CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_020829	Pseudomonas sp. ATCC 13867, complete sequence	3 crisprs	WYL,DEDDh,DinG,cas3,csa3	0	0	3	0

1. NC_020829

CRISPR-Cas detection and classification

Crispr_ID: NC_020829_1

• CRISPR_ID: NC_020829_1
• CRISPR_location: 259676-259740
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020829_1

Consensus_repeat	Method
AAGCCCAAGCCGAAACCCAAGCC	CRISPRCasFinder

spacers of NC_020829_1

>1.1|259699|19|NC_020829|CRISPRCasFinder
GGTGGAAAAGGCCGTCCCC

CRISPR arrays and Neighbor proteins around NC_020829_1

CRISPR arrays

The CRISPR arrays of NC_020829_1

>merge|NC_020829|1|259676-259740|CRISPRCasFinder
AAGCCCAAGCCGAAACCCAAGCCGGTGGAAAAGGCCGTCCCCAAGGTCGCGCCCAAGCCCAAACC

>NC_020829|1|1|259676-259740|CRISPRCasFinder
AAGCCCAAGCCGAAACCCAAGCC	GGTGGAAAAGGCCGTCCCC
AAGGTCGCGCCCAAGCCCAAACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020829.1|WP_015474993.1|252584_253769_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|367049
NC_020829.1|WP_015475005.1|263069_264713_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|183265
NC_020829.1|WP_015475006.1|265178_265538_+|multidrug-efflux-SMR-transporter	unknown	unknown	gnl|CDD|182471
NC_020829.1|WP_015475000.1|258117_259080_+|cobalamin-biosynthesis-protein-CobW	unknown	unknown	gnl|CDD|367104
NC_020829.1|WP_015475002.1|260294_260804_-|nucleoside-2-deoxyribosyltransferase	unknown	unknown	gnl|CDD|226140
NC_020829.1|WP_015475010.1|268346_269027_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|237220
NC_020829.1|WP_015475007.1|265531_265861_+|multidrug/spermidine-efflux-SMR-transporter-subunit-MdtI	unknown	unknown	gnl|CDD|182618
NC_020829.1|WP_015474996.1|255341_255743_-|hypothetical-protein	unknown	unknown	unknown
NC_020829.1|WP_015475003.1|260806_261889_-|calcium:proton-antiporter	unknown	unknown	gnl|CDD|223464
NC_020829.1|WP_015474998.1|256306_257509_+|GTP-binding-protein	unknown	unknown	gnl|CDD|223597
NC_020829.1|WP_015474995.1|254376_255264_-|GTP-cyclohydrolase-I-FolE2	unknown	unknown	gnl|CDD|237466
NC_020829.1|WP_015475004.1|262070_263021_+|adenosine-deaminase	unknown	unknown	gnl|CDD|236480
NC_020829.1|WP_086009586.1|250801_252220_-|MFS-transporter	unknown	unknown	gnl|CDD|341045
NC_020829.1|WP_015474997.1|255872_256277_+|RNA-polymerase-binding-protein-DksA	unknown	unknown	gnl|CDD|274124
NC_020829.1|WP_015474991.1|249474_250782_+|MFS-transporter	unknown	unknown	gnl|CDD|182433
NC_020829.1|WP_041712315.1|253909_254380_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_020829.1|WP_015475008.1|266253_267207_+|ATP-grasp-domain-containing-protein	unknown	unknown	gnl|CDD|237195
NC_020829.1|WP_015475011.1|269264_270002_+|metallophosphoesterase	unknown	unknown	gnl|CDD|277367
NC_020829.1|WP_015475009.1|267323_268259_-|AEC-family-transporter	unknown	unknown	gnl|CDD|223751
NC_020829.1|WP_015474999.1|257687_258041_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020829.1|WP_015474993.1|252584_253769_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|367049	pfam02353, CMAS, Mycolic acid cyclopropane synthetase. This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.	9.36211e-130
NC_020829.1|WP_015475005.1|263069_264713_-|STAS-domain-containing-protein	gnl|CDD|183265	PRK11660, PRK11660, putative transporter; Provisional.	4.56322e-180
NC_020829.1|WP_015475006.1|265178_265538_+|multidrug-efflux-SMR-transporter	gnl|CDD|182471	PRK10452, PRK10452, multidrug/spermidine efflux SMR transporter subunit MdtJ.	4.85261e-31
NC_020829.1|WP_015475000.1|258117_259080_+|cobalamin-biosynthesis-protein-CobW	gnl|CDD|367104	pfam02492, cobW, CobW/HypB/UreG, nucleotide-binding domain. This domain is found in HypB, a hydrogenase expression / formation protein, and UreG a urease accessory protein. Both these proteins contain a P-loop nucleotide binding motif. HypB has GTPase activity and is a guanine nucleotide binding protein. It is not known whether UreG binds GTP or some other nucleotide. Both enzymes are involved in nickel binding. HypB can store nickel and is required for nickel dependent hydrogenase expression. UreG is required for functional incorporation of the urease nickel metallocenter. GTP hydrolysis may required by these proteins for nickel incorporation into other nickel proteins. This family of domains also contains P47K, a Pseudomonas chlororaphis protein needed for nitrile hydratase expression, and the cobW gene product, which may be involved in cobalamin biosynthesis in Pseudomonas denitrificans.	4.06553e-47
NC_020829.1|WP_015475002.1|260294_260804_-|nucleoside-2-deoxyribosyltransferase	gnl|CDD|226140	COG3613, COG3613, Nucleoside 2-deoxyribosyltransferase [Nucleotide transport and metabolism].	1.18676e-51
NC_020829.1|WP_015475010.1|268346_269027_-|SDR-family-oxidoreductase	gnl|CDD|237220	PRK12828, PRK12828, short chain dehydrogenase; Provisional.	9.88103e-81
NC_020829.1|WP_015475007.1|265531_265861_+|multidrug/spermidine-efflux-SMR-transporter-subunit-MdtI	gnl|CDD|182618	PRK10650, PRK10650, multidrug/spermidine efflux SMR transporter subunit MdtI.	5.64901e-46
NC_020829.1|WP_015475003.1|260806_261889_-|calcium:proton-antiporter	gnl|CDD|223464	COG0387, ChaA, Ca2+/H+ antiporter [Inorganic ion transport and metabolism].	1.03549e-86
NC_020829.1|WP_015474998.1|256306_257509_+|GTP-binding-protein	gnl|CDD|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	1.37595e-117
NC_020829.1|WP_015474995.1|254376_255264_-|GTP-cyclohydrolase-I-FolE2	gnl|CDD|237466	PRK13674, PRK13674, GTP cyclohydrolase I FolE2.	4.18499e-118
NC_020829.1|WP_015475004.1|262070_263021_+|adenosine-deaminase	gnl|CDD|236480	PRK09358, PRK09358, adenosine deaminase; Provisional.	1.70895e-164
NC_020829.1|WP_086009586.1|250801_252220_-|MFS-transporter	gnl|CDD|341045	cd17502, MFS_Azr1_MDR_like, Saccharomyces cerevisiae Azole resistance protein 1 (Azr1p), and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including various Saccharomyces cerevisiae proteins such as azole resistance protein 1 (Azr1p), vacuolar basic amino acid transporter 1 (Vba1p), vacuolar basic amino acid transporter 5 (Vba5p), and Sge1p (also known as Nor1p, 10-N-nonyl acridine orange resistance protein, and crystal violet resistance protein). MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.7675e-69
NC_020829.1|WP_015474997.1|255872_256277_+|RNA-polymerase-binding-protein-DksA	gnl|CDD|274124	TIGR02420, RNA_polymerase-binding_transcription_factor_DksA, RNA polymerase-binding protein DksA. The model that is the basis for this family describes a small, pleiotropic protein, DksA (DnaK suppressor A), originally named as a multicopy suppressor of temperature sensitivity of dnaKJ mutants. DksA mutants are defective in quorum sensing, virulence, etc. DksA is now understood to bind RNA polymerase directly and modulate its response to small molecules to control the level of transcription of rRNA. Nearly all members of this family are in the Proteobacteria. Whether the closest homologs outside the Proteobacteria function equivalently is unknown. The low value set for the noise cutoff allows identification of possible DksA proteins from outside the proteobacteria. TIGR02419 describes a closely related family of short sequences usually found in prophage regions of proteobacterial genomes or in known phage. [Transcription, Transcription factors, Regulatory functions, Small molecule interactions].	1.51283e-38
NC_020829.1|WP_015474991.1|249474_250782_+|MFS-transporter	gnl|CDD|182433	PRK10406, PRK10406, alpha-ketoglutarate transporter; Provisional.	0
NC_020829.1|WP_041712315.1|253909_254380_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.47309e-13
NC_020829.1|WP_015475008.1|266253_267207_+|ATP-grasp-domain-containing-protein	gnl|CDD|237195	PRK12767, PRK12767, carbamoyl phosphate synthase-like protein; Provisional.	8.8228e-45
NC_020829.1|WP_015475011.1|269264_270002_+|metallophosphoesterase	gnl|CDD|277367	cd07424, MPP_PrpA_PrpB, PrpA and PrpB, metallophosphatase domain. PrpA and PrpB are bacterial type I serine/threonine and tyrosine phosphatases thought to modulate the expression of proteins that protect the cell upon accumulation of misfolded proteins in the periplasm. The PPP (phosphoprotein phosphatase) family, to which PrpA and PrpB belong, is one of two known protein phosphatase families specific for serine and threonine. This family also includes: PP1, PP2A, PP2B (calcineurin), PP4, PP5, PP6, PP7, Bsu1, RdgC, PrpE, and ApA4 hydrolase. The PPP catalytic domain is defined by three conserved motifs (-GDXHG-, -GDXVDRG- and -GNHE-). The PPP enzyme family is ancient with members found in all eukaryotes, and in most bacterial and archeal genomes. Dephosphorylation of phosphoserines and phosphothreonines on target proteins plays a central role in the regulation of many cellular processes. PPPs belong to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	9.91719e-67
NC_020829.1|WP_015475009.1|267323_268259_-|AEC-family-transporter	gnl|CDD|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	1.81636e-49

Protein sequences

>NC_020829.1|WP_015475000.1|258117_259080_+|cobalamin-biosynthesis-protein-CobW
MLKQIPTHLIAGPLGAGKTSLLHDLLAQRPAEERWAVLVNEFGQVGLDAALLCRDEEGIALGEVAGGCLCCVNGAPFQVGLGRLLRKARPQRLFIEPSGLGHPSQLLAQLRATPWQGVLAVQPLVMVLDAASLAAGQPLPEPQREALEQAGLMLLNKSETLDDAARAQLLVALPALPARWTTQGRLALSELPASPLEAPGAGLPILPASVEAGVLLRREQPLRQVRIEDGRQAVGWRFHPDWRFRIAELDAWLAALPGLLRAKAVLHGEAGWLACNRTERTAPWTPSPWRRDSRIELILAAQVDPQPLHDALLRCAIEPG
>NC_020829.1|WP_015474999.1|257687_258041_-|hypothetical-protein
MRQLLPLAFACLPLLAHGEACVVHSQGANLDVKVCQQNRSIPATLFRDGFCQPQLKDQTVQVTYADHCPSGAFGVCENAQVQGMPYRQDIHYYGVPSDARILQPFCETQSHGQWRKP
>NC_020829.1|WP_015474998.1|256306_257509_+|GTP-binding-protein
MNRLLPVTVLSGFLGAGKSTLLNHVLKNREDLKVAVIVNDMSEINIDGREVQRDVSLNRGQERLVEMSNGCICCTLREDLLEEVSRLAGEGRFDYLLIESTGISEPLPVAETFTFRDEQGRSLSDLARLDTLVTVVDGLNFLADYQGADSLAERGETLGEDDERSLSDLLVEQVEFADVILVSKIDLIGSAERDELLAILRRLNPDADIRPMVMGQVPLATILDTGRFDFQRAERAPGWLKELRGEHLPETEAYGIASSVYRARRPFHPQRFHDFLAQPWSNGRLLRSKGFFWLASRYREAGSWSQAGGLMRHGLAGRWWRFVPREAWPQDTAELQVVLRHWDENSGDCRQELVFIGQNLDFARLFAELDRCLLDDAEMAAGTTAWKRLPDPFEPWEAPT
>NC_020829.1|WP_015474997.1|255872_256277_+|RNA-polymerase-binding-protein-DksA
MTEQELLAQPGDAYMSEAQQGYFRELLLHQRGELQARIDEEFRALQDGERASDDADIASREEERQWQLRRLEREKKLLDKIDQALERLVRGDYGWCEETAEPIGLRRLLLRPTASLCIEAKERQERRELHVREA
>NC_020829.1|WP_015474996.1|255341_255743_-|hypothetical-protein
MLRRALLFCLLAPFAHASGSAPLPFPGEQPARCAWSASVLACMDDSGNRYSIATQGHDTYLRGFEASSGRRWAQTGTRYGSLTFFSGVTSDGQVWVGTSRGIGWTNISRFSSSTGDSARLTCGRVSGCKQQER
>NC_020829.1|WP_015474995.1|254376_255264_-|GTP-cyclohydrolase-I-FolE2
MTALLPDIACQSTHLPVPLDWVGMQGIAVPLRIAGERVAAYADAGVSLDEADARGIHMSRLYLELEALADTELSPALLRDLLRQFLRSHAQLSRRASLVLRFELMLRRPALVSPLSGWKRYPCEIHAQLEDDVLQLELRLSLPYSSTCPCSAALARQLIQERFDADFAGRPLKASEVRAWLGSPQGILATPHSQRSEARLQLRLDPAARTFAFSELIDHAEAALGTAVQTAVKRADEQAFALANGQNLMFCEDAARRLHRALLQREEVSGFEVRVVHAESLHAHDAVAASRWVRP
>NC_020829.1|WP_041712315.1|253909_254380_+|GNAT-family-N-acetyltransferase
MVSFFPELSLVELTPAQAPWPLLLLADPSRAQIERYLPQSRVLALSDSEAVRGVLTLTARSWGVIEITNLAVEEEWQGRGLARRLLTAAIDAARAIGALRLDIATGNSSLAQLGLYQRMGFRIACVEHDYFSLNYPEPIIENGIRCRDRIRLDLVL
>NC_020829.1|WP_015474993.1|252584_253769_+|class-I-SAM-dependent-methyltransferase
MKANLPSELLSLQLPLRIRIGETQAFDLGPDPQVTLVVRDPTLLTEITQPSLDVLGRAYVEKRMDIEGPIGDVIAMGDALSAALGTDDAGGDYVRESHDKSTDAEAIHYHYDLSNAFYQLWLDPEMVYSCAYYETGSEDLATAQVAKLRHLCRKLRLKPGEKLLDVGCGWGGLARLAAKEFGVQVHGITLSEEQLKLGRERIRAEGLEGKVTLELRDYRDLPRDGRYDKVVSVGMFEHVGHANLGIYFQHLFDAVRPGGLVMNHGITSSNTDGRPVGRGAGDFIDRYVFPHGELPHLSLAVARMSEAGLEVVDVEGLRLHYARTLDFWSANLEAKLAEAARLVPDQALRIWRLYLAGCAYGFKKGWINLHQILASRPHADGSQEVPWSRRDIYV
>NC_020829.1|WP_086009586.1|250801_252220_-|MFS-transporter
MLAIFLGALDQTIVAVSLPAISAGFGDFDLLAWVISGYMVAMTISMPIYGKLGDLYGRRVLMLFAIGVFTAASALCGAAQSMEQLVLARVLQGIGAGGMMSVSQAIIGDIVPPRERGRYQGYFSSMYAVASIAGPVLGGLLTEYLSWRWVFLINLPVGLVALAVSRRTLRGLPVPGRQPVIDYLGTALMIAGLGSLLLAITEVGQGARWNDPQMLGLFAAALVLIALFVMQERRAPEPLVPMQLFRIRAATLSWLISFFASFQVISLSVLVPLRFQSVTGAGADSAALHLLPLAMGVPLGAYCCGRLTAVLGRYKPQIVAGALLAPGAIAGLALTSPDAYLLSGLCMLLTGIAAGTQFPTSLVAAQSAVDSRYLGVATSNITLFRSLGGAVGIALMSALLLAMLQPLAGDAGHGLSASALLDSLGGAGHEAQRQVLDQVFSHLFLISAGFGVLTLLIALALPDHALRGRADN
>NC_020829.1|WP_015474991.1|249474_250782_+|MFS-transporter
MNAPASVPQYSAHERRSRILAIVGASSGNLVEWFDFYVYAFTALYFAHAFFPSDNPTVQLLNTAGVFAAGFLMRPIGGWMFGRIADKKGRKTAMMISVLMMCGGSLAIAVMPTYATIGVAAPALLLLARLFQGLSVGGEYGTSATYMSEVALKGQRGFFASFQYVTLIGGQLLAVLVVVVLQQLLSTDELREWGWRIPFVVGAITAVIAFYLRRSLSETAKASNLNRKESGTLTELFAHHKRAFFTVLGFTAGGSLIFYTFTTYMQKYLVNTAGMDPKVASGVMTFALFCYMCMQPLFGALSDRIGRKTSMLWFGILGMLFTWPILSALKAVSSPYLAFVLIIAAMAIVSLYTSISGLIKSEMFPPQIRALGVGLSYAVGNAIFGGSAEYVALGLKSLGIEEYFYIYVSVMCGVALVVCLLLPDLRKVSYLNDED
>NC_020829.1|WP_015475002.1|260294_260804_-|nucleoside-2-deoxyribosyltransferase
MLKIYLAGPDVFRPDAFEQGERLKALCAEFGLLGLYPLDHSVPEGIDRPREQALWIYQANLALIAEADALVANLNPFRGAEPDSGTAFELGYAAALGKPLYGYIDAGGSCTERLPREWQGAEPGRDRDGNQVEAFDLPLNLMLGVPAQIAVGGLREALELLKAELFPEE
>NC_020829.1|WP_015475003.1|260806_261889_-|calcium:proton-antiporter
MLRALKDEKLLILALLVALAVYPLEHGLLSGGKLLAGITASVLLAVIIGVSLRVAHHAEILAEKVGEPYGTMILTLAAVLVEVVILAIMMGHNHSPTLARDTIYAAVMLDMNGILGLAALLGGLKHGEQSYNDDSGKTYVTMILTAVGISMVVPELIPAEQWKLYSMFTIGCMVMLYALFLRMQTGQHSYFFSYNYAAHGEQHTAHAAPGDSRRSILLLVAGVVLIGALAEVMSKALDVGLQGSGVPPIVPALLVAAISASPEILTALRAALANRMQPVVNIALGASLSTVILTVPVIEALALFKGQPIQMAMTPLQTGMMFITLMVAGFNLHDGKTNAIEGMTHFVLFATFLMLSLMGL
>NC_020829.1|WP_015475004.1|262070_263021_+|adenosine-deaminase
MYDWLNALPKAELHLHLEGSLEPELLFALAERNRIALPWGDVESLRQAYAFNNLQEFLDLYYAGADVLRTEQDFYDLTWAYLAKCKAQNVIHVEPFFDPQTHTDRGIPFEVVLRGIQGALKDGEQQLGISHGLILSFLRHLSEDEAFKTLEQALPFRDAFIAVGLDSSEVGHPPSKFQRVFDRARSEGFLTVAHAGEEGPPEYIWEALDLLKIERIDHGVRAIEDERLMRRIIDEQIPLTVCPLSNTKLCVFDHMREHNILDMLERGVKVTVNSDDPAYFGGYVTENFHALHEHLGMTKEQAQRLAQNSLDARLVR
>NC_020829.1|WP_015475005.1|263069_264713_-|STAS-domain-containing-protein
MIALRDAWKAGLFGHEHWTRNLVAGVIVGVVALPLAMAFAIASGVKPEQGIYTAIFAGALVSLLGGSRVQIAGPTGAFIVILAGITAKYGIDGLQIATLMAGAILVLLGVSRLGTIIRFIPAPVIVGFTAGIGVIIWVGQWKDFFGLPAVNGEHFHQKVWHLLQALPQLHVATTLLALLSLALVLFAPRIAALRRVPGPLVAMVVVTAIQSLFHFDGVATIGSAFGGIPQGLPSFSLPEVTLPRVLELIGPAFAIAMLGAIESLLSAVVADGMAGTRHDSNQELIGQGIANLVTPLFGGIAATGAIARTATNIRNGGNSPLAGVTHAATLVLILLFLAPLASNIPLCALAAILFVVAWNMSEARHFLFMVKRAPRADVAILLITFGLTVFSDLVIAVNIGVILAMLHFLRRMASSVEVHADEGTELEVELRGRGLAELPPGVLVYSIEGPLFFGAAETFERALAQTHTDPKVLIIRLRRVPFMDITGLQTLQEVIEDLQRRGIEVRLCEANARVLGKLRKTGILDVPRAAIYHPDFPAALTASTAAP
>NC_020829.1|WP_015475006.1|265178_265538_+|multidrug-efflux-SMR-transporter
MRSWIYLFAAIGFEVVGTTSMKLTHALYPVAGLLLMYVMVGLSYYFLALAIKHVPVGVAYALWEGIGIVLITLVSAAWLGENLTLEKGLGLAVMIAGILLVKSGTRKGEPEAGREAATC
>NC_020829.1|WP_015475007.1|265531_265861_+|multidrug/spermidine-efflux-SMR-transporter-subunit-MdtI
MLNHELIPMAWLGLAIVLEVIANLLLKYSDGFRKRALGVFSILCVLGAFTALSQAVRGIELSVAYAVWGGFGILATVAMGWALFGQRLAWRGWVGLTMLVLGMGLLKLA
>NC_020829.1|WP_015475008.1|266253_267207_+|ATP-grasp-domain-containing-protein
MTAIGSFSAEAVITSLRRDPQARVVGVSSLPREWNASSPLLDAFHRVPAARDVLSYVGRVLDICETERVTHVLPLIDPEVDAFTRHQEAFSSRGITLCMAPAETVYISRDKWLVFEAFRDNPDIRPIPTWKMEDSAVEDLAFPLLAKPRDGRNSEGLVRIYDGEDLRHFRKKLKDREYVVQPLLDGDVCVVDIVRQRETGQWAGIARQELVRTPNGAGLTVRMLNDPLLVDAAGQIARTLDANGCINIEFLVQDGTSQLMDINPRFSGGIVFSHLSGYDMVSNHLRCFSGSMLDEPVAPIPAIHARHYVEVTFTDPQ
>NC_020829.1|WP_015475009.1|267323_268259_-|AEC-family-transporter
MFHVLSVVLPIFALILVGWLCRRTNRLGPQAASEINKLVVWLCLPALLFKVTATSTWAEIWQPGFLAAFTGGCLLVFFATLAWRLLQGRALPAASIDGLSASYANTGYMGIPLCLLVFGQDGLEPALIASLLVVCVLFAIAVVCIEVGLQNEKHIGRAIAVVLKALGKNPLVVSPILGGLWAASGIGLPMPLLHFLDMLAAATTPCALVSLGLFLAQKQETQGPRVGAWPLVAIKLVGQPLLTGFLAYTVFDLPPLWADSALLLSALPTGTGPFMLAEYYRREAAVVSRSILVSTLGSLVTLSLCLLWIAR
>NC_020829.1|WP_015475010.1|268346_269027_-|SDR-family-oxidoreductase
MNKIVAITGGFGYLGSVVGQAFAAAGWQVALLDRAVSPRYPQAGALSLGSVDLTDSAAARTAIDQAAEHFGGLDALINVAGGFHWETLADGDVDTWDLMYRINLRTAVVSSQAALAHLKARGHGRILNIAATAATRAALGMGAYAAAKAGVMRLTEALAEELKDARITVNALMPSIIDTPQNRTDMPDAEFDRWVRPEQLAATLLFLASDNAAAITGACIPVTGRV
>NC_020829.1|WP_015475011.1|269264_270002_+|metallophosphoesterase
MNTLLPERPLQRFARNLRGRDFVVGDVHGHFELLERLLERVAFDTAADRLFAAGDLVDRGPYSPRVLEWLGHPWFASVRGNHEQLVIDSVLAGDDRDLHFRNGGAWLYALPQDEREHIARRLQHLPLAIEVDIGESRRVGIVHAEAPISSAFPDWDSGMAALAGELGNAARRNAAALAMWARTRIEGEDDTRVPGLERLYVGHTAQARVRRLGNTHYIDTGSGYADGTLSLVDLHSGAVETAVAH

Crispr_ID: NC_020829_2

• CRISPR_ID: NC_020829_2
• CRISPR_location: 3496984-3497078
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020829_2

Consensus_repeat	Method
CGAATGATCCATGCCGGCCATGC	CRISPRCasFinder

spacers of NC_020829_2

>2.1|3497007|49|NC_020829|CRISPRCasFinder
GCGAATGATCCATGCCGGCCATGCCTGAAGCCTCCTGGCCCTGCATCGC

CRISPR arrays and Neighbor proteins around NC_020829_2

CRISPR arrays

The CRISPR arrays of NC_020829_2

>merge|NC_020829|2|3496984-3497078|CRISPRCasFinder
CGCGTGATCCATGCCGGCCATCTGCGAATGATCCATGCCGGCCATGCCTGAAGCCTCCTGGCCCTGCATCGCCGAATGGTCCATGCCGGCCATGC

>NC_020829|2|2|3496984-3497078|CRISPRCasFinder
CGCGTGATCCATGCCGGCCATCT	GCGAATGATCCATGCCGGCCATGCCTGAAGCCTCCTGGCCCTGCATCGC
CGAATGGTCCATGCCGGCCATGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020829.1|WP_015477818.1|3493688_3494270_+|HD-domain-containing-protein	unknown	unknown	gnl|CDD|132319
NC_020829.1|WP_041712635.1|3499853_3501167_+|heavy-metal-sensor-histidine-kinase	unknown	unknown	gnl|CDD|273593
NC_020829.1|WP_015477813.1|3489387_3489870_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NC_020829.1|WP_015477824.1|3499173_3499854_+|heavy-metal-response-regulator-transcription-factor	unknown	unknown	gnl|CDD|130454
NC_020829.1|WP_015477827.1|3502117_3503050_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_020829.1|WP_015477816.1|3492120_3492837_-|UTRA-domain-containing-protein	unknown	unknown	gnl|CDD|132380
NC_020829.1|WP_015477817.1|3492948_3493692_+|phosphatase	unknown	unknown	gnl|CDD|184075
NC_020829.1|WP_015477820.1|3494676_3495507_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl|CDD|236986
NC_020829.1|WP_015477821.1|3495750_3496458_-|copper-resistance-protein-B	unknown	unknown	gnl|CDD|377498
NC_020829.1|WP_015477815.1|3491235_3491940_-|VacJ-family-lipoprotein	unknown	unknown	gnl|CDD|377309
NC_020829.1|WP_015477829.1|3503890_3504562_-|transglutaminase-family-protein	unknown	unknown	gnl|CDD|224224
NC_020829.1|WP_015477814.1|3489866_3491051_-|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|381107
NC_020829.1|WP_015477826.1|3501341_3502121_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|237896
NC_020829.1|WP_015477830.1|3504783_3507219_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|236528
NC_020829.1|WP_015477832.1|3507839_3508250_+|hypothetical-protein	unknown	unknown	unknown
NC_020829.1|WP_015477828.1|3503156_3503774_-|glutathione-S-transferase	unknown	unknown	gnl|CDD|198289
NC_020829.1|WP_015477823.1|3498201_3498753_-|cupredoxin-family-protein	unknown	unknown	gnl|CDD|259873
NC_020829.1|WP_015477819.1|3494346_3494610_+|DUF4404-family-protein	unknown	unknown	gnl|CDD|379579
NC_020829.1|WP_015477812.1|3488402_3489323_+|transaldolase	unknown	unknown	gnl|CDD|235381
NC_020829.1|WP_015477831.1|3507347_3507767_+|hypothetical-protein	unknown	unknown	gnl|CDD|234714

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020829.1|WP_015477818.1|3493688_3494270_+|HD-domain-containing-protein	gnl|CDD|132319	TIGR03276, Phn-HD, phosphonate degradation operons associated HDIG domain protein. This small clade of proteins are found adjacent to other genes implicated in the catabolism of phosphonates. They are members of the TIGR00277 domain family and contain a series of five invariant histidines (the domain in general has only four).	6.8321e-77
NC_020829.1|WP_041712635.1|3499853_3501167_+|heavy-metal-sensor-histidine-kinase	gnl|CDD|273593	TIGR01386, Probable_sensor_protein_PcoS, heavy metal sensor kinase. Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.	1.01456e-163
NC_020829.1|WP_015477813.1|3489387_3489870_-|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	7.79072e-14
NC_020829.1|WP_015477824.1|3499173_3499854_+|heavy-metal-response-regulator-transcription-factor	gnl|CDD|130454	TIGR01387, Transcriptional_regulatory_protein_PcoR, heavy metal response regulator. Members of this family contain a response regulator receiver domain (pfam00072) and an associated transcriptional regulatory region (pfam00486). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc. Most members encoded by genes adjacent to genes for encoding a member of the heavy metal sensor histidine kinase family (TIGRFAMs:TIGR01386), its partner in the two-component response regulator system. [Regulatory functions, DNA interactions].	3.22969e-110
NC_020829.1|WP_015477827.1|3502117_3503050_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.463e-102
NC_020829.1|WP_015477816.1|3492120_3492837_-|UTRA-domain-containing-protein	gnl|CDD|132380	TIGR03337, phnR, phosphonate utilization transcriptional regulator PhnR. This family of proteins are members of the GntR family (pfam00392) containing an N-terminal helix-turn-helix (HTH) motif. This clade is found adjacent to or inside of operons for the degradation of 2-aminoethylphosphonate (AEP) in Salmonella, Vibrio Aeromonas hydrophila, Hahella chejuensis and Psychromonas ingrahamii. [Regulatory functions, DNA interactions].	5.56478e-77
NC_020829.1|WP_015477817.1|3492948_3493692_+|phosphatase	gnl|CDD|184075	PRK13478, PRK13478, phosphonoacetaldehyde hydrolase; Provisional.	5.9161e-25
NC_020829.1|WP_015477820.1|3494676_3495507_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl|CDD|236986	PRK11792, queF, 7-cyano-7-deazaguanine reductase; Provisional.	0
NC_020829.1|WP_015477821.1|3495750_3496458_-|copper-resistance-protein-B	gnl|CDD|377498	pfam05275, CopB, Copper resistance protein B precursor (CopB). This family consists of several bacterial copper resistance proteins. Copper is essential and serves as cofactor for more than 30 enzymes yet a surplus of copper is toxic and leads to radical formation and oxidation of biomolecules. Therefore, copper homeostasis is a key requisite for every organism. CopB serves to extrude copper when it approaches toxic levels.	1.86675e-105
NC_020829.1|WP_015477815.1|3491235_3491940_-|VacJ-family-lipoprotein	gnl|CDD|377309	pfam04333, MlaA, MlaA lipoprotein. MlaA is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane. MlaA is required for the intercellular spreading of Shigella flexneri. It is attached to the outer membrane by a lipid anchor.	9.91955e-109
NC_020829.1|WP_015477829.1|3503890_3504562_-|transglutaminase-family-protein	gnl|CDD|224224	COG1305, COG1305, Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism].	4.44424e-20
NC_020829.1|WP_015477814.1|3489866_3491051_-|SpoIIE-family-protein-phosphatase	gnl|CDD|381107	cd17555, REC_RssB-like, phosphoacceptor receiver (REC) domain of Pseudomonas aeruginosa RssB and similar domains. Pseudomonas aeruginosa RssB is an orphan atypical response regulator containing a REC domain and a PP2C-type protein phosphatase output domain. Its function is still unknown. Escherichia RssB, which is not included in this subfamily, is a ClpX adaptor protein which alters ClpX specificity by mediating a specific interaction between ClpX and the substrates such as RpoS, an RNA polymerase sigma factor. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	3.5679e-68
NC_020829.1|WP_015477826.1|3501341_3502121_-|ABC-transporter-permease	gnl|CDD|237896	PRK15066, PRK15066, inner membrane transport permease; Provisional.	1.98857e-161
NC_020829.1|WP_015477830.1|3504783_3507219_+|acyl-CoA-dehydrogenase	gnl|CDD|236528	PRK09463, fadE, acyl-CoA dehydrogenase; Reviewed.	0
NC_020829.1|WP_015477828.1|3503156_3503774_-|glutathione-S-transferase	gnl|CDD|198289	cd03180, GST_C_2, C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases. Glutathione S-transferase (GST) C-terminal domain family, unknown subfamily 2; composed of uncharacterized bacterial proteins, with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress. GSTs also show GSH peroxidase activity and are involved in the synthesis of prostaglandins and leukotrienes. The GST fold contains an N-terminal thioredoxin-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. GSH binds to the N-terminal domain while the hydrophobic substrate occupies a pocket in the C-terminal domain.	7.29497e-55
NC_020829.1|WP_015477823.1|3498201_3498753_-|cupredoxin-family-protein	gnl|CDD|259873	cd04211, Cupredoxin_like_2, Uncharacterized Cupredoxin-like subfamily. Cupredoxins contain type I copper centers and are involved in inter-molecular electron transfer reactions. Cupredoxins are blue copper proteins because they have an intense blue color due to the presence of a mononuclear type 1 (T1) copper site. Structurally, the cupredoxin-like fold consists of a beta-sandwich with 7 strands in 2 beta-sheets, which is arranged in a Greek-key beta-barrel. Some of these proteins have lost the ability to bind copper. Majority of family members contain multiple cupredoxin domain repeats; ceruloplasmin and coagulation factors V/VIII have six repeats; Laccase, ascorbate oxidase, and spore coat protein A, and multicopper oxidase CueO contain three repeats; and nitrite reductase has two repeats. Others are mono-domain cupredoxins, such as plastocyanin, pseudoazurin, plantacyanin, azurin, rusticyanin, stellacyanin, quinol oxidase and the periplasmic domain of cytochrome c oxidase subunit II.	3.05163e-45
NC_020829.1|WP_015477819.1|3494346_3494610_+|DUF4404-family-protein	gnl|CDD|379579	pfam14357, DUF4404, Domain of unknown function (DUF4404). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 90 amino acids in length. There are two completely conserved residues (P and G) that may be functionally important.	1.12272e-24
NC_020829.1|WP_015477812.1|3488402_3489323_+|transaldolase	gnl|CDD|235381	PRK05269, PRK05269, transaldolase B; Provisional.	0
NC_020829.1|WP_015477831.1|3507347_3507767_+|hypothetical-protein	gnl|CDD|234714	PRK00286, xseA, exodeoxyribonuclease VII large subunit; Reviewed.	1.96059e-05

Protein sequences

>NC_020829.1|WP_015477821.1|3495750_3496458_-|copper-resistance-protein-B
MKRIATVACAATLGLALPAQSAEMDDMPMGSLLIQRLESRFHGNDQALGWEAQGWYGTDYQKLRLKLEGERDAGGPTTDNEVQLLYQRMVADFWDWQVGVRYDDQPGPSRTYAVLGIQGLAPQWFEVDANLFLSENGDPSLRLETEYELLLTQQLILEPSLEYNLALADDRDIGVGAGGSELEAGLRLRYEVRREFAPYFGYVWNKTYGRSGDIARAEGEVDEEGYWVAGVRMWF
>NC_020829.1|WP_015477820.1|3494676_3495507_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MHHPAEHSPLGKSSEYVSTYAPELLFPISRTTKWAELGLTAETLPYRGVDIWNCYELSWLTASGKPVVAIGEFAIPAQSPNIIESKSFKLYLNSLNQTAFDSADAVRTLMERDLSAAAGAPVRVRVRSLDDVAGEGMALIEGTCIDGLDLAVDSYDRPRPELLRCDDTRRVDEVLYSHLLKSNCPVTGQPDWGTLVVEYTGPALDAASLLAYVVSFRQHQDFHEQCVERIYLDLQRLLQPARLTVYARYVRRGGLDINPYRSSEAVQPDNRRLVRQ
>NC_020829.1|WP_015477819.1|3494346_3494610_+|DUF4404-family-protein
MPTQRLQQELQALREQLERQPPLTEDDRAALRALIKDIEMQLANEEALADETLTDSINLAVERFEASHPTLAGTLRSIMQSLANMGI
>NC_020829.1|WP_015477818.1|3493688_3494270_+|HD-domain-containing-protein
MKPARHRFIDELAERFASHGAEPYGEAISQAEHALQCATLAERAGCADSLVIAALLHDIGHLYEDPAVLETRDLRHEEFGANLLRELLPESVWQPVRLHVAAKRYLCAVDPAYQAGLSWASRQSLALQGGAFDERAASAFVSAPYAQDAITLRRLDDLGKDPSMRTPELEHFFPLLERLLHVDRHQAGVRAAS
>NC_020829.1|WP_015477817.1|3492948_3493692_+|phosphatase
MPATADLPRFTTLLFGLSGDLVDFGARTLPVALRRTCPDCPPERLADALVLPPQDALEHALGRSADTQERSRFQSALDEAAQAHAEATPGALDALQALHEHGVPCAWLDELPAPTTLRLATALDERLAAGLEVGGRQWPAPDACWQALMRLDSPRLDGCVLVSSQPRLLQAGLNAGLWTIGLAASGPLCGHAPGDWDALANLERDRLRAQATLGLYRLGVHSVIDHLGELDSCLQDITSRRLKGEKP
>NC_020829.1|WP_015477816.1|3492120_3492837_-|UTRA-domain-containing-protein
MPVEPMPHYLRIRDQLARDIAESTLGPRLPPERELAERFGCTRVTLREALQQLETEGVLYRENRRGWFVSPPRIRYNPTRTTGFMDYVQAQGRTPRTEVLSAERCAAGPLLARRMGLADDAEVFRVRRRRWVDERPVMLEEIVLDAGWCPGLLDEALDRSLTRVLRERLGLTLSRCELMMHPTALDDVWAAPLQLTPGSPGLHVERTNYTAGGRLVEFDREFWRSDALEIVIDARFPD
>NC_020829.1|WP_015477815.1|3491235_3491940_-|VacJ-family-lipoprotein
MRPLGVQWTKRCLSLLAATCLATTPILAQAESEDDPWESINRPIFTFNDTLDTYALKPLAQGYQYVTPNFVQDGVHNFFSNIGDVRNLVNDLLQLKMRDAGVDTSRLLFNTTFGLAGFFDVATHMGLRRNDEDFGQTLGHYGVGSGPYVMLPLLGPSTLRDAPSLIPDAYTGPYPYIDNVSVRNSIRGVDIVDTRADLLKSEKLISGDKYTFIRNAYLQNREFKVKDGQVEDDF
>NC_020829.1|WP_015477814.1|3489866_3491051_-|SpoIIE-family-protein-phosphatase
MHKPSASLLIIDDDDVVRESLAAYLEDSGFTVQQATNGQQGLQVFEHSLPDLVICDLRMPQMDGLELIRRVSEMAVETPVIVLSGAGVMSDAVEALRLGAADYLIKPLEDLAVLEHSVRRALDRAFLRSENRRYREKLETANRELQASLNLLQEDQNAGRQVQMNMLPETPWESDGLVFSHQIIPSLYLSGDFVDYFRVDARRIGFYLADVSGHGASSAFVTVLLKFMTTRLLYESRRNGMLPEFKPSDVLGHINRGLINCKLGKHVTMLGGVIDLDTDRLTYSIGGHLPLPVLYVDGEARYLEGRGLPVGLFDEATYEDHVLDLPKSFSLSLFSDGILDVLPGVTLKEKETALPQQVVAAGGTLDGLRQVFGLAKLSEMPDDIALLVLSRNLA
>NC_020829.1|WP_015477813.1|3489387_3489870_-|STAS-domain-containing-protein
MSTGKIQFAEQDGSFVLKFVGEVRLTLCSALDATIEKIFAALNFSAIIIDLTETQSIDSTTLGLLAKLSILSRQKVGLLPTLVTTNADITRLLQSMGFDQVFNIVDRPIPCSDCLTDLPPQDQSEEVVRGKVLEAHRILMGLNESNREAFHDLVNALERH
>NC_020829.1|WP_015477812.1|3488402_3489323_+|transaldolase
MTSKLEQLKQYTTVVADTGDFDAIARLRPVDATTNPSLLLKAAALPRYAEHLARATEGARGDAGLACDRFAVAVGKDILGVIPGRISTEVDARLSFDSEATLQRAHRLIELYDQQGIGRDRVLIKIASTWEGIRAAEQLEREGIQTNLTLLFSFAQAAACADAGVFLISPFVGRIYDWYKKANGRDYVGAEDPGVQSVSRIYRYYKANGYETVVMGASFRNLGQIEQLAGCDRLTISPDLLQQLAEAQGDLPRVLQPGGGEARQVLDESAFRWQMNEDAMGTEKLAEGIRLFARDQEKLEALLSGQ
>NC_020829.1|WP_015477823.1|3498201_3498753_-|cupredoxin-family-protein
MSLRHLFCASALAIAASFSLSALADAGHAYDFGKPGKAAQATRTVEIKLGEMYFDPENIDVKAGETVRFVIHNTGSLLHEFNLGSAAMHAGHQKEMQQMMDAGMLTPTGMQHDMSKMDHSKMGHGNMPMGQMMKHDDPNSVLVEPGKTAELTWTFSKATSLEFACNIPGHYQAGMVGKLTVKP
>NC_020829.1|WP_015477824.1|3499173_3499854_+|heavy-metal-response-regulator-transcription-factor
MKLLIVEDEPRIGQYLRQGLNEAGFAVDLCQDGDEGLQLALSGEHDLLILDVMLPGRDGWQILQAVRQTGSAVPVLFLTARDAVEDRVRGLEQGADDYLVKPFAFVELLARVRTLLRRGGQQLQETTLQLADLELDLLRRRVQRAGKRIDLTAKEFALLELLLRRSGEVLPKSLIASQVWDMNFDSDTNVIEVAIRRLRAKVDDEFPQRLIHTVRGMGYVLEERDA
>NC_020829.1|WP_041712635.1|3499853_3501167_+|heavy-metal-sensor-histidine-kinase
MAARLSLGVRLSLLFAACTAAVSLLAGIVFSRASEAHFVELDLQVMAGKLAIFRDILGNVADPAQLQPHTAELRRELERHPDLGLRLNGADGRAWFEQMPARVMPDSPPAFRELQAPLDAKAPSGPQLTLVLDITHHQHFLQRMQQLIWLTMSLSALATALLGAWAARSSLRPLRRMSEVAARVSAHSLTTRLDASQMPQELRGLAGELNAMLARLEEAFQRLSAFSADIAHELRTPLTGLLTQTQVVLSRSRDLEDYREALHGNLEELERLTAMVNDMLFLAKADHGLLAPHRQKLALAGEVDALLEFYAPLAEERGIRLERQGELQIQGDRPLLRRVLANLLDNALRFTAENGTVRVRLEPGRISVENPGREIPAERLPRLFDRFYRADPARREGQGEHAGLGLAICRSIVRAHGGDIRCESADGWTRFVIEFPR
>NC_020829.1|WP_015477826.1|3501341_3502121_-|ABC-transporter-permease
MSHELRANWVALNTIVYREVRRFLRIWPQTLLPPAITMVLYFVIFGNLIGRQIGDMGGFTYMQYIVPGLIMMSVITNSYGNVVSSFFGSKFQRNIEELLVSPVSPHTILLGFVCGGVLRGLAVGLIVTLLSLFFTDLQIHHIGITVLVVVLTAAIFSMGGFVNAVFARNFDDISIIPTFVLTPLTYLGGVFYSITLLPPFWQTVSLANPILHMVNAFRYGILGVSDIRIGTAVIFMLVATVLLYVFCIRLLVSGRGMRQ
>NC_020829.1|WP_015477827.1|3502117_3503050_-|ABC-transporter-ATP-binding-protein
MSSALSIRQLTKTYGNGFQALKGIDLDVAEGDFFALLGPNGAGKSTTIGILSTLVNKTGGTVNVFGHDLDKDPYGLKRCLGVVPQEFNFNQFEKVFDIVVTQAGYYGIPMSVAKGRAEKYLTQLGLWDKRNSASRELSGGMKRRLMIARALIHEPRLLILDEPTAGVDIELRRSMWNFLTELNQDGISIILTTHYLEEAEQLCRNIAIIDHGTIVENTSMRKLLSKLHVETFYLDLKATLSEAPKLDGYPVRLVDDHTLEVQVDKSKGINGLFAQLNAQGLEVLSLRNKSNRLEELFVSLVEKNLSKVAV
>NC_020829.1|WP_015477828.1|3503156_3503774_-|glutathione-S-transferase
MLKIWGRKNSSNVRKALWCAEEAGLAYERIDAGGAFGLVNEAPYRALNPNGVVPTLDDDGFILWESNTIVRYLAARYAPALYPQDPQQRASAEKWMDWTTSSFAGPFRTLFWGTLRTPPEQRDHAAIQAALETCAQLLDIPAQALAKQPYLSGEQFGMGDIPLGSFIYAWFEMPIERPSQPYLEAWYARLKARPAYREAVMTELT
>NC_020829.1|WP_015477829.1|3503890_3504562_-|transglutaminase-family-protein
MQEYLKPSRFVDSDHPGVIEFAENHRGQGGTPLEQAVALYYAVRDRIRYNPYVFSLDPQTLCGSHALQAGQSYCVPKATLLAACARHCGIPARIGLADVKNHLATPRLLELLRSEVFAMHGYTELFLDGRWVKATPAFDIGLCEAFGVLPLEFDGRSDSVFHPFNREGARHMEYLRSHGQFADVPEAFFFGYLQQCYPHLFAGTQEPLAGDMRAEAAKHESNR
>NC_020829.1|WP_015477830.1|3504783_3507219_+|acyl-CoA-dehydrogenase
MLLLWLLVLILGVAWLAHRRTAPLKALGLVAGYLVLMSLLSRAHGWMVLFWLLWAVAAMTILAADLRRSLFTSRLFAWFKKTLPPMSDTEREAIEAGTVWWDGQLFSGRPDWGTLLGYPRAQLTEEEQAFVDGPTEQLCALVSDHDIGQRMDLPPEAWAFIKAQGFFGLIIPKEYGGKGFSAFAHSQVVMKLASRSGDLASTVMVPNSLGPAELLLHYGTDAQRQRYLPRLASGEEIPCFALTSPQAGSDAGGMTDIGIVCKGQWNGEEVLGLRLTWEKRYITLGPVATLLGLAFKCHDPDHLLGEEEDLGITLALIPTDTPGVQIGRRHVPLGAAFMNGPNAGKDVFVPLDCIIGGADMIGKGWMMLMNCLSVGRSISLPAVGTSVAKTGSYVSGRYARIREQFNVPLAAFEGIQEALARIGGNAWMMDSARILTASAVDLGEKPSVLSAILKYHLTERGRECIAHAMDIHGGKGIIMGPNNYLGRTWQSAPIFITVEGANILSRNLMIFGQGAIRCHPYVLKEMELASRDDQDQAEREFDDLLLRHTGFAVSNAASSLLLGLGLGSFDQVPGDRVSRPYYRALNRLAAAFALLADVSMMLLGGELKRRERLSARLGDALSHLYLGSAALKRYHDLDNPEYLQPLLRWALEENLCKAEAALAGLIDNFPSRPFACLLRVLVLPLGRRHRGPGDALDAEIAAILGGPQDDPALQAILAGAFLPDDPQDPVGKLGVAYDRLAETAPLQEKLRQALRDGRIVPAAGQSPIDAARDAGVLDASEAQALHEAERARRAVIDVDDFSPEELQGKAD
>NC_020829.1|WP_015477831.1|3507347_3507767_+|hypothetical-protein
MRRSIPLLLAILLAGGAQADPWLYPSRPRPVAPPTPVIDPIQRQQDSLQRQSETRQNELDRQRLQYESQRLQLEQENLRRQQNNQRLQEQRRQLQDQVIQRQQYDQQQWRLDQQQRQLDMQQQQIDNRRRQIQSQPLRR
>NC_020829.1|WP_015477832.1|3507839_3508250_+|hypothetical-protein
MANAYLDHHLALLNHLRTILGALGEAEQVPEENHGLFLERFDELMSELPRDPEGAQYLGQDLISQVFHRYPQIAHLVPRDLLWFFGGDCLHFMPDEELQMYQQLDERRFEAEENGESFDWNREKQILALPDDAPKH

Crispr_ID: NC_020829_3

• CRISPR_ID: NC_020829_3
• CRISPR_location: 4318529-4318646
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020829_3

Consensus_repeat	Method
ACCTGTAGGAGCGAGCTTACTCGCGAAGC	CRISPRCasFinder

spacers of NC_020829_3

>3.1|4318558|60|NC_020829|CRISPRCasFinder
ACGGCACATTACCGATCGCGGACGGAGTCCGCTCCTACGCAGGCGGAAACACCGGAGCTG

CRISPR arrays and Neighbor proteins around NC_020829_3

CRISPR arrays

The CRISPR arrays of NC_020829_3

>merge|NC_020829|3|4318529-4318646|CRISPRCasFinder
ACCTGTAGGAGCGAGCTTACTCGCGAAGCACGGCACATTACCGATCGCGGACGGAGTCCGCTCCTACGCAGGCGGAAACACCGGAGCTGACCTGTAGGAGCGAGCTTGCTCGCGAAGC

>NC_020829|3|3|4318529-4318646|CRISPRCasFinder
ACCTGTAGGAGCGAGCTTACTCGCGAAGC	ACGGCACATTACCGATCGCGGACGGAGTCCGCTCCTACGCAGGCGGAAACACCGGAGCTG
ACCTGTAGGAGCGAGCTTGCTCGCGAAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020829.1|WP_015478573.1|4313890_4315417_+|ATP-dependent-RNA-helicase-RhlB	unknown	unknown	gnl|CDD|234938
NC_020829.1|WP_015478581.1|4322828_4323569_-|nitrate-reductase-molybdenum-cofactor-assembly-chaperone	unknown	unknown	gnl|CDD|225091
NC_020829.1|WP_015478580.1|4322139_4322826_-|respiratory-nitrate-reductase-subunit-gamma	unknown	unknown	gnl|CDD|376889
NC_020829.1|WP_041712154.1|4330425_4331727_-|NarK/NasA-family-nitrate-transporter	unknown	unknown	gnl|CDD|225133
NC_020829.1|WP_015478575.1|4316636_4317767_+|FAD-binding-oxidoreductase	unknown	unknown	gnl|CDD|223737
NC_020829.1|WP_015478571.1|4311555_4312494_+|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|143635
NC_020829.1|WP_015478578.1|4320111_4321098_-|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl|CDD|237364
NC_020829.1|WP_015478572.1|4312590_4313748_+|dipeptidase	unknown	unknown	gnl|CDD|238626
NC_020829.1|WP_015478576.1|4317840_4318464_+|PAS-domain-containing-protein	unknown	unknown	gnl|CDD|225512
NC_020829.1|WP_015478570.1|4309490_4311404_+|acyl-CoA-synthetase	unknown	unknown	gnl|CDD|236043
NC_020829.1|WP_015478586.1|4331900_4333763_+|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|226368
NC_020829.1|WP_015478584.1|4329009_4330413_-|NarK-family-nitrate/nitrite-MFS-transporter	unknown	unknown	gnl|CDD|184994
NC_020829.1|WP_015478574.1|4315675_4316623_+|ornithine-cyclodeaminase-family-protein	unknown	unknown	gnl|CDD|225280
NC_020829.1|WP_015478583.1|4325133_4328913_-|nitrate-reductase-subunit-alpha	unknown	unknown	gnl|CDD|227346
NC_020829.1|WP_015478568.1|4306064_4307633_-|nitrite-reductase	unknown	unknown	gnl|CDD|366994
NC_020829.1|WP_015478579.1|4321217_4322036_-|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|376360
NC_020829.1|WP_015478582.1|4323586_4325122_-|nitrate-reductase-subunit-beta	unknown	unknown	gnl|CDD|224063
NC_020829.1|WP_015478569.1|4307738_4309238_-|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl|CDD|224089
NC_020829.1|WP_015478577.1|4318745_4319522_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270421
NC_020829.1|WP_041712152.1|4305744_4306044_-|membrane-protein	unknown	unknown	gnl|CDD|225418

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020829.1|WP_015478573.1|4313890_4315417_+|ATP-dependent-RNA-helicase-RhlB	gnl|CDD|234938	PRK01297, PRK01297, ATP-dependent RNA helicase RhlB; Provisional.	0
NC_020829.1|WP_015478581.1|4322828_4323569_-|nitrate-reductase-molybdenum-cofactor-assembly-chaperone	gnl|CDD|225091	COG2180, NarJ, Nitrate reductase delta subunit [Energy production and conversion].	3.73814e-57
NC_020829.1|WP_015478580.1|4322139_4322826_-|respiratory-nitrate-reductase-subunit-gamma	gnl|CDD|376889	pfam02665, Nitrate_red_gam, Nitrate reductase gamma subunit. This family is the gamma subunit of the nitrate reductase enzyme, the gamma subunit is a b-type cytochrome that receives electrons from the quinone pool. It then transfers these via the iron-sulfur clusters of the beta subunit to the molybdenum cofactor found in the alpha subunit. The nitrate reductase enzyme, EC:1.7.99.4 catalyzes the conversion of nitrite to nitrate via the reduction of an acceptor. The nitrate reductase enzyme is composed of three subunits. Nitrate is the most widely used alternative electron acceptor after oxygen.	6.66551e-94
NC_020829.1|WP_041712154.1|4330425_4331727_-|NarK/NasA-family-nitrate-transporter	gnl|CDD|225133	COG2223, NarK, Nitrate/nitrite transporter [Inorganic ion transport and metabolism].	1.5472e-139
NC_020829.1|WP_015478575.1|4316636_4317767_+|FAD-binding-oxidoreductase	gnl|CDD|223737	COG0665, DadA, Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism].	9.27905e-58
NC_020829.1|WP_015478571.1|4311555_4312494_+|GGDEF-domain-containing-protein	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.7987e-59
NC_020829.1|WP_015478578.1|4320111_4321098_-|GTP-3',8-cyclase-MoaA	gnl|CDD|237364	PRK13361, PRK13361, GTP 3',8-cyclase MoaA.	1.27134e-177
NC_020829.1|WP_015478572.1|4312590_4313748_+|dipeptidase	gnl|CDD|238626	cd01301, rDP_like, renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics. Although the biological function of the enzyme is still unknown, it has been suggested to play a role in the renal glutathione metabolism.	3.44063e-91
NC_020829.1|WP_015478576.1|4317840_4318464_+|PAS-domain-containing-protein	gnl|CDD|225512	COG2964, COG2964, Uncharacterized protein conserved in bacteria [Function unknown].	9.85438e-77
NC_020829.1|WP_015478570.1|4309490_4311404_+|acyl-CoA-synthetase	gnl|CDD|236043	PRK07529, PRK07529, AMP-binding domain protein; Validated.	0
NC_020829.1|WP_015478586.1|4331900_4333763_+|HAMP-domain-containing-protein	gnl|CDD|226368	COG3850, NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific [Signal transduction mechanisms].	0
NC_020829.1|WP_015478584.1|4329009_4330413_-|NarK-family-nitrate/nitrite-MFS-transporter	gnl|CDD|184994	PRK15034, PRK15034, nitrate/nitrite transport protein NarU; Provisional.	0
NC_020829.1|WP_015478574.1|4315675_4316623_+|ornithine-cyclodeaminase-family-protein	gnl|CDD|225280	COG2423, COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog [Amino acid transport and metabolism].	2.65775e-70
NC_020829.1|WP_015478583.1|4325133_4328913_-|nitrate-reductase-subunit-alpha	gnl|CDD|227346	COG5013, NarG, Nitrate reductase alpha subunit [Energy production and conversion].	0
NC_020829.1|WP_015478568.1|4306064_4307633_-|nitrite-reductase	gnl|CDD|366994	pfam02239, Cytochrom_D1, Cytochrome D1 heme domain. Cytochrome cd1 (nitrite reductase) catalyzes the conversion of nitrite to nitric oxide in the nitrogen cycle. This family represents the d1 heme binding domain of cytochrome cd1, in which His/Tyr side chains ligate the d1 heme iron of the active site in the oxidized state.	1.73263e-57
NC_020829.1|WP_015478579.1|4321217_4322036_-|peptidylprolyl-isomerase	gnl|CDD|376360	pfam00639, Rotamase, PPIC-type PPIASE domain. Rotamases increase the rate of protein folding by catalyzing the interconversion of cis-proline and trans-proline.	1.46517e-29
NC_020829.1|WP_015478582.1|4323586_4325122_-|nitrate-reductase-subunit-beta	gnl|CDD|224063	COG1140, NarY, Nitrate reductase beta subunit [Energy production and conversion].	0
NC_020829.1|WP_015478569.1|4307738_4309238_-|PLP-dependent-aminotransferase-family-protein	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.15388e-121
NC_020829.1|WP_015478577.1|4318745_4319522_-|ABC-transporter-substrate-binding-protein	gnl|CDD|270421	cd13703, PBP2_HisJ_LAO, Substrate binding domain of ABC-type histidine- and lysine/arginine/ornithine transporters; the type 2 periplasmic-binding protein fold. This subgroup includes the periplasmic-binding proteins, HisJ and LAO, that serve as initial receptors in the ABC transport of histidine and lysine-arginine-ornithine amino acids. They are belong to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.42473e-121
NC_020829.1|WP_041712152.1|4305744_4306044_-|membrane-protein	gnl|CDD|225418	COG2863, COG2863, Cytochrome c553 [Energy production and conversion].	6.9365e-19

Protein sequences

>NC_020829.1|WP_015478576.1|4317840_4318464_+|PAS-domain-containing-protein
MTAADPLDNYKAIADAIATLFFPHAEVVIHDLRNQRVAYLANNISKREIGDDSALEDMLEGSSDERNIGPYEKLNWDGQKIRSISTVLRDGKGEPLAVLCINLNITLFETAKAALDLFLSSNKLIPQPDALFRDDWQERINTFLHGWLQQRQLSLSTLSRDHKRELVLALHAEGAFKGKSAANYVANVLNMGRATVYKHLKELKEEV
>NC_020829.1|WP_015478575.1|4316636_4317767_+|FAD-binding-oxidoreductase
MIEVDFLIIGGGIAGASTGYFLSRHGKVAVLEREAHAGYHSTGRSAALYTVAYGTPQVRALTAASREFFDNPPEGFAEHPILTPRGEMTVDFEGNPEELQRQYESARASVPDMRLLGADEACAIVPVLRREKVHGAMIDPSAADIDTDGLLQGYLRGIRRNGGSLHLDSEVLAIGRVDGAWEVRCTHQSYRAPVLINAAGSWCDKIAEMAGVTPLGLTPKRRAAFLFSPPEGVDSHAWPVLVSLDESFYFKPDAGMLLGSPANADPVDPHDVQPEELDIALGIYQIEEHTTLSIRRPSHTWAGLRSFFADGDLVSGFDPATPGFYWVAGQGGYGIQTSAAMGEASAALVRGETLPEHLARHGLSAEMLSPARLLQN
>NC_020829.1|WP_015478574.1|4315675_4316623_+|ornithine-cyclodeaminase-family-protein
MPAATPLTLNQAEAERLLERVDVLQAMRDMFAELAAGGAVQPAQQLVEFPNGGGDFINYLGVLASQKVYGVKTSPYIVRQPKSLVTAWSLLMSMETGQPLLLCDAGSLTIARTAATTALAVQELARPAAKRLAIIGSGPVARAHLRYAAGLRDWQSIRVYSPNLNAGVLAQFDAIDTRAEAAASVEAAVADADVVLLCTSSGTPVLDPAILTKSALITSISTNVARAHEVPPQSLAQMDVYCDYRATTPASAGEMRLARDEHNWDGALRGDLPELVSGQVAKPDYQRHAFFRSIGLGLEDVALANALYQLQRQNA
>NC_020829.1|WP_015478573.1|4313890_4315417_+|ATP-dependent-RNA-helicase-RhlB
MLKALKKIFSKGEGEQPVATPAAPAPAASEPAQSGEKRPRKPRNPRPQSESAEKPARGPKGGKPRAERSEKAERGEKTERTDKPREPRADKPRRERKPRPPVVDNWKLEDFVVEPAEGKTRFHDFNLDPRLMHAIHDLGFPYCTPIQAQVLGFTLRGQDAIGRAQTGTGKTAAFLISIITQLLQTPPPKERYMGEPRALIIAPTRELVVQIANDAIGLAKYTGLNVMSFVGGMDFDKQLRTLESRFCDILVATPGRLLDFNQRGEVHLDMVEVMVLDEADRMLDMGFIPQVRQIIRQTPYKGERQTLLFSATFTDDVMNLAKQWTVDPAIVEIEPENVASDTVEQHVYAVAGSDKYKLLYNLIAQNDWTRVMVFANRKDEVRRIEERLTKDGISAAQMSGDVPQHKRIKVLEGFREGKIRVLVATDVAGRGIHVDGISHVINFTLPEDPDDYVHRIGRTGRAGTTGTSISFAGEDDAFALPPIEELLGRKINCEMPPTELLKPVPRKH
>NC_020829.1|WP_015478572.1|4312590_4313748_+|dipeptidase
MRKILIALLLLVAVGLGIFFNLPGYFDRKMNTVAAPPPYPASDAATALHKTLFVADLHDDALLWNRNLLERHDYGHSDLPRLLEGHVGLQVFSTVTKTPRGLNYKRNGADSDNITPLIIAQRWPRATWSSLLERALYQGRMLEDAAAGSQGKLTLVRSRADLARYLAAWNKDPNQLAAVLATEGLHPLEGKLDNLDRMYDAGFRIMGLTHFFDNEVGGSAHGLQKGGLTPFGRKVIARLEDKKMLVDLAHASRALIDDVLAIATRPVLVSHTGVEGTCPGIRNLTDAHLQRIAATGGVIGIGYWDGAVCDTSVQAIVKAIRYAADKVGVEHIALGSDFDGAVHAPFDTSGLAQLTQGLAEAGFSQPDIAAIMGGNVRRLLLDTLP
>NC_020829.1|WP_015478571.1|4311555_4312494_+|GGDEF-domain-containing-protein
MKAAQWKEDIQQLQHLRLFQNVAVASLQQLLKDFRACELEAGEILLSPFNRNHFLYMVLHGQLKVYLGSLDNQPVTALNPGDCAGEISFIDNDHPSAYVVATEPTTVLRLHREALISLFQQAPQVMQNLLGVLCERVRQGNRIILDTEQNANIDTLTGLFNRRWLEHIYDRESTRCAFNEQPLCLLMLDVDHFKDYNDEHGHLAGDYALCLVAHTLRSQLRPKDSMARYGGEEFVILLPEIAVEEARRIGNRLRQSLEQIGSFYSPVGALPGVTVSLGLAQMDYLENLQSLILRADSALYQAKQEGRNRLVG
>NC_020829.1|WP_015478570.1|4309490_4311404_+|acyl-CoA-synthetase
MNAPIASLCDVQALESIPLEERNLPSSTYELLSRSAERFGPDTALSFLLQGSAAEEPLRISYAELFARVTQAANAFHRLGVRPGNSVSFLLPNLPQTHYVIWGGEAAGIVNAINPLLDPEHIAELVRAADSRVLVTLAPFLPGTGLSSGGELWDKVAALRDELPELNAIVTVDLANLLPEPQRSALKAQRGALPDGVLDFDELLAQCPDDHLESGRVIDPDEVASYFHTGGTTGTPKLAPHSHFNEVAMAEIMGLNADYDGHDVLLCGLPLFHVNGVMVTGLAPFMRGAQVLLAGPQGYRNPTLIQDFWKLVERYRVTSFSGVPTIFAALLQVPSEGHDLTSLRFALCGAAPMPVELIRQFEAKTGLKIIEGYGMTEGTCGTSCNPRGGERRPGSIGLRLPYCQLKSVILDAAGQYLRDAAVDEIGTLCLRGPTVFKGYLQASKNKDIWVDGDWFNTGDLGRIDADGYIWLTGRSKDLIIRGGHNIDPQMIEEALHRHPAVAMAAAVGKPCLKAGELPVVYIQLKPGMRASEAELLEHAAQHVPERAAVPKDVWLLDAIPVTAVGKTFKPALRLDAIRRVLEDEVRHLEPRPAVEVVADDRHGQKARLGIGRLTPDSRAALADRLGGYAIHIEWLES
>NC_020829.1|WP_015478569.1|4307738_4309238_-|PLP-dependent-aminotransferase-family-protein
MRAFQQIPLLLERGGKRSLQQQVADQLRGKVLGGVLRPGQQLPSIRELAQSLGVARNTVLLAYERLCSEGYIVTRGTRGTFVADPLPDRSLSVCRLLPRTPVGQRPDLPGFLPGMRQPLPVSPGVTPEEIRAAVELDFSLGRPSAELFPRDAWFKSSIQLARSQPRYLTDYAPSAGDPDLRAALVAHLGRARGISCSVEDVLIVSGIQEALSLVVSLFPHHHRRPVVIENPAYAGACNLFAYHRWEMLPVPVDEQGLCVGELPERPCSLVYVTPSRHYPLGMTLSLERRRALLEWAGRQGAYVLEDDYDGDFRYQRVPLPALKAFDSERVIHLGTFSKSLGASLRLGYMVCPPSLREPLVRAKALLNHACPWLPQAVLADFLTGGVYAEHLRRVRGEYRRRRDCLMAALERLFPGSRFSGVDCGMHLCWRLPPQAPPARELARACREADIWLYTLDQAAVVGPGLEALSERMLLLGYAALSLDSIADGARRIGQIAARL
>NC_020829.1|WP_015478568.1|4306064_4307633_-|nitrite-reductase
MHSFRSVSVSGLLPLVLCLAPGLAGADEPIDAARLFQENCTTCHSADRGGYIAPALNSTALNSSETALRSMIMLGIPDTLMPPWHGVLSDEQIRALAHYIKTTPRDNPQWTLQDIRDSLEVLVDESKPPDKPVYDGDVRDLMAIMQRGRYGKAPAARVVFFDGKTNKQVGEVPTDYAPHILDYDPVNPRWGYLKTDTSEIYKIDLYSLKAVRKVKAGLSGPSIAVSADGRYLLSGSFSPGIVTLFDARTLEPLSRVELRGKDYDGKQVESASSMVIASPLDNTFAIAVRQTGQVWILDPSRPQEPIVTRIEKVGRFVHDAFLSADRRYMFLADYVGNAFAVVDLKERKLVKTIAGGCQPHVGSGAITEIKGRQVAFGTNIGTCDKGDVVTVWDARTFETIKQIPVSGATESPAAHPDAPYVAVDVVSKDSRARRVELIDKNTLSVAKTIEADGHLYFPEYTRDGKYLYISGGYSGDRLHIYDSHSLEEVASYPLETPAGIFSRARTEWGTVGLQAQAKSGKP
>NC_020829.1|WP_041712152.1|4305744_4306044_-|membrane-protein
MRGLSVGAVMAALLLSGAASAADEMQALLPLCSSCHGAAGVSVAPNFPNLAGQRDVYLRKQLQDFRSGARKDPVMSPVAAGLTDAQIEAAVRYYTGQKP
>NC_020829.1|WP_015478577.1|4318745_4319522_-|ABC-transporter-substrate-binding-protein
MNRKALLGGLLLATFATFSHADDKPLRIGIEAAYPPFAYKTPEGGIAGFDYDIGNALCEQMKRKCQWIEQEYDGLIPSLKVRKIDAALSSITITDERKRSVDFTHKYYFTPGRLVMKEGSQLDEQFSQLKGKNIGVQRGSTADRFATEVLGKAGANVVRYTSQDEIYLDLVAGRLEGTFADSIPLEIGFLQTERGKGYAFIGPEFKDPKYFGEGAGIAVRKGNTELVGQLNAAIDALRANGKYKEIEGKYFKSDIYGD
>NC_020829.1|WP_015478578.1|4320111_4321098_-|GTP-3',8-cyclase-MoaA
MSEWIDGQGRKIDYLRLSVTDRCDFRCVYCMAENMRFLPRQQVLTLEEIERVARIFVERGVKKLRLTGGEPLVRPGIVHLCERLAALPGLRELCMTSNGSQLSRLAGDLYSAGLSRLNISLDTLDPQRFAAITRTGRLEQVLRGIDAAQDAGFEHIKLNCVVMKGRNADEVPALVDYAIAHGLDISFIEEMPLGQVGRAREESFCSSDEVRALIAERHELLDSAEHSGGPARYVRLAQHPGTRIGFISPHSHNFCATCNRLRLTAEGRLLLCLGHENSLDLRGLLRRHPLHDEPILDALQGALQRKPARHEFSVGDVQVLRFMNLSGG
>NC_020829.1|WP_015478579.1|4321217_4322036_-|peptidylprolyl-isomerase
MSCSHYEAKVEHVDLPKIEVNGVAIDEGELARELQYHPASSHAEALYSACRALVVRQLLVQRADALGLTADAEEGEAPEEARIRALIDREVGVPEADESSCRQWYDANPTRLTSPWRMRLRHVLLGCAPDDLEGRAKAREQAEELLAELREHPERFAEKAMRFSDCPSKDDGGDLGWIEPGQTVPEFEKRLLQQQPGLLGHPLESRYGLHVVELIERDGGEPLDFAEARPRIAAYLRAQVLQRAVSQYISVLAGEARIDGFVFDGAESPLVQ
>NC_020829.1|WP_015478580.1|4322139_4322826_-|respiratory-nitrate-reductase-subunit-gamma
MSLNLLVFGVYPYVALLICLVGSWARFDLSQYTWKAGSSQMLSKKGMRVYSNLFHVGVLFILAGHFVGLLTPHAVYEHLISTEQKQLLAMVSGGFFGVLCFIGLTGLILRRLTNDRVRATGNASDLMILLVLYVQLILGLSTIVASTHHLDGSVMVMLANWAQSIVTLQPMAAADAIAPVSLVYKLHVTLGLTLFVLFPFTRLVHIVSAPVWYFGRRYQVVRTKRRAV
>NC_020829.1|WP_015478581.1|4322828_4323569_-|nitrate-reductase-molybdenum-cofactor-assembly-chaperone
MDGHSQLLKLSALLLDYPCAELREESLALHSLIRTCDLPEAQRDGLATLLNELCRGDLLDVQARYDGLFERGRSVSLLLFEHVHGESRDRGQAMVDLMDRYTRAGLAIDVNELPDYLPLYLEFLALQDAESARVGLAEVAHILALLALRLDERDSPYAAVFHGLLELSGERPDLSALKRDRDQEVRDDSLEAIDKAWEETPVSFAEPAAGCPSSSARRISSAAEQPMQWVAQPVPQMQYRAAKVGA
>NC_020829.1|WP_015478582.1|4323586_4325122_-|nitrate-reductase-subunit-beta
MKIRSQVGMVLNLDKCIGCHTCSITCKNVWTSREGVEYAWFNNVETKPGIGYPKEWENQEKWKGGWKRNADGSIAPRIGGKFRVLANIFANPDLPEIDDYYEPFDFDYQHLHTAPKAQHQPVARPRSLISGQRMQKIEWGPNWEEILGTEFAKRRKDKNFDKVQADIYGEYENTFMMYLPRLCEHCLNPACVASCPSGAIYKREEDGIVLIDQDKCRGWRMCISGCPYKKIYFNWKSGKSEKCIFCYPRIEAGQPTVCSETCVGRIRYLGVLLYDADRIHEVATCENERDLYQKQLEIFLDPFDPKVIEQARKDGVPDSVIESAQKSPVYKLAMDWKLALPLHPEYRTLPMVWYVPPLSPIQNAAAEGHIGSDGVIPDVESLRIPVQYLANLLTAGDTAPVLLALKRLLAMRAYKRAEHVEGKQDLEVLKKVGLSVNQVEEMYRYLAIANYEDRFVIPTAHREEALSDAFAERSGCGFSFGNGCSSNSGVNLFGGKAVDKRNVIQTVQIQE
>NC_020829.1|WP_015478583.1|4325133_4328913_-|nitrate-reductase-subunit-alpha
MSYLLDRLQFFKKKQGEFADGHGEVSNESRAWENSYRQRWQHDKIVRSTHGVNCTGSCSWKIYVKNGLITWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYIYSANRLKYPKVRKPLLKLWREARTTHNDPVDAWASIVEDSAKAKSYKSERGLGGFVRSSWNEVTEIIAAANVYTAKVYGPDRVVGFSPIPAMSMVSYAAGARYLSLIGGVCLSFYDWYCDLPPASPQIWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTVSVTPDYSEVAKLTDLWLNPKQGTDAALGMAFGHVILKEFHLEKPSAYFVDYCRQYTDMPMLVLLEPHTDGVLKPTRYLRAADLANNLGQDNNPEWKTIGLDEISGELVSPTGTIGYRWGESGKWNIEEKEGGEKRDTRLALTLIDGPEKACDVAFPYFAGQEHPHFKGVDNDEVLVRRVPFREVTGADGKTLRVATVYDLQMANYSVDRGLGGANVAASYTDADVPYTPAWQARITGVPAARAIQVAREFADSADKTRGKAMVIIGAAMNHWYHMDMNYRAVINMLMMCGCIGQSGGGWAHYVGQEKLRPQTGWVPLAFGTDWSRPPRQMNGTSFFYLHSSQWRHEKISMHEVLSPLADTKQFPEHALDYNIRAERMGWLPSAPQLNRNPLHIAADAERAGIPVQDYVVRELKAGNLRVASEAPDDPQNFPRNMFIWRSNLLGSSGKGHEYMLKYLLGTKNGVMNDDLGKAGGPCPGEVDWVDQGAEGKLDLVTTLDFRMSSTCMYSDIVLPTATWYEKDDLNTSDMHPFIHPLSAATDPAWEAKSDWEIYKAIAKKFSEVSVGHLGVEKDLVTVPLLHDTANELAQPFGGSDWKKGECEPMPGKTMPTLHVVERDYPNTYKKFTSLGPLLDKLGNGGKGIGWNTDKEIKLLGELNHKVTETGISEGRPRIESAIDAAEVILALAPETNGQVAVKAWDALSVFTGREHAHLALPKEEEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNVHEMIPWRTITGRQQFYQDHPWMQAFGEGFVSYRPPVNTRSTDKLFNKKPNGNTEITLNWITPHQKWGIHSTYTDNLLMLTLSRGGPIIWMSENDAKRAGIEDNDWVEVFNANGAATCRAVVSQRVKDGMVMMYHAQERIVNLPGSETTGTRGGHHNSVTRVVLKPTHMIGGYAQQAWGFNYYGTVGCNRDEFVVVRKMNKVDWLDEPEHGGLGGDALPQPLPQDI
>NC_020829.1|WP_015478584.1|4329009_4330413_-|NarK-family-nitrate/nitrite-MFS-transporter
MGMMNTQLKAASGPLLIDWRPEDSEFWARSGKRIAARNLWISIPALLLAFAVWMIWSTVTVRLNAAGFSFSNDQLFLLAALPSISGATLRVFYSFMVPMVGGRRWTALSTASLLIPCIWLGFAVQDPTTPYWVFATIALLCGFGGGNFASSMSNISFFYPKNQQGTALGLNAGLGNLGVSVMQFAVPLAVAGGLFGAFGGEPQQLSDGGRLFLQNAGWIWVPFIAVVSIAAWFGMNDIADAKASFREQSVIFKRKHNWLMCWLYVATFGSFIGFSAGFAMLSKTQFPDINPLQYAFLGPLVGALSRPLGGWLADKFGGARITLWNYAAMIAGVFAVISFLPSAGNAGSFFGFLGSFIGLFFFAGIGNGSTFRMIPVIFRNEWAARLKRGGFTEAQATKNASMESAAVIGFSAAIGAFGGFFIPKAFGTSLDMTGSAEGALYVFVAYYLSCIVATWWWYARKGAESPC
>NC_020829.1|WP_041712154.1|4330425_4331727_-|NarK/NasA-family-nitrate-transporter
MLSHRQKQYSVLGMSTLAFAVNFAVWTMFSIIGIRIKEELGLSEAQFGLMVALPILTGSLVRLPLGLITDRFGGRIVFFIHMLLVAIPIYGLAFATLYWHYLVLGLFVGLAGGSFAVGIAYTSSWFEKERQGTAMGIFGAGNAGAAITNLVAPMIVVAFGWRMVPQIYSVAMLVTALLFWFCTWTDPAHTKGGDADPGRPRPTLAKQLAPLGELRVWRFGLYYFFVFGGFVALALWLPKYYIAEYGLDLRTASFITMLFTLPSGLIRALGGWFSDHYGARAVNWGVFWICLVCLFFLSYPPTTMTIHGIKGDVSLGIGLNVWLFTFLVFVVGIAQGFGKASVYRIIHDYYPQNMGTVGGMVGVIGGLGGFCLPILFGYAADHIGVRSSCFMLLFGLTVICMVWMHYAIKQQQRLDGQAQAADVDATPIPFSQS
>NC_020829.1|WP_015478586.1|4331900_4333763_+|HAMP-domain-containing-protein
MNTAPSTEPSANDRIFVGSPPASRTALRKSIVVRFGCYLTLLVSLALAGMFSALLFADYSHQDAAVINQAGSLRMLTYRLALDPSPINRQALQSTLAARLDNDEITRLLRRSDVDAPIRQQHDQLRQELNKLDLSQEPTLSTLDTFVSHIDAFVGTLQNNAEQRSQMLSTVQGLCLFLSLLVVFISLYDLSYHVVGPLRDLTSTARRLGEGDLSARVSSSGEDELSQLGERFNQMATELQAIYRELEARVEDKTRDLSNSHQRLELLYASARRLGQDPYDERTLQPLLNQLERVLQGGKVTLCLNKDGVERAYTSLTTDGITGSFCLQGNCGDCRAQAAHCGEPSRGINPLLMQPLTIGEHRFGELFIETTSGRLEDWQRQFVEGFCDNIARTFALSLQQEQENRLALFAERSTIARELHDSLAQSLSYLKIQVSRLATLLKRDVPPQKIEETLDELREGLNSAYRQLRELLTTFRLSLEQSSLEAALVKTVEEFGERGDLSIELDNRLAHIPLNPNEEIHILQIVREALSNVVRHAQASHAKVSLAEDADDQVCITIDDDGVGFDPAQSRNGHYGLSIMRERSQTLEATFTIVPREPLGTRVSVRFTHKPLSQHPENPS

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	935654 : 978058	28	Moraxella_phage(14.29%)	tRNA,transposase,holin	NA
DBSCAN-SWA_2	1680390 : 1688193	7	Bacillus_phage(33.33%)	NA	NA
DBSCAN-SWA_3	3069715 : 3077725	10	uncultured_Caudovirales_phage(85.71%)	tRNA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_020829|935654:978058|DBSCAN-SWA
TTCAGCGTCGGGTCAGCAGGACGCCGGCTTCCATGTGGTGCGTATAGGGGAACTGGTCGAACAGCGCGCAGCGGCTCACCTGGTGGGTGTCGTGCAGCTGGGCGATGTTCTGCGCCAGGGTCTCCGGGTTGCAGGAGATGTACAGGATGTTGTCGAAGCGCCGGGTCAGCTCGCAGGTGTCCGGGTCCATGCCGGCGCGCGGCGGGTCGACGAACACGCTGCCGAACGCGTAGGACTTCAGGTCGACGTCGGCCAGACGGCGGAACGGGCGTACGTCATTCAGCGCCTGGGTCAGCTCCTCGGCGGAGAGGCGTACCAGGGTGACGTTGTCCACGGCGTTGTCGGCCAGGTTGGCCAGGGCGGCGTTCACCGAGGTCTTGCTGATCTCGGTGGCCAGCACCTTGCGCACGCGGGTCGCCAGCGGCAGGGTGAAGTTGCCGTTGCCGCAGTACAGCTCCAGCAGGTCGTCCTCGCGCTGGCCCAGGGCTTCGTACGCCCAGTTGAGCATCTTCTGGCAGACCTCGCCGTTGGGCTGGGTGAAGGCGCCCTCCGGCTGGCGGTAGCGGAAGGTGCGGCCGGCGACGGTCAGTTCTTCGCTCACGTAGTCACGGCCGACGACCAGGCGCTTGCCGCGCGAGCGGCCGACGATGCTCACGCCCAGCTCGGCGGCCAGCTTCTCGGCGGCGGCCTGCCAGGCCGCGTCCACCGGGCGGTGGTAGCACAGGGTGATCATGGCGTCGCCCGCCAGGGTGGTGAGGAACTCCACCTGGAACAGCTTGTGGCCCAGGGTCGGCTCGGCCCAGGCAGCCTTCAGGCGCGGCATCAGTTCGTTGATGCGCTGGCTGGCGATGGGGAATTCCTCGATCAGGATCGGCGTGTGCTTGTCGCCCTGCTCGAACATCGCGTAGTGGCGGGCTTCGCCCTCGCGCCACAGGCGGAACTCGGCGCGCAGGCGGTAATGCTCGCGGGGCGAATCGAACACCTCCGGCTCCGGCGCGGCGAAGGGCGCCAGCAGCTCGCGCAGGCGCGCGGCCTTTTCGGCCAGTTGGCTGTCGTATTGGGAGGGATCGAAACGCGGGCTGCTCATGGGGATAACTCTTCAAAGGGGCCCGGATTCGCTGGGCCGCTTTTCAATTAGGGACAACTCGAAACTATCGGGGCTCGCGAGCCAGGTCAGACAAGGCGCTAGGTCGATTCGAAAGCGGAGGGTAAATAAGCATTTCGGATTGACCTGGCAACGCAGTATGGCCGACGCGCAGCAGCCCCCTTCACTCAAGCGTTGAACCAGCCCAGCTTGATCACGAACAGAATCGATAGGATGACCAGCGCCGGGTTCAGCTCGCGGAAGCGGCCGGACAGCAGCTTGCAGGCGGTCCAGGTGATGAAGCCGAAGGCGATGCCGTTGGCGATGGAGAAGGTCAGCGGCATGGCCAGGGCGGTCACCACCACCGGAGCGGCGACGGTCAGGTCGTCCCAGTCGATCTCGGCGAGGCCCGAAGCCATCAGCACGGCGACGAAGAACAGTGCCGGTGCGGTGGCGAACGCCGGCACGTTGCCCGCCAGCGGGGCGAAGAACAGCGCCAGCAGGAACAGCACGGCGACCACGATGGCGGTCAGGCCGGTGCGGCCGCCAGCGGAAACGCCCGCCGCCGACTCGATGTAGCTGGTGGTGGTGGAGGTGCCCAGCAGCGAACCGACCATGGCGGCGGAGCTGTCGGCGATCAGGGCACGGCCCATCTTCGGCATGTGCCCGTCCTTGCCCATCAGGCCGGCGCGCTTGGCCACGCCGATCAGGGTGCCGGAGTTGTCGAACAGGTCGACGAAGAGGAAGGCGAAGATCACGCTGAACAGGCCGATGTCCAGCGCGCCCTTGATATCCAGCTGCAGGAAGGTCGGCGCCAGCGACGGCGGCATCGATACCACGCCACCGAACTGGGAGACGCCGATGGCGATGGAGATGAAGGTCACCGCCAGGATGCCGATCATCACCGCGCCGGTCACGCGACGGGCTTCCAGGGCGACGATCAGGATGAAGCCGAGGATCGCCAGCAGCGGCGCCGGCTTGGCCAGGTCGCCCATGCCCACCAGGGTGGCCTGGTTGGCGACGACGATGCCCGATTCCTTCAGCGCGATCAGCGCGAGGAACAGGCCGATGCCGGCGGCGATCGCCGAGCGCAGCGCCAGCGGGATGCTGTTGATGATCCACTCGCGGACACGGAAGATCGAAATGACGAAGAACATGCACGCGGAGAGAAACACCGCGCCGAGCGCCACCTGCCAGGTGTGGCCCATGTGCAGGACCACGGTGTAGGTGAAGAAGGCGTTCAGGCCCATGCCGGGCGCCAGGGCGATCGGGTAGTTGGCGATCAGGCCCATCACCGCCGAACCGATGGCGGCGGCCAGGCAGGTGGCGACGAAGATCGCACCCTTGTCCATGCCCGTCTCGCCGAGGATGCTCGGGTTGACGAAGAGGATGTAGGCCATCGTCAGGAAGGTGGTGATACCCGCCAGGATCTCGGTGCGCACGTTGGTATTGTGCGCCTTGAGTTGGAACAGCTTTTCCAGCATGTTTGGCTCCCCGTGACGCTGCTCGCGCCGTTGTCGTTCTGGCCGGGAAAAGCAAGGTGCATGCCCAGGTGGGCTGTGCGCCTTTTCTTGTGACCGGCAAAAGGCGCGCATGATACCAGCTCGTCCCGCGCCGGAGAATTTCTGACCGGACCGCCAGCATCCGTTCGTCTGCAAGCTTAGTCGCGGCTGCCGACCAAGGGAGTGCAACTTGTGCCACAACAGTGGTCTGACTCTCTATGACCCCGGCCTGACCGGCCCTTCCGCTTGATTCGCATTCGATGAAACGCTCTATACCGTTCCTTTTCGCATCGCTGCTGGCCGCTTGTGCCGGCGAACCGCCGACCATCCCGCAGCACAGTTTCGATGTCCACACCCTGGCCGAGCGCCCCTCGGCCAGCACTCGCACCCTGGCCGACCCGCAGGGCAAGGCGGTGCTGGTGACGACCCAGCCGACCCTGACCCAGCACGACGTGCAGCAGGCCCAGCTGGCCAGCGTTGCCGACGGCAAGCCTGCCGTGCAGGTGCAGTTCACCCCCGACGCCAGCCTGCGCCTCGCGCACCTGACCCGAGAGGCGCAGGGCAAGGCGCTGGCGGTGGTGATCGACGGGCAGTTGCGCCTGTTGCCGAAGGTCGACCACCCGCTGACCGATGGCCGCGTGCTGCTCCAGGGCTTCGCCAGCCAGGTGGAGGCCGAGACGCTGGTGCGCCGGCTCAACGAACTGCGTGATGTGCCGGTGCAGCCGGAGCAGAAGTCCGGCGGACAGCCATAGCGCTCCATAGAAAGGCAGGGTGGTGCTTCGTAGGAGCGAGCTTGCTCGCGAACCCCACAACCCGGTACCCAGCTGGAATCCGTTCGCGAGCAAGCTCGCTCCTACAGATCGGACCTGCCTCCTCGGTGTGGCGCCCATGAAAAAGCCCGGCATCTGCCGGGCTTTTTCGACTCGCGGTTCGGGCTTAGGCGCCGTACACCGGGAACTTGGCGCAGATGGCCTTGACCTTCTCGCGCACGCCGTCCACCACGGACTCGTCGCCCATGTTGGTCAGGATGTCGCAGATCCAGCCGGCCAGCTCGCGGCACTCGGCTTCCTTGAAGCCGCGGGTGGTCACGGCGGGGGTGCCGATGCGCAGGCCGGAGGTGACGAACGGGGAACGCGGATCGTTCGGCACGCTGTTCTTGTTCACGGTGATGAAGGCACGACCCAGGGCGGCGTCGGCGTCCTTACCGGTGATGTCCTGCTTGATCAGGGACAGCAGGAACAGGTGGTTCTGGGTACCGCCGGAAACCACGTCGAAGCCGCGCTCGATGAACACGCTGGCCATGGTCTGGGCGTTCTTCAGGACCTGCTGCTGGTAGGCCTTGAACTCGGGCTGCAGGGCCTCCTTGAAGCACACGGCCTTGGCGGCGATCACATGCTCCAGCGGGCCACCCTGGGCGCCCGGGAAGACGGCGGAGTTCAGCTTCTTCTCGATCTCTTCGTTCTTGCGAGCGAGGATCAGGCCGCCGCGCGGGCCGCGCAGGGTCTTGTGGGTGGTGGTGGTGACCACGTCGGCGAACGGTACCGGGTTCGGGTAGACGCCAGCGGCGACCAGACCGGCCACGTGGGCCATGTCGACGAACAGGTAGGCACCGACCTTGTCCGCGATGGCGCGGAAGCGGGCGAAGTCCAGCACCTGGGAGTAGGCGGAGAAGCCGGCGACGATCATCTTCGGCTTGTGCTCGACGGCCAGGCGCTCGACTTCGTCGTAGTCGATCAGGCCGGCGTCGGTGATGCCGTACTGAACGGCGTTGTACAGCTTGCCGGAGGAGGAGACGCTGGCGCCGTGGGTCAGGTGACCGCCGTGGGCCAGGCTCATGCCCAGGATGGTGTCACCGGCCGACAGCAGGGCCAGGTAGACGGCGGCGTTGGCCTGGGAGCCGGCGTGCGGCTGGACGTTGGCGTAGTCGGCGCCGAACAGTTGCTTGGCGCGGTCGATGGCGAGTTGCTCGACAACGTCGACGTACTCGCAACCACCGTAGTAGCGCTTGCCCGGGTAGCCTTCGGCGTACTTGTTGGTCAGCACCGAACCCTGGGCTTCCATCACCGCCGGGCTGGTGTAGTTCTCGGAGGCGATGAGCTCGATGTGCTCTTCCTGGCGCTGGGCTTCCTGCTCCATCGCGGCGAAGAGTTCGGCATCGTAGCGGGCGAGGGTCAAATCACGGCTGAACATGGCGGTCCTCTTAAGGATCGGGTGCTGGGGAAAGGCGCGCATTCTAACCCAAGGCGCCGGTGCTGGCACATGAAAGGCGGTCATGTGGCTGACAAGCGGGGTTCAAGGCCTGGAAGTGTGCGGAATTGCGAGCGGTTTGGCACCGACGGTGGGCCGGGTGTGTAGCGGACTCCGTCCGCGATGTGCCACCGGCCGGCTCGGAGCCGCCGGGAATTGATCACGGACGGAGACGCATAGCCAAGCATCGCGCGGGTGCGTGCGATCAGCCGAGCAGGAACAGCGCATTGCTGGCGAACAGCGCGGCGAACTGGCCGGCCGGCACCGGGCGGCCGAAGAGGAAGCCCTGCACCTCGTCGCAGCCGTGCTGGCGCAGGAACTCCAACTGCTCGTGGCTCTCCACGCCTTCGGCGATCACCATCAGGTTCAGGCTGTGGGCCATGGCGATGATGGCGCGGGCGATCTGCGCGTCCTGCTCGCCGTGGGGCAGGCCGTCGACGAAGCTGCGGTCGATCTTCAGCACGTCGATGGGGAACTGCTTGAGGTAGTTGAGCGAGGAGTAGCCGGTGCCGAAGTCGTCCACCGCGATGGCCAGGCCCAGGCGTTTCAGCCCGGAGAGGATCTGCATGGCCTGGGACACGTCGCTCATCAGGATGCTTTCGGTCAGCTCCAGCTCCAGGCAGGCCGGCGGGATGCCGGTGTCCTTGAGGATGCCGGCGATGCGCTCGCCGAGCTGGCCGTCGGCGAACTGCCGGGCGGAGAGGTTCACCGAAACCTTCGGCACCCGCACCTTGTCGCGGTGCCAGGCCTTGAGTTGCAGGCAGGCCTGTTCCAGCAGCCAGTCGCCGACCTGGGCCACCAGCCCGAGCTCTTCCAGGACCGGGACGAACTCCGCCGGCGGGATCAGCCCGCGCTTGGGGTGCTGCCAGCGCAGCAGGGCCTCGGCGCCGGTCAGGCGGCGGCCGTCGCCGGTGAACTGCGGCTGGTAATGCAGGATGAACTCCTCCTGCTCGATGGCGCGGCGCAGGTCGCTTTCCAGCTCCAGGCGCTCCAGGGCGCGGGCGTTCATCTCGGCCTGGTAGAACTGGAAGTTGTTCTTGCCCATCTCCTTGGCGTGGTACATCGCCGTGTCGGCGTTCTTCATCAGTTGGCTGAGCTCGGCGCCGTCCTGCGGCGAGAGCGCCACGCCGATGCTGGCGGTGACGAAGAATTCGCGGCCTTCGAGGGTGAAGGGGCGGGCCAGGCTGGCGAGGATCTGCTCGGCCACCTGGATCGCCTGGCGCAGTGCCCGTTCGCGGTCGGCCTGGCCGGGCAGCAGCAGGGTGAACTCGTCGCCGCCCATGCGCGCCACGGTGTCGTCGTCGCTGACGCAGTGGCTCAGGCGCTCGGCCACCTCCTTGAGCATGCGGTCGCCGGCGGCGTGGCCCAGGGAGTCGTTGATCGGCTTGAAGCGGTCGAGGTCGAGGAACATCAGCACCACCCACTGCTGGTGCCGTTCGGCCTGCAGCAGCGCGGTGTGCAGGCGGTCCTGGAACAGCGTGCGGTTGGGCAGGTGGGTCAGGGCGTCGTAGTAGGCCAGGCGGTGGATGCGCCGTTCGCTGGCCTTGCGCTCGCTGATGTCGCTGAAGAAGCAGACGAAACTGACCAGGTCGCCTTCCTCGTCGTGCACGGCGGTGATGCCGACCCAGGACGGGTACAGCTCGCCGTTCTTGCGCTTCTGCAGGATCTCGCCTTCCCAGCTGCCGCTCTTGCGCAGGCTGTCCAGCACATGCTTGAGCTGGTTGGCCTCCTGGCGGTCGGCGGTGAGCAGGCGCGGCAACTGGTCCAGCACTTCCTCGGCGCAGTAGCCGGTGAGGCGGCTGAAGGAGTCGTTGATCTGCACGATGTAGCCGGCCGGGTCGGTGACCATGATGGCTGCCGTGGAGTGCTCGAACACCGTGGCGGCCATGCGCATCTCGCGTTCGGCACGGCGCTGCTGGCTGATGTCGCGGGCGACGCCGAGCAGGCCCTCGAAGCAGCCGTGATCGTCCCACATCAGGGCGATGCGCAGTTCCACCGGAATCTTGTGGCCGTCGGCGTGTATGCAGTCGAGAGTGAACAACTGCGGCTCGGTGTTCTCGCGCAGCTCGGCGAGGCGCGTGGGCTCGCCGATGGCGTCGTGCAGCCGCTCCAGCAGCGCGGTGAGGCGTTCCAGCTGCGCCGGGTTGGCGGCCACTTGCTGGAAACCGTTCTGCCGCACCCATTCGGCGTTGTAGCCGAACACCTGCTGGATCGACGGGCTGACGTAGTTGAGCCTGACCTGGGCGTCGGTGGAGACGATCACGTCGCTGATACTCTCGGCCAGCATCCGATAGCGGCGCCCGCTCTCGCGCAGGGAGTTGTGTGCCTCGACGGTGCCGGTGATGTCCTTGGCCACGCCGATCAGCCGCGCCACGCGGCCAGCGGCGTCGCGGGTGAAGGCTTGTTCGCGGATGTCGAACCAGTGCCAGCTGCCGTCGCGGTGGCGCCAGCGCAACTGGCTGTCGAGCAGCAGGCCATCGCCCACCACTTGCTGCAGGTTGCGCACGCGCCAGTAGTACTCGGCGTCGTCCGGGTGCAGCACCTTTTCCCAGAAGCGCTCGCCCATCGCGCGCAGCTCGTCGCCGTTGTAGCCGAGCTGGTGGCCGAGGTTGTGGTTGCTGAAGATTACCCGGCGCGCGGCGATGTCGTGGATGTACAGGGTGTCGGGCACCGCGCGGACCGCGTCGGACCAGAACTTCTCGCGCTCGACCAGCGACAGTTCGACCTGCTTGCGCGAGGTGATGTCGGAGAGGCTCAGGGTGACGGCGTGGAAGTCCTGGATCATCTCCGGCACGCGCAGTTGCAGCCAGAGGTGGCGCTGCTCACCCTGGCGCGTGCGGATGCAGGCTTCCAGCTCGATCATGCCGTGGCCGGCCAGGACCGCGTCGAGCACCTTGCTGCGCACACCGTCCGGGCGCATACCGGCGCTGCCGAGGAGAATCTGCCAGGCCTGTTCGGTGGTGCTGATGCCCATCAGGCGCTTGGCGACGTTGTTGATCTCGGTGATGCGCACCTGGCGCAGCAGTTGGGGCAGGTGCTCGGGATGCGCGGCGATCCACGCCTGCAGATCGCTCTGCCGGCGCAGGTTGAGGTCCACCAGGCTCTGCCGCAGTGCCGACAGGTCGAGCACGCAGAGGGCGACGCCGACGCCGTCGAAGATGTCCTGGTAGCGCCGCCGCGTCTCTTCGAGGATGTGCAGCGCCTGCTGTTCCTCGGTGACGTCGCGCAGCACCCAGACCTGGTCGCCTTGCGGTGGATCGCCGCGCAGCAGCCACGGCAGGTCCGGGAGGTGGAGCGTGTCGTCCAGCGGACGCCGGCTGACCGCGAACAGGCGCGGCTGCCCCGTGTGGATGACCCGGACCAGCTCGGTGCCGCCGCTGTCCGGCAGGTTGGCGTCGCCATTGAGCTGTGCGCCCAGTCCCGGCAGGAGTTCCAGCAGGTGATGGTGGTGGGCCTGGTCGGCCTGGATGCCGAACAACTGCTCGGCCTGCGGATTGAGGTAGGCGAGGCGGCCGTCGGCGCGGGTCACCAGCACCCGTTCGTCGATGGCGCCCAGTGCCTGGGCGGCCTGGCGCAGGCGTTGCCGGGAGTCGGCGGTCAGCGCGCGCAGGTTCTGTTGCTCTCGTTGCAGGCGCAGCAGGGCGCCTCCGGTGACACCGGCGAGCAACAGCAGCAGCGCCAGTTCCCCGCTCAGGCGCGGCAGCAGCGCGGCGCGCACGCGCTGGACGTCGAACAGCGGGCGCAGTTGCCAGTCGGTGTTCTTGATCGGCAGCCCGTCGAGGCTCTGTGCCTGTTCCAGTGGCGAAGCGGCGCTGAGCGGGCCGGGGCGGGAACCGCTGGAGCGGCCCAGGACCTTCTTGCGCACCTGGTCTTCGAGGATCCACGGCGGCGTGTCGGGGCGAACCTGCGCGAGCCAGCCGCGGCGGGCGAGCTTCTCGTCCAGACGAATGATGCTGTCGCCTTCGCCGGGCGCAGTGGCCCGCAGCCAGACGTAGAACACGCCGCCCTTGTCTTCGCTGAAGGCGTAGTGATAGTCCTGCTGTCCGCCGCGCTGGCGCAGGGTGGCGATGGCGGCGGCATCCTTGAAGCCGATGGCGGAGTCGCTCCGGGCGCGGCCATTGCGCTCCAGGCGCACCAGGCTGTGGAAGGCGGGATAGATGCGACGCAGACAGATGAGCAGGGCAGGTTCGCCTTCGACGTCGCCACGCTCGTCGCGTTGCTGAAGCAGGGCCTGCGCGGCCAGCGCCTTCAGCTCGAGGGTCAGCGACATGCGCTGGGCCAGTTGCTCGCTGTGCAGCACCACGCGCTCGCGCTCGAAGCTCTCCTGGCTGCGGAACTCCTGGTACAGCCGCCAGAACAGCAGGCCGAGCATCAGCAGGACTAGCAGCAACAGGGCGGTCCGGGTTGCCACGCGGCCAGGCCTGGCCAGGGAGTCCGGGGAAGGGCGGGGTGTTGTAGACAAGGACCTGTTACCTGGCGGCGATACGGCGGGATTCGGCGCAGCTAGGATGCCCGGAAGCTGGGCGATGTGCCAGTATCGCCGACGAGCGTCGTTTGCCCTTCCTGGCCCATTCCGGTAGCTTTGCCGCACGCGCGCGGGTGAAATCACCGCGCCACGCCTAGCGCGAAGGCCCTGAACCGGCCCTCCGCGCCCGCCGGTGGGGGCACTCCACCGTATCCGGCCAGCAGCGCCGGCGATCCGGAACCTGCCGCAGTTCGTTCCGGCCCATTCCGATCACTTTTCATCCCAGAAGTCAGGTATCCATGGCTCAATAGGCTTCTCTACCCTATTAGGGTTTAGTCAGGTTTTGCGATCTGCGGTCTAGCCTGCATGTCCGCTGGCTTTCCAGCCCTCTTAGCATCATTCCCCTCTCAATCCTGTGTCAGCGCATGGATTTTTAGTTAGGTTTCGCTGGTTTTGGGTCAAGTTTAGGCTCCAAAACTTAACTTTTTGTAAGTGTTCCCGTGATCTCTTCCTGTCAGGTATCGCCAGCCGATTTCCTGTTGTGAGGCAGCAAATAAGGTTCTTCTTATAACAAGAAACTCATCATTTCTCAGGGCATCTACAAGCCCGGTTTCCGAAGACGCTATTGAGAAAATTCCAGCGGTGCAGGTGAAGTGATCACTGACGTCTAGGTTAGACTCGCGTCTTTGCGTGACTTTCAAGGGCGAGTACAACCCGCGTCTGGATCTGGTGCTGTTCGTCAACGGTATCCCCACCGCCACGCTGGAGCTGAAAAGCGAGTTCAAGCAGAGCGTGGAAAACGCCAAGCGCCAGTACCGCCAGGATCGCCCGGTCAAAGACCCGCTGACGCGCAAACCCGAGCCGCTGCTGACCTTCAAGCGTGGCGCGCTGGTGCACTTTGCCGTGAGCCAGGATGAAGTGGCGATGACCACCAAGCTGGCCGGCAAGGAGACCTTCTTTCTGCCGTTCAACCTCGGCAGTCTCGACGGCGGTGCTGGCAACCCGCCTGCGCCGGATGACAGCCATTACGTCACCGGCTACCTGTGGCAGCGTTTGTTCCAGCCTGATGCCTGGCTGAGGGTGCTGGGCCGCTTCCTGCACCTGCAGAAGAGCGGAAAAGAGGATGCCGATGGCGATCGCATCACCAAGGAAACCCTGATCTTCCCGCGCTACCACCAGTGGAAGTGGTCAACACGCTGATCGACACCACCCGCGCCGAAGGGCCGGGCAAGCGTTACCTGATCCAGCACAGCGCCGGCTCCGGCAAGTCCAACTCGATTGCCTGGACGGCTCACCAACTGGCCTCGCTCTACGATGCCGAGGGGCAACGGCTGTTCAACTCGGTGATCGTGATTACCGACCGCACCGTGCTGGACAAGCAGCTGCAGGACACCATCTACCAGTTCGAGCATGCCCAGGGCGTGGTCAAGTGCATCACCCGCGATATCGGCAACCAGAGCAAGTCCGAGCAGCTGGCCGAGGCGCTGGCCGAGCAGACGCGCATCATCATCGTCACCATCCAGACCTTCCCGGCGCTGTTCGATGCGCTGGACAAGCACCCCAAGCTGGCCAGCGGGCGCTATGCGGTGATCGCCGATGAAGCGCATTCCTCGCAGACCGGCTCATCGGCCAGCAAGCTGAAGCAGATTCTCGGCAGCGATGCCCCGGACGCCGAAGAGATCAGCGCCGAAGAACTGGACGCCGCCGTGGCTGCGCGTGCGCCCAACGAACGCATCAGCTACTACGCCTTTACCGCCACGCCCAAGCCCAAGACCCTGGAGCTGTTTGGCCGCCCGGCCAATCCGGCGTTGCCAGTGAGCGCCGACAACAAGCCTGAGGCGTTCCACCTGTACTCCATGCGCCAGGCCATCGAGGAGGGTATCTATCACTGGGAGGAGGTGGCTGCGTTCGCCATCGCTTTCTTCGACCCCAAGGCAACTGCCAGCAAGCTCAGCTACTACTGCGCGCCGGCTAAGGAGCGCTTTGCCAAGCGCTACAAGCTGGCCCAGGAATCACGCCAGCATGCGCTGGACTTCAAGCGTACCGCCGAACAAAACGGCGACAGCGCCGGTGTGAAGAAGGCCGAGGCGGCAATCAAGGAAGCCGGCGAGCAGGTTGATCAGCTCGATCTATTCAAGAAGAACTTGCAGAGCTTTGTCCGCCTGTACGAGTTCCTCTCGCAAATCATTCCCTATGAGGATCGAGAGCTGGAGCAACTGTGCGTGTACGCCAAGCACCTGCATCCGCTGCTCCGAGTGGATCGTCTGGAGCAGGAAGACGTTGACCTGGGCGAGTTGCAGCTGAGCCACTACCGCCTGAGTAAGCGGGCCGAGCATCAACTTCGGCTGAGCGAAGAGAAAGGCGACTATGGCCTTGACCCGGCCAGCGCGGTCGGCAGCGGCAAAGCCCATGATCCCGAGAAGAAGCGGTTGTCAGAGATTATCGAGGCGCTCAACGATATTTTCGGGGCAGAAGTCAGTGATGAAGACCAACTGCAATTCCTCACTGGTATGGCCAAACGCATCAGCCGCCAGGAGGATGTGATGGCCCAGGTAAACAACCACTCGGTTGAACAGGTGATGCATGGCCTGTTCCCCAAACGCGTTCTGGACACCGTGCTGGACGCCATGACCGACCACGAGAAGCTGTCGCTGGAAGTACTGGACAACGAGACCAAGAGCCGGGCGTTTGCATTGGTAATTTTGAAGATGCTGACGGCGGCTGGTGGTTGGGGCAAAGTAATAGTGGCTCTGCGGTCTGACCTTCTTGCGCGCCGGTATTACGTACTCGGGCTAAATTTCAGACGGCTTCGGCAAAAGACTTGAGGGGTCGCAGGCGAGCTCGCCTGCGATGCGGTAGAGCTTCTCGACGGTGATGTTGACCTCGCCACGCTCGATCCGCCCCATGTAGCTGCGGTCGATACTGCAGGCCAATGCTAGAGCATCCTGAGAAATCCGGCAGACCTTCCTCTGCGACCGGATGCGTTCCCCTAACGCTTTCGCCAAGTTGTCCATGACCGTCTCAATTTCACTTGAGGCGGCACTATCGTGCGTTTGCGGATGCGCCAGCCACGGATTATAATCCGCATTTCTGTCGCGTTAGCCCTTCTGGTTCCTCAATGAAAACGGCCTCGTTTACCTTCGACAGGCGTCTGTATGAGCTGCTTCAGGAGGAAGCGCGTGCAAGGTTCACGACTCGTGAACTGCGTGATGCCTACGCCAAGCGCCTGGATGGCGTGAATTTCCGTATCAGCGATGTGCGCCGCTATGTGTATGAGCAGATCCGCCGCATGCTGCGCATGGGCTGGGTTGTACATGATGAGGAGCGACGTTCGCGGGGACAGGTATACCGCCTGCAACCCAAGCCGGTCCATCTGCAGCTGGAGCTGATCGATGACGGGTTCGAGAAAAGTTTCAAAACTGCATCTGAGCCAACGCAGGAGTCGTCAGTGCAGGATCATGCGGCTGTACCGCTTGAGCCGTCATCCGACGCGGAGCAGCACTTGGAAGCGCTCCATAATGAGATCCGGTTGGACTTCCTGTCGTCGATGGGCGAGGCGGAGCGATACAAGCTGCTCCTGGGTGATATGCCGCATCTGCGTGACAAGGTCGAAGCCGAGTATCTGGAGGCTAGAGACCGCAGTTCCCGCCTGCTGGGACATCTCCGCGCTATCGAGAAGACACTCAAGACGCTTTCCGCTGCACGATGATCAGAGCGCTACGAGACTGGCAATTCAGCTGCATCAACCTGGCGTTGGAGCACTTTACCGTCACGCCAAACTTCTTCTGTCAGGCAACGCCGGGAGCCGGCAAGACGCGTATGGCGGCAGAGCTGGCCAGCAGACTGCTTGAGCAGGGCAAGATCGATCTGGTGTTGTGCTTTGCGCCATCCTGCCAGGTTGTTGAAGGCTTTCGCTCGACCTTTGCGGCGGTGCTCGGCAGGCGTCTGGATGGCCGGATAGGTGCAGTGGGAGCGGCGTTCACCTATCAGGCGATGGAATACCGAGATGAGGGGTTTTGGCAGCTTCTTGATGACTATCGAGTGCTCGTGGTCTTCGATGAAATTCACCACTGTGCTGGTCATGACCCGCTTCTCAGCAATGCCTGGGGGCAACAGATACTGCACCGGATACAAGACCGTGCAGCCTTCACCTTGGCACTCTCCGGTACACCCTGGCGTTCTGACGACAGGGCCATTGCCCTGGCGCGCTACTCGACACCCGAGGGGCAACTGATCTGCGACTACCGTTACGGCCTGAAAGAGGCCATTGCCGACGGCGTGTGCCGTTCCCCTCGTATTGTCCTGCTCGACAACCAGAAGGTGAAACTTACGGAAGAATTTGGTGCGGACAGCTCCGTGAGGCTTTTTCCCAGCATCGCCAAGCTGTTGGGGGAGTCACCTGTCACCTATGAGGAACTGCTGCGCCATGACGAGGTGATCAATCCAATTCTCGACCTTGGCTGCAGCAAGCTCAACGAGCTACGCCAGATCAAGCCTGATGCCGCCGGTTTGGTGGTGGCCACTGATATCGACCACGCCCAGCAAATAGCTGTGACTCTGGAAGCTATGGGTGAAGAGTGCCGCATCGTGACCAACAAAACCCCGGATGTGCAGCAGGTGATCAATGCATTCCGGAGCAGCGCCTCCCGCTGGATTGTCGCCGTGGGAATGATCAGCGAAGGCACCGACATTCCCCGCTTGCAAGTGTGCTGCTATCTCAGCCGTATCCGCACCGAACTGCATTACCGGCAAGTGCTGGGGCGGGTGCTGCGGCGCACAGGTGAATCGGATGACCAAGCATGGCTATTCATGCTGGCGGAACCGGCGCTTCAGGGTTTTGCGGAGCGAATTGCGGATGATCTGCCGGATGACCTTGCGGTTTTGAGTGATGTGCTCATGCCAGGTCTCACTGCAGGCTCCAGGCCTGAGTCAATTGGTGATTTTGACCACATCGAAGGCACCAATGGTGCTGACGTAGGCGACGCGGAATCGGGTATTGGGTCGCAGGCTGTGAACATCATTTCGCTGGTTGGTTTCGCAGCTGAGCCCGCTTATCAGGTCAGCTTTTCCCAGCATTACAGGCAGCAGTTGTTGGCTTGCTTTTGATGATGCTTAGCCAGTCGTGACCGCGGTGGATGGGAGTTTGTCGATCACATTTAGCAGAGATCGGCCAATAGCTGCCTGCTGGAACCGGCCGGAATCGACCCATGGCGGATCTCGCAAGTAGCTAAGAGTGGCTGGTCCGACCCCGTTTCAGGTAATACGCCGACAGCAACGGGGCCGGGTTCCGAGGTTCGTGAAGTAAGCGAACGGGGGTGACCAAGTCTCCCCCCCCCTCCTCACTCATTCGAAGTTCAGACCCAGGCGCTTACGGTTCAAGTCGCTCATGAACAGGTCGTAGATATGGCTGTACTCCTGGGCCTTAGTTTCAATCGCAGTGACCTTGTGGAACCGGATGGAGTCCGCCACGACGGCCAGTTTGGCCGGCGATCCAAATGGGTTTTCCGGTGGCACGGCCATCGGGACAGGATCGGTCGGAGGTACGTAGGAGAGTCGGCTGGCTTCGGGGAAGAGAACCACGTTGGTCCCTGCCTCGCCCGTTTGGACGGAGGGGAACACCAGGCCATCCACGTACTTGCCGAAACGCAGACGCAAGTACTCGAAGACCACCTGCGTCGACAAATAGCTCAACTCGTCATTGCGCGCCTTGGGCCGGGACATCTTCTTGACCAACGAGCCCAGGAACACTTTCCGATGCAGTGACTCGCGGAATCCCTCGTCCAGCAACGTGAGCGCCGGAGGCTCTACGCGGTCCAGCACGGTGAGGTCCAGAAGCTTCAGCTCGCCGATGGGTGTCAGGGCGGCACTGACCACATGGTCGCCGGTGATGGAGCGGATTTCGCTGAGGCACGTCTCTCGCTCCAATGCGCAATACAGGGCGGAGATGCCATTCGGGGTCATCCGTTGACTGCTGGCCAGGTGTTTTGGCGTGGGCCCGAACTGACCGGCGGGATTGCCGATGATTTCCTCTGCCTGCTTTTGGTTCTGGGCATGGCGTGCCCGGTAGAGCAACTCACCATGGGCGATGGTACGCACCACCTCCGGCTTGAGCTGGTTGCCTTCGGTCACCAGCACCGAAAAGACGGAATCGAGGAAATGGTCGGCTCCGGCATTGAAGTAGCGGTGCTTGTAGTGGACATCCTCAACGAACTTCTTCCAGCGGTCCTCGTAGAAGTTCTGCTCCAACGTGCCATCATCGTCGTAAAAGTGCGTTTCGTTCTCCGCGTCGTCCACCCTGAATTCAGGTGGAACGCCATCGCAGAGATCCGAAAAGTAGGGTTCGTTACCGAGTTCAAACCACTCCATGAGGACGATATCGATATCCGAAACGGCGATAAAGTCCGACCCGCAGTGATATAGCAAGCCGAGCTCGTAGTGGGACAGGTCGTCCTTGCGGGCAACATTCTCCGCGACGCGCTCGTAAACGTAGTCGAACAGATGCTTCGACTCCATCACGTGCCCATGTCGGCCGCAGTACTCGCAGTCACCCGCCGTCCCGTATGTGTCGAACAACTTTTTGAGTGGAGCTGGTGTCACGCAATCAACGCAAATCATAGGTGCTTCCTGACCTCGCTTTTCTTGGCCGTCTCAGGATACGGAACGGTCAGCTCTTTCACGCCTGGTCCTTTGCAATTGGTCAGCTGAAACCGTTGCTCAAAGCCATGACCTGCGATCAGGATCCCACAGACCTTGTGCGAACTCCTGGCGTTCGAAACTAGCTATCGCCGGACCGAAGAACTGGCGTAGCTCAGCTAGTAGATCCTCAAATGGTGGCAGCTGGTAGGTTGGCGGATTGCGGCGTAGGAAGCCTTGCCACAGCTCCCCGGCGGTCTCAGCAAAGGCCGGGGTTAGCCCCAAGGGGATGTCCGCCGGGACAGTTGCATCGCGGCGCTGAAAAGTTCCCGTGATCGCCCGGAGCAGGGTCGACAGGTCAACGGAGAAAGTACGGATGATGACCCAGATATCGTGGAAATCTTTTAGCCTGCTGTTGAGCCCACCGAAACGGACCATCGCCTCGAATTTCTCCGCGACCACAGTTTCTGGCGGATACATCAGGATGCGGGCTTGAGGCAGCCCTGGCAGGAGATTGGGAAAGTTTTGCGGTTCAGGTTCAGGGTACACATGATCACCAAAACCGATATCGACCTGCACGGGTATCCTTGCGGAGCCCATTTGCCCCTCCAGGCTGAGACAGATCCCTTGGTACCTGTCCCTCTCTCTCACTGGCTGAATAGACAGAGTGGTGGGATCGAAGGTAATACCGTCCTCTAGGACTTCTACCCGGCAGATTTTCCGAAACAGCTCAAGAATCGCATCCGGGCTGGGGTCTCCGTGGCCAAGTAGATCAATGTCCCTTGTTGGGCGATACACGTGCTCTGGCCAGGTCACGAACAGCATCGCGCCTTTGAGCACGTAGCCCGCTGCCTCGGGTGTTTGGCTAATGCGAAACAGCAACCGCTCCAGGGCATAGCGAGTTTGGATGTGTTGAAAACTGTCGCCTCGCTGTCTGGCCAAATTCAGCAGGCGGGCACTGATTGACGCTGCCGCGTTCTTAACGCCTTTTACGCTCATTGAAGGGCCCTTATGTAGGGAGCAATCCGTCCAGCCACGCGATTGATAGCTGCGTACCGCATCAAATCGCTGGGATTCGTTTTCTGCTTTTGAAGGGCGTCTTTCAGCGCCTCTATCGCTACGTCCTCACCCACATGCCGTCGGTGTTTGAAGCAATCCGCCACGGTTTTGGCTACACAGTAGATTGGTATTTCCACGCCTTCGACGCGGACATGCTCAATGCCGGCGGACATTACCTCGCCAGTGGCGCGCACGATTTCCAGTCGTAGTCCCTGAGGGGTAGGTGTCCTAGCTTTGTGGGGGATTGTCATCCAGACCGCGTGGGGGAGCTGGGTGGTGAGCTGGTGATAGTGGAGAGCGCTGATAAGGCTGATGACTCCATTGGGCACTCGGCGAGCTGCTTCGGCCAGATCGTGAGCGGCGTCCTCACCCAGGCGATTGGGGTCTTGGTAGAGCCCTCGGGCGAGGCGGAAAATATCGCCGGAGTCGCAGAGGCGTTTCAGGTAAACCAGAGGGATGCCGGCAGCGGTGAAATCGCGTGCGCGTACGATGCCCATATCCTGGACAAGGCGTAGGGCTCGCTCCCGATGAGTCATATCGTTTTCAGCCATTTGTTATCTATCGTAGGCAATTTATGTAGTTTGTCACCAAAAGATAACGCTTGAGAGTAAATCCACGACGTCATATATTTCATATGACTATGAATCAGTCTAGCCCCCCCGATGAACTGACACCCAGGCACGTACGGGCAGCACGAGCCCTTCTGGCTTGGTCTCAGCAGGAGCTCGCCAAGAGTGCTGGCGTAGCGACTTCCACCGTGGCCGACTTCGAGCGAGGCCACCGGACACCTATGGCCAACAATGCTCTGGCCATCCGCAATGCCTTGGAAGCCGCAGGCATCAGCTTCCTGCCCCAAGGTGCTGTGATCGGCCCGGCGTTGCCGCCCATTGCGCCAGCCGAGCGTCCAGGTATTCCCATCCGGTGGGTCACTTCGGAAGATCTAGCGGACTGGGCGAACCGCAACGATGCTGTAGAGAGCATGCCGACGCTGCTTTCTCACTTGGTCTATGCGACCGAGGGTGCCGGTGTTTGGCGAAGATTTCCCGCAGACGAAAGCGTGAGGTTTTCTGGGTGGGATGGTTTGACCTCAGGCCAGACCAGCAGCCTTTACGTGCCCAAGGGGGAGGCCGGCTGGGAAATTACAACCCAGCGGAAGGACATCGCGGGGAAGGCCACAAACGATTACAGAAAGCGAACAGAAAACCCTGCGCCACTCGATCCGCACGACGCCACCTATGTGTTTGTCTCCACGCGTCCCTGGCCTTCTAAGCATGAGTGGGTCAGCGAGCGGAAGAAAGAGGGTGTTTGGAAGGACGTCCGTGCTTACGACGCGGACGACTTGGTGCATTGGATCGAGCAAACGCCATCCGTTGGGCTCTGGCTCGCCTCACGTCTGAGCAAACGACCTGTGGGTGTGCGAGAGCTGAATGACGTTTGGGAGGAGTGGTCTCTTGCAACGGTCCAACCGTTGTCCGAAGAGTTGGTTCTGAGTGATAGAGACCAAGACGCCGCCGAGACTCTTCTCTGGCTGAGGCGCAGCCCTTCAATGCTGTCCCTCCAAGCGAACACAGCCGAAGAGGTTGTGGCCTTCTTCCATGCCACTCTGAGGATGCTTCCTGAGGAAGCCTCGATCGCTTACCGAGTCCGCTGCCTGGTCGCCACTACTGCTGACGCAGCGCGAGCTCTTTCAGAGGCACCAGCACCGTTAATTCTGTTGATGATGGAGCCTGACCCGGGCCTGGCAAAGGTTCTCGTGGCACGTGGGCATTACGTGCTCCAGTGCTACGACGAACGGCAGGTGTCCCGCGGCGATCTGCGCACGCTTGAAAGGCCATCGCGTGAAGGGATCGTATTCGCTCTTTCCCAGGCCGGAGTTCCGGAAGCGCGGGCTGATAAGCTCGCCCGTGATTGCGCGCGCAATCTAACCGTGCTCAGGCGTCTCATGCTCGGTGCGCCAGGCCGCCTCCCGCGATGGGCAGATGACGCTCCGTCCCCGGCACTACGAGCTGCGCTTCTCGTGGGCGGTTGGGACGATAGCTTTGAAGCTGACTGCAAGCAAATCTCTGAGCTAGCTGACCTGCCCTATGAAAGGGTCGCTGCAGATTTGGCTCCGCTTGTAGGAAACTTTGACAGCCCGCTCCAGAAGTTGGGATCAACCTGGCGGGTCAAGTCTCCAATGGATGCGTGGATGCTCCTTGCCTCCCATTTCACCGGTTCAGATGTGGCCAGGTTCGAAAGTGTGGCTCTTGCTGTATTGGGAGCCGAGGATCCCCGGTTCGGGCTGACTCCCGAAGAACGTTGGCTGGCTCCCCTGCGAGAAGTTAGGCCGCGCTATTCCGAAATGCTCAGGCAAGGTGTCGGGCAAACGCTCATTCTGCTCGCATTGTGGGGAGACAAGGCGGCTACTGCTCAAGGCGCCAAAGATAGTGCTGATCGTATCGTCCGTACCTTGTTGGAGAATGCTGACCAGGCACGTTGGTGGTCGCTTTCCGGGGATTTCAGACTGCTCGCCGAAGCATCGCCAAGCGAGTTTCTTGATGCGCTTGAAGACAGTCTTAATCGTGATGATCCTCCGCTCGGCGCTCTGTTTGTCATCGAAGATGGGATTGGGGTGGGGACATCGCATTTATGCGACCTCCTCTGGGCCCTTGAATCGCTAGCGTGGTCTCCTGCGCTGCTCACGCGCGTATCTCGCGTCCTTGCAAAGCTCGACGATATCGACAGAACACCTGATCGATACATGAACCGGCCGCGAAACAGTCTGCGAAATATATTCCTGCTTTGGGGGCCGCAGACCTTTGCCCCGCTGGCAAGCAGACTCAAAACTCTCGACGTCCTTAGGGCGCGCGAAAGTGATGCCGCGTGGCGGTTGATGCTGGGGATTCTTCCAAGGGGGAACGACACGTCTATTCCCTCGCCAACTCCGCGCTGGCGGGATTTCACGCCTGATAAAGTCGAGGCTGTGACCTGGAATCTCATAAGCCGCGGCGTTCTGGAGATCACCAAGCGGCTGATATCTGATGCCGGCAGCAGTGCACCGCGTTGGGCTGATCTGATCGAACGCCTGCCCGACCTGGTATCGGGACCAGTCGATGTGATTGCGGAACTCGATGAAGCCGAGAAGTCGATACCGGATGAGGAGGGACGCTCAGTCCTCTGGGCGGCAATTCGCCGTATTCTGCATCATCATCGACAGTTTCCCGAGGCTGAGTGGGCAATGGCGGAAGAATTCCTCAGTCCGCTTGAGGAGATCTACGAGCGCCTCACCCCATCTGACAAGTTCCAAAGGGTTAGTTGGCTCTTTGCGGGCGGCGTTGTAGTCCCCAGGCCGTCGTCTGGCTGGGAGTCTGAGCAGCGCGATATAGATGAGCTCAGGAAGCAAGCAGCGGATAGCCTATTTCGTGATGGTGGGGTGAGCGCAGTCCTGGAGCTCGCTCGGCAGATCGAACTCCCGACCATTCTTGGCAAGGCTTTATATGAGAGTGGGCTGTCTGAGCCTGATCTCCAGTCATTGCTGGAGGCTGCTCTGCTGAGCGGCAGCACTCAAGAGCGGGAACTTGCCCGCGGCCTCATTGCGCCGAGTTTCTATTTCAAAGGGAAGGAATGGGGAGACCTGCTGGTAACCAAGGCTCTCACCGCTGGATGGGACAGTTCGGCAGTCCTCGCAATTTTGCTAGCCCTTCCGACTCAAGCTTGGACGTGGGAGCAGGCGCGACGGGCTGGAACCAAGCTAGAAGAGCGCTACTGGAAGGCCGTTCCGGTGTTCTGGTCGAAGGAACAGAAGCAGGATGTCTGCTATGCCATCGACAAGCTCATTTCAGTAGGCAGAGCCAGGGCCGCAGTAGCGTTTGCGGGTCGCGACACCACGCTCCACCTGCCAACGGCAATGCTTGTTGAGCTGCTGAACCAAGCAGTCATGCAACCTGAGGAAGCTACAGCTGACGCGAATGAAGGGACGATGTTCCAGTACTACGTCGGCGAGATATTCAAGAGTCTCGATGAACGTGATGACCTTGAAGAGAGTGTGCTGGCCCTCCTCGAGTGGAAGTACCTGCAGGTTCTAGAGCATTCGCGGCGGCCTCCTAAGGTGATCTTGGAGTCTCTTTCGACACAACCTCGGATGTTCGTTCACATGCTGACAGCCGCCTTCTCGCCTAGTGAGGAATCACAAGAGGCCGAGGAGCATCAGGATCAGCGATCAACCAGTGTTGCGCGTCAAGCCTATCGGCTGCTCCAGGTTTGGAATCGAGTTCCTGGCACACAGAGCGATGGAACCATTGATAAGAAAGCGCTGAGCGCGTGGATTGATGAAGTGCTTCGCTTGGCCAAAGAAAAACACCGTAAGGACGTCGCGCTGGATCAGATAGGGACAATTCTGTCTGCCTCTCCCGTTGGTGCGGATGGCGTTTGGCCGGCAGAAGCGGTGCGGGATGTCATTGATGATCTCGAGAGTAAGACGCTTCTGAACGGCTTCTATATCGGCAAGCTCAATCGGCGCGGCGCAACGACCAGGCTACTTCGCGATGGTGGTGCACTCGAGCGGACCGAAGTAGAAAAATATCGGAAGTGGGCAAAAGCGCTTGAGTCGGCGAATCCTTACACGGCTAAAGTGCTTGAAATGCTCGCCAGACGTTACGAAGCCGAAGCAAGTCATCATGACGATAGTTCAGAGCGCCAAGACTGGCGGTTCTAGCCTTGAGAAGGCTTGCTCGATTTCAATACCCGTCTGGGTACTACCTTTATCTGGGTGCTAAATGGCTCGTAGCGGCGATTCTCGAAGGCACGCTACCAACCGACGGCGTTGAAAAATAATCTGCAAGATACCGCGAGCCGATGGGCTAGCGTGAAGCGTCCGGTTATCCATAAAAGAATCGGATGTGGTCGCCGATGGCGCTGCGAACTCCCAAGCGCTGTCCCATTGAGTACTTTTTAGCTCTGCGTCGGAAATATAGATAGACAACTCCCGAGGCCCGAGATATGGTCCATTCCGGGTGGCTATAGGCCATTATTTGGCAGTTTCTAGAGGGATTTAGAGTGCACGTTAAATCAATTAGGCTGATCAATTTCAAAAAATTCAAAGATGATCATCTTGAGTTTAACGATGATGTGAATATATTTGTGGGTGATAATAACGCGGGCAAGAGTACGATACTGGAAGCGCTGGAGATCGCACTCAATTATAACTACCGTGGTCGCCCCTTTAACACCGAATTCACGCCTGATCTGTTCAACAAGAGTGCAGTGCAGCAATTCCTGGATTCCGATCGATCATCGGCGCATCTGCCTCGCCTTGTTATAGAGGCATTCATTGATGGCGTTCCAGACTACCGAGGTGCGAACAATAGCCTGCAGATTGATGCTCAAGGCGTAATTGTGCAAGCGTGTTTCGATACCTCACTTCAGGACGTCTATGCCGATTATCTGAAGACAAACCCAAGCATCACCAGCATTCCGATCGAGTTCTATAAATTGGAGTGGCTTGATTTCGGCTGGAATCAGATCAAGGCGGTGGCCAAGAAATTCAGGGCGTTGTACATCGACCCGACACGCATCCACCCAACCATGGGTAAGAACCAGTACATTTCGACCATCCTGAACACTGCGTTGGAAAAGGAAGAGTTGGTCAAGCTGACGCTCAACTACCGCGAGAACCAGCAGGTATTCAATCAATCTGGTGAGGTCAAGGCGGTTAACGACGGACTTGATGCTGAGCACCTCATCACCGACAAGAAGCTCTCCATCGCCGCAAGCACCTTGCCTGCCGGATCAATTCAGACCGGGCTGCAACTTGAGGTGGATGACGTACCGTTTCAGTTCATCGGTAAGGGCGAGCAGAGCAATGTGCAGATCAAGCTCGCGATTCAGAACAAGTCCAAGGACATTGACTTGGTGATGATGGAGGAGCCTGAAAATCACCTCTCTTACAGCAACCTGAACAAACTGGTGCACTACATCGAGAACCAGCGTGGAACCAAACAGCTCTTCCTGACCACCCACAGTTCGTATGTCCTCAACAAGCTAAGCATCAACAAGATCTGTCTCGTTCAGTCGGCGTACCAGCGGCTTCACAAGCTGGATCCCAAGGTCGTCAAGACCCTTAAGCGGTTGCCAGGCTATGACACCTTACGTGTGGCGCTCTCAGGCAAGGTGATCTTGGTGGAGGGACCGTCTGACGAGTTGGTGCTCAAGAAGATTTACTACCGTAAGCATGACCGTCTTCCTGAACAGGACGGCATAGATATCATCGTGGTGCGAGGGGTAGGGTTCGATACTTTTATCGCCGTTGGCAAAGAGATTGGCACCCGGATCAACGTGCTCAGGGATAACGATGGCGCTTACCAGGATAACGTTGTGAAGGCTCGTCAGGAGTACGCAGCATTCCCGAATATCAAGCTTATCTCCTCAGACAACGATCTGGCGTTTTCGCTTGAGCCCGCGATGATTTACGCCAACGCCGCCGATCTGAAGACGCTGGATGCCTTTGCGGAGGAGGTTCTATCCACGCAGACGTACAACCTCTACAAAGTGGTCGGCACTTTGGAGGAGCGACGCGAATTTCTAATCGATTGGTTCCGAAGCGTCAGGGGTAATGGCAAGGGAGCGCGAAAAGTCGATTCGGCGATCAGGCTGTTCGATGGGACATTGGATTTCAAGTATCCGGCCTTTCTAGATGAGGTGTTCGATTTTGGCTAACGAACTCTGGATCGCAGGCGCAGGATCGGGCAAAACGCACAAAATCATCCAGGACGCCATCGAGGTCATCGATGCTGGTGGCCGAGTCTTGGTTGTTACCTACACCACGAGCAATCAGGCTGAGCTGCGCTCTCGTTTCGTCAAGGTGTACGGCAGGAGCAGTGATAATTTTGTCGTAAAGGGCCTGTTTTCTTTCTACCTCGAAGACTTGGTAAGGCCCTACCAAAACGTAGTGTTTCCCGATCGGATCACGACTACAGCATTCACTGAGCACAATCCCCACTTGAGACCTGGTACGACCAAGTGGCTACCCAACCGAGGAGAGAAAATAAAAGGAGTGCTGAACCCTCTGCATTATCTCACCTCTTGCAAGACCAAGGCCTATACAGGTTTCTTGGCAAAGCTGGCGACATTGATCGCGAAACAGACGAAAAACGCTCCTGCCAAGCGGCTGAAAGACATCTATCAGCGAGTGTTCTTCGATGAAGTCCAGGATCTAGTCGGTTGGGATTACGATGTTATTAAGGCATTGAGCAAGGTGATGCCTGACTCAATTTGCTGCGTTGGCGATTTTCGTCAGACCATCTACACCACCACTTTCGGGCACAAGGCACCTCAGACTCCGGTAGAAAAAATCGAATATTTCCAAGGCTTAAAATTCCACCAGCATTCGCTACCGAGGAATCGTAGATGCATTCAGGAGATCTGCGATCTATCCGACACGATACACCCTGGTCTCTATGATAAGACTGTGTCAGAGATGAAGCAGATTCCTGACGAGGTGGTACATCACTACGGCGCATTTGTTGTCAAGCATTCCCAGGTGGGCGAGTACATTGCCGCATTCAAGCCCCAGGTCTTGCGCTGGTCATCGTCGATGGGTAACAACTACTTGCCACCGAACTTGTCCTGTCACACTTTTGGTTCTAGCAAGGGGCTAGGTTTTGATCGGGTTTTGATCTTTTCCCCGGAGAAGCATCTCAAGTATCTGTCTGGCGACGGCAAGGCGTTTGATAAGGATAAAACGGAAGAGTCTCGGAACAAGCTCTATGTGGCCATCACCCGGGCCCGCTATAGCTTGGCTTTCGTGGTCGAGGATGAACTTGTAGTCAAGATGCCTTTGCCGTTATGGGGTGGGGCTGTTCAGGCCGCTGTTGCACCTGTGGCTTAGAGCGCGGCGGCGTGCTTGGCTGCGTAATCGCACTGACTTGACCACCCGATTGCATTCCTCCTGACCAAGCATGTGCATTCGTGCTGACCTCCGCTTGCATGCGGCTTAACCAGTCACATCGTAGTCACGACCGGCTGCAATCGACCCAGGCTGTGTGAAAACGTCGTCCTCGCCTAGAGTTGCTGGAGCAACCTCAGCGGGGGCGGCGTATGAAGCGATTCATCGAAGAGGTGAGCCGGGCACAAGTCAGCTTGCTTCCCGAATGCCTGGATGACTTCGTCGCCGAAGACAACCCGATCCGCGTGGTCGAAGCCTTCGTCGAGCAACTGGATTTGGTGGCCCTGGAGTTCGATGGGGTCACTCCTGCCGTAACTGGGCGACCGTCCTATCACCCCGCCGTGATGTTGAAGGTCTACATCTACGGCTACCTCAACCGCATTCAATCCAGCCGTCGCCTGGAGCGCGAATGCCAGCGCAACCTCGAGCTGATGTGGCTGACTGGGCGACTGGCTCCGGACTTCAAAACCATTGCCGACTTCCGGCGCGACAACGGCAAAGCTATTCGCAATGTCTGCCGGCAGTTCGTCGTGCTGTGTCGCCAACTCGATTTGTTCTCCCAGTCGCTCGTGGCCATCGACGGCAGCAAGTTCAAAGCGGTCAACAACCGTGATCGCAACTTCACCCACGGCAAGCTGCGCGCCCGGATGGAGCAGATTGAAAAAAGCATCGACCGTTATCTGGCAGCGCTGGACACTGCCGACCGAACTCAATCCGATGTCGCCGAAGCCAAAACCAGCCGCCTCCAGGAAAAAATCGAGAAACTCCGCCAGCAGATGCAGGCGCTCAAGGAGATGGAGCAGCAGCTACGTGAAGCACCGGATGGGCAAGTCTCGCTCACCGATCCGGATGCACGCTCCATGGCCACCAGTGGCAAAGGTACTGGCGTAGTCGGCTACAACGTGCAGACGGCGGTCGACACCCGGAACCACCTGATCGTTGCGCACGAAGTCACCAACGTCGGCCATGACCGTGCAGCGCTCGCCACGATGGCCAAGCAGGCTCGCGAAGCCACCGGGTCTGAACGCCTTAGCGTCGTTGCCGATCGAGGCTACTTCAGCGGGGTGGAAATCCTCGCGTGCGAGCAGGCGGGCATTACTCCCTTCGTGCCCAAGCCGATGACCTCCAGCAGCAAGGCTGAAGGGCGTTTTGGTAAACAGGACTTCGTCTACATAGCCGCTGATGATGAGTACCAATGCCCTGCTGGGCAGCGTGCAATCAAGCGCTTCTCGACGGTGGAAGATGGCCTCGAGCTGGATGCTTACTGGAGTTCTGCCTGCCCGAGCTGCCCGATACGCAGCAGCTGCACCACGAGCAGTTATCGCCGACTCAAACGCTGGCGGCACGAGGCGGTACTGGAGGCCATGCAGCAGCGGCTGGATCGCGAACCAGAGATGATGAGCGTGCGCCGCCAGACCGTGGAGCACCCGTTTGGCACGCTCAAATATTGGATGGGCGCGACGCACTTCCTGACCCGAACACTGCCCCGAGTCAGCACGGAAATGAGCCTGCATGTGCTGGCCTACAACTTCAAGCGGCTGATGAGCATCTTTGGCGTTACCGGTGCGATGGAGGCACTGCGGGCCTGAGACCGGCCATTTTCCTACGCCTCTCCACCACAAACTGCCGTAGACCGCCTCAGAAGGCACTGGCAGCGGTTAACAGCCTGTGGTCGATCCTGTCGCACGCTCCTTCGTGGCCCAATCCCGTATGCGGCTCTGGTGTACGCACTTCGCAGTTTTCACACAGCCTGGACCCAAAGCGGACATCATGGCAAGGAAAGGCAGGAAGCCATTCTCTCCATCACCCCCTTCGCTGCGCGGCTGCTTCTGCCGGGAACTGCTTACCGCGATAGCGTATGCTCGCAGGAGGGGTAACGATCATGGAGTGAATTATGAGTAGACGCTACCCGTCGCTCAGAGTCCCGTTAGGTGCAGTGTTTCCCTTCATGCTGATGTCAGTCGATCGCATCTACGCCGTAAGCGTGCTGATCATCTATGGCGTATGCGGGACTGTTCTACCCGATACTGACCAATTCAATTGCGCCTCCAAGGCATCATTTGGCTGTCACGGCCGTTGTCTCGATTGGACTAAGGGCAATTGTCCATGCGAATGGTGATACTGAATTGTTCGGGCCGTGAAAATCTGGGATTATCGGGATGTCACCATTGTGGCTGCTCTGCCTGAACCCCATCTCCTGCTGAGCATCCGAATGATGAATGTTTCCTTTAACTACCCGGCTTCGGCCGGGTTTCTTTTTTTGTTGGCCAGTTTCAGTTGGGACCTGCCAAACTCCGCGGTTATGGTCTTGGCCACGCTTGAGCGCTGCTATCATCTTCGCGGGTAAAGCAGAAGCTATCCCCTAGCAAATGGCTGAGGATGCCAGAGCGGCAGTAGCTCTTAACCTTTCATTGAATGCTTCCGATCCGATGAGGGAGCGAGCAGATGTGCTCGAACCAGATCGGAAGAGGTTCAGTGAAATGCTTTCGGCCCTCATTTCAACCGGACGCCAGTGCTCGAGAATCCTCTGTCGCCTCGTGCAACGGCGGCTGCGGAAGGTTATCGGGCGCAACCTCGAGAATGCGCAGGGCCCCACTCATCACACGACTGAAAACCGGCGCGGCAACCTTGCCGCCGAAGTAGCCGTCGCGGCTGGGCTCGTCGATCATCACTGAGATGGCGATGCGCGGAGCGCTGACCGGGCCGAAGCCGACGAACATCGAGCGGTAGGCGTTTTCCCGGTAGCCGCGCGCACCGGTGGCGGCCTTGCGCGCTGTGCCGCTCTTGCCGGCCACGTGATAGCCGGGCACCCGGGCGCGATGGATGCCGCGGGGCGATTCGACCACCTGTTCGAGCATGGCCGTCACGGTGTGCGCGACCTTTTCCGGAATGACCTGCTCGGGGCGCGGCGCGCGCTCGCGGCGCACCAGCGACAGGGGCATCATGCTCCCGCCATTGGCCAGGGTGGCATAGGCGTGGGCCAGCTGCACGGCGGTTATCGACAGGCCGTAACCGTACGAAAGCGTGGCCGTCTCCGCTGGCCGCCAGCGCGGATAGGCTGGCAGGTTGCCGACGCGCTCGCCGGGGAAGCCCAGACCAGTGTACTGGCCCAGGCCCATCCGTTGCATCACGTCGTGGATGGCTTGGCCGCCGATGTCGAACGCCACCTTGCTCATGCCGACGTTGCTGGAGTTGATGAGGATGCCGGTGAGGTCGAGTATGCGGCCCTCGCTGCGGGTCACGTCGCGAATGGTGTAGTGGCCGATGCGTAGGCTGCCGGGCCACACTTCGACCTGGTCAGACGGCCGCCAGCGGCCGCTTTCTAGGGCGGCGCACATGGAAATGGGCTTGACGGTGGAGCCTGGCTCGAACACGTCGGTCAGCGCGCGGTTGCGGATGGCCGCGGGATCCAGGCCCTGGCGGTTGTTCGGGTTGAAGCTGGGCTGGTTGGCCATCGCCAGCAACTCACCGGTACGCACGTCGATCATCACCAGGCTGCCGGCCTTGGCGCCGAACTGGTCCAGCGCCCGCCTCAGTTCGCGGTTGGCGAGGTATTGCAGGCGCAGGTCCAGCGACAACGCCAGGTCCTTGCCGGGCTTGGCGTTGCGCACGACCTGCAGGTTCTTCACCACGCGCCCGTACAGGTCCTTGAGCACCAGGCGTCGGCCGGGCACCCCGGACAGCCAACTGTCGAAGGCATATTCCACGCCCTCCTGGCCGTGGCCGTCGATATCGGTGAAGCCGACCACCTGGGACGTCGTATCGCTGGCCGGGTAGAAGCGCCGATACTCTTCCCGCGCATAGACGCCCGGCACCTTGCGCGCCAGGATGGCCTGCCCGACCACCGGCGGCAGGCCCCGCTCCAGGTAGAAGAACTCGCGTTCGCGGTTGGCCTGCAGGCGCGCCGCGAAGGCCGCAGGCGTTTGGCCCAGGGCATTGGCGAGTTCCGCCCAGCGCTCGGGGGCCGCGGCCAGTTCCCTGCCGTTGGCCCAGAGGGTGAGCATCGGCGTGCTCACCGCCAGGGGCTCTCCCCGGCGGTCGGTGATCTCGCCGCGATGGGCGGGAATCTTCAGATAACGCAGGCTACGCGCATCGCCATGGGCCTGCAGGAACTCGCGCTGATGCAATTGCAGTTCGAGCAGGCGCCAGCAGAGCACGGCCGAAAGAAGGCCGAAGAGCAGGATGACCAGGCGCAGGCGCCAGGGGTGGCTGAGGCTGGGTGGAATGTTCATTGGGCGACGCTGTCCGGGCGTTTCACTGGGCTATCTGTCGACCTGGGGCGCTGAAAGGGGGGCAATGTACCACGTCATCCGGACTGGCCTGCTTCGGGCGTTCGGCCCGCGAGGCTGACGGTCGTTGTGCGTTGGGCCGAGCGCCGGCTGGCAGGCCCTGTCGTTACGCATGGTCACTCGGGCGGTCGACCGAAATCCTGAACCCCACTGTCAGCAGTCGGTCGACCGGATTGTCGCCGTATCCAGCACGATTAAACGGGCGGTTCAGCGATTACTTCAAACACGACAACGAAGCGAGGATCAACCCATGCAGACTCAAGACTACGAGGCCTGTTTGCAGGCGTGCACAGACTGCGCCGTCGCTTGTGAGCGATGTGCCAGTGCATGCCTGGGCGAAGAAAATGTGCGGTCGATGGCTCGATGCATCGAGCTGGATCGCGATTGTGCCGATACTTGCCGTCTCGCCGCATTGCTCATGGCCAGAAACAGCTCGTTGGCCAAAGACGCCTGCCGGCTCTGTGCATGGATTTGCAGGGCATGTGGCGAGGAGTGCGGCAAGCACGAGCATGAGCATTGCCACCAGTGCGCGGCGGCTTGCCGACTCTGCGCCGAGGCTTGCGAGCGGATGGCAGCCTGAAGTCTCGGGCACCGGTAGCGGATGCAATCGGTGCCTTGGGGGCTCAGGCCTCGCGTTCGGTGCTGGCGATGAGTCGCGAGTCGGCCAGGGCGGCTGTGCGATGCACCGTTGCCGCACGATATTCGCTATCGGCCAGCATGCTCAGGAACGCTTCCCTCGAGGGGTAGCGCACCAGCAGAATTTCGTCCCATCGCTCGTCATCCGGAGCGATGAGCGCCACATGGGCGTCTGCCAGCAGCCGAACCGATCCGCCGACTGCGGCGACTTTCGCCCCGGCGACGCGGGCATAGCGGGCATAGGCCTCGCGGCCGGTGCAGGGGGACGCTCCCTCATCTGGCGGATAGTCGGCTTCGGTCCGGTAACGCAGCAGATTGAGCATCAGTATCGGCTTGCCGGCCGGCATTTCCTCGGTGAACCGGGCAAGTTGTTCGCGGCTTGGATTCAGGCTGGGCATGGCGTCGCTCCGGAAGGGGTGGGGATGACGTTGCTGCCGAGCGAGTTGGGTGGTCAAGGCCTATGCATGTGCTGAATGGCGCCGGATGACCCTGAGGCGGATCCTGGATCGGATCGTTCACTTCGCGCGCGCAGGCTCCCTTCCCTTGTCCTGACGCATGACGAAAGCCCCCCAGGCCAGCCCCAGCGCCGCGGCGAAGGTGGAGCCGATCAGTACGCCGAGCTTCGCGGGGCCGAGCAGACTGGGCTCGGAGAAGCCGAGCATGGCGATGAAGATCGACATGGTGAAGCCGATACCCGCGAGCAGCCCGATCAGGATGACGCCTCGCCAGGTGACCCCGCTCGGCAACGCACACCAGCCCAGGCGCACCATCAACCAGGTGATGCTGATGATGCCGAGTGGTTTCCCGACGATGAGCGCGGTGGCCACGCCCAGCAGGACCCAATGCGGCGCCTCGGCAGCCAGGTCGATGCCCTGGAGGCTGACCCCGGCGTTGGCAAGGGCGAACAGGGGCATGATGCCGTAGGCGACCCAGGGATGCAGGGCCTGCTGAACGCGTACCACGGGCGGGACCAGTTCGCGTTGTGCATGGCGCAGGCTCTTCAGGGGTGGCATCAGGTCGCTTGCGTCCTGTTCCGGCGATTGAGCCCGGCCGATCAGTTCGCCGGTAATGCGCGAAACACGCTCCAGGGGGCGCTCCCGCATCGGCATGCTGTACACCGGTGTCATCAGGCCGAGCACCACGCCAGCCAGGCTGGGATGCGCCCCGGTCATGAGCAGGCCGGCCCAGGTCACCGCACCCGGAAGCACATAGGCGTAGGCGGTTCCGACGCCGATCTTCTGCAGGCCGAGCACGAGCAGGATGCCCACTGCCGCGATGGCGAAGCCACTGTAGTCGAGGCCTCCAGAGTAGAAGACGGCGATGATCAGGACCGCGATGATGTCGTCGATGACGGCCAGCGCCAGCAGGAACACCCTGACGTTGGCGGGGATGGATTTGCCCAGCAACGCCAGCACGCCCACCGCGAAGGCGATGTCGGTGGCCGTCGGTATGGCCCAGCCCGAGTGCGCGGCGGGGGTGTGGTTTATCGCCAGGTAGATCGCTGCCGGCGCCAGGACACCACCAACAGCCGCTATCATGGGTAATGCCGCCTGGCGCAGGTTGGCCAGGGCACCCTCATGGATTTCCCGGCGGATTTCCATGCCGACGACCAGGAAGAACACGGTCATCAACCCATCGTTTATCCAGAAGTGGAGCGAACGCGAGAACGTGAAGGAGCCGATTCCGATGGACAGCGGAGCGTGCCATAGGGCGTCGTAGCTATGAGCGGCCGGGGAGTTCGCCCACAGCAGGGCGATGACGGCTGCGACCAGCAGGACGGCGCCACTGACGGCTTCGATATGCAGGAAACGTTCAAGGTTGGCGAAGGCGCGTTCGGCCATTCGCTGGGCACGGGGCAGGGGATTCTGTTGCATGCGCACAAGCTCTCCGCGCGGCGGCCCGACCTGCGCATTGACCTGTCTCGCCACCCTTGCAGCAGACACCCGGAGCGCAAGTCTACAGGACCCTTTCGCGGTCAGTGAAGTTCCAGCGCTTCACGTTCGCACCGTTGCGTAAGCGTCATCACGCTGGCTGGAGTGTCAGGATTCGCTCGGCGAAAAAAGCGCCCATTTCCCATTTGCGGTAGGGATAGCAGGCCATGCTTGTTACCCTTGATAGGTTTTCCGCTGTGCTTCGGCACACAGATTCAAAGGAGAAAACCCGCAATGAATGCCCCATCCAAGCCAAGGAGTACCCTGAATCCACCGGTGTTCTACAGCAGTGCAGTGCTTATCCTGGTACTGGTGCTCTATGCCTCCGTTTTCCAGGAGCAGGCACAAGCGTTGTTCAACGACGTGCAGCAATGGATCATCACCAATGCCAGTTGGTTCTACATCCTCGCGGTGGCGCTGATCCTGATCAGCGTCGTGTTCCTGGCGGTCAGTCGCTATGGCGATATCAAGCTCGGCCCCGACCACAGCGAGCCGGAGTACCGAAGCAGCAGTTGGTTCGCCATGCTGTTTTCCGCCGGCATGGGCATCGGCCTGATGTTCTTCGGCGTCGCCGAGCCGGTCATGCATTTCACCACGCCGCCGGTGGGTGAACCGGGCACGGTAGCCGCCGCGCGCGAAGCGATGAAGATCACCTTCTTCCACTGGGGCCTGCATGCCTGGGCGATCTATGCGATGGTCGGGCTGATCCTGGCTTACTTCAGCTTCCGCAAGGGCTTGCCGCTCACGCTGCGCTCGGCGCTCTATCCGCTGATCGGCGAGCGCATCCATGGGCCCATCGGCCATGCCGTGGACATTTTCGCCATCCTCGGCACCGTGTTCGGCGTCGCCACTTCGCTGGGCTATGGCGTGTTGCAGATCAACAGTGGTTTCCACCATCTGTTCGGTTTGCCGGTGAACCCCTCCGTGCAGATCGTCCTGATCGCCATTACCTGCGGCCTGGCCACGCTTTCGGTGGCCAGCGGCCTGGATAAGGGAATCCGCATTCTTTCGGAGCTCAACCTGGGATTGGCGGCGGTGCTGCTGCTCTTCGTGCTGTTGCTGGGCCCCACGGTCTTCCTGCTGCAGACCTACGTACAGAATACCGGCGCCTACCTGTCCGATATCGTCTACAAGACGTTCAATCTCTACGCCTACCAGCCCACGGACTGGATCGGTGGTTGGACTCTGCTGTACTGGGGCTGGTGGTTGTCCTGGTCGCCTTTCGTGGGTCTGTTCATCGCGCGCATCTCGCGTGGCCGGACGATTCGCGAGTTCGTCTGCGGCGTGCTGTTCGTGCCGGCCGGTTTCACCCTGTTGTGGATGACGGTGTTCGGTGACTCGGCGATCCACATGATCCTCACCGATGGCGTGCAGGACCTGGCGGCGATAGTCGACCAGGACAGCTCACTGGCGCTGTTCGCCTTCCTCGAGCATTTCCCGCTGTCGAGCGTGGTGTCCATGGTCGCGGTACTGATGGTGGTGGTGTTCTTCGTCACTTCCGCCGATTCCGGTGCCCTGGTGGTGGACATGCTGGCCTCGTCCGGGCATGACCACTCGCCGCTGTGGCAGCGCATCTTCTGGTCGGTGAGCATCGGCGTGGTGGCGATTGCGCTGCTGCTGGCCAACGGACTGAAGGCACTGCAGACCGCGACCATCGCCAGTGCGTTGCCGTTCTCCATCATCCTCCTGGCGTCGATCTGGGGATTGTTCCGTGCGTTGCACCTGGACGCAACCCGCCGGGGCCTGCGCAACCAGGCACTGCCGTCGCCGCGCCAGGCGCCCCATGCCCATGGCGGCTGGCAGCGGCGTCTGCGCAACATCGCCATGTTGCCGCGGCGTGCCCACGTGACGCGCTTCATCGCCGAGGTGGCGAGGCCGGCGTGCGAGGAGGTCGCCGTCGAATTGCGCAAGCAGGGCTACGAGGTAACGGTGAGCGAACGCGAAGACGGCCGTGTGAGCCTGGAGCTGGACCACGCCGGCGAAGGCCGCTTCCTCTACGAAGTGCGACCGCGCGCGTTCACCACACCCAGTTTCGTCATGCGTGACACCGAGGAGAGCAGCGATGCGCGCAAATACTTCCGTGCCGAGGTGCATCTGCGCGAGGGTGGCCAGGACTACGACATCATGGGCTGGAGCCGCGATGACGTGATCAGCGACATTCTCGATCAGTACGAAAGGCACCTGCACTACCTGCACGTCGTCGGCTGAATGAGCGCGATTCGCTGCGCTAGAGGGGCCGGGACGTTTCGGTGGTCGTCTCGCAGGCCCAGAAATCCATGGCCGGGGTCTTCGTCGTCGGTGGCCCCAGCCAGTGCGCCAGCGCCTGGCATCCGTGTTCGGTGCACAGTTGGTAGTCGCCGGCCTCGGGCGTGCGCCCGGCGTGCAGCGGTTGCAACGGTGGAAGGTGGCGCCGGTAGTGCCAGGCGCCGTCGCGCAGGACCGCACCGTCCGGAATTTCCATGCCGGCGCCGTTGCCGCGCACTCTCGCCTCGCCCAGCAGCAGGCCGGCAGAGGTTACCTGGTAGTCCTCCTCCCAGCGGATCTTCTCGATGCTGTGCTGCCAGGCCAGGGTAAAGTGCTGCAGCGGCAGGCTGGCCCAGACCACCCCGGCCAGCCCCAGGCACAGGCCGGTCATGCCGGCTGCCCGGCCGCGCCGCGATGGCGCCACAGGTGCCAGCCGAGCACCGCCGCGCCCAGGGCGAAGCCGGCTTCGTCGCTGATCGGCAGGGCGAGGATCAGCAACAGGCCGGCGGCGAACGCCAGGCCGCGCTCCCACCATGGCATGGGTGCACTGAGGTGGCCGATGGAGGCCATGCCCCAGAGCACCACCGCGAAGATCGCCTTGACCAGCATGTAGAGCGTGGCCGCCCAACTGTCGCCCTGCATCATCAGCGCCGGGTCGTAGACCGCCATGAAGGGCACGACGAAGCCGGCCAGGGCGATGCGCACCGCCCAGAAGCTGATCTTCAGCCCCTTCTCCTGGGCGATGGGGGCGGCGGCGAAGCAGGCCAGGGCCACCGGCGGGGTGAGGTCGGCGAGGATGCCGAAATAGAACACGAACATGTGCGAGACGATCAGCGGCACGCCCAGCTCCAGCAGGGCCGGGGCCGCGATGGAACTGGTGATGATGTAGTTGGGGATGGTCGGGATGCCCATGCCCAGCACCAGGCAGGTGAGCATGGTCAGCACCAGTGAGAGAAACAGGTTGTCGCGACCCAGGTCGAGGATGTAGCCGGCGAAGGTGGTGGCTACCCCGGTCAGCGAGATGACGCCGATGATCACCCCGACCAGGGTGCAGGCGATGCCCACCGGCACAGCATGGCGGGCGCCTTCGGCCAGGGCCATGACGCAGGCCCGCAGGGTGGCGTGGCCGCCGCGGATGAAGAAGCAGGCCAGTGCCAGGGCGGCGATGACCAGGAAGACGATGCCGATACCCAGGCGGAAGAACCCCGAGCAGAGCACCCCTAGCGCCACCCAGAAGGCGATGCGCAGCCAGGTGTTGCCGGCGCGCAGGATGATCGCCGAGCCGAGGATGACAATGGCAGTCAGCGCTAGGCCGACCATGCCCGAGTACAGCGGGGTACGCCCGGAAAACAGCAGGGCGATCAGCACCAGCAGCGGGATCAGCAGGAACCAGCGCTGGCGCAGCGCGCCCCAGGCGCTTGGGCATTGCTCCGGCGGCAGGCCGTGCAAATGGCTGCGCCGGGCCTCCAGGTGGACCATCCAGTACACCGAGCCGAAATACAGCAGGGCCGGGATCAGCGCCGCCTTGGCCACCTCTGCGTAGGGCACGTTGATGGTCTCGGCCATGATGAAGGCCACCGCCCCCATCACCGGGGGCATGATCTGGCTGCCCATGCTGGAGGTGGCTTCGACGCCGCCAGCGAAGGCCGGCGAGTAACCGAAGCGTTTCATCAGCGGAATGGTGAACTGCCCGGTGGTGACCACATTAGCCACCCCGGAGCCGGTGATGGTACCCATCAGCGCCGAGGAGAACACCGAGACCTTGGCCGGTCCGCCGCTGCGGTGGCCGAACAGGCCCATGGCGAAGTCGGTGAACAGGCGGATCATCCCGGCCTGTTCGAGGAAGGCGCCGAATAGGATGAACAGATAGATGTAGGTGGCCGACACATAGGTGGGCGTGCCGTACAGGCCCTCCGTGCCGAAGGATAGCTGGTTGACGATTTGGTCGAAGCCATAGCCGCGGTGCGCCAGGTCGCCCGGCAGGTACTGGCCGAGCAGACCGTAGACGAGGAACAGGGCGCAGATGATCGGCAGGGCGATGCCCATGACGCGCCGGGCGGCCTCGAACACCAGCACGATCAGTACCAGGCCGATGAGCATGTCGCCGTGGGTCAGTTCGCCGGAGCGCTGGATCAGGTCGGCCTCGAAGAACCACTGGTAGGCCGCCGTGGCCATGCCCCCCAGGCCCAGCAGCCAGGCTAGCGGCTGCCAGGGACGGCCATGGCCGCGCGCCGGGTAGCACAGGTAGACCACCAGCAGCAGGAAGCCCACGTGCACCGCGCGCAGGACCTGGGTGGAGATCAGCGGAAAGGCCGCGGTGGCGACCTGGAAGATCGAAAAGGCCAGGGCGACGGCGAACAGGCTGGTGGGCCAGCGCTCGGTGTCGGCATGCAGGCCGTGGGCGGTATCGCTCATTCGGGGTCTCCTGCGGTGGCCGGCCCCGGCGTGGGGCCGGCCCATGGCTCAGGGAAGCAGACCTTTTTCCTTGTAGAAGCGCTCGGCGCCGGGGTGCAGCGGAATCGGCAGGTTCTTCGCCGCCTTGTCCAGGCTGATGTCCTTGGCCGCCGCATGGGCGGTGACCAGGCGCGGCAGGTTATCGAACAACTGCTTGGTCATCTGGTAGGCCAACTCGTCACTCACCCCTTCATGGGTTACCAGGATATTGACGATGGCGGCGGTGGGCACGTCGGCGTCCTGGCCGTCGTAGGTCTTGGCCGGGATGGTCGCCGGCAGGTAGGCGTTGTTGCCGATCTTCGCCACCACCTCGGCGGGGATCGCCACGAAGCTCACCGGCATGGTCGAGGCCAGGTCGCGGATCGATGCCTGGCCCAGGCCCGAGGACTGCAGGGTGGCGTCGAGCTGGCGGTTCTTGATCAGCTCCACCGACTCGGCGAAGGGCAGGTACTCGACCTTGCCCATGTCCTCGTAGCTCAGCCCGGCGGCCTTGAAGATCGCACGGGCGTTCAGCTCGGTGCCGGACTTGGGCGCGCCGACGGAGATACGCTTGCCCTTGAGGTCGGCCAGGGAGGTGATCCCCGACTCCTTGCTGGCGACGATTTGGATGTAGTTGGGGTAGGTGCCGGCGATGGCCCGCAGCTTCTTCAGCGGCGTCTTGAAGCCGGCGTCGGCCTCGCCCTTCCAGGCGTCGGCCACCGAGTCGCCAAGGGCGAAGGCCAGTTCGCCGCGGCCGGCCTGCAGCAGGTTGAGGTTCTCCACCGAGGCCTTGGTGGCCTGCACCGAGGTCTTGCTGCCCTCGATGCCGTGGCTGTAGATCTGCGACAGGCCGACGCCCACGGGGTAGTACACACCGCTGGTGCCGCCGGTGAGGATGTTGATGAAGACAGGGGCGGCCTGGGCGGTGGCGCAGACGGCGAGGAAGGCGGCGCCGGCCAGCGCCAGGCGGGTGCGTCGGATCATGGCTGGGTCTCCAGGTTCTTGTTCTTGTGCCTGAATGACTAACCGTAGAACGCTTGCGCCCGGCTTGCCCAGGTTTTTAGCCGAAAGTCTAAGAGCGCGCGACTGCTTTTAGCTCAGGGTTTATTTGGTGCCAGCTTGTCGAGGATCTGCCGCGCCAGGGCGTGGTACAGCGAGACCGGTGCGATCCAGCCGGAGACGGTGGCGGCCATGACCGTGGCCGCCAGCATGGGGATGAGCAGGTCGGGGCTGTGGGAGAGTTCCAGGACGATCACCGAGGCGGTCAGCGGCGAGCGCGTCACCCCGGCGAGGTAGGCGCCCATGCCCAGCAGCGCGCAGGTCTGCGGGTTGACGTCGGGCAACTGGGCCAGCAGCGGGGCGAAGGCCGCGCCTATGCTCAGCGAGGGCGAGAACAGGCCGCCGGGGATGCCGGCGAGGTAGGACACCACGTTGGCCAGGAACTTCCACAGCAGGAAGCTCTGCTCGGTCATCGGCTGGCCCTCCAGCAGGGCGCGGGTCTCCTCGTAGCCGGTGCCGAACACGTGGTTGCCCGAGGCCAGCCCCAGCAGCGCCAGCAGCAGCCCGCAGGCACCGGCGAAGCGCACCGGGAAGCGCTCGCGCAGGCGGCACATGCGGCCCAGCCAGCCGACCCGGGTGGGCAGCACCAGCTTGACGTAGAGCCCGCCCAGCAGGCCGCCGAGCAGCGCGCAGGCCGGCACCTCGCTCCAGCCCCAGCCCGCCGGCAGGCTGCCGCCGATCTCGCCGAAGTAGGAGTAGTGGCCCATCAGCCCGAGGGTGACGGCGCCGCCGATCAGCACCGCGGTCAGCACCAGGCCGCTGAAGCGCTGTTCGAAGGTGCGGCTGAGCTCCTCGATGGCGAACACGATGCCGGCCAGCGGCGTGTTGAAGGCCGCGGCGATGCCGGCCGCGCCGCCGGCGAGGATCAGCCCGGCGATGGTGCGCCGGCCGTGCAGCCCCAGGCGCCGGCCGAAGGCGTAGATGACCGCGGCGCCGACGTGCACCGTGGGCCCTTCGCGGCCCACCGAGCCGCCCACCAGCAGCGCGCCCAGGGTGAAGACCATGCGCACGGCGGCCACCGGCAGCGCCAGCACCTGGGCGCGGAAGCGCCGCGAAGGCGACTCCAGCGCGGCGATCACCTGGGGAATGCCGCTGCCCTTGGCCTCGACGAACCAGCGCTGGGTGACCCAGGCCAGCAGGGCGAAACCCGCGGGGGTGACCAGCAGCGGCAGCCAGGGGGCGACGCCGAGCGTGCGCTTGAACAGGGCGAAGGACTGGTCCGCCAGCCAGGCGAAGGCCAGCGCCAACAGGCCTACCAGCAGAGCCCCGACCCAGAACGCCAGATGTTGTCGCCAGAGCCGCCAGCGAGAATGGTAGAAGCGCCGTGCACGGCTGACGTTTGGCTCGCTGTCGGCAAGGTTGCGGGAGGGCAGATTTGCTGACTGGTCGGACATGATTGATTTCTGGTTGCGGAAGGGAGGATGAATCTTTGTCTTCGCCAGATTTGGGCGTCGGTGGCCAGTGGAATAGTACCAGTGGTCTGTCCCGGAACTGGTGGACAAGTAGTTAAGAGCTACTGCTCGCATTTCGCCGCTCAAACTCCATCGGACTGAGATAACCCAACGTCGAGTGGCGACGGCGGTGATTGTAAAAGCGGATGTAGTCGAACAGGTCGGTTTTCGCCTCCTGGTAGCTGGCGTAGCGAGTCAGGTACACCCGCTCGGCCTTCAGCGAACGGAAGAAGCTCTCCATCGCGGCGTTGTCCCAGCAGTCCCCGGACGTGAATGGCTGGGCACGATTCGATGTCGCCGAAGCAAGGCCTGGTAGTCGTACGCGCAGTATTGGCTGCCACGATCCGAGTGCAGCAGCACTTCTTCTTTCGGCTGTCGGCGTGCAACGGCCATCTCCAGAGCAGCATGCACCAGGGCCTGCTGCATGCGGTGGTGCATCGCCCAACCGACGACAGCGCGTGAATAGAGATCGAGCACGACGGCCAGATACAGCCAGCCTTGGGCCGTCCGCACGTAGGTCATGTCCGAGACCCAGTGCCGATTGGCGCGATCCGAGGCGAACTGGCGATCCAGGTGGTTCGGGGCAATCGGCAGAGCATGACGACTGCTGGAAACCAGCCGCCAACGCTTGCGCGAACGAACACGCAGGCCGGCTTCGCGCATCAGTCGAGCGACTCGGTGTCGACCACACGCATGCCCCATGGCCGCCAACTCGGCCTTGATTCGGCGATGGCCATAGATCCCATTCACCTCGTGGTGGATGGTGCGGATCTCCTGGCTCAGACGCCGATTCGCCATCTCTCTCGCCGAGGGAGGCCGCTGCTGCCAGGCATAGAAACCGCTGCGGGATACCTGCAGCAGCCGGCACATCGGCGCTACGGGATAGCGACCGGCCAACGCCTCGATGGCGCGGAACTTCACTTCGTGGGCTGCGAGAAGATGGCGAGCGCCTTTTTTAAAACATCGCGCTCCATGGTGACTTGAGCCAGTTGCTGGCGTAGGCGACGCAGCTCCGCGCTCTCGCCCCGCTGCTTGCCATTGCCCGGAAAGGCATCCTCACCTTGCTGCTCGTACTGGCGCTTCCAATTGCCCAGCAGGCTTTCAGCGATGCCGAGCGTCTCGGCTACATGACGAAGCGGCGTACCGGCAAGCACCTGGTCTACCGCCTCGCGTTTGAAAGATTCGGGAAAACGTCGTCTGGTCTGGGTCATGAACACTCCTTGCGGTGGACATTATCCACCTTAAGTCAGTGTCCACTCAGCCCGGGACAGACCAGAGTGAGGCTTTGACTAGCTAATGAATGCTGAAAGCCGCTATAACCTCTGCTACTGAATAAGAGGATGGAAGCATGCCTCGGCATAATTTCAACGACCTGCAAGCCTTCGTGACGGTGGCGCGCGAGGGCAGTTTTACCCGTGCAGCAGCACACCTGGGCATAACCCAATCTGCGGTGAGTCAGGTTGTGTCGGCGTTGGAGGCACGGCTGCAGATTCGTCTGCTCACACGCACCACCCGCAGTGTTTCGCTGACGGCGGCGGGTGAACGGCTCATGGACGCCATCGGCCACCGTTTCGATGAGATCGAAGCCGAGCTGGATGCCCTGACCGAGCTGCGCGACAAGCCGGCGGGCAAGGTTCGTATCACTTGTGGCGACAACATCATCAAGACGACCTTGCTGCCCAAGCTGATCCCCCTTCTGGCGGCCTATCCAGACATCAAGCTCGAATTCGATATCAACTACGGTTTCCGAGATATCGTGGCTGACCGTTTCGATGCCGGCGTGAGCTTCAGCGGTACGGTGGCGCAAGACATGATTGCCATGCCCATCGGCGGCGATCTGCGCATGGCCGTGGTGGCCGCCCCCAGCTATTTCGCCGAGCACCCCATACCCAGGCATCCTAACGACCTGGCTGCGCATAGGTGCATCGATATCCGCTTTCCCACCTACGGCGGAGTGGATGCCTGGGAGTTCGAGCGCAAAGGCAAGAAACTGAGGGTGAGGGTCGACGGGCAGCTGGTGTTCAACACCACCACCCACATCGCCGACGCCGCCGTCGCAGGCTTGGGCATCGCCTACCTGCCCGAAGATGAGTTTGACCCTCACCTTGAAGAGGGCCGGTTGATTCGAGTGCTGGAAGACTGGTGCGAGCCGTTTTCCGGCTATAACCTCTACTACCCCAGCCGCAGGCAACCTTCGCCGGCCTTCGCTCTTGTACTCGAGGCGTTGCGATTGACGTAGTAGGTGGAAAACAACGGGATCGGTTCCATTTTGCCCGTTATGTCCGCTTCTGGCCGACACCCGCCTGTCTCGGTCGGCGGCTCCCGACCCGAAGCAATGGGATGGACTCCCCCTCGCCTCGGCATCTGAGTGCCAGACTGAAGGTGCGAACCACAGTTAACAGCTAGAAGGAGTCCACACATGAAGCTTATGCGCATTGGGGTCGACTTGGCCAAGAACGTGTTTCAGATCCATGGCGTTGACTGTCACGAGAAGCCGATTTGGCGGCAGCGCTTACAACGCGATCTATGGCTACAAGCCTTGCTTGAGCAGGCTGAGCCAGGCTGTGTAATTGGCATGGAAAGTTGTGGCGGTGCTCACCATTGGGCGCGGCAACTTGAGGCTCGTGGATTCCAGGTCAAGTTAATTGCTCCCCAATTCGTCAAACCCTACGTCAAAAGCAACAAGAATGACGCCAATGATGCTGAAGCAATCTGTGAGGCGATGAGCCGGCCCAGCATGCGTTTCGTAGCTATCAAAACAGTCGAGCAGCAGGACATTCAGGCGACCCATCGAATTCGTGCCGGGTTAATTGAGCAGCGTACGGCAAAAGCCAATCAGATCCGTGGGCTGGTCGCTGAGTACGGTCTAATTGCACCGAAAGAATTGCTCTCGCTGCGTCGAGCAATACCGTGCTGGCTGGAAGATGCAGACAACGGTTTAACGCCGCGTTTCCGACATCTACTGGATGGCTTGTGGGGCGATCTGCGCGCACTGGATGCACGGGTGAGAGAGCTTGATAGCGAGATATCCGTGATCGCGGCAAATGAGCCTGACGCTCTATGTCTACAGCAACTGCGTGGTGTCGGCCCGATGATCGCCACTGCACTCGTCGCTGCCATCGGTGACGCTCGTCAGTTTGCCAATGGCCGGCAGTTTGCTGCTTCGCTGGGATTAACGCCCAAACAACATAGCTCCGGCGGCAAAGATCGATTGCTCGGCATTAGTAAACGCGGCGATGCCTACTTACGGACACTGATGGTTCATGGCGCTCGATCAGCGTTACGTACAGCCAATTCCAAAGACGACCGACTTAGCCAGTGGATCGTCCGCCTGGCTGAGCGATCACATGCCAACGTGGCAGCAATCGCGCTGGCCAACAAAACCGCGCGCATGGCTTGGGCGATACTGCGTAACGGCACCGATTACCAACCGGATCGGGCTGCTGCCTGA

Protein sequences of DBSCAN-SWA_1

>NC_020829|935654:978058|966004_967363_-|WP_015475642.1|DBSCAN-SWA
MQQNPLPRAQRMAERAFANLERFLHIEAVSGAVLLVAAVIALLWANSPAAHSYDALWHAPLSIGIGSFTFSRSLHFWINDGLMTVFFLVVGMEIRREIHEGALANLRQAALPMIAAVGGVLAPAAIYLAINHTPAAHSGWAIPTATDIAFAVGVLALLGKSIPANVRVFLLALAVIDDIIAVLIIAVFYSGGLDYSGFAIAAVGILLVLGLQKIGVGTAYAYVLPGAVTWAGLLMTGAHPSLAGVVLGLMTPVYSMPMRERPLERVSRITGELIGRAQSPEQDASDLMPPLKSLRHAQRELVPPVVRVQQALHPWVAYGIMPLFALANAGVSLQGIDLAAEAPHWVLLGVATALIVGKPLGIISITWLMVRLGWCALPSGVTWRGVILIGLLAGIGFTMSIFIAMLGFSEPSLLGPAKLGVLIGSTFAAALGLAWGAFVMRQDKGREPARAK
>NC_020829|935654:978058|977026_978058_+|WP_015475652.1|transposase|DBSCAN-SWA
MKLMRIGVDLAKNVFQIHGVDCHEKPIWRQRLQRDLWLQALLEQAEPGCVIGMESCGGAHHWARQLEARGFQVKLIAPQFVKPYVKSNKNDANDAEAICEAMSRPSMRFVAIKTVEQQDIQATHRIRAGLIEQRTAKANQIRGLVAEYGLIAPKELLSLRRAIPCWLEDADNGLTPRFRHLLDGLWGDLRALDARVRELDSEISVIAANEPDALCLQQLRGVGPMIATALVAAIGDARQFANGRQFAASLGLTPKQHSSGGKDRLLGISKRGDAYLRTLMVHGARSALRTANSKDDRLSQWIVRLAERSHANVAAIALANKTARMAWAILRNGTDYQPDRAAA
>NC_020829|935654:978058|948069_948660_+|WP_015475630.1|DBSCAN-SWA
MKTASFTFDRRLYELLQEEARARFTTRELRDAYAKRLDGVNFRISDVRRYVYEQIRRMLRMGWVVHDEERRSRGQVYRLQPKPVHLQLELIDDGFEKSFKTASEPTQESSVQDHAAVPLEPSSDAEQHLEALHNEIRLDFLSSMGEAERYKLLLGDMPHLRDKVEAEYLEARDRSSRLLGHLRAIEKTLKTLSAAR
>NC_020829|935654:978058|970051_972079_-|WP_015475645.1|DBSCAN-SWA
MSDTAHGLHADTERWPTSLFAVALAFSIFQVATAAFPLISTQVLRAVHVGFLLLVVYLCYPARGHGRPWQPLAWLLGLGGMATAAYQWFFEADLIQRSGELTHGDMLIGLVLIVLVFEAARRVMGIALPIICALFLVYGLLGQYLPGDLAHRGYGFDQIVNQLSFGTEGLYGTPTYVSATYIYLFILFGAFLEQAGMIRLFTDFAMGLFGHRSGGPAKVSVFSSALMGTITGSGVANVVTTGQFTIPLMKRFGYSPAFAGGVEATSSMGSQIMPPVMGAVAFIMAETINVPYAEVAKAALIPALLYFGSVYWMVHLEARRSHLHGLPPEQCPSAWGALRQRWFLLIPLLVLIALLFSGRTPLYSGMVGLALTAIVILGSAIILRAGNTWLRIAFWVALGVLCSGFFRLGIGIVFLVIAALALACFFIRGGHATLRACVMALAEGARHAVPVGIACTLVGVIIGVISLTGVATTFAGYILDLGRDNLFLSLVLTMLTCLVLGMGIPTIPNYIITSSIAAPALLELGVPLIVSHMFVFYFGILADLTPPVALACFAAAPIAQEKGLKISFWAVRIALAGFVVPFMAVYDPALMMQGDSWAATLYMLVKAIFAVVLWGMASIGHLSAPMPWWERGLAFAAGLLLILALPISDEAGFALGAAVLGWHLWRHRGAAGQPA
>NC_020829|935654:978058|972127_973081_-|WP_015475646.1|DBSCAN-SWA
MIRRTRLALAGAAFLAVCATAQAAPVFINILTGGTSGVYYPVGVGLSQIYSHGIEGSKTSVQATKASVENLNLLQAGRGELAFALGDSVADAWKGEADAGFKTPLKKLRAIAGTYPNYIQIVASKESGITSLADLKGKRISVGAPKSGTELNARAIFKAAGLSYEDMGKVEYLPFAESVELIKNRQLDATLQSSGLGQASIRDLASTMPVSFVAIPAEVVAKIGNNAYLPATIPAKTYDGQDADVPTAAIVNILVTHEGVSDELAYQMTKQLFDNLPRLVTAHAAAKDISLDKAAKNLPIPLHPGAERFYKEKGLLP
>NC_020829|935654:978058|974662_974848_-|WP_015475648.1|transposase|DBSCAN-SWA
MESFFRSLKAERVYLTRYASYQEAKTDLFDYIRFYNHRRRHSTLGYLSPMEFERRNASSSS
>NC_020829|935654:978058|938499_938991_+|WP_015475626.1|DBSCAN-SWA
MKRSIPFLFASLLAACAGEPPTIPQHSFDVHTLAERPSASTRTLADPQGKAVLVTTQPTLTQHDVQQAQLASVADGKPAVQVQFTPDASLRLAHLTREAQGKALAVVIDGQLRLLPKVDHPLTDGRVLLQGFASQVEAETLVRRLNELRDVPVQPEQKSGGQP
>NC_020829|935654:978058|950294_951566_-|WP_015475632.1|DBSCAN-SWA
MICVDCVTPAPLKKLFDTYGTAGDCEYCGRHGHVMESKHLFDYVYERVAENVARKDDLSHYELGLLYHCGSDFIAVSDIDIVLMEWFELGNEPYFSDLCDGVPPEFRVDDAENETHFYDDDGTLEQNFYEDRWKKFVEDVHYKHRYFNAGADHFLDSVFSVLVTEGNQLKPEVVRTIAHGELLYRARHAQNQKQAEEIIGNPAGQFGPTPKHLASSQRMTPNGISALYCALERETCLSEIRSITGDHVVSAALTPIGELKLLDLTVLDRVEPPALTLLDEGFRESLHRKVFLGSLVKKMSRPKARNDELSYLSTQVVFEYLRLRFGKYVDGLVFPSVQTGEAGTNVVLFPEASRLSYVPPTDPVPMAVPPENPFGSPAKLAVVADSIRFHKVTAIETKAQEYSHIYDLFMSDLNRKRLGLNFE
>NC_020829|935654:978058|975524_975818_-|WP_015475650.1|transposase|DBSCAN-SWA
MTQTRRRFPESFKREAVDQVLAGTPLRHVAETLGIAESLLGNWKRQYEQQGEDAFPGNGKQRGESAELRRLRQQLAQVTMERDVLKKALAIFSQPTK
>NC_020829|935654:978058|957677_959336_+|WP_015475636.1|DBSCAN-SWA
MHVKSIRLINFKKFKDDHLEFNDDVNIFVGDNNAGKSTILEALEIALNYNYRGRPFNTEFTPDLFNKSAVQQFLDSDRSSAHLPRLVIEAFIDGVPDYRGANNSLQIDAQGVIVQACFDTSLQDVYADYLKTNPSITSIPIEFYKLEWLDFGWNQIKAVAKKFRALYIDPTRIHPTMGKNQYISTILNTALEKEELVKLTLNYRENQQVFNQSGEVKAVNDGLDAEHLITDKKLSIAASTLPAGSIQTGLQLEVDDVPFQFIGKGEQSNVQIKLAIQNKSKDIDLVMMEEPENHLSYSNLNKLVHYIENQRGTKQLFLTTHSSYVLNKLSINKICLVQSAYQRLHKLDPKVVKTLKRLPGYDTLRVALSGKVILVEGPSDELVLKKIYYRKHDRLPEQDGIDIIVVRGVGFDTFIAVGKEIGTRINVLRDNDGAYQDNVVKARQEYAAFPNIKLISSDNDLAFSLEPAMIYANAADLKTLDAFAEEVLSTQTYNLYKVVGTLEERREFLIDWFRSVRGNGKGARKVDSAIRLFDGTLDFKYPAFLDEVFDFG
>NC_020829|935654:978058|969647_970055_-|WP_015475644.1|DBSCAN-SWA
MTGLCLGLAGVVWASLPLQHFTLAWQHSIEKIRWEEDYQVTSAGLLLGEARVRGNGAGMEIPDGAVLRDGAWHYRRHLPPLQPLHAGRTPEAGDYQLCTEHGCQALAHWLGPPTTKTPAMDFWACETTTETSRPL
>NC_020829|935654:978058|952579_953194_-|WP_015475634.1|DBSCAN-SWA
MAENDMTHRERALRLVQDMGIVRARDFTAAGIPLVYLKRLCDSGDIFRLARGLYQDPNRLGEDAAHDLAEAARRVPNGVISLISALHYHQLTTQLPHAVWMTIPHKARTPTPQGLRLEIVRATGEVMSAGIEHVRVEGVEIPIYCVAKTVADCFKHRRHVGEDVAIEALKDALQKQKTNPSDLMRYAAINRVAGRIAPYIRALQ
>NC_020829|935654:978058|953277_957336_+|WP_041711725.1|DBSCAN-SWA
MTMNQSSPPDELTPRHVRAARALLAWSQQELAKSAGVATSTVADFERGHRTPMANNALAIRNALEAAGISFLPQGAVIGPALPPIAPAERPGIPIRWVTSEDLADWANRNDAVESMPTLLSHLVYATEGAGVWRRFPADESVRFSGWDGLTSGQTSSLYVPKGEAGWEITTQRKDIAGKATNDYRKRTENPAPLDPHDATYVFVSTRPWPSKHEWVSERKKEGVWKDVRAYDADDLVHWIEQTPSVGLWLASRLSKRPVGVRELNDVWEEWSLATVQPLSEELVLSDRDQDAAETLLWLRRSPSMLSLQANTAEEVVAFFHATLRMLPEEASIAYRVRCLVATTADAARALSEAPAPLILLMMEPDPGLAKVLVARGHYVLQCYDERQVSRGDLRTLERPSREGIVFALSQAGVPEARADKLARDCARNLTVLRRLMLGAPGRLPRWADDAPSPALRAALLVGGWDDSFEADCKQISELADLPYERVAADLAPLVGNFDSPLQKLGSTWRVKSPMDAWMLLASHFTGSDVARFESVALAVLGAEDPRFGLTPEERWLAPLREVRPRYSEMLRQGVGQTLILLALWGDKAATAQGAKDSADRIVRTLLENADQARWWSLSGDFRLLAEASPSEFLDALEDSLNRDDPPLGALFVIEDGIGVGTSHLCDLLWALESLAWSPALLTRVSRVLAKLDDIDRTPDRYMNRPRNSLRNIFLLWGPQTFAPLASRLKTLDVLRARESDAAWRLMLGILPRGNDTSIPSPTPRWRDFTPDKVEAVTWNLISRGVLEITKRLISDAGSSAPRWADLIERLPDLVSGPVDVIAELDEAEKSIPDEEGRSVLWAAIRRILHHHRQFPEAEWAMAEEFLSPLEEIYERLTPSDKFQRVSWLFAGGVVVPRPSSGWESEQRDIDELRKQAADSLFRDGGVSAVLELARQIELPTILGKALYESGLSEPDLQSLLEAALLSGSTQERELARGLIAPSFYFKGKEWGDLLVTKALTAGWDSSAVLAILLALPTQAWTWEQARRAGTKLEERYWKAVPVFWSKEQKQDVCYAIDKLISVGRARAAVAFAGRDTTLHLPTAMLVELLNQAVMQPEEATADANEGTMFQYYVGEIFKSLDERDDLEESVLALLEWKYLQVLEHSRRPPKVILESLSTQPRMFVHMLTAAFSPSEESQEAEEHQDQRSTSVARQAYRLLQVWNRVPGTQSDGTIDKKALSAWIDEVLRLAKEKHRKDVALDQIGTILSASPVGADGVWPAEAVRDVIDDLESKTLLNGFYIGKLNRRGATTRLLRDGGALERTEVEKYRKWAKALESANPYTAKVLEMLARRYEAEASHHDDSSERQDWRF
>NC_020829|935654:978058|960716_962153_+|WP_015475638.1|transposase|DBSCAN-SWA
MKRFIEEVSRAQVSLLPECLDDFVAEDNPIRVVEAFVEQLDLVALEFDGVTPAVTGRPSYHPAVMLKVYIYGYLNRIQSSRRLERECQRNLELMWLTGRLAPDFKTIADFRRDNGKAIRNVCRQFVVLCRQLDLFSQSLVAIDGSKFKAVNNRDRNFTHGKLRARMEQIEKSIDRYLAALDTADRTQSDVAEAKTSRLQEKIEKLRQQMQALKEMEQQLREAPDGQVSLTDPDARSMATSGKGTGVVGYNVQTAVDTRNHLIVAHEVTNVGHDRAALATMAKQAREATGSERLSVVADRGYFSGVEILACEQAGITPFVPKPMTSSSKAEGRFGKQDFVYIAADDEYQCPAGQRAIKRFSTVEDGLELDAYWSSACPSCPIRSSCTTSSYRRLKRWRHEAVLEAMQQRLDREPEMMSVRRQTVEHPFGTLKYWMGATHFLTRTLPRVSTEMSLHVLAYNFKRLMSIFGVTGAMEALRA
>NC_020829|935654:978058|951665_952583_-|WP_015475633.1|DBSCAN-SWA
MSVKGVKNAAASISARLLNLARQRGDSFQHIQTRYALERLLFRISQTPEAAGYVLKGAMLFVTWPEHVYRPTRDIDLLGHGDPSPDAILELFRKICRVEVLEDGITFDPTTLSIQPVRERDRYQGICLSLEGQMGSARIPVQVDIGFGDHVYPEPEPQNFPNLLPGLPQARILMYPPETVVAEKFEAMVRFGGLNSRLKDFHDIWVIIRTFSVDLSTLLRAITGTFQRRDATVPADIPLGLTPAFAETAGELWQGFLRRNPPTYQLPPFEDLLAELRQFFGPAIASFERQEFAQGLWDPDRRSWL
>NC_020829|935654:978058|963062_964796_-|WP_015475639.1|DBSCAN-SWA
MNIPPSLSHPWRLRLVILLFGLLSAVLCWRLLELQLHQREFLQAHGDARSLRYLKIPAHRGEITDRRGEPLAVSTPMLTLWANGRELAAAPERWAELANALGQTPAAFAARLQANREREFFYLERGLPPVVGQAILARKVPGVYAREEYRRFYPASDTTSQVVGFTDIDGHGQEGVEYAFDSWLSGVPGRRLVLKDLYGRVVKNLQVVRNAKPGKDLALSLDLRLQYLANRELRRALDQFGAKAGSLVMIDVRTGELLAMANQPSFNPNNRQGLDPAAIRNRALTDVFEPGSTVKPISMCAALESGRWRPSDQVEVWPGSLRIGHYTIRDVTRSEGRILDLTGILINSSNVGMSKVAFDIGGQAIHDVMQRMGLGQYTGLGFPGERVGNLPAYPRWRPAETATLSYGYGLSITAVQLAHAYATLANGGSMMPLSLVRRERAPRPEQVIPEKVAHTVTAMLEQVVESPRGIHRARVPGYHVAGKSGTARKAATGARGYRENAYRSMFVGFGPVSAPRIAISVMIDEPSRDGYFGGKVAAPVFSRVMSGALRILEVAPDNLPQPPLHEATEDSRALASG
>NC_020829|935654:978058|940691_944897_-|WP_086009546.1|DBSCAN-SWA
MATRTALLLLVLLMLGLLFWRLYQEFRSQESFERERVVLHSEQLAQRMSLTLELKALAAQALLQQRDERGDVEGEPALLICLRRIYPAFHSLVRLERNGRARSDSAIGFKDAAAIATLRQRGGQQDYHYAFSEDKGGVFYVWLRATAPGEGDSIIRLDEKLARRGWLAQVRPDTPPWILEDQVRKKVLGRSSGSRPGPLSAASPLEQAQSLDGLPIKNTDWQLRPLFDVQRVRAALLPRLSGELALLLLLAGVTGGALLRLQREQQNLRALTADSRQRLRQAAQALGAIDERVLVTRADGRLAYLNPQAEQLFGIQADQAHHHHLLELLPGLGAQLNGDANLPDSGGTELVRVIHTGQPRLFAVSRRPLDDTLHLPDLPWLLRGDPPQGDQVWVLRDVTEEQQALHILEETRRRYQDIFDGVGVALCVLDLSALRQSLVDLNLRRQSDLQAWIAAHPEHLPQLLRQVRITEINNVAKRLMGISTTEQAWQILLGSAGMRPDGVRSKVLDAVLAGHGMIELEACIRTRQGEQRHLWLQLRVPEMIQDFHAVTLSLSDITSRKQVELSLVEREKFWSDAVRAVPDTLYIHDIAARRVIFSNHNLGHQLGYNGDELRAMGERFWEKVLHPDDAEYYWRVRNLQQVVGDGLLLDSQLRWRHRDGSWHWFDIREQAFTRDAAGRVARLIGVAKDITGTVEAHNSLRESGRRYRMLAESISDVIVSTDAQVRLNYVSPSIQQVFGYNAEWVRQNGFQQVAANPAQLERLTALLERLHDAIGEPTRLAELRENTEPQLFTLDCIHADGHKIPVELRIALMWDDHGCFEGLLGVARDISQQRRAEREMRMAATVFEHSTAAIMVTDPAGYIVQINDSFSRLTGYCAEEVLDQLPRLLTADRQEANQLKHVLDSLRKSGSWEGEILQKRKNGELYPSWVGITAVHDEEGDLVSFVCFFSDISERKASERRIHRLAYYDALTHLPNRTLFQDRLHTALLQAERHQQWVVLMFLDLDRFKPINDSLGHAAGDRMLKEVAERLSHCVSDDDTVARMGGDEFTLLLPGQADRERALRQAIQVAEQILASLARPFTLEGREFFVTASIGVALSPQDGAELSQLMKNADTAMYHAKEMGKNNFQFYQAEMNARALERLELESDLRRAIEQEEFILHYQPQFTGDGRRLTGAEALLRWQHPKRGLIPPAEFVPVLEELGLVAQVGDWLLEQACLQLKAWHRDKVRVPKVSVNLSARQFADGQLGERIAGILKDTGIPPACLELELTESILMSDVSQAMQILSGLKRLGLAIAVDDFGTGYSSLNYLKQFPIDVLKIDRSFVDGLPHGEQDAQIARAIIAMAHSLNLMVIAEGVESHEQLEFLRQHGCDEVQGFLFGRPVPAGQFAALFASNALFLLG
>NC_020829|935654:978058|935654_936740_-|WP_015475624.1|tRNA|DBSCAN-SWA
MSSPRFDPSQYDSQLAEKAARLRELLAPFAAPEPEVFDSPREHYRLRAEFRLWREGEARHYAMFEQGDKHTPILIEEFPIASQRINELMPRLKAAWAEPTLGHKLFQVEFLTTLAGDAMITLCYHRPVDAAWQAAAEKLAAELGVSIVGRSRGKRLVVGRDYVSEELTVAGRTFRYRQPEGAFTQPNGEVCQKMLNWAYEALGQREDDLLELYCGNGNFTLPLATRVRKVLATEISKTSVNAALANLADNAVDNVTLVRLSAEELTQALNDVRPFRRLADVDLKSYAFGSVFVDPPRAGMDPDTCELTRRFDNILYISCNPETLAQNIAQLHDTHQVSRCALFDQFPYTHHMEAGVLLTRR
>NC_020829|935654:978058|975955_976846_+|WP_015475651.1|DBSCAN-SWA
MPRHNFNDLQAFVTVAREGSFTRAAAHLGITQSAVSQVVSALEARLQIRLLTRTTRSVSLTAAGERLMDAIGHRFDEIEAELDALTELRDKPAGKVRITCGDNIIKTTLLPKLIPLLAAYPDIKLEFDINYGFRDIVADRFDAGVSFSGTVAQDMIAMPIGGDLRMAVVAAPSYFAEHPIPRHPNDLAAHRCIDIRFPTYGGVDAWEFERKGKKLRVRVDGQLVFNTTTHIADAAVAGLGIAYLPEDEFDPHLEEGRLIRVLEDWCEPFSGYNLYYPSRRQPSPAFALVLEALRLT
>NC_020829|935654:978058|974823_975528_-|WP_080636198.1|transposase|DBSCAN-SWA
MKFRAIEALAGRYPVAPMCRLLQVSRSGFYAWQQRPPSAREMANRRLSQEIRTIHHEVNGIYGHRRIKAELAAMGHACGRHRVARLMREAGLRVRSRKRWRLVSSSRHALPIAPNHLDRQFASDRANRHWVSDMTYVRTAQGWLYLAVVLDLYSRAVVGWAMHHRMQQALVHAALEMAVARRQPKEEVLLHSDRGSQYCAYDYQALLRRHRIVPSHSRPGTAGTTPRWRASSVR
>NC_020829|935654:978058|973194_974550_-|WP_015475647.1|DBSCAN-SWA
MSDQSANLPSRNLADSEPNVSRARRFYHSRWRLWRQHLAFWVGALLVGLLALAFAWLADQSFALFKRTLGVAPWLPLLVTPAGFALLAWVTQRWFVEAKGSGIPQVIAALESPSRRFRAQVLALPVAAVRMVFTLGALLVGGSVGREGPTVHVGAAVIYAFGRRLGLHGRRTIAGLILAGGAAGIAAAFNTPLAGIVFAIEELSRTFEQRFSGLVLTAVLIGGAVTLGLMGHYSYFGEIGGSLPAGWGWSEVPACALLGGLLGGLYVKLVLPTRVGWLGRMCRLRERFPVRFAGACGLLLALLGLASGNHVFGTGYEETRALLEGQPMTEQSFLLWKFLANVVSYLAGIPGGLFSPSLSIGAAFAPLLAQLPDVNPQTCALLGMGAYLAGVTRSPLTASVIVLELSHSPDLLIPMLAATVMAATVSGWIAPVSLYHALARQILDKLAPNKP
>NC_020829|935654:978058|959328_960507_+|WP_015475637.1|DBSCAN-SWA
MANELWIAGAGSGKTHKIIQDAIEVIDAGGRVLVVTYTTSNQAELRSRFVKVYGRSSDNFVVKGLFSFYLEDLVRPYQNVVFPDRITTTAFTEHNPHLRPGTTKWLPNRGEKIKGVLNPLHYLTSCKTKAYTGFLAKLATLIAKQTKNAPAKRLKDIYQRVFFDEVQDLVGWDYDVIKALSKVMPDSICCVGDFRQTIYTTTFGHKAPQTPVEKIEYFQGLKFHQHSLPRNRRCIQEICDLSDTIHPGLYDKTVSEMKQIPDEVVHHYGAFVVKHSQVGEYIAAFKPQVLRWSSSMGNNYLPPNLSCHTFGSSKGLGFDRVLIFSPEKHLKYLSGDGKAFDKDKTEESRNKLYVAITRARYSLAFVVEDELVVKMPLPLWGGAVQAAVAPVA
>NC_020829|935654:978058|939175_940429_-|WP_015475627.1|DBSCAN-SWA
MFSRDLTLARYDAELFAAMEQEAQRQEEHIELIASENYTSPAVMEAQGSVLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRAKQLFGADYANVQPHAGSQANAAVYLALLSAGDTILGMSLAHGGHLTHGASVSSSGKLYNAVQYGITDAGLIDYDEVERLAVEHKPKMIVAGFSAYSQVLDFARFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRGGLILARKNEEIEKKLNSAVFPGAQGGPLEHVIAAKAVCFKEALQPEFKAYQQQVLKNAQTMASVFIERGFDVVSGGTQNHLFLLSLIKQDITGKDADAALGRAFITVNKNSVPNDPRSPFVTSGLRIGTPAVTTRGFKEAECRELAGWICDILTNMGDESVVDGVREKVKAICAKFPVYGA
>NC_020829|935654:978058|936925_938221_-|WP_015475625.1|DBSCAN-SWA
MLEKLFQLKAHNTNVRTEILAGITTFLTMAYILFVNPSILGETGMDKGAIFVATCLAAAIGSAVMGLIANYPIALAPGMGLNAFFTYTVVLHMGHTWQVALGAVFLSACMFFVISIFRVREWIINSIPLALRSAIAAGIGLFLALIALKESGIVVANQATLVGMGDLAKPAPLLAILGFILIVALEARRVTGAVMIGILAVTFISIAIGVSQFGGVVSMPPSLAPTFLQLDIKGALDIGLFSVIFAFLFVDLFDNSGTLIGVAKRAGLMGKDGHMPKMGRALIADSSAAMVGSLLGTSTTTSYIESAAGVSAGGRTGLTAIVVAVLFLLALFFAPLAGNVPAFATAPALFFVAVLMASGLAEIDWDDLTVAAPVVVTALAMPLTFSIANGIAFGFITWTACKLLSGRFRELNPALVILSILFVIKLGWFNA
>NC_020829|935654:978058|967654_969628_+|WP_015475643.1|holin|DBSCAN-SWA
MNAPSKPRSTLNPPVFYSSAVLILVLVLYASVFQEQAQALFNDVQQWIITNASWFYILAVALILISVVFLAVSRYGDIKLGPDHSEPEYRSSSWFAMLFSAGMGIGLMFFGVAEPVMHFTTPPVGEPGTVAAAREAMKITFFHWGLHAWAIYAMVGLILAYFSFRKGLPLTLRSALYPLIGERIHGPIGHAVDIFAILGTVFGVATSLGYGVLQINSGFHHLFGLPVNPSVQIVLIAITCGLATLSVASGLDKGIRILSELNLGLAAVLLLFVLLLGPTVFLLQTYVQNTGAYLSDIVYKTFNLYAYQPTDWIGGWTLLYWGWWLSWSPFVGLFIARISRGRTIREFVCGVLFVPAGFTLLWMTVFGDSAIHMILTDGVQDLAAIVDQDSSLALFAFLEHFPLSSVVSMVAVLMVVVFFVTSADSGALVVDMLASSGHDHSPLWQRIFWSVSIGVVAIALLLANGLKALQTATIASALPFSIILLASIWGLFRALHLDATRRGLRNQALPSPRQAPHAHGGWQRRLRNIAMLPRRAHVTRFIAEVARPACEEVAVELRKQGYEVTVSEREDGRVSLELDHAGEGRFLYEVRPRAFTTPSFVMRDTEESSDARKYFRAEVHLREGGQDYDIMGWSRDDVISDILDQYERHLHYLHVVG
>NC_020829|935654:978058|965476_965887_-|WP_015475641.1|DBSCAN-SWA
MPSLNPSREQLARFTEEMPAGKPILMLNLLRYRTEADYPPDEGASPCTGREAYARYARVAGAKVAAVGGSVRLLADAHVALIAPDDERWDEILLVRYPSREAFLSMLADSEYRAATVHRTAALADSRLIASTEREA
>NC_020829|935654:978058|948656_950057_+|WP_015475631.1|DBSCAN-SWA
MIRALRDWQFSCINLALEHFTVTPNFFCQATPGAGKTRMAAELASRLLEQGKIDLVLCFAPSCQVVEGFRSTFAAVLGRRLDGRIGAVGAAFTYQAMEYRDEGFWQLLDDYRVLVVFDEIHHCAGHDPLLSNAWGQQILHRIQDRAAFTLALSGTPWRSDDRAIALARYSTPEGQLICDYRYGLKEAIADGVCRSPRIVLLDNQKVKLTEEFGADSSVRLFPSIAKLLGESPVTYEELLRHDEVINPILDLGCSKLNELRQIKPDAAGLVVATDIDHAQQIAVTLEAMGEECRIVTNKTPDVQQVINAFRSSASRWIVAVGMISEGTDIPRLQVCCYLSRIRTELHYRQVLGRVLRRTGESDDQAWLFMLAEPALQGFAERIADDLPDDLAVLSDVLMPGLTAGSRPESIGDFDHIEGTNGADVGDAESGIGSQAVNIISLVGFAAEPAYQVSFSQHYRQQLLACF
>NC_020829|935654:978058|947743_947965_-|WP_080636197.1|DBSCAN-SWA
MDNLAKALGERIRSQRKVCRISQDALALACSIDRSYMGRIERGEVNITVEKLYRIAGELACDPSSLLPKPSEI

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015475624.1|935654_936740_-|tRNA	tRNA (uridine(54)-C5)-methyltransferase TrmA	NA	NA	NA	NA
WP_015475625.1|936925_938221_-	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	6.2e-69	38.7
WP_015475626.1|938499_938991_+	hypothetical protein	NA	NA	NA	NA
WP_015475627.1|939175_940429_-	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	2.0e-101	53.1
WP_086009546.1|940691_944897_-	EAL domain-containing protein	A0A127AWB9	Bacillus_phage	8.9e-16	31.2
WP_080636197.1|947743_947965_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015475630.1|948069_948660_+	hypothetical protein	NA	NA	NA	NA
WP_015475631.1|948656_950057_+	DEAD/DEAH box helicase family protein	I4AZM6	Saccharomonospora_phage	2.4e-42	33.2
WP_015475632.1|950294_951566_-	RES family NAD+ phosphorylase	NA	NA	NA	NA
WP_015475633.1|951665_952583_-	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_015475634.1|952579_953194_-	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	NA	NA	NA	NA
WP_041711725.1|953277_957336_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015475636.1|957677_959336_+	AAA family ATPase	NA	NA	NA	NA
WP_015475637.1|959328_960507_+	UvrD-helicase domain-containing protein	NA	NA	NA	NA
WP_015475638.1|960716_962153_+|transposase	IS1182 family transposase	NA	NA	NA	NA
WP_015475639.1|963062_964796_-	penicillin-binding protein 2	NA	NA	NA	NA
WP_015475641.1|965476_965887_-	DUF1330 domain-containing protein	NA	NA	NA	NA
WP_015475642.1|966004_967363_-	Na+/H+ antiporter NhaA	A0A2H4J5W3	uncultured_Caudovirales_phage	2.4e-63	40.4
WP_015475643.1|967654_969628_+|holin	choline BCCT transporter BetT	A0A2I7QNT1	Vibrio_phage	2.4e-27	28.3
WP_015475644.1|969647_970055_-	DUF1850 domain-containing protein	NA	NA	NA	NA
WP_015475645.1|970051_972079_-	TRAP transporter permease	NA	NA	NA	NA
WP_015475646.1|972127_973081_-	TAXI family TRAP transporter solute-binding subunit	NA	NA	NA	NA
WP_015475647.1|973194_974550_-	chloride channel protein	NA	NA	NA	NA
WP_015475648.1|974662_974848_-|transposase	IS3 family transposase	NA	NA	NA	NA
WP_080636198.1|974823_975528_-|transposase	IS3 family transposase	U5P429	Shigella_phage	6.6e-41	46.0
WP_015475650.1|975524_975818_-|transposase	IS3 family transposase	NA	NA	NA	NA
WP_015475651.1|975955_976846_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_015475652.1|977026_978058_+|transposase	IS110 family transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_020829|1680390:1688193|DBSCAN-SWA
CATGACCTCCCAGCGTACGCGAGAGCGGCTGATCCAGCGCCTGTACGAGGAGGGCCTGTCCAATGCCCATGTGCTCGAAGTGATTCGCCGCACGCCGCGCCACCTGTTCGTCGACGAGGCGCTGGCGCATCGCGCCTACGAGGACACCGCGTTGCCCATCGGGCACAACCAGACCATCTCGCAGCCCTTCATGGTGGCGCGGATGACCGAATTGCTGCTGGCGGCCGGCCCGCTGGACAAGGTGCTGGAGATCGGCACCGGCTCCGGCTACCAGACCGCCGTGCTGTCGCAACTGGTTGAACGGGTGTTCTCCGTCGAGCGTATCCAGGCGCTGCAGGATCGGGCAAAAGAACGACTTGCGGAGCTAAACCTGAGAAATGTTGTCTTTCGTTGGGGCGATGGCTGGGAAGGCTGGCCGGCCCTGGCGCCATACAACGGCATCATCGTCACCGCGGCAGCGGCCGAGGTCCCGCAGGCCTTGCTGGACCAACTGGCGCCCGGTGGGCGGCTGGTGATTCCGGTGGGCGGTGGCGAGGTTCAGCAACTGCTGCTGATCGTCCGTGCCGAGGATGGCTTCCAGCGCCAGGTGCTGGACTCCGTGCGCTTCGTTCCGTTGCTCAACGGCCCGCTGGGCTGAAGTACGCGCAACGGCAGCGGATACAATACCGGCCAGTGGGCCGGGCGTAATTCATGGATAAGGGGGATGGGTGAGCTTGACAGCGACCCTGCGACAACGGAACTGGATCAAGGGCCTGGGCCACGCTGTGCTGGCCATTGCCGTTTGCTCTCTGCTGGCGGCCTGTACTTCCTCGTCACGTAGCAGCACCACCGTGGTCGACCGCGGCGCGTCCGCGCGCAAGGCGGTGACCAGCGGACAGTACGTGGTGCGTCCCGGCGACACCCTGTACTCCATTGCCTTCCGCTATGGCTGGGACTGGAGAGCCCTGGCCGCGCGCAACAACATTTCCGCGCCTTATACCATCCGCCCCGGACAATCGATTCGCTTCGATGGCGGTCCGCCGTCGACACAACCATCCGTCGCAAAAAATGCTACGCCCGTCGCTCCGGCGGTTGTCAATAAGTCGACTTCCACGAGCTCCAGCGCCAGTAAACCGACCCCGTCGACCGCTGCGCCTTCATCTCAAGCCAGCACCGGCAGTGCAACCCCGGCCACGTCGGGCGGTGGTGTCAGTGGTTGGATATGGCCAACCAATGGCACCCTGATTGGGCGTTTTGCATCAAACGGCAGTTTGAATAAAGGGATTGATATAGCCGGGCAATTGGGCCAGCCTGTCCTGGCTGCGTCTAATGGCACGGTGGTGTACGCCGGTAGTGGTTTGCGGGGCTACGGCGAACTCGTGATCATCAAGCACAGCGATACCTACGTAAGCGCCTACGGTCACAACCGCAGGTTGCTGGTGCGGGAAGGGCAACAGGTCAAAGTTGGGCAGAGCATTGCCGAGATGGGCTCCACAGGGACTGACCGGGTGAAGCTGCACTTTGAGATTCGCCGCCAGGGTAAGCCTGTAGATCCGCTGCAATACCTGCCAAATCGTTGACGCTTGCTGTTCCCCTGCGTAGGTGAGCGGGCCCTGGTGTCCTAAGGATAAGGACGCACCTGGGCTTGTTGTCGAACTCAGCAAGGGATAACGACATGGCACTTAAAAAAGAAGGGCCGGAGTTTGACGTCGATGATGAAGTGCTCCTTCTGGAGCCCGGCATCATTTTTGAAGAGTCGCTTGCCGAAGAGCAGGTATCGCTTCAAGTCACTCCCAAGGCTTCCCCTCTCTCCTCTCTCAAGCAACACAAGCACATCGATTACAGCCGGGCGCTCGACGCTACCCAGTTGTATCTGAACGAAATCGGCTTCTCGCCGCTGCTGACCCCGGAAGAAGAAGTCCATTTTGCGCGCCTTGCGCAAAAGGGCGATCCTGCCGGTCGGCGGAGAATGATCGAGAGCAACCTGCGCCTGGTGGTGAAGATCGCGCGACGTTATGTCAATCGCGGCCTCTCGCTGCTCGATCTGATCGAAGAGGGCAACCTCGGGTTGATCCGAGCGGTGGAAAAGTTCGACCCGGAGCGCGGCTTCCGCTTCTCCACCTATGCGACCTGGTGGATTCGACAGACCATCGAACGGGCCATCATGAACCAGACCCGCACCATCCGCCTGCCGATCCATGTGGTCAAGGAACTCAACGTCTACCTGCGGGCGGCTCGCGAGCTGACCCACAAGCTGGACCACGAGCCTTCGCCCGAGGAAATCGCCAACCTGCTCGAGAAACCGGTGGGCGAGGTCAAGCGCATGCTGGGCCTCAACGAGCGGGTGACCTCCGTGGATGTCTCGCTTGGCCCGGACTCCGACAAGACGCTGCTCGACACCCTTACGGACGATCGGCCTACCGATCCCTGCGAGCTGCTGCAAGACGATGATCTCAGCGAGAGCATCGACCTGTGGCTCTCGGAACTGACCGACAAGCAGCGTGAAGTGGTGATTCGCCGCTTCGGTCTGCGCGGCCACGAAAGCAGCACACTGGAAGAGGTTGGGCAGGAAATCGGCTTGACCCGCGAACGCGTCCGCCAGATTCAGGTCGAGGCACTCAAGCGCTTGCGCGAGATCCTCGAGAAGAATGGTCTCTCCAGCGACGCACTGTTCCAGTAAACAACAGTCGACCTCGAAAAAGCCCGGATAATTCCGGGCTTTTTATGCGTCGTGATGTAAGCATTCGCTTACATCGTGTGTGAGTGTTCAGCTTGAGATATTGCTCGCTTGAGCTGAATTATTTTCTATATTTTTGTTTTATAAGGGTTTTTATTTTTGTCGTCAGTACGCGAAGAGGACGGCGAGGTGAAACTGCCTCGGTTGCCAAGGCGCGGAGGTTGAGTAATATCACTCCTGCGTACAAGGAAAGGCGCATGCCGGTAAGGATGTCGGTCAGGACATCGCAGGATGCGATTCATCAGGATGATGAACCAGGGAAGAAAGAGTGGGCGGGTTATCCCGCCCCTTTTTTTGCCCGCAGAAAAGTGACGTTCTGGATGCAGAAAGGCCCGCACTGGGCGGGCCTTTTCTGTTTTTGCTGGTAGCGCAGATCAGCGCTCCAGATACTGCATCTTGTTCGGCTTGCCGTCCCACTCTTCGGCGTCCGGCAACGAATCCTTCTTCTCGGTGATGTTCGGCCAGACGTCGGCCAGATCCTTGTTCAGCTCGATGAACTCCTGCATGCCATCCGGGACCTCGTCCTCGGAGAAGATCGCCTGTGCCGGGCACTCCGGTTCGCACAGGGCGCAGTCGATGCACTCATCCGGATGGATGACCAGGAAGTTCGGGCCTTCGTAGAAGCAGTCCACCGGGCATACTTCCACGCAGTCGGTGTATTTGCACTTGATGCAGTTGTCGGTGACGACGAAGGTCATTTCTAATTTTCTCCTCAGGCGGGCGGCTAAGCGCGCGCGATTCTAACAGCTTGTTTCGCGGTCCGTCAGACTCGCATCTTCCATGCATATAACAATTCGAGAGCTTGGCGCGGTGTCAGGTCATCCGGGCTGACGCGCATCAGCTCTTCGACGATGGGGTGCGGCAGGCTGGCAAACAGGTCGCTCTGCAGTGGCGCCGGGCTTTTCGGATCGTTCGAGCGTGGAGTTTCGTGGGGCAGGCTGGTGGTTTCCAGGCGCGACAGGTGTTCGCGGGCGCGCTGAATTACCGCACCCGGCACACCGGCCAATTGTGCGACTGCCAGGCCGTAGCTCTGGCTGGCCGGGCCGGGCAGTACGTGGTGCAGGAACACGATGCGCTCGTTGTGCTCGGTGGCGTTCAGGTGAACGTTGGCGACCGCCGGCTCGCTTTCCGGCAACACGGTCAGTTCGAAGTAGTGGGTGGCGAACAGCGTGAAGGCGCGCAGCTTGGCCAGGTGTTCGGCCGCGGACCATGCCAGCGACAGGCCGTCGAAGGTACTGGTGCCGCGACCCACTTCGTCCATCAGCACCAGGCTGCGGTCGCTGGCGTTGTGCAGGATGTTCGCGGTCTCGCTCATCTCCACCATGAAGGTGGAGCGGCCGCCGGCGAGGTCGTCGGAGGAGCCGATGCGGGTGAAAATGCGGTCCACCAGGGACAGTTCGCAGCGCGCGGCGGGGACGAAACTGCCGATGTGCGCTAGCAGAACGATCAGCGCCGTTTGCCGCATATAGGTCGATTTACCACCCATGTTCGGGCCGGTAATCACTAGCATGCGGGTGTCCTGGTCGAGGTTCAGGTCGTTGGCGACGAACGGCGTATCCAGCACCTGCTCGACTACCGGATGGCGGCCTTGCTCGATGAGGATGCCGGACTCTTCGACGAAGCGCGGGCGGTTCAGGTCGAGGTTCAGTGCGCGCTCTGCGAGGTTGGACAGCACATCCAGCTCGGCCAGGGCAGCAGCGGTGTCCTGCAGCGGCGCCAGTTGGCCGATCAGCAGTTCCAGCAGTTCTTCATAAAGCTGCTTCTCCCGGGCGAGGGCACGGCTCTGGGCCGACAGCGCCTTGTCTTCGAAGGCCTTCAGCTCCGGCGTGATGAAGCGCTCGGCACCTTTCAGGGTCTGGCGGCGAATGTAATCGGCCGGGGCCTGCTCGGCCTGCACGCGCGGCAATTCGATGTAGTAGCCGTGGATGCGGTTGTAGCCGACCTTCAGGTTCGGCAGGCCGGTGCGGGCCTTTTCGCGAGTCTCCAGGTCCATCAGATACTGGCCGGCGTTTTCGCTGAGCATCTGCAGTTCGTCCAGCTCGGCGTCGTAGCCGCGGGCAATTACACCGCCGTCGCGGATCACCGCCGGCGGGTTCTCGATCACGGCGCGGGCCAGCAAGTCGGCCAGTTCCGGGTAGGTGCGGATGCTGCTGGCCAGTTCGCCCAGGTGCGGGGCTTCCAGCTCGGTCATACCGTTCTGCAGTTCCGGCAGCGCGGCGAGTGCGTCGCGCAGGCGGGCGAGGTCGCGCGGGCGGGCGTTACGCAGGCCGATTCGAGCGAGGATGCGCTCGACGTCGCCGATTTCCTTCAGTTGTGGCTGAAGGATTTCGAAGCGATAGCGCTCCAGCAGGCAGGCAATGGACTCCTGGCGGGCTTCGAGGACGGCGCGGTCGCGCAGCGGGCGGTTCAGCCAGCGGGTCAGCAGGCGGCTGCCCATTGCGGTCTGGCACCGATCGACCACCGATTGCAGGGTATTGTCGCGGCCGCCGGCGAGGTTGGTGTCCAGCTCCAGGTTGCGGCGGCTGGCGCCGTCGAGGATGACGGTGTCGTCAATGCGTTCATGGCGCAGGCTGCGCAGGTGCGGCAGGGCGGTGCGCTGGGTTTCCTTGGCGTAGGCCAGCAGGCAGCCGGCGGCGCCGATGGCCAGGGTCAGTTCCTGGCAGCCGAACCCCTTGAGATCCTGCACGCCGAACTGCTGGCACAGGCTCTTTTTCGCCGAGTCGCGATCGAAGTCCCAGGGCGCGCGACGGTGCGCGCCACGGCGTTTTTCCGCCGGCAGGCCCTGGGGCCAGTCGTCGGGGATCAGCAGCTCGGCGGGATTCAGACGCTCCAGTTCGGCGAGCAGGGTTTCCCAGCCTTTTATTTCCTGGACGTTGAAGCGGCCGCTGGTGATATCCAGCACGGCGAGGCCGAACAGGCGCTCATCGCCCAGCACGGCGGCGATCAGGTTATCGCGGCGTTCGTCGAGCAGGGCTTCGTCACTGACGGTGCCGGGGGTGAGGATGCGCACTACCTGGCGCTCCACCGGTCCCTTGCTGGTGGCCGGGTCGCCGATCTGCTCGCAGATCACCACCGATTCGCCGAGCTTCACCAGCTTGGCCAGGTAGCCTTCGGCGGAGTGGAAGGGAATGCCGGCCATGGGAATGGAGTTGCCGGCGGACTGGCCACGTGCGGTCAGGGTGATGTCCAGCAGCTTGGCGGCCTTCTTGGCGTCCTCGTAGAACAGCTCGTAGAAGTCGCCCATGCGGTAGAACATCAGCTGGTCCGGGTGCTGGTTCTTCAGCCGCCAGTATTGTTGCATCATGGGGGTGTGAGCTGAGAGGTCGCTTTGACTCATGGCTTCTGGCTGTCCGGCTTCAACATGCAAAAGCGCCTAGTGTACGGTATCCGCCTGACCTTCTTTAACCCCGGAGCGCAGCGTGCCCGTCACCGATTCCTTTATTACCGATCTTTCCATCACCGAACTGGCTGCCCGGCTGGGCGCACGACTCGTCGCCAACCGGCTGCGCGTCACCACTGCCGAATCCTGCACGGGGGGTGGCATCGCCGAGGCGATCACCCGTATTTCCGGCAGCTCTGCCTGGTTCGAGGCAGGCTACGTTACCTACTCCGACAGCCAGAAGACGCGCCAGCTGGATGTGCCGGCTGAGCTGTTCCCGCGAGTGGGCGCGGTGAGCCGCGAAGTGGTCGAGGCGATGGTCGCCGGCGCCTTGCCGCGCAGTGGGGCGGATATTGCCGTAGCGGTCAGCGGCGTTGCCGGGCCGGATGGAGGTTCTGCCGAGAAGCCCGTAGGCACCGTCTGGTTGGCCTGGAGGAAAGGCGAACAGGTGTTCAGCGAACGCCGTCTGTATGCCGGTGATCGGGAGGCGGTGCGCCGGCAGACCGTGGCGACGGCTCTGGCCGGGCTGTTGCGACTGGCGGACGGGGAAAATCCGCTCCAGGGGTAGGCGAGCGGCTTGCCCTGTGGAATAATACTGTCTACTTATACAGTTGTTCGTGGCCGTCCGGCCCCCTGACTTCGCGAGGACTTCAATGGACGAGAACAAGAAGCGCGCCCTGGCCGCGGCCCTGGGACAGATCGAACGCCAATTCGGCAAAGGTGCGGTCATGCGCATGGGCGACCATGAGCGCCAGGCTATCCCCGCCATCTCCACCGGCTCGCTGGGCCTGGACATCGCGCTGGGCATCGGCGGTCTGCCGAAGGGCCGAATCGTCGAAATCTACGGCCCGGAATCCTCGGGTAAGACCACCCTGACCCTGTCGGTCATCGCCCAGGCCCAGAAGGCCGGCGCCACCTGCGCCTTCGTCGATGCCGAACACGCGCTGGACCCGGACTACGCCGGCAAGCTGGGCGTCAACGTCGACGACCTGCTGGTTTCCCAGCCGGATACCGGCGAACAGGCTCTGGAGATCACCGACATGCTGGTGCGTTCCAACGCCGTTGACGTGATCATCGTCGACTCCGTGGCGGCCCTGGTACCCAAGGCCGAAATCGAAGGCGAGATGGGCGATCAGCACGTCGGTCTGCAGGCGCGCCTGATGTCCCAGGCCCTGCGCAAGATCACCGGCAACATCAAGAACGCCAACTGCCTGGTCATCTTCATCAACCAGATCCGCATGAAGATCGGCGTGATGTTCGGCAACCCGGAAACCACCACCGGTGGTAACGCGCTGAAGTTCTACTCCTCCGTTCGTCTCGATATCCGCCGTACCGGCGCGGTGAAGGAAGGCGACGAGGTGGTCGGCAGCGAAACCCGCGTCAAGGTCGTGAAGAACAAGGTCGCACCGCCCTTCCGTCAAGCCGAGTTCCAGATCATGTACGGTCGTGGCATCTACCGCACCGGCGAGATCATCGACCTGGGTGTGCAACTGGGCCTGATCGAGAAGTCCGGCGCCTGGTACAGCTACCAGGGCAGCAAGATCGGCCAGGGCAAGGCCAATGCCGCCAAGTTCCTGGAAGAGAACACCGAGATCTGCAACACCCTCGACAAGGCCATCCGTGAGCAACTGCTGACCAACCAGCCGGCGCCGACCAAGGCCGAGCTCGCGGCGGCGGAAGCCGAAGCGGAAGCGGAAGCCGACTACTGA

Protein sequences of DBSCAN-SWA_2

>NC_020829|1680390:1688193|1681102_1681948_+|WP_080636265.1|DBSCAN-SWA
MTATLRQRNWIKGLGHAVLAIAVCSLLAACTSSSRSSTTVVDRGASARKAVTSGQYVVRPGDTLYSIAFRYGWDWRALAARNNISAPYTIRPGQSIRFDGGPPSTQPSVAKNATPVAPAVVNKSTSTSSSASKPTPSTAAPSSQASTGSATPATSGGGVSGWIWPTNGTLIGRFASNGSLNKGIDIAGQLGQPVLAASNGTVVYAGSGLRGYGELVIIKHSDTYVSAYGHNRRLLVREGQQVKVGQSIAEMGSTGTDRVKLHFEIRRQGKPVDPLQYLPNR
>NC_020829|1680390:1688193|1683479_1683803_-|WP_015476292.1|DBSCAN-SWA
MTFVVTDNCIKCKYTDCVEVCPVDCFYEGPNFLVIHPDECIDCALCEPECPAQAIFSEDEVPDGMQEFIELNKDLADVWPNITEKKDSLPDAEEWDGKPNKMQYLER
>NC_020829|1680390:1688193|1686524_1687052_+|WP_015476294.1|DBSCAN-SWA
MPVTDSFITDLSITELAARLGARLVANRLRVTTAESCTGGGIAEAITRISGSSAWFEAGYVTYSDSQKTRQLDVPAELFPRVGAVSREVVEAMVAGALPRSGADIAVAVSGVAGPDGGSAEKPVGTVWLAWRKGEQVFSERRLYAGDREAVRRQTVATALAGLLRLADGENPLQG
>NC_020829|1680390:1688193|1687137_1688193_+|WP_015476295.1|DBSCAN-SWA
MDENKKRALAAALGQIERQFGKGAVMRMGDHERQAIPAISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSVIAQAQKAGATCAFVDAEHALDPDYAGKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAVDVIIVDSVAALVPKAEIEGEMGDQHVGLQARLMSQALRKITGNIKNANCLVIFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLDIRRTGAVKEGDEVVGSETRVKVVKNKVAPPFRQAEFQIMYGRGIYRTGEIIDLGVQLGLIEKSGAWYSYQGSKIGQGKANAAKFLEENTEICNTLDKAIREQLLTNQPAPTKAELAAAEAEAEAEADY
>NC_020829|1680390:1688193|1683868_1686442_-|WP_177324581.1|DBSCAN-SWA
MSQSDLSAHTPMMQQYWRLKNQHPDQLMFYRMGDFYELFYEDAKKAAKLLDITLTARGQSAGNSIPMAGIPFHSAEGYLAKLVKLGESVVICEQIGDPATSKGPVERQVVRILTPGTVSDEALLDERRDNLIAAVLGDERLFGLAVLDITSGRFNVQEIKGWETLLAELERLNPAELLIPDDWPQGLPAEKRRGAHRRAPWDFDRDSAKKSLCQQFGVQDLKGFGCQELTLAIGAAGCLLAYAKETQRTALPHLRSLRHERIDDTVILDGASRRNLELDTNLAGGRDNTLQSVVDRCQTAMGSRLLTRWLNRPLRDRAVLEARQESIACLLERYRFEILQPQLKEIGDVERILARIGLRNARPRDLARLRDALAALPELQNGMTELEAPHLGELASSIRTYPELADLLARAVIENPPAVIRDGGVIARGYDAELDELQMLSENAGQYLMDLETREKARTGLPNLKVGYNRIHGYYIELPRVQAEQAPADYIRRQTLKGAERFITPELKAFEDKALSAQSRALAREKQLYEELLELLIGQLAPLQDTAAALAELDVLSNLAERALNLDLNRPRFVEESGILIEQGRHPVVEQVLDTPFVANDLNLDQDTRMLVITGPNMGGKSTYMRQTALIVLLAHIGSFVPAARCELSLVDRIFTRIGSSDDLAGGRSTFMVEMSETANILHNASDRSLVLMDEVGRGTSTFDGLSLAWSAAEHLAKLRAFTLFATHYFELTVLPESEPAVANVHLNATEHNERIVFLHHVLPGPASQSYGLAVAQLAGVPGAVIQRAREHLSRLETTSLPHETPRSNDPKSPAPLQSDLFASLPHPIVEELMRVSPDDLTPRQALELLYAWKMRV
>NC_020829|1680390:1688193|1680390_1681026_+|WP_015476289.1|DBSCAN-SWA
MTSQRTRERLIQRLYEEGLSNAHVLEVIRRTPRHLFVDEALAHRAYEDTALPIGHNQTISQPFMVARMTELLLAAGPLDKVLEIGTGSGYQTAVLSQLVERVFSVERIQALQDRAKERLAELNLRNVVFRWGDGWEGWPALAPYNGIIVTAAAAEVPQALLDQLAPGGRLVIPVGGGEVQQLLLIVRAEDGFQRQVLDSVRFVPLLNGPLG
>NC_020829|1680390:1688193|1682043_1683048_+|WP_015476291.1|DBSCAN-SWA
MALKKEGPEFDVDDEVLLLEPGIIFEESLAEEQVSLQVTPKASPLSSLKQHKHIDYSRALDATQLYLNEIGFSPLLTPEEEVHFARLAQKGDPAGRRRMIESNLRLVVKIARRYVNRGLSLLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMNQTRTIRLPIHVVKELNVYLRAARELTHKLDHEPSPEEIANLLEKPVGEVKRMLGLNERVTSVDVSLGPDSDKTLLDTLTDDRPTDPCELLQDDDLSESIDLWLSELTDKQREVVIRRFGLRGHESSTLEEVGQEIGLTRERVRQIQVEALKRLREILEKNGLSSDALFQ

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015476289.1|1680390_1681026_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	7.1e-42	53.5
WP_080636265.1|1681102_1681948_+	peptidoglycan DD-metalloendopeptidase family protein	A0A0S2SXL7	Bacillus_phage	1.3e-06	34.6
WP_015476291.1|1682043_1683048_+	RNA polymerase sigma factor RpoS	G8CLC7	Synechococcus_phage	1.6e-35	37.6
WP_015476292.1|1683479_1683803_-	ferredoxin family protein	NA	NA	NA	NA
WP_177324581.1|1683868_1686442_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	1.2e-26	22.8
WP_015476294.1|1686524_1687052_+	CinA family protein	B5TK85	Pseudomonas_phage	4.3e-53	73.0
WP_015476295.1|1687137_1688193_+	recombinase RecA	A0A0S2MVG1	Bacillus_phage	6.7e-114	62.5

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NC_020829|3069715:3077725|DBSCAN-SWA
ATCAGTCGTCGCTACCCATGATGCCGAATATCTGCAACAAGCTGAGGAACAGGTTGTAGATCGACACATACAGGCTGATGGTAGCCATGATGTAGTTGCGCTCGCCACCGTGGATGATTGCGCTGGTCTGGAACAGAATCATCGCCGAGGAGAACAGCACGAAACCGGCGCTGATCGCCAGTTGCAGGCCGCTGATCTGGAAGAACAGCGAGACCAGTACGGCACCCATCAGTACAAAGAAGCCCGCAGTGATGAAGCCGGACAGGAAGCTCATGTCCTTGCGAGTGGTCAGTACATAGGCGGACAGACCGAAGAACACCAGTGCCGTCATGAAGAAGGCCGACGAAATCACACTCGCGCCATTGGCCATGCCCAGGTACAGATTGAGGATCGGGCCGAGGGTGTAGCCCATGAATCCGGTGAGGGCGAAGGTGCTGAGCAGGCCCCAGGCGCTGTTGCGCAGCTTCACGGTGAGGAAGAACAGGCCGTAGAAGCCCAGCAGCACCACGAAGATGCTCGGATACGGCAGACGCATCTGCTGCGAGGCGAAAGCCACCAGTCCACTGAAGGCCAGCGTCAGCGCGAGCAGGCCGTAGGTATTGCGCAGGACGCCGCTGACCTCTTTCTGCTCCACGGCTGTGGAGTCGAGATATTGCCGTTCTTGCATGTCGAGACACTCCTGTTTAAGCGGGATACGGGTCCATGACCGTAGTGCCACTCATCATAACAGAGGCAAATGGACCTCGAATCACCAGAGTTTGACAGTGTGTTGCGATCCGGTACTATGGCGCCCCGCTCATGCGGAAGTGTGGCCGAGTGGTTTAAGGCAACGGTCTTGAAAACCGTCGACGGGAAACTGTCCCAGAGTTCGAATCTCTGCGCTTCCGCCATTATTCAAGGCCCTGATTTTCAGGGCCTTTTTCATTCCTGGGCAACGCTATTCGGCCTTCTCCAGAAGGCTGATTTCTTGATGAATCCCAGAATAAAACGGCACGGGTCCCACAACTTTTAACCAGATCCTCTCCCCTCCTCGCCCGCCCTGGGCACCCTACTATCCTCCTCACCGGTCTGCCCCGGAACTGGTGGACAGGTAGTTAAGAGCTACTGCTCGCATTTCGTCGCTCGAACTCCATCGGGCTGAGATAGCCCAGCGTCGAGTGACGGTGACGGTGATTGTAAAAGGCTATGTCTGAGTTAACTGTTGCGGAAAATCCTTCAGAAGAACGCAGCGCCTGTGGCAGCGGGATTGCCGGCGATGCTTTTGCGTTGCCGGCTTTCGCGAGCAAGCTCGCTCCTACAAAGGGCTGCAGCCCGACACAACACATAACTAAGACATAGCCTTTGCGTTTCTGCTGCGCGGCAAAAAACGACGCAGTGCCGTATCATCCTGCGAAATCCGCCGCCAAGGCCTGCTCCATGAAGTTCGTCATCGCCCTCTTCTCCCCGCCGCATTCACCGGCAGCCCGACGCGCCCTGCGCTTCGCCGAGGCTGCGCTGGCCGGCGGGCATGAAATCACCCGGCTGTTCTTCTACCAGGACGGCGTGTACAGCGCTTCGGCCAATGCTGTCGCCGGCCAGGACGAACTGGACGTAGCCGCTGCCTGGTCCCGTTTCGTCGCCGACAATCAACTGGATGGCGTAGTTTGCATCGCCGCCGCCCTGCGCCGTGGCGTGCTGAACAACGAGGAAGCCAACCGTTATTCCCGCCCCGCCGCCAACCTGCAGGCGCCCTGGGACCTTTCCGGTCTCGGCCAGTTGCATGAAGCGGCGCAACTGGCGGACCGCCTGGTCTGCTTCGGAGGCGACTGATGGCCAAGTCCCTGCTGATCATCAGCCGCCAGGCTCCCTGGGCCGGCCCCGCCGCCCGCGAAGCACTGGACATCGCCCTGGCCGGCGGCGCCTTCGATCTGCCAATCTCGATGCTGTTCCTCGACGACGGCGTCTTCCAGCTCGCCCCCGGCCAACGCCCTAGCAATCTTGAACAGAAGGACCTGCAGGCCAACCTGCAAGCCCTGCCGCTGTTCGGCGTGGAAGCCCTCTATGTCAGCCAGCGCAGCCTCGGTGAGCGCGGCCTGGACGCCGCCAGCCTGACACTCCCCGCGCAAGCGCTGGACGCCGCCGCCCTGCGCGATCTGCTGCAAACCCACGACCAGGTGATCACGATCTGATGGCTACTCTCCACCTGCTCTCGCACTCCCCCTTCAATGACGGCCGGCTCGCCAGTTGCCTGCACCTGCTCGGCCCGGACGACGGCCTGCTGCTGAGCGGCGAGGCCGTCTACGCCCTGCGCGACGGCACCGCGCCCTGCCAGGTGCTGGAGCTGATGCCCGCAACCAACGGACTCTTCGCCCTGCTGGAAGACCTGCAGGCGCGCGGCATGGATGATGTTCCCGCCCGCGTCATCGCGGTCGACTATCCCGGTTTCGTCGAACTCTGCACCCGCTTCGACAAGGTGAACGCCTGGCTATGAGCACCCTATTGGTCAACGGACAATCCCTGCCGCTGGACAAGGACGGCTACCTGGCGCAGCTGGACGACTGGAGCGACGCCGCCGCCGAGGCCCTGGCGCACAACGAAGGCATCCACCTGACACCCGAGCATTGGGAAATCCTCCTACTGCTGCGTGAGTTCTACGGCGAGTTCCAGCTCTCCCCGGCCAATCGGCCACTGATCAAGTACGTCGCCCAGCGCCTGGGCACGGAAAAAGGCAGCAGCCTGCACCTCAACCTCCTGTTCAAGGGCACCCCGGCCAAGCTTGCCGCCAAGCTCGCCGGCCTGCCGAAGCCGACCAACTGCCTATGACCGCCTCCCCGCTCGTCCTGCAGACACCTGAAGAACATCCGTTCGCCCAGTTCGTGCGCATTCTCGGCAAGGGCAAGCGCGGCGCGCGCGGCCTGACCCGCGAGGAAGCCCGCGAAGCGCTGGGCATGATCCTCGACGACAAGGTCGAGGAAGCCCAGCTGGGCGCCTTCCTGATGCTGCTGCGGCACAAGGAGGAAAGCGCCGAGGAGCTGGCCGGCTTCACCGAAGCCGTACGCAGTCGCCTGCAGACACCGAAGATCGCCGTGGACCTGGACTGGCCTAGCTACGCCGGCAAGAAGCGCCACCTGCCCTGGTTCCTGCTGGCCGCCAAATGCCTCGGCGGCAGCGGCACTCGCATCCTGTTGCACGGTGGCGGCGCCCATACCGCCGGCCGGCTCTACACCGAGCAATTGCTGGAACAGCTCGGCCTGCCGCTGTGCCGCGACTGGAGCTCGGTCAGCGAAGCGCTGGACGCCAAGGGCATCGCCTTCGCTCCGCTGGCGGACTGGATGCCGCGCATGCAGCGGATGATCGACCTGCGTAATACTCTTGGCCTGCGCTCGCCGATGCACTCCGCCGTACGCCTGATCAACCCGCTGGGCGCCACCTGTGTGCTGCAGAGCATCTTCCACCCCGGTTACCAGGCGGTGCACCGCGAAGGCAGCCGTCTGCTCGGCGACTACGCCATCGTCATCAAGGGCGAAGGCGGCGAGATCGAAGTGAACCCGGACGCCACTTCGCACCTGTACGGGTGCCGCGCTGGCGAAGCCTGGGACGAGGAATGGCCGGCGCTTTCGCCGCTGCGTCACGTCAAGCCGGAAACCCTCGATCCGCAGCATCTGGCTGCCGTGTGGCGCGGCGACGAAGAGGACGCTTATGGCGAACTGGCCGTGCGCGCGACCATGGCACTGGTGTTGCGTGCAATGGGATTACAGCGAGACGAGGCCTTCGCGGAAGCTGATAAACGCTGGGCTGCGCGCGATAGATCGATTTAATCGATACCTGGAATCCTGTTTTTGCGCCAATCAATCGACTCTTAGCCGATAGACTGATCCCATCTCCCCCGCTTTCAGGAGCACGCAGATGGGACAGTTGATCGATGGCCGCTGGCATGACCAGTGGTATGACACCAGCAAGGACGGTCGCTTCCAGCGCGAAAACGCGCAGCGCCGCAACTGGATCACCGCCGATGGCCAGCCCGGCCCCAGCGGCGAAGGCGGCTTCCGCGCCGAGGCCAGCCGCTATCATCTCTACGTGTCCCTGGCCTGCCCTTGGGCGCACCGCACGCTGATCTACCGCCAACTCAAGGGCCTCGAGTCGCTGATCGACGTATCGGTGGTCAGTTGGCTGATGCTGGAAAATGGCTGGACGTTCGACAAGACCCTCGGCTCCACCGGCGACAAGCTGGACGTCCTGGACTTCCTGCATCAGCGCTACACTAGGGACGATGCGCACTACACCGGCCGCGTCACCGTGCCGGTACTGTGGGACAAGCACGAGCAGCGCATCGTCAGCAACGAATCGGCGGAGATCATCCGCATGTTCAACTCAGCGTTCGACGGGATCACCGGCAACCGCCTGGACCTCTACCCCGAGCCGCTGCGCACACAGATCGACGAATTGAACGAGCGCATCTACCCGGCGGTGAACAACGGCGTGTACCGCGCCGGCTTCGCCACGACGCAGGACGCCTACGAAGAGGCCTTCAAGACGCTGTTCGGCGAACTGGACCGGCTGGACGAGCGCCTTGGCAAGCAGCGTTACCTGACCGGCGAGTACCTGACCGAAGCCGACGTGCGCCTGTTCACCACGCTGATCCGCTTCGATGCGGTCTACCACGGCCACTTCAAGTGCAACCTGCGGCGCCTGGCGGACTACCCGAACCTGTCCGGCTGGCTGCACGAGCTGTATCAGTTGGACGGCGTTGCCGGAACCGTGGACTTCCAGCACATCAAGAACCACTACTACGCCAGCCACCGCACCATCAACCCCACCGGCGTCGTACCGCTGGGGCCGCAGCAGGACTTCACCGGGCCGCACGGGCGGGAGCATCTGCCGGGCAAGGGCATCGCGCGCAAACGCTGATCACTGCGTGTGGGATGAACGCAATCGTAGGAGCGGAGTCCATCCGCGATGCTCGTGTCGAAATCGCGGGCAAATCCGCTCCTGCAAAAGCCAGCTAGGGCGGCGCCAGGCATCAGATCGGCTTGTCGATGCCGTCGTAGACCTTCTGCAGCGCGTCGAGGCGCTCCTGGTAGCGTTGTTTCAGGCAGGCCTTGTCCGTACCACAGGCGCGACGCTGCTCCAGCCACGCGAGCTGCGAATCGCCCAGATTGCCGCGCATGCCCATCGCGAACAGCCCTCTGAGCAGGCGATAGGTCGTGGCCATCTGCACATCCAGCTCGGACAGCTGGCGGTCGGCGCAGATGGCCTTCTCATCAGCCTGTTTCGCCTTGCGGCAGTCGAAGCTGGCGGCGGAGGCCGGCAACACGACGAAACCCAGGGCGCAAGCGACGCCCAGTGCCACCCCATGCACCGTCCTCATCGCTGCCCTTCGAACCAGGCGAGCTTGTCGCGCAGTTGCACCACTTCCCCGACTATCACCAGGGTCGGCGCATGCACTTCGTGCTCGGCCACCAGCTGCGGCAGGTTCGCCAGGGTGCCAGTGAACACGCGCTGGTGCACCGTGGTGCCCTGCTGGATGAGCGCCGCCGGCGTATCGGCGGAACGACCGTGACGCACCAGTTGCTCGCAGATGACCGGCAAGCCGACCAGGCCCATGTAGAACACCAGGGTCTGCCCGGGGGCGACCAGATCGTTCCACGGCAGGTCGGTGCTGCCGTCTTTCAGATGGCCCGTCACGAAGCGCACGGACTGCGCGTAATCACGATGAGTCAGCGGAATACCGGCGTAGGCCGCGCAACCGCTGGCCGCCGTAATACCCGGCACGACCTGGAACGAGATGCCATTGGCCGCCAGTTCGTCGATCTCCTCGCCACCACGGCCGAAGATGAACGGATCGCCGCCCTTCAGGCGCAGCACGCGCTTGCCCTGCTGGGCCAACTCGACCAGCCTGCGATTGATCTCGTCCTGCGGCACGGCGTGGTCCGCGCGGCGCTTGCCGACGTAGAGTCGGTCGGCATCGCGACGGCACAGCTCGAGAATAGCCGGCGCAACCAGTCGGTCGTAGAGCACCACGTCGGCCTGCTGCATCAAGCGCAGGGCGCGGAAGGTCAGCAGATCGGGATCGCCCGGACCGGCGCCGACCAGATAGACCTCACCGCGAGACTCGGCCTGCGGTGCTTCCAGCTTGTCCGCCAGCAGGCATTCGGCTTCGCTCGGCTGGCCGGCGAGCATGCGCTCGGCGACCGGGCCCTGGAACACCTCTTCCCAGAACTTGCGGCGCTGCTGCAGGTCCGGCAGGCGTTGTTTCACGCGCTCGCGGAAGCGGCTGGCGAGGCCGGCCAACTGGCCATAGGTCGCGGGAATCCAGGTTTCCAGCTTGGCGCGCAGCAGGCGAGCCAGCACCGGCGCATCGCCGCCACTGGAAACCGCCACCACCAGTGGCGATCGGTCGACAATGGCCGGGAAGATCACACTGCACAGGGCCGGCGCATCGACGACATTGACCGGAACGCCACGCTCGTTGGCGTCGCGGGAAACCTGGGCATTGAGCGGCTCATCGTCGGTGGCGGCGATGACCAGAACGCAATCCTGAAGATCACCCTGAGCGTAGGGGCGCAGGAGCAATTCGCCCGCGCCCTCCTCGATCAGCTCACGCAGCTCCGAATGCACTTCCGGAGCCACGACTCGCAGCACTGCGCCGGCGTCGCTCAGCAGACGCGCCTTGCGCAGTGCGACATCACCGCCGCCGACCAGTAGCGCGCGACGTCCGCGCAGGATGTGGAACAGCGGCAGGAAGTCCATCTCAGCCGATGACCTCGATGCCCGCCATGTACGGCTTGAGCGCCTCCGGTACGCGGATCGAACCGTCGGCCTGCTGGTAGTTCTCCAGCACGGCGACCAGCGTGCGGCCCACGGCCAGACCCGAGCCGTTGAGGGTGTGCACCAGCTCCGGCTTGCCGGTTTCCGGGTTGCGGTAGCGCGCCTGCATGCGGCGGGCCTGGAAGTCGCCGCAGTTGGAGCAGGAGGAAATCTCGCGGTACTTGTCCTGGCTCGGCACCCAGACTTCGAGGTCGTAGGTCTTGGCGGCGCCGAAGCCCATGTCGCCGGTGCACAGTGCCAAGGCACGGTATGGCAGCTCCAGGGCCTGGAGGACCTTCTCGGCGTTGCCGACCAGGCTCTCCAGCGCCTCCCAGGACTTGGACGGCTCGACGATCTGCACCATCTCAACCTTGTCGAACTGGTGCTGGCGGATCATGCCGCGGGTGTCGCGGCCCGATGCACCGGCTTCGCTGCGAAAGCAGGGCGTGTGGGCGACGAACTTCAGCGGCAGCTCCTTCGCGTCGAGGATCTGCCCGGCAACGATGTTGGTCAGCGAGACTTCGGCGGTCGGGATCAGGTAAAGGTCGGCTTCGTCTTCGCGCTGGATCTTGAACAGGTCTTCCTCGAACTTCGGCAACTGGCCGGTGCCCTGTAGCGCCGGAGCCTGCACCAGGTAGGGGGTGTAGGCCTCTTCGTAGCCATGCTCGCGGGTGTGTAGGTCGATCATGAACTGCGCCAGGGCGCGATGCAGGCGGGCGATCGGGCCGCGCATCAGGGCGAAGCGGGCACCGGACAGGCGGGCGGCAGTCTCGAAGTCCAGCCAGCCGTGCTGCTCGCCCAGGGCGACGTGGTCCTTGATGTCGAAATCGAAGGTGCGCGGGGTGCCCCAGCGACGGACTTCGACGTTCTCTTCCTCGTCGGCGCCCACCGGCACGGATTCGTGTGGCAGGTTCGGGATGTTCAGCAGCAGGCTGTCCAGCTCGGCCTGGATGGCGTCCAGTTCGCGCTTGCCGGATTCCAGCTCCTCGGCCATGCGATTGACCTCGGCCTTCAGCGGCGCGACGTCTTCGCCGTTCTTCATGGCCAGGCCGATGGCCTTGGAACGCGAGTTGCGCTCGGCCTGCAGGGTCTCGGTGCGGGTCTGCACGGACTTGCGCTGGCTCTCCAGCGCTTCGATGCGCGCCACGTCCAGGGTGAAGCCACGGGTGGCCAGGCGTTCGGCCACTTCCTGCGGCTGGGTACGAACCAGTTTGGAATCGAGCAT

Protein sequences of DBSCAN-SWA_3

>NC_020829|3069715:3077725|3075057_3076443_-|WP_015477453.1|DBSCAN-SWA
MDFLPLFHILRGRRALLVGGGDVALRKARLLSDAGAVLRVVAPEVHSELRELIEEGAGELLLRPYAQGDLQDCVLVIAATDDEPLNAQVSRDANERGVPVNVVDAPALCSVIFPAIVDRSPLVVAVSSGGDAPVLARLLRAKLETWIPATYGQLAGLASRFRERVKQRLPDLQQRRKFWEEVFQGPVAERMLAGQPSEAECLLADKLEAPQAESRGEVYLVGAGPGDPDLLTFRALRLMQQADVVLYDRLVAPAILELCRRDADRLYVGKRRADHAVPQDEINRRLVELAQQGKRVLRLKGGDPFIFGRGGEEIDELAANGISFQVVPGITAASGCAAYAGIPLTHRDYAQSVRFVTGHLKDGSTDLPWNDLVAPGQTLVFYMGLVGLPVICEQLVRHGRSADTPAALIQQGTTVHQRVFTGTLANLPQLVAEHEVHAPTLVIVGEVVQLRDKLAWFEGQR
>NC_020829|3069715:3077725|3073599_3074601_+|WP_015477451.1|DBSCAN-SWA
MGQLIDGRWHDQWYDTSKDGRFQRENAQRRNWITADGQPGPSGEGGFRAEASRYHLYVSLACPWAHRTLIYRQLKGLESLIDVSVVSWLMLENGWTFDKTLGSTGDKLDVLDFLHQRYTRDDAHYTGRVTVPVLWDKHEQRIVSNESAEIIRMFNSAFDGITGNRLDLYPEPLRTQIDELNERIYPAVNNGVYRAGFATTQDAYEEAFKTLFGELDRLDERLGKQRYLTGEYLTEADVRLFTTLIRFDAVYHGHFKCNLRRLADYPNLSGWLHELYQLDGVAGTVDFQHIKNHYYASHRTINPTGVVPLGPQQDFTGPHGREHLPGKGIARKR
>NC_020829|3069715:3077725|3072180_3072516_+|WP_015477449.1|DBSCAN-SWA
MSTLLVNGQSLPLDKDGYLAQLDDWSDAAAEALAHNEGIHLTPEHWEILLLLREFYGEFQLSPANRPLIKYVAQRLGTEKGSSLHLNLLFKGTPAKLAAKLAGLPKPTNCL
>NC_020829|3069715:3077725|3071522_3071882_+|WP_015477447.1|DBSCAN-SWA
MAKSLLIISRQAPWAGPAAREALDIALAGGAFDLPISMLFLDDGVFQLAPGQRPSNLEQKDLQANLQALPLFGVEALYVSQRSLGERGLDAASLTLPAQALDAAALRDLLQTHDQVITI
>NC_020829|3069715:3077725|3071881_3072184_+|WP_015477448.1|DBSCAN-SWA
MATLHLLSHSPFNDGRLASCLHLLGPDDGLLLSGEAVYALRDGTAPCQVLELMPATNGLFALLEDLQARGMDDVPARVIAVDYPGFVELCTRFDKVNAWL
>NC_020829|3069715:3077725|3074713_3075061_-|WP_015477452.1|DBSCAN-SWA
MRTVHGVALGVACALGFVVLPASAASFDCRKAKQADEKAICADRQLSELDVQMATTYRLLRGLFAMGMRGNLGDSQLAWLEQRRACGTDKACLKQRYQERLDALQKVYDGIDKPI
>NC_020829|3069715:3077725|3069715_3070381_-|WP_015477445.1|DBSCAN-SWA
MQERQYLDSTAVEQKEVSGVLRNTYGLLALTLAFSGLVAFASQQMRLPYPSIFVVLLGFYGLFFLTVKLRNSAWGLLSTFALTGFMGYTLGPILNLYLGMANGASVISSAFFMTALVFFGLSAYVLTTRKDMSFLSGFITAGFFVLMGAVLVSLFFQISGLQLAISAGFVLFSSAMILFQTSAIIHGGERNYIMATISLYVSIYNLFLSLLQIFGIMGSDD
>NC_020829|3069715:3077725|3071130_3071523_+|WP_015477446.1|DBSCAN-SWA
MKFVIALFSPPHSPAARRALRFAEAALAGGHEITRLFFYQDGVYSASANAVAGQDELDVAAAWSRFVADNQLDGVVCIAAALRRGVLNNEEANRYSRPAANLQAPWDLSGLGQLHEAAQLADRLVCFGGD
>NC_020829|3069715:3077725|3072512_3073511_+|WP_015477450.1|DBSCAN-SWA
MTASPLVLQTPEEHPFAQFVRILGKGKRGARGLTREEAREALGMILDDKVEEAQLGAFLMLLRHKEESAEELAGFTEAVRSRLQTPKIAVDLDWPSYAGKKRHLPWFLLAAKCLGGSGTRILLHGGGAHTAGRLYTEQLLEQLGLPLCRDWSSVSEALDAKGIAFAPLADWMPRMQRMIDLRNTLGLRSPMHSAVRLINPLGATCVLQSIFHPGYQAVHREGSRLLGDYAIVIKGEGGEIEVNPDATSHLYGCRAGEAWDEEWPALSPLRHVKPETLDPQHLAAVWRGDEEDAYGELAVRATMALVLRAMGLQRDEAFAEADKRWAARDRSI
>NC_020829|3069715:3077725|3076444_3077725_-|WP_015477454.1|tRNA|DBSCAN-SWA
MLDSKLVRTQPQEVAERLATRGFTLDVARIEALESQRKSVQTRTETLQAERNSRSKAIGLAMKNGEDVAPLKAEVNRMAEELESGKRELDAIQAELDSLLLNIPNLPHESVPVGADEEENVEVRRWGTPRTFDFDIKDHVALGEQHGWLDFETAARLSGARFALMRGPIARLHRALAQFMIDLHTREHGYEEAYTPYLVQAPALQGTGQLPKFEEDLFKIQREDEADLYLIPTAEVSLTNIVAGQILDAKELPLKFVAHTPCFRSEAGASGRDTRGMIRQHQFDKVEMVQIVEPSKSWEALESLVGNAEKVLQALELPYRALALCTGDMGFGAAKTYDLEVWVPSQDKYREISSCSNCGDFQARRMQARYRNPETGKPELVHTLNGSGLAVGRTLVAVLENYQQADGSIRVPEALKPYMAGIEVIG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015477445.1|3069715_3070381_-	Bax inhibitor-1/YccA family protein	A0A2H4JFM9	uncultured_Caudovirales_phage	1.2e-87	80.3
WP_015477446.1|3071130_3071523_+	sulfurtransferase complex subunit TusD	A0A2H4JA39	uncultured_Caudovirales_phage	4.8e-49	73.6
WP_015477447.1|3071522_3071882_+	sulfurtransferase complex subunit TusC	A0A2H4J8C0	uncultured_Caudovirales_phage	8.3e-32	59.2
WP_015477448.1|3071881_3072184_+	sulfurtransferase complex subunit TusB	A0A2H4JG28	uncultured_Caudovirales_phage	1.1e-24	59.0
WP_015477449.1|3072180_3072516_+	TusE/DsrC/DsvC family sulfur relay protein	A0A2H4J8B6	uncultured_Caudovirales_phage	2.3e-39	73.0
WP_015477450.1|3072512_3073511_+	glycosyl transferase family protein	A0A2H4JBY5	uncultured_Caudovirales_phage	5.7e-139	70.7
WP_015477451.1|3073599_3074601_+	glutathione S-transferase family protein	NA	NA	NA	NA
WP_015477452.1|3074713_3075061_-	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_015477453.1|3075057_3076443_-	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_015477454.1|3076444_3077725_-|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	9.7e-99	45.4