CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_020526	Streptococcus suis SC070731, complete sequence	2 crisprs	PrimPol,DinG,WYL,csa3,cas3,DEDDh	0	0	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_020526_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_020526_1

1772608-1772752

Orphan

Consensus_repeat	Method
GTCCACTCTCGCCGTTGCGCCTTTCCAGTTTCTTGGGCGCAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_020526_1

>merge|NC_020526|1|1772608-1772752|CRISPRCasFinder
GTCCACTCTCGCCGTTGCGCCTTTCCAGTTTCTTGGGCGCAAGCTAAAAAGACCCGTCGGGGTCTCAATTCGCTTTCTTATTTTCATGCTCATGAAAAAACAGTCCATTCTCGCCGTTGCGCCTTTCCAGTTTCTTGGGCGCAAG

>NC_020526|1|1|1772608-1772752|CRISPRCasFinder
GTCCACTCTCGCCGTTGCGCCTTTCCAGTTTCTTGGGCGCAAG	CTAAAAAGACCCGTCGGGGTCTCAATTCGCTTTCTTATTTTCATGCTCATGAAAAAACA
GTCCATTCTCGCCGTTGCGCCTTTCCAGTTTCTTGGGCGCAAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_020526.1\|WP_002942409.1\|1773050_1773545_-\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|180915
NC_020526.1\|WP_012027724.1\|1763788_1764754_+\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380514
NC_020526.1\|WP_012775325.1\|1782974_1783943_-\|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha	unknown	unknown	gnl\|CDD\|238958
NC_020526.1\|WP_012027737.1\|1775568_1776558_-\|lipoate--protein-ligase	unknown	unknown	gnl\|CDD\|161920
NC_020526.1\|WP_012027735.1\|1771732_1772389_+\|DUF1129-domain-containing-protein	unknown	unknown	gnl\|CDD\|368981
NC_020526.1\|WP_012775324.1\|1766283_1767345_-\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|223085
NC_020526.1\|WP_012027739.1\|1777929_1779690_-\|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl\|CDD\|273568
NC_020526.1\|WP_011922710.1\|1774086_1775250_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NC_020526.1\|WP_012775322.1\|1762353_1763808_+\|sucrose-6-phosphate-hydrolase	unknown	unknown	gnl\|CDD\|273554
NC_020526.1\|WP_002937767.1\|1779963_1781352_-\|dihydrolipoamide-acetyltransferase	unknown	unknown	gnl\|CDD\|237001
NC_020526.1\|WP_002939250.1\|1772778_1773018_-\|30S-ribosomal-protein-S18	unknown	unknown	gnl\|CDD\|178997
NC_020526.1\|WP_012775323.1\|1765662_1766220_-\|elongation-factor-P	unknown	unknown	gnl\|CDD\|234788
NC_020526.1\|WP_002942403.1\|1773556_1773847_-\|30S-ribosomal-protein-S6	unknown	unknown	gnl\|CDD\|179034
NC_020526.1\|WP_012027738.1\|1776687_1777878_+\|hypothetical-protein	unknown	unknown	unknown
NC_020526.1\|WP_012027722.1\|1760270_1762148_-\|PTS-sugar-transporter-subunit-IIBCA	unknown	unknown	gnl\|CDD\|131051
NC_020526.1\|WP_002942393.1\|1781692_1782688_-\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NC_020526.1\|WP_002942446.1\|1765242_1765635_-\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|377129
NC_020526.1\|WP_002938276.1\|1764833_1765253_-\|transcription-antitermination-factor-NusB	unknown	unknown	gnl\|CDD\|234686
NC_020526.1\|WP_012027732.1\|1767443_1770269_-\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NC_020526.1\|WP_002939248.1\|1770772_1771717_+\|magnesium-transporter-CorA-family-protein	unknown	unknown	gnl\|CDD\|213361

Protein	Function_ID	Function_description	E-value
NC_020526.1\|WP_002942409.1\|1773050_1773545_-\|single-stranded-DNA-binding-protein	gnl\|CDD\|180915	PRK07275, PRK07275, single-stranded DNA-binding protein; Provisional.	1.03536e-102
NC_020526.1\|WP_012027724.1\|1763788_1764754_+\|LacI-family-transcriptional-regulator	gnl\|CDD\|380514	cd06291, PBP1_Qymf-like, ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs. This group includes the ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus metalliredigens (strain Qymf) and its close homologs. Qymf is a strict anaerobe that could be grown in the presence of borax and its cells are straight rods that produce endospores. This group is a member of the LacI-GalR family repressors that are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	1.99878e-103
NC_020526.1\|WP_012775325.1\|1782974_1783943_-\|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha	gnl\|CDD\|238958	cd02000, TPP_E1_PDC_ADC_BCADC, Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain alpha-keto acid dehydrogenase/2-oxoisovalerate dehydrogenase complex (BCADC). PDC catalyzes the irreversible oxidative decarboxylation of pyruvate to produce acetyl-CoA in the bridging step between glycolysis and the citric acid cycle. ADC participates in the breakdown of acetoin while BCADC participates in the breakdown of branched chain amino acids. BCADC catalyzes the oxidative decarboxylation of 4-methyl-2-oxopentanoate, 3-methyl-2-oxopentanoate and 3-methyl-2-oxobutanoate (branched chain 2-oxo acids derived from the transamination of leucine, valine and isoleucine).	7.20442e-147
NC_020526.1\|WP_012027737.1\|1775568_1776558_-\|lipoate--protein-ligase	gnl\|CDD\|161920	TIGR00545, Probable_lipoate-protein_ligase_A, lipoyltransferase and lipoate-protein ligase. One member of this group of proteins is bovine lipoyltransferase, which transfers the lipoyl group from lipoyl-AMP to the specific Lys of lipoate-dependent enzymes. However, it does not first activate lipoic acid with ATP to create lipoyl-AMP and pyrophosphate. Another member of this group, lipoate-protein ligase A from E. coli, catalyzes both the activation and the transfer of lipoate. Homology between the two is full-length, except for the bovine mitochondrial targeting signal, but is strongest toward the N-terminus. [Protein fate, Protein modification and repair].	1.69881e-103
NC_020526.1\|WP_012027735.1\|1771732_1772389_+\|DUF1129-domain-containing-protein	gnl\|CDD\|368981	pfam06570, DUF1129, Protein of unknown function (DUF1129). This family consists of several hypothetical bacterial proteins of unknown function.	2.99466e-85
NC_020526.1\|WP_012775324.1\|1766283_1767345_-\|aminopeptidase-P-family-protein	gnl\|CDD\|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	5.90797e-112
NC_020526.1\|WP_012027739.1\|1777929_1779690_-\|dihydrolipoyl-dehydrogenase	gnl\|CDD\|273568	TIGR01350, Dihydrolipoyl_dehydrogenase, dihydrolipoamide dehydrogenase. This model describes dihydrolipoamide dehydrogenase, a flavoprotein that acts in a number of ways. It is the E3 component of dehydrogenase complexes for pyruvate, 2-oxoglutarate, 2-oxoisovalerate, and acetoin. It can also serve as the L protein of the glycine cleavage system. This family includes a few members known to have distinct functions (ferric leghemoglobin reductase and NADH:ferredoxin oxidoreductase) but that may be predicted by homology to act as dihydrolipoamide dehydrogenase as well. The motif GGXCXXXGCXP near the N-terminus contains a redox-active disulfide.	0
NC_020526.1\|WP_011922710.1\|1774086_1775250_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	1.6445e-28
NC_020526.1\|WP_012775322.1\|1762353_1763808_+\|sucrose-6-phosphate-hydrolase	gnl\|CDD\|273554	TIGR01322, Sucrose-6-phosphate_hydrolase, sucrose-6-phosphate hydrolase. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NC_020526.1\|WP_002937767.1\|1779963_1781352_-\|dihydrolipoamide-acetyltransferase	gnl\|CDD\|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	5.84394e-162
NC_020526.1\|WP_002939250.1\|1772778_1773018_-\|30S-ribosomal-protein-S18	gnl\|CDD\|178997	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed.	6.68341e-38
NC_020526.1\|WP_012775323.1\|1765662_1766220_-\|elongation-factor-P	gnl\|CDD\|234788	PRK00529, PRK00529, elongation factor P; Validated.	1.37279e-91
NC_020526.1\|WP_002942403.1\|1773556_1773847_-\|30S-ribosomal-protein-S6	gnl\|CDD\|179034	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed.	1.41522e-37
NC_020526.1\|WP_012027722.1\|1760270_1762148_-\|PTS-sugar-transporter-subunit-IIBCA	gnl\|CDD\|131051	TIGR01996, Includes:_Phosphotransferase_enzyme_IIB_component, PTS system, sucrose-specific IIBC component. This model represents the fused enzyme II B and C components of the sucrose-specific PTS sugar transporter system. Sucrose is converted to sucrose-6-phosphate in the process of translocation into the cell. Some of these transporters lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). The exceptions to this rule are Staphylococci, Streptococci, Lactococci, Lactobacilli, etc. which contain their own A domain as a C-terminal fusion. This family is closely related to the trehalose transporting PTS IIBC enzymes and the B and C domains of each are described by subfamily-domain level TIGRFAMs models (TIGR00826 and TIGR00852, respectively).	0
NC_020526.1\|WP_002942393.1\|1781692_1782688_-\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	1.50604e-179
NC_020526.1\|WP_002942446.1\|1765242_1765635_-\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|377129	pfam03780, Asp23, Asp23 family, cell envelope-related function. The alkaline shock protein Asp23 was identified as an alkaline shock protein that was expressed in a sigmaB-dependent manner in Staphylococcus aureus. Following an alkaline shock Asp23 accumulates in the soluble protein fraction of the S. aureus cell. Asp23 is one of the most abundant proteins in the cytosolic protein fraction of stationary S. aureus cells, with a copy-number of >25000 per cell. A second Asp23-family protein, AmaP, which is encoded within the asp23-operon, is required to localize Asp23 to the cell membrane. The overall function for the family is thus a cell envelope-related one in Gram-positive bacteria.	1.25433e-34
NC_020526.1\|WP_002938276.1\|1764833_1765253_-\|transcription-antitermination-factor-NusB	gnl\|CDD\|234686	PRK00202, nusB, transcription antitermination factor NusB.	6.30967e-49
NC_020526.1\|WP_012027732.1\|1767443_1770269_-\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NC_020526.1\|WP_002939248.1\|1770772_1771717_+\|magnesium-transporter-CorA-family-protein	gnl\|CDD\|213361	cd12827, EcCorA_ZntB-like_u2, uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family. A uncharacterized subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB (EcCorA-ZntB_like) family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes.The EcCorA-ZntB-like family includes the Mg2+ transporters Escherichia coli and Salmonella typhimurium CorAs, which can also transport Co2+, and Ni2+. Structures of the intracellular domain of EcCorA-ZntB-like family members, Vibrio parahaemolyticus and Salmonella typhimurium ZntB, form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA. Natural variants such as GVN and GIN, such as occur in some ZntB family proteins, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.	1.46201e-115

>NC_020526.1|WP_012027735.1|1771732_1772389_+|DUF1129-domain-containing-protein
MSFTEINGLTKKNQEFIHIATNQLIKDGKSDSEIKELLEEILPTIIEKQKTGVTARNLYGAPSEWAASKTISEQEKKDQVEYNENPWLMWLDSSLFMLAIIAGINGLMNLFGQGAQYGLLTLFVIGFGVGAGMYLMYHFVYREQIKTGQRPKLLKAIAFLGLATLAWSVVFILAALIPAAFNPVLPPLVTILIGAAAFGARYLLKKKYNIRNAMSPVQ
>NC_020526.1|WP_002939248.1|1770772_1771717_+|magnesium-transporter-CorA-family-protein
MKQIFLSTMTDLEEIQTFEPGAWINLVNPSQSESMEVAEHYKIDIADLRAPLDAEESSRITVEDDYTLILVDVPILEERNNKTYYITIPLGIILTDDAIITTCLEPLPLFEQFIHRRLRNFFTFMKSRFVFQILYRNAQLYLSALRTIDRKSEEIEKQLHEATRNEELIVLMELEKTIVYFKASLKTNERLVKKLASSSRLLRKYEEDEDLLEDTLVETQQAIEMADIYGSILNSMTHAFASIISNNQNTIMKTLALVTIVLSIPTMVFSAYGMNFKDNIIPFNDIPYAFWWIILFAFAISLSLTFYFIRKRWF
>NC_020526.1|WP_012027732.1|1767443_1770269_-|excinuclease-ABC-subunit-UvrA
MQENIVIHGARAHNLKNIDVTIPREKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGNMDKPDVDSIEGLSPAISIDQKTTSRNPRSTVGTATEINDYLRLLYARVGVPYCINGHGAIAASSVEQIVDEVLELPERQRLQILAPIVRKKKGQHKTIFEKIQKDGYVRVRVNGGVYDVSEVPELSKSKAHNIEVVVDRIVIKDGIRSRLFDSIEAALRIADGYVIIDTMDEKEMLFSEYYACPVCGFTVPELEPRLFSFNAPFGSCSDCDGLGMKLEVDTDLIVPDASKTLREGALAPWNPISSNYYPQMLEQAMNHFGVDMDKPFEELTEEEKNLIFNGSDGKEFHFHYENEFGGVRDIDIPFEGLITNINRRYRETNSDYTRTVMKTYMNELTCGTCHGYRLNDQALSVKVGGEQGLHIGQLSDLSVADHLQVIEHLTLSENEATIATPIVKEIKDRLSFLNNVGLNYLTLSRAAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADWLIDIGPGAGVFGGEIVASGTPAQVAKNKKSITGQYLSGKREIPVPLERRVGNGRFLEVTGAKENNLQDVTVRFPLGKFVAVTGVSGSGKSTLVNSILKKAIAQKLNRNSDKPGKFKSISGIEHLDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVFVPCEVCHGHRYNSETLEVHYKEKNIAQVLDMTVNDAVEFFKHIPKIERKLRTIQDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTEDIAQLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDMGPEGGVGGGTVVATGTPEEVAENPASFTGQYLKMKLK
>NC_020526.1|WP_012775324.1|1766283_1767345_-|aminopeptidase-P-family-protein
MQKRLEKFEAKLAQSTVDGILVTGQNNIYYLTGFWGTEATVFISGKRRLFVTDSRYTLIAKASVKGFDIIESRFALEEIAKVIKEDGLEKIGFDSEVTYGFYQSLTSIFEGYQLVAMSNFIEDLRMIKDEKEIATIRRACQISDQAFIDVLDFIKPGQTTEMDVNHFLDHRMRQLGAEGASFEFIVASGYRSAMPHGRASEKVIQSGETLTLDFGCYYQHYVSDMTRTIHIGHVTDQEREIYDVVLRANKALIEQAKEGVTYREFDAIPREIISAAGYGANFTHGIGHGIGLDIHEYPYFGKSDETIKAGMVLTDEPGIYLDDKYGVRIEDDLLITENGCEVLTLAPKELIVI
>NC_020526.1|WP_012775323.1|1765662_1766220_-|elongation-factor-P
MIEASKLRAGMTFEAEGKLIKVLDASHHKPGKGNTIMRMKLRDVRTGSTFDTTYRPDEKFEQAIIETVPAQYLYQMDDTAYFMNTETYDQYEIPVATIKEELLYILENSEVKIQFYGTEVIGVTVPTTVELVVAETQPSIKGATVTGSGKPATMETGLVVNVPDFIEAGQKLVINTAEGTYVSRA
>NC_020526.1|WP_002942446.1|1765242_1765635_-|Asp23/Gls24-family-envelope-stress-response-protein
MTTEYQGEIVIAPRVLEVITGIAAAKVDGVHSLQNKRVADSWSKTSLNKGVYLETDEEGRVTADIYVYLEYGVNVPAVSMDIQRAVKTAVYNYAEVQVAAVNIHVSGIVPDKTPKPALKDLFGEDFLDEE
>NC_020526.1|WP_002938276.1|1764833_1765253_-|transcription-antitermination-factor-NusB
MKNNRHALRKCALQAIVSLEFGQEPVQAAQFSYLYDREEEQEGVEIPLFLLNLVNGVADYRDDLDKELSSRLKAGWTLDRLTLIDKNIMRLGLFEILHFEETPDRVAVNEAIELAKEFSDESSAKFVNGVLSQFIKEEA
>NC_020526.1|WP_012027724.1|1763788_1764754_+|LacI-family-transcriptional-regulator
MVAKLTDVAQLAGVSPTTVSRVINKKGYLSEKTIRNVEEAMRELGYKPNNLARSLQGKSAKLVGLIFPTINNIFYSELISHLEKELFDRGYKTIICNSQHESDKEREYLEMLAANQVDGIISGSHNLGIQDYDRVVAPIIAFDRNLSPSIPIVSSDNFAGGVLAAQTLQKAGCHNPLMITGNDDSNSPTGLRQVGFTSILNKAEVFHISSDFSPVRKEMEIRAILEKQKPNGIFVSGDATAMLVWNVIRSMKLSIPEDIKLIGYDGTSFIENYYPQLTTIKQPLTEIARLLVELLVDKIEGKKLTKTDYILPISLLAGASI
>NC_020526.1|WP_012775322.1|1762353_1763808_+|sucrose-6-phosphate-hydrolase
MAFTTGERYRAYADWTPEYIEKIKKNTESSPWRTNFHIETPHGLLNDPNGFSYFNGKWTLFYQYFPFGAAHGLKSWVHTESTDLVHFEETGTVMYPDTPLDSHGAYSGSAMEFGDKLFLFYTGNVRDENWVRHPYQIGALMDKDGKIEKIDKVLIEQPEDTTDHFRDPQIFNYKGQYYAIVGGQNLDKKGIVKLYKAENNDYLNWSYVGDLDFANDMTAYMMECPNIAFVGEQPILLYCPQGLDKEVLDYGNIYPNMYKIGQSFVPETASIVEPSELINLDYGFECYATQAFNAPDGRTLSVSWLALPDVEYPTDAYDYQGCLSLVKELTIKDGKLYQYPVDAITSLRKEAQPFSAQKETNNVYELELDFSASTKHEIVLFANEAEKGLVLSVDTEQGQITLDRGNCGQPFALDFGTSRSCEISPGALTANIFIDKSVFEIFINKGEKVFSGRVFPDADQSGIVITTGNPTGTYYHLDYGRKTN
>NC_020526.1|WP_012027722.1|1760270_1762148_-|PTS-sugar-transporter-subunit-IIBCA
MNNTEIAKKVIDALGGRENVRSVAHCATRLRVMVVDEGKIDKDTVEDIEKVQGAFFNSGQYQIIFGTGTVNKIYDEVVALGLPTATTGEQKAEAAKQGNAFQRAIRTFGDVFVPIIPAIVATGLFMGLRGLLGALGYTLPEDLNVYSQILTDTAFIVLPALVVWSTFRVFGGNQTIGIVLGMMLIAGQLPNAWVVASGGDVKPTIFFGFIPVVGLQGSVLPAFIIGLVGAKFEKAVRKVVPEVLDLLVTPFVTLFVMSILGLFVIGPVFHVVENYILAGTQAILNLPMGLGGLLIGGVHQVIVVSGVHHIFNFLEAQLVANTGANPFNAIITAAMTAQGAATVAVGVKTKNPKLKALAFPAALSAFLGITEPAIFGVNLRFRKPFLLSLIAGAIGGAVASLLGLAGKGMGVTIIPGATLYVGNGQLFQYILMVAVSFALGFALTYLFGFEDEVEAAPKAAAAPVATPATPAVELNEETLVSPLSGDVVALENVNDPVFSSGAMGKGLAVKPSEGVVYAPADAEVTIAFETGHAYGLKTASGAELLIHIGIDTVSMNGNGFEKLVAAGDKVKAGTPLAKFDAAKIAEAGLDDTTMIIVTNTADFAEVSPLAEGTIAHGVEFLKVAK
>NC_020526.1|WP_002939250.1|1772778_1773018_-|30S-ribosomal-protein-S18
MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFISERGKILPRRVTGTSAKNQRKVTTAIKRARVMALLPFVNED
>NC_020526.1|WP_002942409.1|1773050_1773545_-|single-stranded-DNA-binding-protein
MINNVVLVGRMTRDAELRYTPSNQAVATFTLAVNRNFKNQNGEREADFINVVIWRQQAENLANWAKKGALIGVTGRIQTRSYDNQQGQRVYVTEVVAESFQLLESRTAREGQGGGYSAGNSFAGGNDYNSPYQAPAQSTPNFAREESPFGASNPMDISDDDLPF
>NC_020526.1|WP_002942403.1|1773556_1773847_-|30S-ribosomal-protein-S6
MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATIVESKAWEKRRLAYEIKDFREGLYHIVNVEANNDEALKEFDRLSKINGDILRHMIVKLDA
>NC_020526.1|WP_011922710.1|1774086_1775250_+|IS30-family-transposase
MKNKHLTLSDRNDIQIGIEQLKPFSAIAAKLGKDPSTISKEVRRNRVIKENSSTSNCEACPLLKKTPYVCNACPKKRSNCGYQKQFYYAKRAQLDYEVKLSDSRTGVALNKEEFYRMDEIVSAAIQKGQHLNHIIASNEMSASRASIYRYLEKGYLSTKPIDFPRVVKFRKRRIRNLQPIPKIAKEGRSYEDFQRFLTEKGISYWLEMDTVTGRIGGKVLLTFNLSFCNFIFAQLLDNKTANEVAKHLYAIKNDLHQKEMDFCEIFPVILTDNGGEFARVDDIEMDVRGESKLFFCDPNRSDQKGRIEKNHTLIRDILPKRSSFDNLTQEDINLVCSHINSVKRASFNGKSAYELFTFTYGEELATLLGISKIDPENVIQSPRLLDK
>NC_020526.1|WP_012027737.1|1775568_1776558_-|lipoate--protein-ligase
MKYIVNNSNDPAYNIALEAYAFKELTDIDEIFILWINEPAIIIGKHQNAIEEINKEFTDEKGIHVVRRLSGGGAVYHDLNNLNYTIISNKADEGAFDFKTFSKPVIDTLATLGVEANFTGRNDLEIDGKKICGNAQAYAKGRMMHHGCLLFDVDMSVLASALKVSKDKIESKGVKSVRARVTNINNELPDKMTVLEFKDAILNQMKQEYPEMDEYVLTEDDLARIQEIRDSQFATWDWTYGQTPEYTVERSVRYPAGKITTYIKAEKSVIESIKIYGDFFGIGDVADVEDLLVGTRYEYADVLAKLQEIDTTHYFSRMTTEEVAKAIVA
>NC_020526.1|WP_012027738.1|1776687_1777878_+|hypothetical-protein
MSKHLKSFLIFYLAASIFLPFMWFINAPLICFVLPLYLTWKNIRHFWDLLKKQLKEYSFWINDGLIFFLGTGLSWLALEMAQVVYVDWPETLVNNQIHSPMQTEAWSGQFFLLLLGVLAYLVLNIFQTKLLPPLLTVLLISCLYPSFVFAVLWTIQLSSLIETDFFTYCYLCLVPFNICLIYSRTILQTIQLWQAELAKQSNPRFPRLSALLQKSLSLPIWLLFFSLPYLAVLGSYLILFGQKPDQLLQMWTETSDWALSEKISPPNAFYDEHYLCTVGAAGHRKLVKPIRMGERHGHRVVVNRQLQIANAFEQILEERCPRLHRCVRSNYDRYGYPISKHIRKAWQADLIYLIMKPAEWLFLIVIYLHDRQPENRIAVQYLPLSKNLLPQENTSN
>NC_020526.1|WP_012027739.1|1777929_1779690_-|dihydrolipoyl-dehydrogenase
MAIEIIMPKLGVDMQEGEIIEWKKQEGDFVNEGDVILEMMSDKTSMELEAEESGVLLKIVHGNGATVPVTEVIAYLGAEGESVEVGAALAPAEVAQATADLKAAGLEVPATPAAAPQAPKAELAADEYDMVVVGGGPAGYYAAIRGAQLGGKIAIVEKSEFGGTCLNKGCIPTKTYLKNAEILDGLKIAAERGINLASTNYTVDMDKTVDFKNKVVKTLTGGVQGLLKANKVTIFNGLGQVNPDKTVVIGDKVIKGRSIILATGSKVSRINIPGIDSKLVLTSDDILDLREIPKSLTVMGGGVVGVELGLVYASYGTEVTVVEMADRIIPGMDREVSVELQKVLSKKGMKFLTSVGVSEIVEANNQLTIKLNDGSEIVSEKALLSIGRVPQLAGLENLNLELDRGRIKVNEYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENAIHGNHHKAKLDFTPAAVYTHPEIAMVGLTEDQAIEKYGKENILIGRNSFTGNGRAIASNEAHGFVKVIADKKYHEILGVHIIGPVAAEMINEAATIMESELTVDDVAASIHGHPTFSEVMYEAFLDVLGVAIHNPPKRK
>NC_020526.1|WP_002937767.1|1779963_1781352_-|dihydrolipoamide-acetyltransferase
MAIEIIMPKLGVDMQEGEIIEWKKQEGDFVNEGDVILEMMSDKTSMELEAEESGVLLKIVHGNGATVPVTEVIAYIGAEGETVEAGASSAPAVEPAAAIEEVPAGRTPVIVAPATAAKPQGSGKVRATPAARKLARELGIDLGLVPGTGANGRVHKVDVEDFKGAAPKATPLAARIAADQGVDLSTLTGSGVNGKIVKNDVLAVLAPVAVETAAPVPKAEEKPAKELPEGVEIIKMSPMRKAISKGMVNSYLTAPTFTLNYDIDMTNLMALRKQVLEPIMNKTGLKVTFTDLIGLAVVRTLMKEEHRYMNASLINDAQEIELHKFVNLGIAVGLDDGLVVPVVHGADKMSLSDFVVASKDVIKKAQSGKLKGAEMSGSTFSITNLGMFGTKTFNPIINQPNSAILGVASTVQTPVVIDGEIKIRPIMALCLTIDHRIIDGMNGAKFMVDLKNLLENPLELLI
>NC_020526.1|WP_002942393.1|1781692_1782688_-|alpha-ketoacid-dehydrogenase-subunit-beta
MAETKVMALREAINLAQSEEMRKDEKVFLMGEDVGIYGGDFGTSVGMLDEFGPKRVRDTPISEAAIAGSAVGAAQTGLRPIVDLTFMDFITIALDAIVNQAAKTNYMFGGGLKTPVTFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGTANDAKGLLKSSILDNNPVIFLEPKALYGKKEEVNLDPDFYIPLGKGEIKREGTDVTIISYGRMLERALKAAEEVAAEGISVEVVDPRTLIPLDKELIIESVKKTGKVILVNDAYKTGGFIGEIASIITESEAFDYLDAPIIRIASDDVPVPYANILENAVLPNVEKIKAAIYKQVNKG
>NC_020526.1|WP_012775325.1|1782974_1783943_-|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha
MVSITKEQHLDMFLKMQQIRDVDMKLNKLVRRGFVQGMTHFSVGEEAAAVGPIAGLTDEDIIFSHHRGHGHVIAKGIDINGMMAELAGKATGTSKGRGGSMHLANVEKGNFGSNGIVGGGYALAVGAALTQQYLGTDNIVIAFSGDSATNEGSFHESMNLAAVWNLPVIFFITNNRYGISTDISYSTKIPHLYQRAAAYGIPGHYVEDGNDVIAVYEKMQEVIEYVRAGKGPAMVEVESYRWFGHSTADAGVYRTKEEVNEWKAKDPLKKYRKYLTENKIATDEELDAIEAQVAEQVEASVKFAQESPDPDISVAYEDVFVD

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Crispr_ID: NC_020526_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_020526_2

1816930-1817053

Orphan

Consensus_repeat	Method
CCAATCAACCACTACTGCGCTAAGATGTTGAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_020526_2

>merge|NC_020526|2|1816930-1817053|CRISPRCasFinder
CCAATCAACCACTACTGCGCTAAGATGTTGACACTAACGTTGAGAAGCGGTACAGGGCTTGAGCCCAGCTTCACTCCACTGGACTGTTAAACCCAATCAACCACTACTGCGCTGAGATGTTGAC

>NC_020526|2|2|1816930-1817053|CRISPRCasFinder
CCAATCAACCACTACTGCGCTAAGATGTTGAC	ACTAACGTTGAGAAGCGGTACAGGGCTTGAGCCCAGCTTCACTCCACTGGACTGTTAAAC
CCAATCAACCACTACTGCGCTGAGATGTTGAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_020526.1\|WP_012027765.1\|1812967_1813408_-\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	unknown	unknown	gnl\|CDD\|273918
NC_020526.1\|WP_002938143.1\|1804428_1805385_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NC_020526.1\|WP_012028491.1\|1820208_1821774_+\|ABC-transporter-substrate-binding-protein/permease	unknown	unknown	gnl\|CDD\|270345
NC_020526.1\|WP_012775333.1\|1814621_1815884_-\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NC_020526.1\|WP_002938151.1\|1811202_1812618_-\|Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl\|CDD\|131035
NC_020526.1\|WP_012027766.1\|1813394_1814618_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NC_020526.1\|WP_009910800.1\|1822635_1822845_-\|hypothetical-protein	unknown	unknown	unknown
NC_020526.1\|WP_012027774.1\|1822930_1823833_-\|SPFH-domain-containing-protein	unknown	unknown	gnl\|CDD\|259805
NC_020526.1\|WP_009910805.1\|1826538_1827015_-\|acetolactate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|183365
NC_020526.1\|WP_012027759.1\|1805386_1806328_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224048
NC_020526.1\|WP_012775335.1\|1821766_1822510_+\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NC_020526.1\|WP_012775334.1\|1818395_1819118_-\|adaptor-protein-MecA	unknown	unknown	gnl\|CDD\|235030
NC_020526.1\|WP_012027770.1\|1819245_1820082_-\|undecaprenyl-diphosphate-phosphatase	unknown	unknown	gnl\|CDD\|234712
NC_020526.1\|WP_012775331.1\|1807705_1809496_-\|oligopeptide-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173875
NC_020526.1\|WP_002938165.1\|1815900_1816674_-\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NC_020526.1\|WP_012027769.1\|1817226_1818399_-\|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	unknown	unknown	gnl\|CDD\|133463
NC_020526.1\|WP_009910803.1\|1825375_1826398_-\|ketol-acid-reductoisomerase	unknown	unknown	gnl\|CDD\|235491
NC_020526.1\|WP_002937416.1\|1823842_1825093_-\|threonine-ammonia-lyase-IlvA	unknown	unknown	gnl\|CDD\|236318
NC_020526.1\|WP_002942324.1\|1806330_1807329_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521
NC_020526.1\|WP_012775332.1\|1809708_1810950_+\|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl\|CDD\|224600

Protein	Function_ID	Function_description	E-value
NC_020526.1\|WP_012027765.1\|1812967_1813408_-\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	gnl\|CDD\|273918	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family. Three iron-sulfur cluster assembly systems are known so far. ISC is broadly distributed while NIF tends to be associated with nitrogenase in nitrogen-fixing bacteria. The most recently described is SUF, believed to be important to maintain the function during aerobic stress of enzymes with labile Fe-S clusters. It is fairly widely distributed. This family represents one of two different proteins proposed to act as a scaffold on which the Fe-S cluster is built and from which it is transferred. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	8.16406e-68
NC_020526.1\|WP_002938143.1\|1804428_1805385_-\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.06681e-112
NC_020526.1\|WP_012028491.1\|1820208_1821774_+\|ABC-transporter-substrate-binding-protein/permease	gnl\|CDD\|270345	cd13627, PBP2_AA_binding_like_2, Substrate-binding domain of putative amino acid-binding protein; the type 2 periplasmic-binding protein fold. This putative amino acid-binding protein belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.18368e-91
NC_020526.1\|WP_012775333.1\|1814621_1815884_-\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	4.97321e-124
NC_020526.1\|WP_002938151.1\|1811202_1812618_-\|Fe-S-cluster-assembly-protein-SufB	gnl\|CDD\|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_020526.1\|WP_012027766.1\|1813394_1814618_-\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_020526.1\|WP_012027774.1\|1822930_1823833_-\|SPFH-domain-containing-protein	gnl\|CDD\|259805	cd03407, SPFH_like_u4, Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model summarizes an uncharacterized family of proteins similar to stomatin, prohibitin, flotillin, HflK/C (SPFH) and podocin. The conserved domain common to the SPFH superfamily has also been referred to as the Band 7 domain. Many superfamily members are associated with lipid rafts. Individual proteins of the SPFH superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. Microdomains formed from flotillin proteins may in addition be dynamic units with their own regulatory functions. Flotillins have been implicated in signal transduction, vesicle trafficking, cytoskeleton rearrangement and are known to interact with a variety of proteins. Stomatin interacts with and regulates members of the degenerin/epithelia Na+ channel family in mechanosensory cells of Caenorhabditis elegans and vertebrate neurons and participates in trafficking of Glut1 glucose transporters. Prohibitin may act as a chaperone for the stabilization of mitochondrial proteins. Prokaryotic HflK/C plays a role in the decision between lysogenic and lytic cycle growth during lambda phage infection. Flotillins have been implicated in the progression of prion disease, in the pathogenesis of neurodegenerative diseases such as Parkinson's and Alzheimer's disease and, in cancer invasion and metastasis. Mutations in the podocin gene give rise to autosomal recessive steroid resistant nephritic syndrome.	3.71678e-128
NC_020526.1\|WP_009910805.1\|1826538_1827015_-\|acetolactate-synthase-small-subunit	gnl\|CDD\|183365	PRK11895, ilvH, acetolactate synthase 3 regulatory subunit; Reviewed.	1.6123e-73
NC_020526.1\|WP_012027759.1\|1805386_1806328_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	2.10004e-119
NC_020526.1\|WP_012775335.1\|1821766_1822510_+\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	7.30548e-147
NC_020526.1\|WP_012775334.1\|1818395_1819118_-\|adaptor-protein-MecA	gnl\|CDD\|235030	PRK02315, PRK02315, adaptor protein MecA.	2.58092e-83
NC_020526.1\|WP_012027770.1\|1819245_1820082_-\|undecaprenyl-diphosphate-phosphatase	gnl\|CDD\|234712	PRK00281, PRK00281, undecaprenyl-diphosphate phosphatase.	1.49616e-101
NC_020526.1\|WP_012775331.1\|1807705_1809496_-\|oligopeptide-ABC-transporter-substrate-binding-protein	gnl\|CDD\|173875	cd08510, PBP2_Lactococcal_OppA_like, The substrate binding component of an ABC-type lactococcal OppA-like transport system contains. This family represents the substrate binding domain of an ATP-binding cassette (ABC)-type oligopeptide import system from Lactococcus lactis and other gram-positive bacteria, as well as its closet homologs from gram-negative bacteria. Oligopeptide-binding protein (OppA) from Lactococcus lactis can bind peptides of length from 4 to at least 35 residues without sequence preference. The oligopeptide import system OppABCDEF is consisting of five subunits: two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and also is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NC_020526.1\|WP_002938165.1\|1815900_1816674_-\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	2.74827e-148
NC_020526.1\|WP_012027769.1\|1817226_1818399_-\|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	gnl\|CDD\|133463	cd06853, GT_WecA_like, This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate molecule and N-acetylglucosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylglucosamine precursor. WecA participates in the biosynthesis of O antigen LPS in many enteric bacteria and is also involved in the biosynthesis of enterobacterial common antigen. A conserved short sequence motif and a conserved arginine at a cytosolic loop of this integral membrane protein were shown to be critical in recognition of substrate UDP-N-acetylglucosamine.	9.66017e-81
NC_020526.1\|WP_009910803.1\|1825375_1826398_-\|ketol-acid-reductoisomerase	gnl\|CDD\|235491	PRK05479, PRK05479, ketol-acid reductoisomerase; Provisional.	0
NC_020526.1\|WP_002937416.1\|1823842_1825093_-\|threonine-ammonia-lyase-IlvA	gnl\|CDD\|236318	PRK08639, PRK08639, threonine dehydratase; Validated.	0
NC_020526.1\|WP_002942324.1\|1806330_1807329_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.71068e-159
NC_020526.1\|WP_012775332.1\|1809708_1810950_+\|D-alanyl-D-alanine-carboxypeptidase	gnl\|CDD\|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	5.36323e-91

>NC_020526.1|WP_002938165.1|1815900_1816674_-|Fe-S-cluster-assembly-ATPase-SufC
MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKSTLSAAIMGNPSYEVTQGEILFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLRAAMNAGKEDEDKISVRDFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLLMLEPTFALLDEIDSGLDIDALKVVSKGINAMRGEGFGAMIITHYQRLLNYITPDVVHVMMEGRVVLSGGPELAQRLEKEGYVQVAAELGIDYKEDDI
>NC_020526.1|WP_012775333.1|1814621_1815884_-|Fe-S-cluster-assembly-protein-SufD
MTKEKIQEFSALQAEPTWLTDLRLKAFDKIAELDLPVIERVKFHRWNLGDGSLATNDEIGAVPDFTAIGDNPMLVQVGSQTILEQLPVALVEKGVVFTDFASAMDVIPDVLEKYLGAAVAYDEHKLAAYNTAYFNATAVLYVPDNVEIDQPVEALFYQDSTSPVAFNKRVLIIAGKNAKLNYLERFESLGDGAATTSANIVVEVIALAGSQIKFAAIDRLGKHLDTYLNRRGYLGNDATIDWAIGLLNEGNVVADLDSELKGNGSHANLKVVGLSSGRQVQGVDTRVTNYGHNSVGHILQHGVILESGTLTFNGIGHIVRGAKGADAQQESRVLMLSDKARSDANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDRATAERLVVRGFLGSVITEIPVKEVRDQLIAVIEEKLTKR
>NC_020526.1|WP_012027766.1|1813394_1814618_-|cysteine-desulfurase
MDLERIRKEFSILDQVVNDEPLVYLDNAATTQKPQQVLDVLADYYQKDNANVHRGVHTLSERATTRYEAARQKVADFIQAKSSKEILFTRGTTTSLNWVAQFAKEILQPDQEVIISVQEHHSNIIPWQQACQQTGAKLRYVTLKDGELDMDHLRSLLSSKTKFVSLAHVSNVLGGVVPIGEIAELVHQVGAYLVVDGAQSVPHMGVNVQELDVDFYAFSGHKMLGPTGIGILYGKEELLNLMSPVEFGGEMIDFVYEQSATWKELPWKFEAGTPNIAGAIGLGAAIDYLTEIGMDAIQAHEAELVDYVFPKLQAIPGLTIYGSQDLSKRTGVIAFNLDDLHPHDVATALDYEGVAVRAGHHCAQPLLRYLQVPATVRASFYIYNTKADCDKLVEAIIKTKEFFNGPI
>NC_020526.1|WP_012027765.1|1812967_1813408_-|SUF-system-NifU-family-Fe-S-cluster-assembly-protein
MALSRLDSLYMAVVSEHSKSPRHRGSLDGVEKLELHNPTCGDVIELSVKIEKDVITDIAFDGVGCTISTASASMMTEAVLGKEISQIQELAEIFSQMVRGQEDPRQKELGDASLLAGVAKFPQRIKCATLPWNALKKALSLRSSAE
>NC_020526.1|WP_002938151.1|1811202_1812618_-|Fe-S-cluster-assembly-protein-SufB
MSEERIEPTPIDLGEYKFGFHDENVELVASTGKGLNEEVIREMSRIKGEPEWMLEFRLKSYETFKKMPMQTWGADLSELDFDDIVYYQKPSDKPARSWDDVPDKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEYDKHGIIFTDTDTALKEHPELFKKYFGKLVPPSDNKLAALNSAVWSGGTFIYVPKGVKLDIPLQTYFRINNEGTGQFERTLIIVDEGASVHYVEGCTAPTYSTASLHAAIVEIIAHEGAYMRYTTIQNWSDNVYNLVTKRARAEKNATVEWIDGNLGAKTTMKYPAVYLEGEGARGTMLSIAFANKGQVQDTGAKMIHNAPRTSSSIVSKSIARGGGEVNYRGQVTFAKNSAKSISHIECDTIIMDDISKSDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELPMEYAVELNRLIAYEMEGSVG
>NC_020526.1|WP_012775332.1|1809708_1810950_+|D-alanyl-D-alanine-carboxypeptidase
MRKLLLTLTTILAVFLTSTPILAEDFSVAAKHAIAVEVSSGKILYEQDAETKASIASISKTLSIYLVYEALAKGEITLDTMVDISDYPYSLTSNTELSNVNLDERSYSVRDLLNASLITSSNSAIIALAEKIAGSEAAFVDRMKAKVQEWGITDTKIVNVSGLDNTDLGENIYPGSSPEDVNMFSALDVAIIARRLILDYPQVLDITSLNAYDFGGYTYYSTNQMLSDGTHARGGVDGLKTGTSNSAGSSFLATTQQAGMRIITVVLNANDGLTSPENRFVATNDLMNYVYSNFSLVTLVKKSEAFGDSKIKVFNGEKETSPVVAAADLTVVQRNQTDNVPTATFTTDIKEIDAPLKAGTLVSKLQLKDQDLIGKGYISEQTGVDMIIPSDMKEASWPFSWWNQFVRYVNEKL
>NC_020526.1|WP_012775331.1|1807705_1809496_-|oligopeptide-ABC-transporter-substrate-binding-protein
MKKTTKLFALAGVTLLSASVLAACGSKQSGAAKQELSFPAEVKQDGTAVADAQLKYAWVSPTTSSGLLIDELTENTTDSTFGGMVDISMFGYDGERKLDDSGLAKAEFDVKGKKITVSLTGKDYKWSDGESFTINDYIFTIKSMASKDYTGIRFDDKFLNIEGMQEFVDGKASDISGIKKVDDYTVELTVKEMSPSMMYAGGDVPAYIQPEHIYKDIPVADWEKSEYSRTAKLVGMGPWKIKEIVNGESITYVPNEYFFKGTKPKTSSLKIDIVSPDTIVSEMKAGNYDIAEMPVDQLDSYKDASNLNIVGQLESSYEYISFNFGKYDEAAGKNVMDENAKMNDVKLRQAIAYAIDTKTAGKSLYNGLYHPAKSLIISFFGDIHDSELEGYSYNPEKAKKLLDEAGYKDVDGDGIREGKDGKAFKITFAARKRTEANEALVQQYIAWWKEVGLNVELYTGRTVEGKSFYNSVQANDAAIDMYAGGWSTGYDPNPSGLWGPIAAFNMSRFVSDENTKLLEAISSAESFDDKKNVENYKAWQKYAHEQAFAIPTFESEKITAVNKRVKSYDTKYGSASGTGLAYEGIELTADKGVVAE
>NC_020526.1|WP_002942324.1|1806330_1807329_-|ABC-transporter-ATP-binding-protein
MATEKPLLDIKDLHVGFRIGDDYFDAVDGVDISLQKNEILAIVGESGCGKSTLATTIMGLHNPLNTKITGSIQYNDMELIGMDEAKYNTVRGNDIGMIFQDPLASLNPLMTIGAQIDEALFYHTDLDANARTERVLELLAQVGIPNPKRTFKQYPHELSGGMRQRIIIAMALSCKPPIIIADEPTTALDVTIQAQILDLLNDIQAETGSGIILITHDLGVVAETADRVAVMYGGQFVEVAPVEELFTNPKHPYTRSLLKSNPQSGSEGGDLHVIEGIVPPITKMVRKGCRFAPRIPWIGAEAHEENPSMHEVGPNHFVRCTCHETFYFEGEA
>NC_020526.1|WP_012027759.1|1805386_1806328_-|ABC-transporter-ATP-binding-protein
MGFIEVKDLKVHYPIRSGFFNRVTDHVYAVDGVNIEFEEGKTYGLVGESGSGKSTIGKAIIGLERATSGQIIYEGQDVTNKSRGKKGNFNRDVQMIFQDSLSSFNPKKRILDIIAEPIRNFDRLSPDEEKKKVLQLLDTIGLNEEALIKYPHEFSGGQRQRIGVARALASNPRLIIADEPVSALDLSVQAQVLNYMKRIQDEFKLSYLFISHDLGVVQHMCDELFIMYRGRFVETGNKNDIYNNPQHIYTKRLLSAIPTIDPLNRLKNKEKRLAAEKEYQEMQGQYYDENGRVYDLRSFSETHQVALPEGGQN
>NC_020526.1|WP_002938143.1|1804428_1805385_-|ABC-transporter-permease
MWKTVLRRLLMMIPQIIILSVIAFFVAKMMPGDPFTGLIDPNIDPAIIEQKRIAAGYYDPIPVQYFRWVGNLLQGDFGQSVIFKQPVVDVIMQRLNNTIGLSLLTMVLTYLIALPLGMIAGRYQNSLADKIIGVYNFLTFSTPTFVFAILMLWMFGFSLGWFPTRGSISGGVEGFAATLSRLHHMILPAITMAILSTTVTIQYLRTGIIDAKSQDYVRTARAKGVPERVVYNRHIFRNSILPIASFLGYELTGLIGGSIFIENIFTYPGIGQLFFNSISSRDYSVILALLLVFGMGTLLGTLISDIIMSIVDPRIRVK
>NC_020526.1|WP_012027769.1|1817226_1818399_-|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase
MIPFALKYIMVIITTMVISAIATPLVRFMSLRVGAVDNPNARRINKVPMPSAGGLAIFVAFTISVLWFLPGIVTRVNYHGTYLHYIWPLVLASSIIVLTGFIDDVKELKPAPKMFGILAAATIIWIFTEFRFDSFKIPFGGPFLQFPVWLSFLLTVLWIVSITNAVNLIDGLDGLVSGVSIISLTTMGIVSYFFLHDSNIFLTLTIFVLVAAIVGFLPYNYNPAIIYLGDTGALFIGFMIGVLSLQGLKNSTAVAVVTPMIILGVPITDTVVAIIRRKLSGQKIYEADKMHLHHRLLSLGLTHRGTVLVIYAISFLFSLTSLLLNVSSRIGGILLLVTMGLGIEILCELIGIFGINRTPLLNLLRFIGNSSYRQEKIAKYKKCCEEKKRK
>NC_020526.1|WP_012775334.1|1818395_1819118_-|adaptor-protein-MecA
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDLDQNLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFTFVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV
>NC_020526.1|WP_012027770.1|1819245_1820082_-|undecaprenyl-diphosphate-phosphatase
MLLELLKAIFLGIIEGVTEWLPVSSTGHLILVQEFVKLNQSKNFLEMFNIVIQLGAILAVMTIYFKKLNPFQPGKTKRDIQLTWQLWAKVVIACIPSILIAVPLDNWFEAHFNFMVPIAIALIVYGIAFIWIENRNRGIEPQVTDLAKMSYKTALLIGCFQVLSIVPGTSRSGATILGAIILGTSRSVAADFTFFLGIPTMFGYSGLKAVKYFLDGNSLNMEQVWILLVASVTAYLVSLVVIRFLTDFVKKHDFTVFGYYRIILGAILLVYAFITFLF
>NC_020526.1|WP_012028491.1|1820208_1821774_+|ABC-transporter-substrate-binding-protein/permease
MKRKLSIFLLTLIAVFSVTTGVRADEYLRVGMEAAYAPFNWTQEDDSNSAVPIEGTNQFANGYDVQVAKKIAASMDKELLVVKTKWEGLVPALTSGKIDMIIAGMSPTEERKKEIAFSDSYYTSIPTLVVRSDSQYANATSLEDFAGAKITAQQGVYLYDLIDQIEGANKQTAMGDFSQIRQALESGIIDAYVSERPEGRTAEAANKAFKMVELADSFETNAEDVTIAVGMRKDDERIAQVNEVLATISEEEQIALMDDMIENQPVEEASEGETPSFFAQVWNIVVNNWQQLLRGTGMTLLISILGTIIGTAIGLLIGVFRTAPKAANKALAIGQKVLGWIINIYIEIFRGTPMIVQSMVIYYGTAQAFGLNLDRTLAAIFIVSINTGAYMSEIVRGGIFAVDKGQFEAATALGFTHNQTMRKIVLPQVIRNILPATGNEFVINIKDTSVLNVISVVELYFSGNTVATQTYQYFQTFTVIAIIYFILTFTVTRILRAVEKYFDTDTYTTGANQMQVEVPHD
>NC_020526.1|WP_012775335.1|1821766_1822510_+|amino-acid-ABC-transporter-ATP-binding-protein
MTKNVILEIKNLKKSYGQNQVLKDISISVEKGEVISIIGSSGSGKSTFLRSINLLETPTEGQILYHGQDVLAKGYDLTTYREKLGMVFQSFNLFNNLNVLENAIVAQTTVLKRDRAEAEKIAKENLNKVGMTEQYWQAKPSQLSGGQKQRVAIARALSVDPEVILFDEPTSALDPEMVGEVLKTMQDLAKSGLTMLIVTHEMEFARDVSDRVIFMDKGVIAEEGSPQQIFENPQEERTREFLQRFLG
>NC_020526.1|WP_009910800.1|1822635_1822845_-|hypothetical-protein
MTSYEKVAAVVGWVREKKITGYRISKETNAREMSVIALAQGRAKIDNISFATALGLIDFYDKNHKKFEN
>NC_020526.1|WP_012027774.1|1822930_1823833_-|SPFH-domain-containing-protein
MVFGPIVFIGSFLFFVLIALILIASGLYVVKQQTVAIIERFGKYQKTSTSGINFKIPFGVDVIAARIQLRMLQSEIVVETKTQDNVFVTMNVATQYRVNENNVTDAYYKLMHPEAQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQKQVAEEMSTYGYVIVKTLITKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQRKAIVDGLADSIRELKESNVSLSEEQIMSILLTNQYLDTLNNFAQGGNQTIFLPGNPEGVEDIRTQILSSLRAK
>NC_020526.1|WP_002937416.1|1823842_1825093_-|threonine-ammonia-lyase-IlvA
MITAKNVEQAYSVLKRVVVRTPLDYSRYLSEKYGATIYLKRENEQRVRSFKIRGAYYAISQLTDDEKSRGVVCASAGNHAQGVAYTCQEMQIPATIFMPITTPQQKIGQVKFFGGDYVEIRLVGDTFDESAKAAQDYTQESGKTFIDPFDDENVQAGQGTVAYEILEEAEEQTISFDQILVPIGGGGLVAGVSAYLKEHAPEIKIVGVEASGARSMKAAFDKGRPVKLDQIDKFADGIAVQKVGKSTYEVARKYVDRLIGVDEGWISGTILDLYSKLGIVAEPAGAATIAALEVVKDQIKGQTICCIISGGNNDINRMPEMEERALIYEGIKHYFVVNFPQRPGALREFVNDILGPNDDITRFEYIKRANKGTGPVLIGIALGDKTDYTQFISRLEEFDPQYINLHENDSLYKMLV
>NC_020526.1|WP_009910803.1|1825375_1826398_-|ketol-acid-reductoisomerase
MTVTMQYEKDVTVAALDGKRIAVIGYGSQGHAHAQNLRDTGHDVIIGVRAGKSFDKAKEDGFETFEVAEAAKQADVIMILAPDEIQADLYNEEIAPNLEAGNALGFAHGFNVHFEFIKVPADVDVFMCAPKGPGHLVRRTFEEGFGVPALYAVYQDATGNAKHIAMDWAKGVGSARVGLLETTFKEETEEDLFGEQAVLCGGLTALMQAGFEVLTEAGYAPELAYFEVLHEMKLIVDLVYEGGFKKMRQSISNTAEFGDYVSGPRVITDQVKENMKAVLADIQSGKFANDFVNDYKAGRPRMEAYRKEAENLEIEKVGAELRKAMPFVGRNDDDAFKIYN
>NC_020526.1|WP_009910805.1|1826538_1827015_-|acetolactate-synthase-small-subunit
MRRMLTAKLRNSSGVLNRFTGVLSRRQINIESISVGPTEVDGISRVTVIVDVVSHDEVEQIIKQLNRLIDVVRVRDLTDIPHLEREVILVKISAPPTKRAEILAIIQPFRANVVDVAPHSITIQMTGDGDKIDALLRVIQPYGIKNIARTGATGFSRD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

31434 : 41695

Microbacterium_phage(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012774881.1\|31434_35154_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	8.6e-39	26.9
WP_011921648.1\|35156_36611_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-58	35.4
WP_012774882.1\|36666_37689_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A127KMF9	Cyanophage	1.3e-58	42.7
WP_011922533.1\|37685_38237_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.6e-26	38.5
WP_015445081.1\|38246_39794_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.0e-74	47.6
WP_011921654.1\|41206_41695_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.7e-17	45.0

DBSCAN-SWA_2

545436 : 558549

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011922101.1\|545436_546075_-	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	1.0e-125	99.5
WP_011922102.1\|546137_548651_+	bifunctional DnaQ family exonuclease/ATP-dependent helicase	A0A1X9I5C8	Streptococcus_phage	0.0e+00	98.5
WP_011922103.1\|548810_549887_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.5e-193	99.2
WP_011922104.1\|549951_551190_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.0e-217	96.8
WP_011922105.1\|551199_551985_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	1.0e-130	95.4
WP_011922106.1\|552007_552412_-	TetR/AcrR family transcriptional regulator	A0A1X9I6A2	Streptococcus_phage	3.2e-64	99.3
WP_002938910.1\|552538_553390_+	DegV family protein	A0A1X9I5J4	Streptococcus_phage	1.3e-152	98.6
WP_015445143.1\|553488_554748_-	PLP-dependent aminotransferase family protein	A0A1X9I5H2	Streptococcus_phage	3.6e-239	98.6
WP_012775019.1\|554870_555605_+	peroxide stress protein YaaA	A0A1X9I5I0	Streptococcus_phage	1.5e-120	99.5
WP_012775020.1\|555709_557155_+	LCP family protein	A0A1X9I5X1	Streptococcus_phage	2.4e-226	99.5
WP_011922111.1\|557172_557862_+	capsular polysaccharide biosynthesis protein CpsC	A0A1X9I5E1	Streptococcus_phage	1.3e-110	96.1
WP_012775429.1\|557871_558549_+	tyrosine-protein kinase	A0A1X9I5D6	Streptococcus_phage	8.1e-121	99.1

DBSCAN-SWA_3

658695 : 716338

Streptococcus_phage(98.36%)

holin,terminase,tail,head,capsid,portal,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014636303.1\|658695_660501_+	recombinase family protein	A0A2I4R675	Erysipelothrix_phage	4.3e-153	52.7
WP_002941306.1\|660868_661039_+	hypothetical protein	A0A1X9I6E4	Streptococcus_phage	5.7e-23	100.0
WP_014636304.1\|661425_662643_+	macrolide efflux MFS transporter Mef(A)	A0A1B0RXG2	Streptococcus_phage	3.6e-204	93.1
WP_014636305.1\|662762_664226_+	Msr family ABC-F type ribosomal protection protein	A0A1B0RXA0	Streptococcus_phage	1.0e-253	97.9
WP_014636306.1\|664343_664643_-	hypothetical protein	A0A1B0RX98	Streptococcus_phage	1.8e-48	96.0
WP_014636307.1\|664629_664998_-	hypothetical protein	Q6DMX5	Streptococcus_phage	1.9e-60	98.4
WP_014636308.1\|664994_666410_-	Y-family DNA polymerase	M1Q231	Streptococcus_phage	1.2e-267	97.9
WP_153309563.1\|666414_666555_-	hypothetical protein	Q6DMX3	Streptococcus_phage	2.9e-17	97.8
WP_014636310.1\|666532_666760_-	hypothetical protein	A0A1B0RXB5	Streptococcus_phage	1.1e-37	100.0
WP_014636311.1\|666762_667452_-	helix-turn-helix transcriptional regulator	A0A1B0RXB1	Streptococcus_phage	9.1e-128	100.0
WP_014636313.1\|667727_669551_+	ImmA/IrrE family metallo-endopeptidase	A0A1B0RXB2	Streptococcus_phage	0.0e+00	100.0
WP_014636314.1\|669884_670454_+	hypothetical protein	A0A1B0RXB3	Streptococcus_phage	3.3e-107	100.0
WP_014636315.1\|670492_672448_-	hypothetical protein	A0A1B0RXB4	Streptococcus_phage	0.0e+00	100.0
WP_014636317.1\|672682_673231_-	DUF2815 family protein	A0A1B0RXA9	Streptococcus_phage	4.1e-99	100.0
WP_014636318.1\|673235_674357_-	DUF2800 domain-containing protein	A0A1B0RXB8	Streptococcus_phage	2.2e-219	100.0
WP_014636319.1\|674349_674673_-	hypothetical protein	A0A1B0RXB7	Streptococcus_phage	7.2e-51	100.0
WP_014636321.1\|675071_677357_+	hypothetical protein	A0A1B0RXC5	Streptococcus_phage	0.0e+00	98.4
WP_015445164.1\|677623_677923_+	VRR-NUC domain-containing protein	Q6DMV8	Streptococcus_phage	2.6e-47	95.9
WP_014636323.1\|677903_679280_+	DEAD/DEAH box helicase	A0A1B0RXH8	Streptococcus_phage	1.5e-254	96.3
WP_014636324.1\|679272_679749_+	hypothetical protein	A0A1B0RXB9	Streptococcus_phage	3.6e-83	98.7
WP_014636325.1\|679943_680126_+	hypothetical protein	A0A1B0RXC3	Streptococcus_phage	1.0e-25	98.3
WP_014636326.1\|680170_681208_+	methionine adenosyltransferase	Q6DMV3	Streptococcus_phage	2.4e-188	96.2
WP_014636327.1\|681209_681575_+	HNH endonuclease	A0A1B0RXJ3	Streptococcus_phage	7.3e-68	97.5
WP_014636328.1\|681873_682335_+	hypothetical protein	A0A1B0RXK7	Streptococcus_phage	2.5e-89	100.0
WP_014636329.1\|682306_683560_+	DNA modification methylase	A0A1B0RXJ0	Streptococcus_phage	3.3e-245	100.0
WP_014636330.1\|683559_684150_+	endonuclease	A0A1B0RXJ4	Streptococcus_phage	2.1e-16	100.0
WP_014636331.1\|684146_685421_+	DNA (cytosine-5-)-methyltransferase	A0A1B0RXI8	Streptococcus_phage	3.9e-249	100.0
WP_014636332.1\|685499_685748_+	hypothetical protein	A0A1B0RXJ1	Streptococcus_phage	5.2e-41	100.0
WP_014636333.1\|685749_685962_+	DUF4314 domain-containing protein	A0A1B0RXJ2	Streptococcus_phage	3.1e-34	100.0
WP_014636334.1\|685963_686194_+	hypothetical protein	A0A1B0RXI4	Streptococcus_phage	2.4e-40	100.0
WP_003058374.1\|686245_686719_+\|terminase	phage terminase small subunit P27 family	A0A1B0RXI5	Streptococcus_phage	1.6e-86	100.0
WP_015445169.1\|686715_688308_+\|terminase	terminase large subunit	A0A1B0RXJ8	Streptococcus_phage	0.0e+00	100.0
WP_014636336.1\|688367_688670_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	A0A1B0RXK3	Streptococcus_phage	1.2e-47	100.0
WP_014636337.1\|688669_689008_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A1B0RXL8	Streptococcus_phage	1.0e-55	100.0
WP_014636338.1\|689144_689489_+	hypothetical protein	A0A1B0RXK0	Streptococcus_phage	7.6e-59	100.0
WP_014636339.1\|689546_690830_+\|portal	phage portal protein	A0A1B0RXK4	Streptococcus_phage	1.8e-249	100.0
WP_014636340.1\|690822_691518_+\|protease	Clp protease ClpP	A0A1B0RXJ9	Streptococcus_phage	4.6e-127	100.0
WP_014636341.1\|691536_692742_+\|capsid	phage major capsid protein	A0A1B0RXK1	Streptococcus_phage	2.2e-230	100.0
WP_014636342.1\|692741_693002_+\|head,tail	phage gp6-like head-tail connector protein	A0A1B0RXK2	Streptococcus_phage	1.6e-40	100.0
WP_014636343.1\|693001_693340_+\|head,tail	head-tail adaptor protein	A0A1B0RXJ6	Streptococcus_phage	7.5e-59	100.0
WP_014636344.1\|693332_693701_+	hypothetical protein	A0A1B0RXJ7	Streptococcus_phage	5.9e-49	100.0
WP_014636345.1\|693707_694034_+	hypothetical protein	A0A1B0RXK6	Streptococcus_phage	1.2e-56	100.0
WP_014636346.1\|694035_694605_+	hypothetical protein	A0A1B0RXE2	Streptococcus_phage	1.3e-103	100.0
WP_014636347.1\|694615_695035_+	hypothetical protein	A0A1B0RXM7	Streptococcus_phage	3.3e-72	100.0
WP_015445172.1\|695217_698076_+	Tail tape measure protein gp18	A0A1B0RXL6	Streptococcus_phage	4.3e-248	100.0
WP_014636349.1\|698072_698795_+\|tail	phage tail protein	A0A1B0RXL3	Streptococcus_phage	3.1e-134	100.0
WP_014636350.1\|698796_703344_+	hypothetical protein	A0A1B0RXL0	Streptococcus_phage	0.0e+00	100.0
WP_014636351.1\|703356_703563_+	hypothetical protein	M1NSJ5	Streptococcus_phage	1.1e-25	100.0
WP_014636352.1\|703568_703937_+	hypothetical protein	A0A1B0RXK8	Streptococcus_phage	3.1e-66	100.0
WP_014636353.1\|703914_704310_+\|holin	phage holin family protein	A0A1B0RXK5	Streptococcus_phage	2.9e-46	100.0
WP_014636354.1\|704316_705786_+	LysM peptidoglycan-binding domain-containing protein	A0A1B0RXL4	Streptococcus_phage	2.6e-281	100.0
WP_014636355.1\|706007_707249_+	recombinase family protein	A0A1B0RXM0	Streptococcus_phage	3.7e-236	100.0
WP_079253086.1\|707187_708504_+	recombinase family protein	E4ZFN9	Streptococcus_phage	1.5e-251	97.9
WP_014636357.1\|708585_710322_+	hypothetical protein	E4ZFP0	Streptococcus_phage	0.0e+00	100.0
WP_001835223.1\|710798_710996_+	hypothetical protein	NA	NA	NA	NA
WP_042507186.1\|710963_711623_-	RibD family protein	A0A1B0RXM8	Streptococcus_phage	9.0e-125	99.5
WP_079253078.1\|711733_712141_-	WYL domain-containing protein	A0A1B0RXM3	Streptococcus_phage	2.8e-60	99.2
WP_001079938.1\|712113_712686_-	HTH domain-containing protein	A0A1B0RXM1	Streptococcus_phage	5.5e-102	99.5
WP_001096887.1\|712961_713756_-	aminoglycoside O-phosphotransferase APH(3')-IIIa	E4ZFP6	Streptococcus_phage	2.3e-154	100.0
WP_000627290.1\|713848_714391_-	streptothricin N-acetyltransferase Sat4	A0A1B0RXL7	Streptococcus_phage	8.9e-94	100.0
WP_001255866.1\|714387_715296_-	aminoglycoside nucleotidyltransferase ANT(6)-Ia	E4ZFP8	Streptococcus_phage	2.8e-177	100.0
WP_002321849.1\|715600_716338_-	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	3.7e-135	100.0

DBSCAN-SWA_4

762960 : 778304

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012775040.1\|762960_765198_+	DNA internalization-related competence protein ComEC/Rec2	M1PSD2	Streptococcus_phage	1.2e-99	96.7
WP_011922763.1\|765521_766178_+	CBS domain-containing protein	M1NSC5	Streptococcus_phage	2.7e-113	98.6
WP_011922194.1\|766271_767099_+	hypothetical protein	M1PFV6	Streptococcus_phage	1.0e-133	98.5
WP_011922195.1\|767104_768376_+	hypothetical protein	M1PLC8	Streptococcus_phage	1.3e-207	98.1
WP_002935357.1\|768412_769279_-	YitT family protein	M1Q1P6	Streptococcus_phage	4.6e-153	99.7
WP_012775041.1\|769453_770092_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.0e-112	98.1
WP_011922767.1\|770088_770973_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	5.6e-154	98.6
WP_002935361.1\|770992_771310_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	3.1e-54	100.0
WP_002935362.1\|771311_772175_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	2.1e-158	99.7
WP_011922200.1\|772644_773736_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	2.4e-207	100.0
WP_011922201.1\|773735_774293_+	GNAT family acetyltransferase	M1PSC3	Streptococcus_phage	5.9e-93	94.6
WP_014636364.1\|774346_775528_+	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	2.3e-219	99.5
WP_042507188.1\|775530_776037_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	2.7e-92	96.4
WP_002935368.1\|776020_776374_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.9e-60	100.0
WP_011922204.1\|776390_777290_-	cation transporter	M1Q1N9	Streptococcus_phage	5.1e-163	99.7
WP_012775042.1\|777476_778304_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	2.9e-152	100.0

DBSCAN-SWA_5

938612 : 945642

Bacillus_phage(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014636389.1\|938612_939452_+	thymidylate synthase	U5J9N5	Bacillus_phage	3.9e-88	55.7
WP_014636390.1\|939737_940250_+	dihydrofolate reductase	A0A076GDN3	Bacillus_phage	2.7e-20	36.6
WP_002934974.1\|940447_941674_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.2e-133	59.2
WP_012775089.1\|941729_942317_+	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_012028095.1\|942339_942753_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	4.3e-24	42.5
WP_011922364.1\|942856_943528_+	membrane protein	A0A1S5SAM6	Streptococcus_phage	3.0e-06	35.2
WP_002943192.1\|943809_945642_+	elongation factor 4	A0A2K9L2P9	Tupanvirus	2.2e-19	38.8

DBSCAN-SWA_6

1323800 : 1329581

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012027298.1\|1323800_1324550_-	ABC-F family ATP-binding cassette domain-containing protein	A0A1B0RXA0	Streptococcus_phage	3.4e-27	32.9
WP_012027299.1\|1324712_1325255_-	ATP-binding cassette domain-containing protein	A0A2I4R674	Erysipelothrix_phage	5.9e-21	35.1
WP_014636426.1\|1325241_1325514_-	hypothetical protein	NA	NA	NA	NA
WP_012027300.1\|1325769_1326573_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	2.8e-35	35.6
WP_012027301.1\|1326579_1327929_-	cell wall metabolism sensor histidine kinase VicK	W8CYF6	Bacillus_phage	2.1e-35	34.5
WP_004298854.1\|1327921_1328626_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.1e-38	39.8
WP_012027304.1\|1328819_1329581_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.0e-34	38.4

DBSCAN-SWA_7

1494614 : 1504656

Streptococcus_phage(90.0%)

integrase

attL 1485976:1485990|attR 1512066:1512080

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1485976:1485990	attL	NA	NA	NA	NA
WP_012775260.1\|1494614_1495157_-\|integrase	site-specific integrase	A0A1S5SCL7	Streptococcus_phage	1.1e-80	78.9
WP_014636468.1\|1495143_1495329_-	hypothetical protein	NA	NA	NA	NA
WP_012027449.1\|1495626_1497159_-	primase	A0A1X9I717	Streptococcus_phage	4.9e-105	42.3
WP_012027450.1\|1497173_1497746_-	hypothetical protein	NA	NA	NA	NA
WP_012027451.1\|1497738_1497939_-	hypothetical protein	NA	NA	NA	NA
WP_012775262.1\|1497950_1498154_-	membrane protein	A0A1X9I5T6	Streptococcus_phage	2.4e-20	73.1
WP_012027452.1\|1498174_1498492_-	hypothetical protein	A0A1X9I5Z6	Streptococcus_phage	1.3e-09	41.0
WP_012027454.1\|1498845_1499109_-	hypothetical protein	A0A1S5S7M1	Streptococcus_phage	1.0e-07	43.8
WP_012775263.1\|1499239_1499647_-	hypothetical protein	A0A1X9I5V7	Streptococcus_phage	1.8e-35	52.2
WP_012027456.1\|1499658_1499976_-	hypothetical protein	NA	NA	NA	NA
WP_012027457.1\|1499962_1500184_-	hypothetical protein	NA	NA	NA	NA
WP_012027458.1\|1500180_1500423_-	hypothetical protein	NA	NA	NA	NA
WP_012027459.1\|1500419_1500620_-	hypothetical protein	NA	NA	NA	NA
WP_014636470.1\|1500609_1500900_-	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	1.8e-08	40.7
WP_012027461.1\|1501217_1501406_-	helix-turn-helix transcriptional regulator	R9QNG3	Lactococcus_phage	2.0e-05	42.4
WP_012027462.1\|1501557_1502079_+	helix-turn-helix transcriptional regulator	A0A1X9I723	Streptococcus_phage	8.7e-14	65.1
WP_012028388.1\|1502134_1502827_+	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_012775264.1\|1503513_1504656_+\|integrase	site-specific integrase	A0A1S5S7K9	Streptococcus_phage	2.5e-69	39.7
1512066:1512080	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_020526

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection