CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_018828	Bordetella parapertussis Bpp5, complete genome	9 crisprs	csa3,DEDDh,cas3,DinG	7	3	6	3
NC_018830	Bordetella parapertussis Bpp5 plasmid BPP5P1, complete sequence	0 crisprs	NA	0	0	0	0

1. NC_018828

CRISPR-Cas detection and classification

Crispr_ID: NC_018828_1

• CRISPR_ID: NC_018828_1
• CRISPR_location: 473727-473826
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_018828_1

Consensus_repeat	Method
GCCTGTCCCTGCCGGGGAGCGACA	CRISPRCasFinder

spacers of NC_018828_1

>1.1|473751|52|NC_018828|CRISPRCasFinder
TCTGCGGCCAGGGAGCCTGTCCCCGCCGGGGAGCGACATCTGCGGCCAGGGT

CRISPR arrays and Neighbor proteins around NC_018828_1

CRISPR arrays

The CRISPR arrays of NC_018828_1

>merge|NC_018828|1|473727-473826|CRISPRCasFinder
GCCTGTCCCTGCCGGGGAGCGACATCTGCGGCCAGGGAGCCTGTCCCCGCCGGGGAGCGACATCTGCGGCCAGGGTGCCTGTCCCTGGCGGGGAGCGACA

>NC_018828|1|1|473727-473826|CRISPRCasFinder
GCCTGTCCCTGCCGGGGAGCGACA	TCTGCGGCCAGGGAGCCTGTCCCCGCCGGGGAGCGACATCTGCGGCCAGGGT
GCCTGTCCCTGGCGGGGAGCGACA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018828.1|WP_003807769.1|483026_484259_+|dehydratase/racemase	unknown	unknown	gnl|CDD|211976
NC_018828.1|WP_003807739.1|454962_456153_+|voltage-gated-potassium-channel-protein	unknown	unknown	gnl|CDD|236711
NC_018828.1|WP_033446678.1|479124_480114_+|oxidoreductase	unknown	unknown	gnl|CDD|176248
NC_018828.1|WP_015038821.1|462363_473037_+|autotransporter-BatB	unknown	unknown	gnl|CDD|185219
NC_018828.1|WP_015038820.1|461882_462065_+|DUF3596-domain-containing-protein	unknown	unknown	gnl|CDD|371934
NC_018828.1|WP_003807753.1|474134_475112_+|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270234
NC_018828.1|WP_003807771.1|484322_485288_+|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270234
NC_018828.1|WP_015038817.1|456160_456556_-|RidA-family-protein	unknown	unknown	gnl|CDD|223329
NC_018828.1|WP_015038825.1|480205_481459_+|CoA-transferase	unknown	unknown	gnl|CDD|367110
NC_018828.1|WP_003807755.1|476384_477125_+|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NC_018828.1|WP_010925819.1|482553_483030_+|MaoC-family-dehydratase	unknown	unknown	gnl|CDD|239535
NC_018828.1|WP_033457305.1|473088_473670_+|ureidoglycolate-hydrolase	unknown	unknown	gnl|CDD|380432
NC_018828.1|WP_003807759.1|477957_478293_+|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl|CDD|223672
NC_018828.1|WP_015038819.1|460286_460946_-|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|319787
NC_018828.1|WP_015038826.1|485274_486261_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176161
NC_018828.1|WP_015038818.1|457689_458562_+|hypothetical-protein	unknown	unknown	gnl|CDD|259799
NC_018828.1|WP_015038823.1|477148_477913_+|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|119339
NC_018828.1|WP_003807743.1|458637_458973_-|YegP-family-protein	unknown	unknown	gnl|CDD|377831
NC_018828.1|WP_003807744.1|459113_460259_-|DSD1-family-PLP-dependent-enzyme	unknown	unknown	gnl|CDD|143487
NC_018828.1|WP_003807741.1|456725_457427_+|glutathione-S-transferase	unknown	unknown	gnl|CDD|373097

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018828.1|WP_003807769.1|483026_484259_+|dehydratase/racemase	gnl|CDD|211976	TIGR04253, mesacon_CoA_iso, mesaconyl-CoA isomerase. Members of this protein family belong by homology to the family of CoA transferases. However, the characterized member from Chloroflexus aurantiacus appears to perform an intramolecular transfer, making it an isomerase. The enzyme converts mesaconyl-C1-CoA to mesaconyl-C4-CoA as part of the bicyclic 3-hydroxyproprionate pathway for carbon fixation.	1.41186e-122
NC_018828.1|WP_003807739.1|454962_456153_+|voltage-gated-potassium-channel-protein	gnl|CDD|236711	PRK10537, PRK10537, voltage-gated potassium channel protein.	0
NC_018828.1|WP_033446678.1|479124_480114_+|oxidoreductase	gnl|CDD|176248	cd08288, MDR_yhdh, Yhdh putative quinone oxidoreductases. Yhdh putative quinone oxidoreductases (QOR). QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	0
NC_018828.1|WP_015038821.1|462363_473037_+|autotransporter-BatB	gnl|CDD|185219	PRK15319, PRK15319, fibronectin-binding autotransporter adhesin ShdA.	2.28385e-37
NC_018828.1|WP_015038820.1|461882_462065_+|DUF3596-domain-containing-protein	gnl|CDD|371934	pfam12167, Arm-DNA-bind_2, Arm DNA-binding domain. This domain is found at the N-terminus of various phage integrases. The domain binds to DNA.	6.38453e-09
NC_018828.1|WP_003807753.1|474134_475112_+|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl|CDD|270234	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) proteins present in a number of bacterial species, but mainly in proteobacteria. In eubacteria, at least three families of periplasmic binding-protein dependent transporters are known: the ATP-binding cassette (ABC) transporters, the tripartite ATP-independent periplasmic transporters, and the tripartite tricarboxylate transporters (TTT). Bug proteins are the PBP components of the TTT. Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	8.51184e-99
NC_018828.1|WP_003807771.1|484322_485288_+|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl|CDD|270234	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) proteins present in a number of bacterial species, but mainly in proteobacteria. In eubacteria, at least three families of periplasmic binding-protein dependent transporters are known: the ATP-binding cassette (ABC) transporters, the tripartite ATP-independent periplasmic transporters, and the tripartite tricarboxylate transporters (TTT). Bug proteins are the PBP components of the TTT. Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	1.0952e-123
NC_018828.1|WP_015038817.1|456160_456556_-|RidA-family-protein	gnl|CDD|223329	COG0251, TdcF, Putative translation initiation inhibitor, yjgF family [Translation, ribosomal structure and biogenesis].	1.37572e-36
NC_018828.1|WP_015038825.1|480205_481459_+|CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	6.9508e-143
NC_018828.1|WP_003807755.1|476384_477125_+|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	4.17717e-46
NC_018828.1|WP_010925819.1|482553_483030_+|MaoC-family-dehydratase	gnl|CDD|239535	cd03451, FkbR2, FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2 has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. The function of FkbR2 is unknown.	1.58721e-71
NC_018828.1|WP_033457305.1|473088_473670_+|ureidoglycolate-hydrolase	gnl|CDD|380432	cd20298, cupin_UAH, ureidoglycolate amidohydrolase (UAH) and related proteins, cupin domain. This family includes the cupin-fold protein, ureidoglycolate hydrolase (AllA; EC 3.5.3.19), which is involved in the breakdown of allantoin under aerobic conditions. Allantoin is the key intermediate of nitrogen fixation in bacteria, and its degradation occurs in several steps. AllA is involved in the third step of this pathway which consists of hydrolysis of (S)-ureidoglycolate to yield glyoxylate, ammonia, and CO2. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.14658e-15
NC_018828.1|WP_003807759.1|477957_478293_+|carboxymuconolactone-decarboxylase-family-protein	gnl|CDD|223672	COG0599, COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown].	1.70453e-16
NC_018828.1|WP_015038819.1|460286_460946_-|HAD-IA-family-hydrolase	gnl|CDD|319787	cd02588, HAD_L2-DEX, L-2-haloacid dehalogenase. L-2-Haloacid dehalogenase catalyzes the hydrolytic dehalogenation of L-2-haloacids to produce the corresponding D-2-hydroxyacids with an inversion of the C2-configuration. 2-haloacid dehalogenases are of interest for their potential to degrade recalcitrant halogenated environmental pollutants and their use in the synthesis of industrial chemicals. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.19984e-33
NC_018828.1|WP_015038826.1|485274_486261_-|LysR-family-transcriptional-regulator	gnl|CDD|176161	cd08472, PBP2_CrgA_like_3, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 3. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.83935e-93
NC_018828.1|WP_015038818.1|457689_458562_+|hypothetical-protein	gnl|CDD|259799	cd03401, SPFH_prohibitin, Prohibitin family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model characterizes proteins similar to prohibitin (a lipid raft-associated integral membrane protein). Individual proteins of the SPFH (band 7) domain superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. These microdomains, in addition to being stable scaffolds, may also be dynamic units with their own regulatory functions. Prohibitin is a mitochondrial inner-membrane protein which may act as a chaperone for the stabilization of mitochondrial proteins. Human prohibitin forms a hetero-oligomeric complex with Bap-37 (prohibitin 2, an SPFH domain carrying homolog). This complex may protect non-assembled membrane proteins against proteolysis by the m-AAA protease. Prohibitin and Bap-37 yeast homologs have been implicated in yeast longevity and in the maintenance of mitochondrial morphology.	1.71821e-48
NC_018828.1|WP_015038823.1|477148_477913_+|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|119339	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.	5.39246e-58
NC_018828.1|WP_003807743.1|458637_458973_-|YegP-family-protein	gnl|CDD|377831	pfam07411, DUF1508, Domain of unknown function (DUF1508). This family represents a series of bacterial domains of unknown function of around 50 residues in length. Members of this family are often found as tandem repeats and in some cases represent the whole protein. All member proteins are described as being hypothetical.	1.7869e-18
NC_018828.1|WP_003807744.1|459113_460259_-|DSD1-family-PLP-dependent-enzyme	gnl|CDD|143487	cd06812, PLPDE_III_DSD_D-TA_like_1, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes Similar to D-Serine Dehydratase and D-Threonine Aldolase, Unknown Group 1. This subfamily is composed of uncharacterized bacterial proteins with similarity to eukaryotic D-serine dehydratases (DSD) and D-threonine aldolases (D-TA). DSD catalyzes the dehydration of D-serine to aminoacrylate, which is rapidly hydrolyzed to pyruvate and ammonia. D-TA reversibly catalyzes the aldol cleavage of D-threonine into glycine and acetaldehyde, and the synthesis of D-threonine from glycine and acetaldehyde. DSD and D-TA are fold type III PLP-dependent enzymes, similar to bacterial alanine racemase (AR), which contains an N-terminal PLP-binding TIM barrel domain and a C-terminal beta-sandwich domain. AR exists as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Based on their similarity to AR, it is possible members of this family also form dimers in solution.	0
NC_018828.1|WP_003807741.1|456725_457427_+|glutathione-S-transferase	gnl|CDD|373097	pfam14497, GST_C_3, Glutathione S-transferase, C-terminal domain. This domain is closely related to pfam00043.	2.46322e-31

Protein sequences

>NC_018828.1|WP_033457305.1|473088_473670_+|ureidoglycolate-hydrolase
MPTTTPALRPQVLTETAFAPYGWMLGKPLPAGGDVPRFSNPATDFWQEHVFDTGVGAGRETEVLWVNYRVSQPGFDTLEKHLLTQQAIVPLTGAIVQIVARSAFDGSPDLASLAAFVVPPGQGICMRPGCWHATRISGGEVTCLMLTRRSTTLDLVRHLHGEPARESEIVAIVPHGLDLPARPTTEGPSPHGR
>NC_018828.1|WP_015038821.1|462363_473037_+|autotransporter-BatB
MPQRSQPFNSYTGHSGVRGHGVAPTVLVLALGFHGTAAWANCQTAGSAVTCDASSPNPYTGTVGSGASSGNLTITVGPGARIESGNAHAISVGTGNTISLDGNAQVSNSVTTGGPGNYNAGLNTIEFEHTNTLMIGADARVAAEGTDPAAHAIAFTGRTNVVTNYGTVSSASGAAIWNQLEDNYVNNTIYNYGVIETTANGGNAVVIGSATGNGATDRGMSLYNYAGGRIVGNVVLGEGDDTVRLEAGSTLTGSLDGGAAGTDVLYLEGTSGSGELTQDISNFNEINKIVNGSTWTLAGSLGANSSGKATVVNAYNGELIVTGDNSAATAGSMMTVWAGARLQVNTTSAMAAIQSNGSSVAAFSQQTDGTYAGVLSGSGNFAKEGAGSLTLTGVNTYTGTLQLKEGKVIVSAAENLGGANSMLEFDGGTLNTTSDMTSVRRASIAAGGGTFEVAGGTTLNWTGRVVGNGTLVKEGAGTLALSGFNAHGGTVVNAGTVQISNDYGLGNGALTLNNSRLASTADIYTEAAATVNGNGTFDTANGTTLQWMGDIGGAGALVKTGAGTLLLGGDSLYAGGTVVNAGTVQVFKDASLGGGALTLNNASLASLGSFSTARAATLTGNGTFDTATGTTLGWTGDIGGAGALVKTGQGTLVLGGDNQYAGGTTVNAGAVQVSRDANLGAAAGAVALNDARLASTGTFSTARAATLTGNGTFDAATGTTLEWTGDIGGAGALVKTGQGTLVLGGDNQYGGGTTVNAGTVQVARDANLGVAAGTVALNGGTLAASASFSSARGVTIGAGNGAMSVASGASLDWQGLIDGTGALIKEGAGTLVLGNDNQYAAGTVVNAGTVQVARDANLGAAAGAVALNGGTLAASAGFSSARGVTIGAGNGAMSVASGASLDWQGLIDGTGALIKEGAGTLVLGNDNQYAAGTVVNAGTVQVSRDANLGAAAGTVALNDARLASTGTFSTARAATLTGNGTFDTADGTALGWTGDIGGAGALVKEGLGTLVLDGDNQYGGGTTVNAGTVQVARDANLGAAGGAVRLQGATLASTGSFATARAATLNNAGQIDTAQGTTLTWNGAIGGKGELRKQGAGTLVLGGANTYQGDTRVEAGTLQVSADANLGQGAVHLHDSRLATTGTFATSRRLELTGRGTVQAAAAATLDWRGTVAGAGTLVKEGAGTLVLGGDNQYGGGTEVNAGTLQVSRATNLGPGALALENAALATTASFTATQAATLTGNAAIDTAAGTTLGWEGAIGGTGSLHKKGEGKLVLVKDNQYGGGTTVNAGTVQVSRDANLGSGQSAVTLDGGALAVSAGFSSGREIVVGAGHGALSVAGGHTLQWQGQVGGAGALTKTGDGTLVLEHDNTHAGGTRVTGGVLRVSRDENLGEAHGMLTLDGGTLSTTAGFASRRNATVGNGGGRIVVADSATLDLQGDVAGAGRLVKEGAGTLALGGTNTYAGGTVVEAGTLRVARDANLGGGALTLNNSRLHATAGFATGRDATLTGRASIDTDNRATLQWRGTVDGAGRLVKQGLGTLVLDGDNRYAGGTEVNAGTLQVARDANLGAGDVALNGSRLAATASFATARTATLSGAAAIDTADGVTLDWNGLLDGDGALVKQGNGTLALAAANRYGGGTIVKAGAVRIARDANLGRAGTGVTLDGGALATTADLATGRAATLGAAHGTLEVAAGTRLDWNGAIGGAGALVKTGQGTLVLGGDNQYAGGTTVNAGAVQVSRDANLGAAAGAVALNDARLASTGTFSTARAATLTGNGTFDAATGTTLEWTGDIGGAGALVKTGQGTLVLGGDNQYGGGTEVNAGTLQVSRATNLGPGALALENAALATTASFTATQAATLTGNAAIDTAAGTTLGWEGAIGGTGSLHKKGEGKLVLVKDNQYGGGTTVNAGTVQVSRDANLGSGQSAVTLDGGALAVSAGFSSGREIVVGAGHGALSVAGGHTLQWQGQVGGAGALTKTGDGTLVLEHDNTHAGGTRVTGGVLRVSRDENLGEAHGMLTLDGGTLSTTAGFASRRNATVGNGGGRIVVADSATLDLQGDVAGAGRLVKEGAGTLALGGTNTYAGGTVVEAGTLRVARDANLGGGALTLNNSRLHATAGFATGRDATLTGRASIDTDNRATLQWRGTVDGAGRLVKQGLGTLVLDGDNRYAGGTEVNAGTLQVARDANLGAGDVALNGSRLAATASFATARTATLSGAAAIDTADGVTLDWNGLLDGDGALVKQGNGTLALAAANRYGGGTIVKAGAVRIARDANLGRAGTGVTLDGGALATTADLATGRAATLGAAHGTLEVAAGTRLDWNGAIGGAGALVKTGQGTLVLGGDNQYAGGTTVNAGAVQVSRDANLGAAAGAVALNDARLASTGTFSTARAATLTGNGTFDAATGTTLEWTGDIGGAGALVKTGQGTLVLGGDNQYGGGTTVNAGTVQVSRDTNLGSGQSAVTLDGGALAVSAGFSSGREIVVGAGHGALSVAGGHTLQWQGQVGGAGALTKTGDGTLVLEHDNTHAGGTRVTGGVLRVSRDENLGEAHGMLTLDGGTLSTTAGFASRRNATVGNGGGRIVVADSATLDLQGDVAGAGRLVKEGAGTLALGGTNTYAGGTVVEAGTLRVARDANLGGGALTLNNSRLHATAGFATGRDATLTGRASIDTDNRATLQWRGTVDGAGRLVKQGLGTLVLDGDNRYAGGTEVNAGTLQVARDANLGAGDVALNGSRLAATASFATARTATLSGAAAIDTADGVTLDWNGLLDGDGALVKQGNGTLALAAANRYGGGTIVKAGAVRIARDANLGRAGTGVTLDGGALATTADLATGRAATLGAAHGTLEVAAGTRLDWNGAIGGAGALVKTGAGTLALNHDNQHAGGTLVHGGTLRIARDANLGAAGTAVTLDGGTLATTASLALDRALRVGARNGVLQPDAGTTLDWRGVVAGAGKLTKAGPGMLVLSADNRHGGGTAVTGGTLQVSRDAHLGAAAGALTLDGGTLLSTASFASARAATLDAAGGTFVTRDGTRLDWDGAIGGAGGLVKEGAGELRLGNANTYQGPTRIAAGRLAVNGSIASPVTVEQAGVLGGTGRIVGDVANRGVVAPGNLIGALTVAGNYAGTGGSLEVEAVLGGDAAPADRLVLDGGAASGVTPVVVKPQGGVGGLTLRGIPVVVAQGGATTAPGAFRLAQPLVAGVYEYQLLRGAGDGAAAQAQDWYLRTSRVERDKAGRIVKVVPFYRPEVALYAGTPMLMRMTGTEMLGSYRERAGQTGAVSPEAGATAARGGWARTFGRRFERSAGGEAAPSFDGHLAGAQLGADLYARSSGTRHTDAFGVFGGYATVRGDVHGLARGEIQAVGTSTLRATQLGAYWTHTGPGGWYIDTVLAGTRYRQQTKSSAQVGAVSRGWGMTASVEAGYPWQLNPRWRIEPQAQVVYQQLGIANGADRVSTVSYKTPDALTARLGTRLSGQYAYGKAQLRPFMGVSLLHDFTGADTVTFAGAHGVRASRQNTAVDLKAGVDTQLGKSVGLWGQVGYGKSVGSGDGSDRGWSANLGLRVAY
>NC_018828.1|WP_015038820.1|461882_462065_+|DUF3596-domain-containing-protein
MSGKFEGVRPASESSIEISFVYQGKTCVRRLRMKPTAANLKRAAEQRAAIVEAIARGEQA
>NC_018828.1|WP_015038819.1|460286_460946_-|HAD-IA-family-hydrolase
MSIATPTGYPRAILFDLLTGLLDSWTAWNAAAGSEPAGRAWRAEYLRLAYGCGRYVPYGQLVRDAARATGLPDGAPAALEANWHELPVWDDARSLLRALRPHCKLAVVTNCSRDLGHQAAGLLGVDWDAVVTAEEAGFYKPDPRPYRMALQALQVPAGDAAFVAGSGHDLFGTAAVGLRTCWHNRLGLARPQGAPEPELQSATLAAALPWLQAFRPAVR
>NC_018828.1|WP_003807744.1|459113_460259_-|DSD1-family-PLP-dependent-enzyme
MTTTHAHPLDTLDTPAAIVDVARMQHNIARMQDRMNGLGVSLRPHVKTSKCTPVALAQLAAGARGVTVSTLKEAEQFFAAGIADILYAVGMAEHRLPAALALRRRGCDLKIITDNAESARTIADFGRAHDEVFEVWIEIDTDGHRSGIKPEEAALLAVGAALHEGGMRLGGVMTHAGSSYDLDTPEALAAMAEQERAGCVRAAERLRAAGLPCPVVSVGSTPTALSAAQLQGVTEVRAGVYVFFDLVMHNIGVCRVDELALSVLATVIGHQADKGWVIVDAGWMAMSRDRGTQKQKQDFGYGQVCTADGAPLAGYTLIGANQEHGIMAGGPAGEDVTTRFPVGMRLRILPNHACATGAQFPQYHALEADGGLQAWERAHGW
>NC_018828.1|WP_003807743.1|458637_458973_-|YegP-family-protein
MSGYFVLKASGTQYMFNLHAGNHEIILTSERYTSKASAQDGIASVQKNAPDDARYQRLTAKDGSPYFSLTATNGQSIGRSEMYKTTQARDNGIASVKSNAPGAPTKDQTQA
>NC_018828.1|WP_015038818.1|457689_458562_+|hypothetical-protein
MIPRNAKLAAGAGAGAGVLFVLILMLAFSSWFQVDQGERGVVLRNGKLVRVSEPGLDFKTPFIDSVSTVSVRDHTFIFENLEAYSYDQQPATLRVSVTYRVPAEHVAELYAEYGTISNLQMRVLERKTPDAVKNVFGRYTAVRAIQERQKLGVDVNAAVLSAMDGAPVQIVGVQVEEVGFSKAYEHSIEQRMLAQVQIETTRQQKETAMITAEIQVVKAKAEADARRQQFTAEADGIRLRGEAEAASIRAKAEALAANTNLVSLNAVEKWDGVLPATQVPGAALPFIGIK
>NC_018828.1|WP_003807741.1|456725_457427_+|glutathione-S-transferase
MAYDLWYWDGIPGRGEFVRLALEAGKIPYRDRAREPGEDMLDDMRRRRDTPPFAPPYLVADGMTIAQTANILLFLGVEHGLAPPDRAGRLWVNQLQLTIADLTAEAHDVHHPVAAGLYYEDQQDVALRRAADFRETRMPKFMQYFEQALDRPGGWLTDMGRWSYADLSLYHVVEGLLHAFPRRMRTLVHRYPRLMALHARVAELPELRGYLASDRRLPFGDGIFRHYPELDGA
>NC_018828.1|WP_015038817.1|456160_456556_-|RidA-family-protein
MPASTAPARYLAPDSLARPGGHYSHACVANGMVYVSGQLPIGPDGTKLADAPFEAQARQVLDNVAAALAAAGSGIDRLVQVRVYVDSVENWPAFDAIYAEWAGAARPARAVVPTGPLHYGFKVEVEAVALA
>NC_018828.1|WP_003807739.1|454962_456153_+|voltage-gated-potassium-channel-protein
MIRLRNFLRRIGRYFPPNWWLAALVAIDGYLFVRPVLGRAVDYPMDYWLSFDSWRDAMDAVGLLQIPRVILGAGLLLMAAGLVLKARIAWAFSLVLLGAIGVVAGWDGGHGLLLAYTGVLIAALVCFWRRFDRASLAAGSLFAVISITSLLIYAVFGTLYLGAEFSPKVESPATAFYFSIVSMSTVGYGDITPQTTAARLFAASIIILGITVFATSISAIAGPVIGGNLKRLVRGRISHAMRKHHIIIAGATPLAQSVYAGMRERGNNVTVVVAPGIAHNYPEDADLVTGDPSNTAVLAEAGAAHARYVLALRDDDADNAFIVLAAKEVAGPDTKTVAVANTAMHLAKIRRVQPDMVFSLQLLGAELLARTLSGETIDNALITDLFFTKATPSSAA
>NC_018828.1|WP_003807753.1|474134_475112_+|tripartite-tricarboxylate-transporter-substrate-binding-protein
MYRIVSALAVSVTCLAGMGAAQADQGAAAYPDKPIKIVIPYSAGGGTDQFMRIVSERASRVLGQPITILNKPGGSTVIGVNAVIGAAPDGYTLLVSTNTSYTLIPYVMSPPPYAPEKSLDYVATLGQTSMVLTANKTMPSDLKTVLDSARQSPGRYTYATYGVGSSTHLAGEVFMNDTGVEFRHIPYKGVEAVTALAGNQVDLMIDGINAAGTMLDAGKTQALVVLQRTRSQFLPDTPTLVEAGYPEAAENVISYVMAAPKGTPAAVIDKLQKSFAEALRDPGVLAQAKAMRTEAAFKGPAQTQAFVDSQSALFKDIVAKKNIKF
>NC_018828.1|WP_003807755.1|476384_477125_+|IclR-family-transcriptional-regulator
MSNPLNRYHHILHAIAGRPGGLSLADLAAATGLPRSTTHRMATTLREIDYLGQDDASGNFVLGDGLIGLMRSSLAQDSKLALFDPALNFVVGRLEETAFCARLWNDEVDLVQAVTPTRKDQLYIYPGVGGRPLDKCSSSKAILAYLDPARIQALLEPLASSTPGLRVDTLMQELDQVHRQGFAICDGEIDEGVLSVACPVMSGPARGLYSIGVVGPAARLKSHDLQEIVEVLHSAADLAAAELLNS
>NC_018828.1|WP_015038823.1|477148_477913_+|enoyl-CoA-hydratase/isomerase-family-protein
MKEIISLEKTGAVATVTIDRGGKRNALSQEMVLRLTDIALQLQQDTSVACIVLSGNQNEFSAGIDLGDATRWSLDDKTQLERRAIALRGTRLCKAWEDLPQITIAAVEGMNVGGGIALTLACDWRVMGKSAFLFVPEVQIGIPLGWQTIPRLVNLVGPARAKQIVLLGEKMSADTALEWGVADFVVADGAACAHAQDLAARIGKMPELAVRMSKQSINAYANALNHLGSHMDVDQAMLCGQTQDAVAVRNRYAR
>NC_018828.1|WP_003807759.1|477957_478293_+|carboxymuconolactone-decarboxylase-family-protein
MLDWNQYRSELMTRIGEIAKASPETVKGYQQLSAAGKQTNQLDAKTRELIALAVAVTTRCDGCIAVHAKAATDNGATKGEIAEALGVAVALNAGAALVYSARVMDAVDAAQ
>NC_018828.1|WP_033446678.1|479124_480114_+|oxidoreductase
MFDALLLTQNDDRAIVAQRARLDEAQLPDGDVLVDIAWSTVNYKDALAITGRIPIVRQFPMVPGIDFAGTVLESHDSRYRAGDAVLLNGWGLGEAHWGGLARKARVKADWLVPMPGGMDARRAMAIGTAGYTAMLCVMALQRAGVSPEAGPVLVTGANGGVGTIAISLLARLGFEVHASTGRLNEADYLKQLGATELIDRATLNQPGKPLQKERWAAAVDSVGSHTLANVCASIRYGGTVAACGLAQGMDFPATVAPFILRGVTLAGIDSVYAPFARRAEAWGRLASELPAEITDANTRAITLDEVVDLAPRLLAGQVRGRVVVDVGAG
>NC_018828.1|WP_015038825.1|480205_481459_+|CoA-transferase
MQSFYQEPAVAADLKEAPHPPKALSGLRVLDIATFLAAPFCGTIMADFGADVIKIEQPKGGDSLRKFGTPSPCGDTYMWMSEARNKRFVTLDLRTPEGAALFKELVRESDVVLENFRPGTLEKWGLGYDVLSELNPGLILLRVSAYGQDGPKREEPGFARIAHAFGGLAHLAGEPDGPPVVPGSTSLADYISGLWGAIGVLTALQARNHTGLGQVVDIGLYESVFRLLDEIAPVYAATGFVRRRLGADVPNVAPHSHYQTRCGQWVAIACSNDRMFERLASAMGKPELAGDARFATAAARAESRPAINAQVAAWSARFDLQALLDLCRDEGVPCSKVYSIEDIFQDEQYRARGNLMEVDDPRIGKTVLPAPVPRLSGTPARFLRAGGALGQDNAGVFEELLGVCGERLAALRQAGVV
>NC_018828.1|WP_010925819.1|482553_483030_+|MaoC-family-dehydratase
MLLARGRLLEDFKTGDQYAHWPGRTITEADNIQFSLLTMNRHPAHCDHHYASQTEFGKPLVNSGLTLAIVLGMSVDDISANAVANLGWQEIELLAPVHPGDTVYARSQVLSVRESKSRPGQGVVTVRTEGVRADGVVFMRFVRSCLVPSRASLAGARQ
>NC_018828.1|WP_003807769.1|483026_484259_+|dehydratase/racemase
MNLDFLKGVRVIESSAFIAAPLAGLTLAQFGAEVIRLDMTGGGIDYERMPRMPDGTSLYWTGLNKQKRSVALDLRKPEGRDLARKLVCAPGPDAGILLTNIGVPWLSHAALAEGRPDVITCTIEGNADGSSAVDYTVNCATGYPHATGDGREPVNSPLPAWDACCGYQAAMAVVSAVLRRRQTGQGAELRLALSDVAFALMSHLGTLAQAELLGEDREPLGNHLYGAFGRDFVTRDGNRVMVAAISKGQWQSLVRTCGLAEAVAAIEARTGAKLAEEAQRFAHRDAIAAACEPWFRARTLAQAKTALDDGGVCWGLYQTATQMLARDGRAGSANPLFERIATAGAGEHWALGTPVREPRATRQPTQGASRLGQHTDQVLGELLGLSARQLSDLHAAGVVAGPSGDPRGAH
>NC_018828.1|WP_003807771.1|484322_485288_+|tripartite-tricarboxylate-transporter-substrate-binding-protein
MTLRFASLAAALCILAPQAHATQAYPDKPVRIIVPWTPGQATDVAARAAGEKLAAALGQPFIVENRAGAGGTIGATAVAKSEADGYTLLAGSSGSVTVNPLLMKSGFSPSDLEPAGLVAKVPYVLVTSSDFPAKTAQELIDLLRKSPEKYTFASSGNGSIGHLTAEVFMDSAGIKAQHIPYKGSAAALTDVLSGQVSFMWDSVASVAPHVKSGRARAYAVSSAQRSASMPDVPVLAEVSEIKGFDMVAWVGLMAPKGTPEDRLERINQALLESLRASDVAKQFVTLGIDPYPASRQEARKVLAAENQRVSEMIQRLGITPQ
>NC_018828.1|WP_015038826.1|485274_486261_-|LysR-family-transcriptional-regulator
MDRFDAMRAFARVVETGSFTKAADTLHMSKTSVTQLVQQLEARLRVRLLNRTTRKVNATADGAAYYERVRQLLADLEDAETSLSGASATPGGRLRVDVPSPFASTILVPALPAFQARYPDILLHLGVSDREVDLIDENVDCVIRGGQIGNLSLAARHVGDLQLGVYASPGYLARAGVPAHPRELQDAQHRIIGFSWSRARRLFPCAMRRADERIEVAGRHALLLDEGNAYLAAGLAAMGMIGVPTYMAEAHVERGALIRLFGDWRLDPMPLYIAYPQNRHVSAKLRVFIDWIVELMARHAPVTDAPPPHRSARMPGGPAAIPPDITGA

Crispr_ID: NC_018828_2

• CRISPR_ID: NC_018828_2
• CRISPR_location: 1222624-1222728
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_018828_2

Consensus_repeat	Method
CGCTGCGCCAGCTTGCTGCCCCCCAGGGGGGCTTT	CRISPRCasFinder

spacers of NC_018828_2

>2.1|1222659|35|NC_018828|CRISPRCasFinder
GCCTTGGGGCGGCCCGGCGGTGGAAAATGCCCCCA

CRISPR arrays and Neighbor proteins around NC_018828_2

CRISPR arrays

The CRISPR arrays of NC_018828_2

>merge|NC_018828|2|1222624-1222728|CRISPRCasFinder
CGCTGCGCCAGCTTGCTGCCCCCCAGGGGGGCTTTGCCTTGGGGCGGCCCGGCGGTGGAAAATGCCCCCACGCTGCGCCAGCTTGCTGCCCCCCAAGGGGGCTTT

>NC_018828|2|2|1222624-1222728|CRISPRCasFinder
CGCTGCGCCAGCTTGCTGCCCCCCAGGGGGGCTTT	GCCTTGGGGCGGCCCGGCGGTGGAAAATGCCCCCA
CGCTGCGCCAGCTTGCTGCCCCCCAAGGGGGCTTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018828.1|WP_010931458.1|1218591_1219692_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|223506
NC_018828.1|WP_003814195.1|1220153_1220366_-|zinc-finger-domain-containing-protein	unknown	unknown	gnl|CDD|226826
NC_018828.1|WP_015039182.1|1220412_1221333_-|branched-chain-amino-acid-transaminase	unknown	unknown	gnl|CDD|235841
NC_018828.1|WP_003814170.1|1234211_1235261_-|quinone-dependent-dihydroorotate-dehydrogenase	unknown	unknown	gnl|CDD|235388
NC_018828.1|WP_165446299.1|1235301_1236027_-|arginyltransferase	unknown	unknown	gnl|CDD|234939
NC_018828.1|WP_003814183.1|1224763_1225564_+|EI24-domain-containing-protein	unknown	unknown	gnl|CDD|377798
NC_018828.1|WP_003814179.1|1225616_1226429_+|competence/damage-inducible-protein-A	unknown	unknown	gnl|CDD|223986
NC_018828.1|WP_015039185.1|1224318_1224702_-|thioredoxin-family-protein	unknown	unknown	gnl|CDD|239245
NC_018828.1|WP_003814197.1|1219708_1220131_-|SnoaL-like-domain-containing-protein	unknown	unknown	gnl|CDD|379209
NC_018828.1|WP_015039187.1|1233485_1234064_+|TIGR01841-family-phasin	unknown	unknown	gnl|CDD|130900
NC_018828.1|WP_015039181.1|1216062_1216902_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl|CDD|224131
NC_018828.1|WP_003814178.1|1226587_1227436_+|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NC_018828.1|WP_003814164.1|1236063_1236828_-|leucyl/phenylalanyl-tRNA--protein-transferase	unknown	unknown	gnl|CDD|234720
NC_018828.1|WP_003814188.1|1222267_1222597_+|AzlD-domain-containing-protein	unknown	unknown	gnl|CDD|226827
NC_018828.1|WP_015039179.1|1213983_1215078_+|porin	unknown	unknown	gnl|CDD|238208
NC_018828.1|WP_015039186.1|1232122_1233100_-|tripartite-tricarboxylate-transporter-substrate-binding-protein-BugD	unknown	unknown	gnl|CDD|270294
NC_018828.1|WP_164926465.1|1215168_1216041_+|cytochrome-c-oxidase-assembly-protein	unknown	unknown	gnl|CDD|378238
NC_018828.1|WP_033473099.1|1222954_1224307_+|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|236722
NC_018828.1|WP_003814201.1|1216977_1218495_+|M48-family-metallopeptidase	unknown	unknown	gnl|CDD|227122
NC_018828.1|WP_164926466.1|1221515_1222265_+|AzlC-family-ABC-transporter-permease	unknown	unknown	gnl|CDD|224215

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018828.1|WP_010931458.1|1218591_1219692_-|alpha/beta-fold-hydrolase	gnl|CDD|223506	COG0429, COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only].	1.04959e-90
NC_018828.1|WP_003814195.1|1220153_1220366_-|zinc-finger-domain-containing-protein	gnl|CDD|226826	COG4391, COG4391, Uncharacterized protein conserved in bacteria [Function unknown].	5.98518e-12
NC_018828.1|WP_015039182.1|1220412_1221333_-|branched-chain-amino-acid-transaminase	gnl|CDD|235841	PRK06606, PRK06606, branched-chain amino acid transaminase.	0
NC_018828.1|WP_003814170.1|1234211_1235261_-|quinone-dependent-dihydroorotate-dehydrogenase	gnl|CDD|235388	PRK05286, PRK05286, quinone-dependent dihydroorotate dehydrogenase.	0
NC_018828.1|WP_165446299.1|1235301_1236027_-|arginyltransferase	gnl|CDD|234939	PRK01305, PRK01305, arginyl-tRNA-protein transferase; Provisional.	7.23501e-140
NC_018828.1|WP_003814183.1|1224763_1225564_+|EI24-domain-containing-protein	gnl|CDD|377798	pfam07264, EI24, Etoposide-induced protein 2.4 (EI24). This family contains a number of eukaryotic etoposide-induced 2.4 (EI24) proteins approximately 350 residues long as well as bacterial CysZ proteins (formerly known as DUF540). In cells treated with the cytotoxic drug etoposide, EI24 is induced by p53. It has been suggested to play an important role in negative cell growth control.	1.28978e-07
NC_018828.1|WP_003814179.1|1225616_1226429_+|competence/damage-inducible-protein-A	gnl|CDD|223986	COG1058, CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only].	2.67138e-63
NC_018828.1|WP_015039185.1|1224318_1224702_-|thioredoxin-family-protein	gnl|CDD|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	9.92654e-14
NC_018828.1|WP_003814197.1|1219708_1220131_-|SnoaL-like-domain-containing-protein	gnl|CDD|379209	pfam13474, SnoaL_3, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	1.07341e-14
NC_018828.1|WP_015039187.1|1233485_1234064_+|TIGR01841-family-phasin	gnl|CDD|130900	TIGR01841, hypothetical_protein, phasin family protein. This model describes a family of small proteins found associated with inclusions in bacterial cells. Most associate with polyhydroxyalkanoate (PHA) inclusions, the most common of which consist of polyhydroxybutyrate (PHB). These are designated granule-associate proteins or phasins; the member from Rhodospirillum rubrum is an activator of polyhydroxybutyrate (PHB) degradation. However, the member from Magnetospirillum sp. AMB-1 is called a magnetic particle membrane-specific GTPase.	2.14387e-10
NC_018828.1|WP_015039181.1|1216062_1216902_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl|CDD|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	4.12601e-156
NC_018828.1|WP_003814178.1|1226587_1227436_+|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	4.34506e-72
NC_018828.1|WP_003814164.1|1236063_1236828_-|leucyl/phenylalanyl-tRNA--protein-transferase	gnl|CDD|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	3.07893e-129
NC_018828.1|WP_003814188.1|1222267_1222597_+|AzlD-domain-containing-protein	gnl|CDD|226827	COG4392, COG4392, Predicted membrane protein [Function unknown].	7.8037e-15
NC_018828.1|WP_015039179.1|1213983_1215078_+|porin	gnl|CDD|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	1.17522e-51
NC_018828.1|WP_015039186.1|1232122_1233100_-|tripartite-tricarboxylate-transporter-substrate-binding-protein-BugD	gnl|CDD|270294	cd13576, PBP2_BugD_Asp, Aspartic acid transporter of Bug (Bordetella uptake gene) protein family; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) receptors present in a number of bacterial species, but mainly in proteobacteria. Bug proteins are the PBP components of the tripartite carboxylate transporters (TTT). Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	4.42532e-160
NC_018828.1|WP_164926465.1|1215168_1216041_+|cytochrome-c-oxidase-assembly-protein	gnl|CDD|378238	pfam09678, Caa3_CtaG, Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG). Members of this family are the CtaG protein required for assembly of active cytochrome c oxidase of the caa3 type, as found in Bacillus subtilis.	4.2222e-45
NC_018828.1|WP_033473099.1|1222954_1224307_+|DEAD/DEAH-box-helicase	gnl|CDD|236722	PRK10590, PRK10590, ATP-dependent RNA helicase RhlE; Provisional.	5.04627e-156
NC_018828.1|WP_003814201.1|1216977_1218495_+|M48-family-metallopeptidase	gnl|CDD|227122	COG4783, COG4783, Putative Zn-dependent protease, contains TPR repeats [General function prediction only].	4.64199e-95
NC_018828.1|WP_164926466.1|1221515_1222265_+|AzlC-family-ABC-transporter-permease	gnl|CDD|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	7.97411e-32

Protein sequences

>NC_018828.1|WP_003814188.1|1222267_1222597_+|AzlD-domain-containing-protein
MSDRDLYVYGAILLLTLCSVLTRAGFMLFGDYIPLPDGVRRALRYAPAAALTAIVVPDLLPWKAGLGPAFDYKLVAGVLAIMAFLRTRSAVLVIVVGMVALWGLRWLAG
>NC_018828.1|WP_164926466.1|1221515_1222265_+|AzlC-family-ABC-transporter-permease
MASDPATSALEDARQARQERADAFRAGVRAITPALIATGTWGMVTGVAMVKSGLTESMALAMTLLMYAGSAQLTSLPLIATGVPLWLIFAAGFVVNLRFLIFGAALHPYFRHMSWPRRLGLGYFTTDMGFVLFMPRFGDAAERGTREQLWFFLGTVAPDWMVWQVTSIVGIYLGSLVPEAWSLDFAAVLALLAITVPLANSKPMLVSMLAAGMVAWVGQLLPLRLGLAAAVVAGIVAGIWAERFFKGRT
>NC_018828.1|WP_015039182.1|1220412_1221333_-|branched-chain-amino-acid-transaminase
MSMSDRDGFIWYDGKLVPWREATTHVLTHSLHYGLSVFEGVRAYETAAGTAIFRLQDHTNRLFNSAHIYQIPLPYDRDTLNEAQREVVRANGLASCYLRPLAFYGSEKMGVSPKGAQVHVAIAAWPWGAYLGETALAQGIRVKVSSFARQHVNVTMPRAKVATTYANSIIANAEALQDGYDEALLLDTEGFVAEGAGENIFIVKDGVLCEPEIASALTGITRSTIHALAADLGLRVVTKRLTRDDVYIADEAFFTGTAAEVTPIREVDNRQIGTGRRGPVTEKLQQAFFDLVNGRNPKYQHWLTPV
>NC_018828.1|WP_003814195.1|1220153_1220366_-|zinc-finger-domain-containing-protein
MTAAAQAAVPAHDAIEVGAEDLPVYCPGPKAPLWSMHPRVFLDVTHTGQASCPYCGAAYRLKPGTVVHGH
>NC_018828.1|WP_003814197.1|1219708_1220131_-|SnoaL-like-domain-containing-protein
MFATPDEAEHAFYEALEHADLDRLMQVWSDDEEIACIHPGGLRIVGHTAVHESWQQVLANGPLHLRPLRPLVMQSMMCAVHVLVEQVTVMTREGAQFANCYATNVYHKGPAGWRMVLHHASQAPAEAGVLDLHDFPDRLH
>NC_018828.1|WP_010931458.1|1218591_1219692_-|alpha/beta-fold-hydrolase
MAASRIDLTPCPVPPWLPDRHSQTVYAAALAQYHRIAFVRERVDTPDTDFVDFDWTGPGLFPHKTAEGAAPAGPAPQGNGRIAAARWITATDWASLPQTADTPALILFHGLEGGSASRYAQSIAHYFRARGWIVVIAHFRGCSGVPNRLARAYYSGDSAEVGFMLDTVRARIPHARWHAVGVSLGGNALLKYLGEHHDEASWLAAAAGVSVPLDLVAGGKALCTGFIARRIYTAYFLKTMRRKVLEKAKRFPGAIDVIRIAHARDLRDFDDAYTARMHGYRNALDYWTRASSKPWLAHIKTPTLVLNARNDPFLPESALPIPAECSDSVLLHQPAEGGHAGFPTGPFPAHLNWLPQRLGRFFEMGS
>NC_018828.1|WP_003814201.1|1216977_1218495_+|M48-family-metallopeptidase
MNRWNLTFSPSLGRRALAAALSLALGLPVAPAVGQPSGLPSMGAASASELSPMLERQLGDAIMAQGRRDPTYINDPELRQYLTTMGRKLASFAPGAAPHVEMFGVRDPEINAFAMPGGYIGVNTGLIVSSASESELAAVLAHEIGHVAQRHIARGMTQQNQNSMVMLASLAGALLAALAGGGGNLAMGVAAFGQAAAINRQLGFSRDAEREADRTGLQMLAKAGYDPDGMAQMFSRLMNASRLNEGMGGGAWASTHPLSIDRMSDVQNRIRGLPGSRHVDSDDFWFIRAKMRVAQGRDALSLRTAQQQLQDESRALSGVRQAAAFYGLALYAFQRNDLAQARAFLEQAGAGGRSSPQMARLAIDVAVAAKDNDQALALAQAAVKRWPDRKALGIAYAQALQAAGRHADAQAYLRERARQWGGDEPSLYQLLAQSEERTGHPVDARRNMARYYDLTGAYASAESQLQQARGLSNDFYEQSQIDVSIREIKQKLADERQLLERFKSG
>NC_018828.1|WP_015039181.1|1216062_1216902_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MQVVRKAVFPVAGMGTRFLPATKAMPKEMLPVVDKPLIQYAVEEAVAAGITDLIFVTGRNKRAIEDHFDAAPELETDLEAKGKHELLALVRDILPAHVNCLYIRQSAPLGLGHAVLTAAPAVGNEPFAVLLADDLIDADTPVLKQLIDVAVARQGSVLGVQEVPREDTRKYGIVASQPVDARTERITHIVEKPAPEQAPTTLAVVGRYVLEAAIFDHLRATTVGAGNEIQLTDGIAALLRERDVYAHRYDGKRYDCGSKAGMFQATVALGRKYHGLIPE
>NC_018828.1|WP_164926465.1|1215168_1216041_+|cytochrome-c-oxidase-assembly-protein
MDWLEWLIPWEFSPTLVAAFVVAIVLFVRGQRVHHVTAARQWLFWSGMVLLYLSMHTRLDYYAERMFFIHRAQHLVLHHLGPLLVMAAFPGSAMRAGLPMAWRVRLRDFLRTGTGRALAAVLTHKVFVPTLFVFLVLVWLLPSVQFYSMLDWRLYRLMNWSVVISGFMYWNLILDRRPSPPAAMTPGGRVLSPALTMAPQMVAGAVIAFTERDLYPLFELCGRAIAMSAQTDQTIGGLTMWIPVALVEVVGLLVALGTLMRLSGKGRLRPQDRAARARQRAAGSPTSPAA
>NC_018828.1|WP_015039179.1|1213983_1215078_+|porin
MRRLLVVAAMAAGSSSVFWSVAPARAANQLELYGVVDVGLATTRVSGLGTRQQVLGGGQTDNLWGLRGTEELDGGWRASFGLESGFDAVNGTRNDDARLFDYGTWVGLGHAGVGELSLGRQQSIGLQYGGQLEIASWRDMGMGALFKASDNYRVNNLVNYLSPEFSGWQWGVGYAFDVESGDTGRFDRSPAFSTGLKYEDGPLLAAFTWDKLNLHDTSATGGRSPQALQAGFTYDFEALKMALAWSRQRNGFVGLNGGGQIGLGPEPFAHGGAINAWLLGLEVPVHGNGAWLVQGSMARPDWYWANGQQASKAYVVTLGYRQDLSARTSLYAYGGYMKGYDPEDPFASDVGRATRFGVGMTQRF
>NC_018828.1|WP_033473099.1|1222954_1224307_+|DEAD/DEAH-box-helicase
MLKSIADTGYTNPTPIQAQAIPVVVEGRDVMGAAQTGTGKTAAFTLPILHRLMPLANTSASPARHPVRALILTPTRELADQVYESVKRYSLHTPLRSAVVFGGVDIGPQKEALRRGCEVLVATPGRLLDHVEQKNVNLSQVGILVLDEADRMLDMGFLPDLERIIRLLPAQRQGLLFSATFSNEIRKLGRSYLNHPVEIEVAARNATADTVTQIAYQMHGDTKRAAVVHLVKSRGLKQVIVFSNTKIGTARLARQLERDGVKAESIHGDKTQGDRMKALEAFKAGDLEVLVATDVAARGLDVAGVPCVINYDLPYNAEDYVHRIGRTGRAGASGEAIALFTADEERYLLDIEKLIKRQVPRGKLELPADLVARSHGRDRDAPRERGADRHRGERRTSGAAAPRQPVDELFYKPYEPANGQPASPETPEQEGRSNAPKRQLAVLLGGSRKG
>NC_018828.1|WP_015039185.1|1224318_1224702_-|thioredoxin-family-protein
MPLHVPGSDIPTLRAALARSDAWLVACFCAAWCDTCQQYRSKLLELARARPGHTFAWIDIEDHPDLLGEEDVENFPTLLVQAHGKVLFYGPMLPHIGHLERLLDSLDPQGRPVATGLPDVARLLAAA
>NC_018828.1|WP_003814183.1|1224763_1225564_+|EI24-domain-containing-protein
MTVPRPESIIPPAGNAATGAAGIARAFKRALVSQCHPNMLFAVLLPFLIALLGAILLLWLFWTPLNEWLRFEASQWQAINQVDDWMVAAGLFSLKIYLVPVIAAAILLPISGILGLAIAAVFVMPLVLRHVGGREYAGLARQGRNATAVSVWNALWVSLAFGAGWLLTLPFWLIPPMAVILSVFWWAFAFTRMLRLDAIVEHASPAERAILLKRHNSGFWLIGLVCSLLNLLPPAWIILPVFSGLVYAHYGLDALQRLRQERTIDV
>NC_018828.1|WP_003814179.1|1225616_1226429_+|competence/damage-inducible-protein-A
MAAESARRIGLIIVGDEILSGRRQDKHFSKVVELLGARGLKLSWAELLPDDRATLAAVLRRSFASGDIVFSCGGIGGTPDDHTRQAAAEALDLPLALHPEAEQAIALRAAEMAAKGQGTADMGTPENQQRLQMGMFPRGCEIVPNPYNRIPGFFVRDHTFVPGFPVMAWPMLEWTLDTRYRALHHQVRHAEHSFLVFDMPESRITPAMVEIEQRWPGVRAFSLPSVGETGGPSHIDLGVKGEPEAAAQALAFLRAEVVRLGGKLAPPAQN
>NC_018828.1|WP_003814178.1|1226587_1227436_+|IclR-family-transcriptional-regulator
MSRIPNATARGPGSHSDDGAGQHPIAIQVIDRAMRLLDALAAQPEPVTLKELSATTGLHASTAHRILNDLVVGRYVERVDNGLYQLGMRLLELGSLVKGRLNVREAAIGAMRSLHKQTGQTINLSVQQGDEIVYIDRAWSERSGMQVVRAIGGRAPLHLTSTGKLFLSTYDTRLVRAYALRTGLAGHTRNSLTELDRLERELALVRRHGYARDNEELELGVRCIAAGIYDDTGKLVAGLSISAPAERLQDEWIRLLVDAAASISEALGYEPGVNGIHAPAAA
>NC_018828.1|WP_015039186.1|1232122_1233100_-|tripartite-tricarboxylate-transporter-substrate-binding-protein-BugD
MPPISRKLSALFAAVALTGAGTALAEYPERPVNMVVPFAAGGPTDNVARSLAESMRPTLGETVVVENKGGAGGTIGTTQVARAQPDGYSILLMHAGFSTAPSLYKNPGYEPYTSFEPIGLVVDVPMTIIARGDFPPNNIKELAEYVKKNADKISLANAGIGAASHLCGTMLVEALGVNLLTIPYKGTAPAMNDLLGKQVDLMCDQTTNTTQQITSGKVKAYAVTSLKRVPTLLDLPTMDESGYKGFEVGIWHGMWAPKGTPKPVVDKLVKSLQAGLADPKFQERMKQLGAEVLTNEANPEALQAKVKQQVPQWAELFKKAGVEKQ
>NC_018828.1|WP_015039187.1|1233485_1234064_+|TIGR01841-family-phasin
MSAIPQQVLARQKATVNSLVAAQSAMFAGFERLVDLNLKVVRATLDEVAQQSQQAAELKDPQDVASFTSGLVQPGAEKALAYGKHVYDIVAGVQAELAQLAEAQIAEGQQQLTEAVEQFSKNAPTGSESAVALIKSSLATANSAYDSLTKAAKQAAEVAESNLNAAANASFKAASDAAEVATKAAGRNRRAA
>NC_018828.1|WP_003814170.1|1234211_1235261_-|quinone-dependent-dihydroorotate-dehydrogenase
MSILFHAYPLARPALFAMDAETAHEVTLAQLQRAYDCGLTRKLLHAQPEAPATLMGLSLRNPVGLAAGLDKNGAHIDALGNLGFGFVEVGTVTPRAQPGNPKPRMFRLPRANALINRLGFNNQGLDAFIANVQRSQWRSQGGILGLNIGKNADTPIERAAEDYLIGLAGVYPHADYVTVNISSPNTKNLRALQGGDELSALLGQLQERRLALADQHQRHVPLAVKIAPDLSDDQIDAIAEILPRHGIDGVIATNTTLARDAVQGLPHAEEAGGVSGAPVHELSLRVIERLRSRLGDAVAIIGVGGILSGRQASEKMAAGAQAVQLYTGLIYRGPALVGECVRALAQGSR
>NC_018828.1|WP_165446299.1|1235301_1236027_-|arginyltransferase
MSQLKELPFSTLQFYATAPYPCSYLPGRQARSQVAAPGHLINAGTYSQLVEQGFRRSGLFTYRPHCDNCHACVPVRVDAARFEPNRTQRRAWRSHQALRAFVAELAWSPEHYDLYTRYQQGRHPGGGMDEDSRTQYAQFLLTTRVNTRLVEFRTPQGQLAMISIIDVLDDGLSSVYTFYDPDMAGSLGTYSILWQIEQCRTLDLPWLYLGYWIADSRKMAYKANFRPLQMHVDGTWRETPP
>NC_018828.1|WP_003814164.1|1236063_1236828_-|leucyl/phenylalanyl-tRNA--protein-transferase
MKLPWLAADTPFPPVEQALRDPDGLLAAGADLSPERLAQAYAHGIFPWYAEGEPILWWSPDPRMVLACADFAPSHSLRKRLRALARTEHDPAARLQVRVDTAFARVLHECAAPRHGQPGTWISPAVQQAYRSWHAAGFVHSIETWIDGELAGGLYGVSLGRMFYGESMFARATDASKIALAHLVAFLRRHQVAWIDCQQQTGHLARLGARPVPRARFIEHIAHAVAQPRLPWRSGRLDSAGMLHPLPPANGVMM

Crispr_ID: NC_018828_3

• CRISPR_ID: NC_018828_3
• CRISPR_location: 1325598-1325684
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_018828_3

Consensus_repeat	Method
AGTGTGCCTGTCCCCGCAGGGACAG	CRISPRCasFinder

spacers of NC_018828_3

>3.1|1325623|37|NC_018828|CRISPRCasFinder
ATACCGTCTTGGCGGGCTAGCGTCGATGGCGTACGGC

CRISPR arrays and Neighbor proteins around NC_018828_3

CRISPR arrays

The CRISPR arrays of NC_018828_3

>merge|NC_018828|3|1325598-1325684|CRISPRCasFinder
AGTGTGCCTGTCCCCGCAGGGACAGATACCGTCTTGGCGGGCTAGCGTCGATGGCGTACGGCAGTGTGCCTGTCCCCGCGGGGACAG

>NC_018828|3|3|1325598-1325684|CRISPRCasFinder
AGTGTGCCTGTCCCCGCAGGGACAG	ATACCGTCTTGGCGGGCTAGCGTCGATGGCGTACGGC
AGTGTGCCTGTCCCCGCGGGGACAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018828.1|WP_010929073.1|1315183_1315870_-|hypothetical-protein	unknown	unknown	gnl|CDD|225396
NC_018828.1|WP_015039233.1|1332037_1333351_+|xanthine/uracil-family-permease	unknown	unknown	gnl|CDD|132655
NC_018828.1|WP_015039235.1|1337846_1339733_+|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	unknown	unknown	gnl|CDD|273520
NC_018828.1|WP_004568205.1|1331586_1331904_-|hypothetical-protein	unknown	unknown	unknown
NC_018828.1|WP_015039230.1|1325715_1326360_-|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NC_018828.1|WP_015039231.1|1326370_1327258_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NC_018828.1|WP_010930947.1|1316848_1319218_+|DNA-translocase-FtsK	unknown	unknown	gnl|CDD|236669
NC_018828.1|WP_005014990.1|1322984_1323221_+|hypothetical-protein	unknown	unknown	unknown
NC_018828.1|WP_003814026.1|1321338_1322694_+|serine--tRNA-ligase	unknown	unknown	gnl|CDD|235461
NC_018828.1|WP_003814033.1|1315856_1316816_-|thioredoxin-disulfide-reductase	unknown	unknown	gnl|CDD|182343
NC_018828.1|WP_015039234.1|1335526_1336003_+|transcription-elongation-factor-GreA	unknown	unknown	gnl|CDD|234693
NC_018828.1|WP_003814030.1|1319217_1319850_+|outer-membrane-lipoprotein-chaperone-LolA	unknown	unknown	gnl|CDD|178807
NC_018828.1|WP_003814037.1|1314854_1315187_-|multidrug-transporter	unknown	unknown	gnl|CDD|137367
NC_018828.1|WP_164926474.1|1319951_1321292_+|replication-associated-recombination-protein-A	unknown	unknown	gnl|CDD|237355
NC_018828.1|WP_003809621.1|1336976_1337609_+|RlmE-family-RNA-methyltransferase	unknown	unknown	gnl|CDD|223370
NC_018828.1|WP_015039232.1|1330163_1331486_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270236
NC_018828.1|WP_015038907.1|1323365_1324586_-|ISL3-like-element-IS1001-family-transposase	unknown	unknown	gnl|CDD|225995
NC_018828.1|WP_003809599.1|1327305_1328391_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226361
NC_018828.1|WP_003809618.1|1336355_1336958_-|YhbY-family-RNA-binding-protein	unknown	unknown	gnl|CDD|198171
NC_018828.1|WP_015039227.1|1312792_1314841_+|cation-acetate-symporter	unknown	unknown	gnl|CDD|274698

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018828.1|WP_010929073.1|1315183_1315870_-|hypothetical-protein	gnl|CDD|225396	COG2840, COG2840, Uncharacterized protein conserved in bacteria [Function unknown].	6.4148e-36
NC_018828.1|WP_015039233.1|1332037_1333351_+|xanthine/uracil-family-permease	gnl|CDD|132655	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the uracil-xanthine permease family defined by TIGR00801. As well as the The Nucleobase:Cation Symporter-2 (NCS2) Family (TC 2.A.40).	0
NC_018828.1|WP_015039235.1|1337846_1339733_+|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	gnl|CDD|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NC_018828.1|WP_015039230.1|1325715_1326360_-|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	1.05965e-69
NC_018828.1|WP_015039231.1|1326370_1327258_-|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	9.7001e-34
NC_018828.1|WP_010930947.1|1316848_1319218_+|DNA-translocase-FtsK	gnl|CDD|236669	PRK10263, PRK10263, DNA translocase FtsK; Provisional.	0
NC_018828.1|WP_015039227.1|1312792_1314841_+|cation-acetate-symporter	gnl|CDD|274698	TIGR03648, Na_symport_lg, probable sodium:solute symporter, VC_2705 subfamily. This family belongs to a larger family of transporters of the sodium:solute symporter superfamily, TC 2.A.21. Members of this strictly bacterial protein subfamily are found almost invariably immediately downstream from a member of family TIGR03647. Occasionally, the two genes are fused.	3.98343e-142
NC_018828.1|WP_003814026.1|1321338_1322694_+|serine--tRNA-ligase	gnl|CDD|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NC_018828.1|WP_003814033.1|1315856_1316816_-|thioredoxin-disulfide-reductase	gnl|CDD|182343	PRK10262, PRK10262, thioredoxin reductase; Provisional.	3.05616e-163
NC_018828.1|WP_015039234.1|1335526_1336003_+|transcription-elongation-factor-GreA	gnl|CDD|234693	PRK00226, greA, transcription elongation factor GreA; Reviewed.	3.0461e-82
NC_018828.1|WP_003814030.1|1319217_1319850_+|outer-membrane-lipoprotein-chaperone-LolA	gnl|CDD|178807	PRK00031, lolA, outer membrane lipoprotein chaperone LolA.	1.55834e-67
NC_018828.1|WP_003814037.1|1314854_1315187_-|multidrug-transporter	gnl|CDD|137367	PRK09541, emrE, EmrE family multidrug efflux SMR transporter.	1.994e-34
NC_018828.1|WP_003809621.1|1336976_1337609_+|RlmE-family-RNA-methyltransferase	gnl|CDD|223370	COG0293, FtsJ, 23S rRNA methylase [Translation, ribosomal structure and biogenesis].	1.10576e-83
NC_018828.1|WP_015039232.1|1330163_1331486_-|extracellular-solute-binding-protein	gnl|CDD|270236	cd13518, PBP2_Fe3_thiamine_like, Substrate binding domain of iron and thiamine transporters-like, a member of the type 2 periplasmic binding fold superfamily. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria from the Pasteurellaceae and Neisseriaceae families and is critical for survival of these pathogens within the host. On the other hand, thiamin is an essential cofactor in all living systems. Thiamin diphosphate (ThDP)-dependent enzymes play an important role in carbohydrate and branched-chain amino acid metabolism. Most prokaryotes, plants, and fungi can synthesize thiamin, but it is not synthesized in vertebrates. These periplasmic domains have high affinities for their respective substrates and serve as the primary receptor for transport. After binding iron and thiamine with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The iron- and thiamine-binding proteins belong to the PBPI2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	8.71174e-40
NC_018828.1|WP_015038907.1|1323365_1324586_-|ISL3-like-element-IS1001-family-transposase	gnl|CDD|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.9636e-80
NC_018828.1|WP_003809599.1|1327305_1328391_-|ABC-transporter-ATP-binding-protein	gnl|CDD|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	3.76041e-148
NC_018828.1|WP_003809618.1|1336355_1336958_-|YhbY-family-RNA-binding-protein	gnl|CDD|198171	smart01103, CRS1_YhbY, Escherichia coli YhbY is associated with pre-50S ribosomal subunits, which implies a function in ribosome assembly. GFP fused to a single-domain CRM protein from maize localises to the nucleolus, suggesting that an analogous activity may have been retained in plants. A CRM domain containing protein in plant chloroplasts has been shown to function in group I and II intron splicing. In vitro experiments with an isolated maize CRM domain have shown it to have RNA binding activity. These and other results suggest that the CRM domain evolved in the context of ribosome function prior to the divergence of Archaea and Bacteria, that this function has been maintained in extant prokaryotes, and that the domain was recruited to serve as an RNA binding module during the evolution of plant genomes. YhbY has a fold similar to that of the C-terminal domain of translation initiation factor 3 (IF3C), which binds to 16S rRNA in the 30S ribosome.	1.06237e-30
NC_018828.1|WP_164926474.1|1319951_1321292_+|replication-associated-recombination-protein-A	gnl|CDD|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0

Protein sequences

>NC_018828.1|WP_015038907.1|1323365_1324586_-|ISL3-like-element-IS1001-family-transposase
MLDRKLLESLGSWQGYGVERVEWPEDPGRTLSIYLKPTAKVMLCEQCGARCRQVHETTVRRVRDLPLFEYRVVLHVPRRRLWCEQCGGPRLERLAWLGRYQRVTDRLAQACSQLLQSSNVQAVARFFELGWHTVKTLDKARLRASVREPDWSKIEYLAMDEFALHKGHRYATVVVDPIGRQVLWIGPGRSRETARAFFEQLPPGAAQRIKAVAIDMTTAYELEIQAHSPQAEIVYDLFHVVAKYGREVIDRVRVDQANQLRQDRPARRIIKSSRWLLLRNRDNLDRQQAVRLDELLQANQPLLTVYVLRDELKRLWFYQRPAWARQAWNHWYEQAEQSGIPALNTFAQRLKGYLHGILARCRHPLNTSIVEGINNTIKVIKRRAYGYRDQEYFFLKIRAAFPGNAR
>NC_018828.1|WP_005014990.1|1322984_1323221_+|hypothetical-protein
MIGDFRVRCTVVQEEGNQYSVQICTRRVGGNAPEKCWTVPGQVSYQDREDAERTSQQIFERINGVRFNGEPEFAHASA
>NC_018828.1|WP_003814026.1|1321338_1322694_+|serine--tRNA-ligase
MLDPILLRKDLQTVVDRLKSRGVDFDIARFNELESRRKAVQTETESQQARRNALAKQIGQLKGKGAPEAEVQAVMAESQALPARLKALEDELAQTQAQLNDLLMSVPNLPHASVPQGASSDENVEVRRWLPGAADERGNPAALGFEVRDHVAVGEPLGLDFDLAARLSGARFSFMRGQMARLHRALAQFMLDLQTGTHGYTECYTPYIVNSSTLFGTGQLPKFKDDMFFVTKGGGDDEPKVDEQGNPLAREDQYLISTSEITLTSVVRETIVAGADLPLRLTAHTPCFRSEAGSGGRDTRGMIRQHQFDKVEMVQIAHPEHSYEALEEMVGHAERVLQLLELPYRVMLLCTGDMGFGSAKTYDLEVWLPAQDTWREISSVSNCETFQARRMQARFRNAQNKPEYVHTLNGSGLAVGRALVAVLENCQQADGSVRVPAVLQPYMGGLTVLEP
>NC_018828.1|WP_164926474.1|1319951_1321292_+|replication-associated-recombination-protein-A
MSNDLFASDPAHRPYVPLAERLRPRTLSDVVGQSHLLGSDKPLRVAFDSGRPHSMIFWGPPGVGKTTLARLMADGFDAQFIAISAVLGGVKDIRDAVVTAQVAQGQGRRTILFVDEVHRFNKSQQDAFLPYVESGLFTFIGATTENPSFEVNSALLSRARVYVLQSLSAEELMQLVDRAVAALNEGLEDGQQIRFEAEAREQLAAWADGDARRLISAVEVVAESAQAAGRDSVDAAWLETSLSQNLRRFDKGGDAFYDQISALHKSVRGSDPDAALYWLARMLDGGADPKYLARRLVRMAIEDIGLADPRATELAVNGADIYERLGSPEGELALAQAVVYMACAAKSNAVYNAYNAARKFAAEHGSAPVPLHLRNAPTKLMKQLGHGKAYRYVHDQPHAYAADEQYFPDGLNPTFYRPTDRGLEAKIQQKLAFLDELDAQERARKR
>NC_018828.1|WP_003814030.1|1319217_1319850_+|outer-membrane-lipoprotein-chaperone-LolA
MHMIRRAAGALAVFAVAALAAAPAWAATAQEQLDTFVATVKGATGSFKQSTVSPQGATQPAQSGTFAFQRPGKFKWAVQLPYEQLIVSDGKQVFQYDPDLAQVTVRQVDQAIGTSPAAILFGAGQLGQAFAVSALPDRDGLQWLRAKPRNADAGFSQVDIGLRDNQPARIELVDAFGQTTRVELSNLLPGAVPASEFQFTPPQGVDVVKM
>NC_018828.1|WP_010930947.1|1316848_1319218_+|DNA-translocase-FtsK
MSRMPRISNATPRASRNTRNGPSPFQARISALLREARWILFAALAAWLTLVLATWSPADPGWSHSVSGDAIHNGGGTLGAYLADILLYLFGFSAWWWVVLLLHRVRAGYRRLASNLRVTSGKQPDALPRVHWEEGIGFVLLLTGSLGIEALRLYSWGMHLPGGTDGESGAGGVIGQMLAGWLSRGVGFTGGTLALLVLLAVGLSLFFSFSWLQIAERVGSWLEGLVRRVRDSYAAREDRKVGEVAKAVRTEQVVAKQEKLVHEQPVRIEPAITVVPRSDRAEKEKQQSLFAPPAGESDLPAIGLLDPPLQNQETVSAETIEFTSRLIEKKLADFGVSVVVVAAQAGPVITRYEIEPATGVKGSQIVNLAKDLARALSLVSIRVVETIPGKNLMGLELPNPRRQMVKLSEILGSQTYHASHSVLTMALGKDIAGNPVVADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKADASHTRLILIDPKMLEMSVYEGIPHLLAPVVTDMRHAANALNWCVGEMEKRYRLMSKMGVRNLAGYNSKIRDAIKREEPIPNPFSLTPDAPEPLQALPHIVVVIDELADLMMVVGKKIEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILDQMGAETLLGQGDMLYMPPGTGLPVRVHGAFVHDDEVHRVVEALKAQGEPNYIDGLLEGSEGETGDGLSSVTGMGDAESDPMYDQACEVVLKHRRASISLVQRHLRIGYNRAARLLEQMEQAGMVSPMQSNGNREILVPAREEA
>NC_018828.1|WP_003814033.1|1315856_1316816_-|thioredoxin-disulfide-reductase
MSTPKHAKVLILGSGPAGYTAAVYAARANLSPALITGLAQGGQLMTTTEVDNWPADVQGVQGPDLMQRFLQHAERFNTEILFDHVAKVDLSRRPFTLTGDTGNLYTCDALIIATGASAKYLGLASEQAFMGRGVSGCATCDGFFYRNKDVVVIGGGNTAVEEALYLSNICRKVTLIHRRDKFRAEPILVDKLMDKVANGNMELKLFHTLDEVLGDDSGVTGVRIRSTETDATEDLDVAGCFVAIGHQPNTGIFEGQLEMKDGYIITKSGLSGMATMTSVPGVFAAGDVQDHVYRQAITSAGTGCMAALDAQRWLENAGQ
>NC_018828.1|WP_010929073.1|1315183_1315870_-|hypothetical-protein
MRGNKTGLADLKRLHEQVRETRARAEAAEREAAARASAAAPEADVAAFRRAVQAATPLKPSGRLANRRPDATPATAAAVASRRAAALGEAAPRADAGVSDASDIGALLTDGGTAYVRAGVAPDTARNLKRGQWRVGAELDLHGLRVEQARHAVLSFLDECLEHGIRCVRIVHGKGYGSQGLEPVLKDKARTWLVQKADVLAFSEAPERGGGAGALLVLLRQAEAGGRP
>NC_018828.1|WP_003814037.1|1314854_1315187_-|multidrug-transporter
MNSWIHLSVAIVAEIIATSALKSSEGFTRLLPSLVTVAGYAIAFYFLALTLRVIPVGVAYAIWSGVGIVLISLVGALLFKQHLDLPAIIGIALILAGVVVMNVFSKSVGH
>NC_018828.1|WP_015039227.1|1312792_1314841_+|cation-acetate-symporter
MPFTGNTPQEFEQRLRRIYTLYTLGFILLVLLLALAELMGMARSWIGYVFLLVTVSLYACIGIVCRTSDQVEYYVAGRRVPAFYNGMATAADWMSVASFIGVAGTLYLTGYGGLAYIMGWTGGYVLVALLLAPYLRKFGQYTIPDYLGARYGGKLPRLAGVFCAILCSFTYLVAQIYGVGIITTRLTGISFELGIFVALGGMLVCSFLGGMRAVTWTQVGQYIILVIAYLVPVVWLSVKHTGMPVPQLSAGTVLQEITEKEVYLAHDPGERAVRQLWRSRADEMDERLRALPDSLAHEKDRLRGRLAQLNASDAPMVEIRSLERELASYPATVEEARTLWSQARATPPVPHAEPFPAEDPRERENMRINFLALVLCLMLGTAGMPHILMRSYTTPSVGEARRSVCWSLLFILLLYFMAPALALLVKYEVYTQVVGTSFLSLPSWVHAWSAVDIHLLDVLDVNRDGIVQLGEISMGADVVVLAMPEIGGLPYVVSGLVAAGGLAAALSTADGLLLTLSNSLSHDTWYRVVSPRMSAGRRVMVSKILLLLVAFGAAWVAARKPADILFMVSAAFSFAASSFFPALVMGVFWRRANKWGATLGMFAGLAATFAYMAHTHPWLREWVFGVTRAEPVDLWWGIQPVAAGVFGAPMAFLTIIVVSLLTPRPDSATEALVDYLREPGGR
>NC_018828.1|WP_015039230.1|1325715_1326360_-|histidine-phosphatase-family-protein
MTEIWFIRHGETDWNRQRRLQGWQDIPLNESGREQARLLAERLRDTASEHPFAALYSSDLKRAHDTAASLSAALQLRVRTEPGIRERGFGVLEGLEMENLEQQAPQAAQAWRSRDPLRALEGGETLGQFQARIIATVDDLAARHAGERILAVTHSGALDIIWRHASGVPLDAPRYAALLNVSINRVAIAQRKWEVLGWGDVEHIGAETGNDVTP
>NC_018828.1|WP_015039231.1|1326370_1327258_-|LysR-family-transcriptional-regulator
MEIYQIRAFVTVARLGNLTKAAEALSLTQPAVTAQLKALEQSLGVALFDRAAGRLSLAKAGEALLPTAEALLVLGAQLKSEARQLQGQLQGVIDLGVPSEQPDFLRLGELAAALRQRLPLVELKTHVLPSTALLEQVGTARLTIVAHPPRGVTWHALRSVRYRIALPASLADTLKRAGWRDIAQLPWLDGPSGSHLHLLLRDMFERHGLAPRVVMQNDDQSNLDALVRAGAGCALLREETALAGAAAGDFIVWGQARADATLGFIAPPEQAGEPMLVALISMIQKIWKPGAAVAT
>NC_018828.1|WP_003809599.1|1327305_1328391_-|ABC-transporter-ATP-binding-protein
MKKVSVECRNIRLSYGRNEVLKDISIHIEPGEFFALLGPSGSGKSTLLRLIAGFNRQSHGQLLVDGRDIGATPPWDRNIGMVFQNYALWPHMTVWDNVAFGLVERRLPRAEIRDKVAAALELVGLADFGRRRPNQLSGGQQQRVALARTIVIEPQVLLLDEPLSNLDKKLRVQMRQDLLSLQRRLGITTIFVTHDQEEAMTTADRMAVLDHGVVQQIGAPSTLFDYPVNRFVANFVGTMNVLEGEVRERSRGGVVLAVDGVGELHLPVNGDAPQAGRLAASFRPHTVLIEMADGTGDARYVWLPGVVESSEFLGEFTRYQVQVGEQRLTADQHHLAGLSPFPVGAPVAVGLEPTQIRLLAA
>NC_018828.1|WP_015039232.1|1330163_1331486_-|extracellular-solute-binding-protein
MQALRPVLAAAIMAACAPALAGTVTVITSFPKDLTQAYKAAFEKAHPDIKLEILNKNTVSGIAFVRETPAGQRPEVFWASAPDAFEVLGRDKLLAKAPDVANPAVPDKIGSYPINDPSGMYMGQALAGYGIIYNTRYIKANKLPAPVEWKDLLAPHWFGHVGITAPSRSGTMHLTVETILQGEGWNDGWGTLLRMSGNASAVTERSFGVPDGVNNGQFGAGPVIDFFGLSSKYSKFPVDFVYPSETAIVPANIALIEGAKNTEEGKKFIAFTLSQAGQELLLEPKISRLPVLPYAALAGKIPPGYPDPAEIAKRSKVHFDADLSQARYYVVQSLFDQTITFRLKELQAATKAIYDDEAKLGERAGQGKAAELLAQARQLAWTPLVDAQRAADPAFLKLFAGNKKDAAVNQQITQLEGEWNGKARANYEQAQKLAREAAAL
>NC_018828.1|WP_004568205.1|1331586_1331904_-|hypothetical-protein
MTVSSVSSRISAGAFDQYARQLRDRAAASGAKDEAGSPAAEALQALQRQLAAIMRQMRQVRESNATAEQQARQLQDLNRQAFAIQGQIQKLLEEQLRLAQRLAAR
>NC_018828.1|WP_015039233.1|1332037_1333351_+|xanthine/uracil-family-permease
MSNTYFPRWRLADDTVPGAVIAPDERLSWPKNIAMGAQHVVAMFGSTVLAPLLMGFDPNVAILMSGIGTLIFFLFVGGRVPSYLGSSFAFIGGVVAVTGYVAPGANANIGVALGAIIACGLVYALIGLVVWAASARGNGARWIKAMMPSVVTGAVVAVIGLNLAPIAAKGAMGSSGFEASMALMTILCVGGIAVYTRGMVQRLLILVGLVLACVIYAVCANGLGLGAPMDFAKVAAAPWFGLPSFAAPVFEPQAMGLIVPVAIILVAENLGHVKAVAAITGQDLDRYVGRAFVGDGVATMVSGAVGGTGVTTYAENIGVMAVTRIYSTLVFVVAAVIALVLGFSPKFGALIQTIPGPVLGGMSVVVFGLIAIAGARIWVVNQVDFSDNRNLIVAAVTLVLGAGDFSVKLGDFSMNGIGTATFGAIILYALLGLARRR
>NC_018828.1|WP_015039234.1|1335526_1336003_+|transcription-elongation-factor-GreA
MSAIPLTVRGAERLQQELHRLKTVERPAVISAIAEARAQGDLSENAEYDAARERQGFIEGRISELEGTLSNAHLIDPTALDAEGRAVFGATVEIEDLDSSDRLTYQIVGDVEADIKSNLISVSSPVARALIGKSEGDVVEVKVPAGVREYEVIGVRYL
>NC_018828.1|WP_003809618.1|1336355_1336958_-|YhbY-family-RNA-binding-protein
MPILELTSRERSDLRSAAHPLRPVVLIGDNGLTDAVLKEIDLALTAHELIKVRAGGDDREAREAMLATICDTLSCAAVHHLGKTLILFRPDLRAAAAKAAADTPAKRRPSEPHTPKKMAAEGKRLTKTRPARKAAEAAAPAAGARPGRDDLNQAGRPARPSTRKASPGHAIPRRSGSALSLRAGARGGLAGRKPARANKR
>NC_018828.1|WP_003809621.1|1336976_1337609_+|RlmE-family-RNA-methyltransferase
MAKNKFSKDWIHQHINDPYVKLAQQKGYRARAAFKLLEILDAEKLMRRGDIVVDLGSAPGSWSQVARERLAGPGGAVDGRIIALDLLPMEPVAGVEFIQGDFREEAVLEQLARMVEGQPVDLVISDMAPNLSGVGVADSARIQHVCELALEFACAHLKPNGALIVKAFHGSGFSQIVQSYKQRFKRVVERKPKASRDKSSETFLVARDLK
>NC_018828.1|WP_015039235.1|1337846_1339733_+|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein
MNNSFSKVAVWMVIALVLFTVFKQFDGRAQTQDGVSYTQFMDDAKAGRIRKVDVQGNVLYVTPDAGRPYSLTSPGDLWMVSDLLKYGVQVSGKAREEPSLLMSIFVSWFPMLLLIGVWIFFMRQMQGGGRGGAFSFGKSRARMLDENTNQVTFADVAGCDEAKEDVQELVDFLRDPSKFQKLGGRIPRGVLMVGSPGTGKTLLAKAIAGEAKVPFFSISGSDFVEMFVGVGAARVRDMFENAKKHAPCIIFIDEIDAVGRQRGAGLGGGNDEREQTLNQMLVEMDGFESGQGVIVIAATNRPDVLDPALLRPGRFDRQVVVPLPDIRGREQILKVHMRKVPLSPNVDATILARGTPGFSGADLANLVNEAALFAARRNGRTVDMSDFEKAKDKIIMGAERRSIVMPEEERKNTAYHESGHAIVARMLPKTDPVHKVTIIPRGRALGVTMQLPETDRYSMDKERLLNTIAVLFGGRIAEEIFMNQMTTGASNDFERATAIARDIVTRYGMTDELGPMVYAENEGEVFLGRSVTKTTHVSEATMQKVDSEIRRIIDEQYGVARKILEDNRARVEVMTSALLEWETIDADQIDDIVNDRPPRPPKTPQGPSDTSDTPPTGLAAGGNTAAAV

Crispr_ID: NC_018828_4

• CRISPR_ID: NC_018828_4
• CRISPR_location: 2259055-2259480
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 7 spacers

Consensus repeat of NC_018828_4

Consensus_repeat	Method
AGCGGCCCTGGCAGCGNC	CRT

spacers of NC_018828_4

>4.1|2259073|30|NC_018828|CRT
CCTGGCAGCGTCCCAGGCAGCGTCCCAGGC
>4.2|2259121|54|NC_018828|CRT
ACTGGCAGCGGCCCTGGCAGCGGCCCTGGCAGCGGCCCTGGCAGCGGCACTGGC
>4.3|2259193|66|NC_018828|CRT
ACTGGCAGCGGCCCTGGCAGCGTCCCAGGCAGCGTCCCAGGCAGCGGCCCTGGCAGCGGCACTGGC
>4.4|2259277|42|NC_018828|CRT
CCTGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGGCACTGGC
>4.5|2259337|30|NC_018828|CRT
CCAGGCAGCGTCCCAGGCAGCGTCCCAGGC
>4.6|2259385|18|NC_018828|CRT
CCAGGCAGCGGCACTGGC
>4.7|2259421|42|NC_018828|CRT
CCAGGCAGCGTCCCAGGCAGCGGCACTGGCATCGGCACTGGC

CRISPR arrays and Neighbor proteins around NC_018828_4

CRISPR arrays

The CRISPR arrays of NC_018828_4

>merge|NC_018828|4|2259055-2259480|CRT
AGCGGCCCTGGCAGCGGCCCTGGCAGCGTCCCAGGCAGCGTCCCAGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGGCCCTGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGGCCCTGGCATCGGCACTGGCAGCGGCCCTGGCAGCGTCCCAGGCAGCGTCCCAGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGTACCAGGCAGCGTCCCAGGCAGCGTCCCAGGCAGCGGCCCAGGCAGCGTCCCAGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGTCCCAGGCAGCGTCCCAGGCAGCGGCACTGGCATCGGCACTGGCAGCGGCCCTGGCAGCGGC

>NC_018828|4|1|2259055-2259480|CRT
AGCGGCCCTGGCAGCGGC	CCTGGCAGCGTCCCAGGCAGCGTCCCAGGC
AGCGGCCCTGGCAGCGGC	ACTGGCAGCGGCCCTGGCAGCGGCCCTGGCAGCGGCCCTGGCAGCGGCACTGGC
AGCGGCCCTGGCATCGGC	ACTGGCAGCGGCCCTGGCAGCGTCCCAGGCAGCGTCCCAGGCAGCGGCCCTGGCAGCGGCACTGGC
AGCGGCCCTGGCAGCGGC	CCTGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGGCACTGGC
AGCGGCCCTGGCAGCGTA	CCAGGCAGCGTCCCAGGCAGCGTCCCAGGC
AGCGGCCCAGGCAGCGTC	CCAGGCAGCGGCACTGGC
AGCGGCCCTGGCAGCGTC	CCAGGCAGCGTCCCAGGCAGCGGCACTGGCATCGGCACTGGC
AGCGGCCCTGGCAGCGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018828.1|WP_010929852.1|2261267_2261909_-|hypothetical-protein	unknown	unknown	unknown
NC_018828.1|WP_080704133.1|2264194_2264443_+|Cro/Cl-family-transcriptional-regulator	unknown	unknown	gnl|CDD|374243
NC_018828.1|WP_015039657.1|2263699_2264152_-|phage-protein	unknown	unknown	gnl|CDD|374243
NC_018828.1|WP_033454823.1|2262002_2262998_-|hypothetical-protein	unknown	unknown	unknown
NC_018828.1|WP_015039430.1|2255556_2256060_-|hypothetical-protein	unknown	unknown	gnl|CDD|379158
NC_018828.1|WP_015039446.1|2266895_2267651_+|hypothetical-protein	unknown	unknown	gnl|CDD|288299
NC_018828.1|WP_010926418.1|2265142_2265397_-|hypothetical-protein	unknown	unknown	unknown
NC_018828.1|WP_015039654.1|2259908_2260898_-|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_018828.1|WP_164926388.1|2256049_2256430_-|hypothetical-protein	unknown	unknown	unknown
NC_018828.1|WP_015039432.1|2256548_2257196_-|YqaJ-viral-recombinase-family-protein	unknown	unknown	gnl|CDD|378216
NC_018828.1|WP_015039444.1|2265733_2266108_+|hypothetical-protein	unknown	unknown	unknown
NC_018828.1|WP_015039652.1|2253901_2254891_+|site-specific-integrase	unknown	unknown	gnl|CDD|271177
NC_018828.1|WP_010926410.1|2258182_2258365_-|hypothetical-protein	unknown	unknown	unknown
NC_018828.1|WP_164926532.1|2266104_2266896_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379352
NC_018828.1|WP_010926403.1|2254887_2255088_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|225848
NC_018828.1|WP_015039433.1|2257192_2258179_-|phage-related-DNA-recombination-protein	unknown	unknown	gnl|CDD|367688
NC_018828.1|WP_010926412.1|2258741_2258951_-|hypothetical-protein	unknown	unknown	unknown
NC_018828.1|WP_015039429.1|2255200_2255560_-|hypothetical-protein	unknown	unknown	unknown
NC_018828.1|WP_010926411.1|2258361_2258739_-|hypothetical-protein	unknown	unknown	unknown
NC_018828.1|WP_164926531.1|2264435_2265125_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018828.1|WP_080704133.1|2264194_2264443_+|Cro/Cl-family-transcriptional-regulator	gnl|CDD|374243	pfam15943, YdaS_antitoxin, Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT. YdaS_antitoxin is a family of putative bacterial antitoxins, neutralising the toxin YdaT, family pfam06254.	1.5083e-08
NC_018828.1|WP_015039432.1|2256548_2257196_-|YqaJ-viral-recombinase-family-protein	gnl|CDD|378216	pfam09588, YqaJ, YqaJ-like viral recombinase domain. This protein family is found in many different bacterial species but is of viral origin. The protein forms an oligomer and functions as a processive alkaline exonuclease that digests linear double-stranded DNA in a Mg(2+)-dependent reaction, It has a preference for 5'-phosphorylated DNA ends. It thus forms part of the two-component SynExo viral recombinase functional unit.	3.7708e-40
NC_018828.1|WP_164926532.1|2266104_2266896_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379352	pfam13730, HTH_36, Helix-turn-helix domain.	5.33337e-13
NC_018828.1|WP_015039657.1|2263699_2264152_-|phage-protein	gnl|CDD|374243	pfam15943, YdaS_antitoxin, Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT. YdaS_antitoxin is a family of putative bacterial antitoxins, neutralising the toxin YdaT, family pfam06254.	0.00252133
NC_018828.1|WP_015039652.1|2253901_2254891_+|site-specific-integrase	gnl|CDD|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.09448e-26
NC_018828.1|WP_010926403.1|2254887_2255088_-|helix-turn-helix-domain-containing-protein	gnl|CDD|225848	COG3311, AlpA, Predicted transcriptional regulator [Transcription].	7.40792e-06
NC_018828.1|WP_015039433.1|2257192_2258179_-|phage-related-DNA-recombination-protein	gnl|CDD|367688	pfam03837, RecT, RecT family. The DNA single-strand annealing proteins (SSAPs), such as RecT, Red-beta, ERF and Rad52, function in RecA-dependent and RecA-independent DNA recombination pathways. This family includes proteins related to RecT.	2.95737e-29
NC_018828.1|WP_015039446.1|2266895_2267651_+|hypothetical-protein	gnl|CDD|288299	pfam11417, Inhibitor_G39P, Loader and inhibitor of phage G40P. G39P inhibits the initiation of DNA replication by blocking G40P replicative helicase. G39P has a bipartite stricture consisting of a folded N-terminal domain and an unfolded C-terminal domain. The C terminal is essential for helicase interaction.	2.95544e-05
NC_018828.1|WP_015039430.1|2255556_2256060_-|hypothetical-protein	gnl|CDD|379158	pfam13392, HNH_3, HNH endonuclease. This is a zinc-binding loop of Fold group 7 as found in endo-deoxy-ribonucleases and HNH nucleases.	7.72426e-12
NC_018828.1|WP_015039654.1|2259908_2260898_-|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	3.40571e-30

Protein sequences

>NC_018828.1|WP_010926412.1|2258741_2258951_-|hypothetical-protein
MPGTGDTMETTYISDEQAVQVMAQLGGSFMKQLARLWMTADPLRRARLKEAFRDDFDRYRDMAARSDEA
>NC_018828.1|WP_010926411.1|2258361_2258739_-|hypothetical-protein
MLPLTYPTECGTAAVVRPLTDAERLAELRRDLDADLHYALVAQRCVRWPYGDPELVAEALYAATIGDAQSEAAFSLLVRAAARGESAVSVGTLFVEWTKLARARLLDTLVELTEDGQRVTFGSRQ
>NC_018828.1|WP_010926410.1|2258182_2258365_-|hypothetical-protein
MSRRLIAYLRATRLDLDLAGYAAMVAALAVATGLIGPTLDARSTLTACEGCGKTAVAAKE
>NC_018828.1|WP_015039433.1|2257192_2258179_-|phage-related-DNA-recombination-protein
MNNLAVITQDIYNARESFAAVLTDQSISFEKEAGFAIQVLQNNDYTLKVATGNRQSVINAVTNVAAIGISLNPAKRQAYLVPRDGRICLDISYMGLIDLAVATGSIRWAQAELVRSADTFALNGFDAPPTHVFNPFSKERGEIIGAYVVVKTADGDYLTTPMSRDEIDGIMNRSQSVKSGKSSPWKTDYGEMAKKTVVKRAYKYWPKNDRLSEAIHHLNTDGGEGLATTASAPVDPDLLPRLRKAVDAARDAAALEKVWKDGLAEVRATRDMAIYNAFKSAVAARGAVLRGEAVSIEPPPDDGKTIDEPPRDPSDDGFGRDDQGGIQE
>NC_018828.1|WP_015039432.1|2256548_2257196_-|YqaJ-viral-recombinase-family-protein
MNRYILSPHEQGSDGWLLDRCGRVTGSRAADMLAMTAKKEWSTKRADYKFELAIEVLTGMPQGSDYTSKEMQWGIDQEPFARMAYEEASGNVTIESGFMYLPDVAAGCSVDGLFVEDGRRGVLETKCPKSTTHIRYLEAGTLPDQYRPQCLHNVWVTGAEFADFVSFDPRFPQELQLFVCRFTPTAKELADHEKAVLQFLAERDELVAQLKRLAA
>NC_018828.1|WP_164926388.1|2256049_2256430_-|hypothetical-protein
MHFDSNTKKNDQPSATLQFTYRTSNDVLSEFSPDLKSSLYRRPRQDEGDMADNADPRLDDPGYLPCLKFPNMQNKVALSEKVVGATVTVHHGIGGKSDLNMDFRAMPFADNSFSLVARKEGDGNAN
>NC_018828.1|WP_015039430.1|2255556_2256060_-|hypothetical-protein
MRTDRELLELASLRSLLSYNPESGEFRWLKTNSNASVAGSVAGRSINSDGYKQIVIAGRFYKAHRLAWFYVHGEWPNQIDHINGIRTDNRLSNLRNVSAQHNTHNQRNPHKNNRSGFLGVVARPNGRYQAEIRVNGRKKFIGTFSTPEEASLAYVSAKREMHSGATL
>NC_018828.1|WP_015039429.1|2255200_2255560_-|hypothetical-protein
MTDLELLILSAKAAGIEVWPGTGFQAHMLFTRPAKADPHGKVAGIEWNPLTDDGDALRLAVKLRLWVHVDDYGGSARRPGDTWFGCAAHKYGGIEAATRRAIVRAAAEIGAKMQEAAHA
>NC_018828.1|WP_010926403.1|2254887_2255088_-|helix-turn-helix-domain-containing-protein
MEDRFITHTEIASLLQLNPAHVRDRLTKRKDFPRPFIFGGARRWKYSEVEDWIDGRRQAPDGRRAA
>NC_018828.1|WP_015039652.1|2253901_2254891_+|site-specific-integrase
MGTYRKRGDTWRAEINKAGVRESKTFPTKREAQEWAAARETELATIAVGGITPKSVAQVLQRYCDEISPRNKGHRWERVRIARFLKEEADLCAKLIHTISTADLGAWRDRRLAQVQPVSVRRDIALLRAAWGYARREWRNLKDDPWLDLTMPPEGRHRERIYTQDEVDRLVLALGWEEGQKVVTARQQTAVCFLLSLETAMRSGELLSLEHSQVDLKKRVAQLDQTKNGDRRAVPLSSRAVALFKSLAGLDDAKVFTITPALRDVYFRQGKAIAEVDGATFHDARATALTRLSKKLSILELARMVGHRDPRSLMIYYRESAADIAKKLD
>NC_018828.1|WP_015039654.1|2259908_2260898_-|pentapeptide-repeat-containing-protein
MNFEIKNRWTGAVLFTADVPDETESGMVARVALEQAVKSGANLARADLAGANLAGANLADAYLADADLAGANLARANLARANLARANLAGANLADAYLADADLAGANLARANLARANLAGANLADAYLARAYLADAYLADAYLADADLARANLACANLAGADLAGADLARANLAGANLAGAYLARANLAGARNLPVGTEATSPVEPYQRDTRPAAERNAARAARFRELNPTVPVVEALDAKILSAIENGRGGLEMGAWHTCETTHCRAGWAVHLAGEAGYALEREHGPQYAGRMIYMASVGRAPHFFASNELAMADLREQAAQQTKPVA
>NC_018828.1|WP_010929852.1|2261267_2261909_-|hypothetical-protein
MKPLLVAALSATALLVGCAAKQPQLTRSEYLKVTQRTYEGKSAEEVLNAAEKLFRLADGDDFKFFHDDDSMSASRSWIVYVVLAAAMGTDTWTVRTKEIPGGVRVSAALNTSAGSVLPMPTTGGDMSAGTTPGMGGNVPGTAIYDVFWARMDYLLGLSDQWMTCEESNRRVSTGAVWGPNDALCNGFNVKDDLPAELVGKIEKPKPSSTFNDG
>NC_018828.1|WP_033454823.1|2262002_2262998_-|hypothetical-protein
MAGEVVVLSTHEEALQFLQTLLDPDSSEDSLPEDIDIKGELASMLIEIEGTNYHSSVTGNLSRGLWELQQEIYRAVAATLHGAPNIKRLTKEELHDYNLVIDVEDGCSKLVADLKDIVGHLKDAVNSMESRHKLIFLVTTVVALTAGTGLTWIKNNEIAADKSVRVEQEKTAQMEVVRKAAQEVPALERWVQASENGARSIAKSVSDADSLSIGKESLNKHEIAEVNQRAAKEVSDIFKLTGYFRVTSITEPTADGVVRVGLSGNGEEFLAYMNLRDENNPIPDEKSNAVFLAPKHSKRVYMEVRVKKASDGIREAFIISLPDDPDANPKA
>NC_018828.1|WP_015039657.1|2263699_2264152_-|phage-protein
MSLLQIPIVSQWLSNVGMLIDDIRRTNLALLAKEAGGVGRLAEHLEKDQSQVSQWLNASKNSATGTPRGMRSATCRAIEEKMGKPPGWLDIDHAEDTSTSDAWPFPRLARADFEALTQPQKEAIEDWVISQVRAFGAMPAVKSDEAEKAA
>NC_018828.1|WP_080704133.1|2264194_2264443_+|Cro/Cl-family-transcriptional-regulator
MKLAEYLSEERGRQAALAKAIGAHAPDVSRWARGERPIPVEFGGPIEVATGGKCTRREHWPEDYARIWPELAAQAQQEVTHA
>NC_018828.1|WP_164926531.1|2264435_2265125_+|hypothetical-protein
MLNVLRRVFVPRPIRVEARPVHAGDDLILSVRDWPASQDMVGFLNATQQQFPGVRIHLLVGFDSVQVSGEQGSAQGEHATDERQPKLPIQQYRDEALSRGAKPGPQGNVVLLTWASAGRVVVVSVPPQEKGDAVEKFQASSPGVDQEGVGASDSTFGGDALWPANSGDVFHFAARQWLALKRPDLLAPDRYKQRVRCLAKKLRKAANAYLERSPHAGLATAAPAQQEAA
>NC_018828.1|WP_010926418.1|2265142_2265397_-|hypothetical-protein
MEEQELRHRLAVAEGNIAGLVAVIGALVRQLPEEQRLHLEARAEAMFEPLEAAMLGDADPYSDSSLAGLRNVRTMLSDLLSRSA
>NC_018828.1|WP_015039444.1|2265733_2266108_+|hypothetical-protein
MQREQGVGLDFLRIRPSEPMLFIDKAEIARCVTYRQAVRLAWDMRQPRGMTMRTLAELCGMYPQHVSSYLHEDPLLPSSFAKPSPSAFSIELMGWSLRTLSDIRDSLVGWALSFAQRCGRDVRS
>NC_018828.1|WP_164926532.1|2266104_2266896_+|helix-turn-helix-domain-containing-protein
MSYEVMKACRPLQMPSSPKAVLMALADYADEAGSAWPSIPTLCEYTCLSERTVHAAIKWLEQAKVVVADRANGRHTTYVVDANSFQQPPQQLRPRSSCTPANPAVTPAAAAVVPPQIPQSPPQQLRSNNQEQPREQPGTTNKRVREPKDSGFDAMKVDLPDWLPAESWERWVRHRVQLKKPITEETARQQIEDLGTFRGQGHQPDDVIRHCIGKSWQGLFPPKQGFGPRPAPAVSEADRRKQEFLRLAGHGGNDSRTIDMEQA
>NC_018828.1|WP_015039446.1|2266895_2267651_+|hypothetical-protein
MHSRDVSAFAELLAGVFDAYNRLPPQPATQLLWLRMLEPYEFPAVSAAFSQYVANEVKFPPTPAQILALLGHGTGDSRPTADEAWATALVSRDEAETVVWTLETAQAFAACRTVLDLGDEVGARMAFKGAYDRLVARARHDRQPVAWQVSLGWDPDRRERALTAAGTAGLLPAPHVAALLPPPDPSGGLGDDAVAAENIARLRKLLAGALSPSEKRRRAAEQAGQAERDRLDVLKAETAAKVAQHQQGVRA

Crispr_ID: NC_018828_5

• CRISPR_ID: NC_018828_5
• CRISPR_location: 3189247-3189343
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_018828_5

Consensus_repeat	Method
GTGCCTGTCCCGGCGGGGACAGGCACCC	CRISPRCasFinder

spacers of NC_018828_5

>5.1|3189275|41|NC_018828|CRISPRCasFinder
AGCCGCAGATGTCAGTCCCCATGCCGCTGGCGCATGACGGC

CRISPR arrays and Neighbor proteins around NC_018828_5

CRISPR arrays

The CRISPR arrays of NC_018828_5

>merge|NC_018828|5|3189247-3189343|CRISPRCasFinder
GTGCCTGTCCCGGCGGGGACAGGCACCCAGCCGCAGATGTCAGTCCCCATGCCGCTGGCGCATGACGGCGTGCCTGTCCCGGCGGGGACAGGCACCC

>NC_018828|5|4|3189247-3189343|CRISPRCasFinder
GTGCCTGTCCCGGCGGGGACAGGCACCC	AGCCGCAGATGTCAGTCCCCATGCCGCTGGCGCATGACGGC
GTGCCTGTCCCGGCGGGGACAGGCACCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018828.1|WP_015040095.1|3195694_3196714_-|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl|CDD|273137
NC_018828.1|WP_003810650.1|3176229_3177807_-|lipoprotein	unknown	unknown	gnl|CDD|274177
NC_018828.1|WP_015040098.1|3199182_3200109_-|ectoine-hydroxylase	unknown	unknown	gnl|CDD|131461
NC_018828.1|WP_015040088.1|3182933_3183764_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NC_018828.1|WP_003810617.1|3193339_3193708_-|aspartate-1-decarboxylase	unknown	unknown	gnl|CDD|180090
NC_018828.1|WP_003810623.1|3189441_3190779_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|182876
NC_018828.1|WP_015040093.1|3193838_3194711_-|MOSC-domain-containing-protein	unknown	unknown	gnl|CDD|225758
NC_018828.1|WP_165446311.1|3186465_3186765_-|hypothetical-protein	unknown	unknown	unknown
NC_018828.1|WP_015040091.1|3190783_3192040_-|D-amino-acid-dehydrogenase	unknown	unknown	gnl|CDD|234819
NC_018828.1|WP_015040092.1|3192235_3193282_-|CDP-6-deoxy-delta-3,4-glucoseen-reductase	unknown	unknown	gnl|CDD|181058
NC_018828.1|WP_003810637.1|3183781_3184726_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NC_018828.1|WP_015039079.1|3178687_3179908_+|ISL3-like-element-IS1001-family-transposase	unknown	unknown	gnl|CDD|225995
NC_018828.1|WP_015040089.1|3184778_3186353_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173867
NC_018828.1|WP_015040094.1|3194787_3195690_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NC_018828.1|WP_015040086.1|3174951_3176226_-|type-4b-pilus-protein-PilO2	unknown	unknown	gnl|CDD|369114
NC_018828.1|WP_015040096.1|3196710_3197910_-|four-carbon-acid-sugar-kinase-family-protein	unknown	unknown	gnl|CDD|377757
NC_018828.1|WP_003810643.1|3179954_3181310_-|amidase	unknown	unknown	gnl|CDD|223232
NC_018828.1|WP_015040087.1|3181306_3182941_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224048
NC_018828.1|WP_015040097.1|3197910_3198933_-|2-keto-3-deoxygluconate-permease	unknown	unknown	gnl|CDD|235384
NC_018828.1|WP_015040090.1|3188222_3189173_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176131

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018828.1|WP_003810623.1|3189441_3190779_-|extracellular-solute-binding-protein	gnl|CDD|182876	PRK10974, PRK10974, sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB.	1.31172e-74
NC_018828.1|WP_015040095.1|3195694_3196714_-|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl|CDD|273137	TIGR00557, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase. This model represents PdxA, an NAD+-dependent 4-hydroxythreonine 4-phosphate dehydrogenase (EC 1.1.1.262) active in pyridoxal phosphate biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine].	1.04152e-114
NC_018828.1|WP_015039079.1|3178687_3179908_+|ISL3-like-element-IS1001-family-transposase	gnl|CDD|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.88419e-80
NC_018828.1|WP_015040098.1|3199182_3200109_-|ectoine-hydroxylase	gnl|CDD|131461	TIGR02408, putative_L-proline_4-hydroxylase, ectoine hydroxylase. Both ectoine and hydroxyectoine are compatible solvents that serve as protectants against osmotic and thermal stresses. A number of genomes synthesize ectoine. This enzyme allows conversion of ectoine to hydroxyectoine, which may be more effective for some purposes, and is found in a subset of ectoine-producing organisms.	0
NC_018828.1|WP_015040088.1|3182933_3183764_-|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	6.72889e-86
NC_018828.1|WP_003810617.1|3193339_3193708_-|aspartate-1-decarboxylase	gnl|CDD|180090	PRK05449, PRK05449, aspartate alpha-decarboxylase; Provisional.	1.84176e-73
NC_018828.1|WP_015040089.1|3184778_3186353_-|ABC-transporter-substrate-binding-protein	gnl|CDD|173867	cd08502, PBP2_NikA_DppA_OppA_like_16, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NC_018828.1|WP_015040093.1|3193838_3194711_-|MOSC-domain-containing-protein	gnl|CDD|225758	COG3217, COG3217, Uncharacterized Fe-S protein [General function prediction only].	1.32862e-60
NC_018828.1|WP_015040092.1|3192235_3193282_-|CDP-6-deoxy-delta-3,4-glucoseen-reductase	gnl|CDD|181058	PRK07609, PRK07609, CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated.	0
NC_018828.1|WP_003810637.1|3183781_3184726_-|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.42336e-123
NC_018828.1|WP_003810650.1|3176229_3177807_-|lipoprotein	gnl|CDD|274177	TIGR02520, putative_Type_IV_pilus_protein, type IVB pilus formation outer membrane protein, R64 PilN family. Several related protein families encode outer membrane pore proteins for type II secretion, type III secretion, and type IV pilus formation. This protein family appears to encode a secretin for pilus formation, although it is quite different from PilQ. Members include the PilN lipoprotein of the plasmid R64 thin pilus, a type IV pilus. Scoring between the trusted and noise cutoffs are examples of bundle-forming pilus B (bfpB). [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking].	2.66535e-54
NC_018828.1|WP_015040097.1|3197910_3198933_-|2-keto-3-deoxygluconate-permease	gnl|CDD|235384	PRK05274, PRK05274, 2-keto-3-deoxygluconate permease; Provisional.	8.61552e-132
NC_018828.1|WP_015040094.1|3194787_3195690_-|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	3.77895e-54
NC_018828.1|WP_015040086.1|3174951_3176226_-|type-4b-pilus-protein-PilO2	gnl|CDD|369114	pfam06864, PAP_PilO, Pilin accessory protein (PilO). This family consists of several enterobacterial PilO proteins. The function of PilO is unknown although it has been suggested that it is a cytoplasmic protein in the absence of other Pil proteins, but PilO protein is translocated to the outer membrane in the presence of other Pil proteins. Alternatively, PilO protein may form a complex with other Pil protein(s). PilO has been predicted to function as a component of the pilin transport apparatus and thin-pilus basal body. This family does not seem to be related to pfam04350.	8.65547e-06
NC_018828.1|WP_015040096.1|3196710_3197910_-|four-carbon-acid-sugar-kinase-family-protein	gnl|CDD|377757	pfam07005, DUF1537, Putative sugar-binding N-terminal domain. This conserved region is found in proteins of unknown function in a range of Proteobacteria as well as the Gram-positive Oceanobacillus iheyensis. Structural analysis of the whole protein indicates the N- and C-termini interacting to produce an interacting surface into which a threonate-ADPcomplex is bound, suggesting that a sugar binding site is on the N-terminal domain here, and a nucleotide binding site is in the C-terminal domain (manuscript in preparation). There is a critical motif, DDXTG, at approximately residues 22-25.	7.88662e-55
NC_018828.1|WP_003810643.1|3179954_3181310_-|amidase	gnl|CDD|223232	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis].	6.98538e-115
NC_018828.1|WP_015040091.1|3190783_3192040_-|D-amino-acid-dehydrogenase	gnl|CDD|234819	PRK00711, PRK00711, D-amino acid dehydrogenase.	0
NC_018828.1|WP_015040087.1|3181306_3182941_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0
NC_018828.1|WP_015040090.1|3188222_3189173_+|LysR-family-transcriptional-regulator	gnl|CDD|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.82928e-67

Protein sequences

>NC_018828.1|WP_015040090.1|3188222_3189173_+|LysR-family-transcriptional-regulator
MRPQADLSTRQLRAFVMLADLRHFTKAAQACHLSQPAFSALIQSLEATLAMQLFDRSTRRVVLTQEGELFEPLARRLLADLGHAMTHIASFVELRRGRVHVAALPSLAAGWLPKVLHEFHAEHPDIELMLSDVLSDECIELVRSGQADFALASRGIRASDPAVLHARELCSDTFHLICRKDHPLTREPRLTLKHLAPWPFIHLTRNSSVRQTVEAALRPQVAKTILEVAQLATVAGMIEAGLGISVVPTFTLYQFERPGLLIRPISLPGLTRQIYIVRRQEERLSIAAQALYDLVVAKLGTPAAAKPRRRRTEKGR
>NC_018828.1|WP_165446311.1|3186465_3186765_-|hypothetical-protein
MPMSDVLVPLFRVAHARTGDKGDRSNISVIAWDRALYPLLVEQLTPEVVLAQFAHRRPAGAQRYLLPKLGAMNFVLDAVLDGGVNGALNLDAHGKALSY
>NC_018828.1|WP_015040089.1|3184778_3186353_-|ABC-transporter-substrate-binding-protein
MRYLKSTYAAVLLAIGTAVPHATTLAQEVKVAAEAPLRLLDPVGTTAYITRNHAYMVYDTLFALDAQLKPQPQMVSTWSVSPDKLVYRFTLRDGLKFHDGSPVTAADCVASIKRWAQRDLTGLRIMAAAKEITAKDDKTFEIVLEQPFGAVIEGLSKASSLPAFIMPKRIADAPASQAITEVIGSGPFRFVASEYRPGLRVVYERNTDYVPRSEPPSGLAGGKVVNVDRVVWLSLPDIQTEANALAKGEVDYVQTVYPDVVQTLEASKDVVIQKLANTTTPTLRLNWLQPPFNNQKVRQALLHAVSQRDYMDAQVGDPKAYRVCWAMFGCDSPLASTAGVVSQDDEADLNAAKALLKESGYKNEKAVLLHATDYPPTSAIAPFTAQILRSIGMKAEVQSMDWATFLTRRGKQDPVEKGGWSVAYGSWNTLDLMSPIANLNLDGRGKEGYAGWTESAEMESLRTQYAQATEPASRQQIAAKIQQLAYDQVFYIPLGTYSNYAARRSNVTPLLDAPVTVFWGISKN
>NC_018828.1|WP_003810637.1|3183781_3184726_-|ABC-transporter-permease
MQILRLLFLRLASAIPVVLVVVTVVFLLVRLTGDPATILAGDMASPEVVASVRADLGLDRPLLGQYAQWLWDLLQGNLGTSIVTKQPVATLIGERLESTLVLSLSALVVTVLLAVPLGVLAAWRHNTLVDRVVMIYAVIGFSLPSFVVGYLLILMFSVWLGWLPVQGYVSITDDIWLAAQHLVLPTLALAIFYMSLISRVTRASVLEVLNEDFVRTAKAKGVPPLRILSQHVLRNAAIPIVTVIGIGLAFLISGVVITESVFNLPGLGRLTIDAVLSRDYPVVQGVILFFACVYILVNLLIDMLYVVIDPRIRY
>NC_018828.1|WP_015040088.1|3182933_3183764_-|ABC-transporter-permease
MTSILRHNRLALLGGGVLLLMVAISVAASWIASTDPAMMQPRMRLTPPGEAFLLGTDALGRDVYSRVVHGSRMSLAIGALVVLITIAIGTLIGLVAGASRIMDRVLMRIMDGVMAIPGILLAVALVSLFGASLASVVIAIAVPEIPRVVRLVRSVVLSVREEPYVEAAVGLGVPYPKVVWRHILPNCFAPLIVQASYVFAAAILLEAVLGFLGVGFPPEIPTFGNILAEARPVFQRAPWATVAPGLLLAVTVLAVNLLGDGLRDSLDPKLARRAND
>NC_018828.1|WP_015040087.1|3181306_3182941_-|ABC-transporter-ATP-binding-protein
MTENTPKQRVLEVSGLAIRAGARTLVQDVTLSLAQGEILCLVGESGSGKSLTASAVMGLLPGNLGVGAGSIRLDGEDLTAASPARMQALRGDRMAMVFQEPMTSLNPLMRVGRQIAEVLQVHRPDLGAGQVRARVLELMGDVHLPTPEALMDAFPHQLSGGQRQRIMIAMALALEPALIIADEPTTALDVTTQAQVLKLFRQLLAKHSSAVLFITHDFDVVRDIADHVAVMQLGRIVEQGPAGQVLDAPRHDYTRKLLAAVPSGVPKTQQNASSDELLSVSGLNLVYESRGLLGPARRTHAVADVGFTLKKGETLGVVGESGSGKSTLGRCITRAHAPTSGRIVFDGVDIAGLSSKALRAVRRRVQMVFQDPYRSLNPRRRILHALIEGPIESGVDRKAACARAAELMALVGLPADGLQRYPHQFSGGQRQRICIARALAMEPDLIVADEAVSALDVSVQAQVLELFEDLQKRLGFAMIFITHDLRVAAQVCDRIGVMQKGRLLELGPVRQVIHAPQHPYTRHLFDSLPGRVGQAAEPAMELQA
>NC_018828.1|WP_003810643.1|3179954_3181310_-|amidase
MTSTDQHIARAGVAELARGIARGAFTPAEVTDVFLRRIQDLNPAIGAFVAVYEDEARHAARQATQALAQGQRLSPLHGIPFAVKDIVDVAGRFTTYGSRTGAGRQAGATAEYVRALLDAGMILLGKTHTVEFAFGGWGTNQRMGTPRNPLRADVPCATGGSSSGSGAAVGAQMVPFAVGTDTGGSIRIPSAFCGLTGMRPSMGRHSGAGVMSLSHTLDTIGPLARTVEDVQMLDDLLTGKTATDTAQPGSQAVARVRDARIGVLGAQWLGAIEPEVAHAYAQSLRAFEAMGATLVELALPFDREAFAQLTSTLIACEGLQFAGKYVHDPLSGMDEDVRARFLVGDRYDAAAYAELLGRRSAMIDTFTQAMAGVKALLMPTTPCVAQPLAGLEQSPYNPAVYTRMPAWLGCCALAVPNGSGAHGLPTSLQIVGLPESDRLVMSLGRAYQEYA
>NC_018828.1|WP_015039079.1|3178687_3179908_+|ISL3-like-element-IS1001-family-transposase
MLDRKLLESLGGWQGYGVERVEWPEDPGRTLSIYLKPTAKVMLCEQCGARCRQVHETTVRRVRDLPLFEYRVVLHVPRRRLWCEQCGGPRLERLAWLGRYQRVTDRLAQACSQLLQSSNVQAVARFFELGWHTVKTLDKARLRASVREPDWSKIEYLAMDEFALHKGHRYATVVVDPIGRQVLWIGPGRSRETARAFFEQLPPGAAQRIKAVAIDMTTAYELEIQAHSPQAEIVYDLFHVVAKYGREVIDRVRVDQANQLRQDRPARRIIKSSRWLLLRNRDNLDRQQAVRLDELLQANQPLLTVYVLRDELKRLWFYQRPAWARQAWNHWYEQAEQSGIPALNTFAQRLKGYLHGILARCRHPLNTSIVEGINNIIKVIKRRAYGYRDQEYFFLKIRAAFPGNAR
>NC_018828.1|WP_003810650.1|3176229_3177807_-|lipoprotein
MKARRLAMAGLSLALGGCSLSQQMQAMRDAATSLRARLLEGQQAVGRAGERPAREAAQDVARPWLAGRAQPLAREVLLPPALRADVDTTLLFAGKATLPVLAERLHRATGIAVRVHPDALLPRAAFLPRLAGPAELAAEPPAQAELRAGPRPLADTLDALAAQLYVHWRYHRGAIEFYRTETRVFDVRTLALAASAQARLGRAGSGETGSFDHASSTVLSADAGKALQAVRDRVAAFLTRAGVIAEIEAGGSTLAVTDTPEALARIEKYLQGENRALTRRVRLVFEELTVRTTAAAEGGIDWQAVYASARAAASYAMPGGAGAAGALGARVLAGPWRDARALIAALSTMGAVLRHRSIPMLTLNRRAVTHAVRTTFSYVDQVQRLSPTAAAPGGRDAVPGLAVQQKRETVGTFLTLLPEARDDGRILLSISYDNTIAQPLRTLTFGEGGQQVSLQQIAIDGSGIVQQVELLPGQPVILSGFDHSEDQYERHRLFPDAPLAAGGHDRTARERVTTVVMVTAQIDEG
>NC_018828.1|WP_015040086.1|3174951_3176226_-|type-4b-pilus-protein-PilO2
MRAATHPPLVLQQTQGGPMLAFGLTWFAVLGSHAALQGRARARALRATHYLVGGRHAVAAGCARLPRRYGALALHSAAQAYASLHPDGAQAGVASLPDGQGWLIAVQDGAVLASADRLFADVAQAQACLRTLLAQRPDLREVPAQAALDTLLARPDPSARLAPLASRWSRAPVAARAVALALAVAGGASLWRGLRQAPPPAAPDPRAVWRAAQAEFLRGWPVHTSSELARVLDTLQALPLRVAGWALRQAQCVPGPAWHCDADYHRVDAAATSLAFAAAVPPGWQMRLHTLEHTRVAWTLAGDQHGLDRTAPASPADTLALAATLQRASAAFTHVSVGAAQALAGPAWDGPPELAPPAAPELRRRELVLDGPLRSLALVWPLPAPIGWATVSLRVVPDAIATLRASVLSLHLQGSLYEQTTSRS
>NC_018828.1|WP_003810623.1|3189441_3190779_-|extracellular-solute-binding-protein
MKKLQMTGFARAMRASRRACVLGLAMAAMGVAQAADSVEIQVWHTLSGPNKAEFEKLAKQFNKEQGDVVVKLRDFGNQDDLKKEAVSAVKSKKGPNLVQLADNHSPEVVAEHKSILPLHQLLAKYPVKDLNWFLPSTTSFTRDGKGRLLAFPWMAEVPVMFYNTAYYKKAGLDPNKPARTWADLQAELLKLRDVANIDCPYATSDQVTVHLENLAPVNNQLYATLNNGLDVAKKGSPSMQFDTLYMRHVSLMVSWKRSLLLTAYSDDNKSDQLFAKGECAVLTTSSSALGQFLNTRSLSFGVAPLPYYDQVTKTGGRPFVSGSALWAMEGHPQAEEKATAKFLAWLSKPVIAAEWHQRTGYLPLTEAAFRASDVSFYNKVPGAQQLVELMRNPPAATSRGFRIANYERIEPVLNTQLTAAFDGKTPPVAALNNAASQARSLAAQR
>NC_018828.1|WP_015040091.1|3190783_3192040_-|D-amino-acid-dehydrogenase
MKVAVLGSGIIGVSSAWWLSQAGHDVVVVDRCTGAAQETSLANGAQISVSYAEPWANPQAPFKLLKWMFQDDAPLLFRLQLDWRQWQWGLAFLRECLPSRLAPNIRAMVRMAEYSRATLQGMRAELGIQYDHLERGILNFYRDQREFETSQRAAGLMRDFGVERRVINADEVVAIEPALAAHRQTIVGGDYTPEDESGDVHLFTAALVRRCEAAGVEFRFSTRVTRLLGEGGRVQGVELIEPDGRYGRLDADAFVVAMGSFSAQLVRPLGVPCMVYPAKGYSATFPVRPGALAPVVSLTDSSHKVVFSRLGERLRMAGTAELSGYSRGLNTGRCEAMTRLARELFPDALDFERVSYWSGLRPSTPSNVPLIGRTSVSNLYLNTGHGTLGWTMGVGSGRALADLLSGRRPEPEFPFLGL
>NC_018828.1|WP_015040092.1|3192235_3193282_-|CDP-6-deoxy-delta-3,4-glucoseen-reductase
MSFQVTIEPSKHQFQAEAGQTVLDAALAAGIVLPYSCRTGACSTCKGKVVAGEVDAGPYPAQILSPEDLAQGYTLFCQAKPQSDLVVESTEVRLASDIQIRKLPSRVQTIERVAPDVAVLKLQLPASEQFRYYAGQYIEVILKDGKRRSYSMAGAPHTGSPLELHIRHMPGGLFTDHVFGAGDTQMKEREILRLEGPFGSFFLREDSDKPIVLLASGTGFAPVKAIVEYMIHNQIQRPVVLYWGGRRPRDLYHDALAQSWAGSLPGFRYVPVISDALDEDGWSGRTGYVHEAVMQDLSDLSGYEVYACGTPLMVDAARREFSAQCGLPAEAFYADAFTSEADLAKATP
>NC_018828.1|WP_003810617.1|3193339_3193708_-|aspartate-1-decarboxylase
MQRIMLRAKLHRVTVTEADLHYEGSCGIDEDLLDAAGMREFERIELYNVTNGERFDTYIIKAARGSGAISLNGAAARRAQVGDLLIICTYGPMSEEQSATHKPQVVLVDDANRVKEIRKFPA
>NC_018828.1|WP_015040093.1|3193838_3194711_-|MOSC-domain-containing-protein
MSTRIRSLHIYPVKSCAGIDLAESIVDRAGLAHDRRWMVTTAAGQFMTQRQYPQMARIRTALEDGMLVLRAPGMEDLRIPADGSELAERTQPVGVWRDTVIARAEHPRSAEWLSRFLGLPCRLLKIDLRADRSANPEWVDTWLERHSEWAEDFAGDHFFGFADGFPLLVANQSSLDELNERLAARGQAPVPMNRFRANIVVEGDWPAFEEDQTACIVAGGVRMAFVKPCTRCPMPNVDQVTAEVYDEPGLTLTTFRSLEIGVVFGQNAIVDRTAPAPLRVGDAVEIELDF
>NC_018828.1|WP_015040094.1|3194787_3195690_-|GntR-family-transcriptional-regulator
MALSAIEPFALDRSGATPLHAQVADAIRNHIRDHRLTAGTVLPSEAALCHSFGVARSVVRQALGALVAEGLIRRDPGRAPVVAPPREHRRMVQRSAGLYEQFAGLGVALRTRVLACRPAEPPPKVAAFFGTTETLLLERLRSVDAQPLAYVRTWLPRAAIAGLAADHLQDASLHRVLAQRFGLRPGRGRNRIRAVAAEAALAQALDVAPGSPLLMLEGQGLDQDGHPLEWFTTWHRPENLVFDVDVGQERESVQPALTCGTAAVAPPAVAAPPSGALDAVEQSLLQALQAVRRARGDQQE
>NC_018828.1|WP_015040095.1|3195694_3196714_-|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MTQDATPSRIPTLAVTLGDVAGIGPEITAKMLLGHDELRQRARLLVVGDAAVLAQAVQAVGGDPARVRVIAKVIQAGPSLAHVPPGQLSAEAGDGSVRYVTTACALARDGLIDGIVTAPLNKAAMHMAGHKWPGHTELLAHEFGVKTFSLVLSAGDLYIFHATTHVSLRQAIEDVNPQRMRAVLRLAGSFARALGRADHPVAVAGLNPHAGENGIFGTEDAEILAPAVAQANAEGILAAGPIPADVLFLQAVRGKWKFVIACYHDQGHAPFKSVYGDDGVNITVGLPVVRVSVDHGTAFDIAGKGIAREDSLVLAAERAAQLAPGWHQVWETARSTTGG
>NC_018828.1|WP_015040096.1|3196710_3197910_-|four-carbon-acid-sugar-kinase-family-protein
MGGPYIGIVADDLTGSGDTAVQFVRAGWATQLSVGGAEQALADPAVRQAEVLAVTTHSRPLAAADAAAVVRGEVERLRAAGVQRLYKKVDSTLRGAFKAEIDAARLAWGEDAIAVVCPAFPVTGRTVRQGVLYVGDRPVTETSAATDPVTPVTESHIPTLLGCAQLAAQAGETPAELARRIAAAAPVVVVDALDDADVQRLARAIGVLGQRAVPVGSGGLAAPLARVWAGGQAAGPVLVVVTSQHSAARQQAAARTWAPTLAQLADDRNWAAWTAEVEAVEHGMPAVDALMLLAPEGRLAGLDADSVARRLGELAARLVLAHGAAGVVATGGDGASAVLAALQASGIALVDEVTGGVPLGTLTGGQAAGLPVVTKAGGFGEQDVLIRAAQAIGERRFTK
>NC_018828.1|WP_015040097.1|3197910_3198933_-|2-keto-3-deoxygluconate-permease
MTTEVSRVPFYTTMMKVPGGLMLLPLILGSLLGTFAPNALAIGGFTTALFKNSALPLIALLIFATGTQVNMRTGGPILATAGTILLMKTLVPATLIILLGHFVGLDGVLGISILAMLAAFDNSNGGLWLAYTGQYGDSRDRGAYVASAVNDGPFFSLLFLGASGLADIPTIALVAALVPFLLGVVVGNLDIEWRNVLKPVPNIVIPFFAFALGTGINLGAVISGGMSGLVLGLLISPITGALVYFGYRYILRRGGKSGLGFAAGTTAGNAIATPAVVAAADPSFQPYVATATAQVAACVLISSILAPVLASYFLKRAGELKPVEQEPQDERAGQPAEVSL
>NC_018828.1|WP_015040098.1|3199182_3200109_-|ectoine-hydroxylase
MISPAQDPYALRTDRSSAIIARQDPVVYGEGKFADALSADQVQSYERDGFLLLENLFSDEEVAALLAEVERMTRDPAIVRREEAITEPGSNAVRSIFMVHVLSPILGRLVRDPRLANAARQILGSEVYVHQSRANMKPGFKGKEFYWHSDFETWHVEDGMPSMRALSCSVLLTDNNETNGPLMLVPGSHRQFISCVGETPRDHYKQSLKKQEYGVPDPVSLQLLAEQGGISTMTGKAGSVVFFDCNTMHGSNSNISPWPRANVFMVYNSMENTLNPPTYGLNPRPEHIATRQAFKAVRPLDSLKLVER

Crispr_ID: NC_018828_6

• CRISPR_ID: NC_018828_6
• CRISPR_location: 3327794-3327869
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_018828_6

Consensus_repeat	Method
GCCTGTCCCGGCGGGGACAGATACC	CRISPRCasFinder

spacers of NC_018828_6

>6.1|3327819|26|NC_018828|CRISPRCasFinder
GTCTTGGCAGGCCAGCGGGACGGGGT

CRISPR arrays and Neighbor proteins around NC_018828_6

CRISPR arrays

The CRISPR arrays of NC_018828_6

>merge|NC_018828|6|3327794-3327869|CRISPRCasFinder
GCCTGTCCCGGCGGGGACAGATACCGTCTTGGCAGGCCAGCGGGACGGGGTGCCTGTCCCGGCGGGGACAGACACC

>NC_018828|6|5|3327794-3327869|CRISPRCasFinder
GCCTGTCCCGGCGGGGACAGATACC	GTCTTGGCAGGCCAGCGGGACGGGGT
GCCTGTCCCGGCGGGGACAGACACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018828.1|WP_003810363.1|3326926_3327637_-|hypothetical-protein	unknown	unknown	unknown
NC_018828.1|WP_003810346.1|3335402_3335864_-|holo-ACP-synthase	unknown	unknown	gnl|CDD|234610
NC_018828.1|WP_015040154.1|3338187_3341418_-|multidrug-efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|273335
NC_018828.1|WP_003810358.1|3330481_3331735_-|MFS-transporter	unknown	unknown	gnl|CDD|340883
NC_018828.1|WP_015040147.1|3320139_3321114_-|hypothetical-protein	unknown	unknown	gnl|CDD|319774
NC_018828.1|WP_015040153.1|3336691_3338191_-|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl|CDD|182103
NC_018828.1|WP_033449735.1|3332510_3334340_-|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl|CDD|234792
NC_018828.1|WP_015040149.1|3324396_3325833_+|dethiobiotin-synthase	unknown	unknown	gnl|CDD|379223
NC_018828.1|WP_003810375.1|3321178_3322453_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl|CDD|235656
NC_018828.1|WP_003810344.1|3335948_3336695_-|pyridoxine-5'-phosphate-synthase	unknown	unknown	gnl|CDD|235380
NC_018828.1|WP_003810356.1|3331898_3332471_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	unknown	unknown	gnl|CDD|182763
NC_018828.1|WP_164926592.1|3329653_3330475_+|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl|CDD|236986
NC_018828.1|WP_015040150.1|3325820_3326180_+|CidA/LrgA-family-protein	unknown	unknown	gnl|CDD|377131
NC_018828.1|WP_003810383.1|3317715_3318378_-|cytochrome-c-oxidase,-cbb3-type-subunit-II	unknown	unknown	gnl|CDD|237725
NC_018828.1|WP_015040152.1|3334302_3335364_-|beta-N-acetylhexosaminidase	unknown	unknown	gnl|CDD|235417
NC_018828.1|WP_033449714.1|3322556_3323750_+|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl|CDD|273303
NC_018828.1|WP_003810362.1|3328012_3329335_-|isocitrate-lyase	unknown	unknown	gnl|CDD|237893
NC_018828.1|WP_003810365.1|3326172_3326916_+|LrgB-family-protein	unknown	unknown	gnl|CDD|377236
NC_018828.1|WP_003810379.1|3319999_3320143_-|cbb3-type-cytochrome-oxidase-assembly-protein-CcoS	unknown	unknown	gnl|CDD|377073
NC_018828.1|WP_015040148.1|3323746_3324400_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|273783

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018828.1|WP_003810379.1|3319999_3320143_-|cbb3-type-cytochrome-oxidase-assembly-protein-CcoS	gnl|CDD|377073	pfam03597, FixS, Cytochrome oxidase maturation protein cbb3-type.	1.64467e-12
NC_018828.1|WP_003810346.1|3335402_3335864_-|holo-ACP-synthase	gnl|CDD|234610	PRK00070, acpS, 4'-phosphopantetheinyl transferase; Provisional.	1.59551e-52
NC_018828.1|WP_015040154.1|3338187_3341418_-|multidrug-efflux-RND-transporter-permease-subunit	gnl|CDD|273335	TIGR00915, Probable_aminoglycoside_efflux_pump, The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate].	0
NC_018828.1|WP_003810358.1|3330481_3331735_-|MFS-transporter	gnl|CDD|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.57397e-25
NC_018828.1|WP_015040147.1|3320139_3321114_-|hypothetical-protein	gnl|CDD|319774	cd02079, P-type_ATPase_HM, P-type heavy metal-transporting ATPase. Heavy metal-transporting ATPases (Type IB ATPases) transport heavy metal ions (Cu(+), Cu(2+), Zn(2+), Cd(2+), Co(2+), etc.) across biological membranes. These ATPases include mammalian copper-transporting ATPases, ATP7A and ATP7B, Bacillus subtilis CadA which transports cadmium, zinc and cobalt out of the cell, Bacillus subtilis ZosA/PfeT which transports copper, and perhaps also zinc and ferrous iron, Archaeoglobus fulgidus CopA and CopB, Staphylococcus aureus plasmid pI258 CadA, a cadmium-efflux ATPase, and Escherichia coli ZntA which is selective for Pb(2+), Zn(2+), and Cd(2+). The characteristic N-terminal heavy metal associated (HMA) domain of this group is essential for the binding of metal ions. This family belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	2.77314e-20
NC_018828.1|WP_033449735.1|3332510_3334340_-|excinuclease-ABC-subunit-UvrC	gnl|CDD|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
NC_018828.1|WP_015040149.1|3324396_3325833_+|dethiobiotin-synthase	gnl|CDD|379223	pfam13500, AAA_26, AAA domain. This domain is found in a number of proteins involved in cofactor biosynthesis such as dethiobiotin synthase and cobyric acid synthase. This domain contains a P-loop motif.	8.00351e-66
NC_018828.1|WP_003810375.1|3321178_3322453_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl|CDD|235656	PRK05964, PRK05964, adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional.	0
NC_018828.1|WP_003810344.1|3335948_3336695_-|pyridoxine-5'-phosphate-synthase	gnl|CDD|235380	PRK05265, PRK05265, pyridoxine 5'-phosphate synthase; Provisional.	5.79242e-145
NC_018828.1|WP_003810356.1|3331898_3332471_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	gnl|CDD|182763	PRK10832, PRK10832, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase.	3.46977e-48
NC_018828.1|WP_015040153.1|3336691_3338191_-|efflux-transporter-outer-membrane-subunit	gnl|CDD|182103	PRK09837, PRK09837, Cu(I)/Ag(I) efflux RND transporter outer membrane protein.	4.16308e-111
NC_018828.1|WP_015040150.1|3325820_3326180_+|CidA/LrgA-family-protein	gnl|CDD|377131	pfam03788, LrgA, LrgA family. This family is uncharacterized. It contains the protein LrgA that has been hypothesized to export murein hydrolases.	1.3896e-24
NC_018828.1|WP_003810383.1|3317715_3318378_-|cytochrome-c-oxidase,-cbb3-type-subunit-II	gnl|CDD|237725	PRK14487, PRK14487, cbb3-type cytochrome c oxidase subunit II; Provisional.	1.50334e-135
NC_018828.1|WP_015040152.1|3334302_3335364_-|beta-N-acetylhexosaminidase	gnl|CDD|235417	PRK05337, PRK05337, beta-hexosaminidase; Provisional.	0
NC_018828.1|WP_033449714.1|3322556_3323750_+|8-amino-7-oxononanoate-synthase	gnl|CDD|273303	TIGR00858, Putative_8-amino-7-oxononanoate_synthase, 8-amino-7-oxononanoate synthase. 7-keto-8-aminopelargonic acid synthetase is an alternate name. This model represents 8-amino-7-oxononanoate synthase, the BioF protein of biotin biosynthesis. This model is based on a careful phylogenetic analysis to separate members of this family from 2-amino-3-ketobutyrate and other related pyridoxal phosphate-dependent enzymes. In several species, including Staphylococcus and Coxiella, a candidate 8-amino-7-oxononanoate synthase is confirmed by location in the midst of a biotin biosynthesis operon but scores below the trusted cutoff of this model. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	1.2202e-142
NC_018828.1|WP_003810362.1|3328012_3329335_-|isocitrate-lyase	gnl|CDD|237893	PRK15063, PRK15063, isocitrate lyase; Provisional.	0
NC_018828.1|WP_003810365.1|3326172_3326916_+|LrgB-family-protein	gnl|CDD|377236	pfam04172, LrgB, LrgB-like family. The two products of the lrgAB operon are potential membrane proteins, and LrgA and LrgB are both thought to control of murein hydrolase activity and penicillin tolerance.	1.36587e-69
NC_018828.1|WP_164926592.1|3329653_3330475_+|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl|CDD|236986	PRK11792, queF, 7-cyano-7-deazaguanine reductase; Provisional.	0
NC_018828.1|WP_015040148.1|3323746_3324400_+|alpha/beta-hydrolase	gnl|CDD|273783	TIGR01738, Pimeloyl-_methyl_ester_esterase, pimelyl-[acyl-carrier protein] methyl ester esterase. This CoA-binding enzyme is required for the production of pimeloyl-coenzyme A, the substrate of the BioF protein early in the biosynthesis of biotin. Its exact function is unknown, but is proposed in ref 2. This enzyme belongs to the alpha/beta hydrolase fold family (pfam00561). Members of this family are restricted to the Proteobacteria. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	7.27607e-07

Protein sequences

>NC_018828.1|WP_003810363.1|3326926_3327637_-|hypothetical-protein
MALVLARFGFGFCMLLAALVLLAAATLLATRLVGWAVRAFALERSQALASGVAIFILVALALWGCHAVGEVLYGAIGATALVGGAPHWLAGNSHVSAAALMGATTAAAMLAGGPAFWRWLRARRAAAAEQPAPRKAAPPKGAKPAARAAKAAAKTQIAPRGQRIPWLGWTAFFLLFIGAAVLAFAYIVAPIEAGASGLRLEHATRARPVYLAGLTLLGGGAFFLLAWLSRRRPPGD
>NC_018828.1|WP_003810365.1|3326172_3326916_+|LrgB-family-protein
MPDFVNLWIYLSSTPLFGLTATLTVYLSAHAMYLRLGQVPLANPVLWSMVVLAAGLLAFGVPYPTYFAGAQFIHFLLGPAVVALAWPLWMRRAELRRRWARLLWAALFGGAVACASAVLLGWAVGLPRDIILSLAPKSVTAPVAMGLSETLGGIPALSAVFAALTGLVGALTGKYLFDLLGPVRGRQDWADRGFALGTVSHGIGAARAIQVNADAGAYAGLALGLQVILASLLIPVAFRLAAGLGGS
>NC_018828.1|WP_015040150.1|3325820_3326180_+|CidA/LrgA-family-protein
MQALTGFTWLLALQALGEAGSRLLHFPIPGPVTGMLLLLVALRWPLVREPVALAAQFLLSHLSLLFVPVGVGVMTHIALLAEYGLRMAAVIALSTLAGMAATYWALRVGRSAAPETDDA
>NC_018828.1|WP_015040149.1|3324396_3325833_+|dethiobiotin-synthase
MSTRSTPTIGQRFDRAAARYETHAEVQRHAAEQLAERIAALPLPAEPRILEIGCGTGLLTRALARRLGRADWTITDIAPAMLAAQQAGPPPAGRVRHQLVDGEHPAGLPGGYDLICSSLAVQWFGDLDAGLARLAGLLAPGGLLAIATLAEHTFSEWRAAHQAHGLHAATPAYPPAERIGRTLAGLRGGITREAYRQRHPDALHFVRSLKAIGASAPAAGHAPLSPAAFRRVLAQFDRQGNHVTYDLAYGLWRKQAPGVFVTGTDTGVGKTLASAILARAWRAHYWKPLQTGVAEEPGDTETVAALAGLEPARLHPPAHVLQAPLSPWAAAPLEGVTLDAAAIAPPQVDGPLVVEGAGGLYVPIDERHMMIDLMARLGMPVVLAARSGLGTINHTLLSLHALRERRLPVLGVIMLGEPSAGNRHAIEHFGSVPVLAQIPRLARVDAEAVEAWAARIPPLADCLARRWPDTQETPACRP
>NC_018828.1|WP_015040148.1|3323746_3324400_+|alpha/beta-hydrolase
MSAPRPLLRFEHGWAHDAGVWAPLRAALTDWPQQAADAGYFGPAVEPPPDGAPVVAIGHSLGFLKILQSPAPGCIAYIAINGFARFAGGADYPPGVAPRLLERMLARLELDPAAVVDDFRRRAGSAPHAGTPRPEPLRHDLRRLREADERQTLAASRLPLLALAGTADPIVAPALTRAQFGACAGLRWRDGGGHLLPTSDPDWCAGRIRAFLAGLPA
>NC_018828.1|WP_033449714.1|3322556_3323750_+|8-amino-7-oxononanoate-synthase
MSKLDSLFTAALEQAAQRQVRRRLRRATAAPPGRLALDGRTLVNFSSNDYLGLARHPLLAERASLWATRHGAGAQASRLVCGNLDLHEQVEAKLARLKGTEAALLLASGWQANAAVLPALFKAAAAQGEPQVYTDRLNHASLHHGCQAAGVRQIRFRHNDLAHLEHLLAERAGAPGARFIVTESVFSMDGDRADVPALAALAARHHAFLYLDEAHATGVLGPRGMGLAGLAPGGVDLAMGTFSKGLGSFGAYVAGSRALCDYLVNACSGFIYTTALPPAVLGAIDAALDLVPRLDQARAALLGHGERLRASLAAQGIDCGASSTQIVPAIVGDAGHALALAAELERRGLLAVAIRPPTVPAGTSRLRIALSAAHGEAELDQLIEALAAGWRAVRQAA
>NC_018828.1|WP_003810375.1|3321178_3322453_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MSDTTPAWMAQGYPHIWLPYAQMKTAAPPLPVVRSHGSLLELADGRTLIDGVASWWTACHGYNHPHIAQAVREQLDRMPHVMFGGLAHEPALNLASRLSALLGPGLERVFYTDSGSVAVEVAMKMAVQFWLNQGERGRTRFVAFRGGYHGDTFGTMAVCDPDEGMHAMFRGLLPEHDVLALPRDEAALAALQAHLERHAGRIAGMLVEPLVQGAGGMLLHDPQVLARLRELADRYGILLIFDEIFTGFGRTGTMFAFEQAGVRPDIVTLSKALTGGTLPLAATVASARVFEGFWSDDPGHALMHGPTFMGCALACAAANASLDLFEREPRLRQVAALEQALRAGLEPCRDLPWVRDVRVLGAIGVIELDGIGARDDLRRRLVDAGVWVRPFGNIVYLTPAFTIAEDELQALLAAVRQVVAERRP
>NC_018828.1|WP_015040147.1|3320139_3321114_-|hypothetical-protein
MRPTSILAVPADLPGADRQVRCHALVRLGVAWLAMMQVMMFAWPGYVRNDGIPADALATLDWAIVLMNWAALLMTVPVVLYCAWPIWRGAASGLRRGRAGMDAPVALGIVAAFVPSVHATWTGRGEVYFDSVTMFVAFLLTARYLELCARQACGASALATPLVRRLHQAGGELGAAADRLATRFVFVQVALALAAGAAWTQIDAAHAVPVMVALLVMSCPCAMSMAVPSAMACAHSALLARPEATAAQGDALLAAAARVARQNLYGSLAWHLLMTPLALAGWVAPWLAAITMLLSSLAVAGNAWRLLRHRWDAAPAAAVAQPAP
>NC_018828.1|WP_003810379.1|3319999_3320143_-|cbb3-type-cytochrome-oxidase-assembly-protein-CcoS
MSILYLLLPLSLAFVLAIGVALWWAVFSGQYDDTEDQGAAILRDNDN
>NC_018828.1|WP_003810383.1|3317715_3318378_-|cytochrome-c-oxidase,-cbb3-type-subunit-II
MAQKQHGFFSHQTLEKNIGLMIIASILVVSVAGLVQIIPLFFQHSTTQAMPGVEPYEPLQLMGRDVYIREGCVGCHSQQVRTLQAEVQRYGPYSVAGESVFDHPFLWGSKRTGPDLARVGERYSDEWHRIHLRDPRAVVPESNMPAYPWLQHADLTGQNVAQRMQALRRLGVPYTDEAIAAAPAAIAGKTEEDALVAYLQALGVGARRGAASEPQRAAGG
>NC_018828.1|WP_003810362.1|3328012_3329335_-|isocitrate-lyase
MSNRETEIRNLQKDWAENTRWQGIKRAYSAEDVIRLRGSVAVEHSLARRGATRLWDSLHSEPFVNSLGALTGNQAMQQVKAGLKAIYLSGWQVAGDANLAGEMYPDQSLYPANSVPQVVRRINNALARCDQIQWMEGKNPGDQDYIDYYAPIVADAEAGFGGVLNAFELMKAMIEAGAAGVHFEDQLASVKKCGHMGGKVLVPTREAVSKLVSARLAADVMGTPTILLARTDADAADLVTSDVDENDRPFITGERTVEGFFRTRAGLDQAISRGLAYAPYADLIWCETSTPNLEYARKFAEAVHRQFPGKLLAYNCSPSFNWKKNLDDGTIAKFQRELGAMGYKFQFITLAGFHALNYGMFELAHGYARRQMSAFVELQQKEFAAAELGFTAVKHQREVGTGYFDAVTQTIEGGQSSTTALTGSTEEAQFEHGGQAVKAA
>NC_018828.1|WP_164926592.1|3329653_3330475_+|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MSLSNAPLGQHVAYPSQYDPGLLFPIPRATNRASLQLGATLPFTGVDLWNAYELSWLDARGKPRVAMATFSFPADSPNIVESKSFKLYLNSFNQTRLPNAQALRDRLERDLAAAAGAPVGLEFISPQRFGELNMAELDGIYIDKLDIEIDTYEPAPQLLQCAPGDEVEETLATRLLKSNCPVTDQPDWASLQVRYRGRPIDRAALLKYVVSFRQHAEFHEHCVERIFGDIMRACQPRQLTVYARYTRRGGLDINPWRSNFESAPPADVRTARQ
>NC_018828.1|WP_003810358.1|3330481_3331735_-|MFS-transporter
MAMNSETAVLDSPALRRRDWQIILLIGVAHSSSHFFQLVLPSLYVSLGTEFGLDFARLGLLVSVFYVVSGLGQASSGFVVDRIGARPVLWFGLACFVLSAVLIGAASGYAMLMLAAAIGGIGNSVFHPADYSIINHRVSPPRLGHAFSLHGLTGNLGWALTPVFITTITLLASWRVAAFSAAALVAVVLLMTVIGRDLLGGAAPAEAGGKSAARPAAQESVWQTLAALLARPALWGAFLFFACTSIALSSVQNYTIPLLGQLYDLSKVAASSALSGYMVASALGMAAGGFLVSANPRTELTVTAALIMAGLTLVVLAMGWVPAGWAALVVGLAGFCSGVAAPSRDMLIRRVTPKGATGSVYGLVYSGMDVGSALGPLGFGLLLDAGMAHGPWVGAGVAFAAAALLAQWIAMQARRTA
>NC_018828.1|WP_003810356.1|3331898_3332471_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase
MPINVPIFLTWLRIAMIPLVVGLFYLPESWMSVPMRDTFAAWAFIIAALTDWFDGWLARRWNQTSAFGAFLDPVADKLMVCAALIVLLDLSRVDAFISLIIIGREITISALREWMAKIGASASVAVHRLGKFKTAAQMVAIPCLLYDQPLFGLSSRLIGDVLIVVAAVLTVWSMLYYLQRAWPAIREKSQ
>NC_018828.1|WP_033449735.1|3332510_3334340_-|excinuclease-ABC-subunit-UvrC
MPDDFNLKSFLADLPHLPGVYRHLDAAGEVMYVGKARDLKKRVSSYFQKNLASPRIAQMVAKVASVDVTVTRSEAEALLLENNLIKSLRPRYNILFRDDKSYPYLLITGHAWPRIAYYRGATSKRGQYFGPYPNSWAVRETIQILQKVFRLRTCEDTVFANRSRPCLLHQIGRCSAPCVGVIEAGDYAHDVQRAVRFLNGEAREVMDEIEARMLQASTELRFEEAAVLRDQMGSLSKVLHQQTMENVGGDDTDVIAVASAGGKICVNLAMVRGGRHLGDKPFFPTHAEGEQPAQVLEAFVAQHYADGAMPPVLVCSHALPDSGLVGLLAEQGGTRAARVLTRPQGVRRSWLEQAQKNAEMALARALTESGARAGRTLALAEALDLDTDEESLDALRIECFDISHTAGEATQASCVVFLHHDMQPSLYRRYNIVGITPGDDYAAMRQVLTRRFGKVADGEAPMPGLVLIDGGKGQVEVARQVFVELGLDIQSLVGVAKGEGRKVGLETLVFADGRPPVALGKESAALMLIAQVRDEAHRFAITGMRARRAKTRNVSRLEEIEGIGARRRQRLLARFGGLSGVSSASIEDLASVEGISQELAVRIYDALHG
>NC_018828.1|WP_015040152.1|3334302_3335364_-|beta-N-acetylhexosaminidase
MSSKKKTKPVLPPGPVMVDVAGTTLTKDEKRRLRNPLVGGVILFARNFTDRRQLCALTRAIHKARKEPLLIAVDHEGGRVQRFRDDGFTALPPMQELGKLWDRDPLAAMRLATEAGYVLAAELRACGVDLSFTPVLDLDYGVSKVIGNRAFHHDARVVTMLSRALAQGLALAGMAACGKHFPGHGFVGADSHQEIPVDPRPLARILKDDAAPYAWLGDLVMPAVMPAHVIYPKVDAQPAGFSRRWVSEILRERLGYDGVVFSDDLTMEGASVAGDILARAEAALGAGCDMVLVCNRPDLADELLDRLQVQHPAASVERIRRLMPRFAAPDWDTLQNDSRYQHARRLQSQIVSG
>NC_018828.1|WP_003810346.1|3335402_3335864_-|holo-ACP-synthase
MSSVSAAGATPPASPGCIAGIGMDLLRIERIERALARHGDRFAQKILGPEELAKFHARRRRDPARGVRFLATRFAAKEAFSKAIGLGMRMPMSWRRVQTLNAPGGRPVLVIGAELADWFDARFGAAHVSITDESDMAAAYVIVERKPAPDGRP
>NC_018828.1|WP_003810344.1|3335948_3336695_-|pyridoxine-5'-phosphate-synthase
MIELGVNIDHVATLRQQRHTAYPDPVQAALRAEDAGADLITLHLREDRRHIQDADVYAIRPLLRTRMNLECAVTPEMLEIACAVKPSDVCLVPEKRTELTTEGGLDVAGAQAAVTDAVQLLAEAGIRVSLFIDPDARQIEAAARAGAPVIELHTGAYAEARDDAAVQAELARVRAAVAEGLRHGLRVNAGHGLHYGNVQAVAALDGIAELNIGHAIVAQSIFDGWDKAVRDMKALMVQARLAAVRGHA
>NC_018828.1|WP_015040153.1|3336691_3338191_-|efflux-transporter-outer-membrane-subunit
MMAVMYKRSALSVLVAAALAGCSLAPDYKRPEAPVQANWPDQPKVQYGAYASPTSLGEQPAAAVAPQGATPADEIGWREFFRDARLQKLIELALVNNRDLRVAVQRVEEARVQYGVQRGAQWPSIGAGIQGQRQHLPPDMRPLGPDSTSISSQYQAGLGLTTFEIDLFGRLRNLSEAAYQQYLSTEQAQRSVHITLVGAVAQSYFNLRAAEVQLELTQKTLASRQESYNLVKTRFDGGVASELDLNQSKSLLDSAFADLAALARARAQAANALVVLVGLPGLPEDLPAPAVFGRDQLLASVPAGLPSDLLTRRPDILAAENQLKAANANIGAARAAFFPTISLTGLLGVASPSLDNLFKGGQGYWSFSPSITTPLFAGGSIREGLNLAKARDNIAVAQYEQSIQQAFREVSDALAGEATYSAQLDAQRALQVAAGRTLELSNLRYNNGIDSYLQVQTAQVDFFNAQLGLVQTGLAALINRVELYKALGGGWQESTTKQP
>NC_018828.1|WP_015040154.1|3338187_3341418_-|multidrug-efflux-RND-transporter-permease-subunit
MPQFFIDRPIFAWVVALFILLTGILAIPNMPVSQYPDVAPPAITITATYPGASAKEVAESVTSIIEDQLNGAKGLLYYESVSDSYGQSQITATFAPGTDPDLAQVDVQNRVSNVTAQLPVAVMQQGLQYEQTSAGFLMIVTLSSTDGTLDQTALADYITRNVKNPVSRVPGVGQFQLFAAPRAMRIWVDPDKLVGFNLSMAEVNQAISQQNVLISAGSIGAPPNPDSQRVTATVIVNGQLSTIEGFGQIVLRANTDGSKVLLRDVARIEVGADNYQFGARLNGKPTAAFAIVLSPDANALATAEGVRQQMASLSQYFPSNIRYDIPYDTAPYVKVSIEQVIHTLVEAMVLVFLVMFLFLQNVRYTLIPALVVPVAMLGAFAVMLALGFSINVLTMFAMVLAIGILVDDAIVVVENVERIMATEGLSPKEATKKAMPQISGAIVGITLVLVTVFLPLAFMTGSVGVIYRQFSVAMAVSIFFSAFLALSFTPALCATILKPIPKGHHQEKKGFFGWFNRKFDATTHNYQNWVSRILHKGGRMMLAFALLVVLLGWLYMRLPSSFLPEEDQGYVVSNIELPTGASANRTIEVIEEVENYFRNIPAVENVITVQGYSFNGNGLNAAIAFTTLKDFSERKSRADSAGAIAFTVFSKQLMGIHDAQVFTLVPPAISSLGNASGFDFRLQDRGGAGTEALGAATAELMGMAAKSPVLSQVRITGLGPGSQLSLTIDRDKAAALGVNFDEAATLISTAVGSAFLNKFPNMGRMQNIWVQADQQYRMQVEDLLKLNARNNQGGMVPLSTFVSAKWVQGPVQVVRYNSYESVRIGGDAAAGYTTGEAMQEMQDLVARLPPGFGYEWNGLSYQERLAGNQAPILMGLALLVVFLVLAALYESWAIPLSVMLVVPLGMLGAVALVTVLGMSNDVYFQVGMVTVIGLAAKNAILIVEFAKDQYARGQGLYESAMEAARLRFRPILMTSLAFILGVVPLAIATGAGAASQRAVGIGVLGGMLAATPFAVIFVPTFFVVVLGLFKTRPRLLGAELRAFEEEQAAKRAAEQQQPQDGAATPAPQTGGQENKE

Crispr_ID: NC_018828_7

• CRISPR_ID: NC_018828_7
• CRISPR_location: 4158443-4158536
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_018828_7

Consensus_repeat	Method
GTGCCTGTCCCCGCCGGGACAGGCAC	CRISPRCasFinder

spacers of NC_018828_7

>7.1|4158469|42|NC_018828|CRISPRCasFinder
CCGGGCCCAGGAACCCCCCCACGCTGCGCCCGCTGTGCGGGC

CRISPR arrays and Neighbor proteins around NC_018828_7

CRISPR arrays

The CRISPR arrays of NC_018828_7

>merge|NC_018828|7|4158443-4158536|CRISPRCasFinder
GTGCCTGTCCCCGCCGGGACAGGCACCCGGGCCCAGGAACCCCCCCACGCTGCGCCCGCTGTGCGGGCGTGCCTGTCCCCGCCGGGACAGGCAC

>NC_018828|7|6|4158443-4158536|CRISPRCasFinder
GTGCCTGTCCCCGCCGGGACAGGCAC	CCGGGCCCAGGAACCCCCCCACGCTGCGCCCGCTGTGCGGGC
GTGCCTGTCCCCGCCGGGACAGGCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018828.1|WP_015040494.1|4162529_4163444_+|DMT-family-transporter	unknown	unknown	gnl|CDD|307170
NC_018828.1|WP_015040496.1|4164189_4165092_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|378820
NC_018828.1|WP_165446316.1|4165549_4166551_-|ChbG/HpnK-family-deacetylase	unknown	unknown	gnl|CDD|212118
NC_018828.1|WP_042962164.1|4166485_4166881_+|GtrA-family-protein	unknown	unknown	gnl|CDD|377229
NC_018828.1|WP_015040491.1|4154707_4155463_-|TerC-family-protein	unknown	unknown	gnl|CDD|223930
NC_018828.1|WP_003814699.1|4156088_4158212_-|elongation-factor-G	unknown	unknown	gnl|CDD|234569
NC_018828.1|WP_015040489.1|4148122_4149151_-|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl|CDD|366103
NC_018828.1|WP_015040492.1|4155573_4156092_+|MgtC/SapB-family-protein	unknown	unknown	gnl|CDD|224204
NC_018828.1|WP_015040488.1|4145306_4146941_+|AMP-binding-protein	unknown	unknown	gnl|CDD|341257
NC_018828.1|WP_003814681.1|4150475_4151453_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176106
NC_018828.1|WP_003814711.1|4165097_4165553_-|multidrug/biocide-efflux-PACE-transporter	unknown	unknown	gnl|CDD|226610
NC_018828.1|WP_003814701.1|4159937_4160408_-|universal-stress-protein	unknown	unknown	gnl|CDD|366180
NC_018828.1|WP_015040490.1|4151463_4152435_-|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270234
NC_018828.1|WP_003814689.1|4152501_4153287_-|crotonase/enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl|CDD|181723
NC_018828.1|WP_015040495.1|4163440_4164100_+|LysE-family-translocator	unknown	unknown	gnl|CDD|224199
NC_018828.1|WP_015039524.1|4158654_4159875_+|ISL3-like-element-IS1001-family-transposase	unknown	unknown	gnl|CDD|225995
NC_018828.1|WP_041937294.1|4149177_4150350_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173841
NC_018828.1|WP_003820700.1|4160496_4160841_-|TIGR01244-family-phosphatase	unknown	unknown	gnl|CDD|225984
NC_018828.1|WP_003814691.1|4153279_4154512_-|CoA-transferase	unknown	unknown	gnl|CDD|367110
NC_018828.1|WP_164926629.1|4160940_4162386_-|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl|CDD|224089

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018828.1|WP_015040494.1|4162529_4163444_+|DMT-family-transporter	gnl|CDD|307170	pfam00892, EamA, EamA-like transporter family. This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.	2.95196e-09
NC_018828.1|WP_015040496.1|4164189_4165092_+|alpha/beta-fold-hydrolase	gnl|CDD|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	3.18988e-19
NC_018828.1|WP_165446316.1|4165549_4166551_-|ChbG/HpnK-family-deacetylase	gnl|CDD|212118	cd10807, YdjC_like_3, uncharacterized YdjC-like family proteins from bacteria. This subfamily contains many hypothetical proteins, and belongs to the YdjC-like family of uncharacterized proteins from bacteria. The YdjC-family is represented by an uncharacterised protein YdjC (also known as ChbG) encoded by the chb (N,N'-diacetylchitobiose, also called [GlcNAc]2) or cel operon in Escherichia coli, which encodes enzymes involved in growth on an N,N'-diacetylchitobiose carbon source. The molecular function of this subfamily is unclear.	4.0804e-92
NC_018828.1|WP_042962164.1|4166485_4166881_+|GtrA-family-protein	gnl|CDD|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	8.84202e-15
NC_018828.1|WP_015040491.1|4154707_4155463_-|TerC-family-protein	gnl|CDD|223930	COG0861, TerC, Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism].	1.10858e-77
NC_018828.1|WP_003814699.1|4156088_4158212_-|elongation-factor-G	gnl|CDD|234569	PRK00007, PRK00007, elongation factor G; Reviewed.	0
NC_018828.1|WP_015040489.1|4148122_4149151_-|acyl-CoA/acyl-ACP-dehydrogenase	gnl|CDD|366103	pfam00441, Acyl-CoA_dh_1, Acyl-CoA dehydrogenase, C-terminal domain. C-terminal domain of Acyl-CoA dehydrogenase is an all-alpha, four helical up-and-down bundle.	2.30059e-12
NC_018828.1|WP_015040492.1|4155573_4156092_+|MgtC/SapB-family-protein	gnl|CDD|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	5.92748e-44
NC_018828.1|WP_015040488.1|4145306_4146941_+|AMP-binding-protein	gnl|CDD|341257	cd05934, FACL_DitJ_like, Uncharacterized subfamily of fatty acid CoA ligase (FACL). Fatty acyl-CoA ligases catalyze the ATP-dependent activation of fatty acids in a two-step reaction. The carboxylate substrate first reacts with ATP to form an acyl-adenylate intermediate, which then reacts with CoA to produce an acyl-CoA ester. This is a required step before free fatty acids can participate in most catabolic and anabolic reactions. Members of this family include DitJ from Pseudomonas and similar proteins.	1.60742e-168
NC_018828.1|WP_003814681.1|4150475_4151453_+|LysR-family-transcriptional-regulator	gnl|CDD|176106	cd08414, PBP2_LTTR_aromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LTTRs involved in degradation of aromatic compounds, such as CbnR, BenM, CatM, ClcR and TfdR, as well as that of other transcriptional regulators clustered together in phylogenetic trees, including XapR, HcaR, MprR, IlvR, BudR, AlsR, LysR, and OccR. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	2.33368e-60
NC_018828.1|WP_003814711.1|4165097_4165553_-|multidrug/biocide-efflux-PACE-transporter	gnl|CDD|226610	COG4125, COG4125, Predicted membrane protein [Function unknown].	2.35069e-54
NC_018828.1|WP_003814701.1|4159937_4160408_-|universal-stress-protein	gnl|CDD|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	9.38587e-30
NC_018828.1|WP_015040490.1|4151463_4152435_-|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl|CDD|270234	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) proteins present in a number of bacterial species, but mainly in proteobacteria. In eubacteria, at least three families of periplasmic binding-protein dependent transporters are known: the ATP-binding cassette (ABC) transporters, the tripartite ATP-independent periplasmic transporters, and the tripartite tricarboxylate transporters (TTT). Bug proteins are the PBP components of the TTT. Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	1.92114e-117
NC_018828.1|WP_003814689.1|4152501_4153287_-|crotonase/enoyl-CoA-hydratase-family-protein	gnl|CDD|181723	PRK09245, PRK09245, crotonase/enoyl-CoA hydratase family protein.	2.06175e-156
NC_018828.1|WP_015040495.1|4163440_4164100_+|LysE-family-translocator	gnl|CDD|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	1.30492e-31
NC_018828.1|WP_015039524.1|4158654_4159875_+|ISL3-like-element-IS1001-family-transposase	gnl|CDD|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.48605e-80
NC_018828.1|WP_041937294.1|4149177_4150350_-|acyl-CoA-dehydrogenase	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	3.96966e-84
NC_018828.1|WP_003820700.1|4160496_4160841_-|TIGR01244-family-phosphatase	gnl|CDD|225984	COG3453, COG3453, Uncharacterized protein conserved in bacteria [Function unknown].	3.40043e-35
NC_018828.1|WP_003814691.1|4153279_4154512_-|CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	8.36236e-118
NC_018828.1|WP_164926629.1|4160940_4162386_-|PLP-dependent-aminotransferase-family-protein	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.93727e-110

Protein sequences

>NC_018828.1|WP_003814699.1|4156088_4158212_-|elongation-factor-G
MTRRTSIERYRNIGISAHIDAGKTTTTERILFYTGITHKLGEVHEGAATMDWMEQEQERGITITSAATTAFWRGMAGNYPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYDSVGGVQPQSETVWRQANKYGVPRIAFVNKMDRVGADFFRVQRQIVERLKGDAVPIQIPVGAEDHFEGVVDLVKMKAIIWDDASQGVRFEYRDIPPELQAQAEQWREKMIEKAAEANEALLEKYLSGQPLSEDEIKSGLRARTVANEIVPMLCGSAFKNKGVQAMLDAVIDYLPSPADVPAIIGHDERDREIERHPADDEPFSALAFKIMTDPFVGQLVFFRVYSGVVKSGDSVLNPLKSKKERLGRILQMHANERREISEVYAGDIAAAVGIKEITTGDTLTDPAHVIILERMTFPEPVISQAVEPRTKADQEKMGIALNRLAQEDPSFRVRTDEESGQTIISGMGELHLEILVDRMKREFGVEANVGKPQVAYRETIRSTVTDVEGKFVKQSGGRGQYGHVVLKLEPQEQGKGYEFVDAIKGGVVPREFIPAVDRGVRETLNTGVLAGYPVVDVKVTLVFGSYHDVDSNENAFRMAASMAFKEGMRRAKPVLLEPMMHVEVETPEDFTGNVMGDLSSRRGMVQGMEDIAGGGGKLVRAEVPLAEMFGYSTSLRSLTQGRATYSMEFKHYAEAPRQVAEQIIAARGSGAAARG
>NC_018828.1|WP_015040492.1|4155573_4156092_+|MgtC/SapB-family-protein
MDTVWMEIWTTVRNEFADIPDVAEATRIVLRLGMAVALGGLLGYERKRSGKAAGLRTHMLVALGAALFVLVPLQGGMEVGDLSRVLQGVIAGIGFLGAGAIIKLGNEGEIRGLTTSAGIWLTAAIGVAAGMGREATALASTLIALFVLAALRRLEKRIAARDDKRVVAQPPP
>NC_018828.1|WP_015040491.1|4154707_4155463_-|TerC-family-protein
MDYLVSLAQQPAAWAALATLIAMEVVLGIDNLIFISILTNKLPPQHQTKARRIGIGMALILRLALLGTVAFIVQLTQPVFELFGHGFSWRDVILVAGGLFLVWKATKEIHHHVDPNPGDDMFGGKAATLGFAAAVAQILMLDLVFSIDSIITAVGMTEHILIMFVAVIVAVAVMLLAAEPLARFIERNPTVVMLALAFLMMIGMTLIAEGFGAHVPKGYIYAAMAFSALVEGLNMMARRAREGRGAGAAGG
>NC_018828.1|WP_003814691.1|4153279_4154512_-|CoA-transferase
MSGPLEGVRILDVTTVLMGPYATQILGDLGADVIKVEPPAGDNVRGIGPGRHADMGGIFLHANRSKRSIALDLKNPAGREALLKVAATCDVLVYNVRPQAMARLGLSYAEVAQANPSILYVGMYGYDQRGPYAARAAYDDLIQGAVGIPSLSVEAGSDIPRYAPSAMVDRIVGISAANAVTAGLYHRARTGQGQAIDVPMFETMAHLILGDHMMGQTFEPPLGPPGYPRILNADRRPYATRNGHICVLLYADKHWKAFFELIGQPGRDAADPRFRDIGTRTQHIHAIYRLVSDAIASRTTEEWLAAFEAADIPAMPVHTMASLLRDPHLEAIGFFGMVDHPSEGAVRMMAVPSRWSGTPPQPRGHAPRLGEHSVDVLKEAGYDDEAIAALVRNGAAIAAARQLPEGTDHD
>NC_018828.1|WP_003814689.1|4152501_4153287_-|crotonase/enoyl-CoA-hydratase-family-protein
MTDFLRHERHGGVLLLTMDRERTRNALSDADAVEALVQACARIGADLSVRAVVLTGSHGVFSSGGNLKTLSDTVGAGLGEPVHSRQAYRSGIQRIPLALYNLEVPTIAAVNGPAIGAGCDLACMCDIRLAARQASFAESFVKLGLTPGDGGAWLLPRIVGMSRACELAFTGRSIDAARARELGLVSEVFDADALLPAALALAQEIAQHSGHALRLTKRLLREGQHTRLDTLLELSAGFQALAHHTQEHAGALDAHLSRKRG
>NC_018828.1|WP_015040490.1|4151463_4152435_-|tripartite-tricarboxylate-transporter-substrate-binding-protein
MHSRTLALALLSVAALAQGGSARAASDYPAHPVKIIVSLPPGSGADTTARFLSKHLAERFKQPFVVENRPGGNSFIAAQAVATAPPDGYTLFVASNSPMTTNAAVFKNLPYDAVKDFAPVAPIARFPMALVVPANSPYRSVADLVAAARAAPGQLNFASGTATYQVVLELFHEQNGIKATHVPYKGTSAALADVAGGVVQYSVADVSAALPLIRGGKLRPLAVTSTRRIKDLPDVPTMQESGNKGFEAYAWTAVFFPAKVDPAIVARVSDAVQALVRSQEGKAFMEQLGGEPFVGGPDTLAAFQRDELASMRCIAKLANIQQE
>NC_018828.1|WP_003814681.1|4150475_4151453_+|LysR-family-transcriptional-regulator
MWTGQYIVHIASPAHHWRRAVELRQLKQLLVLSETLNFHRAAERLHMAQPPLSTAIKKLEQELGVQLFERLPAGLQPTPAAEVVLRYARATLFYADEIQRAAQEGASGKQGMLKVGFVGSSIYSLMPQLLSAFRKDYPRVDLVIEESTTVDLLRRLDAHTLDVALVRFPVLEPSTARITLLQADHLMLAVPAGSRYAQRDDVALDELADEPFIGYSRTHVPGMHALIMYAFQQYGVVPHIAQEAIQVQTILSLVESGLGLAIVPKVACRQAGSGVRLVNVPQLAETIKVGIALAVHPDNATPTTANFVDMACRLMQTEPAAGQAR
>NC_018828.1|WP_041937294.1|4149177_4150350_-|acyl-CoA-dehydrogenase
MGAILGTIIEALQLAAIPAHDEALRPAVRAFLDEALREMPADRRARSWMGHDAEFSRALARQGWLGLTLPVEYGGAGRSNFARFVLSEELLAAGAPVSAHWIADRQTAPLILRFGSPAQRAFYLPRIIRGEAFFAIGMSEPDTGSDLASVRTRATPVADGWLLNGRKIWTTNAHRSHYMCALVRTSGASEDRHRGLSQMIFDLALPGIEIRPIRDIAGDAHFCEVLFDNVLLPHDALVGEEGSGWRQVMAELALERSGPERIYSSMVLLDGWLAHLRRDAAPQRAQVCLAGRLAARLAVLRSMSLAVSQRLEQGADASLAAVLVKDLGTEFEQAVPELIGQALHASPQPAPDDVLMRTLAYLTLINPTFSLRGGTRHILRGIIARELGLR
>NC_018828.1|WP_015040489.1|4148122_4149151_-|acyl-CoA/acyl-ACP-dehydrogenase
MVSTMQQDLYETFARALAGLCPLERVRELEAAADPRAGAARAWNEVDALGYGDALSPAEHGGAGLSLADAEGLLRAAGAMALPFPFADTLLARALLRAAGQAVPDGPIALGVALPHGAGWRCAPIAGVALAQAVAVEHDGCLALWPAPDAVQPGLFRPRASGAPAWRGTPAQAGRAGAPAGAVQAWRNAADAAGMAGAMQAVLDRCVAYVQERQQFGRALGRFQAVQQDISMLAEQVAAVAMAARLACASGALFPDPTLAACARLRACEAVPVVCALAHAVHGAIGITEELPLGLYTARLHEWRATGMSEDDCAELLGRRVLADGERTLLDVVRGMVSAAHA
>NC_018828.1|WP_015040488.1|4145306_4146941_+|AMP-binding-protein
MADFTLDDIKQRSMAEITAMQARRHGEKTFLHFLPRDERISYAGFDRRSSAVGRGLKAHGVQAGAHVGLILDNCPEMILAVFALAKIGAVWVPINTAAKGKLLVYYLDFADITTLIVHEKYLALIAACLHELPRLQRIVVVDDGSGHAAQQAPRAIRYAALEQDGREDQAFDADPWQLGALLFTSGTTGPSKAVMWPQAGVNVWAAQNAMARWVAHDDVEYVCLPLFHANALLNSTWTAFVAGATVALTDRYSTTRFWSEIRQCGATRFNSLGAIVNFLWTQPPTPQDRDHKVRLCSMAPVPPYVHEFEARFGVKVFTGYGLSDYCLAASTRLDDPAEKAFSCGKPRPGIDLRIVDDNDIELPAGQTGEIALRSHETWSTASGYYKMPEATLQARRNFLFHTGDRGYLDADGYLYFVDRKKDSIRRRGENISSQEVEAVLMSHPEVVNAAVYPVRGDLPEDEVGASVLLRPGSALSYQDLTRYCVENMSYYMVPRFLEFVDALPLTESGKIEKFKLKQRTEQRPSPLWDREAAGIVVSRASARA
>NC_018828.1|WP_015039524.1|4158654_4159875_+|ISL3-like-element-IS1001-family-transposase
MLDRKLLESLGGWQGYGVERVEWPEDPGRTLSIYLKPTAKVMLCEQCGARCRQVHETTVRRVRDLPLFEYRVVLHVPRRRLWCEQCGGPRLERLAWLGRYQRVTDRLAQACSQLLQSSNVQAVARFFELGWHTVKTLDKARLRASVREPDWSKIEYLAMDEFALHKGHRYATVVVDPIGRQVLWIGPGRSRETARAFFEQLPPGAAQRIKAVAIDMTTAYELEIQAHSPQAEIVYDLFHVVAKYGREVIDRVRVDQANQLRQDRPARRIIKSSRWLLLRNRDNLDRQQAVRLDELLQANQPLLTVYVLRDELKRLWFYQRPAWARQAWNHWYEQAEQSGIPALNTFAQRLKGYLHGILARCRHPLNTSIVEGINNTIKVIKRRAYGYRDQEYFFLKIRAAFPGNAR
>NC_018828.1|WP_003814701.1|4159937_4160408_-|universal-stress-protein
MFKKILIPTDGSPLSAQAANAGICFARSTGAEVVALHVTQPFAATIGFDGMAAAYAITDEDYEKASAEQAEKYLKLILDRAETAGVKAESRAVSNFNVADGIVQAAGEAGCDLIFIGSHGRSGLSRLLLGSVTAKVLSLAHTAVLVYRVKEDKDKK
>NC_018828.1|WP_003820700.1|4160496_4160841_-|TIGR01244-family-phosphatase
MSAAIKPLTENFAVAPQLGPADMADVAAAGYKSVIINRPDFEGGPDQPTAADVSQAAQALGLQVEYQPVVGSAMTAADVARFAELLRTMPGPVLAYCRTGTRCTNLFAAAQQLG
>NC_018828.1|WP_164926629.1|4160940_4162386_-|PLP-dependent-aminotransferase-family-protein
MTVATSSPSGAGWQPVRQADATLVTQLADDLARRIDEHGLRPGTRLPSIRRMAEQSGVSRFTVVEAYDRLVARGLVQSRRGAGFFVRARSASLTALASARVPQAAPETPVRVDVSWLLRNMFRETAAGMPGGAGLLPPEWLDPDMVAAAVRAVGRTVRGNLVSYGSPQGYAQLRQQLASMLQADGVPAHPERNLLTTNGVTHGLDIVARHLIKPGDTVLVEDPAWFVIFGRLAAFGARPVGVPRGPDGPDLAMLDRLAAEHKPRLYIINGAVHNPTGHTLSAGAAYDILRLAERHDFMVVEDDTYADLHPGGAMKLAALDRLERVILVGGFSKMLAASLRVGYIAAGAETLQRLTDLKMLAGLTSPELGERVVHRVLVEGQYRRHIERVRARVNEARLRSIQALQQLGLSVPHEPHAGMFVWADCGRDSEPVARNAAERGMLLAPGTLFSPSGAPSTMLRFSVAMVDTPGIWQSIAAVMAQ
>NC_018828.1|WP_015040494.1|4162529_4163444_+|DMT-family-transporter
MSPPSAQASAPSASPHAPSWEGYGYGLIGVLVFALTLPMTRLAVGELSPLLVGLGRALLAAVPAAALLWLTRSRRPDRAEWSGIVLAAVGIVVGWPVASTLAMASVPAAHGAVFNGLLPLSTAVFAAWRSGERPSPAFWSFAVLGAVLVAGYALLQGHGALQPGDLWLLLAVVLGGMGYAEGARASRTLGGWRTICWALVVSVPALLPAVLWLAHDAAWPSLPVAGAFAYLAFGSMFLGFFAWYRGLAIGGIARVGQIQLLQPFLTVVAAALLFNEQVEPITYVFAVAVVLVIAGGRRAMVRKA
>NC_018828.1|WP_015040495.1|4163440_4164100_+|LysE-family-translocator
MIGSDLSSLDQAPLASLSVLMPLVLFTLVNSLTPGPNNVMLASSGLTFGFRRTIPHLLGISVGFSIMLLMVGLGLGATLERLPWLYSTLKYGGTAYLLYLAWKIATSGPMESGAERGKPLTFIQAALFQWVNPKAWVMIVSVVATYTPQHGYFANLIIATLVCGVVNLPSVGVWAAFGMALRRWLHRPAAVRAFNVGMAVLLVVSLYPVSLDLLALYTG
>NC_018828.1|WP_015040496.1|4164189_4165092_+|alpha/beta-fold-hydrolase
MVSLPFRLSWRRMAAVLLLAAGALGFNQLDAWQRQAIFSPQTDQQRWWREPPAGTEVFDLALPNGDKVHAWYWQSPRRDAPTVLYLHGARWNLNGSAFRMEGWTRMGYSMLAIDYRGFGQSTPLLPSEQSASQDAAAALQELARRFIYGHSLGGAIAIDLAARPDLPPFAGLIVESSFTSIGAMLGTMKWGWVPGATLLVTQPFASVDKLAALTTPMLLLHGTADRVVPHTMSDELYRAAQQVPADLKRLVKIEGASHSGAIRSGRIYEDAVANFVRDAGRGYAGRQGAPTPLTASRPGT
>NC_018828.1|WP_003814711.1|4165097_4165553_-|multidrug/biocide-efflux-PACE-transporter
MSSSSKQTPKTIKERFLHAFFFEIIAIGLSAPVAAWAMDQPLFDMGVLTAVIAWIALLWNMVYNAGFERLERRFGVVRTMPVRVAHAVGFELGLVLIIVPLAAWWLAISFWEAFMLDIGLLMFYLPYAFFYNLAYDKLRARWWGRIEPAGA
>NC_018828.1|WP_165446316.1|4165549_4166551_-|ChbG/HpnK-family-deacetylase
MGGGRGAADGNEPGNLSQQAAHVEEVSPLRNQAGDVRCRRIAVCGDDFGMNEAIDGALIELAGAGRLSAVSCMPLAPAFAADAPALARLDVDLGVHVDFTEAFAGAAPAAPGLAALLWRAYAGQLDPDWIDARLASQFDAFERAFGRAPDYVDGHQHVHQLPGILPRLRALLKRRYAGQRIWLRHTAPGLQFGLPLAEAAKARLIGALGAGALARAAGQEGWQTNRRMLGVYGFTGGPRRYAGLLHHWLMNARDGDLLMCHPGWPQVHGAAHASQRAAEYEVLAHPELGTWLARNGLRIVRLSQVRGRQASQESGKVRNVPHSGSFRRLASRL
>NC_018828.1|WP_042962164.1|4166485_4166881_+|GtrA-family-protein
MRGLLRQIAWFIAVGCAAAATHWAVAVACVEWAGLPPLGANVVGWLLAFVVSFTGHFRLTFRHLAASWTIAARRFFLVSALGFAINELSYAWLLHATSLPYDVLLALVLIGLAFLTFVASRLWAFRHRHAP

Crispr_ID: NC_018828_8

• CRISPR_ID: NC_018828_8
• CRISPR_location: 4427579-4427662
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_018828_8

Consensus_repeat	Method
GGTGCCTGTCCCCGCGGGGACAG	CRISPRCasFinder

spacers of NC_018828_8

>8.1|4427602|38|NC_018828|CRISPRCasFinder
ATACCGTCTTGGCCGTCAAGCGTTCTGGCGTATGACGG

CRISPR arrays and Neighbor proteins around NC_018828_8

CRISPR arrays

The CRISPR arrays of NC_018828_8

>merge|NC_018828|8|4427579-4427662|CRISPRCasFinder
GGTGCCTGTCCCCGCGGGGACAGATACCGTCTTGGCCGTCAAGCGTTCTGGCGTATGACGGGGTGCCTGTCCCCGCGGGGACAG

>NC_018828|8|7|4427579-4427662|CRISPRCasFinder
GGTGCCTGTCCCCGCGGGGACAG	ATACCGTCTTGGCCGTCAAGCGTTCTGGCGTATGACGG
GGTGCCTGTCCCCGCGGGGACAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018828.1|WP_003815201.1|4434928_4436881_-|penicillin-binding-protein-2	unknown	unknown	gnl|CDD|274573
NC_018828.1|WP_003815198.1|4433795_4434932_-|rod-shape-determining-protein-RodA	unknown	unknown	gnl|CDD|274033
NC_018828.1|WP_033446211.1|4425738_4426332_+|phosphoheptose-isomerase	unknown	unknown	gnl|CDD|237567
NC_018828.1|WP_003815185.1|4423622_4424195_-|methylated-DNA--[protein]-cysteine-S-methyltransferase	unknown	unknown	gnl|CDD|223427
NC_018828.1|WP_015040604.1|4427674_4428463_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|224381
NC_018828.1|WP_003815180.1|4418580_4419507_+|HPr-kinase/phosphorylase	unknown	unknown	gnl|CDD|235459
NC_018828.1|WP_033446463.1|4420882_4421497_-|c-type-cytochrome	unknown	unknown	gnl|CDD|225418
NC_018828.1|WP_015040605.1|4431210_4432704_+|DASS-family-sodium-coupled-anion-symporter	unknown	unknown	gnl|CDD|279307
NC_018828.1|WP_003815190.1|4426328_4427072_+|BON-domain-containing-protein	unknown	unknown	gnl|CDD|182907
NC_018828.1|WP_015040603.1|4425196_4425730_+|YraN-family-protein	unknown	unknown	gnl|CDD|173148
NC_018828.1|WP_003815191.1|4427068_4427560_+|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl|CDD|239264
NC_018828.1|WP_003815186.1|4424191_4425130_-|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	unknown	unknown	gnl|CDD|223390
NC_018828.1|WP_003815184.1|4422675_4423626_+|septal-ring-lytic-transglycosylase-RlpA-family-protein	unknown	unknown	gnl|CDD|223868
NC_018828.1|WP_003815194.1|4429626_4430373_+|pyrimidine-5'-nucleotidase	unknown	unknown	gnl|CDD|319791
NC_018828.1|WP_003815203.1|4437444_4438329_-|rod-shape-determining-protein-MreC	unknown	unknown	gnl|CDD|237560
NC_018828.1|WP_015040606.1|4432714_4433770_+|Ldh-family-oxidoreductase	unknown	unknown	gnl|CDD|376860
NC_018828.1|WP_010927138.1|4430422_4430998_+|nucleoid-occlusion-factor-SlmA	unknown	unknown	gnl|CDD|181894
NC_018828.1|WP_015040607.1|4436894_4437458_-|rod-shape-determining-protein-MreD	unknown	unknown	gnl|CDD|274574
NC_018828.1|WP_003815183.1|4421806_4422679_+|RNase-adapter-RapZ	unknown	unknown	gnl|CDD|235450
NC_018828.1|WP_003815193.1|4428724_4429627_+|acetylglutamate-kinase	unknown	unknown	gnl|CDD|234869

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018828.1|WP_003815201.1|4434928_4436881_-|penicillin-binding-protein-2	gnl|CDD|274573	TIGR03423, pbp2_mrdA, penicillin-binding protein 2. Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NC_018828.1|WP_003815198.1|4433795_4434932_-|rod-shape-determining-protein-RodA	gnl|CDD|274033	TIGR02210, Rod_shape-determining_protein_RodA, rod shape-determining protein RodA. This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	3.23854e-160
NC_018828.1|WP_033446211.1|4425738_4426332_+|phosphoheptose-isomerase	gnl|CDD|237567	PRK13936, PRK13936, phosphoheptose isomerase; Provisional.	6.68272e-126
NC_018828.1|WP_003815185.1|4423622_4424195_-|methylated-DNA--[protein]-cysteine-S-methyltransferase	gnl|CDD|223427	COG0350, Ada, Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair].	7.98182e-54
NC_018828.1|WP_015040604.1|4427674_4428463_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl|CDD|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	1.35473e-135
NC_018828.1|WP_003815180.1|4418580_4419507_+|HPr-kinase/phosphorylase	gnl|CDD|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	5.69016e-145
NC_018828.1|WP_033446463.1|4420882_4421497_-|c-type-cytochrome	gnl|CDD|225418	COG2863, COG2863, Cytochrome c553 [Energy production and conversion].	1.97897e-12
NC_018828.1|WP_015040605.1|4431210_4432704_+|DASS-family-sodium-coupled-anion-symporter	gnl|CDD|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	5.99556e-115
NC_018828.1|WP_003815190.1|4426328_4427072_+|BON-domain-containing-protein	gnl|CDD|182907	PRK11023, PRK11023, divisome-associated lipoprotein YraP.	1.20064e-42
NC_018828.1|WP_015040603.1|4425196_4425730_+|YraN-family-protein	gnl|CDD|173148	PRK14685, PRK14685, hypothetical protein; Provisional.	4.38701e-89
NC_018828.1|WP_003815191.1|4427068_4427560_+|TlpA-family-protein-disulfide-reductase	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.58284e-41
NC_018828.1|WP_003815186.1|4424191_4425130_-|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	gnl|CDD|223390	COG0313, COG0313, Predicted methyltransferases [General function prediction only].	9.54075e-109
NC_018828.1|WP_003815184.1|4422675_4423626_+|septal-ring-lytic-transglycosylase-RlpA-family-protein	gnl|CDD|223868	COG0797, RlpA, Lipoproteins [Cell envelope biogenesis, outer membrane].	3.79567e-55
NC_018828.1|WP_003815194.1|4429626_4430373_+|pyrimidine-5'-nucleotidase	gnl|CDD|319791	cd02604, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to Saccharomyces cerevisiae Phm8p and Sdt1p. This family includes Saccharomyces cerevisiae Phm8p (phosphate metabolism protein 8) and Sdt1p (Suppressor of disruption of TFIIS). Phm8p participates in the ribose salvage pathway, it catalyzes the dephosphorylation of nucleotide monophosphates to nucleosides, its preferred substrates are nucleotide monophosphates AMP, GMP, CMP, and UMP. Phm8p is also a lysophosphatidic acid phosphatase, dephosphorylating lysophosphatidic acids (LPAs) to monoacylglycerol in response to phosphate starvation. Sdt1p is a pyrimidine and pyridine-specific 5'-nucleotidase; it is an NMN/NaMN 5'-nucleotidases involved in the production of nicotinamide riboside and nicotinic acid riboside, and is a pyrimidine 5'-nucleotidase with high specificity for UMP and CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.14842e-46
NC_018828.1|WP_003815203.1|4437444_4438329_-|rod-shape-determining-protein-MreC	gnl|CDD|237560	PRK13922, PRK13922, rod shape-determining protein MreC; Provisional.	9.0892e-90
NC_018828.1|WP_015040606.1|4432714_4433770_+|Ldh-family-oxidoreductase	gnl|CDD|376860	pfam02615, Ldh_2, Malate/L-lactate dehydrogenase. This family consists of bacterial and archaeal Malate/L-lactate dehydrogenase. L-lactate dehydrogenase, EC:1.1.1.27, catalyzes the reaction (S)-lactate + NAD(+) <=> pyruvate + NADH. Malate dehydrogenase, EC:1.1.1.37 and EC:1.1.1.82, catalyzes the reactions: (S)-malate + NAD(+) <=> oxaloacetate + NADH, and (S)-malate + NADP(+) <=> oxaloacetate + NADPH respectively.	8.30087e-126
NC_018828.1|WP_010927138.1|4430422_4430998_+|nucleoid-occlusion-factor-SlmA	gnl|CDD|181894	PRK09480, slmA, division inhibitor protein; Provisional.	1.59741e-107
NC_018828.1|WP_015040607.1|4436894_4437458_-|rod-shape-determining-protein-MreD	gnl|CDD|274574	TIGR03426, shape_MreD, rod shape-determining protein MreD. Members of this protein family are the MreD protein of bacterial cell shape determination. Most rod-shaped bacteria depend on MreB and RodA to achieve either a rod shape or some other non-spherical morphology such as coil or stalk formation. MreD is encoded in an operon with MreB, and often with RodA and PBP-2 as well. It is highly hydrophobic (therefore somewhat low-complexity) and highly divergent, and therefore sometimes tricky to discover by homology, but this model finds most examples. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	8.67533e-19
NC_018828.1|WP_003815183.1|4421806_4422679_+|RNase-adapter-RapZ	gnl|CDD|235450	PRK05416, PRK05416, RNase adapter RapZ.	1.18739e-149
NC_018828.1|WP_003815193.1|4428724_4429627_+|acetylglutamate-kinase	gnl|CDD|234869	PRK00942, PRK00942, acetylglutamate kinase; Provisional.	1.71108e-158

Protein sequences

>NC_018828.1|WP_003815191.1|4427068_4427560_+|TlpA-family-protein-disulfide-reductase
MKKIALVLIIAVAAGIGGWFMWRPAQTAPDVAFTTLEGQKITMQDLRGKVVLVKFWATSCVTCVKQMPDNIANYNQYHPQGYETIAVAMNYDPPNYVLNFAQTRKLPFPVALDTSGELAQAFGNVRLTPTAFLIDKQGQIIKRYLGEYDKAEFQATVQKALAG
>NC_018828.1|WP_003815190.1|4426328_4427072_+|BON-domain-containing-protein
MMPDAKTAARPLLLAAALSAAALTLSACAPLVIGGAAATTAVVVTDRRTSGVQLEDQNIAFKAESQIAQKLGNTARVNAMVYGGHVLLTGDAPTEEAKAQATAIAQSIENVKAVTNQLTVGPAADFSTRSNDTWLTSKVKTALINTKYVPSGTISVTTSRGVVYLMGKVTQAEGDYAANAAAGVGGVARVVKLFETISREEAIRLSGSGTKSGEGSSDGTAAQKAPIESGAAPAGSGSNGVEAIPIK
>NC_018828.1|WP_033446211.1|4425738_4426332_+|phosphoheptose-isomerase
MDMTSRMTSHFRDAMALCEQSADALAAPLAAAVDLLFAALANNGRILACGNGGSAADAQHFIAELVGRFERERLPLAGIALNTDTSIMTAVGNDYGFDEIFERQVHALGQPGDVLVAISTSGNSPNVVRAMETAREREMHVIALTGKGGGVMGELITPHDVHLCVPHDRTMRIQEVHIILLHALCDGIDALLLGDTE
>NC_018828.1|WP_015040603.1|4425196_4425730_+|YraN-family-protein
MTDTATRLAFARAAQAQRRLHRRPPASPRARPGARDGGSPTQRRGQAYESAALRWLARQGLRPLARNLRCRAGEIDLAMRDGEVLVLVEVRARAHAGYGGAAASIGASKQGRLARAAALLLPVLLRRYWPGAPPPVRFDVVAFEAGRPHWLRGAFWLAEHAPAQGRRGQDAQGWRVR
>NC_018828.1|WP_003815186.1|4424191_4425130_-|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase
MNQDVLSPAPGDAWSRVADRVAAQHWPAATLYVIATPIGNLGDLGLRAWQALVRADVIAAEDTRASRTLLDAWGVSTPLMAAHRHNEASAAQAICERLAQGQRVALVSDAGAPAVSDPGARIVRAVREAGYAVVPVPGPSAVIAALMGSGATSDENPAFAFAGFPPAKAVARQRWLRQWCALPAPVVMFESPHRLAATLADLREAGGPARLLTVARELTKRFEEIATMPLGEAADWLAADAHRGQGEFVLIVHQAPGAQDDEADPADPRTDALLDALLESLSVRDAARVAAKVTGLARDVLYARALARKEQP
>NC_018828.1|WP_003815185.1|4423622_4424195_-|methylated-DNA--[protein]-cysteine-S-methyltransferase
MNPPSEQATDILYCDTDTPLGPMRLAARGQALCGAWFVDQRDCPAAAGWTPDAAHPALRQAAAELEQWFAGRRRAFEVDMQPEGTPFQRQVWQALLELPFGATISYGELARRVGRPKAARAVAGAVGRNPISILIPCHRIIGHDTSLTGFGGGLPRKQALLAHEGHRYLSRAARARRVSTTQMELPFGAA
>NC_018828.1|WP_003815184.1|4422675_4423626_+|septal-ring-lytic-transglycosylase-RlpA-family-protein
MIRSRPLALLSTLLLALAIAGCSTPGKKRGGYYKDDGPDANPPSNLDNVPDATPRLEPLASGPNRPYVVFGKRYVPDTSERPFRQQGLASWYGKKFHGNSTSNGESYDMYAMTAAHPTMPIPSYARVTSKINGRTVIVRVNDRGPFHSDRIMDLSYVAAHKLGIIGPGSGPVTVERILPAEILAMNGGAAAPRPGPASATGPLPVAAPSAAAAVELHPATQLASNAPTPPRPATGAGSGIYLQLGAFSQPANAESLVSRINGQLDPASGIPPAVVEQANNLYRVRIGPYATREAALGAVQPVADRTGILPSLSATP
>NC_018828.1|WP_003815183.1|4421806_4422679_+|RNase-adapter-RapZ
MLRVVLITGISGSGKSVALRLLEDAGFTCIDNLPVRFLAEFIANARDDAMERVAVAIDVRSPGELAELPDVITASRAMGTSLSVIFLDANTDTLVQRYSESRRRHPLTDRLARGGKTPSLAECIALERELMAPLRDQEHVIDTSDLTPGQLRAWIRDLIQADRPPLVLTFESFAYKRGVPSDADLMFDVRCLPNPYYDRTLRPLTGRDEPVATWLGGFDIVTQMIDDIAAFIRRWLPQYTQDTRNYLTVAIGCTGGQHRSVYVVEQLARRFSDHDPLLVRHRTQLPDDPA
>NC_018828.1|WP_033446463.1|4420882_4421497_-|c-type-cytochrome
MAARVAACTACHGEQGRAGPDGYYPRLAGKPQDYLYHQLLNFRDARRQYPPMAHLLNGLPDAYLREMAAYFAGQDVPYPPPARVEASAALVERGRLLVREGDPARAIPSCASCHGASLAGVAPAIPGLLGLPRDYLVAQIGSWQNGLRRAAEPDCMAQVSLKLTPEDIGAVSAWLAGQPVGHPYTPQPAGSLTLPLECGSQAGH
>NC_018828.1|WP_003815180.1|4418580_4419507_+|HPr-kinase/phosphorylase
MLTVQELVDDNADKIPFSWIAGHDAADRAIPDDGMAAADLVGHLNLIHPSRIQVFGQEELAYYTRFDLRRRMHHMDELLIGGVPAILLADGLTPPQDLIDQCAQHQVPLLSTPVAAAQLIDLLRIYLGKKLAPTTTVHGVFLDVLGLGVLITGESGLGKSELALELISRGHGLVADDAVELSRTAPGVIEGHCPQLLQNLLEVRGLGLLDIRTIFGETSVRRKMRLKLIVHLVRATAQDKFERLPLQDITQDMLGLPIRKVMLQVAAGRNLAVLVEAAVRNTILKLRGIDTLGEFMERQAMAILQSSK
>NC_018828.1|WP_015040604.1|4427674_4428463_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MRMNFVRSALLASAFLLAGGAAQAEKLVVGATQVPHAEILEVVKPALAKEGVELDIKVFTDYVQPNLQLADKQLDANFFQHQPYLDTFNKDRKTNLVSVGLVHVEPFGGYSKKIKSLAELKDGAIIAIPNDPSNSGRALLLLQKQGLLKLKDPSNIVATPIDIAENPKKLKFRELEAAMLPRSLDDLDLALINTNYALEAGLVPTRDALFIEGADSPYANLVAARPDNKDAPAVKKLVNALHSEAVRKFIIEKYKGAVVPAF
>NC_018828.1|WP_003815193.1|4428724_4429627_+|acetylglutamate-kinase
MTDTPDPAAVLSPAVKAAVLSEALPYIRRFHGKTIVVKYGGNAMTEERLQRSFAHDVVLLKLVGLNPVVVHGGGPQIDDALRRIGKQGTFVQGMRVTDAETMEVVEWVLGGQVQQDIVMMINEVGGKAVGLTGKDGMLIQATKKLMVNKDDPSQPLDIGFVGDITRVEPAVVKALQDDQFIPVISPIGYGEDGTAYNINADVVAGKMAEVLGAEKLLMMTNTPGVLDKGGKLLRSLSAQTIDELFADGTISGGMLPKISSSLDAAKNGVNSVHIVDGRVPHCLLLEILTDQGVGTMISSH
>NC_018828.1|WP_003815194.1|4429626_4430373_+|pyrimidine-5'-nucleotidase
MQARRYLLRPAARLRRSRRIATAAPERLWLFDLDNTLHDTSHAIFPLIDRGMTEAVAETLAVDEATANRLRAEYWRRYGATVIGLVRHHGVDADAFLHRSHNFEVAPLVRAETALADKLRRLPGRKVLLTNAPLHYARAVLRHLGLLRQFDSIWAIEQMRMHGQFRPKPSDALLRYVLAREGVPAARAVLIEDTLDNLRSARRVGLRTVHVFHPGTPFARGHRQRPGYVDLRVNSVSDLLLRRRPLRG
>NC_018828.1|WP_010927138.1|4430422_4430998_+|nucleoid-occlusion-factor-SlmA
MASKPGERKTQILHTLAEMLEQPHAARITTSALAARMQVSEAALYRHFASKAQMFEGLIEFIETSIFTVVNQIAVSEPYGMGQARKTVAMLLAFAERNRGITRVLTGDALVTEDNRLQERINHINDRIEASLKQCLRVAVSDGALPADANIAAHASLLTHLVLGRWLRYAQSGWRVAPTTHLEEHLRLALG
>NC_018828.1|WP_015040605.1|4431210_4432704_+|DASS-family-sodium-coupled-anion-symporter
MTAPAAVPAPQSPPKVKIPIGLIAGIIAMVVVLLLPLPAELPPAGHRMLAILAFAVVVWITEAVSYEASAIMITTLMAFLLGTAPNVKNPDVLYGTSAAISMALTGFSNSALALVTGALFIAAAMTFTGLDKRIALVTLARVGTSTRRILLGAIAVTIVLSLVVPSATARSAAVVPIMLGVIAAFGVDKRSNIAAGIMIIVAQATSIWNVGIQTAAAQNLLTVGFMDKMLGERVAWSDWLIAGVPWSLLMSAVLIFVVLRLLPPESDAIASGKEAVEASLRELGPMTSAQKRLMLVSIMLLLFWSTEGKLHKFDTTSTTYFGLVLLMLPRFGVMTWKDVQTRIPWGTVIVFGVGISLGTALLTTQAGQWLGAQVVAHTGLDHLGPLGIFAILSAFLILIHLGFASATALTSAMLPILIAVLQTLPGDFNRLGMTMLLGFVVSYGFILPINAPQNMVALGTETFTAKQFAKVGIVLTIVGYLLMLLMSVTYWRWLGWM
>NC_018828.1|WP_015040606.1|4432714_4433770_+|Ldh-family-oxidoreductase
MKLSIAQAIAFGQRLLAAQGVPDDIARDVAEHLVESDRVGYTSHGLSILPNYRRVLAEGFVKADGRARLLNDRGAMLAFDGDNGFGQHVGKAVMQQAIERARQYGQCIVTLRRTHHLGRMGYYGEMAAEAGLILLAFTNVVNRPPTVAPYGGAQACLTTNPLCFAGPLPGGRPPFLVDMATSSIAVNKARVLAARGEPAPDGALIDAQGNPTNDPNALFADPSGALLPFGGHKGYAMGLVAELLAGVLSGGGTIQPEHPRNGVATNNMFAILLDPQVDFNADWRTQEVGAFIDYLHACPPQPGVDRVQYPGEYEAMNRARHAEAIEFEGAIWDSLAKLAQDLGAADALPRA
>NC_018828.1|WP_003815198.1|4433795_4434932_-|rod-shape-determining-protein-RodA
MKRLGLILLRVFTAFDWPLLLILILFTLLGLTVMHSAVGSTDWRFAEQSRNFLIAFAAMWAMALVPPNTLMKLALPFYVLGVILLLGVEFFGETSKGATRWLNLGVTRIQPSEMMKIAVPMMLAWYFQRHDGAVRIRDFFVAAAMLAAPFVLIVLQPDLGTALLVFGAGFFVIYFAGLSFKLLVPCLLAGIIAIGTLIYYEDQLCEPEVDWVVLHDYQKHRVCTLLNPSSDPLGKGFHTIQSMIAVGSGGLYGKGYMQGTQTHLDFIPERTTDFIFAVYAEEFGLYGGVALLVLYGLFMARGLAIASRASSQFGRLLAGAITMMMFIYVFVNVGMVTGILPVVGVPLPFMSYGGTALLTMGIACGILMSISRRRPAPA
>NC_018828.1|WP_003815201.1|4434928_4436881_-|penicillin-binding-protein-2
MFEFKKTGQQQKQRFRLRAWVGGLFALACFGVLAGRFWYLQVDRYEGFSERADRNRIAVVPIPPRRGEILDRNGEVLARNYRTYTLEVVPAQAGNLDQLFDRLARVVYISPSDQRRFKRRVGESSRYASLQLRNNLNDTEAAWFSAHSFEFPGVELRARWVREYPQGEAAAHVVGFIGRIAENDIEELDKAGQLGNYRGTDVIGKKGIEKTWEAALHGRTGLEEVEVTAGGRPMRTLRRIDPVPGSDIMLSIDLELQKLAEQAFEGRRGALVALDPDTGEVLAFVSQPSFDPNLFVDGIDVENWRRLNESPDHPLINRPLYGTYPIGSTYKPFVALAALELGKRRATDRMPDPGYFEFGGQKFRNAGGAAYGMTDMHRAIVVSSDTYFYSLGPEIGVNALHDFSKQFGFGQITGIDLEGEKAGVLPSTEWKRKAYKDRDRQRWYAGETISVAVGQGYNSFTLLQLAQATSTLANSGLYRRPHLVHAIRDSRSGSVNPTEIAPDYRIPLKQENVDVIKRAMADVVRAGTARRAFAGAPYQAAGKTGTAQVFSLRGGQYRASAIDERLRDHALFMGFAPVEQPRIAVALIVENAGWGASAAAPIARTLFDNWLGRADAPSVVRAGAKPVAAEPEAAALELGATDGPMQERRQ
>NC_018828.1|WP_015040607.1|4436894_4437458_-|rod-shape-determining-protein-MreD
MERTKVSVPARRKLGTPSNVEPERLARPAHGVFVWGTVLLVWLLSLLPWRQWPGSPDVLVLVIAFWCVHEPRRVGLLTAFVFGLLLDVHDAGLLGGHALSYTLTAYGAIALHRRLQRFDLWSQAMHMLPVFFLAQLVTQIILAWLAGKWPGWQWAVSVGLTVAIWPLAGWVLHMPQRRYNDVESSAV
>NC_018828.1|WP_003815203.1|4437444_4438329_-|rod-shape-determining-protein-MreC
MQRQATPPLFRRGPPAEVRLAVLVILALALLIVDSQLRVLEPVRRAVSVALYPFQRAVMAPRDLVQQVDEWINAASLIRSENEALQRQRIELAQVATHAAQLAAENAQLRRLLGVTDTVAQSAVVVEVLYEPPNAFHQRLVFNKGAKSGLAPGMPVIDEGGVVGQIVRVTPMTAEAALVTDERVSIPVQVLRNGLRLIAFGANTPGVIEVRYLAANADIKVGDTIVTSGVGGLFPAGLPVAKVASVERDTASGFARALGEPLAHPERYRHFLVLQVDVDQAESNRQEADVDGAD

Crispr_ID: NC_018828_9

• CRISPR_ID: NC_018828_9
• CRISPR_location: 4510102-4510182
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_018828_9

Consensus_repeat	Method
GTGCCTGTCCCCGCGGGGACAGGCACCT	CRISPRCasFinder

spacers of NC_018828_9

>9.1|4510130|25|NC_018828|CRISPRCasFinder
TGTGCCGGCCCTCCGCAACGCTCGG

CRISPR arrays and Neighbor proteins around NC_018828_9

CRISPR arrays

The CRISPR arrays of NC_018828_9

>merge|NC_018828|9|4510102-4510182|CRISPRCasFinder
GTGCCTGTCCCCGCGGGGACAGGCACCTTGTGCCGGCCCTCCGCAACGCTCGGGTGCCTGTCCCCACGGGGACAGGCACCT

>NC_018828|9|8|4510102-4510182|CRISPRCasFinder
GTGCCTGTCCCCGCGGGGACAGGCACCT	TGTGCCGGCCCTCCGCAACGCTCGG
GTGCCTGTCCCCACGGGGACAGGCACCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018828.1|WP_015040647.1|4519817_4521359_-|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl|CDD|236448
NC_018828.1|WP_003815329.1|4507986_4508892_+|hydrolase	unknown	unknown	gnl|CDD|226040
NC_018828.1|WP_015040646.1|4515874_4516756_-|hypothetical-protein	unknown	unknown	gnl|CDD|225114
NC_018828.1|WP_015040640.1|4499789_4500650_+|NAD(P)H-hydrate-dehydratase	unknown	unknown	gnl|CDD|238576
NC_018828.1|WP_003815341.1|4516938_4517361_-|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl|CDD|234796
NC_018828.1|WP_003815321.1|4504089_4505067_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NC_018828.1|WP_003815337.1|4514722_4515799_-|uroporphyrinogen-decarboxylase	unknown	unknown	gnl|CDD|234644
NC_018828.1|WP_015040641.1|4500777_4501014_+|hypothetical-protein	unknown	unknown	unknown
NC_018828.1|WP_015040644.1|4505074_4505995_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NC_018828.1|WP_165446319.1|4503062_4504031_+|succinylglutamate-desuccinylase	unknown	unknown	gnl|CDD|349481
NC_018828.1|WP_015040638.1|4498062_4498800_+|enoyl-CoA-hydratase	unknown	unknown	gnl|CDD|235852
NC_018828.1|WP_003815350.1|4521945_4522416_-|F0F1-ATP-synthase-subunit-B	unknown	unknown	gnl|CDD|180240
NC_018828.1|WP_003815344.1|4518813_4519719_-|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl|CDD|235535
NC_018828.1|WP_003815348.1|4521393_4521933_-|F0F1-ATP-synthase-subunit-delta	unknown	unknown	gnl|CDD|235593
NC_018828.1|WP_015040645.1|4506973_4507984_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|226967
NC_018828.1|WP_003815333.1|4510201_4512271_-|UvrD-helicase-domain-containing-protein	unknown	unknown	gnl|CDD|130146
NC_018828.1|WP_003815343.1|4517370_4518771_-|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl|CDD|236447
NC_018828.1|WP_015040639.1|4498879_4499701_-|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|235991
NC_018828.1|WP_003815335.1|4512313_4514416_-|primosomal-protein-N'	unknown	unknown	gnl|CDD|235514
NC_018828.1|WP_015040642.1|4501310_4502939_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173863

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018828.1|WP_015040647.1|4519817_4521359_-|F0F1-ATP-synthase-subunit-alpha	gnl|CDD|236448	PRK09281, PRK09281, F0F1 ATP synthase subunit alpha; Validated.	0
NC_018828.1|WP_003815329.1|4507986_4508892_+|hydrolase	gnl|CDD|226040	COG3509, LpqC, Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport, and catabolism].	9.10797e-08
NC_018828.1|WP_015040646.1|4515874_4516756_-|hypothetical-protein	gnl|CDD|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	2.50234e-05
NC_018828.1|WP_015040640.1|4499789_4500650_+|NAD(P)H-hydrate-dehydratase	gnl|CDD|238576	cd01171, YXKO-related, B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily.	1.1734e-73
NC_018828.1|WP_003815341.1|4516938_4517361_-|F0F1-ATP-synthase-subunit-epsilon	gnl|CDD|234796	PRK00571, atpC, F0F1 ATP synthase subunit epsilon; Validated.	1.40936e-54
NC_018828.1|WP_003815321.1|4504089_4505067_+|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	7.49002e-115
NC_018828.1|WP_003815337.1|4514722_4515799_-|uroporphyrinogen-decarboxylase	gnl|CDD|234644	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated.	0
NC_018828.1|WP_015040644.1|4505074_4505995_+|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	8.01135e-95
NC_018828.1|WP_165446319.1|4503062_4504031_+|succinylglutamate-desuccinylase	gnl|CDD|349481	cd06910, M14_ASTE_ASPA-like, Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like; uncharacterized subgroup. A functionally uncharacterized subgroup of the Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA) subfamily which is part of the M14 family of metallocarboxypeptidases. ASTE catalyzes the fifth and last step in arginine catabolism by the arginine succinyltransferase pathway, and aspartoacylase (ASPA, also known as aminoacylase 2, and ACY-2; EC:3.5.1.15) cleaves N-acetyl L-aspartic acid (NAA) into aspartate and acetate. NAA is abundant in the brain, and hydrolysis of NAA by ASPA may help maintain white matter. ASPA is an NAA scavenger in other tissues. Mutations in the gene encoding ASPA cause Canavan disease (CD), a fatal progressive neurodegenerative disorder involving dysmyelination and spongiform degeneration of white matter in children. This enzyme binds zinc which is necessary for activity. Measurement of elevated NAA levels in urine is used in the diagnosis of CD.	1.0474e-79
NC_018828.1|WP_015040638.1|4498062_4498800_+|enoyl-CoA-hydratase	gnl|CDD|235852	PRK06688, PRK06688, enoyl-CoA hydratase; Provisional.	8.53989e-73
NC_018828.1|WP_003815350.1|4521945_4522416_-|F0F1-ATP-synthase-subunit-B	gnl|CDD|180240	PRK05759, PRK05759, F0F1 ATP synthase subunit B; Validated.	2.79837e-52
NC_018828.1|WP_003815344.1|4518813_4519719_-|F0F1-ATP-synthase-subunit-gamma	gnl|CDD|235535	PRK05621, PRK05621, F0F1 ATP synthase subunit gamma; Validated.	1.30561e-149
NC_018828.1|WP_003815348.1|4521393_4521933_-|F0F1-ATP-synthase-subunit-delta	gnl|CDD|235593	PRK05758, PRK05758, F0F1 ATP synthase subunit delta; Validated.	1.16567e-65
NC_018828.1|WP_015040645.1|4506973_4507984_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|226967	COG4608, AppF, ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism].	1.70141e-128
NC_018828.1|WP_003815333.1|4510201_4512271_-|UvrD-helicase-domain-containing-protein	gnl|CDD|130146	TIGR01074, ATP-dependent_DNA_helicase_Rep, ATP-dependent DNA helicase Rep. Designed to identify rep members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_018828.1|WP_003815343.1|4517370_4518771_-|F0F1-ATP-synthase-subunit-beta	gnl|CDD|236447	PRK09280, PRK09280, F0F1 ATP synthase subunit beta; Validated.	0
NC_018828.1|WP_015040639.1|4498879_4499701_-|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|235991	PRK07327, PRK07327, enoyl-CoA hydratase/isomerase family protein.	0
NC_018828.1|WP_003815335.1|4512313_4514416_-|primosomal-protein-N'	gnl|CDD|235514	PRK05580, PRK05580, primosome assembly protein PriA; Validated.	0
NC_018828.1|WP_015040642.1|4501310_4502939_+|ABC-transporter-substrate-binding-protein	gnl|CDD|173863	cd08498, PBP2_NikA_DppA_OppA_like_2, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0

Protein sequences

>NC_018828.1|WP_003815329.1|4507986_4508892_+|hydrolase
MKPADLTNADRIALELGHAGRNAIPYLDDDRNADRPFTLNTYRPYGYTPDRPVVVVQHGVLRNGADYRDFWIPAADRHKLLIVAPTFSDEIWPGVESYNNGRAFTAAGNPRHVDGWTYALVARVLANIRAAEIADCEQVYLFGHSAGGQFVHRLMSSQPHAPFHAVTAANPGWYTLPTFEHRFPEGLDGVGLTEDHLARLLAYPMTILAGDQDIATDDPNLPSEPAALRQGPHRYARARHYYEAGQRAAAQRGLPFGWQLQVVPGIGHDGQAMSQVCASLWFDGRMPDAAELARLAGSQSA
>NC_018828.1|WP_015040645.1|4506973_4507984_+|ATP-binding-cassette-domain-containing-protein
MTTSDLPVIELRDVHKRFEHRPDMAQRLLALTGKPLDRRTVHAVNGVSLSVRRGEVLGLVGESGCGKSTLGRVVAGLHRESAGELLYQGRPAAQLRGADRLAYVLGVQMIFQDPQASLNPRQRLRQILAEALKVHKLAPPAEIPARVDRALAEVGLDREYRERYSHQISGGQRQRIGIARALMVEPRFLVCDEPVAALDVSIQAQVINLFMDLREQRGLTYLFISHDLGVVRHISDRVAIMYLGKIVEQASSAEIFAHPNHPYTQALMAEVPDVGRRGRVFTPIRGEIPSPLDPPPGCTFHPRCPHAMPRCRERAPVLREIAPGHVSACHLNDTAS
>NC_018828.1|WP_015040644.1|4505074_4505995_+|ABC-transporter-permease
MANPPSNGRTRTVHPLSETPRRAQILKQLHSRPTVRGSVIALLALVALILLAPYFAPQNPYDLASLNLLDGRLPPRSPTMDGGFYWLGTDDQGRDMFSAILYGLRISLLVGLTAVVLATAIGSLVGLLAAYAGGVIDAVLMRIVDFILGFPTILVALVLLAMMGRGVDKVILALVVVQWAHYARIMRGRALQERRKEYVEAAANLGFPAWRIMLFHLLPNCMAPVMVFATVQIANAIVLEATLSFLGVGVPVTEPSLGLLIANGFQYLLSGDYWISLFPGLALLLLILSINIVGDRLRESLDPRRA
>NC_018828.1|WP_003815321.1|4504089_4505067_+|ABC-transporter-permease
MALFILRRLIQSLFVLLAVSVVVFFAVYAVGDPIELLVSPEASADARQAMIARLGLDLPVWQQYGNFLWRALHGDLGNSFVHGIPAISLILQRIPATFELVLVAIVLTCTIGIPLGLVAGLHRDRPLGRGIMATSVLGFSLPNFWQGMMLILLFSVWLGWLPASGRGDTANLFGVPLSILTLDGWSHVIMPAINLAVANVALVLRLTASGVVEAQSQEYVKFARAKGIKPGRIVRRHILRNILIPVVTVIGMEFGHLIAYSTITETVFAWPGMGKLLIDSVYQLDRPVVVAYVMLVTLIFVVINLVVDILYAALDPRVQLVAPAQ
>NC_018828.1|WP_165446319.1|4503062_4504031_+|succinylglutamate-desuccinylase
MSPPPAVAAIRPFELACPRLDAERVGNGATPGVWHFDAGLPGRHVLLTALIHGNELCGAWALKDALAAGLRPRRGKLTLAFCNLAAFDRFDPLNYAPARFVDEDMNRVWSADKLAAPDTQERRRARALLPWVEQADWLLDFHSMSNADEPLQLTGTQPRNIELALKLGNPAHLVADAGHAAGVRLRDYGRFGAEGENGTRSLLIECGFHGAPASRTVARDILARFLLEAGTLAADDIPPGWLADAAPRQRALRVTHAVAARSADFRFAQPWQGLERIARAGTVIGWSDGEPVATPYDDCVLIMPSLANLRPGVTVVRLAQPI
>NC_018828.1|WP_015040642.1|4501310_4502939_+|ABC-transporter-substrate-binding-protein
MKLRTTLALLATSAGLAAAPGSASAQSLKIALSSEPTSADPHYHKQTQNDAFSAHVYSSLIGRDADMKLVPALATSWKNLDDLTWEFKLRDDAKFSNGKPFTSEDVLFTICRTLNNETNVSQSYMDTTKRIADVQTPDAHTVIIKTAAPLPLLPAELARSLPIVWNGIVEHGKLTFNPKEGCGVTGPWPTVADFNNGKDAIGTGPYKLKSYVKGTGIELERNDNYWGPKPYWKDVKMVPVPNAGPRLTGLLSGDFDVIENPAARDLPRIKSNPQFGFVATPSTRLIFFQPDVGRNPSPLVKSADGKNPLQDLRVRQAISMAIDRKTIVTRLMDGIATPAYQYMPDGMFGGVPNAPEIKYDPEGAKKLLAEAGYANGFELTISTPNDRYVNDGQIAQAVAQYLSRVSIKANVDAMTASLYFPKRAKREFSFSMGGWPAEVGEASALFQLWVASLDSPRSLGTSNYGGFSNAEFDKVFTEALVTVDVAKREKLLQQSTQIALDNVPLIPLHFESSIWAFRKGLTYEGRRDQFTLAMSVQPADQK
>NC_018828.1|WP_015040641.1|4500777_4501014_+|hypothetical-protein
MSDLTLSHNARLTDSLERELLRGAMEDQSNTIRPLAAVKAAAVGVGCGVRAVFAFIDEVNESMNRARAQSAHYTGSQW
>NC_018828.1|WP_015040640.1|4499789_4500650_+|NAD(P)H-hydrate-dehydratase
MDTSSSSLPAIERQHLPALFAARPTDAHKGSCGTLGVIGGGPGMVGAALLAARAGLKVGAGKVLVGLVAETPPLPCDPMQPELMLRDFRGLLEAGLGIDAWTAGCGCGMDALAANALSELFQLRGDAALVLDADGLNLLAAGAVQPRWGDAPVVLTPHPVEAGRLLGLSTEAVQADRPAAARTLAARYGAWVVLKGAGSIVCDPAGACRINRTGNPGLATAGTGDVLAGILGALLAQRIAPEQAVPGAVWLHGAAADALVTHGIGPMGLTAGELADSARRLRNSRA
>NC_018828.1|WP_015040639.1|4498879_4499701_-|enoyl-CoA-hydratase/isomerase-family-protein
MSETDTNPEHYARYRALRIRRHPEGILELVMGAKDASGKLSTADERLHRELADVWRDVDTDDQTRVVVIRGEGNGFSGGGDLGLVQQMAEDFEVRTRVWREARDLVYNIINCNKPIVSAMHGAAVGAGLVAGLLADISIAARDARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYLLLCDAVSGEEAERIGLVSLCVDRAELLSKAFEVAGRLAAGSQTAIRWTKYALNNWLRMAGPSFDTSLALEFMGFAGPDVHEGIKSLREKRAPDFR
>NC_018828.1|WP_015040638.1|4498062_4498800_+|enoyl-CoA-hydratase
MNSLLTERDAAVLTLTINRPERRNALDTATYDALAAQLRAADADTGLAAVILTGAGDHFAAGNDLRDFQAERAAGDSPALRFLRALVDTDVPVLAAVEGHAVGVGVTLLQHCDFAFAAGTARLRMPFVALGLCPEGASSLLLPRLAGMRKAAEWLLQGRAFDAAEAHAAGLLTGVTEPGQALAAARAVAADLAAQPRQALRVSKRMLRQADRAAIHATLDHEAEQFRERLRSPEAQQAFARFFNK
>NC_018828.1|WP_003815333.1|4510201_4512271_-|UvrD-helicase-domain-containing-protein
MSASDTSIGSGLNPSQKEAVLYLDGPCLVLAGAGSGKTRVITQKMAYLLRECGYMGRNIVALTFTNKAAREMAERVKTLVDPKLAKGLTISTFHALGVRLLREEAAHAGLKPQFSILDADDAMSIIQELLATTDRGRLREVQSIISLWKNALLTPDQAAAAAITPTEVEAVTVYRGYAATLAAYQAVDFDDLIRIPAELLERNEEVRTRWQNRVRYLLVDEYQDTNVCQYRLVQLLTGVRAMFTAVGDDDQAIYAWRGATIENLAKLTTDYPNLKLIKLEQNYRSVQRILAAANNVIERNPKLFEKKLWSDLGHGEPIIVSPMNGDEHEAESIAMKVSAARFERQAQWKDFAILYRSNHQSRVLEQALRNLKIPYTISGGQSFFDKAEVRDILAYLRLVANDEDDPAFIRAATTPKRGIGQGTLQTLGQYAAQRQCSLLAAVDEAGLESLLAPRQLEPLRTFAEFVRRIQWRAGRGVEGQPARAPEPAGQILDDLLSAIQYERYLYDMLEERPAQTRWQNVLELTGWLKRKAEEDGMTLFDLVQHVALVTMLERGEEEEPDAVKLSTLHASKGLEYPHVYLAGVEEGLLPHLGKDDEDSGDPARAAETLATRIQEERRLMYVGITRAQRSLNLSWCKKRRRAREDVVREPSRFIEEMGLGDAKVQEDEATRAMSPKERLGMLKALLKKD
>NC_018828.1|WP_003815335.1|4512313_4514416_-|primosomal-protein-N'
MSDASSADPALPAADAAGVWVRVALDVPLPGPFDYRSAAPLPLGARVIVPFGRRKLVGVVVEHPAQPSIDPAQVREVEQPLEDLPPMPADWMRLARFAADYYQRPLGEVMLPVLPPPLRKPSAYQGKRSGLGPVARLDARKPRAEAAVAAEPDQAPELNEAQREAVDTIGALSAFQPVLLHGVTGSGKTEVYLHAAARVLQAGRQVLLMVPEINLTPQLEGALRARLEALVGPQGVAILHSGLADGERVQAWARAQRGQARLLLGTRMSIFAPLPELGLIVVDEEHDPSYKQQEGLRYSARDLAIWRARDLDIPVVLGSATPSLESWQHAERGRYLRLTLPGRARASSLPEIRLIDTRRLQLKQGLAPQFIEAIGQRLERGEQSLVFLNRRGYAPVLHCASCAWVSHCPRCSTFTVLHRGPGAGGYRLQCHHCGYQAPVPRACPECGDQDLEPMGRGTQRIEEQLAEWFPQARIARIDADSTRRKGSAQALFAAVHAGEVDIMVGTQMVAKGHDFARLGLVGVLNADSMLFAHDFRAPERLFAQLMQVAGRAGRHAAGAQVLIQTGYPEQPVYQALLRHDYAGFARHALQEREDTGLPPFAYQALLTAEARELTVAQGFLQRARDLATGEPWPGVDAITLYDPVPLRVVRVAHVERAQLLIESTSRPALQGFLTAWAACLPQLAAEARVRWQLEVDPLEI
>NC_018828.1|WP_003815337.1|4514722_4515799_-|uroporphyrinogen-decarboxylase
MSVAPLKNDVFLRALLREPVPYTPIWLMRQAGRYLPEYNATRARAGSFMGLAQNPDYACEVTLQPLARYPLDAAILFSDILTVPHAMGLGLDFAPGEGPRFAHPVRDESDVAKLAVPDMDSLRYVFDAVRTIRRELDGRVPLIGFAGSPWTIACYMVEGRGSDDYRLIKSMLYGRPDLLHRILEINAEATRHYLNAQIDAGAQAVMLFDSWGGVLADGLFQQFSLAYTRRVVEGLTREREGRRVPVIVFTKGGGQWLEEIAACGCDAVGLDWTVNLGTARRRVADAVALQGNLDPMTLFGGAQAVRAEARRTLDAFGPVGKGGHVFNLGHGISQYSPPEVVSELVDEVHTYSRALHAG
>NC_018828.1|WP_015040646.1|4515874_4516756_-|hypothetical-protein
MRALLECAVLVMPDQPSWVGTWLAAVRGPDARLADRLRLHEYPLSGGRDGLALGQAAMSLRRFDALLLPVQASTLGWARLVLAQASPALSTPVLVLVRDLTAPAIADLLRLGARDFLRVPACLDELRVRASRAWRAIPPPTAGARAAVPVPGAEPGGGPGPGAPTDPGEGGGYRLPGMPETADAPAAAPCMLAQACAPYAATLGDARMAVQRELPFRQAKAQVVGRFERAYLRGALARHGGNVAQAARAACKHRRAFWALMRKHGIDARPYREGMAGAWPYETAPPRDPADEA
>NC_018828.1|WP_003815341.1|4516938_4517361_-|F0F1-ATP-synthase-subunit-epsilon
MATLHVDVVSAEEAIFTGEAKFVVLPGEAGELGILPGHTPLISRIRPGTVKIVRADEGEENIFVAGGILEVQPGSVTVLADTAIRAADLDEARAVAAREKAEEALRNAKDKADIAVVEAELAMLAAQAVAARKLRQGRTH
>NC_018828.1|WP_003815343.1|4517370_4518771_-|F0F1-ATP-synthase-subunit-beta
MSNGTIVQCIGAVVDIQFPRDNMPKIYEALTLVDEGSSFAEKGLTLEVQQQLGDGVVRTIALGSSDGLRRGMQVAGTGAPISVPVGHGTLGRIMDVLGRPIDEAGPIASDEKRAIHQPAPRFDELSPSVELLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKQHSGLSVFAGVGERTREGNDFYHEMEESNVLDKVAMVFGQMNEPPGNRLRVALTGLTMAEKFRDEGRDILFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSIQAVYVPADDLTDPSPATTFQHLDSTVVLSRDIAALGIYPAVDPLDSSSRQLDPQVVGEEHYQVARGVQQTLQRYKELRDIIAILGMDELSPEDKQAVARARKIQRFLSQPFHVAEVFTGSPGKYVSLAETIRGFKMIVDGECDALPEQAFYMVGTIDEAFEKAKKLQ
>NC_018828.1|WP_003815344.1|4518813_4519719_-|F0F1-ATP-synthase-subunit-gamma
MPGIKEIRTKIKSVQNTRKITKAMEMVAASKMRKAQERMRAGRPYATKVREIAAHLMQANPEYSHPYLVEREVKAVGVVLVTTDKGLCGGLNTNISRVTLSKLKEFEQRSIKVQATAFGNKGLGLLTRIGAKLVSQEVQLGDKPDLDRLLGAIKVQLDDYLEGRIDALYVATTRFVNTMRQEPVFLRLLPLSNGLDDPFQSGVETLAKTAEIKSDYSWDYIYEPDAKSVIDDLLQRYVEGLLYQAVAENMASEQSARMVAMKSASDNAKKVIGDLQLVYNKTRQAAITKEISEIVGGAAAV
>NC_018828.1|WP_015040647.1|4519817_4521359_-|F0F1-ATP-synthase-subunit-alpha
MQLNPSEISELLKSRIEGLGASTDVRTQGTVVSVTDGITRIHGLSDVMQGEMLEFPNNVFGVALNLERDSVGAVVLGDYTGVSEGDQVKTTGRILEVPVGPELKGRVVNTLGDAIDGKGPINTTQTDIIEKVAPGVIARRSVSQPLQTGIKAIDSMVPIGRGQRELIIGDRQTGKTAVAVDTIISQKGKGVTCVYVAIGQKASTINNVVRKLEEHGAMEYTIVVAAAASDSAAMQYLAAYAGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNEEYVEKFTNGAVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGVRPAINAGISVSRVGGAAQTKVIKKLSGGIRTDLAQYRELAAFAQFASDLDDATRRQLERGKRVVELLKQPQYQPLQVWELAVSLYAVNNGYLDDVDVAQILAFEKSLKDHLKAKHAALIQRIEDTKELSKDDEAELAAAIQDFKKHGAF
>NC_018828.1|WP_003815348.1|4521393_4521933_-|F0F1-ATP-synthase-subunit-delta
MAELSTVARPYAEALFGAARDDKAGLAVWADLVSEMAQVAANPDVREAMADPRLDDKQRSEVFTGLIKSQLPQAARNFIELLVKNDRLLLLPVIATQFVALKNRHEGTAQAEITSAFELSDAQVKELIAALELKFGLKLKPHVSVDQELIGGVRVAVGDQVLDTSVKAQLARLRDTLAA
>NC_018828.1|WP_003815350.1|4521945_4522416_-|F0F1-ATP-synthase-subunit-B
MNLNATIFFQMLVFFVLGWFTMKFVWPPLTKAIDERRQKIADGLAAAEKGKADLAQAQARVSLIEASAKSETHARIIEAEKQAASVIEQARREAEAERARIVAQAAQDAAQEVQRAREALRDDVAALAVKGAEQILKREVDARAHAELLNQLKAQL

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	NC_018828.1	1751160-1751189	0	1.0
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	NC_018828.1	1751388-1751417	0	1.0
NC_018828_4	4.2|2259121|54|NC_018828|CRT	2259121-2259174	54	NC_018828.1	1751220-1751273	0	1.0
NC_018828_4	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	NC_018828.1	1751256-1751297	0	1.0
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	NC_018828.1	1751172-1751201	0	1.0
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	NC_018828.1	1751316-1751345	0	1.0
NC_018828_4	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	NC_018828.1	1751364-1751381	0	1.0
NC_018828_4	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	NC_018828.1	1751412-1751429	0	1.0
NC_018828_4	4.7|2259421|42|NC_018828|CRT	2259421-2259462	42	NC_018828.1	1751400-1751441	0	1.0
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	NC_018828.1	1751172-1751201	1	0.967
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	NC_018828.1	1751304-1751333	1	0.967
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	NC_018828.1	1751316-1751345	1	0.967
NC_018828_4	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	NC_018828.1	1751076-1751117	1	0.976
NC_018828_4	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	NC_018828.1	1751112-1751153	1	0.976
NC_018828_4	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	NC_018828.1	1751208-1751249	1	0.976
NC_018828_4	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	NC_018828.1	1751232-1751273	1	0.976
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	NC_018828.1	1751160-1751189	1	0.967
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	NC_018828.1	1751328-1751357	1	0.967
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	NC_018828.1	1751340-1751369	1	0.967
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	NC_018828.1	1751388-1751417	1	0.967
NC_018828_4	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	NC_018828.1	1751064-1751081	1	0.944
NC_018828_4	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	NC_018828.1	1751076-1751093	1	0.944
NC_018828_4	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	NC_018828.1	1751112-1751129	1	0.944
NC_018828_4	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	NC_018828.1	1751196-1751213	1	0.944
NC_018828_4	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	NC_018828.1	1751208-1751225	1	0.944
NC_018828_4	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	NC_018828.1	1751256-1751273	1	0.944
NC_018828_4	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	NC_018828.1	1751280-1751297	1	0.944
NC_018828_4	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	NC_018828.1	1751448-1751465	1	0.944
NC_018828_4	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	NC_018828.1	2259469-2259486	1	0.944
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	NC_018828.1	1751040-1751069	2	0.933
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	NC_018828.1	1751052-1751081	2	0.933
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	NC_018828.1	1751328-1751357	2	0.933
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	NC_018828.1	1751340-1751369	2	0.933
NC_018828_4	4.2|2259121|54|NC_018828|CRT	2259121-2259174	54	NC_018828.1	1751088-1751141	2	0.963
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	NC_018828.1	1751184-1751213	2	0.933
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	NC_018828.1	1751304-1751333	2	0.933
NC_018828_4	4.7|2259421|42|NC_018828|CRT	2259421-2259462	42	NC_018828.1	1751184-1751225	2	0.952
NC_018828_4	4.7|2259421|42|NC_018828|CRT	2259421-2259462	42	NC_018828.1	1751352-1751393	2	0.952
NC_018828_4	4.3|2259193|66|NC_018828|CRT	2259193-2259258	66	NC_018828.1	1751376-1751441	8	0.879

1. spacer 4.1|2259073|30|NC_018828|CRT matches to position: 1751160-1751189, mismatch: 0, identity: 1.0

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

2. spacer 4.1|2259073|30|NC_018828|CRT matches to position: 1751388-1751417, mismatch: 0, identity: 1.0

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

3. spacer 4.2|2259121|54|NC_018828|CRT matches to position: 1751220-1751273, mismatch: 0, identity: 1.0

actggcagcggccctggcagcggccctggcagcggccctggcagcggcactggc	CRISPR spacer
actggcagcggccctggcagcggccctggcagcggccctggcagcggcactggc	Protospacer
******************************************************

4. spacer 4.4|2259277|42|NC_018828|CRT matches to position: 1751256-1751297, mismatch: 0, identity: 1.0

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggcactggcagcggccctggcagcggcactggc	Protospacer
******************************************

5. spacer 4.5|2259337|30|NC_018828|CRT matches to position: 1751172-1751201, mismatch: 0, identity: 1.0

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

6. spacer 4.5|2259337|30|NC_018828|CRT matches to position: 1751316-1751345, mismatch: 0, identity: 1.0

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

7. spacer 4.6|2259385|18|NC_018828|CRT matches to position: 1751364-1751381, mismatch: 0, identity: 1.0

ccaggcagcggcactggc	CRISPR spacer
ccaggcagcggcactggc	Protospacer
******************

8. spacer 4.6|2259385|18|NC_018828|CRT matches to position: 1751412-1751429, mismatch: 0, identity: 1.0

ccaggcagcggcactggc	CRISPR spacer
ccaggcagcggcactggc	Protospacer
******************

9. spacer 4.7|2259421|42|NC_018828|CRT matches to position: 1751400-1751441, mismatch: 0, identity: 1.0

ccaggcagcgtcccaggcagcggcactggcatcggcactggc	CRISPR spacer
ccaggcagcgtcccaggcagcggcactggcatcggcactggc	Protospacer
******************************************

10. spacer 4.1|2259073|30|NC_018828|CRT matches to position: 1751172-1751201, mismatch: 1, identity: 0.967

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

11. spacer 4.1|2259073|30|NC_018828|CRT matches to position: 1751304-1751333, mismatch: 1, identity: 0.967

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtaccaggcagcgtcccaggc	Protospacer
*********** ******************

12. spacer 4.1|2259073|30|NC_018828|CRT matches to position: 1751316-1751345, mismatch: 1, identity: 0.967

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

13. spacer 4.4|2259277|42|NC_018828|CRT matches to position: 1751076-1751117, mismatch: 1, identity: 0.976

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggcactggcagcggccctggcagcggccctggc	Protospacer
************************************ *****

14. spacer 4.4|2259277|42|NC_018828|CRT matches to position: 1751112-1751153, mismatch: 1, identity: 0.976

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggcactggcagcggccctggcatcggcactggc	Protospacer
******************************* **********

15. spacer 4.4|2259277|42|NC_018828|CRT matches to position: 1751208-1751249, mismatch: 1, identity: 0.976

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggcactggcagcggccctggcagcggccctggc	Protospacer
************************************ *****

16. spacer 4.4|2259277|42|NC_018828|CRT matches to position: 1751232-1751273, mismatch: 1, identity: 0.976

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggccctggcagcggccctggcagcggcactggc	Protospacer
************ *****************************

17. spacer 4.5|2259337|30|NC_018828|CRT matches to position: 1751160-1751189, mismatch: 1, identity: 0.967

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

18. spacer 4.5|2259337|30|NC_018828|CRT matches to position: 1751328-1751357, mismatch: 1, identity: 0.967

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcggcccaggc	Protospacer
********************** *******

19. spacer 4.5|2259337|30|NC_018828|CRT matches to position: 1751340-1751369, mismatch: 1, identity: 0.967

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcggcccaggcagcgtcccaggc	Protospacer
********** *******************

20. spacer 4.5|2259337|30|NC_018828|CRT matches to position: 1751388-1751417, mismatch: 1, identity: 0.967

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

21. spacer 4.6|2259385|18|NC_018828|CRT matches to position: 1751064-1751081, mismatch: 1, identity: 0.944

ccaggcagcggcactggc	CRISPR spacer
ccaggcagcggccctggc	Protospacer
************ *****

22. spacer 4.6|2259385|18|NC_018828|CRT matches to position: 1751076-1751093, mismatch: 1, identity: 0.944

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

23. spacer 4.6|2259385|18|NC_018828|CRT matches to position: 1751112-1751129, mismatch: 1, identity: 0.944

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

24. spacer 4.6|2259385|18|NC_018828|CRT matches to position: 1751196-1751213, mismatch: 1, identity: 0.944

ccaggcagcggcactggc	CRISPR spacer
ccaggcagcggccctggc	Protospacer
************ *****

25. spacer 4.6|2259385|18|NC_018828|CRT matches to position: 1751208-1751225, mismatch: 1, identity: 0.944

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

26. spacer 4.6|2259385|18|NC_018828|CRT matches to position: 1751256-1751273, mismatch: 1, identity: 0.944

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

27. spacer 4.6|2259385|18|NC_018828|CRT matches to position: 1751280-1751297, mismatch: 1, identity: 0.944

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

28. spacer 4.6|2259385|18|NC_018828|CRT matches to position: 1751448-1751465, mismatch: 1, identity: 0.944

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

29. spacer 4.6|2259385|18|NC_018828|CRT matches to position: 2259469-2259486, mismatch: 1, identity: 0.944

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

30. spacer 4.1|2259073|30|NC_018828|CRT matches to position: 1751040-1751069, mismatch: 2, identity: 0.933

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcggccctggcagcgtcccaggc	Protospacer
********** *** ***************

31. spacer 4.1|2259073|30|NC_018828|CRT matches to position: 1751052-1751081, mismatch: 2, identity: 0.933

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcggccctggc	Protospacer
********************** *** ***

32. spacer 4.1|2259073|30|NC_018828|CRT matches to position: 1751328-1751357, mismatch: 2, identity: 0.933

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcggcccaggc	Protospacer
** ******************* *******

33. spacer 4.1|2259073|30|NC_018828|CRT matches to position: 1751340-1751369, mismatch: 2, identity: 0.933

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcggcccaggcagcgtcccaggc	Protospacer
** ******* *******************

34. spacer 4.2|2259121|54|NC_018828|CRT matches to position: 1751088-1751141, mismatch: 2, identity: 0.963

actggcagcggccctggcagcggccctggcagcggccctggcagcggcactggc	CRISPR spacer
actggcagcggccctggcagcggccctggcagcggcactggcagcggccctggc	Protospacer
************************************ *********** *****

35. spacer 4.5|2259337|30|NC_018828|CRT matches to position: 1751184-1751213, mismatch: 2, identity: 0.933

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcggccctggc	Protospacer
********************** *** ***

36. spacer 4.5|2259337|30|NC_018828|CRT matches to position: 1751304-1751333, mismatch: 2, identity: 0.933

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtaccaggcagcgtcccaggc	Protospacer
** ******** ******************

37. spacer 4.7|2259421|42|NC_018828|CRT matches to position: 1751184-1751225, mismatch: 2, identity: 0.952

ccaggcagcgtcccaggcagcggcactggcatcggcactggc	CRISPR spacer
ccaggcagcgtcccaggcagcggccctggcagcggcactggc	Protospacer
************************ ****** **********

38. spacer 4.7|2259421|42|NC_018828|CRT matches to position: 1751352-1751393, mismatch: 2, identity: 0.952

ccaggcagcgtcccaggcagcggcactggcatcggcactggc	CRISPR spacer
ccaggcagcgtcccaggcagcggcactggcagcggccctggc	Protospacer
******************************* **** *****

39. spacer 4.3|2259193|66|NC_018828|CRT matches to position: 1751376-1751441, mismatch: 8, identity: 0.879

actggcagcggccctggcagcgtcccaggcagcgtcccaggcagcggccctggcagcggc	CRISPR spacer
actggcagcggccctggcagcgtcccaggcagcgtcccaggcagcggcactggcatcggc	Protospacer
************************************************ ****** ****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	MN304817	Phage 68_12, complete genome	24922-24951	0	1.0
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	MN304817	Phage 68_12, complete genome	25042-25071	0	1.0
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	MN304817	Phage 68_12, complete genome	24862-24891	0	1.0
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	MN304817	Phage 68_12, complete genome	24910-24939	0	1.0
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	MN304817	Phage 68_12, complete genome	24862-24891	1	0.967
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	MN304817	Phage 68_12, complete genome	24874-24903	1	0.967
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	MN304817	Phage 68_12, complete genome	24910-24939	1	0.967
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	MN304817	Phage 68_12, complete genome	24982-25011	1	0.967
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	MN304817	Phage 68_12, complete genome	24994-25023	1	0.967
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	MN304817	Phage 68_12, complete genome	25054-25083	1	0.967
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	MN304817	Phage 68_12, complete genome	24850-24879	1	0.967
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	MN304817	Phage 68_12, complete genome	24922-24951	1	0.967
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	MN304817	Phage 68_12, complete genome	24970-24999	1	0.967
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	MN304817	Phage 68_12, complete genome	25042-25071	1	0.967
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	MN304817	Phage 68_12, complete genome	24850-24879	2	0.933
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	MN304817	Phage 68_12, complete genome	24934-24963	2	0.933
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	MN304817	Phage 68_12, complete genome	24970-24999	2	0.933
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	MN304817	Phage 68_12, complete genome	25006-25035	2	0.933
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	MN304817	Phage 68_12, complete genome	24874-24903	2	0.933
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	MN304817	Phage 68_12, complete genome	24898-24927	2	0.933
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	MN304817	Phage 68_12, complete genome	24958-24987	2	0.933
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	MN304817	Phage 68_12, complete genome	24982-25011	2	0.933
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	MN304817	Phage 68_12, complete genome	24994-25023	2	0.933
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	MN304817	Phage 68_12, complete genome	25030-25059	2	0.933
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	MN304817	Phage 68_12, complete genome	25054-25083	2	0.933
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	KR011061	Skermania phage SPI1, complete genome	42358-42387	3	0.9
NC_018828_6	6.1|3327819|26|NC_018828|CRISPRCasFinder	3327819-3327844	26	NZ_CP045303	Azotobacter salinestris strain KACC 13899 plasmid unnamed1, complete sequence	2437-2462	3	0.885
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	NZ_CP025188	Roseomonas mucosa strain AD2 plasmid p1-AD2, complete sequence	965-994	6	0.8
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	NZ_CP025188	Roseomonas mucosa strain AD2 plasmid p1-AD2, complete sequence	965-994	6	0.8
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	MN304817	Phage 68_12, complete genome	25066-25095	7	0.767
NC_018828_4	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	NZ_CP015733	Arthrobacter sp. U41 plasmid unnamed1, complete sequence	82065-82094	7	0.767
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	MN304817	Phage 68_12, complete genome	25066-25095	7	0.767
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	MN304817	Phage 68_12, complete genome	24838-24867	7	0.767
NC_018828_4	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	NZ_CP015733	Arthrobacter sp. U41 plasmid unnamed1, complete sequence	82065-82094	7	0.767

1. spacer 4.1|2259073|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 0, identity: 1.0

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

2. spacer 4.1|2259073|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 0, identity: 1.0

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

3. spacer 4.5|2259337|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 0, identity: 1.0

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

4. spacer 4.5|2259337|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 0, identity: 1.0

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

5. spacer 4.1|2259073|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 1, identity: 0.967

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

6. spacer 4.1|2259073|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 1, identity: 0.967

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcggcccaggcagcgtcccaggc	Protospacer
********** *******************

7. spacer 4.1|2259073|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 1, identity: 0.967

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

8. spacer 4.1|2259073|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 1, identity: 0.967

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcggcccaggc	Protospacer
********************** *******

9. spacer 4.1|2259073|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 1, identity: 0.967

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtccctggcagcgtcccaggc	Protospacer
************** ***************

10. spacer 4.1|2259073|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 1, identity: 0.967

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtccctggcagcgtcccaggc	Protospacer
************** ***************

11. spacer 4.5|2259337|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 1, identity: 0.967

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtccccggc	Protospacer
************************** ***

12. spacer 4.5|2259337|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 1, identity: 0.967

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

13. spacer 4.5|2259337|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 1, identity: 0.967

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcggcccaggcagcgtcccaggc	Protospacer
********** *******************

14. spacer 4.5|2259337|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 1, identity: 0.967

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

15. spacer 4.1|2259073|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 2, identity: 0.933

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtccccggc	Protospacer
** *********************** ***

16. spacer 4.1|2259073|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 2, identity: 0.933

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcggccctggcagcgtcccaggc	Protospacer
********** *** ***************

17. spacer 4.1|2259073|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 2, identity: 0.933

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcggcccaggcagcgtcccaggc	Protospacer
** ******* *******************

18. spacer 4.1|2259073|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 2, identity: 0.933

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtccctggcagcgtccctggc	Protospacer
************** *********** ***

19. spacer 4.5|2259337|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 2, identity: 0.933

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcggcccaggcagcgtcccaggc	Protospacer
** ******* *******************

20. spacer 4.5|2259337|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 2, identity: 0.933

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcggccctggc	Protospacer
********************** *** ***

21. spacer 4.5|2259337|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 2, identity: 0.933

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcggccctggc	Protospacer
********************** *** ***

22. spacer 4.5|2259337|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 2, identity: 0.933

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcggcccaggc	Protospacer
** ******************* *******

23. spacer 4.5|2259337|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 2, identity: 0.933

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtccctggcagcgtcccaggc	Protospacer
** *********** ***************

24. spacer 4.5|2259337|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 2, identity: 0.933

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcggccctggc	Protospacer
********************** *** ***

25. spacer 4.5|2259337|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 2, identity: 0.933

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtccctggcagcgtcccaggc	Protospacer
** *********** ***************

26. spacer 4.5|2259337|30|NC_018828|CRT matches to KR011061 (Skermania phage SPI1, complete genome) position: , mismatch: 3, identity: 0.9

ccaggcagcgtcccaggcagcgtcccaggc-	CRISPR spacer
ccaggcggcgtcccaggcggcgt-ccaggcg	Protospacer
******.***********.**** ****** 

27. spacer 6.1|3327819|26|NC_018828|CRISPRCasFinder matches to NZ_CP045303 (Azotobacter salinestris strain KACC 13899 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.885

gtcttggcaggccagcgggacggggt	CRISPR spacer
gtcctggcaggccagcgggatgggtt	Protospacer
***.****************.*** *

28. spacer 4.1|2259073|30|NC_018828|CRT matches to NZ_CP025188 (Roseomonas mucosa strain AD2 plasmid p1-AD2, complete sequence) position: , mismatch: 6, identity: 0.8

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
gtgtgcggcgtcccaggcagcgtccccggc	Protospacer
 .  **.******************* ***

29. spacer 4.5|2259337|30|NC_018828|CRT matches to NZ_CP025188 (Roseomonas mucosa strain AD2 plasmid p1-AD2, complete sequence) position: , mismatch: 6, identity: 0.8

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
gtgtgcggcgtcccaggcagcgtccccggc	Protospacer
 .. **.******************* ***

30. spacer 4.1|2259073|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 7, identity: 0.767

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ctgcagagcgtccctggcagcgtccctggc	Protospacer
*.  . ******** *********** ***

31. spacer 4.1|2259073|30|NC_018828|CRT matches to NZ_CP015733 (Arthrobacter sp. U41 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccgcgcagcgtcccatgcagcgtcctgcgt	Protospacer
**  *********** *********.. *.

32. spacer 4.5|2259337|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 7, identity: 0.767

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ctgcagagcgtccctggcagcgtccctggc	Protospacer
*.. . ******** *********** ***

33. spacer 4.5|2259337|30|NC_018828|CRT matches to MN304817 (Phage 68_12, complete genome) position: , mismatch: 7, identity: 0.767

ccaggcagcgtcccaggcagcgtcccaggc---	CRISPR spacer
ccaggcagcgtccccggcagca---cgtgcctt	Protospacer
************** ******.   *. **   

34. spacer 4.5|2259337|30|NC_018828|CRT matches to NZ_CP015733 (Arthrobacter sp. U41 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccgcgcagcgtcccatgcagcgtcctgcgt	Protospacer
**. *********** *********.. *.

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1715779 : 1774980	66	Bordetella_phage(45.45%)	protease,tRNA,head,tail,terminase,transposase	NA
DBSCAN-SWA_2	1783207 : 1787019	7	Bordetella_phage(83.33%)	NA	NA
DBSCAN-SWA_3	2253901 : 2260898	12	Acinetobacter_phage(14.29%)	integrase	attL 2242819:2242833|attR 2266920:2266934
DBSCAN-SWA_4	2266104 : 2288773	29	Pseudomonas_phage(17.39%)	tail,terminase	NA
DBSCAN-SWA_5	2298072 : 2306530	7	Lake_Baikal_phage(16.67%)	protease,transposase	NA
DBSCAN-SWA_6	2975524 : 2982984	8	uncultured_Mediterranean_phage(33.33%)	tRNA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_018828|1715779:1774980|DBSCAN-SWA
GTCAGCCTACGACGTTGACCAGCTTGCCCGGCACGACGATGACGCGCTTGGGCGGACGGCCTTCGAGAAAGCGCGCCACTTCTTCCTGGGCGGCGGCGATGCGCTCGATGTCTTCCTTGGGCGCCTTGGCGGCAACCCGGATCGAGCCGCGCAGCTTGCCGTTGACCTGCAGCATCAGCTCGATCTCGTCGGCCACCAGGGCGGCCTCGTCGACGTGCGGCCAGGGCGCGTCCAGCAGGTCGCCCAGGTGCTCGGCGTAGCCGAGATCCTGCCACAGGTGCCAGGTGATGTGCGGCACCACGGGGTACAGCACGCGCAGCAGCAGGCCGAGGGTCTCGGCGCGCGCGGCATCGGCGGCGGGGCCTTCGGGCAGGGGCGCGTCGTCGATGGCATTGAGCATTTTCATGCAGGCCGACACGACCGTGTTGTACTGGATGCGCTGGTAGTCGTAGTCGGCCTGCTTGAGCAGCCCGTAGACCTCGCGGCGCAATTCCTTGACGGGGGCCGGGGCCTGCGCCCAGTCGGCGCCGGTGGCCAGGCCGCGGCCGACCGCCTCGCGCTGCGCGTAGCCCAGCGCCCACAGGCGGCGCAGGAAGCGGTTGGCGCCCTCTACCCCGGAGTCGGACCATTCGAGCGTCTGCTCGGGCGGGCTGGCGAACATGACGAACAGCCGCGCCGTGTCGGCGCCCAGGGTGTCGATCAGCGACTGCGGGTCGACGCCGTTGTTCTTAGACTTGGACATCGTGCCCACGCCGCCGTAATTCACTTCGGAGCCGTCGCGCTGGAGCTTGGCGCCGACGATGGCGCCCTTGGCGTCGTAGACGTTGTCGACTTCCTCGGGCCAGAAGTATTCGATGCCGCCCTGCGGCGTCTTGCGCGAGTAAATGTGGTTCAGCACCATGCCCTGGCACAGCAGCTTGGTGAAGGGCTCGTCGAAGTTGAGCAGGCCCAGGTCGCGCATGACCTTGGTCCAGAAGCGCGCGTACAGCAGGTGCAGCACCGCGTGCTCGATGCCGCCGATGTACTGGTCCATCGGCATCCAGTAATCGTTGCGGGCGTCGACCATGGCCTGGTCGTTGTCCGGCGACGTGTAGCGCATGAAGTACCAGGACGAGTCCACGAAGGTGTCCATGGTGTCGGTTTCGCGGCGCGCGGGCTTGCCGCAGCGCGGGCACGAGCACGACAGGAAGGCTTCGTTCTTGGCCAGCGGGTTGCCCGAGCCGTCCGGGATGAGGTCGTCGGGCAGCACCACGGGCAGGTCCTGCTCGGGCACGGGCACCGGGCCGCAATCGGCGCAGTGGATGATGGGGATGGGCGTGCCCCAGTAGCGCTGGCGCGAAATGCCCCAGTCGCGCAGGCGCCAGGTGGTCTGTTTCTCGCCCAGACCCTGGGCCGCCAGGTCGGCGGCGATGGTGTCCACGGCGGCCTGGTAGGCCAGGCCGTCATATTTTCCGGAGTTGACGGTGCGGCCGGCCTGCTTGTCGCCGTACCATTCCTGCCAGGCGTCGGTGGAGTAGGTCTTGCCTTCCAGCGCGACGACCTGGCGGATCGGCAGGCCGTACTTGCGCGCGAAGGCGAAATCGCGCTCGTCGTGCGCCGGCACGCCCATCACGGCGCCGTCGCCGTAGGTCATCAGCACGTAGTTGCCGACCCAGACGTCGATTTCCGCGCCGGTCAGCGGGTGGGTGACGGTCAGGCCCGTGGGCATACCTTCCTTTTCGCGCGTGGCCATCTCGGCCTCGGTGGTGCCGCCCAGCTTGCATTGCTCGACGAAGGCGGCCAGCGCCGGATTGGACTGCGCGGCATGGGTGGCCAGCGGGTGCTCGGGCGCCACCGCGCAGAACGTCACGCCCATGATGGTGTCGGCGCGGGTGGTGAACACATACAGCTTGCCGTCCTGGATCAGCTTGCCGTCGGCGCCGGCGATGCGGTGCGGGAAGGCGAAGCGCAGGCCCTCGGACTTGCCGATCCAGTTCTCCTGCATCAGGCGCACGCGCTCGGGCCAGCCCGGCAGGTTGGTGCTCACCTGGTCCAGCAGTTCTTCGGCGTAATCGGTGATGCGCAGGTAGTAGCCGGGGATCTCGCGCTTTTCGACCGGGGCGCCCGAGCGCCAGCCGCGCCCGTCGATGACCTGTTCGTTGGCCAGCACCGTCTGGTCGACCGGATCCCAGTTGACGACCTGGGTCTTGCGGTAGGCGATGCCTTTTTCCAGCATCTTCAGGAACAGCCACTGGTTCCACTTGTAATACTTCGGGTCGCAGGCGCACATTTCGCGCGACCAGTCGATGGCCAAGCCCATCGCCTTCATCTGCTTCTTCATGTAGGCGATGTTGTCGTAGGTCCACTTGGCCGGCGGTACCTTGGACTTGATGGCGGCGTTCTCGGCGGGCATGCCGAAGGCGTCCCAGCCCATCGGCATCAGCACGTTGTAGCCGCGCATGCGCAGCTGGCGCGCCATCATGTCGTTGATGGTGTAGTTGCGCACGTGTCCCATGTGCAGCTTGCCGCTGGGGTAGGGCAGCATGGAGCAGGCGTAGAACTTGGGTTTTTCCGACCCGTCGGGGTTCTTGGCGTGCTCGTGCACCAGATAGGCATCGCGGGCCTGCCAGGTTTGCTGGGCGGCTGCTTCGACGGAGTTGGGTTGGTAGCGTTCCTGCATGGACTCGTGCGAAAAAATAGGTAACGGACCGCGCCCGGCAGGGCGCGGGCGGTCAAAACCATTGATTATAGGAGGTGCTAGGCGATCGCAGGGGCCGGCGTGGTTTCCGGGATGCGCGCCGACCGCGCCAGGCACCCGTACAGCAGGGCTGCCAGCGAGGTCAGCGCGCCGGCCGCCGTGACGCCCAGCCAGCCGGCGTGGGCGTAGATCCAGGCCGACAGCAGCGATCCCGCCGCGCCGCCCAGGAAATACGAGGTCATGTAGCCGGCGGTCAGGCGGCTGCGCGCCTCGGGCCGCAGGCGATAGATGGCGCTCTGGTTGGTGACATGGACCGCCTGGATCGCCAGGTCCAGGGCCAGTACGCCGGCCAGCAGGGGCGCGACGTGGTGGGCGCCCCAGGCCAGCAGCGGCCACGAGGCCAGCAGCATCAGGATGGCGGCCACCCAGTAGACGGTGCGCCAGCTGCCGAGATCGGCCAGCGCGCCGGCGATGGTGCGCGCCAGCAGAATGCCCAGCAGCAGGCCGCTCATGACCGCCCCGACCACTTTGCCGCGTTCGTGCGGTTCGGCCAGGGTGGCGGCAAACGGCACCAGGACCTGCGCCACGACGGACAGCAGGCCGGTCACGGCGGTGCCCAGCATGAGCCAGCCGATGCCGGGCGAGAAGGCCGACAGCAGCAGGCCCACGGCCGACAGGGCGGTCATCAGCGCGATCAGGGTGCGCCGCTCGTAGAGGTCGCCCAGCGGCACCAGCAGGATCAGGCCCACGGCATAGCTGAGCTGGGCCACCGTGACGATGGCGCCGGCGGTGGCGGTGGTGAGGGCGAATTCGGCGCCGATGGTATGCAGCAGCGGCTGGGCGTAATAGTTGCTGGCCACGGCCAGGCCGGTGGCCACGGACATCAGCAGGACGATGGGCGCGGTCAGGCGCGCGCGCGCGGGGCTCATTGCGGGATGCCTCCCGGCGTCGTGCGGTCGTGTTCGGCCAGCAGGCGCTTGAGCAGGCCCGCCAGCTGGCGGCGCTCGGTGGCCGACAGGGGCGTCAACAGGGCGTCGATTGCCTCCAGGTAGTCGGCCAGGATCTGCTGGATAGTGCGCAGGCCCGCGGGCGTGAGCGAGACGATGACGCCGCGCCGGTCGTCCGGGTTGGGGCTGCGCGCGATCAGGCCGCCCTGTTCGAGTTGATCGAGCCGGTGCGTCATGGCGCCGGAGGAAAGCAGCAGGGCAGCGGTCAGTTGCTGCGGCGACAACGCATGCGGGGCGCCTGCGCGATACAGCGTGGCCAGCAGGTCGAACTGTCCCTGGTGCAGGCCGGCGGCGCGAAACAGCGGCTCGATGCGCCGCAGCGTGGCGGTATTGAACCGGAAAATACGCGCCAGCACGCCATGGACGAGACGTCCAGGTCGGGGCGTTCGTGCGCCCATTGGGACAGCACCAGGTCGACGTGGTCTTTCATTATTGTCTTGATATCAAGTATCTTTATATCAAGATAAATACGGCCCGGTCAAATCGCGACTGCATAAACGAAGAGCCCGCCGGTGCGGCGGGCTCTGCGGTTTGACCTGAGACGTCAGGCGCTTATTGCGCGGCGTCCTTCAGCTTCTTCAGGGGACGAACCTTGACCTTCACCGAGGCGGGCTTGGCCGGGAACCAGCGCTCTTCGCCGGTGAACGGGTCCTTGCCGAAGCGCTTGGCCTTGGCGGGAACCTTCTGCACGGCGACCTTGAACAGGCCGGGCAGGGTGAATTCGCCAGCGCCCTTCTTGTCGACCGAGGCGAGCACCGAGCTTTCCAGGCCAGCCAGCACGGCCTTGACCGACTTGGCTTCCACGCCGGTGTTCTCGACCAGGTAGGCGATCAGTTGCGACTTGTTCAGCGCTTCCTTGATGGGGCGCACTGCGGCGGCCGTTTTCTTCACGGCGGGTTTGGCGGGAGCCTTCTTGGCGGGAGCCTTGGCAGGAGTCTTGGCAGGAGTCTTGGCGGCGGTCTTCGTGACTTTCTTGGCAGGCGCTTTTGCTTTGGTAGCCATGGTCAAAATCCGTAGTAGTGAGGATATGGAGGCAGCGTGTTCGCCGGATATTCGATGAACAACACCTCGCGCCCGATGATAGCGGAAACTCGCGCCGCTGCATGCGTTCAGCGCCGCGCAGAGGTACAGGTTGTTGTTTTCAGCGCAACGAATGCGTGCCGACGCTGGTTTTCCCTAGCCGCGCGGCGGGTGTGCGGCGATGCGCGCGCGCACCTCCGAACCCTTCGTGGACGATGCGCGCGGGCAGCCGGGCAGGGCGCGTGGCGATGGCGCGCCCAATCCCGGATGTTCTGGCGCCAGGATCGGAAAGCGCCGTGGCAAACACAGGAGTCGCCCGCGCGTTGCGCGTGCGCGGCCATGGGTTTACGCTAGCGCCTTTTGACGCGACAGCGGGCGCAAGCGGCCGTGGCGCGGGATACAAGGTCAACAAGATGGGGAAGACAGTACGCGGCGGCGCGGCCGCAATCCTGGGCGGCTGGGTCAACGACATCACGCCCGGCACGCTGCGCGCGGATGCGCAGGCCGGTTTGCTGGGGGCGCTGCTGGTGCTGCCGCAAGGGGTGGCCTTCGCCATGCTGGCCGGCCTGCCGCCCGAATACGGGCTTTATTCGGCCATCGTGCCCTGTATCGTCGCGGCGCTGTTCGGCTCCAGCCGGCATGTGCTGTCCGGCCCGACCAACGCCAACTCGCTGGCGCTGTTCGCCGTGCTGGCGCCCTTGGCGCTGCCGGGCAGCCCCGGTTATATCCAGATGGCGCTGGCGGTCACCATCCTGGTCGGGGTGATGCAGCTGGCGGTCGGGCTGCTGCGGCTGGGCTCGCTGGCCAATTTCATTTCACCCTCGGCGCTGTTTGGCTTCACCAGCGGGGCGGCGCTGCTGATCGCCGTGCACGCGCTCAAGGATGCGCTCGGGCTGGAAGGCGTGCAGGCGCACTCCGCCGGCGCGGTCCTGGCGGCAGTGGGCAGCCGGCTGGGCGAGGCGCACTGGGGCGCCAGCGCGGTCGCGCTGACGACCATCATCGTGACGCTGCTGGTGCGGCATTGGGATCGCCGCAAGCCGCACATGCTGGCCGGCCTGGCGGCCGGCACGCTGCTGGCGGCCGCGCTCAACGCCGGCGTGTTCGCCGCGGCGGGCCAGCCGATTTCGGTGCTTGGCGCCCTGGCGCAGCCGTGGCCGCCGTTTCATGTGCCGGCCGTGCAATGGAGCGTGCTGCCTGATCTGGTGGGCGTGGCGGTGTCGCTGACCATCGTCGCGCTGGCGCAATCCATCTCGATCGCCAAGGCGGTCGCGATGCGCTCCGGCCAGTTGATAGACGCCAACCGCGAGTTCATCGGCCAGGGCTTGTCCAATGTCGTGGGCGGACTGTTCTCGTCGTACCTGTCATGTGGTTCGCTGAACCGTTCGGTGCCGAACTACGAGGCGGGCGCGCGCACGCCGATGGCGGCGGTGTTCGCGGCCTTGCTGCTGGTCTTGCTGGTGCTGGTCAGCAGCCCGGTGCTGGCGCTGATTCCGCACGCGGCCATCGCCGGCCTGCTGATCGTGGTGGCCTGGTCGCTGCTGGACCTGCCGCGCTGGAGCGTGCTGGTGCGCATCGCGCCGCGCGAGGCGCTGATCGCTGCGGCGACGCTGGCGGCCACCGTGACGATCCGCATGGAGATCGCCATCCTGCTGGGCACGCTGCTGTCGCTGACTGCCTACCTGTACCGCACGGCGCGGCCCGCCATGCGTCCGATGGGCTTCGATGCCGCCGATCCGCAGCGCCATTTCGCGGTGCTGGAAGGGCAGCCCGGCGAATTGCCGGAATGCCCCCAGCTGAAACTGTTGCGCATGGAGGGGTCGGTGTATTTCGGCGCGGCCACGCATGTCACCGACCGCCTGCAGGCGCTGCGCGCCGGGGCGAGCGCCGGACAGCGCCACCTGCTGGTGATGAGCAAGAGCATGAACTTCATCGACCATGCCGGCGCGCAGGTCTGGGAGGAAGAATTGCGCAGGCGGCGGGCGGGCGGCGGCGATCTGTATTTCCACCGGCCGCGCCCCGAGGTGCTGCGCGACTGGCGCCGCTCGGGCTTCATCGACCGCCTCGGCGCCGACCACATCTTCCCCGACAAGGCGACCGCCATACATACCATTTACGAGCGGCTGGATCCGGAGATCTGCCGCGGCTGTACGGCGCGCATCTTTACGGAGTGCGGCCCGCCGGGCACGGCGCACCAGCCCAGCGCCGAGCGCGACGAATGAGCCGGCCCGCCGGGCCGGGGCCTGCCACGGCGGGCCTTGCCAAATAAAACGGCCCCGCCAGGGCGGGGCCGTTCACCATGGCGCGCGCACGCGCCATGCCAACGCAAGCCGAATTACTTCAGCTTGGTCTCTTTGTAGTCGACATGCTTGCGAGCGACGGGATCAAATTTCTTGATCAGCATCTTTTCGGGCATGTTGCGCTTGTTCTTGGTGGTCGTGTAGAAGTGGCCCGTGCCGGCAGTCGACTCGAGCTTGATCTTTTCGCGGATACCTTTGGCCATGTCGTGCTCCTGGGGTGTAGTGTTGGCGGCTAATGTCTAGGGGACTGGGGGCGGTAGCCCTGCTCAGACCGCTTCGCCGCGGGCACGCAGGTCGGCCAGGACGGCGTCGATGCCGTTCTTGTCGATCGTGCGGATGGCTTTTGCCGTCACGCGCAGGCGCACCCAGCGGTTTTCGCTTTCGACCCAGAACCGGCGCGATTGCAGGTTGGGCAGGAAGCGGCGCTTGGTTTTGTTGTTCGCGTGCGAAACATTGTTGCCCACCATCGGGCCTTTACCGGTCACTTGGCATACGCGTGCCATGGATGCACCTCTCAGGGTTGTTCTAGTCCGCGGCGCGTCGGGAATCGGTGACCGGGTATTTGCCGCAAGGTGCTGCGCCGTGGCCTGCGGCCGACTAGACGCCCGGGGCAGGACCCCGGCCTTGCCACCCAGTATCTGGATGGGGTCCGCGAGATGGCCGATCCGGCGCCTGCCGCGTCGCGGGGTTGAACCACCGAAACGCGTGCGGCAAGCCGTAAGCCACCTCAGGACCTGTGCTTATACCCCGTTGCCTATCCCGCGTGTGTTCACTGCGAGACGCAAATTATGCACACGGCCACAAAGCATAGTAACCGTGCACGGGAAACTTCAAGTCAAGACGGCAAGTCTACTACGAAAACCCAAGGAAAATCAAGCAGGTCTGCGCGCCATGCGGCCGAACTGCCACGACAGGCAGGCCGAGCCGGCCAGCACCGCGGCCAGCGGCAGCACGCTTTCGGCCGGCCAGATGCTGATGATCAGCCCGGCCAGCGCGCCACAGGACAGCTGCAGCGTACCCAGCAGGGCCGATGCCGCGCCCAGGCGCCGGCCCTGTTCCGCCAGCGCCAGGGCGGCCGAGTTGGGGTTGACGAAGCCCTGGCTGAACATATAGCCCATCAGGCAGGCCATCAGCAGCGGCAGGCTCATCAGCCCGAGCAGGGCCAGGGCCAGGGCGCTCAGGCTGGCCACCGCCAGCGCGACCTGGGCGTGCCGCTGCAGGGTGGCCGGCGCGGACTTGCGCAACAGCCGGGCGCTGATCTGCGAGCCGACGATCAGCGCGGCCGCGTTGGCGCCGAACAGCAGGCCGTAATACTGGGGCGCTATGCCGTACAGCTCGATGAAAATGCGCGGCGAGCCGACGATGTAAGCGAACATGCCCGCCTGGCCCATGCCGCCCGCCAGGCTATGGCCCATGAAGCCGCGGTGCGCCAGCAGCGCGCGGTAATTGCTCAGGATGGTGCCTGCCCGCAGCGGCAACACGCGCTCGGGAGCCAGCGTCTCCTTCATCGTCAGCGCCACGGCCAGCAGCAGCGCCAGGCCGCCGGCGGCCATCAGCCAGAAAAGGCTGCGCCAGCCGACGAAAGCGAGCAATTGCGCGCCGGCCAGCGGCGCCAGGATCGGCGCCAGGCCCATGATCAGCATCAGCAGCGACATGGCGCGCGCGGCTTCCTGGGTTTCGTAGTGGTCGCGGATCACCGCGCGCGGGATGACGACGCCGGCCGCGCCGCCCAGGGCCTGGGCCACCCGCCACGCCGTCAGGGTCTGGATGTCGCCGGCCAGCGCACAGCCCAGCGAGGCCAGCACGTACAGGATGAGCCCGCCCATCATGGGCAGCTTGCGGCCGTAGCGGTCGGCCAGCGGGCCATAGATGATCTGCGCCCCGGCCATGCCGATCAGGTATGCCGCCAGGGTCCGCTCGACTTCGCCGCGTTCGACGCCCAGGCCGGCGGCGATCGACGGAAACGCCGGCAGGTACATGTCGATGGAGAAGGGGCCGATGGCGGTCAGCGCACCCATGAGGATGAGCCAGCCCGGCATGCTGCGGGAAATGGTTTGCGGGGGCATGGGAGGGGCGGTGCGCGGCGACGGCGTACAGGGCCGTGCGAGCGTTATTGCATGGTCTGAGGCAAGCCGGTCACTGTATCACGGCCAGGCTTGCGTTTGAATTGCAACTGTTTTCCGATAAAGTCTGCGTGTCCGTTCATATTCAGGGGAGAGGAAGTCGTGAATCCTTTGCTGTCTGTGGTGGAACGCAAGCTCCAGGAATTGCCGGTACCGGTGCAATTGACCCTGCCCGATGGCACGGTCTTGGGCAGTCCCGAGGCGCGCGTGCGCTTCGTGGCGCGGGACAAGACCGCGCTGGCCCACCTGGCCGAGGGCGCCGTCGGCGTGCTGGGCCAGGACTACGTCGAGGGCCGCATCGATATCCAGGGCAGCATGCGTGATGTGATGGCGGCCGCCGCGGCGCTGCTGCCCAGTTCGCCGGTCGACGCGGCGCGCGGCGGCTGGCTGACCGAGCTGGTGCGCAAGGTTACCTCGGTGTGGCGCCACTCGATCGAGCGCGATGCGCGCCAGATCGAGTTCCACTACGACCTCTCGGACGATTTCTATGCCCTGTGGCTGGATCCGCGCCGGGTCTATTCCTGCGCCTATTACCGCACGCCCGACATGACGCTGGCGCAGGCCCAGGAAGCCAAGCTGGACCATATCTGCCGCAAGCTGCGGCTGCAGCCGGGCGAGCGTTTCCTGGACGTCGGCGCGGGCTGGGGCGGGTTGCTGCTGTGGGCGGCCGAGAACTACGACGTCGATGCCACCGGCATCACGCTATCGCGCAACCAGCATGCCTATGTCAACCGCCTGATCGAGGAAAAAGGCCTGTCGGGGCGGGTGCGCATGGAGCTGCTCGACTACCGCAAGCTGGACGAAGGCGCGCCGTACGACAAGATCGCCTCGGTGGGCATGTTCGAGCACGTCGGGCGCGCCCAGCTGCCGGGCTATTTCGCCAAGCTGCGCCGGCTGGTCAAGCCGGGCGGACTGGTCATGAACCATGGCATTACCGCGGGCGGCGTCTACAACGCCGAGCTCGGCAACGGCATGGGCGAATTCATCGAGAAGTACATCTTCCCGGGCGGCGAGCTCACGCATATCAGCAGCGTGCTGGAGGCGGTGACGGCGGGCGGCCTGGAAGCCGTCGACGACGAGAACCTGCGCCCGCACTACGCGCGTACGCTGTGGGCCTGGAGCGACGCGCTGGAAGCATGCCTGCCCGAGGCCGCGCGCATCCTGCAGGGAGAGCAGGGCGAGCGTTCGCTGCGCGCCTACCGGCTGTACCTGGCCGGCTGCGCGATGGGGTTCGAGCACGGCTGGATTTCCCTGCACCAGGTGCTGGTCACGACCCCGGCCACGGGCCGCACCGACGAGCTCGACATGGCCCGGGACCTGGCCTATCCGTGGCGGCGCGATTACATCTACGCCGGCAACGCCCGCTAGGATGCGGCCGGCCCCGGCGCCATGCGCCGGGGCCGGCCGTCGCAAATCATTTCATCTCCAATTGAAACCAAATAATTCGACGCCGTGCTGCGCCGCAACACGGCGCGTACACTGGTTTTGCGCCTCACGCCTAGGGGCTTTCCCCGACGCCCGAACAGGGTGAATGTATCTGTTTACTTCGGTCCTGGGGTTGGTCGAGGATTCAAAATCGTCTAAGATGCGGCCTTCTTCGTTTAGTTTCTTTCAATTTTCTGCGAGCCTTGTACCGGCAACTTCGCCGGTGACCAGGCCGCTGTCTTACAGGATGGCCCCAGCCCGCGGCGCGGCCTCCTGCTGCTAGTGTCGGTTTGTATTGGCGGTTCTGCCCGTCTTCCGCACAACCCCCTTAGCTCCACGGCATGGTCCGGCGTCTGCCCGGTCCCGTGTCCCTGACCTATGGAGGCAAAAGCCAATGCGTTTCACCCCAGTAAAGACCCTGGCCGCCCTGGCCGCACTCTGCGCGTTCAGCGGTGCGGCCCAGGCAGCCGACCAGCCCCAGTGCGAAGTCTCGCGGCCCGTCAATTTCGGCGGCATGAATTGGGAATCCAACCTCGTCCTCGTCGACATCGAGCGCTTCATCATGGAAAAGGGCTATGGCTGCAAGACCGAGGTCTTGCCTACCGAGACCCTGCCGGCGCTGGCCGCCCTGGAGCGCGGCGACCTCGACATCAATACCGAAATCTGGCTCAACAGCGTTGCCGACCCTTGGGACCGCGCCCAGAAGACCGGCAAGGTCAAGCGGGTGGGCGAGCTCTACATGGGCGGCGAAGCCTGGTTCGTTCCGCGCTACACCGCCGAGCGCCTGCCCGAGCTGAAGTCGGCGGCCGACCTGCCCAAGTTCAAGGACCGTTTCAAGGACCCCGAGGAGCCCGGCAAGGGGCGCTTCTATGGTTGTCCGGCGGGCTGGGGCTGCGAAGTGACCAGCACCAACCTGTTCCATGCGCTCAAGCTGGATGACAGCTACACGCTGTATTCGCCCGGCACCGGCGCGGCGCAGAAGGCGGCCCTGATGTCCGCCTACAAGCGCAAGCAGGACGTGGTGTTCTACTACTGGTATCCCACGCCGCTGGTCGGCTCGATGGATCTGGTCAAGCTGGAACTGCCGCCGTACGATGCGGAAAAGCACAAGTGCCTGACGGCGCCCAAATGCAGCGATCCGCAGCCTAGCGCCTATCCCGAGAACCCGGTGTTCACCGCTGTGAATACTCGGTTCTCGGAAGAGGCGCCCAAGCTGACCGAGTTCCTGTCCAAGGTGGCGGTGCCGCTGCCGGTCATGGACCAGACCCTGGCCCACATGGAAGAGTCCGGCGACGAGTCCGGCGCCGTGGCGCAGTGGTTCCTGAAGAACCAGGCCGACGTCTGGAAGAAGTGGGTGCCGGCCGACGTGGCCGAGCGTGTCCAGACCGCCCTGTAGCGGTCCAGGGCCACGATGGCGCCATTGCGCCGCCGTGGCCCGCGATGGCGCCCGACGGGGGCGCCGATCGCGCCCGGCGCGGCCATAGGCCCCGGGCATCCCGTGTCGCCGGCCCCGTACGCCGGAGCGGCCCTTTCCTGGGCCGCGCGACACGCCAGAATGGAGTCGCCTGATGTTCCCTGAAGTCATTCCCGCGCGCGCAGTGCGCGGGGCCATCGACGGATTCGTCGATCATCTCGTTACCAACTACGCCGACACGCTGGAAGCGATGTCGCAACCTTTCCTGAGCGTGCTGGTCTGGCTGGAGCAGGTGCTGCGCCAGTCGCCGTGGTGGGCGGTGGTGGCGGTCACCATCGCCATCGCGTGGCTGGTCAGCCGCCGCATCGGCCTGAGCCTGGCCATGGGCGCGCTGCTGTGCGTCATCGGCGTGCTGGGCCTGTGGGACGCCGGCATGCAGACGCTGGCGCTCATGATCATGGCCGCCGGCCTTTCGGTGGTGATCGGCATCCCGCTGGGCGTGCTGATGGCGCGGGTGGACTGGCTGCGCGCCGGCATGCTGCCGGTGCTGGACGTGATGCAGACCATGCCCAGCTTCGTGTACCTGATCCCGGTCGTGATGCTGTTCGGGCTGGGCAAGATCCCGGCCATCATCGCGACCGTGATCTACGCCGTGCCGCCGCTGATCCGCCTGACCGACCTGGGTATCCGCCTGGTCGACCGCGAAGTCCTGGAGGCGGCGCGCGCCTTCGGCGCCAATCCGCGCCAGCAGCTGTTCGGCGTGCAGTTGCCGCTGGCCCTGCCCAACATCATGGCCGGGATCAACCAGACCACCATGATGGCGCTGTCGATGGTGGTCATCGCTTCGATGATCGGTGCGCGCGGCCTGGGCTATGAAGTGCTGCTGGGCATCAACCGCCTGGAGGTCGGCCGCGGACTGCTGGCCGGGCTGGGCATCGTCGTGCTGGCGGTGCTGTTCGACCGCATCACGCAATCGTACGGGCAACGCGTACGCACGGGAGGCCAGCGATGAGCAAAATCGAAGTCAAGAATATCTACAAGATCTTCGGCCCGCATCCCGGCAAGTGGCTGCAGGCCGCCCGCGACGGCATCAGCAAGGAAGACCTGCTGGCCAAAAGCGGCCACACGCTGGGCCTGCGCGACATCAGCCTGTCCATCGAGGAAGGCAGCATCTACGTGATCATGGGGCTGTCGGGGTCGGGCAAGTCGACGCTCATCCGCCACTTCAACCGCCTGATCGAGCCCAGCGCCGGCCATATCCTGGTCGATGGCGTGGATGTGGTCAGCCTGAACAAGCGCGACCTGGAGACGTTCCGCCAGAAGAAGATGAGCATGGTCTTCCAGCGCTTTGGCCTGTTCCCCTACCGCACGGTGCTGGACAACGCCGGCTACGGGCTGGCGGTGCAGGGCGTGGCGCGCGCCGAGCGCGAGCAGCGGGCCCGCCATTGGCTCGACCAGGTAGGCCTGTCCGGCTTCGAGAACCAGTATCCCCACCAGTTGTCGGGCGGGATGCAGCAGCGCGTGGGGTTGGCGCGGGCGCTGGCCACCGACGCCGAGATCCTGTTGATGGACGAAGCCTTCTCGGCCCTGGACCCGCTGATCCGCCGCGAGATGCAGGACCACCTTCTGCAGCTGCAGGCCAAGCTGAACAAGACCATCGTGTTCATCACGCACGACCTGGACGAGGCGCTGCGCCTGGGCAACCGCATTGCGATCCTGAAGGACGGCGAGCTGGTGCAGGAAGGCACGCCGGAAGACATCCTGCTCAATCCCGCCACCGAATACGTGCAGTCGTTCCTGCAGGACGTCAACCGCACCAAGGTGCTCAACGCGGCGCACGCGGTCAACCCGCCGCGCCTGACCTTGACGATGCGCTCGCGGCCGGCGCATGCGCTGGACCGCATGCAGGCGCTGAGCTACGAGTACGCGCCGGTGCTCGATGGCAAGCGCCTGGCGGGCGTGCTGATGGCCGCCGCCGCGCAGCAGGCGGTGGACGAGGGCGCGCGCGATGTGTCGCGCTTCGTCGAGGACCTGGCCTCGGTGCCGGCCACCGCCGGCCTGGACCAGGTGCTGGCGCAGCTGGTGCACAGCGACCAGCCGGTGGCGGTGACGGGCGAGGGCGACGAGTTCATCGGCATGCTGTCGCGCAAGAAGGTGGTCGAGCTGGTCACGCCGGTGCTGGCCGAGTCCGACTCGGCCGACGGGCAGGGCGATGCCGCGGACGCGGCCTCGGACGGCGCGGGGCAGGCGCACGAGCGCGACGCGGCCTGAGCCGGCCGCCCGCAGGTTTCGCCGCACGCCCCGACGGCGATATGATGGAAGACGGTCACCAGTGGGTGGCCGTTTTCCCAATCGCTATCGGAACCCTGTCATGCCTCTCTTGAATGTACAGATCATGCAAGGCCACCAGCCGGCGCAGAAGTCGGCGCTGCTCGCGGCCGCCTGCCAGGCTGTGGTCGACAGTATCGGCGCGCCGCTGGCCAGCGTGCGCGTCGTGCTGGAGGAAGTCCCTGCCGCCCATGTCATCGTGGCGGGCGAGCTGGGCCGGCAAATGGCGCTGGTGACGGTGGACATGATCGCCGGCCGCACCGACGAGCAGAAAGAGGCGCTGATCGGAGCGCTGAACCGCGCTGTGTGCGACAGCATAGGCATCGACGGCGCGGATGTGCGCGTGATGATCCACGACGTTTCCAAGGCCAACATGGGCGTGGCCAATGGCATCAGCGCTCGGGCGGCGGGCCGCTGAGGCATGCCGCGGCGAGCGGCGGTATGATCGATTGCATGGCCATACCGCATGAAAACAGGAGGAATTGACATCATGAACGAAGTCGTAGTCGTAGCCGCTGCCCGTACCGCCATTGGCGATTTCGGCGGCGGCCTGAAAGATGTGGCGCCCTGCGACCTGGGCGCCACGGTCATCCGGGAAGCGCTGGCGCGCGCCGGCGTGGCCGGCCCCGAGGTAGGCCACGTCGCCGTCGGCCATGTCATCAACACCGAGCCGCGCGACATGTACCTGTCCCGCGTGGCCGCGATCAATGCCGGCATCGGCAAGGAAACCCCGGCGTTCAACGTCAACCGCCTGTGCGGGTCGGGGCTGCAGGCGATCGTGTCGGCCGCCCAGACCATCATGCTGGGCGATACCGAGATCGCCGTGGGCGCGGGCGCCGAAAGCATGAGCCGCGCGCCGTATATCGCCCCGGCGCAGCGCTGGGGCGCGCGCATGGGCGACAGCGCCATGGTCGACATGATGACCGGCGCGCTGTCCGATCCGTTTGGCCGCATGCACATGGGCGTGACGGCCGAGAACGTGGCGGCGCGCTATTCCATCAGCCGCGCCGACCAGGACGCGCTGGCGGTCGAGTCGCATCGCCGCGCCGCGGCCGCCATCGACGCGGGCCGCTTTCGCGACCAGATCGTCCCGGTGACGTTGAAGACGCGCAAGGGCGAGACTGTGTTCGACACCGATGAGCACGTGCGCCGCGACATCACCATCGAAGGCATGGCGGCCCTGCGGCCGGTGTTCCAGAAGGAAAACGGCACGGTCACGGCGGGCAACGCGTCGGGCCTGAACGACGGCGCGGGGGCGGTGGTGCTGATGAGCGCGGCCGCGGCGGCGCAGCGCGGCATTGCGCCGATGGCGCGCCTGGTGGCCTATGCGCATGCCGGCGTGGACCCCGAGATCATGGGCATCGGCCCGGTGCCGGCCACGCAGGCCGCGCTCAAGCGCGCCGGCCTGACCGTCGACCAGCTCGACGTGATCGAGGCCAACGAGGCGTTCGCCGCGCAGGCCTGCGCGGTGACGCGCCAGCTGGAGCTGGATCCCGCCAAGGTCAATCCGAACGGCAGCGGCATCAGCCTGGGCCATCCCATCGGCGCGACCGGGGCCATCATCACGGTCAAGGCCTTGTACGAGCTGCAGCGCGTGGGCGGCCGCTACGCGCTGGTGACGATGTGCATCGACGGCGGGCAGGGCATCGCCGCCATTTTCGAGCGCGTCTGAGGCCCGGCGCTCGTGGCGCCGCTGGCGCCGCGAGCCCGCTTTCGGCATGCGGCGAGGGGGGCGCAGTGGCTACAATGCCGCGATGCCTATTCGCTACACCCCCTCAGAACTCGACCAACCTTCGCTGTCCGAAGCCGACGGCATCCGTTATCTGCATTTCGGCACCGAGTGGGTGCAGGGCGCGATGCTGATCCGCGACCCGGCCCGGCTGGTGCTCGAGTACACCGCCCAGATGATGGCCTGGCTGCTGTTTCTCGAGCCGCCGCGCGAACAATCCATCGGCCTGCTCGGCCTGGGCGCGGGGTCGCTGGCGCGGTTCTGCCTCAAGCACACGCGCAGCCCGGTGACGGTGGTCGAATGGAATCCTCAGGTCACCGCGGTCTGCCAGATGTTTTTCCGCCTGCCCACGCCGCAGCGCCTGGACGTGCATCATGACGATGCCGGCGCCTGGGTGGCCGACCCTGCGCGCGCCGGCGATTGCCCGGTGCTCATGGTCGATCTCTATGACGCGCAGGCGCGCGGCCCGGTGCGCGATTCGGTCAAGTTCTACCGCGATTGCCGCCGTGTGCTGGGCGAGGTGGGCGTGCTGTCGGTCAACCTGTTCGGCCGCCACGAGAGCTACGGGCGCAACATCGACAACCTGAGCAAGGCTTTCGACGACCGCCTGGTGCTGCTGCCCGAGATCGACGCGGGTAACCAGATCGTGCTGGCGTTTTCCGGCCCGCCACTGGCCATCACCCCGGCCGAACTGCTGGCGCGCGCCGAAACCGTCGAGGCGCAGTACGGGTTGCCGGCGCGCCGCTGGGCGCGGGCATTGACCCGCCACGCGGTCGACGGCGTGCTGCACTTCTGAGCGGGCGGCTTCCTCCCCTGGGAATACCCTAGGCGCGCGGTCCTTAACGGCCGCCGCAAAGCAGGCTACCATCGCCTTATTCATAATTATGAATTACGGCCTAGGGGCAACCGATGACTACACCCATCGTCCGGCAGGCGTTGTACCTGGAAGTGGCGGATCGCTTGCGCACCATGATCCGCACCCATGCGCTGGGCGCCGGCACCTGGGTGGACGAGGCGGGGCTGACCGAGCAGCTGGGCATTTCCCGCACGCCGCTGCGCGAGGCCCTCAAGGTGCTGGCTACCGAGGGCCTGGTACGCCTGGAGCCTGGCCGGGGCTGTTTCGTCAACGAGCTGACGGTGCGCGACCTGGAGCAGATCTTTCCGCTCATGGCCATGCTGGAGGGACGCTGCGCCTTCGAGGCGGCGCAGCGCGCCGGCGATGACGACCTGCGCGCGCTCGAACCCTTGCACCGCGCCTTGCAGGCGCATGCGCAGGCCGGCCGCATCGACGCCTATTACGAGACCAACTACTGCATCCACGTCGCGGTGCAGACCCTGGCCGACAACCGCTGGCTGTCCGACATGGTCGACAACCTGCGCAAGGTGCTCAGCCTGTTTCGCCACAAGAGCCTGGCGCTGCCGGGGCGCATCCGCGAATCCTGCGCCGAGCACATGGCCATCTTCGCCGCGCTCAAGGCGCGCGACCCGGAAGGCGCCGAGGCCCTGACCCGCAAGCACCTGCTGCGCCAGTTGGCCGCCCTGCAGGCGCTGGCCGGGCAGGAGCCGGCCGGCGGGGCCGCCGCCATCGATTCACCCGCCGTTCAAGCCGTACAGGAGCTCAACCATGTCCGCACTCGATCCCCAGGCATCCGCACGCGTCGCACGCACGCCTGACGCCGAACCGGAGGCGGTCGACGCATCGGCCGCCGGCGAAAGCGCCGGCCTGATCGCCCGGCTGGGCCGTCTGTTCGAGCGAGACAGGCTGCCGCCGCCGGCCGACCTGGCGCAATTGTTCGAGGCGCGCCTGACCGATGTGCGCGCCAACAAACTGGCGCAGGCCTGGCGCCTGGCCTATGAGCAGGCCGACGGCAAGCGGCGCCGCGCCATGCTGGGCGGGCTGGCGCAGGTCGGCGCCGGCATGCAGGGCGACGGCGCGCAGGGCACGCGCCTGTTCAAACGGTTCAATGCCTTGCCCGACGGACTGCGTTTCCTGGTGGCGCTGCGCGCCGACATGCTGCGCTGGCGCAAGCAGGTCGCCGGACTGCAGGCCCTGGACAAGGAGCTGGAGGCGCTGCTGTCGGCCTGGTTCGACGTGGGCCTGCTGGAGCTGCGCCCGCTGACCTGGGACTCGCCCGCCTCGCTGCTCGAGAAGCTGATCCTCTACGAGGCCGTGCACGAAATCCGCTCGTGGGACGATCTGCGCCATCGGGTGGCGGGCGACCGCCGCTGCTACGCGTATTTCCATCCGCAGATGCCGGACGTGCCGCTGATCTTCGTGGAGGTGGCGTTTTCGGCCCAGATGGCCGACAACGTCCAGGCGCTGCTCGACACCAGCGCGCCGCCGCAGGACCTGGACAAGGCGCGCTGGGCGATCTTCTATTCCATCTCGAATACGCAGCCCGGCCTGCGCGGGATCAGCTTCGGCAACTTCCTGCTCAAGCGCGTGATCGACCGCCTGCTGCAGGAGCTGCCCAAGCTGAAATTCTTCGCCACGCTGTCGCCCATTCCCGGCTTCGCCGACTGGCTGTCGCGGCTGGACGCGCAGGAGGTCGAGCAGGCGGTGCGCGACAAGGCGCGCACGCGCAGCGGCGCTCCGGATGGCGCGCGCTGGGTGGCGCGGCTGGCGCGCGCGGCCACGGGCAAGCCGTCGGAAGTGGTGCAGCGAGCCGGCCTGCGCCTGGCCGCGCGCTACCTGCAGGCGATGCGGGCCGGCCAGCCGCTCGACCCGGTGGCCCGTTTCCACCTGGGCAACGGCGCGCGCATCGAGCGCCTGAACTGGGCTGCCGATACCTCGGCCAAGGGCCTGGCGCAGTCCTGCGGCATGATGGTGAACTACCTCTACGAGCTGGGCGACCTGGATGGCAACCTGGCCCGCCTGAACGAAGGCAAGCCGCAAGTCAGCCGCGGCATCGCGCGCCTGGGATGAGCCGCGCCATGAAGCCGAATTCCCAGCCCGGGCAGATCCTGTGCCGCATCGACGCCGGCGTGGCCCATGTCACGCTGAGCCATCCGGGCCGCATGAATGCCATGACGGTCGCGATGTGGCGGCAGCTGCGCGAGGTCTTCGAGGCCCTCGGGGCGGACGCTGCGCTGCGCTGCGTGGTCGTCGCCGGCGCCGAAGGGCATTTCGCCGCCGGCGCCGACATCCGCGAGTTTCCGGCCGAACGCGCCGACCTGGCCGGGGTGCAGCGCTATCACCGCGAGATCCTGGCGCAGGCGCTGGCCGCGGTGGCCGCCTGCCCGCATCCCGTGCTGGCCCGTATCGAGGGCGTGTGCGTGGGCGGCGGCCTGGAGATCGCCGCGCAGTACGATCTGCGCATCGCCGCCGAGTCGGCCCGCTTCGGCGTGCCGATCGGCAAGCTGGGCTTTCCGATGGCGCCGGACGAAATGCGCGGCCTGCTCGACCTGGTCGGCCGCGCGGCGACGCTGGCCATCCTGCTCGAAGGGCGCGTCTTCGACGCCGCCGAAGCGCTGCGTCTGGGGCTGGTCACGCGCACGGTGCCCGTGGCCGAACTGGACCAGGCGGTGCAGCGCAGCGTGGCCGCCATCCTGGGCGGCGCCCCGCTGGCCGCGCGCATCAACAAGCGCCAGGCGCGCCGCCTGTGCGCCGGCGCGCCGCTGGGCGAAGACGAATACCTGGATTTCTTTTCCTATGCCGAAAGCCGCGACCACCGGGAGAGCGTGCGCGCCTTCCTGGCCGGCACGGCCCCCACATTTACCGGAGACTAGACAAGGTGAGCAACGCCAACCTATATGCTGTGCTGGAGGGGGGCTTCCCCGCCGATCGCGACCGCGTGGCGCTGGAGACCCCGACGCTGCGCTATACCTGGAACGACATCGACCGCGCCAGCGCCTGCCTGGCCAATCTGCTGGCCTCGCTGAAGCTGCCGGCCGGCGCGCGGGTGGCGGTGCAGGTCGAGAAGTCGCCCGAGGCGCTGCTGCTGTACCTGGCCACGCTGCGCGCGGGGCTGGTCTACCTGTCGCTGAACACGGCCTACCGCGAAGCCGAGATCGAATACTTCCTGGGCAACGCCGAGCCGGCCGTGGTCGTGTGCACCAGCGCCAATGCCGGCTGGGTGCGCCGCGCCGCCGCCAAGGCGGGCAGCGCGCACGTCTACACCCTGGACGAAGACCGCACCGGCACGCTGCTGCAGGCCGCCGCGGCGATGCCGCAGCGCTTCAGGACGGTGGCGCGCAAGGCCGACGACCTGGCCGCCATCCTGTACACGTCCGGCACCACCGGCCGCTGCAAGGGCGCCATGCTGTCGCACGGCAACCTGGCCTCCAATGCCCGCGTGCTGCACCAATACTGGGGCTGGCGCGAGGACGACGTGCTGTTGCACATGCTGCCCATTTTCCACGTGCATGGCCTGTTCGTCGCTTCGCACGGGGCGCTGCTGGCCGGCGCGCGCATGATCTGGCTGCCCAGGCTGGACGTGGACCAGGCGCTGCGCTACCTGCCGCAAAGCACCGTCATGATGGGCGTGCCCACCTATTACGTGCGGCTGCTGGCCGACGCGCGCTTCGACCGCGCGGCCTGCGCCAACATGCGGCTGTTCATTTCCGGCTCGGCGCCGCTGCTGACCGAGACGTTCGCCGATTTCCAGGCCCGCACCGGCCAGACCATCCTGGAGCGCTACGGCATGAGCGAAACCGTCATGCTGACCTCCAATCCCTGCCGGCCCGCGGACGGCGAACGCCTGGGCGGCACGGTCGGCAAGGCGCTGCCGGGCGTGCAGGTGCGGGTGGTGGACGACGCGGGCCAGGCCCTGGCGGCCGGCGAGATCGGCAACGTGCAGGTGCGCGGGCCGAACGTCTTCTCCGGCTACTGGCGCATGCCCGAGAAGACGCGCGAGGAGTTCACCGCCGATGGCTGGTTCAAGACCGGCGACGTGGGCCGCTGGGGCGGCGAGTCGGGCGGGCGCGCGGTGCCGGCCGATTACCTGTCGATCGTCGGGCGCAGCAAGGACCTGATCATCTCGGGCGGCTACAACGTCTACCCCAAGGAGATCGAGACGGTCATCGACGAGATGCAGGGCGTGCTGGAGTCAGCCGTCATCGGCGTGCCGCACCCCGATTTCGGCGAGGCCGTGGTGGCGGTGGTGGTGCCGCGCGCCGGCGCGGCGATCGATGTCGCCGCCATGCAGGCCGACCTGAAGTCGCGCATCGCCAATTTCAAGGTGCCCAAGCGGATCCACGTCGTGGACCAGTTGCCGCGCAACACCATGGGCAAGGTGCAGAAGAACGTCCTGCGCGATACCTACGCCGCGTCCTGACGCGATATCGACGGCGCGCGCCGCCAGGGCGCGCGTCCCCATGCAGCAGACCAGAGGAGTGCAGACCACCAGACAGACAACCGCAGGATTTGGACGCGTCAGATGTACATACAAGCCGGCCGCCAGCGTGGCGAGCACGGCGCATAACAGACCGGGCCGGCAGGCCCCGCTACGCTGTACCAACGAGGAGACACCATGAAATACCCCATCCTGGGCGCCGCGCTCATCGCCGCGACGGCGCTCATCGCCGCGACGGCGCTGGGCGCCGCGGCGCCGGCTCAGGCCGCCTGGCCGGAGCGCCCCGTCACCATCATCGTGCCGTTTCCGGCCGGAGGCGGCACCGACACCTTCGCGCGCCCGCTGGCCCAGCAACTGGGCATGCAGCTGGGCCAGAGCGTGGTCATCGACAACAAGGGAGGCGCCGGCGGCACCGTGGGCGCCGCCGTGGCGTCCAAGGCCAAGCCCGACGGCTACACCTTCTTCATGGGGGGCGCCCACCATGCCCTGGCGCCATCGCTGTACAAGAACCTGAGCTACGACATCCAGAAGGATTTCGTGCCGGTGGCCCTGCTGGCGCAGCCGCCCCAGGTCGTGGTCATCAACACCGCCAAGCTGCCGGTCAAGTCGCTGCAGGAGTTCATCGAATACGCGCGCAAGCGGCCGGGCGACATCAACTTCGGCACCGCCGGCAAGGGCAGCACCCACCACCTGGCCGGCGAACTGTTTGCCATGCAGACCGGTATCACGCTGGTCGACGTGCCGTACCAGGGCGCAGGGCCGATGCTCTCGGCCTTGATCGGCGGCCAGGTCGACCTGGCCTTCGACGGGCTGGGGTCGTCGGCGGGGCATATCCGGGCCGGCACCATCAAGCCGCTGGCGGTGGCGGCATCGCAGCGCTCGCCATCCTTCCCCGACGTGCCCACCGCCGCGCAGGCGGGCGTGCCCAACTACGAGGTATCGACCTGGTACGCCCTGTGGGCGCCGGCCGGCACCCCGCAGGAGGCGGTCGACAAGATGACCGCTGCCGTGACCAAGGCCCTGAACGATCCCAAGATCAGGGAAACCTGGGCGGGCAACGGCTCGGCCATCCCCAACCTGACCGGCCCGCAGTTCGGCGCTTTCGTCGACAGCGAAGTGACGCGCTGGGCCAAGGTCGTCAAGGATTCCGGCGTCACGCTGGACTGAGCGGGTGTACAGTGAGGGACGAAAGGGGAGCGGCGCCGGCCGGCGCGGCTCTTCTTTCATCGCTGGTTCCGTATCGCAGGCGGCCTGGCCGCGGGATCGCATGGCGCGGGCTTGCCCGTGCGCGAGCCCCGGCGGGCCCTTTTCAAGGAGCGTGTGATGAAGTCCCTGATAGCCTTGGCTTTGGCGGCCATGTCCGGCGTGGCCGCCGCCCAGTCCGTCGAAATGTCCCTCCTGAGTCCCAAGGGCGACGACCAGAAGATCGGCCAGATCAAGTACGAGCAAACCGACTATGGCGTGCTGTTCACGCCCGACCTGCACGGCCTGGCGCCCGGCGTGCACGGCTTTCACCTGCATGCCAAACCCTCCTGCGCGATGACCAAGGTCGACGGCAAGGACATGGTTGGCGGCGGGGCGGGCGGACACTGGGATCCGGACAACACCGGGGCCCACAAGGGGCCTTATGACAAGACCGGCCACAAGGGCGACCTGCCGGCCGTGTACGTGACCGCCGACGGCAAGGCGACCTATCCGGTGCTGGCCCCGCGCCTGAAGGTGGCCGACCTGGCCGGCCATGCCCTGATGATCCATGTCGGCGGCGACAATTACAGCGATCACCCGGCCGCGCTGGGCGGCGGGGGCGGCCGGATGGCCTGCGGCGTCGTGAAGTAAGGGTTGCGCCGTCCCGCGGCCGGCCGTTCTAGGGATATCCCGCGCCTTGGGGCCGGCCGGCTCACGTTAGACTACACGGTTTCATGGCCGCACGACCTGCGGGAGGCCGCGGGGGCGCCATGGACGATAACTACCCGAGGGTCTAAGGAGCAGACAACATGCTGATCGGAAAAAAACATTTTCTGACGGTAGGCGCGCTGGCGCTGGCGATGGCTATCCACGCCGCACCGGTCATGGCGCAGCAGAAATCGGTGGCGATCACGGCCATCGTCGAACACCCCGCGCTCGATTCCGTGCGCGACGGCGTACAGGACGCCTTGAAGCAGGCGGGTTACGAATCGGGCAAGAATCTGAAGTGGCAATACCAGAGCGCCCAGGGCAACACCGGCACGGCTGCGCAGATTGCGCGCAAGTTCGTCGGCGACCGGCCTGACGTGATCGTGGCGATCGCCACGCCGTCGGCCCAGGCCGTGGTGGCGGCCACCAAGGACGTGCCGGTGGTGTACTCGGCCGTGACCGACCCGGTGGCCGCGCAGCTGGTGCCCTCGATGGAGGCCTCCAACACCAACGTCACGGGCGTGTCCGACCTGTTGGCGCTGGACAAGCAGATCGAGCTGATCAAGAAGGTGGTGCCCAATGCCAAGCGCGTGGGCATGGTCTACAACCCGGGCGAAGCCAACTCGGTCGTGGTCGTCAAGCAGATGCAGGACCTGCTGCCCAAGGCCGGCATGACGCTGGTCGAGGCGGCCGCGCCGCGCACGGTGGACGTGGCCTCGGCCGCGCGCAGCCTGATCGGCAAGGTCGACGTCATCTATACCAACACCGACAACAACGTCGTATCGGCGTACGAATCGCTGGTCAAGGTGGGCAACGACGCCAAGATCCCGCTGGTGGCTTCGGACACCGACAGCGTCAAGCGCGGCGCGATCGCTGCGCTGGGCATCAACTACCGCGACCTGGGCGTGCAGACGGGCAAGATGGTGGTGCGCATCCTCAAGGGCGAAAAGCCCGGCGCCATGTCCTCCGAGACCAGCTCCAAGCTGGAGCTCTACGTGAATCCGGGCGCAGCCGCCAAGCAGGGCGTGACGCTGTCCGACGCGCTGGTCAAGTCCGCGGCGCAAGTCATCAAGTAATCGCGTATTCGGCCGGGCGCCGCGCGGCGCCCGGCCGGCATTTCCACCGAACACAATTCAAGGCAGCGCCGGCCTCATCCACAAGACAGGGCTGGCCAGGTTCTCCTACATGTCATTGTTCTCTTTGCTCGGGGCGTTGGAAATCGGCCTGATCTTCAGCCTGGTCGCGCTGGGGGGGCTGATTTCCTTCCGCCTGTTGCGCTTTCCCGACCTCACCGTCGACGGCAGCTTCCCGCTGGGCGGCGCGGTGGCCGCGACCCTGATCGCCGCGGGCTACGATCCCTTCACCTCCACCATCGTCGCCACCCTCGCCGGCGCCGCCGCCGGGCTGGTCACCGGCTGGCTCAACGTGAGGCTGCGCATCATGGACCTGCTGGCCAGCATCCTGATGATGATCGCGCTGTACTCGGTCAACCTGCGCATCATGGGCAAGCCCAACGTGCCCCTGATCACCGAACCCACCGTCTTCACCCTGCTGCAGCCGCAGTGGCTGAGCGATTACGTGGCGCGGCCGCTGATCCTGCTGGTGGTGGTCATCATCGTCAAGCTGGCGCTGGACTGGTTTCTCGCCACCCAGGCCGGCCTGGCCATGCGCTCGACCGGCTCCAACGGCCGCATGGCGCGCGCCCAGGGCGTCAATACCGGCGCCATGATCCTGGCGGGCATGGCGCTGTCGAACGCCCTGGTGGCGCTGGCGGGCGCGCTGTTCGCGCAGACCCAGGGCGGCGCCGACATCTCGATGGGCATCGGCACCATCGTCATCGGGCTGGCCGCGGTCATCGTGGGCGAGAGCATCCTGCCGTCGCGCCGCCTGGTGATGGCCACCCTGGCGGTCATCCTCGGCGCCATCGTGTACCGCTTCTTCATAGCGCTGGCCCTGAACAGCGATTTCATCGGACTCAAGGCACAGGACCTGAACTTGGTGACGGCCGTGCTGGTCACGATCGCCCTGGTGATCCCGATGCTCAAGCGCCGCCTGGTCGGCAGGAAGGGGGCCTGACATGCTGAGCGCCAAGGATCTGCACATTACCTTCAATGCCGGCACGCCGATCGAGACGCGCGCGCTGCGCGGGCTGTCGCTGGACATTCCGAACGGCCAGTTCGTGACCGTCATCGGCTCCAACGGGGCCGGCAAGTCGACGTTTCTCAATGCCATCTCCGGCGACCTGCCGGTCGACACCGGCACCATACGCATTAACGATGCCGACGTGACCCGCCAGCCGGTCTGGGAGCGCGCCGGACGTGTGGCGCGGGTTTTCCAGGACCCCATGGCGGGCACCTGCGAAGACCTGACCATCGAAGAGAACATGGCGCTGGCCCACATGCGCGGCGCCAGGCGCGGCTTCAGCCGGGCCGTCAAGGCGTCGATGCGCGAGGGTTTCCGCGAGCGGCTGGCGACCCTGGGCCTGGGGCTGGAGAACCGCCTGGCCGACCGCATCGGCCTGCTGTCGGGCGGGCAGCGCCAGGCGGTCAGCCTGCTGATGGCCGCGCTGCAGCCTTCGCGCATCCTGCTGCTGGACGAGCATACGGCCGCGCTGGACCCGCGCACCGCCGATTTCGTGCTGCAGCTGACCGCCCGCATCGTGGCCGAGAGCCAGCTCACCACCATGATGGTCACGCACAGCATGCGCCAGGCGCTCGACGTGGGCGAGCGCACCGTCATGCTGCACCAGGGCCAGGTGGTGCTGGACGTGTCCGGCGACGAGCGCAAGGGCATGGACGTGCCCGACCTGCTGGCCATGTTCGAGCGGGTGCGCGGCGAGAAGCTGTCCGACGACGCGCTGCTGCTGGGCTGAGTCCGCCGGGGCTGCCCCGGGCGCGTCAGTCCAGCACGCCCAGCATCACGCTGGCGGCGTCGAACAGGGCGCAGACCGGCGTGCCGGCGGCCAGCGCCAGGTCGCGCGCGCTTTCCTCGGTGATGATGGCCGCCAGCGTGCCGCCGCCGCCGCGCCCGCCGGCCGAGCGCAGCACCAGGGGTTCGCCGGCCAGGTTGTTCATGGCGTCGATGGCGTCCCAGGCGTCCTTGTAGCTCATCCCGGCGGCGCGCGCGGCGGCGCTGATCGAGCCGGTGGCCTCGATCTGGGCCAGCAGGTCGATGCGATGCTGGCCGCCCCAGGGCTGGTCGCCCGAGCGCAGCCAAAGCGTGCCGTCGAGTTGCAGGGAAGGTGCGGACATGGCGGTCTGGCCGGCGCGGCCGGCGGATGGCGGATGCAAATGAGAGTTTATTGCAAGTTGCCTCCGATCGCGGCATGATGGGCGCTCACACGTCGCTACACAGGTGAGACATGCAGATCGTCAAGTTGCTTACCGTCTCGGTGGCCGCCGGCTTGCTGGCCGGCTGCGCGTCGGGCCCCACGCTACGCAGCGATTATGACCACAGCGCCAACTTCGCGCAGTACCGCACTTTCGCGTTCATGTCGCCGCTGGGCACCGACCGGGCCGGCTACAGCAGCCTGCTGACCGAGCGCCTCAAGCAGGCCACTCGCGGCCAGCTCGAGATGCGCGGCTACACCTATGACGAGAGCAAGCCCGACCTGCTGGTCAACTTCAACGGCAAGCTGCAGGAAAAAAACCAGGTGACGCCGGCGCCGCCGCCCATGGGCCCGTACTACGGCTACCGGGCCGGCTTCTACGGCGGCTGGCCCGGCTACGGCTGGGGCGACGACGTCTACCAGTACACCGAAGGCACGCTGAACATCGACCTGATCGACGCGCGCCGCCGGCAACTGGTCTGGGAGGGCGTGGCCACGGGCGAGGTCAACGATCTCGACAAGGCGCAATCCGCCGCCAGCGTCGAGCAGGGCGTGGCGCAGATCTTCTCCAAGTATCCGTTCCGCGCCGGCAACGGCCAGCCGCAGACGCCTCCCAAGCCGTAGCGGGGCGCCGATGAGCAAGCGCAAGGCGCGCCGCGGCGCCGGCATGCCCGACTACGAGACGGTGGCGCTGGTGCTGCAGGGCGGCGGCGCCCTGGGCGCGTACCAGGCCGGCGTCTACGAGGGTCTGCATGCCGCGGGCATACGGCCGAACTGGCTGGCCGGCATTTCCATCGGCGGCATCAATGCGGCCATCATCGCCGGCGCCCCCGTGGACGAACGGGTCGGGCGCCTGCGCGGCTTCTGGGAAGCCATCTGCCGGCCCACCGGATTCGCCGGGCTGCCCTGGGGCGATGCCTGGGCGGCGCTGTTCGCCAACGCGCCGTTCGGCTTCGGCTCCAACCAGAGCAACGGCCAGCTGGCTGCCTTCAACGCGCTCACGCGCGGCCAGCCGGGGTTTTTCGAGCCGCGCTTTCCGCCGCCGTACCTGGTGCAGGGGGGCGGGGCGGCCGCGACCAGCTTCTACGACACGACGCCGCTGCTGCAGACGCTGCGCGACTATGTCGATTTCGACTTGCTCAACCGCGGCGATGTGCGGGTCAGCCTGGGGGCGGTCAACGTACGCACCGGCAATTTCGCCTACTTCGACAGCCGCGAGACCGTCATCAGGCCCGAGCACGTCATGGCTTCCGGCGCGCTGCCGCCGGGCTTTCCCGCCATCGAGATCGATGGCGAGTTCTACTGGGACGGCGGTCTGGTGTCCAACACCCCGCTGACCAAGGTGCTGGCGGTCCACCCGATGCGCGACACGCTGGCTTTCCAGGTCGACCTGTGGCCGGCGCGCGGCCCCTTGCCCACCAGCCTGGAAGAGGTGGCGGAGCGCCAGAAGGACATCCAGTACTCCAGCCGCACGCGCATCGTCACCGATACGTTCCGCCGCCAGCTCAAGCTGCGCCGCAGCCTGCAGCGCGTGCTCGACCGCCTGCCGCCGCAGGTGCGCAGCAGCCGCGAACTGGCGCAGATCCGGCGCGAGGCGTGTACGCCACTGGTCAACGTGGTCAACCTCATCTACGAGGCCAACCAGTTCGAACGCCATTCCAAGGACTACGAGTTCAATACCGAGTCGATGCGGGAGCACTGGCGCTTCGGCCTGGCCGACATCGAACGCACGCTGGCGCAGCCCGGCGTGCTGGACAAGCCGTCGCCCGACGAGAGTTTCGTGACGCACGACATCCACCGCGCGGACGCTTGAACCTTGCACCTAGGATGAGTCCGCTTTTTTTGGGTTCATCGCGCATTGCCGGGGAAGGCGGCGCGGATTTTGAGGAAGAAGTATTCCTGGTCGCGGTAGCCGTAAGCGCGCCGCTTGATGACCTTGATAGTGTTGTTGATGCCCTCGACAATGCTGGTGTTCAGGGGATGTCGGCATCTGGCCAGGATGCCGTGCAGATAGCCTTTCAAGCGCTGAGCGAAGGTGTTCAAGGCGGGTATTCCGCTTTGCTCGGCCTGCTCGTACCAGTGGTTCCAGGCTTGTCTTGCCCAGGCAGGTCTTTGGTAGAACCAGAGCCGTTTGAGTTCGTCACGCAGGACATAGACCGTCAGCAGCGGCTGGTTGGCTTGCAGCAATTCGTCGAGCCGGACGGCCTGCTGCCGATCCAGGTTGTCACGGTTGCGCAGCAGCAGCCAGCGACTCGATTTGATGATCCTGCGTGCGGGACGATCCTGGCGTAGTTGATTGGCCTGATCCACGCGCACCCGATCAATGACCTCTCGTCCATACTTGGCCACGACATGGAACAAGTCATAGACGATCTCCGCCTGTGGGCTGTGGGCCTGGATCTCCAACTCGTAGGCGGTGGTCATGTCGATGGCAACGGCCTTGATGCGTTGGGCGGCCCCAGGCGGCAATTGTTCGAAGAACGCCCGGGCCGTCTCGCGTGAGCGTCCTGGGCCAATCCACAGCACCTGCCTGCCGATCGGATCGACCACCACTGTCGCGTAGCGATGCCCTTTGTGCAGGGCAAACTCGTCCATCGCCAAATACTCGATCTTGGACCAATCCGGTTCGCGCACCGACGCACGCAGCCGAGCCTTGTCCAGCGTCTTGACGGTATGCCAACCCAGCTCGAAGAACCTCGCCACCGCCTGCACGTTGCTCGATTGCAGCAATTGGCTGCAGGCCTGCGCCAGCCGATCCGTCACCCGTTGATATCGCCCCAGCCAGGCAAGCCGCTCCAGGCGCGGGCCGCCGCATTGCTCACACCACAAGCGTCGGCGCGGCACGTGCAGAACGACCCGATACTCGAATAACGGCAGATCTCGCACCCGTCGAACCGTGGTCTCATGCACCTGGCGACACCGCGCGCCGCACTGCTCGCACAGCATCACCTTGGCCGTTGGCTTCAAATAGATCGACAGCGTGCGCCCTGGGTCTTCGGGCCATTCCACGCGTTCGACGCCATAGCCCTGCCAGCTTCCCAGCGACTCCAGCAACTTGCGATCCAGCATCTCCCTGCACTCCTGATGGCAAATACCTGCCGTCAAGAATACGAAAACTTGCCAAACCCCTCCACGCTATTGCGCGATGAACCAAAAAAATAGCCAACTTTTGAAGTTGGCTATTAGGTAAATACTTGATACTTAACGGAAATTTGGTGGAGCCGGGGGGAATTGAACTGCCGGCAAGCCCAATTTCTTAGGGGGAATATGTCCCAAAAATCAGCCGCTTACGGTGCCGGTTTTGTCGGCCGCCTGGTCTGCGTGTGAAACCGGTGTGAATGCGCCGGCGCGCTGGAAGTTCTTCGGAATGAACTTGCCGTAGATCTTGAACACCATCTCGACATCGGTGTGGCCGAGCTGGTCTGCAATGTACCAGGGATTCGCGCCAGCCGTCAGCCGCGTGCTGGCGTAGGTGTGCCGCATCTGGTATGGATTGCGGTAGCGAACGCCGGCTCGTTTGCATAGGGGCTGCCACAGGGATTTCCGGATCTGCGCATCGGACGCCCACGGCTCGTTCTTCCGTGGGTCGTGCCAGATCCGGCCGCCGGCCAGGAAGGTGAACGCCTTCTGGGCTTTGAGAGCCGCCAGCGCCAGCGGCGATAGATCCACATCGCGTATCCCCGCCTGGGTCTTTGGCGCCTTGCGCACCTGGGCGGCCTTGCCCTCGACCATGCCCGTCACGATGTTGTCGTCGATACGCACGCGACCATGCACCCAGTCCACGCTGGCCCATTCCACGGCCTGAATTTCCCCGGGGCGTAACCCAGCTTCGAACCAGAATTGGATCAGCGGCAGCTCGTCCGCTCGGGCCGCCTGGCGCAGCGCGGAAACCTCGTCCATATCGAACGGATCGACCTCGTAGTTGCTCTTGGTGGCAGTCTGCTTGATCAGCTTGCCAAGGGCGATCCGGTCCAGCGGGTTGCTGTCCAGCAGCTCGTCATTCACGGCATCATCTAGGACCGACCGGAGCGGCGTCAGCCGGTTGCGCACGGTCTTGCCTGTGACGCCCATGCCGGCGATCCAGGCGCGCAGGTCAGCCGGCGCCAGTTCGTTGACGGGCGTGTCGCCCCAGCGCGGGCGCAGATAGTGCTTGATGGCCTTGGCGTACCCCAGCAGCGTGGATGCGGAGATGCTACCGTTGGCGGCCTGCTTCTCGTACAGGGCCAGTTGGGCGTCGAGCAGCGCGCCCAGCAACAGCTTGGCCCCCGGAATTGCGGCCGGGCTCGGCTCCATCCTGGCGGCGGCCGGGGATTCTGGGAAGTAGGTGCGATAGCTGAATGTGCCATCGGTAATCTTGCGGCGGATCTCGGCGCGCAGGCCTGCTGCGTACTCCATATAGGATTTCGTCACCTTGCCCGCGGGCAGCAGTTCGCGGCACTGCTCGCCGCGGTAGCTGAAGGCGATCTGCAGACGCGGGCCGTCCTTCAGCTCCCGAATGGTCACGCCGCGCGGCGGCTTTGGCTCTGATCTTGCTCGACCCATTTGTCGACTTCCTCGAGGTTGATCCAAAGGCAACCGTCAGCCGCCTTCTTATAGTGAACGCCTTCGGTCCAGATCTTCCGGCGATTTTTAGCATAGATGGCATCCGGGGTATCGCCAGACAGCTCGCAGTATTTATTGATCTTGACCCACTTCATGGCCGTTCTGGTGGGCGATACAGGGTCGGGTGCTTGGTGTTGGGCTGCGTGTGCCATCTATTCCTCCCGTTCTTCCTTTTCGATTTCTCGGCTCAGCCAGCGGTGCAGGGCCAGGGCGAGCGCCACGACGGCGCCCACGGCGATGCCCAGCAGGGCGAGGTAGGGCAGGTCAGGCATGGGCGGCCTCCTGCATCTTGGCGCCGATCTCGGCAGCGGCACGGACGATGGCGCGGCGGGTGGCGGCCTCAATCCCGCCGTACTTGTGGGCCGCACATCCAAACCAGGTATCGCCGGGGCGCCGTGCAGAGCCACCATAGTCATCGACATGGACCCACAGGCGCAGCTTCACAGCCAGCCGCAGCGCATCGCCGTCGTCGGTGAGCGGGTTCCATTCGATGCCCGCCACCTTCCCGTGTGGGTCGGCCTTGGCCGGCCGCGTGAACAGCATGTGCGCCTGGAAGCCGGTGCCGGGCCACACTTCGATGCCGGCCGCTTTTGCAGATAAGATTAATAGTTCCAGATCAGTCATAGTGTTGCTCCCGAGTGCATTTCACGCTTCGCCGATACATACGCTAGGCTGGCTTCTTCGGGCGTGCTGAAGGTGCCAATAAATTTCTTTCGGCCATTAACGCGAATCTCCGCTTGATAGCGTCCGTTCGGACGCGCAACCACACCAAGAAAACCAGAACGATTGTTCTTATGAGGGTTCCGCTGATTGTGTGTGTTGTGCTGAGCACTTACGTTTCGCAGATTAGATAGTCTGTTGTCAGTGCGAATCCCGTTAATGTGGTCGATTTGGTTTGGCCACTCTCCATGAACGTAAAACCATGCCAACCTGTGAGCCTTATAAAATCGTCCTGCGATGACAATCTGCTTGTAACCATCGCTATTTATTGAGCGCCCTGCAACGGACCCAGCCACCGAAGCATTGCTGTTTGTCTTCAGCCATCTAAACTCGCCTGACTCCGGGTTGTAAGACAACAGGCTTCGTAGGCTAGCCAGCTCCAACAGTTCGCGGTCAGTTCGCATTGCCGTCCCCCTCCTTGCGCGCGACCAGGGAAAACGAGTTGTCCGCGAACGGCATGGCGCGGAAATCCATGTTCAGGTCGGACTTGCCGCCTATGCCGTGGTGAACGGTGACGGTCGCGCCGACGACTTTTTCAGATAGCGCGACCTTGTTCTGCATGTTGGGAAATTTCAGGCACGGCAGATAGCCAGGGTCGTCAAGGCGGGGGTCTGCGTTGTCGGCCATATCACCTTCGTCTTGCCGCGGCCGGCGGTAGAGGGACGATTTCAAATCCGGACTGAACTCCGACAGCACATCGTTGCTCGTGCGGTAGGTGAACTGCAGAGTGGCGGACGGTTGGTCGTTTTTCTTGGTGTTGGAGTCGAAGTGCATGCGGCACTCTTGTTGGTGGATGCTGAACATGGGGCAGGGCACCAAGTGGTGCTACGTGGGTAATAGGGCGGGCGGCGCCTGGGGATTCCTCCGTTGGTGGCGGCGCCGCCCAGGGAGATCAGGCGGCCAAGCGCTTCAACTGGGCGACCAGCTCGTCGCGCTCGGCCAGAAACTGGAGAACGGCCTTTTCGTGGTCGGCCAGCTCTTTGGCGGTTGGGGTGAAGCGGCAGACGAACAGCTGCAGCTCTTGCGGGAACCGTGGATCGAACGACACGAAGTCGGCGAACTCCGCACCGGTGACCCAGACGTTGTGCAGGCACTGCGGGCGATATTGGTCCGGCAGCGTGCCCGCTTCCAGATAGCGGATGTGCGTGGTGCTTTTCGGGCACTTCGTCTCGAGCACGCCGCGCCGGCCGTCTTCCACGAACAGGCCGTCAACGCTGCATCCGGCCGCCACGTCGGGCAGGTACATGAAGCCGCTTTCGATGGTGACATTGCCGGACGCTTCTTCGTAGGCCATGCGGGCGAACGGCTCCTGATCGATGCCCCACTGCATTTCCTTGCTGGTGTAATCGCTGCCTTGGGGCATGCCCGTCAGTACTTCGATGGCCAGCTCGAACTTGTAGTCGGCGCGCTTGGTCGACCATTCCTTCTTGGCCGTCATCGCCAGCATGTCGGCGGCGCGCGACCCGGTGACGCGGCCGCAGCGGTCCAGCAGCCAGCCGTCGCTGCCCTGCTCATGGGGGGAGAGGATGTAGCGGTTCATTCCTGGATACCTCCTTGGTCATCGCGGCCGAAGCCGTCGTCGGACGGGTCGCGGGGCGGCTCGTCGATGGTCTTGCCGTCATCTGGCGGGGGTTCGATGGATACCGCCTCGCCGCGCAGCACGGCGCCTCGCGCCGCCACCGCGGACTTGAAGGCGTTGTAGATGGCCATGTCCCGCGTGGCGCGCACCTCGGCCAAGCCGTCTTTCCAGACCTTCTCCAGGGCGGCGGCATCCCGGGCCGCATCCACGGCCTTGCGCAGGCGCGGCAGCAGGTCGGGATCGACCGGCGCGCTGGCGGTGGTGGCCAGGCCTTCGCCGCCGTCTGTGTTCAGGTGGTGGATCGCCTCCGACAGGCGGTCGTTCTTCGGCCAGTATTTGTAGGCGCGCTTCACCACCGTCTTTTTGGCCATCTCGCCGTAGTCGGTCTTCCAGGGCGACGACTTTCCGGACTTCACCGACTGGGACCGGTTCATGATCCCGTCGATTTCGTCCCGGCTCATTGGCGTGGTCAGGTAGTCGCCGTCGGCGGTCTTGACCACCACATAGGCCCCGATGATTTCGCCCCGTTCTTTGCTGAAGGGATTGAAGACGTGCGTGGGCGGGGCATCGAAGCCATTCAGGGCGAACGTGTCGGCGGAACGCACCAGCTCGGCCTGGGCCCAGCGGATGGAGCCGGTAGCTACGGCCAGGTCGATTAGGCCCATGTAGCTGATGTCCAGGCAGATCCGGCCGTCGCGCGGCACCAGGTACGCCTGGCGCTTCGCGGGGTTCAGGCTGATGCCAATCGCGGCCACGTTCGTCACCGCGTTGATCACAGACTGGCGGTTGCCCGTCGCGACCTTCAGGGTGTAGTCATTGTTCTGCAGCACCTGGATGGCGAAGCCCGCTTCCTTCTCGAAGCTGATGCTCTGATCGGTCAGCACGGCCGCGAAGGACTCGCGGGCGTTGTAAATGTCCTGGGTGATGACGGCGAGGTTGTTCAAGGGTTATTCCTTCGCGGCGACTGCGGTCTTGCCGCAGCCTTCGCAGGCGGTGAGGGTGGATCGGGCGTCGAGGGTCGGGCCGATCAGGCCGGTGGCTACCGCCAGCGCGGCGACCATGGCGGCGTATCCGGCCAGGTCCAGGTCAAGGCGCGTGGCGCGCAGGTAGGCGATGAGGCGGCGGCTCATTGCCGGCTCCCGAAGGTGACGCGCTGGCCGTCTTCGGTGAGCTCGACCAGCGTGTCCAGCAGTCGGGCGCGGGCCAGCTTGGTCCACTCGACAAACAGCGTGCCGACCGACACCGCGGACTCTCCGCGCGCCGCGGCACGGACCAGCAGCGAGAACGCCGCTTCGGATTGCGCATCGCCGATCGTGGCCGCGTACAGCGCTTCGGCGACCAGCTCCGGATCGCCATAGGGCCAGCGCACGCAGCGCTGCGCCACCAGGGCGTAATGCAGGTCGGCATCGAGGTCGCGCCGCAGCTCGGCCAGCCGCTCGGCGTCGGTCAGCGGGCGCACGACCGCAGCCGTGCCGCACTCGGTGGGGTAGGTGAGGGGAAGCATGGTCAGGCCTCGTCCGACCGTGCAGCCATGTCGCGGTAACGGTCGAAGTCGTCGCGGAACGCCTCTTTCAGGCGCGCGCGCCGCAGCGGGTCGGCCGTCATCCAAAGCCGGGCAAGCTGCTTCATGAACGAACCGCCGAGCTGGGCCATTACCTGCACCGCCTGCTCATCGCTGATGTAAGTGGTTTCCATGGTGTCTCCTGTCCCCGGCACCCGGGGCGGGTGGGGAAGGTCAAGTGGTCTGCTGCCAGGGCGCACGGCCCTCGCACATGGCAATGAACATCTCTTTTTGAGCGTCCCTGGCAGCGCCCAGGGCAGCGGCCCTGGCAGCGGCCCTGGCAGCGTCCCAGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGGCCCTGGCATCGGCACTGGCAGCGGCCCTGGCAGCGTCCCAGGCAGCGTCCCAGGCAGCGTCCCAGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGGCCCTGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGTACCAGGCAGCGTCCCAGGCAGCGTCCCAGGCAGCGGCCCAGGCAGCGTCCCAGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGTCCCAGGCAGCGTCCCAGGCAGCGGCACTGGCATCGGCACTGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGTCCCGCTCTTCCTCGGTGGCTTCGCCGTTGGCGAAACGCTCGGCCACGTCCAGCGCGTCCTTGCTTCGCTGATCCGTCATCAGATGTTCAACTTGGCGAGCGCACCAGACGGCGAACAGGCGCGCATGGCGATCAACACCGGGCACGCAGCGAAGCGCCCACAGCGCGTCATCCAGGCCGTTGCTTGCGATGATGGCCGTCAACGCGACCGGCTCGGCATGTGAAAACTTGATATAGCTTTCGCGCGCGCTGTCATCGTCGGAAAACTCACGGCCCTGAACGGCACGGACGACCTTGTTGTAGCCCTCGAAACATGCACCATCGCGGCGCAGATCAGCGAGCGTGACTTCGAATTTGAGGGTGGCCTTGGTATCGGACACAGTTATCTCCTGGCCCCTACCGGGGCGGGTGGGCAAGGTCAGGCCACGGGCTTGGTCTGCTGCGCGGCCTGTTCGCGCAGGTCGGCCATGGCGAGCTCGTTGCTGGCGAAGAAGTGCGGCGCACGGCCAACGGATGCCATGTAGATCATCCGGCCGGCATACTGCGGCCCGTGCTCACGTTCGAGCGCATAGCCAGCTTCGCCCGCCAGATGGACTGCCCAGCCAGCGCGGCAATGGGTCGTTTCGCAGGTGTGCCATGCCCCCATTTCTAGGCCGCCTCTTCCGTTCTCGATGGCGGAAAGGATCTTCGCGTCCAGCGCTTCAACTACGGGCACGGTGGGATTGAGTTCGCGGAAGCGCGCGGCGCGCGCTGCATTGCGTTCGGCTGCGGGGCGCGTGTCGCGCTGATATGGTTCGACCGGGCTGGTAGCTTCGGTGCCAACCGGCAGGTTTCTCGCGCCGGCCAGGTTCGCGCGGGCCAGGTACGCGCCGGCCAGGTTCGCGCCGGCCAGGTTCGCGCGGGCCAGGTCCGCGCCGGCCAGGTCCGCGCCGGCCAGGTTCGCGCAGGCCAGGTTCGCGCGGGCCAGGTCCGCGTCGGCCAGGTACGCGTCGGCCAGGTACGCGTCGGCCAGGTACGCGCGGGCCAGGTACGCGTCGGCCAGGTTCGCGCCGGCCAGGTTCGCGCGGGCCAGGTTCGCGCGGGCCAGGTTCGCGCCGGCCAGGTCCGCGTCGGCCAGGTACGCGTCGGCCAGGTTCGCGCCGGCCAGGTTCGCGCCGGCCAGGTCCGCGCGGGCCAGGTTCGCGCCGGATTTCACGGCCTGCTCCAGCGCCACACGTGCAACCATGCCGCTCTCGGTTTCATCAGGCACATCAGCCGTGAAGAGCACGGCGCCGGTCCAGCGGTTCTTGATCTCGAAATTCACGTCTATCTCCTGTTGTTGATGCCGGCTGCGCGGGCGATATCTCGGACAACAAGGGATTCAGGGGAGGGCGCGGACGGCGGCGCTTGAGGTTGCGCCCGGCTATCGCCAGCCGTTGGCAGCGCAGCAACACTGGCGGTCAGACTGTGGATCATCCAGTCCGCGAGCCGTTAAGCCGGCGCGCCCTCTCCTGAATCCCAAGTTGTCAAAGAACGTGCCCCGGTACTCCGTGATGCGTGAGTGGTGAGGCGTTGGAATGAACAATAGCAAAACTTTGCTAAAGCAGTCAAGCAAAATTTTGCTAGAGGCATGCTGGCCTAAGGGATGGCGTAAAAAAAGCCCGCGCAGGCGGGCAGCGGGGAACGAAGCAGAGGCGGATGGGTCTAAATTTTGCGGCCCAGAATTTGGGGCCGAAGTCGTGACACTGTTTAACAGTAGCCAAATCGGCTATAGTGTGTACGTGCTCAAATTTGAGCAAGAATTTCCCCTGCCGTGACAGGGTTCGTAGTAGCCGTAGAGGCGGCGTCATCACCTCACCACCGACCTGGATGCACACCTGAAGGGCGGCGCTCGCCCCTACGAAACGTAGGCGAGCAGAAAAGGAGCACCCCATGAAGAACCTACCCCTTGTCTTGCGAGTCTATGGCGAGCGCAGCAATGGCCAATGGTCGCTTATCTGCTTGGATTTCAATCTAGCAGTACAAGCAGACACGCTGCCGCAGGCACAGCAACGCCTCCATTCGATGATTGTCGGCTACTTGCGCGATGCGCTTGAGGGCGAGGATCGTCCGTACGCTGCTCAACTTTTGACCCGTCGTGCTCCGCTAGGGTTTTGGCTGAAGTATTACCTAGCCAAACTACGCACTTGCGTCGCGGGGCAGAGTGGCAGCCGCCGCGTGGCTGGCTCTGAAGCAATCCCAATGGTGCCGGCTGGCGCGTGAGCCGCTGGAAGAGGCCTCTTACTTGCAAAGAGGTGAAGAAGATCCTTGCCAACCTTGGCTTTTCTCATCGGAGCACGGAAGGATCTCACGAGAATTGGATTAAACAGGGCAATTTACGTCGCTGGAAAGTTACGGTTGATTGTCCTAAGGCACCGTTCTCTGACTTCTTGATTAAGTCGATGGCCAGTCAGGCCGGCGTTACGGTCAAGCAGTTTTATGCAGCATTGGATAAGTAATCAGCCGCCCCTAGAGGGCGGCTTTTTGATGGGCGTTGCTCACCTGCGGCAGCGTTGAGCAGATTCTCTGAATGGGAGGCGGGGCAACAAAAAGCCGCCCGGAGGCGGCTACGTGAATCTCGGCTAGGCGGAAAGATCGCTGATGTGAAGCCGGACGATTTCGCCTTCAGCGTCGATTTCTGCCTTGGCCAAGAATGCAACTGGAGAAATCCGCGCCATCGCCACTACATAAGCGTTGTCCGCGCGCTGTACGACCGGGTCTGTGATCACCGCGTTTATCCGTTCATCAGGCGGGAAGCCGTCCAGCGACACCTTGCAATTTCCGGATAGCATGTCTAGCTCAGAAATCACGCCAACGTAGGGGTGCGTCTCGGTTATTGAAGTATCTTTTGGAGCATTCGCAAGCTCTTTAGATGCTCGGTCAAGTACCGTGGCGGGAGCCGGGGTTCCTTGCTGATAGACAGAGATCGTTTGGACTGAACGACCAATAGGGACATGTGCTTGCTTTACCGCAGGTTGCAGCGCTTCGACCATCTTGTCGACAGTTTGGAGCAGGCGCAACTGCATGGCCTCATTCTGGGCCAGAGACTTCTGTAGAGCCTCATTCAGCAGTTTCATTTCTTCGCTCTTGCGCCTATTTAGAACAACCGCTACGACTGCAGTAAATCCCAATGGAAAGCGAATCGGCATCAGAAACGCTCTTCGCGATAGACCGAGCGCCATTCTCGCTGGCTTGAACCCAACGCTCGAGCGCCGGGACTTCTTGAGCCGCCTTTCTGACAACCTCCATCTGTGCTGTCTTCTCTTGCTCCACGCGAACAGACTTATCCGCAGCGATCTCGTTATTCTTGATCCACGTCAAGCCAGTACCCGCCGTCAATGCTACGACGGTCGTTACCAAGAAGATCAATTTATGCCTGCTTTCCATGGAGTTCACGGCATCCTTGAGATGGCCAACGATGTCCTTCAGATCGGCGACGAGTTTGGAGCAACCGTCCTCTACGTCAATGACTAGATTGTAGTCGTGCAGTTCTTCCTTTGTAAGCCGCTTTATGTTAGGCGCGCCATGAAGCGTAGCGGCTACTGCACGGTAAATCTCCTGCTGCAATTCCCAGAGGCCTCTGGATAAATTTCCAGTCACCGACGAGTGATAGTTCGTGCCCTCAATCTCAATGAGCATTGAGGCCAGCTCACCTTTGATGTCAATATCTTCAGGGAGGCTGTCTTCCGAAGAGTCCGGATCGAGCAAGGTTTGCAAAAACTGCAGCGCTTCTTCATGAGTGCTTAAGACTACGACTTCGCCGGCCAACCTGATCTCCTTATGTGCTTGTATTGCACTCAATTTCTTTCGACGCTCGGGCGTCTTTTAATGTCTAGGCTTGCAAGCTCAATTGCTTAAAGCTGCACCCACCGCCCCGCCTCACTATCCCTCACGCCAGCCGCACTCCCGCCCACACCACGCGCCCAAGCACCCGCACGGGCGCGCCGTTCTCCAGCGGGACATCCTGGTAGCGGTCGTTGAACGACCGGGCCACCCAGCGGCCGGTCAGGCGATCCTTGGCCACGGCCTTCACGATCATCTTGCCGTCGTAGTTGATGGCGTAGATCCCGCCAGCGGCCAGGTCGCGCAGCGTCAGGCCCTCATCCGGTACGACCAGCAGGGCGGCGCCGTCGCGGATGACGGGCTCCATACTGTCGCCTTTCGCATACACAACCCGGGCCCGGCCACCATCGGCGCCCACCGAGCGCAGGAACGAGCGGCGGAACTGGATCATGCCGGTTTGGTCCTCGGCGTGGTTCTCGATCCCGTCGCCCGCAGATAGCCGCACATCGGCCAGCTCCGGCACCTTCTCGAACTTGTCGTTGGCCGCGGGAGGATCGCCAGGGGCGACGTTCGCAACCACGGACTCGGCAAGGCTCAGCTTCAGGGAGCCTTCACGTTCCATCTGCCGAGTCGTCTTGCCGCCTGGCTCCCATGGCGCGGGGACGCCGCCGATACGCATCGGAAACTCATCCGCCGCGGCTTCGATGTCGACCAGGCCGCCGGAGCGCGGAGCAGGGGAAGGCTTCGCCAGTTGGCTCGCGGCAGGTTCACCGCCTTCCGGGTGCAACAGATCCCATGGCGCTACGCCCAGCGCACCGGCTAAGGCTTCAACCTCACCGAATTTAGCCGACGGCACCTTGCCGCTCTTGCTAGGCTGCCTCCGCGCGGGATTGAGGTAAAGACTAATTGTGGTTTGCCCCACGCCCGACAATTTGGCGAGCGAAGCCTGCTTATGGCCGGTCTTCTCCATAAGCCTTGCTAGATTGGCTGCCAGGACGTCGTTTAGGGTGGGGCGATTCATGTCGCGAGTGTGCAATGCCTTGCTAGCAAAGTGTTGCTTGCTTCCATAGCAAAGTTTTGCTAATGTGCGGTTATGCATATGCCCCTCGACCAATCCGTTCGAAATTCGCTCCTTGCCAGACGCGGCGAGTGGGCCGATATCGCCAATAGTTCACAGGTATCCCATTCGTGGATGTCCAAGTTCGTAAATGGCCATATCCCGAATCCTGGCTACGCGACCCTTTCGCGCTTGGCCGCTTCTCTTGGCTTGCTGAGCGATGACCTGGCTGCGGTGGAGCGAATCTCGACGGAGGGCGGGCCTCAGGAGGCGGGCCATGCGTGACCTATATGCCCGCCTCGTGCTGGCGTTGATACGTCCGGCGCTCAAGCTGCAACAGCGGAGAGACGGGCCCCGGGTGGCAGCGGTGCTGAAGGAAGAGCTGCGCTGCAACCCTGGGGCGCACCTGTTTACCGCGTCTGAGCTCGAATCTGGGCGGCGAGGTCTTGAAGCGCACATTCTGTCGCGCGTTGACGCTGTTCGATCTCGCCAATCTGCTTCGCGAGGGCAAACAGCCCGCAATTCAAATTCCACGCAAGCGCATTTGCCGAGCGGCAGGAGGCAGCTTGACATGACTTCCCACCCCACAGCTAAGGAGGCCTCGATGGTCAACCCGATTGAACCTGGCGTTATTCCGCACGAATTCCAGCGCGACGTGATCGCCGCGGCGATCAAGTCGGCAGCGTTCGCCTTGCGCCAGAGCCGCGAAGCCGATCCGGCGAAGGCCGCCCGCCAGGTGGCGGAAGCGGCCGTTGTTGCGTGGGAGGTCGTGAACGGCCTCAGTCGTTCGGCGTCACCTTCTCCTCGTACTGCCGGTTGAACTCGTCGATGAACGCCCAGGCCATTTCTGCGAGCCTCTTCCCGGCGAGAGCCCCGTGGCCGCTCGACTGGATCAAGGCTGGTTGCGCCTTGGCAATCTCGACAAAGAGGTTGGCGCAGTGATGGTACTGCGAACGGTCCATGAGAACCCCTCCTGTGGGGAAAGTTGGTTGTGGTTGGTCGCCACGCCCGGGCAATTCGGGCAATGCCGATCGTAGCCGCGGACAGGGGTTCTCGCCAGTTTCGGGCCGCCATGGCTCAGTGCACCGTCGCGCCGGCGGCGTCAGAGCCTTCCCAGGCCCGGCGGTCTCGCTCTGCGCGCAGCTCGTCGAAAAGGTCCATGACCGTCTTTTCCGACGGGTCATCGAAGGCACGCCTGGCGATTTCCTGGGCGTGGTTCAGCAGTTTTTCGGTTTCCGTCTGGATTGGGACAAGGCAAATTCTCCATATCCCGACTCTGTTACCGACGCTGTTACTCCATGAAATTTCCCTATTAGGCGTATTCGAAAATGCAGCGAGAACAAGGGGTTGGCCTCGATTTCCTGCGCATCCGCCCGTCTGAACCAATGCTGTTCATAGACAAGGCGGAAATCGCGCGATGCGTGACCTACCGCCAGGCGGTGAGACTTGCCTGGGACATGCGCCAGCCGCGCGGCATGACGATGCGAACGCTTGCCGAGTTATGCGGCATGTACCCGCAGCACGTCAGCAGCTACCTCCATGAGGATCCGCTACTGCCGAGCAGTTTTGCCAAGCCGTCGCCCAGCGCTTTTTCGATCGAACTGATGGGGTGGTCCTTGAGGACGTTGTCAGACATTCGGGACTCCTTAGTTGGATGGGCGCTTAGTTTCGCACAGCGATGCGGCAGGGATGTGCGCTCATGAGCTACGAGGTCATGAAAGCCTGCCGGCCACTGCAAATGCCTTCCTCGCCGAAGGCCGTGCTGATGGCGCTGGCCGACTATGCAGACGAGGCTGGATCTGCGTGGCCATCGATTCCCACGCTGTGCGAATACACGTGCCTGTCCGAGCGCACTGTTCACGCCGCCATCAAGTGGCTGGAACAGGCCAAGGTGGTGGTGGCCGACCGTGCCAACGGGCGCCACACAACCTACGTTGTCGATGCGAATTCCTTTCAACAACCCCCGCAGCAGTTGCGCCCCCGCAGTAGCTGCACCCCCGCAAATCCCGCAGTCACCCCCGCAGTAGCTGCGGTGGTACCCCCGCAAATCCCGCAGTCACCCCCGCAGCAGCTGCGGTCTAACAACCAAGAACAACCAAGGGAACAACCAGGAACAACCAATAAGCGCGTGCGCAAGCCGAAGGACTCGGGCTTCGACGCGATGAAGGTCGACCTGCCGGACTGGCTGCCAGCGGAAAGCTGGGAGCGCTGGGTCCGCCACCGCGTGCAGCTGAAAAAGCCGATCACCGAGGAAACCGCGCGCCAGCAGATCGAAGACCTGGGGACCTTCCGCGGTCAGGGCCATCAGCCGGACGACGTCATTCGGCACTGCATCGGCAAGAGCTGGCAGGGACTGTTCCCCCCGAAACAAGGCTTCGGGCCACGCCCGGCGCCTGCCGTGAGCGAGGCAGATCGCCGCAAGCAGGAATTCCTGCGCCTGGCGGGCCACGGCGGCAACGACAGCGGCACCATCGACATGGAGCAAGCCTGATGCACAGCCGCGACGTTTCCGCCTTCGCCGAGCTGCTGGCCGGCGTCTTCGATGCCTACAACCGGCTGCCGCCGCAGCCGGCCACGCAGTTGCTCTGGCTGCGCATGCTCGAGCCTTACGAGTTCCCAGCGGTGAGCGCCGCGTTCTCGCAGTACGTGGCCAACGAGGTCAAGTTCCCGCCGACGCCGGCGCAGATCCTGGCGCTGCTTGGTCACGGCACCGGCGACAGCCGGCCCACCGCTGACGAAGCATGGGCCACCGCGCTGGTGTCGCGCGACGAGGCGGAAACGGTGGTCTGGACACTGGAGACGGCGCAAGCCTTCGCGGCGTGCCGCACCGTGCTGGACCTGGGCGACGAGGTGGGCGCGCGCATGGCGTTCAAGGGCGCCTACGACCGGCTGGTGGCGCGGGCTCGCCATGATCGCCAGCCGGTGGCCTGGCAGGTATCCCTCGGTTGGGACCCCGACCGCCGCGAGCGTGCGCTGACCGCCGCCGGAACGGCCGGCCTGTTGCCGGCGCCGCACGTCGCCGCGCTGCTGCCGCCGCCTGATCCTTCGGGTGGTCTGGGCGATGACGCCGTCGCCGCCGAGAACATCGCGCGCCTGCGCAAGCTACTGGCCGGCGCGCTGTCCCCATCCGAGAAACGCCGCCGCGCCGCAGAGCAGGCCGGCCAGGCCGAGCGTGACCGCCTCGACGTCCTGAAGGCCGAGACGGCGGCCAAGGTCGCCCAGCACCAGCAAGGGGTCCGCGCATGAGCAGCTACGCCGAAGCCAGCGCCGCCGTGGGCGGCAACGAAAGCGGGGGCTATGGCGTCTGCGCTGCCTACGGCTGCTGCCTGCCGGGCACGATGACCGACAGCACTCGGGGCGGCAAGGATTGGCACTGCCGCCTGCACTTCGGCGCGCCGCGGTCCGAGTTCGACGATATCAGCGCGCGGGTCCAGAACCGCAAGGCCCTGTTCCTGGCTGCCTACTGGCTGGTCAACCGTTCCAAGGGTGACACCGTCAGCCGCAAGGTGCGGGATCGCATCAAGGCCCTGGGCCGCGCCGACCTGCTGGAGAAGGTGCCCAGCGTGCGCGGCGTCACCGCCTACCACCTGGGCGTGCACATGCTCCGCGTGCTGGGCGACGAGTGCCGCCAGCCCCAGGAACACATGGGCACCCCGAAACGCGCCGGCCAGGGCACCACCTGGCTGGACCAGACCCAACCCGAGGAAACCGACGCATGAACGCCTCACCCAACCTCACCGACCCCTACGACCCGCTGGCCGGCACGCTGGCCAGGACGGCGATGCAGTGCCAGGCGCGCGGCTGCGACGGCTGCATGGTGTGCGTCCCGGACAGCTTCGCGCGCGCGCAGGGCGAAATTGCCAATTTGCGCAATTCGTCAAGTTCGGCCCCCGGCGAGGCACCCGCGCTGAACGTCAACATCCTGGCGCTGGACCTGGGCACGAAGACCGGCTACGCGCTGCGCCGGCGCGACGGCCGCATGGTGCACGGCACCGAGGAATTCACGCCGCGCGCGAGCTGGGCGCCAGGCCAGAAATGGCTGCGCTTTCGGTCTTGGCTGTCGGCGACCATCACCGAACACAGCATTACGCAGATCGCTTTCGAGGACGTCAAGCGCCATGGCCCGGGCCAGGTACTGGCCGCGCATGCCTATGGCGGCTTCCGCGCCATGCTCGAGATGGTGGCCGACCAGCACCGCGTGGCCCTGGTTCCTTTCGGCGTGGGGCAGATCAAGAAGCATTGGACCGGCTCCGGCGTGGCCAAGAAGGACGACATGCTCATGCAGGCCAAGGTGCGCGGGTTTGCCGCTGTGGACGACAACAACGCCGACGCGCTGGCGATCCTGCATCTGGCCATCGCCAAGGAAAAGCGGGAGTGGGCCGCACCGCCGGCCAAGTCCAAGACGCGGCGCACGCGAAAGGCCGGCGCCGTGGCGCACGAGCGCACAGCATGACCTGGGCCCGCCGATCCGATCGAGGTGATCCGGCCAAGGTGCTGGAGCGCCGCCAGGAGCCGCCGCCTGTGCGCAGTTGCGCTGGCTGCGCATGCTCGAGCCTTACGAGTTCCCAGCGGTGAGCGGCGAAACCGTGGAGGACTTGGTGTGAAGAACCGCCAGCCTGTTCAAACGACGCTGCCGCCCGAGGCCATGCGCCTGCTGCAACAGGCGGCACAAACGCCCATCACGCGAGCCGACCCGCTCGCGCGTGTGAAAGCCATCGAGAAAGCCACCGAGCGGGTCAAGCGTCAATACCCCCAATTTTTCAAGGAGTGAACACCATGATTTCTCTGTTGCAACGAGGTTAAGGGTGATTGCAATGGAGTATATGGGACGTTAAGGACGATTGCGACGAGTTTTTTTATAACTCCCCATGTACACGTATAGGGAGTTTTATAAATTTCCATTGCAATCGTCCTTAACGTCCCACGCAAGAAATTGCAGATTCAAAGGAGGGCGGCGCATGCAGAAAACGGTGGCGGTGAATGAACGAGGTTTGCGGATTGGTCAGGATCATCAAAACGCCCGATACACGAACGGGGAAATCGAAATGGTTTTGACCCTGCGCGACGACGGCAAAAGCTATGGCGAGATTGCGCGCCTGGTGGAAATGCCGAAGAGCACGGTGCGCGACATTTGCACCGGGCGTCGTCGGTGCCAGTACGCGGCCAACTTCAAAACCGTGCGCGTACCGGATGGGCAGTAGGCTGGAATGGGCAGCATGAAATTGACACCTGAAAAGCTCACCGCGTTTTGCGCAGCCCTGGCCGAGACTTGCAACGTCGGCCGGGCGTGCGCTGCCGTGGGCATTTCGCGCCAAACCGCCTACAACTGGCGAGAAGCCGACGCCGACTTCGCCTTGGCCTGGGAACGTGCCATGAAGGCCGGCCTGCTGGCCCTTGAGGATGAAGCGCACCGCCGTGCGTTCGAGGGCACCGACGAGCCGGTTTTCTACAAGGGCGACGAGTGCGGCAGCGTGCGCAAGTACAGCGACACCCTTGCCATCTTCCTGCTCAAGGCCCACGCCCCAGACAAGTACCGGGAAAACACCCGCATGGAACTGACCGGCGCCAACGGCGGCCCGGTGCAGATCAACGATACCGAGCGCGCCGCGCGCATCGCGGCCATTGTTGCCGCCGCCCAGCAGCGCGCCCAGCGTGCTGCCGCTGGTGAGGACGACGACCCCGCCGCGGGGCTGGTATGAGCAGCGTTGCCGAAATCCGCCGGCTGATGGCGTACATGACGCCGGCAGAACTCGCCGAGGTGGACGCGCTGCTGGCGACCGCGCCGCCGTGGTTGCCACTGCCTGGGCCGCAGACCGCGGCGTACAACTCCGACGCCGACATTATCGGCTACGGGGGCGCCGCCGGCGGCGGCAAAACCGACCTCATCGCGGGCCTGACCCTGACCAAGCACGAGCGCGCCCTCATCGTGCGGCGCGAGAAAGCGCAGACCGAGGGCTTCGTGCAGCGCATGACGGAAATCATGGGCGGCACGGATGGTTACAATTCGCAAAAGGGATTCTGGCGCCTGCCCGGCGGCCGGCTATGCGAACTGGCCGGCCTGGACAACCCCGGCGACGAGCGCCGGTGGCAAGGCCGGCCGCACGACCTCAAGGCATTCGATGAAGTGACCGAGCAGCGCGAGCAGCAGGTGCGCTTCGTCATGGGCTGGAATCGCACAAACAAACCGGGCCAGCGGTCGCGCGTGCTCATGACCTTCAACCCGCCGACCACCAGCGAGGGCCGGTGGGTTATCGACTTCTTCGCGCCGTGGCTGGACAAGAAGCACCCGCTGTACCCCACGGCGCCGGGCGCGCTGCGCTGGGTGGCGATGCTGCCCGATGGTAACGGCGGATCGCGCGACACGTGGTTCGACTCGGACGGCAACCCGCTGTCGTCGGCCCCCTTCGTGCTGGTGGGCGGGCGCGTCGAGTACGACTTCGACCCTGCGGACTACAACCCCGAGGACATCATCCAGCCCAAGTCGCGCACGTTCATCCCGGCGCGTGTGACCGATAACCCGTACTACGTCGATAGCGGGTATCTCGTCACCTTGCAATCGTTGCCCGAACCATTGCGCAGCCAGATGCTTTACGGCGACTTCAACGCGGGCATCGAGGACGACCCGTGGCAGGTCATCCCGACAGCATGGGTCGAGGCCGCGCAGGCGCGGTGGAAGCGGCCCGACCGACTGGCACCGATGGACAGCCTGGGCGTGGACGTGGCCCGCGGCGGGCGCGACAACACCATCCTGGCCCGCCGGCACGCCATGTGGTTCGACGTGCCGCTGACCTACCCCGGCAAGGACACGCCGGACGGCCCGACCGTGGCCGGGCTGGCCATCGCTGCGCTGCGCGACCACGCGGTCATCCACCTGGACGTGATCGGCGTGGGCGCCAGCCCCTACGACTTCCTCAACGAGGCCGGGCAGCAGGTCGTCGGCGTCAATGTCGCCGAGTCCGCCGTGGGCACCGACAAGTCGGGCCGCCTGCGCTTCAAGAACCTGCGCAGCGAGCTATGGTGGCGGATGCGTGAAGCCCTGGACCCGACCAACAACACGGGCATCGCGCTGCCGCCTGACTCGCGGCTGCTCGCCGACCTCACCGCCCCCACGTGGTCGCTGTCTGGTGCCACGCTCAAGGTGGCGAGCCGCGAGGACATCATCGAGAAGATCGGCCGCTCGCCGGACTTTGGCAGCGCCTACGTCCTCGCGCTCATGGACACGCCGAAGCGCTCGGTCGTCGAAGCCATGGGCCAGCGGCGCCGCCGGGATTACGATCCTTACGCTACTTGACGCAGTTGTAGGCCAGTTCGAAGTCGGTCACTTTGCCGGCGAACTGTGCGTGCCGGCCGTACTTCGCACAATGCGCCTGGGCAGCTTCCAGGGCGCCCGTGGCGCCGCGCGTCGAATGCGCCCAATTCACGGACACTGCGTTCTCGGTGCCCTTGATGATGAACGGCGGGCGCGCTCCCGTTGTGGCGCAACCCGCAGCCAGCGCGGCAAATGCAGCAATCCTCCCTGCCGGTTATCCGTTGCAAATTGCATTTTACCGGGTGCGCGTACCTGATAACAGGCCCCCTAGTCTTGCGCGCATGGAACCGACCATTCGCACCATCACCGTAGACGAAGCCTTCGACTCGCCTGTGTTCGCCGCCCTGTGCGACGAGTACCGGGCCGAATCGCTGCGCAACCCCGACATGATGGGGGCGCTACCAGACCGCGAAGGCTACGCCCGCATGGTCGACGCCGGCCTACTGCACCCCCTGGGCGTGTTCGTCGGCGAGGAACTGGTCGGCATGTGCGCCGTGCTGATTGCGCCCGTGCTGCACTTCGGCGGCAAGGTAGTCGCCTCGACTGAAACCCTGTTCGTGGCCGAGGCACACCGCGCTGGTGGCGCCGGCTTGAAGCTGCTGCACGCCGCCGAGGAAGTGGCGGCCGAGGCAGGGGCCGGCGGCCTGTACGTGACTGCCCCAGCCGGCGGGCGCCTTGAGCGATTGCTGCCGCGCGTGGGCTACCACGAAACCAACCGCATTTTCTTCCGGGGGCTGCTGTGAGCGGCCTTGTGGCGGCAGAAAGCCGCATTCCCGCCATGACGGCCCAGGCTATCGACAAGGTGCGCGAACTGGAAGCCATCACGCGCGACCTGCCGCAAGTCGAGATTGCCACCGACCACGTGCTGCATGGCGGCATGTACGCGCGAACGATCTGCATTCCGGCCGGTGTGGTGCTCACGGGGGTGTTCATCCGCGTGCCCACGCTGCTGGTATTCGACGGCAACGCCACGGTCAATGCCGGCGACGACGCCACCACGCTGGTGGGCTACCACGTGCTCGCCGCCAGTGCGCACCGCCGCCAGGCATTCCTCGCCCATGCCGACACGCGCTTGACCATGGTGTTCGCCACCCAGGCCAAGACCGTGGCCGAGGCCGAGGACGAATTTACCGACGAGGCGCACTTGCTGTTCTCACGCAAGCCGGGCGCCGTGAATCGCATCAACATCACAGGAGAGTAATCATGTCGGGTGCAGCTACCGGAGTCATGGCCGTGGCCGCAGTTGCTGCCACTGCAATCGCCTACAACAACGGGCAGCAGCAGAAGAAGGCCGCCAAAAAGGCAAGACAGCAGGCCGAGGCCAACGCCAAGAAGCAGGAGAAGGCCGCCGACGAGGCGACCAACCGAGCGAACACCAAGCGGGCCGATACCGGCGCCGCGCTCGACTGGGCGACCCAGGCGGGCAAGGCCGGCGCATCCGGCACCATGCTGACCGGCCCGCAGGGCGTTGACCAATCGGCCCTCACCCTGGGCAAGTCCACTCTGCTGGGGCAATAACGTGGCCGAGCAAACCGAGCGCAAACTGCTGCTTTCGCGCTGGGGGCAACTGCGCACCGAGCGCGAAAGCTGGATGTCGCACTGGAAGGAAATCAGCGACTACCTGCTGCCGCGCGCGGGGCGCTTCTTCGTCGATGACCGCAACCGGGGCGACAAGCGGCATAACAACATTTACGACAGCACGGGCACCCGCGCGCTGCGCGTGCTCGCCGCCGGCATGATGGCCGGCATGACCAGCCCGGCGCGGCCCTGGTTCCGCCTTACCACGTCCGACCCGCAGTTGGATGAGTCGGCGGCCGTCAAGGCGTGGCTGGCCGACGTTACCCGCCTCATGCAAATGGTGTTTGCCAAGTCCAACACCTACCGCGCCCTGCACTCGATGTATGAGGAATTGGGCGCCTTCGGCACGGCGGGCGCCATCGTGCTGGCGGACTTCAATTCGGTCATCCACCACTACACGCTGACCACGGGCGAGTTCGCCATGGCCGCCGACCATCGCGGCCAGATCAACACGCTTTACCGCGAATTCCAAATGACCGTGGCGCAAATGGTGCGCGAGTTCGGCCGCGACAATTGCAGCCCGACCGTGCAAACCCTTTTCGACCGTGGCGCCCTGGAACAGTGGGTCACGATCATGCACGCCATCGAGCCGCGTGTCGACCGCGACGTGACCAAGCGCGACGACCGCAACATGGCGTGGAAGTCGGTCTATTTCGAGCACGGCGGCAACGAGGACCAGATCCTGCGGGACTCGGGCTTCAAGGAATTCCCGGCCTTGTGCCCGCGCTGGGCTACGTCCGGCGGCGACATTTACGGCAACTCGCCGGCCATGGAAGCGCTGGGCGACATCAAGCAATTGCAGCACGAGCAACTGCGCAAGGCCCAGGGCATCGACTACAAGACCAAGCCCCCGCTGCAGGCGCCCACGTCCTTGAAGTCGCGCGACGTGGATACCTTGCCCGGCGGCATTTCCTTCGTGGATTCGGCCGCCCCCAACGGCGGCATCCGCTCGGCCTTCGAGGTCAATATCGACCTGTCACACCTGCTGGCCGACATCCAGGACGTGCGCGAGCGCATCAAGGGCAGCTTTTACGCTGACCTGTTCCTCATGTTTGCCAACGGCACCAACCCGCAAATGACCGCCACCGAGGTGGCCGAGCGCCACGAGGAAAAGCTGCTCATGCTGGGGCCGGTGCTCGAACGGATGCACAACGAAATCCTCGACCCGCTCATCGAAATGACCTTTTCGCGCATGGTCGAGGCCAACATCGTGCCGCCCCCGCCGGACGAATTGCAGGGCATGGAACTGAACGTCGAGTTCGTCAGCATGCTGGCCCAGGCGCAGCGCGCGATTGCCACCAACTCGGTGGATCGCTTCGTCGGCAACCTGGGCGCGGTGGCCGGCATCAAGCCGGAAGTCCTCGACAAGTTCGACGCCGACCGCTGGGCCGACGCCTACGCCGACATGCTGGGCATCGACCCCGAGTTGATCGTGCCGGGCGAACAGGTGGCCTTGATCCGCAAGCAGCGCGCCGAAGCAGCCCAGGCCCAGCAGCAGGCCGCGCTGCTCAACCAGGGCGCCGACACCGCGCAAAAGCTAGGCAGCGTGGATACCAGCAAGCAAAGCGCGCTCACCGACGTGACCCGCGCGTTCAGCGGTTACACCTGATAGGGGTGCGCGTACTGCGACGCATGCCCAATAGATTGCGACCATGAGCAATTACGACCCGACCGACATTCGAAGCCAAGAGCGTGCAAAGGCCGACACCGACCTGCGCAACAGACTGGCGAAGGACACGGAAGAGTCGGACCTGAAATGGCTCATGGGCAGCAAGCGGGGGCGTTGCATCGTGTGGCGCTTTCTGGACCGAGCCGGGGTTTTCCGGCTTTCGTTCAATACCAACTCGATGACGATGGCGTTCAACGAGGGGAACAGGAACGAGGGCCTGCGCATCCTGGCGCAAATTCACACGCTCTGCCCGGAGCTTTATCCCGTAATGGTGAAGGAACAGATCCATGACAACCGAAACGCTGATGACGGAAGCCGCAACGACCACTGAAGGCCAGCCCGCATCGCAACCGGCCGCCGAACAGTCCGCTACTGGTGCGGGCAACGACGGCCAACAGCAGCAACAGCCGACCCAGGAGCAAGGCACCCAAGGCCAGCAGCCGGCCGCGGGCGCTGCCAAGACCGAGGGCGACGACAAGGCGAAGCCGCAAGGCGCACCCGAGCAATACGAATTCCAGGCCCCCGAAGGCGTGGCATTCGACGACGGTGTGCTGGGCGCCTTTTCCGAAGTCGCCAAGGAACTGGACATGCCCCAGGACAAGGCGCAACTGGTGCTCGACAAGATGCTGCCTGTGATGCAGGCGCGCCATGCCGAGCAAGTCGGCGAGTTCTACGCGGACATTGGCGGCCTGCCCGAAACCTGGGTTGCCTCGTCCACGGCCGACAAGGAGTTCGGCGGCGACAAGCTGCAAGAAAACCTTGCCACGGCCAAGAAGGCGCGCGACGCCTTCGGCACGCCCGAACTCACCACGCTGCTGAACAAAACCGGCCTGGGCAATCACCCCGAAATCATCCGGGTGTTCTACCGGGCCGGCCTGGCAATCAGTGAAGACCGCCTCGTGGCCGGCAACAACGGCAACCAGCCCAAGCAGGGCGATGCGCGGCGCCTCTATGCAGCTTCCAACATGAACCCGTAAAGGAGCGTTCCAAATGCCTACTCTTTCCACCACCAACCCGACGCTGGCCGATGTCGCGGCCCGCATGACCCCGGACGGCAAGATCGACCCGCAGATCGTCGAAATGCTGAACGAAACCAACGAAATCCTCGACGACATGACCGTCATCGAGGCCAACGGTTTCACCGAGCACAAGACCACGGTTCGCAGCGGCCTGCCCACCGGCACCTGGCGCAAGCTGAACTATGGCGTGCAGCCCGAGAAGTCCCGCACCGTGCAGGTCAAGGACAGCATGGGGATGCTGGAAACCTACGCCGAAGTGGACAAGGCCCTGGCCGACCTCAACGGCAATTCCGCCGCCTGGCGCCTGTCCGAAGACCGCGCCTTCATCGAAGGCATGAACCAGACCCAGGCGACCACGCTGTTCTACGGCGATTCCAGCATCGACGCCGAGAAGTTCATGGGCCTGACGCCGCGCTTCAACAGCCTGTCCGCGGAGAACGGCCAGAACATCATCGACGCCGGCGGCACGGGCAGCGACAACGCATCCATCTGGCTGACGGTGTGGGGGCCGAACACCCTGCATACCATCTACCCGAAGGGTTCGCAGGCCGGCCTGCAATCGAGTGACCTCGGCGAGGACACGCTGATCGACGCCGCCGGCGGCCGCTACCAGGGCTACCGCACCCACTACAAGTGGGACATCGGCCTGACCCTGCGCGACTGGCGCTATGTGGTTCGTATCGCCAACATCGACGTGTCCGACCTGACCAAAAACGCCAGCGCGGGCGCCGACCTCATCGACTTGATGACCCAGGCGCTCGAACTGGTGCCGAACGTCGGTATGGGCCGCCCGGCCTTCTACATGCCGCGCAAAATTCGCAGCTTCCTGCGCCGCCAGATCACCAACAAGGTGGCGGCCTCGACGCTGACGATGGAAGAAATCGCCGGCAAGAAGGTGGTCGCGTTCGACGGCATCCCGTGCCGCCGTACCGATGCGCTGCTGCTGACCGAGGCCCGCGTGGTGTAACAGGCCGGGGGCGGGCGACCGCCCCCGATCACGAATCCAGAAAGGAATCCCAGCCATGATTATCGACAAACTGCTCCAAGTCTCGGACGGCCAGGCCGTCACCGCGAGCGCGGCCTCCACCGACGTGATCGACTTCGGCCAGGCCAATCCCAACGTCGGCCTTGATGACCGCAGCAATATGGTCATCACCGTGGATGAGTCGGCCGCAGCCGCTGGCGCCGCGACCGTCAAGTTCTCGGTGCAGGACTCGGCCGACAACTCCAACTTCGCCGACGTGGCCGTCACTGCCGCCATCGGTAAGGCGAGCCTCGCCGCCGGCCAACAGGTCGTCATCCCGATGCCCACCAAGCTGCGCCGCTACTGCCGGGTGTATTACACCATCGGCACCGGCCCGCTGACCGCCGGCAAGTTCTCCGCACAGATCGTTACCGGCATCCAGCAGAACATCGCGCAGCCGGATAGCGCTCGCATCGCTTAATGAGGTGACAGCATGAAAGTGATTGCAACCAAGCTGGGCTATTTCGGAAAACTGCGCGAGCCGGGCGACGAGTTCGAGGTGCCGGACGGTACCAAGGGCTCGTGGTTCCAGCCGGTCGAGCAGAAGGCCAACGGCAAGGGCGGCAAGAAGCCCGAAGCCCCGGCCAGCGAGAAGCCCGCCGACGACCTGGTTTGATCTTCTCCAAGGTGGTAGCCAGCAGCTTGCGGGGGCCTTGCGCCCCCGTTTTTCTAGGAGGTGCCCATGGCCTCGGAAGTTGATATTTGCAACCTCGCGCTCGCGCACCTGGGCGACAACGCCACGGTGGCGAGCATTGACCCGCCCGAGGGCTCGGCCCAGGCGGAACACTGCGCACGCTTTTACGCCATCGCCCGCGACTGCCTGCTGGAAATGCACGCCTGGAAATTCGCCACCCGGCGCGTGCAGCTTGCCAAGCTGACCGTGCCGTCCTGGGACTGGTCCTTCGCCTATGCCGAGCCGACCGGCGCGCTCAAACTGCTGGGCGTGCTCTCGGCCACCGCGTCGAACGATGACGAAACCCAGCCATACGAGGCTGAAAGCGACACCAACGGCACAGCCATCATCCTGACCAATCAGGAGGACGCCAGCCTGCGCTTCGTCGCCCGCGTGACCGACACCACCAAGTTCTCGCCGCTGTTTGTCGATGCACTCGCCTGGCTGCTGGCGTCCTATCTGGCCGGCCCGGTGCTCAAGGGTGACGCGGGCGCTGCCATGTCGAAGGCGTGCCTGCAGAGTTTCTTGCTGGCCTTCTCCAATGCCAAGGTTTCGGACGCCAACCAGCGCAAGGTGCGCCCTGAACACACGCCCGCCTGGATCGCCGGGAGGTAAGCCGTGGCAAATATCCGCACCCTGCAACGCTCGTTCTCTGGTGGCGAAATAAGCCCGGAAATGTTCGGGCGCAACGACGACGCCAAGTATCAGTCGGGCCTTGCCCGCTGCCGCAACTTCATCACCAAGCCGCAAGGCCCGGCCGAGAACCGGCCCGGCTTCGCCTTTGTGCGCGCGGTGAAGGACTCCACCAAGAAGGTGCGGTTGATCCCCTTCACCTATTCGACGACGCAAACCATGGTCATCGAAATGGGGCCGGGCTACTTCCGCTTCCATACCCAGGGGGCCACCTTGATGAGCGGGGGCGTGCCCTACGAAATCGCCAACCCCTACGCCGAGGCCGACCTGTTCGACGTGCATTATGTGCAGTCGGCCGACGTGCTCACGCTGGTGCATCCCAACTACGCACCGCGCGAACTGCGCCGCCTGGGGGCGACCAACTGGCAATTGACGACCCTGTCCTTCGCGGCCTCGATTGCCGCGCCCGGTGCGCCCTCGCTATCGGCCGCCGGGCATACCTCGGTCAAGTACACCTACTACTACGTGGTCACGGCGGTGGATTCCGAAGGCGTCAGCGAGTCGGCCGCCTCGGCATCGTCGAGCGTGGGCGGCAACCTGTTCCAAACCGGCGCCACCGTGACAATCTCGTGGGCGGCAGTGACCGGCGCATCGCGCTACAACGTCTATAAGCTGCAAGGCGGCCTATACGGCTACATCGGCCAAACCACGGGCCTGTCCATCGTCGACGACAACATCAGCCCGGACCTGGGCAAAACCCCGCCCCTGTACGACAGCGTGTTCAACGGGGCCGGCGACTATCCTGGCGCCGTGTCCTACTTCGAGCAGCGGCGATGCTTTGCCGGCACGACCAACAAGCCGCAAAACATCTGGATGACCAAGTCGGGCACCGAATCGAACATGAGTTATTCGCTGCCGATTCGGGACGACGACCGCATCGCCTTCCGGGTGGCAGCACGCGAGGCGAACACCATTCGCCATATCGTGCCGCTCACCCAACTGCTGCTGCTCACGTCCTCGGCCGAGTGGCGCGTCACGTCGGTGAATAGCGACGCCATCACGCCCAGCACCATCAGCGTGCGCCCGCAGTCCTACGTGGGTTCGTCGAACGTGCAGCCGGTCATCATCAACAACACCCTGATTTACGGCGCCGCGCGCGGCGGCCACGTGCGCGAACTGGCCTACAACTGGCAGGCCAGCGGCTTCATTACCGGGGATCTGTCCCTGCGTGCGGCGCACTTGTTCGACACGTTCGACATTGTGGATATGGCCTATGCCAAGGCGCCGCAGCCAATGGTCTGGTTCGTTTCCACGTCCGGCCGGCTGCTGGGCCTCACCTACGTACCCGAGCAACAGGTCGGCGCCTGGCACTGGCACGACACGGACGGCGTGTTCGAGTCCTGCACCGTGGTGGCCGAGGGCGGCGAGGACGCGCTCTATTGCGTGATTCGCCGCACGATCAACGGTGCCAGCGTGCGCTACGTCGAGCGCATGGCCTCGCGTCAGTTCAGCGACCAGGCCGACGCCTTCTTCGTCGATTGCGGCGCCACATACTCGGGCGTGCCGGCCGACGTTATCAGCGGCCTGGGCCACCTCGAAGGCAAAACCGTCAGCATCCTGGCCGATGGTGCGGTGCATCCGCAGCGCGTGGTCACGGGCGGCAGCATCACCCTGGACATCGAGGCCAGCACGGTGCAAATCGGCCTGCCCATCGAGGCCGACCTTCAAACCCTGCCGCTCGCCGTGCAGCTACAGGACGGCAGCTTCGGGCAAGGCCGGTTCAAGAACGTGAATAAGGTGTGGCTGCGCGTCTATCGGTCCTCGGGCATCTTCGTGGGGCCGAGCGTCAGCGAACTGACCGAGGCCAAGCAGCGCACCACGGAAAACTACGGCGCGCCGCCGGCCTTGAAGAGTGAAGAAATCCCGCTTGTGCTCACCCCCTCGTGGGCCGATAGCGGGCAAATCTTCGTGCGGCAGTCCGACCCGTTGCCGCTCACAGTGGTGAGCCTGACGGCCGAGGTTGCGCTCGGTGGCTAGGGTGCGCGTATCCGAGGGGACGCGCATTACCTTGCTGCCATTCTCTCGGAGTTTTGAGCATGGGATTTTCCTCTAGCCAACTGGCATCAGCTTCGCTTATCGGCCAGATCGGTGGCGGGGTTACTTCCGCCATTGGCAGCTATTACAGCGCGGCGACGCAGAAGGCAACGATGCAAGGGCAGGCGGCGGTTGCCGATGTCAATGCTCGTATTGCCGAACTCGGCGCGCAATCCGCCCTTTACCAAGGCCAGCAGCAGGTCGGCGCCCTCACGCTCAACGCCGGACGTTTGAAGAGCCGGCAACGCGCGGCGCTTGCGGCCAATGGGGTGGATTTGGGCGAAGGCAACGCGGTGGAGATTCAGGCGTCGACCGACATCATGAAAACGATTGACGCCAACACCCTGACCGCCAACGCGGTGCGCAGTGCCTGGGGCTACCGCACCCAGGCCGTGAATTTCCAGAACGAGGCCCTGACCAAACGCGCGACGGCCGGCGCAATCAGTCCTTTCGGTTCGGCGGCGGGTTCCTTGCTGGGAAGCGCGGCCAGTGTCGCCGGTTCCTGGTACTCCCTCATCGAAGGGTAAAGCATGCCGCGCGTTCCAACCTACGACAGTTTCCAGGCCACGCCGAACACGTTGCCGCAAACCCGCATGACCATGCCGGAAATGCCGGACGTGGCCGGGCAGCAAGCGCAGCAAATGGGCCGCGCGATGATGGCAGGCGGTCAGCAAATCGGGCAGGTTGCCCTCGACATGCAGCAGCAGGCCAACCAGTTGCGCGTCGACGACGCCCTCAATAAAGCCAAGGAAGCCGCGCTGCGCTTGACCTACGACAAGGACGTGGGCTTCACCAACCTGCGCGGCATCAACGCACTGGAACGGCCGGACGGCAAGCCCCTGGCCGACGAATACTCCGACACCCTCAAGCGCAGCATTGACGACATCGCCGGCACCCTGGGTAACGACGCCCAGCGCCGGGCTTTCGCGCTCCATTCCAACGACATCCTGACCTCGTTCCGTGGTCAAGCTGTGCAGCACGAGGCCAGCGAGTACAAGACCTACGCGCTTTCCACGTCCGAGGGCATCCAGTCCACGGCGCTGCGCGACATCGCCCTGAACTGGAACAACCCCGACGCCATCAATTCGGCTGTCGATCGCATAAAGGCCGAAACCTTCCGGCAGGCGCAATTGCTGGGCAAATCCGCCGAGTGGCAGGAGGCACAGGCGCGCAAACTGACCAGCAACGCGCACAAGATTGCGCTCATGTCGGCGCTGGAACAAAACAACCCGACCTATGCCTCGGCCTACCTCAACAAGTATTCCGGGCAGATGGACGCCGACGACATCCTCACGGTGCGCGGTCATATCACCAAGGACATGGACGGCCGCGCCGGACTTGCTGCCGCTACCGATGCTGTCGGCAAGGTTCCCATCCAGGTGAGCGATGGCGAGCGCGCGTTCAACATCGCCGTGGGCACCGAGTCAGGCGGCCGACAGTTCGGCGCGCACGGCAAACCGCTTACCTCGCCCAAAGGCGCGGTCGGCATCGCCCAGGTCATGCCCGACACCGCGCCCGAGGCCGCCAAGCTGGCGGGCCTGCCGTGGGACGAGAACCGTTACCGCAACAATGCCGCCTACAACCGCGCGCTGGGCATGGCCTATTTCCAGAAGCAATTGCGCGACTTCGGCGGCGACCTGCCGAAAGCCTACGCCGCCTACAACGCCGGCCCCGGCGCGCTGCAATCGGCGCTGAAAGACGCCAAGGACGGCAACTGGCTGGCGCTACTGCCGAAGGAAACGCAGGACTACGTGGTCAAGAACATGCAGGCGTACAACGCCGGCCAAGGGCGCCCAGCGCGGCCGACACTGGCCGACATCGAGGCGCAGTTGCAGAACGACCCACGCCTGGCCGGCAACCCGGAACGGCTCAAGATTGCGCGCGTGGAGGCCGAGCGCCAATTCAACATGCAGACGGCCGCACTCAAGCAACGCGATGACGAGGCCGTCGTCACTGCGCTGCGCGGCCTGTACGAGAACGGCGGGCGGTTTTCGGAACTGCCGGTGTCCATTCGCGCGAACATCCCGCCCGAGAAGCTGACTAGCGTTATGGGCGCGGCCGAGCGCATCGCCAAAGGCGACGACACCACGAGCCTGTGGCTCTACAACAAGCTGACCAACAGCCCGGACGAGTTGGCGCGCATGTCCGACAACGAGTTCTACGCACTTCGCACCAGCCTGTCTGAGGCCGACTTCAAGCATTTTTCCCAGGAGCGCGCCAAGCGTCTGGGCGCGGCACCCAGCACCAACGGGCCGGGCGACTTGAACAGCCAGGCTATCAAGGCGGGCCTCGACACGCGCCTGCGCATGATGGGCGACGACCCGACGCCAAAGGACGGCAGCAGCGATGCCGAGCGCGTCGGCGCCATGCGCAAATTCATCGACGGCTATTTCATCGCCGCGCAGCGCGAGGCCGGCAAGAAATTCACCGACGCCGAGGTCGAGCAGCACCTCGACGCGCTGTTCATGAAAAACGCCACTGTGCGCGGCTGGTTCTCGAACTCGTCCGTTCCGATCTTGAGCATGAAGGTGGGCGACATCGACAGTACCACCAAGGACGGCATCAAGGCCGCGTACAAGCGCGCGGGCATCGACTCGCCGACCGACGCGCAAATCCTCAATGCGTACTGGAATTTGAAGGTTTCTCGTAAATGA

Protein sequences of DBSCAN-SWA_1

>NC_018828|1715779:1774980|1757106_1757289_-|WP_164926499.1|DBSCAN-SWA
MDRSQYHHCANLFVEIAKAQPALIQSSGHGALAGKRLAEMAWAFIDEFNRQYEEKVTPND
>NC_018828|1715779:1774980|1763610_1763754_-|WP_164926502.1|DBSCAN-SWA
MSVNWAHSTRGATGALEAAQAHCAKYGRHAQFAGKVTDFELAYNCVK
>NC_018828|1715779:1774980|1753706_1753946_+|WP_080700710.1|DBSCAN-SWA
MSRWKRPLTCKEVKKILANLGFSHRSTEGSHENWIKQGNLRRWKVTVDCPKAPFSDFLIKSMASQAGVTVKQFYAALDK
>NC_018828|1715779:1774980|1720805_1722701_+|WP_015039415.1|DBSCAN-SWA
MRVRGHGFTLAPFDATAGASGRGAGYKVNKMGKTVRGGAAAILGGWVNDITPGTLRADAQAGLLGALLVLPQGVAFAMLAGLPPEYGLYSAIVPCIVAALFGSSRHVLSGPTNANSLALFAVLAPLALPGSPGYIQMALAVTILVGVMQLAVGLLRLGSLANFISPSALFGFTSGAALLIAVHALKDALGLEGVQAHSAGAVLAAVGSRLGEAHWGASAVALTTIIVTLLVRHWDRRKPHMLAGLAAGTLLAAALNAGVFAAAGQPISVLGALAQPWPPFHVPAVQWSVLPDLVGVAVSLTIVALAQSISIAKAVAMRSGQLIDANREFIGQGLSNVVGGLFSSYLSCGSLNRSVPNYEAGARTPMAAVFAALLLVLLVLVSSPVLALIPHAAIAGLLIVVAWSLLDLPRWSVLVRIAPREALIAAATLAATVTIRMEIAILLGTLLSLTAYLYRTARPAMRPMGFDAADPQRHFAVLEGQPGELPECPQLKLLRMEGSVYFGAATHVTDRLQALRAGASAGQRHLLVMSKSMNFIDHAGAQVWEEELRRRRAGGGDLYFHRPRPEVLRDWRRSGFIDRLGADHIFPDKATAIHTIYERLDPEICRGCTARIFTECGPPGTAHQPSAERDE
>NC_018828|1715779:1774980|1760927_1761098_+|WP_165446306.1|DBSCAN-SWA
MKNRQPVQTTLPPEAMRLLQQAAQTPITRADPLARVKAIEKATERVKRQYPQFFKE
>NC_018828|1715779:1774980|1723045_1723282_-|WP_003810297.1|DBSCAN-SWA
MARVCQVTGKGPMVGNNVSHANNKTKRRFLPNLQSRRFWVESENRWVRLRVTAKAIRTIDKNGIDAVLADLRARGEAV
>NC_018828|1715779:1774980|1726721_1727723_+|WP_003810304.1|DBSCAN-SWA
MRFTPVKTLAALAALCAFSGAAQAADQPQCEVSRPVNFGGMNWESNLVLVDIERFIMEKGYGCKTEVLPTETLPALAALERGDLDINTEIWLNSVADPWDRAQKTGKVKRVGELYMGGEAWFVPRYTAERLPELKSAADLPKFKDRFKDPEEPGKGRFYGCPAGWGCEVTSTNLFHALKLDDSYTLYSPGTGAAQKAALMSAYKRKQDVVFYYWYPTPLVGSMDLVKLELPPYDAEKHKCLTAPKCSDPQPSAYPENPVFTAVNTRFSEEAPKLTEFLSKVAVPLPVMDQTLAHMEESGDESGAVAQWFLKNQADVWKKWVPADVAERVQTAL
>NC_018828|1715779:1774980|1738415_1738928_+|WP_003810321.1|DBSCAN-SWA
MKSLIALALAAMSGVAAAQSVEMSLLSPKGDDQKIGQIKYEQTDYGVLFTPDLHGLAPGVHGFHLHAKPSCAMTKVDGKDMVGGGAGGHWDPDNTGAHKGPYDKTGHKGDLPAVYVTADGKATYPVLAPRLKVADLAGHALMIHVGGDNYSDHPAALGGGGGRMACGVVK
>NC_018828|1715779:1774980|1727895_1728753_+|WP_003810306.1|DBSCAN-SWA
MFPEVIPARAVRGAIDGFVDHLVTNYADTLEAMSQPFLSVLVWLEQVLRQSPWWAVVAVTIAIAWLVSRRIGLSLAMGALLCVIGVLGLWDAGMQTLALMIMAAGLSVVIGIPLGVLMARVDWLRAGMLPVLDVMQTMPSFVYLIPVVMLFGLGKIPAIIATVIYAVPPLIRLTDLGIRLVDREVLEAARAFGANPRQQLFGVQLPLALPNIMAGINQTTMMALSMVVIASMIGARGLGYEVLLGINRLEVGRGLLAGLGIVVLAVLFDRITQSYGQRVRTGGQR
>NC_018828|1715779:1774980|1754580_1755255_-|WP_033448667.1|DBSCAN-SWA
MAGEVVVLSTHEEALQFLQTLLDPDSSEDSLPEDIDIKGELASMLIEIEGTNYHSSVTGNLSRGLWELQQEIYRAVAATLHGAPNIKRLTKEELHDYNLVIDVEDGCSKLVADLKDIVGHLKDAVNSMESRHKLIFLVTTVVALTAGTGLTWIKNNEIAADKSVRVEQEKTAQMEVVRKAAQEVPALERWVQASENGARSIAKSVSDADSLSIGIYCSRSGCSK
>NC_018828|1715779:1774980|1748527_1749175_-|WP_015039432.1|DBSCAN-SWA
MNRYILSPHEQGSDGWLLDRCGRVTGSRAADMLAMTAKKEWSTKRADYKFELAIEVLTGMPQGSDYTSKEMQWGIDQEPFARMAYEEASGNVTIESGFMYLPDVAAGCSVDGLFVEDGRRGVLETKCPKSTTHIRYLEAGTLPDQYRPQCLHNVWVTGAEFADFVSFDPRFPQELQLFVCRFTPTAKELADHEKAVLQFLAERDELVAQLKRLAA
>NC_018828|1715779:1774980|1754069_1754564_-|WP_015039439.1|DBSCAN-SWA
MKLLNEALQKSLAQNEAMQLRLLQTVDKMVEALQPAVKQAHVPIGRSVQTISVYQQGTPAPATVLDRASKELANAPKDTSITETHPYVGVISELDMLSGNCKVSLDGFPPDERINAVITDPVVQRADNAYVVAMARISPVAFLAKAEIDAEGEIVRLHISDLSA
>NC_018828|1715779:1774980|1768924_1769347_+|WP_015039459.1|DBSCAN-SWA
MIIDKLLQVSDGQAVTASAASTDVIDFGQANPNVGLDDRSNMVITVDESAAAAGAATVKFSVQDSADNSNFADVAVTAAIGKASLAAGQQVVIPMPTKLRRYCRVYYTIGTGPLTAGKFSAQIVTGIQQNIAQPDSARIA
>NC_018828|1715779:1774980|1758817_1759573_+|WP_015039446.1|DBSCAN-SWA
MHSRDVSAFAELLAGVFDAYNRLPPQPATQLLWLRMLEPYEFPAVSAAFSQYVANEVKFPPTPAQILALLGHGTGDSRPTADEAWATALVSRDEAETVVWTLETAQAFAACRTVLDLGDEVGARMAFKGAYDRLVARARHDRQPVAWQVSLGWDPDRRERALTAAGTAGLLPAPHVAALLPPPDPSGGLGDDAVAAENIARLRKLLAGALSPSEKRRRAAEQAGQAERDRLDVLKAETAAKVAQHQQGVRA
>NC_018828|1715779:1774980|1767873_1768869_+|WP_015039458.1|DBSCAN-SWA
MPTLSTTNPTLADVAARMTPDGKIDPQIVEMLNETNEILDDMTVIEANGFTEHKTTVRSGLPTGTWRKLNYGVQPEKSRTVQVKDSMGMLETYAEVDKALADLNGNSAAWRLSEDRAFIEGMNQTQATTLFYGDSSIDAEKFMGLTPRFNSLSAENGQNIIDAGGTGSDNASIWLTVWGPNTLHTIYPKGSQAGLQSSDLGEDTLIDAAGGRYQGYRTHYKWDIGLTLRDWRYVVRIANIDVSDLTKNASAGADLIDLMTQALELVPNVGMGRPAFYMPRKIRSFLRRQITNKVAASTLTMEEIAGKKVVAFDGIPCRRTDALLLTEARVV
>NC_018828|1715779:1774980|1747179_1747539_-|WP_015039429.1|DBSCAN-SWA
MTDLELLILSAKAAGIEVWPGTGFQAHMLFTRPAKADPHGKVAGIEWNPLTDDGDALRLAVKLRLWVHVDDYGGSARRPGDTWFGCAAHKYGGIEAATRRAIVRAAAEIGAKMQEAAHA
>NC_018828|1715779:1774980|1750949_1751849_-|WP_015039435.1|DBSCAN-SWA
MSDTKATLKFEVTLADLRRDGACFEGYNKVVRAVQGREFSDDDSARESYIKFSHAEPVALTAIIASNGLDDALWALRCVPGVDRHARLFAVWCARQVEHLMTDQRSKDALDVAERFANGEATEEERDAASAAARAAASADASAAAWDAAWDAARAAASAAAWDAAWAAAWDAAWDAAWYAARAAASAAARAAASAAARAAARAAARAAASAAARAAAWDAAWDAAWDAARAAASADARAAASAAARAAARAAASAAARAAAWDAARAAARAAALGAARDAQKEMFIAMCEGRAPWQQTT
>NC_018828|1715779:1774980|1742346_1742937_+|WP_015039427.1|DBSCAN-SWA
MQIVKLLTVSVAAGLLAGCASGPTLRSDYDHSANFAQYRTFAFMSPLGTDRAGYSSLLTERLKQATRGQLEMRGYTYDESKPDLLVNFNGKLQEKNQVTPAPPPMGPYYGYRAGFYGGWPGYGWGDDVYQYTEGTLNIDLIDARRRQLVWEGVATGEVNDLDKAQSAASVEQGVAQIFSKYPFRAGNGQPQTPPKP
>NC_018828|1715779:1774980|1764375_1764837_+|WP_015039454.1|DBSCAN-SWA
MSGLVAAESRIPAMTAQAIDKVRELEAITRDLPQVEIATDHVLHGGMYARTICIPAGVVLTGVFIRVPTLLVFDGNATVNAGDDATTLVGYHVLAASAHRRQAFLAHADTRLTMVFATQAKTVAEAEDEFTDEAHLLFSRKPGAVNRINITGE
>NC_018828|1715779:1774980|1722814_1722982_-|WP_003810296.1|DBSCAN-SWA
MAKGIREKIKLESTAGTGHFYTTTKNKRNMPEKMLIKKFDPVARKHVDYKETKLK
>NC_018828|1715779:1774980|1757655_1758030_+|WP_015039444.1|DBSCAN-SWA
MQREQGVGLDFLRIRPSEPMLFIDKAEIARCVTYRQAVRLAWDMRQPRGMTMRTLAELCGMYPQHVSSYLHEDPLLPSSFAKPSPSAFSIELMGWSLRTLSDIRDSLVGWALSFAQRCGRDVRS
>NC_018828|1715779:1774980|1764839_1765154_+|WP_164926504.1|DBSCAN-SWA
MSGAATGVMAVAAVAATAIAYNNGQQQKKAAKKARQQAEANAKKQEKAADEATNRANTKRADTGAALDWATQAGKAGASGTMLTGPQGVDQSALTLGKSTLLGQ
>NC_018828|1715779:1774980|1765155_1766823_+|WP_015039455.1|head,tail|DBSCAN-SWA
MAEQTERKLLLSRWGQLRTERESWMSHWKEISDYLLPRAGRFFVDDRNRGDKRHNNIYDSTGTRALRVLAAGMMAGMTSPARPWFRLTTSDPQLDESAAVKAWLADVTRLMQMVFAKSNTYRALHSMYEELGAFGTAGAIVLADFNSVIHHYTLTTGEFAMAADHRGQINTLYREFQMTVAQMVREFGRDNCSPTVQTLFDRGALEQWVTIMHAIEPRVDRDVTKRDDRNMAWKSVYFEHGGNEDQILRDSGFKEFPALCPRWATSGGDIYGNSPAMEALGDIKQLQHEQLRKAQGIDYKTKPPLQAPTSLKSRDVDTLPGGISFVDSAAPNGGIRSAFEVNIDLSHLLADIQDVRERIKGSFYADLFLMFANGTNPQMTATEVAERHEEKLLMLGPVLERMHNEILDPLIEMTFSRMVEANIVPPPPDELQGMELNVEFVSMLAQAQRAIATNSVDRFVGNLGAVAGIKPEVLDKFDADRWADAYADMLGIDPELIVPGEQVALIRKQRAEAAQAQQQAALLNQGADTAQKLGSVDTSKQSALTDVTRAFSGYT
>NC_018828|1715779:1774980|1761285_1761528_+|WP_164926501.1|DBSCAN-SWA
MQKTVAVNERGLRIGQDHQNARYTNGEIEMVLTLRDDGKSYGEIARLVEMPKSTVRDICTGRRRCQYAANFKTVRVPDGQ
>NC_018828|1715779:1774980|1723651_1724797_-|WP_164926688.1|DBSCAN-SWA
MGALTAIGPFSIDMYLPAFPSIAAGLGVERGEVERTLAAYLIGMAGAQIIYGPLADRYGRKLPMMGGLILYVLASLGCALAGDIQTLTAWRVAQALGGAAGVVIPRAVIRDHYETQEAARAMSLLMLIMGLAPILAPLAGAQLLAFVGWRSLFWLMAAGGLALLLAVALTMKETLAPERVLPLRAGTILSNYRALLAHRGFMGHSLAGGMGQAGMFAYIVGSPRIFIELYGIAPQYYGLLFGANAAALIVGSQISARLLRKSAPATLQRHAQVALAVASLSALALALLGLMSLPLLMACLMGYMFSQGFVNPNSAALALAEQGRRLGAASALLGTLQLSCGALAGLIISIWPAESVLPLAAVLAGSACLSWQFGRMARRPA
>NC_018828|1715779:1774980|1735532_1737074_+|WP_015039421.1|DBSCAN-SWA
MSNANLYAVLEGGFPADRDRVALETPTLRYTWNDIDRASACLANLLASLKLPAGARVAVQVEKSPEALLLYLATLRAGLVYLSLNTAYREAEIEYFLGNAEPAVVVCTSANAGWVRRAAAKAGSAHVYTLDEDRTGTLLQAAAAMPQRFRTVARKADDLAAILYTSGTTGRCKGAMLSHGNLASNARVLHQYWGWREDDVLLHMLPIFHVHGLFVASHGALLAGARMIWLPRLDVDQALRYLPQSTVMMGVPTYYVRLLADARFDRAACANMRLFISGSAPLLTETFADFQARTGQTILERYGMSETVMLTSNPCRPADGERLGGTVGKALPGVQVRVVDDAGQALAAGEIGNVQVRGPNVFSGYWRMPEKTREEFTADGWFKTGDVGRWGGESGGRAVPADYLSIVGRSKDLIISGGYNVYPKEIETVIDEMQGVLESAVIGVPHPDFGEAVVAVVVPRAGAAIDVAAMQADLKSRIANFKVPKRIHVVDQLPRNTMGKVQKNVLRDTYAAS
>NC_018828|1715779:1774980|1763917_1764379_+|WP_164926503.1|DBSCAN-SWA
MEPTIRTITVDEAFDSPVFAALCDEYRAESLRNPDMMGALPDREGYARMVDAGLLHPLGVFVGEELVGMCAVLIAPVLHFGGKVVASTETLFVAEAHRAGGAGLKLLHAAEEVAAEAGAGGLYVTAPAGGRLERLLPRVGYHETNRIFFRGLL
>NC_018828|1715779:1774980|1769359_1769542_+|WP_164926506.1|DBSCAN-SWA
MKVIATKLGYFGKLREPGDEFEVPDGTKGSWFQPVEQKANGKGGKKPEAPASEKPADDLV
>NC_018828|1715779:1774980|1766866_1767214_+|WP_015039456.1|protease|DBSCAN-SWA
MSNYDPTDIRSQERAKADTDLRNRLAKDTEESDLKWLMGSKRGRCIVWRFLDRAGVFRLSFNTNSMTMAFNEGNRNEGLRILAQIHTLCPELYPVMVKEQIHDNRNADDGSRNDH
>NC_018828|1715779:1774980|1772856_1774980_+|WP_015039464.1|DBSCAN-SWA
MPRVPTYDSFQATPNTLPQTRMTMPEMPDVAGQQAQQMGRAMMAGGQQIGQVALDMQQQANQLRVDDALNKAKEAALRLTYDKDVGFTNLRGINALERPDGKPLADEYSDTLKRSIDDIAGTLGNDAQRRAFALHSNDILTSFRGQAVQHEASEYKTYALSTSEGIQSTALRDIALNWNNPDAINSAVDRIKAETFRQAQLLGKSAEWQEAQARKLTSNAHKIALMSALEQNNPTYASAYLNKYSGQMDADDILTVRGHITKDMDGRAGLAAATDAVGKVPIQVSDGERAFNIAVGTESGGRQFGAHGKPLTSPKGAVGIAQVMPDTAPEAAKLAGLPWDENRYRNNAAYNRALGMAYFQKQLRDFGGDLPKAYAAYNAGPGALQSALKDAKDGNWLALLPKETQDYVVKNMQAYNAGQGRPARPTLADIEAQLQNDPRLAGNPERLKIARVEAERQFNMQTAALKQRDDEAVVTALRGLYENGGRFSELPVSIRANIPPEKLTSVMGAAERIAKGDDTTSLWLYNKLTNSPDELARMSDNEFYALRTSLSEADFKHFSQERAKRLGAAPSTNGPGDLNSQAIKAGLDTRLRMMGDDPTPKDGSSDAERVGAMRKFIDGYFIAAQREAGKKFTDAEVEQHLDALFMKNATVRGWFSNSSVPILSMKVGDIDSTTKDGIKAAYKRAGIDSPTDAQILNAYWNLKVSRK
>NC_018828|1715779:1774980|1762022_1763618_+|WP_015039452.1|terminase|DBSCAN-SWA
MSSVAEIRRLMAYMTPAELAEVDALLATAPPWLPLPGPQTAAYNSDADIIGYGGAAGGGKTDLIAGLTLTKHERALIVRREKAQTEGFVQRMTEIMGGTDGYNSQKGFWRLPGGRLCELAGLDNPGDERRWQGRPHDLKAFDEVTEQREQQVRFVMGWNRTNKPGQRSRVLMTFNPPTTSEGRWVIDFFAPWLDKKHPLYPTAPGALRWVAMLPDGNGGSRDTWFDSDGNPLSSAPFVLVGGRVEYDFDPADYNPEDIIQPKSRTFIPARVTDNPYYVDSGYLVTLQSLPEPLRSQMLYGDFNAGIEDDPWQVIPTAWVEAAQARWKRPDRLAPMDSLGVDVARGGRDNTILARRHAMWFDVPLTYPGKDTPDGPTVAGLAIAALRDHAVIHLDVIGVGASPYDFLNEAGQQVVGVNVAESAVGTDKSGRLRFKNLRSELWWRMREALDPTNNTGIALPPDSRLLADLTAPTWSLSGATLKVASREDIIEKIGRSPDFGSAYVLALMDTPKRSVVEAMGQRRRRDYDPYAT
>NC_018828|1715779:1774980|1730559_1731741_+|WP_164926496.1|DBSCAN-SWA
MNEVVVVAAARTAIGDFGGGLKDVAPCDLGATVIREALARAGVAGPEVGHVAVGHVINTEPRDMYLSRVAAINAGIGKETPAFNVNRLCGSGLQAIVSAAQTIMLGDTEIAVGAGAESMSRAPYIAPAQRWGARMGDSAMVDMMTGALSDPFGRMHMGVTAENVAARYSISRADQDALAVESHRRAAAAIDAGRFRDQIVPVTLKTRKGETVFDTDEHVRRDITIEGMAALRPVFQKENGTVTAGNASGLNDGAGAVVLMSAAAAAQRGIAPMARLVAYAHAGVDPEIMGIGPVPATQAALKRAGLTVDQLDVIEANEAFAAQACAVTRQLELDPAKVNPNGSGISLGHPIGATGAIITVKALYELQRVGGRYALVTMCIDGGQGIAAIFERV
>NC_018828|1715779:1774980|1741882_1742236_-|WP_015039426.1|DBSCAN-SWA
MSAPSLQLDGTLWLRSGDQPWGGQHRIDLLAQIEATGSISAAARAAGMSYKDAWDAIDAMNNLAGEPLVLRSAGGRGGGGTLAAIITEESARDLALAAGTPVCALFDAASVMLGVLD
>NC_018828|1715779:1774980|1746812_1747067_-|WP_164926498.1|DBSCAN-SWA
MAHAAQHQAPDPVSPTRTAMKWVKINKYCELSGDTPDAIYAKNRRKIWTEGVHYKKAADGCLWINLEEVDKWVEQDQSQSRRAA
>NC_018828|1715779:1774980|1733422_1734724_+|WP_010928183.1|DBSCAN-SWA
MSALDPQASARVARTPDAEPEAVDASAAGESAGLIARLGRLFERDRLPPPADLAQLFEARLTDVRANKLAQAWRLAYEQADGKRRRAMLGGLAQVGAGMQGDGAQGTRLFKRFNALPDGLRFLVALRADMLRWRKQVAGLQALDKELEALLSAWFDVGLLELRPLTWDSPASLLEKLILYEAVHEIRSWDDLRHRVAGDRRCYAYFHPQMPDVPLIFVEVAFSAQMADNVQALLDTSAPPQDLDKARWAIFYSISNTQPGLRGISFGNFLLKRVIDRLLQELPKLKFFATLSPIPGFADWLSRLDAQEVEQAVRDKARTRSGAPDGARWVARLARAATGKPSEVVQRAGLRLAARYLQAMRAGQPLDPVARFHLGNGARIERLNWAADTSAKGLAQSCGMMVNYLYELGDLDGNLARLNEGKPQVSRGIARLG
>NC_018828|1715779:1774980|1759569_1760046_+|WP_015039447.1|DBSCAN-SWA
MSSYAEASAAVGGNESGGYGVCAAYGCCLPGTMTDSTRGGKDWHCRLHFGAPRSEFDDISARVQNRKALFLAAYWLVNRSKGDTVSRKVRDRIKALGRADLLEKVPSVRGVTAYHLGVHMLRVLGDECRQPQEHMGTPKRAGQGTTWLDQTQPEETDA
>NC_018828|1715779:1774980|1751887_1752772_-|WP_015039436.1|DBSCAN-SWA
MNFEIKNRWTGAVLFTADVPDETESGMVARVALEQAVKSGANLARADLAGANLAGANLADAYLADADLAGANLARANLARANLAGANLADAYLARAYLADAYLADAYLADADLARANLACANLAGADLAGADLARANLAGANLAGAYLARANLAGARNLPVGTEATSPVEPYQRDTRPAAERNAARAARFRELNPTVPVVEALDAKILSAIENGRGGLEMGAWHTCETTHCRAGWAVHLAGEAGYALEREHGPQYAGRMIYMASVGRAPHFFASNELAMADLREQAAQQTKPVA
>NC_018828|1715779:1774980|1715779_1718437_-|WP_010926800.1|tRNA|DBSCAN-SWA
MQERYQPNSVEAAAQQTWQARDAYLVHEHAKNPDGSEKPKFYACSMLPYPSGKLHMGHVRNYTINDMMARQLRMRGYNVLMPMGWDAFGMPAENAAIKSKVPPAKWTYDNIAYMKKQMKAMGLAIDWSREMCACDPKYYKWNQWLFLKMLEKGIAYRKTQVVNWDPVDQTVLANEQVIDGRGWRSGAPVEKREIPGYYLRITDYAEELLDQVSTNLPGWPERVRLMQENWIGKSEGLRFAFPHRIAGADGKLIQDGKLYVFTTRADTIMGVTFCAVAPEHPLATHAAQSNPALAAFVEQCKLGGTTEAEMATREKEGMPTGLTVTHPLTGAEIDVWVGNYVLMTYGDGAVMGVPAHDERDFAFARKYGLPIRQVVALEGKTYSTDAWQEWYGDKQAGRTVNSGKYDGLAYQAAVDTIAADLAAQGLGEKQTTWRLRDWGISRQRYWGTPIPIIHCADCGPVPVPEQDLPVVLPDDLIPDGSGNPLAKNEAFLSCSCPRCGKPARRETDTMDTFVDSSWYFMRYTSPDNDQAMVDARNDYWMPMDQYIGGIEHAVLHLLYARFWTKVMRDLGLLNFDEPFTKLLCQGMVLNHIYSRKTPQGGIEYFWPEEVDNVYDAKGAIVGAKLQRDGSEVNYGGVGTMSKSKNNGVDPQSLIDTLGADTARLFVMFASPPEQTLEWSDSGVEGANRFLRRLWALGYAQREAVGRGLATGADWAQAPAPVKELRREVYGLLKQADYDYQRIQYNTVVSACMKMLNAIDDAPLPEGPAADAARAETLGLLLRVLYPVVPHITWHLWQDLGYAEHLGDLLDAPWPHVDEAALVADEIELMLQVNGKLRGSIRVAAKAPKEDIERIAAAQEEVARFLEGRPPKRVIVVPGKLVNVVG
>NC_018828|1715779:1774980|1725013_1726270_+|WP_033447541.1|DBSCAN-SWA
MLSVVERKLQELPVPVQLTLPDGTVLGSPEARVRFVARDKTALAHLAEGAVGVLGQDYVEGRIDIQGSMRDVMAAAAALLPSSPVDAARGGWLTELVRKVTSVWRHSIERDARQIEFHYDLSDDFYALWLDPRRVYSCAYYRTPDMTLAQAQEAKLDHICRKLRLQPGERFLDVGAGWGGLLLWAAENYDVDATGITLSRNQHAYVNRLIEEKGLSGRVRMELLDYRKLDEGAPYDKIASVGMFEHVGRAQLPGYFAKLRRLVKPGGLVMNHGITAGGVYNAELGNGMGEFIEKYIFPGGELTHISSVLEAVTAGGLEAVDDENLRPHYARTLWAWSDALEACLPEAARILQGEQGERSLRAYRLYLAGCAMGFEHGWISLHQVLVTTPATGRTDELDMARDLAYPWRRDYIYAGNAR
>NC_018828|1715779:1774980|1761534_1762026_+|WP_015039451.1|terminase|DBSCAN-SWA
MGSMKLTPEKLTAFCAALAETCNVGRACAAVGISRQTAYNWREADADFALAWERAMKAGLLALEDEAHRRAFEGTDEPVFYKGDECGSVRKYSDTLAIFLLKAHAPDKYRENTRMELTGANGGPVQINDTERAARIAAIVAAAQQRAQRAAAGEDDDPAAGLV
>NC_018828|1715779:1774980|1718514_1719384_-|WP_015039414.1|DBSCAN-SWA
MSPARARLTAPIVLLMSVATGLAVASNYYAQPLLHTIGAEFALTTATAGAIVTVAQLSYAVGLILLVPLGDLYERRTLIALMTALSAVGLLLSAFSPGIGWLMLGTAVTGLLSVVAQVLVPFAATLAEPHERGKVVGAVMSGLLLGILLARTIAGALADLGSWRTVYWVAAILMLLASWPLLAWGAHHVAPLLAGVLALDLAIQAVHVTNQSAIYRLRPEARSRLTAGYMTSYFLGGAAGSLLSAWIYAHAGWLGVTAAGALTSLAALLYGCLARSARIPETTPAPAIA
>NC_018828|1715779:1774980|1748028_1748409_-|WP_164926388.1|DBSCAN-SWA
MHFDSNTKKNDQPSATLQFTYRTSNDVLSEFSPDLKSSLYRRPRQDEGDMADNADPRLDDPGYLPCLKFPNMQNKVALSEKVVGATVTVHHGIGGKSDLNMDFRAMPFADNSFSLVARKEGDGNAN
>NC_018828|1715779:1774980|1772328_1772853_+|WP_164926507.1|DBSCAN-SWA
MGFSSSQLASASLIGQIGGGVTSAIGSYYSAATQKATMQGQAAVADVNARIAELGAQSALYQGQQQVGALTLNAGRLKSRQRAALAANGVDLGEGNAVEIQASTDIMKTIDANTLTANAVRSAWGYRTQAVNFQNEALTKRATAGAISPFGSAAGSLLGSAASVAGSWYSLIEG
>NC_018828|1715779:1774980|1732707_1733472_+|WP_015039419.1|DBSCAN-SWA
MTTPIVRQALYLEVADRLRTMIRTHALGAGTWVDEAGLTEQLGISRTPLREALKVLATEGLVRLEPGRGCFVNELTVRDLEQIFPLMAMLEGRCAFEAAQRAGDDDLRALEPLHRALQAHAQAGRIDAYYETNYCIHVAVQTLADNRWLSDMVDNLRKVLSLFRHKSLALPGRIRESCAEHMAIFAALKARDPEGAEALTRKHLLRQLAALQALAGQEPAGGAAAIDSPAVQAVQELNHVRTRSPGIRTRRTHA
>NC_018828|1715779:1774980|1731823_1732594_+|WP_010930714.1|DBSCAN-SWA
MPIRYTPSELDQPSLSEADGIRYLHFGTEWVQGAMLIRDPARLVLEYTAQMMAWLLFLEPPREQSIGLLGLGAGSLARFCLKHTRSPVTVVEWNPQVTAVCQMFFRLPTPQRLDVHHDDAGAWVADPARAGDCPVLMVDLYDAQARGPVRDSVKFYRDCRRVLGEVGVLSVNLFGRHESYGRNIDNLSKAFDDRLVLLPEIDAGNQIVLAFSGPPLAITPAELLARAETVEAQYGLPARRWARALTRHAVDGVLHF
>NC_018828|1715779:1774980|1767170_1767860_+|WP_164926505.1|protease|DBSCAN-SWA
MTTETLMTEAATTTEGQPASQPAAEQSATGAGNDGQQQQQPTQEQGTQGQQPAAGAAKTEGDDKAKPQGAPEQYEFQAPEGVAFDDGVLGAFSEVAKELDMPQDKAQLVLDKMLPVMQARHAEQVGEFYADIGGLPETWVASSTADKEFGGDKLQENLATAKKARDAFGTPELTTLLNKTGLGNHPEIIRVFYRAGLAISEDRLVAGNNGNQPKQGDARRLYAASNMNP
>NC_018828|1715779:1774980|1730112_1730487_+|WP_010926797.1|DBSCAN-SWA
MPLLNVQIMQGHQPAQKSALLAAACQAVVDSIGAPLASVRVVLEEVPAAHVIVAGELGRQMALVTVDMIAGRTDEQKEALIGALNRAVCDSIGIDGADVRVMIHDVSKANMGVANGISARAAGR
>NC_018828|1715779:1774980|1734732_1735527_+|WP_165446305.1|DBSCAN-SWA
MKPNSQPGQILCRIDAGVAHVTLSHPGRMNAMTVAMWRQLREVFEALGADAALRCVVVAGAEGHFAAGADIREFPAERADLAGVQRYHREILAQALAAVAACPHPVLARIEGVCVGGGLEIAAQYDLRIAAESARFGVPIGKLGFPMAPDEMRGLLDLVGRAATLAILLEGRVFDAAEALRLGLVTRTVPVAELDQAVQRSVAAILGGAPLAARINKRQARRLCAGAPLGEDEYLDFFSYAESRDHRESVRAFLAGTAPTFTGD
>NC_018828|1715779:1774980|1744161_1745382_-|WP_015038907.1|transposase|DBSCAN-SWA
MLDRKLLESLGSWQGYGVERVEWPEDPGRTLSIYLKPTAKVMLCEQCGARCRQVHETTVRRVRDLPLFEYRVVLHVPRRRLWCEQCGGPRLERLAWLGRYQRVTDRLAQACSQLLQSSNVQAVARFFELGWHTVKTLDKARLRASVREPDWSKIEYLAMDEFALHKGHRYATVVVDPIGRQVLWIGPGRSRETARAFFEQLPPGAAQRIKAVAIDMTTAYELEIQAHSPQAEIVYDLFHVVAKYGREVIDRVRVDQANQLRQDRPARRIIKSSRWLLLRNRDNLDRQQAVRLDELLQANQPLLTVYVLRDELKRLWFYQRPAWARQAWNHWYEQAEQSGIPALNTFAQRLKGYLHGILARCRHPLNTSIVEGINNTIKVIKRRAYGYRDQEYFFLKIRAAFPGNAR
>NC_018828|1715779:1774980|1750340_1750718_-|WP_010926411.1|DBSCAN-SWA
MLPLTYPTECGTAAVVRPLTDAERLAELRRDLDADLHYALVAQRCVRWPYGDPELVAEALYAATIGDAQSEAAFSLLVRAAARGESAVSVGTLFVEWTKLARARLLDTLVELTEDGQRVTFGSRQ
>NC_018828|1715779:1774980|1739086_1740061_+|WP_015039423.1|DBSCAN-SWA
MLIGKKHFLTVGALALAMAIHAAPVMAQQKSVAITAIVEHPALDSVRDGVQDALKQAGYESGKNLKWQYQSAQGNTGTAAQIARKFVGDRPDVIVAIATPSAQAVVAATKDVPVVYSAVTDPVAAQLVPSMEASNTNVTGVSDLLALDKQIELIKKVVPNAKRVGMVYNPGEANSVVVVKQMQDLLPKAGMTLVEAAAPRTVDVASAARSLIGKVDVIYTNTDNNVVSAYESLVKVGNDAKIPLVASDTDSVKRGAIAALGINYRDLGVQTGKMVVRILKGEKPGAMSSETSSKLELYVNPGAAAKQGVTLSDALVKSAAQVIK
>NC_018828|1715779:1774980|1741062_1741857_+|WP_015039425.1|DBSCAN-SWA
MLSAKDLHITFNAGTPIETRALRGLSLDIPNGQFVTVIGSNGAGKSTFLNAISGDLPVDTGTIRINDADVTRQPVWERAGRVARVFQDPMAGTCEDLTIEENMALAHMRGARRGFSRAVKASMREGFRERLATLGLGLENRLADRIGLLSGGQRQAVSLLMAALQPSRILLLDEHTAALDPRTADFVLQLTARIVAESQLTTMMVTHSMRQALDVGERTVMLHQGQVVLDVSGDERKGMDVPDLLAMFERVRGEKLSDDALLLG
>NC_018828|1715779:1774980|1740170_1741061_+|WP_015039424.1|DBSCAN-SWA
MSLFSLLGALEIGLIFSLVALGGLISFRLLRFPDLTVDGSFPLGGAVAATLIAAGYDPFTSTIVATLAGAAAGLVTGWLNVRLRIMDLLASILMMIALYSVNLRIMGKPNVPLITEPTVFTLLQPQWLSDYVARPLILLVVVIIVKLALDWFLATQAGLAMRSTGSNGRMARAQGVNTGAMILAGMALSNALVALAGALFAQTQGGADISMGIGTIVIGLAAVIVGESILPSRRLVMATLAVILGAIVYRFFIALALNSDFIGLKAQDLNLVTAVLVTIALVIPMLKRRLVGRKGA
>NC_018828|1715779:1774980|1770217_1772269_+|WP_015039462.1|DBSCAN-SWA
MANIRTLQRSFSGGEISPEMFGRNDDAKYQSGLARCRNFITKPQGPAENRPGFAFVRAVKDSTKKVRLIPFTYSTTQTMVIEMGPGYFRFHTQGATLMSGGVPYEIANPYAEADLFDVHYVQSADVLTLVHPNYAPRELRRLGATNWQLTTLSFAASIAAPGAPSLSAAGHTSVKYTYYYVVTAVDSEGVSESAASASSSVGGNLFQTGATVTISWAAVTGASRYNVYKLQGGLYGYIGQTTGLSIVDDNISPDLGKTPPLYDSVFNGAGDYPGAVSYFEQRRCFAGTTNKPQNIWMTKSGTESNMSYSLPIRDDDRIAFRVAAREANTIRHIVPLTQLLLLTSSAEWRVTSVNSDAITPSTISVRPQSYVGSSNVQPVIINNTLIYGAARGGHVRELAYNWQASGFITGDLSLRAAHLFDTFDIVDMAYAKAPQPMVWFVSTSGRLLGLTYVPEQQVGAWHWHDTDGVFESCTVVAEGGEDALYCVIRRTINGASVRYVERMASRQFSDQADAFFVDCGATYSGVPADVISGLGHLEGKTVSILADGAVHPQRVVTGGSITLDIEASTVQIGLPIEADLQTLPLAVQLQDGSFGQGRFKNVNKVWLRVYRSSGIFVGPSVSELTEAKQRTTENYGAPPALKSEEIPLVLTPSWADSGQIFVRQSDPLPLTVVSLTAEVALGG
>NC_018828|1715779:1774980|1756931_1757147_+|WP_015039442.1|DBSCAN-SWA
MVNPIEPGVIPHEFQRDVIAAAIKSAAFALRQSREADPAKAARQVAEAAVVAWEVVNGLSRSASPSPRTAG
>NC_018828|1715779:1774980|1750161_1750344_-|WP_010926410.1|DBSCAN-SWA
MSRRLIAYLRATRLDLDLAGYAAMVAALAVATGLIGPTLDARSTLTACEGCGKTAVAAKE
>NC_018828|1715779:1774980|1769608_1770214_+|WP_015039461.1|DBSCAN-SWA
MASEVDICNLALAHLGDNATVASIDPPEGSAQAEHCARFYAIARDCLLEMHAWKFATRRVQLAKLTVPSWDWSFAYAEPTGALKLLGVLSATASNDDETQPYEAESDTNGTAIILTNQEDASLRFVARVTDTTKFSPLFVDALAWLLASYLAGPVLKGDAGAAMSKACLQSFLLAFSNAKVSDANQRKVRPEHTPAWIAGR
>NC_018828|1715779:1774980|1737269_1738259_+|WP_015039422.1|DBSCAN-SWA
MKYPILGAALIAATALIAATALGAAAPAQAAWPERPVTIIVPFPAGGGTDTFARPLAQQLGMQLGQSVVIDNKGGAGGTVGAAVASKAKPDGYTFFMGGAHHALAPSLYKNLSYDIQKDFVPVALLAQPPQVVVINTAKLPVKSLQEFIEYARKRPGDINFGTAGKGSTHHLAGELFAMQTGITLVDVPYQGAGPMLSALIGGQVDLAFDGLGSSAGHIRAGTIKPLAVAASQRSPSFPDVPTAAQAGVPNYEVSTWYALWAPAGTPQEAVDKMTAAVTKALNDPKIRETWAGNGSAIPNLTGPQFGAFVDSEVTRWAKVVKDSGVTLD
>NC_018828|1715779:1774980|1749171_1750158_-|WP_015039433.1|DBSCAN-SWA
MNNLAVITQDIYNARESFAAVLTDQSISFEKEAGFAIQVLQNNDYTLKVATGNRQSVINAVTNVAAIGISLNPAKRQAYLVPRDGRICLDISYMGLIDLAVATGSIRWAQAELVRSADTFALNGFDAPPTHVFNPFSKERGEIIGAYVVVKTADGDYLTTPMSRDEIDGIMNRSQSVKSGKSSPWKTDYGEMAKKTVVKRAYKYWPKNDRLSEAIHHLNTDGGEGLATTASAPVDPDLLPRLRKAVDAARDAAALEKVWKDGLAEVRATRDMAIYNAFKSAVAARGAVLRGEAVSIEPPPDDGKTIDEPPRDPSDDGFGRDDQGGIQE
>NC_018828|1715779:1774980|1747535_1748039_-|WP_015039430.1|DBSCAN-SWA
MRTDRELLELASLRSLLSYNPESGEFRWLKTNSNASVAGSVAGRSINSDGYKQIVIAGRFYKAHRLAWFYVHGEWPNQIDHINGIRTDNRLSNLRNVSAQHNTHNQRNPHKNNRSGFLGVVARPNGRYQAEIRVNGRKKFIGTFSTPEEASLAYVSAKREMHSGATL
>NC_018828|1715779:1774980|1720014_1720464_-|WP_164926495.1|DBSCAN-SWA
MATKAKAPAKKVTKTAAKTPAKTPAKAPAKKAPAKPAVKKTAAAVRPIKEALNKSQLIAYLVENTGVEAKSVKAVLAGLESSVLASVDKKGAGEFTLPGLFKVAVQKVPAKAKRFGKDPFTGEERWFPAKPASVKVKVRPLKKLKDAAQ
>NC_018828|1715779:1774980|1728749_1730012_+|WP_015039417.1|DBSCAN-SWA
MSKIEVKNIYKIFGPHPGKWLQAARDGISKEDLLAKSGHTLGLRDISLSIEEGSIYVIMGLSGSGKSTLIRHFNRLIEPSAGHILVDGVDVVSLNKRDLETFRQKKMSMVFQRFGLFPYRTVLDNAGYGLAVQGVARAEREQRARHWLDQVGLSGFENQYPHQLSGGMQQRVGLARALATDAEILLMDEAFSALDPLIRREMQDHLLQLQAKLNKTIVFITHDLDEALRLGNRIAILKDGELVQEGTPEDILLNPATEYVQSFLQDVNRTKVLNAAHAVNPPRLTLTMRSRPAHALDRMQALSYEYAPVLDGKRLAGVLMAAAAQQAVDEGARDVSRFVEDLASVPATAGLDQVLAQLVHSDQPVAVTGEGDEFIGMLSRKKVVELVTPVLAESDSADGQGDAADAASDGAGQAHERDAA
>NC_018828|1715779:1774980|1750720_1750930_-|WP_010926412.1|DBSCAN-SWA
MPGTGDTMETTYISDEQAVQVMAQLGGSFMKQLARLWMTADPLRRARLKEAFRDDFDRYRDMAARSDEA
>NC_018828|1715779:1774980|1742947_1744126_+|WP_003810332.1|DBSCAN-SWA
MSKRKARRGAGMPDYETVALVLQGGGALGAYQAGVYEGLHAAGIRPNWLAGISIGGINAAIIAGAPVDERVGRLRGFWEAICRPTGFAGLPWGDAWAALFANAPFGFGSNQSNGQLAAFNALTRGQPGFFEPRFPPPYLVQGGGAAATSFYDTTPLLQTLRDYVDFDLLNRGDVRVSLGAVNVRTGNFAYFDSRETVIRPEHVMASGALPPGFPAIEIDGEFYWDGGLVSNTPLTKVLAVHPMRDTLAFQVDLWPARGPLPTSLEEVAERQKDIQYSSRTRIVTDTFRRQLKLRRSLQRVLDRLPPQVRSSRELAQIRREACTPLVNVVNLIYEANQFERHSKDYEFNTESMREHWRFGLADIERTLAQPGVLDKPSPDESFVTHDIHRADA
>NC_018828|1715779:1774980|1745592_1746816_-|WP_164926497.1|DBSCAN-SWA
MTIRELKDGPRLQIAFSYRGEQCRELLPAGKVTKSYMEYAAGLRAEIRRKITDGTFSYRTYFPESPAAARMEPSPAAIPGAKLLLGALLDAQLALYEKQAANGSISASTLLGYAKAIKHYLRPRWGDTPVNELAPADLRAWIAGMGVTGKTVRNRLTPLRSVLDDAVNDELLDSNPLDRIALGKLIKQTATKSNYEVDPFDMDEVSALRQAARADELPLIQFWFEAGLRPGEIQAVEWASVDWVHGRVRIDDNIVTGMVEGKAAQVRKAPKTQAGIRDVDLSPLALAALKAQKAFTFLAGGRIWHDPRKNEPWASDAQIRKSLWQPLCKRAGVRYRNPYQMRHTYASTRLTAGANPWYIADQLGHTDVEMVFKIYGKFIPKNFQRAGAFTPVSHADQAADKTGTVSG
>NC_018828|1715779:1774980|1758026_1758818_+|WP_164926500.1|DBSCAN-SWA
MSYEVMKACRPLQMPSSPKAVLMALADYADEAGSAWPSIPTLCEYTCLSERTVHAAIKWLEQAKVVVADRANGRHTTYVVDANSFQQPPQQLRPRSSCTPANPAVTPAVAAVVPPQIPQSPPQQLRSNNQEQPREQPGTTNKRVRKPKDSGFDAMKVDLPDWLPAESWERWVRHRVQLKKPITEETARQQIEDLGTFRGQGHQPDDVIRHCIGKSWQGLFPPKQGFGPRPAPAVSEADRRKQEFLRLAGHGGNDSGTIDMEQA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010926800.1|1715779_1718437_-|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	2.5e-173	39.0
WP_015039414.1|1718514_1719384_-	MFS transporter	NA	NA	NA	NA
WP_164926495.1|1720014_1720464_-	DNA-binding protein	NA	NA	NA	NA
WP_015039415.1|1720805_1722701_+	STAS domain-containing protein	A0A2H4J153	uncultured_Caudovirales_phage	4.3e-18	26.3
WP_003810296.1|1722814_1722982_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_003810297.1|1723045_1723282_-	50S ribosomal protein L28	NA	NA	NA	NA
WP_164926688.1|1723651_1724797_-	multidrug effflux MFS transporter	NA	NA	NA	NA
WP_033447541.1|1725013_1726270_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_003810304.1|1726721_1727723_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003810306.1|1727895_1728753_+	proline/glycine betaine ABC transporter permease	NA	NA	NA	NA
WP_015039417.1|1728749_1730012_+	glycine betaine/L-proline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.0e-28	36.6
WP_010926797.1|1730112_1730487_+	4-oxalocrotonate tautomerase	NA	NA	NA	NA
WP_164926496.1|1730559_1731741_+	acetyl-CoA C-acyltransferase family protein	NA	NA	NA	NA
WP_010930714.1|1731823_1732594_+	spermidine synthase	NA	NA	NA	NA
WP_015039419.1|1732707_1733472_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_010928183.1|1733422_1734724_+	malonyl-CoA decarboxylase	NA	NA	NA	NA
WP_165446305.1|1734732_1735527_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_015039421.1|1735532_1737074_+	malonyl-CoA synthase	A0A2H4PQM9	Staphylococcus_phage	1.0e-25	25.9
WP_015039422.1|1737269_1738259_+	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_003810321.1|1738415_1738928_+	superoxide dismutase family protein	Q9MC02	Salmonella_phage	1.4e-43	52.3
WP_015039423.1|1739086_1740061_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_015039424.1|1740170_1741061_+	ABC transporter permease	NA	NA	NA	NA
WP_015039425.1|1741062_1741857_+	ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	3.9e-05	25.7
WP_015039426.1|1741882_1742236_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_015039427.1|1742346_1742937_+	DUF4136 domain-containing protein	NA	NA	NA	NA
WP_003810332.1|1742947_1744126_+	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_015038907.1|1744161_1745382_-|transposase	ISL3-like element IS1001 family transposase	A4PE56	Ralstonia_virus	5.1e-198	81.3
WP_164926497.1|1745592_1746816_-	DUF3596 domain-containing protein	A0A1W6JTA0	Pseudomonas_phage	1.8e-62	37.7
WP_164926498.1|1746812_1747067_-	excisionase	NA	NA	NA	NA
WP_015039429.1|1747179_1747539_-	hypothetical protein	W6MWX0	Pseudomonas_phage	1.6e-11	44.3
WP_015039430.1|1747535_1748039_-	hypothetical protein	A0A1B1W266	Salmonella_phage	1.5e-26	45.8
WP_164926388.1|1748028_1748409_-	hypothetical protein	NA	NA	NA	NA
WP_015039432.1|1748527_1749175_-	YqaJ viral recombinase family protein	A0A0U2BXF3	Paracoccus_phage	8.8e-32	41.4
WP_015039433.1|1749171_1750158_-	phage-related DNA recombination protein	H9C0R8	Aeromonas_phage	4.0e-68	57.8
WP_010926410.1|1750161_1750344_-	hypothetical protein	NA	NA	NA	NA
WP_010926411.1|1750340_1750718_-	hypothetical protein	NA	NA	NA	NA
WP_010926412.1|1750720_1750930_-	hypothetical protein	NA	NA	NA	NA
WP_015039435.1|1750949_1751849_-	hypothetical protein	Q3HQX1	Burkholderia_phage	9.4e-40	68.1
WP_015039436.1|1751887_1752772_-	pentapeptide repeat-containing protein	A0A2P0VPH6	Ralstonia_phage	1.5e-10	45.7
WP_080700710.1|1753706_1753946_+	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_015039439.1|1754069_1754564_-	hypothetical protein	NA	NA	NA	NA
WP_033448667.1|1754580_1755255_-	hypothetical protein	NA	NA	NA	NA
WP_015039442.1|1756931_1757147_+	hypothetical protein	NA	NA	NA	NA
WP_164926499.1|1757106_1757289_-	hypothetical protein	NA	NA	NA	NA
WP_015039444.1|1757655_1758030_+	hypothetical protein	NA	NA	NA	NA
WP_164926500.1|1758026_1758818_+	helix-turn-helix domain-containing protein	A0A1B0YZZ0	Pseudomonas_phage	9.2e-15	45.4
WP_015039446.1|1758817_1759573_+	hypothetical protein	U6C6D0	Ralstonia_phage	1.0e-26	38.0
WP_015039447.1|1759569_1760046_+	phage protein	NA	NA	NA	NA
WP_165446306.1|1760927_1761098_+	hypothetical protein	Q775A6	Bordetella_phage	1.8e-21	98.2
WP_164926501.1|1761285_1761528_+	hypothetical protein	Q775B7	Bordetella_phage	1.2e-10	45.5
WP_015039451.1|1761534_1762026_+|terminase	phage terminase small subunit	A0A0B5A1T2	Achromobacter_phage	6.3e-14	47.2
WP_015039452.1|1762022_1763618_+|terminase	phage terminase large subunit	Q775B9	Bordetella_phage	1.7e-310	97.4
WP_164926502.1|1763610_1763754_-	hypothetical protein	NA	NA	NA	NA
WP_164926503.1|1763917_1764379_+	GNAT family N-acetyltransferase	Q775C0	Bordetella_phage	1.6e-35	53.4
WP_015039454.1|1764375_1764837_+	phage protein	Q775C1	Bordetella_phage	2.8e-40	58.8
WP_164926504.1|1764839_1765154_+	hypothetical protein	Q775C2	Bordetella_phage	4.7e-07	79.5
WP_015039455.1|1765155_1766823_+|head,tail	phage head-tail connector protein	T1S9Z7	Salmonella_phage	1.2e-141	47.3
WP_015039456.1|1766866_1767214_+|protease	phage endoprotease	Q775C5	Bordetella_phage	2.4e-52	87.0
WP_164926505.1|1767170_1767860_+|protease	protease	Q775C6	Bordetella_phage	2.8e-108	98.7
WP_015039458.1|1767873_1768869_+	phage protein	Q775C7	Bordetella_phage	1.3e-186	98.5
WP_015039459.1|1768924_1769347_+	phage protein	Q775C8	Bordetella_phage	2.2e-60	87.9
WP_164926506.1|1769359_1769542_+	hypothetical protein	Q775C9	Bordetella_phage	1.6e-10	57.1
WP_015039461.1|1769608_1770214_+	phage protein	Q775D0	Bordetella_phage	1.4e-60	59.0
WP_015039462.1|1770217_1772269_+	phage protein	Q775D1	Bordetella_phage	0.0e+00	77.3
WP_164926507.1|1772328_1772853_+	hypothetical protein	Q775D2	Bordetella_phage	3.1e-27	39.6
WP_015039464.1|1772856_1774980_+	transglycosylase SLT domain-containing protein	Q775D3	Bordetella_phage	0.0e+00	91.5

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_018828|1783207:1787019|DBSCAN-SWA
GATGGAACCCATCGAGGAAGCGACAAAGTGCTACGACCAAATGCTCATTGTGGAACGGTACGAAAGGGTTATTTCGTACCTGTATCCCATTGCGCAAAGCATCCCGAGCAAGCACGGCGTCGCGCGGGAAATGTTCTTGAAGTGCCTGCTCGGGCAGGTCGAATTATTCATCGTGGCGGGCAAATCCAATCAGGTCAGCAAGCTGTACGCGGCGCACGCCGGGCTTGCCATGCTGCGGTTTTGGTTGCGCTTTCTCGCGGGCATTCAGAAACCGCACGCGATGACGCCGCATCAGGTCGAGACAGCACAAGTGCTCATCGCCGAAGTGGGGCGCATCCTTGGTTCCTGGATTGGCCGCGTGAATCGCAAAGGGCAGGCTGGGAAATAACGCTGCTGCGCAAGTCCTCGGTCAAGCGGGCGAAGCGCAAGGTCGCCAATTTCATCAAGCACGGCGAGGATGAATCTCTGCAGCGGTTTCTCGCCTCGTGGTCGGGTCATGCGCAATGGGCCGACACCCACAACCTTTTCACCTGGATGGAGGAACAATATGGCATCGCCTGTCATTAACACCCGCGAGGACTTGGACGCCCTCGCCGGCACGCCGGCCCACGGCGAATTTCTCGACTACCTGCGCGGCAGCATCACGCGCAAACAGGACGCGCAGACCTACCCCGATGGGTACGGCACGCCCGACTACGAAGGGCCGACCCTCGACCCCGTGTGGCAGGACGTGGAGGACTTGAGCACCATCGAGCGGTTCGGCTTCACCAAGGCCGAACTGCTGGGCGGCGAATAAGGGGGCGCCATGTCCGACCAGCACTGCGATACCCCGGCCTGCCAGGAGGCCGCCGACCGCGCTGTCAAGAAGGTGTTTGCCATCTTGGGCGTGGATGTGGACGTGCCGGAACAGGTTGAAGAATTCCGCGAGGACTTGCGCTTCGGTCGCCGGATGCGCAAGGCCGCCGACCACGGCTTTCTCGCGCTTGTGGGCCTGGTGGCCGTGGCCCTGGGTGCGGCGGTGTGGGCGGGCATCACCTCGAAACTTGGGGGCCACTGACATGAACTTCGACACCGCTTTCGACCGCCTCATCGGCCATGAGGGCGGTTATTCCAACAACCCGGCCGACCCCGGCGGCGAGACTATGTGGGGCGTGACCGCCGCCGTAGCGCGGGCCAACGGCTACACCGGGCCGATGCGCGACATGCCGCGTGATACGGCCAAGGCGATCTACCGCGCACGCTATTGGACGCCGATTCGCGGCGACATGCTGCCGGCGGCCGTGGCCTTCCAAGTGTTCGACGCCGCGGTGAACCACGGCACCGGCCAGGCGGCCAAGTGGCTGCAAGCTGCCGTGGGCACCGTGCAGGACGGACAGATCGGCCCCCTGACACTCAATGCCGCGGCCGGGATGAACCCCACCATGCTGGCCCTGCTGTTCAACTCGGCTCGCATGAGGTTCTACACCAACCTGCCCACCTGGCCGACGTTCGGCAAGGGCTGGGCGCGGCGCGTCGCCGCAAACCTGAAATACGCTGCGCAGGACATCTAAATGGACTGGAAAGACCTGGCCGGCGTTGTCGGCAAAGCCGCCCCTATCCTGGGCGGTATCTTGGGCGGCCCGGCCGGCGCCGCCGTAGGCGGCCTGGTGGCTACGGCCTTGGGCACCGACTCGACGCCGGACGCCGTGTCCACGGCGCTGCTGGCCGACCCGCAGGCGGCCATCAAACTCAAGGAACTGGAAACCAACTCGCGCGTGCAGCTACAGCAACTCGCGGTGACGGCCGAACAGAACCGCCTGCAAGCCGCCGCGGCGCAGTATGCTGCCGAGGCATCCGACCGCGACAGCGCCCGCAAGCTGGCCGCGCAGCAGCCCAACGACAAGGTGCGGCCGACGATCACCGCCGTGCTGCTGGTGGGCGCCCTGGGCATCGTCTATTTCGTGTTCTCGGGCCTGGCGGACGGCCTCCTTCGCGACGCCACCGCCAGCCTGACGGTGGGGACGGTCATCGGTTACTGGTTCAACGAGTTGAAGCAGACCCTCGCGTTCTGGTTCGGCACCACCGGGGAAACCCAGCGCGCCAATGCTGAGGTGCGCCAGTTCGCCGTGTCGCCCGGCAGCGTGACGGTGCCCGGCGATACCGGGGCGCATCCGCCTGCGGGCAAGCCTGGCACCACGCCGTAGCTTGGGACAAATCTTGGGACAAATGCGGGGGGACGCTGGGGCAAAGGAACACGCAAAACCCTGCAAAATCAAAGGCAAAAGTCCCCGCAATTCCCCTGTAATCCCCTATAGTTTGGGTTCGAGTCCCATCAGCCACCCCACACGAATTCGTTGGAAAACAGGCACTTAGGCGCAAGCCGAGGTGCCTTTTTTCTTGGGCGAACGGTGGCAATGTCTGGGCCTTGTGGCATGGGTCATCAGGCGCGGCTTCGCGAATGGCTAGCGCAGGCCACCATTGCCGCACTCGAAGCGGTTCGAGAGGAGGGCAGGCGGCGCACTGCCGCTGTGGAGAAAGCTCGTGATGACGCTCAAGAATTGGCCGCCGCTGCGGCCGCTAATGCTGTTGGCGCTCGTGCTGAGCGTGACCGGCTGCGCACCCACGCAAACGCGCTGGCTCGCGCCGCAGTCGCCCGAGATCCCGATGCTGCCGATGGAAGCCCGACAGGGGCCAGCGCCGTCGATCTGCTTGCCTACATGCTCAGCAGGGTTAGCGGCCGAGCTGAAGCGCTTGCAGGAGTTGCGGACCGTGCCCGCATCGCCGGATTGACCTGCGAACGCGCCTACGAGGCGGTGCGCGGCAACGTGCGCCCTTAGCCCTTGCGAGGCTGGGCCGGCGCGTTCAGCATCTCGGCCACGTCTGCGTCGCGCTCGAGCACACAGGGCTCGACCACCAGCTGAGCCATGTATTCGTCGTAGCAGTTGGCGAGGACGCCGACAGGCCGGTGGAATTCGCCCGAGAGCTGATAGGCGCGCAGCATCATCGAGCGCAGGCGCTTGACCTCCCATAGGAGGGTCAGCACGTCGGGGTTCCAGGGCTGGCGCTCGCGGATGGCGCGCAGCTGGGCGTGGGTGAGGGGAGATCGGAACGGCATAGCAAAATCACTGTGTGAATAAACAGTATATGCCGGCCGCCGGATCCTTAAATGGGGTCGATTGCGTCGGGGAGCTGGTACTTGCTGGATCCGACTTCCTGCCGGACCGGGTGCCAGGAAAAGGCCGTCTCGGGCAGGCCGGCGCGCAGGATCTCCATCGCCCTGGCCACCGGCGTCGCCGGGTCCACCCATTCCCTGGCCAGCTCAGGGGGCAGCGCCACCGGGCGCCGGTCGTGCACGTCTACCATGCCGCCCAGCGAGTCGTTTGTGACGATGGCAAGGCCGTGGGCCTCGTCCAGCTCGGCACCGCGGCGCCACGCGCTCAGACCCGCGAAGAGTAGCGGGGCGTCGCCATGGATGTAGTAGGGCTGCTTGGCTGGCTTCGGGCCGCTATCGAGGGCCTTCCATTCGTACCAGCCATCGGCCGGAACTAGGATGCGGCCGACCCCAATCATCAGCTTCCAGGGCCAGCCGTGGCGCTCGATCGTCTCCAGCTTGGCATTGACCATGAAGAACCGGGAGCCGTGCGGCTTGTAGCCCCAGGGCAGTCTGGCCAGCGCCTCGGCCTGGTCGACAAGTCGGTGCATGGTCAGGGGCCTGGTGCCTGGCGGGATGTTGTACCGCGGCCCGGCCACGTCATCGAAGACCAGCCGGGCATTCGGCCACAGGATCTCGACGTAGTCTTCGGGTGCTGACTTCTGGGCAATGCGGCCGCACAT

Protein sequences of DBSCAN-SWA_2

>NC_018828|1783207:1787019|1784011_1784263_+|WP_015973918.1|DBSCAN-SWA
MSDQHCDTPACQEAADRAVKKVFAILGVDVDVPEQVEEFREDLRFGRRMRKAADHGFLALVGLVAVALGAAVWAGITSKLGGH
>NC_018828|1783207:1787019|1783207_1783594_+|WP_015039467.1|DBSCAN-SWA
MEPIEEATKCYDQMLIVERYERVISYLYPIAQSIPSKHGVAREMFLKCLLGQVELFIVAGKSNQVSKLYAAHAGLAMLRFWLRFLAGIQKPHAMTPHQVETAQVLIAEVGRILGSWIGRVNRKGQAGK
>NC_018828|1783207:1787019|1784264_1784756_+|WP_015039468.1|DBSCAN-SWA
MNFDTAFDRLIGHEGGYSNNPADPGGETMWGVTAAVARANGYTGPMRDMPRDTAKAIYRARYWTPIRGDMLPAAVAFQVFDAAVNHGTGQAAKWLQAAVGTVQDGQIGPLTLNAAAGMNPTMLALLFNSARMRFYTNLPTWPTFGKGWARRVAANLKYAAQDI
>NC_018828|1783207:1787019|1786018_1786300_-|WP_015039471.1|DBSCAN-SWA
MPFRSPLTHAQLRAIRERQPWNPDVLTLLWEVKRLRSMMLRAYQLSGEFHRPVGVLANCYDEYMAQLVVEPCVLERDADVAEMLNAPAQPRKG
>NC_018828|1783207:1787019|1784756_1785389_+|WP_164926508.1|DBSCAN-SWA
MDWKDLAGVVGKAAPILGGILGGPAGAAVGGLVATALGTDSTPDAVSTALLADPQAAIKLKELETNSRVQLQQLAVTAEQNRLQAAAAQYAAEASDRDSARKLAAQQPNDKVRPTITAVLLVGALGIVYFVFSGLADGLLRDATASLTVGTVIGYWFNELKQTLAFWFGTTGETQRANAEVRQFAVSPGSVTVPGDTGAHPPAGKPGTTP
>NC_018828|1783207:1787019|1786347_1787019_-|WP_015039472.1|DBSCAN-SWA
MCGRIAQKSAPEDYVEILWPNARLVFDDVAGPRYNIPPGTRPLTMHRLVDQAEALARLPWGYKPHGSRFFMVNAKLETIERHGWPWKLMIGVGRILVPADGWYEWKALDSGPKPAKQPYYIHGDAPLLFAGLSAWRRGAELDEAHGLAIVTNDSLGGMVDVHDRRPVALPPELAREWVDPATPVARAMEILRAGLPETAFSWHPVRQEVGSSKYQLPDAIDPI
>NC_018828|1783207:1787019|1783753_1784002_+|WP_150556910.1|DBSCAN-SWA
MASPVINTREDLDALAGTPAHGEFLDYLRGSITRKQDAQTYPDGYGTPDYEGPTLDPVWQDVEDLSTIERFGFTKAELLGGE

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015039467.1|1783207_1783594_+	diversity-generating retroelement bAvd family protein	Q775D7	Bordetella_phage	8.0e-65	97.7
WP_150556910.1|1783753_1784002_+	hypothetical protein	Q775D9	Bordetella_phage	6.1e-42	98.8
WP_015973918.1|1784011_1784263_+	hypothetical protein	Q775E0	Bordetella_phage	4.4e-40	100.0
WP_015039468.1|1784264_1784756_+	N-acetylmuramidase	Q775E1	Bordetella_phage	1.3e-88	95.7
WP_164926508.1|1784756_1785389_+	hypothetical protein	Q775E2	Bordetella_phage	7.9e-94	99.0
WP_015039471.1|1786018_1786300_-	hypothetical protein	NA	NA	NA	NA
WP_015039472.1|1786347_1787019_-	SOS response-associated peptidase	Q5QF62	Pseudomonas_virus	6.1e-36	40.3

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NC_018828|2253901:2260898|DBSCAN-SWA
GATGGGGACGTACCGCAAACGCGGGGACACATGGCGGGCTGAAATAAATAAGGCCGGCGTCCGAGAGAGCAAGACGTTTCCCACGAAGCGCGAGGCCCAGGAGTGGGCCGCGGCCCGGGAAACGGAGCTGGCGACCATCGCCGTGGGGGGAATCACCCCGAAATCTGTTGCGCAAGTGCTACAGCGGTACTGCGACGAGATATCCCCTCGGAACAAGGGGCACCGCTGGGAGCGGGTCCGGATCGCGCGCTTCTTGAAAGAAGAGGCGGATCTTTGCGCCAAGCTCATCCACACCATCAGTACCGCGGACCTCGGCGCATGGCGTGATCGCCGGCTGGCGCAGGTGCAGCCCGTCTCGGTACGGCGTGATATTGCCCTCCTGCGGGCCGCCTGGGGTTACGCCAGGCGCGAATGGAGGAACCTGAAGGATGACCCCTGGCTGGACCTGACGATGCCGCCAGAGGGCCGTCATCGTGAGCGAATTTACACCCAGGACGAAGTAGACCGCCTCGTATTGGCGCTCGGCTGGGAAGAAGGGCAGAAGGTGGTGACCGCCCGCCAGCAGACAGCCGTTTGTTTCCTGCTATCCCTCGAAACCGCCATGCGGTCAGGCGAGCTGCTGTCGCTGGAGCACTCGCAGGTAGACCTGAAAAAGCGGGTAGCGCAACTGGACCAGACGAAGAATGGTGACCGCCGGGCGGTGCCTCTGTCCTCGCGGGCCGTTGCGCTGTTCAAGAGCCTGGCCGGCCTGGACGATGCCAAGGTCTTCACGATCACGCCGGCGCTGCGTGACGTGTACTTCCGGCAGGGCAAGGCCATCGCTGAAGTTGACGGGGCGACGTTTCACGACGCCCGCGCTACAGCACTCACGAGGCTATCGAAAAAGCTGTCCATCCTGGAGCTGGCCAGGATGGTCGGGCACCGGGACCCGCGCAGCCTCATGATCTATTACCGCGAGAGCGCCGCGGATATCGCCAAGAAACTGGATTAAGCCGCGCGCCTGCCATCGGGAGCCTGGCGTCGGCCATCAATCCAGTCCTCGACCTCGCTGTATTTCCACCGGCGCGCGCCGCCGAAAATGAAGGGGCGGGGGAAGTCCTTCCGCTTGGTCAGCCTGTCGCGCACATGCGCTGGATTCAGCTGCAGGAGGCTGGCGATTTCGGTGTGTGTGATAAAGCGGTCTTCCATCTATTCCTCCCGTTCTTCCTTTTCGATTTCTCGGCTCAGCCAGCGGTGCAGGGCCAGGGCGAGCGCCACGACGGCGCCCACGGCGATGCCCAGCAGGGCGAGGTAGGGCAGGTCAGGCATGGGCGGCCTCCTGCATCTTGGCGCCGATCTCGGCAGCGGCACGGACGATGGCGCGGCGGGTGGCGGCCTCAATCCCGCCGTACTTGTGGGCCGCACATCCAAACCAGGTATCGCCGGGGCGCCGTGCAGAGCCACCATAGTCATCGACATGGACCCACAGGCGCAGCTTCACAGCCAGCCGCAGCGCATCGCCGTCGTCGGTGAGCGGGTTCCATTCGATGCCCGCCACCTTCCCGTGTGGGTCGGCCTTGGCCGGCCGCGTGAACAGCATGTGCGCCTGGAAGCCGGTGCCGGGCCACACTTCGATGCCGGCCGCTTTTGCAGATAAGATTAATAGTTCCAGATCAGTCATAGTGTTGCTCCCGAGTGCATTTCACGCTTCGCCGATACATACGCTAGGCTGGCTTCTTCGGGCGTGCTGAAGGTGCCAATAAATTTCTTTCGGCCATTAACGCGAATCTCCGCTTGATAGCGTCCGTTCGGACGCGCAACCACACCAAGAAAACCAGAACGATTGTTCTTATGAGGGTTCCGCTGATTGTGTGTGTTGTGCTGAGCACTTACGTTTCGCAGATTAGATAGTCTGTTGTCAGTGCGAATCCCGTTAATGTGGTCGATTTGGTTTGGCCACTCTCCATGAACGTAAAACCATGCCAACCTGTGAGCCTTATAAAATCGTCCTGCGATGACAATCTGCTTGTAACCATCGCTATTTATTGAGCGCCCTGCAACGGACCCAGCCACCGAAGCATTGCTGTTTGTCTTCAGCCATCTAAACTCGCCTGACTCCGGGTTGTAAGACAACAGGCTTCGTAGGCTAGCCAGCTCCAACAGTTCGCGGTCAGTTCGCATTGCCGTCCCCCTCCTTGCGCGCGACCAGGGAAAACGAGTTGTCCGCGAACGGCATGGCGCGGAAATCCATGTTCAGGTCGGACTTGCCGCCTATGCCGTGGTGAACGGTGACGGTCGCGCCGACGACTTTTTCAGATAGCGCGACCTTGTTCTGCATGTTGGGAAATTTCAGGCACGGCAGATAGCCAGGGTCGTCAAGGCGGGGGTCTGCGTTGTCGGCCATATCACCTTCGTCTTGCCGCGGCCGGCGGTAGAGGGACGATTTCAAATCCGGACTGAACTCCGACAGCACATCGTTGCTCGTGCGGTAGGTGAACTGCAGAGTGGCGGACGGTTGGTCGTTTTTCTTGGTGTTGGAGTCGAAGTGCATGCGGCACTCTTGTTGGTGGATGCTGAACATGGGGCAGGGCACCAAGTGGTGCTACGTGGGTAATAGGGCGGGCGGCGCCTGGGGATTCCTCCGTTGGTGGCGGCGCCGCCCAGGGAGATCAGGCGGCCAAGCGCTTCAACTGGGCGACCAGCTCGTCGCGCTCGGCCAGAAACTGGAGAACGGCCTTTTCGTGGTCGGCCAGCTCTTTGGCGGTTGGGGTGAAGCGGCAGACGAACAGCTGCAGCTCTTGCGGGAACCGTGGATCGAACGACACGAAGTCGGCGAACTCCGCACCGGTGACCCAGACGTTGTGCAGGCACTGCGGGCGATATTGGTCCGGCAGCGTGCCCGCTTCCAGATAGCGGATGTGCGTGGTGCTTTTCGGGCACTTCGTCTCGAGCACGCCGCGCCGGCCGTCTTCCACGAACAGGCCGTCAACGCTGCATCCGGCCGCCACGTCGGGCAGGTACATGAAGCCGCTTTCGATGGTGACATTGCCGGACGCTTCTTCGTAGGCCATGCGGGCGAACGGCTCCTGATCGATGCCCCACTGCATTTCCTTGCTGGTGTAATCGCTGCCTTGGGGCATGCCCGTCAGTACTTCGATGGCCAGCTCGAACTTGTAGTCGGCGCGCTTGGTCGACCATTCCTTCTTGGCCGTCATCGCCAGCATGTCGGCGGCGCGCGACCCGGTGACGCGGCCGCAGCGGTCCAGCAGCCAGCCGTCGCTGCCCTGCTCATGGGGGGAGAGGATGTAGCGGTTCATTCCTGGATACCTCCTTGGTCATCGCGGCCGAAGCCGTCGTCGGACGGGTCGCGGGGCGGCTCGTCGATGGTCTTGCCGTCATCTGGCGGGGGTTCGATGGATACCGCCTCGCCGCGCAGCACGGCGCCTCGCGCCGCCACCGCGGACTTGAAGGCGTTGTAGATGGCCATGTCCCGCGTGGCGCGCACCTCGGCCAAGCCGTCTTTCCAGACCTTCTCCAGGGCGGCGGCATCCCGGGCCGCATCCACGGCCTTGCGCAGGCGCGGCAGCAGGTCGGGATCGACCGGCGCGCTGGCGGTGGTGGCCAGGCCTTCGCCGCCGTCTGTGTTCAGGTGGTGGATCGCCTCCGACAGGCGGTCGTTCTTCGGCCAGTATTTGTAGGCGCGCTTCACCACCGTCTTTTTGGCCATCTCGCCGTAGTCGGTCTTCCAGGGCGACGACTTTCCGGACTTCACCGACTGGGACCGGTTCATGATCCCGTCGATTTCGTCCCGGCTCATTGGCGTGGTCAGGTAGTCGCCGTCGGCGGTCTTGACCACCACATAGGCCCCGATGATTTCGCCCCGTTCTTTGCTGAAGGGATTGAAGACGTGCGTGGGCGGGGCATCGAAGCCATTCAGGGCGAACGTGTCGGCGGAACGCACCAGCTCGGCCTGGGCCCAGCGGATGGAGCCGGTAGCTACGGCCAGGTCGATTAGGCCCATGTAGCTGATGTCCAGGCAGATCCGGCCGTCGCGCGGCACCAGGTACGCCTGGCGCTTCGCGGGGTTCAGGCTGATGCCAATCGCGGCCACGTTCGTCACCGCGTTGATCACAGACTGGCGGTTGCCCGTCGCGACCTTCAGGGTGTAGTCATTGTTCTGCAGCACCTGGATGGCGAAGCCCGCTTCCTTCTCGAAGCTGATGCTCTGATCGGTCAGCACGGCCGCGAAGGACTCGCGGGCGTTGTAAATGTCCTGGGTGATGACGGCGAGGTTGTTCAAGGGTTATTCCTTCGCGGCGACTGCGGTCTTGCCGCAGCCTTCGCAGGCGGTGAGGGTGGATCGGGCGTCGAGGGTCGGGCCGATCAGGCCGGTGGCTACCGCCAGCGCGGCGACCATGGCGGCGTATCCGGCCAGGTCCAGGTCAAGGCGCGTGGCGCGCAGGTAGGCGATGAGGCGGCGGCTCATTGCCGGCTCCCGAAGGTGACGCGCTGGCCGTCTTCGGTGAGCTCGACCAGCGTGTCCAGCAGTCGGGCGCGGGCCAGCTTGGTCCACTCGACAAACAGCGTGCCGACCGACACCGCGGACTCTCCGCGCGCCGCGGCACGGACCAGCAGCGAGAACGCCGCTTCGGATTGCGCATCGCCGATCGTGGCCGCGTACAGCGCTTCGGCGACCAGCTCCGGATCGCCATAGGGCCAGCGCACGCAGCGCTGCGCCACCAGGGCGTAATGCAGGTCGGCATCGAGGTCGCGCCGCAGCTCGGCCAGCCGCTCGGCGTCGGTCAGCGGGCGCACGACCGCAGCCGTGCCGCACTCGGTGGGGTAGGTGAGGGGAAGCATGGTCAGGCCTCGTCCGACCGTGCAGCCATGTCGCGGTAACGGTCGAAGTCGTCGCGGAACGCCTCTTTCAGGCGCGCGCGCCGCAGCGGGTCGGCCGTCATCCAAAGCCGGGCAAGCTGCTTCATGAACGAACCGCCGAGCTGGGCCATTACCTGCACCGCCTGCTCATCGCTGATGTAAGTGGTTTCCATGGTGTCTCCTGTCCCCGGCACCCGGGGCGGGTGGGGAAGGTCAAGTGGTCTGCTGCCAGGGCGCACGGCCCTCGCACATGGCAATGAACATCTCTTTTTGAGCGTCCCTGGCAGCGCCCAGGGCAGCGGCCCTGGCAGCGGCCCTGGCAGCGTCCCAGGCAGCGTCCCAGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGGCCCTGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGGCCCTGGCATCGGCACTGGCAGCGGCCCTGGCAGCGTCCCAGGCAGCGTCCCAGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGTACCAGGCAGCGTCCCAGGCAGCGTCCCAGGCAGCGGCCCAGGCAGCGTCCCAGGCAGCGGCACTGGCAGCGGCCCTGGCAGCGTCCCAGGCAGCGTCCCAGGCAGCGGCACTGGCATCGGCACTGGCAGCGGCCCTGGCAGCGGCACTGGCAGCGTCCCGCTCTTCCTCGGTGGCTTCGCCGTTGGCGAAACGCTCGGCCACGTCCAGCGCGTCCTTGCTTCGCTGATCCGTCATCAGATGTTCAACTTGGCGAGCGCACCAGACGGCGAACAGGCGCGCATGGCGATCAACACCGGGCACGCAGCGAAGCGCCCACAGCGCGTCATCCAGGCCGTTGCTTGCGATGATGGCCGTCAACGCGACCGGCTCGGCATGTGAAAACTTGATATAGCTTTCGCGCGCGCTGTCATCGTCGGAAAACTCACGGCCCTGAACGGCACGGACGACCTTGTTGTAGCCCTCGAAACATGCACCATCGCGGCGCAGATCAGCGAGCGTGACTTCGAATTTGAGGGTGGCCTTGGTATCGGACACAGTTATCTCCTGGCCCCTACCGGGGCGGGTGGGCAAGGTCAGGCCACGGGCTTGGTCTGCTGCGCGGCCTGTTCGCGCAGGTCGGCCATGGCGAGCTCGTTGCTGGCGAAGAAGTGCGGCGCACGGCCAACGGATGCCATGTAGATCATCCGGCCGGCATACTGCGGCCCGTGCTCACGTTCGAGCGCATAGCCAGCTTCGCCCGCCAGATGGACTGCCCAGCCAGCGCGGCAATGGGTCGTTTCGCAGGTGTGCCATGCCCCCATTTCTAGGCCGCCTCTTCCGTTCTCGATGGCGGAAAGGATCTTCGCGTCCAGCGCTTCAACTACGGGCACGGTGGGATTGAGTTCGCGGAAGCGCGCGGCGCGCGCTGCATTGCGTTCGGCTGCGGGGCGCGTGTCGCGCTGATATGGTTCGACCGGGCTGGTAGCTTCGGTGCCAACCGGCAGGTTTCTCGCGCCGGCCAGGTTCGCGCGGGCCAGGTACGCGCCGGCCAGGTTCGCGCCGGCCAGGTTCGCGCGGGCCAGGTCCGCGCCGGCCAGGTCCGCGCCGGCCAGGTTCGCGCAGGCCAGGTTCGCGCGGGCCAGGTCCGCGTCGGCCAGGTACGCGTCGGCCAGGTACGCGTCGGCCAGGTACGCGCGGGCCAGGTACGCGTCGGCCAGGTTCGCGCCGGCCAGGTTCGCGCGGGCCAGGTTCGCGCGGGCCAGGTTCGCGCCGGCCAGGTCCGCGTCGGCCAGGTACGCGTCGGCCAGGTTCGCGCCGGCCAGGTTCGCGCGGGCCAGGTTCGCGCGGGCCAGGTTCGCGCGGGCCAGGTTCGCGCCGGCCAGGTCCGCGTCGGCCAGGTACGCGTCGGCCAGGTTCGCGCCGGCCAGGTTCGCGCCGGCCAGGTCCGCGCGGGCCAGGTTCGCGCCGGATTTCACGGCCTGCTCCAGCGCCACACGTGCAACCATGCCGCTCTCGGTTTCATCAGGCACATCAGCCGTGAAGAGCACGGCGCCGGTCCAGCGGTTCTTGATCTCGAAATTCAC

Protein sequences of DBSCAN-SWA_3

>NC_018828|2253901:2260898|2255200_2255560_-|WP_015039429.1|DBSCAN-SWA
MTDLELLILSAKAAGIEVWPGTGFQAHMLFTRPAKADPHGKVAGIEWNPLTDDGDALRLAVKLRLWVHVDDYGGSARRPGDTWFGCAAHKYGGIEAATRRAIVRAAAEIGAKMQEAAHA
>NC_018828|2253901:2260898|2254887_2255088_-|WP_010926403.1|DBSCAN-SWA
MEDRFITHTEIASLLQLNPAHVRDRLTKRKDFPRPFIFGGARRWKYSEVEDWIDGRRQAPDGRRAA
>NC_018828|2253901:2260898|2258970_2259870_-|WP_015039653.1|DBSCAN-SWA
MSDTKATLKFEVTLADLRRDGACFEGYNKVVRAVQGREFSDDDSARESYIKFSHAEPVALTAIIASNGLDDALWALRCVPGVDRHARLFAVWCARQVEHLMTDQRSKDALDVAERFANGEATEEERDAASAAARAAASADASAAAWDAAWDAARAAASAAAWDAAWAAAWDAAWDAAWYAARAAASAAARAAASAAARAAARAAASAAARAAAWDAAWDAARAAASADARAAASAAARAAARAAARAAASAAARAAAWDAAWDAARAAARAAALGAARDAQKEMFIAMCEGRAPWQQTT
>NC_018828|2253901:2260898|2255556_2256060_-|WP_015039430.1|DBSCAN-SWA
MRTDRELLELASLRSLLSYNPESGEFRWLKTNSNASVAGSVAGRSINSDGYKQIVIAGRFYKAHRLAWFYVHGEWPNQIDHINGIRTDNRLSNLRNVSAQHNTHNQRNPHKNNRSGFLGVVARPNGRYQAEIRVNGRKKFIGTFSTPEEASLAYVSAKREMHSGATL
>NC_018828|2253901:2260898|2253901_2254891_+|WP_015039652.1|integrase|DBSCAN-SWA
MGTYRKRGDTWRAEINKAGVRESKTFPTKREAQEWAAARETELATIAVGGITPKSVAQVLQRYCDEISPRNKGHRWERVRIARFLKEEADLCAKLIHTISTADLGAWRDRRLAQVQPVSVRRDIALLRAAWGYARREWRNLKDDPWLDLTMPPEGRHRERIYTQDEVDRLVLALGWEEGQKVVTARQQTAVCFLLSLETAMRSGELLSLEHSQVDLKKRVAQLDQTKNGDRRAVPLSSRAVALFKSLAGLDDAKVFTITPALRDVYFRQGKAIAEVDGATFHDARATALTRLSKKLSILELARMVGHRDPRSLMIYYRESAADIAKKLD
>NC_018828|2253901:2260898|2257192_2258179_-|WP_015039433.1|DBSCAN-SWA
MNNLAVITQDIYNARESFAAVLTDQSISFEKEAGFAIQVLQNNDYTLKVATGNRQSVINAVTNVAAIGISLNPAKRQAYLVPRDGRICLDISYMGLIDLAVATGSIRWAQAELVRSADTFALNGFDAPPTHVFNPFSKERGEIIGAYVVVKTADGDYLTTPMSRDEIDGIMNRSQSVKSGKSSPWKTDYGEMAKKTVVKRAYKYWPKNDRLSEAIHHLNTDGGEGLATTASAPVDPDLLPRLRKAVDAARDAAALEKVWKDGLAEVRATRDMAIYNAFKSAVAARGAVLRGEAVSIEPPPDDGKTIDEPPRDPSDDGFGRDDQGGIQE
>NC_018828|2253901:2260898|2259908_2260898_-|WP_015039654.1|DBSCAN-SWA
MNFEIKNRWTGAVLFTADVPDETESGMVARVALEQAVKSGANLARADLAGANLAGANLADAYLADADLAGANLARANLARANLARANLAGANLADAYLADADLAGANLARANLARANLAGANLADAYLARAYLADAYLADAYLADADLARANLACANLAGADLAGADLARANLAGANLAGAYLARANLAGARNLPVGTEATSPVEPYQRDTRPAAERNAARAARFRELNPTVPVVEALDAKILSAIENGRGGLEMGAWHTCETTHCRAGWAVHLAGEAGYALEREHGPQYAGRMIYMASVGRAPHFFASNELAMADLREQAAQQTKPVA
>NC_018828|2253901:2260898|2256548_2257196_-|WP_015039432.1|DBSCAN-SWA
MNRYILSPHEQGSDGWLLDRCGRVTGSRAADMLAMTAKKEWSTKRADYKFELAIEVLTGMPQGSDYTSKEMQWGIDQEPFARMAYEEASGNVTIESGFMYLPDVAAGCSVDGLFVEDGRRGVLETKCPKSTTHIRYLEAGTLPDQYRPQCLHNVWVTGAEFADFVSFDPRFPQELQLFVCRFTPTAKELADHEKAVLQFLAERDELVAQLKRLAA
>NC_018828|2253901:2260898|2256049_2256430_-|WP_164926388.1|DBSCAN-SWA
MHFDSNTKKNDQPSATLQFTYRTSNDVLSEFSPDLKSSLYRRPRQDEGDMADNADPRLDDPGYLPCLKFPNMQNKVALSEKVVGATVTVHHGIGGKSDLNMDFRAMPFADNSFSLVARKEGDGNAN
>NC_018828|2253901:2260898|2258741_2258951_-|WP_010926412.1|DBSCAN-SWA
MPGTGDTMETTYISDEQAVQVMAQLGGSFMKQLARLWMTADPLRRARLKEAFRDDFDRYRDMAARSDEA
>NC_018828|2253901:2260898|2258361_2258739_-|WP_010926411.1|DBSCAN-SWA
MLPLTYPTECGTAAVVRPLTDAERLAELRRDLDADLHYALVAQRCVRWPYGDPELVAEALYAATIGDAQSEAAFSLLVRAAARGESAVSVGTLFVEWTKLARARLLDTLVELTEDGQRVTFGSRQ
>NC_018828|2253901:2260898|2258182_2258365_-|WP_010926410.1|DBSCAN-SWA
MSRRLIAYLRATRLDLDLAGYAAMVAALAVATGLIGPTLDARSTLTACEGCGKTAVAAKE

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2242819:2242833	attL	NA	NA	NA	NA
WP_015039652.1|2253901_2254891_+|integrase	site-specific integrase	A0A1B1P9F9	Acinetobacter_phage	8.9e-76	44.7
WP_010926403.1|2254887_2255088_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015039429.1|2255200_2255560_-	hypothetical protein	W6MWX0	Pseudomonas_phage	1.6e-11	44.3
WP_015039430.1|2255556_2256060_-	hypothetical protein	A0A1B1W266	Salmonella_phage	1.5e-26	45.8
WP_164926388.1|2256049_2256430_-	hypothetical protein	NA	NA	NA	NA
WP_015039432.1|2256548_2257196_-	YqaJ viral recombinase family protein	A0A0U2BXF3	Paracoccus_phage	8.8e-32	41.4
WP_015039433.1|2257192_2258179_-	phage-related DNA recombination protein	H9C0R8	Aeromonas_phage	4.0e-68	57.8
WP_010926410.1|2258182_2258365_-	hypothetical protein	NA	NA	NA	NA
WP_010926411.1|2258361_2258739_-	hypothetical protein	NA	NA	NA	NA
WP_010926412.1|2258741_2258951_-	hypothetical protein	NA	NA	NA	NA
WP_015039653.1|2258970_2259870_-	hypothetical protein	Q3HQX1	Burkholderia_phage	9.4e-40	68.1
WP_015039654.1|2259908_2260898_-	pentapeptide repeat-containing protein	A0A2P0VPH6	Ralstonia_phage	1.7e-10	45.7
2266920:2266934	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NC_018828|2266104:2288773|DBSCAN-SWA
CATGAGCTACGAGGTCATGAAAGCCTGCCGGCCACTGCAAATGCCTTCCTCGCCGAAGGCCGTGCTGATGGCGCTGGCCGACTATGCAGACGAGGCTGGATCTGCGTGGCCATCGATTCCCACGCTGTGCGAATACACGTGCCTGTCCGAGCGCACTGTTCACGCCGCCATCAAGTGGCTGGAACAGGCCAAGGTGGTGGTGGCCGACCGTGCCAACGGGCGCCACACAACCTACGTTGTCGATGCGAATTCCTTTCAACAACCCCCGCAGCAGTTGCGCCCCCGCAGTAGCTGCACCCCCGCAAATCCCGCAGTCACCCCCGCAGCAGCTGCGGTGGTACCCCCGCAAATCCCGCAGTCACCCCCGCAGCAGCTGCGGTCTAACAACCAAGAACAACCAAGGGAACAACCAGGAACAACCAATAAGCGCGTGCGCGAGCCGAAGGACTCGGGCTTCGACGCGATGAAGGTCGACCTGCCGGACTGGCTGCCAGCGGAAAGCTGGGAGCGCTGGGTCCGCCACCGCGTGCAGCTGAAAAAGCCGATCACCGAGGAAACCGCGCGCCAGCAGATCGAAGACCTGGGGACCTTCCGCGGTCAGGGCCATCAGCCGGACGACGTCATTCGGCACTGCATCGGCAAGAGCTGGCAGGGACTGTTCCCCCCGAAACAAGGCTTCGGGCCACGCCCGGCGCCTGCCGTGAGCGAGGCAGATCGCCGCAAGCAGGAATTCCTGCGCCTGGCGGGCCACGGCGGCAACGACAGCCGCACCATCGACATGGAGCAAGCCTGATGCACAGCCGCGACGTTTCCGCCTTCGCCGAGCTGCTGGCCGGCGTCTTCGATGCCTACAACCGGCTGCCGCCGCAGCCGGCCACGCAGTTGCTCTGGCTGCGCATGCTCGAGCCTTACGAGTTCCCAGCGGTGAGCGCCGCGTTCTCGCAGTACGTGGCCAACGAGGTCAAGTTCCCGCCGACGCCGGCGCAGATCCTGGCGCTGCTTGGTCACGGCACCGGCGACAGCCGGCCCACCGCTGACGAAGCATGGGCCACCGCGCTGGTGTCGCGCGACGAGGCGGAAACGGTGGTCTGGACACTGGAGACGGCGCAAGCCTTCGCGGCGTGCCGCACCGTGCTGGACCTGGGCGACGAGGTGGGCGCGCGCATGGCGTTCAAGGGCGCCTACGACCGGCTGGTGGCGCGGGCTCGCCATGATCGCCAGCCGGTGGCCTGGCAGGTATCCCTCGGTTGGGACCCCGACCGCCGCGAGCGTGCGCTGACCGCCGCCGGAACGGCCGGCCTGTTGCCGGCGCCGCACGTCGCCGCGCTGCTGCCGCCGCCTGATCCTTCGGGTGGTCTGGGCGATGACGCCGTCGCCGCCGAGAACATCGCGCGCCTGCGCAAGCTACTGGCCGGCGCGCTGTCCCCATCCGAGAAACGCCGCCGCGCCGCAGAGCAGGCCGGCCAGGCCGAGCGTGACCGCCTCGACGTCCTGAAGGCCGAGACGGCGGCCAAGGTCGCCCAGCACCAGCAAGGGGTCCGCGCATGAGCAGCTACGCCGAAGCCAGCGCCGCCGTGGGCGGCAACGAAAGCGGGGGCTATGGCGTCTGCGCTGCCTACGGCTGCTGCCTGCCGGGCACGATGACCGACAGCACTCGGGGCGGCAAGGATTGGCACTGCCGCCTGCACTTCGGCGCGCCGCGGTCCGAGTTCGACGATATCAGCGCGCGGGTCCAGAACCGCAAGGCCCTGTTCCTGGCTGCCTACTGGCTGGTCAACCGTTCCAAGGGTGACACCGTCAGCCGCAAGGTGCGGGATCGCATCAAGGCCCTGGGCCGCGCCGACCTGCTGGAGAAGGTGCCCAGCGTGCGCGGCGTCACCGCCTACCACCTGGGCGTGCACATGCTCCGCGTGCTGGGCGACGAGTGCCGCCAGTCCCAGGAACACATGGGCACCCCGAAACGCGCCGGCCAGGGCGCCACCTGGCTGGACCAGACCCAACCCGAGGAAACCGACGCATGAACGCCTCACCCAACCTCACCGACCCCTACGACCCGCTGGCCGGCACGCTGGCCAGGACGGCGATGCAGTGCCAGGCGCGCGGCTGCGACGGCTGCATGGTGTGCAGGCAGACCGCGGCCATGCAGGTACCGCAGGACGCGCTGGAAGGCCGGCGCGCCGAAGTCCTGGCCATTGCCTGCGGGGGATACGCTCTGCCGTTGGAAGGGGGTGGTGTTTTGCCACCCCCGGGTAGCTTCGCGTGCGAGGCAGCGCCTACATCCGATCCGGCAAAAATTAACATCGAGCCCGGCGACCCCTGGGCGCGGCCTGGTGCTGAAACGCCCCGCGCCGCGGCGCAAACCCGCACCACTGTTGGGTTTGACGCTGGTGCTGGAGCTGGGCCTGCGCCAGCGCTGAACGTCAACATCCTGGCGCTGGACCTGGGCACGAAGACCGGCTACGCGCTGCGCCGGCGCGACGGCCGCATGGTGCACGGCACCGAGGAATTCACGCCGCGCGCGAGCTGGGCGCCAGGCCAGAAATGGCTGCGCTTTCGGTCTTGGCTGTCGGCGACCATCACCGAACACAGCATTACGCAGATCGCTTTCGAGGACGTCAAGCGCCATGGCCCGGGCCAGGTACTGGCCGCGCATGCCTATGGCGGCTTCCGCGCCATGCTCGAGATGGTGGCCGACCAGCACCGCGTGGCCCTGGTTCCTTTCGGCGTGGGGCAGATCAAGAAGCATTGGACCGGCTCCGGCGTGGCCAAGAAGGACGACATGCTCATGCAGGCCAAGGTGCGCGGGTTTGCCGCTGTGGACGACAACAACGCCGACGCGCTGGCGATCCTGCATCTGGCCATCGCCAAGGAAAAGCGGGAGTGGGCCGCACCGCCGGCCAAGTCCAAGACGCGGCGCACGCGAAAGGCCGGCGCCGTGGCGCACGAGCGCACAGCATGACCTGGGCCCGCCGATCCGATCGAGGTGATCCGGCCAAGGTGCTGGAGCGCCGCCAGGAGCCGCCGCCTGTGCGCAGTTGCGCTGGCTGCGCGCATATCCGCTTGGTCAAGAGCGAGTTCGACGGGCGCCGCATTCTGACCTGCAGTCATGGCATGCAGGTAGGCCAGCGGTGCCGACTATTCGAGGAGCGACGTAGCGAATGACGACATCCAAGATGCTGCTGGACCGTCTGCCGGCCGACTTCCATGCCCGGCTTGAGAATTGGGGCGAAGTCATGCGTAGCCGGCCGCATTACGCTGTCTCGCCCACCTACGAGGTGTGCCGCAGGCTTGCGAAGCGGGCAGGGCAGGGCGCATGGGGAGGGGAAGAAGGCGTGCGTGAGCTCGACGAAGGCGACGCAGGCCTTATCGAGGCTGCCTGGCGCAATTCGGTCTACCGCATGCTGCATCAGCACCGCGACATCCTGCGAGCCCACTACGTGACGCGTTCCTACTGGTTGGCCACGTGCCGCGCGCTCGGCCTGCGGACGCGGGAGTACGACGACGTGCTGGTGCGGGCGGTAGGCAATTTCGAGGATTTTGTTGCGCGCTACGCCGTAGTTGTGCATAATCCCGCCCAAGACAGACCGACTACCGTCTAACGACGTGACCCGATGCCTATGGCGGGCGCCGCGCGCCCGTCAGAAACGAAGCCCCGAGCCAATGGCCGGGGCTTTTTCGTGGGCGTCTTCCTCCAAAGCGAGAGAACGCACATGCCCAATCAAAACGAAAACGAATTGAAGCGCTACGCCGTCATTGATCTCGATGGCCGCCCCGCTCTGTGCGAAGTGCGTGGGAAGGTCATCGAGGCAGCGTCGTGGAAAGAGGCTCGCAAGATGATCAAGGCCGACGGCGAGTTGCCCGAGGGTATCTAGCTGGCTGAAACCTTCGTCGTCCCCGGACACCGCCCAGCCAGACGGGCGCCCGCGCGGGGGATCAAAGCGCGCGGGACTTTCTCCCCGGCCTCGTCGCCGGGTCTGGTAGACGAGAACCGCACACGCCCAGCTCGCCCAGTGGGCGGGTAAGCCGGATGGGCGCATTCTGAATCACTTTCAACGCGGAATCGATGCCTGCGGCGTCGCTCCCAGAGGGACCGCGCACCATGGCACGACCATCCAAGTACCAGCCGGCGTTCGCCGAGCAGGCGGCGAAGCTCTGCCGCCTCGGCGCCACCGACAAAGACCTGGCCGATTTCTTCGCTGTGACGGAGCGCACGCTCAACACCTGGAAGAAGCAGCACGCCGAGTTTCTTCAGGCCCTAAATGCGGGCAAGACCCTGGCCGATGCCGAGGTGGCCGACAGGCTGTATCAGCGCGCGCTCGGCTACACGCACGCCGAGGACGATATCCGGGTGTGCGACGGCGTGATCGTCACAACGCCCACGACCAAGCATTACCCGCCGGACACGGTGGCGTGCATCTTCTGGTTGAAGAACCGGCGCCCGGACCTCTGGCGCGACAAGCCGGACCCGACGAATGACGACAACGCGCCGCCGCCGGTCAAGGTCGTGATCGAGGTGGTGAACGCGAGCATCCCTGATGCCGACGCTTAACCAGCCCCAGGCTCGGTTCCTGGCGCTGCCGCACAAGTTCCGCGCGTTCGTCGCCGGCTTTGGCAGCGGCAAGACCTGGGTGGGCGGCGCCGGCCTGTGCCGCCATGCCTGGGAATTTCCCCGGGTCAACTCGGGGTACTTCGCGCCGACCTACGGCCAGATCCGGGACATCTTCTACCCGACGATCGAGGAGGTGGCCCACGACTGGGGCCTGGCTGCCAAGATCAACGAGTCGAACAAGGAGGTGCACCTGTTCGCCGGCCGCAAGTACCGCGGCACGGTAATCTGCCGTTCGATGGAGAAGCCTGGCGACATCGTGGGCTTCAAGATCGGCAAAGGGCTGATCGACGAGCTGGACGTGATGAAGGCGGACAAGGCTGCGCTGGCCTGGCGCAAGATCATCGCCCGCCTGCGCCACACCGCGCCCGGGCTGCTCAACGGCGTGGACGTGACCACGACGCCCGAGGGCTTCAAGTTCGTCTACCAGCAGTTCGTCAAGCAGGTCCGCGAGCGGCCCGAGCTGGCCGCGCTGTATGGCCTGGTGCAGGCCAGCACCTACGAGAACGGCAAGAACCTGCCGGAAGACTACATCCCGTCGCTGCGCGCGAGCTACCCGCCGCAGCTCATCGCGGCGTACCTGCGTGGGCAGTTCACCAACCTGACCAGCGGTAGCGTCTACGCCAACTTCGACCGGCGCCTGCACCACACGGACGCGGCCGAGGAGCCGCACGAAGAGCTGCACATCGGCATGGACTTCAACGTGCTGAACATGACGGCCACTGTCAACGTGATACGGGCCGGCCTGCCGCTGACGGTGGGCGAGCTGACGAAGGTCAGGGACACGCCGGAAATGGCTCGGATGCTGAAGGAACGGTTCAAGGACAAGGGGCACGGCGTCACGATCTATCCGGACGCCAGCGGCGGCAACACCAGCAGCAAGAACGCGAGCGAGTCGGACCTGAGCATTCTGCGCAAGGCCGGCTTCACGGTGCGCGTGAACAGCCGAAACCCGTCCGTGAAGGACCGCATCAACGCCGTGAACGGCATGCTGCTCAACGACGAGGGCGCGCGGCGCTGGCTGGTGAACACCGACCGCTGTCCGACGCTGACCGAAGCGCTGGAGCAGCAGGTCTACGACAAGAACGGGGAGCCGGACAAGTCCACCGGGCACGACCACCCGAACGACGCCCAGGGCTATTTCCTGGTGCACCGCTACCCGATCACGCCCACCGGCATGAGTCGCATCAAACTCACAGGAACCTGATCATGCCCGTCGACAGCAAACACCCCCTCTGGCTGGCCAACCAGCCTCGATGGGAACGCTGCCGTACCGCGCTGCAGGGCCAGGACGCCGTGCACGCGGCCGGCGAGAAGTACCTGCCCAAGCTGGCAGGGCAGGACAAGGCGGAATACGACGCCTACAAGGGCCGCGCGATGTTCTACGGCGCCACGGCCCGGACCGAAGAAGCGCTGATCGGTATGGTGTTCCGCAAGGAGCCCACTGTGACGCTGCCGGCGGCACTGCAGCCGATGATCGAGGACGCCGACCTGGCGGGCACGCCGGTGGACACTTTCATCGAGAACGTGACCAAGGAGGTGATCGACGTCACCCGCGTGGGCGTGCTGGTGGATTACCCGGTGGCCAGCGGTGAGTTCATGACCGTGGGTCAGGCCCAGGCCGCCGGCATGCGCCCCTACCTGGCCACCTACAAGGCCGAAGCGATCATCAACTGGCGCACGGCACGCGTGCGCGGCGTGAATCAGCTGGTGCTGGTGGTGCTGGCCGAGTGCTACACCGACCCGAAGGACGAGTTCACCGCCGAGGAAAAGACCCAGTACCGGGTTATGGACCTGGTGGATGGCTTCTACCGCGTGCGCATCTACCGCACCGACCTGAACACCCCGGCGTTCGAGTACACGCCGATGATGAACGGCAAGCGGCTGCCGTACATCCCTTTCGTGCTGATCGGGCGCAACGGCGAGGCGATCGACCCGCAGAAGCCGGTGCTGCTGGACCTGGTCGACGTGAACATGTCGCATTACCGCGGTACGGCCGACTACGAGCACGCGCTGCACTTCACGGCGCTGCCCACGGCGGTGGTAATCGGACACGAACTGAAGGAGGGGCAGGCCCTTAAGATCGGCTCATCGGAAGCGTGGGTATTCACCGACCCCCAAGCAGACGCGAAGTACCTGGAGTTCTCCGGCCAGGGCCTGGACAGCATCAAGGTCAGCCTGGAGCGCAAGGAGGGCATGATGGCCACCCTGGGCGCCCGCATCCTGGCGCCAGAGAAGCGCGACGCCGAGGCGGCCGAGACGGCAAAGATCCACCGCGCTGGCGAGAACAGCGTTCTGGGCGGTATTGCTCTGGGTGTGGGCCGGTCGCTGGCCAAGGCCTTCCGCTGGGCCGCCGAGTGGGCGGGTGCTGGTAGCGGCACGGTCGAGGTGAAACTGAACACCGAGTTCTTCCCCGCCGGCCTGACAGCCCAGGACCTGACCGCCTTGGTTGGTGCGCTCCAGGCTGCAGCAATCAGCCCGCAGACGTTCTACGACAACATGCGCCGTGGCGGCATCATCGACGACGGTGTGACGTTCGAGGAAGAGCAGGACCGCATCGAAGCCGCTGGCCCGGCGCTGGGCACGCTGGGAGGCCAGGATGTCAAGCCTGCAAACGGAGCTGTATGACGCGACCGTTCGGCACGCCATCGACCTGGTGCGCTACAGCAACGGGGTGGTGCGCCGGATCATTGCGCTGCTGAACCAGGTTGACTCTGACCTGGGTGAACAGATCACGCGCGCCATGGAGCGCCTGCCTGCCAGCGCGTTCACGGTGGCGCGGCTGAAAGAGCTGCTGAAGGACGTCCGCACCCTGAACGCCGAGGCGTACCAGCAGGTGCGGGGCGAGCTGGAGAAGGACCTGCGCGACCTGGCGGGCTACGAGATCGGCTACCAGGGCCAGCTATTCGACTCGCTGGGAATCGAGTTCACCACGCGCGGCGTAACGGCCGGGCAGGTGTATGCCGGTGCCATGGCACAGCCGTTCCAGGGGCGCCTGCTGCGCGAATGGATGGCCGGCCTGGAAGCAGGGCGAGCCAGCCGCATCCGCGACGCGGTGCGCATGGGCTACGTGGAGGGACAGACCATCCAGCAGGTGGTGCAGCGCGTGCGCGGCACCCGGGCGAAAGCCTACGCGGACGGCCTGCTGGAGATCGATCGGCGCAACGCGGAGGCCGTGGTGCGCACCGCCATCAGCCACACGGCAGGGTTTGCGCGGGACCGCTGGTACGACGCCAACGACGACATCGTCGGCGCGCTGGCCTGGGTCAGCACGCTGGATTCGCGCACCAGCCAGATGTGTCGGCTGCGCGACGGCCTGCGGTACGAGCCGGATTCGCACAAGCCCATCGGCCATAAGGTGCCCTGGGGCGCCGGGCCTGGCCGGCTGCATTGGCAGTGCCGCAGCACGTCGGTGCCGATCCTCAAGGGCATGGAAGATGACCCGCTCATCGGCACCCGGGCGGCGAAGGATTACCGAGACAGCGCGCGCGGGAAGGGCGAGCAGGTGCGGGCGACAACGACATATGCGGACTGGCTCCGCAGGCAGCCCGCCGCGATCCAGGACGATATCCTGGGCCCGACCCGCGGCGCGCTGTTCCGCAAGGGTGGTGTCGAGCTGGAGAGCTTCTACAACGACCGGGGCGTGTATCTCACGCTGGCCGAGCTGCGTCGCAAGGATGCTGCCGCCTTCGCCCAGGCCGGCGTAGAATAGCGTGCATGCCCCTCCACCTCGTCCCTGACGCTCCGAAGCCGGCGGAAACGGAAAAGGACCGGATCCGGAAGCGGATCAAGGCCCTGCCGAAGCCGAAAGACATGATCCAGTGCCCCCGCTGCGGTGGGCGCGAGGTCATCGAGACGCGCATCGGCGTGTTCGAGACCGCCAGGACGTGGAGTGGCGGCACGAAGGTGCTGCTGTGCGCGCTGTGCTTCATGCGAGGCGAGCGTGTCGTCTTGAAGTGATCTGACCATTACCCATAGGGCCCGCCACTGCGCGGGCCTTCTTCTTTCTAAGCCCTGCTGGCCGAGCCAGTGGGGCTTTTGCTTTTGGGGCTGAGCCCTGCAACCGTCCAGAGGACAACACCATGCCGCTTGACCGTAATGACCCCGAAGTGAAGGCCCTGTTGGAAGAGGTGGCCGCTGAGGCTACCGAGGCGCTGAGCGCCAAGAACAAGGAACTGCTCGCCGAGCTGCGCGCGGCGAAGGCGAAAGCCAAGGGTTCTGAGATCGACCCCGAAGAGCATGCCCGCCTCCAGACCCAGGTCGAGGAGCTGACCGGCAAGCTCGACAAGGTGACGAAGGACAGTGCTCGCCAGATCGAGAGGTTGACCAAGGACCTGGCCGAAAAGGACGACGCCCTGACGCAGCACCTGATCGATGGCGGCCTGTCGTCCGCGCTGGCCAAGGCTGGCGTGGCGCCGCATTTCATGGACGCCGCGAAAGCGATGCTGCGCGGCCAGGCGTCCATCAAGGACGGCGCGGCGGTCATCGGCGACAAGCCGCTGGCTGACCACGTCACCGAGTGGGCCGGTACGGATCAGGGCAAGCACTTCGTCACCGCACCCGCGAATAGCGGCGGCGGCGGGCAGGGCGGCAGTGGTGGTGGCAAGGCCACGGGCAATCTGGGCGGCACCCGCGACGAGCGCGTGGCGGCCCTCAAGGCCCAATTTCCTGAACTCGCGGGCTGATCCCGCACCACGCAAAAGGAACGATCATGTCTCTCTCGCAGATGCAGGTTTTCAACAAGTACTTTATGCCCGCGATCATCGAGACGCTAGGGCAGCAGATCCAGAAATTCAATGCTGCCTCGCGCGGCGCGTTCATGCTGACCACGGCCGGCTTCGAAGGCGACTTCCTCCAGGAATCGTTCTACCAAGCCATCCACGGTGCCCGTCGTCGGGTCGATCGCTACGCTGCCAATGGCAGCGCCTCGCCCACTGATCTGACTCAGCTGAAGCATAGTTCGGTGAAGGTCGCCGGCGGCTTCGGTCCGATCCGGTATGAGCCGTCGCAAATGACATGGCTGGAGAAGCCCACGGCGGAGGGTATCGAGGTAGCTTCGCGCAACTTCGCCGAGGCGCTCTTGCAGGATCAGCTGAATACCGCCATCGCCGCGCTAGTGGCCGCCATCAGTAATCAGGCTACGGCAACGGTCAACGTTTCGGCCAAGACTGGACTGACCTACTCGGTGCTGAACGACGCTCATGCCAAGTTCGGCGATAGCTCCGGCCTGATCGTCGCCAACGTGATGAGTGGCCAGGTCTACCACAAGTTAATCGGCCAGAATCTTGTCAACGCTCAGCAACTGTTTGAGTACGGTGCGGTCACCGTTGTGGACATCCTGGGCAAGACTGTGGTGGTGACTGACGCCCCGGCCTTGTACGCCACGGGCACGCCCAACCTGCAGAAGGTGCTGGGCCTGGTGGCTGGCGCTGCAACCGTGTCCGATGGCGGCGATCTGATTACCAACATCGAAACCTCGAACGGCAAGGAGCGTATCGAAACCACCTTTCAGGCGGACTACACCTTTGGCCTGGGTCTCAAGGGCTACACGTGGGACGAGGCCACCGGCGGCAAGTCGCCGACCGACGCCGAGCTGGCCACGGGCACCAACTGGGACAAGGTGGCCACCGACATCAAGCACACCGCCGGCGTGATCGCCATCGGTGACGCTTCCAAGTAAGGAGCCATCATGACCCAGAAGGCCAAACTGCCCATCTGGTACCTGCCGGGCCCGTTCTACCGGTACGAGCAGGACGTCAAGGCCGAGGCTGCCAAGGCTGGCGTGCGTATCGTCGATGCCAACGCGACCGAGGACCGTAAGGGGGCCGCCAAGGACGTGCCGAAGGTCACCCTGAAGCCGGAATACCGGCCGAAGGGCAAGGCCGAGGCCGCCAAGGAAAAGGAATCCGACCCGCAGCCCAAAGATCCGGCCAAGACCTGACCGCCGATTGACGGTTGCCCCTGCTCACGCGGGGGTTTCCGTCAGCCTGCGGAGATATCCCAATGAAAAATGAGACAACCGGACGCTTTGAAACGGCGCATGGCCTGACCCACACGAAGGAGTATGCCGTGTGGGGCAATATGCTCTACCGCTGCCGGACGCCGTCGGCGCCGCAATACGCCGACTATGGCGGCCGCGGGATCGATGTATGCGAACGGTGGCCTCACTTCGAGGCGTTCCTGGCCGATATGGGCGAATGCCCCCTCGGTATGTCGCTTGAGCGAATTGACGTCAATGGCTCGTATGCGCCCGAGAATTGCCGGTGGGCCACGAGCAGGGAGCAGGCACGTAACCGGCGCAACTCCAGAGTGATGAGCATCTCAGGCGAAACGAAGCCGTTGATCGCATGGGCGGAAGAGTTCGGCGCGCACTGGCCGACGGTGGCGAGCCGTTGGACGCGCGGATGGCGCGGCATCCACATCCTGATGCATACCGGGGAGCGTCTATGTTGATCGTCGAAGACGGAACCGGCCTGCCGAACGCGGATAGCTACGTGAGCGTAGCCGACTGCCAGGCCTATGCCGCCGCTCATGGCCTGGCGTTCGCCGGCGAGGAAGCAGCGCTGGAAGCCGCCCTGCGTAACTCCGCGCTGTATCTGGACGGCGAATACACCTATCGCGGCGAGCGCGCGACCGACACCCAGGCGCTGGAATGGCCGCGCACGGTCGCGACCGGCGTGCCGCGCGAGGTCGTGAACGCCTGCTGCGAGCTGGCGGCGCGCGCGCTGACGGGCCCGCTGTGGCAGGACGTCAGCAGCACCACCGCCGGCGCCGCCATCGAGAAGACCGTCGGCCCGATCACGACGAAGTACGCCAGCGCGGCCGGCGCGCGCAACGACGGCCAGACGCGTTACGCGGGCGTTGCCGCCATGCTGCGCCGCTGGCTGTCGTCCTACGGCTCGTCGGTCAAGCTGGTGAGGTGTTGAGATGGAGAATTTCTTGCGATTGGTGGTACCTGATCCCAGCGGCGAACCGGGATTGCAAGAGTGTTGCGGGGTGCAGCTTTACACGGCGGACGGCATGCCCATCTCCGGCCTGGTGGCGATGAAGCTCGAGAGCAGCACCGATAGGCCGATCTGGCGCGCCACTCTGGTCATGGATATCAACGTTTCCGGGAAGGCCGTCTGATGGCCACCTTCGACTACGCAGACATGGCCGCCACCGCGCAGGAGCTGCTGCTGGAGTTTGGCGGGCCGGTCTCCGTGCGCCAGTTCGTGACGGGCGAGTACGACCCGGATCTTGGCCAGGCGCCCACCACCACGGTCGACAACGCCGGCATCGGCGCGCTATTCGACTACTCGGCGCAGGCCGCGGGCCTGGCCAACATGGCCGGCTCCGTCATCGAGACGGGCGACAAGCAGATGTATCTGGCGCCGGCGCTGGCCGCAGGTGGCGCGATGCCCGAGCCCAAGCCGGCGGACCTGGTGCTGGCGCTGGGCGCCACCTGGCGCGTGGTGACGGTCAAGACGCTGGCGCCCGCCGGCCTGGTGCTGCTGTACGAGCTGCAGTTGAGGCAGGCATGAGCTTCACTGCGGACCTTGGGAAGTTCGCCGCGCGAGCCAAGGGCAACATCGATACGGCCACGCGTCAGGCCACGGTGCTGCTGGCCGAGGGAGTGATCATGAAGTCTCCAATGGACAAAGGACGATTCCGCGCGAACTGGCAATTTTCGGCGGCCGGCATCCAGCGTGCCACGTCGATGGCGGTCGATCCGGATGGGCAGGTAACGCTCCATCGACTGGTAGCCGATATCAAGCAGACACGCGCCGGCGGTGTGACTTACCTGTCGAACTCGCTGCCCTATGCCGTACCGCTGGAAAACGGTTGGTCGAAACAGGCGCCCCAGGGCATGGTCAAGCTGACGGCGCAGGAATTCCAGCAGTATGTAAGCCAGGCGGCGAAGGACGCCAACAAATGAGCCAAGACCTGATCCGTGCCGCCTTCGAGAGGCGACTGAACGACTGGGCGAAGGCGCGCTCGCCGGCGTTGCCCGTGGCGTGGCAGAACACGAAGTTCACGCCGCCCAAGAACGCTATCTACCTGCGCGCCTACGTTCTACCGGCTGCCACGATCAGCCGGGACGCCGCCGGCGATCACCGGCAGTACCGCGGCCTGTTCCAGGTCAACGTGGTGTTGCCCATCGGGTCGGGATCGCGGGCAGCCGAGCAGATCGGGGCGGAGCTCGACGCGCTATTCCCGGTGAACCTGACCATCGCGTCCGGCGGCCTCGCGGTGCGCGTTCGCACCCCCATCAGCAGCGGACAGCCCACGACGGGAGACGCCGATCACACCGTACCCATATCCCTGGGATACGACGTCCAGTTTTACCCGGAGTGAAAAAGAAATGAACGAAGCCAGAATCACGGCGGAACGACTGCGTTCAGTTGTCCATTACGACCCCGAAACGGGCAAGTTCACGCGGTTGGTCCGCCTCGCCCAGCGTCACAACGTGGGCGATGATGCGGCCCATGCCACCGCCAACGGTTATCAGCGCGTCGGCATCGACGGACAGCGGTATCTGGCGCATAGGCTTGCCTGGCTATATGTGTACGGAGCATGGCCCACACAGAATATAGACCATGTGAATGGCGACCGTTCAGACAATCGCATTGCAAACCTTCGGGATGTCCCTCAGGCCGTGAATATGCAGAACCGGCGACACCCCCAGGCTGACAATAAATCAGGCTACCTAGGGGTGTATTGGGAGCGAGGTGCGAAGAAATGGCGCAGTCGCGTACAGGTTGCGGGGAAGGCACACGAGGTCGGGCTGTTCGATGACCCCGCCGTAGCTCATGCGGCGTATGTAGCCAAGAAGCGGAAGCTGCACGAAGGATGCTCGATCTGAAGATTCGGCGTATGCCGATGGCCCGTAAGGGCGCAACTGGAACCCGCCACATGGCGGTTTTTTATTGCCCTCTGGGCTTCGATGAGGGGCCGTTGGCCCCCTAAGGAACTATCATCAGCGCAATATTCCCTAACGGCACCGTGTTCTCGGTATCTACTGAATTGGGTGCGGCTGTTACTGTTTCTGCAATTACGAATGCCAATCCCGCTGTTGCCAGCGCGACGAATCCGCCGAAGGCAGGCACGATCCTAATCATGAAGTCCGGTTGGCCGGAGCTAAACGAACGTGTTGTACGTGCGGTCAACACAGCATCAAACACATTCGCATTGGAGGGGATCGATACGACGAAGGTAGGTAGGTTTTCCAAGGGGCAGGGTATTGGCACGGCAACGCCAGTTTCGACGTGGGTAGACCTGTCGCAGGTTACCAATGTGGCCAAGACAGGAGGTGAACAGCAGTTCTATCAATGGAGGTACGTCGAAGACCGCAACAGTCGTCAACGGCAACGCCCGACCTACAAGAGCGCCAAGTTCATAACTCTGACCCTGGACTACGACCCCGCCTTGGCATGGTATGAGGCGTTGAAGGAAGCCGACGCGGCTAAAGATGCCGTTGTATTGAGGGCGAAGCTGCCCAATAACGACGAACTGTACTACCTGGTGTATCCGTCCTTCGATTCGGACCCCTCGATGGAGCTGGACGCGAATATGCAGAACACCGCTACGTTCTCCATGATGTCCGATTTCACACGTTACGCGCCGCTGGCGTCATAAGGGGGAGGGATGAGCAACATCATATTCAAGCTCCAGCCGGCTCCGACCTTCACCGTACCGGTGGAAATACCCCGGCATGGTGAAGAGCCAGCCAATATCAAGGTCACGTTCAGGCACAAATCACGGGACGAGATGAAGGACTTCCTGGAGCGGGCCGACAAGTCGGATGCGTCCCAGGATATCGCACTGGTGAACGAGATGATCGCCGGCTGGGACGGCCCCGACATGGAATTCAGCGACGAGGCAGTCGGGCTGTTGATCCAGAACTACCAGGGCGCAGTACCGGCATTAGTGCAGGCATACAGCCTCGAGTTGCTCCAGGCCCGCCGAAAAAACTGATTGCCGCGGCGGAGGAAATGTACCGGCCGATGCCGGATAAGGCTCAATTGGCCGAGTTTGGCTTGAGGTCAGACGATTTCCCTGCCGCGGTAATCGAACTGTGGCCGGACAACGTGATGCCCAAGGTGGTATTCGAAGCGATGGGCTCACAGTGGCGCATTGGCTTCGCCGGGCCAACTGGCCTTGATTACGGCGCGCTCCCAGGTGTCATGCGCATGCTTGGCGTCCCACCGGAGCAAGAGACCGATGTGTTCGACGGTGTGCGCGTCATGGAGTCCGCGGCTCTGCGGATGATGAACAAGAAATAGCCCTTCGGGGCGGAAACGGTGCCTTATGGCTGATGAAGTCGCATCCCTCGTACTGCGCGTCGACAGTACCCAGGCCAAAGGTGCGTCTGCTGACCTCGACAAGCTGGCGGTGGCCGGCGCGAAAGCTGAGCAGGCGACGGCTAAGGTTGGTACGGCGGGAAAGGCGGCAGCTACAGGACTTGGAGCCATGGGCAAGGCGGCCAAGGCCGCTCAGGCTCAGACCGCCGCAGCCACTCTGTCAGTGGGCGAAATGCGGACGGCCATGCGTTCACTGCCGATGCAGATGACAGATATCGCAGTAGGCTTGTCCACGGGCCAGTCTCCCTTCTACGTTCTCCTGCAGCAAGGCGGTCAGTTGAAAGACCTGTTCGGGGGCATTGGACCGGCGATCAAGGCGGTGGGTGGCTACGTCGCTGCGTTGGTCACGCCTTTCACCGCCGCCGCCGCCGGGGCCGCTGCTCTGGCGGTGGCGTACCAGCAAGGTGCAGAGGAAGGGAGGCGCTTCACTGCCGCCATCACGCTGACCGGCAACGCGGCCGGCGTGACGGAAAGCCAGCTCGCCGCCATGGCGAAACGGATCTCCGATATTCAGGGCACCACCGGAAACGCTGCCGCCGCCCTAACGAAGCTGGTCGAGACCGGGAAAATCGCCGGCGACTCGATTGAGGGGCTGGGCCGTGCCGCGGTACTGACCGAGGCCGCTACTGGGCGCAGCGTCGACGAAATGGTCAAGGACTACGAGCGGATCGCTGATGCGCCCGCCGAGGCCCTGACCAAGCTGAACGAGCGCTACCACTTCCTGACGCTGGCTGTCTACGACCAGGTTAAGGCGCTGGAGGCCGAGGGGCGGACCCAGGATGCTGCGCGGCTGGCGCTGAACACCTACGCGCAGGCGATGGAGCAGCGCGCCCAGGAGGTGGTTCAGAACATCGGCACCGTGGAGCGTGCGTGGAATGCGGTAACTGGTGCCGCCAAGGGCGCTTGGGACGCCATGCTGGCGATCGGCCGCGAGGATTCGCTGGAGCAGAAACTGGCCCAGGCGCGGAAGAATCTGGAATCGCTGGAAACTTCGCGCTTTCGCACCTTCCTCGATGACGACCGGATCAAGCAGCTGCGTGGCGAGATCGCCGGCCTCGAGGAGCTGGACAAGTGGCAAAAGGCCGCGGCCAAGTCGCGCGCAGATGAAGCGGGGGCAGTCGCTCGCGGGATTCAGGCTCGCAAGCAGATCGAAAAGCAGTTTGCCGGCCCGAAGGGTTCGGTGGCAGCCGGCGTCCGGGAGTTGGAGCGGGCGAGAGAGCAAGAGGCCGCCTTGCGTGCTCAGCTCGCGAGCGCCGTCAAGATCACTTCAGCGCGGCAGGAGTTGGTCAAGTTCGAACAGCGGATCGCAGACCTGAAGGCCAGGGATCAGCTCAGCGCCGACGAAAAGAGCATCCTTGCAAACGAGCAGGCAATCCGGCAGCAGTTGGAGTTGAACGCCGGACTGGCGGATCAGATCGAGTTGCAGAAGGAGGATGTAAAGCTGAAGACGCTGGAGGCGTCGGCACAGGCCACGCTTGCGGCGGACCAGGACCGCTACAACGATCTGCTGGAGGGCTTTACTGCCAGCCCGCGTGTGCGTGAGCAGTTGCAGGCACAGCAGCAGATCTATCGCGACTTTCAGCGTCAGGTGCGCGCCTCTGAGAAAGAAGGCCTCACGCCGGACGCTCTCGCCGCCCGAGTCCAGGTGCTCAAGCTGAACCTGGATCAACGTCTCGAGCTGCTGGCAAGACACTACGAAAAGGTAGGGGTTCTTGAAGGAGACTGGAAGAAGGGCGCCGAGGGGGCCTTCAACGACTACGCGGAGACGGTCGGGAATGTGGCCAGCGCCACGCGCAACGCCTTTGCTGACGCATTCAAGGGGGCAGAGGACGCACTGGTTCAATTCGTGACCACAGGCAAGCTGAGCTTCGCGGAGCTTGCGGATAGCGTCATCGCGGATCTGATGCGGATTACCGTACGGCAGAGCATCACCGGGCCGTTGGCGAGCGTGCTGGGCAGTGTGTTCAGCAACGCATTCGGGTCAGCGCTTCCCGCGACAGCCAGTTGGGCCATGCCTGAGTTGGCCGGCAGACGCGCGACGGGCGGGCCCACCTTACCGCGCCGCCTTTATGAGGTGGCTGAGAACGGACCGGAGCTGTACGACGAGGGTGGCCGCACCTACCTGCTGTCGGGTGGGGACGGTGGACACGTCACGCCCCTGTCGCGTAATGCCTATCGCCCCTCGATGCCTGTGACCGTAAACGTGCACGGTGTGGATTCCCAGCCTCAGGTTCGAGCGCGCCCTGATGCTCGCGGGGGGCTGAGCATCGACCTCATCTTCCGCCAGGTAAAGGACCGGCTTGCCCACGACATCGACGCAGGCGTGGGCAGCTTGCCTCGTGCCCTGGAGCGGCGTTACGGGCTGAACCGTCAACTCGCATAGGTTTCGCATATGACCCTGCCACACTGGCCAGCGGGCTTGCCGTTGGTGGAATTCTCGCGCCAGCCTATCTCGCCTTTTCAGCGCACGGAAATGGAGAACGGGCGTGCACGGCATCGACGGCATACCCGCGTGCATCCCGTTCACGCCCACGTGAGCTTCGTTCTTGATCGGGAGCAGTACGACGTTTATCAGCGGTTCTGCTCCATCGATCTGAACGGTTACGCGGGGTGGTTCCTCATGGCGATGAACGGGCCGGGCGGGCTGAAACTACGGAAGGTTCGATGGTTGCTTCCCGTCCCGCGTGAAGAACGTATCCCCGGTGACCTATGGCGTGTCTCGGGCGAACTGGAATCGATGAGCGATGAGTAATCCCGAACGCCGGGATCTCGTCGCGGCATTTTTTCATTATCAGCACATTGTCGTTGGTGCTTGACCCATGTCACTTGAACAAGCCTTAAAGGAAGCCTACGCCAGTGCGCCGCAAGACCGGGTCGTGTTCGATACGCTTGAACTGCGCCATCCGGCCTTCGTCGACGAACATGGCGAACGCACTGCGGTGCGAGTGGTGTTGGGCTACGAGGATATCTATGCCCGCCTGGAAGCGGAGGCGCCACTGGACGGTGGGAAAGAGGTCCTGTTTCAGGCCGGGGCCTTCAGATTGCGCTTGCCGGGATTTGAGGAAGGCCAGGTCCCTTCCTTGCTTATCACCATAGATGGCGCCAGCGAAAAGATTGTTGACCACGTTGAAGCTGCGGTGCAGTCCCGGTATCCGATCTACGTGACCTACCGCCCCTACGTCTCGACTGACCTGAGCAGACCCCAGATGAACCCGCCCATCACCATGGAACTGAACAAGGTGACCGTCACTGGCGCGTCCGTGTCGGGAACGGCGACGCTTGCGGACGTTCACAACTGGGCGTTTCCGCATCAGCGCTACATGCGCGAGCGCTTTCCGGGCCTGTTCCGATGACCAGCGACGATGTGAATCGTTATATCGGCCTGGCGTGGCAGTTGGGTGCGCGAGGGCCCGGCGCTTATGACTGCTGGGGCCTGCTGCGGGAGTGTCGCGAGCACTACTTCGGTGGCGGCATACCGGACACGGTATTCGGCGAGCAGGCACGCGCGCTCTACGCCGAAAAAATGCGCACAGGGGGTTGGGAGATCGTGATGCAGCCTGAGCATGGCGACGGCGTGCTGTTGCGTGCAGGGAATGACCCGCACGTCGGTATCTACCTCGATCTGGACGGGGGTGGAGTATTGCATGCCATGGAAGGGCGTGGCGTCATCTTTTCCCCCATGCGCGCACTGGTCACCATGGGATTTTCACAGCCTACCTTTTATCGAATCCATGCCTGATATCACCATACGGCGCGATCCGTTCCGACCGCATCTGCGACAAGAGACGGTCGTGGCGCGGCAAGGTACGCGCCTGGACACTATCTTGCGGCGCGAAGGTTTCATCGTCGGACGAGCAGCGCGCCTCGCGCGTACAAGCCCGTTCATTGTGCAGCGCAACGGACGTTGGTTGTTGCAGGCGGCCTGGCATGTTCGGTTGAAGAAGAACGACGTCGTGGTTGTCGTGGTGCTGCCGGCTGGGGGTGGGGGGTCTAATCCGCTGCAAGTGGTCGCTATGGTGGTACTGGCTGCAGTTACGGCGGGTGTAGGAGCATGGGCGACATCTGCGTACGCTGGAGCTGCCGGAGTTGGGGCGACCAGCGCCGCTGCTTTGACTGTTGGTGCTGGAGCGGCGACGGCCGTTGGTCTGGTCGGTGGGATGGTGGTGAACTCACTTTTTCCACCAGCACGGTTGCCAGGCACGCTGCAGCGCGAGAAAGCCAGTCCGACCTATACGTTAAGCGCACAAGGCAATATGGCGCGTCCAATGGAAGCCATACCAGTTCGCTACGGAAGGTATCGTTCGTACCTCGATTTTGCTGCGCAACCCTACACGGAGATGGTCAACAATCAGACCCATCTCTACCAGTTGTTTTGTGTTGGGCAAGGGCGTTATGAAATTGAAGAGATACGAATCGAAGAGACTCCGATAGGAAATTTTTCGGAGGTCGAGTATGAGGTGGTGGAGCCTGGAGGGCAGGTAACGCTGTTTCCAGACAATGTCGTCACTTCTGCTGAAGTACAAGGTATTGAGTTACCTGCGATCAATGTGGAAGGAGCCGGGCCTAAAGGGCCGTTCGCAGCAAACCCGCCGGGTACTCTGGCCAGTGAAATCGCTATAGATGTCCTCCTGCCAAAGGGGTTGTTCTACGCGGCTCATGATGGGACCTTGGAATCGGCTGGTACCGGCGTCAATGTGTACGCGCGCCAAATCGATGATTCAGGAAGGCCGATTGGCACTACGATCCTTCTGGGTAAGGAGAACATTGTCGCGGCAACGCTTACGCCCCAATACCGGACATTTCGGTACAAGGTGGAGCCTGCCCGCTGGGAGGTTAGCGTAGAGCGAAATTCTGGCCATCTTGCTGAGCGCGCTACCCGTATGATCCGCGACGTGACATGGTTAGGGCTGCGGTCCTACCTGCCATCTAAGAGGACTTATGGAAACGTCACGATGCTGGCGGTAGCCATGCGCGCGACGGGTAATCTGAACCAAACCACCGCGCGGCGGATCAATATCATCGCCACCCGGCGTTTGCGAACCTGGGATCCGGTTCAAGGGTGGTCCAAGGACCTTAAACCTACTCGTAATCCTGCCTGGGCGATCGCCGATGCGTGCACGGATCGGGAGTATGGGCGAGGGCTGCCGGACAGCCGCATCAATCTGGCGGCACTCTATCGTTTGGCAAAGGTTTGGGATGAGCGGGGCGATTGGTTCGACGGCGTTTTTGACGTTAGTACGACATTCTGGGAAGCAGTGACGCAGGTCGCCCGTGCTGGGCGGGCGCTACCGATCTATCACGCAGGCGTGATAGATGTCATCAGAGATGAGCCGAAAACCGTGCGAACGCAGATGTTCACACCCGCCAATATCGTGGCGCGTTCGTTTTCCGTTGACTATGTGTTCCCCGCGCATGACGACCCGGACTACATCATTGTCGAGTTCGTCAACGAGAGGACTTGGAAGGACGACGAGGTGGAGTGTGCTTGGCCTGGTGCGGCCAAGCGGCGGCCTTATCGGTTGCGACTCATGGGCGTGACCGGCCGGGCGCAGGCATGGCGTGAGGGCATGGCGCTATTGGCCCGCAACCGGGACCAGCGGCGTTTTGCTAGTTTTCAGACTGAGTTGGAAGGGGCCATTCCGGGTTATGCCGATCTGGTCGAGATCAGCCATGATGTTCCCAAGTGGGGGCTGTCGGGAATCGTGGAAGACTACGATCCTCGTGCGCTCCGGCTTACTACGTCCGAGCATTTGCAGTGGTGGCAAGGCCAGAACCACTATATCAGCTTGCGCGGCCGAGATGGCGTACCTGCCGGACCTTTTCGCGTCGAGCCGGGCACGCATGAGCGTGAGATGCGCATTGTGGATTTGGTTGATGGGCAAGGTTTGTATGTTTCGACAGGGGAAGCTGAAGAGCCTACCCACTACACGTTTGGTCCAGGCGAGCGGCGGGCATTGCTTGCCCAGGTAATGCGGGCGGTGCCGAGCGAGGCTGGGTTATGGACGCTGGACGTGGTGAACTATGCGCCATCGGTGCATACAGCGGAACTGGGTGGGCAGGAACCTGAGTTCGCTTCTCCTTCTTTGCTACCCATCGTACCGCTGGGGCCGATTGTTGATAGCGTGACGGTGTTTTCCGGTCCTCGACCAGGACAACAGATCGTATCGGCCACGCCGGCCTCCGGTGCCTATCGCTACGAGTTTGAAGCCAGTGACGATGGAGGCGTACATTGGCAGCCTCTGGGGATGGCCGAGTTACCGAGTCTAGAGGTTTACCTTCGCGCGGGATCCTGGCAGGTGCGGGTTCGTGGTATCGGCGCATTGTCCGGGCCGTGGAAGACTTGGCAGGGCAACGTTAGCGCAAGCGCCGCACTACCGCCAAAGCTCTCCGCGTTGACGACGATAAGCCAAGTGATGGCGATTGAATTGGCGTGGACTGTGCCGGACGCTCCATGGATGAGCTCAGTCGAGATTTGGGAGTCTTCGACTCCCAACCTCGGGGATGCTTCGTTGATGGGAGAGTTTCGGTTGCCTCAAAGCCGCTTTACCCGATTCGGCCTGAGCCATGGTACGAGAATTTGGTTCTGGGGGCGAATACGCGATGTGGCTGGACAGTTGGGACCATGGTATCCCGATGGGCAGGGCGTGCTGGGTAGTGCAAGTAGCGATGCGGGCAAGATTCTTGACTACTTGAGTGGCCAGATCGGGCCGGAGCAGTTGACGCGTGATTTGACGCAGACCATTTCGGGGATGGAGCGCAACATCAATACGGTCACTGCGAAGCTGGATCAGGAAAGAGAGGAGCGCCTTAGCCAGGATGGCGCATTGGCTCGTCGAGTCGAAGATGCGATTGCAGCAAATGGTGCGGGTGCAACGGCTGTAAAGCAGACCAGCGCGGCACTTGCCAGCCTAGATGGACGTCTGCGGGCCAACTGGTCTGTCCAGACTCAGGTCGCCCAAGACGGCAAGGTATACGCGGCTGGCATGGCGCTCGGTGCTTATGCCGGCGAAGGTGGGCAGGTTCAAACGTCGGTGTACTTCCTGGCTGATCGCTTCGCCTTTCTGAACCTAGCCAACGGGAAGGTATCGAGCCCCTTCGTGATCCAGAACGGGCAGACCTTCTTGAACCAAGCGTTCATCGGGAAGGCGTGGATTAAGAGCGCGCAGGTCGAGAGCCTGGACGCGGGCAAGATCGTGGCTGGTGTCATGAGCGCCGATCGGATCAACGCCAATTCTCTGATAGCGAAGCTGGCCAGCTTCACCACGGCCTACGTCAAGACTGCCCATATAGGTGTTGCGCAGGTCGATACGCTGCGCCTCGCATCTGATGCTGTTGTGACAGGCTCTCACAGCATCATCTCCAAGTCTTTGGGGCGAGGGCGAGAGGCATGGGAGTGGGCGACTGTCGCGACCGGTAGCTTGTACCTGCCTTATGGCGGTTCGGTAGTAGTCTTTATGCAGTACGCGCAATCGGGAGGGCAGTTTCCATTTGGTGGGCGGTTTCCATTTGGTGGGCGTAACGACATTGTTTCCGTTTCCATCGACGGAGAGATCATCCCGAATACTTTGTCGAATCCTAGCAATGGGGCAGCCATGATTACCTGGATCAGCGATACCTTGCCGGAGGGGAAAACGATCTCTTGGTCGATCCAAGCCAGACATCCTGTCGATGGTAGGTCCTACATAAGCGGCCGCGTAGCAGTACTGGCGATCCAGCGGTGA

Protein sequences of DBSCAN-SWA_4

>NC_018828|2266104:2288773|2273365_2274421_+|WP_015039668.1|DBSCAN-SWA
MRYSNGVVRRIIALLNQVDSDLGEQITRAMERLPASAFTVARLKELLKDVRTLNAEAYQQVRGELEKDLRDLAGYEIGYQGQLFDSLGIEFTTRGVTAGQVYAGAMAQPFQGRLLREWMAGLEAGRASRIRDAVRMGYVEGQTIQQVVQRVRGTRAKAYADGLLEIDRRNAEAVVRTAISHTAGFARDRWYDANDDIVGALAWVSTLDSRTSQMCRLRDGLRYEPDSHKPIGHKVPWGAGPGRLHWQCRSTSVPILKGMEDDPLIGTRAAKDYRDSARGKGEQVRATTTYADWLRRQPAAIQDDILGPTRGALFRKGGVELESFYNDRGVYLTLAELRRKDAAAFAQAGVE
>NC_018828|2266104:2288773|2275420_2276389_+|WP_015039670.1|DBSCAN-SWA
MSLSQMQVFNKYFMPAIIETLGQQIQKFNAASRGAFMLTTAGFEGDFLQESFYQAIHGARRRVDRYAANGSASPTDLTQLKHSSVKVAGGFGPIRYEPSQMTWLEKPTAEGIEVASRNFAEALLQDQLNTAIAALVAAISNQATATVNVSAKTGLTYSVLNDAHAKFGDSSGLIVANVMSGQVYHKLIGQNLVNAQQLFEYGAVTVVDILGKTVVVTDAPALYATGTPNLQKVLGLVAGAATVSDGGDLITNIETSNGKERIETTFQADYTFGLGLKGYTWDEATGGKSPTDAELATGTNWDKVATDIKHTAGVIAIGDASK
>NC_018828|2266104:2288773|2284401_2284791_+|WP_015039680.1|DBSCAN-SWA
MTSDDVNRYIGLAWQLGARGPGAYDCWGLLRECREHYFGGGIPDTVFGEQARALYAEKMRTGGWEIVMQPEHGDGVLLRAGNDPHVGIYLDLDGGGVLHAMEGRGVIFSPMRALVTMGFSQPTFYRIHA
>NC_018828|2266104:2288773|2276398_2276650_+|WP_015039671.1|DBSCAN-SWA
MTQKAKLPIWYLPGPFYRYEQDVKAEAAKAGVRIVDANATEDRKGAAKDVPKVTLKPEYRPKGKAEAAKEKESDPQPKDPAKT
>NC_018828|2266104:2288773|2277836_2278232_+|WP_010931439.1|DBSCAN-SWA
MATFDYADMAATAQELLLEFGGPVSVRQFVTGEYDPDLGQAPTTTVDNAGIGALFDYSAQAAGLANMAGSVIETGDKQMYLAPALAAGGAMPEPKPADLVLALGATWRVVTVKTLAPAGLVLLYELQLRQA
>NC_018828|2266104:2288773|2271918_2273337_+|WP_015039667.1|DBSCAN-SWA
MPVDSKHPLWLANQPRWERCRTALQGQDAVHAAGEKYLPKLAGQDKAEYDAYKGRAMFYGATARTEEALIGMVFRKEPTVTLPAALQPMIEDADLAGTPVDTFIENVTKEVIDVTRVGVLVDYPVASGEFMTVGQAQAAGMRPYLATYKAEAIINWRTARVRGVNQLVLVVLAECYTDPKDEFTAEEKTQYRVMDLVDGFYRVRIYRTDLNTPAFEYTPMMNGKRLPYIPFVLIGRNGEAIDPQKPVLLDLVDVNMSHYRGTADYEHALHFTALPTAVVIGHELKEGQALKIGSSEAWVFTDPQADAKYLEFSGQGLDSIKVSLERKEGMMATLGARILAPEKRDAEAAETAKIHRAGENSVLGGIALGVGRSLAKAFRWAAEWAGAGSGTVEVKLNTEFFPAGLTAQDLTALVGALQAAAISPQTFYDNMRRGGIIDDGVTFEEEQDRIEAAGPALGTLGGQDVKPANGAV
>NC_018828|2266104:2288773|2269261_2269702_+|WP_015039664.1|DBSCAN-SWA
MTTSKMLLDRLPADFHARLENWGEVMRSRPHYAVSPTYEVCRRLAKRAGQGAWGGEEGVRELDEGDAGLIEAAWRNSVYRMLHQHRDILRAHYVTRSYWLATCRALGLRTREYDDVLVRAVGNFEDFVARYAVVVHNPAQDRPTTV
>NC_018828|2266104:2288773|2277636_2277837_+|WP_010931440.1|DBSCAN-SWA
MENFLRLVVPDPSGEPGLQECCGVQLYTADGMPISGLVAMKLESSTDRPIWRATLVMDINVSGKAV
>NC_018828|2266104:2288773|2274791_2275394_+|WP_015039669.1|DBSCAN-SWA
MPLDRNDPEVKALLEEVAAEATEALSAKNKELLAELRAAKAKAKGSEIDPEEHARLQTQVEELTGKLDKVTKDSARQIERLTKDLAEKDDALTQHLIDGGLSSALAKAGVAPHFMDAAKAMLRGQASIKDGAAVIGDKPLADHVTEWAGTDQGKHFVTAPANSGGGGQGGSGGGKATGNLGGTRDERVAALKAQFPELAG
>NC_018828|2266104:2288773|2279808_2280327_+|WP_015039676.1|DBSCAN-SWA
MKSGWPELNERVVRAVNTASNTFALEGIDTTKVGRFSKGQGIGTATPVSTWVDLSQVTNVAKTGGEQQFYQWRYVEDRNSRQRQRPTYKSAKFITLTLDYDPALAWYEALKEADAAKDAVVLRAKLPNNDELYYLVYPSFDSDPSMELDANMQNTATFSMMSDFTRYAPLAS
>NC_018828|2266104:2288773|2270638_2271916_+|WP_010931447.1|terminase|DBSCAN-SWA
MPTLNQPQARFLALPHKFRAFVAGFGSGKTWVGGAGLCRHAWEFPRVNSGYFAPTYGQIRDIFYPTIEEVAHDWGLAAKINESNKEVHLFAGRKYRGTVICRSMEKPGDIVGFKIGKGLIDELDVMKADKAALAWRKIIARLRHTAPGLLNGVDVTTTPEGFKFVYQQFVKQVRERPELAALYGLVQASTYENGKNLPEDYIPSLRASYPPQLIAAYLRGQFTNLTSGSVYANFDRRLHHTDAAEEPHEELHIGMDFNVLNMTATVNVIRAGLPLTVGELTKVRDTPEMARMLKERFKDKGHGVTIYPDASGGNTSSKNASESDLSILRKAGFTVRVNSRNPSVKDRINAVNGMLLNDEGARRWLVNTDRCPTLTEALEQQVYDKNGEPDKSTGHDHPNDAQGYFLVHRYPITPTGMSRIKLTGT
>NC_018828|2266104:2288773|2283871_2284405_+|WP_015039679.1|DBSCAN-SWA
MSLEQALKEAYASAPQDRVVFDTLELRHPAFVDEHGERTAVRVVLGYEDIYARLEAEAPLDGGKEVLFQAGAFRLRLPGFEEGQVPSLLITIDGASEKIVDHVEAAVQSRYPIYVTYRPYVSTDLSRPQMNPPITMELNKVTVTGASVSGTATLADVHNWAFPHQRYMRERFPGLFR
>NC_018828|2266104:2288773|2280999_2283435_+|WP_015039678.1|tail|DBSCAN-SWA
MADEVASLVLRVDSTQAKGASADLDKLAVAGAKAEQATAKVGTAGKAAATGLGAMGKAAKAAQAQTAAATLSVGEMRTAMRSLPMQMTDIAVGLSTGQSPFYVLLQQGGQLKDLFGGIGPAIKAVGGYVAALVTPFTAAAAGAAALAVAYQQGAEEGRRFTAAITLTGNAAGVTESQLAAMAKRISDIQGTTGNAAAALTKLVETGKIAGDSIEGLGRAAVLTEAATGRSVDEMVKDYERIADAPAEALTKLNERYHFLTLAVYDQVKALEAEGRTQDAARLALNTYAQAMEQRAQEVVQNIGTVERAWNAVTGAAKGAWDAMLAIGREDSLEQKLAQARKNLESLETSRFRTFLDDDRIKQLRGEIAGLEELDKWQKAAAKSRADEAGAVARGIQARKQIEKQFAGPKGSVAAGVRELERAREQEAALRAQLASAVKITSARQELVKFEQRIADLKARDQLSADEKSILANEQAIRQQLELNAGLADQIELQKEDVKLKTLEASAQATLAADQDRYNDLLEGFTASPRVREQLQAQQQIYRDFQRQVRASEKEGLTPDALAARVQVLKLNLDQRLELLARHYEKVGVLEGDWKKGAEGAFNDYAETVGNVASATRNAFADAFKGAEDALVQFVTTGKLSFAELADSVIADLMRITVRQSITGPLASVLGSVFSNAFGSALPATASWAMPELAGRRATGGPTLPRRLYEVAENGPELYDEGGRTYLLSGGDGGHVTPLSRNAYRPSMPVTVNVHGVDSQPQVRARPDARGGLSIDLIFRQVKDRLAHDIDAGVGSLPRALERRYGLNRQLA
>NC_018828|2266104:2288773|2277155_2277635_+|WP_015039673.1|DBSCAN-SWA
MLIVEDGTGLPNADSYVSVADCQAYAAAHGLAFAGEEAALEAALRNSALYLDGEYTYRGERATDTQALEWPRTVATGVPREVVNACCELAARALTGPLWQDVSSTTAGAAIEKTVGPITTKYASAAGARNDGQTRYAGVAAMLRRWLSSYGSSVKLVRC
>NC_018828|2266104:2288773|2274426_2274669_+|WP_014905397.1|DBSCAN-SWA
MPLHLVPDAPKPAETEKDRIRKRIKALPKPKDMIQCPRCGGREVIETRIGVFETARTWSGGTKVLLCALCFMRGERVVLK
>NC_018828|2266104:2288773|2280683_2280974_+|WP_015039677.1|DBSCAN-SWA
MYRPMPDKAQLAEFGLRSDDFPAAVIELWPDNVMPKVVFEAMGSQWRIGFAGPTGLDYGALPGVMRMLGVPPEQETDVFDGVRVMESAALRMMNKK
>NC_018828|2266104:2288773|2266895_2267651_+|WP_015039446.1|DBSCAN-SWA
MHSRDVSAFAELLAGVFDAYNRLPPQPATQLLWLRMLEPYEFPAVSAAFSQYVANEVKFPPTPAQILALLGHGTGDSRPTADEAWATALVSRDEAETVVWTLETAQAFAACRTVLDLGDEVGARMAFKGAYDRLVARARHDRQPVAWQVSLGWDPDRRERALTAAGTAGLLPAPHVAALLPPPDPSGGLGDDAVAAENIARLRKLLAGALSPSEKRRRAAEQAGQAERDRLDVLKAETAAKVAQHQQGVRA
>NC_018828|2266104:2288773|2276712_2277162_+|WP_015039672.1|DBSCAN-SWA
MKNETTGRFETAHGLTHTKEYAVWGNMLYRCRTPSAPQYADYGGRGIDVCERWPHFEAFLADMGECPLGMSLERIDVNGSYAPENCRWATSREQARNRRNSRVMSISGETKPLIAWAEEFGAHWPTVASRWTRGWRGIHILMHTGERLC
>NC_018828|2266104:2288773|2279053_2279554_+|WP_010931436.1|DBSCAN-SWA
MNEARITAERLRSVVHYDPETGKFTRLVRLAQRHNVGDDAAHATANGYQRVGIDGQRYLAHRLAWLYVYGAWPTQNIDHVNGDRSDNRIANLRDVPQAVNMQNRRHPQADNKSGYLGVYWERGAKKWRSRVQVAGKAHEVGLFDDPAVAHAAYVAKKRKLHEGCSI
>NC_018828|2266104:2288773|2283444_2283804_+|WP_010931432.1|DBSCAN-SWA
MTLPHWPAGLPLVEFSRQPISPFQRTEMENGRARHRRHTRVHPVHAHVSFVLDREQYDVYQRFCSIDLNGYAGWFLMAMNGPGGLKLRKVRWLLPVPREERIPGDLWRVSGELESMSDE
>NC_018828|2266104:2288773|2267647_2268124_+|WP_015039661.1|DBSCAN-SWA
MSSYAEASAAVGGNESGGYGVCAAYGCCLPGTMTDSTRGGKDWHCRLHFGAPRSEFDDISARVQNRKALFLAAYWLVNRSKGDTVSRKVRDRIKALGRADLLEKVPSVRGVTAYHLGVHMLRVLGDECRQSQEHMGTPKRAGQGATWLDQTQPEETDA
>NC_018828|2266104:2288773|2284783_2288773_+|WP_015039681.1|DBSCAN-SWA
MPDITIRRDPFRPHLRQETVVARQGTRLDTILRREGFIVGRAARLARTSPFIVQRNGRWLLQAAWHVRLKKNDVVVVVVLPAGGGGSNPLQVVAMVVLAAVTAGVGAWATSAYAGAAGVGATSAAALTVGAGAATAVGLVGGMVVNSLFPPARLPGTLQREKASPTYTLSAQGNMARPMEAIPVRYGRYRSYLDFAAQPYTEMVNNQTHLYQLFCVGQGRYEIEEIRIEETPIGNFSEVEYEVVEPGGQVTLFPDNVVTSAEVQGIELPAINVEGAGPKGPFAANPPGTLASEIAIDVLLPKGLFYAAHDGTLESAGTGVNVYARQIDDSGRPIGTTILLGKENIVAATLTPQYRTFRYKVEPARWEVSVERNSGHLAERATRMIRDVTWLGLRSYLPSKRTYGNVTMLAVAMRATGNLNQTTARRINIIATRRLRTWDPVQGWSKDLKPTRNPAWAIADACTDREYGRGLPDSRINLAALYRLAKVWDERGDWFDGVFDVSTTFWEAVTQVARAGRALPIYHAGVIDVIRDEPKTVRTQMFTPANIVARSFSVDYVFPAHDDPDYIIVEFVNERTWKDDEVECAWPGAAKRRPYRLRLMGVTGRAQAWREGMALLARNRDQRRFASFQTELEGAIPGYADLVEISHDVPKWGLSGIVEDYDPRALRLTTSEHLQWWQGQNHYISLRGRDGVPAGPFRVEPGTHEREMRIVDLVDGQGLYVSTGEAEEPTHYTFGPGERRALLAQVMRAVPSEAGLWTLDVVNYAPSVHTAELGGQEPEFASPSLLPIVPLGPIVDSVTVFSGPRPGQQIVSATPASGAYRYEFEASDDGGVHWQPLGMAELPSLEVYLRAGSWQVRVRGIGALSGPWKTWQGNVSASAALPPKLSALTTISQVMAIELAWTVPDAPWMSSVEIWESSTPNLGDASLMGEFRLPQSRFTRFGLSHGTRIWFWGRIRDVAGQLGPWYPDGQGVLGSASSDAGKILDYLSGQIGPEQLTRDLTQTISGMERNINTVTAKLDQEREERLSQDGALARRVEDAIAANGAGATAVKQTSAALASLDGRLRANWSVQTQVAQDGKVYAAGMALGAYAGEGGQVQTSVYFLADRFAFLNLANGKVSSPFVIQNGQTFLNQAFIGKAWIKSAQVESLDAGKIVAGVMSADRINANSLIAKLASFTTAYVKTAHIGVAQVDTLRLASDAVVTGSHSIISKSLGRGREAWEWATVATGSLYLPYGGSVVVFMQYAQSGGQFPFGGRFPFGGRNDIVSVSIDGEIIPNTLSNPSNGAAMITWISDTLPEGKTISWSIQARHPVDGRSYISGRVAVLAIQR
>NC_018828|2266104:2288773|2266104_2266896_+|WP_164926532.1|DBSCAN-SWA
MSYEVMKACRPLQMPSSPKAVLMALADYADEAGSAWPSIPTLCEYTCLSERTVHAAIKWLEQAKVVVADRANGRHTTYVVDANSFQQPPQQLRPRSSCTPANPAVTPAAAAVVPPQIPQSPPQQLRSNNQEQPREQPGTTNKRVREPKDSGFDAMKVDLPDWLPAESWERWVRHRVQLKKPITEETARQQIEDLGTFRGQGHQPDDVIRHCIGKSWQGLFPPKQGFGPRPAPAVSEADRRKQEFLRLAGHGGNDSRTIDMEQA
>NC_018828|2266104:2288773|2278228_2278627_+|WP_015039674.1|DBSCAN-SWA
MSFTADLGKFAARAKGNIDTATRQATVLLAEGVIMKSPMDKGRFRANWQFSAAGIQRATSMAVDPDGQVTLHRLVADIKQTRAGGVTYLSNSLPYAVPLENGWSKQAPQGMVKLTAQEFQQYVSQAAKDANK
>NC_018828|2266104:2288773|2270166_2270652_+|WP_015039666.1|DBSCAN-SWA
MPAASLPEGPRTMARPSKYQPAFAEQAAKLCRLGATDKDLADFFAVTERTLNTWKKQHAEFLQALNAGKTLADAEVADRLYQRALGYTHAEDDIRVCDGVIVTTPTTKHYPPDTVACIFWLKNRRPDLWRDKPDPTNDDNAPPPVKVVIEVVNASIPDADA
>NC_018828|2266104:2288773|2280336_2280666_+|WP_003813412.1|DBSCAN-SWA
MSNIIFKLQPAPTFTVPVEIPRHGEEPANIKVTFRHKSRDEMKDFLERADKSDASQDIALVNEMIAGWDGPDMEFSDEAVGLLIQNYQGAVPALVQAYSLELLQARRKN
>NC_018828|2266104:2288773|2269813_2269975_+|WP_161781333.1|DBSCAN-SWA
MPNQNENELKRYAVIDLDGRPALCEVRGKVIEAASWKEARKMIKADGELPEGI
>NC_018828|2266104:2288773|2268243_2269062_+|WP_015039662.1|DBSCAN-SWA
MQVPQDALEGRRAEVLAIACGGYALPLEGGGVLPPPGSFACEAAPTSDPAKINIEPGDPWARPGAETPRAAAQTRTTVGFDAGAGAGPAPALNVNILALDLGTKTGYALRRRDGRMVHGTEEFTPRASWAPGQKWLRFRSWLSATITEHSITQIAFEDVKRHGPGQVLAAHAYGGFRAMLEMVADQHRVALVPFGVGQIKKHWTGSGVAKKDDMLMQAKVRGFAAVDDNNADALAILHLAIAKEKREWAAPPAKSKTRRTRKAGAVAHERTA
>NC_018828|2266104:2288773|2278623_2279046_+|WP_015039675.1|DBSCAN-SWA
MSQDLIRAAFERRLNDWAKARSPALPVAWQNTKFTPPKNAIYLRAYVLPAATISRDAAGDHRQYRGLFQVNVVLPIGSGSRAAEQIGAELDALFPVNLTIASGGLAVRVRTPISSGQPTTGDADHTVPISLGYDVQFYPE

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164926532.1|2266104_2266896_+	helix-turn-helix domain-containing protein	A0A1B0YZZ0	Pseudomonas_phage	9.2e-15	45.4
WP_015039446.1|2266895_2267651_+	hypothetical protein	U6C6D0	Ralstonia_phage	1.0e-26	38.0
WP_015039661.1|2267647_2268124_+	phage protein	NA	NA	NA	NA
WP_015039662.1|2268243_2269062_+	phage protein	K4ICN3	Acidithiobacillus_phage	1.0e-21	43.6
WP_015039664.1|2269261_2269702_+	hypothetical protein	NA	NA	NA	NA
WP_161781333.1|2269813_2269975_+	hypothetical protein	NA	NA	NA	NA
WP_015039666.1|2270166_2270652_+	hypothetical protein	C7U0W1	Enterobacteria_phage	1.2e-38	62.3
WP_010931447.1|2270638_2271916_+|terminase	terminase	A0A1B1P9C9	Acinetobacter_phage	2.4e-150	64.7
WP_015039667.1|2271918_2273337_+	DUF4055 domain-containing protein	R9TF43	Synechococcus_phage	8.2e-99	41.9
WP_015039668.1|2273365_2274421_+	hypothetical protein	A0A0H5BBX3	Pseudomonas_phage	5.2e-98	50.8
WP_014905397.1|2274426_2274669_+	hypothetical protein	A0A0H5AUE5	Pseudomonas_phage	1.5e-16	54.5
WP_015039669.1|2274791_2275394_+	hypothetical protein	R9TF81	Synechococcus_phage	2.6e-30	47.5
WP_015039670.1|2275420_2276389_+	hypothetical protein	R9TJ64	Synechococcus_phage	1.3e-124	72.3
WP_015039671.1|2276398_2276650_+	hypothetical protein	NA	NA	NA	NA
WP_015039672.1|2276712_2277162_+	hypothetical protein	I6WLM5	Burkholderia_virus	2.2e-29	51.6
WP_015039673.1|2277155_2277635_+	hypothetical protein	A0A088C4X4	Shewanella_sp._phage	1.2e-12	39.3
WP_010931440.1|2277636_2277837_+	hypothetical protein	NA	NA	NA	NA
WP_010931439.1|2277836_2278232_+	hypothetical protein	A0A2D2W284	Stenotrophomonas_phage	7.8e-07	35.0
WP_015039674.1|2278228_2278627_+	hypothetical protein	A0A088FBW9	Salmonella_phage	2.6e-18	37.8
WP_015039675.1|2278623_2279046_+	DUF4128 domain-containing protein	I6PDJ8	Cronobacter_phage	2.6e-08	29.2
WP_010931436.1|2279053_2279554_+	HNH endonuclease	A0A1I9SEX5	Klebsiella_phage	4.4e-31	45.1
WP_015039676.1|2279808_2280327_+	hypothetical protein	A0A1S5R1H0	Pseudomonas_phage	5.4e-24	38.3
WP_003813412.1|2280336_2280666_+	hypothetical protein	A0A2H4J121	uncultured_Caudovirales_phage	2.9e-15	44.0
WP_015039677.1|2280683_2280974_+	DUF1799 domain-containing protein	A0A2H4JBP7	uncultured_Caudovirales_phage	2.0e-15	43.0
WP_015039678.1|2280999_2283435_+|tail	phage tail tape measure protein	A0A1V0E821	Vibrio_phage	4.6e-97	34.7
WP_010931432.1|2283444_2283804_+	hypothetical protein	NA	NA	NA	NA
WP_015039679.1|2283871_2284405_+	DUF1833 family protein	A5A3Q9	Burkholderia_phage	1.3e-41	48.0
WP_015039680.1|2284401_2284791_+	C40 family peptidase	A0A0G3EYJ9	Achromobacter_phage	1.8e-35	50.0
WP_015039681.1|2284783_2288773_+	DUF1983 domain-containing protein	A0A0B5A1N2	Achromobacter_phage	1.4e-215	40.9

Sequences of DBSCAN-SWA_5

Nucleotide sequences of DBSCAN-SWA_5

>NC_018828|2298072:2306530|DBSCAN-SWA
CATGGCAACCGGTATCGTCAAGTGGTTCAATGCCGAAAAGGGCTATGGATTCATCATGCCCGATGACGGCAGTAAAGATCTTTTTGCACATTATTCCGAGATCCGCAGCGAGGGCTACAAATCGCTGCAGGAGAATCAGCGCGTATCCTTCGAGGTGGGACAAGGGCCCAAGGGGCCAAGCGCCAAGAACATAAAAGTCATCGCCTGACGGCCCCGTTGTCGCCGCGGCCGGCGCAGTTCCGGCGGGCCGCATGAAAAAAGCCCCATTGCCTCGCGGCAGTGGGGCTTTTTGTTGCGCGCCGTATTCAGTGCGACGGATGGGCGCCGTGCCCGACGGACTGGCTGGTCAGGCGGTCGACATACGCGATGCCGATCGCCGACAGGATGAAGACCACGTGGATGATGGTCTGCCACATCACGCCGGTTTCGGTGAAGCGGGAATTGGGCGAGCCCAGGTTGCTCGCCTCGATGAAGGTGCGCAGCAGGTGGATCGACGAGATGCCGATGATGGCCATGGCCAGCTTGACCTTGAGCACGCTGGCGTTGACGTGGCTGAGCCATTCCGGCTGGTCGGGGTGGCCTTCCAGGCGCAGGCGCGAGACGAAGGTTTCGTAGCCGCCGACGATGACCATCACGAGCAGGTTGGAGATCATGACCACGTCGATCAGGCCCAGCACGATGAGCATGATTTCCTGCTCGCCGAAGGACAGGGTGTGGGTGACCAGGTGCCACAACTCCTTCAGGAAGAGCAGGACGTATACGCCCTGGGCGACGATCAGGCCCAGGTAGAGCGGCAGTTGCAGCCAGCGCGAACTGAAGATCAGCGCGGGCAGAGGGCCGAGGCGGGGTTCTTGGATGGGATGCATGGGAGGTTTGCGAGCCATGGTTGTGTGGAGAATTCGGGCGGGCGAAATTCTACCGTCCCCGGATGCGCCGTGCGCGGCCCGTCGCGGCTGCTCGCCGGGCGCTTCCCGGGGCGCTCCGGTCCCCGGCGAGTTTCCGGTAAAATGATCTGTTTATCCGCTATATCATCTCCCTCTTTCTCGGAAAATAGGTCTCTTAATGCAGCCTGTGGTTGAAACCCTCTCCGGCCTGGAGCGCCGTGTTGATCTGGCCGTCTCGGTCGCCGAAGTCGAAAAGGAAGTCCAGGCGCAATTGAAGCGCGTGGGCCGCACGGCCAAGGTCGCCGGCTTTCGTCCCGGCAAGGCGCCGCTGGCGATGCTCGAGCGCAGCCATGGCCCCGGCATCCGCTACGACGTGATCAACAGTCTGGTCGGCCGCGCTTTCGAACAAGCCGTCGACGGCGCCAAGCTGCGCGTCGCCGGTTCGCCCACCCTCACTCCCAAGACCGAAGGCGTCGCCGAGGACACGCTGGCGTTCACCGCCACGTTCGAGGTGTACCCGGAAGTCACCGTGCCGGACCTGTCGGCGCTGGCCGTCACCCGCTACGACACCCCGGTCACCGACGCCGAAGTCAACCAGACGCTCGACGTGCTGCGCAAGCAACGCGCCAAGTTCGAAACCCGCGAAGGCCGCGCCTCGCAGGACGGCGACCGCGTCGTGCTGGACTTTGCCGGCACGATCGACGGCGTGCCCTTCGAAGGCGGCAAGGCCGAGGACTTCCCGTTCGTGCTGGGCCAGGGCCGCATGCTGCCCGAATTCGAGGAAGCCGCGCTCGGCCTGAAGGCCGGCGAGAGCAAGGTGTTCCCGCTCAAGTTCCCTGACGACTACCAGGGCAAGGAAGTCGCCGGCAAGACGGCCGAGTTCACCATCACCGTCAAGGAAGTCGCCGAAGGCGTGCTGCCCGAGGTCGATGCCGAATTCGCCAAGTCGCTCGGCCAGGCCGAAGGTGATGTCGAAAAGCTGAAGGCCGACATCCGGACCAACATCGAACGCGAAGTCAAGGCGCGCCTGCAAGGCCGCACCAAGGGCAGCGTGATGGATGCGCTGGTCGAGGCCGGCAAGTTCGACGTGCCCAAGGCGCTGGTCGACAGCGACGTGGAAGGCCGTATCGCCGCTGCCCGCGAAGAGCTCAAGCAGCGCGGCGTGCCCAATGCCGATTCCGTGCCGATGCCGGCCGAGGTGTTCTCGACCGAGTCCGAGCGCCGTGTGCGCCTGGGGCTGCTGGTCTCCGAACTGGTCAAGCAGGCCCAGCTGCAGGCCAAGCCCGAGCAGGTGCGCGCGCGCATTGAGGAGTTCGCGCAGAATTACGAACAGCCGGCCCAGGTCGTCAGCTACTACCTGGCCGACCGCCAGCGCCGCGCTGAAATCGAGGCGATCGTGCTCGAGGATAACGTGGTCGCCCACGTGCTCGAGAACGCCAAGGTCGCCGACGAGAAGGTGCCTTTTGATCAGTTGATGGGGATGGCATAACCATGCAGCGTTTCACCGATTTCTATGCGGCAATGCACGGCGGGTCGTCGGTGACGCCCACCGGCCTGGGCTACATCCCGATGGTCATCGAGCAATCGGGCCGGGGCGAGCGTGCCTATGACATTTACTCGCGGCTGTTGCGTGAGCGCCTGATCTTCCTGGTCGGGCCGGTCAACGACAACACGGCCAACCTGGTCGTGGCCCAGTTGCTGTTCCTGGAATCGGAGAACCCCGACAAGGACATCTCGTTCTACATCAACTCGCCCGGCGGGTCGGTGTACGCGGGCATGGCCATCTACGACACCATGCAGTTCATCAAGCCCGATGTGTCGACGCTGTGCACCGGGCTGGCCGCCAGCATGGGCGCATTCCTGCTGGCGGCGGGGAAGAAGGGCAAGCGGTTCACGCTGCCCAATTCCCGCATCATGATTCACCAGCCCTCGGGCGGCGCCCAGGGGCAGGCCAGCGATATCCAGATCCAGGCGCGCGAAATCCTGGATCTGCGCGAGCGCCTGAACCGCATCCTGGCCGAGAATACCGGCCAGCCGGTCGAGCGCATCGCGGTAGACACCGAGCGTGACAACTTCATGTCCGCCGAAGATGCGGTATCGTATGGTCTGGTGGACAAGGTTCTGACCTCTCGCGCGCAGACCTGATCGGCGCGCTTGCAGGACCCTGGCACTGCCGTCATGTTCGATAAGCGTTGATCGCGCCGGCCCTCATCCGGCTGGCGCGTCTTCACCAGAGATACGAAACACTTATGCCTGAAAAAAAGGGATCGGCAGACGCAAAAGTGCTGCATTGCTCGTTTTGCAACAAGAGCCAGCACGAAGTCCGCAAGCTGATTGCAGGTCCTTCGGTATTCATCTGTGATGAATGCATAGACCTTTGCAACGACATCATCCGCGAGGAAGCGCAGGCTACCGCGCGCGCTGCCATTCGCTCCGAGCTGCCCACCCCGGCCGAAATCAAGACCTTTCTCGACCAGTACGTGATTGGCCAGACCAGCCCCAAGCGCATGCTGGCGGTGGCGGTCTACAACCACTACAAGCGTATCCGCCACGGCGAGATCAAGGGCGACGAAGTCGAGCTCTCCAAGAGCAACATCATGCTGATCGGCCCGACCGGGTCGGGCAAGACGCTGCTGGCGCAGACGCTGGCGCGCATGCTCAACGTGCCGTTCGTCATGGCCGATGCCACGACCCTGACCGAGGCCGGCTACGTCGGCGAGGACGTCGAGAACATCATCCAGAAGCTGTTGCAGAACTGCAACTACGATGTCGAGAAGGCGCAGCGCGCCATCATCTACATTGATGAGATCGACAAGATTTCGCGCAAGTCCGACAACCCGTCGATCACCCGCGACGTATCGGGCGAGGGCGTGCAGCAGGCGCTGCTCAAGCTGATCGAAGGCACGGTCGCTTCGGTGCCCCCGCAGGGCGGCCGCAAGCATCCCAACCAGGACTTCGTCCAGGTCGACACCACCAACATCCTGTTCATCGTCGGCGGCGCCTTCGACGGCCTGGAAAAGGTCATCCGCGACCGCACCGAGAAATCGGGCATCGGGTTTTCGGCGGCGGTGCGCGCCAAGTCCGAGCGCGGCGTGGGCGAGCTCTTCAGCGAGGCCGAGCCCGAGGACTTGATCAAGTTCGGCCTGATCCCCGAACTGGTCGGCCGCCTGCCCGTGGTCGCCACGCTGGACGAGCTGGACGAGGCCGCGCTGGTGCAGATCCTGACCGAACCCAAGAACGCGCTGGTCAAGCAGTTCCAGAAGCTGTTCGCCATGGAAGGCGCGGAACTCGACGTGCGGCCGGATGCGCTGAAGGCGATCTCCCGCAAGGCGCTCAAGCGCAAGACGGGGGCGCGCGGCCTGCGCTCCATCCTGGAGGGCGCGCTGCTGGACACCATGTATGACCTGCCGTCGCAAGGCAACGTCAGCCGCGTGGTGCTCGAGGCCAATGCCGTCGAGGGCGACGGCAAGCCCCTGTTGATCTACGCCGACGAATCCGAAGCCGCCTCTGGCGAGAAGGCCGGGCGTGGCGAGGTCCGTGACGCGGCGGCTTGATCTTCGATCCCGGCCGCCATTGCAAGAAAACCCGTTTGTAACGGGTTTTTTTGCATCTTCCCGCTATCTGGATGCCGAGCGCTTGAATTTTCGGCTATTGTTCCCATATCAGACGTAACCGACGTGGAGACCTGGGTCTGCCCTTGCCCCGTCCCCCATTACGCCGAGTCATACCGAGGAACCCCCCTATGTCTGCCAGTCAGACCCTGTCTTCCGACCCGATTGACCTGCCGTTGTTGCCGCTGCGCGATGTTGTCGTGTTTCCGCACATGGTTATTCCGCTGTTTGTCGGCCGCCCGCGCTCGATCCGCGCGCTGGAGGTGGCGATGGAAGCGGGCAAGAGCATCATGCTGGTGGCGCAGAAGTCCGCCGGCAAGGATGACCCGACTCCCGAGGACGTCTATGAGATCGGCTGCGTGGCGAGCATCCTGCAGATGCTCAAGCTGCCCGACGGCACCGTCAAGGTGCTGGTCGAGGGCACCCAGCGCGCTCGCATCGACAGCATCGAAGACGTCGATTCGCATTTCACCTGCCAGGTGACGCCGATCGAGCCCGATACCCTGCAGGGTTCGGAGACCGAGGCGCTGCGCTGCGCCAGCGTCGCGCAGTTCGAGCAGTATGTGAAGCTGAACAAGAAGATTCCGCCCGAGATCCTGACCTCGCTGGCCGGTATCGACGACGCCGGCCGCCTGGCCGACACCATCGCCGCGCATCTGCCGCTCAAGCTGGAGCAGAAACAGAAGATGCTCGAGGTCGTCGTGACCGCCGAGCGCCTGGAAGGGCTGCTGACCCAGCTGGAAACCGAGATCGACATCCTGCAGGTCGAGAAGCGGATCCGCGGGCGCGTCAAAAAGCAGATGGAGAAAAGCCAGCGCGACTACTACTTGAATGAGCAGGTCAAGGCCATTCAGAAGGAGTTGGGCGAAGGCGAGGAAGGCGCCGACATCGAAGAGCTCGAGAAGAAGATCATCGCCGCGCATATGCCCAAGGAGGCGCGCAAGAAGGCCGATGGCGAGCTCAAGAAACTGAAGCTGATGTCGCCCATGTCGGCGGAAGCGACGGTGGTGCGCAACTACATCGATACGCTGATCAACCTGCCCTGGAAGAGAAAGAGCAAGATCAACAACTCGATCGGCAATGCCGAGCGGGTGCTCGACGACGACCACTACGGGCTGGAAAAGGTCAAGGAACGCATTCTCGAGTACCTTGCCGTGCAACAGCGCGTGGACAAGGTCAAGGCGCCGATCCTGTGCCTGGTGGGCCCCCCGGGCGTGGGCAAGACCTCGCTCGGCCAGTCGATCGCCAAGGCGACCAACCGCAAGTTCGTGCGCATGGCGCTGGGCGGCGTGCGCGACGAGGCCGAGATCCGTGGCCACCGCCGTACCTATATCGGTTCGATGCCGGGCAAGATCCTGCAGAACATGTCCAAGGTCGGCGTGCGCAATCCGTTGTTCCTGCTGGACGAGATCGACAAGCTGGGCATGGACTTCCGTGGCGATCCGTCGTCGGCGCTGCTCGAGGTGCTGGATCCGGAGCAGAACCACACGTTCCAGGACCACTACATCGAGGTCGACTTCGACCTGTCCGATGTGATGTTCGTAGCCACCAGCAATACCTTGAACATCCCGCCGGCCCTGCTGGACCGGATGGAAGTGATCCGCCTGTCCGGCTACACCGAGGAAGAGAAGATCCACATTGCTCGCGACCACTTGCTGCCGAAGCTGATGAAGAACAACGGCGTCAAGGACAACGAGCTGACGGTGGACGATTCCGCGCTGCGCGATATCGTGCGCTACTACACCCGCGAGGCGGGCGTTCGGGCGCTGGAGCGCGAGGTCGGCAAGATCTGTCGCAAGGTCGTCAAGCAACTGCTGATCAAGAGCGATGAAGCCAAGGCGGCCGGCAACAAGACCGCCGAGGCGCAAACGGTGCTGGTCAACGGCGACAACCTCAACGATTTCCTGGGCGTGCGCCGCTATACCTTCGGCATGGCCGAAAAGGAAAACCAGATCGGCCAGGTGACCGGCCTTGCATGGACCGAAGTGGGCGGCGATCTGCTCACCATCGAAGTCGCGGACATGCCCGGCAAGGGCAATATCCAGCGCACCGGTTCGCTGGGCGACGTCATGAAGGAGTCGGTCGAGGCCGCACGCACCGTGGTGCGTTCGCGGGCGCGCCGGCTGGGGTTCGCCGACAGCGTGTTCGAGAAGCACGACATGCACGTCCACGTGCCCGAGGGCGCCACGCCCAAGGACGGCCCGTCGGCGGGTATCGCCATCACCACCGCCATGGTGTCGGCGCTGTCGCGCATTCCGGTGCGCGCCGACGTCGCCATGACGGGCGAGATCACGCTGCGCGGCGAGGTGTTGCCCATCGGCGGCCTGAAGGAAAAGCTGTTGGCCGCGCATCGTGGCGGTATCAAGACGGTGCTGATTCCCGAGGAGAACGTCAAGGATCTGGCCGAGATTCCGGATAACGTGAAGAACTTCCTGGAGATCGTTCCGGTGCGCTGGATCGACAAGGTGCTGGAGCTTGCGCTGGAGCGCATGCCCGAGCCGCTGTCCGAGGAAGAAGCCGTCAAGGAAGCCATCGTGGCCAAGCCCGCGGAGGCCGGCGCCGCCGATCCGGTCATGAAGCACTGAGCCGACGCCGGCTCAGGCCGGTGGCCAGCGACCCGCAAAACCGGGCCCGGATCATCCGGGCCCGGTTTTTTTTTTGGTTCATCGCGCAATAGCGTGGAGGGGTTTGGCAAGTTTTCGTATTCTTGACGGCAGGTATTTGCCATCAGGAGTGCAGGGAGATGCTGGATCGCAAGTTGCTGGAGTCGCTGGGAGGCTGGCAGGGCTATGGCGTCGAACGCGTGGAATGGCCCGAAGACCCAGGGCGCACGCTGTCGATCTATTTGAAGCCAACGGCCAAGGTGATGCTGTGCGAGCAGTGCGGCGCGCGGTGTCGCCAGGTGCATGAGACCACGGTTCGACGGGTGCGAGATCTGCCGTTATTCGAGTATCGGGTCGTTCTGCACGTGCCGCGCCGACGCTTGTGGTGTGAGCAATGCGGCGGCCCGCGCCTGGAGCGGCTTGCCTGGCTGGGGCGATATCAACGGGTGACGGATCGGCTGGCGCAGGCCTGCAGCCAATTGCTGCAATCGAGCAACGTGCAGGCGGTGGCGAGGTTCTTCGAGCTGGGTTGGCATACCGTCAAGACGCTGGACAAGGCTCGGCTGCGTGCGTCGGTGCGCGAACCGGATTGGTCCAAGATCGAGTATTTGGCGATGGACGAGTTTGCCCTGCACAAAGGGCATCGCTACGCGACAGTGGTGGTCGATCCGATCGGCAGGCAGGTGCTGTGGATTGGCCCAGGACGCTCACGCGAGACGGCCCGGGCGTTCTTCGAACAATTGCCGCCTGGGGCCGCCCAACGCATCAAGGCCGTTGCCATCGACATGACCACCGCCTACGAGTTGGAGATCCAGGCCCACAGCCCACAGGCGGAGATCGTCTATGACTTGTTCCATGTCGTGGCCAAGTATGGACGAGAGGTCATTGATCGGGTGCGCGTGGATCAGGCCAATCAACTACGCCAGGATCGTCCCGCACGCAGGATCATCAAATCGAGTCGCTGGCTGCTGCTGCGCAACCGTGACAACCTGGATCGGCAGCAGGCCGTCCGGCTCGACGAATTGCTGCAAGCCAACCAGCCGCTGCTGACGGTCTATGTCCTGCGTGACGAACTCAAACGGCTCTGGTTCTACCAAAGACCTGCCTGGGCAAGACAAGCCTGGAACCACTGGTACGAGCAGGCCGAGCAAAGCGGAATACCCGCCTTGAACACCTTCGCTCAGCGCTTGAAAGGCTATCTGCACGGCATCCTGGCCAGATGCCGACATCCCCTGAACACCAGCATTGTCGAGGGCATCAACAACACTATCAAGGTCATCAAGCGGCGCGCTTACGGCTACCGCGACCAGGAATACTTCTTCCTCAAAATCCGTGCCGCCTTCCCCGGCAATGCGCGATGA

Protein sequences of DBSCAN-SWA_5

>NC_018828|2298072:2306530|2302697_2305151_+|WP_015039690.1|DBSCAN-SWA
MSASQTLSSDPIDLPLLPLRDVVVFPHMVIPLFVGRPRSIRALEVAMEAGKSIMLVAQKSAGKDDPTPEDVYEIGCVASILQMLKLPDGTVKVLVEGTQRARIDSIEDVDSHFTCQVTPIEPDTLQGSETEALRCASVAQFEQYVKLNKKIPPEILTSLAGIDDAGRLADTIAAHLPLKLEQKQKMLEVVVTAERLEGLLTQLETEIDILQVEKRIRGRVKKQMEKSQRDYYLNEQVKAIQKELGEGEEGADIEELEKKIIAAHMPKEARKKADGELKKLKLMSPMSAEATVVRNYIDTLINLPWKRKSKINNSIGNAERVLDDDHYGLEKVKERILEYLAVQQRVDKVKAPILCLVGPPGVGKTSLGQSIAKATNRKFVRMALGGVRDEAEIRGHRRTYIGSMPGKILQNMSKVGVRNPLFLLDEIDKLGMDFRGDPSSALLEVLDPEQNHTFQDHYIEVDFDLSDVMFVATSNTLNIPPALLDRMEVIRLSGYTEEEKIHIARDHLLPKLMKNNGVKDNELTVDDSALRDIVRYYTREAGVRALEREVGKICRKVVKQLLIKSDEAKAAGNKTAEAQTVLVNGDNLNDFLGVRRYTFGMAEKENQIGQVTGLAWTEVGGDLLTIEVADMPGKGNIQRTGSLGDVMKESVEAARTVVRSRARRLGFADSVFEKHDMHVHVPEGATPKDGPSAGIAITTAMVSALSRIPVRADVAMTGEITLRGEVLPIGGLKEKLLAAHRGGIKTVLIPEENVKDLAEIPDNVKNFLEIVPVRWIDKVLELALERMPEPLSEEEAVKEAIVAKPAEAGAADPVMKH
>NC_018828|2298072:2306530|2299133_2300444_+|WP_014905723.1|DBSCAN-SWA
MQPVVETLSGLERRVDLAVSVAEVEKEVQAQLKRVGRTAKVAGFRPGKAPLAMLERSHGPGIRYDVINSLVGRAFEQAVDGAKLRVAGSPTLTPKTEGVAEDTLAFTATFEVYPEVTVPDLSALAVTRYDTPVTDAEVNQTLDVLRKQRAKFETREGRASQDGDRVVLDFAGTIDGVPFEGGKAEDFPFVLGQGRMLPEFEEAALGLKAGESKVFPLKFPDDYQGKEVAGKTAEFTITVKEVAEGVLPEVDAEFAKSLGQAEGDVEKLKADIRTNIEREVKARLQGRTKGSVMDALVEAGKFDVPKALVDSDVEGRIAAAREELKQRGVPNADSVPMPAEVFSTESERRVRLGLLVSELVKQAQLQAKPEQVRARIEEFAQNYEQPAQVVSYYLADRQRRAEIEAIVLEDNVVAHVLENAKVADEKVPFDQLMGMA
>NC_018828|2298072:2306530|2305309_2306530_+|WP_015039524.1|transposase|DBSCAN-SWA
MLDRKLLESLGGWQGYGVERVEWPEDPGRTLSIYLKPTAKVMLCEQCGARCRQVHETTVRRVRDLPLFEYRVVLHVPRRRLWCEQCGGPRLERLAWLGRYQRVTDRLAQACSQLLQSSNVQAVARFFELGWHTVKTLDKARLRASVREPDWSKIEYLAMDEFALHKGHRYATVVVDPIGRQVLWIGPGRSRETARAFFEQLPPGAAQRIKAVAIDMTTAYELEIQAHSPQAEIVYDLFHVVAKYGREVIDRVRVDQANQLRQDRPARRIIKSSRWLLLRNRDNLDRQQAVRLDELLQANQPLLTVYVLRDELKRLWFYQRPAWARQAWNHWYEQAEQSGIPALNTFAQRLKGYLHGILARCRHPLNTSIVEGINNTIKVIKRRAYGYRDQEYFFLKIRAAFPGNAR
>NC_018828|2298072:2306530|2301204_2302509_+|WP_010926436.1|protease|DBSCAN-SWA
MPEKKGSADAKVLHCSFCNKSQHEVRKLIAGPSVFICDECIDLCNDIIREEAQATARAAIRSELPTPAEIKTFLDQYVIGQTSPKRMLAVAVYNHYKRIRHGEIKGDEVELSKSNIMLIGPTGSGKTLLAQTLARMLNVPFVMADATTLTEAGYVGEDVENIIQKLLQNCNYDVEKAQRAIIYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPNQDFVQVDTTNILFIVGGAFDGLEKVIRDRTEKSGIGFSAAVRAKSERGVGELFSEAEPEDLIKFGLIPELVGRLPVVATLDELDEAALVQILTEPKNALVKQFQKLFAMEGAELDVRPDALKAISRKALKRKTGARGLRSILEGALLDTMYDLPSQGNVSRVVLEANAVEGDGKPLLIYADESEAASGEKAGRGEVRDAAA
>NC_018828|2298072:2306530|2298072_2298279_+|WP_003812516.1|DBSCAN-SWA
MATGIVKWFNAEKGYGFIMPDDGSKDLFAHYSEIRSEGYKSLQENQRVSFEVGQGPKGPSAKNIKVIA
>NC_018828|2298072:2306530|2298376_2298937_-|WP_033448628.1|DBSCAN-SWA
MHPIQEPRLGPLPALIFSSRWLQLPLYLGLIVAQGVYVLLFLKELWHLVTHTLSFGEQEIMLIVLGLIDVVMISNLLVMVIVGGYETFVSRLRLEGHPDQPEWLSHVNASVLKVKLAMAIIGISSIHLLRTFIEASNLGSPNSRFTETGVMWQTIIHVVFILSAIGIAYVDRLTSQSVGHGAHPSH
>NC_018828|2298072:2306530|2300446_2301100_+|WP_003812508.1|DBSCAN-SWA
MQRFTDFYAAMHGGSSVTPTGLGYIPMVIEQSGRGERAYDIYSRLLRERLIFLVGPVNDNTANLVVAQLLFLESENPDKDISFYINSPGGSVYAGMAIYDTMQFIKPDVSTLCTGLAASMGAFLLAAGKKGKRFTLPNSRIMIHQPSGGAQGQASDIQIQAREILDLRERLNRILAENTGQPVERIAVDTERDNFMSAEDAVSYGLVDKVLTSRAQT

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003812516.1|2298072_2298279_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	8.1e-16	62.1
WP_033448628.1|2298376_2298937_-	TIGR00645 family protein	K4K6D8	Caulobacter_phage	1.0e-23	33.7
WP_014905723.1|2299133_2300444_+	trigger factor	NA	NA	NA	NA
WP_003812508.1|2300446_2301100_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	6.8e-56	57.5
WP_010926436.1|2301204_2302509_+|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	5.4e-129	53.8
WP_015039690.1|2302697_2305151_+	endopeptidase La	A0A0R6PGP8	Moraxella_phage	6.6e-221	52.1
WP_015039524.1|2305309_2306530_+|transposase	ISL3-like element IS1001 family transposase	A4PE56	Ralstonia_virus	8.7e-198	81.3

Sequences of DBSCAN-SWA_6

Nucleotide sequences of DBSCAN-SWA_6

>NC_018828|2975524:2982984|DBSCAN-SWA
GTCATCGCGGCGGCAGATACTGCATCGGGTCGACCGGCGTGCCCTGGCGGCGGATCTCGAAATGCAGGCGCGGCGACGTGGTGTCGGTCTCGCCGATCTCGGCGATCTTGGCCCCGCGCTTGACGTTCTGGCCGGTCTTGACCAGCAGCGCGCGGTTGTGCGCATAGGCCGTGATGAAGCCGTTCTGGTGATTGATGATGATCAGGTTGCCCAGGCCGCGCACGCCATTGCCGCTGTACATCACCTTGCCATCGGCCGCCGCGATCACCGGATCGCCCAGCGAGCCGGCCAGGTCGATGCCCTTGGTGTTGCTGTTGAAGGTCTGCAGGATGGCGCCATTGGCCGGCCAGCCCCAGTTGATGACGGCGGCATCGGCCGCGCGCGCGGGCTTGGGATCGGGCACCGTTGCCGCGGGCGGGGTGGTGGCCCCGCCGGTTTCGCCGCCGGCGCCGGCTTCCATGCCGCCGGCCGGCGTTTCGGCGCTTCCCTGGTCCAGCGGCTTGGGTTGCGGCTTGGAGGAGGTCACCGGCGTGGTCTGCGCGCCGCCGGCGCCCGAGCTCGACAGGCGCAGCACCTGGCCGACACTGATCTGGTTGGGATCGGTGAGGTTGTTCCAGCGCTTGAGGTTTTCGATATCGACATTGTTGGCGCGCGCGATCTTGTAGAGCGTATCGCCAGGCTTGACGACATAGCTGCCGTCGGTCGGGCCGGAGGCGCCGGGCTGTCCGGTGAGGTCGACCACGGGCGCGCGCGAGCCCTTCGAGGCGCAGCCGGCCAGCAAGGCGATGGCCAGCACGCCCGCCCAGAGAACGGGTCGGGAAGCGGCGGCGGCGGATGCGCCAGCCACGGATTGGGATTCGGTCAGTTGCAACTGCCCGTTGAGCATACGATTCTCCTGTTTGCTCAAGATTGTATTCCGGCCCTGAGGGGCACAAAACGTACAGCTTCGAGTTCTTTTCGGCTCCAGGCGGTGGCCCCGGTGCGTTCGATCAGCACCAGCCGCTGGTGGGTGGACCCTTCGGGCGCGATCAGCCGCCCGCCCGGCGCAAGCTGATCCAGCAAGGCCTGCGGAATGGCCAGGCCCGCCGCAGCCACAACAATAGCATCGAACGGCGCCACGCCGGGCACGCCCAGCATGCCGTCGCCATGGATCAGGCGCACCCGGGTGGCCAGGCGCAGCGCCCGCAGATGGCCGCGCGCCAGCTCGTACAGGCCGCGGATGCGCTCGATGGCATGCACCTCGCGCACGATCTGGGCCAGTACCGCCGCCTGGTAGCCGCAGCCGGCGCCAACCTCGAGCACCCGGGCCGGGGCACGGTCCTCGCAGACGGCGGCGATCATGCGGGCCACCACCCACGGCTGCGAAATGGTCTGCGAGTGCCCGATGGGCAGCGCCGCGTCTTCGTAGGCACGGCTGGCCAGCGCTTCATCGACGAACAGATGGCGCGGCACCGCCGCCATGGCGTTGAGCACCCGTTCGTCGACGATGCCCTGCGTGCGCAGCCGCTGCACCATCGCCTGGCGCAGCCGGTCGGAGTTCAGGCCCAGGTTGCCGCTGGCCAGCGGCGCGGGCTGCGCAGGCGCGCGCGGCAAGGCGCCGGCCGAAATGCGGGTGTTGCTGTTGGCCGGCGTGATGCCGGGCGCGAGGCGGCCGCCGGCCGGCGGGTCTACGCGTTTACGCATAGCGGCTCCGCCCAGTTGCGCACATCGTCAAGCTGGCTGTGCTGGGTCAGGTCCAGGCGCAGCGGCGTCACCGAGACCTGCCCCTGCGCCGTGGCGTGGAAGTCCGTCCCCGGCGTGGCGTCGGCGGCCAGGCCGACCGGGCCGATCCAGTACACCGTGTCGCCATAAGGCGTGGTGGTACGCACCACCGGCTCGGACGGATGGCGCTTGCCCAACCGCGTGACGGCGTAGCCTTTCATGTCTTCGTAGCGGCGATTGGGGATATTGACGTTGAGCAGGACCGGCGCGGCCAGCGGCTGCGCGATCTGGCGCTCGACCACCTGGCGGGCGGCGCGCGCGGCCGATTCGATGTGCTGCCAGCCTTTTTCGATCAGCGAGAAGGCGATCGAGGGAATGCCGAACAGGTAGCCCTCGCTGGCCGCGGCCACCGTGCCGGAATAAAGCGTGTCGTCGCCCATGTTGGCGCCATTGTTGATGCCGGACACCACCAGGTCGGGGCGCGCATCCATCAGGCCGGTCAGGGCGACGTGCACGCAATCGGACGGCGTGCCGTTGACGTAGATGAAGCCGTTGGAAGCGGTGCGCACCGTCAGCGGCCGGTTCAGGGTCAGGGAATTCGAGGCGCCGCTGTGATTCGTCTCCGGCGCGACCACGGTCAGTTCGCCCAGCCCGGACAGCGCCTCGACCAGCGCTTCCAGCCCGGGGGCGTTGTAACCATCGTCGTTTGAAACCAGAATACGCATCAATCTTCCTGAATCGTGGGAATCGCCACAAACCGCGACCGATTGTACCGTCATGAAGCGGCATCATCGCGTCAGAATCGCCGCCCGAGGTAGAATCCGCAGCCAAACGACGCAACCGTAACGGAATGCCTGCCACCATGGTCCTGACCGCCCCTTCGCTCCTGTCCAGTTCGGCACTGATTGTCCTGGCCTATCTGATCGGCTCCATCCCCTTTGCCGTCGTGGTCAGCAAGCTGATGGGGCTGCAGGATCCGCGCAGTTACGGCTCCGGCAATCCGGGCGCCACCAATGTGCTGCGCACCGGCAACAAGACCGCCGCCGCGCTGACCCTGCTGGGCGACGCGGCCAAGGGCTGGTTCGCGCTGTGGCTGGCCCGCGCGCTGGTCCCCGAACTCTCCTGGGGCGCCTACGCGCTGGTGGCGCTGGCGGTGTTCCTCGGCCACCTCTACCCCCTGTTCCTGCGCTTCAAGGGCGGCAAGGGCGTCGCCACGGCGCTGGGCGTACTGATGGCCATCGAGCCATGGCTGGCCGTGGCCACCATCGCAACCTGGCTGATCGTGGCCGTGTTCTCGCGCTATTCGTCCCTGGCGGCCCTGGTCGCCGCATTTTTCGCGCCCGTCTACTACGTATTCGGCTCGGGCGCAGCCTGGCATGCGCGGCTGGAAGTCGGCCTGGCCATCGCCGTCATCAGCGCCCTGCTGTTCTACCGCCACCGCGCCAACATCGCGCGGCTGCTCAAGGGCACCGAAAGCCGCATCGGGAAGAAGAAGTAACCCACTCAGGAGCCTGCCCCCGCGGGGACAGGCCCCCCGTCAGCCTACCCGGCCTGGATATCCGCCAGGTCCCAGCGCGGCCGCACCGTGAAGGCGTGGTCGCCCTCGCGCAGGTCGGCCAGTCCGGCCTTGACCCGCTCGGCCGCCGCGAACGCGATCATGGCGCCATTGTCGGTGCACAGCGACAGCGGCGGAAAATAGGCTTCGGCCCGCAAGGGCTTGAGCGCGCGCGCCAGATGCGCGCGCAGCAGCGCGTTGGCGCCCACCCCGCCGGCCACCACCAGGCGGCGCAGGCCCGTCTGCTTCAAGGCGCGGATCGCCTTGGCCGCCAGCACCTCGACGATGGCGGCCTGCGTTGCCGCCGCCAGGTCGGCGCGGTCCTGTTCGCCCAGTTCGCCGCCATCGCGCGTGGCCGCTTTCACACGGGTCAGGACCGCGGTCTTCAATCCGCTGAAGCTGAAATCCAGGTCGCCGCTGTGCAGCATGGGGCGCGGCAGGTCGTAGCGGCTGGCGTCGCCCTGCTCGGCCAGGCGCGCCAGCGCGGGGCCGCCCGGATAGCCCAGGCCCATCAGTTTGGCCGATTTGTCGAAGGCCTCGCCGGCGGCGTCGTCCAGCGTCTCGCCCAGCAGTTCGTAGCGGCCCACGCCGTCGACCCGCATCAGCTGGGTATGCCCGCCCGAGACCAGCAAGGCCACGAACGGAAACTCGGGACGCGGCTCGGCCAGCAGCGGCGACAGCAGATGTCCTTCCAGGTGATGGATGCCGATGGCCGGCAGCGCGCGCGACCAGGCCAGCGCCTGGGCCACGCTGGCGCCCACCAGCAAGGCGCCGGCCAGGCCCGGCCCGGCGGTGTAGGCCACCGCGCCCACGTCGGCCAGCGTCAGGCCGGCCTCGGCCAGCACCTGGCGGGTCAGGGGCACCACGCGCCGGATATGGTCGCGCGAGGCGAGTTCGGGCACCACGCCACCATATTCCTGGTGCATGGCGATCTGGGTATGCAGGGCGTGCGCAAGCAGGCCGCGCTCGGTGCAGACGGCGGCCACGCCGGTTTCGTCGCACGAGCTTTCAAAGCCGAGAATGATCATGGGCGCAGAGTTTACAACCAGGGTCCGCGGGCCCTGGTGCAAAAATACGGGTTTTGCGCTTACATTATCGCCTGCGCGGCAGGCGGCGCCGGCGCAAGCACACAACAACCGCTCTCAAACCCCCGGGGACTTCCATGCTGGAGAAGCTATTCCAACTGCGTGACCACGCCACGACCGTACGCACGGAGATCGTGGCTGGGCTGACGACATTCCTCACCATGTCGTACATCATCTTCCTGAACCCCGACATCCTGTCGAGCACCGGCATGGATCGCAATGCCGTGTTCGTGGCGACCTGCCTGGCCGCCGCCCTGGGTTCGCTGATCATGGCGCTGGTGGCCAACTGGCCGATCGGCATGGCGCCGGGCATGGGCCTGAACGCGTTCTTCGCGTTCACCGTGGTCAAGACCATGGGCTACACCTGGGAGCAGGCGCTGGGCGCCGTGTTCATCTCGGGCGTCATCTTCCTGTTCCTGACCATCTCGGGCATCCGCGCCTGGCTCATCCGCGGCATCCCGCACTCGCTGCGCAGCGCCATCGCCGCCGGGATCGGGCTGTTCCTGGCCATCATCGCGCTGTCCAACGCCAACATCGTCGTCGCGCACCCCGCCACCAAGGTGACGCTGGGCGACCTGCGCGAGCCCGGCCCGCTGTTCGCCATCCTGGGCTTTTTCATCATCGCGGCGCTGGATGCGCTGCGCGTGCGCGGCGCGATCCTGATCGGCATCCTGTCGGTGACCGTGCTGTCCATGCTGCTGGGCTACAACCAGTTCAACGGCATCTTCTCCTCGCCGCCCAGCCTGGCCCCGACGTTCATGCAACTGGACATCCTGGGCGCCCTGCACACCGGCTTCGTGCACGTGATCCTGGTGTTCGTGCTGGTCGAGGTGTTCGACGCCACCGGCACGCTGATGGGCATCGCCAAGCGCGCCGGCCTGGTGCCGGAAGACCGCCCCAACCGCCTGGGACGCGCGCTGTTTGCCGACAGCACCGCCATCGTGGCCGGCTCGATGCTGGGCACCAGCAGCACCACCGCCTATGTGGAAAGCGCCTCGGGCGTACAGGCGGGCGGACGCACCGGCCTGACGGCGCTGGTCGTGGCGCTGCTGTTCCTGGCCGCGCTGTTCATCGCGCCGCTGGCCGGCTCGGTGCCCGCCTACGCCACCGCGCCCGCGCTGCTGTATGTCGCCGGGCTGATGATGCGCGAGCTGATCGACATCGACTGGAACGACGTGTCCGAGGCCACGCCGGCCGCGCTGACCGCCCTGGTCATGCCGTTCACGTACTCCATCGCCAACGGCCTGGCCTTCGGCTTCATCAGCTACGTGGTGCTCAAGACCTGCACCGGCCGCATCCGCGAGGTGCACCCGGCCACCTGGCTGGTGGCGATCCTGTTCATCGTCCGCTACGCCTTCTTCCCCGAATAAGGCCAGGCCGCGCGCCTCGCCCCGCAAGCAGGCCGCCTCGCGCGGCCTGCCTGCTTTCGAGGCCTTCAATCGCCGCGATACAGCGAGACTATCGACCCGATGGCGCCCAAGGTTGTTCGGGTGCGCGGTTGAAATCGCCGATACACTCTCCATATATTCCTGACCCGTCGGGCGCGCCGCGCCGCGACACAACCGGAGCACCCGCATGAGTGTATTGGCCAGCGTGCCGTTCTCGGTCCTCGACCTTGCCCCCATCGTGCAGGGCGGCACGGCCGCGCAGGCGTTTCGCAACACCGTCGACCTGGCGCGCCACGTCGAAGGCTGGGGCTATCGCCGCTTCTGGCTGGCCGAACACCACAACATCACCGGCGTGGCCAGCAGCGCCACGGCGGTACTGATCGGCCACGTCGCCGCGCATACCAGCACGCTGCGGGTGGGCTCGGGCGGCGTGATGCTGCCCAACCACGCGCCGCTCATCATCGCCGAGCAGTTCGGCACCCTGGAGAGCCTGTTTCCCGGCCGCATCGACCTGGGCCTGGGCCGCGCGCCCGGCAGCGACGGGGCCACCCAGCAGGCGCTGCGGCGCGGGCCGCGCAGCGGCCTGGACTTTCCCGAACTGCTGCACGAGCTGCGCGCGTACCTCGCGCCGGCGCGGCCGGGCCAGCCGGTGCGCGCGATTCCCGGCGCCGGCACCGACGTGCCCATCTGGCTGCTGGGCTCGAGCGATTTCAGCGCGCGGCTGGCCGCCGAGCTGGGCCTGCCCTTCTCGTTCGCGGGCCACTTCTCGCCCGAAGGCATGGCCGCCATGCGCCTGTATCGGCAACTGTTCAAGCCGTCGCAGACGCTGGCGCGCCCCCATGCCATGATAGGCGTGCCGGTGGTGGCGGCCGACACCGACGAGCAGGCGCATTTCCTGTCCACCACCCAGCAACTGAAATTCCTGTCGCTGATCCGCGGCAACCGCCTGCCGCTGCAGCCGCCCGTGGAAAGCATGGACGGCATATGGAACGAGTGGGAGCGCTCCGCAGTCCAACAGAGACTGGGCGCGGCCATCGTTGGCGGCCCCGATACGGTCAAGCGCGAACTGGAGAGCCTGGTCGCGCAGACCCAGGCCGACGAGGTGATGATCGTTTCCGATTTTTACGACTTTTCCGATCGGCTGCGTTCGTACGAGATCGTCGCCTCGCTCAAGCAGGACGCAGGCGTATCGACCCGCACCGCGAACGCCTGACCGGCACGGCGCGCGATCGCGCCACGCGTTTCGCCCACCGACCACGGACGGAACATCCACTGCGCGGCCCCGGCCGCGCCAACCGGGCCCACGGGCCCCAGACGCCACCCTACGCGGGCGGCAAGGACGACACGCATGAGCATCGTTGAACTGACCAAGGACACCTTCCAGGACGCCATCACGCCCGACGGCACCCTAATCATCGACTTCTGGGCCCCCTGGTGTGGCCCGTGCCGCGGCTTCGCCCCCGTGTTCGAGCAGGCGGCCGAGCAACACCCCGACGTGACCTTCGCCAAGGTCAATACCGACGTCGAACAGGAGCTGGCCGGCGCGCTGGGCATCCGCTCGATCCCGACCTTGATGGTGTTTCGCGAGAAGGTCCTGCTGTTCTCGCAACCCGGCGCCCTGTCGGCCGGCCAGCTCGGCGAGCTGCTGACCAAGGTCAAGGAAGTTGACATGGCCGAGGTGCACCGCGATATCGCGCAGGCGCGCGAAAACGGCGAAGGCGAACAGGCCTGA

Protein sequences of DBSCAN-SWA_6

>NC_018828|2975524:2982984|2975524_2976409_-|WP_015039995.1|DBSCAN-SWA
MLNGQLQLTESQSVAGASAAAASRPVLWAGVLAIALLAGCASKGSRAPVVDLTGQPGASGPTDGSYVVKPGDTLYKIARANNVDIENLKRWNNLTDPNQISVGQVLRLSSSGAGGAQTTPVTSSKPQPKPLDQGSAETPAGGMEAGAGGETGGATTPPAATVPDPKPARAADAAVINWGWPANGAILQTFNSNTKGIDLAGSLGDPVIAAADGKVMYSGNGVRGLGNLIIINHQNGFITAYAHNRALLVKTGQNVKRGAKIAEIGETDTTSPRLHFEIRRQGTPVDPMQYLPPR
>NC_018828|2975524:2982984|2979941_2981234_+|WP_003811011.1|DBSCAN-SWA
MLEKLFQLRDHATTVRTEIVAGLTTFLTMSYIIFLNPDILSSTGMDRNAVFVATCLAAALGSLIMALVANWPIGMAPGMGLNAFFAFTVVKTMGYTWEQALGAVFISGVIFLFLTISGIRAWLIRGIPHSLRSAIAAGIGLFLAIIALSNANIVVAHPATKVTLGDLREPGPLFAILGFFIIAALDALRVRGAILIGILSVTVLSMLLGYNQFNGIFSSPPSLAPTFMQLDILGALHTGFVHVILVFVLVEVFDATGTLMGIAKRAGLVPEDRPNRLGRALFADSTAIVAGSMLGTSSTTAYVESASGVQAGGRTGLTALVVALLFLAALFIAPLAGSVPAYATAPALLYVAGLMMRELIDIDWNDVSEATPAALTALVMPFTYSIANGLAFGFISYVVLKTCTGRIREVHPATWLVAILFIVRYAFFPE
>NC_018828|2975524:2982984|2978086_2978722_+|WP_023852762.1|DBSCAN-SWA
MVLTAPSLLSSSALIVLAYLIGSIPFAVVVSKLMGLQDPRSYGSGNPGATNVLRTGNKTAAALTLLGDAAKGWFALWLARALVPELSWGAYALVALAVFLGHLYPLFLRFKGGKGVATALGVLMAIEPWLAVATIATWLIVAVFSRYSSLAALVAAFFAPVYYVFGSGAAWHARLEVGLAIAVISALLFYRHRANIARLLKGTESRIGKKK
>NC_018828|2975524:2982984|2976426_2977206_-|WP_010928874.1|DBSCAN-SWA
MRKRVDPPAGGRLAPGITPANSNTRISAGALPRAPAQPAPLASGNLGLNSDRLRQAMVQRLRTQGIVDERVLNAMAAVPRHLFVDEALASRAYEDAALPIGHSQTISQPWVVARMIAAVCEDRAPARVLEVGAGCGYQAAVLAQIVREVHAIERIRGLYELARGHLRALRLATRVRLIHGDGMLGVPGVAPFDAIVVAAAGLAIPQALLDQLAPGGRLIAPEGSTHQRLVLIERTGATAWSRKELEAVRFVPLRAGIQS
>NC_018828|2975524:2982984|2978766_2979807_-|WP_003811013.1|tRNA|DBSCAN-SWA
MIILGFESSCDETGVAAVCTERGLLAHALHTQIAMHQEYGGVVPELASRDHIRRVVPLTRQVLAEAGLTLADVGAVAYTAGPGLAGALLVGASVAQALAWSRALPAIGIHHLEGHLLSPLLAEPRPEFPFVALLVSGGHTQLMRVDGVGRYELLGETLDDAAGEAFDKSAKLMGLGYPGGPALARLAEQGDASRYDLPRPMLHSGDLDFSFSGLKTAVLTRVKAATRDGGELGEQDRADLAAATQAAIVEVLAAKAIRALKQTGLRRLVVAGGVGANALLRAHLARALKPLRAEAYFPPLSLCTDNGAMIAFAAAERVKAGLADLREGDHAFTVRPRWDLADIQAG
>NC_018828|2975524:2982984|2977190_2977949_-|WP_003811017.1|DBSCAN-SWA
MRILVSNDDGYNAPGLEALVEALSGLGELTVVAPETNHSGASNSLTLNRPLTVRTASNGFIYVNGTPSDCVHVALTGLMDARPDLVVSGINNGANMGDDTLYSGTVAAASEGYLFGIPSIAFSLIEKGWQHIESAARAARQVVERQIAQPLAAPVLLNVNIPNRRYEDMKGYAVTRLGKRHPSEPVVRTTTPYGDTVYWIGPVGLAADATPGTDFHATAQGQVSVTPLRLDLTQHSQLDDVRNWAEPLCVNA
>NC_018828|2975524:2982984|2981439_2982465_+|WP_003811009.1|DBSCAN-SWA
MSVLASVPFSVLDLAPIVQGGTAAQAFRNTVDLARHVEGWGYRRFWLAEHHNITGVASSATAVLIGHVAAHTSTLRVGSGGVMLPNHAPLIIAEQFGTLESLFPGRIDLGLGRAPGSDGATQQALRRGPRSGLDFPELLHELRAYLAPARPGQPVRAIPGAGTDVPIWLLGSSDFSARLAAELGLPFSFAGHFSPEGMAAMRLYRQLFKPSQTLARPHAMIGVPVVAADTDEQAHFLSTTQQLKFLSLIRGNRLPLQPPVESMDGIWNEWERSAVQQRLGAAIVGGPDTVKRELESLVAQTQADEVMIVSDFYDFSDRLRSYEIVASLKQDAGVSTRTANA
>NC_018828|2975524:2982984|2982600_2982984_+|WP_003811007.1|DBSCAN-SWA
MSIVELTKDTFQDAITPDGTLIIDFWAPWCGPCRGFAPVFEQAAEQHPDVTFAKVNTDVEQELAGALGIRSIPTLMVFREKVLLFSQPGALSAGQLGELLTKVKEVDMAEVHRDIAQARENGEGEQA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015039995.1|2975524_2976409_-	peptidoglycan DD-metalloendopeptidase family protein	A0A292GJG6	Xanthomonas_phage	4.6e-15	49.5
WP_010928874.1|2976426_2977206_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	4.8e-32	46.9
WP_003811017.1|2977190_2977949_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	6.2e-69	51.2
WP_023852762.1|2978086_2978722_+	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_003811013.1|2978766_2979807_-|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	9.3e-92	51.6
WP_003811011.1|2979941_2981234_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	1.7e-66	36.0
WP_003811009.1|2981439_2982465_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_003811007.1|2982600_2982984_+	thioredoxin family protein	V9SJ74	Achromobacter_phage	8.1e-09	25.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage
NC_018828.1|WP_015039442.1|1756931_1757147_+|hypothetical-protein	1756931_1757147_+	71 aa aa	NA	NA	NA	1715779-1774980	yes
NC_018828.1|WP_164926499.1|1757106_1757289_-|hypothetical-protein	1757106_1757289_-	60 aa aa	NA	NA	NA	1715779-1774980	yes
NC_018828.1|WP_015039444.1|1757655_1758030_+|hypothetical-protein	1757655_1758030_+	124 aa aa	NA	NA	NA	1715779-1774980	yes

Protein sequences of NC_018828.1|WP_015039442.1|1756931_1757147_+|hypothetical-protein

>NC_018828.1|WP_015039442.1|1756931_1757147_+|hypothetical-protein
MVNPIEPGVIPHEFQRDVIAAAIKSAAFALRQSREADPAKAARQVAEAAVVAWEVVNGLSRSASPSPRTAG

Self-targetings in the prophage

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751160-1751189	0
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751160-1751189	1
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751388-1751417	0
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751388-1751417	1
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751172-1751201	1
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751172-1751201	0
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751304-1751333	1
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751304-1751333	2
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751316-1751345	1
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751316-1751345	0
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751040-1751069	2
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751052-1751081	2
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751328-1751357	2
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751328-1751357	1
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751340-1751369	2
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751340-1751369	1
NC_018828_4	Orphan	4.2|2259121|54|NC_018828|CRT	2259121-2259174	54	1751220-1751273	0
NC_018828_4	Orphan	4.2|2259121|54|NC_018828|CRT	2259121-2259174	54	1751088-1751141	2
NC_018828_4	Orphan	4.3|2259193|66|NC_018828|CRT	2259193-2259258	66	1751376-1751441	8
NC_018828_4	Orphan	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	1751256-1751297	0
NC_018828_4	Orphan	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	1751076-1751117	1
NC_018828_4	Orphan	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	1751112-1751153	1
NC_018828_4	Orphan	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	1751208-1751249	1
NC_018828_4	Orphan	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	1751232-1751273	1
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751184-1751213	2
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751364-1751381	0
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751412-1751429	0
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751064-1751081	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751076-1751093	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751112-1751129	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751196-1751213	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751208-1751225	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751256-1751273	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751280-1751297	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751448-1751465	1
NC_018828_4	Orphan	4.7|2259421|42|NC_018828|CRT	2259421-2259462	42	1751400-1751441	0
NC_018828_4	Orphan	4.7|2259421|42|NC_018828|CRT	2259421-2259462	42	1751184-1751225	2
NC_018828_4	Orphan	4.7|2259421|42|NC_018828|CRT	2259421-2259462	42	1751352-1751393	2

1. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751160-1751189, mismatch: 0

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

2. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751160-1751189, mismatch: 1

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

3. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751388-1751417, mismatch: 0

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

4. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751388-1751417, mismatch: 1

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

5. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751172-1751201, mismatch: 1

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

6. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751172-1751201, mismatch: 0

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

7. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751304-1751333, mismatch: 1

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtaccaggcagcgtcccaggc	Protospacer
*********** ******************

8. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751304-1751333, mismatch: 2

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtaccaggcagcgtcccaggc	Protospacer
** ******** ******************

9. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751316-1751345, mismatch: 1

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

10. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751316-1751345, mismatch: 0

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

11. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751040-1751069, mismatch: 2

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcggccctggcagcgtcccaggc	Protospacer
********** *** ***************

12. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751052-1751081, mismatch: 2

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcggccctggc	Protospacer
********************** *** ***

13. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751328-1751357, mismatch: 2

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcggcccaggc	Protospacer
** ******************* *******

14. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751328-1751357, mismatch: 1

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcggcccaggc	Protospacer
********************** *******

15. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751340-1751369, mismatch: 2

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcggcccaggcagcgtcccaggc	Protospacer
** ******* *******************

16. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751340-1751369, mismatch: 1

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcggcccaggcagcgtcccaggc	Protospacer
********** *******************

17. spacer 4.2|2259121|54|NC_018828|CRT matches to NC_018828 position: 1751220-1751273, mismatch: 0

actggcagcggccctggcagcggccctggcagcggccctggcagcggcactggc	CRISPR spacer
actggcagcggccctggcagcggccctggcagcggccctggcagcggcactggc	Protospacer
******************************************************

18. spacer 4.2|2259121|54|NC_018828|CRT matches to NC_018828 position: 1751088-1751141, mismatch: 2

actggcagcggccctggcagcggccctggcagcggccctggcagcggcactggc	CRISPR spacer
actggcagcggccctggcagcggccctggcagcggcactggcagcggccctggc	Protospacer
************************************ *********** *****

19. spacer 4.3|2259193|66|NC_018828|CRT matches to NC_018828 position: 1751376-1751441, mismatch: 8

actggcagcggccctggcagcgtcccaggcagcgtcccaggcagcggccctggcagcggc	CRISPR spacer
actggcagcggccctggcagcgtcccaggcagcgtcccaggcagcggcactggcatcggc	Protospacer
************************************************ ****** ****

20. spacer 4.4|2259277|42|NC_018828|CRT matches to NC_018828 position: 1751256-1751297, mismatch: 0

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggcactggcagcggccctggcagcggcactggc	Protospacer
******************************************

21. spacer 4.4|2259277|42|NC_018828|CRT matches to NC_018828 position: 1751076-1751117, mismatch: 1

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggcactggcagcggccctggcagcggccctggc	Protospacer
************************************ *****

22. spacer 4.4|2259277|42|NC_018828|CRT matches to NC_018828 position: 1751112-1751153, mismatch: 1

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggcactggcagcggccctggcatcggcactggc	Protospacer
******************************* **********

23. spacer 4.4|2259277|42|NC_018828|CRT matches to NC_018828 position: 1751208-1751249, mismatch: 1

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggcactggcagcggccctggcagcggccctggc	Protospacer
************************************ *****

24. spacer 4.4|2259277|42|NC_018828|CRT matches to NC_018828 position: 1751232-1751273, mismatch: 1

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggccctggcagcggccctggcagcggcactggc	Protospacer
************ *****************************

25. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751184-1751213, mismatch: 2

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcggccctggc	Protospacer
********************** *** ***

26. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751364-1751381, mismatch: 0

ccaggcagcggcactggc	CRISPR spacer
ccaggcagcggcactggc	Protospacer
******************

27. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751412-1751429, mismatch: 0

ccaggcagcggcactggc	CRISPR spacer
ccaggcagcggcactggc	Protospacer
******************

28. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751064-1751081, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
ccaggcagcggccctggc	Protospacer
************ *****

29. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751076-1751093, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

30. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751112-1751129, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

31. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751196-1751213, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
ccaggcagcggccctggc	Protospacer
************ *****

32. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751208-1751225, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

33. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751256-1751273, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

34. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751280-1751297, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

35. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751448-1751465, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

36. spacer 4.7|2259421|42|NC_018828|CRT matches to NC_018828 position: 1751400-1751441, mismatch: 0

ccaggcagcgtcccaggcagcggcactggcatcggcactggc	CRISPR spacer
ccaggcagcgtcccaggcagcggcactggcatcggcactggc	Protospacer
******************************************

37. spacer 4.7|2259421|42|NC_018828|CRT matches to NC_018828 position: 1751184-1751225, mismatch: 2

ccaggcagcgtcccaggcagcggcactggcatcggcactggc	CRISPR spacer
ccaggcagcgtcccaggcagcggccctggcagcggcactggc	Protospacer
************************ ****** **********

38. spacer 4.7|2259421|42|NC_018828|CRT matches to NC_018828 position: 1751352-1751393, mismatch: 2

ccaggcagcgtcccaggcagcggcactggcatcggcactggc	CRISPR spacer
ccaggcagcgtcccaggcagcggcactggcagcggccctggc	Protospacer
******************************* **** *****

Protein sequences of NC_018828.1|WP_164926499.1|1757106_1757289_-|hypothetical-protein

>NC_018828.1|WP_164926499.1|1757106_1757289_-|hypothetical-protein
MDRSQYHHCANLFVEIAKAQPALIQSSGHGALAGKRLAEMAWAFIDEFNRQYEEKVTPND

Self-targetings in the prophage

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751160-1751189	0
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751160-1751189	1
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751388-1751417	0
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751388-1751417	1
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751172-1751201	1
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751172-1751201	0
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751304-1751333	1
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751304-1751333	2
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751316-1751345	1
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751316-1751345	0
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751040-1751069	2
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751052-1751081	2
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751328-1751357	2
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751328-1751357	1
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751340-1751369	2
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751340-1751369	1
NC_018828_4	Orphan	4.2|2259121|54|NC_018828|CRT	2259121-2259174	54	1751220-1751273	0
NC_018828_4	Orphan	4.2|2259121|54|NC_018828|CRT	2259121-2259174	54	1751088-1751141	2
NC_018828_4	Orphan	4.3|2259193|66|NC_018828|CRT	2259193-2259258	66	1751376-1751441	8
NC_018828_4	Orphan	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	1751256-1751297	0
NC_018828_4	Orphan	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	1751076-1751117	1
NC_018828_4	Orphan	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	1751112-1751153	1
NC_018828_4	Orphan	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	1751208-1751249	1
NC_018828_4	Orphan	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	1751232-1751273	1
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751184-1751213	2
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751364-1751381	0
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751412-1751429	0
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751064-1751081	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751076-1751093	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751112-1751129	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751196-1751213	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751208-1751225	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751256-1751273	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751280-1751297	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751448-1751465	1
NC_018828_4	Orphan	4.7|2259421|42|NC_018828|CRT	2259421-2259462	42	1751400-1751441	0
NC_018828_4	Orphan	4.7|2259421|42|NC_018828|CRT	2259421-2259462	42	1751184-1751225	2
NC_018828_4	Orphan	4.7|2259421|42|NC_018828|CRT	2259421-2259462	42	1751352-1751393	2

1. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751160-1751189, mismatch: 0

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

2. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751160-1751189, mismatch: 1

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

3. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751388-1751417, mismatch: 0

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

4. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751388-1751417, mismatch: 1

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

5. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751172-1751201, mismatch: 1

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

6. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751172-1751201, mismatch: 0

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

7. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751304-1751333, mismatch: 1

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtaccaggcagcgtcccaggc	Protospacer
*********** ******************

8. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751304-1751333, mismatch: 2

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtaccaggcagcgtcccaggc	Protospacer
** ******** ******************

9. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751316-1751345, mismatch: 1

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

10. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751316-1751345, mismatch: 0

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

11. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751040-1751069, mismatch: 2

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcggccctggcagcgtcccaggc	Protospacer
********** *** ***************

12. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751052-1751081, mismatch: 2

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcggccctggc	Protospacer
********************** *** ***

13. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751328-1751357, mismatch: 2

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcggcccaggc	Protospacer
** ******************* *******

14. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751328-1751357, mismatch: 1

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcggcccaggc	Protospacer
********************** *******

15. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751340-1751369, mismatch: 2

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcggcccaggcagcgtcccaggc	Protospacer
** ******* *******************

16. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751340-1751369, mismatch: 1

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcggcccaggcagcgtcccaggc	Protospacer
********** *******************

17. spacer 4.2|2259121|54|NC_018828|CRT matches to NC_018828 position: 1751220-1751273, mismatch: 0

actggcagcggccctggcagcggccctggcagcggccctggcagcggcactggc	CRISPR spacer
actggcagcggccctggcagcggccctggcagcggccctggcagcggcactggc	Protospacer
******************************************************

18. spacer 4.2|2259121|54|NC_018828|CRT matches to NC_018828 position: 1751088-1751141, mismatch: 2

actggcagcggccctggcagcggccctggcagcggccctggcagcggcactggc	CRISPR spacer
actggcagcggccctggcagcggccctggcagcggcactggcagcggccctggc	Protospacer
************************************ *********** *****

19. spacer 4.3|2259193|66|NC_018828|CRT matches to NC_018828 position: 1751376-1751441, mismatch: 8

actggcagcggccctggcagcgtcccaggcagcgtcccaggcagcggccctggcagcggc	CRISPR spacer
actggcagcggccctggcagcgtcccaggcagcgtcccaggcagcggcactggcatcggc	Protospacer
************************************************ ****** ****

20. spacer 4.4|2259277|42|NC_018828|CRT matches to NC_018828 position: 1751256-1751297, mismatch: 0

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggcactggcagcggccctggcagcggcactggc	Protospacer
******************************************

21. spacer 4.4|2259277|42|NC_018828|CRT matches to NC_018828 position: 1751076-1751117, mismatch: 1

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggcactggcagcggccctggcagcggccctggc	Protospacer
************************************ *****

22. spacer 4.4|2259277|42|NC_018828|CRT matches to NC_018828 position: 1751112-1751153, mismatch: 1

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggcactggcagcggccctggcatcggcactggc	Protospacer
******************************* **********

23. spacer 4.4|2259277|42|NC_018828|CRT matches to NC_018828 position: 1751208-1751249, mismatch: 1

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggcactggcagcggccctggcagcggccctggc	Protospacer
************************************ *****

24. spacer 4.4|2259277|42|NC_018828|CRT matches to NC_018828 position: 1751232-1751273, mismatch: 1

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggccctggcagcggccctggcagcggcactggc	Protospacer
************ *****************************

25. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751184-1751213, mismatch: 2

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcggccctggc	Protospacer
********************** *** ***

26. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751364-1751381, mismatch: 0

ccaggcagcggcactggc	CRISPR spacer
ccaggcagcggcactggc	Protospacer
******************

27. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751412-1751429, mismatch: 0

ccaggcagcggcactggc	CRISPR spacer
ccaggcagcggcactggc	Protospacer
******************

28. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751064-1751081, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
ccaggcagcggccctggc	Protospacer
************ *****

29. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751076-1751093, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

30. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751112-1751129, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

31. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751196-1751213, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
ccaggcagcggccctggc	Protospacer
************ *****

32. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751208-1751225, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

33. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751256-1751273, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

34. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751280-1751297, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

35. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751448-1751465, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

36. spacer 4.7|2259421|42|NC_018828|CRT matches to NC_018828 position: 1751400-1751441, mismatch: 0

ccaggcagcgtcccaggcagcggcactggcatcggcactggc	CRISPR spacer
ccaggcagcgtcccaggcagcggcactggcatcggcactggc	Protospacer
******************************************

37. spacer 4.7|2259421|42|NC_018828|CRT matches to NC_018828 position: 1751184-1751225, mismatch: 2

ccaggcagcgtcccaggcagcggcactggcatcggcactggc	CRISPR spacer
ccaggcagcgtcccaggcagcggccctggcagcggcactggc	Protospacer
************************ ****** **********

38. spacer 4.7|2259421|42|NC_018828|CRT matches to NC_018828 position: 1751352-1751393, mismatch: 2

ccaggcagcgtcccaggcagcggcactggcatcggcactggc	CRISPR spacer
ccaggcagcgtcccaggcagcggcactggcagcggccctggc	Protospacer
******************************* **** *****

Protein sequences of NC_018828.1|WP_015039444.1|1757655_1758030_+|hypothetical-protein

>NC_018828.1|WP_015039444.1|1757655_1758030_+|hypothetical-protein
MQREQGVGLDFLRIRPSEPMLFIDKAEIARCVTYRQAVRLAWDMRQPRGMTMRTLAELCGMYPQHVSSYLHEDPLLPSSFAKPSPSAFSIELMGWSLRTLSDIRDSLVGWALSFAQRCGRDVRS

Self-targetings in the prophage

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751160-1751189	0
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751160-1751189	1
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751388-1751417	0
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751388-1751417	1
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751172-1751201	1
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751172-1751201	0
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751304-1751333	1
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751304-1751333	2
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751316-1751345	1
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751316-1751345	0
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751040-1751069	2
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751052-1751081	2
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751328-1751357	2
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751328-1751357	1
NC_018828_4	Orphan	4.1|2259073|30|NC_018828|CRT	2259073-2259102	30	1751340-1751369	2
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751340-1751369	1
NC_018828_4	Orphan	4.2|2259121|54|NC_018828|CRT	2259121-2259174	54	1751220-1751273	0
NC_018828_4	Orphan	4.2|2259121|54|NC_018828|CRT	2259121-2259174	54	1751088-1751141	2
NC_018828_4	Orphan	4.3|2259193|66|NC_018828|CRT	2259193-2259258	66	1751376-1751441	8
NC_018828_4	Orphan	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	1751256-1751297	0
NC_018828_4	Orphan	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	1751076-1751117	1
NC_018828_4	Orphan	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	1751112-1751153	1
NC_018828_4	Orphan	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	1751208-1751249	1
NC_018828_4	Orphan	4.4|2259277|42|NC_018828|CRT	2259277-2259318	42	1751232-1751273	1
NC_018828_4	Orphan	4.5|2259337|30|NC_018828|CRT	2259337-2259366	30	1751184-1751213	2
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751364-1751381	0
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751412-1751429	0
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751064-1751081	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751076-1751093	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751112-1751129	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751196-1751213	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751208-1751225	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751256-1751273	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751280-1751297	1
NC_018828_4	Orphan	4.6|2259385|18|NC_018828|CRT	2259385-2259402	18	1751448-1751465	1
NC_018828_4	Orphan	4.7|2259421|42|NC_018828|CRT	2259421-2259462	42	1751400-1751441	0
NC_018828_4	Orphan	4.7|2259421|42|NC_018828|CRT	2259421-2259462	42	1751184-1751225	2
NC_018828_4	Orphan	4.7|2259421|42|NC_018828|CRT	2259421-2259462	42	1751352-1751393	2

1. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751160-1751189, mismatch: 0

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

2. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751160-1751189, mismatch: 1

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

3. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751388-1751417, mismatch: 0

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

4. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751388-1751417, mismatch: 1

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

5. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751172-1751201, mismatch: 1

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

6. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751172-1751201, mismatch: 0

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

7. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751304-1751333, mismatch: 1

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtaccaggcagcgtcccaggc	Protospacer
*********** ******************

8. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751304-1751333, mismatch: 2

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtaccaggcagcgtcccaggc	Protospacer
** ******** ******************

9. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751316-1751345, mismatch: 1

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
** ***************************

10. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751316-1751345, mismatch: 0

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcgtcccaggc	Protospacer
******************************

11. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751040-1751069, mismatch: 2

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcggccctggcagcgtcccaggc	Protospacer
********** *** ***************

12. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751052-1751081, mismatch: 2

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
cctggcagcgtcccaggcagcggccctggc	Protospacer
********************** *** ***

13. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751328-1751357, mismatch: 2

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcggcccaggc	Protospacer
** ******************* *******

14. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751328-1751357, mismatch: 1

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcggcccaggc	Protospacer
********************** *******

15. spacer 4.1|2259073|30|NC_018828|CRT matches to NC_018828 position: 1751340-1751369, mismatch: 2

cctggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcggcccaggcagcgtcccaggc	Protospacer
** ******* *******************

16. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751340-1751369, mismatch: 1

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcggcccaggcagcgtcccaggc	Protospacer
********** *******************

17. spacer 4.2|2259121|54|NC_018828|CRT matches to NC_018828 position: 1751220-1751273, mismatch: 0

actggcagcggccctggcagcggccctggcagcggccctggcagcggcactggc	CRISPR spacer
actggcagcggccctggcagcggccctggcagcggccctggcagcggcactggc	Protospacer
******************************************************

18. spacer 4.2|2259121|54|NC_018828|CRT matches to NC_018828 position: 1751088-1751141, mismatch: 2

actggcagcggccctggcagcggccctggcagcggccctggcagcggcactggc	CRISPR spacer
actggcagcggccctggcagcggccctggcagcggcactggcagcggccctggc	Protospacer
************************************ *********** *****

19. spacer 4.3|2259193|66|NC_018828|CRT matches to NC_018828 position: 1751376-1751441, mismatch: 8

actggcagcggccctggcagcgtcccaggcagcgtcccaggcagcggccctggcagcggc	CRISPR spacer
actggcagcggccctggcagcgtcccaggcagcgtcccaggcagcggcactggcatcggc	Protospacer
************************************************ ****** ****

20. spacer 4.4|2259277|42|NC_018828|CRT matches to NC_018828 position: 1751256-1751297, mismatch: 0

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggcactggcagcggccctggcagcggcactggc	Protospacer
******************************************

21. spacer 4.4|2259277|42|NC_018828|CRT matches to NC_018828 position: 1751076-1751117, mismatch: 1

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggcactggcagcggccctggcagcggccctggc	Protospacer
************************************ *****

22. spacer 4.4|2259277|42|NC_018828|CRT matches to NC_018828 position: 1751112-1751153, mismatch: 1

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggcactggcagcggccctggcatcggcactggc	Protospacer
******************************* **********

23. spacer 4.4|2259277|42|NC_018828|CRT matches to NC_018828 position: 1751208-1751249, mismatch: 1

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggcactggcagcggccctggcagcggccctggc	Protospacer
************************************ *****

24. spacer 4.4|2259277|42|NC_018828|CRT matches to NC_018828 position: 1751232-1751273, mismatch: 1

cctggcagcggcactggcagcggccctggcagcggcactggc	CRISPR spacer
cctggcagcggccctggcagcggccctggcagcggcactggc	Protospacer
************ *****************************

25. spacer 4.5|2259337|30|NC_018828|CRT matches to NC_018828 position: 1751184-1751213, mismatch: 2

ccaggcagcgtcccaggcagcgtcccaggc	CRISPR spacer
ccaggcagcgtcccaggcagcggccctggc	Protospacer
********************** *** ***

26. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751364-1751381, mismatch: 0

ccaggcagcggcactggc	CRISPR spacer
ccaggcagcggcactggc	Protospacer
******************

27. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751412-1751429, mismatch: 0

ccaggcagcggcactggc	CRISPR spacer
ccaggcagcggcactggc	Protospacer
******************

28. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751064-1751081, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
ccaggcagcggccctggc	Protospacer
************ *****

29. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751076-1751093, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

30. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751112-1751129, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

31. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751196-1751213, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
ccaggcagcggccctggc	Protospacer
************ *****

32. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751208-1751225, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

33. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751256-1751273, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

34. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751280-1751297, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

35. spacer 4.6|2259385|18|NC_018828|CRT matches to NC_018828 position: 1751448-1751465, mismatch: 1

ccaggcagcggcactggc	CRISPR spacer
cctggcagcggcactggc	Protospacer
** ***************

36. spacer 4.7|2259421|42|NC_018828|CRT matches to NC_018828 position: 1751400-1751441, mismatch: 0

ccaggcagcgtcccaggcagcggcactggcatcggcactggc	CRISPR spacer
ccaggcagcgtcccaggcagcggcactggcatcggcactggc	Protospacer
******************************************

37. spacer 4.7|2259421|42|NC_018828|CRT matches to NC_018828 position: 1751184-1751225, mismatch: 2

ccaggcagcgtcccaggcagcggcactggcatcggcactggc	CRISPR spacer
ccaggcagcgtcccaggcagcggccctggcagcggcactggc	Protospacer
************************ ****** **********

38. spacer 4.7|2259421|42|NC_018828|CRT matches to NC_018828 position: 1751352-1751393, mismatch: 2

ccaggcagcgtcccaggcagcggcactggcatcggcactggc	CRISPR spacer
ccaggcagcgtcccaggcagcggcactggcagcggccctggc	Protospacer
******************************* **** *****