CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_019770	Enterococcus faecalis str. Symbioflor 1, complete genome	3 crisprs	csa3,cas3,cas14j,DinG,DEDDh	0	11	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_019770_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019770_1

1760747-1761376

Orphan

II-A,II-B

Consensus_repeat	Method
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRISPRCasFinder
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRT
TGTTTTGGCACCATTCTAAACAACATGACTCTAAAACCAATTGAT	PILER-CR
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	PILER-CR

9 spacers

The CRISPR arrays of NC_019770_1

>merge|NC_019770|1|1760747-1761376|CRISPRCasFinder,CRT,PILER-CR,PILER-CR
GTGATAGTTTGTTTTTAAACAACATGACTATAAAACAGGGGAGAAAAAGCCAAATCAAAAAAGTTTGTTTTGGTACCATTCTAAACAACATGACTCTAAAACGAATTGATAATTGAAGCCTTAACAAGTAATGTTTTGGCACCATTCTAAACAACATGACTCTAAAACCTTTTGATTTTGGTGCTAATGCATCAAAATGTTTTGGTACCATTCTAAACAACATGACTCTAAAACATGAACTAAATGTTTCAGATTCTCAAATAAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACTCTGGTAAATTCTTAATGTCTGCATAGGTAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACTAGCCTAAAATTAATACATCATTTTCGATAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACATACCATCCGCAGTTGGTGTAAGTTCGGTTGTTTTGGTACCATTCTAAACAACATGACTCTAAAACATGACTATGCGAAAGTTAATCGTTTGTTACGTTTTGGTACCATTCTAAACAACATGACTCTAAAACAGAAAGTGGGGAATGCGTAATGCCGTACTTGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NC_019770|1|1|1760747-1761376|CRISPRCasFinder
GTGATAGTTTGTTTTTAAACAACATGACTATAAAAC	AGGGGAGAAAAAGCCAAATCAAAAAAGTTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GAATTGATAATTGAAGCCTTAACAAGTAAT
GTTTTGGCACCATTCTAAACAACATGACTCTAAAAC	CTTTTGATTTTGGTGCTAATGCATCAAAAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ATGAACTAAATGTTTCAGATTCTCAAATAA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TCTGGTAAATTCTTAATGTCTGCATAGGTA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TAGCCTAAAATTAATACATCATTTTCGATA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ATACCATCCGCAGTTGGTGTAAGTTCGGTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ATGACTATGCGAAAGTTAATCGTTTGTTAC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AGAAAGTGGGGAATGCGTAATGCCGTACTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NC_019770|1|1|1760747-1761376|CRT
GTGATAGTTTGTTTTTAAACAACATGACTATAAAAC	AGGGGAGAAAAAGCCAAATCAAAAAAGTTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GAATTGATAATTGAAGCCTTAACAAGTAAT
GTTTTGGCACCATTCTAAACAACATGACTCTAAAAC	CTTTTGATTTTGGTGCTAATGCATCAAAAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ATGAACTAAATGTTTCAGATTCTCAAATAA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TCTGGTAAATTCTTAATGTCTGCATAGGTA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TAGCCTAAAATTAATACATCATTTTCGATA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ATACCATCCGCAGTTGGTGTAAGTTCGGTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ATGACTATGCGAAAGTTAATCGTTTGTTAC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AGAAAGTGGGGAATGCGTAATGCCGTACTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NC_019770|1|1|1760759-1760923|PILER-CR
TTTTAAACAACATGACTATAAAACAGGGGAGAAAAAGCCAAATCAAAAAAG	TTTGTTTTGGTACCATTCTAAACA
ACATGACTCTAAAACGAATTGATAATTGAAGCCTTAACAAGTAATGTTTTG	GCACCATTCTAAACAACATGA
CTCTAAAACCTTTTGATTTTGGTGCTAATGCATCAAAATGTTTTGGTACCATTCTAAACAACATGACTCTAAAACATGAACTAAATGTTTCAGATTCTCAAATAAGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TCTGGTAAATTCTTAATGTCTGCATAGGTA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TAGCCTAAAATTAATACATCATTTTCGATA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ATACCATCCGCAGTTGGTGTAAGTTCGGTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ATGACTATGCGAAAGTTAATCGTTTGTTAC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AGAAAGTGGGGAATGCGTAATGCCGTACTT


>NC_019770|1|2|1761011-1761376|PILER-CR
	TTTGTTTTGGTACCATTCTAAACA
ACATGACTCTAAAACGAATTGATAATTGAAGCCTTAACAAGTAATGTTTTG	GCACCATTCTAAACAACATGA
CTCTAAAACCTTTTGATTTTGGTGCTAATGCATCAAAATGTTTTGGTACCATTCTAAACAACATGACTCTAAAACATGAACTAAATGTTTCAGATTCTCAAATAAGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TCTGGTAAATTCTTAATGTCTGCATAGGTA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TAGCCTAAAATTAATACATCATTTTCGATA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ATACCATCCGCAGTTGGTGTAAGTTCGGTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ATGACTATGCGAAAGTTAATCGTTTGTTAC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AGAAAGTGGGGAATGCGTAATGCCGTACTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019770.1\|WP_002364369.1\|1756173_1757907_-\|thiol-reductant-ABC-exporter-subunit-CydD	unknown	unknown	gnl\|CDD\|274323
NC_019770.1\|WP_002356974.1\|1758921_1760340_-\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NC_019770.1\|WP_002366913.1\|1769572_1770718_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NC_019770.1\|WP_002360016.1\|1752323_1753229_-\|prenyltransferase	unknown	unknown	gnl\|CDD\|235695
NC_019770.1\|WP_002381711.1\|1746647_1747397_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NC_019770.1\|WP_002356959.1\|1769160_1769505_-\|DUF1831-domain-containing-protein	unknown	unknown	gnl\|CDD\|370163
NC_019770.1\|WP_002360015.1\|1753350_1754331_+\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|223220
NC_019770.1\|WP_002369152.1\|1766391_1767624_+\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NC_019770.1\|WP_002356966.1\|1764694_1765060_-\|DUF1033-family-protein	unknown	unknown	gnl\|CDD\|336361
NC_019770.1\|WP_002411395.1\|1754410_1756177_-\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320
NC_019770.1\|WP_002356976.1\|1757911_1758925_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|376764
NC_019770.1\|WP_002362073.1\|1765859_1766375_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|176643
NC_019770.1\|WP_002356960.1\|1767810_1768935_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
NC_019770.1\|WP_010816137.1\|1770874_1771849_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|235039
NC_019770.1\|WP_002411391.1\|1748346_1750770_-\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|224588
NC_019770.1\|WP_002411399.1\|1765157_1765727_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115
NC_019770.1\|WP_002356983.1\|1747514_1748216_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NC_019770.1\|WP_002383730.1\|1762482_1764732_-\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
NC_019770.1\|WP_002411398.1\|1761534_1762398_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NC_019770.1\|WP_002411392.1\|1751083_1752295_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172

Protein	Function_ID	Function_description	E-value
NC_019770.1\|WP_002364369.1\|1756173_1757907_-\|thiol-reductant-ABC-exporter-subunit-CydD	gnl\|CDD\|274323	TIGR02857, transport_ATP-binding_protein, thiol reductant ABC exporter, CydD subunit. The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD.	0
NC_019770.1\|WP_002356974.1\|1758921_1760340_-\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	0
NC_019770.1\|WP_002366913.1\|1769572_1770718_-\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	3.38321e-179
NC_019770.1\|WP_002360016.1\|1752323_1753229_-\|prenyltransferase	gnl\|CDD\|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	8.82053e-105
NC_019770.1\|WP_002381711.1\|1746647_1747397_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	2.63593e-110
NC_019770.1\|WP_002356959.1\|1769160_1769505_-\|DUF1831-domain-containing-protein	gnl\|CDD\|370163	pfam08866, DUF1831, Putative amino acid metabolism. Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.	1.33245e-53
NC_019770.1\|WP_002360015.1\|1753350_1754331_+\|polyprenyl-synthetase-family-protein	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	2.52576e-80
NC_019770.1\|WP_002369152.1\|1766391_1767624_+\|multidrug-efflux-MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.02154e-172
NC_019770.1\|WP_002356966.1\|1764694_1765060_-\|DUF1033-family-protein	gnl\|CDD\|336361	pfam06279, DUF1033, Protein of unknown function (DUF1033). This family consists of several hypothetical bacterial proteins. Many of the sequences in this family are annotated as putative DNA binding proteins but the function of this family is unknown.	4.62165e-64
NC_019770.1\|WP_002411395.1\|1754410_1756177_-\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	0
NC_019770.1\|WP_002356976.1\|1757911_1758925_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|376764	pfam02322, Cyt_bd_oxida_II, Cytochrome bd terminal oxidase subunit II. This family consists of cytochrome bd type terminal oxidases that catalyze quinol-dependent, Na+-independent oxygen uptake. Members of this family are integral membrane proteins and contain a protohaem IX centre B558. One member of the family, Klebsiella pneumoniae CydB, is implicated in having an important role in micro-aerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae. The family forms an integral functional unit with subunit I, family Bac_Ubq_Cox, pfam01654.	9.60464e-103
NC_019770.1\|WP_002362073.1\|1765859_1766375_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|176643	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea. PhosphatidylEthanolamine-Binding Proteins (PEBPs) are represented in all three major phylogenetic divisions (eukaryotes, bacteria, archaea). The members in this subgroup are present in bacterial and archaea. Members here include Escherichia coli YBHB and YBCL which are thought to regulate protein phosphorylation as well as Sulfolobus solfataricus SsCEI which inhibits serine proteases alpha-chymotrypsin and elastase. Although their overall structures are similar, the members of the PEBP family have very different substrates and oligomerization states (monomer/dimer/tetramer). In a few of the bacterial members present here the dimerization interface is proposed to form the ligand binding site, unlike in other PEBP members.	1.1162e-31
NC_019770.1\|WP_002356960.1\|1767810_1768935_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NC_019770.1\|WP_010816137.1\|1770874_1771849_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|235039	PRK02458, PRK02458, ribose-phosphate pyrophosphokinase; Provisional.	0
NC_019770.1\|WP_002411391.1\|1748346_1750770_-\|DNA-translocase-FtsK	gnl\|CDD\|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	7.74237e-175
NC_019770.1\|WP_002411399.1\|1765157_1765727_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	4.37526e-15
NC_019770.1\|WP_002356983.1\|1747514_1748216_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	5.36718e-38
NC_019770.1\|WP_002383730.1\|1762482_1764732_-\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NC_019770.1\|WP_002411398.1\|1761534_1762398_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.88908e-26
NC_019770.1\|WP_002411392.1\|1751083_1752295_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	1.22837e-121

>NC_019770.1|WP_002356974.1|1758921_1760340_-|cytochrome-ubiquinol-oxidase-subunit-I
MFDIVTLARIQFAMTTVFHFFFVPFSIGLALVVAIMETMYVVKKEERYRKMAKFWGNIFLLSFAVGVVTGIIQEFQFGMNWSDYSRFVGDIFGAPLAVEALLAFFLESTFLGLWIFTWDKMNPKVHVTFIWLVVFGSMMSAFWILVANSFMQHPVGYVINNGRAEMVDFVAVISNPKVWYEFSHVIMGAFTLGGMAVAGMAAFQLLKKRDISFHKASMRIGLWVTLFGSIGVLLAGDLQMKALIEGQPMKFAAMEGAYEDSDDPAAWTLIAWADEREHKQVFGIDIPYMLSILSYNKLSGSVDGMDTVNKRLVEKYGDDKNYYPPVNTLFWSFRIMAGFGALMLLVAALGLFFTRKKKPSLYEKKWMLWIVALCTFAPFLANTTGWLVTELGRYPWTVYGLFTIEQSVSPNVSVASLITSNVIYFLLFAGLGSVMVYLVILELRKGPDYEAKKLAKENEPALDPFDKGVFGE
>NC_019770.1|WP_002356976.1|1757911_1758925_-|cytochrome-d-ubiquinol-oxidase-subunit-II
MSTLQLLWFVLIGVLFSGFFFLEGFDFGVGMAVQTLAHNDDEKDQVVATIGPVWDGNEVWLLTAGGAMFASFPYWYASLFSGYYLILFTILFGLIIRGVSFEFRHNMPEGKRRRMWNWTLSIGSFLVPFFFGILFISLVQGMPLDANGNMHAQFTDYFNLFSIVGGVALTLLCYLHGMNYIALKTEGPIRERARNYAEILYGVLYVGLVVFAVLMYFKTDFYEKNFAVTLILTLAIVVLTVIANVGVFKRKEMLAFLASGLTLVVLVALLFSGLFPRVMIGSEGFDLLIKDATSTPYTLKIMTWISLSILPFVLAYTAWSYYIFRKRISQTAVPEGY
>NC_019770.1|WP_002364369.1|1756173_1757907_-|thiol-reductant-ABC-exporter-subunit-CydD
MIDKDILQMPKIKKILVLLAGFSFLQAVFIIGQAFFLSKAIVGLWSGGHLNQQLQSILLFFIFYLGRHVITYFRERMLDTFSYERSKELREQLLTKIFRLGPNVVQKNGTGNMVTMALEGISQTENYLQLILTKMMNMMIIPWIILAFVFTQDIRSGVTLLIVFPIIIIFMIVLGYAAQSKADKQYAAFQMLSNHFIDSLRGIDTLKLFGLSKKYAGSIYHTSERFRKATMSTLKIAILSTFALDFFTTLSVAVVAVFLGLSLLNGTILLFPALVTLILAPEFFLPIRDFSSDYHATLDGKNSFQAIQAVLALPEAEQTDVLTLDDWHQESQLSVTALNFSYEDATQEAIQSLQFSVDGRKKIGIIGASGSGKSTLINLLSGFLLPTEETSQLAINGQTIPHFLQKDWQKQILYIPQAPYIFQDTLANNIRFYTPEATDEAIQQAIQLVGLDELVKDLPEGIHTLIGESGRMLSGGQAQRVALARAFVDQKRHVLLFDEPTAHLDIETEVEMKERMLPLMNNHLVFFATHRLHWMEEMDYILVMEKGQLVEQGTLAELIEKDGYYVQLMKQMRGGRQ
>NC_019770.1|WP_002411395.1|1754410_1756177_-|thiol-reductant-ABC-exporter-subunit-CydC
MMEKQPTTKDVWKNDQWVRPFLKRYKKTLYFALLLGFLTFFSAGALMFTSGYLISRAASLPENILLIYIPIVLTRAFGIGRPVFRYVERLTSHNWVLKMTSDLRLKLYNVLEKDAIFFKTKYRTGDILGLLSEDINHIQNLYLRTIFPTVIAWILYIFLVIALGFFSWWFALCMLLMLGVVVFLLPLVSVLVNGARQEKHKYAKNELYQTLTDNILGVSDWVFSQRGAEFVARYETDEANVRALDEKMKQFNRGRDFVLQLLFGVIAIAVLAWTSVRFPGNHGGAANWIGAFVLTVFPLIDAFAPLPAAAQETTIYKDSIRRFNELPEGEDDSTEAPVQPNGTSLSIEHLSFAYENQEKKVLNDLSLTIPEKQKLAILGRSGSGKSTLASLIRGDLRPTSGEILLGNIPTEAFGETMTEYIGVMHQAPYLFRTTILNNIRIGREEASEAEVWAVLEKVGLKEMVAQLPEGLQTMVDEAGLRFSGGERHRLALARILLQDTPIVLLDEPTTGLDPITEQQLLETFFEALKDKTVIWITHHLQGVTLMDQVIFIEDGQLEMSGTPEELLATNAHYQKLYRIDRGISSFEE
>NC_019770.1|WP_002360015.1|1753350_1754331_+|polyprenyl-synthetase-family-protein
MNTFWKSFPDVERSLTETCELIEQTLHTRNEDIEEALVTLARSGGKLLRPAFFFLFAQLGDEEKQEKQQLLKIAASLEILHMATLIHDDIIDDSPLRRGAVTIQSQYGKDVAVYTGDLLFTEFFTLIADAMNGSEFMKINAQGMKRLLLGELDQMSHRFDRRMSIPAYLRSVNGKTAELFSLSCLEGAYFGHSSKEVQRLAKRIGRHIGIAFQVYDDILDYTADTETLKKPALEDLSQGVYTLPLLFAYQAAPDVFSPYLDKGRAITLEEAAEVAALVNDYHGVTEAQAFAKKVTNKAITDIQQLPDGTAKETLLSLTELLLHRSF
>NC_019770.1|WP_002360016.1|1752323_1753229_-|prenyltransferase
MNREIFFELVELKAKTASVLPFLLGICFSWYQYGRLHVGYVLIFFIAMFIFNMAVDILDNYNDYHHATEVHDYKEKTNIIGRENLSLPLIRKMIFWMILVSALMGIGLSFIVGWPLLIMGLYCYLIGIFYSSGPKPLSSLPLGEVFSGFTMGFMITLICVYINTFEVFNWSAANLWGIFLVALPNTCYIANLMLANNICDLEEDENNKRYTLVHYLGKASSLKLFVGLNTIAMLAILLAVGLGLTPPTMLLMLLTLPFVRKQTQALLKEQVKSKTFVCAVKILAVGATAQVLFFAIGLWWL
>NC_019770.1|WP_002411392.1|1751083_1752295_-|NAD(P)/FAD-dependent-oxidoreductase
MNKKHVVILGAGYAGLKTLRELQKGAKDVEITLVDRNNYHYEATDLHEVAAGTQPAEKITYNIMDVVDEKMTTFIQGTVKTIDAATQTVALEDGQTINYDYLVVSLGFESESFGIPGVQEHALQMVDVKTALNVYEHIQEQMRQYKATQNEEFLKIVVCGAGFTGIELLGSLVENKPKFAEIAGVSADQIQIYCVEAVTRLLPMFNEKLANYGVQLLKDSAIHLLLGKPIKEIKPSAVVYQDNEAGDLAELSAKTIIWTTGVSGSHVVGDSGFEARRGRVMVQPDLTDANHSNVYIIGDCSAVMDTETNRPYPTTAQIALKMGAHAAKNIQAQLKGEATKPFSFKSQGSVCSVGNTRALGIVGKTDIKGYPASFMKKIIMNKALFETGGTKEMMAKGRFDLYH
>NC_019770.1|WP_002411391.1|1748346_1750770_-|DNA-translocase-FtsK
MAQKRATNKKKSTTKKKTKKQQQQQERLNYMFLGLIFILFGVFGLFRLGFLGTLLANCLRLVVGNTFPFAAILLILYGLLVMIYGKDFPLKRGRPIFGAVLIYISVLLFFHAFMFRNVSGSQPDILGNTWEFLQSDLKANQVTQNVGGGMIGALLYQGTYFLVAQFGSYLIATLLLLAGIFLMSMWDFQQIVDHFQSIQDRLSHVSAKSQARQEEKEAKRAAKKEAKAAERQAKIEAAAQQKLQKRERMEQAAAERLTKTPVETHQPMMEEPAAPTPVQIDSFQQQNQAMPVPPIAATKPQREQEEEAADEAGVLEFEISEEAEDRDYQLPPTDLLDTIQATDQSGEYEKIEKNIGVLEQTFKSFGVDAKVVKASLGPSVTKFEVQPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNSAISTVSFRDIVEAQPSHPDKLLEVPLGRDISGMVQTADLSKMPHLLIAGSTGSGKSVAINGIITGILMQAKPHEVKLMMIDPKMVELNVYNGIPHLLTPVVTNPRKAAQALQKVVQEMEFRYEKFAATGVRNITGYNQLIQQKNAEDGENRPILPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDTNGAEKLLGRGDMLFLPMGENKPIRIQGAFISDQEVERVVAFVTDQQEAEYQESMMPTDEPTTSGGGEAPQDELFEEAKNLVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVIGPSEGSKPRKVFLQAESEEAAPETPEQ
>NC_019770.1|WP_002356983.1|1747514_1748216_-|GntR-family-transcriptional-regulator
MRRKSVLYLEVADQIKEDILSGKYPVGTFLPTETELEEMFNVSKITIRRAIEMLATEEFVEKKSGRGTTVLSNRPYNKLSKAGTFTEFLNESGQKVTKKVLQVENLTLSKEMPAYQFLGEEVVHLSRLYLIDEQPYIYFNYYLPAAMKDVSLTEYKEESLYRLMDRHAIEIYKFEDRFEVATLTEAEQKMLQTTETTGLKRIRRSLSPTGRCVEYSEAIYNTKIHPYVIEYEA
>NC_019770.1|WP_002381711.1|1746647_1747397_-|ABC-transporter-ATP-binding-protein
MLEVQNLKKVYGNEIKYEALKGINLTVQDGEFIGIMGPSGSGKSTLLNLLATIDSPTDGEILLNGKNPNNLNQEQIAKFRRTELGFVFQSFNLMPTLTVEENIILPLTLDGEKVSVMKRQLAELSERLGINHLLKKRIAEISGGQAQRVAVARAMIHHPQLLLADEPTGNLDTKSSKDVMGLLQQLNEEEAATILMVTHDPLAASYCKRIVFIKDGELIDEIVQNGNQKEFYDLIMVKLAEIEGVDNEF
>NC_019770.1|WP_002411398.1|1761534_1762398_-|AraC-family-transcriptional-regulator
MLANLNQAIDYIEEHLTEEVSFDELAKKTGISVYHFKRTFSFIAGMSLAEYIKKRRLAEANLALLAGEKVTDVAFKYGYQSIEGFSRAFRDWSGQAPSEVMKTQIQKTFPKFSFYIDIKGGQSMDVKLIEKPAFQIVGVSQKVPLQYQGENQAIMELAQRITPQQRAEMHTFDDIYPHQVVNASFDFQEGRTTEGGEMTHMIGFATSQENTYEDLEQLSVPAHTWAVFPNEGPFPQTLQETWARIFSEWLPSSGYQVVAAPEISFTQYQGPAEAKYSEIWLAVTATK
>NC_019770.1|WP_002383730.1|1762482_1764732_-|DNA-topoisomerase-III
MAKQNSANGKLFETHEFKEKPQGIFFKLFFYSRNLEKIEPIFGIIRKDSTQKGAKLVVAKQLIIAEKPSVAKDLSRVLGANQKNKNYYEGPNVIVTWALGHLLGLKMPEDLNKEWQTWQMETLPMIPKNLGIKPLPKTGHQLKAIKQLANRKDVSEAVIATDAGREGELVARWILEYVRFNKPVKRLWISSQTDKAIKDGFKKIRPAKDYDNLYYSALARAKADWLVGLNVTRALTVKYQDNLSAGRVQTPTLAMVRQQEKTIEQFKPQTYFTISLSVESEKAKMTQKNPYALKERQEAEQLVKELSKQKGLVTDIQEKVKTENAPLPYDLTEIQREANQRFQFSAKKTLSLVQSLYETHKIVSYPRTDSKYLTTDMKGTMKERLQAIADFSPEVKGYLKNGAVVKQQKVFQNAKVTDHHGLIPTEQRPRYEKLSNDEQKIYQMIVQRFLGLFAEPNQTKQTKVTVAFGKETFVFHQNKVVVAGWKTTAEQPLSTVQWQKGMTVAPNFTINKELTSPPKPLTEGTLLGKMEKHSLGTPATRAEIIEKLIKSELMERTNSGLSVSAKGKQLLDLVNPSLVTPELTEKWEKSLEAIASGQQKSQLFLKDIEEDTKKLVREIKQSEKKYQDFSITQKKCPDCGSNLREKNTKDGKIYVCTNQECSYRRRKDPKVSNHRCPQCHKKMVIIEGKNGRSFKCKFCSITEKIPDKKERKQKMTKHEERRLMKKYSQPDEPEESALAQALKAAMNQE
>NC_019770.1|WP_002356966.1|1764694_1765060_-|DUF1033-family-protein
MYQVITMYGDNEPWWFFDDWQEDIVQEKTFDNLTDAETYYVEVWQKLSQNYTYVNTKPNYLTAFWNDGEERWCEECDEDLQQYFGLALLENHHAVTFENKAEFTTISNHFGKTKFCKRKVI
>NC_019770.1|WP_002411399.1|1765157_1765727_-|TetR/AcrR-family-transcriptional-regulator
MAKKRNLTKAKILESARNLAEELGVHQLTFQNLAVDLGIKYPSLYNHFKNIAEVKNALVDLLIQELNDALRRALVGKSGAEAIRIYAETYQQFAFENSAVYELLISVPKTQNQQLIEGIHETNQIILQLLAFYPFNNEERLHKSRELRSLIHGYITLRFLGYFQREEATPEESYRRMIEDFIASLEVAG
>NC_019770.1|WP_002362073.1|1765859_1766375_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MHITNRSHLADRYGKRTSAEFLLHERPILSFPISLAAIPKEARYLSWELIDYDTIPLIGFPFIHWLAANVPVTNEIPEDFSRTALKPTIQGKNSLASPLGKQMIPALATETLPELTERYLGLSPRSGVHTYTLYVYATKNPLNLKEGFFANELHQALNDQRLAKAKFEFLY
>NC_019770.1|WP_002369152.1|1766391_1767624_+|multidrug-efflux-MFS-transporter
MYELIKSKIFRPRQPWEKNLLVLWFGTFMAGIGFSLVMPFMPLYINTLGTFTHQQLNFWSGITFSSTFLVTTIVSPWWGRLADRKGRKLMLLRASLGMAIVISLMGAVTSVYQLIGLRLLQGVFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTLLGPLLGGVTASIFGYRPTFFITGTILLLVFVLSLVFVHEEFVPIEKNQAASGKQILKKLEHPHVILGMFITTLIIQASNNSISPIISLYIQQLLGGHGNVTLISGVIASIPGIATLIAAPRFGRLGDRIGSERILTIGLILAIFVYLPMAFVQNVWQLAMLRFLVGISDACLLPAVQTLITRYSPSDAAGRIFSYNQSFQATGNVIGPMIGSSVSAAFGYRGVFISTSCLVLLNLLWVRRSTAELKKREK
>NC_019770.1|WP_002356960.1|1767810_1768935_-|tRNA-2-thiouridine(34)-synthase-MnmA
MADNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVAKVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRLGRTPNPDVMCNKEIKFKAFLDYAMQLGADYVATGHYAQVETDENGVVHMLRGIDNNKDQTYFLSQLSQAQLAKTMFPLGGMEKSEVRAIADRAGLATAKKKDSTGVCFIGEKNFKEFLSNYLPAKKGNMVTEDGEIKGQHDGLMYYTIGQRQGLGIGGGGKTQEPWFVIGKDLTTNTLYVGQGFHHEKLYATHLEASEVHFTVDTPMPKEFDCTAKFRYRQADIPVHVSLSEDGTKATVTFKEPARAVTPGQAVVFYDGMECLGGGLIDRAYQDEKELQYV
>NC_019770.1|WP_002356959.1|1769160_1769505_-|DUF1831-domain-containing-protein
MAFTTTAAVEGSTVFYKVHPSAKRYTLKDNGFTETKSGNFQLIRSLDPTPQRNEGFKLKITITADLKELKMSITTANGLKPMNIFKNEQHEMSKEKYFFLMDGLISRGVLEKVE
>NC_019770.1|WP_002366913.1|1769572_1770718_-|cysteine-desulfurase
MEPIYLDHAATTPLHPTVIQAMTENMQTTFGNPSSIHQFGRKAHGLLEEVRQTIAESLQAKPHEIIFNSGGTEGDNTAILAVAFSRQKEGKHIITTAIEHPAVLRTMEYLETLGFEVTYLPVNENGQISMDQFKKSLREETILVSMMYGNNEIGNRLPIAEVGAILKNHSAIFHTDAVQAYGSEVILPHELGIDLLSISAHKINGPKGVGFLFKSDAIQLPPLLHGGEQEEKRRAGTENLAGIIGMGTAVSLLTSTEKQARKTAYQSFQTIILKALEEANIDFSINGEPTNRLAHVLNLHLKGIPSDLLLMHLDLRGIAISTGSACTAGTVDPSHVLTAMYGENSSAIKESIRISFGYGNTPEEIATFSEVLVAVIQQLKK
>NC_019770.1|WP_010816137.1|1770874_1771849_-|ribose-phosphate-diphosphokinase
MTENYQDDTLRIFSLNANRPLAEKIAASVGTELGKSTVRQFSDGEIQINIEESIRGDHVYIIQATNAPVNDHLMELLILIDALKRASAKTINVILPYYGYARQDRTAKPREPITAKLVANMLVEAGATRLLTLDLHTVQVQGFFDIPVDNLFTMPLFAHYYRQQALVGEEIVIVSPKNSGVQRARSLSEYLDATLAIVDHEEIDGVRQEGYVIGNVAGKKCILVDDILNTGQTLATAAEVLMKNGAQEVYACTSHGLLSEGAKATLENAPIKEISITDSVYTTADRQPATLNIISCAELMGEALLRIHENKPMSPLFRLEPKGE

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Crispr_ID: NC_019770_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019770_2

1972412-1972524

Orphan

Consensus_repeat	Method
CTCCATGTTTTTGGCTAAACAGTTTGTTTTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019770_2

>merge|NC_019770|2|1972412-1972524|CRISPRCasFinder
CTCCATGTTTTTGGCTAAACAGTTTGTTTTAGCACAGAGGAGACAACGTTCCCTTTGGTCACCTTGTACTGTTCATCATCTACTCCATGTTTTTGGCTAAGCAGTTTGTTTTA

>NC_019770|2|2|1972412-1972524|CRISPRCasFinder
CTCCATGTTTTTGGCTAAACAGTTTGTTTTA	GCACAGAGGAGACAACGTTCCCTTTGGTCACCTTGTACTGTTCATCATCTA
CTCCATGTTTTTGGCTAAGCAGTTTGTTTTA

Protein	Signature genes	Signature genes Name	Protein_function
NC_019770.1\|WP_002379669.1\|1971367_1972276_-\|glycine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|236473
NC_019770.1\|WP_002411113.1\|1968084_1969017_+\|membrane-protein-insertase-YidC	unknown	unknown	gnl\|CDD\|235040
NC_019770.1\|WP_002382766.1\|1969050_1969242_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181104
NC_019770.1\|WP_002356757.1\|1966759_1967536_-\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|223640
NC_019770.1\|WP_002356741.1\|1979047_1979497_-\|GatB/YqeY-domain-containing-protein	unknown	unknown	gnl\|CDD\|370480
NC_019770.1\|WP_002387080.1\|1979864_1980305_-\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|133478
NC_019770.1\|WP_002382764.1\|1974799_1975201_-\|diacylglycerol-kinase-family-protein	unknown	unknown	gnl\|CDD\|260134
NC_019770.1\|WP_002356745.1\|1975184_1975664_-\|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl\|CDD\|234575
NC_019770.1\|WP_002389973.1\|1980403_1981261_+\|kinase/pyrophosphorylase	unknown	unknown	gnl\|CDD\|377080
NC_019770.1\|WP_002382765.1\|1973006_1973801_-\|DNA-repair-protein-RecO	unknown	unknown	gnl\|CDD\|273175
NC_019770.1\|WP_002356759.1\|1965333_1966119_-\|30S-ribosomal-protein-S2	unknown	unknown	gnl\|CDD\|235396
NC_019770.1\|WP_002356740.1\|1979522_1979699_-\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
NC_019770.1\|WP_015212220.1\|1975663_1977862_-\|HDIG-domain-containing-protein	unknown	unknown	gnl\|CDD\|224397
NC_019770.1\|WP_002356760.1\|1964346_1965228_-\|elongation-factor-Ts	unknown	unknown	gnl\|CDD\|236491
NC_019770.1\|WP_002411111.1\|1969281_1971366_-\|glycine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234925
NC_019770.1\|WP_002356761.1\|1963363_1964086_-\|UMP-kinase	unknown	unknown	gnl\|CDD\|239787
NC_019770.1\|WP_002382772.1\|1966302_1966740_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|236715
NC_019770.1\|WP_002356743.1\|1977890_1978913_-\|PhoH-family-protein	unknown	unknown	gnl\|CDD\|224616
NC_019770.1\|WP_010706543.1\|1967642_1967918_+\|acylphosphatase	unknown	unknown	gnl\|CDD\|224174
NC_019770.1\|WP_002359745.1\|1973883_1974786_-\|GTPase-Era	unknown	unknown	gnl\|CDD\|234624

Protein	Function_ID	Function_description	E-value
NC_019770.1\|WP_002379669.1\|1971367_1972276_-\|glycine--tRNA-ligase-subunit-alpha	gnl\|CDD\|236473	PRK09348, glyQ, glycyl-tRNA synthetase subunit alpha; Validated.	0
NC_019770.1\|WP_002411113.1\|1968084_1969017_+\|membrane-protein-insertase-YidC	gnl\|CDD\|235040	PRK02463, PRK02463, OxaA-like protein precursor; Provisional.	7.69553e-135
NC_019770.1\|WP_002382766.1\|1969050_1969242_-\|hypothetical-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	8.4601e-06
NC_019770.1\|WP_002356757.1\|1966759_1967536_-\|RNA-methyltransferase	gnl\|CDD\|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	9.03482e-72
NC_019770.1\|WP_002356741.1\|1979047_1979497_-\|GatB/YqeY-domain-containing-protein	gnl\|CDD\|370480	pfam09424, YqeY, Yqey-like protein. The function of this domain found in the YqeY protein is uncertain.	1.89434e-63
NC_019770.1\|WP_002387080.1\|1979864_1980305_-\|transcriptional-repressor	gnl\|CDD\|133478	cd07153, Fur_like, Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators. Ferric uptake regulator (Fur) and related metalloregulatory proteins are iron-dependent, DNA-binding repressors and activators mainly involved in iron metabolism. A general model for Fur repression under iron-rich conditions is that activated Fur (a dimer having one Fe2+ coordinated per monomer) binds to specific DNA sequences (Fur boxes) in the promoter region of iron-responsive genes, hindering access of RNA polymerase, and repressing transcription. Positive regulation by Fur can be direct or indirect, as in the Fur repression of an anti-sense regulatory small RNA. Some members sense metal ions other than Fe2+. For example, the zinc uptake regulator (Zur) responds to Zn2+, the manganese uptake regulator (Mur) responds to Mn2+, and the nickel uptake regulator (Nur) responds to Ni2+. Other members sense signals other than metal ions. For example, PerR, a metal-dependent sensor of hydrogen peroxide. PerR regulates DNA-binding activity through metal-based protein oxidation, and co-ordinates Mn2+ or Fe2+ at its regulatory site. Fur family proteins contain an N-terminal winged-helix DNA-binding domain followed by a dimerization domain; this CD spans both those domains.	4.90593e-35
NC_019770.1\|WP_002382764.1\|1974799_1975201_-\|diacylglycerol-kinase-family-protein	gnl\|CDD\|260134	cd14265, UDPK_IM_like, Integral membrane undecaprenol kinase and similar enzymes. This mostly bacterial family of homo-trimeric integral membrane enzymes, the products of the dgkA gene, catalyzes the ATP-dependent phosphorylation of undecaprenol to undecaprenyl phosphate. C55-isoprenyl (undecaprenyl) pyroposphate acts as a scaffold for the assembly of peptidoglycan components; undecaprenol kinase (UDPK) is involved in recycling undecaprenyl units for re-use in the peptidoglycan biosynthesis. UDPK does not participate in the de-novo biosynthesis of undecaprenyl phosphate. Gram-positive bacteria have a large pool of free undecaprenol, in contrast to gram-negative bacteria. UDPK may also play a role in a stress-induced pathway that affects the function of ribosomes. In Streptococcus mutans, UDPK has been shown to be required for biofilm formation, such as in the case of smooth surface dental caries. Members of the UDPK family have low activity as diacylglycerol kinases (DAGK), and many of them are annotated as DAGKs.	5.07031e-42
NC_019770.1\|WP_002356745.1\|1975184_1975664_-\|rRNA-maturation-RNase-YbeY	gnl\|CDD\|234575	PRK00016, PRK00016, metal-binding heat shock protein; Provisional.	4.17563e-61
NC_019770.1\|WP_002389973.1\|1980403_1981261_+\|kinase/pyrophosphorylase	gnl\|CDD\|377080	pfam03618, Kinase-PPPase, Kinase/pyrophosphorylase. This family of regulatory proteins has ADP-dependent kinase and inorganic phosphate-dependent pyrophosphorylase activity.	6.32249e-139
NC_019770.1\|WP_002382765.1\|1973006_1973801_-\|DNA-repair-protein-RecO	gnl\|CDD\|273175	TIGR00613, DNA_repair_protein_RecO, DNA repair protein RecO. All proteins in this family for which functions are known are DNA binding proteins that are involved in the initiation of recombination or recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	1.19301e-71
NC_019770.1\|WP_002356759.1\|1965333_1966119_-\|30S-ribosomal-protein-S2	gnl\|CDD\|235396	PRK05299, rpsB, 30S ribosomal protein S2; Provisional.	3.78425e-167
NC_019770.1\|WP_002356740.1\|1979522_1979699_-\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	8.30263e-11
NC_019770.1\|WP_015212220.1\|1975663_1977862_-\|HDIG-domain-containing-protein	gnl\|CDD\|224397	COG1480, COG1480, Predicted membrane-associated HD superfamily hydrolase [General function prediction only].	3.77699e-159
NC_019770.1\|WP_002356760.1\|1964346_1965228_-\|elongation-factor-Ts	gnl\|CDD\|236491	PRK09377, tsf, elongation factor Ts; Provisional.	1.02636e-146
NC_019770.1\|WP_002411111.1\|1969281_1971366_-\|glycine--tRNA-ligase-subunit-beta	gnl\|CDD\|234925	PRK01233, glyS, glycyl-tRNA synthetase subunit beta; Validated.	0
NC_019770.1\|WP_002356761.1\|1963363_1964086_-\|UMP-kinase	gnl\|CDD\|239787	cd04254, AAK_UMPK-PyrH-Ec, UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and via gene repression of carbamoyl phosphate synthetase (the first enzyme of the pyrimidine biosynthesis pathway). The UMP kinase of E. coli (Ec) is known to function as a homohexamer, with GTP and UTP being allosteric effectors. Like other related enzymes (carbamate kinase, aspartokinase, and N-acetylglutamate kinase) the E. coli and most bacterial and chloroplast UMPKs (this CD) have a conserved, N-terminal, lysine residue proposed to function in the catalysis of the phosphoryl group transfer, whereas most archaeal UMPKs appear to lack this residue and the Pyrococcus furiosus structure has an additional Mg ion bound to the ATP molecule which is proposed to function as the catalysis instead. Members of this CD belong to the Amino Acid Kinase Superfamily (AAK).	1.02758e-148
NC_019770.1\|WP_002382772.1\|1966302_1966740_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|236715	PRK10562, PRK10562, putative acetyltransferase; Provisional.	1.78953e-30
NC_019770.1\|WP_002356743.1\|1977890_1978913_-\|PhoH-family-protein	gnl\|CDD\|224616	COG1702, PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms].	3.84494e-145
NC_019770.1\|WP_010706543.1\|1967642_1967918_+\|acylphosphatase	gnl\|CDD\|224174	COG1254, AcyP, Acylphosphatases [Energy production and conversion].	2.30474e-26
NC_019770.1\|WP_002359745.1\|1973883_1974786_-\|GTPase-Era	gnl\|CDD\|234624	PRK00089, era, GTPase Era; Reviewed.	0

>NC_019770.1|WP_002379669.1|1971367_1972276_-|glycine--tRNA-ligase-subunit-alpha
MKNKLTVQEMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLKLLGIDPLEHDIRFVEDNWENPSMGCAGLGWEVWLDGMEITQFTYFQQVGGLQCHPVTSEITYGLERLASYIQEVESVYDLEWTQGVKYGEIFVQPEYEHSKYSFEISNQEMLLENFDKFEKEAKRCIEESLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLARIRNMARSVAKIFVAEREKLGFPLLNKDQSVSKEAE
>NC_019770.1|WP_002411111.1|1969281_1971366_-|glycine--tRNA-ligase-subunit-beta
MAKDLLLEIGLEEMPAHVVTLSRIQLEEKVIKFLDEHHLDYETVQSFATPRRLAVKVTAIPEKQADVEEEVKGPAKKIALDAEGNWSKAAQGFVRGQGVTTEDIVFKELNGVEYVYVTKFTKGQSAKEVLTKLNDVITSLTFPVTMHWANYDFEYIRPIHWIVALLDDEVISFNVLDVTTGQTSRGHRFLGDDVTFQHANEYEAKLKEQFVVVQPNERKQMIVDQANALAAEKNWQLALDEELLEEVTNLVEYPTAFVGSFDEKYLSVPDEVLVTSMKEHQRYFEVRNDQGLLMPHFIAVRNGDNVHLENVIKGNEKVLIARLEDAEFFYNEDKKLTIEACVEKLKNVTFHEKIGSIYEKMQRVALIAQIIGRKVGLSEEELEDLKRASEIYKFDLVTNMVGEFPELQGIMGEKYALLQGEKPAVATAIREHYLPTSSEGELPETAIGAVLALADKLDSVFSFFSVGMIPTGSNDPYALRRQTYGVIRIIEDKGWTFPLVQLQTEVDEAVNQDVEKYGVLLNEGQAEVVEFVKARLRQLLMTKNVRHDIIDAVVSAEQADLSKLFASANILKSRFEDQDFKPSMEALTRVINLAKKGQELLGDTEEGIDPSLFENKAEKELYQAVNDLSEAFATRTIAENYEALVNLRPLIDAYFNETMVMVEDEKVKQNRLKQLMQIAKMALSIASLDLLIVK
>NC_019770.1|WP_002382766.1|1969050_1969242_-|hypothetical-protein
MSETTFEQILTQLSKPAVRALTNEKIDSVDELYARGRKALLSLHGFGPKSIRTIEEMTGKELK
>NC_019770.1|WP_002411113.1|1968084_1969017_+|membrane-protein-insertase-YidC
MRKLNRWLYGSGLLFLVMFLSGCVKTGADGQPTGEGFVYNFLVLPMSNAITYLVDNFNWNYGWAIIFITIIVRIIILPLGLHQSKKSFIQTEKMQAIKPQVDVAQAKMKQASTREEQMAAQAELQRIYKENNVSMVGGIGCLPLLIQMPIFSSLFFAARYTKGIATASFLGMNLGQPNMILVALAGLAYLAQGYISMIGIPEEQKKTMKSMLIVSPLMIVFMSFSSPAGVALYWVVGGIFTCIQSAITNILLRPRIKKQVQEELKNNPPKQVVTPIKDVTPKETNKVTQKTNQPKANGNNGRNAGKQKRK
>NC_019770.1|WP_010706543.1|1967642_1967918_+|acylphosphatase
MEKLRMNVQGRVQGVGFRYMTKMVADQLGVTGSVRNEDDGSVSITAIAPEDIMETFIKKIKDSPSPAGRVTYVDIQEDPLLEETEQFKVIQ
>NC_019770.1|WP_002356757.1|1966759_1967536_-|RNA-methyltransferase
MKEITSTKNNQLKEWKKLHKKKYREELNQYIIEGFHLVEEAVKANADVQWILFNQRGQQEWGTWLAEQETEKLIFVSDEVLNSLSELPTSQGILAIVTLETQQEQSLSFKGGWLLLDNIQDPGNVGTMIRTADAAGLAGVILGKGTADIYNTKVLRSMQGSHYHLPVLQRELTEVVQAFKKQGLPVFGTELNEAAIAYYEQEAVENYALILGNEGSGVSPELLAETTKNLYIPMKGQAESLNVAIAAGVLMFYFENNQ
>NC_019770.1|WP_002382772.1|1966302_1966740_-|GNAT-family-N-acetyltransferase
MLTIKKTTQLTEKELETIMAIWLQTNLEAHPFVAPTYWQENKAFVRAALPKATLILAEEEDQIIGFLGLMDNYIAGIFIKKAFQGKGIGQKLLQVAKEEQDVLSLAVYRENQAAYAFYQKQGFVQQKRTIDETGNEECHLVWQAQ
>NC_019770.1|WP_002356759.1|1965333_1966119_-|30S-ribosomal-protein-S2
MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQKTVKLVDAAYDYMKNVAEEGGVALFVGTKKQAQEAIKDEAIRAGQYYVNHRWLGGTLTNWDTIQKRIARLKKINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDVMYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITAKMADAFIEGNQGEDQATEELFVEETPEATSIEEIVDVVEGNNESAE
>NC_019770.1|WP_002356760.1|1964346_1965228_-|elongation-factor-Ts
MADVTAKMVKELRDMTGVGMMDAKKALVKVEGDMEKAVDFLRENGMAKAAKKNDRIAAEGLANVATVGNVAAIVEVNSETDFVSKNEMFQDLVKDIATKVAENKPATMEEAMAIKTEKGTIESDLIEATTVIGEKISFRRFEVVEKADNAAFGAYLHMGGRIAVLTVIDGTTDEEVAKDVAMHIAAINPRYVNESQIPQEELEHEKAVLTEQALNEGKPANIVEKMVVGRLQKFKAEIALVDQPFVKDPDMTVEKFVASKGGEVKSFVRFEVGEGIEKREDNFADEVMSQMKN
>NC_019770.1|WP_002356761.1|1963363_1964086_-|UMP-kinase
MVKPKYQRVVLKLSGEALAGEDGFGIKPPVIKEIVQEIKEVHELGIEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENLGVPTRVQTSIEMRQIAEPYIRRRAERHLEKGRVVIFAGGTGNPYFSTDTTAALRAAEVDADVILMAKNNVDGVYSADPRVDETATKFEELTHLDVISKGLQVMDSTASSLSMDNDIPLVVFNLNEAGNIRRAILGENIGTTVRGK
>NC_019770.1|WP_002382765.1|1973006_1973801_-|DNA-repair-protein-RecO
MALGETKGIILFTKDFKEKDKLVKIFTESYGKLMFFVKGAHRKNNPLLPAILPFTEAVYIGNFREEGLSFLNSSKEVQPFRNIQQDIFINAYGTYILNLVDAAIEDQHYDPNLFQFTHMALSALNEQKDPEIITNIFEIQLLERFGVRPEWHHCVACGETQGKFDYSSRYSGVLCEKHWHLDEQRYHADPRAIHFIRLFSQVSYEKVQNIQVKEETKKSIRETIDMLYDEYVGLHLKSKKFIDQMKTWENTLKIPPRKKEEKET
>NC_019770.1|WP_002359745.1|1973883_1974786_-|GTPase-Era
MTTEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNKIQGIYTIPEAQIVFIDTPGIHKPKHRLGDFMVESAYNAMREVDATLFMVSADQKRGKGDDFIIERLKNNNSPVYLIINKIDKVHPDDLLSIIEDYSKQMDFKEIIPISATEGNNFEHLMDVLVEQMPEGPQYFPDDQITDHPEYFIVSELIREKVLLLTRDEIPHSVAVVVDSMKRDENDKVHVQATIIVERDSQKGIIIGKGGKMLKQIGTKARQDIEYLLDDKVYLELWVKVQKDWRDKKIYLQDFGYRKEEY
>NC_019770.1|WP_002382764.1|1974799_1975201_-|diacylglycerol-kinase-family-protein
MALKDEQTGKNKHFINSLEFAWQGIKTVFREERNMRKHVAFGVTAIVFGFLFSLTLAEWLWLLLAVFLVWLAEIINTIFENVVDMFTDFHFHPIGKKVKDMAAGAVLLTAGFAVLVGLILFVPKILQIIQMWK
>NC_019770.1|WP_002356745.1|1975184_1975664_-|rRNA-maturation-RNase-YbeY
MDITFIDETEKVPTEEIKEIENLLQFAAGFLEIAEDTEMSVTFTDNAGIQVINRDYRGKDMPTDVISFALEDEGEDELPIIFDDEELAELPRNLGDLIISTERAAEQAVEYGHTLEREMGFLAVHGFLHLNGYDHMEPEDEKEMFGLQKEILDAYGLKR
>NC_019770.1|WP_015212220.1|1975663_1977862_-|HDIG-domain-containing-protein
MKKVLTKLGDRLGKAYLPILLAVFSLLLFMIMFGSVHQKRVEIKEGQLAEKTIRANKNIENTYETEQRKKLAAEAVTPEYIYQEDTASVQHNRIDKLFKLIDSANEKVDKEYSNKQAKAKKEETIPAPTVEERVASLKSLFESLPQDEVTFYQSFPNVFYQTIFTLTSEQLDKVRSESLMLVDDAMQNHVRESDLDKIRQEANGKIQYLDITSTMQQVIRYIVNQGIVVNDIANEKRTEELRQKAMNAVQPAMIYQGEIIVREGTQIDAKAVEKLELLGMTSQNTSIFPMVALALAILLQVEVLIFFTKQVTEPSRQRSFIIFYTGAMLISVILMKFFQIFQTEQLMYIPLFYPAAFAPLILNHFVNRRSGIIAAIFQVVFALFIFYNSIGTNSLTVILIMYLFSGFLATVVKRERMSEQVFPALMWVVVFPVFMAVVLMIYQGMSLTDGKTWTALICAGAGTVLSFLATMGLHPYIELLVTDDSMIVLNELSNPNHPLLKQLLEEAPGTYHHSMMVASLSANAVAEIGGRSLLTRVACYYHDIGKIKHANFFVENLPAGAENPHNFLLPEDSKQIIFGHVIDGAKILEEYNMPQMVIDICRQHHGTTLMKFFYVKAKERNPEIKESDFRYPGPRPQTREAGIVSIADTCEAAVRAMDHPTNEKIQAFVHNVIQDRISDGQLDECGLTMKEIRIIEKSLINGLCSTFHSRIKYPKMKAEAEEMKDEQEKRDD
>NC_019770.1|WP_002356743.1|1977890_1978913_-|PhoH-family-protein
MWYHCKGLYNKGDGRFLTDNQSKSLELILTDSDDAHMLLGTHDKHIKFLEENTHVTINSRGEVIQLIGESSEVELVASVLRALQTLIQRGIKVHTPDVVSALKMAKAGNLEAFIAMYEEEIMKDHHGRAIRIKNVGQKKYIDAVKTHDVIFGVGPAGTGKTFLAVVMAVAALKKGEVQKIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQIFGMDHTNRLMERGVIEIAPLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGFSSKMIVNGDTSQIDLPRGVTSGLVNAERTLKDIEKIAFVNFEASDVVRHPVVAQIIQAYEKEQQKHS
>NC_019770.1|WP_002356741.1|1979047_1979497_-|GatB/YqeY-domain-containing-protein
MSLLTTLNDDIKTAMKAKDKETLAVLRMLKTAIQNDQIKAGRELNGEEELTVLSREMKQRKDSLSEFEKAGRDDLVEKVKVEIAIVEKYMPQQLTEEEIRQLVQEVMTQTGATSPKDFGKVMGAMMPKVKGKADGNQVNAIVKELLQEN
>NC_019770.1|WP_002356740.1|1979522_1979699_-|30S-ribosomal-protein-S21
MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVKRKKKSEAARKRKKF
>NC_019770.1|WP_002387080.1|1979864_1980305_-|transcriptional-repressor
MAMAPVKTNIEQALETMKASGLKYTKKRELLMSYLIKRNRYVSAREVYEFMNETFKGVSYDTVYRNLHDFERLELLEKTELNGEQKFRFRCCQEVEHHHHFICTVCGKTEEIHMCPMNFFEEQLKGCSIEGHRFEILGRCADCCEK
>NC_019770.1|WP_002389973.1|1980403_1981261_+|kinase/pyrophosphorylase
MTISEEKKCVTIFVISDSAGETASKLAAASMAQYPTVDFTLIRRTFVKDEDKLVQALEDAKKAEAMVLHTIINDHLVAIANQFFNEHQLFHFDILTPPVAEIERLTGVAPMREPGALHHLNENYFKRIEAMEFAVKYDDGKDPRGFLEADVLLLGVSRTSKTPLSLFLANKNLKVANLPLIPEAHLPKQLFEMDPKKIVGLTNDPNVLNGIRKERMRAYGLPENTSYSDIEKIRRELAFANDLYQKLGCIVIDVASLSIEETASMILNALNLEDHSYYSTETAED

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Crispr_ID: NC_019770_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019770_3

2637620-2637693

Orphan

Consensus_repeat	Method
ATAGTTGGCGAGCAACAGAAAAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019770_3

>merge|NC_019770|3|2637620-2637693|CRISPRCasFinder
ATAGTTGGCGAGCAACAGAAAAACTCGATATAGAATTGGACGTAGAGCCAATAGTTGGTGAGCAACAGAAAAAC

>NC_019770|3|3|2637620-2637693|CRISPRCasFinder
ATAGTTGGCGAGCAACAGAAAAAC	TCGATATAGAATTGGACGTAGAGCCA
ATAGTTGGTGAGCAACAGAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019770.1\|WP_002389427.1\|2631849_2632560_-\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NC_019770.1\|WP_002359021.1\|2626402_2626615_-\|hypothetical-protein	unknown	unknown	unknown
NC_019770.1\|WP_002359020.1\|2626739_2627606_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|224343
NC_019770.1\|WP_002389480.1\|2640113_2640551_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NC_019770.1\|WP_002354877.1\|2632955_2633669_-\|trehalose-operon-repressor	unknown	unknown	gnl\|CDD\|274116
NC_019770.1\|WP_002389433.1\|2640683_2641238_-\|septum-formation-protein-Maf	unknown	unknown	gnl\|CDD\|238310
NC_019770.1\|WP_002389391.1\|2637759_2638353_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376232
NC_019770.1\|WP_002367458.1\|2638592_2638736_-\|putative-holin-like-toxin	unknown	unknown	gnl\|CDD\|319017
NC_019770.1\|WP_002389406.1\|2641262_2643395_-\|DNA-mismatch-repair-endonuclease-MutL	unknown	unknown	gnl\|CDD\|223400
NC_019770.1\|WP_002389419.1\|2636689_2637340_+\|beta-phosphoglucomutase	unknown	unknown	gnl\|CDD\|213672
NC_019770.1\|WP_002411259.1\|2633930_2636675_+\|glycoside-hydrolase-family-65-protein	unknown	unknown	gnl\|CDD\|224471
NC_019770.1\|WP_002354863.1\|2647420_2648977_-\|ribonuclease-Y	unknown	unknown	gnl\|CDD\|237177
NC_019770.1\|WP_002354867.1\|2643426_2646003_-\|DNA-mismatch-repair-protein-MutS	unknown	unknown	gnl\|CDD\|235444
NC_019770.1\|WP_002354864.1\|2646463_2647261_-\|TIGR00282-family-metallophosphoesterase	unknown	unknown	gnl\|CDD\|379099
NC_019770.1\|WP_002389463.1\|2631037_2631754_-\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NC_019770.1\|WP_002359008.1\|2646003_2646390_-\|YlbF-family-regulator	unknown	unknown	gnl\|CDD\|226923
NC_019770.1\|WP_002389502.1\|2629070_2630339_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NC_019770.1\|WP_002381060.1\|2638967_2639939_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NC_019770.1\|WP_002354883.1\|2630547_2630997_+\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|376605
NC_019770.1\|WP_002411262.1\|2627773_2629078_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685

Protein	Function_ID	Function_description	E-value
NC_019770.1\|WP_002389427.1\|2631849_2632560_-\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	6.13905e-14
NC_019770.1\|WP_002359020.1\|2626739_2627606_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|224343	COG1426, COG1426, Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown].	2.66641e-35
NC_019770.1\|WP_002389480.1\|2640113_2640551_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	2.21687e-92
NC_019770.1\|WP_002354877.1\|2632955_2633669_-\|trehalose-operon-repressor	gnl\|CDD\|274116	TIGR02404, Trehalose_operon_transcriptional_repressor, trehalose operon repressor, B. subtilis-type. This family consists of repressors of the GntR family typically associated with trehalose utilization operons. Trehalose is imported as trehalose-6-phosphate and then hydrolyzed by alpha,alpha-phosphotrehalase to glucose and glucose-6-P. This family includes repressors mostly from Gram-positive lineages and does not include the TreR from E. coli. [Regulatory functions, DNA interactions].	6.92052e-137
NC_019770.1\|WP_002389433.1\|2640683_2641238_-\|septum-formation-protein-Maf	gnl\|CDD\|238310	cd00555, Maf, Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.	4.27865e-85
NC_019770.1\|WP_002389391.1\|2637759_2638353_+\|hypothetical-protein	gnl\|CDD\|376232	pfam18813, PBECR4, phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4. A predicted endoRNase of the Barnase-EndoU-ColicinE5/D-RelE like nuclease fold found in polyvalent proteins of phages and conjugative elements. The predicted active site contains a conserved histidine residue.	9.04196e-24
NC_019770.1\|WP_002367458.1\|2638592_2638736_-\|putative-holin-like-toxin	gnl\|CDD\|319017	pfam16935, Hol_Tox, Putative Holin-like Toxin (Hol-Tox). Hol_Tox is a family of small proteins (34-48aas) with a single TM region. Members can exhibit antibacterial activity against Gram-positive bacteria but not against Gram-negative bacteria.	6.82893e-12
NC_019770.1\|WP_002389406.1\|2641262_2643395_-\|DNA-mismatch-repair-endonuclease-MutL	gnl\|CDD\|223400	COG0323, MutL, DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair].	0
NC_019770.1\|WP_002389419.1\|2636689_2637340_+\|beta-phosphoglucomutase	gnl\|CDD\|213672	TIGR01990, bPGM, beta-phosphoglucomutase. This model represents the beta-phosphoglucomutase enzyme which catalyzes the interconverison of beta-D-glucose-1-phosphate and beta-D-glucose-6-phosphate. The 6-phosphate is capable of non-enzymatic anomerization (alpha <-> beta) while the 1-phosphate is not. A separate enzyme is responsible for the isomerization of the alpha anomers. Beta-D-glucose-1-phosphate results from the phosphorylysis of maltose (2.4.1.8), trehalose (2.4.1.64) or trehalose-6-phosphate (2.4.1.216). Alternatively, these reactions can be run in the synthetic direction to create the disaccharides. All sequenced genomes which contain a member of this family also appear to contain at least one putative maltose or trehalose phosphorylase. Three species, Lactococcus, Enterococcus and Neisseria appear to contain a pair of paralogous beta-PGM's. Beta-phosphoglucomutase is a member of the haloacid dehalogenase superfamily of hydrolase enzymes. These enzymes are characterized by a series of three catalytic motifs positioned within an alpha-beta (Rossman) fold. beta-PGM contains an inserted alpha helical domain in between the first and second conserved motifs and thus is a member of subfamily IA of the superfamily. The third catalytic motif comes in three variants, the third of which, containing a conserved DD or ED, is the only one found here as well as in several other related enzymes (TIGR01509). The enzyme from L. lactis has been extensively characterized including a remarkable crystal structure which traps the pentacoordinate transition state. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	4.19341e-105
NC_019770.1\|WP_002411259.1\|2633930_2636675_+\|glycoside-hydrolase-family-65-protein	gnl\|CDD\|224471	COG1554, ATH1, Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism].	4.63566e-173
NC_019770.1\|WP_002354863.1\|2647420_2648977_-\|ribonuclease-Y	gnl\|CDD\|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	0
NC_019770.1\|WP_002354867.1\|2643426_2646003_-\|DNA-mismatch-repair-protein-MutS	gnl\|CDD\|235444	PRK05399, PRK05399, DNA mismatch repair protein MutS; Provisional.	0
NC_019770.1\|WP_002354864.1\|2646463_2647261_-\|TIGR00282-family-metallophosphoesterase	gnl\|CDD\|379099	pfam13277, YmdB, YmdB-like protein. This family of putative phosphoesterases contains the B. subtilis protein YmdB.	2.68643e-155
NC_019770.1\|WP_002389463.1\|2631037_2631754_-\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	6.16605e-10
NC_019770.1\|WP_002359008.1\|2646003_2646390_-\|YlbF-family-regulator	gnl\|CDD\|226923	COG4550, COG4550, Predicted membrane protein [Function unknown].	2.38925e-14
NC_019770.1\|WP_002389502.1\|2629070_2630339_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	4.40006e-52
NC_019770.1\|WP_002381060.1\|2638967_2639939_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NC_019770.1\|WP_002354883.1\|2630547_2630997_+\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	2.8499e-49
NC_019770.1\|WP_002411262.1\|2627773_2629078_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	5.84822e-85

>NC_019770.1|WP_002389419.1|2636689_2637340_+|beta-phosphoglucomutase
MTIGFIFDLDGVITDTAKFHYQAWKALADSLGIPIDETFNETLKGISRMDSLDRILAHGHRENAFIPAEKEALAQQKNDHYVQLLEHLTTEDVLPGVVPLLQQAQARHIPCAVASASKNAPLILEKLGVRAYFATIVDPDSLSKGKPDPEIFLAAADSIGVLPQNAIGFEDAQSGIDGLKAAGIYAVGLSASQPLIGADMQVSEMTELSVDALLNR
>NC_019770.1|WP_002411259.1|2633930_2636675_+|glycoside-hydrolase-family-65-protein
MSIQVHKEAPNMTILELTFATNQLTTTFFNHKLEPLHQKTFPFEALTIEETVPELCQLIVAEAAPILGGIVADFPADFFSPEETLALVPQAVIQAFAEQLNTPLLTAAEQAAAPNLLAAFEEKRQYLAWHLDYYGYVPGKNEYAVESLLTVGNGFLGLRGTTPEMTISDDHYPATYIAGLYNTAASEVAGQVVENEDFVNAPDNQHIALKIGDATDWLTISPDTLQQLHRQLNLKTGLFVAEMILKDADNQQIKLTTKKIANMAQPNDYHLQYTFEPLNFSAPITLKTVTDGSVYNYNVARYRNLTAKHFQVTALSAQENKTVIEVCTNQSNLSVRETALITGDFFEKEAIMIQEEAEKIAQVVTVMAHQGTRYTLEKQVFVQASHAEQSWQVPFTPKDSFAAAAQESARAWQTLWQQANITVTGDLMSQKLLRIHSYHLLASASPFSNQAQALDVSITARGLHGEAYRGHIFWDEIFILPFYIQHYPDTAKQLLLYRYHRLEKAKENAAASQYRGAMYPWQSGRDGRETTQKLHLNPLNGHWGEDHSILQRHVSLAIAYNAWLYWHSTQDHEFMKQYGGEMLLEIAQFWNSAATLDDATGRFFIDKVMGPDEFHEGYPDQAESGLKNNAYTNLMVVWLFEELTNILALFSEEEQAQLFAKTQTSSADLARMQQIQNSLEIEVNSDGIIAQYEGYFGLKEIDWAAMKEKYGNIYRMDRILKAEGESPDDYKVAKQADTLMLFYNLDKTRVDQILEDLGYQLPADYLEKNLLYYLKRTSHGSTLSRIVHAQLAEMAQFHELSWQLYQEALYSDYRDIQGGTTAEGIHTGVMAATIHVTLATYAGVDTRQNELSICPNLPEHWQALAFQFIHQGVTYQFSLTQTSVTITADKDTQLLVQGALIPLTAERPKEVHYQ
>NC_019770.1|WP_002354877.1|2632955_2633669_-|trehalose-operon-repressor
MNKFHDIFLELEQQIVQGDYQPGDLLPSENQLVETYNVSRETIRKALNLLINAGYIQKKQGKGSIVLNFKKFNFPISGVTSYKELQQTQHIESHTHVVSLEEIPVERNLAQLTGWTEGAPVWRLVRQREIEGEVDILDIDYLIKEIVPELPKHRAEDSIFDYLENDLGLAISYAQKEITVEPLTEMDKQLIGEVEGNHVVVVRSIMNLEDTRCFGYTESRHRLNKFKFVEFARRRKL
>NC_019770.1|WP_002389427.1|2631849_2632560_-|WxL-domain-containing-protein
MKKKIMASLLVGSAVVGASLAPLSAQAVTTGNTPVQVEFGGGMLPDAGGDPNTVRPDPGATNSNFDLIFIPREYDFGKLSISDDLTKPIPNKNDAGRNGHTEAIGIGDLRGTKEGWHVTAQSDGMKLGDESLEGNITIGVNGFYALRYDESTNQYTNQGATIDMEARPEGVNPDLWNLPLAGDAVLVANATSGKGQGIWGLSMFDTALNITTSAYNIKAGAYTGNITWNLVAGPSI
>NC_019770.1|WP_002389463.1|2631037_2631754_-|WxL-domain-containing-protein
MKKKIMASLLVSSAVVGASLAPLSAHAVTTGNTPVQAEFEAGVLPDQGDNTVGMGSVDPDPTQPNTDFDLVTIPRSFDFSPVKIGEDLTSIQAIFPSYETTRAVMVGDLRGTKEGWHVTGQLTKMNNEADELAGDINFGLEMNYAKHVTIPTDFYTVSPVLNGMNIADDPAAPSAIGTSIKIGGGATALMNATVGKGQGIWAGRFRNMTLNVTTPMQQLKKGAYTGNITWNLVAGPSI
>NC_019770.1|WP_002354883.1|2630547_2630997_+|large-conductance-mechanosensitive-channel-protein-MscL
MIKEFKEFIMRGSVLDLAVGVVIGSAFTAIVTQVVEGLITPLISLIFVLTTGKKSADDALGALVYKVEGVEFNIGSVISALITFLITAFVLFLIVKAANKMKNRGKKEEAAEEEVVPTSEDYLKEIRDLLAAQTPPAETVKTDSTFTEK
>NC_019770.1|WP_002389502.1|2629070_2630339_-|insulinase-family-protein
MSVQLVKGVNLHVIPTEKYKTVRLLVRFNTRLNHETITKRTLLSSLMETNSLNYPNQVKLSERLAELYGASFGIGVSKKGNQHWFNISMNIVNDHYLQDSQVLAEAVDFLKEIIFAPNIQAGQFEAETFQREKENLKAYLESIVEDKQTYASLALQSVYFNQSEDQKIPSFGTVAALAKETAASLAAYYQKMLAEDQVDIFVLGDVNEAELVPLFKQLPFTPREEGKAAIFYNQPIRNVIEERTEREVLAQSKLNLAYNTDIYYGDSYYFALQVFNGIFGGFPHSKLFMNVREKEHLAYYASSSIDTFRGFMTVQTGIDGKNRNQVLRLISTELENIRLGKISELEIEQTKAMLKNQYILALDNAGAWLEKEYLNQLMPQTMLTAEEWIARINAVTIPEIQEVAKRLELQAIFFLEGETEND
>NC_019770.1|WP_002411262.1|2627773_2629078_-|insulinase-family-protein
MIKKDYAQIKETLYTETLENGLKVYLLPKNDFQKTYGLFTTDYGSIDNTFVPIGQEEMIEVPDGIAHFLEHKMFEKEDGDVFQKFGQQGASANAFTSFTKTSYLFSTTDQVTQNLETLLDFVQSPYFTKETVEKEKGIIGQEIQMYLDDPNWRLFFGILGNLYPKHPLHIDIAGTVASIAEITAEDLYTCYNTFYHPSNMTLFVVGKMDPEALMAFIRENQAAKEFPAAQPIRRHFPEETAADIVKESAIEMAVTRAKVLVGLKGLDEVPTTGRDLMKYQVTVNLLLQLLFGNTSQNYLALYDEGLLDDSFSYDFNLDRSFHFADIGGDSEQPEVLAERIEAILLSATTSPELTEENLSLLKKKMIGKYFQSLNSLEYIANQFSQSLFGETTLFDKIEVIESIQLADVRQVAETLIREEGLSRFYMYPKGETEQ
>NC_019770.1|WP_002359020.1|2626739_2627606_-|helix-turn-helix-domain-containing-protein
MASVNIGETLKEARLQKNISIDELQQMTKIQKRYLEIIEQNDFESLPGTFYVRAFIRQYASAVGLDGNQLVDIYDGKEPAIVEEPKPVYEELEGSRKQLHDEEKQSSWLLRNLPAIAFSLIGLAIAVVVLYIMWQDQKAEPIIQTPATSASVEKPKESSQAPESSTQSSTPPSSSSEPEKKTAVAVVSDANNQVTATVKDANSPINITFKGTEGSCWIGVMVDGNYTYQHTLQAGETQTTALPANAANATLILGASNNVAIQVDGADLTLEKTPVLIRKDVTLGITYR
>NC_019770.1|WP_002359021.1|2626402_2626615_-|hypothetical-protein
MLKIVNKKFNLITIFSIALLVMGFLIVGLQLYFYFIYGSKFLDSITLIGMINLGLGYYQLFLKKGKNISE
>NC_019770.1|WP_002389391.1|2637759_2638353_+|hypothetical-protein
MIEKKDFDTIRKAFLIYDTNFNNHMFTYTYQHRKTKKLLEMNVQFEAGNFMHLCGVDYYQIDKQGSCKFRFKATQFYRALKNNKVSLRGIKPKDDGTTGQKLQVIPLLEMLISPGVRVCDGGKFYNLQYEKAIRSGKMIVALTCKENNKKYVPQSLLSLINQPRKSQSKSLTESHEVIKISKSELNSTSVIEVYDKF
>NC_019770.1|WP_002367458.1|2638592_2638736_-|putative-holin-like-toxin
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK
>NC_019770.1|WP_002381060.1|2638967_2639939_-|ribose-phosphate-diphosphokinase
MSKHYFDPRLKIFSLNSNRPLAEKIADAVGVELGKCSVTQFSDGEIQVNIEESIRGAHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYARQDRKARAREPITAKLVANMIEKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIADYFIEHGIQGDDVVVVSPDHGGVTRARKLAEFLKAPIAIIDKRRPKANVAEVMNIIGHVEGKTCVLIDDMIDTAGTISLAANALKEAGAKDVYASCTHPVLSGPALQRIEDSAIERLVVTDSIYLSDDRKIAKIDEVSVGELIGDAIKRIHENKPVSPLFETKNK
>NC_019770.1|WP_002389480.1|2640113_2640551_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MTKPTEEELKQTLTDLQYAVTQENATERPFSGEYDDFYQDGIYVDIVSGEPLFSSLDKYDAGCGWPSFTKPIEKRGVKEKADFSHGMHRVEVRSQEADSHLGHVFTDGPLQEGDLRYCINAAALRFVPVADLEKEGYGEYLSLFK
>NC_019770.1|WP_002389433.1|2640683_2641238_-|septum-formation-protein-Maf
MQIILASQSPRRQELLKRVVPTFTIAPADIDETVGKDGLPAEYVAQMAAQKAAAIAEQSPEALVIGCDTIVALAGEILGKPTSREDGYRMLRLLSGKTHDVYTSVTLKQGEKERSATVHSTVTFYPLTETEIHAYLDTAEYADKAGAYGIQGQGALLIEAIAGDYYAIMGLPIAKVARLLKEFN
>NC_019770.1|WP_002389406.1|2641262_2643395_-|DNA-mismatch-repair-endonuclease-MutL
MGKIQELSEQLANQIAAGEVVERPASVVKELVENALDAGSTQIDIFIEEAGLKTIQIIDNGEGIAKEDVLNAFKRHATSKIHTRDDLFRIRSLGFRGEALPSIASVSEMIVETATAEEEEGSYVILKGGKVEENRPAALRKGTKMTVSNLFYNTPARLKYVKTIQTELANIGDIVNRLALSHPKVAFRLVHDGHKMMSTTGNGDLKQTIAGIYGISTAKKMLKIEGKDLDFTLTGYVSLPEVTRASRNYLSTIINGRYIKNFALNKAIVAGYGSKLMVGRFPIAVLEIEMDPLLVDVNVHPTKQEVRLSKEKDLMALIEQAIQEVLSQEQLIPNAADNLRFKKKLPPEPKAEQMEIPLSTEQPAVKQRPGSLSYNPATGRFYAEHATDETPASSAPESVNQTERAVDPMDDPFAPPVPESTSVAEETSAYETSSAAVDSANHWETASNEQQVIAEETKITEVSDSEPSLRSSEAADEVFQEEMKLHPEFDANSAASQRELKQALNKLEEERPTERFPELEYFGQMHGTYLFAQSKDGLFIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPIVIDYPNSDALKIKEQKETLAEVGIHLEDFGQNSFIVRAHPTWYPAGEEESIVREMIDMLLTTGSVSVKKFREATAIMMSCKRSIKANHYLNEQQARVLLKDLALCENPFNCPHGRPVLIHFTNSDMERMFKRIQDPH
>NC_019770.1|WP_002354867.1|2643426_2646003_-|DNA-mismatch-repair-protein-MutS
MPQKTKNTPMMEQYLSIKAQYKDAFLFYRLGDFYELFYEDAINAAQILELTLTSRNRNADDPIPMCGVPYHAAQGYIDTLIEQGYKVAICEQVEDPKTTKGMVKREVVQLVTPGTVMNSKGLEAKDNNYLTAVLTDGNQFGFAYVDLSTGELKTAVLADEEGVLNEASALQTKEMVLGSGIPESLKENLSLRLNIIFSTQETVEENAEFSFLTNELINPLEIEITGKLLSYLSVTQKRSLSHIQKAVEYQPDHFLKMDHYSKFNLELSQSIRTGQKKGTLLWLLDETKTAMGGRLLKQWLDRPLIQERQIKARQEMVQSLLNAYFERLDLQAALTNVYDLERLAGRVAFGSVNGRDLIQLRTSLEQVPTIRQLIVGINQGEWDDLLVDLNPVEDLVALIATAINEEAPLQITEGNVIKDGYNDQLDEYRDAMRNGKQWLAELEAKERQETGIKNLKIGYNRVFGYFIEITKSNLANLEEGKYERKQTLANAERFITPELKELERLILEAEEKSVELEYQLFLAVREQVKTNIDRLQTLAKTISAVDVLQSFATISERYQYVRPTLRSNTKNLAIVEGRHPVVEKVLGHQEYIPNSIRMNPETDILLITGPNMSGKSTYMRQLALTVVMAQIGCFVPAESAEMPIFDQIFTRIGASDDLIAGQSTFMVEMMEANQALRHATPNSLILFDELGRGTATYDGMALAQAIIEYIHREVQAKTLFSTHYHELTVLDETLKGLKNIHVGAVEKDGEVVFLHKMMEGPADKSYGIHVAKIAGLPSPLLERAATILSALEAEETTIPSSVHHEEVSEVHEETEQLSLFKEVSTEELSVIDTLKKMNLLEMTPLDALNMLHQLQKRI
>NC_019770.1|WP_002359008.1|2646003_2646390_-|YlbF-family-regulator
MKVKKMEPLNLDAQSNKELEKLLHLIGQDEVIQRYQAIEEKVKKNKKLTELVEEIKAAQKDAVQFAHYGKPTAEKEAIQRADAKTKEFDEHPLVVAYREQLIEANDLVQHVTALIQYRVNEELEKEGN
>NC_019770.1|WP_002354864.1|2646463_2647261_-|TIGR00282-family-metallophosphoesterase
MRILFIGDVVGSLGREALATYVPKLKKKYRPQVTIANGENAASGRGITGKIYKKFLQDGVDVVTMGNHTWDNKDIFEFIDDAKKMVRPANFPEDVPGQGMVFVKVNQLELAVINLQARTFMVPLEDPFKKAAELVAIARKRTPLIFVDFHGETTSEKQAMSWFLDGQVSAVVGTHTHVQTNDARILPKGTAFLSDVGMTGPYDGILGMKREPIIEKFMTALPKRFEVVETGRTILSACILEIDDQTGQAKMIEPIQISEDRPFQE
>NC_019770.1|WP_002354863.1|2647420_2648977_-|ribonuclease-Y
MVLNILLAIVGLIVGLGLGFVIAKSRHDKAINGAKISASSILENARKESETLKKEALLEAKEENQKYRSEIESELKESRLELKSQENRLIQREQTLDRKDDSLEKREGSLEEKEEKLGARQQLIDEREKEVENLINQQHQELERIASLSKEEAKSIIMKSTEEELNHELTLMVKESEQRAKEESDRKAKNLLSLAIQRCAADSVSETTVSVVTLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGRIHPARIEEMVEKSRKEMDERIREYGEQAAFEVGAHTLHPDLIKILGRLRFRTSYGQNVLNHSIEVAKLAGVLAAELGEDVQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYKENSVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLENLENISNSFEGVDSSFAVQAGREVRVMVKPEEISDLESVRLVRDIRKKIEDDLDYPGHIKVTVIRETRAVDYAK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	MF157411	Escherichia coli strain EC1000 plasmid pCR2, complete sequence	304-333	0	1.0
NC_019770_1	1.5\|1761047\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761047-1761076	30	MK721192	Enterococcus phage vB_EfaM_Ef2.3, complete genome	137117-137146	0	1.0
NC_019770_1	1.5\|1761047\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761047-1761076	30	CAJDJZ010000002	Enterococcus phage vB_EfaH_149 genome assembly, contig: phage149-genome, whole genome shotgun sequence	104693-104722	0	1.0
NC_019770_1	1.5\|1761047\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761047-1761076	30	AP018714	Enterococcus phage phiEF17H DNA, complete sequence	102448-102477	0	1.0
NC_019770_1	1.5\|1761047\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761047-1761076	30	CAJDJY010000002	Enterococcus phage 156 genome assembly, contig: phage156-genome, whole genome shotgun sequence	100911-100940	0	1.0
NC_019770_1	1.5\|1761047\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761047-1761076	30	LR031359	Enterococcus phage 156, complete genome	100911-100940	0	1.0
NC_019770_1	1.10\|1760810\|24\|NC_019770\|PILER-CR	1760810-1760833	24	MF157411	Escherichia coli strain EC1000 plasmid pCR2, complete sequence	310-333	0	1.0
NC_019770_1	1.4\|1760981\|30\|NC_019770\|CRISPRCasFinder,CRT	1760981-1761010	30	GQ478087	Enterococcus phage phiFL3B, complete genome	19318-19347	1	0.967
NC_019770_1	1.4\|1760981\|30\|NC_019770\|CRISPRCasFinder,CRT	1760981-1761010	30	GQ478082	Enterococcus phage phiFL1B, complete genome	17335-17364	2	0.933
NC_019770_1	1.4\|1760981\|30\|NC_019770\|CRISPRCasFinder,CRT	1760981-1761010	30	GQ478083	Enterococcus phage phiFL1C, complete genome	17070-17099	2	0.933
NC_019770_1	1.4\|1760981\|30\|NC_019770\|CRISPRCasFinder,CRT	1760981-1761010	30	NC_013646	Enterococcus phage phiFL1A, complete genome	17088-17117	2	0.933
NC_019770_1	1.10\|1760810\|24\|NC_019770\|PILER-CR	1760810-1760833	24	MK496783	Capybara microvirus Cap3_SP_410, complete genome	3418-3441	2	0.917
NC_019770_1	1.11\|1760885\|21\|NC_019770\|PILER-CR	1760885-1760905	21	NZ_KY940428	UNVERIFIED: Bacillus sp. (in: Bacteria) strain PUMK-07 plasmid pMK-07, complete sequence	92495-92515	2	0.905
NC_019770_1	1.11\|1760885\|21\|NC_019770\|PILER-CR	1760885-1760905	21	NZ_CP041978	Bacillus pacificus strain NCCP 15909 plasmid unnamed1, complete sequence	298209-298229	2	0.905
NC_019770_1	1.11\|1760885\|21\|NC_019770\|PILER-CR	1760885-1760905	21	NC_011655	Bacillus cereus AH187 plasmid pAH187_270, complete sequence	68118-68138	2	0.905
NC_019770_1	1.11\|1760885\|21\|NC_019770\|PILER-CR	1760885-1760905	21	NC_010924	Bacillus cereus strain AH187 plasmid pCER270, complete sequence	124527-124547	2	0.905
NC_019770_1	1.11\|1760885\|21\|NC_019770\|PILER-CR	1760885-1760905	21	CP045776	Bacillus paranthracis strain CFSAN068816 plasmid p1CFSAN068816, complete sequence	113842-113862	2	0.905
NC_019770_1	1.11\|1760885\|21\|NC_019770\|PILER-CR	1760885-1760905	21	CP041980	Bacillus paranthracis strain NCCP 15910 plasmid unnamed, complete sequence	281212-281232	2	0.905
NC_019770_1	1.11\|1760885\|21\|NC_019770\|PILER-CR	1760885-1760905	21	NC_016792	Bacillus cereus NC7401 plasmid pNCcld, complete sequence	123396-123416	2	0.905
NC_019770_1	1.11\|1760885\|21\|NC_019770\|PILER-CR	1760885-1760905	21	NZ_CP053657	Bacillus cereus strain CTMA_1571 plasmid p.1, complete sequence	393148-393168	2	0.905
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	AP014314	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S31-C24, * SEQUENCING IN PROGRESS *	4200-4229	5	0.833
NC_019770_1	1.9\|1761311\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761311-1761340	30	NZ_CP040452	Halomonas sp. PA16-9 plasmid p_unnamed1, complete sequence	483626-483655	5	0.833
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	MK496783	Capybara microvirus Cap3_SP_410, complete genome	3412-3441	6	0.8
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	MN693358	Marine virus AFVG_25M395, complete genome	6141-6170	6	0.8
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	MN694190	Marine virus AFVG_250M608, complete genome	30089-30118	6	0.8
NC_019770_1	1.4\|1760981\|30\|NC_019770\|CRISPRCasFinder,CRT	1760981-1761010	30	MH450115	Arthrobacter phage Breylor17, complete genome	15795-15824	6	0.8
NC_019770_1	1.4\|1760981\|30\|NC_019770\|CRISPRCasFinder,CRT	1760981-1761010	30	MF038791	Arthrobacter phage ElephantMan, complete genome	15819-15848	6	0.8
NC_019770_1	1.4\|1760981\|30\|NC_019770\|CRISPRCasFinder,CRT	1760981-1761010	30	MF038790	Arthrobacter phage Niktson, complete genome	15819-15848	6	0.8
NC_019770_1	1.4\|1760981\|30\|NC_019770\|CRISPRCasFinder,CRT	1760981-1761010	30	MF140432	Arthrobacter phage Teacup, complete genome	15091-15120	6	0.8
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	176473-176502	6	0.8
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP018132	Enterococcus faecium strain A_020709_82 plasmid unnamed4, complete sequence	1959-1988	6	0.8
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP014531	Enterococcus faecium strain E745 plasmid pl2, complete sequence	20018-20047	6	0.8
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NC_014502	Gloeothece verrucosa PCC 7822 plasmid Cy782203, complete sequence	268334-268363	7	0.767
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP032754	Lactobacillus plantarum subsp. argentoratensis strain DSM 16365 plasmid unnamed3, complete sequence	26827-26856	7	0.767
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	NZ_CP024469	Shigella dysenteriae strain BU53M1 plasmid unnamed3, complete sequence	113562-113591	7	0.767
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	NC_007607	Shigella dysenteriae Sd197 plasmid pSD1_197, complete sequence	48404-48433	7	0.767
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	NC_022899	Shigella dysenteriae 1617 plasmid pSLG231, complete sequence	47293-47322	7	0.767
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	NZ_CP026779	Shigella dysenteriae strain 69-3818 plasmid unnamed2, complete sequence	130694-130723	7	0.767
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	NZ_CP026783	Shigella dysenteriae strain 08-3380 plasmid unnamed, complete sequence	80950-80979	7	0.767
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	NZ_CP026775	Shigella dysenteriae strain ATCC 13313 plasmid unnamed, complete sequence	177833-177862	7	0.767
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	NZ_CP026781	Shigella dysenteriae strain 53-3937 plasmid unnamed	27523-27552	7	0.767
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	NZ_CP026879	Shigella dysenteriae strain 07-3308 plasmid unnamed, complete sequence	40421-40450	7	0.767
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	NZ_CP026785	Shigella dysenteriae strain 80-547 plasmid unnamed	93328-93357	7	0.767
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	AP019525	Tenacibaculum phage PTm5 DNA, complete genome	191857-191886	7	0.767
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	AP019524	Tenacibaculum phage PTm1 DNA, complete genome	190796-190825	7	0.767
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	NZ_LR214939	Mycoplasma salivarium strain NCTC10113 plasmid 2	365691-365720	7	0.767
NC_019770_1	1.4\|1760981\|30\|NC_019770\|CRISPRCasFinder,CRT	1760981-1761010	30	NZ_CP031540	Lactococcus lactis subsp. cremoris strain 3107 plasmid p3107B, complete sequence	43565-43594	7	0.767
NC_019770_1	1.4\|1760981\|30\|NC_019770\|CRISPRCasFinder,CRT	1760981-1761010	30	NZ_CP016729	Lactococcus lactis subsp. cremoris strain JM4 plasmid pJM4A, complete sequence	43565-43594	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP018832	Enterococcus faecium strain ISMMS_VRE_9 plasmid p1_ISMMS_VRE9, complete sequence	133390-133419	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_LR135253	Enterococcus faecium isolate E6988 plasmid 11	1671-1700	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP017798	Enterococcus faecium strain E243 plasmid unnamed1, complete sequence	94732-94761	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP017793	Enterococcus faecium strain E240 plasmid unnamed1, complete sequence	94732-94761	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP023790	Enterococcus faecium strain Efaecium_ER04462.3A plasmid pER04462.3A.1, complete sequence	153448-153477	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP023800	Enterococcus faecium strain Efaecium_ER04526.5A plasmid pER04526.5A.1, complete sequence	156920-156949	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP023809	Enterococcus faecium strain Efaecium_ER04526.3A plasmid pER04562.3A.1, complete sequence	156933-156962	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP023805	Enterococcus faecium strain Efaecium_ER04619.3A isolate isolate plasmid pER04619.3A.1, complete sequence	155587-155616	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP018827	Enterococcus faecium strain ISMMS_VRE_12 plasmid p1_ISMMS_VRE12, complete sequence	133390-133419	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP023795	Enterococcus faecium strain Efaecium_ER04484.3A plasmid pER04484.3A.1, complete sequence	156933-156962	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP023781	Enterococcus faecium strain Efaecium_ER03933.3A isolate isolate plasmid pER93933.3A.1, complete sequence	154256-154285	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP028875	Borreliella bavariensis PBi plasmid lp28-4_cp32-1, complete sequence	48566-48595	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NC_021990	Enterococcus faecium Aus0085 plasmid p6, complete sequence	159-188	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP044281	Enterococcus faecium strain V2937 plasmid pHVH-V2937-7, complete sequence	1177-1206	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP039703	Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence	464549-464578	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP013238	Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence	580997-581026	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP039706	Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence	215391-215420	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP033246	Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence	797842-797871	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP033248	Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence	797858-797887	7	0.767
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_AP019717	Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence	214186-214215	7	0.767
NC_019770_1	1.7\|1761179\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761179-1761208	30	MG592671	Vibrio phage 2.275.O._10N.286.54.E11, partial genome	255026-255055	7	0.767
NC_019770_1	1.8\|1761245\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761245-1761274	30	NZ_CP018322	Alteromonas macleodii strain Te101 plasmid pTE101a, complete sequence	202687-202716	7	0.767
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP028270	Pediococcus pentosaceus strain SRCM102740 plasmid unnamed1, complete sequence	22740-22769	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP028267	Pediococcus pentosaceus strain SRCM102739 plasmid unnamed1, complete sequence	9446-9475	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP015919	Pediococcus pentosaceus strain wikim20 plasmid pKPP01, complete sequence	11178-11207	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP021931	Lactobacillus plantarum strain TMW 1.1308 plasmid pL11308-1, complete sequence	27801-27830	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP024059	Lactobacillus plantarum strain KACC 92189 plasmid unnamed1	53320-53349	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP028265	Pediococcus pentosaceus strain SRCM102738 plasmid unnamed1, complete sequence	32031-32060	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP018326	Lactobacillus plantarum subsp. plantarum strain TS12 plasmid pLP12-2, complete sequence	38976-39005	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP019582	Lactobacillus helveticus strain LH5 plasmid pCBTLH5_1, complete sequence	10189-10218	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP035308	Lactobacillus helveticus strain IDCC3801 plasmid pHel23910, complete sequence	20537-20566	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP029972	Lactobacillus kefiri strain DH5 plasmid pDH5, complete sequence	6123-6152	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP029967	Lactobacillus curvatus strain ZJUNIT8 plasmid pnunamed1, complete sequence	28417-28446	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	LT615366	Enterococcus phage VPE25 genome assembly, chromosome: VPE25	14742-14771	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	LT546029	Enterococcus phage VFW genome assembly, chromosome: VFW	14675-14704	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	LT546030	Enterococcus phage VPE25 genome assembly, chromosome: I	14742-14771	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	MT119360	Enterococcus phage nattely, complete genome	14821-14850	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP037431	Lactobacillus plantarum strain EM plasmid pEM2, complete sequence	20908-20937	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP025692	Lactobacillus plantarum strain IRG1 plasmid pIRG102, complete sequence	133-162	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP035559	Lactobacillus plantarum strain SRCM103297 plasmid unnamed3	24727-24756	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP035572	Lactobacillus plantarum strain SRCM103303 plasmid unnamed1	22589-22618	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP035175	Lactobacillus plantarum strain SRCM103426 plasmid unnamed1	87952-87981	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP018327	Lactobacillus plantarum subsp. plantarum strain TS12 plasmid pLP12-3, complete sequence	992-1021	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP035116	Lactobacillus plantarum strain SRCM103295 plasmid unnamed3	94597-94626	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP018798	Lactobacillus parabuchneri strain FAM21731 plasmid pFAM21731.2, complete sequence	27103-27132	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP025415	Lactobacillus plantarum strain X7021 plasmid unnamed3, complete sequence	13215-13244	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP021928	Pediococcus pentosaceus strain SRCM100194 plasmid pPP194-2, complete sequence	6938-6967	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP035145	Lactobacillus plantarum strain SRCM103357 plasmid unnamed2	36987-37016	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP050806	Lactobacillus plantarum strain SPC-SNU 72-2 plasmid pLBP752, complete sequence	19494-19523	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP028277	Lactobacillus plantarum strain SRCM100995 plasmid unnamed2, complete sequence	54324-54353	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP013152	Lactobacillus plantarum strain MF1298 plasmid pMF1298-4, complete sequence	22761-22790	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	MT119361	Enterococus phage vipetofem, complete genome	70537-70566	8	0.733
NC_019770_1	1.2\|1760849\|30\|NC_019770\|CRISPRCasFinder,CRT	1760849-1760878	30	KT932701	Enterococcus phage vB_EfaS_IME196, complete genome	10922-10951	8	0.733
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	NZ_CP013139	Pseudoalteromonas sp. Bsw20308 plasmid pPBSW1, complete sequence	811833-811862	8	0.733
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	NZ_CP047122	Lactobacillus hilgardii strain FLUB plasmid unnamed1	39415-39444	9	0.7
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	KM359505	Prochlorococcus phage P-TIM68, complete genome	108590-108619	9	0.7
NC_019770_1	1.1\|1760783\|30\|NC_019770\|CRISPRCasFinder,CRT	1760783-1760812	30	KY971610	Pseudomonas phage PspYZU05, complete genome	121642-121671	9	0.7
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	AP013736	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C32A-MedDCM-OCT-S46-C31, * SEQUENCING IN PROGRESS *	21605-21634	9	0.7
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	AP013730	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C32A-MedDCM-OCT-S30-C21, * SEQUENCING IN PROGRESS *	25701-25730	9	0.7
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	AP013733	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C32A-MedDCM-OCT-S37-C24, * SEQUENCING IN PROGRESS *	33052-33081	9	0.7
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	AP013444	Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C32A-MedDCM-OCT-S40-C23	18147-18176	9	0.7
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	AP013734	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C32A-MedDCM-OCT-S39-C27, * SEQUENCING IN PROGRESS *	11646-11675	9	0.7
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	AP013735	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C32A-MedDCM-OCT-S43-C92, * SEQUENCING IN PROGRESS *	21847-21876	9	0.7
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	AP013732	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C32A-MedDCM-OCT-S32-C182, * SEQUENCING IN PROGRESS *	6431-6460	9	0.7
NC_019770_1	1.3\|1760915\|30\|NC_019770\|CRISPRCasFinder,CRT	1760915-1760944	30	AP013729	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C32A-MedDCM-OCT-S27-C31, * SEQUENCING IN PROGRESS *	3159-3188	9	0.7
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP028869	Borreliella garinii strain 20047 plasmid lp28-7, complete sequence	2440-2469	9	0.7
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP017215	Borreliella burgdorferi strain B331 plasmid B331_lp28_6, complete sequence	2490-2519	9	0.7
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP018749	Borreliella garinii strain CIP 103362 isolate 20047 plasmid lp28-7	24650-24679	9	0.7
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NC_017408	Borreliella burgdorferi JD1 plasmid JD1 lp28-6, complete sequence	24337-24366	9	0.7
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NC_015915	Borreliella bissettii DN127 plasmid lp17, complete sequence	24790-24819	9	0.7
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NC_015918	Borreliella bissettii DN127 plasmid lp28-7, complete sequence	28196-28225	9	0.7
NC_019770_1	1.6\|1761113\|30\|NC_019770\|CRISPRCasFinder,CRT,PILER-CR	1761113-1761142	30	NZ_CP028874	Borreliella bavariensis PBi plasmid lp25_cp32-3, complete sequence	52710-52739	9	0.7

1. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to MF157411 (Escherichia coli strain EC1000 plasmid pCR2, complete sequence) position: , mismatch: 0, identity: 1.0

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aggggagaaaaagccaaatcaaaaaagttt	Protospacer
******************************

2. spacer 1.5|1761047|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to MK721192 (Enterococcus phage vB_EfaM_Ef2.3, complete genome) position: , mismatch: 0, identity: 1.0

tctggtaaattcttaatgtctgcataggta	CRISPR spacer
tctggtaaattcttaatgtctgcataggta	Protospacer
******************************

3. spacer 1.5|1761047|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to CAJDJZ010000002 (Enterococcus phage vB_EfaH_149 genome assembly, contig: phage149-genome, whole genome shotgun sequence) position: , mismatch: 0, identity: 1.0

tctggtaaattcttaatgtctgcataggta	CRISPR spacer
tctggtaaattcttaatgtctgcataggta	Protospacer
******************************

4. spacer 1.5|1761047|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to AP018714 (Enterococcus phage phiEF17H DNA, complete sequence) position: , mismatch: 0, identity: 1.0

tctggtaaattcttaatgtctgcataggta	CRISPR spacer
tctggtaaattcttaatgtctgcataggta	Protospacer
******************************

5. spacer 1.5|1761047|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to CAJDJY010000002 (Enterococcus phage 156 genome assembly, contig: phage156-genome, whole genome shotgun sequence) position: , mismatch: 0, identity: 1.0

tctggtaaattcttaatgtctgcataggta	CRISPR spacer
tctggtaaattcttaatgtctgcataggta	Protospacer
******************************

6. spacer 1.5|1761047|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to LR031359 (Enterococcus phage 156, complete genome) position: , mismatch: 0, identity: 1.0

tctggtaaattcttaatgtctgcataggta	CRISPR spacer
tctggtaaattcttaatgtctgcataggta	Protospacer
******************************

7. spacer 1.10|1760810|24|NC_019770|PILER-CR matches to MF157411 (Escherichia coli strain EC1000 plasmid pCR2, complete sequence) position: , mismatch: 0, identity: 1.0

aggggagaaaaagccaaatcaaaa	CRISPR spacer
aggggagaaaaagccaaatcaaaa	Protospacer
************************

8. spacer 1.4|1760981|30|NC_019770|CRISPRCasFinder,CRT matches to GQ478087 (Enterococcus phage phiFL3B, complete genome) position: , mismatch: 1, identity: 0.967

atgaactaaatgtttcagattctcaaataa	CRISPR spacer
atgaattaaatgtttcagattctcaaataa	Protospacer
*****.************************

9. spacer 1.4|1760981|30|NC_019770|CRISPRCasFinder,CRT matches to GQ478082 (Enterococcus phage phiFL1B, complete genome) position: , mismatch: 2, identity: 0.933

atgaactaaatgtttcagattctcaaataa	CRISPR spacer
atgaattaaatgtttcagattcccaaataa	Protospacer
*****.****************.*******

10. spacer 1.4|1760981|30|NC_019770|CRISPRCasFinder,CRT matches to GQ478083 (Enterococcus phage phiFL1C, complete genome) position: , mismatch: 2, identity: 0.933

atgaactaaatgtttcagattctcaaataa	CRISPR spacer
atgaattaaatgtttcagattcccaaataa	Protospacer
*****.****************.*******

11. spacer 1.4|1760981|30|NC_019770|CRISPRCasFinder,CRT matches to NC_013646 (Enterococcus phage phiFL1A, complete genome) position: , mismatch: 2, identity: 0.933

atgaactaaatgtttcagattctcaaataa	CRISPR spacer
atgaattaaatgtttcagattcccaaataa	Protospacer
*****.****************.*******

12. spacer 1.10|1760810|24|NC_019770|PILER-CR matches to MK496783 (Capybara microvirus Cap3_SP_410, complete genome) position: , mismatch: 2, identity: 0.917

aggggagaaaaagccaaatcaaaa	CRISPR spacer
agggcagaaaaagccaaatcaaga	Protospacer
**** *****************.*

13. spacer 1.11|1760885|21|NC_019770|PILER-CR matches to NZ_KY940428 (UNVERIFIED: Bacillus sp. (in: Bacteria) strain PUMK-07 plasmid pMK-07, complete sequence) position: , mismatch: 2, identity: 0.905

aattgaagccttaacaagtaa	CRISPR spacer
tgttgaagccttaacaagtaa	Protospacer
 .*******************

14. spacer 1.11|1760885|21|NC_019770|PILER-CR matches to NZ_CP041978 (Bacillus pacificus strain NCCP 15909 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.905

aattgaagccttaacaagtaa	CRISPR spacer
tgttgaagccttaacaagtaa	Protospacer
 .*******************

15. spacer 1.11|1760885|21|NC_019770|PILER-CR matches to NC_011655 (Bacillus cereus AH187 plasmid pAH187_270, complete sequence) position: , mismatch: 2, identity: 0.905

aattgaagccttaacaagtaa	CRISPR spacer
tgttgaagccttaacaagtaa	Protospacer
 .*******************

16. spacer 1.11|1760885|21|NC_019770|PILER-CR matches to NC_010924 (Bacillus cereus strain AH187 plasmid pCER270, complete sequence) position: , mismatch: 2, identity: 0.905

aattgaagccttaacaagtaa	CRISPR spacer
tgttgaagccttaacaagtaa	Protospacer
 .*******************

17. spacer 1.11|1760885|21|NC_019770|PILER-CR matches to CP045776 (Bacillus paranthracis strain CFSAN068816 plasmid p1CFSAN068816, complete sequence) position: , mismatch: 2, identity: 0.905

aattgaagccttaacaagtaa	CRISPR spacer
tgttgaagccttaacaagtaa	Protospacer
 .*******************

18. spacer 1.11|1760885|21|NC_019770|PILER-CR matches to CP041980 (Bacillus paranthracis strain NCCP 15910 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.905

aattgaagccttaacaagtaa	CRISPR spacer
tgttgaagccttaacaagtaa	Protospacer
 .*******************

19. spacer 1.11|1760885|21|NC_019770|PILER-CR matches to NC_016792 (Bacillus cereus NC7401 plasmid pNCcld, complete sequence) position: , mismatch: 2, identity: 0.905

aattgaagccttaacaagtaa	CRISPR spacer
tgttgaagccttaacaagtaa	Protospacer
 .*******************

20. spacer 1.11|1760885|21|NC_019770|PILER-CR matches to NZ_CP053657 (Bacillus cereus strain CTMA_1571 plasmid p.1, complete sequence) position: , mismatch: 2, identity: 0.905

aattgaagccttaacaagtaa	CRISPR spacer
tgttgaagccttaacaagtaa	Protospacer
 .*******************

21. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to AP014314 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S31-C24, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 5, identity: 0.833

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
ttgttgattttggtgcttatgaatcaaaag	Protospacer
.* ************** *** *******

22. spacer 1.9|1761311|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040452 (Halomonas sp. PA16-9 plasmid p_unnamed1, complete sequence) position: , mismatch: 5, identity: 0.833

agaaagtggggaatgcgtaatgccgtactt-	CRISPR spacer
ggaaagtggagaaagcgtaatgcc-tgcttc	Protospacer
.********.*** ********** *.***

23. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to MK496783 (Capybara microvirus Cap3_SP_410, complete genome) position: , mismatch: 6, identity: 0.8

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
agggcagaaaaagccaaatcaagaattatc	Protospacer
**** *****************.**   *.

24. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to MN693358 (Marine virus AFVG_25M395, complete genome) position: , mismatch: 6, identity: 0.8

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aacgcacaaaaagcccaatcaaaaaagatt	Protospacer
*. * * ******** *********** **

25. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to MN694190 (Marine virus AFVG_250M608, complete genome) position: , mismatch: 6, identity: 0.8

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
tggagtgcgaaagccaaatcaaaaaaggtt	Protospacer
 **.* * .****************** **

26. spacer 1.4|1760981|30|NC_019770|CRISPRCasFinder,CRT matches to MH450115 (Arthrobacter phage Breylor17, complete genome) position: , mismatch: 6, identity: 0.8

atgaactaaatgtttcagattctcaaataa	CRISPR spacer
aacaactcaatggttcagattctcaaacat	Protospacer
*  **** **** **************.*

27. spacer 1.4|1760981|30|NC_019770|CRISPRCasFinder,CRT matches to MF038791 (Arthrobacter phage ElephantMan, complete genome) position: , mismatch: 6, identity: 0.8

atgaactaaatgtttcagattctcaaataa	CRISPR spacer
aacaactcaatggttcagattctcaaacat	Protospacer
*  **** **** **************.*

28. spacer 1.4|1760981|30|NC_019770|CRISPRCasFinder,CRT matches to MF038790 (Arthrobacter phage Niktson, complete genome) position: , mismatch: 6, identity: 0.8

atgaactaaatgtttcagattctcaaataa	CRISPR spacer
aacaactcaatggttcagattctcaaacat	Protospacer
*  **** **** **************.*

29. spacer 1.4|1760981|30|NC_019770|CRISPRCasFinder,CRT matches to MF140432 (Arthrobacter phage Teacup, complete genome) position: , mismatch: 6, identity: 0.8

atgaactaaatgtttcagattctcaaataa	CRISPR spacer
aacaactcaatggttcagattctcaaacat	Protospacer
*  **** **** **************.*

30. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 6, identity: 0.8

tagcctaaaattaatacatcattttcgata	CRISPR spacer
tctgcaaaaattagtaaatcattttcgata	Protospacer
*   * *******.** *************

31. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018132 (Enterococcus faecium strain A_020709_82 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.8

tagcctaaaattaatacatcattttcgata	CRISPR spacer
aagtctaaaatcaatacatcattttgagta	Protospacer
 **.*******.************* ..**

32. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014531 (Enterococcus faecium strain E745 plasmid pl2, complete sequence) position: , mismatch: 6, identity: 0.8

tagcctaaaattaatacatcattttcgata	CRISPR spacer
aagtctaaaatcaatacatcattttgagta	Protospacer
 **.*******.************* ..**

33. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NC_014502 (Gloeothece verrucosa PCC 7822 plasmid Cy782203, complete sequence) position: , mismatch: 7, identity: 0.767

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aatcaacaaaaagccaaaacaaaaaagtta	Protospacer
*.  .* *********** **********

34. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP032754 (Lactobacillus plantarum subsp. argentoratensis strain DSM 16365 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.767

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaatttct	Protospacer
*.  ********* ***********  *.*

35. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP024469 (Shigella dysenteriae strain BU53M1 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.767

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
ctgttgattttggtgcaaatgcatatatga	Protospacer
** ************* *******  * .

36. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to NC_007607 (Shigella dysenteriae Sd197 plasmid pSD1_197, complete sequence) position: , mismatch: 7, identity: 0.767

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
ctgttgattttggtgcaaatgcatatatga	Protospacer
** ************* *******  * .

37. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to NC_022899 (Shigella dysenteriae 1617 plasmid pSLG231, complete sequence) position: , mismatch: 7, identity: 0.767

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
ctgttgattttggtgcaaatgcatatatga	Protospacer
** ************* *******  * .

38. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP026779 (Shigella dysenteriae strain 69-3818 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
ctgttgattttggtgcaaatgcatatatga	Protospacer
** ************* *******  * .

39. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP026783 (Shigella dysenteriae strain 08-3380 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
ctgttgattttggtgcaaatgcatatatga	Protospacer
** ************* *******  * .

40. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP026775 (Shigella dysenteriae strain ATCC 13313 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
ctgttgattttggtgcaaatgcatatatga	Protospacer
** ************* *******  * .

41. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP026781 (Shigella dysenteriae strain 53-3937 plasmid unnamed) position: , mismatch: 7, identity: 0.767

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
ctgttgattttggtgcaaatgcatatatga	Protospacer
** ************* *******  * .

42. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP026879 (Shigella dysenteriae strain 07-3308 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
ctgttgattttggtgcaaatgcatatatga	Protospacer
** ************* *******  * .

43. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP026785 (Shigella dysenteriae strain 80-547 plasmid unnamed) position: , mismatch: 7, identity: 0.767

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
ctgttgattttggtgcaaatgcatatatga	Protospacer
** ************* *******  * .

44. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to AP019525 (Tenacibaculum phage PTm5 DNA, complete genome) position: , mismatch: 7, identity: 0.767

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
attttgactttggtgctaatgcaattaatg	Protospacer
 ******.*************** . **

45. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to AP019524 (Tenacibaculum phage PTm1 DNA, complete genome) position: , mismatch: 7, identity: 0.767

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
attttgactttggtgctaatgcaattaatg	Protospacer
 ******.*************** . **

46. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_LR214939 (Mycoplasma salivarium strain NCTC10113 plasmid 2) position: , mismatch: 7, identity: 0.767

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
ttgctcgtttttctgctaatgcatcaaaat	Protospacer
.* .* .****  *****************

47. spacer 1.4|1760981|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP031540 (Lactococcus lactis subsp. cremoris strain 3107 plasmid p3107B, complete sequence) position: , mismatch: 7, identity: 0.767

atgaactaaatgtttcagattctcaaataa	CRISPR spacer
ctaaagaaaatgtttcagattctccaattg	Protospacer
 *.**  ***************** *** .

48. spacer 1.4|1760981|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP016729 (Lactococcus lactis subsp. cremoris strain JM4 plasmid pJM4A, complete sequence) position: , mismatch: 7, identity: 0.767

atgaactaaatgtttcagattctcaaataa	CRISPR spacer
ctaaagaaaatgtttcagattctccaattg	Protospacer
 *.**  ***************** *** .

49. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018832 (Enterococcus faecium strain ISMMS_VRE_9 plasmid p1_ISMMS_VRE9, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
aagtctaaaatcaatacatcattttgcgtg	Protospacer
 **.*******.*************  .*.

50. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR135253 (Enterococcus faecium isolate E6988 plasmid 11) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
aagtctaaaatcaatacatcattttgcgtg	Protospacer
 **.*******.*************  .*.

51. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017798 (Enterococcus faecium strain E243 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
aagtctaaaatcaatacatcattttgcgtg	Protospacer
 **.*******.*************  .*.

52. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017793 (Enterococcus faecium strain E240 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
aagtctaaaatcaatacatcattttgcgtg	Protospacer
 **.*******.*************  .*.

53. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023790 (Enterococcus faecium strain Efaecium_ER04462.3A plasmid pER04462.3A.1, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
aagtctaaaatcaatacatcattttgcgtg	Protospacer
 **.*******.*************  .*.

54. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023800 (Enterococcus faecium strain Efaecium_ER04526.5A plasmid pER04526.5A.1, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
aagtctaaaatcaatacatcattttgcgtg	Protospacer
 **.*******.*************  .*.

55. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023809 (Enterococcus faecium strain Efaecium_ER04526.3A plasmid pER04562.3A.1, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
aagtctaaaatcaatacatcattttgcgtg	Protospacer
 **.*******.*************  .*.

56. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023805 (Enterococcus faecium strain Efaecium_ER04619.3A isolate isolate plasmid pER04619.3A.1, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
aagtctaaaatcaatacatcattttgcgtg	Protospacer
 **.*******.*************  .*.

57. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018827 (Enterococcus faecium strain ISMMS_VRE_12 plasmid p1_ISMMS_VRE12, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
aagtctaaaatcaatacatcattttgcgtg	Protospacer
 **.*******.*************  .*.

58. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023795 (Enterococcus faecium strain Efaecium_ER04484.3A plasmid pER04484.3A.1, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
aagtctaaaatcaatacatcattttgcgtg	Protospacer
 **.*******.*************  .*.

59. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023781 (Enterococcus faecium strain Efaecium_ER03933.3A isolate isolate plasmid pER93933.3A.1, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
aagtctaaaatcaatacatcattttgcgtg	Protospacer
 **.*******.*************  .*.

60. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028875 (Borreliella bavariensis PBi plasmid lp28-4_cp32-1, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
tatcctaaaattaatacatcacttctactc	Protospacer
** ******************.**... *

61. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NC_021990 (Enterococcus faecium Aus0085 plasmid p6, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
aagtctaaaatcaatacatcattttgcgtg	Protospacer
 **.*******.*************  .*.

62. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044281 (Enterococcus faecium strain V2937 plasmid pHVH-V2937-7, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
aagtctaaaatcaatacatcattttgcgtg	Protospacer
 **.*******.*************  .*.

63. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039703 (Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
tcatctaaaattaatacataattttggtca	Protospacer
* ..*************** ***** * .*

64. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013238 (Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
tcatctaaaattaatacataattttggtca	Protospacer
* ..*************** ***** * .*

65. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039706 (Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
tcatctaaaattaatacataattttggtca	Protospacer
* ..*************** ***** * .*

66. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033246 (Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
tcatctaaaattaatacataattttggtca	Protospacer
* ..*************** ***** * .*

67. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033248 (Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
tcatctaaaattaatacataattttggtca	Protospacer
* ..*************** ***** * .*

68. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP019717 (Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence) position: , mismatch: 7, identity: 0.767

tagcctaaaattaatacatcattttcgata	CRISPR spacer
tcatctaaaattaatacataattttggtca	Protospacer
* ..*************** ***** * .*

69. spacer 1.7|1761179|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to MG592671 (Vibrio phage 2.275.O._10N.286.54.E11, partial genome) position: , mismatch: 7, identity: 0.767

ataccatccgcagttggtgtaagttcggtt	CRISPR spacer
ctaccacccgcagttggtgtaagtttccaa	Protospacer
 *****.******************.

70. spacer 1.8|1761245|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018322 (Alteromonas macleodii strain Te101 plasmid pTE101a, complete sequence) position: , mismatch: 7, identity: 0.767

atgactatgcgaaagttaat-cgtttgttac	CRISPR spacer
atgcctatgcgaaagttaatccgaataatg-	Protospacer
*** **************** **  *. *.

71. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP028270 (Pediococcus pentosaceus strain SRCM102740 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

72. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP028267 (Pediococcus pentosaceus strain SRCM102739 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

73. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP015919 (Pediococcus pentosaceus strain wikim20 plasmid pKPP01, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

74. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP021931 (Lactobacillus plantarum strain TMW 1.1308 plasmid pL11308-1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

75. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP024059 (Lactobacillus plantarum strain KACC 92189 plasmid unnamed1) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

76. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP028265 (Pediococcus pentosaceus strain SRCM102738 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

77. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP018326 (Lactobacillus plantarum subsp. plantarum strain TS12 plasmid pLP12-2, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

78. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP019582 (Lactobacillus helveticus strain LH5 plasmid pCBTLH5_1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

79. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP035308 (Lactobacillus helveticus strain IDCC3801 plasmid pHel23910, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

80. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP029972 (Lactobacillus kefiri strain DH5 plasmid pDH5, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

81. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP029967 (Lactobacillus curvatus strain ZJUNIT8 plasmid pnunamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

82. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to LT615366 (Enterococcus phage VPE25 genome assembly, chromosome: VPE25) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
cgaaaagaaaaagccaaatcacaagagtag	Protospacer
 *...**************** **.***

83. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to LT546029 (Enterococcus phage VFW genome assembly, chromosome: VFW) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
cgaaaagaaaaagccaaatcacaagagtag	Protospacer
 *...**************** **.***

84. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to LT546030 (Enterococcus phage VPE25 genome assembly, chromosome: I) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
cgaaaagaaaaagccaaatcacaagagtag	Protospacer
 *...**************** **.***

85. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to MT119360 (Enterococcus phage nattely, complete genome) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
cgaaaagaaaaagccaaatcacaagagtag	Protospacer
 *...**************** **.***

86. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP037431 (Lactobacillus plantarum strain EM plasmid pEM2, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

87. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP025692 (Lactobacillus plantarum strain IRG1 plasmid pIRG102, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

88. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP035559 (Lactobacillus plantarum strain SRCM103297 plasmid unnamed3) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

89. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP035572 (Lactobacillus plantarum strain SRCM103303 plasmid unnamed1) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

90. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP035175 (Lactobacillus plantarum strain SRCM103426 plasmid unnamed1) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

91. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP018327 (Lactobacillus plantarum subsp. plantarum strain TS12 plasmid pLP12-3, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

92. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP035116 (Lactobacillus plantarum strain SRCM103295 plasmid unnamed3) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

93. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP018798 (Lactobacillus parabuchneri strain FAM21731 plasmid pFAM21731.2, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

94. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP025415 (Lactobacillus plantarum strain X7021 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

95. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP021928 (Pediococcus pentosaceus strain SRCM100194 plasmid pPP194-2, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

96. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP035145 (Lactobacillus plantarum strain SRCM103357 plasmid unnamed2) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

97. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP050806 (Lactobacillus plantarum strain SPC-SNU 72-2 plasmid pLBP752, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

98. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP028277 (Lactobacillus plantarum strain SRCM100995 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

99. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP013152 (Lactobacillus plantarum strain MF1298 plasmid pMF1298-4, complete sequence) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
aattgagaaaaaggcaaatcaaaaattcct	Protospacer
*.  ********* ***********  ..*

100. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to MT119361 (Enterococus phage vipetofem, complete genome) position: , mismatch: 8, identity: 0.733

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
cgaaaagaaaaagccaaatcacaagagtag	Protospacer
 *...**************** **.***

101. spacer 1.2|1760849|30|NC_019770|CRISPRCasFinder,CRT matches to KT932701 (Enterococcus phage vB_EfaS_IME196, complete genome) position: , mismatch: 8, identity: 0.733

gaattgataattgaagccttaacaagtaat	CRISPR spacer
caggtgatattttaagccttaacaagttgg	Protospacer
 *. ***** ** ************** .

102. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP013139 (Pseudoalteromonas sp. Bsw20308 plasmid pPBSW1, complete sequence) position: , mismatch: 8, identity: 0.733

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
ttaaccgttttggtgctaatgcttcaaaag	Protospacer
.*  . .*************** ******

103. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to NZ_CP047122 (Lactobacillus hilgardii strain FLUB plasmid unnamed1) position: , mismatch: 9, identity: 0.7

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
taacatctcaaagccaaatcaaaaaagttt	Protospacer
 .. .    *********************

104. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to KM359505 (Prochlorococcus phage P-TIM68, complete genome) position: , mismatch: 9, identity: 0.7

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
caaagagaaaaagcaaaattaaaaaaggaa	Protospacer
 ...********** ****.*******

105. spacer 1.1|1760783|30|NC_019770|CRISPRCasFinder,CRT matches to KY971610 (Pseudomonas phage PspYZU05, complete genome) position: , mismatch: 9, identity: 0.7

aggggagaaaaagccaaatcaaaaaagttt	CRISPR spacer
gaaagagaaaaagcaaaatcaaaaacctaa	Protospacer
....********** **********  *

106. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to AP013736 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C32A-MedDCM-OCT-S46-C31, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.7

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
taaatgattgtggtgctaatgcatctttac	Protospacer
.   ***** ***************   *.

107. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to AP013730 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C32A-MedDCM-OCT-S30-C21, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.7

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
taaatgattgtggtgctaatgcatctttac	Protospacer
.   ***** ***************   *.

108. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to AP013733 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C32A-MedDCM-OCT-S37-C24, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.7

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
taaatgattgtggtgctaatgcatctttac	Protospacer
.   ***** ***************   *.

109. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to AP013444 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C32A-MedDCM-OCT-S40-C23) position: , mismatch: 9, identity: 0.7

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
taaatgattgtggtgctaatgcatctttac	Protospacer
.   ***** ***************   *.

110. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to AP013734 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C32A-MedDCM-OCT-S39-C27, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.7

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
taaatgattgtggtgctaatgcatctttac	Protospacer
.   ***** ***************   *.

111. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to AP013735 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C32A-MedDCM-OCT-S43-C92, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.7

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
taaatgattgtggtgctaatgcatctttac	Protospacer
.   ***** ***************   *.

112. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to AP013732 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C32A-MedDCM-OCT-S32-C182, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.7

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
taaatgattgtggtgctaatgcatctttac	Protospacer
.   ***** ***************   *.

113. spacer 1.3|1760915|30|NC_019770|CRISPRCasFinder,CRT matches to AP013729 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C32A-MedDCM-OCT-S27-C31, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.7

cttttgattttggtgctaatgcatcaaaat	CRISPR spacer
taaatgattgtggtgctaatgcatctttac	Protospacer
.   ***** ***************   *.

114. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028869 (Borreliella garinii strain 20047 plasmid lp28-7, complete sequence) position: , mismatch: 9, identity: 0.7

tagcctaaaattaatacatcattttcgata	CRISPR spacer
tatcctaaaattaatacatcactcctttct	Protospacer
** ******************.*...  .

115. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017215 (Borreliella burgdorferi strain B331 plasmid B331_lp28_6, complete sequence) position: , mismatch: 9, identity: 0.7

tagcctaaaattaatacatcattttcgata	CRISPR spacer
tatcctaaaattaatacatcactcctttct	Protospacer
** ******************.*...  .

116. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018749 (Borreliella garinii strain CIP 103362 isolate 20047 plasmid lp28-7) position: , mismatch: 9, identity: 0.7

tagcctaaaattaatacatcattttcgata	CRISPR spacer
tatcctaaaattaatacatcactcctttct	Protospacer
** ******************.*...  .

117. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NC_017408 (Borreliella burgdorferi JD1 plasmid JD1 lp28-6, complete sequence) position: , mismatch: 9, identity: 0.7

tagcctaaaattaatacatcattttcgata	CRISPR spacer
tatcctaaaattaatacatcactcctttct	Protospacer
** ******************.*...  .

118. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NC_015915 (Borreliella bissettii DN127 plasmid lp17, complete sequence) position: , mismatch: 9, identity: 0.7

tagcctaaaattaatacatcattttcgata	CRISPR spacer
tatcctaaaattaatacatcactcctttct	Protospacer
** ******************.*...  .

119. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NC_015918 (Borreliella bissettii DN127 plasmid lp28-7, complete sequence) position: , mismatch: 9, identity: 0.7

tagcctaaaattaatacatcattttcgata	CRISPR spacer
tatcctaaaattaatacatcactcctttct	Protospacer
** ******************.*...  .

120. spacer 1.6|1761113|30|NC_019770|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028874 (Borreliella bavariensis PBi plasmid lp25_cp32-3, complete sequence) position: , mismatch: 9, identity: 0.7

tagcctaaaattaatacatcattttcgata	CRISPR spacer
tatcctaaaattaatacatcactcctttct	Protospacer
** ******************.*...  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

377676 : 485103

Streptococcus_phage(35.48%)

integrase,holin,protease,transposase,tRNA

attL 373840:373856|attR 469441:469458

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
373840:373856	attL	NA	NA	NA	NA
WP_002358446.1\|377676_378846_-\|integrase	site-specific integrase	A0A1B0T6A8	Bacillus_phage	4.6e-31	28.6
373840:373856	attL	NA	NA	NA	NA
WP_002355366.1\|378889_379120_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002358448.1\|379975_380221_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002364925.1\|380214_380616_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_096001397.1\|382568_383731_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.8e-75	49.1
WP_002389521.1\|383799_384456_-	zeta toxin family protein	NA	NA	NA	NA
WP_000301765.1\|384457_384730_-	antitoxin	A0A1X9I6E5	Streptococcus_phage	5.0e-05	100.0
WP_002389526.1\|384746_384956_-	peptide-binding protein	A0A1X9I6D5	Streptococcus_phage	2.0e-30	97.1
WP_096001398.1\|385025_385922_-	ParA family protein	A0A1X9I765	Streptococcus_phage	1.4e-152	98.2
WP_002363033.1\|386310_387594_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
387401:387417	attR	NA	NA	NA	NA
WP_002389507.1\|387610_388537_-	hypothetical protein	NA	NA	NA	NA
387401:387417	attR	NA	NA	NA	NA
WP_002389508.1\|388713_389442_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002389544.1\|389548_390406_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_002389568.1\|390436_391117_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	2.6e-119	90.7
WP_002387834.1\|392374_392557_-\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_002389697.1\|392634_392985_-	hypothetical protein	NA	NA	NA	NA
WP_002389579.1\|393062_394703_-	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_002365872.1\|394703_395060_-	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_002389681.1\|395305_395578_-	hypothetical protein	NA	NA	NA	NA
WP_002389657.1\|395610_397770_-	toprim domain-containing protein	NA	NA	NA	NA
WP_010708982.1\|397827_398124_-	hypothetical protein	NA	NA	NA	NA
WP_002389722.1\|398101_398437_-	hypothetical protein	NA	NA	NA	NA
WP_002389552.1\|398453_400277_-	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_002389582.1\|400276_400762_-	PcfB family protein	NA	NA	NA	NA
WP_002389585.1\|400921_401530_-	hypothetical protein	NA	NA	NA	NA
WP_002365866.1\|401513_401759_-	hypothetical protein	NA	NA	NA	NA
WP_002389533.1\|401745_402372_-	hypothetical protein	NA	NA	NA	NA
WP_002389719.1\|402395_405011_-	CHAP domain-containing protein	A0A1X9I9L1	Staphylococcus_phage	8.9e-06	32.2
WP_002389583.1\|405022_407413_-	hypothetical protein	NA	NA	NA	NA
WP_002367919.1\|407366_407720_-	PrgI family protein	NA	NA	NA	NA
WP_002387740.1\|408526_408823_-	hypothetical protein	NA	NA	NA	NA
WP_002365858.1\|408836_409064_-	hypothetical protein	NA	NA	NA	NA
WP_002367916.1\|409110_409545_-	hypothetical protein	Q38339	Lactococcus_phage	5.9e-16	37.5
WP_002367915.1\|409564_410464_-	hypothetical protein	NA	NA	NA	NA
WP_002389703.1\|410505_411363_-	pheromone response LPXTG-anchored adhesin PrgC	NA	NA	NA	NA
WP_002367913.1\|411390_411744_-	pheromone response system RNA-binding regulator PrgU	NA	NA	NA	NA
WP_002367912.1\|411805_415699_-	LPXTG-anchored aggregation substance	NA	NA	NA	NA
WP_096001399.1\|415935_417097_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	7.8e-79	50.9
WP_002355369.1\|417543_418581_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_002335374.1\|418606_419545_-	2-dehydropantoate 2-reductase	NA	NA	NA	NA
WP_002385303.1\|420070_420670_+\|integrase	tyrosine-type recombinase/integrase	D2XR58	Bacillus_phage	2.5e-28	35.6
WP_002385302.1\|420937_422341_+	hypothetical protein	NA	NA	NA	NA
WP_002388844.1\|422474_423434_-\|transposase	IS30-like element IS1062 family transposase	H7BW61	unidentified_phage	6.3e-10	26.1
WP_002389373.1\|424176_424818_-	MFS transporter	NA	NA	NA	NA
WP_010708992.1\|424857_426387_-	multicopper oxidase domain-containing protein	NA	NA	NA	NA
WP_096001400.1\|426667_427349_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	7.7e-111	85.0
WP_002384805.1\|428005_429685_+	D-lactate dehydrogenase	NA	NA	NA	NA
WP_096001401.1\|429787_431160_-\|transposase	IS3-like element ISLla3 family transposase	A0A1B1P773	Bacillus_phage	1.1e-55	43.8
WP_002355383.1\|431542_432892_-	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	5.8e-118	51.4
WP_002355386.1\|433029_433653_-	cysteine hydrolase	NA	NA	NA	NA
WP_002384811.1\|433679_433844_-	hypothetical protein	NA	NA	NA	NA
WP_002355388.1\|433917_434508_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_042341262.1\|434847_435108_+	DUF3102 domain-containing protein	J7KDG2	Streptococcus_phage	1.4e-12	49.4
WP_002355390.1\|435257_435782_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	4.3e-21	38.6
WP_002389371.1\|435782_436136_+\|transposase	transposase	NA	NA	NA	NA
WP_002355391.1\|436251_436593_-	hypothetical protein	NA	NA	NA	NA
WP_002389382.1\|436711_437653_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_002389379.1\|437697_438957_-\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_002386104.1\|439258_439411_-	hypothetical protein	NA	NA	NA	NA
WP_002355395.1\|439511_439748_+	helix-turn-helix transcriptional regulator	A0A097PBE6	Streptococcus_pyogenes_phage	1.6e-12	50.7
WP_015212159.1\|440166_442281_+\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	1.5e-117	38.9
WP_045009080.1\|444965_445511_-	SOS response-associated peptidase family protein	A0A1P8CX02	Bacillus_phage	5.2e-09	33.6
WP_002389517.1\|445515_446505_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	8.7e-55	39.3
WP_002389522.1\|446790_447162_-	hypothetical protein	NA	NA	NA	NA
WP_002389523.1\|447163_447967_-	ParA family protein	A0A0K2FLP4	Brevibacillus_phage	1.4e-10	26.0
WP_010709001.1\|447930_449607_+	type IA DNA topoisomerase	A0A1X9I6W8	Streptococcus_phage	5.4e-267	98.0
WP_096001402.1\|449822_450985_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.0e-78	50.9
WP_015212161.1\|451092_451947_+	ParA family protein	A0A1X9I765	Streptococcus_phage	2.3e-152	97.9
WP_002355411.1\|452017_452233_+	peptide-binding protein	A0A1X9I6D5	Streptococcus_phage	2.1e-30	95.7
WP_002355414.1\|452523_452832_+	zeta toxin family protein	NA	NA	NA	NA
WP_071623404.1\|452911_453340_-\|integrase	tyrosine-type recombinase/integrase	W6LMU7	Streptococcus_phage	5.8e-16	35.7
WP_002355416.1\|453889_454657_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_002355418.1\|455145_455571_+	galactose-6-phosphate isomerase subunit LacA	NA	NA	NA	NA
WP_002345825.1\|455587_456103_+	galactose-6-phosphate isomerase subunit LacB	NA	NA	NA	NA
WP_002363040.1\|456113_457046_+	tagatose-6-phosphate kinase	NA	NA	NA	NA
WP_002355420.1\|457048_458029_+	tagatose-bisphosphate aldolase	NA	NA	NA	NA
WP_002290550.1\|458056_458374_+	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_002343085.1\|458373_460080_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_002290548.1\|460226_461633_+	6-phospho-beta-galactosidase	NA	NA	NA	NA
WP_002355422.1\|461655_461928_+	DUF3884 family protein	NA	NA	NA	NA
WP_002355424.1\|461948_462848_+	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_002389513.1\|463284_463893_+	zeta toxin family protein	NA	NA	NA	NA
WP_002384822.1\|463840_464119_-	recombinase family protein	NA	NA	NA	NA
WP_002363045.1\|464106_464427_-	recombinase family protein	A0A219Y912	Aeromonas_phage	5.5e-19	45.1
WP_002355428.1\|468044_469019_+	choloylglycine hydrolase family protein	M1H001	Paramecium_bursaria_Chlorella_virus	2.1e-24	31.6
WP_015212162.1\|469443_470403_-\|transposase	IS30-like element IS1062 family transposase	H7BW61	unidentified_phage	1.1e-09	26.1
WP_002355429.1\|470857_471322_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_002307675.1\|471314_471611_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_002355431.1\|472195_473038_-	MATE family efflux transporter	NA	NA	NA	NA
WP_002355432.1\|473383_474052_+	2,3-diphosphoglycerate-dependent phosphoglycerate mutase	NA	NA	NA	NA
WP_002355434.1\|474154_474421_+	ACT domain-containing protein	NA	NA	NA	NA
WP_002384854.1\|474435_475779_+	PFL family protein	NA	NA	NA	NA
WP_077933103.1\|475854_476379_+\|transposase	transposase	NA	NA	NA	NA
WP_002331389.1\|476694_477144_-	DIP1984 family protein	NA	NA	NA	NA
WP_002361212.1\|480193_481033_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	4.0e-69	48.5
WP_002355441.1\|481055_481538_+	VOC family protein	NA	NA	NA	NA
WP_002361214.1\|481703_483149_+	cardiolipin synthase	NA	NA	NA	NA
WP_002355444.1\|483846_485103_+\|tRNA	tyrosine--tRNA ligase	A0A1L2CUL7	Pectobacterium_phage	1.7e-79	40.3

DBSCAN-SWA_2

760080 : 768000

Planktothrix_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002355794.1\|760080_761139_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-17	30.1
WP_002361357.1\|761138_762095_+	ATP-binding cassette domain-containing protein	A0A1J0FA64	Only_Syngen_Nebraska_virus	4.2e-06	23.9
WP_002388929.1\|762135_763206_+	helix-turn-helix domain-containing protein	A0A288TXV8	Enterococcus_phage	9.9e-89	49.0
WP_002355797.1\|763604_764126_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	3.0e-14	33.3
WP_002355798.1\|764239_764440_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_002355799.1\|764500_764860_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_002409311.1\|764906_765287_-	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_002388939.1\|765354_765714_+	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_002364710.1\|765781_766276_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002361365.1\|766293_766809_+	GrpB family protein	A0A2K5B2B6	Erysipelothrix_phage	7.7e-39	48.8
WP_002380126.1\|766824_768000_-	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	3.3e-85	47.7

DBSCAN-SWA_3

1126953 : 1190042

Enterococcus_phage(27.27%)

holin,tRNA,tail,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002357859.1\|1126953_1129350_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	1.7e-19	24.1
WP_002360497.1\|1129374_1129725_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_002393873.1\|1129807_1130038_+	hypothetical protein	NA	NA	NA	NA
WP_002382232.1\|1130097_1130583_-	toxin	A0A097BY56	Enterococcus_phage	4.4e-60	70.5
WP_002357856.1\|1130617_1131100_-	helix-turn-helix transcriptional regulator	R9QTP6	Staphylococcus_phage	1.2e-20	48.6
WP_002392532.1\|1131496_1132252_+	DnaD domain protein	A0A0K0MX39	Streptococcus_phage	8.7e-31	56.0
WP_002381951.1\|1132270_1133113_+	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	2.6e-31	31.0
WP_002357852.1\|1133179_1133572_+	hypothetical protein	NA	NA	NA	NA
WP_002357851.1\|1133591_1133999_+	RinA family phage transcriptional activator	NA	NA	NA	NA
WP_002382237.1\|1134220_1134637_+	hypothetical protein	NA	NA	NA	NA
WP_002381948.1\|1134649_1135162_+\|tail	phage major tail protein, TP901-1 family	W6LP72	Streptococcus_phage	8.8e-35	49.4
WP_002357848.1\|1135194_1135554_+	hypothetical protein	A0A0F6N4J9	Staphylococcus_phage	7.6e-09	32.2
WP_002392533.1\|1135646_1135940_+	hypothetical protein	NA	NA	NA	NA
WP_002388921.1\|1135929_1138863_+	hypothetical protein	W8EBC4	Geobacillus_phage	6.9e-15	41.2
WP_002365553.1\|1138864_1139791_+\|tail	phage tail family protein	C9E2K5	Enterococcus_phage	9.0e-147	78.6
WP_002357844.1\|1139803_1141261_+\|tail	phage tail protein	C9E2K6	Enterococcus_phage	9.5e-175	47.7
WP_002357843.1\|1141293_1143063_+	hypothetical protein	A0A097BYA8	Enterococcus_phage	1.8e-143	72.3
WP_002357842.1\|1143086_1143482_+\|holin	phage holin family protein	F0PIJ6	Enterococcus_phage	2.8e-33	48.9
WP_041161887.1\|1143600_1144725_+	SH3 domain-containing protein	A0A139ZVY1	Enterococcus_phage	4.1e-77	44.3
WP_002406331.1\|1144878_1145799_+\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_002361698.1\|1145824_1146775_+	riboflavin biosynthesis protein RibF	NA	NA	NA	NA
WP_002361699.1\|1146774_1147371_+	N-acetyltransferase	A0A1P8CWJ6	Bacillus_phage	1.5e-22	37.1
WP_002357837.1\|1147520_1147844_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_002361700.1\|1147847_1148189_+	DUF1048 domain-containing protein	NA	NA	NA	NA
WP_002360471.1\|1148213_1148474_+	DUF2087 domain-containing protein	NA	NA	NA	NA
WP_002357834.1\|1148632_1149808_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_002357833.1\|1149773_1150922_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_002357832.1\|1150983_1151871_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002382245.1\|1151894_1152770_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002410013.1\|1153306_1155967_+	magnesium-translocating P-type ATPase	M1HXH2	Paramecium_bursaria_Chlorella_virus	1.7e-44	24.1
WP_002410012.1\|1156210_1157359_+	oxygen-independent coproporphyrinogen III oxidase	NA	NA	NA	NA
WP_002357828.1\|1157584_1158628_+	heat-inducible transcriptional repressor HrcA	NA	NA	NA	NA
WP_002357827.1\|1158682_1159222_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_002357825.1\|1159281_1161111_+	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	4.6e-134	48.3
WP_002357822.1\|1161402_1162572_+	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	2.7e-23	26.0
WP_015212179.1\|1162810_1163545_+	serine/threonine protein phosphatase	A7KV25	Bacillus_phage	3.6e-13	31.8
WP_002366578.1\|1163642_1165835_+	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
WP_002382248.1\|1165837_1166323_+	SprT family protein	NA	NA	NA	NA
WP_002357817.1\|1166721_1167939_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_002357816.1\|1168004_1168181_-	hypothetical protein	NA	NA	NA	NA
WP_015212180.1\|1168358_1169186_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002363827.1\|1169286_1170435_+	N-acetylglucosamine-6-phosphate deacetylase	NA	NA	NA	NA
WP_002360464.1\|1170478_1170865_-	hypothetical protein	NA	NA	NA	NA
WP_002388942.1\|1170878_1171538_-	DNA/RNA non-specific endonuclease	NA	NA	NA	NA
WP_002363831.1\|1171698_1172400_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.9e-36	38.6
WP_002363832.1\|1172400_1175046_+	ABC transporter permease	NA	NA	NA	NA
WP_002357809.1\|1175229_1175763_+	hypothetical protein	NA	NA	NA	NA
WP_002357808.1\|1175779_1177249_+	flotillin family protein	NA	NA	NA	NA
WP_002388890.1\|1177395_1177629_+	DUF2969 domain-containing protein	NA	NA	NA	NA
WP_002357804.1\|1178041_1178221_+	hypothetical protein	NA	NA	NA	NA
WP_002357803.1\|1178276_1178888_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_002388807.1\|1179063_1183311_+	2-hydroxyacyl-CoA dehydratase	NA	NA	NA	NA
WP_002357800.1\|1183516_1184224_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_007209349.1\|1184537_1185710_-\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	6.3e-121	88.4
WP_002388846.1\|1186358_1187213_+	ThiF family adenylyltransferase	A0A1V0SAV8	Catovirus	2.3e-11	30.8
WP_002363835.1\|1187176_1188049_+	hypothetical protein	NA	NA	NA	NA
WP_002388944.1\|1188071_1189016_+	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	3.2e-14	31.3
WP_002395903.1\|1189133_1190042_+\|transposase	IS982-like element ISEfm1 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

1533593 : 1580641

Enterococcus_phage(46.15%)

plate,tail,integrase,holin,portal,capsid,terminase,tRNA

attL 1556710:1556731|attR 1585201:1585222

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002384452.1\|1533593_1534109_-\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
WP_010824699.1\|1534105_1534867_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	5.7e-22	31.4
WP_002364054.1\|1535022_1536807_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.0e-45	27.2
WP_015212189.1\|1536806_1538558_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	4.5e-54	31.2
WP_002357397.1\|1538755_1538974_-	YneF family protein	NA	NA	NA	NA
WP_002357396.1\|1539168_1540062_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	1.9e-24	32.2
WP_002364059.1\|1540072_1540540_-	DUF1801 domain-containing protein	NA	NA	NA	NA
WP_002364060.1\|1540539_1541202_-	YdeI/OmpD-associated family protein	NA	NA	NA	NA
WP_002357393.1\|1541601_1541850_+	hypothetical protein	A0A097BYB1	Enterococcus_phage	2.1e-34	91.5
WP_002357392.1\|1542177_1543014_-	hypothetical protein	A0A1S5PRZ0	Streptococcus_phage	2.7e-65	53.6
WP_002357391.1\|1542991_1543174_-	hypothetical protein	NA	NA	NA	NA
WP_010773973.1\|1543170_1543569_-\|holin	phage holin family protein	A0A097QQ04	Enterococcus_phage	6.6e-38	65.0
WP_015212190.1\|1543632_1545105_-\|plate	BppU family phage baseplate upper protein	D2IYX9	Enterococcus_phage	9.0e-32	52.8
WP_010830627.1\|1545104_1547372_-\|tail	phage tail protein	A0A1G5SAE0	Enterococcus_phage	7.7e-131	49.8
WP_002357387.1\|1547368_1548130_-\|tail	phage tail protein	A0A1D3SNM1	Enterococcus_phage	6.0e-64	46.3
WP_002381842.1\|1548129_1551399_-	tape measure protein	Q938K3	Temperate_phage	1.4e-69	44.8
WP_002357385.1\|1551391_1551961_-	hypothetical protein	Q5YA62	Bacillus_phage	4.7e-37	44.2
WP_002357384.1\|1551966_1552374_-	hypothetical protein	A0A1S5SEB3	Streptococcus_phage	1.1e-08	31.9
WP_002357383.1\|1552428_1552881_-	hypothetical protein	A0A0S2MYH7	Enterococcus_phage	4.7e-56	78.4
WP_010773974.1\|1552950_1553430_-	hypothetical protein	Q5YA64	Bacillus_phage	4.2e-47	64.8
WP_010830628.1\|1553429_1553828_-	hypothetical protein	Q5YA65	Bacillus_phage	2.4e-40	58.0
WP_002411221.1\|1553827_1554154_-\|capsid	phage capsid protein	Q5YA66	Bacillus_phage	2.3e-28	55.3
WP_002411222.1\|1554153_1554495_-	hypothetical protein	Q5YA67	Bacillus_phage	1.4e-36	61.9
WP_010784201.1\|1554488_1554893_-	hypothetical protein	Q5YA68	Bacillus_phage	1.7e-36	62.4
WP_015212191.1\|1554990_1555857_-	hypothetical protein	A0A1P8BKP7	Lactococcus_phage	5.2e-128	80.1
WP_010826285.1\|1555873_1556428_-	phage scaffolding protein	M1HNV6	Streptococcus_phage	7.8e-13	38.7
WP_002357372.1\|1556523_1556712_-	hypothetical protein	D2IYW5	Enterococcus_phage	1.3e-07	46.8
1556710:1556731	attL	NA	NA	NA	NA
WP_002411227.1\|1556763_1557921_-\|capsid	phage minor capsid protein	Q5YA73	Bacillus_phage	6.9e-136	60.3
WP_002357369.1\|1557920_1559420_-\|portal	phage portal protein	C5IUJ2	Streptococcus_phage	1.4e-104	43.7
WP_002357367.1\|1559435_1560725_-\|terminase	PBSX family phage terminase large subunit	A0A0B5CYJ6	Listeria_phage	5.3e-145	58.6
WP_002357366.1\|1560714_1561479_-	hypothetical protein	D6PSW8	Lactobacillus_phage	6.5e-58	62.0
WP_002414610.1\|1562860_1563124_-	hypothetical protein	A0A1B1P9Z3	Enterococcus_phage	2.9e-10	46.6
WP_002357362.1\|1563397_1563814_-	autolysin	D2IZL7	Enterococcus_phage	1.7e-68	99.3
WP_010731648.1\|1564236_1564407_-	hypothetical protein	D2IZL5	Enterococcus_phage	1.8e-24	92.9
WP_010731650.1\|1564874_1565024_-	hypothetical protein	NA	NA	NA	NA
WP_010731651.1\|1565020_1565356_-	hypothetical protein	D2IYU9	Enterococcus_phage	4.9e-34	87.7
WP_010731652.1\|1565356_1565737_-	hypothetical protein	D2IZL0	Enterococcus_phage	3.1e-37	67.2
WP_002406056.1\|1565720_1566293_-	hypothetical protein	A8ATD7	Listeria_phage	1.3e-23	33.1
WP_002406057.1\|1566305_1567250_-\|integrase	site-specific integrase	A8ATD6	Listeria_phage	1.8e-102	59.3
WP_002406058.1\|1567246_1567900_-	SAM-dependent DNA methyltransferase	A0A2D1GPI7	Lactobacillus_phage	1.4e-61	54.0
WP_002406059.1\|1567956_1568697_-	hypothetical protein	U4KJA1	Streptococcus_phage	8.7e-100	69.4
WP_010815126.1\|1568753_1568981_-	hypothetical protein	C9E2N4	Enterococcus_phage	2.3e-35	97.3
WP_002406061.1\|1569106_1569631_-	hypothetical protein	A0A0S2MYB8	Enterococcus_phage	4.0e-91	97.7
WP_010818749.1\|1569652_1569952_-	hypothetical protein	D2IZR4	Enterococcus_phage	1.0e-43	89.9
WP_002406063.1\|1569951_1570902_-	phage replisome organizer N-terminal domain-containing protein	C9E2N2	Enterococcus_phage	3.0e-68	51.3
WP_002369045.1\|1570902_1571583_-	hypothetical protein	C9E2N1	Enterococcus_phage	4.9e-126	98.7
WP_025189733.1\|1571579_1572518_-	DUF1351 domain-containing protein	C9E2N0	Enterococcus_phage	2.5e-120	94.5
WP_002357344.1\|1572502_1573180_-	ERF family protein	C9E2M9	Enterococcus_phage	3.7e-121	99.1
WP_002357343.1\|1573180_1573417_-	hypothetical protein	A0A0S2MYD6	Enterococcus_phage	3.1e-35	97.4
WP_002389151.1\|1573473_1573629_-	hypothetical protein	C9E2M7	Enterococcus_phage	1.1e-20	100.0
WP_002406302.1\|1573735_1573909_-	hypothetical protein	C9E2M5	Enterococcus_phage	6.8e-24	98.2
WP_002406301.1\|1573920_1574106_-	hypothetical protein	D2IZW5	Enterococcus_phage	1.1e-19	88.3
WP_002357336.1\|1574116_1574827_-	phage regulatory protein	D2IYT0	Enterococcus_phage	7.0e-123	95.7
WP_002357335.1\|1575095_1575311_-	hypothetical protein	NA	NA	NA	NA
WP_002357334.1\|1575375_1575600_+	hypothetical protein	NA	NA	NA	NA
WP_002357333.1\|1575593_1575764_-	hypothetical protein	NA	NA	NA	NA
WP_010830632.1\|1575783_1576080_-	hypothetical protein	NA	NA	NA	NA
WP_010773985.1\|1576066_1576330_-	hypothetical protein	E8ZDN3	Streptococcus_phage	2.3e-15	59.2
WP_049087928.1\|1576451_1577213_+	helix-turn-helix transcriptional regulator	Q6J1W4	Lactobacillus_phage	5.3e-52	47.0
WP_002357328.1\|1577294_1577885_+	DUF4352 domain-containing protein	A8ASM1	Listeria_phage	7.1e-20	46.2
WP_010822897.1\|1577949_1578117_+	hypothetical protein	NA	NA	NA	NA
WP_002357325.1\|1578178_1579312_+\|integrase	site-specific integrase	A0A1S5S7K9	Streptococcus_phage	5.8e-63	37.2
WP_002357324.1\|1579378_1580641_-\|tRNA	tyrosine--tRNA ligase	A0A1L2CUL7	Pectobacterium_phage	2.6e-80	42.0
1585201:1585222	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1618827 : 1627471

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002389224.1\|1618827_1619400_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.4e-25	35.1
WP_002365760.1\|1619396_1620428_-	phosphoribosylformylglycinamidine cyclo-ligase	M4QRQ6	Synechococcus_phage	3.1e-55	44.4
WP_002389355.1\|1620429_1621869_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.6e-49	33.1
WP_002365762.1\|1621844_1624064_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	7.5e-147	39.9
WP_002357272.1\|1624060_1624735_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_002365764.1\|1624735_1624987_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_002357270.1\|1625000_1625714_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3ELR0	Synechococcus_phage	4.3e-48	43.0
WP_002399033.1\|1625865_1626990_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_002365766.1\|1626982_1627471_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.4e-19	42.0

DBSCAN-SWA_6

1804850 : 1910945

119

Enterococcus_phage(81.58%)

tail,head,holin,integrase,protease,portal,capsid,terminase,transposase,tRNA

attL 1847179:1847205|attR 1891333:1891359

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002389120.1\|1804850_1805780_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_002389177.1\|1805780_1806527_-	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	3.6e-13	43.0
WP_002388976.1\|1806646_1807627_-	glycosyltransferase family 2 protein	A0A075B8F6	Enterobacteria_phage	2.4e-65	43.0
WP_080004755.1\|1807759_1808719_-	GDP-mannose 4,6-dehydratase	A0A1V0SKV4	Klosneuvirus	7.6e-48	36.6
WP_010818927.1\|1809040_1810465_-	O-antigen ligase family protein	NA	NA	NA	NA
WP_002389251.1\|1810464_1811595_-	glycosyltransferase	NA	NA	NA	NA
WP_002389220.1\|1811594_1813127_-	oligosaccharide flippase family protein	NA	NA	NA	NA
WP_002389014.1\|1813160_1814129_-	glycosyltransferase family 2 protein	A0A0F7L2F7	uncultured_marine_virus	4.7e-05	28.3
WP_002384311.1\|1814130_1815186_-	NAD-dependent epimerase/dehydratase family protein	A0A140G5S6	Enterobacteria_phage	3.7e-11	27.1
WP_015212212.1\|1815197_1815899_-	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_010818928.1\|1816146_1818159_-	hypothetical protein	U3PJ04	Lactobacillus_phage	2.6e-21	35.3
WP_002366946.1\|1818402_1819251_-	LicD family protein	NA	NA	NA	NA
WP_002356910.1\|1819266_1820025_-	glycosyltransferase	A0A1V0SAH6	Catovirus	3.9e-15	40.5
WP_015212213.1\|1820159_1821557_-	sugar transferase	NA	NA	NA	NA
WP_002378510.1\|1821662_1822964_-	EpaQ family protein	NA	NA	NA	NA
WP_002390225.1\|1822992_1824996_-	hypothetical protein	NA	NA	NA	NA
WP_002389162.1\|1824996_1827138_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_002388991.1\|1827149_1830293_-	glycosyltransferase	NA	NA	NA	NA
WP_002356901.1\|1830282_1831500_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.5e-08	24.0
WP_002356900.1\|1831512_1832307_-	ABC transporter permease	NA	NA	NA	NA
WP_002356899.1\|1832554_1832896_+	hypothetical protein	NA	NA	NA	NA
WP_002356898.1\|1832969_1833320_-	DUF2304 domain-containing protein	NA	NA	NA	NA
WP_002359897.1\|1833319_1834045_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_002356895.1\|1834103_1834946_-	dTDP-4-dehydrorhamnose reductase	A0A1D8EQE2	Escherichia_phage	4.2e-26	33.2
WP_002359895.1\|1835038_1836067_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	1.9e-68	41.9
WP_002356893.1\|1836091_1836664_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	2.4e-41	50.3
WP_002364387.1\|1836676_1837543_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	6.1e-105	63.9
WP_002384299.1\|1837665_1838379_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_002389137.1\|1838382_1839210_-	glycosyltransferase	NA	NA	NA	NA
WP_002359892.1\|1839209_1839998_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_002366956.1\|1840119_1841256_-	undecaprenyl/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase	NA	NA	NA	NA
WP_002383768.1\|1841366_1842275_-	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
WP_002389095.1\|1842290_1843055_-	type I methionyl aminopeptidase	NA	NA	NA	NA
WP_002356885.1\|1843229_1843673_+	flavodoxin	NA	NA	NA	NA
WP_002356884.1\|1843747_1844221_-	tryptophan-rich sensory protein	NA	NA	NA	NA
WP_002356883.1\|1844378_1844951_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_002389310.1\|1845201_1846440_+	aminopeptidase	NA	NA	NA	NA
WP_002356881.1\|1846699_1847080_+	PH domain-containing protein	A6N235	Microbacterium_phage	2.5e-10	33.0
1847179:1847205	attL	NA	NA	NA	NA
WP_002389108.1\|1847450_1848032_+	DUF4950 domain-containing protein	C9E2L5	Enterococcus_phage	4.2e-65	100.0
WP_007209349.1\|1848304_1849477_-\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	6.3e-121	88.4
WP_002389311.1\|1849729_1851232_+	glucosyltransferase domain-containing protein	C9E2L4	Enterococcus_phage	2.9e-275	100.0
WP_002369083.1\|1851295_1852588_-	peptidoglycan DD-metalloendopeptidase family protein	C9E2L3	Enterococcus_phage	1.3e-252	100.0
WP_002369082.1\|1852649_1853030_-	hypothetical protein	C9E2L2	Enterococcus_phage	1.1e-63	100.0
WP_002389028.1\|1853042_1854302_-	LysM peptidoglycan-binding domain-containing protein	C9E2L1	Enterococcus_phage	6.1e-239	100.0
WP_002381666.1\|1854306_1854510_-\|holin	phage holin	C9E2L0	Enterococcus_phage	1.2e-30	100.0
WP_041161918.1\|1854506_1854734_-	hypothetical protein	C9E2K9	Enterococcus_phage	9.9e-31	98.6
WP_002389099.1\|1854807_1856571_-	hypothetical protein	C9E2K8	Enterococcus_phage	4.7e-269	100.0
WP_002369077.1\|1856581_1856755_-	hypothetical protein	A0A097BYC2	Enterococcus_phage	3.1e-24	100.0
WP_002389090.1\|1856755_1858771_-\|tail	phage tail protein	C9E2K6	Enterococcus_phage	0.0e+00	100.0
WP_002389194.1\|1858787_1859717_-\|tail	phage tail family protein	C9E2K5	Enterococcus_phage	2.8e-180	100.0
WP_002388984.1\|1859717_1863125_-	tape measure protein	C9E2K4	Enterococcus_phage	0.0e+00	100.0
WP_002406573.1\|1863140_1863398_-	hypothetical protein	C9E2K3	Enterococcus_phage	7.0e-41	100.0
WP_002389328.1\|1863490_1863841_-	hypothetical protein	C9E2K2	Enterococcus_phage	1.5e-57	100.0
WP_002389144.1\|1863895_1864354_-	hypothetical protein	C9E2K1	Enterococcus_phage	1.1e-76	100.0
WP_002389268.1\|1864369_1864963_-\|tail	phage major tail protein, TP901-1 family	C9E2K0	Enterococcus_phage	1.6e-104	100.0
WP_002406570.1\|1864978_1865368_-	hypothetical protein	C9E2J9	Enterococcus_phage	2.3e-67	100.0
WP_002389229.1\|1865364_1865745_-	hypothetical protein	C9E2J8	Enterococcus_phage	1.8e-64	100.0
WP_002388983.1\|1865719_1866055_-	hypothetical protein	C9E2J7	Enterococcus_phage	1.4e-57	100.0
WP_002406569.1\|1866051_1866384_-\|head,tail	phage head-tail connector protein	C9E2J6	Enterococcus_phage	4.2e-54	100.0
WP_002389153.1\|1866457_1867471_-\|capsid	major capsid protein	C9E2J5	Enterococcus_phage	8.8e-188	100.0
WP_002389211.1\|1867493_1867835_-	hypothetical protein	C9E2J4	Enterococcus_phage	9.3e-57	100.0
WP_002389050.1\|1867847_1868489_-	DUF4355 domain-containing protein	C9E2J3	Enterococcus_phage	4.8e-107	100.0
WP_002389065.1\|1868618_1868897_-	hypothetical protein	C9E2J2	Enterococcus_phage	2.6e-49	100.0
WP_002406568.1\|1868989_1869259_-	hypothetical protein	C9E2J0	Enterococcus_phage	2.9e-45	100.0
WP_002389131.1\|1869259_1870198_-\|capsid	minor capsid protein	C9E2I9	Enterococcus_phage	1.5e-173	100.0
WP_002389154.1\|1870203_1871817_-\|portal	phage portal protein	C9E2I8	Enterococcus_phage	4.7e-308	100.0
WP_002389107.1\|1871821_1873276_-	DEAD/DEAH box helicase family protein	C9E2I7	Enterococcus_phage	1.6e-283	100.0
WP_002389091.1\|1873268_1874063_-\|terminase	small subunit of terminase	C9E2I6	Enterococcus_phage	3.0e-138	100.0
WP_002389113.1\|1874110_1875031_-	hypothetical protein	C9E2Q0	Enterococcus_phage	1.6e-167	100.0
WP_002389167.1\|1875075_1875264_-	hypothetical protein	C9E2P9	Enterococcus_phage	1.6e-26	100.0
WP_002389006.1\|1875400_1876009_-	hypothetical protein	C9E2P8	Enterococcus_phage	9.2e-116	100.0
WP_002389205.1\|1875995_1876517_-	ParB N-terminal domain-containing protein	C9E2P7	Enterococcus_phage	7.0e-96	100.0
WP_002389057.1\|1876571_1877021_-	hypothetical protein	C9E2P6	Enterococcus_phage	1.9e-73	100.0
WP_002389074.1\|1877484_1877901_-	autolysin	C9E2P5	Enterococcus_phage	4.4e-69	100.0
WP_002389002.1\|1878045_1878246_-	hypothetical protein	C9E2P3	Enterococcus_phage	1.6e-32	100.0
WP_002389222.1\|1878428_1878611_-	hypothetical protein	C9E2P1	Enterococcus_phage	5.9e-26	100.0
WP_002389003.1\|1878611_1879097_-	hypothetical protein	C9E2P0	Enterococcus_phage	8.2e-91	100.0
WP_002389116.1\|1879110_1879716_-	DUF3850 domain-containing protein	C9E2N9	Enterococcus_phage	9.5e-113	100.0
WP_002389257.1\|1879708_1879876_-	hypothetical protein	C9E2N8	Enterococcus_phage	5.6e-23	100.0
WP_002406561.1\|1879872_1880283_-	hypothetical protein	C9E2N7	Enterococcus_phage	7.0e-75	100.0
WP_016024806.1\|1880303_1880624_-	hypothetical protein	C9E2N6	Enterococcus_phage	1.5e-56	100.0
WP_002389342.1\|1880625_1881090_-	class I SAM-dependent methyltransferase	D2IYU6	Enterococcus_phage	6.6e-90	96.8
WP_002389214.1\|1881146_1881374_-	hypothetical protein	C9E2N4	Enterococcus_phage	6.0e-36	100.0
WP_002389023.1\|1881501_1882026_-	hypothetical protein	C9E2N3	Enterococcus_phage	3.6e-84	100.0
WP_002389312.1\|1882029_1882986_-	phage replisome organizer N-terminal domain-containing protein	C9E2N2	Enterococcus_phage	2.2e-148	100.0
WP_002389197.1\|1882990_1883671_-	hypothetical protein	C9E2N1	Enterococcus_phage	1.4e-128	100.0
WP_002410850.1\|1883667_1884606_-	DUF1351 domain-containing protein	C9E2N0	Enterococcus_phage	6.4e-124	100.0
WP_002389124.1\|1884590_1885268_-	ERF family protein	C9E2M9	Enterococcus_phage	5.6e-122	100.0
WP_002389004.1\|1885268_1885505_-	hypothetical protein	A0A0S2MYD6	Enterococcus_phage	6.2e-36	100.0
WP_002389151.1\|1885561_1885717_-	hypothetical protein	C9E2M7	Enterococcus_phage	1.1e-20	100.0
WP_002369040.1\|1885823_1885997_-	hypothetical protein	C9E2M5	Enterococcus_phage	2.3e-24	100.0
WP_002389279.1\|1886018_1886267_-	hypothetical protein	A0A0S2MYC6	Enterococcus_phage	2.1e-42	100.0
WP_002389123.1\|1886282_1887002_-	phage antirepressor KilAC domain-containing protein	C9E2M3	Enterococcus_phage	4.0e-134	100.0
WP_002389146.1\|1887083_1887317_-	DUF739 family protein	A0A0S2MYC3	Enterococcus_phage	7.8e-39	100.0
WP_002389244.1\|1887475_1888048_+	helix-turn-helix domain-containing protein	C9E2M1	Enterococcus_phage	1.1e-99	100.0
WP_002406281.1\|1888022_1888538_+	hypothetical protein	A0A0S2MYA6	Enterococcus_phage	1.0e-86	100.0
WP_002389038.1\|1888625_1889180_+	hypothetical protein	C9E2L9	Enterococcus_phage	8.7e-97	100.0
WP_002389192.1\|1889221_1889422_+	hypothetical protein	A0A0S2MYA2	Enterococcus_phage	7.4e-30	100.0
WP_002388998.1\|1889482_1890055_+	hypothetical protein	C9E2L7	Enterococcus_phage	1.3e-82	100.0
WP_002389338.1\|1890121_1891258_+\|integrase	site-specific integrase	C9E2L6	Enterococcus_phage	2.9e-211	100.0
WP_002389160.1\|1891451_1891973_-	nucleoside deaminase	NA	NA	NA	NA
1891333:1891359	attR	NA	NA	NA	NA
WP_002383772.1\|1892050_1892902_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002389263.1\|1892958_1893804_+	PhzF family phenazine biosynthesis protein	NA	NA	NA	NA
WP_002356871.1\|1893831_1894170_-	hypothetical protein	NA	NA	NA	NA
WP_002384290.1\|1894253_1894958_-	zinc metallopeptidase	NA	NA	NA	NA
WP_002387247.1\|1895156_1895510_+	YxeA family protein	NA	NA	NA	NA
WP_002356866.1\|1895547_1896552_-	nucleoid-associated protein	A0A090D855	Clostridium_phage	8.6e-10	22.3
WP_002388267.1\|1896679_1898146_-	PTS system trehalose-specific EIIBC component	NA	NA	NA	NA
WP_002356864.1\|1898358_1898739_+	VOC family protein	NA	NA	NA	NA
WP_002356863.1\|1898760_1899243_+	SRPBCC family protein	NA	NA	NA	NA
WP_002389175.1\|1899286_1900387_-	FUSC family protein	NA	NA	NA	NA
WP_002389127.1\|1900559_1902701_+	glycoside hydrolase family 92 protein	NA	NA	NA	NA
WP_002389323.1\|1902744_1904223_-	response regulator transcription factor	NA	NA	NA	NA
WP_002410847.1\|1904234_1905965_-	sensor histidine kinase	NA	NA	NA	NA
WP_002381610.1\|1905918_1906554_-	DUF624 domain-containing protein	NA	NA	NA	NA
WP_002369012.1\|1906624_1908091_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_002359877.1\|1908114_1909038_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_002389270.1\|1909049_1909988_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_002410846.1\|1910357_1910945_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_7

2268873 : 2278613

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002385686.1\|2268873_2271057_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	3.1e-286	66.8
WP_002365065.1\|2271089_2271686_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	2.3e-50	56.1
WP_002362328.1\|2271730_2272849_-	DNA polymerase IV	NA	NA	NA	NA
WP_002365066.1\|2272974_2273733_-	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_002356375.1\|2273716_2274379_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	6.7e-19	31.1
WP_002356373.1\|2274393_2275266_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	6.2e-81	57.6
WP_002356372.1\|2275377_2275725_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	8.1e-16	36.7
WP_002356371.1\|2275717_2276557_-	stage 0 sporulation family protein	NA	NA	NA	NA
WP_002384059.1\|2276673_2277624_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	6.2e-34	33.0
WP_002356367.1\|2277625_2277955_-	cyclic-di-AMP receptor	NA	NA	NA	NA
WP_002356366.1\|2277974_2278613_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.1e-54	53.8

DBSCAN-SWA_8

2376005 : 2411553

Enterococcus_phage(29.73%)

plate,tail,head,holin,integrase,protease,portal,capsid,terminase

attL 2370993:2371008|attR 2418584:2418599

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2370993:2371008	attL	NA	NA	NA	NA
WP_002355121.1\|2376005_2376206_-	cold-shock protein	Q9AZD3	Lactococcus_phage	5.3e-20	69.2
WP_080005969.1\|2376359_2376527_-	DNA repair protein	NA	NA	NA	NA
WP_002406268.1\|2376589_2377075_-	hypothetical protein	NA	NA	NA	NA
WP_010823164.1\|2377469_2378174_-	DUF3800 domain-containing protein	R4IBV1	Listeria_phage	1.5e-80	65.1
WP_015212238.1\|2378295_2378880_-	hypothetical protein	NA	NA	NA	NA
WP_015212239.1\|2379005_2380265_-	LysM peptidoglycan-binding domain-containing protein	D2J021	Enterococcus_phage	1.9e-219	93.6
WP_010711247.1\|2380269_2380473_-\|holin	phage holin	A0A0S2MYF6	Enterococcus_phage	2.6e-30	98.5
WP_002367247.1\|2380475_2380709_-	hemolysin XhlA family protein	D2J075	Enterococcus_phage	7.0e-24	70.2
WP_002374002.1\|2380742_2380898_-	XkdX family protein	A0A1D6Z281	Staphylococcus_phage	1.5e-06	46.0
WP_015212240.1\|2380899_2381220_-	hypothetical protein	NA	NA	NA	NA
WP_015212241.1\|2381230_2381719_-	hypothetical protein	A0A1L2K2Q1	Aeribacillus_phage	3.9e-08	34.2
WP_010823170.1\|2381718_2382036_-	hypothetical protein	NA	NA	NA	NA
WP_002411009.1\|2382028_2382346_-	hypothetical protein	NA	NA	NA	NA
WP_015212242.1\|2382342_2383248_-\|plate	phage baseplate upper protein	Q9AYV5	Lactococcus_phage	1.9e-11	25.7
WP_015212243.1\|2383262_2386007_-	peptidoglycan DD-metalloendopeptidase family protein	A0A1L2JXP5	Streptococcus_phage	9.0e-102	44.4
WP_015212244.1\|2386003_2386708_-	hypothetical protein	NA	NA	NA	NA
WP_015212245.1\|2386710_2389008_-\|tail	phage tail tape measure protein	V5UPR9	Enterococcus_phage	6.2e-72	51.4
WP_002395308.1\|2389199_2389655_-	hypothetical protein	A0A2H4J956	uncultured_Caudovirales_phage	1.7e-13	35.1
WP_041161937.1\|2389654_2390302_-\|tail	tail protein	A0A2H4JGN2	uncultured_Caudovirales_phage	5.9e-28	34.5
WP_002395306.1\|2390298_2390661_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_002398474.1\|2390650_2390989_-	hypothetical protein	A0A1B0T6B7	Bacillus_phage	6.4e-26	53.2
WP_002373974.1\|2390978_2391305_-\|head	phage head closure protein	A0A0N7IRA3	Lactobacillus_phage	1.2e-21	54.4
WP_025189140.1\|2391282_2391573_-\|head,tail	phage gp6-like head-tail connector protein	A0A1B1P7M9	Bacillus_phage	1.1e-21	60.5
WP_015212247.1\|2391565_2392921_-\|capsid	phage major capsid protein	A0A1B2APY9	Phage_Wrath	4.4e-126	67.7
WP_015212248.1\|2392933_2393506_-\|head,protease	HK97 family phage prohead protease	A0A1B2APW1	Phage_Wrath	1.7e-63	63.3
WP_015212249.1\|2393477_2394704_-\|portal	phage portal protein	A0A2H4J9C7	uncultured_Caudovirales_phage	4.9e-148	66.5
WP_002393033.1\|2394722_2396450_-\|terminase	terminase large subunit	A0A2H4JDG5	uncultured_Caudovirales_phage	3.2e-254	70.4
WP_002393034.1\|2396446_2396899_-	hypothetical protein	A0A2H4JFK0	uncultured_Caudovirales_phage	4.2e-49	70.6
WP_002304435.1\|2397007_2397388_-	HNH endonuclease	A0A1B1P7N1	Bacillus_phage	4.7e-41	64.0
WP_010784244.1\|2397384_2397783_-	hypothetical protein	NA	NA	NA	NA
WP_015212250.1\|2398311_2398779_-	transcriptional regulator, ArpU family	D7RWH7	Brochothrix_phage	1.7e-08	27.8
WP_015212251.1\|2398896_2399469_-	hypothetical protein	A8ATD7	Listeria_phage	7.8e-24	33.1
WP_015212252.1\|2399481_2400426_-\|integrase	site-specific integrase	A8ATD6	Listeria_phage	9.0e-102	59.0
WP_002406058.1\|2400422_2401076_-	SAM-dependent DNA methyltransferase	A0A2D1GPI7	Lactobacillus_phage	1.4e-61	54.0
WP_002406059.1\|2401132_2401873_-	hypothetical protein	U4KJA1	Streptococcus_phage	8.7e-100	69.4
WP_002385650.1\|2401926_2402133_-	hypothetical protein	A0A1B1V001	Enterococcus_phage	7.4e-25	96.8
WP_002410885.1\|2402148_2402754_-	hypothetical protein	NA	NA	NA	NA
WP_002410883.1\|2402765_2403293_-	DUF1064 domain-containing protein	A0A1I9KKZ1	Lactobacillus_phage	6.1e-31	48.3
WP_002410882.1\|2403515_2404355_-	ATP-binding protein	U5PVD6	Bacillus_phage	3.5e-20	32.5
WP_002406165.1\|2404366_2405155_-	DnaD domain protein	A0A0N7IRA7	Lactobacillus_phage	1.3e-53	55.2
WP_015212255.1\|2405920_2406892_-	recombinase RecT	A0A1S5SAA8	Streptococcus_phage	4.4e-59	45.1
WP_002370012.1\|2406994_2407219_-	hypothetical protein	D2IZX4	Enterococcus_phage	4.9e-22	67.1
WP_002406162.1\|2407215_2407515_-	hypothetical protein	NA	NA	NA	NA
WP_002370016.1\|2407601_2408018_-	hypothetical protein	NA	NA	NA	NA
WP_002393055.1\|2408211_2408355_-	hypothetical protein	D2IZW3	Enterococcus_phage	3.4e-13	87.8
WP_002364354.1\|2408365_2408542_-	helix-turn-helix transcriptional regulator	D2IZW2	Enterococcus_phage	1.7e-14	65.5
WP_002406160.1\|2408862_2409195_+	helix-turn-helix transcriptional regulator	D2IZV9	Enterococcus_phage	1.8e-57	99.1
WP_002406159.1\|2409212_2409557_+	ImmA/IrrE family metallo-endopeptidase	A0A097QQ08	Enterococcus_phage	4.6e-56	93.9
WP_002406158.1\|2409626_2410076_+	hypothetical protein	NA	NA	NA	NA
WP_002406157.1\|2410185_2411553_+	recombinase family protein	D2IZV7	Enterococcus_phage	4.2e-257	98.7
2418584:2418599	attR	NA	NA	NA	NA

DBSCAN-SWA_9

2669559 : 2721348

unidentified_phage(10.0%)

holin,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002360751.1\|2669559_2670519_+\|transposase	IS30-like element IS1062 family transposase	H7BW61	unidentified_phage	6.3e-10	26.1
WP_002370135.1\|2670805_2671819_-	alpha/beta hydrolase	A0A0G2Y6Q1	Acanthamoeba_polyphaga_mimivirus	3.9e-10	22.6
WP_002389413.1\|2671984_2672530_+	cysteine hydrolase	NA	NA	NA	NA
WP_002365411.1\|2672735_2673419_-\|holin	antiholin-like protein LrgB	NA	NA	NA	NA
WP_002354829.1\|2673415_2673835_-\|holin	antiholin-like murein hydrolase modulator LrgA	NA	NA	NA	NA
WP_002354828.1\|2673986_2674715_-	LytTR family transcriptional regulator DNA-binding domain-containing protein	NA	NA	NA	NA
WP_002390682.1\|2674695_2676444_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	3.2e-60	28.4
WP_002354826.1\|2676556_2677375_-	membrane protein	NA	NA	NA	NA
WP_002354825.1\|2677387_2678059_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_002354824.1\|2678055_2678778_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	9.2e-22	33.7
WP_002386234.1\|2679139_2679538_-	OsmC family protein	NA	NA	NA	NA
WP_002354822.1\|2679738_2680008_+	30S ribosomal protein S14	NA	NA	NA	NA
WP_002354818.1\|2680117_2680267_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_002367488.1\|2680282_2681257_+	GTP-binding protein	NA	NA	NA	NA
WP_002383181.1\|2681290_2681413_+	putative metal homeostasis protein	NA	NA	NA	NA
WP_002389398.1\|2681433_2682969_+	zinc ABC transporter substrate-binding protein AdcA	NA	NA	NA	NA
WP_002389417.1\|2683026_2684001_-\|tRNA	tRNA-dihydrouridine synthase	NA	NA	NA	NA
WP_002389460.1\|2684188_2684959_-	ABC transporter permease	NA	NA	NA	NA
WP_002389474.1\|2684951_2685887_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	2.4e-22	29.4
WP_002389491.1\|2686144_2686564_+	PTS mannose transporter subunit IIA	NA	NA	NA	NA
WP_002354800.1\|2686576_2687068_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_002365419.1\|2687084_2687900_+	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
WP_002360964.1\|2687896_2688724_+	PTS system mannose/fructose/sorbose family transporter subunit IID	NA	NA	NA	NA
WP_002389450.1\|2691538_2692099_-	hypothetical protein	NA	NA	NA	NA
WP_002389486.1\|2692884_2694957_-	AIPR family protein	NA	NA	NA	NA
WP_002389446.1\|2694947_2695853_-	PD-(D/E)XK motif protein	NA	NA	NA	NA
WP_002389428.1\|2695852_2698444_-	Z1 domain-containing protein	NA	NA	NA	NA
WP_002389395.1\|2698436_2699888_-	ATP-binding protein	NA	NA	NA	NA
WP_002389497.1\|2699880_2701038_-	DNA cytosine methyltransferase	A0A0E3DF50	Bacillus_phage	7.8e-31	29.5
WP_002354786.1\|2702057_2702450_-	30S ribosomal protein S9	NA	NA	NA	NA
WP_002365424.1\|2702463_2702907_-	50S ribosomal protein L13	NA	NA	NA	NA
WP_002354782.1\|2703128_2703596_-	DNA starvation/stationary phase protection protein	C1KFH1	Lactobacillus_virus	1.0e-05	25.9
WP_002389476.1\|2703723_2704443_-	DUF5105 domain-containing protein	NA	NA	NA	NA
WP_002368499.1\|2704526_2706047_-	gluconokinase	NA	NA	NA	NA
WP_002389394.1\|2706155_2706848_+	prepilin peptidase	NA	NA	NA	NA
WP_002354777.1\|2706896_2710550_-	DNA-directed RNA polymerase subunit beta'	R4TQM7	Phaeocystis_globosa_virus	1.4e-65	24.8
WP_002389470.1\|2710716_2714331_-	DNA-directed RNA polymerase subunit beta	A0A1B1ISA9	uncultured_Mediterranean_phage	2.0e-48	24.5
WP_002360937.1\|2714701_2715043_-	type II toxin-antitoxin system PemK/MazF family toxin	A0A1S5SAB3	Streptococcus_phage	4.2e-17	42.5
WP_002367500.1\|2715042_2715273_-	hypothetical protein	NA	NA	NA	NA
WP_111997057.1\|2715327_2715507_-	hypothetical protein	NA	NA	NA	NA
WP_002354768.1\|2715686_2715902_-	DNA-binding protein	NA	NA	NA	NA
WP_002389493.1\|2716040_2717033_+	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_015212268.1\|2717296_2717935_-	lytic polysaccharide monooxygenase	NA	NA	NA	NA
WP_015212269.1\|2718620_2720237_+	phosphatase PAP2/LCP family protein	NA	NA	NA	NA
WP_002411240.1\|2720565_2720715_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_073340360.1\|2720833_2720974_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_002381035.1\|2721204_2721348_+\|holin	putative holin-like toxin	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_019770

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection