244|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CACTAATTGTATAATCTATACCATCTGGTCTTAGAC
>80.15|7505317|40|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTGCATTGGCGTACACCTTGCAATTATCTAATTTGAACCC
>80.16|7505394|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CGATACAATGATTGCGGATCAGTTACTCACCTGCGG
>80.17|7505467|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TAAGAAGGGTTACGCCCCTGGGTGGGCGTTTGTGA
>80.18|7505539|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CTAATGCAGCGCCTCCTAAGGGCAGCTTATGGGGA
>80.19|7505611|33|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TAACTAACCCAGCCCATTTAGTGGATAGGTTAC
>80.20|7505681|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AAACACGCTGAGGCGATCGCTAAAGCGTTTAATGA
>80.21|7505753|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ACCCAATGGGAAAAACTTCCAGGTTTTGTAAAGCTC
>80.22|7505826|33|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GAAACACACTTCAAGGTAACATCACAGCATAAG
>80.23|7505896|33|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ATAGTAACCCTTAAGAGGATGATTCCACCTTTG
>80.24|7505966|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TCCCTGGGCAAGTTTTAGCACCGGCAACTATTTGTC
>80.25|7506039|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ATCTGCGGCTAACGCGGGTATTTCCGCTTGCGCCAAA
>80.26|7506113|33|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTTCCAAATACTTGATTCTTGACTTAGCTATTT
>80.27|7506183|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GAGCGAGATTTTACCGCTTCCCTGGAGCGCCAAAA
>80.28|7506255|41|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ATAAGTAAAACCACAAACATGAAGGTAAACATAGTCGGAGA
>80.29|7506333|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTTGACCAAAAATGCCAAGCCGAACAAATAGCAA
>80.30|7506404|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CCAGTTTTTTCTCTCCAGCTTCCCGCGCCTTATG
>80.31|7506475|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GCGGCTCCGGCTTCTTCCCCGGGTTTTCTCTCGGGGC
>80.32|7506549|33|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AAAATCAAGGTTGCAAAGCCTTAACTTTAGAAT
>80.33|7506619|41|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TCAGTATCAAGACCACTAGCAGTAGCCAGAAGCGCCAACTC
>80.34|7506697|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AATTCTTGGTCATCGCGAGAAATAGGAATTGAAAG
>80.35|7506769|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTGTAAACATTTGTGACAATCCCTTGCTTTTACTTG
>80.36|7506842|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CCGCTCTGAGACTTGGAAGGAAAATTTAGGGAAAG
>80.37|7506914|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CATCTCGTCCAGGGGACTGAACTGATCAAGCTGG
>80.38|7506985|33|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ATGGGAAAGTGACGCTTTCCAAACCGGCTACGG
>80.39|7507055|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TGTCTGCACAAGCTCCTTTTCCAAGAGGCTAATTT
>80.40|7507127|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ACGAAACCTCAAACGACTCCCCCGGCAACTGGAG
>80.41|7507198|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTGTGATGCCCTGCTGCAACGGACTTGTGGACTCGG
>80.42|7507271|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TGGGCGGTTGCAACAACGTTTAGGACTGACTTGA
>80.43|7507342|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CCACTGGCAACTCCACTTTCTATGCCATCTTGACT
>80.44|7507414|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ATATTAATGCTCCTGTTTGAGCTAAATTCTGTGGG
>80.45|7507486|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTTGATGCACTTCTGGAAAACCGCACCTACAGTGA
>80.46|7507558|32|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CAAAGCCTATGATTTGATTGCCGCTGCCAATG
>80.47|7507627|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TAACGGGTGTAAGGCTCCTAAAGGAACTTTCTGATGA
>80.48|7507701|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CTTCACCGTGCTGTCGTTAAGCTCTTTGTTCTTG
>80.49|7507772|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GACAAATCAAGGACCGACTTTTGGGAGGTGGTCA
>80.50|7507843|33|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTAAAGTCCCGAGCCAAACGTTTGATATCTTTC
>80.51|7507913|40|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CCACAAGGATTCGAGTAACCGAGAGTCTTCCATCCGGTCA
>80.52|7507990|33|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GCAGTTAAGGCAAACACCGCGCCACCGATGCTG
>80.53|7508060|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AAATACATAGGGGTGACTGCAACTGCTACAATAA
>80.54|7508131|33|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ACGGTATGATGGCTGGAGCGGGGATGATAATAG
>80.55|7508201|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ATAGGTCTACTGCGTTTTGCCATAAAGTCCACAA
>80.56|7508272|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AACGGTGAGGTAGAAGACTACTATTTTAATTCCAAAA
>80.57|7508346|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TGGCATATATTTCAACGCCATAAAGTCCGGCAACT
>80.58|7508418|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ACGCCGTAAATGCTGATTGGGGTAAAAATTTCCTCA
>80.59|7508491|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GCAAATACAGGTATCCCACTGATGTCCCCCCAAGG
>80.60|7508563|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTTGACAGCCCAATGCGCCTAATTTCAGCCGATA
>80.61|7508634|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TAGCCTACTGTGAAACTTACGATAATCGGTTTATC
>80.62|7508706|38|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AAATGAATGGTATGGGCATTGCGCCAAATACATATCAA
>80.63|7508781|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
ACTCAGGGATAAATCGGATATTGCCCATTTTCCA
>80.64|7508852|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CACCTAATCTCCTAAATTTGGCTGACACAATTACC
>80.65|7508924|33|NC_019693|PILER-CR,CRISPRCasFinder,CRT
TTTGACTCGTTACGTTCGCCCCGCTGAGGTGGA
>80.66|7508994|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT
AACAGGGTTAATCTCGTCCTGTTCTGTCTCGGAA
>80.67|7509065|33|NC_019693|PILER-CR,CRISPRCasFinder,CRT
CCAGGAATGGAAAGCAGGGATTCTCCGGCAATG
>80.68|7509135|41|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GGTCCCCAAACCCTCTCCCCGAGAGCGATTCATCAGTTACC
>80.69|7509213|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT
GTCGTTAGCCAACACCAACACAGTCCCATCAGTATTT

CRISPR arrays and Neighbor proteins around NC_019693_80

CRISPR arrays

The CRISPR arrays of NC_019693_80

>merge|NC_019693|80|7504261-7509286|PILER-CR,CRISPRCasFinder,CRT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAAAACTTCTTTTAGAGGCATTCTATTCCCCTCTTTTCGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGAAGCCGCTTACGCTTTTATAGCTCAGTAATCCAAAGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTGATTGTCAAGACTCGGACTTTTTCCATATCCTCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTTCAAACAGCAGACTTTCGGTTTCGCGACAGTGAGGAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTTTCAAATCTGGGGTGTTTGTCAGCAAGAACTACGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCTAAAGGAACTACCGCCCAAACAACGGATCTTTCAAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTGAGCACCGTATCTGATCCAAATAAAAAAATCCCCGAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCGTTTTCCCCCCCAACCCCCAAAGGGGGGGCCGGAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAACAATCAACCCAACATCTCCTAGACTAGGAAAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTTTGGATCCAAGCCTTGCGGCATTGAAATTCAACGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCTGAAAGCTAAACTATCAGCACAAAACAAGCGATCGCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCGGTTTCGGTGTCTGGTGTTACCGGCAATTATGCGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCTGATGGCTCTGAGGGCGCAAGTATTCCCTATGCTGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCACTAATTGTATAATCTATACCATCTGGTCTTAGACGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTTGCATTGGCGTACACCTTGCAATTATCTAATTTGAACCCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCGATACAATGATTGCGGATCAGTTACTCACCTGCGGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTAAGAAGGGTTACGCCCCTGGGTGGGCGTTTGTGAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCTAATGCAGCGCCTCCTAAGGGCAGCTTATGGGGAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTAACTAACCCAGCCCATTTAGTGGATAGGTTACGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAAACACGCTGAGGCGATCGCTAAAGCGTTTAATGAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACACCCAATGGGAAAAACTTCCAGGTTTTGTAAAGCTCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGAAACACACTTCAAGGTAACATCACAGCATAAGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACATAGTAACCCTTAAGAGGATGATTCCACCTTTGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTCCCTGGGCAAGTTTTAGCACCGGCAACTATTTGTCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACATCTGCGGCTAACGCGGGTATTTCCGCTTGCGCCAAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTTTCCAAATACTTGATTCTTGACTTAGCTATTTGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGAGCGAGATTTTACCGCTTCCCTGGAGCGCCAAAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACATAAGTAAAACCACAAACATGAAGGTAAACATAGTCGGAGAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTTTGACCAAAAATGCCAAGCCGAACAAATAGCAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCCAGTTTTTTCTCTCCAGCTTCCCGCGCCTTATGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGCGGCTCCGGCTTCTTCCCCGGGTTTTCTCTCGGGGCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAAAATCAAGGTTGCAAAGCCTTAACTTTAGAATGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTCAGTATCAAGACCACTAGCAGTAGCCAGAAGCGCCAACTCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAATTCTTGGTCATCGCGAGAAATAGGAATTGAAAGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTTGTAAACATTTGTGACAATCCCTTGCTTTTACTTGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCCGCTCTGAGACTTGGAAGGAAAATTTAGGGAAAGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCATCTCGTCCAGGGGACTGAACTGATCAAGCTGGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACATGGGAAAGTGACGCTTTCCAAACCGGCTACGGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTGTCTGCACAAGCTCCTTTTCCAAGAGGCTAATTTGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACACGAAACCTCAAACGACTCCCCCGGCAACTGGAGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTTGTGATGCCCTGCTGCAACGGACTTGTGGACTCGGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTGGGCGGTTGCAACAACGTTTAGGACTGACTTGAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCCACTGGCAACTCCACTTTCTATGCCATCTTGACTGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACATATTAATGCTCCTGTTTGAGCTAAATTCTGTGGGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTTTGATGCACTTCTGGAAAACCGCACCTACAGTGAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCAAAGCCTATGATTTGATTGCCGCTGCCAATGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTAACGGGTGTAAGGCTCCTAAAGGAACTTTCTGATGAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCTTCACCGTGCTGTCGTTAAGCTCTTTGTTCTTGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGACAAATCAAGGACCGACTTTTGGGAGGTGGTCAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTTAAAGTCCCGAGCCAAACGTTTGATATCTTTCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCCACAAGGATTCGAGTAACCGAGAGTCTTCCATCCGGTCAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGCAGTTAAGGCAAACACCGCGCCACCGATGCTGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAAATACATAGGGGTGACTGCAACTGCTACAATAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACACGGTATGATGGCTGGAGCGGGGATGATAATAGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACATAGGTCTACTGCGTTTTGCCATAAAGTCCACAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAACGGTGAGGTAGAAGACTACTATTTTAATTCCAAAAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTGGCATATATTTCAACGCCATAAAGTCCGGCAACTGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACACGCCGTAAATGCTGATTGGGGTAAAAATTTCCTCAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACGCAAATACAGGTATCCCACTGATGTCCCCCCAAGGGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTTTGACAGCCCAATGCGCCTAATTTCAGCCGATAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTAGCCTACTGTGAAACTTACGATAATCGGTTTATCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACAAATGAATGGTATGGGCATTGCGCCAAATACATATCAAGTCTCAATGACCTCTAATCCCTTTCAGGGATTGAAACACTCAGGGATAAATCGGATATTGCCCATTTTCCAGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACCACCTAATCTCCTAAATTTGGCTGACACAATTACCGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAACTTTGACTCGTTACGTTCGCCCCGCTGAGGTGGAGTCCCAATGACCCTAAATCCCTTTCAGGGATTGAAACAACAGGGTTAATCTCGTCCTGTTCTGTCTCGGAAGTCCCAATGACCCTAAATCCCTTTCAGGGATTGAAACCCAGGAATGGAAAGCAGGGATTCTCCGGCAATGGTCCCAATGACCCTAAATCCCTTTCAGGGATTGAAACGGTCCCCAAACCCTCTCCCCGAGAGCGATTCATCAGTTACCGTCCCAATGACCCTAAATCCCTTTCAGGGATTGAAACGTCGTTAGCCAACACCAACACAGTCCCATCAGTATTTGTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC

>NC_019693|80|11|7504261-7509286|PILER-CR
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAAACTTCTTTTAGAGGCATTCTATTCCCCTCTTTTCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAAGCCGCTTACGCTTTTATAGCTCAGTAATCCAAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGATTGTCAAGACTCGGACTTTTTCCATATCCTC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTCAAACAGCAGACTTTCGGTTTCGCGACAGTGAGGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTCAAATCTGGGGTGTTTGTCAGCAAGAACTAC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTAAAGGAACTACCGCCCAAACAACGGATCTTTCAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGAGCACCGTATCTGATCCAAATAAAAAAATCCCCGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CGTTTTCCCCCCCAACCCCCAAAGGGGGGGCCGGAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AACAATCAACCCAACATCTCCTAGACTAGGAAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGGATCCAAGCCTTGCGGCATTGAAATTCAAC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTGAAAGCTAAACTATCAGCACAAAACAAGCGATCGC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CGGTTTCGGTGTCTGGTGTTACCGGCAATTATGCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTGATGGCTCTGAGGGCGCAAGTATTCCCTATGCT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CACTAATTGTATAATCTATACCATCTGGTCTTAGAC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGCATTGGCGTACACCTTGCAATTATCTAATTTGAACCC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CGATACAATGATTGCGGATCAGTTACTCACCTGCGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAAGAAGGGTTACGCCCCTGGGTGGGCGTTTGTGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTAATGCAGCGCCTCCTAAGGGCAGCTTATGGGGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAACTAACCCAGCCCATTTAGTGGATAGGTTAC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAACACGCTGAGGCGATCGCTAAAGCGTTTAATGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACCCAATGGGAAAAACTTCCAGGTTTTGTAAAGCTC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAAACACACTTCAAGGTAACATCACAGCATAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATAGTAACCCTTAAGAGGATGATTCCACCTTTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TCCCTGGGCAAGTTTTAGCACCGGCAACTATTTGTC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATCTGCGGCTAACGCGGGTATTTCCGCTTGCGCCAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTCCAAATACTTGATTCTTGACTTAGCTATTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAGCGAGATTTTACCGCTTCCCTGGAGCGCCAAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATAAGTAAAACCACAAACATGAAGGTAAACATAGTCGGAGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGACCAAAAATGCCAAGCCGAACAAATAGCAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCAGTTTTTTCTCTCCAGCTTCCCGCGCCTTATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCGGCTCCGGCTTCTTCCCCGGGTTTTCTCTCGGGGC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAAATCAAGGTTGCAAAGCCTTAACTTTAGAAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TCAGTATCAAGACCACTAGCAGTAGCCAGAAGCGCCAACTC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AATTCTTGGTCATCGCGAGAAATAGGAATTGAAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGTAAACATTTGTGACAATCCCTTGCTTTTACTTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCGCTCTGAGACTTGGAAGGAAAATTTAGGGAAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CATCTCGTCCAGGGGACTGAACTGATCAAGCTGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATGGGAAAGTGACGCTTTCCAAACCGGCTACGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGTCTGCACAAGCTCCTTTTCCAAGAGGCTAATTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACGAAACCTCAAACGACTCCCCCGGCAACTGGAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGTGATGCCCTGCTGCAACGGACTTGTGGACTCGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGGGCGGTTGCAACAACGTTTAGGACTGACTTGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCACTGGCAACTCCACTTTCTATGCCATCTTGACT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATATTAATGCTCCTGTTTGAGCTAAATTCTGTGGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGATGCACTTCTGGAAAACCGCACCTACAGTGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CAAAGCCTATGATTTGATTGCCGCTGCCAATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAACGGGTGTAAGGCTCCTAAAGGAACTTTCTGATGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTTCACCGTGCTGTCGTTAAGCTCTTTGTTCTTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GACAAATCAAGGACCGACTTTTGGGAGGTGGTCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTAAAGTCCCGAGCCAAACGTTTGATATCTTTC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCACAAGGATTCGAGTAACCGAGAGTCTTCCATCCGGTCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCAGTTAAGGCAAACACCGCGCCACCGATGCTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAATACATAGGGGTGACTGCAACTGCTACAATAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACGGTATGATGGCTGGAGCGGGGATGATAATAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATAGGTCTACTGCGTTTTGCCATAAAGTCCACAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AACGGTGAGGTAGAAGACTACTATTTTAATTCCAAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGGCATATATTTCAACGCCATAAAGTCCGGCAACT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACGCCGTAAATGCTGATTGGGGTAAAAATTTCCTCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCAAATACAGGTATCCCACTGATGTCCCCCCAAGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGACAGCCCAATGCGCCTAATTTCAGCCGATA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAGCCTACTGTGAAACTTACGATAATCGGTTTATC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAATGAATGGTATGGGCATTGCGCCAAATACATATCAA
GTCTCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACTCAGGGATAAATCGGATATTGCCCATTTTCCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CACCTAATCTCCTAAATTTGGCTGACACAATTACC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGACTCGTTACGTTCGCCCCGCTGAGGTGGA
GTCCCAATGACCCTAAATCCCTTTCAGGGATTGAAAC	AACAGGGTTAATCTCGTCCTGTTCTGTCTCGGAA
GTCCCAATGACCCTAAATCCCTTTCAGGGATTGAAAC	CCAGGAATGGAAAGCAGGGATTCTCCGGCAATG
GTCCCAATGACCCTAAATCCCTTTCAGGGATTGAAAC	GGTCCCCAAACCCTCTCCCCGAGAGCGATTCATCAGTTACC
GTCCCAATGACCCTAAATCCCTTTCAGGGATTGAAAC	GTCGTTAGCCAACACCAACACAGTCCCATCAGTATTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC

>NC_019693|80|78|7504261-7509286|CRISPRCasFinder
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAAACTTCTTTTAGAGGCATTCTATTCCCCTCTTTTCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAAGCCGCTTACGCTTTTATAGCTCAGTAATCCAAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGATTGTCAAGACTCGGACTTTTTCCATATCCTC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTCAAACAGCAGACTTTCGGTTTCGCGACAGTGAGGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTCAAATCTGGGGTGTTTGTCAGCAAGAACTAC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTAAAGGAACTACCGCCCAAACAACGGATCTTTCAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGAGCACCGTATCTGATCCAAATAAAAAAATCCCCGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CGTTTTCCCCCCCAACCCCCAAAGGGGGGGCCGGAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AACAATCAACCCAACATCTCCTAGACTAGGAAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGGATCCAAGCCTTGCGGCATTGAAATTCAAC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTGAAAGCTAAACTATCAGCACAAAACAAGCGATCGC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CGGTTTCGGTGTCTGGTGTTACCGGCAATTATGCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTGATGGCTCTGAGGGCGCAAGTATTCCCTATGCT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CACTAATTGTATAATCTATACCATCTGGTCTTAGAC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGCATTGGCGTACACCTTGCAATTATCTAATTTGAACCC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CGATACAATGATTGCGGATCAGTTACTCACCTGCGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAAGAAGGGTTACGCCCCTGGGTGGGCGTTTGTGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTAATGCAGCGCCTCCTAAGGGCAGCTTATGGGGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAACTAACCCAGCCCATTTAGTGGATAGGTTAC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAACACGCTGAGGCGATCGCTAAAGCGTTTAATGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACCCAATGGGAAAAACTTCCAGGTTTTGTAAAGCTC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAAACACACTTCAAGGTAACATCACAGCATAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATAGTAACCCTTAAGAGGATGATTCCACCTTTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TCCCTGGGCAAGTTTTAGCACCGGCAACTATTTGTC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATCTGCGGCTAACGCGGGTATTTCCGCTTGCGCCAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTCCAAATACTTGATTCTTGACTTAGCTATTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAGCGAGATTTTACCGCTTCCCTGGAGCGCCAAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATAAGTAAAACCACAAACATGAAGGTAAACATAGTCGGAGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGACCAAAAATGCCAAGCCGAACAAATAGCAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCAGTTTTTTCTCTCCAGCTTCCCGCGCCTTATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCGGCTCCGGCTTCTTCCCCGGGTTTTCTCTCGGGGC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAAATCAAGGTTGCAAAGCCTTAACTTTAGAAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TCAGTATCAAGACCACTAGCAGTAGCCAGAAGCGCCAACTC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AATTCTTGGTCATCGCGAGAAATAGGAATTGAAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGTAAACATTTGTGACAATCCCTTGCTTTTACTTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCGCTCTGAGACTTGGAAGGAAAATTTAGGGAAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CATCTCGTCCAGGGGACTGAACTGATCAAGCTGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATGGGAAAGTGACGCTTTCCAAACCGGCTACGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGTCTGCACAAGCTCCTTTTCCAAGAGGCTAATTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACGAAACCTCAAACGACTCCCCCGGCAACTGGAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGTGATGCCCTGCTGCAACGGACTTGTGGACTCGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGGGCGGTTGCAACAACGTTTAGGACTGACTTGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCACTGGCAACTCCACTTTCTATGCCATCTTGACT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATATTAATGCTCCTGTTTGAGCTAAATTCTGTGGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGATGCACTTCTGGAAAACCGCACCTACAGTGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CAAAGCCTATGATTTGATTGCCGCTGCCAATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAACGGGTGTAAGGCTCCTAAAGGAACTTTCTGATGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTTCACCGTGCTGTCGTTAAGCTCTTTGTTCTTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GACAAATCAAGGACCGACTTTTGGGAGGTGGTCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTAAAGTCCCGAGCCAAACGTTTGATATCTTTC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCACAAGGATTCGAGTAACCGAGAGTCTTCCATCCGGTCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCAGTTAAGGCAAACACCGCGCCACCGATGCTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAATACATAGGGGTGACTGCAACTGCTACAATAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACGGTATGATGGCTGGAGCGGGGATGATAATAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATAGGTCTACTGCGTTTTGCCATAAAGTCCACAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AACGGTGAGGTAGAAGACTACTATTTTAATTCCAAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGGCATATATTTCAACGCCATAAAGTCCGGCAACT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACGCCGTAAATGCTGATTGGGGTAAAAATTTCCTCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCAAATACAGGTATCCCACTGATGTCCCCCCAAGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGACAGCCCAATGCGCCTAATTTCAGCCGATA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAGCCTACTGTGAAACTTACGATAATCGGTTTATC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAATGAATGGTATGGGCATTGCGCCAAATACATATCAA
GTCTCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACTCAGGGATAAATCGGATATTGCCCATTTTCCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CACCTAATCTCCTAAATTTGGCTGACACAATTACC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGACTCGTTACGTTCGCCCCGCTGAGGTGGA
GTCCCAATGACCCTAAATCCCTTTCAGGGATTGAAAC	AACAGGGTTAATCTCGTCCTGTTCTGTCTCGGAA
GTCCCAATGACCCTAAATCCCTTTCAGGGATTGAAAC	CCAGGAATGGAAAGCAGGGATTCTCCGGCAATG
GTCCCAATGACCCTAAATCCCTTTCAGGGATTGAAAC	GGTCCCCAAACCCTCTCCCCGAGAGCGATTCATCAGTTACC
GTCCCAATGACCCTAAATCCCTTTCAGGGATTGAAAC	GTCGTTAGCCAACACCAACACAGTCCCATCAGTATTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC

>NC_019693|80|9|7504261-7509286|CRT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAAACTTCTTTTAGAGGCATTCTATTCCCCTCTTTTCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAAGCCGCTTACGCTTTTATAGCTCAGTAATCCAAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGATTGTCAAGACTCGGACTTTTTCCATATCCTC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTCAAACAGCAGACTTTCGGTTTCGCGACAGTGAGGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTCAAATCTGGGGTGTTTGTCAGCAAGAACTAC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTAAAGGAACTACCGCCCAAACAACGGATCTTTCAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGAGCACCGTATCTGATCCAAATAAAAAAATCCCCGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CGTTTTCCCCCCCAACCCCCAAAGGGGGGGCCGGAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AACAATCAACCCAACATCTCCTAGACTAGGAAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGGATCCAAGCCTTGCGGCATTGAAATTCAAC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTGAAAGCTAAACTATCAGCACAAAACAAGCGATCGC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CGGTTTCGGTGTCTGGTGTTACCGGCAATTATGCG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTGATGGCTCTGAGGGCGCAAGTATTCCCTATGCT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CACTAATTGTATAATCTATACCATCTGGTCTTAGAC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGCATTGGCGTACACCTTGCAATTATCTAATTTGAACCC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CGATACAATGATTGCGGATCAGTTACTCACCTGCGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAAGAAGGGTTACGCCCCTGGGTGGGCGTTTGTGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTAATGCAGCGCCTCCTAAGGGCAGCTTATGGGGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAACTAACCCAGCCCATTTAGTGGATAGGTTAC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAACACGCTGAGGCGATCGCTAAAGCGTTTAATGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACCCAATGGGAAAAACTTCCAGGTTTTGTAAAGCTC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAAACACACTTCAAGGTAACATCACAGCATAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATAGTAACCCTTAAGAGGATGATTCCACCTTTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TCCCTGGGCAAGTTTTAGCACCGGCAACTATTTGTC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATCTGCGGCTAACGCGGGTATTTCCGCTTGCGCCAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTCCAAATACTTGATTCTTGACTTAGCTATTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GAGCGAGATTTTACCGCTTCCCTGGAGCGCCAAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATAAGTAAAACCACAAACATGAAGGTAAACATAGTCGGAGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGACCAAAAATGCCAAGCCGAACAAATAGCAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCAGTTTTTTCTCTCCAGCTTCCCGCGCCTTATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCGGCTCCGGCTTCTTCCCCGGGTTTTCTCTCGGGGC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAAATCAAGGTTGCAAAGCCTTAACTTTAGAAT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TCAGTATCAAGACCACTAGCAGTAGCCAGAAGCGCCAACTC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AATTCTTGGTCATCGCGAGAAATAGGAATTGAAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGTAAACATTTGTGACAATCCCTTGCTTTTACTTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCGCTCTGAGACTTGGAAGGAAAATTTAGGGAAAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CATCTCGTCCAGGGGACTGAACTGATCAAGCTGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATGGGAAAGTGACGCTTTCCAAACCGGCTACGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGTCTGCACAAGCTCCTTTTCCAAGAGGCTAATTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACGAAACCTCAAACGACTCCCCCGGCAACTGGAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTGTGATGCCCTGCTGCAACGGACTTGTGGACTCGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGGGCGGTTGCAACAACGTTTAGGACTGACTTGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCACTGGCAACTCCACTTTCTATGCCATCTTGACT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATATTAATGCTCCTGTTTGAGCTAAATTCTGTGGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGATGCACTTCTGGAAAACCGCACCTACAGTGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CAAAGCCTATGATTTGATTGCCGCTGCCAATG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAACGGGTGTAAGGCTCCTAAAGGAACTTTCTGATGA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CTTCACCGTGCTGTCGTTAAGCTCTTTGTTCTTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GACAAATCAAGGACCGACTTTTGGGAGGTGGTCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTAAAGTCCCGAGCCAAACGTTTGATATCTTTC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CCACAAGGATTCGAGTAACCGAGAGTCTTCCATCCGGTCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCAGTTAAGGCAAACACCGCGCCACCGATGCTG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAATACATAGGGGTGACTGCAACTGCTACAATAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACGGTATGATGGCTGGAGCGGGGATGATAATAG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ATAGGTCTACTGCGTTTTGCCATAAAGTCCACAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AACGGTGAGGTAGAAGACTACTATTTTAATTCCAAAA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TGGCATATATTTCAACGCCATAAAGTCCGGCAACT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACGCCGTAAATGCTGATTGGGGTAAAAATTTCCTCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	GCAAATACAGGTATCCCACTGATGTCCCCCCAAGG
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGACAGCCCAATGCGCCTAATTTCAGCCGATA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TAGCCTACTGTGAAACTTACGATAATCGGTTTATC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	AAATGAATGGTATGGGCATTGCGCCAAATACATATCAA
GTCTCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	ACTCAGGGATAAATCGGATATTGCCCATTTTCCA
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	CACCTAATCTCCTAAATTTGGCTGACACAATTACC
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC	TTTGACTCGTTACGTTCGCCCCGCTGAGGTGGA
GTCCCAATGACCCTAAATCCCTTTCAGGGATTGAAAC	AACAGGGTTAATCTCGTCCTGTTCTGTCTCGGAA
GTCCCAATGACCCTAAATCCCTTTCAGGGATTGAAAC	CCAGGAATGGAAAGCAGGGATTCTCCGGCAATG
GTCCCAATGACCCTAAATCCCTTTCAGGGATTGAAAC	GGTCCCCAAACCCTCTCCCCGAGAGCGATTCATCAGTTACC
GTCCCAATGACCCTAAATCCCTTTCAGGGATTGAAAC	GTCGTTAGCCAACACCAACACAGTCCCATCAGTATTT
GTCCCAATGACCTCTAATCCCTTTCAGGGATTGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015151925.1|7501831_7502425_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|187768
NC_019693.1|WP_015151918.1|7492475_7493342_-|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl|CDD|225253
NC_019693.1|WP_015151923.1|7500403_7500649_+|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151928.1|7509380_7509923_-|DUF2231-domain-containing-protein	unknown	unknown	gnl|CDD|226695
NC_019693.1|WP_015151922.1|7498116_7500372_+|type-I-D-CRISPR-associated-helicase-Cas3'	cas3	cd09710_cas3_CAS-I-D	gnl|CDD|187841
NC_019693.1|WP_015151926.1|7502642_7503647_+|type-I-D-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|274976
NC_019693.1|WP_156824122.1|7526534_7527281_+|cobalt-precorrin-6A-reductase	unknown	unknown	gnl|CDD|236144
NC_019693.1|WP_015151932.1|7514803_7515193_-|Nuclease-A-inhibitor-like-protein	unknown	unknown	gnl|CDD|369598
NC_019693.1|WP_015151937.1|7523502_7526022_+|phosphoenolpyruvate-synthase	unknown	unknown	gnl|CDD|235809
NC_019693.1|WP_015151927.1|7503731_7504004_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NC_019693.1|WP_015151919.1|7493416_7496137_+|hypothetical-protein	cas10d	mkCas0201_cas10d_CAS-I-D	unknown
NC_019693.1|WP_015151936.1|7521258_7522683_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_019693.1|WP_015151930.1|7512052_7513489_-|folate/biopterin-family-MFS-transporter	unknown	unknown	gnl|CDD|341037
NC_019693.1|WP_015151933.1|7515341_7516952_-|Hsp70-family-protein	unknown	unknown	gnl|CDD|212667
NC_019693.1|WP_015151929.1|7510091_7511588_-|lignostilbene-alpha,beta-dioxygenase-like-protein	unknown	unknown	gnl|CDD|226196
NC_019693.1|WP_015151920.1|7496148_7497174_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	gnl|CDD|375747
NC_019693.1|WP_015151924.1|7500754_7501582_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl|CDD|227838
NC_019693.1|WP_083896837.1|7517031_7519053_-|hypothetical-protein	unknown	unknown	gnl|CDD|224276
NC_019693.1|WP_015151931.1|7513665_7514499_+|DNA/RNA-non-specific-endonuclease	unknown	unknown	gnl|CDD|224777
NC_019693.1|WP_015151921.1|7497331_7498120_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	gnl|CDD|274458

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019693.1|WP_015151927.1|7503731_7504004_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5e-30	98.5	0.8
NC_019693.1|WP_015151925.1|7501831_7502425_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	1.2e-52	173.3	1.3
NC_019693.1|WP_015151918.1|7492475_7493342_-|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	8.3e-18	59.7	2.6
NC_019693.1|WP_015151919.1|7493416_7496137_+|hypothetical-protein	cas10d	mkCas0201_cas10d_CAS-I-D	0	1255.2	0.0
NC_019693.1|WP_015151922.1|7498116_7500372_+|type-I-D-CRISPR-associated-helicase-Cas3'	cas3	cd09710_cas3_CAS-I-D	2.4e-108	357.0	0.0
NC_019693.1|WP_015151926.1|7502642_7503647_+|type-I-D-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	2.2e-103	340.3	0.0
NC_019693.1|WP_015151920.1|7496148_7497174_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	4.1e-93	306.4	0.0
NC_019693.1|WP_015151921.1|7497331_7498120_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	9.1e-56	183.4	0.0
NC_019693.1|WP_015151924.1|7500754_7501582_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	3.2e-49	162.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015151925.1|7501831_7502425_+|CRISPR-associated-protein-Cas4	gnl|CDD|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	1.37019e-58
NC_019693.1|WP_015151918.1|7492475_7493342_-|WYL-domain-containing-protein	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	2.0742e-14
NC_019693.1|WP_015151928.1|7509380_7509923_-|DUF2231-domain-containing-protein	gnl|CDD|226695	COG4244, COG4244, Predicted membrane protein [Function unknown].	5.51023e-33
NC_019693.1|WP_015151922.1|7498116_7500372_+|type-I-D-CRISPR-associated-helicase-Cas3'	gnl|CDD|187841	cd09710, Cas3_I-D, CRISPR/Cas system-associated protein Cas3; Distinct diverged subfamily of Cas3 helicase domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Diverged DNA helicase Cas3'; signature gene for Type I and subtype I-D.	2.06774e-110
NC_019693.1|WP_015151926.1|7502642_7503647_+|type-I-D-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274976	TIGR04093, hypothetical_protein_L8106_25395, CRISPR-associated endonuclease Cas1, subtype CYANO. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes a clade of Cas1 limited to the CYANO subtype of CRISPR/Cas system and most often the type found there.	3.36921e-152
NC_019693.1|WP_156824122.1|7526534_7527281_+|cobalt-precorrin-6A-reductase	gnl|CDD|236144	PRK08057, PRK08057, cobalt-precorrin-6x reductase; Reviewed.	4.27877e-109
NC_019693.1|WP_015151932.1|7514803_7515193_-|Nuclease-A-inhibitor-like-protein	gnl|CDD|369598	pfam07924, NuiA, Nuclease A inhibitor-like protein. This family consists of protein sequences that are similar to the nuclease A inhibitor expressed by bacteria of the genus Anabaena ((NuiA). This sequence is organized to form an alpha-beta-alpha sandwich fold, which is similar to the PR-1-like fold. NuiA interacts with nuclease A by means of residues located at one end of the molecule, including residues making up the loop between helices III and IV and the loop between strands C and D. The mechanism of inhibition of nuclease A by NuiA is as yet incompletely understood.	1.19596e-55
NC_019693.1|WP_015151937.1|7523502_7526022_+|phosphoenolpyruvate-synthase	gnl|CDD|235809	PRK06464, PRK06464, phosphoenolpyruvate synthase; Validated.	0
NC_019693.1|WP_015151927.1|7503731_7504004_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.18279e-34
NC_019693.1|WP_015151936.1|7521258_7522683_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.25975e-60
NC_019693.1|WP_015151930.1|7512052_7513489_-|folate/biopterin-family-MFS-transporter	gnl|CDD|341037	cd17484, MFS_FBT, Folate-biopterin transporter of the Major Facilitator Superfamily of transporters. The Folate-biopterin transporter (FBT) family includes folate carriers related to those of trypanosomatids in higher plant plastids and cyanobacteria. FBT mediates folate monoglutamate transport involved in tetrahydrofolate biosynthesis. It also mediates transport of antifolates, such as methotrexate and aminopterin. The FBT family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.49821e-176
NC_019693.1|WP_015151933.1|7515341_7516952_-|Hsp70-family-protein	gnl|CDD|212667	cd10170, HSP70_NBD, Nucleotide-binding domain of the HSP70 family. HSP70 (70-kDa heat shock protein) family chaperones assist in protein folding and assembly and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). Some HSP70 family members are not chaperones but instead, function as NEFs to remove ADP from their HSP70 chaperone partners during the ATP hydrolysis cycle, some may function as both chaperones and NEFs.	1.54366e-43
NC_019693.1|WP_015151929.1|7510091_7511588_-|lignostilbene-alpha,beta-dioxygenase-like-protein	gnl|CDD|226196	COG3670, COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	0
NC_019693.1|WP_015151920.1|7496148_7497174_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2	gnl|CDD|375747	pfam18320, Csc2, Csc2 Crispr. The Csc2 Crispr family of proteins forms a core RNA recognition motif-like domain, flanked by three peripheral insertion domains: a lid domain, a Zinc-binding domain and a helical domain. The CRISPR-Cas system is possibly a mechanism of defence against invading pathogens and plasmids that functions analogously to the RNA interference (RNAi) systems in eukaryotes.	3.06546e-170
NC_019693.1|WP_015151924.1|7500754_7501582_+|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.98373e-37
NC_019693.1|WP_083896837.1|7517031_7519053_-|hypothetical-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	8.99162e-34
NC_019693.1|WP_015151931.1|7513665_7514499_+|DNA/RNA-non-specific-endonuclease	gnl|CDD|224777	COG1864, NUC1, DNA/RNA endonuclease G, NUC1 [Nucleotide transport and metabolism].	8.38719e-82
NC_019693.1|WP_015151921.1|7497331_7498120_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1	gnl|CDD|274458	TIGR03159, cas_Csc1, CRISPR type I-D/CYANO-associated protein Csc1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family is a CRISPR-associated (Cas) family strictly associated with the Cyano subtype of CRISPR/Cas locus, found in several species of Cyanobacteria and several archaeal species. This family is designated Csc1 for CRISPR/Cas Subtype Cyano protein 1, as it is often the first gene upstream of the core cas genes, cas3-cas4-cas1-cas2.	2.78915e-65

Protein sequences

>NC_019693.1|WP_015151927.1|7503731_7504004_+|CRISPR-associated-endonuclease-Cas2
MYVVIAYDISEDKRRTKIHNILKSYGQWVQFSMFECDLNPTQYQRLRMRLSKQIKPDEDNIRFFFLCACCQGKIERIGGVEPRDSTIFFA
>NC_019693.1|WP_015151926.1|7502642_7503647_+|type-I-D-CRISPR-associated-endonuclease-Cas1
MGTVYITQDDCFIGKTDERLNIRVNKQKLLDVPLINIEGVVIMGRATVSPAVVTELLNRHIPLSFLTTTGRYLGRLEPELTKNIFVRKAQWQAAGETEKALHLVRGFIRGKLKNYRTALLRKQRQGSDVNFQTATDRLKQILSSLTSTATIDSLRGLEGAGSAAYFQCFDALIRSEGFSFEARRRRPPTDPVNALLSLGYSLLSHDIQSAVNIVGFDPYLGYLHVERYGRPSLALDLMEEFRPLVVDAMVLNAINNRIITPSDFTTEPISNAVSLTPEALRTFLRLYEQKKQSDFTHPVMGKKCTYQESFEIQGRLMAKYLMEEIDQYPPLVLK
>NC_019693.1|WP_015151925.1|7501831_7502425_+|CRISPR-associated-protein-Cas4
MNNSDYITIAALNQYAYCPHRCWRMFCAGEFRDNHYTLEGTDLHERVHTLGEGNREEVWQVRAIWLKSERYQLIGKADLIESVEGEVYPIEYKRGKKGEWDNDELQVCAQALCLEEMMGKTIERGYVYYAQTRRRQAVEITEELRQEAIATLEAISNLLQTGTMPPPIYTKRCRGCSLFNQCLPQAADKIKGYQEAS
>NC_019693.1|WP_015151924.1|7500754_7501582_+|CRISPR-associated-endoribonuclease-Cas6
MPHSLIINLVPTSPIYPQFLTGRHLHALFLTLINSVNPELATSLHEQKSEKAFTLSPLQVSHSSQNAGHLLQWQHNKFIPKGMGCWWRVSLLDDELFNNLMQLWLNLNPEQPWHLGSANLQITRILGTPQLTQPWANFCSYGELYEKASDSHRKIDMIFCTPTAFRQGQYDSCLPTRECLFNSLLHRWNKYSQIPLAESLTEYVFPTYVNIHSEIISDKRSKFIGCVGGMGYSILGEASPQIIKDINVLADFALYSGAGRKTPMGMGMIRRLNGA
>NC_019693.1|WP_015151923.1|7500403_7500649_+|hypothetical-protein
MKIQQLIEMLSQFDPDTPVVIQGYEAGYNSISIIEQKSIQMNVNPEHFYGAHGPTDHQPEPVPNVPFVDVIYLGGYNHISR
>NC_019693.1|WP_015151922.1|7498116_7500372_+|type-I-D-CRISPR-associated-helicase-Cas3'
MSNEPLSIQLEPRSIAACTSLPPELAFMGNALQHQVEVYERSRDHDLILALAPTGTGKTKSGLLTLLHQPTKSAVYIAPTNALITQQTEAAKKFVKEAGLDHVVIEASAAKIRQWSNAQVGARSGEKVYNLLRNPATIFPELGPKRPVLLVTNPDIFYYATFFAYNRLDRVNIASGFYTKFSTVIFDEFHLYDAKQLVGLLFYLAHSHIFGFFEQGRRVILLTATPEPACEVVFSNLEAQGVRIARIDGVGTSNLVPSQTAVNLELRSQPTKPEFIAELADEVVRRYQERPDCNGAVILDSLSVVTELYQALKAKGLGDRIGRITGPASATDRKWAMEQSIILATSTVDVGFNFERHPAPTRQNLDWLIFSARDRAAFWQRIGRVGRVLGKTETDIPSEAIGYLPDRAWEQGITNLDCSGGRSALAETLETIQCLDRPFWLAYWRSEAFLEIARPLLEMEEMLENLPQHSLISELFESLRLSLGGKRSWSYYRSRIKDIRAARELAKKPLKLVPGRRHFIQTFLQINCPEDWEDIKFGNADLEDIETIFKTQPEAAQHLKGFAAKWIASYQPIFQFRSGLFESLQIRDPQGLFLDQSAETFLDALHLLRYCNFVSDGEILEIQSPANPPYQVSFRLRYRGKISEFINEEMNKLNAFSGCKIQRGSEDAIAPMPLIESLEKEWFPGVILCPLKNAGPLYRLRQARIESFPITVNCNDGEKTYEFFPGVAGILALATEGVKLRLPDEQDFYCV
>NC_019693.1|WP_015151921.1|7497331_7498120_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1
MSLLTTIENIPANLPLFEQARLVELWCAEPVFFASRELSDAYYTEGVLGNYALAYALGWVRSPYRLSGTATWRPTYLEDLGTLFDCYVLPAWPKQGKVTFRWERFNALSDSYWYAMTNNRVATSREDLPVQREGKKPNSFRPSNFPQSGRLRTIARGNVFQTLVFGDRELPDYIRVGKFMSKVRVEVISKLKQVPLSEGMYQSSAYLNTADLPANLQMLSFDLISIPPAPLVKNLRFQGAAWQFGEIIVPIGIGFCSGGIQS
>NC_019693.1|WP_015151920.1|7496148_7497174_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2
MSIETLNQFLAPTYENFPKGRTIGMVVLRKTQSELILRTEGSGEPMCSEFVQAGFQHKNSIQRLVMTKRKQVAPERRFGREQLRGFELLYPSKNGSVCSLNTNAPCEMCIDCFLYGFAAGGGGAQKSRVWTEDAFSLLPTSETVAERTINAIFETGTMRDENGTASNALNTSEYIKPGVHFLDVVTLKDMTADEMRYVLGNILMTPRYGAVSSRIGRMENQILGIFGGITELPSSLELVQSLYDALIEAKTPLEHPFDTDLLVRMTKDAIASWTNRRGISMQLTEEQLTAVIADVDRHWDGERETFLKRLDRSYETFRKPPAKASSSRKGKKNTEPVTPEG
>NC_019693.1|WP_015151919.1|7493416_7496137_+|hypothetical-protein
MSQRLRLLKGPPTSLEDRYFSDIRPVLYQLHGKHQQYGVRTGTTLAEHLDSACQFILTVSRQAGVRDPIREILLATAAVHDLNKLGDASGRNVKQLARDRAFLEQQLERACVKSLVPSEDSLELARRLIERHSGHGVSDGMSFSPEPDEMEPWVAMLRAADLFDLGIPEQKRIQKLQTELTVAFERTCSLYQVRISKDLGYITALLLNAAEEILVKQGLTPLAIFPDGVLFEGGGWPGGDLIQKIAARWQSKINEVFGKNIEQLVNPTKDGIKISPQAINQDIDEVVAIAFGFLEKKKGGFKASKIEQDIAKWGQKAGSTALAEAEAVGLVPVSNPEEFAIAEGLKAVYLSYRSIQPQPSTQEVWDLIASEVGISPIHRAAIEPFDPQYARPLFAAKVVTKGREGIEAALRDSLQRRKESESGSDGSEDSTVAPEIRTAVEQLLNLPVPSLLSGFDALTDYITTNPKERSSLGYTSANTEKLRSPNMPPGTKVQMFSNRIPGGMSAEPTRYADSIEALAYQLVAVGGQFPAGSKHEPMYLHFLLPPGSSPELRRIWIEFLRDKARTNPEGGPLQIDERKLYRDNELEFKSSKVVGFAFPQRSDFINGNVLIPLLWGDTNVSVALIKSLWLALELSLSLEIGFPFIVSSHLEIEPSAEVYGKVEGIPTSLVPLLGTGQYSREDAAKILGRLRCLGPLVLAVASPKKRDDCLYDLARATSQPFSLYYVLLRWILREKENPNWEKIWNEICEPLNTLLESLMPDDNHILTQYLKQAAQLAVAGKIWGSYQRTASIEPFGNFIAAIRSQKPYMDLDLVFAALVQNYHTRLDRIVGRITGYKVGATKFEQIKEYYQVLRQLYEEVYQGRAERLTADQKTLEAAYFFFLQEERNKAKAESKISEIELTETVE
>NC_019693.1|WP_015151918.1|7492475_7493342_-|WYL-domain-containing-protein
MIRKKETITLSIPPGTKERLEEIAAELKVLWGDRGSISGLLTAIAQGKFQVGQSLTLTSAQVQALQQANRLLIDTGHSPQAQTLTSLLLDRGNLEAPLRLALQQLVNQPSEVWRLRAEEQIQKQQPFRLFYLNAQERELEYTVRCAQVTFREKRFYLEIWCEETEDIPNTDFPELIHNRCLRLDRIQEIQPIAGEWRNGLDFIEVYLHFYEGLVKAYESKDSDISNEVIGEVRQVVRRVSHPFWLIREILPYGKKCLVVAPQAMRDRVKEEIHAIYQRYLEPDTLPPS
>NC_019693.1|WP_015151928.1|7509380_7509923_-|DUF2231-domain-containing-protein
METSERRISPYPNIPPVIETKDAEYLDSGVTSKLSIAGHPIHPVIVTMPIGLLISALISDVVYWGTTDLFWARASFWLIVGGIISGVAAGLTGMFDFVKIKRVRDRSAGWIHMIGNIGVLLLSIINMWTRLGDPAAPILPWGLVLSLIVASLLGVTGWFGGELTFRHKVGIIGAGPENLP
>NC_019693.1|WP_015151929.1|7510091_7511588_-|lignostilbene-alpha,beta-dioxygenase-like-protein
MQLQNRQPQNLSSNKSYTRQDWQKGYESQPREFDYWIEDIEGEIPPELQGTFFKNGPGLLDINGQPIHHPFDGDGMICKIAINQGRAHFSNRFVQTEGYLAEQKAGKILYRGVFGTQKPGGWLANIFNFKTKNIANTNVIYWGNKLLALWEAAQPHRLDPHTLETLGLDTIQGTLNPGDAFAAHPRIDPHSQSDDAAPCLVNFAVKPGLSSTITIYELNPTGEVVRQHSHSIPGFAFLHDMAITPNTCIFFQNPVRLNLLPFLVGWRSPGQCIDFNPHEKTKIILIPRDGKSAVKIIETEPCFVFHHANAWEENGDIFIDSICYDSFPSVDPDGDFREVDFETVPAGQLWRFQVNLETETVQHQVIETRCCEFPSLHPEQVGRPNRYLYIGTAHALEGNAPLQAVLKLDFKTQTQQIWSAAPRGFTGEPVFVPRPGGTREDDGWLLVLMYDAAHHRSDLVILDAEDLTRGPTARLHLKHHVPYGLHGSFTPEWFGPEA
>NC_019693.1|WP_015151930.1|7512052_7513489_-|folate/biopterin-family-MFS-transporter
MLTSPTNGAKIKTLIKEKLLFGNEPTPELVAILLVYFVQGILGLARLAVSFFLKDELGLGPAEVSALMGIAALPWIVKPLFGFMSDGLPIFGYRRRPYLILSGIFGAVAWIGMATVVDTGWKATALMLLSSLSVAVSDVIVDSLVVERARNESLSHAGSLQSLCWGSSALGGLITAYLSGSLLEHFSTQTVFLMTATFPPIVSAVAWLIAEERVGEDTIGLVQVKEQVMQLKRAIAQKAIWLPTAFLFIWQATPSSDSAFFYFTTNELGFHPEFLGKVRLVTSLASLVGIWLFQRFFKTVPFRTIFRWSTLLSAVLGMTTLLLVTHANRAIGIDDHWFSIGDSLILTVMGQIAYMPVLVLAARLCPPGVEATLFALLMSVTNLAGLLSYEEGALLMHLLGVTETNFDQLWLLVVITNLTTLLPLMFIKWLPNGDVGDDQSAFSEENRQYGDMARLSPDHAGAIEPLQPEPVPELEPSA
>NC_019693.1|WP_015151931.1|7513665_7514499_+|DNA/RNA-non-specific-endonuclease
MSNRNSGFRQVFLAAIACGLAIILAGCPWLWGPPTGLDAHLLLGNPSNATWDPGNADNYLMEKPQYVLSYNRSLGTANWASWQLNSSWVGSADRQDDFRPDESLPEGFYQVRATDYRGSGYDRGHLVPSGDRTASVEDNSSTFVMTNIIPQSAANNREVWNELEQYSRKLVEEGKELYIIAGPEGRGRAIANGRVTVPRYTWKIILVLDRPGSALRDITADTRAIAVLMPNTQRVANTAWRDYRVSIDVLEAATGYDFLSNLPAGIQEAIESRVDNL
>NC_019693.1|WP_015151932.1|7514803_7515193_-|Nuclease-A-inhibitor-like-protein
MTQSITEELANLTQDLLWMSEADYPWEVVSYDCSNVTPENLLEQSNLPSDTLIKTVTIERFFAPALREQSWHNEEERATRNRFQQLFNFLNEQLNDLIVYRFGEVEIDVYVLGTVEDKTVGLKTTLVET
>NC_019693.1|WP_015151933.1|7515341_7516952_-|Hsp70-family-protein
MTGYNIGLDFGTTNSIVSYLGPAGELDAFQYGGPDGHKYVPSFIAYDEGFVEIGMAARTTAANHPEVESYGNFKMRLPLADFSEYFAGNRTPSTVTADYLRELLISKENPYSFINQQGTVNALVVSVPEIWQRDIYNRGRESLQTLIKQLGLPLIHLVSEPVAAAAYYAWEIQRRTRQEGMAPFSGNLLVCDMGGGTFDVSLCRIYGDKKVEVLYFDGEGDCGLDSAGVAFDRHCVQLAYTRKHGHPLDETDPEFLRLIREFETVKIGSHGRGTRKLINCLKEPDIYGDRDLYVFAGGYSINFAEVLEAFTPISAGIHRVMNRLQTWLQQQNLEIDRLFLVGGFSQFLLVQRAISEALAINETDPRFDQTFNITNSAYAISYGACLIANQQVEPTEKYVHTLGIVVDTINAQAEREQRFIQIIKGGSGLDELAKPQFADIPPLVTFQNDTPLSLTLWVDPQSKGMRLKESLPDMVKLPSYESHDSWRVGMRVDRSQIAYLVIEDIPGEKRIEYELGNAIAKMFPGFVLIDEREPDN
>NC_019693.1|WP_083896837.1|7517031_7519053_-|hypothetical-protein
MYQIICQRRKSSSPSSNTIVLISMRESAVAQCPVCQGTYIEGEVKNCSTCGWDLTPYPLTLGRIPDSFLRKERAQLSWARNHWRSQSHSKPVDPEPVTQAQMQLSQLKTQLELSNQERDQLQSLFEQTEEAYWQLHSKVETTHQELESAKKERDQAQSQLESTKKASESVKAQLETSQLKLQEFTQECAQYKSQIHEAAKAYWRLQDRLEQEEKERDRIAGELAKAQSDSKLYQARANQIQRQLDEVENTLKQTSQSHSTGEEVVTELQNQLQQAATAYWQLQSQLTDTQSELNHYKNNGGRVSHEERAQLQTQLQSNSTKSSELETKLALIQTELGEERQERRISESRTTWLLEERSQLQTQLEQANAERMVLQTQLSQTQWQLEVANQENSRLLSATYNSQFTRNTALGQNMKNALSVLFVLLSLTPFLLLFHPRVSEPLLKFALRKGYLTTATNKNLSQINLAGAKLDDSNFSGSILNNANLAEISLINANLQETNLNGASLQSANLKYANLTDASLDWANLTNANLQFANLSGANLVRANLSGANLRGANLTNTQIDINTTRIDSEDLLNWKIVNWPRRNRQLAGLNLSGFNLNNASLIDANLQRSNLQQVNFKNADLRGAKLMGADLTGANLSAAKLTNADMTGAKLEGITTDNLTVCPNGRSGPCQF
>NC_019693.1|WP_015151936.1|7521258_7522683_-|serine/threonine-protein-kinase
MPETGSVLQERYQLQEQLNDNPTRETWLAVDLTTEEFVVVKLLVWGGAKAWESLKLFEREAKVLQNLTHPRIPRYRDYFAIDDGTLWSGLVQEYIPGASLQDWLDRGRRFSEEEVEEIATALLNILCYLHELNPPVLHRDIKPSNIILGEDNEIYLVDFGAAQDRNLLTPGRSFTVVGTYGYTPLEQFGGQAVPASDLYAVGATLVHLLTGVPPADLLQKNLQLEFGDRLSPQFSPYLISWLETLTQTQVDNRYPTASEAIAALEGVATLSPDNAPFYQPDITPIQLRTTPQKLEIILPEPGLKVVTWGLNLWQRGLKLIERTVASLRDNLSTSDIIAQVLVYLLIGIGSLSLLSLVLQVATVILPILIPLGMVACLSEYFERTIVCLERDRNTFEIQKKRLGFTYRRQLGVTAHIQTASIFYDNQKFVMGVALTAGPSPGYYQQYAFGNSGRKLTEEECIWLVQEIEDWLDLE
>NC_019693.1|WP_015151937.1|7523502_7526022_+|phosphoenolpyruvate-synthase
MVSTAPEQQSAQGSKETQFVLVFEEVGLADLGLVGGKNSSLGEMIQQLKSKGVNVPTGFATTAYAYRYFIEKAGLEQKLRTLFADLDLNDVNNLRERGKQARAMVMNTPFPKELDDAIAAAYLKLCQGYGANAEFCKRFGPEYQEICEKFSSDLDVAVRSSATAEDLPDASFAGQQETYLNVHGVKGVLESCHKCFASLFTDRAISYRHQYASKRPDFDEFSVALSVGVQKMVRSDLASSGVMFSIDTETGFKNAALVTAAYGLGENVVQGAVNPDEYFVFKPTLKEGKRPILEKRLGSKEIKMVYDVGGSKLTKNVPVSVPERDQYCINDDEILTLAKWACIIEDHYSESRGKYTPMDIEWAKDGITGELFIVQARPETVQSQKAGNVIRNFKLNGTSDIVVRGRAVGEMIGQGKARVILDVHNLDLFQQGEVLVTNKTDPDWEPIMKKASAIVTNQGGRTCHAAIIAREMGIPAIVGCGTATQDIKSGQEVTVSCSEGEEGKVYEGLVPFEILETAIDNLPRTNTKILMNVGNPEEAFGLSSIPCDGVGLARFEFIIANHIKAHPLALIHFDTLEDQAVKKEIGELTKLYSHKPDFFVDKLAHGIGTIAAAFYPNPVVVRMSDFKSNEYANLLGGKQFEPKEENPMIGWRGASRYYDPNYTEAYGLECVALKRVRDDMGLTNVIPMIPFCRTPDEGRKVLETMEKYGLKRGENGLQVYVMCEIPSNVILAEQFAEVFDGFSIGSNDLTQLTLGLDRDSSLVAHIFDERNQAVKDMVTMVIKTAKKTGRKIGICGQAPSDYPEFARFLVELGIDSISLNPDSVMKTLLDIAKLEESMK
>NC_019693.1|WP_156824122.1|7526534_7527281_+|cobalt-precorrin-6A-reductase
MLILGGTGDARELADRMDEMPGVEVMTSLAGRTRHPVVRSPQTRIGGFGGVAGLSQYLREQHIDLLIDATHPFAEQISGNAAEAAAAVGIPRLMLMRPGWERREGDCWIEVESHADAAGVLPTLAQRIFLTIGRQELAAFAHLQDLWFLMRMIDPPSPDAAVPPGRLLLERGPFDLAEERSLLQQYKIGAIVSKNSGGDATYAKIIAARELGIPVVMIQRAPVPEGDRVADVEGALAWLKNRLSPFNN

Crispr_ID: NC_019693_81

• CRISPR_ID: NC_019693_81
• CRISPR_location: 7551216-7551333
• CRISPR_type: Orphan
• Repeat_type: N:A
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_81

Consensus_repeat	Method
TAGGGAAGGGGGCTGGGGGGTTAGGTCTCTTTTC	CRISPRCasFinder

spacers of NC_019693_81

>81.1|7551250|50|NC_019693|CRISPRCasFinder
CAATTTGATTGCCGGAGGGGGCAATAAATCTCTTTCTCCCCCTTCCCTCT

CRISPR arrays and Neighbor proteins around NC_019693_81

CRISPR arrays

The CRISPR arrays of NC_019693_81

>merge|NC_019693|81|7551216-7551333|CRISPRCasFinder
TAGGGAAGGGGGCTGGGGGGTTAGGTCTCTTTTCCAATTTGATTGCCGGAGGGGGCAATAAATCTCTTTCTCCCCCTTCCCTCTTAGGGAAGGGGGCTGGGGGGTTAGGTCTCTTTTC

>NC_019693|81|79|7551216-7551333|CRISPRCasFinder
TAGGGAAGGGGGCTGGGGGGTTAGGTCTCTTTTC	CAATTTGATTGCCGGAGGGGGCAATAAATCTCTTTCTCCCCCTTCCCTCT
TAGGGAAGGGGGCTGGGGGGTTAGGTCTCTTTTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015151957.1|7546955_7547489_-|cytochrome-b6-f-complex-iron-sulfur-subunit	unknown	unknown	gnl|CDD|237392
NC_019693.1|WP_015151969.1|7556047_7557373_-|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223523
NC_019693.1|WP_015151962.1|7549940_7551011_-|CoB--CoM-heterodisulfide-reductase-iron-sulfur-subunit-A-family-protein	unknown	unknown	gnl|CDD|224070
NC_019693.1|WP_015151956.1|7546483_7546921_-|hypothetical-protein	unknown	unknown	gnl|CDD|238431
NC_019693.1|WP_015151966.1|7552609_7553317_-|hypothetical-protein	unknown	unknown	gnl|CDD|224072
NC_019693.1|WP_015151953.1|7544366_7544831_-|rhodanese-like-domain-containing-protein	unknown	unknown	gnl|CDD|238089
NC_019693.1|WP_083896839.1|7560786_7561395_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|273284
NC_019693.1|WP_015151961.1|7549327_7549930_-|hypothetical-protein	unknown	unknown	gnl|CDD|224072
NC_019693.1|WP_015151968.1|7554754_7555837_-|photosystem-II-q(b)-protein	unknown	unknown	gnl|CDD|130221
NC_019693.1|WP_015151960.1|7548461_7549331_-|heterodisulfide-reductase-subunit-B	unknown	unknown	gnl|CDD|224959
NC_019693.1|WP_015151955.1|7545791_7546247_-|DUF2214-family-protein	unknown	unknown	gnl|CDD|378336
NC_019693.1|WP_015151967.1|7553846_7554386_-|rhodanese-like-domain-containing-protein	unknown	unknown	gnl|CDD|238089
NC_019693.1|WP_015151958.1|7547533_7547740_-|DUF2892-domain-containing-protein	unknown	unknown	gnl|CDD|378561
NC_019693.1|WP_015151971.1|7561467_7562070_-|FMN-reductase	unknown	unknown	gnl|CDD|223728
NC_019693.1|WP_015151959.1|7547826_7548363_-|DUF2202-domain-containing-protein	unknown	unknown	gnl|CDD|153107
NC_019693.1|WP_083896838.1|7558487_7559648_+|hypothetical-protein	unknown	unknown	gnl|CDD|366367
NC_019693.1|WP_015151964.1|7551360_7552407_-|heterodisulfide-reductase-subunit-B	unknown	unknown	gnl|CDD|224959
NC_019693.1|WP_015151970.1|7557641_7558337_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293810
NC_019693.1|WP_015147826.1|7559679_7560750_-|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NC_019693.1|WP_015151954.1|7544870_7545695_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293799

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015151957.1|7546955_7547489_-|cytochrome-b6-f-complex-iron-sulfur-subunit	gnl|CDD|237392	PRK13474, PRK13474, cytochrome b6-f complex iron-sulfur subunit; Provisional.	2.47333e-111
NC_019693.1|WP_015151969.1|7556047_7557373_-|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|223523	COG0446, HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only].	1.44308e-38
NC_019693.1|WP_015151962.1|7549940_7551011_-|CoB--CoM-heterodisulfide-reductase-iron-sulfur-subunit-A-family-protein	gnl|CDD|224070	COG1148, HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins [Energy production and conversion].	4.92778e-89
NC_019693.1|WP_015151956.1|7546483_7546921_-|hypothetical-protein	gnl|CDD|238431	cd00851, MTH1175, This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme. This domain is a predicted small-molecule-binding domain (SMBD) with an alpha/beta fold that is present either as a stand-alone domain (e.g. NifX and NifY) or fused to another conserved domain (e.g. NifB) however, its function is still undetermined.The SCOP database suggests that this domain is most similar to structures within the ribonuclease H superfamily. This conserved domain is represented in two of the three major divisions of life (bacteria and archaea).	1.18771e-22
NC_019693.1|WP_015151966.1|7552609_7553317_-|hypothetical-protein	gnl|CDD|224072	COG1150, HdrC, Heterodisulfide reductase, subunit C [Energy production and conversion].	3.5788e-27
NC_019693.1|WP_015151953.1|7544366_7544831_-|rhodanese-like-domain-containing-protein	gnl|CDD|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	8.74841e-29
NC_019693.1|WP_083896839.1|7560786_7561395_+|STAS-domain-containing-protein	gnl|CDD|273284	TIGR00815, Sulfate_transporter, high affinity sulphate transporter 1. The SulP family is a large and ubiquitous family with over 30 sequenced members derived from bacteria, fungi, plants and animals. Many organisms including Bacillus subtilis, Synechocystis sp, Saccharomyces cerevisiae, Arabidopsis thaliana and Caenorhabditis elegans possess multiple SulP family paralogues. Many of these proteins are functionally characterized, and all are sulfate uptake transporters. Some transport their substrate with high affinities, while others transport it with relatively low affinities. Most function by SO42- :H+symport, but SO42- :HCO3- antiport has been reported for the rat protein (spP45380). The bacterial proteins vary in size from 434 residues to 566 residues with one exception, a Mycobacterium tuberculosis protein with 784 residues. The eukaryotic proteins vary in size from 611 residues to 893 residues with one exception, a protein designated "early nodulin 70 protein" from Glycine max which is reported to be of 485 residues. Thus, the eukaryotic proteins are almost without exception larger than the prokaryotic proteins. These proteins exhibit 10-13 putative transmembrane a-helical spanners (TMSs) depending on the protein. The phylogenetic tree for the SulP family reveals five principal branches. Three of these are bacterial specific as follows: one bears a single protein from M. tuberculosis; a second bears two proteins, one from M. tuberculosis, the other from Synechocystis sp, and the third bears all remaining prokaryotic proteins. The remaining two clusters bear only eukaryotic proteins with the animal proteins all localized to one branch and the plant and fungal proteins localized to the other. The generalized transport reactions catalyzed by SulP family proteins are: (1) SO42- (out) + nH+ (out) --> SO42- (in) + nH+ (in). (2) SO42- (out) + nHCO3- (in) SO42- (in) + nHCO3- (out). [Transport and binding proteins, Anions].	4.67489e-39
NC_019693.1|WP_015151961.1|7549327_7549930_-|hypothetical-protein	gnl|CDD|224072	COG1150, HdrC, Heterodisulfide reductase, subunit C [Energy production and conversion].	6.82664e-26
NC_019693.1|WP_015151968.1|7554754_7555837_-|photosystem-II-q(b)-protein	gnl|CDD|130221	TIGR01151, Photosystem_QB_protein, photosystem II, DI subunit (also called Q(B)). This model describes the Photosystem II, DI subunit (also called Q(B)) in bacterial and its equivalents in chloroplast of algae and higher plants. Photosystem II is many ways functionally equivalent to bacterial reaction center. At the core of Photosystem II are several light harvesting cofactors including plastoquinones, pheophytins, phyloquinones etc. These cofactors are intimately associated with the polypeptides, which principally including subunits DI, DII, Cyt.b, Cyt.f and iron-sulphur protein. Together they participate in the electron transfer reactions that lead to the net production of the reducting equivalents in the form of NADPH, which are used for reduction of CO2 to carbohydrates(C6H1206). Phosystem II operates during oxygenic photosynthesis and principal electron donor is H2O. Although no structural data is presently available, a huge body of literature exits that describes function using a variety of biochemical and biophysical techniques. [Energy metabolism, Electron transport, Energy metabolism, Photosynthesis].	0
NC_019693.1|WP_015151960.1|7548461_7549331_-|heterodisulfide-reductase-subunit-B	gnl|CDD|224959	COG2048, HdrB, Heterodisulfide reductase, subunit B [Energy production and conversion].	3.088e-88
NC_019693.1|WP_015151955.1|7545791_7546247_-|DUF2214-family-protein	gnl|CDD|378336	pfam09980, DUF2214, Predicted membrane protein (DUF2214). This domain, found in various hypothetical bacterial proteins, has no known function.	9.16856e-59
NC_019693.1|WP_015151967.1|7553846_7554386_-|rhodanese-like-domain-containing-protein	gnl|CDD|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	3.45463e-31
NC_019693.1|WP_015151958.1|7547533_7547740_-|DUF2892-domain-containing-protein	gnl|CDD|378561	pfam11127, DUF2892, Protein of unknown function (DUF2892). This family is conserved in bacteria. The function is not known.	7.59801e-11
NC_019693.1|WP_015151971.1|7561467_7562070_-|FMN-reductase	gnl|CDD|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	5.456e-25
NC_019693.1|WP_015151959.1|7547826_7548363_-|DUF2202-domain-containing-protein	gnl|CDD|153107	cd01048, Ferritin_like_AB2, Uncharacterized family of ferritin-like proteins found in archaea and bacteria. Ferritin-like domain found in archaea and bacteria, subgroup 2 (Ferritin_like_AB2). This uncharacterized domain is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins whose function is unknown. The conserved residues of a diiron center are present within the putative active site.	2.59339e-46
NC_019693.1|WP_083896838.1|7558487_7559648_+|hypothetical-protein	gnl|CDD|366367	pfam00916, Sulfate_transp, Sulfate permease family. This family of integral membrane proteins are known as the Sulfate Permease (SulP) family. SulP is a large family found in all domains of life. Although sulfate is a commonly transported ion there are many other activities in this family. See the TCDB description for a comprehensive summary.	1.40615e-100
NC_019693.1|WP_015151964.1|7551360_7552407_-|heterodisulfide-reductase-subunit-B	gnl|CDD|224959	COG2048, HdrB, Heterodisulfide reductase, subunit B [Energy production and conversion].	1.26486e-40
NC_019693.1|WP_015151970.1|7557641_7558337_+|MBL-fold-metallo-hydrolase	gnl|CDD|293810	cd07724, POD-like_MBL-fold, ETHE1 (PDO type I), persulfide dioxygenase A (PDOA, PDO type II) and related proteins; MBL-fold metallo-hydrolase domain. Persulfide dioxygenase (PDO, also known as sulfur dioxygenase, SDO, EC 1.13.11.18) is a non-heme iron-dependent oxygenase which catalyzes the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria. Mutations in ethe1 (the human PDO gene) are responsible for a rare autosomal recessive metabolic disorder called ethylmalonic encephalopathy. Arabidopsis thaliana ETHE1 is essential for embryo and endosperm development. Bacterial ETHE1-type PDOs are also called Type 1 PDOs. Type II PDOs (also called PDOAs), are mainly proteobacterial. These enzymes belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.49841e-85
NC_019693.1|WP_015147826.1|7559679_7560750_-|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.69689e-19
NC_019693.1|WP_015151954.1|7544870_7545695_-|MBL-fold-metallo-hydrolase	gnl|CDD|293799	cd07713, DHPS-like_MBL-fold, Methanocaldococcus jannaschii dihydropteroate synthase, Thermoanaerobacter tengcongensis Tflp, and related proteins; MBL-fold metallo hydrolase domain. This subgroup includes Methanocaldococcus jannaschii 7,8-dihydropterin-6-methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate synthase (EC 2.5.1.15), a folate biosynthetic enzyme also known as dihydropteroate synthase and 7,8 dihydropteroate synthase. Thermoanaerobacter tengcongensis Tflp is a ferredoxin-like member. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.44366e-113

Protein sequences

>NC_019693.1|WP_015151962.1|7549940_7551011_-|CoB--CoM-heterodisulfide-reductase-iron-sulfur-subunit-A-family-protein
MNNQVVVIGGGPAGMAAAGKLQDFGFNVVLIEKKPEIGGHLNKWYKVFPDFTDASEITENLKAGLGSTRVLNNATVTEIKGEAPNFQVTISTGEELEAAAILVSTGYKHFDARLKEEYGYGIYDNCITSVELDQMLKAQKVRTRSGKVPKKVAMIHCVGSRDEKVNNNYCSRVCCTNAIKVAIEVKEQNPESEIYCLYMDIRVFGRGYEELYRTSQEEHGVQFLRGRLSEAGEKNDGSLLLRLEDTLTAKPMRLTVDLLVLMVGMEGNPELAEVAGLTLGCDRFYATAHQQYSNNHSTRSGIFLAGAATGPKAIMESITDGRSAAAEIASFLASHPGKSSSNTNGKSVENLTFSVN
>NC_019693.1|WP_015151961.1|7549327_7549930_-|hypothetical-protein
MVTKSTSKRAKKFVFGLKSDRQIDGDKMNSNFIKKVIAEGGDGAAIAACMQCGTCSGGCTNIDLMDMSPRTLILRIQRGEWETVLNSNALWMCSSCYICTSRCPRGVRPSDVIEAVKAIAIRQGIENDSTRFNQIFVDLVQKRGILFEPELMQKYGGLQGLIDQAPLGIKLTLKGKMSPFPDKVKDPKQFNAALEKAKKQ
>NC_019693.1|WP_015151960.1|7548461_7549331_-|heterodisulfide-reductase-subunit-B
MKKYSYYPGCSLHTTAKEFDISTRVVMEELGIELEEIKDWSCCGGSVAAGVSHDMGMAMAARNVALAQKQNLDLLASCSGCYNKSARALKALKQPTEKDRIMAILSEMGVNVADYNIRVRNVVDVLVNDLDIASRVKKPLTGLKVACYYGCLLTRPADITGWDSPMFPTSMDRLSEICGAQVVDFRSKTKCCGGPILVSKQDVAFDLTKKLLDEAKSLGADCIVLACPLCDTNLELRQSDIEKQYNVSYNLPILYITEIIGLALGIKPGKLGINKHIVSPKPVLKKLGL
>NC_019693.1|WP_015151959.1|7547826_7548363_-|DUF2202-domain-containing-protein
MKPDFGKKVNWMPVAMLIGISGILSCTLNPLTARAQTPLDPQTEQAMIDSINDEYRARAFYNAVIEKFGEVRPFSNIVHSEGNHVNLWVNLFERYGVAVPPDEFAGQMSAPDTLQAACAMGVEAEIDNVQMYDRFLEFVTQPDLQAAFRRLRQISEERHLKAFERCQNNAGGRGGRSF
>NC_019693.1|WP_015151958.1|7547533_7547740_-|DUF2892-domain-containing-protein
MFSNVGTLDRIVRLLFAASLLYAGLNLYAGTNLGLGLDIAGALLTFSGLVGFCGLYRFLGISTRKSPN
>NC_019693.1|WP_015151957.1|7546955_7547489_-|cytochrome-b6-f-complex-iron-sulfur-subunit
MDNSLPIESPSMSRRQLLNFLTGSVVAATASAAAYPVAKYFIPPKETTEGGAILAKDILGNPIPASQILAEPPGTRALVAGLAGDPTYLTVQKDGTIDGRGIVDSCTHLGCTFPWNNIDQEFQCPCHGSRYNADGSVLRGPAPLPLKLVQVAVKDNAIWIAPWTAIDPRTGEKPWWV
>NC_019693.1|WP_015151956.1|7546483_7546921_-|hypothetical-protein
MKIAVTSQNKTSITEHAGHCQKFWIYETKDGEIIEKKLVELSADQSFHHCSSNEPHPLDDVQVLISGGMGPGLMRRLERKGIEGVITKETDLDQAVKAYLDGSLVREESECHGGDHGNHKGQNRGQHRGQHRHQHRHHCTSGHQV
>NC_019693.1|WP_015151955.1|7545791_7546247_-|DUF2214-family-protein
MWASSITAYFHYLGFMLAFAALTVEVFNLKKDMTLDEAKRVAFADLVYGIAATAILITGVLRVLYFGKGTDYYLNNPFFYAKMGVFILVSLFSLYPTFTFILWFKDLQNNQPPAVELERVTQLTWLIKAELLGFTILPLLAAVMARMSGWS
>NC_019693.1|WP_015151954.1|7544870_7545695_-|MBL-fold-metallo-hydrolase
MNNFLGITVLVENTAAARGLLGEHGLSYYIETPDSRILFDTGQGLALKHNAQQLGIALPDIDTLVLSHGHYDHAGGLMTVLETSSPRLFLHPSALNPKFSPRGDIGCPIQDPDILAQKSREVIWTETPTEIVPGVYVTGTIPRVHPLEDTGGQFWQDEQQNQVDLMLDDQALFIETIEGVIVVLGCAHAGVINTLNYIATLTGEDKFYGVIGGMHLLNASRDRLQATAETLRKYDLQLIGANHCTGMTAQAFLWQEFALKCRSCSVGTRLFFCR
>NC_019693.1|WP_015151953.1|7544366_7544831_-|rhodanese-like-domain-containing-protein
MRKFVKTLVLILVFCGVMGTVFPAPVQAVSTPYDWVLSETVSQFLDDIPRDYYTIMEIPELKRKSDQENALLIDLRQPNEYAAGHIPQAINIPLRTLPENLDKIPQNRPVILYCTTGYRTGIGVMTLRLLGYTNISAFPPSIQGWKAAGEPLEK
>NC_019693.1|WP_015151964.1|7551360_7552407_-|heterodisulfide-reductase-subunit-B
MKVARENIAWEQHKKQLPTIDDEGGKLWGCFRSCFLQSAAPYTEGIAYKILKNDLGMDLREAPGHTSCGAIGYHGDVTTIEAQMVVAARNFSVAHHELGVDNLFSFCVTSFANYTEMIKLWEEEPELREYTAKTLKETTGREFWIPHVSGGRPSVVHASDVFFANRHKLAAKAKYSLKGIKAVDHIGCHYGKIFPGEAMGGVEFPQTLVGLLEAFGATIVDYPERRHCCGMGFRQCAFPENRDYTASSVYKKMTSLKEAHPDCNLILTNCPGCTVFLDAEQGTIKEVLEEEFNVSVLDYAQLTGLMLGYDPFKDCGLNAKVVEVEPLLDKIGIPYDKSKTAQERRRPF
>NC_019693.1|WP_015151966.1|7552609_7553317_-|hypothetical-protein
MGQLFNELKQDIQYQHGMNACLNCGICTAVCPAAEVYDYSPREVMNICQSEDDQWLIDLLKSDKIWFCGQCYSCKPRCPRGNSTADVILALRRLSIRHGYFAESEKGRQQLFAKRVFGENMLKRGYTLVAENITPEHFPELGENWEYYFEHMAEMRAWWDVPMDLENSAGSHRVIPEKDMEELRAIYKATGAIQLMDAVEKGMEQKLGSKAEVEKFWENWVETADSRTYEMDESQ
>NC_019693.1|WP_015151967.1|7553846_7554386_-|rhodanese-like-domain-containing-protein
MTANQTNQLLDIDALTLKQGLSEQKITLIDVREPGEFAGEHIQGAALLPLSQFDPNSPKLQGDKDIVLYCQSGNRSRQAAQKLLAAGVPEVMQLKGGINGWKQAGYPVEVNKNAPISIFRQVQIVAGTLVFTGTVLGYFVNPGFLFLSGFVGAGLVFAGISNTCAMGMLLAKLPYNQVK
>NC_019693.1|WP_015151968.1|7554754_7555837_-|photosystem-II-q(b)-protein
MTTTVSFPTGNSLWSRFCDWITSTENRLYIGWFGVLMVPTLFTAAIVFVLAFIAAPPVDLDGIREPISGSLLYGNNIVTATIVPTSAAIGLHLYPLWSAASLDEWLYNGGPYQLIVLHFLIGIYAYMGREWELSYRLGMRPWIPVAFSAPVAAATAVLLVYPIGQGSFSDGMMLGISGTFNFMIVFQAEHNILMHPFHQLGVIGVFGGALFAAMHGSLVTSSLVRETSENESTNFGYKFGQEQETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFAALGISTMGFNLNGFNFNQSILDNQGRGINTWADVVNRANLGIEVIHERNAHNFPLDLAAGPVKAIALTAPVIHG
>NC_019693.1|WP_015151969.1|7556047_7557373_-|NAD(P)/FAD-dependent-oxidoreductase
MVNLTQHPSQLQIPQPQTPVRKTIHHQILAIGGGSAGISTSSQLLAKNPALDIAIIEPSDIHYYQPGWTLTGGGVFQIEDTRKPQKDVMPKGVTWIKDKAVKLNPDGNTVITASGLEIEYDCLIVCPGIQIDWHLIKGLKQALGKEGVTSNYSPTYAPYTWETIKNFQGGNALFTFPNTPIKCGGASQKVMYMADDTFRSKWGVRECSNVMFLTADTKMFTVPAYSQILENVVKEREIEVKFQHNLKEIRPETKEAIFDILGESGPVDELSMKYDMIHVAPPQSAPDFIKQSPLAVPNNPYGWVDVDRDTLQHKRYLNVFALGDVSSLPTSKTVAAVRKQAPVLAENLLAFLDSKPLPSRYDGYTCCPLITGYHKTVMAEFDGYNGRLISSFPLNPTKERWIMWLMKKHLMPWIYWNRMLKGSRFEGDYIKFMQWQAGAED
>NC_019693.1|WP_015151970.1|7557641_7558337_+|MBL-fold-metallo-hydrolase
MLFRQLYDNETSTYTYLIADETTKEAVLVDPVIEQVDRDLQLLEELGLTLRYCLETHIHADHITGTGELRSRTNCQGVVPENASAACADRFIKDGETLQVGDIEIKAIATWGHTDSHNAYLINGDRILTGDSLLIRGCGRTDFQSGNPGLLYDCITQKIFTLSGETLVYPGHDYKGRTVSTIGEEKNHNPRFVGKDRDSFIEQMNNLNLPNPKKIAEAVPANQGCGKPAII
>NC_019693.1|WP_083896838.1|7558487_7559648_+|hypothetical-protein
MNGIKQYLPILNWGLHYRREYLIGDITAGIIVASLLIPQGMAYAMLAGLPPEVGLYASILPLIVYACLGTSSNLSVAPVAVDSLMVAAAVSAFAGENTAEYLGLALTLAFLVGIIEIFMGVFRLGFLVNFLSQSVISGFISAAAILIGVSQVKHLLGVKIPQTESFVQLVSYLGAEVANTNGVTLMLGLMALVILIFFNKKVKDYLKQWRVSEAAIVPITKSAPLLLVIFSSLLVWGLRLDEIAGVKVVGTIPQGLPPISLPLFDGTTLQQLFPAALAISFVGFMEAFAVGSFLGSKKRQKLDANQELIALGAANASAAFTGGYPVTGGLSRSVVNFAAGANTGLASMITALVIAITVMFLTPLFYFLPQTILAAIILVAVANLSR
>NC_019693.1|WP_015147826.1|7559679_7560750_-|IS630-family-transposase
MGARLRVFLTPEEDRTLFELRMATTLPQRVKDRASIVRLNAHGWYVEKIASHFNWSVSRVRDTLHRWEKKGLGGLWDKAGRGSKAKWQDADIAYVEECLRQEPRTYNSKQLAKKLAAERQVYLSPDRLRRVLKKKGIIWKRTRISHKNKQDPEERSIKQADLDMLEFAAAAREIDLKYLDESGFCLWSSVGYTYFPKKEQKCQEQTRIRGRRLSILGIMQPKIGFTYGLAIGSFTSKSYIKMMEIEAEEASKELALTGRIRVIVQDNGPIHKSLEVQNKWPSWEEKGLYIFLLPKYCSEMNEIELEWQHLKRDELAGRMFEDELDLAYAVMAGVEARSVEGNYTAKRVKFKSGPSP
>NC_019693.1|WP_083896839.1|7560786_7561395_+|STAS-domain-containing-protein
MFTYFGFFVPTYLLDFGTLKRLWGYDKGDAIAWGAAFIAVLATSVETGILIGAAISLALHLWRTSKPHIAIVGRIENTEHFRNIERYRVKTYPHILAIRIDESLYFANAKYLQTYVQNTISTYPEVKHLVLVCSAVNVIDGSGLEILKSLIEDLKSVGIDFYLAEVKGPVLDKLKTIGFTEFIGGDRIFLTTDIAMKTLECQ
>NC_019693.1|WP_015151971.1|7561467_7562070_-|FMN-reductase
MNSGKKVIGIVGSYRKGGTIDTVVSEVLAEAETQGAEISKIYLQDRQIEFCTNCRVCLQEPGPERGDCVLKDEMDGILQEIEAADSLVIGAPVNFGNINALTQRFLERCVCYGYWPWNTPSPQMRKSEASKKAVLISATAMPGFIARWVSGAIKSLKSLAKMLGAKPIGVIFVGQVTSKKWQLSDKIKRQARDLGQKLVV

Crispr_ID: NC_019693_82

• CRISPR_ID: NC_019693_82
• CRISPR_location: 7581814-7581911
• CRISPR_type: Orphan
• Repeat_type: N:A
• Spacer_info: 1 spacers

Consensus repeat of NC_019693_82

Consensus_repeat	Method
CAAGGGGAGGGTTAGGGTGGGGTTCTTCCCAAGA	CRISPRCasFinder

spacers of NC_019693_82

>82.1|7581848|30|NC_019693|CRISPRCasFinder
TATCGGGCTACTCCGGTCCCCTCCCCTTAG

CRISPR arrays and Neighbor proteins around NC_019693_82

CRISPR arrays

The CRISPR arrays of NC_019693_82

>merge|NC_019693|82|7581814-7581911|CRISPRCasFinder
CAAGGGGAGGGTTAGGGTGGGGTTCTTCCCAAGATATCGGGCTACTCCGGTCCCCTCCCCTTAGCAAGGGGAGGGTTAGGGTGGGGTTCTTCCCAAGA

>NC_019693|82|80|7581814-7581911|CRISPRCasFinder
CAAGGGGAGGGTTAGGGTGGGGTTCTTCCCAAGA	TATCGGGCTACTCCGGTCCCCTCCCCTTAG
CAAGGGGAGGGTTAGGGTGGGGTTCTTCCCAAGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_019693.1|WP_015151994.1|7593498_7594287_-|TatD-family-hydrolase	unknown	unknown	gnl|CDD|223162
NC_019693.1|WP_015151983.1|7573205_7573760_+|hydrogenase-maturation-protease	unknown	unknown	gnl|CDD|99876
NC_019693.1|WP_015151989.1|7578156_7581750_+|pyruvate:ferredoxin-(flavodoxin)-oxidoreductase	unknown	unknown	gnl|CDD|131231
NC_019693.1|WP_015151993.1|7589784_7593090_-|DNA-directed-RNA-polymerase-subunit-beta	unknown	unknown	gnl|CDD|234749
NC_019693.1|WP_015151982.1|7572027_7573188_+|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NC_019693.1|WP_015151984.1|7573771_7574113_+|hydrogenase-maturation-nickel-metallochaperone-HypA	unknown	unknown	gnl|CDD|376468
NC_019693.1|WP_015151991.1|7583458_7587535_-|DNA-directed-RNA-polymerase-subunit-beta'	unknown	unknown	gnl|CDD|235052
NC_019693.1|WP_156824002.1|7589620_7589734_+|BcpO-related-WXXGXW-repeat-protein	unknown	unknown	unknown
NC_019693.1|WP_015151992.1|7587742_7589617_-|DNA-directed-RNA-polymerase-subunit-gamma	unknown	unknown	gnl|CDD|235055
NC_019693.1|WP_015151995.1|7594491_7594797_-|30S-ribosomal-protein-S20	unknown	unknown	gnl|CDD|214366
NC_019693.1|WP_015151981.1|7571519_7572026_+|PAS-domain-containing-protein	unknown	unknown	gnl|CDD|379177
NC_019693.1|WP_044198221.1|7575022_7577335_+|carbamoyltransferase-HypF	unknown	unknown	gnl|CDD|223146
NC_019693.1|WP_015151998.1|7597566_7597962_-|hypothetical-protein	unknown	unknown	unknown
NC_019693.1|WP_015151990.1|7582010_7583036_+|dihydroorotate-dehydrogenase-like-protein	unknown	unknown	gnl|CDD|236051
NC_019693.1|WP_015151985.1|7574116_7574935_+|hydrogenase-nickel-incorporation-protein-HypB	unknown	unknown	gnl|CDD|349775
NC_019693.1|WP_015151980.1|7571250_7571517_+|(2Fe-2S)-ferredoxin-domain-containing-protein	unknown	unknown	gnl|CDD|239278
NC_019693.1|WP_015151997.1|7597068_7597512_+|universal-stress-protein	unknown	unknown	gnl|CDD|366180
NC_019693.1|WP_015151987.1|7577343_7577577_+|HypC/HybG/HupF-family-hydrogenase-formation-chaperone	unknown	unknown	gnl|CDD|376549
NC_019693.1|WP_015151979.1|7569688_7571113_+|Ni/Fe-hydrogenase-subunit-alpha	unknown	unknown	gnl|CDD|225798
NC_019693.1|WP_015151996.1|7595408_7596710_+|histidinol-dehydrogenase	unknown	unknown	gnl|CDD|376389

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_019693.1|WP_015151994.1|7593498_7594287_-|TatD-family-hydrolase	gnl|CDD|223162	COG0084, TatD, Mg-dependent DNase [DNA replication, recombination, and repair].	4.58396e-120
NC_019693.1|WP_015151983.1|7573205_7573760_+|hydrogenase-maturation-protease	gnl|CDD|99876	cd06066, H2MP_NAD-link-bidir, Endopeptidases that belong to the bidirectional NAD-linked hydrogenase group. This group of endopeptidases are highly specific carboxyl-terminal protease (HoxW protease) which releases a 24-amino-acid peptide from HoxH prior to progression of subunit assembly. These bidirectional hydrogenases are heteropentamers encoded by the hox (hydrogen oxidation) genes, in which complex HoxEFU shows the diaphorase activity, and HoxYH constitutes the NiFe-hydrogenase.	1.07203e-52
NC_019693.1|WP_015151989.1|7578156_7581750_+|pyruvate:ferredoxin-(flavodoxin)-oxidoreductase	gnl|CDD|131231	TIGR02176, pyruvate_flavodoxin/ferrodoxin_oxidoreductase, pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric. This model represents a single chain form of pyruvate:ferredoxin (or flavodoxin) oxidoreductase. This enzyme may transfer electrons to nitrogenase in nitrogen-fixing species. Portions of this protein are homologous to gamma subunit of the four subunit pyruvate:ferredoxin (flavodoxin) oxidoreductase.	0
NC_019693.1|WP_015151993.1|7589784_7593090_-|DNA-directed-RNA-polymerase-subunit-beta	gnl|CDD|234749	PRK00405, rpoB, DNA-directed RNA polymerase subunit beta; Reviewed.	0
NC_019693.1|WP_015151982.1|7572027_7573188_+|SpoIIE-family-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	1.46548e-12
NC_019693.1|WP_015151984.1|7573771_7574113_+|hydrogenase-maturation-nickel-metallochaperone-HypA	gnl|CDD|376468	pfam01155, HypA, Hydrogenase/urease nickel incorporation, metallochaperone, hypA. HypA is a metallochaperone that binds nickel to bring it safely to its target. The targets for Hypa are the nickel-containing enzymes [Ni,Fe]-hydrogenase and urease. The nickel coordinates with four nitrogens within the protein. The four conserved cysteines towards the C-terminus bind one zinc moiety probably to stabilize the protein fold.	1.38208e-44
NC_019693.1|WP_015151991.1|7583458_7587535_-|DNA-directed-RNA-polymerase-subunit-beta'	gnl|CDD|235052	PRK02597, rpoC2, DNA-directed RNA polymerase subunit beta'; Provisional.	0
NC_019693.1|WP_015151992.1|7587742_7589617_-|DNA-directed-RNA-polymerase-subunit-gamma	gnl|CDD|235055	PRK02625, rpoC1, DNA-directed RNA polymerase subunit gamma; Provisional.	0
NC_019693.1|WP_015151995.1|7594491_7594797_-|30S-ribosomal-protein-S20	gnl|CDD|214366	CHL00102, rps20, ribosomal protein S20.	4.43381e-31
NC_019693.1|WP_015151981.1|7571519_7572026_+|PAS-domain-containing-protein	gnl|CDD|379177	pfam13426, PAS_9, PAS domain.	1.25786e-08
NC_019693.1|WP_044198221.1|7575022_7577335_+|carbamoyltransferase-HypF	gnl|CDD|223146	COG0068, HypF, Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones].	0
NC_019693.1|WP_015151990.1|7582010_7583036_+|dihydroorotate-dehydrogenase-like-protein	gnl|CDD|236051	PRK07565, PRK07565, dihydroorotate dehydrogenase-like protein.	0
NC_019693.1|WP_015151985.1|7574116_7574935_+|hydrogenase-nickel-incorporation-protein-HypB	gnl|CDD|349775	cd05390, HypB, nickel incorporation protein HypB. HypB is one of numerous accessory proteins required for the maturation of nickel-dependent hydrogenases, like carbon monoxide dehydrogenase or urease. HypB is a GTP-binding protein and has GTP hyrolase activity. It forms homodimer and is capable of binding two nickel ions and two zinc ions. The active site is located on the dimer interface. Energy from hydrolysis of GTP is used to insert nickels into hydrogenases.	1.91453e-105
NC_019693.1|WP_015151980.1|7571250_7571517_+|(2Fe-2S)-ferredoxin-domain-containing-protein	gnl|CDD|239278	cd02980, TRX_Fd_family, Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:ubiquinone oxidoreductase (NuoE). TRX-like Fds are soluble low-potential electron carriers containing a single [2Fe-2S] cluster. The exact role of TRX-like Fd is still unclear. It has been suggested that it may be involved in nitrogen fixation. Its homologous domains in large redox enzymes (such as Nuo and hydrogenases) function as electron carriers.	1.23319e-06
NC_019693.1|WP_015151997.1|7597068_7597512_+|universal-stress-protein	gnl|CDD|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	1.70073e-24
NC_019693.1|WP_015151987.1|7577343_7577577_+|HypC/HybG/HupF-family-hydrogenase-formation-chaperone	gnl|CDD|376549	pfam01455, HupF_HypC, HupF/HypC family.	1.54609e-31
NC_019693.1|WP_015151979.1|7569688_7571113_+|Ni/Fe-hydrogenase-subunit-alpha	gnl|CDD|225798	COG3259, FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion].	0
NC_019693.1|WP_015151996.1|7595408_7596710_+|histidinol-dehydrogenase	gnl|CDD|376389	pfam00815, Histidinol_dh, Histidinol dehydrogenase.	0

Protein sequences

>NC_019693.1|WP_015151989.1|7578156_7581750_+|pyruvate:ferredoxin-(flavodoxin)-oxidoreductase
MSTRTFATLDANEAVARVAYKLNEVIAIYPITPASPMGEWADAWMSEGRPNLWGTIPSVVEMQSEAGAAGTVHGALQTGSLTTTFTASQGLLLMIPNLYKIAGELTCAVIHVAARSLAAQALSIFGDHSDVMAVRSTGFALLCSASVQEAHDFALIAQSATLKSRVPFIHFFDGFRTSHEIQKVELLEDEDLRSLIDDAGVFAHRDRALTPDRPVLRGTAQNPDVYFQARETVNPFYTDCSDIVQQAMDEFGELTGRKYQLFEYHGAPDPSCLVILMGSGCETVHETVDYLNAQGEKVGVLKVRLYRPLDMKRLVAAIPETVKAIAVLDRTKEPGAGGDPLYLDVVTAMHEEWTGDRLPKLVGGRYGLSSKEFTPAMVKAIFDNLSQAKPKNHFTIGINDDVTHTSLDYDPNFSTEPDSVVRAMFYGLGADGTVGANKNSIKIIGEETDNYAQGYFVYDSKKSGAITISHLRFGPQPIRSTYLIEQANFVGCHQWIFLEKLDVLSAAAPGAIFLLNSPYAHEEVWNQLPIETQEKIVRKGLKVYTIDANKVARESGMSGRINTVMQVCFFALAGVLPRDEAIAQIKKAIEKTYGKKGKEIVRMNLQAVDNTLANLFEVTLGQANSSLHKQPAVPDLAPAFVRDVEGKMLVKEGEVLPVSALPCDGTYPTATSKWEKRNIATEIPVWDPDVCVQCGKCIMVCPHAVIRGKVYEPAELANAPATFKATDTKDKDFAGTQFTIQVSPEDCTGCGICVEVCPAKNKSMPSLKAINMEPQIPLREPERENWEFFMNLPNPDRRTLHLDRIRQQQLQEPLFEFSGACAGCGETPYLKLVSQLFGDRSVIANATGCSSIYGGNLPTTPWAQNAEGRGPAWSNSLFEDNAEFGLGFRVSIDKQAQFAGELVQKLSSEIGDNLVTGILNATQKNEADIWEQRDRVAALKEKLQGMNSPDAKQLASLADYLVKKDVWIIGGDGWAYDIGYGGLDHVIASGRNVNILVLDTEVYSNTGGQASKATPRGAVAKFAAGGKPAAKKDLGLIAMTYGNVYVASVAMGARDEHTLKVFLEAEAYDGPSLIIAYSHCIAHGINMTTAMNHQKEMVEAGRWLLYRYNPDLVEQGKNPLQLDMRSPKKGVEYSMYNENRFKMLTKTKPADAKRLLAEAQNDINTRWQMYEYLASRHLETHNGEAAVAPAAPAAPAG
>NC_019693.1|WP_015151987.1|7577343_7577577_+|HypC/HybG/HupF-family-hydrogenase-formation-chaperone
MCLAIPGQIISISDDAEPLMRSGRVSFGGVVKTVNLAYVPEAQVGDYAIIHVGFALSIIDEDEAQETLDYFKQIQEV
>NC_019693.1|WP_044198221.1|7575022_7577335_+|carbamoyltransferase-HypF
MHNLTRLSITVRGAVQGVGFRPFIYRLATELQLNGWVNNSAEGVFIEVEGSREQLETFLLRLEREKPAISFIQSLESTWLEPVGFTEFEIRPSVAGKKTAVVLPDIATCPDCLQEIFDFQNRRYGYPFTNCTNCGPRYTIIRGLPYDRANTSMQGFQMCPDCQAEYDNPLNRRFHAQPNACPNCGPQVEFWTGLDTVLARGDRALETAISLINLGQILAVKGLGGFHLIVDAGNSAAVRHLRHCKRREEKPFAVMYPSLEQVRQDCQVTAIEERLLRSPECPIVLLRRLSDSDTNIAPEVAPDNPYLGVMLPYTPLHHLLLAGLGKPVVATSGNLSDEPICIDEQEAGDCLKDIADGFLVHNRPIVRAVDDSVVRVVAGREMVMRRARGYAPLPISLKVTADSPPSPPPILAVGAHLKSAVAIGVFPQIFVSQHLGDLETPQAFQAFQEATASLQQLYEATPQVVARDAHPNYRSTRFAEGLELPQMEVQHHYAHVLSCMAENQLLEETVLGVAWDGTGYGLDGTIWGGEFLRVSPTSWDRVAHFRTFPLLGGDKAVKEPRRVALGLLYEVLGSRLFTPQMSQQCQHILQAFTPLELTLLRSMLEKQINTPITSSVGRLFDGVAAIAGLKSQISFEGQAATALEFALEGWTTQESYPLPIQTGDGVAIADWEPTILAILRDVGSRVPIGIISAKFHNTLVESILTVAQWIGEERIVITGGCFQNAYLTERVIRQLKLKGFRPYWHQRIPPNDGGIALGQVVAAYRNLNQE
>NC_019693.1|WP_015151985.1|7574116_7574935_+|hydrogenase-nickel-incorporation-protein-HypB
MCTNCGCSVVGEVGIHTHSHENGHSHSHENGHTHSHENGHHHHHHHDEPHQTIAVGQAVLAKNDRLAERNRGYFMAKNLLVLNVLSSPGSGKTAFLERMVQDIGSRIPTGIIVGDLETDNDAIRLSNSGAAAVQITTGTVCHLESDMVLKAAQQLNLDALDVLVIENVGNLVCPAAYDLGEDLRLVLLSVTEGEDKPLKYPTMFKSAQVVIISKVDIAEAVEFDREKALENIRKIAPQAAIFEVSARKGQGMAEWYGYLEQHLKKSPVSAVS
>NC_019693.1|WP_015151984.1|7573771_7574113_+|hydrogenase-maturation-nickel-metallochaperone-HypA
MHEVSLMENTLNIALDCASAQNASKIHRLKMRVGDLSGVVPDALEFAFDVVTRGTIAEGAKFEIERVPVVCHCSTCDRNFEPIDLFYECPHCHQLTYQIQSGQEIELTSLEVS
>NC_019693.1|WP_015151983.1|7573205_7573760_+|hydrogenase-maturation-protease
MLSIQQESPAILAIGYGNDLRRDDGVGQRVAEEVASWGLPKVRSLSQHQLTPELAEPLSEVDLAIFIDAYPATEEQGLQVVKLDGDDSMSPQSLGHSSDPSSLLILAKTLYGKSPQGWLVAIPGMDFEFGETFSAMTEQGMAEALVAIAELIETGVKDGGELGDGGELGDGGELGNGGDGEEYR
>NC_019693.1|WP_015151982.1|7572027_7573188_+|SpoIIE-family-protein-phosphatase
MDSFLDIFDLSLNKKGEELCGDRVRFRKTPDKTTIVLSDGLGSGVKANILATLTTEILISMLNEDVPLEEVIKTVIGTLPICQVRKIAYATFTILQIDNHTDLFKVINFDNPPPLYFDQGKLVKLEGKTEKILEKKITVYEGRLKEGDFLGCMSDGVLYAGLGVALNFGWGWDNVAQYIEGLFLTQTRNARRIVQKTIAETHSLYGGKIGDDATFVGVYVRQRNPLMIFTGPPLDNSHDQQYVERLLTFEGRKVVCGGTTGNIVAKYLGETIEMDISTMRRDLPPIGKLSAIDLVTEGILTLSKCLEVLKNCNCDITRLPSDQNGSVLLAKEILQADSILFMVGQKINEFYQNPLLPKNISIRRSLVEEVVKFLRDKQKEVTLEYC
>NC_019693.1|WP_015151981.1|7571519_7572026_+|PAS-domain-containing-protein
MVTNEKTLWELLWEYDPNGLIVVNEDMTIAVVNPAFCKMFKITADEMVGKPAVALLGTVDEFQRVWEKNEVIRGKEKEYPKYDLYVRQVMFSIRDQNAIACIMVDITDEWQRKKELLELKRETVAKVNEVVDNQMKVAQEIAGLLGETTAETKVSLLKILKLVEGETL
>NC_019693.1|WP_015151980.1|7571250_7571517_+|(2Fe-2S)-ferredoxin-domain-containing-protein
MTKENLYLCMGSACHQLGVYEVLPQLQELITRYDLEDKIELKGSFCLETCSVGIVMKFKEKVFTKINPENIETKFQEEILPSILAVVQ
>NC_019693.1|WP_015151979.1|7569688_7571113_+|Ni/Fe-hydrogenase-subunit-alpha
MPKTIVIDPVTRIEGHAKISVYLDDAGEVEDARFHVVEFRGFEKFCEGRPMWEMAGITARICGICPVSHLLASAKTGDKIQAVKIPPAGEKLRRMMNLAQITQSHALSFFHLSSPDFLLGWDSDPAKRNVFGLIAADPDLARSGIRLRQFGQKIIELLGAKKIHPSWAVPGGVRSPLSEESCTWIRDRLPESRQTIEMALGLFKTLLDRFSTEVETFGKFPSLFMGLVGKDGLWEHYDGHIRFTDSDGNIVADNLSEDDYESYLGEAVESWSYLKFPYYKPLGYPNGIYRVGPLARVNICSRMGTEAADRELLEFRDRAGGVATSSFYYHYARLIEILCAIEHIEQLVNDPDVVSPRTRATAGINNLEGVGVSEAPRGTLFHHYKVDENGLIKKVNLIIATGQNNLAMNKTVTQIAQHFIHGNEIQEGMLNRVEAGIRAFDPCLSCSTHAAGQMPLHIELIDAKGTVVNEVYRH
>NC_019693.1|WP_015151990.1|7582010_7583036_+|dihydroorotate-dehydrogenase-like-protein
MDLTTEYLGLQLKSPLMPSAAAPLTEDLDNIKRLEDAGAGAIALHSIFAEQLKIEQHELHHHTISHTESFAEALTYFPDPDTYHVGPETYLEHIRQAKESVEIPIIASLNGYTLGDWVDYSKQIQEAGADALELNIYSIPTDPHLTGAQIEEDYLSIVEAVRADVTIPLAVKLSPYFTNLANMAMRLDKAGANGLILFNRFMQADISPEELEVWPHLVLSHHQESLLPMRWLGLLYGRINADLAATTGIQKGRDAVKMLMVGAKVTQVCSPLLRHGIGHLREIERELVEWLEEHEYHSVKQAIGTMSQMNVADRSAYERAQYMKVIQSFDYDQAIVTASTV
>NC_019693.1|WP_015151991.1|7583458_7587535_-|DNA-directed-RNA-polymerase-subunit-beta'
MTKKNFTFYNRVINKGQIKSLISRTFVQHGTARSAQIADRLKDLGFRYATKAGVSISVDDLMIPPSKRDLLMGAEREITLTESRYARGEITEVERFQKVIDTWNSTSESLKDEVVRHFKETDPLNSVYMMAFSGARGNVSQVRQLVGMRGLMANPQGEIIDLPIKTNFREGLTVTEYIISSYGARKGLVDTALRTADSGYLTRRLVDVSQDVIVREVDCGTTRGIPMESMKDEDRILIPLSDRLFGRVAAEDVISPKTGEVIAARNQPMDDDISENIMKHGVERVMVRSPLTCEASRSVCQLCYGWSLAHGKLVDMGEAVGIIAAQSIGEPGTQLTMRTFHTGGVFTAEVARTVTAAFSGTVHYSPTMRARAFRTRHGEDAFVVENAKSEITLQSEGRKEVFDVFQGTVLLVPDGAAVERLTLLAEVPLPGRTRRTTEKATKDVATDLAGEVVFADLMPEEKKDRQGNATRTATRGGLVWILSGEVYNLPPGAEPVVKNGDRIQPGGVLAETKLITDNGGIVRLPEEMENRPSSMPREVEIITASVTLDRATVYATSTGGRDHYTIETIGKQLFSLKATPGTKVLNHQVVAELIDETYRTHSGGIIKYAGVEVLKRGKAKQGYEVVKGGTLLWIPEECHEINKDISLLLVEDGQFVEAATEIVKDIKCASSGVVEVTQKNDILREVTIKPGELIMIEDPEEVAIANGSLVNPGQEIIPGLVAQELRYVEILETPEGPALLLRPAVEYPVLDEPAIPSQESLNNGEEAMIQLRAVQRLPYKDGERVKSVEGLELLRTQLVLEIDKDAPGLAADIELVPVEEEELLSSEELDPSKGAPMRLQLVILESLVIRRDVVADTTQGSTQTRLLVKDGDRIPPGAVVARTEILGKEAGEIRGIREGAEAIRRVLVVRDEDVITVETAIEPTVKVWDFLVENTEVTPGVRIPESGQVVEMTALEPQEDTALSQGNYRMKLRLARPYRVSPGAVLHVDDGSLVQRGDNLVLLVFERAKTGDIIQGLPRIEELLEARKPKEGCVLAALPGVAQVVYGDDDTVILKVVEEDGAVTDYELGPGQPLLVSDGQRVKAGEPLTDGPSNPHEILEIFFNLPGERNYEHTLFSFQQVQTFLVSEVQSVYLSQGIDISDKHIEVIVRQMTNKVRIDDGGDTTMLPGELIELQQVERVNEAMSITGGAPAKYTPLLLGITKASLNTDSFISAASFQETTRVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGFNAYEDMMLLPDDAAYDGVLDEEEEEFPDVVLDDHTARAYRNTGLEMDEEIIAEEEEESDSDEFALPDLGVKVGKEVRSISMLEEDFEEDDDFDDDDDIDDDFE
>NC_019693.1|WP_015151992.1|7587742_7589617_-|DNA-directed-RNA-polymerase-subunit-gamma
MPKIEQRFDYVKIAIASPDRIRQWGERTLPNGQVVGEVTKPETINYRTLKPEMDGLFCERIFGPAKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVAHVWYLKGIPSYIAILLDMPLRDVEQIVYFNAYCVLSPGNADNLQYKQLLSEDAWMEIEDQLYSEDTELIGIEVGIGAEALQRLLQDLELETEAEKLREEIANSKGQKRAKLIKRLRVIDNFIATGSQPDWMVLEYIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIIRNEKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKIHQCGLPREMAIELFQPFVIHRLIRQGLVNNIKAAKKLIQRADPSVWDVLEEVIESHPVLLNRAPTLHRLGIQAFEPILVEGRAIQLHPLVCPAFNADFDGDQMAVHVPLGLEAQAEARLLMLASNNIMSPATGRPIVTPSQDMVLGCYYLTAHNPNAHKGAGGYFSSLQDAIIAYEQGLIELHALIWVRLDVNWEVDSDEKETEPKITQHSDGSVTKLYADRRIREDAQGNILSQYIQTTAGRIIFNKTIADVLI
>NC_019693.1|WP_156824002.1|7589620_7589734_+|BcpO-related-WXXGXW-repeat-protein
MISPCKLCPWSLVLGHWSLVHGRWSFVIGHWSLVLGR
>NC_019693.1|WP_015151993.1|7589784_7593090_-|DNA-directed-RNA-polymerase-subunit-beta
MNNPTYPAATAFTLPDLVEIQRASFRWFLELGLIEELDSFSPITDYTGKLELHFIGKDYKLKRPKYDVDDAKRRDSTYAVQMYVPTRLINKETGEIKEQEVFIGDLPLMTERGTFIINGAERVIVNQIVRSPGVYYKSETDKNGRRTYNASLIPNRGAWLKFETDKNDLVWVRIDKTRKLSAQVLLKALGLTNNEIFDALRHPEYFQKTIEKEGEFTEEEALMELYKKLRPGEPPTVSGGSQLLESRFFDPKRYDLGRVGRYKLNKKLRLSVPDNVRVLTPQDILTAIDYLINLEFDVGQSDDIDHLGNRRVRSVGELLQNQVRVGLNRLERIIRERMTVSDADSLTPASLVNPKPLVAAIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLTRERAGFAVRDIHPSHYGRICPIETPEGPNAGLIGSLATHARVNPYGFIETPFYPVENGRVLRERGALFMTADEEDDLRVAPGDITVDEGGYIQGETVPVRYRQDFTTTTPDQVDYVAVSPVQIISVATSLIPFLEHDDANRALMGSNMQRQAVPLLLPERPLVGTGLEAQAARDSGMVVVSRTDGMVTFVDATKIRVQDPQGREMEYQLQKYQRSNQDTCLNQRPLVFEGDDVVAGQVLADGSSTEGGELALGQNIIVAYMPWEGYNYEDAILISERLVYDDLYTSIHIEKYEIEARQTKLGPEEITREIPNVGEDSLRQLDEGGIIRIGAWVESGDILVGKVTPKGESDQPPEEKLLRAIFGEKARDVRDNSLRVPNGEKGRVVDVRVFTREQGDELPPGANMVVRVYVAQKRKIQVGDKMAGRHGNKGIISRILPIEDMPYLPDGTPLDIVLNPLGVPSRMNVGQVFECLLGWAGQNLGSRFKVVPFDEMHGPEKSRESVHGKLQEARQKTGKDWIFNEDHPGKTLVYDGRTGEAFDRPITVGKAYMLKLVHLVDDKIHARSTGPYSLVTQQPLGGKAQQGGQRFGEMEVWALEAFGAAYTLQELLTVKSDDMQGRNEALNAIVKGKAIPRPGTPESFKVLMRELQSLCLDIAVHKVQTQDDGTSRDVEVDLMADVANRRTPSRPTYESVSREALEEEEEE
>NC_019693.1|WP_015151994.1|7593498_7594287_-|TatD-family-hydrolase
MQLIDTHVHINFERFDRDLEAVRERWHEAGVVHLVHSCVTPEEFGTIQGLANRFGEISFAVGLHPLEAHQWSSQLGDRIEELAASEARVVAIGETGLDFYKAENKQQQQEAFIAQLEIAQGLNKAVIIHCRDASEEMAELLQSFWRDRGPVPGVMHCWGGTPEETQWFLDLGFYISFSGIVTFKNAHSIQESARLVPSDRLLVETDCPFLAPVPKRGKRNEPAYVRYVAEQVATLRGVSLETLAAETTENACRLFQLTLKMS
>NC_019693.1|WP_015151995.1|7594491_7594797_-|30S-ribosomal-protein-S20
MANIKSAIKRVQITERNRLRNKSYKSAVRTLIKKCVTSAEQYGSNPTPELKEEIHNRLNAAYSKIDKAVKRGVLHPNNGARKKSNLARVVKQQVLAQSSAS
>NC_019693.1|WP_015151996.1|7595408_7596710_+|histidinol-dehydrogenase
MLRIITQRAEAQAELRRICDRTHDDQVVHKEATVREVLQAVKRQGDRSLLHYTAEFDGQSLKPEDLRVSGSELDAAYQQVSKELLDAIGLAKQNIEAFHRQRVPKSWVQFGEDEVVLGKRYTPVDRAGLYVPGGRAAYPSTVLMNAIPARVAGVPRIVICTPPGPEKTVNPAVLVAAQEAGIQEIYRVGGAQAIAALAYGTETIPKVDVITGPGNIYVTLAKKQVFGTVGIDSLAGPSEVLIIADSQGNPAHIATDLLAQAEHDPLAAAILITTDAQIARKVVAQVEDQLIDHPRRTLTEKAIAHYGVVIVVDSLQIAAELSNEFAPEHLELEVSDPWDLLEYIRHAGAIFLGNSTPEAVGDYLAGPNHTLPTSGSARYASALGVETFMKHSSLIQYSPKALQKVAGAIDVLTKAEGLPSHGDSVRKRIKDGP
>NC_019693.1|WP_015151997.1|7597068_7597512_+|universal-stress-protein
MISTILVALDGSDLSEQVIATLHNLKLETMTQVILAHVISQPTSDLDVLADRPQVETEDIPYRVIEKKLQSYQEKIPCNTELEIVTGDPAEEIVRLANIYHADLILIGSRGLTGMKRILQGSVSSQVVTDASCSVLVVKPVLSVKGK
>NC_019693.1|WP_015151998.1|7597566_7597962_-|hypothetical-protein
MLGSFQQAHLRIEVDAPETVIRDSLLRRDRLQQWLWTQRFSTPLPEELHSGATFTISVGPLAVRHQVERADPNCLRLLLSGSIDGFHEWYWGDGWVQSRLEGVSLLPLNLSHTMNLLRLREFVAQTKAVSP

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_019693_1	1.1|132427|38|NC_019693|CRISPRCasFinder	132427-132464	38	NC_019693.1	278620-278657	0	1.0
NC_019693_1	1.1|132427|38|NC_019693|CRISPRCasFinder	132427-132464	38	NC_019693.1	3797870-3797907	0	1.0
NC_019693_1	1.1|132427|38|NC_019693|CRISPRCasFinder	132427-132464	38	NC_019693.1	6776038-6776075	0	1.0
NC_019693_1	1.1|132427|38|NC_019693|CRISPRCasFinder	132427-132464	38	NC_019693.1	1099603-1099640	0	1.0
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	1528903-1528932	0	1.0
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	2556886-2556915	0	1.0
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	4588114-4588143	0	1.0
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	6230735-6230764	0	1.0
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	6864921-6864950	0	1.0
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	6938928-6938957	0	1.0
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	832629-832658	0	1.0
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	2715862-2715891	0	1.0
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	4556376-4556405	0	1.0
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	6466023-6466052	0	1.0
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	7333754-7333783	0	1.0
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	7613898-7613927	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	110850-110884	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	388236-388270	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	440069-440103	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	691289-691323	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	1735643-1735677	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	2466362-2466396	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	2889623-2889657	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	2944747-2944781	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	2961312-2961346	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	3710899-3710933	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	3725289-3725323	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	3789277-3789311	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	4037366-4037400	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	4054117-4054151	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	4768645-4768679	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	4970167-4970201	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	4990488-4990522	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	5251975-5252009	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	6023800-6023834	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	6829811-6829845	0	1.0
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	7448315-7448349	0	1.0
NC_019693_25	25.1|2929334|42|NC_019693|CRISPRCasFinder	2929334-2929375	42	NC_019693.1	867568-867609	0	1.0
NC_019693_35	35.1|3942046|26|NC_019693|CRISPRCasFinder	3942046-3942071	26	NC_019693.1	184264-184289	0	1.0
NC_019693_35	35.1|3942046|26|NC_019693|CRISPRCasFinder	3942046-3942071	26	NC_019693.1	918874-918899	0	1.0
NC_019693_35	35.1|3942046|26|NC_019693|CRISPRCasFinder	3942046-3942071	26	NC_019693.1	985065-985090	0	1.0
NC_019693_35	35.1|3942046|26|NC_019693|CRISPRCasFinder	3942046-3942071	26	NC_019693.1	1182821-1182846	0	1.0
NC_019693_35	35.1|3942046|26|NC_019693|CRISPRCasFinder	3942046-3942071	26	NC_019693.1	1317768-1317793	0	1.0
NC_019693_35	35.1|3942046|26|NC_019693|CRISPRCasFinder	3942046-3942071	26	NC_019693.1	1779865-1779890	0	1.0
NC_019693_35	35.1|3942046|26|NC_019693|CRISPRCasFinder	3942046-3942071	26	NC_019693.1	1787734-1787759	0	1.0
NC_019693_35	35.1|3942046|26|NC_019693|CRISPRCasFinder	3942046-3942071	26	NC_019693.1	1885398-1885423	0	1.0
NC_019693_35	35.1|3942046|26|NC_019693|CRISPRCasFinder	3942046-3942071	26	NC_019693.1	1906376-1906401	0	1.0
NC_019693_35	35.1|3942046|26|NC_019693|CRISPRCasFinder	3942046-3942071	26	NC_019693.1	3895171-3895196	0	1.0
NC_019693_35	35.1|3942046|26|NC_019693|CRISPRCasFinder	3942046-3942071	26	NC_019693.1	4334686-4334711	0	1.0
NC_019693_35	35.1|3942046|26|NC_019693|CRISPRCasFinder	3942046-3942071	26	NC_019693.1	4408555-4408580	0	1.0
NC_019693_35	35.1|3942046|26|NC_019693|CRISPRCasFinder	3942046-3942071	26	NC_019693.1	5419798-5419823	0	1.0
NC_019693_35	35.1|3942046|26|NC_019693|CRISPRCasFinder	3942046-3942071	26	NC_019693.1	5609619-5609644	0	1.0
NC_019693_35	35.1|3942046|26|NC_019693|CRISPRCasFinder	3942046-3942071	26	NC_019693.1	5928772-5928797	0	1.0
NC_019693_35	35.1|3942046|26|NC_019693|CRISPRCasFinder	3942046-3942071	26	NC_019693.1	6989857-6989882	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	110850-110884	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	388236-388270	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	440069-440103	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	691289-691323	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	1735643-1735677	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	2466362-2466396	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	2889623-2889657	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	2944747-2944781	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	2961312-2961346	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	3710899-3710933	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	3725289-3725323	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	3789277-3789311	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	4037366-4037400	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	4054117-4054151	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	4768645-4768679	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	4970167-4970201	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	4990488-4990522	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	5251975-5252009	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	6023800-6023834	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	6829811-6829845	0	1.0
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	7448315-7448349	0	1.0
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_019693.1	1725578-1725602	0	1.0
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_019693.1	161652-161676	0	1.0
NC_019693_54	54.1|5228825|28|NC_019693|CRT	5228825-5228852	28	NC_019693.1	5229069-5229096	0	1.0
NC_019693_54	54.2|5228890|20|NC_019693|CRT	5228890-5228909	20	NC_019693.1	5229077-5229096	0	1.0
NC_019693_54	54.4|5229012|20|NC_019693|CRT	5229012-5229031	20	NC_019693.1	5229077-5229096	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	110852-110884	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	440071-440103	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	691291-691323	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	2889625-2889657	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	3725291-3725323	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	3789279-3789311	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	4037368-4037400	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	4990490-4990522	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	5251977-5252009	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	6829813-6829845	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	388236-388268	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	1735643-1735675	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	2466362-2466394	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	2944747-2944779	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	2961312-2961344	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	3710899-3710931	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	4054117-4054149	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	4768645-4768677	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	4970167-4970199	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	6023800-6023832	0	1.0
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	7448315-7448347	0	1.0
NC_019693_62	62.2|5697975|39|NC_019693|CRISPRCasFinder	5697975-5698013	39	NC_019693.1	6792251-6792289	0	1.0
NC_019693_62	62.2|5697975|39|NC_019693|CRISPRCasFinder	5697975-5698013	39	NC_019693.1	5698037-5698075	0	1.0
NC_019693_62	62.2|5697975|39|NC_019693|CRISPRCasFinder	5697975-5698013	39	NC_019693.1	5857011-5857049	0	1.0
NC_019693_62	62.2|5697975|39|NC_019693|CRISPRCasFinder	5697975-5698013	39	NC_019693.1	6104207-6104245	0	1.0
NC_019693_75	75.34|7041365|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7041365-7041400	36	NC_019693.1	508679-508714	0	1.0
NC_019693_1	1.1|132427|38|NC_019693|CRISPRCasFinder	132427-132464	38	NC_019693.1	6334302-6334339	1	0.974
NC_019693_1	1.1|132427|38|NC_019693|CRISPRCasFinder	132427-132464	38	NC_019693.1	6814107-6814144	1	0.974
NC_019693_1	1.1|132427|38|NC_019693|CRISPRCasFinder	132427-132464	38	NC_019693.1	6999939-6999976	1	0.974
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	161636-161665	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	180766-180795	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	222688-222717	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	634551-634580	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	768507-768536	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	832295-832324	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	1082515-1082544	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	1193440-1193469	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	1745317-1745346	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	1906154-1906183	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	2426109-2426138	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	2609226-2609255	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	2715631-2715660	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	3271553-3271582	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	3928616-3928645	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	3950023-3950052	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	3950147-3950176	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	4187201-4187230	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	4198596-4198625	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	4556146-4556175	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	4951819-4951848	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	5101082-5101111	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	5357282-5357311	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	5572298-5572327	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	5609480-5609509	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	5690120-5690149	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	5690192-5690221	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	6465871-6465900	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	6716256-6716285	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	6870700-6870729	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	7239326-7239355	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	7306049-7306078	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	7333429-7333458	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	161838-161867	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	187709-187738	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	222906-222935	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	634761-634790	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	809668-809697	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	809783-809812	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	809897-809926	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	1193641-1193670	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	1482097-1482126	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	1518032-1518061	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	2426346-2426375	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	2611326-2611355	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	2955523-2955552	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	3558393-3558422	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	3564423-3564452	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	4187608-4187637	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	4620364-4620393	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	4620419-4620448	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	4756686-4756715	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	5039718-5039747	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	5575164-5575193	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	5609849-5609878	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	5615690-5615719	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	6095800-6095829	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	6377677-6377706	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	6615348-6615377	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	6716457-6716486	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	7444825-7444854	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	7478583-7478612	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	7479560-7479589	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	7502479-7502508	1	0.967
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	7502560-7502589	1	0.967
NC_019693_8	8.1|291886|35|NC_019693|CRISPRCasFinder	291886-291920	35	NC_019693.1	3079057-3079091	1	0.971
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	388236-388268	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	1735643-1735675	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	2466362-2466394	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	2944747-2944779	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	2961312-2961344	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	3710899-3710931	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	4054117-4054149	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	4768645-4768677	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	4970167-4970199	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	6023800-6023832	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	7448315-7448347	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	110852-110884	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	440071-440103	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	691291-691323	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	2889625-2889657	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	3725291-3725323	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	3789279-3789311	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	4037368-4037400	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	4990490-4990522	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	5251977-5252009	1	0.97
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	6829813-6829845	1	0.97
NC_019693_45	45.1|4744712|35|NC_019693|CRISPRCasFinder	4744712-4744746	35	NC_019693.1	3079057-3079091	1	0.971
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	4378256-4378288	1	0.97
NC_019693_60	60.1|5593147|33|NC_019693|CRISPRCasFinder	5593147-5593179	33	NC_019693.1	3079057-3079089	1	0.97
NC_019693_62	62.2|5697975|39|NC_019693|CRISPRCasFinder	5697975-5698013	39	NC_019693.1	1099740-1099778	1	0.974
NC_019693_62	62.2|5697975|39|NC_019693|CRISPRCasFinder	5697975-5698013	39	NC_019693.1	2435060-2435098	1	0.974
NC_019693_62	62.2|5697975|39|NC_019693|CRISPRCasFinder	5697975-5698013	39	NC_019693.1	6658417-6658455	1	0.974
NC_019693_62	62.2|5697975|39|NC_019693|CRISPRCasFinder	5697975-5698013	39	NC_019693.1	5213650-5213688	1	0.974
NC_019693_62	62.2|5697975|39|NC_019693|CRISPRCasFinder	5697975-5698013	39	NC_019693.1	7078917-7078955	1	0.974
NC_019693_1	1.1|132427|38|NC_019693|CRISPRCasFinder	132427-132464	38	NC_019693.1	14322-14359	2	0.947
NC_019693_1	1.1|132427|38|NC_019693|CRISPRCasFinder	132427-132464	38	NC_019693.1	4221706-4221743	2	0.947
NC_019693_1	1.1|132427|38|NC_019693|CRISPRCasFinder	132427-132464	38	NC_019693.1	3145509-3145546	2	0.947
NC_019693_1	1.1|132427|38|NC_019693|CRISPRCasFinder	132427-132464	38	NC_019693.1	4664435-4664472	2	0.947
NC_019693_1	1.1|132427|38|NC_019693|CRISPRCasFinder	132427-132464	38	NC_019693.1	7319734-7319771	2	0.947
NC_019693_2	2.1|154608|27|NC_019693|CRISPRCasFinder	154608-154634	27	NC_019693.1	4408517-4408543	2	0.926
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	3950085-3950114	2	0.933
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	6291327-6291356	2	0.933
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	1468374-1468403	2	0.933
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	1725589-1725618	2	0.933
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	4611303-4611332	2	0.933
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	5938094-5938123	2	0.933
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NC_019693.1	6157597-6157626	2	0.933
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	3079057-3079089	2	0.939
NC_019693_34	34.1|3928797|33|NC_019693|CRISPRCasFinder	3928797-3928829	33	NC_019693.1	4378256-4378288	2	0.939
NC_019693_62	62.2|5697975|39|NC_019693|CRISPRCasFinder	5697975-5698013	39	NC_019693.1	4032884-4032922	2	0.949
NC_019693_62	62.2|5697975|39|NC_019693|CRISPRCasFinder	5697975-5698013	39	NC_019693.1	1802696-1802734	2	0.949
NC_019693_62	62.2|5697975|39|NC_019693|CRISPRCasFinder	5697975-5698013	39	NC_019693.1	6122571-6122609	2	0.949

1. spacer 1.1|132427|38|NC_019693|CRISPRCasFinder matches to position: 278620-278657, mismatch: 0, identity: 1.0

ttcttagcccgcgcaggcgggcttcgtccgtatagccc	CRISPR spacer
ttcttagcccgcgcaggcgggcttcgtccgtatagccc	Protospacer
**************************************

2. spacer 1.1|132427|38|NC_019693|CRISPRCasFinder matches to position: 3797870-3797907, mismatch: 0, identity: 1.0

ttcttagcccgcgcaggcgggcttcgtccgtatagccc	CRISPR spacer
ttcttagcccgcgcaggcgggcttcgtccgtatagccc	Protospacer
**************************************

3. spacer 1.1|132427|38|NC_019693|CRISPRCasFinder matches to position: 6776038-6776075, mismatch: 0, identity: 1.0

ttcttagcccgcgcaggcgggcttcgtccgtatagccc	CRISPR spacer
ttcttagcccgcgcaggcgggcttcgtccgtatagccc	Protospacer
**************************************

4. spacer 1.1|132427|38|NC_019693|CRISPRCasFinder matches to position: 1099603-1099640, mismatch: 0, identity: 1.0

ttcttagcccgcgcaggcgggcttcgtccgtatagccc	CRISPR spacer
ttcttagcccgcgcaggcgggcttcgtccgtatagccc	Protospacer
**************************************

5. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 1528903-1528932, mismatch: 0, identity: 1.0

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttagcaaggggagggtt	Protospacer
******************************

6. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 2556886-2556915, mismatch: 0, identity: 1.0

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttagcaaggggagggtt	Protospacer
******************************

7. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 4588114-4588143, mismatch: 0, identity: 1.0

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttagcaaggggagggtt	Protospacer
******************************

8. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 6230735-6230764, mismatch: 0, identity: 1.0

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttagcaaggggagggtt	Protospacer
******************************

9. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 6864921-6864950, mismatch: 0, identity: 1.0

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttagcaaggggagggtt	Protospacer
******************************

10. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 6938928-6938957, mismatch: 0, identity: 1.0

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttagcaaggggagggtt	Protospacer
******************************

11. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 832629-832658, mismatch: 0, identity: 1.0

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttagcaaggggagggtt	Protospacer
******************************

12. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 2715862-2715891, mismatch: 0, identity: 1.0

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttagcaaggggagggtt	Protospacer
******************************

13. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 4556376-4556405, mismatch: 0, identity: 1.0

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttagcaaggggagggtt	Protospacer
******************************

14. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 6466023-6466052, mismatch: 0, identity: 1.0

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttagcaaggggagggtt	Protospacer
******************************

15. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 7333754-7333783, mismatch: 0, identity: 1.0

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttagcaaggggagggtt	Protospacer
******************************

16. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 7613898-7613927, mismatch: 0, identity: 1.0

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttagcaaggggagggtt	Protospacer
******************************

17. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 110850-110884, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

18. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 388236-388270, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

19. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 440069-440103, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

20. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 691289-691323, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

21. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 1735643-1735677, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

22. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 2466362-2466396, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

23. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 2889623-2889657, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

24. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 2944747-2944781, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

25. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 2961312-2961346, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

26. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 3710899-3710933, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

27. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 3725289-3725323, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

28. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 3789277-3789311, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

29. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 4037366-4037400, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

30. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 4054117-4054151, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

31. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 4768645-4768679, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

32. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 4970167-4970201, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

33. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 4990488-4990522, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

34. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 5251975-5252009, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

35. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 6023800-6023834, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

36. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 6829811-6829845, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

37. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 7448315-7448349, mismatch: 0, identity: 1.0

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgcctgtc	Protospacer
***********************************

38. spacer 25.1|2929334|42|NC_019693|CRISPRCasFinder matches to position: 867568-867609, mismatch: 0, identity: 1.0

tcttggacaggcgatcactctcgcgcccctacaagaaataag	CRISPR spacer
tcttggacaggcgatcactctcgcgcccctacaagaaataag	Protospacer
******************************************

39. spacer 35.1|3942046|26|NC_019693|CRISPRCasFinder matches to position: 184264-184289, mismatch: 0, identity: 1.0

ctgcgcattgcgcccctacaagaaac	CRISPR spacer
ctgcgcattgcgcccctacaagaaac	Protospacer
**************************

40. spacer 35.1|3942046|26|NC_019693|CRISPRCasFinder matches to position: 918874-918899, mismatch: 0, identity: 1.0

ctgcgcattgcgcccctacaagaaac	CRISPR spacer
ctgcgcattgcgcccctacaagaaac	Protospacer
**************************

41. spacer 35.1|3942046|26|NC_019693|CRISPRCasFinder matches to position: 985065-985090, mismatch: 0, identity: 1.0

ctgcgcattgcgcccctacaagaaac	CRISPR spacer
ctgcgcattgcgcccctacaagaaac	Protospacer
**************************

42. spacer 35.1|3942046|26|NC_019693|CRISPRCasFinder matches to position: 1182821-1182846, mismatch: 0, identity: 1.0

ctgcgcattgcgcccctacaagaaac	CRISPR spacer
ctgcgcattgcgcccctacaagaaac	Protospacer
**************************

43. spacer 35.1|3942046|26|NC_019693|CRISPRCasFinder matches to position: 1317768-1317793, mismatch: 0, identity: 1.0

ctgcgcattgcgcccctacaagaaac	CRISPR spacer
ctgcgcattgcgcccctacaagaaac	Protospacer
**************************

44. spacer 35.1|3942046|26|NC_019693|CRISPRCasFinder matches to position: 1779865-1779890, mismatch: 0, identity: 1.0

ctgcgcattgcgcccctacaagaaac	CRISPR spacer
ctgcgcattgcgcccctacaagaaac	Protospacer
**************************

45. spacer 35.1|3942046|26|NC_019693|CRISPRCasFinder matches to position: 1787734-1787759, mismatch: 0, identity: 1.0

ctgcgcattgcgcccctacaagaaac	CRISPR spacer
ctgcgcattgcgcccctacaagaaac	Protospacer
**************************

46. spacer 35.1|3942046|26|NC_019693|CRISPRCasFinder matches to position: 1885398-1885423, mismatch: 0, identity: 1.0

ctgcgcattgcgcccctacaagaaac	CRISPR spacer
ctgcgcattgcgcccctacaagaaac	Protospacer
**************************

47. spacer 35.1|3942046|26|NC_019693|CRISPRCasFinder matches to position: 1906376-1906401, mismatch: 0, identity: 1.0

ctgcgcattgcgcccctacaagaaac	CRISPR spacer
ctgcgcattgcgcccctacaagaaac	Protospacer
**************************

48. spacer 35.1|3942046|26|NC_019693|CRISPRCasFinder matches to position: 3895171-3895196, mismatch: 0, identity: 1.0

ctgcgcattgcgcccctacaagaaac	CRISPR spacer
ctgcgcattgcgcccctacaagaaac	Protospacer
**************************

49. spacer 35.1|3942046|26|NC_019693|CRISPRCasFinder matches to position: 4334686-4334711, mismatch: 0, identity: 1.0

ctgcgcattgcgcccctacaagaaac	CRISPR spacer
ctgcgcattgcgcccctacaagaaac	Protospacer
**************************

50. spacer 35.1|3942046|26|NC_019693|CRISPRCasFinder matches to position: 4408555-4408580, mismatch: 0, identity: 1.0

ctgcgcattgcgcccctacaagaaac	CRISPR spacer
ctgcgcattgcgcccctacaagaaac	Protospacer
**************************

51. spacer 35.1|3942046|26|NC_019693|CRISPRCasFinder matches to position: 5419798-5419823, mismatch: 0, identity: 1.0

ctgcgcattgcgcccctacaagaaac	CRISPR spacer
ctgcgcattgcgcccctacaagaaac	Protospacer
**************************

52. spacer 35.1|3942046|26|NC_019693|CRISPRCasFinder matches to position: 5609619-5609644, mismatch: 0, identity: 1.0

ctgcgcattgcgcccctacaagaaac	CRISPR spacer
ctgcgcattgcgcccctacaagaaac	Protospacer
**************************

53. spacer 35.1|3942046|26|NC_019693|CRISPRCasFinder matches to position: 5928772-5928797, mismatch: 0, identity: 1.0

ctgcgcattgcgcccctacaagaaac	CRISPR spacer
ctgcgcattgcgcccctacaagaaac	Protospacer
**************************

54. spacer 35.1|3942046|26|NC_019693|CRISPRCasFinder matches to position: 6989857-6989882, mismatch: 0, identity: 1.0

ctgcgcattgcgcccctacaagaaac	CRISPR spacer
ctgcgcattgcgcccctacaagaaac	Protospacer
**************************

55. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 110850-110884, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

56. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 388236-388270, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

57. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 440069-440103, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

58. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 691289-691323, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

59. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 1735643-1735677, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

60. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 2466362-2466396, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

61. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 2889623-2889657, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

62. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 2944747-2944781, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

63. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 2961312-2961346, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

64. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 3710899-3710933, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

65. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 3725289-3725323, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

66. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 3789277-3789311, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

67. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 4037366-4037400, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

68. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 4054117-4054151, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

69. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 4768645-4768679, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

70. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 4970167-4970201, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

71. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 4990488-4990522, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

72. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 5251975-5252009, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

73. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 6023800-6023834, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

74. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 6829811-6829845, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

75. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 7448315-7448349, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagaggta	Protospacer
***********************************

76. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to position: 1725578-1725602, mismatch: 0, identity: 1.0

aaccccaccctaaccctccccttgg	CRISPR spacer
aaccccaccctaaccctccccttgg	Protospacer
*************************

77. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to position: 161652-161676, mismatch: 0, identity: 1.0

aaccccaccctaaccctccccttgg	CRISPR spacer
aaccccaccctaaccctccccttgg	Protospacer
*************************

78. spacer 54.1|5228825|28|NC_019693|CRT matches to position: 5229069-5229096, mismatch: 0, identity: 1.0

ttggggtcattaaattgaacacctgtcc	CRISPR spacer
ttggggtcattaaattgaacacctgtcc	Protospacer
****************************

79. spacer 54.2|5228890|20|NC_019693|CRT matches to position: 5229077-5229096, mismatch: 0, identity: 1.0

attaaattgaacacctgtcc	CRISPR spacer
attaaattgaacacctgtcc	Protospacer
********************

80. spacer 54.4|5229012|20|NC_019693|CRT matches to position: 5229077-5229096, mismatch: 0, identity: 1.0

attaaattgaacacctgtcc	CRISPR spacer
attaaattgaacacctgtcc	Protospacer
********************

81. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 110852-110884, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

82. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 440071-440103, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

83. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 691291-691323, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

84. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 2889625-2889657, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

85. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 3725291-3725323, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

86. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 3789279-3789311, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

87. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 4037368-4037400, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

88. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 4990490-4990522, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

89. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 5251977-5252009, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

90. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 6829813-6829845, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

91. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 388236-388268, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

92. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 1735643-1735675, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

93. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 2466362-2466394, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

94. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 2944747-2944779, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

95. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 2961312-2961344, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

96. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 3710899-3710931, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

97. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 4054117-4054149, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

98. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 4768645-4768677, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

99. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 4970167-4970199, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

100. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 6023800-6023832, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

101. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 7448315-7448347, mismatch: 0, identity: 1.0

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
*********************************

102. spacer 62.2|5697975|39|NC_019693|CRISPRCasFinder matches to position: 6792251-6792289, mismatch: 0, identity: 1.0

atcagagggcgtatgcaatacgcccctacaaatacacct	CRISPR spacer
atcagagggcgtatgcaatacgcccctacaaatacacct	Protospacer
***************************************

103. spacer 62.2|5697975|39|NC_019693|CRISPRCasFinder matches to position: 5698037-5698075, mismatch: 0, identity: 1.0

atcagagggcgtatgcaatacgcccctacaaatacacct	CRISPR spacer
atcagagggcgtatgcaatacgcccctacaaatacacct	Protospacer
***************************************

104. spacer 62.2|5697975|39|NC_019693|CRISPRCasFinder matches to position: 5857011-5857049, mismatch: 0, identity: 1.0

atcagagggcgtatgcaatacgcccctacaaatacacct	CRISPR spacer
atcagagggcgtatgcaatacgcccctacaaatacacct	Protospacer
***************************************

105. spacer 62.2|5697975|39|NC_019693|CRISPRCasFinder matches to position: 6104207-6104245, mismatch: 0, identity: 1.0

atcagagggcgtatgcaatacgcccctacaaatacacct	CRISPR spacer
atcagagggcgtatgcaatacgcccctacaaatacacct	Protospacer
***************************************

106. spacer 75.34|7041365|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to position: 508679-508714, mismatch: 0, identity: 1.0

tttgtcttacccgacagagatgattaatcgccatga	CRISPR spacer
tttgtcttacccgacagagatgattaatcgccatga	Protospacer
************************************

107. spacer 1.1|132427|38|NC_019693|CRISPRCasFinder matches to position: 6334302-6334339, mismatch: 1, identity: 0.974

ttcttagcccgcgcaggcgggcttcgtccgtatagccc	CRISPR spacer
ttcttagcccgcgcaggcgggcttcgtccgtgtagccc	Protospacer
*******************************.******

108. spacer 1.1|132427|38|NC_019693|CRISPRCasFinder matches to position: 6814107-6814144, mismatch: 1, identity: 0.974

ttcttagcccgcgcaggcgggcttcgtccgtatagccc	CRISPR spacer
ttcttagcccgcgcaggcgggctttgtccgtatagccc	Protospacer
************************.*************

109. spacer 1.1|132427|38|NC_019693|CRISPRCasFinder matches to position: 6999939-6999976, mismatch: 1, identity: 0.974

ttcttagcccgcgcaggcgggcttcgtccgtatagccc	CRISPR spacer
ttcttagcccgcgcaggcgggcttcgtccgtgtagccc	Protospacer
*******************************.******

110. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 161636-161665, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttaccaaggggagggtt	Protospacer
**************** *************

111. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 180766-180795, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

112. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 222688-222717, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

113. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 634551-634580, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

114. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 768507-768536, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

115. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 832295-832324, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

116. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 1082515-1082544, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

117. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 1193440-1193469, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

118. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 1745317-1745346, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

119. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 1906154-1906183, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttagcaaggagagggtt	Protospacer
**********************.*******

120. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 2426109-2426138, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

121. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 2609226-2609255, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

122. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 2715631-2715660, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

123. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 3271553-3271582, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttagcaagggtagggtt	Protospacer
*********************** ******

124. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 3928616-3928645, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

125. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 3950023-3950052, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

126. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 3950147-3950176, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

127. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 4187201-4187230, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

128. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 4198596-4198625, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

129. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 4556146-4556175, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

130. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 4951819-4951848, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

131. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 5101082-5101111, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

132. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 5357282-5357311, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

133. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 5572298-5572327, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

134. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 5609480-5609509, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

135. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 5690120-5690149, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

136. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 5690192-5690221, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

137. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 6465871-6465900, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

138. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 6716256-6716285, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

139. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 6870700-6870729, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

140. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 7239326-7239355, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

141. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 7306049-7306078, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

142. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 7333429-7333458, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

143. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 161838-161867, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

144. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 187709-187738, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

145. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 222906-222935, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

146. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 634761-634790, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

147. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 809668-809697, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

148. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 809783-809812, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

149. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 809897-809926, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

150. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 1193641-1193670, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

151. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 1482097-1482126, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

152. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 1518032-1518061, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

153. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 2426346-2426375, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

154. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 2611326-2611355, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

155. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 2955523-2955552, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

156. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 3558393-3558422, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

157. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 3564423-3564452, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

158. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 4187608-4187637, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

159. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 4620364-4620393, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

160. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 4620419-4620448, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

161. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 4756686-4756715, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

162. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 5039718-5039747, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

163. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 5575164-5575193, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

164. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 5609849-5609878, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggttccctccccttagcaaggggagggtt	Protospacer
****.*************************

165. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 5615690-5615719, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

166. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 6095800-6095829, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

167. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 6377677-6377706, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

168. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 6615348-6615377, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

169. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 6716457-6716486, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

170. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 7444825-7444854, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

171. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 7478583-7478612, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

172. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 7479560-7479589, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

173. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 7502479-7502508, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

174. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 7502560-7502589, mismatch: 1, identity: 0.967

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttggcaaggggagggtt	Protospacer
***************.**************

175. spacer 8.1|291886|35|NC_019693|CRISPRCasFinder matches to position: 3079057-3079091, mismatch: 1, identity: 0.971

tacctcttgtaggggcgcgagagtgatcgcctgtc	CRISPR spacer
tacctcttgtaggggcgcgagagtgatcgccggtc	Protospacer
******************************* ***

176. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 388236-388268, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

177. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 1735643-1735675, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

178. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 2466362-2466394, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

179. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 2944747-2944779, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

180. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 2961312-2961344, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

181. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 3710899-3710931, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

182. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 4054117-4054149, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

183. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 4768645-4768677, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

184. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 4970167-4970199, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

185. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 6023800-6023832, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

186. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 7448315-7448347, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

187. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 110852-110884, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

188. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 440071-440103, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

189. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 691291-691323, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

190. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 2889625-2889657, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

191. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 3725291-3725323, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

192. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 3789279-3789311, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

193. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 4037368-4037400, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

194. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 4990490-4990522, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

195. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 5251977-5252009, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

196. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 6829813-6829845, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gacaggcgatcactctcgcgcccctacaagagg	Protospacer
******************** ************

197. spacer 45.1|4744712|35|NC_019693|CRISPRCasFinder matches to position: 3079057-3079091, mismatch: 1, identity: 0.971

gacaggcgatcactctcgcgcccctacaagaggta	CRISPR spacer
gaccggcgatcactctcgcgcccctacaagaggta	Protospacer
*** *******************************

198. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 4378256-4378288, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gaccggcgatcactctcgcgcccctacaagagg	Protospacer
*** *****************************

199. spacer 60.1|5593147|33|NC_019693|CRISPRCasFinder matches to position: 3079057-3079089, mismatch: 1, identity: 0.97

gacaggcgatcactctcgcgcccctacaagagg	CRISPR spacer
gaccggcgatcactctcgcgcccctacaagagg	Protospacer
*** *****************************

200. spacer 62.2|5697975|39|NC_019693|CRISPRCasFinder matches to position: 1099740-1099778, mismatch: 1, identity: 0.974

atcagagggcgtatgcaatacgcccctacaaatacacct	CRISPR spacer
atgagagggcgtatgcaatacgcccctacaaatacacct	Protospacer
** ************************************

201. spacer 62.2|5697975|39|NC_019693|CRISPRCasFinder matches to position: 2435060-2435098, mismatch: 1, identity: 0.974

atcagagggcgtatgcaatacgcccctacaaatacacct	CRISPR spacer
atgagagggcgtatgcaatacgcccctacaaatacacct	Protospacer
** ************************************

202. spacer 62.2|5697975|39|NC_019693|CRISPRCasFinder matches to position: 6658417-6658455, mismatch: 1, identity: 0.974

atcagagggcgtatgcaatacgcccctacaaatacacct	CRISPR spacer
atgagagggcgtatgcaatacgcccctacaaatacacct	Protospacer
** ************************************

203. spacer 62.2|5697975|39|NC_019693|CRISPRCasFinder matches to position: 5213650-5213688, mismatch: 1, identity: 0.974

atcagagggcgtatgcaatacgcccctacaaatacacct	CRISPR spacer
atgagagggcgtatgcaatacgcccctacaaatacacct	Protospacer
** ************************************

204. spacer 62.2|5697975|39|NC_019693|CRISPRCasFinder matches to position: 7078917-7078955, mismatch: 1, identity: 0.974

atcagagggcgtatgcaatacgcccctacaaatacacct	CRISPR spacer
ataagagggcgtatgcaatacgcccctacaaatacacct	Protospacer
** ************************************

205. spacer 1.1|132427|38|NC_019693|CRISPRCasFinder matches to position: 14322-14359, mismatch: 2, identity: 0.947

ttcttagcccgcgcaggcgggcttcgtccgtatagccc	CRISPR spacer
ttcttagcccgcgcaggcgggctttgtccgtgtagccc	Protospacer
************************.******.******

206. spacer 1.1|132427|38|NC_019693|CRISPRCasFinder matches to position: 4221706-4221743, mismatch: 2, identity: 0.947

ttcttagcccgcgcaggcgggcttcgtccgtatagccc	CRISPR spacer
ttcttagcccgcgcaggcgggctttgttcgtatagccc	Protospacer
************************.**.**********

207. spacer 1.1|132427|38|NC_019693|CRISPRCasFinder matches to position: 3145509-3145546, mismatch: 2, identity: 0.947

ttcttagcccgcgcaggcgggcttcgtccgtatagccc	CRISPR spacer
tttttagcccgcgcaggcgggcttcgttcgtatagccc	Protospacer
**.************************.**********

208. spacer 1.1|132427|38|NC_019693|CRISPRCasFinder matches to position: 4664435-4664472, mismatch: 2, identity: 0.947

ttcttagcccgcgcaggcgggcttcgtccgtatagccc	CRISPR spacer
ttcttagcccgcgcaggcgggcttcgttcgtgtagccc	Protospacer
***************************.***.******

209. spacer 1.1|132427|38|NC_019693|CRISPRCasFinder matches to position: 7319734-7319771, mismatch: 2, identity: 0.947

ttcttagcccgcgcaggcgggcttcgtccgtatagccc	CRISPR spacer
ttcttagcccgcgcaggcgggctttgtccgtgtagccc	Protospacer
************************.******.******

210. spacer 2.1|154608|27|NC_019693|CRISPRCasFinder matches to position: 4408517-4408543, mismatch: 2, identity: 0.926

gccctctttatccctccattgaatccc	CRISPR spacer
gccctctttatccctcaatcgaatccc	Protospacer
**************** **.*******

211. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 3950085-3950114, mismatch: 2, identity: 0.933

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggttccctccccttggcaaggggagggtt	Protospacer
****.**********.**************

212. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 6291327-6291356, mismatch: 2, identity: 0.933

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggttccctccccttggcaaggggagggtt	Protospacer
****.**********.**************

213. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 1468374-1468403, mismatch: 2, identity: 0.933

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttgccaaggggagggtt	Protospacer
***************. *************

214. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 1725589-1725618, mismatch: 2, identity: 0.933

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttgccaaggggagggtt	Protospacer
***************. *************

215. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 4611303-4611332, mismatch: 2, identity: 0.933

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggtcccctccccttgccaaggggagggtt	Protospacer
***************. *************

216. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 5938094-5938123, mismatch: 2, identity: 0.933

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggttccctccccttggcaaggggagggtt	Protospacer
****.**********.**************

217. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to position: 6157597-6157626, mismatch: 2, identity: 0.933

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
cggttccctcccctttgcaaggggagggtt	Protospacer
****.********** **************

218. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 3079057-3079089, mismatch: 2, identity: 0.939

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gaccggcgatcactctcgcgcccctacaagagg	Protospacer
*** **************** ************

219. spacer 34.1|3928797|33|NC_019693|CRISPRCasFinder matches to position: 4378256-4378288, mismatch: 2, identity: 0.939

gacaggcgatcactctcgcggccctacaagagg	CRISPR spacer
gaccggcgatcactctcgcgcccctacaagagg	Protospacer
*** **************** ************

220. spacer 62.2|5697975|39|NC_019693|CRISPRCasFinder matches to position: 4032884-4032922, mismatch: 2, identity: 0.949

atcagagggcgtatgcaatacgcccctacaaatacacct	CRISPR spacer
atgagagggcgtatgcaatacgcccctacgaatacacct	Protospacer
** **************************.*********

221. spacer 62.2|5697975|39|NC_019693|CRISPRCasFinder matches to position: 1802696-1802734, mismatch: 2, identity: 0.949

atcagagggcgtatgcaatacgcccctacaaatacacct	CRISPR spacer
atcagatggcgtatgcaatacgcccctacaaatatacct	Protospacer
****** ***************************.****

222. spacer 62.2|5697975|39|NC_019693|CRISPRCasFinder matches to position: 6122571-6122609, mismatch: 2, identity: 0.949

atcagagggcgtatgcaatacgcccctacaaatacacct	CRISPR spacer
ataagagggcgtatgcaatccgcccctacaaatacacct	Protospacer
** **************** *******************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	130802-130826	2	0.92
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP043057	Dolichospermum sp. UHCC 0315A plasmid pUHCC0315a, complete sequence	94316-94340	2	0.92
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP043059	Dolichospermum sp. UHCC 0315A plasmid pUHCC0315c, complete sequence	29235-29259	2	0.92
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_AP017564	Pseudanabaena sp. ABRG5-3 plasmid ABRG53d, complete sequence	36912-36936	2	0.92
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_AP017564	Pseudanabaena sp. ABRG5-3 plasmid ABRG53d, complete sequence	51078-51102	2	0.92
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_AP017564	Pseudanabaena sp. ABRG5-3 plasmid ABRG53d, complete sequence	32933-32957	2	0.92
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_AP017383	Moraxella osloensis strain KMC41 plasmid pMOSL2, complete sequence	34870-34894	2	0.92
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP024183	Moraxella osloensis strain KSH plasmid p3, complete sequence	29970-29994	2	0.92
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP024447	Moraxella osloensis strain NP7 plasmid pNP7-4, complete sequence	19714-19738	2	0.92
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP024792	Nostoc flagelliforme CCNUN1 plasmid pNFSY07, complete sequence	91869-91893	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054609	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed1, complete sequence	443981-444005	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	1073069-1073093	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	324037-324061	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP036488	Rahnella aquatilis strain MEM40 plasmid pMEM40-1, complete sequence	86660-86684	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP036488	Rahnella aquatilis strain MEM40 plasmid pMEM40-1, complete sequence	120205-120229	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP036488	Rahnella aquatilis strain MEM40 plasmid pMEM40-1, complete sequence	351167-351191	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032297	Rahnella aquatilis strain ZF7 plasmid pRAZF7, complete sequence	214192-214216	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032297	Rahnella aquatilis strain ZF7 plasmid pRAZF7, complete sequence	449075-449099	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032297	Rahnella aquatilis strain ZF7 plasmid pRAZF7, complete sequence	482624-482648	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_017060	Rahnella aquatilis HX2 plasmid PRA1, complete sequence	162609-162633	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_017060	Rahnella aquatilis HX2 plasmid PRA1, complete sequence	196167-196191	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_017060	Rahnella aquatilis HX2 plasmid PRA1, complete sequence	439238-439262	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_017588	Thermus thermophilus JL-18 plasmid pTTJL1801, complete sequence	171039-171063	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP034838	Rahnella aquatilis strain KM12 plasmid pKM12v1, complete sequence	151992-152016	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP034838	Rahnella aquatilis strain KM12 plasmid pKM12v1, complete sequence	185542-185566	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP034838	Rahnella aquatilis strain KM12 plasmid pKM12v1, complete sequence	424260-424284	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP034838	Rahnella aquatilis strain KM12 plasmid pKM12v1, complete sequence	426879-426903	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP034839	Rahnella aquatilis strain KM25 plasmid pKM12v2, complete sequence	151992-152016	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP034839	Rahnella aquatilis strain KM25 plasmid pKM12v2, complete sequence	185542-185566	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP034839	Rahnella aquatilis strain KM25 plasmid pKM12v2, complete sequence	424260-424284	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP034839	Rahnella aquatilis strain KM25 plasmid pKM12v2, complete sequence	426879-426903	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP034837	Rahnella aquatilis strain KM05 plasmid pKM05, complete sequence	112317-112341	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP034837	Rahnella aquatilis strain KM05 plasmid pKM05, complete sequence	145866-145890	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP034837	Rahnella aquatilis strain KM05 plasmid pKM05, complete sequence	380767-380791	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_015062	Rahnella sp. Y9602 plasmid pRAHAQ01, complete sequence	199352-199376	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_015062	Rahnella sp. Y9602 plasmid pRAHAQ01, complete sequence	165792-165816	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP024186	Moraxella osloensis strain TT16 plasmid p1, complete sequence	54080-54104	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP024177	Moraxella osloensis strain YHS plasmid pYHS1, complete sequence	54048-54072	3	0.88
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	1655155-1655179	4	0.84
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	2352768-2352792	4	0.84
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1144060-1144084	4	0.84
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_008608	Pelobacter propionicus DSM 2379 plasmid pPRO2, complete sequence	14768-14792	4	0.84
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP033227	Sphingobium yanoikuyae strain SJTF8 plasmid pF1, complete sequence	331905-331929	4	0.84
NC_019693_56	56.1|5530383|25|NC_019693|CRISPRCasFinder	5530383-5530407	25	MK490927	Phage Altai3, complete genome	24854-24878	4	0.84
NC_019693_4	4.1|222750|30|NC_019693|CRISPRCasFinder	222750-222779	30	NZ_AP017564	Pseudanabaena sp. ABRG5-3 plasmid ABRG53d, complete sequence	51089-51118	5	0.833
NC_019693_33	33.1|3787169|27|NC_019693|CRISPRCasFinder	3787169-3787195	27	NC_014827	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL04, complete sequence	3921-3947	5	0.815
NC_019693_33	33.1|3787169|27|NC_019693|CRISPRCasFinder	3787169-3787195	27	NC_014827	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL04, complete sequence	3988-4014	5	0.815
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	1511642-1511666	5	0.8
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	2344267-2344291	5	0.8
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1376600-1376624	5	0.8
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	482086-482110	5	0.8
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	88397-88421	5	0.8
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1019418-1019442	5	0.8
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1631892-1631916	5	0.8
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022369	Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence	154037-154061	5	0.8
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	624632-624656	5	0.8
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	80814-80838	5	0.8
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	574734-574758	5	0.8
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	85961-85985	5	0.8
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	356214-356238	5	0.8
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	356240-356264	5	0.8
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	668671-668695	5	0.8
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	1507759-1507783	5	0.8
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	580563-580587	5	0.8
NC_019693_23	23.1|2811579|28|NC_019693|CRISPRCasFinder	2811579-2811606	28	NZ_CP050105	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b6, complete sequence	328448-328475	6	0.786
NC_019693_23	23.1|2811579|28|NC_019693|CRISPRCasFinder	2811579-2811606	28	NZ_CP025014	Rhizobium leguminosarum strain Norway plasmid pRLN2, complete sequence	214101-214128	6	0.786
NC_019693_23	23.1|2811579|28|NC_019693|CRISPRCasFinder	2811579-2811606	28	NZ_CP050110	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b4, complete sequence	328450-328477	6	0.786
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	473949-473973	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	935829-935853	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1144034-1144058	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1273612-1273636	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1332384-1332408	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1612122-1612146	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1366750-1366774	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1436238-1436262	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1765704-1765728	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	41342-41366	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	590802-590826	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	602728-602752	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	64021-64045	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	100692-100716	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	349073-349097	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	85980-86004	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	371970-371994	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	748404-748428	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	150338-150362	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	176431-176455	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	210218-210242	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	217326-217350	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	176493-176517	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	414108-414132	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	64562-64586	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	959959-959983	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1106229-1106253	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1859693-1859717	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	419441-419465	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	693750-693774	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	969383-969407	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1029113-1029137	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1569041-1569065	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	30880-30904	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	309600-309624	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	633179-633203	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	640419-640443	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	190740-190764	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	285490-285514	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1033645-1033669	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1171150-1171174	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	268239-268263	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1632726-1632750	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1837147-1837171	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	928799-928823	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP007796	Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence	203539-203563	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP007796	Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence	480910-480934	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP007797	Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence	285599-285623	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP007797	Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence	9264-9288	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP007797	Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence	176745-176769	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_016624	Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence	254517-254541	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	124277-124301	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	994049-994073	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	529636-529660	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	681437-681461	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032341	Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence	704268-704292	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	384433-384457	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	495699-495723	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	355517-355541	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	659050-659074	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	344958-344982	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	181079-181103	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	868070-868094	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	585185-585209	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	701782-701806	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	89434-89458	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP033315	Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence	445971-445995	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP033315	Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence	699943-699967	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	629994-630018	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	211534-211558	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	351710-351734	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	148605-148629	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	648385-648409	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	469960-469984	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	1450954-1450978	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	1602757-1602781	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	261741-261765	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	1138333-1138357	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	372685-372709	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	232502-232526	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	343769-343793	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	250152-250176	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	562255-562279	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032325	Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence	225386-225410	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032325	Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence	230429-230453	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	364608-364632	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	171023-171047	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	252205-252229	6	0.76
NC_019693_46	46.1|4756725|25|NC_019693|CRISPRCasFinder	4756725-4756749	25	NZ_CP012916	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence	344343-344367	6	0.76
NC_019693_57	57.1|5530755|28|NC_019693|CRISPRCasFinder,CRT	5530755-5530782	28	NC_022603	Carnobacterium inhibens subsp. gilichinskyi plasmid pWNCR64, complete sequence	42445-42472	6	0.786
NC_019693_57	57.1|5530755|28|NC_019693|CRISPRCasFinder,CRT	5530755-5530782	28	NC_028998	Phormidium phage MIS-PhV1B, complete genome	32903-32930	6	0.786
NC_019693_57	57.1|5530755|28|NC_019693|CRISPRCasFinder,CRT	5530755-5530782	28	KF437907	Phormidium phage MIS-PhV1A, complete genome	36695-36722	6	0.786
NC_019693_57	57.2|5530815|28|NC_019693|CRISPRCasFinder,CRT	5530815-5530842	28	NC_049466	Escherichia phage vB_EcoM_4HA13, complete genome	36035-36062	6	0.786
NC_019693_57	57.2|5530815|28|NC_019693|CRISPRCasFinder,CRT	5530815-5530842	28	MF063068	Pseudomonas phage Noxifer, complete genome	80537-80564	6	0.786
NC_019693_58	58.1|5531118|28|NC_019693|CRISPRCasFinder	5531118-5531145	28	NZ_CP025547	Mycobacterium paragordonae strain 49061 plasmid unnamed1, complete sequence	102061-102088	6	0.786
NC_019693_58	58.1|5531118|28|NC_019693|CRISPRCasFinder	5531118-5531145	28	NC_022654	Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence	115849-115876	6	0.786
NC_019693_59	59.1|5586268|34|NC_019693|CRISPRCasFinder	5586268-5586301	34	NZ_CP022220	Bradyrhizobium guangxiense strain CCBAU 53363 plasmid p53363, complete sequence	113017-113050	6	0.824
NC_019693_59	59.1|5586268|34|NC_019693|CRISPRCasFinder	5586268-5586301	34	NZ_CP030052	Bradyrhizobium guangdongense strain CCBAU 51649 plasmid unnamed, complete sequence	705051-705084	6	0.824
NC_019693_59	59.1|5586268|34|NC_019693|CRISPRCasFinder	5586268-5586301	34	NZ_CP030054	Bradyrhizobium guangzhouense strain CCBAU 51670 plasmid unnamed1, complete sequence	884645-884678	6	0.824
NC_019693_23	23.1|2811579|28|NC_019693|CRISPRCasFinder	2811579-2811606	28	NZ_CP040345	Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence	53600-53627	7	0.75
NC_019693_28	28.1|3497309|32|NC_019693|PILER-CR	3497309-3497340	32	NZ_CP038863	Campylobacter jejuni strain SCJK2 plasmid unnamed1, complete sequence	14913-14944	7	0.781
NC_019693_28	28.1|3497309|32|NC_019693|PILER-CR	3497309-3497340	32	MT777452	Bacillus phage Baseball_field, complete genome	1551-1582	7	0.781
NC_019693_38	38.1|4355493|30|NC_019693|CRISPRCasFinder	4355493-4355522	30	NZ_CP053930	Bacillus cereus strain FDAARGOS_797 plasmid unnamed1, complete sequence	188826-188855	7	0.767
NC_019693_38	38.1|4355493|30|NC_019693|CRISPRCasFinder	4355493-4355522	30	NZ_CP040341	Bacillus cereus strain DLOU-Tangshan plasmid unnamed1, complete sequence	200203-200232	7	0.767
NC_019693_38	38.1|4355493|30|NC_019693|CRISPRCasFinder	4355493-4355522	30	NZ_CP053290	Bacillus cereus strain WPySW2 plasmid unnamed, complete sequence	235235-235264	7	0.767
NC_019693_38	38.1|4355493|30|NC_019693|CRISPRCasFinder	4355493-4355522	30	NZ_CP042928	Bacillus cereus strain G1-1 plasmid unnamed, complete sequence	103047-103076	7	0.767
NC_019693_38	38.1|4355493|30|NC_019693|CRISPRCasFinder	4355493-4355522	30	NZ_CP009299	Bacillus cereus D17 plasmid unnamed, complete sequence	199248-199277	7	0.767
NC_019693_38	38.1|4355493|30|NC_019693|CRISPRCasFinder	4355493-4355522	30	NZ_CP045273	Bacillus megaterium strain FDU301 plasmid pFDU301A, complete sequence	201750-201779	7	0.767
NC_019693_38	38.1|4355493|30|NC_019693|CRISPRCasFinder	4355493-4355522	30	NZ_CP013691	Myroides odoratimimus strain PR63039 plasmid p63039, complete sequence	31317-31346	7	0.767
NC_019693_38	38.1|4355493|30|NC_019693|CRISPRCasFinder	4355493-4355522	30	MK893987	Staphylococcus phage PMBT8, complete genome	16905-16934	7	0.767
NC_019693_67	67.18|6252771|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT	6252771-6252807	37	NZ_CP018750	Borreliella garinii strain CIP 103362 isolate 20047 plasmid cp26, complete sequence	5494-5530	7	0.811
NC_019693_67	67.18|6252771|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT	6252771-6252807	37	NZ_CP028867	Borreliella garinii strain 20047 plasmid cp26, complete sequence	20279-20315	7	0.811
NC_019693_67	67.18|6252771|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT	6252771-6252807	37	NC_017725	Borreliella garinii BgVir plasmid cp26, complete sequence	1793-1829	7	0.811
NC_019693_67	67.18|6252771|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT	6252771-6252807	37	NC_006128	Borreliella bavariensis PBi plasmid cp26, complete sequence	1801-1837	7	0.811
NC_019693_82	82.1|7581848|30|NC_019693|CRISPRCasFinder	7581848-7581877	30	NC_019700	Oscillatoria acuminata PCC 6304 plasmid pOSCIL6304.01, complete sequence	9930-9959	7	0.767
NC_019693_28	28.3|3497307|34|NC_019693|CRISPRCasFinder	3497307-3497340	34	NZ_CP038863	Campylobacter jejuni strain SCJK2 plasmid unnamed1, complete sequence	14912-14945	8	0.765
NC_019693_38	38.1|4355493|30|NC_019693|CRISPRCasFinder	4355493-4355522	30	KX119175	Helicobacter phage Pt22899G, complete genome	514-543	8	0.733
NC_019693_39	39.10|4395684|31|NC_019693|PILER-CR,CRISPRCasFinder,CRT	4395684-4395714	31	NZ_CP018468	Xanthomonas vesicatoria strain LM159 plasmid pLM159.1, complete sequence	198100-198130	8	0.742
NC_019693_39	39.20|4396403|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT	4396403-4396437	35	NC_021856	Bacillus phage phiNIT1 DNA, complete genome	32094-32128	8	0.771
NC_019693_39	39.20|4396403|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT	4396403-4396437	35	MF422185	Bacillus phage BSP10, complete genome	110760-110794	8	0.771
NC_019693_39	39.20|4396403|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT	4396403-4396437	35	NC_022771	Bacillus phage Grass, complete genome	29901-29935	8	0.771
NC_019693_39	39.20|4396403|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT	4396403-4396437	35	MG000860	Bacillus phage BSP9, complete genome	111419-111453	8	0.771
NC_019693_57	57.1|5530755|28|NC_019693|CRISPRCasFinder,CRT	5530755-5530782	28	CP040041	Acinetobacter baumannii strain VB958 plasmid unnamed1, complete sequence	218332-218359	8	0.714
NC_019693_66	66.3|6235077|35|NC_019693|CRISPRCasFinder,PILER-CR	6235077-6235111	35	MN694423	Marine virus AFVG_250M1001, complete genome	4863-4897	8	0.771
NC_019693_67	67.11|6252258|32|NC_019693|PILER-CR,CRISPRCasFinder,CRT	6252258-6252289	32	NZ_CP049245	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed4, complete sequence	150107-150138	8	0.75
NC_019693_67	67.11|6252258|32|NC_019693|PILER-CR,CRISPRCasFinder,CRT	6252258-6252289	32	NZ_LR723671	Rhizobium flavum strain YW14 plasmid 2	142225-142256	8	0.75
NC_019693_67	67.11|6252258|32|NC_019693|PILER-CR,CRISPRCasFinder,CRT	6252258-6252289	32	NZ_CP030264	Ensifer adhaerens strain Corn53 plasmid AB, complete sequence	942914-942945	8	0.75
NC_019693_67	67.11|6252258|32|NC_019693|PILER-CR,CRISPRCasFinder,CRT	6252258-6252289	32	MF472895	Mycobacterium phage Kimona, complete genome	4615-4646	8	0.75
NC_019693_75	75.22|7040498|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7040498-7040531	34	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	718416-718449	8	0.765
NC_019693_80	80.55|7508201|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7508201-7508234	34	KY554775	Lactococcus phage AM11, complete genome	97601-97634	8	0.765
NC_019693_80	80.55|7508201|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7508201-7508234	34	KY554773	Lactococcus phage AM8, complete genome	97616-97649	8	0.765
NC_019693_80	80.55|7508201|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7508201-7508234	34	KY554768	Lactococcus phage AM1, complete genome	97097-97130	8	0.765
NC_019693_80	80.55|7508201|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7508201-7508234	34	KY554769	Lactococcus phage AM2, complete genome	97094-97127	8	0.765
NC_019693_80	80.55|7508201|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7508201-7508234	34	KY554770	Lactococcus phage AM3, complete genome	97471-97504	8	0.765
NC_019693_80	80.55|7508201|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7508201-7508234	34	KY554776	Lactococcus phage AM12, complete genome	96851-96884	8	0.765
NC_019693_80	80.55|7508201|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7508201-7508234	34	KY554774	Lactococcus phage AM9, complete genome	96868-96901	8	0.765
NC_019693_80	80.67|7509065|33|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7509065-7509097	33	NZ_CP049906	Diaphorobacter sp. HDW4B plasmid unnamed1, complete sequence	411306-411338	8	0.758
NC_019693_39	39.10|4395684|31|NC_019693|PILER-CR,CRISPRCasFinder,CRT	4395684-4395714	31	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1692528-1692558	9	0.71
NC_019693_39	39.25|4396770|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	4396770-4396803	34	NC_012854	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132505, complete sequence	15845-15878	9	0.735
NC_019693_80	80.30|7506404|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7506404-7506437	34	NZ_CP014277	Martelella sp. AD-3 plasmid unnamed2, complete sequence	105380-105413	9	0.735
NC_019693_80	80.30|7506404|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7506404-7506437	34	NZ_CP020332	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM259, complete sequence	193184-193217	9	0.735
NC_019693_80	80.63|7508781|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7508781-7508814	34	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	21176-21209	9	0.735
NC_019693_80	80.63|7508781|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7508781-7508814	34	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	791940-791973	9	0.735
NC_019693_39	39.1|4395032|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT	4395032-4395067	36	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1503080-1503115	10	0.722
NC_019693_39	39.16|4396115|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT	4396115-4396150	36	MK017820	Clostridium phage CPD7, complete genome	14735-14770	10	0.722
NC_019693_39	39.50|4398607|34|NC_019693|CRISPRCasFinder,CRT,PILER-CR	4398607-4398640	34	NZ_CP049319	Caballeronia sp. SBC2 plasmid pSBC2-3, complete sequence	303367-303400	10	0.706
NC_019693_39	39.50|4398607|34|NC_019693|CRISPRCasFinder,CRT,PILER-CR	4398607-4398640	34	NZ_CP049159	Caballeronia sp. SBC1 plasmid pSBC1_3, complete sequence	137644-137677	10	0.706
NC_019693_75	75.47|7042324|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7042324-7042357	34	NZ_CP049816	Monaibacterium sp. ALG8 plasmid unnamed5, complete sequence	13068-13101	10	0.706
NC_019693_75	75.50|7042549|35|NC_019693|CRISPRCasFinder,CRT,PILER-CR	7042549-7042583	35	NZ_CP026517	Deinococcus sp. NW-56 plasmid unnamed1, complete sequence	267130-267164	11	0.686
NC_019693_75	75.50|7042549|35|NC_019693|CRISPRCasFinder,CRT,PILER-CR	7042549-7042583	35	NZ_CP026518	Deinococcus sp. NW-56 plasmid unnamed2, complete sequence	90943-90977	11	0.686
NC_019693_75	75.50|7042549|35|NC_019693|CRISPRCasFinder,CRT,PILER-CR	7042549-7042583	35	NZ_CP026518	Deinococcus sp. NW-56 plasmid unnamed2, complete sequence	358675-358709	11	0.686
NC_019693_80	80.5|7504592|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7504592-7504625	34	NZ_CP046707	Nostoc sp. ATCC 53789 plasmid pNsp_d, complete sequence	46802-46835	12	0.647
NC_019693_80	80.5|7504592|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7504592-7504625	34	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	611395-611428	12	0.647
NC_019693_80	80.5|7504592|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT	7504592-7504625	34	NZ_CP026690	Nostoc sp. 'Peltigera membranacea cyanobiont' N6 plasmid pNPM8, complete sequence	15594-15627	12	0.647

1. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 2, identity: 0.92

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccctaaccctccccttgt	Protospacer
 *********************** 

2. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP043057 (Dolichospermum sp. UHCC 0315A plasmid pUHCC0315a, complete sequence) position: , mismatch: 2, identity: 0.92

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccctaaccctccccttgt	Protospacer
 *********************** 

3. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP043059 (Dolichospermum sp. UHCC 0315A plasmid pUHCC0315c, complete sequence) position: , mismatch: 2, identity: 0.92

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccctaaccctccccttgt	Protospacer
 *********************** 

4. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_AP017564 (Pseudanabaena sp. ABRG5-3 plasmid ABRG53d, complete sequence) position: , mismatch: 2, identity: 0.92

aaccccaccctaaccctccccttgg	CRISPR spacer
aacccctccctaaccctccccttgc	Protospacer
****** ***************** 

5. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_AP017564 (Pseudanabaena sp. ABRG5-3 plasmid ABRG53d, complete sequence) position: , mismatch: 2, identity: 0.92

aaccccaccctaaccctccccttgg	CRISPR spacer
aacccctccctaaccctccccttgc	Protospacer
****** ***************** 

6. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_AP017564 (Pseudanabaena sp. ABRG5-3 plasmid ABRG53d, complete sequence) position: , mismatch: 2, identity: 0.92

aaccccaccctaaccctccccttgg	CRISPR spacer
aacccctccctaaccctccccttgc	Protospacer
****** ***************** 

7. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_AP017383 (Moraxella osloensis strain KMC41 plasmid pMOSL2, complete sequence) position: , mismatch: 2, identity: 0.92

aaccccaccctaaccctccccttgg	CRISPR spacer
aaccccaccccaaccctccccttag	Protospacer
**********.************.*

8. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP024183 (Moraxella osloensis strain KSH plasmid p3, complete sequence) position: , mismatch: 2, identity: 0.92

aaccccaccctaaccctccccttgg	CRISPR spacer
aaccccaccccaaccctccccttag	Protospacer
**********.************.*

9. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP024447 (Moraxella osloensis strain NP7 plasmid pNP7-4, complete sequence) position: , mismatch: 2, identity: 0.92

aaccccaccctaaccctccccttgg	CRISPR spacer
aaccccaccccaaccctccccttag	Protospacer
**********.************.*

10. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP024792 (Nostoc flagelliforme CCNUN1 plasmid pNFSY07, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccctaaccctccccttat	Protospacer
 **********************. 

11. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054609 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
caccccacccaaaccctccccttgt	Protospacer
 ********* ************* 

12. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
aaccccacccaaaccctccccttcc	Protospacer
********** ************  

13. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
tacccctccctaaccctccccttgt	Protospacer
 ***** ***************** 

14. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP036488 (Rahnella aquatilis strain MEM40 plasmid pMEM40-1, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

15. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP036488 (Rahnella aquatilis strain MEM40 plasmid pMEM40-1, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

16. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP036488 (Rahnella aquatilis strain MEM40 plasmid pMEM40-1, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

17. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032297 (Rahnella aquatilis strain ZF7 plasmid pRAZF7, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

18. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032297 (Rahnella aquatilis strain ZF7 plasmid pRAZF7, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

19. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032297 (Rahnella aquatilis strain ZF7 plasmid pRAZF7, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

20. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_017060 (Rahnella aquatilis HX2 plasmid PRA1, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

21. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_017060 (Rahnella aquatilis HX2 plasmid PRA1, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

22. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_017060 (Rahnella aquatilis HX2 plasmid PRA1, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

23. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_017588 (Thermus thermophilus JL-18 plasmid pTTJL1801, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
gaccccacccttcccctccccttgg	Protospacer
.**********  ************

24. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP034838 (Rahnella aquatilis strain KM12 plasmid pKM12v1, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

25. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP034838 (Rahnella aquatilis strain KM12 plasmid pKM12v1, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

26. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP034838 (Rahnella aquatilis strain KM12 plasmid pKM12v1, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

27. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP034838 (Rahnella aquatilis strain KM12 plasmid pKM12v1, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

28. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP034839 (Rahnella aquatilis strain KM25 plasmid pKM12v2, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

29. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP034839 (Rahnella aquatilis strain KM25 plasmid pKM12v2, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

30. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP034839 (Rahnella aquatilis strain KM25 plasmid pKM12v2, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

31. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP034839 (Rahnella aquatilis strain KM25 plasmid pKM12v2, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

32. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP034837 (Rahnella aquatilis strain KM05 plasmid pKM05, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

33. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP034837 (Rahnella aquatilis strain KM05 plasmid pKM05, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

34. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP034837 (Rahnella aquatilis strain KM05 plasmid pKM05, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

35. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_015062 (Rahnella sp. Y9602 plasmid pRAHAQ01, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
taccccaccccaaccctccccttcg	Protospacer
 *********.************ *

36. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_015062 (Rahnella sp. Y9602 plasmid pRAHAQ01, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
acccccaccccaaccctccccttcg	Protospacer
* ********.************ *

37. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP024186 (Moraxella osloensis strain TT16 plasmid p1, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
aaccccaacccaaccctccccttag	Protospacer
******* **.************.*

38. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP024177 (Moraxella osloensis strain YHS plasmid pYHS1, complete sequence) position: , mismatch: 3, identity: 0.88

aaccccaccctaaccctccccttgg	CRISPR spacer
aaccccaacccaaccctccccttag	Protospacer
******* **.************.*

39. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 4, identity: 0.84

aaccccaccctaaccctccccttgg	CRISPR spacer
caccccacccaaaccctcccctgag	Protospacer
 ********* *********** .*

40. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 4, identity: 0.84

aaccccaccctaaccctccccttgg	CRISPR spacer
caccccacccaaaccctcccctcgt	Protospacer
 ********* ***********.* 

41. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 4, identity: 0.84

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccctgcg	Protospacer
. ********************  *

42. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_008608 (Pelobacter propionicus DSM 2379 plasmid pPRO2, complete sequence) position: , mismatch: 4, identity: 0.84

aaccccaccctaaccctccccttgg	CRISPR spacer
gacccctccctaaccctcccctcag	Protospacer
.***** ***************..*

43. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP033227 (Sphingobium yanoikuyae strain SJTF8 plasmid pF1, complete sequence) position: , mismatch: 4, identity: 0.84

aaccccaccctaaccctccccttgg	CRISPR spacer
acccccaccctaaccctccccctaa	Protospacer
* *******************.*..

44. spacer 56.1|5530383|25|NC_019693|CRISPRCasFinder matches to MK490927 (Phage Altai3, complete genome) position: , mismatch: 4, identity: 0.84

ggatgaggagatgtcctggaatgag	CRISPR spacer
ggatgatgtgatgtcctggaatggt	Protospacer
****** * **************. 

45. spacer 4.1|222750|30|NC_019693|CRISPRCasFinder matches to NZ_AP017564 (Pseudanabaena sp. ABRG5-3 plasmid ABRG53d, complete sequence) position: , mismatch: 5, identity: 0.833

cggtcccctccccttagcaaggggagggtt	CRISPR spacer
taattccctcccctttgcaaggggagggtt	Protospacer
...*.********** **************

46. spacer 33.1|3787169|27|NC_019693|CRISPRCasFinder matches to NC_014827 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL04, complete sequence) position: , mismatch: 5, identity: 0.815

ggagaatcaaagccccttataccgttc	CRISPR spacer
tgataatctaagccccttataccgtag	Protospacer
 ** **** ****************  

47. spacer 33.1|3787169|27|NC_019693|CRISPRCasFinder matches to NC_014827 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL04, complete sequence) position: , mismatch: 5, identity: 0.815

ggagaatcaaagccccttataccgttc	CRISPR spacer
tgataatctaagccccttataccgtag	Protospacer
 ** **** ****************  

48. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
caccccacccaaaccctcccctcct	Protospacer
 ********* ***********.  

49. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
caccccacccaaaccctcccctcct	Protospacer
 ********* ***********.  

50. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
acccccaccctaaccctcccccgct	Protospacer
* *******************.   

51. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgcg	Protospacer
. *******************.  *

52. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgcg	Protospacer
. *******************.  *

53. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
acccccaccctaaccctcccccgct	Protospacer
* *******************.   

54. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
acccccaccctaaccctcccccgct	Protospacer
* *******************.   

55. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022369 (Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctccccccgc	Protospacer
. *******************..* 

56. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctccccccgc	Protospacer
. *******************..* 

57. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
acccccaccctaaccctcccccgcc	Protospacer
* *******************.   

58. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
acccccaccctaaccctcccccgct	Protospacer
* *******************.   

59. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
acccccaccctaaccctcccccgct	Protospacer
* *******************.   

60. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
acccccaccctaaccctcccccgct	Protospacer
* *******************.   

61. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
acccccaccctaaccctcccccgcc	Protospacer
* *******************.   

62. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
acccccaccctaaccctcccccgct	Protospacer
* *******************.   

63. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctccccccgc	Protospacer
. *******************..* 

64. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 5, identity: 0.8

aaccccaccctaaccctccccttgg	CRISPR spacer
acccccaccctaaccctcccccgct	Protospacer
* *******************.   

65. spacer 23.1|2811579|28|NC_019693|CRISPRCasFinder matches to NZ_CP050105 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b6, complete sequence) position: , mismatch: 6, identity: 0.786

tgagggaattttttaaaattccaggcgg	CRISPR spacer
cctgggcatttcttaaaattccaggcgt	Protospacer
.  *** ****.*************** 

66. spacer 23.1|2811579|28|NC_019693|CRISPRCasFinder matches to NZ_CP025014 (Rhizobium leguminosarum strain Norway plasmid pRLN2, complete sequence) position: , mismatch: 6, identity: 0.786

tgagggaattttttaaaattccaggcgg	CRISPR spacer
cctgggtatttcttaaaattccaggcgt	Protospacer
.  *** ****.*************** 

67. spacer 23.1|2811579|28|NC_019693|CRISPRCasFinder matches to NZ_CP050110 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b4, complete sequence) position: , mismatch: 6, identity: 0.786

tgagggaattttttaaaattccaggcgg	CRISPR spacer
cctgggcatttcttaaaattccaggcgt	Protospacer
.  *** ****.*************** 

68. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

69. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

70. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

71. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

72. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

73. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

74. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

75. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

76. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

77. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

78. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

79. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

80. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

81. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

82. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

83. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

84. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

85. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

86. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

87. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

88. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

89. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

90. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

91. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

92. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

93. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

94. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgcc	Protospacer
. *******************.   

95. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

96. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

97. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

98. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

99. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

100. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

101. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccacc	Protospacer
. *******************.   

102. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

103. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

104. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

105. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

106. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

107. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

108. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

109. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

110. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

111. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

112. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

113. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP007796 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

114. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP007796 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

115. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP007797 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

116. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP007797 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

117. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP007797 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

118. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_016624 (Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

119. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

120. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

121. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

122. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

123. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032341 (Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

124. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
ccccccaccctaaccctcccccgct	Protospacer
  *******************.   

125. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

126. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

127. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

128. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

129. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

130. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

131. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

132. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

133. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgcc	Protospacer
. *******************.   

134. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP033315 (Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgcc	Protospacer
. *******************.   

135. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP033315 (Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

136. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

137. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

138. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

139. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

140. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

141. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

142. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

143. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

144. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

145. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

146. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

147. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

148. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
ccccccaccctaaccctcccccgct	Protospacer
  *******************.   

149. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

150. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

151. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032325 (Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

152. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032325 (Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

153. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

154. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

155. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgcc	Protospacer
. *******************.   

156. spacer 46.1|4756725|25|NC_019693|CRISPRCasFinder matches to NZ_CP012916 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence) position: , mismatch: 6, identity: 0.76

aaccccaccctaaccctccccttgg	CRISPR spacer
gcccccaccctaaccctcccccgct	Protospacer
. *******************.   

157. spacer 57.1|5530755|28|NC_019693|CRISPRCasFinder,CRT matches to NC_022603 (Carnobacterium inhibens subsp. gilichinskyi plasmid pWNCR64, complete sequence) position: , mismatch: 6, identity: 0.786

ctcggaacctgagaaatttttagaagaa	CRISPR spacer
ttatgatcctgagaaatatttagaagag	Protospacer
.*  ** ********** *********.

158. spacer 57.1|5530755|28|NC_019693|CRISPRCasFinder,CRT matches to NC_028998 (Phormidium phage MIS-PhV1B, complete genome) position: , mismatch: 6, identity: 0.786

ctcggaacctgagaaatttttagaagaa	CRISPR spacer
accagaacctgagaaattattagaacca	Protospacer
 .*.************** ******  *

159. spacer 57.1|5530755|28|NC_019693|CRISPRCasFinder,CRT matches to KF437907 (Phormidium phage MIS-PhV1A, complete genome) position: , mismatch: 6, identity: 0.786

ctcggaacctgagaaatttttagaagaa	CRISPR spacer
accagaacctgagaaattattagaacca	Protospacer
 .*.************** ******  *

160. spacer 57.2|5530815|28|NC_019693|CRISPRCasFinder,CRT matches to NC_049466 (Escherichia phage vB_EcoM_4HA13, complete genome) position: , mismatch: 6, identity: 0.786

caatgatagtgaagtcaccgtcgaacag	CRISPR spacer
caatgatagtgaagtcaccatctttgat	Protospacer
*******************.**    * 

161. spacer 57.2|5530815|28|NC_019693|CRISPRCasFinder,CRT matches to MF063068 (Pseudomonas phage Noxifer, complete genome) position: , mismatch: 6, identity: 0.786

caatgatagtgaagtcaccgtcgaacag	CRISPR spacer
caatgatcgtgaagtcaacgtcgtgctc	Protospacer
******* ********* ***** .*  

162. spacer 58.1|5531118|28|NC_019693|CRISPRCasFinder matches to NZ_CP025547 (Mycobacterium paragordonae strain 49061 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

ctccgaacccgaactgttctgggatagt	CRISPR spacer
atccgagcccgaactgctctgggacaac	Protospacer
 *****.*********.*******.*..

163. spacer 58.1|5531118|28|NC_019693|CRISPRCasFinder matches to NC_022654 (Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence) position: , mismatch: 6, identity: 0.786

ctccgaacccgaactgttctgggatagt	CRISPR spacer
atccgagcccgaactgctctgggacaac	Protospacer
 *****.*********.*******.*..

164. spacer 59.1|5586268|34|NC_019693|CRISPRCasFinder matches to NZ_CP022220 (Bradyrhizobium guangxiense strain CCBAU 53363 plasmid p53363, complete sequence) position: , mismatch: 6, identity: 0.824

attaccaattgaatgacgaaaaat-cgtgatttcg	CRISPR spacer
attaccaattgaatgtcgagaaatacgtgccttt-	Protospacer
*************** ***.**** **** .**. 

165. spacer 59.1|5586268|34|NC_019693|CRISPRCasFinder matches to NZ_CP030052 (Bradyrhizobium guangdongense strain CCBAU 51649 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.824

attaccaattgaatgacgaaaaat-cgtgatttcg	CRISPR spacer
attaccaattgaatgtcgagaaatacgtgccttt-	Protospacer
*************** ***.**** **** .**. 

166. spacer 59.1|5586268|34|NC_019693|CRISPRCasFinder matches to NZ_CP030054 (Bradyrhizobium guangzhouense strain CCBAU 51670 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.824

attaccaattgaatgacgaaaaat-cgtgatttcg	CRISPR spacer
attaccaattgaatgtcgagaaatacgtgccttt-	Protospacer
*************** ***.**** **** .**. 

167. spacer 23.1|2811579|28|NC_019693|CRISPRCasFinder matches to NZ_CP040345 (Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.75

tgagggaattttttaaaattccaggcgg	CRISPR spacer
agaaggaattttttaaaattcctatcct	Protospacer
 **.****************** . *  

168. spacer 28.1|3497309|32|NC_019693|PILER-CR matches to NZ_CP038863 (Campylobacter jejuni strain SCJK2 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tgattcagaacgatattatattgattttgctg	CRISPR spacer
taaacgagaaggaaattatattgattttgctt	Protospacer
*.* . **** ** ***************** 

169. spacer 28.1|3497309|32|NC_019693|PILER-CR matches to MT777452 (Bacillus phage Baseball_field, complete genome) position: , mismatch: 7, identity: 0.781

tgattcagaacgatattatattgattttgctg	CRISPR spacer
tgaaggagaaagatattatattggttttgaag	Protospacer
***   **** ************.*****  *

170. spacer 38.1|4355493|30|NC_019693|CRISPRCasFinder matches to NZ_CP053930 (Bacillus cereus strain FDAARGOS_797 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

tttttattctcttttgaaaagagacctaac	CRISPR spacer
tttttatcctcttttgaaaagatactgttt	Protospacer
*******.************** **.   .

171. spacer 38.1|4355493|30|NC_019693|CRISPRCasFinder matches to NZ_CP040341 (Bacillus cereus strain DLOU-Tangshan plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

tttttattctcttttgaaaagagacctaac	CRISPR spacer
tttttatcctcttttgaaaagatactgttt	Protospacer
*******.************** **.   .

172. spacer 38.1|4355493|30|NC_019693|CRISPRCasFinder matches to NZ_CP053290 (Bacillus cereus strain WPySW2 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

tttttattctcttttgaaaagagacctaac	CRISPR spacer
tttttatcctcttttgaaaagatactgttt	Protospacer
*******.************** **.   .

173. spacer 38.1|4355493|30|NC_019693|CRISPRCasFinder matches to NZ_CP042928 (Bacillus cereus strain G1-1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

tttttattctcttttgaaaagagacctaac	CRISPR spacer
tttttatcctcttttgaaaagatactgttt	Protospacer
*******.************** **.   .

174. spacer 38.1|4355493|30|NC_019693|CRISPRCasFinder matches to NZ_CP009299 (Bacillus cereus D17 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

tttttattctcttttgaaaagagacctaac	CRISPR spacer
tttttatcctcttttgaaaagatactgttt	Protospacer
*******.************** **.   .

175. spacer 38.1|4355493|30|NC_019693|CRISPRCasFinder matches to NZ_CP045273 (Bacillus megaterium strain FDU301 plasmid pFDU301A, complete sequence) position: , mismatch: 7, identity: 0.767

tttttattctcttttgaaaagagacctaac	CRISPR spacer
tttttattctcttttgcaaagtaattagac	Protospacer
**************** **** .*.. .**

176. spacer 38.1|4355493|30|NC_019693|CRISPRCasFinder matches to NZ_CP013691 (Myroides odoratimimus strain PR63039 plasmid p63039, complete sequence) position: , mismatch: 7, identity: 0.767

tttttattctcttttgaaaagagacctaac	CRISPR spacer
tttttgttctcttttgaaaagaaaaaaata	Protospacer
*****.****************.*   *  

177. spacer 38.1|4355493|30|NC_019693|CRISPRCasFinder matches to MK893987 (Staphylococcus phage PMBT8, complete genome) position: , mismatch: 7, identity: 0.767

tttttattctcttttgaaaagagacctaac	CRISPR spacer
tttttattctcttttggaaagcctcttctc	Protospacer
****************.****   *.*  *

178. spacer 67.18|6252771|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018750 (Borreliella garinii strain CIP 103362 isolate 20047 plasmid cp26, complete sequence) position: , mismatch: 7, identity: 0.811

aaaatagaaaaataacgaaaagcccaattttcaatat	CRISPR spacer
aaatcaaattaataacgagaagccctattttcaatat	Protospacer
*** .*.*  ********.****** ***********

179. spacer 67.18|6252771|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028867 (Borreliella garinii strain 20047 plasmid cp26, complete sequence) position: , mismatch: 7, identity: 0.811

aaaatagaaaaataacgaaaagcccaattttcaatat	CRISPR spacer
aaatcaaattaataacgagaagccctattttcaatat	Protospacer
*** .*.*  ********.****** ***********

180. spacer 67.18|6252771|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NC_017725 (Borreliella garinii BgVir plasmid cp26, complete sequence) position: , mismatch: 7, identity: 0.811

aaaatagaaaaataacgaaaagcccaattttcaatat	CRISPR spacer
aaatcaaattaataacgagaagccctattttcaatat	Protospacer
*** .*.*  ********.****** ***********

181. spacer 67.18|6252771|37|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NC_006128 (Borreliella bavariensis PBi plasmid cp26, complete sequence) position: , mismatch: 7, identity: 0.811

aaaatagaaaaataacgaaaagcccaattttcaatat	CRISPR spacer
aaatcaaattaataacgagaagccctattttcaatat	Protospacer
*** .*.*  ********.****** ***********

182. spacer 82.1|7581848|30|NC_019693|CRISPRCasFinder matches to NC_019700 (Oscillatoria acuminata PCC 6304 plasmid pOSCIL6304.01, complete sequence) position: , mismatch: 7, identity: 0.767

tatcgggctactccggtcccctccccttag	CRISPR spacer
ggaggggcttctccggtcccctcccctggg	Protospacer
 .  ***** ***************** .*

183. spacer 28.3|3497307|34|NC_019693|CRISPRCasFinder matches to NZ_CP038863 (Campylobacter jejuni strain SCJK2 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

atgattcagaacgatattatattgattttgctga	CRISPR spacer
ataaacgagaaggaaattatattgattttgcttt	Protospacer
**.* . **** ** *****************  

184. spacer 38.1|4355493|30|NC_019693|CRISPRCasFinder matches to KX119175 (Helicobacter phage Pt22899G, complete genome) position: , mismatch: 8, identity: 0.733

tttttattctcttttgaaaagagacctaac	CRISPR spacer
tttgtattctcgtttgaaaagagtaaaagt	Protospacer
*** ******* ***********    *..

185. spacer 39.10|4395684|31|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018468 (Xanthomonas vesicatoria strain LM159 plasmid pLM159.1, complete sequence) position: , mismatch: 8, identity: 0.742

gaataagatcggcaatctcgtttgtacccat	CRISPR spacer
tccttggctcggcaatctcgctggtacccat	Protospacer
   * .* ************.* ********

186. spacer 39.20|4396403|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NC_021856 (Bacillus phage phiNIT1 DNA, complete genome) position: , mismatch: 8, identity: 0.771

ttaagctgt---gcggtccagagctccggatagctctt	CRISPR spacer
---aattgtaaaacggtccaaagctcctgatagctctt	Protospacer
   *..***   .*******.****** **********

187. spacer 39.20|4396403|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to MF422185 (Bacillus phage BSP10, complete genome) position: , mismatch: 8, identity: 0.771

ttaagctgt---gcggtccagagctccggatagctctt	CRISPR spacer
---aattgtaaaacggtccaaagctcctgatagctctt	Protospacer
   *..***   .*******.****** **********

188. spacer 39.20|4396403|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NC_022771 (Bacillus phage Grass, complete genome) position: , mismatch: 8, identity: 0.771

ttaagctgt---gcggtccagagctccggatagctctt	CRISPR spacer
---aattgtaaaacggtccaaagctcctgatagctctt	Protospacer
   *..***   .*******.****** **********

189. spacer 39.20|4396403|35|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to MG000860 (Bacillus phage BSP9, complete genome) position: , mismatch: 8, identity: 0.771

ttaagctgt---gcggtccagagctccggatagctctt	CRISPR spacer
---aattgtaaaacggtccaaagctcctgatagctctt	Protospacer
   *..***   .*******.****** **********

190. spacer 57.1|5530755|28|NC_019693|CRISPRCasFinder,CRT matches to CP040041 (Acinetobacter baumannii strain VB958 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.714

ctcggaacctgagaaatttttagaagaa	CRISPR spacer
tgatgaacctgagaaaattttagaattg	Protospacer
.   ************ ********  .

191. spacer 66.3|6235077|35|NC_019693|CRISPRCasFinder,PILER-CR matches to MN694423 (Marine virus AFVG_250M1001, complete genome) position: , mismatch: 8, identity: 0.771

tcatacaaagcatcacttatgtattgttctgaaaa	CRISPR spacer
tcgtcaaatgcttcacttatgtattgttctgcatc	Protospacer
**.*  ** ** ******************* *  

192. spacer 67.11|6252258|32|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049245 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.75

ctcgactgggccgcgcagctttatgggttcac	CRISPR spacer
ttcgactggaccgcgcagctttaagggcaggg	Protospacer
.********.************* ***.  . 

193. spacer 67.11|6252258|32|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR723671 (Rhizobium flavum strain YW14 plasmid 2) position: , mismatch: 8, identity: 0.75

ctcgactgggccgcgcagctttatgggttcac	CRISPR spacer
ttcgactggaccgcgcagctttaagggcaggg	Protospacer
.********.************* ***.  . 

194. spacer 67.11|6252258|32|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030264 (Ensifer adhaerens strain Corn53 plasmid AB, complete sequence) position: , mismatch: 8, identity: 0.75

ctcgactgggccgcgcagctttatgggttcac	CRISPR spacer
ttcgactggaccgcgcagctttaagggcaggg	Protospacer
.********.************* ***.  . 

195. spacer 67.11|6252258|32|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to MF472895 (Mycobacterium phage Kimona, complete genome) position: , mismatch: 8, identity: 0.75

ctcgactgggccgcgcagctttatgggttcac	CRISPR spacer
ctcgactgggccgcacagctctacgagcgcga	Protospacer
**************.*****.**.*.*. *. 

196. spacer 75.22|7040498|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

caccagacgcacggacccatcggcccagacatcg	CRISPR spacer
ccacagacgcacggccccatcggccgagccgacc	Protospacer
*  *********** ********** ** *. * 

197. spacer 80.55|7508201|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to KY554775 (Lactococcus phage AM11, complete genome) position: , mismatch: 8, identity: 0.765

ataggtctactgcgttttgccataaagt-ccacaa	CRISPR spacer
atttgtctactgcgtttttccataaggtatcatc-	Protospacer
**  ************** ******.** .**.  

198. spacer 80.55|7508201|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to KY554773 (Lactococcus phage AM8, complete genome) position: , mismatch: 8, identity: 0.765

ataggtctactgcgttttgccataaagt-ccacaa	CRISPR spacer
atttgtctactgcgtttttccataaggtatcatc-	Protospacer
**  ************** ******.** .**.  

199. spacer 80.55|7508201|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to KY554768 (Lactococcus phage AM1, complete genome) position: , mismatch: 8, identity: 0.765

ataggtctactgcgttttgccataaagt-ccacaa	CRISPR spacer
atttgtctactgcgtttttccataaggtatcatc-	Protospacer
**  ************** ******.** .**.  

200. spacer 80.55|7508201|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to KY554769 (Lactococcus phage AM2, complete genome) position: , mismatch: 8, identity: 0.765

ataggtctactgcgttttgccataaagt-ccacaa	CRISPR spacer
atttgtctactgcgtttttccataaggtatcatc-	Protospacer
**  ************** ******.** .**.  

201. spacer 80.55|7508201|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to KY554770 (Lactococcus phage AM3, complete genome) position: , mismatch: 8, identity: 0.765

ataggtctactgcgttttgccataaagt-ccacaa	CRISPR spacer
atttgtctactgcgtttttccataaggtatcatc-	Protospacer
**  ************** ******.** .**.  

202. spacer 80.55|7508201|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to KY554776 (Lactococcus phage AM12, complete genome) position: , mismatch: 8, identity: 0.765

ataggtctactgcgttttgccataaagt-ccacaa	CRISPR spacer
atttgtctactgcgtttttccataaggtatcatc-	Protospacer
**  ************** ******.** .**.  

203. spacer 80.55|7508201|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to KY554774 (Lactococcus phage AM9, complete genome) position: , mismatch: 8, identity: 0.765

ataggtctactgcgttttgccataaagt-ccacaa	CRISPR spacer
atttgtctactgcgtttttccataaggtatcatc-	Protospacer
**  ************** ******.** .**.  

204. spacer 80.67|7509065|33|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049906 (Diaphorobacter sp. HDW4B plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

ccaggaatggaaagcagggattctccggcaatg	CRISPR spacer
acttcaacggaaagcagggattcgccggcaagc	Protospacer
 *   **.*************** *******  

205. spacer 39.10|4395684|31|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 9, identity: 0.71

gaataagatcggcaatctcgtttgtacccat	CRISPR spacer
atcacggattggcaatctcgtttgtagccag	Protospacer
.    .***.**************** *** 

206. spacer 39.25|4396770|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NC_012854 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132505, complete sequence) position: , mismatch: 9, identity: 0.735

ggaaatctttgctgaaagccgtgaggtaagaccg	CRISPR spacer
ggaaatcattgctgaaatccgtgacctcggattc	Protospacer
******* ********* ******  * .**.. 

207. spacer 80.30|7506404|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014277 (Martelella sp. AD-3 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.735

ccagtt--ttttctctccagcttcccgcgccttatg	CRISPR spacer
--gattaactttctctccagcttccccggccttttc	Protospacer
  ..**  .*****************  ***** * 

208. spacer 80.30|7506404|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020332 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM259, complete sequence) position: , mismatch: 9, identity: 0.735

ccagtt--ttttctctccagcttcccgcgccttatg	CRISPR spacer
--gattaactttctctccagcttccccggccttttc	Protospacer
  ..**  .*****************  ***** * 

209. spacer 80.63|7508781|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 9, identity: 0.735

actcagggataaatcggatattgcccattttcca	CRISPR spacer
aaacgttgcaaaaacggatattgcccatttttca	Protospacer
*  *.  *  *** *****************.**

210. spacer 80.63|7508781|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 9, identity: 0.735

actcagggataaatcggatattgcccattttcca	CRISPR spacer
aaacgttgcaaaaacggatattgcccatttttca	Protospacer
*  *.  *  *** *****************.**

211. spacer 39.1|4395032|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.722

atgtcgcaaacggagcagatggcgcaggacctcttc	CRISPR spacer
gtgtcgcaaatggaccagatggcgcagcagaacgcg	Protospacer
.*********.*** ************ *   * . 

212. spacer 39.16|4396115|36|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to MK017820 (Clostridium phage CPD7, complete genome) position: , mismatch: 10, identity: 0.722

ataatcttaaaaagaatatatatagacaaaaaaatg	CRISPR spacer
ataatcttaaaaagcatatatttagagattttttag	Protospacer
************** ****** **** *       *

213. spacer 39.50|4398607|34|NC_019693|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP049319 (Caballeronia sp. SBC2 plasmid pSBC2-3, complete sequence) position: , mismatch: 10, identity: 0.706

tgttagatgctgcgatagctgacgcttcaagtgc	CRISPR spacer
taaccaccgctgcgatagccgacggttcaagtgt	Protospacer
*. . . .***********.**** ********.

214. spacer 39.50|4398607|34|NC_019693|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP049159 (Caballeronia sp. SBC1 plasmid pSBC1_3, complete sequence) position: , mismatch: 10, identity: 0.706

tgttagatgctgcgatagctgacgcttcaagtgc	CRISPR spacer
taaccaccgctgcgatagccgacggttcaagtgt	Protospacer
*. . . .***********.**** ********.

215. spacer 75.47|7042324|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049816 (Monaibacterium sp. ALG8 plasmid unnamed5, complete sequence) position: , mismatch: 10, identity: 0.706

aaatcaacttgcgatgcttgttaaactgcttgcc	CRISPR spacer
caagttctttgcgctgcttgttaagctgcttgaa	Protospacer
 ** .  .***** **********.*******  

216. spacer 75.50|7042549|35|NC_019693|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026517 (Deinococcus sp. NW-56 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.686

gcaagcgcggcaggggttgatccagggattgtgca	CRISPR spacer
aggggcgcagcaggggttgatccagggtttcgaac	Protospacer
. ..****.****************** **  .  

217. spacer 75.50|7042549|35|NC_019693|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026518 (Deinococcus sp. NW-56 plasmid unnamed2, complete sequence) position: , mismatch: 11, identity: 0.686

gcaagcgcggcaggggttgatccagggattgtgca	CRISPR spacer
aggggcgcagcaggggttgatccagggtttcgaac	Protospacer
. ..****.****************** **  .  

218. spacer 75.50|7042549|35|NC_019693|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026518 (Deinococcus sp. NW-56 plasmid unnamed2, complete sequence) position: , mismatch: 11, identity: 0.686

gcaagcgcggcaggggttgatccagggattgtgca	CRISPR spacer
aggggcgcagcaggggttgatccagggtttcgaac	Protospacer
. ..****.****************** **  .  

219. spacer 80.5|7504592|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046707 (Nostoc sp. ATCC 53789 plasmid pNsp_d, complete sequence) position: , mismatch: 12, identity: 0.647

tttcaaatctggggtgtttgtcagcaagaactac	CRISPR spacer
gttcaaatctggggtgtatgtgagccgccttagt	Protospacer
 **************** *** *** .   . ..

220. spacer 80.5|7504592|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 12, identity: 0.647

tttcaaatctggggtgtttgtcagcaagaactac	CRISPR spacer
gttcaaatctggggtgtatgtgagccgccttagt	Protospacer
 **************** *** *** .   . ..

221. spacer 80.5|7504592|34|NC_019693|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026690 (Nostoc sp. 'Peltigera membranacea cyanobiont' N6 plasmid pNPM8, complete sequence) position: , mismatch: 12, identity: 0.647

tttcaaatctggggtgtttgtcagcaagaactac	CRISPR spacer
gttcaaatctggggtgtatgtgagccgccttagt	Protospacer
 **************** *** *** .   . ..

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1270355 : 1317615	36	Bacillus_phage(20.0%)	plate,tail	NA
DBSCAN-SWA_2	1667210 : 1742727	57	Bacillus_phage(20.0%)	tRNA,transposase,protease	NA
DBSCAN-SWA_3	3444735 : 3506658	44	Streptococcus_phage(14.29%)	tRNA,transposase,protease	NA
DBSCAN-SWA_4	6607210 : 6661213	38	Mollivirus(16.67%)	transposase,protease	NA
DBSCAN-SWA_5	6942853 : 6953551	8	Bacillus_phage(33.33%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_019693|1270355:1317615|DBSCAN-SWA
GTTACACCACCTTAACCCGTTTTAACTCTTCCACGGCCACTTCTAGTTCTTCTATTTCTAGGTCCCCGCTACTGACACTAACATCAGAAATAGAATAGCTCACCGGCCATGCCCGTTTAAACTCAAATCTCACCTGAGCCTGTGCTCCTTGATCATAGAGGGTTAAAGAGCCATCTCGCCGCTGTAACGCCCAAGATCCTTCTTGCACCGCTTCCAACCAATTCCAGACCGTCATAGAAACCGTTAGACCGCGCCGTAGGGTCAAATTGGTATAGCTGATATTGCCCGGAATTTTAGTCCGGATCATCCGCCCTCGGGATTTACCATCTTTGCCCCACATTTGGGGGGTGACTTCGCAGATTTCAATGATTTCCTGGCTAGTTTTAAACCCCTGACATTCCATAAAGTAAGCATCGATCGCATCGACACTATCTTTCAGGTGCAGTTCTAGGTAAAATCGCGAGGTGGCAAGTAATTCAGGAAATTCAGGCACGGTTTAATCTCCAGCAAACGAGTTGCATCTCAGGTGGCGATCGCCGATAGAGCAAGGAGGGGTCTTCCCTACCCGAGGGCGGGACAATCCCACTCCGTTGACTGTCTATCCTTCTGTCATGAAACGCGCTTAGTTCGTGCGTTCCACATACTCATAACAAAACGTGATCGTTTCTTTGAGGGACTGATTTCCCGCCGCATCTAAGTCGGACATTTTATAGGTCATCGGCATCACCCCTTTAAAGGTCCAGCTTGCGGAAGCTGATCCATCTTGCTTAAACACCGTCAAAGTGGCCTGATCAGTTTTACCTTTGGTTCCCGTGGCACCGCCTAAGTCCGGGGTGGAGTGGGAATCGTAAAACCACTTGGAAACCGCTTTCGGGTCTTTACTAGAGGTCACAAATGTCACGGTGACATCGCTCGATTCTACAGCGGAAGGTGCGGCTTGGCGATTGACCTTACTTCCAGTTTTTACCCCAAATGCCCCATCGGCATTGGTCACAGGAATTGACATTTTCACTCCCGAAACCGATTCCACCAATAGATCTTTGCCTAACCCATCGGCAGCAAATTCAAATCTAGCCTGAGAAAGTGGTTCCTTATCGACTGGCATTGTACTCCTCCTTTATTCTTTCCCTAATTACTTTCCCAAAACAAAGCGTTTATTTCTACCCAAAATTTTGGCTTGCTTCTCCCAAAATTTAGAAATCTACTGCTTCCGTTCAACACTTTCTACATTCAGTTCAAATTTTTCCGTCAGAAATTGGTCGCCACTGACATTAAATTCACTGACTTCATAGCTGACCATTTGACACTGTTTGAGGTTATAGGTTAGAACTTCTTTGGCATCGGGGTCGAAGATAGTAATCGCTGCATCGGAAAAATTACCGCTCCATTTTCCATCCCCTCCGTAGGTGGCTGGCAAGCCTTTTTTAAAAATGTCGTAAAGGGTTTTTACGCCATCTTGGAGGACTGCTTCAATGGTAATATTTTGGTTGTTATAGTATCCAGTTGAAACAGTTTGCCGGGACATTTGAGCATTTTTCCCCGAGGCGATCGGGGATTTATGTCCAGCGGTTTTGGCTTGAACATCAATGCCACTGATTTTGAGCAGTGGAAATTCTTTTCCCCCGTAGGTAAAAGAAAACCTATTTGAAGAAATTACAAACAGATCTGCCATTTTTTTACTCCTTGAACCTTGAAATTGAGTGAAAATAGTTGGTGGTCATTGGTCGTTGGTCACTGGTCCTTGGTCATTGGTCGTTGGTCACTAGTCGTTGATGACAAATGACCAAGAACAAAGGACAAATGACCAATGACCAATGACCAACGACTAACTTATTGGCCCGGTGCCCATTGGCTGATGCGGAAGATTACGAATTCCGCCGGTCGCACGGGGGCGACTCCCACTTCGATGTACAAACGACCCATCATCATGGTGTCGGCGGTGTTGAGTTCGCCGTCGCACTTGACAAAGAAGGATTCAGAGGCGGTACCGCCCACCAATGCGCCCTGACGCCAGAGACCTTCTAGGAAGCTGGAAACCGTGCGGGTGACTCGTCCCCAGAGGGTGGAATCGTTGGGTTCAAACACGACCCACTGGGTGCCGATTTCAATGGATTTCTCGATATAGCTCATCATCCGACGCACGGGAATATAACGCCATTGGATGTTATCCGGTTCGGCGAGGGTGCGTGCGCCCCAGATTTTAATGCCGCGATTGTAGTTGGAGAAGTTCCGGATACAGTTGATCCCCAGGGGGTTTAACAGTTCTTGTTCGCGGAAGTTGGTTTCGTAAGCTAGACCAATTACACCCCGGGGAGTATCGTTGGCGGGAGCTTTGAACAGACCCCGGGTTTCATCGGTGCGACACCAGACGCCCATCATGTGACCGCAGGGGGGAATGGCGATGGGACGACCGCCGTTGCGGGGGTTGGCGACTTTGATCCAGGGATAGTAAAGGGCGGCAAACATGGACCTGCGGTTAAATCCTTCGCGTAACCATTTGGCTACATCTTGGGGCTTTTGCTGTTCGGGAGCAACGGCGCGGTTCTCATTTTTCCCGGGTTTGATCGGGGGTGGGTCGAGGACGACCATGCGGAACGGGGGACTGGGAGCAGAGTTTTCACACATACTCACCATCATTTCCATGACACCATGTACCTGGTCGATGTCCATGAGCCCTTCTTGATAGACGCGCATCAGGTCGGGACAGGCGATCATGGCTACGTCGTCAATTTCAAAGATCCCTTGAACGCCGGTGCGATCGTCGCGTTTGCCTTGGAGTTCTCGCGGGAGGCGATCGGGGTCTTGAATGAAGGGGGGGGGAGGGGCAACTTCGTAGGTGCCATTGAGGGGCCGCTTGGAGAGAGGTGAGATGGCTCCTAGACCTTCGGGGATGCTGACATCGATCGCCTCGGATTCCTGCAATGCGGTCAAGACATAGCTGCCTAAGTCGGCCTCTACATCTTCTTTCATGGTCAGATTATCATGGGTTTCCACCACTGTATCCCCACGTTTTACGGTCACTTTAAAGAATTGACCATCGTCAATGGGGGGTTCGGCATCTTCATCTTCTGGAGGCTTCGGCGTACTGCTTTCAACTTTGACCGTTACCCGTCCCGTGGCTGCGGGAAGTGCGGGCGCTTCCCCATCTTCTGTTTCCCCGGCGGCTCCTTTGAGGTTGAATAATAAGGCAGGACGACCGGAGGAGGTGAGCAATTTCGTGGCAGTTTTTTCCGGCGGTGGCGCTTCAGAACCCGGGAGTTTGGTCCCAATACTGCTCACCCAACAGCGACCCCCGCCATTCAAGAACCACCCGTAAACAGCAAAGGGGAGGTAAGCATCGAAGTCGGTAAACCCATCAGAGCCAGGTTTCCCAAAATACTCTAGGTATTGATCCCAGGTGGTCACCATCATGGGTTGAAAGACTTCAGCATCACCACGGACATCTTCCGTAAAGCCGATAAAGCCAGGAACACTGAGACTGACGCCTTCGATCGGGCGACTACCTCGGTCTACTTCTTCAACATAGACGCCAGGAGCAAAATAATCCAAGGGCATGAGTGGTTGTTCTCCAAATTAATAGATAGTTAGATCTACAATGGTTAGCCAACATGAGTGCTTCAAGTCGGTGTGAACCTCCGCAACAATACGGTTAGTTCGCTAACGTTTGTTATTGAGACGAGGTAAAAGCAATTTCCTTCATAGCAGGTTCGGTTTGGCTGGTGAATGGAACAGTTACAGTTAGATACAAACCGGGACGTAGAGGGACGCCTAATGCGGTCCAAATTGCTGCAATTTCACTCAGCCCATCCGCAGAAATCCTCATCGGTAAAGTTCCCTTGCCTTGCAAGGCTGGAGCTAAACGTTCGGACGGTAAACAATGGTACGGGAGGAGAATTGTCAGTGCTTCTGATAACAGATGCTGCTCTCCTAGGGCTGTATTATCCCAAGCTGTGATCAGAAACGAGACATCAACCCAAATGGTTGAGGGGTCGGTCTGTCTATGGGTGGTTTGCATTTGGGGGTTTTCCCGAACGTCGTAGCAGTAGAGGTTGAGCCTCGCAGCCTGATTGTTCAGCCCGGAAGTTGGAGAATTGAAATCAATTTGCTCCATCCTGATCGCTGAGGTCCCGCCTGCCAGGATTTCTGCTAAGGTCTGGGCAACAGCAGGAATCATAAACTTGGGTAATTAGGCAGCTACAGGTTATAGATTAATGAGATTGCTGGACTCTGGTTATTAGACTTTGGTCGAAATTTTAAAATTTGTGTGGAATTCTAGGATTTCTCAGAATCTGAGGTTAAGGTAGGTTTGACTATCCTCCGATCGGGGATTGAGATTATCCCCAAAGAGAACCGACTAGAAAGAAGAGTAGGTATGGAACCGTTGAGTCTTGGAATGTTTTTGTCTCGCTCTCAAGTGCCTTCGACCTCCGCTATCCCGGAATTTTCCTTGGAAGAGACTAGACCCTTGCTGAACCCAACTCCTTCGCGATCGCAATCCCTCGCGATTGAATCAGTCTGCCGCCAACAAATTCAGCAGCTTATCGGCTATCTGCCTTTGGTCGGTGCTTGGATTATTTACTCGGATTTTGAGGCGGAACAACCTCGACGTTGGGTGGGTGAAGCGAGGGGCGATCGCCCTGAATTTAATGAGGAGGAGTTATCTTACCTAAAGTCTGAGGTTTGGTTACCTGATGAGTTGCCGGTTGATCGTCTGTCTCAACTTAATGCTTATTATGTTTACCCCCTTCCTCCCTTAGCTGCTGGGGGTTCTACCGAGTATTTCCCCAAGATCGACTTAGGTCGGTTATCCGATTGTCTCTCTCCTTTGATTGTTCCCCCTGGCGATCGCTCTGGATCTGTAGCGCAGAAGGTCCCCCCTCAGAATCATCCCTCTTGTGCCCTTGCTCAAAGCCGTTCCTATCTCCTGTTATGGTCTACAGAATCTCTCTCTCCCTTCCAGGTAGAATTTGTGGAACAACAGATGCCTATGCTCCACCATTATCTCCGGGGTGCAGTCGTCTCCAACCAACAATCTTCTGAACTTCAATTACTGCGGCAATCTCTCTATAAGGCGGAACATCAACTGCGGAATTCTCTGGCTCTGATTAGCCTTTATGCTGAAACCCTTTGTCTGGGATTACCAACGGGTTCGTTTCAAGAACAAGCTACAGTCATTCGGGAATCGGTGAGTGAACTCAGTGCTAACTTGACTACTTTACTCAATTGTGGTAAACCGGCTCATAAATTGCCGGAACAGCGCCATGATTTACGCCAGATTGTCGAGGAAACCCTTAAATTGATGCAACCTAAATTGCAGAAAAAAGATATCAAGGTTAAGGCTTCTAAAATTTCGGTGATGCTACCCATAGATCGGTGGCAAATCAAACAGGTATTTGAGAATCTCTTGAATAATGCGATCGCTTTTAGTCCCCTCGGTAGCCGGATTACTTGCGAGTGGCAAGTTTTTTATCATGAGGTGCTAGTCTCCCTGAGCGATCAGGGTCCGGGCCTTTCCCGAGAAGACCTACAACAGGCATTTACCCCTTTTTATACCCGACGACCTGGGGGAACCGGATTGGGGTTACCCATCGCCAAAAAAATTATCCTTGACCATCAAGGCAGCATTTGGGTCCAAAATCATCCCGAAAGTGGGGCGCTTTTTTCGTTTACCTTGCCCCGTCATCCTCAATTGGATTAGAAAATTTCAGTTGAGGAGAATTAATAAATTTGGGGGCATTTAAAACTGAAAAAACCAGGATTAATTTAATTTATTTTTGCCTCCTGCAAGCCTTCTTTCAACTTTATTTCAACTTCATTTGTCAATCATTAAATTACCGGATTTCTCAACAATTACTCTCTTGTTTTTTAGAAAAAACCATAAAGCTATGATGACACCTCAGTTAGTTTCCATTCTACTGGTTGATGATGATCCAATATTTCGTCATGGATTAAAAACTCTGCTGAGTTTTTACAATAATAACGGTTTGTTTAGGATGGACGTGGTTGGGGAGGCGGCTTCAGTAGATCAAGCCTTAAAGGTCACTTCCCAGCAACATCCCGCTTTAATATTACTGGATTTAGAATTAGCTCAAACTGATGGGATTGAAGCATTGCTACAATTGCGGGAACAATCTTTTCCAGGTAAGGCAATTGTCTTATCAGCCCATCATGAAGATGAAGCGGTATTTAGGTCCATGCAAGCAGGGGCGCGGGGGTATGTGTTTAAAGAATCTGTGGCGAAACAACTCTGGGATGCCATTGCTACGGTTATGAAGGATGAAGTCTATTTAGCCCCGGAGGTTGCTACGAGTTTTTTCCGCATCTTTCATTTTTATTCCGGTCATTCTTTGCAAGGGTGTAAAAATATCCGCTTAACCGATCGCGAACGGGAAGTTTTAGAATGGTTAGTCAAAGGGGCTTCCAATGAGGAAATCGCCCGTCACCTTTATGTTACGGTGGCAACAGTTAAAGCCCACTTAACGGCTATTTTTGAAAAACTCGGCGTCAGCAGTCGAACTCAAGCCATTGTCAAGGCATTAAAAGTCGGGTTAGTTGCTAGTTAATCTCCCTGGGAACAATTCAGAAACCGGGTGTCTTGCCTCAATTTGGGTGATGTAGCCACAGTTGACGCAGAAACCCGGTTTCTCGCCCCTAGGTTCCTTGTCTCAATCTGAGTTAGATATGTTGTGAGAAAATCAGGTTTTTAAATACTTCCCAACCCCTGTTTTATGGGCATTCCAGGACAATTACCGCCGTTGACACAGAATCCACCGCAACTCCATCGGGGGTTTCCCTTGGTTGTGTAAGGGAAATAAATTTTCACCCTGACACCATTTGATAAACCATCCGGTTGGCGGCCATGCGGCGACTGGGAGATGTTCCCGTTCATACTCTAAAACTGACTCATCGGATAAGACGGTTAGGGGCAATCTCTCCATTGCTGCGGCAAGTTCTGACCGGGTAAAAATACAGGACCAAGTGACTTGAGAGAGTTCTCGGGTGAGGTTGTCTGGTTGATAGTCATCCACGGCTAAGAACAGACTAAATAACAATAAACCCCCCGGACGTAAGGTATCGCAAATTCGGGCGAACAACTGGCGGAGGCGATCGCCGGACCCAAAATGGGAGGCAATTACTTCACAGAGTATCACCCCTTGATAATAGGCGGGTTGTAGCTTGACTTGGCGATCGAGGATATCCCCCAGAATTCCTCGGACTGGCAGTTTCTGTTTTTGGGCTGCCTCTTGGATTTGTTCGATAAATGCTGGGGTTAACTCCACGGCATCCACGGGATAACCCCGTTGGGCTAAGGGCAGGGTATTTCTACCCGTTCCGGCCCCAATATCTAAGATGGGGGAATCAGCAGGATCTGCAAATTGGGCAGCGATTGCCATAACTTTGGCATCGGGATGGGTGCCAAATAAGGGGGGTTCCCGTTGTTTTACCCAATCCTGGTACTGATCGGCGACGGAGGAAATAAACGGCTTGAGTGTCAGGGTCACCCCCTGGGGACTCGGTTCATAAGTAAAAATTAATTTGGAATGGGGAGAGGTGGCAAATCCAGAGATTAACTGGTTTTCCAGTTCTTTCGGCAGTTTGGCGAGGGTGGAGGGTTCGATGACGCTGTTGAAACTACTCAACAAGGCGGCGATCTGTTGCAGATACAGTTGCAACAATTCAGGAACACAGGGAAACAGGATTTCGCCTCTGGCCTGAAACTGGCCTTGCAGGTGTTGGAAGTGTTTCTCGTGAATCTGGGGTGAAGGTTGGGGGATGGGTTTGTGGGTAAGGGCAGAAGATGGGGTTTTGTTAGGCAACATCAGGGTTAGGGGGTGGAGGGGTTACAAACGACGGCAGAGAATCCAGCGCAATTCGATGGGGGGGAAGGCGTTGGGGAGATGGAACATATTTCGGCCTTGGGACCAGGTGGGATACCAACTGGTGGGGGGCCATGCGGAGGCGGGGAGATGGTCCCGTTCGTATTCAAAGGCGGATTCGTCGGATAAGAGTTGCAGGGGGAGGTTCTCCATTGCGGTGGCCAGTTCGGCCCGGGTAAATAGGGTGCACCAGGAGGATTGGGAGAGTTCTACGACGAGGCGATCGGGTTGGTAGTCTTGGAGGGGGAGGAAGAGGTTGAATAAGATGAATCCGCCGGTGAGTACGGCGTCACTGAGTTTGGCGAGTAGGAGGCGCAGTTCGCAGGGGTCGCGAAAATGGGAGATGACTTCGGAGACGATCGCCAGTTGGTAGTAGGCGGGGGGCAGTTTCAGGGGGCGATCGAGGATGTTCCCCGGGATGACTCGCAGGGGTAAGTTTTGGTGATGGGCGGTTGCTTGTAGGTCCTGGATGAAGATGGGGGCGAGTTCTACGGCATCTACGGGATGACCCCGTTGGGCCAGGGGAATGCTATTGCGGCCTGTCCCGGCCCCAATGTCTACGATGGGGGCATTGGCGGGATTGTCAAATTGGGCGGCAATGGCAGTCGCCTTGGCATCAGGATAGGCCCCGAACAGGGGCGGTTCTTTGGTTTTGACCCACTTTTGATATTCTTCCGCCAGTCCGGGAGTCAACAAAGAGACTTGGAATTTTAACTGGGAACTGTCATGGGGTTGGGGTTCGTAGGTGAGGACAATTTTGGCATGAGGGGAGGTTTCAAATCCCTCCTGCAATTTCCTCCATAGACTTTGGGAGAGGTGAGTTACCCCATCATGGTCCAGGGTTTGCCCGAGGGCGTTCAATAGTTGGGCAATGGAGTTGAGGTAATGTTCCAAGAGGGCGGGGATACAAGGCATGATGATTTGACCGCGCCCTTGAAATCGATGTTGGAGTTGGACAAGGGGTCCTGGTTGCAGGGTGGGGGGGTTAGTCAACGGCTGGTTTTCAGGGGTGGGAGAATCTATTACGGGGTCGGAATACATGATGGGATGGGGATTTACAAGGGTTTGCACAGTATCCAAGGCATTGGATCTGGGGTGGGAAAAAAACTATTATGGGGTAGGAATAGAGGATGGCAAGGGCAGTTACAAGCGTTTGCAGAGTATCCAGCGCAATTCCATCGCGGTTTGGTCTGGGGGGGTGAGTAATAATTCCCGTCCGGTTGCCCAGTTGAGAAAGGATTCATGGGGAGGCCATGTTTCTTCGGGGCGATGGGTTTGTTCATAGTTGACCCAGGACTCATCGGAAATCAGTTCTAGGGGCAATCCGGCCATTGCAGTGGCGAGGTCCGATCGCGTGAATAGGCAGGACCAGTTGACTTGCGACATCTGGCGGGTGACTGGATCGGGTTCGTAGTCTTCGGTGGCAAGAAAGAGGCTAAATAGGACTGAACCGCCGGTCTGGAGGACATCACAGATTTTGACGAGGAACAGGCGCAGGCGATCGCGATCGAAGCAAAACAGGGGGAGGGTTTCGGTGGCGATCGCGAGTTGATACTGTCCCAAGGGCATTCGGACCAGGGGATTGAAGATATCTCCAGCAGTCACGGTGATGGGTAATCCCGTTTGTTCGGCAATCTGTTGGAGGCGATCGCCATAGGGAGGGACTAATTCCAAGGCATCCACGGGATGACCCCGTTGTGCCAAGGCTAAGGTATTCCGTCCGGTGGCAGCCCCGATGTCCAAAACTGAGGCAGTCTTGGGGTCTTCTATTAACTCAGCAATCTCCAAAACTTTGGCATCGGGAGTCATGCCAAACCAGGGTTGTTCGTTCTGGTTCATCCACTCCTGATATTCCTCAATATCCGATAAAACAGAGACGGAAAATTCAAAGGTTAATCCAGTTTTTGGGGGGTCTGCCGGATGGTATTTGAGTCTGAGGCGGGCATGGGGAGATAAGGCAAACCCCTCTTCTAACTTTTTGTCCAAAATTTGATAAAGTTGATTTCGTTCCGCTTCTTGGAAGGGGATGGCTAAACTATCGAATAGAGACCCAATTCGATGACGGTAATACTCTGCCATTGCTGGAACTCCGGGCATAATCAGTTCGCCAACGGTTTCCAGTCTTTGGTTAAAACTGGTCAGCATCGCTTGCAAGAGTACATCAGGGTCCGTGATCACTGGCACCGAAGCAGTTGGGTGGTTGGGATTTTGCGATGTCATGGGGTTATCAAGTTTAAAGTCTGTGGATCAACGGTCGGGTGAACGGGGTGCGATCGCCTCCTCTAGGGTGATCCAGATCCGTTCCTCGTTCCCTGAGTTAGCCGGGGAACGTACAAATTGGAGGAACTGCCTCCTCGTCAAGGTATCAATTAAATCCGCAACAACTTACTTGTTTTAAGCTGAGACTACCCAGGGGCGATCGCCTCTCGATTGGCACATTTTTCTAAGCTGATCTGACACCCCCGTATCCCTGAAAAGTTTACCTCAATTTTTCCAAGATGGATAAAATTTAAACTTTGCTTAAGTTTTGTCAGTCTCTGCCTCTGAATCGGTTATCTTCAGAAAATTCCGGCCTGATTTTCATCAAAAATCTCCCCAGCGGTTGTGTTAAACTCAACCTGATGAGTTGACCCCGATTCACCTATTAGACTCAATCCTCATTTTAGTATCAGCCCAGAGTGCATAATAATATGAGCAATTATCTGGCTATTGCCACCGTGACTGCCTGTTTACAACGAATGTTACAGTCTTCTGTGCAATTAGATTTAGATGGTGCAAGAGTCACCACCGTTCGCCCCAATAATTTAGGCAGCGGGACTCCGGAAAAGGGAGTTAATCTTTATATGTACCAAGTCTCCCTCAATCCCGTGTGGCAAAAGAATGCAGAAGTCCGGATGCGAAGTACCCGGGATGCGGGGGCGAAGAAATCCCGGACCGCATTAGATTTGCATTATATTCTCAGTTTCTACGGCAATGAAACAGAATTAGAACCGCAACGACTGTTAGGCAGTGTGGTGAAAATTTTGAGCGATCGCACCACCTTGACCCGAGAAACCATTTACGAAACTCTGGCTGATTCTAGCTATCCCTATTTAACCGATTCTAATTTGGCGGACCAAACCGAAGAAATTTGCTTTAGTCCGATGGATTTATCCTTAGAAGATTTATCAAAAGTTTGGTCAGTCTTTTTTCAAACGCCTTATAGTATTTCCTTGGTATATAAAGCAACGGTGGTGATGATTGAAGGAGAAGAAGCGGCGTATCGAGCTTTACCTGTGCGCGAACGTGCTCTTAGTGGCGTTATTCCCTTTATCAATCGCCCCCTGGTGGAACAAGTGGTCTCTCGTGCGGGAAAATTTGAGCCGATTCTAGCCAATAGTACCCTAATCATTCGTGGCAAAAGCCTCAACAATAAACAGACAAAAGTGCGGATTAGTGGGGTGGAAATTACCCCTCAATCCGTCAACGAAACTGAGCTATTAGTTCCCCTTGCTTTAACTCCGGATAACTCTCTCAAAGCTGGGGTACAGAGTTTACAGGTGATTCATCATGTCTCTACCGAATCTCGGGGAGAAAATGGCAACGGATGGCAGGGAGAATGGACTCATGAAACCGCGACCCAAACCTTATCCAAACCGACGGTATTTTCTCAAACTTTAGAATCGAATGCCATTCCGTTTATTTTACGTCCTGTGGTGACAAAAGTGACGGTTTCTAAATTGGAAGGAAAGGACGAAGATGTGCGATCGGCTCAAATTAAGGTCCGGGTCAATCTCAACCTGGGCAAACAGCAGCGGATTGTGTTAATTTTGAATGAAAAATCAACTCAAAATCCGGCTGCCTATATGTTTGAAGCACCCAACCGTCATCGGGATGGGATGATGGTGACGATTCCGGTTAAAAATGTGAAACCGGGTGAGTATTTGGTGCGGTTACAGGTGGATGGAGCGGAAAGTATTCTGAATGTGGATTCGGATCCGAACAGTCCTAATTTTAATCGTTATACTGAGCCTAAGATGGTGATTCGGTGAGGGGATTGGGAACCACTGATTTCACTGATTTTCACAGAAGAGATTGGGAGGATGAATTGGATGAATTGAGATGATTGATGGATTAGGATGAAGGACAAATGACCAATAACGAAGGACAAAATCATGAATGAAGAAGAGTTGAAAAAGCGGCTGAATCAAGAACTTGATATGATGAGTATCAATCAGTTAAATGAGTTAGGGAATCAAGCGGTTAAGATGGGGTTGATTGTGGGTCATGGATATCGCGGGGGAAAATATGAAATTTTGCGGAAAGGGGAAGCATTAATGATGACTCCCCAGGAAGCTCAGAGTTATTTGGAAAATTTGATTAAAGAAATTGGTGGCTAAATGTCTGGAGTCAGAATGAGTCCGACTAAAACTTGGACGATCGCCAATCAAGAGTATTTGATGGCGGCGATCGCCCGGGTTCGTTCCTATTTACAGATTCACATCCAACGCCTGAATCCAGAGGCAGAATTTGTTTCCCTTGAGGAACCGGCAAGGAGTTGGGATTTGCCAACGCCTCCGAGTTTAGATGAACTCAGCGATCGCTTTGGTTTATCTGGTTTTGAACGTGACATCCTGTTATTATGCGCCGGGATGGAACTGGATGGCACTTGGGGAACACTCTGTGCTACTGCTCAAGGAGATGCTCAAGCCCAATATCCTACCTTTAATCTCGCTTTAGATGTCTTGCCGTCACCGAATTGGATGGCACTGACTCCAGTAGGAGGATTGCGGCGTTGGCGATTGATTGATATCGGAGTGGGGAATGCTCTGACCCAGAGTCCCCTGAGAATTGATGAACGGGTGTTGCATTATTTAGTCGGGATAGAGCATCCCGATGAACGATTGGTGGCAGCAGTCTCCCGCATCCCCATCCATGTGGGGGAAATGGACCGTTTATGTGCGTCCCATCGCCAGTTGGCGGAACAGGTAGCGGGAATGCTGGTGAGTGAAGAGTTGGGCAAAGTGCCGATTGTTCAATTATGTGGCAGTGATGTCGCCAGTAAGCGGGCGATCGCCACTGCCGTCTGTAGTGCGATCGGTTGGAACCTGCACGTCATGGCAGGGGATGTCATCCCCATCGCCTTGGGAGAAATCACCGAGTTGATGCGGTTATGGGAGAGAGAGGCATTTTTAAATAACAGCGCCTTGCTATTAGACTGCGATGAAGTGGATAGCAATGATGTAGCCCGAGAAAGTGCGATCGCCCGAATTATCGAAAACTATGATAATCCCTTACTAATTACCAGTCGCGATCGCCGCCATCCCCGGCAAAGACCCTTAATCACCTTTGAAGTCGAACAACCCACATCCCAGGAACAACGGGAACTCTGGGTCAATACTCTGGGTCCAGACGCTGCCGAGTTAAACGGTCAGATTGAAACCTTAGTCTCCCATTTTAGCCTCAGCGCCCCCGCCATCCGTGCCGCCTGCCTCAAAACCAAAGGAACTAACAAGATTGCCACCGACAACAGCAACGAGTTCGGCAGCCAACTGTGGGAGACTTGCCGCATCCAGGCGCGATCGCGCATGGAAGACCTCGCCCAACGCATCGAATCCGGTAGTCAGTGGGAGGACCTCGTACTCCCCGACATCCAACGAGACACCCTCCGCGAAATCATCGCCCATGTGCGACAACGGGCCAAAGTTTACGAAACCTGGGGATTTGGCGGCAAAAGTGGCCGAGGATTAGGCATCACCGCCCTCTTTGCCGGTGCCAGCGGGACCGGCAAAACAATGGCCGCTGATATTATCGCCCAAGAACTGCACCTAGATCTGTATCGCATCGACCTCAGTTCCATCATTAGTAAATATATTGGCGAAACCGAGAAAAACCTGCGCCGAGTCTTCGACTCAGCCGAAGCAGGCGGGTCCATCCTCCTCTTCGACGAAGCCGACGCCTTATTTGGCAAACGCAGCGAAGTCAAAGACTCCCACGATCGCCATGCCAACATCGAAGTCGCCTACCTCCTGCAACGCATGGAAGCCTATCGAGGATTAGCCATCCTCACCACCAACCTCAAAAGTTCCTTAGACCAAGCCTTCCTCCGCCGCATCCGCTTCGTCATTCAATTCCCCTTCCCCGACGCCAATCAACGGGAAGAAATTTGGCGACGCATTTTCCCCAAACAAACCCCAACCGAAGGCTTAAATTATCCCAAACTCGGTAAACTCAACGTCGCGGGCGGAAACATCCGCAATATTGCTTTAAACTCCGCCTTTATTGCCGCCGATGCTAACGAACCCGTGATGATGAAACATATCCTCGAAGCGTCCAAAAGTGAATATATGAAATTAGAACGACCCTTGACCGATATGGAAGTGAAAGGGTGGATTTGAACCACAGATTGCACAGATTGGCACAGAGAAGAAGTCCCCACCTCCCACTCCGTAACCCTCTCCAAATCCGTGAAAATCAGTTTAATCAGTGGTTAATACTCTCTTCATCCAATCTAAATAAACCGGAGTTACCCTTTCATGAAATAATAAAAAAAATACTCTATTAATACGATCGCTGAGGCGAGACTATGGCAACCGGACGGCAGATTCAGAAAAAAGCACAATCGAACGCCACGCCGACTCCTGTCACAGGAATATTCAAACCCCGTCCGTTTGCCCGGGCTGCCGAACCCGAAGCCGCAACCGCACCGGAACTACAAACTAAAACAGAACTGGGACAAGTCAGGGGCGATCGCCTCTCGCGCATCGACTTTTCTACACCCCCACCTATCCAACCCAAACTGGCGATCGGTGCACCAGATGATAAATACGAGCAAGAAGCCGATACCATTGCGCGCAAAGTCGTCCAACAAATGAGTACCCCCACCCCCCCGGATGCAAACGGAGGTGGGGATGCTGTACAGCGTCAAATGTTCTCCACACCTTCAATCATGAGACTGACGGTACAACGCCGGAAAGCCAGAGAAGGAGGAGAAGCCTCATCAGACTTAGAAAGCACCATTAGTCAAGCTAGAAGTAGTGGGATGCCTCTAGGTGAACCGATTCGTCGGCAAATGGAGGGCGTATTTGGCGCTGACTTTAGTAGCGTCAGAGTTCATACCAATAACACGGCTGACACCCTCAACCGTTCCCTGAGTGCTCGTGCTTTTACTACAGGAAACAATATCTTTTTCAAGCAAGGGGAATACAATCTTAGTAGTTCAAGTGGTAAAGAATTACTCGCTCACGAACTGACTCATGGAGTACAGCAGAGTGGCAGTTCCACTATTCAATGCAAGCTCACCCCTGACCAGATTAAACACGCCAACCGGATTCGCAAAGCCAGAGGTCTAAAACTACTCCCTGTGGAAGAAGCACAGGACCTTAATACGGTTGAAGAAGCCAGCGAAGCAGTTCCTGCCTCAGTTCCTGCTGCCTCGGTTCCTGCTGCCTCTGCCCCATCTCCCCCATCTGACGCGAAACGGAAAGGCGCTCAATTCAACATTATTCAAGATTATTCCTGGATCCGAGATACACTCCAAGAATGCCAAAGTTGGGATAACATTAAACAAAAATTTGCCAGTCAGAAGGACAGTATGTGGCAATTTTTCGACTTCCGACAGTGGTATGTAGACTCATTGATTAATGTTCTGCGGGATATGTATCCGGGGTTAATTGCCAAATCTGTCGGCAGCCAAGACCCCACCTCAGACTATGACATCACGATTTCTACGCCGGGTTCAGGAGATGATGTAGAAGCCATCCAATGGTTTAACACTCAAGTTCGCAAAGAATTTGGGGTGGAACCGGGTACTTTGTTTGATACGAACTTGTATGCGAAAGATTACCTTCAAGTTAAAGAAAATATCGACGAAACAGCCATAGCCGAGCAAAATTCTGATACAGATCTGGAGCAACCGGATGGCGCATTTGGCGCAATGGGTCACCTGTCTCAGGATGTTGCGGCTTTAGTTAAACAACGTCGGTATATGAAACAAGTAGAATGGGATAGATATGTTGATGATGTAGTTCAAAGTATCAACGACCCAGAGCGAAAAAAATTAACCCGTCTTCAGTATGAAGAAGCCGATTCAGTGTATCAAATTTTTGCCCATGAACTGCTGCAAGAAGTTGAAAAAGAATCAGGGTTACCGGAAAAAATAGAGGAACATAGTATCAAATTAGGTCCGGAAGAAGAAGCAGCCTTGTCTCAAATTAAATCCCCCGATGATAAGCTGAGATCTATAATCCGTCAACAATTATTAGGGTCAGAAAAGCTACAAGCTATAACTCATGACAACCCCGATTTAGTTCTTCAGAAGAGTAACGAACTTTACCTGACACGGATGAGAAAAGTTCGTCAACTCCAACTAACCATTCGGGAGTTAGGCACGCAAGATAAGTTTGTCGAACAGGTTAAAGTGCTCAAAGCGCAAGTTAAACAAATTTTAGGAGAAGCTTGCTTTTTTGCCGCAGAAGCCTATCATAGCGAAGGAGCCGTTAAGCACATTGTAGCAGGGATTCAGGGGGCCAAGAACCCAGAACAAAAAGCAGCCATTATGAGTTCGCTCAAGCCCGAACACTTTTTACAATCCTTTAATGAGCAATTGGGTGATTTCCTAAAAGATTTGAATCATTATGCCGGTGAACCAGACGGTAAAATTTTCTATCGGTCTTCTAAATACTTGTATCGATTATTTTTGGCAGTGGCCGAGTTGCGTCAATACCAATTTACAGAGAATAATTTTGCGTTGAAAATTGAAGAACAACGCGGAAATTCTGATGAAATTGCCAAAAAAATTAATAAAGATTTAGTGGAGATTCGGAAAGGAAATAAAGCCGACCTGGATACGGATGATAAAAAAAATCAAGCCGCTGAAGCAGCGATGCAGACAATTTTAGGGGTGAATAAGGCATCTGAACTCAAGATAAAAATTTTACAGATGTCAACGGAATTTAATACCCTAGTTCGGACTCGGGCTAGTGAATTATCAGCCCCTAGTCTCGAAACTTCCCAAACTTATTTCGGAAATATTGTCCAGAATTAGATTCTGGGGTGGGGAAGCTATCGCTGCGGTTTGGGGACCCTGGATAAAGCCAGAGGGTGCTTTGTCCATAGGACCCGATGAATCGTTTTGGAATCGGGGGTCCAGTTTTTAATCTAGACTTTAGTCCAATGGAAATAATCCCCTGTTGATGAAATACTAGACAACATACTCTATTCAATTGCGATTGCTGAGGGGAGACTATGGCAACCGGACGGCAGATTCAGAAAAAAGGACAATCGAACGCCACACCGACTCCTGCCACGGGGATGTTCAAACCCCGTCCTTTTGCGATGCCTGCCGAACCCGAAGCAGCAACCGCACCGGAATTACAAACCAAAACAGAACCGGGACAAGTCGGGGGAAGCCGCCTCTCGCGCATCGATGTTTCTGCACCCCCACCGATTCAACCCAAACTGGCGATCGGCGCACCGGATGATAAATACGAGCAAGAAGCCGACACCATTGCTCGCAAGGTCGTCAAACAAATTAGTACCCCCACCCCCCCAGATGCGAACGGAGGTGGGGATTCTGTGCAGCGTCAAATGTTCTCTACTTCTTCAATCATGAGACGGACGGTGCAACGCCGGGAAGCCATAGAGGGAGGAACAGCATCATCAGACTTGGAAAGCACGATTAGTCAAGCTAGAAGCAGTGGAATACCTCTGGGGGAACCCATTCGTCGCCAGATGGAGGGGGCGTTTGGTGCTGACTTCAGTGGCGTCAGAGTTCATACCAATAACACGGCTGACACCCTCAACCGTTCCCTAAGCGCTCGTGCTTTTACCACCGGGAACAATATCTTTTTCAAGCAGGGGGAATACAATCCTAGTAGTTCAAGTGGGAAAGAATTACTCGCTCACGAACTGACTCACACCATTCAACAAGGTTCAGTTCAACGTCAAGCTACGTCAATACAGCCAGTTTCTTTAACGCCTATCGATCCAGGTGTTAATTCAACAATTCAAGGTAAGTATTTAGAGAATCAACAGCTATTTTCTAAGGATACAAACTTAGGGACCTTTTATAGTCGTGGGGCATTGGAAGCCGTTGATGAAGCATTGAAAGCCTATGAGAAAACTATTATTTTTCCTGAAGTTAAGGATCCAACCCTAGCGAGTAAGCCTGAACATATTGATGAAAAACTTAAGAAATTATTCAAGTTAAAAGATGTTGTTGAATTTTGGGTGTTCCAACACTTTGATTTAAAAGATGCATCAAAAGCCAAGACCACTCGAATTAATCCTACCCTAGATTTACAAGAGGAAATTACCCAAGCTATCAAACAGCAAGTTAAAGTTTATAACCAGGTCAAAGGATTAGATGCTTCTGACCAAGATGTAGAAGATCGGCTACGTTCGGACAGCATGGACTCGGCATTAAAGAGCAGAGTCGCTACTTTGATTGATGCCATTTTGCAGCCTGGAGCGCTGAGTAAGCTATCTGCCGAGATATCTTTAGCCATTGATGTTCAACCCCCAGGTTATGTGGGCTTCGATTTAGGCTTAGATGTTGAACGCAAAGAAAATGATGTACTCAATATTCGCTCAGAATTGGCAGCTACAGGAGGTGTCCGAGTCCCGAAAGTATTTGATATCAAAGCCAAACTGGGTGGCTATGTTGAAGCAGAAGCTGGTGATAGTCGGAAGACTATGAACCTGATTTCTTATGGTTTGTATCGGAAGGTTGTGGAATCAAAATTAATGCCAGCCAGTGTAGCGGGTGTAATTTGGGGAGGAAGTTTCGGAGAATCCGGCCAAATTATGGCCGCCAAGTTAGCAGCTGATATTGAACGAGGTGTTTTCGGTGCCGAAGGTGGGGAAGAGGCTTTTGTCGATCTCGGACTACTAGCTGGTATCGGCGCAGAAGTTGGGGATAAGGAAACCCTAGGAGGCGGGGTAGAATATAAGTACACAACGGGTCAGAAGTACACTAAATCATCGGTTGAAAGTGCCGGCGGTTTAGGCAAAGTTACTAAAGAAGATGTCGGGAATCAAGGGAAGAAGAGGAAAGGAGAAGGAACTAGCGCTCATGAGTTTACAGCCAAGCTTAGTGCTGGTATTTTTAACGGGAAAGTAGGCTATAAGAAATCCGGTGAATCCCAGGAAATTACTGGTTCTGCTCAGTTTTCTGGTATTCCGGATATCGTTTCTTTTGTCTTGGGCGTAGAGGGTACTATTAATAGCTTTAAGTCGGCCTACAAGAATAAAGAGAAAAGCAAAAAGGCGAGTGATACAATTCAGGGGCTGGATGGTTTAATTGGTACTCTTCAAACTTTAGCTGGTGATGGTGCAGCAATCAGCTCGATTCCCACAACGAGTACCAAGGGTGAGTTTGCAATCAAAGCATCCAAAGAGGGTACTTCTGCGTGGGTGATTGAAATAATGTTCAATCAAATCACTGGCGCTCCCATTCCGGGGGATTTAGGGGTTGTAAGTGTGGAAGTTAGTAAATCGGACACACGCCTTAAGTTCTCAAATAAGGGTGGTAGCTGGAAAACTGTACATTTTGGATAAATCATGGCTACAGAAACACAACATTTAACTCGTCAGTTTGAACTTAGCTTTCTATTAGATGCTAAAGATGTCCTAAGTGCTAAGGTAGTTGATTCAAAACTTTTTTTGGTTAACCAGGAGCCTAGAGAGTATCGAATTACCTTGGAAATAGACTGGCTGGAGTATCAGAGAATTGTGCAAGCGGAAGGCTTTAACCTGACACAGGCTGCTCGATCGCAAGCTGAGGCTCTTTCCTTTGATGAAAACCGCCCCCTAAAAATTGAACTGCGGTTGGATGAAAACTTATTTCCAGATTTGATTCAGAATGGGAATTCTGTAGAAGAACTCATGAATTACTTGATAACCCGCAATCAAGCTAATAAAAGTTCTGACTTCTTCAATGCACATCACTGGTATGTCTTGGATGTCAACCAAGGGGTTCATCTTCCTCCTGATCTTGAAGGTGTGGGGGAATTAAAAATGGGATATCGCACCGCTTGGGCTGATGAAAAGAATAAACCCGAGGATGTGATTAAGATTGGGGATTCCAGAAAAAGTTCACAGATGAACGCGGATCACCCGATTTTGGAAATAATTACGGAAGTTTTGACCCAGAATAATCAGCCGCTTTACCAATGGGAGAGTGATCATGTTGTGAGTTTCCCCTATCAGGGAAAAAACGAAAAATGGCGGTGCTATGCAGATGCACGAGAGGAGATGTCTTTGTGCTGCTTTTACTCCATTTTTCCCGATGCGGTTCCCATAGAAAAGCGTGCGCCCGTTGCAGAGTTATTAATGAGAATTAATTACACCCTCACGGTCGGTAATTTTGAAATGGATTTTGAAGATGGGGAAGTTCGGTTTAGAACCAGTATTGATGTGGAGGGCGATCGCCTCAGTACACAGCTATTCAGACAGTTGACGATTGCCAACGTCACTATGATGGATCGCTACTTACCCGCCATCCGAAATCTTCTCAAAAATGATATGTCCCCCACCGAGGCGATCGCGGCGATTTGAAGACTAACCCAACGGTGCGATCGCCTAAGCCACACACTTCACCTCTGAAAGCGTCTCAATCCAAACCTTCGCCCCACAGTCTTTCGGCTGATCCGGTCGATACACCACTCGGCATGGCCCGCTGACTTCTACCTCATAGCCATATTGATTACTGCTGCCGCGTTTAACCCCAATGACCGGCTGATTTTCCCCATGCTTGTAATTTTGGCTAATCCGAGTCCGGTTGACATGAATGCAAGTCATCACTTCCCGGCGGATGCCTTTCCACGTGGGCTTTGGGCCGCGCGTCCCCTTGGTAATTACCGGCATTCCATCTTTCAGGGGAATCACCCAAACATTACTAATTTTATAGGCTCCATGAACTCTTCCATCCAAGAGCAACCGTCGGACGCGATCGCTGGAAACTCCCAGTAACTTAGCGACTTCTTTGGTTCCAACTAGCATGGCAACAATTAAAATAACAGCATAATAGTTTATTTTGGCAGGTCTCGGCTAAGTTGTCTAGCCTGTTAGGGGATTGCAAAATATAAATCCTCCAAACGTTCTGAAAGTAGGGGCGTATTGCATACGCCCTCCGGAGGGCGTATGCAATACGCCCCTACATAGATGGGGCTACTCCGTTGATCTACGAACGAACGTTTTGGAGATTTTATTTTTTGGAGTTCCCTTAGCGACAATAATTTGGGACCCTAAGCGATCGCCTCTCCTCTTCTCCCAAAGTCCCCTCTTTGAGGGCAATCCATCAGGCTCCCATCCCTGGCCCAACCTCCGGTCAATTTTGGCGATTTCTCAGTCTTTTGGAAGAAGAATGACTAGTTCACCGATGCCAAACTAGAACGATAATTTCTCAATACTTCCGGAGAGCCTACTTATGGCTACAGGAGAACGTATTCAAAAGAAATGGCCTAACCCTGCACCCACTCCCAGGGTGAGGCCGTTCGCGTTACAGACTCCTAGGGAAGTGCCGCAACTCCAACCCCAAGTACGGGAAGCCCCGGGCAGCCGCAGTATGCCCAGCTATAGCGCAGGCGATCGCCTCTCTGGCATCGACTTTTCGGCTCAGTTCCCGATTCAACCGAAACTGATCACCGGCGCACCCCAGAATAAATACGAGCAAGAAGCCGACTGCCAGGAGGCGGGCGAATCCATTCAGGGTAAGCTGTTCTCCTCACCCCAGATCCAGCGGAAGATTGAACCGCAGGAACAGAGCTTTACTCCGGTCTATTTGCAAACTAAGCCCCTGACTATCCAACGAGATAGTGGCGATCGCACCGATGCCCAGCCGCTAATTAAATCCGAAGATATCGAATATGAAATCATCGGTCACCGTTTTGCCTATCAAGGAGACACCCTCCCGGCTGCCGCAGGAGATTGGCTGGCTACCCGAGGCTACCAGCGAAACTGGACTTTGACTATTCGGGGTGAAGGCTTTTTTATGGGATTACTCATGCCGCTAGAGGATGGAGGCCGAACTCCCATTCTGGCTTTTAAAGGAACAACCCCGGATTGGGTCGATGTCTCCGATATCCTGGCTGATCTCGATCCGATCGCCATTGGTTTCACCGCCTTCAAAAGACAACAGAAAAAAGTTGCTGAGGCGATCGCCACTGCCGGTGGCAAAGTGGATGTGGTGGGTCATAGTCTGGGCGGTGCTCTGGCTCAACACGCCGCTTCTGCCTTCCCCAATAAAGTTCGTCGCGTTGTGACCTTTCAAGCCCCTGCCATCAATCGCATCCAATCCTATATGTTTGGCAAGTTAGATGCCAGTGAACGTCCCGAAGAAGTCCGGCATCACATCGCCACCGGGGATATCGTAGATGTTGCCGGGGGTAAGCATCTGGCTGGAGATGTGCTATTACACCAAGTCGGCAGCAGTCCGACATCACATACTAAATATTTACTCAATAGCGATGCCTTCAAAGACCAGCGCGATGCCCTTGGATTAACCGATGAGATGTTAGAACAATTAGGCGTTGCCGAACATAAAGCTAACCATAAGGGCAAAGTGGAGGAGTTTGAGGAATATCCCTATTGGTTCCGCCAAATTTTAACGGAATGGGGCGGCAGAACGGTATTGGGTGCTGTGCCGGGTGCGTTACTCAGTGCCTACCGAGGGGGACAGAAAATAGGGCGTGGCATTGCTGCGGGTGCTTCTTATGTGGGGGATAAAATTTCTAGTGGGGCTTCTAGCATTTATGATTCGACGCGAAATCTCTTGAAAAATCTGTTTTAATCTCTGATGCAGCCATCACCCAGGATTCAGTTGACCCATTATTACAGTGAAGAAATCGGTGTCTCCCTAGAACTCCCAGAACATTGGCAAGAAGGCGAAAGCAATGGGGAACGGGTGAGCTATAGCTGTGCCTCGGACGGCCCATATCATCCCCAGCTTTTAATTCAACGGGTTCCCTTGTCTGGGGAACGGGTGTCCGATGGGTGCGATCGCCTCGCGGAAGAATTGTTGCAGTTGTACCCTTCACCCCTAGAAATGGGCGATCGCCATTCCCTGACTGTTGATAATTTTCCGGCGAGACTGGATATTTTTAGCTTCTATGACCCGGAATTTAACATCCAGGTGACTCACTATCAAGTTTGTATTCAACTGCCGGATGCCCTTTGCAGCGTGGTCGGAATCGTCGAGGGACAGTCTGCCGAGTCATTGCTGCCTGTTTTTGAGCAAGCCGTCGGCTCAATTCGATTTATCGGAATGGGAATGGGCAGAACAGCCTTAATGAGTGACCCATCGACGCGAATTAGTTATTTTAACCCCGGATTGGGGATATCGATTTTGATACCCGCTTCCTGGTCAGTACAAGAACTCCAGGAGAATCAATTTCAGGCGATCGGCCCATCAGTTCCAGAATTTGATGGATATCACCCTCGCATCAGTTGTACCCGTACAATTCCCACAAATCAGACTCCAGCCGGTTTGGAGGAAGCGATTCGCAAGTCCGAGACAACCCACCGCCTCCTCTATTCAGACTATGAGATTCTGAAACAAGAGCGGTTTTCCCTAGGACCGTATCCGGCCTATCTGCGCCAGATGCAATGGTCCTATCAAGGAACGGATATTTATTTGGTGAATGTCCAAGGCTTAATTTGGACCCCCAGCAGCGCTTATGTGTTTAAGGCGGAAACCTTAAAGCAATATGAATCTAGGGATGTTCCGATCTTCGAGGCGATCGTCAAATCAACTCGGATAATTCCTGCCTCCTGTCCAGATGTCTGACCCAACCTTAGAGGATGCAAGAACTCTACGGTTGGGCAATCTGCTGGGTAGGAAGCCGCTATTGTAATCTTTGATTCAATCGTGGTAGTTCACGAAACAGCTTGGATATCAATGCCACACTCATCCACAAGATAGCACAGCGCCCGGAATCTCAGCCCCATCAGTTGCTCATAGAAGGGATTGAGCTTACATAGAGGGGGAATGTGGAGAATAACACGACCCCCGATTTTGATATCTCGGGCGAAGGGACATTGAGCGGGAATCAATTTATAGAGGAGTCGAGCAACATCTGGGTCTCAAATTTCAATCTGATCCAGCCGTTGACGCATGGGTTGGGAGAGAGTAAACAAGAATTTCCTCATAACAGCACCTCTGGGGAAGCGATCGATGTTCAGTTGGGTTATAAATGTTTCCTATAATTTAAGGTACAACACTTAAGAAAAACTTGTGTAAAGAAATTGTAAAGCCTCTCCGCCTATTGTGAAGTTTATGTGAAGCGTGCGGAAAGTCTGCCTGCTGGCGATCATCAAATCAACTCGGATAATCCCAGGCAAGTCGTATAACGACCTCTAGCGTTTTAGTTGCGATTTCGGTTGAGGGTGGTAGCCGCCCTTTAGGACTTGCCAATTTACCAATAGTTGAGGGAAAATTTTCTGGAATGTTCAGATGGAACAACTATGAAAAAAGGGGCAGTAATAGACTTAATGGAGATCTACCGCTACTCGTTATGGCGGGAGTGGGACGCTAACGCTCCAAGGGTCGCCTTTGTTATGCTTAATCCTAGTCGTGCGGATGCAACTCATGATGACCCTACGCTGCGTCGCTGCATCAATTTCGCTCAGTCTTGGAATTATGGTTCGCTCGAAGTGGTCAACCTATTTGCTTACCGAACTTCAAAACCAGCAGAACTAAAAAAGGTGACAGATCCCATAGGGTCAGAAAATGACTACTATCTCGAAAAAGCTATTAAATCAGCGGATAAAATTATAGTAGCTTGGGGGAATCATGGCATCATTAGGAACCGTTATAGAGAGGTTCTCGATTGGCTAACTAGCTTTGATGAACTCTACTGTTTGGGAATTACCCAGAGAGGCTATCCACGCCACCCACTGTATGTTAAAAGCAATACAAAGCCTGTCTTTTACAAATCTAAATAGACTTAAATTGGTTTTTACATTTTTTGGGCATAAAAATAAATGCCAATATTTTATCGTTTTCTTTAGGTAAAATTTAAATTAATTCCTATTATGAATATTATTGGTCATGGTATTGATATTATTGAAACCCAACGTATTAAAAAAATAATAGAACGTTTCGGAAATCGTTTTGAAGCGCGATGCTTCACCGAAAAAGAGTGCTTTGCTGCTGAATGTAGTACGAACCGCGTCCAATACTTTACAGGTCGTTTTGCAGCTAAAGAAGCGGTACTAAAAGCTCTTGGTACAGGGTGGGCTCAGGGAATTTCGTGGACTGATATTGAAATCGAACGGTTATCAACAGGTAAACCGTTAGTAGTTCTGTATGGCAGATGTCAAGAAATAGCAGCGGACTTGGGTATTGCAAGGTGGTTCTTGAGTATAAGCCATACAGACTCCTATGCGGTAGCAAGTGCAATTGCCTTGGGTTCAATGTTGGTTCAAGCAGATTTATAAATTACCGAACCAATAAAGGAATCGTCTCAATTATCTTGATAGATTATCGAGCGTTCATCAAGGTTTACAACAACATTTCCACCGCGCTTTTTTTCTACCTGTCGCCAAACTTCGTACCCGTTCAGGATAGCCTTTTCCCAATCCCCAAGCGAACAATTAGCAACTTCTAAGTGTTCGGTCATATTTTTGATAGTTTTCAGAAGTTCGTAATCCAGAGTTTTAACTCCTTCTAAGAAGTTGTGCTTGTTGGCATAGCTAAACACGAGTGCTGATATACCTTCCTCAATGGCTATTGCACGACCGCCATCTTCAACTTCGTCAGTTTTGGAATCGCTTTTTCGCTTACATTTAAGATTACTACGAATGACTGGCGACCAACCCAAAACTGCGGCATAGGAGAAATGAAAAATGTCGTGAAAGCGGTAGCCATCGCTTGAGTATGAGTTATCAGTAAGATCGTTTCCAATCTGTTCTCCATTAATAAATGCTTTCATCTTGACTGAGTTATTTTCACTTACCTCCGTAATTTTAACCACAAACTGACGTGGTAAGCGCTCATGTTCTGGAAAATCACTGTCAAATATGTACGCACCTGTTTCTACTAAATCTCTCCATCCCCAACGATCGCGGCATTTTTGAATATTACCTTCCGCAATTTCTTCCAAATTAAGATTAAACTTGCTAGATAAATTAGCAATATACCAAAGTAGATCGCCCAATTCTTCTGCAACCCGTTCAGGGAAAAGCTTATGAGCTTCGCCGTCACGGAGGTACTTTTTGTACTCACTGAGTAACTCACCTGCTTCACCTGCTAGACCGAGCAGGGGTACAATTATTTTGGTATCATTTTCAGCAGGAATATGATCCGTCTTGAGTGCTTCTTCTTGATATTGGCGAAAATCCATTATCCACTCCTTTAAATTCTATTTAAACTCAAACTAAATATCAGCCTTGATTTTTTTGGATTCCTTAATAGCTTGGTTAATTCCCCACTTGGGTGGATACCAGTAATCTAGTGGTTGTCCTTTACCTGAATACTTCTGTTTTATGCGAGTCCGACCTGATATTCCTGAAATATCAGGATGTTTCATTCGAGCATATTTATCGACCTCACAGAATAGATTTTGGCAATCGATCAATTGCAACTTCCTTCCCCAGAGAGACTGAAAATTGAGCCCTAGCCGCTCAAACTCAGACTCTTGAATATCTGCCATAAACTTTATAATTTCTGATTCGTTAAGTCCACCGAGGTCAGAAAAGCATTTGCGAATCCCATCTAGCGCCCCTGGTCCAGGAATAACAAATTCCATCTCGCTAAAGTTAGTAATTTCGCTATAGTTAACATCAGTAATGAACTGGTATGCCAAGAAATCGCCGATAGTTGGATAGTCACGTAGCAAATCGAATCCTTGATGCATAGTTTTAGCATCGGCAAGTTTTTTTGGTAAATCATTAGCCATCATCAACTCGATTAGCTTGAGGTGATTGCGGTGTTTTGCAGCGTTTCCGAAGCTTGTTGCCCCTGACGGCATGATGTATGCCGCAGAATAGATGGTTTGACCTGACTGAATGGCATCAGTAAGAACTTGATCATAGCGTTCAAAGGAATATTCCGCGTAAATAATGGAACCGAGCTTGTCCTCCAAAAGCTGCCACGTTTCTATTTTGTTGAAGATTTTGAATAGGATAACTCTAAAGAACACCTCATTAAGTGATGACGGAAGCTCATCCTGGTAGATGACATGGCGTATTAGGTACTGGCTTACACGATCTGATGCGCGGTAGGCATTAGTAAATTTATATATCGAAAGAATTGGATCATCAGTCCAAGGCATCGGTGCTTTTTCTAGCTTTTTGAAAAAGATTTTTTGCCGTTCGGCAGCAAATCGCCAGTAAGTATTGAAGACAGCAGTCGGCTTGGCTGGAAGAATATGTGAAATGATCTCTGGTGCAGAACTTAGTTCGTTACCATACTCTCCAAATTCAAGAGTTAATTGTTTGTTTTGTTCGATTTCACTGACCTGTTTTCGACGTTTAGTTACCATGTTTTATTCCCTCGCCTGTCTGTTGAGCAGTTGTTATGTGCAACCCATTTTGAGCTGCATTTATGAGGGTAGTTAGGCTGTGATGTGACTTGGTAATAGTGTCCAGCTTGGCTACACCAACGAAGCAGTTCATACGCCCCAACGTCAATCCCATTTCATGAGCCATAAAATCACCCAGTCTACAAAGACCCAAGTAGTTACCGTAGGCTTTCTCATATATCTGTTGAGTAGCATAGAAAGCGTTGACCGTGAGGCTATTGCCCTGTGGTACAAAGCTCAGATGTTGAAGGCAAGGAAAAGGAAGTTGGGCACTGGAAACGTGATCTCGTGCAGGATCAAAGACCGATGCTTGGAACATACTTCTTCTAACTCCTGGTCGCGAGTTGTACTGAGAAATAATGTATTCAAGTTGGTTACCATTTTCAGGGCATGAACCAAATGCTATGAGCCTTTCAAAGTAAATACCACGTCGATTTTTTGAGCGAGCAAGAGCCTTAATTCTGGGTAAATTTTTGATATAGATATCAAATAACTTTTGGCGGTTATGTTTAGATACCCGCCAGTAAGCGGCAGGAAAGATCGTGTTTGCGACTGTTTCTACTTTTTGCTTGCTGTTAGCTAAGAGGCTATCGTCGAGTGCATCTCGAATTCCTTTATTTTCGTCTGGGACCCCATTAGTAAAACCTGTTAAGGTTATCAGCAGCGGTGAAATCTCCTTGCCAGGATTATGGATGATGTGTAGAAAAGCACGAGCCCAAGCACGGGAGAGGTTTGTTTCTTCAATTAAGGGAGGCACATTGTTATTCATCTTCGACCTCCTCAAGGTGACGATATTTACTTAGTCCAACAAACTGATAACGCGAAACGCGAACAAATACTGCCCATTTGTTGTTGGGGCAGTGGACGCGCACGATCCCAGGACGGTTAGCTCGAAAGAGGCGTCCTAAAGGAAGATCTGCTTGAACAGTAATAGTATTCTTTGTAGCCTCTGCCAAGGATGGCAGTAAAAGCTGACTTCCAACCTCGGCATCTATTGTAGGCAGTGACCACTGTGCATTAGCAACGATTAACGGGTCTGTTGATGAGCGCCCCAGAATTTCTTGTCGGATAGCTTTAGGAGTAGATTTAAGAAGCAAGGCCGCCTGCGAGCGACTCATCATTTTTAGAGCATAAGTCATGTGATCGATCAAAGTTTTGTAGCCAACACCAAAACTACAGGCGATTGTAAAAATTTGAACTGGCGTTGCTTCAGCAACATCCCATCCCCGCGAAACGAAGGCTTTCCGCACAGCTAAAATCGGCATGAGTAGGAAACCTGCAAAGGAGTCAACTAGAAACTCGTCTGGATTAAAAGTCTTAGGTTTGTCTGAGTCTTCTATGAGTTCATCAATCGTCGAACTATGCCCAAAAATGTGATGTCCAAGCTCATGGGCACAGGTAAAATTCCGCCTTGGAAGGGGTCTTAACGCTGAAAGCAGAATTTCTGGTTCCTCTCCTTTGAGGTATATTCCTTCCATACTGATGTCAACAAACCGGACTTTCACCTTCAGCTTGTCGCACAAGCCATAGATGCAAATAGGGCTATTAAGATCAAATCCTGCTTGATTCCGCACATCAATTGATTTAAGCATTGCTTGTTGAGCCAATACTTGCATCTGATTACTCACAGTTTGTCTCCCCCAGTTCGGATTGAGGCGGGTAATGCTATTGTTTATCACTGTTGGTTTCCCCCAGTTCGCATTGAGGCAAGTAGCGTTAGAAGCCGATCAAGGTCTTCTGGCTTAAGCTTCTGTAGTTCTCTGGCTGCAAGCTGGAGTTTGTTGTCATGGACATCAATTTTGTCCACGCCCTCACCGATTAACCACGACGCGCTGACATCAAAAATTTCAGCAAGCTGTGCAATCTCTTCAGCCGAAACACTTCTGTTAGCAGCTTCTATTTCTGAGATTGATGGTCTATGAAGACCCAGTATTTGTGCTACTTGAGCTTGAGAGAGCCCCGCCATCTTGCGAGCTTCACGAATGCGGGAAGCGATAATTGCTTTTTTTCCTATTGCTTCGGTCATCCTTGATTCTCCTTTCTGCTGACCATTTCGCAGACTACAGCCGCTGATTCACTAATATTAAGTGGACGCTTACCATCCTCTGAGAGAAAAATATTTTTATCATTAGGGATGTTTACGTCAAGCGCATCGGCCAACATACTGATTGCGACGGGCCAGAGCATACTGTCAAATCCTTCAAGGTTACTAAGCGGACACGTCGTTCCCACGATGCCGCTGCCGTCATATCCGCTATCGCTCTGGATGCCTTGAAGCACCTCTATCAGTTTCACCTCCACTTCGTTTGAGGTCATAGCCTGTACCTTTATATTACTAGGGGTAAGAATATCTTACCATAAATTTACAGAGTATCAACAATGGAGAACTTAACGGGGTTTCCATATCCTTGCAGGGAAGGAAACTTTCATAATTTACAGCTAAGTTTTGTACAGTACAGCTTGCTATTGGTAGTTTTGAGCTAAATATCAGGCTAGCATTGAGCTATAGTTTCACTTACGATAAATTTCAAAGCCGTCCATACTGATTGCTGGGTAATGTAGATTGATCGTGCCGTCCCAATCTCCAAATCAAAATAGGTAGCAAACCGTTTGAGATTCCCCGCAGCCATCCGGTACAGGTAATCCACCCCCTCAGCCGCCACCCGGACATTTACGCTCTCGCTCTGCAAGTTCAGTATCACCATCTCAGCACAAGATAGGTGATTTGTCAACTTTTCTGGTTTGGGTTTCAAAAGATCAGGAGCTTGCAACATTGGATATGGCAGCCTCGCACATCCCAGCCCCCCAAAATTATAGAACTCTGGGTCAGTTTCCAAACAACTGCCAAGCAAGATTTGTCCGGCTGCGGCATGATTTCCGCAATCCAAATACCACGCACCCCACCAAGATGGTCAGGCTTGTTGTAGGCGTAGCGAATCAACTTGGGGTCAAATTCCTGCACCAAAGCCGTCGCGTCCACTCCCCAAGCGATAGAGTATCCCAATGCTAGAGCCTGCACCTTGGGGAGTCCAATTTCCTTATCGCAGAAAGCTTGCCTGCTGATGTTGGCTTCTTCAACTAGATCGGGATCTGCGATCGCCTGCGGTAGGTTATGCTAACGCCATACTGCTGGGGCAACGCACGCTGCTCTTCACCTGTCTATATCCCCCTGATGCGTTAGCGAAGGTATCGGTTGGCGAAGCCTTTCCGCCTGGTGACAAAGAGGCTGGAAGCTAGACTGTATCGTGATTTTAGCCTTGAAAGCCCGAAGAGTGATGCTTGCACCGATAGCGATCGCCTCTCTAACTTCATCACTACCTCACCGCCAACTCTGTAAATTTACGCATATAAGGTGACCTGTATCCAAGCACGATATCAGACTTAGGCACTCCAGCTGCAATTAACTCATTAGCTATCCCTATCTCAGTTCCATCTCGTTGAATCCAAATTTTTCCCTCCCTAATCTCCAGGTGAATAACACATCCAAACACTCGTTTCTCTCCACGCCACCCGACATGAAACATCAGATAGCGATCGCGCTCAACATCGAAAGCAATTTGAGTCTCTACTTCGCAATCATCACTATCGCAATCACCCTGTTTTTCGACAATTGTTTTAATTAATTTTCTATATTTCTCTATCTCCATAATACAATTTCCTCTCTAATTGGATTAAATACAAGCAAGTTCAATTGCATCCGTGTCACTGACATTTGAGCCAAACGTCGAGTGAAAAATTCTTCATAAATATCTTCTGGAACTGCTAAATAAAGAACTCTATCTGGCTGTTGTTCTGCTAAAACTACTTTATAGTTCCAAGATTGACCGATGGCTGAGTGAAAATCAGTAATTAATGAAAGACCTAAAAAACTTTTAATTTCTACTGCTATTTTCTGCCCGGATCTTTCTGCTCCCAAGAGGTTATTTTCAGCCCCTAAATCAACATACAACCTGTCTTCATCTACTTTAAGATAAATAGGATCGTCAGTAATCGTCCACCCTTCCTTTTCCAGTGCTGAACGTACAACGGTATGAAAGATATCTTTTGCAGACATAGCTTGACGTGACGATTCTCCTCTATTCTTACTTATAACTCAGGCACGCTTCTTTTGGGTAAAATCTCAATAATCTTCTCAGCCAAAGCATTACCCAATTCACTGGGCCCCACCTTATGCAACCTCCCCCCATACACAGGCCCCTCACCCATCAGTCCTTCATCAGAAATACGCTATTGTTTTAGCATTTCATTCACCCGACGTGGGACAGCACAGCGGATATGCGATCGCTTAGAATTCCCATTCTTGATGAATTGATGGCACAAAATCTCGAAGAAATATTTGGTTTTGTGCCAGACAGGATAAGGCTTTTAGAATTTTTTCACGAGATATCTCAATAAACCTTACCCGAACTCATAGCCCCGTCATCCCTCTGTCCCCTCCACCTCCATCAACTCTGTGACAATCCGTGAAATCAGTGGTTCATTCCACCTCCCCATCCCTAATTCTGAGAAGTCGGATTCGGCTTATTCATCTCCTCCATAATAATTTCTTGATTAATCAACGCCTGAGAATGAGTCGGATTGAGTTCCAACGCTTTTTGGGTCGCTGCTAAAGCATCCCCATATTCTTCTAAAAATCTCAGGGCGATGCCTTTCCCCGCCCAAAAATCAGCATTTTCAGCATTAATTTGGATAGCACGTTCGTAAGTTGTAACCGCCTCCCCATAGCGGCGCAATGCCATTAGTCCGAGGGCGCGATTGTAGAGGGCGGGGGCGGATTCGGGGGTCATTCCTAGGGCGCTGTCAGCGGAGGCGACTGCTTCGGTATAGCGTTCTAAGCGATAGAGGACCGCACTCTGATTTACCCAAATATCCGCCATTGTGGGCCGATCGCCTACGTTGGCATCCCCTCTCAAAGCGCGATTGTACGCATCCACGGCTTCGTCATATCGGCCTAATCCGGTGAGAATTCGCCCTTGATTAAACCAAGCTAAGGATGACCCCGGGGCGACTGCGATCGCCCGTTCCGTAGCGGCTAAGGCTTCTTGTTCTCGGTTCAAATGCCACAGGGGGACGCTGCGATTACTCCAAGCATCGGCTAACTGGGGATTAAGCCCGATCGCCTTATTAGAAGCAGCCAGGGATTCTTCATAGTTTTCCAGTCCCGTAAGCGCATTGGCTAACTGTACCCAGGCATAAGCCGGTCCCAAGTCTCCCCAGTTGCCATCTCCCTCCTGCAGTGCCATTTCACAAGCCGCTTTTGCCGGTTCATAGCTGCCTAATCGGTTCAAGTTGGCGCATTGATGCAGCAAGGTAAAGGAAGATTGGGGATTGATTTTAACTGCCCATTGGAAGGAGAGTTGCGCTTCGGGGTGTCTACCAAGGATGCCGAGGATAATCCCTTGTTCCGTCCAGGATGCAGCATCATTGGGTTCCAATCCCAAGGCGCGATCGTAGGCAGCTAAGGCTTCGTCATAGCGTCTTTGGGATTTGAGCAGTCTGGCTTTGTTCGCCCACGCAACAGCGGGGTTGAGGGTGCCCCAATTTTGATTGACTTGCAAGGCGCGATCGCAAGCCGTCAGTGCTTCTGCACCTTGTCCCAATTCCGAGAGAATGGCGCATCGTCTTGCCAAGGCGATGGAATAATTGGGATTAATTTTAATTGCCCATTCGTAAGAAGTGAGGGCTTCTTCGATTTGACCCGAACGACTTAAGGCGACTCCGCGATGATACCAGGCGACCGCAGGGGATTGGGTTTCCCAGTTGTTATCCATGCGTAAGGCAGTGTCACAGGAGGCGATCGCTTCTTCATATTGACTGAGTTCGACTGCCCCGGAACAGCGTTTTGTGAGTAATAGGGAATTGTTGGGGTCGCGTTCAATGGCTTGGTTGTAGGAGGCGACGGCTTCGGCATACTGGGTTAAGGCAAATAAGGCATCCCCGCGATCGCTCCAAACGATGGGGTCATTGGTATTTAAGGCGATCGCAGCATCACAGGCGGCCACTGCCTCCTCATATTGCCCTTGTTCCAGGAAGGTTCGACATAACCCCGCCCAATGGGAAAAATCCTCTAACCCCTCCTGTGCCAATACCCGAGAGTTGCCGCTTCCCACCCCCATTCCAGCCATCATCAATAGAACAGATATCCCGATTTTTACTGAATTGCTTCCGGTTTTTACAAGCTGTTTATTCATATAATTTTCCTGCTACTGTCATCATTGGTTTGGATTAGTTTCTTCCGAATTACAGCGATTTTCGATGCCATTGGGCATAATCGCGTTACACAAATAAACCTGACTCAAATTCACCCCTTCTAAATTTGCGCCGGTCAAATTTGCCCCGCCCAGATTTGCTCCGGTTAAATTCGCTCCACTTAAATTGGCATTTTGCAGGTTCGCCCCAAATAAATGGGCGGTTTCCAGATTGGCTAGACTTAAATCCGCTCCTTGCAAATTGGCATTTGCCAATCTCGCCCCTTTTAAGTTAATCCCACTTAAATTGGCTTCCACCAGATTTGCCTCGGTTAAATCTTGGTTTTCCGCCCCCTGTTTGATTAAGTCTAAAATAAACAGCCATCGACTTTCTATAGCTGTTTCTTCATTAATTAAAATATTTCGCAGATTGGCATTTCCTAAATTTGCCCCCAATAGGTTAACGTTGCCTAAATCAGATTGTTCTAAATTGGCTGCAAATAGATTACTATCTTGCAGATTTGCTCCCTTGAAATTGGCATGACTCAAATCCGCCCGAGTTAAATCAGTTCCCAATAAAATGCTATGACGTAAATCCGCCCGATGCAGATTTGCCCCGACGAGATTGGCTGAAGTTAAATCCGTATAATGGAGATAAGATTGGCTTAAATTGACTCCCGTCAGATTCGCCCGTTCTAAGTTAGACATAAATAAGGAAGTGCCCTCCAAGTTGGCTCCCTCCAAATTGATGCCGGTTAAGTTCATCGCTTCGAGATTTGCGCCGGATAAGTCACTTCCGGCAAGGGTTTGACCGGCTAAGGGTTGATTGACAACGGTCCAAATAAACTGCCATTTACTATCGAGAATTGTTTCACCATTCAGGATAGTCCCTTTGAGATTGGTTCTAAATAGTTTGGCTTCTTCTAAGTTTGTACTACTGAGATTTGCGCTTTCTAGGTTGGCATTTTCTAAGTTAACTCGTTTTAAATTAGCGCCGGATAAGTTGGCATTTTTTAAATTAGCATTTTTTAAATTGGCTTTTTCTAAATTAGCCAGAGGGAGAGTGGCGTCTTGTAAATCGGCATTTTCTAAATTAGCTTCTTTTAAATTGGCAAGTTCTAAATTAGCGGAATTGAGATTAGCGCCTAAGAGTTCGGCCTTTTCTAAATTTGCTTGATGGAGGTTGGCTCTAAATAAGGTTGCCCCGTTGAATATAGCTTTTTCTAAGTGGGCTTGTTCCAGGGTGGCGCTGCCGAGGGTGGCATTGCTTAAATCCGCTTGGAACATTCGCGATCGCGAGAAGTTCGCCCCATCCAGTTTCGCGCCTCTAAGATTCGCCAATCTCAAATTAGAGTCGGACATATCTGCACCTTGGAGTTGCGCCCCCATCAGGTTTGCTTCTTGGAGGTTACAGCGCGTACATTGACCCGTTTCTTCCAATTTAGCGACATCCGAACCCCGGGCAGCAAAGACAGGATTCGGGAGAAAAATTAGGCAAAATAAGGACCAATGACCAATGACCAACAACCAATAACAAAAAATGGGAATAGGCAGGCGGGATTTTTTCATATTCATCAACCTGTTTTTCTGGGGGCAAACATAACTATTACGCTCAAGCGAGATATTTTTTCAACAAACAACAAATGACCAATGACAACTTTAATTAAATTGAGGAGGCAGTTCTGCTGGCGCAAGGGGTTGAGTCTCAAAAAACTGGGGACCCGGTTCTTTGACGGGTTCCTCTGCTGCATCCGGCGCACCATCGGGGGTGTCCCCTGGGGCTGCTGGATCGACACCACCGGGGAGATTTGCCCCAGGAACAGGGAGTTCTACGGGGGGTGGACCCACAGCATCGCCGCCCGGGGTGGGGGGTGCGGGAATGACCAAGGCTGCGTCTGGAGTCCCGGGTGCGGGGGCAGCAGCAGGGTCACCCTCTGCGCCAGTCATGGCCCCGGGAGTGGGCACCATTGCCGGGGCTTGCTCGACTGCCGGGGGTGGCGGAACCTCCACGGGTTCTGGGGGCGGCGGGGGTGCTAAAGTTTCGATAATCACCGATCGCTGTTGTTGGTTGCCCTCTTCATCAGTGACTTGCAAAGTAATCATTTCACTGCCCGGTTGTTGACTCACGGGATAGGGCATTCTCCCTTCCCGGGGCACGGTTCCTGGGGCTGGTAGCAGTTCAACTTTCATGCCATTTCCCCCCTCTACCTTCCAGGAAATCATTAGCGAATTTTGTTGGGGATTGGCTTGTCGCACCAATTTCGGGGGTGCGGGTTGTCCATTAAAGGTAAATTCCACAATCCGGCTGGGAATCTTTTGCGCCAGAATTTTAATCGTATTGGTTCTACGGGTTTCTAATGGTTCCGGTTGTCCTTTTTTGGGGACAACGGTTAAGTGAAAAATATAGTCCCCGGGTTGAATAGCATCGGTGGGAACATTGGTACAAATCACTTGGCGACTGGCGGGGTTCTCTCCACAAAATCCCCGCAACTCTTCGGGAATTCCCTCGGCAAAGTTATAGCGTTTTTCTACACTTTTAACCGTGCCATCAGGACCCAACCCGAGTAATCTAATCTCTTGAATCTGATCCGGATGAGAAAGCGCCCAATTTAACAAAATCCGATTACCCTGGGTGGAGGAGGTTGAGGGTGCCGTCGGGGTCGATTCCGTGGGGTTAGCGGGGGTATTCGGGGTCAACAGGCGCTCTTGGTAGACAGGTTGAGTGGAGGCAAATTCCTCAATTTTGGGCTGAGGAACGGGTAAAATCCGAATGGGATTGGTGCGGATGGTTTGGGTTTCTGCCTTGGAATTAATGGGAATAGCGGTTAGTTCAAATACATAATCCCCTGCCTCTCTGGCGTCAGTCCAGACATTGCGACAAATCAGTTGTTCCCCTTGGGTACAAAACCGATCCAAAGCATTGGGCAATCCCGGGATAAACTCGTAAATAAACGGTCCACTCCGGACTAGTCCATCGGGAGAAAACCCAACTACAGTTACGGTTTTGAGGTGAGTGGGATTGGAAATGGTCCAATTGAGGCGGATTGCTTCATTATTCAGTTCTTGATAAGAATTGCTTTCTGGGGAAAATTGCATGACTTGTGCTCGCACGGGGGGGCGAGTTAACAGCCACCAAATCAGAAAAATCAGGGCGGCCACACTGGCTGACATTAGGATGACGATGGGTAAGAATTGCCACCAGGGACGGGGTTCCCAGAATAAGGAGGCTTGAAAGCGATCGTTAATTAAAGGGTATTGTTGGAGGTCTTCGAGTTCAATGCTGAAATTAATCATCCGCCCGAAGAAAGGCCGCCATCCCTTGGTGGGTTTGACCGAAACCCCGACAGTAACGGAGGTTCCGGGTAAGAGTCGCACCATTGGGGGGGCGATCGTATAAGTACAGATGTCCTCTTCATCGGTACTTTTGGCATGGATGGCAATCTCGCGGATGACATTGCCCTGATTGGATAATTTCAGTTCAAACAGTCCTGCCTCGCGCTTAATTTTGGCGACGAGGGAAAGCAGTTCGACGGTGACCAGATGCAAGGAAGCAATCTGGAGGTAAACGACATCCAACAGGGCGAGGTCCGGATTGTTGGCGGAGTAAACTCGAATCGTGGGGGCATATACTCCGGCCCAAGTATCGGGAGGCGGGCTGATAAACAGCAAGATTTGACCGATATCCCCGGGATTGAGTTCGAGCCCATCCGAGGCGATCGCCATGCCAGCTTGTTGGAACCCTTCGGGATAGATAATGGTAAACCACCGAGATTCCAGGTCTGGACAGGTCAGAAAAAAGCGGTCTACCCGGTCCGAACGGTTATGAACGGTGACCTGGAGTTCCAGGGGTTGTCCCGGTTGCAGGAGGGCGGGGGAAACCGAACTGGTGGGGGGTTGGAGGGTAAAGGTGGGGTCACTGACGGTCCGCGCTTCCTGAACGAAAGGCATGACCTGCAATCGCACCTTCTGGTCAATGGGGGTTTCTTCGGGGTAATGTTGGGGCGCATCAATGACCAGGGTATAGTCGTAGGTGCCGGGGATGGCATCCACGGGAATCTGCACCCGAAACACAACTTCACTCGCTTGTCCCGGACTTAAGGCGAGTCGTTCCCGAGGGCAAACAAACCACTGATGAACGGGTTGGGAGGTTTCAGCGATGAACAGATCAATGATGGCGCTGACGGACCCTTGATTGGTGATGGTTGCCGTCAGTTCTAATACCTCCCCTGCTGTAACTAAGGCAACGCCTGCGGGATTGAGGATAATCCCAATCGGACGAATCATGGGCCGATCGCTGTTATTCTCTTCAAATCCATTAACTATCTGCCCCGAGTTGGGACTATAACCCTGCATTACCATTCATTCTGCTCCTTGAATGACAAACCACCCACCACAAATGACAAATGACAAATCCCCCCTTAAGGCAAATCACACCCCAAGTTCGGTAATCGAGGGTGCGATTCGACCCGGACCTCTTGTTGATCATCGCTACCGGCAGCAATCAGTAGATGGTTATCCACCTCTTTAATATCGACACTATTAAAGTTTTTATTTTTAGCCCGCAGAATTTGCTCTCCCTGGGGCCCGGCCCGACTGCCATCCATGTTAAGCGGCCATAACATCACCCGGCCATCATCGCCACCACTGACGAGGTAACAGCCATCTTCACTCAACGCCACCGATCGCACAGGTTGGCCATTGTGACCGTCATTCCATTGTTCGATTCTTTGGCAATCTGCGCCCCCATTCAAACAGGGCTGCATATTCCATAAAGTAATATACCCTTGGTTATCGGCAGTAGCGACCAGGTTGGGATTGAACTCGGCGGTATCCAGACTGTTAATATACGCATCTTTTCCCCCTTCCCGGTACGGCACAACCGCTTCGGTATTCTCTTGCCAATTCCACAGCACAAACTGATTCAACTGTCCCGCCACAGCTAAGGTGCGATCGTCATTCCCCACCAATTTCAGGGCATAAACAGCAAAGTTAAATTGTTTGAGATTCGGAGTCATGACTTCCGAGTTGGAATTCACCCGTTCCCCGTTTCTCAGGTCCCATTGTAAGACAGACCCACTCCCATGACCGCTAAATAAGAAGCGAGAATCTTGGGTAAATTCTAAGGCAAACACCCGGTCATCTCTTTGATAAACAAAGGACTGCAACGGGTCCGGTCGGTTCTCGGTCAAATTCCAAAAGTGAATTTCCCCATTTTCTAACCCAGTTGCTACCCAATTATTGTTAACGGGGCGATACTGCACGACTCGCACTGCTTTTTCGGCAAGTAAGTCGGTACATCCAGGAGATTGGCAATTGCCTCGGTTTTGAAAGGGATGAGTCAGCCATTGCCAGAGTCGATTCCCTTTGTGAGGGAATTTCCGCATTTCTTGATTAATGATGGGATTAAAAAATCCGCTGATGTTCCATTCGATGATGGTTTGGTCATTGGAACCGCTAATCAGTCTTTCCCCCACCCCATTAAATTGCACCGTGTTGACGGGTTCATTATGTCCAATAAAGGGATTTTTAGCATTCAGCCAGGATAACCACCAGAGGAGATAGAGGAGGAAGAGTCCGCCTAAGAGTTGTAACCCTAGGGGGAGGACGGGTTTAACGACTAATTCTAGGGTGTGACCTTCATTGCGGACATCCACCCGGCGATCGGACCAAATCCCGGTCAATTCTAGGAGGAGTTTCCGATTTCTGCCAAACCAGGGCCGCTTTTTGCTGGCAGTTAACAGGAATTCAACGGTTTCTTCCGGGGCGATCGCACTCGCTTCGGGGATGAGGGTCAAGTCGCATTCCGGGGAATTTTCTCCGGCGAGTTCTACGGTTGTTTCTTGGGGTAAATTGCTGGCATTTTTGGCTTCCAGGCTGTAGGTAACCGGGTGAGACTGCCAAAATTTCCAGTGGAGTTTACTAGGAATAGCACGCTGTTTGGGCGTAGCGGTAAACTCGACAAACCCCATTGGCATCACCTCTAGGGTCCCGGAAACCTGAGAGGCAGGGCCATTATTATGGGTGGCTTCAATAATGAAGGGGTAGGCTTGACTAGGGGCAGTGGCACCAAAGGGGGCTTGATAGGTAAAGCTGGTTTCGATGGATTTACCTGGCGGCACTTGTAATCGGCGTTCCCCGGAAAGAGGCAGCCATCTAGGGTCGATCGCCACTTCCGTGAGGAGGGCATTGCTGAGGAGTTGTCCGGGGTTGTAAACCCTCACCGGCACTTCGATGCGACTCCCGGGAGAGATTTGAAATTGTTTGACCGGGAGTTCCAGTTGCAAGGCAATTAATCCGGTCCCCCGTTCCACCACCAACCGGAGAATTTCCCGCGTTTCATCCGGCAGTTCCATGGAGAAAACACGCACCCGCAAGTTCATCATGCCCACAAATCCCGGGACTGGGGTATCGAGAATGGCGACATGAAACTGGGTGGCGGCACCGTTCGGTGTTTTGCTGCTGGCGGTGGGGGAGATGCTGTACCAGTCGCCATTGCGATCGGCAGCAGCACCAGCGGCGACGAGTTCGACTTGAAAGCTGGCAAAGCGATCGCTGCCATTCACCACCGTGACTTCAAACGATGCCGGGACTCCTCCCGGTTGGAAATGGAGTTCTTTCGTTGAGACAATTGTATTAATTACTGTAGTTGCCATACGATTGCTCTTGTCTCTTAATAATATAAATTACAAGCCAAATAAGGTTGACATTCGATTGCGGATCCAACCTAAAGGATTTTGATTGAACCCCTCTTCATCATCTAACAACCCCATTTTTTGAAGCAGTTCTTTTCTCGATTCTAGTTCGGCTTTGTGTTCGTGCAAGGCTTGGGCAATTTGTTCGGCCAAATCTTTATAATTCCTTAAGAGTTTTTGCAACCCTTCGCGATCAAGCACAAATAAAACCGTATCTTCTCGGGTCCGAACCGTGGCCGTTCGGGGAATTCCCAGGAGTAAGGAGAGTTCGCCAAAAAAGGTGCCCACACCCAAATTGGTGAGAAATTTATCAATTTTTTCCACAAAAATTTCCACCGACCCTTCCAGAATAATATAAAACGCATCTCCCGGCTCATCTTCCCGACAAACATATTCCCCGGGATACAAAATTTTTCGATACCCCATCTCAATCAGTCGCTGAATTTCGGCATCGCTGAAACTTTGAAAATAAGAGACTTTTTGTAACAATTCAGCAATATCTATCTTTTTAAATTCTTCGGCTTTGCTACGAGTCCGCTTAGATTTAATCAGCAACTGTTGAAAGTAACTGCTGTCGCTCATTTGAGTTAACAGCATGGCTTTTTTGGCTTTATCCGTCTCAGTTTGAAGCAAGCTCAATTGGTCTTTAAACCCTTGCTCACGCGCATAGATTTTGTTCGCCATATCTTGAAAGATTCGCGCCAACTGACCCACTTCATCGGAACGGTTGGTGACCTCGGTTAAACTATTGGGGTCAAAATTGCCGAGTTCGATATCATGGGCGGTGGCACTGAGGCGTAAAATGGGCTGAATTAACCACTTGGCGATCGCAATTCCCAGCAGCGTCGCCACAACCAATGCCACTAATGACAGGACAACCGTATTCCGCGTATTTTGATAGATATACCCCATGAAATCTGCTTCAGGGACGATCACCACAATTAACCAGTCCAGACCTCGATCATCCTGGAGTGAATTGACTGCTACCCATTGCATTTTCCCATCCAGAGAAAATTTAAAATTCTGGGGAGTCTGAATGGTATCGAGACTATTAAACTGTGCTAATAATTCCCGTGCAGTACCTTGAATCGTCGGATTGATACTCTCAATCGCCCAGAGTCGGTTAGAATTGCCCAATGGGTCCGTGGGTCTATTTTCCCCCTCCACGAACAGATTTTCTTCTACCGAACTCGCCACAATTGCACCGGACCGTTCTACAATAAAAGCGGCTCCTGCCGGAGAAATTTCTAAATTGCTTAAAAAATTACTGAGTTCATCCAGGAAAATATCAATTCCAAATACCCCTTGTAGAGTTTCCCCAGGTCCATAGACTGGCGCAGCTGCGGCAATCCCCAAGACTGAATCTTGGAAGGCAAAACGGTAAATCGGACTCCAGGTCATCTCCCCAGTCGCCTGCGCTTTTCTATACCAAGGTCGCACGCGCGGATCAAACTCCCCAACGCTAATTTCGCCAAGTCGATTCCCCTGATCATCCAGTTGATAGGTTTTGCTGACGGGACCCGTTTCTTGTTCACGAATTCGCAGCACTGGGTTTCTATCATTGGTTAAGTTAATTTCAATAAACTCTCCCGATTCATTTCCATAAAAAGAAGAACTAATGGAATCATTCCAACGGATTTGATGCCACAAATACCGTTCTATTTGTTGTAAATTGTTGACATTTAAGTTACCACTGCGAATCGCGGCTAAAGTCAATTCATGCAAAACCTGGGGTTGTTCCATATAGGCGGCAACTTCCGACTCGATGCGATCGCTGACTTCTTGCCCTAACTTGCGAACTAGCATCTCAACGGACTGCTGTCCACTGCGAAAGGAGAGCCATCCGGTCACTCCGACGGCGATGAAAATTGGAAAAACGATTAGAGCGGGTAGAACTTTGCGGATTGAAACCATCTTTTTTCCCCATGATATGGCTTAAAATTAGACCGGGTTCTGACAGGCTACAGGAACGGGAATATCAAATCGAATCGGGGACTTGGATCGGTTGAAATTCTTTGGCTTTTTGTAATTGAGTGAGTTTCCGACGGGTGCGGGCATAATGTAAAATATTAATGCCCATTTCCTGTGCCGTCCGAATCGTTTCTCTCCCTAATGAGAGCTTTTCATCTAATCCCCAAGCAACGGATAAATTGCCGATAAAAATTATAATTCCTCCCCCAGTTAAGATTTTTAAGGCTTGTCCGTTGACAGTGGGTAAAGCTGAAAATAGAAACGGTTGAGTTCTCAGGGGGTGATTCCGGCTGAGGGTATCTAAGTCTTCTAAAGGGATGCCTAAATCTCGGGCAAACTTTTTAAAGGCGGAAGATAGGGTATTAATTTCTTCGCTCAATGAGCTTTTAACGGAAATTAATTCTTCTTCTAAGGATTTTTTAATTTCTAGGTGATTTGCCAGTTGTTCATTCCGAGAAGCAGCAGCGGTTTTACCCGGGGTTTCGTTAGATTCAGTGGGAAGATTTAAACTCATCTCCAACCGGGCGATCGCCTCTTGTAACTGATGCTGTAATCCAATCAATTCCTCCACTTTTGTCCCCTTAATCGATGCCTCCACCAACAACACCCCGCCCATTTCTATATACTGCCGTAAAATATCAAATTCCCCCGGACTGAGGGCGAGAGAGGGTTGGGTTTTAAAATACAAGACATCGTAGGTGATTAAATCATTAATTTCTGAGGGTGAATTTAAAGTAAACTGCCCGATTTCATTGAACCCTTGCCAGACTGGATAAAGACCGGCGATCGCCTGACTCAAATAGGCCAAATTAGCATAAATCTCAGCATCTTCTGGCGTATTTTTAACCACCTGTGCCAACCGGACAACCGCCTGAGTGCGAGCATTCGCTTGGGGTCGATACCGCAGATCTAAATTATTAACCCCAGGAAACCAAGCATCTAAAGCGGTAGAAAGTTCCACCTCTCCCGGTTGCAGCAAAATTCGACAAAGTTCAACCTCCCACTCTGCCGGAGGGCTATTCTTTTCATCAATTCTAAAAGATTCGGTGACAATATCTCCATTCCCATTTTCCTCTCGCACCAATCCATCCGGGTCTACATAACTAACCACCAGATAAACCATCAGCGGTTTTCCCATCAGCGCCGCCGAAGTAATCCGAAAATCAATCGGTTCAGGAATCACAATCAAATTCCCAAATAAATCAATCGCAATTCCAGGCTGAACTTGCACCCATCGTTTGTCCCGATATTGGGAGGGAATCTCATTGGGGGGTTCAATTAACCGCACCCCCATATCACTGACAATTCCCGGTTGATTCAAGGATTGGAAATGAGCATTTTGGCGATGGCGGTGGTAGTCATGAGCCAAACGCCATCGTTCGGCATCAATTAACAATCCATCGCTCACGTGCAGCCGATTTAAAGGTTTGATATTGGGAGGGAGCCAAGGTAGTGTCATGTTAGGAATTTACCAAGTAGGGGTCGTTGGTCATTGGTCATTTGGGGATTGTCATTGGTCATTGGTCATTTGGGGGTTGTCACTGGTCATTGGTCATTTGGGGGGTTGTCACTGGTCATTGGTCATTGGTGGTTTGCTTTTCCTAATTATTCCTCGCTACCAAGGACAAATGACCAATGACAAATGACCGAGGACAAATGACCAAGGACAAATGACTACTCAATGCGCTGGATAGTATTAACGGGATTGATATAAAGGTCGTAAGTACAAAACGCTGGTTTTTCTTGTTCGATAATTTTACGAACTAAGCTTTCATCAATTTGGTTGGGATAGTCCGGTCGCAGTTTTACAATAAAATGATAAGGTTGTCCACCTCCGATGCTGGTATCTTCTCCTAAACGACTTTTTCCGAGCACTAATCCCTGGGTAAAAACCTCTTGAATACTGATATGTTTTTCATCTTCCGGAAGATGTTCATCCAGGGGCAAATTGGTATAAAGATAGAGATAAAAACGCAATCCCCGACGAGTGCCGCGCCAACGGTAGAGTTCGATCGCATAGCGGATCAGATAGCGTTGCTGTGCCAGACTCAGGTGCGGGTCGATTTCCCAACCCACCCAGTACGCCAAAAAGGGTAAGAGACTTTCTGGAGCCATCAGGGGGTCAAGATAGGCCCAGATTGCATCCATCGCCTGAACCGTAGGCTCAAAACTCTGCTCAAAAATCGAGAGCAATCGACCGATAAAGTCTACTTCCTGGTAGAGTTCCGGTAAAAATTCCAGGTAGAGACTCCGGGGACGCAGGTAGAGGCTGAAGGCAGCGGAATCCCGATGTTCTCCGGTGCGATTTTCCTCGGTGCAAACGACGCTCAAGCGGCCCTGAAAATCCAAAAGCGCCGGATTGGCACTGATCACCTCTGGGCTCTCGAAGAAATTGGGGGGAACGTTGAAGTAGAGGACCGCTTCCATCGTGCCTCCCGGAGGCAGTTCGTGCCCTTCGGTTCCCAACTGGCACCACTCTGGAGGGAAATTGCCCGTCACTGCGGCATTGACTTCCAGGGTGCGAAGGCCGATGTTTTCCAGTTTGACCAGGATTTCGCTGGGTTCTCCTGGATGTAACACGAGGTCACAGCGATTTCTGGGGTGTGGCAAGGTATTCCTGGCGTTGACAGTGGCCGATCGCACCCCTTCGGCAATCTCTAATGCTTCATGCCACCGTCCCACCGGCTCAGTCGGTGCTTCTGGCACTTGCATGGGTACCAATTGCAGTTTTAATGGGAGGAGGTCACGGGCTTGAGTCATGAGGGTTAAACCACGGATTGCACGGATTTTCAAAGGAGTTTAGATAACACTGATGGTGTGACCCGATCGCAGGGTATCATTGCGCCAGGAACAGACTAAACCCAAGGGACCGGGGTTGATTACCGGATCGGGGGGGAGACGTCGCACCCAAACCCCGTTACGCAGACGCAGTTCAAAGAGTTGGACGGACCCGAGGTAGAGGACCCCGGGAATGTTTTGCAGGATGGTGACGATATCTGAAGGATACACCGGACGGCCAAAGGGCCAGCCGGTCCCGTCGGGTCCTCCGGTGAGGGGGTTGAGAAAGCGATAGAGCGCCACTTGCATGGAAAAGATGATTTGCTGTTGGGCGCTAGGGTTTTTATATTCGGGTTTGAGGGCCACTTCTGTTTGCACGGATACCCCCATATAGTTGGGTTGGTTGCATTGGACCTGGACTCCCAGTAAACGGCGATCGTCCAGATAGGTCAAGACGCGATTGATCAGGACTGGGGAGAGGTTGAACAAGTCCGGGTCAATGCCTTCGCCGCGTTCAATGCTCAGGGTGTCGGGTTTGGGAACCAGCAGCATCCGCACGGTTCCCGCTTCGGATTTGTGGGTGGGGGGTAAGCACAGAGTCCGGGCGACTGCGCCTTGTCCCGCTTCTAAGGTGAGGGTTTCAAAGTCTTCTACCGTGACAGCCCGATCGCGGGTGCGGAGCATTCGCGGGGCGCGGATCACCGCTTCATCCAGGGATTCGCTATCGGCCCCCCCTCGTCCCGGCAGATGGTTGATCACCGCCGCAACATAAGGCACCGCTGATTTGACAATTTGAATGGTTCCAGCTTGAACGTTGCCTCGCAGTCCCCCTCCCGTTCGGTAACTGACAATTTGAAGATTTGCCCCTCGGGGAGGGACTGCTCCATATTGTCGTTCCATAGACTCAATTCCCGTCGCCGTCATCGGTTGAAAGGCATTGCGATCGCCCGGGCGACCATTGGCTAAAGTCAAGGAACCCTGACGCGCACCTTGTTCCGATGCCCGCCAAGCCATTTTTTCCCGCAGTTGCGTCGGTTCGCGGATCAGGGGTCCGAATTGGACTTTTCCCGTGAGGGAATCCAGGGTATAGTGCAGGTCTTCCGGCCCCGAAGTGGAAAAATCATTGACTTCTTGCCAGATTTGGGGTAAACCGCCGATGGGGGTGACGAGGATATATTCATCTTCTCGTCGGGGTAGGACCGGCACCCCTTGTAACTGAAAGGTTTGTCCGGGATTGCCGTCGCTTTCCCCGAGGATTTCATTGCGAATTAGGGTACTTTGAGAAGCGGTGACACTGCCGCCAATGGAACGGGCGTTCAACCCGACAATTCGGGGCGATCGCGTATATCCGGCTTGATAGGTCGCCGGTTGGGTATAAACGCAGCGGATCCACCGACCTTGGTAGGTAAAAAAGTGCGTCACCGGCCAAGTTTTCGGCATATGCAGCACCACATCAACCCCGGAGAGGGGGTCGCCCCCTTGGCGGACAATTTCGCTAAAACTGAATCCTTGGGTCTTATCATCCGATTCATGGAGGAGGATAGGTTGCCACTTTTCCCCATTCCACCCTTCCCATCGCCTCGGAGGCATATCGGGGTTAATGCCGGTGGAGGTGGCAGCTTCCCCTTTCAAGGTGAGGGCGATGACATTTCCTTCGATCAGCGCTTCTGAATCAAAGACCAGGTAAAAGCAATTGCCCGGTTCTGGAGTATCGTCAAAAAAGGGCAACTCTAACCCTTGCCATTCCCCAGTTCGTTCCATCCGCCAAGACCCGATGAAGCGATCGCGCAAAATCTGGGGTTCCTGTTCCGCAGAGGGGGCCGTTAACAAATGCCGAATCCGAGGTTTACCCACTGCCACCGGCGCATCCGTACTAAATACAATCGCCTCTTCCTCTTCCGTCCGCACCGTCGCCACCTCCGTCCCTGCCGGAATGGTGTAATTTTCCGGTAAGGAGGCACTCATATAGAATGTCACCTCAGTTTTAGCCGGAGTCGGTGGACGTAAGCGCACCCCCAACAACTCTAAAAACGTCACATAATTGCGACGCGGCACCTGATTAAACCGGGCTAACATTTGGTCCGTCATCCAAGCGAACAGTTCCACCAAAGTCACCCCAGGGTCACTGGGGTTATAATTCGTCCATTCCGGACAGTAGCGCGGAATCCGCAGCAGGCACTCATCCACCAAATCCTGAAACTTGCGATCGTCTAAATCTGATTTAGGTAAATTCGGTAAAAAATCAAAATCCAT

Protein sequences of DBSCAN-SWA_1

>NC_019693|1270355:1317615|1314258_1315344_-|WP_015147454.1|tail|DBSCAN-SWA
MTQARDLLPLKLQLVPMQVPEAPTEPVGRWHEALEIAEGVRSATVNARNTLPHPRNRCDLVLHPGEPSEILVKLENIGLRTLEVNAAVTGNFPPEWCQLGTEGHELPPGGTMEAVLYFNVPPNFFESPEVISANPALLDFQGRLSVVCTEENRTGEHRDSAAFSLYLRPRSLYLEFLPELYQEVDFIGRLLSIFEQSFEPTVQAMDAIWAYLDPLMAPESLLPFLAYWVGWEIDPHLSLAQQRYLIRYAIELYRWRGTRRGLRFYLYLYTNLPLDEHLPEDEKHISIQEVFTQGLVLGKSRLGEDTSIGGGQPYHFIVKLRPDYPNQIDESLVRKIIEQEKPAFCTYDLYINPVNTIQRIE
>NC_019693|1270355:1317615|1293007_1293997_+|WP_015147437.1|DBSCAN-SWA
MQPSPRIQLTHYYSEEIGVSLELPEHWQEGESNGERVSYSCASDGPYHPQLLIQRVPLSGERVSDGCDRLAEELLQLYPSPLEMGDRHSLTVDNFPARLDIFSFYDPEFNIQVTHYQVCIQLPDALCSVVGIVEGQSAESLLPVFEQAVGSIRFIGMGMGRTALMSDPSTRISYFNPGLGISILIPASWSVQELQENQFQAIGPSVPEFDGYHPRISCTRTIPTNQTPAGLEEAIRKSETTHRLLYSDYEILKQERFSLGPYPAYLRQMQWSYQGTDIYLVNVQGLIWTPSSAYVFKAETLKQYESRDVPIFEAIVKSTRIIPASCPDV
>NC_019693|1270355:1317615|1272184_1273909_-|WP_015147422.1|tail|DBSCAN-SWA
MPLDYFAPGVYVEEVDRGSRPIEGVSLSVPGFIGFTEDVRGDAEVFQPMMVTTWDQYLEYFGKPGSDGFTDFDAYLPFAVYGWFLNGGGRCWVSSIGTKLPGSEAPPPEKTATKLLTSSGRPALLFNLKGAAGETEDGEAPALPAATGRVTVKVESSTPKPPEDEDAEPPIDDGQFFKVTVKRGDTVVETHDNLTMKEDVEADLGSYVLTALQESEAIDVSIPEGLGAISPLSKRPLNGTYEVAPPPPFIQDPDRLPRELQGKRDDRTGVQGIFEIDDVAMIACPDLMRVYQEGLMDIDQVHGVMEMMVSMCENSAPSPPFRMVVLDPPPIKPGKNENRAVAPEQQKPQDVAKWLREGFNRRSMFAALYYPWIKVANPRNGGRPIAIPPCGHMMGVWCRTDETRGLFKAPANDTPRGVIGLAYETNFREQELLNPLGINCIRNFSNYNRGIKIWGARTLAEPDNIQWRYIPVRRMMSYIEKSIEIGTQWVVFEPNDSTLWGRVTRTVSSFLEGLWRQGALVGGTASESFFVKCDGELNTADTMMMGRLYIEVGVAPVRPAEFVIFRISQWAPGQ
>NC_019693|1270355:1317615|1287456_1289769_+|WP_015147433.1|DBSCAN-SWA
MATGRQIQKKGQSNATPTPATGMFKPRPFAMPAEPEAATAPELQTKTEPGQVGGSRLSRIDVSAPPPIQPKLAIGAPDDKYEQEADTIARKVVKQISTPTPPDANGGGDSVQRQMFSTSSIMRRTVQRREAIEGGTASSDLESTISQARSSGIPLGEPIRRQMEGAFGADFSGVRVHTNNTADTLNRSLSARAFTTGNNIFFKQGEYNPSSSSGKELLAHELTHTIQQGSVQRQATSIQPVSLTPIDPGVNSTIQGKYLENQQLFSKDTNLGTFYSRGALEAVDEALKAYEKTIIFPEVKDPTLASKPEHIDEKLKKLFKLKDVVEFWVFQHFDLKDASKAKTTRINPTLDLQEEITQAIKQQVKVYNQVKGLDASDQDVEDRLRSDSMDSALKSRVATLIDAILQPGALSKLSAEISLAIDVQPPGYVGFDLGLDVERKENDVLNIRSELAATGGVRVPKVFDIKAKLGGYVEAEAGDSRKTMNLISYGLYRKVVESKLMPASVAGVIWGGSFGESGQIMAAKLAADIERGVFGAEGGEEAFVDLGLLAGIGAEVGDKETLGGGVEYKYTTGQKYTKSSVESAGGLGKVTKEDVGNQGKKRKGEGTSAHEFTAKLSAGIFNGKVGYKKSGESQEITGSAQFSGIPDIVSFVLGVEGTINSFKSAYKNKEKSKKASDTIQGLDGLIGTLQTLAGDGAAISSIPTTSTKGEFAIKASKEGTSAWVIEIMFNQITGAPIPGDLGVVSVEVSKSDTRLKFSNKGGSWKTVHFG
>NC_019693|1270355:1317615|1303945_1305496_-|WP_052315694.1|DBSCAN-SWA
MNMKKSRLPIPIFCYWLLVIGHWSLFCLIFLPNPVFAARGSDVAKLEETGQCTRCNLQEANLMGAQLQGADMSDSNLRLANLRGAKLDGANFSRSRMFQADLSNATLGSATLEQAHLEKAIFNGATLFRANLHQANLEKAELLGANLNSANLELANLKEANLENADLQDATLPLANLEKANLKNANLKNANLSGANLKRVNLENANLESANLSSTNLEEAKLFRTNLKGTILNGETILDSKWQFIWTVVNQPLAGQTLAGSDLSGANLEAMNLTGINLEGANLEGTSLFMSNLERANLTGVNLSQSYLHYTDLTSANLVGANLHRADLRHSILLGTDLTRADLSHANFKGANLQDSNLFAANLEQSDLGNVNLLGANLGNANLRNILINEETAIESRWLFILDLIKQGAENQDLTEANLVEANLSGINLKGARLANANLQGADLSLANLETAHLFGANLQNANLSGANLTGANLGGANLTGANLEGVNLSQVYLCNAIMPNGIENRCNSEETNPNQ
>NC_019693|1270355:1317615|1280921_1282262_+|WP_015147429.1|DBSCAN-SWA
MSNYLAIATVTACLQRMLQSSVQLDLDGARVTTVRPNNLGSGTPEKGVNLYMYQVSLNPVWQKNAEVRMRSTRDAGAKKSRTALDLHYILSFYGNETELEPQRLLGSVVKILSDRTTLTRETIYETLADSSYPYLTDSNLADQTEEICFSPMDLSLEDLSKVWSVFFQTPYSISLVYKATVVMIEGEEAAYRALPVRERALSGVIPFINRPLVEQVVSRAGKFEPILANSTLIIRGKSLNNKQTKVRISGVEITPQSVNETELLVPLALTPDNSLKAGVQSLQVIHHVSTESRGENGNGWQGEWTHETATQTLSKPTVFSQTLESNAIPFILRPVVTKVTVSKLEGKDEDVRSAQIKVRVNLNLGKQQRIVLILNEKSTQNPAAYMFEAPNRHRDGMMVTIPVKNVKPGEYLVRLQVDGAESILNVDSDPNSPNFNRYTEPKMVIR
>NC_019693|1270355:1317615|1289772_1290768_+|WP_015147434.1|DBSCAN-SWA
MATETQHLTRQFELSFLLDAKDVLSAKVVDSKLFLVNQEPREYRITLEIDWLEYQRIVQAEGFNLTQAARSQAEALSFDENRPLKIELRLDENLFPDLIQNGNSVEELMNYLITRNQANKSSDFFNAHHWYVLDVNQGVHLPPDLEGVGELKMGYRTAWADEKNKPEDVIKIGDSRKSSQMNADHPILEIITEVLTQNNQPLYQWESDHVVSFPYQGKNEKWRCYADAREEMSLCCFYSIFPDAVPIEKRAPVAELLMRINYTLTVGNFEMDFEDGEVRFRTSIDVEGDRLSTQLFRQLTIANVTMMDRYLPAIRNLLKNDMSPTEAIAAI
>NC_019693|1270355:1317615|1298494_1299349_-|WP_015147443.1|DBSCAN-SWA
MQVLAQQAMLKSIDVRNQAGFDLNSPICIYGLCDKLKVKVRFVDISMEGIYLKGEEPEILLSALRPLPRRNFTCAHELGHHIFGHSSTIDELIEDSDKPKTFNPDEFLVDSFAGFLLMPILAVRKAFVSRGWDVAEATPVQIFTIACSFGVGYKTLIDHMTYALKMMSRSQAALLLKSTPKAIRQEILGRSSTDPLIVANAQWSLPTIDAEVGSQLLLPSLAEATKNTITVQADLPLGRLFRANRPGIVRVHCPNNKWAVFVRVSRYQFVGLSKYRHLEEVEDE
>NC_019693|1270355:1317615|1301047_1301380_-|WP_015147446.1|DBSCAN-SWA
MEIEKYRKLIKTIVEKQGDCDSDDCEVETQIAFDVERDRYLMFHVGWRGEKRVFGCVIHLEIREGKIWIQRDGTEIGIANELIAAGVPKSDIVLGYRSPYMRKFTELAVR
>NC_019693|1270355:1317615|1295244_1295649_+|WP_015147439.1|DBSCAN-SWA
MNIIGHGIDIIETQRIKKIIERFGNRFEARCFTEKECFAAECSTNRVQYFTGRFAAKEAVLKALGTGWAQGISWTDIEIERLSTGKPLVVLYGRCQEIAADLGIARWFLSISHTDSYAVASAIALGSMLVQADL
>NC_019693|1270355:1317615|1299755_1300049_-|WP_015147445.1|DBSCAN-SWA
MTSNEVEVKLIEVLQGIQSDSGYDGSGIVGTTCPLSNLEGFDSMLWPVAISMLADALDVNIPNDKNIFLSEDGKRPLNISESAAVVCEMVSRKENQG
>NC_019693|1270355:1317615|1315383_1317615_-|WP_015147455.1|plate|DBSCAN-SWA
MDFDFLPNLPKSDLDDRKFQDLVDECLLRIPRYCPEWTNYNPSDPGVTLVELFAWMTDQMLARFNQVPRRNYVTFLELLGVRLRPPTPAKTEVTFYMSASLPENYTIPAGTEVATVRTEEEEAIVFSTDAPVAVGKPRIRHLLTAPSAEQEPQILRDRFIGSWRMERTGEWQGLELPFFDDTPEPGNCFYLVFDSEALIEGNVIALTLKGEAATSTGINPDMPPRRWEGWNGEKWQPILLHESDDKTQGFSFSEIVRQGGDPLSGVDVVLHMPKTWPVTHFFTYQGRWIRCVYTQPATYQAGYTRSPRIVGLNARSIGGSVTASQSTLIRNEILGESDGNPGQTFQLQGVPVLPRREDEYILVTPIGGLPQIWQEVNDFSTSGPEDLHYTLDSLTGKVQFGPLIREPTQLREKMAWRASEQGARQGSLTLANGRPGDRNAFQPMTATGIESMERQYGAVPPRGANLQIVSYRTGGGLRGNVQAGTIQIVKSAVPYVAAVINHLPGRGGADSESLDEAVIRAPRMLRTRDRAVTVEDFETLTLEAGQGAVARTLCLPPTHKSEAGTVRMLLVPKPDTLSIERGEGIDPDLFNLSPVLINRVLTYLDDRRLLGVQVQCNQPNYMGVSVQTEVALKPEYKNPSAQQQIIFSMQVALYRFLNPLTGGPDGTGWPFGRPVYPSDIVTILQNIPGVLYLGSVQLFELRLRNGVWVRRLPPDPVINPGPLGLVCSWRNDTLRSGHTISVI
>NC_019693|1270355:1317615|1274726_1276052_+|WP_015147424.1|DBSCAN-SWA
MEPLSLGMFLSRSQVPSTSAIPEFSLEETRPLLNPTPSRSQSLAIESVCRQQIQQLIGYLPLVGAWIIYSDFEAEQPRRWVGEARGDRPEFNEEELSYLKSEVWLPDELPVDRLSQLNAYYVYPLPPLAAGGSTEYFPKIDLGRLSDCLSPLIVPPGDRSGSVAQKVPPQNHPSCALAQSRSYLLLWSTESLSPFQVEFVEQQMPMLHHYLRGAVVSNQQSSELQLLRQSLYKAEHQLRNSLALISLYAETLCLGLPTGSFQEQATVIRESVSELSANLTTLLNCGKPAHKLPEQRHDLRQIVEETLKLMQPKLQKKDIKVKASKISVMLPIDRWQIKQVFENLLNNAIAFSPLGSRITCEWQVFYHEVLVSLSDQGPGLSREDLQQAFTPFYTRRPGGTGLGLPIAKKIILDHQGSIWVQNHPESGALFSFTLPRHPQLD
>NC_019693|1270355:1317615|1310604_1312527_-|WP_015147452.1|DBSCAN-SWA
MVSIRKVLPALIVFPIFIAVGVTGWLSFRSGQQSVEMLVRKLGQEVSDRIESEVAAYMEQPQVLHELTLAAIRSGNLNVNNLQQIERYLWHQIRWNDSISSSFYGNESGEFIEINLTNDRNPVLRIREQETGPVSKTYQLDDQGNRLGEISVGEFDPRVRPWYRKAQATGEMTWSPIYRFAFQDSVLGIAAAAPVYGPGETLQGVFGIDIFLDELSNFLSNLEISPAGAAFIVERSGAIVASSVEENLFVEGENRPTDPLGNSNRLWAIESINPTIQGTARELLAQFNSLDTIQTPQNFKFSLDGKMQWVAVNSLQDDRGLDWLIVVIVPEADFMGYIYQNTRNTVVLSLVALVVATLLGIAIAKWLIQPILRLSATAHDIELGNFDPNSLTEVTNRSDEVGQLARIFQDMANKIYAREQGFKDQLSLLQTETDKAKKAMLLTQMSDSSYFQQLLIKSKRTRSKAEEFKKIDIAELLQKVSYFQSFSDAEIQRLIEMGYRKILYPGEYVCREDEPGDAFYIILEGSVEIFVEKIDKFLTNLGVGTFFGELSLLLGIPRTATVRTREDTVLFVLDREGLQKLLRNYKDLAEQIAQALHEHKAELESRKELLQKMGLLDDEEGFNQNPLGWIRNRMSTLFGL
>NC_019693|1270355:1317615|1290792_1291212_-|WP_015147435.1|DBSCAN-SWA
MLVGTKEVAKLLGVSSDRVRRLLLDGRVHGAYKISNVWVIPLKDGMPVITKGTRGPKPTWKGIRREVMTCIHVNRTRISQNYKHGENQPVIGVKRGSSNQYGYEVEVSGPCRVVYRPDQPKDCGAKVWIETLSEVKCVA
>NC_019693|1270355:1317615|1291639_1293001_+|WP_015147436.1|DBSCAN-SWA
MATGERIQKKWPNPAPTPRVRPFALQTPREVPQLQPQVREAPGSRSMPSYSAGDRLSGIDFSAQFPIQPKLITGAPQNKYEQEADCQEAGESIQGKLFSSPQIQRKIEPQEQSFTPVYLQTKPLTIQRDSGDRTDAQPLIKSEDIEYEIIGHRFAYQGDTLPAAAGDWLATRGYQRNWTLTIRGEGFFMGLLMPLEDGGRTPILAFKGTTPDWVDVSDILADLDPIAIGFTAFKRQQKKVAEAIATAGGKVDVVGHSLGGALAQHAASAFPNKVRRVVTFQAPAINRIQSYMFGKLDASERPEEVRHHIATGDIVDVAGGKHLAGDVLLHQVGSSPTSHTKYLLNSDAFKDQRDALGLTDEMLEQLGVAEHKANHKGKVEEFEEYPYWFRQILTEWGGRTVLGAVPGALLSAYRGGQKIGRGIAAGASYVGDKISSGASSIYDSTRNLLKNLF
>NC_019693|1270355:1317615|1299408_1299759_-|WP_015147444.1|DBSCAN-SWA
MTEAIGKKAIIASRIREARKMAGLSQAQVAQILGLHRPSISEIEAANRSVSAEEIAQLAEIFDVSASWLIGEGVDKIDVHDNKLQLAARELQKLKPEDLDRLLTLLASMRTGGNQQ
>NC_019693|1270355:1317615|1282610_1284608_+|WP_156823741.1|DBSCAN-SWA
MSGVRMSPTKTWTIANQEYLMAAIARVRSYLQIHIQRLNPEAEFVSLEEPARSWDLPTPPSLDELSDRFGLSGFERDILLLCAGMELDGTWGTLCATAQGDAQAQYPTFNLALDVLPSPNWMALTPVGGLRRWRLIDIGVGNALTQSPLRIDERVLHYLVGIEHPDERLVAAVSRIPIHVGEMDRLCASHRQLAEQVAGMLVSEELGKVPIVQLCGSDVASKRAIATAVCSAIGWNLHVMAGDVIPIALGEITELMRLWEREAFLNNSALLLDCDEVDSNDVARESAIARIIENYDNPLLITSRDRRHPRQRPLITFEVEQPTSQEQRELWVNTLGPDAAELNGQIETLVSHFSLSAPAIRAACLKTKGTNKIATDNSNEFGSQLWETCRIQARSRMEDLAQRIESGSQWEDLVLPDIQRDTLREIIAHVRQRAKVYETWGFGGKSGRGLGITALFAGASGTGKTMAADIIAQELHLDLYRIDLSSIISKYIGETEKNLRRVFDSAEAGGSILLFDEADALFGKRSEVKDSHDRHANIEVAYLLQRMEAYRGLAILTTNLKSSLDQAFLRRIRFVIQFPFPDANQREEIWRRIFPKQTPTEGLNYPKLGKLNVAGGNIRNIALNSAFIAADANEPVMMKHILEASKSEYMKLERPLTDMEVKGWI
>NC_019693|1270355:1317615|1271555_1272026_-|WP_015147421.1|tail|DBSCAN-SWA
MADLFVISSNRFSFTYGGKEFPLLKISGIDVQAKTAGHKSPIASGKNAQMSRQTVSTGYYNNQNITIEAVLQDGVKTLYDIFKKGLPATYGGDGKWSGNFSDAAITIFDPDAKEVLTYNLKQCQMVSYEVSEFNVSGDQFLTEKFELNVESVERKQ
>NC_019693|1270355:1317615|1270355_1270847_-|WP_015147419.1|tail|DBSCAN-SWA
MPEFPELLATSRFYLELHLKDSVDAIDAYFMECQGFKTSQEIIEICEVTPQMWGKDGKSRGRMIRTKIPGNISYTNLTLRRGLTVSMTVWNWLEAVQEGSWALQRRDGSLTLYDQGAQAQVRFEFKRAWPVSYSISDVSVSSGDLEIEELEVAVEELKRVKVV
>NC_019693|1270355:1317615|1276239_1276917_+|WP_015147425.1|DBSCAN-SWA
MMTPQLVSILLVDDDPIFRHGLKTLLSFYNNNGLFRMDVVGEAASVDQALKVTSQQHPALILLDLELAQTDGIEALLQLREQSFPGKAIVLSAHHEDEAVFRSMQAGARGYVFKESVAKQLWDAIATVMKDEVYLAPEVATSFFRIFHFYSGHSLQGCKNIRLTDREREVLEWLVKGASNEEIARHLYVTVATVKAHLTAIFEKLGVSSRTQAIVKALKVGLVAS
>NC_019693|1270355:1317615|1284796_1287256_+|WP_015147432.1|DBSCAN-SWA
MATGRQIQKKAQSNATPTPVTGIFKPRPFARAAEPEAATAPELQTKTELGQVRGDRLSRIDFSTPPPIQPKLAIGAPDDKYEQEADTIARKVVQQMSTPTPPDANGGGDAVQRQMFSTPSIMRLTVQRRKAREGGEASSDLESTISQARSSGMPLGEPIRRQMEGVFGADFSSVRVHTNNTADTLNRSLSARAFTTGNNIFFKQGEYNLSSSSGKELLAHELTHGVQQSGSSTIQCKLTPDQIKHANRIRKARGLKLLPVEEAQDLNTVEEASEAVPASVPAASVPAASAPSPPSDAKRKGAQFNIIQDYSWIRDTLQECQSWDNIKQKFASQKDSMWQFFDFRQWYVDSLINVLRDMYPGLIAKSVGSQDPTSDYDITISTPGSGDDVEAIQWFNTQVRKEFGVEPGTLFDTNLYAKDYLQVKENIDETAIAEQNSDTDLEQPDGAFGAMGHLSQDVAALVKQRRYMKQVEWDRYVDDVVQSINDPERKKLTRLQYEEADSVYQIFAHELLQEVEKESGLPEKIEEHSIKLGPEEEAALSQIKSPDDKLRSIIRQQLLGSEKLQAITHDNPDLVLQKSNELYLTRMRKVRQLQLTIRELGTQDKFVEQVKVLKAQVKQILGEACFFAAEAYHSEGAVKHIVAGIQGAKNPEQKAAIMSSLKPEHFLQSFNEQLGDFLKDLNHYAGEPDGKIFYRSSKYLYRLFLAVAELRQYQFTENNFALKIEEQRGNSDEIAKKINKDLVEIRKGNKADLDTDDKKNQAAEAAMQTILGVNKASELKIKILQMSTEFNTLVRTRASELSAPSLETSQTYFGNIVQN
>NC_019693|1270355:1317615|1277100_1278174_-|WP_015147426.1|DBSCAN-SWA
MLPNKTPSSALTHKPIPQPSPQIHEKHFQHLQGQFQARGEILFPCVPELLQLYLQQIAALLSSFNSVIEPSTLAKLPKELENQLISGFATSPHSKLIFTYEPSPQGVTLTLKPFISSVADQYQDWVKQREPPLFGTHPDAKVMAIAAQFADPADSPILDIGAGTGRNTLPLAQRGYPVDAVELTPAFIEQIQEAAQKQKLPVRGILGDILDRQVKLQPAYYQGVILCEVIASHFGSGDRLRQLFARICDTLRPGGLLLFSLFLAVDDYQPDNLTRELSQVTWSCIFTRSELAAAMERLPLTVLSDESVLEYEREHLPVAAWPPTGWFIKWCQGENLFPLHNQGKPPMELRWILCQRR
>NC_019693|1270355:1317615|1305580_1308280_-|WP_015147450.1|DBSCAN-SWA
MVMQGYSPNSGQIVNGFEENNSDRPMIRPIGIILNPAGVALVTAGEVLELTATITNQGSVSAIIDLFIAETSQPVHQWFVCPRERLALSPGQASEVVFRVQIPVDAIPGTYDYTLVIDAPQHYPEETPIDQKVRLQVMPFVQEARTVSDPTFTLQPPTSSVSPALLQPGQPLELQVTVHNRSDRVDRFFLTCPDLESRWFTIIYPEGFQQAGMAIASDGLELNPGDIGQILLFISPPPDTWAGVYAPTIRVYSANNPDLALLDVVYLQIASLHLVTVELLSLVAKIKREAGLFELKLSNQGNVIREIAIHAKSTDEEDICTYTIAPPMVRLLPGTSVTVGVSVKPTKGWRPFFGRMINFSIELEDLQQYPLINDRFQASLFWEPRPWWQFLPIVILMSASVAALIFLIWWLLTRPPVRAQVMQFSPESNSYQELNNEAIRLNWTISNPTHLKTVTVVGFSPDGLVRSGPFIYEFIPGLPNALDRFCTQGEQLICRNVWTDAREAGDYVFELTAIPINSKAETQTIRTNPIRILPVPQPKIEEFASTQPVYQERLLTPNTPANPTESTPTAPSTSSTQGNRILLNWALSHPDQIQEIRLLGLGPDGTVKSVEKRYNFAEGIPEELRGFCGENPASRQVICTNVPTDAIQPGDYIFHLTVVPKKGQPEPLETRRTNTIKILAQKIPSRIVEFTFNGQPAPPKLVRQANPQQNSLMISWKVEGGNGMKVELLPAPGTVPREGRMPYPVSQQPGSEMITLQVTDEEGNQQQRSVIIETLAPPPPPEPVEVPPPPAVEQAPAMVPTPGAMTGAEGDPAAAPAPGTPDAALVIPAPPTPGGDAVGPPPVELPVPGANLPGGVDPAAPGDTPDGAPDAAEEPVKEPGPQFFETQPLAPAELPPQFN
>NC_019693|1270355:1317615|1295675_1296554_-|WP_015147440.1|DBSCAN-SWA
MDFRQYQEEALKTDHIPAENDTKIIVPLLGLAGEAGELLSEYKKYLRDGEAHKLFPERVAEELGDLLWYIANLSSKFNLNLEEIAEGNIQKCRDRWGWRDLVETGAYIFDSDFPEHERLPRQFVVKITEVSENNSVKMKAFINGEQIGNDLTDNSYSSDGYRFHDIFHFSYAAVLGWSPVIRSNLKCKRKSDSKTDEVEDGGRAIAIEEGISALVFSYANKHNFLEGVKTLDYELLKTIKNMTEHLEVANCSLGDWEKAILNGYEVWRQVEKKRGGNVVVNLDERSIIYQDN
>NC_019693|1270355:1317615|1302229_1303924_-|WP_015147448.1|DBSCAN-SWA
MNKQLVKTGSNSVKIGISVLLMMAGMGVGSGNSRVLAQEGLEDFSHWAGLCRTFLEQGQYEEAVAACDAAIALNTNDPIVWSDRGDALFALTQYAEAVASYNQAIERDPNNSLLLTKRCSGAVELSQYEEAIASCDTALRMDNNWETQSPAVAWYHRGVALSRSGQIEEALTSYEWAIKINPNYSIALARRCAILSELGQGAEALTACDRALQVNQNWGTLNPAVAWANKARLLKSQRRYDEALAAYDRALGLEPNDAASWTEQGIILGILGRHPEAQLSFQWAVKINPQSSFTLLHQCANLNRLGSYEPAKAACEMALQEGDGNWGDLGPAYAWVQLANALTGLENYEESLAASNKAIGLNPQLADAWSNRSVPLWHLNREQEALAATERAIAVAPGSSLAWFNQGRILTGLGRYDEAVDAYNRALRGDANVGDRPTMADIWVNQSAVLYRLERYTEAVASADSALGMTPESAPALYNRALGLMALRRYGEAVTTYERAIQINAENADFWAGKGIALRFLEEYGDALAATQKALELNPTHSQALINQEIIMEEMNKPNPTSQN
>NC_019693|1270355:1317615|1308339_1310574_-|WP_015147451.1|DBSCAN-SWA
MATTVINTIVSTKELHFQPGGVPASFEVTVVNGSDRFASFQVELVAAGAAADRNGDWYSISPTASSKTPNGAATQFHVAILDTPVPGFVGMMNLRVRVFSMELPDETREILRLVVERGTGLIALQLELPVKQFQISPGSRIEVPVRVYNPGQLLSNALLTEVAIDPRWLPLSGERRLQVPPGKSIETSFTYQAPFGATAPSQAYPFIIEATHNNGPASQVSGTLEVMPMGFVEFTATPKQRAIPSKLHWKFWQSHPVTYSLEAKNASNLPQETTVELAGENSPECDLTLIPEASAIAPEETVEFLLTASKKRPWFGRNRKLLLELTGIWSDRRVDVRNEGHTLELVVKPVLPLGLQLLGGLFLLYLLWWLSWLNAKNPFIGHNEPVNTVQFNGVGERLISGSNDQTIIEWNISGFFNPIINQEMRKFPHKGNRLWQWLTHPFQNRGNCQSPGCTDLLAEKAVRVVQYRPVNNNWVATGLENGEIHFWNLTENRPDPLQSFVYQRDDRVFALEFTQDSRFLFSGHGSGSVLQWDLRNGERVNSNSEVMTPNLKQFNFAVYALKLVGNDDRTLAVAGQLNQFVLWNWQENTEAVVPYREGGKDAYINSLDTAEFNPNLVATADNQGYITLWNMQPCLNGGADCQRIEQWNDGHNGQPVRSVALSEDGCYLVSGGDDGRVMLWPLNMDGSRAGPQGEQILRAKNKNFNSVDIKEVDNHLLIAAGSDDQQEVRVESHPRLPNLGCDLP
>NC_019693|1270355:1317615|1294674_1295154_+|WP_015147438.1|DBSCAN-SWA
MKKGAVIDLMEIYRYSLWREWDANAPRVAFVMLNPSRADATHDDPTLRRCINFAQSWNYGSLEVVNLFAYRTSKPAELKKVTDPIGSENDYYLEKAIKSADKIIVAWGNHGIIRNRYREVLDWLTSFDELYCLGITQRGYPRHPLYVKSNTKPVFYKSK
>NC_019693|1270355:1317615|1312591_1314043_-|WP_015147453.1|DBSCAN-SWA
MTLPWLPPNIKPLNRLHVSDGLLIDAERWRLAHDYHRHRQNAHFQSLNQPGIVSDMGVRLIEPPNEIPSQYRDKRWVQVQPGIAIDLFGNLIVIPEPIDFRITSAALMGKPLMVYLVVSYVDPDGLVREENGNGDIVTESFRIDEKNSPPAEWEVELCRILLQPGEVELSTALDAWFPGVNNLDLRYRPQANARTQAVVRLAQVVKNTPEDAEIYANLAYLSQAIAGLYPVWQGFNEIGQFTLNSPSEINDLITYDVLYFKTQPSLALSPGEFDILRQYIEMGGVLLVEASIKGTKVEELIGLQHQLQEAIARLEMSLNLPTESNETPGKTAAASRNEQLANHLEIKKSLEEELISVKSSLSEEINTLSSAFKKFARDLGIPLEDLDTLSRNHPLRTQPFLFSALPTVNGQALKILTGGGIIIFIGNLSVAWGLDEKLSLGRETIRTAQEMGINILHYARTRRKLTQLQKAKEFQPIQVPDSI
>NC_019693|1270355:1317615|1274021_1274528_-|WP_015147423.1|DBSCAN-SWA
MIPAVAQTLAEILAGGTSAIRMEQIDFNSPTSGLNNQAARLNLYCYDVRENPQMQTTHRQTDPSTIWVDVSFLITAWDNTALGEQHLLSEALTILLPYHCLPSERLAPALQGKGTLPMRISADGLSEIAAIWTALGVPLRPGLYLTVTVPFTSQTEPAMKEIAFTSSQ
>NC_019693|1270355:1317615|1296587_1297694_-|WP_015147441.1|DBSCAN-SWA
MVTKRRKQVSEIEQNKQLTLEFGEYGNELSSAPEIISHILPAKPTAVFNTYWRFAAERQKIFFKKLEKAPMPWTDDPILSIYKFTNAYRASDRVSQYLIRHVIYQDELPSSLNEVFFRVILFKIFNKIETWQLLEDKLGSIIYAEYSFERYDQVLTDAIQSGQTIYSAAYIMPSGATSFGNAAKHRNHLKLIELMMANDLPKKLADAKTMHQGFDLLRDYPTIGDFLAYQFITDVNYSEITNFSEMEFVIPGPGALDGIRKCFSDLGGLNESEIIKFMADIQESEFERLGLNFQSLWGRKLQLIDCQNLFCEVDKYARMKHPDISGISGRTRIKQKYSGKGQPLDYWYPPKWGINQAIKESKKIKADI
>NC_019693|1270355:1317615|1278195_1279272_-|WP_015147427.1|DBSCAN-SWA
MYSDPVIDSPTPENQPLTNPPTLQPGPLVQLQHRFQGRGQIIMPCIPALLEHYLNSIAQLLNALGQTLDHDGVTHLSQSLWRKLQEGFETSPHAKIVLTYEPQPHDSSQLKFQVSLLTPGLAEEYQKWVKTKEPPLFGAYPDAKATAIAAQFDNPANAPIVDIGAGTGRNSIPLAQRGHPVDAVELAPIFIQDLQATAHHQNLPLRVIPGNILDRPLKLPPAYYQLAIVSEVISHFRDPCELRLLLAKLSDAVLTGGFILFNLFLPLQDYQPDRLVVELSQSSWCTLFTRAELATAMENLPLQLLSDESAFEYERDHLPASAWPPTSWYPTWSQGRNMFHLPNAFPPIELRWILCRRL
>NC_019693|1270355:1317615|1282385_1282610_+|WP_015147430.1|DBSCAN-SWA
MNEEELKKRLNQELDMMSINQLNELGNQAVKMGLIVGHGYRGGKYEILRKGEALMMTPQEAQSYLENLIKEIGG
>NC_019693|1270355:1317615|1279374_1280451_-|WP_015147428.1|DBSCAN-SWA
MTSQNPNHPTASVPVITDPDVLLQAMLTSFNQRLETVGELIMPGVPAMAEYYRHRIGSLFDSLAIPFQEAERNQLYQILDKKLEEGFALSPHARLRLKYHPADPPKTGLTFEFSVSVLSDIEEYQEWMNQNEQPWFGMTPDAKVLEIAELIEDPKTASVLDIGAATGRNTLALAQRGHPVDALELVPPYGDRLQQIAEQTGLPITVTAGDIFNPLVRMPLGQYQLAIATETLPLFCFDRDRLRLFLVKICDVLQTGGSVLFSLFLATEDYEPDPVTRQMSQVNWSCLFTRSDLATAMAGLPLELISDESWVNYEQTHRPEETWPPHESFLNWATGRELLLTPPDQTAMELRWILCKRL
>NC_019693|1270355:1317615|1301370_1301787_-|WP_015147447.1|DBSCAN-SWA
MSAKDIFHTVVRSALEKEGWTITDDPIYLKVDEDRLYVDLGAENNLLGAERSGQKIAVEIKSFLGLSLITDFHSAIGQSWNYKVVLAEQQPDRVLYLAVPEDIYEEFFTRRLAQMSVTRMQLNLLVFNPIREEIVLWR
>NC_019693|1270355:1317615|1270976_1271459_-|WP_015147420.1|tail|DBSCAN-SWA
MPVDKEPLSQARFEFAADGLGKDLLVESVSGVKMSIPVTNADGAFGVKTGSKVNRQAAPSAVESSDVTVTFVTSSKDPKAVSKWFYDSHSTPDLGGATGTKGKTDQATLTVFKQDGSASASWTFKGVMPMTYKMSDLDAAGNQSLKETITFCYEYVERTN

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015147419.1|1270355_1270847_-|tail	phage tail protein	NA	NA	NA	NA
WP_015147420.1|1270976_1271459_-|tail	T4-like virus tail tube protein gp19	NA	NA	NA	NA
WP_015147421.1|1271555_1272026_-|tail	T4-like virus tail tube protein gp19	NA	NA	NA	NA
WP_015147422.1|1272184_1273909_-|tail	phage tail sheath family protein	A0A127AW39	Bacillus_phage	2.4e-15	30.4
WP_015147423.1|1274021_1274528_-	DUF4255 domain-containing protein	NA	NA	NA	NA
WP_015147424.1|1274726_1276052_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_015147425.1|1276239_1276917_+	response regulator transcription factor	NA	NA	NA	NA
WP_015147426.1|1277100_1278174_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_015147427.1|1278195_1279272_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_015147428.1|1279374_1280451_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_015147429.1|1280921_1282262_+	DUF4255 domain-containing protein	NA	NA	NA	NA
WP_015147430.1|1282385_1282610_+	hypothetical protein	NA	NA	NA	NA
WP_156823741.1|1282610_1284608_+	AAA family ATPase	K9MCS8	Sulfolobus_virus	2.5e-08	32.6
WP_015147432.1|1284796_1287256_+	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_015147433.1|1287456_1289769_+	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_015147434.1|1289772_1290768_+	YbjN domain-containing protein	NA	NA	NA	NA
WP_015147435.1|1290792_1291212_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015147436.1|1291639_1293001_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_015147437.1|1293007_1293997_+	hypothetical protein	NA	NA	NA	NA
WP_015147438.1|1294674_1295154_+	DUF1643 domain-containing protein	A0A0F6WE62	Mycobacterium_phage	1.9e-31	46.7
WP_015147439.1|1295244_1295649_+	holo-[acyl-carrier-protein] synthase	NA	NA	NA	NA
WP_015147440.1|1295675_1296554_-	nucleoside triphosphate pyrophosphohydrolase family protein	A0A2H4J7H8	uncultured_Caudovirales_phage	2.3e-14	42.7
WP_015147441.1|1296587_1297694_-	hypothetical protein	A0A249XNQ1	Brevibacterium_phage	1.6e-33	34.8
WP_015147443.1|1298494_1299349_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_015147444.1|1299408_1299759_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015147445.1|1299755_1300049_-	hypothetical protein	NA	NA	NA	NA
WP_015147446.1|1301047_1301380_-	XisI protein	NA	NA	NA	NA
WP_015147447.1|1301370_1301787_-	XisH protein	NA	NA	NA	NA
WP_015147448.1|1302229_1303924_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_052315694.1|1303945_1305496_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_015147450.1|1305580_1308280_-	hypothetical protein	NA	NA	NA	NA
WP_015147451.1|1308339_1310574_-	hypothetical protein	NA	NA	NA	NA
WP_015147452.1|1310604_1312527_-	cyclic nucleotide-binding domain-containing protein	NA	NA	NA	NA
WP_015147453.1|1312591_1314043_-	hypothetical protein	NA	NA	NA	NA
WP_015147454.1|1314258_1315344_-|tail	phage tail protein	NA	NA	NA	NA
WP_015147455.1|1315383_1317615_-|plate	putative baseplate assembly protein	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_019693|1667210:1742727|DBSCAN-SWA
GTTAAGCGGATTCTGGTTTCGGTAAGGAGGACGGATGGACAATCAGTTCCGCGGTTGAGCGTTTCTCGACCATCTCTCGGGTAATGGTGCAGCGAGTCACATCCTTACGGGATGGCAACTCGTACATCACATCGAGCATTAATTCCTCCACAATTCCGCGCAGTGCTCTGGCCCCAGTTTTCCGCCGGTACGCTTCCTGGGCGATCGCCCGAATGGCATCGGGTTTGAACTCCAGATTCACGTTATCCATCCGCAGTAATTTTTGATACTGCTTCACCAGGGCGTTCTTGGGTTCCGTTAAGATTTCCGTGAGGGCATCTTCATCGAGGGGGTCCACCACCGCCAGCACTGGAATCCGACCGATGAATTCAGGAATCATCCCAAATTTCACCAAATCATCCGGCTGTAAATTCTTGAGAATATCGGCGGTGCGTTTTTCCTTCGACTGAGCATCTCCGGGTTGAATAAAGCCCATTGACTTTTTACCCGTGCGCTGTTCAACCACCTTTTCCAGACCCACAAAGGCTCCACCACAGATAAACAGAATATTGCTCGTGTCAATCTGGATGCAATCTTGATAGGGGTGTTTGCGTCCTCCTTGCGGGGGGACATTGGCGACGGTTCCTTCCAGCATCTTCAGCAGAGCTTGTTGAACCCCTTCACCGGACACATCTCGGGTAATTGATGGGTTTTCACTCTTGCGGGCGATTTTGTCAATTTCATCGATATAGATGATGCCGCGTTGGGCTTCTTCTACATCGAGATCAGCGACTTGGAGTAATCGCAACAAGATATTTTCCACATCTTCGCCGACATACCCCGCTTCGGTTAAGGTTGTCGCATCGGCAACAGCAAAGGGAACCTCCAGAACATCGGCCAAGGTTTGAGCCAATAGGGTCTTCCCACAACCTGTTGGGCCAATGAGCAGAATGTTCGACTTTTGCAGTTCGACTGGATCCTCAGCCCCAATTTTCCCGCTGGCCTTCGCTTGCGTGTAGCTCAGGCGCTTGTAATGGTTATAAACCGCGACGGAAAGCACTTTTTTGGCTTCATCTTGACCAATCACGTGCTCATCGAGATGTTTTTTGATCTCGCGCGGTTTAGGCATTTGATTCAGCGAGATATTCGCGGCTCTAGTGCGCCGCTTTTGGGGTTGTTCCGTCCGGGGTACGGGTTGAGGTGCTGCGGCATTGGAGTCAAATAGCTCCTCATCTAAAATTTCATTGCACAGGTCCACGCATTCATCGCAAATATAAACTCCCGGACCTGCGATTAATTTGCGTACTTGCTCCTGAGATTTGCCACAAAAGGAACATTTTAGATGGGAGTCGTACTTAGACATAGACGGCCTCTTACTTTTGTGCGGTAACAGCCTCTCCCGATTTCGGAAGACCCTGCTTGGTAATAACCTGGTCAATTAGACCATAAGCTCTGGACTCTTCTGCCGACATAAAGAAATCCCGATCGGTGTCGGCTTCAATTCGCTCTAGGGGTTGTCCGGTATGAAAAGCCAGCATTTCATTTAACTGACGTTTATGATAAAGAATTTCCTTCGCTTGGATCTCAATATCAACCGCTTGCCCCTGAGCCCCACCGAGAGGTTGGTGAATCATAATCCGGGAAGAAGGCAGTGACATCCGTTTGCCTTTTGCGCCTGCGGTGAGCAAAAAGGCCCCCATACTGGCAGCCAAGCCATAACAGATGGTCGCCACATCCGGGCGAATCTGTTGCATGGTATCGTAAATCGCCATTCCTGCGGTGACTGAGCCACCAGGGGAGTTGATATAAAGCTGAATATCCTTTTCCGGGTCTTCTGCATCTAAAAAGAGCATCTGCGCCACGATTAAGTCAGCAACGTTGTCATCAACTGGGGTCCCCAGAAACACGATTCTTTCCCGGAGTAGGCGCGAATAAAGGTCAAACCCGCGTTCCCCCATCCCGGATTGTTCCACCACCATTGGGATCACGTTCTGGCTGGTGGAGGCAATCTCTAGGCTCTCGGAGCCGGAGATTGGATAATAAGGAGTTTGAGATATAAGCATCCGATCTGAGTTCATGCCAGGGTCAGCTTTTCGAGGGAGTAGATATCAAGCAAATTTTTTTTGGTTTTTACGCCATTATAGTCTTTGCTCTGTCTATATTATGCCGCAGCGCACCGAGGACGGGCAGAAATTTCCATAAAAATCCACAAATTGGATTTTTCTTTAGAATCACCTCGCAATTGATTTGGAAATTTCTGGGGTTCTCGGTTCTTGCAAGAGGGCGATCGCGCTGCGGGTCTCGTCGCGGACCCTGGCTTAAATGGGTTTATTCTGGCGAGTCGATTGCCTCAACTTCGACCACTTCACCGACACTTTCTTCCCCTTCTGCGAGTTCTGCTTCGGCGGCTGCGGCTGCGGCTGCTGCTTCTGCCTCTAAGGTTCCTGCGGGTAATAGCTCAATCTGCGCCCGTTCTTCCAGCCAATCCAGGGCTTTTTCCTTGAGCATTTCTGATTCGAGGGCGGAGATCAAGCGATCGCGATCAAAATCCGGTGGCAAGCGGTCCTTGAGTTCCTCAATCCGAGCGTTGACTTCCTCTGCGGTGACGGAGAGGGACTCACGAGCGGCCACTTCTTTCAAGGCGAAGGATTTCCGTAAGTTGGCGATCGCCTCGGGTTGGGACTGCTGGCGCAGTGCCGCCACGGTTTCCTTGGTGTACAGCTTTTTGACATCAATCCCATAATTGGCAAGCTGCATCATGGATTGCTGCAAGATATTATCCAACTCGCGATCGATTAAAGTTTCCGGAAGTTCTACTTCCACCACTTTTTCGATCGCCTCCACTAAGGCAGCGTGCTTATTGGCTTTGGTTTCGCGATCGGCTTTCTCCTGATACTGCTTCTCCAAAGACTCCCGCAGTTCTGCGATCGTTTGATACTCGCTCACCGCTTGAGCGAAATCATCATCTAATTCCGGCAACTCTTTTTCTTTGAGTTCTTTCACCGTAATCGTAAAAATTGCTTCCTTCCCAGCTAAATCCTCGTTGGGATAATCTTCCGGAAAAGGAACGTTTAACTCTTTCGTTTCCCCAACTGTCAAACCAATAATTCCCTCAACGAAGCCCTTGATAAACCGGCCTTCACTGAGTTCAATTTGAAAGTTCTCGGCCTCTCCTCCCGGCAAGGGTTCAGGTTCCCCACCTTCTTCGTTGATGATTTTGCCGACATAATCAACAATGGCCACATCTTCAGCTTGGGCGGCTCTTTCCTCTACGGGAATTAAGGTCGCTTGCTCTTTGCGACGTTCTTCTAAAAACTGATCCACTTCTGCCGGATCATATTTGATTTCTTCGGCTCTAATGGCCAGTCCGGTGTACTCGTTCAGAGTGACTTCCGGTGGGACATCAACGGAAACTGAAAAGACCAGGGATTCGCCCGGTTCGTACTTCGTGACTAATTCATCAAAAGAGGAGATTAACTGAAAATTCCCCAAGGCCGGAATCTCTTCATCCTTGACGATTTTTTCTAGAGAATTTTGAATTAAATCCTCGACTGCTGCGGCTTTGATCCTGGAAGTTCCCATGCGCTGTACCAACACTGAGCGCGGTACTTTTCCTTTCCGAAACCCAGGAATGCTAGCCTGACGGCTAAATTGCTGAATCACCTGTTCGTAGGCTTTCTGAGACATATCGGGGGTCACTTCAATTTCCAGACCAAGTTTGCTGGCGGGAAGCTTTTCCTGGGTAACTTTCATGGGCGTTCTCTTCGACAAATTCTGTTAATTCTCGATTGATTTTTTGGGCGGTTTACCGTCCTGATTCCGTTGAGCAGAAGGGATTTCCTCCTGGTCTGATGACTGGACCTCGGCCCAAGGCAGGCCCACTGACCAGAGGTAAGTCCTGCGGCCATCGCGCTCAAGATCGGGCAACTCGGTCAAGCCCAAGGCTATCTTTGCTGCAACTATAGATCCTAGCCGATCGAGGGCGTCAAGGGCGATCGCCTTGGCATAAAAAACCCCGGGTCTCGGGAATGTTCCCCCTGTCACAACGGGCTATGCAGCTATTTTAGGGAGAATCTAAAATTTTACCAAAAAAAGTGCTGGAGTAATTTTTTTCGGGCGATCGCTGTTGTGAAGCGTTCCCCACCCTGGGCCCAGACTCCAGAAAGCCCGTCCCGTTATATTGAGGGTTCATACGGAATCCCGTTTTTAAAGGTCTATAAACACTAGCGCTGTCAAGGTGTATTGATTTGTAGGGGCGCAATGCTTGCGCCCTCTCAAGGTGTATTGATTTGTAGGGGCGCAATGCTTGCGCCCTCTCAAGGTGTATTGATTTGTAGGGGCGCAATGCTTGCGCCCCAGGGACGCTTCGAGAAGCGCCCCTACAAGAAATAACGATTTTTTGTCATGGAATTGAGGGCGCAAGCATTGCGCCCCTACAAGAAATAACGATTTTTCGTCATGGAATTGAGGGCGCAAGCATTGCGCCCCTACAAGAAATAACGATTTTTCGTCATGGAATTGAGCACGTTGACGGGGCTAGTCTATAAACACCCACACCCGTTAACGGTGGGGCACTCGCAGACGAAGCGGTGCCTGCGCGGGCTGAAGAGAAAATTGATTTTTTACAACCGGATTTGGTATCAATTTGATGATCGGCCCTTCCCTGGGTAGAATGATGGAATCCGCTTGGCCGTGAACAACCCGGAGGAACTCGCCCCTGAACCCCCAGGATCTGGCTTGGGTACGATCGCCAAGGAATCTGAAAAATTTTTAGCCAATCATGAGTATAATAAGATAACCGTTATTTTACTGAAGGCTATTTTTTATTGACTTTCTGTTTCTAATCTGCAATAAATACATTGTTATCCTTAAATAAACTATCCAATCCGTACAGGATAAAATAGGGGGTTGCTCATAGCCATCAATCCCAAGCCAGACTCTTTAGAGTCAGAGGTAGAAGTCAATTCCTTGGCAATCGCCAGGACCCAGGCCCTTTTAAAACCGTTGTAAGGAAAACACCCGATATCTATTTAAGACCTATTTGAATCGCATCTATTATTACTCAAGACTCTTATCTGAACCTGTGTGGAGGACTGTCATTTGTCGAAATCTTATAAAGTAGCCATTCTCGGCGCAACGGGTGCCGTGGGGACTGAATTGTTAGAGTTGCTGGACTCTCGCGCCTTTCCGATGTCCGAGTTAAAACTGTTAGCTTCCTCGCGATCGGCAGGCAAAACCTTGACCTTCCGAGGGGAAGAAATTCCCGTGGAAGTTGTGGAAGAAAGTTCGTTTAAGAACGTGGATCTGGTCCTGGCTTCAGCCGGTGGCTCCACTTCTAAGGCTTGGGCCTCCAAAGCTGTCGCCGCTGGTGCCGTGGTGGTGGATAACTCCAGTGCCTTTCGCATGGATCCCAATGTCCCCCTGGTGGTTCCAGAAGTGAACCCAGAAGCAGCAGCGCACCATCAAGGCATTATTGCTAATCCCAATTGCACGACAATTTTGATGGCGGTGGCAGTATGGCCCCTGCATCAAGTCCAGCCGGTACAGCGGATTGTGGCAGCCACTTACCAATCTGCCAGTGGGGCCGGTGCCAGGGCGATGGAGGAAATGAAAGACCAGGCGACAGCTATTTTGCAAGGTCAAACGCCGAAAACGGAGATTTTCCCTTATCCTTTGGCCTTTAATTTGTTCCCGCATAATTCACCCCTGAATGACCAAGGGTATTGCGAGGAAGAAATGAAAATGGTCAATGAGACTCGCAAAATATTTGGGGATCCTGACATTAGAATTAGCCCAACTTGTGTGCGAGTTCCTGTGCTGCGAGCGCATTCGGAGGCGTTGAACTTAGAATTTGCCCAGCCTTTTAGCGTATCGAAGGCTCGGGAAATTTTAGCTGCTGCTCCTGGAGTTAAGTTGGTGGAAGACTGGCAGGCGAATTATTTCCCCATGCCAATGGAAGCAACGGGTCGCGATGAAGTGTTGGTGGGTCGGATTCGGCAGGATATTTCTGCGCCGAATGGGTTAGAACTATGGCTGAGTGGCGATCAAATTCGCAAGGGGGCCGCGTTAAATGCGGTACAAATTGCTGAATTGTTGGTGACTCGAAATTGGATTCGACCGGCAGCGGCTGTCTCTGTTTAGAATGCCGGGGTGAATGACATCTACAAGCTGACTCGGAGTTAAGGTTCGAGGTTAGCACGGATGTTGTAGTCCAAGATGGAGACGATCGCCCTTTGGAGTTCCTTTCTGTAGGGTCGGAAATGCTACTTAGTCTATACCCCTTGGTTAGCCTTAGTGTTGAACGGTTCCTCTGAAATGGCGATCGCCTCGCCGGACTTGCTCGATCCAGTCTGCACCGTGAAACAGCATCAAGCATGACAGATGTGGGATAGCGTTCCATCTGTTAGATTTTACAGTTTGACCTAGGGTCGAAGTTTCATGCATTGGGGAAAGACTCCTCCAAACCGCGCGATCGCGACCCGATTGATCAACAACCTGAATACACAACTGATAAAACATAAGGAGAGCGTGGTGAATTTCGGACGAGTTGTCACCGCAATGATTACACCGTTTAATGCAGACGGTAGCGTGAACTATGGGGTTACAGAAAAGCTGGCGGTTCATTTAATTGAACATGGGAGTGATGCCGTGCTCGTTTGTGGTACGACGGGAGAATCACCAACCCTAACCTGGGAGGAAGAGTATGAATTATTTCAGGTGGTGAAAAAGGCCGTGGGTAACCGAGGGAAAGTGATTGCTGGAACCGGATCGAATTCTACCCGGGAGGCGATCGCAGCGACGGAGAAAGCTGCTAATATAGGATTAGATGGCTCGCTGCAAGTTGTTCCCTATTACAACAAACCCCCACAAGAAGGGTTATATCGGCACTTTAAGGCGATCGCGCAAAGCTGCCCTGATTTCCCAATCATGCTCTATAACATTCCTGGGCGGACGGGTCAAAACCTGCTTCCGGAAACGGTCGCCCGTCTAGCTGAGATTCCGAACATCACAGCAATTAAAGAAGCCAGTGGCAGCTTAGACCAAGCCAGCTTGGTCAGAAGCCTGACTCCACCAGAGTTTCAAATTTACTCTGGGGATGATTCTTTAACCTTACCCCTGCTGTCCATCGGGGCTGCTGGAGTGGTCAGCGTGGCCTCGCATCTGGTCGGAGAGACCCTCCAATCCATGATTCAAGCATACGAAACTGGGAAAAACCAAGAAGCAACTCAGCTTCACCTCAAGCTTTTACCCTTATTCAAAGCCCTATTTACCACGACCAATCCCATTCCCCTCAAGTGTGCTTTAGCCCTGCAAGGGTGGGACGTGGGATCGACTCGTCCCCCGCTATGCGAAGCATCGGATGAAGTCAAAAAAGCCTTAGAGGTCGTGATGCAGCAACTTAATTTGCTGGAACTCTAGCCCAAAGAAACACCGTGGCACTTTTTTGTCATCGGTTATAAATTCTCATCTTTAGTTTCATCACAACCCGACCAACTCTCGATAACCAATCAACCATAAAAGAGAACACAGAAAAATGACTAACAGCCCAATTACACTCGCCAAAGAAAAGAAAACCGTCAGTAAAAATGGCTCCACGTCCAATGGATCCAATGTATCCGGACCCACCCTGAAAATTATTCCCTTGGGTGGATTGCATGAAATCGGCAAAAATACTTGCGTTTTTGAGTTTGAGGACGAAATCATCCTCGTCGATGCCGGTTTAGCCTTCCCCACCGATGGGATGCATGGGGTGAACATCGTCCTCCCCGACATGACCTACCTCCGGGAAAATCGCGATAAAATCAAAGGCATGGTCGTCACTCATGGTCATGAAGACCACATTGGCGGGATTGCCTTTCATTTAAAACAGTTTGATATCCCGGTGATTTATGGTCCCCGCTTGGCAATGAGCTTGCTAGAAGGCAAGTTAGAAGAAGCCGGAGTCAGCGATCGCACCGAACTCCGAAGCGTTTCCCCTCGGGATGTGGTCCGCTTTGGTAAACATTTTGTCGTTGAATATATTCGCAATACCCACTCGATGGCGGATAGCTTCACCGTGGCGATTCATACCCCCGTCGGCATCGTCATCCACACCGGCGACTTCAAAATCGACCATACCCCCGTTGATGGCGAACATTTTGACTTGCAACGACTGGCGGAATATGGGGAGAAAGGGATACTCTGCCTGATTAGTGATTCCACCAATGCCGAAGTCCCTGGCTATACGCCATCGGAGCGATCGGTGTATCCAAATCTCGATCGCGTCTTTTCTCAGGCAGAGGGTCGAATCTTAGTCACCACCTTTGCCTCATCGGTCCATCGACTGAATATTATTCTGGACTTGGCGAAAAAACAAGGTCGCACCGTCGCAGTCGTAGGGCGATCGATGCTCAATGTCATCGCCCACGCCCGCAACCTAGGATATATTAAGTGCGAAGACAGTTTATTCCAACCCTTGCACGCCATTCGCTCACTACCAGATAACAAGGTACTGATTTTGACCACTGGCTCTCAAGGTGAGCCGATGTCTGCTCTCACAAGGATTGCCAACGGTGAACACCGGAAAATTAAAATCCGCAAGGGAGATACCGTTGTATTCTCAGCGAACCCAATTCCCGGCAATACGATCGCCGTGGTGAATACCATCGACAAACTGATGATACAAGGTGCAAACGTCATCTACGGACGGAATCAAGGCATTCACGTCTCGGGTCATGGTTGCCAAGAGGAACATAAGTTAATGCTGGCATTGACTCGTCCGAAGTTCTTCCTCCCATTCCACGGCGAACATCGGATGCTGGTACAGCACGCGAAAATTGCCCAAAGTATGGGAATTCCCGCCGAAAATATGGTGATTATCAATAATGGCGATATGGTCGGATTGACGACGGATAGTATCGGCGTCATCGACCAAGTACCGTCCGGGATTGAACTGGTGGATGCCTCTCGTTCGGGAGTGGTTAAGGATGAAGTGCTCAAAGAACGGCAACAGTTGGCAGCGGATGGAGTTGTTACCATTGCAGCGGCGATCGGTTGGGATGGTAAACTGGCCGCTGACACGGCAACTCACTTACGCGGGGTGGTGTCATCCATTGATCCGAATCTCCTGAAAAAATGGATTGGTCAAACGATTGAGGGAGTTTTGAGCGATCGCTGGTCTGAGTTCTCTCGCACCCTGGAAGATGGGACTCCCGAAGTTGACTGGACAGGACTGCAAAATCAGCTTGAGCGCGATGTGCAGCGGATGTTACGCCGGGAACTGCAAAGTAATCCGTTGCTGGTGTTCTTGATGCAAAACCCCCAAGAACCGCCAACGGTACAAGAACAACCGGCTACCACCGGACGCCGACGCACGCGATCGACTGCGAAAGTTGCGTCTTAGTCTAAGAAATAGACCCCAGGCTCAAGCCTGGGGCTATACAAACAAAGCCCGCCTGCGCGGGCTAATTTTTTGGATTTATATCAAATCCGATTGTAACAAGCTAGTTTTTAGAGACCTATCACAACCGGATTCCGTCCAGATTAAGCTATAATCAATCCTGTATCTTCGTTTGTGCGATGGAAGCAAATTGCCATGAATGATTCATCGTCCTCAATTGCTCAATCTATCTTAGAATTCGTCCGTCATAGCGTTCCAGGGTACGGAATCCGGGGAGGGTTCGGAGTGGCTGCACTGTTGATGACCCTGACTTTGGGCTATAATTCTGACTCTCAAACCTTTGCGGGGGATCATCCTGCTGTAGCCAATAGACAGGCGATCGCAAATTATCAGAGTCCTCCGCTACGGGACTCGGGATGGGGTGAAGTCGGGGTGGATACTCCCTTTAACCGCGATCGCATCCAGGCCCTGTTTCCCAACTATCGGGTTGAATCCAGCCAAATTTCTCGGGAAGGTATGCCTCAACCTGTTATCGAAGTCTACGACGACAGTATCCTAGTTGCTCGAATGGACCCCCAAGACGCCAATAATCCCAACCTCGGCATCCTGCGGATCACCATCTATGATGAATCCATCGCCGGACCCGGGGGAGTAACTATTGGCACATCTTACAACCAAACCCCTGGTTCTAGTCGATTTGACTGCTTCCCTGGAGAGGGACCAACTACAGGCTACGTGATTTGCCGTTCCCCAGAGAGCGCTCGGATTCAATATATTTATGGTCCGATCAATAGGGAAAGAGTTCGTCCTATGATGGAACTTCCCCCAGAAAACGTCCTCGGAAATTACCGCCTTGATCGCCTCGTCTGGTTGAATTGGCAGGGACGATAAATCAATCAGGGATTGTTTTGGACGGATTATTCATCGATTTTTCCATTTTTTATAAAAACCACTCTGCCTTGAAGCAATTAATTATTTAATTATTTTATCTTAATTAATTTTTTAAATTCTTCTAAGGTAGGGGTAGGTTTTATTCTATGGATCATCCGGTGGCAGTTAGAGCATAGAACAGTAAAATCTTTGCGGGGATCTAGTTGTACTTTGGTTTTGGATAAACTAGAAATTGGGACAATATGATGAGCTTCGATATAACGATGTCCAATCGTTCCATAGTGAGCCTCAAAATCAAACTTACAGGCTTTGCAAATATATCCATGTATTTCTTTTGCTCTTTTTGATAAAGATTGATTTCTTTCTACTTGTCGATGAATTCTATATTTTGTTAAATCTTCGCTCCAAAATTCTTCAGATACCGAATCTAATTCCTGGTTATCTGAAATTTTATGCTCAACCAGTTCTTCGTAAATTTTGATAAAAGATAAAATATCTGCATACATTTTTTCCGACGATGGTAGATTTACTTGGGAGTAATAAAGCGATAATATATGACCCGCTTCGTAGGCTTGACCTAGCCGTCTAGCTGTAGTTTCTTTAGGAATAGTATCCAGCTTTAAATCTATATCTTCATGTAATTCTAACTGGAAGTCATTAGAAATCATCCCTCTAAATACTTTGGCTTGCTTTCGTAAAATTTCCCTAGAAACCCCAAGTCCATAAATTTTCTTTTTGGAGTCGGTTCCTTGAAGTAGAGATAGATACACACCCGAAAAATCCGCGCAGAAAAGGTAGGCAGTGAAAAACCCGACCCTAACGCTATCAGTTACTAAATTATTAAAAACTGCAATCCAAGGTATCGTAGCCCAAGCTCCATTACCTGCTGAAGATTGGATTTTGTAAATCTCTGGTAGATTCAAATATCTAGTTAACAAGGGGGCTATATCATTCCTCATATAGCTTGCAAATGGATGATTTTTGAAATCTTCTTTATTAGCCTGTGGATATTCCCGAAGAACAGTTTCAATAACCGCTTTGAGCATGATAAATTCTTGTATTTGATAAAATAAATCTCTACAACAAAATTATAGGATAAAGCTTTTTGGGCTGAATTACCGTCCTTTCGGTTCCGGAATTGGACGCCCTAATGCCTGCGCTGTCTCTATCCACTCCTGCATAATGACTTCTACATGAGTCAACGCTTCCTGATAGGTTGCAGCATCAGCAGCACAACCCGGCAATTCTGGCACTTCCGCAATAAATGCCTCGTCCTCCTGACTTCAATACATGATAATTTCATACCGTAGCATCCCCTTCACCTCTGCCCTTTATGAAGTGAATAAAAAATTTCCTTCGTTAAAACTATAGCAAAATCGCTTTTTGTCTACTCCCATAAGCCTCGAAGATTATTAAAGTTAATTGTATCAATCCCTATCTTTTGCAGATAATTCGCTAATTTAAAATCGTCAGTGAGTACCAGATATTTATCTCGGGAAACTTCGATAATTCCGCAATCAGTCAACCCAAACTTTTTAAAATTATCTGCCCTTCCTACCGTGGCACTTTCAATATAAAACTCATCTAGCTTGGTGAGTCCTTGCCCCAGGATTTGCAAACATTGAGAGCGCTCTGGTTCGCCAATTTGATTGACAAGGCTATTGACTTCTGTTAGAATGTTAGGAGTAGTAACTATCTTATTGAAATACTCTAAAACTTTTAAAATTATATCATAATCTTCGGGTAAAAACTTTTCGGTTCGGCTAAATTTTGAAATGCGACTTCTGTTGACAGTGCCTACACACCATAGCAGAAGGATATTAGTATCTATCACTATACCTTTGCTTTTATAGTGTTTAAACACTTGGCTAACATAATCGTTCATACTTCTCTAATTTTCATAGATTCTACGTTTCCCGTGTCAGCATTAATTTTAAAAATTTTATAATTCCTTTCCCATTCTTGCGTCCTTACGACTTCTGGAAGTAACGGATTTCTCATCGCCGATTTTGGCAAATCATATCCAATTGTAACAAACCAGTATTTTTTATCTTCTGAAAGTTCAACTTCTTCCAACCTTAAATCCTGGATATCTAATGGGCCATTTTGACTCATCAAATCTTGCACAGAATTAAAATAATCTCGGGCAGCCAAGATAGCTTTTCGCACGTCAATCATGGTGAACTCTCCGGGTTAGTGTTTTCAATCTTACAGTTCGAGAAGGGGCAGATGGAAGCATCTGCCCCTCCCTAACTCAAACTAAGTCTATTCTATCCCTTCAATCCGGTCCTCCACTTCCTGATACAACTCGCGCAGGCGGTCTAAATTCTCCTCACTGGTTTCCCAGTACCCGCGTCCATTGGCTTCTAGCAAGGTGGTGACCATCTTGCGGAACGAGTTCGGATTCAGGTTCAGCAGGCGTTTCTGCATCTCCTCATCCTTCATAAAGGTTTCGTTCGCTTCCTCGTACACCCAGTTATCGACAGCACCTGCTGTCGCACTCCATCCCATTGTATTCACGAGGCGTTTCGAGAGTTCGCGGACGCCTTCGTAGCCGTGGGAGAGCATTCCCTCGTACCACTTGGGATTGAGCATCTTGGTGCGCGTATCTAAGCGGACGGTTTCCGATAGGGTTCGCACTTGGGCGTTGGCGGTGGTGGTGTCGGCGATGTAGGCTGCGGGTTTCTTGCCGTCGCCGCGTAAGGTGCCGATCACTTTGGTCGGGTCGGAATCGAAGTAGTGAGAAACGTCGGTGAGACTGATTTCCGAAGAATCCAAGTTTTGGAATGTGACATCCGCCGTTTTCAAGGAAGACTCGAAAATCTGACGGTCCTGTTCCATTGTTCCCGGATTATCCGAGGAGAAGGCAAAGGATTTACGGGTGAGATACATTTCCTGTAACTCGTTCTCGCTTTCCCAGGTGCTATTCTCCACTGCTAGGTTGACGTTGGAGGCGTAGGAACCGGAAGCGTTAGAAAAGACGCGGGTGGCGGCTTGGCGCAGGTTGATTCCCATCTCTTCCGCTTGTTTCATCGCGTGTTTACGGATGAAGTTCATCTCTAATGGTTCGTCGGCTTCAGCGGCCATTTTCACCGCTTTGTCTAACAGGTTCATTTGGTTAATGAACAAGTCACGGAAGACGCCGGAACAGTTGATCACCACGTCGATGCGGGGACGTCCTAACTCTTCTAAGGACAGCAGTTCCAGTTTGTTGACTCGTCCTAATGCATCGGGAACGGGTTTGACTCCCACCATCCACATGATTTGGGCGAGGGATTCCCCGTAGGTTTTGATGTTGTCGGTTCCCCAGAGGACGCAGGCGATGGTTTCGGGCCATTCTCCGTTATTTTCTCGCCGTTGCCGGTCTAACAGCCGGTCTACGACGATTTTGGCCGAGGTGACTGCGGCGGCGGTGGGGATGGATTGGGGGTCGAGGGCGTGGATGTTTTTGCCGGTAGGGAGCACATCCGGGTTACGGATGGGGTCGCCACCGGGTCCGGGGAGGACATATTCCCCTTCTAAGGCGCGCAATAAGGCCCCGAGTTCGTTGTCGGCGCAGACTTGCTGGAGGCAGAATTCCAGGTACTCAAACAGGGGTTTGAGGTCGTCGTTGCTGACGTTGGGATATCCCGATTGGTGCAGGGATTCGACCCAGGGGGCTTTTTTGCCCATGTTGAAGAAGTTGAGTTTGGAGACTCGGGAGACTCGTCCTTCGGCATCGGTTTGTTCTTGGACGAGGGCGGCGACTGCGGCGCGAGTGGCTTGAATAATCGCTTGTAACAGTTCGACGTCTTCTAGGATGCCTTTATCGTTGTTGGCATAGAGTTCGTCGATGTCCCGTCCGATGCTGTTGGCGATAATGCGTAGCAGACTCTTGACGCCTTCTTCGTCGCGATCGAGGGAGGCGATGTTGACTAAGGTGGCGATCGCCTCTTCAGCAGAAGGCGGTTTACCAATCACGTGCAACCCACAGGGTAACAACCGCGATTCGATTTCCATCAGCTTGCGGTAGACTTGACCCACTACATTATCCCGTTCCTCGGGAGTCAGTTCGATCGCATCTTTCTCGGGTAAGTTGATATCCTGATCCAAATTCACCAACCGGCATTTATCCATGATGGTGTTAACGATCGCCACTCCCCGTCCACTCTCTTTCAGAGTTTGATAGGACCCAATCAACTCATTCAGTTCTTGCAGTCCCTTGTATAACCCCGCATTCTCTGCCGGTGGCGTCAAATAGCTAATCGTTTCAGCATAGGACCGACGTTTGGCGATGGTCGCCTCCGAAGGATTATTAGCCGCGTAATAGTAGATATTTGGAATCTTGCCAATTAAGCTGTCGGGATAGCATTCTCCCGACATCCCCATCTGCTTCCCTGGCATAAATTCCAAGGACCCATGAGTGCCAAAGTGAAGCACCGCATCAGCACCCCAAATTTGCTCTAAATAGGTGTAGTAAGCGGCAAATCCATGATGGGGACTAGCCGATCGCGAGAACAACAACCGCATCGGGTCGCCTTCATACCCAAAGGTTGGCTGAATCCCGATAAAGACGTTTCCAAATGACTTCCCATACACCAACAAATTTTGGCCATCGGTGTTGAGATGTCCCGGAGGCGGTCCCCAGTTTTCTTGCAGGCGTTCAGAATAGGGTGTCAGTTTTTCATACTCTTCCACCGACATCCGATAGGCGACATTCAATTCCGGGCTATTGTACTGCGCTTGGGCATCGTGGATAACTTCCAACATCAGCGCCTCAGCAGACTCAGGCAACTCAGGAAGGTCATACCCGTTGCATTTGAGGGCGTTCATCACTTCATAGATGCTGCCGAACACATCTAGATAGGCAGCAGTTCCCACATTCCCTTTATCTGGGGGGAAACTGAAGATGGTGATAGCCAGTTTTTTATCCAGTTTGGGCTTCCGGCGCAGGGTTGCCCATTTAATTGCCCGTTGGGTGACTGTTTCGATGCGGTCCTGGAGGGCGATCGCCTTCCCGGTAGCCCCATCTCGTCCCGATAAAATAATCGGTTCGATCGCCCCATCCAATTCCGGAATCGCAATCTGTAGGGCCACTTGAATCGGGTGTAACCCCAAATCACTATCCTGCCATTCTTCGGTAGTTTGGAACACCAACGGCAAGGCTACCATATAGGGCCGATTTAACCGTTTCAGAGAGTCGATCGCCTTGGGATGGTCTTGACGGGCGGGACCTCCCACCAAAGCAAATCCGGTCAACGAAATCACCGTATCCACCAACGGCAACGGTTCAACGCCTTTCGCCCCCACATCCCAGAAATAGGCATCCACAGGTTTAGAAAAGTCTAATCCCCCGGCAAACACCGGAATCGGGCGTGCACCCAAGGCTTCAATTTCCTGCACCATTGCCACATAATGGGCATCATCCCCGGTCACCAGGTGGGTGCGTTGCAGCACTAATCCAATGCAGGGGGCCAGGGGGTCTTTGAGGTCATCGGAAATATCGTCCCGGCTGTTATACCAGTTCAGATAATCCTTAACATCCTCAAACATTTTCGGGGCCAAGGGATGCCAGACCCCCATATCCAGATAAACCACTGGATCCTGGAATTTCACCGTTTGCTGACCTTTGAAGACATATTTATCCGCCAACATCAGCAGGAAGTTTTCCAGGTTTTCTGAGGACCCTCCCAACCAATATTGGAAACTCAGCATGAAGTTGCGGGCATCCTGGGCTTTGTCCATCGGTAGATATTTGAGGACTTTGGGCAAGGTTTGTAGCAACTTGAGCATTCCATCCTGGAAGGAACTCCCAGATTTTTCCTTGCGCTTCTTCATAAATTGCCCGATCGCACTCTTGGATTGACCCAATTGCGCCATCGAGAAACTGCCCATTTTATTCAGACGCATCACCTCCGGCATGGAGGGAAACACCACGGCGACATCCAGGCGATCGCGGTGGGGCTCGACTGCGGCAGTCACTTTTTGGGCTAAATCTTCAATGAAAATTAGGGAAGCAATAAAAACATTTGCCGTGGCTAGATCCTGCTTAAAAGCCTCGTAGTTATTCGAGTCACGCAGTTCTTCGATCAAGTAACCACTGATTTCAATGGCTAAATTTTGGTTATTTTCGTTGATTGAGCGAACCGCAGACGATAAAGCACTCTGATACTGGGCTTCTAGCACGACATAGACCACCTTCAGTAAAGAACGCCCTCTGATATCATCTGGGGCAATGTGTCGAATGGTGGGCTTGACGTGAGTGAACATGAAGTTTGGCTCCTTTTAGATGCGCTTGCAGCAATTTAGCAGTCAGGTTTGTCGCGTCGAATTTAGGGTCTAGCGAGTCCAACGCAACAGTGGCAACTGTAAGAGTTTTTACCAAAAAATGCGTCTCTCTGGGGGCTTTTGGCCCAGATCCGACACAATTCGATAAGAAACGATTGCCAATTGTGTAGTTTTGTTAACTTTATTAGCCGGTATTTACTTTACCATGTCCGTTACATAAGTTCATAATTTGCTCTAATATCATCCGTTTCTATTTTTGATTTAACAGATTAGTGATAAATTATTACAGAAACGTAATTAAGCGACGAGCAGGTCTAGGCGATCGGTCACAAAAGAGAGAAGAGTGAGAATTCCTGGACCGAAGGGGTAAGTGAGGGGAACCCCTCTAAATCTTCACAGTGTTCCAATCCCCAACTCTCCCCTTTTCACTCAATCCAAAGGGATTGGGGACCCTCTTAAACCGCCCCAGATTCATCTTCTTAAAAGAATAAACAAAAACTCGATCCAAAATGAAACAATTAAGGTATAATGCTCGGCATATCCGTCAACAACTGACGGGTCAAAATTTTCTGGTGTGAGGAAATTCCAATGAGCTTTGCGGTTTACAACGAAAGTTTTTACTTGACGAATAATCCGGATATTCAACAAGCGGTTAATACCGGAATCTTTACCTCCGGTCTGAGCCACTTCCAAATATTTGGGTTGGGGGAAGGAAGAGTCCAAGTTTCTCCATTTTATGACGAAGCAACCTATTTACTCAACAATCCCGATGTTGCAGCAGCGGTGAGTAATCGATCGCTAACTTCTGGATTGCAACACTTCATTGCTTTAGGGGAAGCCGAAGGACGGGTGAATATTTCCCCATTGTGGAATGAGAACACCTATTTATCTCTAAATCCCGATGTAGCAGGGGCCGTGAATAGTGGACTTTTGGTCTCGGGATTGCAACATTTTCTCGCCCTGGGACAAGCGGAAGGACGTCCCGGTGCACCCCCAGTGTCCCTCACCCCTGCCGGGTTTAACGAATCCGCGTATTTAGCCATCAATACCGATGTCAGAACCGCAGTAGAGTCCGGGGTCCTCAGTTCTGGATTAGCCCACTATCAAAGTTTTGGACAATTTGAACCCAATCGGGCCGGGGTTTTCCTCGGTACCAGTGGGAGTGATACGATTAATGCGTTTGGACAAGCGACAGGCATTCTCGGTGTGGGACTGTCTAATATTACCCCATTGGGGATTGGGGGACTCGATGGAATTCCTACCAGTTTAGGAGTTGGAGAAATTGACACCTTAATTGGAGGACCGGGAGTCGATATTTTTAATCTGGGAATCGGGATTACTCCGTTAAAACCCAACCCACAAAAATTGTATGTGGGACTGGGAAATCTGGACTATGGCCTGATTAAAAACTTTCAGCTAGAGCAAGATTTAATTCTGCTAGCGGGGGAACCGAGGGAGTATCGGTTTGATGCTGCCGATGGAAATTTCCTAATCTCTACCGCAGGCGGTGATTTAGTTGGGATTGTGGAAGGAGTCCCCAATCTACAAATTAGAAATGTTTTTGATGATGGCACCTTTATCCTATCCGGTGGAGAAGGGTCTGTAATCACCGAAGTTCCGGGGTTCAACGATAGCGTTTATTTAGCGGTTAATCGGGATGTAGCAGCGGCAGTGGAAGCCGGAGTTTTCCCCTCGGGATTAGCCCATTATCAAGCATTTGGCCAGAATGAAGGCCGAGTTGGGGTGTTTACCGGGTCCAGTGGCAGCGATGAAATTACGGGATTTGGTCCGAATACCAGTCTGGTGGGAGTCGCAGTCTCGGTGGTGGCGGATTCGCCCAACCAAGATGTGGTGATTACCAGTCAGGGAACGGGTCAGGTTGATGTGTTAGTCGGCGGTCCTGGGGTTGATACATTTATCCTGGGTACGGGGATTAGTTTTGCAAATTCGGTGATTCAACCGTTCTATATCGGGAATGGAAATGAAGATTATGCCTTGATTCGCAACTTTGAACCCGGAAAGGATCAGATTCAGTTGGGGGGGAATCCAGAGGAATATACTTTCCAAGTAGCCGATGGTAATTTCAACATTTTCCGCAATCCCGGTGATTTAGTCGGAATTGTGGAGGGAGTGACCAATATAGCGGTCTTACAAACGTTTACAACGGGACGATTCTTGATGAGTTAGACCCGGAGTCGGGATAGATATCTGTGATCAGAAACCGGATGGCGATCGCCATCCGGTTTTGGTTGAGGGAGAATGCCTGTTAGGTGCGATCGCGCGCTTGTTTAATCACGTCCACAATCTTAGGATGGCCTTCCTCCGCCGCCCAAACCAACGCCGTCCAGTTATTCCGGTCCTTCATCCGAATATCTGCACCGCAGTCGATTAAACATTGTACCACGGCTTCATGTCCATTTCCGGCTGCCGTAATTAAAGCCGTCACCCCAAACTCACTTTGGGCATTGATATCTGCACCCGCAGCAATTAACGCCTCGACCACCTCCACTTTACCCGAACCAGACGCACTCATCAAGGCCGTCCAACCATCATTATCGGCATTTTTAGCCTCTGCACCGGCATCAAGCAATAATTGCACCAATTCCAGATTACCACTCTCCGCAGCAGCGGTTAAAGCGGTTAATCCATCGGCATCTTTTTGATTCACGTCAGCATTTCCCTGGAGTAACGCCTCCACCTGAGATTTTTCTCCGGTTTTAATCGCCTCGATTAACTCAGTCATCCCTGATCTCCTCTGTGATTATAAGGTGATTAACTACCCACAACGTCTGATATTCTATAGTGAATGGTTTACAATTGGCGGATACCATTGAGGGGGTAGGCTTTTCCAGTCAGGGCATCAAATGCCCATGCCTGGATTTTTAAAGGGCCGGGGGGGAGCGTATTGGCGGAAAAATGCGTTTGCCAACCCAACCATAATTGTTCCCTCAGTTGTCGTTGTTGATTGACATCATTTCGTTGCACTCTCACATCGGCGATCGCAAAACCAATGGCGCGCTGGTTGTCATCTTGATAGGTCAAAATCACTGCATCTGCCGCTTGATTTCGTTCCGGTAAAATTGCCCAACCAGAAGCGCGATAAACCCGCTCATCCACCTGTTCCAGACTATCGAACCAACCCGAATCCGCTCCCACTGGAAGGGTTCCAGCAATTTGACTGATATCTTTGCTTTTCACTAAGCCCAGATCCAGGAAACCCAGTTGATCGAGTCGAGTTACGATGCGAGCGAATTTTGCTTTGACTCTCTCTTGCTTCTCGGGGGAGAAGCTATCAAGGGGAACGGGAAACACTCGCTCAAACAAACACTTTTGAGTATCGATCGCCTGACTTAATAGCAAACAGGCTTTTGCTTGCAGGCGATCGCGCCGCATCACACTCATCTGTTCGATTGCCGCAAGGGAAGTGAACAGATGCAAGCCGATCAGTGCAGTTGCCAGAGAAGCAGCAAACCCGGTGGTGAATAATTTCCGGGGAAGAAATACGCCATTTCGGTTAACATGAGCCAAGAGAATGGGAATTAAATGAACCAGCGCAATCAGCAGATAAACCGAGAATGTGGTGTATCGAGAAGCTAAAGCCCCATCGATGCCAAATCCCACGCGCCCCAAGGAAGTGAGCGCGCCACTCATTCCGCTATAAGCGGCGATCGCCAACCAACCCTTAGCGCGATCGAGCAACTCTCCATCTTGACAAATTACCAGATAACCACAGGCTGCGATCGATATCAACAGAATTGCCAATCCTACCCCGGTTGCCACTATTAAACTGTGGGAGGGATTCACTTGTGCCAGAGGCGCACCTAGAAACCCTAGAAAAAAATGAAACGTTTCCCCAGGATGTTGAATTGCATAGGAAAAACGGGGGTGATGGTTCGGCTTCTCATACTGATAAAAATATAGACCTAAGTTCGCCGCAAAAAATGCCACCCATGCAACGATCCACCATTTTTTACGGATAATTTCACGATGTGATCGGGCAAATGCCAACACAGGTAATACCACAATCCACAATAGCATTCCATTGGCAAACGAAAAGGTGCTGATGGTACAAAGCGCCGTACAAATTGTGAATTTAGTAAACTGACTGAGCTTGGAGTGCGCCACCCCGATGCAAGTCGTCAAACAAGCAATAGGAAGGAAAACCACCACTTGAATCCCCCACAACCAATTTTCGTATTGAATGGGAGAAAAAATCAGCAGGTTGGCGAGAAAGGCGATAAAAAGGGATTGGGCTAAGGGTCGGTTGACGGTGATGCGATTTAAGCGATAGAGGTTGGCCGAAACCACAGCAGCTAAGAAGAGACTGACTAGCATTTCCACCCGCACATCCCAGCGAGTTAAATAAGCGAGGGACAGAAAAATAAGTCGGGGGAAAAACTTCCGGCTTTCATTATGTTGGGCAATTAAATCGCCAAGGGATAAGGTATTCTCCGAGAACTGTTCGATGGTTAATCCGGCATTAAACCATTGGTCAGCAAAGGGAACGTTAATGCTATAATTGATGATGAGAATGGTCACAAAAACCGCAGGAACTATAGCTAAGGCGGCTCCCGCGCTCTCTGCACCCTGACTGATTCTTTTCTGCATATCTGCTGATTTTATTTGAGTTACTTTGTAGATGGGGTAAAACGGGATTAAATACCCAGACACAATTAGTGAAACAGGTTTATTACTATTAATTAGTCAACTACCCACCTCAAGTCATGAAAGAGTTTTCCAGGAGAGAGAAATAGAGCCTTTTCTGTGGCTAAAACTTGACGAAATGACAAGTTTTAGTAGGGATGAGTTAGGCAAATCTTTAGATCGACCACTTAATTTAATATAGAAGCAATTCCCTTGCTCATCCATAACAAACGAATTCGGTGATGCGTAAGTTTTTGTAAAATCCTCCCCAGTGTGATTGGCCTAGCGATCAATTCTAAAATTTGGTTCATCTTGAAAGCCAATTTGTTGTTTTATCACATAGTAAGGACGTTGTTTGACTTCATCATAAATGCGAGCGATGTATTCACCGATAATTCCCAAAAAGATAAGCTGCACGCCCCCCATAAAAAAGGTGGTAGTCAACCCAAAAGCCCAGGAGAGAAACTCTCGATTCAAGACTAATTTATAATACAATGCAATCGTCCCAATCGCAAACGAAAAGGTAGCGCAGGCAAAGCCGAACAACGTTGCTAGTCGCAGCGGAATTGTGGAAAAGGCAAAAATGCTATCAAACGTCAGCTTAAACAACTTCCACAGCGTCACCCTGGGTTTACCGCGATAGCGATAACCACGCTCCACAATCACCCCAACTTGCTTAAATCCAGCATAAGCCCGCAACCCGCTGATATATTTATTACGTTCCGGCATTTGGCGCAAAGTGAGAATGACTTGGCGATCCATCAGAGAAAAAATTCCCGCATCCAAGGGAACGAAAATGTCAGATAAAACGCGGTGGATCCGATAAAAACTTTTGAATGCCAGACGTTTGAGCCAACTTTCCTTGCGTTGCTTGCGAATGGCATAAACGACTTCATAGCCTTGTTTCCAGGCACTCACGAATTGGAAAATCGCTTCAGGAGGGTCTTGCAAATCCCCATCCATGAGAATCACCGCCTGCCCCTCGGCGCGATCGATACCCGCTGACAAAGCACATTGATGGCCAAAATTTCTGGACAGGGCGATAATTTTGACATGAGGAGAGTCCTGAGCGATAGTTGTGAGAAGGCTGAGGGAGGCATCCCGACTCCCATCATCTACAAAAATGACTTCTGTATAACCCCCCAGTTCCTTGATGACGGGGGCGAGGCGTTGCCAGAGTTCCGGGATAATAGATTCTTCGTTGAAAATCGGGATAACAACGGAATAATCTATTTTGGACACCATGCTGCTCAATTTATATGCTCCACAATACGAATAAAAGAACCCGTCAGATGCGTTATGCCACATTCCTTGCAGGGCGACTGCACCCATTCTTGCCCCTCAACACCCACCCTAGCGGGTCGATCGCTCATATCGGGCTTGTTTGAGCAATTCCACCACATCTTTAGCTTTTCTTCCGATGCCCAAAGCAACACCGTCCAATTATTGTTATCTTTAGGGCGGATATGGGCACCGCGATCAGGAATTGTACCACGGGCACGAGACCGTTACCTGCCTCCGTCATCAACGGCGTTAAACCAAAATTGGTTTTCGCATTGACATCGGCACCTGCCTCCGTTAGCATTTTTACGATCATCGTTTTTAGCGTCTGCAATTCCATCTAAAATTTAAAATCTCAAATCTAACCTAAAAATAATACAGCCCGTTGAGTGGCGATCGCAACTGCCGACCCGAGACATGATCGCCGATGCACTCGTGCCACAATCGCGATCGCGATTTGTAGTAGCCCGTATAAGCGTATTGGAGAGGATTTACGCATTCACAGGATCTGTAGGGAGTAGAGCAATGCCCACCCTACCCTAGAGTTAAAGTGGTTAGCCTTTAACCCTACATTCCGCAGGTAAAATAAGAGAGGCCCTAGCCCCAGCCAAAAAGTCGATTAAACATCAATAATACAAGAATGGAACCCGTTGATATTGTAATTTTGTCCAATGGTCCTGGAGAATTAGCCACCTGGGTGCGTCCCGTCGTTCGCGCCTTGCAACAACAACTGGGCGATCGCCAAGCAGAAGTGCGGATTTCCCTGATTCTGTCCCCTTGTCCCCATGCTACGGGAAAAGAAGGGGCGATCGCCCGGTCCTATCCAGAAATCGACCGAGTACAGGAAGCACAACACTTTTGGCCCTTTCTACTCCGGGGAAAAACTGCCGACAATTGGGACTGGCGAGAAAAAGGGGTCGTCCTCTTCCTCGGGGGTGACCAATTTTTTACCCTAATCCTCGGCAAACGCTTGGGGTATCGGACGGTAATCTATGCTGAACGGGAAGCGCGCTGGCAACAGTGGATTGACCGTTTTGCCGTGATGAATAGTCAGGTGCAACCCCAGGATTCCCAGAAATATGGTCATAAGTTTACCATAGTCGGGGATTTAATTGCCGATGTTGCCGGGAATGGGGGAAACGAAGAGGAGGAAACAGGAGAATGGGGTGAGGCAGGGGAACTGATTGGACTGCTGCCTGGATCGAAACCGGCGAAACTGATGCAGGGAGTTCCTTTGTGTCTGGCGATCGCTGAATGTATCCATCAAGTGCGACCCCAGACTCAATTTGTGATACCCGTTGCGCCAACTTTAGAGATAGAAACTTTAGCCGAATTTGCCAATCCGCAACAGAATGCGGTCCTGGAATTAGTGAATGGCATAGCTGGGGAATTAAAACGAAACGAGAACAACGATAGGGCGTATTTGGAAACCGCCAGTGGATTGAGAGTGCAACTTTGGAGGCGATCGCCCGCTTATGACCTCCTCTCCCAATGTACCCTCTGCCTCACCACCGTCGGTGCCAACACCGCCGAACTCGGTTCCCTCGGCATCCCCATGATCGTCCTCATCCCCACCCAACAACTAGATGCCATGCGCGCCTGGGATGGATTGCCCGGAATTTTAGCCAACCTCCCCCTATTCGGCACAATCTTTGCCAAACTGATTAACCGCCTCGTCTTACGCCAAGGCAAACTCTTCGCATGGCCCAACATTTGGGCAAACAGCGAAATCGTCCCCGAACTCGTCGGCAAATTGCAACCCCAACAAGTCGCCGAAATTGCCATAGATTGGCTAGAAAACCCCCAAAAACTACAACTCATCCGAGATAAATTACAGTCAGTCCGAGGACAACCCGGTGCCGCCCATCACATCGCTCAAATCATCATAGAAGAGATCAACAACCAATTCAATTAACCTAAAACCTACCGGGGCAATTCGCAACTTGCCCCCTATTTTTCATCTACAAAACAGACTTAAGCTATCTCCAAAATTTCTGAAAAACATAACAAAACTCCCTTGCCACTCTTTTAATCTTATTGTATAATCAAAGAACATACGCTTCAAGAACATCAGGAGGAATCAGGGTGAATACCCCTAACGCCAACTATGACCAAACTTGGAAAGAAGCCTTAGAAGACTATCTCGAACCCTTCATGGCCTTCTTTTTCCCAGAAGTTCATAATCTCATCGATTGGAGCCGAGGATACGAATCCCTAGACAAAGAACTGCAACAAATTACCCCCACCGCCACCAGTGGAGAAAGAGAAGCGGATAAACTCTTCAAAGTCTGGCAAAAAAACGGAGAAGAAGCCTATATCTTGATTCATATCGAAGTCCAGAGTCAAGAAGAGTCAGTTTTTCCCGAACGGATGTACATCTACCATTATCGGTCCTTTGACATCCACAAAAAAGTGATTAGCCTAGCCATCCTAGGAGACGATCGCCCGTCATGGCGGCCCAACTCCTACAGCTATGAACTCGGAGGCAGTTCCGTCAGCTTTAAATTTCCCATCGCCAAACTCCTGGACTATGAAAGCCAATGGGAGACCCTTAAAACCAGTCTCAATCCCTTAGCCTTTTTAGTCATGGCCCATTTAAAAACCCAAGCCAGCACAGGAAAAGCCGAAGAACGGGAACAGTATAAATGGGAGTTAGTACAGAACCTCTCCGAACGAGGTTATAGTGAAAAGGACATCATCAAGCTATTTCGATTACTAGACTGGATGATGACCTTGCCCGAAAGCCTGCAACAAAGTTTTGACACCAAACTCAAAAACTATCAGGAGGAACAAAAAATGCCGATTCTGAGCAACATGGAACGTCGCGCCCTGGAAACGGGTTTCCAAAAAGGTATCCAAACCGCTCGTCGGGAGATGATTTTGGAAGTCTTGAACGCGCGGTTTAACCCAGTGCCAGCCGAGGTGATTGACCGGATTAATCAAATCTCTGATTATGAGACTTTACAGCAACTGCTCACACGGGGGATTTCTATCGGGTCCCTGGCGGAATTTGAGGAAGTTCTTGCCTCGATAATGACTGACAATTAAATCCTTAATCTATGGGAAAGGATAGGGCAGGGCCTTGTCCTTTCTTTCGGTTACGAAACTAGACAGAACACTCACGGGGAGGAAAATATGCCGATTCTGAGCCATGTCGAACGTCGCGCAATGGAAGCCGTTTGCAAAGAATTTTTCCCAGAAGGTATCCCAGAAAGTTTCCCAGAAGATTTCCAAGACGCTTTACAACAAGCTTTCCACAAAGGGTATCAACAAGGTCTCCAAGAAGGTCTCCAATTTGTTCGGGAGATTGTTTTGGAAGTTTTGAACGAGCGGTTTAACCCACTGCCAGCCGAGGTGATTGACCGGATTAATCAAATCTCTGATTATGAGACTTTAAAGCAAGTGTTCAAACAGAGGAGGTCTATCGGCTCGGTTGCGGAATTTGAGCAAGTTCTTGCTGAGCTAATGACTGACAATTAAATCCTTAATCTATGGGAAAGGATAGGGCAGGGCCTTGTCCTTTCCCATAGATTACGAAACTAAACAGAAAACTCCCAGGGAGGGAAATATGCCGATTCTTAGCAATATCGAACGTCGCGCCCTGGAAACTGGTCGCCACGAAGGTCGTCGGGAGATTGTTTTGGAAGTTTTGAACGATCGCTTTAACCCAGTGCCACTGGCAGTGATTGACCGGATTAATCAAATCTCTGATTTGGCGACTTTAAAACAACTGCTCAAACGGGGAATATCTATCGGGTCCCTGGCGGAATTTGAGGAAGTTCTGGAATCCATGCGGACTCACGATTAAAGATTCACGCCATCTGCCGGGACAGGGTGGGGTCTTATCCTTGGGGATGAAATGGGGGACAAACTGCACTACAATCAGGGAAAATGATGTGAAGCCGGGAAATATCAGTCCCGGGCCTGCACGGAATCCAGGCCAACTCCCTGGGAAAGAGCAGAAACTCGATCGCACAACCCGACCAACCCCGTTCCGGGAATCAATCACCGATTAATCAAGGGTAGGCAAGATGAACGAACTAAGGAAAATCGCCTATATAAAACTGATTCAATCCCTCCTGAGTTGTCCCAGTGGCAAGCAGGTCAAGATATTGAGCGCCCACCCGGAACTCATCGATGAGGGTTTGGTGGAGATGATGCGAGTAGTAGCAGAAATGACGGGAGAACAGGGACAGAGGAATGCAGGCTGGTTGCGGAATTTGGCGGGGAAAATAGAAACTGCTAACTATTCCCTACCTCGACTACAAACTAAACTGGCAGCAGATACTCTGTTACAGCAAGGGCTCCAACAGTATCAACAAAGTCAATATCCCCGAGCTTTTCAATCTTTGCAACGGTGCCTTGCATTGTATCAAACAATCGGGGATAAGGCTCGCATGGCAACCGCTTGGAGAGTCTTGGGAGATATCGAGCAACGTCGGGGCAACTGGGATGAGGCGGAGCGTCTGTTTCGGCAATCTTTGCAATTGAGTACCGAATTGGGCGATCGCTGCGGGATGGCAACCTCTTGGGGACAGTTGGGAGATATCGAGCAACGTCGGGGCAACTGGGATGAGGCGGAGCGTCTGTTTCGGCAATCTTTGCAATTGAGTACCGAATTGGGCGATCGCAAAGGCATCGCAACCTCTTGGAGAGTCTTGGGAGATATCGAGCAACGTCGGGGCAATTGGGATGAGGCGGAGCGTCTGTATCAGCAATCTTTGGAATTGAGAATCGAATTGGACGATCGCTCCGGTATGGCAAGCTCTTGGGCAAGTTTGGGAGATATCCAGCGAAATTGGGGCAACTGGGATGAGGCGGAGCGTCTGTATCAGCAATCTTTGGCATTGAGAATCGAATTGGACGATCGCTCCGGTATGGCAAGCTCTTGGGCAAGTTTGGGAGATATCCAGCGAAATTGGGGCAACTGGGATGAGGCGGATCATCTGTATCGGCAATCTTTGAAATTGAGTACCAAATTGGGCGAGCGCTCCTCTATCGCAAACTCTTGGGGACAGTTGGGAAATATTGAGAAACTTCGGGGCAACTGGGATGAGGCGGAGCGTCTGTTTCGGCAATCTTTGGAATTGAGTACCGAATTGGGCGAGCCCTTCTCTATGGCAAACTCTTGGGGACAGTTGGGAGATATCCAGCGATTTCGGGGCAACTGGGATGAGGCGGAGCATCTGTATCGGCAATATTTAGAAGTGATGACCAAATTGGGCGAGCGCTTCGGTATAGCAACCTCTTGGGGAGTCTTAGGAAATATTGAGAAACTTCGGGGCAACTGGGATGAGGCAGAGCGTCTGTTTCGGCAATCTTTGGAATTGAGTACCAACTTGGGCGAGCGCTCCCGTATGGCAACCGCTTGGGGAGAGTTGGGAGATATCGAGAAACTTCGGGGCAACTGGGATGAGGCGGAGCGTCTGTTTCGGCAATCTTTGGAATTGAGTACCAACTTGGGTGATAAATCTGGTATGGGCGACAGTTACAATGATCTGGCAATTGTCCATACACACTTCAACCAAATTCCCGAAGCGATCGCCGCTTGGAGAAAGGGTTTAGCCGTTTGTCCCCCAAACAGATTCCCCCTAGAAGCCTTAGAACTCGGTCGCAGTTTGGGCAATACTGCTTTTGATATCGAAGAGTGGGAAACCGCCATCGAAGGCTATGAGGCTGCCATTGAAGCGGTAGAAACCCTTTGCAGCTTCACCGACTCTTATACCGAAAAACAAAAACGCCGGGAAGCGGAAATCAGTGTTTATGAGAAACTGGTGCAAGCCTGTATCCATGCGGAAGAAATCGGCAAAGCCTTAGCCAGTGTGGAACGGAGCAAGTCTCGCAATCTCATCGAACTGCTTGTCAATGCCAATCTTGAACCCACAGGTAACATTCCTGAAGAAATGCGCCAGGAACTCGATCGCCTGCGTCGGGAAGTCACTGCCAAACAACGCATCCTGGAAAGTCTTGACAACCCCCTCAACTCCAACCTTGTCTCGGATACGGATTTCGGGCAACGGCGAAGTGAGAGTCCCAATTTCAACCCCACGGCTATTGAAACCATTCGTGAACAATACATCGCAGCGAAACAAGCGTTAAACGCACTGCTCGATCGCCTCAAAGCCTACGACCCCAATTTTACCCTGACCCAGCGCGTTGAACCTATCCAATTTTCAGAGATTCAGGGCTTAATCGACGAGAAAACCGCCCTGATTGAATGGTATCTCACTCGCGATCGCATTTATGCGTTTGTGGTGACGGGAGGAGATGGCAAGATCTCCCACTGGGAATCCACCCCGACACAGTACACCGACTTACAGCAGTTGTGCCAAACCTATCTGGATGCCTATTTCAGCAACAAATCCCAGTGGAAAACCGATCTCGATGGCTTCTTGCAGCGTCTCTCGGATATCCTGGATTTACCCCAACTGATTGCCCGGATTCCCTCGGACTACCGTCAACTGATTTTAATTCCCTATCGCGATTTGCACCTGTTTCCCCTGCACGCTTTAGCCATCAACCGCGCCACCGCACCCCACTATTTATGCGATCGCTTTCCCGATGGCGTCAAATATGCCCCCAGTTGTCAATTTTTGCAAGTCTCCCAGCGCAACCAAAAAAGCGAGAGTCAAAACCGCTTTTTTGCTATCCAAAATCCCACAGGAGATTTAACCTACGCAGACTTAGAAGTTGAGGCAATTTTCCCTGCCTTTCACCCCAATGCAAGCTGTCTCACCCGCCAACAAGCCACCAAACTCGCCCTCAGCCAACATCCTTACGAGGCAGATTTTCGTTCCGCCGAATATCTCCATTTTGCCGGACATGGTGGCTTTAATTTTACCAATCCCCTGGACTCATTTCTCGTGCTTGCCGGTGCAGTCGCCGGGGGAGAAAACAATTCCGGGCGTGATCCCGAGCGATTTGTTTCCTGGCGCAAAGGAGAAAGTGTTGAGTTAGAAAAATGTTACACCCTGGGAGAATTGTTCGAGTTGAATTTACCTTACTGTCGCCTCGTCATTCTCTCCGCCTGCGAAACTGGCTTAATAGGGGTTTCTCCCGATTTAGAAGAATACATGAGTTTGGGGTTAGGTTTCCTCTATGCGGGAGCACAAAATGTGATTTGTAGTCTTTGGGCGGTGAATGATTTATCCACGGCGATTTTAATGGTAAAATTATATGAGGAACTGCAAACCCAGTCCTCGGTTTCTCAGGCATTGAACCAAGCGCAGCAGTGGATGAGAAGTGTCACCAAACGGGCATTAATTCAATGGTTGGATGAGTTATCCTTAGAAAAGGAGGTGAAAGATAGTCTGCGTAAAAATTTACCACGGTTAGGCTTGAAGCCTCCGGAGTATCGACCTTTTGAAGATCGGCACCATTGGGCGGCATTTTGCGCGATTGGGATTTAATTTTTGGGGTTAAAATTAAGGGGGAGAAAAATACAGCATTGAGGAGGACATGGCAGTACCCTGTCCCTACGGAAGATAAAACATAATTTCAGGGAATGATTATGAAAGAATCGACGGAAACTTTTCTGATGTTGGCGCAACTCCTGGAAACGGAACCGCCTATTTTGCAACGGGAGGCGCTGTCTCAAGTGCAGCAGTTAGCTGAACAATTAGATCGAGTTCCCGAAGGGGACGAAGAAAAGGCTGCTGCTGTAATTATAGACTGGAGCGCTCAATTTCCGCAAGAGCAAGAAACCTTGGAGAAAGCAGTGTCAAAAGCAGGGTTAAAAAAAGAGCGGAAAGAACTTGATGAAATTTTGGAAAATCACCCCAGGTATGGACAGTGGATTGTTCCGAATTTTGAAATTATCGAAGAACCTGAAACTCAAAGAGATCTGGTTATTATTACTCCCGAGCCACCGCAAAAGCAAACTCCTGCTAAAATGTCCCCGCTTCTCTACCTTCGCCAAAGTTTACAACAATGGATTCACAAGAATCAATAACACCGCTAGTTTATGCGCCGAATTTACATTTATTTGCCTTTCATCTCTGCCGGGGATTAACGGGTGAACCGGATTCCCAAGTGCGGGATCCACAATTGTTGTGGGAACGGGCTGATGCGATGTTGGAAACATTAGGGTTTTCGGAACGCCTCCACCTCTACGGTTATTCTACACCCTCACCGGAACCTCCCGGAACCGAAGTCAATCTGCATCCGAATAACCAACTCAAGTTACAGAGAAAATTTCCTAACTCGGAGTTAGAAATAACCGGCAGAATGCTGGCTTATCGGCTTTATGATAGTTATAGTTTAATCGTTAATTTCCGTCGCCCGGAACGAGAAAAGGGCGAAAAAACGTCTGAAGTGCCTATCTCTATTTGGCGCGATTGGACTAGCGAAAAGGGAATATTTCTGCCCGATTTCGTGCAAAGTTCATTAGGACAAACCCTAGTTTTGACGGCTTTTTTGTCGAAAGAAGACACAGATAAATCTCCTGAAGAGTTGGAAGAATTTGCCTATCGCTGTTTAAGGCAGTTGATTCCCGCTAAAAAAGACCGTCCGCCTTTGGAACGAGTGGGGGAAGTGTTTGGTAGCCCGATTTTTGAATTTGGCGGTCAAATTCTCGACTCGCATCTACAAGAGGAACCGGATCCAAACTGTCACGTTTTAGTTTGGTTGTTTCGCGAAGATTTACCCAGCGCCAAGTTTATCGATTCCTATCGCCAGTTTATCGATTTATTTTACTACCGCAATAAAGCCCTATCCGCTTATCGCGAAACCCGCACCCTTTATCGAAAAATTTACGATGTTTATACAGAACTAGAGAAAAATGTCAAAGATTTTAAGAGGGAATTATTAAAGCAGCCAACCCCAAACCAACGGTTGAGTGAAGCGCAATTAGAGCCACTCAAAGAAGTCTTAAAAAATTTGTCGCAATTGGATTTAGAATATGCGCGGCTGTTGCGAAATTACAAGCATAACCGCAATACAATAGCAATCCATGCCAAAAACTACACCGTTATCTTAGAGAACATCCTTCGCAAGCTCAAGGAAGAAAAACATCCTGTGCAACGGGAGGAACTCGACTTTTTCCGGGAGTTTTGCGATCGCACCTGTCCCTATTTTCAAACCCGCATCGCTGACGAACTCAACTATTTTATCGAGGGTTCCAGTTTGGCAGATAAGGCGATCGCCTCGATTCGCGGTATTGTCGAAATTGAACAAACTCAACTCGATCGCCTGCGCCAAGACCAAGAAAAACAGATCGAAAATACTATCCAAGCCATTGGACTGGCGGTGGGGACTGGGGCGATTTTTGCCTCAAGTGCGGGATTAATCGACCGCCGTTGGCGGATGCCGTGGGCAAGCGATCGCTCGTCTTATCCCCATCCCTTTCTGATTGCTGTTTTCGGCAGTTTTCTCCTGGCGGGCATCGTTTACAAAGTGGTCAAATGCTGTCAAAATCGGGGACATAAAACTCGGAAAAATTAGCCCAGGATAGTCATAAATTGGGGAAGTGAGGGACCCTCATCCCCCGGCCCCTTCTCCCAAAATGGGAGAAGGGGAGCCGGATTTGAAGATTCAACGTCCCTGTCCCAACCCTTCGACTTAGCTCAGGGGGAGAGGGATTTAGGGTGAGGGCAGTAGATTGGAAAAAAGTCTACTTTAATCCTACTCATAGCCCTACCCTTACCAAGGGAAAGGGACCCCGGAACCCCACCCTTTAGGATGCGGGTTTGTATAGACTTGGCAAACTGAACTCAAATGAGATAAAATTACAATTCACATTGCCCAATTTTCTAGGAGGTTTTTAGATTGGTACGAGTACGAGTCCGACAGCACGTTAATCCCCTCAGTTATGCTTATCAAACCCCAATCGTTCCCCCAACGTGGTCACAAATCTATACCAATTCTGCCCAACCTTTGCATTTAGATATTGGCTGTGCTTGGGGGCGATTTTTATTACAAATGGCTCCAATTGAACCCGAGTGGAATTTTCTGGGAGTGGAGATTCGCGAACCTTTAGTGGAAGGGGCTCTGGCTGAACGGGATGAACAGCAATTTAGCAATTTACATTTTATTTTTTGCAATATAAATCACGCTTTTGCTCCGTTGCTGGATAGTTTACCCCCGGGGGTTTTACATCGGGTTTCTATCCAATTTCCCGACCCTTGGTTTAAAAAGCGCCATCAAAAACGGCGCGTGGTGCAACCGGAATTAGTGGAGAAGGTGGCGAAGTATCTCGTGCCGGGAGGGATGGTTTTTTTGCAATCTGATGTGCATGAGGTGGCGGTAGAAATGCGCGATCGCTTTGCAGAACATCCCAGCTTTGCACGGCAAGGGTCAGAGGAGTGGTTACCGGAAAATCCTCTGCCGGTGGCAACGGAACGAGAACAATCAACCCTAGAGAAAAATGAACCTGTTTATCGAGTAGTCTTTCTCAAAACTAGGGAAATTCCAGGATAACTCGGGTAAAAGTATGGGGGATTGCAGTATGGGATGGGGCGGTCCTTTACACTGGAGGCTAATTTTCTTTCCTTGAGGAGCACTACAGAAGATGAATCCAGACGATCGCCCCAATCCAATTCCCCCCCAGGGAAATCCGGGTTTCCGCGTTGCTGTTGCCCGATTTTTCAAGTTTCAGGAACATCAGACGAACTTTCGCACGGAAATCATTGCTGGGGTCACGACGTTTATGACGATGGCTTATATATTAGCCGTGAATCCAGGGATTTTATCTAATGCGATATTTTTAGAGAATTCTGGGGATTTATTTGGGGAGTTAGTCATTGCTACGGCACTCTCTTCGGCGATCGCCACGTTAGTGATGGCAGTGACAGCAAATTATCCTTTTGCTCTCGCACCGGGGATGGGATTGAATGCTTTTTTTGCCTTTTCTGTTGTCATTGGATTAGGCATTGAGTGGCGGGTTGCTCTAGGTGCGATTTTTATTGAAGGAATTTTATTTATTCTCCTTACTCTCTCTCAGGTGCGAAACAAAATTATTCAAGGGATTCCAGAATGCCTGAAGCAAGCAACTGCTGCGGGCATTGGCTTCTTTTTAGCCTATATTGCCCTGTCTGGAGATCCGGCAACGGGAGGGGCGGGAATTATTGTGGCGAACCCGGTGACGATTACGGGGTTGGGAAATTTTCAGGAACCCGCAACGTTAATGGCGATCGCCGGAATTGTGATTACCAGTGCAGCAGTGGCGCGGCGGATTACTGGGGCGCTGTTGTGGGGGATTCTGGCAACGGCTATCCTGGGTTGGATTTTGGGAATTGCCCCGTCTCCCCAGGGAATTGTCGCGTTTCCTGAGTTTCCCACACATTTGTTCGGACAGGCGATCGGGGGTTTGGCAGGGATTCGGGCGAGCAATCTCTGGGATTTTATTGCGGTTACTTTTGTTTTTTTGTTTGTGGATTTGTTTGATACAATTGGTACATTGGCGGGGGTGGGTGTCCAGGGGGGATATATTCGGGAAAATGGAGAACTGCCTCGGGCGACGGAAGCGTTGATGGCGGATGCGATCGGCACGACGGCGGGGGCGATCCTGGGAACTTCTACGGTGACAACCTATATTGAGTCGGCAGCAGGGGTGGCAGAAGGGGGTCGCACAGGGTTTACTGGGGTGACTATTGCGTTGTGCTTTGTTTTATCTATTTTTTTTATACCTTTGTTACAGGCGGTTCCGGGGTTTGCCACGGCTCCAGCTTTAGTGATGGTGGGGGTGTTGATGGCGGGAAATGTGAGGCGGATTCGGTGGGATGACCCGGCGGAGTCGATTCCTTCGTTTTTGACGATTTTGGTGATGCCGTTGAGCTTTTCGATCGCGGAAGGATTAGCAGTGGGGGCGATCGCCTATCCCTTGATCAAGACGTTTCAAGGAAAAGCCCGAGACACTGATCTCACTCAATGGATTTTAGCTGGTATTTTTGTCTTGCGGTTTGTTTATATGGCAGTGACTCCCTAGCTTGGTCAGTCCCTCAAGGGAATGATTTTTGAGCTTGATTTATTGAGGGGCTACCGCCCCTTGACTGACGCCCCCTGAGTGGGTAATAATGTCTTCCGAGAGAGGAATATTGTCCTAAAAATGCTTTAAAATCCGTCATTAGATAGATGCAACCTATCCAACCACTACGAATGAACTCCTCACAGACTCTTGTGACTCAGGAATCCCTCGAATCAAGAGATTAAACTAGACTTTAGATAAGTAAATTAACTCAGAAAATGTTTTGTTTATTCTTGGTGAAGATTCAATCTTAAATCGTTCAAAAGTTGAAGAGGTAGATCTCCCCGGAGGTAGAGGTATTTAAGGAACAATTCTACTTAAAATGAGAGCGTAAACACGAATGCAGGATACATTTTTATCATGGCTTTAGTGAAAATTCACGATTTTTATCCCAACTATCGAGACGAAATTTTTGGCGGCACAGATATCAAAGGAATGGATATCTATGCCGGTACAACCGATGAGAAAGTCGGAACGGTTTACGATATTCTGTTAGATGACACGGGCCGTTTCCGTTATCTGGTGGTTGATACCGGATTCTGGATATTCGGGAAAAAAGTGCTGCTTCCCATCGGGTCGGCTCGGATTGATTACGATGCTGGACGAATTTATGCGATCGGCTTAGTGGACAAAAATCAAGCCGAACAGTTGCCCGAATATGACGAACTGCAACCGATCGATTACGAGTATGAAGAGCGTGTACGTGATGTCTACCGCGATCGCACTGCGGTAACCGACACAGCAGCAGCGACTCCGGCAGCATCCACGACTGCTACCCGCAATCGCGATACCTACCACTACGATCAAGAGCCTCATCTTTACGATCGCAACGATACCGACCACCGCAATCTCAAACTGTATGAAGAACGCTTGATTGCCAACAAAGACCGTTACAAAGCCGGAGAAGTTGCTGTCGGTAAACAGGTAGAAACCGAAGTCGCTCGCGCTGCGGTTCCCGTAGAGAAAGAGCGCGTGGTGATTGAACGCACCAGTGCTGGCATGAGCGACGCCCAGGCTGTGGCTCCCGGAACTGCCAATTTCCAAGAAGGCGAAGTGGCACGAGCCGAAGTCTACGAAGAGACCGCTGACATCCATAAAGAAGCCTTTGTCCGCGAAAATGTCGAAATCCATAAGGAAGTCGAACGCGACATGGTAGAAGGCCAAGAAACCCTTCGTCGGGAAGAATTAAAAGTGGATACCGACGGTAAACCTGTGGTGGAACGACGCCCCCGTAAGTAATATCTTCTCGCTTCTGGATCTAACAACCAACGGGCGCGGGTAAAATCTCGGCCCGACCCCCTAAACCGGGGAATCGGGCCGCTACCTTATCCGAACAAGTGCTGGTTGAATGAAACAGAATCCCATCACCAGGGTGCCTCATCTAACCTGAGTCAAGAGCCAAACAGACCAAGGCTTTTGGCTCAGGTACAATGACTAAAATTTGTTTTAAATTTCCGTCAATTTTTTTCAAATAACACTAAAAGGAACAGTCAAGTTATGAATGATCAACTAAGGGAGAGAGGGGATAACGGGGGTTATGCTCAGACTGAGGGCGAACTTCCGGCTCGATTGGATAACCTCAAGAGTCAACTGGTCAATTTTACAGTTCGAGATTCCGAAGGGCAACCCCTGGGTCGAGTCATGGATTTAACCATAGAACCAGAGAACCAACTCAATTTAATTGTGTCCCTGGTAGACGATCGCCCGGGTCGGTTGGTGAAAGTGAGTAGCGATTTGTTTGAAAAAATAGAATATGCGACGAATACAGTTTTTGTCTTACTGACCCGACAACACTTTGCCGCCCTACCAGAATATCAAACCCCGGCTTACTCTGGCGAAATTGATCCATCGGAGTTACCGGGAGAGTGGGTAGAGTCTGTTCCCTCTGCTGGGAGTTCAGGGACGATCGCCCTTGAGCAGCGATCGCATCAAATCGATTCCCAGAGTTCTTTAGCGGACTTTAAGCAAATCCGCAAGGAAGTGATTGCCAGTAACATTCCCTTACACGAAGAACGATTAGTGGTGAATCGCCACAAGCGCAAAGTCGGTGAGGTGGTCGTCCGGAAAGAAATTGAAACTCGGATGATCCAAGTTCCCATCCGTCGGGAAAAGTTAATTGTTGAGCAAGTCAGTCCCGAGTATAAAAAACTCACGGAAATTATTTTAGGGGAGGGAGATGGGTATCGCCTAGGGTCCGATGAAGCGCCAGGAATTACGCCTACTACCGCGTCACTCATGCCGCAAGGGCAAGGAACGAACCGAGTTAGCGGAGAATTTCACTCTCCTGAAATTGCTGCTCGAATTTTAGAAGAAATTTCCAAGCGACAACCGAACGGTTGTGTAAAAGTGCGGGTTGAACTAGTGGTGGAAGAGGAACGGTTTCGCAATACCTATCAGTCTTGGTTTGATCGCTATTCTACGCCGCAATCGTGAATTTTAGGGAGTGAGTGATATCCTGTTTGCTTGATTATACGGAGGGACCTAACCCCCCAACCCCCTTCCCTAAGAGGGAAGGGGGAGAAGAAAGAGGGAGGGAGAAAGGAAGGGAGAAAGGGAGGAAGGGAGGAAGAAATGGTTTTTTAATACCAAATCTGGTTGTTAAAAGTCCGTTTTCTCTTCAGCCCGCGCAGGCGGGCTTTGTTCGTATAGCCCCAGGCTTGAGCCTGTGGGTTTTTATTGATACTAAAGAACTGGCGGGGGGTTGAACCTCCGCCGGTTTTTTGTGGGGGGGAATTGAGAAGTAAGATTAACCGGGTTCGTCGGTAGAATGATGATAAGCGATGATGCGATCGCGACCGGCAGTCTTGGCTTGATAGAGGGCTTGATCTGCACAACGATACAACATATCTACCGTTTTGCCATCTTCGGGATACTGAGCAACCCCGCCACTAAAGGTCAGGTATAAACGCTCCTCCCCGATTATCAAGGGTTCCGCATGGAGGATTTGGAGTAACTCACTCAGGCGTTTTGACCCGGACTCTTTGTTCATGCCATACATTCCCACTACAAATTCTTCCCCACCCCAACGAGCGACGATATCCTCACTGCGAAAGGTCCGAAGCAAGAGTTTACCGAATTGCCGCAGCACGGCATCTCCCATCGCATGACCGTGGCGATCGTTGACTTGCTTAAAGCGATCGAGGTCTACCATCGACAGACACATCGGTTGTTCATTCAGTTGGCACAGGTGCAGGAACTTGTCGAATTCGGTGATGGATTTGCGCCGGTTGGCCACTCCGGTCAGGGGGTCAGTTTCTGCCATGTTTCGCAGTAACTGAATGCGTTCGAGACGGTTGAGAATGCGGGTAACCAGTTCCGGGCCGACAATGGGTTTACTAATATAATCATCAGCACCGGCAGCAAACACTTGATGGACGATATCCGGCCCTGTGTGAGCGGTCAAAAATAAGACCGGCAGACTGTTCCATCGTGGGTCGTTGCGAACCACTTGACAAAGTTCAATGCCGTTGAGATGGGGTAATTCGATGTCGAGAATTAGCAGATCCGGGGATGACACTTCTAGGGTTTCCCAGAAGCGCTGGGAGTCAGAGAGGGCAATGGTTTTCATGCCCCAAGGTTCGAGGAAATGTTTGACGAGGGAGAGGATTTGTGGGTCATCATCCACGACCATGATTTTAGCCTCCGTCGTCTGAACTCCCTGCAAAATTTGTAATACCGCTTCCATGATTTGAGCGGGTCTCACAGGTTTTTGTAAAAAAGCACGGCCTCCCAATCGAGCAACTTCTAATCGGTCTTCTACTCGACTTTGGTCGGTAACAACCAGAACCGGGAGGGGTGGGAACCCATTGGCGAGTTCTGAGAGTAAGGTTAATCCTTCTTCTTTATTATTGGGGTTGATAGTGAGGGTCTCTTCGGTCGATAAATCTAATAAGACGGCATCGGGACGGCGATGGGCGATCGCCGTTCTGGCAGAGGAAATCGAGTCACTATTGACCACCTTGATTCCCCACCCTTTGACCTCAACGCCGATCTGGTGGGAGAGTTCCTGATCTCCCTCAATCATCAGGAGCACCGGCAGATCGTTAAGTGGACTTCCCTCCCGGCGATCGCTCTTGACGGGCGCTTGGTCAATCTGCGATCGCAGGGCCTGAACTAATCCCGTGAGATTCCCACATTGGGTGGCATCGAGAGTGGGACTGTGCAACAACTGTTCCACTTGCCGCGCAATCACTGAACCTTCCGTCAATCCAAAAGTCCCTAAAGACCCCGCCAATTTGTGCGCTTCCTGTTTTGCCGTAGCGTGCAATTCTGGCGGCAGTTCGCCATAATTCAGGGCCTCAGTTGCCTGCTCGATCGCCGTTACTCGTTCCGCAATCCGGTCTTTGAACCGTTCCCAGACTTTGCCAATGGCGGCGACAATGGTCGGGTCCTGTTTGGCAGAGGGTTGGGGGTCTGATAAGTTCAGATTCAGGAGTTTGGCCACTTCACGAGCGAGTTCCTCCCCATCCAGGGGGTGATAAAGAAAGCAGGTGACCCGATCTAGGGTTTCCGATTGCTGTTTTGTGGTTGAGCTATTCCGGGGTTCTTTCGGTTTTCTTCCTTTACCTGATGGGGCGATGGGGTAGGTTTCTATCCCTTTTACGCCACAGTAAATCACCGGAATCGGGGGGGAGGATTGTCCTTTATTGCCGATTTGTTTGAGCAGTTCTGCCGGGGAGGGATGGCGCAAATGTTCATCTAAAATGACCAAGGACCATTGGCGATCGCGCAATTCCGTTCGAGTATCTTCTCCCGTGTGGGTCACCCGGACCACCGCATTGCCTAGGGCGTCGGTTCAGTACCCGAGCTTGACAAAATAACTGGACTATGCCTAACTGAAATTGACGACCCGATTAAATTCAAGCCCTCATTACGGTATAAAGTCTATGCGTCCTCCTTTGTGGCACCCGCCAGTAGAGCTATCAGATTCAGAACAGGTAATTATTAATCGCATCAAAAAAGCCAAGCTTTTTACTTTTCTTCGCCTGAACCGTCTGTTCATATTCGATGATGAGTTTCAAGAAGAACTAAACACCATTTTTAAAGACAGTACAATGGGCAACTGTCCCGTCGCACCAGCCCAATTGGCCTTAGCCACTATTCTCCAAGCTTATATGGGTATTTCTGACGAGGAAGTGATTGAAGAGCTAGTCATGGACCTACGATGGCAATTAGCTCTGAATTGTCTGAACTGCGAAAAACCCCCATTCAGTAAAGCCACTTTAATAAGATTCAGAAGCGCCTTAATTAAAAAAGGCTTTGACCAACGTTTAATTGACCGGACTGTAGACATTGCCAAGCTCAAAGGAGGTTTTGGTTCGGCTAACTTAAGAGCTGCATTAGATTCCTCTCCTTTATGGGGTGCAGGTAAAGTTGAAGATACCTATAATCTCTTGGGTCATGCTCTGCGTAAGGCATTGAGCATAATAGCTAGTCAGCAGGGGTGGGGGCTGGCAGAAATTGCCAATGAAGCGGGAGCGGATTTTGTCAATAGTTCCAGCTTAAAAGCCGCATTAGATTTAAATTGGGATGACCCAGCCGAAAGCCAAAAGGCATTATCAACCATACTAAAGAGCCTCAATTCTGTAGAAGAATGGATACAACAGCAGTCTAATCCTGATGAAATAGAAGAGGCACAAGCTCCTCTCCAGGTTGCCCGATTGATTGAATCCCAAAATGTGACATTAGACACAATGGGAGTGCCGAAGCTGGCCAAAGGGGTTGCTAAGGACCGACGCATTTCCATTGAAGACCCAGATATGCGGCATGGCCGAAAAAGCCGTTCTCAAAAAATAAATGGTTATAAACGCCATATTCTTAAAGATTTAGATATAGGGGTAATTCGGGCTGTGGCTGTAACCCGTGCTAATACACCAGAAGCTGCTGCCACTGTTGACTTAGAAGTTGACTTAAAAAGACAACAGGTTCAGTTAAATGAACTCCATATCGACCGAGCTTATTTATCGAGTCATTGGGTAAAAGAACGCTCCGAACAATTACAGATATTTTGTAAAGCGTGGCCGGTAAGAAACTCAGGACGATTTGATAAAAACGCCTTTGTTTTTGACTGGGATAACCAGGTAATTAGTTGTCCAAATCAAGTTATTATGCCGTTTGAACCCGGTAAGATCGTTCATTTTCCTAAACCGGAGTGTGCTGCTTGTCCCCTGAGAGAACGCTGTACTACGAGTAAGAATGGCCGCAGCATATCTATCCATCCCGATGAAGGATTGATGCAGGAATTACGTCAGCGTCAATCTACCTCAAGCGGTCGCGCTCAACTGAGGGAGAGAACGTCTGTAGAACACTCTCTGGCTCATGTCGGACAGTGGCAGGACAAACGTGCCCGTTATATTGGACAGCGCAAAAACCTCTTCGACCTCAGACGAGTGGCTGTTGTCCATAATCTTCATGTCATTGCTCGAATGAATGAGGTTTTACCAATACAACAGGCCGCACTGTAGTTGAGTCCAGCAGGTAGATTCACATTTGCTTGGTTTTGTCAAGCCCTTTTACTGAACCGACGCCCTAGGCGCTGTTGCAACCAAAATCCCAACTCATCCGGCAACCCCGCCATCAGGATCCGAGGCGGTTGCACCAATTTCTCCTCCTGAATCGGTTTGAGTCGATACCCTAACCCATAGACGGTTTCGATCGCATCTGCCGGAGCCCCACTGGATTTAAGTTTTTGCCGCAACCCTTTGATATGGGCGCGAATCGTATCTTCCGAGGGGGGTTCATCAAAAGACCATAAATGATCCAGAATTGCACTGCGACTATAAACCCGGCTGCTGTTTCGCATAAACAGTTCCAACAGCCGATATTCCGTCGGGGTCAAAGTGACGGGTTGGTTGTGATAAGTAACGTCACAGGTACTCGGATTAAGTTGTAATGCTCCCCACTCTAAAACCGGGGGTAATGGCGCTGTCCCCCGGCGTAATAAGGCCCGAATTCGGGCGGTGAGTTCCGGTAAGTCGAAGGGTTTGACGAGATAATCATCGGCACCGGCATCAAGTCCTTTAACTTTATCTTCTGTGCTGTCTTTCGCCGTGAGCAATAGGATGGGCATTTGATAGCCACAACTGCGTAACTTCCGGCATAAACTAATTCCATCCAGTTTCGGAAGCATGACATCGAGCAACAGCAGGTCATAGTCACAGGCTTGAGCTAATTCTAATCCTAGCAGCCCATCTGTTGCCACATCCACAACATGATTTTGCTGCTTTAATGTAGCTACAAGTGCTTGAGCGATCGGTTCGTCATCCTCCACCAGTAAAATTCTCATAGTAGTTTATTGTAAGGGTATGAATTGGACTCCTGATGAGTCAGCCGCCTAAAAACGTATCTATTGTTAAGTCTGGGGTTCTTTTCTGAAATTTGGAGTGAAAATTGGCGGTCAATGAACCTGCCTGCCAAAGGGGCTGAGAATAAAAAGTCTTGACGGGAGGTTCTTCAGTGACCAGGGATCACAGCGTTAAGTTGAGGGATCACAATTGTCACAGACCGTTCAAGGCTGGGGCGCTTCTCAAGTTTTACCTCAGAATGTTTAATCTCTTCCTTTCATTCCTCCAGAAAGATTACCTGTGTTTCAATTATAAACTCAAGTCGCATCGTTTATGTAAATTACGGACACAAAATCTATCCCAAGTATCACTAGGTTTTCGAGTAAACACGAGATGAAACAGCCCATTTAAAGTGGAAATTACGGAGAGATTTTCAGGGATCAGTTTAGGGTAATTTAGCCGTTTCCATTCCTCAGCCTAGGGTTGTTCCTTTTCTTTGAAGGCGATCGCCCGTTTTCTCCCCCGGACAGAGTTCAGCCCTCGGGGTGAAATTACTAAGTATTAATCAGGAAAGTTCATAATTATTAACGCTTCACCTAGTCTGGCAAGGGTTGATTTTCACCTCAAAATATAGATTAATCTCCATTAGGCGCAGTTAGACTGAATGGGTAAATCCAGCAACAGTGACCCTGGTAGACATTATTTCCTTCATTTTAAGGCGCTTTCTCGTATTTTATTCTTAAACAATATTAGGGGTTACGTTAAAAAAATTAACAAAACTCACTCCAGAACTGAACGGGAAAGCAGCCCTGACCGATAGTGCTATCTACAAGAGTTTATCTTTTATCTTATCAGATCTCCGTGAGGGTACTCCAATCGGTCCGGGTATCCTGTTCAGCATTCCGGTCAACTTGATGTAGCAACACCGAAGTTGGGACATCCACCCAAAATGCCTGGATGAGGATTGGATTGGGGAATGACCATTCTGGGCAATGATGGGATCCGGTGGAGTCTCTTAATCGGCTTCAACAGATCAGACGAGGCGATCGCCACTCTGTCCAGAGAGAGTAGACCTTTTCGGGCCAGACTGAATTTCCCGACCCGCCCAGAAAAGCGTTATAATATCGCCGTTGACACCCAAGAACGTTGAAATCATCTGCTCATCAATATAATAACCCTCCCACTCCTATGATTTTGAACGTTAATGTCATCACTCCCTCAAAAACCATCTGGAATGCTCCCAGTTCCGAGGTAATTTTGCCCACAAGTACAGGTCAAATCGGGATTTTATCGGGTCATGTAGCATTGGTTACCTTTATTAAAGTCGGGGTCATGAGAATCCGCTATCAAAACACTTGGATTCCGATTTTTGTGAAGGGAGGATTTGCAGAAATTGAAGGGGATATTGTGACCGTTTTAGTCAATGATGCTGAACGGGGCGATCGCATTGACCCCGAAATAGCTCATTCCGAGTTAGAGAAAGCGCAGGCACAGTTATCTCAAGCCTCAAATTCCCTAGAAAAAATCCGCGCCCAACTTTTTCTAAAACAAGCGCGTGCCCGGGATACTGCCGCTAGAGAGTTCCCTGATTCATTACAACTAGATATCCCGGATCCGATTGCTGCAAAAAATGCAGCCGTTTCCGCTTTGAAGGTGATTGAACAGTTATAAAGGCTTTCAAGAAACCTAGGATTTATAGGAAAAATATAGGGGAGGAGTTCAATTTTGGAAAGAGACCTCTCCCCGGCCCTCTCCTAAGAGGAGAGGGAGAATAAGGACATTTTTTTATTGCTGTACGGGGCAAATTTACATCTTTCTCCCCCTTCCCTCTTAGGGAAGGGGGCTGGGGGGTTAGGTCTCTTTCCAAAGGGGTATCATCCAGATTTTTGCGAGAATTGGCCCGGTTTTCTAGGGGAATGAGGGCGTTTGCCCAAGGCGATCGCCACGGACCCAGTAACCACTAGCATTGCGCCAATTATCGCTAAAACCGTTAACTGTTCCGGGGCGATCGGCAGGGGAATTCCCAGAGAAATTACCCAGACTGAGAGTAAGGTTACAATGGGCGTTGTTGCCAGAATTGCACTAACTTTAGAGGCATCCCAATGGGCTAAAGATTCCGCAAAAGCGCCGTAGGCTACAACCGTATTTAACCCAGAAAAAATTAACATTCCCCACTCTAACGGAGTCAGGTTTAATAGATTGCTAGGGCTAGAAAAAGGTAGGAATAATAAGGCGCAAATTCCATATAACAACAGCATGATATTAGAAGAGGTCAACTGTTGTAAGAGTTGTTTTTGCGCCAGGGCATAAATCGCCCAAGCTGCTGCTGCGATTACCAGAATGATATTGCCGATTAAATAAGTACGAGGGGCGGCCAGGACGGTTTGTAATTGTTCATGAAAAAACACTACAAAACCCAGGGTTAAGATGCCCAATCCAGCCCATTGGCGCAGGGTATAGCGTTCTTTAAAAATGGCGATCGCCCCTAATCCCATTAACACCGGCGCTAACTGAATAAACACTTGAGCATTGGCAGGAGAAGTTTGGGCTAATCCTTGTAAGTACAAGGCATAATTTACCGACAAAAATCCTGTGGCGACTGCCAGTAATTTCCATGAAGTTCCTCGCAGTTTTTCCAGGGAGGGAAGTTGCTGACGCATCCCTAAAATGCAGACTAATATCCCAAATGACAAGGAAAACCGAAACCAAGTCACGGTGTAAACATCAAGGGCTTGAAGGGTTATTTTCAGGGCGATGGGTAGCACTCCCCATAAGATAACCGTCACCAAGGACAGACCCAACCCCAACCGCCAACGCCCAGAACTCTCATGGAGTTTCATTGGGGATTTAGTCGGCAGGGGAGTGGGTTGATTTTCTAAACTCATTGCGTTGATTTAAACAGGGTAAAAAGATGTCACTCTCCTATTATGCAACATTTTGCCTAATACTAAATCCGGTACTGATAGGTTTGCAAAAACCCGCACCCTGAAGGGTGGGGCTATACGGACAAAGCCTGCCTACGCAGGCTACTCTATAAACATGACTGTTCATACCTGGATTTTTTATTCCTGTCCTAATAAATCGAGTAACTCAGCTTCCGAGAGTTGTTTGATGCCTAAATCTTGGGCTTTTTTTAACTTAGACCCGGCATCTTCTCCAAGGAGTAAGTAATCGGTTTTTGCACTCACTGACCCGGTGACTTTCCCTCCGGCATTTTGAATTAAGGCTTTGGCTTCATCTCGTTTTAGGGTGGGAAGCGTTCCGGTAATCACAAAGGTTTTTCCAGCAAAAATAGCGGCGGATTGACTCGCCGGTTTTTCCGTAACTGGAGTGGCAGCAAATTGTAAACCAGCGGCTTTTAGTCGGTCAATCAAGAGTTGATTAGCCGGAACTTGGAACCAGTCGGCGACGGAATTAGCAATTTCTGCACCAATCCCATAAACGCTTTCAATTTGGGCAGCGGATGCAGCAGATAATTGGTCAACGGTGGGGAATTTTTGGGTTAATAATTGAGCATTCACACTGCCAACGTGGCGAATGCCTAATCCATAGAGGACGCGGGACCAAGGTTTCTGGGTGGATTGGGCGATCGCCTCGACTAATTTCTGGGCGGATTTCTTGCCAAATCTTTCTAATTGAGCTAATGTTTCTACATCCAGTTCGTAGAGTTCTGCGACAGAATTGACGAACTGGCGATCGACGAATTGCTGAACTAGCTTTTCTCCCAATCCGTTAATATCTAAAGCATCCCGACTCCCCCAATGAATTAGAACACCGCGCAAAATTGCGGGACAAGACAAATTGATACAGCGGGTGACTGCTTCTGAAATGGGTTTAACCACAGGTTGTCCGCATTCGGGACAGTGAGTGGGCATTTGGAAGCGTTGAGCACCTTCCGGGCGTAATTCTGGCAGAATCCGGACCACTTCTGGGATGATTTCTCCAGCTTTTCTGACGATCGCCGTGTCTCCGATATGCAAATCTAATTCAGCAAGGCGATCGCTATTATGTAAAGAGGCGCGAGAGACGGTGGTTCCTGCTAATTGGACTGGGGTTAATTCCGCAACGGGAGTTAAGGCCCCCGTGCGTCCGACTTGCACGGTAACGGCTTTAATTTGGGTGGGGGCTTCTTCTGCGGGATATTTCAGTGCGACTGCCCATCGGGGGAATTTTTGAGTAAATCCCAGTTGTTTTTGCAGGGGGATGGAATTAATTTTCACCACCACCCCATCGGTCATGTAAGGCAAATCTTTCCGTTTGATATCCCACTCCTTATAATAGGATTCAACTGCTTCCAAGGATTGACATAAAGTGCGATTGGGATTGACTTTAAACCCCATTTCTTGTAGCAGTTCTAAGGATTGCCATTGGGTATGGGCAACATCATCATCATCTATTCCTGGAATCTGCAAGGTATAAGCAAAAAAGTCTAATCGCCGTTGGGCAACAATCCGGGAATCTAGTTGTCGCAAAGTCCCGGCTGCGGCATTCCGGGGATTAGCAAATTCCGCTTCCCCGGATTGCGCTCTTTCTTTATTGATTTTAGCAAAGACATCTAATCCTAAAAAGGCTTCGCCGCGCACTTCGACTAAGGGGGGCGGGTTTTCTAAATTTAACCGCAAAGGAATCGCCCGAATGGTTCTAACATTTTGGGTGATTTCTTCCCCTTCTATGCCATCGCCTCGGGTTGCGCCTCGAACTAATAAGCCATTTTCATAAGTTAAGGCTAAGGCTGAACCATCAATTTTTAATTCGGTGACATATTCAAAGTTAAGGGGGGAAACAATCCGTTGCCAGCGGTCCTGCCATTGGGAAAATTCCTGAAGATTAAAGGCATTTTCTAAGCTGTACAGGGGAATGTTATGGCGGACCTTTTGAAATTGGGTGGCGGGTTTTTCGCCGACGCGCTGGGTGGGACTGTCTGGGGTGATGAATTGGGGATGTTCTTGTTCGAGTTGTTGCAATTCTCGATAGAGGCGATCGTAAACGCTATCCTCCATGATGGGATTGTCTAGGACATAGTAGGCATAGCTGGCTTTTTGGATTTGTTGGCGGAGTTGTTCGATTCTCTGTTGCAGTTCTAGGGTGGGTTCTGGCATGGGTTTTGTAGGAGTTATTGGTTTTGAGTTAGGGTTGGCAGAAGAGAACGACGGATGTCGTTACTACGAACAATTGGTTTTTGGGGTTAGATGTCCATCTTCCATTGTAAGGATGCGATCGGCATAATGTTCGATGCGGGGGTCGTGGGTGACGACTGCCACGGCTTTTTGATGGGTTTTGGCAACGTTGCTTAATAGCTGGATCACCGATTGTCCCGTTTGATAGTCTAGGCTGCCGGTGGGTTCATCGGCTAAGAGTAAGGCGGGGTCATTAGCGAGGGCGCGGGCGATCGCCACCCGTTGTTTTTCTCCACCACTTAAGGCGGGGGGGAAGAAATTGGCGCGATGGGCGATGTTTAACTCCTCTAATAAAAATTTAGCCCGTTGATGGGCGGCTACTCCGGTTTTTCCTGCTAAATTTAAAATCAGTTTGACGTTTTCGAGAACGGTTAGAAAATTGAGCAGGCGGAAGGTTTGAAAAATAAATCCAATGTTTTTTAATCTAAAGTCCGTGAGAGCAGTTTGGCTCAAACAAGTAACTTCGCAATCCAGAATTTTAATCGTACCTTCTGTTGGTTTTCCCATGCAGCCTAATAACGAGAGGAGGGTGGTTTTGCCACTGCCATTGGGTCCGCTAATCAGGACGAGTTCCCCGGCTTTCAACTCTAGGCTAACATCTTCAACAGCTTGCACGAAATTCAGATTTTTTTGTCCATACATTTTGTACAAATGTTCGGATTTTAAGATGGAATTATTGGGCATAATTAAGCTCTAAATACTTCTGCGGGATAGATATTTTTCAAGGTTCTAATTGGGGCCAATGTGCCAATTGCTCCCAGGATTAAGCACGCGATTAATACTCCAGTCGCATCCTGCCAGGTAAAGACCAATAATAAGGAAGGAATCACTTCAGTGAGCAAGGGGGCAAAGGTAATATCGATAATAAACCCTACGGAAAAGCCCAATAATGCGGCTAACATGGATTGTTTTAAGACGAGGATTCCTAAAAATTTTTGGGATGCGCCGACGGCTTTTAACATGGCATAGTCTTCTCGTTTTTCCAGGACCGAAGTGTACATCATCAGGACAATGACTGTGCCTCCAGTAATCGCGCCAAATAAGACGATAGTCCAGAGAATGGGCAAAACGCCAATTTCCATTTCTTCGACATTATTGGCGGCAAATTCAGCTTGAGGGATAAAGACTAAATCCGGGAATTGAGCTTCTAAGCGGGAGATGATTTCTGGGGAATCTGAATCAAGATTGAGCAGGAAAAAGCTGCGGACATTCTGCAATCCGAGTAAGCGAGGAACATCATCCAGGCGAGTAAAGGCAAATTGACCAACAATTAAGTTCGTGCCTTGGCTAATTCCGACAATTTTAAAGGGATAGCCTTGCAGGGAGAGAGAATCACCCAGCTTGAGGTTATGGGTGGCGGTAAAAGCGCGGTCTAAAATAATTTCTTGGGGTTGGAGAGTGGAGGTTCCGGAACTAATTTCCGGTGCACCGATTTGAGAGTTTGAGTCAAATCCGAAGATATATAAAGTCACCGTTTTATCGGGGAATTCAGCGGGGGCAATGGCGCGTAGGAGACTATCGACGCTTTTGACCCCCTCTACTTGACTCAGGGTATTGCCGAGGGTTTCGGGTAAAAACGAAGAGGTTTTAATTAAATTTCGGGTATTACGTTGGCTGACCCAAACTGATGCTTGAGTATGCAATACATAACTTTTTGACCCAAATTTTACCCCTTGGTAAACCCCGAGTAAAAATAGCATCAACATGACGCTAAAGGCAATCCCCAGAACGGCGATCGCAAAGCGTCCTTTTGCTTCCCAAATCATTCGCAGGGCAACGGGAACCATAAGCGAGTATCCTATCCAATAATCGATGAAGTATTCTTGTTCACCAGTGAAGGCTATAATAACGCGATCGCCTCATTATATTCCGACTTTCTCCCCTTGCACCCCCTCTTGCCCCTCATCTAAACCGGCAAGAACCCCCCTGATCCGAACCCAAACCTTCCGCGATCGCACCGAAATTAAGGGATTGACAGGAATTCAAACTCATGCTTTGACCGGGAATCGCCGCAAACCATTCCGGTTTACTCCAAATCAGTCCAAAATTTCCGGTCGGGAAACGGGTTACAATAAACTTAGCTTGCCTAAATCAAAACATTACACTATTTACGCGAAAGATTTTATCTGTGGAATTGCCAGAAAACGCCGCAAAACAATCGTTTGAGTTTGACTCGATAGAGGAGGCCCTCGCTGAAATTGCAGCAGGACGGTCCATTATTGTGGTCGATGATGAAAACCGGGAAAATGAAGGGGATCTGATCTGTGCGGCTCAGTTTGTGACACCGGAAATCGTTAATTTCATGGCGGTGCATGGTCGCGGGTTAATTTGTCTGGCGATGACCGGCGATCGCCTGGATCAGCTTGACCTCCCCTTAATGGTAACCACCAACACCGACACCAATCAAACCGCTTTCACCGTCAGTATCGATGCCTCTCCTCAGCAAGGAGTCACCACGGGCATTTCTGCTGAGGACCGCGCCCGCACCATCCAGATTGCCATTAATCCCCACACCAAACCCAAGGATTTGCGCCGTCCTGGTCATATTTTTCCCCTGCGGGCCACATCTGGAGGGGTACTGAAACGGGCGGGCCATACGGAAGCGGCAGTAGACTTAAGTCAACTCGCCGGACTCTATCCTGCCGGGGTAATCTGCGAAATACAGAATCCCGATGGCTCAATGGCGCGATTGCCGGAACTGATTGAATATGCCGCCAAATATAACCTGAAAATGATCAGCATCGCGGATTTAATCGCCTATCGCCTCCAACATGAGCGGTTTGTGATTCGGGAAACTGAGGCGGCATTACCCACGGAATTCGGCCAGTTCCGAATCTACGGCTATCGCAATACCCTGGACAATAAAGACCATGTGGCGATCGTCAAGGGAGACCCGGCCAATTTTACCAATAAAGCGGTGATGGTGCGGGTCCATTCGGAATGCTTGACTGGGGATGCCCTCGGTTCTCTGCGCTGTGACTGCCGAATGCAACTCCAAGCTGCCCTAAAAATGATTGAAAATGCCGGGGAGGGTGTGGTGGTCTACCTGCGTCAGGAAGGCCGGGGAATTGGCCTGATTAATAAACTCAAAGCCTATTCTCTGCAAGATATGGGACTGGATACCGTAGAAGCTAATGAACGCTTAGGCTTTCCGGCAGACTTGCGAAACTATGGCGTAGGGGCGCAAATTCTCAATGATTTAGGGGTGAGCAGAATTCGTCTGATTACCAATAATCCGCGTAAAATTGCGGGATTAAAGGGATATGGGTTAGAAATGGTCGATCGCGTTCCTCTACTGATCGAGTCCAATCCGTTTAACTGCACCTATTTGGCAACCAAGGCGGAAAAATTAGGGCATATGCTCTTACAAACCTATTTGGTCACGGTGGCAATCCACTGGCAAGAACCGGAACTGGAAGAGGGTCCTCCGGCCCAAGTTCAAGCCTGGTATGAACATTTAGAAAAAATCCGCGAACTCGCCGATGAGCACCATCTGGTCCTCCAAGAGGAAAAACGCCCGGTCACTGTGGCCTTATTTGGCAAACCCCAGTTAACCTTTCACCTGGGATTTGACCAAGCTCATTTAGCGACAACGGATTGGTTTACCCATCCCGAACATCCTTATGTGCAGGCGACCTTTCGGATTCTCGATCGCCTCCTCCTCTGGCCCGATATTGATCAACTCCAGTTCCTAGTCTCCACCGGGGTCGATCCCTTGACCAATCTCGGGGTGCAACTCCAACGCCAGTCTTTCCCTTTGAGCAAAATGCCGTCGCAACTGTGCGATAGCCTACATACCCAAGTGATCTACTGCTTTAAGGGGTAAGGGTAAAAGGATTCAGAATTAGCCCAGAGAAATCGAGTCGGATTTCACCGGGCAAATGGAAATCAAATGGGGCGGCGATCGGATAGTCGTTGCTACAAGTAGGGGGATAACTCTCCCTCAATTTCTGCGGTGGAGTGAACGGGGTTCAAAATTCTGATCCTCCCCAAAATAAAATCTCTAAAACGTTCGTAGTAGCCCCGTCAATGTAGGGGCGCAATGCTTGCGCCCTCCGGAGGGCGCAAGCATTGCGCCCCTACAGATATGAACGGTTGGATGATTTATATTTTGCAATCCCCTTAACGGAACTCCCCAAAATAAAATCTCTAAAACGTTCGTTCGTAGTGATGGATCAATGGAGTAGCCGCGTCAATGTAGGGGCCTGCGCATTGCGCCCCTACAGATATGAACGGTTGGATGATTTATATTTTGCAATCCCGTAACTCGTGGGAAAGATTTGGGTAAAAATGCACGCTTTTCTTGTTACTTTAAAATTATTAAGTTTTTGAGTAAACTTCCTTTATCGGAATGTAAAGAGTCTCAATGGTGCGACCCATCCCTCGATCGCCGGTTTTCTCCTATAGCGCGGCTGTCTTCACTGTCGTCATTGCCTTACTCCTGACCGTCACCTTCAAACCCATCCTGGCTTCAACCCTGTTTCTGTTCTTTTTTCTAGCCGTAACGGGGATGACTTGGTATGGGGGAATTGGTCCAGGACTAGTGACAACGATACTCTCTGTGTTAGCCCTCGACTATTTTTTCCTGGTTCCCACCCACTCCTTAACGGTACTCAGTGGAACCAACCTGTTGCGAATGGGGTTGTTTGTCTTAGTTACCTTGGCGATCGCCAAGCTGAACACTAAACTCCAGCAGACCAAACGGCAGTTAGAAATTAGCTTGAGTCAGCTAAAGCAGAGTGAGGAACGCTATCGGCGGATTGTCGAAACCGCGTCAGAAGGCATCTGGATTTTGGATGAGGCAGGGCGAACCCGCTATGTGAATCAGCGAATGGCGCAAATGTTGGGCTGTTCTCCAGAGTCCATGCTCGATCGCCCGTTTTTTGAGTGGTTTGACCAAGGCAGTCGCCCCGAGGGATACCAGACCCTGACCCAACCCTATCCCGGATACCCTGAACAATGGGATGGGCGATTTCGCCGTAGTGATCAGTCCCTGCTTTGGGCGATCGTCTCTATGAATTCCATTTTTGATGACCAGGGTCAGTTTCAAGGGACCCATCTGATGCTCACCGATGTTAGCGATCGTCAACAAACCCAGGAACGTCTACAACTTTCTTTAGAAGCAGGACGCATGGGATTTTGGGATTGGAATCTGAGCACCAACGAGATTGTGCGATCGGACAATCTGGCGGAAATTTACGGGGTGAGTCCGGGTCAATTAGAGCAGACATTTGAGAGTTCTTTAAACCTGATTCATCCCGAGGACCGGGAACGAGTCCAGGAGGCGATCGCCCAGGCGGTGGCAGAAAATACCCCCTACAGCTTAGAATTTCGGATTCAGCCCTCCCCGGAAAATATTCGCTGGATCTTAGGCAAAGGACGAGTCTTTAAAGATGCTCAGGGCACAGCAGTCCGGATGATCGGAATTGCGATGGACATCAGCGATCGCAAGCAAACCGAAGAGGTGCTAGGGCAGACTCAACAGCGATTCGAGACCTTTATGAACTATAGTCCCGTTGCCGCTTACTTTAAAGACGAAGCCGGACGCTATATTTATGTCAATCCCATAGTAGAACGGTTGTGGCAGCGCTCCCAGGAGAAATGGGTGGGTCAAACCGACGCGGACCTCTTTCCCGAGGCAGTCGCCCAGGAACTGCAAGCTCATGATGCCACCGTATTAGAAACCGACCAGGCCCTGGAATTTTTAGAAACAGTCGAACACCTCGACGGGAAGCATTATTGGATCTCCTGGAAATTTCCCATGCACGAACCCTCCGGAAGACGATTGCTGGCCGGAATTTCCCTAGATATCACCGATCGCAAGCGCACTCAAGAAGAACGGGATCTGCTGCTGGCGAACCTCGAATCCCAACAAGAACTCCTGAGTGCCGTGTTGCAGCAAATGCCTGCCGGGGCGATCGTCGCTGAGGCCCCCTCCGGGCAGTTAGTCTTAATGAATCAGCAAGTTAGAGAAATTTTAGGCATTTCCCTGACTCCCCTCATCACCATCCCGAGTTATCTCCATACTTCCTATCAAATTTTTCACCCCGACGGTCAACCTTATCACCCAGACGCTTTACCCTTAGCGCGATCCATCTCCCAGGGAGAAGTTGTGGTTGAAGAAGAACTGCAAATCCAACGCGCCGATGGGACCCGGGTCACCGTCCTCGCCAACTCCGGCCCCATTCGCAACGCCGAGGGCGAAATTGTCGCCGCAGTGGTGACCTTTTATGACATCACTGCACAAAAACGCGCCCAAGCTGAAATCAAACGCTATGCCGATGTAGTCAAAAATATTCAAGTCGGCTTAAGTGTCTGGCAACTCACCCCAGGAGAGGAACCCCCTTCCTTTGAGCTAATAAGTGCTAATCCTGCGGCAAGTCAACTGGCGGGAAGAGATTTAGACCGGGCCGTAGGAATGCGGATTGAGACTTTATTTCCCCATCTGGTCAAAACCTCACGAATTGCCGAATTGATAGAGGTTTTGAATAGCTCATCGGCACGGGAGTTTCCCGAAGTTATCTATAACGACGATGCCGGAGAAGAGCGCTGTTGTTCCATGAAAGCCTTTTCCCTACCTAATCGCTGTCTTGGGTTAGCCTATGAAGATATCACCGATCGCAAACAAGCACAATTTGCTTTACTCGAAAGCGAGCAACGGTTTCGGACAATGGCCGATGCTGCGCCGGTTTATATTTGGTTATCGGGAATTGATCAGCTTTGTTATTACTTTAATAAACCCTGGTTGGAGTTTACCGGCAGGACTTTAGAAGAAGAAATTGGCAATGGCTGGACTGAAGGAGTGCATCCAGATGACTTCAAATTTTGCCTTGATACTTATCAAAAATCCTTTGATTTGCGCCAACCCTTTGAGATGGAATATCGCCTGCGCCGTTATGATGGGGAATACCGTTGGGTGTTAGACCGCGCCGTGCCTCGGTTTTCCCCCGATGGCCGATTTGAGGGGTATGTGGGGTCTTGTATTGATATTAGCGATCGCAAACTTTACGAGGGTGAAATTAAGCGTCTCAATGCCAGTCTCGAACGCCGGGTAACCGACCGAACGGCCCAACTGGAAGCTGCCAATCAGGAACTCGAATCCTTTGCTTATTCGGTCTCCCATGATTTGCGTGCCCCCCTACGACATATTAGCGGATTTGTGAATTTGCTCCGCAAACGGATCGAACCCTCTCTGGATGAGAATAGTCAGCGCTATCTTGATATTATTGTTGCTAGTACCCACCAAGCGGAAGAGTTGATTGATAATTTGTTAGCTTTTTCTCGCATGGCCCGCGCTCAGATGCGCTTCATCAAAGTCGATATGAATCAACTGGTGAACGAGGTGCGGCAGACTTTGGAGATCCACAGAGGCGATCGGAAAATCCTCTGGAAGATTGCCTCCTTACCCCCGGTGAAAGGGGAACCCACCATGTTAAGATTAGTCTTTCAAAATCTTCTGGATAATGCGATTAAGTACAGCCAACGACGGGAAACGGCTGAAATCACGGTAGGGTTCAATGAAAGTGACCTCGAATTTATCTTTTTTGTGCGAGATAATGGCATTGGATTTGATATGCGCTACGCTCACAAACTCTTTGGAGTTTTTCAACGCTTGCATAGCAATCCCGATTATGTGGGAACTGGCATCGGACTGGCCAATGTTCGCCGCATTATCCATCGTCACGGAGGTCGCACTTGGGCAGAAGGTGAGGTCGATTTAGGAGCTACATTTTATTTTTCTCTACCTAAACAACCGGAAGGGGATCAAGTGGACGCGAGTCCGAATGTCCTCGGGTCAACCTAATCCTAGTCTGGTTATATGATGTGCAATGAAACAGTTTTTCTGATACGGATTCCGTATAAAACCCTGGACAATAGCTGGATCTGACTCAGTGAAAGGATTGAGGTACAACATCCCATTTTATATAATAAAACACAATCATAGATTATTGTCATCCCCGCAAAATGAGATAAAATTCGAGCGTCATCTACCCATTAAACCCCATGAACCAGGGAGAACCCAGGATGGACATCAAACGCATTCTACTGGTAGAAGATAATGCCAATGATATAGAGCTAATTTTGACGGGACTGGCGGAGAATAACCTAGCCAATGAAGTCATCGTCGTGCGCGATGGGGAAGAAGCGCTAGATTATCTGTTTCGTCGGGGTATCTTTAGATTGAGGCGAGAAGGACATCCCATCCTGGTGATGCTTGACCTCAAACTACCCAAAATCGATGGCCTGGAAGTGCTGGCACAAATGAAGTCTAAGACGGATTTGCGGCAGATTCCCGTGGTGATTTTGACCGCTTCTCGGGAAGAATCGGACCTGATTAGCAGCTACAATTTAGGGGTGAATGGCTATGTCATCAAGCCCTTAGATTTCCATGAGTTTGTGGATGCCATCAAAAGCCTAGGACTATTCTGGGCCGTAGTCAATCAACCGCCTCCAGGCTCTTTGCCTGCTGTAGCGCGAGAATGAGTCACCTAACTAAATGAATGATGGACGGTTAAAGTGCTGCATATCCTACTGCTAGAAGACAGTCTGCTGGATGCAGAGCTAATTGAGGCCCACTTGCTAGAGAGTGGTCTCAATGTGGCATTGAAGCGGGTAGACACCTGCGACGCCTTTCAAAATGCCCTGGAAAGCGGATCGTTTGACGTGATTTTGGCCGATTATTCTCTTCCCTCCTTCGATGGATTTTCCGCCCTGAAAATGGCCCAATTGAGATGTCCGGACCTACCATTTATCTTTGTGTCCGCGACCCTGGGGGAGGAAGTGGCCCTGGAGACTCTGAAAAATGGGGCCACGGATTATGTCCTCAAACAGCGGTTAGAACGACTGGTTCCCTCGGTGCAGCGAGCGATTCGAGAGGCGACAGAACACCGCGATCGCCTAAAAGCTGAAGCGGCCCTTCAAGAGAGCGATCGCCGGTTTAGAATGGCCCTGAAAAATTCATTTATCTGCATTTTTCAACAAGACCGGGACCTGAAATATCAATGGATTCACAATCCCCAGGGACCTGAAACCGCAGAGGAAATCGTCGGAGAAACGGACTATTTCTTATTTTCTGAAGCGGATGCCGACTACCTCAGCACCCTCAAACGAGAGGTGATTGCCACGGGAAGTCCCAATCGGTTTGAAATCTCTGTGACTATTTCGGGCGAAATCCGGGACTATGACCTGATTTTAGAACCTGTATTTGAGGATGAGGAGAATCAGGACAATCCCCAGGTGGTGGCCCTGATGGGGACCGCCTTGAATATTACCGAACGCAAGCGATCGGAACGAGAACTCTATCGTCGGGAACAACAATTTCGAGCTTTAGCCGAAAATGCGCCCGATATTATCGCCCGCTTTGATCAACAACTGCGCCACATTTACATCAATCCGGCGATCGAAAAAGCCACCGGAATCCCTCCGCAGGAGTTTATCGGCAAAACCAATGCAGAGTTAGGATTTCCCGAAGATATTTATTTACAGTGGTCCCGACATTTACAAAATATTTTTGTTACCGGAGAACCCAGTTTTCTAGAATTTGAGTTTCCTTCCTCAACAGGAACCCGGACTTATCAATCCCAGGCTGTTCCAGAATTTGACTTAGAGGGTAATGTCGAGTCTTTACTCTGCATTAGTCGGGATATGACAGAAAGCAAACAAGCCGAACAGGTGCTGCGAGAGAGTGAGGCGCGGTTCCGTCGGTTGATGGATTCCAATACCATTGGCATGGGGTTTTGGCATGGGGAGGCCATTACGGTTGCCAATGATGCTTTTTTGGAAATGATGGGTTACTCCCAGGAGGACTTGCAACGGGAACCGTTGAATTGGCGCGAGATTACCCCCTCGGAATATTTACATCTGGATGCAAACGCCAATCAGCAAGCGCGTCAAACAGGCTATACCGAGCCCTTTGAAAAGGAATTTTTTCACAAAGATGGCACCCGAATTCCGGTGCTTTTGGGAGGGGCGATTTTTGACAATAATGCCGATGCAGGGGTCTTTTTTACCCTGGATTTGACCGAACGCAAACGGATGGAAAAGGCACTACAGCAACAAGCGGAGGCGTTAGAACGAGCCAATCAGGTCAAGGATCAGTTTTTAGCGGTCCTCTCCCATGAGTTGCGATCGCCCCTAAATGCGATTCTCGGATGGTCCCAGTTACTGCTGGCGCGCAAATTTGACGAAGCTACCACGCGCCGCGCTTTGGAGACGATCGAACGCAATGCGCGATTCCAAACCCAACTGATTGAGGATTTGCTAGATGTCTCCCGCATCCTGCGCGGCAAGCTGACCCTGAAAGTCACGCGAGTGAATTTATCGACCCCCATCTGCGCGGCGATCGAAAGTTTGCGTCTGGCGATCGAAGCCAAATCCCTTCAACTGGACTATTCCCCAAATCCCAGTGTCTCCCCAGTAATGGGAGACTCTAACCGCTTGCAGCAAGTGGTATGGAATCTCTTGTCTAATGCGGTGAAATTTACTGAACCCGGGGGTCAAGTCAGTCTGAATCTCAAACAACAGGATCACTGGGTGATTCTGCAAGTCCAGGATACGGGAGTTGGCATTCTACCCGAATTTCTCCCCCATTTATTTGAATATTTCCGCCAAGCGGATGCCTCTAGTACCCGCAATCATGGGGGACTTGGGATTGGATTAGGACTGGTGCGCCATCTGGTGGAACTACATGGGGGAACTGTGAGTGCAGAAAGTCCGGGAGAGGGACAGGGGGCGACTTTCATTGTGAAACTCCCGGCGATCGCCTTCAAAGCTGACCCCAACATCCAATTGCCGCAAGTCTCTCCCAAGCAGAAACTGACGGGAGTGCGGGTCCTGGTTGTGGATGACGATCAGGACTCGTTACAGTTTATGCAGTTTGTCTTAGAACAGTCGGGATGCCAAGTCCGGGCGATCGCCTCCCCCATTGAAGCCCTCGCTGTATTTTCTGACTGGCAACCGGATCTCCTGATTAGCGATATTGCCATGCCAGAAGAGGATGGGTATAGTTTCATCCGCAAAATTCGCGCAATGGAGAGAAACGCCGGAGGACAAATTCCGGCTGTTGCTCTAACAGCTTATGCCCGAGAAGAAGACCGCAATGCTGCATTTTTAGCCGGATTTCAAGAGCATTTAACTAAACCCATTGACCCGAAAGTCTTAATGGCGGCGATCGAATTGTTAACTCGACCTATTGAGTAATTTTAGAAAAGTATCGGGAGATGCGGAGGATGTACAAGAGTAAGTTTTTTCCCCTTAAGTACCCCTCCCCTTGGCAAGGGGAGGGGTACTTAAGGGGATTGCAAAATATAAATCATCCAACCGTTTAACTGAAAGGAAGTGTAGGGGCGCAATGCGCAGGCCCCAGGGGCCTGCGCATTGCGCCCCTACATTGACGGGGCTACTCCGTTGATCTACGAACGAACATTTTGGAGATTTTATTTTTTGGAGTTCCCTCATAGACTCTCCACTCACCCATTGTCCGCGCAAGTGCGATCGCCCAAGAAGAACCCCACCCTAACCCTCCCCTTGGCAAGGGGAGGGGACCGGAGGGGTAGTTAATAGAAAGGTAAATCACCATGAGCTAACCTACTTTTGTAAGCCCCCATTCTCCCCATCCTCCCCTATCTCCTAATGAGAGAGTTTTTCTAGAAAAATCTGTCGATCGTCGCGGTAAATGACTTTGAGTTTTTCCTGGAAAACTGTCATAAAGGCATCAATTCCTCGCCCGGTATTACAGTGCGGGCGATCGGGAAATTCAAAGTGATAGTCATCGAAAATAATCATGCCGCCTTCTTTGATCAGTCCCCAACTTAATACAGCATCTTGGAGGACATCAATGGCAAAATGAGAACCATCAATATAGACGATATGATAGAAATTTAACGGGAGCGATCGCAGCACTTCTTGCGAGAATCCCACCCGTTTATCAACTTTGTGCTTGGCTCCACTTTTTTCGATATTGCCGTCAAATCTCTCTTCTACAGATTTCTGCACCGTCGGGTCATTCTTTTTACTCTCCACCACCCCTTCAAAATTATCAATACAGGTAATCCGGGCAGTTTCATGGGTCAGAATATTATCCAGCAACCAACAACTCGCCATGCCTTCAAAACAGCCCACTTCTACCACTCTCAAGTTCGGCATATTCGCATATTTTCGGAAATTCTGTTCCCAAATGGGCATGACTCCGGTAAAACAGTCGGCGCTGACGTTATAGCCTTTTTGAGCAAATTGGAGAGTATAGGGAATCGTGGAGAGTTTTTTGTGGAGGATTTCGTTATTTGGCTTAAATTCCAGGGCTTTCTTTAAAGCAAGTTCGGCTTGATAAACTTTTTCGACGTTACTGGTAAATAAGCCTTCATAGTACAGGGACATCCCGAGGTTATACTGAGCATGACTAGACCCGGGCTCAAGTTCTACCATTTTCTGGGCGGCATTGGCGGCTTGGGGATATTTGCAATTGGCCCAACTTTTTTCAATGACGCGCTGATAAATGGTTCGCAAAACTTCCTGGGATTGGGGGGTATAAATGGCTGATAAAATATACCGGGCGGAAGCATATTCCGGCTGCTTGTCGGAAATTTGGCTTAAGAGTTCGGCAGCTTCACTCAATTTACCTTGAGCAAAAAATGCCATTGCTAGGGGGTAGGTGATGGAAATTTCTGGAACGAGGTCTTGGGCTTTCCAGAAGGAGAGAATTGCTTCTGGGAATTCTCCATAATCGCAATGTTTCAGGGCTTTATTGCGATAATAATTTCCATAGGTTTGTTGGAGGCGGATATTCTGGTTCCAGTCGGGATGATTTAATAGGTTTTGGGTTACAGCGGCTTCTAATAGTTGGAGGGATTTAACATGAAAGACTTGCCCTTCGGCGAGTTGGCGTAAGACGGCGATGAGCAGGGGTTGGTTGAGGTTAGAATAGTTAGAGGATAATAGTAATTCGGCTGTGGTGATTAACCGTTCGGTGAGGGTGGAGTCGATGAGTCCGAGGTGGAGGTAAAGTTGCAGACGGGCGAGATGGTTATTGATATCATGGGGTGCGATCGCCTCAATGCGATCGCGCAAGACTAAGGCGCTTTCCCAGTCCTTCACGGATTCCCTCTGGTTGGCGATCGCCCCTAAAAGCTGATAAAGCTGCTGTCGCCACTGTTGAACTTGAGGCGGTGTTCCCTGAGAAAATACCGCATTCCAGCAATGTTCCGCTTCCGTTTGCTTTCCTTGCAGTAACAAGGCGACCCCTAAATACCAGTAATTGACAATCACCTGGGGCTGCGCTTGAATGTTTTGTCGGCATAGGGCAACTGCACCCTCATAGTCCTGCTTGGCGAAATATTCCGTAACCATCGGTTGGACTTGCATGATTTCTATTCCTGTCTGTTCTCAATCAAGGGTTCAGATTTCAAAGATGAAAGTTCCCCCATCCCATCGGGATTTTTTGGAGGTCCTTTTGAGGAAAAACGGTGTTCTGGCCTATTTCACGAAACACCCCCTCGGAAAAATGGCCTCTGTGAATTCTGGGCAATTCTCTAGGATACAAAAGAATCCCAAAGAATACAAAAAAAAACCGGGCTTTTTACAAAACCCGGTAGATTCAAACCCTGGATCAGCCCTTAAAACTGTTGCTGCAAAAATTTTTCCAATCTATCCAACCCCTTCTCAATGGTGGGTAAATCCGTGGCATAAGATAAGCGGATACAGTCATCATCCCCGAAGGCAATTCCCGGAATGGCAGCAACCTGGTGAGATTCCAGTAAGGCATCACAGAATTTTAGGGATTTCATCCCGGTTTTAGCAATATTCAGAAACACATAAAAAGCACCTTCGGGTTCGGGACAACTGATGCCGGACATCCCCCGAATTCGGTCCAAAACCGCTACCCGGCGCATTGCAAAGGCTTGAAGCATTTCTTGGACACAATCTTGCTCGGATTCCAAGGCGGCGATCGCCCCATATTGGGCAAAAGTACAGACATTGGAGGTACTGTGACTTTGAATGGTACTCGCTGCCTGGATCAGTTCCTCATCCCCCGCCAAATACCCAATCCGCCACCCGGTCATTGAGTAGGCTTTGGCAAACCCATTACTGATAATCGTGCGTTTGAACACTTCTTCAGAAACCGCGCCGATACTCAAATGTTTGATGTCGTTGTAGAGGATTTTCTCATAAATCTCATCGGAAACCACTAAAATATCCTGCTCAACCACCACCTCAGCTAAGGCGCGAATCTCGTCGGGGGAATAGACCATTCCCGTGGGATTAGACGGTGAATTAAGAATAAACAGCTTGGTTTTCGGCGTACAAGCGCTTCGCAGTTGGTCGGGAGTAATTTTATACCCACTTTCGGCAGTGGTGGAGACGATCACCGGGCTCCCCCCGGCTAAGGTGACCATTTCTGGATAACTCAACCAGAAGGGGGCCGGGATAATTACCTCGTCCCCGGACTCGATGAGGGCCAGCATGAGGTTAAAGAGAGAATGCTTGCCGCCATTGGTGACGATGACATTTTTCGCGGAATAGTCGAGATTGTTATCGGTTTTGAGCTTCTGGGCGATCGCTTCTCGTAACAGGGGTTCACCGGCGGCGGGTCCATATTTGGTTTTTCCGGCATTCAATGCTTTTTCTGCCGCCATTTTGATATGGTTGGGCGTATCAAAATCCGGTTCCCCTGTACTAAAACTACAAACATCTATCCCATCGGCTTTCATCGCCTTAGCTTTGGCGGCGATGGCCAAGGTCAGGGATGGTGTTACCTGTCCAACTCTTGCTGCCAGCTTCATTTGCCTACTTCAACTGAGAATAAATTTAAGGATATGCTTCGCTCAGAATATCCTACTCTACCCTCTCTGAGGCAGGGATGTCAGGCGATCGTGACATCGGAGGACAGATAAACCTCTTGAATGGTATGAAACAATTTGACGCCTTCCTCAAAAGGTCGTTGGAAGGCTTTGCGTCCGGAAATTAACCCACAACCCCCAGCCCGCTTGTTAATCACGGCGGTTCGCACGGCTTGGGCGAAGTCGTTTTCACCGGCAGAACTCCCTCCGGAATTAATCAATCCGGCCCGTCCAGCATAGCAGTTAAGCAGTTGATATCGGGTCATGTCAATGGGATGGTTTGAGCTTAACTCAGTCTCAACTCGCTTATCGGTCCGTCCGTACTTTTGACCCAAGGCTTGGGAAACTGCCCCATATCCGCCATTGCATTCCGGTTGTTTCTGTTTGATGATATCCGCTTGGATGGTAACGCCGAGGTGATTGGCTTGCCCGGTCAGGTCAGCGGCGAGATGATAGTCTTGGTCTTGTTTAAAGGCGCTATTTCGCAGGTAACACCAGAGGATGGTTGCCATGCCATATTCATGGGCTTGAGCAAAGGCGGCGCTGACTTCCTGGATCTGGCGGGTGGATTCCGGGGACCCAAAGTAAATGGTTGCGCCGACGGCAACGGCCCCTAAGTTCCAGGCTTGTTCGACGCTGGCAAACATGATTTGGTCATATTGGTTGGGAACGGTGAGCAGTTCGTTGTGGTTGAGTTTGAGGATAAAGGGGATTTTGTGGGCATATTTGCGGGAGACGCTGCCGAGGACGCCTAGGGTTGTAGCAACGGCGTTACACCCTCCGGCGACTGCTAATTTAATAATGTTTTCGGGATCGAAGTAAATCGGGTTGGGGGCAAAGGAGGCGGCGGCAGAATGTTCGATGCCTTGATCCACGGGGAGAATGGAGAGGTAGCCGGTGTTGGCAAGATTGCCGTGGGAATAGAGTTGCTGGAGCGATCGCAATACGGGCACTGAGCGATCGCTATGGGATGCCACCCGGTCAATCCAATCGGGTCCGGGCAACTGAAACAGTTGTTTGGGAAGTTGGGCCTGATATGTGAGCAAATCTTCCGCTTCATCTCCCAGAATCGAGGCGATCGCTGAAGGGGTTGATAGGGTCGTTGTCATGGTGTTTTACCTCACAATTTTCTAAATTCCACTGTTTCATGATATCGTCCCCCTCTGTAAACTGTTGTCCGATATCATGATTTTAGGCCAATTTTTCTCTTAATCAATTCTCTTTTTTTGCTGCAACTGTAGCAACTTCCCCCCTGCTTTAATCAGAGGATTGAATCAGGGTGATTTATGTCATTAGATAGAAGACATCTCCCCAATCTCTGGGGTAATATTAACCTTATTCCCAAGGGCTAAGGGCTAAACCCACGCAATTCAAAAATATTTGGCCCAGGGAGCAAGTCAAGGAAGGTTAAAAATACTTATGCAAGTACCTGTAGAAATCACTTATCGAAATCTTGAAAAAACTGAGGCGATCGATAACTTAGTTCGGGAAAAAGTTGCCAAACTCGAACAATTTTGCGATCACATCACAAGCTGCCGAGTGGCGGTTGAAAAAAACAATGAGCGCCCCAGTAGTGGTTCTCCCTATCGGGTTCGCTTCGATATCACTGTTCCCCCATCCCATGAAATCGCCGCAGTTTGTAACCCCGGTGAGGGGAATCAGTATGACGAACTTGATACGGTAATTCGCAATGCTTATGAGGCGGCCCGTCGTCAAGTGGTGGAACTGACCCAACGGCAAAATAATAAGGTTAAAGATCATCCCGCGCAAGCAATGGGAGCAGTCGTCTCTCAGCTATTCCCAGAAGACGGTTATGGCTTTATCAAAACCCTGGACAGTGGACGGGAAATCTATTTTCACCGGAACAGTGTTTTAGGCGATCGCTTTGATGAATTAAAAGAAGGCGCAGGGGTACATTTTTCCGAAACTCAAGGAGAAATGGGTCCTCAAGCAACCACTGTTCATCTGGTCAATAAACTCGGTCCAAATGAGGCAACAGAGCAACAGTCTAACATCGAACAACCCATTGGTTGGAAATAATTATAGAGTTCTGGACTCCTGGGGTACAGATTCCGATCAGGAGTGCGAGCATCTTGCTCGCTAAGGGGATTGCAAAATATAAATCCTGCAAACGTTCAACTAAAAGGAAGGTATATGTAGGGGCGCAATGCTTGCCCCCTCCGGAGGGCCTGCGCATTGCGCCCCTACATTGACGGGGGTTTGTTCCGTTGAGCCGTCACTACGAACGAACGTTTTGAAGATTTTATTTTTTGGAGTTCCCTAAATGTAGAGGCTATTCGCGAATCGCCTTTACATTTAGGGCTTAAGGCTAAAAATGGCGTAAGTCCCATTAGATAAAAACAGTAAACGATAAATCAGGAGAAGACAATGGCTTTAGCATTACAAACAAGGGCAATTGGTGTATTTGAAGATAGCCAAACTACAGAAAATGCCTTGAATGCCCTCGGTGAGGCAGGCTTTTTAATGGACAATATCTTAGTCGCCACCCAAGATAATATCCCCGATGAAATGGAGAGTCCCGATAGTGAATTTTTAGAGAATCGCACCGTTGAAGGCTTAGGAAAGGGGGTCATGAATGGAACCGTTTTCGGGGCGATCGCCGGTTTATTTAGTGGCCTCACCACCTTATTTCTGCCTGGACTCGGCCCGATCGCCGTCGTCGGTCCCGTCGCCACTGTTGCCGGTTTGACCGCCGCAGGCAGCTTTTATGGGGCCCTAGGGGGGGCGATCGTCGGGACGGTTGCTGGAGACAAATTTACCGAAGGTCAAGCCAATATTTATCATCAACATTTGACCCAAGGACATTATTTAGTTCGCCTAGAAGGGACCGAGGAACAAATCACCCAAGCTGAATCCATTTTGAGGGAGCATGGCATTCAAGAGTGGCAAATTTATCAATCCACCGACAATTAAAAGAATTGAATTATATCAAATTTTCTTCAAATTATTGTCCCCTGTTTTGTTCCTACAAACCCAGATTTTCTGGGTTTGTTTGCTCTATCAAAAGTCGAATAAAAACAGAGGATGGAATTAATTAATCTCCCTCACCTGGTAGAGGATAAAATCTCAAATTTGCCTCACTATGTTAAGTAATTGAAAAAGATTAAATTCAAAGGAGAATATCCAATGAGCAGCACCACAATAAATAATATGAAGAAAATTCTCGGTATAAGTGCCGCCGTATCATTAGGCGCAACGGTACTTCCCGCGACTTCGATCGCTGCCCCAGAGGGTGCGTCTCTTGACATCGCCCAAGCTCAACCCGCGCAAGCCGCACCAGCGTGCCGCGAAGTGGAGGCAGAACCCGGTTTAAACGTTCGCGCCCAGCCCTGGGGAGAGGTGATCGGAAGTGTGGGAACTAACGAATATGTCTATCTGCAAAACCCTGCCCCTCAAGATCAGGATTGGGTACAAATTCAATCCCCAATGAATGGCTATGTAGCAGCTAACTATCTTAGCTACTGTACAGGAGCAGCAGCTCAACAGCAACCTCTAACTGGAGTTGACCCACAAGGACCGATTAGTCAACAACCGGGTCAGATGCAACCAGGTCAGATGCAACCGGGTCAGATGCAACCGGGTCAGATGCAACCGGGTCAGATGCAACCGGGTCAGATGCAACCGGGTCAGATGCAACCGGGTCAGATGCAACCGGGTCAGATGACAGGTGAGAGTTGCCGTGCAATCAGTGCTGATGCTGGATTGAACGTGCGATCGCAACCCGAGGTGGGTAGTGAAGTCATCACCACCTTGCCTGATACCACCCAGGTGCAAATTCAAAATCGGGGTGAAGATGGATGGGTGCCGATTTCAGAACCGACTCCTGGGTATGTTGCCGCCGAAAATCTCATGATGTGTGGTCAGTAGAGTATCAAGGTTAAGAGTCCTGACTCTATCTAACTCCACTGCGGGAAAGGACGGGTATAACTCCCAAATGTTATCCCCTCCTTTCCCCACCAGAAGGGTCCGGCGATGCCGGACCCTTTTTGATGTCGATCCTCTCGCGATCGCCTCAAAGCAAAATGCCCCTTTCTGTTTCCAGAAGGGGGTAATTTGCCGTAATTGCAAAGGGCTTTCAACAAAGGGCCAAAAACCCGTTTCTTGCCCTGGAAAGCTCAAACAAGACCCGCATCCTAGTCCAGAAGGAGCAAACCGCCTACTATAGTTAAGAACCATTAAGCAAATCTGAACCTAAACCTTATGAAAATTGCGATCGCCGGTGCAACAGGATTCGTTGGCAGTCGATTAGTAGAGAAACTCCAACAAGCAGGTGATCAAGTCTTGATATTAACCCGCAATCCGACCAAAGCCAAGCGCGTCTTTCCCGATGCCGCCTTTCCCAACTTAGAAATCATTGCCTATACCCCCACCGAATCCGGTCCCTGGCAACAAGCACTCAGCGGATGTGATGGGGTGGTGAATCTCGCCGGTGCTCCCATCGCGGACGAACGCTGGACCCCGGAACGCAAACAGGAGATTCTCAACAGTCGCAAATTGGGAACCCGCAAAATTGTCGAGGCGATCGCCACTGCCAATCCCAAACCCTCCGTCCTCGTCAATGCTTCCGCCATTGGATATTACGGGACCAGCGAAACCGCCACCTTTGACGAAACCAGCGCCTCGGGTAACGATTTTCTCGCCCAAGTCTGTCAGGAGTGGGAAAACGAAGCACAGCAGGTCAAGCAATCCGGGACCCGCTTGGCAATTATTCGTAGCGGCATCGTCGTCGGCAACGGAGGGGCGATCGCCAAAATGCTCACCCCCTTTCGACTCCTCGCCGGAGGCCCCCTAGGCAGCGGCCATCAATGGTTTTCCTGGATTCATCGCGAAGACCTAGTAACCCTGATTCTCTTGGCCTTACACAGGTCCGATATCCAAGGCATCCTCAACGGCACCGCCCCCAACCCCGTCCGCATGAACGAATTATGTCACATTCTCGGACAAGTTCTCCATCGTCCCTCCTGGTTACCCGTCCCGGATTTTGCCCTCCAGCTAATCCTCGGTGAAGCGGCACAAGTCGTCCTAGAAGGACAACAAGTGTTACCCAAACGCCCCCTAGAATACGGCTTCGAGTACCGCTATCCCACAGTCAAACCCGCCCTAGAAGAAGTGGTATCTCACGGGTAACAGGAAGCACAAGAATAAAATCTAAAATTCTTCCCCAGTTCGTAGTAACGACTTCAGTCGTTATCCCCAGTTCGTAGTAACGACTTCATACCAAATCCGGGTATGAAAAGTCGTTTTTATGGAGTAGCCTGCGTAGGCAGGCTTTGTCTGTATAGCCCCAGGCTTGAGCCTGCGGGTTTTTACAGACCTTTGACAACCGGACTCCGTATCAGTCGTTATCCCCGGTTCGTAGTAACGGTCAGGACTTACGCAGATTTTGAGAATCTACCCTAAAATGTAGAGGCGATTCGCGTTCTCGCCTCTACATTGAGGGTTTAATGTTTAAAGAGTGCGTAAGTCCTGAAACTGTAAAAGGTAACGACCCATGATTGTGGCAAAAGGTAACACCCCACAGCTTACCCCCGAAGAATACTTTGCCTGGGAAGAACAGCAGCTAGAAAAACATGAATTGATTGACGGTCAAGTTTATGCCATGACTGGCGGTAGCGTTAATCATAGCCGCATTGCCATTCGATTGACGACGATGTTTGATACCCATTTAGACGTGAATCGTTGCATCATAGGGAACTCAGACTTGAGAGTTAATATTGTTGACACCCATAACTATATCTATCCAGATGCCAGCGTCACCTGTGACGATCGCGATCGAACCACCTCCCAATACATCACCTATCCCTGTCTCATTGTGGAAGTCCTCTCCAATACCACCGAAGCCTACGACAGAGGGGGCAAATTCCGAATGTATCGCCAAAACCCCGCCCTCATCGATTACCTATTAGTCAGTTCCACCCGCATCGAAATGGATTTATATCACAAAAACGACGCAGGCGATTGGTTGATTATCAATTACAAAGCAGGGGACAGAATCGAACTCAAAAGCATTAACTTAAGTTTTCCGATTGAACAAGTCTATCGCGGTCTTGATCTAACCCTAGAAACCCAAACTTGAGATCAAACGATGACCCTCAACGAACTAACCCCACGCATCCGGGAACAGATCACAGTCAGAACTGAGGTATTACCCCTATAGTAGGGTTGCCTAGGAAAATATTCGTAAGTCCTGCTAGAATAAAATTAGCCATTAGTTTCCATTTCGCCTAATCCGTGAGCTATAGCAATTCTTGCAGCAGTTGTGTAATAAGCCCTCACCCCCAACCCTTCGCCTTTAAAAGGGAGAGAAACTCGGGGTGAGGGTATGAATCATTTAGGATTGCTATAATATGATGGCATTTATTAGCAAATATGAAATCTAGCAAAGCAAAATATTCAAAAAATGCTTACTCTAAAACCTGTTGATGTGGGTACTAAAATCAAGGCAAAATCTATGGAAAAAGTCATTCACAAAACAACGAAAAAAGAACAAACTAGCGACTTTCAATACTGGCAAAACCAGCCCCCCCTTAAACGTCTCGAAGCCCTAGAACAAATCCGTCGAGAATACCATCAATATAAATACCATGCTGAACCCAGATTTCAAAGAGTTTATACAGTTGTTAAACGCCAATCAAGTTAACTATCTGATTATTGGGGGTTATGCCGTAGCCCTGTCAAGGTGGTAAATTTAATGACCCCAAATCCTTATTTCTTGGACAGGCGATCACTCTCGCGCCCCTACAAGAGGTAAATTTAATGACGAAAAATCAGGGTTTCTTGTAGGGGCGTATTGCATACGCCCTCTTTTGGGCGTATGCAATACGCCCCTACAATCTACACACCTTGACAGGGCTAGGGGTTATGCCGTTGCTATTCATGGACACCCTCGCTACACCAAAGATATAGATATTTGGATAGAAATGTCATCAGAAAATGCCGATAAAATCATAACTGCCCTTGAGCAATTCGGCTTTGGCAGCCTGGGCTTATCTGCCCAAGACTTTCAAACCCCTGACCAAATTATTCAACTGGGTTATCCTCCCAATCGCATTGATCTCATTACCACCCCTGACGGCATTGATTTTGAAACCTGCTATCGTTCAAAAACCGAGGTGATTGTTGATGATATTCCGGTTCAATTTATCGATCTGGACAATTTAAAAAGAAATAAAAAAGCATCGGGCAGACTGCAAGATCTAGCCGATCTAGAAAATCTGGAATAATGCCGTATTACGATGCTGTAGAAACCATTATTGAGGGAGTCAAGGATACCGCTAAAACGGCTATATCTGGCATACCATTGACTCAGCCAAAACCCTCACCTCTTTCTCCCCAACTCCCACCCCTTCATCTAGCCCGATCGCCCTTACTCCAGGGCAAACATTCCTATAACCCCCAACAAAGAGTTATTTTTCCCCAAAAAAATGTGGCTGTACCTGAATTCAGGACAGCCGCCCAAGCTTATTCTGTGTAGAATGTGAAGTTTTTTTAACTTCCAACTAATCTAGGGCGTCCCCTAATTCGGGGTCCGCTTCCAAATTATCCGGATCAACATAGTGACAGGAATTTTCGACGCAAATCAGCGCCCAACCAGAATCTTCAATCCCCATCAACTTATAAGAGGCTTCTTGAACGAAAAATCCTTTATGATTACGGGTCTCGGGTTTGACAGTAACGTTATCCATAGTCATTTCTACTCAACTCCTTGTTTAAAATGCAGATTTGCGATTACCCTCTTGCTAAAGGTTTATCGCTAAGTTCATCAAATCTTATCATTAAAATAACCTTTTTTTTATTAAGTTTTTCAAAAAAATATGAACAAATATAAATACTTACGGTATTCAGGGTTGGTATGACTTGAGGTACTGTACCCCAACCCCAGGATATAGAACAAAAATGCGAGACAGAAGTAACATTTCCGTTCCAGTCTGGGCCAGTCGCCGGGGCTTCTGGGAAATCTTAAAACATTGTTAAAACTTGAATGAGAATGCTCCAGGGGCTGGACCCATCAAGGGTTGTCACCCGTTCTTGGGTTCACGGCCTTCCCAGGAGTGGTCCTCAATTTGTCCGGAGAAAATTGCCCTGGGAATGAGTCGGAAGGCGGTGGAGTCGGGAACGCTCCAGAGTGGGAACTATTGGAGTCATATCCGTGATCACGGACTTGAGTCACAAGACTATCATTTCATGTTAAACCTTAAATTAAGATCGTGCAGGAGAGGGGATGCCGTAACCGATGAAGAGGCCATTATTAACAGCAGTAATCCGAAGGAATAAGGTCGGGGCGATCGCACCGTTGCAAACCCTGACCACTCAAGTATTAATACCTGTAATCCGAGGGAGTCAAGTTGGGGCGATCGCCCTCTTGCAGACCCTGACTGCGACCCTAACCCTCGCACAACCTCAACCCCCGGTAGAAACCACGAGCTTTTTCTGTGGGACCGTTGAAGGAATTCCCGCCACAATGGCGCGTACCCCTAACGGGGAAATGCCGATGGTGATTTGGGATAGAAATACCCTCAAAGATCCTAATAGTAACCCTCAACAGCAGTGTGAGGAAGTCTCCACGCGCTTTCAAACCTACTATGACAACGGAACCCTTAACTATATCACCAGTGGGATTATGAACGGCCAACTGGTCGCCTGTGTTGCAGAAGGAGAAAATGAACCCTGTAGCGGGATGTTGTTTCCCCTCAGCGGTGGCAGCAATCCCCGAGGAATGTTGCAACGGATGTTCCGAATTCGGGTGGCATCCGCCGGACCGATCGCCGAAACGACCGATCGCCTGTACATCAGCTTTGATAAGTATTTAAACGGGGAATATCCCCAACTTCCAAGGGGAAGTCGGACTCCCCCAGTGCCTCGTCGAGACGTTCCCCAATCAAGGTAAAACACAATGAAATGGTCTAGGACGGGACTATCAGCGGCAATCCTGGGGGTAGGGGCGGTAATTTTAGTAGCAAAAGCTCCCATTTCCCTCCCTCAAACCCAGGGAATCGAAGAACAGGCGATCTCGGCAATGGGTCGCGAGGTTTCGGTGGTGATTAATGGCCAAAATCCTGGTTCTGGGGTGATTATTGCCCGCAATGGCAATACTTACACCGTTCTGACGGCCAAACACGCGATCGCCACCCCGGATGAGTATGCCATTCTCACCCCCGATGCTCAAACCCATCCGGTGGATTATGGCACCGTCAAAAAACTGCCCGGAGTGGATTTAGCGGTGGTGGAATTCACCAGTCCCAACCCCTACCGCGTCGCTCATTTCGGCAATTCTGATGACGCAATGGAAGGGGCGACAATTTATGTATCCGGTTGGCCCCATCCGGGACGAGTGATTACAGAACGGATTTATCAGGTTGCCAAAGGGACAATTTCCGGTCGCCCTCTCACCGCATTAGAGGATGGGTATGGGTTGATTTATACTAATATCACCCGTTCGGGGATGAGTGGCGGTCCGGTATTTGACAATCAGGGCCGGTTAATTGGCATTCACGGACGGGCCGAAGGGGAAGCGATTTACAATCCCGATACTGGAGATACGGTGGATGTCAAATCCGGGTTTAATGTGGGGATGCCCATTAATACCTTTGTGAGTCTGGCGGCGGAAGCGGGGATAAATGTACCTCGCTTAGGGGATAATTTTACTGCTGCGAGTCTGACTCTACCGGCACATTCGGCGTTAGTGTTAGCAGTGGCGGTGGCCCCGGACAATCAGACGATCGCCAGTGGGAGTCGAGATGGCATCATCAAACTTACCAATGGGAATAGCGGCCAAGAAATCCGCACCCTCACCGGCCATACTGATGCAGTAACGGCTCTCACGTTTAGTCCCGATGGACAAACTTTAGTGAGTGGGAGTGAGGATGGGACGGTCAAAATCTGGAACCGGCAGTCTGGGGAACTGGTGAGAAGTTTCCAAGGCGATCGCTCATTTGTGCGGGCCTTGGCCTTTAGTCCCGATGGCACTCTCTTGGCGTCCGGCAGTGCGGAAGATACAGACATTAAACTCTGGAATCCCCAAACCGGAGACTTAATTCGCACCCTCACCGGACATCGGGACTATGTGAATACCGTGGCCTTTACTAACGATGGCCAACTCCTAGTGAGTGGCAGTACGGATAAAACCATCAAACTCTGGAATCCCGAATCGGGAGAAGCAGTGCAGACCCTCACCGGGAATGCCAACCGGATCACCTCCGTTGTCACTACGCCTTATGGCAACCTCCTCGCTGCCGCCAGTGCAGAAGATGGACTGGTCAAAGTCTGGAATCTTCGCACCGGGGAATTGCTGCATACGTTAACGGGTCACAGAGGAACGGTTTATAGTATTGCCATTGACCCCTACGGCCATATTCTCGCCAGTGGCGGAATTGATGGGACGATCCAGATTTGGAACCTTTATACGGGGAATCGGGTGCGAAATTTGGAAGTGATCAATTCAGGGAGTGGCCATCAAAGTCCGGTGTTTTCCCTCGCCTTTTCTAGGGATGGTCAAACCCTGGTCAGTGGTGCCGATAATGGCAAGGTTCAATTGTGGCAAATTCCCCAACGTTAACTGTATTTTAGAATTCTTTTAATCTCATGGTTCGGAATTGGTATTCTGGCATTTCCACGGTTTTATTGAGCGCTACAATTGTAGCATTTTCCTGGTCATTTGCTTATCCCCAAACTGTCGATGAGCGAGTGATTGCAGCCGTTGCAAAATCCATGACCGTAATTATTAATGGTCAAAATCCCGGTTCGGGAATTATTATTGCCAAACAGGGGAACACTTACACTGTTTTAACGGCGAAGCACGTTCTGGCAACCGAAGATGCTTATCAAATTGTCACCCCCGAAGGTACGGTATATCCGCTCAACTATAACCAGGTCACTAAACTGCCGAATTTAGACCTTGCCTTGGCCCAATTTACCAGTTCTGAAAATTATCCCGTGGCGGTGATGGGGAACTCGGATACGACGACAGAAGGAACCGGGGTTTATATTTCTGGATGGCCGCATCCGGGAGAGGCAATTACCCAGCGGATCTTTCAATTTACCTCGGGAAAACTCTCCGGGCGAGCGATGGGGGCGGCAGATGAGGGATATGAATTAGTTTACACCAATGTGACGAGATCGGGCATGAGTGGCGGCCCGGTTTTTGATGAAACTGGGGTGCTGATTGGCATTCACGGACGGGCCGAAGGGGAACCCATTTATAATCCTGAAACCGGGGATACAGTGGCGGTCAAATCCGGGTTTAATTTAGGGATTCCCCTGAATCTCTTTTTAGAAATTGCTGTCGAAGTTGGGGTTAATTTACCCTATGCTCGATTTAATTTCTTTTCCGTGCAGGATTTGAAAGTGGATGACAAGTTTTTCGTAACTTCGGCAGCGATCGCGCCAGATAATCGGACGGTGATTGCGGGTTATGGAGATGGAATCATTCGTTTGTGGGATTTGTCTACCGGGGAGTTAAAACAAACCTGGGATCAAGGCAGTCGCCATCACACCAAAAAAGTCCATATTACCCCCGATGGAAAATTTTTAGTTAGTCTACATCGTCGGGATGCAGAACCGGATATCATTCAGGTTTGGGACTTAGGAACGGGTGCAATTCAACAGACTTTTAATGGCAATTTTTTCACCGCGATGAGTCCCGACGGTCAACTGATTGCCACGGGAAATCATGGTGAAAATGTGATTAATTTGTGGGAGGTGGAAACCGGAGATTTCAAGAGGGCGATCGCCCTAGAAAATGAAGTCACCGATATAGCCTTTAGTGCCGATGGTCAATGGATTGCTGTTGCGAATGCTTATCACGGGAGGATTTTGAATTTAGCGACCCAAGAACCTGTTCAAACAGCGCAATATCCCCTCGATACTCCCGCGAAACAAACCGTGCGATGTGTTGCCCTTAGTCCCGATGGAAAAACCTTTGTCACGGCCTTAATGCCCAGAGCAACGAGTGCCTATAGTAGTACAGCAGGTCGAGTGATTGTTTGGGATATTCAAACCGGGGAAATCCTCAAAAATTGGGCGATTCCTAAAACCCATATTAAATTTAATTGTTCTTTGTTTTTTGACCCTTCTGGACAAAGATTAGTGTTGGCAGGAGGGTCGGTTGAGGATGAAGAATCGGTGTTGATGTGGAATGTACAAACCGGCAATCGACTGTTTTTCCCCGAAGGGAAAACCGTGGCGGCCTTCAGTCCTGATGGTCAAACTTTTGTGACAGGCCGTTACGATCCAAATAGTATGGGGGCCGGTGCAGAATTTATGACGATTTGGCGACCTAAACCTTAGAAAAAATGGTGAAATATGAGTCAAGATTTTGTTAATTTTAACCCAACGGTGGTGACGATCGCCATTGCTGGGATGATGGGGGTTTCGATGCCAGTGGCGATCGCTCAACTGAACCAGCAGCAGGTGTCGGCAATGGCAGAACAGGTAACCGTCTTGATTCAGGGACAAAATCCCGGGTCTGGGGTGATTATCGGCCAATCCGGGGAGTCCTACTTTGTTCTCACGGCCAAGCACGTTGTCGCTACACAGGATGAATATTACATTGTTACCCCGGATCAACAACAGTACCCCCTCGACTATCAACGAATCCATAAGATACCGGAAGCTGATTTAGCAGTGGTTCAGTTTACCAGCGATCGCAGCTATGACCTGGCAACCATAGGAAATTCGGATCAAGTTATCCAAGGGAATATCATATATGTTGCGGGATGGCCTCATCCAGGGGAAGCAATCACGGAACGGATTTTTCAACTCACAACCGGGACGGTTTCAGGGCGATCGCTCTCAGGAACTTCCGACGGGTATGAATTAGTTTATACGAATATTACCCGTTCGGGGATGAGTGGCGGTCCTCTATTTGACCAAAACGGTGAATTAATTGGCATTCACGGACAATCGGAGGGACAAAATATTTATAATCCTGATACGGGGGATATGGTGTCTGTTAAGGCGGGATTTAATTTAGGAATTCCCTTAGCGACTTTTATGCAATTGAGTGCACCGAACCCCTTGCCACCGAACCCCAGCTTTGCCAACCCCCTGACCCATGCGGCAATCCAGGCATTAGGAGAAAACCGCGTGGCCGATGCCATCGGTTTATACAAGCGGGCGACGGAGGTGAATCCGGAGTATTTAGAGGCAGTATTTGGACTCGGACAGGCGTATTATGAATCCGGCGATCGCAACATGGCGTTGAGTCAGTTTGAAAAGGCAGTAGAATTAACTCGCGCTGAAATGGAACGACTCCGATCGCTGGGTACAGTGGAAGTTCTAGCCTATAATAATCAGGTGAATGTAGAATTGGCCTTGGGAACCCTGTTGTTTACATCCGGCGATCGCCTTGAGGGATTAAATCTGCTCGTCGGTCTTTTGCAATATAATAACCAAATGGTGAGAGAAAAACTCTTTCAACCGGATTTTGCCAGTAGTCGCCTGCGGAGTGATGCAGTCCCCCTGCAACACTATGGTGAAAAAATCCTATCCACCGAAGCGGGTAAATTACCGCCTGAATTCAATCAGGGACAGGTTCTCTACGAATTGGGACAAGTTCAGGCAGCGATTCCCTACTTTCAAATCATCCTGGATAAATATAAAAATGACCCCCGAGTGATGTTAGCACTCGCAGTCGCCTTACAGGAAACCGGCCAAAGCGATCGGGCCGATGTCTTACTCCAGGAGATCCAAACGGAACAATCCCAGGAAACAGTGTCCTGGGAATCTGGAGGATGGTTGGGCATTTTTTGGAGCGATCGCCTGATTGAAAAAGCTCGACCATTGATTCCTCCTCAGACGTGA

Protein sequences of DBSCAN-SWA_2

>NC_019693|1667210:1742727|1667210_1668551_-|WP_015147718.1|protease|DBSCAN-SWA
MSKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVDLCNEILDEELFDSNAAAPQPVPRTEQPQKRRTRAANISLNQMPKPREIKKHLDEHVIGQDEAKKVLSVAVYNHYKRLSYTQAKASGKIGAEDPVELQKSNILLIGPTGCGKTLLAQTLADVLEVPFAVADATTLTEAGYVGEDVENILLRLLQVADLDVEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGTVANVPPQGGRKHPYQDCIQIDTSNILFICGGAFVGLEKVVEQRTGKKSMGFIQPGDAQSKEKRTADILKNLQPDDLVKFGMIPEFIGRIPVLAVVDPLDEDALTEILTEPKNALVKQYQKLLRMDNVNLEFKPDAIRAIAQEAYRRKTGARALRGIVEELMLDVMYELPSRKDVTRCTITREMVEKRSTAELIVHPSSLPKPESA
>NC_019693|1667210:1742727|1722589_1725271_+|WP_015147753.1|DBSCAN-SWA
MLHILLLEDSLLDAELIEAHLLESGLNVALKRVDTCDAFQNALESGSFDVILADYSLPSFDGFSALKMAQLRCPDLPFIFVSATLGEEVALETLKNGATDYVLKQRLERLVPSVQRAIREATEHRDRLKAEAALQESDRRFRMALKNSFICIFQQDRDLKYQWIHNPQGPETAEEIVGETDYFLFSEADADYLSTLKREVIATGSPNRFEISVTISGEIRDYDLILEPVFEDEENQDNPQVVALMGTALNITERKRSERELYRREQQFRALAENAPDIIARFDQQLRHIYINPAIEKATGIPPQEFIGKTNAELGFPEDIYLQWSRHLQNIFVTGEPSFLEFEFPSSTGTRTYQSQAVPEFDLEGNVESLLCISRDMTESKQAEQVLRESEARFRRLMDSNTIGMGFWHGEAITVANDAFLEMMGYSQEDLQREPLNWREITPSEYLHLDANANQQARQTGYTEPFEKEFFHKDGTRIPVLLGGAIFDNNADAGVFFTLDLTERKRMEKALQQQAEALERANQVKDQFLAVLSHELRSPLNAILGWSQLLLARKFDEATTRRALETIERNARFQTQLIEDLLDVSRILRGKLTLKVTRVNLSTPICAAIESLRLAIEAKSLQLDYSPNPSVSPVMGDSNRLQQVVWNLLSNAVKFTEPGGQVSLNLKQQDHWVILQVQDTGVGILPEFLPHLFEYFRQADASSTRNHGGLGIGLGLVRHLVELHGGTVSAESPGEGQGATFIVKLPAIAFKADPNIQLPQVSPKQKLTGVRVLVVDDDQDSLQFMQFVLEQSGCQVRAIASPIEALAVFSDWQPDLLISDIAMPEEDGYSFIRKIRAMERNAGGQIPAVALTAYAREEDRNAAFLAGFQEHLTKPIDPKVLMAAIELLTRPIE
>NC_019693|1667210:1742727|1728929_1730015_-|WP_015147756.1|DBSCAN-SWA
MTTTLSTPSAIASILGDEAEDLLTYQAQLPKQLFQLPGPDWIDRVASHSDRSVPVLRSLQQLYSHGNLANTGYLSILPVDQGIEHSAAASFAPNPIYFDPENIIKLAVAGGCNAVATTLGVLGSVSRKYAHKIPFILKLNHNELLTVPNQYDQIMFASVEQAWNLGAVAVGATIYFGSPESTRQIQEVSAAFAQAHEYGMATILWCYLRNSAFKQDQDYHLAADLTGQANHLGVTIQADIIKQKQPECNGGYGAVSQALGQKYGRTDKRVETELSSNHPIDMTRYQLLNCYAGRAGLINSGGSSAGENDFAQAVRTAVINKRAGGCGLISGRKAFQRPFEEGVKLFHTIQEVYLSSDVTIA
>NC_019693|1667210:1742727|1685991_1686468_-|WP_015147730.1|DBSCAN-SWA
MTELIEAIKTGEKSQVEALLQGNADVNQKDADGLTALTAAAESGNLELVQLLLDAGAEAKNADNDGWTALMSASGSGKVEVVEALIAAGADINAQSEFGVTALITAAGNGHEAVVQCLIDCGADIRMKDRNNWTALVWAAEEGHPKIVDVIKQARDRT
>NC_019693|1667210:1742727|1686536_1688333_-|WP_015147731.1|DBSCAN-SWA
MQKRISQGAESAGAALAIVPAVFVTILIINYSINVPFADQWFNAGLTIEQFSENTLSLGDLIAQHNESRKFFPRLIFLSLAYLTRWDVRVEMLVSLFLAAVVSANLYRLNRITVNRPLAQSLFIAFLANLLIFSPIQYENWLWGIQVVVFLPIACLTTCIGVAHSKLSQFTKFTICTALCTISTFSFANGMLLWIVVLPVLAFARSHREIIRKKWWIVAWVAFFAANLGLYFYQYEKPNHHPRFSYAIQHPGETFHFFLGFLGAPLAQVNPSHSLIVATGVGLAILLISIAACGYLVICQDGELLDRAKGWLAIAAYSGMSGALTSLGRVGFGIDGALASRYTTFSVYLLIALVHLIPILLAHVNRNGVFLPRKLFTTGFAASLATALIGLHLFTSLAAIEQMSVMRRDRLQAKACLLLSQAIDTQKCLFERVFPVPLDSFSPEKQERVKAKFARIVTRLDQLGFLDLGLVKSKDISQIAGTLPVGADSGWFDSLEQVDERVYRASGWAILPERNQAADAVILTYQDDNQRAIGFAIADVRVQRNDVNQQRQLREQLWLGWQTHFSANTLPPGPLKIQAWAFDALTGKAYPLNGIRQL
>NC_019693|1667210:1742727|1709871_1710045_+|WP_156823762.1|DBSCAN-SWA
MTILGNDGIRWSLLIGFNRSDEAIATLSRESRPFRARLNFPTRPEKRYNIAVDTQER
>NC_019693|1667210:1742727|1708114_1708897_-|WP_015147744.1|DBSCAN-SWA
MRILLVEDDEPIAQALVATLKQQNHVVDVATDGLLGLELAQACDYDLLLLDVMLPKLDGISLCRKLRSCGYQMPILLLTAKDSTEDKVKGLDAGADDYLVKPFDLPELTARIRALLRRGTAPLPPVLEWGALQLNPSTCDVTYHNQPVTLTPTEYRLLELFMRNSSRVYSRSAILDHLWSFDEPPSEDTIRAHIKGLRQKLKSSGAPADAIETVYGLGYRLKPIQEEKLVQPPRILMAGLPDELGFWLQQRLGRRFSKRA
>NC_019693|1667210:1742727|1734418_1735003_+|WP_015147761.1|DBSCAN-SWA
MIVAKGNTPQLTPEEYFAWEEQQLEKHELIDGQVYAMTGGSVNHSRIAIRLTTMFDTHLDVNRCIIGNSDLRVNIVDTHNYIYPDASVTCDDRDRTTSQYITYPCLIVEVLSNTTEAYDRGGKFRMYRQNPALIDYLLVSSTRIEMDLYHKNDAGDWLIINYKAGDRIELKSINLSFPIEQVYRGLDLTLETQT
>NC_019693|1667210:1742727|1710083_1710566_+|WP_015147745.1|DBSCAN-SWA
MILNVNVITPSKTIWNAPSSEVILPTSTGQIGILSGHVALVTFIKVGVMRIRYQNTWIPIFVKGGFAEIEGDIVTVLVNDAERGDRIDPEIAHSELEKAQAQLSQASNSLEKIRAQLFLKQARARDTAAREFPDSLQLDIPDPIAAKNAAVSALKVIEQL
>NC_019693|1667210:1742727|1739508_1741212_+|WP_015147768.1|protease|DBSCAN-SWA
MVRNWYSGISTVLLSATIVAFSWSFAYPQTVDERVIAAVAKSMTVIINGQNPGSGIIIAKQGNTYTVLTAKHVLATEDAYQIVTPEGTVYPLNYNQVTKLPNLDLALAQFTSSENYPVAVMGNSDTTTEGTGVYISGWPHPGEAITQRIFQFTSGKLSGRAMGAADEGYELVYTNVTRSGMSGGPVFDETGVLIGIHGRAEGEPIYNPETGDTVAVKSGFNLGIPLNLFLEIAVEVGVNLPYARFNFFSVQDLKVDDKFFVTSAAIAPDNRTVIAGYGDGIIRLWDLSTGELKQTWDQGSRHHTKKVHITPDGKFLVSLHRRDAEPDIIQVWDLGTGAIQQTFNGNFFTAMSPDGQLIATGNHGENVINLWEVETGDFKRAIALENEVTDIAFSADGQWIAVANAYHGRILNLATQEPVQTAQYPLDTPAKQTVRCVALSPDGKTFVTALMPRATSAYSSTAGRVIVWDIQTGEILKNWAIPKTHIKFNCSLFFDPSGQRLVLAGGSVEDEESVLMWNVQTGNRLFFPEGKTVAAFSPDGQTFVTGRYDPNSMGAGAEFMTIWRPKP
>NC_019693|1667210:1742727|1714758_1715859_-|WP_015147749.1|DBSCAN-SWA
MVPVALRMIWEAKGRFAIAVLGIAFSVMLMLFLLGVYQGVKFGSKSYVLHTQASVWVSQRNTRNLIKTSSFLPETLGNTLSQVEGVKSVDSLLRAIAPAEFPDKTVTLYIFGFDSNSQIGAPEISSGTSTLQPQEIILDRAFTATHNLKLGDSLSLQGYPFKIVGISQGTNLIVGQFAFTRLDDVPRLLGLQNVRSFFLLNLDSDSPEIISRLEAQFPDLVFIPQAEFAANNVEEMEIGVLPILWTIVLFGAITGGTVIVLMMYTSVLEKREDYAMLKAVGASQKFLGILVLKQSMLAALLGFSVGFIIDITFAPLLTEVIPSLLLVFTWQDATGVLIACLILGAIGTLAPIRTLKNIYPAEVFRA
>NC_019693|1667210:1742727|1701972_1702851_+|WP_015147741.1|DBSCAN-SWA
MALVKIHDFYPNYRDEIFGGTDIKGMDIYAGTTDEKVGTVYDILLDDTGRFRYLVVDTGFWIFGKKVLLPIGSARIDYDAGRIYAIGLVDKNQAEQLPEYDELQPIDYEYEERVRDVYRDRTAVTDTAAATPAASTTATRNRDTYHYDQEPHLYDRNDTDHRNLKLYEERLIANKDRYKAGEVAVGKQVETEVARAAVPVEKERVVIERTSAGMSDAQAVAPGTANFQEGEVARAEVYEETADIHKEAFVRENVEIHKEVERDMVEGQETLRREELKVDTDGKPVVERRPRK
>NC_019693|1667210:1742727|1699415_1700066_+|WP_015147739.1|tRNA|DBSCAN-SWA
MVRVRVRQHVNPLSYAYQTPIVPPTWSQIYTNSAQPLHLDIGCAWGRFLLQMAPIEPEWNFLGVEIREPLVEGALAERDEQQFSNLHFIFCNINHAFAPLLDSLPPGVLHRVSIQFPDPWFKKRHQKRRVVQPELVEKVAKYLVPGGMVFLQSDVHEVAVEMRDRFAEHPSFARQGSEEWLPENPLPVATEREQSTLEKNEPVYRVVFLKTREIPG
>NC_019693|1667210:1742727|1718438_1721876_+|WP_015147751.1|DBSCAN-SWA
MVRPIPRSPVFSYSAAVFTVVIALLLTVTFKPILASTLFLFFFLAVTGMTWYGGIGPGLVTTILSVLALDYFFLVPTHSLTVLSGTNLLRMGLFVLVTLAIAKLNTKLQQTKRQLEISLSQLKQSEERYRRIVETASEGIWILDEAGRTRYVNQRMAQMLGCSPESMLDRPFFEWFDQGSRPEGYQTLTQPYPGYPEQWDGRFRRSDQSLLWAIVSMNSIFDDQGQFQGTHLMLTDVSDRQQTQERLQLSLEAGRMGFWDWNLSTNEIVRSDNLAEIYGVSPGQLEQTFESSLNLIHPEDRERVQEAIAQAVAENTPYSLEFRIQPSPENIRWILGKGRVFKDAQGTAVRMIGIAMDISDRKQTEEVLGQTQQRFETFMNYSPVAAYFKDEAGRYIYVNPIVERLWQRSQEKWVGQTDADLFPEAVAQELQAHDATVLETDQALEFLETVEHLDGKHYWISWKFPMHEPSGRRLLAGISLDITDRKRTQEERDLLLANLESQQELLSAVLQQMPAGAIVAEAPSGQLVLMNQQVREILGISLTPLITIPSYLHTSYQIFHPDGQPYHPDALPLARSISQGEVVVEEELQIQRADGTRVTVLANSGPIRNAEGEIVAAVVTFYDITAQKRAQAEIKRYADVVKNIQVGLSVWQLTPGEEPPSFELISANPAASQLAGRDLDRAVGMRIETLFPHLVKTSRIAELIEVLNSSSAREFPEVIYNDDAGEERCCSMKAFSLPNRCLGLAYEDITDRKQAQFALLESEQRFRTMADAAPVYIWLSGIDQLCYYFNKPWLEFTGRTLEEEIGNGWTEGVHPDDFKFCLDTYQKSFDLRQPFEMEYRLRRYDGEYRWVLDRAVPRFSPDGRFEGYVGSCIDISDRKLYEGEIKRLNASLERRVTDRTAQLEAANQELESFAYSVSHDLRAPLRHISGFVNLLRKRIEPSLDENSQRYLDIIVASTHQAEELIDNLLAFSRMARAQMRFIKVDMNQLVNEVRQTLEIHRGDRKILWKIASLPPVKGEPTMLRLVFQNLLDNAIKYSQRRETAEITVGFNESDLEFIFFVRDNGIGFDMRYAHKLFGVFQRLHSNPDYVGTGIGLANVRRIIHRHGGRTWAEGEVDLGATFYFSLPKQPEGDQVDASPNVLGST
>NC_019693|1667210:1742727|1679723_1683707_-|WP_015147728.1|DBSCAN-SWA
MFTHVKPTIRHIAPDDIRGRSLLKVVYVVLEAQYQSALSSAVRSINENNQNLAIEISGYLIEELRDSNNYEAFKQDLATANVFIASLIFIEDLAQKVTAAVEPHRDRLDVAVVFPSMPEVMRLNKMGSFSMAQLGQSKSAIGQFMKKRKEKSGSSFQDGMLKLLQTLPKVLKYLPMDKAQDARNFMLSFQYWLGGSSENLENFLLMLADKYVFKGQQTVKFQDPVVYLDMGVWHPLAPKMFEDVKDYLNWYNSRDDISDDLKDPLAPCIGLVLQRTHLVTGDDAHYVAMVQEIEALGARPIPVFAGGLDFSKPVDAYFWDVGAKGVEPLPLVDTVISLTGFALVGGPARQDHPKAIDSLKRLNRPYMVALPLVFQTTEEWQDSDLGLHPIQVALQIAIPELDGAIEPIILSGRDGATGKAIALQDRIETVTQRAIKWATLRRKPKLDKKLAITIFSFPPDKGNVGTAAYLDVFGSIYEVMNALKCNGYDLPELPESAEALMLEVIHDAQAQYNSPELNVAYRMSVEEYEKLTPYSERLQENWGPPPGHLNTDGQNLLVYGKSFGNVFIGIQPTFGYEGDPMRLLFSRSASPHHGFAAYYTYLEQIWGADAVLHFGTHGSLEFMPGKQMGMSGECYPDSLIGKIPNIYYYAANNPSEATIAKRRSYAETISYLTPPAENAGLYKGLQELNELIGSYQTLKESGRGVAIVNTIMDKCRLVNLDQDINLPEKDAIELTPEERDNVVGQVYRKLMEIESRLLPCGLHVIGKPPSAEEAIATLVNIASLDRDEEGVKSLLRIIANSIGRDIDELYANNDKGILEDVELLQAIIQATRAAVAALVQEQTDAEGRVSRVSKLNFFNMGKKAPWVESLHQSGYPNVSNDDLKPLFEYLEFCLQQVCADNELGALLRALEGEYVLPGPGGDPIRNPDVLPTGKNIHALDPQSIPTAAAVTSAKIVVDRLLDRQRRENNGEWPETIACVLWGTDNIKTYGESLAQIMWMVGVKPVPDALGRVNKLELLSLEELGRPRIDVVINCSGVFRDLFINQMNLLDKAVKMAAEADEPLEMNFIRKHAMKQAEEMGINLRQAATRVFSNASGSYASNVNLAVENSTWESENELQEMYLTRKSFAFSSDNPGTMEQDRQIFESSLKTADVTFQNLDSSEISLTDVSHYFDSDPTKVIGTLRGDGKKPAAYIADTTTANAQVRTLSETVRLDTRTKMLNPKWYEGMLSHGYEGVRELSKRLVNTMGWSATAGAVDNWVYEEANETFMKDEEMQKRLLNLNPNSFRKMVTTLLEANGRGYWETSEENLDRLRELYQEVEDRIEGIE
>NC_019693|1667210:1742727|1691735_1692698_+|WP_015147734.1|transposase|DBSCAN-SWA
MNTPNANYDQTWKEALEDYLEPFMAFFFPEVHNLIDWSRGYESLDKELQQITPTATSGEREADKLFKVWQKNGEEAYILIHIEVQSQEESVFPERMYIYHYRSFDIHKKVISLAILGDDRPSWRPNSYSYELGGSSVSFKFPIAKLLDYESQWETLKTSLNPLAFLVMAHLKTQASTGKAEEREQYKWELVQNLSERGYSEKDIIKLFRLLDWMMTLPESLQQSFDTKLKNYQEEQKMPILSNMERRALETGFQKGIQTARREMILEVLNARFNPVPAEVIDRINQISDYETLQQLLTRGISIGSLAEFEEVLASIMTDN
>NC_019693|1667210:1742727|1679339_1679636_-|WP_015147727.1|DBSCAN-SWA
MIDVRKAILAARDYFNSVQDLMSQNGPLDIQDLRLEEVELSEDKKYWFVTIGYDLPKSAMRNPLLPEVVRTQEWERNYKIFKINADTGNVESMKIREV
>NC_019693|1667210:1742727|1690011_1690149_-|WP_156823761.1|DBSCAN-SWA
MRKSSPIRLYGLLQIAIAIVARVHRRSCLGSAVAIATQRAVLFLG
>NC_019693|1667210:1742727|1737160_1737814_+|WP_015147766.1|DBSCAN-SWA
MKRPLLTAVIRRNKVGAIAPLQTLTTQVLIPVIRGSQVGAIALLQTLTATLTLAQPQPPVETTSFFCGTVEGIPATMARTPNGEMPMVIWDRNTLKDPNSNPQQQCEEVSTRFQTYYDNGTLNYITSGIMNGQLVACVAEGENEPCSGMLFPLSGGSNPRGMLQRMFRIRVASAGPIAETTDRLYISFDKYLNGEYPQLPRGSRTPPVPRRDVPQSR
>NC_019693|1667210:1742727|1736149_1736401_+|WP_015147764.1|DBSCAN-SWA
MPYYDAVETIIEGVKDTAKTAISGIPLTQPKPSPLSPQLPPLHLARSPLLQGKHSYNPQQRVIFPQKNVAVPEFRTAAQAYSV
>NC_019693|1667210:1742727|1684313_1685912_+|WP_015147729.1|DBSCAN-SWA
MSFAVYNESFYLTNNPDIQQAVNTGIFTSGLSHFQIFGLGEGRVQVSPFYDEATYLLNNPDVAAAVSNRSLTSGLQHFIALGEAEGRVNISPLWNENTYLSLNPDVAGAVNSGLLVSGLQHFLALGQAEGRPGAPPVSLTPAGFNESAYLAINTDVRTAVESGVLSSGLAHYQSFGQFEPNRAGVFLGTSGSDTINAFGQATGILGVGLSNITPLGIGGLDGIPTSLGVGEIDTLIGGPGVDIFNLGIGITPLKPNPQKLYVGLGNLDYGLIKNFQLEQDLILLAGEPREYRFDAADGNFLISTAGGDLVGIVEGVPNLQIRNVFDDGTFILSGGEGSVITEVPGFNDSVYLAVNRDVAAAVEAGVFPSGLAHYQAFGQNEGRVGVFTGSSGSDEITGFGPNTSLVGVAVSVVADSPNQDVVITSQGTGQVDVLVGGPGVDTFILGTGISFANSVIQPFYIGNGNEDYALIRNFEPGKDQIQLGGNPEEYTFQVADGNFNIFRNPGDLVGIVEGVTNIAVLQTFTTGRFLMS
>NC_019693|1667210:1742727|1727682_1728849_-|WP_015147755.1|DBSCAN-SWA
MKLAARVGQVTPSLTLAIAAKAKAMKADGIDVCSFSTGEPDFDTPNHIKMAAEKALNAGKTKYGPAAGEPLLREAIAQKLKTDNNLDYSAKNVIVTNGGKHSLFNLMLALIESGDEVIIPAPFWLSYPEMVTLAGGSPVIVSTTAESGYKITPDQLRSACTPKTKLFILNSPSNPTGMVYSPDEIRALAEVVVEQDILVVSDEIYEKILYNDIKHLSIGAVSEEVFKRTIISNGFAKAYSMTGWRIGYLAGDEELIQAASTIQSHSTSNVCTFAQYGAIAALESEQDCVQEMLQAFAMRRVAVLDRIRGMSGISCPEPEGAFYVFLNIAKTGMKSLKFCDALLESHQVAAIPGIAFGDDDCIRLSYATDLPTIEKGLDRLEKFLQQQF
>NC_019693|1667210:1742727|1710769_1711735_-|WP_044196617.1|DBSCAN-SWA
MKLHESSGRWRLGLGLSLVTVILWGVLPIALKITLQALDVYTVTWFRFSLSFGILVCILGMRQQLPSLEKLRGTSWKLLAVATGFLSVNYALYLQGLAQTSPANAQVFIQLAPVLMGLGAIAIFKERYTLRQWAGLGILTLGFVVFFHEQLQTVLAAPRTYLIGNIILVIAAAAWAIYALAQKQLLQQLTSSNIMLLLYGICALLFLPFSSPSNLLNLTPLEWGMLIFSGLNTVVAYGAFAESLAHWDASKVSAILATTPIVTLLSVWVISLGIPLPIAPEQLTVLAIIGAMLVVTGSVAIALGKRPHSPRKPGQFSQKSG
>NC_019693|1667210:1742727|1731294_1731840_+|WP_015147758.1|DBSCAN-SWA
MALALQTRAIGVFEDSQTTENALNALGEAGFLMDNILVATQDNIPDEMESPDSEFLENRTVEGLGKGVMNGTVFGAIAGLFSGLTTLFLPGLGPIAVVGPVATVAGLTAAGSFYGALGGAIVGTVAGDKFTEGQANIYHQHLTQGHYLVRLEGTEEQITQAESILREHGIQEWQIYQSTDN
>NC_019693|1667210:1742727|1722097_1722556_+|WP_015147752.1|DBSCAN-SWA
MDIKRILLVEDNANDIELILTGLAENNLANEVIVVRDGEEALDYLFRRGIFRLRREGHPILVMLDLKLPKIDGLEVLAQMKSKTDLRQIPVVILTASREESDLISSYNLGVNGYVIKPLDFHEFVDAIKSLGLFWAVVNQPPPGSLPAVARE
>NC_019693|1667210:1742727|1730325_1730946_+|WP_015147757.1|DBSCAN-SWA
MQVPVEITYRNLEKTEAIDNLVREKVAKLEQFCDHITSCRVAVEKNNERPSSGSPYRVRFDITVPPSHEIAAVCNPGEGNQYDELDTVIRNAYEAARRQVVELTQRQNNKVKDHPAQAMGAVVSQLFPEDGYGFIKTLDSGREIYFHRNSVLGDRFDELKEGAGVHFSETQGEMGPQATTVHLVNKLGPNEATEQQSNIEQPIGWK
>NC_019693|1667210:1742727|1706498_1708076_+|WP_015147653.1|transposase|DBSCAN-SWA
MRPPLWHPPVELSDSEQVIINRIKKAKLFTFLRLNRLFIFDDEFQEELNTIFKDSTMGNCPVAPAQLALATILQAYMGISDEEVIEELVMDLRWQLALNCLNCEKPPFSKATLIRFRSALIKKGFDQRLIDRTVDIAKLKGGFGSANLRAALDSSPLWGAGKVEDTYNLLGHALRKALSIIASQQGWGLAEIANEAGADFVNSSSLKAALDLNWDDPAESQKALSTILKSLNSVEEWIQQQSNPDEIEEAQAPLQVARLIESQNVTLDTMGVPKLAKGVAKDRRISIEDPDMRHGRKSRSQKINGYKRHILKDLDIGVIRAVAVTRANTPEAAATVDLEVDLKRQQVQLNELHIDRAYLSSHWVKERSEQLQIFCKAWPVRNSGRFDKNAFVFDWDNQVISCPNQVIMPFEPGKIVHFPKPECAACPLRERCTTSKNGRSISIHPDEGLMQELRQRQSTSSGRAQLRERTSVEHSLAHVGQWQDKRARYIGQRKNLFDLRRVAVVHNLHVIARMNEVLPIQQAAL
>NC_019693|1667210:1742727|1673716_1674607_+|WP_044196599.1|DBSCAN-SWA
MVNFGRVVTAMITPFNADGSVNYGVTEKLAVHLIEHGSDAVLVCGTTGESPTLTWEEEYELFQVVKKAVGNRGKVIAGTGSNSTREAIAATEKAANIGLDGSLQVVPYYNKPPQEGLYRHFKAIAQSCPDFPIMLYNIPGRTGQNLLPETVARLAEIPNITAIKEASGSLDQASLVRSLTPPEFQIYSGDDSLTLPLLSIGAAGVVSVASHLVGETLQSMIQAYETGKNQEATQLHLKLLPLFKALFTTTNPIPLKCALALQGWDVGSTRPPLCEASDEVKKALEVVMQQLNLLEL
>NC_019693|1667210:1742727|1678845_1679343_-|WP_015147726.1|DBSCAN-SWA
MNDYVSQVFKHYKSKGIVIDTNILLLWCVGTVNRSRISKFSRTEKFLPEDYDIILKVLEYFNKIVTTPNILTEVNSLVNQIGEPERSQCLQILGQGLTKLDEFYIESATVGRADNFKKFGLTDCGIIEVSRDKYLVLTDDFKLANYLQKIGIDTINFNNLRGLWE
>NC_019693|1667210:1742727|1676762_1677458_+|WP_015147724.1|DBSCAN-SWA
MNDSSSSIAQSILEFVRHSVPGYGIRGGFGVAALLMTLTLGYNSDSQTFAGDHPAVANRQAIANYQSPPLRDSGWGEVGVDTPFNRDRIQALFPNYRVESSQISREGMPQPVIEVYDDSILVARMDPQDANNPNLGILRITIYDESIAGPGGVTIGTSYNQTPGSSRFDCFPGEGPTTGYVICRSPESARIQYIYGPINRERVRPMMELPPENVLGNYRLDRLVWLNWQGR
>NC_019693|1667210:1742727|1677547_1678504_-|WP_015147725.1|DBSCAN-SWA
MLKAVIETVLREYPQANKEDFKNHPFASYMRNDIAPLLTRYLNLPEIYKIQSSAGNGAWATIPWIAVFNNLVTDSVRVGFFTAYLFCADFSGVYLSLLQGTDSKKKIYGLGVSREILRKQAKVFRGMISNDFQLELHEDIDLKLDTIPKETTARRLGQAYEAGHILSLYYSQVNLPSSEKMYADILSFIKIYEELVEHKISDNQELDSVSEEFWSEDLTKYRIHRQVERNQSLSKRAKEIHGYICKACKFDFEAHYGTIGHRYIEAHHIVPISSLSKTKVQLDPRKDFTVLCSNCHRMIHRIKPTPTLEEFKKLIKIK
>NC_019693|1667210:1742727|1672273_1673329_+|WP_015147721.1|DBSCAN-SWA
MEDCHLSKSYKVAILGATGAVGTELLELLDSRAFPMSELKLLASSRSAGKTLTFRGEEIPVEVVEESSFKNVDLVLASAGGSTSKAWASKAVAAGAVVVDNSSAFRMDPNVPLVVPEVNPEAAAHHQGIIANPNCTTILMAVAVWPLHQVQPVQRIVAATYQSASGAGARAMEEMKDQATAILQGQTPKTEIFPYPLAFNLFPHNSPLNDQGYCEEEMKMVNETRKIFGDPDIRISPTCVRVPVLRAHSEALNLEFAQPFSVSKAREILAAAPGVKLVEDWQANYFPMPMEATGRDEVLVGRIRQDISAPNGLELWLSGDQIRKGAALNAVQIAELLVTRNWIRPAAAVSV
>NC_019693|1667210:1742727|1690290_1691565_+|WP_015147733.1|DBSCAN-SWA
MEPVDIVILSNGPGELATWVRPVVRALQQQLGDRQAEVRISLILSPCPHATGKEGAIARSYPEIDRVQEAQHFWPFLLRGKTADNWDWREKGVVLFLGGDQFFTLILGKRLGYRTVIYAEREARWQQWIDRFAVMNSQVQPQDSQKYGHKFTIVGDLIADVAGNGGNEEEETGEWGEAGELIGLLPGSKPAKLMQGVPLCLAIAECIHQVRPQTQFVIPVAPTLEIETLAEFANPQQNAVLELVNGIAGELKRNENNDRAYLETASGLRVQLWRRSPAYDLLSQCTLCLTTVGANTAELGSLGIPMIVLIPTQQLDAMRAWDGLPGILANLPLFGTIFAKLINRLVLRQGKLFAWPNIWANSEIVPELVGKLQPQQVAEIAIDWLENPQKLQLIRDKLQSVRGQPGAAHHIAQIIIEEINNQFN
>NC_019693|1667210:1742727|1700157_1701573_+|WP_015147740.1|DBSCAN-SWA
MNPDDRPNPIPPQGNPGFRVAVARFFKFQEHQTNFRTEIIAGVTTFMTMAYILAVNPGILSNAIFLENSGDLFGELVIATALSSAIATLVMAVTANYPFALAPGMGLNAFFAFSVVIGLGIEWRVALGAIFIEGILFILLTLSQVRNKIIQGIPECLKQATAAGIGFFLAYIALSGDPATGGAGIIVANPVTITGLGNFQEPATLMAIAGIVITSAAVARRITGALLWGILATAILGWILGIAPSPQGIVAFPEFPTHLFGQAIGGLAGIRASNLWDFIAVTFVFLFVDLFDTIGTLAGVGVQGGYIRENGELPRATEALMADAIGTTAGAILGTSTVTTYIESAAGVAEGGRTGFTGVTIALCFVLSIFFIPLLQAVPGFATAPALVMVGVLMAGNVRRIRWDDPAESIPSFLTILVMPLSFSIAEGLAVGAIAYPLIKTFQGKARDTDLTQWILAGIFVLRFVYMAVTP
>NC_019693|1667210:1742727|1673479_1673632_-|WP_156823760.1|DBSCAN-SWA
MHETSTLGQTVKSNRWNAIPHLSCLMLFHGADWIEQVRRGDRHFRGTVQH
>NC_019693|1667210:1742727|1692785_1693130_+|WP_015147735.1|DBSCAN-SWA
MPILSHVERRAMEAVCKEFFPEGIPESFPEDFQDALQQAFHKGYQQGLQEGLQFVREIVLEVLNERFNPLPAEVIDRINQISDYETLKQVFKQRRSIGSVAEFEQVLAELMTDN
>NC_019693|1667210:1742727|1711957_1713994_-|WP_015147747.1|DBSCAN-SWA
MPEPTLELQQRIEQLRQQIQKASYAYYVLDNPIMEDSVYDRLYRELQQLEQEHPQFITPDSPTQRVGEKPATQFQKVRHNIPLYSLENAFNLQEFSQWQDRWQRIVSPLNFEYVTELKIDGSALALTYENGLLVRGATRGDGIEGEEITQNVRTIRAIPLRLNLENPPPLVEVRGEAFLGLDVFAKINKERAQSGEAEFANPRNAAAGTLRQLDSRIVAQRRLDFFAYTLQIPGIDDDDVAHTQWQSLELLQEMGFKVNPNRTLCQSLEAVESYYKEWDIKRKDLPYMTDGVVVKINSIPLQKQLGFTQKFPRWAVALKYPAEEAPTQIKAVTVQVGRTGALTPVAELTPVQLAGTTVSRASLHNSDRLAELDLHIGDTAIVRKAGEIIPEVVRILPELRPEGAQRFQMPTHCPECGQPVVKPISEAVTRCINLSCPAILRGVLIHWGSRDALDINGLGEKLVQQFVDRQFVNSVAELYELDVETLAQLERFGKKSAQKLVEAIAQSTQKPWSRVLYGLGIRHVGSVNAQLLTQKFPTVDQLSAASAAQIESVYGIGAEIANSVADWFQVPANQLLIDRLKAAGLQFAATPVTEKPASQSAAIFAGKTFVITGTLPTLKRDEAKALIQNAGGKVTGSVSAKTDYLLLGEDAGSKLKKAQDLGIKQLSEAELLDLLGQE
>NC_019693|1667210:1742727|1732053_1732794_+|WP_015147759.1|DBSCAN-SWA
MSSTTINNMKKILGISAAVSLGATVLPATSIAAPEGASLDIAQAQPAQAAPACREVEAEPGLNVRAQPWGEVIGSVGTNEYVYLQNPAPQDQDWVQIQSPMNGYVAANYLSYCTGAAAQQQPLTGVDPQGPISQQPGQMQPGQMQPGQMQPGQMQPGQMQPGQMQPGQMQPGQMQPGQMTGESCRAISADAGLNVRSQPEVGSEVITTLPDTTQVQIQNRGEDGWVPISEPTPGYVAAENLMMCGQ
>NC_019693|1667210:1742727|1735733_1736150_+|WP_015147763.1|DBSCAN-SWA
MGVCNTPLQSTHLDRARGYAVAIHGHPRYTKDIDIWIEMSSENADKIITALEQFGFGSLGLSAQDFQTPDQIIQLGYPPNRIDLITTPDGIDFETCYRSKTEVIVDDIPVQFIDLDNLKRNKKASGRLQDLADLENLE
>NC_019693|1667210:1742727|1735378_1735567_+|WP_044196627.1|DBSCAN-SWA
MEKVIHKTTKKEQTSDFQYWQNQPPLKRLEALEQIRREYHQYKYHAEPRFQRVYTVVKRQSS
>NC_019693|1667210:1742727|1688651_1689614_-|WP_044196607.1|DBSCAN-SWA
MVSKIDYSVVIPIFNEESIIPELWQRLAPVIKELGGYTEVIFVDDGSRDASLSLLTTIAQDSPHVKIIALSRNFGHQCALSAGIDRAEGQAVILMDGDLQDPPEAIFQFVSAWKQGYEVVYAIRKQRKESWLKRLAFKSFYRIHRVLSDIFVPLDAGIFSLMDRQVILTLRQMPERNKYISGLRAYAGFKQVGVIVERGYRYRGKPRVTLWKLFKLTFDSIFAFSTIPLRLATLFGFACATFSFAIGTIALYYKLVLNREFLSWAFGLTTTFFMGGVQLIFLGIIGEYIARIYDEVKQRPYYVIKQQIGFQDEPNFRIDR
>NC_019693|1667210:1742727|1715905_1716238_+|WP_156823763.1|DBSCAN-SWA
MKAIITRSPHYIPTFSPCTPSCPSSKPARTPLIRTQTFRDRTEIKGLTGIQTHALTGNRRKPFRFTPNQSKISGRETGYNKLSLPKSKHYTIYAKDFICGIARKRRKTIV
>NC_019693|1667210:1742727|1736426_1736618_-|WP_015147765.1|DBSCAN-SWA
MTMDNVTVKPETRNHKGFFVQEASYKLMGIEDSGWALICVENSCHYVDPDNLEADPELGDALD
>NC_019693|1667210:1742727|1674722_1676570_+|WP_015147723.1|DBSCAN-SWA
MTNSPITLAKEKKTVSKNGSTSNGSNVSGPTLKIIPLGGLHEIGKNTCVFEFEDEIILVDAGLAFPTDGMHGVNIVLPDMTYLRENRDKIKGMVVTHGHEDHIGGIAFHLKQFDIPVIYGPRLAMSLLEGKLEEAGVSDRTELRSVSPRDVVRFGKHFVVEYIRNTHSMADSFTVAIHTPVGIVIHTGDFKIDHTPVDGEHFDLQRLAEYGEKGILCLISDSTNAEVPGYTPSERSVYPNLDRVFSQAEGRILVTTFASSVHRLNIILDLAKKQGRTVAVVGRSMLNVIAHARNLGYIKCEDSLFQPLHAIRSLPDNKVLILTTGSQGEPMSALTRIANGEHRKIKIRKGDTVVFSANPIPGNTIAVVNTIDKLMIQGANVIYGRNQGIHVSGHGCQEEHKLMLALTRPKFFLPFHGEHRMLVQHAKIAQSMGIPAENMVIINNGDMVGLTTDSIGVIDQVPSGIELVDASRSGVVKDEVLKERQQLAADGVVTIAAAIGWDGKLAADTATHLRGVVSSIDPNLLKKWIGQTIEGVLSDRWSEFSRTLEDGTPEVDWTGLQNQLERDVQRMLRRELQSNPLLVFLMQNPQEPPTVQEQPATTGRRRTRSTAKVAS
>NC_019693|1667210:1742727|1704358_1706386_-|WP_015147743.1|DBSCAN-SWA
MVRVTHTGEDTRTELRDRQWSLVILDEHLRHPSPAELLKQIGNKGQSSPPIPVIYCGVKGIETYPIAPSGKGRKPKEPRNSSTTKQQSETLDRVTCFLYHPLDGEELAREVAKLLNLNLSDPQPSAKQDPTIVAAIGKVWERFKDRIAERVTAIEQATEALNYGELPPELHATAKQEAHKLAGSLGTFGLTEGSVIARQVEQLLHSPTLDATQCGNLTGLVQALRSQIDQAPVKSDRREGSPLNDLPVLLMIEGDQELSHQIGVEVKGWGIKVVNSDSISSARTAIAHRRPDAVLLDLSTEETLTINPNNKEEGLTLLSELANGFPPLPVLVVTDQSRVEDRLEVARLGGRAFLQKPVRPAQIMEAVLQILQGVQTTEAKIMVVDDDPQILSLVKHFLEPWGMKTIALSDSQRFWETLEVSSPDLLILDIELPHLNGIELCQVVRNDPRWNSLPVLFLTAHTGPDIVHQVFAAGADDYISKPIVGPELVTRILNRLERIQLLRNMAETDPLTGVANRRKSITEFDKFLHLCQLNEQPMCLSMVDLDRFKQVNDRHGHAMGDAVLRQFGKLLLRTFRSEDIVARWGGEEFVVGMYGMNKESGSKRLSELLQILHAEPLIIGEERLYLTFSGGVAQYPEDGKTVDMLYRCADQALYQAKTAGRDRIIAYHHSTDEPG
>NC_019693|1667210:1742727|1737820_1739482_+|WP_015147767.1|protease|DBSCAN-SWA
MKWSRTGLSAAILGVGAVILVAKAPISLPQTQGIEEQAISAMGREVSVVINGQNPGSGVIIARNGNTYTVLTAKHAIATPDEYAILTPDAQTHPVDYGTVKKLPGVDLAVVEFTSPNPYRVAHFGNSDDAMEGATIYVSGWPHPGRVITERIYQVAKGTISGRPLTALEDGYGLIYTNITRSGMSGGPVFDNQGRLIGIHGRAEGEAIYNPDTGDTVDVKSGFNVGMPINTFVSLAAEAGINVPRLGDNFTAASLTLPAHSALVLAVAVAPDNQTIASGSRDGIIKLTNGNSGQEIRTLTGHTDAVTALTFSPDGQTLVSGSEDGTVKIWNRQSGELVRSFQGDRSFVRALAFSPDGTLLASGSAEDTDIKLWNPQTGDLIRTLTGHRDYVNTVAFTNDGQLLVSGSTDKTIKLWNPESGEAVQTLTGNANRITSVVTTPYGNLLAAASAEDGLVKVWNLRTGELLHTLTGHRGTVYSIAIDPYGHILASGGIDGTIQIWNLYTGNRVRNLEVINSGSGHQSPVFSLAFSRDGQTLVSGADNGKVQLWQIPQR
>NC_019693|1667210:1742727|1733127_1734054_+|WP_015147760.1|DBSCAN-SWA
MKIAIAGATGFVGSRLVEKLQQAGDQVLILTRNPTKAKRVFPDAAFPNLEIIAYTPTESGPWQQALSGCDGVVNLAGAPIADERWTPERKQEILNSRKLGTRKIVEAIATANPKPSVLVNASAIGYYGTSETATFDETSASGNDFLAQVCQEWENEAQQVKQSGTRLAIIRSGIVVGNGGAIAKMLTPFRLLAGGPLGSGHQWFSWIHREDLVTLILLALHRSDIQGILNGTAPNPVRMNELCHILGQVLHRPSWLPVPDFALQLILGEAAQVVLEGQQVLPKRPLEYGFEYRYPTVKPALEEVVSHG
>NC_019693|1667210:1742727|1725700_1727431_-|WP_015147754.1|DBSCAN-SWA
MQVQPMVTEYFAKQDYEGAVALCRQNIQAQPQVIVNYWYLGVALLLQGKQTEAEHCWNAVFSQGTPPQVQQWRQQLYQLLGAIANQRESVKDWESALVLRDRIEAIAPHDINNHLARLQLYLHLGLIDSTLTERLITTAELLLSSNYSNLNQPLLIAVLRQLAEGQVFHVKSLQLLEAAVTQNLLNHPDWNQNIRLQQTYGNYYRNKALKHCDYGEFPEAILSFWKAQDLVPEISITYPLAMAFFAQGKLSEAAELLSQISDKQPEYASARYILSAIYTPQSQEVLRTIYQRVIEKSWANCKYPQAANAAQKMVELEPGSSHAQYNLGMSLYYEGLFTSNVEKVYQAELALKKALEFKPNNEILHKKLSTIPYTLQFAQKGYNVSADCFTGVMPIWEQNFRKYANMPNLRVVEVGCFEGMASCWLLDNILTHETARITCIDNFEGVVESKKNDPTVQKSVEERFDGNIEKSGAKHKVDKRVGFSQEVLRSLPLNFYHIVYIDGSHFAIDVLQDAVLSWGLIKEGGMIIFDDYHFEFPDRPHCNTGRGIDAFMTVFQEKLKVIYRDDRQIFLEKLSH
>NC_019693|1667210:1742727|1693681_1697059_+|WP_015147736.1|DBSCAN-SWA
MNELRKIAYIKLIQSLLSCPSGKQVKILSAHPELIDEGLVEMMRVVAEMTGEQGQRNAGWLRNLAGKIETANYSLPRLQTKLAADTLLQQGLQQYQQSQYPRAFQSLQRCLALYQTIGDKARMATAWRVLGDIEQRRGNWDEAERLFRQSLQLSTELGDRCGMATSWGQLGDIEQRRGNWDEAERLFRQSLQLSTELGDRKGIATSWRVLGDIEQRRGNWDEAERLYQQSLELRIELDDRSGMASSWASLGDIQRNWGNWDEAERLYQQSLALRIELDDRSGMASSWASLGDIQRNWGNWDEADHLYRQSLKLSTKLGERSSIANSWGQLGNIEKLRGNWDEAERLFRQSLELSTELGEPFSMANSWGQLGDIQRFRGNWDEAEHLYRQYLEVMTKLGERFGIATSWGVLGNIEKLRGNWDEAERLFRQSLELSTNLGERSRMATAWGELGDIEKLRGNWDEAERLFRQSLELSTNLGDKSGMGDSYNDLAIVHTHFNQIPEAIAAWRKGLAVCPPNRFPLEALELGRSLGNTAFDIEEWETAIEGYEAAIEAVETLCSFTDSYTEKQKRREAEISVYEKLVQACIHAEEIGKALASVERSKSRNLIELLVNANLEPTGNIPEEMRQELDRLRREVTAKQRILESLDNPLNSNLVSDTDFGQRRSESPNFNPTAIETIREQYIAAKQALNALLDRLKAYDPNFTLTQRVEPIQFSEIQGLIDEKTALIEWYLTRDRIYAFVVTGGDGKISHWESTPTQYTDLQQLCQTYLDAYFSNKSQWKTDLDGFLQRLSDILDLPQLIARIPSDYRQLILIPYRDLHLFPLHALAINRATAPHYLCDRFPDGVKYAPSCQFLQVSQRNQKSESQNRFFAIQNPTGDLTYADLEVEAIFPAFHPNASCLTRQQATKLALSQHPYEADFRSAEYLHFAGHGGFNFTNPLDSFLVLAGAVAGGENNSGRDPERFVSWRKGESVELEKCYTLGELFELNLPYCRLVILSACETGLIGVSPDLEEYMSLGLGFLYAGAQNVICSLWAVNDLSTAILMVKLYEELQTQSSVSQALNQAQQWMRSVTKRALIQWLDELSLEKEVKDSLRKNLPRLGLKPPEYRPFEDRHHWAAFCAIGI
>NC_019693|1667210:1742727|1669516_1670941_-|WP_015147720.1|DBSCAN-SWA
MKVTQEKLPASKLGLEIEVTPDMSQKAYEQVIQQFSRQASIPGFRKGKVPRSVLVQRMGTSRIKAAAVEDLIQNSLEKIVKDEEIPALGNFQLISSFDELVTKYEPGESLVFSVSVDVPPEVTLNEYTGLAIRAEEIKYDPAEVDQFLEERRKEQATLIPVEERAAQAEDVAIVDYVGKIINEEGGEPEPLPGGEAENFQIELSEGRFIKGFVEGIIGLTVGETKELNVPFPEDYPNEDLAGKEAIFTITVKELKEKELPELDDDFAQAVSEYQTIAELRESLEKQYQEKADRETKANKHAALVEAIEKVVEVELPETLIDRELDNILQQSMMQLANYGIDVKKLYTKETVAALRQQSQPEAIANLRKSFALKEVAARESLSVTAEEVNARIEELKDRLPPDFDRDRLISALESEMLKEKALDWLEERAQIELLPAGTLEAEAAAAAAAAEAELAEGEESVGEVVEVEAIDSPE
>NC_019693|1667210:1742727|1697160_1697601_+|WP_015147737.1|DBSCAN-SWA
MKESTETFLMLAQLLETEPPILQREALSQVQQLAEQLDRVPEGDEEKAAAVIIDWSAQFPQEQETLEKAVSKAGLKKERKELDEILENHPRYGQWIVPNFEIIEEPETQRDLVIITPEPPQKQTPAKMSPLLYLRQSLQQWIHKNQ
>NC_019693|1667210:1742727|1668561_1669251_-|WP_044196597.1|DBSCAN-SWA
MLISQTPYYPISGSESLEIASTSQNVIPMVVEQSGMGERGFDLYSRLLRERIVFLGTPVDDNVADLIVAQMLFLDAEDPEKDIQLYINSPGGSVTAGMAIYDTMQQIRPDVATICYGLAASMGAFLLTAGAKGKRMSLPSSRIMIHQPLGGAQGQAVDIEIQAKEILYHKRQLNEMLAFHTGQPLERIEADTDRDFFMSAEESRAYGLIDQVITKQGLPKSGEAVTAQK
>NC_019693|1667210:1742727|1714057_1714756_-|WP_015147748.1|DBSCAN-SWA
MPNNSILKSEHLYKMYGQKNLNFVQAVEDVSLELKAGELVLISGPNGSGKTTLLSLLGCMGKPTEGTIKILDCEVTCLSQTALTDFRLKNIGFIFQTFRLLNFLTVLENVKLILNLAGKTGVAAHQRAKFLLEELNIAHRANFFPPALSGGEKQRVAIARALANDPALLLADEPTGSLDYQTGQSVIQLLSNVAKTHQKAVAVVTHDPRIEHYADRILTMEDGHLTPKTNCS
>NC_019693|1667210:1742727|1693218_1693458_+|WP_044194647.1|DBSCAN-SWA
MPILSNIERRALETGRHEGRREIVLEVLNDRFNPVPLAVIDRINQISDLATLKQLLKRGISIGSLAEFEEVLESMRTHD
>NC_019693|1667210:1742727|1741227_1742727_+|WP_015147769.1|protease|DBSCAN-SWA
MSQDFVNFNPTVVTIAIAGMMGVSMPVAIAQLNQQQVSAMAEQVTVLIQGQNPGSGVIIGQSGESYFVLTAKHVVATQDEYYIVTPDQQQYPLDYQRIHKIPEADLAVVQFTSDRSYDLATIGNSDQVIQGNIIYVAGWPHPGEAITERIFQLTTGTVSGRSLSGTSDGYELVYTNITRSGMSGGPLFDQNGELIGIHGQSEGQNIYNPDTGDMVSVKAGFNLGIPLATFMQLSAPNPLPPNPSFANPLTHAAIQALGENRVADAIGLYKRATEVNPEYLEAVFGLGQAYYESGDRNMALSQFEKAVELTRAEMERLRSLGTVEVLAYNNQVNVELALGTLLFTSGDRLEGLNLLVGLLQYNNQMVREKLFQPDFASSRLRSDAVPLQHYGEKILSTEAGKLPPEFNQGQVLYELGQVQAAIPYFQIILDKYKNDPRVMLALAVALQETGQSDRADVLLQEIQTEQSQETVSWESGGWLGIFWSDRLIEKARPLIPPQT
>NC_019693|1667210:1742727|1716200_1717898_+|WP_015147750.1|DBSCAN-SWA
MELPENAAKQSFEFDSIEEALAEIAAGRSIIVVDDENRENEGDLICAAQFVTPEIVNFMAVHGRGLICLAMTGDRLDQLDLPLMVTTNTDTNQTAFTVSIDASPQQGVTTGISAEDRARTIQIAINPHTKPKDLRRPGHIFPLRATSGGVLKRAGHTEAAVDLSQLAGLYPAGVICEIQNPDGSMARLPELIEYAAKYNLKMISIADLIAYRLQHERFVIRETEAALPTEFGQFRIYGYRNTLDNKDHVAIVKGDPANFTNKAVMVRVHSECLTGDALGSLRCDCRMQLQAALKMIENAGEGVVVYLRQEGRGIGLINKLKAYSLQDMGLDTVEANERLGFPADLRNYGVGAQILNDLGVSRIRLITNNPRKIAGLKGYGLEMVDRVPLLIESNPFNCTYLATKAEKLGHMLLQTYLVTVAIHWQEPELEEGPPAQVQAWYEHLEKIRELADEHHLVLQEEKRPVTVALFGKPQLTFHLGFDQAHLATTDWFTHPEHPYVQATFRILDRLLLWPDIDQLQFLVSTGVDPLTNLGVQLQRQSFPLSKMPSQLCDSLHTQVIYCFKG
>NC_019693|1667210:1742727|1703109_1704045_+|WP_015147742.1|DBSCAN-SWA
MNDQLRERGDNGGYAQTEGELPARLDNLKSQLVNFTVRDSEGQPLGRVMDLTIEPENQLNLIVSLVDDRPGRLVKVSSDLFEKIEYATNTVFVLLTRQHFAALPEYQTPAYSGEIDPSELPGEWVESVPSAGSSGTIALEQRSHQIDSQSSLADFKQIRKEVIASNIPLHEERLVVNRHKRKVGEVVVRKEIETRMIQVPIRREKLIVEQVSPEYKKLTEIILGEGDGYRLGSDEAPGITPTTASLMPQGQGTNRVSGEFHSPEIAARILEEISKRQPNGCVKVRVELVVEEERFRNTYQSWFDRYSTPQS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015147718.1|1667210_1668551_-|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.1e-137	57.2
WP_044196597.1|1668561_1669251_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.1e-53	56.1
WP_015147720.1|1669516_1670941_-	trigger factor	NA	NA	NA	NA
WP_015147721.1|1672273_1673329_+	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_156823760.1|1673479_1673632_-	hypothetical protein	NA	NA	NA	NA
WP_044196599.1|1673716_1674607_+	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_015147723.1|1674722_1676570_+	ribonuclease J	NA	NA	NA	NA
WP_015147724.1|1676762_1677458_+	DUF1131 family protein	NA	NA	NA	NA
WP_015147725.1|1677547_1678504_-	DUF3578 domain-containing protein	NA	NA	NA	NA
WP_015147726.1|1678845_1679343_-	hypothetical protein	NA	NA	NA	NA
WP_015147727.1|1679339_1679636_-	hypothetical protein	NA	NA	NA	NA
WP_015147728.1|1679723_1683707_-	magnesium chelatase subunit H	NA	NA	NA	NA
WP_015147729.1|1684313_1685912_+	hypothetical protein	NA	NA	NA	NA
WP_015147730.1|1685991_1686468_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_015147731.1|1686536_1688333_-	hypothetical protein	NA	NA	NA	NA
WP_044196607.1|1688651_1689614_-	glycosyltransferase	E7C9N8	Salmonella_phage	4.2e-54	40.1
WP_156823761.1|1690011_1690149_-	hypothetical protein	NA	NA	NA	NA
WP_015147733.1|1690290_1691565_+	hypothetical protein	NA	NA	NA	NA
WP_015147734.1|1691735_1692698_+|transposase	transposase	NA	NA	NA	NA
WP_015147735.1|1692785_1693130_+	hypothetical protein	NA	NA	NA	NA
WP_044194647.1|1693218_1693458_+	hypothetical protein	NA	NA	NA	NA
WP_015147736.1|1693681_1697059_+	CHAT domain-containing protein	NA	NA	NA	NA
WP_015147737.1|1697160_1697601_+	hypothetical protein	NA	NA	NA	NA
WP_015147739.1|1699415_1700066_+|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_015147740.1|1700157_1701573_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	5.1e-48	29.8
WP_015147741.1|1701972_1702851_+	DUF2382 domain-containing protein	NA	NA	NA	NA
WP_015147742.1|1703109_1704045_+	DUF2382 domain-containing protein	NA	NA	NA	NA
WP_015147743.1|1704358_1706386_-	diguanylate cyclase	A0A1J0GWE0	Alteromonas_phage	1.5e-08	28.4
WP_015147653.1|1706498_1708076_+|transposase	IS1182 family transposase	NA	NA	NA	NA
WP_015147744.1|1708114_1708897_-	response regulator transcription factor	W8CYM9	Bacillus_phage	3.5e-35	38.0
WP_156823762.1|1709871_1710045_+	hypothetical protein	NA	NA	NA	NA
WP_015147745.1|1710083_1710566_+	ATP synthase F1 subunit epsilon	NA	NA	NA	NA
WP_044196617.1|1710769_1711735_-	DMT family transporter	NA	NA	NA	NA
WP_015147747.1|1711957_1713994_-	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	2.5e-112	36.9
WP_015147748.1|1714057_1714756_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.1e-39	41.7
WP_015147749.1|1714758_1715859_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_156823763.1|1715905_1716238_+	hypothetical protein	NA	NA	NA	NA
WP_015147750.1|1716200_1717898_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase RibB/GTP cyclohydrolase II RibA	A0A2H4PQS2	Staphylococcus_phage	2.6e-99	47.5
WP_015147751.1|1718438_1721876_+	PAS domain S-box protein	NA	NA	NA	NA
WP_015147752.1|1722097_1722556_+	response regulator	NA	NA	NA	NA
WP_015147753.1|1722589_1725271_+	response regulator	W8CYF6	Bacillus_phage	6.7e-25	29.4
WP_015147754.1|1725700_1727431_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_015147755.1|1727682_1728849_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_015147756.1|1728929_1730015_-	class I fructose-bisphosphate aldolase	NA	NA	NA	NA
WP_015147757.1|1730325_1730946_+	HPF/RaiA family ribosome-associated protein	NA	NA	NA	NA
WP_015147758.1|1731294_1731840_+	hypothetical protein	NA	NA	NA	NA
WP_015147759.1|1732053_1732794_+	SH3 domain-containing protein	NA	NA	NA	NA
WP_015147760.1|1733127_1734054_+	TIGR01777 family protein	NA	NA	NA	NA
WP_015147761.1|1734418_1735003_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_044196627.1|1735378_1735567_+	hypothetical protein	NA	NA	NA	NA
WP_015147763.1|1735733_1736150_+	hypothetical protein	NA	NA	NA	NA
WP_015147764.1|1736149_1736401_+	hypothetical protein	NA	NA	NA	NA
WP_015147765.1|1736426_1736618_-	hypothetical protein	NA	NA	NA	NA
WP_015147766.1|1737160_1737814_+	hypothetical protein	NA	NA	NA	NA
WP_015147767.1|1737820_1739482_+|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_015147768.1|1739508_1741212_+|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_015147769.1|1741227_1742727_+|protease	serine protease	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NC_019693|3444735:3506658|DBSCAN-SWA
TATGTTTTGGGCTGACAAAATTGCGGAAAGTGCACAAGGCGAACAAATCGTTAATGATTCAAAAACCCCTTCGGGTCGAGTTCATGTGGGGTCCTTGCGGGGTGTGATTATCCATGATGTCATTTATCGCGCCTTGAAACACGCCGGTAAGCCCGTAAAATTTATGTATGGCGTTGATGATTATGACGCCCTTGATACCGTTCCCGGTTACCTCGATCGCGAAAAATTTGCCCCCTATTTGGGTTACCCTCTGTGTAACGTCCCCTCCCCTGATGACAAGGCGACAGATTACGCCAAATATTTCATGGGGGAATTCCTAGAAGTCTTTGATTACTTAGGGGTAAAACCGGAGATTTATTACCTGCGAGACTTGTATCGAACGGGACAACTCAACCCCTATATTGATACCTTCTTGCAAAATTCCCATTTGGTTCGGGAAGCCTATAAAGAAGTTAGTAAAGCCGATCGCCCGAGTAACTGGTATCCCTTCCAAGTCATCTGCGAAAACTGCGGAAAAATTGCCACCACTGTTGTCACCGACTACAACGGCAAAGAAGTCTTTTACACCTGCGAACCCAACGCCACCAACTATGTCAACGGATGCGGACATTCCGGCTGGGTTTCCCCCTTTGATGGCAATGGCAAACTCCCCTGGAAAGTGGAATGGGTTGCCAAATGGCAACTGGTAGGGGTTACTATCGAACTCGCTGGAAAAGACCATTCTCAAAAAGGCGGTTCTCGCGATGTTGCTAACGCGATTTGTCGCAAAGTCCTGAAAAAACAACCTCCATTCCATTCTCCCTACGAGTTTATTTTAGTGAATGGAACGAAAATGAGTTCCTCTAAAGGAGTCGGTTCGGCAGCAAAAGAAATCGCCGAATTGTTACCCCCGGAACTGCTGCGTTTCTTGATGCTGCGAACCCAACCGAAATCGGTGATTAATTTTGCCCCGAATTATGAAACCACCACCCGATTGTTCCGGGATTACGACACCTTAATCGAGAAATATCAAGGGGTGACTCCGGAAGGTGGGGAAGACCCCAAACAGGATAAAGAACTGCAACCCCTGTTTTATTCTCAGCTAACCGATGAAGTCAAAACCTATCAACCCTTTGATTTCAGCACATTAATTTCCCTGCTGCAAGTGCCTCATTTGGATATTAAAGAAGAAATCCAAAAACGCTGCGAACACCCGTTAACCGATGCGGATTGGAAAGTTCTCCATCAGCGGATTGAGTCAGCCCAAAAATGGCTGGATGATTATGCCGATGAAGAAGAAAAACTGGTGCTTTATTTTGACACAATTCCCGAACAAGTCCAAGAGTTGACTGAGGAACAGGTGACTTATTTGGGTGAGTTAGCCAAGAATTTAGAAGCGGCAGAGAGTTGGGATGGGGAAACCTTACAAACGATTATCTTCTCGACGAGTAAAGGGTTGGAGATGAAACCGGGGAATGCGTTTCCGGCGGTTTATTTATCCTTCATGGGTAAGTCCCGAGGTCCGAAAGCGGGGAATTTACTCTCGTATTTAGATAAATCGTTTGTGTTGGAAAGAATTCGCGGGGCTGTTGCGCTGAAACAAGGGGCGGCTGTGTAGTAGCGACAACCGGCGGGGGATCAATCCCCCGCCTAATAGCTAAAGTCGGATAAATCCGACTGAAAACTATGGATTAAACCGCCATTATTGAGAAGCTAAAACTATCAAAAATAAGGCTTTTAGTCGGTTTTTAACCGACTTTAGCTGTTAGTCGGGGGTTTTAACCCCCGGCGGTTGTCGCTGCTGCGGTTGTCACTGCTTACGACTCTTGTAACGCTTTCAATACCGTGTCGTGGATGGTGCCATTGCTAACAACGATGCCTTGATTGTTGACCATTTTTTTACCCATCCCAAAGGGTAAAGAATTGCCATGCATATCCGTGACACGCCCTCCCGCTTCTTCAACCACGATCGCCCCGGCGGCATGGTCCCAGATATTCTCTCGGTAGTCTGGGGTTTTGGGAGAGGGTAAGCGCATATATAATGCCGCTTGTCCTGATGCGACAATTCCATATTTGGCTTGGGAATCCATTCGCACAGATTCAGCGGTGAATCCGACGGCTTTGGCGACAGAAGTTTGCCTGGATTGGTCGCCGTGACTGGCTTCTACGCTTTCTACAAACCGCATATTTTCCACATCATCAGCGGCAACGACTCGCAACGATCGCCAGGTTCCGCCCGAGATTGCCTGCATTGTTGCCCCTTCTCCCCGGACGGCTACAAATAAGGTCCCCTCTTCTCCCGACTCTAAATTAAGGGCGGGACAAGCCATAACGCCGACTTTCACCTCGTTGTCTTCAATTAAGGCGATCGCCACGGCATATTGATCCTGTCTCAAAAATCCTTTAGTCCCATCAATCGGGTCTAGGGTCCAAAATCTTCCCCCAACTTCGCCATTGCCGCGATCGATCCAATCGGCAACCTGTTCCGGCGTCGCATCGGGAACCAGGGACTGGACATGATGCGTGACTTTTGTCAGTTGTTCGGAATTGCTTCGCAGATCCGTCGCATCTTCTTCCCCCACGATCGCATCTTCGGGAAATGCCGCATCCAATGCTTTGCAAATCAACGCCTGAGACCCATAATCTGCCACGGTGACGGGGCTTTTATCAATTTTTTCCATAGCAACCGGAATCTCCCGGCGTACTGCTTGGCAAAGTTTAGCAGCCGCGATCGCCGCATCAATGGCAACTTGTTTTTCCCGTTCGTATGACATCCTAAACCTCTTCAAACAAATAGAGACGCGACGTCGCGTCTCTACAAACTTTAGACTCTTGCTAATCCCAAGTCTAGTCAGATTAAACGATAAACAGCAAAACGATTCCGCCGATGATCATTCCGCCACTCATCAAAAAGGACCAGAAGCGATGATAACTGTTCACCTTTGTCTCATTCTGGGTTTCTAACTGGATCAAATCCATCCAGGGGGCGACTCCCCGGCGAAACCAACCCAAGGTATGAACCTGCATTCCAATCAGGCTTTTCACCTTCTTCATGCCAAATAGGAAATTGCCAATCGGACCAAATCGGGAGGCATAACGCAGAAATAGCAATCCACTGGGGTCTTGCAGTTTCAAATCGGACCCGAAAGTATATCCCGCATCTCCCCGTCCAATCAATTCGCCTTTGAGTTTAGCCGGTTTACCCCGCAATGGACTGGCGTAGGGGTCCGCCATTAAGGTGAGAATATCGGTTTCTGGGGCGCGATCGAAGTTGGGGAACATGACTAAGGTTTTCACCAAGAGGCCAATTCCCAAGCCCAGTAAGGGATAGGCAAGAAGCGCAAAGTCTCCTGGGGGTATGGGTAAGACGAACCAGGCGATCGCCCCTGCAATCAATCCAATCATCGGGGCCATATAGAGGAATAAATCCCCGACAAAAGTGCCGTATAGCTTACTCTTACTCAGAGTCCGACCTTCTCCCATAATCCGCCCCATGTCGAACTCGATGTCTAATCCTAACTGTTCGGCGTAGGTACTTAAGGCGCGAACCCGCTTGCCGGTTAAGGGGTGAGTGGAGTTCAACTCCATCCACCATCCCCAGGGATTAAACATATCCCAAAGAAACACTCGCCCAATTTGTTCGGGTTTGCTGGAAATTCGATAGGTAGTGCCTGTGGAGGTGGCGGCTTTATGGTCGTAGATGCCTAATGCCCGAGTTCCTTCCACTAACCGACTGGGTTCTGTGGCTTTTTGCCCTTCTTCTACTAACCCATAAGCAATTTTAACCAGTGCCCGGGAGAGGGCGTTGGGGTTGCCGGTGGTTTCTGCTGCAAAGCGATCGGCAAAATATTCCCGAGTTCGCGAGAGGTACAACAGCAAATAAGTACCCACCAGATAAAAAATGTAGGCAGCCATTGCTACTTGACCAGCTATATCCTTGGCTTTTCCCCCCCCACGTCCCATCCGACTGGCATACACATAAATCAAATAGGTAATTTGAACTAAGGTGGAGGCGACTGTCATCACCGCAAAGTCCCAATGGACGATGTGACCCAGTTCGTGGGCGTAGACGGTGGCCGTTTCATCATCATCAAGATAGGTAAAGAGTCCCTCGCTGACGACTAAACGGGCGCTATTGGGGAGAGACCCATAGGTAAAGGCGGTGGGGTTTTGGTCGTCGATAATCCCCAAACGCGGTTGTTTCAGATTTTTGTCGGCACAAATCTGGCGGATAATTTCTGCCGACTCAGGACTCTTGCGATTCAGTTCCGTGAGGTCGATCCAGCGAGTCCCATACAGCCACTGCTGGGTTAAATCCATAATCCAAGGGGATAGGAAAAAGGCGGCGATATTAAAGACGAGGGTACCCACAATTGAGATCACTAAGCCCATCCCTGGATTCTCGCTGTTGAGAATTAGGGAAACGCCTAAACACAACACGAAAACCATCCCAAACATGAGGGTCATGGTAACGACTGAAGCAAAGGCGAGATTGCCTCCAACTCCAGTCATCATCAGCTTAACGCCAGTAGTACCGCTACGTCCCGCTTTCGGGAAAGAGGTTTCAGACATAAACACTCTCCATGTCACGATTACACAGTGAACAGGTTCTAAACACCCAAAGCTTGGTAATTTAGTCAAGCCCCTGGGGAAAGTTTTCTATCCTTTCTGTCATAACCTACAAGTCCGGGTTTTTGGTCTAAAACTCCACAAAAGTTAAAGAATTGGCTATAGCATGAAAAAAGTTAAGACCGTGGGTTAAAGTCAACCTTTCCTTGGTCGTTGGTCGTTGGTCATTGGTCATTGGTCATTGGTCCTTGGTCATTAGTTGAGTATTCAGTAATCCAAAGGACAAAGGACAAAGGACAAACGACCAATGACCAACGACTCGCCCGCCCAGATTTTGGGGTCTAGGGTTGGTGTCAAAAACTACAGTCTTAACGGGCAAATCTACGGGATAAAATTACAATGACATCCATGCAAATTGGTTCGGAAAATCTAGTTACAATTGCTCAATCCACGGCGATTGCTGCCCGGAAATTGGGGATACTCTCCACGGAGGCGAAAAATCAGGCGATCGAGGCAGTCGCCCAATCTTTACAATCTGCTGCCTCCGAAATTGTTGCTGCCAATGCCAAAGATTGTGAAATTGCCCAAGCGGATGGCATTTCCAAACCCCTTTACAACCGTTTAAAAATGGACCGGACCAAACTAGAGGCAACCATTGCCGGAGTTCGAGATGTGGGGAAACTCCCGGATCCGGTGGGTGAGATTCAGCTTCATCGGGAATTGGATGAGGGCTTAATTCTCAAGCGAGTTTCTGCACCATTGGGGGTGGTTGCGGTGATTTTTGAAGCCCGTCCCGAGGCAGCAATTCAAATTTCTGCCCTAGCGATTAAATCGGGCAATGGAGTGATTTTAAAAGGCGGGAAAGAGGCGAATCATTCTTGTGCAGCCATTGTTAAAGCAATTCGCCAAGGGTTGGCCCAGACGGAGGTTGACCCGGATGTTGTGCAGTTGTTAACGACAAGAGAAGAAACGTTAGCGTTATTAAAATTAGATAATTTTGTAGATTTAATTGTACCGAGAGGGTCAAATGAGTTTGTGCGGTTTGTTCAGGACAATACTCGCATTCCGGTTTTGGGTCATGCGGAGGGGATTTGTCATTTGTATGTAGATGCCTCGGCAGACATTGAAAAAGCGGTGACGATCGCCGTTGATTCTAAAACTCAGTATCCGGCAGCTTGTAATGCGATCGAAACCTTGCTGGTTCATGAGGCAGTCGCCCCAGAATTTTTACCCCAAGTTGCTGCTGCACTCCAAGGGCGTCAGGTGCAATTACGGTTGGATCAGAAAAGTCAAGCTATCCTGAAAAATACCCCCAATTTACAGGATTGGGAACCGGCAACGGAGGAGGATTGGAAAACCGAATATACGGACTTGATTTTATCGATTAAGGTGGTCGATTCTTTAGAAGAGGCGATCGCCCATATCAATACTTATGGATCCGGTCATACCGATGCGATCGTCACTGAAGAACAATCGGCTGCAAATCTGTTTCTGTCTCAAGTTGCCTCTGCCGGAGTCTTCCATAATTGTTCCACCCGCTTTGCTGATGGATTCCGCTATGGTTTCGGGGCTGAAGTGGGAATTAGTACCCAAAAAATGCCGCCCCGAGGTCCTGTTGGACTAGAAGGATTAGTCACTTACAAATATCAATTAGTCGGCAAGGGTCAAGTGGTGGCAACCTATTCCGGTCCCGAGGCTAAATCCTTCACCCATCGTAATTTAGCTTAAGACTGAGAGGGGAAAAATAGGTTTTTTCCTCTTTAAAAGAATGTAGAGGCGATTCGCGAATCGCCTCTACATTTCGGGGTAATGTAAAAACCCTGAAAATCATCAATTGTTCACCTAAAATTGCACCATTAAATTCTTTCAGTAACGGCATGAAAGTATTCACAAAAGCTGCTCTCATCCGAGTAGCAGTGTTATCACTCATCGTGATTTTTGGACTAACATTAGGCTGGAATACCGTGATTAATATGCCTGGAAAAAGTTATGCGGGAGACTTACCCCCCTTAACTGAACGCGAACAAGCCTTGCAAGTTGAACTCCGCCAATCCATCGAAAACATTGCCGGAGAAGACATTGGCGAACATAACTATTTTTACTACAATCAATTAGAAGCGGTTGCGGATTGGATAGAATCGGAATTTACCGCTGTAGGTTATGAAGTGAAACGACAAACCTATGAAGTCAATGGGCAGCAGTTTCATAACTTAGAAGTTGAAAAAATTGGCACCAAAAAACCCGAGGAAATCATCGTGATTGGCGCTCATTATGATTCGGTGGTGGGGTCTCAAGGCGCAAATGATAATGGCAGTGGAACCGCAGCGGTATTAGCCATAGCCCGGGAATTTGCAGACAAATCAACGGCGCGAACCTTGCGATTTGTAGGATTTACCAATGAGGAACCGCCGTTTTTTTGGACCGAAAATATGGGCAGTTTTGTCTATGCCAAACGCTGTCGCGATCGCCAGGAAAATATTGTGGGAATGCTCAGTTTAGAAACAATGGGCTACTATTCTGACCAGCCCGGTTCTCAACAGTATCCCCTCGGATTATTAAACCTCGTCTATCCCATCACCGGAAATTTTATTACCTTTGTCAGCAATCTCCCCTCGGGAAATTTCTTGCGAGAGGTGATTGGTTCCTTCCGCAGTCATACCCAATTTCCCTCAGAAGGTGCAGCGATGCCAGGGGCAACACCCGGGGCTGGTTGGTCGGATCATTGGTCATTTTGGCAGTTTGATTATCCCGCCCTAATGGTCACCGATACCGCCCCCTTTCGCTATCCCTTTTATCATACGATGCAAGACACCCCAGATCAAGTCAATTATGACCGCCTCGCCCGAGTGGTATCCGGTTTAGAACGGGTCATCGAAGAACTCGCCCAGGGGAGAATTGCCGCGTCGATTTAATCCCTTCAGGTTCAAAGTGGATTCTTTGGACCCGCTTTGTCGTTCTGTTCGGCAGTTTTATCCCCTCAATCCCCAGGCGTGAATCCGATTATTTCTTAGCAGCAGTAGTTGCTTTTTTCGAGCTATTATATTGATAGGTTAAATCATCAACGGTCCAAACTTTATCTTGTTTAACCAGTTTCATTTGCACGAGAACTTCCCGACCTGTTTTAGAAATCACGGTGACATCCAGACAGTGAACATCCTCCTCAGTCGTGGGAATTGACATGGTAGTGCGCTGATACTGATTTAGTTTGTGGGTTTTGATGAATTTAGCAAATTGTTGTTTAGAGGTTTTGCTTTTAAAGCGATCGCTGGTGGACTGATAGGCCCCATTGATATCCCCTTGGCCAATTTGAGCAAAAAAGGCCCCGATCGCCTGGGGTAATCCTTTGGTTTTGGAAAAAATAATCAGGGAAACGCTAATCCAAATCAGGACGATTCCCCCGACGATGACACCTACTCCAATTCCCACATACGATAACCAAGGTTGAAAGGATTCCACAGTACACTCCTAAACTGATCAATGAAATGACAAAAAAATCATAGGGTGAAGGGTTATCCCCACAAACAGATCCCCAAAGGGGATAACCCCTGTCTGGTCTTACCATAAAAAAGCCCCTAGAGCAAGGGTTCCAGCTTAGGAGTGGGGAGTCGCCGGCAGTCGCAGGGACTGTCTATAACTGCAAAAATTCCCCTGAACTTTAGGGGACTGAATCCGGAAATCTTCCGGATTTCAGCGACCGAGTGAGTACAGTAGCTATTAGGGCGAAGGAACAGAATGATCAACAAAGGAAGATGAGACGAGGCAACCCCACCGAGAGGGGGTAAAATCTCTTAACCCTTTTACCCCTTATCCCCAATTGAAATATCAGGAGAAGTTACGATGACCTATCGGATACTGAGCATCGATGGTGGCGGAATTCGTGGTGTATTAGCGGCGCGAATGTTGCAACGGATTGAAGAACGACTAGAGTTGCCGTTACGAGATCATTTTGATTTAATTGCGGGAACTTCCACGGGATCAATGGTGGGTGCGGCGATCGCGATGGGAATTCCCTGCGAGAAAATTGTCCAACTTTACCGGAAAAAGTCTAAAAAAGTCTTTCCCTACAGGAGCCGGTGGACCCTCAAGCGACTCCCGTTACTACTACAGCATGGTCCTTCTGCACCGAAGTTTTCCGAAGCAGGACTGATCCGGATGCTCAAAGATTTATTGGGCGAGAAGCGCTTGTCCGATATTAACCCAGCCAAGCTGTTAATTACCAGTTACGATACCATTGGCCGATCGCCCATTATTTTTAAAAGCTGGAAAGAGAAATTTGCTAATGTTCCGGTATGGGAAGCGTGCCTCTGTTCCGCTTCTGCTCCTACCTTCTTTCCGGCACACCGATTAGTCATTGATGGCGAGGTGATGTCGGCAATTGATGGCGGTTTAGCTGCAAATAATCCCACAGCTTGCGCGGTGGCAGAAGCGATTCGCCTGGGTCATCGTCTCGAAGATTTGGAAGTCATTTCCATTGGAACAGGTGCAGCAACGCGGGTCATTCCCTGGGAACAAGCGCGCTCTTGGGGGACGCTGCAATGGATTTGGGGAGGGCGCGTGGTTAAAGTGATGACCGATGCACCTTGCGAAGTTTATCACTATATCACGGATTATGTGATTGGAGATAAATCGCGCTATGCTCGTCTACAATTTCCCCTTGATCGCAGGTTAATTCATAAACCTTTGAGCGATGATATGGATGATGCCAGCAATGAGAATATCAACAATTTAGTTGAAGCGGCTGATGCCTATATGAATTTGGTTGAAGTTGTAGAATGCTTGGATATGTGTTTGAGGAAAGCTGAACCTCCTCAGGTTCATGTTCAAGAACGTTATCAACGGTAAGGGTTACTGTTAGATAGGTCTGAGGTTAGGGTTCGGATGAGCTATCACTAGCGCCGGACCCTTTTTGGTTTTCTGAATCTGGGCGATCGCCCGGGAATGCTCCCTTGCCGGGGAAAAATTAGCAATGAAAAAACTCCTGACCTTTTCAACAGGGGTCAAGGAGCGATGGAGCGGTACGAGTCTCGATGCTCGGACCCTTAGAGGAGGTTGAACTCAGCGATCGCCTAGATGGGGCGAATCTTGACTCATGCAGTCCCAAACCTCCATTCCAAGATTCAGCACTTGGCCCTTTAACCGAAGCGCCCGCTCACATACTCCAGGGTCGCTTCTTGTTTGGGATTTTGGAAAATATTTTCAGTTTTATCATACTCCACGAGATATCCAAAGCGCTTACCATCTTCCGTGGCTTGAGCATTGAAAAACGCGGTATAATCGCAAGACCGCGAGGCTTGCTGCATATTGTGGGTCACAATCACAATGGTGTAATTTTCTTTGAGTTCCTGCATCAACTCTTCGACTTTCATCGTTGAGATGGGGTCGAGGGAGGCGCAGGGTTCGTCCATCAGTACGATTTCTGGATTAATGGCGATCGCTCGGGCGATACAGAGCCGTTGCTGTTGACCACCGGATAAAGATAACCCATTGGACTTTAATTTATCTTTCACTTCATCCCATAAAGCAGCGCGACGCAATGAAGTTTCGACTAATTCATCCAGATTCCCTTTAAACCGATTGACTCGCGCTCCATAAGCGATATTGTCATAAATGGATTTGGGGAAAGGATTCGGTTTTTGGAAGACCATCCCAATGCGCCGACGGACCTCTACCGGGTCAATTTTTTTATCGTAGAGGTCTTGATTGTAGTAGGAACATTTTCCTTTAATGTGGAATCCACTAATCAAATCGTTGAGACGGTTAAAACATCGGATTAATGTACTTTTCCCGCATCCTGATGGTCCAATAAATCCGGTAATTTGTTTTTTAGGGATCTCCAGATTCACCCCTTTGAGGGCTAACGTATCTCCGTAATAAACGTTGAGATTTTCCGTTCGCAGAATTGCTTCTGTTTGGGGTTCTGTTTGATGATGATTGGCTGTTTGCCGATCGAAAGACATAAAAATCCACCTTGACTTTTACTAGATATTTCAACTTCAATGCAGTTGTGTTTCCCACTTTTATGCGATCGAGCGCCAACAGCCTAGGGTTGACAAACTACCGAACCCCAACCGCTCACATCCTCTAACCGGAGTTGCAGCAGATCGGAAGTGAAATTTTCAGAAGTCCGTGCGATCGCAACGGTCACAACTGCTCTGTTGATCGGTCTACACTGGAAAAAAATTAAACTTGAACAATCCTACTCTCAAGCAGAGCGCTGTATCTTATCATACAGTTTTCTGAAGTTTTAGATCGTTAAGAACTTTAATTTTTGCCCGTGGCATTGTGAACAGAAAGCATTATCTTTAATAAATGCTTTTCCGCGTGGCCCAGCGAGCCAAAATGCTGGTGAGTAGAACCAACAACACTAAAATCAATGAGGCAGCCCAAGCCAGTTCTTGTTGACTGGCGTAGGGAACCGAGGCAAAGTTATAAACCAACACCGCTAGAGAGGGGGCGGGTTCAAACAAGCCTTGGGGCCAAAAAAAGGTAAAGAGAGCCGTGAAAATTAAGGGAGCGGTTTCTCCAGCAGCGCGAGCGATCGCCAGGGTTAGTCCTGTGATAATAGCAGGTAACGCCGCTGGTAGCACCACCCGCAAGACGGTTTGATGGTTGGAGGCTCCCACTCCCACAGACGCCCATCGCACATCAGGAGGAACGATTTGCAGGGCTTCATCGGTGGTTCGGACGACAATCGGTAACATGAGGACCGAGAGTGCCACCCCACCGGCAAAAGCAGAGAACTGCTTGGTCGCTAATACAATGATACCGTAGGCAAAAATTCCGACAATAATCGAGGGAACCCCACTCAGCACGTTCGTAGCAAAGCGGATCCACCGGGCGACACGAACGGAACTGAACTCAGACAAGTAAACCGCGCCAAACACTCCAATCGGAACGCTAATCGCAGCAGCGATCCCCACCATAATCAGGGTTCCGGCGATCGCATTGGCAATCCCCCCTCCTTCCATCCCCGCTGCAGGTGGCAGTTCTGTAAACAAGTCCAAATTCAGCCGGTTAAACCCTTTAATGGTCACATAAATCATCACCGCGAATAACGGCACGAGGGTGAGCACTAAACAGGCACCGGATAAAACGGTCATCACCCAGACAAACAGCGATCGCGGAGTTTTATAGTTCCGCATTAGCTGCTCCCCATGTGGGTTCTCGTTGTAAAAATCGTCCCTGGGACTGGAAAAAGGCTGTGACATATCAGACTGGGTATTGCACCCCTAAACAACTGCGATGCTTTTGTGATTTGTCATTTGTCATTTGTCCTTTGTGGTTTTTCTTGATTATTCAGCCATCCTAATGACCAACAACCAATGACCAATGACCAACGACTAATGACCAATGACTAAAACTTCTTGACTTTCCGAACAATTAACTCGGCACAAATATTCACCACTAAGGTGAGCAGGAATAACACTAAACCCGCATACATCAAAGCAGAAATTTGCAAACCCGAGGCTTCTGCAAACTGATTCGCCAACAGGGAGGAAATCGTATTTGCCGGAGCCAGTAGGGAGAATTTCATGTCGTTAGAATTCCCAATAATCATGGTAACGGCCATCGTTTCTCCCATCGCACGGCCCAATCCCAACATGATCCCGCCCACAATTCCAGAAAATGCCGCTGGAATTAAAACTCGAATAATCGTTTCCCACCTTGTCGCCCCTAATCCTAGGGATGCCTGCCGCAACTCCGGTGGCAGGGATGCCAACGAGTCCCGAGAGATTGCCGTAATAATCGGCAAAATCATAATCGTTAAAATGATCCCGGCAGGTAACATCCCTGGTCCCACTGGACTGGTGGAAAAAATCGGCAAAAAGCCCAAGGTATTATGCAAAAACAGCCCAATCGGTTGCAAGAAGGGAATGAGGACAAAAATTCCCCATAATCCATACACCACACTCGGAATCGCGGCTAACAATTCCACCATAAACACCAGAACCGTCTGGACTGATTTGGGTAGAAAATCTTCACTCAAAAAGATAGCGGTCCCCACTCCCAGGGGAACTGCAAACAGTAAACCCAGGGCTGACGAGACCAGGGTCCCATAAATCATCGGCCAGACCCCATACTCATCCCGAACCGGATTCCAGGAGCTGGAGGTCACAAAATTGAAGCCAAAGGCTTGAATCGCCGGAATCGCCTCGATCGCCACCTGGATTGCTATCCAGACCAAAATCCCAGCGATCGCAAATGCAAAAATCCGCGTGATCCAGAAAAACCCGCTATCCATCACGCGCTCTTGTTGTTGGCGAGGTTGAATCGCTCTTTCCTCGTCCATATCCATAGTTTCAGCTAGTTTACTCATTACTTAAAATAAATTAAGCGATTTACGCTATCGCCTTCGATTATAGAAAAATAGCAGGCTAGAACGATAGCAAGCAGTCCAATCCGCTTGCTATCTCCTCAAATACCAAAACCGGACGGCTATTCGGTCACTTCAATGTCATATTCAGGGCTAATCACATTCGCTTTCTCGGCCACTTTCTGTCTGACATTCAGGGGGAGTGGAACGTAACCTAACTCGGGGGCCAGCAGTTGTCCTTCATTCAATCCGTACTCAATCACTGCTGAGAGCGCTTGAGCTTTTTGGGGATCGGAATACTCTTGGTAAGCCAGCAGCCAAGTATAACTAACAATAGGATAAGATTCAGCACCTTCGGGATCAGAAATAAATGCCCGTAGATTATCTGGCAGTTCTACTGCTGCTAGGGTTTTACTCGCGGCTTCATCGCTCGGAAGAACAAAGTTGCCGGATTTATTTTCTAAAGCTGCCATCGGGATATTGTTGTTTTTGGCGTAGCCATACTCAACATAGCCGATCGCACCCACAGTTTGTTGAATCCCAGCCGTAACGCCTTCGTTCCCTTTTCCGCCAATTCCCGTCGGCCATTCTACGGTTGTTCCTTCACCAATGCTCTCTTTCCACTTTTCACTAATCGCAGAGAGATGTTTGGTCAACACTCCGGTGGTTCCACTGCCATCGGAACGATAAACCACGGCGATCGCTTGATCCGGTAAGTTCACTCCGGGGTTCGCTGCGGCGATGCGTGGGTCATTCCATTGGGTAATTTCACCCATCAACATATCCACATAGACCTCCCGAGGAAGTCGCAGCCCGGTTTCCACTCCAGGCAAATTATAAGCCAAGACGATGCCACCTGCAGTCATCGGTAGCATGAGAATCTCCTGGTTCATCGCTTGGATTTCTTCATCCTTCATCGCTACGTCACTGGCCCCAAAATCTACAGTGCCTGACGAAAACTGCCGGATGCCAGCACCACTGCCAACGGATTGATAATTGGTGCGAACCTGGGGATTATCTTGATTAAATTCCTGAAACCAACGTTGGTAAATCGGCGCGGGGAAAGACGCTCCAGCACCTGTTAAGTTGACGGGTTCGGATAAGGCAAGTTTGCCGGTCCCTTCAGGGGCGACATTGCCTTCGGGAGCAGTGGTGTTATTTTCAGTAGGTCCCTGGCAAGCCCCGATCCCCAAGGTCAGTGCTACAACAGATAGGGAGAACACCATTCGAGCCGGTTTAATGGGATTGAGTAAACGCATCATGTGAATGGGTAGGTTTGGGTGTTTTTGTGACGATAACGATTGCAGAATACCGCTTTAGGGTAAAGATTGGGTTAATAAGCGTTAAAGTCTCTCTCTTAAAATTTGGCCCGGGTGCGTTGCAATTCTAGCTCATTCCTCTCCCCACAGGGCTTTTGCTCTGAAAAAAAGTAGCAAATTTGACAACAAATTTGGTCAATCCATGACTTAGGAGGTCATTGGTCATTGGTCCTTGGTCATTGGTCCTTTTCAGACTAAGGAAAAGCGATCGCCCGGTTGCTCTTACACCTGGGCGATCGCCTCTGTTTGTTTCTCAACTCTCCCTGGATCCTCGCCTTATGCCGGAACTTCGGTGGCGATCGCCTCGATCAACTTGCTCACCCGCGCTTTAATCTCATCTCGCACCGCCCGAAATGTCTCCAACGGTTTCCCATCAGGGTCTTCCAATTCCCAATCCTCAAACACCTCGCGCAATACCCACGCTTCGGGTAAATTCACCCCACAACCACACAGGGAAATCACCACATCATAATCCTCTGCCTGAAAATCACTCAACGGATCCGAGGTTTGATTGGTAATATCTACCCCAATTTCCTCCATCACTTCAACCGCAGTCGGATGGACTCGACTCGATTCTAACCCAGAACTGGTGACTTCAATTTTTCCCTCACCCAAGGTTTTAGCAAATCCTTCCGCCATTTGCGATCGGCAGGAATTACGCTTACAAACAAACATTACTTTCTTCGTCATGATTTTTCTCTTTTAACTTTGCCAAACCCTGCTCGAACTTATCTCAAACTCGGAAAACAACGGGGGTCTCGTAAGGTGGCTTTCTCCGGTTCTCGGGGAAACCAGTTCGCCGTTTTCTTACAAACCTCCACGAGCATTAACATCACCGGCACTTCGATTAACACCCCGACTACAGTTGCCAGTGCTGCACCAGAATTCAAGCCAAACAGCATCACCGCCGTGGCGATCGCAACTTCAAAATGATTACTCGCCCCAATTAAAGCTGCTGGCGCTGCATCTTCATAGGCGATATTCATTTTCAATCCTGCCACATAGGTAATCAAGAAAATAAAATTGGTCTGAATAAACAGCGGGACAGCAATCAATAGAATATGCAGCGGATTGTTAACAATTAAATCTCCCTTAAACGAAAACAGCAACACCAAGGTAATCAGCAATGCCGTAATCGAAATTGGCGTCAAATATTTCAAAAATTCCCGTTCAAACCACTGACGACCTTTATTTTTAAAGATCCAATATCGGCTGTACATCCCCGCTGCCAAAGGTAATCCCACATAAATCAGCACCGATAACACAATGGTTTGCCAGGGAACCGTTAAATCATTAGCCGCCAGCAACCATCTCCCCAGAGGCGCATACAAAAACAGCATGGCTAAGGAGTTAATCGCCACCATTACCAAAGTATGTCCCTGATTGCTAAAAGAGAGATATCCCCACATCAGCACCATCGCCGTACAGGGCGCAATTCCTAATAGGATGGTTCCGGCAATGTATGAGTTGGCGATAGAAATAGTCTCGTTGTTAATAATTTCCGTTCCCACAATCAAGGGACGAAATAACCAACCCAAGAAAAATTGAGCAAAAGCCACCATTGTGAAGGGTTTAATTAACCAATTCACAACTAAGGTTAGTAACACAGGTTTCGGTGCTCTAACTGCATTGGCTGCCTGGGTGAAATCGATTTTCACCATGATGGGGTACATCATGAAAAACAGGCAGATGGCGATCGGAATAGACACCTGATAGATGCTCATGGCATCTAGGGCAACCGCGACACCGGGAAACAATTTACCCAGGATAATCCCGGCAATAATGCACAGAAAAACCCACAGGGTCAGGTATCGCTCAAAAACACTCAGTTTGCCACCCGCTTGTACAGGCTGCCTCGAATGCTCGTTTGCCTCATTCACGACAATTTCCCTCGTCCTTACAGTCTCTAAATCGCTTTCGATTATACATCAAAAAAAGTTGATGAGTCAAGTTATTTCAATAAAACTTGATATGAGCAAGGAGAGATGGGTCAACCGACTGACCCTAAAACTTGGCTTGTTTGGTCAGCAATTCGCCAATGGTTAAATCAAAAGCAGCTTTGCCATCAAAGACAGTCCCCACCTTATGTCGGTGAAAATGAATGTAGGCCAAACGGTAGCCTTCTTCCGGTAGAGGGATGTAACCCACGTTGGAGACCAATTCCGGGGCTTTCTCTAGGTAAAATTCGACAAAAGCCTGAAGTGCAGGATTCTTCTGGGCGGCGTCGGCATTCACATAAATAAACAGGGGACGGGAAAGGGGCTGATATTGGGCGCTTTCTACGGTTTCCCGAGAGGGCATAATTGGACCTGTGCCATGATCCAGGGCGACTGCCTTGAGTCCTTCCCGATGTGATTCATAGTAGGCATAGCCGAAATAACCGAGGGCATTGGGGTCCCGACGCACGCCCTCAACTAGCGCATCATCATCCTCACTGGCGGTATAGTCATTCCGACTCGCATCGCTTTCCCCGACGATCGCCTCTGTAAAATAGTCAAAAGTCCCGGAGTCTCTGCCTGGACCGAATAGGGTCAAGGGGCGACTGGGCCAAGAGGACCGCACCTGATTCCAGTTGGAAATTCTACCTTCGGCCCCAGGTTCCCAAATTTTCTTTAATTCCTCCACGGTGAGGCGATCGACCCAGGTATTCTCCGGGTGAACCACCAAGGTAATGGCATCAAAGGCGATCGGTAATTCGATATAGGGAACGCCTGATTCTCGACAGGCGGCCATCTCTTCTAAGGTAATGGGTCGAGAAGCATTATTAATCGTCGTTTCCCCGGCACAGAATTTGCGAAACCCACCGCCGGTCCCGGAGAATTCCACGGTCACTTCTGCCGGATTGGGATGAGTTTCTCGATAGGAGTCGGCGATCGCCTGGGTAATGGGATACACCGTAGAAGACCCATCCATGATGATGGGTTGTAAGACTTGAGAATTGCTGTTTTGGCAGGATGCCATCAGGGCCGCTACTCCGGCGATCGCCGCCCACCGTTTCACGCCGCTCAAAAACTGCTGTGCTGTTGCGTTCATAACCCTTATCCCCAAAAAACATTTACGGGGTATAGGATAAATATATCAATAAAACTTGATTAGTTAGGTTAAATTTTAGTAAAGGCGAAATTCAGGAGTCTCCATTACAGGACCGAGCCGGGAGAATCGGACTAAACCTACGGTACTCAGCGAGGTACTGTTCGAGGACTGCAAACTGAGGGATATTCAGACTGTAATAGATCCAGCGCCCTTCTTGGCGAGCACGAACTAAAGCGGCTTCCTTGAGGGTTTTGAGGTGAAACGACAACTTAGACTGACTCACCTTGAGAATTTCGCACAGTTCACAGACACACAACTCGCGATCGCGCAGCAACTCCAAAATTGAAATCCGCAACGGGTCCGAAAAGGCATGAAAACCCGCTGCAATCTCTGCCGGTGCATTCTCAGTGGTATTAACCATCAACTTTTCCTGAAATATCTAGGCCCGATTTTAGCATGGGAGATGGGGCGGATGGGGGAGAGACGGAAGTCGTGACGTTGAACATCCTCCCTATCCTCCCCATCTTCCCTATCTTCCCCATCCTCCCTATCTTCACGCTTGCCTTTGTTTTGCCAAAAGCGCTTTAATGCGTTGCCAAATGGCTTCTAATTCTTCCACACTATATTCAGACAAAGGTCGATCGCAAGCAGCTTCCAGTTTAGAAAATCTCTGGACAAAGCGATGATTGGTCTCTGCTAACCCATCCGAAGGGTCTAAATCATACCATCGGGCCAGATTAATTACCACAAATAACAAATCGCCTAATTCTGCCTGTTGGCGCGCCTTATCTTCATGGGCGATCGCATAACGAAATTCCCCTAACTCTTCCTCAAATTTCTCCCAAACTCCCTCCACATTATCCCATTCAAAACCAACCGCAGCGGCTTTTTGAGAAATCTTCATTCCCGCCATCAAAGGAGGCAAAGTCCGGGCATATCGACCAAGTTTATCACTCAGTGGTTTGACTTCCGTTCCAGTTTCCCCTTTCTCTTCTGCCTTGATTTGTTCCCAATTCGTCCGGACTTCTTCAACGCTACTCACCTCGACATTGCCAAAAACATGGGGATGTCGGCGAATCAGTTTTTCCGCAATCCCTTCAGCAACTTCAGTCAAACTAAACTGGTTAACCTCACTAGCAATTTGGGATTGCAAGACGACTTGTAATAATAAATCGCCTAATTCTTCGGCAATGGCTTGTTGGTCCCCACTTTTAATGGCATCTACTACTTCGTAGGCTTCTTCGATAATATAGGGGATTAAACTTTCGGGGGTTTGGGCTAAATCCCAGGGACATCCCCCTTCAGGCGATCGCAACTGAGCTACCACCTGGATTAACTTTTCCAAGGCGGGTAAGGCGGAGGAATCAGAAGGGGTTGAGTTGGCAAAGTCTGAATTTGACATTTAGGGTGATACCTGGGTTACTAAAATAGACTTACATCACAAAAAATCAATAAAAATTAGCCAACTGGTACTTTTTCATCTTCGGACAAAAAGGCTAAAACAATTTGATTATTGGGAATACCTTTGTGTATTAATTCTTCGGTAATGCTGCGCTCCATTCCATCATATTCAATATAAACTTTTCCATCTTGTAACGTCACATAAATTAAATTTCCTCTCACTCGACGGCCTCTATCCCAACCGACTTGCATCAGCGCATAGCGGTCTCTAGTTTCATCGAAAACCGGATCTAATCGGATGTCTCCGTGAGAAGGCTTTAATTGAGCGTAACCCAGAATCACCTGTTTTACAATGTCTCGATAGGTCTGGCTGGTATCCATTGTTTTACCTCAGCTTCTTCCCAATTCACAATAATTAATTTTAGAGAAAGTTGGGAAATAACTAGCTCTCCAATTGGTTCCCTAAATATACCCAAATAAGTTATCTCAGGAATCGCTAAATAAATTATACGGTCTGGATCGACCTCCTGGAGTAATAACCGATAAAGAATATATTGCCCAATAGCTTGCTCTAAATCGGCAATCGCCGAGGGGTTGCGAAACGCTTTAATTTCGATAGCAATCCGCTGATTTTTCTGTTGAGCACCAATGAATTGTCCAGCCACTGCATCATTCATTGATGATTCCGTGGCAGCTAGATCGACAAACAAAAACCGTTCACCGTATGAAATGATATAAGGATCGTCGGTGATTTGCCAACCTTCTTTGATGAGGGCTTGTTTGACACTGTTATGGATAAAATCTCTTGTGGGCATCGTCTCCACTATATTTCAAACCGGGTTTAAACTTAAGATTTGCGCTTGGTGGAGGCTTTTTGAGGACGAGGGGTGCCGGAGGAGGTGTGACGCTTGATGCGTTTTTTTGCAGGAGTTCGGGGTTTTTTGCTTGGATTAAAAATAGCAGACCATCCGTATTTTTTGAATCGCTTGTAAGCAGATCCGATCCAATCACTGAGGGAATGACTCATGGCCCCCAGTTCTAATCCGAGGAAGAGGGCGATTCCTTCCATTGGGTGCTGTTTGACGGTGCGGGCGATCGCCGCTGATGCCAGGGGCGGATTCCAAGTAAACAGTCCCAGGTAATCCCCCACGAGGACGACTCCAAAGGCGATCGCCCCGATCCAAATCCCCAAATAGAGGATCCGCAATGCCGTCCCCACCAATGGCCCATGAGACAAAAAGGAGCGATGATGTAAACTCTGTTGATAAGGCAGCCAGATCCACCGCAACCACCCCCAGCGCTGAAACTGCTGAGAATAGATATCCAAATCCGGGCCAAACATCAGTCCACTAAACAAAAACCCACCGGCAACAATCAGCGTCAGACTGCTACTGCGGGTCTGTGCATAGGTTCCTCCTGCCACCAAGGGTAAGCTCCATAAAGTAATTTCGTCATGAGTTCGACCAGATGGCATGAAATTTCCAAAAACTGTGTTATGATGTGATCCGTCGGGAAAAAGGGCGTTTAGCTCAGTGGTAGAGCGCCTGCCTTACAAGCAGGATGTCACTGGTTCGAATCCAGTATCGCCCATTGTTAAATGTTATGGAATCTCATGCAAGCCTAGGGGCGATCGCTTGGTTCATGACTCAGGGTTATGATAAACTCGCGAAAAATGAGTTTTGGGTTGGTGCATGACCTATTGCCTCAGAATTGCCGATATCCCCACCAATGAGCGTCCCCGAGAACGATTGATGGCTTATGGACCGAAAAGTCTGGCCACTGCCGAACTAATTGCCATGCTGCTAGGTACGGGACAAGGACCGGGAAAATTGTCCGCAGTGGGACTTGGACAGTACATTTTACAGAAACTTGGCGAGAATCAGCGGGACCCCCTGGAAGTTTTGCGGGAGATGTCCCCCCAGGAACTGATGGAAATTCCCGGCGTGGGACCGGCAAAAGCCACCACAATTTTAGCGGCGATCGAACTGGGCAAGCGCACCTTTTATTCCAGGCCCCCAGAACGCAAAGAAATCGATAGTCCCGAAGCAGCAGCAGCGGCCCTCTCTCATGAATTGATGTGGCAAACCCAAGAACGATTTGCGTTATTGCTGCTGGATGTAAAAAATCGCCTAATCGGGACTAAACTGCTCACCATTGGTACAGCAACAGAAACCCTTGCTCATCCCCGAGAGATTTTTCGAGAAGTCTTGCGACATGGGGCCACCCGGGCGATTATTTCCCACAATCACCCCTCGGGGAGTTTAGAGCCCAGTCCGGAAGACATTCAACTCACCCGCCAGTTATTGCAAGCGGGACAATTGTTGCAAATTCCCCTCCTGGATCATCTGATTTTGGGGAATGGCGACTTCCAGAGTTTGCGGAAAATCTGTGGATTATGGCAGGAATATCCCCAAGGAGATTAGGGTTGGAGACGGGGGAAATTTTTTTTGCAAAGGGCTTGTGCATTTTGGGCAAGCTGTGCTATTGTAATAAATCGTGCGGGCGATTAGCACAGTGGTAGCGCACTTCCTTCACACGGAAGGGGTCACTGGTTCGAATCCAGTATCGCCCATTAATTTTTTAAAAACCTTTTTTCTCGGGGGCCAAGACTCAGCGGGATGTTTTGGTCTGGGTGAGCAATGGGTGATTGCCAATCCGATCCTCGTAGGCGGGGCAAAAACCGCTACCATAAGGGGTGCGGCTACCTGAAAAGCGATCGCTCTGCACGAGTTCCAGAAAGAAAAACAGCAAAACCCGGTTATAGCTGGCTATCCTGTGGATTGGGTATCAGCACGATTGAATGAGGTTTTTTTCAAAGAAATTATTAATACGTTCTCGGGTATTATCCTGATACAAATACCATGAAAATCACCCAAGTCCCAAGTCAATATTATCCAGTTTTAAACCAGTTAATAGAACTGGATGATACAATTATAGAGGATTTGGTGCAGTCCTTAAAGATTGTTCCACCGACCTTAGAGTTAGAAGCGTTAACGAAAACGGTGGCCAGTCAAGTTAGGACAATCAGTCAACACAGGATTTCCGACATCCTGGAATTTGTGATTTCTCTCTATGCCTTGTCCGATGAACATGAGATTACCCAGGATGAGGTTGTAAATTTTTTGGACAACTTTATTCGGAATTCTGAAGAATTTACTCATGTTAACTTAAATCATTTAGAAAGATTGAAGCATCGATTATCCAGATTAATGGAGCCCGGGGGTGTTCTTTATCTCTTATCTAAATCGGCTAATGTCATCCTGGATAATGAGAGAATATTGGTGCGTTCCGGACTCAATAAACCTGGCATTTGGGAAAAGAGCGGCAACTACAGAGTTCAAAATTTAGATCCAACTGTTTCTGAAGTAGAAAAGACCTTCCTAGAATTGGCCGAGCAATGGCGTAGAGAAACAAGAGGAATCTCTTCCACCAATAAAGCCTCTATGCATCCGCTCTATCAGCAGATTATTGGCATGGGGAAAGCGGTAATCCCCTTATTACTCCGAGAACTTGAACGAAACTCTGGACAATGGTTCTGGGCAATCAAAGCCATTAGTCAAGAAGATCCGGTTCCCCCAGAAAAACGAGGTCAGACTCAGGAGATGATCCGATATTGGCTGGAGTGGGGGAAGCAGAAAGGTTACAGATGGTAGAGAATGAACCGATTGGCAATTCAGCCTGGAGAACACAAGTTAGGGGGTGGATTGAAGCGGATTATCCCAATTTATTACGGACTGAATACAGACTAACCAGCCCAGATACCATTGATTACAATTGTATTGCTTGGGCGTTAGAAGATACCTCGAAATGGTGGTGGCCAGATGCAATGGAGCAACAGTATTGGCCGCCCCATGTTAAAAGAGAAGAAAGTTTAGAAGCATTTATTCAGGTTTTTGCATCTTTCGGATATGAAGTTTGTGAAATGGCTTCTTTAGAGGTGGGTTTTCAAAAAGTAGCCCTCTATGCCGACTCCAAAGGAATCCCTACTCATGCTGCCCGACAATTAGATGCGGGAAAATGGACCAGTAAACTTGGACAAGACGAAGACATAGAACATCACGAACTAGAGGGGTTGGTGGGAGAAAAATATGGTCAGGTTGCAGTTATCCTGAAACAATTTATCCCTTAAATCGTGGCGCTATATGAATCAGTTAATCGTTTGCAGTCTGTTGTTTATTCTCTGCTGCCGCCATTAATCAACGAGCAGATTAGCCCAGTTTTCTGCTGCAAGGTGGCGGTTTAAGTGAGGGGTGAAACCCTGCATTAAGGGGGACAAAGGATTAAGGCTTGATGATTTTCATTCCGGAGATAGAAATTTTCGGGAGACCGATCGCCACAGTTTAAGAGTGGGTAGACTACAATCAAACCATGACCAGCACCAATTTTTTTCCCGTATCCACTTAAACTTTACGATTAAGGTTGCTCGCTCATGTACGCTGCACCACAACTCCAAGACGATAGCGCGATCGCCTCCCCGCAGTTGCTTGACCCAACTTTGCTCAAAGCCGCAAGGTTGCTTTATCGAGCTTACAAGGATGTTCATCCCGATGGGATTCAACGTCCTCTCGGGGTCGCCATCGATCGCTTTACTTATCGAGGTCAGCTCATTTTTACCCAAAAGCCTGCTTTATTGCTGACGGAATGTTTTGTGCCGTTCGATCAGCTTGAAGCCGGACTCTATTAGGGGGAATGGGCTATGATGATCACCGGACAGGATAGGGTTCGGACTTTTTATTGAGTTTTGATGATTACCTATTGTTAATTAGGAATAATTGAATCAACTGTTTGAATAAAAAAACAACTCTTGCATTATTTTTTTAAAAAGTCTCACTGCTCAAGTCAACTGTTTAAAATCGGGTCATCATGGATGTGATTGTTGCGATCGCAGCGGTGGCAGTCGCCTTAACCTTGGGTGCTTCCATCGGCAGTTTTATCAACGTAGTGGCATACCGGATTCCTGCCGGTTTATCCTTGCTGTGGCCCCCTTCACGCTGTCCCCATTGCCTACATAAACTGGGTAAAACTGAGAACGTGCCAGTATTCGGGTGGTTGCGGTTGCGGGGTCGCTGTGCTCACTGCAAAAGTCCGATTTCCGTCCGGTATCCCATCATCGAAGCCTTAACCGCCGTCATCTTCATGGTGGTGGCATTGTTCACCTGGGAGAACCCGATGCAAATGATTGGGTATTGGGTCTTTTTTAGCTGGTTATTGGCCCTGTCGATTATTGATTTAGATACCATGACCCTGCCGAACCCGCTTACTCAGTCGGGATTGGTGGTGGGATTAGGGTTTCAGATGGTCACGGGGTGGGCGATCGCCTCCAATCTCCAAGGAATTCCCCATCAATTAATGGTCGGGGTAATTGGTGCAGTGCTCGGGATTTGGCTATTGGATAGCATTTCCTTTCTCGGTTCCATCGCCTTTGGAAAAACCGCAATGGGGGCCGGGGATGCCAAACTTGCGGCGATGATGGGGGCTTGGTTAGGTTGGAAATTGATGCTGCTAGGGGGTTTTATTGCTTGTGCTGCCGGTGCCTTTATCGGAGGGGGTGCAGTAGCCTTGGGGTGGCTGGAACGCAGTAAACCCATGCCGTTTGGACCCTTTCTCGCTCTCGGTGCAGCGATCGCGGCCTTGTGGGGAGACACCATTTTATCCGCCTATCTTGACCTCTTTTTTCCGTTGCAGTAAGAGGAGAAGTTGAGATTTCAAAACTTTCAACTCCCCTCAAACTGGGTTTTGATTTAATCTTGCCAGAGTTTAAAATCTCGCAAGCGGGACATTACTCCGCGAAGGTTGCTATAGTCTTGCTGAATCTTGCGGACTCGGGCTTGAAACTCCGGCAATTTGCCTTGATATTCGGCGATGTCCTGTAAATTGAGCAGATGCACAATGGCGCGATCGTAGGCTTTGACTTGCTTGCATCCAATCTCATGAAAGACCTGTTCCCAAAGGTAAGATTCCCGAGGCGCTAGTTCCTGAATCTTTTGAATTTTTTCCTGTTTAGCAGTCTGTTGTTCTTTCTGTTTCCGGAGTTTTTCTGATTGGACACAGAGGGTGAGCAGTTCAGACAGAGTGCGACCTGGAGAGTCGGACAAGGTTTGAGGAGTGGGCTTTTTGGAGAGCGATCGCAAACGCTGGCTGAGTTCCAGGTTGAGATTCAGTTCTCCTTGTAGCAAGCGCGCTAAAAATTTGTTTCGTTCCTCTTCAGAAAGCTGGGGAATTCTTTGCTGTAGTTCTTTAATAGAGTCCGATTTGGTTTCAGCTAGAGGACTCAATTGAGCCGCTGCATCAATTAAATCTTGATTGAGTTCAATAAAATCAACAAATGCTTGTAACGGTTTTGAAAGGTTGTGTAAATTGGCCGGAATAGGTGGTTCTATACAAGTGTCCGGTTCAAAGTCATAACAGAGTTGTGCAGCCTGTAACCAACCTAAGTACAAAACTCGGTAATCCCCTTGTAATAAATCATCGCGCAAGGATAACATCCTAGGGAGTAATCCTTCTCCTTCAGTCCAACCATTCAAATCTTCATCCAAAATTTTGATATCGATAATCACCGATTGTTCGGTTGTAGAAATTTCAATACCATCGGGGACTTGATAGGGTTCTAACTCAACGGGATTAATCAAAGATTTCGGCAAGCGGAACATCAGTTGGCGACTCCCCCAGTTCGCCGTATAAAGCATGATATCAAAACATTTTTCTAAAACCTGTTCCGGCTTGCCGCGAAAGTCACCATAATGGTAGAGAAATATGGCTTGAGTCCGATTGAGTTGAACACGACTGGATAGGGTACGGATATAGTCCTGTTCTTTCTCAGTTAAGGGACGGTCTAAGGCTTGGAACTCATAATATTGGTAGGTGCTCATGGTTGAAAGGGGGTAGAGGTTCGGAATTTAGGATATGAATTATAATACCGGAAGGGTTTACGGTTGAAAACCTGGTGGGGATAATCCTAATCCGCAATGATTTAAACGGGAGAATAAAGCACATAATCTCCAGTAACTTCGGACCCCATAGGTTTGACCGATAGTGTAATGCCATATTGGAGCGCAAGGAAGGTGACCTTTGACAGCATTTAAGTTAAACTCTCAGGGCTATTTCATTCTAAACAACTCCTTAATTAGTTTAAGGCCAAATCCCGCCAGACGTTGGGCTTGAGCCATATTATCGAATCCATAATCGCGGTATATATTCAGTGCAAAATTTCGAGCGGCTGCTCAAATTTGAACTAAAGGTTTTGTCCTTATACGAGAAGCATCTTCACCTTGAGTTACATCCCGCACCAGAAGTGTTGAATGTCAATAAAAACCTGATAAGAATAGACCGAATCATGTTATAATAGAGGCTAAAAATTTAAACGTTTGAGTTTAAGCATGACTAAAAATTCATTCTCCCAGATTGTCAAAGACATTTTGAAATACCTGCCCAAAAATGATTATCCGGTATTGAACAGCCGTCTGTTTGTCGATTGCTGGCTATCTTATGTAATGGATAACAGCTTAACCAGTATGCGAGATTTATTTATGCATATTAAACAACACTGGGTTTGACGTAGATATTTCCACCTTTTCCAAAGCGAGTTCTCACCGCGACCTCAAACCTTTTCAAAAAATTTATCAAAAATTGAATCAATTGGTACGAAGGGAAAACATAAAAAATTACACGATAAATACTCAGTTTGTCCAATAGATTCAACAATCATAACTCTCACCAGCAAATTGTTGTGGGTTCTGGAATATCATCAAGTGAAACTTTTCAGTTTTCTCAATCTAGCTACGGGAAGCCCCGAAGATAATTTCATCAATTTTGGATACGATCATGATTACAAGTTTGGGTCTAAAATGATGTCTAGCTTACCCCAAGATGCTGTCGGGGTAATGGATAGGGGATTTGCTGGATTAAATTTTATGTGTGAATTAGTCCAGGAAAATAAATATTTTGTTCTGCGGATAAAAAACAATTGGAAGTTAGAATTCGAGGAGTCATCGGGGGTTAGTTAAAGTGGGGTCATCTCGTGATGCTAACGCTTATCGAGTCATTAATTTTTGTGATATAGAAACCAAAACTGAGTTCCGCTTAATCACCAATTTACCTAATGAGGGAGACGCCGCAGTTTCTGACGATGAAATTAGGGATATTTATCGATTGCGTTGGGCAGTTGAATTGTTATGGAAATTTTTAAAAAAGCATTTAAAACTTGAAAAATTAATTACCAAAAACGTCAATTGTATGACCATACCAATTTATGTAAATTTAATAGCTTATCTGATTTTACAGCTTGTATCCATTCCCGAACAATGGGGACATACGCTATTAGATAAATTTCGCTATTTACAATCTTGTATGTGTCAAAAAATTAGTTATGTTCATTGGTTTGAGGAGATAATGTTTTGTTGAGTAATTTAGCCTTTGAAGGCTTAGTGTAACTTGCAATGTAAAGTTTTGTATCGACATTCAAGATTTCTGGATATTTTCCCTCTTTCTTCTGAGGTAGATTTCTTATTTTCCTCCGCCTAAAGTGACAGGAAAGGGATAGAGAAAAATCGGGTTTGCAATTGGCGTTGGAACGTAACTCTTTCGCGAAGATGGGTAGGGGCAAACCACTCTGGCAAATGGTTTGTAAGATTTGGCGTTCTAACTCAGAATTGGGGTCGGTTTGTTGTAAAAATTGCCGATAGTGCAACTCTTGATCGCCTCCCTCTTCAACCCCTCAATATCCCGACAGGGTGTCTATGGCTTATTTTCGCTTGCTTTACAAAAACTTTACGGAATTCGCCTTTTTTGTAAAGTGTCTGTAAAGTTAAGGGGAATTGTATCAAAGAAGAAAATATTATCAGGCATTTTTATGCTTTTATAGAAAAATTAGAAATAATCATAAGCAAAACTACTTAGCAGCCATTGCCCGATAGGTGCTTTTGATGAGACTGTGGCGACTAAGGGGCGCAGGGATAATGGAGAGGTAGAGCAATTAAAAACGAGAACTGTTGGTGGGAAAGGTACGCGCACAGGCGGAAGGGGCTTTCGTCGCTTTGACAGTTTGCGGCTGACATAAAGTTTTGTAACAATTTCCAGCATTTCCCGTAAAACTCAGAACCTTCCTCAGAGAGCAAGATAGAGGCAACTGTCAAAGTCCGTCTGAATCTGTAGTGCCTCTTAGCTCGAAAATAGAGCGTGAATCTATAGACGGAGTTCTCTTGGTGACTTGGACCCAGAATCAGAGGTGCTTAAATGCCTGGAATCAACGACAATGAGTTCAATCTTGTGGGGGGTCTGACTGATGACTTCCTTGAAGATAAACTCGTCTCTCCACTCCCATCAATTCTTGCGGCTGGCAGCGAACTCTCGCTGGATGCCGATCGCCTGGGAGAGGCGTTGACTCCAGAACCTTTTGTAGAGGGTGAAGATGAGTTTCCCCAGATGGTTTTGGAAAAGGGTAACCTTTTAGATAAGGAAGTTATAGTTTCCTCCACGCCGGACAATTCCGACAGCGATTCACTGACGAATTATCGCCAAGACGATGAAGTTACGAGTTTAATCGATATCGATGAAGACGATCCCCTCATCAATGGTGGCGATGTTTCATCTGAGGGATCCCTAAGCGAAGAACCATCAGAGAGTGACACCGAGGAAAGTGATAGATTGTCAGACAATCCTTCTGAAAGTTCAGAATCGGACAATAGCGATCGCAAGACCCTGGCAGAGGATCGGGATGAATTCTTAGAAGCAGAACCCCCCACACTTGAGACGGATGACGAGGCGATCGCACTCGATAACGGTGGCGCTGTTTCCGAAGAGGAATCCCATAGTGAAGAACCATCAAATAGTAACACTGAGGAAATTGAGGGATTGGACAATCCTTCTGAAAGTTCAGAATCAGATAAGAGCGATCGCAAGACCCTGGCAGAGGATCGGGATGAATCTTCAGAAGCAGAACCCCTCGAACTTGAGACGAATGACGAGGCGATCGCACTCGATAACTCACCTCACCTTATCAGTGACGAAGAAACCCCCGCATCTGACACAAATTCTCTCAAATCATCTCTTTCTGACGTTCCGAATGAGGACTCTGGCGAATCGGCATTATCTTCAGCAGTCACCGCTAGTTCAGGGGAAACCGATATTGATGTCGAGGTAGAAGATACTAAAGAAAACACAGAGGCAGACATCAAAGAAAACCCAGAGAGCAAATCCCTACTTAATTCCGACCGAGAAACTGACAGTGACTCGGAAAACAACAATGAAACTAGCATAACCGATGCCACAGCTTCATCGGATGGAGATGATTCCAACCTTCCAAAAAATCTGGAGAATTTTGCCAATGTTACCTTTGATTCTGGTGTTTTCGTCGTAGGGGAAAGTGGAAAAGTTCAGTTTGACTACCTATTTGATGGCGGAGGCTATGAAGGAAAATTGGCAGCTTTTAGCTTGACTGGAATGGAACCCTTTCAGCAGCAGGGTCTAGAAGCATTTATTCAAGAAGCATTGCGGCGCAGCTTGAGTCAATCTCTAGAAGGTCATGTCGTGATTTCCGATCGCACTGAAGGAGCGAGATTTAGTGGCGAACTCGGAGAAGCTAATCAAAATCGTGGCGACTATCAGGGAATCAAAACTCTGGACATGACGCCAGGGGATAAATTTGGAGTTCTGCTGGTGCCGCAGGGAACGCTACAAGAGGTTTGGGAACAACTAGAAGCAGGCAATTTTGAGTCGGTTTCGGCGGCAAAACGTCCTCTGTTTTCGATGTCTACTGCTAATCCAGAGGATGGATTTAACTTCGGTCAAATAGCTGATGTGTTTGGCGACGGCAGCACTTTTGTGTTTGAAGATCTGCGAGTAGATAAAGGAACCGATCTCGATTATAACGATGTAATTTTTCAAGTCCGAGGTGCGATCGCAGAAGCAGCATTCCTCAAAGATGTCATCAATCCGAATAAGAATTGGCTGGAGACTGGTGAACTAAGCAAAGCGATCGAGAATTACGCCAAACGAGAAGTAGATGATAGCACCGAAGAGGAGACGGAACCACAAACCCCGATCGCTGAAACGTTACCGGATTCGGTGAAATATGCGCTTTTGCGATCGCAAGATTTGGAGAACTATGATCCGAAAGCATTAGAAACAACCCGTCAATGGGTTGTAGGAGTCACACCGGGTTATTCTGCTTCAGAATTTGCCACCCTTTATAATGCTGAAGATATCGGTGCCACCGGACATATTCCCGACACTTACATCTGGAATTTTTCCGAATTTGGCAACGCACAACAAGTCGCCAAACGATTGAGCGATCTCAAGGGAGTGGAATTTGCCTATCCCTTGACGCGAGTACAACTCGAACCCTTATCGACTCCTAACGATCCATTATTTAACCAACAGTGGCACTTGGAAAATACAGGTCAAACGGGAGGAACGGCGGGAGTTGATGCCAATATAATAACCGTGTGGGATGAGATAACTGGGGAAGGCATCAAGATTGCCATTGTGGATGATGGAGTGCAACACACTCACCCCGATTTAAGCGATCGCTACCGTCCCGATTTGAGTCTTGATCTCAATGAAGGAGATATCTTACACCGCAACTATGATACCGATCCGGCACCCTTTTCCCACCAAACCATCGCCTCCAATTTTGCCAATCCTCAACCGCTAATTGATAATGATTGGAGTTGGGAACTCCCGACCCTGGACGTTGGGTTAAAAGGAGTAATCGATCATGCTAAACTCAAATTTAATTTCGACCACCCTGCTCCCAACGAGTTAGATATTTATCTTTACAGTCCGAAAGGAACCGACCTGCTACTGCCACCAATAACCACCAGTGGTGAATTTGAAATCGACACGGCATTATTTAACGGAGAAGAAGCAAATGGCGAGTGGAGGTTAATGTTTGAAGACCGGGTTTTAGGAAACAGCGGCACGCTTAATAATTGGTCTTTAGAGTTGCAAGCCTCTAATAAACACGGCACCTCAGTCGCCGGAGTTGCTGTAGGAACCAGTAATAATAATTTAGGAATTAGTGGGATTGCGCCAAACGCAGAGTGGGGAGGAATTCGTCTGATTGCGGATAAAGTAACCGACATTCAAATTGCCGATGCACTTTACTCGAATTTAAACCAATCAATCCAGGTTTATAATAATAGCTGGAAACCCCCCGCCTTTTGGTTTGGCGAGCAAGGTCAAGGATTGATGGCGCTGCATCAAGGCGTAACCACAGGTCGAGGGGATTTGGGGAATATTTACCTGTTTGGTGCAGGAAATGATGGGGAAAATGTTGAGAATATCAATTATAATGCTTATGCAAATTCTCGTTACACGATCGCAGTAGGCGCGGTGGATTCCCGAGGTCGAAAACCCTTGTATTCTCAAGAAGGCGCGGCCTTATTTGTTTCTGCACCTTCCAGTGGCAATACTGGAGGAATTACCACAACCGATTTGCTTGGCGATCACGGTTGGAATAGTGAGGGCAGTGGCAAATTTGGCTTAAATTACACCGATTTAGATTACACCAATGACTTTGGCGGCACCTCTTCAGCGACGCCGGTGGTTTCCGGTGTAGTGGCGCTGATGTTGGAGGCGAATCCGAATCTGACTTGGCGCGACGTGCAGCATATTTTAGCAGAAACTGCGAATCGAAATGCGATCGCAGATTCAAGTGCAAATTGGAGTGGCAATGATGGCGATCGCATTCGACACAGCGATCGCTATGGATTCGGATTGGTGGATGCGGCAAGTGCCGTTGCTGCTGCCTCGACTTGGACATCAGTCGCGCCAGAAGTTGCCATCACTTCGGGCACTTTAACCGTCGATCGCGCCATTCCCGACAATACTTTTGCTGGAATCACTCAAGAATTTACTCTCGATCGCAATATCACCCTTGAATCGGTGGAAGTGGTGTTTGATGCCGATCATCCCTATCGTGGCGATTTATGGATAGAATTAACCGCGCCAGATGGTACAAAGTCTCTCTTGGCAAATCCTAGCAATGATGATGGGCATGATTATCAAAATTGGGTGTTTAATTCCGTGCGTCATTGGGGTGATTCTTCCCAAGGAACTTGGCAATTGCGGGTGCGAGATCGGTATCCTTCCTATTCCGGGAGTTGGAATTCTTGGAAACTGAATTTTTACGGCACCCAACCTACTGTGACGTTGGAAGCGAGTGATACTAATGCATCGGAAACCGGGGATGCGGGTGAATACACTTTTATTCGCACTGGCGATATCACTCATCCCCTGACGGTGAGTTATGCGATCGCCGGTTCGGCAACCAATACTATCGATTACACTGAACTCACCGGCAGCATTACCATTCCCGCAGGTAGCGATCGCATCACGCTTCCCCTGTCTGCGATCGATGATGAGGAAGTAGAAGGCACTGAGACGGTGGTGCTAACTTTGGCGGCAGGGAGTGCTTATAATGTAGGAACTCAAAACATGGGTACGGTGGAGATCGCCGATAACGATTTACCGAATGTGCCTCCCACCCTAACCCCGCAAACGGCTACGCAAACTTACACCGAAGATATTCCACTGGATCTTATCGATTTGGTCGTCAGTGACCCCGATGCTGGGGATACCCTTACTGTAGAATTGCAACTCGACCCCACAGCCGGAATCTTGACAACCGGCACGGTTGATGGTATCAGTTCAGTCTATAATTCGGCAACGGGACTGTGGCAAGTAAGCGGTGATGTCACTACCGTCAATGCTGTATTAGCGGATGTGCGGTTTATTCCGACAGAAAATTATTACGGTGAGGTGACGATCGCCACTTCGGTGACGGATAATATTGCGCCTGCGGTGACGGGTGCGATCGCGCTGTCTGGTACGCCAGTTAATGATGCTCCTGCACTTAGTCAGATTACCACCCTCTCCGGTGCGACGCAAGGTTTGCCGTTTACTATCAGTTATGAAGATTTGCTGAATGCGTCGGATGCGTCGGATGTTGAAGGCGATGCGATCACGTTTCAGATTGCGGGAATCACCTCCGGTACTTTCACGAAAAACGGTCAATCGGTGACGGTGGGGGAGACTGAATTGGCAGCGGGTGAGTCGCTGATTTGGTATCCCGACACGATGGGGAATGCAGTGCCTGCGTTTGCAGTGACAGCGTTTGACGGGGTAGATGAGTCTCAGAATGCCGTGAATGTCGCGATTGCAGTGGATGAATTACCGACGATAATCATTAATGCCACCGATGCGATTGCTTCTGAAAGTGGCGATCGGGGTCAATTTACGATACTGCGTAGCGGCAATACCGATAATCAGCTAACGGTGAATTTAGCGGCAAGCGGTAATGCAGTGAATGGCAGCGATTATAGCGCAATTCCCAATAGCATTACCATTCCTGCGGGTCAATCTTCGATTGCGATCGATATTACGGCGATCGATGATAGCTTAGTCGAAGGGGATGAACAAGTCATATTGACGTTGAGTGTAGGCAGCGACTATCAAATCGGCGGTCAAAATAGCGCCACTGTCACAATTGTCGATAATGATAACGAACCCCTGCCAATGGTGATGCTGGCACCGGGTAATTTGAATGCTTCGGAATCCGGTGTAGCGGGGAATTTACTCGTATTTAGAAATAATGGTTTAGGACAGGAATTAACGGTAAATTATTCTTTGGGTGGCACGGCAGAAAACGGGGTAGACTATCAACCGCTTACCGGCAGCGTCACGATTGATGCGAACTCTTTCTTTGCCACAATTCAGATTATTCCCATTGACGATAGTGAATTTGAAGGTACCGAAACCGTAAGCGTGAATTTAGTGGCAGGTGCGGGTTATCAGGTCTCGCCAAATGGGTATGAAGTGCAAATTGCCGATAACGATAAACCCAGTGTTAGCTTGGTGGCAACAGATGGAGAGGCGTCAGAAGATGGGGATTTGGGTTACATGACCCTGACGCGCACTGGAATTACTACTAATCCCCTAACCGTGAATTATGCGATCGGGGGTACGGCGACAAATGGCATGGATTACACTGCCCTCAGTGGCAGCATTGAAATTCCGGCGGGTTTAAGCAGCATTACAATTCCCATTCAGGCGATCGATGACAATAGTGTTGAAGGAGATGAGACTGTTGTGCTGACTTTGACGGACAATAGTGCTTATAACGTGGGAACCGATAAGACTGCCACAGTAAGTATTATTGAGAATGACCTCGAACCTTTTACTCCAGTAGAGTCCATTCTAACAGGTGTCGATAATGGTTCTGTAGCTTGGGGAGATTATGATGGCGATGGCGATCTCGATCTGCTGATAACAGGTCGGCGAGGAATGTCTCGATTTTCTAAAATATACCAAAACAACGGAAGTGGTAATTTTATAGATATTGATGCTGGATTAATAGGAGTCGATAATGGTTCTGTAGCTTGGGGAGATTATGATGGCGATGGCGATCTGGATATTCTGTTAACAGGCGATTCCAATGGTAACAGCAATGGAATTGCAAAAATATACCGAAATGATGGGGGAAATTTTATTGATATTGCAGCTAATTTACCAGGTGTTGTGAATAGTTCGGTAGAGTGGGGTGACTATGATAACGATGGAGATCTGGATATTCTGTTAACGGGTCATCACTTTAGCAGTGGGGGTTATGGGAGTGGGGGTTATGGTGGAGTTGATGTGGGTACAATATCTCAAATTTATCGAAATGATGACGGTACATTTATCGAAAGTGGTATTTCTTTGATAGGTGTAGGCAGTGGTTCCGCAGCTTGGGGAGACTACGATCGAGACGGGGATTTAGATATTGTCCTAACGGGGATTACAGATGATGGTTCATCAATCGTTGGAGTGTCGAAAATTTATCGCAATGATAGTGGTAGCTTCACCGATATCGGTGCTATGTTGCCGGAAATTTCATGGAGTTCAGCCGCTTGGGGTGATTACGATAATGACGGCGATCTCGATTTGGTGATAACAGGGTTTAATGATACAGTTGGTGAAGTCTCTCAGCTTTACCAAAATAATGAAGGTACATTTATTCAGGTAGAAACAAACTTACCTGGAATTACTGATAGTGCCGTTGCTTGGGGTGATTATGACAATGATGGAGATCTCGATATTCTATTAGTCGGCCAAAAGGAATCTTCTAACTCTGTTGCTACCATTTATCGAAACGATGGAGATAATGAGTTTACTGACATTGATGCTAATTTGAAACTTATGCCTCCCAATGTCTATAACACCGGAGATCGCTTTGCAGTCTGGGGAGATTATGATAGAGATGGAAATCTCGATATTCTTCAAACGGGTCTAGATAGTTCAAATAACTTTATCGCTCAAATTTACCGAAACAATAGTGTAATAGCTAATAATTCCCCAACCTCACCTGATGGACTTAATGCTTTAGTTCACGAAAATTCCGTCACTTTAAGTTGGGAGCCAGGCACCGATTCGGAAACCCCACAAAATGGTTTAACTTATAACCTGCGAGTGGGAACGACTCCCGGTGCTTCCGATATTGTATCACCAATGTCTAATAGCGATGGCACTCGGCAACTGGCTCAAATGGGGAATGTTCATCAAAACACCAATTGGACGATTAACAACCTCAAACCAGGCACTTATTATTGGAGTGTCCAAGCAGTTGACAGTGCTTTTGCCGGTTCGGAATTTGCCACTGAAGGTACTTTTACGATGACTGCAATTGGTGAAATTCAGTGGATTCAGCAAATTGGAACAGCTAGTTTTGATGACTCACGCGAAGTCGCAGCGGATAAGTGGGGGAATGTCTATATTACCGGATATACTTTAGGTTCTTTAGGCGGGACTAATGCCGGAAATCACGATGCAATCTTGACGAAATATGACACGAATGGCAATTTACTTTGGACGCGACAACTCGGTACTCCCGAGGTTGATGTAGCATTTGGTGTGGCTACAGATAGTGTGGGAAATGTCTATATCACTGGACAAACGGCTGGAGCTTTAGAAGGCACCAATGCAGGAAATGATGATGCTTTTGTGACGAAATATGACACGAATGGCGATTTACTTTGGACGCGACAGTTAGGGACCCCGGGTGTTGATATCGCCTATGGGGTGGCGACAGACCACGATGACAATTTCTATATTACAGGTTACACCACAGGCTCGTTGGCGTCACCCAATGCTGGAGAATATGATGCCTTTATTGCCAAATATGACAGCAATGGCAATCAACTTTGGAGTCAACAGCTTGGCAGTTTGCAAACGGACATCGCTCGTGGAGTTGCTATAGATGGAGGAGGTAACGTTTATATTTCTGGACGTACTACTGGTTCTCTAGATGGCAATAATGCAGGCAATTTTGATGCCTTTTTTGCCAAGTACGATCGCGATGGCAATCTGGTTTGGATTCGACAACTTGGGACTTCTGGATGGGACCAATCTCCAGGAATTAGCACAGACAAAAATGGCAATATTTACATTACAGGATACACAACTGGAAATTTAGAGGGGGTAAATGCTGGCACCCGAGATATTTTTGTGACCAAATACGATCCGAGTGGCAACCTACTGTGGACAGAACAGTTAGGGACTTCTTCTTTGGATTATTCCTATGGATCTGCTACAGACAGTGCTGGAAATGTCTACATTACTGGACATACAACAGGTTCTTTAGAAGGCGAGAACTCTGGAGGGTATGATGTCTTTGCGATCAAATTGGATAGCAATGGCAATCAAGTCTGGATTCAACAGTTTGGCACTTCAGCAATTGACTATTCTCGTGGTATTGCTACAGATCCGGCTGGCAATATCTATATTACAGGAAGCACTCAAGGCTCTTTCGGTCAGACTACCGCTGGAAACTCTGATGTTTGGGTGGCTAAGTTGAGCTAAAGGGGAGGGGAATGCGCCAAGAAGTCAGCGCAGTGCGATCGCCATTCGCCATCGCTCGTTTAATCTGACAAGCGTAAACTTTTATGACAATTTTCGCCATTGGCCGTAAAACTGCCTAGGTAGAGCAGAGAGAAAAACAGAAAGACCACGCTAAACTCAAAGGAGCAACTAAACCATGACTTATTTTTGGAATCTGGAAAACCGCGAACCGCAAGACCTTTACGGTCATCAAATCGAAAGTCTCAGCGGGGGTTTCCTCTCCATTAAATCGACGACGAATAGCAATGCTGAGGCGATTTCCCTTCCTTTCATCTGGGGACGAGGTGGCAGTTTTACTCGTAGTCACCGATGGATCGACCCGGATGAAAATTTTACCAATACGTTCGGTCAACGACCGGATGATGTTTACTGGTGGCAACTTCGTTCTCTCGCTTCTAGCAGCAATAATACCAATGGCGGCATTAATTTAACCTCGGTGAACCATCAGGAAGTCTCTTCGGAGGATAACATTTTCTTAGTTTTGGCGCAAAATGATATTTTAGATCCGTTTATCAATACCGCTAATCCCATTCGATTTAGAAGTGAAAATCCGCTAACCGATGAAACCATTTTCAACCGTTTGTTTACGCAAGACTATCAAGTGGTTGAGGTGACGGAAATTTCATTTGAAGAAACCGAGACAAATTCTCCTGTGACTTCAGTTCCCGAACCTTCATCTTATGTGGGGGTGCTGGTGTTGGGAATCCTGGGAGTCGGTTTAGCTCTCAAACGCCAACTGGGTACTATGCGATCGCGCTCATCATCCGTGTAAATCCCTGAAATCTATGCTTCTTTCCCCGCCACAGACTCCATAAATTTGTTAAAATTTTCGCCATTGGCCTTAAAAATGCTTTGCAAAGGTATACAGAAAAATAGACAGGCTAGGCTAAACTTAAAGGAGTAACTGAACCCTGACTTATTTTTGGAATTTGGAACACCGCGAACTGCAAGACATTTCCGGTCATCAAGCAGAGGCGATTCCCATCTTTTTCGTCTGGGGACGAAGTGCCAGTTTTACTCGCAGTCGGTGGTGGATCAAAGCGGATGAACCCGTTTTCAATCGTTTGTTTGAGCCAGAGGAGCGAATGATTGAAGTGAAGGCAATTTCATTTGAGGCAACCGAAACAAATTCCTCCGTGACTTCAGTTCCACAACCTTCGTCTCATTATGTGGGGGTGCTGGTGTTGGGAATCCTGGGAATCGGTTTAGCTCTCAAACGCCAACGGGGTACTATGTGATCTCGCTCATCCCTACTCATCCGTGAAAATCCGTGAAATCTGTAGTTCTTCCAGTTTGATTTTTCCCGCTTTCGGTCTATAATTCGTTTCCGGGCGGGAAAAAACACAAGGAGCAATAATTATGGGTCATAGGCAGCGATCGCAGATATCTGGATCCTCCCTTACCGGGAAATTGGCGATTTTGTCGATCGCGCTTTGCTTGTTCCCCCCGATTGCCGTCGCACAAATTGTCCCGGATGCCACCTTACCTGTTAACTCCATTGTCACCCCGGATGGCGATGCTTTAATTATCGAAGGGGGCACCTCATCTGGCTTTAATTTATTCCACAGTTTCCAAGAATTTTCCATCCCAACTGATACTGCTGCTTTTTTTAACAACGATCCGACGATTGCAAATATTTTTACTCGAATCACCGGGATTTCGGTTTCTAATATTGATGGGGTTCTCGCAACCACTGGAACCGCCAATCTATTCTTATTAAATCCGAACGGGATCGTTTTTGGTCCTAACGCTCAACTCAGTATCGGCGGGTCGTTTTTGGCAACCACCGCCGATCGCTTCACGTTTGCCGATCGCACCCAGTTTGGCGCTGACGTCCAAACCCCACCTCAACTGACGATTAGCACTCCCATCGGATTGCAATATGGCAGCAATCCTGGGGATATTGCAGTGGGAGGCGCTGAATTGCAAATCAGTCCCGGCGAAACCTTAACTCTGGCAGGGGGAAATGTTTTTTTAGAAGGCGCGGCATTATTGGCAGAGTCGGGACGCATCGAACTCAGTTCGGCGATCGCCGGTGAGTTGTCTCTGATTCCCCTCCAACAACCATCAGAAACAGCATCAACAGTCACTTATGGAGATATCCAACTATCCCAAGGCAGTGCGATCGATACCAGTGGAGAGGCAGGTGGCGATATCCAGTTACAGGGTCGGCGGATCGAACTGCGCGACGGTTCCCTACTGCAAACCACTACCTTGGGCGAAGCGCCTGGAGGCAACCTCACCATTCGCGCCGCCGAATCTCTGAAACTGAGTGGCAACGATTTAGCGGGATTTCCCAGTGGGTTACTGGCAGAAACCGCAGGTGCAGGGGATGGCGGTAATATCGGCATCGTGGCGCGGCGGGTTGTGTTCCAAGATGGGGGACAGGCATCGGCATCGGCGCTGGCAGGGAGTACCGGCAATGGTGGGAATGTGAGGGTGAATGCCTTAGAGTTTATCGAAATCAGCGGATCCACAGGCGCGATCGCTGACCCGATGACAGGGGAGGAATTTGGTCTGAAGAGCGGGCTTTTTACTGAAGCTCAAGGTGCCGGAAATGGTGGCAATATCGAGATAAACAGTCCTCGCATCACCTTGCGAGATGGCGCTCAAGTCAGTGCTGTCACGATTGGCGCAGGAAACGGGGGAAACATTGCGATCGCCGCCACAACCGTAGAACTGGTCGGAATTTCTGGGATATTGGTCAACGCAGATATTGGATCGAGTGGCGATGGCGGAGATATTGCCATCGCTACCAATCAGGCGATCGTTCGCGATGGCGCACAGATTGCTTCTACCACCTTCGGTGAGGGAGACGCTGGAGATATCCGCTTGAATGCTTCGGAGTTGTTGCAAGTGAGTGGAACAACGGCAGATTTTTTTGGCGGAATTTTTGCTGAGGTAGCACAGGAATCCACTGGCAATGGTGGAAATATCACCCTAGAGAGCGATCGCCTGTTAGTGGATAATGGTGCCAGCATCTCCACCAGTACCACAGGTCAAGGTCAGGGAGGCATTTTAACGATATACTCGCAATCCTTGACGGTTCGCGGCGGACAAATCGCGGCGGCGACGGTTGGCGAGTTTCCCGGTGGCAGCATTTCCATCGTGTCCGACTCCGTAGAACTCAGTGGGACCACTCCGGATGGATTTCCCAGCGGTATATTCACTCAAACTCTAGGGTCTGGAAATGCGGGAGATTTAACAATATCCAGCAGTCAACTCACGATCCGAGATGGCGCAAAACTTTCGGTGAGTGGCGAAGCGACGGGGAATGCAGGTAGTCTCACGGTGAATAGCGACGCCCTTGAATTGCAAAATGCTGCAATTCTCACGGGCGAAACTGTTTCCGGACAAGGTGGCAATATAGGCATCAATGCCGACACGATTATCTTACGCGGAAATAGCAATATTTCCACCACCGCAGGCACTCAGGATAATCCTGGCAATGGCGGCAATATTACCATCGATACCGAAGCGATCGCTGGGTTGGAAAATAGCAATATTTCTGCCAACGCTTTCAACGGTTCTGGGGGTGCGATCGCGATCGCGACGGATGTCATCCTGGGACTGGAGGCGAAGACGCGGGAACAACTGGAAAGCGAACTGGGTGAAGATCTGACTCAATTCGACCCCAATACTCTCTCCACCAATGACATCACCGCCATTTCCCGCACCGACCCCTCCCTGAGTGGAACGATCGGTATCAACACTCCCGATGTAGACCCCAGCAAAGGGTTTGTCGAATTGCCAGATGAAACCGTCGATGTTGCCCGGTTAATCAATGATACCGTGTGTCGTCTCGGTCAGGGAAGTGAGTTCGTGCAAACGGGACGCGGTGGGTTGCCTCCCTCGCCGACTGACCCCCTTACCACCAATGAGGTGTGGGAAGATTGGCGCTTGCCGGGGATTTCGGAAGAAGGTCAAACCCAGGAAAACAACATCAATCGCTCCTTACCCCAGGGCGATCGTATGATTGAGGCACGGGATTGGCAAATGAAAGAGAATGGCGACTTGGCACTCATCGCACCGCCATTGGCAAGTGAGGTGGCGATTGGGGAGGCGATCGCCACAGGTTGTGTGCCGCTACAAGCGAAAATGCGATCGCCATCGGGGGACATCCTGGCGATCGCCGCATTCCCGGACAAACCCAGTTCCCAAACTGTTCAAGTGCAACAGTTCGAGGCGATCGGTAGTACCGTCTTTACCCCTGAACAACTCGCTGCCGTTACCCAACCATTTCTCCAGGACCCCCTCACCTTTGATCGCCTCTTAAATGCGCGATCGGCGATCGCTCAACTTTATCTTGATGCTGGTTATCTCACTTCTGGCGCGTACATTCCCCCGCAAATCGTCCAAAATGGCGTTGTCACCATCCAAGTGGTCGAGGGTCAGTTAGAAAATATCGCCGTTCGCACCAATGGCAGACTCAATGAAAGCTATATTCAACAACGTTTAGAGCGGATTATTTCAGAACCCGTGCATCCCGAACGGGTACTCACCGCGCTGCAATTGCTCCAACTGGATGAAAATATTGAAACTATTTCCGCAGAACTCTCCCCAGGGGTGCGTCCCGGTACTAATTTACTCACCGTAACCGTCAAAGAAAAACCATTGTTGGGGACGCAATTGAGTGTAGATAATAACCGCGCTCCCAGTGTCGGCAGTTTCCGGCAAACGGTGCAAACGAATTTTAGCAATCTCCTGGGATTGGGAGATGTGGCAACGGTTGCTTACACCCACACCGATGGCAGCAATACTTGGGATGTAGTTTATGGCGTTCCCGTGAATGCTCGCAACGGAATGCTGAGTTTTTACTACGGCAGGGGTGATAGTAAAATTGTGGAAGCGCCATTCGATGAATTGGAAATCGAAGCGGATTCTCAAGTTTATGAAATCGCTTATCGGCAACCCTTTCAATCCATTCAGAAAAAAGCGCGAGAAAATGGCGAAGATGAATATGTTTTTCAAGAATTTGCCTTGGGTTTAACCGCTTCGAGACGCAATAGCCAAACTTCTTTGTTAGGAGTAGATTTTCCCCTGTCTCCGGGGGCGAATGATGCGGGAGAAACGCGGATTTCTGCCTTACGATTTTTTCAGGAATGGACGCAACGTCAAGATCGACAAGTTTTCGCAGCGCGTTCCCAATTGAGTTTGGGAGTGGGGTGGTTTGATGCCACAGTCAATGAAAGTGAACCGGATAGTCGCTTTTTGGCATGGCGAGGTCAGGCACAATGGGTGCGAAGAGTGACGGACAATACTTTACTGTTAATGCGAGGGGATCTGCAACTTTCGCCGAATGCTTTATTGCCATTTGAACAGTTTGGTTTAGGAGGTCAAGATCGGATTCGGGGATATCGTCAAGATGCTTTACTGACTGATAATGGTGCGTTAGCTTCCGTGGAATTGCGGTTGCCAATTCCTGTTGTGTCCCAGCGTGGGCGGTTGGTGCAAATTGCACCATTTTTGGATGCGGGGGTGGGTTGGAATAGCGACGATCGCCCCAATCCAGAACAGAATGCATTGTTGTCTGCGGGGGTGGGATTGCGAATGCAGTTTGGCAACCGCTTGACGGCGCGGGTAGATTGGGGTATTCCTTTAGTAAATCTCGATTCGAGAGCGAAAACATGGCAAGAAAACGGGATATATTTTACCATAGTTTCCGATTTATTTTCAAATTAAAATTTAAGCTAATGGTTTGGGCGATTTGCGGACTGATTCTCAGTCTGAATCTGCCAGTATTATCGGCACAAATCGGACAGGGTTTATCAGGGTTTGCAGAAAATGCTCACCCGGCGATTGCTCAATCTATTGAGCCAGAATCGTTATTGGAACGCGCTCGTACTGCTTATCAGAATGAGGAATTTTTAGAAGCGGCACAACTGTTACAACAGGCAGAAGCGATGTTTGGCGATGCGGTTGTTGATCGCGCCGTCAGTTTAAGTTATCTGTCGTTAGTCTATCAAAAATTAGGACAATGGCCGGAAGCAACGGAGGCGATCGCCACCAGTCTAAGTTTATTAGAAAATACAGCTAATGTTCCCCTATCTGTGCTGGCGCAAACCCTCAACGCGCAAGGAAATTTACAATTAGCGCAAGGACAAGCTGAAGCCGCTTTGGAAACGTGGAAACAAGCCGAAATGGCTTATCAAAAATCAGGCGATCGCGAAGGAGTTAGGGGGAGCTTGATGAATCAAGCAAAAGCCTTGGAATCGATGGGATTTTCACGAGCGGCTTGCAATACTGTTCTTGAAGTTTTAGAGGTAGAGGGGTTGACTTGTGAATCCTTAGTTCAGTCGCCCGATCCAGAGTCAACGTCGAAAAAGTCAAATTTAGATGAATTTCTGATCAGTTTACAGCGACAACCCAATTCCGCTATCAAAGCAATGGCACTCCGGAGTTTGGGAAACCTGCTGCGATCGTTTGGTTACTTAGAGCGATCGCAGCAAATTTTGGAACAGAGTTTGCAAGTGACTGAAACCCTACAATCGCCTCAAGAGATAAGTTTATCTTTACTAAATTTAGGGAATACTGCTCGCGCGCAAGAAGATTTTACCCATGCTTTGGCATTCTACAACCAAGCGGCGATCGCCGCTAGTTCTCCAGCCACTCGTTTGCAAGCATACCTCAATCAACTGAGTCTGACTATTGAAGTAGAGCAAATAGCAACAGCCTCACCGATCATCACACAAATTCAATCTGAACTCGACGATCTACCCACCAGCGCAATCGCAGTTTACGCCCGCATTAATTTCGCCCGCAGTCTTTGGGAACTGAGGAATCAAAGCAATCGTTACGATTTGGCCCAAATCGAGGAATTATTAAAAATTGCCGAACAACAAGCTCAAGAACTAGGCGATGACAGACTGCGCTCTCACGCTTTGGGAAATCGCGCTTGGTTGTCCGAACAAAAGGAAGATTGGTTACAGGCGCAACAACTCACCACGGATGCGATTTTTTTAGCTAAAGACGCTCCAGAAATTGCTTATCAGTGGCAATGGCAGATGGCAAGAATTAAACAGAAAAACCAGGAAAATTCCAGCGCTTTGCAATTTTATGATGCGGCCATTGCGAGTTTAAAATTAGTTCGCAAAGATTTAACGGGAATTAATCCAGACATTCAGCTATCCTTCCAGAAACAAATCGATCCCCTCTATCGAGAATTTGTAGACTTGCTGTTACAAGGCGAAAATCCCAGCACCGAAAACTTAGAAAAAGCACGACAGGCGATTGCTGATTTGCAACTGGCAGAATTAGAGAACTTTTTGCGGTGCAGCTTGCAAACTGAAACCCCCGTCGAACTCGATCGCCTTGCAGACGAACATCAGGCAGCAATTATTTATCCGATCATTTTACCCCAACGATTAGCCGTTATCGTTAAACGTCCCGGTTCCTCCGATTTGCTGTATTTCCAGACAGAAATTTTACGGCAGGAAGTCGATCAGAAACTAGATAACCTTAGAAAACAATTAGAAAGAACCTCGATTTCGATTGAGGCTAAACAGCTATCGCAAGAGGTTTATGATTGGTTAATTCAACCGATTGAAACTGCATCTAATTCTCAGATAAACCCCATTAAAACTTTGGTGTTCGTGCTAGAGGGTCGATTGCGGAATATTCCGATGGCAGCTCTATCTAACAGTAACGGAGAATATGTCGTCCAGAAATATGCAGTCGCCCTCAATCTCGGTCTAGAATTAAAAGATCCCCAACCCCTCGCCCAGCAATCTTTAACCGCGCTGTTAGCGGGAATTACCGAACCCTTGCGCGGGATGCCAGCACTCGAATACGCAGATCGAGAACTCAACCTGGTTGAAAACTCTGTGAGTTCAAGTCGCCAACTGCGAAACCAAAAATTTAAAAAAGAAACCTTGGAAAATCAGATCAATTCGCGCTCGTTTGCGATTGTTCACCTTGCTACTCATGGCGAATTTAGTTCCCAACTCGAAAAAACGGGAATTGAAGCATGGGATGGACGGATCAATCTGGATGAATTAAGCACGATTTTCACCCAACAAACCGAAAATCAACCCAGTCCCATCGAACTGTTAGTGTTGAGTGCTTGTAAAACCGCAGAAGGGGACGATCGCGCTGTTTTAGGACTCGCTGGAGTTGCCGTGCGATCGGGTGCTCGGAGTACCGTTGCCTCTCTGTGGTATATCGACGATGAAACTAGCGCCCTTTTAATGAATCGATTTTATTATTATTTGAATGACCCTCGCGCACTCAGCAAAGCAGAAGCGCTGCGTTTGGCACAAGATGATATTCGCAAGGAATTTATCAATAAAAGAGCGCCTTATTATTGGGGCTCGTTTGTGTTGGTTGGCAATTGGTTATAGTCCCGATTGAGGAGGGAGATAAAAGTCCCCCATTCCTCCCATCAGGCGGATGCGATCAGGGTTCTATCACATAACGCTCGACGATCGCTTCATCAGCAAAATCACCCAAGTTAACTGAGTTTAGCAAACTTTGCCAATCTCCTGTGATCTCACTATTCGATGGATTTTGTAACCGCCGATCGCCCAATAGCGTCAGCGCATCATACCAAATTCCCTCAGTGGCATACCCCGCAACTGCTTGCCGGAGTGTCTCATAAGGCATTTCTTGCCGATTTATCCCCTGCCACTGACTGATTTGCTGTGAAGGCGTTACCTGTTGCACCCAACCCTGAACAAACAAATTGTTTAAAGAGGGGCGATCGGGATAGCATACAATTGTCAGTTGCCACCGATAATATTTCCCTAATTCTAGCAGTTTATCCGTAGCAACTGCGGGAATTCCAATCCCAATTATTCCCGGATTTTCCGGTAACGTGATCGTGGTACTATAGAGTTCTTCGGCATTTTCATTGACTAAGGCAAATTCCGCCTGAAGCGGAGCGCGATAGGGTACGAAAAACCAGAATGTGGGAGAACTCGACACTGTATATTCTTCCACATATTCCACCCGGCGATCGCCACTTTCGGTCTGCTCCATCACGATTCGCGAAGGCACTAAAGCTTTTAATGGTTTTGCCACTTCCTCTGGACATAAACTGCCTTCGAGATTACTCGGACGAGTTCCCCCACCCGGTTCTGTATCTCCCGGTTTTCCCTCACCCGAACCATTGGAAGTATCTTCATTATATACCTCTCGCGGAATAAAGCGCAACGGATTAAAGGAGGGTGGGATCTGTCCATTTCCCGGCAGTACCCAATAGCTCAAAGCGGCCATTAAACACGCCAGTATAACCCAAATTTGAATGCTGTTATTAATCTCAATTTTTTTACTCATAATTGGTTAGTTGGTTTGATTCTTTTAATACTTTTTATTAAGGATAAATCGATTGTAAAATAAGACTATACCGCCGCTGGATATCAATGCTAACAACGATGGAACCAAAGGCACCCAAGTACCCCCCATCAAAAGTAAAAAGGAAAGCCCTGATAAAGATGCGATCGCGATTCCTCCTTGGATTCCCAACCGTAGTAACACCGCCATGCTACCGCCCGAGGTGACAAATCCGAGCGCTGAAGGCACTAGAGGCACCCACCATCCCCCTTTTACTAAAAACACAAAGCTGATCGCCAATAAACTCCCGAGTCCAGCACCAAAAACTGTTCCAAAATGCCATCCGGAACGCAAGTAAAACGCCACCAAACCGCCTGCTATAGACCAGCCCCAAATCCACAACATTTCTCCCCATTTCGGCCACACTCCCAATAGCGGACGATTGTCTAAAACCGCACCCAGGATTTGCGCGATCGCGTGAGCTTGAAACACCACGGGCGGCATTTCTAATGTTTTCTTCCGACGCGGATTGGCATCATACAATCGCGAAATATCTTTATCGTAATCAATCGGCGTCAATAAGTTGGTGATCTGGCTAGATGTAGTGCCGATTAATACAATGCGATCGCGAATTAAGTCGGGGTCTATTCTCCCTTGTAAAATATCCGATAGCTCTAATTCCTCTGCAACTTTTCCCCCAGCTCTATAATTCAGCAAAATTTGATGTCCCCGACTATCTAAGTCATGATAGCCTCCACTATCTCTTTCCAGGGTTTGAAAAACCACCCGTCCTAGTTGAAAATACTCCTGTTGCGTTAATTTTAGTTTGATGCCTTCTGCTTGGAGGTAATGTCGTGCCACTTGAAGACTAAAAGATTTATCCGTTTGACAAAGAGAATTGCTAGGAGACATGGCTAAAATATACCGACGTAAAATCCTATCATCATCCGGTAAAATATCTCCAAATCCAAGGCGAAGTGTTTCGGAAACTTCATTGGGTGGTGCGATGCTGGGTTTATCTGGCGTGTGGCTACCCACCGCGCAAAGGGCAATAAAACTAGAATTTTGCTGTAGTTTGGCAGCTAATTCGGGATAATTGACATTCACCGGAAAATCACGATAAAGATTCAAGGCGATCGCACGGGGTTGTAACGGTTCGAGAATTTTTAGCAGCCGATCTAGCTTGTCATCGGGTAGGGAGGTGAGCGGGTTTTGTTCCGGTGATGGCAAATCTTTATCGGTAATTTTGACAATCGTAATCCGCGAATCCAATCCTTCGGAGGGACGCAGTTGCATCAAGCGATCAAAGGCTTTTAATTCCAGTGGTTCTAATACCCCAAGCGCTCGCATTCCCATCACTAAACTGGTCACCAGTACGCTCACAAATAACACCGTACTCACCGTCTGCCAGGGCGATCTCCCAATGGGTTGCGGTGCTGGCACAATCGGTTCCGGTGTGGGTTGAACGATTAAATCCGTCCAATTCAGCGGCTTCACCGCAGGATTTTGACAGATAACTGGCAGCCAAGTTGCACAAGGAAATTCCTTTTCTAACCCTTGCAATCTTTCCCTAGCTTGTCGCACAGCCAGATAAAACGGTTCCCCATGAGAAAATGCCTGGAGAAAATTCTTCAAAAATTCATGAGCAACGCGATCGGGGACGGGTTCGCGCATGACAATTGTTTGGGGAATCTGTAACTCCGCCAGTTCCTGAGCCAATCCCAATCCATCACAAGAGTTGAAAATCGCCAGTTGCAAGCCGCGATTCACCGCTTTTCTCAATCCATATTTCAACTCAGCAATAGATAACTTCTCCCGTTCATTGATATAGATGACCCCCCGTTCGTTTTCGCTCTCACTATGACCGGCAAAAAATAGAATATCCCACTTTTCCTCCCACAAGGAATCGTTAATTTCCCGATACTGCGGTTTGACTAAAAAATTGACTTTGGCCTGGGGCAAATTTTCCAAAATTTGGCGATCGACTGTTGTCTCAATTCCCTCATCATGTCCGAGAATGGCTAAAATTTTCACCTTCTGTTTCGGTACTTTTAATGAGGTAACAGCTTGAACCGAGGGGGGACTCAGAGCCAGTTCAGCCTTAACATAGCGGTCAAAAAAGTCCCATAAATGCCAGGGAAGTTTCTGTAGCTGCCGATCTCCGGTGCGAATCAGGACGCGAATTTCATCCTCCCGGCTTAATTCTTCGCGCAGTCGGCGATCGCAGTGGCGAAATTCTGGGGATTCTAGCCAATCATTGAAGCGATCGCTCAAGACTTCAGCGGCTTCGCAACATTCCTCGATCCGCTTCTCAATCCCGCCATCATAAATAATTTTTTTGGTTTTGATTCGTCGGGAAGGTTCGCCAATGTTGCGATATTTTTCCACCCAATCGTACAGTTGTGTACTCAACTCAGGTGCCCGAGGGAGCTTCCCAGGTAACTCGATCCAAGGGCGATCGCCCTCCAAGCCGATTTCCAGCATCACCCGAACCTCTTGACGCTGGAAATCGCCATCTAGTTTAATGACAACTAATTTTCCCACAATGGCCTCCCCTGACAATCATAGCGGTTTGACTCAGATTATAAAAGCTTCCGTTACGCTCACATCGTCTAAGGTGACTCTAACGCTAAATTGTTCCCCGGGTTCCCCACTAAAATTGAGTTGAATGTTCTTCGTATTTCTGGCTTGCGCTTGCATGACTGCCACCCCTTCTGCATCCAGTATGATTAGGTTTAAACTTGGGGGAAGATACACTCGTTCATCAGTGGGATAGACTTCAATCCAGATGTCCATTTCTGGCGCTTGTGCGGGCTTCATTCCCACCACCAGCGCCACAGTTTCACCCGCACGAGTTAATTCTATTACCTTACCTCGCTTAACACTGGCCCGTCTAACATTAAAGGCCAATTCCGTTTTTTGTGGCCCTAAAATTTCTTCCACTGTATCCCAACCGGCCTCAAAAATATGATGTAGCCATTGGGTTAACTGAATGGCGGGTTTCGGTTGCAGTTGATGGATATAATCTAGGAAATTTTCCAGGGTTTGAAATTGACTCAAAGGAATTTCCTCCATCTCTACGGTTTTGATAAATCCGTATAATGTCGCTTCTCTGGCCGATTCGCTAAACTGCACTGCCACATAACCAATGCGATCGCCCCAAACCTCCGCCGGAATCTCTACAATTTCCGATCCGAGCGACAGGGGACGGCACTCGATTTTTCCGAGATTCTTAAGTTGTAAATCTGCCACATCCGATAGGGTTTGCATCACCGGATCCCAACTGTCACTTTCTTCTAGATCCGTTGTAATTCCCATGCACTTGCAGTAGAAGTTTACCGCTAACACGGCTAAAGTATTGCGATAAACCCGTTCTGCCTTTACTGAATTGGATTGCTGGCGACTAAATTTCCGGGCGATGTCCTGCCAGGAGCGGGTGAGCGGTGTGGTGAATGTTAATTGGTTTCGATGGATGCTAGTCATCATGTTTAATTTCCTGGATAAATTTTAGCTATTCAAGTAATCTTTTAAAATGGAATTAACTTGCTTCAGTTCCCGTTGGTAAAAATCGCTAAGAGTCGCTACTTTTACCCCGGTTTGCACTGATATGTCTTTCCACTTTTTCCCTTCCATTCGCCATTTAAGCAAGGTTTGAAATGTGAAACTTGGATAATTTTTGAGGCGCTTCTGTTTCAATCGGTTTTCTGGATCCTCGAAGATATATTGCCGCAGGAGTTCCGAGGTGGAAGGCTCCGCTTCGTCTTGGGGAATCTGCTCGATCTCATCAGAAGAAGCAATCATTATATCCGGTTTCCCGACTACGGTTTTGATGGCTTCCACGATAAATCGCTTTTTAAGTAGGTAATTGAGCCAATAGATAAATGAGGCTCTGTCCGGATCGTAGCGCTCGATCTGTTGGCAGACAAAAAGCCACAGTTGGGATAGCGCCTCGGCATAAATATCTTCATAGACATGAGAAAATTGCCCTTGGCGCGGGCGGCAGAGTTTCCCAGAGTACGAGATCGCCTCAATCAGCTTCGTTAAAGCCAACTGTCGCTCTTTACTCTGGGGAGGATGCCGCTTCGCCTCCATCGCCAAATTTTGGATTGCCTCGTCCATGACTCAATCTCAATGCACTCTATTTGCCTTGCTTTACCTATTTCTCTGAACGAATTAACGGTTTTTACGGATTATCTCGGATTTGTTTACAAAACTTTATATTTTGGTAATCCCGCCTCAAGCCTTCCCATTTAGTATTGCAAATTGCCAAGAGAGTACAAATAAAAAGGCCGGGATTCAGCCACCACAAAGCGATCGCCTTCTCCCGAACGGAAGAACTCTGGGGATTAAATGTAAAATTTTGTAACAATCTTCGGAAGAACCCGTAAAAAAGCCAAGTCAAGACCGAGAGCAAAGATTAAGGCAAAGGCAGAGATGCTTATCCGCTCCGGCGATCGCCTGTTTCCGGTTTGGCGGTTAACAGGCGATCGCACTCTGACTCCAAACTGAACCCCTTACACCTCTGTTGTTTTGCAAGAGATGAAAAACTTTATGTAAAGTTTTGTAAAAATCTCGGCACTGAACCGTAAAAATCCCGGGATAGCTCAGAGAGATTTAGGTGAAGGCACAAAACAACTGCTTTTGATTGCTTACCAACTTTCAACAATTGCTTGTATTAGGGAGACCGAAGTTTATGTCATCAGCTTCTGTACACCGGAAAAATTGGTTTGTTGCCATTGTTAGGCTCTTATTTTTCAAAAATCATTCGGAAACGGGTCATCATTATGTAACGCCAAACCCTGAGTTTTTGACTTCAGTGGAGCAAGAAGCAATTGTTGATGAAGCAATTCTCCCTCGAAAAGTCGGACGAGTTTATTTTGGCGGTTCTTGGTGGCCTGCTCGTTGCGATCGCGCAATCACCCTGTCTCCCGGTGAAACGGTTTATGTAGTGGGTCGTCATAATATCACCTTATTAGTAGAGCCGGAATCTTTTATAAAACCTACATTCCGCAGGTAAAATAAGAGAGTTCGGAATATTCTAAAACCATGACAGACATAGCATCTGATATCATAGTACAAGATATTGACCACTGTGGCATAGTCTCCGGCATCATTGATGAGATAGGTCTCGTCTATCGCGATTAACCGGGAACTGGAACCCCACCCCCTAACCCTCGTGAGTCCAGGAATCATTGTCAAAGCAATGATTCTCAATGGTTTAGGGTTGGTGAGCGCCCCATTGTACTTATTTCCTCAATTCTTTGTCGGCAAAGCCACAGAACATCTTCTAGGAGAAGGGATAACCCCAGATCTGCTCAATGATGACCGATTAGGTAGAGTGCTAGATGAACTTTATAAAGTAGGCATCACTCAACTATTTGTCAAACTAGCCTTGGCTGCGGCTAAAAAGTTCCAAGTAAATACTCGCTCCTCCCACCTTGATTCAACGTCGTTTCATGTTCATGGGCAATATAGTCGGGAACCTAACCTCACAGGAGAACCCGTTCCGATTGAGATTACTTATGGATACTCAAGAGACCACCGTCCGGACTTAAAACAATTTATCGTAGATTTGATTTGTAGTTCAGACGGGGATGTTCCGCTATATTTAAGAGTAGCCTCCGGCAATGAATCCGACTCAGCTATTTTTGCTAAATTGATGAAAGAATTTAGGGAAAATTGGGACATGGACGGATTATTTGTAGCCGATGCCGCCCTTTATAATCAAGAGAATTTAAAACAAATTAATCATTTGAAATGGGTGTCCCGAGTTCCGGCTTCTTTGAAAGCCGCTAAAGAATTATTGAGCGAACCCGCCGAGTCAGACCTGCAAACTTGTCAATTGGATGGATATCGGATAAAAAGTTGTGAAATCACTTATGAAGAAATTAAACAAAGATGGCTGCTGGTGGAAAGTGAAAAACGGAAAGAGTCTGACTTAAAGCAATTAAAGAAAAAGATTAAAAATTTATCAGAAAAAGCCCAAGCAGAACTTAAAAAATTAAGTCAACAGAAATTCGCTTGTCAACCTGATGCAGAGCAAGCCGTTGAGCAATTCAACAAAAAGCTACGATATCATACAATTACCGGGGTTGAAATATTAACAGTTCCCTATTATACCCAACCCGGAAGACCACCCAAGGGAGCCAAGCCCGCTGGGTATTCTTATCAAATCCAAGGGACTTTATCAGAGAACGAGGCAGCTATAGAACAAGAGAAAATTCGAGCGGGAAGATTTATTCTAGCTACGAACGTCTTGGATGTTAATGAACTGAGCGATGAACAAATATTAGAGGAATACAAAAACCAACAATCGACGGAAAGAGGATTTCGGTTTTTAAAAGACCCGATGTTTTTTACCGATAGTGTATTCCTAAAAAATCCCGAACGAATAGAAGCCCTAGCAATGGTGATGGGATTGTGTTTGTTAGTGTATAGTTTAGGTCAAAGAGCATTAAGAGAGGCTCTGGCTCAAGCAAAAAAGTCGATTAAGAATCAAGTAGGTAAACCCACCACTACCCCAACTCTACGATGGGTTTTTCAATGTTTTCAATCCATTCACTTGCTTACAGTTGATGGAGTCAAGAAAATCACTTATTTAACGGATGAGCGGCGATGGATCCTTCAGTTCCTAGGGGCCTCCTGCCAGAAATATTATTTACTGACTTGATTCAACCTGCGGAATGTGGGATAAAAGCAATGGCCGAGTCTATAAGTTGACAGCTTATAGCGTTCGCCAGTATCAACCCACGCAGCTTTTTTGGAGGCGATCGCCTGTTTCAATCCCTGATAGGGATTAGAGGTTATTGAGACATGATTCAGAACGATATTATATTGATTTTGCTGAGTTTCAATCCCTGATAGGGATTAGAGGTTATTGAGACCGTACACCTATCGCCCCAGGGGAGACCTCCTCAAGTTTCAATCCCTGATAGGGATTAGAGGTTATTGAGACCACTGGTATTTGAAACCGTTGGCATATAAAGTTTTTAAGGTGCATTTGCGCGGTAACTATTCAGGGGGTAGAGGGAGGAGAGAGACCGACTCAGAATGCAAAACCTGCATCAAGAACTCCAACACCGGGCGTTCCTGAAACCGTAAAGATGTGACCACCGTCAGCAAACGTTCCACAAACTCGCTACCCGAGCGAGACCAGGAGCCATAACTCAAGTCACGCCAAATGACTGCCCGGGGGAAAGCGCGCTCGGCTGTATTATTCGTCGGCTCGACGGCGTTCACCTCGACAAACGTCCACAAGGCCGGTTCGAGCTTTAAAATTTGCTCGCAGGTGCGTGCGGTTTTGGCCAAAGGCGTTTGCTCTCGGCTGGAATGACATAGGCTCGCCGCTTCACTCAACAGATGATGAACGCTTTGACGTAGCCGTGCCATAGCCGCTTGGAACAACTCTGTGGATAAAGTTCCATCCCGCACTCGATGCCACCAGTGGAACAGGCGTTTAGTCTGTTTCAGTAGAGCTTCACCAATGTCTTTGGAGACCCCACTGCGTTCAGCCATCCGTTTGAAATCGCGCTTTAAATGCGCCCAACATACTTGTCGTTGCTCAACGGTCCATCCATTGTAGACACTATAACGGTCGCTAACGACTAGGCCTGTGTAGTTCTTTCCTAATAAAGCTTCGGCACTACTACGAGCACGGTTGAGGGTCACTTGATAGACCGCCACGTTATTGCTGACAGCAGTCCACAACCAGGCCGAGGCGTTCTCGGGATTATTGCCGTCACCATTGTTTTGACTCCAACTGGTTTCATCAACGTAAGCCGTTCCACTTTTCATGATGTAAGCTCTGGCTTCATCCACCACTTGGCTGAGTTTCTGACTGACTCGTTGACGGATGCGGTTGACTGTTCCTGTACTCAGGTGCACTTGCCACAAGTCCCTCATTAGGGTTTGTACTTGATTGTGGCTCAGACGATAAGCTCCACTCAGCAGAGCGACCAAACTTTGCAGACGCTCTCCATAACCACTGGGGTTTATATCATTAGGTAACTCGGCCCGAGTGGTTTGACCGCAACACTGGCAGCTTAAGGCGTGAAGTCGGTGTTCCGTTACCACTGGAGCCACCGGAGGAATGTCCACAATCTGATGGCGGTAAGGCTGTGCGTCTTCTCCTGTCAGAGGGGCTTGGCAATGCTTGCAGGTCTCGGGTTGATGGTCGATAATCTCGCTGCACTCACTCGGCTCATATAAGTGTCTTGTAAATCCTTTGTGTCCTTTTTGGCCTCCGCGCTTACGTCGAGGGCGTTTCTCTTGCTTCTTTTCTTTGGCTATCGGAGGCTGTTTGGAGGGCGGGATGGAACTGTTTGAGGCGTTTAGTCCCAGACGTTCTTCAATGGCGGCAATTCGTTGCTCAATATTCCTCACCACATTTTTCACGCTTTCTGGGGTTCTTTCCCAGTCCGCGCGAGGAATTTTGATGCCGCCTATGGTTATGCTCTCTTCCATATTCCCCAGTTTACACCATATCCCCTAGTTTACACCATATCCCCATCCCCCTGAATGGTTACATGGAAAAAATAACGGGAAACGAACTTACATTTGTAGCGACTTAATGAGTTCCGCTTAAAATGGACCCCTGCAACAGCACCGGCGCAATATCAGATAACTGTCGCCATCGGCAGTTATTGACGAGGCGATCGCTGGTGGAATGAATCCGATAACTGTTGCTGCTAAGAGTTGACCCACCTCGCCACACACAGAGTCCCACTAAAACTGGAACGAAAGCTGACCGGGTGGGATGTTCGACTGCTGGCGGGTGTGGTAGCTCAAATGGCAGGTGCTGCACAACGCTATCAAGTTTTCGGGCCGGTTGTCCTCGGGGATGCGGTTGTGGTGATGCACGTTCAGCATGAGTTTGCCCCGTTCCGATTTGCTCAGATGGTTCTTGGGGTCACCGGGACGGAGGCACTGGAGGCCACATTTGGAGCAGCGCCATCCGGCTTGTTCTTTGATAGCTAGGGCGATCGCTTGCCAATCTTGGGAGTATCTGGAGTTTGACATCGGCGTAGCTCGGTTATTAAACAGCAAAGACTGAACACATTCGGTTTGCGCCGTCTCCATTATCTAACATTCTCGTCTTTAGATTGTTAACCAGACCAACCCCACAACCGCTACTCGCCTGGGTTGTAGTTGTAACGGCGATCGCATCTGGGGCTGATTTGCATCACCGACCGACGAGAGCAACCGTGCCAATCTTGGGTAAATTTAGCTGCACTGCAAGTTTTCTAAAATCTGTTCGTTAGGCAATTATAACAGTTGATTAGATTGTTAAGCAGGATTTTGAATGAAAACAATGAGGTAGTTAACTTTCTAAAACTTTAGCTCGTTCAAAACATAGAAATTGTCGAGGAATTATTTTTAAAATATGTTGGAAAAAATCAACAAATCGATTAACTTGTTTATGCAGAACTGGATGCTATTTAGCATGATTGTTCTTACGGTGTGGCTACCTGCTTCCATCTTGCTCGTTTATCTGCGCTGGTATGTCTTTCCAGAGATGACCGGAGGCGATGAGCTTCAAATACTTGCCAAAGAGTACCGAGTTCAGGGTTTAATTGAAACTATATTTGGCCCATTCTGCACCGGAGCCTTGATTTATGCTCTGGCTCAAATTAAGCAAGACGCGATGCCCACCTACGGCGAGTGCATGGCTCATGCGGCTAGAAGAAGTTTTAAGCTAGTTGGGACCCGTATTGGCACTGGATTGATTGTGGTGGGGGGCTTTCTGCTTCTGATTGTGCCAGGAATCATTCTGGCGTTGCGGTATGCCCTAACTGATACCGTGGTGACCCTAGACCGAATTGATGGGGCTAATGCTCGCAAGTATAGCGCCCAACTTACCGAAGGAAAGCGAGGAGAACTGTTAGGGACTATGATTATCAGTTTTTCTTTAGTGTTACTGGCTTCAGTATTTGTTTCGTTACTATTTTCCATGTTCATATCTGAGGCAGAAGGTGGAATTTTTGTCTTGGATGTTCTTTATGAATGTCTTATTCAACTCGCAATTACGGTAATTACAACTACTATTTTATTCTTGTTTTACTGGGAGTCAAAAGAACAAGAGTCGTAATTTTTAATGCAAAATTAGTTGTTTTAGATTGTCAGCATTTACCTCTCGATAGCCAAAGTGAAAACGATTTCAGTTTGGGCTGAGGGAGCGGGTAGGGTTCGAGTTGAAGCGATCGCATCTTAAGAAGGAGAACTAATCTAGACAATCCAATCAATCCGCAGTGCCGCACAGCAGAACTATTTTGTAGGCGATCGCCACACCAGACCCGAACCCAATCTGCACGATAGAACGAATCCGCCGTGCGGTAAGCGCAGCCCGGGCGTAGGCGATCGCATCCCAAGACCTGCACTCACTCTGCCCAATGGAATCAACCCGCAACACGACTGCTACCTAGGACTCAGCCTGAGAAACCCCAAAGGTGTTTTCTTGACACCCATGCTGGTTAAAAGGGGTGTGCTCTGAAGGCATTAGAAATTTGTTTTGCCAATTCCTAGAAAAGCAGAGCAGAAGAGAAAGATAATCTTCTAATGTACATCTCGTTTACCTTCTTACAGAACCTTAGCTCCACCATCCGTTCCTTTCATTTCTCCTTTGATATCGAAACCGGCACCACAGGTTAATCCTGATGACCAACCTGACCAGTTAATTGTAACTGAGATCTTGCACCATTCTCAACAACGAGGGATCTGCGAAGGGGTTTCCATCATCAGGGGATCCCCGTGCTAGGGAAACCCCTTTCGCCTAAACAAGTCTAAGCTGAGTTTTTAATCTAGCCTCGATAAGCTTTTGACCGTGCTAGGGAAACCACTTTCGCCTAAACCCTTGCTATAGCGAGCATTTCACTCGGATGGAGCCAATTGAGTTCCCCAGAGAAATCTGTGTGGCCCCAGTTGCCAAAAGGGGGCCACATATGCAAAAAAGAAGACATAAACCTCCCTTGTACCAGTAAAGATGGATAGCATTCTGACTCCGGCAATAGCCCTTGTTAACGTTCTGTTAAACATCATGCCATCTATTTACCAAAGAGACAGCATCCAAGCTCTATTTGGACTATTTTTAGAAGGAAATGGATATCCTTTACCCCAACATTGTAAAAACAAGTCGGCTAGTGCTTTAAGTCGCTTTTTGAATCACTATAACTGGTCTACTCGGGCTGTGATTAAAGCGGTCCGAGCAGATATTGTGGCTCAAATTAAAACCTTAGCACCAACTGGTCGCCGTCCAATTTTATATCTAATACTTGACATGACGACTCTGGAAAAAGTCGGTCAATTTACGGGACTCAACAATCTGATTCGAGTCTATAACGGTAAACGGGGACTCCATTTACTGGTTCTCTACATATTATTGGGTGAGCGCCGTCTCCCTTGGGGTTTTAAAGTCTATAGAGGAAAAGACGAAACTCCCCCGGTTCAACTAGCTATTCGCCTTTTAAATACTCTCCCCCAATCCCTGAAAACCCGTTTTGAAATCAGGATTTTGGCGGATACAGCTTTTGGAAGTATTGATTTTCTGAAGTGGATAAACCAACATAAAAACTATCATGGTATTGTCGGAATCAGAAAGGATAGACGCTTATCGGATGGTATAAGGGTATCAGAGGTTAGTAAAAGGGGCCAGCAGGTTGTTCTTCATGGGATAGACTTCCCCGTCACCCTTTCTTGGTATTGGGTAAAAAAAGAAAATGGCCAAAAAGAAAAACGCTTTGTTATTTCTACCAAACCTCTTTCAGCCGTCTACATTACTATGTTGGGTAGACGACGGTGGAACATAGAAGGCTTTTTTAAAGTCGCCAAACACCGATTTGGTTTGCATCGCTTTGGTCAAGGTACTCTTAAAGGCGTTTATCGCTGGATCATTTTATCCATGATCGCTTACTTACTGGCTCATTATGCCTGTCTATGGTCTGGGTCAACAACTCGAACTGATTGGGGTGAGGCATCAAAACTAGCAAAAGAAACTTTATTTCCCCGCCTCGTTTTACGGATGCTACTCATTGAGATCAAGGAAAAAGCATGGATAGCTCGACAACAGGGGTTAGATATCAGGATCACCACCACTAGGCCCTGTCTGGCTAATTGAGAATGGTGCAAGATCTCAGTTGTAATAAACTTTGCGCCATGTTTTCCGGGTCCAAACATAACAAGGCGATCTCCTGACCAACCATGACCCACAACCAATCCCATACCTGCATGAAGCGCATCTCCGGCAAAGTCTTGAATTTTGATGGGTTTTGTCGTTGAAAAGGGTTCAAAATCACTCTCTGTACTATGCCCCACTGGAATTTCCTTGATTCGCTTGATTGGGCAGAATGCTCCTAGCCCAGCCCCTCCATAGACAAAATTCATCTTTAGTTTTCGACCTTTGTTTCCTGGTTTTCGCATCCGAATTTCAATTTTGCCACTTTTTCCTGTTCCTAGGCTAATCATTCCTGTATCCATGTGCAAAATTTTCGCTTCCCATTCATCTGCTCTATCATTTTTGTAATCTTTAGGTTTCGATGGCTTTTCGGGGATGCAGAGCAAATCTGTGCAAACAGGAGGTTCATCACTTTCAGGCCATTTAACCCACATTCCGCAGGTTGAATCAAGTCAGTAAATAATATTTCTGGCAGGAGGCCCCTAGGAACTGAAGGATCCATCGCCGCTCATCAGTTAAATAGGTGATTTTCTTCACGCCATCAACCGTAAGCAGATGAATGGATTGAAAACATTGAAAAACCCATCGTAGAGTTGGGGTAGTGGTGGGTTTACCTACTTGATTCTTAATCGACTTTTTTGCTTGAGCCAGAGCCTCTCTTAATGCTCTTTGACCTAAACTATACACTAACAAACACAATCCCATCACCATTGCTAGGGCTTCTATTCGTTCGGAATTTTTTAGGAATACACTATCGGTAAAAAACATCGGGTCTTTTAAAAACCGAAATCCTCTTTCCGTCGATTGTTGGTTTTTGTATTCCTCTAATATTTGTTCATCGCTCAGTTCATTAACATCCAAGACGTTCGTAGCCAGAATAAATCTTCCCGCTCGAATTTTCTCTTGTTCTATAGCTGCCTCATTCTCTGATAAAGTCCCTTGGATTTGATAACAATACCCAGCGGGCTTGGCTCCCTTGGGTGGTCTTCCGGGTTGGGTATAATAGGGAACTGTTAATATTTCAAACCCGGTAATTGTATGATATCGTAGCTTCTTGTTGAATTGCTCAACGGCTTGCTCTGCATCAGGTTGACAAGCAAATTTCTGTTGACTTAATTTCTTAAGTTCTGCTCGGCCTTTTTCTGCTAAATTTTTAATTTTTTTCTTTAATTGCTTTAAGTCAGACTCTTTCCGTTTTTCACTTTCGACTAGCAACCATCTTTGTTTAATATCTTCATAAGTGATTTCACAACTTTTTATCCGATATCCATCCAATTGACATTTTTTTAGGTCTGACTCGGCGGGTTCGCTCAACAATTCTTTAGCTGCTTTTAAAGAAGCCGGAACTCTTGACACCCATTTCAAATGATTAATTTGTCTTAAGTTTTCTTGATTATAAAGGGCGGCATCGGCTACAAATAATCCGTCCATATCCCAGTTTTCCCTAAATTCTTTCATCAATTTAGCAAAAATGGCTGAGTCGGATTCATTACCGGAGGCTACTCTTAAATATAGCGGTATATCTCCGTCCGAACTACAAATCAAATCTACGATAAATTGTTTTAAGTCCGGGCGGTGGTCTCTTGAGTATCCATAAGTAATCTCAATCGGAACGGGTTCTCCTGTTAGGTTAGGTTCCCTCAGATATTGCCCATGAACATGAAACGATGTTGAATCAAGGTGCTTGCTTCGGGTATTTACTCGGAACTTTTTAGCCGCCGCCAAGGCCACTTTTACAAATAGTTGAGTGATGCCTACTTTATAGAGTTCATCTAGCACTCTACCTAATCGGTCATCATTGAGCATCTCTGGGGTTATCCCCTCTCCGAGAAGATGTTCAGTCGCTTTGCCGACAAAGAATTGGGGAAATAAGTACAATGGGGCGCTCACCAACCCTAAACCATTGAGAATCATTGCTTTGACAACGATTCCTGGACTCACCAGCGTCAGGGGGTGAGGCTCCAGTTCTCGGTTAATCAGCTCGACGAGCCCTATCTCATCAATGATGCCGGAGACTATGCCACAGTGGTCAATATCTTGTACTATGATATCAGATGCTATGTCTGTCATGGTTTTAGAATATTCAATACTCTCCTATTTTACCTGCGGAATGTGGGATTTAAGTTGTTGAATTTCGATATCAACTCGGCGGAAAGGCTTGAGTTCTTCTGCTGTTGTTCCATTTTGAGGCCGCTCAATTTCACTCAGAGGAACATCTAGTGCTTCATAATCGTTTACATTTTGCTTGTCAAGCAGGGTTAGGAGCCGTGATGAAACTGAAGCCGTTCGCAGGTCTGTCAGTTGAAGGTTGTAATCTACTGCTTCACGCTTGTCGGCATAGCCATAAAAATTTAGAGAGACAAATTCTGCACCCTCTAAAGCATTTGCCAGTAAAAACAAAATCCCTATATCTTGCGAATCTAACTTAGAATCATTGGTAGGAAAATAAATTTGAGCTACCGGATTTTTACGGGGATTGAATTCGCTTTTACCCTGTGCTTTATCTCCGCCTACTTCTGAGGGTGTAACAGGTTGGGATGGACGGGTTACTCCCATATAGACATCCATAGCTTCTAATGTTATAGGACCAATAACACCATCAACATTTAAAGAAAAAGGTTCTCCCGTACTTAGTGTGCTAAAATATTGCTAAATAATTACTTTTAAAACTTTTATTTTTGCAAGCTTTGGCCCTAAAACTCAAGCCAGAGTTGACTTTGGGCAAATTTTAAGTTATAATAGAATAACGCAGTTTAGCCACAAAGTAAAATATTTATGCCTTCTAAAGCTCAGTGTCACAGTATGTCTCAACTATTGGATTTGGCCGGAGTCTGGGTCAAAGATTATAAAATTCATAAAGAAATCGGCTTGGTTTTACAAATAGAATCACTACAGAAGTTGGCTGTTTGTCCCTTATGCGGGCATCAAAGTAATAAGCTTCATCAAAATCATTGGTATTTAGTTAAAGATTTACCTTTCAGTCAACATCCTACTTACTTGAGAGTCAATCGTCGGCAATTCAAATGCCAAACCTGCCAAAAACCTTTTAGTGAATCTCTCGATTATGTTAACCCTAAAAGAAATTATACCAAAAGGTTAACTTTAAAAATTGTTGAAGAAGTGTTGGAGAGTAATATTCAAAGTGTAGCTCGACGATATCAGGTCACTGAAGAGGAAATTCAAACGATGCTATCAGATGTCGGTTCTGAATTATTACAAGAAAAACCTGCCCCATTTCGTCGTTTGGGAATTGATGAAATTTCTCAAAGAAAAGGACAAGGCAATTATTGTGCTGTTTTAGTAGATATAGATGCAGGAAAACCTGTAGGAATTGTGGATTCTAGACGAAAAGAAGAATTGCTCAAAGTCTTGCAGGGATGGGGTTCAGAGATTTTAAACTTTATAGAAGAAGTGAGTATAGATTTGTGGATGCCCTATAAAACACTGGTGGAAGAATTGCTTCCTCATGCTCAAATAGTTGCCGATAGATTTCATTTAATGAAAGGACTCAATGAAGAGTTAGATAGTCAGAGAAAATTTGAAAAATATTTAATAAACTCTCAAGAAAATTATCCTGAAAAGTCGGACTTGATTTCGGCAATTAACAAAAGCAAATATCCTCTTGTTAAAAACGAGAAAGATTTAACTGAAAAGCAAAATAAAAAATTAAAAGAGGTGAAATTAAAGTTTCCTCAACTCGCTATCATGCACGATTTAAAAGAAGAGTTTAGAGATATATTTGAATCAAAACAGCAAGGAACAGAGGGATTGGTTAAGTTGGTAGATTGGCTGTTTAAAGCTCAACAATCTTTTCCCACCTTTACGAAAACAGTTATTCGATGGTTTCCAGAAATTGTCAACTATTTTGAGAATCGCACCAGTAATGGAGTGGTAGAAGGAATTAACAACAAACTGAAAGTCATTAAAAAATCTGCCTATGGTTTACCTAAGTTTGAAAATTTTAGGTTGAGAAGCCTATTAAATTGGATGTTTACTTAA

Protein sequences of DBSCAN-SWA_3

>NC_019693|3444735:3506658|3452282_3452738_-|WP_015149035.1|DBSCAN-SWA
MESFQPWLSYVGIGVGVIVGGIVLIWISVSLIIFSKTKGLPQAIGAFFAQIGQGDINGAYQSTSDRFKSKTSKQQFAKFIKTHKLNQYQRTTMSIPTTEEDVHCLDVTVISKTGREVLVQMKLVKQDKVWTVDDLTYQYNSSKKATTAAKK
>NC_019693|3444735:3506658|3465040_3465772_+|WP_015149049.1|DBSCAN-SWA
MTYCLRIADIPTNERPRERLMAYGPKSLATAELIAMLLGTGQGPGKLSAVGLGQYILQKLGENQRDPLEVLREMSPQELMEIPGVGPAKATTILAAIELGKRTFYSRPPERKEIDSPEAAAAALSHELMWQTQERFALLLLDVKNRLIGTKLLTIGTATETLAHPREIFREVLRHGATRAIISHNHPSGSLEPSPEDIQLTRQLLQAGQLLQIPLLDHLILGNGDFQSLRKICGLWQEYPQGD
>NC_019693|3444735:3506658|3497504_3498956_-|WP_015149066.1|transposase|DBSCAN-SWA
MEESITIGGIKIPRADWERTPESVKNVVRNIEQRIAAIEERLGLNASNSSIPPSKQPPIAKEKKQEKRPRRKRGGQKGHKGFTRHLYEPSECSEIIDHQPETCKHCQAPLTGEDAQPYRHQIVDIPPVAPVVTEHRLHALSCQCCGQTTRAELPNDINPSGYGERLQSLVALLSGAYRLSHNQVQTLMRDLWQVHLSTGTVNRIRQRVSQKLSQVVDEARAYIMKSGTAYVDETSWSQNNGDGNNPENASAWLWTAVSNNVAVYQVTLNRARSSAEALLGKNYTGLVVSDRYSVYNGWTVEQRQVCWAHLKRDFKRMAERSGVSKDIGEALLKQTKRLFHWWHRVRDGTLSTELFQAAMARLRQSVHHLLSEAASLCHSSREQTPLAKTARTCEQILKLEPALWTFVEVNAVEPTNNTAERAFPRAVIWRDLSYGSWSRSGSEFVERLLTVVTSLRFQERPVLEFLMQVLHSESVSLLPLPPE
>NC_019693|3444735:3506658|3494000_3494612_-|WP_015149063.1|DBSCAN-SWA
MDEAIQNLAMEAKRHPPQSKERQLALTKLIEAISYSGKLCRPRQGQFSHVYEDIYAEALSQLWLFVCQQIERYDPDRASFIYWLNYLLKKRFIVEAIKTVVGKPDIMIASSDEIEQIPQDEAEPSTSELLRQYIFEDPENRLKQKRLKNYPSFTFQTLLKWRMEGKKWKDISVQTGVKVATLSDFYQRELKQVNSILKDYLNS
>NC_019693|3444735:3506658|3463406_3463730_-|WP_015149046.1|DBSCAN-SWA
MDTSQTYRDIVKQVILGYAQLKPSHGDIRLDPVFDETRDRYALMQVGWDRGRRVRGNLIYVTLQDGKVYIEYDGMERSITEELIHKGIPNNQIVLAFLSEDEKVPVG
>NC_019693|3444735:3506658|3456636_3457578_-|WP_156824060.1|DBSCAN-SWA
MDMDEERAIQPRQQQERVMDSGFFWITRIFAFAIAGILVWIAIQVAIEAIPAIQAFGFNFVTSSSWNPVRDEYGVWPMIYGTLVSSALGLLFAVPLGVGTAIFLSEDFLPKSVQTVLVFMVELLAAIPSVVYGLWGIFVLIPFLQPIGLFLHNTLGFLPIFSTSPVGPGMLPAGIILTIMILPIITAISRDSLASLPPELRQASLGLGATRWETIIRVLIPAAFSGIVGGIMLGLGRAMGETMAVTMIIGNSNDMKFSLLAPANTISSLLANQFAEASGLQISALMYAGLVLFLLTLVVNICAELIVRKVKKF
>NC_019693|3444735:3506658|3447569_3449285_-|WP_015149032.1|protease|DBSCAN-SWA
MSETSFPKAGRSGTTGVKLMMTGVGGNLAFASVVTMTLMFGMVFVLCLGVSLILNSENPGMGLVISIVGTLVFNIAAFFLSPWIMDLTQQWLYGTRWIDLTELNRKSPESAEIIRQICADKNLKQPRLGIIDDQNPTAFTYGSLPNSARLVVSEGLFTYLDDDETATVYAHELGHIVHWDFAVMTVASTLVQITYLIYVYASRMGRGGGKAKDIAGQVAMAAYIFYLVGTYLLLYLSRTREYFADRFAAETTGNPNALSRALVKIAYGLVEEGQKATEPSRLVEGTRALGIYDHKAATSTGTTYRISSKPEQIGRVFLWDMFNPWGWWMELNSTHPLTGKRVRALSTYAEQLGLDIEFDMGRIMGEGRTLSKSKLYGTFVGDLFLYMAPMIGLIAGAIAWFVLPIPPGDFALLAYPLLGLGIGLLVKTLVMFPNFDRAPETDILTLMADPYASPLRGKPAKLKGELIGRGDAGYTFGSDLKLQDPSGLLFLRYASRFGPIGNFLFGMKKVKSLIGMQVHTLGWFRRGVAPWMDLIQLETQNETKVNSYHRFWSFLMSGGMIIGGIVLLFIV
>NC_019693|3444735:3506658|3446530_3447487_-|WP_015149031.1|DBSCAN-SWA
MSYEREKQVAIDAAIAAAKLCQAVRREIPVAMEKIDKSPVTVADYGSQALICKALDAAFPEDAIVGEEDATDLRSNSEQLTKVTHHVQSLVPDATPEQVADWIDRGNGEVGGRFWTLDPIDGTKGFLRQDQYAVAIALIEDNEVKVGVMACPALNLESGEEGTLFVAVRGEGATMQAISGGTWRSLRVVAADDVENMRFVESVEASHGDQSRQTSVAKAVGFTAESVRMDSQAKYGIVASGQAALYMRLPSPKTPDYRENIWDHAAGAIVVEEAGGRVTDMHGNSLPFGMGKKMVNNQGIVVSNGTIHDTVLKALQES
>NC_019693|3444735:3506658|3493070_3493976_-|WP_052315743.1|DBSCAN-SWA
MTSIHRNQLTFTTPLTRSWQDIARKFSRQQSNSVKAERVYRNTLAVLAVNFYCKCMGITTDLEESDSWDPVMQTLSDVADLQLKNLGKIECRPLSLGSEIVEIPAEVWGDRIGYVAVQFSESAREATLYGFIKTVEMEEIPLSQFQTLENFLDYIHQLQPKPAIQLTQWLHHIFEAGWDTVEEILGPQKTELAFNVRRASVKRGKVIELTRAGETVALVVGMKPAQAPEMDIWIEVYPTDERVYLPPSLNLIILDAEGVAVMQAQARNTKNIQLNFSGEPGEQFSVRVTLDDVSVTEAFII
>NC_019693|3444735:3506658|3490520_3493037_-|WP_015149061.1|DBSCAN-SWA
MGKLVVIKLDGDFQRQEVRVMLEIGLEGDRPWIELPGKLPRAPELSTQLYDWVEKYRNIGEPSRRIKTKKIIYDGGIEKRIEECCEAAEVLSDRFNDWLESPEFRHCDRRLREELSREDEIRVLIRTGDRQLQKLPWHLWDFFDRYVKAELALSPPSVQAVTSLKVPKQKVKILAILGHDEGIETTVDRQILENLPQAKVNFLVKPQYREINDSLWEEKWDILFFAGHSESENERGVIYINEREKLSIAELKYGLRKAVNRGLQLAIFNSCDGLGLAQELAELQIPQTIVMREPVPDRVAHEFLKNFLQAFSHGEPFYLAVRQARERLQGLEKEFPCATWLPVICQNPAVKPLNWTDLIVQPTPEPIVPAPQPIGRSPWQTVSTVLFVSVLVTSLVMGMRALGVLEPLELKAFDRLMQLRPSEGLDSRITIVKITDKDLPSPEQNPLTSLPDDKLDRLLKILEPLQPRAIALNLYRDFPVNVNYPELAAKLQQNSSFIALCAVGSHTPDKPSIAPPNEVSETLRLGFGDILPDDDRILRRYILAMSPSNSLCQTDKSFSLQVARHYLQAEGIKLKLTQQEYFQLGRVVFQTLERDSGGYHDLDSRGHQILLNYRAGGKVAEELELSDILQGRIDPDLIRDRIVLIGTTSSQITNLLTPIDYDKDISRLYDANPRRKKTLEMPPVVFQAHAIAQILGAVLDNRPLLGVWPKWGEMLWIWGWSIAGGLVAFYLRSGWHFGTVFGAGLGSLLAISFVFLVKGGWWVPLVPSALGFVTSGGSMAVLLRLGIQGGIAIASLSGLSFLLLMGGTWVPLVPSLLALISSGGIVLFYNRFILNKKY
>NC_019693|3444735:3506658|3472580_3481184_+|WP_015149055.1|DBSCAN-SWA
MPGINDNEFNLVGGLTDDFLEDKLVSPLPSILAAGSELSLDADRLGEALTPEPFVEGEDEFPQMVLEKGNLLDKEVIVSSTPDNSDSDSLTNYRQDDEVTSLIDIDEDDPLINGGDVSSEGSLSEEPSESDTEESDRLSDNPSESSESDNSDRKTLAEDRDEFLEAEPPTLETDDEAIALDNGGAVSEEESHSEEPSNSNTEEIEGLDNPSESSESDKSDRKTLAEDRDESSEAEPLELETNDEAIALDNSPHLISDEETPASDTNSLKSSLSDVPNEDSGESALSSAVTASSGETDIDVEVEDTKENTEADIKENPESKSLLNSDRETDSDSENNNETSITDATASSDGDDSNLPKNLENFANVTFDSGVFVVGESGKVQFDYLFDGGGYEGKLAAFSLTGMEPFQQQGLEAFIQEALRRSLSQSLEGHVVISDRTEGARFSGELGEANQNRGDYQGIKTLDMTPGDKFGVLLVPQGTLQEVWEQLEAGNFESVSAAKRPLFSMSTANPEDGFNFGQIADVFGDGSTFVFEDLRVDKGTDLDYNDVIFQVRGAIAEAAFLKDVINPNKNWLETGELSKAIENYAKREVDDSTEEETEPQTPIAETLPDSVKYALLRSQDLENYDPKALETTRQWVVGVTPGYSASEFATLYNAEDIGATGHIPDTYIWNFSEFGNAQQVAKRLSDLKGVEFAYPLTRVQLEPLSTPNDPLFNQQWHLENTGQTGGTAGVDANIITVWDEITGEGIKIAIVDDGVQHTHPDLSDRYRPDLSLDLNEGDILHRNYDTDPAPFSHQTIASNFANPQPLIDNDWSWELPTLDVGLKGVIDHAKLKFNFDHPAPNELDIYLYSPKGTDLLLPPITTSGEFEIDTALFNGEEANGEWRLMFEDRVLGNSGTLNNWSLELQASNKHGTSVAGVAVGTSNNNLGISGIAPNAEWGGIRLIADKVTDIQIADALYSNLNQSIQVYNNSWKPPAFWFGEQGQGLMALHQGVTTGRGDLGNIYLFGAGNDGENVENINYNAYANSRYTIAVGAVDSRGRKPLYSQEGAALFVSAPSSGNTGGITTTDLLGDHGWNSEGSGKFGLNYTDLDYTNDFGGTSSATPVVSGVVALMLEANPNLTWRDVQHILAETANRNAIADSSANWSGNDGDRIRHSDRYGFGLVDAASAVAAASTWTSVAPEVAITSGTLTVDRAIPDNTFAGITQEFTLDRNITLESVEVVFDADHPYRGDLWIELTAPDGTKSLLANPSNDDGHDYQNWVFNSVRHWGDSSQGTWQLRVRDRYPSYSGSWNSWKLNFYGTQPTVTLEASDTNASETGDAGEYTFIRTGDITHPLTVSYAIAGSATNTIDYTELTGSITIPAGSDRITLPLSAIDDEEVEGTETVVLTLAAGSAYNVGTQNMGTVEIADNDLPNVPPTLTPQTATQTYTEDIPLDLIDLVVSDPDAGDTLTVELQLDPTAGILTTGTVDGISSVYNSATGLWQVSGDVTTVNAVLADVRFIPTENYYGEVTIATSVTDNIAPAVTGAIALSGTPVNDAPALSQITTLSGATQGLPFTISYEDLLNASDASDVEGDAITFQIAGITSGTFTKNGQSVTVGETELAAGESLIWYPDTMGNAVPAFAVTAFDGVDESQNAVNVAIAVDELPTIIINATDAIASESGDRGQFTILRSGNTDNQLTVNLAASGNAVNGSDYSAIPNSITIPAGQSSIAIDITAIDDSLVEGDEQVILTLSVGSDYQIGGQNSATVTIVDNDNEPLPMVMLAPGNLNASESGVAGNLLVFRNNGLGQELTVNYSLGGTAENGVDYQPLTGSVTIDANSFFATIQIIPIDDSEFEGTETVSVNLVAGAGYQVSPNGYEVQIADNDKPSVSLVATDGEASEDGDLGYMTLTRTGITTNPLTVNYAIGGTATNGMDYTALSGSIEIPAGLSSITIPIQAIDDNSVEGDETVVLTLTDNSAYNVGTDKTATVSIIENDLEPFTPVESILTGVDNGSVAWGDYDGDGDLDLLITGRRGMSRFSKIYQNNGSGNFIDIDAGLIGVDNGSVAWGDYDGDGDLDILLTGDSNGNSNGIAKIYRNDGGNFIDIAANLPGVVNSSVEWGDYDNDGDLDILLTGHHFSSGGYGSGGYGGVDVGTISQIYRNDDGTFIESGISLIGVGSGSAAWGDYDRDGDLDIVLTGITDDGSSIVGVSKIYRNDSGSFTDIGAMLPEISWSSAAWGDYDNDGDLDLVITGFNDTVGEVSQLYQNNEGTFIQVETNLPGITDSAVAWGDYDNDGDLDILLVGQKESSNSVATIYRNDGDNEFTDIDANLKLMPPNVYNTGDRFAVWGDYDRDGNLDILQTGLDSSNNFIAQIYRNNSVIANNSPTSPDGLNALVHENSVTLSWEPGTDSETPQNGLTYNLRVGTTPGASDIVSPMSNSDGTRQLAQMGNVHQNTNWTINNLKPGTYYWSVQAVDSAFAGSEFATEGTFTMTAIGEIQWIQQIGTASFDDSREVAADKWGNVYITGYTLGSLGGTNAGNHDAILTKYDTNGNLLWTRQLGTPEVDVAFGVATDSVGNVYITGQTAGALEGTNAGNDDAFVTKYDTNGDLLWTRQLGTPGVDIAYGVATDHDDNFYITGYTTGSLASPNAGEYDAFIAKYDSNGNQLWSQQLGSLQTDIARGVAIDGGGNVYISGRTTGSLDGNNAGNFDAFFAKYDRDGNLVWIRQLGTSGWDQSPGISTDKNGNIYITGYTTGNLEGVNAGTRDIFVTKYDPSGNLLWTEQLGTSSLDYSYGSATDSAGNVYITGHTTGSLEGENSGGYDVFAIKLDSNGNQVWIQQFGTSAIDYSRGIATDPAGNIYITGSTQGSFGQTTAGNSDVWVAKLS
>NC_019693|3444735:3506658|3482582_3486905_+|WP_015149058.1|DBSCAN-SWA
MGHRQRSQISGSSLTGKLAILSIALCLFPPIAVAQIVPDATLPVNSIVTPDGDALIIEGGTSSGFNLFHSFQEFSIPTDTAAFFNNDPTIANIFTRITGISVSNIDGVLATTGTANLFLLNPNGIVFGPNAQLSIGGSFLATTADRFTFADRTQFGADVQTPPQLTISTPIGLQYGSNPGDIAVGGAELQISPGETLTLAGGNVFLEGAALLAESGRIELSSAIAGELSLIPLQQPSETASTVTYGDIQLSQGSAIDTSGEAGGDIQLQGRRIELRDGSLLQTTTLGEAPGGNLTIRAAESLKLSGNDLAGFPSGLLAETAGAGDGGNIGIVARRVVFQDGGQASASALAGSTGNGGNVRVNALEFIEISGSTGAIADPMTGEEFGLKSGLFTEAQGAGNGGNIEINSPRITLRDGAQVSAVTIGAGNGGNIAIAATTVELVGISGILVNADIGSSGDGGDIAIATNQAIVRDGAQIASTTFGEGDAGDIRLNASELLQVSGTTADFFGGIFAEVAQESTGNGGNITLESDRLLVDNGASISTSTTGQGQGGILTIYSQSLTVRGGQIAAATVGEFPGGSISIVSDSVELSGTTPDGFPSGIFTQTLGSGNAGDLTISSSQLTIRDGAKLSVSGEATGNAGSLTVNSDALELQNAAILTGETVSGQGGNIGINADTIILRGNSNISTTAGTQDNPGNGGNITIDTEAIAGLENSNISANAFNGSGGAIAIATDVILGLEAKTREQLESELGEDLTQFDPNTLSTNDITAISRTDPSLSGTIGINTPDVDPSKGFVELPDETVDVARLINDTVCRLGQGSEFVQTGRGGLPPSPTDPLTTNEVWEDWRLPGISEEGQTQENNINRSLPQGDRMIEARDWQMKENGDLALIAPPLASEVAIGEAIATGCVPLQAKMRSPSGDILAIAAFPDKPSSQTVQVQQFEAIGSTVFTPEQLAAVTQPFLQDPLTFDRLLNARSAIAQLYLDAGYLTSGAYIPPQIVQNGVVTIQVVEGQLENIAVRTNGRLNESYIQQRLERIISEPVHPERVLTALQLLQLDENIETISAELSPGVRPGTNLLTVTVKEKPLLGTQLSVDNNRAPSVGSFRQTVQTNFSNLLGLGDVATVAYTHTDGSNTWDVVYGVPVNARNGMLSFYYGRGDSKIVEAPFDELEIEADSQVYEIAYRQPFQSIQKKARENGEDEYVFQEFALGLTASRRNSQTSLLGVDFPLSPGANDAGETRISALRFFQEWTQRQDRQVFAARSQLSLGVGWFDATVNESEPDSRFLAWRGQAQWVRRVTDNTLLLMRGDLQLSPNALLPFEQFGLGGQDRIRGYRQDALLTDNGALASVELRLPIPVVSQRGRLVQIAPFLDAGVGWNSDDRPNPEQNALLSAGVGLRMQFGNRLTARVDWGIPLVNLDSRAKTWQENGIYFTIVSDLFSN
>NC_019693|3444735:3506658|3463696_3464164_-|WP_015149047.1|DBSCAN-SWA
MPTRDFIHNSVKQALIKEGWQITDDPYIISYGERFLFVDLAATESSMNDAVAGQFIGAQQKNQRIAIEIKAFRNPSAIADLEQAIGQYILYRLLLQEVDPDRIIYLAIPEITYLGIFREPIGELVISQLSLKLIIVNWEEAEVKQWIPARPIETL
>NC_019693|3444735:3506658|3486850_3489562_+|WP_044195128.1|DBSCAN-SWA
MARKRDIFYHSFRFIFKLKFKLMVWAICGLILSLNLPVLSAQIGQGLSGFAENAHPAIAQSIEPESLLERARTAYQNEEFLEAAQLLQQAEAMFGDAVVDRAVSLSYLSLVYQKLGQWPEATEAIATSLSLLENTANVPLSVLAQTLNAQGNLQLAQGQAEAALETWKQAEMAYQKSGDREGVRGSLMNQAKALESMGFSRAACNTVLEVLEVEGLTCESLVQSPDPESTSKKSNLDEFLISLQRQPNSAIKAMALRSLGNLLRSFGYLERSQQILEQSLQVTETLQSPQEISLSLLNLGNTARAQEDFTHALAFYNQAAIAASSPATRLQAYLNQLSLTIEVEQIATASPIITQIQSELDDLPTSAIAVYARINFARSLWELRNQSNRYDLAQIEELLKIAEQQAQELGDDRLRSHALGNRAWLSEQKEDWLQAQQLTTDAIFLAKDAPEIAYQWQWQMARIKQKNQENSSALQFYDAAIASLKLVRKDLTGINPDIQLSFQKQIDPLYREFVDLLLQGENPSTENLEKARQAIADLQLAELENFLRCSLQTETPVELDRLADEHQAAIIYPIILPQRLAVIVKRPGSSDLLYFQTEILRQEVDQKLDNLRKQLERTSISIEAKQLSQEVYDWLIQPIETASNSQINPIKTLVFVLEGRLRNIPMAALSNSNGEYVVQKYAVALNLGLELKDPQPLAQQSLTALLAGITEPLRGMPALEYADRELNLVENSVSSSRQLRNQKFKKETLENQINSRSFAIVHLATHGEFSSQLEKTGIEAWDGRINLDELSTIFTQQTENQPSPIELLVLSACKTAEGDDRAVLGLAGVAVRSGARSTVASLWYIDDETSALLMNRFYYYLNDPRALSKAEALRLAQDDIRKEFINKRAPYYWGSFVLVGNWL
>NC_019693|3444735:3506658|3464196_3464823_-|WP_015149048.1|DBSCAN-SWA
MPSGRTHDEITLWSLPLVAGGTYAQTRSSSLTLIVAGGFLFSGLMFGPDLDIYSQQFQRWGWLRWIWLPYQQSLHHRSFLSHGPLVGTALRILYLGIWIGAIAFGVVLVGDYLGLFTWNPPLASAAIARTVKQHPMEGIALFLGLELGAMSHSLSDWIGSAYKRFKKYGWSAIFNPSKKPRTPAKKRIKRHTSSGTPRPQKASTKRKS
>NC_019693|3444735:3506658|3449681_3451010_+|WP_015149033.1|DBSCAN-SWA
MTSMQIGSENLVTIAQSTAIAARKLGILSTEAKNQAIEAVAQSLQSAASEIVAANAKDCEIAQADGISKPLYNRLKMDRTKLEATIAGVRDVGKLPDPVGEIQLHRELDEGLILKRVSAPLGVVAVIFEARPEAAIQISALAIKSGNGVILKGGKEANHSCAAIVKAIRQGLAQTEVDPDVVQLLTTREETLALLKLDNFVDLIVPRGSNEFVRFVQDNTRIPVLGHAEGICHLYVDASADIEKAVTIAVDSKTQYPAACNAIETLLVHEAVAPEFLPQVAAALQGRQVQLRLDQKSQAILKNTPNLQDWEPATEEDWKTEYTDLILSIKVVDSLEEAIAHINTYGSGHTDAIVTEEQSAANLFLSQVASAGVFHNCSTRFADGFRYGFGAEVGISTQKMPPRGPVGLEGLVTYKYQLVGKGQVVATYSGPEAKSFTHRNLA
>NC_019693|3444735:3506658|3459643_3460795_-|WP_015149042.1|DBSCAN-SWA
MNEANEHSRQPVQAGGKLSVFERYLTLWVFLCIIAGIILGKLFPGVAVALDAMSIYQVSIPIAICLFFMMYPIMVKIDFTQAANAVRAPKPVLLTLVVNWLIKPFTMVAFAQFFLGWLFRPLIVGTEIINNETISIANSYIAGTILLGIAPCTAMVLMWGYLSFSNQGHTLVMVAINSLAMLFLYAPLGRWLLAANDLTVPWQTIVLSVLIYVGLPLAAGMYSRYWIFKNKGRQWFEREFLKYLTPISITALLITLVLLFSFKGDLIVNNPLHILLIAVPLFIQTNFIFLITYVAGLKMNIAYEDAAPAALIGASNHFEVAIATAVMLFGLNSGAALATVVGVLIEVPVMLMLVEVCKKTANWFPREPEKATLRDPRCFPSLR
>NC_019693|3444735:3506658|3489617_3490496_-|WP_015149060.1|DBSCAN-SWA
MSKKIEINNSIQIWVILACLMAALSYWVLPGNGQIPPSFNPLRFIPREVYNEDTSNGSGEGKPGDTEPGGGTRPSNLEGSLCPEEVAKPLKALVPSRIVMEQTESGDRRVEYVEEYTVSSSPTFWFFVPYRAPLQAEFALVNENAEELYSTTITLPENPGIIGIGIPAVATDKLLELGKYYRWQLTIVCYPDRPSLNNLFVQGWVQQVTPSQQISQWQGINRQEMPYETLRQAVAGYATEGIWYDALTLLGDRRLQNPSNSEITGDWQSLLNSVNLGDFADEAIVERYVIEP
>NC_019693|3444735:3506658|3482152_3482461_+|WP_015149057.1|DBSCAN-SWA
MEHRELQDISGHQAEAIPIFFVWGRSASFTRSRWWIKADEPVFNRLFEPEERMIEVKAISFEATETNSSVTSVPQPSSHYVGVLVLGILGIGLALKRQRGTM
>NC_019693|3444735:3506658|3495186_3495510_+|WP_015149064.1|protease|DBSCAN-SWA
MSSASVHRKNWFVAIVRLLFFKNHSETGHHYVTPNPEFLTSVEQEAIVDEAILPRKVGRVYFGGSWWPARCDRAITLSPGETVYVVGRHNITLLVEPESFIKPTFRR
>NC_019693|3444735:3506658|3462501_3463350_-|WP_015149045.1|DBSCAN-SWA
MSNSDFANSTPSDSSALPALEKLIQVVAQLRSPEGGCPWDLAQTPESLIPYIIEEAYEVVDAIKSGDQQAIAEELGDLLLQVVLQSQIASEVNQFSLTEVAEGIAEKLIRRHPHVFGNVEVSSVEEVRTNWEQIKAEEKGETGTEVKPLSDKLGRYARTLPPLMAGMKISQKAAAVGFEWDNVEGVWEKFEEELGEFRYAIAHEDKARQQAELGDLLFVVINLARWYDLDPSDGLAETNHRFVQRFSKLEAACDRPLSEYSVEELEAIWQRIKALLAKQRQA
>NC_019693|3444735:3506658|3499059_3499296_-|WP_156823840.1|DBSCAN-SWA
MQHLPFELPHPPAVEHPTRSAFVPVLVGLCVWRGGSTLSSNSYRIHSTSDRLVNNCRWRQLSDIAPVLLQGSILSGTH
>NC_019693|3444735:3506658|3466657_3467002_+|WP_044197130.1|DBSCAN-SWA
MWEKSGNYRVQNLDPTVSEVEKTFLELAEQWRRETRGISSTNKASMHPLYQQIIGMGKAVIPLLLRELERNSGQWFWAIKAISQEDPVPPEKRGQTQEMIRYWLEWGKQKGYRW
>NC_019693|3444735:3506658|3457718_3458858_-|WP_015149040.1|DBSCAN-SWA
MMRLLNPIKPARMVFSLSVVALTLGIGACQGPTENNTTAPEGNVAPEGTGKLALSEPVNLTGAGASFPAPIYQRWFQEFNQDNPQVRTNYQSVGSGAGIRQFSSGTVDFGASDVAMKDEEIQAMNQEILMLPMTAGGIVLAYNLPGVETGLRLPREVYVDMLMGEITQWNDPRIAAANPGVNLPDQAIAVVYRSDGSGTTGVLTKHLSAISEKWKESIGEGTTVEWPTGIGGKGNEGVTAGIQQTVGAIGYVEYGYAKNNNIPMAALENKSGNFVLPSDEAASKTLAAVELPDNLRAFISDPEGAESYPIVSYTWLLAYQEYSDPQKAQALSAVIEYGLNEGQLLAPELGYVPLPLNVRQKVAEKANVISPEYDIEVTE
>NC_019693|3444735:3506658|3505461_3506658_+|WP_156824047.1|transposase|DBSCAN-SWA
MSQLLDLAGVWVKDYKIHKEIGLVLQIESLQKLAVCPLCGHQSNKLHQNHWYLVKDLPFSQHPTYLRVNRRQFKCQTCQKPFSESLDYVNPKRNYTKRLTLKIVEEVLESNIQSVARRYQVTEEEIQTMLSDVGSELLQEKPAPFRRLGIDEISQRKGQGNYCAVLVDIDAGKPVGIVDSRRKEELLKVLQGWGSEILNFIEEVSIDLWMPYKTLVEELLPHAQIVADRFHLMKGLNEELDSQRKFEKYLINSQENYPEKSDLISAINKSKYPLVKNEKDLTEKQNKKLKEVKLKFPQLAIMHDLKEEFRDIFESKQQGTEGLVKLVDWLFKAQQSFPTFTKTVIRWFPEIVNYFENRTSNGVVEGINNKLKVIKKSAYGLPKFENFRLRSLLNWMFT
>NC_019693|3444735:3506658|3455584_3456490_-|WP_156823839.1|DBSCAN-SWA
MSQPFSSPRDDFYNENPHGEQLMRNYKTPRSLFVWVMTVLSGACLVLTLVPLFAVMIYVTIKGFNRLNLDLFTELPPAAGMEGGGIANAIAGTLIMVGIAAAISVPIGVFGAVYLSEFSSVRVARWIRFATNVLSGVPSIIVGIFAYGIIVLATKQFSAFAGGVALSVLMLPIVVRTTDEALQIVPPDVRWASVGVGASNHQTVLRVVLPAALPAIITGLTLAIARAAGETAPLIFTALFTFFWPQGLFEPAPSLAVLVYNFASVPYASQQELAWAASLILVLLVLLTSILARWATRKSIY
>NC_019693|3444735:3506658|3499217_3499511_-|WP_015149067.1|DBSCAN-SWA
MSNSRYSQDWQAIALAIKEQAGWRCSKCGLQCLRPGDPKNHLSKSERGKLMLNVHHHNRIPEDNRPENLIALCSTCHLSYHTRQQSNIPPGQLSFQF
>NC_019693|3444735:3506658|3504753_3505227_-|WP_044195134.1|DBSCAN-SWA
MDVYMGVTRPSQPVTPSEVGGDKAQGKSEFNPRKNPVAQIYFPTNDSKLDSQDIGILFLLANALEGAEFVSLNFYGYADKREAVDYNLQLTDLRTASVSSRLLTLLDKQNVNDYEALDVPLSEIERPQNGTTAEELKPFRRVDIEIQQLKSHIPQVK
>NC_019693|3444735:3506658|3444735_3446331_+|WP_015149030.1|tRNA|DBSCAN-SWA
MFWADKIAESAQGEQIVNDSKTPSGRVHVGSLRGVIIHDVIYRALKHAGKPVKFMYGVDDYDALDTVPGYLDREKFAPYLGYPLCNVPSPDDKATDYAKYFMGEFLEVFDYLGVKPEIYYLRDLYRTGQLNPYIDTFLQNSHLVREAYKEVSKADRPSNWYPFQVICENCGKIATTVVTDYNGKEVFYTCEPNATNYVNGCGHSGWVSPFDGNGKLPWKVEWVAKWQLVGVTIELAGKDHSQKGGSRDVANAICRKVLKKQPPFHSPYEFILVNGTKMSSSKGVGSAAKEIAELLPPELLRFLMLRTQPKSVINFAPNYETTTRLFRDYDTLIEKYQGVTPEGGEDPKQDKELQPLFYSQLTDEVKTYQPFDFSTLISLLQVPHLDIKEEIQKRCEHPLTDADWKVLHQRIESAQKWLDDYADEEEKLVLYFDTIPEQVQELTEEQVTYLGELAKNLEAAESWDGETLQTIIFSTSKGLEMKPGNAFPAVYLSFMGKSRGPKAGNLLSYLDKSFVLERIRGAVALKQGAAV
>NC_019693|3444735:3506658|3466995_3467478_+|WP_044195124.1|DBSCAN-SWA
MVENEPIGNSAWRTQVRGWIEADYPNLLRTEYRLTSPDTIDYNCIAWALEDTSKWWWPDAMEQQYWPPHVKREESLEAFIQVFASFGYEVCEMASLEVGFQKVALYADSKGIPTHAARQLDAGKWTSKLGQDEDIEHHELEGLVGEKYGQVAVILKQFIP
>NC_019693|3444735:3506658|3481359_3481995_+|WP_015149056.1|DBSCAN-SWA
MTYFWNLENREPQDLYGHQIESLSGGFLSIKSTTNSNAEAISLPFIWGRGGSFTRSHRWIDPDENFTNTFGQRPDDVYWWQLRSLASSSNNTNGGINLTSVNHQEVSSEDNIFLVLAQNDILDPFINTANPIRFRSENPLTDETIFNRLFTQDYQVVEVTEISFEETETNSPVTSVPEPSSYVGVLVLGILGVGLALKRQLGTMRSRSSSV
>NC_019693|3444735:3506658|3500730_3500901_-|WP_156823841.1|DBSCAN-SWA
MLRVDSIGQSECRSWDAIAYARAALTARRIRSIVQIGFGSGVAIAYKIVLLCGTAD
>NC_019693|3444735:3506658|3467778_3468033_+|WP_015149052.1|DBSCAN-SWA
MYAAPQLQDDSAIASPQLLDPTLLKAARLLYRAYKDVHPDGIQRPLGVAIDRFTYRGQLIFTQKPALLLTECFVPFDQLEAGLY
>NC_019693|3444735:3506658|3501471_3502602_+|WP_015149069.1|transposase|DBSCAN-SWA
MDSILTPAIALVNVLLNIMPSIYQRDSIQALFGLFLEGNGYPLPQHCKNKSASALSRFLNHYNWSTRAVIKAVRADIVAQIKTLAPTGRRPILYLILDMTTLEKVGQFTGLNNLIRVYNGKRGLHLLVLYILLGERRLPWGFKVYRGKDETPPVQLAIRLLNTLPQSLKTRFEIRILADTAFGSIDFLKWINQHKNYHGIVGIRKDRRLSDGIRVSEVSKRGQQVVLHGIDFPVTLSWYWVKKENGQKEKRFVISTKPLSAVYITMLGRRRWNIEGFFKVAKHRFGLHRFGQGTLKGVYRWIILSMIAYLLAHYACLWSGSTTRTDWGEASKLAKETLFPRLVLRMLLIEIKEKAWIARQQGLDIRITTTRPCLAN
>NC_019693|3444735:3506658|3468212_3469037_+|WP_015149053.1|DBSCAN-SWA
MDVIVAIAAVAVALTLGASIGSFINVVAYRIPAGLSLLWPPSRCPHCLHKLGKTENVPVFGWLRLRGRCAHCKSPISVRYPIIEALTAVIFMVVALFTWENPMQMIGYWVFFSWLLALSIIDLDTMTLPNPLTQSGLVVGLGFQMVTGWAIASNLQGIPHQLMVGVIGAVLGIWLLDSISFLGSIAFGKTAMGAGDAKLAAMMGAWLGWKLMLLGGFIACAAGAFIGGGAVALGWLERSKPMPFGPFLALGAAIAALWGDTILSAYLDLFFPLQ
>NC_019693|3444735:3506658|3469090_3470218_-|WP_015149054.1|DBSCAN-SWA
MSTYQYYEFQALDRPLTEKEQDYIRTLSSRVQLNRTQAIFLYHYGDFRGKPEQVLEKCFDIMLYTANWGSRQLMFRLPKSLINPVELEPYQVPDGIEISTTEQSVIIDIKILDEDLNGWTEGEGLLPRMLSLRDDLLQGDYRVLYLGWLQAAQLCYDFEPDTCIEPPIPANLHNLSKPLQAFVDFIELNQDLIDAAAQLSPLAETKSDSIKELQQRIPQLSEEERNKFLARLLQGELNLNLELSQRLRSLSKKPTPQTLSDSPGRTLSELLTLCVQSEKLRKQKEQQTAKQEKIQKIQELAPRESYLWEQVFHEIGCKQVKAYDRAIVHLLNLQDIAEYQGKLPEFQARVRKIQQDYSNLRGVMSRLRDFKLWQD
>NC_019693|3444735:3506658|3454414_3455239_-|WP_015149037.1|DBSCAN-SWA
MSFDRQTANHHQTEPQTEAILRTENLNVYYGDTLALKGVNLEIPKKQITGFIGPSGCGKSTLIRCFNRLNDLISGFHIKGKCSYYNQDLYDKKIDPVEVRRRIGMVFQKPNPFPKSIYDNIAYGARVNRFKGNLDELVETSLRRAALWDEVKDKLKSNGLSLSGGQQQRLCIARAIAINPEIVLMDEPCASLDPISTMKVEELMQELKENYTIVIVTHNMQQASRSCDYTAFFNAQATEDGKRFGYLVEYDKTENIFQNPKQEATLEYVSGRFG
>NC_019693|3444735:3506658|3462039_3462369_-|WP_015149044.1|DBSCAN-SWA
MVNTTENAPAEIAAGFHAFSDPLRISILELLRDRELCVCELCEILKVSQSKLSFHLKTLKEAALVRARQEGRWIYYSLNIPQFAVLEQYLAEYRRFSPILPARSCNGDS
>NC_019693|3444735:3506658|3460919_3461948_-|WP_015149043.1|DBSCAN-SWA
MNATAQQFLSGVKRWAAIAGVAALMASCQNSNSQVLQPIIMDGSSTVYPITQAIADSYRETHPNPAEVTVEFSGTGGGFRKFCAGETTINNASRPITLEEMAACRESGVPYIELPIAFDAITLVVHPENTWVDRLTVEELKKIWEPGAEGRISNWNQVRSSWPSRPLTLFGPGRDSGTFDYFTEAIVGESDASRNDYTASEDDDALVEGVRRDPNALGYFGYAYYESHREGLKAVALDHGTGPIMPSRETVESAQYQPLSRPLFIYVNADAAQKNPALQAFVEFYLEKAPELVSNVGYIPLPEEGYRLAYIHFHRHKVGTVFDGKAAFDLTIGELLTKQAKF
>NC_019693|3444735:3506658|3503106_3504729_-|WP_015146995.1|transposase|DBSCAN-SWA
MTDIASDIIVQDIDHCGIVSGIIDEIGLVELINRELEPHPLTLVSPGIVVKAMILNGLGLVSAPLYLFPQFFVGKATEHLLGEGITPEMLNDDRLGRVLDELYKVGITQLFVKVALAAAKKFRVNTRSKHLDSTSFHVHGQYLREPNLTGEPVPIEITYGYSRDHRPDLKQFIVDLICSSDGDIPLYLRVASGNESDSAIFAKLMKEFRENWDMDGLFVADAALYNQENLRQINHLKWVSRVPASLKAAKELLSEPAESDLKKCQLDGYRIKSCEITYEDIKQRWLLVESEKRKESDLKQLKKKIKNLAEKGRAELKKLSQQKFACQPDAEQAVEQFNKKLRYHTITGFEILTVPYYTQPGRPPKGAKPAGYCYQIQGTLSENEAAIEQEKIRAGRFILATNVLDVNELSDEQILEEYKNQQSTERGFRFLKDPMFFTDSVFLKNSERIEALAMVMGLCLLVYSLGQRALREALAQAKKSIKNQVGKPTTTPTLRWVFQCFQSIHLLTVDGVKKITYLTDERRWILQFLGASCQKYYLLT
>NC_019693|3444735:3506658|3453119_3454124_+|WP_015149036.1|DBSCAN-SWA
MTYRILSIDGGGIRGVLAARMLQRIEERLELPLRDHFDLIAGTSTGSMVGAAIAMGIPCEKIVQLYRKKSKKVFPYRSRWTLKRLPLLLQHGPSAPKFSEAGLIRMLKDLLGEKRLSDINPAKLLITSYDTIGRSPIIFKSWKEKFANVPVWEACLCSASAPTFFPAHRLVIDGEVMSAIDGGLAANNPTACAVAEAIRLGHRLEDLEVISIGTGAATRVIPWEQARSWGTLQWIWGGRVVKVMTDAPCEVYHYITDYVIGDKSRYARLQFPLDRRLIHKPLSDDMDDASNENINNLVEAADAYMNLVEVVECLDMCLRKAEPPQVHVQERYQR
>NC_019693|3444735:3506658|3499875_3500580_+|WP_015149068.1|DBSCAN-SWA
MLEKINKSINLFMQNWMLFSMIVLTVWLPASILLVYLRWYVFPEMTGGDELQILAKEYRVQGLIETIFGPFCTGALIYALAQIKQDAMPTYGECMAHAARRSFKLVGTRIGTGLIVVGGFLLLIVPGIILALRYALTDTVVTLDRIDGANARKYSAQLTEGKRGELLGTMIISFSLVLLASVFVSLLFSMFISEAEGGIFVLDVLYECLIQLAITVITTTILFLFYWESKEQES
>NC_019693|3444735:3506658|3451159_3452194_+|WP_015149034.1|DBSCAN-SWA
MKVFTKAALIRVAVLSLIVIFGLTLGWNTVINMPGKSYAGDLPPLTEREQALQVELRQSIENIAGEDIGEHNYFYYNQLEAVADWIESEFTAVGYEVKRQTYEVNGQQFHNLEVEKIGTKKPEEIIVIGAHYDSVVGSQGANDNGSGTAAVLAIAREFADKSTARTLRFVGFTNEEPPFFWTENMGSFVYAKRCRDRQENIVGMLSLETMGYYSDQPGSQQYPLGLLNLVYPITGNFITFVSNLPSGNFLREVIGSFRSHTQFPSEGAAMPGATPGAGWSDHWSFWQFDYPALMVTDTAPFRYPFYHTMQDTPDQVNYDRLARVVSGLERVIEELAQGRIAASI
>NC_019693|3444735:3506658|3459191_3459605_-|WP_015149041.1|DBSCAN-SWA
MTKKVMFVCKRNSCRSQMAEGFAKTLGEGKIEVTSSGLESSRVHPTAVEVMEEIGVDITNQTSDPLSDFQAEDYDVVISLCGCGVNLPEAWVLREVFEDWELEDPDGKPLETFRAVRDEIKARVSKLIEAIATEVPA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015149030.1|3444735_3446331_+|tRNA	lysine--tRNA ligase	NA	NA	NA	NA
WP_015149031.1|3446530_3447487_-	3'(2'),5'-bisphosphate nucleotidase	NA	NA	NA	NA
WP_015149032.1|3447569_3449285_-|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_015149033.1|3449681_3451010_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	6.8e-87	44.8
WP_015149034.1|3451159_3452194_+	M28 family peptidase	NA	NA	NA	NA
WP_015149035.1|3452282_3452738_-	hypothetical protein	NA	NA	NA	NA
WP_015149036.1|3453119_3454124_+	patatin-like phospholipase family protein	A0A1B2LRS3	Wolbachia_phage	1.1e-33	34.3
WP_015149037.1|3454414_3455239_-	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.0e-17	34.4
WP_156823839.1|3455584_3456490_-	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_156824060.1|3456636_3457578_-	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_015149040.1|3457718_3458858_-	phosphate ABC transporter substrate-binding protein PstS	M4SNR3	Cyanophage	3.8e-70	48.9
WP_015149041.1|3459191_3459605_-	arsenate reductase, glutathione/glutaredoxin type	A0A2H4PQT9	Staphylococcus_phage	1.4e-19	43.7
WP_015149042.1|3459643_3460795_-	ACR3 family arsenite efflux transporter	NA	NA	NA	NA
WP_015149043.1|3460919_3461948_-	PstS family phosphate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_015149044.1|3462039_3462369_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015149045.1|3462501_3463350_-	nucleoside triphosphate pyrophosphohydrolase	NA	NA	NA	NA
WP_015149046.1|3463406_3463730_-	XisI protein	NA	NA	NA	NA
WP_015149047.1|3463696_3464164_-	XisH protein	NA	NA	NA	NA
WP_015149048.1|3464196_3464823_-	metal-binding protein	NA	NA	NA	NA
WP_015149049.1|3465040_3465772_+	JAB domain-containing protein	NA	NA	NA	NA
WP_044197130.1|3466657_3467002_+	hypothetical protein	NA	NA	NA	NA
WP_044195124.1|3466995_3467478_+	hypothetical protein	NA	NA	NA	NA
WP_015149052.1|3467778_3468033_+	hypothetical protein	NA	NA	NA	NA
WP_015149053.1|3468212_3469037_+	prepilin peptidase	NA	NA	NA	NA
WP_015149054.1|3469090_3470218_-	hypothetical protein	NA	NA	NA	NA
WP_015149055.1|3472580_3481184_+	S8 family serine peptidase	A0A2P1ELB3	Moumouvirus	7.9e-19	24.4
WP_015149056.1|3481359_3481995_+	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
WP_015149057.1|3482152_3482461_+	hypothetical protein	NA	NA	NA	NA
WP_015149058.1|3482582_3486905_+	filamentous hemagglutinin N-terminal domain-containing protein	NA	NA	NA	NA
WP_044195128.1|3486850_3489562_+	CHAT domain-containing protein	NA	NA	NA	NA
WP_015149060.1|3489617_3490496_-	DUF928 domain-containing protein	NA	NA	NA	NA
WP_015149061.1|3490520_3493037_-	CHASE2 domain-containing protein	NA	NA	NA	NA
WP_052315743.1|3493070_3493976_-	DUF1822 family protein	NA	NA	NA	NA
WP_015149063.1|3494000_3494612_-	hypothetical protein	NA	NA	NA	NA
WP_015149064.1|3495186_3495510_+|protease	membrane protease regulatory membrane protein	NA	NA	NA	NA
WP_015149066.1|3497504_3498956_-|transposase	IS66 family transposase	NA	NA	NA	NA
WP_156823840.1|3499059_3499296_-	hypothetical protein	NA	NA	NA	NA
WP_015149067.1|3499217_3499511_-	HNH endonuclease	NA	NA	NA	NA
WP_015149068.1|3499875_3500580_+	hypothetical protein	NA	NA	NA	NA
WP_156823841.1|3500730_3500901_-	hypothetical protein	NA	NA	NA	NA
WP_015149069.1|3501471_3502602_+|transposase	IS701 family transposase	NA	NA	NA	NA
WP_015146995.1|3503106_3504729_-|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_044195134.1|3504753_3505227_-	hypothetical protein	NA	NA	NA	NA
WP_156824047.1|3505461_3506658_+|transposase	ISL3 family transposase	A0A2D1GQC1	Lysinibacillus_phage	1.2e-26	27.8

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NC_019693|6607210:6661213|DBSCAN-SWA
CTCAACCCGACTGGAACTGCGCCTCTAGGGTTTTATCAATGCGATCGCGAGTTTCCTCTAGGTGGGCTTTACTGGCGGTATCCAGATGCCGTCCTCGCCGTTTTAGGGTATTGTCCACTTCCCCTTGGAGTTGCCGTAAGTTATACCGGGCGAGAGTTCGGGCTTCATCAGGAACGCTTGTACTCCTTAAAACCATCCCGATTAACATCCCTAAATGTTCTCGTTGGAGACTCCGGCGAACACTGGAAATCACGTTTAGGTCATCGGGGGAATCGATGACCTCGGTCCAAATTCCTCCTTCTAGGGTGTCAAATAGTTCCTGCATGGTCAAGGCTTGACCCGGTTCCGTTTTTAATTCTAAATCCTGTAAGCGGATTAGCCTGGGATAGGAGAACAACTCGCGCAGAACAACCCGTTGCAGTAAATTAATCCGTTGATGAATGGGATAATCCAAGGGATAAACCACGGGAACTGCACCCCAGTGATACCAGCGATCGGGGGCTAATTTATTCAGAAGTTGCGGCGGAAATCGTAATGCCGTTTCATCGAAAATGTACTTTTGCAGCAATGCCAAACTCTGACGCTGTTTCTCCACGGACACGGGTTCAAAGGGTAAGCGTCCGTTGGCGTCAGCATGATTGCGATTAAACCATTGACCTCCTATATAAAGAGTGGCATTCATCGCCTGTCTGAAATAATAGGAAAACACGGTATCAAACATCTGACGGACTTCGGTGAAACTTTCCCCACTGACGGGATAGCGTGTATCCAGGCGTTCCCACATTTCCCGGGCATTTTCCAACTGCCACTCGGAGTATTGCAACATATCTCCGCTGAGGTCAAACATATTCGCCGCTGGGTTGAGAATATCCATCGAATCCTCATCAGGGGCGTATGCTAAATCAGGGTTAGTGCTACTTTCAGCGGCTATTCGTTGCAATTCCCGCTGTTCTTGTTGAGGCAGCATTCCAGGCAGGGGTTTATACCCGTATTCGATCGCCCATTCATCATAAGGGCCGACTAACATTGGGAAAAAGTCACCCTGTTTCTGGTCGCTGGGTGCCAAGTTCACAGGTACATAGTCCATAACGGAGGCCACCATACCTTCTGTGCGAGTAATTGCTGTATTATGCAACTCCTCCGGTGATAACATGGTACTGCCGTGGAAGTTATGGCGCAGTCCCAAGGTATGACCGACTTCGTGGGCAGTGAGGAATGTTAGATACTGATTGATATAGTTTGTCATTTCCTCCCCACTGGGAAAGGCATTATGAAGCATGGACAAACCCATTGCCCCGATCGCCAACTGTTGGGGCGCTTCCATGCCATAGCAGAGGTCGTATCTTTCCATCATCTTGCGGACGAAGCTGTGCACCTGGGGCGGTTGTTGGACTGAGGGACCTGAATTCCCCATCATCCCTTCACTGTTACCCATGCCGGAGTTGCTACTCATTCCGGGGAAGCAGGGAGTCCCCTGTAACATTTTGCCCAAGAAGGTCATTTCTGAGGCATTGGGTTGTTGTTGAACCAGGGTGCGATATTCATTTTTGATACTTCGCACGATATTCCCATCAATGAGAATATCCGCATCTAAAATTTCCCCGGTGAGGGGGTTGACGCGAGAGGGTCCGACTCCGGCAAACCAGGATTCAAAGGAACTGGACCAGCGAATAGTGTTGTAGCGCACATCTGACGGATCCCACTCCGCATTATCGGGCATCTGTCGGGCTTCGATCGCATTACTAAACCCAGCTTTCTCGAATGCCTGATTCCAGACTTCGATGCCTTCGCGCAGGGCATCCCGATATTCTACCGGAACGTTGTTTTCAATCCAGAAAACAATCGGCTGTTTCGGGGGAGAAAGTGGGGCATCGGGGTTTTCTTTTTCCAAATGCCAGCGGTTAATATAACGCTGGAAGGGTTCTCTACTGCGATCGTTGGACAAATCTTGATAGGCGGTGATAAAATACCCAACTCGGTTATCCGCTAATCGGGGACGAAAGCCATTGTTAACCGGCAGTGCGGAGAGGCTATAATTCACGTTTAGGGAAAACCCCCGACTATCGGGTAAACTCTGGACAGTGGAGAATAAATCATCCCCACCACTGAATCCATAGACGGACTCAATTTCCACATTAGAGGGGAAGGTTTGAACTCGCCCAAAATAGGATTTGTCGCTATCTCTGGAATAGGCTGTCCCTAATAACCAAGGTAAAATTGAGGTTAATCCGGTGATATCTTGACGATCAATCAGGAGTTTATTGAGGTCAATCAGCAGGCTTTCCCGGTCGGGATGAATGCTTTCGATGGGTAAAGAAGCTAGAACGGAATCACTAAAAGAGCGGTTTAGCGATCGCTCAACCGGGTCTCCAGGACTGGCCCGAAAATAAACATTCCTCACCCCAAAATGGATGTTTTTATTCACCCGCTTAAAGAAAAAGAGAAAATCCTGGAGGGGCATTCCCCTAAACAATCCCCCTTCTCCAATGCCGGATGCTAGGGTCATCACGGCTAAGAAGTTTGTGTCGAGTTGTTCCGGCTGAATCTCTAGGTAAACTTTGCCGGTTTTCTTATTATGGTAAAGGGTGAAGAGTCCTGGGAGGTTTTCAGCATCTTTCACCACTTCATCAAATTTTTGCAGGGAATCGCTGTCGTCTTCCTCACTCTCCTCGCTGTTTTCGGCGTCCTCGTTGTCACCGTTTTTATCTTCCCACTCATCGGGTGTGGGAACGGGTATGTTTTGGCTGTAATATCTCGGTTCCGGCATTTGGCTATTTGCCTGACCCGAAAACAGTCCGAAGGTTACCGGCAAGATGAAAAAAGCCAAAAACAAAATCAATAATCGCTTGGCTTTTGACATTTTATGCTTCCCGTTTGACTGGAAGTCCAGGGAAAAAAATGTCTTGAGACTCTGGCTAATTTTCACGAAGAACCGCTTTAGGAAATTCCTCTGGGACGCGAATTTTCTCATCAGACGATGCATTAATATTTAGGGTGTGTGTGTTGAGTGGCGACTACATTCACAGCGGGAATGGTTGACCAGTGGAATGCTACTCAGGACAATTGTGCATAAACTGTTATGTTCCGGGCTAACATGAACTCCCTTCTCTTTAATTGACATCAGCACCAAGAGTGCCAATCAATACTGACGGATCGATATCGATGGGCTGGTATGTTCCAAAGTAAGTGGTGCTTCATTATTCTAGAGTAACGGTTTCGCCTCAAAATGGCGAGAGATTGAGGCCACGAACACTTCTTTCAACGCTCATGGCGACTGCCCTTCCCATTGCCCTCTGCCACCCCGACGATTCCCGGGGAGAGGACTGCCATCGCCACCCCAGATCCCAACTGCTGCATCCGTTTTCCTTCTTCCTTCCGCAAAATCAGGGTCTTCTATCCGGGATGAGTTTCATTCGGGCAAACAACCGAGGGGCAATCTTCCCTGGAAAAGCCCCATTCCATAATTATCCAACTGCTGCAACATGAGCAACATCCCCCTGAACTGGACTAAATTTCTCTCCCTGTATCACCACCGGAAGCACCCCTAATTTTTATCTCGCAAAAACCCCAGGCTTTCTAACTCATTCAACCTGCTGCATTATGATTTTAAGGTGAGATTTTAGCCGTGAATTTGCTGCCTATAATCTTATGATTATACCCGATTTGACGGTTTTTGCTGTCAGTTTTATTGTTAAGAATTTTTAAAGCCCAGGAAGGTACAGCCTCATCATAACGGTAAAAAGAGCCACAGATTTAGGATGACTATCCGGGCTGACATCAGACTGTTCCCCTTAAATTTGAAGAGAATACCCCAGAATCCTGGCAAGTTTAGGTTTTGGACTAATAGCCGGATTCCATCCCCTCCAGAACGACTTGTGGTCCTCTCCCCTGGATCTTGGGAAGAGGACCGGAAGTAGCCCTAGTCTAAAGGATGAATTACTCTATCCGTTCTATCGGGGGCGGAGTCTGAGAATCCCTCCCCAGGCCCTCATTGCGATCGCTGGGCATAGGCGGTGCAGAAGTGGCCGGGAGGTCGGTTGGGGTCGCGGTGGGTTCCGTGGGGGAGACGGGCGGATTTACCGATTCGGTGGGGGTTTCTTGGGGGAAGGGCGTAGGAGTAGAACTGCGATCGCCCGCCACCGGACTCGGTTCCCGGACTTGCACCGGAGGCGGATTCAGAATGGTTTCCCATGCCTCAACTTCTTGCCGTGCCTGATTATACAGATTGGAATAAAATGGAATCATCCGAGCCAGTTCGATCGCCTGGGGAAGATTCTCCAAAGACCGTTGTTGGGCCAAGGCCAAAATCCGTTGACTCCAGTCTTGAATTGCTGCATCCGCGCTAAAGCGTAAATTAGACTTAGAAGAGACTTGATTGGCCAAATCCATTGCCTGAATCAACCGTTCGGGGCTTTGAGCAACATCTCCAAGCTGATAGGCGCGGTCCAGGAGTTGGCGATCGCGACCTTCCTGCTGCCAGGTTTGAATCGCAGACTGGGCCTCACTGTACAGCAACCGCCCGGGACGAATGCCTTGGGCGGTGGCGATCGCCCCAGTGATATTTCCCCATTGCGCCAAATTCCAGGCGCGGTCTAAGATAGGCTGGTCTTCAAGTCGTTGAATTTCCTGATTCCACCCTTGAATTTTGTCCTGGGCCTCGGTGTACAAAGCCCGCCCTGAACCGACATTTCTAGCCGTATCGATCGCCGCTTGCAACGAAGCGCGATCGCGGTAACTAGCCAGTTGTTCAGCCTGTCGCAGATAGGGCCGGTCTTCGGTCTCCTCAATCTGACTTTGCCAATCATTAATTTCTTCCTGCGCTCGATCCCAGACCAGATTGGTGCGACTGACCAGTTGAGCTTGGGCGATCGCCGAGCGCAAATTGTTCACATTCCCCGCCATCGCCAGATTCCGGGCCTGTTCTAGGTAGGCCACATCTTTGATGCTATCCTGCCACTGAGAGATTAATCGTTTGGCTTCCAGGTGCCCAGGGCGATCGGGGCCAATCACTTGGGCTTTGGCGATCGCATCTTCCAAAGAACGGACCGTTACCCGAGTAGCAATGGATCGGGCCCGAGTCAGTTCGATGAAATCCTCTGCCTCTTTTTTAATCGAACTATTACCCGGAACTTGACGAGCAATGTAAATTGCATCTTCCCACTTCTGGTCATCCCCATTTTTGCGGGCTAATGCCAGGATTTGCTTGGAAAAGTCAGTGGCTAAAGACCGAGATTTTTTATATAACTTGCTCTGAGGTTCAATTTTATCGACCAGGGCGATCGCTTCGGTGATATTTTTGAGTTCTCCTTGTTCCGCTAAACTGCGGGCTTTTGCCAAGGTTTGACCGTCTTGCTGAGTCACCCGAATCAGTTCATTGAGGCTATCATAACGAACTGTTTCCCAGTAAGTATTTTCCACGGAAAGCAGTTGTCGCATATAGCCCAGAGCTTGGTTCCAGTTTTCCTTTTCTAACTCTGACTCAGCATTTTTATAAAGCTTTTCCGCCTCATTCCAGATGGACTGCCAGCGAGTAATGCGCTCTTGGACTAAACCGGCAGCGGTCGTATTGCTGGGAATCTGACGGGCGGCGGCGATCGCTTGGGTGATCTGGCCTTCCTGAAATATTTTCTCAGCCAAGTCCAGCAGTTGTCCTGCCCATTTTTCAATCTGACGATTGATTTCCGGACGCAGGGGGTGGTCTTCAGGAAGTTGATGCACCTGAGCGATCGCCCGCAACAACCCCTCGACCGTTTGATCCCTCGCCGCTTGTTGAGCACAGTACAAATGCTCCGAAGCCGAAGTCCAGGTACTCTCTTCACAAGTGGGCGTCGCCGGAAGGCGCAATAATATCAGTAATGCTGTTCCCCCCAGTCCTCCTGTCAACAGAAAGGTGACCAGCGCCCAGAGTTGCCAATTTGTTAACCATTTCAGCCACCCATGCAGACGGCGATTGGAGGACCTACTATCTCGAATCTGTGGATTTAACATGAGGTCAGCCTTCTTACTCTGTCCAAAGTGCTTCTGATTCCCAGACCCCGGGCGATCGGTTGCTCCTCCTGTGGAAAATACATCCGATCTCGAAGAGGGCAGGTGCAGACCCGAACCCTGCTGCGAACCCGCCCCAGCAGCACTCCTGCCGAACCCAGACAGGGACGATGCAGGCATTTTCGCCGACGAGTCCGGTTGTCCCGACTCCGACGGCTGGGCGTTAGGCCACTGCTCTGGAAATTTGCGATCTTTAGTCATAGCCCACCCGAAAACACTCTTGCATCAGTCTTAACTTGGCTGTTTTAGAAAGACAGGTTTTACGATTCGGCCACAGTTCCACAACCTAAGTATTAGGTTCGATAAAAGCCGGTTATATGTTCCTCAATCTAGCACCAAGAATTGTTTAGGTTAAGAGTGCTAGAGCTTTTTTGGCAACGCCGTTCGCTTATTGACCGTTTCCTTCTAGGCGGATCTACATCTGCACCCACCGCCTTTCCGGTTTTCTCTATCCTTCTTGTCCCTTCTTGTCCTTGATCATCTGTAGATTAGGAGCATCCAGATACTTTAACGCAATCGATCAAATCCTGGAAAACAGCTTATTCCAAGTTTTGAGAGTTAGCGCATCCAACAAGCCAGGACAATCAATTCTACCGTTGAGTGGTCAATCCGATTGATTGCTTCTTATCTTCTCATGTTATTTTCAGTTGCGATCCCCACTTTTAAAAAAACTTCTACCTAGGACTGCACGCCCTAGCGGTTCAAAACCCAGTTTTTGTACAAAATTTACACCAATTAGCAGCAAATCTGGCCTGTAAATCCGGTTTCTCACGGTTACTGGACCCCCATAGTCGCCATGAGTTTGATAGATAGGGGTCCAGTAATAGTTAGGCGATCGCCTCCATCAAGACTCCGCTTGCAAAGTCCCAATCAGTTCCGTGAGTTGATCGCGACTGGCGGTGTAAACTTCCCCACAGAAGTGACAAATCGCCTCAGCACCATCGTCTTTCTCAATCATGTCCAGCAGTTCTTCTTCCCCCAGCAACTTCAACGCCCCTAACATCCGTTGATGAGAGCATCCGCAGTGGAAGCGCACCAGTTGTCTCTCCGGTAAAATATTCAATCCCATATCTCCAAGCAGTTGCTCGAAAATATCCGGCAGAGTCTTACCCGCTTGTAATAACGGTGTAAAACCCGACAAACTGGCAACCCGCGATTCCAACAACGCCACAAGTTCATCATCGGTTGCTGCTTTCGGCATCACCTGCAACAAAATTCCCCCGGATGCTTGCACCCCTGCTGCCTCTACAAATACCCCCACCACTAGGGCCGAAGGCGTCTGCTCTGAAGTCACCAGATAATGAGCAATATCATCCCCGATTTCACCAGAAACCAGTTCTACGGTACTGGAATAGGGGTAACCATATCCCACATCTCGGACGATGTAGAGATAGCCATCATTCCCGACAGCCCCCCCCACATCCAGTTTTCCGATCGCATTCGGTGGCAATTCTATCTCCGGATTCTCCACATACCCGCGCACGGTTCCATCTAATCCCGCATCCACGAGAATGCCGCCTAATGGTCCATTGCCTTTAACCCGAATATTCACTCGCGATCCCGGTCGCTTCATACTGGAAGCCAGGAGTAACCCCGACGATAGCGTCCGTCCTAGGGCTGCTGTTGCCACATAGGAGAGACCATGCCGCTGACGCGCCTCTTCCGTCAACCGCGTCGTAATTACCCCAACTGCTCTAATCCCTCCATCGGCTGCTGTTGCTCTAATCAGTTGATCTACCATGCCAAAACCTTACAATTCTTAACAAGTCATCTAAACTTTATTGTAAAAGGGAGATGGGGGGGATGGGGGAGATAGGGGGATGGGGGAGATGGGGGAGATAGGGGGCTTACAAGAGTAAGTTTTTTAGTTCCGGTCCCCTCCCCTTGGCAAGGTCCGGGTTAGGGTGGGGTCCTCATTGATGCGCGATTCCCTACGGGAGAGCTTCCGCTTACCGCAAGTCAAGAGGAATGAGTGGGTGGAGACTAATAGTACAGGCGCGATCAGTGAAGAAAGAGGTTTGAACAGTCTCTATACAGGTGCTTAAATTGTTAAGAGTGACGCGCAAGTGGCGATCAACCAAGAACCCCACCCTAACCCTCCCCTTGCCAAGGGGAGGGGACCGGAAGTGCTCTTAAGCGTTAAAAAACTACTTTTGTAAGCCCCCCATCTCCCCCATCTCCCCCATCCTCCCTATCTCCCCCATCTCCCCAGTGACTCCCCTGCTGTAAAATAATCAAAGTTTAATAACAGTGAGCGATCGCCACTCCGGTTGGATTTTCGATGGCTTGAGTTGGCAATCGCCTGGTACCTGATATTTGAAAGCGGTGGGCATGAGTAGCATTATCAAAGTCACAGATACTGAGTTTGGAACCGAAGTAGAACAAGCAACAACCCCAGTATTGGCCTATTTTTGGGCCAGTTGGTGTGGGCCTTGCCGATTGGTCTCCCCCTATATAGACTGGGCCGCATCAGAATATGGCGATCGCCTCAAAGTCCTTAAGCTCGAAGTCGATCCCAATCCTGAATCAGTGAAAAAGTGCGGCGTTGAAGGAGTACCGGCAATCCGCGTCTTTAAAGATGGGGCGATCGTAGAATCCTTTGAGGGAGCCATTACCAAACAGGCATTAGCCACCCTGATCGACGCCCATCTCTAAAAACCCACTGGGACTCCCTAACCGGACCTGCTTAATGATGACAGCCTGCGTAGGCAGGCTTTGTCCGCTTTCCGCCCCACCCTTGAGGGTGCGGGTTTAGCAGACCCAGGTAAACCGGATTCCGGATCAGTTGCACTCCATCAGCTTCTCACCCGTTAACCATCATGCAGTTTGCTAACCGTCTAGAACCCCTGCGTTCCAATGTCTTTGCAGATATGGATAATGCTAAAGCTAAGGCTAAAGCCGCAGGATTGAAGGTCATTGATTTATCATTAGGGTCCTCAGACCTACCCCCAGCACCCCATATTATTGAGGCGATCGCCTCATCTTTACCCGATCGCAACTCTCACGGATACGTCCTCTTTCACCGCACCCAAGCCTTTCGCGAAGCTGCCGCCCGGTGGTACCACCAGCGCTATGGCATTGCAGTAGACCCCCAAACTGAAGTCCTGGCGTTAATTGGTTCCCAGGAAGGCACTGCTCATTTACCCTTAGCCATTTTAAATCCTGGAGATTTTGCCCTCCTCATGGATCCGGGCTATCCCTCCCATGCCGGTGGAGTCTACTTAGCCAGTGGTCAAATTTATGGGATGCCTCTGCGGGAAGAAAACGGATTTTTGCCCGTCTTTGAGGAAATTCCCCAAGGGGTTCTCAACCAAGCGCGGATGATGGTTCTGAGCTATCCCCACAACCCCACTACCGCCATTGCTCCCCTGTCGTTTTTCCAAGAAGCAGTCGCCTTTTGTCAGCAGCATCAGTTAGTCCTAATTCACGATTTTCCCTACGCTGACTTAGTATTTGATGCTCAGATTTCCGTCCCTTCTGTCTTGCAAGCGGACCCGGAAAAAACTGTTTCTATCGAGTTTTTTACCTTGTCCAAATCCTATAATATGGGCGGATTACGGGTAGGGTATGCCATTGGCAATCCCGAACTGATTAAAGCCCTGCGGCAAGTTAAGGCAGCAGTGGATTTCAACCAATATCAGGGCATTCTCAACGGAGCGATCGCCGCCCTCACGGGACCCCAAGACACCGTAGGCGAAATGACTAGCATCTTCCGCAACCGTCGGGATGCTTTCGTTAACGCCCTCCATCGTATCGGCTGGCAAGTGCCCATGCCCGAGTCTACCATGTATGTTTGGGCCAAACTCCCCGAACAGTGGGCCAACAATTCCATCGGCTTTTGCACCCAGATGGTGGAAAAAACCGGCATAGCCGCTTCTCCCGGTTCTGGATTTGGCAAAATGGGTCAAGGGTATGTGCGTTTTGCCTTAGTTTGGGATCCGCCGGTGTTAGAAGAAGCGGTGGAACGAATTGCCCAGTTTTTGAATTCATAATTTTACCCAGTCCCCTAGTCCCACAGAATAACCGATGAGAGAGTCTCATCGGTTATTTTTTACAAAAGCCACACCGGGAAAAGATTTGAGTAAAACTGCTGCCCTGAAACGAGGCAAGTTTAGCAAGTCTTTACAGAAACTTTACGAGATTCCATCATAACTTTATGGAAGGTGAGAGGGGTCGCGGATAAGATAAGGACAGATAGACAGAAATCCTATTGTGATTACTTAACCTTAAAAGTTGAGACTCTCTCAGATATAAAGGGCGGCAAACCGACCCAATCCGGAGCCAGTGTATTGACTGGAAAACTTCCTAAAAAGCGCGCCTTTAAAGTGATGGCGATCGCACCATCCCGGGAAACCCCGAGATTTAATGAGACATCCGCAATACCAAGCGGATTCCCCAACCTAAACCCACTTGCACATTCTTGAGGAGACCCCCACCATGACCGGACTTGTAAAAAAACTCGCGATCGCCACTTCCGTTGCTGTGGGTATGACTGCGATCGGTAGCGCCCCCGCCTTTGCCGGGACTTTAACAAATCCCCAATTTGGTGGAACGGCTGCCAGCGACTACTTATCATACTGCTCCAATGGCAGTAGCACATACGCTGGACCCACCTGCACGGATTCCTTATCCACTATTCTCTCTGGCAATAGCAGCGCCCCAGGTGGCAACATCGAATTAGCCGCCAGCAGCGAACAAGGTGGGTTTGATTTTACCAAAAACACCGCATTAACGGGCAAAATTGGTGGCAAAGATATCGTCATCAGCAGCTTAACCCAATCCGACTGGATGAGTGTTCTGGGCAATGGCAAAACCTTACTGTCTCAATGGTTAGACGATGCCTTTTTAGCGCACAGTATATCCAGTGAGTTCAAACCATTCGTTCAGCAGGCTTTTCTCGCAAATAATGGAATGCAGCGCTTCAGTGACCCCAATATTTCCTATGTTAATCAGGATAACGCCACTGGGGAAATCAGTATTGGACTAGCAGGACACTTCAATGCTTCTAATATGTTGAAAGAGGCGCTGGGAAACCATCCCCTGTTGTCCTTATTTGTACCCAACGAGGTAAAAGCCAGCGAACTGGTTAAAGTGATCTATGACAATGGCCCCGCTAAATTTCTATATAGCTTCACTGCCACCGATGCGCTTCAAGCCAACAAGCACGGCGTCGGTGCAGATGGGGTATCTCATAATGGGAACTATGAAGTTAAACTAGCAGGGGTCCCAGTCACCTCAGTTCCCGAACCCTCCACCATGCTTGCTTTAATGGCAGTGGGCGGTCTAGTTGCCACCTCCAAGCGTAAATCCGCCAAAAACGCATAAGTTGGCTGATGGTATAAGTTTGACACATCCGTAGAAAAAGGAAGCCTCAAGGCTTCCTTTTTTTTATCCAAAACATCAGGCAAAGGATAAAGGGGAAGTTTCCCTCGTTCTTAGTAACGACTTTAGTCCTTCTCGGGTAACAACCTTAGTGATTATCCCCCTTACAAACTAGCCTGCAACTTATCCAATAAGCCCTCGATATAATCTAAGGCACTGGCGATCGTCTGGGGATTTTCGATATCCACATCTACATACTTCCGCAACGCCTCCACCTGATTCATACTCCCACCGGCAGCCAATAACTCCAGATACCCGGGAATAAAATCTTTACCTGTTTCGAGATACTTTTGATAACAGGCTAAACTCACAATATTGGAAGCAGCGTACTGATAGCAATAAAAAGGCTTAAAGAAAATATGCCCAATCCGCGCCCAATCATACTGGTGTTCCGGTAATAATTCTACCGCATTGCCACAGAGATTGCGATACAACTCCATCCACTTGTCATTGATGAACTTGGCATCAAAACTGCCTTCTTTGGCGCGATCGTGAATCGCCAATTCCAAACGACTAATCGTACTTTGCCGAAATAGTAAATTGAACTGGTCCTCCAACTGTCGCGTCAGCAACGACTTCATCAGCGCCTTATTATCTGCGGCAGTTTTCAGCAGGTAATCCAGCAACAGCAATTCATTAAAAGTCGAAGCAATCTCTGCTAAAACCAAAGGCGGATTGCTATTATAATAGGACTGAGCATCATCAATCCAAGCAAAATGTAAACCATGACCCATTTCATGAGCCAGGGTAAACAAAGAATTGTAATCGTCCGTGTAAGAGAGCAATAAATAACTATGTTTACCGTGAGAATAGGCACAAAATGCCCCACCCCGTTTGCCCGGACGAACCTTGGCATCAATCCAATTTTTCAGGAAAAACTCTTCTGCACGCCGCGCATAATTGACATCAAACTCTTGTAAGGCATTCAGCAAAGTTTCTACCCCGGTTTGATAGTTGACCGGGGGTAAAGGTTCCTCCTCCTCTGTCGTCCAAGGTGCATAGAGGTCACAAATCCGGATTTTTTGACCGAGTGCCTTTCCCTTGAGTTGATAGTAGCGCTCAAACAGTTCAAACCGACTCGCGGTCCCGTCCATAATGGCACGGAAAACAGGTTCAGAAACCTCATCGGCCAACAATTGCTTATGCAAAGTAGAGGAATACTGGCGCATATGACTTTCGATGCGATGATCCTGCGTGACGGTATTCAGAATGAACCCGTAGAGGGAGTTATGCTGTTTGAGAACATTTCGGACGGAGAGATAGGTATTGTACCGAACTTCTGGGGAGGGATGAAACAACAAGGCACTCAATTCCGCCTCATTGCTGGCAGTTTTGCCATCGGGGGTCGTTACAGGTTCATATTCTTGTTCTCCCAAATGCACCGATCGCAATTGGATAAACGCTTGCCGACCCGTGAGACTGTCTTGATTGCGAGTTTGTTCGATTTCTTCGGAAAGCGTGTGAGGACGAAACTCCGCAATGCGATGGAGATAATGGGTATAACTTGCCAGTTCCCCAGAGGCGAGTAATTGGTTAAAATTTTCTTCAGAAATCTGCTGTAATTCGAGGTCAAAAAACAGCAATTGATTCTCGATCGCCGTTAGAGATTCCATCACCTGATCCAGCAGTTGCTTCGCTTCCGTATTGCGCGTATCTGCTGAAAAGGTTAGAGAAGGATAGGCATAGACATAACCAGAGATTTGACCGATTTCTTCCAATTCTTGTAAACAATCGGCGATTTGCTCCGGGGTAAGTGCGGCGACATTGCCGCGATAGGTGCGACGAAACCCCGCAGCACGATGCTGAAGGACTTCTAAATCCTGCTCGATCTGTGGGTCGTCAAACCCTTGATAAAGGTCTGATAAGTCCCACTCCTGGGGATTTTCTAATTGAGCGATCGCCGGGGATTGAGGGGTTTGAACCAAAGTAACACTCCTTTGTCACAGTTTGCTACTTCTATTATGAGGGAAATTTTCCCCATTATCCACACCCAGTCCGGGTACGGCAATCCGAACGGACTCCTTTCTCCTATCAGGCGATCGGATTCCGGTGCAGGTAAACTAATGTAAACTCTGGGAATTATTATAGACCTTTTTAGCCTAAAATTAAACATGAAACATGGCAATTAACCTCAAGGATAATGGCGATTGACAACTTATGTAAATACCTGGCCACGAAATATCCACAACGCTTTGCCGCGTGGATATTGCGAAGAATCATTACCTCACCCGTGGAGGTGTTAAAAACTGAATTAACCCTAGAACCCGTGCGGGCCGATTCAGTGATTTTTTTACGGACAAACCGGGAAATTTTGCATTTAGAATTTCAGATAAAAGTCCCCACGGATAGACCGATGCCGTTGCGGATGTTAAATTATTGGGTGCGGCTATATTGGCAATATGGACTGCCAGTGAGACAGGTGATTATTTGGCTGCAACCCACCAGCAATCCAGCGGTGTTTGAGACAGAATTTGTCAGCGAAAATACCCGACATCGATATGAGGTCATTCGGATTTGGGAGGAATCTCCCGAACTGTTGCTCCAAGACCCAGCATTGCTCCCCTTGGCAGTGTTAGCGGCGACTCAAGAACCGAACCAACTCCTGGCGCAAGTTGCTCAGGAATTGGCTAAAATAGAAGAAACTGAACTGCGCCAAGAAATCGCCGCCTGTACTCAAGTTCTAGCGGGTTTACGGTTTAACAAAGATACGATTGCTAACTTTTTCCGGGAGGAAATTATGCAGGAATCCGTAATTTATCAAGATATCCTTCAAAAGGGACTGAATCAAGGGAAAAAGCAGGAGGCGATCGCCATGATTATGCGTCCGATTACCCGACGGTTTGGTTCCCTAGCACCCGATATCCGAGAACGCATTGATGCACTCACAACGGCTCAATTGGAAGACTTGAATGAGGTCTTATTCGATTTTACAGAAGTCACGGATTTAGTGACTTGGTTGCAGTCCCGTTAAACTCAAGTTGTGGGCCGTTACTGAACGGTCCACAACTGAATCAGTTGTGGAGTCATTTAAACCCGAGTTCAATGGCAATAGATAACTTATGTAAATACCTGGCTACAAAATATCCACAACGCTTTGCCTCGTGGATATTGCGAAGAATCATTACCTCACCCGTGGAGGTGTTAAAAACTGAATTAACCCTAGAACCCGTGCGGGCCGATTCCGTGATTTTTTTACGGACAAATCGGGAAATTTTGCATTTAGAATTTCAGATAAAAGTCCCCACGGATAGACCGATGCTGTTGCGGATGTTAAATTATTGGGTGCGGCTATATTGGCAATATGGACTGCCAGTGAGACAGGTGATTATTTGGCTGCAACCCACCAGCAATCCAGCGGTGTTTGAGACAGAATTTGTCAGCGAAAATACCCGACATCGATATGAGGTCATTCGGATTTGGGAGGAATCTCCCGAACTGTTGCTCCAAGACCCAGCATTGCTCCCCTTGGCAGTGTTAGCGGCGACTCAAGAACCGAACCAACTCCTGGCGCAAGTTGCTCAGGAATTGGCTAAAATAGAAGAAACTGAACTGCGCCAAGAAATCGCCGCTTGTACTCAAGTTCTAGCGGGTTTACGGTTTAACAAAGATACGATTGCTAACTTTTTCCGGGAGGAAATTATGCAGGAATCCGTAATTTATCAAGATATCCTTCAAAAGGGACTGAATCAAGGGAAAAAGCAGGAGGCGATCGCCCTAATTCAGGGGATGCTGAACCGCCGTTTCGGTTCCCTGGAACCCAATGTTCAAGAACGTCTTCAATCCCTCACCCTAACTCAATTAGAAGAGTTGAGTTTGGCATTATTCGATTTTACAGAAGTCACTGATTTAGTGACTTGGTTGCAGTCCCGTTAAAGTTAGATTTAGGGTAGTTAGGGAACTGCCCTAACCCCAATAATTTGGGGTTTTACGGTTGGCTCAAGATTTAATTGTTAACTTTTTTCTGGAGGGAATTATGCAGGAATCCGTGATTTACCAAGATATCCTTCAAAAGGGACTAGCCAAGGGTCTCCAACAGGGTCTCCAACAGGGTCTCCAACAGGGTCTCAATCAAGGGAAAAAGCAGGAGGCGATCGCCATGATTCAGGGGATGCTGAACCGCCGTTTTGGTTCCCTGAAACTCGATGTCCAAAACCGCCTGGAATCCCTGACACTAACTCAATTAGAAGAGTTGAGTTTGGCATTATTAGATTTTACAGAAGTCACGGATTTAGTGACTTGGCTGGAGTCTCGTTAGCGGGTTTCCCCCATTTTTTGGATAGTAGGGACAAGGCAGTGCTTTGTCCTTACTGGTTTGATAGTTGCCCATTGATGACATCAAAAATTAGGCTTTAAGGCGCGATTAAATGCTCCTCAGAACGGCGATATTGGGCTTTGAGACGCGATCGCTTGATGGGAAGCCAGACCATGACTCCAATCACAGGAATGCCGGTGATCGCCGCCGCAGCAATCAGTAACGGGGTCCAAAATCCTAATTGTAAAGCAATGCCACAACTGATGCCAGAGGCGGCAGTTAGCAGGGAGAGCGCAGTGGCGATTTGCAGTCCAAATTCCTTGGTAATCCCCGAGGCTGCTAAGATTAAAGCAACCCCGGTTACCGCTGTGGCGGCTAAGGTGCCAGCGGTGGCCCAGGACCCGATTAGACTGGCCCCGGCAGCCATTCCTAGGGTAAATCCGGCGATCGCCGCGATTAGGGTCGTTGCCACGGAAGTGAGCAGAAATTTTACCACAAATCCCTGCTTTCCCGTCAGTTTAGCAAGCCCCGCCCACCCTAGAAATCCACTCAGGGCGATCGCAATCGGTGTGGCGATCGAATGAAGGGCTAACATTCCTCCGGCACCAGCGGCTAAAAATAACAATCCTAATGAACTATAGGGTAATTTTTGAGTTAAAATTGGAATGGGAGCCGTGGTAATTTCTAGGGGAATCCTAATCGGATTAGGCATCCCATTATTTTCTAATAAAAGTTCTCTTTGATAGGTTTGATTGGCTCGTAATTGACGGGTATCAATAATAATTTTAGCATCCAACCGATTGTTTTTAAAATGAGCAGGAGAAAAAGAAATCCAAGCATGGGCATCGGGACGATGAGGCGGGTCCTGGGGATGGGGGGCAACCTGCCATTTTCCCCGGAGTCGGGTGTCGGGAACGGGGTTTTTAATCGAGAGGGTGTGGGTAATTTGTTCTCCTAGGGTTGAGGCGGTTGCCGTAATGTGAGTTTTGCTCAGATGAACTTCCGGTGTGCGAACGACATAAATCGGTTCTAATGCGGCCAAGGCCGTTGCGGCATCGGGGAACCGCTCGCCCGGATGGGGTTGGACCATTGTTTCTAACCATTCAATCCAGCGCCAACTCACTTTAGGCATGAGATGTTTGAATTGGATGCGATAATCGTCATCAACCAACTCGGCGATCGCCACTGAACGAGTCCCCGTCAGTAAACAAATCAACGTAGCACCCAATCCGTATAGGTCCGACGCCGCAGATAATTGGCGATTCAACAGTTGTTCAGGGGGCATAAATCCCATCGTCCCTTTGACCATACTGCTCATCGCCACATCTTCCGAACCGAGTTTAGCAAAGCCAAAATCTACGAGGTATAACGTTAGGCGATCGCTTACCAGGATATTTTCCGGTTTAATATCCCGATGAATCACCAACGGGGTCCGAGTTTGCAGATAAACTAAGATGTTTAAAGCTGCGATCGCCAGTGCCTTGACCTCATCTGCCTCAAAACTGCGCGGGACCGCCAGGGATTGAGCATCTTTATACTCCTGGACCATACAAAACCCATCGGCAGTCTCAAACGAATCCAAATATTGAGGAATTCCGGGGTGATTTAACTGTTGCAACACCTCAATTTCCCGTTCCACCGCCCGATAAGCGGACCAGTCGGAACCACTGGTGGCAAATTGGAATTGTTTAATGGCAACGGATTCTTGTCGCTGCTGATTAAGCGCCAAATAAGTCACCCGACCCCCGGCGCGATTATGGCCGAGTTCTCGGATAATTTTATAGCCGTTCGCGCTAAAGTCGGGAAAATCATTCATGGTGGGAAATCGCTAGGGGCTGTTTTTATTGTAGGAGATGGGGGAGATGGGGGAGATAGGGAGGATGGCGGTCTCCCCAATCTCCCCCATCCTCCCTACGATCGCAATTGTTTCAACAGAGATTTAACCTCCTCGGGAGTCAAATCTCGCCATTGTCCCGGTTGTAACCCCGCTAGGGAGAGGTTGCCGATGCGCGATCGCACCAGGCGGAGGGTGGGAAACCCAACGGAGGCAGTCATGCGTCGGACTTGGCGATTTTTGCCTTCCGTGAGGGTGATTTCTAACCAGGCGGTGGGGACGGTTTTGCGAAAGCGCACCGGGGGATCCCGGGGAGGGAGTTCGGGTTCGGTGGGTAAGAGTTGCACGGTTGCGGGTCGGGTGCGATAATTCTGAATCTGGACTCCGTTGCGGAGGGAATCGAGGGCCTGTTCGTCGGGGATGCGTTCAACCTGTACCCAATAGGTCCGGGGATGGGCATATTTAGGGGAACAGAGGCGATGTTGGATGGCACCGTGATTGGTTAACAGCAACAGTCCCTCACTGTCTAAATCTAAACGACCGACGGCATAAATGTCGGGGATATCAATGTAATCTTTTAAAGTCGGGCGTTGAATGCCTGCATTCTTGCCGTCGCGATCGCTAAATTGGCAGAGAACGTCATAGGGTTTGTAGAACAGAATATAGTGGTAAGACACAGATTAATTCACTGATGAAAAAATAAACTGGGGTAGATGTGAGAACTTGTATTTTAGGCTCACTGGAGGGACACGGCACTGCCGTGTCCTCAACTCGATGATGGGACAATTTTAGGGGTTGGAGTTCCCTGATAAACTGGTTTTTAACCAGTCTAAAATCAGGGGATTCACCACCTCTGGACGTTCATCATGGGGACAGTGGCCGGTATTGGGAATCGACTTAAAGGTAATGGTCCGGTCCGGGTGAGACTGTTGGAAAATCCGACTGCCGGCGATCGGTGTCCAGGGATCATCTTCCCCCCACAACACCAATAACGGATGAGTAACATTCGGTAAAATCTCCGAGGGCGGTGTTCCTGGAGGTGCGGTTAAAATTGAGGCAAACACTTTTTGCGCCCCCACATCACAGGAAGGTTCGTATAGCAAATCGACCAACTCATCGGTAATCGCCTCCCGGTTGCGATACACTTGGCGCAAGGTATTGCGAATTCGGTGTTTCTGGCGAATTCGGTTAAATAGGAAGGTTCCAACAGTGGGGGAACTCACTAATTTGCTAAATGTACCCATCACCAACCGTAATGGGGGATTCAGTTCTTCGGGTCGATGATTTAACCCCCCGGCACAATTGATTAACACCCCCCCTGCTGACTTTTCGGGGTGATTGGCAACCAGCATCAGACTCAGCAATGCACCAATGGAATTGCCGATAAATACCGTCGGTTCCTGGATATGTTCCGTCCAGAAATCCGTAATCAGTTCTTCCCACAGTTCCAGGGTGTAATTCAGGGGGGCTTTATCCGAACCGCCAAACCCCAGCAAATCTAGGGCAAACACGCGATATCCCCCTTCTGCAAGGGCGGGAATGTTCTTGCGCCAATGGCCGATGGAGGCCCCGAATCCATGAATCAGGAGGAGGGGACGACCGACCCCTTGGACGGCATACTGAACTTTATGGCCGTTCCAAATCCAGGTTTCCTTGGCGATCGCAGTTGGTAGTCTAAGCTGTTGTGTGGTCACGGTCTCTATTATTAAGTTTAGTAAACTCTCTTTATCATAATCTAGGACATCCAGACTTGGAAGGGCCAGAAACCCCACAACCCGAAACCGGGTTTCTAACCCAGATGCTGTGATACCCTAGAAGGAAGGTCCTAACGGGAAGAAGACAAGGGCGCTATAACCTGTAACCTGCTGGGTCAGTACGACTCTGCTGAAATTGAACGAAATGCCATCAAACTTGTCCAATGTTCTCACTGGAGTTAATGCGATGACGATATCATGAAAGCCCGAACAAGAGCAGTTTATAGCAGAAAAATTAAATAGCGGAAAATATACCACGGTTGATGAAATTTTAACCAAAGCCTTTCGCTTATTAGAAGAACGAGATAGACAGTAGGACGAGTGGGTGAAAACAACTCAAGCAAAGCTAGAAACGGGACTCGCCCAACTTGATAGAGGGGAAGGGATTGATGGAGAAGCGGTGATGGCTCAACTCCGAGAAAAATCCCGTAAACTCCGAGAAGAGGGTCAGCAATTAGGGAATTGAAATAGTCCGGATGATGAGTGGGTATCGCGATTTAAACTCACTGCTTTCTGATGCCGACGAGGGAAACTAAATCAGACTAACAACAGAAAGAGTTAAAGAAATTGAGAGAAAGAGGGAAAATTACTATGTTATTGATGCCACTTCTCCGCTAAAATCGATAGAGTAGCGAGTTGAAAGTCATGGGAGAATGGATACAGCATTGCAGTCTCAGAGGAATCGGAGTTATGCCATTATTGGCACCGGGGCGATTGGCGGGTTTTATGGCGCGAAACTCCAACAGGCGGGGTTTGAGGTGCATTTTTTGCTGCATAGCGATTATCAGTTTGTGCGGCAGCGCGGATTAAGAGTGGATTCGGTTTGGGGGGACTTTACCCTCGACTCCCTGAATGTTTATAACGATGTCCACCAAATGCCGCCTTGTGATGTGGTCATTGTTGCTCTAAAAACCACCCGCAATTCTTTATTGACAACTCTGCTGCCGCCGGTTTTGAAAGAATCAGGGGCAGTTTTAATGTTACAAAATGGTCTGGGTAACGAAGAGGCGATCGCACCGATTGTTGGTCCGGCTCATATTCTGGGCGGATTATGCTTTATTTGCTCTAATAAAGTTGGAGACGGCCATATTCACCACCTCGATTATGGCACGATTACCCTAGGGGAATATGCACCGGATTATCAACCCTTGGGAATCACCGCTACTCTCCAAGACATTGCCGGAGATTTTGAAGCAGCCGGAATTCCTATCCAATTTGCCGAAGATTTACTCCTCGCCCGGTGGAAAAAATTGATTTGGAATATTCCTTATAATGGCTTGTCCGTGGTGCTGAATGCTCGAACTGATGAAATCATGAAAAATGAATATACGCGCCTTTTATCCGAACAGTTAATGCAGGAAGTTGGGGCGGTTGCTGCTGCATATAATCGGAAAATTCCCGAAAGTTTTATTCAAAAAATGCTGGACCATACGGCCAAAATGAAGCCCTATATTACCAGCATGAAATTGGATTATGACCACCACCGAACCCTAGAAATAGAATCCATCATTGGCAATCCTCTGCAAGCGGCGATCGCCAAACAAATCCCCGTCCCCAAAATAGCCATGCTTTATGCTCAATTAAACTTTATAAATAGTCAAATCCAAGCCAAATAGCTTGTCCCCATTTCGTAGTAAAGACTTCAGTCGTTCCCGCATCTTCCCCCTAAACCACCCCGCACCATTATGGATGAACGCTTAATCAAACCCGGACTCCCCCAACCCCCCACATTTGATCGCCTCAGGGATGAAAGATTATATCGCAAACAACGCTTGGCAGCCGCATTTCGCCTATTCGCTCACTTTGGATTTGATGAAGGCGTAGCGGGTCATATTACAGTCCGGGACCCAGAATTTCCTGACCAATTCTGGGTCAATCCCTTTGGAATGTATTTCGGTCATATTCGCGTCTCGGACCTGGTATTAGTCAACCATCAAGGGGACATTTTAGAAGGCGATCGCCCGATTAATGCCGCTGGATTTGCCATCCATTCCCAAATCCATCAAGCGCGTCCCGATGTTATCGCGGCAGTACACGCTCATTCCCTCTATGGCAAAACCTGGTCCACCCTCGGACGACTCCTTGACCCTCTCACTCAAGATGCCTGTGCCTTCTATGGGGATCATGCTTTATTTGATGACTATACCGGCGTGGTATTAGACGTGAGTGAGGGCGAACGATTAGCGCGCACCTTGGGAAATGCTAAAGCCATTGTACTTCGCAATCATGGATTACTCACCGTGGGTCATTCCGTGGATGAGGCAAGCTGGTGGTTTATTACAATGGATCGGTCCTGTCAAAGTCAACTGATGGCAGAAGCAGCAGGAAAACCGATTTCTATTGCGCCAGAAATTGCTCAATTGACTTATGCTCAGGTGGGAAGTCATTACATGGGGTGGTTTAGCTTTCAGTCACTTTATGACATGATTGTTCGTCAGCAGCCAGATTTATTGGAATGAATAGGGGGGTGGAGAGAAGAACCCCCAGTTCAATCCAATTTTCCGGGTCCTTTCTTCTCCCTTATTCCCTGAAATTGGAGGCAATTGTTTTCAAAAAACTAATGCTAGGGGCGAAAAAGTATTCACCTCCCTGCATGGTGACAAAGTGATAAAAATCAAATTCAGTGACCTCATTTTCCCCCCACTGATTCGGCCATTTCTGTCGTGCTTTTTTGGGGTTTCCCTGTCCAACTAGGGCATCAAACCCCGTGGTGTAGGTTGCAAAATGATAATTGTTTGACCAGTTCTTTTGCATGAACATAAACTGGTTAAATAGGTCACTCTGAAAGCATAAAAATAGCAGTCCCACCTTTTCATCTTCCCCTGGATATCGCGTCATTTCTTGTAAATGAGCCAATTGATTGTTAAAGCGCGATCGCACGCATAAGGAGTGATTTCGGGCATTGGGAAGTTCGCCATAGCTGATAGCACGACGCACGATGCGATGTTGGCGTTGTTCCTCAATGGTTTGATGTCGGTCATTTTTGTCTCCCCGAGGATTCACTTTACGAATGTGGGCATGAAATGGACATTTTACCCCCGGCAAATCCTCATCATAGTTGAAATTATTAGGGACTGGATCAACATTTTGTTCTGTAGGAAACTGGGTGATTGGCGTTCCATCTCGGAAACGACCTACCACTAATGCTCCCGCTCTTTCTTCCTCTTTTTTTGATAACTTCAAGGTTTGAAAAAGAGCTTTTTCGGCGGCCTTAAATCCGGATACATCTTGTTCAAGTTTGCGGTAAACACAATAGCTACCAAAACTATACTCTCCCTCTCCCAAGGGGTCTTTAACTAACACTAATTCTAAGGGGGCGCTGGGGTCCCATTTGTCGAAACCTTGTTGTTTAGCCAGATCTAGGTCATCTTTAAAAAATGGTAGTCCTAAGTATGTAATGATTCGTTATAATCATGAATAAAATATAATAAGGCCCCTATATGATTGTCTAATTTTTTAGAAAACGATAAGGTTTTTCTAACCAGCCTAGAAATTCGTTGCCTTAAGGTATTATTGAACCGTTCAATATGGCTAGTTTTTCCGCTATTTTTGCTGACTGGTTTATATCGGGTCTTTGGAAAAACACACTCGTTGGAAAAACACACTCGTATGCTTGCCAAAAATCTGTATAACAAACAGCACATTCCCGATACACAGGCGGTAAGGATTCCCATAATTTTCCGCTGATTTTTGACTCCTATCTCCTACATAAAAGCCGACAATTTATCGGGTTTCTAAATCTAAAGCGAGCCACACCCACTGTTGGTTTTGTTTGTTTTGAACATAAGACCAAAGTTCGTCACATTCAATGATTAGTTTTCCTGGGGTTTTAGTTGATACTTCAAGTTCCCTGGAAACCTTAGCATACTTGGCATTGACGTATTTCTGAAGCCAAGTTGCTGACACCTCAAAAACTCTGCATATACCAGCCAAAGGCATTCTTTCCAGTAAGAGCTTGTCAATCCATTTTTTAATCGAGTTGGAAATATATTTTTTACGGTTATTTTGAACAAACTGGCGGCCACAGTCCTTACATTGATGATTTTGCTTACCATTATGAATATGACCATTTTTTCGGATGTTATGGGAGCCACATCTAGGACAGACTGGTTGAGAGGCTTCAAAGTCATTAGACTTTTGGATGGGTTGAGAATTCATCGATTTTTTCATATGTTAATTTCTCTAAAATTTATGGCCCTAATTTAACATTTTCTATTCCAGAAAAATATTTGAATTTTAAATATTTTTTATAAGTCTAGCTTATTAAAGTACAATAATTTTGGCTTTTATTTTTTATCAACGAAGGAGATTTCTATTAGTAGTCTAGCCGCATCATTACATATTTATGACTACCCAAAAAGTTTGAGTGTTCCTCTGGTATGGTTTCCCATCATTCAAATTTTAATTAATCGCTACTTTCCTAAAAATAAGCCCATTTATCTGGCCCTAGATAGAACCTCTAGGAAACAAAACAACCTTTTCATGGGTTCCGTGATTTATCAAAAACGAGCTTGGCCAGTTTATTGGACATTTATTGACCATACAGGAGCCAGCAATCTCGCCCGTCAAAAAGCCATTCTTACTCCGATTATTCGGTTATTAAACGGTTATAAAATTATCGTCGTTGGAGATCGTGAATTTCATAGCGTTGAGCTGGCTCATTGGCTCCAGTCAAAGAAAGTTTATTTTGCCCTCCGTCAAAAATGCAACACTTACATTAAACAAAGTCGGAAAAAAGGCGAGGATTTTGAGAGCTTAAGTAATTTAGGGCTTCAACCGGGTATGAAACTCTATTTGCCCTCAGTTCAATTTACTAAAAAGAAAGGATTTGGCCGCTATGCTTTGGCCGTTTACTGGAAATGAAAGTATCGCTCAAGGAAGTCGAGTGAACCCTGGTATATCCTGACCAATCTTCCGGACTTAAAAAGTGCTTTAAAAGCTTATTCCATGCGGATGGGCATTGAAGCGATGTTCAAAGATTGTAAAACTGGAGGATATAATTTAGAAGGAACAGGAGCCAACCAAGAGCGGTTGACTCGTCTAGTTCTTTTAATTGCTTTGGCTTATACGGCCTCATCTATTCAAGGCGTGCCAATCAAGCAACAAGGAGTGCAATCTTGTGTCGCTCGTTTAACCGAATCTGGACGCTCTCAACGCCGTCATAGTAACTTTTGGATAGGACTTTATGGACTCAGTTGGATTGATTCTCTGGAAAAATTGCAGGAGTTGAGTATCGAGTTTATGAAACTTCACCCCCATAAACGGCCTTTTTATCGAAGGGGCCTAAGAGCTATGTCCCTTATCCAATCTAGTTTCTAGCCGGATTGTCACCCCTTCAGGGGATCTACCACTACCCGCGCACTGCACTCAGAATGCGATCGACCATTTCGGCGCAAGTTTGCCTGCGGCGATCGCGATCGCCGTTGTAAGGTAAAGCTTCAGCACTGGGATTGATTGCTCGCCTCGCTGTATTTCGCCATTTCCCGTTCCACGAAGTAGGGCTGTTTCATTCTCCCGGCCAAATTAGTTTTTGGGTTGTTCCAAAACTTTATCCGGCAGGGGATACAGACGTTTTTTCCTACTTTTTAGCCTATTATTAGCAAATAAGGCTGAGAACCCTTGGGCTGTAAGGCTTACGGTGTAAGGAAAATTTTAGAATGAAACAGCCCTACGTTCCACGAAGGGGATTTCTTTGCCGAGCCAGTAGCAATCTGAACAATAGCCGCAAATATTAAAGGCAGCATTCTCCATTGAGATTAAGCTGTCCTCAACTCAGTCCCCATTTATCTGCTAGAAATGCATATTCAAATGCCACTTCTTTGAGTTTTTCGTAGCGTCCAGATGCCCCGCGATGTCCTGCCCCTTCATTAATTTTGAGCGAAACAATATTATCATCGGTTTTATGTTCGCGCAGCTTAGCCGTCCACTTGACGGGTTGCCAATACGGGACGTTGGCATCGTTCAAACCCGTTGTTATCAATAAATGGGGATACTCCTGCTGCTTCACGTTATCGTAAGGCGAGTAAGACTTGATGTAATCATAGTAAATTTTATTATTCGGATTGCCCCATTCCTCCCAATCAGCTACTGACATAGGCAAGGTCGTATCTAATATAGATGTGAGCGGATCCACAAAAGGCGTTTTTGCAATTGCAATTTTACACAAATCTGGGCGCATATTGAGTACGGCTCCAATTAACAATCCACCTGCACTCTCACCGAAAATCGCCAATTTTTCCTGAGATGTCCACTTATTTTTTATCAAGTATTCCGCACAAGCGATAAAGTCAGTAAAGGTATTTTTTCTGTGTAAAAATTTCCCATCTTTATGCCATTTTTCTCCCATTTCACCACCACCGCGAACGTGAGCGATCGCAAAAACAACTCCTCGATTGAGAAGTGAAAGTCGATTGGCACAAAAGGAAATATACTCGCAGACGCCATAGGCACCATAACCCACAAGTAAAAGTGGCGCTTTGCCATTCTTTTCTATTCCTCGTTTGTAAACCAGGGAGATGGGAATTGCTTCATTGTCCGGCGCGATCGCCCAAATTCGTTCGCTGACATACTCGGTTCGATCGTAACCATTGGGAACTGTTGTTTGTTTTTTGAGAGTCAACTCTCTAAAGCTCATGTTATACTCAAAAATGGAATCTGGAGTAACTAAGGATTTATACTCAAGTCGCAAATTCTCCGTATTAAACTCTGGATTTTTATCTTCTTTAATTTCATAAACTGACTCTGGAAACTCAATCCAGTGTTCTTCTCCTGTAGAAAGCTGGCAAATCCGAACTTTTTTGACTCCTGCTTCTCTTTCATAAATAACCAATCGATCTGCAAAAGCGCTAATTTCTTCGAGATTCACTCCTTCTCGTTCGGGAATAAGGGTCTGCCAATTTTCCCGAGATGGAGAGTCAACCAACGTTTGCATGAGTTTACCATTAATGGCTTCTTCATTGGTCAATATGTAAAATCGATCGCCGTGGTGTTCCAGTTTATACCGAACCTCTACAGAACGAGGATGAATGAGTTTAAATTTTCCATTCATATTATCGTTTTCTAAATAATATATTTCTGATGTAAGTAAACTAATTACCTCCATTAAAATATAAGATTGACTGCGAGTTTTAGAAACAAATACATTAAAAGTTTCATCAAATTCCTGATAAATCAAGATGCGATCGCTGATGGGGTTTCCTACAGTGTAACGAAAGAGTTTATCAGAACGGCTTGTGGCATCCACCTGGGTATAAAAGCAAGTTTGACTGTCATTTTTCCAAACAAAAGAACACACTCCAGGAATGCTCTGGGCGTAGCGATCGCCTTCCACTAGATTCAGAAAACAAAGAGTATAGTTTTCATCACCGTCGGTATCGATAGAATAGGCTAAGGTTTGATGGTTAGGACTGACTTCACACAGATCTAACCGAAAGTAGCGATGACCTCGAGCCAGTTCGTTACAATCAAGAAGTACCTCTTCTCGATTGTCTAAGCTGCTTTGCTTGCGACAAAAAATAGGATAGTTTTTTCCCGCTTCAGTACGCCAATAGTAATAGAACTCACCTTGGCGGTAAGGTACGGACAACTCAGCTTCTTCAATGCGATCGCTCATTTCATCATAGAGGCGTTCTTGCAGTCCCTTAGTGTGCTGCATCATCAAATCCGTATAGTGATTTTCTGCTTGCAGATAAGCGATGAGTTGTGGATCGTTGCGATCGTGCATCCAAAAGTAATTATCTATTCGCTCATCACCATGACAAGATAGGACGTGAAGACATTTGGGGGCGATGGGCTGGGATGTTTTTTCTGTAGTCATTAACCTAAACTTGGCTTAAGCGGTCGATACATTTATTGAACGATGGTCGGGTGGGTAGTGCGTGCCCACCCGCCAAATAAGTAGGTAGGTACAAAAAATCGAAACTAAGTAAAGATATGTTAAGGAGAGGGGCCAGACTTAAACTTAACCCGTTTGGCTGTATAGTTTCCCTCTACACTTCGGGCCTCTACACCTGCCATAACCGCATAAGCTAGGTCTAGTTCATCTTCAAACATACGTCCGGCTAATTCATCACGTTTCAAATGCTGCCATTCTAATTCAATTTCATTCATTTCTGAGCAGTATTTAGGGAGTAAAAAGATGTACAATCCTTTCTCTTCCCATGAAGGCCATTTGTTTTGAACCTCTAAACTTTTATGAATCGGCCCATTGTCTTGCACTATTACCCGAATTCGTCCTGTTAGGGCCAACTCCTTTGAGGCTTCCTCCGCTTCTATTTCCATCATTTTAATATAAGATTTACTGGTGAAACTTCCAATGGCAAGGCCATAGGTGAAGCCAATCTTGGGTTGCATTATTCCTAAAATGCTCAGTCTTCTCCCCCGTATGCGCGTTTGTTCTTGACATTTTTGTTCCTTTTTTGGGAAATAGGTATAACCGACTGAACTCCATAAACAAAAGCCCGACTCATCTAAATACTTTAGGTCAATTTCTCTCGCTGCTGCGGCGAATTCCAACATATCTAGATCGGCTTGTTTTATCGAACGTTCTTCTGGGTCTTGCTTATTTTTATGACTAATTCTTGTCCGTTTCCAAATTATTCCCTTTTTTTTTAGCACCCGTCTGAGACGATCAGGACTTAGGTACACTTGCCGTTCTGCCGCCAGTTTTTTAGCCAGTTGTTTACTGTTATAGGTGCGGGGTTCCTGCCTAAGACATTCTTCTACATAAGCTATATCAGCATCTTGCCATTTTGCTTTGCTTCCTCGCCCCGCTTTGTCCCACAGTCCCCCTAGTCCCTTCTTCTCCCACCGATGCAGTGTGTCCCGGACTCTAGAAACAGACCAGTTAAAGTGACTAGCAATCTTTTCTACATACCATCCATGAGCATTCAACCGGACAATGGAGGCTCTATCTTTTACCCTTTGAGGTAGAGTGGTTGCCATTCTAAGTTCAAACAAGGTTCGATCTTCTTCTGGGGTAAGAAAGACTCTCAGGCGAGCGCCCATAATTTTTTCCTCTAACGATGGGACAGGTCTTTACTTATCTTTACATACTTTGGATTTTTTGTACCTACCTACTTAGCTTCGTCACGCAGAGACAAACCCAATCCTGCGATCTATCGGTGGAGGAGAGAATTAGGGCGGTCTATGGGTCGCATGATGCTGGGAGACGCGATAAACCCTTCTCTCTATATGAGCAGTTTTAAACCGCTACCGGACTGGAAATGTTGAGTCCGTAAAACCGACTGGGGTTATCCCAAAAGATTTTTTGCAAGGTTCCATCGCCCAAGCGATCGCTTTGAGCAATCAAGTCTGCGATCGCCTCGGGTCGATGATCCATGTGGGGAAAATCAGAACTAAATAGCAAATTGTCCGCACCGATACAGTCGATCGCCTGCTCCAAATACGGCTCGCTCGGTTCCACCGAAATAAAGCACTGACGGCGAAAATACTCTGATGGCTTCATTTTCACATTCTCTTTCACCTCCCAGCCAAACAGTTCGTATTCTTCATCCAGTCGCCACAACCAATAGGGCAACCAACCGCAACCGGATTCCAAAAATGCCACTCGCAGTCCCGGATGTCGTTCCAACACGCCGCCTTCAATCAGCGCCAACATCGCCATCATCTGTTCCATCGGATGAGAACAGGCGTGGAGAGCGAAGCGGGTGTTAAACCGATCCGCACCGGTTGCAGGCAAGCGGGAATGGGTGCCCTCATGGATTCCCACTGCAATTCCTAACTGTTCGCAAGCTGCCCAAAAGGGTTCGTAGGCCGGATCTGAGAGCAGTCGTCCCTTGACCGGATTGGGACGCAAAAAGACCGCTTTCCAGCCAAATTCGGCGATTCGCTGCACTTCCGAGACCATCTCCTCCGGGTCGTGCAGACTTATCGCCCCCACTCCGCGCAGGATGTGAGGGTCGTAGCTGCAAAAGTCTCGCAACCAATTGTTATAAGCGCGGGTGAAGGCACCGGCAAGTTGCGGAGCCATTGTATCCACTGCAAACAGCCACAGTCCCATCGTCGGATACAGAAAACAAAACTCTACCCCCATCGCTTTCACCGCCTGAACTTGAGAGGCGCTGTCGTAGCGAGAGATGCCATAGCTGTGGAGATCGCGCAGGATGGCACTCAGTCCAGCTTGCTGCAGTTCTTCCGAGATTTTGAAATAGATTTTCTCCCCGTCGATTTCCATTTTAGGAGAGGGGGCACGGTGTTTAAAGGCGGGTTCGAGATACTCTTGCCACATTTCGATCGGTTCCAATACGTGACAATCGGCATCGATAATCTGATAGCGGTCAAACATGAGGGTTTTCCTTTAGAAAAATGCGGGCAACGGATTTAATTGCGCTTCGGTGAGGGGTTCGCTCACCCATCCCATTTGATCGGGCACGTCATACAGCCGACCCGAGGCAAATCTCGGCCAAAAGTGCCGCAATCCGGGGACGACAACTTTGACCACCGATAAACTGAGGTCGGGTCGGGTTTGGTTGACGACGAGGGTTTCCATGCCTTTGGCGCGAACTCGTTCGACGCAGGCGAGAATATCGGTATGCAGATCGTCACTCCAGCAGTGGGGATAGTCGGGGCGAGTTTTTGGGGCTTGGTTGGAGTCGGGAAGCAGATAGGGGTGGTTGGCGAGGGTGGCGGTTTCCCACCAGTCAATGCCTTCGCGATCGCGATCGCGGTAGGCAGTGGTGGCATCGAGAATGCCATAAAAGGCGGCAGGTAAGGACTGGTTGAGTTCGGTTAAGGCGCGAAGCAGAGCGAGGCGGGGGTCGAAGTGAGCGCCGAATCCCAAGAGGATGTTTTCCGGGTGGCGATCGCGGCGTGGGGAGATGGCGGCGAAGGTGGGAATCTGCAAGTCAGCAGTCAGATCCAGTACCCACAGATCGCGATTGAGAGTGCGGTAATACTCTTGCAGGCGATCGAAGTAGGGTTCGTCAAAACTTGACAGTTCTACTGCTGGTTTGCGTAAGCGATTGTACCACCACAGGGCGATGCTATCTCGTTCGACTAGCTCTAAAAATCCTTGGAGGATAGCTTCTTCGAGGTTGTTTCCGGCAGCGCATCCATTGCTATCGGCGCGGGTGAAGTATGCTTGATGCTGTTGGGAATAACCGGAGTAGCAATAGGCAGTGGGGAGATAGCGAAGTTGGTTGTGGGTTAATGACCATGCAGGAGTCCATTCGATTTCGGCATTTTCGTCCAAGGGTTCGGGAATCCAGTCAAAGGTGATGCGATCGCCATTGAGTTGGGTGCGGTTCTGGAATTGCCGAGCGCTAAATTGCATACAGGCGTTGGGGTGAATGCCATTGTCTAAGTTACTCAATGTGCTACAGATGCGCGGTTCATCCCCTTGAAAGGTTCCGGCATAGCGTTCGATCGCTTCACACAAGGCGCTGACTTTGGCCTGAATGTCTTGTCTGCCTTTGCCATACGCTTCGGTTCGCAATCCTTCCTGGAGGTGGTGCAAGTCTGGGAATGTTCCCACTGTGGGATACTGAGCGCGATAGGAATGGGTCAATCCGTCAGGAGTTTCCCAGGTGGAGATGCGCTGTAGGGTGGCGATCGCGCCGCAGATGGGACTGATGCGATCGGCTAAGGTATTGTAGGTATAGTCTGGGGAATGGCTGCGATGTCCGCCATCGCGGGTAAAGGATTTGGGGCGCGATTGCAGGACGATCGGGGCGAAGTGAGCGATCGTCAAGGATTCGGGGTTGCCACAGCAGGGACATTGGGGACGTTGCCAGAGTTTGTGATAGCGCTGTTCCCAGGTGAGGGTGTTGAGGGTGAGGATTTGACCTTCGAGGCGGGAGTGTTGTGAGGCGATCGCCCATTTTGCGATTTCGGTGGCGGCGATGCTGAGAGCGGTTTGCACCGTGGCGGGAATTGCAGCAACGGCGGTGGGGAGGCAATTTTCGGTCTGGTGGTGTTCTTGGAGATAGCGTTCGAGGGGTCGATGTCCGCGCAGGTAATGGGCGAGACAGTGCCAGCATCCGGTTTTGCCGGGGATAAAAATCGGGCCGATCCACAGTTCGACGCCTACGGGTTTGACTAACATCCAAGGGCGATCGCGCTGGATGGCATCGCGATTGCAGGCATCAAGACCGGTTTGCAGGTAGTCGTCGGTGAGAGCGACGGCAAAGGTTCCTTCGTCACTGCAGTTTATCCCCAAGGAATCGAGTTGGGTGGCAAAGGGATGGGGGTCGATGTTGCCATAGCTGAGGATGGAGAGGGCGATTTCCTGGAGGCGGTGGGTGGCGATCGCCGGTTCGATGCCCTGGATTTGGTAAAAAGCGGCGCGATCCTCGGGAATCGAGTCGGTTGATTCGATAATGTACCCCAATTCTTTCAAGCGATCGAGCAAAGTGTAGATTTCAAACACCGAGAGTCGATCCTGGAGGCGATCGACGATTTCTGTGACGGTATAGTTGCCATTGAGGAGGGGAGCGAGTAGCGTGTAGGGGGTGCCTCGCAATAAGAAACGATCGGTTTCCGACAATAAAAATACCCCTTCTAAAGGCATCGTTTCACACCGAAACTGCGGCTTAAACATCGGTTTTTTCAGCATCGTTCTGGAACGCTTGGTGTTTTTTCATCTGTTGTCCATCCAGTTTAAAGAGTAGGGTAGGTCATGCCCACCCTACGGTAGATTGAATTCGGAAAAATCGCCTTTAACTGACATCTTGTACCATTCTCAACAAGCCTCTGTCACTTGAGGATCCGGCGTGGGTTTAAACCCACGCCTCATAGCGTTCAGCCGGTTTCCAACCGGATAAAAACTTTACCCTACAAGCATTTCAGTCGGTTTTAACTGACATCTTGCACCATTCTCAGTAAGCCTTTGTCACCCGACGATCCGACGGGGATTTTAATCAGAGCCTCATAGCTGAAGTCGGTTGAAAACAGACTATGAGACTTACCCCACAAGCTGTTCAGTCCACTAAGCGCGGAATGAACGCTATTAGCCAGGGGTTTATAACCCAAGCGGGGGTGTTGCAACTGGTGCAAGATCTGAGTTTTAACCGACTTTAGCTGTTAGACGGGGATTTTAATCCCCGGCCTTGCTAGTGCAAGATCTCAGCTTTAACAGACTCTCAAAACGCCGTACAATCCATCTTGATTGGCATAGGTATAAAGCTGTTCTTCGCTTAAATTGCCCCGTTGCAAATGTTCTGGTAGCGGAGGAAGCGCCAAGAATCCCTCTTCAGAATTGGGATCGTTTACATATTCCAGAATCGTCTGACAAGCTTGGCAGAGTTGTTCCGAATCACTACTTTCTCCGCTGGCGATTTGCTCGATCGTCTGTCTTGGATCTTTATTCAGTCGGCGCAGAAACTCTCGGTCTTCCTGACTCCAGGCATGGGCGAAAACGCGCGCCCAGGCATTTCGTAATTCTTGTGGACATTCCACTGGAGAGTTAACTGCGGGTTTTTTTTGCAGAGTTATTGTCATAATTGACCTTTTTTCAATTTTTAGAATGTTCCTGAAGTATTGTGGAAGGTCTTGTGCTTTTCCACAAGCTGTACGGAATAGCATGGGCTAACAGGTGAAAATTTATTTCACCTTTTGGCTTTTAACCCTCGCTTTAGCTTTGCCGCATAATTCCGTAGAGTTCGCTTTGATTGGCATAGAGATAAAGCTGTTCTTCGCTTAATCCTTTTAGCCCCTCTGGTAGAGTGGGAATGGAAATGTAACCGTACTCGCAGTTATCGTTATTGACATATTCGAGAATCGTGGCGCAGGGGCCTTGGATGCTTTCTGGCGTACCCGAATTCATAACATTGGTAATGGTGACTTTTGGATCTTTCCGCAATCCTTGGAGAAATTCCCGGTTTTCAGGAATCCAAGCATATCCAAACAGGCGAGACCAAGCATGGGCTAGGTCTGGCGGATAGGGTGTTTTATCCATCGTTTACCTACTATTACCTACTATTAATTGGAAGGGTTCGATCGCCTCATCTCGATCGGTTGCCACAACTCTACCGGGAGCAATATTTTTCTGTCAAGATTTATTTACAAAAATTCACAATGCCAACAAATATTGACAATTGGGGCGATGCGACCCAGATACAGCAGATGTAGGGTGGGCAATGCAGCGAACCCTTCTAAATTTAGAAATGTCAGTTCGCCATTGCCCACCCTACGGTATATTGAGCAGATGTAGGGTGGGCAATGCAGCGAACCCTTCTAAATTTAGAAATGTCAGTTTGACATTGCCCAGCCTACGGTATATTGAGCAGATGTAAGGAACTATCCATGTCAGTAGATTTAACCCAAACCCATATCGATCCGCAGGATCCGATCTATCAACCGTTACTAGAGGATTTACAGGCGAATATCCTCAAAAGTCACGATCGCGACTACTCGGCTCATCTTTTTCTGCAATTCAAACCGAACCCAGATGCAGTGCGACAGTGGATCGCCCGGTTTGCCAAAGACCGGATCGTTTCAGCCAAACAACAATTAAAACGATACAACGATCTAAAGACAACATCCCGTTCTGAATCCTCACAACTTTTTGTTAACTTTTTGTTAACCTACCCAGGATATCAATCTTTGGGATTTAACTTGACAGCAGGCCAACTTCGAGAATTTCCCAGTCCAGCTTTTAAAGTGGGGTTGGCTCATTTTCAGACCATTTTGGACGATCCCCCAGTGGACGCATGGGAAGAAGGATTCCAACGGGAAATTCATGGGGTGGTGATGCTGGCAGACAATAATTGGGAAAACCTGCAAACCCAAGCGCAACAAATTCTGACAGAACTAGAAGAAATTGCCGAAATTGTCAATACCGAAGTGGGTCGGGTTTTGAGAAATAGTAAAGGAGATGCGATCGAACATTTTGGCTTTCGCGATGGCGTCAGTCAACCGTTATTTTTCCAACCCGATTTAGATGATGTTGCAAAACAACAAGGCATCGATAAATGGGATCCGAGCGCACCGTTAGAATTAGTATTAGTCAAAGACCCGTTAGGTGAAGGTGACTATAGCTTTGGCAGCTATTGCGTTTACCGAAAGCTGGAACAAGAGGTCAGCAATTTTAAAGCAGCAGAAAAAGCCTTAGCCAAAGCGTTGAAACTTTCAAAAGAAGAGGAAGAAAGAGCGGGAGCATTGGTGGTAGGACGGTTTAGAGATGGCACGCCCCTGTCCCTAGCAAACGCCGCACAAAATGCCGATCCAGTGCCGAATAATTTTAACTACGATGACGATTTGCGCGGGGTGAAATGTCCGTTTCACGCACACATTCGCAAAGCGAATCCCAGGGGGGATAAAAACGATCTCCATCAAACCTTAGAGGAACAACGCCAACATCGTATCGTGCGTCGGGCGATCAGTTACGGGGAATTGCCGATCGCCCGAGATAAATCCCTATCGGTGCGATCGCGATTCGAGGGTCAACTCGCTCATTTAAAAGACATGACTCGACATCCGATCGCTGATGAAAAAGTCGGATTGCTGTTTTTATGCTTTCAAGGTGATATTTTCAACCAATTTATGTTCATGCAAAAAAACTGGTCAAACAATCAGCACTTTGTGAGCTATACCACTGGATTCGATGCACTCGTCGGACAGGGAAATCCCAAAAATTTACAGCAAAAGTGGCCTCAATCCTGGGGAAAAGAGGGTGCGATCGACTTTGATTTTTATCACTTTGTGAAGATGAAGGGAGGACAATACTTTTTTGCCCCCAGCATTAGTTTTTTAAAAACCATTGATTCGCAAAAGTGAGTCTGCAATCCAAAGCGGCGATCGGTTCGTCCAGTTTTCTCAAACAAAGCCTCGCACCCTAGAAGGGTGGGTCTATAGGAACGAAGCCCGCCTGCGCGGGCTATTTTTAACAGCTTTTCCTGTTCCCTGTTCCTTGTTCCCTGTTCCCTGTTCCCTGTTCCCTATTTCTGCTTCAACACCACAATCGTAATAAGCTGTCGTGCATTTAGATTTTATGGTATAATAAAAAACGAAAACCTATAAACCAAAAAAATGCCAGCACCTAATCATCTTAGTGAAAGCCAACAAGAGATACTTTTGAACGAATTACGTGAAAATGATAGCCCCCTTATTCGCGATAGAATCTTAATACTACTCCTAATAAATGATGGTAAAACCTATGAACAAGTGGCGAAATTTTTGCAAATCTCTTATCCAACTGTAGCATATTGGGTTAAACATGGCGATCCAGATAAATTAGAGAGTTTTAAAGATGGACGAGCCGAAGGAAACCACAAAAAAGCTACAAAAGAATATATAGATATGCTCTTGGATATTATTGATAAGGAACCCTCGAAATTCGGTTATGAATTTGGGAGGTGGACATCAGCAAGATTGGCAAAGCATTTAGAAAAAGAGACGGGAATTCACCTGAGTGAATCGCAAGTGCGGAGAATATTAAAGTCAAAAAAGTATGTATTCCTTTGGGCAAAATATAGTCTTGAAGACCGACAAAATCCGCTTAAACGAAAAGCGTTTAAAAACAGATTAAAAGAATACTTAAAAATTGCTAAAAGATACCCAAAGCGTTTACAGGTATGGTTTTGGGATGAGACAGGATTCAGTTTACGGATCGTAAGAAGAAAACAATGGACTAAAAGAGGAAAACGTAAAACCGTGAGAGGAGATAGAAGGAAAGGCCGAATAAATGTAATGGGTTGTCTAAGGGCAACTGACAAAAAAAGAATTAACTTTTTTGTAGAAACAGGTTGTGGTGAATCATTTTATGAAAGTTTAAAGTCTTTCTACGCTTTGGTCATACAGGAATGGGTGGAACAAGGTAATTCCGAAGAAGATTTTTTAGAAAAGGGGCCTAAAATAGTTATTATTTTAGATAACGCAAGCTTTCACAAAAGAAAAGATATTGCCAAGCTTGCCACAGAAGAAATGCCTAAGATATTTTTAGAATATTTACCCGAATATAGTCCGGATTATAATTTAATTGAGTTGGTTTGGCATTCGGCAAAAGAATATATAGCCAACAAGCTATTTGAGTCAATTTCAGAACTAGAATCTATTTTGCATAGATTGTTAAATGAAGGAGAACTCATTATTAACTGGGGGCGTAAAATCAAAAATAAAGGCAATCAGGTTTATTAAAACTAAATGTACGACAGCTTATCATCAAATACTTTTTGTTCGCCAATATGCCGACGCAGGTCAGCGATCGCAGCGGCGCGCATTTCCTCAGGGGAAAGTTGCCAGTTTTCTCCGATAATTTGGCAGAGGCGTTCTAAGCCGTATTGTTCCCCATCGAGATTTTCTGCTTCGGTAATTCCGTCGGTATAGAGGACGACGGCATCCCCCGGATTTAGTTCTATCTGAATTTGACTGATAAAATCGGCAATTTCCGTATCCAATCCAATGAGAAATCCTAAATCCATCGTATCGATTTGCTCTACAGTGCCGCCGGTTCGGACCACTAGCACTTCTTCATGTTGACCGCTAATGGTCAGGGTGCGATCGCTATAATCCAACAAGGCCAACGTCAAATTTTTCTCGCTTCGCATCCGCACCACGTTATCGAAAATCGTGCGATTCACGGTGGTTAAAAACTTGACATAATCCGTCTCTTCATTCACCATTAAGGGATTTCCAAAAAATAAAATCGTCATTTCTCAAACAGGATTATAGATGATATCTACAAACCATTTGCCTAAGTTGGTCTGGTTATCTGGATCAGCATTTGTCAGTCTATTTAGCTTTTTTTCCACCTTTTCCATTTCTTTTTTCGTCAACTTTACTCCAGTTGGATAGGTTTGAGTAACCAACTCAACTTGGGGATTTTTCCCCTTCCATGTCATAGTTTCTGCAAATTTTAAAGCCGTCATAACTTCTTCAATAAGACTGCCATTCCAATGATGTTCTAAGGCGGACCAAGTTCGCTCTATGGGATTATATTTACTGTGATAAGGAGGGTAGTATGCTAGACGCACGTTGATTTTATGACCCCAAACAAAATCCACAATTCGCTTCATAAATTGAGTTCGCCGGGAATGATTCTCCGGCCCGTTATCTTGTTTGATTAAAAGGGTTTTACAGCTTGGAAATTTGTGCTTAACTTTTGTCCAGAAAGAGTCTAATGTATCTACAATAAAATCACTCGTCACTTTGGATTCTGTAAAATATAGAAACAAATCCTTCCATTCTGGTATCAAAATTCCATAGGGAGTTAGTCGGCTTGATGGGTGAAAATCATGATCACAAGCTACTGTTGGTACTCGGGTTTTTCCCCTCGTGAAAACGGGCCAATGTCAACGGCAGCCTTGGCATCCATTGAGATTTCCAAGGTGGTAGGGTCTTGGGCAGCCTCACCAGTTACTCTACTCATTTGTTCAAAAATTTCATCAGTCTCGGGAATTTTTTTTTGAGGTTTAAACTTGGTGACTTTCTGAGGATAATACCCTAACTCATTCAATTTTATCCGGATTGTTTCTGTGCAAGCAAGGCAATTCTTCATCTCTATAATTCTTCTGCTCAATTAAAGCCTTTCTAACGCACGAGGCACTCAACCTTCTATATAATCGGTTGGTTTGAAAGGTCGGATCCGTCTGGCTCTGACTATCTACTATGGATTTAATATCGAATAATAAATTAGGGAGATGTATTTCAGTTTTTTTACGCCCTCTAGCTTGATAATTATTTACACAGGTTATTCCGGTCTCTAGCTCCCGAACACCTTGACGAATTATGTCTCTATTCCATCCCAACTCTCGGGCGGCTCGGCTCTGTCCTGCGTACCCCATCTCAATAACTGTCTGGGCCATAAAGCGGCGGCGTTGTGCCCCTTTTAATTGAGAAGCTGTTTCTTTCAATAAGTTTTTCAGCGAATCTGTTAATTCCATCTGGGTTATAATCGGTCTCAATGGCTTGAATTCTTTATTTTACCAGCTTTTTGCCAGATTTATTTTTTGGGACTCCCTAACATAATGGCCGGATGAGAATCTACATTAGCCTCGTCATTAATGGCTTCATAATACCATAGTAAAACTTTACCGTCCACTGCAATAGTTTCGCTCTCTATTGGGTCAATCCCAAAAAAACGAGATAAACAGGCTGAGTAGCGTTGCTGCTCAATTCGTAATAACGTTCGTCGAATCGTACTGTAAGAGGGTAAGCGGTTTTTTTCAGGTTTAAACAATTCCAACAGTTCATCATGGTAGGCTTTTAACCAATCTCCAATCGCTATAAACCCTCGATTTCCAGCAGCAACACCGAGGGTAAATAAGGCTAGACAGAGGCTTTGTTTATGCCGCGTGCCTGCTTGACGTCGGCAATCCTCTAGATCGGCAAATGCTTGAACAATGGCTATCTGAGACATTTTGAACTGACCCGTCGGTGAGATTACTCTGTTATTCTATCACGTCTTACCTTAGAATGAAATAGCCCTGCATTAAATGCAGCAATGGACGATGGATTTATCCTCCCATTGAGTGAAAATTATACATTAATTGAAACTGATGTAGAAGAGGTAAAAGAACACTTAAACATTGACTATAAATTTGCTCACGATCGCATCCAACAAGCAGCCTACTCCTTAATTCCGGAAACCGAAAAATCCTCCGTTCATTGGCAAATTGGACAATTGCTCTTGCAAAATACTCCGGTAAACGAACAGGAAGTCAAAATATTTGCCCTAGGGCGTCGGTTCAGTACCCGGGCTTGACAAAACGGCTGGACTATGCATAACTGAAATGGACGACCCGATTAAATTCAAGCCCTCATTACGGTATAAAGTCTATGCGTCCTCCTTTGTGGCACCCGCCAGTAGAGCTATCAGATTCAGAACAGGTAATTATTAATCGCATCAAAAAAGCCAAGCTTTTTACTTTTCTTCGCCTGAACCGTTTGTTCATATTCGATGATGAGTTTCAAGAAGAACTAAACACCATTTTTAAAGACAGCACAATGGGCAACTGTCCCATCGCACCAGCCCAATTGGCCTTAGCCACTATTCTCCAAGCTTATCTGGGTATTTCTGACGAAGAAGTGATTGAAGAGCTAGTCATGGATCTCCGGTGGCAATTGGTTTTCGATTGTCTACATTGTGAAAAACCCCCATTTAGTAAAGCCACTTTAATAAGATTCAGAAGCGCCTTAATTAAAAAGGCTTTGACCAACGTTTAATTGACCGTACTGTAGAAATTGCCAAGCTCAAAGGAGGTTTTGGTTCGGCTAAGTTAAGAGCTGCATTAGATTCCTCTCCTTTATGGGGTGCCGGTAAAGTTGAAGATACCTATAATCTCTTGGGTCATGCTCTGCGTAAGGCGTTGAGTATAATAGCTGTACAGCAGGGGTGGGGGCTGGCAGAAATTGCCAATGAAGCCGGAGCGGATTTTGTCAATAGTTCTAGCTTAAAAGCCGCATTAGATTTAAACTGGGATGACCCAGGCGAAAGCCAACAGGCATTATCAACTATACTAAACAGCCTGAATTCTGTAGAAGAATGGATGCAACAGCAGCCTAATCCTGATGAAATAGAAGAGGCGCAAGCTCCTCTCCAGGTTGCCCGATTGATTGAATCCCAAAATGTGACAGCAGACTCAATGGGAGTGCCGAAGCTGGCCAAAGGGGTGGCTAAGGACCGACGCATTTCTATTGAAGATCCAGATATGCGGCATGGACGAAAAAGCCGCTCTCAAAAAATAAATGGTTATAAACGCCATATTCTTAAAGATTTAGATATAGGAGTGATTCGAGCGGTGGCTGTAACCCGAGCTAATACACCAGAATCCGCTGCCACTGTTGACTTAGAACTTGACTTAAAAAGACAACAGGTTCAGTTAAATGAACTCCATATCGACCGAGCTTATTTGTCGAGTCATTGGGTAAAAGAACGCTCTGAACAATTACAAATATTTTGTAAGGCATGGCCAGTAAGAAACTCAGGACGATTTGATAAAAACGCTTTTGTTTTTGACTGGGAAAACCAGGTAATTAGTTGTCCAAATCAAGTTATTATGCCGTTTGAACCCGGTAAGGTCGTTCATTTTCCAAAACCGGACTGTGCAGTTTGTCCCCTGAGAGAACGCTGTACTACGAGTAAGAATGGCCGCAGCATATCTATCCATCCCGATGAAGGATTGATGCAGGAATTGCGTCAGCGTCAATCTACATCAAGCGGTCGCGCACAACTGAGGGAGAGAACCTCTGTAGAACATTCTCTTGCTCATGTCGGACAGTGGCAGGACAAACGCGCCCGTTATATTGGACAGCGCAAAAACCTCTTCGACCTCAGACGAGTGGCTGTTGTCCATAATCTTCATGTCATTGCTCGAATGAATGAGGTTTTACCAATACAACAGGCCGCACTGTAGTTGAATCAAGCAGGTAAATACACATTTTCTGAGTTTTGTCAAGATTTTTTACTGAACCGACGCCCTAGTCAACCACCTAAACCAAGGTCGAGATCGCATTGCTGAACCCGCCCAAGCCGAAGAACTGGCCCACCTCAACCTCAAAGCCGGTAAAAAAGCCAAAGCCTCTGCTGCCTATCAACCCGCCTTCACCTACTTGGTCCTGGGCTTGAATTTGTTAACCACAGAGTGTTGGAAATCTCAATATGAATTAACCTTAGCCCTCTATCAAGAAGCCACAGAAGCCGCTTATCTCAGCGACGATTTTCAGCGGATGGAGGAATTCGCAAATCAGGTAAAAATTCATGCTCAAAGCGTCATTGATAAAGTCCAAGTTTATCGAGCATTAGTTCTCGGCTATGCTAACCAGCAACTCCTCCCCGAAGCGATCAGAAATGGGTTAGAAATTTTACAAGACTTAGAAATTGTCCTGCCGGAACAGCCCACTCCAGCAGATATCGGCCAAGAGTTAGGAGTAACCCAAACCGCCTGGGAAGGACAGGAAATTGAGGCGTTAATCGACAGACCGGAGATGACAGACCCCTCCAAGCAAGCTGCAATGGATTTGCTATTTGATGTCATTCATCCCGCTTATGATAGCAACCCTGCCTTGTTCACCCTTTGTGCCTTAAAAATGGTGCAACTTTCTCTCCAATATGGGAATACACCTCTCTCAGCCCAGGGATATGCTTCTTACGGAATCGTGTTGTGCGGGGTCGTTTTCGATATTGATTCTGGGTATCAATTTGCTAAACTTGCCTTAAAACTGCTCGATCGCTTTCAGGTCAAGAAAATCAAATCGGCAGTGTTCTTTTTGGTTTTTTATTTTTCCATCCATTGGAAAGAACATCTCAAAGAAACATTACCTCCTTTTTTGGAAGGCTATCAAGCTGGACTGGAAAACGGAGATTTGCTATTTGCGGCTTTTAACGCTTACGGCTATTCTTCCTATTACTACTGGATCGGAAAAGAACTGCCCTTCGTCGAACGGGAGATGGCGAAATATAGCGAAGCGATCGCCCGCATCAATCAGAACCTCATTCTCAGCTATCAAAACCGCTATTGGCAAGTCATATTAAACTGGATGGGTCAGTCTGAAAATCCCTGTCTGTTAGTCGGGGAAGCCTATAACGAAACGGCCTTATTACCCATGATGATAGAAACGTCAGACCGATACGGAATCGGTGACTTACATCTGCATAAATTCATCCTTTCTTATTCCTTTGGCGAGTATGGTCAAGCCCTAGAAAATGCGGCGATCGCCGAACAATATTTAGACGCCATGATTGCCACCCCCGCTGTGGCAGAGTTTTATTTCTACCAGTCCCTCACTCACCTAGCCCTCTATCCTGACTCCCCTGAATCGGAACAACAGCATATCCTAGAAAAAGTCGCTGCCAACCAGGAAAAAATGCACCTTTGGGCAAAGCAAGCCCCCATGAACTACCAGCACAAATACGAACTCGTCGAAGCCGAACGTGCCCGGATCTCACACCAGCTTTCCGATGCCCGAAATGCCTACGATCGCGCCATTACCCTAGCCAAAGAACAAGAATACCTCAATGAAGAAGCCCTCGCTTACGAACTTGCTGCCCGATTTTATCTCTCAACCGATAACACCCACCTCGCCCGTTACTACCTCCAAGATGCTCACTACGCCTATCAACGCTGGGGTGCCATCGCCAAAGTCCAACACCTGGAAACCCGCTATCCCCAACTCCTGAACCTCCAAACCCCCAAAACCCCAGGCAGTACGATAACTCAGGGGACATTCTCCTCTACCTCCACCACAGGCAGCAGTTCCGGCGACAGCCTGGACCTCACTACGGTACTCAAAGCCTCCCAAGCGATTTCCAGCGAAATCAAACTCGATCAACTGCTGGCGCAACTCCTCAATCTCGCCATTGAAAATGCCGGGGCTCAAAAAGGCATCCTGATTTTATCCGACAATAACCAACTCAAAATCGTAGCCGCAAAACTCCCCGATACCGAAGTTCAAATCCTAGAATCCCTCCCCTTAACCACCGGCAATTTAGTTCCCCCCAGTATCATCAACTACGTCACCCGAACCCAAGAAAACGTCATCCTCGCCGACGCCACCGGAGAAGGAATCTTCACCCGTGAACCTTACATTCTCCAACAGCAACCCCAGTCAGTTCTTTGTGCGCCCATCATCAACCAAGGCAAACTAATTGGCATTCTCTACCTAGAAAACAACCTCGCCACTGGCGCATTTACCCCAGAACGAATCGAACTGTTACAAATTATTTCCGCTCAAGCCGCTATCTCCCTAGAAAATGCTCAACTTTATCGCACCTTAGAAGATAAAGTCATCGAACGCACGGCCCAACTTGCAGCAGCAAACAATGAAATCAGCGCCTTAAATGAAATGCTGAAGTCGGACAACCTCCGCATGAGTGCCGAACTCGATATCACCCGCAAACTACAACAAAAAATGCTACCTCGACCTCAAGAGTTGCAGCAGATTCCCACATTAGAAATCGCAGGATTTATGGAACCGGCAGATGAAGTGGGGGGAGATTACTACGATGTCCTCAACTATGATGGACGGGTAAAAATTGGCATCGGCGATGTCACCGGACATGGCCTAGAATCGGGGATGATTATGGTTATGGTCCAAACCGCAGTCCGAACTTTACTCGCCAATAATGAAACGGATGTTGTTAAATTTTTAAGTACCATCAACCGCACTATTTACGATAATGTCGAGCGAATGCAGTCGGATAAAAATCTGACCTTAGCCTTGCTGGATTATACCGATGGCATTCTGCGAATTAGTGGACAACATGAAGAGATTCTGATTGTTCGGGCTAATGGAGACATTGAACGAGTTGACACGGTTGATTTAGGATTTCCCATTGGATTAGTGATGGAAGTTAACGATTTTATTACCCAAACTCAAGTGCAGTTAAATCCAGGAGATGGGGCGGTTCTGTACACCGATGGAATTACGGAATCGGTCAATGTAGCGAATGAGCAATATGGATTAGAAAGACTCTGTGAGGTGGTCTCACAAAATTGGCATCGCTCTGCAAAAGAGATTCAGCAGGTGACCATTCATAACGTCCGGGAGTTTATTGGTCAGCAAAAGGTGTTTGATGATATTACGATTGTGGTCTTGAAGCAACGGTAATTTAGGAGTGGATGAGCGCACTCCTAATATTTTCTCTGTTTTCATCCTTTTGATAGAGGGAAAAACCGGATTAATTGTAGTAAAAAAGAACTCTAATCTCAACCCCAAAATTAGTTATGCAACTAACCCGCGTTGATGGGATCGCCCGAGGACTAGCTTTAGAGGCGATCGCCTCCTATAAAATTCACCTTTCTCCCAGAAAAGGTTTTGCCTGCGCTCATCGGATGTTACATCAAGATGAGTCTTGCTCTGATTATATTTACCGGATGTTTAGCAGTGAGAATTTTCTGGCTGCCGTTGCCCACTCTGGGGAACGGTTCCGCGCTTGTGCTAACGCCCACCAATCCTTAAAAGGAACCTCCAAATCTGGTTTCGGCTGTATCGTGCTTCCCTGCTGTCTCCCGTTATAATATCAAGTCCAGTGGATTAACATAAAAGACCATTTCTTCCTTCCCTCTTCTCCCCCTTCCCTCTTCTCCCCTTCCCTCTTCTCCCCCTTCCCTCTTCTCCCCCTTCCCTCTTCTCCCCCTTCCCTCTTCTCCCCCTTCCCTCTTCTCCCCCTTCCCTCTTCTCCCCCTTCCCTCTTAGGGAAGGGGGTTGGGGGGTTAGGTCAGTCTGGGTGATTGAGAAACATGATATAACCATTAAAGGTGTCAATCAGCAGGCGTAATTCGGGTAGAGGCGGGTCATTTTCCGTTTCTACCCCCTTTTGCTATTAACTGGAAGCGCTAGTATAAAACCGGAGGGCAAACCGCCAAAATGCCATCGAAGCCAAGAAGAGGGCGATCGCCAAGAGGGCAGCCCCCGCAATCCAACTCAATTCGACCCGTCCCAAAACGGACTCTGCCGGGACGGTAGTGAGAAAAGCGACGGGGACAATAAAAGTGAAGAAAAAGCGATAGGCAGTGGGATAAGCCACCATTGGAAATCGACCCGCTTCGAGTAATCCTCTGAGCACTTGAGTCACATTATAGATTTTTACAAACCAAATACTCATCGCACCTAGCATAAACCAGAGGCTATAGAGGCTGATGGACCCAAAGAGGAGGGGAATGAAACTGACAAGATAGTTAACCGGGGGTAAATTCAATTGGCTACCGGCATAAAAAATCAGGAGTAAGCCTAAAATAATATCCGGCAAACCCCAAAGGGAAATCGTCCGTCCCGAGAGCCAAAATTGAGAACTGATAGGTTTAAGCAGGACAAAATCGAGAGTGCCTTCTTGAACTTGTTTAACAATAGTATTCAGATTAGGAGCGAGGAAGGTGGAGGAAAAGCCTTGGAGAATGGTAAATACTCCTAAAACCACGAGGGCTTCTTCCCATTGCCATCCTGCGAAATTGTAGTCAGCGCCGTAAAACAGGGAGAGGGCAAACCAACTCCCTGCGAGGTTTCCGAGGCTGCTGAAGGCGGCGATCGCAAAATTGACCCGATATTCGAGCTCAGCGGCGATCGCAGTTTTCCAAAATAGGGCGAGTGTGGACAAATATCGGTTCATTTCCAGTAGGGACTTGAGAGGAGCAATGGGGACAGGTCAAAATTAGTCGGTGTTTTTATTAGCGTAGCGCAGCGATCGCCCATTGAGGAAAGTCGCAAGAATTTAGGGACCGGGATTGGGTAACCAAGGTCAATTTGGCTGGAGTTAAGGTAAGCTAAGGAAATCAGGCGATCACCAATTGAGGGCATTCAAAAATCAATGAACGAATTTACAAAAATATTACGCGATAAAAAAGCCACGATTGTTGAACAATGGATTGCATTGGTTCGGGAGGATGAAAATATTAGTACAGCAGATAAACTCCCCTATGCTGCGATTCGCGATACTCTGCCTAACATCATTGATGCGATCGCTTCTCTTCTTGACCCGCCCGAAGAAGGCGAGGAGGCGGATCTGTTACAATCGGCCTTAGAACATGGCTATATTAGAGCGCAACAAGGCTACGAACCTCAAGAAATTGCCCGAGAATATGGGTTAGCCCGAGAGATGATGCTTTCCGCGATCGAGGAGGAACTGGAACGAGCCAAACCCCAGGTAATTATTGGTGTCATCCGCCTGATTGATAAGGCAATGGATAAAGTCATCGGACGCTGTTTCCACAGTTACACAGAAGAAAGATTGCAAGAGTTGGAAAATTTGCAAAGCCAACTCCATTTCACCAATCAAGAACTCAGCCGATTAGTCCGGACGAGTAAAGAAAATTTGGCTCACCTCGCCCACGAATTAAAAACACCATTAAATTCGATTATTGGCTACTCGGATTTGTTTTTACGCCAACAGCGAAAGCATTTCTCTGAAATTAACGACTCTACACCCAACATGGAACATATAGAAAGAGTCCTTCGCAGCGGAAGACAGTTACTACAATTAATTAATGATACTTTGGAAATTTCCCGTTATGATTCAGGAAAAATGCCCTTAAATTTAATAGAAATTCCCCCTAAAAATTTAATTTGCCAAACGGCAGAAATGTTAGAGACAATGGCCCGAGAGAAACAGATTAACCTAGAGGTGAATTGTGACCAAGCTCCCGAGCTAATCGTTACGGACCCGTTACGGTTACAGCAAGTGGTGACTAATTTGCTGAGTAATGCAGTTCGCTATACCCCAGAAGGAACTGTCAGAATTGAGTGCCGAATTAGTTCTAAACAGGAGTGGCAAATCGTGATTAGCGATACAGGAGTGGGAATTGATGAAAAAGACCAAGCGGAGATTTTCAACCCGTATTATAGAGTGATGAGTGAACATCAGACTGTTCTTCCCAATAGTACAGGATTGGGACTGGCGATCGTGTCTCGTTTGGTTAAGTTGTTGCAAGGTAAAATTGAGGTTGTTTCACAATTGAATGTGGGGTCTACCTTTACGGTGACTTTCCCCCTCCAAATCCAGTCCTCTTAACCTTCCAAAGCAACGCTAAATTCTCAACTTTATTTTATTTTCATCAACCGAGACTTAAACCCTTTCTAGGGAGTTCCTAAAGTTTTGAGTTCAAATCAAGCCCCCATCCCGGAATATTGGCGCAACCCGCGACGCCACAACCAGCGATTGATGATCCAAAAGATTGCTATCCAACTGCACATGATGGCAAGACTAGGGAGAACATCCACAGGTAATCCCACCAATAGCGCTGCTGGAAAGTGAATCATATAGGGAAACGGGGTCCATAAAACCACTTGGCGCACTGATTCGGGGAACACCTCTAAGGGAGCAACCATTCCGGAGAAAAAGAGATAAAATAGAAACCAAAATTGCTCGATCGCATTCGCCCGTTCTATCCAAAAACACAGGAGAGAAAAGGTATATTGAATCAAAAATCGCAGGATAAATCCCAGAATAACTACCCCAATCCACAGCAAAAACCGTCCTAAATTAGGCAGCCAAAATGCATCGGGATATAAGGCAAAAAAGATTAAAATCAAACCAGCAATAAAGGGGAGACGAGCACCACGTTCTGCTAAATGAGCGGCGACATGATGCCACACCGGGTCCAAGGGTTGTAATAACCGCATGGAGAGTTTTCCTTCCACCACTTCTTTTTCAAACTCCCAAACCACCCAAACCACATTGAATTGACGGACAATAAACGCCGCTAAAAAATACCGAGCAAATTCCACGGGGTTTAAGGCAAAACTTCCAGTTTGAGAGGCTTCTAACCAGAGTCCCATTAAAATAAACGGCAAAGTACCCGACAGCGCCCATAACACAATTTCGGCGCGGTATTCCAGCATATAAGCATAATGAACGGAGAATAAGGTGGGAGCAATTCTGAAAAAACGTCTCATGAATTTTAGGGGTTAACAGATTAGGGTATGGGTCCAGGGAAAGGGTTGAGAAACCGGATTTATTAACACAATTTCGGGGATTTCTATAAACTTGGATTAAAAACCCGGTTTCTGGTCCTCACCGAATGATTTAGGCGATCGTCCCAGCGGTAAAGACTCGTCCAATCACTTCTTCAATCGGGGGTTCAGTCACCGTCAAATCTAGTATTTCAAAATCGATTAAAATCTGACTCACCGTAGCGGTTAGCGTATCCCGACGCACCAGTAATCGCACCGACTGACCCGCAATTTCTTCGACTTCGCCATACTGCGAGATTTGTTGTCGCAATTTTTCCGGGTCAGCAATCGCCTGAGTTAACTCTAACTGCACCTCACGATAGGGCGCAAACCGCTCAACTAAGCCATCTAAACTGCCATCATAAATCAGTTGACCTGCATAAATTAAAATCACGCGATCGCAAAGGGCAGTAATATCCGCCATGTAATGACTCGTTAACAAAATCGTCGCCCCTGTGCGTTGATTGTATTCGCGTAAAAACTCCCGGACTGATGCTTGTCCATTCACATCTAATCCCAGGGTCGGTTCATCCAAAAATAAAACATCAGGATTGTGCAATAATGCCGCCATCAATTCCGCTTTCATCCGTTCCCCGAGGGACAGCTTTCGGACAGGTTGATTGAGCTTTCCTTCCAGAGACAGCATTTCCGTTAATTGACCAATCCGTTCCCGACATTCTTTCTCGGGAATTCCATACACCACCCCATTAATTCGCAAGGAATCTAAGGCGGGTAAATCCCAGAGTAACTGTTGCTTTTGTCCCATGACTAAGGTAATTTTTTGCAGAAACGCTTCTTTGCGTTGAAAAGGAACATGACCCGCCACCTCCACCCGTCCACTAGAGGGATGAATTAGCCCGGTTAACATTTTTAAAGTGGTGGTTTTTCCGGCCCCATTAGGTCCTAGAAATCCCACGACTTCCCCGGGTTGGATTTGAAACGAAACATCTTTTACCGCTTCGATATTCCGATAGGTCCGTTTGAAAAAGTGATTGAGAGTCCCTTTCATTCCCGGTTGTTTGATGGCAACGGGATAAACTTTACTGAGATGTTCGGCAACAATGATTGACATAATAATTATTTTTACTAAAACCGCAACTCATCCGGTGCAATGTTCATCGAACCCCGCCGAGGTAGACTGGGTTGGAGTAGCCCCATGCTTTAGGGCTTTAGGGGATAGGTTTATTTTAGCTCAGGGGAGCAACTCTTTTAAATTTACAACGCGAACCACGGGATTGCGATGGGTAAAAATCAACCCATTATGACGATAAACGAGAATCAATTGGACAACCAGACGCTCAATAATTTCGATGATTCGACCTAAACAATGGCGACTTTTAAAATGTTCCAGTGGGGAGGGAGTCCGCTGAATCAACCATTCGGTGAATCGGTATTTCCAGGACCGAGTTCCCCGTTTAGAGATTTGTAAAATTGTCCCGGGAATGAATTCCCCTTGATTGGCCCAAAATGCATAGCGTTCCCCGAGGGTAAAGTAATGAAATACTGAGGGATGGGGGCTAGATTGGGCTAACTTTCGGGCAACTCCTAATGGATTAAAGGTGACGACGGACCGAATGCGATCGCCGTATTTAACCCCCAGTTGCTGGGCAATTTTGCCGCCAAGACTTTCGCCAATCACGTCCGGGCGATCGCCCTGTTGATATTTTTCCGTAATCCAAGCGACTGCACCTTGGGTTTCCGCCGCTTTCGATTGCCAATCAAGATGAGCAATAAACACCTCTGGCGTATCTTGAAGGACCCCATCCAACGGATACCAAGACCCATATCCCCGAATCACTAATACCGGCGGTACATTCCCCAATAAAGGAATCCGACCCTCGGCATAAAATCCTGTAATTTTATCTTCAAATACTTTTTCTACCTGATAGTTTCCTCGGACAACTTGGCCCTCGGTATGACGGACATAAATCGAGGGTTCATCTTTTTTTAAAATTAAGGTCAGTTGGGGTTTACTAAACTGTTCATAAATCACATCTAGAGGATGGCGAGGGGGTGGGGACGGGATGAAATCCGGGAAATTAACTGAACCAGCGGGTTTTTGACCGAGTTGAGCACGTTTTGAGTTGGATTTTTTGCGTTTAGATAGCACGAATTCGTTCCCCTGGCATACGGAGTAAAAACCCGCAGGCTGAAGCCTGGGGCTACACGGACGAAGCCTGCCTTCGCAGGCTGAAGAGTAAAATAGGTCGAGTACAACGGGATTTGGTATCATACCAAATCCGGGTATAAAAAATTGTTGTTATAGAGTAGCCCGCGCAGGCGGGCTTTGTCCGTATAGCCTCCGGGCTTCAGCCTGCGGGCCCCCAGTTTAGGGAAAAATTTCCCCCGCTTTCACCGTGAGAATTTGAGCAGAATTGATCCAATCATGTTCAAATCCGCCTAAATGAGTTGTCGCAATTACGGTTTGAAATCGGTCTTGAATCGCTTCAAGCAGTTGGTTTTGTCGCTTGGGGTCTAACTCGGCCAGCACATCATCAAGGAGTAAAACAGGCGGTTCTCCAACGATTTCCTCAATCAGTTTGAGTTCTGCCAATTTTAAGGCTAAAACTAGGGTGCGTTGTTGTCCCTGGGAAGCAAATTGTTTCACGGGTAATTCATTGAGAGTGAACTCGATATCATCGCGGTGGGGACCGACCAGAGTTGTGCCTTGAAATGATTCTGCGATCGCCCGAGATTGGAGTTTTTCTAAAAATGCCTGCATTGCCTGTTGCGGACGATCGCGCAACGCTTTATCTTGCATTCCTTCCACATTTGGAGCATAATGAATACATAACGATTCCACTCGCCCACTAATCGCCGCGTGCCAGGTTTCGGCAATGGGAACCAATCGCTCTAATGCCCGCGATCGCCGCTGCATCACCCGGACTCCAATGGTCGCCAATTGAGCATCCCATAACCCCAATTGTGCCTGATGTTCCGGACCTAAATGAGATTTCTCTCCCCGTGCTTCGGCACTTCTAATCTCTTTTAATAACGCATTTCTTTGTTTTAACACTTTATTATATTGTTGTAAAATATGAGCATAAATTGGCTCCAGTTGCACCAACAATCCATCTAACCAACTGCGCCTGGTTTCCGGACCGGACCGAACTAACTCCAAATCCAAACTCGAAAACTGCACGACATTTAACAAACCCAAAAAATCGACATTCCGCCGACAGGTTTCTTCATCTACAGATACCGTTCGCCGTCCACTTCGCCGCAGAACCACTCCCAATTTAACTGACCGATATTCCCGAGACACCATCCCAATAATTTGTCCCTGGGGTTCTCCCTCCCGAACTAAATCGCGATCGCGACTGACCCGAGAACTCTTCAAAGTCGAAAGTAACCCCAACGCCTCCAAAACATTGGTTTTTCCCTGTGCATTATCCCCGACTAAAATGGTCTTCGGGGCATTTAACTCAATCTCCTGTTCTCGATAATTCCTAAATTGTCTTAAATGCAGTTGGTTTATAAACATAATTAAATCCAGCTTGTTAAAATAAAATCACACCCTAATCTCAATGAAAAATTCTCTTGTTTGTAGTAACGACTTCAGGCGTTATCCCCAGAGGGTTTTAACCCTAGCCCTGTCAAGGTGTATTTGTAGGGGCGTATTGCATACGCCCTCTCATTTATGCAATACGCCCCTACAAGAAACAAGGATGAGGCGGAATTCCATTGACGGTTAAAGAGGGCGTATGCAATACGCCCCTACAAGAAATAGCGATGAGGCGGGATTCAATTTACCATCTTGACAGGGCTAGGTTTTAACCCCCGCCGGGAACGGACTTTTTCCTCCCATAAAACAACCGAAAAAAGACCTTTTCCATCTCCACCCAAACAAACAACAATGAACTAAATCCTAAACAGATTGCCAAATCAGTCGGCGTCAACCAATGGGTTCCAAAAAACACCCTTAACGGTTCGACATAAATCAACATAAGCTGGAGAATTGTAGTGATAATCACCGCCCCGAAGACAAACGGATTCGAGAAGGGATTTAACTGAATCGTTAACTGAGTATTGGACCGGACCGCGATCGCATGACCCATCTGAGCAATACACAGGGTCGTAAACACCATTGTTTTCCAACGGTCCGGAGACAGTCCATTGCCACTAACGGTGTGCGTGTAGGAAAAGGCCACCATCATTAAGGTAATGGAAATTATCGCAAACACAATCCCAATTCGTACCATATACAACCCCAAACCCCGGGCAAAAATATTCTCCCGAGGACTAAAGGGGGGACGATTCATCACATCCGGTTCTGGGGGTTCTACTGCCAATGCTAAAGCGGGAAATCCATCGGTAACTAGATTCATCCAAAGAATTTGTAACGGGGTGAGGGGAACACCAGGTAATCCCAACAGGGGTGCAGCCGCGATCGTCAGCAGTTCCCCAATATTAGACCCGAGAATGTATTTAATAAACCGGCGAATATTAGTATAAACCACTCGACCTTCTTCCGTTGCGGCAACAATGGTGGCAAAATTATCATCTAGCAGGACCATATCGCTGGCCTCTTTACTCACATCAGTTCCCGTAATTCCCATTGCAATCCCGATATCCGCTTGTTTGAGGGCCGGTGCATCGTTTACCCCGTCCCCGGTCATGGCGACAAATTTACCCCGTTTTTGCAACGCTTGGACGATTCTGAGCTTATGTTCCGGAGAGACTCGGGCATATACACTAACGTGATCGACCTGATACATTTACGCGACATTTTTCCGGTTGTTCCCGGACAATGCGACGATAGCACTATTACCCGTTAAGGTAACAGAGGCGGTATCCCGCAAAGCTTTTAGAAAGATTCCAAAAGCACCGTTCCAGTCCCTGGGTAGAGTGACCCCACACTCGGGACATCGGAACACTTTTGAGCCACCTAGCTTAGAGTGAACATGACCACAGTGAGTACAGGTTTTACTGGTGTATTCTTCGGTCACATCCACAACGGTGGTTCCAGTTATTTCGGCTTGATGTTTCAGGGTTAGTTTGAATCGATAATGCGCCCAGGTTAGCATTGCCCTTGCTGTCTTAGACCTAATTTTCCGCTTGGCCTTGGCAACCATGTTGGAAGTCTCGAAGGTAGGCAGAAAAATCACACTATAGTTACGAGTCAAGTAATGAGCAATTTGTTTGTGGGCCTCATCCACCAAATTCCGGATTTTGGTTCTCATTCGTTGAGCCGCTTGCTTCATTCTCCGTCGCTTTGAGCGATTGGGCTCTTTAGCGATTCGGCCCATCAAATCATCCAAATGTTGGCATAGCCGAGTAATACGTCCTATATCTCCGGAGCCAAATTCTAAAAATCGTGAACCATCAAACCCAGTTATGAAAGTTCGGACACCCGGATCTAATGCAATCACTCCGGTGGCTTCCGTTGGGATAAAGGCAACAGGTTCAGGGAAAACCGCAAACCATCGACCTTTGGTAAACACCAACTGAGTTCCTTGGTCGCAAGTTTTAGGGATAGGTTCGGAAACCCTGAAAGTTAATCCTTTCGTCAGTCTTGGATACCAACTCCCTGAAGAGAAATTAGCATCGTTAAACTTAATGGCTTGGGAACTGTCACGGCAACTTCTAAACCTGGCGTCAGAACTGGCGCTAAAAGCCAGATGGGCATCGAAGATTGCATTTTGCCGGATGTGACAAGGCGTTTCTTTAACCCACGCAGGCAAATCACTCTGCATCACTTCGTTGCGTAACTTCAGCTTGCTTAGTCGTTTACCGCTTTTCTGCAAAGCAATTGCTTGGTTGTAGCAATACCGACAAGCCGCCAGCCATTTGCGCCAGACTTTATTTAGCTCGGGGCTGGGGTAAATCTGGATCTTCTTTGACCTGAGTTTTGTATTTACGCAGTCCGTATAATCGGGAGCTAAAGCAGTGGAGGATGGCGAGAATGTCCTCAACCATTTCTCGTTCTGGACTGAGACTTGTCTCATTGAGAACCAAGAGTTCGCACCTGTTTTGCTCACAGAGCCATCGAAACAAGTCAAATCCAAATCTGGCCAATCGGTCTTTGTGGGCAACGACAACCATGCGGACATCTCCTGACAAGACTTGTCCCAGTAAGGCCAGCATTTTCTTTCGCTTGAAGTTGAGCCCGCCTCCGATTTCTGAGACGACTTCTGCTTCGGGGTAGAGGTTGGACAGTGCGGCAACCTGTCGGTTGAGGTCGGACTGCTGGGCGCGGCTACTAACTCTGGCATAGATAACGACTTTGCGTTTGTCACTGCCTGAGAAGGCAGTATATGACTCAACGTTGTATCGTCGTTGCCCAGCGGGGGTTCTGATGGTCTCGATTGAGCCATTTTCGTCCCATCTGCGGAGTGTTCTTTCATGGACTCCAAGGATTTGGGCCGCTTCCTTGGGCTTGACATATCTGGCAAT

Protein sequences of DBSCAN-SWA_4

>NC_019693|6607210:6661213|6643572_6644085_-|WP_052315802.1|DBSCAN-SWA
MTILFFGNPLMVNEETDYVKFLTTVNRTIFDNVVRMRSEKNLTLALLDYSDRTLTISGQHEEVLVVRTGGTVEQIDTMDLGFLIGLDTEIADFISQIQIELNPGDAVVLYTDGITEAENLDGEQYGLERLCQIIGENWQLSPEEMRAAAIADLRRHIGEQKVFDDKLSYI
>NC_019693|6607210:6661213|6625510_6626416_-|WP_044197962.1|DBSCAN-SWA
MTTQQLRLPTAIAKETWIWNGHKVQYAVQGVGRPLLLIHGFGASIGHWRKNIPALAEGGYRVFALDLLGFGGSDKAPLNYTLELWEELITDFWTEHIQEPTVFIGNSIGALLSLMLVANHPEKSAGGVLINCAGGLNHRPEELNPPLRLVMGTFSKLVSSPTVGTFLFNRIRQKHRIRNTLRQVYRNREAITDELVDLLYEPSCDVGAQKVFASILTAPPGTPPSEILPNVTHPLLVLWGEDDPWTPIAGSRIFQQSHPDRTITFKSIPNTGHCPHDERPEVVNPLILDWLKTSLSGNSNP
>NC_019693|6607210:6661213|6621678_6622509_+|WP_015151309.1|DBSCAN-SWA
MAIDNLCKYLATKYPQRFASWILRRIITSPVEVLKTELTLEPVRADSVIFLRTNREILHLEFQIKVPTDRPMLLRMLNYWVRLYWQYGLPVRQVIIWLQPTSNPAVFETEFVSENTRHRYEVIRIWEESPELLLQDPALLPLAVLAATQEPNQLLAQVAQELAKIEETELRQEIAACTQVLAGLRFNKDTIANFFREEIMQESVIYQDILQKGLNQGKKQEAIALIQGMLNRRFGSLEPNVQERLQSLTLTQLEELSLALFDFTEVTDLVTWLQSR
>NC_019693|6607210:6661213|6620776_6621607_+|WP_015151308.1|DBSCAN-SWA
MAIDNLCKYLATKYPQRFAAWILRRIITSPVEVLKTELTLEPVRADSVIFLRTNREILHLEFQIKVPTDRPMPLRMLNYWVRLYWQYGLPVRQVIIWLQPTSNPAVFETEFVSENTRHRYEVIRIWEESPELLLQDPALLPLAVLAATQEPNQLLAQVAQELAKIEETELRQEIAACTQVLAGLRFNKDTIANFFREEIMQESVIYQDILQKGLNQGKKQEAIAMIMRPITRRFGSLAPDIRERIDALTTAQLEDLNEVLFDFTEVTDLVTWLQSR
>NC_019693|6607210:6661213|6653971_6654760_-|WP_015151327.1|DBSCAN-SWA
MRRFFRIAPTLFSVHYAYMLEYRAEIVLWALSGTLPFILMGLWLEASQTGSFALNPVEFARYFLAAFIVRQFNVVWVVWEFEKEVVEGKLSMRLLQPLDPVWHHVAAHLAERGARLPFIAGLILIFFALYPDAFWLPNLGRFLLWIGVVILGFILRFLIQYTFSLLCFWIERANAIEQFWFLFYLFFSGMVAPLEVFPESVRQVVLWTPFPYMIHFPAALLVGLPVDVLPSLAIMCSWIAIFWIINRWLWRRGLRQYSGMGA
>NC_019693|6607210:6661213|6616073_6617246_+|WP_015151305.1|DBSCAN-SWA
MQFANRLEPLRSNVFADMDNAKAKAKAAGLKVIDLSLGSSDLPPAPHIIEAIASSLPDRNSHGYVLFHRTQAFREAAARWYHQRYGIAVDPQTEVLALIGSQEGTAHLPLAILNPGDFALLMDPGYPSHAGGVYLASGQIYGMPLREENGFLPVFEEIPQGVLNQARMMVLSYPHNPTTAIAPLSFFQEAVAFCQQHQLVLIHDFPYADLVFDAQISVPSVLQADPEKTVSIEFFTLSKSYNMGGLRVGYAIGNPELIKALRQVKAAVDFNQYQGILNGAIAALTGPQDTVGEMTSIFRNRRDAFVNALHRIGWQVPMPESTMYVWAKLPEQWANNSIGFCTQMVEKTGIAASPGSGFGKMGQGYVRFALVWDPPVLEEAVERIAQFLNS
>NC_019693|6607210:6661213|6634411_6635482_-|WP_015147826.1|transposase|DBSCAN-SWA
MGARLRVFLTPEEDRTLFELRMATTLPQRVKDRASIVRLNAHGWYVEKIASHFNWSVSRVRDTLHRWEKKGLGGLWDKAGRGSKAKWQDADIAYVEECLRQEPRTYNSKQLAKKLAAERQVYLSPDRLRRVLKKKGIIWKRTRISHKNKQDPEERSIKQADLDMLEFAAAAREIDLKYLDESGFCLWSSVGYTYFPKKEQKCQEQTRIRGRRLSILGIMQPKIGFTYGLAIGSFTSKSYIKMMEIEAEEASKELALTGRIRVIVQDNGPIHKSLEVQNKWPSWEEKGLYIFLLPKYCSEMNEIELEWQHLKRDELAGRMFEDELDLAYAVMAGVEARSVEGNYTAKRVKFKSGPSP
>NC_019693|6607210:6661213|6657146_6658301_-|WP_015151330.1|DBSCAN-SWA
MFINQLHLRQFRNYREQEIELNAPKTILVGDNAQGKTNVLEALGLLSTLKSSRVSRDRDLVREGEPQGQIIGMVSREYRSVKLGVVLRRSGRRTVSVDEETCRRNVDFLGLLNVVQFSSLDLELVRSGPETRRSWLDGLLVQLEPIYAHILQQYNKVLKQRNALLKEIRSAEARGEKSHLGPEHQAQLGLWDAQLATIGVRVMQRRSRALERLVPIAETWHAAISGRVESLCIHYAPNVEGMQDKALRDRPQQAMQAFLEKLQSRAIAESFQGTTLVGPHRDDIEFTLNELPVKQFASQGQQRTLVLALKLAELKLIEEIVGEPPVLLLDDVLAELDPKRQNQLLEAIQDRFQTVIATTHLGGFEHDWINSAQILTVKAGEIFP
>NC_019693|6607210:6661213|6624799_6625399_-|WP_015151312.1|DBSCAN-SWA
MSYHYILFYKPYDVLCQFSDRDGKNAGIQRPTLKDYIDIPDIYAVGRLDLDSEGLLLLTNHGAIQHRLCSPKYAHPRTYWVQVERIPDEQALDSLRNGVQIQNYRTRPATVQLLPTEPELPPRDPPVRFRKTVPTAWLEITLTEGKNRQVRRMTASVGFPTLRLVRSRIGNLSLAGLQPGQWRDLTPEEVKSLLKQLRS
>NC_019693|6607210:6661213|6607210_6610069_-|WP_015151301.1|protease|DBSCAN-SWA
MSKAKRLLILFLAFFILPVTFGLFSGQANSQMPEPRYYSQNIPVPTPDEWEDKNGDNEDAENSEESEEDDSDSLQKFDEVVKDAENLPGLFTLYHNKKTGKVYLEIQPEQLDTNFLAVMTLASGIGEGGLFRGMPLQDFLFFFKRVNKNIHFGVRNVYFRASPGDPVERSLNRSFSDSVLASLPIESIHPDRESLLIDLNKLLIDRQDITGLTSILPWLLGTAYSRDSDKSYFGRVQTFPSNVEIESVYGFSGGDDLFSTVQSLPDSRGFSLNVNYSLSALPVNNGFRPRLADNRVGYFITAYQDLSNDRSREPFQRYINRWHLEKENPDAPLSPPKQPIVFWIENNVPVEYRDALREGIEVWNQAFEKAGFSNAIEARQMPDNAEWDPSDVRYNTIRWSSSFESWFAGVGPSRVNPLTGEILDADILIDGNIVRSIKNEYRTLVQQQPNASEMTFLGKMLQGTPCFPGMSSNSGMGNSEGMMGNSGPSVQQPPQVHSFVRKMMERYDLCYGMEAPQQLAIGAMGLSMLHNAFPSGEEMTNYINQYLTFLTAHEVGHTLGLRHNFHGSTMLSPEELHNTAITRTEGMVASVMDYVPVNLAPSDQKQGDFFPMLVGPYDEWAIEYGYKPLPGMLPQQEQRELQRIAAESSTNPDLAYAPDEDSMDILNPAANMFDLSGDMLQYSEWQLENAREMWERLDTRYPVSGESFTEVRQMFDTVFSYYFRQAMNATLYIGGQWFNRNHADANGRLPFEPVSVEKQRQSLALLQKYIFDETALRFPPQLLNKLAPDRWYHWGAVPVVYPLDYPIHQRINLLQRVVLRELFSYPRLIRLQDLELKTEPGQALTMQELFDTLEGGIWTEVIDSPDDLNVISSVRRSLQREHLGMLIGMVLRSTSVPDEARTLARYNLRQLQGEVDNTLKRRGRHLDTASKAHLEETRDRIDKTLEAQFQSG
>NC_019693|6607210:6661213|6635678_6636782_-|WP_015151317.1|DBSCAN-SWA
MFDRYQIIDADCHVLEPIEMWQEYLEPAFKHRAPSPKMEIDGEKIYFKISEELQQAGLSAILRDLHSYGISRYDSASQVQAVKAMGVEFCFLYPTMGLWLFAVDTMAPQLAGAFTRAYNNWLRDFCSYDPHILRGVGAISLHDPEEMVSEVQRIAEFGWKAVFLRPNPVKGRLLSDPAYEPFWAACEQLGIAVGIHEGTHSRLPATGADRFNTRFALHACSHPMEQMMAMLALIEGGVLERHPGLRVAFLESGCGWLPYWLWRLDEEYELFGWEVKENVKMKPSEYFRRQCFISVEPSEPYLEQAIDCIGADNLLFSSDFPHMDHRPEAIADLIAQSDRLGDGTLQKIFWDNPSRFYGLNISSPVAV
>NC_019693|6607210:6661213|6640738_6642211_+|WP_015151321.1|DBSCAN-SWA
MSVDLTQTHIDPQDPIYQPLLEDLQANILKSHDRDYSAHLFLQFKPNPDAVRQWIARFAKDRIVSAKQQLKRYNDLKTTSRSESSQLFVNFLLTYPGYQSLGFNLTAGQLREFPSPAFKVGLAHFQTILDDPPVDAWEEGFQREIHGVVMLADNNWENLQTQAQQILTELEEIAEIVNTEVGRVLRNSKGDAIEHFGFRDGVSQPLFFQPDLDDVAKQQGIDKWDPSAPLELVLVKDPLGEGDYSFGSYCVYRKLEQEVSNFKAAEKALAKALKLSKEEEERAGALVVGRFRDGTPLSLANAAQNADPVPNNFNYDDDLRGVKCPFHAHIRKANPRGDKNDLHQTLEEQRQHRIVRRAISYGELPIARDKSLSVRSRFEGQLAHLKDMTRHPIADEKVGLLFLCFQGDIFNQFMFMQKNWSNNQHFVSYTTGFDALVGQGNPKNLQQKWPQSWGKEGAIDFDFYHFVKMKGGQYFFAPSISFLKTIDSQK
>NC_019693|6607210:6661213|6656009_6656843_-|WP_044197974.1|DBSCAN-SWA
MPSPPPRHPLDVIYEQFSKPQLTLILKKDEPSIYVRHTEGQVVRGNYQVEKVFEDKITGFYAEGRIPLLGNVPPVLVIRGYGSWYPLDGVLQDTPEVFIAHLDWQSKAAETQGAVAWITEKYQQGDRPDVIGESLGGKIAQQLGVKYGDRIRSVVTFNPLGVARKLAQSSPHPSVFHYFTLGERYAFWANQGEFIPGTILQISKRGTRSWKYRFTEWLIQRTPSPLEHFKSRHCLGRIIEIIERLVVQLILVYRHNGLIFTHRNPVVRVVNLKELLP
>NC_019693|6607210:6661213|6645374_6645791_-|WP_044197969.1|transposase|DBSCAN-SWA
MSQIAIVQAFADLEDCRRQAGTRHKQSLCLALFTLGVAAGNRGFIAIGDWLKAYHDELLELFKPEKNRLPSYSTIRRTLLRIEQQRYSACLSRFFGIDPIESETIAVDGKVLLWYYEAINDEANVDSHPAIMLGSPKK
>NC_019693|6607210:6661213|6660619_6661213_-|WP_015150029.1|transposase|DBSCAN-SWA
MARYVKPKEAAQILGVHERTLRRWDENGSIETIRTPAGQRRYNVESYTAFSGSDKRKVVIYARVSSRAQQSDLNRQVAALSNLYPEAEVVSEIGGGLNFKRKKMLALLGQVLSGDVRMVVVAHKDRLARFGFDLFRWLCEQNRCELLVLNETSLSPEREMVEDILAILHCFSSRLYGLRKYKTQVKEDPDLPQPRAK
>NC_019693|6607210:6661213|6654890_6655889_-|WP_015151328.1|DBSCAN-SWA
MSIIVAEHLSKVYPVAIKQPGMKGTLNHFFKRTYRNIEAVKDVSFQIQPGEVVGFLGPNGAGKTTTLKMLTGLIHPSSGRVEVAGHVPFQRKEAFLQKITLVMGQKQQLLWDLPALDSLRINGVVYGIPEKECRERIGQLTEMLSLEGKLNQPVRKLSLGERMKAELMAALLHNPDVLFLDEPTLGLDVNGQASVREFLREYNQRTGATILLTSHYMADITALCDRVILIYAGQLIYDGSLDGLVERFAPYREVQLELTQAIADPEKLRQQISQYGEVEEIAGQSVRLLVRRDTLTATVSQILIDFEILDLTVTEPPIEEVIGRVFTAGTIA
>NC_019693|6607210:6661213|6636794_6639050_-|WP_015151318.1|DBSCAN-SWA
MLKKPMFKPQFRCETMPLEGVFLLSETDRFLLRGTPYTLLAPLLNGNYTVTEIVDRLQDRLSVFEIYTLLDRLKELGYIIESTDSIPEDRAAFYQIQGIEPAIATHRLQEIALSILSYGNIDPHPFATQLDSLGINCSDEGTFAVALTDDYLQTGLDACNRDAIQRDRPWMLVKPVGVELWIGPIFIPGKTGCWHCLAHYLRGHRPLERYLQEHHQTENCLPTAVAAIPATVQTALSIAATEIAKWAIASQHSRLEGQILTLNTLTWEQRYHKLWQRPQCPCCGNPESLTIAHFAPIVLQSRPKSFTRDGGHRSHSPDYTYNTLADRISPICGAIATLQRISTWETPDGLTHSYRAQYPTVGTFPDLHHLQEGLRTEAYGKGRQDIQAKVSALCEAIERYAGTFQGDEPRICSTLSNLDNGIHPNACMQFSARQFQNRTQLNGDRITFDWIPEPLDENAEIEWTPAWSLTHNQLRYLPTAYCYSGYSQQHQAYFTRADSNGCAAGNNLEEAILQGFLELVERDSIALWWYNRLRKPAVELSSFDEPYFDRLQEYYRTLNRDLWVLDLTADLQIPTFAAISPRRDRHPENILLGFGAHFDPRLALLRALTELNQSLPAAFYGILDATTAYRDRDREGIDWWETATLANHPYLLPDSNQAPKTRPDYPHCWSDDLHTDILACVERVRAKGMETLVVNQTRPDLSLSVVKVVVPGLRHFWPRFASGRLYDVPDQMGWVSEPLTEAQLNPLPAFF
>NC_019693|6607210:6661213|6614098_6614995_-|WP_015151303.1|DBSCAN-SWA
MVDQLIRATAADGGIRAVGVITTRLTEEARQRHGLSYVATAALGRTLSSGLLLASSMKRPGSRVNIRVKGNGPLGGILVDAGLDGTVRGYVENPEIELPPNAIGKLDVGGAVGNDGYLYIVRDVGYGYPYSSTVELVSGEIGDDIAHYLVTSEQTPSALVVGVFVEAAGVQASGGILLQVMPKAATDDELVALLESRVASLSGFTPLLQAGKTLPDIFEQLLGDMGLNILPERQLVRFHCGCSHQRMLGALKLLGEEELLDMIEKDDGAEAICHFCGEVYTASRDQLTELIGTLQAES
>NC_019693|6607210:6661213|6622609_6622891_+|WP_015151310.1|DBSCAN-SWA
MQESVIYQDILQKGLAKGLQQGLQQGLQQGLNQGKKQEAIAMIQGMLNRRFGSLKLDVQNRLESLTLTQLEELSLALLDFTEVTDLVTWLESR
>NC_019693|6607210:6661213|6640067_6640391_-|WP_015151320.1|DBSCAN-SWA
MDKTPYPPDLAHAWSRLFGYAWIPENREFLQGLRKDPKVTITNVMNSGTPESIQGPCATILEYVNNDNCEYGYISIPTLPEGLKGLSEEQLYLYANQSELYGIMRQS
>NC_019693|6607210:6661213|6651096_6651390_+|WP_015151324.1|DBSCAN-SWA
MQLTRVDGIARGLALEAIASYKIHLSPRKGFACAHRMLHQDESCSDYIYRMFSSENFLAAVAHSGERFRACANAHQSLKGTSKSGFGCIVLPCCLPL
>NC_019693|6607210:6661213|6647884_6650980_+|WP_083896824.1|DBSCAN-SWA
MAEPAQAEELAHLNLKAGKKAKASAAYQPAFTYLVLGLNLLTTECWKSQYELTLALYQEATEAAYLSDDFQRMEEFANQVKIHAQSVIDKVQVYRALVLGYANQQLLPEAIRNGLEILQDLEIVLPEQPTPADIGQELGVTQTAWEGQEIEALIDRPEMTDPSKQAAMDLLFDVIHPAYDSNPALFTLCALKMVQLSLQYGNTPLSAQGYASYGIVLCGVVFDIDSGYQFAKLALKLLDRFQVKKIKSAVFFLVFYFSIHWKEHLKETLPPFLEGYQAGLENGDLLFAAFNAYGYSSYYYWIGKELPFVEREMAKYSEAIARINQNLILSYQNRYWQVILNWMGQSENPCLLVGEAYNETALLPMMIETSDRYGIGDLHLHKFILSYSFGEYGQALENAAIAEQYLDAMIATPAVAEFYFYQSLTHLALYPDSPESEQQHILEKVAANQEKMHLWAKQAPMNYQHKYELVEAERARISHQLSDARNAYDRAITLAKEQEYLNEEALAYELAARFYLSTDNTHLARYYLQDAHYAYQRWGAIAKVQHLETRYPQLLNLQTPKTPGSTITQGTFSSTSTTGSSSGDSLDLTTVLKASQAISSEIKLDQLLAQLLNLAIENAGAQKGILILSDNNQLKIVAAKLPDTEVQILESLPLTTGNLVPPSIINYVTRTQENVILADATGEGIFTREPYILQQQPQSVLCAPIINQGKLIGILYLENNLATGAFTPERIELLQIISAQAAISLENAQLYRTLEDKVIERTAQLAAANNEISALNEMLKSDNLRMSAELDITRKLQQKMLPRPQELQQIPTLEIAGFMEPADEVGGDYYDVLNYDGRVKIGIGDVTGHGLESGMIMVMVQTAVRTLLANNETDVVKFLSTINRTIYDNVERMQSDKNLTLALLDYTDGILRISGQHEEILIVRANGDIERVDTVDLGFPIGLVMEVNDFITQTQVQLNPGDGAVLYTDGITESVNVANEQYGLERLCEVVSQNWHRSAKEIQQVTIHNVREFIGQQKVFDDITIVVLKQR
>NC_019693|6607210:6661213|6642463_6643570_+|WP_015151322.1|transposase|DBSCAN-SWA
MPAPNHLSESQQEILLNELRENDSPLIRDRILILLLINDGKTYEQVAKFLQISYPTVAYWVKHGDPDKLESFKDGRAEGNHKKATKEYIDMLLDIIDKEPSKFGYEFGRWTSARLAKHLEKETGIHLSESQVRRILKSKKYVFLWAKYSLEDRQNPLKRKAFKNRLKEYLKIAKRYPKRLQVWFWDETGFSLRIVRRKQWTKRGKRKTVRGDRRKGRINVMGCLRATDKKRINFFVETGCGESFYESLKSFYALVIQEWVEQGNSEEDFLEKGPKIVIILDNASFHKRKDIAKLATEEMPKIFLEYLPEYSPDYNLIELVWHSAKEYIANKLFESISELESILHRLLNEGELIINWGRKIKNKGNQVY
>NC_019693|6607210:6661213|6632243_6634292_-|WP_015151316.1|DBSCAN-SWA
MTTEKTSQPIAPKCLHVLSCHGDERIDNYFWMHDRNDPQLIAYLQAENHYTDLMMQHTKGLQERLYDEMSDRIEEAELSVPYRQGEFYYYWRTEAGKNYPIFCRKQSSLDNREEVLLDCNELARGHRYFRLDLCEVSPNHQTLAYSIDTDGDENYTLCFLNLVEGDRYAQSIPGVCSFVWKNDSQTCFYTQVDATSRSDKLFRYTVGNPISDRILIYQEFDETFNVFVSKTRSQSYILMEVISLLTSEIYYLENDNMNGKFKLIHPRSVEVRYKLEHHGDRFYILTNEEAINGKLMQTLVDSPSRENWQTLIPEREGVNLEEISAFADRLVIYEREAGVKKVRICQLSTGEEHWIEFPESVYEIKEDKNPEFNTENLRLEYKSLVTPDSIFEYNMSFRELTLKKQTTVPNGYDRTEYVSERIWAIAPDNEAIPISLVYKRGIEKNGKAPLLLVGYGAYGVCEYISFCANRLSLLNRGVVFAIAHVRGGGEMGEKWHKDGKFLHRKNTFTDFIACAEYLIKNKWTSQEKLAIFGESAGGLLIGAVLNMRPDLCKIAIAKTPFVDPLTSILDTTLPMSVADWEEWGNPNNKIYYDYIKSYSPYDNVKQQEYPHLLITTGLNDANVPYWQPVKWTAKLREHKTDDNIVSLKINEGAGHRGASGRYEKLKEVAFEYAFLADKWGLS
>NC_019693|6607210:6661213|6611145_6613455_-|WP_015151302.1|DBSCAN-SWA
MTKDRKFPEQWPNAQPSESGQPDSSAKMPASSLSGFGRSAAGAGSQQGSGLHLPSSRSDVFSTGGATDRPGSGNQKHFGQSKKADLMLNPQIRDSRSSNRRLHGWLKWLTNWQLWALVTFLLTGGLGGTALLILLRLPATPTCEESTWTSASEHLYCAQQAARDQTVEGLLRAIAQVHQLPEDHPLRPEINRQIEKWAGQLLDLAEKIFQEGQITQAIAAARQIPSNTTAAGLVQERITRWQSIWNEAEKLYKNAESELEKENWNQALGYMRQLLSVENTYWETVRYDSLNELIRVTQQDGQTLAKARSLAEQGELKNITEAIALVDKIEPQSKLYKKSRSLATDFSKQILALARKNGDDQKWEDAIYIARQVPGNSSIKKEAEDFIELTRARSIATRVTVRSLEDAIAKAQVIGPDRPGHLEAKRLISQWQDSIKDVAYLEQARNLAMAGNVNNLRSAIAQAQLVSRTNLVWDRAQEEINDWQSQIEETEDRPYLRQAEQLASYRDRASLQAAIDTARNVGSGRALYTEAQDKIQGWNQEIQRLEDQPILDRAWNLAQWGNITGAIATAQGIRPGRLLYSEAQSAIQTWQQEGRDRQLLDRAYQLGDVAQSPERLIQAMDLANQVSSKSNLRFSADAAIQDWSQRILALAQQRSLENLPQAIELARMIPFYSNLYNQARQEVEAWETILNPPPVQVREPSPVAGDRSSTPTPFPQETPTESVNPPVSPTEPTATPTDLPATSAPPMPSDRNEGLGRDSQTPPPIERIE
>NC_019693|6607210:6661213|6651695_6652478_-|WP_015151325.1|DBSCAN-SWA
MNRYLSTLALFWKTAIAAELEYRVNFAIAAFSSLGNLAGSWFALSLFYGADYNFAGWQWEEALVVLGVFTILQGFSSTFLAPNLNTIVKQVQEGTLDFVLLKPISSQFWLSGRTISLWGLPDIILGLLLIFYAGSQLNLPPVNYLVSFIPLLFGSISLYSLWFMLGAMSIWFVKIYNVTQVLRGLLEAGRFPMVAYPTAYRFFFTFIVPVAFLTTVPAESVLGRVELSWIAGAALLAIALFLASMAFWRFALRFYTSASS
>NC_019693|6607210:6661213|6627129_6628092_+|WP_015151314.1|DBSCAN-SWA
MDTALQSQRNRSYAIIGTGAIGGFYGAKLQQAGFEVHFLLHSDYQFVRQRGLRVDSVWGDFTLDSLNVYNDVHQMPPCDVVIVALKTTRNSLLTTLLPPVLKESGAVLMLQNGLGNEEAIAPIVGPAHILGGLCFICSNKVGDGHIHHLDYGTITLGEYAPDYQPLGITATLQDIAGDFEAAGIPIQFAEDLLLARWKKLIWNIPYNGLSVVLNARTDEIMKNEYTRLLSEQLMQEVGAVAAAYNRKIPESFIQKMLDHTAKMKPYITSMKLDYDHHRTLEIESIIGNPLQAAIAKQIPVPKIAMLYAQLNFINSQIQAK
>NC_019693|6607210:6661213|6659535_6660765_-|WP_156823964.1|transposase|DBSCAN-SWA
MRQVSVQNEKWLRTFSPSSTALAPDYTDCVNTKLRSKKIQIYPSPELNKVWRKWLAACRYCYNQAIALQKSGKRLSKLKLRNEVMQSDLPAWVKETPCHIRQNAIFDAHLAFSASSDARFRSCRDSSQAIKFNDANFSSGSWYPRLTKGLTFRVSEPIPKTCDQGTQLVFTKGRWFAVFPEPVAFIPTEATGVIALDPGVRTFITGFDGSRFLEFGSGDIGRITRLCQHLDDLMGRIAKEPNRSKRRRMKQAAQRMRTKIRNLVDEAHKQIAHYLTRNYSVIFLPTFETSNMVAKAKRKIRSKTARAMLTWAHYRFKLTLKHQAEITGTTVVDVTEEYTSKTCTHCGHVHSKLGGSKVFRCPECGVTLPRDWNGAFGIFLKALRDTASVTLTGNSAIVALSGNNRKNVA
>NC_019693|6607210:6661213|6622985_6624704_-|WP_015151311.1|DBSCAN-SWA
MNDFPDFSANGYKIIRELGHNRAGGRVTYLALNQQRQESVAIKQFQFATSGSDWSAYRAVEREIEVLQQLNHPGIPQYLDSFETADGFCMVQEYKDAQSLAVPRSFEADEVKALAIAALNILVYLQTRTPLVIHRDIKPENILVSDRLTLYLVDFGFAKLGSEDVAMSSMVKGTMGFMPPEQLLNRQLSAASDLYGLGATLICLLTGTRSVAIAELVDDDYRIQFKHLMPKVSWRWIEWLETMVQPHPGERFPDAATALAALEPIYVVRTPEVHLSKTHITATASTLGEQITHTLSIKNPVPDTRLRGKWQVAPHPQDPPHRPDAHAWISFSPAHFKNNRLDAKIIIDTRQLRANQTYQRELLLENNGMPNPIRIPLEITTAPIPILTQKLPYSSLGLLFLAAGAGGMLALHSIATPIAIALSGFLGWAGLAKLTGKQGFVVKFLLTSVATTLIAAIAGFTLGMAAGASLIGSWATAGTLAATAVTGVALILAASGITKEFGLQIATALSLLTAASGISCGIALQLGFWTPLLIAAAAITGIPVIGVMVWLPIKRSRLKAQYRRSEEHLIAP
>NC_019693|6607210:6661213|6617742_6618579_+|WP_156824109.1|DBSCAN-SWA
MTAIGSAPAFAGTLTNPQFGGTAASDYLSYCSNGSSTYAGPTCTDSLSTILSGNSSAPGGNIELAASSEQGGFDFTKNTALTGKIGGKDIVISSLTQSDWMSVLGNGKTLLSQWLDDAFLAHSISSEFKPFVQQAFLANNGMQRFSDPNISYVNQDNATGEISIGLAGHFNASNMLKEALGNHPLLSLFVPNEVKASELVKVIYDNGPAKFLYSFTATDALQANKHGVGADGVSHNGNYEVKLAGVPVTSVPEPSTMLALMAVGGLVATSKRKSAKNA
>NC_019693|6607210:6661213|6618740_6620561_-|WP_015151307.1|DBSCAN-SWA
MVQTPQSPAIAQLENPQEWDLSDLYQGFDDPQIEQDLEVLQHRAAGFRRTYRGNVAALTPEQIADCLQELEEIGQISGYVYAYPSLTFSADTRNTEAKQLLDQVMESLTAIENQLLFFDLELQQISEENFNQLLASGELASYTHYLHRIAEFRPHTLSEEIEQTRNQDSLTGRQAFIQLRSVHLGEQEYEPVTTPDGKTASNEAELSALLFHPSPEVRYNTYLSVRNVLKQHNSLYGFILNTVTQDHRIESHMRQYSSTLHKQLLADEVSEPVFRAIMDGTASRFELFERYYQLKGKALGQKIRICDLYAPWTTEEEEPLPPVNYQTGVETLLNALQEFDVNYARRAEEFFLKNWIDAKVRPGKRGGAFCAYSHGKHSYLLLSYTDDYNSLFTLAHEMGHGLHFAWIDDAQSYYNSNPPLVLAEIASTFNELLLLDYLLKTAADNKALMKSLLTRQLEDQFNLLFRQSTISRLELAIHDRAKEGSFDAKFINDKWMELYRNLCGNAVELLPEHQYDWARIGHIFFKPFYCYQYAASNIVSLACYQKYLETGKDFIPGYLELLAAGGSMNQVEALRKYVDVDIENPQTIASALDYIEGLLDKLQASL
>NC_019693|6607210:6661213|6652676_6653876_+|WP_015151326.1|DBSCAN-SWA
MNEFTKILRDKKATIVEQWIALVREDENISTADKLPYAAIRDTLPNIIDAIASLLDPPEEGEEADLLQSALEHGYIRAQQGYEPQEIAREYGLAREMMLSAIEEELERAKPQVIIGVIRLIDKAMDKVIGRCFHSYTEERLQELENLQSQLHFTNQELSRLVRTSKENLAHLAHELKTPLNSIIGYSDLFLRQQRKHFSEINDSTPNMEHIERVLRSGRQLLQLINDTLEISRYDSGKMPLNLIEIPPKNLICQTAEMLETMAREKQINLEVNCDQAPELIVTDPLRLQQVVTNLLSNAVRYTPEGTVRIECRISSKQEWQIVISDTGVGIDEKDQAEIFNPYYRVMSEHQTVLPNSTGLGLAIVSRLVKLLQGKIEVVSQLNVGSTFTVTFPLQIQSS
>NC_019693|6607210:6661213|6631423_6631795_+|WP_156823968.1|DBSCAN-SWA
MRMGIEAMFKDCKTGGYNLEGTGANQERLTRLVLLIALAYTASSIQGVPIKQQGVQSCVARLTESGRSQRRHSNFWIGLYGLSWIDSLEKLQELSIEFMKLHPHKRPFYRRGLRAMSLIQSSF
>NC_019693|6607210:6661213|6628161_6628935_+|WP_015151315.1|DBSCAN-SWA
MDERLIKPGLPQPPTFDRLRDERLYRKQRLAAAFRLFAHFGFDEGVAGHITVRDPEFPDQFWVNPFGMYFGHIRVSDLVLVNHQGDILEGDRPINAAGFAIHSQIHQARPDVIAAVHAHSLYGKTWSTLGRLLDPLTQDACAFYGDHALFDDYTGVVLDVSEGERLARTLGNAKAIVLRNHGLLTVGHSVDEASWWFITMDRSCQSQLMAEAAGKPISIAPEIAQLTYAQVGSHYMGWFSFQSLYDMIVRQQPDLLE
>NC_019693|6607210:6661213|6645875_6646136_+|WP_044195992.1|DBSCAN-SWA
MDDGFILPLSENYTLIETDVEEVKEHLNIDYKFAHDRIQQAAYSLIPETEKSSVHWQIGQLLLQNTPVNEQEVKIFALGRRFSTRA
>NC_019693|6607210:6661213|6615585_6615909_+|WP_015151304.1|DBSCAN-SWA
MSSIIKVTDTEFGTEVEQATTPVLAYFWASWCGPCRLVSPYIDWAASEYGDRLKVLKLEVDPNPESVKKCGVEGVPAIRVFKDGAIVESFEGAITKQALATLIDAHL
>NC_019693|6607210:6661213|6639565_6639934_-|WP_015151319.1|DBSCAN-SWA
MTITLQKKPAVNSPVECPQELRNAWARVFAHAWSQEDREFLRRLNKDPRQTIEQIASGESSDSEQLCQACQTILEYVNDPNSEEGFLALPPLPEHLQRGNLSEEQLYTYANQDGLYGVLRVC
>NC_019693|6607210:6661213|6630958_6631339_+|WP_156823967.1|DBSCAN-SWA
MGSVIYQKRAWPVYWTFIDHTGASNLARQKAILTPIIRLLNGYKIIVVGDREFHSVELAHWLQSKKVYFALRQKCNTYIKQSRKKGEDFESLSNLGLQPGMKLYLPSVQFTKKKGFGRYALAVYWK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015151301.1|6607210_6610069_-|protease	zinc-dependent metalloprotease	NA	NA	NA	NA
WP_015151302.1|6611145_6613455_-	hypothetical protein	NA	NA	NA	NA
WP_015151303.1|6614098_6614995_-	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_015151304.1|6615585_6615909_+	thioredoxin	NA	NA	NA	NA
WP_015151305.1|6616073_6617246_+	LL-diaminopimelate aminotransferase	NA	NA	NA	NA
WP_156824109.1|6617742_6618579_+	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
WP_015151307.1|6618740_6620561_-	oligoendopeptidase F	NA	NA	NA	NA
WP_015151308.1|6620776_6621607_+	DUF4351 domain-containing protein	NA	NA	NA	NA
WP_015151309.1|6621678_6622509_+	DUF4351 domain-containing protein	NA	NA	NA	NA
WP_015151310.1|6622609_6622891_+	DUF4351 domain-containing protein	NA	NA	NA	NA
WP_015151311.1|6622985_6624704_-	serine/threonine protein kinase	A0A0M4JBJ9	Mollivirus	6.6e-10	30.6
WP_015151312.1|6624799_6625399_-	pseudouridine synthase	NA	NA	NA	NA
WP_044197962.1|6625510_6626416_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_015151314.1|6627129_6628092_+	putative 2-dehydropantoate 2-reductase	NA	NA	NA	NA
WP_015151315.1|6628161_6628935_+	class II aldolase/adducin family protein	NA	NA	NA	NA
WP_156823967.1|6630958_6631339_+	hypothetical protein	NA	NA	NA	NA
WP_156823968.1|6631423_6631795_+	hypothetical protein	NA	NA	NA	NA
WP_015151316.1|6632243_6634292_-	S9 family peptidase	F2Y2Z7	Organic_Lake_phycodnavirus	1.5e-48	29.4
WP_015147826.1|6634411_6635482_-|transposase	IS630 family transposase	NA	NA	NA	NA
WP_015151317.1|6635678_6636782_-	amidohydrolase	NA	NA	NA	NA
WP_015151318.1|6636794_6639050_-	TOMM precursor leader peptide-binding protein	NA	NA	NA	NA
WP_015151319.1|6639565_6639934_-	hypothetical protein	NA	NA	NA	NA
WP_015151320.1|6640067_6640391_-	hypothetical protein	NA	NA	NA	NA
WP_015151321.1|6640738_6642211_+	Dyp-type peroxidase	NA	NA	NA	NA
WP_015151322.1|6642463_6643570_+|transposase	IS630 family transposase	NA	NA	NA	NA
WP_052315802.1|6643572_6644085_-	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_044197969.1|6645374_6645791_-|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_044195992.1|6645875_6646136_+	hypothetical protein	NA	NA	NA	NA
WP_083896824.1|6647884_6650980_+	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_015151324.1|6651096_6651390_+	membrane protein insertion efficiency factor YidD	NA	NA	NA	NA
WP_015151325.1|6651695_6652478_-	ABC transporter permease	NA	NA	NA	NA
WP_015151326.1|6652676_6653876_+	sensor histidine kinase	A0A1V0SGX0	Hokovirus	2.8e-23	31.7
WP_015151327.1|6653971_6654760_-	ABC transporter permease	NA	NA	NA	NA
WP_015151328.1|6654890_6655889_-	ATP-binding cassette domain-containing protein	A0A2R8FG22	Brazilian_cedratvirus	1.2e-19	31.9
WP_044197974.1|6656009_6656843_-	hypothetical protein	NA	NA	NA	NA
WP_015151330.1|6657146_6658301_-	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_156823964.1|6659535_6660765_-|transposase	transposase	A0A1V0SAM8	Catovirus	2.0e-24	27.6
WP_015150029.1|6660619_6661213_-|transposase	IS607 family transposase	Q331V0	Clostridium_botulinum_C_phage	3.9e-42	43.7

Sequences of DBSCAN-SWA_5

Nucleotide sequences of DBSCAN-SWA_5

>NC_019693|6942853:6953551|DBSCAN-SWA
AATGGGGCAAAAGGGGGTGGCTATGACGAATCAGAATCCGGGATCGATGGATGTTGAGGCAGGCGATCGCCTCACTCAATCCCTTCAAGAACAGCTTGCATGGACACAGCGTCGTTGTGAAGCATTGGAGTTGGCGTTAGCACAGAGGCAAGCGGAATTAACAAAGGCTCGGACTCAGCAAGAAACCGCAGCAAGCTCTCAAAAAAGTGCTGAACTATACAAAAGAATTTTTGAAAAAGCACCGATTGGGATGGTTTTAATGAGTTGGAAGACGCTAGGTTTTGTGCAAGTTAATCCCACCTTTTGTAATCTATTGGGCTATTCTGATTCAGAACTGGCGACTCTGACTTTGGAGGAGATTACCGCTTCAGAAGATTGGGAAACGGACTGGGAATTTCTCCGGCAAAGGATTGAATGCCAGGAAATGTCCAACTATCAAACAGAGAAACGGTTGATTCGCAAGAATGGGGAGGTTTTGTGGGTGCATCTATGCATCTCGGTCCTGGAGGATTGTCAGGGGAATCCACTGTATCTGTTGGTGACAATTCAGGATGATAGCGATCGCCTCGGCACTCAATGCGCCCTCAAGGAGAGTCAAGAACGACTACAAAACGTCTTGGATACCTTGCCGCTTGGGGTTTGGATTACCGATGCCGATGGGACGATCCTGCAAGGAAATCCGGCGGGGCAAAAAATTTGGGGCGGTGCTCGATATGTGGGAATAGACAGCTATCATGAATATAAAGGATGGTGGCCCGATACAGGAGAGCAACTCTCTAGCGAAGAATGGGCGTTATCCCGAACGTTGCGAACGGGACAAAGTATTTTAAATGAAGAAATTGATATTGAAGATTTTAACGGCAAGCGGAAAACAATTCTCAACTCGACGATGCCGTTACGAAATCAATCTGGGGTGATGGTTGGGGCAATTTTTGTTAACCAAGATATCACAGAGCAACGGTTGGTAGAAAAGGCATTGTGGGAAAATCAGCGGTTGATTCAACAAATTGCTGATGCGACTCCCACAATTTTATATCTGTATGACTTGCTGGAAAATCGGAATATTTATTTCAACAAACATCTCAACGAGATTCTCGGTTACCTTCCCGAAGAAGTGCAAAAGATGGGGCCGGATTTTTTGCAGAATTCGATTCATCCAGAGGATTGGCCGAGGGTGGTGGAAAACCGCGTCAAATTAATGTCGGCTGCCGATGGAGAGATTGTTGAAACCGAATATCGGATGCGTGATGCTCAAGGAGAATGGCACTGGTTGGTGAGTCGAGATACTATTTTTTCGCGCACGCCGGAAGGGTCTACAAAACAAATTTTAGGGATGGGTTTGGATATTAGTCTTCGCAAGCGAGCAGAGGCAGAATTGCTGGAATATCGTCAACAATTGGAGGCGTTAGTTGAGCGGCGCACGGCACAGCTTCAAAACACTAATCAACAGTTGGAACGAGAAATTGCCGATCGCATTCGCGCCGAGGTCCAGCTTCGGGAGAGCGAAACTCGCTATCGATTGTTGGCTGAAAATGCCACAGATATGATTTCAACTCATACCCCCGAAGGAGTATATCAATATGTTTCCCCTTCCTGCTTCACCCTGCTGGGGTATCACTCCTCGGAATTAATCGGGCATTCGGCTTATGAATGGATACATCCTGATGATATCCCCGGGGTGGAAATTTCCCATCGGGCGGTTTTAGAAGTGTTGGGACCGTTCCAGTTTGTTTACCGGGTTCGTCATCAAGACGGACATTATATTTGGTTTGAGACGAACGCTCAGGCTGTCTGTCATCAGGAGACAGGTGAGGTGGTCAAAATTCAGGCGGCTTCCCGGGATATCAGCGATCGCCAGCGCATCGAAAAAGAACTCGCCCAACATACCGCTGATTTAGCCCGTTCTAATGCGGACTTAGAGCAATTTGCATACATTGCCTCTCACGATTTACAAGAACCCCTCCGCATGGTTGCTAGTTATACTCAATTATTAGCCCTGCGTTACCCGGGAAAACTCGATGCTCAAGCGGATAAATACATTGCTTATGCCGTGGATGGCGCAACTCGAATGCAGCAACTCATTCATGACCTTTTACAATATTCCCGGGTTGGAACCCACGGCAAATCCTTCGATTTTGTGAATTGTAATGACATTATGACCCAGGCTATTTCTAATTTAAAACTTGCTATTCGTAAAAGTGAGACTGGAATCACTTGGCAGAATTTGCCCCAGGTTTTCGGGGATCACACTCAATTACTTCAGTTGTTTCAAAATTTGATTGCTAACGCGATTAAATATCGAGGTTTGCAACCGCCCAAAGTGCAAATTGATGCCCGTGAACTGGAGGGAGAATGGTTGTTTTCTGTGCGAGATAATGGCATTGGTCTCGACCCCAAACATGGCGATCGCATCTTTCAAATTTTCCAACGGTTGCATACCCGGGAGGAATATCCCGGGACCGGAATTGGATTAGCTATTTGTAAGCGCATTGTCGAGCGCCATCGCGGTCATATTTGGGTTGAATCTGAACCCGATCATGGGGCAATTTTTTACTTTACTCTGGCTAATTCTAGTCCCCTTGAGGCGTGATTTCTGCTCCGTCACCCTTAACCCACCCTGACTCTTGTTCCAGGATGGCAGCCTCAACCCAAGGGAAAGTCGAATCCGGGGGGCGATCGCTAATCGGATACCGATTAAAAAAGAGCAGCGTCATGGATTTGGGTTGAAACCCCGAGCCTGACGCGATGTCAAGGACTGAAACTGCCGTTGCTACAAACAGAATCATTCTACTTTTTGGGGTTGTGGCTACAGATTTTTCTAAAAACACTTGAAATTTGACTTTTTAAATGATAAGATTTTTAGCCAACCTGCTTTTAATAACACAGGATTCGGCTCAAACTGATATCAATCCCGATCGCGCTTGACTCCTTCCTGGCTCTGAAATCCGCACTGCCAAACTGCCAACTTAGCCTCTCCCACTCAGGATTCCGAATGGATGGAAAGGCCCTATCTTGCGGATAATTTTCCTCTAGACCCAATCTCCGGTAAGCCCCGCTCAGAGTTTACTCAATCTCATGGAGAACCACTATGAATCCAGAATTGATAAATATCCTATTAGTCGAGGATAATATCGCGGATGCCGAACTGTTCCAGGACATTTTAGACATAAGTCCGGAGAGTCAGGCTTGGAACGTAACTCATGTGATGCGATTAGCAGAGGCCCTTGTTCAACTCGATCGCGATCCCATCCAAGTCATTCTGTTAGACCTCTCACTTCCGGATAGTCAAGGGCTCCAAACCCTCGTGACCCTGCGGGAAAAAGCCCCGACTCTCCCCATTGTGGTCCTAACCGGGTTGAATGATCAACAGATGGGGATTACAGCAGTCCGCGAAGGTGCTCAAGATTACCTGGTGAAAGGGTTAGTCAGTGGAGGGATGATCACCCGCTCAATGTTATACGCGATCGAGCGCAAAAAAAATGAAATTGCGATGCAGTCCTGCTTAGAACAAGAACGGGAACTCCGAGAAATCAAATCTCGATTTATCTCAATGCTCTCTCATGAATTACGCAATCCCCTCACTACTATTCTGGCATCGGCAGACTTGATGGAAAAATGGGCGGAGGAATTGAGTGAGCAGAAAAAACGGGAGATGAATCGGAAAATCAAGGAGTCTGCCACACGCATGAATAAAATCCTTGATGATCTGATGGTACTCTGGCATCATGAATCCCTTGCACCCACGCCATTGAACCCCAGTTGGTTTGATTTGCCGGAATTTTGCCAAAAGTTGGTGGCTGAGTTTCAAATCCAACTGGATAATCAAGGCTCCCAACGGGCTAATTCTCTTGAGTTAATATGGGTGAGTCAGATCCAGTCCTATCCGGTGTACTTAGACCTCAATCTGCTGGAACAAATTTTGTCCAATCTGCTCTCAAATGCAATTAAGTATTCTCCCCGTGGTGGCCCGGTGAAATTTGAGCTAACTGTGGACTCCAATCAGGTAATTTTTCGGATTCAGGATTCCGGAATCGGGATTCCTCCATCCGAGCGCGATCGCTTATTCACCTCGTTTTATCGCGCCAGCAATACCCAGGGAATCTCCGGAACCGGCCTGGGTTTATCCATTGTCAAAAAGGCGGTAGATTTGCAAGGGGGGACGATTCACGTTACCAGTGATGTAGCAATGGGGTCTACATTTACGGTGACCTTACCCTTAAGGGTTAGCCCCGTTTTAATGGACCCCTCGAACTGTTCAAACCCTGTTTAATTCAACTCAGCCTGGGCGGGCCTCGGGGTGAGGCATCGCTGCCCATTTTAAGAGGTTGAATGAAGCAAATATGAGAATAATTTCCTGCAAATGTCATCAAGAATTAAGGTAAAATCAGGAAAGAATTTAGTTCCCCTTATAATCATTTTTGTTGGATGAAGCATAAAATATGAAAATTTTATTAGTGGAGGACAATCTGGCCGATGCGGAACTTATACAGGAAATATTATCAGAGTTTAGTGAGGAAGAGTTTACGTTTGCTCACGTTTGGCGGGTCAGGGAAGCCGTAAAACTGTTGGCGGAAACTGAGTTTGATGTGGTTTTATTAGATTTATCTTTGCCGGATTCCTGGGGATTAGAAACGCTGATGGAAGTGCAAACCCAAGCCCCCACGATCCCGGTGGTGGTGTTGACGGGTTCTCAGGACGAAGAACAGGCAGTCGAGGCGGTTCGCAAAGGTGCACAGGATTATCTCCTCAAGGGACAACTGGTGGGCGCACTGTTAGTCCGGGCGATCCATTATGCGATCGAGCGTAATCGCACCTTAGAAGCGTTGCGGCGCAGTGAGGAGCGATTTCAAACCTTGGCAGCAGAACTGGATTTGCAAGTCCAAGAACGCACCAGGCAGTTACAACGCGCTTTAGAAAAAGAAGCGATGCTGAATCGGATTACCGAGAAACTACGGGATAGTTTGGACGAACGGCAAATTTTGCAGACGGCAGTCCGAGAGTTGGCGGTTGCTTTAGAGTCGGATTATTGTAATGCTACTCTCTACCTCACGTCACCCCAGACCAAAAGGATGTGCTATGAATATGCTCACGACAGACTGTCGGATTTAGGGGAGGCGATTAGGCAGGTTCCGGAGATTTATGGACCGTTGGATCAAGATTGTATGCAGTTTTGTCCCGTCTTCCTCCATGAGTTTCCCGAGGGAATGACCATTCTGGTGACTCCTATTTTCGGCGAAAGTGGGGCGATCGGGAACTTATGTTTATGCAAACCTGCTCAGGAACAATTCAGTTTCACAGAAATCGGCCTGGTTGAGCAAGTGGCTTCCCAATGCGCGATCGCCGTCCGTCAAGCGCGATTGTATCAAGCATCCCTCGCCCAAGTCCAAGAATTAGAGCGGCTGAATCGCTTGAAAGATGATTTTCTCAGTACCGTTAGCCATGAATTACGCACCCCGATCGCCAATATCAAAATGGCGGTGCAAATTTTGGAAATGGTGGAACAAAAACGGCAACAGGAGTCCTCTGCGGTGACAACCCCATCGGAGGGGAGAGAGAGTAAACCGCCTCATAGCCTGGATCATGCTGAGGGGTATATTAAGATTTTGCGGGAAGAGTGCGATCGGGAAATTCGCCTGATTGATAGTATTCTGGAGTTACAACGCCTGGAAGCGGGGATCGAACCCGTCTCTTTCACCCCGGTTTTGATCCAACAGTGGGTGGGAAATGTGATCGCGCCTTTTATCCAAAAAGTGAAAAGCACTCAACAAATCTTGGATCTGGATATCGACCCCGCACTTCCCCCGATTTTGTGTGATTCAGATATCTTGCAAAGAATTCTCACCGAATTGCTAGAAAATGCCTGCAAATATACCCCCGCACAAGGCCGGATTACTATTACGGCGCGGTGCGATCGCTCCCGGTTACATCTGAAAGTTAGCAATTTCGGCCTAGAAATCCCGGCCACGGAATTAACTCACGTCTTTGATAAATTTTACCGCGTTCCCAGTTCCGACCCTTGGAAACATGGGGGGACGGGATTGGGATTAGCCCTGGTTCGTAAACAAACCGAATATATCGGGGGTCAAATTAAAGTGACCAGCGCATTGGGGGAAACCTGCTTTACTGTAGAATTGCCCCTCTCCCCCATATAGTCACTCACCGAACTTTGTGAGCGGGTAAACACCGGGTCCGGAATCCCCCCGGGCATCATCCCAGGTTTATCCCTTCACTCTCCTGTGAATTTCTCCAGTTCGGGTCTGGATTTGACTGCTCAAACCCAAACCTGACCCTGTAGAATGGGAATAGGTTATCACGAATTGTTAAGGGCCTCCCTTGGATTATAATGCTGAATCATCCTGACTCCCCCCAAGTTTACGATGCTGTCCTGGGCGGGCAAACTCAGCCCCGAGCCTTGATTGCCCAATTGGATTTAATGATTCGGGCGCGTTATCCCATTCTTTACCTAGTGGGTGTAGAAGAAGAACCTGTGGAGGAAGTATTGCACAAAGTGGCTCAATTGTCAATGCCCCCTCGGAAACTTTTGTTCTGGGATATCGTGCGAGGGTGGGGAGATAATGGATCAGCAAAAGGATCAGCAATGGCCGCCCTCGATCGCATCGCCAAAGCACCCCCGGAAGATTCCCTCTTTGTCTTACGCGACTTGCACCCAGTCCTCAAAAACTCCACCTCGGACAAAACGATGCCGGTGATTCGGGAGTTGCGAAATCTCACCCGGGAGTTGCAGCGATCGCGAAAAACCCTCATTTTAACCGCCTATACCCTCGCCATTCCCCCAGAATTAAGTGAGGAAATCACCGTCATCGATTTTCCCCTTCCCGATGCCGCCCATATTAATGCCTTAATTACAAAATCCGTTAGCCCAGAACAACTTAAAATCACAGGATTAGCCCGAGAACAATTAATCAAAGCCTGCCAGGGATTAAGTCGCACCCGCATTCAGCGCGTTCTGGCTAGAGCATTAGCAGACAAACAACAAGTCAACGAAACCGACATTGAAAGCGTCCTGGATGAGAAAAAACAAGCCATTCGCCAAACGGGAATTTTAGAGTTTTTACCCGCCCGAGAATCGCTGAAAAATGTGGGAGGATTAGATAACCTCAAAACCTGGGTGAGAATGCGAAATGACGTCTTTAGCGAAGAAGCCCGCCGCTATGGAATTCCTAACCCGAAAGGCGTGTTACTCGTCGGCATTCAAGGGACAGGAAAATCCCTCTCTGCCAAAACCATTGCTCATGAGTGGCGCTTACCCTTATTGCGCTTAGATACTGGGAGATTATTTGGGGGAATTGTCGGAGAAAGCGAGAGTCGGTTGCGCCAAATGATTCAACTGGCGGAAGCGATGTCTCCTTGTGTGTTATGGATTGATGAAATTGATAAAGCCTTTGGCAATATTTCCGGAGGAACCGATGGGGATTCCGGGACCAGTCGTCGGGTATTTGGGACATTAATTACCTGGATGCAGGAAAAAACTGCTCCAGTTTTTATTGTGGCAACGGCTAATAATGTCCGGATTTTACCCGCAGAATTGTTAAGAAAAGGACGATTTGATGAGATATTCTTTTTGAATTTGCCTACAGAAACCGAACGTCGGGAAATTTTTAAAGTTCACCTGATGCGACTGCGCCCCAGTCGGTTGCGGGAGTTTGATTTAGGATTACTCGCCCGTCAAACGAACAACTTTAGTGGGGCGGAAATTGAACAAGTGATCATTGATGGAATGCACCGAGCATTTGGAGGAAAAACGACGGAAAAACGCCGAGATTTTACCACGGAGGATATTTTGCGTGCCAGTGAAGAAACGGTCCCCTTAGCAGCGATCGCCCGCTATCAAATCGAAGAACTAAAACATTGGGCAGCAGAAGCCGGTGCCCGAACCGCTTCCAATGATACCGAATTAACCGAGGAATTAAAACAGTGGTCCATCCAAAAAGGCATGGATTCACTGGACTCCGATTAGACCTTGTAAATAGTCCCAATTACTTAATTGATTTAGGAATAACTATCATGTCTCATTTTACCACAATTCAAGTCCAAATTAAAAACGGCCAAACCCTCTATCGTTGCTTGCGAGAGTTGGGGTATCACGTTGAGGAAAATACCACAGTCCGAGGGTATAAAAATCAAACTACTCAGGCGGATTATGTGGTTCGACAAAAAAATGGATATGATTTAGGATTTCGTCGGACTGGAGAGACTTATGAGTTAGTGGCAGATTTTTGGGGGGCGCGAATTAATCCGGAGCAATTTGTTGAGAAAGTGACTCAAAAATATGCTTATAAAACCTTGATGGTATCTGTAGAAAAACAGGGATTTCAGGTAGAAAAAGAGGAACAATTAGAGGATGGCACCTTGCGGGTTGTGGTGGGTAAATGGATGTAGAGTAACAACCCAACCGACTGTAGGTTAAAACCCTGTAGGGGCGCTTCTCGAAGCGCCCCTACCGTCGGGGGTTAAAACGTTGGCGGACTAATAGCTAAAGTCGGTTAAAACCGACTAAAAACATCACGGAATAACCCTGTAGGGGCGCTTCGAGAAGCGCCCGACCAACAGAGTTTTTCACCCCGACCCGGTATTGCTACCCGCCGGTTGTTGATAAAAATGACCCACCCAAGCGCGAAACAGGAGTTAAAAAATGTCCCATTTCACAAGTATTCAGACGGAAATTCGTCAGATAGAGTATTTGACAAAAGCATTAGCGGATATGGGGTTTGAGTCGGTGGAATTGCATGAATTTCCGGTGCCACTGTATGGATTTGAGGGAGATATCCGCCCGGAGTCGGCTGAGGTGATTGTGCGGCGGAAGTTTATCAGTTCTCGGAGTAATGACCTGGGATTTAAACGACAATTTGATGGAACATTTATGGCAGTGATTTCGGATTATGATTCTCGTCAATTTTCTCGGGACTGGATTCAAAAGTTAACTCAGCGGTATGCCTATCATGCGCTGATAGGAACTGCGCCTCAACAAGGGTTTACAGTTGAGGAGGAAGAGGTTTTAGAAGATGGGACAATTCGGGTGATTATTGGGCAGTGGGTATAGGGGATGGGGAACGACTTCAGTCATTATTAGGAACCTCGGAAAGATAACGACTGAAGTGGTTTATTTTAGTTTAGCGATCGCCTCTTGATCGACTAAGGTTTCTCCGGTGACTAAATCGCGGACGGTTGCCAGTAAAACGCGCCCTGAGTTGACTTCAAATCGGACAGAAATGCGATCAATACCGATTTGTCCCGGAGGATTGAGATGGGCGACACAGACCCGATCGCGATCGAGATCTAGGGACCGATATTCTTCCCGTTTGTGCAATGCACCTCCGATCATCCGTCCCGATTCATCAAACATCACTTCGGCGTGAGAAATTTCGGCGACTTCCCCGATATCTAGGCGGATTTCTTGTTGTCCCTCGATCGCCGCTTGCAACATCAACGGTTCCGATCGCTGGCAGGGATAGGTTACCCCTTTTTCAAACAAAGGAAAATAGGAGTAGGTTTTACAATGGGGGTCCCATAGACGAATGGCGTAACTGTGGCGCAAATAATCTGCGATGATCACTGCGTCATTTAAAGCTAACGCACCATGCGCCACTGCTTCAAAGGGTTTATCCATTTTCACCCGCGATCGGCCAAAATAGGAGACAATCAAAGTCTGAACTGCTGGAATTAAACAACTCCCCCCCACTAACAACACCTGTTCAATTTCTGCCTTACTAATTCCTTTCCCTTGGGCGACTGCCAACACCTCATCCAAGGCCCCGCGCAACTGTTCTAAGAGTTGATGATAATCTAACAGCGTATCAAAGCGATCGCGACTTAATTCGACTTCGTAGGACATAAAATTTTCATCATCAAACCATACCTCTTTCGCCTCCGTTGCCCGAGACAAGCGCATTTTTAATTTTTCAGCAATTTCTAATAACCGTTGCCAGCCAATTTCGCCAATTTGGGACCGGGATAACCCCTGGCGTTGCAGATAATCTTCCACAATCCAAGTATCAATATCCACCCCGCCAATATAAGCATCAGATTTCGCTAAAACCTCCGCTTGTAACGCCGAGTTTCCCGGTTGGGCCCGATTCGTGCGAATTAAGCTCAAATCCAGAGTTCCTCCGCCAAAATCCACCACTAATACCACAGAACCGGGTTTTTTAATGGCATAACCCAGGGCCGCTGCGGTGGATTCATCAATAATATTAATCTCAGCAATGTCCAGGCGACTGCCCAATTCTCGAAACCAATCTAAATAGCGCTCAAATGCCCCTACAGGAACGGTAAAAATCAGTTTACTGGGTTTGATTCCGTCCCGAGACAGACGATGGCAAATTTCTTTTAAAAAAGATTCACAAATGGTAGATGCGGAGTAACTCAATCCATCTAATATCCGGGGTGGAGATTGAAAATCCGCCGCCAAATCTCGTTTAAATCCTTGAAAGAATCGTTCCGGTTCAGCCTGTCCTAGCCGGGTGGCCATCACTTGCTGTCCTACAACAATTTGATTCCCTTTTTTAATAAAAACAACCGTTGGAATAACGGGAATTTCTAAATTTTCCCCAGTCTGTTTTTTAGCTTTAAAAATTCGGGAAATTTCCCCAAATCTTAGGGTTTCTGGGGCATGATTATCGGGGTTAAGAATACTAATAACGGTGTTACTGGTGCCAAAATCAATCGCGACTACGGTCAT

Protein sequences of DBSCAN-SWA_5

>NC_019693|6942853:6953551|6951505_6951913_+|WP_015151552.1|DBSCAN-SWA
MSHFTSIQTEIRQIEYLTKALADMGFESVELHEFPVPLYGFEGDIRPESAEVIVRRKFISSRSNDLGFKRQFDGTFMAVISDYDSRQFSRDWIQKLTQRYAYHALIGTAPQQGFTVEEEEVLEDGTIRVIIGQWV
>NC_019693|6942853:6953551|6945422_6945638_-|WP_044196048.1|DBSCAN-SWA
MILFVATAVSVLDIASGSGFQPKSMTLLFFNRYPISDRPPDSTFPWVEAAILEQESGWVKGDGAEITPQGD
>NC_019693|6942853:6953551|6947291_6949004_+|WP_015151549.1|DBSCAN-SWA
MKILLVEDNLADAELIQEILSEFSEEEFTFAHVWRVREAVKLLAETEFDVVLLDLSLPDSWGLETLMEVQTQAPTIPVVVLTGSQDEEQAVEAVRKGAQDYLLKGQLVGALLVRAIHYAIERNRTLEALRRSEERFQTLAAELDLQVQERTRQLQRALEKEAMLNRITEKLRDSLDERQILQTAVRELAVALESDYCNATLYLTSPQTKRMCYEYAHDRLSDLGEAIRQVPEIYGPLDQDCMQFCPVFLHEFPEGMTILVTPIFGESGAIGNLCLCKPAQEQFSFTEIGLVEQVASQCAIAVRQARLYQASLAQVQELERLNRLKDDFLSTVSHELRTPIANIKMAVQILEMVEQKRQQESSAVTTPSEGRESKPPHSLDHAEGYIKILREECDREIRLIDSILELQRLEAGIEPVSFTPVLIQQWVGNVIAPFIQKVKSTQQILDLDIDPALPPILCDSDILQRILTELLENACKYTPAQGRITITARCDRSRLHLKVSNFGLEIPATELTHVFDKFYRVPSSDPWKHGGTGLGLALVRKQTEYIGGQIKVTSALGETCFTVELPLSPI
>NC_019693|6942853:6953551|6945940_6947122_+|WP_015151548.1|DBSCAN-SWA
MNPELINILLVEDNIADAELFQDILDISPESQAWNVTHVMRLAEALVQLDRDPIQVILLDLSLPDSQGLQTLVTLREKAPTLPIVVLTGLNDQQMGITAVREGAQDYLVKGLVSGGMITRSMLYAIERKKNEIAMQSCLEQERELREIKSRFISMLSHELRNPLTTILASADLMEKWAEELSEQKKREMNRKIKESATRMNKILDDLMVLWHHESLAPTPLNPSWFDLPEFCQKLVAEFQIQLDNQGSQRANSLELIWVSQIQSYPVYLDLNLLEQILSNLLSNAIKYSPRGGPVKFELTVDSNQVIFRIQDSGIGIPPSERDRLFTSFYRASNTQGISGTGLGLSIVKKAVDLQGGTIHVTSDVAMGSTFTVTLPLRVSPVLMDPSNCSNPV
>NC_019693|6942853:6953551|6951973_6953551_-|WP_015151553.1|DBSCAN-SWA
MTVVAIDFGTSNTVISILNPDNHAPETLRFGEISRIFKAKKQTGENLEIPVIPTVVFIKKGNQIVVGQQVMATRLGQAEPERFFQGFKRDLAADFQSPPRILDGLSYSASTICESFLKEICHRLSRDGIKPSKLIFTVPVGAFERYLDWFRELGSRLDIAEINIIDESTAAALGYAIKKPGSVVLVVDFGGGTLDLSLIRTNRAQPGNSALQAEVLAKSDAYIGGVDIDTWIVEDYLQRQGLSRSQIGEIGWQRLLEIAEKLKMRLSRATEAKEVWFDDENFMSYEVELSRDRFDTLLDYHQLLEQLRGALDEVLAVAQGKGISKAEIEQVLLVGGSCLIPAVQTLIVSYFGRSRVKMDKPFEAVAHGALALNDAVIIADYLRHSYAIRLWDPHCKTYSYFPLFEKGVTYPCQRSEPLMLQAAIEGQQEIRLDIGEVAEISHAEVMFDESGRMIGGALHKREEYRSLDLDRDRVCVAHLNPPGQIGIDRISVRFEVNSGRVLLATVRDLVTGETLVDQEAIAKLK
>NC_019693|6942853:6953551|6950877_6951252_+|WP_015151551.1|DBSCAN-SWA
MSHFTTIQVQIKNGQTLYRCLRELGYHVEENTTVRGYKNQTTQADYVVRQKNGYDLGFRRTGETYELVADFWGARINPEQFVEKVTQKYAYKTLMVSVEKQGFQVEKEEQLEDGTLRVVVGKWM
>NC_019693|6942853:6953551|6942853_6945442_+|WP_052315810.1|DBSCAN-SWA
MGQKGVAMTNQNPGSMDVEAGDRLTQSLQEQLAWTQRRCEALELALAQRQAELTKARTQQETAASSQKSAELYKRIFEKAPIGMVLMSWKTLGFVQVNPTFCNLLGYSDSELATLTLEEITASEDWETDWEFLRQRIECQEMSNYQTEKRLIRKNGEVLWVHLCISVLEDCQGNPLYLLVTIQDDSDRLGTQCALKESQERLQNVLDTLPLGVWITDADGTILQGNPAGQKIWGGARYVGIDSYHEYKGWWPDTGEQLSSEEWALSRTLRTGQSILNEEIDIEDFNGKRKTILNSTMPLRNQSGVMVGAIFVNQDITEQRLVEKALWENQRLIQQIADATPTILYLYDLLENRNIYFNKHLNEILGYLPEEVQKMGPDFLQNSIHPEDWPRVVENRVKLMSAADGEIVETEYRMRDAQGEWHWLVSRDTIFSRTPEGSTKQILGMGLDISLRKRAEAELLEYRQQLEALVERRTAQLQNTNQQLEREIADRIRAEVQLRESETRYRLLAENATDMISTHTPEGVYQYVSPSCFTLLGYHSSELIGHSAYEWIHPDDIPGVEISHRAVLEVLGPFQFVYRVRHQDGHYIWFETNAQAVCHQETGEVVKIQAASRDISDRQRIEKELAQHTADLARSNADLEQFAYIASHDLQEPLRMVASYTQLLALRYPGKLDAQADKYIAYAVDGATRMQQLIHDLLQYSRVGTHGKSFDFVNCNDIMTQAISNLKLAIRKSETGITWQNLPQVFGDHTQLLQLFQNLIANAIKYRGLQPPKVQIDARELEGEWLFSVRDNGIGLDPKHGDRIFQIFQRLHTREEYPGTGIGLAICKRIVERHRGHIWVESEPDHGAIFYFTLANSSPLEA
>NC_019693|6942853:6953551|6949195_6950830_+|WP_015151550.1|DBSCAN-SWA
MLNHPDSPQVYDAVLGGQTQPRALIAQLDLMIRARYPILYLVGVEEEPVEEVLHKVAQLSMPPRKLLFWDIVRGWGDNGSAKGSAMAALDRIAKAPPEDSLFVLRDLHPVLKNSTSDKTMPVIRELRNLTRELQRSRKTLILTAYTLAIPPELSEEITVIDFPLPDAAHINALITKSVSPEQLKITGLAREQLIKACQGLSRTRIQRVLARALADKQQVNETDIESVLDEKKQAIRQTGILEFLPARESLKNVGGLDNLKTWVRMRNDVFSEEARRYGIPNPKGVLLVGIQGTGKSLSAKTIAHEWRLPLLRLDTGRLFGGIVGESESRLRQMIQLAEAMSPCVLWIDEIDKAFGNISGGTDGDSGTSRRVFGTLITWMQEKTAPVFIVATANNVRILPAELLRKGRFDEIFFLNLPTETERREIFKVHLMRLRPSRLREFDLGLLARQTNNFSGAEIEQVIIDGMHRAFGGKTTEKRRDFTTEDILRASEETVPLAAIARYQIEELKHWAAEAGARTASNDTELTEELKQWSIQKGMDSLDSD

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_052315810.1|6942853_6945442_+	PAS domain S-box protein	A0A1V0SGX0	Hokovirus	2.3e-14	27.5
WP_044196048.1|6945422_6945638_-	hypothetical protein	NA	NA	NA	NA
WP_015151548.1|6945940_6947122_+	hybrid sensor histidine kinase/response regulator	W8CYF6	Bacillus_phage	6.1e-23	31.5
WP_015151549.1|6947291_6949004_+	response regulator	W8CYF6	Bacillus_phage	5.4e-20	24.4
WP_015151550.1|6949195_6950830_+	AAA family ATPase	U5XJW0	Phormidium_phage	2.5e-152	56.2
WP_015151551.1|6950877_6951252_+	DUF1257 domain-containing protein	U5XJG2	Phormidium_phage	5.5e-10	32.1
WP_015151552.1|6951505_6951913_+	DUF1257 domain-containing protein	NA	NA	NA	NA
WP_015151553.1|6951973_6953551_-	Hsp70 family protein	A0A2P1ELB9	Moumouvirus	1.0e-17	24.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage
NC_019693.1|WP_015151332.1|6663878_6664100_+|hypothetical-protein	6663878_6664100_+	73 aa aa	NA	NA	NA	No	NA

Protein sequences of NC_019693.1|WP_015151332.1|6663878_6664100_+|hypothetical-protein

>NC_019693.1|WP_015151332.1|6663878_6664100_+|hypothetical-protein
MNPNRDLQTAKPHQVNYRDWTILVFPGTDGYRPLCLASETEVLSDPKPYPTPEVAIAAGKRFIDRAIGHQEVA