CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NC_020056	Anabaena cylindrica PCC 7122 plasmid pANACY.05, complete sequence	0 crisprs	NA	0	0
NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	5 crisprs	cas3,cas6,WYL,csx1,cas10,csm3gr7,csx10gr5,csx19,cas7,cas5,cas4,cas1,cas2,Cas9_archaeal,Cas14c_CAS-V-F,cmr3gr5,cmr4gr7,cmr5gr11,cmr6gr7,RT	118	0
NC_019774	Anabaena cylindrica PCC 7122 plasmid pANACY.04, complete sequence	0 crisprs	NA	0	0
NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	3 crisprs	cmr6gr7,cmr5gr11,cmr4gr7,cmr3gr5,cas10,cas2,cas1,csx18,WYL	40	0
NC_019771	Anabaena cylindrica PCC 7122, complete sequence	23 crisprs	c2c5_V-U5,cas14k,c2c9_V-U4,csa3,cas2,cas1,cas4,cas6,csc1gr5,csc2gr7,cas10d,PD-DExK,cas3,WYL,DinG,2OG_CAS,RT,DEDDh,cas14j,csx3,cas10,csm3gr7,csx10gr5,csm2gr11,csm6,csx19,csx21	17	5
NC_020157	Anabaena cylindrica PCC 7122 plasmid pANACY.02, complete sequence	0 crisprs	PD-DExK,csa3,cmr1gr7,cmr6gr7,cas10,cmr4gr7,cmr5gr11,cmr3gr5	0	0
NC_019775	Anabaena cylindrica PCC 7122 plasmid pANACY.06, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_019773_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019773_1

1994-2536

TypeIII-C

A:N

Consensus_repeat	Method
CTTTACAAAACCACTTCCCCGCAAGGGGATGGAAAC	PILER-CR
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	CRISPRCasFinder
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	CRT

7 spacers

The CRISPR arrays of NC_019773_1

>merge|NC_019773|1|1994-2536|PILER-CR,CRISPRCasFinder,CRT
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAGGTTCTTGCAACAATTCCTTCAATATCTATCTACTAAGTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAGATTACAAAATCCAGCCTCAAAAAAATTAATAAGGAAACAGAAAGTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAGGGCTTTTCTGGAGTATTGGTGATAAATAATTATGGTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAGGACTCAATTGAATATCACCTAATTGAACTTACGTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAGATTTTTCGGGCTGGAACTTACCACCCACCAACGATGGTGTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAGACAATCCTAGTGATAACAACGAACCCGTATCAAAAGTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAGACCTTCCGCTTTTACGGAAATTGATAAACAAACCCCCGTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG

>NC_019773|1|1|1994-2536|PILER-CR
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	GTTCTTGCAACAATTCCTTCAATATCTATCTACTAA
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	ATTACAAAATCCAGCCTCAAAAAAATTAATAAGGAAACAGAAA
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	GGCTTTTCTGGAGTATTGGTGATAAATAATTATG
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	GACTCAATTGAATATCACCTAATTGAACTTAC
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	ATTTTTCGGGCTGGAACTTACCACCCACCAACGATGGT
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	ACAATCCTAGTGATAACAACGAACCCGTATCAAAA
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	ACCTTCCGCTTTTACGGAAATTGATAAACAAACCCCC
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG

>NC_019773|1|1|1994-2536|CRISPRCasFinder
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	GTTCTTGCAACAATTCCTTCAATATCTATCTACTAA
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	ATTACAAAATCCAGCCTCAAAAAAATTAATAAGGAAACAGAAA
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	GGCTTTTCTGGAGTATTGGTGATAAATAATTATG
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	GACTCAATTGAATATCACCTAATTGAACTTAC
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	ATTTTTCGGGCTGGAACTTACCACCCACCAACGATGGT
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	ACAATCCTAGTGATAACAACGAACCCGTATCAAAA
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	ACCTTCCGCTTTTACGGAAATTGATAAACAAACCCCC
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG

>NC_019773|1|1|1994-2536|CRT
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	GTTCTTGCAACAATTCCTTCAATATCTATCTACTAA
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	ATTACAAAATCCAGCCTCAAAAAAATTAATAAGGAAACAGAAA
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	GGCTTTTCTGGAGTATTGGTGATAAATAATTATG
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	GACTCAATTGAATATCACCTAATTGAACTTAC
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	ATTTTTCGGGCTGGAACTTACCACCCACCAACGATGGT
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	ACAATCCTAGTGATAACAACGAACCCGTATCAAAA
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG	ACCTTCCGCTTTTACGGAAATTGATAAACAAACCCCC
GTTTCCATCCCCTTGCGGGGAAGTGGTTTTGTAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019773.1\|WP_015217699.1\|1540_1732_+\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217704.1\|7220_7973_-\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|212001
NC_019773.1\|WP_015212319.1\|5855_7076_-\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NC_019773.1\|WP_081593770.1\|4559_4748_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225082
NC_019773.1\|WP_015217701.1\|3576_3906_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217697.1\|76_823_+\|ParA-family-protein	unknown	unknown	gnl\|CDD\|224113
NC_019773.1\|WP_015217702.1\|4100_4484_-\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NC_019773.1\|WP_015217703.1\|4823_5594_-\|DUF559-domain-containing-protein	unknown	unknown	gnl\|CDD\|238509
NC_019773.1\|WP_015217700.1\|2944_3505_+\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_042466412.1\|8845_9430_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217707.1\|9737_10175_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217705.1\|8001_8634_-\|deoxynucleoside-kinase	unknown	unknown	gnl\|CDD\|223203

Protein	Function_ID	Function_description	E-value
NC_019773.1\|WP_015217704.1\|7220_7973_-\|radical-SAM-protein	gnl\|CDD\|212001	TIGR04278, viperin-like_protein, antiviral radical SAM protein viperin. Viperin (Virus Inhibitory Protein, ER-associated, Iterferon-inducible) is a radical SAM enzyme found in human and other vertebrates. It is both induced by interferon and demonstrably active in blocking replication by several types of virus, apparently by modifying lipid chemistries in lipid droplets and membrane rafts.	1.63298e-50
NC_019773.1\|WP_015212319.1\|5855_7076_-\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.27075e-100
NC_019773.1\|WP_081593770.1\|4559_4748_-\|hypothetical-protein	gnl\|CDD\|225082	COG2171, DapD, Tetrahydrodipicolinate N-succinyltransferase [Amino acid transport and metabolism].	0.000292087
NC_019773.1\|WP_015217702.1\|4100_4484_-\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	2.62732e-21
NC_019773.1\|WP_015217703.1\|4823_5594_-\|DUF559-domain-containing-protein	gnl\|CDD\|238509	cd01038, Endonuclease_DUF559, Domain of unknown function, appears to be related to a diverse group of endonucleases.	1.84123e-05
NC_019773.1\|WP_015217705.1\|8001_8634_-\|deoxynucleoside-kinase	gnl\|CDD\|223203	COG0125, Tmk, Thymidylate kinase [Nucleotide transport and metabolism].	3.40698e-14
NC_019773.1\|WP_015217697.1\|76_823_+\|ParA-family-protein	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	3.35018e-68

>NC_019773.1|WP_015217699.1|1540_1732_+|hypothetical-protein
MKNTELELSQEELKLARDWIKDCGWGDIEDEDVDDLTDKQVEKAVQKFYDGGINSFKNDAQHF
>NC_019773.1|WP_015217697.1|76_823_+|ParA-family-protein
MIIALANQKGGVAKTTSTICLGGLLAKHSNVLAIDLDPQGNLTTGLGVEVADDQISCYDVITEQAEVMDAVVPTNCGLNLLPADINLAKGETEILTKIGNFYILKEKLVPVLSQFQHVLIDCPPSLGLLTVNALAAADVVLIPVQCQFFALKGLAALLETVASVQKRLNPQLQILGVLPTMAENTVMTQDVLASLRKRLQDIHVFDPVPKSIKFSESNLAGEPIHIYAKESKLVQPYQKIAKLITGKK
>NC_019773.1|WP_015217700.1|2944_3505_+|hypothetical-protein
MEQLSLFSNTEHLSPGARKEKPVMDAQALIQWKSRIFTYQQHIRNSQAPQQTSLFDLTPYHCDPDTIDPFNLHLQSMAFYRMPDTYGQAALYFIVDSAAEILLYIGETCQSNKRWKNTHDCKEYIGSYQELHYKYDMTTAVNIGFWWDAPIDRKPRQALEQKMIQTWRSPFNKEMWDLWGQPFQHS
>NC_019773.1|WP_015217701.1|3576_3906_-|hypothetical-protein
MFKGFGRKKKPVLGDNELFTGITQHPVTGRWQTWISFTGNDIQCITAHNNQDDADKVARAIADAWREGKYKTSEETTAFIKSLPTDGPIDPLPQNIVMQLSKQVFNSRK
>NC_019773.1|WP_015217702.1|4100_4484_-|DoxX-family-protein
MLKKYIPLVARSFLAVIFIYTGLNKVFNFSQTSESMAKAGLPIVGVLLVFTIAFQILGGLSIILGYKAEIGAILLIIFLIPATIVFHNPFADPSQFNNFFKNLSIIGGLLLVLTYGSGSLSLDQSER
>NC_019773.1|WP_081593770.1|4559_4748_-|hypothetical-protein
MIHNLNMTDTEYTQLAAQLGETQQEARKLTRIVGLTKDKSPETDNEEIYAILHFSSYRCTPK
>NC_019773.1|WP_015217703.1|4823_5594_-|DUF559-domain-containing-protein
MSEAQKPLTKFNPSGEEQNLNASAIVVQSSRLKYFIELRTTTLIDYMLKIYTTSTSAYTRKSISDWLNIRNKPGFYKELSPNLHLAYGDQRDGHGSQHWWKLFFNEDYKPSILIHIKIEINLVKSQNSPDDSNSQYQWGGLNFRSKTEVRIAHALHSQRILFFANSRAYMDLTDLPISNSDNQSKERVEIDFLVFHKQKCMILEVDGVHHQEASQKTRDYRRDRVLLRDGIRTVRFDAGECYNRPIDVVMEFLNLF
>NC_019773.1|WP_015212319.1|5855_7076_-|ISL3-family-transposase
MKFSVDQILNLPEMKVLDFQELVGAGIIITIEKAVNYSTCPDCEKTTYSIHQNHWRLIHDLSWSEKPVLLRINRRQFKCNKCKKVFSEKLNFVDKSKGYTKRLAIDIVAQVLDSNIHSVAERNDLSDEEVESMLKAQVSQILNINLNQVKRLGIDEIALVKGQGSYLAVLVDLDTRKPIELVKSRRIEEIREVIVKWGSQVLEQIVEVSMDLWSPYKSLVEELMPNANITADRFHVMKQVNDELDAMRKSEKRAAMSLDNKSERDRILAGLNKSKYSLIKNEDSLNEQQKERLNNVQKVSPILAKMHALKEEFRDIFESTKSWGESIMNLLDWMHDGLSYFPKSIGTMIRWFGEVVGYFDGRTTSGTVEGINNKLKLIKRLGYGFRNFSNFRLRSLLNWHFSINSP
>NC_019773.1|WP_015217704.1|7220_7973_-|radical-SAM-protein
MKPISVNFHLWKPCNYHCRFCFATFPDIEGALTLNDAKHLLFLLREAGAEKLNFAGGEPTLHPNIGELVAESHRLGFITSLVSNGARMNQLLEKHANEMDWVALSVDSASEVIQKNLGRGNGNHVIQSIALFDKLHQYSIRVKLNTVVTNLNYQENMSAFVRRVRPERWKIFQVLPVQGQNDGSVEELLISPQQFQEFVERHQPLINEGFQVIPESNDLMKDSYIMVNPQGQFYNITKDNGLLRLFYGEN
>NC_019773.1|WP_015217705.1|8001_8634_-|deoxynucleoside-kinase
MKKFPFLAFEGLDGAGKTTLAELFAKQQNFDYYGSIPPELISLRKQIAATNSPISTFHFYSLCNILRSYEYRLKLNDLGVVADRYVFSTFAYHSLLMKQDLSSYLHILQSEQNFLLPDVIVYVTASQSTINQRITQRSQKVPMQWYGDKVSLEYNLDESYKRIFSLVNIPIVQIDTTNSNPEQAYSNLCCELYKIKDTIPILKTISFNID
>NC_019773.1|WP_042466412.1|8845_9430_-|hypothetical-protein
MNLLTKFKHFRKINYLGLLMISACTPASSQGQLFTYREGNFSIFMPGAIPEETTTAIQGITVRTWTTVKNESLYTVAHSKFANKIAPDKRQQVLQVLINAATKTNFSKGKKLSQTAVNKDGYNCQDFSLTGEPSVSVQGEAKKTGLNIKSKLYYQRNMLCIKDDQVVEAVVFTPSDEELKNNGASFIKSLNLKP
>NC_019773.1|WP_015217707.1|9737_10175_-|hypothetical-protein
MKLIHDEEVIVEICSNQLVLTTHRIRYQTEIYGNVELTSIMLEEIASCSLVRKNHASLLVMALLLTFIGIGPLVTMTEGILIMYLIIMIDVILVVIYLVIRHPVILITSAGESIKLRITTMKLDAVLNFINTVEIMKNERYFMNR

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Crispr_ID: NC_019773_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019773_2

23460-25825

TypeIII

A:N

Consensus_repeat	Method
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	PILER-CR
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CRISPRCasFinder
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CRT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	PILER-CR

31 spacers

cas10,cmr3gr5,cmr4gr7,cmr5gr11,cmr6gr7,cas2,cas1,csx18,WYL

The CRISPR arrays of NC_019773_2

>merge|NC_019773|2|23460-25825|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATTCTAAAGCAGTGCAATCTGTCGCAACTTCAATTAAAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATAATATAGTCACAATCTACCTTTCACACAAGTAGAGTGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATTAGAAACCTTTACAGCTAAAGATAAAGAGCTATCTGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATCTGATTGACATCGGGTTATGTGAAGATAACACGGAAGAATAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATTAGATGAACTTGTAAACTTTGGTAGTAAATCACATGATGGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATCCACGTCATCCATGCTGGCTCGTAGGTGGAGAGAGATAGCAACTAGGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATTTGGCAAGTAGTTCAAACTGGTCAAATCAGTGTTGAAGATCCAATTACTAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATAAACAATCATCATCTACATCATCATATTTGAAATAACCAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATTCTGTTTGTTGTAGCTTACAAGCTACTCTACAAATTAGAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATTTATCCGAGTCTTCAATACGTCTTTTTGTCAACAAAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATTTAATACTAGCTTAATTCTTACTAAAGAGTCATTTTACGGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATTAGGTGATGTACCATTACTTGAACAAACTAAATTTGGCAAAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATCATCAAGCAGGACATCATGTAACTTTTGAAAATCGAAAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATAATAGTGGTTTAATCCAACTGTGTACGTTCTCATCTGGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATGGAAGTATTCTAAAACTACAAAGTGAAGCTTATTCTAAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATAAGATGACACTCTACAAGGGTTATAAGCTCCATTCATCAAAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATCCTTTTAGCACAATAACTGTAATAGTTTCTGCTACTGATGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATCTGACATTATCAGACAAGTTGAACAGCGTGAAATGGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATTCTACGCAGAGTCAGGTAAAGTCTCTTATTTTCAAGGTGGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATCTACCACCAAAGACCAATCAAGTTAGACCTGAGCATTCTACAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATCATATTAAGGCATCTTCTTGGGACGGATTAAACCAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATTGGAGTGTCTCACCATTCTCGGTAGCTACTGCCTCGGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATACTTTATCACGGTACTATCTGAGGACTTGATGTGGGAGGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATGATTGTTGCTTTTTAGGTATAGACGATGATGAGATAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATGTTAAGGACGCGGTTATGACTAACGAAAAATCAAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATTGATGATGTACTGGTAGTTAGTTTACCTGCTCAATCTATGGGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATGTGTAAACTGCTTTATCTGGTAATTCATTTAATAGTTGTTTGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATGAAAGCGGTAAGTTCGATGCTCAACATTTACGAATAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATTTGTGATCAGTAGAATCAGCTAAGTCCTCATCTAGCTGCCGTAAATAGTGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATTCTGCAAAAATGGCTGCTGAAGAATCAATTGATTACGACGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATTAGCCCTCTTCCCTACTCCCCCTAGTTATCCTCGATCCATCTGGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT

>NC_019773|2|2|23460-25514|PILER-CR
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TCTAAAGCAGTGCAATCTGTCGCAACTTCAATTAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	AATATAGTCACAATCTACCTTTCACACAAGTAGAGT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TAGAAACCTTTACAGCTAAAGATAAAGAGCTATCT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CTGATTGACATCGGGTTATGTGAAGATAACACGGAAGAATA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TAGATGAACTTGTAAACTTTGGTAGTAAATCACATGATG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CCACGTCATCCATGCTGGCTCGTAGGTGGAGAGAGATAGCAACTAG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TTGGCAAGTAGTTCAAACTGGTCAAATCAGTGTTGAAGATCCAATTACTA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	AAACAATCATCATCTACATCATCATATTTGAAATAACCA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TCTGTTTGTTGTAGCTTACAAGCTACTCTACAAATTAGA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TTATCCGAGTCTTCAATACGTCTTTTTGTCAACAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TTAATACTAGCTTAATTCTTACTAAAGAGTCATTTTACG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TAGGTGATGTACCATTACTTGAACAAACTAAATTTGGCAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CATCAAGCAGGACATCATGTAACTTTTGAAAATCGAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	AATAGTGGTTTAATCCAACTGTGTACGTTCTCATCTG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GGAAGTATTCTAAAACTACAAAGTGAAGCTTATTCTAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	AAGATGACACTCTACAAGGGTTATAAGCTCCATTCATCAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CCTTTTAGCACAATAACTGTAATAGTTTCTGCTACTGAT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CTGACATTATCAGACAAGTTGAACAGCGTGAAATG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TCTACGCAGAGTCAGGTAAAGTCTCTTATTTTCAAGGTG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CTACCACCAAAGACCAATCAAGTTAGACCTGAGCATTCTACA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CATATTAAGGCATCTTCTTGGGACGGATTAAACCA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TGGAGTGTCTCACCATTCTCGGTAGCTACTGCCTCG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	ACTTTATCACGGTACTATCTGAGGACTTGATGTGGGAG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GATTGTTGCTTTTTAGGTATAGACGATGATGAGATA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GTTAAGGACGCGGTTATGACTAACGAAAAATCAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TGATGATGTACTGGTAGTTAGTTTACCTGCTCAATCTATGG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GTGTAAACTGCTTTATCTGGTAATTCATTTAATAGTTGTTT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATGAAAGCGGTAAGTTCGATGCTCAACATTTACGAATAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TTGTGATCAGTAGAATCAGCTAAGTCCTCATCTAGCTGCCGTAAATAGT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TCTGCAAAAATGGCTGCTGAAGAATCAATTGATTACGAC
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TAGCCCTCTTCCCTACTCCCCCTAGTTATCCTCGATCCATCTG


>NC_019773|2|2|23460-25825|CRISPRCasFinder
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TCTAAAGCAGTGCAATCTGTCGCAACTTCAATTAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	AATATAGTCACAATCTACCTTTCACACAAGTAGAGT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TAGAAACCTTTACAGCTAAAGATAAAGAGCTATCT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CTGATTGACATCGGGTTATGTGAAGATAACACGGAAGAATA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TAGATGAACTTGTAAACTTTGGTAGTAAATCACATGATG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CCACGTCATCCATGCTGGCTCGTAGGTGGAGAGAGATAGCAACTAG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TTGGCAAGTAGTTCAAACTGGTCAAATCAGTGTTGAAGATCCAATTACTA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	AAACAATCATCATCTACATCATCATATTTGAAATAACCA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TCTGTTTGTTGTAGCTTACAAGCTACTCTACAAATTAGA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TTATCCGAGTCTTCAATACGTCTTTTTGTCAACAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TTAATACTAGCTTAATTCTTACTAAAGAGTCATTTTACG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TAGGTGATGTACCATTACTTGAACAAACTAAATTTGGCAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CATCAAGCAGGACATCATGTAACTTTTGAAAATCGAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	AATAGTGGTTTAATCCAACTGTGTACGTTCTCATCTG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GGAAGTATTCTAAAACTACAAAGTGAAGCTTATTCTAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	AAGATGACACTCTACAAGGGTTATAAGCTCCATTCATCAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CCTTTTAGCACAATAACTGTAATAGTTTCTGCTACTGAT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CTGACATTATCAGACAAGTTGAACAGCGTGAAATG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TCTACGCAGAGTCAGGTAAAGTCTCTTATTTTCAAGGTG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CTACCACCAAAGACCAATCAAGTTAGACCTGAGCATTCTACA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CATATTAAGGCATCTTCTTGGGACGGATTAAACCA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TGGAGTGTCTCACCATTCTCGGTAGCTACTGCCTCG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	ACTTTATCACGGTACTATCTGAGGACTTGATGTGGGAG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GATTGTTGCTTTTTAGGTATAGACGATGATGAGATA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GTTAAGGACGCGGTTATGACTAACGAAAAATCAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TGATGATGTACTGGTAGTTAGTTTACCTGCTCAATCTATGG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GTGTAAACTGCTTTATCTGGTAATTCATTTAATAGTTGTTT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GAAAGCGGTAAGTTCGATGCTCAACATTTACGAATA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TTGTGATCAGTAGAATCAGCTAAGTCCTCATCTAGCTGCCGTAAATAGT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TCTGCAAAAATGGCTGCTGAAGAATCAATTGATTACGAC
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TAGCCCTCTTCCCTACTCCCCCTAGTTATCCTCGATCCATCTG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT

>NC_019773|2|2|23460-25825|CRT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TCTAAAGCAGTGCAATCTGTCGCAACTTCAATTAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	AATATAGTCACAATCTACCTTTCACACAAGTAGAGT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TAGAAACCTTTACAGCTAAAGATAAAGAGCTATCT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CTGATTGACATCGGGTTATGTGAAGATAACACGGAAGAATA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TAGATGAACTTGTAAACTTTGGTAGTAAATCACATGATG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CCACGTCATCCATGCTGGCTCGTAGGTGGAGAGAGATAGCAACTAG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TTGGCAAGTAGTTCAAACTGGTCAAATCAGTGTTGAAGATCCAATTACTA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	AAACAATCATCATCTACATCATCATATTTGAAATAACCA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TCTGTTTGTTGTAGCTTACAAGCTACTCTACAAATTAGA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TTATCCGAGTCTTCAATACGTCTTTTTGTCAACAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TTAATACTAGCTTAATTCTTACTAAAGAGTCATTTTACG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TAGGTGATGTACCATTACTTGAACAAACTAAATTTGGCAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CATCAAGCAGGACATCATGTAACTTTTGAAAATCGAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	AATAGTGGTTTAATCCAACTGTGTACGTTCTCATCTG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GGAAGTATTCTAAAACTACAAAGTGAAGCTTATTCTAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	AAGATGACACTCTACAAGGGTTATAAGCTCCATTCATCAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CCTTTTAGCACAATAACTGTAATAGTTTCTGCTACTGAT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CTGACATTATCAGACAAGTTGAACAGCGTGAAATG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TCTACGCAGAGTCAGGTAAAGTCTCTTATTTTCAAGGTG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CTACCACCAAAGACCAATCAAGTTAGACCTGAGCATTCTACA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CATATTAAGGCATCTTCTTGGGACGGATTAAACCA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TGGAGTGTCTCACCATTCTCGGTAGCTACTGCCTCG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	ACTTTATCACGGTACTATCTGAGGACTTGATGTGGGAG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GATTGTTGCTTTTTAGGTATAGACGATGATGAGATA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GTTAAGGACGCGGTTATGACTAACGAAAAATCAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TGATGATGTACTGGTAGTTAGTTTACCTGCTCAATCTATGG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GTGTAAACTGCTTTATCTGGTAATTCATTTAATAGTTGTTT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GAAAGCGGTAAGTTCGATGCTCAACATTTACGAATA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TTGTGATCAGTAGAATCAGCTAAGTCCTCATCTAGCTGCCGTAAATAGT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TCTGCAAAAATGGCTGCTGAAGAATCAATTGATTACGAC
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TAGCCCTCTTCCCTACTCCCCCTAGTTATCCTCGATCCATCTG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT

>NC_019773|2|3|25551-25825|PILER-CR
	TCTAAAGCAGTGCAATCTGTCGCAACTTCAATTAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	AATATAGTCACAATCTACCTTTCACACAAGTAGAGT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TAGAAACCTTTACAGCTAAAGATAAAGAGCTATCT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CTGATTGACATCGGGTTATGTGAAGATAACACGGAAGAATA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TAGATGAACTTGTAAACTTTGGTAGTAAATCACATGATG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CCACGTCATCCATGCTGGCTCGTAGGTGGAGAGAGATAGCAACTAG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TTGGCAAGTAGTTCAAACTGGTCAAATCAGTGTTGAAGATCCAATTACTA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	AAACAATCATCATCTACATCATCATATTTGAAATAACCA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TCTGTTTGTTGTAGCTTACAAGCTACTCTACAAATTAGA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TTATCCGAGTCTTCAATACGTCTTTTTGTCAACAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TTAATACTAGCTTAATTCTTACTAAAGAGTCATTTTACG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TAGGTGATGTACCATTACTTGAACAAACTAAATTTGGCAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CATCAAGCAGGACATCATGTAACTTTTGAAAATCGAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	AATAGTGGTTTAATCCAACTGTGTACGTTCTCATCTG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GGAAGTATTCTAAAACTACAAAGTGAAGCTTATTCTAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	AAGATGACACTCTACAAGGGTTATAAGCTCCATTCATCAAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CCTTTTAGCACAATAACTGTAATAGTTTCTGCTACTGAT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CTGACATTATCAGACAAGTTGAACAGCGTGAAATG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TCTACGCAGAGTCAGGTAAAGTCTCTTATTTTCAAGGTG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CTACCACCAAAGACCAATCAAGTTAGACCTGAGCATTCTACA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	CATATTAAGGCATCTTCTTGGGACGGATTAAACCA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TGGAGTGTCTCACCATTCTCGGTAGCTACTGCCTCG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	ACTTTATCACGGTACTATCTGAGGACTTGATGTGGGAG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GATTGTTGCTTTTTAGGTATAGACGATGATGAGATA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GTTAAGGACGCGGTTATGACTAACGAAAAATCAA
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TGATGATGTACTGGTAGTTAGTTTACCTGCTCAATCTATGG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	GTGTAAACTGCTTTATCTGGTAATTCATTTAATAGTTGTTT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAATGAAAGCGGTAAGTTCGATGCTCAACATTTACGAATAGTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TTGTGATCAGTAGAATCAGCTAAGTCCTCATCTAGCTGCCGTAAATAGT
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TCTGCAAAAATGGCTGCTGAAGAATCAATTGATTACGAC
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT	TAGCCCTCTTCCCTACTCCCCCTAGTTATCCTCGATCCATCTG
GTTTCCATTCAATTAATATCCCCAGCGAGTGGGAAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019773.1\|WP_015217712.1\|12764_14165_-\|MotA/TolQ/ExbB-proton-channel-family-protein	unknown	unknown	gnl\|CDD\|376576
NC_019773.1\|WP_015217725.1\|29260_29575_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217715.1\|17739_18138_-\|hypothetical-protein	cmr5gr11	cls000022_cmr5gr11_CAS-III-B	unknown
NC_019773.1\|WP_015217722.1\|27307_27583_-\|hypothetical-protein	csx18	cls000006_csx18_CAS-I:CAS-III	unknown
NC_019773.1\|WP_015217714.1\|15772_17734_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl\|CDD\|187792
NC_019773.1\|WP_015217723.1\|27799_28987_+\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NC_019773.1\|WP_015217724.1\|29057_29246_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217716.1\|18165_18942_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	gnl\|CDD\|224255
NC_019773.1\|WP_015217721.1\|26300_27293_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_019773.1\|WP_015217709.1\|10718_10877_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217717.1\|18953_20090_-\|CRISPR-associated-protein,-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl\|CDD\|187879
NC_019773.1\|WP_171815845.1\|31298_32594_+\|ISNCY-family-transposase	unknown	unknown	unknown
NC_019773.1\|WP_015217713.1\|14243_15776_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217720.1\|26009_26291_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_019773.1\|WP_015217728.1\|30756_30978_+\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217727.1\|30395_30749_+\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217710.1\|11585_12281_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217726.1\|29697_30399_+\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217711.1\|12298_12760_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217718.1\|20089_23125_-\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl\|CDD\|378863

Protein	Function_ID	Function_description	E-value
NC_019773.1\|WP_015217712.1\|12764_14165_-\|MotA/TolQ/ExbB-proton-channel-family-protein	gnl\|CDD\|376576	pfam01618, MotA_ExbB, MotA/TolQ/ExbB proton channel family. This family groups together integral membrane proteins that appear to be involved translocation of proteins across a membrane. These proteins are probably proton channels. MotA is an essential component of the flageller motor that uses a proton gradient to generate rotational motion in the flageller. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane.	0.000554164
NC_019773.1\|WP_015217714.1\|15772_17734_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl\|CDD\|187792	cd09661, Cmr6_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	2.58217e-18
NC_019773.1\|WP_015217723.1\|27799_28987_+\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	2.60363e-10
NC_019773.1\|WP_015217720.1\|26009_26291_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	7.61683e-30
NC_019773.1\|WP_015217716.1\|18165_18942_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	3.48673e-33
NC_019773.1\|WP_015217721.1\|26300_27293_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.88038e-113
NC_019773.1\|WP_015217718.1\|20089_23125_-\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|378863	pfam12469, DUF3692, CRISPR-associated protein. This domain family is found in bacteria and archaea, and is typically between 101 and 138 amino acids in length. The proteins in this family are frequently annotated as CRISPR-associated proteins however there is little accompanying literature to confirm this.	7.29788e-44
NC_019773.1\|WP_015217717.1\|18953_20090_-\|CRISPR-associated-protein,-Cmr3	gnl\|CDD\|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	6.79485e-62

>NC_019773.1|WP_015217718.1|20089_23125_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MSEEYWRAKIWGLLHDPVLKALHDNTGRGKNSFYEQLEVMKPWVEIGKTPDDSGGKALANILLADHVASASDRSAIGGTTAYVNYAEGNNPDKGLQIRHLLSGAKQDLKVKFHQQLINGKRAEFLFTKEDELLAKIPKLLKQEDIENNIPKIKQLYWWLWRCLPQVTCDIFTDSSLMLMPAETRIPDASIWSHVSMTAALAGGFAGYDLTLDEIKNWPRKKPVSHPYLAVFSFTPVQELIKSSRKMRDFWAGSWLLHYLSAKVCWKLANQYGPDTLLYPSLYQQPLIDHWLVQKYPEFAEFIGETSPELLLTAGFPNVIALVLPEDKVQAAMQTAQQTLLEEWLKIGDLVLEELQHERHWMKSLDPNHTTWKGWLKSQWQTYWTALPIGKPGTEFKCSANENKNQEFESWSKAQNETYNLINNNNRLFKEQEKDLLQESYRVRQQKYKRGFSANIGSWWGYIFDATRDSLASVKNARNWELPTAFGPRSTISGIGSVVSPGKDGKDWMTEGDTKKLWKHRAGFFDGTEQLNATEVLKRGLHKILPHLLGIENLEISYPDLTSGVAGYLKVNQSNPDHKRKFDSACQAIVDKYPEIEDILIEMRGKWGIPWIDKKQNPKKYHPRLLNAGWILEDLPNNDELKEEYTTEINEIISKHYPSNNPSDWYVLAAGDGDSMSEWLKGTKLKTYSDYIPDGFAEKVATATTPLTQFPEFLKLTKRMGPSTHSALSRALLDFSNQLVPYLTQTRYAGRLIYGGGDDVLAYTNLWEWDKWLWDIRQCFRGAEDPFKLSADNQGKYFDNPGDYWSWSGDRSPLPEGIHDRPLFTMGSAATISFGIVIAHHSVPLAIALESLWDAEDAAKKHEYHHGCELPSEKRGQKDCFNKKDAVQVRVLYGNGNTLKSTAKFDVFHQWQQLIKGDLDSAIFEQAASLWSQHPAPSQEAIKPWTKLFCDRRDQFQTDKTAKEQFQIALADFLTALFSTTQTKNLDTEIQNWLKLAAFVKRNRHIKLGGDN
>NC_019773.1|WP_015217717.1|18953_20090_-|CRISPR-associated-protein,-Cmr3
MHWYKLTPLDILMLRDAKPFSPQQRAWAGSVFPPNGHTIAGALRGLLGGGEFDITGSFLSYENTLYLPRPLGFAGSIDLVPLVWEKKSYINNALWDETQPCPLVKPYNAKDEDEEDEENQNNPLQKCVGSSEAKFRQYLPYEVVKEYLESGRINKEDWQAIEGRHEDKPYAIETRSHNSIEPGTKQVKDADGYFVENAIRLHQNWGFAIGINEKIETPATIRLGGEGHRVILESCPELGEQWQELQQLSDNNFNHDDKAIAYLVTPGVFERPHTDKHKNRINLCRPYPWEWKIKDGNFVGMATDKPVPISCRIRAKEDKTSIPAPQVFAAPPGSLYYLNKPQGLFQDNKRLENDKENRVNNWRKLGYSEMLWIKYQNN
>NC_019773.1|WP_015217716.1|18165_18942_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MEYIYLYLLSPLHTGGTTQEGNLLGIARESHTNLPYIPSSTVRGKVRSLATNEDLKHQLFGNELKDGQQLEQGNIWIGDASILWLPVPSLSHSVVWVSCPLLLQRWQRLQGGKLSIPSEYSCNFNNGAAVYLKDAIIKAEQLQSGNSLEQFVPQSDSTKSINRLLVLPDKHCATLIQMSLWRQVKIKLDAHKSVDGGFRYEEAIPPDTLMYLPWGITSQANGTSQKSYDNFKNLLAANEILQIGGQESLGRGFVQQWM
>NC_019773.1|WP_015217715.1|17739_18138_-|hypothetical-protein
MTFDPRTLATPIYDGLNNLRISTNQDDTTRLRQQKSQAVELYTYLSTWGMMRLKAEEMSLPDGMMGKKQVVKKFFECLQAVSGQQNLSGEQGLATLKNLSTDDYLGLTGLGLALAQEFSFWATAIYAGVEGE
>NC_019773.1|WP_015217714.1|15772_17734_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MTFEKPKPRQLNQPNLPVVNRPNRNNPPNDNRGGNRGGHNGGNRGNGGNNNGGNGGNQPAIPSPWLNPDNEPKPHPDASFVEYLRWMRSPQNDDAIKNSTKVQILQMAEQGSKYSQRLQELTKRTELIAQSSFKVQCPWRIRVGGHRGPESILLPAFDALGIPYIPSSTLRGVARTQAIREIMAQQNLEWKDAEKQIAPWFGYLDAKNPGDRSGKVVFLDAYPLPLQNQNVLAVDMANNIWQWENNSPRYSPNPNPFLSLEKPMFMIGLRLASNCQDNGILEKVKQWLINGLQAGVGSQVNTGYGQLNPAGKLENNGEFLRVKFILEGQLIHGQQKFRNINQPYRIANNGNIKTDTINHAEVRPVAFKSMLRYWFRSFVLGVLEPGIVQTWENQIFGGINPTKQYGWLMVRVLEGKITQKEAQNQNDKVGSQEGILTLKYSPEIPEFQKRNLQKLIKNLAWLMFHLGGIGQGARRPCYSRQNNQYAPWWRGSTLIPESEDSFWELPETTQQFQKLFRQRIEAFYQALQSLSVNFNYRQLRSCGTVNSFTWFEALDINAKIIVVKNNNSNKGYALNTLHQHFHQLENTNYTEAKNLCGGVKKDFPNKVKREVVPSPIWIADLDDYQVVTVFGATENPRRKYLETLQNKLQIFPL
>NC_019773.1|WP_015217713.1|14243_15776_-|hypothetical-protein
MKTTNNTDKVSTLIITVGTRQIGWRCKDGVIRSFGADGNIGYPAHVNELYQELGIERGNHQEGDKVYPWSGRDLGKRYYDYCKEWLGRDFSNVELLLDKIIIETAVNQGLKHIILWATDQPEDVSWFYRRLDTLYLAELIKGKIKSLFPDIRVDIHAPKINANDTLAIREELEQLVLKEALDAFYPQKNEEFTLWIQNKGCAPAVASCVEICAAALVRQCKVYNASPDEPPEFFSQLDNGLKTANHSQSFQLIPMGEYFWALEKVKIKSAWERGDFAEAQIWLKVHQTRHSVLYKLAGFLAQYSNWESNDDFYRKLKDWVGSKDVLKLVNTEQIEIWKTQLQKLQNDKITNLWESTLILELTLNRENYTTAFIQFVQILEQLLYLQSINQKWYTKGWIPKGKDEPTLAELMQGWCLYKKFKEDNKWSKLMGDIRQNRNQIIHEGESVNAKQVGDIWAKHNFEGVKIPTTPEIIKKLMINTLKEISTPPNFHNLLMRSLYQWGLQYLEDAS
>NC_019773.1|WP_015217712.1|12764_14165_-|MotA/TolQ/ExbB-proton-channel-family-protein
MTAKSLNFSPKSERQELDVKLWLILAIGLIVTLGIYVAVLPVKNTFLGTLLYERGFTQILAIFLGGMVMTITVLKFTKIQLESKAFSKDLLPGNILLENPKSVQVEKLQQSLSSEKSLLARRCNRVIAAYIASGNKQIATEFAMEDSAFYSSTAETSYSVARILVWAIPLLGFIGTVVGISGAVNGFSGFLQQSSDIEQIKQGIGTVTSGLAVAFDTTLLALFVSVLVMIPLVLVERQESRLLLAIDIYINDRLLPRLKAAESLDKTIVDDAISQAFQKHLPSPEVLIKPAQEYAKQAADALAQGFLSEVGKIHGTTNKLIQQMSYINQMAVKDRENFISTLAQQEQSSQKIVQEIQQISTAIQDNYQSVNHNFTEHTEHISEGIQKAAMSLDSRIAALENCAVQVARIVEFQQSLEQSLQTLEKTAQLEQVLGEVRTNLALLKPVLEQLNKPRRITLVEAEEKRS
>NC_019773.1|WP_015217711.1|12298_12760_-|hypothetical-protein
MPKRITKRSATEIELFPFLSVLACTIGVLILLIIVLMAQTFSSQRQVTIVAKTENGQNQSKQPRYIECRSDGIVLYPSEEFVSLTSLSLSYSSLQTLLTEVKTNRDKQYLIVAIRPDGIEVFKAIRTLIESEGIDIGYEPIDEGWTLKIEGNI
>NC_019773.1|WP_015217710.1|11585_12281_-|hypothetical-protein
MRRKRYFVSQRPQQNLDSFLDILTNTVGVLMFISLFITLVAVQSSTIVRTPLAKETDKKVNFFEITGSRVIYLDTKSANKQIKDFLGNLPECTKPSYVSGFIDSYLDELKNYQICVRNQLQELKEFRAETKNYEIELVDLESISWQYNPKPVNSGESGTELTQTNSEYRKILSQLEPDKEYLAFLVRPDSFATFRQAREIAWKAGFDVGWEPQTPETPIIFGSGGRTVGVQ
>NC_019773.1|WP_015217709.1|10718_10877_-|hypothetical-protein
MNKYRLLEIAEYISIFATLAGSTIAVTTGQIIYATVPMALALLLNLVRRSQF
>NC_019773.1|WP_015217720.1|26009_26291_-|CRISPR-associated-endonuclease-Cas2
MFLYVIAYDIPCNKRRKKVADLLEGYGQRVQYSVFECQLNTEKYQNLRRQLRKKLKLEEDNVRFYPLSRHTLSQVETWGVGIPVIEPPSSIII
>NC_019773.1|WP_015217721.1|26300_27293_-|CRISPR-associated-endonuclease-Cas1
MQTLYVSEQNCYVCLQKETLLVKQGETVYAEVQLPLLEQILIFGRSQITTQVIRACLWRDIPIAYLSRMGYCYGRILPISRGYRQLSRYQQQLSPVERLITARAMIQGKLKNSRVLLRRQRKKRESEVLERVLQSLDYLADQTAQADTWERLMGFEGAGAAQYFSAFSECLTNPDFVFSGRSRRPPGNPVNAMLSFGYQVLWNHLLALIEIQGLDPYYACLHQANDGHAALASDLIEEFRAPFIDSLVMWLINRKIVNAEADFEFKNGGCYLNDEGRKKFLRAFLQRMSEEIQTDEGIKQPKWDLLTQQVRAFKQFVYNPSHHYKPYRID
>NC_019773.1|WP_015217722.1|27307_27583_-|hypothetical-protein
MYISRRSATVRNVSVSTINGGITLVILLIAPLGLSAVIINTMLIAVATYLVSSAADRVILWLDPEQNAELTSSTESEHRSARKSNLQRWWR
>NC_019773.1|WP_015217723.1|27799_28987_+|WYL-domain-containing-protein
MPKKPAHPYTERLAFERLLLLIATLLKYPGIGSPDFLDSSNNESHNAISSVKVYLQQLATELDIELPAGYPAISTLRKDLETLRRYAILDQRMYRWGYYLGTGALSTTELKVAFNAIASQAQYQGDAQVRRIYEILSKRLRGLDMELKGEFFYPTRQHLNRAIIHTDPEEMVTKGENRDTLFHQLPLVEKAISKGEAIEISRSNDFYGFNRTGRIQVFPLQLIYHDIAWYLLYEYCENGHLAIGRLNRFNNHCKFLKMLPRGLEKQRENLAKAHKLLENGWGLNLGEPEPQKLELEGTLKFINAKVRFFPPISAFILEGERRHLYQKITSGLIDKTGQHTYIEYAVDLPPRSLNEFSLWVYRYMDKAEVLSPPQLVEQHRQSTQALFDRYFHTNR
>NC_019773.1|WP_015217724.1|29057_29246_-|hypothetical-protein
MFTKVHLVIVIEHTTLLVFYTESDCWQFRLISAGGSVFGEQKLYYTPEAAEKAGREWIYQGS
>NC_019773.1|WP_015217725.1|29260_29575_-|hypothetical-protein
MSTTSIIHPLHYLIVKREGTTWYFKPGNSVFYNPKNVPVNLALGDRLHRFGLTPQIIMIELFRINGGKAGFYLADLQDKQYYYCGTDLQDVNYRLHCLGIGSAD
>NC_019773.1|WP_015217726.1|29697_30399_+|hypothetical-protein
MDKYLFEQNRTSARKPTDIKETPEGFLAIEFTESKLISSSQQQQNSIISWIIALPLILIFGYLFAVALLAFGSILLLIFIVAFSFNRSYRNHIFAQFRIFPGEVFLSTYPLSLGEKCLLTFRRRLKRNKKTKESGQLALKIICLERVEYKKGTDTEVEINILWESQPEVYSVPTNTEVFSLQTNLNIPKYLPPSFEGKNNQIRWIISIEQNIPNIAEQVHSNFVFIVAPVVLA
>NC_019773.1|WP_015217727.1|30395_30749_+|hypothetical-protein
MIRFYFDADVDSLEVSSDLTGSCTWIPDGKNKENSLTLTIGWRTEGRGSIDSEIIYETELIQSETTYFKCKIPVAGPISYDGKLLRIIWEIVVSRRKWLGKDTLKTQIVRVIPQQKR
>NC_019773.1|WP_015217728.1|30756_30978_+|hypothetical-protein
MSYSDPYHRLGLHRNPFIAPDNLEIPSQRWFDFGFSQPPSRMKRLFWQVIGEKGAGKTSHLLHWQRPAILILK
>NC_019773.1|WP_171815845.1|31298_32594_+|ISNCY-family-transposase
MQFLHSLLHDLPDERKPGNNTKYKVEDAVMAAFSVFFTQSPSFLEHQRLMKSNKGKDNAESLFSIEAIPSDNQIRNLLDPVPANTIFMAFDKVYHWLEKNGVLKKFLYLDGEILVALDGTEYFSSQKINCPHCNCRNHRNGTTTYFHGCVTPVVVSPNQKQVINLSPEFIKKQDGHQKQDCENAAVKRWLNNNGQNKYGYPVTLLGDDLYSRQPVCELALKQGYNFIFVCLETSHKTLYEWLEFLERSGEVTTVEKKQWDGRKNLIYRYRYASRVPLRDGDSSLEANWCEVTVINEKTQKTIYKNNWLTNHKITENNVEEIVKAGRSRWKIENEGNNVLKNHGYNLEHNFGHGQNHLCEFLLSLNLLAFLFHTVLDLVNSTYQKIRELLATRTAFFNDIRTLLKFIWFKNWSEFFLFILTEYVPLTKGNSS

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Crispr_ID: NC_019773_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019773_3

82988-83125

Orphan

A:N

Consensus_repeat	Method
GGCGATAGCAGCGATGGCAATGGC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_019773_3

>merge|NC_019773|3|82988-83125|CRISPRCasFinder
GGCGATAGCAGCGATGGCAATGGCTCCGCCGATGTCGATAGCGATAGCCATTGCCATCGCAATGGCGATGGCAGCGATGGCAATGGCAGCGATAGCAATGGCTCTGCCGAAGGCGACGGCACCAGCGATGGCACCAGC

>NC_019773|3|3|82988-83125|CRISPRCasFinder
GGCGATAGCAGCGATGGCAATGGC	TCCGCCGATGTCGATAGCGATAGCCATTGCCATCGCAAT
GGCGATGGCAGCGATGGCAATGGC	AGCGATAGCAATGGCTCTGCCGAAGGC
GACGGCACCAGCGATGGCACCAGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019773.1\|WP_015217786.1\|89764_90358_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217778.1\|80695_81499_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224117
NC_019773.1\|WP_042466449.1\|69342_69756_-\|thermonuclease-family-protein	unknown	unknown	gnl\|CDD\|214615
NC_019773.1\|WP_015217787.1\|90428_91103_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015213538.1\|75270_76242_+\|ExeA-family-protein	unknown	unknown	gnl\|CDD\|225806
NC_019773.1\|WP_085930373.1\|73634_75281_+\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|366234
NC_019773.1\|WP_015217784.1\|88177_89593_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217788.1\|91271_92120_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217776.1\|79466_79904_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217770.1\|69981_70626_+\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015213536.1\|73060_73630_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
NC_019773.1\|WP_015217789.1\|92123_92549_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217774.1\|77544_78186_-\|dTMP-kinase	unknown	unknown	gnl\|CDD\|234814
NC_019773.1\|WP_015217783.1\|87810_88122_+\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217782.1\|86689_87550_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271177
NC_019773.1\|WP_085930392.1\|83594_83816_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217781.1\|85698_86550_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271177
NC_019773.1\|WP_015217775.1\|78200_79454_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217773.1\|76473_77523_-\|hypothetical-protein	unknown	unknown	unknown
NC_019773.1\|WP_015217780.1\|84236_85154_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_019773.1\|WP_015217774.1\|77544_78186_-\|dTMP-kinase	gnl\|CDD\|234814	PRK00698, tmk, thymidylate kinase; Validated.	3.84818e-47
NC_019773.1\|WP_015217778.1\|80695_81499_-\|hypothetical-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0.00153422
NC_019773.1\|WP_042466449.1\|69342_69756_-\|thermonuclease-family-protein	gnl\|CDD\|214615	smart00318, SNc, Staphylococcal nuclease homologues.	3.29647e-26
NC_019773.1\|WP_015213538.1\|75270_76242_+\|ExeA-family-protein	gnl\|CDD\|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	6.42874e-53
NC_019773.1\|WP_015217781.1\|85698_86550_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.65291e-08
NC_019773.1\|WP_085930373.1\|73634_75281_+\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	7.90591e-10
NC_019773.1\|WP_015217782.1\|86689_87550_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.03861e-09
NC_019773.1\|WP_015213536.1\|73060_73630_+\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	1.04102e-57

>NC_019773.1|WP_015217778.1|80695_81499_-|hypothetical-protein
MSQPLENLEPQQPNVNSEQEADNSTTNNKIQGDHNRTIQGNDNKAVIGDSNTVNYVSDKKNLFQIGRNYIRHIQVNILSGNWGNAIVALSPFLVLSILSGGIGFGGGVTVQDSRITNELKTAKENVIKANSEISELKERILNQTSLLKQIDDLKNQLTANRNSLNEAQRNLRITETQKIGLEKQINNLNRELIAIKKRLDGDKRSSISPSNQNGNLLGQTPLLKKSKSDCLRLTEMIEHFAKLGASTSSMKEEFKEWNCSQWGISSP
>NC_019773.1|WP_015217776.1|79466_79904_-|hypothetical-protein
MEPLILAATAIATTILTKAFEKTGEKLGEKVVEQSGRFLTSLKDKSPATAHAIELSPKQPLDYGQTVLEVNALANADPEIAREVEILAELALQENNPRLEQTIQEIQRTLQLQQPTVQVLGKLAEKIGLVVQSGGRVSIQNFHMD
>NC_019773.1|WP_015217775.1|78200_79454_-|hypothetical-protein
MTKNIEGIANKIGIYAPQGQISIENLILEQGVSQRTSVESEKTLHTAFIDQARDIHPSKGIGVSRIRKNIFLDVFDPDSRLTLGISKDLNAREHYGLLAKTLNVSVFLCDDFVILPPAFLLECPLVFKLLKSTSVFMEEGLIRLPIRDRSFSDFYEKKLEEYSEVVENYPTMFSKMGIQAVNWVKKYSHSRIERNAKIGQELAQIWAEGPDTNPYWKKHISLIPSEILEVVRQLPLNLHGRGKAITWGLVAKEIPYNQTGMPVRVTQKLIQNGYIALYLDEYDLKVVSNLPFSQDSFGHGLNNLPYDYEALRAALKPLNLFDLILNLLPEELLLLRYLAGYSRFIDVFDRIAYECESVSQIRKYFAIAASNCSSKIQQSKLDLEKINKERLNLRSHVSQEIVYLIDAILLEASLALS
>NC_019773.1|WP_015217774.1|77544_78186_-|dTMP-kinase
MKYLGKYIAIEGIDGVGKTTQAQLLKNWFEYLDIPLFTTRELSDGLIGKFSRDLLHQGLYLPPRTLALLWASDTQHNQEKTEGVVSHLNEGKYVLSDRCYLSAYAYLFPECETSWISELHKFCLIPDITIFLDLDPEIALKRIEKRNEKLHEFETLASLIRIRENYLTLIKLLKDTWKQIEIIKLNESTSIDELQQAIRQGISRYLVYTNTTK
>NC_019773.1|WP_015217773.1|76473_77523_-|hypothetical-protein
MSIFQNFFNLDIEGGEQLSGVLKLDSAINAQGASEELSYRSGKVIVGDRAVELSLVHSTASEKLVYLHKARVNHQLSDLLGLQQELGSELLLPGQLLLGSARTQVMGACTRDAVRNPSLVQIISENKPDKIAIFPIFREGIRYQVAEAIYAVYGNFYNEIMVDAHHVADKSIPGYNRRVGSVKFFDRDVTDEEMSKVNTAIIADSISGGVVLLGVLEALQQRCPNLSRIEVIAQFATLRGLARLAAYTPPRFSIRVHAFETILHSLAPNYYYAAHFMEPEMHIAPHLESEYQDWWGEDRDGKKISSSLCAGFGWSFVYFTPEKQVQVINKYLQEIHKMSLVDIINRNMR
>NC_019773.1|WP_015213538.1|75270_76242_+|ExeA-family-protein
MLTEVMEHFRLLREFRKAGYYETEHQKQLFKDIKVAIHSGKLVAITGIIGCGKTTTLRRLFEVLEKEGKILVSKSLSVDKNRATLPTLIAALFYDLATDKEIKIPALGEKRERELRDLIRKGKKPVALFVDEAHDLHYSTLTGLKRLIEVVEDGGGTLSVVLAGHPKLKNDLRRPTMEEIGYRATVFSLEGIVGSQKEYIEWLVSKCTTEDTQISEILEPDAIELLAMRLRTPLQIEQHLTLAFEAAYLFGEKTVTTAIIESILSKQIDDLEPTLTRHGYDVRGLAEQFNAKPAEIKLLFRGQLDPARSRELHEQMLAAGLPL
>NC_019773.1|WP_085930373.1|73634_75281_+|DDE-type-integrase/transposase/recombinase
MSVEALINLRHRLDGLPSRCQERRILIEETAALYGVSTDTLYRALRNSSRPKSINRSDSGTPRKLSLAEMERYCEVIAAMKIRTSNKKGRHISTVRAIELLEEFGMETPDGFVQPDKGALTRSTVNYYLKTWGYDQERMTRQPPAVRFQAEYSNECWHFDLSPSDLKHVKQPSWVEPGRGNPLLMLYSIVDDRSGLCYQEYHCVYGEDVEAALRFLFNAMTAKTTDGFAFQGIPEMIYTDNGPIAKSHVFQNVMDCLRINLVTHMPAGKDGRRVTARSKGKVERPFRTVKEAHETLYHFHEPESDIEANLWLRQYLLHYNDKPHRIEPHSRLEDWLRNIPKSGLRSMCSWERFCTFAREPQRRKVGTDARVSVEGVAYEVEPDLAGETVVLWWGLFDNELYVEKEDRRYGPFYPVDGPIPLHRYRKFKKTKTEERADKIANLAKKLGLPRTALDKNTDLQFLVDKYKELEPTVTPFNDPDPYQEFTYPTVLFAKRAISEQLAKPLAKLSPEQLAFIDALLAETLNKKAIIERVRQYFRSNQGEEQNAH
>NC_019773.1|WP_015213536.1|73060_73630_+|recombinase-family-protein
MLIGYARISTDDQNLNLQMDALQLAGCEKIYSDRTSGAKAERPGLSLALEVARTGDVLVVWRLDRLGRSLKDLIEMMETLDKRGIGLSSLQESITTTNNSGRLIFHLFGALAEFERNLIRERTTAGLVAARGRGHRGGRPKALDPTKRQLAVRLYTEKQYTIIEICNLMGISKPTLYNYIAEIKTEHGT
>NC_019773.1|WP_015217770.1|69981_70626_+|hypothetical-protein
MKNRLNSLVGLGLLGAIASLGFMPQAIAIPYNSNTVYKTVSEGVTTVYISGTPSGTASVALGFIDRFSSRVAGSCGEVRLSATTVGATPTVQVGSPGVSVEIENLPVQLLPTCTSGSFAEARPNNFKTPSGEVVIVGQTANTAVLLNIPRDTTRTVRLNACGFGTLRNTSSFSIPPTFSVEGVEKTLATLPNAGNAPRCTSGVGYVPSAWIGGT
>NC_019773.1|WP_042466449.1|69342_69756_-|thermonuclease-family-protein
MRDGDTIKVKKNGVIENIRLCGIDAPEISQPLGKESRDYLRSVFSLKKMVQISTVGTDRYNRKIGEVFLINSDGTEKFLNEELVKAGMAYVYHQYSKNCPNEISLKNGEAMAQSKKIGVWSRNYQKPWEYRKAKRSK
>NC_019773.1|WP_085930392.1|83594_83816_-|hypothetical-protein
MGYIGEKRSHLAEYEELEKAVTHKWILSTAKVKELIGVTPRVGKDEMTFVWGSFTFTKAGKLGNQMGWLVSKS
>NC_019773.1|WP_015217780.1|84236_85154_+|hypothetical-protein
MTKKQPPLATFRCDEQLWQDFKDLCSKNNTNASAALIAFVKQSVASGNLDINAQAYRQITPTQSILLNLDDIYKYIDNRLDNIDAQSRRDTDTQISTQNLEELIDSRILLSVLNGDIKEANARSYSQATTNLNSTRKEFYSKVEELEKQLEELKSNPPVAVAVPLIPQSPITSEELPETTSPAVVLNHQSPEDRRYSKIVDWVCAQLNLGRLISDHFGSIDPITNQPCGELFDNEYLIEHNFHGQIAARKDELELRLGIILTGSKARVTSDVKAILTALGFQFGHKQIKKKETYWVINPQNEKNL
>NC_019773.1|WP_015217781.1|85698_86550_+|tyrosine-type-recombinase/integrase
MKIDGCGQAKILSGQERELLLNKGFLSQRDRTLNELCFYTACRSCEARQILYSDIFNGDKIRETLILRKEITKGKQATRVIPVNPKLALSLEKYIQESQELLKIKQLVGQWDYKSLTCNDVFDENNQIICPKCSHNVISTAGKSRGKQLYKCKKCAYRFLVKTAFVESPELKDRVLQLGVYNSQSYGFLFANSSNPYLFPGDQGNGSISRTTVKEIFANACKRVGIIGAGTHSWRRTALTEMHKKKIPMKVIQNISGHVRLSNLQKYLEVSREEVEAAINSLP
>NC_019773.1|WP_015217782.1|86689_87550_+|tyrosine-type-recombinase/integrase
MLINRNGQAKVLTKSEIQQLFHNGFKSSRDKALFAVAFYTACRISEARKMFIIDAFYDGKVRDEIIIRKAHSKGKQGTRSIPTHPNLKKILQEYYDNSAKLVEMKKMIGDWSEKSFNCEGKIIINLAHQCPRCQFAGIFKNGVCNNQQRYKCKKCRHEFFERELPKTDLASENSSAIEFDPLGVTCSTLYGFLLEKSDNPFLFPGRRSKGYISLRNAMSIFVYAFDKLGIDGASTHSCRRTALTMMHREGVILKVLQEISGHKDLGALQKYLEVSEEQARAAINIL
>NC_019773.1|WP_015217783.1|87810_88122_+|hypothetical-protein
MGTSGRGGKREGGGRPSNWQYQPTCTIRVPKIFAEILLKTAQELDKGLNEIIIVDPKKMSVSPQVKKEVLSLSQLRIYTREGHKTLRLEELISVLQQCLKQKD
>NC_019773.1|WP_015217784.1|88177_89593_-|hypothetical-protein
MQEIQQFNQQLVKQRRSSTALVGILLMSGFIASVPMFSDSIKHQETLYCNVKSSCRPSKIKRGISFLVDRERRNQLFDNNINVVKILPPEDPTAITWGLFSSLFLLSAYGVNKTLTNHQEKSIHSQFKLLKIKALENDLLEQTHIDLFGFSKSNQAEITKQVIARHTAESIQAMKSEGEVQLDHLNGQLQGTLSIKTHQLQVSELDKETAKNELEIAEIKRKLDKLNKPVSDAKQPSANEELKTVLIDALKGHEDGYLWKIISSLKPLWLIGNQGSGKTYTAGAIALIRKYCLDADIYYLIDRHATGINAKVWKFLQSQNIAENEQDTMTAFQDLIRYWMDRIKQNPSNKTQTIIDEFTHQRMLIGELADTVFKLSLSDTRKAKNMLLGITHNDTNESFAPGTEATRKAGMILLQKFSADGDTPLPRVVVRYGLVDAQGNELKDVEHTLPSWVHPEKIHQHFNGKPIDFDS
>NC_019773.1|WP_015217786.1|89764_90358_-|hypothetical-protein
MLTQSPNDLDNILDSEETPLQGETVRYLTHIENKLYADIQARKRIDSSLLFLACQISSCSLSWLLFNLQVTLTIIQVASAVVSLLPGLIDVGDSFNFSISSDSWEFSLGNKPLIGIVKLAIGGAVSFSGTSKITSEIIQTKQAIAQTYQEIRSSDGLSFQLPDMGFSLLIALSSIALLGILKKVANPNNNQENNSND
>NC_019773.1|WP_015217787.1|90428_91103_-|hypothetical-protein
MKQLPPAKTPKLKNHVLPKGKLITKVLGKKFGVTLSDFDKAMGGDIAAAQKIGELARQGRLSQELAPKLAQAYLEIINGSEAYNKATADILLQAGKSAIAIDKAASQVMLGQQKYIHQRQELAQEFVLSKNTENTRHNYQMNYTQIKGYIDAHLVGVDQQAAILEQSNRPENKQIAADEQLQSKQISQALDKGENARYDLIPEKQYHTPGFKERFMQFKAALGF
>NC_019773.1|WP_015217788.1|91271_92120_-|hypothetical-protein
MLTIVAKRVQSRLSRKGLKVELKDVKTYLQNNVSNVNNITDRETNKATDYFMSTATKLTVIQEDVEPMITNESAPELEALTNNNSDELEPTQETSICVDVENGNIAELTQEELETLTSEDVDTVNRVDDVNTASIQDIDSSELYTNRPALDTEEETALATATKSELIASTANSLGVVLNTAEIELIASNFNSSSEDLTDSLEEIKSAIVAFIQYKVSLNSQKISETLEEISQVASDGFSQNSEQLTTGLQGINSQLQEQTKDFKSKVKSTLAAFKIPSLKAG
>NC_019773.1|WP_015217789.1|92123_92549_-|hypothetical-protein
MENERAIYETVTGARVNDVHWWRVKRDMRTAELPLTKDGFELFIALRKTSPRYFSQYHKIKGKISKVESSIGDGCTGQQFINLLEKLGITPNKGTISRWFKTAGGFKAKSFYAKQVLIPICAVALIYKSKVQSSQLSKIGA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_019773_1	1.1\|2030\|36\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	2030-2065	36	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	2030-2065	0	1.0
NC_019773_1	1.2\|2102\|43\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	2102-2144	43	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	2102-2144	0	1.0
NC_019773_1	1.3\|2181\|34\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	2181-2214	34	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	2181-2214	0	1.0
NC_019773_1	1.4\|2251\|32\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	2251-2282	32	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	2251-2282	0	1.0
NC_019773_1	1.5\|2319\|38\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	2319-2356	38	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	2319-2356	0	1.0
NC_019773_1	1.6\|2393\|35\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	2393-2427	35	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	2393-2427	0	1.0
NC_019773_1	1.7\|2464\|37\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	2464-2500	37	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	2464-2500	0	1.0
NC_019773_2	2.1\|23496\|36\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	23496-23531	36	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	23496-23531	0	1.0
NC_019773_2	2.2\|23568\|36\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	23568-23603	36	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	23568-23603	0	1.0
NC_019773_2	2.3\|23640\|35\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	23640-23674	35	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	23640-23674	0	1.0
NC_019773_2	2.4\|23711\|41\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	23711-23751	41	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	23711-23751	0	1.0
NC_019773_2	2.5\|23788\|39\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	23788-23826	39	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	23788-23826	0	1.0
NC_019773_2	2.6\|23863\|46\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	23863-23908	46	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	23863-23908	0	1.0
NC_019773_2	2.7\|23945\|50\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	23945-23994	50	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	23945-23994	0	1.0
NC_019773_2	2.8\|24031\|39\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	24031-24069	39	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	24031-24069	0	1.0
NC_019773_2	2.9\|24106\|39\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	24106-24144	39	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	24106-24144	0	1.0
NC_019773_2	2.10\|24181\|36\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	24181-24216	36	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	24181-24216	0	1.0
NC_019773_2	2.11\|24253\|39\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	24253-24291	39	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	24253-24291	0	1.0
NC_019773_2	2.12\|24328\|41\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	24328-24368	41	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	24328-24368	0	1.0
NC_019773_2	2.13\|24405\|38\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	24405-24442	38	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	24405-24442	0	1.0
NC_019773_2	2.14\|24479\|37\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	24479-24515	37	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	24479-24515	0	1.0
NC_019773_2	2.15\|24552\|38\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	24552-24589	38	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	24552-24589	0	1.0
NC_019773_2	2.16\|24626\|41\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	24626-24666	41	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	24626-24666	0	1.0
NC_019773_2	2.17\|24703\|39\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	24703-24741	39	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	24703-24741	0	1.0
NC_019773_2	2.18\|24778\|35\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	24778-24812	35	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	24778-24812	0	1.0
NC_019773_2	2.19\|24849\|39\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	24849-24887	39	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	24849-24887	0	1.0
NC_019773_2	2.20\|24924\|42\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	24924-24965	42	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	24924-24965	0	1.0
NC_019773_2	2.21\|25002\|35\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	25002-25036	35	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	25002-25036	0	1.0
NC_019773_2	2.22\|25073\|36\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	25073-25108	36	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	25073-25108	0	1.0
NC_019773_2	2.23\|25145\|38\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	25145-25182	38	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	25145-25182	0	1.0
NC_019773_2	2.24\|25219\|36\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	25219-25254	36	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	25219-25254	0	1.0
NC_019773_2	2.25\|25291\|34\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	25291-25324	34	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	25291-25324	0	1.0
NC_019773_2	2.26\|25361\|41\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	25361-25401	41	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	25361-25401	0	1.0
NC_019773_2	2.27\|25438\|41\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	25438-25478	41	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	25438-25478	0	1.0
NC_019773_2	2.28\|25515\|36\|NC_019773\|CRISPRCasFinder,CRT	25515-25550	36	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	25515-25550	0	1.0
NC_019773_2	2.29\|25587\|49\|NC_019773\|CRISPRCasFinder,CRT,PILER-CR	25587-25635	49	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	25587-25635	0	1.0
NC_019773_2	2.30\|25672\|39\|NC_019773\|CRISPRCasFinder,CRT,PILER-CR	25672-25710	39	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	25672-25710	0	1.0
NC_019773_2	2.31\|25747\|43\|NC_019773\|CRISPRCasFinder,CRT,PILER-CR	25747-25789	43	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	25747-25789	0	1.0
NC_019773_3	3.1\|83012\|39\|NC_019773\|CRISPRCasFinder	83012-83050	39	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	83012-83050	0	1.0
NC_019773_3	3.2\|83075\|27\|NC_019773\|CRISPRCasFinder	83075-83101	27	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	83075-83101	0	1.0
NC_019773_3	3.2\|83075\|27\|NC_019773\|CRISPRCasFinder	83075-83101	27	NC_019773	Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence	82997-83023	4	0.852
NC_019773_1	1.4\|2251\|32\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	2251-2282	32	NC_018878	Bacillus thuringiensis Bt407 plasmid BTB_502p, complete sequence	145639-145670	6	0.812
NC_019773_1	1.3\|2181\|34\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	2181-2214	34	NZ_CP019309	Phaeobacter inhibens strain DOK1-1 plasmid pDOK1-1-2, complete sequence	80242-80275	9	0.735
NC_019773_1	1.4\|2251\|32\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	2251-2282	32	MN855750	Bacteriophage sp. isolate 168, complete genome	9064-9095	11	0.656
NC_019773_1	1.4\|2251\|32\|NC_019773\|PILER-CR,CRISPRCasFinder,CRT	2251-2282	32	MN855975	Siphoviridae sp. isolate 45, complete genome	29164-29195	11	0.656

1. spacer 1.1|2030|36|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

gttcttgcaacaattccttcaatatctatctactaa	CRISPR spacer
gttcttgcaacaattccttcaatatctatctactaa	Protospacer
************************************

2. spacer 1.2|2102|43|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

attacaaaatccagcctcaaaaaaattaataaggaaacagaaa	CRISPR spacer
attacaaaatccagcctcaaaaaaattaataaggaaacagaaa	Protospacer
*******************************************

3. spacer 1.3|2181|34|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

ggcttttctggagtattggtgataaataattatg	CRISPR spacer
ggcttttctggagtattggtgataaataattatg	Protospacer
**********************************

4. spacer 1.4|2251|32|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

gactcaattgaatatcacctaattgaacttac	CRISPR spacer
gactcaattgaatatcacctaattgaacttac	Protospacer
********************************

5. spacer 1.5|2319|38|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

atttttcgggctggaacttaccacccaccaacgatggt	CRISPR spacer
atttttcgggctggaacttaccacccaccaacgatggt	Protospacer
**************************************

6. spacer 1.6|2393|35|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

acaatcctagtgataacaacgaacccgtatcaaaa	CRISPR spacer
acaatcctagtgataacaacgaacccgtatcaaaa	Protospacer
***********************************

7. spacer 1.7|2464|37|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

accttccgcttttacggaaattgataaacaaaccccc	CRISPR spacer
accttccgcttttacggaaattgataaacaaaccccc	Protospacer
*************************************

8. spacer 2.1|23496|36|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

tctaaagcagtgcaatctgtcgcaacttcaattaaa	CRISPR spacer
tctaaagcagtgcaatctgtcgcaacttcaattaaa	Protospacer
************************************

9. spacer 2.2|23568|36|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

aatatagtcacaatctacctttcacacaagtagagt	CRISPR spacer
aatatagtcacaatctacctttcacacaagtagagt	Protospacer
************************************

10. spacer 2.3|23640|35|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

tagaaacctttacagctaaagataaagagctatct	CRISPR spacer
tagaaacctttacagctaaagataaagagctatct	Protospacer
***********************************

11. spacer 2.4|23711|41|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

ctgattgacatcgggttatgtgaagataacacggaagaata	CRISPR spacer
ctgattgacatcgggttatgtgaagataacacggaagaata	Protospacer
*****************************************

12. spacer 2.5|23788|39|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

tagatgaacttgtaaactttggtagtaaatcacatgatg	CRISPR spacer
tagatgaacttgtaaactttggtagtaaatcacatgatg	Protospacer
***************************************

13. spacer 2.6|23863|46|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

ccacgtcatccatgctggctcgtaggtggagagagatagcaactag	CRISPR spacer
ccacgtcatccatgctggctcgtaggtggagagagatagcaactag	Protospacer
**********************************************

14. spacer 2.7|23945|50|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

ttggcaagtagttcaaactggtcaaatcagtgttgaagatccaattacta	CRISPR spacer
ttggcaagtagttcaaactggtcaaatcagtgttgaagatccaattacta	Protospacer
**************************************************

15. spacer 2.8|24031|39|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

aaacaatcatcatctacatcatcatatttgaaataacca	CRISPR spacer
aaacaatcatcatctacatcatcatatttgaaataacca	Protospacer
***************************************

16. spacer 2.9|24106|39|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

tctgtttgttgtagcttacaagctactctacaaattaga	CRISPR spacer
tctgtttgttgtagcttacaagctactctacaaattaga	Protospacer
***************************************

17. spacer 2.10|24181|36|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

ttatccgagtcttcaatacgtctttttgtcaacaaa	CRISPR spacer
ttatccgagtcttcaatacgtctttttgtcaacaaa	Protospacer
************************************

18. spacer 2.11|24253|39|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

ttaatactagcttaattcttactaaagagtcattttacg	CRISPR spacer
ttaatactagcttaattcttactaaagagtcattttacg	Protospacer
***************************************

19. spacer 2.12|24328|41|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

taggtgatgtaccattacttgaacaaactaaatttggcaaa	CRISPR spacer
taggtgatgtaccattacttgaacaaactaaatttggcaaa	Protospacer
*****************************************

20. spacer 2.13|24405|38|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

catcaagcaggacatcatgtaacttttgaaaatcgaaa	CRISPR spacer
catcaagcaggacatcatgtaacttttgaaaatcgaaa	Protospacer
**************************************

21. spacer 2.14|24479|37|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

aatagtggtttaatccaactgtgtacgttctcatctg	CRISPR spacer
aatagtggtttaatccaactgtgtacgttctcatctg	Protospacer
*************************************

22. spacer 2.15|24552|38|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

ggaagtattctaaaactacaaagtgaagcttattctaa	CRISPR spacer
ggaagtattctaaaactacaaagtgaagcttattctaa	Protospacer
**************************************

23. spacer 2.16|24626|41|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

aagatgacactctacaagggttataagctccattcatcaaa	CRISPR spacer
aagatgacactctacaagggttataagctccattcatcaaa	Protospacer
*****************************************

24. spacer 2.17|24703|39|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

ccttttagcacaataactgtaatagtttctgctactgat	CRISPR spacer
ccttttagcacaataactgtaatagtttctgctactgat	Protospacer
***************************************

25. spacer 2.18|24778|35|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

ctgacattatcagacaagttgaacagcgtgaaatg	CRISPR spacer
ctgacattatcagacaagttgaacagcgtgaaatg	Protospacer
***********************************

26. spacer 2.19|24849|39|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

tctacgcagagtcaggtaaagtctcttattttcaaggtg	CRISPR spacer
tctacgcagagtcaggtaaagtctcttattttcaaggtg	Protospacer
***************************************

27. spacer 2.20|24924|42|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

ctaccaccaaagaccaatcaagttagacctgagcattctaca	CRISPR spacer
ctaccaccaaagaccaatcaagttagacctgagcattctaca	Protospacer
******************************************

28. spacer 2.21|25002|35|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

catattaaggcatcttcttgggacggattaaacca	CRISPR spacer
catattaaggcatcttcttgggacggattaaacca	Protospacer
***********************************

29. spacer 2.22|25073|36|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

tggagtgtctcaccattctcggtagctactgcctcg	CRISPR spacer
tggagtgtctcaccattctcggtagctactgcctcg	Protospacer
************************************

30. spacer 2.23|25145|38|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

actttatcacggtactatctgaggacttgatgtgggag	CRISPR spacer
actttatcacggtactatctgaggacttgatgtgggag	Protospacer
**************************************

31. spacer 2.24|25219|36|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

gattgttgctttttaggtatagacgatgatgagata	CRISPR spacer
gattgttgctttttaggtatagacgatgatgagata	Protospacer
************************************

32. spacer 2.25|25291|34|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

gttaaggacgcggttatgactaacgaaaaatcaa	CRISPR spacer
gttaaggacgcggttatgactaacgaaaaatcaa	Protospacer
**********************************

33. spacer 2.26|25361|41|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

tgatgatgtactggtagttagtttacctgctcaatctatgg	CRISPR spacer
tgatgatgtactggtagttagtttacctgctcaatctatgg	Protospacer
*****************************************

34. spacer 2.27|25438|41|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

gtgtaaactgctttatctggtaattcatttaatagttgttt	CRISPR spacer
gtgtaaactgctttatctggtaattcatttaatagttgttt	Protospacer
*****************************************

35. spacer 2.28|25515|36|NC_019773|CRISPRCasFinder,CRT matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

gaaagcggtaagttcgatgctcaacatttacgaata	CRISPR spacer
gaaagcggtaagttcgatgctcaacatttacgaata	Protospacer
************************************

36. spacer 2.29|25587|49|NC_019773|CRISPRCasFinder,CRT,PILER-CR matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

ttgtgatcagtagaatcagctaagtcctcatctagctgccgtaaatagt	CRISPR spacer
ttgtgatcagtagaatcagctaagtcctcatctagctgccgtaaatagt	Protospacer
*************************************************

37. spacer 2.30|25672|39|NC_019773|CRISPRCasFinder,CRT,PILER-CR matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

tctgcaaaaatggctgctgaagaatcaattgattacgac	CRISPR spacer
tctgcaaaaatggctgctgaagaatcaattgattacgac	Protospacer
***************************************

38. spacer 2.31|25747|43|NC_019773|CRISPRCasFinder,CRT,PILER-CR matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

tagccctcttccctactccccctagttatcctcgatccatctg	CRISPR spacer
tagccctcttccctactccccctagttatcctcgatccatctg	Protospacer
*******************************************

39. spacer 3.1|83012|39|NC_019773|CRISPRCasFinder matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

tccgccgatgtcgatagcgatagccattgccatcgcaat	CRISPR spacer
tccgccgatgtcgatagcgatagccattgccatcgcaat	Protospacer
***************************************

40. spacer 3.2|83075|27|NC_019773|CRISPRCasFinder matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 0, identity: 1.0

agcgatagcaatggctctgccgaaggc	CRISPR spacer
agcgatagcaatggctctgccgaaggc	Protospacer
***************************

41. spacer 3.2|83075|27|NC_019773|CRISPRCasFinder matches to NC_019773 (Anabaena cylindrica PCC 7122 plasmid pANACY.03, complete sequence) position: , mismatch: 4, identity: 0.852

agcgatagcaatggctctgccgaaggc	CRISPR spacer
agcgatggcaatggctccgccgatgtc	Protospacer
******.**********.***** * *

42. spacer 1.4|2251|32|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NC_018878 (Bacillus thuringiensis Bt407 plasmid BTB_502p, complete sequence) position: , mismatch: 6, identity: 0.812

gactcaattgaatatcacctaattgaacttac	CRISPR spacer
cactcacttcaatatcacctaattgaaaatag	Protospacer
 ***** ** *****************  **

43. spacer 1.3|2181|34|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019309 (Phaeobacter inhibens strain DOK1-1 plasmid pDOK1-1-2, complete sequence) position: , mismatch: 9, identity: 0.735

ggcttttctggagtattggtgataaataattatg	CRISPR spacer
gcatttgctggagaattggtgataaataccgaca	Protospacer
*  *** ****** ************** . *..

44. spacer 1.4|2251|32|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to MN855750 (Bacteriophage sp. isolate 168, complete genome) position: , mismatch: 11, identity: 0.656

gactcaattgaatatcacctaattgaacttac	CRISPR spacer
ataccatttgaatatcacctgattgaataact	Protospacer
.  .** *************.******.   .

45. spacer 1.4|2251|32|NC_019773|PILER-CR,CRISPRCasFinder,CRT matches to MN855975 (Siphoviridae sp. isolate 45, complete genome) position: , mismatch: 11, identity: 0.656

gactcaattgaatatcacctaattgaacttac	CRISPR spacer
ataccatttgaatatcacctgattgaataact	Protospacer
.  .** *************.******.   .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_019771_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_1

57665-59539

Orphan

NA:I-D,II-B

Consensus_repeat	Method
ATTGCAATTTTCATTAATCCCTATTAGGGA----TTGAAAC	PILER-CR
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CRISPRCasFinder
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CRT
ATTGCAATTTTCATTAATCCCTATTAGGGA----TTGAAA	PILER-CR

25 spacers

The CRISPR arrays of NC_019771_1

>merge|NC_019771|1|57665-59539|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACATCAAGAAATTCGTCTGTAGCTTCTGCTGCCACATTTTATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACGAGAGAGTTGCACTTTTAAAAGGTCTTTTAGATATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACAGTGTCCAATGCTTTGTTTACCTTGTGGATTAATAGCGATCGCCAATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACCATTTATTAACCATTGATGAATTATTTCAGCGTCATCAATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACCATTTGATAACTGTGTAGGTGTGGTGAATTGCACATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACCTCAATAGCTTGCACATTGATACCTAGCCGTCTTATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACGTTTTTGGGCATCTGGCAATGGTAGGGGTTCATCTGATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACATCAAGGTAAAGTACGATTGTTATCTTATCCATATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACGGTACATCGGAAGAAACAACCGATACCAACCGCACACATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACAAATCGATAGCTGCAATCCAACCTAACGAGTTGGTAATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACCAGGTACGGTAACTTTCCGTCATGCACATCTCATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACACTTAGTTTTTCTTGCTCTGACATTTTAGCCCCTAATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACGTCCATCAGCCCAAACCTCCAAATTCACGGTAGAGTCCTTAGATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACCCCTCTGTGTACCGCCCCAAAGCTTCACGCCAACCATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACAAGCGTTCCTGGCGGACATCCTTCGATGCACTCCAATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACTTCGCCCAAGCGAGTCCAGAAGATTTTGTAATCCGTACATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACATTCATGTTTCAATCAGTTTTATAAACTCCTCATAATTGCAATTTTCATTAATCCCTAATAGGGATTGAAACCGGGCATCAAACCCAACTGATCCGATACAGCAAGCAGCAAGATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACAAATAGCTCATTCCATAAAAGCTGGGATACTGTTAAAAAAAATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACTTGAGATTTTAACTGTAGTTTCTGCCAATGCTGGGGAATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACATACGGGTGTAGCTTTCAACAACATAGAAACGCTAATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACGGGTAGGATTCGCCTGTTTCGGGGACAAAGAACGAATTTATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACACGAAAGAGGTGAAAAAAACCACCGATAAAGTAATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACGAAGAGAGCCGCCAAAATCCTGTGAAGAAGCAAAAATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACATAACTGAATCAACGAAATATTCAACGATTTTTACTATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAA

>NC_019771|1|1|57665-58362|PILER-CR
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ATCAAGAAATTCGTCTGTAGCTTCTGCTGCCACATTTT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GAGAGAGTTGCACTTTTAAAAGGTCTTTTAGAT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	AGTGTCCAATGCTTTGTTTACCTTGTGGATTAATAGCGATCGCCA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CATTTATTAACCATTGATGAATTATTTCAGCGTCATCA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CATTTGATAACTGTGTAGGTGTGGTGAATTGCAC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CTCAATAGCTTGCACATTGATACCTAGCCGTCTT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GTTTTTGGGCATCTGGCAATGGTAGGGGTTCATCTG
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ATCAAGGTAAAGTACGATTGTTATCTTATCCAT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GGTACATCGGAAGAAACAACCGATACCAACCGCACAC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACAAATCGATAGCTGCAATCCAACCTAACGAGTTGGTAATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACCAGGTACGGTAACTTTCCGTCATGCACATCTCATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CACTTAGTTTTTCTTGCTCTGACATTTTAGCCCCTA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CGTCCATCAGCCCAAACCTCCAAATTCACGGTAGAGTCCTTAG
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CCCCTCTGTGTACCGCCCCAAAGCTTCACGCCAACC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CAAGCGTTCCTGGCGGACATCCTTCGATGCACTCCA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CTTCGCCCAAGCGAGTCCAGAAGATTTTGTAATCCGTAC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CATTCATGTTTCAATCAGTTTTATAAACTCCTCATA
ATTGCAATTTTCATTAATCCCTAATAGGGATTGAAA	CCGGGCATCAAACCCAACTGATCCGATACAGCAAGCAGCAAG
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CAAATAGCTCATTCCATAAAAGCTGGGATACTGTTAAAAAAA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CTTGAGATTTTAACTGTAGTTTCTGCCAATGCTGGGGA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CATACGGGTGTAGCTTTCAACAACATAGAAACGCTA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CGGGTAGGATTCGCCTGTTTCGGGGACAAAGAACGAATTT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CACGAAAGAGGTGAAAAAAACCACCGATAAAGTA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CGAAGAGAGCCGCCAAAATCCTGTGAAGAAGCAAAA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CATAACTGAATCAACGAAATATTCAACGATTTTTACT


>NC_019771|1|1|57665-59539|CRISPRCasFinder
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ATCAAGAAATTCGTCTGTAGCTTCTGCTGCCACATTTT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GAGAGAGTTGCACTTTTAAAAGGTCTTTTAGAT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	AGTGTCCAATGCTTTGTTTACCTTGTGGATTAATAGCGATCGCCA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CATTTATTAACCATTGATGAATTATTTCAGCGTCATCA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CATTTGATAACTGTGTAGGTGTGGTGAATTGCAC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CTCAATAGCTTGCACATTGATACCTAGCCGTCTT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GTTTTTGGGCATCTGGCAATGGTAGGGGTTCATCTG
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ATCAAGGTAAAGTACGATTGTTATCTTATCCAT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GGTACATCGGAAGAAACAACCGATACCAACCGCACAC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	AAATCGATAGCTGCAATCCAACCTAACGAGTTGGTA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CAGGTACGGTAACTTTCCGTCATGCACATCTC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ACTTAGTTTTTCTTGCTCTGACATTTTAGCCCCTA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GTCCATCAGCCCAAACCTCCAAATTCACGGTAGAGTCCTTAG
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CCCTCTGTGTACCGCCCCAAAGCTTCACGCCAACC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	AAGCGTTCCTGGCGGACATCCTTCGATGCACTCCA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	TTCGCCCAAGCGAGTCCAGAAGATTTTGTAATCCGTAC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ATTCATGTTTCAATCAGTTTTATAAACTCCTCATA
ATTGCAATTTTCATTAATCCCTAATAGGGATTGAAAC	CGGGCATCAAACCCAACTGATCCGATACAGCAAGCAGCAAG
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	AAATAGCTCATTCCATAAAAGCTGGGATACTGTTAAAAAAA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	TTGAGATTTTAACTGTAGTTTCTGCCAATGCTGGGGA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ATACGGGTGTAGCTTTCAACAACATAGAAACGCTA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GGGTAGGATTCGCCTGTTTCGGGGACAAAGAACGAATTT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ACGAAAGAGGTGAAAAAAACCACCGATAAAGTA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GAAGAGAGCCGCCAAAATCCTGTGAAGAAGCAAAA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ATAACTGAATCAACGAAATATTCAACGATTTTTACT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAA

>NC_019771|1|1|57665-59539|CRT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ATCAAGAAATTCGTCTGTAGCTTCTGCTGCCACATTTT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GAGAGAGTTGCACTTTTAAAAGGTCTTTTAGAT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	AGTGTCCAATGCTTTGTTTACCTTGTGGATTAATAGCGATCGCCA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CATTTATTAACCATTGATGAATTATTTCAGCGTCATCA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CATTTGATAACTGTGTAGGTGTGGTGAATTGCAC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CTCAATAGCTTGCACATTGATACCTAGCCGTCTT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GTTTTTGGGCATCTGGCAATGGTAGGGGTTCATCTG
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ATCAAGGTAAAGTACGATTGTTATCTTATCCAT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GGTACATCGGAAGAAACAACCGATACCAACCGCACAC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	AAATCGATAGCTGCAATCCAACCTAACGAGTTGGTA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CAGGTACGGTAACTTTCCGTCATGCACATCTC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ACTTAGTTTTTCTTGCTCTGACATTTTAGCCCCTA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GTCCATCAGCCCAAACCTCCAAATTCACGGTAGAGTCCTTAG
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CCCTCTGTGTACCGCCCCAAAGCTTCACGCCAACC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	AAGCGTTCCTGGCGGACATCCTTCGATGCACTCCA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	TTCGCCCAAGCGAGTCCAGAAGATTTTGTAATCCGTAC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ATTCATGTTTCAATCAGTTTTATAAACTCCTCATA
ATTGCAATTTTCATTAATCCCTAATAGGGATTGAAAC	CGGGCATCAAACCCAACTGATCCGATACAGCAAGCAGCAAG
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	AAATAGCTCATTCCATAAAAGCTGGGATACTGTTAAAAAAA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	TTGAGATTTTAACTGTAGTTTCTGCCAATGCTGGGGA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ATACGGGTGTAGCTTTCAACAACATAGAAACGCTA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GGGTAGGATTCGCCTGTTTCGGGGACAAAGAACGAATTT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ACGAAAGAGGTGAAAAAAACCACCGATAAAGTA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GAAGAGAGCCGCCAAAATCCTGTGAAGAAGCAAAA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ATAACTGAATCAACGAAATATTCAACGATTTTTACT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAA

>NC_019771|1|2|58468-59538|PILER-CR
	ATCAAGAAATTCGTCTGTAGCTTCTGCTGCCACATTTT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GAGAGAGTTGCACTTTTAAAAGGTCTTTTAGAT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	AGTGTCCAATGCTTTGTTTACCTTGTGGATTAATAGCGATCGCCA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CATTTATTAACCATTGATGAATTATTTCAGCGTCATCA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CATTTGATAACTGTGTAGGTGTGGTGAATTGCAC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	CTCAATAGCTTGCACATTGATACCTAGCCGTCTT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GTTTTTGGGCATCTGGCAATGGTAGGGGTTCATCTG
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	ATCAAGGTAAAGTACGATTGTTATCTTATCCAT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAAC	GGTACATCGGAAGAAACAACCGATACCAACCGCACAC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACAAATCGATAGCTGCAATCCAACCTAACGAGTTGGTAATTGCAATTTTCATTAATCCCTATTAGGGATTGAAACCAGGTACGGTAACTTTCCGTCATGCACATCTCATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CACTTAGTTTTTCTTGCTCTGACATTTTAGCCCCTA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CGTCCATCAGCCCAAACCTCCAAATTCACGGTAGAGTCCTTAG
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CCCCTCTGTGTACCGCCCCAAAGCTTCACGCCAACC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CAAGCGTTCCTGGCGGACATCCTTCGATGCACTCCA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CTTCGCCCAAGCGAGTCCAGAAGATTTTGTAATCCGTAC
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CATTCATGTTTCAATCAGTTTTATAAACTCCTCATA
ATTGCAATTTTCATTAATCCCTAATAGGGATTGAAA	CCGGGCATCAAACCCAACTGATCCGATACAGCAAGCAGCAAG
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CAAATAGCTCATTCCATAAAAGCTGGGATACTGTTAAAAAAA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CTTGAGATTTTAACTGTAGTTTCTGCCAATGCTGGGGA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CATACGGGTGTAGCTTTCAACAACATAGAAACGCTA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CGGGTAGGATTCGCCTGTTTCGGGGACAAAGAACGAATTT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CACGAAAGAGGTGAAAAAAACCACCGATAAAGTA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CGAAGAGAGCCGCCAAAATCCTGTGAAGAAGCAAAA
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA	CATAACTGAATCAACGAAATATTCAACGATTTTTACT
ATTGCAATTTTCATTAATCCCTATTAGGGATTGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_150111058.1\|64378_65365_+\|DUF4437-domain-containing-protein	unknown	unknown	gnl\|CDD\|380434
NC_019771.1\|WP_015212327.1\|65958_66387_+\|GFA-family-protein	unknown	unknown	gnl\|CDD\|226314
NC_019771.1\|WP_015212329.1\|67930_68377_-\|DUF3598-family-protein	unknown	unknown	unknown
NC_019771.1\|WP_015212319.1\|61066_62287_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NC_019771.1\|WP_150111057.1\|62936_63893_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|273670
NC_019771.1\|WP_015212321.1\|56406_57420_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224213
NC_019771.1\|WP_015212316.1\|48318_48909_-\|exopolysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|226442
NC_019771.1\|WP_015212320.1\|54686_56132_+\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NC_019771.1\|WP_015212313.1\|44710_45679_-\|metal-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238557
NC_019771.1\|WP_042465531.1\|49268_50144_-\|lipid-kinase	unknown	unknown	gnl\|CDD\|183857
NC_019771.1\|WP_015212322.1\|59836_60301_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015212314.1\|45804_46632_+\|metal-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224046
NC_019771.1\|WP_015212310.1\|42842_44300_+\|S8-family-serine-peptidase	unknown	unknown	gnl\|CDD\|173799
NC_019771.1\|WP_015212323.1\|60429_60828_-\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|378915
NC_019771.1\|WP_015212330.1\|68472_69894_-\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143417
NC_019771.1\|WP_015212324.1\|62370_62940_+\|nicotinamide-mononucleotide-transporter	unknown	unknown	gnl\|CDD\|377432
NC_019771.1\|WP_015212328.1\|66502_67891_-\|histidine--tRNA-ligase	unknown	unknown	gnl\|CDD\|223202
NC_019771.1\|WP_015212319.1\|53027_54248_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NC_019771.1\|WP_015212315.1\|46845_47709_+\|metal-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224033
NC_019771.1\|WP_015212318.1\|50726_52403_-\|SulP-family-inorganic-anion-transporter	unknown	unknown	gnl\|CDD\|223732

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015212327.1\|65958_66387_+\|GFA-family-protein	gnl\|CDD\|226314	COG3791, COG3791, Uncharacterized conserved protein [Function unknown].	3.32498e-20
NC_019771.1\|WP_015212319.1\|61066_62287_+\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.27075e-100
NC_019771.1\|WP_150111057.1\|62936_63893_+\|AAA-family-ATPase	gnl\|CDD\|273670	TIGR01526, nadR_NMN_Atrans, nicotinamide-nucleotide adenylyltransferase, NadR type. The NadR protein of E. coli and closely related bacteria is both enzyme and regulatory protein. The first 60 or so amino acids, N-terminal to the region covered by this model, is a DNA-binding helix-turn-helix domain (pfam01381) responsible for repressing the nadAB genes of NAD de novo biosynthesis. The NadR homologs in Mycobacterium tuberculosis, Haemophilus influenzae, and others appear to lack the repressor domain. NadR has recently been shown to act as an enzyme of the salvage pathway of NAD biosynthesis, nicotinamide-nucleotide adenylyltransferase; members of this family are presumed to share this activity. E. coli NadR has also been found to regulate the import of its substrate, nicotinamide ribonucleotide, but it is not known if the other members of this model share that activity.	2.03033e-89
NC_019771.1\|WP_015212321.1\|56406_57420_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|224213	COG1294, AppB, Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion].	1.03412e-93
NC_019771.1\|WP_015212316.1\|48318_48909_-\|exopolysaccharide-biosynthesis-protein	gnl\|CDD\|226442	COG3932, COG3932, Uncharacterized ABC-type transport system, permease components [General function prediction only].	7.99001e-64
NC_019771.1\|WP_015212320.1\|54686_56132_+\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	0
NC_019771.1\|WP_015212313.1\|44710_45679_-\|metal-ABC-transporter-substrate-binding-protein	gnl\|CDD\|238557	cd01137, PsaA, Metal binding protein PsaA. These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence).	1.30907e-120
NC_019771.1\|WP_042465531.1\|49268_50144_-\|lipid-kinase	gnl\|CDD\|183857	PRK13057, PRK13057, lipid kinase.	0
NC_019771.1\|WP_015212310.1\|42842_44300_+\|S8-family-serine-peptidase	gnl\|CDD\|173799	cd07473, Peptidases_S8_Subtilisin_like, Peptidase S8 family domain in Subtilisin-like proteins. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	1.06314e-108
NC_019771.1\|WP_015212314.1\|45804_46632_+\|metal-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224046	COG1121, ZnuC, ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism].	1.63962e-105
NC_019771.1\|WP_150111058.1\|64378_65365_+\|DUF4437-domain-containing-protein	gnl\|CDD\|380434	cd20300, cupin_npun_f5605-like_N, Nostoc punctiforme npun_f5605 and related proteins, N-terminal cupin domain. This family includes proteins homologous to Nostoc punctiforme putative dioxygenase npun_f5605, a protein of unknown function. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	3.61622e-36
NC_019771.1\|WP_015212323.1\|60429_60828_-\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	7.69569e-10
NC_019771.1\|WP_015212330.1\|68472_69894_-\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143417	cd07099, ALDH_DDALDH, Methylomonas sp. 4,4'-diapolycopene-dialdehyde dehydrogenase-like. The 4,4'-diapolycopene-dialdehyde dehydrogenase (DDALDH) involved in C30 carotenoid synthesis in Methylomonas sp. strain 16a and other similar sequences are present in this CD. DDALDH converts 4,4'-diapolycopene-dialdehyde into 4,4'-diapolycopene-diacid.	0
NC_019771.1\|WP_015212324.1\|62370_62940_+\|nicotinamide-mononucleotide-transporter	gnl\|CDD\|377432	pfam04973, NMN_transporter, Nicotinamide mononucleotide transporter. Members of this family are integral membrane proteins that are involved in transport of nicotinamide mononucleotide.	2.189e-57
NC_019771.1\|WP_015212328.1\|66502_67891_-\|histidine--tRNA-ligase	gnl\|CDD\|223202	COG0124, HisS, Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].	2.37862e-147
NC_019771.1\|WP_015212319.1\|53027_54248_+\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.27075e-100
NC_019771.1\|WP_015212315.1\|46845_47709_+\|metal-ABC-transporter-permease	gnl\|CDD\|224033	COG1108, ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism].	3.24291e-77
NC_019771.1\|WP_015212318.1\|50726_52403_-\|SulP-family-inorganic-anion-transporter	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	1.65942e-144

>NC_019771.1|WP_015212321.1|56406_57420_+|cytochrome-d-ubiquinol-oxidase-subunit-II
METLQYFLPQVWFVILGLFLFLYVMLDGFDLGVGILSLTSSDEERRGLLMTSLSNIWDANETWLVLMAGGLFGAFPLAYGTILNALYIPILVMIFGFIFRGVAFEFRELSRRKLFWNLAFGAGSFGAALGQGFALGAVLQGINVDQKGHFIGSTWDWLSLPSVLVALTLIQGYVLIGSTYLVWKTTGELQETHYKTAKLAAWTTLIGAVLITITTPLIYEGARMRLFQQPLVYIFAVIPILGIWLIWQLLQSLNRQEERAPFVWTILLFVLTFLGLGLIVFPYIIPRQITIYEAAADPSSLVIMIIFIGFLIPVMLFYNLYQYIVFRGKVTGGEYGE
>NC_019771.1|WP_015212320.1|54686_56132_+|cytochrome-ubiquinol-oxidase-subunit-I
MEFLSDSVLLSRLQFALTAIFHMLWPVLTTGMGIYLVIIEGVWLKTRNPDYYLHARFWSKFYVLNFGIGVATGIPMEFQFGTNWAPFSEAVGNFFGSVIGFEASWAFMLEAAFLGIMLFGWERVNPTIHYLSTILVAVGANLSTLWILTANSWMQTPAGGELVDGKFIVHDYFQAILNPFMVNSVLHMFFATLETSLFVIGGISAWYILRQSHPAFFSRSLKIALAAAIAVAPLQIYIGHLSGEQVYHYQPTKLAAMEAQWESSPAGKPADWSILAIPNEKAQKNDWEITIPNALGYILEFKQNLSEPLRGLKEWKPEDRPHMIGLIYYAFRIMIGIGFFFAGLMLLSTLQWLRGKLSAENISKQRWLMVGWVLAAPLGYIAVESGWIVRCVGRQPWILYGQIRTVDAASHLPASNVLVSLTSFATVYSILFIAALYFGSRIIRNGPNLDLPIPGVEITKPAVDTTPGEFLPDERPVEAQQ
>NC_019771.1|WP_015212319.1|53027_54248_+|ISL3-family-transposase
MKFSVDQILNLPEMKVLDFQELVGAGIIITIEKAVNYSTCPDCEKTTYSIHQNHWRLIHDLSWSEKPVLLRINRRQFKCNKCKKVFSEKLNFVDKSKGYTKRLAIDIVAQVLDSNIHSVAERNDLSDEEVESMLKAQVSQILNINLNQVKRLGIDEIALVKGQGSYLAVLVDLDTRKPIELVKSRRIEEIREVIVKWGSQVLEQIVEVSMDLWSPYKSLVEELMPNANITADRFHVMKQVNDELDAMRKSEKRAAMSLDNKSERDRILAGLNKSKYSLIKNEDSLNEQQKERLNNVQKVSPILAKMHALKEEFRDIFESTKSWGESIMNLLDWMHDGLSYFPKSIGTMIRWFGEVVGYFDGRTTSGTVEGINNKLKLIKRLGYGFRNFSNFRLRSLLNWHFSINSP
>NC_019771.1|WP_015212318.1|50726_52403_-|SulP-family-inorganic-anion-transporter
MQITNTIHFRNLRGDIFGGVTAAIVSLPLALAFGVASGAGPVAGLYGAVCVGFFAALFGGTPTLISEPTGPMTVVITGIISSFTANDPENGLAMAFTVVMLAGIFQIIFGIFKLGKYITLMPYSVISGFMSGIGVILIILQIAPFLGQATPKGGVLGIVQNLPNLLGNINPIALILGVMTVAIIFLTPSKVKRIVPPQLIALVAVTVVSLVFFGDADIKRIGVIETGLPKIQLPTFTLSNVTIMLVDGVMLGMLGCIDTLLTAVVADSLTRTEHKSDKELIGQGIANVVSGLCGGLPGAGATMGTVVNIQTGAQTAVSGLTRALVLLVVVLGAAGITQSIPMAVLAGIALKVGVDILDWSFLKRSHKVSLKGSIIMYGVLLLTVFVDLIVAVGVGIFIANILTIERLSSMQSETVKAISDADDAIDLTPEEKSLLDAANGRVLLFYLSGAMIFGVSKAISREHNAIKDCDVIVLDLSDVPMMGVTASLTIESAIREACEKGRQVIIVGAAGKIKKRLDNLGVLSLLPPHHLMVDRKEALTQAVALVHSLATETNAPVS
>NC_019771.1|WP_042465531.1|49268_50144_-|lipid-kinase
MSPRALLLVNRHARKGEENLLAAIHCLESLGFNVIPESTENPTHLGDVIRQYHHEIDLVIVGGGDGTLNAAVDAVVETQLPLGILPLGTANDLARTLGIPNSLPEACQVIAAGQLQHIDLGWVNGKYFFNAASLGLSVKITQRLTTEVKRRWGIFAYAAAAFQVIWKSRPFSAEIRINGQSIHVKTVQIAVGNGRYYGGGMAVFHDATIDDQRLDLYSLEVKHWWEIIPLLPAMRQGRHIHWPSVRAIQGKEFEVYTRKPRPINTDGEITTYTPAVFRVIPMAISVLVPPL
>NC_019771.1|WP_015212316.1|48318_48909_-|exopolysaccharide-biosynthesis-protein
MHSRFSQQIKSLLQGLAEQSLTIGDILAETSERGFSLVISLLVLPFLLPMPPGFTGPFGGTCLLLSAQMVLGRRTPWLPRKIANYQFPHAIAQIILQNLHRVTRVLEKITRPRLMQIASHPWIWRLNGLCIFWLTILLILPIPFTNPIPTVGILLLAVAMIESDGLLICISYVITALITLLFGFVGYALWFATLKN
>NC_019771.1|WP_015212315.1|46845_47709_+|metal-ABC-transporter-permease
MIQTLIEPLQYGFMQRSLIIAILVGLLCAVVGSYLMVQRLALLGDAISHSVLPGLAIAFMIGANIFVGAFIAGIVSTMVIAFIKTRSPIKEDAAMGIVFSAFFALGVTLITVIQKDNKIDLNHFLFGNILSVTVDEVRDTTIIAAIVLIVIVLLYKELLFYTFDPLGAQAAGLPVNRLNFGLMLLIALTIVASMKAVGVILVLSLLITPGATAYLIVKRLHEVMIVGAIIGVISSISGMYISYFYNLPSGPAIVLVVSSLFTLALLFSPRHGIIFASRQPRKQALEK
>NC_019771.1|WP_015212314.1|45804_46632_+|metal-ABC-transporter-ATP-binding-protein
MQNVSFYQKISSLQRQVRAISEQTIKPIVMNPTAAINISHLGVHYRTQEALRDINCIIKPGRLTGIFGPNGAGKSTLMKAILGLVPLNNGQVLYEGKALMQQLERVAYVPQRSQIDWNYPATVWDVVMMGRVKKTGWLRSFSTVSRQVAKDALERVGMETFKNRTIGELSGGQQQRVFLARALTQQAEIFCFDEPFVGIDQKTQTIIFEVFQELAAANKIVLVVNHDLGESIVHFDDLILLNCELIATGSRQQVLTEQNLHQAYGGKVMYFSDAA
>NC_019771.1|WP_015212313.1|44710_45679_-|metal-ABC-transporter-substrate-binding-protein
MKKTKIFRLCVVILLPLTLLSCTQSDSLPRRNGKPQVVATSTVIADLAEEVGGEEIDLLGILQAGADPHVYEPVPADSRVLEAADLILYNGYNLEPGIIKLMNASGGKARKLAVGEVVKPLKLEKSKGQIVPDPHVWGSGENAILMVKAIRDGLIELSPEDKDKFTQKAAQLTDELQQLNIWIRQQIQTIPLEKRKLITTHDAFQYYGNTYGIEIAGTLIGISTEEQPSAQTVKQLVDSVKKIGVPAIFAETTINPALIKTVAQEAGIKLAPQQLYSDSIGAKGSDGDTYIKMMVANTRAIVTALGGKYTPFELKPKIEAKS
>NC_019771.1|WP_015212310.1|42842_44300_+|S8-family-serine-peptidase
MTLDITHNFSSKKELNITPISSVNTFDNQADNSLSWGNRSSSLQQETKESVVTTSSYNSRNGYGLINAGKAVSEAAGESPYADAPDLGGNNWGADLVNAPAAWERGHTGQGIIVAVLDTGVDYNHTDLNDNIWTNSKEISGNGIDDDGNGYIDDIQGWNFDSNNNNVLDNNGHGTHVSGTIAGENNDTGVTGIAYNSKIMAVKVLDENGSGSYSNIAKGIYYAVDNGANVINLSLGGNSGNDTLKSALEYASSKGVIVVMAAGNNSESTPSYPARYADNLGIAVGAVDKNKNLTDFSNRSGSQEIKYVTAPGQDIYSTVPNNQYATYSGTSMAAPHVAGVVALMLSANPNLTDSQIRDIITRTAENGTQTPEPTQPSNPTPSLPFPFPIELPFSLINIGSLFPFDNIGSLFPLEAQSTISLEPIVLSVGDMSTATPKVEEFSYHNQSHDRWELSYYDSDLTNYTITEDADLSGVRSQEEEYFTSY
>NC_019771.1|WP_015212322.1|59836_60301_+|hypothetical-protein
MNKLLDESLSLQVAESIKSKAKKPFENAYKAALATEGSRYVQGFLVFTGQPYKPVEHGWIELDEVIIDPTLPYLQKNHKNLWYFPAQSLTLKKLKAIIDESKEDYPEDDPLPVYGQSPYEYYGDLMLGDQEYLTAYQAAEVKCREINGLNAEGN
>NC_019771.1|WP_015212323.1|60429_60828_-|nuclear-transport-factor-2-family-protein
MTTTSENTLKVAQQAFEHFTNGLETGNWQAFLDILTDDFSFWFPMGKFHGLNVGKERAKEFFDYVSEAFKPGLKLKSLDNITSNEKTVIFEFRDEGKLLGEPYKNRVAVAFDVRENKICGYREYFGSDGKSY
>NC_019771.1|WP_015212319.1|61066_62287_+|ISL3-family-transposase
MKFSVDQILNLPEMKVLDFQELVGAGIIITIEKAVNYSTCPDCEKTTYSIHQNHWRLIHDLSWSEKPVLLRINRRQFKCNKCKKVFSEKLNFVDKSKGYTKRLAIDIVAQVLDSNIHSVAERNDLSDEEVESMLKAQVSQILNINLNQVKRLGIDEIALVKGQGSYLAVLVDLDTRKPIELVKSRRIEEIREVIVKWGSQVLEQIVEVSMDLWSPYKSLVEELMPNANITADRFHVMKQVNDELDAMRKSEKRAAMSLDNKSERDRILAGLNKSKYSLIKNEDSLNEQQKERLNNVQKVSPILAKMHALKEEFRDIFESTKSWGESIMNLLDWMHDGLSYFPKSIGTMIRWFGEVVGYFDGRTTSGTVEGINNKLKLIKRLGYGFRNFSNFRLRSLLNWHFSINSP
>NC_019771.1|WP_015212324.1|62370_62940_+|nicotinamide-mononucleotide-transporter
MTYIEIIAAIFGLVSVWLTVKENIWCWPTGLVMVFLYIFVFYEARLYSDAILQVIYIFLQIYGWYAWLHGGNDDSPLAVTRISNQGKLIWSGVAVVGTFGLGYIMHNYTDAALPYPDASITILSLIAQWLMAKKILECWIIWIMVDLIAVGVYAVKHLYPTTGLYTVFLVLAVLGYKEWKRAYKKLRLG
>NC_019771.1|WP_150111057.1|62936_63893_+|AAA-family-ATPase
MILGKFMPPHLGHKYLVDFARNYVDDLTVLVCSIQSEPIPGDLRYCWMKQIFSDVNVVHVTDENPQEPKDDPNFWQIWYDSIRRVLPTGPDYVFASEDYGWKLAEILGASYIPVDHGRNLVPVSGTQIRQNSLTNWRYLPESVRPYFVRRVCIFGAESTGKSTLTQNLANHYHTVYVSEYARGLLDFKGGHCDFTDIPLIARGQMASEDALVHQANKVIFCDTDLITTTIWSDVLFGKCPRWIEEEGNRRQYDLYLLLDVDVPWVNDSQRFLVNYREEFRDRCIQALESRNRPYIIINGDWKQRWQKACRAVDELLER
>NC_019771.1|WP_150111058.1|64378_65365_+|DUF4437-domain-containing-protein
MTIQPANKNSFFYHNNVNLLHTNTGIQMNNKASTGRKHVETEESLNSVINFPQLPFEVKNFITGEFGTAQILSINKSTGESTERVVLNKGWDAPIGHFTTDVEIFVLTGVLCQGGFKLRNLSHSFIPAGIPTGPWKTEEDTIILWMPDATPTYITEDYTSLEQTRENSVYHPNMQTHERMTEYIPLQELHAMKWESTTFLPPGSARKSLYTNKKTGRATWILGLVPMWLEGNFYAGHPTTEEAYVISGDILGHWSMSDDPFNRRYSAMCKDGYYWRPAHIPHGPFWTESGALLLFRTLDQLNCYWILHNPDITQQDQALLQAALEKNK
>NC_019771.1|WP_015212327.1|65958_66387_+|GFA-family-protein
MSNVSVAKGSCLCGVVSVSTTNMSNHVGACHCNMCRQWGGGPLLAIECGSDVTFSGEENIGVYQSSEWAERGFCKRCGTHLFYKLRQNNQFFMPVGLFNNGEGLIFDHQFFIDEKPEYYCFANATNNLTGAEVFAQFAPPSE
>NC_019771.1|WP_015212328.1|66502_67891_-|histidine--tRNA-ligase
MAKSDKINFSTPSGFPEFLPSEKRLEVYLLDIIRRVFESYGFTPIETPAVERLEVLQAKGNQGDNIIYGIEPILPPNRQAEKDKSGETGSEARALKFDQTVPFAAYIARHLNELTFPFARYQMDMVFRGERAKDGRFRQFRQCDIDVVARGKLSLLYDAQMPAIITEIFEAINIGDFVIRINNRKILTGFFQSVGVAENQIKACIGIIDNLEKIGETKVKLELEKEGISLEQTEKIIEFIKIDGSVDDVLDKLKHLAQHFPEAEQFNLGVSELETVINGVRDLGVADKRFCIDLSIARGLNYYTGTVYETTLIGHEALGSICSGGRYEELVGMFLGEKMPGVGISIGLTRLISRLLKAGILNTLSATPTQVVVVNMQEDLMPVYLKVSQQLRQAGINVVTNFEKRPLGKQFQAADKQGIQFCVIIGADEAAAQKSSLKDLKSGEQVEVALADLAEEVKRRLV
>NC_019771.1|WP_015212329.1|67930_68377_-|DUF3598-family-protein
MSNIRLEMPVLARHEGEWVGTYTLVDTTGKILDSHQSHLSCQFPANSDYSYYQINRYTWENGKQEEHKFPGTYQDKKLWFDTERIQGKAWEVDDATVILWFGYKQFPDMYLYEMIQISPDNNYRARTWQWFKNDQIYQRTLIQEERLK
>NC_019771.1|WP_015212330.1|68472_69894_-|aldehyde-dehydrogenase-family-protein
MTKPIEVRNPRTGKFDYVIIPPPPKLLSQQCHRLRRGQIYWQKLGIEGRIDALKQWKQAILSERKQLTDALVSDTGRLSTTVLEIDSFLSSIDRWCNLAPQLLQETSKNTAIPFIALQQTAVPYPLVAVISPWNFPLLLSTIDTIPALLAGCAVIVKPSEITPRFVAPLMTALNTVPKLRDVLNFVEGAGQTGAALIEEVDLVCFTGSVETGRIVAQTAARNFIPSFLELGGKDPAIVLESANLDLATSAILWGSVINSGQSCLSIERIYVAESIFEEFYHQLVTKASHLQLAYPTVESGEIGPIISENQAAIINEHLQDALLQGAVIHCGGKVEELGGGWWCRPTVITEVDHSMKVMTEETFGPIMPVMAFSTVEEAVDLANDSIYGLSAAVFAQSEELAIEVAQKIDVGAISINDAGLTSMMHEGEKNAFKFSGLGGSRMGAAALKRFMRKKAFLIKTNTNKDPWWFNEGE

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Crispr_ID: NC_019771_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_2

94798-94919

Orphan

A:N

Consensus_repeat	Method
TGTCAGAATCAGGATATCCAGGATTTCAGGATTTACAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019771_2

>merge|NC_019771|2|94798-94919|CRISPRCasFinder
TGTCAGAATCAGGATATCCAGGATTTCAGGATTTACAGCATGATAGTGTTTAATGGTTAGTGGTGATTTTCTGATTTAAGTATTTGTCAGAATCAGGATGTCCAGGATTTCAGGATTTACAG

>NC_019771|2|2|94798-94919|CRISPRCasFinder
TGTCAGAATCAGGATATCCAGGATTTCAGGATTTACAG	CATGATAGTGTTTAATGGTTAGTGGTGATTTTCTGATTTAAGTATT
TGTCAGAATCAGGATGTCCAGGATTTCAGGATTTACAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015212352.1\|93209_93476_-\|type-II-toxin-antitoxin-system-ParD-family-antitoxin	unknown	unknown	gnl\|CDD\|274227
NC_019771.1\|WP_015212348.1\|88772_89717_+\|cytochrome-c-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224537
NC_019771.1\|WP_015212343.1\|84311_84674_+\|four-helix-bundle-copper-binding-protein	unknown	unknown	gnl\|CDD\|153434
NC_019771.1\|WP_015212355.1\|95975_96587_+\|cupin-region	unknown	unknown	gnl\|CDD\|227840
NC_019771.1\|WP_015212357.1\|97440_101031_+\|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|227922
NC_019771.1\|WP_015212349.1\|89759_91406_+\|cytochrome-c-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|213748
NC_019771.1\|WP_015212347.1\|88025_88319_+\|ferredoxin-III,-nif-specific	unknown	unknown	gnl\|CDD\|274356
NC_019771.1\|WP_015212353.1\|95159_95651_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015212351.1\|92291_92858_-\|Uma2-family-endonuclease	unknown	unknown	gnl\|CDD\|368559
NC_019771.1\|WP_015212364.1\|105754_107029_-\|dicarboxylate/amino-acid:cation-symporter	unknown	unknown	gnl\|CDD\|366058
NC_019771.1\|WP_015212359.1\|101318_101762_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|238038
NC_019771.1\|WP_015212344.1\|84796_85246_+\|DUF29-domain-containing-protein	unknown	unknown	gnl\|CDD\|366774
NC_019771.1\|WP_015212342.1\|83176_83776_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373150
NC_019771.1\|WP_015212358.1\|101056_101317_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_042464384.1\|85429_87019_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NC_019771.1\|WP_015212361.1\|103289_104168_-\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224995
NC_019771.1\|WP_015212350.1\|91540_92137_+\|heme-copper-oxidase-subunit-III	unknown	unknown	gnl\|CDD\|224758
NC_019771.1\|WP_015212356.1\|96768_97260_+\|nitrogenase-associated-protein	unknown	unknown	gnl\|CDD\|239331
NC_019771.1\|WP_015212360.1\|102682_103207_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|239942
NC_019771.1\|WP_015212363.1\|104543_105722_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|224481

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015212352.1\|93209_93476_-\|type-II-toxin-antitoxin-system-ParD-family-antitoxin	gnl\|CDD\|274227	TIGR02606, Antitoxin_ParD, putative addiction module antidote protein, CC2985 family. This bacterial protein family has a very similar seed alignment to that of pfam03693 but is a more stringent model with higher cutoff scores. Proteins that score above the trusted cutoff to this model almost invariably are found adjacent to a ParE family protein (pfam05016), where ParE is the killing partner of an addiction module for plasmid stabilization. Members of this family, therefore, are putative addiction module antidote proteins. Some are encoded on plasmids or in prophage regions, but others appear chromosomal. A genome may contain several identical copies, such as the four in Magnetococcus sp. MC-1. This family is named for one member, CC2985 of Caulobacter crescentus CB15. [Cellular processes, Other, Mobile and extrachromosomal element functions, Plasmid functions].	9.59637e-06
NC_019771.1\|WP_015212348.1\|88772_89717_+\|cytochrome-c-oxidase-subunit-II	gnl\|CDD\|224537	COG1622, CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion].	3.84435e-69
NC_019771.1\|WP_015212343.1\|84311_84674_+\|four-helix-bundle-copper-binding-protein	gnl\|CDD\|153434	cd08026, DUF326, Cysteine-rich 4 helical bundle widely conserved in bacteria. This functionally uncharacterized protein forms a 4-helical bundle with a bromodomain-like topology. It is present in major bacterial lineages and contains highly conserved cysteines in a repeated pattern, whose sidechains appear buried. Some family members have been (mis)annotated as putative ferredoxins.	6.91723e-22
NC_019771.1\|WP_015212355.1\|95975_96587_+\|cupin-region	gnl\|CDD\|227840	COG5553, COG5553, Predicted metal-dependent enzyme of the double-stranded beta helix superfamily [General function prediction only].	8.83913e-66
NC_019771.1\|WP_015212357.1\|97440_101031_+\|HEAT-repeat-domain-containing-protein	gnl\|CDD\|227922	COG5635, COG5635, Predicted NTPase (NACHT family) [Signal transduction mechanisms].	2.57285e-68
NC_019771.1\|WP_015212349.1\|89759_91406_+\|cytochrome-c-oxidase-subunit-I	gnl\|CDD\|213748	TIGR02891, Probable_cytochrome_c_oxidase_subunit_1-beta, cytochrome c oxidase, subunit I. This large family represents subunit I's (CtaD, CoxA, CaaA) of cytochrome c oxidases of bacterial origin. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits I-III form the functional core of the enzyme complex. Subunit I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit II and heme a of subunit I to the bimetallic center formed by heme a3 and copper B. This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer. In the bacilli an apparent split (paralogism) has created a sister clade (TIGR02882) encoding subunits (QoxA) of the aa3-type quinone oxidase complex which reacts directly with quinones, bypassing the interaction with soluble cytochrome c. This model attempts to exclude these sequences, placing them between the trusted and noise cutoffs. These families, as well as archaeal and eukaryotic cytochrome c subunit I's are included within the superfamily model, pfam00115. [Energy metabolism, Electron transport].	0
NC_019771.1\|WP_015212347.1\|88025_88319_+\|ferredoxin-III,-nif-specific	gnl\|CDD\|274356	TIGR02936, fdxN_nitrog, ferredoxin III, nif-specific. Members of this family are homodimeric ferredoxins from nitrogen fixation regions of many nitrogen-fixing bacteria. As characterized in Rhodobacter capsulatus, these proteins are homodimeric, with two 4Fe-4S clusters bound per monomer. Although nif-specific, this protein family is not usiveral, as other nitrogenase systems may substitute flavodoxins, or different types of ferredoxin. [Central intermediary metabolism, Nitrogen fixation].	1.26837e-43
NC_019771.1\|WP_015212360.1\|102682_103207_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|239942	cd04496, SSB_OBF, SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.	5.01961e-22
NC_019771.1\|WP_015212351.1\|92291_92858_-\|Uma2-family-endonuclease	gnl\|CDD\|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	9.23975e-27
NC_019771.1\|WP_015212364.1\|105754_107029_-\|dicarboxylate/amino-acid:cation-symporter	gnl\|CDD\|366058	pfam00375, SDF, Sodium:dicarboxylate symporter family.	6.83748e-90
NC_019771.1\|WP_015212359.1\|101318_101762_+\|HNH-endonuclease	gnl\|CDD\|238038	cd00085, HNHc, HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and anaredoxins.	2.38587e-08
NC_019771.1\|WP_015212344.1\|84796_85246_+\|DUF29-domain-containing-protein	gnl\|CDD\|366774	pfam01724, DUF29, Domain of unknown function DUF29. This family consists of various hypothetical proteins from cyanobacteria, none of which are functionally described. The aligned region is approximately 120-140 amino acids long corresponding to almost the entire length of the proteins in the family. Structure 3fcn is a small protein that has a novel all-alpha fold. The N-terminal helical hairpin is likely to function as a dimerization module. This protein is a member of PFam family PF01724. The function of this protein is unknown. One protein sequence contains a fusion of this protein and a DnaB domain, suggesting a possible role in DNA helicase activity (hypothetical). Dali hits have low Z and high rmsd, suggesting probably only topological similarities (not functional relevance) (details derived from TOPSAN). The family has several highly conserved sequence motifs, including YD/ExD, DxxNVxEEIE, and CPY/F/W, as well as conserved tryptophans.	1.08362e-51
NC_019771.1\|WP_015212342.1\|83176_83776_-\|hypothetical-protein	gnl\|CDD\|373150	pfam14597, Lactamase_B_5, Metallo-beta-lactamase superfamily. This is a small family of putative metal-dependent hydrolases.	1.05731e-136
NC_019771.1\|WP_042464384.1\|85429_87019_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.65895e-09
NC_019771.1\|WP_015212361.1\|103289_104168_-\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	4.25081e-79
NC_019771.1\|WP_015212350.1\|91540_92137_+\|heme-copper-oxidase-subunit-III	gnl\|CDD\|224758	COG1845, CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 [Energy production and conversion].	4.00064e-62
NC_019771.1\|WP_015212356.1\|96768_97260_+\|nitrogenase-associated-protein	gnl\|CDD\|239331	cd03033, ArsC_15kD, Arsenate Reductase (ArsC) family, 15kD protein subfamily; composed of proteins of unknown function with similarity to thioredoxin-fold arsenic reductases, ArsC. It is encoded by an ORF present in a gene cluster associated with nitrogen fixation that also encodes dinitrogenase reductase ADP-ribosyltransferase (DRAT) and dinitrogenase reductase activating glycohydrolase (DRAG). ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via glutaredoxin, through a single catalytic cysteine.	3.55032e-72
NC_019771.1\|WP_015212363.1\|104543_105722_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|224481	COG1565, COG1565, Uncharacterized conserved protein [Function unknown].	4.95686e-138

>NC_019771.1|WP_015212352.1|93209_93476_-|type-II-toxin-antitoxin-system-ParD-family-antitoxin
MNITLKPEQEQFIQNQLAQGRFPNAEAVVNQALQLLQEKQREYEEWVEDVRVKVNEAGEELERGEGVPLATVVEQIQAKFRNAREANK
>NC_019771.1|WP_015212351.1|92291_92858_-|Uma2-family-endonuclease
MVQTKHRFASFEEYLSYDDGTDNLYELFNGELVEMPPESGINVQIANRLFLIFALLIGIDRVRGHGLELEVRGEPRNRYPDLTIIREEHIQQLASRNTIRLSMSPPLLVVEVVSPGELQRDRDFIAKRLQYQDCGIPEYWIIDPQTKSILILELINEVYDEIGIFSGDNLVRSPQFNSLNLQASQIFD
>NC_019771.1|WP_015212350.1|91540_92137_+|heme-copper-oxidase-subunit-III
MTAITTSEHHEAGHEEHQDLRVWGLLTFLVSESLMFGGFFATYLFFRGTTAVWPPEGTEVELFIPTINTIILVSSSFVIHFGDMAIKRNSVGWMRFWYFITAIMGAVFLAGQVYEYMNLGYGLTTNIFANCFYLMTGFHGLHVFIGLLLILGVLWRSLRRGHYSDTKHTGIEMAEIYWHFVDIIWIVLFTLVYILNAF
>NC_019771.1|WP_015212349.1|89759_91406_+|cytochrome-c-oxidase-subunit-I
MTQVEFPPNTPHTSHPTAWKWRDYFTFNIDHKVIGIQYLVTAFGFYIIGGLMAIALRTELATADSDFLDPNLYNAFMTNHGTIMIFLWIVPSAIGGFGNYLVPLMVGARDMAFPKLNAIAFWLNPPAGLLLLLSFIFGGSQSGWTAYPPLSLVTAPIAQTMWILAIVLVGTSSILGSLNFVITILLMKVPSMKWDQVPLFCWAILATSVLALVSTPVLAAGLILLLFDINFGTSFFKPDAGGNVVIYQHLFWFYSHPAVYLMILPIFGIMSEVIPTHARKPIFGYKAIAFSTVAICVVGLFVWVHHMFTSGTPGWMRMFFTISTLIVAVPTGVKIFGWVATLWGGKIRFTSAMLFAIGLLSMFVMGGLSGVTMGTAPFDVHVHDTYYVVAHFHYVLFGGSVFGIYAGIYHWFPKMTGRMMNETWGRVHFVLTLIGTNLTFLPMHKLGLQGMPRRVAMYDPQFVSLNQLCTIGAFILGISVIPFAYNAITSWKKGELAGDNPWESLTLEWTTSSPPIIENWEVLPVVTHGPYDYGHIHDESSSVTEAVS
>NC_019771.1|WP_015212348.1|88772_89717_+|cytochrome-c-oxidase-subunit-II
MQKVPVSLWTLLAGMIISPISIWIGQNHHLLPVQASQQAPLVDGFFNIMFTIAVALFLVVEGTILIFLFMYRRRPGDNGDGTPVEGNLALEIFWTAVPTVIVIVLGIYSVDIYNKMGGLEPGSHPHGQMAMAATMNDGSEAVTAGIGIGGSPQTQGKAADLVVDVKGIQFAWLFNYPQTGIAAGELHVPVGADVQLNLSADDVIHSFWVPQFRLKQDALPGIATELRFVATKPGTYPIVCAELCGGYHGSMRSQVVVHTQEDFDSWLTENQIAQQQGQPQVVAVNPANLSTPDFLAPYVSEMGVNAATLTQIKK
>NC_019771.1|WP_015212347.1|88025_88319_+|ferredoxin-III,-nif-specific
MATLTGVTFGGKTWTPKFAQEIDKDKCIGCGRCIKVCGHNVLGLKALNEEGEFVEDEDDEEIERKVMAVVTPENCIGCEACSRICPKNCYSHTTVDN
>NC_019771.1|WP_042464384.1|85429_87019_-|helix-turn-helix-domain-containing-protein
MPYTIPNKNCVRCDKCRPQCPTGAIKIENNEYWIDPCLCNNCEGYYPEPQCVIACPINAPIPAQAKKGRCKIEPREPTSPDLFSNGKNHPFASAIVIWEACNLLAQRKSLTWETDAEDNLHYSRQVNQGRGAISFHIQDPFQITNLAKDLHVIESLDIRATCIHLIFAAHATALDKPWEQEFAIDERQIEKYLGLEKRKDLNKTAKLSLIKNIVQQACSLIVTIDWPQRGRVPGFSVTQSHLWHLTDVQHHFQEDDLGCKYLIGLTFKVKTGTWSQHFLNRQASKERSGFYQYGSLPKTLLTTVMSLWQQHEGAIRLMLWLLFKTKMGREQRITVPTLMRVAYGEEKINLASRLRDERKRLLRTFENDLEVLNHYGVKPLFDPITYPPEIQPLWAKLIDIPEDPDEALEFWINDGSGDNRLTDSGPRGKWNLLMNARILSFELPSEWEQLSSEAEKKKRSTVKSKKTLKSTDDLLGEQVLQARKNINISQRELARLTGKSQSWIRDVENGRLKPKLEDQALLRKVLNIS
>NC_019771.1|WP_015212344.1|84796_85246_+|DUF29-domain-containing-protein
MSKKSIKNLYEQDFSLWVEDTVSKLKARDNENLDWDNLIEEVESLGKSQRKAVRSFLVRLIEHLLKRCYVPMSDCYRGWEIEIRNFRQRLQIELEDSPSLKSFVLEILAKSYDMALENVRDGYPDVYFSDVCPFPSNVDALLSKKFWEE
>NC_019771.1|WP_015212343.1|84311_84674_+|four-helix-bundle-copper-binding-protein
MLMMMTENITSEIQTCMNSCMECHKICLETMAYCMSKGGKYMDMGMISIMRDCSEMCMMCMNMMMGGSEFMGRTCMLCAEMCDRCAAACEKISDDRKMMECAAVCRRCAETCRSMQMMPA
>NC_019771.1|WP_015212342.1|83176_83776_-|hypothetical-protein
MKSLHRNDLYSWSCFNPARNIDFNGFAWIRPEGNILIDPVALSNHDWNHLESLGGVAWIVLTNSDHLRSAKDIANQTYAKIAAPKGEKEDFSILCNRWLTDGEELVPGLKVIEIQGSKTPGELALLLEETTLITGDLVRSHKAGTLTILPDEKLLNRDQAVASVRRLAGLEKVEAVLVGDGWSVFRNGRERLQELLGTL
>NC_019771.1|WP_015212353.1|95159_95651_+|hypothetical-protein
MLESSQNKYSWFDVAEDVKELLILAAQTWENTEESTKYMQQALAKTGDNTDVLVAAYRYFYYKNNYVLALTTAEKITAKIKEVEKFPDNWEQLQPILVKRHEEHQIRLYLNAYAASGLVLAKLGELEQAREISARVKSIDDKNDFGSSILLDILTRLPEDDDD
>NC_019771.1|WP_015212355.1|95975_96587_+|cupin-region
MQGKDWFVAGDGQHQACKSARTWDLLRDNYRLYRFLTEVEDVLNNVEDESTCLPEIRMLVRRLIVNSYWVQSQFLAPDSKTGTSVLLLYDELGFPLTVQTVTFAPGTISNIHNHGTWGVVAVLKGEEKNTFWRRSSNPEFPDKIETTGEINLFPGDIISFAPDTIHQVQAVGEQPTVTFNIYGETNPKERFEFDTIHHIAKKF
>NC_019771.1|WP_015212356.1|96768_97260_+|nitrogenase-associated-protein
MARVIFYEKPGCKGGTKQKVLLTAAGHEVVTYSLLTEPWTAERLRSFFGDRTVSEWFNKSAPKVKSGEVIPESIDADTALVMMLRDPLLIRRPLIEVGNRREVGFDVEKIDAWIGLKPVDDSLKEMSEKLMQQNLQGCSHGHDHEHHHGKGGCKNHGQEQHQH
>NC_019771.1|WP_015212357.1|97440_101031_+|HEAT-repeat-domain-containing-protein
MLDWLLIWGVTQGVGVLVTPILQDLAKEGAKDFAKDFFKDSLKHVLLREKDPRQVAAGKAIKEFLQLVQQQLKIRCKLPENEIKPYIQEVKRFISDKSVKSILGKAFEIDCDSLDATTLKNTWNSLQLKPLPNNFNWDAIINQYLMNVQEILFDSKDLRDLLDSQNIEKIEKSTQEIAGIIPDFDLLGYQEAIKETYGNLKLESLDTTGYAYNELKLWRMFIAQNVREVHQVLPQIYELPKEHLNRLRESNQLEAEVAIQELERYKQSYFEQATRPVLDIINDKQNYKYVVILGDPGSGKSTLLQFLALNWAESPIDNVISQPIPLLIELRTYMRRREDNECHDFIEFFHKCSGSIYHLNQHKLHEQLLAGNALVMFDGLDEVFDPGKREDVITDIHRFTNKYPQVRVIVTSRVIGYKTQRLRDTEFHHFMLQDLDAEQIQDFINRWHELNFNNEADKLRKKERLQGAVANSKSIKELAGNPLLLTMMAILNRNQELPKDRPELYHQASRLLLHQWDVERALIEDIRLDPKTIDYKDKQAMLRQVAYSMQANQKGLTGNLITASDLETILTDYLKTIVDKPREAARVMINQLRTRNFILCFVGADYYAFVHRTFLEYFCAWEFVWQFEKERSISIEQLKTDVFAKHWQDESWNEVLRLIAGMLEPKFTGEIIDYIMTTNILHYVEEEQGINFFLEAGVDRRIINYLINKNEKEEQFINIFLAAELLGEVRNYHIIKSTAHKLLEMLKYLTQYDISYYYETYDKEAKFVDRVRSNAVTQIATLWQDDPNTLSWLKQSATVGNNSDMRIAAVQELIQKFKDDLDTVSILKQLATSDDDGNVRRAAMRKLAQDFQEDPDTLPILKKLAISDVNLNVRRAAMRELARNFKDNPETLLFLKQLITSDKSFLTRRTAVEELARNFKDDPETLLFLKQLITSDNGNVRCTVVQALAKHFKDDTSTLPILKKLANCDDDANVQGEVVDALAWNFKDDPDTLQIIKQLATSEDRNVRFQAAQTLANYFQDDPNTLPFLKEMATLDDDANVRSVVLARLVDNFKDDPDILPIFKQLATSDDHWNVRCAAAQGLADNFKEDPDTLTILKQFATSDDDETVRYTAIRGLAKYFKTNPDLFELFYKCAMNDTFERKEEWGKNPRLLALKIIIKPYPNHPQTLRLLHDRAENDPDEQVREFAKQELAKLN
>NC_019771.1|WP_015212358.1|101056_101317_+|hypothetical-protein
MNTSVKTIKVYDEIVDFIAAGTTPQSVINFHLSETAQNRLEDLIDGAKNNQLTKEEKRELDHFLTLEHIMTLAKAKAYKYMNTEDK
>NC_019771.1|WP_015212359.1|101318_101762_+|HNH-endonuclease
MSRTYINVDLRRLVVERAGNICEYCLISAVDRSSGCQVDHIISVKHGGASTDDNLCYACVFCNLQKGTDLGSINWRNGELVRFFNPRRDLWGDHFRLDEAVIQPLTDIGEVTTRILDFNNDERIIERLLLIEVGKYPPTSAKGRISK
>NC_019771.1|WP_015212360.1|102682_103207_+|single-stranded-DNA-binding-protein
MNSCILMAEIYDTPQLRHTPDGLEVTEMIVHVPGVRPDDPSHPLKVVGWGNLAKEIHQTYKEGDRVIIEGRLGMNTFDRPEGFKEKRAELTVQKIHGIGKEMNSSPPATTMAQPAQRPPESYESTRPAPTPVTTNVAVTPQVTTPEPTYQPANFQPPSYQPVSAPEPDPDDIPF
>NC_019771.1|WP_015212361.1|103289_104168_-|NAD(P)-dependent-oxidoreductase
MKVAFLGTGLMGLPMAQRLLAANVELIAYNRTPEKLAPLQAAGAEIATKPRQAIRSADCIVLMLSNAAAIYHVLLTDTSWHTLSGRSVIQMGTLTPPESQEIRDAVVAAGGEYIEAPVLGSIPEAETGKLIVMVGGEQEQYQRHLKLLQIFGTDPVYIGPVGSASSLTLALNQLIASLTTSFALSLAFVQMQGIDVDLFMRILRDSKLYAPTFDQNLKRMLDGNYTKANLPTKQLIKEIDLFITEAKSLGLNLSSIEGVRQILQSAMSMSYPEDDYSSVFPAIREWGEASGE
>NC_019771.1|WP_015212363.1|104543_105722_-|class-I-SAM-dependent-methyltransferase
MDSHPALCAAIAKRIKTSPQRRITFAEYMDMALYHPEHGYYASDAVNIGFRDGDFFTSSSLGSDFGELLAVQFCQMWEILGQPMPFHLVEMGAGKGVLASHILNYIQLNYPDLFAALKYIIVEKSPSLRQEQQQRLQEFSVQWFNLEEIAANSITGCFFSNELVDAFPVHQFTIEAGELQEIYVTVEDDGENTPVFPRFMEVLGELSTPQLAAYFDLVGIELNPNIYADGYRSEINLAALDWLSIVADCLQRGYVLTIDYGYPANRYYNPRRSQGTLQCYYHHRHHDNPYVNVGRQDITAHVDFTALESWGNRCGLNQVGWTQQGLFLMALGLGERIAALSYQQQPISQMLNRREALHQLIEPTGMGNFGVLVQSKGLTETLPLLQGLTIPE
>NC_019771.1|WP_015212364.1|105754_107029_-|dicarboxylate/amino-acid:cation-symporter
MGQMVQKKHLFAWKRIPLALQIALAIILAILVGNLLSTQAVTNTALISNLAIPCNLILKALRALATPLIMLAVLHAFLTADIPGRSGRRLTVLLLTNTTVAIFIGLLVANLLKPGSWGRISPPSGTEATGKTLDPWGLVQDIIPDSILKPLVDNNVIQLIFISLAFGIVLRALKAQQIEEGKTYYQAIEGVITILFEAVIRILHWIIALVPLAVFGIVAKTVALQGFAPFKSLGAFIIAVLLALSLQACYYLLRVKFGSWVTPKNFLAGGSEALLTAFSTASSTATTPITFEALLHKIGLRESSASLGALVGSNFNNDGTALYEAMSALFIAQVLGLHLSLPQQLIVVVTAIFASVGAAGIPEAGLVTMTLVFTSVGLPTEYIALLVTVDWFLDRCRTAINVMGDMTVSCLLDGKKRLIMNIDS

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Crispr_ID: NC_019771_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_3

303518-303681

Orphan

A:N

Consensus_repeat	Method
AAAAATAATCAAAATTAATCCTGTACATCCTAAAATCCTGTAAATCCTGATTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019771_3

>merge|NC_019771|3|303518-303681|CRISPRCasFinder
AAAAATAATCAAAATTAATCCTGTACATCCTAAAATCCTGTAAATCCTGATTCAAGATTTATCACAAGCCGTAGACCAAGCAAGGATTAATAAGATTAAACAAATACATGAAAAATAATCAAGATTAATCCTGTACATCCTAAAATCCTGTAAATCCTGATTCA

>NC_019771|3|3|303518-303681|CRISPRCasFinder
AAAAATAATCAAAATTAATCCTGTACATCCTAAAATCCTGTAAATCCTGATTCA	AGATTTATCACAAGCCGTAGACCAAGCAAGGATTAATAAGATTAAACAAATACATG
AAAAATAATCAAGATTAATCCTGTACATCCTAAAATCCTGTAAATCCTGATTCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015212521.1\|315032_315383_-\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|234669
NC_019771.1\|WP_042464419.1\|291603_293331_+\|DNA-repair-protein-RecN	unknown	unknown	gnl\|CDD\|223571
NC_019771.1\|WP_015212513.1\|305570_307946_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|223769
NC_019771.1\|WP_015212514.1\|308342_309242_+\|heterocyst-differentiation-master-regulator-HetR	unknown	unknown	gnl\|CDD\|183916
NC_019771.1\|WP_015212503.1\|294041_294449_+\|DUF393-domain-containing-protein	unknown	unknown	gnl\|CDD\|225556
NC_019771.1\|WP_015212520.1\|314506_314986_-\|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|319971
NC_019771.1\|WP_015212516.1\|310705_311314_+\|30S-ribosomal-protein-S4	unknown	unknown	gnl\|CDD\|177038
NC_019771.1\|WP_015212517.1\|311389_312376_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NC_019771.1\|WP_015212506.1\|296860_297649_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015212502.1\|293388_294045_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226789
NC_019771.1\|WP_015212505.1\|295948_296833_-\|ATP-adenylyltransferase	unknown	unknown	gnl\|CDD\|226803
NC_019771.1\|WP_015212504.1\|294449_295832_-\|cysteine-desulfurase-like-protein	unknown	unknown	gnl\|CDD\|273906
NC_019771.1\|WP_015212511.1\|302180_303227_+\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|176197
NC_019771.1\|WP_015212509.1\|301097_301550_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|200128
NC_019771.1\|WP_015212512.1\|303688_304942_+\|inorganic-phosphate-transporter	unknown	unknown	gnl\|CDD\|376541
NC_019771.1\|WP_015212515.1\|309550_310165_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015212507.1\|298235_300044_+\|proline--tRNA-ligase	unknown	unknown	gnl\|CDD\|236405
NC_019771.1\|WP_015212508.1\|300135_300843_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|369778
NC_019771.1\|WP_015212519.1\|313717_314401_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NC_019771.1\|WP_015212518.1\|312605_313073_-\|SsrA-binding-protein-SmpB	unknown	unknown	gnl\|CDD\|235455

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015212521.1\|315032_315383_-\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	2.01467e-38
NC_019771.1\|WP_042464419.1\|291603_293331_+\|DNA-repair-protein-RecN	gnl\|CDD\|223571	COG0497, RecN, ATPase involved in DNA repair [DNA replication, recombination, and repair].	0
NC_019771.1\|WP_015212512.1\|303688_304942_+\|inorganic-phosphate-transporter	gnl\|CDD\|376541	pfam01384, PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.	1.1678e-52
NC_019771.1\|WP_015212514.1\|308342_309242_+\|heterocyst-differentiation-master-regulator-HetR	gnl\|CDD\|183916	PRK13245, hetR, heterocyst differentiation control protein; Reviewed.	0
NC_019771.1\|WP_015212503.1\|294041_294449_+\|DUF393-domain-containing-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	7.81758e-33
NC_019771.1\|WP_015212520.1\|314506_314986_-\|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.25539e-61
NC_019771.1\|WP_015212516.1\|310705_311314_+\|30S-ribosomal-protein-S4	gnl\|CDD\|177038	CHL00113, rps4, ribosomal protein S4; Reviewed.	1.91483e-125
NC_019771.1\|WP_015212517.1\|311389_312376_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	2.10212e-134
NC_019771.1\|WP_015212505.1\|295948_296833_-\|ATP-adenylyltransferase	gnl\|CDD\|226803	COG4360, APA2, ATP adenylyltransferase (5',5'''-P-1,P-4-tetraphosphate phosphorylase II) [Nucleotide transport and metabolism].	7.03573e-115
NC_019771.1\|WP_015212502.1\|293388_294045_+\|hypothetical-protein	gnl\|CDD\|226789	COG4339, COG4339, Uncharacterized protein conserved in bacteria [Function unknown].	2.97182e-73
NC_019771.1\|WP_015212504.1\|294449_295832_-\|cysteine-desulfurase-like-protein	gnl\|CDD\|273906	TIGR01976, am_tr_V_VC1184, cysteine desulfurase family protein, VC1184 subfamily. This model describes a subfamily of probable pyridoxal phosphate-dependent enzymes in the aminotransferase class V family (pfam00266). The most closely related characterized proteins are active as cysteine desulfurases, selenocysteine lyases, or both; some are involved in FeS cofactor biosynthesis and are designated NifS. An active site Cys residue present in those sequences, in motifs resembling GHHC or GSAC, is not found in this family. The function of members of this family is unknown, but seems unlike to be as an aminotransferase. [Unknown function, Enzymes of unknown specificity].	1.71984e-157
NC_019771.1\|WP_015212511.1\|302180_303227_+\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|176197	cd08235, iditol_2_DH_like, L-iditol 2-dehydrogenase. Putative L-iditol 2-dehydrogenase based on annotation of some members in this subgroup. L-iditol 2-dehydrogenase catalyzes the NAD+-dependent conversion of L-iditol to L-sorbose in fructose and mannose metabolism. This enzyme is related to sorbitol dehydrogenase, alcohol dehydrogenase, and other medium chain dehydrogenase/reductases. The zinc-dependent alcohol dehydrogenase (ADH-Zn)-like family of proteins is a diverse group of proteins related to the first identified member, class I mammalian ADH. This group is also called the medium chain dehydrogenases/reductase family (MDR) to highlight its broad range of activities and to distinguish from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal GroES-like catalytic domain. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.29131e-162
NC_019771.1\|WP_015212509.1\|301097_301550_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	5.17596e-13
NC_019771.1\|WP_015212513.1\|305570_307946_+\|EamA-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	5.53875e-31
NC_019771.1\|WP_015212507.1\|298235_300044_+\|proline--tRNA-ligase	gnl\|CDD\|236405	PRK09194, PRK09194, prolyl-tRNA synthetase; Provisional.	0
NC_019771.1\|WP_015212508.1\|300135_300843_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|369778	pfam08242, Methyltransf_12, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	6.55866e-14
NC_019771.1\|WP_015212519.1\|313717_314401_+\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	7.2581e-47
NC_019771.1\|WP_015212518.1\|312605_313073_-\|SsrA-binding-protein-SmpB	gnl\|CDD\|235455	PRK05422, smpB, SsrA-binding protein SmpB.	2.68481e-92

>NC_019771.1|WP_015212511.1|302180_303227_+|alcohol-dehydrogenase-catalytic-domain-containing-protein
MKAQVFRGVNQLSYEEIPVPTLEADEVLVQVRVVGLCQSDIKKIRYPLYEPPRIFGHETAGTIASVGANVKGWTVGQRVAVMHHIPCMRCSYCLNDNFSMCDVYKNISTTAGFNASGGGFAEYVKVPGHIVQNGGLIPIPNDISFEEASFVEPTNCCLKAVKKAQIAPGQTVLVTGAGPIGLMFMMLVKYFGARAIATDLLPSRIEKALNVGAEAAFDARDPDLPAKIQALTGGMGVDVTLLAVPSDKAFFQALDCTRKGGKILFFAEFPDELEIPLNPNILYRREIDLMGSYSSSYRLQSLSADIVFNRRIDVKALISDRYPLQDLSQAVDQAIAPTPETYKILIYP
>NC_019771.1|WP_015212509.1|301097_301550_+|helix-turn-helix-domain-containing-protein
MTTFLSNQNKHTVSNIVTENETEAIKQLAELLKQENSQLRLVANGQEVAVSDSVFDVLREIVREMALGNYVSIVTYNPELTTQQAADLLNVSRPYLIKLLEQGELPYIMVGTHRRVRFGDLMKYKENRDIKRDKFLTELTQMSQEAGFYE
>NC_019771.1|WP_015212508.1|300135_300843_+|class-I-SAM-dependent-methyltransferase
MAEQTINFDSNPPVATNEYDTMIQMALPGYEVMHNMTLSVLRASLPEKANLLIVGAGSGMELVKFGKSNSQWQMLGVDPSSNMLSIAQNKIEEYGLSAQIKLFAGYTHDLDPNSFYDAATCILVMHFLPDDGSKLALLQNISQRLKSSGTFILVDIFGEKGTQEFERMIAIIKVYWEQMGITPTKITEGLETIKKGVFPIPEIRVVELLQQAGFCNILRFYTGLWVGGWVATKNS
>NC_019771.1|WP_015212507.1|298235_300044_+|proline--tRNA-ligase
MRLSQMLFVTLRDDPADAEIPSHKLLLRAGYIRRIGSGIYAYLPLMWRVLQKVSQIVREEMNATGAQECLLPQLQPADLWKESGRWDTYTKAEGIMFSLVDRREQQLGLGPTHEEVITTVARDMIRSYRQLPLHLYQLQTKFRDEIRPRFGLMRGREFIMKDGYSFHADEESLKKTYQDMYKAYSNMLRRSGLAFRAVEADSGAIGGSGSTEFMVLADAGEDEVLYTEDGKYAANVEKAVSLPADAETSPFTTYEKRETPGTDTIEKLCNFLKCSPNQIVKNVLYQIVYDNGLTVLVLVNIRGDQEVNEVKLQNELTKLAPQFGGKAIIAFSVPTNETIATWAAKTLPLGYIAPDVADDYITGSKQVNSQFVRLVDQTAVELKNFVTGANEVGFHVVGANWGEQFKLPALTVDIRKAKLGDRSLHDSNQTLQTARGIEAGHIFQLGTKYSQAMGATYTNEQGEEKPLVMGCYGVGVSRLAQSAVEQSYDKDGIIWPVAIAPYHAIVTIPNIKDAQQIAVAEQLYTELNKAGVETLLDDRDERAGVKFKDADLIGIPFRIVTGRAITNGKVEVVKRANRESQEIPIEEVVNTLQQWVKEAIER
>NC_019771.1|WP_015212506.1|296860_297649_-|hypothetical-protein
MQQSTSGNNQDFIRQLATLAAIVGAFVINVLSNIFPLNGINIGEISNTVFKEVLIIPANYAFAIWGLIYLGLFALGVYQFLPNQKNDPDLRKTGYLLVIASVAQSIWVYLFLSKLFALSIIAMLGILIPLIIIYQRLEIGRNRVSKSKKLCLHAPISIYLSWISVATIVNVASALYFYGWNGWGFTNEVWTVIMLLAAAAITTVMVIQYRDIAYAGVTVWAVIAIALKHWDNSLIRYAALVLAIVLIVITIIKNPRLIMGNG
>NC_019771.1|WP_015212505.1|295948_296833_-|ATP-adenylyltransferase
MTQGKILLNPGTLWAKVKQTTAQALQCGALKSIPTEFEFIEQDGVKFLVRILSNLNRKQAAKKKQDQQTANTGKEFNPFLPYEEDLFVADISDTHVCILNKFNVVDYHLLIITRAFEEQESLLTLEDFAAMWACLADFDGLVFYNGGKIAGASQRHKHLQILPFSQPEIPITPLLTAAKFQDSIATIPGLPFLHAFTTLDFGEGAEVTLLKYQTLLAAVGIEAVGNNRQSGAYNFLATREWMLIVPRFQEEFESISVNSLGFAGALLVRNAEQIQLLKDIGIMNVLKKVAWPMK
>NC_019771.1|WP_015212504.1|294449_295832_-|cysteine-desulfurase-like-protein
MESLDLKWIRAQFPALTQTTDGHPAIFFDGPGGTQIPGSVLDAMSDYLVRSNANAHGYFTTSVRTDALIISARAAIADLLGCDHDEVVFGANMTTLTFAVSRAIGRELQPGDEIIVTCLDHAANISPWKALEERGVTIRTVDINIADCTLDINDLESKINSRTKLVAVSYASNAVGTINDIAKIVKLAHAVGALVFVDAVHYAPHASINVHQLDCDFLACSTYKFFAPHVGVLYGKREHLARFTPYKVKPASEEVPSRWETGTLNHEGLAGVVAAINYLAKLGCHVSPTLDNELLSSLMAADKEGLTTFHCPSFLTLSAQPNHELASAYHSRRAALIAAMSAIQQYERELSKKLISGLLEIPGLRVYGITEPSQFIWRTPTVSITIEGQTPANIAKFLGEKGICAWHGHFYAIDLTERLGVEASGGLLRIGLVHYNTVEEIHQLLQVLQEICKNNFFQKP
>NC_019771.1|WP_015212503.1|294041_294449_+|DUF393-domain-containing-protein
MKYTVIYDGQCNLCVTLVQLLETLDQGKLFRYIPMQDEQMLSQWGITAQDCEQGMILIDNNDPLKRWQGSNAAEEIGRLLPLGNLFVEAYRALPGMKWAGDRFYEQIRDHRYTLFGKRGDTYQSAYCVDDSCNIK
>NC_019771.1|WP_015212502.1|293388_294045_+|hypothetical-protein
MLAENITDLLFSHWQQTLQSFNVDPTTANEAFFQLISVYSSPSRHYHTLQHIHYVLNTIETFTTCIQDLPSLQLAAWFHDVVYDTHALDNEEKSADYAANMLKTLAIPATNIIQIHRLILCTKNHQADDLDSQILLDADLAILAATPLQYQEYAQAIRQEYAWVSEAEYITGRGKVLENFLQRQSIYLTPLMLESSEELARFNIKTELQSLQKNRGFI
>NC_019771.1|WP_042464419.1|291603_293331_+|DNA-repair-protein-RecN
MLLCLRIENFALIDHLELEFGAGLNVLTGETGAGKSIILDAIDAVLGGKVSSRVIRTGTSRALVEGTFSINPFLSAWLSEQEIDLIDDNSVIISRDISATSSNIRTRSRINGVLVNRQIMGSLRDRLVEITAQGQTLQVGQSAQVRDWLDLYGGESLMQQRQKTAVAFSTYHAAHQTLEKRRTSERERLQQLDLLTYQVQELGAANLSDVQEMELLTQERERLNHVVDLQQMSYKVYQALYQNEDETPTASDLLGDSDATLTNMVEFDSQLQPLLELVRDAVTTVMEVGRQISAYGEGLEADPQRLEEVEERMRELKQICRKYGPTLTEAIAYYERIQIELAELNNSEQSIETLEQQEQVCLQHLNQVSQQLTQLRRQTAASLESHLLAELKPLAMEKVKFQVEIAPTSPTATGADKITFMFSPNPGEPIQPLTEIASGGEMSRFLLALKACFNQNDGAETMVFDEIDVGVSGRVAQAIAEKLHQLSQSYQVLCVTHQPLVAAMADSHFRVDKQVTHKNGNTEQRTVVRVTSLDNLSTRREELAQLAGGKSANEAIAFAGSLLLQAANHRRQEQS
>NC_019771.1|WP_015212512.1|303688_304942_+|inorganic-phosphate-transporter
MIIIAFLAFYVAFNLGANDVANAMGTSVGSKAITLKQAIIIAGILEFTGAVLFGHGVTETLGTKIANPELFTTTPQTLLLGMVTVLIAAGIWLQIATSRGLPVSSSHAVVGAIAGFTWVALGIEAIDWSSIGLITIGWILTPVISGIVAAFFYSLIQRWILAQPHPVAQLQEWIPWLSTILITIFGVIVLPTLTQPLTNYLIKKVGLNIPTHDIPIFTGAAAAIGLTLYSWKKLQDNQKSFSQSPIPNPVESLFARFQLLSACFVAFAHGSNDVGNAIAPLAVISYINQTGSVPINGLTIPIWIMILGGLGIVAGLAIWGQKVIATIGENIISLQPSSGFCAELATAATILLASRFGLPVSTSHALVGGVVGIGLVQNLKSIKFQTLQGIASAWVITVPISAIISATIFSIIRMILN
>NC_019771.1|WP_015212513.1|305570_307946_+|EamA-family-transporter
MGRFEKRPDNPRIRGDLSRAAENALWDVVEDLENLQKNVLKSLQDDVKRLESEKTRLANDIQRLTEEKEKLQQARQITEQQVLIRQLAEVLAKHISSQLQSSLKTLAAQSIEGESSERVTLRSAEVNPLAASQINENVGQMLDNLDDSVTIAFSSLQQELKNYQSHLSQQLSRMYDQQQEGEDILAEFINRLKGELDKTRETTSLKVLTGGAPTVLQLNEPYKNGFLEKSPERIISEPISLFPQESPKSENSSSTEAVVTSPPTQENTPEPMSFKTPDSFTKQSTSELSTQENTPEPISVLTPDSSTKQSTSESSTQENTPEPMSFKTPDSSTKQSTSESSTQENTPEPMSFKTPDSSTKQSTSELSTQENTPEPMSFKTPDSFTEQSTSESSTQKTTPEPISVLIPDSSPKQSKYSPPLTPRRETTTRRERSRSSPNWSPVQVGFLLVVLSTVMSSLYNVAVKALFYKGSDFLGNFETQQLIAPTLGNIFLILMLRLLVVVPLMLLLAPILHPSVWQDLQNLFDSVGRNATSNQAKTKQVLILSVVGGCLLFLSQVLIYIAIGKVLTGIAVALFFIYPLVNGLLAWFLFRERPNLFSAGAIFGIFCGELLILGSYSNGMNNTSLGIISGIMSGMAFAVYVILTRLCAPKLHPVSFALINFATMLLLSFICLMVPLPSDWSLAIRSANLLEVILSAFMLGVLTLCGYLFNNFGIRKLGGPPSAIIGALVPVVTVIFAGLMIQEKLDIVQIMGVLLVTGGAVAISFEKMRNHLQSSNTNNQRMKNNETKYRG
>NC_019771.1|WP_015212514.1|308342_309242_+|heterocyst-differentiation-master-regulator-HetR
MSNDIDLIKRLGPSAMDQIMLYLAFSAMRTSGHRHGAFLDAAATAAKCAIYMTYLEQGQNLRMTGHLHHLEPKRVKIIVEEVRQALTEGKLLKMLGSQEPRYLIQLPYVWMEKYPWQPGRSRVPGTSLTSEEKRQIERKLPKNLPDAQLVTSFEFLELIEFLHKRSQEELPPHHQMPLSEALAEHIKRRLLYSGTVTRIDSPWGMPFYALTRPFYAPADDQERTYTMVEDTARYFRMMKDWAERKANAMRAVEELDIPLEQMEQAMEELDEIIRAWADKYHQDGGMPMILQMVFGNQDD
>NC_019771.1|WP_015212515.1|309550_310165_-|hypothetical-protein
MLESKKEISNFQNQNRNYVLRILTVPVVAIAGFLINVIPSIAVTDSYRNDYRVCAAQLLSVGVTAQAASQGCSTALRPKDLSSCVAQIKKQTEIASTEALYSCSKARRPQELAACVVGISKSTQKAIDPTTLTYCGRSLLPVTFAQCVVGLRKEIDLTPIQSLNTCINASDRIISIGEGSTTAPGSNPSLETAPMPSTPSGSGI
>NC_019771.1|WP_015212516.1|310705_311314_+|30S-ribosomal-protein-S4
MSRYRGPRLRIVRRLGDLPGLTRKSPRRAYPPGQHGQNRKKRSEYAIRLEEKQKLRLNYGLTEKQMLRYVRKARRVTGSTGQVLLQFLEMRLDNTVFRMGMAPTIPAARQLVNHGHVTVNGRVVNIASYQCRPGEEIAVRNKEASKKLVEANLQYPGLANLPNHLEFDKNKLTGKVNSVIEREWVALQVNELLVVEYYSRQA
>NC_019771.1|WP_015212517.1|311389_312376_-|GTP-3',8-cyclase-MoaA
MNQVDYLRISLIDRCNFRCQYCMPEGAELNYILKQQLLSDEEILTLIQEVFIPLGFTRFRLTGGEPLLRPSVVDLVSKIANLPQTQDLAMTTNGFLLAPIAQNLYDAGLRRINISLDSLEPDTFEQIIGNHGRGRWQQVWEGIQAAYCVGFDPLKLNVVVIPGVNDHEILNLAALTIDKQWHIRFIEFMPIGNEYLFSDRGWISSADLRYSIREHWGLTESQIYGNGPADVFQIPGAKGTLGFISQMSECFCDRCNRVRLSADGWLRPCLLNETGQIDLKTSLRAGISTAQLRQQVKQLLNIKAEINFKQRDSGSSGTYTRTMSQIGG
>NC_019771.1|WP_015212518.1|312605_313073_-|SsrA-binding-protein-SmpB
MSDKKEGFKVISDNRQARYLYEIIETYEAGIQLTGTEVKSIRAGKVNLQDGYALLRNGEAWLINIHISPYTSSGQYFNHEPRRTRKLLLHRQELRKLIGKVEQQGLTLVPLKMYLQRGWVKVSIALGKGKKLHDKRESLKRRQDQRDIQRAMKSY
>NC_019771.1|WP_015212519.1|313717_314401_+|response-regulator-transcription-factor
MPLKILVVDDDLGTRLSISDYLELSGYAVIMADDGQEALAMVEENQPDLIVTDIVMPRMNGYELVRRVRKQSEFRLLPVILLTARTKTQERILGYQSGCDLYLPKPFELEELAAAIRNLLERSQIIQSEYRFSHQENLDASHSTKTLDSHNSLSTQIHISPVLSSLTAREQEVLELLTHGFSNADMGHQLHLSPRTVEKYVSSLLRKTSTSNRAELVRFAMKHGLVE
>NC_019771.1|WP_015212520.1|314506_314986_-|low-molecular-weight-phosphotyrosine-protein-phosphatase
MPYKLLFVCLGNICRSPSAENIMNLLVDQADLGNSIYCDSAGTSSYHIGSAPDRRMSAAAVTKLGIKLRGQARQFTKSDFQEFDLILAMDKDNYENILAVDLSGQYHHQVRLMCDFCSRHTLKEVPDPYYGGTEGFNQVIDLLIDACEGLLDYVKSQQV
>NC_019771.1|WP_015212521.1|315032_315383_-|YbaB/EbfC-family-nucleoid-associated-protein
MTSGKGQGFGFGLGKMKELADAFKKAQQVQEGAKLLQEQLEKMEIQGESGGGLVKVIVSGNQEPKRVEIAPEALAEGVEVLSDLVTAAMKDAYNKSTATMRESMEELTSGLELPGF

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Crispr_ID: NC_019771_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_4

739352-739766

TypeV-U5

A:N

Consensus_repeat	Method
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	PILER-CR
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	CRISPRCasFinder
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	CRT

5 spacers

c2c5_V-U5

The CRISPR arrays of NC_019771_4

>merge|NC_019771|4|739352-739766|PILER-CR,CRISPRCasFinder,CRT
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAGCTTTGTACGAGCAGACAACATTTTAGTTTTCCTCCAAAGTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAGTCACCCCGCTGCATCCATTCCTCTACTTTTTCAAAAGTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAGTTTTATGATCGAAGAAATCAAGGATAGCTGTACCTCAAGTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAGTCCACAATCCGCGTTTGCGATCGCAATTAGCACCCCCCGGTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAGAAGCGAGAGAAAGAAATACCAGAAACAGAATATATCGTTGAGGTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG

>NC_019771|4|3|739352-739766|PILER-CR
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	CTTTGTACGAGCAGACAACATTTTAGTTTTCCTCCAAA
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	TCACCCCGCTGCATCCATTCCTCTACTTTTTCAAAA
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	TTTTATGATCGAAGAAATCAAGGATAGCTGTACCTCAA
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	TCCACAATCCGCGTTTGCGATCGCAATTAGCACCCCCCG
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	AAGCGAGAGAAAGAAATACCAGAAACAGAATATATCGTTGAG
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG

>NC_019771|4|4|739352-739766|CRISPRCasFinder
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	CTTTGTACGAGCAGACAACATTTTAGTTTTCCTCCAAA
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	TCACCCCGCTGCATCCATTCCTCTACTTTTTCAAAA
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	TTTTATGATCGAAGAAATCAAGGATAGCTGTACCTCAA
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	TCCACAATCCGCGTTTGCGATCGCAATTAGCACCCCCCG
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	AAGCGAGAGAAAGAAATACCAGAAACAGAATATATCGTTGAG
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG

>NC_019771|4|2|739352-739766|CRT
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	CTTTGTACGAGCAGACAACATTTTAGTTTTCCTCCAAA
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	TCACCCCGCTGCATCCATTCCTCTACTTTTTCAAAA
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	TTTTATGATCGAAGAAATCAAGGATAGCTGTACCTCAA
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	TCCACAATCCGCGTTTGCGATCGCAATTAGCACCCCCCG
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG	AAGCGAGAGAAAGAAATACCAGAAACAGAATATATCGTTGAG
GTTTCAACTACCATCCCGACTAGGGGTGGGTTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015212844.1\|730258_732007_+\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|223363
NC_019771.1\|WP_015212853.1\|744112_744949_+\|4-hydroxy-tetrahydrodipicolinate-reductase	unknown	unknown	gnl\|CDD\|234595
NC_019771.1\|WP_015212845.1\|732089_733454_+\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|341142
NC_019771.1\|WP_015212858.1\|748393_748750_-\|YtxH-domain-containing-protein	unknown	unknown	gnl\|CDD\|227313
NC_019771.1\|WP_015212856.1\|746550_747360_-\|TPM-domain-containing-protein	unknown	unknown	gnl\|CDD\|377378
NC_019771.1\|WP_042464520.1\|747727_748306_-\|DUF948-domain-containing-protein	unknown	unknown	gnl\|CDD\|377605
NC_019771.1\|WP_150110987.1\|734424_736296_+\|DUF262-domain-containing-protein	unknown	unknown	gnl\|CDD\|226003
NC_019771.1\|WP_015212840.1\|724727_725768_+\|CHAT-domain-containing-protein	unknown	unknown	gnl\|CDD\|378942
NC_019771.1\|WP_015212843.1\|729463_730210_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015212851.1\|741125_742307_+\|RtcB-family-protein	unknown	unknown	gnl\|CDD\|376465
NC_019771.1\|WP_015212842.1\|726688_729421_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|226581
NC_019771.1\|WP_015212859.1\|748820_749189_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015212852.1\|743023_743956_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|273359
NC_019771.1\|WP_015212846.1\|733546_733843_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015212849.1\|736936_738865_+\|hypothetical-protein	c2c5_V-U5	-	gnl\|CDD\|273793
NC_019771.1\|WP_015212850.1\|740168_740918_-\|HAD-family-phosphatase	unknown	unknown	gnl\|CDD\|223710
NC_019771.1\|WP_015212855.1\|745814_746444_-\|precorrin-8X-methylmutase	unknown	unknown	gnl\|CDD\|180325
NC_019771.1\|WP_015212841.1\|726064_726538_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015212847.1\|733936_734251_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015212854.1\|745080_745788_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015212844.1\|730258_732007_+\|N-6-DNA-methylase	gnl\|CDD\|223363	COG0286, HsdM, Type I restriction-modification system methyltransferase subunit [Defense mechanisms].	1.17651e-47
NC_019771.1\|WP_015212853.1\|744112_744949_+\|4-hydroxy-tetrahydrodipicolinate-reductase	gnl\|CDD\|234595	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional.	2.11176e-108
NC_019771.1\|WP_015212845.1\|732089_733454_+\|restriction-endonuclease-subunit-S	gnl\|CDD\|341142	cd17253, RMtype1_S_Eco933I-TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit TRD-CR, similar to Escherichia coli O157:H7 EDL933 S subunit (S.Eco933I), Escherichia coli O104:H4 2009EL-2071 S subunit (S.Eco2071ORF3585P) TRD2-CR2, and Streptomyces species SirexAA-E S subunit (S.SspAAEORF2129P) TRD1-CR1 and TRD2-CR2. Escherichia coli O157:H7 EDL933 S subunit (S.Eco933I) recognizes 5'... CACNNNNNNNCTGG ... 3' and Escherichia coli O104:H4 2009EL-2071 S subunit (S.Eco2071ORF3585P) recognizes 5'... RTCANNNNNNNNGTGG ... 3'. The recognition sequence of Streptomyces species SirexAA-E S subunit (S.SspAAEORF2129P) is undetermined. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. For example, S.Eco2071ORF3585P TRD1 recognizes RTCA/TGAY and S.Eco2071ORF3585P TRD2 recognizes CCAC/GTGG. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	2.17315e-86
NC_019771.1\|WP_042464520.1\|747727_748306_-\|DUF948-domain-containing-protein	gnl\|CDD\|377605	pfam06103, DUF948, Bacterial protein of unknown function (DUF948). This family consists of bacterial sequences several of which are thought to be general stress proteins.	2.37144e-05
NC_019771.1\|WP_015212840.1\|724727_725768_+\|CHAT-domain-containing-protein	gnl\|CDD\|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	2.59079e-05
NC_019771.1\|WP_015212849.1\|736936_738865_+\|hypothetical-protein	gnl\|CDD\|273793	TIGR01766, Putative_transposase_MJ0751, transposase, IS605 OrfB family, central region. This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions].	0.00783498
NC_019771.1\|WP_015212856.1\|746550_747360_-\|TPM-domain-containing-protein	gnl\|CDD\|377378	pfam04536, TPM_phosphatase, TPM domain. This family was first named TPM domain after its founding proteins: TLP18.3, Psb32 and MOLO-1. In Arabidopsis, this domain is called the thylakoid acid phosphatase -TAP - domain and has a Rossmann-like fold. In plants, the family resides in the thylakoid lumen attached to the outer membrane of the chloroplast/plastid. It is active in the photosystem II.	4.87913e-09
NC_019771.1\|WP_015212850.1\|740168_740918_-\|HAD-family-phosphatase	gnl\|CDD\|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	4.87341e-50
NC_019771.1\|WP_015212858.1\|748393_748750_-\|YtxH-domain-containing-protein	gnl\|CDD\|227313	COG4980, GvpP, Gas vesicle protein [General function prediction only].	4.94257e-27
NC_019771.1\|WP_015212851.1\|741125_742307_+\|RtcB-family-protein	gnl\|CDD\|376465	pfam01139, RtcB, tRNA-splicing ligase RtcB. This family of RNA ligases (EC:6.5.1.3) join 2',3'-cyclic phosphate and 5'-OH ends. They catalyze the splicing of tRNA and may also participate in tRNA repair and recovery from stress-induced RNA damage.	0
NC_019771.1\|WP_015212852.1\|743023_743956_+\|DMT-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	5.23835e-10
NC_019771.1\|WP_015212855.1\|745814_746444_-\|precorrin-8X-methylmutase	gnl\|CDD\|180325	PRK05953, PRK05953, Precorrin-8X methylmutase.	3.03827e-148
NC_019771.1\|WP_150110987.1\|734424_736296_+\|DUF262-domain-containing-protein	gnl\|CDD\|226003	COG3472, COG3472, Uncharacterized conserved protein [Function unknown].	5.1277e-115
NC_019771.1\|WP_015212842.1\|726688_729421_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|226581	COG4096, HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	2.36416e-170

>NC_019771.1|WP_015212849.1|736936_738865_+|hypothetical-protein
MSVITIQCRLVAEEDSLRQLWELMSEKNTPFINEILLQIGKHPEFETWLEKGRIPAELLKTLGNSLKTQEPFTGQPGRFYTSAITLVDYLYKSWFALQKRRKQQIEGKQRWLKMLKSDQELEQESQSSLEVIRNKATELFSKFTPQSDSEALRRNQNDKQKKVKKTKKSTKPKTSSIFKIFLSTYEEAEEPLTRCALAYLLKNNCQISELDENPEEFTRNKRRKEIEIERLKDQLQSRIPKGRDLTGEEWLETLEIATFNVPQNENEAKAWQAALLRKTANVPFPVAYESNEDMTWLKNDKNRLFVRFNGLGKLTFEIYCDKRHLHYFQRFLEDQEILRNSKRQHSSSLFTLRSGRIAWLPGEEKGEHWKVNQLNFYCSLDTRMLTTEGTQQVVEEKVTAITEILNKTKQKDDLNDKQQAFITRQQSTLARINNPFPRPSKPNYQGKSSILIGVSFGLEKPVTVAVVDVVKNKVIAYRSVKQLLGENYNLLNRQRQQQQRLSHERHKAQKQNAPNSFGESELGQYVDRLLADAIIAIAKKYQAGSIVLPKLRDMREQISSEIQSRAENQCPGYKEGQQKYAKEYRINVHRWSYGRLIESIKSQAAQAGIAIETGKQSIRGSPQEKARDLAVFTYQERQAALI
>NC_019771.1|WP_150110987.1|734424_736296_+|DUF262-domain-containing-protein
MIITSEPPMHSISTFDITKYPLFDLLKDVKTGRIQLPDFQRDWVWDDARVRRLLASISLAYPIGAVMMLQQSNQQGQFKPRLINNVKKPQNHSPNLLILDGQQRLTTLFMVLLSEQPVIIKDQKSQKLIKKWYYLDIAKCLDYNSERRSAILAFSESKQLRSFGGEIIDCSTPEKEYEAGLFPLSKIFFFSEWRSKYSKYWQYDPQKLELIDTLELEVLKKFEHYQIPVIQLRDSLPKEAVCQVFEDTNTSGCDLNFFDLMSSSYCANDFSLRDDWKLREAQFQQFKVLRLVRNTDFLQTVALLAGYARRMEAIKKGSNLEKLPAVSCGRSDVLKISITEYSHWANKVTAGFEEAARFLHGQKIFDATDLGYPIQIVALAAILTVLGEKSRSVKSRSMLERWFWCGMFGEMYTGWHETRTGKDLVEIPLWLKHGDSLPSTIREANFTHERLLTVRKRYGAVYQGLSALLRLSGAIDWITGEEINDVLYFEEKIDSHHIFPVAWCRKQGIDPKKYNCLVNRTPLSAKTNKKIGSKAPSVYLKELEMSGISPQRLDEILLSHVIDPETLRRDDFDDFFQARSKALLELIGQAMGKCLDMEYLDEFSLKYHNGYASPILPETLLRN
>NC_019771.1|WP_015212847.1|733936_734251_+|hypothetical-protein
MLVRLSPNPEEQRIDTIRHLPLEPMEYCQRWVDVDPSRGYRKACIHALAKATGLSPHTIKDWGTNFDRRPHYVPFLLRQADLLNQFKQLVITQQIILPPNFPTN
>NC_019771.1|WP_015212846.1|733546_733843_+|hypothetical-protein
MIDSKPLSTQYINDVLSRQPLEPLEYCQRWVEIPPEERGYRKACIAALAEATALSPRTINDWGANFERRPDHVLHVLRMADMLNQIRKIVLPPDYPQK
>NC_019771.1|WP_015212845.1|732089_733454_+|restriction-endonuclease-subunit-S
MLIDKQKILPHGWSYVTLQNVCDIIGGSQPPKECFVYEPKPGYIRLIQIQDYKSDKNKTYIPEALAKRFCTEDDIMIGRYGPPIFQILRGLKGSYNVALMKANPKNDKVLNKGYLYYFLQNQTLLNYIISNSSRTAGQDGVRKELLDEYPIPLPPLPEQKRIAVILEKCDRLRRTRRYSIQLSETFLQSVFLEMFGDPATNPMGWDKSFLEQISEVQGGIQLSQKRENLPLKLPYLRVANVYRNKLELSEIKTISLTENEFRRVKLQKNDILIVEGHGNTEEIGRCAVWNGSIENCVHQNHLIRVRVNPKIINSAYLSYYINNSGGRKYFHNSSNTTSGLNTISTGIVKQCIVPLPPLPLQEKFAQIVQKHDRFRTQQREAERQAEHLFQTLLHRAFRGELTSSDCNDVDISALSAETHPQQPKPKSTDKAENFPIPATQRQTNALQLTLPGLE
>NC_019771.1|WP_015212844.1|730258_732007_+|N-6-DNA-methylase
MLTDPNLKSKVDLLWDKLWTGGLSNPMDAIEQFSFLLFLKRLDETEDLNERQAKRRKEDYQPKIPAEMRWRNWTQKKAEDALNHVKNKVFPWLKEMGNSDNEEENEEGNKQETNEDKSSFSEYMQTAEFKINKPSLLIEACKSIDEMKISEQNQDVQGDLYEYLLNKLSIAGRNGQFRTPRHIIRMMVEMVEPKPTDRIGDLAAGTCGFPVNAYQYILEKNTSPEILFDEKGNKHLVGDLLTPEESEFLQTEAFTAYDNDSGMTMLRIGSMNFMLHGIEQPRFFAKDTLSKRFDDENTLDLVLMNPPFKGAVDAADVHPKLAGLSKKSELLFLHLILRVLDMGGRCAVIVPDGVLFGSSKAHVEIRKKIIEENRLDGVVSMPSGVFKPYAGVSTAVLLFTRGGTTDRVWFYDMEHDGFSLDDKRQPVTENDIPDILDCWQNRFNADVTQQNEERLAELKKQIAPLKAERLLLHKEINRLSFENAVAPADDEATSQALETDKQKLALLHEKISPLQNEINRLNRQFWVTKAQVRGNKYDLSASRYRQVEQDEVFYDVPQVTLERLLKLEDVMGAEVRELEILL
>NC_019771.1|WP_015212843.1|729463_730210_+|hypothetical-protein
MSSTLNDRFDKTIKSLWDKIGRFGSWTSDLEKRKYIHEKLQYFHATHSDDNEHITDIFMSLPSGYNLLKSALEWESPKIGKESLPYKLRETHIVRGIQWKLVIAHGGFETIAKTLMNDQNRGFHPSTIQQFIEKCDLPIYNSLKPPIGTHKLDLWLNKPVAENEHNAIITFLGLERGDATIIKNWIIESQEIDSWDKVVQLSKALRNATAHGALSATKVFDWDLVDKMEIITENLGEIAIAGLNKLIE
>NC_019771.1|WP_015212842.1|726688_729421_+|DEAD/DEAH-box-helicase-family-protein
MSANEANTRKQLIDPALTLAGWNIKDHNQVGLEIPVDGYNAEPWNGVTDYCLYQPNGEVIAVVEAKRQSSDPKIAQTQVEYYVKEIEKHQSFRPFAFMTNGEEIYFWDVGNSAKRQVAGFFSPSDLENLLYIRQNQIALSSIPINTQIAGRDYQQEAIRRVCETFDQGKRRTLLVMATGTGKTRTAMAIIDLFLKANQSRKILFVADRDNLVKQALEDGFMEHIPHEPCDRIYSYNIDKTKRLYVVVEKTLRNSYKNFSPAFFDLIIFDEAHRSIFNLFQEVMEYFDGRMIGLTATPAGFIDRNTFNTFHCFDGIPSFLYTYKQAIEEKNLVDFSLYQAQTKFQSEGIKGAKLSEEEQNVLIAQGTDPDNIDFSGTDLEKKVSNKDTLRKQWEEIMEHCHKDESGQLPAKTIVFALTQKHALRLSTTFEEMYPQYSDLVRVITHKTEYKGKLTGNFKKEDMPRIAISVDMLDTGIDVPEIMNLVFMKPVQSQIKLWQMIGRGTRNQKACKKLEWLPNRTKQEFLIIDFWENEFEAKAQTEVAQTIPVLQRIFNTRLDLLELYLHNQESPDCQAVIASLREQITQIPIDSFTVKKKIVDIAEAWTDLFWNYITKDKLKSLRFKVAPLLRFVPGVEIAAATFTSKVERLKLEIQTEGAKPDTVQSIAEDVSRLPDFIHQDKRKQDAIKLCLSSRLNNATVKELNQIIANLAEEMKNRRQRPSIFLELDLADFVATRGFITVGEGGEQVYVEEYKKRVEEKINVIVDDHPTIKAIQEGEAVTDWQLIELERTLRQGLGGGNIQLSESNIRKAYGLKANSLLAFLRHLLDLDAIPDYEEVVKRQFEEFIAKHQYNANQINFLRAVQSVFLQKRRLEVADLYEGALARFGKNAVDRFFSDDEVDDLLAFTELLAA
>NC_019771.1|WP_015212841.1|726064_726538_+|hypothetical-protein
MTDSSVLIMKMRQQILSLSLTLYLAASQNNDTEEEIKIPPLIISIAKRGLALHEEFGGGRNIAVAKGLTGQRPLTLEDLNKIVDFFETHDPDYNDPGWSSARNPSGAWIRWCLMGGNGSWAREMKEEIEKDKNPHRFRFVVPLEQPIPKTHQPSQGF
>NC_019771.1|WP_015212840.1|724727_725768_+|CHAT-domain-containing-protein
MKNILILSANPKNTANLRLDEEVREIKNTLQLSPHRDEFQIITESAVRVDDLTRFLSHHQPTIVHFSGHGSGTDGLALEDNSGQMQLVSTQALAKLFDLFQEQVECVLLNACYSEEQATAIHQHIDCVVGMNQAIGDKAAIKFSIGFYTGLGAGRNYEDCFQIGCTNIDLQGIPEYATPEIKIRRRHYQTEKPANPVKSDKNNGVNNDNKSGQNRSVSIGGSVTGGAVITGDSNTANINFQQVSLPAPASVNIEAELNALREILAKLETSDRRKIDNAFEEAQEELNKPQPDKDEMGNALNRALKYAKKAGEFASVIAKLQPHLTKITAWLGADWHDLLSLVNLTI
>NC_019771.1|WP_015212850.1|740168_740918_-|HAD-family-phosphatase
MSLKAVLFDFNGVIIKDEPIHLQLIDEILIQENIQPQRVNERQASLGRSDACGKQSYRDYFQDLLKNRGRVITEEYLSDLLNRKAQAYVLELEKLEKLPLYAGVDDLIFQARSHNIKLGLVSDSLLQEIQLVLERAKLTEYFQIIVTGDDIATSKPQPEGYLLAVEKLNQAYPDLNLQPQECLAIEDTPAGIQAAKRAQMQVVGVANTYPFHMLQRQANWTVDYLTDLELDRVQEVFLQKEVKTTLPEC
>NC_019771.1|WP_015212851.1|741125_742307_+|RtcB-family-protein
MPYEQLGINTPSPVLSWANHPLGSDEIKMAKNVASLPFVFKHVALMPDVHLGKGALVGSVIATKETIIPAAVGVDLGCGMSAIKTQFKGEQLEGKLKKIRLDIEAAIPTGFNENKDVEKSASNWQRWRDFKDLHRGVQDLESKAMKQMGSLGGGNHFIEICLDTENQVWLMLHSGSRNIGNKLAQCHINTAKELAKMAGEKLPDPDLAYFVAGTPEFQAYWKDLQWAQNYALFNRDVMMARFKRIVEKHLVGGKVTKPLLEVNCHHNYAEKEVHFGEDVYVTRKGAVRAQTEDYGIIPGSMGAKSFIVKGKGNAHSFCSCSHGAGRIMSRSKAKNVYTLDDLIEQTQGVECRKDTGVLDEIPGAYKPIEQVMENQADLVEIVATLKQVMCVKG
>NC_019771.1|WP_015212852.1|743023_743956_+|DMT-family-transporter
MILFFSNIFSQWVTAAVRLKIFTQKLTQNHLRIQGIILFVIINIIWGTTFPLIEKTVGSLSPSVLIATRFCVAALLFSGNLRGLNKLILRDGLLLGLVFFAYLAIETIALESIHANRAAFIVSLSAILVPLLGSFFGRRLPGKTFFSAGLAVIGIGVMFWGGGVLGIGDLLMLGDAVLYAVYTLILEQIAPRHPSLSLTSIQLFVIAILGALWSNTSLIDEMNIINENWGVIFYLGLVATAIVIWLQTVAQQWIRSEEAALLYTLEPIFSAIFSFLILGEQLGLSGFIGATFVLSAIVFSQKPQDLQLDT
>NC_019771.1|WP_015212853.1|744112_744949_+|4-hydroxy-tetrahydrodipicolinate-reductase
MTNQSTIPVIVNGAAGKMGREVIKAIAQAPDMILMGALDTSPEHQDKDAGELAGLSEPLEVPITNQLEPMLGYVAGERQMAPGVMVDFTHPDAVYDNVRSAIAYGIRPVVGTTGLSPQQIQNLTDFAEKASTGCLLIPNFSIGMVLLQQAAVTASQYFDHVEIIELHHNQKADAPSGTAIQTAQLLAELGKTFNPPQVEETEKIPGARGSLADEGIRIHSIRLPGLIAHQEVIFGAAGQIYTLRHDTSDRSCYMPGVLLAIRKVNQLKSLVYGLEKIL
>NC_019771.1|WP_015212854.1|745080_745788_+|hypothetical-protein
MLVPLTRSKFEQIMPLIATGMQYKYYWGKSASFLQRLLISVVSVVVILLVQLLFKLDFSVIFIFGVFSAFFWLWYPVFQASTRNAKCRRYKYSGFFRGRVLDWWITDKLTGKQETVNNKGDLVIIENREKRINLEIGDDTGFTVEFDAPLRPAHKAIARGQIAEMIVMSNRPDLSSIEEFSNIYIPSRNLWVSDYPYVREDLFNEVSLRLRENQQEKPRRRRRPESQRSREDDQY
>NC_019771.1|WP_015212855.1|745814_746444_-|precorrin-8X-methylmutase
MEWHVTDAQSLAIIDSEIGDHVFSPAEYEIVRRVIYATSDFEYKSLIRFSEHALQAGAAALAARTTIVVDAPMVQVGIAYEIQNTFANPVYCSMEALTRPQKEKTRSAWGIETLAKRYPEGIFVVGQAQTALTALVDLIEAEEIRPALIIATPAGFINVDTDKERLQESLVPYITIDSRKGNAVVAAAIVNGLVDLAWQAYGQDRNGGS
>NC_019771.1|WP_015212856.1|746550_747360_-|TPM-domain-containing-protein
MQLCFWQRFLVSIAVLCFTASIWALPSPSALAYENPDLLPNIFTPVVDLAKTLPDPQEEKLVQELEQFETDTGWKLRVLTQYDRTPGRAVIKYWGLDDKSILLVADARGGNILSFSVGDAVYEFLPRTFWIELQTRFGNLYFVREQGEDQAILQALDSVKGCLLKGGCNVVPGLPREQWILTLITSAIGGVICGFAAQPRNNKQVFAWQWALIFSPLWGILFIAFGIGPVVTRTSDWVPLVRNISAFLIGVLVAYLSPGFSRPSSNTES
>NC_019771.1|WP_042464520.1|747727_748306_-|DUF948-domain-containing-protein
MIDPLFWLGMSTFLVAASLTAVLVALIPTLQELARAARSAEKFFDTLSRELPPTLNAIRNTSLELTDLTDDVSEGVKSASQVVKQVDQSLDIAKKQAHNIQISTRSLAVGVKAAWKTFTRQKPARRSPERLPMNEKSELTLREREALRQENRRTQTELYRPNHSYSEAINWESDFNDENLISKSAPSEDWSD
>NC_019771.1|WP_015212858.1|748393_748750_-|YtxH-domain-containing-protein
MSNNRSGLFIGGLMLGATIGALTGLLAAPRTGRETRKLLKKSADALPELAEDLSTSVQIQADRLSASALRNWDDTLERLRIAIAAGVDATQRESEALKRQNPADPENTDSLTQHLEHS
>NC_019771.1|WP_015212859.1|748820_749189_-|hypothetical-protein
MVTVVVLINILISLILLYVARLMWRIKQKLGIIADSLNSYERVSHAVLYTAPENIYTGQQEIYNLRQKHQKLKLQVQQVQQILSLVVLGRKMWQRFFWQPDSTSRNKNSPTYQLINQSNFTD

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Crispr_ID: NC_019771_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_5

854041-854148

Orphan

A:N

Consensus_repeat	Method
AAACTATCTATAAATTACCATCCTGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019771_5

>merge|NC_019771|5|854041-854148|CRISPRCasFinder
AAACTATCTATAAATTACCATCCTGTTAATCTTATAATCGGTGGATATCCTGATTCAGACGAATACAACTTTCATCATCAACAAACAATCTATAAATTACCATCCTGT

>NC_019771|5|5|854041-854148|CRISPRCasFinder
AAACTATCTATAAATTACCATCCTGT	TAATCTTATAATCGGTGGATATCCTGATTCAGACGAATACAACTTTCATCATCAAC
AAACAATCTATAAATTACCATCCTGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015212964.1\|868752_871290_+\|S-layer-family-protein	unknown	unknown	gnl\|CDD\|368641
NC_019771.1\|WP_015212946.1\|838921_840157_+\|PDZ-domain-containing-protein	unknown	unknown	gnl\|CDD\|177681
NC_019771.1\|WP_015212952.1\|845185_847570_-\|dynamin-like-GTPase-family-protein	unknown	unknown	gnl\|CDD\|223771
NC_019771.1\|WP_015212953.1\|847741_850225_-\|U32-family-peptidase	unknown	unknown	gnl\|CDD\|223896
NC_019771.1\|WP_042464545.1\|861181_862111_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015212962.1\|865340_866066_+\|COG4280-domain-containing-protein	unknown	unknown	gnl\|CDD\|226730
NC_019771.1\|WP_015212959.1\|859776_861222_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|379114
NC_019771.1\|WP_015212954.1\|850401_852930_+\|Eco57I-restriction-modification-methylase-domain-containing-protein	unknown	unknown	gnl\|CDD\|377679
NC_019771.1\|WP_015212951.1\|844722_845094_-\|KGK-family-protein	unknown	unknown	gnl\|CDD\|370166
NC_019771.1\|WP_015212947.1\|840185_840971_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293813
NC_019771.1\|WP_015212950.1\|844450_844696_-\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|372995
NC_019771.1\|WP_015212957.1\|856256_858368_-\|TIGR00300-family-protein	unknown	unknown	gnl\|CDD\|224827
NC_019771.1\|WP_096713183.1\|854303_854744_-\|GUN4-domain-containing-protein	unknown	unknown	gnl\|CDD\|319862
NC_019771.1\|WP_015212949.1\|843008_844454_+\|glycoside-hydrolase-family-13-protein	unknown	unknown	gnl\|CDD\|200477
NC_019771.1\|WP_042464548.1\|863127_863322_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015212955.1\|853099_853876_-\|Uma2-family-endonuclease	unknown	unknown	gnl\|CDD\|368559
NC_019771.1\|WP_015212958.1\|858627_859770_+\|DUF4145-domain-containing-protein	unknown	unknown	gnl\|CDD\|372658
NC_019771.1\|WP_015212961.1\|863396_865055_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NC_019771.1\|WP_015212948.1\|841380_842859_+\|site-2-protease-family-protein	unknown	unknown	gnl\|CDD\|100081
NC_019771.1\|WP_015212963.1\|866155_868687_+\|S-layer-family-protein	unknown	unknown	gnl\|CDD\|225751

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015212964.1\|868752_871290_+\|S-layer-family-protein	gnl\|CDD\|368641	pfam05860, Haemagg_act, haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins.	2.12267e-28
NC_019771.1\|WP_015212946.1\|838921_840157_+\|PDZ-domain-containing-protein	gnl\|CDD\|177681	PLN00049, PLN00049, carboxyl-terminal processing protease; Provisional.	5.62912e-141
NC_019771.1\|WP_015212952.1\|845185_847570_-\|dynamin-like-GTPase-family-protein	gnl\|CDD\|223771	COG0699, COG0699, Predicted GTPases (dynamin-related) [General function prediction only].	7.31017e-43
NC_019771.1\|WP_015212953.1\|847741_850225_-\|U32-family-peptidase	gnl\|CDD\|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	3.03112e-117
NC_019771.1\|WP_015212962.1\|865340_866066_+\|COG4280-domain-containing-protein	gnl\|CDD\|226730	COG4280, COG4280, Predicted membrane protein [Function unknown].	3.61216e-79
NC_019771.1\|WP_015212959.1\|859776_861222_+\|ATP-binding-protein	gnl\|CDD\|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	3.10227e-16
NC_019771.1\|WP_015212954.1\|850401_852930_+\|Eco57I-restriction-modification-methylase-domain-containing-protein	gnl\|CDD\|377679	pfam06616, BsuBI_PstI_RE, BsuBI/PstI restriction endonuclease C-terminus. This family represents the C-terminus of bacterial enzymes similar to type II restriction endonucleases BsuBI and PstI (EC:3.1.21.4). The enzymes of the BsuBI restriction/modification (R/M) system recognize the target sequence 5'CTGCAG and are functionally identical with those of the PstI R/M system.	1.62466e-79
NC_019771.1\|WP_015212951.1\|844722_845094_-\|KGK-family-protein	gnl\|CDD\|370166	pfam08872, KGK, KGK domain. This presumed domain is found in one or two copies in cyanobacterial proteins. It is named after a short sequence motif.	2.86185e-45
NC_019771.1\|WP_015212947.1\|840185_840971_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293813	cd07727, YmaE-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis YmaE and related proteins; MBL-fold metallo hydrolase domain. Includes the uncharacterized Bacillus subtilis YmaE and Nostoc all1228 proteins.Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry. .	4.64107e-27
NC_019771.1\|WP_015212950.1\|844450_844696_-\|HNH-endonuclease	gnl\|CDD\|372995	pfam14279, HNH_5, HNH endonuclease. This domain is related to other HNH domain families such as pfam01844. Suggesting that these proteins have a nucleic acid cleaving function.	3.76999e-23
NC_019771.1\|WP_015212957.1\|856256_858368_-\|TIGR00300-family-protein	gnl\|CDD\|224827	COG1915, COG1915, Uncharacterized conserved protein [Function unknown].	0
NC_019771.1\|WP_096713183.1\|854303_854744_-\|GUN4-domain-containing-protein	gnl\|CDD\|319862	cd16383, GUN4, porphyrin-binding protein domain GUN4. GUN4 is a porphyrin-binding protein involved in chlorophyll biosynthesis regulation and intracellular signaling, found in aerobic photosynthetic organisms. It has been implicated in retrograde signalling between the chloroplast and nucleus. GUN4 can bind protoporphyrin IX (PIX) and magnesium protoporphyrin IX (MgPIX), substrate and product of the Mg-chelatase, as well as heme and cobalt protoporphyrin IX (CoPIX). It may play a role in protecting plants from reactive oxygen species (ROS)-mediated damage.	3.93132e-74
NC_019771.1\|WP_015212949.1\|843008_844454_+\|glycoside-hydrolase-family-13-protein	gnl\|CDD\|200477	cd11338, AmyAc_CMD, Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins. Cyclomaltodextrinase (CDase; EC3.2.1.54), neopullulanase (NPase; EC 3.2.1.135), and maltogenic amylase (MA; EC 3.2.1.133) catalyze the hydrolysis of alpha-(1,4) glycosidic linkages on a number of substrates including cyclomaltodextrins (CDs), pullulan, and starch. These enzymes hydrolyze CDs and starch to maltose and pullulan to panose by cleavage of alpha-1,4 glycosidic bonds whereas alpha-amylases essentially lack activity on CDs and pullulan. They also catalyze transglycosylation of oligosaccharides to the C3-, C4- or C6-hydroxyl groups of various acceptor sugar molecules. Since these proteins are nearly indistinguishable from each other, they are referred to as cyclomaltodextrinases (CMDs). The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NC_019771.1\|WP_015212955.1\|853099_853876_-\|Uma2-family-endonuclease	gnl\|CDD\|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	4.15503e-12
NC_019771.1\|WP_015212958.1\|858627_859770_+\|DUF4145-domain-containing-protein	gnl\|CDD\|372658	pfam13643, DUF4145, Domain of unknown function (DUF4145). This domain is found in a variety of restriction endonuclease enzymes. The exact function of this domain is uncertain.	2.84086e-15
NC_019771.1\|WP_015212961.1\|863396_865055_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	1.44804e-131
NC_019771.1\|WP_015212948.1\|841380_842859_+\|site-2-protease-family-protein	gnl\|CDD\|100081	cd06160, S2P-M50_like_2, Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the S2P/M50 family of RIP proteases use proteolytic activity within the membrane to transfer information across membranes to integrate gene expression with physiologic stresses occurring in another cellular compartment. In eukaryotic cells they regulate such processes as sterol and lipid metabolism, and endoplasmic reticulum stress responses. In prokaryotes they regulate such processes as sporulation, cell division, stress response, and cell differentiation. This group includes bacterial, eukaryotic, and Archaeal S2P/M50s homologs with additional putative N- and C-terminal transmembrane spanning regions, relative to the core protein, and no PDZ domains.	6.97331e-60
NC_019771.1\|WP_015212963.1\|866155_868687_+\|S-layer-family-protein	gnl\|CDD\|225751	COG3210, FhaB, Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion].	8.30904e-29

>NC_019771.1|WP_015212955.1|853099_853876_-|Uma2-family-endonuclease
MSETLADIAIPPQFPDHTQLPESDGTFVKNFQEHPQSIIITDSIIQTLQTLHPDGQFCIGQDCGIYWRETEPPEKGTVAPDWFYVPDVSPRLEGKIRRSYVLWREYIPPLIAIELASGNGDEERDTTPLTGLQAGQKPGKFWVYERIIRIPYYVIYEVNNDKLEVYHLVDFSYQKMQPNERGHYPIPPLGVELGLWQGSYLNNPEQLWLRWWDKKGNLLLLGKEEAQLQRLRTEQAERKAAQLAVRLREMGIDPDTID
>NC_019771.1|WP_015212954.1|850401_852930_+|Eco57I-restriction-modification-methylase-domain-containing-protein
MAINNSRSLSLVNQDESICENLLTQVNSIHLTANNQLTQSHKIEMGQFLTPDAIARFMANMFDFELTEISLLDAGAGTGSLLTAVVFKLCQRLKRPKYLHITAYEIDPFLIDFLEKTLKCCENACYQLGIKFTYTIHQSDFIESVVNLLQYPLLADSITTKFTHAILNPPYYKINSQSKYRLLLRSIGLETTNIYTGFIFAVIKLLKLNGQLVAITPRSFCNGSYFREFRQFFLENMALEKIHLFNSRKEVFSNDKILQETVIVHAYKQSKKPDTILISSSINAEDDLILSHHLCYSDVIDPQDQDKFIHIIPDTLNQQIVEQMKQFFCTLQDLGLNVSTGKVVDFRIKPYLRLNPEKGTVPLIYPTHFDHSYISYPKKTKKCQAIVLAKETNNLLIPNENYVLTKRFSSKEEKKRVVAVVYDATKIDTSSIGFENHLNYFHQQGQGLDLTLAKGLTAYLNSSLVDSFFRLFNGHTQVNATDLRNLKYPTLEQLYLLGKYIGVEFPNQSEIDKLIDRLLLNMTDSSENNPIIIKARIEEAIEILADLGFPKKQLNERSGLTLLALLDLKPYESWISAKAPLLGITPMMEFMEQQYAKKYAPNTRETVRRQTVHQFIDAGLIVVNPDNIERPVNSPKTVYQIEDSALEMLRTFKTDEWDKNLQTYLASIETLKNKYAQARLKARIEVNIPGASISLSPGGQNILIEKIINDFCPRFTPNSNIIYVGDTDEKFAYFEKSALSELGIKIDTHGKMPDIIIHFQAKNWLVLIEAVTSHGPIDAKRKTELESLFKSSQIPLVMVTAFLNRKAMKEYLPEISWETDVWVAEDGTHLIHFNGENLLQIY
>NC_019771.1|WP_015212953.1|847741_850225_-|U32-family-peptidase
MTSTPTLKLPELLAPAGNWECAKAAVENGADAIYFGLDRFNARMRAENFTEADLPELMEFLHLRGVKGYVTLNTLIFPQELTEAQQYLKTIISAGVDAVIVQDIGICRLIRHLSPDFPIHASTQMTITSAAGVEFAKSLGCQLVVLARECSITEINKIQQQIFQKNTSLPLEVFVHGALCVAYSGQCLTSEALGGRSANRGECAQACRMPYDLIADGEVVNLGNRKYLLSPQDLAGLEVLPELVKSGVTCLKIEGRLKAPEYVANVTQVYRKALDKIIKTNIEQKSSVLRKDQYNLEMAFSRGLYTGWFEGINNQELVHANFGKKRGVYLGEVTRISNEQITVKLEAPVKPGDGIVFDCGHPERQEEGGRIYAVVEKGKDVILSFGRNNLNFRRINIGDKVWKTNDPELDKQIRQSYAGENPQFQRPINIEVYGEIGEKLIAIARDEFGNIVQVESEILLVEAHTKPLTTERVKEQFGRLGNTSFYLDNFINNLNGNIMLPVSELNRMRREIVTQLEELRRKPKLWQLNHHGKWQDLITSNFSPIPAFPSLIVLVRNINQLKAVLTADIKTIYCEFENPRNYQEAVKIVRESESEISIFVAPPRITKSGETWILKQVRDSKADGYLIRNYDQLEYFANERCVADFSLNIANPLTADYLQQRFNLERLTASYDLNVNQLEDLITNYPPQNLEVTIHQRIPMFHMEHCVFCAFLSEGTDYTNCGRPCEKLEVKIKDRVGSEHILKADAGCRNTVYNSTAQTGAEYVQRLISLGLQHFRIEFLNETPEQVIKTIHRYNQLLQGEINGSQLWRELKLQNQLGVTRGALSRM
>NC_019771.1|WP_015212952.1|845185_847570_-|dynamin-like-GTPase-family-protein
MSSLAPQCQQLQTQVESILQLLHQETALRSQDITSVQISLDKAISPKFEIVFAGAFSAGKSMLINALLERELLYSAEGHATGTECKIEYAPADSERVVLTFLSEVEVREQAVSLCQQLGFNTVENINQSDVIDLLRQGCTVIIQQEGGESKSERGKQAKALILLLEGYITNRDRINTVNNATYSMEQFNFTNLKEAAGYARRGSNSAVLKRIEYYCHHPLLEDGNVIIDTPGIDAPVEKDAQLTYAKIQHPDTSAVVCVLKPAAAGDLTKEETELLEIMRENTGIRDRVFYIFNRIDETWYNNQLRQRLEDLINGQFRDSSRVYKTSGLLGFYGSQIKQTTISDRFGLDSIFVESVKGLDGREETPQFINEFNRYCANSGKLSPSQFRISVNSFETPNQNYVRILTEQGTPLIKQLIQDSGVEEFRTSITRYLTEEKRPQLFKNLADDLEDICIKLKKHYQSLQRDLDSQPREIESMKEYELQKLNQQLQQVGRDFSQHIHEEVNGLINSNCEQFEADFRQLQSRMIRRLDELLDTFSVADAYRRATLSHPRNATAPLLAILVEAFYYLSNQLEDILIESCQQVIANLFQQLMEKIRKSEYYRQLYRLLGNDGGIESEIKLIEKQVSQALVNAASVECDRFVRESHRFYNEGTFSIYQFRQVLEQTSQGYDAESIIDAEPAIRQLLKLDFEPKVENTIRKSFRQTINQTIKTQLLPMGEKQADDILQQYPHARAYLEKTLEQEAEEKIANNQRLLSQVARKVEEYNTAVTGINSCLQAMQLYEHLLPIIGEEEV
>NC_019771.1|WP_015212951.1|844722_845094_-|KGK-family-protein
MEDNFKLIECNDDDVIECNDLTYKVNKLKQAFEELGSDTNFLISLWEALRRQKIYYLQDRHYNTECFKEGMDVKMLNLGSKSWRKGKLKFKLSVEFYIEEDTEIKEPESPLDDLRRMINDATS
>NC_019771.1|WP_015212950.1|844450_844696_-|HNH-endonuclease
MNKTPRITIPPEVRTYVFQRDKYQCQSCGKTSQETNLSIDHIIPLSRGGKNDISNLQTLCLICNQQKTDKIDNRFHRHFDI
>NC_019771.1|WP_015212949.1|843008_844454_+|glycoside-hydrolase-family-13-protein
MQIQTPDWVKHAVFYQIFPDRFARSKQPRKRLLNEARWEDWEAMPTLQGYKGGDLWGILEQLDYIQSLGINAIYFTPIFQSASNHRYHTHDYYQVDPLLGGNEAFKELLDAAHQRNIKVVLDGVFNHSSRGFFFFHDVLENGPHSPWVNWFKIHGWPLAPYTGELPANYEGWAGIRSLPVFNHDNPEVREYIMEIAEYWIKFGIDGWRLDVPFEIKTPGFWQEFRQRVKAINPDAYIVGEVWGDSREWLDGNQFDGVMNYLFAGPTIAFTAGDRVDLEQVQGRDYQPSPPLFAAEYAAKIKELLAFYPWEIQLTQLNLLASHDTARLITIAGGDIPSAELATLLLLTFPGASSIYYGDEVGLPGALDPDSRRGFPLESNWNLEILDTHKKLISLRHKYQALRIGDYQVLYAQGTLYIFARTLGTEELIIAVNVGTATATGNVDCSSLQTQPEQILFGTGEVEWNSEILDLTIPPRTGCILG
>NC_019771.1|WP_015212948.1|841380_842859_+|site-2-protease-family-protein
MAFWFLLLLGLATYLIVQRSVAHITRTPVWLLWLVLMTPALILSGWTLIYGVKQPPPPGLIIWPLVVSLLLYWFLFLSGRRVPGDAQTQGQMTGSPSANNPTSEASPVRPIEPAEETNLRNCFPWSVYYLQNIEYRPQAVICRGQLRTKANQAYHQIKTNIEEQFGDRFLVIFQEGMNDKPFFVLVPNSQAAKQNTNRASENLTQAAVALSLLLLTLFTTTLIGSQIAGVELTKLKSDLTLLTNGLPYALGLITILGIHELGHYFTARFHKIRSTLPYFIPVPFFLGTFGAFIQMRSPIPHRKALFDVSIAGPIAGFIATLPLLIWGLAHSEVVPLSEKMGLLNPNALNPKYSILLALLSKLALGSELTAQSALNLHPVAVAGFLGLIVTALNLMPVGQLDGGHIVHAMFGQRTAVIIGQIARLLLLMLSFIRREFLLWAILLLFIPLIDEPALNDVTELDNGRDILGLSAIALLLIIILPLPQFLARVLQI
>NC_019771.1|WP_015212947.1|840185_840971_-|MBL-fold-metallo-hydrolase
MSPALQQTSYPIKPPQTVLSGQMPVGEIPANSTETEFTDLGINKIFALPPNRDTLGGTSYLIVRNEGNILIDCPSLEQINQDFWECLGQTAQTEKGVRWLFITHRGAIGKTAEIQQALDCEILIQEQEAYLLPGLNVTTFNQEFTLDATTQAIWTPGHSPGSSCLYYREFGGVLFSGRHLVPNLQGEPVALRTAKTFHWPRQLKSVQALCDRFTPETLQYICPGGNIGFLRGKHFIDQAYQRLEAGGRGQEAGSREQEEER
>NC_019771.1|WP_015212946.1|838921_840157_+|PDZ-domain-containing-protein
MNKKVFRWGFSLLLGFCLIFGAFISPAIALTQEQKLVSEVWRIVNRSYLDETFNHQNWSDVRQQALKKPLLNDQAAYTAIQKMLKSLDDPFTRFLDPEQYRSLQVNTSGELTGVGLQIALNPQTGILEVITPIEGSPAEKAGLRPRDRILKIEGLSTENLTLDEAASRMRGPIGSVVSLLIGREGETDQEIILMRDRIELNPVVADLRLSPQGKPIGYLRLTQFNANAAMELAHAISSLEKKGAVAYILDLRNNPGGLLQAGIEVARQWLDSGTIVYTVNRQGIQGNFEASGQALTPDPLVILVNQGTASASEILAGALQDNGRAQLVGETTFGKGLIQSLFELSDGSGLAVTIAKYETPNHRDINKLGIKPDTVITQTPITRDQIATEADSQYQAAVELLTKNLVVAGSQ
>NC_019771.1|WP_096713183.1|854303_854744_-|GUN4-domain-containing-protein
MNYTRLRDLLAAEKWKEADEETTRVMLAVAKREKEGWLDVNSIDNFPCEYLWTIDQLWVKYSNGKFGFSVQKRIYQGFGGAREYNSQIWEKFGDEVGWRKGVSWLYYKDITFDIKAPEAHLPCGGEGVGEFSRCWYGWGVWRFSRV
>NC_019771.1|WP_015212957.1|856256_858368_-|TIGR00300-family-protein
MVSQIRFLMCAPDHYDVDYVINPWMEGNIHKSSRDRAVEQWNKLYNVIKNHAIVDLVAPEKGWPDMVFSANAGLVLGENVVLSRFLHKERQGEEPHFQHWFEQNGYNVYTLPKDLPFEGAGDALLDREGRWLWAGYGFRSELDSHPYLAKWLDIEVISLRLMDERFYHLDTCFCPLANGYLLYYPGAFDSYSNRVIEMRVAPEKRIAITEADAVNFACNAVNVESIVIMNKASESLKSRLAEVGFQVIETPLTEFLKAGGAAKCLTLRVTEPIGDEIHANASVESRVIRMEGHLLDAGLINRALDLIVEMGGSFQVLKFNLGEQRQSTSAAEVRVSAPSHEVMEEIISQLIDLGAVDLPQDERDSKLEPVIQAGVAPDDFYVSTIYPTEIRVNGEWLKVQNQRMDGAIAISTTANGIVAKCKLLRDLEIGDKVVVDVLGIRTVRKAESREQRNSQEFSFMSSGVSSERRVELVVEQVAWELRKIKDSGGKVVVTAGPVVIHTGGGEHLCRLVREGYVQGLLGGNAIAVHDMEQNILGTSLGVDMKRGVAVRGGHRHHLKVINTVRRFGSIAKAVEAGVVKSGVMYECVKNNIPFSLAGSIRDDGPLPDTQMNLILAQQEYSQIIEGADMILMLSSMLHSIGVGNMTPAGVKMVCVDINPAVVTKLSDRGSIESVGVVTDVGLFLSLLTQQLDKLTSPYIANVG
>NC_019771.1|WP_015212958.1|858627_859770_+|DUF4145-domain-containing-protein
MTEQKYKHTTKTVRCGHCGNKTLMKVISEGEYRKDIYYDSDFEYDCWEIYKIQSLLCPNCEDFNIIKFVENWDSNKIEMCYEPEWVTEIIYLYPLLKEFADISPKAQDIRDTFREARTCFQGELYTSSVVMCRKTMEMLCLYFKIEQPGNLHGKLAKMRDEEIIDNKFYEWANVLKSFGNEAVHSSEKFSKEDTQDILDFTYALVEYCIDFDYKFQQLLERRGKVQPSPDLETTTLTEETIHNLVQKLDDNETSAVRYYAASTLAKINIEIDKVIPVFLSLINSTKFSKDATNYLKSIGSKAIPELINALEKHTSHNVRSAAATILGDIGTNNPDVIESLVKALKDPNDDVQYKAGIALEKLDNIAIDAFVKIYPLPPGS
>NC_019771.1|WP_015212959.1|859776_861222_+|ATP-binding-protein
MKIKFSNLGSIQETELDLRPLTVIIGPNNSGKTYIAYSTYGLWQRACRSISFKQDLNLIKFTHEQEGNWSLIIDDNVLDFFITDAKNAAEQFQGDTLESFFQDSSRKLFSKTSFEIIVSRKEVEDAINHLTHQDPFVLIDGSLLKFSRQGNILYAQVNIEKTNNNRRIINIVNMLENDSKTPPDDLFFFLIKEILFYTEIFPFPVERNAFINTYKMLENSRYKFLKETQRQLFSNSSERRLKLLREQGDIRYPKPVEDFLDFLSEIELQKTPKINPSDKNEFQKLADEIEEQLQNKNKTNLKPTKLGGKEIKVLVKKGLEIDLYNASSSIRQLAPLLLYLRFRASKGDFVVVDEPEMNLHPESQAKLLEALSILVNFGVRILLTTHSPYIMAHLNNLVNGNHENPEILKRQSSSLYLQDERAFLPIDKVSAYEMKDNKLVSLNDPDYGIRWDTLSDVAVDIQQKFFEIYEAGQEKAYETEE
>NC_019771.1|WP_042464545.1|861181_862111_+|hypothetical-protein
MKQDKKKHMKQKNSLAQLLKDKKDKLDWQNFNFLENLLVFCTVPGRTVPKESGVHFRITLDSQNQAICILLEIDRRNDPLIRNQALKRPDYMSLYIDSKSCICTIIEMKGKNHNSLENGIEQILKLKEILQTEISTHLPSKLKVKYQGILLTPYNSQVPDKKIAEEALKGFVILPIKYDHKAELYPYVSKPNKITDRYNHQEITKSNALFIEQILTTIALPKRIPDDYYSSNFLVGNDREGIYINYLLPNDSDYITLLANTKYTEINIEDNEEQEKIKNELDLLNLINRLAIKFSNNQISNYENYQKKI
>NC_019771.1|WP_042464548.1|863127_863322_+|hypothetical-protein
MVCRKHQKTDRNPVVSESFVLEERDIRHRLTISEKLYGREKEVKERLEAFERVSVFLQKYLIII
>NC_019771.1|WP_015212961.1|863396_865055_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MSRTGYVYAQTPDPTSLPSEINPLPSDVLPQPSMPEEQLLPPLELPDQSIPGQDDANAKFQVDRIEVVGSTVFTPEQFAAITNPFVGKELTFVELLQIKDVITKFYTDKGYVTTGALITPQTLEAGTVKIQVIEGSLQEIKITGNRRLQTGYIRDRIQLGAKKPLNVPRLMEKLQLLRLDPRIQNLSAELQMGVIPGTNILQVEVQEADTFSLTTTIDNGRSPSVGSFRRGVDLQEANLLGLGDTLSVGYANTDGSNAINVNYKLPINAHNGTISLGFNQGWNRVIEEPFSVLDIQSNTTSYELSYRQPLIQKPTQELAMGLSFSRQESQTELGLDNIGGFPLSPGADADGKTNISALRFFQDYTQRSTSQVFAARSQFSFGVDWFGANVSDNAPDSRFFAWRGQAQWVRKLASDTLFLVRGDLQLAADSLVPLEQFGLGGQISVRGYRQDTLLTDNGLLFSAELRLPIVRAANIGGVLQLTPFIDVGQGWNTKGDNPSTSTLVGTGLGLLWKQGNNFSARLDWGIPLVSVEGEKSSLQENGLYFSVSYSPF
>NC_019771.1|WP_015212962.1|865340_866066_+|COG4280-domain-containing-protein
MNWTIFLAALGSTSIEFLEVVAIAYAIGSSGYVQEALWGSLVGLIVVLAGAITLGTGLQSLPLQPLQILIGALLLWFGWRWVQKSVRRLATGKRAGWIDDHILEKEGITLDEESLGFSKLNFLIMTKSVALEALEIVVIVTTLGLATSDWYEALTGTALALLLSLVMVISLHQYLVKLPEVLIKLGAGIMLSAMGTFWLGEGIELEFPFDEFSILILITLYSLTAAISVYWLKNQPDSMRN
>NC_019771.1|WP_015212963.1|866155_868687_+|S-layer-family-protein
MRVRPFLLMLTTGLLTPEIMLTSIFLWSCGALAKPTVGIAQVTSDGTTNTIVNPNGNNFNILNGIEKGNNLFHSFSNFSVPTGGSATFDLTNTPNITTIFSRVTGGNISHIDGLIQTLNGNNPASLFLMNPNGIVFGQNASLNIGGSFVGTTANSIKFADGIEFSAVTANTTPLLTMSVPIGLQFGGHPGTISVEGTGHNHKLNGTSPVSGLTSSNGLNLSSEKTLALVGGDLFLNSSFLSAPGGRIELGSITQGNVNINLTSQALTLSYPHDNYSFGNIQMSQRAVASVRGTTPGSIQIQGKQINLLDGSLVVVQNLGSQTAGDITINATESLQVIGMSSDFQSSSGIVNETLQAGAAGNIAITTPKLTIDQGAIVINRTYNSARSGNIVVKANEVSVGGIDPANPSLFPIFGVLMAATYGSGHGGDLWLSTDRLTIFGGGNVGTRSFATGNGGNVNINADTVQVSSLNTLPGSLLISLLSANTFSSGDAGNLQIDTRTLSIQDGGLVSVSTINIGNAGNLTINATNSIDVGGMKDPQNPSYIGAVARLFTIGNRDNRDSTAKAGSVTINTPKLTIHDGGRVFVQNEVLGDAGILKINANTLHLDKNASLLASTKVGEGGNIELHMQDILLMRHGSFINAEAGGSGNGGNIKINAPNIVGLENSDIIANAVNGKGGNIDISTQGIFGLQFRDQLTFESDITASSQFGINGTVDINNFGVDPSSGLVELPENVTDSSQQIATGCSNNTGSSFVATGRGGVPQNPSQEVRSDVYNWLRLGSWSDIRDISAYRGNSASAQIPPSPKTLISATSWHRNPEGKIELVADQSPIQVQQLLTCAAVPKS
>NC_019771.1|WP_015212964.1|868752_871290_+|S-layer-family-protein
MRVRPFPLMLTTGLLTPEIMLTAIFLWSCGALAKPTVGIAQVTSDGTTNTIVNPSGNNFNILNGIEKGNNLFHSFSNFSVPTGGSATFDLTNTPNITTIFSRVTGGNISHIDGLIQTLNGNNPASLFLMNPNGIVFGQNASLNIGGSFVGTTANSIKFSDGVDFSAENASGSPLLTMSIPVGLQMGSNPAAINVNNTGHRLTFLIHPLISSPDRSNNPLGLSVNSDNTLALVGGEIALDGGVLNAPSGHIELGSASNGTVNLNTSVPIWSFDYGNLQQFGNIQLSHQSLTDASGTPAGSIHFQGRNISLNDASAALLVNQGSSNSGDISMNASESLALWGFGTNGFPQSMLRADNFGDGEGGNILVSASQIFLKDGGALHGINFGQGAGSNISVEIGDLLHIVGLSPISGFASSLNTITRGSGKSGDIRVVTNKLQILDGAVIGNSPWGNGAGGNTTINASDFIEVIGENPQNLAASVIVAGTFSQANAGQLTINTPKLRLRDGGGIVASTVNSGNGGDLFINVSDSIEVSGVGSISGLPSRIGARGELLAPPIRQLFGLPDVITGNTGKLILNTSHLQITDGAIVGVDHQGVGDAGKLEINAGSIRLDNGGSLTAATAEGEGGNVFVQANDLIMRHGSSLVTNAGGIGNGGNITINSPIILGLENSDIVANAVQGNGGNINITTQGIFGLKYRNELTSENDITASSQFGVNGTVDINNFGVDPSSGLVELPENVTDSSQQIATGCSHDAGSSFVATGRGGIPQNPTQQARNDVYNWLRLGSWTDIRDISAYRGNIASAQIPPSPKTLISATSWHRNPEGKIELIADKSPIQVQQSFTCAAVSKS

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Crispr_ID: NC_019771_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_6

1703019-1703126

Orphan

A:N

Consensus_repeat	Method
GGGTGCGCGACAGCGCAGGTGGGGTGTATTTCATG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019771_6

>merge|NC_019771|6|1703019-1703126|CRISPRCasFinder
GGGTGCGCGACAGCGCAGGTGGGGTGTATTTCATGTGACAATTTTACCTATAAAGAATCTCGCTTCATTATGAGGGTGCGCGACAGCGCAGGTGGGGTGTATTTCATG

>NC_019771|6|6|1703019-1703126|CRISPRCasFinder
GGGTGCGCGACAGCGCAGGTGGGGTGTATTTCATG	TGACAATTTTACCTATAAAGAATCTCGCTTCATTATGA
GGGTGCGCGACAGCGCAGGTGGGGTGTATTTCATG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015213607.1\|1697686_1698166_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|100048
NC_019771.1\|WP_015213610.1\|1701545_1702874_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|316372
NC_019771.1\|WP_015213604.1\|1695371_1696487_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|372616
NC_019771.1\|WP_015213617.1\|1709675_1711433_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|223929
NC_019771.1\|WP_015213601.1\|1692692_1693412_-\|metallophosphoesterase-family-protein	unknown	unknown	gnl\|CDD\|378975
NC_019771.1\|WP_015213616.1\|1707730_1709368_-\|CTP-synthase	unknown	unknown	gnl\|CDD\|235437
NC_019771.1\|WP_015213602.1\|1693413_1694319_-\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223528
NC_019771.1\|WP_042464721.1\|1703510_1704878_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NC_019771.1\|WP_015213613.1\|1706037_1706199_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213612.1\|1705037_1705925_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NC_019771.1\|WP_015213600.1\|1691665_1692625_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187566
NC_019771.1\|WP_015213620.1\|1714112_1714910_-\|Tab2/Atab2-family-RNA-binding-protein	unknown	unknown	gnl\|CDD\|368938
NC_019771.1\|WP_015213609.1\|1700779_1701343_-\|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl\|CDD\|374761
NC_019771.1\|WP_015213608.1\|1698429_1700643_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226428
NC_019771.1\|WP_015213618.1\|1711525_1713268_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|223929
NC_019771.1\|WP_015213615.1\|1707147_1707576_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213619.1\|1713468_1713969_-\|DUF2085-domain-containing-protein	unknown	unknown	gnl\|CDD\|378277
NC_019771.1\|WP_015213606.1\|1696655_1697690_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NC_019771.1\|WP_015213614.1\|1706221_1707106_+\|ROK-family-protein	unknown	unknown	gnl\|CDD\|224851
NC_019771.1\|WP_015213603.1\|1694315_1695359_-\|ATP-grasp-domain-containing-protein	unknown	unknown	gnl\|CDD\|237195

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015213607.1\|1697686_1698166_-\|N-acetyltransferase	gnl\|CDD\|100048	cd03358, LbH_WxcM_N_like, WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization and transacetylation reactions of keto-hexoses. It contains an N-terminal LbH domain responsible for the transacetylation function and a C-terminal isomerase domain. The LbH domain contains imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X), typical of enzymes with acyltransferase activity.	3.01529e-53
NC_019771.1\|WP_015213610.1\|1701545_1702874_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|316372	pfam13847, Methyltransf_31, Methyltransferase domain. This family appears to have methyltransferase activity.	4.34119e-29
NC_019771.1\|WP_015213604.1\|1695371_1696487_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|372616	pfam13489, Methyltransf_23, Methyltransferase domain. This family appears to be a methyltransferase domain.	4.23617e-18
NC_019771.1\|WP_015213617.1\|1709675_1711433_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|223929	COG0860, AmiC, N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane].	6.18867e-49
NC_019771.1\|WP_015213601.1\|1692692_1693412_-\|metallophosphoesterase-family-protein	gnl\|CDD\|378975	pfam12850, Metallophos_2, Calcineurin-like phosphoesterase superfamily domain. Members of this family are part of the Calcineurin-like phosphoesterase superfamily.	1.002e-21
NC_019771.1\|WP_015213616.1\|1707730_1709368_-\|CTP-synthase	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NC_019771.1\|WP_015213602.1\|1693413_1694319_-\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|223528	COG0451, WcaG, Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	7.6242e-45
NC_019771.1\|WP_042464721.1\|1703510_1704878_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	7.15606e-152
NC_019771.1\|WP_015213612.1\|1705037_1705925_+\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.15464e-79
NC_019771.1\|WP_015213600.1\|1691665_1692625_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187566	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs. This subgroup contains UDP-N-acetylglucosamine 4-epimerase of Pseudomonas aeruginosa, WbpP, an extended SDR, that catalyzes the NAD+ dependent conversion of UDP-GlcNAc and UDPGalNA to UDP-Glc and UDP-Gal. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.58165e-107
NC_019771.1\|WP_015213620.1\|1714112_1714910_-\|Tab2/Atab2-family-RNA-binding-protein	gnl\|CDD\|368938	pfam06485, DUF1092, Protein of unknown function (DUF1092). This family consists of several hypothetical proteins of unknown function all from photosynthetic organisms including plants and cyanobacteria.	1.41321e-140
NC_019771.1\|WP_015213609.1\|1700779_1701343_-\|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl\|CDD\|374761	pfam16734, Pilin_GH, Type IV pilin-like G and H, putative. Pilin_GH is a family from Cyanobacteria. All the proteins are putatively annotated as being general secretion pathway proteins G and H, and are likely to be pilins of the type IV secretory pathway.	1.64257e-28
NC_019771.1\|WP_015213608.1\|1698429_1700643_-\|hypothetical-protein	gnl\|CDD\|226428	COG3914, Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones].	5.72397e-175
NC_019771.1\|WP_015213618.1\|1711525_1713268_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|223929	COG0860, AmiC, N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane].	1.86791e-64
NC_019771.1\|WP_015213619.1\|1713468_1713969_-\|DUF2085-domain-containing-protein	gnl\|CDD\|378277	pfam09858, DUF2085, Predicted membrane protein (DUF2085). This domain, found in various hypothetical prokaryotic proteins, has no known function.	0.00103256
NC_019771.1\|WP_015213606.1\|1696655_1697690_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	9.66022e-55
NC_019771.1\|WP_015213614.1\|1706221_1707106_+\|ROK-family-protein	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	5.57577e-77
NC_019771.1\|WP_015213603.1\|1694315_1695359_-\|ATP-grasp-domain-containing-protein	gnl\|CDD\|237195	PRK12767, PRK12767, carbamoyl phosphate synthase-like protein; Provisional.	3.95299e-73

>NC_019771.1|WP_015213610.1|1701545_1702874_-|class-I-SAM-dependent-methyltransferase
MTNSTSDLWAKIRQQFDSSPYPTIPLDKSPKNDLDLLYIHNLVTPYYLRNQKVIDTKDKVILDAGCGTGYKSLVLAEANPGAKIVGVDISEESVKLARQRLEYHGFDNAEFHVLSIYDLPKLNYQFDYINCDEVLYLFPDIAVALQAMKAVLKPEGIIRSNLHSSLQRVNIFRAQKVFTLMGLMDGNPEDLEIDIVTDIMKALKDNVNLKATTWSPGYEGEDRKETILMNYLFQGDKGYTINDIFSALRVADLEFIKMTNWRQWDLMNLFKEPDDLPAFLGMSLPEISIEDSLHLFELLHPIHRLLNFWCGHPQTAPTIVPFSEWTDSDWENATVCIHPQFQNPKFKTDLIACISIGKTFSVRKYLALTEEFVYIDSSMALCLLPVFDKPLPMMSLVEHWQKFRPLDPLTAEPTDQVKVFQTLQKLLQVLEDFDCIMLERQS
>NC_019771.1|WP_015213609.1|1700779_1701343_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MKTELKAKFIQHLLGKKNNNEGFTLIELLVVIIIIGILSAIALPSFLNQANKARESEGKQYAGSMNRGQQTYYLENQTFATDITLMGLGIATGTTNYTYKLEKSAGGALTAADALVAVLNVAEPVNAVNLRAFIGVTDLIQSGGATTTTAILCQKKDAGAYAASGVSVSVTADTTAPKCAGTFKAIE
>NC_019771.1|WP_015213608.1|1698429_1700643_-|hypothetical-protein
MNNFESLKKQAFTNFYTGEYLQASTLYQELINQQPEVKECHWYLGLSLLLQGKEAEAQTSWMLAVFDGEDAEIEQWTYELVTVLQTEAQRQDELQEYKFAWVIRQHLREIIPGDINNILELIKLSLELENLTEENFQELEIIGILNSDLEEIDRELLFAVLQKTLKLIWSEAWILSFPQACISYLDNLQLTHTVMLTALEAAYTGHRFDLAIKYAELALAINYPNPEVISEVLSHLATFHYELGNFDQGIDISKKICNLAEKTNDFINAYVMLLQGFLRSGGRWYEALPIIEKYESYLHQLIKEQPNLERTRIYRLLNCTYYLPYIRDTPRENRFLHNQVLQVCQNNIQIYAQEQFNRYSQSHFQRIKTPKKQLKIGYLSHCLREHSVGWLARWLYQHHNREEFEIYTYFVTYRSHIHDFLQDWYEQKSDHVRKLGRDGIEIAEQIYQDEIDILVDLDSMTADISCEAMALKPAPIQVTWLGWDGSGIPTIDYYIADNYVLPEYAQEYYREQIWRLPNTYLAVDGFEIGVPTLTRKNLEIPDDAVIYFSAQAGYKRNPDNVRLQMKILKEVPNSYFLIKDIHKEVGVVRQFFEKIAEEEGVSKERLRFLNKVPSSAIHRANLQIADVVLDTYPYNGATTTMETLWVGIPLVTKVGEQFSARNSYSMMVNAGITEGIAWSDEEYIEWGVKLGKETDFRKNIHWKLLKSRQTASLWNGKQFTCDLENAYKKMWQKYIDG
>NC_019771.1|WP_015213607.1|1697686_1698166_-|N-acetyltransferase
MAISQDVKLGNNVTIHHPELVNLYGCKIGDDTKIGAFVEIQKGVIVGNRCKISSHSFICEGVEIEDEVLIGHGVMFINDRYPRSTSNGILKTETDWNVTPVKIKRGASIGSGAVIMCGVRIGEGAMVAAGAVVTNNVPEYAIAMGVPARVTGDVREREL
>NC_019771.1|WP_015213606.1|1696655_1697690_-|Gfo/Idh/MocA-family-oxidoreductase
MIGIGVIGYGYWGPNLVRNFYEIPEAQVITVSDFRLDKLTQVQSRYPTIGITSNYQDLINDDRIEAIAVATPVSSHFDIAMQALRAGKHVLIEKPMTASSEQALQLIAEADKRNLVLMVDHTFVYTGAIRKIREIVETNTLGDTYYYDASRLNLGLFQHDVNVIWDLAVHDLSIMDYVLPPKPCAVSATGISHVSGEPENIAYMTLFFNEQLIAHLHLNWLAPVKVRRTLIGGSQKMIVYDDLEPSEKVKLYDKGITINNNQDNLYKMLIGYRTGDMWCPKLDLTEALNRVVSHFINCIETGDCPVTDGKAGWRVVKILEAATESMKHQGKLVELNWKTSNLSP
>NC_019771.1|WP_015213604.1|1695371_1696487_-|methyltransferase-domain-containing-protein
MQINKLPFFFKSHELPDNGGMPEVLPFNLYFDEELKMFRQQATESLSKILREVYLKGSLAEGSISSESGKIYVEKIINYIFSHFKFNQTSSVLEVGFGSGIILRELKKKGISDLTGIEPGNHSRVEGLEEIELIKGFFPSSRIKRRFDLIFSFGILEHIEDPLDFIGEQSNYLNENGKIIFSVPNCEACLIKGDISIFIHEHYSYFTRESITQLIEKAGLFLEDISLIEGAFIATATKINSNSTKNFIYEQILPNDLFKQINLHILRLKQLFAQYQSFELAIYTPIRAINSLYLTGYNNFRLIDDNSELYDKYLPTLSKPVESFQDILSNPPECILIFSRTFGERIKQKCLNEKSLINTLIITLNDLERHN
>NC_019771.1|WP_015213603.1|1694315_1695359_-|ATP-grasp-domain-containing-protein
MKKNILVTATGGRSVGSGILHALTRNSPDVSERWNVVAADAHPFAWGLYQTNEHTLLPLAKDINYIDSLKTIVNRFKIDAIVPGSEAETTVLSNNTNQFKDCKIVCNRSDLMFYMNDKFLLEKKLKKMGIPYIPTFPLEEYEAALTLFNFPFIVKPTTGTGGSKGLELIATREELNKLIGLINNKSFFCIQPYIGDADNEYTVGILNDKDGNLIDSIVMRRKLIGLSLLTTKQIHDQDYAVSTGYSQGFFVEDKEVSNFCEKIALEFDSRGPLNIQLRKHKGALYIFDFHPRFSGTTPMRADVGFNEVDILLRNHLFGEKFSRLNYRTNVAAIRAFEHVIIPIEKML
>NC_019771.1|WP_015213602.1|1693413_1694319_-|NAD(P)-dependent-oxidoreductase
MTNQRKIFMTGASGLIGSELVKQISTLGYSVNAIYRKNISLQHKNINWIKADLSDIDVESIKPFLNDVDILIHNAASTIIGNTLAEEERIRKTNIDASVKLFQLAGKAGVKKAIFTSSFSFIQKPLPSIIVESSPINAVTPYGMSKHLGENYLKEYAEKYGFKFNIFRVSSPVSFNLALMPTSVVRKWIEESREDKIIKIYGKGTRTQDFVAVTDIAKAFISSIENIDISGTFNIVSGNQLSMLHLAQLITEKFGNTYEFIGNDTNENDRWNISIKKASQLLDYQPEYTSETAIKTLLQNI
>NC_019771.1|WP_015213601.1|1692692_1693412_-|metallophosphoesterase-family-protein
MKIAIISDIHSNKYALEAVLEDISANNINEVIILGDVFGYYPWASETYRLLLSKNNISAIKGNHDEIVLEAYANNLNKHLDYYLIARQNREDLLINEPSALEWLSHLKSSNTLTIDNHKITLCHGTPGNNLNGRYYPDNDMVYDWFPKHNEILLLGHTHYPLIRKIQNGGIIFNPGSVGQPRDGNIASSWGIWNLSNNLWELKRTVYDTKFAIEALIKLNWNKRAILALNKNYSGQLKS
>NC_019771.1|WP_015213600.1|1691665_1692625_-|SDR-family-NAD(P)-dependent-oxidoreductase
MIKNKVLITGGAGLVGSHIADQLVKQGVSEIVILDNFVRGKKANLEWAIANGNINIIEGDIRDQKLLNKIMPGVDVLFHQAAIRITQCAEDPRLALEVLVDGTYNVLESAVKSQVKKVIAASSASVLGMAEEFPTTESHHPYNNRTFYGAAKTFNEGMLRTFNEMYGLDYVALRYFNVYGTRMDIYGVYTEVLVRWMDRIIEGKPPLIFGNGLQTMDFISVEDIARANILAAQSDIRDDVFNIASGIETSLNDLAFSLLKVMKSDLKPEYADERTVNPVQKRLADTSKAERLLGFKAEISLEEGLTRLVDWWKTTKNFL
>NC_019771.1|WP_042464721.1|1703510_1704878_+|thioredoxin-disulfide-reductase
MTNSTVENLVIIGSGPAGYTAAIYAGRANLKPVVFEGFQAGGLPGGQLMTTTEVENFPGFPQGITGPDLMDNMKAQAERWGAELYTEDVISVDLSQRPFIICSQEREVKAHSIVIATGATAKRLGLPSEQQFWSRGISACAICDGATSIFRGAELAVVGAGDSAAEEAIYLTKYGSSVHLLVRSEEMRASKAMQDRVLSNPKIQIHWHTEAVDVFGNDFLSGVKVHNNQTGEVRELPVKGLFYAVGHTPNTGLFKGQLELDEVGYIVTKHGGVETGIDGVFAAGDVQDHEFRQAITAAGTGCMAAMLAERWLSSKGLIHEFHHLPETTDNELKPQPETQTTETEAEFNLQATRHEGGYALRKLFHDSDRLLLVKYISPGCGPCHTLKPILNKVVDEFDGKIYFVEIDIDKDRDIAENAGVTGTPTVQLFKDQELVKEVKGVKQKSEYRQLIESNL
>NC_019771.1|WP_015213612.1|1705037_1705925_+|ABC-transporter-permease
MTITKRRTPSFFNFAKSNLSQRFMLIGLAMTLFFIFLAFFAPVLQAWGWLQNPKEFLSNSIHEAPSLKHWFGTSRLGYDVFSRTIFGVQAALQVVILATALSMVIGVPLGMVSGYLGGKLDKMLLFLMDSIYTLPGLLLSVTLAFVVGRGILNAAIAISIAYIPQYYRVVRNHTVSVKTEVYIEAAQAMGASTWVVLSRYLFFNVIQSVPVLFTLNAADAILVLGGLGFLGLGLPEEVPEWGYDLKQALEALPTGIWWTTLFPGLAMTIMVVGLSLLGEGLNDFVNPRLRRENKQ
>NC_019771.1|WP_015213613.1|1706037_1706199_+|hypothetical-protein
MKDNISLIAAAAGGLMLSVALSGILKGAPVTNWQQVSNSSYPVANVRIISKNH
>NC_019771.1|WP_015213614.1|1706221_1707106_+|ROK-family-protein
MGNQVIGIDLGGTAIKLGRFTEDGNCLQSLIVDTPQPATPEAVLSAIVDAISQIDPDNQTIAIGVGTPGPADATGRIAKVAINLAGWHDVPLADWLEAKTGKPTILANDANCAGLGEAWLGAGCNFPNLILLTLGTGVGGAIILDGKLFVGHQGAAAELGLITLNPDGPMCSSGNQGSLEQHTAISAIRRRTGKEPAELGALAQAGDAQALNFWQEYGKDLGIGLTSLIYVLTPQAVIIGGGVSASFEFFLPSMQAEIEKRVLPTSRLGLQILPAKLGNSAGMVGAAKLALTKI
>NC_019771.1|WP_015213615.1|1707147_1707576_-|hypothetical-protein
MAYWVKIQDQRKEYIINIDHVNTFCYEKNGRITFWLPNSYIPIVINPHSNWEDYQKISKYIEYAQGVESDNAYWVKITYERKDYVINLNYISSFCQEQNGRLTFWLPDINFPIIINPTNNAESYEKVIYFLEKHTGFCFGNG
>NC_019771.1|WP_015213616.1|1707730_1709368_-|CTP-synthase
MTKFIFVTGGVVSSIGKGIVAASLGRLLKSRDYSVSILKLDPYINVDPGTMSPFQHGEVFVTQDGAETDLDLGHYERFTDTSMSRLNSVTTGLIYQSVINKERRGDYNGGTVQVIPHITNEIKDRILRVAKETNPSAVITEIGGTVGDIESLPFLEAIRQLRKEVGRQNVLYMHVTLLPWIASAGEMKTKPTQHSVKELRSIGIQPDILVCRSDRTIPVGLKQKLSEFCDVPVECVITCQDASSIYEVPLILEREGLAQQALDLLQMEQRQPNLTQWETMVERMYSPKHSIEIAIVGKYVRLSDAYLSVVESLRHAAIATHGDLRLRWVNSEALENEPPENYLAGVDGIVVPGGFGSRGIDGKIAAIKYARDRQIPFLGLCLGMQCSVIEWARNVAGLVDANSAEFDPYTSDPVINLLPEQQDVVDLGGTMRLGLYPCRVIPGTLAFDLYQEEVIYERHRHRYEFNNVYRNPLLDSGYVVSGTSPDGRLVEIVELPNHPFFLACQFHPEFQSRPSSPHPLFKGFMQATISRTHPTPTTPKPVQVF
>NC_019771.1|WP_015213617.1|1709675_1711433_+|N-acetylmuramoyl-L-alanine-amidase
MKKVLGLVVFNFLFTSSVALAQSSLLVVFPPTNYQTSTEKIFFIGITPANRQLLINGKPIKRSKAGHFSPSLPLQLGENVFKSSYPNQEREIKITRPSTQPEFPDGLGFAKDSLTPAVDIARLPGELICFGAIAPPQASVSVKVANQIIPLSLQPSQAKLPANSSVLTGRNQPTTSSPSKYQGCTTVAKVADLGQPLFSLTLNGNTATQLGQGKISILTPAQLPVTEVTAPSGVTRTGPSTDYSRLTPLPKGTRAKVTGREGDWLRLDYGAWINSKETKIIPDAVQPQTVIRSVGYRQRAGETEILFPLQVAVPVSIEQSDNRTFSITFHNTTAQTDTIRLDDNPLISRLDWQQVTPNQVKYTLNLKKLQQWGYKLRYDNTTLVLSLRHAPNIHNRKHLPLSGIKIVLDPGHGGKESGSSGMKGYLAKDVNLVLSKLLRDELVQHGAVVVMTREDDRDVSLVERQEIINKEEPALALSIHYNFLPDDGNAEKTRGLVSFWYHSQAHSPAIFLHNYVVNKHREPSIGVFWNNLALTRPSAAPAMLLEFRLMSNADELEEIVNPQQQKKLAKTLADGVTEWFKMVKK
>NC_019771.1|WP_015213618.1|1711525_1713268_+|N-acetylmuramoyl-L-alanine-amidase
MKKLLGLVSFSFIFPSSVAVAQPSLLVVYPPANHQTNTEKIFFIGTAPADGQVLINGKSVNRSKAGHFSPSFPLQLGENIFKVRYQNQEREIKVTRLSTQPQLPDLGFAKDSLTPAVDIARLPGELICFSAVAPPQANVSVKLASQTVNLLPQPSKAELPANSSILTGRNQATISNISKYQGCTTVANPGDLGKPLFSLTLRGQTITQLGSGKVQILAPERLAVAEVIAASGVARTGTSTDYSRLTPLPQGTRATVTGTEGDWLRLDYGAWINSKETKIIPGAVPPQTVIRSVSYRQLAGVTEMRFPLQVPVPVSVEQSDRTFALTLYNTTAQTDTIRLDDDPLISRLDWQQVTPNQIKYTFNLKKLQQWGYNLKYDNTTLVLSLRHAPNIQNRKPLSGIKILLDPGHGGKESGAIGPTGYPEKDVNLVVSKLLRDELVQRGAKVVMTREDDRDVSLVERQEIINKEQPAIALSVHYNSLPDNGDAEKTKGFGTFWYHPQAHNLAVFLHNYAVNKLRKPSYGVFWNNLALTRPSIAPSVLLELGFMSNPYEFEEIVDPQEQKKMAKTLADGVTEWFKTVK
>NC_019771.1|WP_015213619.1|1713468_1713969_-|DUF2085-domain-containing-protein
MQKAILSRSLPINQVSFFADFLLAGMVFGPPIAPFLAASGVFLLPGIADIIYFMGNHVCPQPTLGLELAPPFIMAVCMRCYGTVTGLLITRILYALTNGKGVFWLSQYGWTGAAFASVLMMAYPVELAAQIFGLWDFNNYIVTPFGLITGLAWGLFTMPILHFRRL
>NC_019771.1|WP_015213620.1|1714112_1714910_-|Tab2/Atab2-family-RNA-binding-protein
MSLVWQADFYRSPLRDAAGQILWELLICDATRKFEYVATCPQSQANSNWLTEQFQTAGAEKLPEIIQVFRPQSLGLITAAGNNLSIKVEATRCTLALKQWLQEKQYPIAVDKPPPAPLPENLWGEEWRFATIPAGDIVDEFTERPIPILQIPEFLKPINLGLASTVPVPGVVIYGGRQSMRLARWLQEANPVSLNYIAGAPDGLILEAGLADRWILATFEDEEVAAAAKVYAQRKQVSKGLHFLLIQPDDSGMTYSGFWLLGGED

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Crispr_ID: NC_019771_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_7

1761752-1763483

TypeI-D

A:N

Consensus_repeat	Method
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	CRISPRCasFinder
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	CRT
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	PILER-CR

23 spacers

cas2,cas1,cas4,cas6,csc1gr5,csc2gr7,cas10d,PD-DExK

The CRISPR arrays of NC_019771_7

>merge|NC_019771|7|1761752-1763483|CRISPRCasFinder,CRT,PILER-CR
CATTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTTTCCGTACCCAGGAACAAGAGACAAACCTATCACGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTGCTTATCACTAGCATTCCAGTTGAAATTCCAAAGACGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATAGATTTGGTGAGGAGGGTGGTCGCCTTGCTTGGAGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTCTTTCTTCCACATTTGCTGATGAGTTTAGTTTCAATGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATGGCTCAAATCAGTAGATATCCTCATATTTCTAGAAGAGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATACCCCCCCCGAACAAGTCGGGGGGGCTTCCTCCGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTTGAGCTTCCAGATAAATATGCTGATAAATTACGTGGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTCTCCCCTTAGAGCGTTTATTTCACTCATTATTTCATCGCGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTAATAATCCTGGATAATCCTTTGAGCAAGAGATGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATCTGCGCTTGGTATTTCTTCCACTATTTATGGTGTTGGTTCTGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTTGAAGAATTTGGTAAGTTTCTTCTGGACTATTGCCGTGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATAATACAACCTCTTTGAGTTGAACCAGAGGGAGATAAGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATATAAAATAAAACCTGTAACTAGTTTAGTCGAATGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTATTGCGCCAACACCGTTACTTTGCAAATCAGAGGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTACGATAATACGTATGTCTTTGAAACCATCTGTAGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTTGCGTAGCGTATGGATATGGCTTGTGACAGAGCAAACTTTGGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTTACTAATTTTCTAGCACTCTTAAACAAGTAAGTGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTTAATGGTTTCACCTTCTGCATATCCGGTAAGACCAAAGCCGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTAGCGAAGCATTTTTCGTAAAATCCTAGTCCAGATGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATATTAGGATTGTGAGTTTCTCTCATCATTGTGGAGAGGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTTCCTTTGGCAGCAGTAGCAGCATAAATAATTAATAAAAGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATATGGGATGCTTAAAAAACATCAGCAACTTTCTTTATTCGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTTGACCTAGAATCCCACAGAACAACGAGCATTAAGACATCCGTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT

>NC_019771|7|7|1761752-1763483|CRISPRCasFinder
CATTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TTTCCGTACCCAGGAACAAGAGACAAACCTATCAC
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TGCTTATCACTAGCATTCCAGTTGAAATTCCAAAGAC
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	AGATTTGGTGAGGAGGGTGGTCGCCTTGCTTGGA
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TCTTTCTTCCACATTTGCTGATGAGTTTAGTTTCAAT
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	GGCTCAAATCAGTAGATATCCTCATATTTCTAGAAGA
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	ACCCCCCCCGAACAAGTCGGGGGGGCTTCCTCC
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TTGAGCTTCCAGATAAATATGCTGATAAATTACGTG
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TCTCCCCTTAGAGCGTTTATTTCACTCATTATTTCATCGC
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TAATAATCCTGGATAATCCTTTGAGCAAGAGAT
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	CTGCGCTTGGTATTTCTTCCACTATTTATGGTGTTGGTTCT
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TTGAAGAATTTGGTAAGTTTCTTCTGGACTATTGCCGT
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	AATACAACCTCTTTGAGTTGAACCAGAGGGAGATAA
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	ATAAAATAAAACCTGTAACTAGTTTAGTCGAAT
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TATTGCGCCAACACCGTTACTTTGCAAATCAGAG
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TACGATAATACGTATGTCTTTGAAACCATCTGTA
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TTGCGTAGCGTATGGATATGGCTTGTGACAGAGCAAACTTTG
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TTACTAATTTTCTAGCACTCTTAAACAAGTAAGT
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TTAATGGTTTCACCTTCTGCATATCCGGTAAGACCAAAGCC
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TAGCGAAGCATTTTTCGTAAAATCCTAGTCCAGAT
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	ATTAGGATTGTGAGTTTCTCTCATCATTGTGGAGAG
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TTCCTTTGGCAGCAGTAGCAGCATAAATAATTAATAAAA
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	ATGGGATGCTTAAAAAACATCAGCAACTTTCTTTATTC
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TTGACCTAGAATCCCACAGAACAACGAGCATTAAGACATCC
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT

>NC_019771|7|3|1761752-1763483|CRT
CATTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TTTCCGTACCCAGGAACAAGAGACAAACCTATCAC
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TGCTTATCACTAGCATTCCAGTTGAAATTCCAAAGAC
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	AGATTTGGTGAGGAGGGTGGTCGCCTTGCTTGGA
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TCTTTCTTCCACATTTGCTGATGAGTTTAGTTTCAAT
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	GGCTCAAATCAGTAGATATCCTCATATTTCTAGAAGA
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	ACCCCCCCCGAACAAGTCGGGGGGGCTTCCTCC
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TTGAGCTTCCAGATAAATATGCTGATAAATTACGTG
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TCTCCCCTTAGAGCGTTTATTTCACTCATTATTTCATCGC
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TAATAATCCTGGATAATCCTTTGAGCAAGAGAT
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	CTGCGCTTGGTATTTCTTCCACTATTTATGGTGTTGGTTCT
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TTGAAGAATTTGGTAAGTTTCTTCTGGACTATTGCCGT
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	AATACAACCTCTTTGAGTTGAACCAGAGGGAGATAA
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	ATAAAATAAAACCTGTAACTAGTTTAGTCGAAT
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TATTGCGCCAACACCGTTACTTTGCAAATCAGAG
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TACGATAATACGTATGTCTTTGAAACCATCTGTA
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TTGCGTAGCGTATGGATATGGCTTGTGACAGAGCAAACTTTG
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TTACTAATTTTCTAGCACTCTTAAACAAGTAAGT
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TTAATGGTTTCACCTTCTGCATATCCGGTAAGACCAAAGCC
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TAGCGAAGCATTTTTCGTAAAATCCTAGTCCAGAT
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	ATTAGGATTGTGAGTTTCTCTCATCATTGTGGAGAG
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TTCCTTTGGCAGCAGTAGCAGCATAAATAATTAATAAAA
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	ATGGGATGCTTAAAAAACATCAGCAACTTTCTTTATTC
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT	TTGACCTAGAATCCCACAGAACAACGAGCATTAAGACATCC
GTTTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT

>NC_019771|7|4|1761754-1763483|PILER-CR
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTT	TCCGTACCCAGGAACAAGAGACAAACCTATCACGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTG	CTTATCACTAGCATTCCAGTTGAAATTCCAAAGACGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATAG	ATTTGGTGAGGAGGGTGGTCGCCTTGCTTGGAGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTC	TTTCTTCCACATTTGCTGATGAGTTTAGTTTCAATGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATGG	CTCAAATCAGTAGATATCCTCATATTTCTAGAAGAGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATAC	CCCCCCCGAACAAGTCGGGGGGGCTTCCTCCGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTT	GAGCTTCCAGATAAATATGCTGATAAATTACGTGGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTC	TCCCCTTAGAGCGTTTATTTCACTCATTATTTCATCGCGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTA	ATAATCCTGGATAATCCTTTGAGCAAGAGATGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATCT	GCGCTTGGTATTTCTTCCACTATTTATGGTGTTGGTTCTGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTT	GAAGAATTTGGTAAGTTTCTTCTGGACTATTGCCGTGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATAA	TACAACCTCTTTGAGTTGAACCAGAGGGAGATAAGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATAT	AAAATAAAACCTGTAACTAGTTTAGTCGAATGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTA	TTGCGCCAACACCGTTACTTTGCAAATCAGAGGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTA	CGATAATACGTATGTCTTTGAAACCATCTGTAGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTT	GCGTAGCGTATGGATATGGCTTGTGACAGAGCAAACTTTGGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTT	ACTAATTTTCTAGCACTCTTAAACAAGTAAGTGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTT	AATGGTTTCACCTTCTGCATATCCGGTAAGACCAAAGCCGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTA	GCGAAGCATTTTTCGTAAAATCCTAGTCCAGATGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATAT	TAGGATTGTGAGTTTCTCTCATCATTGTGGAGAGGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTT	CCTTTGGCAGCAGTAGCAGCATAAATAATTAATAAAAGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATAT	GGGATGCTTAAAAAACATCAGCAACTTTCTTTATTCGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAATTT	GACCTAGAATCCCACAGAACAACGAGCATTAAGACATCCGT
TTCAATCCCTAATAGGGAGTAATAGAAATTGCAAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015213651.1\|1752925_1754476_-\|ferredoxin--nitrite-reductase	unknown	unknown	gnl\|CDD\|236572
NC_019771.1\|WP_015213650.1\|1752659_1752884_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213652.1\|1754797_1755094_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_171815782.1\|1755878_1756151_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213668.1\|1772534_1773554_-\|DUF1016-family-protein	PD-DExK	COG4804_PD-DExK_CAS-I:CAS-III	gnl\|CDD\|377634
NC_019771.1\|WP_015213664.1\|1766812_1767232_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213655.1\|1756220_1756412_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213663.1\|1765889_1766708_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl\|CDD\|227838
NC_019771.1\|WP_042465842.1\|1756444_1756885_+\|ubiquinol-cytochrome-c-reductase-iron-sulfur-subunit	unknown	unknown	gnl\|CDD\|223795
NC_019771.1\|WP_015213665.1\|1767232_1767940_-\|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	gnl\|CDD\|187842
NC_019771.1\|WP_052334514.1\|1759170_1759707_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|227751
NC_019771.1\|WP_015213661.1\|1764059_1765061_-\|type-I-D-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|274976
NC_019771.1\|WP_015213667.1\|1769131_1772482_-\|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	cas10d	cd09712_cas10d_CAS-I-D	gnl\|CDD\|274469
NC_019771.1\|WP_015213669.1\|1773566_1773770_-\|DUF433-domain-containing-protein	unknown	unknown	gnl\|CDD\|225291
NC_019771.1\|WP_015213658.1\|1758027_1759077_+\|anthranilate-phosphoribosyltransferase-family-protein	unknown	unknown	gnl\|CDD\|168934
NC_019771.1\|WP_015213666.1\|1767945_1768956_-\|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	gnl\|CDD\|375747
NC_019771.1\|WP_015213657.1\|1757027_1757969_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NC_019771.1\|WP_015213660.1\|1763709_1763982_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_019771.1\|WP_015213662.1\|1765147_1765756_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
NC_019771.1\|WP_015213424.1\|1760170_1761556_-\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015213651.1\|1752925_1754476_-\|ferredoxin--nitrite-reductase	gnl\|CDD\|236572	PRK09566, nirA, ferredoxin-nitrite reductase; Reviewed.	0
NC_019771.1\|WP_015213424.1\|1760170_1761556_-\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	3.83699e-15
NC_019771.1\|WP_015213668.1\|1772534_1773554_-\|DUF1016-family-protein	gnl\|CDD\|377634	pfam06250, DUF1016, Protein of unknown function (DUF1016). Family of uncharacterized proteins found in viruses, archaea and bacteria.	7.93267e-81
NC_019771.1\|WP_015213665.1\|1767232_1767940_-\|type-I-D-CRISPR-associated-protein-Cas5/Csc1	gnl\|CDD\|187842	cd09711, Csc1_I-D, CRISPR/Cas system-associated protein Csc1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas5 ortholog; also known as CasA/Cse1 family.	3.28517e-87
NC_019771.1\|WP_015213660.1\|1763709_1763982_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.85853e-37
NC_019771.1\|WP_052334514.1\|1759170_1759707_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|227751	COG5464, COG5464, Uncharacterized conserved protein [Function unknown].	5.15251e-16
NC_019771.1\|WP_015213661.1\|1764059_1765061_-\|type-I-D-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274976	TIGR04093, hypothetical_protein_L8106_25395, CRISPR-associated endonuclease Cas1, subtype CYANO. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes a clade of Cas1 limited to the CYANO subtype of CRISPR/Cas system and most often the type found there.	8.97399e-147
NC_019771.1\|WP_015213667.1\|1769131_1772482_-\|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	gnl\|CDD\|274469	TIGR03174, cas_Csc3, CRISPR type I-D/CYANO-associated protein Csc3/Cas10d. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family is a CRISPR-associated (Cas) family strictly associated with the Cyano subtype of CRISPR/Cas locus, found in several species of Cyanobacteria and several archaeal species. This family is designated Csc3 for CRISPR/Cas Subtype Cyano protein 3, as it is often the third gene upstream of the core cas genes, cas3-cas4-cas1-cas2.	0
NC_019771.1\|WP_015213669.1\|1773566_1773770_-\|DUF433-domain-containing-protein	gnl\|CDD\|225291	COG2442, COG2442, Uncharacterized conserved protein [Function unknown].	7.27669e-19
NC_019771.1\|WP_015213658.1\|1758027_1759077_+\|anthranilate-phosphoribosyltransferase-family-protein	gnl\|CDD\|168934	PRK07394, PRK07394, hypothetical protein; Provisional.	0
NC_019771.1\|WP_015213666.1\|1767945_1768956_-\|type-I-D-CRISPR-associated-protein-Cas7/Csc2	gnl\|CDD\|375747	pfam18320, Csc2, Csc2 Crispr. The Csc2 Crispr family of proteins forms a core RNA recognition motif-like domain, flanked by three peripheral insertion domains: a lid domain, a Zinc-binding domain and a helical domain. The CRISPR-Cas system is possibly a mechanism of defence against invading pathogens and plasmids that functions analogously to the RNA interference (RNAi) systems in eukaryotes.	5.61385e-173
NC_019771.1\|WP_015213663.1\|1765889_1766708_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	7.30229e-50
NC_019771.1\|WP_015213657.1\|1757027_1757969_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	2.24315e-52
NC_019771.1\|WP_042465842.1\|1756444_1756885_+\|ubiquinol-cytochrome-c-reductase-iron-sulfur-subunit	gnl\|CDD\|223795	COG0723, QcrA, Rieske Fe-S protein [Energy production and conversion].	6.36837e-24
NC_019771.1\|WP_015213662.1\|1765147_1765756_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	8.1498e-54

>NC_019771.1|WP_015213424.1|1760170_1761556_-|IS4-family-transposase
MPNRVKILKEKFSQSVGLPFAELLPESVINESIQELNLKYHQRIFSPVVRIWAFLSQVLDVDKSCQNIVSRVIAWLSTTGAELPSTNTSAYCQARERLPEKLLSKLFSKIGMGLEEKVSQQQLWCGRSVKIIDGSTVSMPDTKSLQEEYPQQKSQKQGCGFPVAKICVLFSLATGAAWEVVIDKLNVHDIKLGRNLYKFLNPGDVLLGDRAFCAYGDIFCLKNQGCDVVCRKNQKRKSHPVEGEITNASDRQVIWYKPKTRPAGMSLEDYRSLPKSLVVREVTYSINIPGFRTENVTLITTLLDTNTYSLEKLAELYGLRWQVELDLRHLKTTLNMDILRCKSPAMIRKEIYVFLLAYNLLRSLMWNAGNLYGVNPLSLSLQRSRQMFINFIPTFLSVQSKYLRHYYLTLLKLLVHQSLPFRPNRIEPRVQKRRPKAYPFMQKPRKLLRRTLIKDNLSVFS
>NC_019771.1|WP_052334514.1|1759170_1759707_-|Rpn-family-recombination-promoting-nuclease/putative-transposase
MVYLQKTDSELVQQTTFTLEETCHRFQVIRLWEQPTETFLQTPGLLPFAVLSNTGNKVNTLQEVATAIDNIPDKQMQSSLAASAFILAGLVLEKEVIQRLLRRDIMRESVTYQLLVEEGREEGRKEGRKEGREEGREEAVQLVAVNMLKEGMSIEFVAKVTGLTFEQVQQLQATNSGD
>NC_019771.1|WP_015213658.1|1758027_1759077_+|anthranilate-phosphoribosyltransferase-family-protein
MSNIFRELLKKVGSGSHTSESLTRAEAAAAMQMMLLGEAKPAQIGAFLIAHRIKRPTGEELAGMLDAFDQLGPKLQPIDAARPVMVLGIPYDGRTRTAPINIITALLLAAAGQPVVMHGGDRLPTKYGLPLIEIWQGLGVDWTTLSLAQTQQVFEQTGIGFVYTPQHFPLTQKLWEYRDQLGKRPPLATMELIWCPYAGDAHIIAGFVHPPTEAMFQVALGLRGTRKYTFVKGLEGSCDLPRDRTAIIGLSSTNSQELERLQLAPRDYGFTTKNVPLATTEELITDFKAVLAGKPGELMQTALWNGGFYLCLSGICPDMTSGIAKAEELFISGAVANQLLLLPLSNQKV
>NC_019771.1|WP_015213657.1|1757027_1757969_+|LysR-family-transcriptional-regulator
MRLEQLQAFLAIAQTGSFQQAAKKCGVTQSTISRQIQALEADLGVELFHRTTHAKLTLGGERLLPRVRKICQEWETATAELADLVAGKQPELCIAAIHSVCASYLPPVLQKFCHSYPDVQLRVTSLGSDRSLKVLKDGLVDLAIVMHNRFLIAGREMAVEVLYEEPIEVLTAANHPLAKYESIPWSDLIRYPQVVFKDGYGMQRLIQDRFERMEATLIAALEVNTLDAFRGVVRQGELIALLPQSALMEAKFDPSLAVRPLACNTNLADNSSLTRRVVMVTTHDRLQIPPIQHFWQLVKDNIPPQFDQKFSAS
>NC_019771.1|WP_042465842.1|1756444_1756885_+|ubiquinol-cytochrome-c-reductase-iron-sulfur-subunit
MKRREFLNWVGLGLLASSLPVAIAACSTETTTSASSKSGAATQKWQKVGTVAELDKTGQLLLADSPVGAVLVVGTSKAAKDLSAVNPTCTHKGCTVVWKTNKNQFVCPCHDAEFARDGKVQEGPAEKPLKTYIAKIESDSVFVKIA
>NC_019771.1|WP_015213655.1|1756220_1756412_+|hypothetical-protein
MEISSLVGTRESQVCVWELISDKILYQSTEVSPCLMSADGRVLIQCTKEFEINDIIQIISNNE
>NC_019771.1|WP_171815782.1|1755878_1756151_+|hypothetical-protein
MGEHKRDFELAQAHEFGLGKNGKVYVVNFQDFVWSLDIETQEHIRNHANNIMSVILPNSRCPAVCYTQSLVVVGNSVGYKGEFEVWNYET
>NC_019771.1|WP_015213652.1|1754797_1755094_+|hypothetical-protein
MLLIENQQESMKTRIEKIVNILMEERHLFKDELNAEEMVQHLCNTFHKNVSFEEFKSMEQEDLKNRCSGILSVQMLSGLLDDLTPEQIAIFDEAVKRK
>NC_019771.1|WP_015213651.1|1752925_1754476_-|ferredoxin--nitrite-reductase
MTETATTTEKLNKFEKLKAKKDGLAVKGEIDEFAKIGWEAMDEEDLNHRLKWLGVFFRPVTPGKFMMRMRIPNGILNSSQLSVLAEVIQRYGDDGSADITTRQNIQLRGIKIEDIPEIFNKFHTVGLTTIQSGMDNIRNITGDSVAGLDANEFYDTRELVQQIQDMLTNNGEGNPEFSNLPRKFNIAITGGRDNSVHAEINDLAFVPAFKDGFGFNVLVGGFFSGKRCEAAIPLNVWVKPDEVVSLCRAIVEIFRDHGLRANRQKARLMWLIDEWGLEKLRTEVEKRWGKTFKTAAPKDEIDWEKRDHIGIYPQKQPGLNYVGLNIPVGRLYADDMFELARLAEVYGSGEIRFTVEQNAIIPNITDSALTAFLTEPLLNKFGVNPGLLMRSLVSCTGAQFCNFALIETKNRALAMIKVLESELILSRPVRIHWTGCPNSCGQPQVADIGLMGTKVRKNGKTLEGVDIYMGGTVGKDAHLGTCVQKSIPCEDLEPVLKEILIQNFGAKLREAALISH
>NC_019771.1|WP_015213650.1|1752659_1752884_-|hypothetical-protein
MSNISRRKFIITSSVAAATSILVHGCSSSNSKSATTDSAAFSTAKLANNSTVTNAPKVETTTAKLEFIALKDNL
>NC_019771.1|WP_015213660.1|1763709_1763982_-|CRISPR-associated-endonuclease-Cas2
MNVVVSYDISEDKRRTKIHNILKSYGQWVQYSIFECQLTDTQYAKLRSRLNKLIKPNTDSIRFYFLCACCFGKVERIGGEQPLDTTIFFA
>NC_019771.1|WP_015213661.1|1764059_1765061_-|type-I-D-CRISPR-associated-endonuclease-Cas1
MGTLYVTQNDSFVGKVDERIHVKFEKKVLQDIPFIHLKDVVVLGRATVSPAVVFELMSRHIPLSFIDERGHYLGRLEPEMTGNIFVRKAQWQAAGESLQAVHVVQGFIRGKLKNYRQVLMRCQRESDVDLSKYITRIEQTISPIDSTHNIKSLRGLEGAGSAAYFGCFNQLIRNPDFTFTKRVRRPATDPVNSLLSFGYSLLRHDVQGAVNIVGFDPYLGYLHCDRYNRPSLPLDLMEEFRPLVVDAVVLSILNKQLLTPADFISEPLSGAVSLTPKGRKIFLTKYEKKKQSEFKHPVMGRKCTYREAFEWQARLLAKYLMGETDKYPPLVLK
>NC_019771.1|WP_015213662.1|1765147_1765756_-|CRISPR-associated-protein-Cas4
MLVQNINSDDYVNIASLNQYSYCPHRCWRIHCAGEFIDNQYTIEGTSLHERVHTVGEVNRDETWQIRAIYLKSDQYQIVGKSDLIEFENGEFYPIEYKRGQKGEWDNDELQVCAQALCLEEMTGKNINSGYIYYAQSHQRQLVEITPELRASTIATIEAVQMLLFTGAMPKPVKTKRCDSCSLYSRCLPQAVEKVGRYKEVN
>NC_019771.1|WP_015213663.1|1765889_1766708_-|CRISPR-associated-endoribonuclease-Cas6
MPHSLILNLTPQSPIYPNFLTGRHYHALFLNLVSSVDRKLGDYLHESNADKAFTLSPLQVQSRHKIQSHTLQYAHQNPISAGTSCWWRVSLLDDNLFSQLTPLWLNLNPEQPWHLGSANLYITSIQGTPQSTQPWANVCSYKQIYEQASEQERTFNFIFSTPVAFRQGGFDNLLPTRESVFNSLLNRWNKYSGIELNNIPLEAIYPSGFNINTEVISNYENKFIGCLGEISYRILGNVETIGIKQVNALANFALYAGIGRKTTMGMGMVRRR
>NC_019771.1|WP_015213664.1|1766812_1767232_+|hypothetical-protein
MNVDNYREATALTKKLEASLPIKAKAAKELLKMLKTRGDIINPDKEFEIDWVAYSGDEGGIMCRLVSKNDNPEDEDKAQYVVSITHLKIDPDHPHAEEIVTYQRERNRQLMLQNRSSLITELMPSRPSKPKKSSKGFGK
>NC_019771.1|WP_015213665.1|1767232_1767940_-|type-I-D-CRISPR-associated-protein-Cas5/Csc1
MTIIYCCQLELHDSLYFATREIGRLYETEPIIHNYALCYALGLVDSPFYSTTVAEEDSYRYFCPEQVPKYEQHLTPLNEQGIYITPARSLNHTAILNTWKYANNNYHVEMEKTQKNIPSFGRAKEIAPESKFEFFLIAQKEIKLPKWIRLGKWMSKAEVRVEKLPQPKTKTDVFTCTHPLNPLDVMFTNQVISYDVVNMPPVSLIQNVQMRGEYYYFDDVKNVKLPKQMQYRFRS
>NC_019771.1|WP_015213666.1|1767945_1768956_-|type-I-D-CRISPR-associated-protein-Cas7/Csc2
MALLKTVDAKLFQSEIPYKPMGKYAHFLTIRVTESYPLFQTDSELNKARVRAGVKDKNTISRLSMFKRKQSTPERLVGRELLRKYEYMTAEECEYNVSFAMDNPDCIIYGFAIGDSGSEKSKVVVDTAFSITSFDESHETFTLNAPFENGTMASKGEGGSKAGEVTSRINQQDHIRPQVFFPSIVTLKDPTEANFLYVFNNILRTRHYGAQTTRTGRVRNELIGVVFADGEITSNLRWTQAIYDQMKANNTLKSPDPLDEDDVMAAAKTAIENLMADEFIVHNDFIGDAFVPLISEVKNLTNNEAGIKSILQKADTEAKEYANKHISKKKTAAKTK
>NC_019771.1|WP_015213667.1|1769131_1772482_-|type-I-D-CRISPR-associated-protein-Cas10d/Csc3
MAKKSKDTNKHQQLSLLEIEKNSNSATSDDDWLSGDFGFDGDNDRTIETKGQLLTLKLLREAIQAENPHDQVMADFSEYVLPNLLKIAIGVTAKGGKFFDEIDEKREAEGKTKVRRDNAADQSLNTHLLNGLFPANLIEQRLEKLDTTVKRLVKDKERRLVIAGFILHDFEKFPDAPEDCRKLPLDEHRKIIDEKIKQLGLDKLINPHNPEDYQSYIDDLLCMAYNAQRRWDTNWNFSEFGLNPVLKDRTIRSLSDLTCLADSLASIIKHPQDAENTRLNEILHSLSDGKLKFTYHHIAENRGVLTNVVNNAVIEAHTNLNAAENTYYQPLLYLPTGVIYLALRDAPRISPEILPDLVVNKIKSLCAGQLKLRQTGFGRDGKGMKYAEYYNLFFESPGLMQVALDATLRILNTGKTSVGKSRSENLVKFQKQNVLSADYDFKFDDDIRIDQIAEFGDLITRKIWEETVDRIETARKKDKKLPEVPNFDLTHKVAEFWNLTEYLPQVREIQRINESLKEQKLKGNTGGVPYEWYYLAAKYLEKHPGIEDVRENCQQVIYYLTDLISPILAQYQLPDGWDDLRLWVSRVVMLPNTNKQTSLTTEVDNFINELSNYNAAKKPGRGKQLICSISHSAYTVTEQMESAVLFTPQVYTNKQMLGGSNAKRNISSIAGVEMMLRQILMNQTQAVGKRFEDGKYRYLYFYPTYYFTPETNKFLQKAYMNIAQTRFDTSIRNHFISKDLQVDLGKENYQSVDSFLIDENLDGEKDRTFKLSYPEDQPLTFYFMALPPGRDSSDTESWVMPSWLAFAFPMILDVKTVVSESPIPPFNDGAEFEETVFLDSAPHAFRTLVKRDRFRLDYILEGWEEYGIQYPAPLNVLTAAYAIHLDVNARQGKTGYDANWGKFTELAKDFETSPLHVFAYLNKWVRNQGIETARIEKIKLYTYHFYPCFDPYTKFDSTKEKLIVGEVSTLNHPKKLTELYRRFYRANKRFNPKANAVLKPIDIAAETILKADSSVFDGETLISAVAAEVFKLMDRVHSSTAEGRWIMSKREEERQAVLEFANYFVVEVFEGCFKSDRARLAGRQLNLIRDTCEFLYRLEDDKENAEKSKSEIDENE
>NC_019771.1|WP_015213668.1|1772534_1773554_-|DUF1016-family-protein
MNNPIADDYRHLLMEVKQRIRSAQYEALKAVNREMINLYWDIGQMIVIKQQDSIWGKSVVEKLAKDLQAEFPGISGFSAANLWRMRLFYESYAKNEKLAPMVREIGWTHNIVILEKSKDDLEREFYIRMTRKFGWTKNVLIHQIENKTYEKTLLNQTNFDQNISSEIRNQLKLAVKDEYTFDFLELADEHSERQLEQAILGKVKPFLQEMGGIFAFIDSQYRLEVDDEEYFIDILLYHRRLKCLVAIELKIGKFLPEYVGKMQFYLSVLDDTVKLPDENPSIGIILCKSKQRTIVEYALKDSNKPIGVATYQIVSKLPQELKNQLPDPEQVAKLLEGFE
>NC_019771.1|WP_015213669.1|1773566_1773770_-|DUF433-domain-containing-protein
MTEQKLLEKITFDTQIFDGKPIVCGRRLAIEHILGMLAAGDTIETLLEAYPWLEREDVQACLVYKNN

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Crispr_ID: NC_019771_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_8

1822408-1822484

Orphan

A:N

Consensus_repeat	Method
ATCCTGGACATCCTGATTCAGACAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019771_8

>merge|NC_019771|8|1822408-1822484|CRISPRCasFinder
ATCCTGGACATCCTGATTCAGACAACCACAACACAAAAAATCATCCAATCACATCCTGGACATCCTGATTCAGACAA

>NC_019771|8|8|1822408-1822484|CRISPRCasFinder
ATCCTGGACATCCTGATTCAGACAA	CCACAACACAAAAAATCATCCAATCAC
ATCCTGGACATCCTGATTCAGACAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015213714.1\|1817874_1818753_-\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|376615
NC_019771.1\|WP_015213728.1\|1832407_1833517_+\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597
NC_019771.1\|WP_015213729.1\|1833765_1835526_-\|alkaline-phosphatase	unknown	unknown	gnl\|CDD\|224699
NC_019771.1\|WP_015213719.1\|1821601_1821985_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|350305
NC_019771.1\|WP_015213726.1\|1828866_1829940_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NC_019771.1\|WP_015213723.1\|1825450_1825774_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369367
NC_019771.1\|WP_015213713.1\|1816874_1817687_-\|precorrin-4-C(11)-methyltransferase	unknown	unknown	gnl\|CDD\|225430
NC_019771.1\|WP_150111079.1\|1821309_1821414_+\|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|143393
NC_019771.1\|WP_081593739.1\|1819643_1820189_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226127
NC_019771.1\|WP_015213725.1\|1827300_1828737_-\|TldD/PmbA-family-protein	unknown	unknown	gnl\|CDD\|223389
NC_019771.1\|WP_015213722.1\|1825021_1825399_+\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|132914
NC_019771.1\|WP_150110996.1\|1831630_1831798_+\|Uma2-family-endonuclease	unknown	unknown	unknown
NC_019771.1\|WP_015213720.1\|1821981_1822179_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213721.1\|1822614_1824966_+\|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl\|CDD\|369272
NC_019771.1\|WP_015213718.1\|1820855_1821116_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213717.1\|1820463_1820856_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|350219
NC_019771.1\|WP_015213724.1\|1825859_1827209_-\|TldD/PmbA-family-protein	unknown	unknown	gnl\|CDD\|223389
NC_019771.1\|WP_015213715.1\|1819056_1819611_+\|pantetheine-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|234674
NC_019771.1\|WP_015213712.1\|1816417_1816771_-\|macrophage-migration-inhibitory-factor-family-protein	unknown	unknown	gnl\|CDD\|366507
NC_019771.1\|WP_015213727.1\|1830001_1831483_-\|cysteine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234705

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015213714.1\|1817874_1818753_-\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|376615	pfam01790, LGT, Prolipoprotein diacylglyceryl transferase.	4.60566e-99
NC_019771.1\|WP_015213728.1\|1832407_1833517_+\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	1.34986e-119
NC_019771.1\|WP_015213729.1\|1833765_1835526_-\|alkaline-phosphatase	gnl\|CDD\|224699	COG1785, PhoA, Alkaline phosphatase [Inorganic ion transport and metabolism].	1.29727e-69
NC_019771.1\|WP_015213719.1\|1821601_1821985_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|350305	cd18738, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily. The PIN_VapC4-5_FitB-like subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This subfamily belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	7.35302e-40
NC_019771.1\|WP_015213726.1\|1828866_1829940_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	6.38252e-43
NC_019771.1\|WP_015213723.1\|1825450_1825774_+\|hypothetical-protein	gnl\|CDD\|369367	pfam07444, Ycf66_N, Ycf66 protein N-terminus. This family represents the N-terminus (approximately 80 residues) of Ycf66, a protein that seems to be restricted to eukaryotes that contain chloroplasts and to cyanobacteria.	0.00387209
NC_019771.1\|WP_015213713.1\|1816874_1817687_-\|precorrin-4-C(11)-methyltransferase	gnl\|CDD\|225430	COG2875, CobM, Precorrin-4 methylase [Coenzyme metabolism].	1.23279e-124
NC_019771.1\|WP_081593739.1\|1819643_1820189_+\|hypothetical-protein	gnl\|CDD\|226127	COG3599, DivIVA, Cell division initiation protein [Cell division and chromosome partitioning].	1.32928e-08
NC_019771.1\|WP_015213722.1\|1825021_1825399_+\|STAS-domain-containing-protein	gnl\|CDD\|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	1.64178e-21
NC_019771.1\|WP_150111079.1\|1821309_1821414_+\|nucleotidyltransferase-domain-containing-protein	gnl\|CDD\|143393	cd05403, NT_KNTase_like, Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins. S. aureus KNTase is a plasmid encoded enzyme which confers resistance to a wide range of aminoglycoside antibiotics which have a 4'- or 4''-hydroxyl group in the equatorial position, such as kanamycin A. This enzyme transfers a nucleoside monophosphate group from a nucleotide (ATP,GTP, or UTP) to the 4'-hydroxyl group of kanamycin A. This enzyme is a homodimer, having two NT active sites. The nucleotide and antibiotic binding sites of each active site include residues from each monomer. Included in this subgroup is Escherichia coli AadA5 which confers resistance to the antibiotic spectinomycin and is a putative aminoglycoside-3'-adenylyltransferase. It is part of the aadA5 cassette of a class 1 integron. This subgroup also includes Haemophilus influenzae HI0073 which forms a 2:2 heterotetramer with an unrelated protein HI0074. Structurally HI0074 is related to the substrate-binding domain of S. aureus KNTase. The genes encoding HI0073 and HI0074 form an operon. Little is known about the substrate specificity or function of two-component NTs. The characterized members of this subgroup may not be representive of the function of this subgroup. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, co-ordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are conserved in this subgroup.	0.00530235
NC_019771.1\|WP_015213721.1\|1822614_1824966_+\|SpoIIE-family-protein-phosphatase	gnl\|CDD\|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	3.393e-55
NC_019771.1\|WP_015213725.1\|1827300_1828737_-\|TldD/PmbA-family-protein	gnl\|CDD\|223389	COG0312, TldD, Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only].	4.14894e-102
NC_019771.1\|WP_015213717.1\|1820463_1820856_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|350219	cd09871, PIN_MtVapC28-VapC30-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC28 and 30 and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC28 and VapC30 toxins. M. tuberculosis VapC28 and VapC30 both cleave tRNA25Ser-TGA and tRNA28Ser-CGA. It belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is a PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.19873e-62
NC_019771.1\|WP_015213724.1\|1825859_1827209_-\|TldD/PmbA-family-protein	gnl\|CDD\|223389	COG0312, TldD, Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only].	2.80556e-51
NC_019771.1\|WP_015213715.1\|1819056_1819611_+\|pantetheine-phosphate-adenylyltransferase	gnl\|CDD\|234674	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional.	1.90888e-99
NC_019771.1\|WP_015213712.1\|1816417_1816771_-\|macrophage-migration-inhibitory-factor-family-protein	gnl\|CDD\|366507	pfam01187, MIF, Macrophage migration inhibitory factor (MIF).	2.23989e-24
NC_019771.1\|WP_015213727.1\|1830001_1831483_-\|cysteine--tRNA-ligase	gnl\|CDD\|234705	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated.	0

>NC_019771.1|WP_015213720.1|1821981_1822179_-|hypothetical-protein
MPLIKIPRHYLVSQDEDSITVNVPQSMLLNWKKDYEKIIQAKGILKHKKAAILAHLDTLRQEWEE
>NC_019771.1|WP_015213719.1|1821601_1821985_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MRYLYDTNIFIYYLADDITVNSWFTEEFLNLHEILISPIIRIELLSFAGLSKEEEQSIEDLLSQFNSVPLLREIENQTIQLKRQYKIKLPDAIIAATAINQAAFLVTRNISDFKGVTGLKIENPFVN
>NC_019771.1|WP_150111079.1|1821309_1821414_+|nucleotidyltransferase-domain-containing-protein
MKITRIRGTAQPDSDIDILIVSKDVLTISKKVRN
>NC_019771.1|WP_015213718.1|1820855_1821116_-|hypothetical-protein
MQQINFDARVDENGFLYLKMPSNFAGMEITGKLLYQAHPISLPNRKENKIDINLVRSICHQIRSLPMLDSRTPDEIIGYNEFGIPE
>NC_019771.1|WP_015213717.1|1820463_1820856_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MVIDTSAIMAIIYAEPEELIFMQIINESEDCLLSSPGYVEASIVLGTKHGQQGVENLNLLIAALSITIVPFTVEQAQLASAALLKFGKGRHPAKLNMGDCFSYALAKSTNQPLLFKGNDFIHTDIDQVNY
>NC_019771.1|WP_081593739.1|1819643_1820189_+|hypothetical-protein
MVLSGLQIPLVRRTLVDEDKLLEQLDFVRVSLPSVFQEAAELLQQKEEIMLEAEEYGQQVVESAQAKRAQILAESDIIRQAEREAEQLRRKVQQECDAMMQDTLAEIEQKRRACMQELEEMRQSAIAQAQEIEDGADQYADNVLENIEQDLQEMLRIITNGRLQLRGDIPKQRNSPNSKKR
>NC_019771.1|WP_015213715.1|1819056_1819611_+|pantetheine-phosphate-adenylyltransferase
MIAIYPGSFDPITLGHLDLIQRGSRLFDGVIVAVLRNPNKMPLFTVQQRIDQIRLTTKHLPNVEVDSFDGLTVNYAQMRQAQVLLRGLRAVSDFEIELQMAHTNKTLSTQIETVFLATSNEYSFLSSSVVKEIAKFGGSVDHLVPPHIALDIYQCYNQNSPALNLITTETTLHLQSSSLLDQQV
>NC_019771.1|WP_015213714.1|1817874_1818753_-|prolipoprotein-diacylglyceryl-transferase
MELDFFALPLGFQFTSPGPILLKLGPIVIRWYGLLIASSVLIGVSLSQYLAKRRHVDPELISDLSIWLVIGAIPAARLYYVLFQWSEYSQHPERIIAIWQGGIAIHGAIIGGVTAALIFAKLKKISFWQLTDLVAPSLILGQAIGRWGNFFNSEAFGDPTNLPWKLYIPPERRPHSLANFEYFHPTFLYESLWDLMVFALLLTLFFRALSSKPRLKVGTLFLVYWVAYSLGRLWIEGLRTDSLMLGSLRIAQIVSLTGMFFGLAGLAWLYFLKRPLPDVVSPSKGDVEKGLG
>NC_019771.1|WP_015213713.1|1816874_1817687_-|precorrin-4-C(11)-methyltransferase
MSEYTNNLSSASVMQHPLASAVYIVGAGPGDPDLLTVKAQKLLAAADVILFADSLIPEQILDICRQDAQIIRTANKTLEEILPIMIEGVRSHKSVVRLHSGDPSLYSAIHEQMQLLTEANIPFEVIPGISAFQAAAAKLKVELTVPGLVQTIILTRISGRTEVPATEELATLASHQASLCLYLSARHVADAQTKLLEHYPAQTQVAICFRVGWPDEKIMVVPLDEMATCTHKQQLLRTTLYIISPALLPVTGRSRLYHPEHNHLFRSSHQ
>NC_019771.1|WP_015213712.1|1816417_1816771_-|macrophage-migration-inhibitory-factor-family-protein
MPLIKVQTSVSAPEKSEIESMLKGLSAKLAKHTGKPESYVMTSFEPEIPMTFAGTTDPVCYIEIKSVGTMKSEQTSAMSQDFCQQINSFLGVPKNRIYIEFADAKGSMWGWNSTTFG
>NC_019771.1|WP_015213721.1|1822614_1824966_+|SpoIIE-family-protein-phosphatase
MKKLSIFRFKSITHRLIFSCVVAAIAIYGVSYWQARKLLQKSVDGWLIDLAQSRIDTVANEMEGKLQAIERSMLLSIYGIEKSAQNSNAVNQTELLPILTTLVEKQPQIQAVALINGSNISETGWYYDRQGKYTKLNLEASKIWLNRCQIKGNTPATLPFWTQPYPLNHPSAITYCFPVSVNSNPETITWLVMEVNLDWVSPNMAKKLAQNNQSHGLELGNYFVFSPSNAQWIVKPENSQLLHLSLSGQNHNLNNQQPSTGLINARNNSQGILVTTKVNSTNWIVGITFPSAKLEQFQQQYLWLVIVSMSKDMLLICVVIAFISQLTTRPLRELNTSTQEMAQGNLDTKLPAVTSDDEVGRLTQSFRQMRDSLQLYISNLQETTAAKQKLESELSIAAQIQRTMVPRTTVDSSPNSPYQISALLKPARIVGGDLYDFFLLGSDRLCIIIGDVADKGFPAALLMARTVTLIRTLTKPFHTPSEILQTVNQQLCAENEECLFVTVFCGVIDLRSGKFIYASGGHDAPILIHDQQVKYLDLETSPPLGLYEDSLFEESEYVLAANDLLLLYTDGITEAMNSQGEIFSEARLIEMMTSYPPSNPARAVRTIVHFCQEFVGEAPQSDDITLLAVQYLPSSPFSQAVNVMEWNLTLNSELTELETVKQSLGKILQAASLTVELIEDAQLIVEEVLVNIIQYGYENHSSAYIDLRIEINDQQLIMTFKDSGKAFNPLTEIASPDMMMDDEERSLGGFGFFLVQELAEQVDYVYINGQNVLTVRQAIAKVA
>NC_019771.1|WP_015213722.1|1825021_1825399_+|STAS-domain-containing-protein
MSLQIYVETTNPTTLCLALDGQLDTLTATDLDKSIHNSLTPNIQTLILDLQKLSFISSAGLRILAKARKTMKSREGKVYFTHPTPQVKKVFDIVKAVPLSEVFSNTQELDAYLEAMQAEVDGESD
>NC_019771.1|WP_015213723.1|1825450_1825774_+|hypothetical-protein
MFTLAQVSFGRNSTSLIGIIYLLFAVAYFLIMLFLLFLRRSKSRNLILVFDIIQLIFVPLIMLFCGFILLFQGWRLDPILQFVQFLLFILITYLLIKDIVFSTIDRK
>NC_019771.1|WP_015213724.1|1825859_1827209_-|TldD/PmbA-family-protein
MKFAELSVLESNFNQLVEGLLIKKMATEHFTVRLSSEISQFTRFNHAKVRQTGLVVDGWIKLTLMANQRSSFRQFPFTGDWEIDWQLGYSALQELRDELTLLPIDPYLVLPTGNNTSREVNSGKLLTPETLVSHILEAVTDLDFTGIYAGGFVIRAYGDSGGQKHWFVTDSFTLDYSLFNELGQAVKGTFAGSNWDESNYIAKINDAKEQLVMLSRPAKELPKGQYKTYFAPSAVAELLSMLSWGAISEADIQQGNSALAVLSRQEKQLSRKFTLKENFQQGLVPRFNDLGEMAAPELDLVEKGILINTLVNSRTAKEYNKPANGANSSETLRAPEISPGNLAFADILSSLDTGLYVSNLHYLNWSDRPTGRITGMTRYACFWVENGEIVAPIENLRFDESLYRFWGEENLVDLTDFQEFIPDVGTYESRQLGGSLVPGMLVKDFTYTL
>NC_019771.1|WP_015213725.1|1827300_1828737_-|TldD/PmbA-family-protein
MWSELTKAIAHLNIPADWIGIRAVKETASIHFVRDGLPKSNGKYLTTGAMLEVMVNGCLGYAATNSLSLPSLQTASQIAYKQALAASEWWIYKFNENTRPKVVGEYNSPFVEPFDAISPGEINDLLIRVCQKLKINDKIVQTTARINTSEKETWFVSSNGSEVYQKILSLGNHFGAIAQDGAIVQPRTNNGTEANSYQGGWELLKQDHLWSQVEKVSEQALELLTAPECPDTRTNLVLAPDQMMLQIHESVGHPLEIDRILGDERNYAGGSFVTKEDFGQLKYGSSLMNITFDPTVKGEFASYGFDDTGAVATKEYVIKEGILQRGLGSLESQSRADLPGVACARASSWNRPAIDRMANLNLEPGNATFDEMISGIEQGVYMESNRSWSIDDRRYKFQFGCEYAKLIENGKLTKTIRNPNYRATTPEFWHSLIQVGNADNWQMYGTPFCGKGEPNQAIWVGHGSPFCVFANVEVFGGG
>NC_019771.1|WP_015213726.1|1828866_1829940_-|AI-2E-family-transporter
MTEKKISLSELLLIVAIGCLVILLWQLQSLLVTLMIAVVLASAIAPIVNAAEKLRIPRWLGVIVVYISLIAGLVGAGLIIGPSVSEQIQRLANKLPIYLENLQITTENIALRMGITQIETIEQFLDIQALTKWVFSSSQQLLVRSFGLTRGILGGVVNLILALVISGYMVAGSSNLVKGLAELFPQPWDQHLAEQVAPISRRMGGYVQGRVLVSAILGVVITLSLSVLGLSEFALALGVIAGFTNLIPFIGPILGAIPALIVAIPEGGLTFLWVLLLFVVIQNIESYVLDPLLVGSSVRVHPLYQLLAVLGGTQVLGIIGAVIVPPWVAGVAVLLENLYLRPKMLAQGKSSVVELDN
>NC_019771.1|WP_015213727.1|1830001_1831483_-|cysteine--tRNA-ligase
MTLSIYNTLSRRQEQFTTVEPGKVKMYYCGVTVYDYCHLGHARACIVWDVVRRYLQFIGYDVRYIQNFTDIDDKILRRAREENSTMEAIADRYIQAYFEDMSRLGIKEADEYPRATHTMNGIQRLIHDLEQKGFAYPADGDVYYSVRNFAEYGKLSGRKLDDLQAGASERVNVEDAEYQKKKDPFDFALWKAAKPSEPAWESPWGKGRPGWHIECSAMVRDRLGDTIDIHAGGADLIFPHHENEIAQSEAVTGKPLANYWLHNGMVKVDGEKMSKSLGNFITIRELLDRGVDPMAVRLFVMMAQYRKPIDFTDEAILAATNGWHTLKEGLLFGYQHSKELGTEKIISSSASSSLSPVTCHLSPNTYVERFKEAVDDDFNFPGGLAVIFELAKELIREGNIIVHQGKTKTPPEELRQHWQTLVTLADILGLTAQPEAETPQQDGLSDGEIDDLIQQRQEARKAKNFAQSDRIRDQLLTKGITLIDSREGTRWHR
>NC_019771.1|WP_150110996.1|1831630_1831798_+|Uma2-family-endonuclease
MQALPTTKPVTFEEFVQWKPEEKYYELHHGVIVELNRPLGNHEWIILFLNDIYQS
>NC_019771.1|WP_015213728.1|1832407_1833517_+|GTP-binding-protein
MQTTATSESHPMEAPKQGLPVTIITGFLGSGKTTLLNHILTNQQGVKTAVLVNEFGEIGIDNELVVSTDENMVELNNGCICCTINNDLVDAVYKVLEREEKLDYLVVETTGLADPLPVAMTFLGSELRDLTRLDSIITVVDAANYSLDLFNSEAALSQITYGDVIILNKTDLVDEDTLQSLEKKINNLKEGSRIIRTTNSQVPLPLILSVGLFESDKYFDAETDEHEHHDHHNEHDHHDDHDHSTCGHDHHDHEHHHHHSDHLENDGFISISFQSDKPLSIRKFQYFLDNQLPTSVFRAKGIMWFDESPQRHIFHLCGKRFTIDDDEWKGEKKNQLVLIGQNLDEDTLIKQLENCICLPSVSRGKGFGK
>NC_019771.1|WP_015213729.1|1833765_1835526_-|alkaline-phosphatase
MAVKSSSQFRLTSSLLAGILTLVIIIVGAIAANSTPVTTTTKNVIIMIGDGMGWEMARAAAMTKGYNYTSGKGEGLSFQTLDNYALATTYGTTVAPGNGVFNTSNSALTNSISITGGSPVLPGFKFQPIFNPGNKPSGGAENPIANAVGNLVGYDPIRGGINPWTPGNDPEYIKHSYPDSANTATTLYTGVKSYNNAISVDIFEKPLETILKTAADVGKSTGIVTSVPIDHATPGAAAANVNRRNKYDSDYPTLDSILQQELRIYQPTVILGGGHPLTGSSSQSLPAGVEPPTKFEYITKSTYAELSKNPNQNRYNYTFLERGKDAAAKLVATASKLDPNKNQRLLGLYGARGQEGNLPVSTANGDYSNTGLSIFSLFSSQGQKPDTVRPLLPGETDKSFIAKEINENPTLKDLTKAALAVLSKDKDGFWLMVEGGDIDWAAHDDNLDNLIGTVLDFDQAVQTTIDWIKNNGGWENNLLIVTADHDHYLTLNPNFEELLKGKGAEALTAEFDPTKAGHFWGSEPQIKYGWGNHANRPVPVYYQGKGAEVLTNFIGKGFKNYGFDVPGVNGLVDQIHIHQTQLAAVK

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Crispr_ID: NC_019771_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_9

2034350-2034496

Orphan

A:N

Consensus_repeat	Method
TGCGATAGCGCAAGCGCTGACTTGTCAGTTCGCTCAAAATCCATTATCTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019771_9

>merge|NC_019771|9|2034350-2034496|CRISPRCasFinder
TGCGATAGCGCAAGCGCTGACTTGTCAGTTCGCTCAAAATCCATTATCTTGTGCTTCCTTAACTACTATTAACTGCGATCGCTAACATTGGGTTAATGCGATAGCGCAAGCGCTGACTTGTCAGTTCGCTCAAAATCCATTGTCTTG

>NC_019771|9|9|2034350-2034496|CRISPRCasFinder
TGCGATAGCGCAAGCGCTGACTTGTCAGTTCGCTCAAAATCCATTATCTTG	TGCTTCCTTAACTACTATTAACTGCGATCGCTAACATTGGGTTAA
TGCGATAGCGCAAGCGCTGACTTGTCAGTTCGCTCAAAATCCATTGTCTTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015213904.1\|2032724_2033351_+\|Curculin-domain-protein-(mannose-binding)-lectin	unknown	unknown	gnl\|CDD\|214519
NC_019771.1\|WP_015213900.1\|2026168_2026552_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213909.1\|2035129_2035462_+\|S1-RNA-binding-domain-protein	unknown	unknown	gnl\|CDD\|273232
NC_019771.1\|WP_015213910.1\|2035652_2035889_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213917.1\|2038538_2038886_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|225216
NC_019771.1\|WP_150111081.1\|2034792_2035125_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213903.1\|2030784_2032245_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271177
NC_019771.1\|WP_015213898.1\|2025032_2025620_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213911.1\|2036387_2036588_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213901.1\|2026610_2027591_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270281
NC_019771.1\|WP_015213897.1\|2023042_2024938_+\|ATP-dependent-zinc-metalloprotease-FtsH	unknown	unknown	gnl\|CDD\|214386
NC_019771.1\|WP_015213914.1\|2037219_2037603_-\|transcription-regulator-with-HTH-domain	unknown	unknown	gnl\|CDD\|227786
NC_019771.1\|WP_015213912.1\|2036587_2036848_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_042465872.1\|2025619_2025865_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213916.1\|2038224_2038542_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213906.1\|2033932_2034259_+\|DUF5615-family-PIN-like-protein	unknown	unknown	gnl\|CDD\|350852
NC_019771.1\|WP_015213905.1\|2033724_2033949_+\|DUF433-domain-containing-protein	unknown	unknown	gnl\|CDD\|377269
NC_019771.1\|WP_015213913.1\|2037012_2037282_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213902.1\|2027600_2029394_+\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|226229
NC_019771.1\|WP_015213915.1\|2037577_2037886_-\|type-II-toxin-antitoxin-system-HigB-family-toxin	unknown	unknown	gnl\|CDD\|378301

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015213904.1\|2032724_2033351_+\|Curculin-domain-protein-(mannose-binding)-lectin	gnl\|CDD\|214519	smart00108, B_lectin, Bulb-type mannose-specific lectin.	5.92915e-18
NC_019771.1\|WP_015213909.1\|2035129_2035462_+\|S1-RNA-binding-domain-protein	gnl\|CDD\|273232	TIGR00717, 30S_ribosomal_protein_S1, ribosomal protein S1. This model describes ribosomal protein S1, RpsA. This protein is found in most bacterial genomes in a single copy, but is not present in the Mycoplasmas. It is heterogeneous with respect to the number of repeats of the S1 RNA binding domain described by pfam00575: six repeats in E. coli and most other bacteria, four in Bacillus subtilis and some other species. rpsA is an essential gene in E. coli but not in B. subtilis. It is associated with the cytidylate kinase gene cmk in many species, and fused to it in Treponema pallidum. RpsA is proposed (Medline:97323001) to assist in mRNA degradation. This model provides trusted hits to most long form (6 repeat) examples of RpsA. Among homologs with only four repeats are some to which other (perhaps secondary) functions have been assigned. [Protein synthesis, Ribosomal proteins: synthesis and modification].	1.84997e-06
NC_019771.1\|WP_015213917.1\|2038538_2038886_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|225216	COG2337, MazF, Growth inhibitor [Signal transduction mechanisms].	1.71356e-27
NC_019771.1\|WP_015213906.1\|2033932_2034259_+\|DUF5615-family-PIN-like-protein	gnl\|CDD\|350852	cd18770, PIN_Mut7-C-like, uncharacterized subgroup of the Mut7-C-like family of the PIN domain superfamily. The Mut7-C-like family of the PIN domain superfamily includes the C-terminal domain of Caenorhabditis elegans Mut-7 (also known as exonuclease 3'-5' domain-containing protein 3 homolog) Mut-7 is involved in RNA interference (RNAi) and transposon silencing in C. elegans. The Mut7-C PIN domain family is recognized as a genuine PIN domain, however it is not included it in the CDD PIN domain superfamily hierarchical model as it is lacks a core strand and helix (H3 and S3). The PIN (PilT N terminus) domain belongs to a large nuclease superfamily, and were originally named for their sequence similarity to the N-terminal domain of an annotated pili biogenesis protein, PilT, a domain fusion between a PIN-domain and a PilT ATPase domain. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons. Other PIN domain families are: the FEN-like PIN domain family which includes the PIN domains of Flap endonuclease-1 (FEN1), Exonuclease-1 (EXO1), Mkt1, Gap endonuclease 1 (GEN1), and Xeroderma pigmentosum complementation group G (XPG) nuclease, 5'-3' exonucleases of DNA polymerase I and bacteriophage T4- and T5-5' nucleases; the VapC-like PIN domain family which includes toxins of prokaryotic toxin/antitoxin operons FitAB and VapBC, as well as, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and, rRNA-processing protein Fcf1; the LabA-like PIN domain family which includes the PIN domains of Synechococcus elongatus LabA (low-amplitude and bright); the PRORP-Zc3h12a-like PIN domain family which includes the PIN domains of of RNase P (PRORP), ribonuclease Zc3h12a; and Bacillus subtilis YacP/Rae1-like PIN domains. Matelska et al. recently classified PIN-like domains into distinct groups; this subgroup includes some sequences belonging to one of these, PIN_16.	4.48336e-25
NC_019771.1\|WP_015213905.1\|2033724_2033949_+\|DUF433-domain-containing-protein	gnl\|CDD\|377269	pfam04255, DUF433, Protein of unknown function (DUF433).	1.04422e-17
NC_019771.1\|WP_015213903.1\|2030784_2032245_+\|site-specific-integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.55332e-35
NC_019771.1\|WP_015213915.1\|2037577_2037886_-\|type-II-toxin-antitoxin-system-HigB-family-toxin	gnl\|CDD\|378301	pfam09907, HigB_toxin, HigB_toxin, RelE-like toxic component of a toxin-antitoxin system. HigB_toxin is a family of RelE-like prokaryotic proteins that function as mRNA interferases. HigB cleaves translated mRNA only, and cleavage depended on translation of the target RNAs. HigB belongs to the RelE super-family of RNases. The toxin-antitoxin gene-pair is induced by environmental stress factors.	7.98769e-30
NC_019771.1\|WP_015213902.1\|2027600_2029394_+\|diguanylate-cyclase	gnl\|CDD\|226229	COG3706, PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms].	5.48593e-54
NC_019771.1\|WP_015213901.1\|2026610_2027591_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270281	cd13563, PBP2_SsuA_like_6, Putative substrate binding domain of sulfonate binding protein-like, a member of the type 2 periplasmic binding protein fold. This subfamily includes the periplasmic component of putative ABC-type sulfonate transport system similar to SsuA. These domains are found in eubacterial SsuA proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding the ligand, SsuA interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The SsuA proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.98625e-55
NC_019771.1\|WP_015213897.1\|2023042_2024938_+\|ATP-dependent-zinc-metalloprotease-FtsH	gnl\|CDD\|214386	CHL00176, ftsH, cell division protein; Validated.	0
NC_019771.1\|WP_015213914.1\|2037219_2037603_-\|transcription-regulator-with-HTH-domain	gnl\|CDD\|227786	COG5499, COG5499, Predicted transcription regulator containing HTH domain [Transcription].	0.000480362

>NC_019771.1|WP_015213906.1|2033932_2034259_+|DUF5615-family-PIN-like-protein
MRILLDECAPRPLKRQLAEYDIKTVVEMGWSGKKNGELLQLMSQEGFTILLTTDQNLRYQQNLQQAGVAVVVLVAQSNKLADLLPLLPDARKVLNTIVPGAVVEVGGS
>NC_019771.1|WP_015213905.1|2033724_2033949_+|DUF433-domain-containing-protein
MALTSPIIHSDPDILGGTPVFVGTRVPIKTLLDYLEAGDSLDVFLDHFPSVTHKQAIAALELAKEMLTAYANPA
>NC_019771.1|WP_015213904.1|2032724_2033351_+|Curculin-domain-protein-(mannose-binding)-lectin
MSSSLKTEQSLGVEQRIVSDNGRYQLVLQSDGNLVLYGLEGRVPGGATWATGTDGQGGTLAVLQSDGNFVLYGPRGRVPGGALWGSGTDGQDVTSLVMQNDGNLVLYRRDGSAAWATDTVEPPPPPPKQAYCCNVFKADGRTRAWQKTLYSSSEAEAYTECLRLKDYVLGPDQPGGIGFGRGVCSSGELKKPEMLLENVDPALPECDR
>NC_019771.1|WP_015213903.1|2030784_2032245_+|site-specific-integrase
MSGQNQGNCEETYSTSTQEYANADSRDWFADMFADFEPQNTTDGSYRGTMAKIKATELQYQAVFEQKLVEANTNLKRERIRVTIKQTGNSLQLRATLPLKPGDYSLGKTKKQYDLSLGIPANLEGLKTAIEESYELGKLIARHTFEWNEKYLGIKSREKQEIKTIGELLDTFDEKYYQTRQKTITSQNTFANYISVIKRNLTLTHLATKENFEEVINSFQGNKKNELIAVTSVLIKTFNLGFQLDVKRDHVTPAYREIPDDEKIISAFDLFEKFALNRKNTNISDEIDTWEMWRWVYGMLATFGLRPRELFVQPDINWWMSPQNIDHTWKVNKNTKTGYREVIPFVPEWIELFDLHNPKPLKILEQKVAKIASVQNINWMRRDISRWFRKVGIEFQPYDLRHGCAIRAHLQGIPIKAAADNLGHTVDEHTKTYQRWFGIENRKKAFGEVISQKSLIELQKNEILALRMENERLRLEVERFKFSKNV
>NC_019771.1|WP_015213902.1|2027600_2029394_+|diguanylate-cyclase
MQHSLLGSIRTKLIVSFLIVALIPLLLLTFINKQTTEKALADNARQALSMAANETANRIDAFIDGNLNSVRVEAILPGFARYLSLTPKQRDDSPEMQLATETLIRLSRKDMVNVLSYALLNLNGKNVLDTYTPNVSKDESGQDYFKEPLQTGLSFVSSMKQSSTIPDLLTFFFSSPVRNAKGDILGVLRVSYNATVVQQLVTRQTERAGAKSFAILLDENNIYLAHSTAPQLLFKSIVPLPLDIVTRLQKAERLPNSPVKELATNEFKLKQALDGKQSYLITSLSGTGNQVNLITIAHLKYKPWSVLFAQPISIALAPVEKQIHDAMFLFALIASVVTIIAFAIGQLITKPIIYLTNIVFQFTAGNLDIRVEMNSKDEIGQLAKSFNNMALQLQTSLETLEQRVQERTAELIIAKEKAEDANQKLEKLVNLDSLTQVANRRCFDGRLQAEWNRLKRERQPLSLILFDVDKFKLYNDYYGHFGGDDCLIRIAQTVQKIVNRPADLVARYGGEEFSVLLPNTDLVEAIKVAQSIQQAIHDQAIPHAKSDVKDIVTLSLGIASLIPTCDIKPDTLITSADKALYNAKRQGRDRYCYSFES
>NC_019771.1|WP_015213901.1|2026610_2027591_+|ABC-transporter-substrate-binding-protein
MLKLLKYLSICFISACLLFACHVWTPTEFKRPPLKIPFGFFVGEYPGIIAQEKGFFKAQGVDVELIHKPYIQLEQGNFSAGKYDGAISSLGSFIILSATIPDIQSVMVVDESTGADVVVAQSQIRTVADLKGKKLGTNLGGFSEVFVTEMLKTANLTSDDVNLVKLEASEIPQRLKNNTIQAGHTWQPHLSEAMKSGGHILFTSKQTPYLILDMIVFRGEIIRDRPEDVRAFVRGWLQAVNYWKANIQEGNAIVSKVLKIPSNTISLEGVNLTDLDENQKFFQSSNPNSIYKNAKIYADFFIRTGNVTRIPELKSLFNSDFLKPPD
>NC_019771.1|WP_015213900.1|2026168_2026552_+|hypothetical-protein
MFDILPFRFELDKIAIAGACLWSLALYLALASTREWVIEQLNRWFNFAERSLYTSQTEFEKTRKARESQNAFYASLFSIMPFFIFGALCNWGLEISLGDSWGISTGILACMGAGIYELGRRDGESSD
>NC_019771.1|WP_042465872.1|2025619_2025865_-|hypothetical-protein
MIDRLQKALDSGQKISDADASFYFHELKEAELMEKGYDWGTAHPMAIAHYGVSQYSFYHPEVIKAYPEDFNRNWRKAWGID
>NC_019771.1|WP_015213898.1|2025032_2025620_-|hypothetical-protein
MLKVLNLGLSGKARIWTDEGFSFPGDFPPVFYPVVNERIEIIDENAKISSFFTREVMIEILAPLGARFLYGCLGAIFEPNDSGKLVLKVAVSTEVEREVKSSLASSLDIVRVGIPEEYANSVFEGSKLKLQEPGVSKIIGSGEISFKWGTFGELGSSRAFFRDLSYTVIEVMVRDKVRANDNINPLFKKVLEQSL
>NC_019771.1|WP_015213897.1|2023042_2024938_+|ATP-dependent-zinc-metalloprotease-FtsH
MTNFGKKTLRKQRPTKRSIWTGALAATMIMMPGILGMNPVLAQKAERNSLTYGELLQKTEQGQVRKVELDETEQIARVYLADQKPDAPPIPVRLLDQNSELINRLKEKNVDFGEVSSANSRAAVGLLINLMWILPLVALMLLFLRRSSNASNQAMNFGKSRARFQMEAKTGVKFDEVAGVEEAKEELQEVVTFLKQPERFTAVGARIPKGVLLIGPPGTGKTLLAKAIAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFKKAKDNAPCIIFIDEIDAVGRQRGAGIGGGNDEREQTLNQLLTEMDGFEGNTGIIIIAATNRPDVLDSALLRPGRFDRQITVDAPDIKGRLEILQVHAKNKKLDPSVSLDAIARRTPGFTGADLANLLNEAAILTARRRKETITISEIDDAVDRVVAGMEGAALVDSKNKRLIAYHEVGHALVGTLIKDHDPVQKVTLIPRGQALGLTWFTPNEEQGLISRSQILARIIAALGGRAAEEIVFGKAEVTTGAGNDLQQVTSMARQMVTRFGMSDLGPLSLESPNQEVFLGRDWGNKSEYSEEIAAKIDTQVREIVNSGYIKAKELLQENRPVLERLVDLLAEQETIDGDLFRQIVEENTQIQVTDQKLAVSR
>NC_019771.1|WP_150111081.1|2034792_2035125_+|hypothetical-protein
MNAITIYKATQKGKGQNLVERGFHPDDFPYHPPTADGKCYFAAPNSRSLAEEYHRYYKDGILEVTIDSEIYEQYFKPLEKPYQGTKQLELPVPHDLFPILNQYPRVLKPR
>NC_019771.1|WP_015213909.1|2035129_2035462_+|S1-RNA-binding-domain-protein
MSNQFWQKIKSKYRLGELIHGTVEYHAPFGIFVSLDDEVVKGLVQITDFVDSGDMTPEMYPDIGSPIGAVVVGYTEDDRHQIWLSVKPSVLQKALVHLKIPATSDRSSAA
>NC_019771.1|WP_015213910.1|2035652_2035889_+|hypothetical-protein
MNLDTIQQDIASLPPDAQQIIVELVEVLKKRYLQNQHESSENSLQDWSDFIGCIEAETDLSKNYKNYLDRQKTISRFS
>NC_019771.1|WP_015213911.1|2036387_2036588_+|hypothetical-protein
MSTIEQIEAAILTLPPEQFQRLRQWILDIDYQHWDEQLEQDIADGKLEALAEEAIAEFKAGHCREL
>NC_019771.1|WP_015213912.1|2036587_2036848_+|hypothetical-protein
MHYTTRRFWKCYDDLPPQVQETADQCYELLKADPSHPSLHFKKIGKKYWSVRAGLDYRALGVEVESGISWFWIGTHAEYDKLIGKL
>NC_019771.1|WP_015213913.1|2037012_2037282_+|hypothetical-protein
MPTASEAIASSGLSAIAQALTCQFAQNPLSCDSLTVINCDLMGKRSLKFYYLVLRDSEALLQAVRNISSLQYQRSQFEGFLRIELTFSV
>NC_019771.1|WP_015213914.1|2037219_2037603_-|transcription-regulator-with-HTH-domain
MMNGLTIPSPYYLSLITEFAPRPITNDLELSITQQRINTILDQKNLSQDDRDYINVLGMLVYDYEEKNEQFPKLTDGELLQTLMEDYNLEIRDFLGIFEQEQTILDILDGKRQLNSQETFKLRSLIL
>NC_019771.1|WP_015213915.1|2037577_2037886_-|type-II-toxin-antitoxin-system-HigB-family-toxin
MRVISRRSLREFWEKHSTAKNSLLLWYDRITKSSIENFAQLRQLFPSADLVGNFTVFNISGNNYRLITYIDYQAQIIFIRDVLIHADYDKENWKNDEWFNNP
>NC_019771.1|WP_015213916.1|2038224_2038542_+|hypothetical-protein
MKAVELAGTVNTNGQINLDQALTLPYGSRVKVIVLLPELIDQVDGDQEIFQPISLNNPKLIDTLKMRTLIETSLTDMANDPEIQREIGLINAEFEISELDGIERL
>NC_019771.1|WP_015213917.1|2038538_2038886_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MSVQRSEIYFVNLNPVQGREQAGERPVLVLSVDAINQLPLVVTVVVGTKGTNITKNYPTNVRCSPEETGLSIETVFLCFQIRSLDLKRFPSQPSGKLSDAKMQDIETVVRYCLGL

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Crispr_ID: NC_019771_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_10

2037981-2038100

Orphan

A:N

Consensus_repeat	Method
TCGCTCAGTATCCATTTCCTTGTACTTCCTTAACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019771_10

>merge|NC_019771|10|2037981-2038100|CRISPRCasFinder
TCGCTCAGTATCCATTTCCTTGTACTTCCTTAACTGCGATCGCTAATATTGGTTAATGCGATAGCGCAAGCGCTGACTTGTCAGTTCGCTCAATATCCATTTCCTTGTACTTCCTTAACT

>NC_019771|10|10|2037981-2038100|CRISPRCasFinder
TCGCTCAGTATCCATTTCCTTGTACTTCCTTAACT	GCGATCGCTAATATTGGTTAATGCGATAGCGCAAGCGCTGACTTGTCAGT
TCGCTCAATATCCATTTCCTTGTACTTCCTTAACT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_150110998.1\|2041146_2043003_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238124
NC_019771.1\|WP_015213922.1\|2043072_2043261_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213918.1\|2039030_2039321_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213909.1\|2035129_2035462_+\|S1-RNA-binding-domain-protein	unknown	unknown	gnl\|CDD\|273232
NC_019771.1\|WP_015213910.1\|2035652_2035889_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213919.1\|2039310_2039694_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_150111081.1\|2034792_2035125_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213911.1\|2036387_2036588_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213916.1\|2038224_2038542_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213914.1\|2037219_2037603_-\|transcription-regulator-with-HTH-domain	unknown	unknown	gnl\|CDD\|227786
NC_019771.1\|WP_171815785.1\|2040104_2040434_+\|aspartyl-protease-family-protein	unknown	unknown	gnl\|CDD\|133136
NC_019771.1\|WP_015213924.1\|2044521_2045193_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|375429
NC_019771.1\|WP_015213912.1\|2036587_2036848_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213917.1\|2038538_2038886_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|225216
NC_019771.1\|WP_015213906.1\|2033932_2034259_+\|DUF5615-family-PIN-like-protein	unknown	unknown	gnl\|CDD\|350852
NC_019771.1\|WP_015213923.1\|2043401_2044133_-\|protein-involved-in-ubiquinone-biosynthesis	unknown	unknown	gnl\|CDD\|227364
NC_019771.1\|WP_015213905.1\|2033724_2033949_+\|DUF433-domain-containing-protein	unknown	unknown	gnl\|CDD\|377269
NC_019771.1\|WP_015213913.1\|2037012_2037282_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213920.1\|2039893_2040112_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015213915.1\|2037577_2037886_-\|type-II-toxin-antitoxin-system-HigB-family-toxin	unknown	unknown	gnl\|CDD\|378301

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_171815785.1\|2040104_2040434_+\|aspartyl-protease-family-protein	gnl\|CDD\|133136	cd00303, retropepsin_like, Retropepsins; pepsin-like aspartate proteases. The family includes pepsin-like aspartate proteases from retroviruses, retrotransposons and retroelements, as well as eukaryotic dna-damage-inducible proteins (DDIs), and bacterial aspartate peptidases. While fungal and mammalian pepsins are bilobal proteins with structurally related N and C-terminals, retropepsins are half as long as their fungal and mammalian counterparts. The monomers are structurally related to one lobe of the pepsin molecule and retropepsins function as homodimers. The active site aspartate occurs within a motif (Asp-Thr/Ser-Gly), as it does in pepsin. Retroviral aspartyl protease is synthesized as part of the POL polyprotein that contains an aspartyl protease, a reverse transcriptase, RNase H, and an integrase. The POL polyprotein undergoes specific enzymatic cleavage to yield the mature proteins. In aspartate peptidases, Asp residues are ligands of an activated water molecule in all examples where catalytic residues have been identified. This group of aspartate peptidases is classified by MEROPS as the peptidase family A2 (retropepsin family, clan AA), subfamily A2A.	0.00510403
NC_019771.1\|WP_150110998.1\|2041146_2043003_+\|hypothetical-protein	gnl\|CDD\|238124	cd00203, ZnMc, Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which are involved in vertebrate development and disease.	1.76103e-08
NC_019771.1\|WP_015213924.1\|2044521_2045193_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|375429	pfam17918, TetR_C_15, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. This entry represents the C-terminal domain found in a number of different TetR transcription regulator proteins including SlmA proteins found in E. coli. Unlike other TetR proteins, SlmA functions not as a transcription regulator but rather as an NO (nucleoid occlusion) factor. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain.	1.4058e-18
NC_019771.1\|WP_015213909.1\|2035129_2035462_+\|S1-RNA-binding-domain-protein	gnl\|CDD\|273232	TIGR00717, 30S_ribosomal_protein_S1, ribosomal protein S1. This model describes ribosomal protein S1, RpsA. This protein is found in most bacterial genomes in a single copy, but is not present in the Mycoplasmas. It is heterogeneous with respect to the number of repeats of the S1 RNA binding domain described by pfam00575: six repeats in E. coli and most other bacteria, four in Bacillus subtilis and some other species. rpsA is an essential gene in E. coli but not in B. subtilis. It is associated with the cytidylate kinase gene cmk in many species, and fused to it in Treponema pallidum. RpsA is proposed (Medline:97323001) to assist in mRNA degradation. This model provides trusted hits to most long form (6 repeat) examples of RpsA. Among homologs with only four repeats are some to which other (perhaps secondary) functions have been assigned. [Protein synthesis, Ribosomal proteins: synthesis and modification].	1.84997e-06
NC_019771.1\|WP_015213917.1\|2038538_2038886_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|225216	COG2337, MazF, Growth inhibitor [Signal transduction mechanisms].	1.71356e-27
NC_019771.1\|WP_015213906.1\|2033932_2034259_+\|DUF5615-family-PIN-like-protein	gnl\|CDD\|350852	cd18770, PIN_Mut7-C-like, uncharacterized subgroup of the Mut7-C-like family of the PIN domain superfamily. The Mut7-C-like family of the PIN domain superfamily includes the C-terminal domain of Caenorhabditis elegans Mut-7 (also known as exonuclease 3'-5' domain-containing protein 3 homolog) Mut-7 is involved in RNA interference (RNAi) and transposon silencing in C. elegans. The Mut7-C PIN domain family is recognized as a genuine PIN domain, however it is not included it in the CDD PIN domain superfamily hierarchical model as it is lacks a core strand and helix (H3 and S3). The PIN (PilT N terminus) domain belongs to a large nuclease superfamily, and were originally named for their sequence similarity to the N-terminal domain of an annotated pili biogenesis protein, PilT, a domain fusion between a PIN-domain and a PilT ATPase domain. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons. Other PIN domain families are: the FEN-like PIN domain family which includes the PIN domains of Flap endonuclease-1 (FEN1), Exonuclease-1 (EXO1), Mkt1, Gap endonuclease 1 (GEN1), and Xeroderma pigmentosum complementation group G (XPG) nuclease, 5'-3' exonucleases of DNA polymerase I and bacteriophage T4- and T5-5' nucleases; the VapC-like PIN domain family which includes toxins of prokaryotic toxin/antitoxin operons FitAB and VapBC, as well as, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and, rRNA-processing protein Fcf1; the LabA-like PIN domain family which includes the PIN domains of Synechococcus elongatus LabA (low-amplitude and bright); the PRORP-Zc3h12a-like PIN domain family which includes the PIN domains of of RNase P (PRORP), ribonuclease Zc3h12a; and Bacillus subtilis YacP/Rae1-like PIN domains. Matelska et al. recently classified PIN-like domains into distinct groups; this subgroup includes some sequences belonging to one of these, PIN_16.	4.48336e-25
NC_019771.1\|WP_015213923.1\|2043401_2044133_-\|protein-involved-in-ubiquinone-biosynthesis	gnl\|CDD\|227364	COG5031, COQ4, Uncharacterized protein involved in ubiquinone biosynthesis [Coenzyme metabolism].	7.87115e-58
NC_019771.1\|WP_015213905.1\|2033724_2033949_+\|DUF433-domain-containing-protein	gnl\|CDD\|377269	pfam04255, DUF433, Protein of unknown function (DUF433).	1.04422e-17
NC_019771.1\|WP_015213915.1\|2037577_2037886_-\|type-II-toxin-antitoxin-system-HigB-family-toxin	gnl\|CDD\|378301	pfam09907, HigB_toxin, HigB_toxin, RelE-like toxic component of a toxin-antitoxin system. HigB_toxin is a family of RelE-like prokaryotic proteins that function as mRNA interferases. HigB cleaves translated mRNA only, and cleavage depended on translation of the target RNAs. HigB belongs to the RelE super-family of RNases. The toxin-antitoxin gene-pair is induced by environmental stress factors.	7.98769e-30
NC_019771.1\|WP_015213914.1\|2037219_2037603_-\|transcription-regulator-with-HTH-domain	gnl\|CDD\|227786	COG5499, COG5499, Predicted transcription regulator containing HTH domain [Transcription].	0.000480362

>NC_019771.1|WP_015213915.1|2037577_2037886_-|type-II-toxin-antitoxin-system-HigB-family-toxin
MRVISRRSLREFWEKHSTAKNSLLLWYDRITKSSIENFAQLRQLFPSADLVGNFTVFNISGNNYRLITYIDYQAQIIFIRDVLIHADYDKENWKNDEWFNNP
>NC_019771.1|WP_015213914.1|2037219_2037603_-|transcription-regulator-with-HTH-domain
MMNGLTIPSPYYLSLITEFAPRPITNDLELSITQQRINTILDQKNLSQDDRDYINVLGMLVYDYEEKNEQFPKLTDGELLQTLMEDYNLEIRDFLGIFEQEQTILDILDGKRQLNSQETFKLRSLIL
>NC_019771.1|WP_015213913.1|2037012_2037282_+|hypothetical-protein
MPTASEAIASSGLSAIAQALTCQFAQNPLSCDSLTVINCDLMGKRSLKFYYLVLRDSEALLQAVRNISSLQYQRSQFEGFLRIELTFSV
>NC_019771.1|WP_015213912.1|2036587_2036848_+|hypothetical-protein
MHYTTRRFWKCYDDLPPQVQETADQCYELLKADPSHPSLHFKKIGKKYWSVRAGLDYRALGVEVESGISWFWIGTHAEYDKLIGKL
>NC_019771.1|WP_015213911.1|2036387_2036588_+|hypothetical-protein
MSTIEQIEAAILTLPPEQFQRLRQWILDIDYQHWDEQLEQDIADGKLEALAEEAIAEFKAGHCREL
>NC_019771.1|WP_015213910.1|2035652_2035889_+|hypothetical-protein
MNLDTIQQDIASLPPDAQQIIVELVEVLKKRYLQNQHESSENSLQDWSDFIGCIEAETDLSKNYKNYLDRQKTISRFS
>NC_019771.1|WP_015213909.1|2035129_2035462_+|S1-RNA-binding-domain-protein
MSNQFWQKIKSKYRLGELIHGTVEYHAPFGIFVSLDDEVVKGLVQITDFVDSGDMTPEMYPDIGSPIGAVVVGYTEDDRHQIWLSVKPSVLQKALVHLKIPATSDRSSAA
>NC_019771.1|WP_150111081.1|2034792_2035125_+|hypothetical-protein
MNAITIYKATQKGKGQNLVERGFHPDDFPYHPPTADGKCYFAAPNSRSLAEEYHRYYKDGILEVTIDSEIYEQYFKPLEKPYQGTKQLELPVPHDLFPILNQYPRVLKPR
>NC_019771.1|WP_015213906.1|2033932_2034259_+|DUF5615-family-PIN-like-protein
MRILLDECAPRPLKRQLAEYDIKTVVEMGWSGKKNGELLQLMSQEGFTILLTTDQNLRYQQNLQQAGVAVVVLVAQSNKLADLLPLLPDARKVLNTIVPGAVVEVGGS
>NC_019771.1|WP_015213905.1|2033724_2033949_+|DUF433-domain-containing-protein
MALTSPIIHSDPDILGGTPVFVGTRVPIKTLLDYLEAGDSLDVFLDHFPSVTHKQAIAALELAKEMLTAYANPA
>NC_019771.1|WP_015213916.1|2038224_2038542_+|hypothetical-protein
MKAVELAGTVNTNGQINLDQALTLPYGSRVKVIVLLPELIDQVDGDQEIFQPISLNNPKLIDTLKMRTLIETSLTDMANDPEIQREIGLINAEFEISELDGIERL
>NC_019771.1|WP_015213917.1|2038538_2038886_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MSVQRSEIYFVNLNPVQGREQAGERPVLVLSVDAINQLPLVVTVVVGTKGTNITKNYPTNVRCSPEETGLSIETVFLCFQIRSLDLKRFPSQPSGKLSDAKMQDIETVVRYCLGL
>NC_019771.1|WP_015213918.1|2039030_2039321_+|hypothetical-protein
MAELKLRSKDPDSLRRIIESALSERLQSVIAGIKRTEERIIELETKYQLSTKEFINRFNNDELSHNFDFDEWIGESRMLTHLQQMKESIEEIVFVN
>NC_019771.1|WP_015213919.1|2039310_2039694_+|hypothetical-protein
MLIEDYFQQIQLLIESSEIVKIFKIESEKRGIYEGLIRGKIDFQDNSLLHLREFVYVEVSIDRKMYSYQYMNSENNLIFRYDNTEHHRKLNLPTFPHHKHDGSENNVIKSDAPFLDEVLNEVKKILG
>NC_019771.1|WP_015213920.1|2039893_2040112_+|hypothetical-protein
MPLVELMSQIQTLPKIDKLRLMQFLATELVKEEDANFFVANQEYPVWSPYNCSEAANILMNLLATKQQEKNG
>NC_019771.1|WP_171815785.1|2040104_2040434_+|aspartyl-protease-family-protein
MVDAQRFPYKIIDSSLGMVDRMPHLPLTLGYNGHSLKVEGLLDTGASVNVLPYEIGKQLGFIWENETLSVILAGNLAQFEARAVVVDAQVGSFPTINLAFAWTQATNVP
>NC_019771.1|WP_150110998.1|2041146_2043003_+|hypothetical-protein
MKTLTRFSMTTSLPLLTSKKLKQISALFLFSSSAISTLIFPLAGRAQDIGKIEQPLIVERSNLWSARQISVCWETGGNNVEKQWVRDAIAQTWEKESSARFINWGDCQNNSKGIRIQLADVRPHTKGLGDELDGKTNGMVLNITYASWQSSCQDGGAQPTGFSNPNRIPSSTEREFCTKVIASHEFGHALGFDHEHTRDDNPDAKCSDDAGGGGSGDWKITPYDLRSIMNYCNPAWNGDGNLSDRDIEGLVQLYGRNPNSVANIQSDVSAISPVEGASTVFTVGEEGNIWSAYYDPRVANPQWTGSFRLSPTNATKSNYVTAVSPTRGGSTLFTVGTDGAVWSAYYDPRVANPKWTGWFSLGGKVRPGSKIAAVSATEGGVSLFIVGSDNAVWSAYYDPRVANPKWNGWFSLGGKVRSDADVKAISSVEGGISLFVIGLDSAVWSAYYDPRVANPKWSDWFSLGGLVRPNTNVSPVSTTRGGISLFTVSIDSAVWSAYYDPRVANPKWSGWFSLGGQVRLNTNVSPVSSIEGGVSLFTVGVDNSVWSAYYDPRIANAKWSNWFSLGGSVPTTRNVSAISATKGGVTLFTKGNDGYIRSAYYDPRVANPKWTDWFTVGR
>NC_019771.1|WP_015213922.1|2043072_2043261_+|hypothetical-protein
MNNWTVEQIAFRCDTYGVREASRRERSYRLSVRLERLAQNFLQMASLSLDGVNGEAVINCDR
>NC_019771.1|WP_015213923.1|2043401_2044133_-|protein-involved-in-ubiquinone-biosynthesis
MQLLNSATSNASVNTNLQKQTQNPIVQGLMSILSKLLIVKSSLSMLFGDNSLETVGELTYGLLATTAYDLVAQHLNQDIACATLIRDRYIPPAHDLEYLLTLPSNSLGYIYAAQIKKMGFDPNLHAGMTAKSDAEYVELRLSQTHDLWHIVTGFDTSLNSEIGLQAFHLPQFPYPLGTMLVAISLISTTLQEPEMLPKLLEAIAQGFQMGKTAKPLFAQKWEEGWEKPLTQWQEELNIQPIRN
>NC_019771.1|WP_015213924.1|2044521_2045193_+|TetR-family-transcriptional-regulator
MSESSSPAGGMRRKPRQARSQERVNRILDVAEGLFASQGYAATTTNAIAAQAQVPIGSLYQFFPDKTAILQALSLRYAEMLHQELVFIDKAETVTLPLADYVNQLIDTTDRFFTDNPSYYAIFMEVQGTIRELDEIDEATDAKLIQDLASSLANRDARLEHADYEAIAFVLVKAIGTLLWLSLSQEPLYRQRLVAETKRLSLHYLQSYFSSELIPANNPAGAD

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Crispr_ID: NC_019771_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_11

2468661-2468764

Orphan

A:N

Consensus_repeat	Method
TGATGGCTATACAATTCTTGATGCTTCTGAGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019771_11

>merge|NC_019771|11|2468661-2468764|CRISPRCasFinder
TGATGGCTATACAATTCTTGATGCTTCTGAGTCATTATCATTGGCAGCAGGTCATAAACAAGAGTTAGCGGCTGATGGCTATACAATTCTTGATGCTTCTGAGT

>NC_019771|11|11|2468661-2468764|CRISPRCasFinder
TGATGGCTATACAATTCTTGATGCTTCTGAGT	CATTATCATTGGCAGCAGGTCATAAACAAGAGTTAGCGGC
TGATGGCTATACAATTCTTGATGCTTCTGAGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015214277.1\|2472086_2472863_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|238038
NC_019771.1\|WP_015214265.1\|2457156_2457429_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015214279.1\|2477479_2478643_-\|DUF3854-domain-containing-protein	unknown	unknown	gnl\|CDD\|372412
NC_019771.1\|WP_015214264.1\|2456761_2457031_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370460
NC_019771.1\|WP_015214276.1\|2470362_2470899_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|224321
NC_019771.1\|WP_015214280.1\|2478914_2479235_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015214283.1\|2480712_2480982_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_150111091.1\|2459209_2459518_-\|DUF1311-domain-containing-protein	unknown	unknown	gnl\|CDD\|377758
NC_019771.1\|WP_015214282.1\|2480395_2480665_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015214269.1\|2459976_2460486_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_150111005.1\|2465458_2465764_+\|fertility-inhibition-FinO-like-protein	unknown	unknown	unknown
NC_019771.1\|WP_015214281.1\|2479968_2480235_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_042464852.1\|2481063_2481390_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227439
NC_019771.1\|WP_015214270.1\|2461138_2461936_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|371375
NC_019771.1\|WP_015213536.1\|2474102_2474672_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
NC_019771.1\|WP_150111092.1\|2461984_2463208_-\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NC_019771.1\|WP_015214273.1\|2464787_2465228_+\|cyanase	unknown	unknown	gnl\|CDD\|235079
NC_019771.1\|WP_015214267.1\|2457912_2458995_-\|photosystem-II-q(b)-protein	unknown	unknown	gnl\|CDD\|130221
NC_019771.1\|WP_015214272.1\|2463929_2464526_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|179877
NC_019771.1\|WP_085930377.1\|2474676_2476323_+\|IS481-family-transposase	unknown	unknown	gnl\|CDD\|366234

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015214277.1\|2472086_2472863_+\|HNH-endonuclease	gnl\|CDD\|238038	cd00085, HNHc, HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and anaredoxins.	0.00081045
NC_019771.1\|WP_015214279.1\|2477479_2478643_-\|DUF3854-domain-containing-protein	gnl\|CDD\|372412	pfam12965, DUF3854, Domain of unknown function (DUF3854). A family of uncharacterized proteins found by clustering human gut metagenomic sequences. This domain is likely to be related to the Toprim domain.	8.00195e-41
NC_019771.1\|WP_015214264.1\|2456761_2457031_+\|hypothetical-protein	gnl\|CDD\|370460	pfam09386, ParD, Antitoxin ParD. ParD is a plasmid anti-toxin than forms a ribbon-helix-helix DNA binding structure. It stabilizes plasmids by inhibiting ParE toxicity in cells that express ParD and ParE. ParD forms a dimer and also regulates its own promoter (parDE).	7.34245e-05
NC_019771.1\|WP_015214276.1\|2470362_2470899_+\|HNH-endonuclease	gnl\|CDD\|224321	COG1403, McrA, Restriction endonuclease [Defense mechanisms].	8.75682e-28
NC_019771.1\|WP_042464852.1\|2481063_2481390_+\|hypothetical-protein	gnl\|CDD\|227439	COG5108, RPO41, Mitochondrial DNA-directed RNA polymerase [Transcription].	0.00308799
NC_019771.1\|WP_150111091.1\|2459209_2459518_-\|DUF1311-domain-containing-protein	gnl\|CDD\|377758	pfam07007, LprI, Lysozyme inhibitor LprI. This family consists of several bacterial proteins of around 120 residues in length. Members of this family contain four highly conserved cysteine residues. Family members include lipoprotein LprI from Mycobacterium, which binds to and inhibits macrophage lysozyme, which may aid bacterial survival.	2.34644e-09
NC_019771.1\|WP_015214270.1\|2461138_2461936_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|371375	pfam11103, DUF2887, Protein of unknown function (DUF2887). This bacterial family of proteins has no known function. These proteins may be distantly related to the PD(D/E)XK superfamily.	9.94094e-100
NC_019771.1\|WP_015213536.1\|2474102_2474672_+\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	1.04102e-57
NC_019771.1\|WP_150111092.1\|2461984_2463208_-\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.25442e-73
NC_019771.1\|WP_015214273.1\|2464787_2465228_+\|cyanase	gnl\|CDD\|235079	PRK02866, PRK02866, cyanate hydratase; Validated.	6.36e-84
NC_019771.1\|WP_015214267.1\|2457912_2458995_-\|photosystem-II-q(b)-protein	gnl\|CDD\|130221	TIGR01151, Photosystem_QB_protein, photosystem II, DI subunit (also called Q(B)). This model describes the Photosystem II, DI subunit (also called Q(B)) in bacterial and its equivalents in chloroplast of algae and higher plants. Photosystem II is many ways functionally equivalent to bacterial reaction center. At the core of Photosystem II are several light harvesting cofactors including plastoquinones, pheophytins, phyloquinones etc. These cofactors are intimately associated with the polypeptides, which principally including subunits DI, DII, Cyt.b, Cyt.f and iron-sulphur protein. Together they participate in the electron transfer reactions that lead to the net production of the reducting equivalents in the form of NADPH, which are used for reduction of CO2 to carbohydrates(C6H1206). Phosystem II operates during oxygenic photosynthesis and principal electron donor is H2O. Although no structural data is presently available, a huge body of literature exits that describes function using a variety of biochemical and biophysical techniques. [Energy metabolism, Electron transport, Energy metabolism, Photosynthesis].	0
NC_019771.1\|WP_015214272.1\|2463929_2464526_+\|hypothetical-protein	gnl\|CDD\|179877	PRK04778, PRK04778, septation ring formation regulator EzrA; Provisional.	0.0043587
NC_019771.1\|WP_085930377.1\|2474676_2476323_+\|IS481-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.703e-08

>NC_019771.1|WP_150111005.1|2465458_2465764_+|fertility-inhibition-FinO-like-protein
MMITGKLEVTIKINELPEATTIENGWQQFEVDCDGRIISVTVKPKVWKKLTDAQANYPQWVGAIAGKLGEATDNGFVLLEPNIQTFEKKAKTPAADAATAS
>NC_019771.1|WP_015214273.1|2464787_2465228_+|cyanase
MSIPEITQTLLEAKKEKGLSFADLEKILGLDEVYIAAIFYRQASASPEEAKLLVEALDLAPIYIQELTKYPVKGLGPVVPTDPLIYRFYEIMQVYGFPIKEVIQEKFGDGIMSAIDFTLDVEKEVDPKGDRVKITMSGKFLPYKKW
>NC_019771.1|WP_015214272.1|2463929_2464526_+|hypothetical-protein
MATKDWLNNHAKVTAYLDFSLYASLEKWMQKHKIKKASQALTIILEHYLEGNIPIEVMPENLEQEVKRLKVKTTEIDSLEATVAEQQREFNDEINSLRTEIDELRQALINAGLSSLKEKVEDIPRGQIKFSYSDEDVKQGLTKTDLCERIDINGSTINQWATMLNLDSDEYLFELTGWKKPPNTRRYFPVKDNESNPK
>NC_019771.1|WP_150111092.1|2461984_2463208_-|ISL3-family-transposase
MKILTEILDLSGVKVVSHRLHTGIGMILQIEQENSFATCPYCGTTSHKLHQNHRHIIKDLPFGEKEIFLEINRRQFKCEQCKKPFSEDLDFVKKKRTFTNRLANKTIQEVLENDIHSVAAKGIVTKDEIERMLKDASSELPDLKPINLKRLGIDEIALKKGHGNYCAVLVDLDQSKLIAILSGRTQEIIRGTLMGWGTEILENIEEVSIDLWSGYKTLVTELMPNAQVVADRFHVMTQINKELDTQRKREKRKVEDLIKKANTTEKSKYEEILAGLKNSKYPLLKNEDKLTQEQLEKLIQVKNVSPILKEMHEFKEKIRQIFNTTQDWYTGVFKLGMWLSRAKKYFPNSNNTIIRWYQEIIAYFDNRTTSGTVEGINNKLKLIKRSGYGFKNFENFRIRCLLSWHYV
>NC_019771.1|WP_015214270.1|2461138_2461936_-|Rpn-family-recombination-promoting-nuclease/putative-transposase
MKRDTIYYQIFKRFPALLFELVDYRPEQAYNYRFESVEVKETAFRIDGVFLPPEGATPKVIFFAEVQFQKDEALYHRFFTESLMYLYRNQSNYDDWYCVVIFPSRSLEPSDTKTHRLFLNSDQVQRIYLDELGTPNILPIGINLMQLTIASEKEMALQARLLIERVQLESTDALPKNEIIDIITTIAVYKFSSLSREEVEAMLGLTLEQTRVYQEAKAEGREEREAEMLKLTVPLLLKTGMSVEQIAQQLNVDVEVIRLAAQQSA
>NC_019771.1|WP_015214269.1|2459976_2460486_+|hypothetical-protein
MLKPQDIVVSLKVHNLRSQVWTYSGLANSLHMSQSEVHAALKRCEVSGLYDSASKKIRKPALLEFLIHGLKYVFPGQPGALSRGMPTAHSAEPLKSLLVVDPADAYVWPAPDGTVRGQTITPLYKSVPAAAKDDSELYELLSLIDALRVGRAREQRLAAQELEQRLVHE
>NC_019771.1|WP_150111091.1|2459209_2459518_-|DUF1311-domain-containing-protein
MYNKCLKAAGVTNNSSVAQCSLQTFNASEQEINRLYSKIYHQIASQQAEDAKKFELSQKFWLSYRDSHCKLAGAYVGSPMYSYCPMQLNILRVAELREFAIE
>NC_019771.1|WP_015214267.1|2457912_2458995_-|photosystem-II-q(b)-protein
MTTAIQQRQSANVWDRFCEWITSTENRIYIGWFGVLMIPTLLSAIACFVIAFIAAPPVDIDGIREPVAGSLLYGNNIISGAVVPSSNAIGLHFYPIWEAASLDEWLYNGGPYQLVIFHFLIGVACYLGREWELSYRLGMRPWICVAFSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLVRETTETESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVIGIWFTALGVSTMAFNLNGFNFNQSIIDSQGRVIGTWADVINRANLGMEVMHERNAHNFPLDLAAGDVAPVALTAPAING
>NC_019771.1|WP_015214265.1|2457156_2457429_+|hypothetical-protein
MKEEAHKEDIEVITQVLAKITTLSPEQIKPYLDTMLERLVKPQAERPLYETATPFELSQAFQEWADSHDRNTPLLSDYAVSRESMYSDEE
>NC_019771.1|WP_015214264.1|2456761_2457031_+|hypothetical-protein
MAETKRTSKLSLKPGVKTTPVIDEQAAWVESRNGVEASIPKEEPSNSKMKRITFEVTETQHQTIKICATKKGMSIKELMISLIEQELKD
>NC_019771.1|WP_015214276.1|2470362_2470899_+|HNH-endonuclease
MEAQPPFQQTHILQNSVVVFSKNYLPLSRINIKRAIVLLVTGQAESLNFDTTKQWEIRSPSVVLQVPEHIRLTVGNPERHWKIPPVNRREVLKRDNHTCQYCGSTKRLTLDHVIPRSKGGQHTWDNVVTACDKCNSIKSDRLLYEAGMVLKTKPKAPIHPAVAFAEQFWNAQRLTEKE
>NC_019771.1|WP_015214277.1|2472086_2472863_+|HNH-endonuclease
MRYRSVLSNKTKVEEAVKRCSSVRECLHFLGLRSAGGNYKQFYCWCEKHGIIPPKGKNINGLNNASKQAQIPLEKILILGSSYNRNSLKSRLIQESLLEERCYECGILSKWNEKPLCLQLDHINGIANDNRIENLRLLCPNCHSQTLTFAGKRKPYSRIVFYSCSNCYASITKSSKLGLCKRCASLRSNLKRRKVERPSKEELHELLWSKPTSLVAKELGVSDKAIEKWCKSYGIPKPPRGYWNKQNQLQGLIVNQTL
>NC_019771.1|WP_015213536.1|2474102_2474672_+|recombinase-family-protein
MLIGYARISTDDQNLNLQMDALQLAGCEKIYSDRTSGAKAERPGLSLALEVARTGDVLVVWRLDRLGRSLKDLIEMMETLDKRGIGLSSLQESITTTNNSGRLIFHLFGALAEFERNLIRERTTAGLVAARGRGHRGGRPKALDPTKRQLAVRLYTEKQYTIIEICNLMGISKPTLYNYIAEIKTEHGT
>NC_019771.1|WP_085930377.1|2474676_2476323_+|IS481-family-transposase
MSVEALINLRHRLDGLPSRCQERRILIEETAALYGVSTDTLYRALRNSSRPKSINRSDSGTPRKLSLAEMERYCEVIAAMKIRTSNKKGRHISTVRAIELLEEFGMETPDGFVQPDKGALTRSTVNYYLKTWGYDQERMTRQPPAVRFQAEYSNECWHFDLSPSDLKHVKQPSWVEPGRGNPLLMLYSIVDDRSGLCYQEYHCVYGEDVEAALRFLFNAMTAKTTDGFAFQGIPEMIYTDNGPIAKSHVFQNVMDCLRINLVTHMPAGKDGRRVTARSKGKVERPSRTVKEAHETLYHFHEPESDIEANLWLRQYLLHYNDKPHRIEPHSRLEDWLRNIPKSGLRSMCSWERFCTFAREPQRRKVGTDARVSVEGVAYEVEPDLAGETVVPWWGLFDNELYVEKEDRRYGPFYPVDGPIPLHRYRKFKKTKTEERADKIANLAKKLGLPRTALDKNTDLQFLVDKYKELEPTVTPFNDPDPYQEFTYPTVLFAKRAISEQLARPLAKLSPEQLAFIDALLAETLNKKAIIERVRQYFRSNQGEEQNAH
>NC_019771.1|WP_015214279.1|2477479_2478643_-|DUF3854-domain-containing-protein
MTTRKKNGEATTSPTTKNIKSTTIVAEKDAKSLTDSQIDTSKTVNLQNKFTSFEEFKSFAKDLFINGSGIDPELFADIEFHESIEWTDGMDAEAPIHDELGWYFTRFGYQVKEPIYAAFLRNEDGSLWQVMVSLWDEDRQRPYRYLAPKGNGDRAFTPPVPEPIRKKVASRSGMNVPMEGSFWDWVREAKIPRIITEGGKKALAALSQGYVTIGLYGCRCGAGKSKDEDGINLEPSLTPDLERLAVENSIWLLAMDRDDSHKAKISVTKGKKRLTLALKAANPSYVEDIFWRTEQGKGIDDLIVNSGTGAFDRAYSDAIARLEKTFKSGTPQNDEPEKHKNPPPDQMAKEIAEDYRHMIAFNDETKSWMRYEADANGVWSPESNEYM
>NC_019771.1|WP_015214280.1|2478914_2479235_-|hypothetical-protein
MKVINEKSQAQRERGTQKECGYRPDRDCVGGVRLSSSNSECQPITSNRDDRTGGTSGGDAITAITGGILEQLILESKEELTNSEARVNQLHDRIKLLESLKASLDI
>NC_019771.1|WP_015214281.1|2479968_2480235_+|hypothetical-protein
MLSTDILRENVENIVSAPSKKREQRVSELLRAMDTLNDLIRHQELIRMALEECNTDNRITLLLDLYLMISDSSLEDISGTLERLQASL
>NC_019771.1|WP_015214282.1|2480395_2480665_+|hypothetical-protein
MTRKKQSKDTPVMKSGKKGYSLIDNKEMLSLHMTIDYLAHLLSEEWKGDKKKLIYKARETSWEFIDQQDDNKIEEQANEIINHLANPDE
>NC_019771.1|WP_015214283.1|2480712_2480982_+|hypothetical-protein
MTRKQSKDTPIMRSNKKGYSLVEHRRFLSLNVISDILIWRLSEELKCDEKEVKEWAIREAKSIVKSWDDEGVEKAINKIIENSENLKIG
>NC_019771.1|WP_042464852.1|2481063_2481390_+|hypothetical-protein
MSEKPYSFIEGIDWDYVPSHSLTQSEISIYSKWLGLPIKQFTPVTLHLNLPKNHEEYGDTLSDFLKEKYPSVWEQLLLRAAGDYALRSYLAGYFKEEIDLWLKDKLTN

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Crispr_ID: NC_019771_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_12

2700759-2700868

Orphan

A:N

Consensus_repeat	Method
AATCCTGTAAATCCTCAAATCCTGGACAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019771_12

>merge|NC_019771|12|2700759-2700868|CRISPRCasFinder
AATCCTGTAAATCCTCAAATCCTGGACATCCTGATTCAGACAATTAAAATTTCCGCATCCCACCAACAACTTACAAATCACAATCTTGTAAATCCTCAAATCCTGGACAT

>NC_019771|12|12|2700759-2700868|CRISPRCasFinder
AATCCTGTAAATCCTCAAATCCTGGACAT	CCTGATTCAGACAATTAAAATTTCCGCATCCCACCAACAACTTACAAATCAC
AATCTTGTAAATCCTCAAATCCTGGACAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015214481.1\|2702302_2703532_+\|protein-glutamate-O-methyltransferase-family-protein	unknown	unknown	gnl\|CDD\|376673
NC_019771.1\|WP_015214489.1\|2712558_2713032_-\|DUF29-domain-containing-protein	unknown	unknown	gnl\|CDD\|366774
NC_019771.1\|WP_015214480.1\|2701381_2701966_+\|Uma2-family-endonuclease	unknown	unknown	gnl\|CDD\|99749
NC_019771.1\|WP_015214479.1\|2700239_2700539_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015214482.1\|2703983_2705552_+\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|277324
NC_019771.1\|WP_042464916.1\|2709834_2712432_-\|chloride-channel-protein	unknown	unknown	gnl\|CDD\|238504
NC_019771.1\|WP_015214484.1\|2705989_2706367_-\|phage-holin-family-protein	unknown	unknown	gnl\|CDD\|224861
NC_019771.1\|WP_015214477.1\|2698067_2699672_+\|murein-biosynthesis-integral-membrane-protein-MurJ	unknown	unknown	gnl\|CDD\|223800
NC_019771.1\|WP_015214470.1\|2688490_2689471_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226952
NC_019771.1\|WP_015214478.1\|2699847_2700243_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015214473.1\|2693599_2694664_-\|mannose-1-phosphate-guanylyltransferase	unknown	unknown	gnl\|CDD\|223906
NC_019771.1\|WP_015214483.1\|2705699_2705891_-\|YqaE/Pmp3-family-membrane-protein	unknown	unknown	gnl\|CDD\|376592
NC_019771.1\|WP_015214476.1\|2696967_2697903_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015214487.1\|2709430_2709637_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015214475.1\|2696372_2696879_+\|pentapeptide-repeat-containing-protein	unknown	unknown	gnl\|CDD\|224276
NC_019771.1\|WP_015214472.1\|2691519_2693166_-\|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl\|CDD\|223733
NC_019771.1\|WP_015214474.1\|2694779_2696285_+\|LCP-family-protein	unknown	unknown	gnl\|CDD\|224235
NC_019771.1\|WP_015214471.1\|2689674_2691321_-\|AAA-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|373105
NC_019771.1\|WP_015214485.1\|2706492_2706819_-\|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|177056
NC_019771.1\|WP_015214486.1\|2707023_2709183_-\|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl\|CDD\|225094

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015214481.1\|2702302_2703532_+\|protein-glutamate-O-methyltransferase-family-protein	gnl\|CDD\|376673	pfam01937, DUF89, Protein of unknown function DUF89. This family has no known function.	5.26066e-76
NC_019771.1\|WP_015214489.1\|2712558_2713032_-\|DUF29-domain-containing-protein	gnl\|CDD\|366774	pfam01724, DUF29, Domain of unknown function DUF29. This family consists of various hypothetical proteins from cyanobacteria, none of which are functionally described. The aligned region is approximately 120-140 amino acids long corresponding to almost the entire length of the proteins in the family. Structure 3fcn is a small protein that has a novel all-alpha fold. The N-terminal helical hairpin is likely to function as a dimerization module. This protein is a member of PFam family PF01724. The function of this protein is unknown. One protein sequence contains a fusion of this protein and a DnaB domain, suggesting a possible role in DNA helicase activity (hypothetical). Dali hits have low Z and high rmsd, suggesting probably only topological similarities (not functional relevance) (details derived from TOPSAN). The family has several highly conserved sequence motifs, including YD/ExD, DxxNVxEEIE, and CPY/F/W, as well as conserved tryptophans.	1.04856e-64
NC_019771.1\|WP_015214480.1\|2701381_2701966_+\|Uma2-family-endonuclease	gnl\|CDD\|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	5.03596e-30
NC_019771.1\|WP_015214482.1\|2703983_2705552_+\|metallophosphoesterase	gnl\|CDD\|277324	cd07378, MPP_ACP5, Homo sapiens acid phosphatase 5 and related proteins, metallophosphatase domain. Acid phosphatase 5 (ACP5) removes the mannose 6-phosphate recognition marker from lysosomal proteins. The exact site of dephosphorylation is not clear. Evidence suggests dephosphorylation may take place in a prelysosomal compartment as well as in the lysosome. ACP5 belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	0.000235483
NC_019771.1\|WP_042464916.1\|2709834_2712432_-\|chloride-channel-protein	gnl\|CDD\|238504	cd01031, EriC, ClC chloride channel EriC. This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked proton utilization. As shown for Escherichia coli EriC, these channels can counterbalance the electric current produced by the outwardly directed virtual proton pump linked to amino acid decarboxylation. The EriC proteins belong to the ClC superfamily of chloride ion channels, which share a unique double-barreled architecture and voltage-dependent gating mechanism. The voltage-dependent gating is conferred by the permeating anion itself, acting as the gating charge. In Escherichia coli EriC, a glutamate residue that protrudes into the pore is thought to participate in gating by binding to a Cl- ion site within the selectivity filter.	3.51644e-151
NC_019771.1\|WP_015214484.1\|2705989_2706367_-\|phage-holin-family-protein	gnl\|CDD\|224861	COG1950, COG1950, Predicted membrane protein [Function unknown].	9.38643e-26
NC_019771.1\|WP_015214477.1\|2698067_2699672_+\|murein-biosynthesis-integral-membrane-protein-MurJ	gnl\|CDD\|223800	COG0728, MviN, Uncharacterized membrane protein, putative virulence factor [General function prediction only].	6.78117e-110
NC_019771.1\|WP_015214470.1\|2688490_2689471_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226952	COG4586, COG4586, ABC-type uncharacterized transport system, ATPase component [General function prediction only].	5.33865e-170
NC_019771.1\|WP_015214473.1\|2693599_2694664_-\|mannose-1-phosphate-guanylyltransferase	gnl\|CDD\|223906	COG0836, {ManC}, Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane].	2.07714e-154
NC_019771.1\|WP_015214483.1\|2705699_2705891_-\|YqaE/Pmp3-family-membrane-protein	gnl\|CDD\|376592	pfam01679, Pmp3, Proteolipid membrane potential modulator. Pmp3 is an evolutionarily conserved proteolipid in the plasma membrane which, in S. pombe, is transcriptionally regulated by the Spc1 stress MAPK (mitogen-activated protein kinases) pathway. It functions to modulate the membrane potential, particularly to resist high cellular cation concentration. In eukaryotic organisms, stress-activated mitogen-activated protein kinases play crucial roles in transmitting environmental signals that will regulate gene expression for allowing the cell to adapt to cellular stress. Pmp3-like proteins are highly conserved in bacteria, yeast, nematode and plants.	4.37692e-16
NC_019771.1\|WP_015214475.1\|2696372_2696879_+\|pentapeptide-repeat-containing-protein	gnl\|CDD\|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	7.97325e-13
NC_019771.1\|WP_015214472.1\|2691519_2693166_-\|AarF/ABC1/UbiB-kinase-family-protein	gnl\|CDD\|223733	COG0661, AarF, Predicted unusual protein kinase [General function prediction only].	4.70341e-153
NC_019771.1\|WP_015214474.1\|2694779_2696285_+\|LCP-family-protein	gnl\|CDD\|224235	COG1316, LytR, Transcriptional regulator [Transcription].	6.85327e-64
NC_019771.1\|WP_015214471.1\|2689674_2691321_-\|AAA-like-domain-containing-protein	gnl\|CDD\|373105	pfam14516, AAA_35, AAA-like domain. This family of proteins are part of the AAA superfamily.	0
NC_019771.1\|WP_015214485.1\|2706492_2706819_-\|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	gnl\|CDD\|177056	CHL00134, petF, ferredoxin; Validated.	1.33718e-39
NC_019771.1\|WP_015214486.1\|2707023_2709183_-\|RNA-binding-transcriptional-accessory-protein	gnl\|CDD\|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0

>NC_019771.1|WP_015214479.1|2700239_2700539_-|hypothetical-protein
MNTLEKLELLSENCTDNTELERIIGQLLNVILTRHRQKLAIYNLDIDKFEKKYNLTSEQFEQQFNSGNLGDEMDFFEWFSLCELRKDILQKIKKLKQAL
>NC_019771.1|WP_015214478.1|2699847_2700243_-|hypothetical-protein
MKNADDYLAWVKSVIALCPEVVILKIIREESQLDKGLWRYRLTLKDGSFLEMFEFFKRASGQIEIIKYSFHWQTENGQLIKRWDNAPHHPEISTYPHHIHDGSEDSVFPYLPVDIEEIVKKVSEQIKSESS
>NC_019771.1|WP_015214477.1|2698067_2699672_+|murein-biosynthesis-integral-membrane-protein-MurJ
MTQSEQKPARSFAGIAGIVAAATLISKIFGLVRQQAIAAAFGVGAAATAYSYAYIIPGFLLILLGGVNGPLHSAIVSVLAKRKREEAAPLVETVTTIVGGLLLVVTVAQIFLAEPIIDIVGYGLEPTTRAIAIRQLQIMAPMALFSGLIGIGFGTLNAANQYWLLSISPLLSSITVIAGIGILTLQYGKDIIKPEFALIGGMVLAWGTLAGAILQWIVQLIVQWRLGLGTLKLRFDFKSPAVQEVIKIMTPATISSGMMPINVATDLYFASPIKGAAAGFNYANLLVQTPLGIISNIILLPLLPIFAKLAEPENWSDLKLRIRQGLLLTAVTMLPLGALMIALSEPIVQVIYQRGAFKQEATELVSSLLVAYGIGMFVYLARDVLVRVFYALGDGQTPFKISIFNILLNAGLDFVLVKPFGAPGLVLATVSVNCSSILMLLWLLNRKLNGLPLREWSLPILGLTAGSMVAGVASYGTLVACQQVLGNKGLVILLVELSISGLVGIGVFAVVAAWLRIPEVNSFVVKMRQKFLKR
>NC_019771.1|WP_015214476.1|2696967_2697903_+|hypothetical-protein
MDSKDPLLQAVLLITNLWLFWYFIKGKTIKVDEQTQAKLDFTIQPKLLRFIGLFIGQIAIICLYSTLIATPITQLNCNRVPQNIDSSIIAKSTEQKTSLVICKLVELDWFSHEKSQKHISELIGASLEKQSETDSDGKKIYYKYRIQLITNTESFPFRQAYRASRFIHEELESIISQINNFLAQPLEKKLLVQEDDRSILVAITIFFSLLPLIIIGAGLFISCNFNKEANSLILSRYRWFGIFGKGFSQYSLNEIVNIKVESRDSDEGGFTYRVILILESGEIVPLSHVYSSGFEEKQQIVNIVKTFLSQK
>NC_019771.1|WP_015214475.1|2696372_2696879_+|pentapeptide-repeat-containing-protein
MKKILLRFLTLLLILMLAFFWVIINPKPAFAQVNTINYNNASLENSDFSHTDLVGGTFVAAEMRGANFQGANLSNAILTKGVLLKANLEDANLTGALVDRVTLDSANLKNAIFTEATLTRSRFYDADITGADFTDALIDRYQVSLLCERANGVNSVTGISTRDSLGCR
>NC_019771.1|WP_015214474.1|2694779_2696285_+|LCP-family-protein
MIKQVQWSDNQVIPQQVPASGQEVRPQQFQRTEPQRPDPIPGSTGQEVRAKQPVNPLNVVDSVGAIPHELYDRLGLTMPRWLLWILTFVVGIILSGLLVSTLALWTPLWSNLDQAKDDDFGSTTNKDQVKVPGDLWRKLSQYQLSKPMNILVMGIEPVKGTVDGSPESFAGSSDTMLLIRLNPSDKSIRILSIPRGTMISIPEQGLTKVSEANAKGGPVLAARVVSRTLSNAPIDRYIRISTSGLRQLVEQLGGVDVFVPQAMNYQDKSGGLSVNLASGWQSLNGEQAEQFARFRDSNVGDIPRVQRQQALITALLQRLNSPTVLPRLPQLTRIMRKYFDTNLKMEEMMALANFSVNVERDNFQMAMLPGTFSKFSKDPNSYWLNMTGQQSLMNDYVGVNVPGLKSDDRPVSRLKIAIQNASNQPQLTEKVITYLKSKGFTNIYAVPDWPDTQRQTQIIVQKGNPQPGVDLQEVLGLGQIEVSANGDLESDLTIRIGKDWK
>NC_019771.1|WP_015214473.1|2693599_2694664_-|mannose-1-phosphate-guanylyltransferase
MNNSLIPVILAGGKGERFWPLSRQDRPKQFLSLDGSSRSLLQATADRLLTLAGGWNNLWVITSSQIAEGVRQQLPDLPKQNLLIELEGRDTAAAVAWTSLEIKKRYGEDAVIGFFPADHWIADQEAFAHTLNAAIQLATSTAAIVTLGIKPTFPSTGYGYIEQGEKIGSFNDLPAYHVNRFTEKPNRETAETFLSTGQFSWNSGMFVFRAGVVLEELRIHAPEILEPLEQKGPDIYPQLPKKSIDYALMEKTSLAYVLPVDFGWDDLGDWNAIARLHQKADNPNVELATHVGLDTQGSVVYASNPDDVVVTIGLEDVVIVRDRNVTLIVKKERTQDIKQILKTLQSDPRFTDLL
>NC_019771.1|WP_015214472.1|2691519_2693166_-|AarF/ABC1/UbiB-kinase-family-protein
MFLTQTVPRQREIIEVVLRNGWDYMRSLLTGGKTDEPQLPTPAVLKNILVDLGPVYVKLGQLLSTRPDLLSAGYIEELSTLQDEVPPVPWSEVEIVIRKQLKRPLEETFRIINHFPVAAGSIAQTHRATLADGKEVALKVQRPGIDITIAQDIALIQGIADLVARTDFGQNYDIKSIAEEFTKALEAELDFKREAGFTDQLRRNLSASRWYDPTQIVVAEINWHLTTEKLLVMEWLDGVPILSADLSINHNEQDLIPARKAITTLLFRVFFQQIYIDGFFHADPHPGNLFYLIDGRVALLDCGMVGRLDPRTQQILTEMLLAIVDLDAQRCAQLTLQLSDSAQPVILAKLENDYDRMLRKYYNASLTDINFSRVIYEILQIARNNKIRLPSNMGLYAKTLANLEGVARTFNPEVNLFDEIKPLITDLFSRQLLGESPVRSLLRTALDIKSLSLQSPRQIELLLDRVTSETLQWNLSLQGLDGVRRTMDDAANRLSFSILVGSLIMGAAMISSRATTSQLSYVSSILFAAASLLGLWLIISILRSGRLR
>NC_019771.1|WP_015214471.1|2689674_2691321_-|AAA-like-domain-containing-protein
MEENILLPGDPLPFNSRFYIERPPIERDAYTELTKPGALLRIRASYNMGKSSLMLRLIHQAMNQGYIIASIDFQQADSQIFTSLNKFLRWFCMNIARQLSLTPNLNDYWDEDIGSKVSASIYFEGYLLKQIQSPLVLVLNEVNYIFEHLHIAKDFLPLLRSWHEKAKQTKIWQKLRLVVIHATEVYIPLNVNQSPFNVGLCLKIPEFNAEQVTEFARRHDLNWFDTSAVKQLMDLIGGHPYLIHLAFYHIQQQKISFPELLATAISHNGIYSHHLRYLLTILQSNEELSVAFYKIINSQKPTRISANLIYKLDSLGLIKQLGSDNFQPACEMYRLFFQKETLIAENNTSIRLEKLEEENEKLKFLLNIDKLTQIANRRYFDNRFQLEWERMKRTQEPIALILADIDKFKLFNDTYGHQAGDDCLSQVAQAINSVIKRADDLVARYGGEEFVVILPQTDSKGAIIIAEEIRKKVKLWEIKIPNFTQYSQETNVTKVTISLGVACIIPQASLGLKELFEAADQALYQAKQVGRDRTILSSQFCYCNLSYK
>NC_019771.1|WP_015214470.1|2688490_2689471_-|ATP-binding-cassette-domain-containing-protein
MSIIIAENLSKYYPVAIKEPGIRGTLTHFFRRTYRSIKAVQDVSFEIASGEVVGFLGPNGAGKTTTLKMLTGLIHPSSGTVRVAGHIPFRRQEAFLQKITLVMGQKQQLIWDLPALDSLRINAAVYNISDREFQHRVGELTEMLSLEGKLNQPVRKLSLGERMKAELLAALLHRPQVLFLDEPTLGLDVNAQVSVRDFLRDYNQLYQATVLLTSHYMADITALCKRVLLIHQGKLMYDGSLDGLLENFAPYREIYVELAHPLPAEKLMSYGDIQLLEGRAVRFIVQRAALTSTVSQILADLEVIDLTVTEPPVEEVIGRVFQNGFV
>NC_019771.1|WP_015214480.1|2701381_2701966_+|Uma2-family-endonuclease
MQTQTRHYTPEEYLELEEKAEYKSEYRDGEIIPMTGGTTNHNKIAGNFYAYLKFALKKKNYDVYIGDVRLWIPRYRQHTYPDVMVIQGEPIYTGSNTTTVMNPLLIAEVSSKSTSNYDQSDKFLYYRSIPEFKEYILINQYQHHVMQYVKTDDGKWIFTEYESESDILKLQTVDFQIAFTDLYEQVNFTQSIEE
>NC_019771.1|WP_015214481.1|2702302_2703532_+|protein-glutamate-O-methyltransferase-family-protein
MNKPQIPNLPLPASLIGADAGSFTEYTVTQRMPDIARRVIIENKFPTEINQGLEKLAAELPSGYLQSLIDDTGVDFNDWNKYIEPYKGQRWVDIPWFVAETYFYRLILNITNYFQPGEWQSVDPFGLQKIQGLETSIDSIISLCTQTQEWLNASQQEDKPSKSSLIALLYFALWGNRVDLSLWSAFEDDRSRFNIQTQLSNILVDDTFAITKLLTKSENNCIDLVVDNAGFELICDLCLVDFLLGSGFASQVYLHLKPHPTFVSDAMIKDVHYTKNFLIQSSNIQVKSLGQRLTKNLASGRLVLTEDYFWTSPLAFWEIPKSLKDELGKSNLMIVKGDTNYRRLLGDLNWDFTTNFAEIVSYLPAPMVALRTLKSEVAAGLKSDVMEELAIVDPNWLTNGQWGVIQLVN
>NC_019771.1|WP_015214482.1|2703983_2705552_+|metallophosphoesterase
MKLISEPSVPVKIQKMKQRVRWMHPSIKERGIDQTSLILDDGKEESPDFSFMVIGDSGTKSDYGQHPQRQVMEMLLSNNDDCRFVLHTGDVVYLVGSREYYPANFIEPYREFIVGGENPKSIAYDQMVFKLPILPVLGNHDYYDVPLLYRLVTGSTLSLRRMLRYKDIEVGWHGSNQGDAYTRAFIDYLARMSPNDLKLHLDEYYTAKTDTGRCLRYQPGNFTRLPNRYYTFRYGGIDFFALDSNTFNTPAPLPGNEAGDVFRRELLQRRQELEREELQILAECDKLNSENTVEAEQLADLVAKVDQLNEVKIDIDKQLEPHTSADVDFEQLDWLRSRLIESWHSSNVRGRVIFFHHPPYVTEATKWQQGQTLAVRHRLRGVFEQVGATLDKMTQGRPVVDVIFNGHAHCLEHLRTGNTGYADSHINYIVCGGSGRRPRRQRQEGTQLMETFNDAAGVSTRKVADSLLYVGRSGYGSERRKPYSCVRVDVKAGFPAKFVVTPLVTERIEGEWCDRSLEPFII
>NC_019771.1|WP_015214483.1|2705699_2705891_-|YqaE/Pmp3-family-membrane-protein
MKLTRLLLGLFLPPVGVFMTVGVSPTLGINILLTLLGWLPGSIHALWVITKHDERLNREEGTF
>NC_019771.1|WP_015214484.1|2705989_2706367_-|phage-holin-family-protein
MWGIFITTLATALSLLIVDIIFPGVDIANFPAALIAGLVIGLINGSVKPILTTLSLPLTFLTLGGFSLVVNGICFWLASVLVPGFRVQGLIAFILAPVILSLANTFLSKYFAERNVELQSKTTES
>NC_019771.1|WP_015214485.1|2706492_2706819_-|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein
MTIYQVRLINEKLGLDRTIQVPEDQYIIDIAEEKGIRIPSGCKQGECSACIAKLISGEIDQSEQKFLRPQEIQAGYVITCVTYPLSDCVLETHQEQTLYKSSLYYKPE
>NC_019771.1|WP_015214486.1|2707023_2709183_-|RNA-binding-transcriptional-accessory-protein
MLNIPQLLATELELNPNQVQNALELLAEGATIPFIARYRKERTNEMNEVQLRDLFDRYTYLTELAERKKVILNAIAEQGKLSDELKAKITTCLQKTELEDLYLPYKPKRRTRATIAREKGLETLAAYIKSLNVKNCVAAPLEEEAAKYISETLGVKTAGEALKGAADILAEEVAEKAELRSYVRDYLLETGVFISRIKNDHPEGTTKFEMYRNYQIKVKNIAPHNMLALCRGEAEKILSFEIAFDEDFVLSYLESQEIKAKIRAIRDFYQTMLKDAFNRLMKTSLIGEVISEKKTYSDVESIKTFEANLRELLLSAPAGMKPTLAIDPGFRTGCKVAVLEQTGKFLEYQAVFPHQAAEQRKKAAQTIKSLIEKYKIELIAIGNGTASRETDEFVSEVLEICERKPVKVMVNESGASIYSASKVALEEFPDLDITVRGAISIGRRLQDPLAELVKIDPKSIGVGQYQHDVDQKLLKKKLDETVESCVNYVGVDLNTASKELLTFVSGITPAVANNIIAYRNQNGAFKNRRQLLKVAKLGPKAFEQAAGFLRIRSGENPLDSTAVHPESYSLIESIAKDLNVSLNQVTEIAEKLKKTNIKKYVTDTIGEPTLRDILSELEKPGRDPRAEFKYATFKAGIKEIRDLQVGMELEGIITNVANFGAFVDIGVHQDGLVHISQLADRFVDDPQKIVKVGQVVKVQILEVNEKLKRIGLSMKAVKQ
>NC_019771.1|WP_015214487.1|2709430_2709637_+|hypothetical-protein
MPLFFLIPICTGLVTGYFLNQKDEIAYIAGVFTAVSLILSLILAPWQIQLGLLMIVLFVSKKLLQKIY
>NC_019771.1|WP_042464916.1|2709834_2712432_-|chloride-channel-protein
MLLQMLTQRFRLLWQPRRGLAIAEACIIGIVAALSAVLLKQGSGWLGTWRVHSTQVLPAWLTLPIIGMVFGFLAGWLVQRLAPEAAGSGIPQVKATLANIPMKLSWRVALIKLLSTIISLGSGITLGRQGPTVQIGAGLAAGMSRWVPTSPEHRRQMIAAGAGAGLAAAFNAPIAGVLFIIEELLQDLSGLTLGTAIIASFIGGVISRLLGGGSLQLNLQLMEYSSSFSLLEIPVFLILGVLAGLLGALFNQGLVFSIKVYRRLHVSLPLRVALAGFVSGLIVALLPESYRDNTGLREYMITSEANLPFAAIAFIAQFILTLIAFGSGAPGGLFAPSLILGSCLGHLVGVCEFHLWGLGSLTTYALAGMGGFFSAVSKVPMTAIVIVFEMTTDFNLVLPLMIVSVTSYLVADKVVPGSLYDKLLLLKGITIQKDAPIEGILTQLTAKNVMQQRVETLETDMAVEEVIQAFSRSHHRGFPVVENCKLVGIVTQSDLQNRYLSHGISLREIMTPQPVTVKPTQTLSDVLYLLDRYQISRLPVVERQKLIGIITRADIIRAEADHINGENRVNGPQPEPSYVVYQTRSPSIGRGRLLVTLANPDTAETLLQMAATIARDRHYELECLQIILVSRHSSPSETQVSTTKSRRLLRQAEALAKKWHIPIHTQIRVAHDVAQAVLETIKERHIDLIFMGWKGNTSTPGRIFGTVVDTVIRQASCDVVLVKLGNISDCSHFNRWLVPMAGGPNARAAIKLLPALVTLGNDAQIRLMQVFKPSELKPDMIVLEESTRQLMRHRNLHSTVVASPIQADSVAEGVIDLVKTESYDVVVLGASREGLLQQAIQGNIPETIASGVESTVILVRGANNS
>NC_019771.1|WP_015214489.1|2712558_2713032_-|DUF29-domain-containing-protein
MTSIETTTNQLPTNSLYEQDFYIWIETTIKILRDRQFNQLDIDNLIEEIETMGRSEKRELINRLRVLIEHLLKLIYWEQVRVENQRGWLDTIVEQRRQIQELLKDSPSLKPLLSEIFTECYTNARKDVLIKTNFPSNKIPTDLSFTLEQTLDINYLP

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Crispr_ID: NC_019771_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_13

3250545-3251389

TypeV-U5

A:N

Consensus_repeat	Method
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	PILER-CR
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CRISPRCasFinder
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CRT

11 spacers

c2c5_V-U5

The CRISPR arrays of NC_019771_13

>merge|NC_019771|13|3250545-3251389|PILER-CR,CRISPRCasFinder,CRT
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAACTTAAAACTAGGTATCAAGGGTGGGTAGAAGCTAAACTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAACCAAGCTTTGACAAGAATGTTTTTGGAAGGAGAGAAGCCTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAACCCAGCAGCACAGGTGTGTAACGTCATGCAAGAATTGGTTGCTACAATCTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAACGTAAATTCTTGATTCCAAGCTAATCTAATTCCCAGCTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAACTAACATTGAATTGTTAGACATATCAGATCGTATTCACCTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAACAAACTGCTAGAACACGCTGCATTTTACAAAGCTCAACTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAACCGTTAGCTTCTGGGTCAAAAGTTAAGTCTTTAACCTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAACTGTGTAAGAGTTTCAGGCAATTGTACGCATGGGAACTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAACAGTGCTATTTGGGATGCAGCAAAACCAAGACTTGACTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAACCGGCTGTTTATGTTAATAAAAAGGCTTTCTTGTTTCTCTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAACCAACTTTTAAAGCAAAATCAAAGTAGTACTTTGCTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC

>NC_019771|13|5|3250545-3251389|PILER-CR
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	TTAAAACTAGGTATCAAGGGTGGGTAGAAGCTAAA
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CAAGCTTTGACAAGAATGTTTTTGGAAGGAGAGAAGC
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CCAGCAGCACAGGTGTGTAACGTCATGCAAGAATTGGTTGCTACAAT
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	GTAAATTCTTGATTCCAAGCTAATCTAATTCCCAG
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	TAACATTGAATTGTTAGACATATCAGATCGTATTCAC
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	AAACTGCTAGAACACGCTGCATTTTACAAAGCTCAA
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CGTTAGCTTCTGGGTCAAAAGTTAAGTCTTTAAC
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	TGTGTAAGAGTTTCAGGCAATTGTACGCATGGGAA
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	AGTGCTATTTGGGATGCAGCAAAACCAAGACTTGA
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CGGCTGTTTATGTTAATAAAAAGGCTTTCTTGTTTCT
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CAACTTTTAAAGCAAAATCAAAGTAGTACTTTG
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC

>NC_019771|13|13|3250545-3251389|CRISPRCasFinder
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	TTAAAACTAGGTATCAAGGGTGGGTAGAAGCTAAA
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CAAGCTTTGACAAGAATGTTTTTGGAAGGAGAGAAGC
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CCAGCAGCACAGGTGTGTAACGTCATGCAAGAATTGGTTGCTACAAT
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	GTAAATTCTTGATTCCAAGCTAATCTAATTCCCAG
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	TAACATTGAATTGTTAGACATATCAGATCGTATTCAC
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	AAACTGCTAGAACACGCTGCATTTTACAAAGCTCAA
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CGTTAGCTTCTGGGTCAAAAGTTAAGTCTTTAAC
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	TGTGTAAGAGTTTCAGGCAATTGTACGCATGGGAA
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	AGTGCTATTTGGGATGCAGCAAAACCAAGACTTGA
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CGGCTGTTTATGTTAATAAAAAGGCTTTCTTGTTTCT
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CAACTTTTAAAGCAAAATCAAAGTAGTACTTTG
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC

>NC_019771|13|4|3250545-3251389|CRT
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	TTAAAACTAGGTATCAAGGGTGGGTAGAAGCTAAA
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CAAGCTTTGACAAGAATGTTTTTGGAAGGAGAGAAGC
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CCAGCAGCACAGGTGTGTAACGTCATGCAAGAATTGGTTGCTACAAT
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	GTAAATTCTTGATTCCAAGCTAATCTAATTCCCAG
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	TAACATTGAATTGTTAGACATATCAGATCGTATTCAC
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	AAACTGCTAGAACACGCTGCATTTTACAAAGCTCAA
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CGTTAGCTTCTGGGTCAAAAGTTAAGTCTTTAAC
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	TGTGTAAGAGTTTCAGGCAATTGTACGCATGGGAA
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	AGTGCTATTTGGGATGCAGCAAAACCAAGACTTGA
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CGGCTGTTTATGTTAATAAAAAGGCTTTCTTGTTTCT
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC	CAACTTTTAAAGCAAAATCAAAGTAGTACTTTG
CTTTCAACCCGCCCCACTCCGGGAGGGGTGTTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015214915.1\|3244005_3247140_+\|translation-initiation-factor-IF-2	unknown	unknown	gnl\|CDD\|235401
NC_019771.1\|WP_015214912.1\|3241874_3243152_+\|transcription-termination-factor-NusA	unknown	unknown	gnl\|CDD\|237063
NC_019771.1\|WP_052334522.1\|3263340_3263769_+\|DUF45-domain-containing-protein	unknown	unknown	gnl\|CDD\|307807
NC_019771.1\|WP_015214919.1\|3251852_3253760_-\|hypothetical-protein	c2c5_V-U5	-	unknown
NC_019771.1\|WP_015214916.1\|3247715_3247913_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015214911.1\|3241293_3241755_+\|ribosome-maturation-factor-RimP	unknown	unknown	gnl\|CDD\|234627
NC_019771.1\|WP_015214924.1\|3260044_3263344_+\|type-I-restriction-endonuclease-subunit-R	unknown	unknown	gnl\|CDD\|223683
NC_019771.1\|WP_042465015.1\|3258962_3260021_+\|macro-domain-containing-protein	unknown	unknown	gnl\|CDD\|394873
NC_019771.1\|WP_015214918.1\|3249938_3250208_-\|DUF3493-domain-containing-protein	unknown	unknown	gnl\|CDD\|371841
NC_019771.1\|WP_015214909.1\|3238829_3239408_-\|peptidoglycan-binding-protein	unknown	unknown	gnl\|CDD\|225943
NC_019771.1\|WP_015214921.1\|3256939_3258268_+\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|341167
NC_019771.1\|WP_015214917.1\|3248231_3249860_+\|DUF1565-domain-containing-protein	unknown	unknown	gnl\|CDD\|284923
NC_019771.1\|WP_015214913.1\|3243242_3243515_+\|YlxR-family-protein	unknown	unknown	gnl\|CDD\|377288
NC_019771.1\|WP_171815790.1\|3243666_3243867_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015214910.1\|3239663_3241109_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015214922.1\|3258272_3258908_+\|DUF4433-domain-containing-protein	unknown	unknown	gnl\|CDD\|373093
NC_019771.1\|WP_015214920.1\|3253827_3254256_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133380
NC_019771.1\|WP_015214925.1\|3265573_3266077_-\|TniQ-family-protein	unknown	unknown	gnl\|CDD\|377670
NC_019771.1\|WP_150111014.1\|3269022_3270726_-\|Mu-transposase-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|378147
NC_019771.1\|WP_015212748.1\|3266596_3268264_-\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015214915.1\|3244005_3247140_+\|translation-initiation-factor-IF-2	gnl\|CDD\|235401	PRK05306, infB, translation initiation factor IF-2; Validated.	0
NC_019771.1\|WP_015214912.1\|3241874_3243152_+\|transcription-termination-factor-NusA	gnl\|CDD\|237063	PRK12329, nusA, transcription termination factor NusA.	0
NC_019771.1\|WP_052334522.1\|3263340_3263769_+\|DUF45-domain-containing-protein	gnl\|CDD\|307807	pfam01863, DUF45, Protein of unknown function DUF45. This protein has no known function. Members are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C-terminus being the most conserved region, containing three conserved histidines. This motif is similar to that found in Zinc proteases, suggesting that this family may also be proteases.	6.24749e-19
NC_019771.1\|WP_150111014.1\|3269022_3270726_-\|Mu-transposase-C-terminal-domain-containing-protein	gnl\|CDD\|378147	pfam09299, Mu-transpos_C, Mu transposase, C-terminal. Members of this family are found in various prokaryotic integrases and transposases. They adopt a beta-barrel structure with Greek-key topology.	6.64191e-18
NC_019771.1\|WP_015214924.1\|3260044_3263344_+\|type-I-restriction-endonuclease-subunit-R	gnl\|CDD\|223683	COG0610, COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	3.34363e-135
NC_019771.1\|WP_042465015.1\|3258962_3260021_+\|macro-domain-containing-protein	gnl\|CDD\|394873	cd02901, Macro_Poa1p-like, macrodomain, Poa1p-like family. Macrodomains are found in a variety of proteins with diverse cellular functions, as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Macrodomains can recognize ADP-ribose (ADPr) in both its free and protein-linked forms, in related ligands, such as O-acyl-ADP-ribose (OAADPr), and even in ligands unrelated to ADPr. Members of this family show similarity to the yeast protein Poa1p, reported to be a phosphatase specific for Appr-1"-p, a tRNA splicing metabolite. Poa1p may play a role in tRNA splicing regulation.	2.50587e-35
NC_019771.1\|WP_015214918.1\|3249938_3250208_-\|DUF3493-domain-containing-protein	gnl\|CDD\|371841	pfam11998, DUF3493, Protein of unknown function (DUF3493). This family of proteins is functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 79 to 331 amino acids in length.	5.85931e-31
NC_019771.1\|WP_015214909.1\|3238829_3239408_-\|peptidoglycan-binding-protein	gnl\|CDD\|225943	COG3409, COG3409, Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane].	7.50136e-07
NC_019771.1\|WP_015214921.1\|3256939_3258268_+\|restriction-endonuclease-subunit-S	gnl\|CDD\|341167	cd17278, RMtype1_S_LdeBORF1052P-TRD2-CR2, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to Lactobacillus delbrueckii subsp. bulgaricus S subunit (S2.LdeBORF1052P) TRD2-CR2. The recognition sequence of Lactobacillus delbrueckii subsp. bulgaricus S subunit (S2.LdeBORF1052P) is undetermined. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one heteromeric enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	3.28592e-43
NC_019771.1\|WP_015214917.1\|3248231_3249860_+\|DUF1565-domain-containing-protein	gnl\|CDD\|284923	pfam07602, DUF1565, Protein of unknown function (DUF1565). These proteins share a region of homology in their N termini, and are found in several phylogenetically diverse bacteria and in the archaeon Methanosarcina acetivorans. Some of these proteins also contain characterized domains such as pfam00395 and pfam03422.	1.13714e-34
NC_019771.1\|WP_015214913.1\|3243242_3243515_+\|YlxR-family-protein	gnl\|CDD\|377288	pfam04296, DUF448, Protein of unknown function (DUF448).	6.64455e-26
NC_019771.1\|WP_015214911.1\|3241293_3241755_+\|ribosome-maturation-factor-RimP	gnl\|CDD\|234627	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed.	1.48963e-55
NC_019771.1\|WP_015214922.1\|3258272_3258908_+\|DUF4433-domain-containing-protein	gnl\|CDD\|373093	pfam14487, DUF4433, Domain of unknown function (DUF4433). This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 201 and 230 amino acids in length. There is a single completely conserved residue E that may be functionally important. This family is distantly similar to pfam01885 suggesting these may be ADP-ribosylases.	2.61339e-87
NC_019771.1\|WP_015214920.1\|3253827_3254256_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133380	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators. Helix-turn-helix (HTH) transcription regulator GlnR and related proteins, N-terminal domain. The GlnR and TnrA (also known as ScgR) proteins have been shown to regulate expression of glutamine synthetase as well as several genes involved in nitrogen metabolism. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	1.42469e-20
NC_019771.1\|WP_015214925.1\|3265573_3266077_-\|TniQ-family-protein	gnl\|CDD\|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	9.88989e-10
NC_019771.1\|WP_015212748.1\|3266596_3268264_-\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	3.89526e-51

>NC_019771.1|WP_015214918.1|3249938_3250208_-|DUF3493-domain-containing-protein
MIDPNSQNRLNSKQYAHLKAEIAAPYRGLRQFIYIGVGASGFIGAFTFFFQLLAGKNIDSTLPNFALQVGIVALMIFLWKWEQSRQKRL
>NC_019771.1|WP_015214917.1|3248231_3249860_+|DUF1565-domain-containing-protein
MKYRGLHISTLTLGTSLTALLVITGASMLLSSTVNASSRPTLTAQIPASATVIYVNPVTGNDRNSFGTTPEAPYKTITFAISRAQSNTVIQLAPGSYTKDTGETFPLLLKPGVILLGNEAIKGQGTAIIGGGYYTSRTFARQDITILAENNTTITGVTVTNPNSRGTGIWVESSNPTIKNSTFTNSARDGVFITGTGNPKIENNVFVKNQGNGVSVTKSAQGEIRNNLFQDTGFGLAIGGAATTLVAGNNIVGNNDGMFISESAQPVLRNNVIQNNKRDGIVATIDALPNLGTNDNPGGNLIRDNARYDLNNSTKVNRIVAIGNDIDQKRIFGAVDFVAATVNQPGGPVVFRDVPTGYWAKTYIEALAAQNIIAGFPDGTFRPNEPVTRAQFATIITKALTPPAKRTAIQFRDVNSNFWAYGAIQSAYQSQFVAGYPDGTFKPQQQIPRVQALVALANGLNFTANNNNILSFYTDAVQIPNYALGPVAAATVRQLVINYPMVQQLDPNREATRAEIAAFVYQSLVTIGRAQPIPSPYLVTAQ
>NC_019771.1|WP_015214916.1|3247715_3247913_+|hypothetical-protein
MAQISASSTGQFSRDAQFWHNLKNAISTSSGFQRWQLECTAQLQGLRLEQQVQKYLRETLETLAY
>NC_019771.1|WP_015214915.1|3244005_3247140_+|translation-initiation-factor-IF-2
MNNGKVRIYELSKELNLDNKELLAICDQLNIAVKSHSSTISESEAEQIRMAAEKLAATSVSPKKELGTNNHKPNSPQTGGRNRPAASHKQQILEIRKPKILRNTTSNAPEASIDINNQVASSDSLSDIRDSAQEASAMANSPSPPRPFATPVSPMKPTAPTRPVPRNQSETPQKPNIAEPDQPTNNANPVGEKPEKVVSPRAKPEKAQKPQLVSPPSRPPEETESATEQLVPAIKPVLKRERPTRGEDERDQAKPRSKPNTDQKARSTPSPLKPEHRASRPSAPGTTDVQRPRPARPGESPATPTATPPRHTVGAGAKKEGLDDNTPIAPDLLDLKRPTPPRLAKGGKKWQEEEIIDEIKEKAKIGPKGKRVKPILDDDFEEDDLLDEEGLEIPATVQVSLSIARPPKPKSTRPAQQPTLVAAAPTTRNNKKSGSSYRDNNRRQQEAEVKQERPEKLVVTGPLTVQELAEGLAVADTEIVKILFMKGMAVSITQNLDIPTITLVAKELEVEVEITEPEAEARKVTEMIDVTDLEHLIRRPPVVTIMGHVDHGKTTLLDSIRKTKVAAGEAGGITQHIGAYHVDLEHDGKKQQIVFLDTPGHEAFTAMRARGARVTDIAILVVAADDGVRPQTIEAISHAQAAGVPIVVAINKIDKEGAQPERVKQELTNYGLTAEDWGGETIMVPVSAIKGENLDTLLEMILLVAEVGELSANPNRVAKGTVIEAHLDKAKGAVATLLIQNGTLHVGDMLVAGSAFGKVRAMVDDRGKRVDVASPSCAVEVLGLSDVPAAGDDFEVFENEKVARTLASDRADKQRLSRLLQGRVTLTTLSAQAQEGELKELNLILKGDVQGSVEAIIGSLKQIPQNEVQIRMLLATAGEITETDIDLAAASNAVIIGFNTTFASGARQAADEAGVDVREYNIIYKLLEDIQGALEGLLEPELVEEPLGQTEVRAVFPVGRGAVAGCYVQSGKLLRNCKVRVRRGSKVVYEGVLDSLKRMKEDAREVNSGYECGINIDKFHDWVEGDIIEAYQMVTKRRTLTLTK
>NC_019771.1|WP_171815790.1|3243666_3243867_+|hypothetical-protein
MTKQYSQQVLLDCVVEDSESAKQKTQVWQPGSALAQFGFKAAHKNFLNQKFLWKSVNHHSRWGCQN
>NC_019771.1|WP_015214913.1|3243242_3243515_+|YlxR-family-protein
MKPNYRRCISCRRIELKEEFWRIVRVFPSGKVQLDQGMGRSAYICPQTSCLQVAQKKNRLGRSLHGTVPEAVYQELNQRLAQSNTQKNHI
>NC_019771.1|WP_015214912.1|3241874_3243152_+|transcription-termination-factor-NusA
MSMVTLPGLKELIESISRERNLPRLAVQSSIREALLKGYERYRRAQNLERRQFDEEYFDNFEVELDIEGEGFRVLSTKTIVDEVSNTDHQISLEEVQQVAPEAQSGDSVVLDVTPDQGEFGRMAAMQTKQVLAQKLRDQQRQMVQEEFQDLEGTVLQARVLRFERQSVILAVSSGFGQPEVEAELPKREQLPNDNYRANATFKVYLKKVSQGQQRGPQLLVSRADAGLVVYLFANEVPEIEDEVVRIVAVAREANPPSRYVGPRTKIAVDTLDRDVDPVGACIGARGSRIQVVVNELRGEKIDVIRWSPDPATYIANALSPARVDEVRLMDPETRQTHVLVAEDQLSLAIGKEGQNVRLAARLTGWKIDIKDKAKYDYAAEDAKFVAVRAKYQPEDDENEMEELEDENQEELELDHDNFDTGEED
>NC_019771.1|WP_015214911.1|3241293_3241755_+|ribosome-maturation-factor-RimP
MTHPLVPQIIELATPVAEELGLEVVGIVFHTNQRPPVLRVDIRNLQQDTGLNDCERMSRALEASLDAAEIIPDAYVLEVSSPGISRQLVTDREFISFKGFPVTISTSPPYDGQQEWIGHLIRRDETTVYLNQKGRVVEIPRSLVTRVQLDERH
>NC_019771.1|WP_015214910.1|3239663_3241109_+|hypothetical-protein
MMKIKSRKQHNLWFERLMAITATVNLGLVLFDLSYVPWRDFYFRRVPQITQIYDPIKGIETHRDTNKYLETVAALEEQVSQTGLNSPVVMAKLKEINRLSSEMIDSNPFAGAGKSGSLEKIKNRMREHIGQESAKRAFATFWSPGYLSKNGWIQEISFFNQQIRPSMAINYHRKIEENGEFSDAFWLIDLPFVVIFGLELLGRTFYIKRQNPHLSLLEAILWRWYDLFLLIPVWRWLRVLPVIIRLDQAQLIDLHLVRRQIHQGIVANFAEEITEIVVVRVINQVQGSIQRGDLTRWLLQPEKERAYIDINNINEVEAIAGLLLQTIVNQVLPKIQPEINAILSYNIETAFQQIPVYRHLQMLPGVGQAQNQVSEQLVNQITTNLYSALVSAIEDPVAAKLTNELIEKFSKVLGSQIQEKHVITEIQSLLNDFLEEVKINYVQRLSQEDIDQIIEQTRQMRNKASVQTVVHKGVLPEIRDR
>NC_019771.1|WP_015214909.1|3238829_3239408_-|peptidoglycan-binding-protein
MWCNLGKLGTNIALVCVVTVGAVISDTAFAVRQRNYNPEEFRAVLRGLGYNVKVTKIPLTDEETKKAITEFQKGYKLSVDGKVGPKTQAFAANIVQILQGNLNAVLKPNPVLPRDQFYSPRVEELVKEYQKKNQLQETGIADLVLRQKLNEEAKKIISQPVTKPSPTTTPTTKPTPTTKPSPTATPTTKPTS
>NC_019771.1|WP_015214919.1|3251852_3253760_-|hypothetical-protein
MSQITIQCRLVASETTRQQLWQLMAEKNTPLINELLSQIGKHPEFETWRQKGKHPTGIVKELCEPLKTDPRFIGQPARFYTSATASVNYIYESWFALMKRYQSQLDGKLRWLEMFNSDAELVEHSGVSLDTLRATSAEILAQFAPQDTNRDTSNKGKKSKMGKKSQKSDSEGNLSKKLFDAYSSAEDNLTRCAISHLLKNGCKVSNKEENSEKFTQRRRKLEIQIQRLTEKLAARIPKGRDLTDTQWLETLFTATYNVPEDETEAKLWQNSLLRKFSSLPFPVAYETNEDLVWSKNRFGRICLTFPTLREHIFQIYCDSRQLHWFQRFLEDQEIKKNSKNQHSSALFTLRSGRIAWQEGEGKGEPWDIHHLTLYCCVDTRLWTEEGTNLVKEEKAEEIAKTITQTKAKGDLNDKQQAHLKRKNSSLARINNPFPRPSQPLYKGQSHILLGVSLGLEKPATVAVVDGTTGKVLTYRNIKQLLGDNYKLLNRQRQQKHLLSHQRHIAQRIAAPNNFGDSELGEYIDRLLAKEIIAIAQTYQAGSIVLPNLGDMREQIQSEIKAKAEQKSDLVEVQKKYAKQYPNSVHQWSYGRLITNIQSQSKKAGIVIEEGKQQIRASPLEKAKELAINAYQSRKA
>NC_019771.1|WP_015214920.1|3253827_3254256_+|MerR-family-transcriptional-regulator
MQETFFTSKEAAQLTGCTLRQIQYWREKGIVVPIISDTGTGRSIYYSRSNLVELAALVYWLSTGISFDIACETLKRLKAQEPELFISGKGKRFMLLLSAQNESLSLVEFDRKSAIASLDEGKAVIPVWLDIIYQKLASRLAQ
>NC_019771.1|WP_015214921.1|3256939_3258268_+|restriction-endonuclease-subunit-S
MLNKPIWYEEKLGKYAYIKGRIGWRGLKASEYTEDGPYLIAGHHIAAGQVKWSACDHVSMPRYLESREIALEEGDIILTKDGTIGRVAIIDNLPGLATINSTMMLIRVRSPLVPRYVYHYLTGDSFQKLVTDKVSGSSIPHIFQRDMVELTIPFPSKSEQQCIAEILDTIEEAIAHTSSIIAKLKQIKAGLLHDLLTRGLDENGELRDAIAHPQEFKDSPLGKIPKDWEVTVLAQEIDIRHGYAFKGEYFSDDPPGEVLLVPGNFHREGGLYFEKNNIKYYQGEIPESTILQNGDLLTVMTDLSPKTLILGRVVLLDLPFKLLHNQRIGKIVVKSTNRWDKQFLILVMNSDRVRQNIISNATGTTVRHTSPDRITRNIVAKPKLEEQKKISEIIETQDTRIRTEEAYLEKLKLQKKGLMHDLLTGKVRINQVKNNIAIPTTA
>NC_019771.1|WP_015214922.1|3258272_3258908_+|DUF4433-domain-containing-protein
MPIPIYHITHINNLPSILKSGGLMANSRLRQETIKYLDIAHGHIQDRRSITRVPCGAGGTLHNYVPFYFAPRSPMLYAIHRKNVGQYSNGQTPILHLVSSAEAVETAGLSFVGADGHAAMEYTAFFDEIEYLYADGVIDWEIMETNYWADTEEDGDRKRRRQAEFLVHQFFPWRLIEEIGVFNTTIQTQVKEILQKINVQTPVRVYSKWYY
>NC_019771.1|WP_042465015.1|3258962_3260021_+|macro-domain-containing-protein
MMEFKQGNLLEENAEALVNTVNNVGVMGKGIALQFKQAYPENFRQYEKACRAGEVQPGQMFTVSTGSLFNPRYIINFPTKRHWKSKSKIEDIKSGLVALVAEVQKLGITSIAIPPLGCGNGGLNWREVKPLIESSFAQLPNVQVIIFEPSGAPAAEKMQVATKKPNMTRGRALIIRLLEAYGIPGYELTKLEIQKLAYFLQEAGEFLKLPYQKSLYGPYADNLNQVLKHIEGHYIRGYGDGTGRASISVLPQGREAAETFLATELEAQERLEQVSKLIYGFETPYGMELLATVHWVATKHPNPAKDSEEAINLVHEWSERKRKLFKPEHIRKAWQRLGEQNWLTMNSTNMME
>NC_019771.1|WP_015214924.1|3260044_3263344_+|type-I-restriction-endonuclease-subunit-R
MFNEYSQVELPLINQLKLMGWQYIEGDIDVPYLTERQNFREILLTARLHKAIGRINLDDNGLPWLDDSRINTAIGVLERLGTAKLMEANQIATDLLLQGTVAEGDPQRDGGRDQTVRFIDFDHPERNDFLIINQFRVDIPGGKNYIIPDIVLFINGIPLVVIECKSPSSTEPMAEGITQLRRYSNQREEIADDEGVEKLFHYNQFLISTFFHVARVGTIGASYQHYLEWKDTSPVSMAEVAAELGETQLSSQQILVAGMLRPALLMDIVRNFTLFQQSGGKNIKIVARYQQFRAVQEAVRRLQNGKTRSQHGESDQRGGIIWHTQGSGKSLTMVFLVRKLRTLPKLRRFKVVVVTDRVDLQKQLSNTASLTNETVLKATNTEELKTLLRQSSPDLIFATIQKYQQRDEDITEDTSGILKYPSSQGNTTVRKAAEKSSSYNLNPKVVRLVTETEEFPILNDSEDILVLVDEAHRTQASQLHANLMAALPNCARIGFTGTPILEGKRKRTYEIFGEFIDRYTIKESEADGATVPILYEGRTAEAEVADGRSLDQLFEDMFCDRTPEELAAIRAKYATEGNVLEAPKLIAAKAEDMLRHYVETVLPNGFKAQVVASSRLAAVRYQQAFVAAHEKLVAQLESFDPSQPSSNPETEFLTRIYPQLAQIKGLEFASVISSGNNDDPAWKQWSDKSKVEDYINRFKKPLVHPDLNKQDGLAFIIVKSMLLTGFDAPIEQVLYLDRSMQGHELLQAIARVNRTYSRKSCGLVVDYYGVARHLKTALAVYSAEDIQGALISLTDELPKLSDRYQRVLAVFQSRSIPDITDVNSCIDLLRDIKIRAEFVVKLKQFLESLDIVMPRPEALPYIKDAKILGYINKAAANLYRDFQLNIYGAGNKVRQLIDEYIIASGIDPQVPPISIMDADFESAVNSRTSDRAKASEMEHAARYHISKNFQEDPAYYKKLSERLEEILERFQDKWAELVEALRQFTEDLRQGRPADETGLDPRTQAPFLGILVEEIHPGQELLDIELNKLAAITIEMIEHIRQEIRIVDFWRNAHAQNLLRGWIVRFLDDEDVIPFSRQQAVSDRILELAKHLHGKLTII
>NC_019771.1|WP_052334522.1|3263340_3263769_+|DUF45-domain-containing-protein
MSESLVIDDLYFILNRSNKRKTVGITIDRGGELIVNAPYDCPLEIIEQIALEKRFWIYTKLAEKELLSQNHSEKEFINGEGFYYLGRSYRLLLVSAKSPTPLRLYQGRFMLRSNEQSHAREHFIHWYTHILHLTENLSINRK
>NC_019771.1|WP_015214925.1|3265573_3266077_-|TniQ-family-protein
MEVGEINPWLFQVEPYLGESLSHFLGRFRRANDLTTTGLGKAAGVGGAISRWEKFRFNPPPSRQQLEALAKVVGVDADRLEQMLPPAGVGMNLEPIRLCAACYVESPCHRIEWQFKVTQGCQHHHLSLLSECPNCGARFKVPALWVDGWCQRCFLPFGEMIEHQKRI
>NC_019771.1|WP_015212748.1|3266596_3268264_-|IS1634-family-transposase
MKESQVAIQTLDIDHLGIVAGIIDEMELVEEVNKIVGIKTKETLTPGQVVKAMILNGLGFLSAPLYLFGEFFVGKATEHLIGEGVLPEHLNDDKLGRELDKYHQIGTTKIFTAVAIKAAHKFQVEMDSIHLDGTSMSVEGEYKKEIKEIDEIKQETEENKLEIEPEMKAIEIVHGYSRDKRPDLKQFIIDMIVTGDGDIPLYLKVDSGNVDDKSVFVERLKEFKKQWTFEGISVADSALYTAENLAAMRELKWITRVPLSIKEAKNKIVDIKEAEWKDSQISGYKIAAKESEYAGIKQRWIIVESEIRKKSSIQQVEKQVKKQEAKAKAALSKLSRQEFACQPDAKIVIEKLSKSWKYHQIKEIEYIEKLEYKTAGRPSKLTEPSQIKYQIKGQIETREEVIETEKINAGRFILATNVLDRNELSDEKVLEEYKAQQSNERGFRFLKDPLFFTSSVFVKTPERVEAIAMIMGLCLLVYNLAQRKLRQELAKFDDGIRNQVKKITNKPTMRWVFQMFQAVHLVIINGQKQMSNLTEEREKIVRYLGKSCSKYYLIT
>NC_019771.1|WP_150111014.1|3269022_3270726_-|Mu-transposase-C-terminal-domain-containing-protein
MRNETPLTPGNLGDESSIGKETQVLVSELSGEAKLKMEVIQSLLEAGDRTTYAQRLKEAAVKLGKSVRTVRRLIDKWEEEGLVGLTQTERVDKGKHRVDENWQEFILKTYKEGNKGGKRMSRQQVAVRVKVRADDLGVKPPSHMTVYRILEPVIEKQEKAKSIRSPGWRGSRLSVKTRDGKDLQVEYSNQVWQCDHTRADVLLVDKHGEILGRPWLTTVIDSYSRCIVGINLGYDAPSSQVVALALRHAILPKQYGQEYELYEEWGTYGKPEHFYTDGGKDFRSNHLQQIGVQLGFACHLRDRPSEGGIVERPFKTFNTQLFSTLQGYTGSNVQERPEEAEKEACLTLRELEQRLVAYIVNTYNQREDARMGDQTRFQRWDSGLIVAPEVISERDLDICLMKQSRRMIQRGGYLQFENLMYKGEHLAGYAGESVVLRYDPRDITTILVYSHKGHKEEFLARAYAQDLETEELSLDEAKAMIRRIREAGKTISNRSMLAEVRDRETFVKQKKTKKERQKEEQAVVQKTKKPVPVEPVEEIEVAFVESSQETDMPEVFDYEQMREDYGW

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_019771_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_14

3336972-3337087

Orphan

A:N

Consensus_repeat	Method
TAGAGGCAGAGCCTCTGTGGTAGCATTCCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019771_14

>merge|NC_019771|14|3336972-3337087|CRISPRCasFinder
TAGAGGCAGAGCCTCTGTGGTAGCATTCCTGGTCAGAGACTAGGAACGAGATAATGGTACTTACAACGAAGTGCTATCAATGATAGTAGAGGCAGAGCCTCTGTGGTAACATTCCT

>NC_019771|14|14|3336972-3337087|CRISPRCasFinder
TAGAGGCAGAGCCTCTGTGGTAGCATTCCT	GGTCAGAGACTAGGAACGAGATAATGGTACTTACAACGAAGTGCTATCAATGATAG
TAGAGGCAGAGCCTCTGTGGTAACATTCCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015214983.1\|3341093_3342260_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_171815791.1\|3345262_3345775_+\|WD40-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|238121
NC_019771.1\|WP_015214978.1\|3337166_3337931_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
NC_019771.1\|WP_015214969.1\|3329689_3332236_+\|NACHT-domain-containing-protein	unknown	unknown	gnl\|CDD\|227922
NC_019771.1\|WP_015214985.1\|3343259_3344285_+\|multicopper-oxidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|259910
NC_019771.1\|WP_015214981.1\|3340195_3340609_-\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|366837
NC_019771.1\|WP_015214968.1\|3329488_3329686_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015214986.1\|3344531_3345062_+\|ferric-reductase-like-transmembrane-domain-containing-protein	unknown	unknown	gnl\|CDD\|225338
NC_019771.1\|WP_015214977.1\|3336270_3336744_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015214975.1\|3334160_3335324_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376268
NC_019771.1\|WP_015214974.1\|3333670_3334003_+\|DUF5615-family-PIN-like-protein	unknown	unknown	gnl\|CDD\|375906
NC_019771.1\|WP_015214972.1\|3333031_3333328_+\|transcription-regulator-with-HTH-domain	unknown	unknown	gnl\|CDD\|227786
NC_019771.1\|WP_015214976.1\|3335476_3336133_-\|DUF1361-domain-containing-protein	unknown	unknown	gnl\|CDD\|226780
NC_019771.1\|WP_015214980.1\|3338634_3339558_-\|PDGLE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376649
NC_019771.1\|WP_015214971.1\|3332723_3333017_+\|type-II-toxin-antitoxin-system-HigB-family-toxin	unknown	unknown	gnl\|CDD\|227025
NC_019771.1\|WP_015214973.1\|3333449_3333674_+\|DUF433-domain-containing-protein	unknown	unknown	gnl\|CDD\|225291
NC_019771.1\|WP_015214970.1\|3332271_3332523_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015214982.1\|3340614_3340977_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015214979.1\|3337973_3338642_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NC_019771.1\|WP_015214984.1\|3342777_3342969_-\|CbtB-domain-containing-protein	unknown	unknown	gnl\|CDD\|370526

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_171815791.1\|3345262_3345775_+\|WD40-repeat-domain-containing-protein	gnl\|CDD\|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	2.28933e-52
NC_019771.1\|WP_015214978.1\|3337166_3337931_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.32579e-84
NC_019771.1\|WP_015214969.1\|3329689_3332236_+\|NACHT-domain-containing-protein	gnl\|CDD\|227922	COG5635, COG5635, Predicted NTPase (NACHT family) [Signal transduction mechanisms].	9.97367e-65
NC_019771.1\|WP_015214985.1\|3343259_3344285_+\|multicopper-oxidase-domain-containing-protein	gnl\|CDD\|259910	cd11024, CuRO_1_2DMCO_NIR_like, The cupredoxin domain 1 of a two-domain laccase related to nitrite reductase. The two-domain laccase (small laccase) in this family differs significantly from all laccases. It resembles the two domain nitrite reductase in both sequence and structure. It consists of two cupredoxin domains and forms trimers and hence resembles the quaternary structure of nitrite reductases more than that of large laccases. There are three trinuclear copper clusters in the enzyme localized between domains 1 and 2 of each pair of neighbor chains. Three copper ions of type 1 lie close to one another near the surface of the central part of the trimer, and, effectively, a trimeric substrate binding site is formed in their vicinity. Laccase is a blue multi-copper enzyme that catalyzes the oxidation of a variety of organic substrates coupled to the reduction of molecular oxygen to water. It displays broad substrate specificity, catalyzing the oxidation of a wide variety of aromatic, notably phenolic, and inorganic substances. Laccase has been implicated in a wide spectrum of biological activities.	8.49468e-58
NC_019771.1\|WP_015214981.1\|3340195_3340609_-\|HNH-endonuclease	gnl\|CDD\|366837	pfam01844, HNH, HNH endonuclease. His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity.	1.4101e-09
NC_019771.1\|WP_015214986.1\|3344531_3345062_+\|ferric-reductase-like-transmembrane-domain-containing-protein	gnl\|CDD\|225338	COG2717, COG2717, Predicted membrane protein [Function unknown].	1.02377e-09
NC_019771.1\|WP_015214975.1\|3334160_3335324_-\|hypothetical-protein	gnl\|CDD\|376268	pfam18849, baeRF_family7, Bacterial archaeo-eukaryotic release factor family 7. Bacterial family of the archaeo-eukaryotic release factor superfamily. Likely to play roles in biological conflicts or regulation under stress conditions at the ribosome. Consistent with this, many members of the family associate on the genome with HPF-like ribosome hibernation factor.	6.39136e-48
NC_019771.1\|WP_015214974.1\|3333670_3334003_+\|DUF5615-family-PIN-like-protein	gnl\|CDD\|375906	pfam18480, DUF5615, Domain of unknown function (DUF5615). This is a domain of unknown function found in potential toxin-antitoxin system component.	3.63589e-33
NC_019771.1\|WP_015214972.1\|3333031_3333328_+\|transcription-regulator-with-HTH-domain	gnl\|CDD\|227786	COG5499, COG5499, Predicted transcription regulator containing HTH domain [Transcription].	1.18184e-17
NC_019771.1\|WP_015214976.1\|3335476_3336133_-\|DUF1361-domain-containing-protein	gnl\|CDD\|226780	COG4330, COG4330, Predicted membrane protein [Function unknown].	3.55161e-61
NC_019771.1\|WP_015214980.1\|3338634_3339558_-\|PDGLE-domain-containing-protein	gnl\|CDD\|376649	pfam01891, CbiM, Cobalt uptake substrate-specific transmembrane region. This family of proteins forms part of the cobalt-transport complex in prokaryotes, CbiMNQO. CbiMNQO and NikMNQO are the most widespread groups of microbial transporters for cobalt and nickel ions and are unusual uptake systems as they consist of eg two transmembrane components (CbiM and CbiQ), a small membrane-bound component (CbiN) and an ATP-binding protein (CbiO) but no extracytoplasmic solute-binding protein. Similar components constitute the nickel transporters with some variability in the small membrane-bound component, either NikN or NikL, which are not similar to CbiN at the sequence level. CbiM is the substrate-specific component of the complex and is a seven-transmembrane protein. The CbiMNQO and NikMNQO systems form part of the coenzyme B12 biosynthesis pathway. The NikM protein is pfam10670.	1.37329e-50
NC_019771.1\|WP_015214971.1\|3332723_3333017_+\|type-II-toxin-antitoxin-system-HigB-family-toxin	gnl\|CDD\|227025	COG4680, COG4680, Uncharacterized protein conserved in bacteria [Function unknown].	4.13078e-43
NC_019771.1\|WP_015214973.1\|3333449_3333674_+\|DUF433-domain-containing-protein	gnl\|CDD\|225291	COG2442, COG2442, Uncharacterized conserved protein [Function unknown].	2.5063e-27
NC_019771.1\|WP_015214979.1\|3337973_3338642_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	1.00937e-16
NC_019771.1\|WP_015214984.1\|3342777_3342969_-\|CbtB-domain-containing-protein	gnl\|CDD\|370526	pfam09489, CbtB, Probable cobalt transporter subunit (CbtB). This entry represents a family of proteins which have been proposed to act as cobalt transporters acting in concert with vitamin B12 biosynthesis systems. Evidence for this assignment includes 1) prediction of a single transmembrane segment and a C-terminal histidine-rich motif likely to be a metal-binding site, 2) positional gene linkage with known B12 biosynthesis genes, 3) upstream proximity of B12 transcriptional regulatory sites, 4) the absence of other known cobalt import systems and 5) the obligate co-localization with a protein (CbtA) predicted to have five additional transmembrane segments.	0.000241278

>NC_019771.1|WP_015214977.1|3336270_3336744_-|hypothetical-protein
MFFVRKNTVITSLSLSIALFLTSCNETKVSQCQRLIKVVNQGTSLIDNNKGKQVTTSLQLSRDLQTVTKSIQELKLADPKLQEFQSNFAKVFDNLSQGFSTAAKALSTAKTSEASSDGRQKIQKARTDIDSTLTVAATTAGKQSDTFGNQLNEYCSQ
>NC_019771.1|WP_015214976.1|3335476_3336133_-|DUF1361-domain-containing-protein
MKSELIELIAIVIQVLQSNMRWMTWNLFLAFIPLALSIWLFRTKIGRSWVWWLGFLAFYAFLPNAPYLLTDVIHLIDDIRRIPSVWIITLILIPVYLVVILGGFEAYVISLINLGHYLHRIGKSKWIFGVELITHALSAIGIYWGRFLRFNSWDFITQPDAILTKGVEELFGKQPLVIITVTFVILFGLYWIMKRVTLGLVNKDVNSPPANPHISKAG
>NC_019771.1|WP_015214975.1|3334160_3335324_-|hypothetical-protein
MTLLSIDELKTLVANPETPCVSLYMPMQKAGPEIRQNPIRFKNLIREAEERLDTGIRHTEALNLLKPAMELDRVDFWEHQDQGLVILISPNLFRYYCLPIEFPELVVVGEQFHLKPLLHLINNDGSFYVLALSQKDVKLFAGTAHSFHEVQINTIPHRLAETLLEDELQKGVQHGIGTPRGATASAQHPGSVHGQGSSDREKHEEDILQFFYAIDTALHEKLREEKAPLVLAGVEYLFPIYQEANTYPHLVEESINGNPEVINLEQLHDEAWRIVAPSFQEEKKAAIELYQQFAGEDNGKATSDIKEIIPAAYYQRVDSLFVSVDDQTWGKFDSETSTVDLHAEPEPDDEDMLDCAAVHTLLNGGRVYTLESGEMPHGATAAAIFRY
>NC_019771.1|WP_015214974.1|3333670_3334003_+|DUF5615-family-PIN-like-protein
MKLLFDHNLSPRLVDKLAAIYPNSQHVFLLGLDQADDRILWEYAKQNEFIVVTRDADFNELSILRGYPPKVIWVRRGNCSTNQIEEILRVHLADIQAFAKNSDLGVLTLY
>NC_019771.1|WP_015214973.1|3333449_3333674_+|DUF433-domain-containing-protein
MQYQNIITIEPGKRGGKPCIRGMRITVYDVLSYLASGMTYEEILNDFPYLTQEDILACLSYAADRERQMLMVQA
>NC_019771.1|WP_015214972.1|3333031_3333328_+|transcription-regulator-with-HTH-domain
MNLKPIRTESDYQQALKEIEQIFDAEPHTPEYEKLDILTTLVEVYEQQNYPIDTPSPIAAILYYLESRNQGIYNFIENLKHHGVSEEIINIALNEMSH
>NC_019771.1|WP_015214971.1|3332723_3333017_+|type-II-toxin-antitoxin-system-HigB-family-toxin
MRIIARSTLREYWQKHPDTEQPLKAWFDDASRASWQSPSDIKEVYANASIIANNRVVFNIKGNNYRLIIHIRYEIGIIFIRFIGTHQEYDKIDATIV
>NC_019771.1|WP_015214970.1|3332271_3332523_-|hypothetical-protein
MSNHSGSYMLNEVITILRRENCFDHLDQEKKQNLIEEIVRLARYEDDCNSGEILEGHTDYFQICYCCLAKTNDLESGLCVKCR
>NC_019771.1|WP_015214969.1|3329689_3332236_+|NACHT-domain-containing-protein
MDSEELRGLIARKEDAKLDFKIESKVINGIKDDKEWDEFLKDIISIANGNIGTATETGYLIIGAGDKLKLDGTRDLKDVGVVTIQEKQILDKLKSACEPRLPEIKCDVVSLDGKRLFIISIPPTPYLYTLTKYLQTPKKGYSPNTVLIRRKDGEEIYEADDHEKDILRKEKKNITSLNSIISIDCLVEEVRNKCCDKIQHLYSKIKLLNLQSIDVDQLYVDVYLLKKISSETLATIDGLVKNSNLQDDFDRFGLGQRRGRIDGFEVAKKRSKLMILGKPGSGKTTFLRHLAVACCQGEFKSENIPVFIELRSITNASHFNLFDEIHKEFDLTNQEQTKQILKQGKVLIFLDGLDEVSTESRRDVQKQIDEFSRNSLYYKNHLIITCRTQTTEYTLQNFDYVEVADFHPAQVEKFSRNWFTTLANTHQEGEEITAKFLEKLRLPENKQIAELAVTPILLSLTCWIFGESKDLPPKRSQLYQRGINLLLKEWDKKRDIQRDLGSERYRNLSLGDKQKLLSYIAYLKFNQEQYALFKESEIQKYISEYLKDISNNDIQSVVKTIEAQHGLLIQRAQDIDSEGIYSFSHLTFQEYFTAKYIVENNQIEQLVKEHLTDTRWREVFLLTAELMGDNAGNFLSLMQAESQKYINTPKLQNLLHWADEITSGTAGNIKPVGKRAIAIAIAVAIGYAEANIIAHAANAIGIANAIGITNIPIYAYTNAIGIAYYSPNVNTINKDIETMYEIEKLKIFNNEEFTKLAVNLEKLKSEIPNDEKQQEKFNKFAEELPTTLLNAFNLPREMIYSFMAELETLNHKYLYVNKLIIDCKRAAIDEASPPWWQEIEERMLKPTL
>NC_019771.1|WP_015214968.1|3329488_3329686_+|hypothetical-protein
MTKLLEQAIAQIKQLPETEQDIIARLILKALETNLVEENLSIIDESDTWTEEDKLDITSFSLQLI
>NC_019771.1|WP_015214978.1|3337166_3337931_-|ABC-transporter-ATP-binding-protein
MTSLTSHPQTSISHPHTAVVEVKNLVYAYSHQQPVLREISFKLNSSDRVALMGATGSGKSTLLENLIGLKHPQSGSIFINGIPVEPKTLPQIRKQIGFTFQDANDQLFMPTILEDVTFGPRNYGVSPATAIDKALQLLADFGLEEYAHRSAHELSGGQRRLAALASILALDPAILILDEPTTGLDPSWRRHLAQVLLKLPVQVMLIASHDLHWLGKVTQRALVLSAGQIQIDSHIQPLLQDGKTLDQLGLPVDW
>NC_019771.1|WP_015214979.1|3337973_3338642_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MLKLSLPLRLQLSLVIVIGAALLKYHAWSNLLVYGAIALLWMWLLRVPIRKLGGLLGTELIFLSLMALPLGWERASFLLMRSLICLITMNSFLLTLPPHSFGIALKGLPIPAPLKENLLLSGQYLEILLSEVGRMQRSAQLRGLNGAAGWLRYASTAMIGALYLRTLDRAERVYAAMVTRGYNGQLPIDSTLRPKERLTILTAGAIASCITLSSYFQSFAHN
>NC_019771.1|WP_015214980.1|3338634_3339558_-|PDGLE-domain-containing-protein
MHIPDGFISVPVAGATSLASAAALFVAFGRSEEAYGIRRAPILGLTTAFIFAAQMINFPVAGGTSGHLCGGALAAIILGSPWAGMLCIATVLIIQAVLFADGGITALGANIFNLGVIGVWVAWGLTQTLQRLLGGSKGRLPLAAGIAAGVSVVVSAIACAIQLALSGTASANVVLPTMTGVHILIGIGEGLITGGVLTYLATARPDLLPGEEEKFKGWLVPVVSIILVAGVLSLFASAWPDGLESVAENLGFINLAEEVRVEVPTPFADYGIAGLEQIGTSIAGLIGAAVCFAVAFGIAKVMKPKNA
>NC_019771.1|WP_015214981.1|3340195_3340609_-|HNH-endonuclease
MARFYIPVEIERRVRKDAQNRCGYCLSPQRLVMARLEIEHIIPIAKSGSHHESNLWLVCPICNRYKSDKVIGIDPETGEIVKLFNPRTQVWCEHFFWTEDGLQIVGKTPTGRATVKALHLSDDADALEVRSYWVLAG
>NC_019771.1|WP_015214982.1|3340614_3340977_-|hypothetical-protein
MSETVTLKLPERLVQKAKEIAAFSHRHLEDVLLEWIDRASNELPVESLPDEQILSLCDLQMETQQQEVFSDLLARQQEGQLTDIENSQLDELMQVYRHGLVRKAKALKVAVERGLIATIT
>NC_019771.1|WP_015214983.1|3341093_3342260_-|hypothetical-protein
MKKYRLFGFISAVCITLSILYSVVGVSQTTKPHVQLSTNPSLERILPFEAGTEKEQSPVKMTFQAMDAASKPIGNALINLQILTPQRNPLLTTDFPIVEGTKLLEIEAEVPDGKLEFQQIFPIRGHYQLKVNVSPLVANAFVPYQENLDLNVRENPVKYKYFAVTVAILLSLGLLGGWVIGGQQELQEGEIAPQSVRLLLSALTVVAIVTLLFINITAEVAEAHGSGHSHNKETIAPSVEKSQGMEVSLEGDKTATVGKLANLGVQVKDSTTGKPIQDARLLVKAIALEDNLTVFAYNGVTNKEGKLRWMSQLFDGAPHKIEVEVMPSADSQQQSPPIKVAQEVEVEAIAPPIYIRLIGLFYFTAIVGIGMAIGLLIQQRKGLQVREN
>NC_019771.1|WP_015214984.1|3342777_3342969_-|CbtB-domain-containing-protein
MTTFSFTSVLQKTAGATLSKPVQVTLYMMLSSLIIWTVLFSNYPPAHNTAHSLRHHALGVSCH
>NC_019771.1|WP_015214985.1|3343259_3344285_+|multicopper-oxidase-domain-containing-protein
MFDNFTLSKDKLWSRRQLLKLGLAGAGVTGAATIWQMLNRSNYANVRIPPMEMEASKGATNPMQVLRNFDYGTLKQENGRTIREFQLTAGTSTIQLNSAVSYNIWDLNGRIPGPTLRAKQGERVRVLFLNQAGHSHSLHFHGVHPSEMDGVRPISNNKATIYEFDAEPYGVHLYHCHVAPVTRHIAKGLYGMFIIDPPQPRPPADEIVLIMSGYDVNDDNRNEYYAFNGVPHHYMHHPIPIYQNQLIRIYVLNIIEFDPAVTFHLHANFFNVYRSGMTMIPSEKTDVLTMGVAERHILEFAFRYPGKYMFHPHQDVVAENGCMGQFEVIAAKDVKTPEKNT
>NC_019771.1|WP_015214986.1|3344531_3345062_+|ferric-reductase-like-transmembrane-domain-containing-protein
MLINASISSANLLGFISLLSYILTLLPSSIRAVFPQIKKAKITICLWKYRRQLGVVTFVFALVHTVLIVNKRNLDLFDIQTYEISLEGTLTLIIFVLLAFTSNDWSVKKMKQNWRRLHKLTYIAMFLLLWHIQEKMSGQWNILTPIELILITVTIGLFCRRRWLEYTKEYNQKQIS
>NC_019771.1|WP_171815791.1|3345262_3345775_+|WD40-repeat-domain-containing-protein
MYVYSLAISPDGKTIVNGNLNKDIDVWNLQTGKIIHQLCGHKNSVNSVAISPNNQIIASGSWDKTIKIWSLKTGKLIQTLSGHTDDVKAVAISPNNQIIASGSWDKTIKIWSLKTGDTLINLPQSDGVRTVAFSPDGKILAGGGEGGKIMLWYLTTGKLKTSLAAHRKPI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_019771_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_15

3906229-3906312

Orphan

A:N

Consensus_repeat	Method
GGATTTTAGAGAAAGCGATTTTAGATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019771_15

>merge|NC_019771|15|3906229-3906312|CRISPRCasFinder
GGATTTTAGAGAAAGCGATTTTAGATTGACTGTACTCACTCTTGGGTTACAGCTTGGGGATTTTAGAGAAAGCTATTTTAGATT

>NC_019771|15|15|3906229-3906312|CRISPRCasFinder
GGATTTTAGAGAAAGCGATTTTAGATT	GACTGTACTCACTCTTGGGTTACAGCTTGG
GGATTTTAGAGAAAGCTATTTTAGATT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015215441.1\|3894827_3895229_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|366837
NC_019771.1\|WP_015215454.1\|3913193_3914405_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340831
NC_019771.1\|WP_015215439.1\|3891742_3894322_+\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
NC_019771.1\|WP_015215450.1\|3907107_3907881_-\|hydroxyacylglutathione-hydrolase	unknown	unknown	gnl\|CDD\|274569
NC_019771.1\|WP_015215446.1\|3902228_3902552_+\|phasin-family-protein	unknown	unknown	gnl\|CDD\|226447
NC_019771.1\|WP_015215449.1\|3906443_3906902_-\|50S-ribosomal-protein-L9	unknown	unknown	gnl\|CDD\|234659
NC_019771.1\|WP_081593697.1\|3908175_3908691_+\|alpha-1,2-fucosyltransferase	unknown	unknown	gnl\|CDD\|211389
NC_019771.1\|WP_015215453.1\|3910939_3913189_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_019771.1\|WP_015215452.1\|3909677_3910850_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340831
NC_019771.1\|WP_015215445.1\|3898537_3901648_-\|DUF4114-domain-containing-protein	unknown	unknown	gnl\|CDD\|273296
NC_019771.1\|WP_015215440.1\|3894468_3894831_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015215451.1\|3908717_3909560_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|133037
NC_019771.1\|WP_015215442.1\|3895301_3896474_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|379114
NC_019771.1\|WP_015215456.1\|3915419_3916418_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015215457.1\|3916429_3917359_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015215443.1\|3896491_3897445_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_042466049.1\|3902634_3903159_+\|FKBP-type-peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|223619
NC_019771.1\|WP_150111100.1\|3897619_3898306_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NC_019771.1\|WP_015215448.1\|3903297_3906138_-\|replicative-DNA-helicase	unknown	unknown	gnl\|CDD\|273206
NC_019771.1\|WP_015215455.1\|3914429_3915383_+\|glycosyl-transferase	unknown	unknown	gnl\|CDD\|366335

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015215441.1\|3894827_3895229_+\|HNH-endonuclease	gnl\|CDD\|366837	pfam01844, HNH, HNH endonuclease. His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity.	1.56602e-11
NC_019771.1\|WP_015215454.1\|3913193_3914405_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	5.44435e-26
NC_019771.1\|WP_015215439.1\|3891742_3894322_+\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NC_019771.1\|WP_015215450.1\|3907107_3907881_-\|hydroxyacylglutathione-hydrolase	gnl\|CDD\|274569	TIGR03413, GSH_gloB, hydroxyacylglutathione hydrolase. Members of this protein family are hydroxyacylglutathione hydrolase, a detoxification enzyme known as glyoxalase II. It follows lactoylglutathione lyase, or glyoxalase I, and acts to remove the toxic metabolite methylglyoxal and related compounds. This protein belongs to the broader metallo-beta-lactamase family (pfam00753). [Cellular processes, Detoxification].	2.49838e-138
NC_019771.1\|WP_015215446.1\|3902228_3902552_+\|phasin-family-protein	gnl\|CDD\|226447	COG3937, COG3937, Uncharacterized conserved protein [Function unknown].	1.15576e-32
NC_019771.1\|WP_015215449.1\|3906443_3906902_-\|50S-ribosomal-protein-L9	gnl\|CDD\|234659	PRK00137, rplI, 50S ribosomal protein L9; Reviewed.	4.47713e-55
NC_019771.1\|WP_015215451.1\|3908717_3909560_+\|hypothetical-protein	gnl\|CDD\|133037	cd04194, GT8_A4GalT_like, A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.	0.000178965
NC_019771.1\|WP_015215453.1\|3910939_3913189_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	7.58284e-143
NC_019771.1\|WP_015215445.1\|3898537_3901648_-\|DUF4114-domain-containing-protein	gnl\|CDD\|273296	TIGR00845, Sodium/calcium_exchanger_1, sodium/calcium exchanger 1. The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other].	2.18356e-12
NC_019771.1\|WP_042466049.1\|3902634_3903159_+\|FKBP-type-peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|223619	COG0545, FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones].	7.28037e-59
NC_019771.1\|WP_015215452.1\|3909677_3910850_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	7.03448e-42
NC_019771.1\|WP_015215442.1\|3895301_3896474_+\|ATP-binding-protein	gnl\|CDD\|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	3.5055e-12
NC_019771.1\|WP_081593697.1\|3908175_3908691_+\|alpha-1,2-fucosyltransferase	gnl\|CDD\|211389	cd11548, NodZ_like, Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.	6.58312e-08
NC_019771.1\|WP_150111100.1\|3897619_3898306_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	2.32146e-07
NC_019771.1\|WP_015215448.1\|3903297_3906138_-\|replicative-DNA-helicase	gnl\|CDD\|273206	TIGR00665, DnaB, replicative DNA helicase. This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair].	3.29492e-139
NC_019771.1\|WP_015215455.1\|3914429_3915383_+\|glycosyl-transferase	gnl\|CDD\|366335	pfam00852, Glyco_transf_10, Glycosyltransferase family 10 (fucosyltransferase) C-term. This is the C-terminal domain of a family of fucosyltransferases. This enzyme transfers fucose from GDP-Fucose to GlcNAc in an alpha1,3 linkage. This family is known as glycosyltransferase family 10. The C-terminal domain is the likely binding-region for ADP (manuscript in publication).	8.67017e-09

>NC_019771.1|WP_015215448.1|3903297_3906138_-|replicative-DNA-helicase
MAEELSFQGDGSNRLPPQNIEAEEAILGGILLDPEAIGRIRDRLAPEAFYISAHRDIYQAAIALHAQNKPTDLLSLTSWLTDNDKLTRIGGRNKLATLVDRTVSAVNIDALAGLVTEKYLRRQLIKAGNEVVHLGYETETELPIVLDQAEQKVFGVTQERPQSGLVHISDTLINAFQEIETRHQGIALPGIPCGFYDLDAMTSGFQRSDLIIIAGRPSMGKCLSYDSEIVLADGQITTIEELYNQRQGSLLTLNNDWKFTFTQPSAFVDDGIKPVFRVTTRLGRSIETTITHPYLTINGWQRLENLKIGDKIAVPRKIDVFGKETLRECEVKLLGYLIGDGGLTNSTPRFTNSNPLLQADFSQAITDFGGLSVRCEDSQGQRTPSLCVRGNLEFIATQRELFAESLKTAISSRSLSAKQLSHELGVSPSLLCMWQKGECVPNLNTFQLLCKTLNMELEEFAPHGFTSISQSSKNVLTIWLEKLGLWGKDAHAKTIPKIIFKLEKSQISLFLNRLFATDGWATLLASGQSQLGYATVSEKLARQIQHLLLRFGIIATLKKRSVKYNNTRRPAWQLDITDALSIKTFISEIGIFGKEEALAKVTAAISTKRYQTNRDLIPVDIWEQIAVAKGSETWNSLAYRVGIKGYSNMHVGKRSLRRERLWILATALDNLSLQQLASSDIYWDEIVAIDAVGNKQVYDLTIPETHNFVANDVCVHNTAFCLNLAHNIAAGYKLPVAVFSLEMSKEQLVQRLLASEAGIESGYLRSGRISQTQWEPLSRAIGMLSEMPIFIDDTANITVTQMRSQARRLQAEQNTELGLIVIDYLQLMEGGGDNRVQELSRITRSLKGLARELSVPVIALSQLSRGVEARTNKRPMLSDLRESGSIEQDADLVIMLYRDEYYSPDTPDRGITEVIVAKHRNGPTGTIKLLFDPQFTKFKNLARPNY
>NC_019771.1|WP_042466049.1|3902634_3903159_+|FKBP-type-peptidyl-prolyl-cis-trans-isomerase
MKGILLSVVFMLVCVVALVLAQVGGKQETDIAAKLTQTPSAATVVIAENNTLIASKIMSDEKVVTTPSGLKYVELAQGSGATPEKGKTVVVHYTGTLEDGTKFDSSRDRGQPFSFKIGIGQVIKGWDEGLSTMKVGDRRKLIIPSELGYGASGAGNVIPPYSTLIFDVELLEIK
>NC_019771.1|WP_015215446.1|3902228_3902552_+|phasin-family-protein
MDSNNWLEQLMMLGIGTTSLVADKLRQVSDELVKDGKLNPEQAKAVMDDIVQQLKSDQGNWEVQMQRQMRNMMQDLGVARQSEVDELRGRIDRLERQVRDLENKLWR
>NC_019771.1|WP_015215445.1|3898537_3901648_-|DUF4114-domain-containing-protein
MIINGTANNDELYAQQGDEVFGFEGEDTLYAEGILGNNTLNGGEGNDFLSVVEGENNTLNGGNGNDRLFVVEGNNNTLNGDAGDDELYVIEGSFNTLKGGIGNDFLKTSSLTGNNTLEGGEGHDTLIGYLSSDRLFGDAGDDSLYAGKQGSQMTGGAGLDRFYFGNGSVPDVPAEVLDFTTSVDKVVIAGIPQVQNFEDIILVQDGNDTIVKALIDGSERSFGILKNVNKDTLTAEDFDFIVPVFSITGASAVEGNAITFTITRTGDILIDQTVTVSTSIGTASSSDFISKTQEFTFTQGETHKTFTVDTIQDALFEGNETFTVTLSNSTNGSVISSTNGTAQGTITNDDAAPVFAIASASALEGNAIAFTITRTGDAQASQSVTVSTSIATGDTASTSDFTTNTQTLTFAQGETQKTFTVQTNEDQLFEGNETFTVTLSNSTNGAVISSTNGTAQGTITNDDAVAVFAIASASALEGNAIAFTITRTGDAQASQSVTVSTSIATGDTASTSDFTTNTQTLTFAQGETQKTFTVQTNEDQLFEGNETFTVTLSNSTNGAVISSTNGTAQGTITNDDAVAVFAIASASALEGNAISFTITRTGDAQASQNITVSTSVATGDTASTSDFTAKTETLTFAVGETQKTFTVATTEDFRVEENETFTVNLSNATNSATISSTNGTAKGTINDDDISLAVITNNSIFNIKGTGNTVRLKATLIERNSSFVNELGVFIVDDADGRINGLAPGQQGYNEAALERAKSQGKSIFSAITNIPNGFNTVDLIRLLEFDSGNYLKFFLVKDGTIDSFRAGLTQTTNILFADSSTQIITQEEDSFTISWKESTTITEFNSLKVKIESTDESLTLGTALQGENQAELIDLTDITGLVKADFSVFREAAYNNEVYFYEIDNAQGQISGLQATSANRANYLQAAINNLIKDAETGETIKFAVSNQGQFTDSAMIAGGSILAPMIIINGTLSQLTDNNTSNDPQVYFPYLGVNSDGIDHIRLLADNTFGFEDLPNGGDFDYNDLIIKFDFNIV
>NC_019771.1|WP_150111100.1|3897619_3898306_+|CPBP-family-intramembrane-metalloprotease
MQLTQRRRSLFALLISVPFTSIGAVMSLLIAPGIIGQTILVMCQLWLLFLPVAWLLWVERKPLKISKPTRYDWLIGLALGLLMFGIILATYWFFLRDWINVNDVRNKLQKVGNINQLFFKLGGAYFILINALIEEYFWRWFVYSRCEELVSGRTAVFLAALFFTIHHTIGLAVFTDWRMVLLGSLFVFVAGVVWSECYRRYRSIWSNYFSHLIADLALHIVAWQIFFG
>NC_019771.1|WP_015215443.1|3896491_3897445_+|hypothetical-protein
MSFNKQELKEHCLKIIQDSRIRNKIVILCEGLIPPKVEGRRSPQLYKQMEQMPDANFYHACVPTWWKQYRPIFFNCGDRNDVLNTFFGILDLHNADNSKSFLSPDELFAVVDLDVQLANIKEDYIFENTEDIFYNLYHQGNINDSNINHHRIWITGLIHKEAYFLKPDIQEVFDNQYTIYPLYKQTPVNLEKIYLDMVNDMNNDADLHNHWSRVIKRISHLSNFDDMEIDKFQYSWQEEYENNQDLDYKNKLINAVLMLVKSKEYWRQISPDDNWNHSPYKFREQLSLKIGTFYSKQDCIVENHIPFFFKSLYELIE
>NC_019771.1|WP_015215442.1|3895301_3896474_+|ATP-binding-protein
MHIQRIQVPDFRALKNVDITFEKEFTPRIFPLGSQNGGGKSTLLQLIFVLLHCSGNPDRVEFIQNLLDGFQVNHESGQRTLAIINIWDGNKTVTLDFFICSQSYILNLLNGEYIESSIVNLFNQDNEIKLMSFYEEKSDKHITLSFICNFQSAQNEALFFQFDGIDIDEVNKFVIELSNKIFLTAHISQIFLLLQPDNRKSLFKTQANNQTNYYQQIKAANSKLPGFFTYDFLSIDILLEAFKKARDEDFKQAVEQRGNYGNNYVKLLDELNNLLSNKKINVQPDLSGINFKIDGDDTELYPEDLSHGELKRLCIYMWLKHNKIEDAIVLMDELEISFHPDWQYQIVRDLEEWGATNQYILATHSYELCNAVTPAHVKELDPKLQARTIQ
>NC_019771.1|WP_015215441.1|3894827_3895229_+|HNH-endonuclease
MNPFYHLVADRAFHRCEYCHAPELVFNFPFELEHIVPTSRGGANVESNLALACRSCNLRKGSRLSEIDPESNTEVRLFNPREDRWEDHFQVNSETGLIIGITPIGRVTVNSLDLNSQSQVIARQLWIRLGLFP
>NC_019771.1|WP_015215440.1|3894468_3894831_+|hypothetical-protein
MTTVAIVPTSNASGEKSYCAISGDKQSIGKTAGQALDALTIQLGEVEFRALLIIDNFRPDQFFTNEQKQRLSELMSMWRTARDQGQTLPPEIQIELDNLVNAELNAATARTASLAQQLSQ
>NC_019771.1|WP_015215439.1|3891742_3894322_+|leucine--tRNA-ligase
MESPQKTLYHPAAIEEKWQKTWLELGLDKTPQDQNKPKFYALSMFPYPSGSLHMGHVRNYTITDVIARLKRMQGYRVLHPMGWDAFGLPAENAAIDRGVPPAKWTYQNIAQMRQQLQRLGLSLDWECEVATCSPDYYKWTQWIFLQFLQAGLAYQREAAVNWDPIDQTVLANEQVDNEGRSWRSGAIVERKLLRQWFFKITDYAEELLNDLDKLTGWPERVKLMQANWIGKSTGAYLEFPIVGSEEKIGVYTTRPDTVYGVSYVVLAPEHPLTQIVTTSEQKAAVEAFIKEVSNQSELERTAEDKPKRGIPTGGKVVNPFTGEEVPVWIADYVLYEYGTGAVMGVPAHDVRDFKFAKEQNLAIKVVIVPEVGAEETLKSAYTEAGILVNSGDFNGMNSLEAKKAIIEFAEKQNFGKLRIQYRLRDWLISRQRYWGAPIPVIHCPNCGIVPVPDADLPVQLPEDIELSGRGGSPLAQLESWVNVPCPTCGTPAKRETDTMDTFIDSSWYYLRYADAKNEEKIFDSSKVNDWMPVDQYVGGIEHAILHLLYSRFFTKVLRDRGLFNFDEPFQRLLTQGMVQGLTYMNPNKGGKDKWIPSHLVDANNPVDPQTGEPLQRLYATMSKSKGNGVAPEDVINKYGIDTARMFILFKAPPEKDLEWDEADVEGQFRFLNRVWRLVTDYAAAGVCKQKAELDKLSKVEKDLRRAIHIAIQAITEDVEDEYQFNTAISELMKLSNALTDAKCNNSPIYAEGIQTLVILLAPFAPHIGDELWQLLGNKNSVHTQTWPSFDPAALIADEITLVIQIMGKTRGSIQVPSQADKAELEKYARESEVAQRYIEGKEIKKVIVVPGKLVNFVLG
>NC_019771.1|WP_015215449.1|3906443_3906902_-|50S-ribosomal-protein-L9
MAKRVQLILNQDIYKLGKSGDLVDVAPGYARNYLIPQKKANHATPGLLKQVERRREQERLRQLELKQQALEQKATLEKVGSLKIAKPVGENEAIFGTVTTQDVAEAILAATSQEIDRRGITIPDINHLGTYKAEIKLHSEVTAQINIEVIAS
>NC_019771.1|WP_015215450.1|3907107_3907881_-|hydroxyacylglutathione-hydrolase
MQIISLAALSDNYVFLLHDSKKNIAAVVDPADSQLVLQQLAQLKAELVAIFNTHHHHDHVGGNQQLIQQFPQVVVYGGVEDRGRIPGQQVFLQDGDRIQFSDRTAEVFFVPGHTRAHIAYYFPPTTADETGELFCGDTIFSGGCGRLFEGTPTQMVDSLTKLRNLPDNTRVWCAHEYTLGNLRFALTVDGENPDLQRRFAEVTAMRQHQKPTVPSVLGIEKLTNPFLRWDQPSLQLAAKSSDPVQTFARLRAMKDQF
>NC_019771.1|WP_081593697.1|3908175_3908691_+|alpha-1,2-fucosyltransferase
MQNLDNFQPLAKYQENVASLISSIRKQTDIVIGVHIRQGDYQKHQGGRYFYTVEQYLKVMEDVIELFPNQKVTFLICSNNQQDPKYFQHLSYVYGNNHIIEDMYSLAKCDYIITPPSSYTMWASFYGEKPLYMIRNTTKSPKIKDFVHFYQWKGVFSYDEDWSKSFWEWTH
>NC_019771.1|WP_015215451.1|3908717_3909560_+|hypothetical-protein
MRSATKGFITILTGLYPFQDCVHFLASVRKFHQEPIIILIDQVPKTLYPLLTRFKNIILKPAPANENPVLASREAKLALYDASEFDKTIYLDSDTCLLSDLNDVFNHLDEYDLLLTEDVQPAISKATNLLRGNQKELLPHVLTILQSLDLPLQNDSIQYNSGLIAFTKTEKNHIFFKEFKHYFEIVKNNQDQLLLKDQGAFASAIAATKPKIKILPPTYNYMSKWQDAYQIDTPIKVLHCTYPYRPQYAKNITRSLYTRVFDKLAQVFLPNQVTNPWRKK
>NC_019771.1|WP_015215452.1|3909677_3910850_+|glycosyltransferase-family-4-protein
MKISILVSDLSSAGAGRWGGGSVRSFLLAQALQKLNHQVEILGFVFGQETAVIPKSEIMINHFTGYNYPKFLISASQLLKRLDGDIIYAMRPKPTTFGLALLQKLTTKQPIILDIDDWELSWYGGEKWQYNFSWKQIYRDIFKPDGALKNPDHPLYLQKVERMTHKADAITIHTKFLQDKFGGTYIPNGKDTELFNPNYYDPEASRSYYGLSGYKILMFPGAPRPYKGVEDVLMALEILNEPDLKLVIVGGSPYDDYDVQLSEKWGRWIIKLPKYPSTEMPKIVAAAHIIVVPQRDTPAALAQFPLKLTDGMAMAKPILATRVGDIPEILGETGYLVDSEAPAQLAEKIKLIFEDLDTANQRAVKARERCVEKYSINSMSSVLESVITNL
>NC_019771.1|WP_015215453.1|3910939_3913189_+|ABC-transporter-ATP-binding-protein
MSTRKLLLRFAKPYPVLIVSTILLGFSGALFNGISTALIVPVILKIVGQNIDFKGAPGILKILLNPFDGVPENYRIAVMAVAVIGTIALKNLFAYISSLTSSSLTRMLTSDMREAGLSILLKVDIDYYTKMKVGDLMNRLGGEMSRASSAISNVVKLTTLSITILVFIGLLLSISWQLTIAATALMLVVTLLNQYFISRSKKFGKQLSELSKAYSIAVLEILNGIRLVKSTGNETREYQRIQKLIKDREKADFDSQANSQAIGPLSEFMGITCLLIIVFLSKTLFANQITAVSTVLLTYLLVLLRLLPLISQLNGLRSNFASTATSVEMVSEFLRLEDKPFMGNGKLPYKSLEKGVHFKSISFAYTGNKQQVLKDINLYLPCGTTLALVGGSGAGKSTLADLLPRFYDPTSGCITFDDVDLREFDLASVRKHMGIVSQDTFLFNDSVRNNIAYARPEATEEEIITAAQRANAYEFINKLPQQFDTLIGDRGVMLSGGQRQRLAIARALVQNPEILILDEATSALDTVSERLVQSALDELSQNRTTLVIAHRLSTVRKADQIAVLDQGRVVEVGTHEELLKKDGYYSQLCSMQFANNSDTSGKRNQSLLRISYEIRTQLNSMIGLMRLLIDDLVDDSQERQELLEESYKSAWRIINTVDVFDDVINKQIKGQLVSIAEQNRSGITTYYQNFTYLFDEFRSSLNPIFACLRTLADHVEEPIEFQNQLLNEAYESAIYLLGNLEKFEDNIKI
>NC_019771.1|WP_015215454.1|3913193_3914405_+|glycosyltransferase-family-4-protein
MKNNILAKNYIFFINEELPKPEAHLVQSTNAANGAANLDYATVLVYPQKGLSAINPWYLARPFQPQKIPAKLVNYYNLQDKLKVAPLPMPWPIDNWQNKITNSNTIATKYYLPLHIKPTTQLVHSRNWNFIKAAIKNDIPAIYEHHHHDHKKFEPEIVKNPLFQIAITVVDTIRETMIENGMPPEKVITLHNGFNRLFMERQPEKSRLWREKLLQDERTKLVVYAGALKQFKGIDILIEVAREMPNVQFACAGGKPAEVEHYQQLAKDKQVENITFLGYILHNELSSLLQAADILAHPHCLGKAATFTSPLKLFDYLASGNPVVATEIPSLTEFKNTPAIAAWCEPDNPTKFAAALQQVLATHPKKIAGYPEIIDFVKQFSWENRAAKILSHIDQSFLPQLIP
>NC_019771.1|WP_015215455.1|3914429_3915383_+|glycosyl-transferase
MKTVGMISSYRALESRADWLWQQTPHPFGVWENIKMQALAEKPDFLLMYQFDFPRPSPPPSLLDRLRKKQPKPELNIHNLLRNVSKEQIIYLLREPPLDEILEINKRNYQQAENYCGYISGPDDFAPIPNYMPAIWYHSNSFKDLNEMPCPQKVSNCSWITSGINRTANHRQRLDFLQSLKSSGMQIDFYGRGLEKWVKTSGELGNKWYGMAPYYYNLAIENYADNSWYVSEKLWDSLLAWCLPIYYGGQAADKLLPPGSFLRLPSLDEKGIAYIQEITATPDAWYAAKDAIAEARQIILHKLNLLNWLSEFATKFS
>NC_019771.1|WP_015215456.1|3915419_3916418_+|hypothetical-protein
MDGICTLANDRVYDQLIALINSIEAIYGQTMPVCIYPYDHNTEKIAAELVHRPHVTLYDHQDSIQKWDKFVKDIWDTHPTAQTHWQKLGSYQYHRLGTHRRYCAFDAPFDRFVYMDADTILMSSLDHIFTQLSHHDWVVYDFQFKDLSHVYSLSSTKLKELFTPERLQTEIFCSGFYGSKKDIFPEPNREMILDFLRQGEAEVLYDMAPDQTILNYMVMRLGLSNYNFALELPADQTTGCSVTSLHFENRDQILYDKGNRLTYLHYIGLSSKLFHRVCTGENIDFPYRDIFLYYRYLHEPEQRPKFTTKAKAYNAVPSLGTRILNKLKLAKK
>NC_019771.1|WP_015215457.1|3916429_3917359_+|hypothetical-protein
MNRGIYIIANDKVTDQAIALLNSIRLHDADTPVVMIPYDDNYHAIADILGKNYGVKIYEDLDFIARLSQRLYETFGGQFFARPNQFRKQACWFGEFDEFLYIDTDIVVFEKIIDNLNYLQNTDFICCDYQHLGGIKNVFNSQVLEDKVFSKDEVKEIFNGGFWGSKKNLISENDLYETFAECASHPEYFDFSEKTSDQPIINYMLLKRIPRRFNIVRREGKAPGNWGGTPHFQTQGNILFDPTVNQPLQYLHWAGIKIQPGCPYWETWEYYRNLNSSIPAAAIPAPVKKSQWQQTVDNIKNQVKQLRSK

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Crispr_ID: NC_019771_16

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_16

4076915-4077042

Orphan

A:N

Consensus_repeat	Method
GATTGAGGAATTAAACAGAATGCTGAGTGCATTATCCTGAAAATCCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019771_16

>merge|NC_019771|16|4076915-4077042|CRISPRCasFinder
GATTGAGGAATTAAACAGAATGCTGAGTGCATTATCCTGAAAATCCTTAAATCCTGAGCATCCTGATTCAGACAAAATGAAGATTGAGGAATTAAACAGAATGCTGATTGCATTATCCTGAAAATCCT

>NC_019771|16|16|4076915-4077042|CRISPRCasFinder
GATTGAGGAATTAAACAGAATGCTGAGTGCATTATCCTGAAAATCCT	TAAATCCTGAGCATCCTGATTCAGACAAAATGAA
GATTGAGGAATTAAACAGAATGCTGATTGCATTATCCTGAAAATCCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015215594.1\|4078577_4079165_-\|Uma2-family-endonuclease	unknown	unknown	gnl\|CDD\|368559
NC_019771.1\|WP_015215596.1\|4079667_4080108_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|224321
NC_019771.1\|WP_015215599.1\|4082993_4083242_+\|DUF5340-domain-containing-protein	unknown	unknown	gnl\|CDD\|375096
NC_019771.1\|WP_015215584.1\|4063631_4063928_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370734
NC_019771.1\|WP_015215585.1\|4063933_4064257_-\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|183845
NC_019771.1\|WP_015215586.1\|4064456_4065011_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015215593.1\|4077058_4078351_-\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NC_019771.1\|WP_150111027.1\|4072012_4075552_+\|FkbM-family-methyltransferase	unknown	unknown	gnl\|CDD\|226428
NC_019771.1\|WP_015215598.1\|4081922_4082807_+\|indole-3-glycerol-phosphate-synthase-TrpC	unknown	unknown	gnl\|CDD\|215254
NC_019771.1\|WP_015215588.1\|4069393_4069846_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015215592.1\|4075829_4076768_-\|serine-hydrolase	unknown	unknown	gnl\|CDD\|379138
NC_019771.1\|WP_015215590.1\|4070819_4072007_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NC_019771.1\|WP_015215589.1\|4070083_4070536_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_042465138.1\|4085064_4085292_-\|DUF2949-domain-containing-protein	unknown	unknown	gnl\|CDD\|371402
NC_019771.1\|WP_081593699.1\|4075597_4075732_+\|DUF4351-domain-containing-protein	unknown	unknown	gnl\|CDD\|316753
NC_019771.1\|WP_150111026.1\|4065265_4068520_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015215595.1\|4079281_4079671_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015215600.1\|4083474_4084626_+\|alanine--glyoxylate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223153
NC_019771.1\|WP_015215597.1\|4080392_4081823_+\|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl\|CDD\|235798
NC_019771.1\|WP_015215602.1\|4085808_4086336_-\|DUF192-domain-containing-protein	unknown	unknown	gnl\|CDD\|376876

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015215594.1\|4078577_4079165_-\|Uma2-family-endonuclease	gnl\|CDD\|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	1.23466e-17
NC_019771.1\|WP_015215598.1\|4081922_4082807_+\|indole-3-glycerol-phosphate-synthase-TrpC	gnl\|CDD\|215254	PLN02460, PLN02460, indole-3-glycerol-phosphate synthase.	6.53589e-141
NC_019771.1\|WP_015215599.1\|4082993_4083242_+\|DUF5340-domain-containing-protein	gnl\|CDD\|375096	pfam17275, DUF5340, Family of unknown function (DUF5340). This family of unknown function can be found in Cyanobacteria.	5.70367e-37
NC_019771.1\|WP_015215584.1\|4063631_4063928_-\|hypothetical-protein	gnl\|CDD\|370734	pfam09876, DUF2103, Predicted metal-binding protein (DUF2103). This domain, found in various putative metal binding prokaryotic proteins, has no known function.	5.92948e-27
NC_019771.1\|WP_015215585.1\|4063933_4064257_-\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|183845	PRK13019, clpS, ATP-dependent Clp protease adapter ClpS.	1.57887e-58
NC_019771.1\|WP_015215590.1\|4070819_4072007_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.77678e-18
NC_019771.1\|WP_015215596.1\|4079667_4080108_+\|HNH-endonuclease	gnl\|CDD\|224321	COG1403, McrA, Restriction endonuclease [Defense mechanisms].	5.5756e-10
NC_019771.1\|WP_150111027.1\|4072012_4075552_+\|FkbM-family-methyltransferase	gnl\|CDD\|226428	COG3914, Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones].	6.20286e-100
NC_019771.1\|WP_015215592.1\|4075829_4076768_-\|serine-hydrolase	gnl\|CDD\|379138	pfam13354, Beta-lactamase2, Beta-lactamase enzyme family. This family is closely related to Beta-lactamase, pfam00144, the serine beta-lactamase-like superfamily, which contains the distantly related pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	2.80243e-16
NC_019771.1\|WP_042465138.1\|4085064_4085292_-\|DUF2949-domain-containing-protein	gnl\|CDD\|371402	pfam11165, DUF2949, Protein of unknown function (DUF2949). This family of proteins with unknown function appear to be restricted to Cyanobacteria.	6.92701e-30
NC_019771.1\|WP_015215593.1\|4077058_4078351_-\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	6.95081e-96
NC_019771.1\|WP_015215600.1\|4083474_4084626_+\|alanine--glyoxylate-aminotransferase-family-protein	gnl\|CDD\|223153	COG0075, COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism].	3.45495e-156
NC_019771.1\|WP_081593699.1\|4075597_4075732_+\|DUF4351-domain-containing-protein	gnl\|CDD\|316753	pfam14261, DUF4351, Domain of unknown function (DUF4351). This domain is found in bacteria, and is approximately 60 amino acids in length.	1.18311e-13
NC_019771.1\|WP_015215597.1\|4080392_4081823_+\|dihydrolipoyl-dehydrogenase	gnl\|CDD\|235798	PRK06416, PRK06416, dihydrolipoamide dehydrogenase; Reviewed.	0
NC_019771.1\|WP_015215602.1\|4085808_4086336_-\|DUF192-domain-containing-protein	gnl\|CDD\|376876	pfam02643, DUF192, Uncharacterized ACR, COG1430. Two structures have been solved for members of this large (>500 members) family of bacterial proteins present mostly in environmental bacteria and metagenomes (distant homologs are also present in several Plasmodium species). TOPSAN analysis for Structure 3pjy shows that there is much similarity with the other solved structure, Structure 3m7a, solved for UniProt:Q2GA55 (Saro_0823), a homolog of Thermotoga maritima TM1668, UniProt:Q9X1Z6., The homolog in Caulobacter crescentus (CC1388), UniProt:Q9A8G6, is associated with CspD, a cold shock protein (CC1387), UniProt:Q9A8G7. However, the genomic context of UniProt:Q2GA55 is most conserved with a putative xylose isomerase, suggesting a possible role in extracellular sugar processing. Saro_0821, UniProt:Q2GA57, is annotated as an AMP-dependent synthetase and ligase. Structure 3m7a structure corresponds to the C-terminal (27-165) fragment of the YP_496102 (Saro_0823) protein and it is structurally unique, as the best hits from Dali have a Z-score of 3.8 (1nt0, 2j1t, 3kq4) and it is thus a likely candidate for a new fold. Interestingly, many of the top Dali hits are involved in sugar metabolism. There are no obvious active site-like cavities on the protein surface of 3m7a (http://www.topsan.org/Proteins/JCSG/).	2.64107e-45

>NC_019771.1|WP_015215592.1|4075829_4076768_-|serine-hydrolase
MVFFNKDEQLENLGNEILEATWSNFASLARNQIALTWVVYDPPVLVNTGGALTPDAFWSHPVRGFSYRGVERIYPASVVKLFYLVAVHEWLGKGMTQTSKELERALRDMIVDSSNDATSLIVDILSGTTSGAELPAGPFETWKYQRNIINRYYQSLGWEEMGTINVCQKTWGDGPYGRERAFYGEMFENRNMLTANAVARLLHSIVGGVAVSSVRSQSMMSLLKRSIKADELPQDVEEDQVTGFIGGGLPENSQIWSKAGWTSSVRHDAAYIELPDQHPYLLVVFTEGKAQAKSREILPFVSRKIAEAVSNL
>NC_019771.1|WP_081593699.1|4075597_4075732_+|DUF4351-domain-containing-protein
MVELLTKRFGELSVEIRASISALPLPVMEDLSEALLDFTSLADL
>NC_019771.1|WP_150111027.1|4072012_4075552_+|FkbM-family-methyltransferase
MPQLTEQINDTGAILVRERKWEQAKNCFKSVIELDPDCVLGHYNLGCVLQNQKYYPEAIFSYHRALKINANHIDALKNLGYVYYKNGQGDLAEKCFQKILQLNPNHAETYEILGFIAGEQGKLSECISLLNEALKINPNNPKLHSCFLFNLSSLISFTPQQILDSTQLWYEQQVVNQWLPTLTTNRNDKTPHRRLRIGYISPDFRRHSVSTFIKPIFQHHDRTQVEVFCYGEVNEPDAITDEIIDICDAWRSTVGLSDLQVAELIQTDHIDILVDLAGHTANNRMIVLGIKPAPIQTTYLGYFATTGLPTIDYWITDEVLHPHDTQEKTSETIWRLPRCYVGYEPLKNAPEVTELPCKKTGIFTFSSFNNLRKLTPETFALWIEILKAVPNSRLVLKCASSDVFSPLIAEKIQTPFVEQGIDPKRIFLYGGYAADEDHLNLYNQVDLHLDSLPYTGCTTTCEALWMGVPTITVAGTRKMERMSASILHSVGLDDCIAYSAVEYVEKAIALARNPDYLQSLRSTMRERVQHSPLLDVKNMTSTLEAAYRQMWQIYIEQESKIATSENPPTNASFPVDLEFADAVNYYQQYLENNPNDAQAYYYLGQAYQGLDDVENAIPSYLQSLAINRSSAATYQALGQLLAEQELIDQAEKYYRCAVLVEPNNSEIQQNLKLFLQQYCSKTAKKIIPIFLKNANNSEELKYFKFIDADHLQPDECLVEIEGGIKICIKNDLNSLTSYVLLEQGDWFEPEMEFVRKLITPGMEILDIGANHGVYTLTMARLLQGQGKITAYEPASSVVSLLRKGVEANGFTNVEIINAGLSDCEGEATLFLSTNSELNSLQQDGLSQQQETIKLLNLDRELEQHNWQKIDFIKLDAEGEEAKILAGGKRFFFEQSPLIMFELKHGKHINMRLIQLFQNLGYETYYLVSSIGCLVPFDVNQPVDGYQLNLFACKIERSQQLAERGLLVTEIPEKPLLTNPSYWLEAIAILNYATPFLNQWQEYATVSKTDSQVYLEGLNYFFLAKTPSLSQSEQFAALKYSFECIQQAVQAKPSLTRYCSLARVAAELGKRQVSVETLQQLITYLNSGSLIKVDEPFLPVSQQYDHQIFNNNLQDWLLVSIIETFENRRVFSSYFSVQQTVSLLNQIVQKPFHSHQSESRLILANKRIEGELYAIGSIKI
>NC_019771.1|WP_015215590.1|4070819_4072007_+|tetratricopeptide-repeat-protein
MIIFCGGTAQNLRTLSYNLCQALLTQTGRTNIQGTTCKTATEIDAYFKIIEKPALPILIQYQVLSELALEVIHHGQAKSVYLHQDPREILTTVITSPKQKETFESTFINLWQQYQEQWFSDVNQTLLIRKENLLAQPHSEIGRLSTYLEIESTKPEIELLLKQYRLEQEKSEEWQQILNPQQCLIIETLLSPLLLQFHDEDESSLFQKIEQNLVSIQLEPLLIQIDKLLGQIGHFKSEKLREQFYESIDKCLITALTARGRLQEAAEVYHLLGKFLTLQNDLQFSEKWYLRALSIQPQLAKSYYNLGFVYEQQDKWEQAIDNYTHAITINSKYTKAYYRLGLIFKRQKHFIKAIEQFSQVLQLDADHQGAKFNLALLWQQGEGADFIQNLLEKKS
>NC_019771.1|WP_015215589.1|4070083_4070536_+|hypothetical-protein
MNTNCTHISKASVIAFLLVGIAVAASFIQEKPAQAQFIGTDSQSRVSAAVTSILSNGTTNSFASEIVFPQDSISPSGHLTLKIIYGAVGHDPSQVTIIKGNMNAGTVNYTDNSIQSAIARAINSAINDYRFGDIIGIVKSWQSGGSAALD
>NC_019771.1|WP_015215588.1|4069393_4069846_+|hypothetical-protein
MNAKSNKTLKAAAISSLLAGGAVAASFISAEPAKAQFIGADSQSRVSGAITSVLSNDVTNSFAAEMVFPEQSIASSGTVTISATYATVSADVSQVAITTANMSAGTATYSASTVEAATARAIDSAEAATRFGDIIGIVKSWQSGGSAALD
>NC_019771.1|WP_150111026.1|4065265_4068520_-|hypothetical-protein
MTLLPIKTIANEKEPVNDLPSVNATNENSHTEKQLELEEVALEQKDLTPSFPEKTDVISFSAEQKLIKAKINSIHNSAYKLPEKRLHTTIGCRGHTLENYPFTPIIRADKPHTQEEFQPEISSCEENNTSFTLSDYSASEIIYGDYEQNINTKSIITPYYSKSLPEVTLKKEKLIAQSTNNQIQSQFNPVEPNLPVLPKEVPSLPIPEEKPEKNPEEKPEKPPQLTPEENRKVLRTLMRNLLNNSASRYPFFVNTSDKLIINPRNFQPLNFEFYSDFTFDLDKFKTGNPFQKDEFSDILIKSANISFYPEDEQFYWVLDGNRVVIETEGRHLNVGYQGNSNQQKIRQIAKVSTVFWGVQTVFAIPNIFEDLVGNKKLDDLNIISGAAEIVLPPGANLADNASFTINVTRPDGSFFEKFIPLDDTRKATTNALLGGGSFFGNLDATNTPRFLQGFPTVNLQPLLNNGVKLEIGSIIPRENLAAAGLILGDVFTKQGFSFNSPITSFPGIKTLQVNQSDNDDIVAVLSNPFLTKEQKDFHYLNSLMWYNLGQQSPEVATFSISDPQNKDWFRYTLSWSHNRTLLKYDPEKINLNYLNVFSNPGLSITTAQWEDTDLNQTMNASFGLMLGSVFNFINPGNLNQSISEAKEKYKNLQPLATLNTKATSQQRRQMNQRLNDTLNYGNTNSNFSQVSGSYTFASNITPDSSLLFQLRTGIYRRSVQFIEQKIEPWTPEAPVIIDFVRPSDLGPIFFTGINIPTNLTQINAPETFEVTFIRGETSDGEVLFDQSYVFDNNLSSMFTAVPIIGPGKSYDLDFGRIKLSTFPQRDIETSAYTGHLYLPAIELVASGSIDNFSYALSTGMWFNLFPDSAPVIDSNLGNLNSNATVETSIGGMLKFAAKADFQNIFYDDKKQWHTIIANSPFFSLTYNTNPNRLNLSNISLGNVFQFAKPDFNITFYPVLSYSPKFLNPDVKSNSLGDMSAFLLLNFSHKIGFDFNSSISLGNQALYQFETTYNIIKSKNFGTLKIGPYYTNNSMATKGFEGQLVDPNYGMIFRYESASSGLVIDSRLGNSEYGFRGQLNMELKF
>NC_019771.1|WP_015215586.1|4064456_4065011_+|hypothetical-protein
MTPKIQPTAHPQVKGLILTLLLSVLMAETAQAQSIPSINIPTIKVLDISVIRPSINIPKPTIKIEIPSVIKPQDNIFKQPTNFVINGAANNTRPSFISVIQDGINIPQIQTGIGQTTVIENTKINTTINIPTATTTLSTINVVVPSTNIVDPGNINFNVTTTPISDQGSVMNSVNLSLPLPILD
>NC_019771.1|WP_015215585.1|4063933_4064257_-|ATP-dependent-Clp-protease-adapter-ClpS
MVTRLAAIYGMATAPTVTPDRVNQVTRKTYPNYKVIVLNDDFNTFQHVAECLLKYIPGMSSDRAWDLTNQIHHEGQAIVWVGPQEPAELYHQQLRRAGLTMAPLEAA
>NC_019771.1|WP_015215584.1|4063631_4063928_-|hypothetical-protein
MNKPTDGRLVWNHSTHISGLIPILERLCRHDGIHTVTPAVIGRVRGHCPKMQLRVSVPIRGGYKVIARQGKTVQEVFILTTLLQEQLESAIAIAMRIT
>NC_019771.1|WP_015215593.1|4077058_4078351_-|ISL3-family-transposase
MKFSVDQILNLPDMKVLDFQELVGAEIIITIEKAVKDSTCPDCGKTTHSIHQNHWRMIHDLSWSEKLVLLKINRRQFKCNKCKKVFSCKVAPLGETPRPHFALSEKLSFVDKSKGYTKRLAIDIVAQVLDSNIHSVAERNDLSDEEVESMLKAQVSQILNINLSQVKRLGIDEIALVKGQGNYLAVLVDLDTRKPIELVKSRRIEEIREVVVKWGSQVLEQIVEVSIDLWSPYKSLVEELMPNANITADRFHVMKQVNDELDAMRKSEKKAAMSLDNKSEQDRILAGLNKSKYSLIKNEDSLNEQQKERLNNVQEVSPILAKMHALKEEFRDIFESTKSWGESIMNLLDWMHDGLSYFPKSIGTMIRWFGEVVGYFDGRTTSGTVVRVAFRRKGINNKLKLIKRLGYGFRNFSNFRLRSLLNWHFSINSP
>NC_019771.1|WP_015215594.1|4078577_4079165_-|Uma2-family-endonuclease
MKIPLLEQKEGKLVTVPGVSWQQFKTIEVQLQENHAVKLAYLAGVLEIMSPIGDKHEYVKKTLSYLLEAYMRHKGIRFYGRGGFTLEESGYASGTPDESYCIGTNKEVPDIVIEIIVSSGTIKRTELYKPKRVPEIWFWKNNKIQIFSLNAVFEYEEVNRSRFLTDLDKELLLQFLAIPDQYDAVSQFIEFISEK
>NC_019771.1|WP_015215595.1|4079281_4079671_+|hypothetical-protein
MSNQITITLPDDIYQKAEHFARLANRDLASVLVDTIQFSIPPVSLEAAILEPVSTLSDEQVLALTELQMEPEEDSCLSELLDKQQAGMLTESEHSELQALMQIYQEGLLRKATALSEAVKRGLIKELGA
>NC_019771.1|WP_015215596.1|4079667_4080108_+|HNH-endonuclease
MSSSQISEEVRVRVRTQANHQCGYCRSLQKYVLGILEIEHIIPKAKGGTDDEENLWLACRLCNSYKGTQTHGLDQITDRKIKLFNPRQQKWSRHFAWTNNGTHIMGLTACGRVTVLALQLNNIYAVTVRQAWVTAGWHPPKDNVKE
>NC_019771.1|WP_015215597.1|4080392_4081823_+|dihydrolipoyl-dehydrogenase
MSSEFDYDLVIIGAGVGGHGAALHAVNYGLKTAIIEAADMGGTCVNRGCIPSKALLAASGRVRELRNAHHLKSLGIQIGSVEFDRQAIANHADNLVSKIQGDLTNSLKRLGVDIIRGWGKIAGAQKVTVTTDSGEKTITAQDIILCPGSVPFVPPGIEVDGKTVFTSDQGVKLESLPKWIAIIGSGYIGLEFSDIYTALGCEVTMIEALDVLMPGFDRDIAKLAERVLIAPRDIETKVGIYAKKIIPGSPVVIELANFQTKEDLEVLEVDACLVATGRIPATKNLGLDAVGVELDQRNFIPVNDSMAVLSAGEVVPHLWAIGDANGKMMLAHAASAQGIIAVENILGRDKKVDYRSIPAAAFTHPEVSYVGLTETAAQELGLAEGFEIATSKSYFKGNSKALAENEADGIAKVIYRKDTGEVLGVHIFGLHASDLIHEASAAVANRQTVQKLAYLVHAHPTLSEVLDEAYKRAIAS
>NC_019771.1|WP_015215598.1|4081922_4082807_+|indole-3-glycerol-phosphate-synthase-TrpC
MQIRRRSPSQAIDISILRYQIAMPNSTPNNILEEIVWQKEIEVEQMRERQPLAELQKKLVTAPSTRDFIAALRQGKTKPALIAEVKKASPSKGVLRADFDPVEIAKSYQAGGASCLSILTDTKFFQGSFENLSLVRAAVDLPLLCKEFIIYPYQMYLARINGADAVLLIAAILSDQDLQYFVKIANKLKMAALIEVHSLGELDRVLALEGVSLVGINNRNLEDFSVDLQTTCQLLKERGSQLQEKNILVVSESGLHHPEDLSVVETAGASAVLIGESLVKQPDPKLAITNLFGK
>NC_019771.1|WP_015215599.1|4082993_4083242_+|DUF5340-domain-containing-protein
MEQLPLPAPIHYELILQLLEKQTMNAVSQNSDLQHQVSQLIVTLRKAASQQKRLEENCQASAVTVDHRWSLNHHGGKVITPD
>NC_019771.1|WP_015215600.1|4083474_4084626_+|alanine--glyoxylate-aminotransferase-family-protein
MDDKLMLMIPGPTPVPEAALLALAKHPIGHRTSEFSNMMGEVTQNLKWLHQTESDVLMLNVSGTGAVEAGMINFLSPGDRILVGSNGKFGERWVEVGQAFGLNVEAITAEWGQPLDPDKFAQKLQADTNKEIKAVIITHSETSTGVINDLVAINSHVKEHGQALIIVDAVTSLGAYNVPVDALGLDVVASGSQKGYMIPPGLGFVSVSPKAWEAYKTAKLPKYYLDLGKYRKATAKNTTPFTPPVNLMVALHTTLGMMKKEGLESIFTRHERQKNATRAAMKALNLPLFAADECASPAITAVATPGMEADKIRSLMKKRFDIALAGGQDHLSNKIFRVGHLGFVSDRDILSCIASLEVVLLELGHENFNSGAGVAAAARVFSN
>NC_019771.1|WP_042465138.1|4085064_4085292_-|DUF2949-domain-containing-protein
MIIHSTQGGEIKMAPSRYSRLINFLQEDLAISAASLAVALRHREQDPGSLTMILWQYGLITLEQLEQIYDWLETA
>NC_019771.1|WP_015215602.1|4085808_4086336_-|DUF192-domain-containing-protein
MLRRLSLFPILLSVLLMGCSPATTAKPPTVTSGSQIQTSIPKGQNLPISAEATLPKGTKIKLEVAETPEQQMMGLMYRPALPDDRGMLFVFPSAQPVKFWMMNVPVSLDMVFLHNGVIKYIQTAAPPCNSQPCPTYGPNVPIDRVIELRAGRATELGLQVNDQVKIKFLKSGASE

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Crispr_ID: NC_019771_17

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_17

4112634-4112750

Orphan

A:N

Consensus_repeat	Method
AATCAGCATTCTGTTTAATTCCTCAATCTTTATTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019771_17

>merge|NC_019771|17|4112634-4112750|CRISPRCasFinder
AATCAGCATTCTGTTTAATTCCTCAATCTTTATTTTGTCTGAATCAAGATTTCCAGGATTTAAGGATTTTCAGGATAATGCAATCAGCATTCTGTTTAATTCCTCAATCTTCATTTT

>NC_019771|17|17|4112634-4112750|CRISPRCasFinder
AATCAGCATTCTGTTTAATTCCTCAATCTTTATTTT	GTCTGAATCAAGATTTCCAGGATTTAAGGATTTTCAGGATAATGC
AATCAGCATTCTGTTTAATTCCTCAATCTTCATTTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015215619.1\|4111860_4112556_-\|C40-family-peptidase	unknown	unknown	gnl\|CDD\|366353
NC_019771.1\|WP_015215611.1\|4098207_4099290_+\|class-I-fructose-bisphosphate-aldolase	unknown	unknown	gnl\|CDD\|236431
NC_019771.1\|WP_015215615.1\|4103241_4104249_-\|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl\|CDD\|223740
NC_019771.1\|WP_015215618.1\|4110016_4111864_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197231
NC_019771.1\|WP_015215610.1\|4096724_4097531_-\|ADP-ribosylglycohydrolase-family-protein	unknown	unknown	gnl\|CDD\|224315
NC_019771.1\|WP_015215625.1\|4121582_4122815_-\|glycoside-hydrolase-family-10-protein	unknown	unknown	gnl\|CDD\|224563
NC_019771.1\|WP_171815831.1\|4101753_4103217_+\|S-layer-homology-domain-containing-protein	unknown	unknown	gnl\|CDD\|306825
NC_019771.1\|WP_015215617.1\|4105716_4110033_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|372468
NC_019771.1\|WP_015215629.1\|4125640_4126861_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|274425
NC_019771.1\|WP_015215616.1\|4104741_4105659_+\|histone-deacetylase	unknown	unknown	gnl\|CDD\|212519
NC_019771.1\|WP_015215612.1\|4099444_4100440_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NC_019771.1\|WP_015215626.1\|4123113_4123494_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015215628.1\|4124002_4125172_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|223736
NC_019771.1\|WP_015215631.1\|4127107_4128055_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|366154
NC_019771.1\|WP_015215632.1\|4128091_4129057_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319264
NC_019771.1\|WP_015215621.1\|4113842_4114631_+\|DUF874-family-protein	unknown	unknown	gnl\|CDD\|226983
NC_019771.1\|WP_042466065.1\|4117943_4119254_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_019771.1\|WP_015215613.1\|4100617_4101505_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|178283
NC_019771.1\|WP_042466064.1\|4114679_4117847_-\|multidrug-efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|273335
NC_019771.1\|WP_015215624.1\|4119970_4121467_+\|site-2-protease-family-protein	unknown	unknown	gnl\|CDD\|100081

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015215619.1\|4111860_4112556_-\|C40-family-peptidase	gnl\|CDD\|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	3.21165e-30
NC_019771.1\|WP_015215611.1\|4098207_4099290_+\|class-I-fructose-bisphosphate-aldolase	gnl\|CDD\|236431	PRK09250, PRK09250, class I fructose-bisphosphate aldolase.	0
NC_019771.1\|WP_015215615.1\|4103241_4104249_-\|mechanosensitive-ion-channel-family-protein	gnl\|CDD\|223740	COG0668, MscS, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	4.53466e-37
NC_019771.1\|WP_015215618.1\|4110016_4111864_+\|hypothetical-protein	gnl\|CDD\|197231	cd09133, PLDc_unchar5, Putative catalytic domain of uncharacterized hypothetical proteins with one or two copies of the HKD motif. Putative catalytic domain of uncharacterized hypothetical proteins with similarity to phospholipase D (PLD, EC 3.1.4.4). PLD enzymes hydrolyze phospholipid phosphodiester bonds to yield phosphatidic acid and a free polar head group. They can also catalyze transphosphatidylation of phospholipids to acceptor alcohols. Members of this subfamily contain one or two copies of the HKD motif (H-x-K-x(4)-D, where x represents any amino acid residue) that characterizes the PLD superfamily.	3.29117e-24
NC_019771.1\|WP_015215610.1\|4096724_4097531_-\|ADP-ribosylglycohydrolase-family-protein	gnl\|CDD\|224315	COG1397, DraG, ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones].	1.26752e-65
NC_019771.1\|WP_015215625.1\|4121582_4122815_-\|glycoside-hydrolase-family-10-protein	gnl\|CDD\|224563	COG1649, COG1649, Uncharacterized protein conserved in bacteria [Function unknown].	8.97607e-153
NC_019771.1\|WP_171815831.1\|4101753_4103217_+\|S-layer-homology-domain-containing-protein	gnl\|CDD\|306825	pfam00395, SLH, S-layer homology domain.	2.99777e-12
NC_019771.1\|WP_015215617.1\|4105716_4110033_+\|AAA-family-ATPase	gnl\|CDD\|372468	pfam13087, AAA_12, AAA domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.	8.36797e-59
NC_019771.1\|WP_015215629.1\|4125640_4126861_-\|glycosyltransferase	gnl\|CDD\|274425	TIGR03087, stp1, sugar transferase, PEP-CTERM/EpsH1 system associated. Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.	2.44699e-65
NC_019771.1\|WP_015215616.1\|4104741_4105659_+\|histone-deacetylase	gnl\|CDD\|212519	cd09993, HDAC_classIV, Histone deacetylase class IV also known as histone deacetylase 11. Class IV histone deacetylases (HDAC11; EC 3.5.1.98) are predicted Zn-dependent enzymes. This class includes animal HDAC11, plant HDA2 and related bacterial deacetylases. Enzymes in this subfamily participate in regulation of a number of different processes through protein modification (deacetylation). They catalyze hydrolysis of N(6)-acetyl-lysine of histones (or other proteins) to yield a deacetylated proteins. Histone deacetylases often act as members of large multi-protein complexes such as mSin3A or SMRT/N-CoR. Human HDAC11 does not associate with them but can interact with HDAC6 in vivo. It has been suggested that HDAC11 and HDAC6 may use non-histone proteins as their substrates and play a role other than to directly modulate chromatin structure. In normal tissues, expression of HDAC11 is limited to kidney, heart, brain, skeletal muscle and testis, suggesting that its function might be tissue-specific. In mammals, HDAC11 proteins are known to be involved in progression of various tumors. HDAC11 plays an essential role in regulating OX40 ligand (OX40L) expression in Hodgkin lymphoma (HL); selective inhibition of HDAC11 expression significantly up-regulates OX40L and induces apoptosis in HL cell lines. Thus, inhibition of HDAC11 could be a therapeutic drug option for antitumor immune response in HL patients.	2.80903e-147
NC_019771.1\|WP_015215612.1\|4099444_4100440_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.13538e-56
NC_019771.1\|WP_015215628.1\|4124002_4125172_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	3.77163e-30
NC_019771.1\|WP_015215631.1\|4127107_4128055_+\|glycosyltransferase	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	9.59543e-31
NC_019771.1\|WP_015215632.1\|4128091_4129057_-\|hypothetical-protein	gnl\|CDD\|319264	cd16407, ParB_N_like, ParB N-terminal, parA-binding, -like domain of bacterial and plasmid parABS partitioning systems. This family represents the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system. parABS contributes to the efficient segregation of chromosomes and low-copy number plasmids to daughter cells during prokaryotic cell division. The process includes the parA (Walker box) ATPase, the ParB DNA-binding protein and a parS cis-acting DNA sites. Binding of ParB to centromere-like parS sites is followed by non-specific binding to DNA ("spreading", which has been implicated in gene silencing in plasmid P1) and oligomerization of additional ParB molecules near the parS sites. It has been proposed that ParB-ParB cross-linking compacts the DNA, binds to parA via the N-terminal region, and leads to parA separating the ParB-parS complexes and the recruitment of the SMC (structural maintenance of chromosomes) complexes. The ParB N-terminal domain of Bacillus subtilis and other species contains a Arginine-rich ParB Box II with residues essential for bridging of the ParB-parS complexes. The arginine-rich ParB Box II consensus (I[VIL]AGERR[FYW]RA[AS] identified in several species is partially conserved with this family and related families. Mutations within the basic columns particularly debilitate spreading from the parS sites and impair SMC recruitment. The C-terminal domain contains a HTH DNA-binding motif and is the primary homo-dimerization domain, and binds to parS DNA sites. Additional homo-dimerization contacts are found along the N-terminal domain, but dimerization of the N-terminus may only occur after concentration at ParB-parS foci.	0.00337835
NC_019771.1\|WP_015215621.1\|4113842_4114631_+\|DUF874-family-protein	gnl\|CDD\|226983	COG4636, Uma2, Endonuclease, Uma2 family (restriction endonuclease fold) [General function prediction only].	5.65815e-14
NC_019771.1\|WP_042466065.1\|4117943_4119254_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	3.20803e-47
NC_019771.1\|WP_015215613.1\|4100617_4101505_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|178283	PLN02679, PLN02679, hydrolase, alpha/beta fold family protein.	4.24905e-83
NC_019771.1\|WP_042466064.1\|4114679_4117847_-\|multidrug-efflux-RND-transporter-permease-subunit	gnl\|CDD\|273335	TIGR00915, Probable_aminoglycoside_efflux_pump, The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate].	0
NC_019771.1\|WP_015215624.1\|4119970_4121467_+\|site-2-protease-family-protein	gnl\|CDD\|100081	cd06160, S2P-M50_like_2, Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the S2P/M50 family of RIP proteases use proteolytic activity within the membrane to transfer information across membranes to integrate gene expression with physiologic stresses occurring in another cellular compartment. In eukaryotic cells they regulate such processes as sterol and lipid metabolism, and endoplasmic reticulum stress responses. In prokaryotes they regulate such processes as sporulation, cell division, stress response, and cell differentiation. This group includes bacterial, eukaryotic, and Archaeal S2P/M50s homologs with additional putative N- and C-terminal transmembrane spanning regions, relative to the core protein, and no PDZ domains.	6.88863e-50

>NC_019771.1|WP_015215619.1|4111860_4112556_-|C40-family-peptidase
MSLNLLIPHSPTKEYYCNIDLNLYDSPECNRLATQAATGRYLRVTSNHQDTAVAVCLCEDDYPGWLSVQDLQFLKPTKAVYQPQFISAAEIQQHIPAVIAFTQAAKQEDNYYLWGGTVAPNYDCSGLMQAAFKSVGVWLPRDAYQQEDFTQPIDFIELQPGDLIFFGTPQKATHVGLYLGDSCYIHSSGKEQGRNGIGIDQLSEQGDQVSQAYYKQLRGAGRVIKCYKPQN
>NC_019771.1|WP_015215618.1|4110016_4111864_+|hypothetical-protein
MFLASDAKPIDDNLKNLVDKIEAQSAGLSVLAARQLRYSLRQNTVELTIKEPRQFNVLEEFIIRAGIEFEPAPTADELASILGLDAVFVKSTISTLQSLQTLAVTSPITVTTEGRLFYEKGTVPQPPYSVQIYAVTDFLGGNISFQSESLSDVTTKLPDLATFVNIENKINNISSLTLETIQQILQDSDLAFHVPEEGKIVTAFKVIPPTQIFWKTVSLFVIFDALEDKLSIQLRKGKQILEAASNWLESLLNQGKISLQTLCEVSDQTINFERQAILKQKNEEIESRLEKIRQQVLETVQEAGTAVQLRDGEINQAFLEVLNSAKNQILFYYPLISQAVVDDKFLTLLQKLVNGGVGILIGYGIAQPEEDEERQIPPEVKAKLQSIKTLEGLPGVQIFWSENSHIKEVIVDQQIHLCGCYNQLFYRGGYLPTGESVYKVTIPELVQEAYQFFANRCQNHAQKLWVIAVQNYNSQLAVESLCIWGAMGMEEIAIKEIEANNWLELVPIWLNVVIQRLRAKILPAGLQTALVLLNKFSGEEIFIDLLVQGWRRVISNIASQNPQTAVDLFSNGVWEQFLRLQIVQPTESLDTFILSQNETQKPVKKKIAKKKLEQG
>NC_019771.1|WP_015215617.1|4105716_4110033_+|AAA-family-ATPase
MPTLPNNQKSETWGYTLLNSTIDSLIRNFEGQSTVELYPEFRERRERAHELIFECVGKKSCLFYIRRQGSGKDPGEEIWDLTIATDESEFELPKRLKELRKTLGFRAAVQKNGTGGLKILSAYLLQPSRGQGDGYALPLRLQLVPNHHHPSAIPPKVLAQIATMPVCGHHVPTEEQLQAWKAFLKVEERIAKARQFCVVFVNYKYSNNKKQIAFEINLNSATLDGSEENYLDVENFWERVKQAKNQDIKFSDTVPSERNRRSSRQLGTIEKIDQKYNIIHIRLERDLVEYIAAGNYQLPGTGYLFFDAAGDIKQIERKEKALEQLRQGRTQNPYLGNFLFDASQARSIKKTVKIKSQDLLLSAANPGQKASVEKVLAADDLVLIQGPPGTGKTTVIAEICYQVALRGGRTLITSQANLAVDNALSRLVHNPVIRAVRKGRAEKVGEEGQPFLEDQVIGRWLENTATDCENNLAQRQENIKIFTQLLASSTRFKAYLESEEEFNHKQNESKLEKENLKEICQIQEIAYQESLVNQNKIESLKIGLKNLLKNVPVNWDSAEVKDFLPCLQPYTKNIHQVESFRENVCQAIKYVDELGFVRPARGAFGLAAWLSETVATEIDELKKIFSYADDVIVTMSELTTLVQAFKKDSTYLHQLQTEYQQFLNKDKSLQPTIQLWENRKREIDYIIEAVIEWKSTAYNNLYQVVKNCQQSDLPLTDNMIDLPLGLLMFANNLKLPLVPKNYKISLPDWKLLTKAISYEIQGNFTDRRGKQHSFSYFLQENFSQIPLVLSKSDRTQWQVTYQELNDYQLLTSKQRKSLVENTQSFLTKLQRTYGAAYELDNIHSTLTQITQELLDIILANSRQCVAKVKTEAEQQLNILQKQQNQLNELPNNGITQEQIFATQSQVEKASQDANLQLARVVNMLEELNKKPNIPAKLRNLTEKYLAKQSNIWEQHQEFSKQIKICESNIVKLEPLISSLEPIAILEMIQDSLHEELIKLKKETKTAQKKLDKSQIKLNELEQQLQLQIPESLIIERNWWQITWQEIPAQFKVKNTESDLFNLEFLNLVKDKFDIWQQQLQNEENYLQRYQNFVQDWINKLRQPSERDSNDLRRIYLDNANVVGITCVQAANYNFSEEFQSFDVVIIDEVSKCTPPELLIPALKGKKLVMVGDHRQLPPMLDTSTVEEVAQKIGNTREELQFLEESLFKSQFETADNSIKQMLNTQYRMHPNIMGAINQFYDGKLECGILEPDSKRAHHLAGEIIKPEHHLIWVKMPREQEFQEERLGTSFFNIREIDVIENICHQFENVWSSKVANGEPKKEIAVITFYGSQLRKIDERLQSEIFPSLQIRTGTVDRFQGMERPVVIVSMVRNNHQGDVGFAKKPERVNVAFSRAQELLVIVGCHDLFTSKPGTVGGMYSEVANIVSRHGGFIDVSCF
>NC_019771.1|WP_015215616.1|4104741_4105659_+|histone-deacetylase
MDLPIVYHLDYIAPLPLGHRFPMSKFSQLHELLLADRVAHSEQFHIPERPQTELIELVHTPNYVQAYCQGTLESKAQRRIGLPWSPALVNRTCVALGGTILTAQLALNHGLACNTAGGTHHAFPDYGSGFCIFNDLAVASRVIQKLGLAKNILIVDLDVHQGDGTAFIFHNDNSVFTFSMHCEDNFPGTKQKSDLDIPLPLGMEDEAYLQTLANYLPDLLSQIKPDLVFYDAGVDTHINDKLGKLALTDTGIFRREMQVLNTCVSAGYPVACVIGGGYAEDMKSLVWRHSLLHRAASQTYHQFHL
>NC_019771.1|WP_015215615.1|4103241_4104249_-|mechanosensitive-ion-channel-family-protein
MIEWIIPLGFILAGLFAGLIGEKVFFKKLKMFVSNRQIPGSEIIFQSLHRMTFIWFVIAGFFWAILSSPLKPDIANVLQKILTIILLYSVTLVLARLTSGFVSLSVRRTEGVPTSLLSNLAKIAVLILGTLILLQTVGIQITPIITTLGIGGLAVGLALQDTLANLFSGFYLLISQQVRTGDYVKLDDGNQGYVTDITWRNTTIKEISNNVIIVPNSKLASAIFTNYHLPAKEITLTINVGVSYDSDLELVERVTVEVAKEVMKEIAPELLQNEPYMRFHTFNDFSIDFTLYMRVSEFFDQRIGKHLFVKKLHKRYQLEGIQIPFPVRNVYMHES
>NC_019771.1|WP_171815831.1|4101753_4103217_+|S-layer-homology-domain-containing-protein
MIALSPIHSTLAASDLSATVPSEFSNYNQQLLTQKTISEEVDTDSTTNIPGETVTTTTSVKREKSGFTLAIWQPGGTISEVIARVSIKGKHGNKYYKERFLGDYKYKIKQKAKFINGFKLGDRIVVRLYDNTNRFIGYTEFACLPGHTAINLILSANPKEYQVVRVFYGVDDNEDSIVDTNTTSYDYFTQVSNQKVTFLKSSENINITQYQAAGFAKVATTGVYPVSFTEGDFALAGKSINIVDSNLAKALTAVPGSLVQLTQLSNNSTYQLSQLLSKYRQVGVAKDIKVSFSDISKDYWAKDYIAELAAMEIIDGFPDGTFRPNAPVTRAQLAALLQKIFIKSKVRNAIAFRDIPKGYWAENAIRETYEMGFFTTLGSKNFNPTQKLTRLDILITLAKGLNYQFTGSTKNILSIYSDASSIQNEHRNLIAAITQNGVVVNYPNRKLLNGKKVATRAEVCALLYRAMVSAGEVADFASKYTIQPIRE
>NC_019771.1|WP_015215613.1|4100617_4101505_-|alpha/beta-fold-hydrolase
MTISIQQSPTLEKQLWTWRDYKIQYTVMGSGQPLVLIHGFGASIGHWRKNIPVLADAGYRVFAVDLLGFGGSDKAAIEYSMEVWVELLKDFWTAHIQEPAVFIGNSIGALLSLIVLAEYPEIASGGVLINSAGGLSHRPHELNPVLRIVMGTFNKLVANQMTGKFVFNRIRQKSQIRRTLYQVYSDRNAVTDELVDLLYTPSCDPGAQQVFASILTAPPGPTPDELLLKVKLPLLVIWGADDPWTPITGAKIYEEARENGQDIKIVPIPGAGHCPHDEIPDVVNAQIVDWLAQKA
>NC_019771.1|WP_015215612.1|4099444_4100440_-|serine/threonine-protein-kinase
MMEFDVNHDADFSKVGYQVIRELGRNPEGGRITYLANSLKSQQKVVIKEFCFAKMTANWSGVKAYEQEIELLQQLNHPRIPHYIDSFAKPGFFYLVQEYKNAPSLGLKRCFHPEEIKQIALSILEILVYLQQQCPGIIHRDIKPENILVDQQLNVYLVDFGLARVQDGKTELSTLVAGSPGFMPPEEQLGYVLTQASDLYSLGATLICLLTNTSAADIGKLIDDKYRIDFQKLVPHISLHFGLWLKKMVEPNSKRRYPNAADALEALKPIQVLASGKKLDNLVAAIHQRKNIIILGLAAMGILAILGTNLMVSQPGGAANSMKIENFPKSN
>NC_019771.1|WP_015215611.1|4098207_4099290_+|class-I-fructose-bisphosphate-aldolase
MTTTLLEANSIESLLGKEAEDLLTYKAKVSSDLLHLPGADFIDRVWLNSDRTPRVLKNLQQIYSTGRLANTGYLSILPVDQGIEHSAGASFAPNPIYFDPENIIKLAIEAGCNAVATTVGVLGNVARKYAHKIPFIAKINHNELLTYPNQFNQIMFADVWQAWNLGATAVGATIYFGSEKSSRQIQEVSHAFKNAHELGMATVLWCYLRNNNFKQDQDYHLAADLTGQANHLGVSLEADIIKQKLPECNNGYGAIAKATGNSYGKTDERVYTELTTDNPIDLTRYQVLNCYAGRVGLINSGGASGKNDFAEAVRTAVINKRAGGTGLISGRKSFQRPFAEGVKLFHAIQDVYLSPDVTIA
>NC_019771.1|WP_015215610.1|4096724_4097531_-|ADP-ribosylglycohydrolase-family-protein
MLGAIAGDIIGSIYEFNNIKTKDFPLFDDRCHFTDDTILTLAVAEVILNADEFPDKTKYIDKFQYIQQFKSYYGEYPHANYGNHFMKWADSGSTEPYNSWGNGSAMRVSPIASAFDNLDIVLEEAKHCAEVTHDHPEGIKGAQATAASIFLARTGHDKTTIKSYIQKTFGYNLEQTLDEIRPSYEYDMSCQGSVPQAIIAFLESTDFEDAIRNAISIGGDSGTIACITGSIAEPFYSGVPEDIAEWIFTKLDDHLWTITDKFMSQYYA
>NC_019771.1|WP_015215621.1|4113842_4114631_+|DUF874-family-protein
MYQTDPPLSPKETLPTMYDLPSEDPEEPGLPDEFHLLQPQLLAETFRPPNYPTQEIFTGSDLNLYYDLRHPSWYKRPDWFGVLGVPYLYENRDLRLSYVVWQEGVNPHIIVELLSPGTEKEDLGQALRNVEKPPGKWEVYEQNLRIPYYAIFDRYKSEFRMFQLKGARYAEINLSDDRVWISEIELGLGVWQGTYKNVEMPWLRWYDQDGNWILTSTERERQKAEQERQKAEQERQKAEQERQKTERLIAQLRSLGVEPDLD
>NC_019771.1|WP_042466064.1|4114679_4117847_-|multidrug-efflux-RND-transporter-permease-subunit
MMVDFFIKRPVFTSVCAIIILLVGAISIPTLPTAQYPEISPTQIIVNSNYVGASAEIVESTVTTVLERQINGIEGMKYMTSSSSNDGSSTITVTFDASRDKDIAAVEVQNRVSLAEPQLPDSVKQTGVTVSKQSNNILLAMGLYSDNQEFDTVFLSNYADLYLADALKRIKGVSEARIFGERRYAMRLWLDPNKLASRNLTTQDVVDAINEQNLQVGAGQIGQQPAPDGQMYQIDLRAVSRLTEPKEFDDLVIKTTADGSLIKLKDVGRAELGAQNYSSFLRFKAQEGVGIGIFPTPGSNVLDVAKLVKKEMVRLSQSFPPGMKYQVAFDTTTIVEESLAEVVKTLFEAIALVTIVIFIFLQDWRTTLIPVITIPLSLIGTFAFVKAFGFSINILTMFGLTLSTGMGVDDAIIVVENTSRLIQEEGMSSRKAASTSMQDLFGAVIATSLVLMAVFVPVAFFPGSTGEIYKQFALTIAFSTVISTFLALTLTPSLSALLLRQRPVPGGILGWIFGLFNGFLEAARRGYERSLRFLAKIKGIVAIAFIGLLGVTAWLYMTVPSSFLPDEDQGYFITIIQGPEGSSLEYTSNVMSKVEAEILKLPEITGTFAIGGFSFSGNTANSGVIFSTLKSWDERTKPNQTVQALIGQLAQTFSGITEASVFPVNPPAIRGLGSFSGFQFQLQDISGTNTLNSLLETVGQFMMRGNQTPGLQAVFSTFKANTPQILIEVDRNKAKSMQVSIEDIFTTLQSYLGSRYVNDFNFLSRTYRVYIQADAQFRSNPNDINSLYVRSDNDQMIPLSNLVKLTPTTGAQTINHYNLFRSIEINGSPAPGFSSGQATKAMEQLAKEILPTNMGYEWSGIVAEEKESGGQAPIIFGLGLLFVFLVLAAQYENYVDPLIILLAVPLAIMGALASQSLRGLSNDVFCQVGLVMLIGLASKNSILIVEFANQLREHQGLSITKAAVEAAQGRLRPILMTSFATLLGIFPLVTATGAGSASRQSLGTAVFGGMFVATFLSLFIVPILYIIIGTIRQRLQPVHKYPLLEVHEDGKVASR
>NC_019771.1|WP_042466065.1|4117943_4119254_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MTSPEPQTDFEDIPQPSFEPPPPSRRWLRLLLALVLVIGGGSAIAWKLLTPNQNPAAANAQLPAVKVKLSTVQTGTVEDATEYIASLESRRSVNLQPRIQGQVAQIFVRSGDPVVAGASIMQIDARQQQAAVNSLSAAGQASQAQLENARATLKSLQAERLANVADVRLNQQDYDRYSELAAQGAVSRQTKDQYANRLATAKAQLGAIDSRIQAQQATISQAEKSLLQADANVRQQQVELQYYKITAPFNGTVGDVPIKVGDFVSTSTPLATITQNRPLEVNIPVPLERGSQLRQGLPVELITAQGQILGTTEVFFISPSISNNSQSILVKALYNNSAGQLRADQLIRARVIWDQRSGVLIPTTAVSRIAGENFVFVAQTEKSPEGASQLIAKQKRVKLGNIKGNDYQVIEGLKVDEKLIVSGIQNLRDGLPIMPE
>NC_019771.1|WP_015215624.1|4119970_4121467_+|site-2-protease-family-protein
MFTSSETPIIAAVVLVAFGILGWGFYRAKPFGKLGILAWLQSVVLMAPWLLFFGCFAAGIYINIAGVLLLLVASTGVYIFLGKQLRDAGQDAILKQRATERLAAETSEAANSPKNGNNSAVVAELKPEEMTIPEEDLHTIKGIFGIDTFFATETIPYQEGAIFKGNLRGEPEEVHNRLTKSLQGRLGDKYRLFLVENTDGKPVMIVLPSRNDPRPMQLPQKVFAVILLLATIATSLEASGLLLNFDLFSSPSRFPEALPIGLGICTILIAHEIGHWILAQRHQVRLSLPFFLPAVQIGSFGAITRFESLLPNRKALFDIALAGPAFGGIVSLLMLVTGLLLSHPGSLFQLPNQFFQGSILVGSLARVVLGAAVKAPLVNVHPLVIIGWLGLVITALNLMPAGQLDGGRIVQAIYGRKTAGRATFATLALLALVSLGNTLAMYWAIVIFFLQRDAERPSLNEVTEPDDARAALGLLALFLMISTLLPLTPSLAGRLGIG
>NC_019771.1|WP_015215625.1|4121582_4122815_-|glycoside-hydrolase-family-10-protein
MSETFLRWNGRQRIKSGLFAAMIVLSMVAVVMLSLPLNAQTAISQRTTSELRGVWLTNIDSDVLFESQSLQKSLQRLDDLNFNTVYPAVWNWGYTLYPSKVAAKVIGKSVDPTPGLQKRDMLKEIVSEGHKRGLTVIPWFEFGFMAPADSLLAKNRPQWLTSRSDGTKIVKEGTHERVWLSPFRPDVQSFIQDLIVEIVKNYDVDGIQFDDHFGLPSELGYDAYTVGLYKKEHRGKAPSKNPKDPEWVRWRANKITDFMKRVFIAIKANKKDCLVSVAPNPQRFSYEYFLADWQKWERMGLVEDLVLQIYRNDLNVFISELEYPEVKAAKSHIPVSIGILSGLKNKSVPMQQIKTQVEKVRDRNFAGVSFFFYETLWNLSQEKAPERQAGFRQIFPKPAGYPNLLTGWKP
>NC_019771.1|WP_015215626.1|4123113_4123494_+|hypothetical-protein
MNIKLDKHTPDNLASLFVLLMEEGMTPNQIMVGIVRLATDSKELEGTIVSADCIRFLLATMPIDTSAPGVTEFISSLAREGVTTLMLLDALGFACYVRGLFDAANIIRLTYQRLQADRIISQMLRD
>NC_019771.1|WP_015215628.1|4124002_4125172_-|helix-turn-helix-domain-containing-protein
MNIQKFIQRAEVLNNRLADLYQTATVLPFIPSDLLPDAFKDLYSTSKMVQLAVEELYQQNEELIETRNLLETERQHYQDLFEFAPDAYLVTNPKGIIKQANTAAAQLLNISSTFLVGKPIITFINREQHPYFYDELIQIFKSLQVRKLLLPFNPRDGDSFNASVTVKAISNKHGKLTNYYWLIHKTYEYQQEQSTTLDNHSHLIENLPVHKYSQGDTIPLYSQLIWYVRQGLVKLNTFCETGKEVLTGLATAGMVFGSSMTSLSIYQATALKDVELVSINISEINVLPNLSHILLPKIQQRLQQTESFLFIAGRGRVQDRLQHLLELLKDQLGEPVPEGTRLTFRFTHEEIASACCTTRVTITRLLSQLQQQGFISFDAKKHIIIKNSP
>NC_019771.1|WP_015215629.1|4125640_4126861_-|glycosyltransferase
MKILMLSSTFPYPPTRGGTQVRTFNLLKHLSQRHNITLVTQRESDVTDAEIADLRDCVDNLVVFERPPDEGKTAGLVEKIQRLGTFLLKGTPPSVLNRYSLEMQQWVDNFVEAGKCDVITCEHSVNEIYIRPHFQKYIKTLVNVHSSVYGTCLNQLATGTSENKFRDKINLPLLRRYEQSYCAKFSNIVVTTAEDKQQLQQFNSNAGIAVIPNGVDLVTFPNRPSDPGGNRIIFIGAMDNLANIDSVCFFSNEVLPEIQKKYPSTTFDIVGSRPVAEVLALKEKPGINVVGRVPSMAEYLHKSTICVVPMRTGFGIKNKTLEAMAAGIPIVGSDRGLEGLTVDAQTTPLRALRANQPAEYIAAISQLFEQPELRFQLSANARKLVETEFTWEIAGQYYEQICQGEA
>NC_019771.1|WP_015215631.1|4127107_4128055_+|glycosyltransferase
MTKITVCIPTFNRVQLLPYAIESVLNQSEQDFELIICDDGSSDDTPDLMSQYTDNRIKYIRHPQNIGKSNNMRSGFDAASGKYFIKFDDDDRLTPNFLSQTAAILEQDSSIDFVGTDHWIIDINNIRDEEATQENSHRWGRKNLPAGMVDNLLEVVFVRQSFQIGATLFRRKTLQELGFMMPNWQNCEDNDLFVRLAVAGKKGYYLPELLMEYRVHAEQQGINRAIPYLFDKIRYLESYKFEFEKLEKIRKSRLAESQLFLGLRLIEKGETQKGRELVLAGKSCSTAKAWTGLSLSFLPVGLRGWGFNFLRQVRG
>NC_019771.1|WP_015215632.1|4128091_4129057_-|hypothetical-protein
MDAAERHARIVDYLRIKPISHGQIYTFQIAVPAYEIVEVSLEKQNYLKNSLTQQGTNLIPLIVRRTEEYTEEEEYEVVYGADWCLVAKEIDIEKLWVWVFDLTDEQAVAVKQEMQQLLGNINSGEKIEPEEVDIGSLIEQKLKPIYAMINQLVSNPARNAAKYDSDDNLRVIESKIENLLSAFEAVTTFIKKVPSNSPTNIEKSHSTENINVIENRLDHLLSAVEKLTTLVEQLIPPPPPQKFNLLTATNDEIKSALKEAKVNNDNHIKGVLDAIKYWQQSGRTLTWENLQKSTKSGQHKIKNFANGTYQKLKDVADIRTE

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Crispr_ID: NC_019771_18

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_18

4752371-4758593

TypeIII

A:N

Consensus_repeat	Method
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CRISPRCasFinder
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CRT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	PILER-CR
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	PILER-CR
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	PILER-CR

83 spacers

cas6,WYL,csx3,cas10,csm3gr7,csx10gr5,csm2gr11,csm6

The CRISPR arrays of NC_019771_18

>merge|NC_019771|18|4752371-4758593|CRISPRCasFinder,CRT,PILER-CR,PILER-CR,PILER-CR
GTTTTAGTCCCCTTGCGGGGATTAGTTATGTGGAAACTGACGCTGGAGATAAGGCAGTTTACAAAGCTCAAACAGGAGGGTTTCAATCCCCTTGCGGGGATTATTTATTTGGAAACTAAAAGCCTATAAGCGTGTATCAATACACTGCAATAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACATAGAATATGCCAAACCCTTGGGGAATCCCTGAAATAGTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTGGTTGTCTCCAGCCGGACACCTCCCACCTATACAATGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCTGCTATTTATTTCTGAATCGGCTGAGGTTGAAGATGCGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACACCTGACGCTTTCCTAAGTAATCCACCTCAATCCCTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCGAAAATCTTGTCAATCCACTCAAAAGGAATCCAATGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTGTCGCCACTTGTCCTGAACCCATGCAGCAGAAAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCTATCATGCAAAATAATTTTAGATTTCTTGCTTGTAGCTTTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCTCAAAATAATCTCCATATTCTTGTTTGAAGTCTTCAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTTGACTTGCTTCTCGGATTGGTTAGCAATTTGACTTTTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACATCCCTGGAACTGATTCTTCCTGATATTGCCATCCGGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTGAGTGGATAGTTTCTATAAAAACAATCGGGGAAAGAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTTGGACGACGGATTTTAACCTCGTCGTTAACTTCAAATGGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCGTGGGGATAATCGGTTGGTTGTCGGGAATTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTTTATATTCTGACCGTGCTTTTCGGTTCTTACGTAGTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCAGGGATGCAATATTGCATCCCTCGCACAACCTCACAAAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTCCGCAATATAAGGGTATCTCTCTAAAAAATGAAGGTGGACGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCAGGCTATCGGCGGGTGTGGCCTTTTCATCCTGAGTGGTTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACGACATTTGGGCTATCTGCGGCTGACTTAGGAATAGAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTATCATGTCACCACCTCGCCAGCAGTAATCCTATGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCTATCATGCAAAATAATTTTAGATTTCTTGCTTGTAGCTTTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCAGGATTTAATTTTGTGCCATCGCTCAATTCCTTGGGAACAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTAATAAGCAAGCGTGCTATCCTCGCTTACTAGCATCTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTTTAAAGCCAATATAGACAGCAGTGTTGATATGTTTTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTAGTTGTAGAGCGTAGTCAAATAGCTCCTCAATCGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCATTCTAGAAAGAAAGATTCCATAAGAGAAGAAAAACGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCTTTCTCAATTCCGGATGCTGATTGGTTTGGGAAAGTTTTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTAAACCTGTGACAATCGGGCTGGCAGGCTTTTGTGTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCTCAAAATAATCTCCATATTCTTGTTTGAAGTCTTCAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTTTACAGGTGCGGTAGGTTCAGCAGGTGTTTGAGATGCGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTGGAAACATGGCGCACGGCGAAATCGTGATTATTGATGGAGAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCCTAAATCAACTTTAATTCGGGTAATATTGTTCTCGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTTTTGGTTGTTCTTTCATTGTTGCGACGATACAGGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACAACCTTAGAAGCGTCTGCCTTGATGCGAATAGCCCAAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACAAGTTAAGGCATGGTGCGATCGCATCTATAATCTAGGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACATTTTGACCATGAAGCGGACACATATTTGAATAGTTAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACAATCCCCTGCGCTGGCACACCTTTATTGTGTCCCGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACACTGTTGCTGCAACTGGCACGGGCTTCGGTGTTAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCCTAGACTATATGTAAACAAAGCTTACTATCCATTAGGAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTTTCCCGCTCTTAAAGGACTTGCTGAGGAAGCCAAGAAATTATGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCCCCATCAGGGATAGAGACTCCAAACCAATCGTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTCAGAGGTTAATATGTCGATGTCGAACATTAATAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTACCTATACAAAGTACCATCAATCTGGTATAGATCTTGGGGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACGCACAATTGCTTGGTCTTCCTAATAACATCATTGTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACAATTGGGAATACGGCTTATATAGAAATATGGAAAATAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACGCGACTTCTCTTAATCGCTTGCCTTGGCCACTGACAGGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACGGTAATTATCCAAATCCTACAATTTTGAATAATGAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACATGCCCTTCACCGAAGTAGCACTAGCTATGTAATATTGACGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCCAAGAATTATTTCAAGAACAATTATGCGATCGCTGGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACAATACTAGGTTATAGATGTCTGCATATTTTCTAACGCAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTAGAGAAGCAGGTAATTGAACACATAAGGAAGATAGGGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACATATATAGTGTCATCGTGCTATTATTAAAAATAATGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACGAACGATTTGAGTCTTGGCGAGTACATCCAGAAGAAAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACATTGTCGATGGCATTGTCGTTCGTGATGGGTTCCGATCCGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACGATGAATTAATCTATAATATAAGAAGTTAAGAAAATAGAGGGCAAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTCGGCTTTACCAACTTCTTCACTTCTTCCTGATCGTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCGTGGGGGCTTCCTCTGTTTTAGCTGTTTCAACTTCACGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTAGTAATTAAAACATGAGTGTCCCCCCAAAAGTTAATGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACATTTTTTGTTTTCAAAAATACTTTAAACAAGGTATTGAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCTGTGCGTCAGTTTGCATTGGATTTAGGGGTAGGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACAAGGAATCCAAGCAAGCCGCCCACCTTCATCTCCAAATTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACAAATTCAGGTGTCCTAATAATCATATACATAGCGTTTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTTTCATCTCTGCATCTCCTTTGCTTTGGTTGTTTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCTGCTAATAATGACTTCACAGGCGTGATCGCTGGTAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCTAGAAATACCCCATTTGGTTTGTTGAAATCTCTGATTTAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTTTCCCAATGTTTGCAAAAGTTTGAGTTAATGCCCGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTGGATGAGTTTTAAAATTCTCGGATGTCCGTTTTCAAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACGGGTGATGTAGATCCGACTGAGGATAATTTCTTAAAACTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACATAAAATAGCGGTGATGTTTTAGATAGTCTCTTTAGGGGGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTTTGGGTAAATCCTTAGTAATGATTGCTGGGATTATGGAGGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCCTAAAGGTACAGTTACCGTCGAAACTGTAAAAGAAATGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCAGGTGCATGAAGATTTACCCGTTGATTTCCACCTTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCAGGGGTTGTAACCAGTTATCAGAAGCCCAGTCAGATAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACGGAAAACCACAAACAGATTGCAGCAGCGATCGCCAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTTAAGAGAAAAAGAAGCAAAGAGCTTTATTGCTCAGTTGAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTTTATTAAAAACAGTTGGAAAACCGCTGATATAACAGGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACATCTCAGGGGCATTTTGACAACAAACTTTCTACTTTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCGGGATTGCTTACCCAAGCCGATATAGATTTATTTTCTATAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACAACTTTACAAAATCAATCTATTAGCAGCTTAGTAGATGCTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCAGGAAGAAAGGAGAATCAATCCAAGATTCAGGAAGGGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACACGGCAAGTTAAATTTCATCCCCAAGAAATTAGTAGGGTTGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTTAGCTAACATCCTTTCTCAAAGTGTAGAATCCGGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC

>NC_019771|18|18|4752371-4758593|CRISPRCasFinder
GTTTTAGTCCCCTTGCGGGGATTAGTTATGTGGAAAC	TGACGCTGGAGATAAGGCAGTTTACAAAGCTCAAACAGGAGG
GTTTCAATCCCCTTGCGGGGATTATTTATTTGGAAAC	TAAAAGCCTATAAGCGTGTATCAATACACTGCAATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATAGAATATGCCAAACCCTTGGGGAATCCCTGAAATAGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGGTTGTCTCCAGCCGGACACCTCCCACCTATACAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTGCTATTTATTTCTGAATCGGCTGAGGTTGAAGATGC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ACCTGACGCTTTCCTAAGTAATCCACCTCAATCCCT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGAAAATCTTGTCAATCCACTCAAAAGGAATCCAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGTCGCCACTTGTCCTGAACCCATGCAGCAGAAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTATCATGCAAAATAATTTTAGATTTCTTGCTTGTAGCTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTCAAAATAATCTCCATATTCTTGTTTGAAGTCTTCAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTGACTTGCTTCTCGGATTGGTTAGCAATTTGACTTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATCCCTGGAACTGATTCTTCCTGATATTGCCATCCG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGAGTGGATAGTTTCTATAAAAACAATCGGGGAAAGAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTGGACGACGGATTTTAACCTCGTCGTTAACTTCAAATG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGTGGGGATAATCGGTTGGTTGTCGGGAATT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTATATTCTGACCGTGCTTTTCGGTTCTTACGTAGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGGATGCAATATTGCATCCCTCGCACAACCTCACAAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TCCGCAATATAAGGGTATCTCTCTAAAAAATGAAGGTGGAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGCTATCGGCGGGTGTGGCCTTTTCATCCTGAGTGGTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GACATTTGGGCTATCTGCGGCTGACTTAGGAATAGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TATCATGTCACCACCTCGCCAGCAGTAATCCTAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTATCATGCAAAATAATTTTAGATTTCTTGCTTGTAGCTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGATTTAATTTTGTGCCATCGCTCAATTCCTTGGGAACA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAATAAGCAAGCGTGCTATCCTCGCTTACTAGCATCT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTAAAGCCAATATAGACAGCAGTGTTGATATGTTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAGTTGTAGAGCGTAGTCAAATAGCTCCTCAATC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CATTCTAGAAAGAAAGATTCCATAAGAGAAGAAAAAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTTTCTCAATTCCGGATGCTGATTGGTTTGGGAAAGTTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAAACCTGTGACAATCGGGCTGGCAGGCTTTTGTGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTCAAAATAATCTCCATATTCTTGTTTGAAGTCTTCAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTACAGGTGCGGTAGGTTCAGCAGGTGTTTGAGATGC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGGAAACATGGCGCACGGCGAAATCGTGATTATTGATGGAGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCTAAATCAACTTTAATTCGGGTAATATTGTTCTC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTTGGTTGTTCTTTCATTGTTGCGACGATACAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AACCTTAGAAGCGTCTGCCTTGATGCGAATAGCCCAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AAGTTAAGGCATGGTGCGATCGCATCTATAATCTAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATTTTGACCATGAAGCGGACACATATTTGAATAGTTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AATCCCCTGCGCTGGCACACCTTTATTGTGTCCC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ACTGTTGCTGCAACTGGCACGGGCTTCGGTGTTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCTAGACTATATGTAAACAAAGCTTACTATCCATTAGGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTCCCGCTCTTAAAGGACTTGCTGAGGAAGCCAAGAAATTAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCCCATCAGGGATAGAGACTCCAAACCAATCGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TCAGAGGTTAATATGTCGATGTCGAACATTAATAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TACCTATACAAAGTACCATCAATCTGGTATAGATCTTGGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GCACAATTGCTTGGTCTTCCTAATAACATCATTGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AATTGGGAATACGGCTTATATAGAAATATGGAAAATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GCGACTTCTCTTAATCGCTTGCCTTGGCCACTGACAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GGTAATTATCCAAATCCTACAATTTTGAATAATGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATGCCCTTCACCGAAGTAGCACTAGCTATGTAATATTGAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCAAGAATTATTTCAAGAACAATTATGCGATCGCTG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AATACTAGGTTATAGATGTCTGCATATTTTCTAACGCA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAGAGAAGCAGGTAATTGAACACATAAGGAAGATAGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATATATAGTGTCATCGTGCTATTATTAAAAATAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GAACGATTTGAGTCTTGGCGAGTACATCCAGAAGAAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATTGTCGATGGCATTGTCGTTCGTGATGGGTTCCGATCC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GATGAATTAATCTATAATATAAGAAGTTAAGAAAATAGAGGGCAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TCGGCTTTACCAACTTCTTCACTTCTTCCTGATCGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGTGGGGGCTTCCTCTGTTTTAGCTGTTTCAACTTCAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAGTAATTAAAACATGAGTGTCCCCCCAAAAGTTAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATTTTTTGTTTTCAAAAATACTTTAAACAAGGTATTGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTGTGCGTCAGTTTGCATTGGATTTAGGGGTAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AAGGAATCCAAGCAAGCCGCCCACCTTCATCTCCAAATT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AAATTCAGGTGTCCTAATAATCATATACATAGCGTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTCATCTCTGCATCTCCTTTGCTTTGGTTGTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTGCTAATAATGACTTCACAGGCGTGATCGCTGGTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTAGAAATACCCCATTTGGTTTGTTGAAATCTCTGATTTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTCCCAATGTTTGCAAAAGTTTGAGTTAATGCCC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGGATGAGTTTTAAAATTCTCGGATGTCCGTTTTCAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GGGTGATGTAGATCCGACTGAGGATAATTTCTTAAAACT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATAAAATAGCGGTGATGTTTTAGATAGTCTCTTTAGGGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTGGGTAAATCCTTAGTAATGATTGCTGGGATTATGGAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCTAAAGGTACAGTTACCGTCGAAACTGTAAAAGAAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGTGCATGAAGATTTACCCGTTGATTTCCACCTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGGGTTGTAACCAGTTATCAGAAGCCCAGTCAGATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GGAAAACCACAAACAGATTGCAGCAGCGATCGCCA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTAAGAGAAAAAGAAGCAAAGAGCTTTATTGCTCAGTTGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTATTAAAAACAGTTGGAAAACCGCTGATATAACAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATCTCAGGGGCATTTTGACAACAAACTTTCTACTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGGGATTGCTTACCCAAGCCGATATAGATTTATTTTCTATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AACTTTACAAAATCAATCTATTAGCAGCTTAGTAGATGCT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGAAGAAAGGAGAATCAATCCAAGATTCAGGAAGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ACGGCAAGTTAAATTTCATCCCCAAGAAATTAGTAGGGTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTAGCTAACATCCTTTCTCAAAGTGTAGAATCCG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC

>NC_019771|18|5|4752371-4758593|CRT
GTTTTAGTCCCCTTGCGGGGATTAGTTATGTGGAAAC	TGACGCTGGAGATAAGGCAGTTTACAAAGCTCAAACAGGAGG
GTTTCAATCCCCTTGCGGGGATTATTTATTTGGAAAC	TAAAAGCCTATAAGCGTGTATCAATACACTGCAATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATAGAATATGCCAAACCCTTGGGGAATCCCTGAAATAGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGGTTGTCTCCAGCCGGACACCTCCCACCTATACAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTGCTATTTATTTCTGAATCGGCTGAGGTTGAAGATGC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ACCTGACGCTTTCCTAAGTAATCCACCTCAATCCCT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGAAAATCTTGTCAATCCACTCAAAAGGAATCCAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGTCGCCACTTGTCCTGAACCCATGCAGCAGAAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTATCATGCAAAATAATTTTAGATTTCTTGCTTGTAGCTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTCAAAATAATCTCCATATTCTTGTTTGAAGTCTTCAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTGACTTGCTTCTCGGATTGGTTAGCAATTTGACTTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATCCCTGGAACTGATTCTTCCTGATATTGCCATCCG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGAGTGGATAGTTTCTATAAAAACAATCGGGGAAAGAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTGGACGACGGATTTTAACCTCGTCGTTAACTTCAAATG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGTGGGGATAATCGGTTGGTTGTCGGGAATT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTATATTCTGACCGTGCTTTTCGGTTCTTACGTAGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGGATGCAATATTGCATCCCTCGCACAACCTCACAAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TCCGCAATATAAGGGTATCTCTCTAAAAAATGAAGGTGGAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGCTATCGGCGGGTGTGGCCTTTTCATCCTGAGTGGTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GACATTTGGGCTATCTGCGGCTGACTTAGGAATAGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TATCATGTCACCACCTCGCCAGCAGTAATCCTAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTATCATGCAAAATAATTTTAGATTTCTTGCTTGTAGCTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGATTTAATTTTGTGCCATCGCTCAATTCCTTGGGAACA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAATAAGCAAGCGTGCTATCCTCGCTTACTAGCATCT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTAAAGCCAATATAGACAGCAGTGTTGATATGTTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAGTTGTAGAGCGTAGTCAAATAGCTCCTCAATC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CATTCTAGAAAGAAAGATTCCATAAGAGAAGAAAAAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTTTCTCAATTCCGGATGCTGATTGGTTTGGGAAAGTTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAAACCTGTGACAATCGGGCTGGCAGGCTTTTGTGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTCAAAATAATCTCCATATTCTTGTTTGAAGTCTTCAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTACAGGTGCGGTAGGTTCAGCAGGTGTTTGAGATGC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGGAAACATGGCGCACGGCGAAATCGTGATTATTGATGGAGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCTAAATCAACTTTAATTCGGGTAATATTGTTCTC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTTGGTTGTTCTTTCATTGTTGCGACGATACAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AACCTTAGAAGCGTCTGCCTTGATGCGAATAGCCCAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AAGTTAAGGCATGGTGCGATCGCATCTATAATCTAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATTTTGACCATGAAGCGGACACATATTTGAATAGTTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AATCCCCTGCGCTGGCACACCTTTATTGTGTCCC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ACTGTTGCTGCAACTGGCACGGGCTTCGGTGTTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCTAGACTATATGTAAACAAAGCTTACTATCCATTAGGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTCCCGCTCTTAAAGGACTTGCTGAGGAAGCCAAGAAATTAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCCCATCAGGGATAGAGACTCCAAACCAATCGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TCAGAGGTTAATATGTCGATGTCGAACATTAATAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TACCTATACAAAGTACCATCAATCTGGTATAGATCTTGGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GCACAATTGCTTGGTCTTCCTAATAACATCATTGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AATTGGGAATACGGCTTATATAGAAATATGGAAAATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GCGACTTCTCTTAATCGCTTGCCTTGGCCACTGACAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GGTAATTATCCAAATCCTACAATTTTGAATAATGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATGCCCTTCACCGAAGTAGCACTAGCTATGTAATATTGAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCAAGAATTATTTCAAGAACAATTATGCGATCGCTG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AATACTAGGTTATAGATGTCTGCATATTTTCTAACGCA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAGAGAAGCAGGTAATTGAACACATAAGGAAGATAGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATATATAGTGTCATCGTGCTATTATTAAAAATAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GAACGATTTGAGTCTTGGCGAGTACATCCAGAAGAAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATTGTCGATGGCATTGTCGTTCGTGATGGGTTCCGATCC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GATGAATTAATCTATAATATAAGAAGTTAAGAAAATAGAGGGCAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TCGGCTTTACCAACTTCTTCACTTCTTCCTGATCGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGTGGGGGCTTCCTCTGTTTTAGCTGTTTCAACTTCAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAGTAATTAAAACATGAGTGTCCCCCCAAAAGTTAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATTTTTTGTTTTCAAAAATACTTTAAACAAGGTATTGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTGTGCGTCAGTTTGCATTGGATTTAGGGGTAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AAGGAATCCAAGCAAGCCGCCCACCTTCATCTCCAAATT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AAATTCAGGTGTCCTAATAATCATATACATAGCGTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTCATCTCTGCATCTCCTTTGCTTTGGTTGTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTGCTAATAATGACTTCACAGGCGTGATCGCTGGTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTAGAAATACCCCATTTGGTTTGTTGAAATCTCTGATTTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTCCCAATGTTTGCAAAAGTTTGAGTTAATGCCC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGGATGAGTTTTAAAATTCTCGGATGTCCGTTTTCAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GGGTGATGTAGATCCGACTGAGGATAATTTCTTAAAACT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATAAAATAGCGGTGATGTTTTAGATAGTCTCTTTAGGGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTGGGTAAATCCTTAGTAATGATTGCTGGGATTATGGAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCTAAAGGTACAGTTACCGTCGAAACTGTAAAAGAAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGTGCATGAAGATTTACCCGTTGATTTCCACCTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGGGTTGTAACCAGTTATCAGAAGCCCAGTCAGATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GGAAAACCACAAACAGATTGCAGCAGCGATCGCCA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTAAGAGAAAAAGAAGCAAAGAGCTTTATTGCTCAGTTGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTATTAAAAACAGTTGGAAAACCGCTGATATAACAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATCTCAGGGGCATTTTGACAACAAACTTTCTACTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGGGATTGCTTACCCAAGCCGATATAGATTTATTTTCTATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AACTTTACAAAATCAATCTATTAGCAGCTTAGTAGATGCT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGAAGAAAGGAGAATCAATCCAAGATTCAGGAAGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ACGGCAAGTTAAATTTCATCCCCAAGAAATTAGTAGGGTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTAGCTAACATCCTTTCTCAAAGTGTAGAATCCG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC

>NC_019771|18|6|4752450-4753596|PILER-CR
GTTTCAATCCCCTTGCGGGGATTATTTATTTGGAAAC	TAAAAGCCTATAAGCGTGTATCAATACACTGCAATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATAGAATATGCCAAACCCTTGGGGAATCCCTGAAATAGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGGTTGTCTCCAGCCGGACACCTCCCACCTATACAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTGCTATTTATTTCTGAATCGGCTGAGGTTGAAGATGC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ACCTGACGCTTTCCTAAGTAATCCACCTCAATCCCT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGAAAATCTTGTCAATCCACTCAAAAGGAATCCAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGTCGCCACTTGTCCTGAACCCATGCAGCAGAAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTATCATGCAAAATAATTTTAGATTTCTTGCTTGTAGCTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTCAAAATAATCTCCATATTCTTGTTTGAAGTCTTCAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTGACTTGCTTCTCGGATTGGTTAGCAATTTGACTTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATCCCTGGAACTGATTCTTCCTGATATTGCCATCCG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGAGTGGATAGTTTCTATAAAAACAATCGGGGAAAGAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTGGACGACGGATTTTAACCTCGTCGTTAACTTCAAATG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGTGGGGATAATCGGTTGGTTGTCGGGAATT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTATATTCTGACCGTGCTTTTCGGTTCTTACGTAGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCAGGGATGCAATATTGCATCCCTCGCACAACCTCACAAAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTCCGCAATATAAGGGTATCTCTCTAAAAAATGAAGGTGGACGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGCTATCGGCGGGTGTGGCCTTTTCATCCTGAGTGGTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GACATTTGGGCTATCTGCGGCTGACTTAGGAATAGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TATCATGTCACCACCTCGCCAGCAGTAATCCTAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTATCATGCAAAATAATTTTAGATTTCTTGCTTGTAGCTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGATTTAATTTTGTGCCATCGCTCAATTCCTTGGGAACA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAATAAGCAAGCGTGCTATCCTCGCTTACTAGCATCT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTAAAGCCAATATAGACAGCAGTGTTGATATGTTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAGTTGTAGAGCGTAGTCAAATAGCTCCTCAATC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CATTCTAGAAAGAAAGATTCCATAAGAGAAGAAAAAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTTTCTCAATTCCGGATGCTGATTGGTTTGGGAAAGTTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAAACCTGTGACAATCGGGCTGGCAGGCTTTTGTGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTCAAAATAATCTCCATATTCTTGTTTGAAGTCTTCAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTACAGGTGCGGTAGGTTCAGCAGGTGTTTGAGATGC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGGAAACATGGCGCACGGCGAAATCGTGATTATTGATGGAGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCTAAATCAACTTTAATTCGGGTAATATTGTTCTC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTTGGTTGTTCTTTCATTGTTGCGACGATACAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AACCTTAGAAGCGTCTGCCTTGATGCGAATAGCCCAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AAGTTAAGGCATGGTGCGATCGCATCTATAATCTAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATTTTGACCATGAAGCGGACACATATTTGAATAGTTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AATCCCCTGCGCTGGCACACCTTTATTGTGTCCC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ACTGTTGCTGCAACTGGCACGGGCTTCGGTGTTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCTAGACTATATGTAAACAAAGCTTACTATCCATTAGGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTCCCGCTCTTAAAGGACTTGCTGAGGAAGCCAAGAAATTAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCCCATCAGGGATAGAGACTCCAAACCAATCGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TCAGAGGTTAATATGTCGATGTCGAACATTAATAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TACCTATACAAAGTACCATCAATCTGGTATAGATCTTGGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GCACAATTGCTTGGTCTTCCTAATAACATCATTGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AATTGGGAATACGGCTTATATAGAAATATGGAAAATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GCGACTTCTCTTAATCGCTTGCCTTGGCCACTGACAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GGTAATTATCCAAATCCTACAATTTTGAATAATGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATGCCCTTCACCGAAGTAGCACTAGCTATGTAATATTGAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCAAGAATTATTTCAAGAACAATTATGCGATCGCTG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AATACTAGGTTATAGATGTCTGCATATTTTCTAACGCA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAGAGAAGCAGGTAATTGAACACATAAGGAAGATAGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATATATAGTGTCATCGTGCTATTATTAAAAATAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GAACGATTTGAGTCTTGGCGAGTACATCCAGAAGAAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACATTGTCGATGGCATTGTCGTTCGTGATGGGTTCCGATCCGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GATGAATTAATCTATAATATAAGAAGTTAAGAAAATAGAGGGCAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TCGGCTTTACCAACTTCTTCACTTCTTCCTGATCGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGTGGGGGCTTCCTCTGTTTTAGCTGTTTCAACTTCAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAGTAATTAAAACATGAGTGTCCCCCCAAAAGTTAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATTTTTTGTTTTCAAAAATACTTTAAACAAGGTATTGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTGTGCGTCAGTTTGCATTGGATTTAGGGGTAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AAGGAATCCAAGCAAGCCGCCCACCTTCATCTCCAAATT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AAATTCAGGTGTCCTAATAATCATATACATAGCGTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTCATCTCTGCATCTCCTTTGCTTTGGTTGTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTGCTAATAATGACTTCACAGGCGTGATCGCTGGTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTAGAAATACCCCATTTGGTTTGTTGAAATCTCTGATTTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTCCCAATGTTTGCAAAAGTTTGAGTTAATGCCC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGGATGAGTTTTAAAATTCTCGGATGTCCGTTTTCAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GGGTGATGTAGATCCGACTGAGGATAATTTCTTAAAACT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATAAAATAGCGGTGATGTTTTAGATAGTCTCTTTAGGGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTGGGTAAATCCTTAGTAATGATTGCTGGGATTATGGAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCTAAAGGTACAGTTACCGTCGAAACTGTAAAAGAAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGTGCATGAAGATTTACCCGTTGATTTCCACCTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGGGTTGTAACCAGTTATCAGAAGCCCAGTCAGATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GGAAAACCACAAACAGATTGCAGCAGCGATCGCCA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTAAGAGAAAAAGAAGCAAAGAGCTTTATTGCTCAGTTGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTATTAAAAACAGTTGGAAAACCGCTGATATAACAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATCTCAGGGGCATTTTGACAACAAACTTTCTACTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGGGATTGCTTACCCAAGCCGATATAGATTTATTTTCTATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AACTTTACAAAATCAATCTATTAGCAGCTTAGTAGATGCT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGAAGAAAGGAGAATCAATCCAAGATTCAGGAAGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ACGGCAAGTTAAATTTCATCCCCAAGAAATTAGTAGGGTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTAGCTAACATCCTTTCTCAAAGTGTAGAATCCG


>NC_019771|18|7|4753715-4756422|PILER-CR
	TAAAAGCCTATAAGCGTGTATCAATACACTGCAATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATAGAATATGCCAAACCCTTGGGGAATCCCTGAAATAGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGGTTGTCTCCAGCCGGACACCTCCCACCTATACAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTGCTATTTATTTCTGAATCGGCTGAGGTTGAAGATGC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ACCTGACGCTTTCCTAAGTAATCCACCTCAATCCCT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGAAAATCTTGTCAATCCACTCAAAAGGAATCCAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGTCGCCACTTGTCCTGAACCCATGCAGCAGAAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTATCATGCAAAATAATTTTAGATTTCTTGCTTGTAGCTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTCAAAATAATCTCCATATTCTTGTTTGAAGTCTTCAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTGACTTGCTTCTCGGATTGGTTAGCAATTTGACTTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATCCCTGGAACTGATTCTTCCTGATATTGCCATCCG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGAGTGGATAGTTTCTATAAAAACAATCGGGGAAAGAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTGGACGACGGATTTTAACCTCGTCGTTAACTTCAAATG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGTGGGGATAATCGGTTGGTTGTCGGGAATT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTATATTCTGACCGTGCTTTTCGGTTCTTACGTAGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCAGGGATGCAATATTGCATCCCTCGCACAACCTCACAAAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTCCGCAATATAAGGGTATCTCTCTAAAAAATGAAGGTGGACGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGCTATCGGCGGGTGTGGCCTTTTCATCCTGAGTGGTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GACATTTGGGCTATCTGCGGCTGACTTAGGAATAGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TATCATGTCACCACCTCGCCAGCAGTAATCCTAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTATCATGCAAAATAATTTTAGATTTCTTGCTTGTAGCTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGATTTAATTTTGTGCCATCGCTCAATTCCTTGGGAACA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAATAAGCAAGCGTGCTATCCTCGCTTACTAGCATCT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTAAAGCCAATATAGACAGCAGTGTTGATATGTTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAGTTGTAGAGCGTAGTCAAATAGCTCCTCAATC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CATTCTAGAAAGAAAGATTCCATAAGAGAAGAAAAAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTTTCTCAATTCCGGATGCTGATTGGTTTGGGAAAGTTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAAACCTGTGACAATCGGGCTGGCAGGCTTTTGTGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTCAAAATAATCTCCATATTCTTGTTTGAAGTCTTCAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTACAGGTGCGGTAGGTTCAGCAGGTGTTTGAGATGC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGGAAACATGGCGCACGGCGAAATCGTGATTATTGATGGAGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCTAAATCAACTTTAATTCGGGTAATATTGTTCTC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTTGGTTGTTCTTTCATTGTTGCGACGATACAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AACCTTAGAAGCGTCTGCCTTGATGCGAATAGCCCAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AAGTTAAGGCATGGTGCGATCGCATCTATAATCTAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATTTTGACCATGAAGCGGACACATATTTGAATAGTTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AATCCCCTGCGCTGGCACACCTTTATTGTGTCCC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ACTGTTGCTGCAACTGGCACGGGCTTCGGTGTTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCTAGACTATATGTAAACAAAGCTTACTATCCATTAGGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTCCCGCTCTTAAAGGACTTGCTGAGGAAGCCAAGAAATTAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCCCATCAGGGATAGAGACTCCAAACCAATCGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TCAGAGGTTAATATGTCGATGTCGAACATTAATAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TACCTATACAAAGTACCATCAATCTGGTATAGATCTTGGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GCACAATTGCTTGGTCTTCCTAATAACATCATTGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AATTGGGAATACGGCTTATATAGAAATATGGAAAATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GCGACTTCTCTTAATCGCTTGCCTTGGCCACTGACAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GGTAATTATCCAAATCCTACAATTTTGAATAATGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATGCCCTTCACCGAAGTAGCACTAGCTATGTAATATTGAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCAAGAATTATTTCAAGAACAATTATGCGATCGCTG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AATACTAGGTTATAGATGTCTGCATATTTTCTAACGCA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAGAGAAGCAGGTAATTGAACACATAAGGAAGATAGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATATATAGTGTCATCGTGCTATTATTAAAAATAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GAACGATTTGAGTCTTGGCGAGTACATCCAGAAGAAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACATTGTCGATGGCATTGTCGTTCGTGATGGGTTCCGATCCGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GATGAATTAATCTATAATATAAGAAGTTAAGAAAATAGAGGGCAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TCGGCTTTACCAACTTCTTCACTTCTTCCTGATCGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGTGGGGGCTTCCTCTGTTTTAGCTGTTTCAACTTCAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAGTAATTAAAACATGAGTGTCCCCCCAAAAGTTAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATTTTTTGTTTTCAAAAATACTTTAAACAAGGTATTGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTGTGCGTCAGTTTGCATTGGATTTAGGGGTAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AAGGAATCCAAGCAAGCCGCCCACCTTCATCTCCAAATT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AAATTCAGGTGTCCTAATAATCATATACATAGCGTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTCATCTCTGCATCTCCTTTGCTTTGGTTGTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTGCTAATAATGACTTCACAGGCGTGATCGCTGGTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTAGAAATACCCCATTTGGTTTGTTGAAATCTCTGATTTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTCCCAATGTTTGCAAAAGTTTGAGTTAATGCCC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGGATGAGTTTTAAAATTCTCGGATGTCCGTTTTCAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GGGTGATGTAGATCCGACTGAGGATAATTTCTTAAAACT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATAAAATAGCGGTGATGTTTTAGATAGTCTCTTTAGGGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTGGGTAAATCCTTAGTAATGATTGCTGGGATTATGGAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCTAAAGGTACAGTTACCGTCGAAACTGTAAAAGAAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGTGCATGAAGATTTACCCGTTGATTTCCACCTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGGGTTGTAACCAGTTATCAGAAGCCCAGTCAGATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GGAAAACCACAAACAGATTGCAGCAGCGATCGCCA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTAAGAGAAAAAGAAGCAAAGAGCTTTATTGCTCAGTTGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTATTAAAAACAGTTGGAAAACCGCTGATATAACAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATCTCAGGGGCATTTTGACAACAAACTTTCTACTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGGGATTGCTTACCCAAGCCGATATAGATTTATTTTCTATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AACTTTACAAAATCAATCTATTAGCAGCTTAGTAGATGCT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGAAGAAAGGAGAATCAATCCAAGATTCAGGAAGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ACGGCAAGTTAAATTTCATCCCCAAGAAATTAGTAGGGTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTAGCTAACATCCTTTCTCAAAGTGTAGAATCCG


>NC_019771|18|8|4756462-4758593|PILER-CR
	TAAAAGCCTATAAGCGTGTATCAATACACTGCAATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATAGAATATGCCAAACCCTTGGGGAATCCCTGAAATAGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGGTTGTCTCCAGCCGGACACCTCCCACCTATACAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTGCTATTTATTTCTGAATCGGCTGAGGTTGAAGATGC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ACCTGACGCTTTCCTAAGTAATCCACCTCAATCCCT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGAAAATCTTGTCAATCCACTCAAAAGGAATCCAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGTCGCCACTTGTCCTGAACCCATGCAGCAGAAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTATCATGCAAAATAATTTTAGATTTCTTGCTTGTAGCTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTCAAAATAATCTCCATATTCTTGTTTGAAGTCTTCAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTGACTTGCTTCTCGGATTGGTTAGCAATTTGACTTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATCCCTGGAACTGATTCTTCCTGATATTGCCATCCG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGAGTGGATAGTTTCTATAAAAACAATCGGGGAAAGAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTGGACGACGGATTTTAACCTCGTCGTTAACTTCAAATG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGTGGGGATAATCGGTTGGTTGTCGGGAATT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTATATTCTGACCGTGCTTTTCGGTTCTTACGTAGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACCAGGGATGCAATATTGCATCCCTCGCACAACCTCACAAAAGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACTCCGCAATATAAGGGTATCTCTCTAAAAAATGAAGGTGGACGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGCTATCGGCGGGTGTGGCCTTTTCATCCTGAGTGGTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GACATTTGGGCTATCTGCGGCTGACTTAGGAATAGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TATCATGTCACCACCTCGCCAGCAGTAATCCTAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTATCATGCAAAATAATTTTAGATTTCTTGCTTGTAGCTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGATTTAATTTTGTGCCATCGCTCAATTCCTTGGGAACA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAATAAGCAAGCGTGCTATCCTCGCTTACTAGCATCT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTAAAGCCAATATAGACAGCAGTGTTGATATGTTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAGTTGTAGAGCGTAGTCAAATAGCTCCTCAATC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CATTCTAGAAAGAAAGATTCCATAAGAGAAGAAAAAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTTTCTCAATTCCGGATGCTGATTGGTTTGGGAAAGTTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAAACCTGTGACAATCGGGCTGGCAGGCTTTTGTGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTCAAAATAATCTCCATATTCTTGTTTGAAGTCTTCAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTACAGGTGCGGTAGGTTCAGCAGGTGTTTGAGATGC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGGAAACATGGCGCACGGCGAAATCGTGATTATTGATGGAGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCTAAATCAACTTTAATTCGGGTAATATTGTTCTC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTTGGTTGTTCTTTCATTGTTGCGACGATACAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AACCTTAGAAGCGTCTGCCTTGATGCGAATAGCCCAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AAGTTAAGGCATGGTGCGATCGCATCTATAATCTAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATTTTGACCATGAAGCGGACACATATTTGAATAGTTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AATCCCCTGCGCTGGCACACCTTTATTGTGTCCC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ACTGTTGCTGCAACTGGCACGGGCTTCGGTGTTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCTAGACTATATGTAAACAAAGCTTACTATCCATTAGGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTCCCGCTCTTAAAGGACTTGCTGAGGAAGCCAAGAAATTAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCCCATCAGGGATAGAGACTCCAAACCAATCGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TCAGAGGTTAATATGTCGATGTCGAACATTAATAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TACCTATACAAAGTACCATCAATCTGGTATAGATCTTGGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GCACAATTGCTTGGTCTTCCTAATAACATCATTGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AATTGGGAATACGGCTTATATAGAAATATGGAAAATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GCGACTTCTCTTAATCGCTTGCCTTGGCCACTGACAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GGTAATTATCCAAATCCTACAATTTTGAATAATGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATGCCCTTCACCGAAGTAGCACTAGCTATGTAATATTGAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCAAGAATTATTTCAAGAACAATTATGCGATCGCTG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AATACTAGGTTATAGATGTCTGCATATTTTCTAACGCA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAGAGAAGCAGGTAATTGAACACATAAGGAAGATAGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATATATAGTGTCATCGTGCTATTATTAAAAATAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GAACGATTTGAGTCTTGGCGAGTACATCCAGAAGAAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAACATTGTCGATGGCATTGTCGTTCGTGATGGGTTCCGATCCGTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GATGAATTAATCTATAATATAAGAAGTTAAGAAAATAGAGGGCAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TCGGCTTTACCAACTTCTTCACTTCTTCCTGATCGT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGTGGGGGCTTCCTCTGTTTTAGCTGTTTCAACTTCAC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TAGTAATTAAAACATGAGTGTCCCCCCAAAAGTTAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATTTTTTGTTTTCAAAAATACTTTAAACAAGGTATTGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTGTGCGTCAGTTTGCATTGGATTTAGGGGTAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AAGGAATCCAAGCAAGCCGCCCACCTTCATCTCCAAATT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AAATTCAGGTGTCCTAATAATCATATACATAGCGTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTCATCTCTGCATCTCCTTTGCTTTGGTTGTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTGCTAATAATGACTTCACAGGCGTGATCGCTGGTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CTAGAAATACCCCATTTGGTTTGTTGAAATCTCTGATTTAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTCCCAATGTTTGCAAAAGTTTGAGTTAATGCCC
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TGGATGAGTTTTAAAATTCTCGGATGTCCGTTTTCAAA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GGGTGATGTAGATCCGACTGAGGATAATTTCTTAAAACT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATAAAATAGCGGTGATGTTTTAGATAGTCTCTTTAGGGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTGGGTAAATCCTTAGTAATGATTGCTGGGATTATGGAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CCTAAAGGTACAGTTACCGTCGAAACTGTAAAAGAAAT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGTGCATGAAGATTTACCCGTTGATTTCCACCTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGGGTTGTAACCAGTTATCAGAAGCCCAGTCAGATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	GGAAAACCACAAACAGATTGCAGCAGCGATCGCCA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTAAGAGAAAAAGAAGCAAAGAGCTTTATTGCTCAGTTGA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTTATTAAAAACAGTTGGAAAACCGCTGATATAACAG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ATCTCAGGGGCATTTTGACAACAAACTTTCTACTTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CGGGATTGCTTACCCAAGCCGATATAGATTTATTTTCTATA
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	AACTTTACAAAATCAATCTATTAGCAGCTTAGTAGATGCT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	CAGGAAGAAAGGAGAATCAATCCAAGATTCAGGAAGG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	ACGGCAAGTTAAATTTCATCCCCAAGAAATTAGTAGGGTT
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC	TTAGCTAACATCCTTTCTCAAAGTGTAGAATCCG
GTTTCAGTCCCCTTGCGGGGATTATTTATTTGGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015216199.1\|4764692_4765916_+\|CRISPR-associated-RAMP-protein-Csx10	csx10gr5	cd09700_csx10gr5_CAS-III-D	gnl\|CDD\|131722
NC_019771.1\|WP_042466116.1\|4737670_4738051_+\|response-regulator	unknown	unknown	gnl\|CDD\|381104
NC_019771.1\|WP_015216192.1\|4750668_4751052_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|350353
NC_019771.1\|WP_015216191.1\|4746175_4747195_-\|dihydroorotate-dehydrogenase-like-protein	unknown	unknown	gnl\|CDD\|236051
NC_019771.1\|WP_015216189.1\|4739716_4742158_+\|phosphoenolpyruvate-synthase	unknown	unknown	gnl\|CDD\|235809
NC_019771.1\|WP_015216202.1\|4767548_4768115_+\|Uma2-family-endonuclease	unknown	unknown	gnl\|CDD\|368559
NC_019771.1\|WP_015216203.1\|4768139_4769006_+\|CRISPR-associated-RAMP-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187814
NC_019771.1\|WP_015216187.1\|4738793_4738973_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015216190.1\|4742517_4746009_+\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|237425
NC_019771.1\|WP_015216184.1\|4735185_4737567_+\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|274368
NC_019771.1\|WP_015216196.1\|4760771_4761692_+\|hypothetical-protein	csx3	mkCas0115_csx3_CAS-I:CAS-III	unknown
NC_019771.1\|WP_015216197.1\|4761688_4763986_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cls000742_cas10_CAS-III	gnl\|CDD\|274208
NC_019771.1\|WP_015216201.1\|4766355_4767483_+\|putative-CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	gnl\|CDD\|187873
NC_019771.1\|WP_015216183.1\|4733342_4735181_+\|response-regulator	unknown	unknown	gnl\|CDD\|223816
NC_019771.1\|WP_015216194.1\|4758973_4760302_-\|TIGR03985-family-CRISPR-associated-protein	WYL	mkCas0075_WYL_CAS-I:CAS-III	gnl\|CDD\|274901
NC_019771.1\|WP_015216200.1\|4765912_4766332_+\|hypothetical-protein	csm2gr11	mkCas0063_csm2gr11_CAS-III-D	unknown
NC_019771.1\|WP_015216195.1\|4760403_4760709_+\|hypothetical-protein	csx3	mkCas0115_csx3_CAS-I:CAS-III	gnl\|CDD\|187871
NC_019771.1\|WP_015216186.1\|4738206_4738581_+\|response-regulator	unknown	unknown	gnl\|CDD\|381104
NC_019771.1\|WP_015216198.1\|4763982_4764693_+\|DUF324-domain-containing-protein	csm3gr7	COG1337_csm3gr7_CAS-III-D	gnl\|CDD\|224256
NC_019771.1\|WP_015216193.1\|4751172_4752327_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl\|CDD\|227838

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_042466116.1\|4737670_4738051_+\|response-regulator	gnl\|CDD\|381104	cd17552, REC_RR468-like, phosphoacceptor receiver (REC) domain of Thermotoga maritima response regulator RR468 and similar domains. Thermotoga maritima RR468 (encoded by gene TM0468) is the cognate response regulator (RR) of the class I histidine kinase HK853 (product of gene TM0853). HK853/RR468 comprise a two-component system (TCS) that couples environmental stimuli to adaptive responses. This subfamily also includes Fremyella diplosiphon complementary adaptation response regulator homolog RcaF, a small RR that is involved in four-step phosphorelays of the complementary chromatic adaptation (CCA) system that occurs in many cyanobacteria. Both RR468 and RcaF are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	2.21746e-62
NC_019771.1\|WP_015216192.1\|4750668_4751052_+\|hypothetical-protein	gnl\|CDD\|350353	cd14503, PTP-bact, bacterial tyrosine-protein phosphataseS similar to Neisseria NMA1982. This subfamily is composed of bacterial tyrosine-protein phosphatases similar to Neisseria meningitidis NMA1982, which displays phosphatase activity but whose biological function is still unknown.	3.75887e-22
NC_019771.1\|WP_015216191.1\|4746175_4747195_-\|dihydroorotate-dehydrogenase-like-protein	gnl\|CDD\|236051	PRK07565, PRK07565, dihydroorotate dehydrogenase-like protein.	0
NC_019771.1\|WP_015216189.1\|4739716_4742158_+\|phosphoenolpyruvate-synthase	gnl\|CDD\|235809	PRK06464, PRK06464, phosphoenolpyruvate synthase; Validated.	0
NC_019771.1\|WP_015216202.1\|4767548_4768115_+\|Uma2-family-endonuclease	gnl\|CDD\|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	1.29609e-32
NC_019771.1\|WP_015216203.1\|4768139_4769006_+\|CRISPR-associated-RAMP-protein	gnl\|CDD\|187814	cd09683, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	7.20746e-78
NC_019771.1\|WP_015216190.1\|4742517_4746009_+\|PAS-domain-S-box-protein	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	3.96668e-82
NC_019771.1\|WP_015216184.1\|4735185_4737567_+\|PAS-domain-S-box-protein	gnl\|CDD\|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	6.84974e-58
NC_019771.1\|WP_015216199.1\|4764692_4765916_+\|CRISPR-associated-RAMP-protein-Csx10	gnl\|CDD\|131722	TIGR02674, cas_cyan_RAMP_2, CRISPR-associated RAMP protein, Csx10 family. CRISPR is a widespread repeat family in prokaryotes. At least 45 different protein families occur in prokaryotes only when these repeats are present. This family, a minor CRISPR-associated protein family, seems largely restricted to the Cyanobacteria. It belongs to the RAMP superfamily (pfam03787).	2.98868e-130
NC_019771.1\|WP_015216197.1\|4761688_4763986_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|274208	TIGR02577, thermophile-specific_DNA_repair_system, CRISPR-associated protein Cas10/Cmr2, subtype III-B. This model represent a Crm2 family of the CRISPR-associated RAMP module, a set of six genes recurring found together in prokaryotic genomes. This gene cluster is found only in species with CRISPR repeats, usually near the repeats themselves. Because most of the six (but not this family) contain RAMP domains, and because its appearance in a genome appears to depend on other CRISPR-associated Cas genes, the set is designated the CRISPR RAMP module. This protein, typified by TM1794 from Thermotoga maritima, is designated Crm2, for CRISPR RAMP Module protein 2.	2.96836e-37
NC_019771.1\|WP_015216201.1\|4766355_4767483_+\|putative-CRISPR-associated-protein	gnl\|CDD\|187873	cd09742, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems; also known as APE2256 family.	1.96793e-47
NC_019771.1\|WP_015216195.1\|4760403_4760709_+\|hypothetical-protein	gnl\|CDD\|187871	cd09740, Csx3_III-U, CRISPR/Cas system-associated protein Csx3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small protein in some cases fused to Csx1 (COG1517) family domains.	1.47563e-05
NC_019771.1\|WP_015216194.1\|4758973_4760302_-\|TIGR03985-family-CRISPR-associated-protein	gnl\|CDD\|274901	TIGR03985, hypothetical_protein_sll7078, CRISPR-associated protein, TIGR03985 family. Members of this protein family belong to CRISPR-associated (Cas) gene clusters. The majority of members are Cyanobacterial.	9.91921e-103
NC_019771.1\|WP_015216183.1\|4733342_4735181_+\|response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.47018e-77
NC_019771.1\|WP_015216186.1\|4738206_4738581_+\|response-regulator	gnl\|CDD\|381104	cd17552, REC_RR468-like, phosphoacceptor receiver (REC) domain of Thermotoga maritima response regulator RR468 and similar domains. Thermotoga maritima RR468 (encoded by gene TM0468) is the cognate response regulator (RR) of the class I histidine kinase HK853 (product of gene TM0853). HK853/RR468 comprise a two-component system (TCS) that couples environmental stimuli to adaptive responses. This subfamily also includes Fremyella diplosiphon complementary adaptation response regulator homolog RcaF, a small RR that is involved in four-step phosphorelays of the complementary chromatic adaptation (CCA) system that occurs in many cyanobacteria. Both RR468 and RcaF are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.02096e-61
NC_019771.1\|WP_015216198.1\|4763982_4764693_+\|DUF324-domain-containing-protein	gnl\|CDD\|224256	COG1337, COG1337, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	8.42931e-34
NC_019771.1\|WP_015216193.1\|4751172_4752327_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	4.50218e-56

>NC_019771.1|WP_015216193.1|4751172_4752327_-|CRISPR-associated-endoribonuclease-Cas6
MPRAATSSKRKTPSKNTSLVWADNTELVGLVFDLEATNSTSLYSQYTIGLHAWFLDQVRQINPDLSAYLHDSESEKPFNISALAGQLLPTGKQLQLQANQTLTWQINAISQPVVQFLSQWLTQLPPTLQLRDVHLQIKQVSIIHPPTTYSQLLQSSTKKHTNINLSFISPTSFRRKGHHFPLPVPVNLFHSYLRRWNDFSGIPVEQDAFLNWIDENVIIHQHRLESVKVAAGKRGSVTGFTGAISLGLSKSALANIEFTQLFYTLVQLAPYCGTGHKTTFGLGQTCLDWVEPKSNASSGTLTTLLGERIEELTAIFTAQRKRTGGDSEALRRNRTEKIAITWATILARREMGESLQVIAKDLEIPYITVKTYVKLARRALKDTQ
>NC_019771.1|WP_015216192.1|4750668_4751052_+|hypothetical-protein
MNVVRKINQELTICGQITPEQLQNLADDGYKSILNLRFADEQNSWNNEQEKTELLGLHYVNFPIKIENLNHESAIEVFQIISELPKPLLIHCDNSKCSAVIVLLYISTKQGIEFNQAWQQAVNLGLL
>NC_019771.1|WP_015216191.1|4746175_4747195_-|dihydroorotate-dehydrogenase-like-protein
MNLTTTYLGLELKSPLVPSASPLSQEIDNIKLMEDAGAGAVVMHSLFEEQLILEKYELHHHLTHGTESFAEALTYFPDITNFRIGPEEYLDHIRKAKEKVDIPIIASLNGFSVGGWTEYGKLIQEAGASALELNIYYVPTDPDLISQDIEQNYINILSAVKAAVTIPVAVKLSPYFTNTANMAKRLDDAGADGLVLFNRFYQPDINLETLEVEPHVLLSTPQAMRLPLRWIAILYGRINADLAATSGIHNAHDVLKMLMVGSNITMLCSVLMRHGIDHIRCIEQEMREWMEKHEYESVRQMQGSMSQLNCPNPSSFERAQYMRSLQTYNPEWGRIYIPS
>NC_019771.1|WP_015216190.1|4742517_4746009_+|PAS-domain-S-box-protein
MQFNEQLIDLPNLHQVIDRYPLTISVDSHVVDAIILMNQEHSNSLELINFSAVLPRHKSSQKETSYVLVVEETQLVGIFTLRDVLRLTAFGLDLSRTTMAEVMTKHPITLKNSEFQDISTAFLLLKQYQIHHLPIVDDGGELLGIITESSLLQQLDLVKIVGIAQATQQYLGKSINESPNDQQIERVVHNTQDLLQSRVEEQVAEEIKVTEELQQTLEEMQIFEEEIIQQNEQLGVAHEIAELERRRYQDLFQFTPYGYVVTDKLGLIQEANYAASLLLSVDQNYLIGKPITIFIGQPDRQNITSQLKNFQQFQEWEVELEPRHGESFPANVRISAMYDSQKQWCGWCWLLCNITERRQAEAALRRTSEQLEQKVAERIAELVIINQALQQEIIEHQQTELALRESEERFRQFGENIQAQIIWIKSCNSGATVYVNSAYEKIWGRSCQSLREQPLSWKEAIHPEDRDRILTEIDESHQKGESASLQYRIIQPNGEIRWIWGRCFPVQNQQGELEYCGSITEDITEYKQVEEERSKTQERLTLALEAANMGIWDWEIQTNQTLWSSNMGPIYGLPSHTLCPSPENFLYLIYPEDRNNFTKAVKLAIEQKTEFVSEHRVIWSDGSLHWLSARGKVYYDENDQPARMLGTTREISERKQAEQKIHEQAALLDIATDAIFVRDFQTEILFWNQGAEKIYGWQNHEAMGKNFRDIFYSTTSPQPEEVIALQTVVKSGTWHGELRRKTKFGQEIMVESRWTLMFDAEGQPKSILIVDTDITKKKELEEQFYRTQRLESIGTLAGGIAHDINNILTPILGAAQLLKGRLAHEQERHPLLLTIIENNAKRGAGLVKQVLSFARGLKGERAIVQVKHLIADVIQIGRQTFPKSIEFAAQISEDLWAVSGDTTQLHQVLMNLVVNARDAMPEGGCLQITAENLFIDETYTRMNFESKVGHHIVITITDTGIGMTPEILNRIFEPFFTTKEVGTGTGLGLSTVLGIIKSHDGFITVSSEVAKGSTFKIFLPSVEEPQIPAIEDLEMHSGQGELILVVDDEPQIRDVAKIILEQYNYQTITASNGIEAIALYAQHKKSISAVLMDMMMPEMDGITAIRTLQRMNPQVQVIACSGLSTIEVLPESANTEVQAVLFKPYTANDLLRNIDQIIRKAGV
>NC_019771.1|WP_015216189.1|4739716_4742158_+|phosphoenolpyruvate-synthase
MQKIQQNQENERPLSKEQALVLPFNTVGIADIPFVGGKNASLGEMIQQLSSKGVQVPTGFATTAYAYRFFISGAGLETKLRQIFADLDVEDIDNLRQCGKQARALMLDTPFPLELQQAIAQSYQILCQEYGEDTDVAVRSSATAEDLPDASFAGQQETYLNVHGIKGVLESCHKCFASIFTDRAISYRQNKGFDHFEVALSVGVQKMVRSDLACSGVMFSIDTETGFKDAALITAAYGLGETVVQGAVNPDEYLVFKPTLKQGFKPILQKRLGTKEIKMVYDLGGMKLTKNVSVLPSERHQFALNNGEILQLATWTSIIEDHYSQVRGMDTPMDIEWAKDGVTGELFIVQARPETVQSQKTKNVLRSYQLKEKGQIILTGRSVGEMIGQGKARVILDASQIQQFQAGDVLVTNRTDPDWEPIMKKASAIVTNSGGRTCHASIIAREMGIPAIVGCGNATTELQTGQEITVSCAEGETGKVYAGLLNFEINELPLENLPRTRTKIMMNVGNPEEALGLTAIPNDGVGLARMEFIIANHIKAHPLALLHFDDLEDELAKYKIAELTAQYENKAEFFIDKLAQGIGTIAAAFYPKPVIVRLSDFKSNEYANLLGGRQFEPKEENPMLGWRGASRYYDPRYREGFALECEAMKRVRNEMGLTNMILMVPFCRTPEEGRRVLAEMAANGLVKGENGLEVYVMCELPSNVILADEFSQVFDGFSIGSNDLTQLTLGLDRDSELVAHLFDERNSAVKRTIARAIATVKQFNRKIGICGQAPSDYPEFARFLVEEGIDSISLNPDSVLKTLLEIAAAEAVS
>NC_019771.1|WP_015216187.1|4738793_4738973_+|hypothetical-protein
MSNCICCSNKLLRHIRNHQVVLFCRNCWQEMPATNPKRAYSLSMSVPSHIGIKEFIATH
>NC_019771.1|WP_015216186.1|4738206_4738581_+|response-regulator
MTTRRILVVDDEEFIQEIVQSCFEDIAGWDVITASSGKEGLVKAMKEQPDAIVLDMMMPEMDGMTFLRYLKADPNIQSIPVVLITAKVDFTEPMRLLSLGVAGAIAKPFDPILLVDQVCNYLGW
>NC_019771.1|WP_042466116.1|4737670_4738051_+|response-regulator
MSIKCILVIDDEEVIQEVIQGCLEDIGEWEVITASSGKEGLLVAESKLPDGILLDVSMPEMDGLETLQKLQLHPVTQRIPVVLLTAKVQPADQARFSQLAVAGVIPKPFDPLILVDLVANAFHWDV
>NC_019771.1|WP_015216184.1|4735185_4737567_+|PAS-domain-S-box-protein
MKSAMNARIDQRFFPYIGAISSLAIAMLAVGTALFITWQLKSVLTNTIASFFFVAVAVSTWYGGLRLGLMTTILSVLTINYFFIPPIYNFTPATWNDFILLGLFFANSSIISLLSYDLQRSKKTLEQINQQLLGESTQRYASLAAAVPVGIFRTNLVGHCLYVNEQWCKITGMTFDQALGTGWVQALHPSDRDRIIQAWSQTTQNQEKSITVEFRFLRPDGVVTWVFTQAVVEQTNNGEVISYIGTVTDISESKQREEQLRLLESVIVTTNDAVLITAAEPIDLPGPKIVYVNPAFTQMTGYTSAEILGKTPRILQGEKTERAALDKIRANLQTWQPVQVEMINYRKDGSDFWVELNIIPVTDERGWFTHWIAIQRDITDRKQAETTLKLANVKLESRVALRTIELSQANAQLQLELKERQRAEVALRQSEAKFRSLSEFSPMGIFMNDAQGQCIYTNPRAQEIAGYTFAEALGFGWLEFVHPQDRKQITPQWIQAFSEQQGTVYEELRYVHKDGTIRYARVQSAPIFAENNKFIANVGTMEDITASRAIAQMKNEFISVVSHELRTPLTAIRGSLGLLAAGVYDKKPEKGKRMLQIASEQTDRLVRLVNDILDLGRLESGKMTLVMQSCDAATLIGKSVDAMQSSAEQNQITLSVNSPPSLQLWANPDAIIQTLTNLLSNAIKFSPPHTTIWINVECCEDIENVSGSSSPHSLVRFEVKDQGRGIPLDKLEAIFDRFQQVDASDSREKGGTGLGLAICRRIIQQHDGNIWAESTMGEGSSFYFTLKRTGNSE
>NC_019771.1|WP_015216183.1|4733342_4735181_+|response-regulator
MKILLVEDDQLTSSAITSNLIAHHYTVNLAIDGQAGLELATTYEYDLILLDLMLPKLDGISVCKQLRSQGYHSPILLLTAKDSTTDRVMGLDAGADDYMVKPCNIDELMARVRALLRRGKAIPSSVIVWENVYFDSVNSEVTCQDKLLHLTPKEYCLLELFLLNPKRIFSRSAILEKLWDFADTPGEETVSTHIKCLRQKLKAAGSSDPIETVHGLGYKLKPPSLLQASDTAVILSGNIQKPEKSYQQRVKSSTYKIWEKFKDKFAEQFAVLEQVSDLLAVEKLTPELQQQAQYQAHKLAGSLGIFGLIQGSEIARELENLLEPQIKIEELQSQQIFKLVKMLASEIHKKPELESKSDQISYSPLILIVDDDLILAERIRIEAIAWGLRVEIATDLDVARKAITQNPPNIVLLDLNFPSSTETGLTLLKQLTQQIPKIPVLTFTGKGNLTDRLEVASLGGCLFLQKPLPTYEILKAVTEILNRSQSKSAHRVMVVDDDLTALSHISSLLLPLGLEVIVLNNSKHFWDVLRDNNPDILVLDQEMPDFSGLDLCKVVRNDPKWYNLPIIFWSIHTKESDLDQAFTVGADDYISKSTDITELTTRIIRRLKRVEI
>NC_019771.1|WP_015216194.1|4758973_4760302_-|TIGR03985-family-CRISPR-associated-protein
MSEQNFSDLPQVELLQWLARGSLKQNLLRAVRLWVWLRSLYGDGQDQVLLNDGFTLADWKNTFFNSTHPKGEKIPQFHDPHCHCAKTTAEWLFDSHTGLNQEEWQHSLLSHIHITNLDEILQKRLFGITRRSLQADLQILEELGWLENREQKYHRVKHLPSRPITTKHNYNELYFLNQVDLEEIAENLSQKIAGVQRFFFKLDYVVTAIDKVENWQYELRKLWSQTPVPPIKLIYNSARLVESVECLVYPVCIYYVQRAVYLCAFGESPDRKTDWYNFRLDRIEDITPIAWTNPAIPKALQQRYQKRNLPNPEEIEVQMPKALGFDFYLESRLMLLRFDREYHDRYIQDTFRHETFNLISYQKAKSLIENSVINPEQKAELLKILANRSPKDAYYSLQYRHGDNNVTMRLRAWRPKVEILLPYDLRQKIAADITKEIGLYHI
>NC_019771.1|WP_015216195.1|4760403_4760709_+|hypothetical-protein
MTTYNIDLKDDILRVSFGEPAQNDQIVKDAATRLEEMSRLGELTGGQLLKINGPVSIPVAFVLAHKLSHIYGAIAFFDPKLGKYVISITHNPAYKLGDLID
>NC_019771.1|WP_015216196.1|4760771_4761692_+|hypothetical-protein
MNTYHINLDGDVLKVGFGATLTTGDEIVRDAAARLNEMIACGELPGGSLIKINGRTSVLVSQVLADKLSKLYDVIAFFDPKIGDKGLDRYVVTISKHPDYRVGDTFDVVRIQPQSSIKLVICGFANTGKTCFREGLKQALLQIPNAPASYVFSGCPDGDGSWFGETARRDADLAQKLKAEYKAGFTREFAEGKAQEVRGINTPIFVFDVGGKISDANRLIMGAATHAVILVKDVGDIAPWQELCKSLGLSVVAIIYSDYDGVNDVIAQETPILKGSVHRLKRGEDVSSRAIVRALANLLVSIEDKS
>NC_019771.1|WP_015216197.1|4761688_4763986_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MNNTIHPISIGIAWCLAWGNERQPQFDITVLREMCKALRNGGEVPAAVRTIVKQVEDLQGIDKDDFPETLEKLKNDYPDLWNQTTKIGLVYGGVTKVKQYVFESAKIQEVRGASGLLDRINLIDLPAFFNDKDVPQIYNAQCSDVRTWLNKNFHNTYKLSEVLISELIIYSTGGNILAFCPTAYVHDLADAIEKRYTHETLTANSCAVGDTFRLLEIRFGLLKEKIEDTPWLDWYQKNYQKPIVQAYFGFPKNENERLEVFQNRKSFNEITTKLAILFNQRRSGNIIPGRNTNRRYPVIFETHPYLVRDGSDRRSTIMRVGEGELPRETYFSEASVRKYLVGDRAKDGDTEEPKWYIDSKLEWRRGIFESWVKRFDRFLEKHDYLKTKYYGNLKPKDVEIPKTLTHVSNASNGFVAYIYADGNNMGGYIQKIRTPQKYKKFSLDVSDATEEAVFHAIAENLHPHVLKNYNNDEDHRFKNGDLVHPFEIITIGGDDIFIIVPANKALEISQMIGEKFEEIMIDKSDEKADYRIEANKPVDKRNIHRYQPQTAKNSECKLSTSIGVLITAVNTPIYYAKDLTEQLLKSAKEKAKKLKKVEYHGGTIDFLTLKSVSMIASNVKEFRSEALIIETSPKLRLYAAPYTLHEIGGLLKSIAALKKAKFPKSQLYQIRSLLERGKHTAILNYRYFRVRLKQGKAELKRDFEEVWCLPKDENNNGNLAPWMYESEEKIYETIWRDMVDIYEFVEEPESEESDKSENVTAGIES
>NC_019771.1|WP_015216198.1|4763982_4764693_+|DUF324-domain-containing-protein
MIKLEQITNSTQTKTITAIIDTALCIGAGGSSGSLADKPIVRNAEGNLLIPGSQLKGRLRHECEKIARGLKWDICYSPNPQTMCPQRAGLDGNFVREEYKISENDKNHHCLICQIFGNPVLPSRIIVDDLICEEDPDNLPEIIRPGVTINRRRRTSEESKLYFLETSPANTKLRFKGDIHLLNAPPYTAPLILAGLKHINALGGSKSAGLGWLTWELPDLSIAAEAWEFLAKGSRE
>NC_019771.1|WP_015216199.1|4764692_4765916_+|CRISPR-associated-RAMP-protein-Csx10
MKKISLEIKALSPLAIGQKKPGGNISEVEDCIPGSVIRGAVASQILKQTNQEIEPDDDFYKLFLGGNPAIFQNAYPGDDKIKSEVIVIPATALSSKIRPGFRTKGDGVFDTLIDRFCAENHGQIYDFNSPIEGNEVEGDRVDNFPGFYSRKSSKYSKNSAKTRLLTRVGINRRRATSEERVLYSIEVLNESKEQKKEAVIYTSTILAPDDLANTLQTFIHNHQDNFRLGGASSRGLGKVKMTVKPPQEIESKFNYQIDKFNQKLRKRWDEWGNIFGTVSDLPANRIYFTIDLQADAILTENWQRTTVISETMLQQFTGVKDSSLQLHTAYSSYDYRSGWNAAWGLMKDVELVTNRGGVYLFSTDNKDSWLQAWEDLEVYGIGDRTSEGFGQVQICNEFHLVLREEAV
>NC_019771.1|WP_015216200.1|4765912_4766332_+|hypothetical-protein
MSELSTQQQLKIQKAIRQAEDHLVTWIQDALDNRRSYGKLEESQFRNLVRVADTTESTEVIKNFLHYQVGRDEKWGRGQNSLAETIVSDINTRIKQKAKDIAKDAKSDDVNSIFLELTRRYLGYGARYLTYKLKGENQA
>NC_019771.1|WP_015216201.1|4766355_4767483_+|putative-CRISPR-associated-protein
MQRLVISTVGTSLLTNQIDREYEDGYYKRLRDTANCTSEEVKKYHEDVADIIEELKERAEEKLNSNDIDKIREASAELNGIYGLYTDQINQAEKDIHWLIASDTAQDKVTTEILKSFLTEQGLSISDYIPKGFSTISDEAFTQGIDELLNWFEDTIPGYQDSGYEIYFNLVGGFKAIQGFANTIGMFYADKITYIFEGSSELITIPRLPIKIDTKVIKPVEFTLMAQGAWINLEILEKVPETLLFIVDDKATLSTWGRLIWNRSKGDFLNGDLLEKLPYIKYETSFTKDYDSRKEKNERIKLQETLAKVSHLLIKSNGDTAPLKGDGGVLYEVYQNKGGIAHFRVTQGIRVSCTSSSGVLNLRRYGKEPEVNNNP
>NC_019771.1|WP_015216202.1|4767548_4768115_+|Uma2-family-endonuclease
MISTPVSTVTSLTDFLQLPETKTASEYIDGNIYQKPMPKGKHSAVQTFLAPAINQIATPKKIARAFTELRCTFEGRSIVPDISVFNWELIPLDDNGEIQNEFTIPPNWTIEILSPEQSSTRVINNILFCLKHGTELGWLIDPQERLIMTFLPNQLPEVKQNQDILPVLNSLTEWEISVEDIFSCLRLN
>NC_019771.1|WP_015216203.1|4768139_4769006_+|CRISPR-associated-RAMP-protein
MFDTFKNRLEITGKLTTITALRISAGRSTEPIGTDLPVIKDALGQPLIPGSSFKGALRSRLESFLRGIDSSFAEDPADFTSSARNKYVKDLKEQHKDNDEELTQKLVEMTDLISQLFGSPWIASKFQVRDLTVVPDTWFGQYQERDGVAIDRDTETAVNGKLYDFQVVPAGTQFQFRAVVENAEPWELGLLMIGLHQFETEQIPLGGGRSRGLGVVKLDISEMWWLDVNNNPKKLLTYLTELVNSRIGDKLPSYQEGKNFKDIWTQALIKHLTDDNISNNSITATQAQ

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Crispr_ID: NC_019771_19

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_19

5001036-5003639

Orphan

A:N

Consensus_repeat	Method
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	PILER-CR
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CRISPRCasFinder
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CRT

35 spacers

The CRISPR arrays of NC_019771_19

>merge|NC_019771|19|5001036-5003639|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATTCCTATTAGGGATTATTTGAAATTTCAACCCTTGATCAGTTTGAAAAGCTATTGCATCACCTTCTGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACGAGCCTAGGAAGCTCCCTAGCGTTGCGCTGCTGCCGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACTTTGTATGCAATTGGAATTACGTGGGACGCAGAGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACCACTACTCCAAGTGAAAAACGGTTGATAGAGGCAGCGAGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACCATTGTCCGACAGCATCATAGCTTTATTGAAAGCGTGATTGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACTGAGACATGGTTTGTGAGAGAACTGGAATTAAATGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACATCAAAGAAGAAAACGGTAATGCAATCTTAATTGTCGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACTCATTAAAATTAGCTTGTCGTATTGACGATAACGACAACGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACGCTCTCTACTCTTACGCACTAGATAAGTCTCCAATGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACAAAAGGTAGTTCGTTTGTATCAGTAAATCGTGATGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACTATGGTATTAATCAATTATCGCTTGGGGAAAATCGGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACAATCTCTCAAAATCTGAACCATTAATATATTATTGTGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACCTGACCTTATCCCCACCAGTCAAGCTGAGGAAACGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACGTTCGGTCTGTTACTGCTGCTGGAGTTGTTCTAACGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACTCATTACAGTTGGCGGTTTTCTGGGGTTTGTATTGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACAGTCCCTCGTCTGACAACTTATCTAAATTTTTCGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACTTGGCTAAATCACCATCATCCACAGAGGCGATCGGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACCAGACTTCTGGCTATTTATCAGTCTGATATCATTGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACATAGAAAATCAAATCATATATGATTGATATTCCTTTATTGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACGTGGTAGGAATGGCCCCAAGAACCACACATTAAGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACAAGAAGATTTCGATAATGACGGGATTCCTGACTCTAGTGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACAGATTACATCATAAAGCGTAGGTGTTATGTATTTGTGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACCTGTCCTTCAGAAGATACGGGAATACGTTAGGGAGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACTTGTCAAGTATGGCTTTGAATCCATTCTCTAATCTGGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACCTATACGTGCTGCAAGTGCTGTATGTGTAGTATCAGATACTGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACCTATCTAGATAAACTTATTCTATCTCTATGGGAGTTTACAAGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACTCGATATCCAAATGCACGAATAAGACCACCTAACAGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACTTTTCTATGAGTTGCACGGTAAGCAGAACGACGAAGAGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACTTATCATTTAAAGCTTTTTGAATTGGTGACAAGTCCGGGATGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACCCTGAGGAAGTACAGCTAGAGGAACGCGCAGAATATGGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACATCAAAATGCTTATTTGCCTCTACAATCTTTTGGCGTGGGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACATCAAGTTTACAGCTTGTACAACGGGGCTGCTTCTGGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACAAAGCCTTTGTTTTTCAAAATCAGTATTAGAAAATTTATTTGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACTGGAAGTCTAGAAGGAAAAGTGAATATTTTAGAAAGGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAACCTGATAGCTAATTCACTAGCACCATTAGCTATCTCAAGTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC

>NC_019771|19|9|5001036-5003639|PILER-CR
GTTTCAATTCCTATTAGGGATTATTTGAAATTTCAAC	CCTTGATCAGTTTGAAAAGCTATTGCATCACCTTCT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	GAGCCTAGGAAGCTCCCTAGCGTTGCGCTGCTGCC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TTTGTATGCAATTGGAATTACGTGGGACGCAGA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CACTACTCCAAGTGAAAAACGGTTGATAGAGGCAGCGA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CATTGTCCGACAGCATCATAGCTTTATTGAAAGCGTGATT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TGAGACATGGTTTGTGAGAGAACTGGAATTAAAT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	ATCAAAGAAGAAAACGGTAATGCAATCTTAATTGTC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TCATTAAAATTAGCTTGTCGTATTGACGATAACGACAAC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	GCTCTCTACTCTTACGCACTAGATAAGTCTCCAAT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AAAAGGTAGTTCGTTTGTATCAGTAAATCGTGAT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TATGGTATTAATCAATTATCGCTTGGGGAAAATCG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AATCTCTCAAAATCTGAACCATTAATATATTATTGT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CTGACCTTATCCCCACCAGTCAAGCTGAGGAAAC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	GTTCGGTCTGTTACTGCTGCTGGAGTTGTTCTAAC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TCATTACAGTTGGCGGTTTTCTGGGGTTTGTATT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AGTCCCTCGTCTGACAACTTATCTAAATTTTTC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TTGGCTAAATCACCATCATCCACAGAGGCGATCG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CAGACTTCTGGCTATTTATCAGTCTGATATCATT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	ATAGAAAATCAAATCATATATGATTGATATTCCTTTATT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	GTGGTAGGAATGGCCCCAAGAACCACACATTAA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AAGAAGATTTCGATAATGACGGGATTCCTGACTCTAGT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AGATTACATCATAAAGCGTAGGTGTTATGTATTTGT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CTGTCCTTCAGAAGATACGGGAATACGTTAGGGA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TTGTCAAGTATGGCTTTGAATCCATTCTCTAATCTG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CTATACGTGCTGCAAGTGCTGTATGTGTAGTATCAGATACT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CTATCTAGATAAACTTATTCTATCTCTATGGGAGTTTACAA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TCGATATCCAAATGCACGAATAAGACCACCTAACA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TTTTCTATGAGTTGCACGGTAAGCAGAACGACGAAGA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TTATCATTTAAAGCTTTTTGAATTGGTGACAAGTCCGGGAT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CCTGAGGAAGTACAGCTAGAGGAACGCGCAGAATATG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	ATCAAAATGCTTATTTGCCTCTACAATCTTTTGGCGTGG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	ATCAAGTTTACAGCTTGTACAACGGGGCTGCTTCTG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AAAGCCTTTGTTTTTCAAAATCAGTATTAGAAAATTTATTT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TGGAAGTCTAGAAGGAAAAGTGAATATTTTAGAAAG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CTGATAGCTAATTCACTAGCACCATTAGCTATCTCAA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC

>NC_019771|19|19|5001036-5003639|CRISPRCasFinder
GTTTCAATTCCTATTAGGGATTATTTGAAATTTCAAC	CCTTGATCAGTTTGAAAAGCTATTGCATCACCTTCT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	GAGCCTAGGAAGCTCCCTAGCGTTGCGCTGCTGCC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TTTGTATGCAATTGGAATTACGTGGGACGCAGA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CACTACTCCAAGTGAAAAACGGTTGATAGAGGCAGCGA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CATTGTCCGACAGCATCATAGCTTTATTGAAAGCGTGATT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TGAGACATGGTTTGTGAGAGAACTGGAATTAAAT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	ATCAAAGAAGAAAACGGTAATGCAATCTTAATTGTC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TCATTAAAATTAGCTTGTCGTATTGACGATAACGACAAC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	GCTCTCTACTCTTACGCACTAGATAAGTCTCCAAT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AAAAGGTAGTTCGTTTGTATCAGTAAATCGTGAT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TATGGTATTAATCAATTATCGCTTGGGGAAAATCG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AATCTCTCAAAATCTGAACCATTAATATATTATTGT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CTGACCTTATCCCCACCAGTCAAGCTGAGGAAAC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	GTTCGGTCTGTTACTGCTGCTGGAGTTGTTCTAAC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TCATTACAGTTGGCGGTTTTCTGGGGTTTGTATT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AGTCCCTCGTCTGACAACTTATCTAAATTTTTC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TTGGCTAAATCACCATCATCCACAGAGGCGATCG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CAGACTTCTGGCTATTTATCAGTCTGATATCATT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	ATAGAAAATCAAATCATATATGATTGATATTCCTTTATT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	GTGGTAGGAATGGCCCCAAGAACCACACATTAA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AAGAAGATTTCGATAATGACGGGATTCCTGACTCTAGT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AGATTACATCATAAAGCGTAGGTGTTATGTATTTGT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CTGTCCTTCAGAAGATACGGGAATACGTTAGGGA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TTGTCAAGTATGGCTTTGAATCCATTCTCTAATCTG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CTATACGTGCTGCAAGTGCTGTATGTGTAGTATCAGATACT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CTATCTAGATAAACTTATTCTATCTCTATGGGAGTTTACAA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TCGATATCCAAATGCACGAATAAGACCACCTAACA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TTTTCTATGAGTTGCACGGTAAGCAGAACGACGAAGA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TTATCATTTAAAGCTTTTTGAATTGGTGACAAGTCCGGGAT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CCTGAGGAAGTACAGCTAGAGGAACGCGCAGAATATG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	ATCAAAATGCTTATTTGCCTCTACAATCTTTTGGCGTGG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	ATCAAGTTTACAGCTTGTACAACGGGGCTGCTTCTG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AAAGCCTTTGTTTTTCAAAATCAGTATTAGAAAATTTATTT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TGGAAGTCTAGAAGGAAAAGTGAATATTTTAGAAAG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CTGATAGCTAATTCACTAGCACCATTAGCTATCTCAA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC

>NC_019771|19|6|5001036-5003639|CRT
GTTTCAATTCCTATTAGGGATTATTTGAAATTTCAAC	CCTTGATCAGTTTGAAAAGCTATTGCATCACCTTCT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	GAGCCTAGGAAGCTCCCTAGCGTTGCGCTGCTGCC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TTTGTATGCAATTGGAATTACGTGGGACGCAGA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CACTACTCCAAGTGAAAAACGGTTGATAGAGGCAGCGA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CATTGTCCGACAGCATCATAGCTTTATTGAAAGCGTGATT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TGAGACATGGTTTGTGAGAGAACTGGAATTAAAT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	ATCAAAGAAGAAAACGGTAATGCAATCTTAATTGTC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TCATTAAAATTAGCTTGTCGTATTGACGATAACGACAAC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	GCTCTCTACTCTTACGCACTAGATAAGTCTCCAAT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AAAAGGTAGTTCGTTTGTATCAGTAAATCGTGAT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TATGGTATTAATCAATTATCGCTTGGGGAAAATCG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AATCTCTCAAAATCTGAACCATTAATATATTATTGT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CTGACCTTATCCCCACCAGTCAAGCTGAGGAAAC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	GTTCGGTCTGTTACTGCTGCTGGAGTTGTTCTAAC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TCATTACAGTTGGCGGTTTTCTGGGGTTTGTATT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AGTCCCTCGTCTGACAACTTATCTAAATTTTTC
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TTGGCTAAATCACCATCATCCACAGAGGCGATCG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CAGACTTCTGGCTATTTATCAGTCTGATATCATT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	ATAGAAAATCAAATCATATATGATTGATATTCCTTTATT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	GTGGTAGGAATGGCCCCAAGAACCACACATTAA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AAGAAGATTTCGATAATGACGGGATTCCTGACTCTAGT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AGATTACATCATAAAGCGTAGGTGTTATGTATTTGT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CTGTCCTTCAGAAGATACGGGAATACGTTAGGGA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TTGTCAAGTATGGCTTTGAATCCATTCTCTAATCTG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CTATACGTGCTGCAAGTGCTGTATGTGTAGTATCAGATACT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CTATCTAGATAAACTTATTCTATCTCTATGGGAGTTTACAA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TCGATATCCAAATGCACGAATAAGACCACCTAACA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TTTTCTATGAGTTGCACGGTAAGCAGAACGACGAAGA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TTATCATTTAAAGCTTTTTGAATTGGTGACAAGTCCGGGAT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CCTGAGGAAGTACAGCTAGAGGAACGCGCAGAATATG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	ATCAAAATGCTTATTTGCCTCTACAATCTTTTGGCGTGG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	ATCAAGTTTACAGCTTGTACAACGGGGCTGCTTCTG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	AAAGCCTTTGTTTTTCAAAATCAGTATTAGAAAATTTATTT
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	TGGAAGTCTAGAAGGAAAAGTGAATATTTTAGAAAG
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC	CTGATAGCTAATTCACTAGCACCATTAGCTATCTCAA
GTTTCAATCCCTAATAGGGATTATTTGAAATTTCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_171815811.1\|5009203_5010478_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379742
NC_019771.1\|WP_015216392.1\|4997790_4998690_+\|2-carboxy-1,4-naphthoquinone-phytyltransferase	unknown	unknown	gnl\|CDD\|236015
NC_019771.1\|WP_015216404.1\|5013315_5013864_+\|pentapeptide-repeat-containing-protein	unknown	unknown	gnl\|CDD\|224276
NC_019771.1\|WP_015216399.1\|5007750_5009079_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|377544
NC_019771.1\|WP_015216387.1\|4991327_4992881_-\|sodium:proton-antiporter	unknown	unknown	gnl\|CDD\|223104
NC_019771.1\|WP_015216397.1\|5005664_5006903_-\|aminoglycoside-phosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|366736
NC_019771.1\|WP_015216398.1\|5007358_5007673_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227835
NC_019771.1\|WP_015216395.1\|5003911_5004361_-\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|223894
NC_019771.1\|WP_015216384.1\|4987730_4989728_-\|M48-family-metalloprotease	unknown	unknown	gnl\|CDD\|320697
NC_019771.1\|WP_015216401.1\|5010505_5011831_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|378508
NC_019771.1\|WP_015216396.1\|5004517_5005609_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375425
NC_019771.1\|WP_015216386.1\|4990791_4991331_+\|DUF3124-domain-containing-protein	unknown	unknown	gnl\|CDD\|378638
NC_019771.1\|WP_015216391.1\|4995851_4997261_-\|isochorismate-synthase	unknown	unknown	gnl\|CDD\|224091
NC_019771.1\|WP_015216393.1\|4998689_4999649_+\|o-succinylbenzoate-synthase	unknown	unknown	gnl\|CDD\|235061
NC_019771.1\|WP_015216405.1\|5014017_5014374_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015216402.1\|5012005_5012623_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015216385.1\|4989913_4990597_+\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643
NC_019771.1\|WP_015216390.1\|4994938_4995610_-\|glutathione-S-transferase	unknown	unknown	gnl\|CDD\|198298
NC_019771.1\|WP_015216389.1\|4993122_4994430_+\|glutamate-5-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|234685
NC_019771.1\|WP_015216394.1\|4999633_5001001_+\|2-succinylbenzoate--CoA-ligase	unknown	unknown	gnl\|CDD\|236019

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_171815811.1\|5009203_5010478_+\|hypothetical-protein	gnl\|CDD\|379742	pfam15615, TerB_C, TerB-C domain. TerB-C occurs C-terminal of TerB in TerB-N containing proteins. This domain displays multiple conserved acidic residues (TerBC). The presence of conserved acidic residues in both TerB-N and TerB-C suggests that they, like the TerB domain, might also chelate metals. These two domains may also occur together in the same protein independently of TerB.	6.8777e-15
NC_019771.1\|WP_015216392.1\|4997790_4998690_+\|2-carboxy-1,4-naphthoquinone-phytyltransferase	gnl\|CDD\|236015	PRK07419, PRK07419, 2-carboxy-1,4-naphthoquinone phytyltransferase.	0
NC_019771.1\|WP_015216404.1\|5013315_5013864_+\|pentapeptide-repeat-containing-protein	gnl\|CDD\|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	6.7146e-30
NC_019771.1\|WP_015216399.1\|5007750_5009079_+\|ATP-binding-protein	gnl\|CDD\|377544	pfam05673, DUF815, Protein of unknown function (DUF815). This family consists of several bacterial proteins of unknown function.	1.30911e-141
NC_019771.1\|WP_015216387.1\|4991327_4992881_-\|sodium:proton-antiporter	gnl\|CDD\|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	9.79461e-81
NC_019771.1\|WP_015216397.1\|5005664_5006903_-\|aminoglycoside-phosphotransferase-family-protein	gnl\|CDD\|366736	pfam01636, APH, Phosphotransferase enzyme family. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include: aminoglycoside 3'-phosphotransferase or kanamycin kinase / neomycin-kanamycin phosphotransferase and streptomycin 3''-kinase or streptomycin 3''-phosphotransferase. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. This family also includes homoserine kinase. This family is related to fructosamine kinase pfam03881.	1.29679e-10
NC_019771.1\|WP_015216398.1\|5007358_5007673_-\|hypothetical-protein	gnl\|CDD\|227835	COG5548, COG5548, Small integral membrane protein [Function unknown].	1.06356e-22
NC_019771.1\|WP_015216395.1\|5003911_5004361_-\|acyl-CoA-thioesterase	gnl\|CDD\|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	1.10064e-31
NC_019771.1\|WP_015216384.1\|4987730_4989728_-\|M48-family-metalloprotease	gnl\|CDD\|320697	cd07338, M48B_HtpX_like, Peptidase M48 subfamily B HtpX-like membrane-bound metallopeptidase. This HtpX family of peptidase M48 subfamily B includes uncharacterized HtpX homologs and consists of proteins smaller than Ste24p, with homology restricted to the C-terminal half of Ste24p. HtpX expression is controlled by the Cpx stress response system, which senses abnormal membrane proteins. HtpX participates in the proteolytic quality control of these misfolded proteins by undergoing self-degradation and collaborating with FtsH, a membrane-bound and ATP-dependent protease, to eliminate them. HtpX, a zinc metalloprotease with an active site motif HEXXH, has an FtsH-like topology, and is capable of introducing endoproteolytic cleavages into SecY (also an FtsH substrate). However, HtpX does not have an ATPase activity and will only act against cytoplasmic regions of a target membrane protein. Thus, HtpX and FtsH have overlapping and/or complementary functions, which are especially important at high temperature; in E. coli and Xylella fastidiosa, HtpX is heat-inducible, while in Streptococcus gordonii it is not.	1.2916e-66
NC_019771.1\|WP_015216401.1\|5010505_5011831_+\|ATP-binding-protein	gnl\|CDD\|378508	pfam10923, DUF2791, P-loop Domain of unknown function (DUF2791). This is a family of proteins found in archaea and bacteria. This domain contains a P-loop motif suggesting it binds to a nucleotide such as ATP.	0
NC_019771.1\|WP_015216396.1\|5004517_5005609_-\|hypothetical-protein	gnl\|CDD\|375425	pfam17914, HopA1, HopA1 effector protein family. This family includes the HopA1 effector protein from Pseudomonas syringae. Structurally this protein has an alpha + beta fold. The effector protein HopA1 was shown to affect the EDS1 complex by binding EDS1 directly and activating the immune response signaling pathway.	5.98817e-72
NC_019771.1\|WP_015216386.1\|4990791_4991331_+\|DUF3124-domain-containing-protein	gnl\|CDD\|378638	pfam11322, DUF3124, Protein of unknown function (DUF3124). This bacterial family of proteins has no known function.	7.74925e-77
NC_019771.1\|WP_015216391.1\|4995851_4997261_-\|isochorismate-synthase	gnl\|CDD\|224091	COG1169, MenF, Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.78289e-135
NC_019771.1\|WP_015216393.1\|4998689_4999649_+\|o-succinylbenzoate-synthase	gnl\|CDD\|235061	PRK02714, PRK02714, o-succinylbenzoate synthase.	0
NC_019771.1\|WP_015216385.1\|4989913_4990597_+\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	2.96713e-57
NC_019771.1\|WP_015216390.1\|4994938_4995610_-\|glutathione-S-transferase	gnl\|CDD\|198298	cd03189, GST_C_GTT1_like, C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases. Glutathione S-transferase (GST) C-terminal domain family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. GSTs also show GSH peroxidase activity and are involved in the synthesis of prostaglandins and leukotrienes. The GST fold contains an N-terminal thioredoxin-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. GSH binds to the N-terminal domain while the hydrophobic substrate occupies a pocket in the C-terminal domain. GTT1, a homodimer, exhibits GST activity with standard substrates and associates with the endoplasmic reticulum. Its expression is induced after diauxic shift and remains high throughout the stationary phase. S. pombe GST-III is implicated in the detoxification of various metals.	2.82793e-51
NC_019771.1\|WP_015216389.1\|4993122_4994430_+\|glutamate-5-semialdehyde-dehydrogenase	gnl\|CDD\|234685	PRK00197, proA, gamma-glutamyl phosphate reductase; Provisional.	0
NC_019771.1\|WP_015216394.1\|4999633_5001001_+\|2-succinylbenzoate--CoA-ligase	gnl\|CDD\|236019	PRK07445, PRK07445, O-succinylbenzoic acid--CoA ligase; Reviewed.	0

>NC_019771.1|WP_015216394.1|4999633_5001001_+|2-succinylbenzoate--CoA-ligase
MEQPLEYLQKIKNHDWLIGYDSQDFQQIATELYSELTQLSTKSTPPKIILAEREPVRFLASFIAACAAKCPVFLCNPDWGKNEWEQVIDLVKPDIVWGLDNINLQPPIINHQSPITNAIMIPTGGSSGKIKFAIHTWETLTASVQGFTEYFQLKTVNSFCVLPLYHVSGLMQFMRSFTTGGKLVITPFKEVEFSQIPNINPAEFFISLVPTQLQRLLQNPQLTQWLTQYHTVLLGGAPAWGELLEKAKFHHIRLAPTYGMTETASQIATLKPDEFLNGKTNSGKILPHAKITISNQTGNINIQAKSLALGYYPELWKNTDNFAVDDIGFLDSQGYLHIIGRSSDKIITGGENIYPAEIESAIRKTNMVIDVCVIGIPDKHWGQVLTAIYIPKNPNTSILEIQTQLKNQLGKFKIPKHWISLPNLPRNGQGKINCQQLQKIAEDFLANNNLALPSL
>NC_019771.1|WP_015216393.1|4998689_4999649_+|o-succinylbenzoate-synthase
MNYQFSFRPIRQKFTRPIVTSHGIWEIRESMIIRLIDVKGTVSWGEISPISWFGSETIKQALDFCSQLPTEITREIIFSIPNNLPACQFGFESALEKLEKNNELTSIDNLTYSGLLPAGKAALDQWQGLWKQGYKTFKWKIGVDKIATELNVFNSLIQNLPNSLKLRLDANGGLSYEEAKLWLKTCENLQTKIEFIEQPLPINQFREMLELSNLYSTQIALDESVATLQQLEDCYKQSWRSIYVIKPGIIGSPSQLRKFCQEYEIDLVFSSVLETEIGRQAALQLAAELSKNNRAVGFGINHFFTQQPENWLQSLWNNL
>NC_019771.1|WP_015216392.1|4997790_4998690_+|2-carboxy-1,4-naphthoquinone-phytyltransferase
MTQNQISIPKNKLWLAAIKPPMYSVAIMPIWVGSAVAFAETKVFNGVIFAVFMTAAILILAWENISNDVFDAETGIDQNKHHSLVNLTGDKQLMFWLGNLCLGSGLLGIIAIALLQQDPAVIAIILLCCALGYMYQGPPFRLGYQGLGEILCFFAFGPLGMTAAYYSQTQTWSITNLAASVIVGIVTSLVLFCSHFHQVKDDIAAGKKSPIVRLGTETGAKVLVWFTASIYPFTMLFVILNIFPIWTLLSFLSLPYAYKLCRHVLENHNQPDKVNNCKFIAVKVHFLSCLFLGIGFVIG
>NC_019771.1|WP_015216391.1|4995851_4997261_-|isochorismate-synthase
MTISPCRSRFFVDYKDLHQLLLAVQEKCCENHTQQIVSISLEIDLIDPLIVLDKFAQANTLNFYFENKSKGEAITAIDSITKLKISGADRFNQAEDFIKNCRKNIISFGNIFQGFAGSHFFCSFSFFDQHNQVNYPFPSATIFLPKLQVAVKNESCVLVMNSVINADINIQTILQELKTKIQSLQSLTKPNIEIIPAKFIKENIINSDNFKYSVLSALEKIKSNHLIKIVLADALDVKSYRPFNLFKSLNNLRQLHPNCYVFSTSNGKGQNFIGASPERLISIQNQQLITDALAGSAPRGKTPREDAENANRLINSTKEKHEHKLVLDFITQRLSQLGLFPQILSPRLRQLSNIQHLWTPISAVVPANVHPLKIVGQLHPTPAVAGAARDVACAEIRNYESFERGLYAAPLGWVDSSGNCEFIVGIRSALIDGDRARLYAGAGIVAGSDPDKEFAEVQLKLQALLKALV
>NC_019771.1|WP_015216390.1|4994938_4995610_-|glutathione-S-transferase
MIVVHHLNNSRSQRVLWLLEELELPYEIKCYKRDPQTMLAPASLREVHPLGKSPVITDGELTLAESGAIIEYLIERYGNGRLLPASGTPEHLRYTYWLHYAEGSAMPPLVLKLIFDEIEKSSMPFFARPIARSIANRVKSSFIEPYITQNLDYMEMELGKSTWFAGNEFTAADIQISFPLEAAVARAGLNASRPKLMAFLNRIHTRPAYQQALERGGAYELAS
>NC_019771.1|WP_015216389.1|4993122_4994430_+|glutamate-5-semialdehyde-dehydrogenase
MTTVQNALPLIQIAQETRQAASKLGLLSTEDKNQAIDAIALALESAREEILSANVADCQAAVAEGIAKPLYKRLQLDEHKLRDAIAGVRDVGKLEDPVGKVQIHREIDSGLILKRITCPLGVLGIIFEARPEAAIQIVSLAIKSGNGVILKGGKEALRSCAAIVKAIKQGLSHTAVNPDAVQLLTTREEILELLKLDKYVDLIIPRGSNSFVRFVQENTRIPVLGHADGICHLYVDQAADINKAINITVDSKTQYPAACNAIETLLVHSSIASEFLPQVAADLEAHNVELRGDERTLKILPNISIATTTDWETEYSDLILSIKIVDSLEDAITHIDNYGSRHTEAIITEDIKAAETFQALVNAAGVYHNCSTRFADGFRYGFGAEVGISTQQMPPRGPVGLEGLITYKYKMSGDGHIVDSYTGANAKSFTHRDLE
>NC_019771.1|WP_015216387.1|4991327_4992881_-|sodium:proton-antiporter
MNITELVKISIILLLVATGVALVSRRLRIPYVTGLVLAGLPITELLSRPIGLDPALVLNLFLPILIFDAGINTDISRLRSTFKPIALLAGPGAVLSSAIIAVLLKFGLGLTWIPALFVGVILANTDTVSMIAVFKEIQVPSRLSAIVEGETLFNDAAALVSFNLILQVYSTGSLTLLEGIQQVLFISVGGCLVGLVLGYLSIPIFSRLDDPLGSLLLTVAVALGTFQVGQSLGVSGAVAVVVAGLIFGNFGLSRNTSASSRITLFSFWEYASFTVNTFIFLLIGVEINLVTLWKTLPAILLAVLVYQAGRILTVYPLLTAIRWFDRPIPLRWQHLLFLGNIKGSLSMALVLSLPSTLPGREFLITLVFGCVLVSLVGQGLSLPGLVKRLKLSKFSEAQHQVEEMQAQLMTGKAAQDELDSLLKSGVLPKSLYEEMRSAYQVRIAGAEKALREFYNRRPDELGAKRDDSSKLETIRRRLLLAEKGALNEAIRKRILAEDIARGRIQTIDEQLLQLDDD
>NC_019771.1|WP_015216386.1|4990791_4991331_+|DUF3124-domain-containing-protein
MKFYLHIYLVVVVILLASCKATEISSKSQPHTTQAISSQKIVTLDKNFKIAMGQTIYVPVYSHIYHHNRQEIFNLAATLSIRNTDLANPLIITSVRYYDSDGKLVKNYLEQPIQLDALASTDFFINRNNTSGGLGANFIVEWVASTEISEPIVEAIMIGTDFQQGISFTSSGKVIKSQN
>NC_019771.1|WP_015216385.1|4989913_4990597_+|TrkA-family-potassium-uptake-protein
MYVLIGGAGLVGLSLAQKLVELGHTVAIIDIDSTACRYAREQVGAMAFEGSAVSTEVLLEAGIRKANSLAAVLRSDALNLALVTLAKHYGVPHILSRMRHPDFAEPLRIVGANHIISTVELAVSTMVNAIEYPQVESMMHFDQGQIEVLKLSIPTNCYVVNRSVAEIAQDSRFPTGSLIIGYQPHPQEDLMIPNGSTVLEPGSTILIVTKPGCVHQVIDFIEGCENR
>NC_019771.1|WP_015216384.1|4987730_4989728_-|M48-family-metalloprotease
MSLQSGLDAFQQGQYQEAVYLLEEFSQNSLELNSPDYLTAQMWLMKAYQKTGDTEQATILWQKLINSDNPQVREWAEQDRPFFSSVTQPSFQKAGRAAAVGVNLAMKGVGGSLALASGITIALLFGMVFVLGLSLVLIASSSDPVTGLAIAIAITLIFNLAAFFFSPFLMDLSQNWLYKTRWVNLAEIENLSPETGKIIRQVCQQKNITTPRLGIIDDQNPTAFTYGSLPNSARLVVSQGLFTYLDDDEVATVYAHELGHIVHWDFAVMTVASTLVQICYLVYSTARRFTRGGGDNKIKDALETAGFVAYIFYIIGTYLLLYLSRTREYFADHFAAETTGNPNGLSRALVKIAYGIVEEGSRAQEPSRLIEGTRALGIYDHKAATTTGTAYRISSDPQKIGRIFLWDMFNPWGWWMELNSTHPLTGKRVRALSTYAEQLGLPTEFDMGKVMGEGQTLNKKKLYGNFFLDVVLYGAEAIGLFLGLFIGVLLWSVSTTSNPGLMLGAPFIGLGIGILIKAFVMFPDYMKAPATDILTLMSDPYASPLRGQPAKLQGELIGRGDSGYKFGSDLKLQDPSGMLYLHYASRFGPIGNFLFGMKRVETLIGQQVGTIGWFRRGVMPWMDLIQLEGENGTIVNSYHRFWSFILSGGSIILGVVLIGFLNGKP
>NC_019771.1|WP_015216395.1|5003911_5004361_-|acyl-CoA-thioesterase
MIFTYQRTIRFQDTDAAGVVYFANTLSICHEAYEESLGSCGINIKTFFTNPAVAFPIVHANVDFLRPMYCGDKLMISLIPQKIGMDKFEITYEITVDEVIVAKAITRHVCIHASSRIKQELPNEMISWLETNRRDAEGAERRKSREEII
>NC_019771.1|WP_015216396.1|5004517_5005609_-|hypothetical-protein
MLDNSTNQILNSLFDIATNIQIEPNFCIQHPHYQPFALPATVANRFQQNSQDLQHKYLSLLLRNFLHGIYYNGSLQTVLAVNSDHENYSPQKTLEPSSSLGIDWDFYEQLHENNHGHGHYDPNWEVLRLEPDGSMAVTKNGLTLYVEPECYLQSSKKSVKPGELIAIWMPKNRLQNGCYVAVSNLGQERQDTPKTDVEVGRIYFNFTPSGAIALMDSLTQQLNTANIPFSFEVLYNPSAYGRYDAGILHFQRQDYPAIHKILQPVYKQHQCYFQPEIPLFTKFLAPGLSLAEEPSQKFAAQESFGMNRCQIVANALLEAWDKGKNAIEERMRIIDQHFAQHLIDVQRPYLNPSSEDIYIPLNC
>NC_019771.1|WP_015216397.1|5005664_5006903_-|aminoglycoside-phosphotransferase-family-protein
MILSLSSQNVIQYLQNAGLCSSGDGILYESELPESGRNNRNLLVSLVDDRKLLVKQENRQNCGSSPHDFFNEWLFHQLLQQFPVLGNIAAISSSLLHFDEDNSILVRSYLSEYMELGKFYKNNSTFTTEIATAIGNTLASLHSSTCQRREYRDFMDTAPQGQFRYNFYNPAQGIGSINQDVFGNIPTEALKFHTLYQRYESLESAIADLSYEWKPCCLTHNDLQLNNILIHSRWQQLDNCLIKFIDWEACAWGDPAFDLGTLLASYVNIWLSSLVVDPSLELEESLNLAMIPLEVIQPSISALLRAYLHAFPMILEYRRDFVIRVIQFTGLALTHQIQNIILCHKYFDNTHLCMLEVAKSLLTMPEQAMLTIFGSSETEILQSVSGLNNIAKPEKEKQLLRIYYEKTRLRGC
>NC_019771.1|WP_015216398.1|5007358_5007673_-|hypothetical-protein
MNLSILATFGYGVLALVGGIIGYIQVKSKISLLSGSISGLLLIFAGYYQLQGQTWGLTLATLVTAILVVLFAFRFAKTRKFMPAGLMIIFGMLALAVMVRQIFG
>NC_019771.1|WP_015216399.1|5007750_5009079_+|ATP-binding-protein
MSTPNTSSYTQVQFLQRQAASLLLYQSVLKGEVAIAFLDLLQAIRYTDADGRDCLQAYGNYFQALAASKQTWEEYLISQILIADNPFTRLAQQRDFTDLPPALVAAARHDLQVLQNLHECNSAILSEWVQVVAHLPVSPVVWYQEAEKVKIDTDLVTSIPQLEIWADAVEDLAAYYQQHGTGLFAEYRAFSWQNGYFVAIPYPDPVQLNTLVGYEWQKDTLLKNTKFLLSGQPALHVLLYGSRGSGKSSLVKSLLNECNHHNLRLIEVAKSELQDLPKIVEQLRGVPQKFIIFVDDLSFEEDDDAFKSLKVVLEGSLTARPQNIVVYATSNRRHLIREYFSDRPTPKDNEEVHAWDTMQEKLSFSDRFGITLTFEPADQKTYLNIVNHLAAQVGINLNQEDLEYKALQWATRHNGRSGRTAQQFIDFLKSDLALFNGNNNRL
>NC_019771.1|WP_171815811.1|5009203_5010478_+|hypothetical-protein
MHSAIISNRLILGISAFSVSFGLSLVPNWDFNKAFFTALITVLATYSAALFVDKRRRNYEMLILSSLHKRIRELEGLKYRIVREIKQIDEHRNILYTESQHLQNQIAESRNQRDIIHRELGSYAGQKKQLESEINTLQNEIHYLKSSAEELDQTCSHLTAEKRRLELNSNVSRSELTQLQSQIEAFKQEKQEIESNLTLVNRLKPQLEEKLYELRTEIQELEIKISQRNNLLIDTTTAREIVANNLANLQIQTQTQQAEINQLQNQIALLQDERDLLQNQVWELLQNMETLNPETLSENIQENEIELFPFDELLETIDSQPQTSNLPPEWSHFLENLPTYEIQVLKAIVEEDNPKAIIKQIAEEHITMPNLLIDSINEIANNTLGELIIETGEEIPEIYQEHLLNVKKMIAIYEQLITKSISPN
>NC_019771.1|WP_015216401.1|5010505_5011831_+|ATP-binding-protein
MTKLKISKKISTALINSLGAGVVPRVGIEHIAVGREKELNSLLQNLNDIGEGVAAFRFIIGNYGAGKSFMLQMIRNRAMEQGFVVADADLSSERRLAGSHNEGLATYRELMSRLATKTRPDGGALVSILEGWINKIQQEVAKETGTRPNDEGFDEQVETKIREVVHYIEDLVHGFDFGSVIIAYWRSYRLDDDDLKNASLRWLRGEFNTKTEAKAALGVRVIIDDDTWFDYIKLLAKFVAEIGYKGLFILVDEAVNLYQISTTVTREKNYNRLLAMFNDTMQCKAENLGIVIGGTTKFLEDPNRGLFADQAWRRRTKESRFVTQANVQEYLGPVIRLNPLTETEILTLLQRLTEIHALNFGYEENLTNRELKEFIQEIITRLGAEALLTPGEIIRDFISVLNVLYQNPEIKFTELIHGANFKPTAAGKDANLGEDAAEFSL
>NC_019771.1|WP_015216402.1|5012005_5012623_-|hypothetical-protein
MTADLTSSITSDFTSILFQTAAAYRKGNKPPMAEVVVNALLQAEKAAKQERLNYTFDSLIGKWRLCFATGTKKIRKRGGIILGKGFYVPKLVKIHLAFSNTQEQVLGRGEIYNQVQLGSILLKLTGPSQYLGKKNLLAFDFTQMKISLFNHLLYNQPIRSGKDQLDDFYNQSIAKLPFFAFFLVTADFIAARGRGGGLAIWIREH
>NC_019771.1|WP_015216404.1|5013315_5013864_+|pentapeptide-repeat-containing-protein
MDTISFLRQYTSGERNFNRVSLHQAKLTKANLSGVNLSEADLSGADLSEANLSKCNLTRANLTNADLSRANLQGANLSEVNLIGADLTKVNFKETNLSGADLRGANLKLANLLGANLTESEISGADFSGANLQNANLIGSNINEAEFNGANLANVMITELEITGEVLHIGLSHKWITWAGSY
>NC_019771.1|WP_015216405.1|5014017_5014374_-|hypothetical-protein
MNKFILTLFSSPVLISSLLTMGVMLNQAQAGEPKAKNTDNLSCIRNKHKVGLVCARVSVLAQVPEYQAQPEDASTPDDVLLLEFNVEESNKAIDLFGCDCPACINSLRQMRGVTPLVY

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Crispr_ID: NC_019771_20

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_20

5516088-5516212

Unclear

A:N

Consensus_repeat	Method
GTTAAAGAAGCCTAACGCACCCTACAAATTTGATATTTTTTAAATTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019771_20

>merge|NC_019771|20|5516088-5516212|CRISPRCasFinder
GTTAAAGAAGCCTAACGCACCCTACAAATTTGATATTTTTTAAATTGGAAGTTCTCTGTTTCTGTGATTATTGGTGTGTTAAAGAAGCCTAACGCACCCTACAAATTCGATATTTTTTAAATTGG

>NC_019771|20|20|5516088-5516212|CRISPRCasFinder
GTTAAAGAAGCCTAACGCACCCTACAAATTTGATATTTTTTAAATTGG	AAGTTCTCTGTTTCTGTGATTATTGGTGT
GTTAAAGAAGCCTAACGCACCCTACAAATTCGATATTTTTTAAATTGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_042466168.1\|5519892_5520321_+\|photosystem-II-complex-extrinsic-protein-PsbU	unknown	unknown	gnl\|CDD\|235048
NC_019771.1\|WP_150111048.1\|5513137_5516017_-\|family-10-glycosylhydrolase	unknown	unknown	gnl\|CDD\|224563
NC_019771.1\|WP_015216835.1\|5520452_5522120_+\|L-aspartate-oxidase	unknown	unknown	gnl\|CDD\|236010
NC_019771.1\|WP_015216823.1\|5503333_5503486_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_171815815.1\|5522176_5522347_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015216826.1\|5505201_5505882_-\|uracil-DNA-glycosylase	unknown	unknown	gnl\|CDD\|235376
NC_019771.1\|WP_015216839.1\|5526419_5527268_-\|BtpA/SgcQ-family-protein	unknown	unknown	gnl\|CDD\|223511
NC_019771.1\|WP_015216829.1\|5507704_5512549_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|223715
NC_019771.1\|WP_015216821.1\|5501577_5502870_+\|AmpG-family-muropeptide-MFS-transporter	unknown	unknown	gnl\|CDD\|341039
NC_019771.1\|WP_015216822.1\|5502854_5503256_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015216831.1\|5516225_5517551_-\|TIGR03279-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|132322
NC_019771.1\|WP_015216828.1\|5506484_5507696_-\|EAL-domain-containing-response-regulator	unknown	unknown	gnl\|CDD\|238923
NC_019771.1\|WP_015216838.1\|5525369_5526359_-\|vitamin-K-epoxide-reductase-family-protein	unknown	unknown	gnl\|CDD\|240599
NC_019771.1\|WP_015216840.1\|5528059_5529379_+\|30S-ribosomal-protein-S12-methylthiotransferase-RimO	unknown	unknown	gnl\|CDD\|273453
NC_019771.1\|WP_015216833.1\|5518748_5519516_+\|DUF3120-domain-containing-protein	unknown	unknown	gnl\|CDD\|371465
NC_019771.1\|WP_042465395.1\|5503595_5504045_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_019771.1\|WP_015216827.1\|5505878_5506268_-\|phosphomannose-isomerase-type-II-C-terminal-cupin-domain	unknown	unknown	gnl\|CDD\|380343
NC_019771.1\|WP_015216837.1\|5522865_5525094_-\|CHASE2-domain-containing-protein	unknown	unknown	gnl\|CDD\|226703
NC_019771.1\|WP_015216825.1\|5504140_5504899_+\|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|224331
NC_019771.1\|WP_015216832.1\|5517625_5518561_-\|undecaprenyl-diphosphate-phosphatase	unknown	unknown	gnl\|CDD\|376891

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_042466168.1\|5519892_5520321_+\|photosystem-II-complex-extrinsic-protein-PsbU	gnl\|CDD\|235048	PRK02515, psbU, photosystem II complex extrinsic protein PsbU.	1.36464e-71
NC_019771.1\|WP_150111048.1\|5513137_5516017_-\|family-10-glycosylhydrolase	gnl\|CDD\|224563	COG1649, COG1649, Uncharacterized protein conserved in bacteria [Function unknown].	2.01134e-76
NC_019771.1\|WP_015216835.1\|5520452_5522120_+\|L-aspartate-oxidase	gnl\|CDD\|236010	PRK07395, PRK07395, L-aspartate oxidase; Provisional.	0
NC_019771.1\|WP_015216826.1\|5505201_5505882_-\|uracil-DNA-glycosylase	gnl\|CDD\|235376	PRK05254, PRK05254, uracil-DNA glycosylase; Provisional.	4.46265e-132
NC_019771.1\|WP_015216839.1\|5526419_5527268_-\|BtpA/SgcQ-family-protein	gnl\|CDD\|223511	COG0434, SgcQ, Predicted TIM-barrel enzyme [General function prediction only].	2.87415e-138
NC_019771.1\|WP_015216829.1\|5507704_5512549_-\|PAS-domain-S-box-protein	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.48002e-51
NC_019771.1\|WP_015216821.1\|5501577_5502870_+\|AmpG-family-muropeptide-MFS-transporter	gnl\|CDD\|341039	cd17486, MFS_AmpG_like, AmpG and similar transporters of the Major Facilitator Superfamily. AmpG acts as an inner membrane permease in the beta-lactamase induction system and in peptidoglycan recycling. It transports meuropeptide from the periplasm into the cytosol in gram-negative bacteria, which is essential for the induction of the ampC encoding beta-lactamase. The AmpG family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.3315e-156
NC_019771.1\|WP_015216831.1\|5516225_5517551_-\|TIGR03279-family-radical-SAM-protein	gnl\|CDD\|132322	TIGR03279, cyano_FeS_chp, putative radical SAM enzyme, TIGR03279 family. Members of this protein family are predicted radical SAM enzymes of unknown function, apparently restricted to and universal across the Cyanobacteria. The high trusted cutoff score for this model, 700 bits, excludes homologs from other lineages. This exclusion seems justified because a significant number of sequence positions are simultaneously unique to and invariant across the Cyanobacteria, suggesting a specialized, conserved function, perhaps related to photosynthesis. A distantly related protein family, TIGR03278, in universal in and restricted to archaeal methanogens, and may be linked to methanogenesis.	0
NC_019771.1\|WP_015216828.1\|5506484_5507696_-\|EAL-domain-containing-response-regulator	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	8.00419e-110
NC_019771.1\|WP_015216838.1\|5525369_5526359_-\|vitamin-K-epoxide-reductase-family-protein	gnl\|CDD\|240599	cd12916, VKOR_1, Vitamin K epoxide reductase family in bacteria and plants. This family includes vitamin K epoxide reductase (VKOR) present in bacteria and plant. VKOR (also named VKORC1) is an integral membrane protein that catalyzes the reduction of vitamin K 2,3-epoxide and vitamin K to vitamin K hydroquinone, an essential co-factor subsequently used in the gamma-carboxylation of glutamic acid residues in blood coagulation enzymes. All homologs of VKOR contain an active site CXXC motif, which is switched between reduced and disulfide-bonded states during the reaction cycle. In some plant and bacterial homologs, the VKOR domain is fused with domains of the thioredoxin family of oxidoreductases which may function as redox partners in initiating the reduction cascade.	1.01558e-51
NC_019771.1\|WP_015216840.1\|5528059_5529379_+\|30S-ribosomal-protein-S12-methylthiotransferase-RimO	gnl\|CDD\|273453	TIGR01125, Ribosomal_protein_S12_methylthiotransferase_RimO, ribosomal protein S12 methylthiotransferase RimO. Members of this protein are the methylthiotransferase RimO, which modifies a conserved Asp residue in ribosomal protein S12. This clade of radical SAM family proteins is closely related to the tRNA modification bifunctional enzyme MiaB (see TIGR01574), and it catalyzes the same two types of reactions: a radical-mechanism sulfur insertion, and a methylation of the inserted sulfur. This clade spans alpha and gamma proteobacteria, cyano bacteria, Deinococcus, Porphyromonas, Aquifex, Helicobacter, Campylobacter, Thermotoga, Chlamydia, Streptococcus coelicolor and Clostridium, but does not include most other gram positive bacteria, archaea or eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification].	0
NC_019771.1\|WP_015216833.1\|5518748_5519516_+\|DUF3120-domain-containing-protein	gnl\|CDD\|371465	pfam11318, DUF3120, Protein of unknown function (DUF3120). This family of proteins with unknown function appears to be restricted to Cyanobacteria.	2.19981e-109
NC_019771.1\|WP_042465395.1\|5503595_5504045_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.75656e-17
NC_019771.1\|WP_015216827.1\|5505878_5506268_-\|phosphomannose-isomerase-type-II-C-terminal-cupin-domain	gnl\|CDD\|380343	cd02213, cupin_PMI_typeII_C, Phosphomannose isomerase type II, C-terminal cupin domain. This family includes the C-terminal cupin domain of mannose-6-phosphate isomerases (MPIs) which have been classified broadly into two groups, type I and type II, based on domain organization. This family contains type II phosphomannose isomerase (also known as PMI-GDP, phosphomannose isomerase/GDP-D-mannose pyrophosphorylase), a bifunctional enzyme with two domains that catalyze the first and third steps in the GDP-mannose pathway in which fructose 6-phosphate is converted to GDP-D-mannose. The N-terminal domain catalyzes the first and rate-limiting step, the isomerization from D-fructose-6-phosphate to D-mannose-6-phosphate, while the C-terminal cupin domain (represented in this alignment model) converts mannose 1-phosphate to GDP-D-mannose in the final step of the reaction. Although these two domains occur together in one protein in most organisms, they occur as separate proteins in certain cyanobacterial organisms. Also, although type I and type II MPIs have no overall sequence similarity, they share a conserved catalytic motif.	1.3572e-46
NC_019771.1\|WP_015216837.1\|5522865_5525094_-\|CHASE2-domain-containing-protein	gnl\|CDD\|226703	COG4252, COG4252, Predicted transmembrane sensor domain [Signal transduction mechanisms].	2.54604e-133
NC_019771.1\|WP_015216825.1\|5504140_5504899_+\|HEAT-repeat-domain-containing-protein	gnl\|CDD\|224331	COG1413, COG1413, FOG: HEAT repeat [Energy production and conversion].	1.41953e-26
NC_019771.1\|WP_015216832.1\|5517625_5518561_-\|undecaprenyl-diphosphate-phosphatase	gnl\|CDD\|376891	pfam02673, BacA, Bacitracin resistance protein BacA. Bacitracin resistance protein (BacA) is a putative undecaprenol kinase. BacA confers resistance to bacitracin, probably by phosphorylation of undecaprenol. More recent studies show that BacA has undecaprenyl pyrophosphate phosphatase activity. Undecaprenyl phosphate is a key lipid intermediate involved in the synthesis of various bacterial cell wall polymers. Bacitracin, a mixture of related cyclic polypeptide antibiotics, is used to treat surface tissue infections. Its primary mode of action is the inhibition of bacterial cell wall synthesis through sequestration of the essential carrier lipid undecaprenyl pyrophosphate, C55-PP, resulting in the loss of cell integrity and lysis. The characteristic phosphatase sequence-motif in this family is likely to be the PGxSRSGG, compared with the PSGH of the PAP family of phosphatases.	1.24096e-86

>NC_019771.1|WP_150111048.1|5513137_5516017_-|family-10-glycosylhydrolase
MCEEYLVKNHIKIKIASLFIVNINFLVFNLLEILPTKAATEVNVLGVIKSQENSNQWKGITNRLQAVGAKYCVIPLDSVKNVADLGKQQVLLLPNVEVLTPVQAIALEEWMSRGGRLIASGPIGSLSTPGVRQLLRTLLGGYWAFSLSQAQELQPAKTNSPEWANRKELFGKVIGAVMISDHPSTQVAAVWNSQDQQSAVLTTERSTLLGWRLGTDTAATADLDTAWLKAALSRYLKWPNKKIVGEVANCSPASENLPTTTQSPVLGNINPPTTRNKPRRVVSQKKPNLPKTRTQPRQVTSQKKPNLPKTRTKPRQVTSRKKPNLPRTRTQPRQATSRNPETQPKPVSQNFQEAIDQLETAVRLDVLPNSNQPIDSKDAVALQKELENLIGRVKSAHLAASVHGYSNVNKLQTLKSESEKLASTGLETTDLSLEQNLAQAREVAKNIPVLISQKKYALARQEWLKTKTNLWQQFPINQRIAQPEIRAVWLDRGTIVKAENEAGLVQIFDRLTQAGINTIFFETVNAGYTIYPSQVAPEQNPLIKDWDPLAVAVKLAHARGMELHAWVWTFAAGNRPHNEIINVNPDYPGPVLAANPNWANYDQRGQMIPSGQTKPFLDPANPEVRQYLLKLYEEILTRYQVDGLHLDYIRYPFQDPFVGRIYGYGKAAREQFQQQTGVDPINIAPTQRDLWQKWTVFRTEQVDSFVAEVSQMLRKKRANLILSVAVFPLPEYERVQKIQQRWEVWARRGDIDLVVPMTYALDTPRFQRLAQPWINSTKLGSTLLVPGIRLLSLPTVGAFDQLQMLRDLPVSGYALFAADNFNNKLDEIFSNTQGKLQDSKNDPIPQRQPFRTAALRYMALEKEWQLVRENDQLQMSANTISTFKNQSQELQSILNQLAVSPSPRNLISARASLNRFQSKFRIWLIVKAKENPYQVKVWENRLLTIERLLRYGERRVINK
>NC_019771.1|WP_015216829.1|5507704_5512549_-|PAS-domain-S-box-protein
MQASPHYFVLKSLKSVIYCSALTVTPETYVLDVIAAMPVSPADRLHQNGAIAPESISPIARQYQCVLIKSASEIVGCLTPQDIVQLVASGADLKNVQISEVMQTSVIKLNMQSFNTLTTVISSLSQSKLQLFAVVDEQDRLNSIITPEGICLALEAVPLTAAFCNGVHRADTLHSAYRKNGQIVENQLLQSQQMLQLIIDTIPHNIFWKDVNSVFLGCNRNFAKMVGLENPQDIVGKTDYDLVANREQADFYRSCDAQVMKTNQPQYQTITPHQQADGKQLWLETNKVPLYNNGGNVVGILGTLENITEQKQALDALEKSEERFRFLAESIPQQVWIARPDGSLEYINQRTLDYFACTAEQILNWKWQEWVHPDDLPNSLTAWNISLATGTNYEVEFRLLQQSSGTYRWHLGRALALRNQQGQIINWFGTNTDIHDRVTAEVALRDSERRYHTIAKVSPVGLFCTDAAGHFHYANDRWCEIAGRVPDKIGGMTWVSTIHPEDQERIQAEWDQSVTQNLSFCSEYRFQHPNGEVRWVVGQIVAECSESGEEITYIGTVTDISEKQAVLRDSEAIRRNHQRVEAALVERVRLADFRSEVDAILTQTETLENMMRGCTDALVKHLHAAFARIWILNTEEQVLELQVNSGKYTDIDENHRLVAVGQFKIGLIAQEGKPHLTNSVQDDPHISNQEWAKQEGIVAFAGYPLIVEGETIGVIAMFSCQALTENTFSSMGIVADEIALGIKRKQTEAALRESEERFRNLVEATTDWVWEVDENCIYTYVSPKVRDILGYEPQEVLGKQPFELMPPAEAERVIKIFLPLFEDRQSFKCVENIQYHQDGHLVVMETNGVPIFDVDGNFGGYRGIDRDITIRKQEAAKLWEMQQQLQAILDNFPAVMYLLDPENKYLLVNHQYEKLFNITQAQIVGKSVYDVWPHDVAQAFAVSNSQVMAGGIPLEIEEVAPHPDGLHTYLSVKFPLKDVNDTPYAVCSISTDITSRKRDQEELRQSEEYFRLLVEGVKDYAIYMLDPEGRVMSWNSGAECITGYQASEIIGRDFSCFFRPEDVLSNIPKQQLKIAAINGRCECESVFLRKDGSHFWANCILTPLHDETGKQRGFSKVTRDITERKLTEKSLLRLHKAIESTSDAISITDITGKAVYVNPAFVEVFDYTFSQLNSCGGLSANFTKQETFNQVFKTVQRGEPWRGEITMQTRGHHNVQVDLRIDAIKDSTNKIVSFVSIYTDITQRKLIEEGLRLRDRAIAASSNGIVIADVTSPDSSIIYVNPAFERMTGYSAAEVMGQNFRLLQGVDIHQPGLQELSTAMQAGQDCTVILRNYRQDGSLFWQELNISPVYDTDGYLTHYIGIQTDITNRKQLEQELRVALEKEKELNELKSRFISMTSHEFRTPLSTILSSSELLEHYRHKWTQEKQLTHLRRIQSAVQRITEMLNDILMIGKAEAGKLEYKPLLFDLVAYCRHLVEELQLNLKNQHLLSFSSEFESISCYMDDKLVGHILSNLLSNALKYSPDGTLVKFTLSCENRQAVFEIQDQGIGIPEEDIPRLFESFHRAKNVGNILGTGLGLAIVKKCVDIHQGSIHVISQVGWGTKFTVKLPMKNII
>NC_019771.1|WP_015216828.1|5506484_5507696_-|EAL-domain-containing-response-regulator
MHKILIIEDEESVRENILDLLIAEDFETIAAANGRTGLNLAMSEIPDLILCDMMMPELNGYEVLTALKKEPITATIPFIFLTAKAAKSDFRQGMDMGADDYLTKPFTRSELLSAILNKLEKYANLRKYLSRQTAIHKLTPRMQLLDKKLHRAIIDNHFEEFEIYYQPIIDIYSGKIIGAESLLRWQSHELGVISPTEFIPIAESNGLIMTIGKWVLKKVCQQIKIWRVAGINSLTIAVNLSAIEFNQPDLIAQIIDLIKSNNLEMPGLEIELTESMIMQDVNSAIATMNQLRSLGIKIAVDDFGTGYSSLSYLKYFPINTLKIDRCFIQNITQDHQKSAITKALIQMGHSLNLKIVAEGVETESELSFLRQQNCDAIQGFLFSCALPALEFEQFVLSNKSFFI
>NC_019771.1|WP_015216827.1|5505878_5506268_-|phosphomannose-isomerase-type-II-C-terminal-cupin-domain
MNQHENELQSNLDNSSCHSGERYWGNVEVLEEGENYRISRVEIKPRHGIKAQIHYHRHEHWVVVSGVAKVTCGDEEILLNSNQSTYVPAATLHKVENPGSITLVILEIQNGEYLGEDDIERPFELTSVQ
>NC_019771.1|WP_015216826.1|5505201_5505882_-|uracil-DNA-glycosylase
MKNLQLPIDWQAVLGDELTKPYFDKLQAFLVEDGLSHNIYPPEKDVFSAFELTPYEKVNVLLLGQDPYHNENQAHGLCFSVKPGIKPPPSLMNIFKELKADVGLDIFNHGYLVQWAKQGILMLNAVLTVRANTPNSHKNKGWEIFTDAVINKVNEKSESVVFVLWGGYAQKKLKLIDTNRHKVIQSAHPSPFSARNGFFGSKPFSAINAALVDWGKPEIDWQVGNW
>NC_019771.1|WP_015216825.1|5504140_5504899_+|HEAT-repeat-domain-containing-protein
MYDEDDLSLLDAEVELESPLDRIEPLTAESEVAKPDPELMLALLTNPQSQQRMLAARAFCDIEYERAIPHLISLLTDNCPLVRVSAAYALGRNPSQDAVEPLITQLNRDWNGYVRKGIVWALGNCRDRRSLAPLAESLRTDISAVRLWAASALAQMAGVGYEVIVGAIPPLIEALVQDPIAAVRSNCAWTIGQLCKELPSNVVYATAIDALIQAFAEDQDLGVREDAKAALLGVGDPRGLQLIETLEQEGWF
>NC_019771.1|WP_042465395.1|5503595_5504045_+|GNAT-family-N-acetyltransferase
MQQTYQEMFSHQDFSHLALTVEQYFSTDTPLWWVDEEASEKGAGKKEEFTQSPITYYQSPSPIACLWVGNAIDQIKGDRHTHIFLLYVTPEHRRQGIGRALMNHVENWAKQRGDRQIALQVFQSNTAALQLYHHQGYQTQSLWMVKPLH
>NC_019771.1|WP_015216823.1|5503333_5503486_+|hypothetical-protein
MMAIFRQYIAPLIAVLIFTFALVAVSARIFLPSDMAAPAPIGMVIRNSGY
>NC_019771.1|WP_015216822.1|5502854_5503256_+|hypothetical-protein
MGNQVVILVGTFVLIVTGLLLGYVLSQLVLGFLGFNLLTLLGTISLILIFGTLYYVLFWQLRREPSQPFKNGIPKQVDEEVTGNYLKNRLIARLSGDVAAAERLIEQAKQNYPGMPENWYCERVLDDLDREQR
>NC_019771.1|WP_015216821.1|5501577_5502870_+|AmpG-family-muropeptide-MFS-transporter
MNPVQSLLQVFGSRKMAALILLGFSSGLPLFLTSKTLQAWMTVENVDLTAIGLFSLVGVPYSLKFLWSPLLDWFTLPFLGRRRGWLITIQIGLLIAIACMALQQPKQALQLLAINAVAIAFLSATQDIAADAYRTDILEQLEMGAGAAVFVLGYRIALLLTGSLALILADNIPWSSVYLLMSVGMVIGIIATLFAPEPKEITPPESLTAAVILPFGEFIQRQGILQALLTLLFIVLYKLGDSFVNNMSTPFLLQTGFTQTDIGAIQGGMGLIATIVGTLAGGAFLSKIGLNRSLWVFGALQAVSNLAYLVLAQVGKNYQVLLLTINIENFCAGLGTAAFVAFLMNMCNQRYSATQYALLSSFMAVSRDILVAPAGSLAKNTGWPLFFVISILAAVPGLLLLPFFAPWNPTPEAVTRPGIEPEEEDIWGTK
>NC_019771.1|WP_015216831.1|5516225_5517551_-|TIGR03279-family-radical-SAM-protein
MTTIHPAKITKVLTESIAAEIGFEAGDAIVAINGTQPRDLIDYQFLCADEVLELEVLDTAGKTHHIEIEKDYDDDLGLEFETALFDGLIQCNNRCPFCFIDQQPPGKRSSLYFKDDDYRLSFLYGSYLTLTNLSEKEWQRIEQMRLSPLYVSVHATEPEIRTRLLKNNRAGQILKQLKWFQERRLQIHAQVVVCPGINDGKHLEQTLRDLTSFHTGEIPAVASIAVVPVGLTRFRPQEDELVPVTQEKAREVISQVKSLSHEFRKKFGSSVAWLADEWFLIAGEELPSEAEYEEYPQIDNGVGSIRLFIKQFTQAAHELLPLKVSPQKKLTWVVGNAVEQAFKPIVKQLNAVEGLEINMKALCSDYWGQSISVTGLLTGHDLLLKLNGQDLGEGILLPSVMLKHGELIFLDDVSVENVANQLNTKIFPVAGVEDLINTCIS
>NC_019771.1|WP_015216832.1|5517625_5518561_-|undecaprenyl-diphosphate-phosphatase
MAIILATDSIDLLFPVWWQILQVEVPSEAATNGVNLVQGLMQAFILGIVQGITEFLPISSTAHLLIVTKVFAWKELGSKDFVDAIQFGSVIAILWYFWKLISSILKGAIKTLKDKDWEREEWKITVGIAVGTMPALTIGFLLKDVLPDSALIIAIMSVVMAILLGLAEKIGTRKRGFDSLQIRDGILVGLGQTLALIPGVSRSGSTLTTALFLGLERETAAKFSFLLGFPTLTIATLYKSLKIFKLFQAQELPNNIVLLLIVGIISTFIFSYLSIAFLIRYLQTKNTMVFVWYRLAFGISILLAIAFGWQG
>NC_019771.1|WP_015216833.1|5518748_5519516_+|DUF3120-domain-containing-protein
MINNTLSSYTTNNTDLHTTDTGYGGIKELESTLSLSASFPAAISRKQTWLVFAAAMFLVTVPVFIEAPLVRSLPNVSLVMTGFWVWLSLTLMSRPQTYIWGDLLLGFSWSWLTGAIYWGWLRWEPLWHLPIESIGLPFAIWCLWRNWGKVGNWFYLGSLFGTVLTDVYFYLVDLMPYWRQIMRTDTAGASQILKNALAQVLTPWGETWAIILALALLTVGIVSLGKTQWHWYAFSGAVLSTILVDSLFLLAAVFA
>NC_019771.1|WP_042466168.1|5519892_5520321_+|photosystem-II-complex-extrinsic-protein-PsbU
MKGLVRLLTVFSLLLGSWGLLGTTQIAQAASFSNVTLFQVPVLAISRQNRADAKLGTEFGKKIDLNNTNIAAFQQYPGLYPTLAKKIISNAPYQKVEDVLNLPGLSESQKSRLQANFDNFTVTEYEPNFNEGDDRINNGIYR
>NC_019771.1|WP_015216835.1|5520452_5522120_+|L-aspartate-oxidase
MSQIDIPSQFDVLVVGAGAAGLYTALCLPDSLRVGLITKETVTLSASDWAQGGIAAAVSPEDSPQLHIEDTLKAGAGLCDIEAVEFLAENAPSCIESLVNLGVAFDRHGSSLAFTLEAAHSRPRVLHAADTTGREVTTTLAAQVLHRHNIQIIQQALALSLWIEPETGRCQGISLFYQGQVTWVRAGAVVLATGGGGQVFAQTTNPAVSTGDGVAIAWRAGAILRDLEFVQFHPTALTKPGRFLISEAVRGEGAHLIDNEGRRFAFDYHPAGELAPRDVVSRAIFSHLQNTAVDLATAHVWLDMRSIPPEKIRHRFPNIIQVCQHSGIDVFNEPVPVAPAAHYWMGGILTDLMNRTNIPGLYAVGETASTGVHGANRLASNSLLECIVFGAQMADVENELLSANQIPAESISNPLSCVFSASEWQNQQEYLAAIREKLPRLVWQSAGICREESGLESAIATIESWQQDFTNLPLSQFLQSLRPTESANFNLPNIDQQLRLWAETRNLLDVAYLILKSAAFRTESRGGHYRLDYPQPNLNWQVHTIVQNRSWWKSH
>NC_019771.1|WP_171815815.1|5522176_5522347_-|hypothetical-protein
MTEVKKIFHSFIVHDFSDTESPRTKTQGANEFALDIDMYSPPDYGAPDSQHGSGTR
>NC_019771.1|WP_015216837.1|5522865_5525094_-|CHASE2-domain-containing-protein
MNQQLSSHLVRLVFEVKQVLNQGRRELMIASWIAICVMILRSVGLLQSLELDTLDKFFRLRPYELPDERITIVAIDETSVRQVGSWPIPDEIIAQVLFKLKEYKPRAIGLDIYRDLAVKSGYKKLENAYKSIPNLIGIQLLAHNKKQSVLPPSILNERNQVGFNNILYDPDGKVRRSLLYSHVNNQAHESFALKLALLYLKSEGITPQTAKGNHQYLQLGKAVFTRFESNNGGYVGADARGYQILSNFPKPRCHNVSVGLCNYRHISLTDVLAGRIPEDWIRDRIILIGSTAPSLQDFVFIPYSSHLMDTSAAQPIAGVQLQAYFINELISAALQGRPLLKVCPDYIENLWIFIWSLIGMLIIWQIRQPKKSVFIFLLSGFALNLTVYLAFLSGWWIPIIPAWLTFSSSAIAMIFHINYIQQELKRSKEFLHQIINAIPDPIFVKNQQHQLIVLNEAYCRFIGYSYNLLIEKLDYNFFPQHEADIFRKQDDIVFQTQQPQEHEEELTNANGKTYLIATKRSLHKDAAGNFFLVGIIRDITQSKKIEEQLKRTAADLSHSNYALKLQENHLRQLAYHDSLTGLSNRKFFLEQLDESLNWSQTNHLMLGLLFIDLDGFKEVNDTLGHEIGDRLLVIIAQRLNSSLRTSDTVSRLGGDEFTVILRAISNFQIAAKVAEKLLSVITEPIVLDGHTTTVSASIGISIYPTNSQNSEDLIKQADTAMYQAKHLGKNRYEFTETVMNAE
>NC_019771.1|WP_015216838.1|5525369_5526359_-|vitamin-K-epoxide-reductase-family-protein
MIRRRSTPWIHKWSRPLIGAIAGCGVLITGYLTFEKLTGRSAACVAEVGTKGCNDVLSSPWATVFGQPLALFGLLAYISMLIFALAPLALNSGENNKSSKQLENLTWWLLLMGAIAMSVFSGYLMYILASQIKALCPYCIGSALFSLSMLVITIIGRDWEDIGQIFFTAIIIGMMTLIGTLGIYAGVNPSGDIAESTSGKPQQITFTPTAEPNPEFGWKITTKSGESEIALAEHLVKIGAKEYSAYWCPHCHEQKLLFGQEAEKIIDDNIKVECANDSPKAKLDLCQAAKIQSFPTWIINGKTYTGVQNLDELAKITDYKGSRNFKYFR
>NC_019771.1|WP_015216839.1|5526419_5527268_-|BtpA/SgcQ-family-protein
MDLYQLFKTRTPIIGVVHLLPLPTSPRWGGSLKAVIDRAEQEATALASGGVDSIIVENFFDAPFTKNQVDPAVVSAMTVVVQRIQNLVTLPIGLNVLRNDGKSAMAIASCVKAQFIRVNVLTGVMATDQGLIEGEAHQLLRYRRELGSDVKILADVLVKHARPLSSPNLTVAVKDTIERGLADGVILSGWATGSPPNLEDLELACGAAAGTPVFIGSGANWENIDTLMQAANGVIVSSSLKRHGQISQPIDPIRVSQFVEAAHRSWNSKGESKSISSVKLHS
>NC_019771.1|WP_015216840.1|5528059_5529379_+|30S-ribosomal-protein-S12-methylthiotransferase-RimO
MGEKPTIAISHLGCEKNRIDTEHMLGLLVEAGYSVDTNEELADYVIVNTCSFIEAAREESVRTLVELAEANKKVVITGCMAQHFQEQLLEELPEAVAVVGTGDYHKIVNVIERVEQGERVKLISAEPTYIADETTPRYRTTTEGVAYLRVAEGCDYRCAFCIIPYLRGNQRSRTIESIVAEAKQLANQGVKEIILISQITTNYGLDIYGQPKLAELLRALGKVDVPWIRMHYAYPTGLTPDVIAAIQETPNVLPYLDLPLQHSHPEMLRSMNRPWQGRVNDGIIDRIKTALPSSVLRTTFIVGFPGETQEQFDHLLEFTERHEFDHVGVFTFSAEEGTPAYKLPNQIPAEVMAERRDQLMALQQPISFHKNQQEVGKIVDVLIEQENPESGELIGRSGRFSPEVDGQVYVKGESRLGTIVPVKIHNADAYDLYGQIVNS

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Crispr_ID: NC_019771_21

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_21

5738603-5740678

Orphan

A:N

Consensus_repeat	Method
ATTGCAATTTCTATTACTCCCTATTAGGGA----TTGAAAC	PILER-CR
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	CRISPRCasFinder
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	CRT

28 spacers

The CRISPR arrays of NC_019771_21

>merge|NC_019771|21|5738603-5740678|PILER-CR,CRISPRCasFinder,CRT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACAAAACTGGAGAATGTACCTTGAATGCCGAGGGAGTATGGGAATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACAAGTAAAAGCTGGGTATTTGCCTCAACTTTTTCCCAGTAATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACAATCCTGAGAAACCGTGGGAAGATTCGGTTAACTCATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACATCTTAGTCATGAAAAATGGATCGCTTTATGGAGACAATATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACAAAAGCATCTATTCCCAATTCTTTAAGTACTGGTAATTGATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACTTCACTATCACCCAGTACCCTGATTCTCCTTGGATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACCACATATTTTACTCTCCCCTTCTAAAACATTCTATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACATTATGGCAACAGGCATTAAGTCCATTGTCCATTTATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACTAGATTTTCAGAGAATTGGAAAAGCTGTCGTTGCTTATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACTCCGCTTCTAGCTGAGTAGGGAAAACGCAGTCAATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACGTTACTGTTCCAGTTACAGGCGCGGGGTATGCACTTAGGATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACGTCCGGTGAGGGGAAGTCCAGTGGTGGTACATATCATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACTTATAGATTTTCTACTAGATATTATTCTCTAATATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACAAAGAAATATCTTCGCCAGTCCGCAATTGCATTATTTTTGGGATATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACTTTAATATTAAATACCCCAGAATTTTCATACCAAATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACTTTACACACCTGATACAAATTGCTTTGCAAAAAAGATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACTCCACAAAACCCAGAAAGAGACTTTTTCCAACAGCAAATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACTCCGCACTTCCTGACAATGAAAAAGTTATTTTATGATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACAACACTTTAGGTCAACCTAGGCTTAAGGGGAATATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACGCTACATGGTTTGTTACTCCCAAAAAGTCAGATAATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACCAAATCAATAATATTCATAAAACGCCCTGAGAAAAATTAATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACAACCGAAATACTTGAGCTACAACGGCAACGGCAATAATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACTATTAGATTATCTATTAGATAATTTACCCATACCATAAAATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACTTTAGCGAATTGTGATTGATAAGTTTTTCTTTGAATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACTTTTTCCAAATTAGGCATGAAGACATCTTCCAGATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACTGGACGCTCAAAACCAATGCGCCAACCCCAGTTATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACGAAGGAAGTATTTTTACAAATATATTTGCTACAATTGCAATTTCTATTACTCCCTATTAGGGATTGAAACAAAACTTTAGTATATTAACTGATGCCACCTACTTATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC

>NC_019771|21|10|5738603-5740678|PILER-CR
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AAAACTGGAGAATGTACCTTGAATGCCGAGGGAGTATGGGA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AAGTAAAAGCTGGGTATTTGCCTCAACTTTTTCCCAGTA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AATCCTGAGAAACCGTGGGAAGATTCGGTTAACTC
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	ATCTTAGTCATGAAAAATGGATCGCTTTATGGAGACAAT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AAAAGCATCTATTCCCAATTCTTTAAGTACTGGTAATTG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTCACTATCACCCAGTACCCTGATTCTCCTTGG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	CACATATTTTACTCTCCCCTTCTAAAACATTCT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	ATTATGGCAACAGGCATTAAGTCCATTGTCCATTT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TAGATTTTCAGAGAATTGGAAAAGCTGTCGTTGCTT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TCCGCTTCTAGCTGAGTAGGGAAAACGCAGTCA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	GTTACTGTTCCAGTTACAGGCGCGGGGTATGCACTTAGG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	GTCCGGTGAGGGGAAGTCCAGTGGTGGTACATATC
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTATAGATTTTCTACTAGATATTATTCTCTAAT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AAAGAAATATCTTCGCCAGTCCGCAATTGCATTATTTTTGGGAT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTTAATATTAAATACCCCAGAATTTTCATACCAA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTTACACACCTGATACAAATTGCTTTGCAAAAAAG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TCCACAAAACCCAGAAAGAGACTTTTTCCAACAGCAA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TCCGCACTTCCTGACAATGAAAAAGTTATTTTATG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AACACTTTAGGTCAACCTAGGCTTAAGGGGAAT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	GCTACATGGTTTGTTACTCCCAAAAAGTCAGATA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	CAAATCAATAATATTCATAAAACGCCCTGAGAAAAATTA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AACCGAAATACTTGAGCTACAACGGCAACGGCAATA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TATTAGATTATCTATTAGATAATTTACCCATACCATAAA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTTAGCGAATTGTGATTGATAAGTTTTTCTTTGA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTTTTCCAAATTAGGCATGAAGACATCTTCCAG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TGGACGCTCAAAACCAATGCGCCAACCCCAGTT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	GAAGGAAGTATTTTTACAAATATATTTGCTACA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AAAACTTTAGTATATTAACTGATGCCACCTACTT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC

>NC_019771|21|21|5738603-5740678|CRISPRCasFinder
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AAAACTGGAGAATGTACCTTGAATGCCGAGGGAGTATGGGA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AAGTAAAAGCTGGGTATTTGCCTCAACTTTTTCCCAGTA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AATCCTGAGAAACCGTGGGAAGATTCGGTTAACTC
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	ATCTTAGTCATGAAAAATGGATCGCTTTATGGAGACAAT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AAAAGCATCTATTCCCAATTCTTTAAGTACTGGTAATTG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTCACTATCACCCAGTACCCTGATTCTCCTTGG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	CACATATTTTACTCTCCCCTTCTAAAACATTCT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	ATTATGGCAACAGGCATTAAGTCCATTGTCCATTT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TAGATTTTCAGAGAATTGGAAAAGCTGTCGTTGCTT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TCCGCTTCTAGCTGAGTAGGGAAAACGCAGTCA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	GTTACTGTTCCAGTTACAGGCGCGGGGTATGCACTTAGG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	GTCCGGTGAGGGGAAGTCCAGTGGTGGTACATATC
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTATAGATTTTCTACTAGATATTATTCTCTAAT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AAAGAAATATCTTCGCCAGTCCGCAATTGCATTATTTTTGGGAT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTTAATATTAAATACCCCAGAATTTTCATACCAA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTTACACACCTGATACAAATTGCTTTGCAAAAAAG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TCCACAAAACCCAGAAAGAGACTTTTTCCAACAGCAA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TCCGCACTTCCTGACAATGAAAAAGTTATTTTATG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AACACTTTAGGTCAACCTAGGCTTAAGGGGAAT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	GCTACATGGTTTGTTACTCCCAAAAAGTCAGATA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	CAAATCAATAATATTCATAAAACGCCCTGAGAAAAATTA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AACCGAAATACTTGAGCTACAACGGCAACGGCAATA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TATTAGATTATCTATTAGATAATTTACCCATACCATAAA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTTAGCGAATTGTGATTGATAAGTTTTTCTTTGA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTTTTCCAAATTAGGCATGAAGACATCTTCCAG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TGGACGCTCAAAACCAATGCGCCAACCCCAGTT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	GAAGGAAGTATTTTTACAAATATATTTGCTACA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AAAACTTTAGTATATTAACTGATGCCACCTACTT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC

>NC_019771|21|7|5738603-5740678|CRT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AAAACTGGAGAATGTACCTTGAATGCCGAGGGAGTATGGGA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AAGTAAAAGCTGGGTATTTGCCTCAACTTTTTCCCAGTA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AATCCTGAGAAACCGTGGGAAGATTCGGTTAACTC
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	ATCTTAGTCATGAAAAATGGATCGCTTTATGGAGACAAT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AAAAGCATCTATTCCCAATTCTTTAAGTACTGGTAATTG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTCACTATCACCCAGTACCCTGATTCTCCTTGG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	CACATATTTTACTCTCCCCTTCTAAAACATTCT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	ATTATGGCAACAGGCATTAAGTCCATTGTCCATTT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TAGATTTTCAGAGAATTGGAAAAGCTGTCGTTGCTT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TCCGCTTCTAGCTGAGTAGGGAAAACGCAGTCA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	GTTACTGTTCCAGTTACAGGCGCGGGGTATGCACTTAGG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	GTCCGGTGAGGGGAAGTCCAGTGGTGGTACATATC
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTATAGATTTTCTACTAGATATTATTCTCTAAT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AAAGAAATATCTTCGCCAGTCCGCAATTGCATTATTTTTGGGAT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTTAATATTAAATACCCCAGAATTTTCATACCAA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTTACACACCTGATACAAATTGCTTTGCAAAAAAG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TCCACAAAACCCAGAAAGAGACTTTTTCCAACAGCAA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TCCGCACTTCCTGACAATGAAAAAGTTATTTTATG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AACACTTTAGGTCAACCTAGGCTTAAGGGGAAT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	GCTACATGGTTTGTTACTCCCAAAAAGTCAGATA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	CAAATCAATAATATTCATAAAACGCCCTGAGAAAAATTA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AACCGAAATACTTGAGCTACAACGGCAACGGCAATA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TATTAGATTATCTATTAGATAATTTACCCATACCATAAA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTTAGCGAATTGTGATTGATAAGTTTTTCTTTGA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TTTTTCCAAATTAGGCATGAAGACATCTTCCAG
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	TGGACGCTCAAAACCAATGCGCCAACCCCAGTT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	GAAGGAAGTATTTTTACAAATATATTTGCTACA
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC	AAAACTTTAGTATATTAACTGATGCCACCTACTT
ATTGCAATTTCTATTACTCCCTATTAGGGATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015217031.1\|5751806_5751926_-\|photosystem-II-reaction-center-protein-Ycf12	unknown	unknown	gnl\|CDD\|237469
NC_019771.1\|WP_015217030.1\|5749505_5751566_+\|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl\|CDD\|273193
NC_019771.1\|WP_015217028.1\|5747927_5748353_+\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015217021.1\|5735326_5736562_+\|DUF445-domain-containing-protein	unknown	unknown	gnl\|CDD\|226834
NC_019771.1\|WP_015217014.1\|5726423_5726621_-\|50S-ribosomal-protein-L35	unknown	unknown	gnl\|CDD\|234676
NC_019771.1\|WP_015217025.1\|5742664_5743576_+\|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl\|CDD\|213023
NC_019771.1\|WP_015217015.1\|5726673_5727381_-\|hypothetical-protein	unknown	unknown	unknown
NC_019771.1\|WP_015217017.1\|5730144_5731848_+\|glycosyltransferase-family-39-protein	unknown	unknown	gnl\|CDD\|227621
NC_019771.1\|WP_015217029.1\|5748415_5749174_-\|Uma2-family-endonuclease	unknown	unknown	gnl\|CDD\|368559
NC_019771.1\|WP_042465442.1\|5733450_5734401_+\|response-regulator	unknown	unknown	gnl\|CDD\|381113
NC_019771.1\|WP_015217018.1\|5732013_5733099_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375541
NC_019771.1\|WP_015217023.1\|5737270_5738362_+\|alanine-dehydrogenase	unknown	unknown	gnl\|CDD\|240630
NC_019771.1\|WP_015217033.1\|5752535_5752940_+\|TMEM165/GDT1-family-protein	unknown	unknown	gnl\|CDD\|225030
NC_019771.1\|WP_015217032.1\|5752091_5752442_+\|YkgJ-family-cysteine-cluster-protein	unknown	unknown	gnl\|CDD\|223799
NC_019771.1\|WP_015217027.1\|5745544_5746633_-\|chorismate-synthase	unknown	unknown	gnl\|CDD\|215402
NC_019771.1\|WP_015217024.1\|5740868_5742347_+\|NACHT-domain-containing-protein	unknown	unknown	gnl\|CDD\|366375
NC_019771.1\|WP_015217016.1\|5727587_5730020_-\|ATP-dependent-helicase	unknown	unknown	gnl\|CDD\|223288
NC_019771.1\|WP_015217026.1\|5743831_5744932_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NC_019771.1\|WP_015217020.1\|5734516_5735206_+\|bifunctional-demethylmenaquinone-methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol-methylase-UbiE	unknown	unknown	gnl\|CDD\|234689
NC_019771.1\|WP_015217022.1\|5736793_5736964_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|177653

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015217031.1\|5751806_5751926_-\|photosystem-II-reaction-center-protein-Ycf12	gnl\|CDD\|237469	PRK13686, PRK13686, photosystem II reaction center protein Ycf12.	2.64584e-12
NC_019771.1\|WP_015217030.1\|5749505_5751566_+\|single-stranded-DNA-specific-exonuclease-RecJ	gnl\|CDD\|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	3.29389e-166
NC_019771.1\|WP_015217021.1\|5735326_5736562_+\|DUF445-domain-containing-protein	gnl\|CDD\|226834	COG4399, COG4399, Uncharacterized protein conserved in bacteria [Function unknown].	4.57437e-141
NC_019771.1\|WP_015217014.1\|5726423_5726621_-\|50S-ribosomal-protein-L35	gnl\|CDD\|234676	PRK00172, rpmI, 50S ribosomal protein L35; Reviewed.	1.00282e-23
NC_019771.1\|WP_015217025.1\|5742664_5743576_+\|polysaccharide-deacetylase-family-protein	gnl\|CDD\|213023	cd10918, CE4_NodB_like_5s_6s, Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands. This family belongs to the large and functionally diverse carbohydrate esterase 4 (CE4) superfamily, whose members show strong sequence similarity with some variability due to their distinct carbohydrate substrates. It includes bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, hemin storage system HmsF protein in gram-negative species, intercellular adhesion proteins IcaB, and many uncharacterized prokaryotic polysaccharide deacetylases. It also includes a putative polysaccharide deacetylase YxkH encoded by the Bacillus subtilis yxkH gene, which is one of six polysaccharide deacetylase gene homologs present in the Bacillus subtilis genome. Sequence comparison shows all family members contain a conserved domain similar to the catalytic NodB homology domain of rhizobial NodB-like proteins, which consists of a deformed (beta/alpha)8 barrel fold with 6 or 7 strands. However, in this family, most proteins have 5 strands and some have 6 strands. Moreover, long insertions are found in many family members, whose function remains unknown.	1.88677e-31
NC_019771.1\|WP_015217017.1\|5730144_5731848_+\|glycosyltransferase-family-39-protein	gnl\|CDD\|227621	COG5305, COG5305, Predicted membrane protein [Function unknown].	1.71024e-33
NC_019771.1\|WP_015217029.1\|5748415_5749174_-\|Uma2-family-endonuclease	gnl\|CDD\|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	2.11467e-06
NC_019771.1\|WP_042465442.1\|5733450_5734401_+\|response-regulator	gnl\|CDD\|381113	cd17569, REC_HupR-like, phosphoacceptor receiver (REC) domain of hydrogen uptake protein regulator (HupR) and similar domains. This family is composed of mostly uncharacterized response regulators with similarity to the REC domains of response regulator components of two-component systems that regulates hydrogenase activity, including HupR and HoxA. HupR is part of the HupT/HupR system that controls the synthesis of the membrane-bound [NiFe]hydrogenase, HupSL, of the photosynthetic bacterium Rhodobacter capsulatus. It contains an N-terminal REC domain, a central sigma-54 interaction domain that lacks ATPase activity, and a C-terminal DNA-binding domain. Members of this family contain a REC domain and various output domains including the cyclase homology domain (CHD) and the c-di-GMP phosphodiesterase domains, HD-GYP and EAL. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.63992e-56
NC_019771.1\|WP_015217018.1\|5732013_5733099_-\|hypothetical-protein	gnl\|CDD\|375541	pfam18087, RuBisCo_chap_C, Rubisco Assembly chaperone C-terminal domain. This is the C-terminal domain, also known as the beta domain, of Rubsico Assembly Chaperone protein (Raf1). Raf1 is necessary for rubisco to catalyze the rate-limiting step of carbon fixation through carboxylating the five-carbon sugar substrate ribulose-1,5-bisphosphate. The beta domains primary function is dimerization, which is critical for Raf1 to achieve the necessary avidity for complex formation with RbcL (the large complex sub-unbit of Rubsico) assembly intermediates. The beta domain is also involved, to a small extent, in binding to RbcL with use of the lustiness near the beta domain's conserved top surface.	1.05443e-79
NC_019771.1\|WP_015217023.1\|5737270_5738362_+\|alanine-dehydrogenase	gnl\|CDD\|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NC_019771.1\|WP_015217033.1\|5752535_5752940_+\|TMEM165/GDT1-family-protein	gnl\|CDD\|225030	COG2119, COG2119, Predicted membrane protein [Function unknown].	2.37993e-32
NC_019771.1\|WP_015217032.1\|5752091_5752442_+\|YkgJ-family-cysteine-cluster-protein	gnl\|CDD\|223799	COG0727, COG0727, Predicted Fe-S-cluster oxidoreductase [General function prediction only].	8.33123e-12
NC_019771.1\|WP_015217027.1\|5745544_5746633_-\|chorismate-synthase	gnl\|CDD\|215402	PLN02754, PLN02754, chorismate synthase.	0
NC_019771.1\|WP_015217024.1\|5740868_5742347_+\|NACHT-domain-containing-protein	gnl\|CDD\|366375	pfam00931, NB-ARC, NB-ARC domain.	7.79478e-08
NC_019771.1\|WP_015217016.1\|5727587_5730020_-\|ATP-dependent-helicase	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	1.30865e-79
NC_019771.1\|WP_015217026.1\|5743831_5744932_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.65317e-72
NC_019771.1\|WP_015217020.1\|5734516_5735206_+\|bifunctional-demethylmenaquinone-methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol-methylase-UbiE	gnl\|CDD\|234689	PRK00216, ubiE, bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE.	3.45253e-120
NC_019771.1\|WP_015217022.1\|5736793_5736964_-\|hypothetical-protein	gnl\|CDD\|177653	PLN00014, PLN00014, light-harvesting-like protein 3; Provisional.	6.70581e-05

>NC_019771.1|WP_015217023.1|5737270_5738362_+|alanine-dehydrogenase
MEIGVPKETKDQEFRVGLSPSSVRVLRENGHSIFVQTQAGTGAGFTDEDYISAGAEIVSTLEAAWNRELVIKVKEPLVSEYNLLQKGQLLFTYLHLAADRKLTEHLLDCGISAIAYETVEQAGVNRLPLLTPMSIIAGRLAVQFGARFLERQQGGKGVLLGGVPGVKAGKVVILGGGVVGTEAAKIAVGMGAIVQILDVNVERLSYLETLFGSRVELLYSNSAHIETAVKEANLLIGAVLIPGRRAPILVSRDLVKQMHPGSVIVDVAVDQGGCVETLHPTSHTSPVYIDEGVVHYGVPNMPGAVPWTSTQALNNSTLPYAVQLANLGIKALDVNPALAKGLNVQNHRLIHPAVQEVFPDLVS
>NC_019771.1|WP_015217022.1|5736793_5736964_-|hypothetical-protein
MTQPQPSVNPKLEDPKFGFNEYSERLNGRAAMIGFILMVLIEYLTNQGVLSWLGLK
>NC_019771.1|WP_015217021.1|5735326_5736562_+|DUF445-domain-containing-protein
MDWSHLWLYVSPPILGGVIGYFTNDIAIKMLFRPYQAIYILGWRVPFTPGLIPRNQERLAKNISDTIMGSLLTPDELQKLARRLLQTERVKGAILWLLQLAIEQVQADKNQKSVKIIAGILRDLLGESLPRLLKVLARQENFLEAQINQIFDQILLEFQLSEEQSTRLADWLLEVVLPPDVLRQAIVDFLTDRTIQTIDDSFREKTSGTYWVVANLFGLRNTLTRLRTFCLDEKEATNKRLQELIQDLQMRDRFKKLLQDLSFQNLPIGTVRQLRKTTRDSVRHYLQNSGSDLLKELTESADWENIAGLLLKRLSNSPVVSTSLEVVSEELALILERYLERDLEAIVTQVIPILSIDQVIIDRVKSTSPADLEAAIEGIVKNELQAIVTLGGILGFVVGLFQVGFLFLSRY
>NC_019771.1|WP_015217020.1|5734516_5735206_+|bifunctional-demethylmenaquinone-methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol-methylase-UbiE
MSNEIRDIFDRIAPVYDQLNDWLSLGQHRIWKEMTVKWSAVKPGDTCLDLCCGSGDLTFRLARYAGVTGKVYGVDFSCNLLTVAKERCHKYYPQASITWLEADVLNLPFDDNQFDAITMGYGLRNVKDIPLSLQEIYRVLKPGGKAAILDFHKPSNAILRTFQQWYLDNLVVPLATNLGVKEEYAYISPSLDRFPIGQEQVRIAQKIGFVNTIHYPISNDMMGVLVVNK
>NC_019771.1|WP_042465442.1|5733450_5734401_+|response-regulator
MDNLNMDIEQVRSQASNRERPTKLKILVVDDEPDNLDLLYRTFRRDFNVLKADSGINALQLLEEEGEVAVIISDQRMPEMKGTEFLSRTLPQFPDTVRIILTGFTDIEDLVEAINSGQVFKYITKPWDSGELKDVVQRAAATYDLLKQRTEELRRANAQMDLLTVLVEVTQAASSLEATLAPIAKACSKTFNADGCIVQLLEGEALVGTQGVYSETGVIENWLSQDVLAKAAIATGQIQSSLNIPKDPNLSSLAYYQAAGVQAHLIIPIIYRQKMLGVLSLQWQKPCILRTDELKLIHLSVELLAIALSSSYTANG
>NC_019771.1|WP_015217018.1|5732013_5733099_-|hypothetical-protein
MTELPTNTQDTENATNDTAQELLVKLRQKQGNWVEWGTAIAYLQKNGYNPQEIFEATGFEPSQQNQVIVGSQVYSCLEKFGASEATKAYYGERASDILYELRLLTQEDRAAAADLIFLHKLDVDEAREIAKSIRDFSRFPAPPTGFTANPGDAVAYQIWKLARQNSDLQERSRLIAKALRFVHSQTARKQIEQLLMDFTAVVQRPAPILPFFRLESDEELPRIVPVVGELPLTPQDIQAVPIITEIEPFRIVKFAGEQAWVSLPGWQVLRSAEDPVVIIASSDIFPNPTLTKTEPVLVVIDRAQREWDISSYFVVDNSGEIDFQWFDTAPENTILGKIIVILRPKKVLDEEFTKDSWQIDE
>NC_019771.1|WP_015217017.1|5730144_5731848_+|glycosyltransferase-family-39-protein
MINRKLFIHDLGLTGTIPALGIAIAIGAILRFWHLDLKPLWLDEIITAIFSLGKNYRDLPLDVLFPLNQIQTIFAFQPGVSCSQIATNLANYSTHPPLFFCWMYSWLGFLHPLSIEWMAKLRSLPALFGVATILAIYGVNRIAFSPTSGIMAAFLMALSPFAVYLSQEARHYTLPMLIITLALFLLMQIQQDIFYQQRLRFWVWFLWAIINSIGLYVHYFFSIAFIAEVATLLMLIYRGKSNIFKLRQVYLYLIISTCSIIISFMPWILVILSHLRSSETNWLPSAHHVEPIYQTLITWVLMIITLPVENQPLLMAIFCGFLMVVFMIWTGWQVLPNLKLLWLKSKTHLPTFTLLSFTFFVLLQFFLIAYLLGKDITVVPRYHFVYYPSFCALLAVSLEKVKIPKFVFLLVGLISCIFVLSNLAFQKPFQPDKVAQNMNFEPAVPLMLVVGYENYQDVAAGLSFAVALEQLRSHEITSQLQKDSLIFLDKSPDFSAFSNKLSQISMADISQFNLWFVGSSMRKRDYPQNLTLTSGKTTCKIEPIQHYRTGQFPYQLYRCSNSSGTSK
>NC_019771.1|WP_015217016.1|5727587_5730020_-|ATP-dependent-helicase
MSKDNFTDLVEQKSLELEANQQSSLAKLNDNIVAIRDSLRPGQKQMADWEHGSLAVSAVPGAGKSRGMADAAAIAIARQYQHSLSTGNNYRRQLIVVTFTRSAAANIKAKIRECLRDKLSLPQTGFAVYTLHGLALNIASRHPNLSGLQLENVTLITPNQSHRFIRQAVEQWIIHNPEQYSHLLAGKQFDGEETEKLRRQSVLRTEVLPDLAYTVIHEAKSSGITPQQLKKWSQKTTDKYAILQVAAGLYEEYENLMRRRSPSDMSPDFIDYDDMILAALRVLENDSARRIEQNQVFAVFEDEAQDSSPLQTQLLEILASGGEEAGEQGAGGRGQGDGGDFDSSLLRTPQLNLVRVGDPNQAINSTFTPADPIYFRDFCKKCHLDQRLATMDQAGRSTRIIIAAANFALEWVNNQWSTTNKGETPFLVQTIHPVDINDPQTNANPAPVGKGLELYTPVDIHQTVELLSQRVVELFTQDPQSCAAVLVRENRQGRWLGEALEPICKEHNIKLYDVGERERRSHVPQEILSLLQFCDRPHSPGKLKAALDVLVQRQLIPTQDLNALASIPEEFLYPGPLAAPQTDIVQKTAHLCRSLLRARLELPLYQIISFFALTLNYDQAELATADKLAERVNQQLFGNTSMEAMLSALSEIVSSERFESVDTENLDEQYTQPGQLTIITMHKAKGLDWDYVFLPFLHENLIPGRFWVPPQSQFLGDFTLSEVARAQIRAVLHTKAIPNISQAWEDAKYLKMAEEYRLLYVAMTRAKRLLWMSAAQQAPFTWNKPHNLQASAPCPVFAALKRQFPKNVVK
>NC_019771.1|WP_015217015.1|5726673_5727381_-|hypothetical-protein
MSFHLKNIGKLPQSIVLTLALSGLLACGLDISNNQTSVAIPSPEQTQLAQNRNNLPRDISRAVLRDAAKRSGVKMPDLKITQVTVTTFGNPCIFRFGEICTKEYRPIRGWKVVVQVKDQSWTYHVNQPGSQILLDPKVNVSATSQLPKDIADKVVSDASKRSGLPQNAIKITQATQQTFSNACVFSFGEVCTQQFDPIEGWIVIVKVKNQSWTYHVDKTGASIVLDPKVATSTKN
>NC_019771.1|WP_015217014.1|5726423_5726621_-|50S-ribosomal-protein-L35
MPKLKTRKAAAKRFRATGTGKIVRRKAFKSHLLEHKSSNKKRGLRQSALVCERDADNVRLMLPYL
>NC_019771.1|WP_015217024.1|5740868_5742347_+|NACHT-domain-containing-protein
MPNSIKASTTGLEIVDKARLRLGWTKTSTARWWQDAHTSKATLRRFWQGDRIQKEIFIAICQAVGINEWETISDSSDTQLDITTPLIDWNEAPNIESFYGRNAELLQLEEWINNGCKLINIIGIGGIGKTSLALAIADSLQSQFDCLIWKSLYHTPSLNFLIDYLLNSFNQSAVQNIQKDTFKLISYLQQHRCLLILDGLDAVLSNSELTKFIQESSLHRHQSCIITTSREKQNSLEVNTKTVCTLTLNGLAKTEALELLQSRGFTGKELGLSALIQLYRGNPLAIKLVIPLIESVFGGNVAAFLNQNTIVVSDRLRVILKQQFEQLSGLERDILYWLAIWQEPISFCRLQTHLLLSVDPAMVLEGIMALEKRSLLEKWNSEQEPAFTLQPLVMKVATDELVENAVQEIRQVVRTNDIHYFHILRTHWLLRPGTDDIAGDRILNQLCEKLYPVYSSTLPQILNQILPLLQNQSPLAIGYIACNITALINRNN
>NC_019771.1|WP_015217025.1|5742664_5743576_+|polysaccharide-deacetylase-family-protein
MTEDNNDQVSNSSKNQKFPITIFLLMAMIFPLLKLGSNPPTIPILGFHGIVKFQNNLRQSSNLEMDYKQQEIEKLLEYLVTQDYWFLTTQDLYDFFLTKSKEIPYEHRNKKMIMLTFDDGYKTIYTNLLPILSKLEKKYGKKIKVVLFISPSTLANNDGIPATHLRCQELRKGWQKGFFDIQSHGNNHQNLTKISQPEVISELLLARIKLRKCLDDLDPEQKVASHIAYPYGAYNKQVEKYVTKYYLSGYLYNDKLLNYTCLKDNYKIPRLMVNRTKSSQELIGIIQSFSTDPQESLKKDICK
>NC_019771.1|WP_015217026.1|5743831_5744932_+|Gfo/Idh/MocA-family-oxidoreductase
MIGVAVVGTGFGQKVHIPAFQAHHKTGIVAIYHRDINKAQSIATTNNIPHASDNLTEILALPEVQAVSISTPPFLHYEMAKQVLQSGKHLLLEKPTTLNVTEAKELYYLAKNKGVIATVDFEFRFVPGWQFFAQLLSSGYVGNLRLIKIDWLGASRADVSRPWNWYSNQEQGGGALGSLGSHAFDYINWLFGPVHKLNAYLSTAIPERSDPVNGKLKPVNTDDTCMLSLELANGTPCQVSISAVVHAPRTHRVEVYGDKGTLVLGSDNQKDYIHGFQVWGSQIGQPLTEIEIPQQLLFPQYYADGRICAFLRVVDEWIKGIETKQEITPSLREGVYSQLLMDLSHQSHELKTWVNVPNLATFLNYV
>NC_019771.1|WP_015217027.1|5745544_5746633_-|chorismate-synthase
MGSTFGHLFRITTFGESHGGGVGVIIDGCPPQLEISAEEIQFELDRRRPGQSKITTPRKEADTCEILSGVFEGKTLGTPISILVRNKDARSQDYDEMEQKYRPSHADATYDAKYGLRNWQGGGRSSARETIGRVAAGAIAKKILRQVANVEVIAYVKCIKDLESVIDTDTVTLEQVESNIVRCPDGEIANRMIELIEQTGRDGNSIGGVVECVVRNVPKGLGEPVFDKLEADLAKAVMSLPASKGFEIGSGFAGTLLTGFEHNDEFYIDENGEIRTVTNRSGGIQGGISNGENIILRVAFKPTATIRKEQKTVTREGEETLLAAKGRHDPCVLPRAVPMVDAMVALVLCDHLLRHYGQCKVL
>NC_019771.1|WP_015217028.1|5747927_5748353_+|hypothetical-protein
MSKLISATLIVTTLLLTPTNNSQVTLAGTCASNCGAKPLQFTPGQYIRVQVANRTPRVLKLEKLPEMRRITLQPGQEYRVDRESATEPNFSILFWDDTGRSLQANVSKPNFGTLRLELRPSEKFPGYRSLYILNDGKVNVF
>NC_019771.1|WP_015217029.1|5748415_5749174_-|Uma2-family-endonuclease
MVAQISEIKFPTELVISWEALPDDFQLEDEPVENTGQPILAGALRESLEIAGFIQSKMLIASNFGLCATLNGQFIAKAPDWLYVPTVKEILAERKSYTPNLEGDIPAIVMEFLSDNDGGEYSFKRTYPPGKWFFYEQILQVPVYVIFDPDGGLLEFYQLENGRYELKQPDENGRHWIDSMGLFLGTWRGEKETRIGYWLRWWDEAGNLLLWSVEQISQERQRAEQERQEKERLIAYLKSQGIDPDNLPTAMP
>NC_019771.1|WP_015217030.1|5749505_5751566_+|single-stranded-DNA-specific-exonuclease-RecJ
MTNDQPIKRLPNQRWQIAPANPELAQNLADLTNISPIISQLLINRGMKTPEDAQVFLSPETLDLPSPLEDFPDLAVSVELLEDAIANQEKIAICGDYDADGMTSTALLLRSLRALGANVDYAIPSRMHEGYGINKRIIEEFHSEGVGLVLTVDNGISAFEPIARARELGLKVIITDHHDIPPILPPANAILNPKLIAESSPYRGVAGVGVAYILAVCLAQQLGQIKGLVQPMLALFTLGTIADLAPLTGVNRRWVKRGLKLLPKSTLPGVQALIQVAGVQAIGAEEQGSRGAGEKVQNPKSLKPEDIGFRLGPRINAIGRIGNPQTVIELLTTDDMGLALERAMQCEQINIQRQQMCEQIEQEAIALVEDLYVNSLQKNRVLVVVKDNWHHGVIGIVASRLLERYGVPVFIGTFEDEGVIRGSARGIPEFNVFAALEYCRDLLGKFGGHKAAGGFSLPADNLLSVRSRLSEFANQCLEPQHLKPLLKIDAQANLNQINQDLYQQLNILHPCGIDNPDPIFWTPNAQVIEQQIVGKGHIKLTLAQTVDNIKYQIKAIAWRWRDYFPLPARVDIAYKLRENHFNDKISIEMELVGVRLPAQSPIFSTPPSQKLRANFEYKQRQYTCGVYQNGVDSELRIKNPEGKVLVMQPGDNHGLLGSSRDDAKKVNLSLPQYDGIIQAAIQALDS
>NC_019771.1|WP_015217031.1|5751806_5751926_-|photosystem-II-reaction-center-protein-Ycf12
MEALANINWEVIFQLTSVGLIIIAGPVVIFVLAFRNGNL
>NC_019771.1|WP_015217032.1|5752091_5752442_+|YkgJ-family-cysteine-cluster-protein
MATWQCVKQCGACCHLDPADRPDLEDYLLPEELAVYMSMVGEGGWCINFNHITRECGIYDDRPRFCRVEAETFEEMYGIEPEELSDFAIDCCRQQIEGVYGDRSLEIIRFDQAVGF
>NC_019771.1|WP_015217033.1|5752535_5752940_+|TMEM165/GDT1-family-protein
MKLDSTPVSISDLSQTQNQLDLKDTSDYLLEPVIEDSPKKQDSALMVFGTTFITIFLAEIGDKTQLSTLLMSAESHQPWVVFIGSGAALITTSLLGVLLGGWIASKLSPKTVEKSAGVMLLLISVMLFWDVFIG

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Crispr_ID: NC_019771_22

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_22

5832140-5832391

Orphan

A:N

Consensus_repeat	Method
CTTTACAAACCCACTTCCCCGCAAGGGGATGGAAAC	PILER-CR
CTTTACAAACCCACTTCCCCGCAAGGGGATGGAAAC	CRISPRCasFinder
CTTTACAAACCCACTTCCCCGCAAGGGGATGGAAAC	CRT

3 spacers

The CRISPR arrays of NC_019771_22

>merge|NC_019771|22|5832140-5832391|PILER-CR,CRISPRCasFinder,CRT
CTTTACAAACCCACTTCCCCGCAAGGGGATGGAAACGTCCATTCTTCTTCAGTTTCTTTAGCAGAATCAACTATCTTTACAAACCCACTTCCCCGCAAGGGGATGGAAACATACAGTGGTATTCAGGTTACCACTGACCTGCTTTACAAACCCACTTCCCCGCAAGGGGATGGAAACTTTCATTAACCCAACCATTTCACCACATTGTTGTTCTGACTTTACAAACCCACTTCCCCGCAAGGGGATGGAAAC

>NC_019771|22|11|5832140-5832391|PILER-CR
CTTTACAAACCCACTTCCCCGCAAGGGGATGGAAAC	GTCCATTCTTCTTCAGTTTCTTTAGCAGAATCAACTAT
CTTTACAAACCCACTTCCCCGCAAGGGGATGGAAAC	ATACAGTGGTATTCAGGTTACCACTGACCTG
CTTTACAAACCCACTTCCCCGCAAGGGGATGGAAAC	TTTCATTAACCCAACCATTTCACCACATTGTTGTTCTGA
CTTTACAAACCCACTTCCCCGCAAGGGGATGGAAAC

>NC_019771|22|22|5832140-5832391|CRISPRCasFinder
CTTTACAAACCCACTTCCCCGCAAGGGGATGGAAAC	GTCCATTCTTCTTCAGTTTCTTTAGCAGAATCAACTAT
CTTTACAAACCCACTTCCCCGCAAGGGGATGGAAAC	ATACAGTGGTATTCAGGTTACCACTGACCTG
CTTTACAAACCCACTTCCCCGCAAGGGGATGGAAAC	TTTCATTAACCCAACCATTTCACCACATTGTTGTTCTGA
CTTTACAAACCCACTTCCCCGCAAGGGGATGGAAAC

>NC_019771|22|8|5832140-5832391|CRT
CTTTACAAACCCACTTCCCCGCAAGGGGATGGAAAC	GTCCATTCTTCTTCAGTTTCTTTAGCAGAATCAACTAT
CTTTACAAACCCACTTCCCCGCAAGGGGATGGAAAC	ATACAGTGGTATTCAGGTTACCACTGACCTG
CTTTACAAACCCACTTCCCCGCAAGGGGATGGAAAC	TTTCATTAACCCAACCATTTCACCACATTGTTGTTCTGA
CTTTACAAACCCACTTCCCCGCAAGGGGATGGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_042466196.1\|5838805_5839921_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|369777
NC_019771.1\|WP_015217101.1\|5836821_5838111_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270451
NC_019771.1\|WP_015217096.1\|5829568_5831770_+\|HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|131525
NC_019771.1\|WP_015217094.1\|5824918_5826340_+\|precorrin-3B-C(17)-methyltransferase	unknown	unknown	gnl\|CDD\|381173
NC_019771.1\|WP_015217090.1\|5820658_5821405_+\|creatininase-family-protein	unknown	unknown	gnl\|CDD\|224320
NC_019771.1\|WP_015217104.1\|5839980_5840868_-\|glycosyl-transferase-family-14	unknown	unknown	gnl\|CDD\|367100
NC_019771.1\|WP_015217093.1\|5824217_5824922_+\|precorrin-2-C(20)-methyltransferase	unknown	unknown	gnl\|CDD\|180341
NC_019771.1\|WP_015217100.1\|5836116_5836821_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|372616
NC_019771.1\|WP_015217105.1\|5840908_5841832_-\|LD-carboxypeptidase	unknown	unknown	gnl\|CDD\|224534
NC_019771.1\|WP_015213182.1\|5828132_5829215_+\|photosystem-II-q(b)-protein	unknown	unknown	gnl\|CDD\|130221
NC_019771.1\|WP_015217095.1\|5827567_5827918_+\|histidine-triad-nucleotide-binding-protein	unknown	unknown	gnl\|CDD\|238607
NC_019771.1\|WP_015217089.1\|5818790_5820320_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|379138
NC_019771.1\|WP_015217102.1\|5838120_5838783_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|132997
NC_019771.1\|WP_015217099.1\|5834782_5835625_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227078
NC_019771.1\|WP_015217088.1\|5817845_5818580_+\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|223639
NC_019771.1\|WP_015217097.1\|5832565_5833132_+\|recombination-protein-RecR	unknown	unknown	gnl\|CDD\|234616
NC_019771.1\|WP_015217106.1\|5841881_5843039_-\|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|366659
NC_019771.1\|WP_015217091.1\|5822045_5823596_+\|precorrin-3B-synthase	unknown	unknown	gnl\|CDD\|236573
NC_019771.1\|WP_015217092.1\|5823588_5824215_+\|precorrin-8X-methylmutase	unknown	unknown	gnl\|CDD\|181352
NC_019771.1\|WP_015217098.1\|5833457_5834801_-\|O-antigen-ligase-family-protein	unknown	unknown	gnl\|CDD\|225844

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_042466196.1\|5838805_5839921_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	3.38847e-10
NC_019771.1\|WP_015217101.1\|5836821_5838111_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270451	cd14748, PBP2_UgpB, The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold. This group includes the periplasmic component of an ABC transport system specific for sn-glycerol-3-phosphate (G3P) and closely related proteins from archaea and bacteria. Under phophate starvation conditions, Escherichia coli can utilize G3P as phosphate source when exclusively imported by an ATP-binding cassette (ABC) transporter composed of the periplasmic binding protein, UgpB, the transmembrane subunits, UgpA and UgpE, and a homodimer of the nucleotide binding subunit, UgpC. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.86172e-94
NC_019771.1\|WP_015217096.1\|5829568_5831770_+\|HAD-IIB-family-hydrolase	gnl\|CDD\|131525	TIGR02472, putative_sucrose-phosphate_synthase, sucrose-phosphate synthase, putative, glycosyltransferase domain. This family consists of the N-terminal regions, or in some cases the entirety, of bacterial proteins closely related to plant sucrose-phosphate synthases (SPS). The C-terminal domain (TIGR02471), found with most members of this family, resembles both bona fide plant sucrose-phosphate phosphatases (SPP) and the SPP-like domain of plant SPS. At least two members of this family lack the SPP-like domain, which may have binding or regulatory rather than enzymatic activity by analogy to plant SPS. This enzyme produces sucrose 6-phosphate and UDP from UDP-glucose and D-fructose 6-phosphate, and may be encoded near the gene for fructokinase.	0
NC_019771.1\|WP_015217094.1\|5824918_5826340_+\|precorrin-3B-C(17)-methyltransferase	gnl\|CDD\|381173	cd11646, Precorrin_3B_C17_MT, Precorrin-3B C(17)-methyltransferase (also named CobJ or CbiH). Precorrin-3B C(17)-methyltransferase participates in the pathway toward the biosynthesis of cobalamin (vitamin B12). There are two distinct cobalamin biosynthetic pathways. The aerobic pathway requires oxygen, and cobalt is inserted late in the pathway; the anaerobic pathway does not require oxygen, and cobalt insertion is the first committed step towards cobalamin synthesis. This model includes CobJ of the aerobic pathway and CbiH of the anaerobic pathway, both as stand-alone enzymes and when CobJ or CbiH form part of bifunctional enzymes, such as in Mycobacterium tuberculosis CobIJ where CobJ fuses with a precorrin-2 C(20)-methyltransferase domain, or Bacillus megaterium CbiH60, where CbiH is fused to a nitrite and sulfite reductase-like domain. In the aerobic pathway, once CobG has generated precorrin-3b, CobJ catalyzes the methylation of precorrin-3b at C-17 to form precorrin-4 (the extruded methylated C-20 fragment is left attached as an acyl group at C-1). In the corresponding anaerobic pathway, CbiH carries out this ring contraction, using cobalt-precorrin-3b as a substrate to generate a tetramethylated delta-lactone.	1.40437e-130
NC_019771.1\|WP_015217090.1\|5820658_5821405_+\|creatininase-family-protein	gnl\|CDD\|224320	COG1402, COG1402, Uncharacterized protein, putative amidase [General function prediction only].	8.54582e-87
NC_019771.1\|WP_015217104.1\|5839980_5840868_-\|glycosyl-transferase-family-14	gnl\|CDD\|367100	pfam02485, Branch, Core-2/I-Branching enzyme. This is a family of two different beta-1,6-N-acetylglucosaminyltransferase enzymes, I-branching enzyme and core-2 branching enzyme. I-branching enzyme is responsible for the production of the blood group I-antigen during embryonic development. Core-2 branching enzyme forms crucial side-chain branches in O-glycans. This is a fmmily of glycosyl-transferases that are Type II membrane proteins that are found in the endoplasmic reticulum (ER) and Golgi apparatus.	2.24887e-18
NC_019771.1\|WP_015217093.1\|5824217_5824922_+\|precorrin-2-C(20)-methyltransferase	gnl\|CDD\|180341	PRK05990, PRK05990, precorrin-2 C(20)-methyltransferase; Reviewed.	1.27169e-98
NC_019771.1\|WP_015217100.1\|5836116_5836821_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|372616	pfam13489, Methyltransf_23, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.22889e-10
NC_019771.1\|WP_015217105.1\|5840908_5841832_-\|LD-carboxypeptidase	gnl\|CDD\|224534	COG1619, LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF [Defense mechanisms].	9.77566e-108
NC_019771.1\|WP_015213182.1\|5828132_5829215_+\|photosystem-II-q(b)-protein	gnl\|CDD\|130221	TIGR01151, Photosystem_QB_protein, photosystem II, DI subunit (also called Q(B)). This model describes the Photosystem II, DI subunit (also called Q(B)) in bacterial and its equivalents in chloroplast of algae and higher plants. Photosystem II is many ways functionally equivalent to bacterial reaction center. At the core of Photosystem II are several light harvesting cofactors including plastoquinones, pheophytins, phyloquinones etc. These cofactors are intimately associated with the polypeptides, which principally including subunits DI, DII, Cyt.b, Cyt.f and iron-sulphur protein. Together they participate in the electron transfer reactions that lead to the net production of the reducting equivalents in the form of NADPH, which are used for reduction of CO2 to carbohydrates(C6H1206). Phosystem II operates during oxygenic photosynthesis and principal electron donor is H2O. Although no structural data is presently available, a huge body of literature exits that describes function using a variety of biochemical and biophysical techniques. [Energy metabolism, Electron transport, Energy metabolism, Photosynthesis].	0
NC_019771.1\|WP_015217095.1\|5827567_5827918_+\|histidine-triad-nucleotide-binding-protein	gnl\|CDD\|238607	cd01276, PKCI_related, Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a hydrophobic residue) that is a signature for this family. No enzymatic activity has been reported however, for PKCI and its related members.	1.18905e-59
NC_019771.1\|WP_015217089.1\|5818790_5820320_+\|serine-hydrolase	gnl\|CDD\|379138	pfam13354, Beta-lactamase2, Beta-lactamase enzyme family. This family is closely related to Beta-lactamase, pfam00144, the serine beta-lactamase-like superfamily, which contains the distantly related pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	7.13003e-75
NC_019771.1\|WP_015217102.1\|5838120_5838783_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	8.46514e-33
NC_019771.1\|WP_015217099.1\|5834782_5835625_-\|hypothetical-protein	gnl\|CDD\|227078	COG4735, COG4735, Uncharacterized protein conserved in bacteria [Function unknown].	4.70507e-77
NC_019771.1\|WP_015217088.1\|5817845_5818580_+\|RNA-methyltransferase	gnl\|CDD\|223639	COG0565, LasT, rRNA methylase [Translation, ribosomal structure and biogenesis].	1.07828e-90
NC_019771.1\|WP_015217097.1\|5832565_5833132_+\|recombination-protein-RecR	gnl\|CDD\|234616	PRK00076, recR, recombination protein RecR; Reviewed.	6.5354e-114
NC_019771.1\|WP_015217106.1\|5841881_5843039_-\|HEAT-repeat-domain-containing-protein	gnl\|CDD\|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	2.30674e-11
NC_019771.1\|WP_015217091.1\|5822045_5823596_+\|precorrin-3B-synthase	gnl\|CDD\|236573	PRK09567, nirA, NirA family protein.	7.28995e-151
NC_019771.1\|WP_015217092.1\|5823588_5824215_+\|precorrin-8X-methylmutase	gnl\|CDD\|181352	PRK08285, cobH, precorrin-8X methylmutase; Reviewed.	1.28445e-129
NC_019771.1\|WP_015217098.1\|5833457_5834801_-\|O-antigen-ligase-family-protein	gnl\|CDD\|225844	COG3307, RfaL, Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane].	1.53048e-12

>NC_019771.1|WP_015217096.1|5829568_5831770_+|HAD-IIB-family-hydrolase
MSNSQGLYILLVSVHGLIRGHNLELGRDADTGGQTKYAVELATTLAKNPQVERVDLVTRLVNDPKVSPDYAQPIEILSDKAQIIRLACGPRRYLRKEVLWQHLDTFADELLRHIRKVGRIPNVIHTHYADAGYVGSRVAGWLGTPLVHTGHSLGRVKQQKLLEQGTKQEVIEDHFHISTRIEAEEITLGGAALVIASTNQEVEQQYSVYDRYQPERMVVIPPGVDLDRFYLPGDDWHNPPIQKELDRFLKDPQKPIIMAISRPAIRKNVSSLIKAYGEDPELRKLANLVIVLGKRDDIMTMESGPRQVFIEILQLIDRYDLYGHIAYPKHHNADDVPDLYRLTARTQGVFINPALTEPFGLTLIEASACGVPIIATADGGPRDILAACENGLLIDPLNIQEIQNALRKALTDKEQWQNWSSNGLVNVRKYFSWNSHVEKYLEKIHLFPQRRIQSLLSPLPASPATDHPEWNVPDTNRLPTADRFLVCEIDNTLLGDKEALEKLIQRIRNEGHTTGVGIATGRTLESTLSMLEEWRFPMPDLLITSAGSEIYYGPQIVTDTSWQKHIGYQWQAEAIRAAMKNIPGVELQPEEAQRKFKVSYFVDEAKAPNFREIIRHLRRHQLPVKGIYSHNMYLDLVPIRASKGDAIRYVALKWGLPVQRFLVAGASGNDETMLGGNTLGVVVGNYSQEIEKLRGYPQIYFAQGNYAWGILEALDYYDFFGNLSQKQPEMVTV
>NC_019771.1|WP_015213182.1|5828132_5829215_+|photosystem-II-q(b)-protein
MTTTIQQRSTANVWDRFCEWITSTENRIYIGWFGVLMIPTLLAATTCFIIAFIAAPPVDIDGIREPVAGSLIYGNNIISGAVVPSSNAIGLHFYPIWEAASLDEWLYNGGPYQLVIFHFLIGCACYLGRQWELSYRLGMRPWICVAYSAPLASATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLVRETTETESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVIGIWFTALGVSTMAFNLNGFNFNQSIIDSQGRVIGTWADVINRANLGMEVMHERNAHNFPLDLAAGDVAPVALTAPAING
>NC_019771.1|WP_015217095.1|5827567_5827918_+|histidine-triad-nucleotide-binding-protein
MSNTTDTIFSKIIRKEVPANIVYEDDLALAFTDVNPQAPVHILVIPKKPIVNLATAEPEDQALLGHLLLTVQKVAAQAGLENGYRVVMNTGVDGGQTVYHLHIHILGRRPMSWPPG
>NC_019771.1|WP_015217094.1|5824918_5826340_+|precorrin-3B-C(17)-methyltransferase
MNKRVAPAIVVLSQNSVALGRQIISVLPRAKLYGLANRTSDVDVSFTNFGETLRELFAAGTPLIGICAAGILIRTLAPLLTNKGQEPPVLAVAEDGSAVVPLLGGLSGVNDLARQIAAMLDIQAAITTTGDLRFRTALLSPPAGYHLANPEDAKKFIADLLAGAKVKLEGTASWLSESQLPIDPNGELTIQITENLGTPQPNCLVYHLEKIAAIDSETNEKQRGKLAIIGTGPGASKWMSSEVKEILNAATDLVGYKTYINLIGSLADGKHIHESDNREEEARAKMALDLAAEGKYVVVVSSGDPGIFAMATAVFEVLDRYNKPEWQNIDIQVAPGISAMQATAAAIGAPLGHDFCAISLSDILKPWEIIIQRITAAAQGDFVIAFYNPVSKERTWQLAAAKNILLQYRKPDTPVVLGRNLGRPGQVVKVITIEHLKPTDADMRTLIIVGSSQTRQMQSNHTKWVYTPRRYQT
>NC_019771.1|WP_015217093.1|5824217_5824922_+|precorrin-2-C(20)-methyltransferase
MNSGGRLYGIGVGPGDPELLTLKALRLLQSAPVIAYQSAIDKESIARKIVSPYLPGNQIEVLYHLPRALEPEKAKSIYDQEVEPIAAHLAAGRDVVVLCEGDPFFYGSFMYIFTRLSDQYQTEVVPGISSLMACPVSLGVPFTYYNDVLTVLPATLSTEMLTSHLLTTDAAAIMKLGRHFTKVRDILHQLGMASRAKYIERATTTQQRIVSLDEVNPEDVPYFSMIVIPTKQKL
>NC_019771.1|WP_015217092.1|5823588_5824215_+|precorrin-8X-methylmutase
MSNYIRDADEIYRNSFAIIRAEANLDILPPDVAKIAVRMIHACGMTDIVTDLGYSPRAVESGRKALASGAPILCDCRMVAEGVTRKRLPTNNQVICTLNDPEVPEIAKRLRNTRSAAALELWRFHLDGAIVAIGNAPTALFRILEMLDERVPRPALILGFPVGFVGAAESKAALAANSRNVPFLTLHGRRGGSAIAAAAINALATEEE
>NC_019771.1|WP_015217091.1|5822045_5823596_+|precorrin-3B-synthase
MLTASTACPGLFYNISAQDGILSRVRIPGGILNSEQCQFIANIADNCGGGYVDITNRANLQIREIKTGINIEILQRLQELGLGSANPTVDHIRNIMTSPTAGIDPQELIDTQPFVKAWDDYITEHPHLAGLSAKFSVGFDGGGKVSVQNCVNDITFAAVAENGNVYFQLYLSFGEKGQPPQNTGILLKPDECLPVLAVLADVYLDHIGVTSQRKRRLREVINDLGIENYLRLAFTSKSLTSQLPGEILHLAVDKFGVVSHYFCQLPITNYQLPAQTDMITVPANSIGIHPQKQAGLFYIGVVLPLGRWETWQMRRLADLAAKYGNGNLRVTPWQNLLVTDIPKKQVAEVETEITRLGLNISPTNIKTSLVACSGKRGCAASATETKDHALALADYLEYITLEHPINIHFSGCVKSCAQHQQADITLLGVRIQSENETMEGYQLYIGDGKLQKFGYQLYEYVTFAELPKIIATMLCVYKNQRLNLNESFREFVYRYDTSQLQRLFTVKSIPNPKSHV
>NC_019771.1|WP_015217090.1|5820658_5821405_+|creatininase-family-protein
MQLHLSTWPEVETYLQKSQGIIFPIGSTEQHGPTGLIGTDAICAEAISHGVAEETQGMVAPTINIGMALHHTAFPGTISLRPSTLILVVRDYITCLAKAGFTKFYFINGHGGNIATLKAAFSETYAHLEDLQLPSSQKVQCQIANWFMCGSVYKLAKELYGDQEGSHATPSEVAVTQYVYPEAIKQAPLSSKVASGHRIYGAANFRESYPDGRMGSNPALATPEHGKQFYDLAVGELSKGYLEFLNQE
>NC_019771.1|WP_015217089.1|5818790_5820320_+|serine-hydrolase
MSESSDKLIAISRQQPSQRRRRPRQNQKAGQTPVVKKPQQVIARGESVALTRLNNNNIIPPALPTEGRRPRSKIVMPTAVKPIPKSKGKMPQPGTAKLKTVRVPKQGKPKIDRRASRKTRLKPMARTILYTLRLLIVGIGLGAIVGTLLSVLDPANRITTSSSPSQTNAGPSQTQSPTNSSATASSLYLSQEIIPLKTDVQNLAAANPNLTPGVFMVDLDTGAYVDINSTASFSAASTIKVPILIAFFQDVDAGKIRLDEMLTVQQEMIAGGSGTLQTSTVGSQYTAIDVATKMITISDNTATNMLIARLGGQEVLNERFRSWGLATTIIRSPLPDLQGTNTTSPRELGNLIAALNQGNMVSMRSRDIMLDIMRRTQRNNLLPSGLGEGAKSYHKTGDIGTMLGDAGLIDIPTGKRYIAAVMVQRPNNDPTAEKLISAISSAAYQHFSQTAITPRTPTNNLPTNNFPQPVQPFIQPQGMTPIVPNGTVNNTPIGTYPAPVTTPQYYPPQ
>NC_019771.1|WP_015217088.1|5817845_5818580_+|RNA-methyltransferase
MGLAGIRIVLVEPAGPLNLGSIARVMKNFGLCNLVLVNPQCDRSSDDALKMAVHAKEILDSAIIVDTLPQALQGCVRAIATIGRDYSGEIPLENPRTTLPWLLEEPEKPVALIFGREDRGLSNEEINYAQKLVFIPTSPIYPSLNLATAVSICCYELSQLAEIFITPEIPPTEIAPLDIVEPYYQELESLLLSIGYIYPHTAASRMEKFRHLYNRAHIQTAEVAMLRGILRQIEWALKEAEGRR
>NC_019771.1|WP_015217097.1|5832565_5833132_+|recombination-protein-RecR
MEQLQRLPGVGPKSAQRLALHILKRPETEVEALAQAMIDAKKQIGLCQVCYHLSSEPVCEICRNPNRDNKIICVVADSRDVIALEKTREYKGKYHVLGGVISPMDGIGPEQLTVQPLVRRVSQQKPQEVIMAISPSVEGETTTLYIGQLLKPFTKVTRIAFGLPVGGDLEYADEVTLARALEGRRELD
>NC_019771.1|WP_015217098.1|5833457_5834801_-|O-antigen-ligase-family-protein
MLGASLNKAFYHPNSSLQPAWNCLQFGLLVFPLNPFLGAVTISLAALITWAKQYRTISRRPLHRGFAVLSLLLLITTGFASHQMEAFLGLFNLLPYFFVFAGLTALIQTAAQLRQISWIMVFGSLPVVMIGFGQLFFGWTFNLQFLWVLLDITISPGGVPLGRMSSVLMHANTLAAYLVTIFILGLGLWLENYQKLKVKNPPLKVSYRPIIFLTVAVFANFMALVLTNSRNGWLIAVFACVAYSFYQGWRLLVAGFLSMATSILLAAFAPLAIAQFFRRFVPYFIWARVNDDMYPDRPVAMMRKTQWEFAWNLTQQHPLTGSGLRSFSGLYKAEMQIDINHPHNLFLMLSAETGLITTLLFCSLLAWILIAAMQLLWNSKYIQLENRLIFFSYIITFIGWILFNTVDVTTFDIRLSTLFWVFLAALCGVIYQLAGVRSSEFGVRSSE
>NC_019771.1|WP_015217099.1|5834782_5835625_-|hypothetical-protein
MDELRTVLELATEEELQDLTAILFSRKFNPLDYVHTPEPIKVQSQDRQAWLNALEDRFRFLGADGMTVLRGHTCQVTYRQVLIQVCKYLKISYYHNLATVDLEAEVFLHLLGKVWKKLPAQEKQKLTERLQSHLLKSDIKQPLPLYLQKDPLGLIFKGGSALAVTSVLQPFVLKQIARQFATHFATYQVAKEAAITGTQVASKQFQSYVTVKMAQRGMTMSAARYGAVRSMFALIGPMMWGWFLADLGWRAIATNYGRIIPTIFTLAQIRLTRAECWEPA
>NC_019771.1|WP_015217100.1|5836116_5836821_+|methyltransferase-domain-containing-protein
MTNDTIAYTSDYFQTVAFDTDYQTLALSIVEIYNPKTVVEFGCGPGHLSRELAKLGVQVTSVDGYSQPDFAGLPVEFYPLNLNDPTAIANLFQDKHFDLAISLEVAEHLQPESSPIVINWLTKVAPVVVFSAAVPSQGGHGHINLHPRDYWHSLFTQSNFVICDRIREKLRAHSSVAPWYRYNVVDYVHVNHPQVPQLTEVIQRLIASESAAATAYYEESTKLYLLEQKTGICN
>NC_019771.1|WP_015217101.1|5836821_5838111_-|ABC-transporter-substrate-binding-protein
MKINISFSKIRSYFYLIVGIVLSLSLLFLSSCQTTLNKDNNVIHLTLWQSINPPTNRDVFEKLVEKFNHKHSDIQVESVYAEGLPKILTAVVGNAAPDILSFYPQLTGQFVELGAIVPLEKWFDQLSFKSEVIPNTLEELKLDGHLWSIPLYTSNMAIFYRPKLFEAAEIKSLPKTWEELREVAKKLTIDKSGDKQPEQHGILLPLGKGEWTVFSWFPFLLSAGGEIVTNGYPNLTNTGAITALKFWEDLIKDGSAILSGPERGYEEDDFLAGRVAMQITGPWTYITKSKVDYKLFPIPTNVEKATVIGGGNLYVMKTKPEREKAALKFLEFVVSEEFQTEWAVGTGFLPVNLKSAQSPAYQQYLNSKPWLKVFAEQTSVARARPIIAGYNRLSDSLGRAIESTLLGKSSAEQALKEAQERLEVIWKSN
>NC_019771.1|WP_015217102.1|5838120_5838783_-|glycosyltransferase-family-2-protein
MSPINFDIQPEVSIILCTYNRAKYLNQCIDSVIHQTFPNWELLVVDDGSNDHTFELVNLYLQKTQNIRYLKHKNRKLAYAKNVGIQASFSPYITFLDSDDTYAPNHIESRLNYLKSHSEIDLLQGGFFSKEEILVADYYEAGKTINLKKCVLGPTFFGKRKVFFELGGFDNIAYGEDTDFWERAEKIFKTQTITKPETYIYTRAETSITKSVLEKISSSD
>NC_019771.1|WP_042466196.1|5838805_5839921_-|class-I-SAM-dependent-methyltransferase
MIKTYVSNAFLKIEDSHLYAIFAWSQRTAEIINSKSWLTVLEIFVHEHCLEKAYQIFQQIKLASVPEKLIADLDQYQYLIPNAIIFLADGKITIFGKGFRSFIEKEMLFELGDISQETYQVLPELFFNNQLKDDLESIESIENIEAFRHLVEHLEKLGLLSPATNSIDWGDLKKAVPICQAFGLTRGTPVDRYYLSKYLEEIQTQISGNILEIGGIPKDKDFYEVNPGTSYQIMNIEPGPGIDIVGDAHDTSLIQPESFDSIVIFNVLEHCYAPWQIVENIYTWLKPGGKCFAMVPSAIRLHATPMDYWRPLPDAFAWMFRNFSQQKLYVYGNPTSVIASYHGIAVEELTSEELDAFHPDYPVATCIVAEK
>NC_019771.1|WP_015217104.1|5839980_5840868_-|glycosyl-transferase-family-14
MTISIGFILLTHRKPQQIHRLIAHLNKMFNYPRIVCHHDFSKSDLSVDTISKNVSFVRPHLQTQWGDFSIVEATVQAIKLMYESANSPDWFILLSGSDYPIKTAKEILGNLTSSKYDAHIHHEQIIYKVYQQNVKMSLIWQILAYQRYCSYELFSVPLIKNLKIRLEHPLLTKPFLPFSEELRCFAGGQWFSANQRAAEYIINFHSQKTALASHYRHRMFADESYFQTILANAPHLNLKNDDYRYVDWSTQGAHPKIMVMEDLPNLLTSSCHFARKFDLDVDSNILEQLDTITLA
>NC_019771.1|WP_015217105.1|5840908_5841832_-|LD-carboxypeptidase
MSNIQKCKSAILPQPLKPGDLLRVIAPSGALREFEAFNKSVEIWRCLSHGYRVEISPNIDHRHGYLAGTDAHRRQQLAAAWNDPECRGIICARGGFGSTRILEDWNWQQNIADPKWLIGFSDITALLWSLYNAGISGVHGAVMTTLVNEPEWSRQRLFDIVAGRAIAPLKGKGWGGGTVTGVLLPGNLTVATHLLGTPLLPNLDGVILAFEDVTEPPYRIDRMLTQWRLSGVLSKVRGIALGGFTKCDAPPHIPSLSIEEVLRERLGDLGIPIVSDLPFGHDSPNAALPVGVEVTLDAQEGILHHSP
>NC_019771.1|WP_015217106.1|5841881_5843039_-|HEAT-repeat-domain-containing-protein
MREIKKQENQVSSKQETEENKCLQLPIPHFILVFISCFCLGLYPNRSMAARPNLVPFQPTILNPGMTGSEVQVLQVQLKALGYYNDWIDGQYGLSTQNAVAKFQKAGVLKRKDGIADLTTQNSLKTALLGQNKCTTAPVSAPIPKANTTSPPSQINLIWWSLLGSGILGSVGAFVYLIKRVDKIQYSAISESQKLLSPSVQDHPKFFLSPAQTPPVSSSIASSIELLQPNASAMVAKLNIFDELIKELRVDDPNQRRKAIWNLGQQGDSRAIKPLVDLMIDADSQQYGLILSALAEIGSRTLKPLNRALVISLQNESPQVRKNAIRDLLRIYDMMGQMSQVLCHALEDPDPEVQATARYAFTKINRVGKIPESQIFTDMNTEEQN

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Crispr_ID: NC_019771_23

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019771_23

6056148-6056248

Orphan

A:N

Consensus_repeat	Method
AGATTCTTCCCTTCGGTCAGAATGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019771_23

>merge|NC_019771|23|6056148-6056248|CRISPRCasFinder
AGATTCTTCCCTTCGGTCAGAATGACACATCACATTCATGTTCTAGTTTTTCAACATCTTCTGAAATGATAAATTAAGATTCTTCCCTTTGGTCAGAATGA

>NC_019771|23|23|6056148-6056248|CRISPRCasFinder
AGATTCTTCCCTTCGGTCAGAATGA	CACATCACATTCATGTTCTAGTTTTTCAACATCTTCTGAAATGATAAATTA
AGATTCTTCCCTTTGGTCAGAATGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_019771.1\|WP_015217281.1\|6063922_6064732_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NC_019771.1\|WP_015217267.1\|6048291_6048666_-\|cytochrome-c	unknown	unknown	gnl\|CDD\|224921
NC_019771.1\|WP_015217271.1\|6050377_6050938_+\|adenosine-deaminase	unknown	unknown	gnl\|CDD\|238279
NC_019771.1\|WP_015217265.1\|6039634_6040933_-\|voltage-gated-chloride-channel-family-protein	unknown	unknown	gnl\|CDD\|239654
NC_019771.1\|WP_015217272.1\|6050977_6052336_+\|DUF3370-domain-containing-protein	unknown	unknown	gnl\|CDD\|314680
NC_019771.1\|WP_015217273.1\|6052568_6053162_-\|protoporphyrinogen-oxidase-HemJ	unknown	unknown	gnl\|CDD\|273223
NC_019771.1\|WP_015217278.1\|6060049_6060628_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
NC_019771.1\|WP_015217280.1\|6062352_6063756_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237171
NC_019771.1\|WP_015217283.1\|6066212_6066713_+\|TM2-domain-containing-protein	unknown	unknown	gnl\|CDD\|222840
NC_019771.1\|WP_015217269.1\|6049058_6049619_-\|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	unknown	unknown	gnl\|CDD\|223813
NC_019771.1\|WP_015217268.1\|6048875_6048989_+\|cytochrome-b6-f-complex-subunit-PetG	unknown	unknown	gnl\|CDD\|179084
NC_019771.1\|WP_015217270.1\|6049673_6050309_-\|imidazole-glycerol-phosphate-synthase-subunit-HisH	unknown	unknown	gnl\|CDD\|237288
NC_019771.1\|WP_015217282.1\|6064824_6065901_-\|magnesium-protoporphyrin-IX-monomethyl-ester-(oxidative)-cyclase	unknown	unknown	gnl\|CDD\|237458
NC_019771.1\|WP_015217279.1\|6061127_6062252_+\|site-2-protease-family-protein	unknown	unknown	gnl\|CDD\|100085
NC_019771.1\|WP_042465475.1\|6047531_6048002_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NC_019771.1\|WP_015217275.1\|6057779_6058607_+\|D-alanyl-D-alanine-carboxypeptidase-family-protein	unknown	unknown	gnl\|CDD\|367124
NC_019771.1\|WP_015212319.1\|6054530_6055751_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NC_019771.1\|WP_042466222.1\|6059176_6059752_+\|TIGR04376-family-protein	unknown	unknown	gnl\|CDD\|275169
NC_019771.1\|WP_015217276.1\|6058646_6058841_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|224514
NC_019771.1\|WP_015217274.1\|6056274_6057126_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|178633

Protein	Function_ID	Function_description	E-value
NC_019771.1\|WP_015217281.1\|6063922_6064732_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	9.76906e-16
NC_019771.1\|WP_015217267.1\|6048291_6048666_-\|cytochrome-c	gnl\|CDD\|224921	COG2010, CccA, Cytochrome c, mono- and diheme variants [Energy production and conversion].	1.90441e-08
NC_019771.1\|WP_015217271.1\|6050377_6050938_+\|adenosine-deaminase	gnl\|CDD\|238279	cd00501, Peptidase_C15, Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from proteolysis by other proteases until the pGlu is removed by a PGP. PGPs are cysteine proteases with a Cys-His-Glu/Asp catalytic triad. Type I PGPs are found in a wide variety of prokaryotes and eukaryotes. It is not clear whether the functional form is a monomer, a homodimer, or a homotetramer.	3.24526e-20
NC_019771.1\|WP_015217265.1\|6039634_6040933_-\|voltage-gated-chloride-channel-family-protein	gnl\|CDD\|239654	cd03682, ClC_sycA_like, ClC sycA-like chloride channel proteins. This ClC family presents in bacteria, where it facilitates acid resistance in acidic soil. Mutation of this gene (sycA) in Rhizobium tropici CIAT899 causes serious deficiencies in nodule development, nodulation competitiveness, and N2 fixation on Phaseolus vulgaris plants, due to its reduced ability for acid resistance. This family is part of the ClC chloride channel superfamiy. These proteins catalyse the selective flow of Cl- ions across cell membranes and Cl-/H+ exchange transport. These proteins share two characteristics that are apparently inherent to the entire ClC chloride channel superfamily: a unique double-barreled architecture and voltage-dependent gating mechanism. The gating is conferred by the permeating anion itself, acting as the gating charge.	2.00147e-171
NC_019771.1\|WP_015217272.1\|6050977_6052336_+\|DUF3370-domain-containing-protein	gnl\|CDD\|314680	pfam11850, DUF3370, Protein of unknown function (DUF3370). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 452 to 532 amino acids in length.	0
NC_019771.1\|WP_015217273.1\|6052568_6053162_-\|protoporphyrinogen-oxidase-HemJ	gnl\|CDD\|273223	TIGR00701, UPF0093_membrane_protein_HP_1484, TIGR00701 family protein. It appears this conserved hypothetical integral membrane protein is found only in gram negative bacteria. Completed genomes that include a member of this family include Rickettsia prowazekii, Synechocystis sp. PCC6803, and Helicobacter pylori. These proteins have 3 (Helicobacter pylori) to 5 (Synechocystis sp. PCC 6803) GES predicted transmembrane regions. Most members have 4 GES predicted transmembrane regions. [Hypothetical proteins, Conserved].	4.95805e-59
NC_019771.1\|WP_015217278.1\|6060049_6060628_+\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	9.08038e-38
NC_019771.1\|WP_015217280.1\|6062352_6063756_-\|hypothetical-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	0.00941659
NC_019771.1\|WP_015217283.1\|6066212_6066713_+\|TM2-domain-containing-protein	gnl\|CDD\|222840	PHA01886, PHA01886, TM2 domain-containing protein.	1.65025e-11
NC_019771.1\|WP_015217269.1\|6049058_6049619_-\|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	gnl\|CDD\|223813	COG0742, COG0742, N6-adenine-specific methylase [DNA replication, recombination, and repair].	1.51047e-66
NC_019771.1\|WP_015217268.1\|6048875_6048989_+\|cytochrome-b6-f-complex-subunit-PetG	gnl\|CDD\|179084	PRK00665, petG, cytochrome b6-f complex subunit PetG; Reviewed.	1.09542e-15
NC_019771.1\|WP_015217270.1\|6049673_6050309_-\|imidazole-glycerol-phosphate-synthase-subunit-HisH	gnl\|CDD\|237288	PRK13141, hisH, imidazole glycerol phosphate synthase subunit HisH; Provisional.	4.17869e-128
NC_019771.1\|WP_015217282.1\|6064824_6065901_-\|magnesium-protoporphyrin-IX-monomethyl-ester-(oxidative)-cyclase	gnl\|CDD\|237458	PRK13654, PRK13654, magnesium-protoporphyrin IX monomethyl ester cyclase; Provisional.	0
NC_019771.1\|WP_015217279.1\|6061127_6062252_+\|site-2-protease-family-protein	gnl\|CDD\|100085	cd06164, S2P-M50_SpoIVFB_CBS, SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation. In this subgroup, SpoIVFB (sporulation protein, stage IV cell wall formation, F locus, promoter-distal B) contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain. SpoIVFB is one of 4 proteins involved in endospore formation; the others are SpoIVFA (sporulation protein, stage IV cell wall formation, F locus, promoter-proximal A), BofA (bypass-of-forespore A), and SpoIVB (sporulation protein, stage IV cell wall formation, B locus). SpoIVFB is negatively regulated by SpoIVFA and BofA and activated by SpoIVB. It is thought that SpoIVFB, SpoIVFA, and BofA are located in the mother-cell membrane that surrounds the forespore and that SpoIVB is secreted from the forespore into the space between the two where it activates SpoIVFB. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown.	1.07573e-80
NC_019771.1\|WP_042465475.1\|6047531_6048002_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	7.90453e-18
NC_019771.1\|WP_015217275.1\|6057779_6058607_+\|D-alanyl-D-alanine-carboxypeptidase-family-protein	gnl\|CDD\|367124	pfam02557, VanY, D-alanyl-D-alanine carboxypeptidase.	4.20097e-12
NC_019771.1\|WP_015212319.1\|6054530_6055751_+\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.27075e-100
NC_019771.1\|WP_042466222.1\|6059176_6059752_+\|TIGR04376-family-protein	gnl\|CDD\|275169	TIGR04376, conserved_hypothetical_protein, TIGR04376 family protein. Members of this protein family resemble TIGR04375 and, more distantly, to phage shock protein A (PspA). Members are restricted to the Cyanobacteria.	2.93529e-80
NC_019771.1\|WP_015217276.1\|6058646_6058841_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	6.77499e-08
NC_019771.1\|WP_015217274.1\|6056274_6057126_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|178633	PLN03084, PLN03084, alpha/beta hydrolase fold protein; Provisional.	3.68636e-55

>NC_019771.1|WP_015212319.1|6054530_6055751_+|ISL3-family-transposase
MKFSVDQILNLPEMKVLDFQELVGAGIIITIEKAVNYSTCPDCEKTTYSIHQNHWRLIHDLSWSEKPVLLRINRRQFKCNKCKKVFSEKLNFVDKSKGYTKRLAIDIVAQVLDSNIHSVAERNDLSDEEVESMLKAQVSQILNINLNQVKRLGIDEIALVKGQGSYLAVLVDLDTRKPIELVKSRRIEEIREVIVKWGSQVLEQIVEVSMDLWSPYKSLVEELMPNANITADRFHVMKQVNDELDAMRKSEKRAAMSLDNKSERDRILAGLNKSKYSLIKNEDSLNEQQKERLNNVQKVSPILAKMHALKEEFRDIFESTKSWGESIMNLLDWMHDGLSYFPKSIGTMIRWFGEVVGYFDGRTTSGTVEGINNKLKLIKRLGYGFRNFSNFRLRSLLNWHFSINSP
>NC_019771.1|WP_015217273.1|6052568_6053162_-|protoporphyrinogen-oxidase-HemJ
MAYSWFKAFHIIGFVVWFAGLFYLVRLFIYHVEANQEPEPAKTILKNQYQIMEKRLYHIITVPGMIVTVAMAIGILSTNPDLLKETWLHLKLGFVGILLIYHHYCGRLMKQLAADECKWSGQHLRALNEAPTLLLVVIVMLAIFKNNLPTDITAWLIFGLVIFMAVSIQMYAKIRRRNKEKMIAEMNQVNQVPQTQS
>NC_019771.1|WP_015217272.1|6050977_6052336_+|DUF3370-domain-containing-protein
MLPLLFGLTLAQATPATPPPEEVVQPQEVRPLPGQLDNVPVFNSNSPELVLKEGILLSTFPVNGKKVPTAHLNFPFRGRFDIFAHHVAKAEPPENLRSLYLGIMLHNPGSQEVKVSILQGASYLSQPDAPFIQLNSFIPNNSGTVFAGPGSRVMSDVLRGRRQAIFPAQIVIPPGKSQMLLNLPIPVAELTPPINGRSTFMRLWSNGTVYAASLAMFAPTNADGSERAPNLAEWQNILDNGELSTPRDKTPTPLEETGKPRIYGRVAGVASGSQWRSLLVDNPTTKYLTIPQAGQAFSYALSTLHGGTFGTGQIQSAPMSVRYPDTAYRAHGNYGIQYSLRLPLLNNTQTQQKVSISLQTPLKEDQLTKSGLRFFTTPARQVFFRGTVRVRYQDEQGKRKTEFVHLVQTRGQAGEPLVSLNMKAGDSSLVEVDFLYPPDASPPQVLTVSTQK
>NC_019771.1|WP_015217271.1|6050377_6050938_+|adenosine-deaminase
MQKKILLTSFDTWLSEQQSNSSDDLLLELAKMACVSHDLNFLRRLPVNVQLASSRVIAKINELKPDYVICCGMAASRKQLSIEVLARILSLQSTDISSLDCAESFWQTTLQTTVNVEQLVDGTEVEISYDCGKFVCESLYYSVLDYVSQSQIPIPCIFVHVPILNQENLHSMIANFVLILNKLALV
>NC_019771.1|WP_015217270.1|6049673_6050309_-|imidazole-glycerol-phosphate-synthase-subunit-HisH
MPVIAVVDYDMGNLHSVCKGLEKAGATPKVTYSAKELEQADAIVLPGVGAFDPAVQHLRSRGLEQPIKDVIASGKPFLGICLGLQILFESSEEGTQPGLGIVRGKVRRFRSEAGITIPHMGWNQLQLTQSKSILWEHLPSQPWVYFVHSYYVDPTEPQVRAATVTHGSQTITAAIAHENLMAVQFHPEKSSNIGLQVLSNFVAQVREKIPA
>NC_019771.1|WP_015217269.1|6049058_6049619_-|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD
MSLRIYGNRLLKTLPGQETRPTSARVREAVFNIWQGKIDGCCWLDLCAGSGSMGAEALCRGASLVIGIEQSSRACTIIQQNWQQVAHNEQKFQILRGNILQQLKKLSGQKFDRIYFDPPYASGLYEPVLRAIADYQLLEPYGEIAVEHKPKNFTPPEILNWEICHHKVYGNTALTFYSTVALEQVE
>NC_019771.1|WP_015217268.1|6048875_6048989_+|cytochrome-b6-f-complex-subunit-PetG
MVEPLLSGIVLGLIFVTLSGLFYAAYKQYKRPNELGG
>NC_019771.1|WP_015217267.1|6048291_6048666_-|cytochrome-c
MDNQLTKPETLIQWIALSALAVLIAIPFTLLGVHIAQGSDPYIKNVVSLTGNPVQGKAIFQINCSGCHGLAADGLVGPSLQAVSKRKSRYGLIHQVISGDTPPMPKFQPSVQEMADLLSYLENL
>NC_019771.1|WP_042465475.1|6047531_6048002_+|tetratricopeptide-repeat-protein
MDSLSINSLLEDLKNSDANVRKQATRQIWRFWFQQKGVYGLEKIDHSQRLIDAGQLASAEELLTRLIQAQPDFAEAWNRRAFLYYSMGHYPKSLVDCQMVIQLNPVHFGAIHGMGLCYAAQGKYSEAIQAFQKALKIQPYSLVNQKLILECTLKLS
>NC_019771.1|WP_015217265.1|6039634_6040933_-|voltage-gated-chloride-channel-family-protein
MKYLLQFEIFIASRHLIKWLPISFVIGILAGAVSAALLVSLEWATNWRQSHQWIIAFLPIGGFFSAWIYHCFGRNVEAGNNLLLEEIHNPKNIIPFRMAPLVLLGTDLTHLFGGSAGREGTALQMSASLADQLTKILHFKGVSRRILLMAGIGGGFASVFGTPLAGTVFGLEILAIGKIHYDALFPSLIAAIVGNQITLLFGLHHTAYRHAAIIPTMTIWMFISAIIAGAIFGIVARVFSQVTHKINYLFKAKISYPPFRTFIGGAMVAAIVGLSGTTKYIGLGIPTIVDAFQTQLPPWDFAAKLGMTALTLGAGFKGGEVTPLFFIGATLGNALSLFLSLPAPLLAGMGFVAVFAGAANTPLASILMGIELFGLESGVFIAIACVVSYLFSGHSGIYTAQRIALNKYSSANLESGLTVGTYKQTKNIPENE
>NC_019771.1|WP_015217274.1|6056274_6057126_-|alpha/beta-fold-hydrolase
MSIQEHKITVDSLEWYYREAEPIGRSDLLPVVLLHGIIAQSYSWRNILPALAAQGTRAIAPDWIGYGFSGKPEKRDFAYTPDAFITALAAFIQALELERFSLVVQGYLGSVGLQYALRNPEKIANIAILNTPVSTSAKLPWKIQQMGLPLAGEVMTQDPLLVDRTLEAGSRYRIEDKDLDIYRKPYLKSSSSGRGLLSTIRNLQLDQAMTEIETGFKQWQKPILLQWGMIDPWLSVDIAETFVQSVPDAEIIKLNNVGHYPQEHYHETILQDLLPFVRCSKPN
>NC_019771.1|WP_015217275.1|6057779_6058607_+|D-alanyl-D-alanine-carboxypeptidase-family-protein
MKHHSRIKRRLRKITFITVIIFLFFTLVGSTDTNYYQSLQNAALTINANIVPSTSAPFIPNQQLNEQERFLATITHQLANIPQIDSYEYILLRAYGAVFINQESEVKLPQKVILDDESETQNFQGSMRVALVEGTRECYLQKSAADAFNKARILANIPLKSGYSGDCTRSFATNLRFWQKYANSGTLEQVKQGKETKILDTVAPPGTSQHLWGLAIDLRVSSPLQRKVLNQNGWFQTVTNDIPHWTYLRWSEEDLPKFGLRAKIIRGITYWVTPI
>NC_019771.1|WP_015217276.1|6058646_6058841_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MRYQVKLNKIDKVYAIWCPALPGCWTVGETEQEALDKMKYAIQAYLETMDEVGKNAEFYYVEVR
>NC_019771.1|WP_042466222.1|6059176_6059752_+|TIGR04376-family-protein
MGLFDDLSRFLEERLEEFLRNNPHLELEMLLEQLREQEEDTLKLIAELQLQEKRSQDDILSTAQEIQRWHIRVQKAKAAGREDLAAPAQDREDALLREGNQRWGQMQGLKDRITQSQELLRKIQQRRQEVQAKATAAQTARQTERAKVQTPQRLETNAWQTSASSFDDLEDKFHRWETQDELEQMKRNMGK
>NC_019771.1|WP_015217278.1|6060049_6060628_+|ABC-transporter-permease
MENSILLDVLATLQRLFVGYIPASVLGIFIGFVIGINGIVYQLFTRLFQIPNSIPSIAFLPIALILFKENETAAIFVVFIGVLWAVIVETATGIQQFRKYDNNFRVAIHHIFKALRIGLWIAWFTVIATEMLAGSKGLGFLAWNGYKAGNPKYIIDSILYIAIIGVFLDQLLDLTGYILSQMVSDRGKSSKT
>NC_019771.1|WP_015217279.1|6061127_6062252_+|site-2-protease-family-protein
MNSTIRVGNLFGIPFYIHPSWFLVLGLVTWSYSSGLAAQFPQLGGGLPLVLGLMTALLLFGSVVAHELGHSFVAIRQGIDVKSITLFIFGGLASLEKESQTPGEAFWVAIAGPLVSFLLFATATTVGFATAASGPLAAILGLLASVNLTLALFNLIPGLPLDGGNILKAIVWKITGKSYKGVVVASRIGQIFGWIAIASGLIPLLLFGSFVNVWNLLIGSFLLQNAGKAAQFARVQEKLTGLTAADAVNNDSPIVTANLTLREFADQQLLNAQEYRRFLVTDEEGQLLGAISIDDLRTIPNTLWSDTQVFQVMKPIEQSSTVQSDQPLLEVVQLLETQKLSALAVIRENGFLVGILEKAAIINLLQKKVQTKFA
>NC_019771.1|WP_015217280.1|6062352_6063756_-|hypothetical-protein
MHKTFKSKLLLLLTFCLFNSFLPASASVLCSADSSEQDYKIANRYDRDGDRGSNGRSGRDGRSGENQTISANGSPVNIDLSGKDGEDGEDGERGSRPRCRDQRENVENSINAPDGGHGGAGGKGGDGGHGGSLTVYYTNLADLQKIFVRAVGGEGGRGRQGGRGTAGCNCNRRSWEVKTCKGTPGSPDYKCTSKVYRCSNGSDGRDGSYGQNGKPGRLGTLSIINSNKPLADDAPTLKLALSELANKEFNLSKNKWQQRQGATSLLAVGSVIADEYREFEKRLEGTFKLIWQDKQPITSFANQAVTLSLNDSEKVEIAFADDLWVDGSANMQGKLTEFTVNYAIPKQDVTRLAVAEFADVGQKLNLKIVDLASRSDLINTQFRVKYRARDNFSGSSNYQTFYEGEIPNELVTRSYNRFTLDLGKLKIPSDALNSGVNVDIEVVAIRSLGGRSAQQTLNWQGAIRKVK
>NC_019771.1|WP_015217281.1|6063922_6064732_-|tetratricopeptide-repeat-protein
MLNSIYAYGYSSLAYILYNSGDYQGAIENYSQAILLNSEDLTSYISRGVARSLTKDYQNAIEDFNQAIRLSPQYAQAYAERGIARAAIGENQTAIEDCHRAIQLNPQYVRAYFGRGAAHFYSGNYQGALEDFSLITRMERSAISYYNLGILQYSQGINSQVIKHLTKALDIDPNLMSAYYVRGNACYDLGDEQGAFADFAEAKHIESVGADKIYFEDEFALYARGLAYHRLGNRENAIADLQESAQIALKHQNTIFHQKVINFMSEIQS
>NC_019771.1|WP_015217282.1|6064824_6065901_-|magnesium-protoporphyrin-IX-monomethyl-ester-(oxidative)-cyclase
MVDSLKKPGFEEMRPGVKVPSKESLLTPRFYTTDFDEMARMDISVNEDELRAILEEFRIDYNRHHFVRDGEFEQSWDHIDGETRQLFVEFLERSCTAEFSGFLLYKELGRRLKDKSPLLAECFNLMSRDEARHAGFLNKAMSDFNLSLDLGFLTKSRSYTFFKPKFIFYATYLSEKIGYWRYITIYRHLEQHPEDRIYPIFRFFENWCQDENRHGDFFDAVMRAQPQMLNDWRAKLWSRFFLLSVFATMYLNDIQRKDFYASLGLDAREYDIHVIKKTNETAGRVFPLMLDVENPEFYQRLDVCVKNNEKLTAISNSNTPKFLQFFQKAPIYLSHGWQLLNLYLMKPIDAVSAHGQAR
>NC_019771.1|WP_015217283.1|6066212_6066713_+|TM2-domain-containing-protein
MNAQENRNKDRLLISYALCAGGFLGIAGLHRLYNGKIATGVLWLLTFGFFYVGQLVDLVLIPGMVDEYEQKLRLKAGLSPLGLPLNQAVVNSQVYRPTGNQLMVQLLEAAEIKGGNLTVTQGVKATGASFAEVEKVLTEMLQSGYVRIDNDPITGAVTYHFYELSS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_019771_8	8.1\|1822433\|27\|NC_019771\|CRISPRCasFinder	1822433-1822459	27	NZ_CP026123	Aeromonas sp. ASNIH5 plasmid pKPC-b21f, complete sequence	18454-18480	4	0.852
NC_019771_8	8.1\|1822433\|27\|NC_019771\|CRISPRCasFinder	1822433-1822459	27	NZ_CP026408	Aeromonas sp. ASNIH2 plasmid pAER-f133, complete sequence	3994-4020	4	0.852
NC_019771_8	8.1\|1822433\|27\|NC_019771\|CRISPRCasFinder	1822433-1822459	27	NZ_CP009332	Bacillus thuringiensis strain HD1011 plasmid 3, complete sequence	69526-69552	4	0.852
NC_019771_8	8.1\|1822433\|27\|NC_019771\|CRISPRCasFinder	1822433-1822459	27	NZ_CP053977	Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed1, complete sequence	43240-43266	4	0.852
NC_019771_8	8.1\|1822433\|27\|NC_019771\|CRISPRCasFinder	1822433-1822459	27	DQ222855	Bacillus anthracis phage Gamma isolate 53, complete genome	18145-18171	4	0.852
NC_019771_8	8.1\|1822433\|27\|NC_019771\|CRISPRCasFinder	1822433-1822459	27	DQ289555	Bacillus anthracis phage W Beta, complete genome	18274-18300	4	0.852
NC_019771_8	8.1\|1822433\|27\|NC_019771\|CRISPRCasFinder	1822433-1822459	27	NC_007814	Bacillus phage Fah, complete genome	18136-18162	4	0.852
NC_019771_8	8.1\|1822433\|27\|NC_019771\|CRISPRCasFinder	1822433-1822459	27	DQ150593	Bacillus anthracis bacteriophage Fah, complete sequence	18136-18162	4	0.852
NC_019771_8	8.1\|1822433\|27\|NC_019771\|CRISPRCasFinder	1822433-1822459	27	DQ222853	Bacillus anthracis phage Gamma isolate 51, complete genome	18145-18171	4	0.852
NC_019771_8	8.1\|1822433\|27\|NC_019771\|CRISPRCasFinder	1822433-1822459	27	MK085976	Bacillus phage AP631, complete genome	18258-18284	4	0.852
NC_019771_8	8.1\|1822433\|27\|NC_019771\|CRISPRCasFinder	1822433-1822459	27	DQ221100	Bacteriophage gamma putative terminase small subunit, putative terminase large subunit, putative portal protein, putative prohead protease, putative phage structural protein, putative DNA packaging protein, putative head-tail adaptor, phage related proteins, putative major tail protein, phage related protein, putative tail tape measure protein, phage related protein, putative minor structural protein, putative holin, N-acetylmuramoyl-L-alanine amidase (PlyG), putative lipoprotein, putative transcriptional regulator, conserved hypothetical proteins, FtsK/SpoIIIE family protein, phage related protein, conserved hypothetical protein, putative transcriptional regulator, putative site-specific recombinase, conserved hypothetical protein, putative transcriptional regulators, putative antirepressor, conserved hypothetical protein, putative DNA replication proteins, conserved hypothetical protein, phage related proteins, conserved hypothetical protein, putative transglycosylase, and putative endonuclease genes, complete cds	18145-18171	4	0.852
NC_019771_8	8.1\|1822433\|27\|NC_019771\|CRISPRCasFinder	1822433-1822459	27	DQ222851	Bacillus anthracis phage Cherry, complete genome	18145-18171	4	0.852
NC_019771_8	8.1\|1822433\|27\|NC_019771\|CRISPRCasFinder	1822433-1822459	27	DQ289556	Bacillus anthracis phage Gamma isolate d'Herelle, complete genome	18274-18300	4	0.852
NC_019771_8	8.1\|1822433\|27\|NC_019771\|CRISPRCasFinder	1822433-1822459	27	NC_007734	Bacillus phage WBeta, complete genome	18274-18300	4	0.852
NC_019771_8	8.1\|1822433\|27\|NC_019771\|CRISPRCasFinder	1822433-1822459	27	NC_007458	Bacillus phage Gamma, complete genome	18145-18171	4	0.852
NC_019771_7	7.13\|1762670\|33\|NC_019771\|CRISPRCasFinder,CRT	1762670-1762702	33	MN694597	Marine virus AFVG_250M99, complete genome	10522-10554	7	0.788
NC_019771_7	7.36\|1762672\|33\|NC_019771\|PILER-CR	1762672-1762704	33	MN694597	Marine virus AFVG_250M99, complete genome	10522-10554	7	0.788
NC_019771_1	1.8\|58219\|33\|NC_019771\|PILER-CR,CRISPRCasFinder,CRT	58219-58251	33	AP022644	Bacillus wiedmannii PL1 plasmid pBwiPL1-1 DNA, complete sequence	346160-346192	8	0.758
NC_019771_1	1.8\|58219\|33\|NC_019771\|PILER-CR,CRISPRCasFinder,CRT	58219-58251	33	NZ_CP029455	Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence	307786-307818	8	0.758
NC_019771_13	13.7\|3251031\|34\|NC_019771\|PILER-CR,CRISPRCasFinder,CRT	3251031-3251064	34	MN856100	Bacteriophage sp. isolate 2, complete genome	133377-133410	8	0.765
NC_019771_16	16.1\|4076962\|34\|NC_019771\|CRISPRCasFinder	4076962-4076995	34	NC_019429	Anabaena sp. 90 plasmid pANA02, complete sequence	10154-10187	8	0.765
NC_019771_18	18.27\|4754348\|37\|NC_019771\|CRISPRCasFinder,CRT,PILER-CR	4754348-4754384	37	MT773554	Myoviridae sp. isolate BML_2 genomic sequence	8813-8849	8	0.784
NC_019771_19	19.16\|5002162\|33\|NC_019771\|PILER-CR,CRISPRCasFinder,CRT	5002162-5002194	33	NZ_CP022288	Bacillus subtilis strain SX01705 plasmid pSX01705-1, complete sequence	28350-28382	8	0.758
NC_019771_19	19.16\|5002162\|33\|NC_019771\|PILER-CR,CRISPRCasFinder,CRT	5002162-5002194	33	NZ_CP035229	Bacillus licheniformis strain SRCM103529 plasmid unnamed1, complete sequence	73004-73036	8	0.758
NC_019771_21	21.16\|5739743\|35\|NC_019771\|PILER-CR,CRISPRCasFinder,CRT	5739743-5739777	35	NC_048775	Aeromonas phage LAh_8, complete genome	34463-34497	8	0.771
NC_019771_21	21.20\|5740031\|34\|NC_019771\|PILER-CR,CRISPRCasFinder,CRT	5740031-5740064	34	NZ_CP045274	Bacillus megaterium strain FDU301 plasmid pFDU301B, complete sequence	20795-20828	8	0.765
NC_019771_21	21.27\|5740538\|33\|NC_019771\|PILER-CR,CRISPRCasFinder,CRT	5740538-5740570	33	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	17148-17180	8	0.758
NC_019771_1	1.12\|58505\|35\|NC_019771\|CRISPRCasFinder,CRT	58505-58539	35	MG592505	Vibrio phage 1.134.O._10N.222.52.B8, partial genome	33790-33824	9	0.743
NC_019771_1	1.12\|58505\|35\|NC_019771\|CRISPRCasFinder,CRT	58505-58539	35	MG592457	Vibrio phage 1.082.O._10N.261.49.E4, partial genome	34131-34165	9	0.743
NC_019771_1	1.12\|58505\|35\|NC_019771\|CRISPRCasFinder,CRT	58505-58539	35	MG592557	Vibrio phage 1.189.B._10N.286.51.B5, partial genome	33897-33931	9	0.743
NC_019771_1	1.12\|58505\|35\|NC_019771\|CRISPRCasFinder,CRT	58505-58539	35	MG592559	Vibrio phage 1.189.O._10N.286.51.B5, partial genome	33896-33930	9	0.743
NC_019771_1	1.12\|58505\|35\|NC_019771\|CRISPRCasFinder,CRT	58505-58539	35	MG592490	Vibrio phage 1.116.O._10N.222.52.C10, partial genome	33468-33502	9	0.743
NC_019771_1	1.12\|58505\|35\|NC_019771\|CRISPRCasFinder,CRT	58505-58539	35	MG592558	Vibrio phage 1.189.C._10N.286.51.B5, partial genome	33897-33931	9	0.743
NC_019771_1	1.12\|58505\|35\|NC_019771\|CRISPRCasFinder,CRT	58505-58539	35	MG592539	Vibrio phage 1.172.O._10N.261.52.F5, partial genome	33469-33503	9	0.743
NC_019771_7	7.3\|1761935\|34\|NC_019771\|CRISPRCasFinder,CRT	1761935-1761968	34	NC_004688	Mycobacterium phage Omega, complete genome	83536-83569	9	0.735
NC_019771_7	7.3\|1761935\|34\|NC_019771\|CRISPRCasFinder,CRT	1761935-1761968	34	AY129338	Mycobacterium virus Omega, complete genome	83536-83569	9	0.735
NC_019771_7	7.26\|1761937\|34\|NC_019771\|PILER-CR	1761937-1761970	34	NC_004688	Mycobacterium phage Omega, complete genome	83536-83569	9	0.735
NC_019771_7	7.26\|1761937\|34\|NC_019771\|PILER-CR	1761937-1761970	34	AY129338	Mycobacterium virus Omega, complete genome	83536-83569	9	0.735
NC_019771_19	19.14\|5002019\|35\|NC_019771\|PILER-CR,CRISPRCasFinder,CRT	5002019-5002053	35	NZ_CP029092	Pseudomonas aeruginosa strain AR441 plasmid unnamed2, complete sequence	156-190	9	0.743
NC_019771_19	19.14\|5002019\|35\|NC_019771\|PILER-CR,CRISPRCasFinder,CRT	5002019-5002053	35	NZ_CP027168	Pseudomonas aeruginosa strain AR_0356 plasmid unnamed1, complete sequence	28651-28685	9	0.743
NC_019771_21	21.27\|5740538\|33\|NC_019771\|PILER-CR,CRISPRCasFinder,CRT	5740538-5740570	33	NC_025440	Listeria phage WIL-1, complete genome	42164-42196	9	0.727
NC_019771_21	21.27\|5740538\|33\|NC_019771\|PILER-CR,CRISPRCasFinder,CRT	5740538-5740570	33	KJ535721	Listeria phage List-36, complete genome	3246-3278	9	0.727
NC_019771_17	17.1\|4112670\|45\|NC_019771\|CRISPRCasFinder	4112670-4112714	45	NZ_CP051207	Dolichospermum flos-aquae CCAP 1403/13F plasmid pAfl69, complete sequence	35055-35099	10	0.778
NC_019771_21	21.15\|5739672\|34\|NC_019771\|PILER-CR,CRISPRCasFinder,CRT	5739672-5739705	34	MK416013	Klebsiella phage ST16-OXA48phi5.1, complete genome	48730-48763	10	0.706
NC_019771_19	19.14\|5002019\|35\|NC_019771\|PILER-CR,CRISPRCasFinder,CRT	5002019-5002053	35	MN961669	Pseudomonas monteilii strain 918607 plasmid p918607-IMP, complete sequence	21687-21721	11	0.686
NC_019771_21	21.27\|5740538\|33\|NC_019771\|PILER-CR,CRISPRCasFinder,CRT	5740538-5740570	33	NZ_CP020558	Paenibacillus larvae subsp. pulvifaciens strain SAG 10367 plasmid pPLP3, complete sequence	23380-23412	11	0.667

1. spacer 8.1|1822433|27|NC_019771|CRISPRCasFinder matches to NZ_CP026123 (Aeromonas sp. ASNIH5 plasmid pKPC-b21f, complete sequence) position: , mismatch: 4, identity: 0.852

ccacaacacaaaaaatcatccaatcac	CRISPR spacer
ccacaacccaaaaaatcatccaacaaa	Protospacer
******* ***************. *

2. spacer 8.1|1822433|27|NC_019771|CRISPRCasFinder matches to NZ_CP026408 (Aeromonas sp. ASNIH2 plasmid pAER-f133, complete sequence) position: , mismatch: 4, identity: 0.852

ccacaacacaaaaaatcatccaatcac	CRISPR spacer
ccacaacccaaaaaatcatccaacaaa	Protospacer
******* ***************. *

3. spacer 8.1|1822433|27|NC_019771|CRISPRCasFinder matches to NZ_CP009332 (Bacillus thuringiensis strain HD1011 plasmid 3, complete sequence) position: , mismatch: 4, identity: 0.852

ccacaacacaaaaaatcatccaatcac	CRISPR spacer
caacaaaacaaaacatcatccaatcag	Protospacer
* **** ****** ************

4. spacer 8.1|1822433|27|NC_019771|CRISPRCasFinder matches to NZ_CP053977 (Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.852

ccacaacacaaaaaatcatccaatcac	CRISPR spacer
caacaaaacaaaacatcatccaatcag	Protospacer
* **** ****** ************

5. spacer 8.1|1822433|27|NC_019771|CRISPRCasFinder matches to DQ222855 (Bacillus anthracis phage Gamma isolate 53, complete genome) position: , mismatch: 4, identity: 0.852

ccacaacacaaaaaatcatccaatcac	CRISPR spacer
caacaaaacaaaacatcatccaatcag	Protospacer
* **** ****** ************

6. spacer 8.1|1822433|27|NC_019771|CRISPRCasFinder matches to DQ289555 (Bacillus anthracis phage W Beta, complete genome) position: , mismatch: 4, identity: 0.852

ccacaacacaaaaaatcatccaatcac	CRISPR spacer
caacaaaacaaaacatcatccaatcag	Protospacer
* **** ****** ************

7. spacer 8.1|1822433|27|NC_019771|CRISPRCasFinder matches to NC_007814 (Bacillus phage Fah, complete genome) position: , mismatch: 4, identity: 0.852

ccacaacacaaaaaatcatccaatcac	CRISPR spacer
caacaaaacaaaacatcatccaatcag	Protospacer
* **** ****** ************

8. spacer 8.1|1822433|27|NC_019771|CRISPRCasFinder matches to DQ150593 (Bacillus anthracis bacteriophage Fah, complete sequence) position: , mismatch: 4, identity: 0.852

ccacaacacaaaaaatcatccaatcac	CRISPR spacer
caacaaaacaaaacatcatccaatcag	Protospacer
* **** ****** ************

9. spacer 8.1|1822433|27|NC_019771|CRISPRCasFinder matches to DQ222853 (Bacillus anthracis phage Gamma isolate 51, complete genome) position: , mismatch: 4, identity: 0.852

ccacaacacaaaaaatcatccaatcac	CRISPR spacer
caacaaaacaaaacatcatccaatcag	Protospacer
* **** ****** ************

10. spacer 8.1|1822433|27|NC_019771|CRISPRCasFinder matches to MK085976 (Bacillus phage AP631, complete genome) position: , mismatch: 4, identity: 0.852

ccacaacacaaaaaatcatccaatcac	CRISPR spacer
caacaaaacaaaacatcatccaatcag	Protospacer
* **** ****** ************

11. spacer 8.1|1822433|27|NC_019771|CRISPRCasFinder matches to DQ221100 (Bacteriophage gamma putative terminase small subunit, putative terminase large subunit, putative portal protein, putative prohead protease, putative phage structural protein, putative DNA packaging protein, putative head-tail adaptor, phage related proteins, putative major tail protein, phage related protein, putative tail tape measure protein, phage related protein, putative minor structural protein, putative holin, N-acetylmuramoyl-L-alanine amidase (PlyG), putative lipoprotein, putative transcriptional regulator, conserved hypothetical proteins, FtsK/SpoIIIE family protein, phage related protein, conserved hypothetical protein, putative transcriptional regulator, putative site-specific recombinase, conserved hypothetical protein, putative transcriptional regulators, putative antirepressor, conserved hypothetical protein, putative DNA replication proteins, conserved hypothetical protein, phage related proteins, conserved hypothetical protein, putative transglycosylase, and putative endonuclease genes, complete cds) position: , mismatch: 4, identity: 0.852

ccacaacacaaaaaatcatccaatcac	CRISPR spacer
caacaaaacaaaacatcatccaatcag	Protospacer
* **** ****** ************

12. spacer 8.1|1822433|27|NC_019771|CRISPRCasFinder matches to DQ222851 (Bacillus anthracis phage Cherry, complete genome) position: , mismatch: 4, identity: 0.852

ccacaacacaaaaaatcatccaatcac	CRISPR spacer
caacaaaacaaaacatcatccaatcag	Protospacer
* **** ****** ************

13. spacer 8.1|1822433|27|NC_019771|CRISPRCasFinder matches to DQ289556 (Bacillus anthracis phage Gamma isolate d'Herelle, complete genome) position: , mismatch: 4, identity: 0.852

ccacaacacaaaaaatcatccaatcac	CRISPR spacer
caacaaaacaaaacatcatccaatcag	Protospacer
* **** ****** ************

14. spacer 8.1|1822433|27|NC_019771|CRISPRCasFinder matches to NC_007734 (Bacillus phage WBeta, complete genome) position: , mismatch: 4, identity: 0.852

ccacaacacaaaaaatcatccaatcac	CRISPR spacer
caacaaaacaaaacatcatccaatcag	Protospacer
* **** ****** ************

15. spacer 8.1|1822433|27|NC_019771|CRISPRCasFinder matches to NC_007458 (Bacillus phage Gamma, complete genome) position: , mismatch: 4, identity: 0.852

ccacaacacaaaaaatcatccaatcac	CRISPR spacer
caacaaaacaaaacatcatccaatcag	Protospacer
* **** ****** ************

16. spacer 7.13|1762670|33|NC_019771|CRISPRCasFinder,CRT matches to MN694597 (Marine virus AFVG_250M99, complete genome) position: , mismatch: 7, identity: 0.788

ataaaataaaacctgtaactagtttagtcgaat	CRISPR spacer
caaaaataaaacctgtaaaaagtttagtccaga	Protospacer
  ****************  ********* *.

17. spacer 7.36|1762672|33|NC_019771|PILER-CR matches to MN694597 (Marine virus AFVG_250M99, complete genome) position: , mismatch: 7, identity: 0.788

ataaaataaaacctgtaactagtttagtcgaat	CRISPR spacer
caaaaataaaacctgtaaaaagtttagtccaga	Protospacer
  ****************  ********* *.

18. spacer 1.8|58219|33|NC_019771|PILER-CR,CRISPRCasFinder,CRT matches to AP022644 (Bacillus wiedmannii PL1 plasmid pBwiPL1-1 DNA, complete sequence) position: , mismatch: 8, identity: 0.758

atcaaggtaaagtacgattgttatcttatccat	CRISPR spacer
ttttataaaaagtacgattgttttgttatccat	Protospacer
 *. * . ************** * ********

19. spacer 1.8|58219|33|NC_019771|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029455 (Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence) position: , mismatch: 8, identity: 0.758

atcaaggtaaagtacgattgttatcttatccat	CRISPR spacer
ttttataaaaagtacgattgttttgttatccat	Protospacer
 *. * . ************** * ********

20. spacer 13.7|3251031|34|NC_019771|PILER-CR,CRISPRCasFinder,CRT matches to MN856100 (Bacteriophage sp. isolate 2, complete genome) position: , mismatch: 8, identity: 0.765

---cgttagcttctgggtcaaaagttaagtctttaac	CRISPR spacer
atacattg---tcaggctcaaaagttaagtctttacc	Protospacer
   *.**.   ** ** ****************** *

21. spacer 16.1|4076962|34|NC_019771|CRISPRCasFinder matches to NC_019429 (Anabaena sp. 90 plasmid pANA02, complete sequence) position: , mismatch: 8, identity: 0.765

taaatcctgagcatcctgattcagacaaaatgaa	CRISPR spacer
ttaatcctggacatcctgattcagacaagttact	Protospacer
* *******..*****************. *.

22. spacer 18.27|4754348|37|NC_019771|CRISPRCasFinder,CRT,PILER-CR matches to MT773554 (Myoviridae sp. isolate BML_2 genomic sequence) position: , mismatch: 8, identity: 0.784

cattctagaaagaaagattccataagagaagaaaaac	CRISPR spacer
cattctagaaagaaagattccaaaaggccatcataaa	Protospacer
********************** ***.  *  * **

23. spacer 19.16|5002162|33|NC_019771|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022288 (Bacillus subtilis strain SX01705 plasmid pSX01705-1, complete sequence) position: , mismatch: 8, identity: 0.758

agtccctcgtctgacaacttatctaaatttttc	CRISPR spacer
aattcctcgtctgacaacttttccaaataatcg	Protospacer
*.*.**************** **.****  *.

24. spacer 19.16|5002162|33|NC_019771|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035229 (Bacillus licheniformis strain SRCM103529 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

agtccctcgtctgacaacttatctaaatttttc	CRISPR spacer
aattcctcgtctgacaacttttccaaataatcg	Protospacer
*.*.**************** **.****  *.

25. spacer 21.16|5739743|35|NC_019771|PILER-CR,CRISPRCasFinder,CRT matches to NC_048775 (Aeromonas phage LAh_8, complete genome) position: , mismatch: 8, identity: 0.771

-tttacacacctgatacaaattgctttgcaaaaaag	CRISPR spacer
attcata-acctgacacaaattgctttgcataatgt	Protospacer
 **.*.* ******.*************** ** .

26. spacer 21.20|5740031|34|NC_019771|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045274 (Bacillus megaterium strain FDU301 plasmid pFDU301B, complete sequence) position: , mismatch: 8, identity: 0.765

gctacatggtttgttactcccaaaaagtcagata	CRISPR spacer
gcgtattggtttgttactcccaaaatgccagttc	Protospacer
**    ******************* *.*** *

27. spacer 21.27|5740538|33|NC_019771|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.758

gaaggaagtatttttacaaatatatttgctaca	CRISPR spacer
gcagtcggtatttttacaaaaatatttcctaac	Protospacer
* **  .************* ****** ***

28. spacer 1.12|58505|35|NC_019771|CRISPRCasFinder,CRT matches to MG592505 (Vibrio phage 1.134.O._10N.222.52.B8, partial genome) position: , mismatch: 9, identity: 0.743

acttagtttttcttgctctgaca---ttttagccccta	CRISPR spacer
tgttagcttttcttgctctgtcatttttttaatcc---	Protospacer
  ****.************* **   *****..**

29. spacer 1.12|58505|35|NC_019771|CRISPRCasFinder,CRT matches to MG592457 (Vibrio phage 1.082.O._10N.261.49.E4, partial genome) position: , mismatch: 9, identity: 0.743

acttagtttttcttgctctgacattttagccccta---	CRISPR spacer
tgttagtttctcttgctctgtcatttt---tcttaatc	Protospacer
  *******.********** ******   .*.**

30. spacer 1.12|58505|35|NC_019771|CRISPRCasFinder,CRT matches to MG592557 (Vibrio phage 1.189.B._10N.286.51.B5, partial genome) position: , mismatch: 9, identity: 0.743

acttagtttttcttgctctgaca---ttttagccccta	CRISPR spacer
tattagtttctcttgctctgtcatttttttaatcc---	Protospacer
  *******.********** **   *****..**

31. spacer 1.12|58505|35|NC_019771|CRISPRCasFinder,CRT matches to MG592559 (Vibrio phage 1.189.O._10N.286.51.B5, partial genome) position: , mismatch: 9, identity: 0.743

acttagtttttcttgctctgaca---ttttagccccta	CRISPR spacer
tattagtttctcttgctctgtcatttttttaatcc---	Protospacer
  *******.********** **   *****..**

32. spacer 1.12|58505|35|NC_019771|CRISPRCasFinder,CRT matches to MG592490 (Vibrio phage 1.116.O._10N.222.52.C10, partial genome) position: , mismatch: 9, identity: 0.743

acttagtttttcttgctctgaca---ttttagccccta	CRISPR spacer
tgttagcttttcttgctctgtcatttttttaatcc---	Protospacer
  ****.************* **   *****..**

33. spacer 1.12|58505|35|NC_019771|CRISPRCasFinder,CRT matches to MG592558 (Vibrio phage 1.189.C._10N.286.51.B5, partial genome) position: , mismatch: 9, identity: 0.743

acttagtttttcttgctctgaca---ttttagccccta	CRISPR spacer
tattagtttctcttgctctgtcatttttttaatcc---	Protospacer
  *******.********** **   *****..**

34. spacer 1.12|58505|35|NC_019771|CRISPRCasFinder,CRT matches to MG592539 (Vibrio phage 1.172.O._10N.261.52.F5, partial genome) position: , mismatch: 9, identity: 0.743

acttagtttttcttgctctgaca---ttttagccccta	CRISPR spacer
tgttagcttttcttgctctgtcatttttttaatcc---	Protospacer
  ****.************* **   *****..**

35. spacer 7.3|1761935|34|NC_019771|CRISPRCasFinder,CRT matches to NC_004688 (Mycobacterium phage Omega, complete genome) position: , mismatch: 9, identity: 0.735

agatttggtgaggagggtggtcgccttgcttgga	CRISPR spacer
atatacccagaggagggtggtcactttgcttggt	Protospacer
* ** .   *************.*.********

36. spacer 7.3|1761935|34|NC_019771|CRISPRCasFinder,CRT matches to AY129338 (Mycobacterium virus Omega, complete genome) position: , mismatch: 9, identity: 0.735

agatttggtgaggagggtggtcgccttgcttgga	CRISPR spacer
atatacccagaggagggtggtcactttgcttggt	Protospacer
* ** .   *************.*.********

37. spacer 7.26|1761937|34|NC_019771|PILER-CR matches to NC_004688 (Mycobacterium phage Omega, complete genome) position: , mismatch: 9, identity: 0.735

agatttggtgaggagggtggtcgccttgcttgga	CRISPR spacer
atatacccagaggagggtggtcactttgcttggt	Protospacer
* ** .   *************.*.********

38. spacer 7.26|1761937|34|NC_019771|PILER-CR matches to AY129338 (Mycobacterium virus Omega, complete genome) position: , mismatch: 9, identity: 0.735

agatttggtgaggagggtggtcgccttgcttgga	CRISPR spacer
atatacccagaggagggtggtcactttgcttggt	Protospacer
* ** .   *************.*.********

39. spacer 19.14|5002019|35|NC_019771|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029092 (Pseudomonas aeruginosa strain AR441 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.743

gttcggtctgttactgctgctggagttgttctaac	CRISPR spacer
tttcggtctgctcctgctgctggagtttcggcaaa	Protospacer
 *********.* ************** .  .**

40. spacer 19.14|5002019|35|NC_019771|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027168 (Pseudomonas aeruginosa strain AR_0356 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.743

gttcggtctgttactgctgctggagttgttctaac	CRISPR spacer
tttcggtctgctcctgctgctggagtttcggcaaa	Protospacer
 *********.* ************** .  .**

41. spacer 21.27|5740538|33|NC_019771|PILER-CR,CRISPRCasFinder,CRT matches to NC_025440 (Listeria phage WIL-1, complete genome) position: , mismatch: 9, identity: 0.727

gaaggaagtatttttacaaatatatttgctaca	CRISPR spacer
aatgtcccaatttttacaaatatattagcaaca	Protospacer
.* *     ***************** ** ***

42. spacer 21.27|5740538|33|NC_019771|PILER-CR,CRISPRCasFinder,CRT matches to KJ535721 (Listeria phage List-36, complete genome) position: , mismatch: 9, identity: 0.727

gaaggaagtatttttacaaatatatttgctaca	CRISPR spacer
aatgttccaatttttacaaatatattagcaaca	Protospacer
.* *     ***************** ** ***

43. spacer 17.1|4112670|45|NC_019771|CRISPRCasFinder matches to NZ_CP051207 (Dolichospermum flos-aquae CCAP 1403/13F plasmid pAfl69, complete sequence) position: , mismatch: 10, identity: 0.778

gtctgaatcaagatttccaggatttaaggattttcaggataatgc	CRISPR spacer
gtctgaatcaggatttccaggatttaaggatttaaggatttacag	Protospacer
**********.**********************  .*. * *..

44. spacer 21.15|5739672|34|NC_019771|PILER-CR,CRISPRCasFinder,CRT matches to MK416013 (Klebsiella phage ST16-OXA48phi5.1, complete genome) position: , mismatch: 10, identity: 0.706

tttaatattaaataccccagaattttcataccaa	CRISPR spacer
gctccaattatgtaccccagaattttcatatccc	Protospacer
 .*   **** .******************.*

45. spacer 19.14|5002019|35|NC_019771|PILER-CR,CRISPRCasFinder,CRT matches to MN961669 (Pseudomonas monteilii strain 918607 plasmid p918607-IMP, complete sequence) position: , mismatch: 11, identity: 0.686

gttcggtctgttactgctgctggagttgttctaac	CRISPR spacer
tttcggcctgttcctgctgctggagtttcggcgca	Protospacer
 *****.***** ************** .  ..

46. spacer 21.27|5740538|33|NC_019771|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020558 (Paenibacillus larvae subsp. pulvifaciens strain SAG 10367 plasmid pPLP3, complete sequence) position: , mismatch: 11, identity: 0.667

gaaggaagtatttttacaaatatatttgctaca	CRISPR spacer
tttggaagtaattctacaaatatatttaaaggt	Protospacer
   ******* **.*************.  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

230835 : 247310

Bacillus_phage(66.67%)

plate,tail

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015212455.1\|230835_232725_-\|tail	phage tail protein	NA	NA	NA	NA
WP_015212456.1\|232706_233690_-	hypothetical protein	NA	NA	NA	NA
WP_015212457.1\|233692_237271_-\|plate	putative baseplate assembly protein	A0A1J0GW37	Streptomyces_phage	7.8e-13	23.9
WP_015212458.1\|237277_237664_-	GPW/gp25 family protein	NA	NA	NA	NA
WP_015212459.1\|237663_238371_-	Rhs element Vgr protein	NA	NA	NA	NA
WP_015212460.1\|238367_239435_-	phage late control D family protein	NA	NA	NA	NA
WP_015212461.1\|239447_240101_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_015212462.1\|240091_243184_-	hypothetical protein	NA	NA	NA	NA
WP_015212463.1\|243243_243711_-\|tail	phage tail protein	NA	NA	NA	NA
WP_015212465.1\|244015_244378_-	hypothetical protein	NA	NA	NA	NA
WP_015212466.1\|244389_244833_-\|tail	phage tail protein	NA	NA	NA	NA
WP_015212467.1\|244857_246012_-\|tail	phage tail sheath family protein	J9PVC2	Bacillus_phage	6.6e-30	29.6
WP_015212468.1\|246155_247310_-\|tail	phage tail sheath family protein	J9PVC2	Bacillus_phage	1.6e-39	35.7

DBSCAN-SWA_2

1396233 : 1475474

uncultured_Mediterranean_phage(20.0%)

integrase,transposase

attL 1463737:1463751|attR 1474949:1474963

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015213386.1\|1396233_1397709_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_015213387.1\|1397701_1398163_+	hypothetical protein	NA	NA	NA	NA
WP_015213388.1\|1398174_1398459_+	hypothetical protein	NA	NA	NA	NA
WP_015213389.1\|1399387_1400020_-	type I restriction endonuclease subunit R	NA	NA	NA	NA
WP_015213390.1\|1401182_1402703_-	alpha,alpha-trehalase	NA	NA	NA	NA
WP_015213391.1\|1402853_1405646_-	malto-oligosyltrehalose synthase	NA	NA	NA	NA
WP_015213392.1\|1405897_1407742_-	malto-oligosyltrehalose trehalohydrolase	NA	NA	NA	NA
WP_015213393.1\|1408581_1429275_-	DUF4347 domain-containing protein	A0A1B1IT51	uncultured_Mediterranean_phage	5.3e-37	33.1
WP_015213394.1\|1431054_1432140_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_015213395.1\|1432791_1433148_+	Spx/MgsR family RNA polymerase-binding regulatory protein	NA	NA	NA	NA
WP_015213396.1\|1433269_1435042_-	hypothetical protein	U5PVT3	Acinetobacter_phage	1.8e-18	26.7
WP_015213397.1\|1435031_1436096_-	AAA family ATPase	H6WG28	Cyanophage	3.6e-30	36.2
WP_015213398.1\|1436336_1436987_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_015213399.1\|1436989_1437340_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015213400.1\|1437452_1438268_+	PD-(D/E)XK nuclease family protein	NA	NA	NA	NA
WP_015213401.1\|1438264_1440487_+	stem cell self-renewal protein Piwi	NA	NA	NA	NA
WP_015213402.1\|1444612_1447591_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.8e-289	50.4
WP_015213403.1\|1447701_1448163_-	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_171815780.1\|1453609_1456255_-	CHAT domain-containing protein	NA	NA	NA	NA
WP_015213407.1\|1456218_1457007_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_015213408.1\|1457057_1457909_-	hypothetical protein	NA	NA	NA	NA
WP_015213409.1\|1458337_1458820_+	hypothetical protein	NA	NA	NA	NA
WP_015213410.1\|1458928_1459348_+	hypothetical protein	NA	NA	NA	NA
WP_015213411.1\|1459564_1460560_-	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_015213412.1\|1460556_1462074_-	DNA polymerase III subunit gamma/tau	A0A1L2BWV7	Bacteriophage	9.9e-50	36.2
1463737:1463751	attL	NA	NA	NA	NA
WP_042464670.1\|1465510_1466329_-	hypothetical protein	NA	NA	NA	NA
WP_042464673.1\|1466339_1466705_-	hypothetical protein	NA	NA	NA	NA
WP_171815781.1\|1466707_1467538_-	NACHT domain-containing protein	NA	NA	NA	NA
WP_085930372.1\|1467650_1468848_+\|transposase	ISAzo13 family transposase	NA	NA	NA	NA
WP_015213413.1\|1468835_1469015_-	hypothetical protein	NA	NA	NA	NA
WP_015213414.1\|1469241_1469763_-	hypothetical protein	NA	NA	NA	NA
WP_150110992.1\|1469906_1470383_-	hypothetical protein	NA	NA	NA	NA
WP_015213416.1\|1470491_1471109_-	TniQ family protein	NA	NA	NA	NA
WP_015213417.1\|1471092_1473567_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_015213418.1\|1473570_1474227_-	TnsA endonuclease N-terminal domain-containing protein	NA	NA	NA	NA
WP_081593733.1\|1474274_1475474_-\|transposase	ISAzo13 family transposase	NA	NA	NA	NA
1474949:1474963	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1566089 : 1636719

Bacillus_phage(20.0%)

tRNA,integrase,transposase

attL 1625516:1625534|attR 1629137:1629155

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081593666.1\|1566089_1567070_-\|transposase	transposase	NA	NA	NA	NA
WP_015213487.1\|1567307_1568216_-	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_015213488.1\|1568260_1568932_-	glutathione S-transferase family protein	NA	NA	NA	NA
WP_042465790.1\|1569303_1569648_+	DOPA 4,5-dioxygenase family protein	NA	NA	NA	NA
WP_081593667.1\|1569680_1570151_+	HAD hydrolase-like protein	NA	NA	NA	NA
WP_015213490.1\|1570653_1570890_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_015213491.1\|1570966_1571173_-	hypothetical protein	NA	NA	NA	NA
WP_015213492.1\|1571467_1571608_+	hypothetical protein	NA	NA	NA	NA
WP_015213493.1\|1571604_1572006_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_015213494.1\|1571998_1572271_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_015213495.1\|1572364_1572697_-	XRE family transcriptional regulator	NA	NA	NA	NA
WP_015213496.1\|1573320_1574664_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_015213497.1\|1574762_1576127_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_015213498.1\|1576378_1577917_+	amidohydrolase family protein	NA	NA	NA	NA
WP_015213499.1\|1578147_1578810_+	dienelactone hydrolase family protein	NA	NA	NA	NA
WP_015213500.1\|1579037_1580036_+	aldo/keto reductase	NA	NA	NA	NA
WP_015213501.1\|1580163_1581204_+	aliphatic sulfonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_015213502.1\|1581287_1583120_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.6e-33	35.9
WP_015213503.1\|1583100_1583469_-	hypothetical protein	NA	NA	NA	NA
WP_015213504.1\|1583461_1583707_-	hypothetical protein	NA	NA	NA	NA
WP_015213506.1\|1585064_1585310_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015213507.1\|1585794_1585992_+	hypothetical protein	NA	NA	NA	NA
WP_015213508.1\|1585979_1586168_-	hypothetical protein	NA	NA	NA	NA
WP_015213509.1\|1586257_1586533_+	hypothetical protein	NA	NA	NA	NA
WP_015213510.1\|1586830_1587226_+	Nuclease A inhibitor family protein	NA	NA	NA	NA
WP_015213511.1\|1587383_1587755_-	hypothetical protein	NA	NA	NA	NA
WP_015213512.1\|1588056_1589370_-	DNA/RNA non-specific endonuclease	NA	NA	NA	NA
WP_042464702.1\|1589469_1589667_+	hypothetical protein	NA	NA	NA	NA
WP_015213513.1\|1589743_1589992_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_015213514.1\|1589991_1590249_-	type II toxin-antitoxin system ParD family antitoxin	NA	NA	NA	NA
WP_015213515.1\|1593281_1594949_-\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_015213516.1\|1595112_1595688_+	TniQ family protein	NA	NA	NA	NA
WP_015213515.1\|1595831_1597499_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_085930359.1\|1597920_1599418_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_015213517.1\|1599683_1600850_-	glutathione-dependent formaldehyde dehydrogenase	NA	NA	NA	NA
WP_015213518.1\|1601224_1601707_-	SRPBCC family protein	NA	NA	NA	NA
WP_015213520.1\|1601781_1602900_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_015213523.1\|1606240_1606759_-	hypothetical protein	NA	NA	NA	NA
WP_015213525.1\|1608057_1609191_-	hypothetical protein	NA	NA	NA	NA
WP_015213526.1\|1609329_1611393_+	VWA domain-containing protein	NA	NA	NA	NA
WP_042464705.1\|1611508_1611703_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_015213527.1\|1612522_1616734_-	DEAD/DEAH box helicase	A0A160DHD3	Gordonia_phage	1.8e-40	28.1
WP_015213529.1\|1617235_1617838_-	GUN4 domain-containing protein	NA	NA	NA	NA
WP_015213530.1\|1618229_1619339_+	alkene reductase	NA	NA	NA	NA
WP_015213531.1\|1619982_1620684_-	Uma2 family endonuclease	NA	NA	NA	NA
WP_015213532.1\|1620842_1621757_-	methylenetetrahydrofolate reductase	NA	NA	NA	NA
WP_015213533.1\|1621816_1622824_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_015213534.1\|1623290_1624856_+	B12-binding domain-containing radical SAM protein	A0A0M4R1U9	Streptomyces_phage	7.9e-10	24.2
WP_015213535.1\|1625013_1625463_+	SRPBCC family protein	NA	NA	NA	NA
1625516:1625534	attL	NA	NA	NA	NA
WP_015213536.1\|1625877_1626447_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.6e-40	51.4
WP_085930373.1\|1626451_1628098_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_015213538.1\|1628087_1629059_+	ExeA family protein	NA	NA	NA	NA
WP_015213539.1\|1629605_1630211_+	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
1629137:1629155	attR	NA	NA	NA	NA
WP_015213540.1\|1630361_1630904_+	DUF2231 domain-containing protein	NA	NA	NA	NA
WP_081593738.1\|1631239_1633225_-	hypothetical protein	E5ES62	Bathycoccus_sp._RCC1105_virus	3.4e-50	30.9
WP_015213542.1\|1633617_1634919_-	EndoU domain-containing protein	NA	NA	NA	NA
WP_150111077.1\|1635495_1636719_+\|transposase	ISL3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

2393342 : 2430932

unidentified_phage(25.0%)

integrase,tail,transposase

attL 2421938:2421956|attR 2439199:2439217

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_171815821.1\|2393342_2398550_-\|tail	lamin tail domain-containing protein	NA	NA	NA	NA
WP_015214224.1\|2400361_2401327_-	NAD(P)-dependent alcohol dehydrogenase	NA	NA	NA	NA
WP_015214225.1\|2401544_2401730_+	hypothetical protein	NA	NA	NA	NA
WP_015214226.1\|2402454_2403915_+	nitrogenase cofactor biosynthesis protein NifB	NA	NA	NA	NA
WP_015214227.1\|2404017_2404356_+	4Fe-4S binding protein	NA	NA	NA	NA
WP_042465921.1\|2404519_2405785_+	cysteine desulfurase NifS	H7BUW1	unidentified_phage	2.9e-39	40.8
WP_015214229.1\|2405893_2406808_+	Fe-S cluster assembly protein NifU	A0A2H4N7M4	Lake_Baikal_phage	6.2e-23	47.2
WP_081593676.1\|2407011_2407452_+	AAA family ATPase	NA	NA	NA	NA
WP_015214230.1\|2407837_2408236_+	hypothetical protein	NA	NA	NA	NA
WP_015212319.1\|2408380_2409601_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_150111003.1\|2409786_2410053_+	hypothetical protein	NA	NA	NA	NA
WP_015214231.1\|2410214_2410493_+	hypothetical protein	NA	NA	NA	NA
WP_042465925.1\|2410582_2410843_+	hypothetical protein	NA	NA	NA	NA
WP_015214233.1\|2410835_2411255_+	hypothetical protein	NA	NA	NA	NA
WP_015214234.1\|2411403_2411646_+	hypothetical protein	NA	NA	NA	NA
WP_015214235.1\|2411638_2413066_-\|integrase	phage integrase XisA	NA	NA	NA	NA
WP_015214236.1\|2413774_2414704_+	nitrogenase	NA	NA	NA	NA
WP_015214237.1\|2414798_2416202_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_015213536.1\|2418678_2419248_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.6e-40	51.4
WP_085930373.1\|2419252_2420899_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_015213538.1\|2420888_2421860_+	ExeA family protein	NA	NA	NA	NA
2421938:2421956	attL	NA	NA	NA	NA
WP_042464840.1\|2422162_2422351_-	hypothetical protein	NA	NA	NA	NA
WP_015214239.1\|2422387_2422804_+	hypothetical protein	NA	NA	NA	NA
WP_015214240.1\|2422901_2423372_-	hypothetical protein	NA	NA	NA	NA
WP_015214241.1\|2423713_2424988_-	ParM/StbA family protein	NA	NA	NA	NA
WP_150111088.1\|2425436_2427335_+	plasmid recombination protein	NA	NA	NA	NA
WP_015214243.1\|2427586_2427808_+	hypothetical protein	NA	NA	NA	NA
WP_042464843.1\|2427797_2428217_+	putative toxin-antitoxin system toxin component, PIN family	NA	NA	NA	NA
WP_015214245.1\|2428597_2428891_+	hypothetical protein	NA	NA	NA	NA
WP_015214246.1\|2428964_2429717_-	sigma-70 region 4 domain-containing protein	NA	NA	NA	NA
WP_015214247.1\|2429912_2430932_-\|integrase	tyrosine-type recombinase/integrase	A0A0H3V0V1	Geobacillus_virus	5.0e-05	21.8
2439199:2439217	attR	NA	NA	NA	NA

DBSCAN-SWA_5

2440309 : 2503104

Enterobacteria_phage(20.0%)

integrase,transposase

attL 2432104:2432155|attR 2495008:2495059

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2432104:2432155	attL	NA	NA	NA	NA
WP_085930373.1\|2440309_2441956_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_015213536.1\|2441960_2442530_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.6e-40	51.4
WP_015214253.1\|2442922_2443345_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_015214254.1\|2443971_2444364_-	type II toxin-antitoxin system death-on-curing family toxin	A0A1B3AYM0	Gordonia_phage	2.3e-06	35.0
WP_015214255.1\|2444360_2444585_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_015214256.1\|2444881_2446606_+	VWD domain-containing protein	NA	NA	NA	NA
WP_081593742.1\|2446969_2447221_-	CopG family transcriptional regulator	NA	NA	NA	NA
WP_015214259.1\|2447460_2448189_+	hypothetical protein	NA	NA	NA	NA
WP_015214260.1\|2448185_2449142_+	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_052334519.1\|2449237_2450872_-	hypothetical protein	NA	NA	NA	NA
WP_171815786.1\|2454952_2455120_+	hypothetical protein	NA	NA	NA	NA
WP_015214261.1\|2455422_2455665_+	hypothetical protein	NA	NA	NA	NA
WP_015214263.1\|2456121_2456775_+	AAA family ATPase	B0ZSI1	Halomonas_phage	1.1e-42	44.5
WP_015214264.1\|2456761_2457031_+	hypothetical protein	NA	NA	NA	NA
WP_015214265.1\|2457156_2457429_+	hypothetical protein	NA	NA	NA	NA
WP_015214267.1\|2457912_2458995_-	photosystem II q(b) protein	A0A127KM98	Cyanophage	1.6e-190	88.0
WP_150111091.1\|2459209_2459518_-	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_015214269.1\|2459976_2460486_+	hypothetical protein	NA	NA	NA	NA
WP_015214270.1\|2461138_2461936_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_150111092.1\|2461984_2463208_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_015214272.1\|2463929_2464526_+	hypothetical protein	NA	NA	NA	NA
WP_015214273.1\|2464787_2465228_+	cyanase	NA	NA	NA	NA
WP_150111005.1\|2465458_2465764_+	fertility inhibition FinO-like protein	A0A2H4PAR5	Aphanizomenon_phage	8.7e-22	50.9
WP_150111093.1\|2466513_2469597_+	DUF3854 domain-containing protein	B0ZSI4	Halomonas_phage	1.1e-10	23.2
WP_015214276.1\|2470362_2470899_+	HNH endonuclease	F5B475	Synechococcus_phage	1.3e-20	38.5
WP_015214277.1\|2472086_2472863_+	HNH endonuclease	W0TWB1	Staphylococcus_phage	7.9e-19	60.5
WP_015213536.1\|2474102_2474672_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.6e-40	51.4
WP_085930377.1\|2474676_2476323_+\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_015214279.1\|2477479_2478643_-	DUF3854 domain-containing protein	NA	NA	NA	NA
WP_015214280.1\|2478914_2479235_-	hypothetical protein	NA	NA	NA	NA
WP_015214281.1\|2479968_2480235_+	hypothetical protein	NA	NA	NA	NA
WP_015214282.1\|2480395_2480665_+	hypothetical protein	NA	NA	NA	NA
WP_015214283.1\|2480712_2480982_+	hypothetical protein	NA	NA	NA	NA
WP_042464852.1\|2481063_2481390_+	hypothetical protein	NA	NA	NA	NA
WP_015214284.1\|2481649_2482054_+	hypothetical protein	NA	NA	NA	NA
WP_015214286.1\|2482360_2482660_-	hypothetical protein	NA	NA	NA	NA
WP_015214287.1\|2482663_2482981_-	hypothetical protein	NA	NA	NA	NA
WP_015214288.1\|2482980_2483253_-	hypothetical protein	NA	NA	NA	NA
WP_015214289.1\|2483230_2483821_-	hypothetical protein	NA	NA	NA	NA
WP_015214290.1\|2483861_2484227_-	hypothetical protein	NA	NA	NA	NA
WP_015214291.1\|2484412_2485057_-	hypothetical protein	NA	NA	NA	NA
WP_015214292.1\|2485058_2485940_-	hypothetical protein	NA	NA	NA	NA
WP_171815822.1\|2485940_2487950_-	hypothetical protein	NA	NA	NA	NA
WP_015214294.1\|2488480_2489029_-	hypothetical protein	NA	NA	NA	NA
WP_015214295.1\|2489028_2489343_-	hypothetical protein	NA	NA	NA	NA
WP_015214296.1\|2490591_2491215_+	RusA family crossover junction endodeoxyribonuclease	NA	NA	NA	NA
WP_015214297.1\|2491390_2492125_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_015214298.1\|2492190_2492766_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_015214299.1\|2492871_2493387_-	peptidylprolyl isomerase	A0A1V0SCU1	Indivirus	4.6e-15	36.4
WP_015214300.1\|2493542_2494121_-	hypothetical protein	NA	NA	NA	NA
WP_171815787.1\|2495050_2496583_-	slipin family protein	NA	NA	NA	NA
2495008:2495059	attR	NA	NA	NA	NA
WP_015214302.1\|2497373_2497619_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_015214303.1\|2497615_2498020_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_015214305.1\|2498645_2499248_-	AAA family ATPase	NA	NA	NA	NA
WP_015214306.1\|2499260_2499485_-	hypothetical protein	NA	NA	NA	NA
WP_015214307.1\|2499484_2499904_-	hypothetical protein	NA	NA	NA	NA
WP_042465955.1\|2499896_2500112_-	hypothetical protein	NA	NA	NA	NA
WP_015214309.1\|2500235_2501465_-	DUF4935 domain-containing protein	NA	NA	NA	NA
WP_150111077.1\|2501880_2503104_+\|transposase	ISL3 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_019772

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_019772_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019772_1

10003-10158

Unclear

A:N

Consensus_repeat	Method
CCTTGCAACTGATTTCCTGTTTGATTCTTTTCGTATTTGATACCATTAAT	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NC_019772_1

>merge|NC_019772|1|10003-10158|CRISPRCasFinder
CCTTGCAACTGATTTCCTGTTTGATTCTTTTCGTATTTGATACCATTAATCAACAAGCTATTATTTGTTGACAAGCATTAATTTTTATTTTCATCAAAATAAACTTCCTTGCAACTGATTTCCTGTTTGATTCTTTTCGTATTTGATACCATTAAT

>NC_019772|1|1|10003-10158|CRISPRCasFinder
CCTTGCAACTGATTTCCTGTTTGATTCTTTTCGTATTTGATACCATTAAT	CAACAAGCTATTATTTGTTGACAAGCATTAATTTTTATTTTCATCAAAATAAACTT
CCTTGCAACTGATTTCCTGTTTGATTCTTTTCGTATTTGATACCATTAAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019772.1\|WP_015217548.1\|120_816_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217558.1\|10995_11655_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217549.1\|944_1253_+\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217555.1\|9022_9352_-\|XisI-protein	unknown	unknown	gnl\|CDD\|370165
NC_019772.1\|WP_015217561.1\|12468_15195_-\|DEAD/DEAH-box-helicase	cas3	cd09710_cas3_CAS-I-D	gnl\|CDD\|224126
NC_019772.1\|WP_015217560.1\|12064_12322_-\|type-II-toxin-antitoxin-system-ParD-family-antitoxin	unknown	unknown	gnl\|CDD\|274227
NC_019772.1\|WP_015217562.1\|15422_15833_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217554.1\|7097_8963_+\|type-IV-secretory-system-conjugative-DNA-transfer-family-protein	unknown	unknown	gnl\|CDD\|226036
NC_019772.1\|WP_015217553.1\|5731_6673_+\|DUF4351-domain-containing-protein	unknown	unknown	gnl\|CDD\|316753
NC_019772.1\|WP_015217567.1\|22590_24090_-\|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl\|CDD\|237862
NC_019772.1\|WP_015217551.1\|3624_4353_+\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217563.1\|15878_16061_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217566.1\|21598_22594_-\|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl\|CDD\|180982
NC_019772.1\|WP_015217559.1\|11756_12065_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|226194
NC_019772.1\|WP_015217565.1\|19738_21331_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197231
NC_019772.1\|WP_015217552.1\|4491_5580_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235033
NC_019772.1\|WP_015217564.1\|16268_19742_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NC_019772.1\|WP_015217556.1\|9348_9990_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_150111130.1\|1541_3473_+\|M23-family-peptidase	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_019772.1\|WP_015217553.1\|5731_6673_+\|DUF4351-domain-containing-protein	gnl\|CDD\|316753	pfam14261, DUF4351, Domain of unknown function (DUF4351). This domain is found in bacteria, and is approximately 60 amino acids in length.	2.01776e-19
NC_019772.1\|WP_015217566.1\|21598_22594_-\|DNA-polymerase-III-subunit-delta	gnl\|CDD\|180982	PRK07452, PRK07452, DNA polymerase III subunit delta; Validated.	3.94155e-77
NC_019772.1\|WP_015217565.1\|19738_21331_+\|hypothetical-protein	gnl\|CDD\|197231	cd09133, PLDc_unchar5, Putative catalytic domain of uncharacterized hypothetical proteins with one or two copies of the HKD motif. Putative catalytic domain of uncharacterized hypothetical proteins with similarity to phospholipase D (PLD, EC 3.1.4.4). PLD enzymes hydrolyze phospholipid phosphodiester bonds to yield phosphatidic acid and a free polar head group. They can also catalyze transphosphatidylation of phospholipids to acceptor alcohols. Members of this subfamily contain one or two copies of the HKD motif (H-x-K-x(4)-D, where x represents any amino acid residue) that characterizes the PLD superfamily.	7.99391e-27
NC_019772.1\|WP_015217555.1\|9022_9352_-\|XisI-protein	gnl\|CDD\|370165	pfam08869, XisI, XisI protein. The fdxN element, along with two other DNA elements, is excised from the chromosome during heterocyst differentiation in cyanobacteria. The xisH as well as the xisF and xisI genes are required.	2.02561e-56
NC_019772.1\|WP_015217559.1\|11756_12065_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|226194	COG3668, ParE, Plasmid stabilization system protein [General function prediction only].	2.72373e-23
NC_019772.1\|WP_015217552.1\|4491_5580_-\|hypothetical-protein	gnl\|CDD\|235033	PRK02363, PRK02363, DNA-directed RNA polymerase subunit delta; Reviewed.	0.00777429
NC_019772.1\|WP_015217561.1\|12468_15195_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|224126	COG1205, COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster [General function prediction only].	1.64949e-86
NC_019772.1\|WP_015217560.1\|12064_12322_-\|type-II-toxin-antitoxin-system-ParD-family-antitoxin	gnl\|CDD\|274227	TIGR02606, Antitoxin_ParD, putative addiction module antidote protein, CC2985 family. This bacterial protein family has a very similar seed alignment to that of pfam03693 but is a more stringent model with higher cutoff scores. Proteins that score above the trusted cutoff to this model almost invariably are found adjacent to a ParE family protein (pfam05016), where ParE is the killing partner of an addiction module for plasmid stabilization. Members of this family, therefore, are putative addiction module antidote proteins. Some are encoded on plasmids or in prophage regions, but others appear chromosomal. A genome may contain several identical copies, such as the four in Magnetococcus sp. MC-1. This family is named for one member, CC2985 of Caulobacter crescentus CB15. [Cellular processes, Other, Mobile and extrachromosomal element functions, Plasmid functions].	7.35948e-13
NC_019772.1\|WP_015217564.1\|16268_19742_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	8.13893e-46
NC_019772.1\|WP_015217554.1\|7097_8963_+\|type-IV-secretory-system-conjugative-DNA-transfer-family-protein	gnl\|CDD\|226036	COG3505, VirD4, Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion].	3.5018e-56
NC_019772.1\|WP_015217567.1\|22590_24090_-\|DNA-polymerase-III-subunit-gamma/tau	gnl\|CDD\|237862	PRK14948, PRK14948, DNA polymerase III subunit gamma/tau.	2.18346e-152

>NC_019772.1|WP_015217556.1|9348_9990_-|hypothetical-protein
MELEINDWKQLFEISASHSPLTISLPTIALANPPYCKINSISDSELSRFEMAYKWKEQENGSYIITSKLRNQIEQECLFVEQCLRQVQPGEIVCVLLSNGILSSSQQAYFRRWLLEEMAVLIASIQLPPENFQVECELGIVTSFLILKRKGGNLSVPEDYPIFMAVVEKIGFDSRGRRLFRPITKEQEKQEIDSDLPTIVEEFKQFIKEEIIP
>NC_019772.1|WP_015217555.1|9022_9352_-|XisI-protein
MKKPDKYRQIIQELLTAHATPNEPNIECQLIFDSEHDHYQLLDVGWQDLNRIYSCYIHLDIKDNKIWIQHNMTEADIGQELVERGVPASDIVLGLHPPYKRPYTKYGVA
>NC_019772.1|WP_015217554.1|7097_8963_+|type-IV-secretory-system-conjugative-DNA-transfer-family-protein
MNLYQKNLPNSHITANSTLIEVSTYQPTLANIDFGKFFQQYNNPQGWTMMAGLLVVLILLQISGTGKGKITTGTVCGVSEKLAATNLAFKQIQEHKHNKVTLWSGTPRYWAKGKWRGLMANLQTMLGAAPTVWFPHAERGTLVIGAPGSGKTYSTIDRMLESAMQQGFPILLYDKKGDQMRLHAPLAARYGYKVRVFAPGEAFSGVINPLDFMRDARDGVMAGEIGQVINRNAASGGKSDEFFAKAGDLLAKALLQLVKGSPYPDMAMLYAVLRLPKLVQRLDHAVQSKRLDEWVATSFIQFLSAKDAEKTVSGILTTAAGTFSSFIQADLLRAFIGKSDIPTQLSGREMVVFKLDDERRSVVGPLLAAAMHLMIVGNLSRPRKDPLIISLDELPSIKLDRLPQWINEYRSNGACFILGIQSLEQLYDIYGDKMGSAIASACSTHVLFNPGNYKTAEDYSKRYGEKEVLIKNRTTGRTLGGQMSRSISWSENLQKMPVISADEILKFPQGKCVITSPGYSSGGQASIPYPLIIPVSKTDEKRAKESEALWDTQVRLALESQVTIPDLKMLTQALYDRIEEAGRMLPLPDEDVATVQESSNHQEPDVLENFTTRVYQTPGLQ
>NC_019772.1|WP_015217553.1|5731_6673_+|DUF4351-domain-containing-protein
MTKNEITANYDESWKEALNEYFDSFLSFFFPVAYEAIDWTKPPESLDKELQQITASSETEKRIVDKLYKVWLLDKTQAWILIHIEVQSNYDVDFQERMYTYNYRAFDLYHKFVVGLAILGDTSSTWRPNSYHQAMLDCELSLKFPIAKLLDYESRWTELESNPNPFAIIVMAHLKTKATTGNLSEREQWKWVLIRGLYERGLTREQIVKLFKIIDKMMTLPKELQRGLVTKIKHLEEEKQMPFISPTEELAMERGEQQLIIRQLNRRIGGIESSFIETIRTLTIEQLELLGEALLDFSSVTDLEEWLQNKPES
>NC_019772.1|WP_015217552.1|4491_5580_-|hypothetical-protein
MVKSRTTNNSKHPHQSPPKTAATKPKTTKARLTEPDDYDFEETEFEIDPELFNDHYNQVRKPLLPYGIVVNDKPAGLLIPEDQLEKAGWLEMPEEDDLTTVTLTEDVTGLLITEGRLLVLAFAPEYIRYKSDVEDVGGSFVGLYDDYRHSLDKRTMDVCSEHAIMFLDDKNQPLHTTPVVVRFKNVALWSFKSVREEFYRSLEKTFADYFQVPFSGKSDKWRSLGVLEIEFRAIKEGEGKNKHNCCKTVAYTKPTVDNFPQLYLGKTTAKSLIWQQHDAIAGFNEPQSLPANPGESVSVEVEVLPPNKNKNKGKTQTVRKSKPATKPPRKIQVIEDDDFLDEDDDLETDLDDDDFEFDDDDE
>NC_019772.1|WP_015217551.1|3624_4353_+|hypothetical-protein
MTNLSTTSISSDPQTKNFSDTDLHSKKQFEQVTADKLVSSLSASSTQSQSLKTTGYQLPEPPMRIRYGVHWFRVGLSIFLLLSVLCGLGGCSLNAATVTWHKAVNLVSSSVVEQVIVENTDLNPQASVDNILAVNVAGKDGKLTIFNFNTPDVCGTLGCLYAGYWFKPNQPIIQVFLSYLNPTLPPGKQLLAVGENRYQALPCIKVLQTEKQQLRQLNFCFNSNRYQLADSQLLATMNKSPK
>NC_019772.1|WP_150111130.1|1541_3473_+|M23-family-peptidase
MSFMIYSVTVQAANSTLNNRNLPTRIVEVANSQSRLPANKLLLPDWNRISLNQLPGISQSGAIDGSPYSQTLGYDLSRTWTVGMTPDQYLKLGDISEALQTEKFSLQAIGDITSIDLNKIALSEFPLIAEQTLSHLAKVVPQLAQTPVKDIQPVATLLKTQGIEASNLTLAQVLTQYEVGNIKLGEIDLSKFSLTSIPNLETVPMQDFTNWMNSFVKNIPGLGQVPLRLMPNPINEIGNLVMRIDAVYGIAENHRNNTISGSDVQGFSVPCTQKDCAYLELDDLENVGKSDAYGERSYRLSLEGKQWISGKYQEVEGGWGILKAVNNGREPTGRLPFGKAFKVVVMETDETADTVDTALYFRFCAWKMGCSPYFIGPIPFFSYQVNALMFVGNLDNQSEQSVSGASVNTTSTPTGANREVKGNPSQSSIATNQINPCTFTRANRSIVSQSFYGVNLPLLGNAIAEIESAGGGDYQAVGVHTCADGGLNCGRGLGRYQFMSYNPYAVRLIAAKSGGEEFLERVKQGYQPTEAELFEFFPPADQDRAFMADIANKIQVTQTEIDPITGQSFTGERLIERVAQKHFGGDNSKVDASSSDVFGRLSLKDYGKTALALYGNNNSDNGTLTCIPSLTSRYISNAQNIGN
>NC_019772.1|WP_015217549.1|944_1253_+|hypothetical-protein
MNQEPALNQNSEDENNRQIKSAKGYQSHGYSLEESSYEDQNNPWTTDRFEDGYQENVFEINFGDTPYTESAANPNPKLPGYGSGSGYKSKKSQQSTSPELEL
>NC_019772.1|WP_015217548.1|120_816_-|hypothetical-protein
MAQINLIPPEVMAEINNHKNTKLPDNTLKMLQILASLNTPKELLATLLEIAEFSIHHIRYLAGPLVIHGNAWSDTIPQWLKFACIQDRLELICNEYEQNQVGEYATATEVLTYMMPASYEAPLHRDYADLYLWVGNEVLTKYNKLPKDCQSFYEFIDGNTSDTSNKSIIHFQQVKNDFHDISQSIRRSIVKHAAQEGWGKRRVNSKSKIDSIENTPPPESSSNSSVQMDLF
>NC_019772.1|WP_015217558.1|10995_11655_-|hypothetical-protein
MPIINLADIQQIKKTQQQLLFPYQKHHSNHSEFDYIIADSFHLLMKQLFLQLPVEPLLNAHPQIAQWVAQVQELAPELFHTRKKLLVDNPVIAPLMINNDNYFIQVTTNIAFKQGIPRIYEWAVRHPQLSWQDRVKLWTTTIQYSVIPNQMQLVILALDPVKPPQRLNIRWNKKYHHQTERWLIKLLNQPQENDAQSNQINQEITSSMINLADISEVSI
>NC_019772.1|WP_015217559.1|11756_12065_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MAIILKKPLAEADLLDTWDFIANESLEKADSFLQKIENKLKILAENPSMGRKRDELLPGLRSFPVGSYLIFYYPLNQGIEVIRVFHGARDIPSFFEDSLENE
>NC_019772.1|WP_015217560.1|12064_12322_-|type-II-toxin-antitoxin-system-ParD-family-antitoxin
MNVSLTTELEKWVHSKVESGMYTSASEVIREGLRLLKEQDALKGIRLAELRREIQQGIDSGESTPLNMSEIIAKAKQQRQEKQSQ
>NC_019772.1|WP_015217561.1|12468_15195_-|DEAD/DEAH-box-helicase
MNTPNYSLLLQSLWTPPTTPIAENSHTNNHPPEPTEITEFLAEEILYQQTIPATESNLKTIPKDLPKQLIKALQSLGITQLYSHQIKALQAIRTGKSFILTSPTASGKTLSTYPGIIEGCINQEHRALAFYGLRALALDQFHKISQLLSTIPPKYRPVLAMITGDVKSAEREQILASEPHILGVTPELIHFQLKQVWKSPNWANFYQRLRYILIDEAHTLSGSYGANMAWLIRRIKLAVDHYGGDSQKLQFIFLSATCGNPKQLALKLSGLKPTKLNPKPLIWIRKSGAASPPRQVIVTQPSYNLTADTARIIQFLLNQNKSGIAFCNSRRSVREVTELLKSNQVTAFYSGITAERRAEVVNQLQSGIIKWIIATEALEAGIDLPELECCVLRGWPGSKMAYQQRSGRAGRSQPGLTVLLPNAFNPIDCYVAEHPEMLVSGEAEEVFFNDEYPIFAAKHLMCAAAETGIPTNKIKHYFGAAAFDVAKLLLAQGHLHKGRNGLWAKGYPHKDVNFRGGLSQTTIKLVDAISGEELEEISEDIAHREVHPQAIYKRQNAKGEMLTYQCIFLDLNSKRAILKQTTDKAIFTVATTVSQTSSLTVLTDPVNLPLLFSSDGIEEKKQEEQEQKIKGKVSHKTDIVVIGKSVKEEQRIKEKVSHPATLSEVEECQEYLTLELSFGEVKHITSGYSLMTQIYEQTCLNKRCLNYKEPLPQQPRCPLCRKLTRKAVIVKTLSEAKFEQPFRTQFSAPMVKVTINSSAREYIQQFAKETRTSLTRSQEPIPSGYQQLWEYSSPFIAMHSFGHQIMRALQLVARVDPKQVNFTVVKELGENSNYTGYFYDTSDGGNGAAEAVFKHLPKLAEVGRAIARDCNCHTGCAKCLIQHGCPDGNTALLKQMGLVLLDAIATSE
>NC_019772.1|WP_015217562.1|15422_15833_-|hypothetical-protein
MNIKQNILEVSGVEISKSILIDLQKLSSCSGEPIASVYTDNLLRTMRTMRDKLPFDPYTEVVMALHDALAYSNRWIDYNASQYQGVCELLTSLVNQETINNSSVETAILTLENLGFDTLPFGVKLDESLDIDKDEE
>NC_019772.1|WP_015217563.1|15878_16061_-|hypothetical-protein
MNTPNYSLLLKSLWTPPTTPIPENSHPNHHPPEPTEITEFLGEEILWQQTITNTDKYVLK
>NC_019772.1|WP_015217564.1|16268_19742_+|protein-kinase
MKARLLNGIYTLMPNPKSGGMAKIYKARDINNDNLVAVKIFENGQIEQEITDESFRREVSALKELKHPRIVQLIDSGLDEETGHNFLVLEWMESNLATSLKESPLAGWDEFWERVGLPLLEALAFSHNRECIHRDIKPNNILINTEGIIKLADFGISKVKRYLQPTVTLREFVSRPYSPPEEDDGSYTYTRDVFSFGVLILKCLTEVELITYDTIKQAIKQFDASPEIITIIERSVSLEPSERQHNAEVLLVEIQAIQEKRKKEYQVKQGSCYLKLPSRIDKIADELEADSNNEIEKIILQDLNSGCAMCRFEKRNPVDREDKYEENQYKIFGTDYSYHVKIDDRDQEKLVILNVMNLSSSILEENRNRYWHPPYNFKFGNSSNRLEDKTVISKLKLLIEEYESEIRQKQAEEEKQRLFRNWENILRAKTDWEKEHQPPLNYIEVTRQENRAIFTLASITDENLVEQPRLVIVNNRTLLSGNVEEVKEDKLTLYINSGDPERLPKSGELRFDTRAAEYALRQQKNALEAIKYDRAARSDIRSLLITPQEVKTPTTEENIKFIQSLNQSQKETVEAALGTQDFLVVEGPPGTGKTTFITEVILQTIRANPQARILLTSQTHVALDNALERIKKQNPALKMVRIGNHEKVADNIHDLLLEEQMEHWKSEVFRRSQGFLENWSKKHNLSPQEITMANLFQKLREALMELDRLKKEIEIFQQEQYEITQTEELKAYFENYNLNDLRSEIHKNLPDDINREWEFINDKIKGLENKTKEIRDQRKDTVKELHQVSQIDEEELLKMSLSELEGYENILIDLNQPEAKKLRTLMKVQQDWFDIFGRADSDRFNTAFLKQAQLVAGTCIGLARSIPEIEFDLCIIDEASKATATEVLVPIARSHRLILVGDTKQLPPFQDEASRNFDFLNKYNLDSEEIKETLFAYLIKTLPDSNRKILTIQHRMVAPIGNLISECFYQGQIESARDDLDNDLTQVIPKPVTWFTTSKLPDCREQAANGSYNNMAEVNVILKILEQINKMAITVNKKYGIAVLTGYSAQLKLFKRKLDSELSNWEALTIKYNTVDAFQGQEADIAIYSITRSNKKASLGFLRDTERMNVALSRGKVGLIIVGDHNFCRSLNYNPLHTVLNHIESHPESCSLFEVKS
>NC_019772.1|WP_015217565.1|19738_21331_+|hypothetical-protein
MILDELDTQNTNDTDEIARRYDNRPGFELVSVVEVGLPVTKINLTALTLVRKPIPPIEEFILKAINIGLSSLEEISYFLGLEELIIKDSIINLRQAENIDLIASLGSSIQEWKLTKKGKTTLEEARIITPEERGYQINFDKMLWKPRRYGSWEDNKSLLRHKNLKNNNIVEIPYYPARTPELADLNLKDVEKIIQEKENEKDGRRKKEEERDFKRDFIGLKKIERRDNFFQPALALVYKQKQGNDWQITFAIDGRISEVHESAFTRSKGPKKDRIIKELKESFSTQIRYAKILAKEKFGDEFLTLAIEYEKQIDSVREEINNRSNIIQTDIDSTRQTLEKVNDDEQKVALEEKLNNALEEIKQLQEQLEQLISSTPIRFIKTYDHRPLFEEALKNSQKRLLIISPWIRATATNQWLVNQLEKLVRRGVKVFIGYGYGDKDEKDRRDYDIKAEEAIQKLAKRYPDNVVFKRLGDTHCKILISDQRFAIVGSFNWLSFKGDPNRTFRDERSTLVSDPNKIDELFNDEITRLI
>NC_019772.1|WP_015217566.1|21598_22594_-|DNA-polymerase-III-subunit-delta
MIVLLTGDDEYAIQSQLNQYKAEIDAQWLTLCYHRFPAVQLDKALSVARTRSLTGGKKLVIVENCHLKQWGDPELETLQQLVQVPKSTILVFVANNVDKRLKVYKHLVKYGKLLEFSLIPPWRYDLIEQAIVSLAARLYTNTTDNAVTPKKIKLVLSEEAVTYLAQAIGNDMTRAASELRKLSIYAQGRKLELAEVQELVPCQTQNSLQLAAAMREGKSHQVLQLLDDLLSRCQPLMVIVSTILTQFRTWLWVKSAIVSGVKKDGELAQLCNISNPRRVYYLRQEVANTSINALAKAVTMILDLEMSIKRGADGRDLLVVILGVCRLFQVV
>NC_019772.1|WP_015217567.1|22590_24090_-|DNA-polymerase-III-subunit-gamma/tau
MSTVALHQKYRPQTLAELVGQPYIKTALTNAIKHLQIAPAYLLTGSRGTGKTSTARIFAKSLNCLNSKKPTDKPCGICQSCRAIETSNSLDVSEIDAASNNGVDDARALIERCTLAPVAGRYRIFILDENHQLTTQSQNALLKCIEEPPPHVIFILCTTEQHKVLPTIISRCQVFNFRTLSIKTIVQHLRIIADAESIAVDDEALSAIARLSDGGLRDALQLLGQASLLDVDITAHHVMEIVGGVTEAELIAILQAISTNNTFNLLQVARVLVDSGKTPKLIISNLLQTYRDLLIIKSAPQEQALLTGCVSHTQLKAFAKHWNFETLNLSLGELQKAENYLRYTVNATVWLEVCLLNLLPGLLPGGATKTVNVKPGHDGKLLPTYGTYTINKVTDKPVDDPGKDSLLPAVATNTANLAQIWQQVMDKAKPNHQKLLAHASLVKLQGSKAILEVTPAYQKKFENGKDAIAKMLERATQSPKPLTVLIKTANLNNNGRVTG

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Crispr_ID: NC_019772_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019772_2

31583-34510

A:N

Consensus_repeat	Method
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	PILER-CR
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CRISPRCasFinder
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CRT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	PILER-CR

39 spacers

cas6,WYL,csx1,cas10,csm3gr7,csx10gr5,csx19,cas3

The CRISPR arrays of NC_019772_2

>merge|NC_019772|2|31583-34510|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACATACGCGCTGCGAGTGCGGTATGTGTGGTAAGTGAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACATAGACAAGAACTAGAACGTAAAGAGATTATCTGGAAAAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACCTTACTCCTACTATTCCTTACTTTGTTTTTCCATGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACATAATTTAGATCCATTTATTTATCGTTGGAAATGGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTCGATAGTGAATCGTGGGATATTTTTGTTCACAAGAAACGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACACTGATATCCAGCAAGTCTCGTGGGCTTCATCACAAATAATGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTTGGCAAGACATCCTACAATATAGATACCTTTTGTTTTGTTGGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTTGGGCGTAGCTTCTGAGAAGCTAGAAATTCCTTCAGATGTGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACAAATTATTGCGATCGCGAAGGCAAGAAATATGAAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACCAATAACTGATATTCCTAAACTCCACAAATAAAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTATTTGACCTTAGTGCCTGGTAAGTGGGGTGCAAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTTCTGAGCTTTTACAACTCCGGCCGCGATTAAAGGGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTAAAAAAAATCATGGCTACCACACAAACTGCTCTTAAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACGATATAACTTTAATGCTTTAATGTAGACGATACTCCTTTGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACAACTAAACTACCAGAATCTGTACTTATATCTAGGAGAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTCAATTTGATAGCTGCCAGGAATCGGACAAGGGGCAGGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTTCATTAAATTGTCGAGGTTCAGTTTTGATTGATAAATGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACCATCAACCTCAATTAAATTAAGGGTATCTTCAACTTTAAAACGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACCTGATGAAAATCATAATTGCTGATAACCTGTGTAGGGATGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACGGGGGCTAACTTATCTAGGGTTAGGTTTTTGGATCAATGCTAAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACCTATCTCCAATCGAGTCTTATCAAATCTTGACTGGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTATCTAGTCTGTAAAAAAGTCTGGTACATCGACTGGTGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACCCAGATAAGGTTTGATAGCAAAGGGGAGTTTAATCTTGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACAAGGCAAAATTCATATTATTCAACTCCGATGCTATGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACAACCTGTTACAGGTTATGCTAGATAGGTACTAGCAGTGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACATTCCATTAAAAGAAGCTGCCAAAAAACTGAACTATGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTATTGTTGCAACTGTCTGGTATTGGGATAGAGATGAAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACCTGTAGACGACATAATTGAGTCTCCAGACTTTTGGATGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTTTACAGGGAATCTTAAAAGAAATTCATAAAATCATGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTTTTTCTTAAATTAGAAATAGAATTTATAACATCTAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTTTCAACAAAGGTTTTTTGTTCCGTTTCATTGTCAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTCTCGAACCGGTCAAGCGATCGCTAAAGAAAAACTTATTAATGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACGTAGCTTACAAAAACATCTTAGGCAATATAAAAGCCGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTTTTAAGGTGCAACGAGACTGGGTATATACCGTTGAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACAGTGTTCCCTTTCCCTGGAACAACCAAGCCTATCACGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTTGAAGTTGTGCCAAACTTTTCCGAATCCGGCTATTTGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACTAGAGTCTTACATAGCCTCGAATTTTGTGTCTATAGATGAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACATTCACTGGACAGATGCAACAGATTTTAAGGTTAATGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACCTAGAAAATAGTAACGTTTTAAAGCCAGAAGAGGTGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC

>NC_019772|2|1|31583-32220|PILER-CR
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATACGCGCTGCGAGTGCGGTATGTGTGGTAAGTGA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATAGACAAGAACTAGAACGTAAAGAGATTATCTGGAAAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTTACTCCTACTATTCCTTACTTTGTTTTTCCAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATAATTTAGATCCATTTATTTATCGTTGGAAATG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TCGATAGTGAATCGTGGGATATTTTTGTTCACAAGAAAC
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ACTGATATCCAGCAAGTCTCGTGGGCTTCATCACAAATAAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTGGCAAGACATCCTACAATATAGATACCTTTTGTTTTGTTG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTGGGCGTAGCTTCTGAGAAGCTAGAAATTCCTTCAGATGT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACAAATTATTGCGATCGCGAAGGCAAGAAATATGAAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACCAATAACTGATATTCCTAAACTCCACAAATAAAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TATTTGACCTTAGTGCCTGGTAAGTGGGGTGCAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTCTGAGCTTTTACAACTCCGGCCGCGATTAAAGG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TAAAAAAAATCATGGCTACCACACAAACTGCTCTTAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	GATATAACTTTAATGCTTTAATGTAGACGATACTCCTTT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AACTAAACTACCAGAATCTGTACTTATATCTAGGAGA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TCAATTTGATAGCTGCCAGGAATCGGACAAGGGGCAG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTCATTAAATTGTCGAGGTTCAGTTTTGATTGATAAAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CATCAACCTCAATTAAATTAAGGGTATCTTCAACTTTAAAAC
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTGATGAAAATCATAATTGCTGATAACCTGTGTAGGGAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	GGGGGCTAACTTATCTAGGGTTAGGTTTTTGGATCAATGCTAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTATCTCCAATCGAGTCTTATCAAATCTTGACTG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TATCTAGTCTGTAAAAAAGTCTGGTACATCGACTGGT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CCAGATAAGGTTTGATAGCAAAGGGGAGTTTAATCTT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AAGGCAAAATTCATATTATTCAACTCCGATGCTAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AACCTGTTACAGGTTATGCTAGATAGGTACTAGCAGT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATTCCATTAAAAGAAGCTGCCAAAAAACTGAACTAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TATTGTTGCAACTGTCTGGTATTGGGATAGAGATGAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTGTAGACGACATAATTGAGTCTCCAGACTTTTGGAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTTACAGGGAATCTTAAAAGAAATTCATAAAATCAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTTTTCTTAAATTAGAAATAGAATTTATAACATCTA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTTCAACAAAGGTTTTTTGTTCCGTTTCATTGTCA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TCTCGAACCGGTCAAGCGATCGCTAAAGAAAAACTTATTAAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	GTAGCTTACAAAAACATCTTAGGCAATATAAAAGCC
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTTTAAGGTGCAACGAGACTGGGTATATACCGTTGA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AGTGTTCCCTTTCCCTGGAACAACCAAGCCTATCAC
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTGAAGTTGTGCCAAACTTTTCCGAATCCGGCTATTT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TAGAGTCTTACATAGCCTCGAATTTTGTGTCTATAGATGA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATTCACTGGACAGATGCAACAGATTTTAAGGTTAAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTAGAAAATAGTAACGTTTTAAAGCCAGAAGAGGT


>NC_019772|2|2|31583-34510|CRISPRCasFinder
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATACGCGCTGCGAGTGCGGTATGTGTGGTAAGTGA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATAGACAAGAACTAGAACGTAAAGAGATTATCTGGAAAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTTACTCCTACTATTCCTTACTTTGTTTTTCCAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATAATTTAGATCCATTTATTTATCGTTGGAAATG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TCGATAGTGAATCGTGGGATATTTTTGTTCACAAGAAAC
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ACTGATATCCAGCAAGTCTCGTGGGCTTCATCACAAATAAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTGGCAAGACATCCTACAATATAGATACCTTTTGTTTTGTTG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTGGGCGTAGCTTCTGAGAAGCTAGAAATTCCTTCAGATGT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AAATTATTGCGATCGCGAAGGCAAGAAATATGAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CAATAACTGATATTCCTAAACTCCACAAATAAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TATTTGACCTTAGTGCCTGGTAAGTGGGGTGCAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTCTGAGCTTTTACAACTCCGGCCGCGATTAAAGG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TAAAAAAAATCATGGCTACCACACAAACTGCTCTTAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	GATATAACTTTAATGCTTTAATGTAGACGATACTCCTTT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AACTAAACTACCAGAATCTGTACTTATATCTAGGAGA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TCAATTTGATAGCTGCCAGGAATCGGACAAGGGGCAG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTCATTAAATTGTCGAGGTTCAGTTTTGATTGATAAAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CATCAACCTCAATTAAATTAAGGGTATCTTCAACTTTAAAAC
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTGATGAAAATCATAATTGCTGATAACCTGTGTAGGGAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	GGGGGCTAACTTATCTAGGGTTAGGTTTTTGGATCAATGCTAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTATCTCCAATCGAGTCTTATCAAATCTTGACTG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TATCTAGTCTGTAAAAAAGTCTGGTACATCGACTGGT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CCAGATAAGGTTTGATAGCAAAGGGGAGTTTAATCTT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AAGGCAAAATTCATATTATTCAACTCCGATGCTAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AACCTGTTACAGGTTATGCTAGATAGGTACTAGCAGT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATTCCATTAAAAGAAGCTGCCAAAAAACTGAACTAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TATTGTTGCAACTGTCTGGTATTGGGATAGAGATGAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTGTAGACGACATAATTGAGTCTCCAGACTTTTGGAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTTACAGGGAATCTTAAAAGAAATTCATAAAATCAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTTTTCTTAAATTAGAAATAGAATTTATAACATCTA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTTCAACAAAGGTTTTTTGTTCCGTTTCATTGTCA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TCTCGAACCGGTCAAGCGATCGCTAAAGAAAAACTTATTAAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	GTAGCTTACAAAAACATCTTAGGCAATATAAAAGCC
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTTTAAGGTGCAACGAGACTGGGTATATACCGTTGA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AGTGTTCCCTTTCCCTGGAACAACCAAGCCTATCAC
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTGAAGTTGTGCCAAACTTTTCCGAATCCGGCTATTT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TAGAGTCTTACATAGCCTCGAATTTTGTGTCTATAGATGA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATTCACTGGACAGATGCAACAGATTTTAAGGTTAAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTAGAAAATAGTAACGTTTTAAAGCCAGAAGAGGT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC

>NC_019772|2|1|31583-34510|CRT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATACGCGCTGCGAGTGCGGTATGTGTGGTAAGTGA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATAGACAAGAACTAGAACGTAAAGAGATTATCTGGAAAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTTACTCCTACTATTCCTTACTTTGTTTTTCCAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATAATTTAGATCCATTTATTTATCGTTGGAAATG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TCGATAGTGAATCGTGGGATATTTTTGTTCACAAGAAAC
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ACTGATATCCAGCAAGTCTCGTGGGCTTCATCACAAATAAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTGGCAAGACATCCTACAATATAGATACCTTTTGTTTTGTTG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTGGGCGTAGCTTCTGAGAAGCTAGAAATTCCTTCAGATGT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AAATTATTGCGATCGCGAAGGCAAGAAATATGAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CAATAACTGATATTCCTAAACTCCACAAATAAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TATTTGACCTTAGTGCCTGGTAAGTGGGGTGCAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTCTGAGCTTTTACAACTCCGGCCGCGATTAAAGG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TAAAAAAAATCATGGCTACCACACAAACTGCTCTTAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	GATATAACTTTAATGCTTTAATGTAGACGATACTCCTTT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AACTAAACTACCAGAATCTGTACTTATATCTAGGAGA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TCAATTTGATAGCTGCCAGGAATCGGACAAGGGGCAG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTCATTAAATTGTCGAGGTTCAGTTTTGATTGATAAAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CATCAACCTCAATTAAATTAAGGGTATCTTCAACTTTAAAAC
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTGATGAAAATCATAATTGCTGATAACCTGTGTAGGGAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	GGGGGCTAACTTATCTAGGGTTAGGTTTTTGGATCAATGCTAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTATCTCCAATCGAGTCTTATCAAATCTTGACTG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TATCTAGTCTGTAAAAAAGTCTGGTACATCGACTGGT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CCAGATAAGGTTTGATAGCAAAGGGGAGTTTAATCTT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AAGGCAAAATTCATATTATTCAACTCCGATGCTAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AACCTGTTACAGGTTATGCTAGATAGGTACTAGCAGT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATTCCATTAAAAGAAGCTGCCAAAAAACTGAACTAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TATTGTTGCAACTGTCTGGTATTGGGATAGAGATGAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTGTAGACGACATAATTGAGTCTCCAGACTTTTGGAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTTACAGGGAATCTTAAAAGAAATTCATAAAATCAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTTTTCTTAAATTAGAAATAGAATTTATAACATCTA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTTCAACAAAGGTTTTTTGTTCCGTTTCATTGTCA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TCTCGAACCGGTCAAGCGATCGCTAAAGAAAAACTTATTAAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	GTAGCTTACAAAAACATCTTAGGCAATATAAAAGCC
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTTTAAGGTGCAACGAGACTGGGTATATACCGTTGA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AGTGTTCCCTTTCCCTGGAACAACCAAGCCTATCAC
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTGAAGTTGTGCCAAACTTTTCCGAATCCGGCTATTT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TAGAGTCTTACATAGCCTCGAATTTTGTGTCTATAGATGA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATTCACTGGACAGATGCAACAGATTTTAAGGTTAAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTAGAAAATAGTAACGTTTTAAAGCCAGAAGAGGT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC

>NC_019772|2|2|32325-34510|PILER-CR
	ATACGCGCTGCGAGTGCGGTATGTGTGGTAAGTGA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATAGACAAGAACTAGAACGTAAAGAGATTATCTGGAAAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTTACTCCTACTATTCCTTACTTTGTTTTTCCAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATAATTTAGATCCATTTATTTATCGTTGGAAATG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TCGATAGTGAATCGTGGGATATTTTTGTTCACAAGAAAC
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ACTGATATCCAGCAAGTCTCGTGGGCTTCATCACAAATAAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTGGCAAGACATCCTACAATATAGATACCTTTTGTTTTGTTG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTGGGCGTAGCTTCTGAGAAGCTAGAAATTCCTTCAGATGT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACAAATTATTGCGATCGCGAAGGCAAGAAATATGAAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAACCAATAACTGATATTCCTAAACTCCACAAATAAAGTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TATTTGACCTTAGTGCCTGGTAAGTGGGGTGCAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTCTGAGCTTTTACAACTCCGGCCGCGATTAAAGG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TAAAAAAAATCATGGCTACCACACAAACTGCTCTTAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	GATATAACTTTAATGCTTTAATGTAGACGATACTCCTTT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AACTAAACTACCAGAATCTGTACTTATATCTAGGAGA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TCAATTTGATAGCTGCCAGGAATCGGACAAGGGGCAG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTCATTAAATTGTCGAGGTTCAGTTTTGATTGATAAAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CATCAACCTCAATTAAATTAAGGGTATCTTCAACTTTAAAAC
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTGATGAAAATCATAATTGCTGATAACCTGTGTAGGGAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	GGGGGCTAACTTATCTAGGGTTAGGTTTTTGGATCAATGCTAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTATCTCCAATCGAGTCTTATCAAATCTTGACTG
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TATCTAGTCTGTAAAAAAGTCTGGTACATCGACTGGT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CCAGATAAGGTTTGATAGCAAAGGGGAGTTTAATCTT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AAGGCAAAATTCATATTATTCAACTCCGATGCTAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AACCTGTTACAGGTTATGCTAGATAGGTACTAGCAGT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATTCCATTAAAAGAAGCTGCCAAAAAACTGAACTAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TATTGTTGCAACTGTCTGGTATTGGGATAGAGATGAA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTGTAGACGACATAATTGAGTCTCCAGACTTTTGGAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTTACAGGGAATCTTAAAAGAAATTCATAAAATCAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTTTTCTTAAATTAGAAATAGAATTTATAACATCTA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTTCAACAAAGGTTTTTTGTTCCGTTTCATTGTCA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TCTCGAACCGGTCAAGCGATCGCTAAAGAAAAACTTATTAAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	GTAGCTTACAAAAACATCTTAGGCAATATAAAAGCC
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTTTAAGGTGCAACGAGACTGGGTATATACCGTTGA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	AGTGTTCCCTTTCCCTGGAACAACCAAGCCTATCAC
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TTGAAGTTGTGCCAAACTTTTCCGAATCCGGCTATTT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	TAGAGTCTTACATAGCCTCGAATTTTGTGTCTATAGATGA
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	ATTCACTGGACAGATGCAACAGATTTTAAGGTTAAT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	CTAGAAAATAGTAACGTTTTAAAGCCAGAAGAGGT
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019772.1\|WP_015217575.1\|37308_38595_+\|DUF1887-family-protein	csx1	mkCas0112_csx1_CAS-III	gnl\|CDD\|312526
NC_019772.1\|WP_081593763.1\|47320_47944_+\|DEAD/DEAH-box-helicase	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_019772.1\|WP_015217571.1\|29020_29683_+\|acetoacetate-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|377649
NC_019772.1\|WP_015217574.1\|35764_37192_-\|TIGR03985-family-CRISPR-associated-protein	WYL	mkCas0075_WYL_CAS-I:CAS-III	gnl\|CDD\|274901
NC_019772.1\|WP_042466305.1\|27284_28658_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|350691
NC_019772.1\|WP_015217568.1\|24297_24921_+\|Uma2-family-endonuclease	unknown	unknown	gnl\|CDD\|368559
NC_019772.1\|WP_015217573.1\|30408_31539_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl\|CDD\|227838
NC_019772.1\|WP_015217579.1\|42567_44112_+\|DUF324-domain-containing-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|274211
NC_019772.1\|WP_015217582.1\|50024_50972_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217567.1\|22590_24090_-\|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl\|CDD\|237862
NC_019772.1\|WP_015217577.1\|40239_40932_+\|hypothetical-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187857
NC_019772.1\|WP_150111126.1\|25342_26803_-\|DNA-polymerase-III-subunit-beta	unknown	unknown	gnl\|CDD\|238082
NC_019772.1\|WP_015217576.1\|38603_40277_+\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl\|CDD\|187811
NC_019772.1\|WP_015217580.1\|44108_44714_+\|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	gnl\|CDD\|274900
NC_019772.1\|WP_015217565.1\|19738_21331_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197231
NC_019772.1\|WP_015217564.1\|16268_19742_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NC_019772.1\|WP_015217572.1\|30163_30358_+\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217578.1\|40928_42575_+\|DUF324-domain-containing-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	gnl\|CDD\|131722
NC_019772.1\|WP_015217566.1\|21598_22594_-\|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl\|CDD\|180982
NC_019772.1\|WP_081593764.1\|47924_49964_+\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124

Protein	Function_ID	Function_description	E-value
NC_019772.1\|WP_015217575.1\|37308_38595_+\|DUF1887-family-protein	gnl\|CDD\|312526	pfam09002, DUF1887, Domain of unknown function (DUF1887). This domain is found in a set of hypothetical bacterial proteins.	3.36009e-06
NC_019772.1\|WP_081593763.1\|47320_47944_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.17934e-23
NC_019772.1\|WP_015217571.1\|29020_29683_+\|acetoacetate-decarboxylase-family-protein	gnl\|CDD\|377649	pfam06314, ADC, Acetoacetate decarboxylase (ADC). This family consists of several acetoacetate decarboxylase (ADC) proteins (EC:4.1.1.4).	3.48568e-19
NC_019772.1\|WP_015217574.1\|35764_37192_-\|TIGR03985-family-CRISPR-associated-protein	gnl\|CDD\|274901	TIGR03985, hypothetical_protein_sll7078, CRISPR-associated protein, TIGR03985 family. Members of this protein family belong to CRISPR-associated (Cas) gene clusters. The majority of members are Cyanobacterial.	3.60946e-85
NC_019772.1\|WP_042466305.1\|27284_28658_-\|AAA-family-ATPase	gnl\|CDD\|350691	cd17933, DEXSc_RecD-like, DEXS-box helicase domain of RecD and similar proteins. RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	8.09485e-28
NC_019772.1\|WP_015217568.1\|24297_24921_+\|Uma2-family-endonuclease	gnl\|CDD\|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	7.61361e-27
NC_019772.1\|WP_015217573.1\|30408_31539_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.45556e-52
NC_019772.1\|WP_015217579.1\|42567_44112_+\|DUF324-domain-containing-protein	gnl\|CDD\|274211	TIGR02581, putative_CRISPR-associated_protein, CRISPR-associated RAMP protein, SSO1426 family. Members of this CRISPR-associated (cas) gene family are found in the RAMP-2 subtype of CRISPR/cas locus and designated TM1809 family.	6.10563e-17
NC_019772.1\|WP_015217567.1\|22590_24090_-\|DNA-polymerase-III-subunit-gamma/tau	gnl\|CDD\|237862	PRK14948, PRK14948, DNA polymerase III subunit gamma/tau.	2.18346e-152
NC_019772.1\|WP_015217577.1\|40239_40932_+\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	1.17989e-06
NC_019772.1\|WP_150111126.1\|25342_26803_-\|DNA-polymerase-III-subunit-beta	gnl\|CDD\|238082	cd00140, beta_clamp, Beta clamp domain. The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria. The beta-clamp is structurally similar to the trimeric ring formed by PCNA (found in eukaryotes and archaea) and the processivity factor (found in bacteriophages T4 and RB69). This structural correspondence further substantiates the mechanistic connection between eukaryotic and prokaryotic DNA replication that has been suggested on biochemical grounds. .	2.85953e-74
NC_019772.1\|WP_015217576.1\|38603_40277_+\|hypothetical-protein	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	9.25225e-07
NC_019772.1\|WP_015217580.1\|44108_44714_+\|TIGR03984-family-CRISPR-associated-protein	gnl\|CDD\|274900	TIGR03984, hypothetical_protein_FrEUN1fDRAFT_5778, CRISPR-associated protein, TIGR03984 family. Members of this protein family are found exclusively in CRISPR-containing organisms, in operon contexts with RAMP (repeat-associated mystery protein) proteins also linked to CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats).	1.62986e-32
NC_019772.1\|WP_015217565.1\|19738_21331_+\|hypothetical-protein	gnl\|CDD\|197231	cd09133, PLDc_unchar5, Putative catalytic domain of uncharacterized hypothetical proteins with one or two copies of the HKD motif. Putative catalytic domain of uncharacterized hypothetical proteins with similarity to phospholipase D (PLD, EC 3.1.4.4). PLD enzymes hydrolyze phospholipid phosphodiester bonds to yield phosphatidic acid and a free polar head group. They can also catalyze transphosphatidylation of phospholipids to acceptor alcohols. Members of this subfamily contain one or two copies of the HKD motif (H-x-K-x(4)-D, where x represents any amino acid residue) that characterizes the PLD superfamily.	7.99391e-27
NC_019772.1\|WP_015217564.1\|16268_19742_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	8.13893e-46
NC_019772.1\|WP_015217578.1\|40928_42575_+\|DUF324-domain-containing-protein	gnl\|CDD\|131722	TIGR02674, cas_cyan_RAMP_2, CRISPR-associated RAMP protein, Csx10 family. CRISPR is a widespread repeat family in prokaryotes. At least 45 different protein families occur in prokaryotes only when these repeats are present. This family, a minor CRISPR-associated protein family, seems largely restricted to the Cyanobacteria. It belongs to the RAMP superfamily (pfam03787).	1.14688e-49
NC_019772.1\|WP_015217566.1\|21598_22594_-\|DNA-polymerase-III-subunit-delta	gnl\|CDD\|180982	PRK07452, PRK07452, DNA polymerase III subunit delta; Validated.	3.94155e-77
NC_019772.1\|WP_081593764.1\|47924_49964_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	8.83549e-28

>NC_019772.1|WP_015217573.1|30408_31539_-|CRISPR-associated-endoribonuclease-Cas6
MPRVATSSKRKTPSQNTSLVWADDTELVGLVFDLEVTNSTSLYSQYTIGLHAWFLDQVRQINPTLSAYLHDGESEKPFNISALEGQLVPTGKQLQLQANHIYRWHLNAISQPVVQFLSQWLNQPPTILTLRDASLQIKQISIVHPPNTYSLLLQSSTGKHTNINLSFISPTSFRRKGHHFPLPVPVNLFHSYLRRWNDFSGMPIEQDAFLNWIDENVIIHKHSLESVKVAAGKRGSVTGFTGVISLGLSKSALANIEFTQLFYALIQLAPYCGTGHKTTFGLGQTCLDWVEPESNTSSGMLTNLLPERIEELTAIFTAQRKRTGGDRTEKIATTWATILARREMGESLQVIAQDLEIPYTTAKTYVKLARRTLKDT
>NC_019772.1|WP_015217572.1|30163_30358_+|hypothetical-protein
MSTTKVHLLISINDLVLLVFYSESDCWQFRLISSGCEVLFGERKLYYTPEAAEKAGREWVYQGY
>NC_019772.1|WP_015217571.1|29020_29683_+|acetoacetate-decarboxylase-family-protein
MTYPTAPWKLEGYAIQTLHLVDIKQAVPFVPSELEIVSFLPGKTLAGTYISSYEAGSLLEYNELIVVPAFVRYQGYIGAWISHIYVDNEDSVAGGREIWGLPKELAEFSGDNHGKVSVKQNQRELYQLSYKKDFLSLSTWWQQEFKGNAFGGLGSELLYFQNNFKSQISLLKANLEIPQHSPFASLSLGQPWLTLNLQKLELVAGVPKLLGNEVINLSYS
>NC_019772.1|WP_042466305.1|27284_28658_-|AAA-family-ATPase
MLQTLPTFLTTNSFPFQFTQQQQKALDKMWTFIQPTVTAALFLLVGFAGTGKSTIIFQLVKVLVATGKRVVLTAPTNKAVGVLQRMAAENGVTGVEFFTIHQLLGLGMVTRGKEKILDQIGPCYINLFDVVFIDECSMIGKQLWHWIENVANQSSTWTKIKIILMGDPAQLNPVNERKSPSFQVANKAVLTQVVRQGIDSPLLEFVTASRYAVTKSKLPFAPFSKYLPDKSNGALIVKRQTLLRYAYKKISQKFAHNPDCFRILSWTNAQVDFYNQQIRRYLYGENANRFISGERLITKDPIMAPDGKTAILSTSTEFTVLDVLEDRYNNYDSWRLKVETDEGIVRQIYVLHEDEEKRFHQETQRLLKSAKRNPFLWKQYYKHLEQFANIRNCFALTVHNSQGSTFLEAGIDGQDLSKRLNRERGDDSKAVLAKIKEFNRLYYVSSSRARQRILVIR
>NC_019772.1|WP_150111126.1|25342_26803_-|DNA-polymerase-III-subunit-beta
MIMTQTAPKQKVNSTKQTKQTSVATPEIDNEVSTNITEIPGVKKKKSTSANSETPTEPIQKKGNKRKKSKSKLNPPIPKELGMEVICEQTKFYNALFLVNCATPAKPSHPILANVLIIADVETQQIHLTVTDIALTIQASFAAQVLLKGEITVPVAMLLEIVKHCPSDNISLNSQTQMTQMTDENKPTKIYSLCLSDADGKYEIRGISAEEFPPTNIIDATPISLPTTVFKDGLKGVLYAVSTDENKYIVTGVHIQFAQEKLKFIGTDGHRVAITEVSTQGIGRKPRQQVTSEEMIKFTLPGRVVREIARNLGDDVKSISMLYNSQSNRLEFAWQDVVLSCQILEGIYPDCEQLLTKFSFEKEVILEKAPLVKALERLSVLTDKKEKGIYLQFDGSLQQLRLSIEREFGKGDQVIVANLPSEMMLNIQFNLKYLIEAAKAIPGTSIKMHLQQSDHPAMLVPDGDRPNPEVEMSMRHFLLPLYTPQQ
>NC_019772.1|WP_015217568.1|24297_24921_+|Uma2-family-endonuclease
MVQALLKTKSLTFEEFIACKPEGNCYELHNGVIIEMNQPVGKHEDIICFLNEKITAEYLRLNLPYGIPKTALVKPSESESAYSPDVLVLNRPNLVNEPLWEKESTVTQAASISLLIEVVSTNWRVDYLTKAGDYEEMGIPEYWIADYLGLGGRRFIGSPKQPIISVHELIDGEYQVSQFRGSDRIISPTFPELSLTANQIFQAQWLI
>NC_019772.1|WP_015217567.1|22590_24090_-|DNA-polymerase-III-subunit-gamma/tau
MSTVALHQKYRPQTLAELVGQPYIKTALTNAIKHLQIAPAYLLTGSRGTGKTSTARIFAKSLNCLNSKKPTDKPCGICQSCRAIETSNSLDVSEIDAASNNGVDDARALIERCTLAPVAGRYRIFILDENHQLTTQSQNALLKCIEEPPPHVIFILCTTEQHKVLPTIISRCQVFNFRTLSIKTIVQHLRIIADAESIAVDDEALSAIARLSDGGLRDALQLLGQASLLDVDITAHHVMEIVGGVTEAELIAILQAISTNNTFNLLQVARVLVDSGKTPKLIISNLLQTYRDLLIIKSAPQEQALLTGCVSHTQLKAFAKHWNFETLNLSLGELQKAENYLRYTVNATVWLEVCLLNLLPGLLPGGATKTVNVKPGHDGKLLPTYGTYTINKVTDKPVDDPGKDSLLPAVATNTANLAQIWQQVMDKAKPNHQKLLAHASLVKLQGSKAILEVTPAYQKKFENGKDAIAKMLERATQSPKPLTVLIKTANLNNNGRVTG
>NC_019772.1|WP_015217566.1|21598_22594_-|DNA-polymerase-III-subunit-delta
MIVLLTGDDEYAIQSQLNQYKAEIDAQWLTLCYHRFPAVQLDKALSVARTRSLTGGKKLVIVENCHLKQWGDPELETLQQLVQVPKSTILVFVANNVDKRLKVYKHLVKYGKLLEFSLIPPWRYDLIEQAIVSLAARLYTNTTDNAVTPKKIKLVLSEEAVTYLAQAIGNDMTRAASELRKLSIYAQGRKLELAEVQELVPCQTQNSLQLAAAMREGKSHQVLQLLDDLLSRCQPLMVIVSTILTQFRTWLWVKSAIVSGVKKDGELAQLCNISNPRRVYYLRQEVANTSINALAKAVTMILDLEMSIKRGADGRDLLVVILGVCRLFQVV
>NC_019772.1|WP_015217565.1|19738_21331_+|hypothetical-protein
MILDELDTQNTNDTDEIARRYDNRPGFELVSVVEVGLPVTKINLTALTLVRKPIPPIEEFILKAINIGLSSLEEISYFLGLEELIIKDSIINLRQAENIDLIASLGSSIQEWKLTKKGKTTLEEARIITPEERGYQINFDKMLWKPRRYGSWEDNKSLLRHKNLKNNNIVEIPYYPARTPELADLNLKDVEKIIQEKENEKDGRRKKEEERDFKRDFIGLKKIERRDNFFQPALALVYKQKQGNDWQITFAIDGRISEVHESAFTRSKGPKKDRIIKELKESFSTQIRYAKILAKEKFGDEFLTLAIEYEKQIDSVREEINNRSNIIQTDIDSTRQTLEKVNDDEQKVALEEKLNNALEEIKQLQEQLEQLISSTPIRFIKTYDHRPLFEEALKNSQKRLLIISPWIRATATNQWLVNQLEKLVRRGVKVFIGYGYGDKDEKDRRDYDIKAEEAIQKLAKRYPDNVVFKRLGDTHCKILISDQRFAIVGSFNWLSFKGDPNRTFRDERSTLVSDPNKIDELFNDEITRLI
>NC_019772.1|WP_015217564.1|16268_19742_+|protein-kinase
MKARLLNGIYTLMPNPKSGGMAKIYKARDINNDNLVAVKIFENGQIEQEITDESFRREVSALKELKHPRIVQLIDSGLDEETGHNFLVLEWMESNLATSLKESPLAGWDEFWERVGLPLLEALAFSHNRECIHRDIKPNNILINTEGIIKLADFGISKVKRYLQPTVTLREFVSRPYSPPEEDDGSYTYTRDVFSFGVLILKCLTEVELITYDTIKQAIKQFDASPEIITIIERSVSLEPSERQHNAEVLLVEIQAIQEKRKKEYQVKQGSCYLKLPSRIDKIADELEADSNNEIEKIILQDLNSGCAMCRFEKRNPVDREDKYEENQYKIFGTDYSYHVKIDDRDQEKLVILNVMNLSSSILEENRNRYWHPPYNFKFGNSSNRLEDKTVISKLKLLIEEYESEIRQKQAEEEKQRLFRNWENILRAKTDWEKEHQPPLNYIEVTRQENRAIFTLASITDENLVEQPRLVIVNNRTLLSGNVEEVKEDKLTLYINSGDPERLPKSGELRFDTRAAEYALRQQKNALEAIKYDRAARSDIRSLLITPQEVKTPTTEENIKFIQSLNQSQKETVEAALGTQDFLVVEGPPGTGKTTFITEVILQTIRANPQARILLTSQTHVALDNALERIKKQNPALKMVRIGNHEKVADNIHDLLLEEQMEHWKSEVFRRSQGFLENWSKKHNLSPQEITMANLFQKLREALMELDRLKKEIEIFQQEQYEITQTEELKAYFENYNLNDLRSEIHKNLPDDINREWEFINDKIKGLENKTKEIRDQRKDTVKELHQVSQIDEEELLKMSLSELEGYENILIDLNQPEAKKLRTLMKVQQDWFDIFGRADSDRFNTAFLKQAQLVAGTCIGLARSIPEIEFDLCIIDEASKATATEVLVPIARSHRLILVGDTKQLPPFQDEASRNFDFLNKYNLDSEEIKETLFAYLIKTLPDSNRKILTIQHRMVAPIGNLISECFYQGQIESARDDLDNDLTQVIPKPVTWFTTSKLPDCREQAANGSYNNMAEVNVILKILEQINKMAITVNKKYGIAVLTGYSAQLKLFKRKLDSELSNWEALTIKYNTVDAFQGQEADIAIYSITRSNKKASLGFLRDTERMNVALSRGKVGLIIVGDHNFCRSLNYNPLHTVLNHIESHPESCSLFEVKS
>NC_019772.1|WP_015217574.1|35764_37192_-|TIGR03985-family-CRISPR-associated-protein
MNILFTTTPSPNILQQLANGSLDQGHNLTRAIRLWVLLHWLYSDQGQAAIGDTFTYTDWRQAFFTKTHKDEKQTDIINHQDPDCACLKTTRQWLVELEVSIDEWQNSLQQHIPVYNSDLEKLVEEILKERLFAQVRKSLQSDLDLLVSKNCLQRVDNVPGRSKYYRRVDVLPLSTTSDNCGYETSLSNKKQAYLAGTLGMFSFLDPSLPLLAEEISEEEIDEDNHRVFLYADYVVPESSPIQDAVDEIQSDLQDIWDSGKIQPLLLTYHSAHQNQIYECVVYPVCIYFMERAKYLCAYGKTPKGDINWYKYRLDRIISQRLEILDWEDNRIPQLLRDKYKENQLPTPKTVNMKLKDAWGCDFYKEKTLMILRFEKNFHQNYIQGINIHQTFRAINYEKAKILIRQNTPNSLHQHILPILDSRSNHDAYYQVYYRNTDYYVIRWLRALGSKVEVLLPWELRQEMLLELQNTWNLYK
>NC_019772.1|WP_015217575.1|37308_38595_+|DUF1887-family-protein
MSISELDKYKVDHLFLLIGENPLPNYITAQILLKDGGTVYLVHSTDTTSKAASLERMLKAVNVKPISLGRQEANSCVIQDKIQTEVKNILKKHPNHTFGLNYTGGTKAMSVHSYRALFDISEVSNPVFSYLDARSLQMLIEREDDTPKSEIIKIQVKLEELFNLHELPWKKNKRPNPKPVLHDAAQEFLNAYLSVTPRNTDNTAEQWWKWCKTQLHPQTKDKYGFWYPETELMKISGITLDGAPENIKNILHQYQMLNSKGELDMQASKNQGFGELSDFCAWLSGVWLEHYVLHQIKNISANFLSIHESAMSFHIDDPNNRDDRYDRFEFDVAFMRDYQLFALSCTTAGDKSTCKQKLFEAHLRARQLGGDEARVGLVCFHNNPERVKRDLEATIRDKKIVVFGSPDLKPDKFVKKMQQWIHDNSPIL
>NC_019772.1|WP_015217576.1|38603_40277_+|hypothetical-protein
MSKYIATVIDTTGIQPYIFGSNRLRENIGASYLVEQATNGWVKCALRQIFGENVYIPEPEQEEKCIEHDNLDAELVYTGGGNAVILFKGREDKKSAIRFTKRLSKRVLQEAPGLKIVVAHSEPFEWGNKLSGIVDSLMKKLERKKREYNPSVPLLGLGVTANCLSTGLSAVDTSDRYSVPTSYPVSREIVEKLRAVDPKNKAPANQELNDTIFKNLPLGNYIVPYDIDDLGRTEGKISYMAIVHADGNGMGDRFKEHGRKCKTDREYITAMRELSKTVNQAGVNALKKVAQRVIHLADGKLQEQFAITERNGEKYLPFRPIVYGGDDVTFVCDGRLGLSLAALYLKEFEAQKVADGKDLTACVGIAIVKTHYPFARAYQLSESLCKKAKNFVRSEKEELKILDFSALDWHIAPSGLLGSISDIRQREYQVAEGNLTMRPLYLHSDSDWRNWDDFSEVVNKFNTDSDWSRNKVIALREQLRQGSEKTKQFLQVYGLNENYLPQFGKAKSDDLYQSGWIDHRTNTKVCGYFDAIEAMEFHIPLKEKSDGDLLSENATFE
>NC_019772.1|WP_015217577.1|40239_40932_+|hypothetical-protein
MEIYYLKMLLLSDTTFGRGDGVAGLIDQEVEHDANGFPYLRGRTLKGLLSEECDNLIAVLSEPPPSRWQKAAEHLFGIPGSTLETISKMHVGDACLPQDLRKAVKLQLDQEQQRESRGQERRFTEVDVLTSLTTIRRQTAIDPEDGAPVEHSLRSSRVILRDLCFTAPLLFEKKPAADMLALLAVSILALQRVGSGRNRGRGHVRCTLHDSIGEEITQEHFRYFEQETRK
>NC_019772.1|WP_015217578.1|40928_42575_+|DUF324-domain-containing-protein
MKAITFLLHTKQPLLATSLQGDPNSDVSFPYIPGSMIRGVLISRYLQRHSLKSTDDILDESKYPDIKRLFFNGNTRYLNAYLYDTEKQNRTLPVPCSWLKKKGDEISDSDDTTVYDFSYESPEEDISYKSLDEGFCTVNDQDVLLYKEKRRINIHNMRNRKKGRGDEGKGAIFRYEALDAEQYFQAVILCDNPDDIEKIKPLLEPQEMWLGGSQSAGYGHTQIIPIEEDEEYDYWDEVGIEAEDRNDRELIRITLLSDLILRDKWGHYVATPPNSTGDEINQKVESLTQILEELLDIKLEPQSSYTSSLIVGGFNRKWGLPLPQVPALAAGSVFVFKYNKQDGELDSEKIRLVENQGIGERRVDGFGRITINWLEEEAIFNACLPKRETNWDKPQLVPNSEDSQLAQKMAKRLLEQKLDSLILKKLNNSNCKLEPNRLSHSQLSRLMIVCRQALNEENKNPVIKLLENLPKNANRQFEGTKINHKQSFKTQIYEWLNNPNTWIDSSYLEVKVAGESVLLDLVEKLKLEYTLRLIIAVAKQAVKDKQDE
>NC_019772.1|WP_015217579.1|42567_44112_+|DUF324-domain-containing-protein
MNREREGRHIIKRIIVRGVLVLDTPTCLGSGDAEGTTDMMLLLDSISDNPLLTGSSIAGALRNYLHEYECDYAKNESRDNIAAKLFGDLFAYKDERNKNEAEKIALREKDTQSPLIIHDAIGSTIHNVEIRDGVKIDGATGTASDKAKYDLELLPAGTKFSLNFELLIEKDKDENELKQALALALEGLKNGEIAIGMKKRRGFGRCHVDEWQVWEFDLTKHSERIAWLTFERPWGKPYATKLPSDKLLSNTHLQKLKVDKPDKRDRLFITAKFQLASPLLIRSGQYLIQNKCSPDVVHLHSYRKDKPEPVVSGTSLAGVLWHRAERIVNTLDKNLQIVYDLFGFVKEESKQAKASRLVIHESLIENTDEIVQSRIAIDRFTGGAYNGALFQEQPVFGISKKEDNQKNNKVKGKSTKSSNTSNHTAHIKLELELRQPKEYEIGLLLLLLKDLWTGDLPIGGTSSIGRGRLQGVEATIVWQQHKWLISEENQKLLVSKQEKEQMEEVVKKFLEQAP
>NC_019772.1|WP_015217580.1|44108_44714_+|TIGR03984-family-CRISPR-associated-protein
MNQDLCQELSTETIEKSLENWLKQQAITQDYQLCYVLAHAEDGVIWGNFEVESGILKTSNQAFPEYDFPALRLSTLQQCRIFGEAGEILLWNSNSTWRSRLILQSQVSELLKQEKIGLIPESQILWGTQGKENGNFTLLSDGSQGLKYAAPITGMTVSQDKQKQYRPLRLEVHHYFCYDQDGVARIFLSRLVSLKEKIYES
>NC_019772.1|WP_081593763.1|47320_47944_+|DEAD/DEAH-box-helicase
MIDAHFQTLTTFPPRNFQREAIAKLLHRQNILLRAPTGSGKTETAIAPFLFAKTLNLDFPNKLIYVVPLRTLANSLRQRTETLVQRWSQTQNIPCPVVTLQTGENPEDPRFEGDIVFCTIDQMLSSFLNIPYSVGRGSANVNSGAIFASYLVFDELHLLDPDRSFTTVLKVLQQVKGISPFLLMTATLTNELATQIQGLIDNGNNSN
>NC_019772.1|WP_081593764.1|47924_49964_+|CRISPR-associated-helicase-Cas3'
MEIIQIEDTDLQAIEGKRRRIFQAKSHPLNALEIIADIHTNQRKRVIIICNTVSQAQGLYRDLRELNHDETLNLTLLHSRFLPEHRAQKETFLKETFAENWQDDGTCYVLISTQVIEAGINITCQVMHSQLCPMNSLLQRAGRCARFQDEQGQVLVYRTIEVNQAYSTLAEADLEPETESTDKKQSFLPYPRETCESTWQVLQTHTESNQVNENVGFRTEENWINQVHTTEDLLQQQRRQNNQMQFEQHFEAAFFRGDQSFASELIRSVDSRSLFVWEETGFIDFEEEPIDPRKLMAFSVPVSTLCKVWRDSKNLEFGTDWIFKRIEAPKDKAETYSQPVCTEIKSRDSLINSIKILVNPRFIYYDENIGLLIGINEFGNGFISPPKPQRTIASEYRYNMDTYIGHLGCMWTCWHKPFKTLRLKNGEAESTIYNSIRNELLPAGTKLIKNKIFPHIQESEAAALFEILVFFAIFTHDLGKLQIKWQQVMRGWQAIAHSSFHGQNPKQHLLAHTDYNPDDKDQKTALKDHEKKHKRPNHAVESAFLARDILKQSLVPVLRDYFEADNEQIQYICHTVIMAAGRHHSAWAGGWSIADITKIKTIELHPEAQRAIAQSWQSMTRFLSQILPLTPANLSKSIYPIKKEFDLNQLNTADEFEYFHLYLLVVRALRLCDQRSVQL
>NC_019772.1|WP_015217582.1|50024_50972_-|hypothetical-protein
MSEVKADYDGAWKEGVEKYFEAFLTFFFPQIYSEIDWTRGYEFLDQELQQLMRESEVGKQFVDKLIKVWLNDGKETWLIIHLEIQSQVDTGFPKRMFSYHYRIFDRYGQEVVSLAILGDNQASWRPQEYSYERWGCRLSLQFPTVKLLDYQPRWSELEQSDNPFAVLVMAHLRTQATTKNLTGRLQWKLSLVKRMYELGYSREKILQLFDLIDRLMTLPPDLDLNFKTELKQFEDDKKMAYITSIERLGIAQTLQKSIVKIIKTRFQDAPSQLVEQINKIYDHERLNQLLEQAITIGSVPDFQELLTQENTGTDS

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Crispr_ID: NC_019772_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019772_3

57672-61179

A:N

Consensus_repeat	Method
GTTTCAGTCCCCTTGCGGGGATTAGTTATATCGAAAC	PILER-CR
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	CRISPRCasFinder
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	CRT

47 spacers

cas2,cas1,cas4,cas6,cas5,cas7,cas3,csx19

The CRISPR arrays of NC_019772_3

>merge|NC_019772|3|57672-61179|PILER-CR,CRISPRCasFinder,CRT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACAATCAAATTCAGCTACGTACTTCGCGAAGCTTTCTAAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTCTTATCGTCTTGTTCTGCGGTTAGACCGATGCTGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACGCTACAATCACACAGAAAAAATTTTTATTGACCTAAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACATTAGATCAGAATATTCATCTGTGGCAGATGAGCCAAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACGTTTCACCACTGCTACCAGACCAACTACCTTTTTTCTTGGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACAAGCGTAAATATTTCCCGTATGAATTGGGGTAGGGTTTCGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACAAGACAATGCAGGAATTAAAAGGATACACACCAACAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACGCTTTGTCTATAGTTTATAAGGGTTAGAGTGATCCAAAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACAATTCTTCTTGTTTCTGGATGTTATAGAATTTAGATGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACCTCTTTTTATCAATCTTCCTCTGTAATCTTTTGATGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACGTTCTGGAGGAGGAGGATCAGGGGGTGATGCGAGTGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTCAACGCATATGGCGCGCAAGGTACAAGTTTCTGGACGAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTTCAGTTGGAATACAACAATAGGCGAAGTCCAGCTTTAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTATCTTACTATAGATACGACTATAGATAGTGATATAGGGGGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTCAATCAAGTACAATGGTGGCAATATCTCTTAAATGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACACCCTCGCTGTCTGGCAATTCTACTAGATGAGCTATGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTAGTCAGGTAGCTGCTGATTACCGTTTTGTGCGTAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACATCCTACTAACCGATGGCGAAGATCTCAACATAAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACGTTAAATCTCTGATTCCAAGCTCTCTGTTATTCGCTGCTATAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTAATATCTGGGGGATTGAGTGCGATCGCCAAATAGCAGGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACAGGAATTTAACTCATTTTGTAGGTTAGTTTCTTCAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTCTTCCAAAAATCAAAAGATATTCTTGCTGACAAGCAATCAATGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTACACTAAAAAAATAATCCCCCAAACCGTCGTAACCGGGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACGAGAAAATGACAGAAGAACAAGCAAAAGAACTTTTAATGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTTGGCGTAAATGTAGCCTATTAAATCCCCCTCAAGCGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACAACAATGGTTCGGGTTTCTCTATGTCTTGACCCTTGCCGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACATATCGTTATATAGTAATACGCGAGGATAGCGATATAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACGCCAATTTCAGAAAGATTGCCAACAAATGATTTAAGAAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTTAAAATCAGCCATGATCTTTAATAATTAAATTTAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACATTTCTTCCAGGGTTGGTTTATGGTGGAAAACCCTGGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACCAGAGAATCCAAACATCTTTAGAATCACCGCCAACCGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACAAAAGCTTGTTGTTTGTCAAGATGAATGTCGCAGAAAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTAAATGTACTATGCTGCTCTGGCATTTAAAATAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTTAAGAATATGACTAATTATTGCAATACAGGTGAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACCAACTATCGAAGCGGTTTCTTTCTGCTAAGTCCAATGGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACCAAACAGCCATAGACAACACTATTGCCACCGTTGGCGGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACGAGATACAAAGCAATCTGAGAAGTCTTTGCCACCTATAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTAATAAGCTTCCTTTATCGATCTAAAAGCTTCAGTAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTAACATAAACCCATAACCCTTGTCAAGCATGACTTGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTTCTTGCCATATCTGCAATAGCATTAGCAATCAAGAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACACAATACTCGCAGACTTAGAAGATTTTTCAAGCCTAGCGGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACAAAAGTTAGTTGCTAAAGAAGTTGGTGCGGCTGTCGGGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACATGCTATCCTATTAATTGCCTTATCAAAATAGTAGTGATTGGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACAATGTAAAATAGACAACATGAATCCATCATTGTAGGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACATTATCTATCTAATTGATTATGTTGTATGTAACTAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACTCAATCAAGTCCCAACATAAAGGCACTAGTTATCAAAAGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAACAATCCAATTAAGAACAGAAATAAATAACTCATCTTGTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC

>NC_019772|3|3|57672-61179|PILER-CR
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AATCAAATTCAGCTACGTACTTCGCGAAGCTTTCTAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TCTTATCGTCTTGTTCTGCGGTTAGACCGATGCT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GCTACAATCACACAGAAAAAATTTTTATTGACCTAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATTAGATCAGAATATTCATCTGTGGCAGATGAGCCAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GTTTCACCACTGCTACCAGACCAACTACCTTTTTTCTTG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AAGCGTAAATATTTCCCGTATGAATTGGGGTAGGGTTTC
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AAGACAATGCAGGAATTAAAAGGATACACACCAACA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GCTTTGTCTATAGTTTATAAGGGTTAGAGTGATCCAAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AATTCTTCTTGTTTCTGGATGTTATAGAATTTAGAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	CTCTTTTTATCAATCTTCCTCTGTAATCTTTTGAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GTTCTGGAGGAGGAGGATCAGGGGGTGATGCGAGT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TCAACGCATATGGCGCGCAAGGTACAAGTTTCTGGACGA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TTCAGTTGGAATACAACAATAGGCGAAGTCCAGCTTTA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TATCTTACTATAGATACGACTATAGATAGTGATATAGGGG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TCAATCAAGTACAATGGTGGCAATATCTCTTAAAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ACCCTCGCTGTCTGGCAATTCTACTAGATGAGCTAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TAGTCAGGTAGCTGCTGATTACCGTTTTGTGCGTA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATCCTACTAACCGATGGCGAAGATCTCAACATAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GTTAAATCTCTGATTCCAAGCTCTCTGTTATTCGCTGCTATA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TAATATCTGGGGGATTGAGTGCGATCGCCAAATAGCAG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AGGAATTTAACTCATTTTGTAGGTTAGTTTCTTCA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TCTTCCAAAAATCAAAAGATATTCTTGCTGACAAGCAATCAAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TACACTAAAAAAATAATCCCCCAAACCGTCGTAACCGG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GAGAAAATGACAGAAGAACAAGCAAAAGAACTTTTAAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TTGGCGTAAATGTAGCCTATTAAATCCCCCTCAAGC
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AACAATGGTTCGGGTTTCTCTATGTCTTGACCCTTGCC
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATATCGTTATATAGTAATACGCGAGGATAGCGATATA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GCCAATTTCAGAAAGATTGCCAACAAATGATTTAAGAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TTAAAATCAGCCATGATCTTTAATAATTAAATTTA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATTTCTTCCAGGGTTGGTTTATGGTGGAAAACCCTG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	CAGAGAATCCAAACATCTTTAGAATCACCGCCAACC
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AAAAGCTTGTTGTTTGTCAAGATGAATGTCGCAGAAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TAAATGTACTATGCTGCTCTGGCATTTAAAATA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TTAAGAATATGACTAATTATTGCAATACAGGTGA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	CAACTATCGAAGCGGTTTCTTTCTGCTAAGTCCAATG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	CAAACAGCCATAGACAACACTATTGCCACCGTTGGCG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GAGATACAAAGCAATCTGAGAAGTCTTTGCCACCTATA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TAATAAGCTTCCTTTATCGATCTAAAAGCTTCAGTA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TAACATAAACCCATAACCCTTGTCAAGCATGACTT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TTCTTGCCATATCTGCAATAGCATTAGCAATCAAGA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ACAATACTCGCAGACTTAGAAGATTTTTCAAGCCTAGCG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AAAAGTTAGTTGCTAAAGAAGTTGGTGCGGCTGTCGG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATGCTATCCTATTAATTGCCTTATCAAAATAGTAGTGATTG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AATGTAAAATAGACAACATGAATCCATCATTGTAG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATTATCTATCTAATTGATTATGTTGTATGTAACTA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TCAATCAAGTCCCAACATAAAGGCACTAGTTATCAAAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AATCCAATTAAGAACAGAAATAAATAACTCATCTT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC

>NC_019772|3|3|57672-61179|CRISPRCasFinder
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AATCAAATTCAGCTACGTACTTCGCGAAGCTTTCTAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TCTTATCGTCTTGTTCTGCGGTTAGACCGATGCT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GCTACAATCACACAGAAAAAATTTTTATTGACCTAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATTAGATCAGAATATTCATCTGTGGCAGATGAGCCAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GTTTCACCACTGCTACCAGACCAACTACCTTTTTTCTTG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AAGCGTAAATATTTCCCGTATGAATTGGGGTAGGGTTTC
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AAGACAATGCAGGAATTAAAAGGATACACACCAACA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GCTTTGTCTATAGTTTATAAGGGTTAGAGTGATCCAAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AATTCTTCTTGTTTCTGGATGTTATAGAATTTAGAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	CTCTTTTTATCAATCTTCCTCTGTAATCTTTTGAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GTTCTGGAGGAGGAGGATCAGGGGGTGATGCGAGT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TCAACGCATATGGCGCGCAAGGTACAAGTTTCTGGACGA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TTCAGTTGGAATACAACAATAGGCGAAGTCCAGCTTTA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TATCTTACTATAGATACGACTATAGATAGTGATATAGGGG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TCAATCAAGTACAATGGTGGCAATATCTCTTAAAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ACCCTCGCTGTCTGGCAATTCTACTAGATGAGCTAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TAGTCAGGTAGCTGCTGATTACCGTTTTGTGCGTA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATCCTACTAACCGATGGCGAAGATCTCAACATAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GTTAAATCTCTGATTCCAAGCTCTCTGTTATTCGCTGCTATA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TAATATCTGGGGGATTGAGTGCGATCGCCAAATAGCAG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AGGAATTTAACTCATTTTGTAGGTTAGTTTCTTCA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TCTTCCAAAAATCAAAAGATATTCTTGCTGACAAGCAATCAAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TACACTAAAAAAATAATCCCCCAAACCGTCGTAACCGG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GAGAAAATGACAGAAGAACAAGCAAAAGAACTTTTAAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TTGGCGTAAATGTAGCCTATTAAATCCCCCTCAAGC
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AACAATGGTTCGGGTTTCTCTATGTCTTGACCCTTGCC
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATATCGTTATATAGTAATACGCGAGGATAGCGATATA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GCCAATTTCAGAAAGATTGCCAACAAATGATTTAAGAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TTAAAATCAGCCATGATCTTTAATAATTAAATTTA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATTTCTTCCAGGGTTGGTTTATGGTGGAAAACCCTG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	CAGAGAATCCAAACATCTTTAGAATCACCGCCAACC
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AAAAGCTTGTTGTTTGTCAAGATGAATGTCGCAGAAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TAAATGTACTATGCTGCTCTGGCATTTAAAATA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TTAAGAATATGACTAATTATTGCAATACAGGTGA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	CAACTATCGAAGCGGTTTCTTTCTGCTAAGTCCAATG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	CAAACAGCCATAGACAACACTATTGCCACCGTTGGCG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GAGATACAAAGCAATCTGAGAAGTCTTTGCCACCTATA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TAATAAGCTTCCTTTATCGATCTAAAAGCTTCAGTA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TAACATAAACCCATAACCCTTGTCAAGCATGACTT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TTCTTGCCATATCTGCAATAGCATTAGCAATCAAGA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ACAATACTCGCAGACTTAGAAGATTTTTCAAGCCTAGCG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AAAAGTTAGTTGCTAAAGAAGTTGGTGCGGCTGTCGG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATGCTATCCTATTAATTGCCTTATCAAAATAGTAGTGATTG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AATGTAAAATAGACAACATGAATCCATCATTGTAG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATTATCTATCTAATTGATTATGTTGTATGTAACTA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TCAATCAAGTCCCAACATAAAGGCACTAGTTATCAAAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AATCCAATTAAGAACAGAAATAAATAACTCATCTT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC

>NC_019772|3|2|57672-61179|CRT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AATCAAATTCAGCTACGTACTTCGCGAAGCTTTCTAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TCTTATCGTCTTGTTCTGCGGTTAGACCGATGCT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GCTACAATCACACAGAAAAAATTTTTATTGACCTAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATTAGATCAGAATATTCATCTGTGGCAGATGAGCCAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GTTTCACCACTGCTACCAGACCAACTACCTTTTTTCTTG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AAGCGTAAATATTTCCCGTATGAATTGGGGTAGGGTTTC
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AAGACAATGCAGGAATTAAAAGGATACACACCAACA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GCTTTGTCTATAGTTTATAAGGGTTAGAGTGATCCAAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AATTCTTCTTGTTTCTGGATGTTATAGAATTTAGAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	CTCTTTTTATCAATCTTCCTCTGTAATCTTTTGAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GTTCTGGAGGAGGAGGATCAGGGGGTGATGCGAGT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TCAACGCATATGGCGCGCAAGGTACAAGTTTCTGGACGA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TTCAGTTGGAATACAACAATAGGCGAAGTCCAGCTTTA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TATCTTACTATAGATACGACTATAGATAGTGATATAGGGG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TCAATCAAGTACAATGGTGGCAATATCTCTTAAAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ACCCTCGCTGTCTGGCAATTCTACTAGATGAGCTAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TAGTCAGGTAGCTGCTGATTACCGTTTTGTGCGTA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATCCTACTAACCGATGGCGAAGATCTCAACATAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GTTAAATCTCTGATTCCAAGCTCTCTGTTATTCGCTGCTATA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TAATATCTGGGGGATTGAGTGCGATCGCCAAATAGCAG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AGGAATTTAACTCATTTTGTAGGTTAGTTTCTTCA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TCTTCCAAAAATCAAAAGATATTCTTGCTGACAAGCAATCAAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TACACTAAAAAAATAATCCCCCAAACCGTCGTAACCGG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GAGAAAATGACAGAAGAACAAGCAAAAGAACTTTTAAT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TTGGCGTAAATGTAGCCTATTAAATCCCCCTCAAGC
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AACAATGGTTCGGGTTTCTCTATGTCTTGACCCTTGCC
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATATCGTTATATAGTAATACGCGAGGATAGCGATATA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GCCAATTTCAGAAAGATTGCCAACAAATGATTTAAGAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TTAAAATCAGCCATGATCTTTAATAATTAAATTTA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATTTCTTCCAGGGTTGGTTTATGGTGGAAAACCCTG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	CAGAGAATCCAAACATCTTTAGAATCACCGCCAACC
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AAAAGCTTGTTGTTTGTCAAGATGAATGTCGCAGAAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TAAATGTACTATGCTGCTCTGGCATTTAAAATA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TTAAGAATATGACTAATTATTGCAATACAGGTGA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	CAACTATCGAAGCGGTTTCTTTCTGCTAAGTCCAATG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	CAAACAGCCATAGACAACACTATTGCCACCGTTGGCG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	GAGATACAAAGCAATCTGAGAAGTCTTTGCCACCTATA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TAATAAGCTTCCTTTATCGATCTAAAAGCTTCAGTA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TAACATAAACCCATAACCCTTGTCAAGCATGACTT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TTCTTGCCATATCTGCAATAGCATTAGCAATCAAGA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ACAATACTCGCAGACTTAGAAGATTTTTCAAGCCTAGCG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AAAAGTTAGTTGCTAAAGAAGTTGGTGCGGCTGTCGG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATGCTATCCTATTAATTGCCTTATCAAAATAGTAGTGATTG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AATGTAAAATAGACAACATGAATCCATCATTGTAG
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	ATTATCTATCTAATTGATTATGTTGTATGTAACTA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	TCAATCAAGTCCCAACATAAAGGCACTAGTTATCAAAA
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC	AATCCAATTAAGAACAGAAATAAATAACTCATCTT
GTTTCGATATAACTAATCCCCGCAAGGGGACTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019772.1\|WP_015217582.1\|50024_50972_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_081593763.1\|47320_47944_+\|DEAD/DEAH-box-helicase	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_019772.1\|WP_015217580.1\|44108_44714_+\|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	gnl\|CDD\|274900
NC_019772.1\|WP_081593764.1\|47924_49964_+\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_019772.1\|WP_015217590.1\|61510_61882_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_042466322.1\|64883_66323_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
NC_019772.1\|WP_150111132.1\|54614_55601_+\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl\|CDD\|337605
NC_019772.1\|WP_081593666.1\|67281_68262_+\|transposase	unknown	unknown	gnl\|CDD\|376573
NC_019772.1\|WP_015217584.1\|52902_53865_+\|DevR-family-CRISPR-associated-autoregulator	cas7	pfam01905_cas7_CAS-I	gnl\|CDD\|376656
NC_019772.1\|WP_015217588.1\|56195_57173_+\|type-I-D-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|274976
NC_019772.1\|WP_042466315.1\|63904_64183_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015213505.1\|62262_62985_-\|IS1-family-transposase	unknown	unknown	gnl\|CDD\|281403
NC_019772.1\|WP_015217587.1\|55607_56192_+\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
NC_019772.1\|WP_150111133.1\|64420_64651_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|226181
NC_019772.1\|WP_015217598.1\|68301_69924_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223021
NC_019772.1\|WP_015217592.1\|63218_63557_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217589.1\|57169_57463_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_019772.1\|WP_150111131.1\|53965_54598_+\|hypothetical-protein	cas5	cls000048_cas5_CAS-I-A	unknown
NC_019772.1\|WP_015217593.1\|63560_63908_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217597.1\|66359_67076_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_019772.1\|WP_081593763.1\|47320_47944_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.17934e-23
NC_019772.1\|WP_015217580.1\|44108_44714_+\|TIGR03984-family-CRISPR-associated-protein	gnl\|CDD\|274900	TIGR03984, hypothetical_protein_FrEUN1fDRAFT_5778, CRISPR-associated protein, TIGR03984 family. Members of this protein family are found exclusively in CRISPR-containing organisms, in operon contexts with RAMP (repeat-associated mystery protein) proteins also linked to CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats).	1.62986e-32
NC_019772.1\|WP_081593764.1\|47924_49964_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	8.83549e-28
NC_019772.1\|WP_150111132.1\|54614_55601_+\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl\|CDD\|337605	pfam10040, CRISPR_Cas6, CRISPR-associated endoribonuclease Cas6. Cas6 is a member of the RAMP (repeat-associated mysterious protein) superfamily. It is among the most widely distributed Cas proteins and is found in both bacteria and archaea. Cas6 functions in the generation of CRISPR-derived guide RNAs for invader defense in prokaryotes.	7.4209e-14
NC_019772.1\|WP_081593666.1\|67281_68262_+\|transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	3.66313e-08
NC_019772.1\|WP_015217584.1\|52902_53865_+\|DevR-family-CRISPR-associated-autoregulator	gnl\|CDD\|376656	pfam01905, DevR, CRISPR-associated negative auto-regulator DevR/Csa2. This group of families is one of several protein families that are always found associated with prokaryotic CRISPRs, themselves a family of clustered regularly interspaced short palindromic repeats, DNA repeats found in nearly half of all bacterial and archaeal genomes. These DNA repeat regions have a remarkably regular structure: unique sequences of constant size, called spacers, sit between each pair of repeats. It has been shown that the CRISPRs are virus-derived sequences acquired by the host to enable them to resist viral infection. The Cas proteins from the host use the CRISPRs to mediate an antiviral response. After transcription of the CRISPR, a complex of Cas proteins termed Cascade cleaves a CRISPR RNA precursor in each repeat and retains the cleavage products containing the virus-derived sequence. Assisted by the helicase Cas3, these mature CRISPR RNAs then serve as small guide RNAs that enable Cascade to interfere with virus proliferation. Cas5 contains an endonuclease motif, whose inactivation leads to loss of resistance, even in the presence of phage-derived spacers. This family used to be known as DUF73. DevR appears to be negative auto-regulator within the system.	2.82867e-60
NC_019772.1\|WP_015217588.1\|56195_57173_+\|type-I-D-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274976	TIGR04093, hypothetical_protein_L8106_25395, CRISPR-associated endonuclease Cas1, subtype CYANO. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes a clade of Cas1 limited to the CYANO subtype of CRISPR/Cas system and most often the type found there.	3.8696e-148
NC_019772.1\|WP_015213505.1\|62262_62985_-\|IS1-family-transposase	gnl\|CDD\|281403	pfam03400, DDE_Tnp_IS1, IS1 transposase. Transposase proteins are necessary for efficient DNA transposition. This family represents bacterial IS1 transposases.	7.37922e-23
NC_019772.1\|WP_015217587.1\|55607_56192_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	3.97776e-35
NC_019772.1\|WP_150111133.1\|64420_64651_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|226181	COG3655, COG3655, Predicted transcriptional regulator [Transcription].	3.12787e-07
NC_019772.1\|WP_015217598.1\|68301_69924_-\|hypothetical-protein	gnl\|CDD\|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	0.000349272
NC_019772.1\|WP_015217589.1\|57169_57463_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.61136e-28
NC_019772.1\|WP_042466322.1\|64883_66323_+\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	2.37378e-05

>NC_019772.1|WP_015217589.1|57169_57463_+|CRISPR-associated-endonuclease-Cas2
MTTLFYLIIYDLPDNKAANKRRTRLHKMLSGYGKWTQYSVFECFLSAVQFATLQTKIEKLIKPDEDSIRMYVLDAGSVKRTITYGSEVPRQEQAIII
>NC_019772.1|WP_015217588.1|56195_57173_+|type-I-D-CRISPR-associated-endonuclease-Cas1
MTTLYVIQPDAVLSKDYEAFQVALRQEDGSWKKRKVAAQTVNEVILMGNPQVTGDAFVYALELGMPVHYLSSFGKYLGSALPKSSRNGQLRLAQYAVYHDSVRRLELVKAIVSAKIHNQYNVLYRHNEKDNPLKERKNLVKTQQTLDQVRGVEGLAAREYFACWQRMVGKQWTFNGRNRRPSTDPVNSLLSFAYALLQGQVMAGVHIAGLDPYIGYLHEVHHGQPAMVLDLMEEFRALIADNLVLSLLHKHEIKPEDFHESLGAYRLKDNARKTFLQAFDKKMNDEFKHPVFDYRCTYRRAIELQARLLSRHLQEGIPYKPLSLR
>NC_019772.1|WP_015217587.1|55607_56192_+|CRISPR-associated-protein-Cas4
MNEDYLPLAYLNAWEYCPRRFYLEYVLGEMEDNEHIILGRHVHRNINEEGTFQDGETLIHQQQWVWSDRLHVSGIIDAVEEYDSQLVPVEYKKGKMAQHLNDHFQLCAAALCLEERTGRTITYGDIFYHANRRRQTVAFTPQLRQMTEQAIALAHVASQNKMPRPIDHTKKCESCSLQGICLPFEVKQLQSQDY
>NC_019772.1|WP_150111132.1|54614_55601_+|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MTLILRQDAKLINSVTLESWLSDTQLVPIWIPLQIDNGITKIMPVLPDSKLYPQLMESICQHICRGRVSPSLEWQNKPYQPTGVEVDSNALHIILVSISANAPLPATLGRAIHAQFFQWVAHADAALAEYLHQHNILPMTVAIQYSSRQRMQLRITLLKPELLAPLLWGLSSNLGGEITLAGVPCQLGKWINIIQSRSFEKLAEIPLQNTIELQFISPTSFKQNQNIQPFPLPELVFGNLLRRWNKFAPVELQFPQVEWQGLVSAFELKTHALKMEAGAEIGTKGWVKYRFSDPEQARIATILANFAVFSGVGRKTAMGMGQTALKNQ
>NC_019772.1|WP_150111131.1|53965_54598_+|hypothetical-protein
MAARSNLVPTPYAIKMALLKVLLESQGRHHQRDFDQWIKTEFTWIRDLTIYIWPPEKLVVNRNGYKLRYYDQTADKADKTRPTIPMQDGFVFREWVFLQGHLQICCSAGSHVSELEQLFAQINYFGKRSCFFQYLPDFKQETSEPLFQPNFATGFTIQLMDDLGEKTTFNRINPFSTDKAQLDKDRVIKSGFLPLKLVATSARYDIYQRY
>NC_019772.1|WP_015217584.1|52902_53865_+|DevR-family-CRISPR-associated-autoregulator
MTKAKFPVYSISISGLLSLQLHALNNEGNEGNQSLTRRYYIIQDGMDEPEYVNGISGDMFKHIQSEHLHRVALESELSLSEGGKQFNPDRIGYDLEKNLSVFTDKDTDLAAKTGKVLQLCTISDLEGFMVTVKGGQTLKRDSVIEFGAVVGLPNLVKTQSYFHAKYGVDNPTPYNVQVSSGLYATVLNIEAFRIGYNPHTFNYSIDVSERKKRLDALLKSVLYTYLQPNGAKRNTHLPHPDNFEGVITVSSRRCPAPMISSLEGSYKTQIDSLAATLNNINGADTIRCFKFENMAEFADQIEILIAQTLPWDSENAEAIS
>NC_019772.1|WP_015217582.1|50024_50972_-|hypothetical-protein
MSEVKADYDGAWKEGVEKYFEAFLTFFFPQIYSEIDWTRGYEFLDQELQQLMRESEVGKQFVDKLIKVWLNDGKETWLIIHLEIQSQVDTGFPKRMFSYHYRIFDRYGQEVVSLAILGDNQASWRPQEYSYERWGCRLSLQFPTVKLLDYQPRWSELEQSDNPFAVLVMAHLRTQATTKNLTGRLQWKLSLVKRMYELGYSREKILQLFDLIDRLMTLPPDLDLNFKTELKQFEDDKKMAYITSIERLGIAQTLQKSIVKIIKTRFQDAPSQLVEQINKIYDHERLNQLLEQAITIGSVPDFQELLTQENTGTDS
>NC_019772.1|WP_081593764.1|47924_49964_+|CRISPR-associated-helicase-Cas3'
MEIIQIEDTDLQAIEGKRRRIFQAKSHPLNALEIIADIHTNQRKRVIIICNTVSQAQGLYRDLRELNHDETLNLTLLHSRFLPEHRAQKETFLKETFAENWQDDGTCYVLISTQVIEAGINITCQVMHSQLCPMNSLLQRAGRCARFQDEQGQVLVYRTIEVNQAYSTLAEADLEPETESTDKKQSFLPYPRETCESTWQVLQTHTESNQVNENVGFRTEENWINQVHTTEDLLQQQRRQNNQMQFEQHFEAAFFRGDQSFASELIRSVDSRSLFVWEETGFIDFEEEPIDPRKLMAFSVPVSTLCKVWRDSKNLEFGTDWIFKRIEAPKDKAETYSQPVCTEIKSRDSLINSIKILVNPRFIYYDENIGLLIGINEFGNGFISPPKPQRTIASEYRYNMDTYIGHLGCMWTCWHKPFKTLRLKNGEAESTIYNSIRNELLPAGTKLIKNKIFPHIQESEAAALFEILVFFAIFTHDLGKLQIKWQQVMRGWQAIAHSSFHGQNPKQHLLAHTDYNPDDKDQKTALKDHEKKHKRPNHAVESAFLARDILKQSLVPVLRDYFEADNEQIQYICHTVIMAAGRHHSAWAGGWSIADITKIKTIELHPEAQRAIAQSWQSMTRFLSQILPLTPANLSKSIYPIKKEFDLNQLNTADEFEYFHLYLLVVRALRLCDQRSVQL
>NC_019772.1|WP_081593763.1|47320_47944_+|DEAD/DEAH-box-helicase
MIDAHFQTLTTFPPRNFQREAIAKLLHRQNILLRAPTGSGKTETAIAPFLFAKTLNLDFPNKLIYVVPLRTLANSLRQRTETLVQRWSQTQNIPCPVVTLQTGENPEDPRFEGDIVFCTIDQMLSSFLNIPYSVGRGSANVNSGAIFASYLVFDELHLLDPDRSFTTVLKVLQQVKGISPFLLMTATLTNELATQIQGLIDNGNNSN
>NC_019772.1|WP_015217580.1|44108_44714_+|TIGR03984-family-CRISPR-associated-protein
MNQDLCQELSTETIEKSLENWLKQQAITQDYQLCYVLAHAEDGVIWGNFEVESGILKTSNQAFPEYDFPALRLSTLQQCRIFGEAGEILLWNSNSTWRSRLILQSQVSELLKQEKIGLIPESQILWGTQGKENGNFTLLSDGSQGLKYAAPITGMTVSQDKQKQYRPLRLEVHHYFCYDQDGVARIFLSRLVSLKEKIYES
>NC_019772.1|WP_015217590.1|61510_61882_-|hypothetical-protein
MADLSGAWLGTYWQQGTPTRFEATFIQSGNTLAGNILDNSYLGEACLNGEVIGRRVQFTKQYLLHKQMPVNYQGTISGDDDFIQGIWDLGNFGSGNWEAHRSGENLNLELKNRLENRVPVSVK
>NC_019772.1|WP_015213505.1|62262_62985_-|IS1-family-transposase
MSISRPTCPNCGSQHIVKNGKIHNQKPKYQCQNCKRQFIENPTNKVISKDTIELIDRLLLEKIPLAGIARAARVSETWLQKYVNNKYAQIPTQVNVSAKPRGKLTIECDEAWSFVGHKGNKQWIWLALDKKTREIVGVYIGDRSEDGARGLWNSLPPVYRQCAVCYTDFWAAYAQVIPSKRHQAVGKESGKTNHIERFNNTMRQRISRLVRKTLSFSKKLDNHIGAIWYFIHHYNSCCSA
>NC_019772.1|WP_015217592.1|63218_63557_-|hypothetical-protein
MTQPSLPQPKLEPSGITSDQYFEFTPEKLEMSNGYLGYGGQDNLGFHLAVLTNMGLLTAIRNTNLSLWVEALDCVMREKLAKVDAEPEVAEAMLNRFNQAMLDLEAIIDYLE
>NC_019772.1|WP_015217593.1|63560_63908_-|hypothetical-protein
MTKFTTLQATFIKDDVSIRLNNLNNHLTQIQALSQDPANNETVKALIRETIYFIEWIAPDIEFDHAFELANLARFLTRWLFNVEAWNHTKTENQFTHELENWNNRILQISQLLGA
>NC_019772.1|WP_042466315.1|63904_64183_-|hypothetical-protein
MLQELKFYIKVAVDLERRVLAGGGEMHFYCEQALLEDGSLQQDIWAASFRPENKQIIYESMVNLRPRQNRSMEIQDAKIRKQVALIIMEFLG
>NC_019772.1|WP_150111133.1|64420_64651_-|helix-turn-helix-domain-containing-protein
MIRWKLNEIMARHRVKGKDLANYLGISANAVSALRKAEIVPEIGGSRWELICLGINELSKIDETISPLDLIEYVPD
>NC_019772.1|WP_042466322.1|64883_66323_+|hypothetical-protein
MTQNQVFRVALADIKANAQQKLEQYIDKQADTIAPFALNYSFDYNQFAETALQNKAKTTLANFIGFVRQTFDGLLASGKALQDLYYDCLAFCPNGKQVFHTWLESNDFGASRYIASSAMKIYTWFDQLPERIQRLVREKVQNWSVAALSQLTKVAHHLIKELVDSGKKTAAQVKATTEKTATSAKKTNSTIVATASNERIDAPELAPGMRIVVVVNGDWKGYKGIITAKWKANDNESWWVLLDHVVAQGSFTKTLFKPEQIQLEVLSNQSGSKTSPKETFTARQVEQKIAEALAEQEREQAEVELARFTEIRDAALQAAAVELKAAQEHAQKMAQDKEKLIEQLIEKDRQLVTVQNLSIKNQQLEQRVVQLEKALERAGQNSWQNTFSGQAATVVNSELEATIAPLMSEVERLNEVVLTREQEVAQLKAVNHKQQAELTNIVNLITNTNEMNSNQTEIVEQFVQLKTLLQEMKINEVIT
>NC_019772.1|WP_015217597.1|66359_67076_-|hypothetical-protein
MKPFFAYVIATNTLISGVTAPIVQAQTSAYRVLERDTAANTLIQVQVTPGRATPISFNQTDETISYILVADPSRLVYTTDTDLKTGQATTIFLRVIKPLKFPQATTTAITNLLVQTVDEEGQKRLYNFDIIPQRGKSGYVGIQIANAIPGQQKLLIDKNRQVTVDDIETGLKTAINRGYTHSNDPIVSKVQKFLVLLRTHKVTIPEVAKSVDVPLAVISELGKMAINQRYCQKLIPGC
>NC_019772.1|WP_081593666.1|67281_68262_+|transposase
MYTLFLLSEPKYGGCSRLAEILGDVSHDSVNRFLLRERYEPKDLFSIIEKIINLVGGILSVDDTVIEKIYSDPKNAELISYFWSGKAHKTIIGLNLITLYYSDINGNSVPINYRIYDKKEGKTKNDYFREMVSEIISWGVKPRMVTGDSWYSGVENLKFLKNQKLGFLFGIEKNRTVSNEPQKYCQVGILDIPEEGLRTHLKEFGFIKLFRKDFKKEDSRHYILYLPDEEKIKDITRSTFVTIHDTHWGIETFHRAIKQVCGICRFMVRDTCAIKTHIFCSLQAFVKLEFMRSENIISNWYEVQRNLFTSVVREHIFANLRKDAII
>NC_019772.1|WP_015217598.1|68301_69924_-|hypothetical-protein
MDNSHQNHEFDSYENSANYSLESHTNNGNHRSTQTAVDEENISPEEEQKLAGHNPTTNQLISQEYRLKQDQEAAVERPLAEKPGVRLVSVVTLVGIVIASGSTLWFGFLQPKPPAKQVAKTNDSSPSSEPVLDESAELKSRLAFQDQQQQINVKPVPTISPSPASPAKPQPSPQVRAVRQTVAPRTTAVRVAEPAPRVMRYSSPASVNSPVSHTVPRTIQQPVQQAENDVDPLQQWKQLASLGQSQISNSTLSTQEKPTASTASNQTLKTLKPTTPPPQETELRTVLVGSKSVDSQTELTPGMMGILNRTPVDLVNSNVGSNKDVALGTSVRGKVIMPMIWDEGGNNPNDRFAVELTESLKATDGTEALPAGTVVVAQTTAVGKRNNLVSASAIALVYPNSQGTVKQETIPANTLLIRGGNKRPLIAQKLNDVGSEIAQQDLLVGLLSSLGKVGSIVNQPRTQSSTVVANGTFNQSTVSSTADPQIWAAALEGFFSPVSERLSRRSDQAVQELLQRPQIQFLREGTEVSVVVNNFLKIEQ

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Crispr_ID: NC_019772_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019772_4

90830-90926

Orphan

A:N

Consensus_repeat	Method
AAAAATGTCCACAATTTGTGGAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019772_4

>merge|NC_019772|4|90830-90926|CRISPRCasFinder
AAAAATGTCCACAATTTGTGGACAAAAATCGAAGTTCTTAATCTTTCACAACCGGGTTAGGTGCTAGTTCCCGCAAAAATGTCCACAATTTGTGGAC

>NC_019772|4|4|90830-90926|CRISPRCasFinder
AAAAATGTCCACAATTTGTGGAC	AAAAATCGAAGTTCTTAATCTTTCACAACCGGGTTAGGTGCTAGTTCCCGC
AAAAATGTCCACAATTTGTGGAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019772.1\|WP_150111127.1\|99183_99636_-\|peptidoglycan-binding-protein	unknown	unknown	gnl\|CDD\|366659
NC_019772.1\|WP_015217606.1\|80260_80803_+\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217611.1\|86624_89909_+\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|223627
NC_019772.1\|WP_171815840.1\|93826_94645_+\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217608.1\|81346_81880_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217604.1\|77495_79634_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368388
NC_019772.1\|WP_015217603.1\|76677_77301_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237495
NC_019772.1\|WP_015217613.1\|92467_92890_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217617.1\|94740_95901_-\|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl\|CDD\|223715
NC_019772.1\|WP_015217620.1\|97739_97943_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217618.1\|96249_96975_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NC_019772.1\|WP_015217615.1\|93427_93646_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217621.1\|98475_99096_+\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217614.1\|92951_93332_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217609.1\|82138_85510_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217619.1\|97158_97737_-\|siphovirus-Gp157-family-protein	unknown	unknown	gnl\|CDD\|368503
NC_019772.1\|WP_015217610.1\|85807_86416_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371004
NC_019772.1\|WP_015217607.1\|80799_81183_+\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217602.1\|73181_76418_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274279
NC_019772.1\|WP_015217612.1\|89915_90755_+\|SWIM-zinc-finger-family-protein	unknown	unknown	gnl\|CDD\|226729

Protein	Function_ID	Function_description	E-value
NC_019772.1\|WP_150111127.1\|99183_99636_-\|peptidoglycan-binding-protein	gnl\|CDD\|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	5.67716e-12
NC_019772.1\|WP_015217618.1\|96249_96975_+\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.44999e-58
NC_019772.1\|WP_015217602.1\|73181_76418_-\|hypothetical-protein	gnl\|CDD\|274279	TIGR02746, hypothetical_protein, type-IV secretion system protein TraC. The protein family described here is common among the F, P and I-like type IV secretion systems. Gene symbols include TraC (F-type), TrbE/VirB4 (P-type) and TraU (I-type). The protein conyains the Walker A and B motifs and so is a putative nucleotide triphosphatase.	0.000144994
NC_019772.1\|WP_015217611.1\|86624_89909_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|223627	COG0553, HepA, Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair].	2.56897e-117
NC_019772.1\|WP_015217619.1\|97158_97737_-\|siphovirus-Gp157-family-protein	gnl\|CDD\|368503	pfam05565, Sipho_Gp157, Siphovirus Gp157. This family contains both viral and bacterial proteins which are related to the Gp157 protein of the Streptococcus thermophilus SFi bacteriophages. It is thought that bacteria possessing the gene coding for this protein have an increased resistance to the bacteriophage.	2.52667e-10
NC_019772.1\|WP_015217604.1\|77495_79634_-\|hypothetical-protein	gnl\|CDD\|368388	pfam05327, RRN3, RNA polymerase I specific transcription initiation factor RRN3. This family consists of several eukaryotic proteins which are homologous to the yeast RRN3 protein. RRN3 is one of the RRN genes specifically required for the transcription of rDNA by RNA polymerase I (Pol I) in Saccharomyces cerevisiae.	0.000100916
NC_019772.1\|WP_015217610.1\|85807_86416_+\|hypothetical-protein	gnl\|CDD\|371004	pfam10359, Fmp27_WPPW, RNA pol II promoter Fmp27 protein domain. Fmp27_WPPW is a conserved domain of a family of proteins involved in RNA polymerase II transcription initiation. It contains characteristic HQR and WPPW sequence motifs. and is towards the C-terminal in members which contain Fmp27_SW pfam10305.	0.00312893
NC_019772.1\|WP_015217603.1\|76677_77301_-\|hypothetical-protein	gnl\|CDD\|237495	PRK13765, PRK13765, ATP-dependent protease Lon; Provisional.	0.00671782
NC_019772.1\|WP_015217612.1\|89915_90755_+\|SWIM-zinc-finger-family-protein	gnl\|CDD\|226729	COG4279, COG4279, Uncharacterized conserved protein [Function unknown].	1.58562e-100
NC_019772.1\|WP_015217617.1\|94740_95901_-\|hybrid-sensor-histidine-kinase/response-regulator	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.89931e-51

>NC_019772.1|WP_015217612.1|89915_90755_+|SWIM-zinc-finger-family-protein
MVKFSRTWWGDRFIKALENFTDDGRLQRGRSYASSGKVLNFEIEQNHITARVKGSVNPYFGVYKEPTYNISIEIKSIPKSSWNEAIDKLSSKASIVSRLLLNEVPENIEDTFKQLGLNLLPHSSKDFQTKCSCPDYANPCKHIAGVYYLVASQLDNNPFLLFELRGLSKEELQTKLAKSNLGKALSQELNTQEVSLESSTSFYTKLEKQSVDEKPSVREFWLGKKRLPQTIEVPSSSGISAILVKKQGDFPAFWHKDNSFIETMEELYQRVKTKNQSLL
>NC_019772.1|WP_015217611.1|86624_89909_+|DEAD/DEAH-box-helicase
MKIVHGTWIPHTETDFIQSGSFYLWVETPVPKSSRNHKQQIHPGHLAKGELINFLVQELGIKEPAPQLSQRISAKYLALPTADNQPLPSPELIKYLEIEIPEEYTEFQYWQVDCYQTLTSVKNNTPAINIIRLLNDIHFLAINKGSDIQLGSDLLFWYHYTQSFKQIILKDQYIPTLKYRQLETPPPKGKSKKPIPPAFEIYAGWSIISEQYEANIQKYIEYMPLICVAGSNVENENIEFFDEKTLLRHFSESILNNIVAHTPSTAAFDKQITDSLVYYCFSQQHNPRTANITLEEYKQWQTWKSKITRSQSELPFHLCFQLNSPAAEQIDNWEMQFLVSSKQDPSLKLPLADYWPMSQKSKTGVQKEYGKDFETNLLLNLGYAARMYPQLWQGLETDTPVGMQLTLEEAFSFLQESAWVLEDAGFKVTVPAWYTPAGRRRAKLRLKASGKSRSATKGENKSYFGLNSLVQYEYELAIGEKAVTKQEWEQLINAKAPLVHFRGQWMELDRDKMQQLLEFWQSHGDEKPEMSVLEFLQRNAESGEDWDIEHDEILSDMMAKLQDKSSLEPISDQLNLQGNLREYQKRGVAWLEYLERLGLNGCLADDMGLGKSVQVIARLVQERELLASEEEIERGGDEGDGENKGNKGNKGEKRNRGDRQTKLSNVPPTLLIAPTSVVGNWQKEIAKFAPHLQSMIHHGSDRIQTAPEFKTACQQNDVVITSFTLARKDEKLLHSIKWQRIVLDEAQNIKNPKAAQTKAILKLSAKHRLALTGTPVENRLLDLWSIFNFLNPGYLGKEAQFRKSFEIPIQKDNDRIKSSTLKKLVEPLILRRVKTDKSIINDLPDKVEQKLYTNLTKEQASLYEVVVKDVEEKLQTVEGIQRKGLILSTLMKLKQICNHPAQFLQDNSEFSTERSHKLSRLVEMVDEAVSEGESLLIFSQFTEVCEQVEKYIKHNLRCNTYYLHGGTSRPRREKMITEFQEPDTEASVFILSLKAGGVGITLTKANHVFHFDRWWNPAVENQATDRAFRIGQQKNVFVHKFVAIGTLEEKIDQMIEDKKKLANAVVGNDESWLTELDNDAFKQLIALNKSAILE
>NC_019772.1|WP_015217610.1|85807_86416_+|hypothetical-protein
MTRKIERESINFKLPKPLVNALRAKARELETTATDLVIQGLDYVLNLTQEQTGERIENNLENRLHQLETELQKLTNNIEARTESSVEIKAGQDSKRLSNLEQNLETLARRLDILEQALLAGKYGGSQKPRRSSYPYQQQEVTIQPFPAQNLAQRLGLTASSLSAEREKLTTKEFISWTRNRDPRSIGWEYHPEDDLYHPLPQ
>NC_019772.1|WP_015217609.1|82138_85510_-|hypothetical-protein
MDLTTKVIEGSGLSIPIFDGSYNNGKGRYLSEPEIIKNSLLAQIFEPSELPSLLLVKIDSKNPDANHLRQRTFTDGIKRKLAFSSGDNYYFADDALRKKINRLFTTEPDTACRYGSLLVSNCYKGSETFTNLRVKIVDFTDPQYADDKTGDCHGKISPRLAKQLGGESNCPLQFRFAWMKCWAETDNSQTPKTSFLAKGTFLPDAKLTDAEGYDIIIDRSSIKGIKKSQLQDLIPCGEYQLPQAVIGNRGNAKATSYDNSWQFTIWYSEAAVQQDLSQATEAKAQELAKLQSNPLMLAKYIIQQYDKQQSQQEQTEETVNGIDDNTNNQVQESRWISLLRSDKYGQLIETPKFRKFATDYIANQWRDLAIKSGYSHNSGMAMPCDTLPRGTICVPHLPEGDVILTRYPIVNSDNIRLYSNVHDPELKKTRNVVWIHPKDAEEYHQADFDGDQLMVSPANKLPNIAKETLRAGEPGHFKPVKQRPKLAYTEITDEEGNLKYRDLSQIAAASSQNKVGLVATNIGRVQSSTPREGENTERFVRRQRKLLNRLFQALQVEVDSPKSAERLEDIKEIDGANLLADAKKWSESHPSYFFDFKKDDRLYRSFAMPADAPGAINVIAREVVNPLWEPTRIRSRDRHEFRYLFPKETLSVDALEWAEELKTRFQQSRDEIKERVGDDREAFNEELGKLYDSYRAEIDELFTTSEDRFEGAAALWHTQHTRPELDRHRKECLQLAAQMEITFSFEHNYEMPSAALPQDTYVLTVPFGKDAIKWKESLEDKGITFDATIHPQLPVIEFAFKDLSPKVAEKLAAKFGDNIYDSDELNIPKDLRIIAPVDHSWATSRQDAGVGALAYNLFTEEVCQQLQDFQFAEIKVLGIKYNDFADENFASQQWRKRSVTLEVGVFELPESHPDFYRYNGTPILQIDGQNLGTFAPDSPKLPVGTTFAATLKPEGSSIILKVNADSIELPEVTLVESEPKLNNAGELRAIHREFWRQEMFDNLVEAIGITYEQRQTNQSESKEIEQFKIGGQWTAYVQRSGDFIVRNENKRTICRGNIHTGEEIFPLSEAAASELEEMILERERLSANISFEKSLYSTQASLNHKQEISNNRNQSRSQNIELN
>NC_019772.1|WP_015217608.1|81346_81880_-|hypothetical-protein
MSQQESNYISFTSNQELATPMDLFLKEEWLRKSIQVEEEVSGNLGAGLDWGSSFDKLLLNSELFYRLKTLRISLNREVRLLLKDWNLGTATSTASATVREKLLKRFRLPPPNVKEHIQAVLQRDELFGEEFISNHQVLRELLGVMLTQEDWEMIASVAADVLKQQIINQVLIHKISA
>NC_019772.1|WP_015217607.1|80799_81183_+|hypothetical-protein
MSQIQELHQQAMDLAEMAQVAKLKNHSDLASQLSRQAFEKERLAAELIAGDLAAEPTRSILYRSAATLAIDCGEIHSAEHLIAIALSGNPPTEIAEELKDLFVQINIHKYFARRGLVFDEAKLQILS
>NC_019772.1|WP_015217606.1|80260_80803_+|hypothetical-protein
MNSNSKELVITKLKKGLPAITPAFGATLAEACAVCLNSQGYIQGIELTVKGEFTAVFQLYWQEVTDQMLRCWNDSEYTTEQAAYGIAFLIIQELTDYTVIERSRRGTGFDYWLGKKGDNNELPFQNAVRLEVSGIRKGDDSRIKARIKQKLEQVSPTDGTLPAYIVVVEFSNPLAFIVKK
>NC_019772.1|WP_015217604.1|77495_79634_-|hypothetical-protein
MATKTLTKPKRQQSSQNRTWENLTDRRKLRHIENTLDKAIASSIQNDSIQSHEDFKECVENYSQESGKAPITVELCVGGDDDDEIRGYRFYLTSDPGHRTSGKYLIKNLEGITNKDENYFTPSNIAEICGFAETELDDLDDELKDDLLDLDEENEEIDDIEDELDDLLNDDFNNELDDPDDLDEEDELPQGRVSVASTKPQAKTVTKPQSKSQPKTPTKTQDKIPTNKTATKKSKSQEPLDEASRLSATAATNGREVNGVNLGGLAGQLATLGIAVGQGVLEQLAAEADEKRLERILKQLQKQNDRVDNLTSRLQEIKPDLYEFQDSINSPNSSNFQISPNSRTSLNSQISSNSRTSLNSPNSQVVSEASTADNPVAVAAMKIGSKVDKLSSQLDPNNQSPPFELDQDASITEQLQQIEDYLQIISKRLDRLEKVVSRLEKQISAQQNSSVIASETTEETIQSNSTNQPENDVLGHLTKRQAQQQQIACANALVEFADVASELFDETPENITISSNKTLKVKQQGKQTEQTGISADVAIALQNTQGETLFAGTCTQGQWAIAQDNLTADEKIGICKLPQSKEEYALKATTQALIQKFQAQLPHKFNGDDKPIFTWAEKGKAKYDFEVVQLPNEKQTQLLQGFNPNRHNELVLDAVLVPGEPPEIRQCSIPLREMEALLDNQQSTRSQQADQDTAKQQKNKSKTKANKSEMQI
>NC_019772.1|WP_015217603.1|76677_77301_-|hypothetical-protein
MNHPKSPNSQFKLLPSAKVATNWKNQKINRTDLIFIVIALAMGIYLLATKPIFMTILGCASIIFLSMEYVIRTVPILEHYLGRKIRFWHLVTAIIAVTAVLDTFATPAHAIFLSGLEQFFVTLAQQSSQAGGGTNTLDANVVGLTFNLIRGAFLLLVAAASLFAYNQAQQGNDWRPIVTQVGLAFAIVIAIDVITFIFIGNGTGGGV
>NC_019772.1|WP_015217602.1|73181_76418_-|hypothetical-protein
MENNPRNEFIKVNQILGKQASIGPIPAEQLVPWIAIIIVAYIITNGLLSLGMGWFFATSFWLIVSWWILTGNQPHQFLDRWRKPPGNEWYNCNNIYISPLPENRPPWVRRRYSDSQINIRNKPLIVPNQYGGKSRFMPFQNEVNICCIAEIKKDDRQVAALLLEQGQSQYQLVFGFQIAGLHNILHESEVSEFAHAIEEGMKDLPIGERITFCTGCYSDDTQRQTQLNVLANDCHLKPISVLIRNEQLRVEELKNAGTRQQWQQIAFCTWTSDQQGSSQQKDFVGAVIEKCRNFGSWVVESITGNKRIYQETFFKKLLLQGFQQGFIQWEVLLNTKICLEVTPCSAGDLWQWLWNRFNEGAAPAIPQVITLEETATGLQLTETVTTDKHICTLLIEGTQGRSASPEHRSDHDRVYLTGKGKVCGVMTMTDPPLGWTNTQEQLKWVWKILSSSYVHDTEAWVEISRGNDFLIQDNLARQAKQSKVARTVAITKGQGRDIGAEIKQEESFEAQRRLYEGTKALHCAPVFLVYRHSAEELTHACNLLANSFETAKVLRERNIAWEIWLQTLPITCKRLLHDGNLSERRLTLDTQTIAGLMPLTIPKDIDQQGVEFLTSRGGKPIYVDLFHQQIGRALITGTSGSGKSVLGWRFAQEALVNNIPVVGMDISAGGNSTFKTAIELLGEQGAYYDISSGSSNLLEPPDLRRFDKSERERRMESWKDFIRKALVAISMGKVENPHLAQRVDAMLVKALDVFLKDADMIARYNRAFEMGWLSAEWQEIPTLPDFMKFCTRERLNLRSFEEIDRQALNQIQNQVSALLASRLGKAIARPSTFSPEPAIKFFALSGLTNEQDAYLMAINAHTACIRNALSHPKSLFIGDELSVLLRKDGFAQVIGETCATGRKEGIAVLLLSQDPDTICECSTGAQIMQNMTYRITGRITSTGVTSFQRYLGYPAHIISQNATEAFLPRISDLYSCWLVETGGRFWRSRFYPGEMMLASVANNQNEREARTRVMAQYPNTPKSRLLGLRAFANAYISALKENKGFQHIGQDVSTVQPNQFHSQSNSDEQAENRPLIAS
>NC_019772.1|WP_015217613.1|92467_92890_-|hypothetical-protein
MTEVNNDTTGSITITVQPQDNGQYICQMSSSLDDTRQNWQCYGQTKEHAIAIALEQLADEYRRIAEERQNINWETVERSDSGEPIAKHYHVILHYERIAEEESKFEAMHNTIMGNTVVENAKITVIAIDPNIPIDPLTRS
>NC_019772.1|WP_015217614.1|92951_93332_-|hypothetical-protein
MKLSDLSPETLEKIKLVRWDRIIEKHEGPEDWSSVLQYEEPEFMEIDGYPVLLPVDKSHHPNISIIRSIWAEDKKSLTLFLSDTTYEDDPFFSGFMTVCDRLKNENFFLAILYHEWFVIERTEIFD
>NC_019772.1|WP_015217615.1|93427_93646_-|hypothetical-protein
MARPGGNPDFGTKYRFDYGRDEPLSEQVKVLMHPQMKQHLKNLADLEKCTVPDLIREAIEQYLVAKQTTKVS
>NC_019772.1|WP_171815840.1|93826_94645_+|hypothetical-protein
MAVDAKNGDTTIAIFATEELTEEEERDRFRLERQVERAFSAAGKALRQLRDRKLYRSTHKTFEEYCKDRFSYNRSRSYQLIDAADVVDNLEECPQIVDILPTAEGQVRPLTKLEAEEQVSCWQEAVAAVGGKVPSGRIVKSIVDKLREKTNLPNPYYLGQVCQILPKDIPELKGKNGCWGIITHVGSYSCRITTWNGEYLVKIENLKSLDYDETECKYMQHLCQRLVRLHQVGNLDDAVGWLLTGLGKRYQPFLTPLQEKFLTIAEEEFGLI
>NC_019772.1|WP_015217617.1|94740_95901_-|hybrid-sensor-histidine-kinase/response-regulator
MTPFSWNSNSTESILLVDDSTKNVCLLKSTLKQEGYRVTVTDRDSEALIKIVESPPDLVLLDTFSPSIDGYEITRQIKQNSHLPFIPVLLVTNCDESSFIQGLQAGADDFLIKPVEQNELLARVRSLLRLKHSINQRDQIARQRCEDFMIKLTHDLRTPLTSAIQLLQMIQKGNFGYNFSEIRKHLQLLTESNQTLLSMVENMLEVYQYETGCKDLEFFLVDLWELAQKVVRELKPLAVVKNLALNAKLNNTQPSAVKVRGDRIELYRLLTNLIGNAIRFTDAGSVEIRLSSTVQGVKIEVEDTGIGISRSEKSFLFERFRQGKHQRRGSGLGLYLSCQIVEAHQGNISVSSTVGKGSIFTVYLPKSHQSYQIRLNEHSLDLEQGL
>NC_019772.1|WP_015217618.1|96249_96975_+|response-regulator-transcription-factor
MANIRAVIIEDHHLTRVGIRSCLNEQKNIQVVGDTETAAAGLELLQNTKPDIAIVDIDLPDIDGIALVQRFRQSMPPETAAQTKIIMLTSFAHEKMVLAAFASGADSYCVKTIKFELLLEALYMTYEGYSWIDPAIARIVLKHTRQLAAAVTAAKSNAAQTVTISAIDPEQASILEANPLTERETEVLELIVQGFTNQEIANKLYISMGSVKVYVRGILNKLSANHRTQAAVIALRAGLLD
>NC_019772.1|WP_015217619.1|97158_97737_-|siphovirus-Gp157-family-protein
MVLSLAQQSLAGLSQTAAHLWEQLTNCQTSEEEAAIITAIWETQEVQSEAVDIQAELALQLDAEIAAIKQRLEHLKAVHQSALLRLERWRQKLDETILEHNATGIIPEQIVGNLLRITIKENPPSCDVLVEAEKLPLKYRREKTVYSADKKAIIAAWKKGIPVDGTYVERKRRVVYALTATAIQDFKDSLLP
>NC_019772.1|WP_015217620.1|97739_97943_-|hypothetical-protein
MQQLIVIVTESVTTLKPKLTAVIDQNNQVTQKVISDLCLDANLDSGTIAILNQIEAEHNYYQTCGRW
>NC_019772.1|WP_015217621.1|98475_99096_+|hypothetical-protein
MSSAYYPIILYPPLARWLRNGNSEQKHIKASFQGCVALPDDKSIAKQGVSEKQFFQHLLAAFPGNLICQAVEFEIPGYPLRYSADFIFYHHSSGLALDIEIDEPYAGNTGKPHHCIDVDDDKIRNRFFLEHNWGVVRFAEIQVVRHPWNCCKVIAQTIAKLTGDNSVFMLLQRLADVPLQKCWTRREARLMAKNNYRQSYLLKKAF
>NC_019772.1|WP_150111127.1|99183_99636_-|peptidoglycan-binding-protein
MFSKKPDGYFDRETEKAVKRFQNIYGLKNDGIVGAATWSVLLGMRQKIDQSFPQLIYLLSPQSWFLWNQFLMISCILLGIYYSPLPGSEPTFSKALATAYGLTCIVPFLLDCLPLKQSKQPIFPVLQYAPYVLTGIFWKPILNFVGTLFN

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Crispr_ID: NC_019772_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019772_5

151821-154033

TypeIII

A:N

Consensus_repeat	Method
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	PILER-CR
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CRISPRCasFinder
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CRT

30 spacers

cas1,cas2,cas10,cmr3gr5,cmr4gr7

The CRISPR arrays of NC_019772_5

>merge|NC_019772|5|151821-154033|PILER-CR,CRISPRCasFinder,CRT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACGAGGAAACAGCATGAATAAAATGGGTGCTGAAACTCTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACGTTTTCTGTTTTGAATCTAAAAAAGAAATGATTTTCTCTCTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACTACATCAATGTAACTGTTCCATTGTTGTTAGTTGTACTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACTGTCTTTTCCATTCAAGATAACCCAAAATAGAAAGCGCTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACTTATCTCAATTTCTCTTGGTACCAATACTGCATCATTACTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACCTCAAATAAAACAACTTCCATCGGCTTTTTGTAGTCTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACTTGGTTGGAAACCTGAATGCGATACTGAGTTCCATGTTCTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACCTTGCGAATTTTTGAGCCTTTGTAAGGCTGAAGCTATTTCTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACCGGCGAGAGCCGCATGGGTGGCAACTCCGACTAATCTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACAAGCTTCTTCAACCATGCAGTTACAGTGTTGACACTTCTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACTTTTTTTCTAACTGTGTAAATTTCCACAACTTGACTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACTTTCAGACTGAGACTGAGCCAAAACTGGACTTGAAAAACTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACAATTCCACTATCGCAAAAGTTGGAGCAGGACTATCAGTTCTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACTGTTCGTACACCAACTAAACGCGTCATGGAGCCAAGCAACTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACCGTGACCTGTTGCCAGGAATATTAATGAAACAGCTAAACACTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACCTCTTTCCAGAACTCTTTTATCCTTCTCAGTGGGATTCTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACGAAAAAACAAGCGTAACATCGCCTGAACTATAAAAACTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACAGGAGGGTACCCTTGCTCTTTCAAGATTTTTTCATCAAACTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACCCTCACGTGGGCTGTATCAACCCAAATACCAGTTGTAAACTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACTTGCCGCCTTGGGAGGTGGAGTTTCCTCCGTTTCCACCACTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACTCGGTGGCGTTATTCTATTCAGTTTCTAAATCATTTTGCAACTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACTTTTCGTGCAGAATCAGCGAGATCTTTTGAGGCAGAACTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACATCTGATTTCCGGTTGTTATGCCTAACATAACAACTACTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACTCAAGGCAATTGCACTCATTGCCGTAGTCGACCACCAATACCTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACAGCAGATACAAACAAAGATATCAATATATAAGCTATACTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACCCTCTAAGTTGGACTGAAATTTTAGCTCTCTAAAACTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACCTCAAGACACATATTCTTTGCTTTTAGTAAAACATTCTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACATTGTCGATTGTTCCTTGGTCGCCCTTGGCAACCAACTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACTTTTAATAGAATACGAAACTCTAATTATAACAAATATCACAATCTTTTAACTTCTTAGAAAGTTGAACTAATGGAAACAACAAAATGTTGAAAGTGTTGCTTTGTAATTGAAATCTTTTAACTTCTTAGAAAGTTGAACTATTAGAAGT

>NC_019772|5|4|151821-153962|PILER-CR
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	GAGGAAACAGCATGAATAAAATGGGTGCTGAAACT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	GTTTTCTGTTTTGAATCTAAAAAAGAAATGATTTTCTCT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TACATCAATGTAACTGTTCCATTGTTGTTAGTTGTA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TGTCTTTTCCATTCAAGATAACCCAAAATAGAAAGCG
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTATCTCAATTTCTCTTGGTACCAATACTGCATCATTA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CTCAAATAAAACAACTTCCATCGGCTTTTTGTAGT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTGGTTGGAAACCTGAATGCGATACTGAGTTCCATGTT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CTTGCGAATTTTTGAGCCTTTGTAAGGCTGAAGCTATTT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CGGCGAGAGCCGCATGGGTGGCAACTCCGACTAAT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	AAGCTTCTTCAACCATGCAGTTACAGTGTTGACACTT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTTTTTTCTAACTGTGTAAATTTCCACAACTTGA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTTCAGACTGAGACTGAGCCAAAACTGGACTTGAAAAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	AATTCCACTATCGCAAAAGTTGGAGCAGGACTATCAGTT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TGTTCGTACACCAACTAAACGCGTCATGGAGCCAAGCAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CGTGACCTGTTGCCAGGAATATTAATGAAACAGCTAAACA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CTCTTTCCAGAACTCTTTTATCCTTCTCAGTGGGATT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	GAAAAAACAAGCGTAACATCGCCTGAACTATAAAAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	AGGAGGGTACCCTTGCTCTTTCAAGATTTTTTCATCAAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CCTCACGTGGGCTGTATCAACCCAAATACCAGTTGTAAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTGCCGCCTTGGGAGGTGGAGTTTCCTCCGTTTCCACCA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TCGGTGGCGTTATTCTATTCAGTTTCTAAATCATTTTGCAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTTTCGTGCAGAATCAGCGAGATCTTTTGAGGCAGAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	ATCTGATTTCCGGTTGTTATGCCTAACATAACAACTA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TCAAGGCAATTGCACTCATTGCCGTAGTCGACCACCAATAC
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	AGCAGATACAAACAAAGATATCAATATATAAGCTATA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CCTCTAAGTTGGACTGAAATTTTAGCTCTCTAAAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CTCAAGACACATATTCTTTGCTTTTAGTAAAACATT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	ATTGTCGATTGTTCCTTGGTCGCCCTTGGCAACCAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTTTAATAGAATACGAAACTCTAATTATAACAAATATCACAAT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC

>NC_019772|5|5|151821-154033|CRISPRCasFinder
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	GAGGAAACAGCATGAATAAAATGGGTGCTGAAACT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	GTTTTCTGTTTTGAATCTAAAAAAGAAATGATTTTCTCT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TACATCAATGTAACTGTTCCATTGTTGTTAGTTGTA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TGTCTTTTCCATTCAAGATAACCCAAAATAGAAAGCG
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTATCTCAATTTCTCTTGGTACCAATACTGCATCATTA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CTCAAATAAAACAACTTCCATCGGCTTTTTGTAGT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTGGTTGGAAACCTGAATGCGATACTGAGTTCCATGTT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CTTGCGAATTTTTGAGCCTTTGTAAGGCTGAAGCTATTT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CGGCGAGAGCCGCATGGGTGGCAACTCCGACTAAT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	AAGCTTCTTCAACCATGCAGTTACAGTGTTGACACTT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTTTTTTCTAACTGTGTAAATTTCCACAACTTGA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTTCAGACTGAGACTGAGCCAAAACTGGACTTGAAAAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	AATTCCACTATCGCAAAAGTTGGAGCAGGACTATCAGTT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TGTTCGTACACCAACTAAACGCGTCATGGAGCCAAGCAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CGTGACCTGTTGCCAGGAATATTAATGAAACAGCTAAACA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CTCTTTCCAGAACTCTTTTATCCTTCTCAGTGGGATT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	GAAAAAACAAGCGTAACATCGCCTGAACTATAAAAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	AGGAGGGTACCCTTGCTCTTTCAAGATTTTTTCATCAAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CCTCACGTGGGCTGTATCAACCCAAATACCAGTTGTAAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTGCCGCCTTGGGAGGTGGAGTTTCCTCCGTTTCCACCA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TCGGTGGCGTTATTCTATTCAGTTTCTAAATCATTTTGCAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTTTCGTGCAGAATCAGCGAGATCTTTTGAGGCAGAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	ATCTGATTTCCGGTTGTTATGCCTAACATAACAACTA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TCAAGGCAATTGCACTCATTGCCGTAGTCGACCACCAATAC
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	AGCAGATACAAACAAAGATATCAATATATAAGCTATA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CCTCTAAGTTGGACTGAAATTTTAGCTCTCTAAAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CTCAAGACACATATTCTTTGCTTTTAGTAAAACATT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	ATTGTCGATTGTTCCTTGGTCGCCCTTGGCAACCAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTTTAATAGAATACGAAACTCTAATTATAACAAATATCACAAT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	AACAAAATGTTGAAAGTGTTGCTTTGTAATTGAAAT
CTTTTAACTTCTTAGAAAGTTGAACTATTAGAAGT

>NC_019772|5|3|151821-154033|CRT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	GAGGAAACAGCATGAATAAAATGGGTGCTGAAACT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	GTTTTCTGTTTTGAATCTAAAAAAGAAATGATTTTCTCT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TACATCAATGTAACTGTTCCATTGTTGTTAGTTGTA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TGTCTTTTCCATTCAAGATAACCCAAAATAGAAAGCG
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTATCTCAATTTCTCTTGGTACCAATACTGCATCATTA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CTCAAATAAAACAACTTCCATCGGCTTTTTGTAGT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTGGTTGGAAACCTGAATGCGATACTGAGTTCCATGTT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CTTGCGAATTTTTGAGCCTTTGTAAGGCTGAAGCTATTT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CGGCGAGAGCCGCATGGGTGGCAACTCCGACTAAT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	AAGCTTCTTCAACCATGCAGTTACAGTGTTGACACTT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTTTTTTCTAACTGTGTAAATTTCCACAACTTGA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTTCAGACTGAGACTGAGCCAAAACTGGACTTGAAAAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	AATTCCACTATCGCAAAAGTTGGAGCAGGACTATCAGTT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TGTTCGTACACCAACTAAACGCGTCATGGAGCCAAGCAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CGTGACCTGTTGCCAGGAATATTAATGAAACAGCTAAACA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CTCTTTCCAGAACTCTTTTATCCTTCTCAGTGGGATT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	GAAAAAACAAGCGTAACATCGCCTGAACTATAAAAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	AGGAGGGTACCCTTGCTCTTTCAAGATTTTTTCATCAAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CCTCACGTGGGCTGTATCAACCCAAATACCAGTTGTAAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTGCCGCCTTGGGAGGTGGAGTTTCCTCCGTTTCCACCA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TCGGTGGCGTTATTCTATTCAGTTTCTAAATCATTTTGCAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTTTCGTGCAGAATCAGCGAGATCTTTTGAGGCAGAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	ATCTGATTTCCGGTTGTTATGCCTAACATAACAACTA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TCAAGGCAATTGCACTCATTGCCGTAGTCGACCACCAATAC
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	AGCAGATACAAACAAAGATATCAATATATAAGCTATA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CCTCTAAGTTGGACTGAAATTTTAGCTCTCTAAAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	CTCAAGACACATATTCTTTGCTTTTAGTAAAACATT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	ATTGTCGATTGTTCCTTGGTCGCCCTTGGCAACCAA
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	TTTTAATAGAATACGAAACTCTAATTATAACAAATATCACAAT
CTTTTAACTTCTTAGAAAGTTGAACTAATGGAAAC	AACAAAATGTTGAAAGTGTTGCTTTGTAATTGAAAT
CTTTTAACTTCTTAGAAAGTTGAACTATTAGAAGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019772.1\|WP_015217682.1\|163298_164198_+\|CRISPR-associated-protein,-Cmr4-family	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl\|CDD\|224255
NC_019772.1\|WP_042466342.1\|158095_158887_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|227751
NC_019772.1\|WP_015217680.1\|158959_162091_+\|CRISPR-associated-protein,-Crm2-family	cas10	cd09679_cas10_CAS-III	gnl\|CDD\|378863
NC_019772.1\|WP_015217681.1\|162094_163306_+\|CRISPR-associated-protein,-Cmr3	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	gnl\|CDD\|187879
NC_019772.1\|WP_015217671.1\|148498_149266_-\|DUF4384-domain-containing-protein	unknown	unknown	gnl\|CDD\|379557
NC_019772.1\|WP_015217672.1\|149603_151610_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_019772.1\|WP_015217664.1\|139893_140178_-\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217677.1\|157181_157478_+\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217673.1\|154305_155358_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_019772.1\|WP_015217670.1\|144443_148217_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|378942
NC_019772.1\|WP_015217675.1\|156118_156397_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_019772.1\|WP_171815842.1\|141567_142695_-\|ParB-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|275105
NC_019772.1\|WP_015217661.1\|137636_138659_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271177
NC_019772.1\|WP_015217667.1\|142691_143483_-\|ParA-family-protein	unknown	unknown	gnl\|CDD\|224113
NC_019772.1\|WP_015217678.1\|157617_157791_+\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217665.1\|140252_141194_-\|ParM/StbA-family-protein	unknown	unknown	gnl\|CDD\|212669
NC_019772.1\|WP_015217663.1\|139132_139798_+\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217676.1\|156579_156840_+\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217662.1\|138662_139130_+\|hypothetical-protein	unknown	unknown	unknown
NC_019772.1\|WP_015217674.1\|155584_155932_-\|four-helix-bundle-protein	unknown	unknown	gnl\|CDD\|274132

Protein	Function_ID	Function_description	E-value
NC_019772.1\|WP_042466342.1\|158095_158887_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|227751	COG5464, COG5464, Uncharacterized conserved protein [Function unknown].	6.00628e-38
NC_019772.1\|WP_015217680.1\|158959_162091_+\|CRISPR-associated-protein,-Crm2-family	gnl\|CDD\|378863	pfam12469, DUF3692, CRISPR-associated protein. This domain family is found in bacteria and archaea, and is typically between 101 and 138 amino acids in length. The proteins in this family are frequently annotated as CRISPR-associated proteins however there is little accompanying literature to confirm this.	9.15781e-36
NC_019772.1\|WP_015217671.1\|148498_149266_-\|DUF4384-domain-containing-protein	gnl\|CDD\|379557	pfam14326, DUF4384, Domain of unknown function (DUF4384). This presumed domain is functionally uncharacterized. This domain family is found in bacteria and archaea, and is approximately 80 amino acids in length.	1.90786e-18
NC_019772.1\|WP_015217672.1\|149603_151610_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.91752e-114
NC_019772.1\|WP_015217681.1\|162094_163306_+\|CRISPR-associated-protein,-Cmr3	gnl\|CDD\|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	3.94479e-38
NC_019772.1\|WP_015217674.1\|155584_155932_-\|four-helix-bundle-protein	gnl\|CDD\|274132	TIGR02436, S23_ribosomal_protein, four helix bundle protein. This family describes a protein of unknown function whose structure is a bundle of four long alpha helices. Some of the first members of this family were found encoded in the (atypically large) intervening sequence (IVS) of Leptospira 23S RNA, a region often present in the rRNA gene and removed during rRNA processing without re-ligation. However, this location is not conserved, and naming this protein as a 23S RNA protein is both confusing and inaccurate.	2.912e-31
NC_019772.1\|WP_015217670.1\|144443_148217_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	1.32895e-49
NC_019772.1\|WP_015217675.1\|156118_156397_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.34672e-29
NC_019772.1\|WP_171815842.1\|141567_142695_-\|ParB-N-terminal-domain-containing-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	5.59202e-15
NC_019772.1\|WP_015217661.1\|137636_138659_+\|site-specific-integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	4.8081e-31
NC_019772.1\|WP_015217667.1\|142691_143483_-\|ParA-family-protein	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	8.4971e-45
NC_019772.1\|WP_015217665.1\|140252_141194_-\|ParM/StbA-family-protein	gnl\|CDD\|212669	cd10227, ParM_like, Plasmid segregation protein ParM and similar proteins. ParM is a plasmid-encoded bacterial homolog of actin, which polymerizes into filaments similar to F-actin, and plays a vital role in plasmid segregation. ParM filaments segregate plasmids paired at midcell into the individual daughter cells. This subfamily also contains Thermoplasma acidophilum Ta0583, an active ATPase at physiological temperatures, which has a propensity to form filaments.	3.63692e-36
NC_019772.1\|WP_015217673.1\|154305_155358_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	2.87514e-66
NC_019772.1\|WP_015217682.1\|163298_164198_+\|CRISPR-associated-protein,-Cmr4-family	gnl\|CDD\|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.64701e-26

>NC_019772.1|WP_015217672.1|149603_151610_+|CRISPR-associated-endonuclease-Cas1
MFTIEQLYFAWSQVRVGSRSAGVDGISVDLFAASVDEQLTILLRQLQQESYHPSPAKGFYLTKKTGGKRLVGIPTVQDRIVQRLLLEELYFPLEETFVDCSYAYRPGRNIQQAVQQLFSYYQYHPTWIIKADIAQFFDNLCWALLLTNLEALQLESRILQLLEQQLKAGIIIAGKHINFGKGVLQGGIISGALANLYLTIFDRKCLSNGINLVRYGDDFAVACSSWKEANRILDKIIAWLGELYLTLQPEKTQIFAPNEELKFLGYRFANGKVYAPPPPEPKLEGEWLANASGTPYFRPKERPLKFVSRPPKACDISKPVSFPRAPISHLWQESMTTLYITDQGAYLSAKNQQFQVYYQQELRIKIPVVRVTNIVLFGCCNVSHGAVSVALHRRIPVMYLSQKGRYFGRLQTEGMAKVEYLARQVECSQNFEFTKKQAEAIVRAKLHNSRIMLMRLNRRVKSEKATQAIAQIELFMDKLPFSEDVNMLRGYEGIAATTYFQALGSLVTGKFTFEKRTKRPPTDPINSMLSLGYTLLSQNVHSLIQSVGLHTHFGNLHVPRDNHPALVSDLMEEFRALVVDSLVIYLVNRNLFTIDDFTSPDERNGVYFQPHALKKFLKHWEEKLQTEVTHPHTDCKLPYRRCIELQVREYIACLMGEVEVYRPMIWDK
>NC_019772.1|WP_015217671.1|148498_149266_-|DUF4384-domain-containing-protein
MAKRTLVASPKGIEKAKYALIRKNWTQQTLANDVHVASWATISKFFNGVPISYHIFIEICTMLELDWQDIAISSNLDITEIENQEQPLTPLAEIWQQLQSLGSSTEKMGLVLVKEETLAWSWQTNSIYEKSVSIGSHIRFEINLESSGYLLLIQKDTSGKVYCFCPSCFAPQAQLNQGKTVLPQEDAPMKSFKIEGEPGKEIIFAVITEEIPNLNWLPQENDEPLELTENHLSQLFNFISNHKDCRVMYTEYEVK
>NC_019772.1|WP_015217670.1|144443_148217_-|tetratricopeptide-repeat-protein
MEQIINQLIQLNLKVVELAGQGNLKHAMTVAQQAVNIGVNQQLTENSAYCDSLNNLAELHRIQGHYLEAKPLYLQALNIRKKLFGDEHPDVAQSLNNLAALYHAQGNYPAAAELFLEALELWKVCFGEEDFEVATTLNNLAEIYREQGQYLKAEQVHLEALTMRRSLFGDEHPDIAQSLTNLAALYTSTGRYSNAEEMHLEALAMKTRLFGEGHLDIASSLNNLGKVYDAQGRYLEAKSKFLEALEICQKNLGEEHPYIAFILSNIAGIYQEQGSYLDAEKKYLEVLSMRKRLLSEEHPDIANSLDHLGEVYLIQGNYLVAEQKYLEAYDLRKRLFSWEHPDIAESLSNLAVVFTYQGRYMEAKEQYSQALPMLEKLLGKKHLSIAHLLNNMAGLDEAQGDYSEAEQKYLKALEIQKNILGNEHPVIADTLNQIAALYRIQGRYSESEQLHLEGLAMRKRLLGEHHPFIATNLNNLAVLYDDLHQYDQSESLLIEALEIVKNVFGNEHPHVASSMNNLAVIYDFQGRYQEAEKLHLETLKLRILLLGEEHIQIANSLNNLGELYFSLGRYQEAEQKYVETLAMRKRLLGEEHPDVAFSLNNLATLLAATNRPDESLLCRIQGSKINNKMIRNIFAFSSESDRLAFLKKIRNDFDLFLSLVNKHLFNLDSAKLAAFDFVLQRKALTASALASQNAALYSGRYPQLQVQLHHLRDLNTQLIHLTFSVPQAGATGVNELPNYRENLAQLQVQYNYLQKQLALQVPEIQLSESNFDRQAIAKALPIDSILVEFVRFNVFDFPAIQAQGETQWHPPRYLAFVFRSGQPDTIQMVDLGAAETIDQLIQVFRLQASDYTEPTLAWSKNSQTPKLQIKPYNSTPAIKLSQALFHPIRDLVKDCRHLIIAPDSNLNLVPFQILPFGTTGSRLLMDEYIISYLSVGREILRSQVKPPTGSISAPLIIADPDFDLTADLTVDATTDRNTSNILRQPIPELLTTFITKGLSRAPGTRFLGESVAKKLPDAKLYLGAEALETRLTSSECPNIMLIATHGLFQSNSESQPVTKKGNLLSMEHLRKIKVENPMLRSGLALAGANTWLSGGKLPKDAGKGFLFAQDIASLDLWANELTVLSACDTARGDIQIGEGVFGLRRAFAVAGSKTLVMSLWPVPDKATALLMERFFDNLQSGMDRAEALHSAQNYIRNITVKELRKSALGLEVLKTLLDVRELTVDSKISCQEYDTPLKHPFYWGAWICQGETDRLVI
>NC_019772.1|WP_015217667.1|142691_143483_-|ParA-family-protein
MKQIVLSLIANAGGVGKTTLSVHIAYEMSRLGFDVVIIDLDPQRSLDVFCGLPSADVSTTLVKVLSKDFQGDWDLISVWEQSKTQVCQGHPLLAEIANELVIRKRGEYTLSDRLKKYPLPHNLVILDCPATLGMLNVNALAASTHILVPVQLEMKAISGSAELVEWCISTGDELQLEPRPPILGFVPSMYDDTVAMHRQYLEQLPEIAEHLHLKLYPKVRNSNEFKNASAHGLPLQKYRPKHPACRDFQQITDDLAALIQENK
>NC_019772.1|WP_171815842.1|141567_142695_-|ParB-N-terminal-domain-containing-protein
MIVALPKIANKFSGAIQKTEQEQKVAELQAEIERLRAAQSPDLENELQELREQLQNQSGESQIDLALIDPNPDQPRQTITPELIQAKARLLKKHGQISAVILIPQGNGRYTLLDGQLRTEAAKLLGWSTIRAVIAAMPKDLDQSALLTFLGFEDLNPLDKAEAVFKEVIKSTDLEMDEVATMLGTVIKRVERDGNSKELAKLMAVNADEQQQGLELLGITGREQSLLGVLLELGLNPSSVKANLMPMLYLSPDLKQAIREQGLKGAHALALATLSAKTLDISENQAASERMMATDEVLKKNLTVAETRELIRNIKTKYLKSQKKELKEIKTILQKVNGISEDLLTRASSKQLQEMRSLLQQKLAEVEKVIAVSEW
>NC_019772.1|WP_015217665.1|140252_141194_-|ParM/StbA-family-protein
MPNIHALQKIFPAGFDNGYGSLKLFVDGFEVVRIPSYISTAEMEDVPGRIVFDGAAYTVGESAFRTGYHFDRNTDHNENKIKNALLMLFGGLAHLPHRKAWHLKLVVSLHDIGLAENLKQALNGEYQPILAGKKSDVTLEIIKVVPEGMGALFGHQLPPKLTVLDFGNGTTLYSRYNQGKREVHTPYPAGVEVLIEDIAEKMKHLNGGKIGNASQIRFCLERGHTKYSRDIDIKDIYTSCLKDWYEKFLKKPVSLTLDANHQGDEIWAIGGGCLLPGFKKLLEKNGFKILDNPVEANAYGLLEMAKAMINKTL
>NC_019772.1|WP_015217664.1|139893_140178_-|hypothetical-protein
MTPEKVRIKDSYRERIFAESQQLDKSYLETLYFIIDCYFAFKKGAFPMQQVVHTPAFNPIATNQSPQDQLPSTPSPPENPKDADGETFTLDFDL
>NC_019772.1|WP_015217663.1|139132_139798_+|hypothetical-protein
MAIYRQLTIWDILDEMSEAPATSSLVTVWKCLDAELHDLPVGAQLSNAALAFTQIADILKVRAESLLQDVRDQNHPDGPVISNDIFAGLVRTTMQLDLDDLIETPVQQTFQPHGRHQFSYTGESGDSMVAPVEKAQVLAMLEEVTSLEDVYNLASDEDVQKWQSAIAHYLAQIKGEISLTKLQRMLQMPMVEVWLGLLLGEFVLEQRGDFYHSQNIWIINH
>NC_019772.1|WP_015217662.1|138662_139130_+|hypothetical-protein
MPKPLDPKCQLCAKLPTSKAKVLHGTEGDGCWNPQVCHNRRSFYRRRTEDNSAEIDAITVEPPTTYFAVLYLYKESGDKPLHALGAELWLGQKPICRLESIHCFGLTAGKIRTYTDQVLQAFAQQYSISLYQYKDMFEISPNHCPVRPCPLHPES
>NC_019772.1|WP_015217661.1|137636_138659_+|site-specific-integrase
MKSAELPPIKLIPIEDTGVIRKPKGNKISAKTTAPTDIRFVKVQEFLRSNNLAPNSRKLYERELKRFLAWTELHYHDLRPRHFGQYKEYLRDNVRTDTGKPLSKSSMNAGIAALKSFFKWMCYTYPDIIATNPTIGIKLEKVPLPPAQSLTPEQMQRVWSALELLGETKQRDTALVHILSHGLRAGEVVQLNAGSFDGKLLFLPDTKTNEPRLVPLRQDSREVVTEYLQWREQQGEVLTSLSPLMISHHASYQGERLSYHGIYFAIEKIGEIAEVEGLHPHSFRHTYATDLLLLGIDPTHARKLTGHQSERAFRRYTLRSEQEAAISAYYRAIGEETEVE
>NC_019772.1|WP_015217673.1|154305_155358_+|CRISPR-associated-endonuclease-Cas1
MSTIYITEQDANLQIQHHYLKVFHQQKQCVSLRISNVSQIILFGNITLPKEIIKVVVAHQIPVLYITPFGEIIGRLENTSQRQYKYLTCQRQWIRNRELKRATAESMIWAKLHNQHTFLQSWTRHHANYITQRALNYLTLLIDNLPIATFLNELREYSEEADKVYESAVTSIFSFYNVCSHINQKPINGFLNLGYQLLNQYIYTLLDSAGLHPNYAILSRNSDHELPLAWDLAAEFRAPIVDDCVLNFVRNFSHTNGNGKSQSRTILQRFLQHWEAQLRTFVIHPYAGEVSYRQCMDLQVREYIACLLGDAEYYRPLAFKHHPEEVKSQKIKVKREESEEVKSQKVKVLR
>NC_019772.1|WP_015217674.1|155584_155932_-|four-helix-bundle-protein
MTQDITERTFEFAVRVVKLCQVLEKQPGVTQTLAKQLLRSGTSIAANVEEARAGQSKADFIHKNAIALKEARETHYWLRLLIATEIISSNKLNELLQESEELKRILGAIIVKSKR
>NC_019772.1|WP_015217675.1|156118_156397_+|CRISPR-associated-endonuclease-Cas2
MFYLVCYDIVSDTRRNKVAKLLEAYGLRVQKSVFECVLDENQYTSLSKYLTRLVNKGEDQVRFYPMSAHTRCKIAVVGMQPEFVVDDAAFIV
>NC_019772.1|WP_015217676.1|156579_156840_+|hypothetical-protein
MNIKFRLIFTSKAQKQLDALAHQDRKQYHKAFQFLSKFGSSYRSLRTHRYQTKGGDIWSSSASMAKRFYWHFLEEHIIVVTHLDSH
>NC_019772.1|WP_015217677.1|157181_157478_+|hypothetical-protein
MPNPRPLQMRELRLISMYSHWEFGMTPQQFYSKWAVSYEQIALICSRSDSTVRGWFRNGRNRRYPTPNDLFHLGFMDFLLEHYEEIPEDIQSLLRFAC
>NC_019772.1|WP_015217678.1|157617_157791_+|hypothetical-protein
MTYFEQLHPWCIVRNLPSQDCIVVARFRRYNDATAYLQVLKRQANNVKFVVKFNSQT
>NC_019772.1|WP_042466342.1|158095_158887_+|Rpn-family-recombination-promoting-nuclease/putative-transposase
MYDNTCKFLAENFSTDFATWLLGKPISLTNLKPSELSVEPIRADSVIFLQSSQIILHIEFQTLPDDEIPFRMTDYRLRLYRKFPDKEIYQVVIYLTRSGLPLVFETSFVTGRLSHEFNVIRLWEQPTEVFQQYPGLLPLAVLTNTNDCSQTLSQVAKLIDNIEDRRIKSNITAATAIISGLALKKEVIQRLLRSEIMKESVIYQEILLEGKAEGKAEGKAEGKAEGKAEEKTRIALNMLHSGIAIDLIAQLTGLSIQQVQELQ
>NC_019772.1|WP_015217680.1|158959_162091_+|CRISPR-associated-protein,-Crm2-family
MNFYQRKLYALLQAPEFADWGDGVLSQLECLTNDHENLKAWWNGVNSNQKGEDAQAIASASDRVNLFYIERRENPPQVTVRHPISGQKQQVTTLPPPSNTPDISQIKNEIDPQKVFWWFWRFYPEILAATQPDALLFPAHTVIPDCPLHSHQSTVSALTGAMFPEEWEEGDSKTPYLLIFSFSPVQEFIKSSRKFLDFWAGSYLLHYLSSRLCWHIAQELGPDAVIVPSLWSQEIIDALIVQKYPDFGSDFERLQEDKKTPVERFTDKTSTSLSTAGFPNMITVLVPGKEAAQKLGTELKLKLTEEWVKIGEKVQLCIREKVIEYLKKQPTNIDKILEETFGDLTELSDEFLKPYRHELRLIQQESCWEWNKLWNEQLKHTWEPYWAAVPLGSPDLPLIKDKENSIFDETWIKVQQEIAYALIDLPSEAEANVYNTLNVGTWWGSLQQRLRICLIAVKNTRNWQIPTAPGERSTISGQFSAVHPRFNYTKFAEGAGTHASSMRLFWLLISQAFPGLFNGSEKLNALELTKRMAWVYGGVAEELGVKIVDESLLNEEDIKEFETDIDVKEIDYEQLIRFPNLSSIAAARFASERPDLLEKYWQNLNTLLKKYWDQQVTKKNDLETYKQQKRDFYSKTRRPFHISNTDAEIKIKLPHLRKSYNGVMFSGKWLADDMGLKGDAVAELKNLVDKAHSDTGFGDSSPADWWVIILADGDSMGSYVSGEKLKKYRFYVEEDTVDKTHDNFDNNLFNQFLQETTKRMGPATHVGLNRALLDFSNRLVPYLTEKRFCGRVIYSGGDDVKVVLPLEDLPEYILSLRAAWCGGEDPHQEFTNSRNDTENKVTGYWHPTDKVKGLPKRPHFTMGKDATMSAGVIIAHKSVPLPTVLESLWEAEGERAKKIPGKDGLCFRVIYGGGNQLEALMKGELLETWWEWVKEYETYQEKLSPLLYRLAEELPRRAAITDNYYLFSKAAKVIMDSRDSSKQLEPTFAKIEKWLDKWEDWVKSASQNNLEPIGTTPEDLGKILRFTAFWIDKRVERLKWGEK
>NC_019772.1|WP_015217681.1|162094_163306_+|CRISPR-associated-protein,-Cmr3
MHWYKITPLDLLLFRDCKPFSPGDGSWAKGLFPPMPITVFQAMRSLLPQTNHENRTQRHLSFLGPFLLDSQQTLWLPTPKDLVCLYPPGQDRKTATDNWSEILHLQTIPKDEEAWKHLAFDEEEIDPLVLNKKWDGNISPPKPWIKAEALFGYLRGQKNHSNCAQKDSEKPSTSWDQKDFHHNPWKTQVLPHIQMQPDKRQVKDADGYFTEVAVRLEDGWCFIAALSVDILARESIVRLGGEGHRALVSHLEPNDTLKGQLDFLLESDSEALLQAVRIPPDYSSTVPNFAYLLTPGLGLFEETSYRAYPQAWKEHLKGCATDKALLWGGVSTLRKDIDNNKTREESALLPQRAFVPPGTVYLFNHEVATNQQVLPNGDVNWLQTFRRLNYGKLLWGRRNLINE
>NC_019772.1|WP_015217682.1|163298_164198_+|CRISPR-associated-protein,-Cmr4-family
MSDFRTGYLYALAPVHCGGEGDLGNILDIVREVHTDFPYIPGSSLRGSVRWDVNSIDPAIADKLFGKELSADGQMGVHQVWFGDARLLWIPMRTMAMGNRNVFTWVSCHSLIRDHALLSGLPISDLPNHPVGTQAGSYYVADAQLQVSGFTNEQKQAIALAGDWQESLGNAIQSTWNNNRIVLADSDFQTLMEHSLWTQIRNKINKSEDNEDDSEGGAEIFWTDVCIPRDTILYYPWGYKLNKTNPIAQREHDCLMDVVTGLFQVGGQANVGRGWVQGWVTNNTLPVILNTNKLMQVEM

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_019772_1	1.1\|10053\|56\|NC_019772\|CRISPRCasFinder	10053-10108	56	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	10053-10108	0	1.0
NC_019772_2	2.1\|31620\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	31620-31654	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	31620-31654	0	1.0
NC_019772_2	2.2\|31692\|39\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	31692-31730	39	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	31692-31730	0	1.0
NC_019772_2	2.3\|31768\|34\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	31768-31801	34	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	31768-31801	0	1.0
NC_019772_2	2.4\|31839\|34\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	31839-31872	34	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	31839-31872	0	1.0
NC_019772_2	2.5\|31910\|39\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	31910-31948	39	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	31910-31948	0	1.0
NC_019772_2	2.6\|31986\|41\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	31986-32026	41	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	31986-32026	0	1.0
NC_019772_2	2.7\|32064\|42\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	32064-32105	42	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	32064-32105	0	1.0
NC_019772_2	2.8\|32143\|41\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	32143-32183	41	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	32143-32183	0	1.0
NC_019772_2	2.9\|32221\|34\|NC_019772\|CRISPRCasFinder,CRT	32221-32254	34	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	32221-32254	0	1.0
NC_019772_2	2.10\|32292\|33\|NC_019772\|CRISPRCasFinder,CRT	32292-32324	33	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	32292-32324	0	1.0
NC_019772_2	2.11\|32362\|34\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	32362-32395	34	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	32362-32395	0	1.0
NC_019772_2	2.12\|32433\|35\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	32433-32467	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	32433-32467	0	1.0
NC_019772_2	2.13\|32505\|37\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	32505-32541	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	32505-32541	0	1.0
NC_019772_2	2.14\|32579\|39\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	32579-32617	39	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	32579-32617	0	1.0
NC_019772_2	2.15\|32655\|37\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	32655-32691	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	32655-32691	0	1.0
NC_019772_2	2.16\|32729\|37\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	32729-32765	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	32729-32765	0	1.0
NC_019772_2	2.17\|32803\|38\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	32803-32840	38	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	32803-32840	0	1.0
NC_019772_2	2.18\|32878\|42\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	32878-32919	42	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	32878-32919	0	1.0
NC_019772_2	2.19\|32957\|39\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	32957-32995	39	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	32957-32995	0	1.0
NC_019772_2	2.20\|33033\|43\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	33033-33075	43	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	33033-33075	0	1.0
NC_019772_2	2.21\|33113\|34\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	33113-33146	34	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	33113-33146	0	1.0
NC_019772_2	2.22\|33184\|37\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	33184-33220	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	33184-33220	0	1.0
NC_019772_2	2.23\|33258\|37\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	33258-33294	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	33258-33294	0	1.0
NC_019772_2	2.24\|33332\|35\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	33332-33366	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	33332-33366	0	1.0
NC_019772_2	2.25\|33404\|37\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	33404-33440	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	33404-33440	0	1.0
NC_019772_2	2.26\|33478\|36\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	33478-33513	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	33478-33513	0	1.0
NC_019772_2	2.27\|33551\|37\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	33551-33587	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	33551-33587	0	1.0
NC_019772_2	2.28\|33625\|37\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	33625-33661	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	33625-33661	0	1.0
NC_019772_2	2.29\|33699\|36\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	33699-33734	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	33699-33734	0	1.0
NC_019772_2	2.30\|33772\|36\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	33772-33807	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	33772-33807	0	1.0
NC_019772_2	2.31\|33845\|35\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	33845-33879	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	33845-33879	0	1.0
NC_019772_2	2.32\|33917\|42\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	33917-33958	42	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	33917-33958	0	1.0
NC_019772_2	2.33\|33996\|36\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	33996-34031	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	33996-34031	0	1.0
NC_019772_2	2.34\|34069\|36\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	34069-34104	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	34069-34104	0	1.0
NC_019772_2	2.35\|34142\|36\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	34142-34177	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	34142-34177	0	1.0
NC_019772_2	2.36\|34215\|37\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	34215-34251	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	34215-34251	0	1.0
NC_019772_2	2.37\|34289\|40\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	34289-34328	40	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	34289-34328	0	1.0
NC_019772_2	2.38\|34366\|36\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	34366-34401	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	34366-34401	0	1.0
NC_019772_2	2.39\|34439\|35\|NC_019772\|CRISPRCasFinder,CRT,PILER-CR	34439-34473	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	34439-34473	0	1.0
NC_019772_3	3.1\|57709\|37\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	57709-57745	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	57709-57745	0	1.0
NC_019772_3	3.2\|57783\|34\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	57783-57816	34	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	57783-57816	0	1.0
NC_019772_3	3.3\|57854\|36\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	57854-57889	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	57854-57889	0	1.0
NC_019772_3	3.4\|57927\|37\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	57927-57963	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	57927-57963	0	1.0
NC_019772_3	3.5\|58001\|39\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	58001-58039	39	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	58001-58039	0	1.0
NC_019772_3	3.6\|58077\|39\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	58077-58115	39	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	58077-58115	0	1.0
NC_019772_3	3.7\|58153\|36\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	58153-58188	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	58153-58188	0	1.0
NC_019772_3	3.8\|58226\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	58226-58263	38	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	58226-58263	0	1.0
NC_019772_3	3.9\|58301\|36\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	58301-58336	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	58301-58336	0	1.0
NC_019772_3	3.10\|58374\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	58374-58408	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	58374-58408	0	1.0
NC_019772_3	3.11\|58446\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	58446-58480	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	58446-58480	0	1.0
NC_019772_3	3.12\|58518\|39\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	58518-58556	39	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	58518-58556	0	1.0
NC_019772_3	3.13\|58594\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	58594-58631	38	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	58594-58631	0	1.0
NC_019772_3	3.14\|58669\|40\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	58669-58708	40	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	58669-58708	0	1.0
NC_019772_3	3.15\|58746\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	58746-58780	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	58746-58780	0	1.0
NC_019772_3	3.16\|58818\|36\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	58818-58853	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	58818-58853	0	1.0
NC_019772_3	3.17\|58891\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	58891-58925	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	58891-58925	0	1.0
NC_019772_3	3.18\|58963\|34\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	58963-58996	34	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	58963-58996	0	1.0
NC_019772_3	3.19\|59034\|42\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59034-59075	42	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	59034-59075	0	1.0
NC_019772_3	3.20\|59113\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59113-59150	38	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	59113-59150	0	1.0
NC_019772_3	3.21\|59188\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59188-59222	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	59188-59222	0	1.0
NC_019772_3	3.22\|59260\|43\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59260-59302	43	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	59260-59302	0	1.0
NC_019772_3	3.23\|59340\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59340-59377	38	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	59340-59377	0	1.0
NC_019772_3	3.24\|59415\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59415-59452	38	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	59415-59452	0	1.0
NC_019772_3	3.25\|59490\|36\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59490-59525	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	59490-59525	0	1.0
NC_019772_3	3.26\|59563\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59563-59600	38	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	59563-59600	0	1.0
NC_019772_3	3.27\|59638\|37\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59638-59674	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	59638-59674	0	1.0
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	59712-59749	0	1.0
NC_019772_3	3.29\|59787\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59787-59821	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	59787-59821	0	1.0
NC_019772_3	3.30\|59859\|36\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59859-59894	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	59859-59894	0	1.0
NC_019772_3	3.31\|59932\|36\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59932-59967	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	59932-59967	0	1.0
NC_019772_3	3.32\|60005\|37\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	60005-60041	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	60005-60041	0	1.0
NC_019772_3	3.33\|60079\|33\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	60079-60111	33	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	60079-60111	0	1.0
NC_019772_3	3.34\|60149\|34\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	60149-60182	34	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	60149-60182	0	1.0
NC_019772_3	3.35\|60220\|37\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	60220-60256	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	60220-60256	0	1.0
NC_019772_3	3.36\|60294\|37\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	60294-60330	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	60294-60330	0	1.0
NC_019772_3	3.37\|60368\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	60368-60405	38	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	60368-60405	0	1.0
NC_019772_3	3.38\|60443\|36\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	60443-60478	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	60443-60478	0	1.0
NC_019772_3	3.39\|60516\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	60516-60550	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	60516-60550	0	1.0
NC_019772_3	3.40\|60588\|36\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	60588-60623	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	60588-60623	0	1.0
NC_019772_3	3.41\|60661\|39\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	60661-60699	39	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	60661-60699	0	1.0
NC_019772_3	3.42\|60737\|37\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	60737-60773	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	60737-60773	0	1.0
NC_019772_3	3.43\|60811\|41\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	60811-60851	41	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	60811-60851	0	1.0
NC_019772_3	3.44\|60889\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	60889-60923	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	60889-60923	0	1.0
NC_019772_3	3.45\|60961\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	60961-60995	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	60961-60995	0	1.0
NC_019772_3	3.46\|61033\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	61033-61070	38	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	61033-61070	0	1.0
NC_019772_3	3.47\|61108\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	61108-61142	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	61108-61142	0	1.0
NC_019772_4	4.1\|90853\|51\|NC_019772\|CRISPRCasFinder	90853-90903	51	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	90853-90903	0	1.0
NC_019772_5	5.1\|151856\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	151856-151890	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	151856-151890	0	1.0
NC_019772_5	5.2\|151926\|39\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	151926-151964	39	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	151926-151964	0	1.0
NC_019772_5	5.3\|152000\|36\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	152000-152035	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	152000-152035	0	1.0
NC_019772_5	5.4\|152071\|37\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	152071-152107	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	152071-152107	0	1.0
NC_019772_5	5.5\|152143\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	152143-152180	38	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	152143-152180	0	1.0
NC_019772_5	5.6\|152216\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	152216-152250	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	152216-152250	0	1.0
NC_019772_5	5.7\|152286\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	152286-152323	38	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	152286-152323	0	1.0
NC_019772_5	5.8\|152359\|39\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	152359-152397	39	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	152359-152397	0	1.0
NC_019772_5	5.9\|152433\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	152433-152467	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	152433-152467	0	1.0
NC_019772_5	5.10\|152503\|37\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	152503-152539	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	152503-152539	0	1.0
NC_019772_5	5.11\|152575\|34\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	152575-152608	34	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	152575-152608	0	1.0
NC_019772_5	5.12\|152644\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	152644-152681	38	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	152644-152681	0	1.0
NC_019772_5	5.13\|152717\|39\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	152717-152755	39	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	152717-152755	0	1.0
NC_019772_5	5.14\|152791\|39\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	152791-152829	39	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	152791-152829	0	1.0
NC_019772_5	5.15\|152865\|40\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	152865-152904	40	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	152865-152904	0	1.0
NC_019772_5	5.16\|152940\|37\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	152940-152976	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	152940-152976	0	1.0
NC_019772_5	5.17\|153012\|36\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	153012-153047	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	153012-153047	0	1.0
NC_019772_5	5.18\|153083\|39\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	153083-153121	39	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	153083-153121	0	1.0
NC_019772_5	5.19\|153157\|39\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	153157-153195	39	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	153157-153195	0	1.0
NC_019772_5	5.20\|153231\|39\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	153231-153269	39	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	153231-153269	0	1.0
NC_019772_5	5.21\|153305\|41\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	153305-153345	41	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	153305-153345	0	1.0
NC_019772_5	5.22\|153381\|37\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	153381-153417	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	153381-153417	0	1.0
NC_019772_5	5.23\|153453\|37\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	153453-153489	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	153453-153489	0	1.0
NC_019772_5	5.24\|153525\|41\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	153525-153565	41	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	153525-153565	0	1.0
NC_019772_5	5.25\|153601\|37\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	153601-153637	37	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	153601-153637	0	1.0
NC_019772_5	5.26\|153673\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	153673-153707	35	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	153673-153707	0	1.0
NC_019772_5	5.27\|153743\|36\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	153743-153778	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	153743-153778	0	1.0
NC_019772_5	5.28\|153814\|36\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	153814-153849	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	153814-153849	0	1.0
NC_019772_5	5.29\|153885\|43\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	153885-153927	43	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	153885-153927	0	1.0
NC_019772_5	5.30\|153963\|36\|NC_019772\|CRISPRCasFinder,CRT	153963-153998	36	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	153963-153998	0	1.0
NC_019772_3	3.20\|59113\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59113-59150	38	MG209611	Aphanizomenon phage vB_AphaS-CL131, complete genome	71264-71301	6	0.842
NC_019772_2	2.4\|31839\|34\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	31839-31872	34	NZ_CP043832	Bacillus sp. BS98 plasmid unnamed2	122490-122523	8	0.765
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP034093	Acinetobacter baumannii strain A52 plasmid pA52-1, complete sequence	103534-103571	8	0.789
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP023025	Acinetobacter baumannii strain 10324 plasmid pAba10324c, complete sequence	43440-43477	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP041590	Acinetobacter baumannii strain J9 plasmid pJ9-3, complete sequence	47957-47994	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP039519	Acinetobacter baumannii strain TG22653 plasmid pTG22653, complete sequence	35758-35795	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP033864	Acinetobacter sp. FDAARGOS_560 plasmid unnamed2	58567-58604	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP010398	Acinetobacter baumannii strain 6200 plasmid p6200-114.848kb, complete sequence	41814-41851	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP015484	Acinetobacter baumannii strain ORAB01 plasmid pORAB01-1, complete sequence	43874-43911	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP018333	Acinetobacter baumannii strain A1296 isolate A1296 plasmid pA1296_1, complete sequence	105820-105857	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	CP031744	Acinetobacter baumannii WM99c plasmid pWM99c-2, complete sequence	43875-43912	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP050905	Acinetobacter baumannii strain DT-Ab057 plasmid unnamed1, complete sequence	49769-49806	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NC_020524	Acinetobacter baumannii MDR-TJ plasmid pABTJ2, complete sequence	43875-43912	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP021327	Acinetobacter baumannii strain XH386 plasmid pXH386, complete sequence	107348-107385	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP038645	Acinetobacter baumannii strain ACN21 plasmid unnamed1, complete sequence	40398-40435	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	CP033517	Acinetobacter baumannii strain 2008S11-069 plasmid p2008S11-069-1, complete sequence	73443-73480	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP016301	Acinetobacter baumannii strain CMC-CR-MDR-Ab66 plasmid pCMCVTAb1-Ab66, complete sequence	5687-5724	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP016296	Acinetobacter baumannii strain CMC-CR-MDR-Ab4 plasmid pCMCVTAb1-Ab4, complete sequence	5687-5724	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP016299	Acinetobacter baumannii strain CMC-MDR-Ab59 plasmid pCMCVTAb1-Ab59, complete sequence	5687-5724	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP024125	Acinetobacter baumannii strain AYP-A2 plasmid pAYP-A2, complete sequence	43707-43744	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP026128	Acinetobacter baumannii strain ABNIH28 plasmid pABA-1fe1, complete sequence	55501-55538	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP020585	Acinetobacter baumannii strain CBA7 plasmid pCBA7_1, complete sequence	52474-52511	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NC_023031	Acinetobacter baumannii ZW85-1 plasmid ZW85p2, complete sequence	59796-59833	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_MK386680	Acinetobacter baumannii strain ABAY04001 plasmid pABAY04001_1A, complete sequence	92073-92110	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP018257	Acinetobacter baumannii strain AF-673 plasmid pAF-673, complete sequence	68798-68835	9	0.763
NC_019772_3	3.28\|59712\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59712-59749	38	NZ_CP010780	Acinetobacter baumannii strain XH386 plasmid pAB386, complete sequence	13375-13412	9	0.763
NC_019772_3	3.47\|61108\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	61108-61142	35	MN694447	Marine virus AFVG_250M387, complete genome	54288-54322	10	0.714
NC_019772_3	3.47\|61108\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	61108-61142	35	MN694065	Marine virus AFVG_250M443, complete genome	2312-2346	10	0.714
NC_019772_2	2.4\|31839\|34\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	31839-31872	34	MN693811	Marine virus AFVG_250M463, complete genome	25807-25840	11	0.676
NC_019772_3	3.24\|59415\|38\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59415-59452	38	NC_019544	Deep-sea thermophilic phage D6E, complete genome	15598-15635	11	0.711
NC_019772_3	3.29\|59787\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59787-59821	35	NZ_KT897276	Clostridium botulinum strain INGR16-02E1 plasmid pINGR16-02E1, complete sequence	114413-114447	11	0.686
NC_019772_3	3.29\|59787\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59787-59821	35	NZ_KT897280	Clostridium botulinum strain FI1111E1 plasmid pFI1111E1, complete sequence	124139-124173	11	0.686
NC_019772_3	3.29\|59787\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59787-59821	35	NZ_KT897275	Clostridium botulinum strain IFR 12/29 plasmid p12/29, complete sequence	119343-119377	11	0.686
NC_019772_3	3.29\|59787\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59787-59821	35	NZ_KT897277	Clostridium botulinum strain ST0210E1 plasmid pST0210E1, complete sequence	114413-114447	11	0.686
NC_019772_3	3.29\|59787\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59787-59821	35	NZ_KT897278	Clostridium botulinum strain FWSKR40E1 plasmid pFWSKR40E1, complete sequence	121564-121598	11	0.686
NC_019772_3	3.29\|59787\|35\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	59787-59821	35	NZ_KT897279	Clostridium botulinum strain SWKR38E2 plasmid pSWKR38E2, complete sequence	122700-122734	11	0.686
NC_019772_5	5.2\|151926\|39\|NC_019772\|PILER-CR,CRISPRCasFinder,CRT	151926-151964	39	NC_017064	Helicobacter pylori ELS37 plasmid pHPELS37, complete sequence	1023-1061	11	0.718

1. spacer 1.1|10053|56|NC_019772|CRISPRCasFinder matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

caacaagctattatttgttgacaagcattaatttttattttcatcaaaataaactt	CRISPR spacer
caacaagctattatttgttgacaagcattaatttttattttcatcaaaataaactt	Protospacer
********************************************************

2. spacer 2.1|31620|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

atacgcgctgcgagtgcggtatgtgtggtaagtga	CRISPR spacer
atacgcgctgcgagtgcggtatgtgtggtaagtga	Protospacer
***********************************

3. spacer 2.2|31692|39|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

atagacaagaactagaacgtaaagagattatctggaaaa	CRISPR spacer
atagacaagaactagaacgtaaagagattatctggaaaa	Protospacer
***************************************

4. spacer 2.3|31768|34|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

cttactcctactattccttactttgtttttccat	CRISPR spacer
cttactcctactattccttactttgtttttccat	Protospacer
**********************************

5. spacer 2.4|31839|34|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ataatttagatccatttatttatcgttggaaatg	CRISPR spacer
ataatttagatccatttatttatcgttggaaatg	Protospacer
**********************************

6. spacer 2.5|31910|39|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tcgatagtgaatcgtgggatatttttgttcacaagaaac	CRISPR spacer
tcgatagtgaatcgtgggatatttttgttcacaagaaac	Protospacer
***************************************

7. spacer 2.6|31986|41|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

actgatatccagcaagtctcgtgggcttcatcacaaataat	CRISPR spacer
actgatatccagcaagtctcgtgggcttcatcacaaataat	Protospacer
*****************************************

8. spacer 2.7|32064|42|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttggcaagacatcctacaatatagataccttttgttttgttg	CRISPR spacer
ttggcaagacatcctacaatatagataccttttgttttgttg	Protospacer
******************************************

9. spacer 2.8|32143|41|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttgggcgtagcttctgagaagctagaaattccttcagatgt	CRISPR spacer
ttgggcgtagcttctgagaagctagaaattccttcagatgt	Protospacer
*****************************************

10. spacer 2.9|32221|34|NC_019772|CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aaattattgcgatcgcgaaggcaagaaatatgaa	CRISPR spacer
aaattattgcgatcgcgaaggcaagaaatatgaa	Protospacer
**********************************

11. spacer 2.10|32292|33|NC_019772|CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

caataactgatattcctaaactccacaaataaa	CRISPR spacer
caataactgatattcctaaactccacaaataaa	Protospacer
*********************************

12. spacer 2.11|32362|34|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tatttgaccttagtgcctggtaagtggggtgcaa	CRISPR spacer
tatttgaccttagtgcctggtaagtggggtgcaa	Protospacer
**********************************

13. spacer 2.12|32433|35|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttctgagcttttacaactccggccgcgattaaagg	CRISPR spacer
ttctgagcttttacaactccggccgcgattaaagg	Protospacer
***********************************

14. spacer 2.13|32505|37|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

taaaaaaaatcatggctaccacacaaactgctcttaa	CRISPR spacer
taaaaaaaatcatggctaccacacaaactgctcttaa	Protospacer
*************************************

15. spacer 2.14|32579|39|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

gatataactttaatgctttaatgtagacgatactccttt	CRISPR spacer
gatataactttaatgctttaatgtagacgatactccttt	Protospacer
***************************************

16. spacer 2.15|32655|37|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aactaaactaccagaatctgtacttatatctaggaga	CRISPR spacer
aactaaactaccagaatctgtacttatatctaggaga	Protospacer
*************************************

17. spacer 2.16|32729|37|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tcaatttgatagctgccaggaatcggacaaggggcag	CRISPR spacer
tcaatttgatagctgccaggaatcggacaaggggcag	Protospacer
*************************************

18. spacer 2.17|32803|38|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttcattaaattgtcgaggttcagttttgattgataaat	CRISPR spacer
ttcattaaattgtcgaggttcagttttgattgataaat	Protospacer
**************************************

19. spacer 2.18|32878|42|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

catcaacctcaattaaattaagggtatcttcaactttaaaac	CRISPR spacer
catcaacctcaattaaattaagggtatcttcaactttaaaac	Protospacer
******************************************

20. spacer 2.19|32957|39|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ctgatgaaaatcataattgctgataacctgtgtagggat	CRISPR spacer
ctgatgaaaatcataattgctgataacctgtgtagggat	Protospacer
***************************************

21. spacer 2.20|33033|43|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

gggggctaacttatctagggttaggtttttggatcaatgctaa	CRISPR spacer
gggggctaacttatctagggttaggtttttggatcaatgctaa	Protospacer
*******************************************

22. spacer 2.21|33113|34|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ctatctccaatcgagtcttatcaaatcttgactg	CRISPR spacer
ctatctccaatcgagtcttatcaaatcttgactg	Protospacer
**********************************

23. spacer 2.22|33184|37|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tatctagtctgtaaaaaagtctggtacatcgactggt	CRISPR spacer
tatctagtctgtaaaaaagtctggtacatcgactggt	Protospacer
*************************************

24. spacer 2.23|33258|37|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ccagataaggtttgatagcaaaggggagtttaatctt	CRISPR spacer
ccagataaggtttgatagcaaaggggagtttaatctt	Protospacer
*************************************

25. spacer 2.24|33332|35|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aaggcaaaattcatattattcaactccgatgctat	CRISPR spacer
aaggcaaaattcatattattcaactccgatgctat	Protospacer
***********************************

26. spacer 2.25|33404|37|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aacctgttacaggttatgctagataggtactagcagt	CRISPR spacer
aacctgttacaggttatgctagataggtactagcagt	Protospacer
*************************************

27. spacer 2.26|33478|36|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

attccattaaaagaagctgccaaaaaactgaactat	CRISPR spacer
attccattaaaagaagctgccaaaaaactgaactat	Protospacer
************************************

28. spacer 2.27|33551|37|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tattgttgcaactgtctggtattgggatagagatgaa	CRISPR spacer
tattgttgcaactgtctggtattgggatagagatgaa	Protospacer
*************************************

29. spacer 2.28|33625|37|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ctgtagacgacataattgagtctccagacttttggat	CRISPR spacer
ctgtagacgacataattgagtctccagacttttggat	Protospacer
*************************************

30. spacer 2.29|33699|36|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tttacagggaatcttaaaagaaattcataaaatcat	CRISPR spacer
tttacagggaatcttaaaagaaattcataaaatcat	Protospacer
************************************

31. spacer 2.30|33772|36|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tttttcttaaattagaaatagaatttataacatcta	CRISPR spacer
tttttcttaaattagaaatagaatttataacatcta	Protospacer
************************************

32. spacer 2.31|33845|35|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tttcaacaaaggttttttgttccgtttcattgtca	CRISPR spacer
tttcaacaaaggttttttgttccgtttcattgtca	Protospacer
***********************************

33. spacer 2.32|33917|42|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tctcgaaccggtcaagcgatcgctaaagaaaaacttattaat	CRISPR spacer
tctcgaaccggtcaagcgatcgctaaagaaaaacttattaat	Protospacer
******************************************

34. spacer 2.33|33996|36|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

gtagcttacaaaaacatcttaggcaatataaaagcc	CRISPR spacer
gtagcttacaaaaacatcttaggcaatataaaagcc	Protospacer
************************************

35. spacer 2.34|34069|36|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttttaaggtgcaacgagactgggtatataccgttga	CRISPR spacer
ttttaaggtgcaacgagactgggtatataccgttga	Protospacer
************************************

36. spacer 2.35|34142|36|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

agtgttccctttccctggaacaaccaagcctatcac	CRISPR spacer
agtgttccctttccctggaacaaccaagcctatcac	Protospacer
************************************

37. spacer 2.36|34215|37|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttgaagttgtgccaaacttttccgaatccggctattt	CRISPR spacer
ttgaagttgtgccaaacttttccgaatccggctattt	Protospacer
*************************************

38. spacer 2.37|34289|40|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tagagtcttacatagcctcgaattttgtgtctatagatga	CRISPR spacer
tagagtcttacatagcctcgaattttgtgtctatagatga	Protospacer
****************************************

39. spacer 2.38|34366|36|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

attcactggacagatgcaacagattttaaggttaat	CRISPR spacer
attcactggacagatgcaacagattttaaggttaat	Protospacer
************************************

40. spacer 2.39|34439|35|NC_019772|CRISPRCasFinder,CRT,PILER-CR matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ctagaaaatagtaacgttttaaagccagaagaggt	CRISPR spacer
ctagaaaatagtaacgttttaaagccagaagaggt	Protospacer
***********************************

41. spacer 3.1|57709|37|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aatcaaattcagctacgtacttcgcgaagctttctaa	CRISPR spacer
aatcaaattcagctacgtacttcgcgaagctttctaa	Protospacer
*************************************

42. spacer 3.2|57783|34|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tcttatcgtcttgttctgcggttagaccgatgct	CRISPR spacer
tcttatcgtcttgttctgcggttagaccgatgct	Protospacer
**********************************

43. spacer 3.3|57854|36|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

gctacaatcacacagaaaaaatttttattgacctaa	CRISPR spacer
gctacaatcacacagaaaaaatttttattgacctaa	Protospacer
************************************

44. spacer 3.4|57927|37|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

attagatcagaatattcatctgtggcagatgagccaa	CRISPR spacer
attagatcagaatattcatctgtggcagatgagccaa	Protospacer
*************************************

45. spacer 3.5|58001|39|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

gtttcaccactgctaccagaccaactaccttttttcttg	CRISPR spacer
gtttcaccactgctaccagaccaactaccttttttcttg	Protospacer
***************************************

46. spacer 3.6|58077|39|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aagcgtaaatatttcccgtatgaattggggtagggtttc	CRISPR spacer
aagcgtaaatatttcccgtatgaattggggtagggtttc	Protospacer
***************************************

47. spacer 3.7|58153|36|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aagacaatgcaggaattaaaaggatacacaccaaca	CRISPR spacer
aagacaatgcaggaattaaaaggatacacaccaaca	Protospacer
************************************

48. spacer 3.8|58226|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

gctttgtctatagtttataagggttagagtgatccaaa	CRISPR spacer
gctttgtctatagtttataagggttagagtgatccaaa	Protospacer
**************************************

49. spacer 3.9|58301|36|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aattcttcttgtttctggatgttatagaatttagat	CRISPR spacer
aattcttcttgtttctggatgttatagaatttagat	Protospacer
************************************

50. spacer 3.10|58374|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ctctttttatcaatcttcctctgtaatcttttgat	CRISPR spacer
ctctttttatcaatcttcctctgtaatcttttgat	Protospacer
***********************************

51. spacer 3.11|58446|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

gttctggaggaggaggatcagggggtgatgcgagt	CRISPR spacer
gttctggaggaggaggatcagggggtgatgcgagt	Protospacer
***********************************

52. spacer 3.12|58518|39|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tcaacgcatatggcgcgcaaggtacaagtttctggacga	CRISPR spacer
tcaacgcatatggcgcgcaaggtacaagtttctggacga	Protospacer
***************************************

53. spacer 3.13|58594|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttcagttggaatacaacaataggcgaagtccagcttta	CRISPR spacer
ttcagttggaatacaacaataggcgaagtccagcttta	Protospacer
**************************************

54. spacer 3.14|58669|40|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tatcttactatagatacgactatagatagtgatatagggg	CRISPR spacer
tatcttactatagatacgactatagatagtgatatagggg	Protospacer
****************************************

55. spacer 3.15|58746|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tcaatcaagtacaatggtggcaatatctcttaaat	CRISPR spacer
tcaatcaagtacaatggtggcaatatctcttaaat	Protospacer
***********************************

56. spacer 3.16|58818|36|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

accctcgctgtctggcaattctactagatgagctat	CRISPR spacer
accctcgctgtctggcaattctactagatgagctat	Protospacer
************************************

57. spacer 3.17|58891|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tagtcaggtagctgctgattaccgttttgtgcgta	CRISPR spacer
tagtcaggtagctgctgattaccgttttgtgcgta	Protospacer
***********************************

58. spacer 3.18|58963|34|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

atcctactaaccgatggcgaagatctcaacataa	CRISPR spacer
atcctactaaccgatggcgaagatctcaacataa	Protospacer
**********************************

59. spacer 3.19|59034|42|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

gttaaatctctgattccaagctctctgttattcgctgctata	CRISPR spacer
gttaaatctctgattccaagctctctgttattcgctgctata	Protospacer
******************************************

60. spacer 3.20|59113|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

taatatctgggggattgagtgcgatcgccaaatagcag	CRISPR spacer
taatatctgggggattgagtgcgatcgccaaatagcag	Protospacer
**************************************

61. spacer 3.21|59188|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aggaatttaactcattttgtaggttagtttcttca	CRISPR spacer
aggaatttaactcattttgtaggttagtttcttca	Protospacer
***********************************

62. spacer 3.22|59260|43|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tcttccaaaaatcaaaagatattcttgctgacaagcaatcaat	CRISPR spacer
tcttccaaaaatcaaaagatattcttgctgacaagcaatcaat	Protospacer
*******************************************

63. spacer 3.23|59340|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tacactaaaaaaataatcccccaaaccgtcgtaaccgg	CRISPR spacer
tacactaaaaaaataatcccccaaaccgtcgtaaccgg	Protospacer
**************************************

64. spacer 3.24|59415|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

gagaaaatgacagaagaacaagcaaaagaacttttaat	CRISPR spacer
gagaaaatgacagaagaacaagcaaaagaacttttaat	Protospacer
**************************************

65. spacer 3.25|59490|36|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttggcgtaaatgtagcctattaaatccccctcaagc	CRISPR spacer
ttggcgtaaatgtagcctattaaatccccctcaagc	Protospacer
************************************

66. spacer 3.26|59563|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aacaatggttcgggtttctctatgtcttgacccttgcc	CRISPR spacer
aacaatggttcgggtttctctatgtcttgacccttgcc	Protospacer
**************************************

67. spacer 3.27|59638|37|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

atatcgttatatagtaatacgcgaggatagcgatata	CRISPR spacer
atatcgttatatagtaatacgcgaggatagcgatata	Protospacer
*************************************

68. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
gccaatttcagaaagattgccaacaaatgatttaagaa	Protospacer
**************************************

69. spacer 3.29|59787|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttaaaatcagccatgatctttaataattaaattta	CRISPR spacer
ttaaaatcagccatgatctttaataattaaattta	Protospacer
***********************************

70. spacer 3.30|59859|36|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

atttcttccagggttggtttatggtggaaaaccctg	CRISPR spacer
atttcttccagggttggtttatggtggaaaaccctg	Protospacer
************************************

71. spacer 3.31|59932|36|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

cagagaatccaaacatctttagaatcaccgccaacc	CRISPR spacer
cagagaatccaaacatctttagaatcaccgccaacc	Protospacer
************************************

72. spacer 3.32|60005|37|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aaaagcttgttgtttgtcaagatgaatgtcgcagaaa	CRISPR spacer
aaaagcttgttgtttgtcaagatgaatgtcgcagaaa	Protospacer
*************************************

73. spacer 3.33|60079|33|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

taaatgtactatgctgctctggcatttaaaata	CRISPR spacer
taaatgtactatgctgctctggcatttaaaata	Protospacer
*********************************

74. spacer 3.34|60149|34|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttaagaatatgactaattattgcaatacaggtga	CRISPR spacer
ttaagaatatgactaattattgcaatacaggtga	Protospacer
**********************************

75. spacer 3.35|60220|37|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

caactatcgaagcggtttctttctgctaagtccaatg	CRISPR spacer
caactatcgaagcggtttctttctgctaagtccaatg	Protospacer
*************************************

76. spacer 3.36|60294|37|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

caaacagccatagacaacactattgccaccgttggcg	CRISPR spacer
caaacagccatagacaacactattgccaccgttggcg	Protospacer
*************************************

77. spacer 3.37|60368|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

gagatacaaagcaatctgagaagtctttgccacctata	CRISPR spacer
gagatacaaagcaatctgagaagtctttgccacctata	Protospacer
**************************************

78. spacer 3.38|60443|36|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

taataagcttcctttatcgatctaaaagcttcagta	CRISPR spacer
taataagcttcctttatcgatctaaaagcttcagta	Protospacer
************************************

79. spacer 3.39|60516|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

taacataaacccataacccttgtcaagcatgactt	CRISPR spacer
taacataaacccataacccttgtcaagcatgactt	Protospacer
***********************************

80. spacer 3.40|60588|36|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttcttgccatatctgcaatagcattagcaatcaaga	CRISPR spacer
ttcttgccatatctgcaatagcattagcaatcaaga	Protospacer
************************************

81. spacer 3.41|60661|39|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

acaatactcgcagacttagaagatttttcaagcctagcg	CRISPR spacer
acaatactcgcagacttagaagatttttcaagcctagcg	Protospacer
***************************************

82. spacer 3.42|60737|37|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aaaagttagttgctaaagaagttggtgcggctgtcgg	CRISPR spacer
aaaagttagttgctaaagaagttggtgcggctgtcgg	Protospacer
*************************************

83. spacer 3.43|60811|41|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

atgctatcctattaattgccttatcaaaatagtagtgattg	CRISPR spacer
atgctatcctattaattgccttatcaaaatagtagtgattg	Protospacer
*****************************************

84. spacer 3.44|60889|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aatgtaaaatagacaacatgaatccatcattgtag	CRISPR spacer
aatgtaaaatagacaacatgaatccatcattgtag	Protospacer
***********************************

85. spacer 3.45|60961|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

attatctatctaattgattatgttgtatgtaacta	CRISPR spacer
attatctatctaattgattatgttgtatgtaacta	Protospacer
***********************************

86. spacer 3.46|61033|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tcaatcaagtcccaacataaaggcactagttatcaaaa	CRISPR spacer
tcaatcaagtcccaacataaaggcactagttatcaaaa	Protospacer
**************************************

87. spacer 3.47|61108|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aatccaattaagaacagaaataaataactcatctt	CRISPR spacer
aatccaattaagaacagaaataaataactcatctt	Protospacer
***********************************

88. spacer 4.1|90853|51|NC_019772|CRISPRCasFinder matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aaaaatcgaagttcttaatctttcacaaccgggttaggtgctagttcccgc	CRISPR spacer
aaaaatcgaagttcttaatctttcacaaccgggttaggtgctagttcccgc	Protospacer
***************************************************

89. spacer 5.1|151856|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

gaggaaacagcatgaataaaatgggtgctgaaact	CRISPR spacer
gaggaaacagcatgaataaaatgggtgctgaaact	Protospacer
***********************************

90. spacer 5.2|151926|39|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

gttttctgttttgaatctaaaaaagaaatgattttctct	CRISPR spacer
gttttctgttttgaatctaaaaaagaaatgattttctct	Protospacer
***************************************

91. spacer 5.3|152000|36|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tacatcaatgtaactgttccattgttgttagttgta	CRISPR spacer
tacatcaatgtaactgttccattgttgttagttgta	Protospacer
************************************

92. spacer 5.4|152071|37|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tgtcttttccattcaagataacccaaaatagaaagcg	CRISPR spacer
tgtcttttccattcaagataacccaaaatagaaagcg	Protospacer
*************************************

93. spacer 5.5|152143|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttatctcaatttctcttggtaccaatactgcatcatta	CRISPR spacer
ttatctcaatttctcttggtaccaatactgcatcatta	Protospacer
**************************************

94. spacer 5.6|152216|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ctcaaataaaacaacttccatcggctttttgtagt	CRISPR spacer
ctcaaataaaacaacttccatcggctttttgtagt	Protospacer
***********************************

95. spacer 5.7|152286|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttggttggaaacctgaatgcgatactgagttccatgtt	CRISPR spacer
ttggttggaaacctgaatgcgatactgagttccatgtt	Protospacer
**************************************

96. spacer 5.8|152359|39|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

cttgcgaatttttgagcctttgtaaggctgaagctattt	CRISPR spacer
cttgcgaatttttgagcctttgtaaggctgaagctattt	Protospacer
***************************************

97. spacer 5.9|152433|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

cggcgagagccgcatgggtggcaactccgactaat	CRISPR spacer
cggcgagagccgcatgggtggcaactccgactaat	Protospacer
***********************************

98. spacer 5.10|152503|37|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aagcttcttcaaccatgcagttacagtgttgacactt	CRISPR spacer
aagcttcttcaaccatgcagttacagtgttgacactt	Protospacer
*************************************

99. spacer 5.11|152575|34|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tttttttctaactgtgtaaatttccacaacttga	CRISPR spacer
tttttttctaactgtgtaaatttccacaacttga	Protospacer
**********************************

100. spacer 5.12|152644|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tttcagactgagactgagccaaaactggacttgaaaaa	CRISPR spacer
tttcagactgagactgagccaaaactggacttgaaaaa	Protospacer
**************************************

101. spacer 5.13|152717|39|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aattccactatcgcaaaagttggagcaggactatcagtt	CRISPR spacer
aattccactatcgcaaaagttggagcaggactatcagtt	Protospacer
***************************************

102. spacer 5.14|152791|39|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tgttcgtacaccaactaaacgcgtcatggagccaagcaa	CRISPR spacer
tgttcgtacaccaactaaacgcgtcatggagccaagcaa	Protospacer
***************************************

103. spacer 5.15|152865|40|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

cgtgacctgttgccaggaatattaatgaaacagctaaaca	CRISPR spacer
cgtgacctgttgccaggaatattaatgaaacagctaaaca	Protospacer
****************************************

104. spacer 5.16|152940|37|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ctctttccagaactcttttatccttctcagtgggatt	CRISPR spacer
ctctttccagaactcttttatccttctcagtgggatt	Protospacer
*************************************

105. spacer 5.17|153012|36|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

gaaaaaacaagcgtaacatcgcctgaactataaaaa	CRISPR spacer
gaaaaaacaagcgtaacatcgcctgaactataaaaa	Protospacer
************************************

106. spacer 5.18|153083|39|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aggagggtacccttgctctttcaagattttttcatcaaa	CRISPR spacer
aggagggtacccttgctctttcaagattttttcatcaaa	Protospacer
***************************************

107. spacer 5.19|153157|39|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

cctcacgtgggctgtatcaacccaaataccagttgtaaa	CRISPR spacer
cctcacgtgggctgtatcaacccaaataccagttgtaaa	Protospacer
***************************************

108. spacer 5.20|153231|39|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttgccgccttgggaggtggagtttcctccgtttccacca	CRISPR spacer
ttgccgccttgggaggtggagtttcctccgtttccacca	Protospacer
***************************************

109. spacer 5.21|153305|41|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tcggtggcgttattctattcagtttctaaatcattttgcaa	CRISPR spacer
tcggtggcgttattctattcagtttctaaatcattttgcaa	Protospacer
*****************************************

110. spacer 5.22|153381|37|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttttcgtgcagaatcagcgagatcttttgaggcagaa	CRISPR spacer
ttttcgtgcagaatcagcgagatcttttgaggcagaa	Protospacer
*************************************

111. spacer 5.23|153453|37|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

atctgatttccggttgttatgcctaacataacaacta	CRISPR spacer
atctgatttccggttgttatgcctaacataacaacta	Protospacer
*************************************

112. spacer 5.24|153525|41|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

tcaaggcaattgcactcattgccgtagtcgaccaccaatac	CRISPR spacer
tcaaggcaattgcactcattgccgtagtcgaccaccaatac	Protospacer
*****************************************

113. spacer 5.25|153601|37|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

agcagatacaaacaaagatatcaatatataagctata	CRISPR spacer
agcagatacaaacaaagatatcaatatataagctata	Protospacer
*************************************

114. spacer 5.26|153673|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

cctctaagttggactgaaattttagctctctaaaa	CRISPR spacer
cctctaagttggactgaaattttagctctctaaaa	Protospacer
***********************************

115. spacer 5.27|153743|36|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ctcaagacacatattctttgcttttagtaaaacatt	CRISPR spacer
ctcaagacacatattctttgcttttagtaaaacatt	Protospacer
************************************

116. spacer 5.28|153814|36|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

attgtcgattgttccttggtcgcccttggcaaccaa	CRISPR spacer
attgtcgattgttccttggtcgcccttggcaaccaa	Protospacer
************************************

117. spacer 5.29|153885|43|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

ttttaatagaatacgaaactctaattataacaaatatcacaat	CRISPR spacer
ttttaatagaatacgaaactctaattataacaaatatcacaat	Protospacer
*******************************************

118. spacer 5.30|153963|36|NC_019772|CRISPRCasFinder,CRT matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

aacaaaatgttgaaagtgttgctttgtaattgaaat	CRISPR spacer
aacaaaatgttgaaagtgttgctttgtaattgaaat	Protospacer
************************************

119. spacer 3.20|59113|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to MG209611 (Aphanizomenon phage vB_AphaS-CL131, complete genome) position: , mismatch: 6, identity: 0.842

taatatctgggggattgagtgcgatcgccaaatagcag	CRISPR spacer
taatatttgggggattgagtgcgatcgcgcgatcgctg	Protospacer
******.*********************  .** ** *

120. spacer 2.4|31839|34|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043832 (Bacillus sp. BS98 plasmid unnamed2) position: , mismatch: 8, identity: 0.765

-ataatttagatccatttatttatcgttggaaatg	CRISPR spacer
cgtta-ccaaatccctttatttatcgttgaaaatg	Protospacer
 .* * ..*.**** **************.*****

121. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034093 (Acinetobacter baumannii strain A52 plasmid pA52-1, complete sequence) position: , mismatch: 8, identity: 0.789

gccaatt---tcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
---cattgagtctaaaagattgccaacaaatcattaaagaa	Protospacer
    ***   ** .***************** *** *****

122. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023025 (Acinetobacter baumannii strain 10324 plasmid pAba10324c, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

123. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041590 (Acinetobacter baumannii strain J9 plasmid pJ9-3, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

124. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039519 (Acinetobacter baumannii strain TG22653 plasmid pTG22653, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

125. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033864 (Acinetobacter sp. FDAARGOS_560 plasmid unnamed2) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

126. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010398 (Acinetobacter baumannii strain 6200 plasmid p6200-114.848kb, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

127. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015484 (Acinetobacter baumannii strain ORAB01 plasmid pORAB01-1, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

128. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018333 (Acinetobacter baumannii strain A1296 isolate A1296 plasmid pA1296_1, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

129. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to CP031744 (Acinetobacter baumannii WM99c plasmid pWM99c-2, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

130. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050905 (Acinetobacter baumannii strain DT-Ab057 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

131. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_020524 (Acinetobacter baumannii MDR-TJ plasmid pABTJ2, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

132. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021327 (Acinetobacter baumannii strain XH386 plasmid pXH386, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

133. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038645 (Acinetobacter baumannii strain ACN21 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

134. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to CP033517 (Acinetobacter baumannii strain 2008S11-069 plasmid p2008S11-069-1, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

135. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016301 (Acinetobacter baumannii strain CMC-CR-MDR-Ab66 plasmid pCMCVTAb1-Ab66, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

136. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016296 (Acinetobacter baumannii strain CMC-CR-MDR-Ab4 plasmid pCMCVTAb1-Ab4, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

137. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016299 (Acinetobacter baumannii strain CMC-MDR-Ab59 plasmid pCMCVTAb1-Ab59, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

138. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024125 (Acinetobacter baumannii strain AYP-A2 plasmid pAYP-A2, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

139. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026128 (Acinetobacter baumannii strain ABNIH28 plasmid pABA-1fe1, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

140. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020585 (Acinetobacter baumannii strain CBA7 plasmid pCBA7_1, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

141. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_023031 (Acinetobacter baumannii ZW85-1 plasmid ZW85p2, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

142. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MK386680 (Acinetobacter baumannii strain ABAY04001 plasmid pABAY04001_1A, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

143. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018257 (Acinetobacter baumannii strain AF-673 plasmid pAF-673, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

144. spacer 3.28|59712|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010780 (Acinetobacter baumannii strain XH386 plasmid pAB386, complete sequence) position: , mismatch: 9, identity: 0.763

-gccaatttcagaaagattgccaacaaatgatttaagaa	CRISPR spacer
cattaagtcta-aaagattgccaacaaatcattaaagaa	Protospacer
 ...** *..* ***************** *** *****

145. spacer 3.47|61108|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to MN694447 (Marine virus AFVG_250M387, complete genome) position: , mismatch: 10, identity: 0.714

aatccaattaagaacagaaataaataactcatctt	CRISPR spacer
gacacaattaaaaagagaaataaataactttatta	Protospacer
.*. *******.** **************.  .*

146. spacer 3.47|61108|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to MN694065 (Marine virus AFVG_250M443, complete genome) position: , mismatch: 10, identity: 0.714

aatccaattaagaacagaaataaataactcatctt	CRISPR spacer
gacacaattaaaaagagaaataaataactttatta	Protospacer
.*. *******.** **************.  .*

147. spacer 2.4|31839|34|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to MN693811 (Marine virus AFVG_250M463, complete genome) position: , mismatch: 11, identity: 0.676

ataatttagatccatttatttatcgttggaaatg	CRISPR spacer
gtaatttagatccttttatttttcgagcagcact	Protospacer
.************ ******* ***   .. *.

148. spacer 3.24|59415|38|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_019544 (Deep-sea thermophilic phage D6E, complete genome) position: , mismatch: 11, identity: 0.711

gagaaaatgacagaagaacaagcaaaagaacttttaat	CRISPR spacer
gcaaaaataacagaggaacaagcaaaagaaataaagtc	Protospacer
* .*****.*****.*************** *   . .

149. spacer 3.29|59787|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897276 (Clostridium botulinum strain INGR16-02E1 plasmid pINGR16-02E1, complete sequence) position: , mismatch: 11, identity: 0.686

ttaaaatcagccatgatctttaataattaaattta	CRISPR spacer
cttgttatagccataatctttaattattaaattat	Protospacer
.* .   .******.********* ********

150. spacer 3.29|59787|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897280 (Clostridium botulinum strain FI1111E1 plasmid pFI1111E1, complete sequence) position: , mismatch: 11, identity: 0.686

ttaaaatcagccatgatctttaataattaaattta	CRISPR spacer
cttgttatagccataatctttaattattaaattat	Protospacer
.* .   .******.********* ********

151. spacer 3.29|59787|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897275 (Clostridium botulinum strain IFR 12/29 plasmid p12/29, complete sequence) position: , mismatch: 11, identity: 0.686

ttaaaatcagccatgatctttaataattaaattta	CRISPR spacer
cttgttatagccataatctttaattattaaattat	Protospacer
.* .   .******.********* ********

152. spacer 3.29|59787|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897277 (Clostridium botulinum strain ST0210E1 plasmid pST0210E1, complete sequence) position: , mismatch: 11, identity: 0.686

ttaaaatcagccatgatctttaataattaaattta	CRISPR spacer
cttgttatagccataatctttaattattaaattat	Protospacer
.* .   .******.********* ********

153. spacer 3.29|59787|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897278 (Clostridium botulinum strain FWSKR40E1 plasmid pFWSKR40E1, complete sequence) position: , mismatch: 11, identity: 0.686

ttaaaatcagccatgatctttaataattaaattta	CRISPR spacer
cttgttatagccataatctttaattattaaattat	Protospacer
.* .   .******.********* ********

154. spacer 3.29|59787|35|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897279 (Clostridium botulinum strain SWKR38E2 plasmid pSWKR38E2, complete sequence) position: , mismatch: 11, identity: 0.686

ttaaaatcagccatgatctttaataattaaattta	CRISPR spacer
cttgttatagccataatctttaattattaaattat	Protospacer
.* .   .******.********* ********

155. spacer 5.2|151926|39|NC_019772|PILER-CR,CRISPRCasFinder,CRT matches to NC_017064 (Helicobacter pylori ELS37 plasmid pHPELS37, complete sequence) position: , mismatch: 11, identity: 0.718

gttttctgttttgaatctaaaaaagaaatgattttctct	CRISPR spacer
tgctgttgtttgtaatctaaaaaagaaatgatttgatag	Protospacer
  .* .*****  *********************  *

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage