CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_020453	Bradyrhizobium oligotrophicum S58, complete genome	3 crisprs	cas3,DEDDh,RT,csa3,WYL,PD-DExK	0	0	4	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_020453_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_020453_1

347173-347318

Orphan

Consensus_repeat	Method
CGCGTCGATCCGCGTACCGGCAA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_020453_1

>merge|NC_020453|1|347173-347318|CRISPRCasFinder
CGCGTCGATCCGCGTACCGGCAATGCCGAGATCTATGCGCTCGGCGTGCGCAACAGCGTCGGCGGCGACGTCGATCCGCGTACCGGCAAATACTGGTTCACGGAGAATGCGCGCGACTGGGTCAGCGACGATCTGCCGAGCGACAA

>NC_020453|1|1|347173-347318|CRISPRCasFinder
CGCGTCGATCCGCGTACCGGCAA	TGCCGAGATCTATGCGCTCGGCGTGCGCAACAGCGTCGGCGGC
GACGTCGATCCGCGTACCGGCAA	ATACTGGTTCACGGAGAATGCGCGCGACTGGGTC
AGCGACGATCTGCCGAGCGACAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_020453.1\|WP_015663479.1\|338295_339126_+\|FTR1-family-protein	unknown	unknown	gnl\|CDD\|272930
NC_020453.1\|WP_015663476.1\|337185_337536_+\|hypothetical-protein	unknown	unknown	unknown
NC_020453.1\|WP_015663493.1\|353556_354222_+\|glutathione-S-transferase	unknown	unknown	gnl\|CDD\|198298
NC_020453.1\|WP_015663488.1\|348752_349676_-\|2-dehydropantoate-2-reductase	unknown	unknown	gnl\|CDD\|183829
NC_020453.1\|WP_083938780.1\|337996_338284_+\|cupredoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|379208
NC_020453.1\|WP_015663487.1\|347891_348473_+\|cytochrome-c4	unknown	unknown	gnl\|CDD\|225418
NC_020453.1\|WP_015663475.1\|336553_337096_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_020453.1\|WP_015663485.1\|344750_346097_-\|amidase	unknown	unknown	gnl\|CDD\|223232
NC_020453.1\|WP_015663494.1\|354225_355632_-\|serine-hydrolase	unknown	unknown	gnl\|CDD\|224594
NC_020453.1\|WP_144058221.1\|352743_353316_-\|DUF2239-family-protein	unknown	unknown	gnl\|CDD\|378346
NC_020453.1\|WP_015663490.1\|350576_351185_-\|2-hydroxychromene-2-carboxylate-isomerase	unknown	unknown	gnl\|CDD\|239320
NC_020453.1\|WP_015663480.1\|339126_339801_-\|LON-peptidase-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|225362
NC_020453.1\|WP_015663484.1\|343337_344642_-\|nicotinate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235406
NC_020453.1\|WP_015663483.1\|341765_343226_-\|caspase-family-protein	unknown	unknown	gnl\|CDD\|334197
NC_020453.1\|WP_015663496.1\|357667_359059_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225179
NC_020453.1\|WP_042340489.1\|355799_357503_-\|gamma-glutamyltransferase	unknown	unknown	gnl\|CDD\|223482
NC_020453.1\|WP_015663481.1\|339863_340784_-\|thioredoxin	unknown	unknown	gnl\|CDD\|225660
NC_020453.1\|WP_015663489.1\|349783_350521_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187631
NC_020453.1\|WP_015663491.1\|351285_352638_-\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240543
NC_020453.1\|WP_015663482.1\|340988_341456_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176863

Protein	Function_ID	Function_description	E-value
NC_020453.1\|WP_015663479.1\|338295_339126_+\|FTR1-family-protein	gnl\|CDD\|272930	TIGR00145, Uncharacterized_protein_slr0964, FTR1 family protein. A characterized member from yeast acts as oxidase-coupled high affinity iron transporter. Note that the apparent member from E. coli K12-MG1655 has a frameshift by homology with member sequences from other species. [Unknown function, General].	9.63227e-23
NC_020453.1\|WP_015663493.1\|353556_354222_+\|glutathione-S-transferase	gnl\|CDD\|198298	cd03189, GST_C_GTT1_like, C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases. Glutathione S-transferase (GST) C-terminal domain family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. GSTs also show GSH peroxidase activity and are involved in the synthesis of prostaglandins and leukotrienes. The GST fold contains an N-terminal thioredoxin-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. GSH binds to the N-terminal domain while the hydrophobic substrate occupies a pocket in the C-terminal domain. GTT1, a homodimer, exhibits GST activity with standard substrates and associates with the endoplasmic reticulum. Its expression is induced after diauxic shift and remains high throughout the stationary phase. S. pombe GST-III is implicated in the detoxification of various metals.	1.7372e-50
NC_020453.1\|WP_015663488.1\|348752_349676_-\|2-dehydropantoate-2-reductase	gnl\|CDD\|183829	PRK12921, PRK12921, oxidoreductase.	1.23474e-144
NC_020453.1\|WP_083938780.1\|337996_338284_+\|cupredoxin-domain-containing-protein	gnl\|CDD\|379208	pfam13473, Cupredoxin_1, Cupredoxin-like domain. The cupredoxin-like fold consists of a beta-sandwich with 7 strands in 2 beta-sheets, which is arranged in a Greek-key beta-barrel.	8.73133e-29
NC_020453.1\|WP_015663487.1\|347891_348473_+\|cytochrome-c4	gnl\|CDD\|225418	COG2863, COG2863, Cytochrome c553 [Energy production and conversion].	5.79674e-20
NC_020453.1\|WP_015663475.1\|336553_337096_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.58685e-05
NC_020453.1\|WP_015663485.1\|344750_346097_-\|amidase	gnl\|CDD\|223232	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis].	2.1322e-105
NC_020453.1\|WP_015663494.1\|354225_355632_-\|serine-hydrolase	gnl\|CDD\|224594	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms].	1.35164e-35
NC_020453.1\|WP_144058221.1\|352743_353316_-\|DUF2239-family-protein	gnl\|CDD\|378346	pfam09998, DUF2239, Uncharacterized protein conserved in bacteria (DUF2239). This domain, found in various hypothetical bacterial proteins, has no known function.	1.8292e-94
NC_020453.1\|WP_015663490.1\|350576_351185_-\|2-hydroxychromene-2-carboxylate-isomerase	gnl\|CDD\|239320	cd03022, DsbA_HCCA_Iso, DsbA family, 2-hydroxychromene-2-carboxylate (HCCA) isomerase subfamily; HCCA isomerase is a glutathione (GSH) dependent enzyme involved in the naphthalene catabolic pathway. It converts HCCA, a hemiketal formed spontaneously after ring cleavage of 1,2-dihydroxynapthalene by a dioxygenase, into cis-o-hydroxybenzylidenepyruvate (cHBPA). This is the fourth reaction in a six-step pathway that converts napthalene into salicylate. HCCA isomerase is unique to bacteria that degrade polycyclic aromatic compounds. It is closely related to the eukaryotic protein, GSH transferase kappa (GSTK).	2.32203e-69
NC_020453.1\|WP_015663480.1\|339126_339801_-\|LON-peptidase-substrate-binding-domain-containing-protein	gnl\|CDD\|225362	COG2802, COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease [General function prediction only].	1.29702e-64
NC_020453.1\|WP_015663484.1\|343337_344642_-\|nicotinate-phosphoribosyltransferase	gnl\|CDD\|235406	PRK05321, PRK05321, nicotinate phosphoribosyltransferase; Provisional.	0
NC_020453.1\|WP_015663483.1\|341765_343226_-\|caspase-family-protein	gnl\|CDD\|334197	pfam00656, Peptidase_C14, Caspase domain.	2.40242e-21
NC_020453.1\|WP_015663496.1\|357667_359059_+\|MFS-transporter	gnl\|CDD\|225179	COG2270, COG2270, Permeases of the major facilitator superfamily [General function prediction only].	2.43745e-109
NC_020453.1\|WP_042340489.1\|355799_357503_-\|gamma-glutamyltransferase	gnl\|CDD\|223482	COG0405, Ggt, Gamma-glutamyltransferase [Amino acid transport and metabolism].	0
NC_020453.1\|WP_015663481.1\|339863_340784_-\|thioredoxin	gnl\|CDD\|225660	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones].	9.21337e-100
NC_020453.1\|WP_015663489.1\|349783_350521_-\|SDR-family-oxidoreductase	gnl\|CDD\|187631	cd05373, SDR_c10, classical (c) SDR, subgroup 10. This subgroup resembles the classical SDRs, but has an incomplete match to the canonical glycine rich NAD-binding motif and lacks the typical active site tetrad (instead of the critical active site Tyr, it has Phe, but contains the nearby Lys). SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.2015e-117
NC_020453.1\|WP_015663491.1\|351285_352638_-\|MATE-family-efflux-transporter	gnl\|CDD\|240543	cd13138, MATE_yoeA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	7.13001e-107
NC_020453.1\|WP_015663482.1\|340988_341456_+\|SRPBCC-family-protein	gnl\|CDD\|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	1.28701e-20

>NC_020453.1|WP_015663485.1|344750_346097_-|amidase
MSDQSDLPTPKAGAGVLELLRRFAADPAAAATYGEDCLKQTLAIEPRLKAFEYLPRDVTAKTGPLGGIPVAIKDIIATSDMPTTNGSPIYRDHVPDADAWVVERLRNLGATIFGKTVSTEFAWRHPGPTVNPWNPEHSPGGSSSGSAAAVAAGLVPLALGTQTLGSVIRPAAFNGVVGFKPSFGAVPRIGVHPLSPSLDHVGFFARCVDDVALALSLLTGTSDGDLHGRPLPGFAVDIELGITPLAKPRLAVARFSKWERAEPEQKAVFESVVDRLRSAGAVIEEIALTELDAINWDAITTIMLSEATTIFSDLIARYPDRVSDVMKSHVESGRSKTAMEYLAAKAAQAERQRALPAELDGFDAVLTLPAFGEAPHGLDWTGDAEYCAPWTFVGAPAVSLPAGFGRNGLPLGVQIAGRPRDDLRTLRVAKWVEATLAFDPGLPPLRRP
>NC_020453.1|WP_015663484.1|343337_344642_-|nicotinate-phosphoribosyltransferase
MTVTDIASRTYNHGWRLDPIVRSLLDTDFYKLLMLQMIREFYPNQMVTFSVINRTRRVRLGDVIDEGELRAQLDHARSIRFSKKELIWLAGNTFYGKTHMFSPEFIAWLANFRLPEYELRKSEGQYELHFHGPWTHTTMWEIPALAIVNELRSRQAMKGQGRFALDVLFARAKAKLWAKVERLRKLEGLRLSDFGTRRRHGFLWQRWCVEAVKEGLGSSFTGTSNVLLAMDNDLEAIGTNAHELPMVAAALAKDDDELRLAPYRILDQWRQTYAGNLLIALPDAFGTKAFLRDAPDWVADWTGFRPDSAPPIQAGEEIIAWWKSKGRDPRQKLLVFSDAMDVESIEQIHHRFSDRVRLSFGWGTNLTNDFVGCMPDGSADLDPISLVCKVTSVDGQPAVKLSDNPEKATGDPAEIDRYLRVFGDAGRVRTPVVV
>NC_020453.1|WP_015663483.1|341765_343226_-|caspase-family-protein
MRRVIGRVGRLLSATIVLVTAILTAAAPAAADKRVALVIGNSIHERAPLLDEPAADARLLADRLARLGFTLSGGAAQIDLGKTGFDRAIAEFKGRIADADIALIYYAGYGLNLNGTNYLVPVDAAPAKASDADTELRSLEAVLRELDGSPRRQNVVILDAFRSNPFEARGIAGLAAGLAPMQVPASTLLAFAAQPGRSGQHGKDNHGVYATALADALQQPGRRLIEPLIEAGIATRRATDRAQNPVVMFTPIDGETALNQAAEKAPGAASPAARQAAAPASTTPAQTKESATQDARTPGLVVLYDEDPAEPQGRRYAGSVAWRTETIKDAQSGQPTTAIRADIEVPERKMKLTLQLRQNRDPSMPASHLAEVTFRLGPDFPGGGISNLPGILMKTEEKARGTPLAGLAVKVTEGSFLVGFSNVEADRERNEQLLLGRQWFDIPLVYMNQRRGIIAIAKGPSGDKAFADAFAAWSLPATGKSIGAIK
>NC_020453.1|WP_015663482.1|340988_341456_+|SRPBCC-family-protein
MPKAYYSTVFTQSAAEIWQNIRDFNSYPIWIDGAGFSEIEDGRSGDAVGAVRHARYQDRHIRQRLLALSDVERFQTYEFCGPASLPVHDFQATLRVTPIVDGDRTFVEWWANFDCEPGARDELVATLRGWFGGWLESLRRTVALHHAEAAQEVRG
>NC_020453.1|WP_015663481.1|339863_340784_-|thioredoxin
MTIVEQDGGAAPQVPDLIKDTTTQSFVKDVIEESKRQPVLIDFWAPWCGPCKQLTPILEKAVKAAKGKVKLVKMNIDEHPAIPGQMGIQSIPAVIAFVGGRPADGFMGAVPESQVNAFIEKLTKGVPGAGEPDIAEIIKEAEAVLAEGDPAGAAQIYAEVLSIDAGNIPALAGLARCYVEAGAIDQARETLAQVPEAKRNDSAVSAVQAAIDLAEQAQSLGPIGDLEQKVAADPLDHQARFELATALNAAGKRKEATDQLLEIVKRDRKWNEDGARKQLVQFFEAWGGADEATVEGRKRLSTILFS
>NC_020453.1|WP_015663480.1|339126_339801_-|LON-peptidase-substrate-binding-domain-containing-protein
MPINAEYRGPAELPEIIPVFPLAGALLLPRGQMPLNIFEPRYLAMVDDSFRDGHRLIGMIQPDVTHSSSEDRPVLFKVGCVGRITQLAESGDGRYILELTGVSRFKVVEEMTVLTSYRQCKVDYFPFIDDFTARKGESAVDRDALLAVLTDFLKANNLKVDWAGIEAAPNEALVNALAMMSPYGPAEKQAMLEAPDLKTRAEILVAVTEMDLAKKRTSGDPPLQ
>NC_020453.1|WP_015663479.1|338295_339126_+|FTR1-family-protein
MLAALIIVFREVFEAGLIVGIVLAVTSAVPHRLRWIGAGLFAGLAGACVVAAFAGSLTQLFEGMGQELFNAAILTTAVVMLTWHNVWMARHGREMASELRTMGQAVAEGARPLVALATVIAIAVLREGSEVALFLYGVAAAGDGGGRALLGGGFIGLLLGVTVCLATYFGLMRIPPRALFRTTTVLITLLSAGMAAQAVFFLARANWLTTFDQVLWDSSAVLPERGVAGRTLKALIGYTDQPTAMQLMVYVGVIVATIALMRLTAMPPAPRIAAAE
>NC_020453.1|WP_083938780.1|337996_338284_+|cupredoxin-domain-containing-protein
MAAQVHAAGPNEICLTYANGQFEPKEPTVPADSPLTIRVKNMDAKAMEFESETLKIEKVVAANSEAVLNVRAMKSGRYEFYNDFNEKARGFINVQ
>NC_020453.1|WP_015663476.1|337185_337536_+|hypothetical-protein
MRDMLLLAAGLVAITVALIHGVLGETVVFARATISPERLRTLLRLVWQAGTVAWIGCGVLLIAAPWMGSEPARHWTVITVIVVFAFAACANALATRARHFGWVMLAGVVVLAAAGY
>NC_020453.1|WP_015663475.1|336553_337096_-|TetR/AcrR-family-transcriptional-regulator
MNEQLAAKDWLDLGLEVLASKGFTALKAEPLAKAMGVSRGSFYWHFADVAAYHAELLKHWREIAAEQIITGVEASAGPEPAIAVLLRRTFTIRLTLERAVRSWAASDPAARQAVQAIDKRRLGYVASQLTAEGLLPDIAQARAQVLYWAFLGHALAERPLPAERQQAVIDELIRFALHKP
>NC_020453.1|WP_015663487.1|347891_348473_+|cytochrome-c4
MRHGAAAASALALALMSISAQAADVEAGKAKAELCVGCHGENGISQTENIPSLAGQQDQFIQWQLVFFRAGTRKNEAMKPIIDQLNNEDIRNLGAYFASLQPAKSPPDDNPDLSKKGAEAAAGRRCASCHLDSYAGTKGVARVAGQREEYLVKALHDYKSGQRVGGSQAAMTDVAYPLSDEEITALAHYLAHL
>NC_020453.1|WP_015663488.1|348752_349676_-|2-dehydropantoate-2-reductase
MRILVVGAGAIGGYFGGRLLQSGADVTFLVRPRRAAELAGAGLVIRSPGGDVTLAGPPTVQADSLKQPFDVVLLSCKAFDLDDAINSFAPAVGPSTAIIPLLNGMKHLDVLDARFGRERVLGGLCAIAATLNEQREVVQLQPMQSLSFGERDGGSSERISAIFEIFQRGNFNASASDHVMQDMWEKWVFLASLAASTTLMRAPVGVILSAPGGKDFLLGMLDECSATAAAAGYAPAGAFFQRVSGMITAEGSPMTASMFRDLRAGLPVEADHVIGDLVARADAAKVPVPRLRIAYTQLKVYEAQRGK
>NC_020453.1|WP_015663489.1|349783_350521_-|SDR-family-oxidoreductase
MQQRNATVAVIGAGDYIGAEIVKKFASEGFTVFAGRRNGDKLAPLVAEVEAAGGRIVARSLDARNEAETTAFLNDADKHAPLEVVIFNVGANVNFPILETTDRVFRKVWEMACWAGFVAGREAARLMLPRGGGKIFFTGATASLRGGSGYAAFASAKFGLRAVAQSMARELMPQNIHVAHLIIDSGVDTAWVRERRAQIWGKEALDNPDLLMPPASVASAYWQLYQQPRTAWTFEMEIRPFGEKW
>NC_020453.1|WP_015663490.1|350576_351185_-|2-hydroxychromene-2-carboxylate-isomerase
MSRPAPEFMFDFGSPNAYLSHEAIPAIEKRIGVQFYYVPVLLGGIFKATNNKSPAESLAGIKNKREFHEVETQRFLKRYQVQPWVWNPHFPVNTLNLMRAAVAAQLEGVFEKYVDAAFHHMWREPKKMDDPEVAVAAITSSGLDGAKLFARAQEPEVKAKLVENTQRAVERGAFGSPTFFVGNEMFFGKEQLRDVEEMVLGK
>NC_020453.1|WP_015663491.1|351285_352638_-|MATE-family-efflux-transporter
MLVSTPAALRKPFLVFLAPMMLSNILQSLFGTINNVYLGQMIGVDALAAVSVFFPAMFFFISFVMGLGSGASVLIGQAWGAKEPAKVKAIAGTTLTVTLLLAGVIALGGLFSRELLTALATPANILDAAAGYARIMMITMPLTFAYILLSSQMRAVGDTVTPLAALAASTSLGLVLTPVFIRGWLGAPQLGVASAAWASAISTLMTLTLLHVYLRRRKHPLAFDAAFLRGMRPDPKLLRIVLRLGIPAAIGMIVMSLAEMVLIGLVNGFGSDATAAYGAVNQVLGYVQFPALSIAISVSIFGAQAIGRGNAEQIGRIVRTGIEMNVLLTGSLVAIGYLFSRTLMGFFITDPAVIEVAQRSLHIVLWSSVMFGMSTTFSAAMRASGTVWMPLAISAFAIAAIEVPTATWLSRSIGLDGVWIAYPVTFTAMMLLQMSYYLLVWRKRTVRRMI
>NC_020453.1|WP_144058221.1|352743_353316_-|DUF2239-family-protein
MDTYTAFAGQARIAAGALPKVALALKHGATAHAPVAIFSDRTGRPVDLDLRGSDREILARLVSEVPAAPDQQPSEPRGRGRPRLGVVAREVTLLPRHWEWLSAQPGGASVALRKLVDEARRTSGDKDRAREAREAAYHFMSAMGGNLPQFEEASRALFADDLRRFASLLVDWPADIRDHAVALAHRHRAD
>NC_020453.1|WP_015663493.1|353556_354222_+|glutathione-S-transferase
MLTVHHLNNSRSQRVLWLLEELGVPYEIIRYERQPDMRAPKELRAIHPLGKSPVITDGGNTVAESGAIVEYLIENYGNGRLIPPPKTPERLRYSYWLHYAEGSAMPLLLLKLLFNIMPKRAPALLRPLVRKVSNQALTTLVNPQLKQHMAFWESELQKSEWFAGEAFTAADIQMSFPLQAAASRGGLEHGHPRAMDFLARIEARPAYKIALEKGGPYEVGR
>NC_020453.1|WP_015663494.1|354225_355632_-|serine-hydrolase
MHLRRFVVGLLVFAALLVAGWLTYRPDRALRTATTTVAQMICAKTFVSGLDPHTVFAETMERPGLRRLRAVMRYRVEPDMGMVEASLLGLHASRASFHDGLGCVSSQGQKPPYVPHSDVAALRAAGPAPALPDFTEGAPVEPTDPALKAALDHAFEEPVGPPFRRTKAVVVVKDGRVIAERYAANIAVETPLMGFSMTKTVTNALLGILTRQGKLSPSIPAPVAEWREAGDPRHGITIEQLMRMTSGLALDETNSGFDPSSQMEIHRDMAAYAVHAPLIAPPGQRWAYSSASTQILARIIRDAAGGPEQTIELAWRELFNPLGMQHVTLQYDGTGTIQGYGSMLASARDWTKLGLLYLGDGVVGDRRILPEGWVAMSATATLDTDYGAGLWTNRSQHVHAQGRAKQGIPPDAFFAFGLLGQRLVIMPSQRMVVVRLGDAVDPDGDIRGVARLVREVIAATEAPATAAK
>NC_020453.1|WP_042340489.1|355799_357503_-|gamma-glutamyltransferase
MLLQAASLPARALDASGIDLLQPPGLAAPAQPPAHGMVVAQERIAAQVGQRVLELGGNAVDAAVATGFAMAVTYPVAGNIGGGGFMVVHLAASNEDIAIDYRETGPAAITRDIFLTDGKPDNAKSRDSALSIGVPGSVAGLALALEKYGSGKFTLAQLLHPAIVLARDGIPVADDVAVTLPMMAPRLAKWKSSAAIFIRPDGTVLKEGDRLVQRDLAATLTAIAEQGPRGFYEGPVADKLAKAIQDAGGIMTSADLKSYQPVLRTPVRGTYRGHDIVSMPLPSSGGTVLIEMLNILEGFPLAELKQGSPASLHLLIEAMKRAYADRARYLGDPAFVDAPVRAMLSKDYATRQRAGIDPAHATSAGDVLNIKPLREGSNTTHFSVVDNDGNAVSNTYTLNFPYGVGLVADGTGVLLNNELDDFTAAPGASNAFGLVGFEANLPGPGKRPLSSMSPTIVLKDGKPVLVTGSPGGSRIISTVLQVIVNVIDYQMDVRQAVGAPRLHHQWMPDEVRVEKGFADDVLAGLRARGHKIEEPMGRTSANSILVTSDGFVGAPDPRSKGATAAGR
>NC_020453.1|WP_015663496.1|357667_359059_+|MFS-transporter
MAVTTIETSGAADGRLYPGRTAVVSWIFFDWATQPYFTLITTFVFAPYFAAHVAPNAASGQALWGFATAAAGIVIALLSPVFGAIADATGRRKPWIAAFGAMLVIGSCLMWIGRPGAPDLIPPLLAAYVIATIGVEFATVFNNAMMPTLVPPERIGRLSGTGWATGYVGGIVSLIIVLGFLAANPDTGRTLFGVMPLFGLDPVTHEGDRISGPLTGLWFIAFVLPMFLFTPDYPARHRLGAAVREGIGQLRETLRSLPQQRDVALFLIANMIYTDGLVSLFAFGGIYAAGTFGWNTIQIGTFGIILAAAGTLGGWLGGKLDDLLGPKRVIAGSMTLLLLAIVGILMVNTDSILFIPVAPAMPGGPLFASLPERAYLVLGCIIGACGAPLQAASRSLLIRMVPRDRVAQYFGLFALTGKVTSFIGPLLIGIITAATASQKAGMAVLVLFFATGLLLLSQVRVRA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_020453_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_020453_2

2545715-2545821

Orphan

Consensus_repeat	Method
CCGTGAAGAACGGGGAGAGGGAGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_020453_2

>merge|NC_020453|2|2545715-2545821|CRISPRCasFinder
CCGTGAAGAACGGGGAGAGGGAGCGCACCGTCGTTGCGGCGGGAGCTCGTCTCCAATTTCTAGAGATGTCTGAATCTCGTAGCCGTAAGAACGGGGAGAGGGAGCGC

>NC_020453|2|2|2545715-2545821|CRISPRCasFinder
CCGTGAAGAACGGGGAGAGGGAGCGC	ACCGTCGTTGCGGCGGGAGCTCGTCTCCAATTTCTAGAGATGTCTGAATCTCGTA
GCCGTAAGAACGGGGAGAGGGAGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_020453.1\|WP_015665352.1\|2554341_2554905_-\|S-(hydroxymethyl)glutathione-synthase	unknown	unknown	gnl\|CDD\|235451
NC_020453.1\|WP_015665339.1\|2540376_2541144_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
NC_020453.1\|WP_015665348.1\|2549479_2550418_-\|acetamidase/formamidase-family-protein	unknown	unknown	gnl\|CDD\|225279
NC_020453.1\|WP_015665338.1\|2539612_2540380_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
NC_020453.1\|WP_015665353.1\|2554938_2556048_-\|S-(hydroxymethyl)glutathione-dehydrogenase/class-III-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|176260
NC_020453.1\|WP_015665335.1\|2535362_2537420_+\|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl\|CDD\|223223
NC_020453.1\|WP_015665337.1\|2538226_2539606_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|273816
NC_020453.1\|WP_015665344.1\|2544722_2545499_+\|cyclase-family-protein	unknown	unknown	gnl\|CDD\|377240
NC_020453.1\|WP_015665351.1\|2553516_2553969_-\|(2Fe-2S)-binding-protein	unknown	unknown	gnl\|CDD\|224991
NC_020453.1\|WP_015665354.1\|2556126_2556606_-\|c-type-cytochrome,-methanol-metabolism-related	unknown	unknown	gnl\|CDD\|163586
NC_020453.1\|WP_015665350.1\|2551165_2553514_-\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	unknown	unknown	gnl\|CDD\|224446
NC_020453.1\|WP_015665347.1\|2547998_2549471_+\|cytochrome-c-oxidase-accessory-protein-CcoG	unknown	unknown	gnl\|CDD\|274278
NC_020453.1\|WP_015665342.1\|2542643_2543582_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270370
NC_020453.1\|WP_160167593.1\|2550416_2551100_+\|transposase	unknown	unknown	gnl\|CDD\|366690
NC_020453.1\|WP_015665345.1\|2546641_2547436_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NC_020453.1\|WP_015665355.1\|2556738_2558541_-\|methanol/ethanol-family-PQQ-dependent-dehydrogenase	unknown	unknown	gnl\|CDD\|199836
NC_020453.1\|WP_015665336.1\|2537416_2538031_+\|cysteine-hydrolase	unknown	unknown	gnl\|CDD\|376404
NC_020453.1\|WP_015665340.1\|2541140_2541944_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224041
NC_020453.1\|WP_015665343.1\|2543680_2544670_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|376566
NC_020453.1\|WP_015665341.1\|2541945_2542644_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715

Protein	Function_ID	Function_description	E-value
NC_020453.1\|WP_015665352.1\|2554341_2554905_-\|S-(hydroxymethyl)glutathione-synthase	gnl\|CDD\|235451	PRK05417, PRK05417, glutathione-dependent formaldehyde-activating enzyme; Provisional.	2.10588e-138
NC_020453.1\|WP_015665339.1\|2540376_2541144_-\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	8.96291e-43
NC_020453.1\|WP_015665348.1\|2549479_2550418_-\|acetamidase/formamidase-family-protein	gnl\|CDD\|225279	COG2421, COG2421, Predicted acetamidase/formamidase [Energy production and conversion].	2.02608e-91
NC_020453.1\|WP_015665338.1\|2539612_2540380_-\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	1.02187e-47
NC_020453.1\|WP_015665353.1\|2554938_2556048_-\|S-(hydroxymethyl)glutathione-dehydrogenase/class-III-alcohol-dehydrogenase	gnl\|CDD\|176260	cd08300, alcohol_DH_class_III, class III alcohol dehydrogenases. Members identified as glutathione-dependent formaldehyde dehydrogenase(FDH), a member of the zinc dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. MDH family uses NAD(H) as a cofactor in the interconversion of alcohols and aldehydes or ketones. Like many zinc-dependent alcohol dehydrogenases (ADH) of the medium chain alcohol dehydrogenase/reductase family (MDR), these FDHs form dimers, with 4 zinc ions per dimer. The medium chain alcohol dehydrogenase family (MDR) have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding.	0
NC_020453.1\|WP_015665335.1\|2535362_2537420_+\|hydantoinase/oxoprolinase-family-protein	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	0
NC_020453.1\|WP_015665337.1\|2538226_2539606_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|273816	TIGR01813, Fumarate_reductase_flavoprotein_subunit, flavocytochrome c. This model describes a family of redox proteins related to the succinate dehydrogenases and fumarate reductases of E. coli, mitochondria, and other well-characterized systems. A member of this family from Shewanella frigidimarina NCIMB400 is characterized as a water-soluble periplasmic protein with four heme groups, a non-covalently bound FAD, and essentially unidirectional fumarate reductase activity. At least seven distinct members of this family are found in Shewanella oneidensis, a species able to use a wide variety of pathways for respiraton. [Energy metabolism, Electron transport].	5.60885e-67
NC_020453.1\|WP_015665344.1\|2544722_2545499_+\|cyclase-family-protein	gnl\|CDD\|377240	pfam04199, Cyclase, Putative cyclase. Proteins in this family are thought to be cyclase enzymes. They are found in proteins involved in antibiotic synthesis. However they are also found in organisms that do not make antibiotics pointing to a wider role for these proteins. The proteins contain a conserved motif HXGTHXDXPXH that is likely to form part of the active site.	2.1597e-41
NC_020453.1\|WP_015665351.1\|2553516_2553969_-\|(2Fe-2S)-binding-protein	gnl\|CDD\|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	1.70915e-69
NC_020453.1\|WP_015665354.1\|2556126_2556606_-\|c-type-cytochrome,-methanol-metabolism-related	gnl\|CDD\|163586	TIGR03874, 4cys_cytochr, c-type cytochrome, methanol metabolism-related. This family represents a c-type cytochrome related to (but excluding) cytochrome c-555 of Methylococcus capsulatus. Members contain four invariant Cys residues, including two from a heme-binding motif shared with c-555, and two others.	1.79921e-94
NC_020453.1\|WP_015665350.1\|2551165_2553514_-\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	gnl\|CDD\|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	5.14059e-79
NC_020453.1\|WP_015665347.1\|2547998_2549471_+\|cytochrome-c-oxidase-accessory-protein-CcoG	gnl\|CDD\|274278	TIGR02745, iron-sulfur_cluster-binding_protein, cytochrome c oxidase accessory protein FixG. Member of this ferredoxin-like protein family are found exclusively in species with an operon encoding the cbb3 type of cytochrome c oxidase (cco-cbb3), and near the cco-cbb3 operon in about half the cases. The cco-cbb3 is found in a variety of proteobacteria and almost nowhere else, and is associated with oxygen use under microaerobic conditions. Some (but not all) of these proteobacteria are also nitrogen-fixing, hence the gene symbol fixG. FixG was shown essential for functional cco-cbb3 expression in Bradyrhizobium japonicum.	1.62651e-160
NC_020453.1\|WP_015665342.1\|2542643_2543582_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270370	cd13652, PBP2_ThiY_THI5_like_1, Putative substrate binding domain of an ABC-type transporter similar to ThiY/THI5; the type 2 periplasmic binding protein fold. This subfamily is phylogenetically similar to ThiY, which is the periplasmic N-formyl-4-amino-5-(aminomethyl)-2-methylpyrimidine (FAMP) binding component of the ABC transport system (ThiXYZ). FAMP is imported into cell by the transporter, where it is then incorporated into the thiamin biosynthetic pathway. The closest structural homologs of ThiY are THI5, which is responsible for the synthesis of 4-amino-5-(hydroxymethyl)-2-methylpyrimidine phosphate (HMP-P) in the thiamin biosynthetic pathway of eukaryotes, and periplasmic binding proteins involved in alkanesulfonate/nitrate and bicarbonate transport. After binding the ligand, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ThiY/THI5 proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.99684e-41
NC_020453.1\|WP_160167593.1\|2550416_2551100_+\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	1.35644e-06
NC_020453.1\|WP_015665345.1\|2546641_2547436_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.70957e-75
NC_020453.1\|WP_015665355.1\|2556738_2558541_-\|methanol/ethanol-family-PQQ-dependent-dehydrogenase	gnl\|CDD\|199836	cd10278, PQQ_MDH, Large subunit of methanol dehydrogenase (moxF). Methanol dehydrogenase is a key enzyme in the utilization of C1 compounds as a source of energy and carbon by bacteria. It catalyzes the oxidation of methanol to formaldehyde, transfering two electrons per methanol to cytochrome c(L) as the acceptor. Methanol dehydrogenase belongs to a family of dehydrogenases with pyrroloquinoline quinone (PQQ) as cofactor, which also includes dehydrogenases specific to other alcohols and membrane-bound glucose dehydrogenases. This alignment model for the large subunit contains an 8-bladed beta-propeller; the functional enzyme forms a heterotetramer composed of two large and two small subunits.	0
NC_020453.1\|WP_015665336.1\|2537416_2538031_+\|cysteine-hydrolase	gnl\|CDD\|376404	pfam00857, Isochorismatase, Isochorismatase family. This family are hydrolase enzymes.	4.21045e-43
NC_020453.1\|WP_015665340.1\|2541140_2541944_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	1.00513e-111
NC_020453.1\|WP_015665343.1\|2543680_2544670_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|376566	pfam01557, FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase family. This family consists of fumarylacetoacetate (FAA) hydrolase, or fumarylacetoacetate hydrolase (FAH) and it also includes HHDD isomerase/OPET decarboxylase from E. coli strain W. FAA is the last enzyme in the tyrosine catabolic pathway, it hydrolyzes fumarylacetoacetate into fumarate and acetoacetate which then join the citric acid cycle. Mutations in FAA cause type I tyrosinemia in humans this is an inherited disorder mainly affecting the liver leading to liver cirrhosis, hepatocellular carcinoma, renal tubular damages and neurologic crises amongst other symptoms. The enzymatic defect causes the toxic accumulation of phenylalanine/tyrosine catabolites. The E. coli W enzyme HHDD isomerase/OPET decarboxylase contains two copies of this domain and functions in fourth and fifth steps of the homoprotocatechuate pathway; here it decarboxylates OPET to HHDD and isomerises this to OHED. The final products of this pathway are pyruvic acid and succinic semialdehyde. This family also includes various hydratases and 4-oxalocrotonate decarboxylases which are involved in the bacterial meta-cleavage pathways for degradation of aromatic compounds. 2-hydroxypentadienoic acid hydratase encoded by mhpD in E. coli is involved in the phenylpropionic acid pathway of E. coli and catalyzes the conversion of 2-hydroxy pentadienoate to 4-hydroxy-2-keto-pentanoate and uses a Mn2+ co-factor. OHED hydratase encoded by hpcG in E. coli is involved in the homoprotocatechuic acid (HPC) catabolism. XylI in P. putida is a 4-Oxalocrotonate decarboxylase.	7.38986e-71
NC_020453.1\|WP_015665341.1\|2541945_2542644_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	2.68854e-43

>NC_020453.1|WP_015665344.1|2544722_2545499_+|cyclase-family-protein
MARKLIDISVPLQNDVPADPPGNHPTITYIDHQQGLPRMLQFFDGLKAEDLPDGQGWAVEQVNLSTHNGTHLDAPWHFHPTMNRGERAWTIDEVPLEWCLQPGVKLDFRHFADGYVVTAKDVEDELKRIDHTLSPLEIVVVNTAAGARFGQANYVNSGCGMGYEATMYLLERGVRLTGTDGWSWDAPFVFTAQKYAETHDAALIWEGHKAGRHIGYCHLEKLHNLEQLPSTGFTVSCFPVKIERASAGWTRAVAIVDG
>NC_020453.1|WP_015665343.1|2543680_2544670_+|fumarylacetoacetate-hydrolase-family-protein
MKLATFRTEGGERIGVVHGGDTRLFDLAAAAERASAGNPAFVSMLSLIDAGEAALDDARALVERYGSDESLSYDVAATELLAPVPEPRQMRDGMSFPLHILQAPRGQRKLAARQRGDTDELARIDAEPLGELPEVYRKVPIFYITNRFSVRGPNTTVKWPRYSKVMDYELEFGVITKGRGKDIPATKASDHIFGFTIFNDFSARDTQRVEMDGRLGPSKGKSFDGGNVMGPWIVTPDEIGDPYRLKMEARVNGEVRSRGTSEGMLFPFEELIAYISKDETLMPGEFIGSGTVGNGCGLELGWYLEHGDVIELEVEKIGILKNKVERQDS
>NC_020453.1|WP_015665342.1|2542643_2543582_-|ABC-transporter-substrate-binding-protein
MRHRLRSAVVGLVLTTLALASATARAEKIQIGCTATSDCASAMVAVDEGIFKKHGLDAEMVLIGINSNIPAAILSNSIQIGGPTSTVFLQAADGGLDLVAVSGASIMNKTSNDAIAAFVRNGITINGPQDFKGKKVGAPGIGAFLQVLFVKWLVEKGVDPKSVNFVEVTFPTMADTIKSGGVDAVLTAEPFVMRMTNANLGTVGARYAAELARTEPIIFYAASREWAEKNPETVKKFRAAIAEAAPIVNNDREKASAAIAKFTKQPLELVKLTTPNSAEPVLKPEQLAWWVDVMSAQKMLQSKLDLKKLILD
>NC_020453.1|WP_015665341.1|2541945_2542644_-|GntR-family-transcriptional-regulator
MTASTPILQTEPASGDTLSERAAALIERDIVAGVLAPGSRLGIVELAKRYEIGPTPVREGLSRLVSRGLIVSIGQRGFRVAEVSRDDLVDITRLRTVVEKEALRLAMLNGSDQWEAGIIAALHQMRRYIQRMQTEFREGAPEFDQLHKAFHTALLGACGSRRLLAAHSDLYDQAYRYRRVMMRSFDDSSGFIREHEALADLVLARDATAAQSRLAAHLRSTVDIVYPEPKGA
>NC_020453.1|WP_015665340.1|2541140_2541944_-|ABC-transporter-ATP-binding-protein
MAEPALALVRSSPSPARAQIAFDNVSLVLGGKAIIDTISLDVAPGEILCVVGASGCGKTTALRLAAGLYQPTGGTVRFEGEAMRAPRREIAVVFQDYGKALLPWRTAAGNVSLALETIGMPSAQREARIAELLAKVGLAGHAAKYPTEMSGGMQQRLQIARCLAQDPKVLLMDEPFGALDAMTRQALQDEMLALVASTGATVVFVTHDLEEAIYLGDRVVGLLPHPGRIGLTMTIDLPRPRDQLATREHPEFLRLRRALFDFIEASE
>NC_020453.1|WP_015665339.1|2540376_2541144_-|ABC-transporter-permease
MTMPERIKPVLLPLTALLAFEAWMRLAGVQSDSLAPPSAIVLALMGALTDGSLLVATRDTLASAFAGFALGGAIGLVLGIALGLSHIFNRLMEVTIEAIRPIPSVALLPIALIALGFGYRMEIAIVGFACVWPVLIVTRAAVGSIEPRLIEVARVLRLTQLDRIRKIVIPAALPRIFLAFRLAAGIALIVAVTVEIAINPLGLGAGIMTAQQALRPDLMLAYLVWIGVTGFALNTALMAAQRSLFGRAAVMGEQA
>NC_020453.1|WP_015665338.1|2539612_2540380_-|ABC-transporter-permease
MRWSAIAWRVASFVVAAGEIALWQFAADQRLISPVFLPGPDRAWASLLRGFTSGDLLTKLTGTLTHMAYGWLLASVAGIALGAMIGSSRAMRIYVAPTLELLRPLPVSAIIPVAIAFLGLSQGMALFVIAFGSLWPLLLGTIHGFAAVEPRLYEVARVLHMSRLAVIFKIALPSAAPDILAGMRLSLTVALILAVVCEMLAGLDGLGQWVLLSARAFRSADLFAGVMLLGVIGYVTALTMGAAESHLLRWQAARR
>NC_020453.1|WP_015665337.1|2538226_2539606_+|FAD-dependent-oxidoreductase
MSAIEIIDRTPELAVDCLIIGAGAAGLVAALSASENGESGLVLERDAVPQGSTALSAGLIPAAGTRWQAALGIDDNPARFAADIMHKAHDEPDAAMVKLVTGTIGPTLEWLADRHQLPFSLVDNFSYPGHSRYRMHGLPSRAGRELIDRLRSAAESAGIDILCNAHATTLLLDRTQRIVGVRFTRPDGSSDEIGCRRLILACSGYGGNPALVARHIPEMAGATYFGHAGNQGDALTWGEQLGAATRHLGGHQGHGSVAHPARILISWASITEGGFQVNAMGHRFSNEASGYSEQAAHVLAQPDGIAWTIFDARIAGIAAQFEDFRSAVAHGAVLEADDVAGLAAVMRVPADALAATYDEVSEAKAQQRVDRFGRSFAGVPQLTPPYRAVKVTGALFHTQGGLVIDDRARVLRNDGRAIDNLFAAGGAACGVSGADASGYLSGNGLLTAVALGRVAGLAR
>NC_020453.1|WP_015665336.1|2537416_2538031_+|cysteine-hydrolase
MSDHKIPAAQSALLIVDLQNDFLDPKGAYGRAGQTAADIAALPPRLKPFADLMRARGGFVISTQFTLVPGKGGEPMISPHLKQLRPFLAKGDFLPGAWGHQLVDMLQPADVTIEKIAYSAFYMTRLEWVLRKCGIEKLYVAGIVTNGGVASTVRDAHIRDFETVVLEDGCAAFTAETHATAIAALKPVCRVASIAEVMKELAAV
>NC_020453.1|WP_015665335.1|2535362_2537420_+|hydantoinase/oxoprolinase-family-protein
MSRLGTIVGVDVGGTFTDLFYFDEAKRTFRTNKVPSNRGDEATGFLEGLQGFGAVSHLTSIVHGTTVGTNALLERKGARIGLITTRGFRDVLEMRRRDRRNTWGLWGDFVPVVERDMRAEVDERVLSDGTIRTAVDVAQVRATAQELLAKGAQALAIVFVNAFANPDNERRALEAVQSIWPNDNVACSSQILPEIREFERTSTTALNAYLQPVVGSYLQKLQNALAGEAFDGRFHIVQSNGGVMSTDAARRFPIRTALSGPAAGVIAAAEIAKAAGFPNVITGDLGGTSFDVSLVVDGATSLAAQTTIDFGLVVRTPMIEITTIGAGGGSIAHVDAGGLLQVGPESAGSRPGPVCYGGGNERPTLTDANVVLGRINAGRPIGGKLKALDVEAAKRAIAKHVGEPLRLGVMEAAEAIVRIADSKMAGAIRLMSIERGHDPARFAAVPFGGGGALHVSALIKDVGLKAALVPRYPGVTSALGCVIADIRHDQVQTLNMFVDGLDIAALMRWMLSEAEHAQGVVKDARLAIERVDTLFELDMHYVGQTHTIRATLPAEIRDGAIALTIDDVRRAFETAYQKSFSRLLPGVPIKIVNLRTAAIGVRPRFDLATLAPDATADLAKAKLGSRDVWFDGRWWDTAIYARLDLPVGSEIAGPAILEQPDATTVIAPGFNARVDKFGNVIVELI
>NC_020453.1|WP_015665345.1|2546641_2547436_+|fumarylacetoacetate-hydrolase-family-protein
MADTSRRNLLAAGSAAAAAAILTDARPAEAQTGPKPIFAIPAISIPIVGEPGVFPVRRIYCIGRNYAAHAIERGSDPNREPPFFFQKPTDAIQNVAVGEVVDHPYPSLTKNYHHEVELVAALKSGGTNIPAEQALDHVYGYALGLDMTRRDLQNGMAAEKKPWEIGKSFDHAAVLGPIHPVAKVGHFTKGAISLAVNGTVRQNSDLTKMIWSVAEQIAKLSEAFELKAGDIIYSGTPENVGPVVKGDVLLCKLEGLPDMSIKIV
>NC_020453.1|WP_015665347.1|2547998_2549471_+|cytochrome-c-oxidase-accessory-protein-CcoG
MAITIEIDHANTRRMAQGPGRSRSQAPARRSPQTAGGPVVPQGVKGPIRRLKWLILILTLAVYYVTPFVRWNRGPNAPGQAVLLDFAHGKLYLGPAEIWPQDLYLITAAMLLATFILVLVNALAGRLWCGFACPQTVWTDLFLLVERLVEGDRRQRLKNIGAPLTAKRIAQIVTKHALWMAIALGTGGTLIFYFTDAPELVRDVLHGEMSVTALTWTLVFAGTTYGLAGFAREQVCTFMCPWPRLQGAIWDPEAFTVNYRDYRGEVRMSAKKAVEARSQGLPAGDCVDCGACVAVCPIGIDIRQGPSFACINCGLCVDACDGVMAKLDRPRGLIDYESWRNIERGRVGEPRVSLLVRPKTIGLALACVALAAVIAVSFVTKTTAVLSVQHDRDPLAVRLSDGAVRNAYTVKLLNKSSAMQSFRLGISGVDAALAIVGHATADAIEVEPDGSETLRVTLTMPEPVDGDVTFQAVDPNGQVLLTARDRFINR
>NC_020453.1|WP_015665348.1|2549479_2550418_-|acetamidase/formamidase-family-protein
MSKRHEIPATHESMVWGYLDSTTPPVLEVGSGDTVTLHSFPAGGKETLPEDRSLVPPAYLTALDTMIQGPGPHFITGPVYVRGAQPGDTLQVDILDVKVSQDWGFVSILPLLGTLPDEFTEYETIHPKVDHDRQVCIMPWGTEIALDPFFGIVATAPPPAWGRCGSPVPRSFGGNMDNKELRPGTTLYLPVFNEGALFFAGDGHGVQGDGEVCITALETGVTGTFRLTVRKDMDITWPFAENATHLMSIGLDEDLDDAAKQAVREMVKHVCARTNLSRNQAYMLCSLAGNLRVTQLVDGNKGIHMLLPKAYL
>NC_020453.1|WP_160167593.1|2550416_2551100_+|transposase
MGWLRGTRSALISRQDIAAGNAKNWSALLTAPARLRRSGISCQFCQLASVSDLAATMQRQLGRRHPQHANGPCRREAEASRHYQAHGIHARIALMAVPGSLIMRRSLHTEHEILVLLGEAESGVPIAEICSTAGVSLRTFYRWRRRYGGLSSPALRHLKELEIGHQRLRALVTKLVEGRANAPPASVKAAPQLLRQDCGSTPHGGAGAPGQGRGAVIGRYASVRYGR
>NC_020453.1|WP_015665350.1|2551165_2553514_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit
MTIIANPAIANPAIAKSASRRGFERHLKVENVSRRAILQTLGLAGGFVLAAPLLSRPAFAAYETGAGKMPHGTVVDPKVFVSIAPDGIVSILAHRSEMGTGVRTSLPLIVAEEMEADWSRVRVVQAPGDEVKFGNQDTDGSRSTRHYLLPMRQIGAMARAMLEAAAAKRLGVPAGEVKAVNHEVVHSASGRRLGFGELAADAASLPVPAVDTIQLKSPKDFRYLGKGQVSIVDLHDITVGKARYGADVRLPGMKYAVIARPPVTGGKVKSFDPAEALKVPGVEQVIEVKGWPWPSKFQPLGGVAVIARNTGAAIKGRDVLKVEWEDGANGSYDSVAYRAELEAAARQPGLVVRQEGDVEAALKSADKVITGEYYLPHFAHASMEPPVAVADVKGDKAEIWAPVQSPGGTHEDVAKTLQIPPENVTVNVTLLGGGFGRKSKCDFALEAALLSKTLGAPVKVQWTRDDDLHHDFLHTVSVERIEAGLDKSGKVVAWRHRSVAPTILSTFAAGADHAAPFELGMGLVDMPFEIANIQCENPAVKAMTRIGWFRSVSNIPRAFAVQSMVGEIANATGRDQKDTLLDLIGSPRVLKLTSVKDLWNYGEPYESYPIDTGRLRRVVEFVAEKGNWGRSVPKGHGLGIAAHRSFVSYIATIVEVSVDDKGKLTVHQVDSAIDCGTFVNPERIQSQLEGAAIMGLSLAKYGEISFKNGRVQQRNFDDHPVVRIDEAPLITNVHIVPADADTPPSGVGEPGVPPFAPALANAIFAATGKRLRALPIGNQLAT
>NC_020453.1|WP_015665351.1|2553516_2553969_-|(2Fe-2S)-binding-protein
MIKLKINGQEQAWDGDPSLSLLWYLRDELGLTGSKYGCGAALCGACTVLVDKEAARACITAVSDVAGREVTTIEGLHPTGDHPVQKAWRQVNVPQCGFCQAGQIMQAAALLNQNPKPSHDQIRDAMAGNICRCGCYQRIENAVHLASTGV
>NC_020453.1|WP_015665352.1|2554341_2554905_-|S-(hydroxymethyl)glutathione-synthase
MTVHIHPSVDNGVKQGSGHFAGGTLVCKCHDRPVKVGITGDVAHNHACGCTKCWKPSGATFSVVAVVPRQNVTVLENGDKLKIVDPAAVIQRYACTGCGTHMYGRIENTGHPFYGLDFIHPELFQEQGSAAPGFAAFVSSVIESGVKPEQMGEIRARLKELGLEPYDCLSPALMDAIATHVAKAKAA
>NC_020453.1|WP_015665353.1|2554938_2556048_-|S-(hydroxymethyl)glutathione-dehydrogenase/class-III-alcohol-dehydrogenase
MKTRAAVAFEAKKPLEIVEVDLEGPKAGEVLVEIKATGICHTDAYTLDGFDSEGIFPSILGHEGAGIVREIGPGVTSVKPGDHVIPLYTPECRQCKSCLSRKTNLCTAIRATQGKGLMPDGTSRFSYKGQAIYHYMGCSTFSNFTVLPEIAVAKIREDAPFDKSCYIGCGVTTGVGAVVNTAKVTPGSNVIVFGLGGIGLNVLQGAKMAGADKIIGVDLNDSKEEWGRRFGMTHFVNPKKVTGDIVQHLVALTDGGADYTFDCTGNTTVMRQALEACHRGWGESIIIGVAEAGKEIATRPFQLVTGRVWKGTAFGGARGRTDVPKIVDWYMNGKIEIDPMITHTLKLEDINKGFDLMHEGKSIRSVVVF
>NC_020453.1|WP_015665354.1|2556126_2556606_-|c-type-cytochrome,-methanol-metabolism-related
MTVAENAWAEGPGDPAAVKSEDGKYFDKDGNPTYKVGADGSVDWYTYSGYRRYHSECHVCHGPDGMGSTYAPALRDSVKNMSYGDFLGVVASGRKNISTAQENVMPAFGDNPNVACYMDDLYIYLRARSNDAVGRVRPGKHEDKPPAYTEAENACMGKK
>NC_020453.1|WP_015665355.1|2556738_2558541_-|methanol/ethanol-family-PQQ-dependent-dehydrogenase
MRRVLLATCLTSVAALAAGGAWASEELVKMSANPKDWVMPAGDYANTRYSKLNQINAQNVGKLQVAWTFSTGVLRGHEGGPLIVGNMMYVHTPFPNKVYALDLSQDNKIVWRYEPKQDPNVIPVMCCDTVNRGVAYGDGKIFLHQADDKLVAIDAKTGAHVWTAVNGDPSKGQTGTSAPLVVKDKVLVGTSGGEFGVQCSMTAYDIKSGKQVWKAYSEGPDDQILFDANTTALGKPVGKDSSLKTWQGDQWKTGGGCTWGWVSYDPQLDMVYYGSGNPSTWNPKQRPGDNKWSMTVFARHADTGVAKWVYQMTPHDEWDYDGVNEMILSDQAINGQPRKLLTHFDRNGLGYTLDRTNGELLVAEKYDPKVNWTSGVDMDKNSATYGRPKVVDQYSTDKQGEDVNTKGICPAALGTKDEQPAAYSPDTQLFYVPTNHVCMDYEPFKVSYTAGQPYVGATLSMYPPAGETHMGNFIAWDGKTGKIAWSNKEPFSVWSGALATAGGVVFYGTLEGYLKAVDAKTGKELYKFKTPSGIIGNVTTYENGGKQYVAVLSGVGGWAGIGLAAGLTDPTAGLGAVGGYAALSNYTALGGALTVFSLPQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_020453_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_020453_3

6405893-6406134

Orphan

Consensus_repeat	Method
AGCGTGCCGTCATTGTCCGGATC	CRISPRCasFinder

3 spacers

The CRISPR arrays of NC_020453_3

>merge|NC_020453|3|6405893-6406134|CRISPRCasFinder
AGCGTGCCGTCATTGTCCGGATCGGCTGCTTTGAAGCGGCCGGCGACGAGCGCAAGGTACTCGTCCTTGGTCAGCGTGCCGTCATTGTCGGGATCAGCCGCCTTGAGGTCCTTCGCCGAGACGCGGCCGCGCAACTCCTTGGCGTCGAGCGTGCCGTCATGGTCGCGATCGAGCTTGTCGAACAGCGCGCCGGCTGCAGCCCGGACCTCGTTCATATCGGCGGTGCCATCCTTGTCAGGGTC

>NC_020453|3|3|6405893-6406134|CRISPRCasFinder
AGCGTGCCGTCATTGTCCGGATC	GGCTGCTTTGAAGCGGCCGGCGACGAGCGCAAGGTACTCGTCCTTGGTC
AGCGTGCCGTCATTGTCGGGATC	AGCCGCCTTGAGGTCCTTCGCCGAGACGCGGCCGCGCAACTCCTTGGCGTCG
AGCGTGCCGTCATGGTCGCGATC	GAGCTTGTCGAACAGCGCGCCGGCTGCAGCCCGGACCTCGTTCATATCG
GCGGTGCCATCCTTGTCAGGGTC

Protein	Signature genes	Signature genes Name	Protein_function
NC_020453.1\|WP_015668703.1\|6407201_6408044_+\|hypothetical-protein	unknown	unknown	unknown
NC_020453.1\|WP_015668700.1\|6405120_6405756_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NC_020453.1\|WP_144058556.1\|6412710_6414453_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|224567
NC_020453.1\|WP_015668693.1\|6392943_6393927_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NC_020453.1\|WP_015668691.1\|6391370_6391955_+\|hypothetical-protein	unknown	unknown	unknown
NC_020453.1\|WP_042340264.1\|6406427_6406871_-\|hypothetical-protein	unknown	unknown	unknown
NC_020453.1\|WP_015668692.1\|6391996_6392947_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NC_020453.1\|WP_015668705.1\|6408457_6409360_-\|energy-transducer-TonB	unknown	unknown	gnl\|CDD\|223880
NC_020453.1\|WP_015668711.1\|6414594_6414921_-\|DUF2160-domain-containing-protein	unknown	unknown	gnl\|CDD\|378313
NC_020453.1\|WP_015668709.1\|6411719_6412433_-\|hypothetical-protein	unknown	unknown	unknown
NC_020453.1\|WP_042340262.1\|6396752_6397850_+\|alkene-reductase	unknown	unknown	gnl\|CDD\|239243
NC_020453.1\|WP_015668694.1\|6393931_6395416_-\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NC_020453.1\|WP_042340263.1\|6398953_6402034_-\|autotransporter-outer-membrane-beta-barrel-domain-containing-protein	unknown	unknown	gnl\|CDD\|377133
NC_020453.1\|WP_015668695.1\|6395455_6396478_-\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380652
NC_020453.1\|WP_015668704.1\|6408096_6408438_+\|hypothetical-protein	unknown	unknown	unknown
NC_020453.1\|WP_015668707.1\|6409785_6410562_-\|tonB-system-energizer-ExbB	unknown	unknown	gnl\|CDD\|131844
NC_020453.1\|WP_042340971.1\|6398036_6398408_-\|hypothetical-protein	unknown	unknown	unknown
NC_020453.1\|WP_015668699.1\|6402430_6404809_-\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657
NC_020453.1\|WP_015668706.1\|6409356_6409782_-\|TonB-system-transport-protein-ExbD	unknown	unknown	gnl\|CDD\|183064
NC_020453.1\|WP_015668708.1\|6410921_6411731_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274350

Protein	Function_ID	Function_description	E-value
NC_020453.1\|WP_015668700.1\|6405120_6405756_+\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	8.35899e-46
NC_020453.1\|WP_144058556.1\|6412710_6414453_-\|extracellular-solute-binding-protein	gnl\|CDD\|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	5.30451e-24
NC_020453.1\|WP_015668693.1\|6392943_6393927_-\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	9.03114e-50
NC_020453.1\|WP_015668694.1\|6393931_6395416_-\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	1.22017e-170
NC_020453.1\|WP_015668692.1\|6391996_6392947_-\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	7.3322e-58
NC_020453.1\|WP_015668705.1\|6408457_6409360_-\|energy-transducer-TonB	gnl\|CDD\|223880	COG0810, TonB, Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane].	1.49355e-14
NC_020453.1\|WP_015668711.1\|6414594_6414921_-\|DUF2160-domain-containing-protein	gnl\|CDD\|378313	pfam09928, DUF2160, Predicted small integral membrane protein (DUF2160). The members of this family of hypothetical prokaryotic proteins have no known function. It is thought that they are transmembrane proteins, but their function has not been inferred yet.	2.16676e-33
NC_020453.1\|WP_042340262.1\|6396752_6397850_+\|alkene-reductase	gnl\|CDD\|239243	cd02933, OYE_like_FMN, Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Members of OYE family include 12-oxophytodienoate reductase, pentaerythritol tetranitrate reductase, morphinone reductase, and related enzymes.	0
NC_020453.1\|WP_042340263.1\|6398953_6402034_-\|autotransporter-outer-membrane-beta-barrel-domain-containing-protein	gnl\|CDD\|377133	pfam03797, Autotransporter, Autotransporter beta-domain. Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.	1.08146e-34
NC_020453.1\|WP_015668695.1\|6395455_6396478_-\|substrate-binding-domain-containing-protein	gnl\|CDD\|380652	cd19997, PBP1_ABC_sugar_binding-like, monosaccharide ABC transporter substrate binding protein such as CUT2. Periplasmic sugar-binding component of uncharacterized ABC-type transport systems that are members of the pentose/hexose sugar-binding protein family of the type 1 periplasmic binding protein superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes transition from an open to a closed conformational state upon ligand binding. Members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes; however their substrate specificity is not known in detail.	3.82832e-130
NC_020453.1\|WP_015668707.1\|6409785_6410562_-\|tonB-system-energizer-ExbB	gnl\|CDD\|131844	TIGR02797, Biopolymer_transport_protein_ExbB, tonB-system energizer ExbB. This model describes ExbB proteins, part of the MotA/TolQ/ExbB protein family. The paired proteins MotA and MotB, TolQ and TolR, and ExbB and ExbD harness the proton-motive force to drive the flagellar motor, energize the Tol-Pal system, or energize TonB, respectively. Tol-Pal and TonB are both active at the outer membrane. Genomes may have many different TonB-dependent receptors, of which many of those characterized are involved in siderophore transport across the outer membrane. [Transport and binding proteins, Cations and iron carrying compounds].	1.09626e-89
NC_020453.1\|WP_015668699.1\|6402430_6404809_-\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	3.77707e-41
NC_020453.1\|WP_015668706.1\|6409356_6409782_-\|TonB-system-transport-protein-ExbD	gnl\|CDD\|183064	PRK11267, PRK11267, biopolymer transport protein ExbD; Provisional.	7.38905e-57
NC_020453.1\|WP_015668708.1\|6410921_6411731_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	1.374e-10

>NC_020453.1|WP_015668700.1|6405120_6405756_+|response-regulator-transcription-factor
MYRVLLVDDHPVVITACRWLLNEAGIATLIEAHDAESGYDAFVRDRPDAAVIDLRLQGDEFGGIRLIERMRSHDPRARILVFSMLTDPRIVRSAIDAGASGYLLKDAPPHELPKALEQVRTGGTYLAPELATRIALLRNESDGNLPTSLTPRERQALALLAEAKSYQAIADQLGISYKTVINLTYRLRQKLGARSLPDLVRLAVEMARPGL
>NC_020453.1|WP_015668699.1|6402430_6404809_-|TonB-dependent-receptor
MTRLSALKSALLATCALLPTAAFAQQTLQTIEVVGVSPVQGSEIAKDKIPSNVETIGARELDHSRAPSLLDGILQSVPGVSLSDQTGNAFQRDLNYRGQTASPVLGTPQGIAVYQNGTRINEAFGDVVNWDLIPEMAIARMTLMPNNPLFGLNATGGALSIEMKNGFTYQGAETQLFGGSFGRLQSGAQYGWNNGTYSAYIAAEGAYDRGWRDYSSASQIRRMYADFGARGDTAEFHLSFTGADNKLGSVAATPIEMLNQRWSSVYTWPQSLRLQMQMVQASLKWAPTDTLSVQANGYYRNYKSSRIDGNGTEVQDDGGGFFVLQDAAGTPWGINRNGPVANTLAGDAALGQIDRNTVKTDSYGGSLQATSTTQLFGHDNHFVVGASVDHGNTNFQATSELGTIDNNLFVTGLGVYIDQPNAGLAPVNLNAKNTYLGVYATNTFDITSQLALTAGGRFNWAQINLRDQTGFAPLLNSDNNFQRFNPVVGLTYKITPNMTAYAGYSEANRAPTPLELGCSDPANPCLIDNFLIADPPLKQVVSRTVEGGLRGEISGGGSAYAAAPPPYRKAPVKAAAVDDGWRLRWGLSLFRTENSDDIIQVVDPANPVRGYFKNAGNTLRQGVEAKLDLAWNRWTAYANYTFIDATFRSAFDVNDPFLGVPVGVVSGNHIPGIPAHRLKLGAEYAVTDDWKVGASVNYVGSQYLLHDETNVYPKVPAYWVVNVNTSYQVTKNVEVFGLVQNLFNQRYYSAGTVFDPAGFNTAGGGTAFALNDPRSMVPGMPLAAYAGIRAKF
>NC_020453.1|WP_042340263.1|6398953_6402034_-|autotransporter-outer-membrane-beta-barrel-domain-containing-protein
MKSKNRKRSEAAAASVVLLSTWMVTGEARAECTTPGLTVTCSGSITSAVAVYDAAAGTATPSSGSNSYTPANPAFPATGYNPNPPTTIVTLDSTAVRNLTTNTQAGLADRGMIAANFSNAEDPAVNNVVINNAGWLSLTTSQLSAGRLHVIVADSQVNRFTVNNTGTLAVAQNFFGTFDSTKLSVSIGATATGRYNGTNLAIISALYSDDNTNSFVVNNRAGGTISATGNYAAAYYGRADTTITNSGTIANTSWTAASRFSDGHWAVGAFAGAEFDTIPGSNPDSPLYKFDASGNVTVTETKALTLTNNAGGVIKGDILALDTNPLTTAAGLAAGSSFPLTGSGSNSGPRDSIVANAGLIQGNIYLGSGQHDVSNNGTIAGSISVDQSASRGSFAKATAGTVAGTYSSSGSGTDANGNACPTAGANTTDPLCAASTNQAATFFGARTFNLVNTGTLGGDITINDQDGATNTILLKGAGFSGNVVAQNGLGSNSLTLDGVTSLASIVNFGMLDLMKSQVTVSGGAGVQLVDGAVLRTTIFGPGGTAAAPSTRIGNITGTVTFAGAGTVAPTLQGIVRNGDVYRIATSVSATPLDVDFASALVGFTADTSTGALLLNASVRSPATIAGISPSSLAALNGLFGYNGSSAQVQALGGAVQSLGTDREVRNAGDQLRPFVNGAQVQVPLSTASLFQNQIDNRLTAAAASPNSRVASAFADDTDPLTSMLMAFNSTKARPTVKAPLAPAIAPEPERTVWGSLIGTNTSQHDVAGVAGYSGNTGGLVAGIDQRIDSAFRVGAAFGYATSAMDDRTAAGDAVGMQHYQGTVYGAYAQPSWYVNGSAGIALVDYTTTRRINFAGFTDTVSGSHKGWLTLARGEFGMPVKVDRAVLTPFAGVTYGRLDQQAYTEASAAGAALTIAKQTTNSVRSNLGLRSTVPLLVTSTYGFGLETLAAWRHEFGNTAQNVTAAFAGGGATFFAAGPSPERNLAELGAALKLVAFGERQSVSLGYNAVMGSQYLEQSAVLKVRAEF
>NC_020453.1|WP_042340971.1|6398036_6398408_-|hypothetical-protein
MISVVTLAGGLGAHSLLLGDATARDLDGRYANSPLKGWFENLRSRKGPCCSDADGTALSDIDWDMKDGRYRVRIEGQWWTVPEEAVVTEPNRAGRTMVWPVYYRELNTGLRIDVRCFLPGSMT
>NC_020453.1|WP_042340262.1|6396752_6397850_+|alkene-reductase
MSTSKLFEPYKLGPITLANRVVMAPLTRNRAVEGLVPSPLATEYYGQRASAGLLITEASQVSQQGQGYQDTPGIYSKEQIAGWREVTDAVHAKGGRIFIQLWHVGRISHVSLQPNGGAPVAPSAIAAKTKTFVGGTFTDVSTPRALEPSEIPGIVEAFRQAALNAIEAGFDGVEIHGANGYLLDQFAKDGANKRTDAYGGSIENRARLMLEVAKAVSGAIGADKTGIRLSPVTPANDISDSNPQALFDYIVDRLAALNLVFIHVIEGATGGPRDNAPFDYASLRKRFKGAYIANNGYDLALANKVLDADAADLIAFGKLFIANPDLVERLKTGAPLNELDRATLYGGGEKGYTDYPTLKAAQAAE
>NC_020453.1|WP_015668695.1|6395455_6396478_-|substrate-binding-domain-containing-protein
MKSGIGIAAVCAAVSIIVGGSAHADTSGKKIAFSNNYAGNSWRQAMLKSYEIVTKKAVTDKVVAAADIFTTADKEVPTQAAQIQNLILQGYDAIVINASSPDALNGAVKQACSAGIIVVSFDGVVTEPCAYRVVVDFKAMGMQEVEQMAKFQPKGGNLLEIRGLAGTSIDDAIHAGILEGVKAHPQFKIVGSVTGDWDQTTAQKAVATVLPSLPEIVGVVDQGGDGYGAAQAFAAAGKPRPTIIMGNRQDELQWWKEQKAKDGYTTWSASIAPGVSTLAFWVAQQVLDGNKNIPHDLLVPYLAFTQDNFEAELPNIPKGSVASHEYTQAEAIAAIKANMK
>NC_020453.1|WP_015668694.1|6393931_6395416_-|sugar-ABC-transporter-ATP-binding-protein
MTVTCPELVRLDGIEKHFGAVRALGGVDLALASGECLGLVGHNGAGKSTLMHILAGTAAADRGHLAIGGVKPVGYSPDLAKELGVRCVFQELSLCPNLTVAENARVFHPSLTGFAWRRKAGRLILDKLDAIFPGHGIAASDLVEDLPIGRRQMVEVARAFTVTDQPVRLVILDEPTSSLDAHTSGQLLGFMRRVIAEGVSCIFISHVLGEVLANCDRIVVMRDGRTVADAPATAFDRDSLVGAMGDVEAHMRDAAASHGQARGRSPLRVRARLKRQNRAQDPVVQELVAHEGEVIGLAGLAGHGQTELLLTVFAAATGTVSGVEVMASVALVAGDRQSDGVFPLWSIAENIGVRSLSRLRRGLLISPAREHALAMEWRDRIGIRTPDVHNNILSLSGGNQQKVLFARALGSDARIVLMDDPMRGVDVGTKLEVYALIRAEADNGRTFLWYTTETDELKQCDHVYVFRNDAIVADLTRDELTEQKVIQSSFAEAG
>NC_020453.1|WP_015668693.1|6392943_6393927_-|ABC-transporter-permease
MASLNAVAKQALPMLGARNLPRLLRALLPALSLALVLIGIAWLNPRAISYFGFTLMLNLAVPIALATVAQMFVIAGNDLDLSIGAFVGFVGCVTATWLRETPLLGIVTLLGCIAAYAGLGALIHLRNLPSIVVTLGMSFVWQGLAILMLPKPGGKAPDWLLTIMAVKPPFVPFPVLAAALIAVVAHVGLMRTSYGAVLRGCGGNSLAISRAGWSLLKAKMTLFACTGLFGVLSGLALIGTTTSGDANIGNGYTLLSIAGVILGGGEFVGGRVSPIGAVIGALTLALAASPLLTFMRIPPDWQVAANGAILIVVLAARVLISRKDAAR
>NC_020453.1|WP_015668692.1|6391996_6392947_-|ABC-transporter-permease
MKVALGSTFAKPWIWSFIGALAVWLAAIVFTGGYGAGGMLSAALSLAVFTVVVGVGQMFVITLGPGNVDLSLPANIGLASAVAMTVMAGDDQRIALGLLAALACGAAVGTANYLLIWALRIPPIIATLSASFVIQSIDISYGRGLQIKPPPGFAEFTNIQLFGIPLLAMLTVLFMIGANVVLQRTVFGRSVLAIGQNMRAARLAGIPVNRVRFATYVLSGTLGGIDGALLAGYFRGANVDIGNEYLLASIAVVVIGGTSVAGGKANIPGLFGAALFLVLLLTMLNTFGVSAGVRLVLTGLVIVAVITAASGAETAR
>NC_020453.1|WP_015668691.1|6391370_6391955_+|hypothetical-protein
MNKRKSKKARIIPTAMPDLARSTETAERTVLAADLAGREGEQLHARLETETRLSELLGQETEAKLPPIPPSELDVRPALLLQPAHPSSGVTPPIEAPADVKESAHTMGEARTNDRLLESDGPRPAIAGLEACQALLTEIARDNLDFAARLASMRSPLEIVGIATEFASSQIGTYGRFSKAVADIASGRPVRWPD
>NC_020453.1|WP_042340264.1|6406427_6406871_-|hypothetical-protein
MCNLPCGSWISQRSDAPVTRANDHRHRTAARFAALAVMFSVALCALMALATPSFARDRLQREELEAWWNETQAGKSATRKTCAVAAETGCSRDKVARSRGAAYPIVKRARNVTANARAEARQSADSDAARTPRHDRPGRYFLHGPRF
>NC_020453.1|WP_015668703.1|6407201_6408044_+|hypothetical-protein
MAAGAFLLAPFGAAAEEIQGNDPASPGHFQVEQRFGYLTTFNPQQNGGRRVPQRAVTGETEIGYSPTEWYEIALTSPYAFARTNVPMALGNVMDNGVPGYSFQSGGVTIRQTFIQGDRLERTVFVGLVSRTILAPQGGLTPDLWVANKAGAGQPGAPRFVQEATPRVAQMFTPIIGVNLPNDYQLIFNANMTFGIDGAGSAFEPSVRFVKRLSDRWTVGIEHFSNLGPFGYILPWNQQMQTLYAVADTKFKGFEFSFGVGYGLTNASRGLALKTSIGKDF
>NC_020453.1|WP_015668704.1|6408096_6408438_+|hypothetical-protein
MRRLVTACAVLLLAGSAASAEDGPRFLNRTGQTIVKMYLAAAGTKNWGVDQCKNDDEGMVDHNERMTLVGVKSGRYDIKLSEQGGRTCLAKNIELKEGAQFVVRDTDLTECSK
>NC_020453.1|WP_015668705.1|6408457_6409360_-|energy-transducer-TonB
MSVLTLDPFDQEERRERTLWTVAALLVAGLHVGLAVGYLLLRPAPEGRAEAPAFDVVFTPAVVSEPAPAIQDAPPAEPTPPVEPPKEEPVKDEPAVREAVAEPVPEVMLSPEPAPQVTLAPEPPRADDVVLPPPTPPKPIEAKPPEAKPAPVPERVEHKPAEKKEAKERAEKKPAPAKPAAAPASRPSRVASAPNPGEDSVGAREGQAAWNHQVEAQIGRAAAGAYPSDGNGVTGTVAISVVIDRNGRLLSRRLAGSSGSPALDRAALSIIERAQPFPRFPPVMTMAQVSRTVPLRLRPR
>NC_020453.1|WP_015668706.1|6409356_6409782_-|TonB-system-transport-protein-ExbD
MAVKLARRTDEFEETHDINVTPFIDVMLVLLIIFMVAAPLATVDIPVNLPAISAEPQPRAETPIFVTFKADRSLAVGDHSVEQADIAASLDAATRSDHGQRVLLRADQTLPYGEVMALMNTLRRAGYVKVALVALEDRGAQ
>NC_020453.1|WP_015668707.1|6409785_6410562_-|tonB-system-energizer-ExbB
MDQANIASLVSPLPEALSPWTMFMKADIVVQAVMIGLVLASVATWTVLVVKTIQLRSALRKGRGALSITVAARSLSDATGRVSAEDGVVGRLLATAEDEIDKSRGLPADGIKERVSWQFERIEAAAVARIGRGIGILATVGAVAPFVGLFGTVWGIMNSFIGISHAHTTNLAVVAPGIAEALLATAFGLAAAIPAVVIYNLFARATGGYRAVIADASVAVMRLISRDLDRQHAGPAEARRSAIRAVDAPLLSIANPAE
>NC_020453.1|WP_015668708.1|6410921_6411731_+|tetratricopeptide-repeat-protein
MTSTPEDIVRRAAASYNAGHIDEARRLCEQELARSPGEPMLSHLLAAVLLSRQEIAAARSHVAASLARRPDNAAAQLLAARIARADKDYAAALDHVDRALALAPQREAFVEKARILDQAGHRAQARSAWQAILKVVPDHGEAAARLGRFAFEESDLAGAASYLEQATSGDAPASVWFDLGLVRQDRRDHSGAAVAYRKALALNPGHAEAALNLGIALQESGDADAAMPFYRTAYRLRPQMFGAIAMALTSAAHGKLWLDEAALRLALAR
>NC_020453.1|WP_015668709.1|6411719_6412433_-|hypothetical-protein
MRMTFRCDPALEPHLPRPVPARTTLPDWLRRMPASAHSDLHGRDIRTVKQCPPFVDAMAHGVMILLPCDIQVERGAFSWDWDIPAPATAGHPRAPLSFHVAAQFEGAPFAHDRQSAIKFNSFWTIECPEGWSLFATHPVNRDDLPFRTVTGLVDADRFHDGGINFPALWIAPDYCGVVPKGTPVAQCFPVPREALELVYEPFDADHGIAYSETVAQVLAAPNVYRKRFRARRGRLTS
>NC_020453.1|WP_144058556.1|6412710_6414453_-|extracellular-solute-binding-protein
MTSAFALMAASAAITAPAYADEAAAKKWIDSEFQPSTLSKDDQLKEMQWFIKAAAPFKGMDINVVSETLTTHEYESKTLAKAFEEITGIKVKHDIIQEGDVVEKIQTQMQSGKNVYDGWINDSDFIGTHFRYGQAVDLTEWMAGEAKDVTNPGLDVNDFIGKSFTTAPNGHLYQLPDQQFANLYWFRYDWFTNPDYKAKFKAKYGYDLGVPVNWSAYEDIADFFTNDIKEINGAKVYGHMDYGKKDPSLGWRFTDAWLSMAGNGDKGIPNGLPVDEWGIRMEGCRPVGSSVERGGDVNGPAAVYSIAKYLDWMKKYAPPQAQGMTFSESGPVPSQGNVAQQIFWYTAFTADMVKPGLPVMNADGTPKWRMAPSPHGSYWKEGMKLGYQDVGSLTLLKSTPVDRRKAAWLYQQFIVSKTVSLKKSHVGLTFIRESDIWDKSFTERAPKLGGLIEFYRSPARVQWTPTGNNVPDYPKLAQLWWQNIGDASSGAKTPQQAMDALAAAQDSVLERLEKSKVQGDCGPKLNKKETAEYWFAKSAKDGNIAPQRKLANEKPKGETIDYDTLIKSWPASPPKRAEAK
>NC_020453.1|WP_015668711.1|6414594_6414921_-|DUF2160-domain-containing-protein
MDNIAWMAWTLPTAIFFVALGGTLAVMTWLAARYPEAERVGILRIPTTRGDRLFVSLISAAVIHLAWIGFVGTDPLTTLPIGEGLELSSLWLATVISLASAVAIFRTV

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1891277 : 1945955

Rhizobium_phage(10.0%)

tail,portal,head,capsid,integrase,terminase,plate

attL 1884266:1884280|attR 1893765:1893779

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1884266:1884280	attL	NA	NA	NA	NA
WP_015664766.1\|1891277_1892459_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_015664767.1\|1892751_1892955_-	hypothetical protein	NA	NA	NA	NA
WP_144058277.1\|1892941_1893391_-	hypothetical protein	NA	NA	NA	NA
WP_015664769.1\|1893428_1894583_-	DNA-directed DNA polymerase	NA	NA	NA	NA
1893765:1893779	attR	NA	NA	NA	NA
WP_144058278.1\|1894682_1895366_-	hypothetical protein	NA	NA	NA	NA
WP_144058490.1\|1895724_1896021_+	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015664772.1\|1896033_1896810_+	ATP-binding protein	B4UTW5	Rhizobium_phage	8.3e-45	39.6
WP_015664773.1\|1896851_1897478_+	hypothetical protein	NA	NA	NA	NA
WP_015664774.1\|1897589_1898714_+	hypothetical protein	B4UTX3	Rhizobium_phage	1.9e-74	45.3
WP_144058279.1\|1898787_1898985_+	hypothetical protein	NA	NA	NA	NA
WP_015664776.1\|1898984_1900928_+	DEAD/DEAH box helicase	A0A2H4GY70	Pseudomonas_phage	2.7e-116	41.3
WP_015664777.1\|1900940_1901207_+	hypothetical protein	NA	NA	NA	NA
WP_144058280.1\|1901340_1901544_+	hypothetical protein	NA	NA	NA	NA
WP_015664779.1\|1901555_1904063_+	bifunctional DNA primase/polymerase	NA	NA	NA	NA
WP_042338973.1\|1904309_1906262_-	ATP-binding protein	NA	NA	NA	NA
WP_015664782.1\|1906650_1907049_-	hypothetical protein	NA	NA	NA	NA
WP_015664783.1\|1907251_1907734_-	transglycosylase SLT domain-containing protein	A0A1P8CWQ1	Bacillus_phage	5.6e-07	39.0
WP_015664784.1\|1907745_1908093_-	HNH endonuclease	A0A291AUJ4	Sinorhizobium_phage	2.3e-31	57.8
WP_015664785.1\|1908089_1908317_-	hypothetical protein	NA	NA	NA	NA
WP_015664786.1\|1908319_1908559_-	hypothetical protein	NA	NA	NA	NA
WP_015664787.1\|1908570_1908981_-	hypothetical protein	NA	NA	NA	NA
WP_144058281.1\|1909436_1910291_+	hypothetical protein	NA	NA	NA	NA
WP_015664789.1\|1910313_1911300_-	hypothetical protein	NA	NA	NA	NA
WP_144058282.1\|1911377_1911812_+	hypothetical protein	NA	NA	NA	NA
WP_015664791.1\|1911811_1912462_+	hypothetical protein	NA	NA	NA	NA
WP_042338979.1\|1912687_1913599_+	hypothetical protein	NA	NA	NA	NA
WP_015664793.1\|1914911_1915178_-	hypothetical protein	NA	NA	NA	NA
WP_015664795.1\|1915696_1916257_-	antirestriction protein ArdA	G9FHQ1	Rhodococcus_virus	9.4e-14	33.3
WP_015664796.1\|1916273_1916507_-	hypothetical protein	NA	NA	NA	NA
WP_015664797.1\|1916510_1917206_-	hypothetical protein	NA	NA	NA	NA
WP_015664798.1\|1917962_1918562_+	deoxynucleotide monophosphate kinase	A0A0K1LM89	Caulobacter_phage	3.7e-16	37.3
WP_015664799.1\|1918565_1919138_+\|terminase	terminase small subunit	NA	NA	NA	NA
WP_015664801.1\|1919305_1921252_+\|terminase	phage terminase large subunit family protein	A0A0C5ABH4	Bacteriophage	2.9e-139	46.1
WP_015664802.1\|1921255_1921486_+	hypothetical protein	NA	NA	NA	NA
WP_160167589.1\|1921675_1922890_-	hypothetical protein	NA	NA	NA	NA
WP_015664804.1\|1923264_1923471_+	hypothetical protein	NA	NA	NA	NA
WP_015664805.1\|1923470_1925090_+\|portal	phage portal protein	G8DH43	Emiliania_huxleyi_virus	6.1e-90	38.9
WP_015664806.1\|1925086_1926382_+	S49 family peptidase	A0A219YAK4	Aeromonas_phage	1.4e-41	34.2
WP_015664807.1\|1926394_1926757_+\|head	head decoration protein	NA	NA	NA	NA
WP_015664808.1\|1926795_1927854_+\|capsid	major capsid protein	A0A2D1GMR5	Marinobacter_phage	5.8e-49	35.9
WP_015664809.1\|1927857_1928298_+	hypothetical protein	NA	NA	NA	NA
WP_015664810.1\|1928297_1928648_+	hypothetical protein	NA	NA	NA	NA
WP_015664811.1\|1928649_1929177_+	hypothetical protein	NA	NA	NA	NA
WP_015664812.1\|1929178_1929889_+\|plate	phage baseplate assembly protein V	NA	NA	NA	NA
WP_015664813.1\|1929943_1930357_+\|plate	phage-related baseplate assembly protein	A0A193GYY8	Enterobacter_phage	8.4e-12	38.2
WP_015664814.1\|1930356_1931217_+\|plate	baseplate J/gp47 family protein	Q6K1H4	Salmonella_virus	9.9e-23	30.6
WP_015664815.1\|1931216_1932062_+	hypothetical protein	NA	NA	NA	NA
WP_015664816.1\|1932045_1932744_+	hypothetical protein	NA	NA	NA	NA
WP_015664817.1\|1932743_1935962_+	DUF4815 domain-containing protein	K4ICQ5	Acidithiobacillus_phage	5.9e-177	35.0
WP_015664818.1\|1935966_1937082_+	hypothetical protein	NA	NA	NA	NA
WP_015664819.1\|1937092_1937665_+	hypothetical protein	NA	NA	NA	NA
WP_015664820.1\|1937755_1939165_+\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A193GYC3	Enterobacter_phage	3.5e-118	49.0
WP_015664821.1\|1939176_1939680_+\|tail	phage major tail tube protein	A0A1B2LRS4	Wolbachia_phage	9.9e-39	44.6
WP_042340644.1\|1939790_1940051_+\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_015664823.1\|1940068_1940209_+	hypothetical protein	NA	NA	NA	NA
WP_015664824.1\|1940210_1942808_+\|tail	phage tail tape measure protein	D6PEW0	uncultured_phage	8.0e-07	68.3
WP_042338985.1\|1942810_1943197_+\|tail	phage tail protein	D4HTW5	Vibrio_phage	5.2e-32	52.8
WP_015664826.1\|1943196_1943406_+\|tail	tail protein X	NA	NA	NA	NA
WP_144058491.1\|1943474_1944500_+	hypothetical protein	A0A1B2LRT8	Wolbachia_phage	2.0e-30	30.8
WP_042338987.1\|1945040_1945955_+	N-acetylmuramoyl-L-alanine amidase	A0A1B0T6G1	Thiobacimonas_phage	1.3e-33	41.2

DBSCAN-SWA_2

2839231 : 2845477

Yellowstone_lake_phycodnavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015665644.1\|2839231_2840269_-	zinc-binding dehydrogenase	E3SJ82	Synechococcus_phage	1.3e-56	37.5
WP_015665645.1\|2840277_2841201_-	transketolase	A0A0P0YNE1	Yellowstone_lake_phycodnavirus	2.0e-16	31.0
WP_015665646.1\|2841197_2842046_-	transketolase	A0A0P0YMZ3	Yellowstone_lake_phycodnavirus	6.0e-12	36.1
WP_015665647.1\|2842091_2843090_-	GDP-mannose 4,6-dehydratase	A0A0N7KVW3	Yellowstone_lake_phycodnavirus	1.8e-36	36.2
WP_172889750.1\|2843102_2843735_-	SIS domain-containing protein	NA	NA	NA	NA
WP_015665648.1\|2843707_2844646_-	SDR family oxidoreductase	E3T4Y8	Cafeteria_roenbergensis_virus	7.6e-08	24.2
WP_015665649.1\|2844754_2845477_-	nucleotidyltransferase family protein	A0A127AW70	Bacillus_phage	1.1e-09	23.8

DBSCAN-SWA_3

4097800 : 4108408

uncultured_Mediterranean_phage(88.89%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015666696.1\|4097800_4098829_+	beta-N-acetylhexosaminidase	A0A1B1IVS3	uncultured_Mediterranean_phage	1.0e-21	42.0
WP_015666697.1\|4098825_4099665_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	8.2e-30	35.3
WP_015666698.1\|4099684_4100761_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	2.2e-43	47.5
WP_006614346.1\|4101040_4101274_+	twin-arginine translocase TatA/TatE family subunit	A0A1B1IVR9	uncultured_Mediterranean_phage	4.2e-08	55.4
WP_015666699.1\|4101383_4101911_+	twin-arginine translocase subunit TatB	NA	NA	NA	NA
WP_015666700.1\|4101907_4102732_+	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	1.0e-53	51.2
WP_015666701.1\|4102861_4104193_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	3.1e-100	53.1
WP_015666702.1\|4104296_4104653_+	hypothetical protein	NA	NA	NA	NA
WP_015666703.1\|4104751_4105519_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	8.3e-37	37.9
WP_042339753.1\|4105532_4105916_-	response regulator	NA	NA	NA	NA
WP_173424428.1\|4106192_4106840_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	4.5e-28	48.8
WP_015666706.1\|4106947_4108408_+	LysM peptidoglycan-binding domain-containing M23 family metallopeptidase	Q8SBN9	Clostridium_phage	7.3e-18	40.9

DBSCAN-SWA_4

4355515 : 4422670

Klosneuvirus(16.67%)

tail,protease,integrase,tRNA,holin

attL 4370147:4370163|attR 4387123:4387139

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_042339869.1\|4355515_4356250_+\|holin	phosphatidylcholine synthase	NA	NA	NA	NA
WP_015666930.1\|4356246_4356972_+	TerC family protein	A0A0R6PEZ3	Moraxella_phage	4.9e-39	40.9
WP_015666931.1\|4357138_4358113_+	quinone oxidoreductase	NA	NA	NA	NA
WP_015666932.1\|4358127_4358880_-	hypothetical protein	NA	NA	NA	NA
WP_015666933.1\|4359001_4359277_-	hypothetical protein	NA	NA	NA	NA
WP_015666934.1\|4359578_4360775_-	acetylornithine transaminase	A0A1V0SKB7	Klosneuvirus	1.0e-25	26.7
WP_015666935.1\|4361182_4362310_+	DUF2336 domain-containing protein	NA	NA	NA	NA
WP_015666936.1\|4362322_4363648_-	30S ribosomal protein S12 methylthiotransferase RimO	NA	NA	NA	NA
WP_015666937.1\|4363761_4364352_+	ANTAR domain-containing protein	NA	NA	NA	NA
WP_015666938.1\|4364348_4365503_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_015666939.1\|4365846_4367637_+	NirA family protein	NA	NA	NA	NA
WP_015666940.1\|4367633_4369247_+	sulfite reductase subunit alpha	NA	NA	NA	NA
WP_015666941.1\|4369407_4369560_+	hypothetical protein	NA	NA	NA	NA
WP_015666942.1\|4369525_4370335_-	LamB/YcsF family protein	NA	NA	NA	NA
4370147:4370163	attL	NA	NA	NA	NA
WP_015666943.1\|4370384_4371419_-	biotin-dependent carboxyltransferase	NA	NA	NA	NA
WP_015666944.1\|4371415_4372147_-	5-oxoprolinase subunit PxpB	NA	NA	NA	NA
WP_015666945.1\|4372393_4373092_+	ribonuclease activity regulator RraA	NA	NA	NA	NA
WP_015666946.1\|4373143_4373551_+	cupin domain-containing protein	NA	NA	NA	NA
WP_015666947.1\|4373619_4374531_-	DUF2147 domain-containing protein	NA	NA	NA	NA
WP_015666948.1\|4374622_4375099_-	Lrp/AsnC ligand binding domain-containing protein	NA	NA	NA	NA
WP_015666949.1\|4375247_4376267_+	1-aminocyclopropane-1-carboxylate deaminase	NA	NA	NA	NA
WP_015666951.1\|4377300_4377948_-	VOC family protein	NA	NA	NA	NA
WP_144058349.1\|4378166_4378433_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_015666953.1\|4378927_4379719_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_015666954.1\|4379817_4380318_+	DUF1993 domain-containing protein	NA	NA	NA	NA
WP_015666955.1\|4380356_4380737_-	hypothetical protein	NA	NA	NA	NA
WP_015666956.1\|4380915_4381914_-	hydroxyacid dehydrogenase	M1HUT5	Acanthocystis_turfacea_Chlorella_virus	3.8e-26	29.9
WP_015666957.1\|4381943_4383044_-	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	3.8e-19	29.9
WP_015666958.1\|4383060_4383972_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_015666959.1\|4383971_4384910_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_042339876.1\|4385034_4386375_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_042339878.1\|4386784_4387513_+	Spy/CpxP family protein refolding chaperone	NA	NA	NA	NA
4387123:4387139	attR	NA	NA	NA	NA
WP_083938627.1\|4390524_4391454_+	septal ring lytic transglycosylase RlpA family protein	F5B3X9	Synechococcus_phage	1.6e-18	58.3
WP_144058517.1\|4391563_4397260_-	IPT/TIG domain-containing protein	NA	NA	NA	NA
WP_015666965.1\|4397878_4398421_+\|tail	phage tail protein	E3T4R8	Cafeteria_roenbergensis_virus	2.1e-18	36.0
WP_015666966.1\|4398538_4399066_+\|tail	phage tail protein	A0A0U4JXW2	Arthrobacter_phage	7.0e-19	37.3
WP_015666967.1\|4399113_4399665_+\|tail	tail fiber protein	NA	NA	NA	NA
WP_144058518.1\|4399722_4400199_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_042340806.1\|4400220_4401177_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_015666970.1\|4401343_4402603_+	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	1.5e-48	34.6
WP_015666971.1\|4402607_4403288_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.0e-30	39.2
WP_015666972.1\|4403284_4404325_+	DNA polymerase III subunit delta'	NA	NA	NA	NA
WP_015666973.1\|4404407_4406558_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	4.6e-101	38.9
WP_015666974.1\|4406557_4407349_+	TatD family hydrolase	NA	NA	NA	NA
WP_015666975.1\|4407345_4408146_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_015666976.1\|4408318_4408948_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_015666977.1\|4409050_4410694_-	acyl-CoA synthetase	A0A2H4PQM9	Staphylococcus_phage	5.0e-31	31.0
WP_015666978.1\|4410722_4412609_-	TRAP transporter large permease subunit	NA	NA	NA	NA
WP_015666979.1\|4412698_4413718_-	TRAP transporter substrate-binding protein	NA	NA	NA	NA
WP_042340808.1\|4414193_4415027_+	hypothetical protein	NA	NA	NA	NA
WP_144058350.1\|4415052_4415889_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_015666982.1\|4415930_4416983_-	hypothetical protein	NA	NA	NA	NA
WP_042339882.1\|4417066_4418536_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-10	26.0
WP_015666984.1\|4418532_4419462_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_015666985.1\|4419464_4420340_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_042339885.1\|4420414_4421647_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_015666987.1\|4421944_4422670_-\|protease	site-2 protease family protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_020453

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection