CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_019941	Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence	2 crisprs	DEDDh,RT	0	6	1	0
NC_019940	Thioflavicoccus mobilis 8321, complete sequence	6 crisprs	cas6,PD-DExK,cmr6gr7,cmr5gr11,cmr4gr7,cmr3gr5,cas10,csx1,cas2,cas1,RT,cas3,cas8u1,csb2gr5,csb1gr7,WYL,DEDDh,csa3,DinG	0	12	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_019941_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019941_1

44518-44689

Orphan

Consensus_repeat	Method
GTTCTGCTACAGATTTATGGT	PILER-CR

3 spacers

The CRISPR arrays of NC_019941_1

>merge|NC_019941|1|44518-44689|PILER-CR
TGCTACAGATTTATGGTCCGGGGCTCTGGGGCCGACCTGAGGCTCCGATCTGCTACAGATTTATGGTTCCGGCCCAGGTCGGCCTGTTCTGCTACAGAAATATGGTCCTCCCGGTTCTGCTACAGATTTATGGTGCACGGCTCAAGGCGTCGTTCTGCTACAGATTTATGGT

>NC_019941|1|1|44518-44689|PILER-CR
TGCTACAGATTTATGGTCCGG	GGCTCTGGGGCCGACCTGAGGCTCCGATC
TGCTACAGATTTATGGTTCCG	GCCCAGGTCGGCCTGTTCTGCTACAGAAATATGGTCCTCCCGGTTC
TGCTACAGATTTATGGTGCAC	GGCTCAAGGCGTCGTTC
TGCTACAGATTTATGGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019941.1\|WP_015282516.1\|41837_42149_-\|hypothetical-protein	unknown	unknown	unknown
NC_019941.1\|WP_015282524.1\|48026_50375_+\|VirB4-family-type-IV-secretion/conjugal-transfer-ATPase	unknown	unknown	gnl\|CDD\|273346
NC_019941.1\|WP_015282521.1\|46671_47307_+\|lytic-transglycosylase-domain-containing-protein	unknown	unknown	gnl\|CDD\|381613
NC_019941.1\|WP_015282515.1\|40439_41600_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|224292
NC_019941.1\|WP_015282517.1\|42205_43876_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376240
NC_019941.1\|WP_015282512.1\|38543_38939_-\|hypothetical-protein	unknown	unknown	unknown
NC_019941.1\|WP_041604717.1\|45502_46522_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378890
NC_019941.1\|WP_172637486.1\|34956_36072_-\|hypothetical-protein	unknown	unknown	unknown
NC_019941.1\|WP_015282519.1\|44782_45502_+\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
NC_019941.1\|WP_015282510.1\|37339_38098_-\|ParA-family-protein	unknown	unknown	gnl\|CDD\|224113
NC_019941.1\|WP_015282527.1\|51594_52707_+\|type-IV-secretion-system-protein	unknown	unknown	gnl\|CDD\|377390
NC_019941.1\|WP_015282528.1\|52708_52900_+\|hypothetical-protein	unknown	unknown	unknown
NC_019941.1\|WP_015282522.1\|47406_47754_+\|TrbC/VirB2-family-protein	unknown	unknown	gnl\|CDD\|368210
NC_019941.1\|WP_015282514.1\|39314_39833_-\|DNA-repair-protein-RadC	unknown	unknown	gnl\|CDD\|178801
NC_019941.1\|WP_015282513.1\|39027_39192_-\|hypothetical-protein	unknown	unknown	unknown
NC_019941.1\|WP_015282511.1\|38198_38441_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372250
NC_019941.1\|WP_015282509.1\|36299_37343_-\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|272946
NC_019941.1\|WP_015282523.1\|47757_48030_+\|VirB3-family-type-IV-secretion-system-protein	unknown	unknown	gnl\|CDD\|368285
NC_019941.1\|WP_015282525.1\|50371_51100_+\|type-IV-secretion-system-protein	unknown	unknown	gnl\|CDD\|369643
NC_019941.1\|WP_015282526.1\|51150_51588_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_019941.1\|WP_015282511.1\|38198_38441_-\|hypothetical-protein	gnl\|CDD\|372250	pfam12668, DUF3791, Protein of unknown function (DUF3791). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 71 and 125 amino acids in length.	0.00162847
NC_019941.1\|WP_015282524.1\|48026_50375_+\|VirB4-family-type-IV-secretion/conjugal-transfer-ATPase	gnl\|CDD\|273346	TIGR00929, CAG_pathogenicity_island_protein_23, type IV secretion/conjugal transfer ATPase, VirB4 family. Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).	0
NC_019941.1\|WP_015282521.1\|46671_47307_+\|lytic-transglycosylase-domain-containing-protein	gnl\|CDD\|381613	cd16892, LT_VirB1-like, VirB1-like subfamily. This subfamily includes VirB1 protein, one of twelve proteins making up type IV secretion systems (T4SS). T4SS are macromolecular assemblies generally composed of VirB1-11 and VirD4 proteins, and are used by bacteria to transport material across their membranes. VirB1 acts as a lytic transglycosylase (LT), and is important with respect to piercing the peptidoglycan layer in the periplasm. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc) as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL).	4.46993e-69
NC_019941.1\|WP_015282515.1\|40439_41600_+\|ATP-binding-protein	gnl\|CDD\|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	6.04725e-58
NC_019941.1\|WP_015282517.1\|42205_43876_-\|hypothetical-protein	gnl\|CDD\|376240	pfam18821, LPD7, Large polyvalent protein-associated domain 7. This domain contains conserved aspartate and phenylalanine residues. It is widely present in polyvalent proteins and gene neighbourhoods of conjugative elements. This domain is also known as PTox1.	3.94818e-10
NC_019941.1\|WP_041604717.1\|45502_46522_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|378890	pfam12625, Arabinose_bd, Arabinose-binding domain of AraC transcription regulator, N-term. AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].	3.91002e-30
NC_019941.1\|WP_015282523.1\|47757_48030_+\|VirB3-family-type-IV-secretion-system-protein	gnl\|CDD\|368285	pfam05101, VirB3, Type IV secretory pathway, VirB3-like protein. This family includes the Type IV secretory pathway VirB3 protein, that is found associated with bacterial inner and outer membranes. The family also includes the conjugal transfer protein TrbD family that contains a nucleotide binding motif and may provide energy for the export of DNA or the export of other Trb proteins.	3.39638e-25
NC_019941.1\|WP_015282519.1\|44782_45502_+\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	3.23041e-59
NC_019941.1\|WP_015282510.1\|37339_38098_-\|ParA-family-protein	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	9.89334e-51
NC_019941.1\|WP_015282527.1\|51594_52707_+\|type-IV-secretion-system-protein	gnl\|CDD\|377390	pfam04610, TrbL, TrbL/VirB6 plasmid conjugal transfer protein.	4.17953e-24
NC_019941.1\|WP_015282522.1\|47406_47754_+\|TrbC/VirB2-family-protein	gnl\|CDD\|368210	pfam04956, TrbC, TrbC/VIRB2 family. Conjugal transfer protein, TrbC has been identified as a subunit of the pilus precursor in bacteria. The protein undergoes three processing steps before gaining its mature cyclic structure. This family also contains several VIRB2 type IV secretion proteins. The virB2 gene encodes a putative type IV secretion system and is known to be a pathogenicity factor in Bartonella species.	1.53057e-06
NC_019941.1\|WP_015282514.1\|39314_39833_-\|DNA-repair-protein-RadC	gnl\|CDD\|178801	PRK00024, PRK00024, DNA repair protein RadC.	3.11232e-62
NC_019941.1\|WP_015282509.1\|36299_37343_-\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|272946	TIGR00180, Probable_chromosome-partitioning_protein_ParB, ParB/RepB/Spo0J family partition protein. This model represents the most well-conserved core of a set of chromosomal and plasmid partition proteins related to ParB, including Spo0J, RepB, and SopB. Spo0J has been shown to bind a specific DNA sequence that, when introduced into a plasmid, can serve as partition site. Study of RepB, which has nicking-closing activity, suggests that it forms a transient protein-DNA covalent intermediate during the strand transfer reaction.	8.93208e-39
NC_019941.1\|WP_015282525.1\|50371_51100_+\|type-IV-secretion-system-protein	gnl\|CDD\|369643	pfam07996, T4SS, Type IV secretion system proteins. Members of this family are components of the type IV secretion system. They mediate intracellular transfer of macromolecules via a mechanism ancestrally related to that of bacterial conjugation machineries.	2.428e-42

>NC_019941.1|WP_015282517.1|42205_43876_-|hypothetical-protein
MADTQSIVLGSDSGTFWQEGDTWTDDPSEAKSFDNPRQAWHQAVRLQSTQADYLEDSPVELHLRDSDEPRLTRRVTSLAAQNNRPALRRQWRTNFGEPLPPDLPSPLQSDEVYRLEDFLSDVDWDALRSRYGSPDKMYAALDSSFRAALKQAAESDREPVSRMLHQLVPRDVSSAMQSDWRRAPFTKQVPVPENSREASGVEHNEISRDRLREHTPVDAPSPPPIPASRTGAAADSRTKSPADQLPDFVRRHFVRSGAEFFYRQTPDKLAFETRGETFHAHDSSVSVATAMVEMAEARGWSALKVKGSKDFRRLVWAAAAKRGLSVNGYAPSAGERAMLEQDQEASRPPQRDALGSRADGRQRERPADPLAGTFVDYGSAPFRNQQGNSPSYFVSLRSESGSVTTHWGLDLERAMDESGADVGDQVRLARLGKQRVQVQEPVRDQRGNVVDHVTRETERNSWSVTVLSRSDRSDDAQRGQRPEADADPIAAKVVELFTAERLGILPPEEQARFRELYAQARSRLDSREISTHDLADQPGRNLVSRDRHRERAAQGR
>NC_019941.1|WP_015282516.1|41837_42149_-|hypothetical-protein
MNPYLHPVWSEWIRGAHHGGAQALQNLALHLYNSREWPVNLGYICSMSDDHWEAALAMILDYRENGENNREFMAMCEAIAEERSERTAVEARDDDSGQDMAGS
>NC_019941.1|WP_015282515.1|40439_41600_+|ATP-binding-protein
MIPRTIGAKVEAALARQAAVGLIGPRQVGKTTLAHEIAKTQPSIYLDLEAAADRDKLSDPVLFLDRHVDKLVILDEIHRVPALFEALRGIIDAGRRAGHRTGRFLILGSATIDLLRQSGESLAGRITYVDLAPLTADEVDRSDLEQLWLRGGFPDSFLAATDEDSLELRESFVRTYLERDVPMFGPRIPAETLRRLWTMLAHNQGTLLNASRLASGLSVSAPTVTSYIDLLVDLLLVRRLPPFHANVGKRLVKSPKTYVRDSGLTHALLNIETFEDLLGHPVSGPSWEGFVIENLITAAPSRTQASFYRTAAGAEIDLLLELGDKRGTWAVEIKRSLAAKPQRGFYNAVEDIQPTKAFVVHAGDDRYPISESVEAVGLREMIGLLS
>NC_019941.1|WP_015282514.1|39314_39833_-|DNA-repair-protein-RadC
MTQQILSFPANASTNRFADLRPGDLSADEKASLVELALTILARKHRRGSALTSPEATRSYLRLEIGERHHELFGCLFLDNRHRIIAKEELFYGTIDGASVHPRVVVARALELNAAAVVFFHNHPSGVAEPSQSDLRITTRLKDALALVDVRVLDHLVVSVEDSVSLAERGLI
>NC_019941.1|WP_015282513.1|39027_39192_-|hypothetical-protein
MEQYTDLDGNLITVPELTWLEDGRDNDGNHCARYAIGNEESVWLDWHGQEVERE
>NC_019941.1|WP_015282512.1|38543_38939_-|hypothetical-protein
MFEDADLIHRYTRADALEDGTLVDVTETAKGVGFRIPVALTRTAWSDCVAWTEEDNERVVYQDESGRLWDLLWMAINAARRNTEASRLEFKVLRVPRDSRTGQPVSVTLVLDIGPGDQGEAVITIGFAEDF
>NC_019941.1|WP_015282511.1|38198_38441_-|hypothetical-protein
MPEKVPMARMQLLLPPDLKAEIEQFAEEQGLSANEAIRLLSRRGLSASGKPAPVEALLEELGYRVRDLEQRVEKAEGSSA
>NC_019941.1|WP_015282510.1|37339_38098_-|ParA-family-protein
MQIIAIANQKGGVGKSTLAVHLAWLALEQERPVLLVDMDGQANSSRTFTDEFTGVLASKLFTEAPGTLKGSPQAISDQFSLIPADMAINDVEGLELETIERPAAHIRALPLTAETLVIIDTPPTLGRRLLSALIAADAVVSPVALNGYSIQGITDLQKTIQTVMRRFNPRLKNLGLLANMVNSRSATHAQMLGELRQVLGDKLLSVTLGHRVAISDAIDRGRPVWQGTRGESAQRAAQEMRGVCTAILEKLS
>NC_019941.1|WP_015282509.1|36299_37343_-|ParB/RepB/Spo0J-family-partition-protein
MSLKGISSLAELMDTPAEAGAQEIALSLIDPDPNQPRTSFDELRLENLAASVKAQGVIEPLIVSHHPETAGRYMLIAGERRWRAAGKAGLTLVPVVIRELTGDQRLAVQLVENIDREELSVMEEALAVTRLLDFGRKPKEVADMLGKTAAWVSLRKKIAKHQAILEYFVVQGQTGDAETLAMLVDLEKIDRKAFEDMLQQDQVGRAMVREALDLAKARKEEAVNPKKSPIPKVTDPSESAHGGEEAAAERTGTSARSRSEGEASDPESPAAGTEEETPARSKASRTKRKGDSGSEGGSAAYDEIARALQTTLGLPVTIDAPRDGKSGELRIGFANLLELEGLQQNLT
>NC_019941.1|WP_172637486.1|34956_36072_-|hypothetical-protein
MHLESSAYGRAWECDRRVGVGGGCEGAIQLREDDELTELQIAEAIARRTLGGDSSAHRQGQPEYHHVIGPLEEIARSGYLSGPQRRVLEEARVIVKRLASAAALAKDQARRQEKAREAAVEGRCRQAMGLLGPSLAPDTTRLEASVVDLLALARFGGDACSTGPDILANDSIEALENLLSSRAAGEQRTAADVIFADLLSAHQGLREGISRDWSARSEPIEDLHARFIATLPRLREAILSSPPPYLQVVRRLLAEIAPDNVVPLAPRLSSMTPIPNQTRRRVISAFRFHSQRSPAESAALLTSFAVKRGLSDPRRPPPGSALEQWATAAKAPLWAVQAAASWLDAHATVTDPEEQAAVAAVLEQTGGGGEG
>NC_019941.1|WP_015282519.1|44782_45502_+|replication-initiation-protein
MDQQRSITVRADGNSIVTKANALIEASYNLTLNEQRIILACAAKLDSRKPMPREAVFVLDADEFVELFGSDPRNAYAEMEEAASKLYERDIRRIEGKTRKRLRWVYMAEYQKGAGRVKLGFSPEIAPYLTMLHKRFTSYRLEEVASLRSTYAIRLFEMLAQYSDTGVFLITVADFKQRLGIEDKYDRFSNLKARVIQPAIKDLQTKTSLDITWQGVKKGKSVERLEFRFEEKRQMQLDI
>NC_019941.1|WP_041604717.1|45502_46522_+|AraC-family-transcriptional-regulator
MGRAREAMSSTILATAGRIVHRLIERVGLEADAMFLSAGLDPQKLNDPQARYPLERSRQLLHQVNEQIQDPCWGLAAGELWRPTDFHALGYAYLASGTLESALKRMERYFRIVIQGWSVQSSIRDDDFCMTHLIPTDMADLPANHDARLSISLRMCREIYGQEFRFREVRLAHPWQACGYEDFFGCPVRYDADYTGFTIPIDVVRRPLPAKNRDLARANDRILQDLDRRLLDGSMLGRVKNAILDSLPDGKPSAQGIARKLAVSPRTLQRKLQEEGTTFQAVLDGVRKELAEDYLRSGEYDLQTITYLTGFANPPAFSRAFKKWTGRSPSEERESQNYS
>NC_019941.1|WP_015282521.1|46671_47307_+|lytic-transglycosylase-domain-containing-protein
MDLITLIATCAPMVAPITMKAIVLEESRGHPYAIHDSKRRRALFPKTREQAIATARELLAAGHRIDAGLAQINSENWEWLGLSPETVFDPCINLAAGERVLVDAYARAPFTVDAAISRYNSGDAERGIRNGYVSRVKAWMPKPPPDRRYEVEDVPLNDYVPTDPVVVGVSLAQDLAADAGPTDQPALAQDPPESNAKPWRFEAVLDGFDGG
>NC_019941.1|WP_015282522.1|47406_47754_+|TrbC/VirB2-family-protein
MTQANATDPTTRGIAAVTLLAALALAPEIASANVLDNFGNAILGILNNTFLRAVAIAAVIGAGLMALSGRIQWMAFISVMIAVVIIFGSAGIVDYIRDNSATAALDPAPIVERVA
>NC_019941.1|WP_015282523.1|47757_48030_+|VirB3-family-type-IV-secretion-system-protein
MSDPLFQGMTRPAMLAGVTYSGVILNMMLVITPFVMLNSLWSLLAAIPIHGAMWLVCKWDPRFFDLVMVWMQTSANARHRYIWKGSTYRP
>NC_019941.1|WP_015282524.1|48026_50375_+|VirB4-family-type-IV-secretion/conjugal-transfer-ATPase
MNALIKIHSEERTAATLVPIQSHLTAGIAKTRDGALVAAFELGGTAFEAKTPEQRDRYKEQLNVALRNSASPRLALWSALTRRRVHPDLAREYPNAFAQGVADAYTGLQEARTLYQNRLWLTLVYRVTGLRTEIAFSKKADKRLVRNLLTAGIDELEEITAKLGQALVDYSPRRLGVYEHADNRFSEIAELYGLLLNHNAERVPLGPYDLSQAVGRNRLLFGREIFEIRRPGNSRFGAALAIKEYVPRTYPEMFTGLMEEPYELNWVQSFAFLEKDKAKDLFATQRRRLVSAGDAAISQVEALEDAMDQLISNRFVLGEHNAALIIYGDDLEALARNVAFGHATLSDPGNVIVREDMALEGQVYATLPGNTKYRPRKAPVTSLNFAAMSPFYAFPTGSPNGHHWGEAVSLFRSTVDTPLWFSPHVGDLGHTSVIGMSGAGKTALLAFLLCQFQRFPVRHVILDKDQGLKLAVLALDGEYLSLKTGEPTGFNPFALPLTASHSNYLHDLVRLLVGGGEGNWDANASREVEEGIRAVYSLRPENRRLGSLAQFLDGTQLGGVAERLRPWVGEGRFAWAFDNREDTLELGRLTGFDVTEFLDHPDLRTPITSYLLYRTEPLIDGTPFALWIDEFWRLLDDPYFEGFVRDKLKTIRKKDGIVITSTQSPADALGSRIASALLEQTPTKIFLPNEYADEKDYRDGFKLTPAEWDLLRPLTKSSRKFLLKQAAGSSLVDFNLAGMDREMAILSGTERLIRIADGLAEANGGDLPEDWLSLLEQKRRSP
>NC_019941.1|WP_015282525.1|50371_51100_+|type-IV-secretion-system-protein
MKKHLLVAVVGAALAGPLSGPAHAAGVPVIDASNLAQAVAQVQALADQLTTLQDQLNTLRDQYTTITNMYNEMRGITGHALMLPNPVDALHDFLPAANLDPDDLLSGPLAALANSLRDANELYSAAELFGGTHLTGAARQYQERSDFIFSYMALAKEAYENIAARRATLEGFATAAGTATTEKAILDLNARIAAENALLLNDLAQLQALQIMAQMQEQNLVHNSQGLHANRPTGVGDLDFGE
>NC_019941.1|WP_015282526.1|51150_51588_+|hypothetical-protein
MKRATALLALGLPVVANAWTVEGVDMDAVPWAELCPSIEAVELTTGAGSCATVHPASHRHAKWDGFDMGVKEPSLNCRKLEREYQRFTSPRPGTTEATKPRDRWGTCIGAFSRALKLRAEEPGRFSEPLDTWRQRYFEGYIHREG
>NC_019941.1|WP_015282527.1|51594_52707_+|type-IV-secretion-system-protein
MDVFTSLFEALDEVLGDYVNEAITAATGYVSGPIAVLGTISFIAMGAVLLRGMSEIPLAKFVQTAALLALVFALAGTAGHYNTYLADHLRSFPDELLATFAGTALGNDAAIGAVLDRIGDQAMTGISAIWSAGGFTDPGPSLFAAVLFVIFLIFGVAAVVALATAKIGLSLVVAVGPLMILGLLFQSTREYFTKWLSYGIQFAFLAMFVGGIAGMADAIVDTYIDALDDSAENVDLVALMAPALMLLLLAKIFAELPHMASSLSGGIGLAVGNTAWRGIQGAMHQAGGKHIDAWRDAARWRRVGRAEALHNRMVETRKAVVDRLVNGAPRVSRADANRPASLSGASAANRDLDREARDHVEARRRRRAGG
>NC_019941.1|WP_015282528.1|52708_52900_+|hypothetical-protein
MQYPRPLLTALLALLLPALLGACSTVPKAPKCDQSAYRSLNPAHYDPVKESTRADVPFLLPEA

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Crispr_ID: NC_019941_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019941_2

60540-60944

Orphan

Consensus_repeat	Method
TTCCCGCCCTGATNACGGCCCTTCGCGACGAAGAAG	CRT

4 spacers

DEDDh,RT

The CRISPR arrays of NC_019941_2

>merge|NC_019941|2|60540-60944|CRT
TTCCCGCCCTGATTACGGCCCTTCGCGACGAAGAAGAGACCGTGCGTGCGTCCGCCGCGGATGCGCTTGGAGAGATTGGCCTCCCTGCCGTTCCCGCCCTGATTACGGCCCTTCGCGACGAAGAATGGGAGGTGCGCGAGCGCGCCGCCGAAGCGCTTGAAAAGATCGGGCCCGCTGCCAGCCAGGCCATTCCCGCCCTGATCACGGCCCTTCGCGATGAAGAAGATACCGTGCGTGCGTCCGCCGCGGATGCGCTTGGAGAGATTGGCCTCCCTGCCGTTCCCGCCCTGATTACGGCCCTTCGCGACGAAGAAGGGGAGGTGCGCGCGTTCGCCACCCGCGCGCTTGGAGAGATTGGCACCCCTGCTGTTCCCGACCTAATCACTGCCTACCACGACGAAGAGG

>NC_019941|2|1|60540-60944|CRT
TTCCCGCCCTGATTACGGCCCTTCGCGACGAAGAAG	AGACCGTGCGTGCGTCCGCCGCGGATGCGCTTGGAGAGATTGGCCTCCCTGCCG
TTCCCGCCCTGATTACGGCCCTTCGCGACGAAGAAT	GGGAGGTGCGCGAGCGCGCCGCCGAAGCGCTTGAAAAGATCGGGCCCGCTGCCAGCCAGGCCA
TTCCCGCCCTGATCACGGCCCTTCGCGATGAAGAAG	ATACCGTGCGTGCGTCCGCCGCGGATGCGCTTGGAGAGATTGGCCTCCCTGCCG
TTCCCGCCCTGATTACGGCCCTTCGCGACGAAGAAG	GGGAGGTGCGCGCGTTCGCCACCCGCGCGCTTGGAGAGATTGGCACCCCTGCTG
TTCCCGACCTAATCACTGCCTACCACGACGAAGAGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019941.1\|WP_015282530.1\|53578_54391_+\|TrbG/VirB9-family-P-type-conjugative-transfer-protein	unknown	unknown	gnl\|CDD\|377058
NC_019941.1\|WP_015282528.1\|52708_52900_+\|hypothetical-protein	unknown	unknown	unknown
NC_019941.1\|WP_157633897.1\|63208_63859_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|349760
NC_019941.1\|WP_015282526.1\|51150_51588_+\|hypothetical-protein	unknown	unknown	unknown
NC_019941.1\|WP_015279037.1\|67016_67379_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NC_019941.1\|WP_015279038.1\|67378_67681_-\|IS66-family-insertion-sequence-hypothetical-protein	unknown	unknown	unknown
NC_019941.1\|WP_015282543.1\|69179_70223_-\|hypothetical-protein	unknown	unknown	unknown
NC_019941.1\|WP_015282542.1\|67695_68994_+\|Retron-type-reverse-transcriptase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_019941.1\|WP_015282527.1\|51594_52707_+\|type-IV-secretion-system-protein	unknown	unknown	gnl\|CDD\|377390
NC_019941.1\|WP_015282529.1\|52934_53582_+\|type-IV-secretory-pathway,-component-VirB8	unknown	unknown	gnl\|CDD\|226259
NC_019941.1\|WP_015282535.1\|59193_59484_+\|hypothetical-protein	unknown	unknown	unknown
NC_019941.1\|WP_015282533.1\|56616_58536_+\|type-IV-secretory-system-conjugative-DNA-transfer-family-protein	unknown	unknown	gnl\|CDD\|367119
NC_019941.1\|WP_015282531.1\|54387_55557_+\|type-IV-secretion-system-protein-VirB10	unknown	unknown	gnl\|CDD\|319755
NC_019941.1\|WP_015282532.1\|55546_56623_+\|P-type-DNA-transfer-ATPase-VirB11	unknown	unknown	gnl\|CDD\|274301
NC_019941.1\|WP_015282539.1\|63910_64438_-\|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|176648
NC_019941.1\|WP_015282544.1\|70219_70564_-\|hypothetical-protein	unknown	unknown	unknown
NC_019941.1\|WP_015282540.1\|64569_64812_+\|WGR-domain-containing-protein	unknown	unknown	gnl\|CDD\|153425
NC_019941.1\|WP_015282534.1\|58562_59183_+\|TrbM	unknown	unknown	gnl\|CDD\|237548
NC_019941.1\|WP_015282537.1\|62173_63169_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271196
NC_019941.1\|WP_015279036.1\|65417_67007_-\|IS66-family-transposase	unknown	unknown	gnl\|CDD\|376980

Protein	Function_ID	Function_description	E-value
NC_019941.1\|WP_157633897.1\|63208_63859_-\|AAA-family-ATPase	gnl\|CDD\|349760	cd02042, ParAB_family, partition proteins ParAB family. ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single-stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis. ParA shares sequence similarity to a conserved and widespread family of ATPases which includes the repA protein of the repABC operon in Rhizobium etli symbiotic plasmid. This operon is involved in the plasmid replication and partition.	3.00239e-27
NC_019941.1\|WP_015282542.1\|67695_68994_+\|Retron-type-reverse-transcriptase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	3.85693e-65
NC_019941.1\|WP_015282529.1\|52934_53582_+\|type-IV-secretory-pathway,-component-VirB8	gnl\|CDD\|226259	COG3736, VirB8, Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion].	7.67203e-50
NC_019941.1\|WP_015279037.1\|67016_67379_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	8.2129e-42
NC_019941.1\|WP_015282539.1\|63910_64438_-\|3'-5'-exonuclease	gnl\|CDD\|176648	cd06127, DEDDh, DEDDh 3'-5' exonuclease domain family. DEDDh exonucleases, part of the DnaQ-like (or DEDD) exonuclease superfamily, catalyze the excision of nucleoside monophosphates at the DNA or RNA termini in the 3'-5' direction. These proteins contain four invariant acidic residues in three conserved sequence motifs termed ExoI, ExoII and ExoIII. DEDDh exonucleases are classified as such because of the presence of specific Hx(4)D conserved pattern at the ExoIII motif. The four conserved acidic residues are clustered around the active site and serve as ligands for the two metal ions required for catalysis. Most DEDDh exonucleases are the proofreading subunits (epsilon) or domains of bacterial DNA polymerase III, the main replicating enzyme in bacteria, which functions as the chromosomal replicase. Other members include other DNA and RNA exonucleases such as RNase T, Oligoribonuclease, and RNA exonuclease (REX), among others.	3.2842e-33
NC_019941.1\|WP_015282527.1\|51594_52707_+\|type-IV-secretion-system-protein	gnl\|CDD\|377390	pfam04610, TrbL, TrbL/VirB6 plasmid conjugal transfer protein.	4.17953e-24
NC_019941.1\|WP_015282533.1\|56616_58536_+\|type-IV-secretory-system-conjugative-DNA-transfer-family-protein	gnl\|CDD\|367119	pfam02534, T4SS-DNA_transf, Type IV secretory system Conjugative DNA transfer. These proteins contain a P-loop and walker-B site for nucleotide binding. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. The C-terminus of this domain interacts with the relaxosome component TraM via the latter's tetramerisation domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore. The family contains a number of different DNA transfer proteins.	1.45583e-102
NC_019941.1\|WP_015282530.1\|53578_54391_+\|TrbG/VirB9-family-P-type-conjugative-transfer-protein	gnl\|CDD\|377058	pfam03524, CagX, Conjugal transfer protein. This family includes type IV secretion system CagX conjugation protein. Other members of this family are involved in conjugal transfer to plant cells of T-DNA.	1.09429e-67
NC_019941.1\|WP_015282532.1\|55546_56623_+\|P-type-DNA-transfer-ATPase-VirB11	gnl\|CDD\|274301	TIGR02788, conjugal_transfer_protein, P-type DNA transfer ATPase VirB11. The VirB11 protein is found in the vir locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for DNA transfer. VirB11 is believed to be an ATPase. VirB11 is a homolog of the P-like conjugation system TrbB protein and the Flp pilus sytem protein TadA.	8.0988e-118
NC_019941.1\|WP_015282540.1\|64569_64812_+\|WGR-domain-containing-protein	gnl\|CDD\|153425	cd07996, WGR_MMR_like, WGR domain of molybdate metabolism regulator and related proteins. The WGR domain is found in the putative Escherichia coli molybdate metabolism regulator and related bacterial proteins, as well as in various other bacterial proteins of unknown function. It has been called WGR after the most conserved central motif of the domain. The domain appears to occur in single-domain proteins and in a variety of domain architectures, together with ATP-dependent DNA ligase domains, WD40 repeats, leucine-rich repeats, and other domains. It has been proposed to function as a nucleic acid binding domain.	5.89427e-13
NC_019941.1\|WP_015282531.1\|54387_55557_+\|type-IV-secretion-system-protein-VirB10	gnl\|CDD\|319755	cd16429, VirB10, VirB10 forms part of core complex in Type IV secretion system (T4SS). This family contains VirB10, a component of the type IV secretion system (T4SS), including homologs TrbI, TraF, TrwE and TraL. T4S system is employed by pathogenic bacteria to export virulence DNAs and/or proteins directly from the bacterial cytoplasm into the host cell. It forms a large multiprotein complex consisting of 12 proteins termed VirB1-11 and VirD4. VirB10, interacts with VirB7 and VirB9, forming the membrane-spanning 'core complex' (CC), around which all other components assemble. The CC is inserted in both, the outer and inner membranes, playing a fundamental role as a scaffold for the rest of the T4SS components and actively participating in T4S substrate transfer through the bacterial envelope via conformational changes regulating channel opening and closing. TrwE in R33 plasmid has been shown to be anchored to the inner membrane and its C-terminal is necessary for conjugation; the transmembrane domains of TrwB and TrwE are involved in TrwB-TrwE interactions. TraF protein of the RP4 plasmid is involved in circularization of pilin subunits of P-type pili. In gonococcal genetic island (GGI) of Neisseria gonorrhoeae, T4SS encodes TrbI and circularization occurs via a covalent intermediate between the C terminus of putative pilin protein TraA and TrbI.	9.75818e-65
NC_019941.1\|WP_015282534.1\|58562_59183_+\|TrbM	gnl\|CDD\|237548	PRK13893, PRK13893, conjugal transfer protein TrbM; Provisional.	2.36996e-18
NC_019941.1\|WP_015282537.1\|62173_63169_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271196	cd01196, INT_C_like_6, Uncharacterized site-specific tyrosine recombinase, C-terminal catalytic domain. Tyrosine recombinase (integrase) belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	7.26761e-81
NC_019941.1\|WP_015279036.1\|65417_67007_-\|IS66-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	1.51121e-89

>NC_019941.1|WP_015282535.1|59193_59484_+|hypothetical-protein
MENDIEMAKADRSRQRALVNKEKVSAALQELADEHRGNPRSDTARLREVLDDVEEALSAGASHSAVLDTLHNQGFTLTLSSFQSTLARLRRERRTT
>NC_019941.1|WP_015282534.1|58562_59183_+|TrbM
MNRTPIVLSLSASLLGAGLGASTPAQALSGDQESACGAILCLVGGSGVAECAPYLARYFAITAPNPAKLFDRRLDFLNLCPASDLPGDVRPLIARYGATCQPATLVNWLNAQIRSCQIRDWDGSDDCRPTGDEWRMCAPFFDHGYTTYEAPTLHEQCREERDGYGYLVETCFYTWTEAGAPTPTETSPTPTGTWPFGRTSRFDLTD
>NC_019941.1|WP_015282533.1|56616_58536_+|type-IV-secretory-system-conjugative-DNA-transfer-family-protein
MLKRPTAAIKWVIALSIPLGLVSFLPVASWVYAELCDYKFMVVVWLSGLQHGLQPDNLLLAGLAGGASAIGIPAFVAFALLPPKPLHGSARLARPGEIGKAKLYKAGAHSILLGRHRGNLLAFNGDLHPFLAAATGTGKGVGFVVPNLLHWQGSAIVLDIKGENYSLTSGYRGRALGQRVFRFDPLEELGRTHGFNVLDYVRDGDLRVTDVQTVASILVPNESHDPYWDNVARDLLIGLTLLALEAGPAMGWPVTIGQVHRLLRSEEESGEYLQALLEELAGRGIEISSLCKRYVLSFCNEPEKPRGSIKSALATKLTLWANPLIDRATSHSDFDLRRFRREPQSLYIAIAPDDLQRLAPLVRLLIEFFLSSNTKAGETPADDQGLSVPVLMLLDEFLSLGRVDKLVHALSYVRGWGIRIATVIQSEAQLQAVYGRELAEAFIDNHRARVYYRPPVHRRDLAEAISKIVGQKTVNQTSFGYGDGRRSKQVSKTGQSILDADEIANLSDDETIVLVEGVRPLVGKKLRYYRDKTFKRRQLQALPLPAPLDIELQDAPRVTIQRENEAEEGAENTIEPAESPERAQPNRYTSAGAVRTAINEIPVPRGQPSPEELEQMAQALAEITYYADPEALAAFAEAA
>NC_019941.1|WP_015282532.1|55546_56623_+|P-type-DNA-transfer-ATPase-VirB11
MAGEHAAHALLHDILGPIRPILAREDVTDLCINGPGLLFVEDAHGWERIPADNLTGTWLSGFAKAVASYMSASIGERSPILSGHLPTGERIQIVLPPASEEPSITIRRPSHVTFSLDELAEKGAFDLIAPHLEKKRTVGKEGAGQGGSIEAVGHRESVRCRLAGWNAEDQASVPGILREIVAHRLNVIISGATGSGKTTLSKAMIAEIPLEERLIAIEDAKELQFPHANTVRLFFSRDGAGVSPVTVKDLLVSCLRMKPDRIMLAELRDDETYFYLRNVGSGHPGSITTIHANSAAAAVEQLMLMVRQSSAGAGLTREDIRGLVFHLVDVIIQMERKRVTEIRFLPEASEGARERLPC
>NC_019941.1|WP_015282531.1|54387_55557_+|type-IV-secretion-system-protein-VirB10
MTGVEATADQGFDQIVERGDVPIARAASPLWKWAFIGTMVTLGVGALAAVFYAELSDPAPVEEGEERRPRLRFNVGDYEVPTFDPPVPEPVVEPAHVEVPEPPVMPYIPEIPPPEPRAGYPIPELPRPIPLEPESEIEPVETPEEIARKRRLAAPLGGSGGSISSVGSEAGEGAERNRGGLDLSVTRAATATARRLSDMTFLLPKGTYIGCILDTAIQSDQAGMVGCTLPRDVYGADGTVVLLDRGSQVLGEYRSATLSYGKRRIFVVWDRVRTPEGVIVDIASPGTGPLGRSGMGGKVDNHYWERVGIPVLMSAVSFGVQSYAREQLTSDQSRFIESTTTDSLSTVLAEFAKIKPTLHRNQGDPINILVARDVDLAPVYQLRRRSDGR
>NC_019941.1|WP_015282530.1|53578_54391_+|TrbG/VirB9-family-P-type-conjugative-transfer-protein
MSRIALLYRWAAPMTAAGIALALLVPASCMAATYPKASGVDGRLRYTSYHPDQVYNLQAAIGRALFIQFADGEEMEKFYTGDSDAWEVGKHANMIAIKPTAEIPDTNLIVSTSAGRVYTFDLSLNDRAPMYGIRFSYPEEQHQASETARAKRELSASLDPHAQTRKNFRYAGAGSRAVQPSEVFDNGTHTFMRFPENTIFPSVFAIGPDGGETLVNKTVRGNWLILPAVGREWRLRSGKAVMCVRNDAFAPSGIDNPGETTSRAIERAAR
>NC_019941.1|WP_015282529.1|52934_53582_+|type-IV-secretory-pathway,-component-VirB8
MERFLDWDYDANEAARRQARIAWVVAALCLLLALASVVAVTVLAPLKTVEPVFVRVDSATGAVDVLHRIDEEVGIGRQDLLDKGYLARYVRAREGYFFPTVQEQYRRVMLMSVGDARASYVQGFSKDNPDAPVNLYQDHKTVEVTIKSISFLRKGLAQVRYVAALGDGEETRRQHWISTIAYEYEPDASIPLSVLADNALGFAVTDYRAEPEDAQ
>NC_019941.1|WP_015282528.1|52708_52900_+|hypothetical-protein
MQYPRPLLTALLALLLPALLGACSTVPKAPKCDQSAYRSLNPAHYDPVKESTRADVPFLLPEA
>NC_019941.1|WP_015282527.1|51594_52707_+|type-IV-secretion-system-protein
MDVFTSLFEALDEVLGDYVNEAITAATGYVSGPIAVLGTISFIAMGAVLLRGMSEIPLAKFVQTAALLALVFALAGTAGHYNTYLADHLRSFPDELLATFAGTALGNDAAIGAVLDRIGDQAMTGISAIWSAGGFTDPGPSLFAAVLFVIFLIFGVAAVVALATAKIGLSLVVAVGPLMILGLLFQSTREYFTKWLSYGIQFAFLAMFVGGIAGMADAIVDTYIDALDDSAENVDLVALMAPALMLLLLAKIFAELPHMASSLSGGIGLAVGNTAWRGIQGAMHQAGGKHIDAWRDAARWRRVGRAEALHNRMVETRKAVVDRLVNGAPRVSRADANRPASLSGASAANRDLDREARDHVEARRRRRAGG
>NC_019941.1|WP_015282526.1|51150_51588_+|hypothetical-protein
MKRATALLALGLPVVANAWTVEGVDMDAVPWAELCPSIEAVELTTGAGSCATVHPASHRHAKWDGFDMGVKEPSLNCRKLEREYQRFTSPRPGTTEATKPRDRWGTCIGAFSRALKLRAEEPGRFSEPLDTWRQRYFEGYIHREG
>NC_019941.1|WP_015282537.1|62173_63169_+|tyrosine-type-recombinase/integrase
MANELVSAKSGVLTASGDARGLPSLIVRAGGGAERRYLEFFAAQIRNRNTREAYLRAVRDFLDWAETEARIEDLLDIEPLHVAAWVEIKTQTYEAQSVKQQLAALRHLFDWLVTGHVLHTNPASFVRGPKFSYTKGKTPILTPTEARKLIRSIPTDTLVGLRDRALIGLMIYTFARVSAAVTMNVKDVYRKQESLWVRLHEKGGKHHEMPCQHNLKEWLQEYIEAAGIAEDLNGPLFRTVDRKTKQLGANRLDRQRAWAMVKRRAKKAGIDTPGICNHTFRGTGITAYLENPEAKLEHAQQMAAHSDPKTTRLYDRRSDQVSLDEVERIGI
>NC_019941.1|WP_157633897.1|63208_63859_-|AAA-family-ATPase
MEQRQPGPRPVLLWHQKGGTGKTTLAVGCAAALAGLGRRVLLLDLDPQANAAAWGERFADALGVQVRCDSGLDLARRLGVDGPGLGAGFDDVLVDCPPTIGEHTLDIITAGDLLLIPARPAWPDIWALERVAVLLDDLRTRGDAPRATVIFNQVRDEDLHPFQAGAAELGFNVSEIAIPADAAWPALFTGGLPPPLIRTLLMEISPHLRPVCSADA
>NC_019941.1|WP_015282539.1|63910_64438_-|3'-5'-exonuclease
MRTVFLDLETTGLDPRTDEIVEIGILDEDSQILLDTLVRPVRHRSWPGAQRFHGIAPADVQDAPTHEALRPRIIEAVSDALVVIYNAPFDAGFLRFELEASAEVRCAMREFAEVFGEWSDWHGNYRWQKLHVAAAYVGFDWDGASHRAINDCQATRAVWRYLRDPTERAKRDART
>NC_019941.1|WP_015282540.1|64569_64812_+|WGR-domain-containing-protein
MTPSATQRSWINPEKARYYQVFLDQDLFGDWTLIKVWGGIGSNHGRMHSSGVASYEAGIELVDEIARRRTRRGYRSAPTD
>NC_019941.1|WP_015279036.1|65417_67007_-|IS66-family-transposase
MTSAACDIADAPPEWPAERTELLARIAQLEQQLAWFQRQIFGEKSERRLLLPPPGQLSLGEGFTTPGAAPASDTPVSAHRRRTSRDTPEKEDEDEEALFFDSARVPVEVIAVPNPATDGLAPEDYEVIGEKVSYRLAQRPGSYVILKYVRPLIKRKDDQRLHCPPAPAGVLEGGRADVSFLAGLVIDKFLYHLPLYRQHQRLSAAGIEVSRAWLTQQVLAAALLLTPIVAAQLSGIRAARVKAMDETPIKAGRQGPGKLKKGYFWPIWGDTDEGGGGDIVFLYRPSRAARHVREGLGEHRVAGEVLISDGYSAYARYAERVGLTHAQCWAHTRRTFERAKEIEPAAVAEALDLIGAFYACERAIRKQGLRGEAKRDYRLTHAKPVVEGFFAWAEEQVERAALLPSNPLTKALHYALQRREALSVYLDDPDVPIDTNHLERALRPIPMGRKNWLFCWTEVGAEAVATLQSLIVTCQLHDIDPYVYLVDVLQRIDQHPAAEVHRLIPRLWKQQFAENLLRSDLSRSVPATQ
>NC_019941.1|WP_015279037.1|67016_67379_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MFFPEGRVRVFLHGRPVDMRKSFTGLIALTQQALAQDPLSGHLFVFVNRRGDYLKVLYWDRSGFCLWCKRLERGRFISDWRKRQDQELDVTGLRLLLEGIEPARRRLRYAREGEKRTAIW
>NC_019941.1|WP_015279038.1|67378_67681_-|IS66-family-insertion-sequence-hypothetical-protein
MATTTRVRRTHADWQAVISRAERSSLSTAAFCAGEGISTASFYLWRKRWRASNPPQGDVGEEAPEFLDLGLLSRPANTEGASWDLELDLGDGVVLRLRRA
>NC_019941.1|WP_015282542.1|67695_68994_+|Retron-type-reverse-transcriptase
MIDDSSHCPHRARAEKNASPLPVTDGKFDFVHEDAYLPPGADRQDRKIFEKQQEQHFRAIHRKVLQDRWIFSPFLEKSIPKIAGGERIISLATIRDTLVQRRLYEYLYPIVDPLLSDACCAYRRGSGAHNAIKQIRNALDAGYVHVLDADIKSFFDRVDHETLLAIARDLPIDERALRLLQIYLTTPRVTSEDRRKADSAKPRTKYSREPRTLGIPQGGVISGMLANLLLASFDKEMQQGEDILVRYADDFLVCCQTEQAANDADVRAAHALDALGGLELHPDKTAVRDATDGVDFVGFRIGRGFTRVRSANLAKFKKGIREVIDTHKPKTDSNWDLRRLSRRLSYKIQGPIDEIRKHNLAKHPHHRSWIGFYRIVDDEKQIKNLDRWIREQISRYVWQQHHKKVTAKHMREAGLPSLYGTLWKARKPPESA
>NC_019941.1|WP_015282543.1|69179_70223_-|hypothetical-protein
MRVEPSAPSARPREILATFGRAYPHLWSAVDRLRAMRADDFPEWPDWCFLPMQGAYAILSGGGDRRVPLDRIHHVGIVAALAAWRVTQGVYLFDPAVAEAVAATPLDGELPTDLLYRLPEWCVYIETPDRTWEGRALHGFWAHVEWEEGDGANELRLVLDTAETPDLALDPVRGLIPVPLILGEGSLADALDRLAASSRRRLEAMGLQNLAMPPSAPSRLLGETQPLVALVLYLCAENAEIGDGTRRPSVPVPKRTKRGPRLFPPDRLTAWDVGLRLGAALRRAESSDEPGVEQGERARPRAHIRRAHWHTFRVGEGRRGYKVKWMAPTPVNVRDPEALPATLRPVS
>NC_019941.1|WP_015282544.1|70219_70564_-|hypothetical-protein
MTEGPLHAKLDPQRFPNMSLPMAAILGFVLERQYTTPALADVQVTPDGHVLGWPSEEECVGHSMHLGVEADLRANLSRLGMAAGLDQQEWTLFAAMVRSQLGIELGELAGKGGS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_019941_1	1.1\|44539\|29\|NC_019941\|PILER-CR	44539-44567	29	NC_019941	Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence	44535-44563	0	1.0
NC_019941_1	1.2\|44589\|46\|NC_019941\|PILER-CR	44589-44634	46	NC_019941	Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence	44585-44630	0	1.0
NC_019941_2	2.1\|60576\|54\|NC_019941\|CRT	60576-60629	54	NC_019941	Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence	60576-60629	0	1.0
NC_019941_2	2.3\|60765\|54\|NC_019941\|CRT	60765-60818	54	NC_019941	Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence	60765-60818	0	1.0
NC_019941_2	2.4\|60855\|54\|NC_019941\|CRT	60855-60908	54	NC_019941	Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence	60855-60908	0	1.0
NC_019941_2	2.1\|60576\|54\|NC_019941\|CRT	60576-60629	54	NC_019941	Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence	60765-60818	1	0.981
NC_019941_2	2.3\|60765\|54\|NC_019941\|CRT	60765-60818	54	NC_019941	Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence	60576-60629	1	0.981
NC_019941_2	2.2\|60666\|63\|NC_019941\|CRT	60666-60728	63	NC_019941	Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence	60666-60728	3	0.952
NC_019941_1	1.1\|44539\|29\|NC_019941\|PILER-CR	44539-44567	29	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	810742-810770	8	0.724

1. spacer 1.1|44539|29|NC_019941|PILER-CR matches to NC_019941 (Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence) position: , mismatch: 0, identity: 1.0

ccggggctctggggccgacctgaggctcc	CRISPR spacer
ccggggctctggggccgacctgaggctcc	Protospacer
*****************************

2. spacer 1.2|44589|46|NC_019941|PILER-CR matches to NC_019941 (Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence) position: , mismatch: 0, identity: 1.0

tccggcccaggtcggcctgttctgctacagaaatatggtcctcccg	CRISPR spacer
tccggcccaggtcggcctgttctgctacagaaatatggtcctcccg	Protospacer
**********************************************

3. spacer 2.1|60576|54|NC_019941|CRT matches to NC_019941 (Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence) position: , mismatch: 0, identity: 1.0

agaccgtgcgtgcgtccgccgcggatgcgcttggagagattggcctccctgccg	CRISPR spacer
agaccgtgcgtgcgtccgccgcggatgcgcttggagagattggcctccctgccg	Protospacer
******************************************************

4. spacer 2.3|60765|54|NC_019941|CRT matches to NC_019941 (Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence) position: , mismatch: 0, identity: 1.0

ataccgtgcgtgcgtccgccgcggatgcgcttggagagattggcctccctgccg	CRISPR spacer
ataccgtgcgtgcgtccgccgcggatgcgcttggagagattggcctccctgccg	Protospacer
******************************************************

5. spacer 2.4|60855|54|NC_019941|CRT matches to NC_019941 (Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence) position: , mismatch: 0, identity: 1.0

gggaggtgcgcgcgttcgccacccgcgcgcttggagagattggcacccctgctg	CRISPR spacer
gggaggtgcgcgcgttcgccacccgcgcgcttggagagattggcacccctgctg	Protospacer
******************************************************

6. spacer 2.1|60576|54|NC_019941|CRT matches to NC_019941 (Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence) position: , mismatch: 1, identity: 0.981

agaccgtgcgtgcgtccgccgcggatgcgcttggagagattggcctccctgccg	CRISPR spacer
ataccgtgcgtgcgtccgccgcggatgcgcttggagagattggcctccctgccg	Protospacer
* ****************************************************

7. spacer 2.3|60765|54|NC_019941|CRT matches to NC_019941 (Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence) position: , mismatch: 1, identity: 0.981

ataccgtgcgtgcgtccgccgcggatgcgcttggagagattggcctccctgccg	CRISPR spacer
agaccgtgcgtgcgtccgccgcggatgcgcttggagagattggcctccctgccg	Protospacer
* ****************************************************

8. spacer 2.2|60666|63|NC_019941|CRT matches to NC_019941 (Thioflavicoccus mobilis 8321 plasmid pTHIMO01, complete sequence) position: , mismatch: 3, identity: 0.952

gggaggtgcgcgagcgcgccgccgaagcgcttgaaaagatcgggcccgctgccagccagg	CRISPR spacer
gggaggtgcgcgagcgcgccgccgaagcgcttgaaaagatcgggcccgctgccagccagg	Protospacer
************************************************************

9. spacer 1.1|44539|29|NC_019941|PILER-CR matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.724

ccggggctctggggccgacctgaggctcc	CRISPR spacer
atggggcgctggggccgaccggaggagat	Protospacer
 .***** ************ ****   .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

63208 : 70223

Leptospira_phage(33.33%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157633897.1\|63208_63859_-	AAA family ATPase	A0A2H4JGZ2	uncultured_Caudovirales_phage	4.4e-15	39.3
WP_015282539.1\|63910_64438_-	3'-5' exonuclease	A0A1D9C9N8	Salinivibrio_phage	2.6e-18	38.9
WP_015282540.1\|64569_64812_+	WGR domain-containing protein	NA	NA	NA	NA
WP_015279036.1\|65417_67007_-\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	3.2e-43	29.2
WP_015279037.1\|67016_67379_-	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	2.7e-14	37.7
WP_015279038.1\|67378_67681_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_015282542.1\|67695_68994_+	Retron-type reverse transcriptase	A0A0C5K882	ANMV-1_virus	1.6e-19	25.5
WP_015282543.1\|69179_70223_-	hypothetical protein	S5WA20	Leptospira_phage	9.2e-23	29.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_019940

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_019940_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019940_1

349566-350309

TypeIII

Consensus_repeat	Method
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	PILER-CR
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	CRISPRCasFinder
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	CRT
GGGCCTGACGCTTACCTGATGAAGAAGGTATTGAGACG	PILER-CR

10 spacers

csx1,cas10,cmr3gr5,cmr4gr7,cmr5gr11,cmr6gr7,cas2,cas1,RT

The CRISPR arrays of NC_019940_1

>merge|NC_019940|1|349566-350309|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGACGGGCATCGAACGTCCCCTTCTCGCACCGCAGGGCGGCCTGACGCTTACCTGATGAAGAAGGTATTGAGACGCATACGCATGCTCGTTATCTGCAATGCGAATCGGCCTGACGCTTACCTGATGAAGAAGGTATTGAGACCTCAACAAAATCCAGTATTCCTCAGAGCCTCTGGCCTGACGCTTACCTGATGAAGAAGGTATTGAGACCTAATCTCCGCGATCCCATTCCGCCGGATAACCGGCCTGACGCTTACCTGATGAAGAAGGTATTGAGACAATCCCGTTGATCCGATGAGCAAAGCAAAGGGGGCCTGACGCTTACCTGATGAAGAAGGTATTGAGACTCATCAGGAAGAAAAGATAGAGTGCGCTTCCTCCGGCCTGACGCTTACCTGATGAAGAAGGTATTGAGACCCGCCAAGAACTCCGATGAATATTACGTAAGGGGCCTGACGCTTACCTGATGAAGAAGGTATTGAGACCTCGACCGAGAGTCGGGAACATCAAGCCGATTAGGCCTGACGCTTACCTGATGAAGAAGGTATTGAGACAGATCAGCCCTCCGGAGATCAGCCCTCCAGAGATCAGCCCTCCAGAGAGCGGGCCTGACGTTTGCCTGATGAAGAAGGTATTGAGACGTCAGAGCGAATGCGTTTCGATCAGGGTCTGGAGTGCCTGACGCTTACCTGATGAAGAAGGTATTGAGGC

>NC_019940|1|1|349566-350083|PILER-CR
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	GGGCATCGAACGTCCCCTTCTCGCACCGCAGGGC
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	GCATACGCATGCTCGTTATCTGCAATGCGAATC
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	CTCAACAAAATCCAGTATTCCTCAGAGCCTCT
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	CTAATCTCCGCGATCCCATTCCGCCGGATAACC
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	AATCCCGTTGATCCGATGAGCAAAGCAAAGGG
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	TCATCAGGAAGAAAAGATAGAGTGCGCTTCCTCC
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	CCGCCAAGAACTCCGATGAATATTACGTAAGG
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGACCTCGACCGAGAGTCGGGAACATCAAGCCGATTAGGCCTGACGCTTACCTGATGAAGAAGGTATTGAGACAGATCA	GCCCTCCGGAGATCAGCCCTCCAGAGATCAGCCCTCCAGAGAGCGGGC
CTGACGTTTGCCTGATGAAGAAGGTATTGAGACGTCAGAGCG	AATGCGTTTCGATCAGGGTCTGGAGTGCCTGA


>NC_019940|1|1|349566-350309|CRISPRCasFinder
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	GGGCATCGAACGTCCCCTTCTCGCACCGCAGGGC
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	GCATACGCATGCTCGTTATCTGCAATGCGAATC
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	CTCAACAAAATCCAGTATTCCTCAGAGCCTCT
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	CTAATCTCCGCGATCCCATTCCGCCGGATAACC
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	AATCCCGTTGATCCGATGAGCAAAGCAAAGGG
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	TCATCAGGAAGAAAAGATAGAGTGCGCTTCCTCC
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	CCGCCAAGAACTCCGATGAATATTACGTAAGG
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	CTCGACCGAGAGTCGGGAACATCAAGCCGATTA
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	AGATCAGCCCTCCGGAGATCAGCCCTCCAGAGATCAGCCCTCCAGAGAGCG
GGCCTGACGTTTGCCTGATGAAGAAGGTATTGAGAC	GTCAGAGCGAATGCGTTTCGATCAGGGTCTGGAG
TGCCTGACGCTTACCTGATGAAGAAGGTATTGAGGC

>NC_019940|1|1|349566-350309|CRT
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	GGGCATCGAACGTCCCCTTCTCGCACCGCAGGGC
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	GCATACGCATGCTCGTTATCTGCAATGCGAATC
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	CTCAACAAAATCCAGTATTCCTCAGAGCCTCT
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	CTAATCTCCGCGATCCCATTCCGCCGGATAACC
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	AATCCCGTTGATCCGATGAGCAAAGCAAAGGG
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	TCATCAGGAAGAAAAGATAGAGTGCGCTTCCTCC
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	CCGCCAAGAACTCCGATGAATATTACGTAAGG
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	CTCGACCGAGAGTCGGGAACATCAAGCCGATTA
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	AGATCAGCCCTCCGGAGATCAGCCCTCCAGAGATCAGCCCTCCAGAGAGCG
GGCCTGACGTTTGCCTGATGAAGAAGGTATTGAGAC	GTCAGAGCGAATGCGTTTCGATCAGGGTCTGGAG
TGCCTGACGCTTACCTGATGAAGAAGGTATTGAGGC

>NC_019940|1|2|350117-350308|PILER-CR
	GGGCATCGAACGTCCCCTTCTCGCACCGCAGGGC
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	GCATACGCATGCTCGTTATCTGCAATGCGAATC
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	CTCAACAAAATCCAGTATTCCTCAGAGCCTCT
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	CTAATCTCCGCGATCCCATTCCGCCGGATAACC
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	AATCCCGTTGATCCGATGAGCAAAGCAAAGGG
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	TCATCAGGAAGAAAAGATAGAGTGCGCTTCCTCC
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGAC	CCGCCAAGAACTCCGATGAATATTACGTAAGG
GGCCTGACGCTTACCTGATGAAGAAGGTATTGAGACCTCGACCGAGAGTCGGGAACATCAAGCCGATTAGGCCTGACGCTTACCTGATGAAGAAGGTATTGAGACAGATCA	GCCCTCCGGAGATCAGCCCTCCAGAGATCAGCCCTCCAGAGAGCGGGC
CTGACGTTTGCCTGATGAAGAAGGTATTGAGACGTCAGAGCG	AATGCGTTTCGATCAGGGTCTGGAGTGCCTGA
CGCTTACCTGATGAAGAAGGTATTGAGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019940.1\|WP_157633619.1\|333835_336910_-\|SAVED-domain-containing-protein	unknown	unknown	gnl\|CDD\|380122
NC_019940.1\|WP_015279335.1\|340979_341456_-\|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	gnl\|CDD\|187785
NC_019940.1\|WP_015279342.1\|350751_351873_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224486
NC_019940.1\|WP_157633620.1\|337255_337711_+\|hypothetical-protein	unknown	unknown	unknown
NC_019940.1\|WP_015279341.1\|348443_349247_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|312526
NC_019940.1\|WP_157633809.1\|354400_355213_+\|Retron-type-reverse-transcriptase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_019940.1\|WP_015279344.1\|352693_352978_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_019940.1\|WP_015279350.1\|359445_359934_+\|peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|238901
NC_019940.1\|WP_015279346.1\|353378_354377_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_019940.1\|WP_157633621.1\|337845_339699_-\|SIR2-family-protein	unknown	unknown	gnl\|CDD\|379106
NC_019940.1\|WP_015279345.1\|353040_353382_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NC_019940.1\|WP_015279343.1\|352078_352636_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234714
NC_019940.1\|WP_015279337.1\|342526_343930_-\|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl\|CDD\|370625
NC_019940.1\|WP_015279336.1\|341452_342463_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl\|CDD\|274210
NC_019940.1\|WP_015279349.1\|357861_359259_-\|cysteine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234705
NC_019940.1\|WP_157633622.1\|339720_340887_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	cd09661_cmr6gr7_CAS-III-B	gnl\|CDD\|213662
NC_019940.1\|WP_015279348.1\|357189_357750_-\|transposase	unknown	unknown	gnl\|CDD\|224854
NC_019940.1\|WP_015279351.1\|359956_360718_+\|UDP-2,3-diacylglucosamine-diphosphatase	unknown	unknown	gnl\|CDD\|235420
NC_019940.1\|WP_172637449.1\|343926_346173_-\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl\|CDD\|187810
NC_019940.1\|WP_015279340.1\|347490_347808_-\|CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	gnl\|CDD\|274214

Protein	Function_ID	Function_description	E-value
NC_019940.1\|WP_157633619.1\|333835_336910_-\|SAVED-domain-containing-protein	gnl\|CDD\|380122	pfam18145, SAVED, SMODS-associated and fused to various effectors sensor domain. Predicted to function as a sensor domain, sensing nucleotides or nucleotide derivatives generated by SMODS and other nucleotide synthetase domains. The sensing of ligands by SAVED is predicted to activate effectors deployed by a class of conflict systems which are reliant on the on the production and sensing of the nucleotide second messengers.	8.8254e-23
NC_019940.1\|WP_015279335.1\|340979_341456_-\|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl\|CDD\|187785	cd09654, Cmr5_III-B, CRISPR/Cas system-associated protein Cmr5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-B.	9.47233e-07
NC_019940.1\|WP_015279342.1\|350751_351873_+\|hypothetical-protein	gnl\|CDD\|224486	COG1570, XseA, Exonuclease VII, large subunit [DNA replication, recombination, and repair].	0.00139372
NC_019940.1\|WP_015279337.1\|342526_343930_-\|CRISPR-associated-protein-Cmr3	gnl\|CDD\|370625	pfam09700, Cas_Cmr3, CRISPR-associated protein (Cas_Cmr3). CRISPR is a term for Clustered Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This highly divergent family, found in at least ten different archaeal and bacterial species, is represented by TM1793 from Thermotoga maritima.	7.48223e-31
NC_019940.1\|WP_015279341.1\|348443_349247_+\|hypothetical-protein	gnl\|CDD\|312526	pfam09002, DUF1887, Domain of unknown function (DUF1887). This domain is found in a set of hypothetical bacterial proteins.	0.00848567
NC_019940.1\|WP_157633809.1\|354400_355213_+\|Retron-type-reverse-transcriptase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	1.45329e-75
NC_019940.1\|WP_015279344.1\|352693_352978_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.67245e-12
NC_019940.1\|WP_015279350.1\|359445_359934_+\|peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|238901	cd01920, cyclophilin_EcCYP_like, cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these have reduced affinity for cyclosporin A. E. coli cyclophilin A has a similar peptidylprolyl cis- trans isomerase activity to the human cyclophilin A. Most members of this subfamily contain a phenylalanine residue at the position equivalent to Human cyclophilin W121, where a tyrptophan has been shown to be important for cyclophilin binding.	5.43754e-81
NC_019940.1\|WP_157633621.1\|337845_339699_-\|SIR2-family-protein	gnl\|CDD\|379106	pfam13289, SIR2_2, SIR2-like domain. This family of proteins are related to the sirtuins.	0.000489792
NC_019940.1\|WP_015279345.1\|353040_353382_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.4403e-13
NC_019940.1\|WP_015279343.1\|352078_352636_+\|hypothetical-protein	gnl\|CDD\|234714	PRK00286, xseA, exodeoxyribonuclease VII large subunit; Reviewed.	0.00337628
NC_019940.1\|WP_015279346.1\|353378_354377_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	9.1117e-72
NC_019940.1\|WP_015279336.1\|341452_342463_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	1.05871e-54
NC_019940.1\|WP_015279349.1\|357861_359259_-\|cysteine--tRNA-ligase	gnl\|CDD\|234705	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated.	0
NC_019940.1\|WP_157633622.1\|339720_340887_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl\|CDD\|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	8.44796e-30
NC_019940.1\|WP_015279348.1\|357189_357750_-\|transposase	gnl\|CDD\|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.38803e-29
NC_019940.1\|WP_015279351.1\|359956_360718_+\|UDP-2,3-diacylglucosamine-diphosphatase	gnl\|CDD\|235420	PRK05340, PRK05340, UDP-2,3-diacylglucosamine hydrolase; Provisional.	2.68191e-113
NC_019940.1\|WP_172637449.1\|343926_346173_-\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.71799e-43
NC_019940.1\|WP_015279340.1\|347490_347808_-\|CRISPR-associated-protein	gnl\|CDD\|274214	TIGR02584, hypothetical_protein_NE0113, CRISPR-associated protein, NE0113 family. Members of this minor CRISPR-associated (Cas) protein family are found in cas gene clusters in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, Mannheimia succiniciproducens MBEL55E, and Verrucomicrobium spinosum.	1.4723e-14

>NC_019940.1|WP_015279341.1|348443_349247_+|hypothetical-protein
MTCSPVDLRTGLLVGIGLVTNSLFEWLADIGTWFGGGTVDDWLPVHRLLAVGLFAGELLAVAAYARGARKRYRPRVGVEPQPAQVHGLILFLSNLSAEQARAVQAGLTTLDGLAAFRAAHGGLNWRMPLEAIAHHAPRLQHVIVICSAGRTGSAGQWPLFRALVQRVFPGAAFELRSAAQLDSRFGAGIDFEDVDGVAQATDDAYVHLLERGLPHSEILIDVTGGQKTNAIAATAVALAEGRRIQYVACDRDTCTCHLNVYDVTYDG
>NC_019940.1|WP_015279340.1|347490_347808_-|CRISPR-associated-protein
MTTPSAGARQSHEYPHRVLLMVTGRTPQVVTETLYALACRPGPGERRFVPTEIHLITTAEGAQDARIALLDPKDGWFQRLCAASSVVRPRFRTRFRGATHASITV
>NC_019940.1|WP_172637449.1|343926_346173_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MAAARPPDGEARAYVGRRRGSITGKGDDSKRRGCAATDREISGCGGARGRRGGCLVQMAREQQGVGAAMTSGTENATAGATDKAFIVAIALGPVGRFIAGGRRSRDLWYGSRLLSELTRQAANSLHENGSTTLYVPLPETLYCDYWSKPHQGPVIPNKILALVKAKDAEQVRDDLDRARKAVLDFLAEEVRKLAEDEKWKIGVDRSALQAQADAIEGGDFVEFYAAWAPLSGDEPAAVERARDVLLAGRKAARVFPAPSWTKPGRPKCSLDPGRDSVMVEENPRAKPRESTRLMMDREQRGIRRDERLDAIGLLRRRAVFEEVVETNRADDGKLCLPKLPFPPLARVAADPWLEGAAANSRHLLEAIVDELKRLDEGRGDRNPLLLISSPCREPAKALDENGPFPYDPSLLFENGIQTMRRELDRRRKSLGNDDPSDGEYLEPCKKAASALREMERPVRQLHDLFGFPSPYYAMLEADGDDMGHLLGELTGERRTRAVEALGEFARHAWDEIDGCHGFAFYVGGDELTAYLPVDKALELVGALSGLFTAEMRASKVWKHDSCPTLSAGVVIAHQKEDMRAVRDRASAALKRAKRHRKHERDRSSTDPSVQGESGWVCIEERPAGGTARTLVGPIDRIRNEQAEWGQLIARAGNDRDLSLATAHGLLEWADRFRTNEAGSGDLGIALAQASVWQRLKRRDQDRGELRWLQRFLAARSWAEIRDYANAILLADRIADIAAQRQPLGRRTR
>NC_019940.1|WP_015279337.1|342526_343930_-|CRISPR-associated-protein-Cmr3
MTRETWYLTPRDPLVLGDGRGPVPFVERKTHPLPLPGTLAGMVRASFVQDRSEVSSAEALALLDIRVGAPWLVRLADPVRGLDGGVEHHYVFAPADARVAATGRLERAAVIALNGGQDGEGVYWPPGFPRLDHLVLLPERSDDGSKYEVPRRLFWPLGALVNWSLGEDPRSDAFECVAEPPRPADGSSPDGDDPHVPTRPEQRTHVGIDDEAQTADPSILFSSAGQRMAPHFSIAVEVDLPPQCPPGPAAHALGVLGGESRLTSIVRRPAAQSGFGFPPFSDWEGRYRHALEAAKDPLGGIRLQLLSHAFLPPQDGDEGWACLPSWLESRRHPRLPEGLYLRLVALCVPGPLAISGWDLQAVAAGTPDNGGRRTHSGGAPREVRRLVPAGSLYYFALEDAQGAPVTEREKWLDACRCLWWELLDPEGPGERTDETRHRAAAGADGHGRILPGLWSPGAAMASGASVR
>NC_019940.1|WP_015279336.1|341452_342463_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MSMNSRDALTTPDTGPRQVAMLYLVRAISPLHVGVGEGLGTINLPTARESLTGYPLVPGSSVKGVLRDHAEYRNLTKEEVWTAFGPDQTQAADARGGLVITDANLLALPVRSLYGTFAWVTCPFILRRFAADAAEAGFDDGVLETFRDLGRDGQQNPRVTDEACRLLAKGEGERLLLEDRPFGGVVRDPGVRAAGAWLAQKLWPNDEDRDLRAFFQARFAVLPDDPFGFFTRTALEVRQRVRIDRQTGTAAASGPWSEELMPAETLLHGLVLGRRTVFVPDGTPNDTRRKGPEDGPGVLRSLLADRPLLRLGGKSSGGSGRVHLRLVEPNGKRSAP
>NC_019940.1|WP_015279335.1|340979_341456_-|type-III-B-CRISPR-module-associated-protein-Cmr5
MISTSGDGFARREHRLVRLIEQRLQGDDSGLVGNARVRGLPEMVRRHGLLQVVAFLRSKGADAAENGSPGKRGSGDCDQQLLDLLQNALQEDLEAVPRSEKGGVCKLAPADLAHLGEDSPTEYLYLNESAIQVAVWIQRLAAARADLDEARQVCGGDG
>NC_019940.1|WP_157633622.1|339720_340887_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MQNLRPDPLPAHVGLWLDRCLFEPKASEDAPDDHPGRRALYASAIEALDPVAEPPALTHYRTLFAAWERLARTDHPGVLGRVCEVRARSRVLLHPNSGASVTDGGILLHHSYGVPYLPGTALKGLCRAFADRLQEETGGKIDSPNGAVLPEGWIDRLFGHLPCQGDRGGEASLCDFWDALWVPPEPGSPGAESPLALDVVNPHHGAYYSKSSPGQDGERVPPKESDPPIPTHRLTIRPGARFLVRIESADDPAFGAWLDWILTALLLPALDNEGIGTRTTSGYGRLVGVDGPAGGGAAGGATPSERDLALISRTRNDGALHATFADGKFATLRGERARQIFQSLSDTVRRRIDRNKPTRLQVVYRKQGNAYTIEDIQETPTPSTPAAT
>NC_019940.1|WP_157633621.1|337845_339699_-|SIR2-family-protein
MDEALAVWLGSQGADDTREVPASGQERVLFLGAGFTKASNGDAPLFNDYCKPIAQRLRGSSRLPVWLAGVVDPSRWPHVTDLVELLDAIEGRRAVIDLLLAEPGYESFSVEPGGFRSYRRPLPPRAESTFRTLEQWQEAVDAAQPTHLAPLDPAGPPVTVGRLIAEGWATRVLTTNWDAYVELGCWLAGLAVHHAGAPVSSEGGPRRVQVYDCPSSVALYPRSAGGVPILKLHGGVNHVERILSLAARGLLTVAEADARLAEAFLVATSDLTHWREASQWVQDAVADALRGSRVLLLGVSGADSVTFRAVRQRIGEWERRAAEWDRDRSSDAHGVDCLEPGPAPLAAVDRYPSPTLGALMKVGRGRGHLRFHILEADARHTLRSAYAWGLLRLMLRHADLDRPGLVSLGADLVERLRTEVNGRARTDEADARTPLIDLLCDALGPGARWAAIAERVAPFESRPMAAESRWWYAPWDPARTGLALDPDNLAQILACAAVLAGIGGPRQAAGLTVDPWGGVVELDERHPCPSMAGCDLLLLPWPWPVRRGLGSADLHAALRNQTAWGLGRPNVSFGSPGVRVVPVAAWSELTPKQRQEIEVPTGWAKLENVDWIEDLNS
>NC_019940.1|WP_157633620.1|337255_337711_+|hypothetical-protein
MRDQRSAQDVRRGQRLAIAIGDPADLDIDGGLAGAPLGPLQGLAQAQETVTRVADQDHLECRTLGQAAFVFSGLAVVAMQQPFQKALATGLLVRLQHEGQERGQGVGNRHLARRLLRRPSLATPFPQTLTEAMDTMELGNRMRLSIQHRAP
>NC_019940.1|WP_157633619.1|333835_336910_-|SAVED-domain-containing-protein
MAEALARLYLGRPRVRLTLPEGGAVWTNEDTLGNGPVVLEAIRIAVAGADAPTRMDLDPAAVLPLFGDDARLDEGSVGETALLSIWPLLVDREDTEKRRDEVPRLADALQDLVRRLEDCAANAANAKEGGPGQSADTVEIDIGPDLGQRFKRYLSEFALRTDKDEDDRDTEPDAHREKIQSLLDRLRTRKKYFPIPADLLFRYLQDCLRQERRRGFTPDWMVLGRIEREFGGHAPWRQLAANVLRERASRQRREASDYWDGIEGVIAASPVIRSLERDLEDYFEVGLSCLYDHPIRSNTARQVRNGQARRLARWLGIGRIDLPVLLLDEPLLGQDLPASAALLGRYLRLRRKAESQRWALACAPPVERDEEALSDSEGTDTPIAALALRHARCEPGPSTRSNSDPPETAIRDLEPAQVEAALPLPPQLIVTSNKPAVLAAAAEADGVVLDRNLRDAVEKLIPSNWRGPVVDALKKANREFADEMRQQAADAWINRLPAQGLRLYWQRPDVLPPVAEPFRYLEDVCEALGPTRLGLEGLRSEVSERVGVIGEGDLSRPVTALADQLLHWLVLTDLLPAALRDGDAHFEISGVATRAIPAAGGRIEEKGPARLRRIGPWLECLPPDPVGGPRPQVPETAPESIDPAQDIESAQAAVPKKPASVAATMGIWYVAVPPEISAKAEDCFSRFAVGMEGVVPPDCRCELEIRRAGMRPYRQGDPDPAVVVAEILTETGRNGEERPTAKVSSAFVSPDWTGELSLLADELARQRVKALLGQLPDDEPVGIGLLTHEEGRGFERSVAFVLEGQQVHTDRPDWEFLTRRLWQQRIEAPLTLLRRALAVDRRAQSLRFHAFCHLGAAIRAGAIFSHTSGFSVECMQNGEPWDLYRQPAYRKQPFNISESGPPAGAAAEIHLLLSFSQTVSEAYQIWREDQAKTLPVRVISIEPQGGAGRQAIAREDVADWGEAVFHVLSTRRTSRIDCTRIFCAAPVALAMAIGRSLNACGRIVTMDLPKPSVRGYFASFDFET
>NC_019940.1|WP_015279342.1|350751_351873_+|hypothetical-protein
MRLTSFFRLGWTVQLFVGVALFSVSFLIELDVMQRLFGTSPAAIVLVGGFELGKAAAIVWHRYLALASSAVYPVQTRVVSAGFRSGLVLLSLLCSLLYLGAQLDRPNLVAVRAAEVARIDARLAEDLRRLETAREARFQTDEARRRTEYEDARAEHQRRIVELEDRLREEMEDRLREEMDNVVGGTFKGPRYLELSERLELTRGERDAALTRLSQRHLREATQLAETLARELAAQRERLTAAAEARRQAVRTATFDDDERVDNPLVTAFLRTTDALSGHQLTPPQFVFGLALFLSALIELGIVLAFDTVTLVAIPALEAQHREDVTTEALMAEVSGNATREGIRHRETMERIRKGAERAMDEAEAHIGPRQAA
>NC_019940.1|WP_015279343.1|352078_352636_+|hypothetical-protein
MSPDNHALTVDLDDLPAEATRRGDDNEQRVDQALRRHTESLLPAMLERGRHRLVREHLDTELALGFEHRRQALSMALESRLQSIREACNHLLVTGKAHLRRQRIEYFGEVYRQLEQRMSQLADDYLAEADTRFARIEGLKSEHLRQREQQRLERSADDFLATLDRLMDDFRAIISENVDHRRSSL
>NC_019940.1|WP_015279344.1|352693_352978_+|CRISPR-associated-endonuclease-Cas2
MARKPAVIAYDIRCDKRRRRAARCLKGWRLDGQYSLIECRLTEAEAQELFLQLVDIIDRDEDALLLAWMDGTRESCPVTRCARIGFRKPALYLD
>NC_019940.1|WP_015279345.1|353040_353382_+|CRISPR-associated-endonuclease-Cas2
MKHWSLIAYDIRDPRRLRRVHLCLRRQALAVQKSVFLIEADERRLAEILAELRRRADNREDDIRLYAIPDPAAIWAAGRQSERVANLYGGAPAEAERPRRGRWLKGLFGREAA
>NC_019940.1|WP_015279346.1|353378_354377_+|CRISPR-associated-endonuclease-Cas1
MILVVDRRDSVLRHDSGVLCLEREGGETRRAPINQLELVVVYGNPLAETAVWRKLAAAGVPTVLLPVRGRDGAAVLGNGLATQLPLRRLQHRRAAEPARALELARWILAQKLASYDLPLQPLRRRHGADEAACAGLLRQRDRTLAALATARSRDELMGLEGQLAHAWFALLAKRLAPAWGFTGRNRRPPQDPINALFSLGYTLLGAEVHQGVVAAGLDPSLGFLHQPVPGREAMVLDLTEPFRSAVDHFVLDWIAVDGPRQADYYYREADGCRLSKTARPGFFQAWASYRHHWPYAVRLDPSADWPASTLREQIRGQIERLRSAMKTPEAPS
>NC_019940.1|WP_157633809.1|354400_355213_+|Retron-type-reverse-transcriptase
MSPEVLDRAWRKLKGEHTPWSPTVSRDDLQHHLMRHLLACREEVLDGAYRPLPLRQFPVRKPDGRQRVLTAQFLRDKLVQRALLTVLEPRAEALFHDDSFAYRPERNVAKALAKVRERVRIGLDWLVDADIEKFFDSIPHRPLLRVLDGFVADAKAMKLIERWLGQGAHVRSLLATPRGIAQGAILSPLFCNLYLHGFDRSLDSAHIPFVRFADDFLLFAPTRSDAGRAMEHAARRLERLDLRLHPDKTRVVRSGREVIFLGETLPGPTR
>NC_019940.1|WP_015279348.1|357189_357750_-|transposase
MADWRRVFEPGGTYCFTLVTERRAPIFADERSRAILRRALEATKARWPFEIVAIVLMPDHLHTLWCLPANDSAYPTRIGWIKKEFTKGWLASGGAEQALSASRLRQRRRGVLQRRFWEHAFRSERDLHRHLDYLHYNPVKHGYVGCPRDWPWSSFHRYCRAGVYTEDWGCTGLDFSDLAKEIGDVD
>NC_019940.1|WP_015279349.1|357861_359259_-|cysteine--tRNA-ligase
MLQIYNSLTRQKAVFTPLVPGQVRMYVCGMTVYDYCHLGHARVMVVFDVVYRYLRHLGYEVTYIRNITDIDDKIIRRAGENDEPIAALTERFIAAMHEDAAALGVLPPSDEPRATAHIDEIQAMVATLLERGLAYRADNGDVYYAVGRFPGYGKLSGKDPQELRAGSRVEIGEAKRDPLDFVLWKAAKPGEPAWESPWGPGRPGWHIECSAMSTCALGAHFDIHGGGADLQFPHHENEIAQSEGATGEPFVEVWMHNGFVRVNDEKMSKSLGNFFTVREILARYRPEEVRYFILTSHYRSPLNYDEDHLQQARGALTRFYTALRGLPPAEPAGGEAFSERFHAAMDDDFATPEALAVLFELVREINRVRADDEARAAALGAELRRLGAVLGILQGDPEAYLRGEGLVVDAGPAALDDAAIDALIERRTAARQARQWAEADRLRDQLQEAGILLEDGPQGTTWRRG
>NC_019940.1|WP_015279350.1|359445_359934_+|peptidyl-prolyl-cis-trans-isomerase
MIKLTTNHGDILIELDPEKAPETCANFTQYVRDGHYDGTLFHRVINGFMIQGGGMDSSFSPLPTRQPIQNEAQNGLKNKTGTVAMARTNDPHSATSQFFINVSDNDFLDYPGQDGWGYCVFGKVTDGMDVVEKIKGVRTTSRRGHQDVPVEDVVIEKAVIVD
>NC_019940.1|WP_015279351.1|359956_360718_+|UDP-2,3-diacylglucosamine-diphosphatase
MARPDTGSGDPAGDGERLFISDLHLAPERPETVARFLDFLAGRARRAERLYILGDLFDAWIGDDDDTQPYPQIRTALRALTDSGTACRLLHGNRDFLIGRAFARDTGCTLLRDPTLIRLRGERVLLMHGDLLCTDDVAYQRFRRRVRNPLVRRLFLWRSLARRRAQAADYRRRSGSATAAKTAASMDVSQPTVARFMRRHVADRLIHGHTHRPADHAFTLDGHPVLRQVLAEWHPERGEVLVADAGGWRREPV

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Crispr_ID: NC_019940_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019940_3

356498-356602

TypeIII

Consensus_repeat	Method
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	CRISPRCasFinder

1 spacers

RT,cas1,cas2,csx1,cas10,cmr3gr5

The CRISPR arrays of NC_019940_3

>merge|NC_019940|3|356498-356602|CRISPRCasFinder
GGTCGAGCACTTACCTGATGAAGAAGGTATTGAGACCCGTCGATGAGACGAGCTTTGGCAACTTTGGCGGGCCTAGCACCTAGCTGATGAAGAGGCGAGCGTAGG

>NC_019940|3|3|356498-356602|CRISPRCasFinder
GGTCGAGCACTTACCTGATGAAGAAGGTATTGAGAC	CCGTCGATGAGACGAGCTTTGGCAACTTTGGCG
GGCCTAGCACCTAGCTGATGAAGAGGCGAGCGTAGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019940.1\|WP_015279356.1\|371050_371533_-\|hypothetical-protein	unknown	unknown	unknown
NC_019940.1\|WP_015279342.1\|350751_351873_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224486
NC_019940.1\|WP_015279341.1\|348443_349247_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|312526
NC_019940.1\|WP_015279337.1\|342526_343930_-\|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl\|CDD\|370625
NC_019940.1\|WP_157633809.1\|354400_355213_+\|Retron-type-reverse-transcriptase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_019940.1\|WP_015279344.1\|352693_352978_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_019940.1\|WP_015279351.1\|359956_360718_+\|UDP-2,3-diacylglucosamine-diphosphatase	unknown	unknown	gnl\|CDD\|235420
NC_019940.1\|WP_015279352.1\|360731_361859_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133062
NC_019940.1\|WP_015279345.1\|353040_353382_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NC_019940.1\|WP_015279343.1\|352078_352636_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234714
NC_019940.1\|WP_015279346.1\|353378_354377_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_019940.1\|WP_157633810.1\|369359_369821_-\|hypothetical-protein	unknown	unknown	unknown
NC_019940.1\|WP_015279349.1\|357861_359259_-\|cysteine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234705
NC_019940.1\|WP_015279350.1\|359445_359934_+\|peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|238901
NC_019940.1\|WP_015279348.1\|357189_357750_-\|transposase	unknown	unknown	gnl\|CDD\|224854
NC_019940.1\|WP_015279357.1\|371808_372105_-\|DUF3096-domain-containing-protein	unknown	unknown	gnl\|CDD\|371454
NC_019940.1\|WP_015279354.1\|363801_369180_+\|RecQ-family-ATP-dependent-DNA-helicase	unknown	unknown	gnl\|CDD\|223588
NC_019940.1\|WP_015279353.1\|361969_363568_+\|glycosyltransferase-family-39-protein	unknown	unknown	gnl\|CDD\|379080
NC_019940.1\|WP_172637449.1\|343926_346173_-\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl\|CDD\|187810
NC_019940.1\|WP_015279340.1\|347490_347808_-\|CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	gnl\|CDD\|274214

Protein	Function_ID	Function_description	E-value
NC_019940.1\|WP_015279342.1\|350751_351873_+\|hypothetical-protein	gnl\|CDD\|224486	COG1570, XseA, Exonuclease VII, large subunit [DNA replication, recombination, and repair].	0.00139372
NC_019940.1\|WP_015279341.1\|348443_349247_+\|hypothetical-protein	gnl\|CDD\|312526	pfam09002, DUF1887, Domain of unknown function (DUF1887). This domain is found in a set of hypothetical bacterial proteins.	0.00848567
NC_019940.1\|WP_015279337.1\|342526_343930_-\|CRISPR-associated-protein-Cmr3	gnl\|CDD\|370625	pfam09700, Cas_Cmr3, CRISPR-associated protein (Cas_Cmr3). CRISPR is a term for Clustered Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This highly divergent family, found in at least ten different archaeal and bacterial species, is represented by TM1793 from Thermotoga maritima.	7.48223e-31
NC_019940.1\|WP_157633809.1\|354400_355213_+\|Retron-type-reverse-transcriptase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	1.45329e-75
NC_019940.1\|WP_015279344.1\|352693_352978_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.67245e-12
NC_019940.1\|WP_015279351.1\|359956_360718_+\|UDP-2,3-diacylglucosamine-diphosphatase	gnl\|CDD\|235420	PRK05340, PRK05340, UDP-2,3-diacylglucosamine hydrolase; Provisional.	2.68191e-113
NC_019940.1\|WP_015279352.1\|360731_361859_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|133062	cd06442, DPM1_like, DPM1_like represents putative enzymes similar to eukaryotic DPM1. Proteins similar to eukaryotic DPM1, including enzymes from bacteria and archaea; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. This protein family belongs to Glycosyltransferase 2 superfamily.	3.09395e-84
NC_019940.1\|WP_015279345.1\|353040_353382_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.4403e-13
NC_019940.1\|WP_015279343.1\|352078_352636_+\|hypothetical-protein	gnl\|CDD\|234714	PRK00286, xseA, exodeoxyribonuclease VII large subunit; Reviewed.	0.00337628
NC_019940.1\|WP_015279346.1\|353378_354377_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	9.1117e-72
NC_019940.1\|WP_015279349.1\|357861_359259_-\|cysteine--tRNA-ligase	gnl\|CDD\|234705	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated.	0
NC_019940.1\|WP_015279350.1\|359445_359934_+\|peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|238901	cd01920, cyclophilin_EcCYP_like, cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these have reduced affinity for cyclosporin A. E. coli cyclophilin A has a similar peptidylprolyl cis- trans isomerase activity to the human cyclophilin A. Most members of this subfamily contain a phenylalanine residue at the position equivalent to Human cyclophilin W121, where a tyrptophan has been shown to be important for cyclophilin binding.	5.43754e-81
NC_019940.1\|WP_015279348.1\|357189_357750_-\|transposase	gnl\|CDD\|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.38803e-29
NC_019940.1\|WP_015279357.1\|371808_372105_-\|DUF3096-domain-containing-protein	gnl\|CDD\|371454	pfam11295, DUF3096, Protein of unknown function (DUF3096). This family of proteins with unknown function appears to be restricted to Proteobacteria.	0.000629287
NC_019940.1\|WP_015279354.1\|363801_369180_+\|RecQ-family-ATP-dependent-DNA-helicase	gnl\|CDD\|223588	COG0514, RecQ, Superfamily II DNA helicase [DNA replication, recombination, and repair].	2.60388e-100
NC_019940.1\|WP_015279353.1\|361969_363568_+\|glycosyltransferase-family-39-protein	gnl\|CDD\|379080	pfam13231, PMT_2, Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.	1.16132e-18
NC_019940.1\|WP_172637449.1\|343926_346173_-\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.71799e-43
NC_019940.1\|WP_015279340.1\|347490_347808_-\|CRISPR-associated-protein	gnl\|CDD\|274214	TIGR02584, hypothetical_protein_NE0113, CRISPR-associated protein, NE0113 family. Members of this minor CRISPR-associated (Cas) protein family are found in cas gene clusters in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, Mannheimia succiniciproducens MBEL55E, and Verrucomicrobium spinosum.	1.4723e-14

>NC_019940.1|WP_157633809.1|354400_355213_+|Retron-type-reverse-transcriptase
MSPEVLDRAWRKLKGEHTPWSPTVSRDDLQHHLMRHLLACREEVLDGAYRPLPLRQFPVRKPDGRQRVLTAQFLRDKLVQRALLTVLEPRAEALFHDDSFAYRPERNVAKALAKVRERVRIGLDWLVDADIEKFFDSIPHRPLLRVLDGFVADAKAMKLIERWLGQGAHVRSLLATPRGIAQGAILSPLFCNLYLHGFDRSLDSAHIPFVRFADDFLLFAPTRSDAGRAMEHAARRLERLDLRLHPDKTRVVRSGREVIFLGETLPGPTR
>NC_019940.1|WP_015279346.1|353378_354377_+|CRISPR-associated-endonuclease-Cas1
MILVVDRRDSVLRHDSGVLCLEREGGETRRAPINQLELVVVYGNPLAETAVWRKLAAAGVPTVLLPVRGRDGAAVLGNGLATQLPLRRLQHRRAAEPARALELARWILAQKLASYDLPLQPLRRRHGADEAACAGLLRQRDRTLAALATARSRDELMGLEGQLAHAWFALLAKRLAPAWGFTGRNRRPPQDPINALFSLGYTLLGAEVHQGVVAAGLDPSLGFLHQPVPGREAMVLDLTEPFRSAVDHFVLDWIAVDGPRQADYYYREADGCRLSKTARPGFFQAWASYRHHWPYAVRLDPSADWPASTLREQIRGQIERLRSAMKTPEAPS
>NC_019940.1|WP_015279345.1|353040_353382_+|CRISPR-associated-endonuclease-Cas2
MKHWSLIAYDIRDPRRLRRVHLCLRRQALAVQKSVFLIEADERRLAEILAELRRRADNREDDIRLYAIPDPAAIWAAGRQSERVANLYGGAPAEAERPRRGRWLKGLFGREAA
>NC_019940.1|WP_015279344.1|352693_352978_+|CRISPR-associated-endonuclease-Cas2
MARKPAVIAYDIRCDKRRRRAARCLKGWRLDGQYSLIECRLTEAEAQELFLQLVDIIDRDEDALLLAWMDGTRESCPVTRCARIGFRKPALYLD
>NC_019940.1|WP_015279343.1|352078_352636_+|hypothetical-protein
MSPDNHALTVDLDDLPAEATRRGDDNEQRVDQALRRHTESLLPAMLERGRHRLVREHLDTELALGFEHRRQALSMALESRLQSIREACNHLLVTGKAHLRRQRIEYFGEVYRQLEQRMSQLADDYLAEADTRFARIEGLKSEHLRQREQQRLERSADDFLATLDRLMDDFRAIISENVDHRRSSL
>NC_019940.1|WP_015279342.1|350751_351873_+|hypothetical-protein
MRLTSFFRLGWTVQLFVGVALFSVSFLIELDVMQRLFGTSPAAIVLVGGFELGKAAAIVWHRYLALASSAVYPVQTRVVSAGFRSGLVLLSLLCSLLYLGAQLDRPNLVAVRAAEVARIDARLAEDLRRLETAREARFQTDEARRRTEYEDARAEHQRRIVELEDRLREEMEDRLREEMDNVVGGTFKGPRYLELSERLELTRGERDAALTRLSQRHLREATQLAETLARELAAQRERLTAAAEARRQAVRTATFDDDERVDNPLVTAFLRTTDALSGHQLTPPQFVFGLALFLSALIELGIVLAFDTVTLVAIPALEAQHREDVTTEALMAEVSGNATREGIRHRETMERIRKGAERAMDEAEAHIGPRQAA
>NC_019940.1|WP_015279341.1|348443_349247_+|hypothetical-protein
MTCSPVDLRTGLLVGIGLVTNSLFEWLADIGTWFGGGTVDDWLPVHRLLAVGLFAGELLAVAAYARGARKRYRPRVGVEPQPAQVHGLILFLSNLSAEQARAVQAGLTTLDGLAAFRAAHGGLNWRMPLEAIAHHAPRLQHVIVICSAGRTGSAGQWPLFRALVQRVFPGAAFELRSAAQLDSRFGAGIDFEDVDGVAQATDDAYVHLLERGLPHSEILIDVTGGQKTNAIAATAVALAEGRRIQYVACDRDTCTCHLNVYDVTYDG
>NC_019940.1|WP_015279340.1|347490_347808_-|CRISPR-associated-protein
MTTPSAGARQSHEYPHRVLLMVTGRTPQVVTETLYALACRPGPGERRFVPTEIHLITTAEGAQDARIALLDPKDGWFQRLCAASSVVRPRFRTRFRGATHASITV
>NC_019940.1|WP_172637449.1|343926_346173_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MAAARPPDGEARAYVGRRRGSITGKGDDSKRRGCAATDREISGCGGARGRRGGCLVQMAREQQGVGAAMTSGTENATAGATDKAFIVAIALGPVGRFIAGGRRSRDLWYGSRLLSELTRQAANSLHENGSTTLYVPLPETLYCDYWSKPHQGPVIPNKILALVKAKDAEQVRDDLDRARKAVLDFLAEEVRKLAEDEKWKIGVDRSALQAQADAIEGGDFVEFYAAWAPLSGDEPAAVERARDVLLAGRKAARVFPAPSWTKPGRPKCSLDPGRDSVMVEENPRAKPRESTRLMMDREQRGIRRDERLDAIGLLRRRAVFEEVVETNRADDGKLCLPKLPFPPLARVAADPWLEGAAANSRHLLEAIVDELKRLDEGRGDRNPLLLISSPCREPAKALDENGPFPYDPSLLFENGIQTMRRELDRRRKSLGNDDPSDGEYLEPCKKAASALREMERPVRQLHDLFGFPSPYYAMLEADGDDMGHLLGELTGERRTRAVEALGEFARHAWDEIDGCHGFAFYVGGDELTAYLPVDKALELVGALSGLFTAEMRASKVWKHDSCPTLSAGVVIAHQKEDMRAVRDRASAALKRAKRHRKHERDRSSTDPSVQGESGWVCIEERPAGGTARTLVGPIDRIRNEQAEWGQLIARAGNDRDLSLATAHGLLEWADRFRTNEAGSGDLGIALAQASVWQRLKRRDQDRGELRWLQRFLAARSWAEIRDYANAILLADRIADIAAQRQPLGRRTR
>NC_019940.1|WP_015279337.1|342526_343930_-|CRISPR-associated-protein-Cmr3
MTRETWYLTPRDPLVLGDGRGPVPFVERKTHPLPLPGTLAGMVRASFVQDRSEVSSAEALALLDIRVGAPWLVRLADPVRGLDGGVEHHYVFAPADARVAATGRLERAAVIALNGGQDGEGVYWPPGFPRLDHLVLLPERSDDGSKYEVPRRLFWPLGALVNWSLGEDPRSDAFECVAEPPRPADGSSPDGDDPHVPTRPEQRTHVGIDDEAQTADPSILFSSAGQRMAPHFSIAVEVDLPPQCPPGPAAHALGVLGGESRLTSIVRRPAAQSGFGFPPFSDWEGRYRHALEAAKDPLGGIRLQLLSHAFLPPQDGDEGWACLPSWLESRRHPRLPEGLYLRLVALCVPGPLAISGWDLQAVAAGTPDNGGRRTHSGGAPREVRRLVPAGSLYYFALEDAQGAPVTEREKWLDACRCLWWELLDPEGPGERTDETRHRAAAGADGHGRILPGLWSPGAAMASGASVR
>NC_019940.1|WP_015279348.1|357189_357750_-|transposase
MADWRRVFEPGGTYCFTLVTERRAPIFADERSRAILRRALEATKARWPFEIVAIVLMPDHLHTLWCLPANDSAYPTRIGWIKKEFTKGWLASGGAEQALSASRLRQRRRGVLQRRFWEHAFRSERDLHRHLDYLHYNPVKHGYVGCPRDWPWSSFHRYCRAGVYTEDWGCTGLDFSDLAKEIGDVD
>NC_019940.1|WP_015279349.1|357861_359259_-|cysteine--tRNA-ligase
MLQIYNSLTRQKAVFTPLVPGQVRMYVCGMTVYDYCHLGHARVMVVFDVVYRYLRHLGYEVTYIRNITDIDDKIIRRAGENDEPIAALTERFIAAMHEDAAALGVLPPSDEPRATAHIDEIQAMVATLLERGLAYRADNGDVYYAVGRFPGYGKLSGKDPQELRAGSRVEIGEAKRDPLDFVLWKAAKPGEPAWESPWGPGRPGWHIECSAMSTCALGAHFDIHGGGADLQFPHHENEIAQSEGATGEPFVEVWMHNGFVRVNDEKMSKSLGNFFTVREILARYRPEEVRYFILTSHYRSPLNYDEDHLQQARGALTRFYTALRGLPPAEPAGGEAFSERFHAAMDDDFATPEALAVLFELVREINRVRADDEARAAALGAELRRLGAVLGILQGDPEAYLRGEGLVVDAGPAALDDAAIDALIERRTAARQARQWAEADRLRDQLQEAGILLEDGPQGTTWRRG
>NC_019940.1|WP_015279350.1|359445_359934_+|peptidyl-prolyl-cis-trans-isomerase
MIKLTTNHGDILIELDPEKAPETCANFTQYVRDGHYDGTLFHRVINGFMIQGGGMDSSFSPLPTRQPIQNEAQNGLKNKTGTVAMARTNDPHSATSQFFINVSDNDFLDYPGQDGWGYCVFGKVTDGMDVVEKIKGVRTTSRRGHQDVPVEDVVIEKAVIVD
>NC_019940.1|WP_015279351.1|359956_360718_+|UDP-2,3-diacylglucosamine-diphosphatase
MARPDTGSGDPAGDGERLFISDLHLAPERPETVARFLDFLAGRARRAERLYILGDLFDAWIGDDDDTQPYPQIRTALRALTDSGTACRLLHGNRDFLIGRAFARDTGCTLLRDPTLIRLRGERVLLMHGDLLCTDDVAYQRFRRRVRNPLVRRLFLWRSLARRRAQAADYRRRSGSATAAKTAASMDVSQPTVARFMRRHVADRLIHGHTHRPADHAFTLDGHPVLRQVLAEWHPERGEVLVADAGGWRREPV
>NC_019940.1|WP_015279352.1|360731_361859_-|glycosyltransferase-family-2-protein
MPTPPSDALRCPPPVLSVVVPTFNEVDNVAELVARVAGALAGTDWELIFVDDDSPDGTADRARAIAATDRRVRVLQRIGRRGLSSACIEGMLASSAAYLAVMDGDLQHDAALLPQMLAALAEDDLDIVVGSRYVADGGLGDWAARRRSMSRLAGGLGRRLIKADLQDPMSGFFILRAEAFRTRVRRLSGVGFKLLLDLFASDGTPLRFREIPYRFGLRQAGASKLDNAVLWEYLLMLLQKLVGPVVPVRFIAFSLIGGLGVGVHLAVLWALFKGLGTSFLVGQAAATLVAMTSNFFLNNLLTYRDMRLRGRALLWGWASFVAACSIGALANVGIATYLFRAESFWLLSAFAGILVGAVWNYAVTAVYTWRRPRAA
>NC_019940.1|WP_015279353.1|361969_363568_+|glycosyltransferase-family-39-protein
MERPVPVPSPSLAAHWLILALAGITLWRLAVAWLLPVTQDEAYYFDWARALAWGYFDHPPGVAVLGLGTWLAPGSAPFSTLAARLGNLLAATATLLVLLAFYRRCGLRAPGDRLVALALAAASLPAIAGGILATPDTALALAWALALHEALAALQGDRRRWLTAGLAVGLGLLGKYTMVLIGPVLLWAILRADPRALRTPWPYLGGLVALLVFLPHVLWNADHGWVTMRFQFGHGFAVASGPLVEAPLPMPIGAPPAAEAASVVTSAPGSAGVAGYLGTQVALLGLLVLPLTASLLGRGGPRRIAATVSATLEPKARALLGAASVFPLAFFALVAWRSDVEPNWPVVYLLGAAPLAALAARPWWRWVLAAAAVNLLLATLYAVHGATGAPPLPAGQERILRETHGFRALAAAVAGLDGPIFADRYQTTAMLRFYAPGLPIGQWPGLTRPSEYLRGHLAVPGPAEIERAGGLWLISRGRAPALPGLTLTTTRTLWDCLGDTLLASPQSPCERPLHVWRLVHYRVGAGPPADRR
>NC_019940.1|WP_015279354.1|363801_369180_+|RecQ-family-ATP-dependent-DNA-helicase
MRRGRHRVRLGQASLTGSRHPQGADAARAATGAVSGHNRSVDTRLGDLLSRALVLDLEVGADGALHKIGALRGGAEFRRPGRFDERTALAELERFAGDAPFVLGHNLLGHDLPVLRARAPGLGLLARPVIDTLFLSPLAFPENPYHRLVKDYKLVSTSVSDPVADCRLAAQVFREQWAELDRRARSGREDDQDRLALYRFCFFGATDLELAPTGGQGIARVFAELGAPLLTVPEVLAVLDRLWTGRVCRTVARAQALRYLGEARLRPPLAYAIAWLQVAGARSVLPPWVRHQFPAVVELLHDLRDVPCGMPDCAWCGETHDPLAQLRRQFGLDAFRPVPSAPGGGSLQAAVVAHGMGDRSLLAILPTGGGKSLCFQLPALTRYLRRGQLTLVISPLQALMKDQVDNLARRTGTAAAAALYGSLTGPERGDVLERVRLGEVAILYVSPEQLRNRSLRRVLEAREIGAWVFDEAHCLSKWGHDFRPDYIYAARFIRELAEVQGVPVPPVACFTATAKPDVIAEILGHFNNELGLTLKRFEGGVERDNLSFEIRLARPQEKEAQLQGLLKEHLGGPGVRDGAGDAAAIVYAAKRKGTEELADCLARQGWAVAAFHAGLPAPEKRRIQDAFVAGQLQVICATNAFGMGVDKEDVRLVVHAEIPGSLENYLQEAGRAGRDQAPAACVLLYCEQDIEDQFRLAARSALTRADIAEILRGLRRARRDGEDCVVLTAGELLRDADLRIGFDAAENDADTRVRTAIAWLERAGLVERNENRTRVFDGRPAVPDLDTARRRIDGLDISAERRARWLAVLEALLECDPDEGLSTDDLAMLPVFRAAEGRPNERAAIWDRGATAGQRVLRTLHDMAEARLLQRGPQLSAFVRYKVRSPSAKILAQVCGVEQAMLEVLREEAPDADDGGWYPLSLRRLNQHLRDDKVDSNPELLRTLLASLARDGQGLAASRGSLELRQVERDHYRMRLHRDWAKLAETALRRQAVAEVVLATLIAKIPDGEPPNGERLVGFGTDELTAALAKRQGQVGHLTDPLAAVERGLLFLHEHGAISLQSGVAVFRQAMTIRIPPEAKGRYYTKGHFAPLAQHYAERIFQIHVMEAYARLGLERITRAIELVIAYFALDHRSFANKYFADRREMLERATTAESFRRIVDALDNPEQIAIVAAEPEANRLVLAGPGSGKTRVIVHRCAYLLRVRRVDPRSILILCYNRSAALELRRRLAALVDADARGVTIQTYHGFAMRLTGTSFAERAQQGQGGDDGFAGLIEAALDLLEGRADWPGIEADGLRERLLAGYRHILVDEYQDIDAQQYRLVAAIAGRTLAEDADAARLTLLAVGDDDQNIYAFRGASIEFIRRFEADYQARTHHLIENYRSSAHICAAAHALIAHNRERMKTGQRIGVDRRRRADPPGGRWSDLDPHGRGRVEVLEVADPGRQAAAFVERLRRLKSLGGSAWADFAVLAFRRRALQPIRAACEAAGVTVAWRDDLPPLSRVREIARFLDRLADLGHGEIAVAELRCWLPAAESPWRAILVDLIDDWREEAGDAPSAASRCLEFCYESLGELRNDRRLGDGVLFSTLHGAKGLEFPHVLIADDRLPARAQTDAEEWRRLYYVGMTRARETLALGCLPGGSGPRSEAIAGDWLLRTSVAIEPPPEEVLRRRYQLLTPADIDLGYAGRKAPDDPIHARLAAVVTGDRLKVVARDGALLLRDEQGAAIARLSRKATDEWRARLERIEAVRVVAMMRRRRDDGEGDFRTACRSPQWEYPLVELVWRSDDGDRSED
>NC_019940.1|WP_157633810.1|369359_369821_-|hypothetical-protein
MKSIGIDMEPATLERKTFLPGVRIEGTMLHVDESRLEYPGDILHEAGHIAVAPPSRRGRLKDQVSNDPAEEMMAIAWSWAALKHLQADPRIVFHDAFKGGSDNLIDAFSNGGGCGVPVLQWLGMTAEGPRAEELGVSPFPHMIEWVRTRETGG
>NC_019940.1|WP_015279356.1|371050_371533_-|hypothetical-protein
MKTIAYFAAAALLWLGAAASAAEYEYPPTPTSSPEAMLDHGDFQGTPWLSGGVGLDEREYILDHYADDFNLKLEFALAGGSYLGDVEVLITTGSGDIVMQALSEGPWFLTRLPAGTYHVQATSGDRTLKQTVQVPASGLRTVTFGAWHESGADAPMVPAY
>NC_019940.1|WP_015279357.1|371808_372105_-|DUF3096-domain-containing-protein
MEIPAFLAHWPLQAVLAVIAGLTILLFPRALNYAVAIYLLAVGALGLLHFVNGGAADARAVIALVAGALVLLKPNVLNYVIGVYLLLVGLLEAGVVRF

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Crispr_ID: NC_019940_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019940_2

355322-356334

TypeIII

Consensus_repeat	Method
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	PILER-CR
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	CRISPRCasFinder
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	CRT

14 spacers

RT,cas1,cas2,csx1,cas10,cmr3gr5

The CRISPR arrays of NC_019940_2

>merge|NC_019940|2|355322-356334|PILER-CR,CRISPRCasFinder,CRT
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGACACCGGACTCGTAGCCATTACCGAACCCGGTATAGGGCCTAGCACTTACCTGATGAAGAAGGTATTGAGACACCCCTAGCATCAGCAACACTGATCTGCGCCTGCGGCCTAGCACTTACCTGATGAAGAAGGTATTGAGACAACATGATCGCAACAATAAGCAATAACAATCTTGGCCTAGCACTTACCTGATGAAGAAGGTATTGAGACCTTAAGAAGCGGGCCCCTTTCTGAGTCCAGGCGTTGGCCTAGCACTTACCTGATGAAGAAGGTATTGAGACGTCACCGATCGCGCTTTTGCCACTCATGGTCGTCGGCCTAGCACTTACCTGATGAAGAAGGTATTGAGACCGAGAGAGAACAGTCGACTCCCCCCGATGATCGGCCTAGCACTTACCTGATGAAGAAGGTATTGAGACGGCCTGAAAAACGGCCCATAAACCCTATACAGAACGGCCTAGCACTTACCTGATGAAGAAGGTATTGAGACTGTGCGAACTCTCATGGGAATCATCCTTGATTTATGGCCTAGCACTTACCTGATGAAGAAGGTATTGAGACGATGTAGGCCAGCGGCGCTGACCATTGTCCAATAGGCCTAGCACTTACCTGATGAAGAAGGTATTGAGACCGATTTACATATAGGGATCTGTCGAGATGGATCAGGCCTAGCACTTACCTGATGAAGAAGGTATTGAGACGTCATCCAACTAGGCATGTGAGCCTCGATACGGGCCTAGCACTTACCTGATGAAGAAGGTATTGAGACGCAGATATTCATCCCCCCCGATAATGATTCCGAGGCCTAGCACTTACCTGATGAAGAAGGTATTGAGACGAATCGTGAGGATTCCTACCGACCTGCCACTAGCGGCCTAGCACTTACCTGATGAAGAAGGTATTGAGACCGCTCCTCGAAGGAGGGGTTATCTTTAGTTCCAGGCCTAGCACCTAGCTGATGAAGAGGCGAGCGTAGGG

>NC_019940|2|3|355322-356194|PILER-CR
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	ACCGGACTCGTAGCCATTACCGAACCCGGTATAG
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	ACCCCTAGCATCAGCAACACTGATCTGCGCCTGC
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	AACATGATCGCAACAATAAGCAATAACAATCTT
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	CTTAAGAAGCGGGCCCCTTTCTGAGTCCAGGCGTT
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GTCACCGATCGCGCTTTTGCCACTCATGGTCGTC
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	CGAGAGAGAACAGTCGACTCCCCCCGATGATC
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GGCCTGAAAAACGGCCCATAAACCCTATACAGAAC
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	TGTGCGAACTCTCATGGGAATCATCCTTGATTTAT
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GATGTAGGCCAGCGGCGCTGACCATTGTCCAATA
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	CGATTTACATATAGGGATCTGTCGAGATGGATCA
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GTCATCCAACTAGGCATGTGAGCCTCGATACG
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GCAGATATTCATCCCCCCCGATAATGATTCCGA
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC

>NC_019940|2|2|355322-356334|CRISPRCasFinder
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	ACCGGACTCGTAGCCATTACCGAACCCGGTATAG
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	ACCCCTAGCATCAGCAACACTGATCTGCGCCTGC
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	AACATGATCGCAACAATAAGCAATAACAATCTT
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	CTTAAGAAGCGGGCCCCTTTCTGAGTCCAGGCGTT
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GTCACCGATCGCGCTTTTGCCACTCATGGTCGTC
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	CGAGAGAGAACAGTCGACTCCCCCCGATGATC
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GGCCTGAAAAACGGCCCATAAACCCTATACAGAAC
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	TGTGCGAACTCTCATGGGAATCATCCTTGATTTAT
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GATGTAGGCCAGCGGCGCTGACCATTGTCCAATA
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	CGATTTACATATAGGGATCTGTCGAGATGGATCA
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GTCATCCAACTAGGCATGTGAGCCTCGATACG
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GCAGATATTCATCCCCCCCGATAATGATTCCGA
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GAATCGTGAGGATTCCTACCGACCTGCCACTAGC
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	CGCTCCTCGAAGGAGGGGTTATCTTTAGTTCCA
GGCCTAGCACCTAGCTGATGAAGAGGCGAGCGTAGGG

>NC_019940|2|2|355322-356333|CRT
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	ACCGGACTCGTAGCCATTACCGAACCCGGTATAG
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	ACCCCTAGCATCAGCAACACTGATCTGCGCCTGC
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	AACATGATCGCAACAATAAGCAATAACAATCTT
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	CTTAAGAAGCGGGCCCCTTTCTGAGTCCAGGCGTT
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GTCACCGATCGCGCTTTTGCCACTCATGGTCGTC
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	CGAGAGAGAACAGTCGACTCCCCCCGATGATC
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GGCCTGAAAAACGGCCCATAAACCCTATACAGAAC
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	TGTGCGAACTCTCATGGGAATCATCCTTGATTTAT
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GATGTAGGCCAGCGGCGCTGACCATTGTCCAATA
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	CGATTTACATATAGGGATCTGTCGAGATGGATCA
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GTCATCCAACTAGGCATGTGAGCCTCGATACG
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GCAGATATTCATCCCCCCCGATAATGATTCCGA
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	GAATCGTGAGGATTCCTACCGACCTGCCACTAGC
GGCCTAGCACTTACCTGATGAAGAAGGTATTGAGAC	CGCTCCTCGAAGGAGGGGTTATCTTTAGTTCCA
GGCCTAGCACCTAGCTGATGAAGAGGCGAGCGTAGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019940.1\|WP_015279356.1\|371050_371533_-\|hypothetical-protein	unknown	unknown	unknown
NC_019940.1\|WP_015279342.1\|350751_351873_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224486
NC_019940.1\|WP_015279341.1\|348443_349247_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|312526
NC_019940.1\|WP_015279337.1\|342526_343930_-\|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl\|CDD\|370625
NC_019940.1\|WP_157633809.1\|354400_355213_+\|Retron-type-reverse-transcriptase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_019940.1\|WP_015279344.1\|352693_352978_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_019940.1\|WP_015279351.1\|359956_360718_+\|UDP-2,3-diacylglucosamine-diphosphatase	unknown	unknown	gnl\|CDD\|235420
NC_019940.1\|WP_015279352.1\|360731_361859_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133062
NC_019940.1\|WP_015279345.1\|353040_353382_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NC_019940.1\|WP_015279343.1\|352078_352636_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234714
NC_019940.1\|WP_015279346.1\|353378_354377_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_019940.1\|WP_157633810.1\|369359_369821_-\|hypothetical-protein	unknown	unknown	unknown
NC_019940.1\|WP_015279349.1\|357861_359259_-\|cysteine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234705
NC_019940.1\|WP_015279350.1\|359445_359934_+\|peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|238901
NC_019940.1\|WP_015279348.1\|357189_357750_-\|transposase	unknown	unknown	gnl\|CDD\|224854
NC_019940.1\|WP_015279357.1\|371808_372105_-\|DUF3096-domain-containing-protein	unknown	unknown	gnl\|CDD\|371454
NC_019940.1\|WP_015279354.1\|363801_369180_+\|RecQ-family-ATP-dependent-DNA-helicase	unknown	unknown	gnl\|CDD\|223588
NC_019940.1\|WP_015279353.1\|361969_363568_+\|glycosyltransferase-family-39-protein	unknown	unknown	gnl\|CDD\|379080
NC_019940.1\|WP_172637449.1\|343926_346173_-\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl\|CDD\|187810
NC_019940.1\|WP_015279340.1\|347490_347808_-\|CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	gnl\|CDD\|274214

Protein	Function_ID	Function_description	E-value
NC_019940.1\|WP_015279342.1\|350751_351873_+\|hypothetical-protein	gnl\|CDD\|224486	COG1570, XseA, Exonuclease VII, large subunit [DNA replication, recombination, and repair].	0.00139372
NC_019940.1\|WP_015279341.1\|348443_349247_+\|hypothetical-protein	gnl\|CDD\|312526	pfam09002, DUF1887, Domain of unknown function (DUF1887). This domain is found in a set of hypothetical bacterial proteins.	0.00848567
NC_019940.1\|WP_015279337.1\|342526_343930_-\|CRISPR-associated-protein-Cmr3	gnl\|CDD\|370625	pfam09700, Cas_Cmr3, CRISPR-associated protein (Cas_Cmr3). CRISPR is a term for Clustered Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This highly divergent family, found in at least ten different archaeal and bacterial species, is represented by TM1793 from Thermotoga maritima.	7.48223e-31
NC_019940.1\|WP_157633809.1\|354400_355213_+\|Retron-type-reverse-transcriptase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	1.45329e-75
NC_019940.1\|WP_015279344.1\|352693_352978_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.67245e-12
NC_019940.1\|WP_015279351.1\|359956_360718_+\|UDP-2,3-diacylglucosamine-diphosphatase	gnl\|CDD\|235420	PRK05340, PRK05340, UDP-2,3-diacylglucosamine hydrolase; Provisional.	2.68191e-113
NC_019940.1\|WP_015279352.1\|360731_361859_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|133062	cd06442, DPM1_like, DPM1_like represents putative enzymes similar to eukaryotic DPM1. Proteins similar to eukaryotic DPM1, including enzymes from bacteria and archaea; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. This protein family belongs to Glycosyltransferase 2 superfamily.	3.09395e-84
NC_019940.1\|WP_015279345.1\|353040_353382_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.4403e-13
NC_019940.1\|WP_015279343.1\|352078_352636_+\|hypothetical-protein	gnl\|CDD\|234714	PRK00286, xseA, exodeoxyribonuclease VII large subunit; Reviewed.	0.00337628
NC_019940.1\|WP_015279346.1\|353378_354377_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	9.1117e-72
NC_019940.1\|WP_015279349.1\|357861_359259_-\|cysteine--tRNA-ligase	gnl\|CDD\|234705	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated.	0
NC_019940.1\|WP_015279350.1\|359445_359934_+\|peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|238901	cd01920, cyclophilin_EcCYP_like, cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these have reduced affinity for cyclosporin A. E. coli cyclophilin A has a similar peptidylprolyl cis- trans isomerase activity to the human cyclophilin A. Most members of this subfamily contain a phenylalanine residue at the position equivalent to Human cyclophilin W121, where a tyrptophan has been shown to be important for cyclophilin binding.	5.43754e-81
NC_019940.1\|WP_015279348.1\|357189_357750_-\|transposase	gnl\|CDD\|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.38803e-29
NC_019940.1\|WP_015279357.1\|371808_372105_-\|DUF3096-domain-containing-protein	gnl\|CDD\|371454	pfam11295, DUF3096, Protein of unknown function (DUF3096). This family of proteins with unknown function appears to be restricted to Proteobacteria.	0.000629287
NC_019940.1\|WP_015279354.1\|363801_369180_+\|RecQ-family-ATP-dependent-DNA-helicase	gnl\|CDD\|223588	COG0514, RecQ, Superfamily II DNA helicase [DNA replication, recombination, and repair].	2.60388e-100
NC_019940.1\|WP_015279353.1\|361969_363568_+\|glycosyltransferase-family-39-protein	gnl\|CDD\|379080	pfam13231, PMT_2, Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.	1.16132e-18
NC_019940.1\|WP_172637449.1\|343926_346173_-\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.71799e-43
NC_019940.1\|WP_015279340.1\|347490_347808_-\|CRISPR-associated-protein	gnl\|CDD\|274214	TIGR02584, hypothetical_protein_NE0113, CRISPR-associated protein, NE0113 family. Members of this minor CRISPR-associated (Cas) protein family are found in cas gene clusters in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, Mannheimia succiniciproducens MBEL55E, and Verrucomicrobium spinosum.	1.4723e-14

>NC_019940.1|WP_157633809.1|354400_355213_+|Retron-type-reverse-transcriptase
MSPEVLDRAWRKLKGEHTPWSPTVSRDDLQHHLMRHLLACREEVLDGAYRPLPLRQFPVRKPDGRQRVLTAQFLRDKLVQRALLTVLEPRAEALFHDDSFAYRPERNVAKALAKVRERVRIGLDWLVDADIEKFFDSIPHRPLLRVLDGFVADAKAMKLIERWLGQGAHVRSLLATPRGIAQGAILSPLFCNLYLHGFDRSLDSAHIPFVRFADDFLLFAPTRSDAGRAMEHAARRLERLDLRLHPDKTRVVRSGREVIFLGETLPGPTR
>NC_019940.1|WP_015279346.1|353378_354377_+|CRISPR-associated-endonuclease-Cas1
MILVVDRRDSVLRHDSGVLCLEREGGETRRAPINQLELVVVYGNPLAETAVWRKLAAAGVPTVLLPVRGRDGAAVLGNGLATQLPLRRLQHRRAAEPARALELARWILAQKLASYDLPLQPLRRRHGADEAACAGLLRQRDRTLAALATARSRDELMGLEGQLAHAWFALLAKRLAPAWGFTGRNRRPPQDPINALFSLGYTLLGAEVHQGVVAAGLDPSLGFLHQPVPGREAMVLDLTEPFRSAVDHFVLDWIAVDGPRQADYYYREADGCRLSKTARPGFFQAWASYRHHWPYAVRLDPSADWPASTLREQIRGQIERLRSAMKTPEAPS
>NC_019940.1|WP_015279345.1|353040_353382_+|CRISPR-associated-endonuclease-Cas2
MKHWSLIAYDIRDPRRLRRVHLCLRRQALAVQKSVFLIEADERRLAEILAELRRRADNREDDIRLYAIPDPAAIWAAGRQSERVANLYGGAPAEAERPRRGRWLKGLFGREAA
>NC_019940.1|WP_015279344.1|352693_352978_+|CRISPR-associated-endonuclease-Cas2
MARKPAVIAYDIRCDKRRRRAARCLKGWRLDGQYSLIECRLTEAEAQELFLQLVDIIDRDEDALLLAWMDGTRESCPVTRCARIGFRKPALYLD
>NC_019940.1|WP_015279343.1|352078_352636_+|hypothetical-protein
MSPDNHALTVDLDDLPAEATRRGDDNEQRVDQALRRHTESLLPAMLERGRHRLVREHLDTELALGFEHRRQALSMALESRLQSIREACNHLLVTGKAHLRRQRIEYFGEVYRQLEQRMSQLADDYLAEADTRFARIEGLKSEHLRQREQQRLERSADDFLATLDRLMDDFRAIISENVDHRRSSL
>NC_019940.1|WP_015279342.1|350751_351873_+|hypothetical-protein
MRLTSFFRLGWTVQLFVGVALFSVSFLIELDVMQRLFGTSPAAIVLVGGFELGKAAAIVWHRYLALASSAVYPVQTRVVSAGFRSGLVLLSLLCSLLYLGAQLDRPNLVAVRAAEVARIDARLAEDLRRLETAREARFQTDEARRRTEYEDARAEHQRRIVELEDRLREEMEDRLREEMDNVVGGTFKGPRYLELSERLELTRGERDAALTRLSQRHLREATQLAETLARELAAQRERLTAAAEARRQAVRTATFDDDERVDNPLVTAFLRTTDALSGHQLTPPQFVFGLALFLSALIELGIVLAFDTVTLVAIPALEAQHREDVTTEALMAEVSGNATREGIRHRETMERIRKGAERAMDEAEAHIGPRQAA
>NC_019940.1|WP_015279341.1|348443_349247_+|hypothetical-protein
MTCSPVDLRTGLLVGIGLVTNSLFEWLADIGTWFGGGTVDDWLPVHRLLAVGLFAGELLAVAAYARGARKRYRPRVGVEPQPAQVHGLILFLSNLSAEQARAVQAGLTTLDGLAAFRAAHGGLNWRMPLEAIAHHAPRLQHVIVICSAGRTGSAGQWPLFRALVQRVFPGAAFELRSAAQLDSRFGAGIDFEDVDGVAQATDDAYVHLLERGLPHSEILIDVTGGQKTNAIAATAVALAEGRRIQYVACDRDTCTCHLNVYDVTYDG
>NC_019940.1|WP_015279340.1|347490_347808_-|CRISPR-associated-protein
MTTPSAGARQSHEYPHRVLLMVTGRTPQVVTETLYALACRPGPGERRFVPTEIHLITTAEGAQDARIALLDPKDGWFQRLCAASSVVRPRFRTRFRGATHASITV
>NC_019940.1|WP_172637449.1|343926_346173_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MAAARPPDGEARAYVGRRRGSITGKGDDSKRRGCAATDREISGCGGARGRRGGCLVQMAREQQGVGAAMTSGTENATAGATDKAFIVAIALGPVGRFIAGGRRSRDLWYGSRLLSELTRQAANSLHENGSTTLYVPLPETLYCDYWSKPHQGPVIPNKILALVKAKDAEQVRDDLDRARKAVLDFLAEEVRKLAEDEKWKIGVDRSALQAQADAIEGGDFVEFYAAWAPLSGDEPAAVERARDVLLAGRKAARVFPAPSWTKPGRPKCSLDPGRDSVMVEENPRAKPRESTRLMMDREQRGIRRDERLDAIGLLRRRAVFEEVVETNRADDGKLCLPKLPFPPLARVAADPWLEGAAANSRHLLEAIVDELKRLDEGRGDRNPLLLISSPCREPAKALDENGPFPYDPSLLFENGIQTMRRELDRRRKSLGNDDPSDGEYLEPCKKAASALREMERPVRQLHDLFGFPSPYYAMLEADGDDMGHLLGELTGERRTRAVEALGEFARHAWDEIDGCHGFAFYVGGDELTAYLPVDKALELVGALSGLFTAEMRASKVWKHDSCPTLSAGVVIAHQKEDMRAVRDRASAALKRAKRHRKHERDRSSTDPSVQGESGWVCIEERPAGGTARTLVGPIDRIRNEQAEWGQLIARAGNDRDLSLATAHGLLEWADRFRTNEAGSGDLGIALAQASVWQRLKRRDQDRGELRWLQRFLAARSWAEIRDYANAILLADRIADIAAQRQPLGRRTR
>NC_019940.1|WP_015279337.1|342526_343930_-|CRISPR-associated-protein-Cmr3
MTRETWYLTPRDPLVLGDGRGPVPFVERKTHPLPLPGTLAGMVRASFVQDRSEVSSAEALALLDIRVGAPWLVRLADPVRGLDGGVEHHYVFAPADARVAATGRLERAAVIALNGGQDGEGVYWPPGFPRLDHLVLLPERSDDGSKYEVPRRLFWPLGALVNWSLGEDPRSDAFECVAEPPRPADGSSPDGDDPHVPTRPEQRTHVGIDDEAQTADPSILFSSAGQRMAPHFSIAVEVDLPPQCPPGPAAHALGVLGGESRLTSIVRRPAAQSGFGFPPFSDWEGRYRHALEAAKDPLGGIRLQLLSHAFLPPQDGDEGWACLPSWLESRRHPRLPEGLYLRLVALCVPGPLAISGWDLQAVAAGTPDNGGRRTHSGGAPREVRRLVPAGSLYYFALEDAQGAPVTEREKWLDACRCLWWELLDPEGPGERTDETRHRAAAGADGHGRILPGLWSPGAAMASGASVR
>NC_019940.1|WP_015279348.1|357189_357750_-|transposase
MADWRRVFEPGGTYCFTLVTERRAPIFADERSRAILRRALEATKARWPFEIVAIVLMPDHLHTLWCLPANDSAYPTRIGWIKKEFTKGWLASGGAEQALSASRLRQRRRGVLQRRFWEHAFRSERDLHRHLDYLHYNPVKHGYVGCPRDWPWSSFHRYCRAGVYTEDWGCTGLDFSDLAKEIGDVD
>NC_019940.1|WP_015279349.1|357861_359259_-|cysteine--tRNA-ligase
MLQIYNSLTRQKAVFTPLVPGQVRMYVCGMTVYDYCHLGHARVMVVFDVVYRYLRHLGYEVTYIRNITDIDDKIIRRAGENDEPIAALTERFIAAMHEDAAALGVLPPSDEPRATAHIDEIQAMVATLLERGLAYRADNGDVYYAVGRFPGYGKLSGKDPQELRAGSRVEIGEAKRDPLDFVLWKAAKPGEPAWESPWGPGRPGWHIECSAMSTCALGAHFDIHGGGADLQFPHHENEIAQSEGATGEPFVEVWMHNGFVRVNDEKMSKSLGNFFTVREILARYRPEEVRYFILTSHYRSPLNYDEDHLQQARGALTRFYTALRGLPPAEPAGGEAFSERFHAAMDDDFATPEALAVLFELVREINRVRADDEARAAALGAELRRLGAVLGILQGDPEAYLRGEGLVVDAGPAALDDAAIDALIERRTAARQARQWAEADRLRDQLQEAGILLEDGPQGTTWRRG
>NC_019940.1|WP_015279350.1|359445_359934_+|peptidyl-prolyl-cis-trans-isomerase
MIKLTTNHGDILIELDPEKAPETCANFTQYVRDGHYDGTLFHRVINGFMIQGGGMDSSFSPLPTRQPIQNEAQNGLKNKTGTVAMARTNDPHSATSQFFINVSDNDFLDYPGQDGWGYCVFGKVTDGMDVVEKIKGVRTTSRRGHQDVPVEDVVIEKAVIVD
>NC_019940.1|WP_015279351.1|359956_360718_+|UDP-2,3-diacylglucosamine-diphosphatase
MARPDTGSGDPAGDGERLFISDLHLAPERPETVARFLDFLAGRARRAERLYILGDLFDAWIGDDDDTQPYPQIRTALRALTDSGTACRLLHGNRDFLIGRAFARDTGCTLLRDPTLIRLRGERVLLMHGDLLCTDDVAYQRFRRRVRNPLVRRLFLWRSLARRRAQAADYRRRSGSATAAKTAASMDVSQPTVARFMRRHVADRLIHGHTHRPADHAFTLDGHPVLRQVLAEWHPERGEVLVADAGGWRREPV
>NC_019940.1|WP_015279352.1|360731_361859_-|glycosyltransferase-family-2-protein
MPTPPSDALRCPPPVLSVVVPTFNEVDNVAELVARVAGALAGTDWELIFVDDDSPDGTADRARAIAATDRRVRVLQRIGRRGLSSACIEGMLASSAAYLAVMDGDLQHDAALLPQMLAALAEDDLDIVVGSRYVADGGLGDWAARRRSMSRLAGGLGRRLIKADLQDPMSGFFILRAEAFRTRVRRLSGVGFKLLLDLFASDGTPLRFREIPYRFGLRQAGASKLDNAVLWEYLLMLLQKLVGPVVPVRFIAFSLIGGLGVGVHLAVLWALFKGLGTSFLVGQAAATLVAMTSNFFLNNLLTYRDMRLRGRALLWGWASFVAACSIGALANVGIATYLFRAESFWLLSAFAGILVGAVWNYAVTAVYTWRRPRAA
>NC_019940.1|WP_015279353.1|361969_363568_+|glycosyltransferase-family-39-protein
MERPVPVPSPSLAAHWLILALAGITLWRLAVAWLLPVTQDEAYYFDWARALAWGYFDHPPGVAVLGLGTWLAPGSAPFSTLAARLGNLLAATATLLVLLAFYRRCGLRAPGDRLVALALAAASLPAIAGGILATPDTALALAWALALHEALAALQGDRRRWLTAGLAVGLGLLGKYTMVLIGPVLLWAILRADPRALRTPWPYLGGLVALLVFLPHVLWNADHGWVTMRFQFGHGFAVASGPLVEAPLPMPIGAPPAAEAASVVTSAPGSAGVAGYLGTQVALLGLLVLPLTASLLGRGGPRRIAATVSATLEPKARALLGAASVFPLAFFALVAWRSDVEPNWPVVYLLGAAPLAALAARPWWRWVLAAAAVNLLLATLYAVHGATGAPPLPAGQERILRETHGFRALAAAVAGLDGPIFADRYQTTAMLRFYAPGLPIGQWPGLTRPSEYLRGHLAVPGPAEIERAGGLWLISRGRAPALPGLTLTTTRTLWDCLGDTLLASPQSPCERPLHVWRLVHYRVGAGPPADRR
>NC_019940.1|WP_015279354.1|363801_369180_+|RecQ-family-ATP-dependent-DNA-helicase
MRRGRHRVRLGQASLTGSRHPQGADAARAATGAVSGHNRSVDTRLGDLLSRALVLDLEVGADGALHKIGALRGGAEFRRPGRFDERTALAELERFAGDAPFVLGHNLLGHDLPVLRARAPGLGLLARPVIDTLFLSPLAFPENPYHRLVKDYKLVSTSVSDPVADCRLAAQVFREQWAELDRRARSGREDDQDRLALYRFCFFGATDLELAPTGGQGIARVFAELGAPLLTVPEVLAVLDRLWTGRVCRTVARAQALRYLGEARLRPPLAYAIAWLQVAGARSVLPPWVRHQFPAVVELLHDLRDVPCGMPDCAWCGETHDPLAQLRRQFGLDAFRPVPSAPGGGSLQAAVVAHGMGDRSLLAILPTGGGKSLCFQLPALTRYLRRGQLTLVISPLQALMKDQVDNLARRTGTAAAAALYGSLTGPERGDVLERVRLGEVAILYVSPEQLRNRSLRRVLEAREIGAWVFDEAHCLSKWGHDFRPDYIYAARFIRELAEVQGVPVPPVACFTATAKPDVIAEILGHFNNELGLTLKRFEGGVERDNLSFEIRLARPQEKEAQLQGLLKEHLGGPGVRDGAGDAAAIVYAAKRKGTEELADCLARQGWAVAAFHAGLPAPEKRRIQDAFVAGQLQVICATNAFGMGVDKEDVRLVVHAEIPGSLENYLQEAGRAGRDQAPAACVLLYCEQDIEDQFRLAARSALTRADIAEILRGLRRARRDGEDCVVLTAGELLRDADLRIGFDAAENDADTRVRTAIAWLERAGLVERNENRTRVFDGRPAVPDLDTARRRIDGLDISAERRARWLAVLEALLECDPDEGLSTDDLAMLPVFRAAEGRPNERAAIWDRGATAGQRVLRTLHDMAEARLLQRGPQLSAFVRYKVRSPSAKILAQVCGVEQAMLEVLREEAPDADDGGWYPLSLRRLNQHLRDDKVDSNPELLRTLLASLARDGQGLAASRGSLELRQVERDHYRMRLHRDWAKLAETALRRQAVAEVVLATLIAKIPDGEPPNGERLVGFGTDELTAALAKRQGQVGHLTDPLAAVERGLLFLHEHGAISLQSGVAVFRQAMTIRIPPEAKGRYYTKGHFAPLAQHYAERIFQIHVMEAYARLGLERITRAIELVIAYFALDHRSFANKYFADRREMLERATTAESFRRIVDALDNPEQIAIVAAEPEANRLVLAGPGSGKTRVIVHRCAYLLRVRRVDPRSILILCYNRSAALELRRRLAALVDADARGVTIQTYHGFAMRLTGTSFAERAQQGQGGDDGFAGLIEAALDLLEGRADWPGIEADGLRERLLAGYRHILVDEYQDIDAQQYRLVAAIAGRTLAEDADAARLTLLAVGDDDQNIYAFRGASIEFIRRFEADYQARTHHLIENYRSSAHICAAAHALIAHNRERMKTGQRIGVDRRRRADPPGGRWSDLDPHGRGRVEVLEVADPGRQAAAFVERLRRLKSLGGSAWADFAVLAFRRRALQPIRAACEAAGVTVAWRDDLPPLSRVREIARFLDRLADLGHGEIAVAELRCWLPAAESPWRAILVDLIDDWREEAGDAPSAASRCLEFCYESLGELRNDRRLGDGVLFSTLHGAKGLEFPHVLIADDRLPARAQTDAEEWRRLYYVGMTRARETLALGCLPGGSGPRSEAIAGDWLLRTSVAIEPPPEEVLRRRYQLLTPADIDLGYAGRKAPDDPIHARLAAVVTGDRLKVVARDGALLLRDEQGAAIARLSRKATDEWRARLERIEAVRVVAMMRRRRDDGEGDFRTACRSPQWEYPLVELVWRSDDGDRSED
>NC_019940.1|WP_157633810.1|369359_369821_-|hypothetical-protein
MKSIGIDMEPATLERKTFLPGVRIEGTMLHVDESRLEYPGDILHEAGHIAVAPPSRRGRLKDQVSNDPAEEMMAIAWSWAALKHLQADPRIVFHDAFKGGSDNLIDAFSNGGGCGVPVLQWLGMTAEGPRAEELGVSPFPHMIEWVRTRETGG
>NC_019940.1|WP_015279356.1|371050_371533_-|hypothetical-protein
MKTIAYFAAAALLWLGAAASAAEYEYPPTPTSSPEAMLDHGDFQGTPWLSGGVGLDEREYILDHYADDFNLKLEFALAGGSYLGDVEVLITTGSGDIVMQALSEGPWFLTRLPAGTYHVQATSGDRTLKQTVQVPASGLRTVTFGAWHESGADAPMVPAY
>NC_019940.1|WP_015279357.1|371808_372105_-|DUF3096-domain-containing-protein
MEIPAFLAHWPLQAVLAVIAGLTILLFPRALNYAVAIYLLAVGALGLLHFVNGGAADARAVIALVAGALVLLKPNVLNYVIGVYLLLVGLLEAGVVRF

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Crispr_ID: NC_019940_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019940_4

1382797-1387045

Unclear

Consensus_repeat	Method
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CRISPRCasFinder
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CRT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	PILER-CR

58 spacers

cas2,cas1,cas8u1,cas3,csb2gr5,csb1gr7,WYL

The CRISPR arrays of NC_019940_4

>merge|NC_019940|4|1382797-1387045|CRISPRCasFinder,CRT,PILER-CR
CACGTAATAGGGCCGCGGCTATTCGCCGCGGAATTCCCTTGGTCTCCGACCTGTGCGGACAATGTCTCGCCCGCTTCAATGAGGCTACGGCTATTCGTCGCGGAATTCGTCCACGCGAACTCCTCCGGCCAATGCAGGGTGGCCGGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCCGGTCTTCCGCAAGCACTGCGCGCCCTTCTGGCGACCGTGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGTAGTCGATCGTGCCTTGCCCCTTGTAGCTCCTCCACAGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCCAACACCGACTGCACCCTCGCCACGTCGGCCGGATCGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCCGTTCTTCCCGGAGACGTGGACCGTAGCCCTCGGCGAGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCTCACCCGCGAGCACGGCGGCACCACGCTGGCGCTACCGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGGTCGCGACGGTCGGTGTGAAGATGGGGACGACGAGGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCTGTCAGACGGTCGGTTGCGCGGCCTGACGTATGTTGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGCACTGGCGCCGGCTAATCACCGCACAACCCCGCCAGCGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCACCGAAATGATAGGCGCCCATAACATGGCACCGGATGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCAACAACAACCGCAACGGACGATGGAGTTTCTCGCGGAGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCCCTGCCCCTGCCCCGCGTCGCGCCTATCGAGCATCTGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCACAGTAAATGGCGAGTACGAAGAGGTGGCAACAGACGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCCCGTTGCCGCAACCGCCGGCGCCACGACGGCCCGCCGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGTCGTCGGCGTGGATGGCACCGGTCGCGTAGGACCAGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCAGCGCTGCCGGCAATCCACACGGGCGCCGTGCCGAAGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGTGTAGAGAGGCAGCACTGGATTATGTTCTGGCTCCATGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGCTGGGCCGCGACCAAACCACAGAGTGGCCCCGGACGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCCAGAGCGTCCGTGAGCGGCTCGCTGAGGTCCGCAAGGGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCAATCAGGGATAAAAACGCTTCCGGCAACGGCTCAGGCGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGTCGCCGCCGTTGTCCCACTGGGTGTGCGCGGCATCGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCCCCGCTACGCCACCATCCGCGCCGCCTGGCGCGCCGTGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGCGGGGGAGAAGCACGGGCACAAATCGGATTACACGGGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGCCGAGAAGACGGCGGAGCTCAATGCCGAGCAGTCGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGCGTAGGATGGAGCGACAACTCTGGTGGTTGGGATTGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCATGCCAACGCCGTCGGCACCGGCATGAAGGTCTCTTACGAGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGTCGCCGACAAGGCTCAGCCGGGCAGCGCTCAATACGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCCGCTGAACTCGACCACGGTGCGGTCGAAGCTGTAAGGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCTCCGCGGCCAATCGCCTGTTCAAGGAGGCCCTGCCGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCTTCCGCCCCTTGGTGCTCCAGCCGCGGGCTGGAGAAGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGTGTGGCAGGAGTTTGTTGATTTCCACGAGATTCGAATGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCCGGCGCCCACGGCTCGCCCCAGGGGCTGGTTTCGTTCTGGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCTGCGCGAATAGCGGCTTGAATTGATTTGGTACATTTTGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCAAAGCGAGGAACCTTGGCTATCGATTTCTCGCCGCTGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCAACATGTGCAGATTGAGCTGCTTGTCGCGGATCTGGGCGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCCTTGTCGGGCAAATACCCAACCGTTTTTATTACTCCGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCAGTGAAGGCACAATGCGATAAGGATAAGCTCCGCAAGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCCGCCTGACCGATCTTGCGCCGAGGCATGACCGCCGAAGGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCACGATTCAAGCGCGCAATCCGAGCCAGCGGCGGTTGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCCTTACCGTGGGCTCTATTAATTTGGTCGAATCGTAAGGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGGTTGGATTGGTGATGGCGTCGCCATTGCCAAGTACGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCTTCATCGGGGTACACCCAATTACCGCCGAACCGGTACGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCCGGACGTGGCCATGGAATCCAGCCAGAATCCAGCCAGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCAACGAGCGATCGTCCCGCGCGGAGAGCCGTCGCGCTGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGCGTCCACACGGCCCGGCTCACCTGGAGTGAGCCGGAGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGTCGGAGTGATCAGATCCCCGGTAAAGCTGCCCTGGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGTTGTTCGCCATCCTCAAGCGCCAGCGCGAGCTTAGGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCTCCCTCGTATCCGGCTGCCACTTGCACCTCCTCGTATTGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCTAAATTGTCTATTTTTTCAATATTCGTTTCATCTAGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCCCACCACATGATCTGCGCCTGCGCCTCGTCGCCCCGGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCTCCAGTCGGACGGCCAGCGGTCCCACGAGCAAGGTCACGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCCCTGCCTTTCGCTAATGAGGGGCTGTCCGTACCGGAGGCGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCAAGGTGCTGAGGTGGTTCCTCTTCCAATAGTCGTGGGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCTCTGTTTCCGAAGCAATTAGGGAAATGGATGAGGTTTGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCCGCAGCGTGAGATAAGCCAAATGCCGATCCTCGAAGAGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCATGTACGTCTCATAATGATGTCGCAAACGCGCTTATGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTCGGTCACGACCGCGCGGGCGTTGGCGATGCCGCTGTAGCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC

>NC_019940|4|4|1382797-1387045|CRISPRCasFinder
CACGTAATAGGGCCGCGGCTATTCGCCGCGGAATTC	CCTTGGTCTCCGACCTGTGCGGACAATGTCTCGCCC
GCTTCAATGAGGCTACGGCTATTCGTCGCGGAATTC	GTCCACGCGAACTCCTCCGGCCAATGCAGGGTGGCCG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGGTCTTCCGCAAGCACTGCGCGCCCTTCTGGCGACCGT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTAGTCGATCGTGCCTTGCCCCTTGTAGCTCCTCCACA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CAACACCGACTGCACCCTCGCCACGTCGGCCGGATC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGTTCTTCCCGGAGACGTGGACCGTAGCCCTCGGCGA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TCACCCGCGAGCACGGCGGCACCACGCTGGCGCTACC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GGTCGCGACGGTCGGTGTGAAGATGGGGACGACGAG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TGTCAGACGGTCGGTTGCGCGGCCTGACGTATGTT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCACTGGCGCCGGCTAATCACCGCACAACCCCGCCAGC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	ACCGAAATGATAGGCGCCCATAACATGGCACCGGAT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AACAACAACCGCAACGGACGATGGAGTTTCTCGCGGA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CCTGCCCCTGCCCCGCGTCGCGCCTATCGAGCATCT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	ACAGTAAATGGCGAGTACGAAGAGGTGGCAACAGAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CCGTTGCCGCAACCGCCGGCGCCACGACGGCCCGCC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTCGTCGGCGTGGATGGCACCGGTCGCGTAGGACCA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AGCGCTGCCGGCAATCCACACGGGCGCCGTGCCGAA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTGTAGAGAGGCAGCACTGGATTATGTTCTGGCTCCAT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCTGGGCCGCGACCAAACCACAGAGTGGCCCCGGAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CAGAGCGTCCGTGAGCGGCTCGCTGAGGTCCGCAAGG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AATCAGGGATAAAAACGCTTCCGGCAACGGCTCAGGC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTCGCCGCCGTTGTCCCACTGGGTGTGCGCGGCATC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CCCGCTACGCCACCATCCGCGCCGCCTGGCGCGCCGT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCGGGGGAGAAGCACGGGCACAAATCGGATTACACGG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCCGAGAAGACGGCGGAGCTCAATGCCGAGCAGTC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCGTAGGATGGAGCGACAACTCTGGTGGTTGGGATT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	ATGCCAACGCCGTCGGCACCGGCATGAAGGTCTCTTACGA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTCGCCGACAAGGCTCAGCCGGGCAGCGCTCAATAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGCTGAACTCGACCACGGTGCGGTCGAAGCTGTAAG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TCCGCGGCCAATCGCCTGTTCAAGGAGGCCCTGCC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TTCCGCCCCTTGGTGCTCCAGCCGCGGGCTGGAGAA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTGTGGCAGGAGTTTGTTGATTTCCACGAGATTCGAAT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGGCGCCCACGGCTCGCCCCAGGGGCTGGTTTCGTTCTG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TGCGCGAATAGCGGCTTGAATTGATTTGGTACATTTT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AAAGCGAGGAACCTTGGCTATCGATTTCTCGCCGCT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AACATGTGCAGATTGAGCTGCTTGTCGCGGATCTGGGC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CTTGTCGGGCAAATACCCAACCGTTTTTATTACTCC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AGTGAAGGCACAATGCGATAAGGATAAGCTCCGCAA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGCCTGACCGATCTTGCGCCGAGGCATGACCGCCGAAG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	ACGATTCAAGCGCGCAATCCGAGCCAGCGGCGGTT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CTTACCGTGGGCTCTATTAATTTGGTCGAATCGTAAG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GGTTGGATTGGTGATGGCGTCGCCATTGCCAAGTAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TTCATCGGGGTACACCCAATTACCGCCGAACCGGTAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGGACGTGGCCATGGAATCCAGCCAGAATCCAGCCA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AACGAGCGATCGTCCCGCGCGGAGAGCCGTCGCGCT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCGTCCACACGGCCCGGCTCACCTGGAGTGAGCCGGA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTCGGAGTGATCAGATCCCCGGTAAAGCTGCCCTG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTTGTTCGCCATCCTCAAGCGCCAGCGCGAGCTTAG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TCCCTCGTATCCGGCTGCCACTTGCACCTCCTCGTATT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TAAATTGTCTATTTTTTCAATATTCGTTTCATCTA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CCACCACATGATCTGCGCCTGCGCCTCGTCGCCCCG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TCCAGTCGGACGGCCAGCGGTCCCACGAGCAAGGTCAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CCTGCCTTTCGCTAATGAGGGGCTGTCCGTACCGGAGGC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AAGGTGCTGAGGTGGTTCCTCTTCCAATAGTCGTGG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TCTGTTTCCGAAGCAATTAGGGAAATGGATGAGGTTT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGCAGCGTGAGATAAGCCAAATGCCGATCCTCGAAGA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	ATGTACGTCTCATAATGATGTCGCAAACGCGCTTAT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GGTCACGACCGCGCGGGCGTTGGCGATGCCGCTGTA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC

>NC_019940|4|3|1382797-1387045|CRT
CACGTAATAGGGCCGCGGCTATTCGCCGCGGAATTC	CCTTGGTCTCCGACCTGTGCGGACAATGTCTCGCCC
GCTTCAATGAGGCTACGGCTATTCGTCGCGGAATTC	GTCCACGCGAACTCCTCCGGCCAATGCAGGGTGGCCG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGGTCTTCCGCAAGCACTGCGCGCCCTTCTGGCGACCGT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTAGTCGATCGTGCCTTGCCCCTTGTAGCTCCTCCACA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CAACACCGACTGCACCCTCGCCACGTCGGCCGGATC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGTTCTTCCCGGAGACGTGGACCGTAGCCCTCGGCGA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TCACCCGCGAGCACGGCGGCACCACGCTGGCGCTACC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GGTCGCGACGGTCGGTGTGAAGATGGGGACGACGAG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TGTCAGACGGTCGGTTGCGCGGCCTGACGTATGTT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCACTGGCGCCGGCTAATCACCGCACAACCCCGCCAGC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	ACCGAAATGATAGGCGCCCATAACATGGCACCGGAT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AACAACAACCGCAACGGACGATGGAGTTTCTCGCGGA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CCTGCCCCTGCCCCGCGTCGCGCCTATCGAGCATCT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	ACAGTAAATGGCGAGTACGAAGAGGTGGCAACAGAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CCGTTGCCGCAACCGCCGGCGCCACGACGGCCCGCC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTCGTCGGCGTGGATGGCACCGGTCGCGTAGGACCA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AGCGCTGCCGGCAATCCACACGGGCGCCGTGCCGAA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTGTAGAGAGGCAGCACTGGATTATGTTCTGGCTCCAT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCTGGGCCGCGACCAAACCACAGAGTGGCCCCGGAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CAGAGCGTCCGTGAGCGGCTCGCTGAGGTCCGCAAGG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AATCAGGGATAAAAACGCTTCCGGCAACGGCTCAGGC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTCGCCGCCGTTGTCCCACTGGGTGTGCGCGGCATC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CCCGCTACGCCACCATCCGCGCCGCCTGGCGCGCCGT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCGGGGGAGAAGCACGGGCACAAATCGGATTACACGG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCCGAGAAGACGGCGGAGCTCAATGCCGAGCAGTC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCGTAGGATGGAGCGACAACTCTGGTGGTTGGGATT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	ATGCCAACGCCGTCGGCACCGGCATGAAGGTCTCTTACGA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTCGCCGACAAGGCTCAGCCGGGCAGCGCTCAATAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGCTGAACTCGACCACGGTGCGGTCGAAGCTGTAAG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TCCGCGGCCAATCGCCTGTTCAAGGAGGCCCTGCC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TTCCGCCCCTTGGTGCTCCAGCCGCGGGCTGGAGAA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTGTGGCAGGAGTTTGTTGATTTCCACGAGATTCGAAT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGGCGCCCACGGCTCGCCCCAGGGGCTGGTTTCGTTCTG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TGCGCGAATAGCGGCTTGAATTGATTTGGTACATTTT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AAAGCGAGGAACCTTGGCTATCGATTTCTCGCCGCT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AACATGTGCAGATTGAGCTGCTTGTCGCGGATCTGGGC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CTTGTCGGGCAAATACCCAACCGTTTTTATTACTCC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AGTGAAGGCACAATGCGATAAGGATAAGCTCCGCAA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGCCTGACCGATCTTGCGCCGAGGCATGACCGCCGAAG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	ACGATTCAAGCGCGCAATCCGAGCCAGCGGCGGTT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CTTACCGTGGGCTCTATTAATTTGGTCGAATCGTAAG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GGTTGGATTGGTGATGGCGTCGCCATTGCCAAGTAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TTCATCGGGGTACACCCAATTACCGCCGAACCGGTAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGGACGTGGCCATGGAATCCAGCCAGAATCCAGCCA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AACGAGCGATCGTCCCGCGCGGAGAGCCGTCGCGCT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCGTCCACACGGCCCGGCTCACCTGGAGTGAGCCGGA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTCGGAGTGATCAGATCCCCGGTAAAGCTGCCCTG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTTGTTCGCCATCCTCAAGCGCCAGCGCGAGCTTAG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TCCCTCGTATCCGGCTGCCACTTGCACCTCCTCGTATT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TAAATTGTCTATTTTTTCAATATTCGTTTCATCTA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CCACCACATGATCTGCGCCTGCGCCTCGTCGCCCCG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TCCAGTCGGACGGCCAGCGGTCCCACGAGCAAGGTCAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CCTGCCTTTCGCTAATGAGGGGCTGTCCGTACCGGAGGC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AAGGTGCTGAGGTGGTTCCTCTTCCAATAGTCGTGG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TCTGTTTCCGAAGCAATTAGGGAAATGGATGAGGTTT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGCAGCGTGAGATAAGCCAAATGCCGATCCTCGAAGA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	ATGTACGTCTCATAATGATGTCGCAAACGCGCTTAT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GGTCACGACCGCGCGGGCGTTGGCGATGCCGCTGTA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC

>NC_019940|4|4|1382869-1387045|PILER-CR
GCTTCAATGAGGCTACGGCTATTCGTCGCGGAATTC	GTCCACGCGAACTCCTCCGGCCAATGCAGGGTGGCCG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGGTCTTCCGCAAGCACTGCGCGCCCTTCTGGCGACCGT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTAGTCGATCGTGCCTTGCCCCTTGTAGCTCCTCCACA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CAACACCGACTGCACCCTCGCCACGTCGGCCGGATC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGTTCTTCCCGGAGACGTGGACCGTAGCCCTCGGCGA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TCACCCGCGAGCACGGCGGCACCACGCTGGCGCTACC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GGTCGCGACGGTCGGTGTGAAGATGGGGACGACGAG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TGTCAGACGGTCGGTTGCGCGGCCTGACGTATGTT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCACTGGCGCCGGCTAATCACCGCACAACCCCGCCAGC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	ACCGAAATGATAGGCGCCCATAACATGGCACCGGAT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AACAACAACCGCAACGGACGATGGAGTTTCTCGCGGA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CCTGCCCCTGCCCCGCGTCGCGCCTATCGAGCATCT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	ACAGTAAATGGCGAGTACGAAGAGGTGGCAACAGAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CCGTTGCCGCAACCGCCGGCGCCACGACGGCCCGCC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTCGTCGGCGTGGATGGCACCGGTCGCGTAGGACCA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AGCGCTGCCGGCAATCCACACGGGCGCCGTGCCGAA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTGTAGAGAGGCAGCACTGGATTATGTTCTGGCTCCAT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCTGGGCCGCGACCAAACCACAGAGTGGCCCCGGAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CAGAGCGTCCGTGAGCGGCTCGCTGAGGTCCGCAAGG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AATCAGGGATAAAAACGCTTCCGGCAACGGCTCAGGC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTCGCCGCCGTTGTCCCACTGGGTGTGCGCGGCATC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CCCGCTACGCCACCATCCGCGCCGCCTGGCGCGCCGT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCGGGGGAGAAGCACGGGCACAAATCGGATTACACGG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCCGAGAAGACGGCGGAGCTCAATGCCGAGCAGTC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCGTAGGATGGAGCGACAACTCTGGTGGTTGGGATT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	ATGCCAACGCCGTCGGCACCGGCATGAAGGTCTCTTACGA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTCGCCGACAAGGCTCAGCCGGGCAGCGCTCAATAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGCTGAACTCGACCACGGTGCGGTCGAAGCTGTAAG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TCCGCGGCCAATCGCCTGTTCAAGGAGGCCCTGCC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TTCCGCCCCTTGGTGCTCCAGCCGCGGGCTGGAGAA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTGTGGCAGGAGTTTGTTGATTTCCACGAGATTCGAAT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGGCGCCCACGGCTCGCCCCAGGGGCTGGTTTCGTTCTG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TGCGCGAATAGCGGCTTGAATTGATTTGGTACATTTT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AAAGCGAGGAACCTTGGCTATCGATTTCTCGCCGCT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AACATGTGCAGATTGAGCTGCTTGTCGCGGATCTGGGC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CTTGTCGGGCAAATACCCAACCGTTTTTATTACTCC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AGTGAAGGCACAATGCGATAAGGATAAGCTCCGCAA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGCCTGACCGATCTTGCGCCGAGGCATGACCGCCGAAG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	ACGATTCAAGCGCGCAATCCGAGCCAGCGGCGGTT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CTTACCGTGGGCTCTATTAATTTGGTCGAATCGTAAG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GGTTGGATTGGTGATGGCGTCGCCATTGCCAAGTAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TTCATCGGGGTACACCCAATTACCGCCGAACCGGTAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGGACGTGGCCATGGAATCCAGCCAGAATCCAGCCA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AACGAGCGATCGTCCCGCGCGGAGAGCCGTCGCGCT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GCGTCCACACGGCCCGGCTCACCTGGAGTGAGCCGGA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTCGGAGTGATCAGATCCCCGGTAAAGCTGCCCTG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GTTGTTCGCCATCCTCAAGCGCCAGCGCGAGCTTAG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TCCCTCGTATCCGGCTGCCACTTGCACCTCCTCGTATT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TAAATTGTCTATTTTTTCAATATTCGTTTCATCTA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CCACCACATGATCTGCGCCTGCGCCTCGTCGCCCCG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TCCAGTCGGACGGCCAGCGGTCCCACGAGCAAGGTCAC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CCTGCCTTTCGCTAATGAGGGGCTGTCCGTACCGGAGGC
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	AAGGTGCTGAGGTGGTTCCTCTTCCAATAGTCGTGG
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	TCTGTTTCCGAAGCAATTAGGGAAATGGATGAGGTTT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	CGCAGCGTGAGATAAGCCAAATGCCGATCCTCGAAGA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	ATGTACGTCTCATAATGATGTCGCAAACGCGCTTAT
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC	GGTCACGACCGCGCGGGCGTTGGCGATGCCGCTGTA
GCTTCAATGAGGCCGCGGCTATTCGCCGCGGAATTC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019940.1\|WP_015280212.1\|1377851_1378382_-\|RnfABCDGE-type-electron-transport-complex-subunit-B	unknown	unknown	gnl\|CDD\|235347
NC_019940.1\|WP_015280225.1\|1399053_1399290_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|226603
NC_019940.1\|WP_015280207.1\|1373526_1373790_-\|RnfH-family-protein	unknown	unknown	gnl\|CDD\|377094
NC_019940.1\|WP_015280223.1\|1397702_1398017_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379218
NC_019940.1\|WP_015280210.1\|1375205_1376303_-\|RnfABCDGE-type-electron-transport-complex-subunit-D	unknown	unknown	gnl\|CDD\|376991
NC_019940.1\|WP_015280214.1\|1379367_1381005_+\|nitrogen-fixation-negative-regulator-NifL	unknown	unknown	gnl\|CDD\|131984
NC_019940.1\|WP_015280217.1\|1387636_1389364_-\|CRISPR-associated-endonuclease-Cas4/Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_019940.1\|WP_015280209.1\|1374540_1375209_-\|electron-transport-complex-subunit-RsxG	unknown	unknown	gnl\|CDD\|273889
NC_019940.1\|WP_041604149.1\|1373830_1374520_-\|electron-transport-complex-subunit-E	unknown	unknown	gnl\|CDD\|237091
NC_019940.1\|WP_015280221.1\|1394999_1396217_-\|type-I-U-CRISPR-associated-protein-Cas7	csb1gr7	pfam09617_csb1gr7_CAS-I-U	gnl\|CDD\|378223
NC_019940.1\|WP_015280222.1\|1396324_1397314_-\|transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NC_019940.1\|WP_041603504.1\|1381025_1382612_+\|nif-specific-transcriptional-activator-NifA	unknown	unknown	gnl\|CDD\|273817
NC_019940.1\|WP_015280218.1\|1389441_1390365_-\|hypothetical-protein	cas8u1	mkCas0114_cas8u1_CAS-I-U	unknown
NC_019940.1\|WP_015280220.1\|1393347_1395000_-\|type-I-U-CRISPR-associated-protein-Cas5/Cas6	csb2gr5	cls000315_csb2gr5_CAS-I-U	gnl\|CDD\|274005
NC_019940.1\|WP_015280206.1\|1371955_1373401_+\|TrkH-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|182698
NC_019940.1\|WP_015280224.1\|1398670_1399057_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|350220
NC_019940.1\|WP_015280213.1\|1378413_1378995_-\|electron-transport-complex-subunit-RsxA	unknown	unknown	gnl\|CDD\|235352
NC_019940.1\|WP_015280211.1\|1376299_1377811_-\|electron-transport-complex-subunit-RsxC	unknown	unknown	gnl\|CDD\|273888
NC_019940.1\|WP_015280219.1\|1390361_1393355_-\|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09696_cas3_CAS-I-U	gnl\|CDD\|274235
NC_019940.1\|WP_015280216.1\|1387337_1387631_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856

Protein	Function_ID	Function_description	E-value
NC_019940.1\|WP_015280212.1\|1377851_1378382_-\|RnfABCDGE-type-electron-transport-complex-subunit-B	gnl\|CDD\|235347	PRK05113, PRK05113, electron transport complex protein RnfB; Provisional.	2.14679e-63
NC_019940.1\|WP_015280225.1\|1399053_1399290_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|226603	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning].	1.66765e-12
NC_019940.1\|WP_015280207.1\|1373526_1373790_-\|RnfH-family-protein	gnl\|CDD\|377094	pfam03658, Ub-RnfH, RnfH family Ubiquitin. A member of the RnfH family of the ubiquitin superfamily. Members of this family strongly co-occur in two distinct gene neighborhood contexts. In one it is associated with a START domain protein, a membrane protein SmpA and the transfer mRNA binding protein SmpB. This association suggests a possible role in the SmpB-tmRNA-based tagging and degadation system of bacteria, which is interesting given that other members of the ubiquitin system are analogously involved in protein-tagging and degradation across eukaryotes and various prokaryotes. The second context in which the RnfH genes are present is in a membrane associated complex involved in transporting electrons for various reductive reactions such as nitrogen fixation.	1.13716e-39
NC_019940.1\|WP_015280223.1\|1397702_1398017_-\|hypothetical-protein	gnl\|CDD\|379218	pfam13488, Gly-zipper_Omp, Glycine zipper.	4.43574e-08
NC_019940.1\|WP_015280210.1\|1375205_1376303_-\|RnfABCDGE-type-electron-transport-complex-subunit-D	gnl\|CDD\|376991	pfam03116, NQR2_RnfD_RnfE, NQR2, RnfD, RnfE family. This family of bacterial proteins includes a sodium-translocating NADH-ubiquinone oxidoreductase (i.e. a respiration linked sodium pump). In Vibrio cholerae, it negatively regulates the expression of virulence factors through inhibiting (by an unknown mechanism) the transcription of the transcriptional activator ToxT. The family also includes proteins involved in nitrogen fixation, RnfD and RnfE. The similarity of these proteins to NADH-ubiquinone oxidoreductases was previously noted.	2.47889e-132
NC_019940.1\|WP_015280214.1\|1379367_1381005_+\|nitrogen-fixation-negative-regulator-NifL	gnl\|CDD\|131984	TIGR02938, Nitrogen_fixation_regulatory_protein, nitrogen fixation negative regulator NifL. NifL is a modulator of the nitrogen fixation positive regulator protein NifA, and is therefore a negative regulator. It binds NifA. NifA and NifL are encoded by adjacent genes. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, Protein interactions].	1.31695e-163
NC_019940.1\|WP_015280217.1\|1387636_1389364_-\|CRISPR-associated-endonuclease-Cas4/Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	2.65976e-119
NC_019940.1\|WP_015280209.1\|1374540_1375209_-\|electron-transport-complex-subunit-RsxG	gnl\|CDD\|273889	TIGR01947, Electron_transport_complex_subunit_G, electron transport complex, RnfABCDGE type, G subunit. The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the A subunit. [Energy metabolism, Electron transport].	2.92038e-70
NC_019940.1\|WP_041604149.1\|1373830_1374520_-\|electron-transport-complex-subunit-E	gnl\|CDD\|237091	PRK12405, PRK12405, electron transport complex RsxE subunit; Provisional.	2.25475e-108
NC_019940.1\|WP_015280221.1\|1394999_1396217_-\|type-I-U-CRISPR-associated-protein-Cas7	gnl\|CDD\|378223	pfam09617, Cas_GSU0053, CRISPR-associated protein GSU0053 (Cas_GSU0053). This entry is found in CRISPR-associated (cas) proteins in the genomes of Geobacter sulfurreducens PCA and Desulfotalea psychrophila LSv54 (both Desulfobacterales from the Deltaproteobacteria), Gemmata obscuriglobus (a Planctomycete), and Actinomyces naeslundii MG1 (Actinobacteria).	4.55262e-62
NC_019940.1\|WP_015280222.1\|1396324_1397314_-\|transcriptional-regulator	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	5.26907e-41
NC_019940.1\|WP_041603504.1\|1381025_1382612_+\|nif-specific-transcriptional-activator-NifA	gnl\|CDD\|273817	TIGR01817, Nif-specific_regulatory_protein, Nif-specific regulatory protein. This model represents NifA, a DNA-binding regulatory protein for nitrogen fixation. The model produces scores between the trusted and noise cutoffs for a well-described NifA homolog in Aquifex aeolicus (which lacks nitrogenase), for transcriptional activators of alternative nitrogenases (VFe or FeFe instead of MoFe), and truncated forms. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, DNA interactions].	0
NC_019940.1\|WP_015280219.1\|1390361_1393355_-\|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|274235	TIGR02621, CRISPR-associated_helicase_Cas3, CRISPR-associated helicase Cas3, subtype Dpsyc. This model describes a CRISPR-associated putative DEAH-box helicase, or Cas3, of a subtype found in Actinomyces naeslundii MG1, Geobacter sulfurreducens PCA, Gemmata obscuriglobus UQM 2246, and Desulfotalea psychrophila. This protein includes both DEAH and HD motifs.	7.18576e-106
NC_019940.1\|WP_015280220.1\|1393347_1395000_-\|type-I-U-CRISPR-associated-protein-Cas5/Cas6	gnl\|CDD\|274005	TIGR02165, CRISPR-associated_protein_GSU0054_family, CRISPR-associated protein GSU0054/csb2, Dpsyc system. This model represents a CRISPR-associated protein from the Dpsyc subtype (a type I-C variant), named for Desulfotalea psychrophila LSv54. CRISPR systems confer resistance in prokaryotes to invasive DNA or RNA, including phage and plasmids. CRISPR-associated proteins typically are found near CRISPR repeats and other CRISPR-associated proteins, have low levels of sequence identify, have sequence relationships that suggest lateral transfer, and show some sequence similarity to DNA-active proteins such as helicases and repair proteins.	3.25073e-70
NC_019940.1\|WP_015280206.1\|1371955_1373401_+\|TrkH-family-potassium-uptake-protein	gnl\|CDD\|182698	PRK10750, PRK10750, Trk system potassium transporter TrkH.	3.44059e-171
NC_019940.1\|WP_015280224.1\|1398670_1399057_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|350220	cd09872, PIN_Sll0205-like, VapC-like PIN domain of Sll0205 protein and homologs. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of the Synechocystis sp. (strain PCC 6803) Sll0205 protein and other uncharacterized homologs are included in this subfamily. They are similar to the PIN domains of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	7.61695e-55
NC_019940.1\|WP_015280213.1\|1378413_1378995_-\|electron-transport-complex-subunit-RsxA	gnl\|CDD\|235352	PRK05151, PRK05151, electron transport complex protein RsxA; Provisional.	8.30552e-100
NC_019940.1\|WP_015280211.1\|1376299_1377811_-\|electron-transport-complex-subunit-RsxC	gnl\|CDD\|273888	TIGR01945, Electron_transport_complex_subunit_C, electron transport complex, RnfABCDGE type, C subunit. The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the C subunit. [Energy metabolism, Electron transport].	0
NC_019940.1\|WP_015280216.1\|1387337_1387631_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.32997e-20

>NC_019940.1|WP_041603504.1|1381025_1382612_+|nif-specific-transcriptional-activator-NifA
MSGAIETSGASEEMGRLDLLKSQLAALFEVSSILSRSLNLRETLCELLKVLHDHGRLRYGMVSLVDTESGDLLVSALHDSASDTFTTVRYRPGEGIIGRILERNEPWILPRVGDEPRFLDRLSLYDPNLPFIGVPIRVGEEGAVGVFAAQPQSADGLLDERARFLEMIANLIGQAVRLANRVAAEQQALREERDKLRRQVKGDHGFESIIGRAATMRLVFDQVRQVAKWNTTVLIRGESGTGKELVANAIHYNSPRARGAFVKLNCAALPDNLLESELFGHEKGAFTGAVSQRKGRFEQADGGTLFLDEIGEISPAFQAKLLRVLQEGEFERVGGNRTLKVDVRVIAATNRDLEAFVRSGEFREDLYYRLNVMPIRMPALRDRLEDVPDLARFLITKIARTQGRELDITDSALRVLMRYSWPGNVRELENCLERAAVMSETGVIDRDAIHLSGFGDGLDTDTPTALAPAAESAPKPDIDDPNLDERERVIAALEEAGWVQAKAARLLNMTPRQIAYRIQTLNIKVRQF
>NC_019940.1|WP_015280214.1|1379367_1381005_+|nitrogen-fixation-negative-regulator-NifL
MTSKGSSEPAQQLAANTLAAFLAAPPPGTPPEVIEALGLIGGESGEPLPPRLFFAAVEQSPVAISITNADAIILYANAAFEALTGYTRAEVVGKNESLLSNNATPSTIYRQLWRTIKNKRTWTGTLVNRTKAGGDYLAELTISPVLDQQGEIRYFLGMHRDVTQLHELEGALRQQKARVETVLDAAPILVVLLDGDGRVLLDNRECKKLQAELQGSEPIDLLRAALRKQAGFDPLEAALNGHGFKDVEVSLEIPGAGGPRWFACSGTPGHELEPSARNFFGHNTAGELRLLLLANDITARRREIERAHLENLRARLAEQQLSHTMREALGAAIYQIQGPLNVIHAASQMIKGGSANLTVLSGTLEQISAAGQKALETLEAALPAQPREAGLVVNVNALLREVLELETDRLLAAGIVVDWQPAHVLPEFNGHRTQLRSMFKLLIDNAIQALNESGKTHRELRVTTRVVESAVEVVIQDNGPGIPAEQRYEVFEPFYSGWRHRRGRAGMGLALAQEIVNLHGGSIEIDPEYLDGCRVRLLLTAAIDE
>NC_019940.1|WP_015280213.1|1378413_1378995_-|electron-transport-complex-subunit-RsxA
MTDYLLLILGTALVNNVVLVKFLGLCPFMGVSSKLDSAIGMGLATTFVLTLAAVASWLLEHFVLEPLGIGFLRILTFILVIAAVVQFTEMAVRKISPALYQVLGIFLPLITTNCAVLGVALLNVQGEYGFLESLLFGFGSALGFTLVMVLFAGMRERLALAQVPAAFAGAPIAFIAAGLLSLAFMGFAGLTHH
>NC_019940.1|WP_015280212.1|1377851_1378382_-|RnfABCDGE-type-electron-transport-complex-subunit-B
MIAPLLSLALLGLTLGTLLGVAARYLKVEQNPLQGEIEEMLPGSQCGQCGYPGCSAAAAAVAAGEAAVTMCPPGGRALVEQLAAKLGVSVDLAAIQDQGPRVAFIHERLCTGCTKCMKRCPTDAIIGASKMIHAVFPDACTGCNKCYEACPQECIEMRPLPVTVPQWYWPKPAPAL
>NC_019940.1|WP_015280211.1|1376299_1377811_-|electron-transport-complex-subunit-RsxC
MKLFKIRGGVHPEDRKALSGNQPIEPVALPHLLHVPLLQHVGAAANPAVRRGQTVRKGDLLAERQGVISAPVHAPTSGRVVGIGRYPANHPSGLSVPTITLQPDGEDRWSDELVGTEDPFALPPEEIAAEVAAAGIVGMGGATFPAAVKLNLRHRYRLHTLVINGSECEPYLTCDDRLMREQADQVLDGVRIMAHALGVGHIIIAIEGNKPEALAAMRRAVTGFAEVEVATLPTRYPMGSERHLVFTLTGRESPARGLTADIGIVVHNPATAFAVHEAVRYGRPLVERVVSITGAAVARPCNLRVPLGTPVDHLLEHCGGLREEPARLISGGPMMGQPLPSTRVPIVKGSNGVLALTAQEINRQEPMPCIRCGSCVSACPCGLMPLDLVARTRAADLEGAVRIGLMDCIGCGSCAYVCPAHIPLVQYINYAKGEMAARGRARHKQVETKRLSEQRTARMEAAKRAKREAMARRKKQQQAKAQAESEAPPPAGTETKPAAEARS
>NC_019940.1|WP_015280210.1|1375205_1376303_-|RnfABCDGE-type-electron-transport-complex-subunit-D
MSPLGDAPLIAGPFAHAQTSIGRTMRLVMLALIPGTLVGLWQFGWPAVNLFVVTIASAVVAETLALRLAGRPARPYLLDGSALLSGWLLSMTLPPWAPWWIGVVGGLIAIIIAKQVFGGLGQNLFNPAMVARVALLISFPVQMTTFVAPTPLFSADAPDFLGGLAITFGGQEYDALTSATVLGEVHTDLSTGLTLSDILPSTYQLNQAAIGTVAGSLGETSALLLLLGGLFLISRRVISWHIPMAMLVTITACATAMHLVDPSRFLNPGYHLLSGATVLAAFFIATDPVTAPVSARGRLLYGFGCGLLVYAIRTWSNYPEGAAFAVLLMNACTPLIDHYVRPRIYGRDRRGEPLSYGDDGREAAR
>NC_019940.1|WP_015280209.1|1374540_1375209_-|electron-transport-complex-subunit-RsxG
MSGASETGAGWREHISYQALLLGGFSLLAAALLTFGDLVTREPIAARRAEDLQASLSQVLPATIHDNDLLAAPLAMTDDDGEPLVVYRALRGLQVTGVAFRASAVGYAGPIEVLVGIDADGRILGARVLAHAETPGLGDKIEIDRDDWILDFDGRSIGDPPLERWAVAKDDGDFDQFTGATITPRAVVRAIKEALLYFAAHRDTLTASAVVTEPAPEAPRPR
>NC_019940.1|WP_041604149.1|1373830_1374520_-|electron-transport-complex-subunit-E
MSPDYGQIARDGLWNNNVVLSQALALCPLLAVTGTATNGLGMGLATTAVMTASGLLIALLRGLLSSAVRIPIFVLVIATLVTLVDLAMNAWLHDLHKVLGLFIPLIVTNCAILGRAESFAARQPALPAAFDGLMMGLGFTLVLVGLGAAREIIGSGTLFAGAPLLLGDAMAFLEVTLIPNYGGFLLAVLPPGGFLVLGFLLAGKRILDRRLAARRAAGGSATAAIMPRS
>NC_019940.1|WP_015280207.1|1373526_1373790_-|RnfH-family-protein
MHIGVAYADTLKQVWLKLDAPDGCTVHEAIERSGLLAQFPMIDLETQKVGIYGKITRLDAKVSDGDRVEIYRPIVAEIDTGEDEDDD
>NC_019940.1|WP_015280206.1|1371955_1373401_+|TrkH-family-potassium-uptake-protein
MNWRGVIRLIGILLTLYALSFIPPLLLALAYQDGEAPHFLAAWIISTAIGLAIWLPVRAERSALGYRDGFLVVALFWAVLGVVGSIPFIVGLHLGVTDAIFESVSGFTTTGATVIAGIDDLPPSILYHRQQIQWLGGMGVVILAVAILPLLGVGGMQLYRAEASGITKDEKLTPRITKTAQVLWSIYFALTLACTLAYWAAGMNLFDAVGHAFSTVSTAGFSTHDASIGYFDSLEIELICVVFMTLGGVNFAIHFVVWHRRNPLLYLRDPEVRTYLLILLGAILFIAISLLWFGTYTGVGEALRRSLFEVVSVITTTGFSTADFATWPRHIPLVLVMLAYVGGCAGSTAGGLKVVRVMLLAKMGVRQMFVLSHPRAMAPLKLGRRGVPEDAAYSIWGYYVLYLSTALVLTVAMMAAGLDLESAFGAVSATLNLLGPGLGDVATTFAAMSPLVKWLAIFGMLVGRLEVFTLLILFTFAFWRQ
>NC_019940.1|WP_015280216.1|1387337_1387631_-|CRISPR-associated-endonuclease-Cas2
MDQRLYIVTYDISDAKRWRRVFKIMKGYGDWLQLSVFQCRLTKTQHAELIALLDGIIHHTEDHIILLDLGLAEAVVPRVVSLGKRDYSPIEHEPIIV
>NC_019940.1|WP_015280217.1|1387636_1389364_-|CRISPR-associated-endonuclease-Cas4/Cas1
MAITDKEALTQAELPLPFPDLTLDQPLLPARMVNEFCYCPRLAYLEWVQGEWDESSDTVEGRHVHRRVDKPGGKLPAAEDAEPGERIHARSIQLSSNRLGLIARMDLVEGEGNRVTPVDYKRGKRPHIARGAYDPERVQLCVQGLILAEHGYQCESGILYYAASRERVVVPFDDELLQLTHNTIDGLRFVAAGGQIPPPLEDSPKCPRCSLVGICLPDEINFFRRADLTPRPLSVGIDTAMPVYVQAHHAKVTKSGERLEVFVEDQKVQSVRLIDVSQLVLFGNVYVTTPVLNELMSRGITISWHSFGGWFMGHSVGTGHKNVELRTAQYRASFDPALCLRFAKGLVEAKIRNSRTLLRRNWKGPFEPDILLEDLMGDCRHIKRITDLASLLGVEGSAASRYFSAFKHLIRQTDPADELAFDFQTRNRRPPTDPVNALLSYAYSLLARTWTVTLSAVGLDPYRGFYHQPRYGRPALALDMMEPFRPLIADSAVLQAINNGEVRPTDFVQAAGSVNLTPDGRKRFIATFERRMAHEITHPLFQYRLSYRRLLEVQARLLGRFLLGELPEYPNFTTR
>NC_019940.1|WP_015280218.1|1389441_1390365_-|hypothetical-protein
MSETLLLKGLDAGNPLGFLAALGVLTLSQAVAAEPRLAWRQAQGGWRPQLSGCGGDEEALASRLFEALRDTSSAPFAIDKKLPFSLLAFRDALRDAGEHAKPGNRRNADLLAAFGSDAHQDDKGNFVDTALRMVRSGDAAGQGLPAYAEAIRNNAEPNDLYRALFQDWDYQDDDFSLRWDPVEDQRYALRWYDPSPQSNKKYGLRTMRGANALALEGLALLPVQPKSNGVVTTGFKKLERGREAFTWPIWSYPATTDLVRSLLTLDEIHQSQPNRGNLHRRGIVEIYRSERIFQNQYYKNFSPARPV
>NC_019940.1|WP_015280219.1|1390361_1393355_-|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3
MTERPLTGQDFADFFAALWHQSPFPWQSALAERLLAPDGTVSGDESGWPQAITLPTASGKTACLDIALFALAAQAYRPAQGLTLTAPRRIFFVVDRRVIVDEAYARARMLAARLADPSPGILTEVAERLRGLAAGPANDETPDPLACFQLRGGIFRDDAWARSPTQPTIVCSTVDQIGSRLLFRAYGRSFKAWPLQAGLVGNDSLILLDEAHCAQPFMQTLEAVARYRRWAERPLASPFRLVVMTATPPAEVARFPDPATASANRAHLVLKRRLEASKPCRLEVAARAQGRDPARVNQALAEALVAEAGRLVEDYMSQADAQAPAVCLFCNRVDTARRAHALLARRHAGQAILLTGRMRPFDKNNTLETELAPLAADRAEQRQLAAPLFVVSTQTLEVGANLDFDLMVSECADLSALRQRFGRLNRMGRSIAARGVIVVRANQEKAESAPDPIYDRALQATWAWLAGQRDEAGEVDLGVAAIEARLPADLGPLTRQAVEAPVLLPAHLDALVQTAPVPCPSPDVSLFLHGPQAGPADVQVCWRADLSAEAEDAWIEAVALCPPATGELMPVPLAAIRRWLAGEPEGVDGGDIEGIAPAADDIEGVTERRVLRWRGREDAKVVGNPREIRPGDLLIIPAAAGGWDSLGHVPTGTRRFIDLGDRGHWESRARAILRLTPESLDAWPQELAARARLRELVDEAKTRLEEEPATLAADLKTALVDLSRDAEAASLPWLKDVAAHLASERHLERCIAPHPGRGLVLSSTRRLRNRPNTASIFSAEDDVTASGTVHWPLMDHLAGAAAWARHYTDQLPKKIADDIALAALCHDLGKADPRFQTLLQGGTIWTKPELLAKSASLPHGRQAYEEAREKAGYPKGGRHELLSVRLLESAPNLLAQAHDPELVRHLIESHHGHCRPFAPVVDDPGPDHPISLAFQGHVLAHDGPTGLDRLDSGVAERFWRLTRRYGWWGLAALAAALMLSDHRRSEWEERHASGDPT
>NC_019940.1|WP_015280220.1|1393347_1395000_-|type-I-U-CRISPR-associated-protein-Cas5/Cas6
MLALALHYLNGWAIAAADGARKQIAEWPPHPDRVFMALAAAHFEADGEDKAAERAALEWLERLPPPQLAVSEAEYRRVVTHYVPVNDTGLARAKTIAELAGASSTSLKALRAAGLGQLPELRPRQPRTFPVAIPHHPVVHLIWPDAEPTANQRNALARLCRQVTHVGHSASFVQMWLDETPPAASLIPSAGIAKHRLRIPSEGRLAYLEARVSRDRTVRFADQQGAIADLKRRIKMTKGKEKKALTSEIQACETALNAEFPAGAPVSLRPEPGLWQGYDEPPAAAPATTLGTLFDPNLVVLRLSGSRLSLRATLRLMEVVRGAVMARCPRQPPPEWLSGHTPDRQPSRAPHLAFLPLPFVGCPHADGRIMGAALALPKGLDPEEAAACLADLLYDQHGLPRAIPLFDGHWLDCTAEVETRTPAPQESLRTRVWTGPARRWASVTPVVLDRHFDGPDKWQRAADSVKTACERIGLPRPADVLLHPVSLFEGVPRSNEFPPITRKRDGGRMHHCHALILFDEPVGGPVLVGAGRFRGYGLCRPFVQGGDGHD
>NC_019940.1|WP_015280221.1|1394999_1396217_-|type-I-U-CRISPR-associated-protein-Cas7
MSLELETLKAAVAGNAAAFRCVTEYQPMGGPGDKVFPPTYEGGRYATEARVDPATDERVDCVLLDSVQSQANRMEQALLDAVEERGSLTLPLIRVAFTDVPKPIRVTSLDAPHRAADAIFRDSRIEEDGEWRAFRESSKGRILDHADLRNATGLFGLCPTALVFGLWDSTGPRGGLGAKFQRALVSEIVGYGAVEGKKTASRIDPLQIMLGAGPVYTAEDGGWTLSEAAAKKVKGKPVKIGKDGKPSEINHGNVTPSIADGGFTLTRAVQTTVLSLPTLRRLRFPLPDGAGAGQLAANQAARTALAALGLAAATLAREEGTDLRSRCQLFPTDPFVWALLDRPGETPTSFTLTGAEAVDLLNRALDEARQSGLPWEGIIDLTPSPDLVELVRRSQHLAAQADGED
>NC_019940.1|WP_015280222.1|1396324_1397314_-|transcriptional-regulator
MDTLTRISDLCRILEARRRPISLQDLMGQLECSESTARRAIHKLRDEFNAPIVFDQNAKGWYLDRTCNARTFRLPGHWLTAAELHALLSCHQLLRQIEPGLLGPEIAPLMEHIETTLAKHGLDRALLAERVRLVAIGARPVPSETLKAVAEALLSGHRLQVTYHSRSRDEIRERTLSLQRLTWYRSNWYLEAWCHQSGGPRRFAVERLLSARPLATAAEPIPTADLDAHFADAYGIFAGLATQTATLLFSRERARWVADERWHPHQRGRHLPDGRYELTLPYGRADELIMDILKYGPDVEVIAPTELRDAVAGRLEEAAKRYRRHLVRF
>NC_019940.1|WP_015280223.1|1397702_1398017_-|hypothetical-protein
MKPQTLALTTLLSIVLVGCGTTTAERTGSGAAAGAATGALIGSMSGNAGEGALIGAGAGAVGGYLYDQNEKRKGYYRDDDYYRDDDYYRDRDHRRDDDYYYRSY
>NC_019940.1|WP_015280224.1|1398670_1399057_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MRVLLDTHAFLWWVTDDPRLSADARATIGDEANGILVSAASAWEIATKHRLGKLGSAAGAVARFGELVAADGFEHLAVSYLHALKAGSYPAVHRDPFDRMLAAQSELERAPLITRDPTFEEFGTRTLW
>NC_019940.1|WP_015280225.1|1399053_1399290_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MTLTVNVHEAKTHFSRLLEQAHAGQEIILAKAGKPYARLMPLAPTSGRRRPGRLAGRLSDAFFEPLPEEELAAWDEDA

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Crispr_ID: NC_019940_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019940_5

2197736-2197830

Orphan

Consensus_repeat	Method
CGACTCGCCGGGAGATCCGCGAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019940_5

>merge|NC_019940|5|2197736-2197830|CRISPRCasFinder
CGACTCGCCGGGAGATCCGCGAGCAGATCTTCAATCTCGGCACACCGCACGGCCCGGCCGATACCAAGACGACGACTCACCGGGAGATCCGCGAG

>NC_019940|5|5|2197736-2197830|CRISPRCasFinder
CGACTCGCCGGGAGATCCGCGAG	CAGATCTTCAATCTCGGCACACCGCACGGCCCGGCCGATACCAAGACGA
CGACTCACCGGGAGATCCGCGAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019940.1\|WP_015280886.1\|2194419_2195634_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_019940.1\|WP_015280894.1\|2203016_2203337_+\|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|224583
NC_019940.1\|WP_015280885.1\|2191276_2194423_-\|multidrug-efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|273335
NC_019940.1\|WP_015280879.1\|2184934_2185435_-\|disulfide-bond-formation-protein-B	unknown	unknown	gnl\|CDD\|376848
NC_019940.1\|WP_015280888.1\|2197356_2197557_+\|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin	unknown	unknown	gnl\|CDD\|226603
NC_019940.1\|WP_015280895.1\|2203329_2203692_+\|DUF86-domain-containing-protein	unknown	unknown	gnl\|CDD\|225236
NC_019940.1\|WP_015280896.1\|2203688_2205425_+\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|341145
NC_019940.1\|WP_015280881.1\|2186582_2187998_+\|decarboxylating-NADP(+)-dependent-phosphogluconate-dehydrogenase	unknown	unknown	gnl\|CDD\|236453
NC_019940.1\|WP_015280892.1\|2202188_2202464_+\|BrnT-family-toxin	unknown	unknown	gnl\|CDD\|367913
NC_019940.1\|WP_041603645.1\|2198173_2200630_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|226581
NC_019940.1\|WP_015280883.1\|2189400_2190468_-\|hypothetical-protein	unknown	unknown	unknown
NC_019940.1\|WP_015280887.1\|2196405_2197188_+\|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl\|CDD\|213023
NC_019940.1\|WP_015280897.1\|2205638_2205866_+\|DUF433-domain-containing-protein	unknown	unknown	gnl\|CDD\|225291
NC_019940.1\|WP_015280884.1\|2190505_2190796_-\|hypothetical-protein	unknown	unknown	unknown
NC_019940.1\|WP_157633848.1\|2185485_2186277_-\|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl\|CDD\|381594
NC_019940.1\|WP_015280898.1\|2205865_2206132_+\|DUF5615-family-PIN-like-protein	unknown	unknown	gnl\|CDD\|375906
NC_019940.1\|WP_015280891.1\|2200633_2202082_+\|SAM-dependent-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|223363
NC_019940.1\|WP_015280893.1\|2202460_2202733_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227620
NC_019940.1\|WP_157633849.1\|2188280_2189336_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340839
NC_019940.1\|WP_051021898.1\|2206164_2206395_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226981

Protein	Function_ID	Function_description	E-value
NC_019940.1\|WP_015280886.1\|2194419_2195634_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	5.86911e-71
NC_019940.1\|WP_015280894.1\|2203016_2203337_+\|nucleotidyltransferase-domain-containing-protein	gnl\|CDD\|224583	COG1669, COG1669, Predicted nucleotidyltransferases [General function prediction only].	8.28215e-13
NC_019940.1\|WP_015280896.1\|2203688_2205425_+\|restriction-endonuclease-subunit-S	gnl\|CDD\|341145	cd17256, RMtype1_S_EcoJA65PI-TRD1-CR1_like, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to S.EcoJA65PI TRD1-CR1, S.Fco49512ORF2615P TRD1-CR1, and S.SonIV TRD2-CR2. Escherichia coli UCD_JA65_pb S subunit (S.EcoJA65PI) recognizes 5'... AGCANNNNNNTGA ... 3' while Shewanella oneidensis MR-1 S subunit (S.SonIV) recognizes 5'... TACNNNNNNGTNGT ... 3'. The recognition sequence of Flavobacterium columnare S subunit (S.Fco49512ORF2615P) is undetermined. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. For example, S.EcoJA65PI TRD1 recognizes AGCA/TGCT and S.EcoJA65PI TRD2 recognizes TCA/TGA; S.SonIV TRD1 recognizes TAC/GTA and S.SonIV TRD2 recognizes ACNAC/GTNGT. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	5.54316e-74
NC_019940.1\|WP_015280885.1\|2191276_2194423_-\|multidrug-efflux-RND-transporter-permease-subunit	gnl\|CDD\|273335	TIGR00915, Probable_aminoglycoside_efflux_pump, The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate].	0
NC_019940.1\|WP_015280879.1\|2184934_2185435_-\|disulfide-bond-formation-protein-B	gnl\|CDD\|376848	pfam02600, DsbB, Disulfide bond formation protein DsbB. This family consists of disulfide bond formation protein DsbB from bacteria. The DsbB protein oxidizes the periplasmic protein DsbA which in turn oxidizes cysteines in other periplasmic proteins in order to make disulfide bonds. DsbB acts as a redox potential transducer across the cytoplasmic membrane and is an integral membrane protein. DsbB posses six cysteines four of which are necessary for it proper function in vivo.	7.25915e-29
NC_019940.1\|WP_157633849.1\|2188280_2189336_+\|glycosyltransferase	gnl\|CDD\|340839	cd03811, GT4_GT28_WabH-like, family 4 and family 28 glycosyltransferases similar to Klebsiella WabH. This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.	1.49871e-78
NC_019940.1\|WP_015280895.1\|2203329_2203692_+\|DUF86-domain-containing-protein	gnl\|CDD\|225236	COG2361, COG2361, Uncharacterized conserved protein [Function unknown].	2.03453e-30
NC_019940.1\|WP_015280888.1\|2197356_2197557_+\|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin	gnl\|CDD\|226603	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning].	2.7775e-07
NC_019940.1\|WP_015280881.1\|2186582_2187998_+\|decarboxylating-NADP(+)-dependent-phosphogluconate-dehydrogenase	gnl\|CDD\|236453	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase.	0
NC_019940.1\|WP_015280892.1\|2202188_2202464_+\|BrnT-family-toxin	gnl\|CDD\|367913	pfam04365, BrnT_toxin, Ribonuclease toxin, BrnT, of type II toxin-antitoxin system. BrnT is a ribonuclease toxin of a type II toxin-antitoxin system that exhibits a RelE-like fold. The antitoxin that neutralizes this toxin is pfam14384. BrnT is found in bacteria, archaea, bacteriophage, and plasmids. BrnT-BrnA forms a 2:2 tetrameric complex and autoregulates its own expression, which is induced by a number of different environmental stresses. Expression of BrnT alone results in cessation of bacterial growth which can be rescued after subsequent expression of BrnA.	1.89443e-07
NC_019940.1\|WP_041603645.1\|2198173_2200630_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|226581	COG4096, HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	0
NC_019940.1\|WP_015280887.1\|2196405_2197188_+\|polysaccharide-deacetylase-family-protein	gnl\|CDD\|213023	cd10918, CE4_NodB_like_5s_6s, Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands. This family belongs to the large and functionally diverse carbohydrate esterase 4 (CE4) superfamily, whose members show strong sequence similarity with some variability due to their distinct carbohydrate substrates. It includes bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, hemin storage system HmsF protein in gram-negative species, intercellular adhesion proteins IcaB, and many uncharacterized prokaryotic polysaccharide deacetylases. It also includes a putative polysaccharide deacetylase YxkH encoded by the Bacillus subtilis yxkH gene, which is one of six polysaccharide deacetylase gene homologs present in the Bacillus subtilis genome. Sequence comparison shows all family members contain a conserved domain similar to the catalytic NodB homology domain of rhizobial NodB-like proteins, which consists of a deformed (beta/alpha)8 barrel fold with 6 or 7 strands. However, in this family, most proteins have 5 strands and some have 6 strands. Moreover, long insertions are found in many family members, whose function remains unknown.	1.177e-56
NC_019940.1\|WP_015280897.1\|2205638_2205866_+\|DUF433-domain-containing-protein	gnl\|CDD\|225291	COG2442, COG2442, Uncharacterized conserved protein [Function unknown].	1.11596e-23
NC_019940.1\|WP_051021898.1\|2206164_2206395_+\|hypothetical-protein	gnl\|CDD\|226981	COG4634, COG4634, Uncharacterized protein conserved in bacteria [Function unknown].	9.0468e-06
NC_019940.1\|WP_157633848.1\|2185485_2186277_-\|transglycosylase-SLT-domain-containing-protein	gnl\|CDD\|381594	cd00254, LT-like, lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.	1.12948e-48
NC_019940.1\|WP_015280898.1\|2205865_2206132_+\|DUF5615-family-PIN-like-protein	gnl\|CDD\|375906	pfam18480, DUF5615, Domain of unknown function (DUF5615). This is a domain of unknown function found in potential toxin-antitoxin system component.	9.31014e-10
NC_019940.1\|WP_015280891.1\|2200633_2202082_+\|SAM-dependent-DNA-methyltransferase	gnl\|CDD\|223363	COG0286, HsdM, Type I restriction-modification system methyltransferase subunit [Defense mechanisms].	7.61121e-93
NC_019940.1\|WP_015280893.1\|2202460_2202733_+\|hypothetical-protein	gnl\|CDD\|227620	COG5304, COG5304, Uncharacterized protein conserved in bacteria [Function unknown].	9.94732e-12

>NC_019940.1|WP_015280888.1|2197356_2197557_+|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin
MRHQVNVHEAKSRLSRLIASAEAGEEVIIARANKPFARLRAELSTRAQGALTPSPEQLIREEREAR
>NC_019940.1|WP_015280887.1|2196405_2197188_+|polysaccharide-deacetylase-family-protein
MQHRPPRHISILMYHQVGVFAPMKSHRANYCDHRRFAAQMALLARLNWTVLNLDQALACLRGDVPTPRRALVLTFDDAYENFADYALPVLQRHGFPATVYAISGWLGRRADWFAKDPGRPIPRLMSGARLRELRAADITIGSHSANHVKLGETDPRTRRAELRDSKAALEDLLGEPVRHLGYPFGSFDLDTVRAAAETGYASATTCLRGAACPTDHPLALPRKAISFGDDLIGFWWKLAIKNAPKPALTAWRQRLAVEPR
>NC_019940.1|WP_015280886.1|2194419_2195634_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MEKILGFSAATRSAALPGSNRGTVPSRWWLERLAIGLILPLVMLSGCDGGAPPPAAPPPPSVVAVAAKAQPIKKESQFVGRVRAIDRVELRARVEGFLKERSFTEGQQVAVGDVLFLIEPDQYAAVVAQRAADLEKARADSQNADAQLARALELLKKNNIARAKVDELEAAASVAKASIAQAEAALTAAELDLGYTRITAPVAGRIGLSQYTVGNLVGPSSGVLATIVSRDPINVEFPVTQRELLEARRAITAKGGDVRRILVRARLADDSLYGHPGHLDFVDVTTDQSTDSVTLRAQLPNPDGILVDGQYVGVVVEAAEAQEAILVPQSALQLDQEGTFVLVVADGKAQTRRVETGASRGNDIIVSSGLKEGDLVITEGIQKVRPGQAVSVAPARRPGGDAAP
>NC_019940.1|WP_015280885.1|2191276_2194423_-|multidrug-efflux-RND-transporter-permease-subunit
MISATFIDRPRLSIVISVVLTLAGLIAITQIPVAQFPDIVPPQVSVTTAYPGASAAVVESTVAQPLESKVNGVDDMLYMKSSSANDGSYTLTVSFALGTDPDLNTVNVQNRVNQALAQLPEEVTRTGVTVQKQSSALLQVITLTSPKGSYDALFLSNYATINVIDTLARVDGVGKAALFAPRDYSMRIWLSSDRLTSLGLTPSDVIGAIQAQNVQAAVGRIGAQPMTADQQFQITLQTKGRLSDVAEFERIVVRANPDGSTVRVKDVGTVELAAKSADATMRLDGAPTAAIGIYQAPGANAVAVANAVKAAMDDLAERFPDDLDYGVMYDTTDFVNASIEKVIHTLFEAFALVILVVFLFLGSWRATLIPLVAVPVALVGTFAFLLAIGFSANTISLLAVVLAIGIVVDDAIIVVENVERIMEEEGLGPREAAKKAMDQISGAIIAISLVLLSVFLPVAFIPGITGQLFQQFAAVVAFSMLISAINALTLSPALCAILLKPNSHRRGPLAAVMRGIDGVCNGYAHIVARLVRIALLVLVLIAVIGLATGWLFKVTPTGFLPEEDQGAFMAEIQLPQGASLTRTLGVVAQVEQIVMADPAVEQVFTVPGYSILDGAVESNAALLIGRLKPFEERETADLKVQAVIARVGAQTAAIPSSLVMPFNLPPIMGLGTSGGFEYQLEDLQGREPQALAAVMRSLVLAANQEPPLQRVFSTWATNNPQVYLDFDREKAQTLGVQISDVFTALQATLGGYYVNDFNKFGRTWQVQLQGREGDRERFADVYRIHVRNDQGEMVPVRAFMTPQLILGPQLIQRYNNYRSVTVQGNPAPGYSSGDALAAMEAVSDKTLPAGYGYEWTGTSQQEKEAGGKTPIVLGLAMLFAYLFLVALYESWSMPVAVLLSVSVGLLGAMLALWVAGLPNDLYAQVGIVVLIGLASKNAILIVEFAMEQRGDGFSIREAATKAARLRIRAVLMTSFAFILGLVPLIIASGAGEASQRGVGTAVFGGMLAAALVGVFLIPMLYVVFQQLREKLHGGATTRGRMESSSPAA
>NC_019940.1|WP_015280884.1|2190505_2190796_-|hypothetical-protein
MTDNDVDVGVITVLLERLRTQRLPRLLDLKAKVDRGERLDDYDLQFLERVFDDAGRNKALFTRHPELTEIGSKMVGLFHAITSKALENENSDPSRS
>NC_019940.1|WP_015280883.1|2189400_2190468_-|hypothetical-protein
MTGRLVDLWAGLREARARRRADETWRRQDARRVRAAVERVVDRANPQLRALGGYRRRLEGVVRPALDYCRSLAETIPGPVVLDRRQWMADPLVNALFGSPQRLRSALTNTTVCRFLKEMPSSTDDCYALLLATPTIRNQTGVGLIGSTLRRDVPQATLSFSDHRVILPSFDLAGLRANIERAGLDALVGAAVAELVEHERRIAELEDRLRIVRLKHRVTRAPDLDLDLVGEPAVAQHAEHLALGERIADLERQLGEARRGFVGLDDYLSRLAELLGDPAHLIGTTREQVRVDRMNVIRRPNEPQQAAELDLVRGRRGGKVGRVMLMVRFPRAELISEEERSAAFDRYVNASRPRH
>NC_019940.1|WP_157633849.1|2188280_2189336_+|glycosyltransferase
MIVNLIRGLVDLGRDVDLLPVRRRSPHLDRLPPAVRCLPMGVEHTLLAVPALAGYLRRQRPAALLAAKDRAGRAAVLARALAGTETPIVLRLGTHLSTAMAGKTGLERQLRYAPIRQLYRHLDHIVAVSEGVAADTAAITGLPRSRITVIRNPVITPELAAQGAALCAHPWLQPGGPPVIVGAGRLDRQKDFPTLLRAFARLRATRPCRLVILGNGRDRAALEELARELAITADLDLPGFQTNPYPFMARARLFVLSSAWEGSPNVLTEAMALGTPVVSTDCPSGPAELLDQGRYGPLVPVGDAAALADAMAATLDAPLPATRLQAAVAEYDQAIAARRYLAAMMSADGPG
>NC_019940.1|WP_015280881.1|2186582_2187998_+|decarboxylating-NADP(+)-dependent-phosphogluconate-dehydrogenase
MSDAEIGIIGLAVMGQNLALNMDDHGFRVAVFNRTAAKVDAFLAGPAAGTPIIGCQSLHDLVAALERPRRILMMVRAGAAVDDMITEIAPHLSPGDSLIDGGNSHFRDTERRAGALAAQGIRYVGAGISGGEDGARHGPAIMPGGDPQAWPLVKDLFQTIAAQVDGTPCCQWIGDGGAGHYVKMVHNGIEYADMQLIAEAYLLLRAGVGLGVDEIQSVFADWGEGILNSYLIEITAEILKVKDDDGSPLIDKVLDRAAQKGTGSWTAINALELGVPATLIGEAVFARSLSAMKDERVRAAARLPAAPLSSSIASTDFVDRIHDALYAAKICSYAQGFLLLREAANTHGWKLDLGGIALLWRGGCIIRSGFLNDIKAAYDETPEPESLLQHDFFRLELERTLPNWRKTVAMAIGLGIPTPALASALTFYDGYRSADLSANLIQAQRDYFGAHTYERTDQPRGKAFHSDWDSG
>NC_019940.1|WP_157633848.1|2185485_2186277_-|transglycosylase-SLT-domain-containing-protein
MLIAAVLPTAVGAGERLPTFDEIYRSQHAEELTAWGRRYERGVGVAQDTKKAVQLYCRAAAKGDRDAKYYMGQLLAFGRGIDHDKDLAAAWLHAAAEAGDRRSRNMLMVLNVGDKPTRRAVCPLGSGSVTRIASRSHPAQGAIADLVRRLAPSYGLDPELVLAVIETESNFNPNARSSKNAQGLMQLIPATAARFGVEDTWDPEQNLRGGMAYLSWLLKHFGGDVELALAGYNAGEGAVERHGGIPPYRETRNYVSRIVSRIN
>NC_019940.1|WP_015280879.1|2184934_2185435_-|disulfide-bond-formation-protein-B
MSQGRARIVWAALAAVSVGAVAVSLAVTEWRFLEPCHLCIFQRLLFMLLAVSTGIATLGGAHLVGRVAGALAALVAALGVGVATYQSWLQHEAVESLVSCTGGEPGPIERLVEWLGERWPTLFMPSGFCDDPGATFLGLSLANWSLIAFAACLLAAVWGIWRTLHV
>NC_019940.1|WP_041603645.1|2198173_2200630_+|DEAD/DEAH-box-helicase-family-protein
MDKRSLSERDICTKFITPALRHAGWDEMSQIREEVSFTKGRIIVRGKLVTRGQAKRADYILYYRPNLPLALIEAKDNAHSVGDGMQQALDYAQTLNIPFVFSSNGDSFVFHDRTGGSDPRETTLPLDAFPSPADLWARFRAWKGLDAEAESVVLQDYHDDGSGKTPRYYQVNAINAAIEAIAKGRRRVLLVMATGTGKTYTAFQIIWRLWKAGRSKRILFLADRNVLIDQTMVNDFRPFGGTMAKLSTNAKTIERGDGSTDDLTLALDKRRRIDTAYEVYLGLYQAITGPEESQKLFREFSPGFFDLIVIDECHRGSAAEDSAWREILEYFSAATQIGLTATPKETQYVSNIAYFGEPVFTYSLKQGIRDGFLAPYKVVKVHIDRDVEGYRPEKGQLDRVGEEVEDRLYNIKDFDRTLVIDDRTRLVAQKVTQFLKESGDRYQKTILFCVDQEHAARLRQALTNENADLVAENPRYVMRITGGDAEGQAQLGNFIDPEARWPVLVTTSRLLSTGVDAQTCRLIVLDREVGSMTEFKQIVGRGTRVHEDTRKYYFTLIDFRGATSHFADPDFDGEPVQIYAPKDGQPIDPPDAPPTDEDGLPLPESPGDDETIVDRPGVDQPDLPPPTGGPRRKVYVDGVGASIVAERVEYLDEHGRLVTESLRDFTKRALRKRFASLDDFLRRWNAAERKQAILEELEAEGLPLDPIVAELGRDLDPFDLICHVAFDAKPLTRRERAEHVKKRDAFTKYGPKARAVLDALLAKYADEGVLNLDDANVLRIAPFSGLGTPIELIRAFGGKPSFERAVHDLQSELYRDTA
>NC_019940.1|WP_015280891.1|2200633_2202082_+|SAM-dependent-DNA-methyltransferase
MSVRTLVKSIQDIMWKDVGVDGDAQRISQLCWMLFLKIIDDQDQELELLKDGYRSPIPARLQWRAWAADPEGITGEALLDFVNDDLFPMLKGLAPRTPRARTVRDVFEDAYNYMKSGQLMRQVVNKIDGIDFNNLTERQHFGDIYEQILNDLQSAGNAGEFYTPRAVTAFMVRMTDPQPGETLFDPACGTGGFLTCAIRHMREHSVKRPEDEARMQSSLRAVEKKQLPHMLAVTNMLLHGIEDPSFLRHDNTLARPYISWGKDERVDIVLTNPPFGGREEDGIESNFPQHFRTRETADLFLALIIRLLKPGGRAAVVLPDGSLFGEGVKTRLKEHLMAECNLHTIVRLPNSVFRPYASIGTNLLFFEKGAPTRDIWFWEHQVPEGQKAYSMTRPIRLDHLADCAAWWGGPRREGRQETERAWKVTASEVKARGYNLDIKNPHTVAEDHGDPETLLKELTSAEAEVAMIRDELKAILSEALLR
>NC_019940.1|WP_015280892.1|2202188_2202464_+|BrnT-family-toxin
MKPINWDPEKNRQLQQEQHVSFEDVVFHISAGGILDTLDHPNQERYPGQQIHVIEMEGYVYLVPFVESDDEVFLKTIIPSRKATKTYLGSR
>NC_019940.1|WP_015280893.1|2202460_2202733_+|hypothetical-protein
MSRLDQNEHELLEAFEAGELKRAPNATEIQQRHREYAEAMFKKDARINIRLSSKDLRGLQKKALAEGMPYQTLVASILHKYVEGRLREDR
>NC_019940.1|WP_015280894.1|2203016_2203337_+|nucleotidyltransferase-domain-containing-protein
MHPSIAQKAPEIAALCRRYRVQRLDLFGSAARGSDFDPVSSDADFLVEFEDDGGTSSPLRRILGLEQDLEQLLQRPVDLIERRALENSRNYIRRRSILRGAKSIYG
>NC_019940.1|WP_015280895.1|2203329_2203692_+|DUF86-domain-containing-protein
MADIPERDAALLLDMLLAARDALEFTDGLTKERFLSSRLHQNAIIRSLEVIGEAAGRVSTESTSTLPVIPWRAVTGMRHRLIHGYATVDLEMVWEVVNEEIAPLIDILEPLVPADDDTDE
>NC_019940.1|WP_015280896.1|2203688_2205425_+|restriction-endonuclease-subunit-S
MNAERLLTRYDRIADASNAIARLRRFVLDLAVRGKLVEQDPADEPASELLKRIAAEKARLVKAGEIRKTKAVPSLEPDGLPFPLPHGWAWTQIAEIGVISPRNEAPDDLEASFVPMPMIAAEYGEANGHEPRQWGEIKKGYIHFAEGDVGLAKITPCFENGKSTVFRNLIGGIGAGTTELHVVRPLFVDADYIVLFLKSPYFIQTGIPKMTGTAGQKRVPKEYFTTSPFPLPPLAEQRRIVAKVDELMALLDRLEAARTAREATRDRLTAASLARLTAPDTEPETFPNDARFAIATLPALTARADQIKPLRQAIINLAVRGKLVEQDPADEPASVLLDRAKKAKKALREERRIGRSEGPEYSESPGEASAPRHWSWSYLADFAMVLGGKRLPAGTSFSKEPTEHIYIRVTDMKGGTISDDGIKFISPEVQNKIAKYTIDQEDIYITIAGTIAEVGMVPALFHGQNLTENAAKIVFREVDRGFLILALRSNDVQSQFAEKTKQMAQPKLALKRILGARVPLPPLAEQHRIVAKVDALMTLCDRLETALAQADATRARLLEALLHEALAPAADLVAEAAA
>NC_019940.1|WP_015280897.1|2205638_2205866_+|DUF433-domain-containing-protein
MLNLDRITLDPDICHGKPCIRHMRWPVDVVLDLLSSGMSIDDILADHPELEREDITACLQYARLLASGEPIQRVA
>NC_019940.1|WP_015280898.1|2205865_2206132_+|DUF5615-family-PIN-like-protein
MRVLCDVHIPYRLVNRLRDLGVDATHVNRILDGSRTKDSAIAAYGDLEKLPSGQFFKTRSENAISASLHFQSLRRLKMAGHPCPAQAP
>NC_019940.1|WP_051021898.1|2206164_2206395_+|hypothetical-protein
MLLITKDGDFRDRHFLTGTPARVLRVTLGNLSNTELIALVEASWNAIAESCREQACYLELSRAGVVRLPHEGSRIK

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Crispr_ID: NC_019940_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019940_6

2302148-2302253

Orphan

Consensus_repeat	Method
GTGCGCATGAGGAGCGCCCAGGCAAGCTACGGACCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019940_6

>merge|NC_019940|6|2302148-2302253|CRISPRCasFinder
GTGCGCATGAGGAGCGCCCAGGCAAGCTACGGACCGTGGCTGCCCAATTTCCACCGCGTAGTAATACGGCGTGCGCATGAGGAGCGCCCAGGCAAGCTACGGACCG

>NC_019940|6|6|2302148-2302253|CRISPRCasFinder
GTGCGCATGAGGAGCGCCCAGGCAAGCTACGGACCG	TGGCTGCCCAATTTCCACCGCGTAGTAATACGGC
GTGCGCATGAGGAGCGCCCAGGCAAGCTACGGACCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019940.1\|WP_015280965.1\|2293956_2295042_+\|beta-N-acetylhexosaminidase	unknown	unknown	gnl\|CDD\|235417
NC_019940.1\|WP_157633726.1\|2297741_2298821_+\|FAD:protein-FMN-transferase	unknown	unknown	gnl\|CDD\|224394
NC_019940.1\|WP_015280976.1\|2306461_2307931_+\|ATP-dependent-RNA-helicase-RhlB	unknown	unknown	gnl\|CDD\|235314
NC_019940.1\|WP_015280981.1\|2313012_2314113_+\|alkene-reductase	unknown	unknown	gnl\|CDD\|239243
NC_019940.1\|WP_015280980.1\|2311912_2312863_+\|AEC-family-transporter	unknown	unknown	gnl\|CDD\|223751
NC_019940.1\|WP_015280978.1\|2309115_2309700_+\|ADP-compounds-hydrolase-NudE	unknown	unknown	gnl\|CDD\|183303
NC_019940.1\|WP_157633727.1\|2298918_2299869_+\|pseudouridine-synthase	unknown	unknown	gnl\|CDD\|182659
NC_019940.1\|WP_015280964.1\|2292752_2293565_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NC_019940.1\|WP_015280967.1\|2295816_2296266_+\|hemerythrin-domain-containing-protein	unknown	unknown	gnl\|CDD\|376622
NC_019940.1\|WP_015280971.1\|2300151_2301561_+\|glutamate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234953
NC_019940.1\|WP_083884797.1\|2301576_2301747_+\|nucleotidyltransferase-substrate-binding-protein	unknown	unknown	gnl\|CDD\|378048
NC_019940.1\|WP_015280972.1\|2301728_2301983_+\|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|376187
NC_019940.1\|WP_041604340.1\|2296929_2297706_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|236122
NC_019940.1\|WP_015280979.1\|2310116_2311865_+\|chloride-channel-protein	unknown	unknown	gnl\|CDD\|238233
NC_019940.1\|WP_015280973.1\|2302493_2304179_+\|glutamine--tRNA-ligase/YqeY-domain-fusion-protein	unknown	unknown	gnl\|CDD\|235424
NC_019940.1\|WP_015280974.1\|2304486_2305743_-\|transcription-termination-factor-Rho	unknown	unknown	gnl\|CDD\|236490
NC_019940.1\|WP_015280975.1\|2305927_2306254_-\|thioredoxin-TrxA	unknown	unknown	gnl\|CDD\|181812
NC_019940.1\|WP_051022008.1\|2308032_2308668_-\|GMP/IMP-nucleotidase	unknown	unknown	gnl\|CDD\|237882
NC_019940.1\|WP_015280982.1\|2314180_2315143_-\|hypothetical-protein	unknown	unknown	unknown
NC_019940.1\|WP_015280966.1\|2295028_2295586_+\|hypoxanthine-guanine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181675

Protein	Function_ID	Function_description	E-value
NC_019940.1\|WP_015280965.1\|2293956_2295042_+\|beta-N-acetylhexosaminidase	gnl\|CDD\|235417	PRK05337, PRK05337, beta-hexosaminidase; Provisional.	0
NC_019940.1\|WP_157633726.1\|2297741_2298821_+\|FAD:protein-FMN-transferase	gnl\|CDD\|224394	COG1477, ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism].	9.76789e-115
NC_019940.1\|WP_015280976.1\|2306461_2307931_+\|ATP-dependent-RNA-helicase-RhlB	gnl\|CDD\|235314	PRK04837, PRK04837, ATP-dependent RNA helicase RhlB; Provisional.	0
NC_019940.1\|WP_015280981.1\|2313012_2314113_+\|alkene-reductase	gnl\|CDD\|239243	cd02933, OYE_like_FMN, Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Members of OYE family include 12-oxophytodienoate reductase, pentaerythritol tetranitrate reductase, morphinone reductase, and related enzymes.	0
NC_019940.1\|WP_015280980.1\|2311912_2312863_+\|AEC-family-transporter	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	4.19201e-42
NC_019940.1\|WP_015280978.1\|2309115_2309700_+\|ADP-compounds-hydrolase-NudE	gnl\|CDD\|183303	PRK11762, nudE, adenosine nucleotide hydrolase NudE; Provisional.	2.64172e-93
NC_019940.1\|WP_157633727.1\|2298918_2299869_+\|pseudouridine-synthase	gnl\|CDD\|182659	PRK10700, PRK10700, 23S rRNA pseudouridine(2605) synthase RluB.	1.6418e-97
NC_019940.1\|WP_015280964.1\|2292752_2293565_+\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.21068e-91
NC_019940.1\|WP_015280967.1\|2295816_2296266_+\|hemerythrin-domain-containing-protein	gnl\|CDD\|376622	pfam01814, Hemerythrin, Hemerythrin HHE cation binding domain. Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor hemerythrin binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial NorA is a regulator of response to NO, which suggests yet another set-up for its metal ligands. In Staphylococcus aureus the iron-sulfur cluster repair protein ScdA has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger.	2.38961e-05
NC_019940.1\|WP_015280971.1\|2300151_2301561_+\|glutamate--tRNA-ligase	gnl\|CDD\|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
NC_019940.1\|WP_083884797.1\|2301576_2301747_+\|nucleotidyltransferase-substrate-binding-protein	gnl\|CDD\|378048	pfam08780, NTase_sub_bind, Nucleotidyltransferase substrate binding protein like. Nucleotidyltransferases (EC 2.7.7) comprise a large enzyme family with diverse roles in polynucleotide synthesis and modification. This domain is structurally related to kanamycin nucleotidyltransferase (KNTase) and forms a complex with HI0073, a sequence homolog of the nucleotide-binding domain of this nucleotidyltransferase superfamily.	4.50263e-08
NC_019940.1\|WP_015280972.1\|2301728_2301983_+\|nucleotidyltransferase-domain-containing-protein	gnl\|CDD\|376187	pfam18765, Polbeta, Polymerase beta, Nucleotidyltransferase. A member of the nucleotidyltransferase fold found in polymorphic toxins (NTox45) and polyvalent proteins.	1.4369e-06
NC_019940.1\|WP_041604340.1\|2296929_2297706_+\|nitroreductase-family-protein	gnl\|CDD\|236122	PRK07877, PRK07877, Rv1355c family protein.	0.0031404
NC_019940.1\|WP_015280979.1\|2310116_2311865_+\|chloride-channel-protein	gnl\|CDD\|238233	cd00400, Voltage_gated_ClC, CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This domain is found in the halogen ions (Cl-, Br- and I-) transport proteins of the ClC family. The ClC channels are found in all three kingdoms of life and perform a variety of functions including cellular excitability regulation, cell volume regulation, membrane potential stabilization, acidification of intracellular organelles, signal transduction, transepithelial transport in animals, and the extreme acid resistance response in eubacteria. They lack any structural or sequence similarity to other known ion channels and exhibit unique properties of ion permeation and gating. Unlike cation-selective ion channels, which form oligomers containing a single pore along the axis of symmetry, the ClC channels form two-pore homodimers with one pore per subunit without axial symmetry. Although lacking the typical voltage-sensor found in cation channels, all studied ClC channels are gated (opened and closed) by transmembrane voltage. The gating is conferred by the permeating ion itself, acting as the gating charge. In addition, eukaryotic and some prokaryotic ClC channels have two additional C-terminal CBS (cystathionine beta synthase) domains of putative regulatory function.	4.05013e-103
NC_019940.1\|WP_015280973.1\|2302493_2304179_+\|glutamine--tRNA-ligase/YqeY-domain-fusion-protein	gnl\|CDD\|235424	PRK05347, PRK05347, glutaminyl-tRNA synthetase; Provisional.	0
NC_019940.1\|WP_015280974.1\|2304486_2305743_-\|transcription-termination-factor-Rho	gnl\|CDD\|236490	PRK09376, rho, transcription termination factor Rho; Provisional.	0
NC_019940.1\|WP_015280975.1\|2305927_2306254_-\|thioredoxin-TrxA	gnl\|CDD\|181812	PRK09381, trxA, thioredoxin TrxA.	7.30695e-56
NC_019940.1\|WP_051022008.1\|2308032_2308668_-\|GMP/IMP-nucleotidase	gnl\|CDD\|237882	PRK14988, PRK14988, GMP/IMP nucleotidase; Provisional.	1.47841e-64
NC_019940.1\|WP_015280966.1\|2295028_2295586_+\|hypoxanthine-guanine-phosphoribosyltransferase	gnl\|CDD\|181675	PRK09162, PRK09162, hypoxanthine-guanine phosphoribosyltransferase; Provisional.	9.99827e-83

>NC_019940.1|WP_015280972.1|2301728_2301983_+|nucleotidyltransferase-domain-containing-protein
MASDELSFGLSRRIREDLNGAFARYSEVERVLLFGSRADGTSAHGSDIALAVLAPTMTSQRFSQLWGDIDALSILFETDITRPL
>NC_019940.1|WP_083884797.1|2301576_2301747_+|nucleotidyltransferase-substrate-binding-protein
MIQDGNGWTEIQRDRNLTSHTDDEHLADEVYAFIASRALDLLRALAEEAGQWRATN
>NC_019940.1|WP_015280971.1|2300151_2301561_+|glutamate--tRNA-ligase
MTVRTRFAPSPTGYLHVGGARTALFSYLHARKHGGQFVLRIEDTDLERSTAESVNAILEGMTWLGLDYDEGPFYQTQRFDRYNAVIEELLEKGLAYRCDCPKERLDELRDSQMAQRLKPRYDGRCRQREVDPSEPHVIRFRNPTDGVIVINDLIRGRVPFSNTELDDLIIRRSDGSPTYNLTVVVDDADMGITHVIRGDDHLNNTPRQVNILRALGHEPPSYAHVPMILGDDGARLSKRHGAVSVIAYREAGFLPEALLNYLVRLGWSHGDEEIFSLQEMIELFDIADVNRAASSFNTEKLAWLNQHYIQHGDPKRIAQLLRPHMGRIGIDPSEGPDLTAVVEAQAARAKTLVELAEISAFCYRDFDDYDAAAAKKHLRLAAREGLERLRAAFELMAYEDWTPQGLHHVVEHVAEELGVNLGKVAQPLRVAIVGRAASPGIDVTLHLVGKDATLRRIAKALAYIDQRGA
>NC_019940.1|WP_157633727.1|2298918_2299869_+|pseudouridine-synthase
MRKTPPPRRPRANTRPHRPGPSSPALPTEGVRLQKYLAELGLGSRRSIDGWIAEGRVRVNGRPAKLGERVTRADRIRVDGQEVAPRRQQIKAAAAGPQVIAYNKPEGEVVTRHDPEDRPTVFRRLPRPRYGRWIAVGRLDLNTSGLILFTNDGELANRLMHPSREIEREYAVRILGPVAPQALAQLTDGVTLEDGPARFETIAEAGGQGANRWYHVVLREGRNREVRRLWEAVGCQVSRLIRVRYGSVSLGARLFSGNWRPLSDAELDDLLALAGMAPVRPRRRRPPTFGTHQPTHPDKAPATRSEQRSRRPKRLP
>NC_019940.1|WP_157633726.1|2297741_2298821_+|FAD:protein-FMN-transferase
MVPCAPLSRLFARLPSHHAWRHPAWVTLLVVLGLGLASCGEPRDPMLEVSGPTMGTFYSVKVARPPAELTAHALQQTVDTVLDEVIAEISTYDPTSELSRLNVNPTTDWVPLSPDLLTVIDEGQRISHLSGGAFDITVGPLVNLWGFGPEHRPDAVPDPAAIAAARERVGYEKLSLRADPPAIRKTRGDIYIDLSALGEGYGAARVATALEARGVTDYMVAIAGAIRVRGRNPKGTPWVIAIEEPTPGRRSVHRIIEISDGALSTSGDYRNFFEEGGQRYSHEIDPKTGRPVAQSLASVTVIDDDATRADGLATALMVMGEDEGPALAEAQLIPAYFIIREDEGFRVVVTPSFQRYLRE
>NC_019940.1|WP_041604340.1|2296929_2297706_+|nitroreductase-family-protein
MVQAAAAQGFDAEPTYSSTVDGIVVQLERSAWAKANELYAAIPHRQCVRKPYDGQPLGRAELAKLTGIGRGSRAQTLILVTEAAKEAVTEFVTQGNALQLTDRAYRRELAAWMRFNNGEAMRRGDGRSARATGRLLPLPGLLARLMSKQIFDPESHSARDAKQIRRSAGVAVFVASEDDKSTWIDVGRACQRFALQATALDIRTAFINQPIHARALQSQFDEWLQLKGERAMLMLRFGHGPKAPFSLRRPVDEVIVKS
>NC_019940.1|WP_015280967.1|2295816_2296266_+|hemerythrin-domain-containing-protein
MQTLNGYRQSHAELRQMIDDLRAIMTKDQLKIRPNAKTAYELLCELGEKMKHHLAEEDRGLYPNLLIHEDPKVKSIAWGFISGEKPLRKTFDDYYKRWLKNCDFQFSDEFMAETNEVFDMVSGRIDREEHVLFPKLVEIGLFSETYNAA
>NC_019940.1|WP_015280966.1|2295028_2295586_+|hypoxanthine-guanine-phosphoribosyltransferase
MKLTDADSAAVAGRAECLVTGEEMERILDRLAAEVTETLHDKDPVVLCIMTGGIIAVGQLLPRLGFPLRLEYAHLTRYLGATSGGELEWRHRPSEAVRGEHVLIVDDILDEGITLRAIREACEADGAASIQSLVLVEKDRPRAVPCAADFVGVHLPNRYLYGYGLDYKHYFRNARGVYAVADEDT
>NC_019940.1|WP_015280965.1|2293956_2295042_+|beta-N-acetylhexosaminidase
MSLGPVMLDLDGPELSPEERELLGHPAVGGVILFSRNFVEPAQIAALTSAIHAVREPHLLIGVDQEGGRVQRFREGFTRLPPVGRIGALFRDHPARGLRAAERLGWLMAAELRAVGVDFSFAPVLDLDRGISHVIGDRAFGDSQTAVTELATAWMRGVHAAGMAAVGKHFPGHGGVAADSHAELPRDERPLEALRHADLIPFERLIGHGLEAIMPAHVVYPRIDPQPAGFSSFWLRTLLRRELDFQGIIFSDDLTMQGAAGVGDHRARADLALSAGCDMILVCNDRAAALETIDGRGPHEDPTICLRLLRMHGRQALDNTALHQDPRREEALHSLAELDRYALPSLDLEDPTSHGKQNETD
>NC_019940.1|WP_015280964.1|2292752_2293565_+|ABC-transporter-permease
MRPRWSVTLPVLVVGLWALAALSGPWLPLAPDRIDLPQILAPPSPEAWLGSDDLGRPVLDRLLVGARTAFLVGFGVVAVSALVGTLIGAVSGYVGGWVDLLLVRVIDVFLAFPGILLAIALAGILDPGLGNVVIALSVVGWVGYARLARAQILSLKQRDHVLAARALGAGHVRILTRHLLPLALAPLIVEATFGIAGAVIAEAGLSFLGLGVQPPAASWGSMIRDGVGYMLVAPHLVLAPGLAILLVVLAVNLLGDALRDHLDVRGPGRR
>NC_019940.1|WP_015280973.1|2302493_2304179_+|glutamine--tRNA-ligase/YqeY-domain-fusion-protein
MSEPAVTSKTNFIRQIIEEDLAAGRHTRIATRFPPEPNGYLHIGHAKSIVLNFGLAQDYPGICNLRFDDTNPHKENHEFVEAIKADVRWLGYDWGERVYFASDYFERLYAFAVELIEKGLAYVCDLTAEEIREHRGTLTVPGRDSPHRDRQVAENLDLFRRMRAGEFPDGSHTLRARIDMASPNINLRDPVLYRIRHGVIHHQTGSEWCLYPTYDYTHPISDALEGITHSLCTLEFEDHRPLYDWCIDHVSVPSKPRQIEFSRLNLEYTVMSKRRLTQLVEEGHVQGWDDPRLPTIAGLRRRGYTPAAIRTFCDRIGVTKSDNLVEMAMLESAIRDDLDATAPRRMAVLRPLKVVIDTLPADHDELLEAANHPKDPAQGSRQIPFTREIYIDREDFAEDPPKGFKRLVPGGEVRLRSGYVIRCEEVIRDETGALVALRASHDPATLGAKPEGRKVKGVIHWVPATEAVAAEVRLYDRLFQVPEPGAGGRDFRDDINPASLVVIDGALVEPALADCQPGERFQFEREGYFVVDPDSTTGRLCFNRTVGLRDSWGKAQGKQGG
>NC_019940.1|WP_015280974.1|2304486_2305743_-|transcription-termination-factor-Rho
MNLTELKKTAVPDLVELAQSMEIEGVGRSRKQDLIFAILKAQARRGEDIYGDGVLEILQDGFGFLRSADASYLAGPDDIYVSPSQIRRFALRTGDTISGKIRPPKDGERYFALLKVGDINYDRPENAKTKILFENFTPLFPQKRLKLEVGNGSTEDITARTIDLVAPIGMGQRGLIVSPPKAGKTMILQNIAQSIGHNYPDCYLIVLLIDERPEEVTEMARSVRGEVISSTFDEPATRHVQVAEMVIEKAKRLVEHKRDVVILLDSITRLARAYNTVVPSSGKVLTGGVDANALQRPKRFFGAARNVEEGGSLTILATALVDTGSRMDDVIYEEFKGTGNMELHLDRRIAEKRIFPAININRSGTRREELLMNPDELQKMWILRRILHPMDELAAMEFLHDKLKATKTNNEFFDSMRG
>NC_019940.1|WP_015280975.1|2305927_2306254_-|thioredoxin-TrxA
MSESIVHVTDDSFERDVLQSPEPVLVDYWADWCGPCKMIAPVLDEIATEYAGKVRVAKLNIDENPNTPPRYGIRGIPTLMLFKGGEVEATKVGAVSKSQLTAFIDSNL
>NC_019940.1|WP_015280976.1|2306461_2307931_+|ATP-dependent-RNA-helicase-RhlB
MTETHLTDTRFDSFDLDTRILKALDEAGFTHCTPIQAETLPIGLAGRDVAGQAQTGTGKTAAFLIVTLQRLLTNPRPDATEVKDPRVLILAPTRELAVQIHRDTLALAKHTDFRIGLVYGGTGYQQQRDDLARGVDILIGTPGRLIDYFKQKVFSLRHVEVAILDEADRMFDLGFIKDIRFLLRRMPPPEERLGLLFSATLSYRVTELAYEHMNNPELIKVEPDRVTAERVTQSGYMVANEEKIPLLIGLLRRLEGARAIVFANTKRETERIWGYLEGNGLRAAILSGDVPQRKRLSLLRHFTAGDLPILVATDVAARGLHIPDVTHVINYDLPEDAQDYVHRIGRTARAGAAGAAISFVCETYAFSLPDIEDFIGIKVPIDHIDPDLLAEVDPTSRVRTPRRERISRDERGKGRATPGGKQPRGRRDGPSDAPREEAAPAAPEAGQHDAATSPNDNAPSPKKRRRRRRRPTARPEDGQAVAPPPAEQP
>NC_019940.1|WP_051022008.1|2308032_2308668_-|GMP/IMP-nucleotidase
MDGTLLDLHFDNHFWLEHVPLRYSQARGIELAEAKELLYGKYRDREGTLEWYCVDHWSRDLGLDIALLKQEVEHLIAVHPHVLDFLVALAARGKRRVLVTNAHQRSIALKMQRTALAGQLDRLICAHDLAEPKESPDFWQRVQTIEPFDRARTLFVDDNERVLQTARDYGFRWLLAVLEPDSRRSARADSAFPAIRHFADLLPGLRAEENP
>NC_019940.1|WP_015280978.1|2309115_2309700_+|ADP-compounds-hydrolase-NudE
MAERPKVLSRRLAAESRLFRIEQLELEFANGARRTYERLLGGPDSVMVVALQDPQTVLLIREYAAGTERYELGLPKGVVEPGEDPLAAAHRELQEEVGFGARELQIIHRVSLVPGYIQHHTLVVLARDLYPNRAEGDEPEPIEVVPWRLDALDELLVQPDFGEARTIAGLFLAYRFLARERAAGQTPSPSPDEV
>NC_019940.1|WP_015280979.1|2310116_2311865_+|chloride-channel-protein
MSQHRSLAKWFRSELEWLRIRLAHPEALFWNVLLGLVTGLITGAVIVIFRLVVEGSQAAMLPGNGENYEALPVWLRLSLPLAGALLIALIFWRFAKGTYVLGVARVMERMEYHQGHFERRELVMQFLGAAIAIVSGHSVGREGPHVHLGAASGSLLGQFLKLPNNSIRIIVVCGTAAGIAASFNTPLAGVIFALEVLALEYRIAAFMPVMLAAVSADTVSFAAFGSAPAFQVPPFQLSSLDDLLPVAVLGLLAGVVSVIYIQSLQTVAELGHRLGFFWRLTVAGALAGLFGALAPEVMGIGYDTQATLLMQQAPWLFLVTLLVFKLLATSTSIGLGIPGGTIGPALFMGAILGNLVGGLAAAVGVIDASDTSFYALLGMAAMMGASLQAPLAALTAVLELSHTPAIIMPGMLAIILAALTSREVFGKDSMFVTMLRANGLDYRTNPVIEMLRRSGVGGVMNRDFVRHAPQVRRDEAEHLLGGDGPEWILVDQDDQPTYLMPGIAVATYLAQSPDEEEIDLLAIPAERLELAPVHLEATLKEALDILESRSAEALYVQRPVAPGINRIYGVLTRARIESAYRY
>NC_019940.1|WP_015280980.1|2311912_2312863_+|AEC-family-transporter
MNQFLVTLNFALSVTGPIVLVLVIGVFLARLGLLTGAFIDAGTRLVFNVTLPCLLFVTISQTRFEQTANLTLIAVGVFGTLALFLVAEAVAARLVDPPVDRGVVVQGIYRGNMAIIGLAYCVNAYGDVAIAAASLYIGLLSILYNVLAVITLSRSLDRRGSLRAVVTGIVMNPLIIGILTALPFAYFEVSLPDLLVQTGEYFAQMTLPLALLCIGGSLSLATLRLDSHNALIATLGKVLFAPTAMTCIALLAGLRGMELGILFMMSAAPTAASSYVMSRAMGGNGPLSANIVVLTTIGSVLFTSLGITLLHLGELM
>NC_019940.1|WP_015280981.1|2313012_2314113_+|alkene-reductase
MSTDTTSDLFRPYRLGKLELANRIVMAPLTRSRAGEGDVPTPLMATYYVQRATAGLIITEASQISPQGKGYIQTPGIYSAAQIAGWRAITDAVHARGTKIFIQLWHVGRISHPELQEGGALPVAPSAVKANGQVFTGRGMVDMVTPRALTLDEIPGLVADYRQAAANAKEAGFDGVEIHSANGYLLDQFLRDKTNRRTDAYGGSIENRARLLLEVTDAVLEIWDKPRVGVRLSPLSPANDIDDSDPEPLFTHVVTELGARGIGYLHVVEGVTGGPRETGHSFRLETLRGRFPGTYIANNGYTRELALTARAADSADLIAFGRPFIANPDLVERLQSDAPLNTPDQATFYGGDAHGYTDYPFLADGA
>NC_019940.1|WP_015280982.1|2314180_2315143_-|hypothetical-protein
MRERLAALEAACSRSDDDQIVEALRTALADRHYRLVARAAELAGDRLLYAVESELRGAYARFLDDPIKRDPGCTAKGAIARALVALDCQDADFYTAGLRYRQPEPVWGGTTDRAVDLRVTCAIGLAATAEPRALIHLVQLLHDPEPHARCGAVRAIGCTQPLAAEAVLRAKVLSGDEEPEVTGEAFAALLQLAEGDALDFVAGFLEAPEGEVAAMAALALGASHLDAALERLRARWAAEPLKDAASRVLLQAAALHRSVAALEWLTAVIAEADLDSAEVALTELARYRRGAQVQHRLAAALAARGDARLLARFAEIFPAS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	DI373489	KR 1020130142837-A/3: Bacteriophage of Pseudomonas aeruginosa and uses thereof	8953-8988	1	0.972
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	MN871456	UNVERIFIED: Pseudomonas phage Pa-C, complete genome	44976-45011	1	0.972
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	MH791406	UNVERIFIED: Pseudomonas phage PaSz-4, complete genome	14198-14233	1	0.972
NC_019940_4	4.19\|1384141\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384141-1384176	36	MN871456	UNVERIFIED: Pseudomonas phage Pa-C, complete genome	6531-6566	2	0.944
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	MN871482	UNVERIFIED: Pseudomonas virus PaSz-6, complete genome	48015-48050	2	0.944
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	MN871486	UNVERIFIED: Pseudomonas phage PaSz-9_45_61k, complete genome	31055-31090	2	0.944
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	MH791403	UNVERIFIED: Pseudomonas phage PaTs-2, complete genome	46189-46224	2	0.944
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	MN871463	UNVERIFIED: Pseudomonas phage Pa-L, complete genome	22116-22151	2	0.944
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	JX131330	Pseudomonas phage MP1412, complete genome	7258-7293	2	0.944
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	MN871469	UNVERIFIED: Pseudomonas phage Pa-S, complete genome	45969-46004	2	0.944
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	MN871478	UNVERIFIED: Pseudomonas phage PaSt-2_45_61k, complete genome	46189-46224	2	0.944
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	NC_010116	Pseudomonas phage YuA, complete genome	7257-7292	2	0.944
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	MT118302	Pseudomonas phage Epa38, complete genome	20183-20218	2	0.944
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	NC_028980	Pseudomonas phage PAE1, complete genome	33755-33790	2	0.944
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	MF490239	Pseudomonas phage vB_PaeS_S218, complete genome	15638-15673	2	0.944
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	DQ163916	Bacteriophage M6, complete genome	36284-36319	2	0.944
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	KX198613	Pseudomonas phage AN14, complete genome	31982-32017	2	0.944
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	KC758116	Pseudomonas phage LKO4, complete genome	7257-7292	2	0.944
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	NC_007809	Pseudomonas phage M6, complete genome	36284-36319	2	0.944
NC_019940_4	4.24\|1384504\|37\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384504-1384540	37	JQ067084	Pseudomonas phage PaMx25, complete genome	3269-3305	3	0.919
NC_019940_4	4.24\|1384504\|37\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384504-1384540	37	KX898399	Pseudomonas phage JG012, complete genome	1404-1440	3	0.919
NC_019940_4	4.24\|1384504\|37\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384504-1384540	37	NC_031058	Pseudomonas phage NP1, complete genome	3273-3309	3	0.919
NC_019940_4	4.19\|1384141\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384141-1384176	36	MN871486	UNVERIFIED: Pseudomonas phage PaSz-9_45_61k, complete genome	53203-53238	4	0.889
NC_019940_4	4.23\|1384431\|37\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384431-1384467	37	NC_023285	Streptomyces sp. F8 plasmid pFRL5, complete sequence	293682-293718	6	0.838
NC_019940_1	1.1\|349602\|34\|NC_019940\|PILER-CR,CRISPRCasFinder,CRT	349602-349635	34	NZ_CP050953	Rhodococcus sp. DMU1 plasmid unnamed	669066-669099	7	0.794
NC_019940_1	1.7\|350016\|32\|NC_019940\|PILER-CR,CRISPRCasFinder,CRT	350016-350047	32	KY499642	Vibrio phage pVa-21, complete genome	157381-157412	8	0.75
NC_019940_2	2.1\|355358\|34\|NC_019940\|PILER-CR,CRISPRCasFinder,CRT	355358-355391	34	MN692199	Pectobacterium phage MA12, complete genome	6268-6301	8	0.765
NC_019940_2	2.1\|355358\|34\|NC_019940\|PILER-CR,CRISPRCasFinder,CRT	355358-355391	34	MN518139	Pectobacterium phage MA11, partial genome	39718-39751	8	0.765
NC_019940_3	3.1\|356534\|33\|NC_019940\|CRISPRCasFinder	356534-356566	33	MK672805	Vibrio phage Va_PF430-3_p42, complete genome	4924-4956	8	0.758
NC_019940_4	4.50\|1386392\|35\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1386392-1386426	35	NZ_AP019824	Leptotrichia hofstadii strain JCM16775 plasmid pJCM16775-1, complete sequence	26228-26262	8	0.771
NC_019940_1	1.12\|350249\|32\|NC_019940\|PILER-CR	350249-350280	32	NC_011368	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence	897865-897896	9	0.719
NC_019940_2	2.9\|355918\|34\|NC_019940\|PILER-CR,CRISPRCasFinder,CRT	355918-355951	34	NZ_LT559121	Nonomuraea gerenzanensis isolate nono1 plasmid II, complete sequence	15490-15523	9	0.735
NC_019940_4	4.29\|1384868\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1384868-1384903	36	NZ_CP040819	Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence	476201-476236	9	0.75
NC_019940_4	4.58\|1386974\|36\|NC_019940\|CRISPRCasFinder,CRT,PILER-CR	1386974-1387009	36	CP036360	Agrobacterium sp. 33MFTa1.1 plasmid p_JBx_073812, complete sequence	137891-137926	9	0.75

1. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to DI373489 (KR 1020130142837-A/3: Bacteriophage of Pseudomonas aeruginosa and uses thereof) position: , mismatch: 1, identity: 0.972

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgaccacggtgcggtcgaagctgtagg	Protospacer
**********************************.*

2. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to MN871456 (UNVERIFIED: Pseudomonas phage Pa-C, complete genome) position: , mismatch: 1, identity: 0.972

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgaccacggtgcggtcgaagctgtagg	Protospacer
**********************************.*

3. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to MH791406 (UNVERIFIED: Pseudomonas phage PaSz-4, complete genome) position: , mismatch: 1, identity: 0.972

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgaccacggtgcggtcgaagctgtagg	Protospacer
**********************************.*

4. spacer 4.19|1384141|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to MN871456 (UNVERIFIED: Pseudomonas phage Pa-C, complete genome) position: , mismatch: 2, identity: 0.944

gctgggccgcgaccaaaccacagagtggccccggac	CRISPR spacer
gctgggccgcgaccaaaccacggaatggccccggac	Protospacer
*********************.**.***********

5. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to MN871482 (UNVERIFIED: Pseudomonas virus PaSz-6, complete genome) position: , mismatch: 2, identity: 0.944

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgatcacggtgcggtcgaagctgtagg	Protospacer
************.*********************.*

6. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to MN871486 (UNVERIFIED: Pseudomonas phage PaSz-9_45_61k, complete genome) position: , mismatch: 2, identity: 0.944

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgatcacggtgcggtcgaagctgtagg	Protospacer
************.*********************.*

7. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to MH791403 (UNVERIFIED: Pseudomonas phage PaTs-2, complete genome) position: , mismatch: 2, identity: 0.944

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgatcacggtgcggtcgaagctgtagg	Protospacer
************.*********************.*

8. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to MN871463 (UNVERIFIED: Pseudomonas phage Pa-L, complete genome) position: , mismatch: 2, identity: 0.944

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgatcacggtgcggtcgaagctgtagg	Protospacer
************.*********************.*

9. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to JX131330 (Pseudomonas phage MP1412, complete genome) position: , mismatch: 2, identity: 0.944

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgatcacggtgcggtcgaagctgtagg	Protospacer
************.*********************.*

10. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to MN871469 (UNVERIFIED: Pseudomonas phage Pa-S, complete genome) position: , mismatch: 2, identity: 0.944

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgatcacggtgcggtcgaagctgtagg	Protospacer
************.*********************.*

11. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to MN871478 (UNVERIFIED: Pseudomonas phage PaSt-2_45_61k, complete genome) position: , mismatch: 2, identity: 0.944

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgatcacggtgcggtcgaagctgtagg	Protospacer
************.*********************.*

12. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to NC_010116 (Pseudomonas phage YuA, complete genome) position: , mismatch: 2, identity: 0.944

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgatcacggtgcggtcgaagctgtagg	Protospacer
************.*********************.*

13. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to MT118302 (Pseudomonas phage Epa38, complete genome) position: , mismatch: 2, identity: 0.944

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgatcacggtgcggtcgaagctgtagg	Protospacer
************.*********************.*

14. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to NC_028980 (Pseudomonas phage PAE1, complete genome) position: , mismatch: 2, identity: 0.944

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgatcacggtgcggtcgaagctgtagg	Protospacer
************.*********************.*

15. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to MF490239 (Pseudomonas phage vB_PaeS_S218, complete genome) position: , mismatch: 2, identity: 0.944

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgatcacggtgcggtcgaagctgtagg	Protospacer
************.*********************.*

16. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to DQ163916 (Bacteriophage M6, complete genome) position: , mismatch: 2, identity: 0.944

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgatcacggtgcggtcgaagctgtagg	Protospacer
************.*********************.*

17. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to KX198613 (Pseudomonas phage AN14, complete genome) position: , mismatch: 2, identity: 0.944

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgatcacggtgcggtcgaagctgtagg	Protospacer
************.*********************.*

18. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to KC758116 (Pseudomonas phage LKO4, complete genome) position: , mismatch: 2, identity: 0.944

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgatcacggtgcggtcgaagctgtagg	Protospacer
************.*********************.*

19. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to NC_007809 (Pseudomonas phage M6, complete genome) position: , mismatch: 2, identity: 0.944

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
cgctgaactcgatcacggtgcggtcgaagctgtagg	Protospacer
************.*********************.*

20. spacer 4.24|1384504|37|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to JQ067084 (Pseudomonas phage PaMx25, complete genome) position: , mismatch: 3, identity: 0.919

gcgggggagaagcacgggcacaaatcggattacacgg	CRISPR spacer
gcgggtgagaagcacgggcacaaatccgattacactg	Protospacer
***** ******************** ******** *

21. spacer 4.24|1384504|37|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to KX898399 (Pseudomonas phage JG012, complete genome) position: , mismatch: 3, identity: 0.919

gcgggggagaagcacgggcacaaatcggattacacgg	CRISPR spacer
gcgggtgagaagcacgggcacaaatccgattacactg	Protospacer
***** ******************** ******** *

22. spacer 4.24|1384504|37|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to NC_031058 (Pseudomonas phage NP1, complete genome) position: , mismatch: 3, identity: 0.919

gcgggggagaagcacgggcacaaatcggattacacgg	CRISPR spacer
gcgggtgagaagcacgggcacaaatccgattacactg	Protospacer
***** ******************** ******** *

23. spacer 4.19|1384141|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to MN871486 (UNVERIFIED: Pseudomonas phage PaSz-9_45_61k, complete genome) position: , mismatch: 4, identity: 0.889

gctgggccgcgaccaaaccacagagtggccccggac	CRISPR spacer
gctgggccgcgaccagaccacggagtggccccgttc	Protospacer
***************.*****.***********  *

24. spacer 4.23|1384431|37|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to NC_023285 (Streptomyces sp. F8 plasmid pFRL5, complete sequence) position: , mismatch: 6, identity: 0.838

cccgctacgc-caccatccgcgccgcctggcgcgccgt	CRISPR spacer
-ccgcggcactcaccatccgcggcgcccggcgcgccgt	Protospacer
 **** .*.* *********** ****.**********

25. spacer 1.1|349602|34|NC_019940|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050953 (Rhodococcus sp. DMU1 plasmid unnamed) position: , mismatch: 7, identity: 0.794

gggcatcgaacgtccccttctcgcaccgcagggc-	CRISPR spacer
gggcatcgaacgtcacctgctcgc-cggcggcgta	Protospacer
************** *** ***** * **.* *.

26. spacer 1.7|350016|32|NC_019940|PILER-CR,CRISPRCasFinder,CRT matches to KY499642 (Vibrio phage pVa-21, complete genome) position: , mismatch: 8, identity: 0.75

ccgccaagaactccgatgaatatta-cgtaagg	CRISPR spacer
atcccaagaaattcgatgaatattaccgtcac-	Protospacer
 . ******* *.************ *** *

27. spacer 2.1|355358|34|NC_019940|PILER-CR,CRISPRCasFinder,CRT matches to MN692199 (Pectobacterium phage MA12, complete genome) position: , mismatch: 8, identity: 0.765

accggactcgtagccattaccgaacccggtatag	CRISPR spacer
gtcgaaaccgtagctattaccgtacccggtatcg	Protospacer
..**.* .******.******* ********* *

28. spacer 2.1|355358|34|NC_019940|PILER-CR,CRISPRCasFinder,CRT matches to MN518139 (Pectobacterium phage MA11, partial genome) position: , mismatch: 8, identity: 0.765

accggactcgtagccattaccgaacccggtatag	CRISPR spacer
gtcgaaaccgtagctattaccgtacccggtatcg	Protospacer
..**.* .******.******* ********* *

29. spacer 3.1|356534|33|NC_019940|CRISPRCasFinder matches to MK672805 (Vibrio phage Va_PF430-3_p42, complete genome) position: , mismatch: 8, identity: 0.758

ccgtcgatgagacgagctttggcaactttggcg	CRISPR spacer
agtttgatgagacgagcttcagcaactttgtca	Protospacer
   *.**************..********* *.

30. spacer 4.50|1386392|35|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP019824 (Leptotrichia hofstadii strain JCM16775 plasmid pJCM16775-1, complete sequence) position: , mismatch: 8, identity: 0.771

taaattgtctattttttcaatattcgtttcatcta	CRISPR spacer
aaatctcagtattttttccatattcttttcatcta	Protospacer
 ** .*   ********* ****** *********

31. spacer 1.12|350249|32|NC_019940|PILER-CR matches to NC_011368 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence) position: , mismatch: 9, identity: 0.719

tcagagcgaatgcgtttcgatcagggtctgga	CRISPR spacer
cgagagcgaatccgtttcgaccaggctgccgc	Protospacer
. ********* ********.**** * . *

32. spacer 2.9|355918|34|NC_019940|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT559121 (Nonomuraea gerenzanensis isolate nono1 plasmid II, complete sequence) position: , mismatch: 9, identity: 0.735

gatgtaggccagcggcgctgacca-ttgtccaata	CRISPR spacer
gatggaggccagaggcgctgaccagccgcctggt-	Protospacer
**** ******* *********** ..*.*...*

33. spacer 4.29|1384868|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040819 (Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence) position: , mismatch: 9, identity: 0.75

cgctgaactcgaccacggtgcggtcgaagctgtaag	CRISPR spacer
aggcgatctcgaccacggtgcgctcgaagcgggcgg	Protospacer
 * .** *************** ******* *  .*

34. spacer 4.58|1386974|36|NC_019940|CRISPRCasFinder,CRT,PILER-CR matches to CP036360 (Agrobacterium sp. 33MFTa1.1 plasmid p_JBx_073812, complete sequence) position: , mismatch: 9, identity: 0.75

--ggtcacgaccgcgcgggcgttggcgatgccgctgta	CRISPR spacer
ccggc--ggagcccgcgggcgttggcgatgccgcctga	Protospacer
  **.   ** * *********************.  *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

849046 : 878087

Pseudomonas_phage(33.33%)

transposase,plate,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015279765.1\|849046_850612_+\|tail	phage tail sheath family protein	S5VZH4	Pseudomonas_phage	2.3e-09	26.2
WP_015279766.1\|850622_851147_+\|tail	phage tail protein	NA	NA	NA	NA
WP_015279767.1\|851151_851850_+	hypothetical protein	NA	NA	NA	NA
WP_157633638.1\|852623_852794_+	hypothetical protein	NA	NA	NA	NA
WP_015279769.1\|852790_854101_+	DUF4255 domain-containing protein	NA	NA	NA	NA
WP_015279770.1\|854097_855984_+	ATP-binding protein	A0A2D2W2C3	Stenotrophomonas_phage	2.0e-07	30.2
WP_015279771.1\|855980_856235_+	hypothetical protein	NA	NA	NA	NA
WP_015279773.1\|858005_858665_+	hypothetical protein	NA	NA	NA	NA
WP_015279774.1\|858716_859079_+	hypothetical protein	NA	NA	NA	NA
WP_083884791.1\|859101_860211_+	hypothetical protein	NA	NA	NA	NA
WP_015279776.1\|860207_860729_+	hypothetical protein	J9PUM0	Bacillus_phage	3.3e-05	34.1
WP_015279777.1\|860731_861052_+	hypothetical protein	NA	NA	NA	NA
WP_015279778.1\|861160_861526_+	GPW/gp25 family protein	NA	NA	NA	NA
WP_015279779.1\|861522_864171_+\|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_041603390.1\|864167_866972_+\|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_015279781.1\|866968_869191_+	hypothetical protein	NA	NA	NA	NA
WP_015279782.1\|869243_871823_+	hypothetical protein	NA	NA	NA	NA
WP_015279783.1\|871832_872729_+	hypothetical protein	NA	NA	NA	NA
WP_015279784.1\|872794_873088_+	BrnT family toxin	NA	NA	NA	NA
WP_083884651.1\|873065_873290_+	BrnA antitoxin family protein	NA	NA	NA	NA
WP_157633639.1\|873568_874003_+	hypothetical protein	NA	NA	NA	NA
WP_157633640.1\|873999_874365_+	hypothetical protein	NA	NA	NA	NA
WP_015279787.1\|874459_874933_+	toll/interleukin-1 receptor domain-containing protein	NA	NA	NA	NA
WP_015279788.1\|874942_875791_+\|transposase	transposase	NA	NA	NA	NA
WP_157633641.1\|875717_876668_+	hypothetical protein	NA	NA	NA	NA
WP_086014990.1\|876955_878087_+\|transposase	IS3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

2242729 : 2282521

Burkholderia_phage(20.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015280925.1\|2242729_2243689_-\|transposase	IS5 family transposase	E5E3P6	Burkholderia_phage	6.8e-89	56.6
WP_157633720.1\|2243905_2245390_-	aminotransferase class V-fold PLP-dependent enzyme	NA	NA	NA	NA
WP_157633721.1\|2245867_2246695_-	hypothetical protein	NA	NA	NA	NA
WP_015280928.1\|2247298_2248726_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_015280929.1\|2248851_2249622_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_086014994.1\|2249764_2250996_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.6e-125	79.2
WP_157633722.1\|2251065_2251611_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.7e-47	51.2
WP_051021901.1\|2252185_2252494_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_015280931.1\|2252964_2253753_-\|transposase	ISAzo13 family transposase	NA	NA	NA	NA
WP_015280932.1\|2254447_2254720_-	oxidative damage protection protein	NA	NA	NA	NA
WP_015280933.1\|2254716_2255832_-	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_015280934.1\|2255831_2258111_-	AsmA family protein	NA	NA	NA	NA
WP_015280935.1\|2258377_2260198_-	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	6.7e-45	24.0
WP_015280936.1\|2260760_2260961_+	sulfur carrier protein ThiS	NA	NA	NA	NA
WP_015280937.1\|2261039_2261837_+	thiazole synthase	NA	NA	NA	NA
WP_083884796.1\|2261833_2262586_+\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_015280939.1\|2262585_2263206_+	ATP-binding cassette domain-containing protein	NA	NA	NA	NA
WP_015280940.1\|2263202_2263997_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_015280941.1\|2264072_2265062_+	serine/threonine protein kinase	NA	NA	NA	NA
WP_041603661.1\|2265274_2265463_+	hemin uptake protein HemP	NA	NA	NA	NA
WP_157633723.1\|2265521_2265836_+	hypothetical protein	NA	NA	NA	NA
WP_015280943.1\|2265848_2266334_-	bacterioferritin	NA	NA	NA	NA
WP_015280944.1\|2266377_2266842_-	bacterioferritin	NA	NA	NA	NA
WP_015280945.1\|2267144_2267354_+	(2Fe-2S)-binding protein	NA	NA	NA	NA
WP_015280947.1\|2267613_2267901_+	hypothetical protein	NA	NA	NA	NA
WP_157633724.1\|2268037_2269300_+	DUF2325 domain-containing protein	NA	NA	NA	NA
WP_051021903.1\|2269385_2273504_-	EAL domain-containing protein	A0A127AWB9	Bacillus_phage	1.3e-16	34.3
WP_015280950.1\|2274006_2275068_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_015280951.1\|2275060_2278294_+	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_051022005.1\|2278296_2279736_-	cardiolipin synthase	NA	NA	NA	NA
WP_015280953.1\|2279999_2281397_+	Si-specific NAD(P)(+) transhydrogenase	NA	NA	NA	NA
WP_172637464.1\|2281493_2281862_+	hypothetical protein	NA	NA	NA	NA
WP_041603665.1\|2281792_2282521_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_3

2820045 : 2886742

Paramecium_bursaria_Chlorella_virus(22.22%)

transposase,protease,integrase

attL 2830612:2830636|attR 2850690:2850714

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015281405.1\|2820045_2821968_-\|protease	ATP-dependent zinc metalloprotease FtsH	A0A0P0BXI2	Ostreococcus_lucimarinus_virus	3.7e-118	42.9
WP_041604455.1\|2822093_2822711_-	23S rRNA (uridine(2552)-2'-O)-methyltransferase RlmE	NA	NA	NA	NA
WP_015281407.1\|2822867_2823827_+	glutathione synthase	NA	NA	NA	NA
WP_015281408.1\|2823810_2824896_+	FAD:protein FMN transferase	NA	NA	NA	NA
WP_041603746.1\|2824952_2825819_+	energy transducer TonB	NA	NA	NA	NA
WP_015281410.1\|2825912_2826476_+	YqgE/AlgH family protein	NA	NA	NA	NA
WP_015281411.1\|2826476_2826878_+	Holliday junction resolvase RuvX	NA	NA	NA	NA
WP_015281412.1\|2826864_2827416_+	bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR	NA	NA	NA	NA
WP_015281413.1\|2827436_2828423_+	aspartate carbamoyltransferase catalytic subunit	A7RB08	Paramecium_bursaria_Chlorella_virus	5.5e-33	34.7
WP_015281414.1\|2828415_2829720_+	dihydroorotase	NA	NA	NA	NA
WP_015281415.1\|2829716_2830604_+	dihydroorotate dehydrogenase electron transfer subunit	NA	NA	NA	NA
2830612:2830636	attL	NA	NA	NA	NA
WP_015281416.1\|2830641_2831412_-	DnaJ domain-containing protein	NA	NA	NA	NA
WP_015281417.1\|2831416_2832127_-	hypothetical protein	NA	NA	NA	NA
WP_015281418.1\|2832237_2833764_-	hypothetical protein	NA	NA	NA	NA
WP_015281419.1\|2833772_2834552_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_015281420.1\|2834849_2836742_+	biosynthetic arginine decarboxylase	NA	NA	NA	NA
WP_015281421.1\|2836831_2837185_+	hydrogenase maturation nickel metallochaperone HypA	NA	NA	NA	NA
WP_015281422.1\|2837395_2838280_+	hydrogenase nickel incorporation protein HypB	NA	NA	NA	NA
WP_015281423.1\|2838406_2838937_+	hypothetical protein	NA	NA	NA	NA
WP_015281424.1\|2839037_2839637_-	HdeD family acid-resistance protein	NA	NA	NA	NA
WP_015281425.1\|2839732_2839960_-	hypothetical protein	NA	NA	NA	NA
WP_015281426.1\|2840077_2840320_-	BolA/IbaG family iron-sulfur metabolism protein	NA	NA	NA	NA
WP_051022024.1\|2840645_2841671_+\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	1.8e-63	44.1
WP_015281428.1\|2841689_2842064_+	hypothetical protein	NA	NA	NA	NA
WP_157633757.1\|2842267_2842621_+	hypothetical protein	NA	NA	NA	NA
WP_015281429.1\|2842779_2843217_+	PH domain-containing protein	A0A075E0D8	Dickeya_phage	1.7e-10	33.6
WP_015281430.1\|2843659_2844376_+	hypothetical protein	NA	NA	NA	NA
WP_015281431.1\|2844387_2845227_+\|transposase	transposase	NA	NA	NA	NA
WP_083884732.1\|2845338_2845632_+	hypothetical protein	NA	NA	NA	NA
WP_015281433.1\|2845609_2845816_+	type II toxin-antitoxin system HicB family antitoxin	NA	NA	NA	NA
WP_086014998.1\|2845812_2846043_+	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_015281435.1\|2846303_2846519_+	hypothetical protein	NA	NA	NA	NA
WP_041603747.1\|2846618_2848199_-	peptide chain release factor 3	A0A2K9L6L3	Tupanvirus	3.6e-10	32.8
WP_015281437.1\|2848474_2850184_-	gamma-glutamyltransferase	NA	NA	NA	NA
WP_015281438.1\|2850521_2850725_+	hypothetical protein	NA	NA	NA	NA
2850690:2850714	attR	NA	NA	NA	NA
WP_015281439.1\|2851192_2853103_+	ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	3.6e-49	27.8
WP_015281440.1\|2853248_2855837_+	mechanosensitive ion channel	NA	NA	NA	NA
WP_157633864.1\|2856028_2858851_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	9.7e-301	55.0
WP_015281442.1\|2858986_2860537_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_015281443.1\|2860553_2861081_-	hypothetical protein	NA	NA	NA	NA
WP_083884735.1\|2861067_2861523_-	cytochrome c	NA	NA	NA	NA
WP_015281445.1\|2861506_2862253_-	cytochrome c	NA	NA	NA	NA
WP_015281446.1\|2862348_2863800_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_051021918.1\|2864165_2865092_+	transporter	NA	NA	NA	NA
WP_015281448.1\|2865340_2866387_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015281449.1\|2866424_2869109_-	DNA polymerase I	S5M8J1	Bacillus_phage	5.1e-65	27.9
WP_041603749.1\|2869230_2869881_-	response regulator transcription factor	NA	NA	NA	NA
WP_041603750.1\|2870645_2872115_+	PAS domain S-box protein	NA	NA	NA	NA
WP_015281453.1\|2872298_2873684_+	hypothetical protein	NA	NA	NA	NA
WP_015281454.1\|2873747_2874857_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_015281455.1\|2875054_2875522_+	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_015281456.1\|2875496_2876132_+	septum formation inhibitor Maf	NA	NA	NA	NA
WP_015281457.1\|2876395_2877850_+	ribonuclease G	NA	NA	NA	NA
WP_015281458.1\|2877849_2881845_+	TIGR02099 family protein	NA	NA	NA	NA
WP_015281459.1\|2882320_2882527_+	hypothetical protein	NA	NA	NA	NA
WP_015281460.1\|2882883_2883714_+	carbon-nitrogen hydrolase family protein	M1HHT1	Paramecium_bursaria_Chlorella_virus	2.6e-12	24.3
WP_015281461.1\|2883857_2885300_+\|protease	metalloprotease TldD	NA	NA	NA	NA
WP_015281462.1\|2885392_2886742_+\|protease	metalloprotease PmbA	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_019941

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_019940

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection