CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_020559	Mycobacterium tuberculosis str. Erdman = ATCC 35801 chromosome 1, complete sequence	17 crisprs	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	10	23	2	1

1. NC_020559

CRISPR-Cas detection and classification

Crispr_ID: NC_020559_1

• CRISPR_ID: NC_020559_1
• CRISPR_location: 334145-334256
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_020559_1

Consensus_repeat	Method
CCGCCG---------TTGCCGCCGTTGCCGATCA	PILER-CR

spacers of NC_020559_1

>1.1|334171|21|NC_020559|PILER-CR
TGCACGCCGTTACCGCCCGCT
>1.2|334218|17|NC_020559|PILER-CR
CGCTGGCGCCGCCGTCA

CRISPR arrays and Neighbor proteins around NC_020559_1

CRISPR arrays

The CRISPR arrays of NC_020559_1

>merge|NC_020559|1|334145-334256|PILER-CR
CGCCGTTGCCGCCGTTGCCGATCTGCACGCCGTTACCGCCCGCTCCGCCGTTGCCGCCGGTGCCGGTCACGCTGGCGCCGCCGTCACCGCCGTTGCCGCCGTTGCCGATCAA

>NC_020559|1|1|334145-334256|PILER-CR
CGCCGTTGCCGCCGTTGCCGATCTGC	ACGCCGTTACCGCCCGCTCCG
CCGTTGCCGCCGGTGCCGGTCACGCT	GGCGCCGCCGTCACCGC
CGTTGCCGCCGTTGCCGATCAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_003401478.1|346014_350007_+|type-VII-secretion-system-ESX-3-FtsK/SpoIIIE-family-ATPase-EccC3	unknown	unknown	gnl|CDD|274858
NC_020559.1|WP_011961607.1|332475_332658_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003401448.1|341377_342286_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|225852
NC_020559.1|WP_003401503.1|351904_352198_+|type-VII-secretion-system-protein-EsxG	unknown	unknown	gnl|CDD|274862
NC_020559.1|WP_015456116.1|336753_339453_-|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_020559.1|WP_003401399.1|329737_330319_+|VOC-family-protein	unknown	unknown	gnl|CDD|366361
NC_020559.1|WP_003401514.1|352227_352518_+|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl|CDD|227179
NC_020559.1|WP_003899884.1|323882_325565_+|acyl-CoA-synthetase	unknown	unknown	gnl|CDD|236097
NC_020559.1|WP_003899886.1|330248_330974_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NC_020559.1|WP_003401472.1|344401_346018_+|type-VII-secretion-system-ESX-3-subunit-EccB3	unknown	unknown	gnl|CDD|368288
NC_020559.1|WP_003401406.1|332023_332452_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350245
NC_020559.1|WP_003401397.1|329020_329641_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NC_020559.1|WP_003401488.1|350314_351856_+|type-VII-secretion-system-ESX-3-target-PPE4	unknown	unknown	gnl|CDD|227938
NC_020559.1|WP_003401404.1|331063_331984_+|DUF2236-domain-containing-protein	unknown	unknown	gnl|CDD|226188
NC_020559.1|WP_003401394.1|327890_329024_-|hypothetical-protein	unknown	unknown	gnl|CDD|378820
NC_020559.1|WP_010950374.1|339743_341354_+|PPE-family-protein	unknown	unknown	gnl|CDD|227938
NC_020559.1|WP_003401485.1|350003_350312_+|type-VII-secretion-system-ESX-3-target-PE5	unknown	unknown	gnl|CDD|376422
NC_020559.1|WP_003401386.1|322653_323847_-|DNA-polymerase-domain-containing-protein	unknown	unknown	gnl|CDD|225823
NC_020559.1|WP_003898392.1|342509_344405_+|type-VII-secretion-system-ESX-3-AAA-family-ATPase-EccA3	unknown	unknown	gnl|CDD|188437
NC_020559.1|WP_003401392.1|325581_327777_-|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|173841

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_003401478.1|346014_350007_+|type-VII-secretion-system-ESX-3-FtsK/SpoIIIE-family-ATPase-EccC3	gnl|CDD|274858	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa. This model represents the N-terminal domain or EccCa subunit of the type VII secretion protein EccC as found in the Actinobacteria. Type VII secretion is defined more broadly as including secretion systems for ESAT-6-like proteins in the Firmicutes as well as in the Actinobacteria, but this family does not show close homologs in the Firmicutes. [Protein fate, Protein and peptide secretion and trafficking].	0
NC_020559.1|WP_003401448.1|341377_342286_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|225852	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	1.10201e-94
NC_020559.1|WP_003401503.1|351904_352198_+|type-VII-secretion-system-protein-EsxG	gnl|CDD|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	0.00514324
NC_020559.1|WP_015456116.1|336753_339453_-|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	4.73961e-33
NC_020559.1|WP_003401399.1|329737_330319_+|VOC-family-protein	gnl|CDD|366361	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.	5.1808e-20
NC_020559.1|WP_003401514.1|352227_352518_+|WXG100-family-type-VII-secretion-target	gnl|CDD|227179	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown].	2.85211e-21
NC_020559.1|WP_003899884.1|323882_325565_+|acyl-CoA-synthetase	gnl|CDD|236097	PRK07788, PRK07788, acyl-CoA synthetase; Validated.	0
NC_020559.1|WP_003899886.1|330248_330974_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	7.66172e-07
NC_020559.1|WP_003401472.1|344401_346018_+|type-VII-secretion-system-ESX-3-subunit-EccB3	gnl|CDD|368288	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B. EccB is a family of largely Gram-positive bacterial transmembrane componenets of the type VII secretion system characterized in Mycobacterium tuberculosis, systems ESX1-5. Translocation of virulent peptides through the membranes is thought to be mediated via a complex that includes EccB, EccC, EccD, EccE, and MycP. EccB, EccC, EccD, and EccE form a stable complex in the mycobacterial cell envelope.	0
NC_020559.1|WP_003401406.1|332023_332452_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350245	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC25, VapC29, VapC33, VapC37, and VapC39 toxins. It belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is a PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.23805e-60
NC_020559.1|WP_003401397.1|329020_329641_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	6.87158e-12
NC_020559.1|WP_003401488.1|350314_351856_+|type-VII-secretion-system-ESX-3-target-PPE4	gnl|CDD|227938	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion].	1.09345e-59
NC_020559.1|WP_003401404.1|331063_331984_+|DUF2236-domain-containing-protein	gnl|CDD|226188	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown].	2.89836e-118
NC_020559.1|WP_003401394.1|327890_329024_-|hypothetical-protein	gnl|CDD|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	0.00172554
NC_020559.1|WP_010950374.1|339743_341354_+|PPE-family-protein	gnl|CDD|227938	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion].	1.45056e-73
NC_020559.1|WP_003401485.1|350003_350312_+|type-VII-secretion-system-ESX-3-target-PE5	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	7.41358e-11
NC_020559.1|WP_003401386.1|322653_323847_-|DNA-polymerase-domain-containing-protein	gnl|CDD|225823	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair].	2.78761e-127
NC_020559.1|WP_003898392.1|342509_344405_+|type-VII-secretion-system-ESX-3-AAA-family-ATPase-EccA3	gnl|CDD|188437	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA. This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking].	0
NC_020559.1|WP_003401392.1|325581_327777_-|acyl-CoA-dehydrogenase-family-protein	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	1.76306e-158

Protein sequences

>NC_020559.1|WP_011961607.1|332475_332658_-|hypothetical-protein
MGAVIEDALRRELAAARTGGARPTVPVFDAGTGPRPGIDLTSNTVLSEVLDEGLELNSRK
>NC_020559.1|WP_003401406.1|332023_332452_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MFLIDVNVLLAAHRGDHPNHRTVRPWFDRLLAADDPFTVPNLVWASFLRLTTNRRIFEIPSPRADAFAFVEAVNAQPHHLPTSPGPRHLVLLRKLCDEADASGDLIPDAVLGAIAVEHHCAVVSLDRDFARFASVRHIRPPI
>NC_020559.1|WP_003401404.1|331063_331984_+|DUF2236-domain-containing-protein
MAISLVAHQPIPHVERPMADPPRLQLARRRRSAAGPGGNEDSLMGVALLAGPANVIMELAMPGVGYGVLESRVESGRLDRHPIKRARTTFTYVAVAVAGSDDQKAAFRRAVNKVHAQVYSTPESPVSYHAFDPELQLWVAACLYKGGVDVYRTFVGEMDDEEADHHYRAGMAMGTTLQVPPQMWPPDRAAFDRYWRQSLDRVHIDDVVRDYLYPIVALRIRGIALPGPLRRLSEGIALLITTGFLPQRFRDEMRLPWDATKQRRFDALMAVLRTVNRLMPRFVREFPFNLMLWDLDRRMRRGRPLV
>NC_020559.1|WP_003899886.1|330248_330974_-|TetR/AcrR-family-transcriptional-regulator
MTRSDRPYRGVEAAERLATRRRQSLSAGLDLLGSDQHDIAELTIRTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTAVPAREQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESSALFAMLSGQHAVDTLHAPANDHVKAVAHFAVGGVGQTISAWLAGDVRLDPDQLVDQLAALLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQPPSSARPARRS
>NC_020559.1|WP_003401399.1|329737_330319_+|VOC-family-protein
MIKPHNTNTEFELGGINHVALVCSDMARTVDFYSNILGMPLIKALDLPGGQGQHFFFDAGNGDCVAFFWFADAPDRVPGLSSPVAIPGIGDITSAVSTMNHLAFHVPAERFDAYRQRLKDKGVRVGPVLNHDDSETQVSAVVHPGVYVRSFYFQDPDGITLEFACWTKEFTTSDAQAVPKTAADRRPPVAADR
>NC_020559.1|WP_003401397.1|329020_329641_-|TetR/AcrR-family-transcriptional-regulator
MPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDDQACIQTLANIYYRAIYSKEDSSN
>NC_020559.1|WP_003401394.1|327890_329024_-|hypothetical-protein
MTGRAATPGVIREFVGLPSRTAGRAAAGGHPCQGLYHHSVGRKPKVALIAAHYQIDFSEHYLAEYMAIRGIGFLGWNTRFRGFESSFLLDHALVDIGVGVRWLREVQGVETVVLLGNSGGGSLMAAYQSQAVDPNVTPLDGMRPAAGVTELPAADAYVAAAAHPGRPDVLTAWMDAAVIDENDPVATDPELDLFDERNGPPYSPEFISRYRSAQVKRNHTITDWAESELKRVRAAGFSDRPFSVMRTWADPRMVDPSIEPTKRRPNQCYAGTPVKANRSAHGIAAACTLRGWLGMWSLRVAQTRAAPHLARITCPALVLNAEADTGIFPSDAQQIYDGLASSDKTQVSIDTDHYFTTPGARSEQADTIAKWIAKRWR
>NC_020559.1|WP_003401392.1|325581_327777_-|acyl-CoA-dehydrogenase-family-protein
MSIAITPEHYELADSVRSLVARVAPSEVLHAALESPVENPPPYWQAAAEQGLQGVHLAESVGGQGFGILELAVVLAEFGYGAVPGPFVPSAIASALIAAHDPQAKVLAELATGAAIAAYALDSGLTATRHGDVLVIRGEVRAVPAAAQASVLVLPVAIESRDEWVVLRNDQLEIEAVKSLDPLRPIAHVRANAVDVSDDALLSNLTMTTAHALMSTLLSAEAVGVARWATDTASAYAKIREQFGRPIGQFQAIKHKCAEMIADTERATAAVWDAARALDDAGESSSDVEFAAAVAATLAPATAQRCTQDCIQVHGGIGFTWEHDTNVYYRRALMLAACFGRGSEYPQRVVDTATTAGMRPVDIDLDPSTEKLRAQIRAEVAALKAMPREPRTVAIAEGGWVLPYLPKPWGRAASPVEQIIIAQEFTAGRVKRPQIAIATWIVPSIVAFGTDNQKQRLLPPTFRGDIFWCQLFSEPGAGSDLASLATKATRVDGGWRITGQKIWTTGAQYSQWGALLARTDPSAPKHNGITYFLLDMKSEGVQVKPLRELTGKEFFNTVYLDDVFVPDELVLGEVNRGWEVSRNTLTAERVSIGGSDSTFLPTLGEFVDFVRDYRFEGQFDQVARHRAGQLIAEGHATKLLNLRSTLLTLAGGDPMAPAAISKLLSMRTGQGYAEFAVSSFGTDAVIGDTERLPGKWGEYLLASRATTIYGGTSEVQLNIIAERLLGLPRDP
>NC_020559.1|WP_003899884.1|323882_325565_+|acyl-CoA-synthetase
MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELRKL
>NC_020559.1|WP_003401386.1|322653_323847_-|DNA-polymerase-domain-containing-protein
MSRMAAPVSLDVHGRQVIVTHPGRVVFPAHNDRKGYTKFDLVRYYLAVAEGAMRGVAGRPMILKRFVKGISAEAVFQKRAPANRPDWVDVAELHYASGRSAAEAVIHDAAGLAWVINLGCVDLNPHPVLAGDLDHPDELRVDLDPMPGVAWQRVVEVALVVREVLEDYGLTAWPKTSGSRGFHVYARIAPCWSFPQVRLAAQTVAREVERRLPDAATSRWWKEEREGVFVDFNQNAKDRTVASAYSVRATPDARVSTPLHWEEVPGCDPAVFTMATVPSRLADIGDPWAGMDDAVGRLDRLLMLAEELGPPQKAQSAKPLIEIARAKTRAEAMAALDIWRDRYPGAAALLRPADVLVDGMRGPSSIWYRIRINLQHVPADQRPPQEELIADYSPWPR
>NC_020559.1|WP_015456116.1|336753_339453_-|PE-family-protein
MSFVIAAPEVIAAAATDLASLESSIAAANAAAAANTTALLAAGADEVSTAVAALFGAHGQAYQALSAQAQAFHAQFVQALTSGGGAYAAAEAAAVSPLLDPINEFFLANTGRPLIGNGANGAPGTGANGGDGGWLIGNGGAGGSGAAGVNGGAGGNGGAGGLIGNGGAGGAGGVASSGIGGSGGAGGNAMLFGAGGAGGAGGGVVALTGGAGGAGGAGGNAGLLFGAAGVGGPGGFTNGSALGGAGGAGGAGGLFATGGVSGSGGAGSSGGAGGAGGAGGLFGAGGTGGHGGFADSSFGGVGGAGGAGGLFGAGGEGGSGGHSLVAGGDGGAGGNAGMLALGAAGGAGGIGGDGGTLTAGGMSGAGGAGGNAGLLFGSGGSGGAGGFGFADGGQGGPGGNAGTVFGSGGAGGNGGVGQGFAGGIGGAGGTPGLIGNGGNGGNGGASAVTGGNGGIGGTGVLIGNGGNGGSGGIGAGKAGVGGVSGLLLGLDGFNAPASTSPLHTLQQNVLNVVNEPFQTLTGRPLIGNGANGTPGTGADGGAGGWLFGNGGNGGSGATGTNGGDGGDGGAGGIFFGTGGTGGAGGVGTTGTGGDGGAGGAAFLMGSGGNGGSGGAGLTAGGDGGDGGNAGSFFGAAGTGGAGASTKAGGTGGTGGNGGLFANGGAGGSGGLGGDAGTGGAGGNGGLFGAGGTGGAGGSLGPGAGGAGGNGGLFGAGGTGGSGGHGTPAAVPGGAGGAGGNAGLFSLGASGGAGGSGGSSLTDGGGIGGVGGAGGLLFGYGGAGGAGGYSNIGAGGAGGAGGNAGMLSGSGGSGGTGGASGAAKGGVGGNGGTAGVFGNGGDGGAGGFGAGTGGNGGVGGNAVLIGNGGNGGNGGKAGGTPGAGGTSGLLIGENGLNGLP
>NC_020559.1|WP_010950374.1|339743_341354_+|PPE-family-protein
MTLWMASPPEVHSALLSSGPGPGSVLSAAGVWSSLSAEYAAVADELIGLLGAVQTGAWQGPSAAAYVAAHAPYLAWLMRASETSAEAAARHETVAAAYTTAVAAMPTLVELAANHTLHGVLVATNFFGINTIPIALNEADYARMWTQAASTMATYQAVAEAAVASAPQTTPAPPILAAEAADDDHDHDHDHGGEPTPLDYLVAEILRIISGGRLIWDPAEGTMNGIPFEDYTDAAQPIWWVVRAIEFSKDFETFVQELFVNPVEAFQFYFELLLFDYPTHIVQIVEALSQSPQLLAVALGSVISNLGAVTGFAGLSGLAGMQPAAIPALAPVAAAPPTLPAVAMAPTMAAPGAAVASAAAPASAPAASTVASATPAPPPAPGAAGFGYPYAIAPPGIGFGSGMSASASAQRKAPQPDSAAAAAAAAAVRDQARARRRRRVTRRGYGDEFMDMNIDVDPDWGPPPGEDPVTSTVASDRGAGHLGFAGTARREAVADAAGMTTLAGDDFGDGPTTPMVPGSWDPDRDAPGSAEPGDRG
>NC_020559.1|WP_003401448.1|341377_342286_+|class-I-SAM-dependent-methyltransferase
MRTEGDSWDITTSVGSTALFVATARALEAQKSDPLVVDPYAEAFCRAVGGSWADVLDGKLPDHKLKSTDFGEHFVNFQGARTKYFDEYFRRAAAAGARQVVILAAGLDSRAYRLPWPDGTTVFELDRPQVLDFKREVLASHGAQPRALRREIAVDLRDDWPQALRDSGFDAAAPSAWIAEGLLIYLPATAQERLFTGIDALAGRRSHVAVEDGAPMGPDEYAAKVEEERAAIAEGAEEHPFFQLVYNERCAPAAEWFGERGWTAVATLLNDYLEAVGRPVPGPESEAGPMFARNTLVSAARV
>NC_020559.1|WP_003898392.1|342509_344405_+|type-VII-secretion-system-ESX-3-AAA-family-ATPase-EccA3
MAGVGEGDSGGVERDDIGMVAASPVASRVNGKVDADVVGRFATCCRALGIAVYQRKRPPDLAAARSGFAALTRVAHDQCDAWTGLAAAGDQSIGVLEAASRTATTAGVLQRQVELADNALGFLYDTGLYLRFRATGPDDFHLAYAAALASTGGPEEFAKANHVVSGITERRAGWRAARWLAVVINYRAERWSDVVKLLTPMVNDPDLDEAFSHAAKITLGTALARLGMFAPALSYLEEPDGPVAVAAVDGALAKALVLRAHVDEESASEVLQDLYAAHPENEQVEQALSDTSFGIVTTTAGRIEARTDPWDPATEPGAEDFVDPAAHERKAALLHEAELQLAEFIGLDEVKRQVSRLKSSVAMELVRKQRGLTVAQRTHHLVFAGPPGTGKTTIARVVAKIYCGLGLLKRENIREVHRADLIGQHIGETEAKTNAIIDSALDGVLFLDEAYALVATGAKNDFGLVAIDTLLARMENDRDRLVVIIAGYRADLDKFLDTNEGLRSRFTRNIDFPSYTSHELVEIAHKMAEQRDSVFEQSALHDLEALFAKLAAESTPDTNGISRRSLDIAGNGRFVRNIVERSEEEREFRLDHSEHAGSGEFSDEELMTITADDVGRSVEPLLRGLGLSVRA
>NC_020559.1|WP_003401472.1|344401_346018_+|type-VII-secretion-system-ESX-3-subunit-EccB3
MTNQQHDHDFDHDRRSFASRTPVNNNPDKVVYRRGFVTRHQVTGWRFVMRRIAAGIALHDTRMLVDPLRTQSRAVLMGVLIVITGLIGSFVFSLIRPNGQAGSNAVLADRSTAALYVRVGEQLHPVLNLTSARLIVGRPVSPTTVKSTELDQFPRGNLIGIPGAPERMVQNTSTDANWTVCDGLNAPSRGGADGVGVTVIAGPLEDTGARAAALGPGQAVLVDSGAGTWLLWDGKRSPIDLADHAVTSGLGLGADVPAPRIIASGLFNAIPEAPPLTAPIIPDAGNPASFGVPAPIGAVVSSYALKDSGKTISDTVQYYAVLPDGLQQISPVLAAILRNNNSYGLQQPPRLGADEVAKLPVSRVLDTRRYPSEPVSLVDVTRDPVTCAYWSKPVGAATSSLTLLAGSALPVPDAVHTVELVGAGNGGVATRVALAAGTGYFTQTVGGGPDAPGAGSLFWVSDTGVRYGIDNEPQGVAGGGKAVEALGLNPPPVPIPWSVLSLFVPGPTLSRADALLAHDTLVPDSRPARPVSAEGGYR
>NC_020559.1|WP_003401478.1|346014_350007_+|type-VII-secretion-system-ESX-3-FtsK/SpoIIIE-family-ATPase-EccC3
MSRLIFEARRRLAPPSSHQGTIIIEAPPELPRVIPPSLLRRALPYLIGILIVGMIVALVATGMRVISPQTLFFPFVLLLAATALYRGNDKKMRTEEVDAERADYLRYLSVVRDNIRAQAAEQRASALWSHPDPTALASVPGSRRQWERDPHDPDFLVLRAGRHTVPLATTLRVNDTADEIDLEPVSHSALRSLLDTQRSIGDVPTGIDLTKVSRITVLGERAQVRAVLRAWIAQAVTWHDPTVLGVALAARDLEGRDWNWLKWLPHVDIPGRLDALGPARNLSTDPDELIALLGPVLADRPAFTGQPTDALRHLLIVVDDPDYDLGASPLAVGRAGVTVVHCSASAPHREQYSDPEKPILRVAHGAIERWQTGGWQPYIDAADQFSADEAAHLARRLSRWDSNPTHAGLRSAATRGASFTTLLGIEDASRLDVPALWAPRRRDEELRVPIGVTGTGEPLMFDLKDEAEGGMGPHGLMIGMTGSGKSQTLMSILLSLLTTHSAERLIVIYADFKGEAGADSFRDFPQVVAVISNMAEKKSLADRFADTLRGEVARREMLLREAGRKVQGSAFNSVLEYENAIAAGHSLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSFRIHILFASQTLDVGKIKDIDKNTAYRIGLKVASPSVSRQIIGVEDAYHIESGKEHKGVGFLVPAPGATPIRFRSTYVDGIYEPPQTAKAVVVQSVPEPKLFTAAAVEPDPGTVIADTDEQEPADPPRKLIATIGEQLARYGPRAPQLWLPPLDETIPLSAALARAGVGPRQWRWPLGEIDRPFEMRRDPLVFDARSSAGNMVIHGGPKSGKSTALQTFILSAASLHSPHEVSFYCLDYGGGQLRALQDLAHVGSVASALEPERIRRTFGELEQLLLSRQQREVFRDRGANGSTPDDGFGEVFLVIDNLYGFGRDNTDQFNTRNPLLARVTELVNVGLAYGIHVIITTPSWLEVPLAMRDGLGLRLELRLHDARDSNVRVVGALRRPADAVPHDQPGRGLTMAAEHFLFAAPELDAQTNPVAAINARYPGMAAPPVRLLPTNLAPHAVGELYRGPDQLVIGQREEDLAPVILDLAANPLLMVFGDARSGKTTLLRHIIRTVREHSTADRVAFTVLDRRLHLVDEPLFPDNEYTANIDRIIPAMLGLANLIEARRPPAGMSAAELSRWTFAGHTHYLIIDDVDQVPDSPAMTGPYIGQRPWTPLIGLLAQAGDLGLRVIVTGRATGSAHLLMTSPLLRRFNDLQATTLMLAGNPADSGKIRGERFARLPAGRAILLTDSDSPTYVQLINPLVDAAAVSGETQQKGSQS
>NC_020559.1|WP_003401485.1|350003_350312_+|type-VII-secretion-system-ESX-3-target-PE5
MTLRVVPEGLAAASAAVEALTARLAAAHASAAPVITAVVPPAADPVSLQTAAGFSAQGVEHAVVTAEGVEELGRAGVGVGESGASYLAGDAAAAATYGVVGG
>NC_020559.1|WP_003401488.1|350314_351856_+|type-VII-secretion-system-ESX-3-target-PPE4
MAAPIWMASPPEVHSALLSNGPGPGSLVAAATAWSQLSAEYASTAAELSGLLGAVPGWAWQGPSAEWYVAAHLPYVAWLTQASADAAGAAAQHEAAAAAYTTALAAMPTLAELAANHVIHTVLVATNFFGINTIPITLNEADYVRMWLQAAAVMGLYQAASGAALASAPRTVPAPTVMNPGGGAASTVGAVNPWQWLLALLQQLWNAYTGFYGWMLQLIWQFLQDPIGNSIKIIIAFLTNPIQALITYGPLLFALGYQIFFNLVGWPTWGMILSSPFLLPAGLGLGLAAIAFLPIVLAPAVIPPASTPLAAAAVAAGSVWPAVSMAVTGAGTAGAATPAAGAAPSAGAAPAPAAPATASFAYAVGGSGDWGPSLGPTVGGRGGIKAPAATVPAAAAAAATRGQSRARRRRRSELRDYGDEFLDMDSDSGFGPSTGDHGAQASERGAGTLGFAGTATKERRVRAVGLTALAGDEFGNGPRMPMVPGTWEQGSNEPEAPDGSGRGGGDGLPHDSK
>NC_020559.1|WP_003401503.1|351904_352198_+|type-VII-secretion-system-protein-EsxG
MSLLDAHIPQLVASQSAFAAKAGLMRHTIGQAEQAAMSAQAFHQGESSAAFQAAHARFVAAAAKVNTLLDVAQANLGEAAGTYVAADAAAASTYTGF
>NC_020559.1|WP_003401514.1|352227_352518_+|WXG100-family-type-VII-secretion-target
MSQIMYNYPAMLGHAGDMAGYAGTLQSLGAEIAVEQAALQSAWQGDTGITYQAWQAQWNQAMEDLVRAYHAMSSTHEANTMAMMARDTAEAAKWGG

Crispr_ID: NC_020559_2

• CRISPR_ID: NC_020559_2
• CRISPR_location: 366833-367531
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 10 spacers

Consensus repeat of NC_020559_2

Consensus_repeat	Method
TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	CRISPRCasFinder

spacers of NC_020559_2

>2.1|366866|27|NC_020559|CRISPRCasFinder
AACGCACCGGTGTCCACATCGCCCGTG
>2.2|366926|27|NC_020559|CRISPRCasFinder
AGGTAGCCCGTGTTGCCACTGCCCGGG
>2.3|366986|42|NC_020559|CRISPRCasFinder
AAGCTGCCGGTGTTGAGGTCCCCGGGGTTGAACACGCCCGTG
>2.4|367061|27|NC_020559|CRISPRCasFinder
AAGCCGCCCGAGTTCGCGAGACCGAAG
>2.5|367121|42|NC_020559|CRISPRCasFinder
CCGGTGCCCGAGTTGAAGAACCCGATGTTTCCGCTGCCGGAG
>2.6|367196|33|NC_020559|CRISPRCasFinder
AGGCTGCCGATCCCGATCTGGCCGTTGCCGGTG
>2.7|367262|27|NC_020559|CRISPRCasFinder
GCGAAGCCGATGTTGTAGCTGCCGGTG
>2.8|367322|57|NC_020559|CRISPRCasFinder
GCGAAGCCGATGTTGTAGCTGCCGGCGTTGCCAAAGCCCAGGTTGTCGTCGCCCAGA
>2.9|367412|27|NC_020559|CRISPRCasFinder
GCCAAGCCGATATCGAAGATCCCGGTG
>2.10|367472|27|NC_020559|CRISPRCasFinder
ACCCCGCCGAAGTTGAGGTCGCCGAGG

CRISPR arrays and Neighbor proteins around NC_020559_2

CRISPR arrays

The CRISPR arrays of NC_020559_2

>merge|NC_020559|2|366833-367531|CRISPRCasFinder
ACCAAGAAGCCGTTGCTGTAGCTGCCGGTAATGAACGCACCGGTGTCCACATCGCCCGTGTTCGCCACGCCCGTGTTGTAGTCACCGGTGTTGAGGTAGCCCGTGTTGCCACTGCCCGGGTTGAAGCCGCCGGTGTTGAAGCTGCCCGGGTTGAAGCTGCCGGTGTTGAGGTCCCCGGGGTTGAACACGCCCGTGTTGGTGCTGCCCGCGTTGCCGATGCCGGTGTTGAAGCCGCCCGAGTTCGCGAGACCGAAGTTGCCGGTGCCGGTGTTAAAGATGCCGACGTTGCCGGTGCCCGAGTTGAAGAACCCGATGTTTCCGCTGCCGGAGTTGAACAGCCCGATGTTGTTGCTGCCCGAGTTGAGGCTGCCGATCCCGATCTGGCCGTTGCCGGTGAGCCCGACGCCGATGTTGTTGTTACCGGTATTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTGGCAAAGCCCAGGTTGTCGCTGCCGAAGTTCGCGAAGCCGATGTTGTAGCTGCCGGCGTTGCCAAAGCCCAGGTTGTCGTCGCCCAGATTTGCCAACCCGATGTTGTAGCTGCCCAGGTTCGCCAAGCCGATATCGAAGATCCCGGTGTTGGCGATGCCGATGTTGTTACCGCCGATGTTGACCCCGCCGAAGTTGAGGTCGCCGAGGTTGCCGATGCCCAGGTTGGAGTCGCCGGTATTA

>NC_020559|2|1|366833-367531|CRISPRCasFinder
ACCAAGAAGCCGTTGCTGTAGCTGCCGGTAATG	AACGCACCGGTGTCCACATCGCCCGTG
TTCGCCACGCCCGTGTTGTAGTCACCGGTGTTG	AGGTAGCCCGTGTTGCCACTGCCCGGG
TTGAAGCCGCCGGTGTTGAAGCTGCCCGGGTTG	AAGCTGCCGGTGTTGAGGTCCCCGGGGTTGAACACGCCCGTG
TTGGTGCTGCCCGCGTTGCCGATGCCGGTGTTG	AAGCCGCCCGAGTTCGCGAGACCGAAG
TTGCCGGTGCCGGTGTTAAAGATGCCGACGTTG	CCGGTGCCCGAGTTGAAGAACCCGATGTTTCCGCTGCCGGAG
TTGAACAGCCCGATGTTGTTGCTGCCCGAGTTG	AGGCTGCCGATCCCGATCTGGCCGTTGCCGGTG
AGCCCGACGCCGATGTTGTTGTTACCGGTATTC	GCGAAGCCGATGTTGTAGCTGCCGGTG
TTGGCAAAGCCCAGGTTGTCGCTGCCGAAGTTC	GCGAAGCCGATGTTGTAGCTGCCGGCGTTGCCAAAGCCCAGGTTGTCGTCGCCCAGA
TTTGCCAACCCGATGTTGTAGCTGCCCAGGTTC	GCCAAGCCGATATCGAAGATCCCGGTG
TTGGCGATGCCGATGTTGTTACCGCCGATGTTG	ACCCCGCCGAAGTTGAGGTCGCCGAGG
TTGCCGATGCCCAGGTTGGAGTCGCCGGTATTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_003401601.1|379025_379517_-|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|379275
NC_020559.1|WP_003401584.1|376282_376954_+|5,6-dimethylbenzimidazole-synthase	unknown	unknown	gnl|CDD|162875
NC_020559.1|WP_003401555.1|363622_363850_+|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	gnl|CDD|279710
NC_020559.1|WP_003401589.1|376941_377424_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003401566.1|364414_364840_+|PIN-domain-nuclease	unknown	unknown	gnl|CDD|350322
NC_020559.1|WP_015456121.1|379540_380770_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_044519818.1|365028_365607_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NC_020559.1|WP_003401538.1|358542_359328_+|trans-aconitate-2-methyltransferase	unknown	unknown	gnl|CDD|184509
NC_020559.1|WP_003900117.1|365603_366512_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|187670
NC_020559.1|WP_003900119.1|380924_382787_+|Hsp70-family-protein	unknown	unknown	gnl|CDD|223520
NC_020559.1|WP_003401613.1|382858_383245_+|hypothetical-protein	unknown	unknown	gnl|CDD|223403
NC_020559.1|WP_003401544.1|360129_361527_-|sulfatase	unknown	unknown	gnl|CDD|293751
NC_020559.1|WP_003401597.1|378299_378956_+|L,D-transpeptidase	unknown	unknown	gnl|CDD|226309
NC_020559.1|WP_003902950.1|383247_383883_-|DUF3060-domain-containing-protein	unknown	unknown	gnl|CDD|371435
NC_020559.1|WP_003401621.1|383970_384855_+|family-16-glycosylhydrolase	unknown	unknown	gnl|CDD|225182
NC_020559.1|WP_003401560.1|363846_364149_+|toxin-antitoxin-system-toxin	unknown	unknown	unknown
NC_020559.1|WP_003401540.1|359316_360120_-|hypothetical-protein	unknown	unknown	gnl|CDD|226848
NC_020559.1|WP_003401563.1|364196_364418_+|type-II-toxin-antitoxin-system-antitoxin-VapB2	unknown	unknown	gnl|CDD|222832
NC_020559.1|WP_003898396.1|357233_358436_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|366166
NC_020559.1|WP_003401594.1|377481_378198_+|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239486

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_003401601.1|379025_379517_-|nuclear-transport-factor-2-family-protein	gnl|CDD|379275	pfam13577, SnoaL_4, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	1.69655e-31
NC_020559.1|WP_003401584.1|376282_376954_+|5,6-dimethylbenzimidazole-synthase	gnl|CDD|162875	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase. A previously published hypothesis that BluB, involved in cobalamin biosynthesis, is EC 1.16.8.1 (cob(II)yrinic acid a,c-diamide reductase) is now contradicted by newer work ascribing a role in 5,6-dimethylbenzimidazole (DMB) biosynthesis. The BluB protein is related to the nitroreductase family (pfam0881). [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	6.73571e-73
NC_020559.1|WP_003401555.1|363622_363850_+|ribbon-helix-helix-protein,-CopG-family	gnl|CDD|279710	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerization and not DNA binding as might have been expected.	0.000113886
NC_020559.1|WP_003401563.1|364196_364418_+|type-II-toxin-antitoxin-system-antitoxin-VapB2	gnl|CDD|222832	PHA01748, PHA01748, hypothetical protein.	0.00852727
NC_020559.1|WP_003401566.1|364414_364840_+|PIN-domain-nuclease	gnl|CDD|350322	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC3 and VapC21 toxins. It belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is a PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.62509e-57
NC_020559.1|WP_044519818.1|365028_365607_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	7.05737e-14
NC_020559.1|WP_003401538.1|358542_359328_+|trans-aconitate-2-methyltransferase	gnl|CDD|184509	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional.	8.03642e-167
NC_020559.1|WP_003900117.1|365603_366512_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|187670	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs. Classical SDR-like subgroup containing LPOR and related proteins. Protochlorophyllide (Pchlide) reductases act in chlorophyll biosynthesis. There are distinct enzymes that catalyze Pchlide reduction in light or dark conditions. Light-dependent reduction is via an NADP-dependent SDR, LPOR. Proteins in this subfamily share the glycine-rich NAD-binding motif of the classical SDRs, have a partial match to the canonical active site tetrad, but lack the typical active site Ser. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.69352e-146
NC_020559.1|WP_003401613.1|382858_383245_+|hypothetical-protein	gnl|CDD|223403	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones].	0.00700797
NC_020559.1|WP_003401544.1|360129_361527_-|sulfatase	gnl|CDD|293751	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase). N-sulfoglucosamine sulfohydrolase (SGSH) belongs to the sulfatase family and catalyses the cleavage of N-linked sulfate groups from the GAGs heparin sulfate and heparin. The active site is characterized by the amino-acid sequence motif C(X)PSR that is highly conserved among most sulfatases. The cysteine residue is post-translationally converted to a formylglycine (FGly) residue, which is crucial for the catalytic process. Loss of function of SGSH results a disease called mucopolysaccharidosis type IIIA (Sanfilippo A syndrome), a fatal childhood-onset neurodegenerative disease with mild facial, visceral and skeletal abnormalities.	5.75322e-137
NC_020559.1|WP_003401597.1|378299_378956_+|L,D-transpeptidase	gnl|CDD|226309	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown].	4.28441e-100
NC_020559.1|WP_003902950.1|383247_383883_-|DUF3060-domain-containing-protein	gnl|CDD|371435	pfam11259, DUF3060, Protein of unknown function (DUF3060). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed.	3.43215e-21
NC_020559.1|WP_003401621.1|383970_384855_+|family-16-glycosylhydrolase	gnl|CDD|225182	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism].	9.91964e-52
NC_020559.1|WP_003900119.1|380924_382787_+|Hsp70-family-protein	gnl|CDD|223520	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones].	3.71262e-67
NC_020559.1|WP_003401540.1|359316_360120_-|hypothetical-protein	gnl|CDD|226848	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown].	2.12891e-123
NC_020559.1|WP_003401594.1|377481_378198_+|phosphatase-PAP2-family-protein	gnl|CDD|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	2.34145e-31
NC_020559.1|WP_003898396.1|357233_358436_-|alpha/beta-fold-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	1.89486e-06

Protein sequences

>NC_020559.1|WP_003900117.1|365603_366512_+|SDR-family-NAD(P)-dependent-oxidoreductase
MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEPNRCSVLEVDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVTGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQVT
>NC_020559.1|WP_044519818.1|365028_365607_+|TetR/AcrR-family-transcriptional-regulator
MLDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET
>NC_020559.1|WP_003401566.1|364414_364840_+|PIN-domain-nuclease
MTDQRWLIDKSALVRLTDSPDMEIWSNRIERGLVHITGVTRLEVGFSAECGEIARREFREPPLSAMPVEYLTPRIEDRALEVQTLLADRGHHRGPSIPDLLIAATAELSGLTVLHVDKDFDAIAALTGQKTERLTHRPPSA
>NC_020559.1|WP_003401563.1|364196_364418_+|type-II-toxin-antitoxin-system-antitoxin-VapB2
MSDVLIRDIPDDVLASLDAIAARLGLSRTEYIRRRLAQDAQTARVTVTAADLRRLRGAVAGLGDPELMRQAWR
>NC_020559.1|WP_003401560.1|363846_364149_+|toxin-antitoxin-system-toxin
MIAPGDIAPRRDSEHELYVAVLSNALHRAADTGRVITCPFIPGRVPEDLLAMVVAVEQPNGTLLPELVQWLHVAALGAPLGNAGVAALREAASVVTALLC
>NC_020559.1|WP_003401555.1|363622_363850_+|ribbon-helix-helix-protein,-CopG-family
MTKEKISVTVDAAVLAAIDADARAAGLNRSEMIEQALRNEHLRVALRDYTAKTVPALDIDAYAQRVYQANRAAGS
>NC_020559.1|WP_003401544.1|360129_361527_-|sulfatase
MTSERATGQRENLLIVHWHDLGRYLGVYHHPDVYSPRLDRLAAEGILFTRAHATAPLCTPSRGSLFTGRYPQSNGLVGLAHHGWEYRTGVQTLPQLLSESGWYSALFGMQHETSYPKRLGFDEFDVSNSYCEYVVAKAQDWLHNRVPALDGQRFLLTAGFFETHRPYPHERYRPADSAAVELPDYLPDTPEVRQDVAEFYGSIATADEAVGRLLDTLADTGLDASTWVVFVTDHGPAFPRAKSTLYDAGTGIALIIRPPTRRAMAPRVYDELFSGVDLVPTLLDLLRLEVPADVEGVSHAPALLAPDTENAAVRDHVYTAKTYHDSFDPIRAIRTKEYSYIENYAPRPLLDLPWDIQESPAGMAVAPLVKAPRPQRELYDLRADPTETNNLLAGDDSTQGVAAIAADLAVRLHDWRQRTADVIPSDFAGSRIAERYTETYLRIHRKTPTGRSAIAADRGIDEHCS
>NC_020559.1|WP_003401540.1|359316_360120_-|hypothetical-protein
MSRAVRPYLVLATQRSGSTLLVESLRATGCAGEPQEFFQYLPSTGMAPQPREWFAGVDDDTILQLLDPLDPGTPDTATPVAWREHVRTSGRTPNGVWGGKLMWNQTALLQQRAAQLPDRSGDGLRAAIRDVIGNEPVFVHVHRPDVVSQAVSFWRAVQTQVWRGHPDPKRDSQAVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPAPMLERQANQRSDEWVDRYRAEAPRLGLPT
>NC_020559.1|WP_003401538.1|358542_359328_+|trans-aconitate-2-methyltransferase
MWDPDVYLAFSGHRNRPFYELVSRVGLERARRVVDLGCGPGHLTRYLARRWPGAVIEALDSSPEMVAAAAERGIDATTGDLRDWKPKPDTDVVVSNAALHWVPEHSDLLVRWVDELAPGSWIAVQIPGNFETPSHAAVRALARREPYAKLMRDIPFRVGAVVQSPAYYAELLMDTGCKVDVWETTYLHQLTGEHPVLDWITGSALVPVRERLSDESWQQFRQELIPLLNDAYPPRADGSTIFPFRRLFMVAEVGGARRSGG
>NC_020559.1|WP_003898396.1|357233_358436_-|alpha/beta-fold-hydrolase
MSGTFTADAIGPPVPIPDVPGADAGAEGLPSRSVLSARQRILVESSAIADVALRTAVASVLSATVTPAVVANALRHVNEGSERSNLNFYAELAAAHDPAKSFPAPTELPKVTSRPASPLTEWVARGTVDNIAFASGFRAINPTMRQRWSALTANNIVHAQHWRHRDGPRPTLCVIHGFMGSSYLLNGLFFSLPWYYRSGYDVLLYTLPFHGQRAEKFSPFSGFGYFTSGLSGFAEAMAQAVYDFRSIVDYLRHIGVDRIALTGISLGGYTSALLASVESRLEAVIPNCPVVMPAKLFDEWFPANKLVKLGLRLTNISRDELIAGLAYHGPLNYRPLLPKDRRMIITGLGDRMAPPEHAVTLWKQWDRCALHWFPGSHLLHVSQLDYLRRMTVFLQGLMFD
>NC_020559.1|WP_003401584.1|376282_376954_+|5,6-dimethylbenzimidazole-synthase
MFSAPERRAVYRVIAERRDMRRFVPGGVVSEDVLARLLHAAHAAPSVGLMQPWRFIRITDETLKRRIHALVDDERLLTAEALGAREEEFLALKVEGILDCAELLVVALCDRRGSYIFGRRTLPQMDLASVSCAIQNLWLAARSEGLGMGWVSLFDPQRLAALLAMPADAEPVAILCLGPVPEFPDRPALELDGWAYARPLAEFVSENRWSYPSALATDHHHGE
>NC_020559.1|WP_003401589.1|376941_377424_-|hypothetical-protein
MAVIVRKWFGLGRLPADLRCQVEAEGLIYLAEYVAVTRRFTGVIPGLRASHSIASYVGALAFTEQRVLGTLSMVPKLAGRVVDARWDGPQAGAATAEISPTGLQLDLDVADVDPKFSGQLALHFKATIGEDVLSRLPRRSLAFDVPAEYVNLAVGVTYSP
>NC_020559.1|WP_003401594.1|377481_378198_+|phosphatase-PAP2-family-protein
MTRPQALLAVSLAFVATAVYAVMWVGHSQDWGWLHSFDWSLLNAAHDIGIKNPAWVRFWDGVSLILGPVVLRPLGLLAAMVALAKRKIRIALLLLACLPLNAIMTIAAKSVAHRPRPATALVSAHSTSFPSGHALEATASVLALLTVLLPMLHSRFTRHIAITVGALCVLTVGVARVALNVHHPTDVVAGWALGYLYFLVCLCVFRPPSIFGAQRASHALSPPVEVSRQPEPEVDTAR
>NC_020559.1|WP_003401597.1|378299_378956_+|L,D-transpeptidase
MSRLLALLCAAVCTGCVAVVLAPVSLAVVNPWFANSVGNATQVVSVVGTGGSTAKMDVYQRTAAGWQPLKTGITTHIGSAGMAPEAKSGYPATPMGVYSLDSAFGTAPNPGGGLPYTQVGPNHWWSGDDNSPTFNSMQVCQKSQCPFSTADSENLQIPQYKHSVVMGVNKAKVPGKGSAFFFHTTDGGPTAGCVAIDDATLVQIIRWLRPGAVIAIAK
>NC_020559.1|WP_003401601.1|379025_379517_-|nuclear-transport-factor-2-family-protein
MCCNGVVTPGDPADIAAIKQLKYRYLRALDTKHWDDFTDTLAEDVTGDYGSSVGTELHFTNRADLVDYLRQALGPGVITEHRVTHPEITVTGDTATGIWYLQDRVIVAEFNFMLIGAAFYHDQYRRTTDGWRISATGYDRTYEATMSLAGLNFNIRPGRALAD
>NC_020559.1|WP_015456121.1|379540_380770_+|hypothetical-protein
MSQSRYAGLSRSELAVLLPELLLIGQLIDRSGMAWCIQAFGRQEMLQIAIEEWAGASPIYTKRMQKALNFEGDDVPTIFKGLQLDIGAPPQFMDFRFTLHDRWHGEFHLDHCGALLDVEPMGDDYVVGMCHTIEDPTFDATAIATNPRAQVRPIHRPPRKPADRHPHCAWTVIIDESYREAEGIPALDAVRETKAATWELDNVDASDDGLVDYSGPLVSDLDFGAFSHSALVRMADEVCLQMHLLNLSFAIAVRKRAKADAQLAISVNTRQLIGVAGLGAERIHRAMALPGGIEGALGVLELHPLLNPAGYVLAETSPDRLVVHNSPAHADGAWISLCTPASVQPLQAIATAVDPHLKVRISGTDTDWTAELIEADAPASELPEVLVAKVSRGSVFQFEPRRSLPLTVK
>NC_020559.1|WP_003900119.1|380924_382787_+|Hsp70-family-protein
MYDPLGLSIGTTNLVAAGNGGPPVTRRAVLTLYPHCAPKIGVPSQNPNLIEPGALMSGFVERIGDAVALVSPDGSVHDPDLLLVEALDAMVLTAGADASSSEIAIAVPAHWKPGAVHALRNGLRTHVGFVRSGMAPRLVSDAIAALTAVNSELGLPHGSVVGLLDFGGSATYVTLVETKSDSRTSDFQPVSATARYQDFSGSQIDQALLLRVIDQFGYGDDVDPASTAAVGQLGQLREQCRAAKERLSTDVATELFAELAGCSSSIEMTREQLEDLIQDPLTGFIYAFDDMLARHNASWADLAAVVTVGGGANIPLVTQRLSFHTRRPVLTASQPGCAAAMGALLLANRGGERDSRTRTSIGLATAAAAGTSVIELPAGDVMVIDHEALTDRELAWSQTDFPSEAPARFEGDSYNEGGPCWSMRLNAVEPPKGPAWRRIRVSQLLIGVSAVVAMTAIGGVALTLTAIERRPSPLPTPIVPGLAPMPPGSVVPSSRAPTPPPPPSTVAPLPSAAPAPTTVAPAPPPPTQVVTTTTAPPVTTTPRPSPTTTTTTAPPSTTTTTEPPVTTTSTIPTIPTTTTTVKMTTEWLHVPFLPVPIPVPIPQNPGAGEPQNPFGSLGSG
>NC_020559.1|WP_003401613.1|382858_383245_+|hypothetical-protein
MGDYGPFGFDPDEFDRVIREGSEGLRDAFERIGRFLSSSGAGTGWSAIFEDLSRRSRPAPETAGEAGDGVWAIYTVDADGGARVEQVYATELDALRANKDNTDPKRKVRFLPYGIAVSVLDDPVDEAQ
>NC_020559.1|WP_003902950.1|383247_383883_-|DUF3060-domain-containing-protein
MNPEDDPEARIRELERPLADVARASELGGSQSGGYTYPPGPPPPPYSYGGPFGGPSPRSSSGNRAWWILAAVVVVGVLVLVGGIAAFSAQRLSQGNFVVLSPTPSVSRAVPTPTAQPATTLPPAGASLSVSGVNVNRTIACNDSIVSVSGMSNTVVITGHCTSLTVSGMRNSVTVDSVDTIEAAGFNNEVTYHSGSPKISNAGGSNSVQQG
>NC_020559.1|WP_003401621.1|383970_384855_+|family-16-glycosylhydrolase
MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAPAAATGGLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFGQYRDSRQNVFLDGNSNLVLRATREGNRYFGGLVHGLWRGGIGTTWEARIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHANPDGTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGIEDLNEPIREWPFNDPGYTVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVRVF

Crispr_ID: NC_020559_3

• CRISPR_ID: NC_020559_3
• CRISPR_location: 692990-693066
• CRISPR_type: TypeV-U4
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020559_3

Consensus_repeat	Method
TGAGGTGCGGCGTGAGCGCGGGT	CRISPRCasFinder

spacers of NC_020559_3

>3.1|693013|31|NC_020559|CRISPRCasFinder
AGCGCGAACGGCAAGCCGAACCGTTGGACCC

CRISPR arrays and Neighbor proteins around NC_020559_3

CRISPR arrays

The CRISPR arrays of NC_020559_3

>merge|NC_020559|3|692990-693066|CRISPRCasFinder
TGAGGTGCGGCGTGAGCGCGGGTAGCGCGAACGGCAAGCCGAACCGTTGGACCCTGAGGTGCGGCGTGAGCGCGGGT

>NC_020559|3|2|692990-693066|CRISPRCasFinder
TGAGGTGCGGCGTGAGCGCGGGT	AGCGCGAACGGCAAGCCGAACCGTTGGACCC
TGAGGTGCGGCGTGAGCGCGGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_003403047.1|678886_679294_+|type-II-toxin-antitoxin-system-toxin-ribonuclease-C26	unknown	unknown	gnl|CDD|350263
NC_020559.1|WP_003900181.1|690022_691468_+|virulence-factor-Mce-family-protein	unknown	unknown	gnl|CDD|273384
NC_020559.1|WP_003900182.1|691464_692901_+|virulence-factor-Mce-family-protein	unknown	unknown	gnl|CDD|273384
NC_020559.1|WP_003898514.1|686891_687779_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223838
NC_020559.1|WP_003900973.1|698868_699375_-|two-component-system-sensor-kinase-HK1	unknown	unknown	gnl|CDD|223715
NC_020559.1|WP_003403148.1|700002_700764_-|two-component-system-response-regulator-TcrA	unknown	unknown	gnl|CDD|223816
NC_020559.1|WP_003403128.1|696632_697868_-|ATP-binding-protein	unknown	unknown	gnl|CDD|224292
NC_020559.1|WP_003403104.1|687784_688999_+|MCE-family-protein	unknown	unknown	gnl|CDD|378749
NC_020559.1|WP_003403095.1|686092_686890_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223838
NC_020559.1|WP_003403144.1|699488_699959_-|two-component-system-sensor-kinase-HK2	unknown	unknown	gnl|CDD|236751
NC_020559.1|WP_003403122.1|695803_696196_-|type-II-toxin-antitoxin-system-toxin-ribonuclease-C4	unknown	unknown	gnl|CDD|350335
NC_020559.1|WP_003403052.1|679353_680040_-|LpqN/LpqT-family-lipoprotein	unknown	unknown	gnl|CDD|378485
NC_020559.1|WP_003403137.1|698118_698532_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350248
NC_020559.1|WP_003403055.1|680193_682827_+|glycoside-hydrolase-family-92-protein	unknown	unknown	gnl|CDD|226067
NC_020559.1|WP_003403065.1|685373_686096_+|FadR-family-transcriptional-regulator-Mce2R	unknown	unknown	gnl|CDD|225097
NC_020559.1|WP_003403125.1|696192_696450_-|type-II-toxin-antitoxin-system-antitoxin-VapB4	unknown	unknown	gnl|CDD|226603
NC_020559.1|WP_003403139.1|698528_698765_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224913
NC_020559.1|WP_003403164.1|700820_701132_+|hypothetical-protein	unknown	unknown	gnl|CDD|377032
NC_020559.1|WP_003403119.1|694201_695752_+|MCE-family-protein	unknown	unknown	gnl|CDD|224380
NC_020559.1|WP_003900178.1|682849_685237_-|flippase-like-domain-containing-protein	unknown	unknown	gnl|CDD|377103

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_003403047.1|678886_679294_+|type-II-toxin-antitoxin-system-toxin-ribonuclease-C26	gnl|CDD|350263	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins. Mycobacterium tuberculosis VapC26 cleaves 23S rRNA in the Sarcin-Ricin Loop, it is inhibited by the cognate VapB26 antitoxin. This subfamily belongs to the VapC (virulence-associated protein C)-like nuclease family of the PIN domain-like superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.4948e-60
NC_020559.1|WP_003900181.1|690022_691468_+|virulence-factor-Mce-family-protein	gnl|CDD|273384	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein. Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis].	1.51384e-92
NC_020559.1|WP_003900182.1|691464_692901_+|virulence-factor-Mce-family-protein	gnl|CDD|273384	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein. Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis].	7.87182e-99
NC_020559.1|WP_003898514.1|686891_687779_+|ABC-transporter-permease	gnl|CDD|223838	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	1.27272e-83
NC_020559.1|WP_003900973.1|698868_699375_-|two-component-system-sensor-kinase-HK1	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.10494e-27
NC_020559.1|WP_003403148.1|700002_700764_-|two-component-system-response-regulator-TcrA	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.00442e-84
NC_020559.1|WP_003403128.1|696632_697868_-|ATP-binding-protein	gnl|CDD|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	1.27416e-77
NC_020559.1|WP_003403104.1|687784_688999_+|MCE-family-protein	gnl|CDD|378749	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative. Mce4_CUP1 is a family of putative Mce4 transporters of cholesterol. The domain is found associated with pfam02470. The full TCDB classification for this family in conjunction with PF02470 is TC:3.A.1.27.4.	1.49168e-114
NC_020559.1|WP_003403095.1|686092_686890_+|ABC-transporter-permease	gnl|CDD|223838	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	9.02403e-82
NC_020559.1|WP_003403144.1|699488_699959_-|two-component-system-sensor-kinase-HK2	gnl|CDD|236751	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB.	1.39186e-13
NC_020559.1|WP_003403122.1|695803_696196_-|type-II-toxin-antitoxin-system-toxin-ribonuclease-C4	gnl|CDD|350335	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 toxin of the VapBC toxin/antitoxin (TA) system. This family belongs to the PIN_VapC4-5_FitB-like subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. M. tuberculosis VapC4 interacts with, and cleaves tRNA44Cys-GCA. M. tuberculosis VapC5 has endonucleolytic activity with RNA, this activity is low with dsRNA, and no activity has been demonstrated on dsDNA. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	5.73431e-57
NC_020559.1|WP_003403052.1|679353_680040_-|LpqN/LpqT-family-lipoprotein	gnl|CDD|378485	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN. This family is conserved in Mycobacteriaceae and is likely to be a lipoprotein.	5.50369e-72
NC_020559.1|WP_003403137.1|698118_698532_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350248	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins. This subfamily includes Mycobacterium tuberculosis VapC27 and VapC40. It belongs to the VapC (virulence-associated protein C)-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	9.76945e-42
NC_020559.1|WP_003403055.1|680193_682827_+|glycoside-hydrolase-family-92-protein	gnl|CDD|226067	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism].	0
NC_020559.1|WP_003403065.1|685373_686096_+|FadR-family-transcriptional-regulator-Mce2R	gnl|CDD|225097	COG2186, FadR, Transcriptional regulators [Transcription].	4.76819e-52
NC_020559.1|WP_003403125.1|696192_696450_-|type-II-toxin-antitoxin-system-antitoxin-VapB4	gnl|CDD|226603	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning].	2.38527e-16
NC_020559.1|WP_003403139.1|698528_698765_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl|CDD|224913	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription].	1.50922e-07
NC_020559.1|WP_003403164.1|700820_701132_+|hypothetical-protein	gnl|CDD|377032	pfam03413, PepSY, Peptidase propeptide and YPEB domain. This region is likely to have an protease inhibitory function (personal obs:C Yeats). This model is likely to miss some members of this family as the separation from signal to noise is not clear. The name is derived from Peptidase & Bacillus subtilis YPEB.	0.00241752
NC_020559.1|WP_003403119.1|694201_695752_+|MCE-family-protein	gnl|CDD|224380	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism].	2.75938e-80
NC_020559.1|WP_003900178.1|682849_685237_-|flippase-like-domain-containing-protein	gnl|CDD|377103	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region. LPG_synthase_TM is the N-terminal region of this family of bacterial phosphatidylglycerol lysyltransferases. The function of the family is to add lysyl groups to membrane lipids, and this region is the transmembrane domain of 7xTMs. In order to counteract attack by membrane-damaging external cationic antimicrobial molecules - from host immune systems, bacteriocins, defencins, etc - bacteria modify their anionic membrane phosphatidylglycerol with positively-charged L-lysine; this results in repulsion of the foreign cationic peptides.	2.17737e-22

Protein sequences

>NC_020559.1|WP_003900182.1|691464_692901_+|virulence-factor-Mce-family-protein
MSTIFDIRSLRLPKLSAKVVVVGGLVVVLAVVAAAAGARLYRKLTTTTVVAYFSEALALYPGDKVQIMGVRVGSIDKIEPAGDKMRVTLHYSNKYQVPATATASILNPSLVASRTIQLSPPYTGGPVLQDGAVIPIERTQVPVEWDQLRDSINGILRQLGPTERQPKGPFGDLIESAADNLAGKGRQLNETLNSLSQALTALNEGRGDFVAITRSLALFVSALYQNDQQFVALNENLAEFTDWFTKSDHDLADTVERIDDVLGTVRKFVSDNRSVLAADVNNLADATTTLVQPEPRDGLETALHVLPTYASNFNNLYYPLHSSLVGQFVFPNFANPIQLICSAIQAGSRLGYQESAELCAQYLAPVLDALKFNYLPFGSNPFSSAATLPKEVAYSEERLRPPPGYKDTTVPGIFSRDTPFSHGNHEPGWVVAPGMQGMQVQPFTANMLTPESLAELLGGPDIAPPAAGNQLARTAECV
>NC_020559.1|WP_003900181.1|690022_691468_+|virulence-factor-Mce-family-protein
MRTLTEFNRGRVGMMGAVVTVLVVGVAQSFTSVPMLFATPTYYAQFADTGGINTGDKVEIAGVNVGLVRSLAIRGNRVLIGFSLPGKTIGMQSRAAIRTDTILGRKNLEIEPRGSEPLKPNGFLPLAQTTTPYQIYDAFVDVTKAATGWDIDAVKRSLNVLSETFDQTAPHLSAALEGVKAFSDTVGRRGEQIEQLLANANRIARVLGDRSEQVNGLLVNAKTLLAAFKQRSQALRILLTNVSEASAQVSGLITDNPNLNHVLAQLRTVSEELVKRKNELADVAVLLGRYTAALTEAVGSGPFFKAMVVNLLPYQILQPWVDAAFKKRGIDPENFWRSAGLPEFRWPDPNGTRFPNGAPPAAPPVREGTPKHPGPAVPPGTPCSYTPAAGALPRPDTPLPCAGATVGPFGGPDFPAPLDVQPSPPNPDGPPPTPGILSAGRPGEPAPAVPGIPMPLPPNAPPGARTQPLEPFPDGTGGSNQ
>NC_020559.1|WP_003403104.1|687784_688999_+|MCE-family-protein
MPTLVTRKNRRAWLYVEGVVLLLVGALVLVLVYKQFRGEFTPKTELTMVASRAGLVMEAGSKVTYNGVEIGRVGSISEIERDGRPAAKLVLDVNPRYISLIPVNVVADIEAATLFGNKYVALSAPKIPQQQRISSHDVIDVGSVTTEFNTLFETITSIAEKVDPIELNATLSAVAQALDGLGGKFGESIVNGNQILAQLNPRLPQLGYDVRRLADLGEVYVDASPDLWSFLQNALTTARTLTSQQRDLDAALLAATGAGNTGEDVFARGGPYLARAAADLVPTATLLDTYSPELFCMIRNFHDAAPKVADAVGGNGYSLAAAGTILGAPNPYVYPDNLPRVNAHGGPGGRPGCWQTITRELWPAPYLVMDTGASLAPYNHVELGQPMFTEYVWGRQYGENTINP
>NC_020559.1|WP_003898514.1|686891_687779_+|ABC-transporter-permease
MVESSTASAAAVLRARYPRTAASLDRYGGGTARRLERTGTFARFTRISVVQIGWALRRYRRETLRLVAEIGMGTGAMAVVGGTVAIIGFVTLSGGSLIAIQGFASLGNIGVEAFTGFFAALANTRVAAPIVSGVALAATVGAGATAQLGAMRISEEIDALEVMGIKSISFLVSTRILGGLVVIMPLYALALDMAFTSGQVVTTVFYGQSNGTYEHYFRTFLRPEDVGWSVVEVVIIAVVVMIIHCYYGYTASGGPVGVGQAVGRSMRFSLVSVVVVVLLAELALYGVDPNFNLTV
>NC_020559.1|WP_003403095.1|686092_686890_+|ABC-transporter-permease
MTTHAVIITYLRDQTQPAVDAIGGFYRTCVLTGKALVRRPFHWREAIEQGWFITSVSLLPTLAVSIPLTVLIIFTLNILLAEFGAADISGAGAALGAVTQLGPLTTVLVIAGAGATAICADLGARTIREEIDAMEVLGIDPIHRLVVPRVVAATIVAALLNGAVITIGLVGGFVFSVFIQHVSAGAYVGTLTLVTGLPEVIISVVKSATFGLIAGLVGCYRGLTTKGGPKGVGTAVNETLVLCVIALFATNVVLTTIGVRFGTGH
>NC_020559.1|WP_003403065.1|685373_686096_+|FadR-family-transcriptional-regulator-Mce2R
MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEALPSERRLAELLGVSRPAVREALKRLSAAGLVEVRQGDVTTVRDFRRHAGLDLLPRLLFRNGELDISVVRSILEARLRNFPKVAELAAERNEPELAELLQDSLRALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTLAALTTTMTAAAKRPSDYRKLADAICSGDPTGAKKAAQDLLELANTSLMAVLVSQASRQ
>NC_020559.1|WP_003900178.1|682849_685237_-|flippase-like-domain-containing-protein
MRVDGRDIGVSGNLLQPLTRRTNDIIRAVLAAIYLVAVITSSLITRPQWVALEKSISEIVGVLSPSQSDLVYLGYGLAILALPFVILIGLIVSRQWKLLGAYAAAGLMAVLPLSISSSRIAAPRWHFDLSDRLATLLAQFLDDPRWIAMLAAVLTVSGPWLPARWRHWWWALLLAFVPIHLVVSAIVPARSLLGLAVGWLVGALVVLVVGTPALEVPLDGAIRALAKRGFAVSGLAVVRPAGPGPLVLSAACEQPNAGACSEALIELYGPHQSGGGALRQLWLKLTLRGTETAPLQASMRRAVEHRALMAIAFGDLGMANTTVIAVSPLDRGWTLYAHRPARGIGISECTKTTPTAHVWEALRTLHDQQISHGDLCSAEITVDNGAVLFGGFGEAEYGATDAQLQSDLAQLLVTTSALYDAEAAVTAAIDTFGKQAILAASRRLTKSAVPKRIRESITDPNAVIASTRAEVMRQTGADQIKAETITRFSRGQLIQLVLIGALVYVAYPFISTVPTFFSQLRTANWWWALLGLAVSALTYVGAAAALWACADGLVGFWKLSIMQVANTFAATTTPAGVGGLALSTRFLQKGGLTAVRATAAVALQQSVQVIVHLVLLILFSALAGTSTDLSHFVPNATVLYLIAGVALGIVGTFLFVPKLRRWLATAVRPKLREVTNDLIALAREPKRLALIVLGCAGTTLGAALALWASIEAFGGGTTFVTVTVVTMVGGTLASAAPTPGGVGAVEAALIGGLAAFGVPAALGVPSVLLYRLLTCWLPVFAGWQVMHWLTRHEMI
>NC_020559.1|WP_003403055.1|680193_682827_+|glycoside-hydrolase-family-92-protein
MRARRLRRALAALLAVAGLFVPFIVGVPTAYDGEPVFVAIPVEHVNTLIGTGTGAAIVGEINNFPGASVPFGMVQYSPDTVDNYAGYDYDNPHSTGFSMTHASVGCPAFGDISMLPTTTPLGSQPWSAWEEIAHDDTEVGVPGYYTVRFPGTGVIAELTATTRTGVGRFRYPRNGWPALFHVRSGASLAGNYAATLQIEDNTTITGSATSGGFCGKKNLYTVYFAMKFSQPFSSYGTWDGYAVYPGSHSMNSSYSGGYVGFPAGSVLEVRTALSYVSVDGARANLDAEGGASFDDIRAATSSEWNAALSRIAVAGRGPGDVDTFYTCLYRSLLHPNTFNDVDGRYIGFDGVIHSVASGHTHYANFSDWDTYRSLAPLQGLLFPQRASDMIQSLVTDAEQSGAYPRWALANSATGMMSGDSVVPLIVNLYAFGARDFDLKSALHYMVNAATQGGVGLDGFLERPGIAAYLRLGYGPQTAEFRANGRIAGASVTLEWSVDDFAISRFADSLGDTATAAVFQNRSQYWQNLFNPTTGYISPRSAAGFFPDGPGFVAYPSGFGQDGYDEGNAEQYLWWVPHNVAGLVTALGGRTAVVKRLDRFTKKLNVGPNEPYLWAGNEPGFGVPWLYNYIGQPWKTQRTVDRVRGLFGPTPGGAPGNDDLGALSSWYVWAALGLYPSTPGTTILTVNTPLFDRAVIALPTGKSIQITAPGASGRNRLKYIDGLTIDRQPSNQTFLPESIVRTGGDLTFSLAGTPNKVWGTAASAAPPSFGAGSSAVTVNIARPIIGIVPGATGTVTVDAQRMIDGVDDYTVTPTSYVVGIAAEPLSGQFDDDGAVSASVAITVARSVPSGYYPIYVTTSAGDSARTLIVLVVVAEAVE
>NC_020559.1|WP_003403052.1|679353_680040_-|LpqN/LpqT-family-lipoprotein
MKHFTAAVATVALSLALAGCSFNIKTDSAPTTSPTTTSPTTSTTTTSATTSAQAAGPNYTIADYIRDNHIQETPVHHGDPGSPTIDLPVPDDWRLLPESSRAPYGGIVYTQPADPNDPPTIVAILSKLTGDIDPAKVLQFAPGELKNLPGFQGSGDGSAATLGGFSAWQLGGSYSKNGKLRTVAQKTVVIPSQGAVFVLQLNADALDDETMTLMDAANVIDEQTTITP
>NC_020559.1|WP_003403047.1|678886_679294_+|type-II-toxin-antitoxin-system-toxin-ribonuclease-C26
MIIDTSALLAYFDAAEPDHAAVSECIDSSADALVVSPYVVAELDYLVATRVGVDAELAVLRELAGGAWELANCGAAEIEQAARIVTKYQDQRIGIADAANVVLADRYRTRTILTLDRRHFSALRPIGGGRFTVIP
>NC_020559.1|WP_003403119.1|694201_695752_+|MCE-family-protein
MLTRAIKTQLVLLTVLAVIAVVVLGWYFLRIPSLVGIGRYTLYAELPRSGGLYRTANVTYRGITIGKVTGVEPTERGARATMSIDNGYQIPTDASANVHSVSAVGEQFVDLVSTRTSGPYLRHGQTITTTTVPSQIGPALDAANRGLAVLPKDRVASVLHEASEAVGGLGSSLNRLIEATQAIAHDVRGSLEDIDDIIERSAPIIDSQVNSGNEIARWAANLNTLAAQTAQTDPAVRSILANAAPTADQVNATFSDVRESLPQTLANLEVVIDMLKRYHNGVEQALVFLPQSGAIAQSVTTEFPGQAGLGVGGLALNQPPPCLTGFLPASEWRSPADTSTAPLPKGTYCRIPMDASNVVRGARNNPCVDVPGKRAATPRECRSNEAYVPGGTNPWYGDPNQMLSCPAPAARCDQPVKPGQVIPAPSVNNGINPLPADQLPGTPPPVNDPLQRPGSGTVQCNGQQPNPCVYTPSTFPTTIYDVQSGKVVAPDGVVYSVEASTHAGADGWKVMLAPTG
>NC_020559.1|WP_003403122.1|695803_696196_-|type-II-toxin-antitoxin-system-toxin-ribonuclease-C4
MNVRRALADTSVFIGIEATRFDPDRFAGYEWGVSVVTLGELRLGVLQASGPEAAARRLSTYQLAQRFEPLGIDEAVSEAWALLVSKLRAAKLRVPINDSWIAATAVAHGIAILTQDNDYAAMPDVEVITI
>NC_020559.1|WP_003403125.1|696192_696450_-|type-II-toxin-antitoxin-system-antitoxin-VapB4
MSATIPARDLRNHTAEVLRRVAAGEEIEVLKDNRPVARIVPLKRRRQWLPAAEVIGELVRLGPDTTNLGEELRETLTQTTDDVRW
>NC_020559.1|WP_003403128.1|696632_697868_-|ATP-binding-protein
MGVVERAIAPSVLAALADTPVVVVNGARQVGKTTLVARLDYPGSSEVVSLDDVANRDAARDDPRAFVSRPVDTLVIDEAQLEPGLFRAIKAEVDRDRRPGRFLLTGSARLLSAPDMADALVGRVEIIELWPFSQGERAGIADGFVDALFTAPRELIHGSDMRRADLVDRIATGGFPDIVARSPSRRRAWFDNYLTTATQSVIREISPIERLAEMPRVLRLCAARTGAELNVSALANDLSIPARTTAGYLALLEAAFLIHRVPAWSTNLSRKVIRRPKLVVSDSGLACHLLGVTGATLDRPGRPLGPLLETFVANEIRKQLTWSTERPSLWHFRDRGGAEVDLVLEHPDGRVCGIEVKATSTPRAEDLRGLRYLAERLDDRFQFGVLLTAAPEATPFGPTLAALPVSTLWAG
>NC_020559.1|WP_003403137.1|698118_698532_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MKPPLAVDTSVAIPLLVRTHTAHAAVVAWWAHREAALCGHALAETYSVLTRLPRDLRLAPMDAARLLTERFAAPLLLSSRTTEHLPRVLAQFEITGGAVYDALVALAAAEHRAELATRDARAKDTYEKIGVHVVVAA
>NC_020559.1|WP_003403139.1|698528_698765_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MKAVVDAAGRIVVPKPLREALGLQPGSTVEISRYGAGLHLIPTGRTARLEEENGVLVATGETTIDDEVVFGLIDSGRK
>NC_020559.1|WP_003900973.1|698868_699375_-|two-component-system-sensor-kinase-HK1
MPITPLLHESVARFAATGADITTRAEPDLFVSIDPDHLRRILTAVLDNAITHGDGEIAVTAHARDGAVDIGVRDHGPGFADHFLPVAFDRFTRADTARGGRGSGLGLAIVAALTTTHGGHANATNHPDGGAELRITLPTPRPPFHEELPRITSSDTKDPNREHDTSDQ
>NC_020559.1|WP_003403144.1|699488_699959_-|two-component-system-sensor-kinase-HK2
MALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPDPPTS
>NC_020559.1|WP_003403148.1|700002_700764_-|two-component-system-response-regulator-TcrA
MADETTMRAGRGPGRACGRVSGVRILVVEDEPKMTALLARALTEEGHTVDTVADGRHAVAAVDGGDYDAVVLDVMLPGIDGFEVCARLRRQRVWTPVLMLTARGAVTDRIAGLDGGADDYLTKPFNLDELFARLRALSRRGPIPRPPTLEAGDLRLDPSEHRVWRADTEIRLSHKEFTLLEALIRRPGIVHTRAQLLERCWDAAYEARSNIVDVYIRYLRDKIDRPFGVTSLETIRGAGYRLRKDGGRHALPR
>NC_020559.1|WP_003403164.1|700820_701132_+|hypothetical-protein
MNRIVQFGVSAVAAAAIGIGAGSGIAAAFDGEDEVTGPDADRARAAAVQAVPGGTAGEVETETGEGAAAYGVLVTRPDGTRVEVHLDRDFRVLDTEPADGDGG

Crispr_ID: NC_020559_4

• CRISPR_ID: NC_020559_4
• CRISPR_location: 962068-962319
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_020559_4

Consensus_repeat	Method
ACCTGGCGCCACCCGCGCCCGCCGAACTGGCGCCACCCGCGCCCGCCGACCTGGCACCACCCG	PILER-CR

spacers of NC_020559_4

>4.1|962131|47|NC_020559|PILER-CR
CGGCGGGCGCGGGTGGCGCCAGGTCGGCGGACGCGGGTGCCAGATCG
>4.2|962241|56|NC_020559|PILER-CR
AGCTGCCGGGAGGGGTTCACCCAGCGGCGCGGGCAGGTCGTTTACGGCAAGTTCCA

CRISPR arrays and Neighbor proteins around NC_020559_4

CRISPR arrays

The CRISPR arrays of NC_020559_4

>merge|NC_020559|4|962068-962319|PILER-CR
CGGGTGGTGCCAGGTCGGCGGGCGCGGGTGGCGCCAGTTCGGCGGGCGCGGGTGGCGCCAGGTCGGCGGGCGCGGGTGGCGCCAGGTCGGCGGACGCGGGTGCCAGATCGGCGGGTGGCGCCAGTTCGGCGGGAGCTGCCGGGAGGGGTTCACCCAGCGGCGCGGGCAGGTCGTTTACGGCAAGTTCCACGGGTGGTGCCAGGTCGGCGGGCGCGGGTGGCGCCAGGTCGGCGGGCGCGGGTGGCGCCAGGT

>NC_020559|4|2|962068-962319|PILER-CR
CGGGTGGTGCCAGGTCGGCGGGCGCGGGTGGCGCCAGTTCGGCGGGCGCGGGTGGCGCCAGGT	CGGCGGGCGCGGGTGGCGCCAGGTCGGCGGACGCGGGTGCCAGATCG
GCGGGTGGCGCCAGTTCGGCGGGAGCTGCCGGGAGGGGTTCACCCAGCGGCGCGGGCAGGTCG	TTTACGGCAAGTTCCACGGGTGGTGCCAGGTCGGCGGGCGCGGGTGGCGCCAGGTC
GGCGGGCGCGGGTGGCGCCAGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_003404591.1|971301_971790_-|DUF2771-domain-containing-protein	unknown	unknown	gnl|CDD|378520
NC_020559.1|WP_003404564.1|963751_964834_-|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl|CDD|234672
NC_020559.1|WP_003911329.1|960166_960367_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003404549.1|960876_961359_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein	unknown	unknown	gnl|CDD|238451
NC_020559.1|WP_003404552.1|961355_961781_+|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl|CDD|223391
NC_020559.1|WP_003404596.1|973570_974359_+|DUF3027-domain-containing-protein	unknown	unknown	gnl|CDD|378605
NC_020559.1|WP_003898626.1|968000_969953_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173850
NC_020559.1|WP_003404420.1|951160_952354_-|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl|CDD|236095
NC_020559.1|WP_003898622.1|957828_960099_-|helicase-associated-domain-containing-protein	unknown	unknown	gnl|CDD|379300
NC_020559.1|WP_003404418.1|950690_951164_+|SRPBCC-family-protein	unknown	unknown	gnl|CDD|176861
NC_020559.1|WP_003404423.1|952510_953722_+|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl|CDD|236197
NC_020559.1|WP_009938284.1|965910_967740_-|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_020559.1|WP_003404559.1|963469_963748_-|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340452
NC_020559.1|WP_003404586.1|970041_971202_-|FIST-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|226833
NC_020559.1|WP_003404426.1|953726_955889_+|fatty-oxidation-protein-FadB	unknown	unknown	gnl|CDD|183293
NC_020559.1|WP_003404544.1|960376_960880_+|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl|CDD|236483
NC_020559.1|WP_003404570.1|965384_965792_+|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NC_020559.1|WP_003900225.1|971786_973433_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
NC_020559.1|WP_003404566.1|964830_965220_-|YccF-domain-containing-protein	unknown	unknown	gnl|CDD|236975
NC_020559.1|WP_003404428.1|955956_957585_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223989

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_003404591.1|971301_971790_-|DUF2771-domain-containing-protein	gnl|CDD|378520	pfam10969, DUF2771, Protein of unknown function (DUF2771). This bacterial family of proteins has no known function.	1.92145e-65
NC_020559.1|WP_003404564.1|963751_964834_-|GTP-3',8-cyclase-MoaA	gnl|CDD|234672	PRK00164, moaA, GTP 3',8-cyclase MoaA.	5.8311e-172
NC_020559.1|WP_003404426.1|953726_955889_+|fatty-oxidation-protein-FadB	gnl|CDD|183293	PRK11730, fadB, fatty acid oxidation complex subunit alpha FadB.	2.78764e-147
NC_020559.1|WP_003404549.1|960876_961359_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein	gnl|CDD|238451	cd00886, MogA_MoaB, MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea, and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MogA, together with MoeA, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes. In contrast, MoaB shows high similarity to MogA, but little is known about its physiological role. All well studied members of this family form highly stable trimers.	3.3688e-59
NC_020559.1|WP_003404552.1|961355_961781_+|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl|CDD|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	1.91562e-41
NC_020559.1|WP_003404596.1|973570_974359_+|DUF3027-domain-containing-protein	gnl|CDD|378605	pfam11228, DUF3027, Protein of unknown function (DUF3027). This family of proteins with unknown function appears to be restricted to Actinobacteria.	7.88339e-111
NC_020559.1|WP_003898626.1|968000_969953_+|acyl-CoA-dehydrogenase	gnl|CDD|173850	cd01161, VLCAD, Very long chain acyl-CoA dehydrogenase. VLCAD is an acyl-CoA dehydrogenase (ACAD), which is found in the mitochondria of eukaryotes and in some bacteria. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. VLCAD acts as a homodimer.	1.68838e-95
NC_020559.1|WP_003404544.1|960376_960880_+|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl|CDD|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	7.97886e-86
NC_020559.1|WP_003898622.1|957828_960099_-|helicase-associated-domain-containing-protein	gnl|CDD|379300	pfam13625, Helicase_C_3, Helicase conserved C-terminal domain. This domain family is found in a wide variety of helicases and helicase-related proteins.	2.14633e-35
NC_020559.1|WP_003404418.1|950690_951164_+|SRPBCC-family-protein	gnl|CDD|176861	cd07819, SRPBCC_2, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	8.79943e-55
NC_020559.1|WP_003404423.1|952510_953722_+|acetyl-CoA-C-acetyltransferase	gnl|CDD|236197	PRK08242, PRK08242, acetyl-CoA C-acetyltransferase.	0
NC_020559.1|WP_009938284.1|965910_967740_-|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	2.60193e-31
NC_020559.1|WP_003404559.1|963469_963748_-|MoaD/ThiS-family-protein	gnl|CDD|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	5.26592e-15
NC_020559.1|WP_003404586.1|970041_971202_-|FIST-C-terminal-domain-containing-protein	gnl|CDD|226833	COG4398, COG4398, Uncharacterized protein conserved in bacteria [Function unknown].	0
NC_020559.1|WP_003404420.1|951160_952354_-|pyridoxal-phosphate-dependent-aminotransferase	gnl|CDD|236095	PRK07777, PRK07777, putative succinyldiaminopimelate transaminase DapC.	0
NC_020559.1|WP_003900225.1|971786_973433_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.82133e-28
NC_020559.1|WP_003404570.1|965384_965792_+|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.76884e-25
NC_020559.1|WP_003404566.1|964830_965220_-|YccF-domain-containing-protein	gnl|CDD|236975	PRK11770, PRK11770, YccF domain-containing protein.	1.22814e-51
NC_020559.1|WP_003404428.1|955956_957585_-|DEAD/DEAH-box-helicase	gnl|CDD|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	1.05705e-117

Protein sequences

>NC_020559.1|WP_003404552.1|961355_961781_+|molybdenum-cofactor-biosynthesis-protein-MoaE
MTQVLRAALTDQPIFLAEHEELVSHRSAGAIVGFVGMIRDRDGGRGVLRLEYSAHPSAAQVLADLVAEVAEESSGVRAVAASHRIGVLQVGEAALVAAVAADHRRAAFGTCAHLVETIKARLPVWKHQFFEDGTDEWVGSV
>NC_020559.1|WP_003404549.1|960876_961359_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein
MSTRSARIVVVSSRAAAGVYTDDCGPIIAGWLEQHGFSSVQPQVVADGNPVGEALHDAVNAGVDVIITSGGTGISPTDTTPEHTVAVLDYVIPGLADAIRRSGLPKVPTSVLSRGVCGVAGRTLIINLPGSPGGVRDGLGVLADVLDHALEQIAGGDHPR
>NC_020559.1|WP_003404544.1|960376_960880_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MARASGASDYRSGELSHQDERGAAHMVDITEKATTKRTAVAAGILRTSAQVVALISTGGLPKGDALATARVAGIMAAKRTSDLIPLCHQLALTGVDVDFTVGQLDIEITATVRSTDRTGVEMEALTAVSVAALTLYDMIKAVDPGALIDDIRVLHKEGGRRGTWTRR
>NC_020559.1|WP_003911329.1|960166_960367_+|hypothetical-protein
MADIAEGKARKTRYVDHGWPTTDPDDHAVSELVTDRTGALSPFGELTFPVPSDDLPYIHPVTVINR
>NC_020559.1|WP_003898622.1|957828_960099_-|helicase-associated-domain-containing-protein
MTEHTPDIPLGSWLAALPDERLTQLLELRPDLAQPPPGSIAALAARAQARQSVKAATDELDFLRLAVFDALLVLQADTAPVPIVRLLAVIGDRAAQADVLGALADLKQRALAWGETAVRVATDAGTALPWHPGQVTLEGSSRSGDQLADLIAGLDPAQRDVLDKLLQGSPVGRTRDAAPGAPSDRPVPRLLAMGLLRRIDAETVILPRHVGQVLRGEQPGPMELTAPDPVVSTTTPDDADAAAAGAVIDLLREVDVLLENLGATPVAELRSGGLGVREFKRLAKATGIDEPRLGLILEIAAAAGLIASGMPDPEPPHSDGPFWAPTVAADRFATMSPAERWHLLASAWLDLPGRPALIGTRGPDAKPYGALSDSLFSTAAPLDRRLLLGMLAELPAGAGVDASRASATLIWRRPRWARRLQPAPIADLLTEGHALGLVGRGAISTPARALLDEALEPATAPAAAVGVMARALPKPIDHFLVQADLTVVVPGPLQRELADDLTTVATVESAGTAMVYRVSEQSIRHALDVGKSRDWLQEFFANRSKTPVPQGLTYLIDDVARRHGQLRIGMAASFVRCEDPTLLAQVVAAPEADGLALRALAPTVAVSPAPISEVLVTLRGAGFAPAAEDSTGAVVDVRTRGARVPTPQRRRPYRPPPRPNSEALKAVVAVLREVTAAPFANVRVDPAVTMSLLQRAAKDQATLVISYLDAAGVATQRVVAPITLRGGQLVAFDSSSGRLRDFAIHRITLVVSAHDR
>NC_020559.1|WP_003404428.1|955956_957585_-|DEAD/DEAH-box-helicase
MQSDKTVLLEVDHELAGAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAEQVVDALVSYSRYAVPQPLLVDIVDTMARYGRLQLVKNPAHGLTLVSLDRAVLEEVLRNKKIAPMLGARIDDDTVVVHPSERGRVKQLLLKIGWPAEDLAGYVDGEAHPISLHQEGWQLRDYQRLAADSFWAGGSGVVVLPCGAGKTLVGAAAMAKAGATTLILVTNIVAARQWKRELVARTSLTENEIGEFSGERKEIRPVTISTYQMITRRTKGEYRHLELFDSRDWGLIIYDEVHLLPAPVFRMTADLQSKRRLGLTATLIREDGREGDVFSLIGPKRYDAPWKDIEAQGWIAPAECVEVRVTMTDSERMMYATAEPEERYRICSTVHTKIAVVKSILAKHPDEQTLVIGAYLDQLDELGAELGAPVIQGSTRTSEREALFDAFRRGEVATLVVSKVANFSIDLPEAAVAVQVSGTFGSRQEEAQRLGRILRPKADGGGAIFYSVVARDSLDAEYAAHRQRFLAEQGYGYIIRDADDLLGPAI
>NC_020559.1|WP_003404426.1|953726_955889_+|fatty-oxidation-protein-FadB
MPDNTIQWDKDADGIVTLTMDDPSGSTNVMNEAYIESMGKAVDRLVAEKDSITGVVVASAKKTFFAGGDVKTMIQARPEDAGDVFNTVETIKRQLRTLETLGKPVVAAINGAALGGGLEIALACHHRIAADVKGSQLGLPEVTLGLLPGGGGVTRTVRMFGIQNAFVSVLAQGTRFKPAKAKEIGLVDELVATVEELVPAAKAWIKEELKANPDGAGVQPWDKKGYKMPGGTPSSPGLAAILPSFPSNLRKQLKGAPMPAPRAILAAAVEGAQVDFDTASRIESRYFASLVTGQVAKNMMQAFFFDLQAINAGGSRPEGIGKTPIKRIGVLGAGMMGAGIAYVSAKAGYEVVLKDVSLEAAAKGKGYSEKLEAKALERGRTTQERSDALLARITPTADAADFKGVDFVIEAVFENQELKHKVFGEIEDIVEPNAILGSNTSTLPITGLATGVKRQEDFIGIHFFSPVDKMPLVEIIKGEKTSDEALARVFDYTLAIGKTPIVVNDSRGFFTSRVIGTFVNEALAMLGEGVEPASIEQAGSQAGYPAPPLQLSDELNLELMHKIAVATRKGVEDAGGTYQPHPAEAVVEKMIELGRSGRLKGAGFYEYADGKRSGLWPGLRETFKSGSSQPPLQDMIDRMLFAEALETQKCLDEGVLTSTADANIGSIMGIGFPPWTGGSAQFIVGYSGPAGTGKAAFVARARELAAAYGDRFLPPESLLS
>NC_020559.1|WP_003404423.1|952510_953722_+|acetyl-CoA-C-acetyltransferase
MSEEAFIYEAIRTPRGKQKNGSLHEVKPLSLVVGLIDELRKRHPDLDENLISDVILGCVSPVGDQGGDIARAAVLASGMPVTSGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSDGGAMGLDPATNYDVMFVPQGIGADLIATIEGFSREDVDAYALRSQQKAAEAWSGGYFAKSVVPVRDQNGLLILDHDEHMRPDTTKEGLAKLKPAFEGLAALGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAAGKLQGLTPRARIVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASVVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELERRNARRALITLCIGGGMGVATIIERV
>NC_020559.1|WP_003404420.1|951160_952354_-|pyridoxal-phosphate-dependent-aminotransferase
MTVSRLRPYATTVFAEMSALATRIGAVNLGQGFPDEDGPPKMLQAAQDAIAGGVNQYPPGPGSAPLRRAIAAQRRRHFGVDYDPETEVLVTVGATEAIAAAVLGLVEPGSEVLLIEPFYDSYSPVVAMAGAHRVTVPLVPDGRGFALDADALRRAVTPRTRALIINSPHNPTGAVLSATELAAIAEIAVAANLVVITDEVYEHLVFDHARHLPLAGFDGMAERTITISSAAKMFNCTGWKIGWACGPAELIAGVRAAKQYLSYVGGAPFQPAVALALDTEDAWVAALRNSLRARRDRLAAGLTEIGFAVHDSYGTYFLCADPRPLGYDDSTEFCAALPEKVGVAAIPMSAFCDPAAGQASQQADVWNHLVRFTFCKRDDTLDEAIRRLSVLAERPAT
>NC_020559.1|WP_003404418.1|950690_951164_+|SRPBCC-family-protein
MIANLVAVAIRASREVVIEAPPEVIVEALADMDAVPSWSSVHKRVEVVDTYSDGRPHHVKVTIKVAGIVDTELLEYHWGPDWVVWDAAKTAQQHGQHGEYNLRREDNDKTRVRFTLTVEPSAPLPAFWVNIARKKILHAATEGLRKQVVGRRRFTSG
>NC_020559.1|WP_003404559.1|963469_963748_-|MoaD/ThiS-family-protein
MTQVSDESAGIQVTVRYFAAARAAAGAGSEKVTLRSGATVAELIDGLSVRDVRLATVLSRCSYLRDGIVVRDDAVALSAGDTIDVLPPFAGG
>NC_020559.1|WP_003404564.1|963751_964834_-|GTP-3',8-cyclase-MoaA
MTLTALGMPALRSRTNGIADPRVVPTTGPLVDTFGRVANDLRVSLTDRCNLRCSYCMPERGLRWLPGEQLLRPDELARLIHIAVTRLGVTSVRFTGGEPLLAHHLDEVVAATARLRPRPEISLTTNGVGLARRAGALAEAGLDRVNVSLDSIDRAHFAAITRRDRLAHVLAGLAAAKAAGLTPVKVNAVLDPTTGREDVVDLLRFCLERGYQLRVIEQMPLDAGHSWRRNIALSADDVLAALRPHFRLRPDPAPRGSAPAELWLVDAGPNTPRGRFGVIASVSHAFCSTCDRTRLTADGQIRSCLFSTEETDLRRLLRGGADDDAIEAAWRAAMWSKPAGHGINAPDFIQPDRPMSAIGG
>NC_020559.1|WP_003404566.1|964830_965220_-|YccF-domain-containing-protein
MRLILNVIWLVFGGLWLALGYLLASLVCFLLIITIPFGFAALRIASYALWPFGRTIVEKPTAGTGALIGNVIWVLLFGIWLALGHLVSAAAMAVTIIGIPLALANLKLIPVSLVPLGKDIVGVNSQVPT
>NC_020559.1|WP_003404570.1|965384_965792_+|cold-shock-protein
MPTGKVKWYDPDKGFGFLSQEGGEDVYVRSSALPTGVEALKAGQRVEFGIASGRRGPQALSLRLIEPPPSLSRPRREPAAEHKHSPDELHGMVEDMITLLESTVQPELRKGRYPDRKTARRVAEVVRAVAREFES
>NC_020559.1|WP_009938284.1|965910_967740_-|PE-family-protein
MSYVLATPEMVAAAANNLAQIGSTLSAANAAALAPTTGVLAAGADEVSAAVASLFSGHAQAYQTLGTQAAAFHERFIQALSTAAGAYGSAEAANASPLQQALNVINAPTQTLLGRPLIGNGTNGAPGTGQAGGPGGLLYGNGGNGGSGGVGQAGGAGGSAGLIGIGGTGGAGGAGAVGGVGGNGGWLYGNGGAGGLGGTGVAGVNGGMGAAGGAGGNAYLFGSGGAGGQGGMGAAGADGVNPTPTGTADAGSTGTDQTLGGNAIGGNGGPGDAGDAMTSGGAGGSGGNAVSTVNGDAVGGEGGKGGEGAYGGAGGAGGSAASIGNAAIGGNGGAGGNAQAPGGVGGAGGEGGDAQVGTNSPSNAEAGNGGSGGNGFDSFASGGTGGAGGTGGAGGRGGLLIGDGGAGGAGGVGGTGGSGAPGGGGGAGGDGGAANTDSAGSSRKAFGGDGGVGGDGASALGTGGEGGIGGQGGNGGAGGLLIGNGGAGGVGGTAGAGGTGGSGGAGGAGGAGGGGTNSGPGAAFGGNGNTGGNGGNGGAPGALGGKGGSGGLIGRAGSDGGVGAGGAGGAGGAGGTGGEGGTGGDGKTTDGNPGMGGSPGSAGQPGQPG
>NC_020559.1|WP_003898626.1|968000_969953_+|acyl-CoA-dehydrogenase
MAQQTQVTEEQARALAEESRESGWDKPSFAKELFLGRFPLGLIHPFPKPSDAEEARTEAFLVKLREFLDTVDGSVIERAAQIPDEYVKGLAELGCFGLKIPSEYGGLNMSQVAYNRVLMMVTTVHSSLGALLSAHQSIGVPEPLKLAGTAEQKRRFLPRCAAGAISAFLLTEPDVGSDPARMASTATPIDDGQAYELEGVKLWTTNGVVADLLVVMARVPRSEGHRGGISAFVVEADSPGITVERRNKFMGLRGIENGVTRLHRVRVPKDNLIGREGDGLKIALTTLNAGRLSLPAIATGVAKQALKIAREWSVERVQWGKPVGQHEAVASKISFIAATNYALDAVVELSSQMADEGRNDIRIEAALAKLWSSEMACLVGDELLQIRGGRGYETAESLAARGERAVPVEQMVRDLRINRIFEGSSEIMRLLIAREAVDAHLTAAGDLANPKADLRQKAAAAAGASGFYAKWLPKLVFGEGQLPTTYREFGALATHLRFVERSSRKLARNTFYGMARWQASLEKKQGFLGRIVDIGAELFAISAACVRAEAQRTADPVEGEQAYELAEAFCQQATLRVEALFDALWSNTDSIDVRLANDVLEGRYTWLEQGILDQSEGTGPWIASWEPGPSTEANLARRFLTVSPSSEAKL
>NC_020559.1|WP_003404586.1|970041_971202_-|FIST-C-terminal-domain-containing-protein
MRIGVGVCTTPDARQAAVEAAGQARDELAGEAPSLAVLLGSRAHTDRAADVLSAVLQMIDPPALVGCIAQAIVAGRHEIEDEPAVVVWLASGLAAETFQLDFVRTGSGALITGYRFDRTARDLHLLLPDPYTFPSNLLIEHPNTDLPGTAVVGGVVSGGRRRGDTRLFRDHDVLTSGVVGVRLPGMRGVPVVSQGCRPIGYPYIVTGADGILITELGGRPPLQRLREIVEGLSPDERALVSHGLQIGIVVDEHLAAPGQGDFVIRGLLGADPSTGSIEIDEVVQVGATMQFQVRDAAGADKDLRLTVERAAARLPGRAAGALLFTCNGRGRRMFGVADHDASTIEELLGGIPLAGFFAAGEIGPIAGRNALHGFTASMALFVDDME
>NC_020559.1|WP_003404591.1|971301_971790_-|DUF2771-domain-containing-protein
MKRGVATLPVILVILLSVAAGAGAWLLVRGHGPQQPEISAYSHGHLTRVGPYLYCNVVDLDDCQTPQAQGELPVSERYPVQLSVPEVISRAPWRLLQVYQDPANTTSTLFRPDTRLAVTIPTVDPQRGRLTGIVVQLLTLVVDHSGELRDVPHAEWSVRLIF
>NC_020559.1|WP_003900225.1|971786_973433_-|MFS-transporter
MAPTPGRRTRNGSVNGHPGMANYPPDDANYRRSRRPPPMPSANRYLPPLGEQPEPERSRVPPRTTRAGERITVTRAAAMRSREMGSRMYLLVHRAATADGADKSGLTALTWPVMANFAVDSAMAVALANTLFFAAASGESKSRVALYLLITIAPFAVIAPLIGPALDRLQHGRRVALALSFGLRTALAVVLIMNYDGATGSFPSWVLYPCALAMMVFSKSFSVLRSAVTPRVMPPTIDLVRVNSRLTVFGLLGGTIAGGAIAAGVEFVCTHLFQLPGALFVVVAITIAGASLSMRIPRWVEVTSGEVPATLSYHRDRGRLRRRWPEEVKNLGGTLRQPLGRNIITSLWGNCTIKVMVGFLFLYPAFVAKAHEANGWVQLGMLGLIGAAAAVGNFAGNFTSARLQLGRPAVLVVRCTVLVTVLAIAAAVAGSLAATAIATLITAGSSAIAKASLDASLQHDLPEESRASGFGRSESTLQLAWVLGGAVGVLVYTELWVGFTAVSALLILGLAQTIVSFRGDSLIPGLGGNRPVMAEQETTRRGAAVAPQ
>NC_020559.1|WP_003404596.1|973570_974359_+|DUF3027-domain-containing-protein
MTGPTEESAVATVADWPEGLAAVLRGAADQARAAVVEFSGPEAVGDYLGVSYEDGNAATHRFIAHLPGYQGWQWAVVVASYSGADHATISEVVLVPGPTALLAPDWVPWEQRVRPGDLSPGDLLAPAKDDPRLVPGYTASGDAQVDETAAEIGLGRRWVMSAWGRAQSAQRWHDGDYGPGSAMARSTKRVCRDCGFFLPLAGSLGAMFGVCGNELSADGHVVDRQYGCGAHSDTTAPAGGSTPIYEPYDDGVLDIIEKPAES

Crispr_ID: NC_020559_5

• CRISPR_ID: NC_020559_5
• CRISPR_location: 1090695-1090856
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_020559_5

Consensus_repeat	Method
CGGTGCCGGCGGCACCGGCGG	PILER-CR

spacers of NC_020559_5

>5.1|1090716|66|NC_020559|PILER-CR
TGACGGCAGCGGCACCTTCAATGCCCAAGCCAACAACGGCGGCGACGGTGGTGCCGGCGGTGTTGG
>5.2|1090803|33|NC_020559|PILER-CR
CTTCGGCGGAATTAACGGCACGTTCGGCACCAA

CRISPR arrays and Neighbor proteins around NC_020559_5

CRISPR arrays

The CRISPR arrays of NC_020559_5

>merge|NC_020559|5|1090695-1090856|PILER-CR
CGGTGGCGGCGGCGCCGGCGGTGACGGCAGCGGCACCTTCAATGCCCAAGCCAACAACGGCGGCGACGGTGGTGCCGGCGGTGTTGGGGGAGCCGGCGGCACCGGCGGCTTCGGCGGAATTAACGGCACGTTCGGCACCAACGGTGCCGGCGGCACCGGCGG

>NC_020559|5|3|1090695-1090856|PILER-CR
CGGTGGCGGCGGCGCCGGCGG	TGACGGCAGCGGCACCTTCAATGCCCAAGCCAACAACGGCGGCGACGGTGGTGCCGGCGGTGTTGG
GGGAGCCGGCGGCACCGGCGG	CTTCGGCGGAATTAACGGCACGTTCGGCACCAA
CGGTGCCGGCGGCACCGGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_003916757.1|1095874_1096561_+|two-component-system-response-regulator-MrpA	unknown	unknown	gnl|CDD|223816
NC_020559.1|WP_003404949.1|1080627_1081437_-|enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl|CDD|236109
NC_020559.1|WP_003901059.1|1098118_1099513_+|serine-protease-PepD	unknown	unknown	gnl|CDD|273938
NC_020559.1|WP_003900244.1|1082599_1084603_-|acetyl/propionyl-CoA-carboxylase-subunit-alpha	unknown	unknown	gnl|CDD|227111
NC_020559.1|WP_003404939.1|1077243_1077540_+|DUF1490-family-protein	unknown	unknown	gnl|CDD|377826
NC_020559.1|WP_003405053.1|1093499_1093673_+|50S-ribosomal-protein-L32	unknown	unknown	gnl|CDD|234901
NC_020559.1|WP_003898675.1|1104167_1105328_+|hypothetical-protein	unknown	unknown	gnl|CDD|227908
NC_020559.1|WP_148285697.1|1093691_1094249_-|YncE-family-protein	unknown	unknown	gnl|CDD|225926
NC_020559.1|WP_003405128.1|1100077_1100533_-|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl|CDD|234795
NC_020559.1|WP_015345044.1|1077595_1079908_+|copper-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319783
NC_020559.1|WP_003898666.1|1079904_1080537_+|DUF5134-domain-containing-protein	unknown	unknown	gnl|CDD|375044
NC_020559.1|WP_003404935.1|1076827_1077187_+|copper-sensing-transcriptional-repressor-CsoR	unknown	unknown	gnl|CDD|197386
NC_020559.1|WP_003900248.1|1100855_1101602_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NC_020559.1|WP_003900245.1|1084608_1086198_-|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl|CDD|227136
NC_020559.1|WP_003907536.1|1093283_1093478_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003911317.1|1096560_1098075_+|two-component-system-sensor-histidine-kinase-MprB	unknown	unknown	gnl|CDD|223715
NC_020559.1|WP_003898670.1|1086200_1087349_-|acyl-CoA-dehydrogenase-FadE13	unknown	unknown	gnl|CDD|173849
NC_020559.1|WP_003405127.1|1099512_1100058_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein	unknown	unknown	gnl|CDD|238451
NC_020559.1|WP_003898667.1|1081436_1082603_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173838
NC_020559.1|WP_003404960.1|1087345_1089028_-|DUF1446-domain-containing-protein	unknown	unknown	gnl|CDD|377804

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_003916757.1|1095874_1096561_+|two-component-system-response-regulator-MrpA	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.06841e-88
NC_020559.1|WP_003404949.1|1080627_1081437_-|enoyl-CoA-hydratase-family-protein	gnl|CDD|236109	PRK07827, PRK07827, enoyl-CoA hydratase family protein.	1.33711e-148
NC_020559.1|WP_003404960.1|1087345_1089028_-|DUF1446-domain-containing-protein	gnl|CDD|377804	pfam07287, AtuA, Acyclic terpene utilisation family protein AtuA. This family consists of several bacterial and plant proteins of around 400 residues in length. One member of this family has been characterized in Pseudomonas citronellolis as AtuA, a member of a gene cluster that is essential for the acyclic terpene utilisation (Atu) pathway.	0
NC_020559.1|WP_003900244.1|1082599_1084603_-|acetyl/propionyl-CoA-carboxylase-subunit-alpha	gnl|CDD|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
NC_020559.1|WP_003404939.1|1077243_1077540_+|DUF1490-family-protein	gnl|CDD|377826	pfam07371, DUF1490, Protein of unknown function (DUF1490). This family consists of several hypothetical bacterial proteins of around 90 residues in length. Members of the family seem to be found exclusively in Mycobacterium species. The function of this family is unknown.	1.3634e-28
NC_020559.1|WP_003900248.1|1100855_1101602_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.44085e-116
NC_020559.1|WP_003898675.1|1104167_1105328_+|hypothetical-protein	gnl|CDD|227908	COG5621, COG5621, Predicted secreted hydrolase [General function prediction only].	2.05144e-166
NC_020559.1|WP_148285697.1|1093691_1094249_-|YncE-family-protein	gnl|CDD|225926	COG3391, COG3391, Uncharacterized conserved protein [Function unknown].	5.60233e-24
NC_020559.1|WP_015345044.1|1077595_1079908_+|copper-translocating-P-type-ATPase	gnl|CDD|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_020559.1|WP_003898666.1|1079904_1080537_+|DUF5134-domain-containing-protein	gnl|CDD|375044	pfam17197, DUF5134, Domain of unknown function (DUF5134). Proteins in this family are uncharacterized, but have been identified as members of a gene cluster for the synthesis of the tetramic-acid antibiotic streptolydigin, which inhibits bacterial RNA polymerase (RNAP).	4.2756e-25
NC_020559.1|WP_003405128.1|1100077_1100533_-|large-conductance-mechanosensitive-channel-protein-MscL	gnl|CDD|234795	PRK00567, mscL, large-conductance mechanosensitive channel protein MscL.	7.98759e-52
NC_020559.1|WP_003901059.1|1098118_1099513_+|serine-protease-PepD	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	1.33339e-81
NC_020559.1|WP_003900245.1|1084608_1086198_-|acyl-CoA-carboxylase-subunit-beta	gnl|CDD|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NC_020559.1|WP_003404935.1|1076827_1077187_+|copper-sensing-transcriptional-repressor-CsoR	gnl|CDD|197386	cd10151, TthCsoR-like_DUF156, Thermus thermophilus CsoR, a Cu(I)-sensing transcriptional regulator, and related domains; this domain family was previously known as part of DUF156. This domain family contains various Cu(I)-inducible transcriptional regulators including CsoR (copper-sensitive operon repressor) from Mycobacterium tuberculosis (MtCsoR), and Thermus thermophilus (TthCsoR). CsoR regulates the expression of genes involved in copper homeostasis. For example, TthCsoR binds the promoter region of the copZ-csoR-copA operon, and represses expression of these genes, which encode the copper chaperone CopZ, CsoR, and the copper efflux P-type ATPase CopA, respectively. In the presence of excess Cu(I), TthCsoR binds this ion, and is released from the DNA, allowing expression of the downstream genes. TthCsoR also senses other metal ions such as Cu(II), Zn(II), Ag(I), Cd(II) and Ni(II). MtCsoR regulates an operon that includes CsoR and a putative copper transporter gene, ctpV (cation transporter P-type ATPase). CsoRs form a homotetramer (dimer of dimers). In MtCsoR, within each dimer, two Cys residues on opposite subunits, along with a His residue, bind the Cu(I) ion (forming a triagonal S2N coordination complex, C-H-C). These residues are conserved in some but not all members of this family; for example, for TthCsoR, there is a His instead of the second Cys as well as an N-terminal His (not found in those family members having C-H-C) which may also be involved in metal binding (H-C-H-H). A conserved Tyr and a Glu residue facilitate allosteric regulation of DNA binding.	4.77618e-40
NC_020559.1|WP_003911317.1|1096560_1098075_+|two-component-system-sensor-histidine-kinase-MprB	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.43447e-47
NC_020559.1|WP_003898670.1|1086200_1087349_-|acyl-CoA-dehydrogenase-FadE13	gnl|CDD|173849	cd01160, LCAD, Long chain acyl-CoA dehydrogenase. LCAD is an acyl-CoA dehydrogenases (ACAD), which is found in the mitochondria of eukaryotes and in some prokaryotes. It catalyzes the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of LCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. LCAD acts as a homodimer.	6.69283e-128
NC_020559.1|WP_003405127.1|1099512_1100058_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein	gnl|CDD|238451	cd00886, MogA_MoaB, MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea, and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MogA, together with MoeA, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes. In contrast, MoaB shows high similarity to MogA, but little is known about its physiological role. All well studied members of this family form highly stable trimers.	6.45353e-50
NC_020559.1|WP_003898667.1|1081436_1082603_-|acyl-CoA-dehydrogenase	gnl|CDD|173838	cd00567, ACAD, Acyl-CoA dehydrogenase. Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).	5.04144e-95
NC_020559.1|WP_003405053.1|1093499_1093673_+|50S-ribosomal-protein-L32	gnl|CDD|234901	PRK01110, rpmF, 50S ribosomal protein L32; Validated.	1.27689e-09

Protein sequences

>NC_020559.1|WP_003404960.1|1087345_1089028_-|DUF1446-domain-containing-protein
MRIGNCSGFYGDRLSAMREMLTGGELDYLTGDYLAELTMLILGRDRMKNPDRGYAKTFLAQLEDCLGLAHDRGVRIVTNAGGLNPAGLANAVRALAARLGIPAQVAHVEGDDLQPRAAELGLGTPLTANAYLGAWGIVDCFERGADVVVTGRVTDASVVVGAAAAHFGWGRTDYHRLAGAVVAGHVIECGVQATGGNYAFFTEIGDLTHAGFPLAEIAADGSSVITKHHGTGGLVSVDTITAQLLYEITGARYANPDVTARMDSVELSPDGPDRVRISGVIGEPPPPTYKVSLNSIGGFRNAMTFVLTGLDIDAKADLVRRQLEAALTVKPAELQWTLARTDHPDADTEETASALLTCVARDPDPANVGRQFSSAAVELALASYPGFTATAPPGDGQVYGVFTPGYVDAGKVAHIAVHADGTRTEIPCATETLELAPAHPPALPDPLPAGPTRRVPLGLIAGARSGDKGGSANVGVWVRTDEQWRWLAHTLTVELLKELLPETAGLVVTRHVLPNLRALNFVIEAILGQGVAYQARFDPQAKGLGEWLRSRHVEIPETLL
>NC_020559.1|WP_003898670.1|1086200_1087349_-|acyl-CoA-dehydrogenase-FadE13
MNIWTTPERQQLRKTVRAFAEREILPHVDEWERIGELPRGLHRLAGAAGLLGAGFPEAVGGGGGDGADPVIICEEMHQAGAPGGVYASLFTCGIAVPHMVASGDERLIATYVRPTLAGEKIGALAITEPGGGSDVGHLRTSAVRDGDHYVINGAKTYITSGVRADYVVTAVRTGGPGAAGVSLLVVEKDTPGFEVTRKLDKMGWRSSDTAELCYTDVAVPATNLVGAENSGFTQIARAFVSERIGLAAQAYSSAQRCLDLTAQWCRDRETFGRPLISRQSVQNTLAEMARRIDVARVYAHHVVERQLAGETDLIAQVCFAKNTAVQAGEWVANQAVQLFGGMGYMAESEVERQYRDMRILGIGGGTTEILTALAAKTLGYQS
>NC_020559.1|WP_003900245.1|1084608_1086198_-|acyl-CoA-carboxylase-subunit-beta
MLQSTLDPNASAYDEAAATMSGKLDEINAELAKALAGGGPKYVDRHHARGKLTPRERIELLVDPDSPFLELSPLAAYGSNFQIGASLVTGIGAVCGVECMIVANDPTVKGGTSNPWTLRKILRANQIAFENRLPVISLVESGGADLPTQKEIFIPGGQMFRDLTRLSAAGIPTIALVFGNSTAGGAYVPGMSDHVVMIKERSKVFLAGPPLVKMATGEESDDESLGGAEMHARISGLADYFALDELDAIRIGRRIVARLNWIKQGPAPAPVTEPLFDAEELIGIVPPDLRIPFDPREVIARIVDGSEFDEFKPLYGSSLVTGWARLHGYPLGILANARGVLFSEESQKATQFIQLANRADTPLLFLHNTTGYMVGKDYEEGGMIKHGSMMINAVSNSTVPHISLLIGASYGAGHYGMCGRAYDPRFLFAWPSAKSAVMGGAQLSGVLSIVARAAAEARGQQVDEAADAAMRAAVEGQIEAESLPLVLSGMLYDDGVIDPRDTRTVLGMCLSAIANGPIKGTSNFGVFRM
>NC_020559.1|WP_003900244.1|1082599_1084603_-|acetyl/propionyl-CoA-carboxylase-subunit-alpha
MGITRVLVANRGEIARRVFATCRRLGLGTVAVYTDPDAAAPHVAEADARVRLPQTTDYLNAEAIIAAAQAAGADAVHPGYGFLSENAEFAAAVQEAGLTWVGPPVDAVRAMGSKIESKKLMAAAGVPVLEELDPDAVTTAQLPVLVKASAGGGGRGMRVVHELSALPAEVEAARREAQSAFGDPTVFCERYLPTGHHVEVQVMADTHGTVWAVGERECSIQRRHQKIIEEAPSPLVERVPGMRAKLFDAARLAASAIGYTGAGTVEFLADDSPGREGEFYFLEMNTRLQVEHPVTEETTGLDLVELQLMIADCGRLDTEPPPAQGYSIEARLYAEDPAHGWQPQAGVMHTIEVPGVRAQFDSLGQRTGIRLDSGIVDGSTVSIHYDPMLAKVVSYGATRRQAALVLADALVRARLHGLRTNRELLVNVLRHPAFLDGATDTGFFDTHGMAELSTPLADTATLRLSAIAAALADAEHNRASAGVFSSIPSGWRNLASGYQVKTYRDDADTEHRVEYRFTRTGLALPGDPVVQLVSADVDQVVLAQDGVAHGFTVARHGPDVYVDSARGPVHLVALSRFPEPSSAVEQGSLVAPMPGNVIRIGAEVGDTVTAGQPLIWLEAMKMEHTIAAPADGVLTHVSVNTGQQVEVGAILARVEAPQNGPAEGDSP
>NC_020559.1|WP_003898667.1|1081436_1082603_-|acyl-CoA-dehydrogenase
MTDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSELWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAAAGSALLLMVVSPAINGTIIAKFGTDDQKKRWLPGIADGSLTMAFAITEPDAGSNSHKITTTARRDGSDWIIKGQKVFISGIDQAQAVLVVGRSEEAKTGKLRPALFVVPTDAPGFSYTPIEMELVSPERQFQVFLDDVRLPADALVGAEDAAIAQLFAGLNPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGAHQGLAHPLAQCHIEVELAKLMTQKAATLYDHGDDFGAAEAANMAKYAAAEASSRAVDQAVQSMGGNGLTKEYGVAAMMTSARLARIAPISREMVLNFVAQTSLGLPRSY
>NC_020559.1|WP_003404949.1|1080627_1081437_-|enoyl-CoA-hydratase-family-protein
MDSPVDYAGPAACGGPFARLTLNSPHNRNALSSTLVSQLHQGLSAAEADPAVRLVVLGHTGGTFCAGADLSEAGGGGGDPYRMAVARAREMTALLRAIVESPLPVVGAINGHVRAGGFGLVGACDMVVAGPESTFALTEARIGVAPAIISLTLLPKLSPRAAARYYLTGEKFGAREAADIGLITMAADDVDAAVAALVADVGRGSPQGLAASKALTTAAVLEGFDRDAERLTEESARLFVSDEAREGMLAFLQKRPPRWVQPATMRAAD
>NC_020559.1|WP_003898666.1|1079904_1080537_+|DUF5134-domain-containing-protein
MIHDLMLRWVVTGLFVLTAAECGLAIIAKRRPWTLIVNHGLHFAMAVAMAVMAWPWGARVPTTGPAVFFLLAAVWFGATAVVAVRGTATRGLYGYHGLMMLATAWMYAAMNPRLLPVRSCTEYATEPDGSMPAMDMTAMNMPPNSGSPIWFSAVNWIGTVGFAVAAVFWACRFVMERRQEATQSRLPGSIGQAMMAAGMAMLFFAMLFPV
>NC_020559.1|WP_015345044.1|1077595_1079908_+|copper-translocating-P-type-ATPase
MRVCVTGFNVDAVRAVAIEETVSQVTGVHAVHAYPRTASVVIWYSPELGDTAAVLSAITKAQHVPAELVPARAPHSAGVRGVGVVRKITGGIRRMLSRPPGVDKPLKASRCGGRPRGPVRGSASWPGEQNRRERRTWLPRVWLALPLGLLALGSSMFFGAYPWAGWLAFAATLPVQFVAGWPILRGAVQQARALTSNMDTLIALGTLTAFVYSTYQLFAGGPLFFDTSALIIAFVVLGRHLEARATGKASEAISKLLELGAKEATLLVDGQELLVPVDQVQVGDLVRVRPGEKIPVDGEVTDGRAAVDESMLTGESVPVEKTAGDRVAGATVNLDGLLTVRATAVGADTALAQIVRLVEQAQGDKAPVQRLADRVSAVFVPAVIGVAVATFAGWTLIAANPVAGMTAAVAVLIIACPCALGLATPTAIMVGTGRGAELGILVKGGEVLEASKKIDTVVFDKTGTLTRARMRVTDVIAGQRRQPDQVLRLAAAVESGSEHPIGAAIVAAAHERGLAIPAANAFTAVAGHGVRAQVNGGPVVVGRRKLVDEQHLVLPDHLAAAAVEQEERGRTAVFVGQDGQVVGVLAVADTVKDDATDVVGRLHAMGLQVAMITGDNARTAAAIAKQVGIEKVLAEVLPQDKVAEVRRLQDQGRVVAMVGDGVNDAPALVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVRAIELSRQTLRTIYQNLGWAFGYNTAAIPLAALGALNPVVAGAAMGFSSVSVVTNSLRLRRFGRDGRTA
>NC_020559.1|WP_003404939.1|1077243_1077540_+|DUF1490-family-protein
MVWHGFLAKAVPTVVTGAVGVAAYEALRKMVVKAPLRAATVSVAAWGIRLAREAERKAGESAEQARLMFADVLAEASERAGEEVPPLAVAGSDDGHDH
>NC_020559.1|WP_003404935.1|1076827_1077187_+|copper-sensing-transcriptional-repressor-CsoR
MSKELTAKKRAALNRLKTVRGHLDGIVRMLESDAYCVDVMKQISAVQSSLERANRVMLHNHLETCFSTAVLDGHGQAAIEELIDAVKFTPALTGPHARLGGAAVGESATEEPMPDASNM
>NC_020559.1|WP_003907536.1|1093283_1093478_-|hypothetical-protein
MGFRTQVGAATIASTMTWRIPVEDGPAQFRAGVGPGRDRQFTVVAPMVVGLWDRNRRPGWQWPS
>NC_020559.1|WP_003405053.1|1093499_1093673_+|50S-ribosomal-protein-L32
MAVPKRRKSRSNTRSRRSQWKAAKTELVGVTVAGHAHKVPRRLLKAARLGLIDFDKR
>NC_020559.1|WP_148285697.1|1093691_1094249_-|YncE-family-protein
MPVRLDPTGVVTTITHASFNDPHGVAVNPGGNIYVTNQGSNTVSVIDPVTNTVTGSITDGNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPNTNTVTGSIPVGTGAYGVAVNPGGNIYVTNQFSNTVSVIDPATNTVTGSPIPVGLDPTGVAVNPVTGVVYVTNSLDDTVSVITGEPARSVCSAAI
>NC_020559.1|WP_003916757.1|1095874_1096561_+|two-component-system-response-regulator-MrpA
MRILVVDDDRAVRESLRRSLSFNGYSVELAHDGVEALDMIASDRPDALVLDVMMPRLDGLEVCRQLRGTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTKPEDAAESMAMRFSDLTLDPVTREVNRGQRRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVYVGYLRRKTEADGEPRLIHTVRGVGYVLRETPP
>NC_020559.1|WP_003911317.1|1096560_1098075_+|two-component-system-sensor-histidine-kinase-MprB
MWWFRRRDRAPLRATSSLSLRWRVMLLAMSMVAMVVVLMSFAVYAVISAALYSDIDNQLQSRAQLLIASGSLAADPGKAIEGTAYSDVNAMLVNPGQSIYTAQQPGQTLPVGAAEKAVIRGELFMSRRTTADQRVLAIRLTNGSSLLISKSLKPTEAVMNKLRWVLLIVGGIGVAVAAVAGGMVTRAGLRPVGRLTEAAERVARTDDLRPIPVFGSDELARLTEAFNLMLRALAESRERQARLVTDAGHELRTPLTSLRTNVELLMASMAPGAPRLPKQEMVDLRADVLAQIEELSTLVGDLVDLSRGDAGEVVHEPVDMADVVDRSLERVRRRRNDILFDVEVIGWQVYGDTAGLSRMALNLMDNAAKWSPPGGHVGVRLSQLDASHAELVVSDRGPGIPVQERRLVFERFYRSASARALPGSGLGLAIVKQVVLNHGGLLRIEDTDPGGQPPGTSIYVLLPGRRMPIPQLPGATAGARSTDIENSRGSANVISVESQSTRAT
>NC_020559.1|WP_003901059.1|1098118_1099513_+|serine-protease-PepD
MAKLARVVGLVQEEQPSDMTNHPRYSPPPQQPGTPGYAQGQQQTYSQQFDWRYPPSPPPQPTQYRQPYEALGGTRPGLIPGVIPTMTPPPGMVRQRPRAGMLAIGAVTIAVVSAGIGGAAASLVGFNRAPAGPSGGPVAASAAPSIPAANMPPGSVEQVAAKVVPSVVMLETDLGRQSEEGSGIILSAEGLILTNNHVIAAAAKPPLGSPPPKTTVTFSDGRTAPFTVVGADPTSDIAVVRVQGVSGLTPISLGSSSDLRVGQPVLAIGSPLGLEGTVTTGIVSALNRPVSTTGEAGNQNTVLDAIQTDAAINPGNSGGALVNMNAQLVGVNSAIATLGADSADAQSGSIGLGFAIPVDQAKRIADELISTGKASHASLGVQVTNDKDTPGAKIVEVVAGGAAANAGVPKGVVVTKVDDRPINSADALVAAVRSKAPGATVALTFQDPSGGSRTVQVTLGKAEQ
>NC_020559.1|WP_003405127.1|1099512_1100058_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein
MKVAAQCSKLGYTVAPMEQRAELVVGRALVVVVDDRTAHGDEDHSGPLVTELLTEAGFVVDGVVAVSADEVEIRNALNTAVIGGVDLVVSVGGTGVTPRDVTPEATRDILDREILGIAEAIRASGLSAGIVDAGLSRGLAGVSGSTLVVNLAGSRYAVRDGMATLNPLAAQIIGQLSSLEI
>NC_020559.1|WP_003405128.1|1100077_1100533_-|large-conductance-mechanosensitive-channel-protein-MscL
MLKGFKEFLARGNIVDLAVAVVIGTAFTALVTKFTDSIITPLINRIGVNAQSDVGILRIGIGGGQTIDLNVLLSAAINFFLIAFAVYFLVVLPYNTLRKKGEVEQPGDTQVVLLTEIRDLLAQTNGDSPGRHGGRGTPSPTDGPRASTESQ
>NC_020559.1|WP_003900248.1|1100855_1101602_+|ABC-transporter-ATP-binding-protein
MNRQPIVQLSNLSWTFREGETRRQVLDHITFDFEPGEFVALLGQSGSGKSTLLNLISGIEKPTTGDVTINGFAITQKTERDRTLFRRDQIGIVFQFFNLIPTLTVLENITLPQELAGVSQRKAAVVARDLLEKVGMADRERTFPDKLSGGEQQRVAISRALAHNPMLVLADEPTGNLDSDTGDKVLDVLLDLTRQAGKTLIMATHSPSMTQHADRVVNLQGGRLIPAVNRENQTDQPASTILLPTSYE
>NC_020559.1|WP_003898675.1|1104167_1105328_+|hypothetical-protein
MRKAGLTGVVLVLTLTLVAFWWWQRPRTNAVAADSLVGVLVDENNAGYSLATVPGAVRFPRDLGPHYDYQTEWWYYTGNLETADGRLFGYQLTFFRRALAPPGEGVAIADASSWRTTQVYMAHFAISDISNRGFYPAEKFSRQALGLAGASSEPYAVWLDDWYARESNNNSVQLFARTQNTVLDLTLTQTLPPILQGNAGLSVKGAQPGNASNYYSLVRQESRGTVSVNGDTFMVSGLSWKDHEYMTSALAPEDVGWDWFGLQFYNGTALMLFQIRQADGSVTRFSSGTFVAGDGGVIPLESSDFRIKTTDRWTSDQSGATYPIAWEIEIERIGLTLRGAALMANQELRLSRTYWEGAVALEGRYQGMPISGRGYVEMTGYVQRLS

Crispr_ID: NC_020559_6

• CRISPR_ID: NC_020559_6
• CRISPR_location: 1094365-1094525
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_020559_6

Consensus_repeat	Method
CCGTCAGGGATGGAGCCGGTGACGGTGTTGGTG	PILER-CR

spacers of NC_020559_6

>6.1|1094398|54|NC_020559|PILER-CR
TTCGGGTTGATCACCGACACCGATGTTGCTGTTGAAGTTGGTCACGAAGACCAG
>6.2|1094485|25|NC_020559|PILER-CR
ATCCGCCACCCCGCTTGGACCGTTG

CRISPR arrays and Neighbor proteins around NC_020559_6

CRISPR arrays

The CRISPR arrays of NC_020559_6

>merge|NC_020559|6|1094365-1094525|PILER-CR
CCGTCAGGGATGGAGCCGGTGACGGTGTTGGTGTTCGGGTTGATCACCGACACCGATGTTGCTGTTGAAGTTGGTCACGAAGACCAGGCCGGTGACGGTGTTGATCCGCCACCCCGCTTGGACCGTTGCCGTCGGTGATGGAGCCGGTGACGGTGTTGGTG

>NC_020559|6|4|1094365-1094525|PILER-CR
CCGTCAGGGATGGAGCCGGTGACGGTGTTGGTG	TTCGGGTTGATCACCGACACCGATGTTGCTGTTGAAGTTGGTCACGAAGACCAG
GCCGGTGACGGTGTTGATCCGCCACCCCGCTTG	GACCGTTGCCGTCGGTGATGGAGCC
GGTGACGGTGTTGGTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_003916757.1|1095874_1096561_+|two-component-system-response-regulator-MrpA	unknown	unknown	gnl|CDD|223816
NC_020559.1|WP_003404949.1|1080627_1081437_-|enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl|CDD|236109
NC_020559.1|WP_003901059.1|1098118_1099513_+|serine-protease-PepD	unknown	unknown	gnl|CDD|273938
NC_020559.1|WP_003404960.1|1087345_1089028_-|DUF1446-domain-containing-protein	unknown	unknown	gnl|CDD|377804
NC_020559.1|WP_003900248.1|1100855_1101602_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NC_020559.1|WP_003898675.1|1104167_1105328_+|hypothetical-protein	unknown	unknown	gnl|CDD|227908
NC_020559.1|WP_003405136.1|1105456_1106434_-|polyprenyl-diphosphate-synthase-GrcC	unknown	unknown	gnl|CDD|223220
NC_020559.1|WP_148285697.1|1093691_1094249_-|YncE-family-protein	unknown	unknown	gnl|CDD|225926
NC_020559.1|WP_003405128.1|1100077_1100533_-|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl|CDD|234795
NC_020559.1|WP_003405142.1|1107223_1107556_-|FmdB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225210
NC_020559.1|WP_003900244.1|1082599_1084603_-|acetyl/propionyl-CoA-carboxylase-subunit-alpha	unknown	unknown	gnl|CDD|227111
NC_020559.1|WP_015456194.1|1089225_1091202_+|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_020559.1|WP_003900245.1|1084608_1086198_-|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl|CDD|227136
NC_020559.1|WP_003907536.1|1093283_1093478_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003911317.1|1096560_1098075_+|two-component-system-sensor-histidine-kinase-MprB	unknown	unknown	gnl|CDD|223715
NC_020559.1|WP_003898670.1|1086200_1087349_-|acyl-CoA-dehydrogenase-FadE13	unknown	unknown	gnl|CDD|173849
NC_020559.1|WP_003405127.1|1099512_1100058_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein	unknown	unknown	gnl|CDD|238451
NC_020559.1|WP_003898677.1|1106494_1107151_-|flagella-basal-body-P-ring-formation-protein-FlgA	unknown	unknown	gnl|CDD|212159
NC_020559.1|WP_003898667.1|1081436_1082603_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173838
NC_020559.1|WP_003405053.1|1093499_1093673_+|50S-ribosomal-protein-L32	unknown	unknown	gnl|CDD|234901

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_003916757.1|1095874_1096561_+|two-component-system-response-regulator-MrpA	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.06841e-88
NC_020559.1|WP_003404949.1|1080627_1081437_-|enoyl-CoA-hydratase-family-protein	gnl|CDD|236109	PRK07827, PRK07827, enoyl-CoA hydratase family protein.	1.33711e-148
NC_020559.1|WP_003901059.1|1098118_1099513_+|serine-protease-PepD	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	1.33339e-81
NC_020559.1|WP_003404960.1|1087345_1089028_-|DUF1446-domain-containing-protein	gnl|CDD|377804	pfam07287, AtuA, Acyclic terpene utilisation family protein AtuA. This family consists of several bacterial and plant proteins of around 400 residues in length. One member of this family has been characterized in Pseudomonas citronellolis as AtuA, a member of a gene cluster that is essential for the acyclic terpene utilisation (Atu) pathway.	0
NC_020559.1|WP_003900248.1|1100855_1101602_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.44085e-116
NC_020559.1|WP_003898675.1|1104167_1105328_+|hypothetical-protein	gnl|CDD|227908	COG5621, COG5621, Predicted secreted hydrolase [General function prediction only].	2.05144e-166
NC_020559.1|WP_003405136.1|1105456_1106434_-|polyprenyl-diphosphate-synthase-GrcC	gnl|CDD|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	2.83963e-87
NC_020559.1|WP_148285697.1|1093691_1094249_-|YncE-family-protein	gnl|CDD|225926	COG3391, COG3391, Uncharacterized conserved protein [Function unknown].	5.60233e-24
NC_020559.1|WP_003405128.1|1100077_1100533_-|large-conductance-mechanosensitive-channel-protein-MscL	gnl|CDD|234795	PRK00567, mscL, large-conductance mechanosensitive channel protein MscL.	7.98759e-52
NC_020559.1|WP_003405142.1|1107223_1107556_-|FmdB-family-transcriptional-regulator	gnl|CDD|225210	COG2331, COG2331, Uncharacterized protein conserved in bacteria [Function unknown].	3.04455e-36
NC_020559.1|WP_003900244.1|1082599_1084603_-|acetyl/propionyl-CoA-carboxylase-subunit-alpha	gnl|CDD|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
NC_020559.1|WP_015456194.1|1089225_1091202_+|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.06496e-30
NC_020559.1|WP_003900245.1|1084608_1086198_-|acyl-CoA-carboxylase-subunit-beta	gnl|CDD|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NC_020559.1|WP_003911317.1|1096560_1098075_+|two-component-system-sensor-histidine-kinase-MprB	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.43447e-47
NC_020559.1|WP_003898670.1|1086200_1087349_-|acyl-CoA-dehydrogenase-FadE13	gnl|CDD|173849	cd01160, LCAD, Long chain acyl-CoA dehydrogenase. LCAD is an acyl-CoA dehydrogenases (ACAD), which is found in the mitochondria of eukaryotes and in some prokaryotes. It catalyzes the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of LCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. LCAD acts as a homodimer.	6.69283e-128
NC_020559.1|WP_003405127.1|1099512_1100058_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein	gnl|CDD|238451	cd00886, MogA_MoaB, MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea, and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MogA, together with MoeA, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes. In contrast, MoaB shows high similarity to MogA, but little is known about its physiological role. All well studied members of this family form highly stable trimers.	6.45353e-50
NC_020559.1|WP_003898677.1|1106494_1107151_-|flagella-basal-body-P-ring-formation-protein-FlgA	gnl|CDD|212159	cd11614, SAF_CpaB_FlgA_like, SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB. FlgA is a putative periplasmic chaperone that assists in the formation of the flagellar P ring; CpaB is a protein invoved in the assembly of the flp pili, which are bacterial virulence factors mediating non-specific adherence to surfaces; these proteins appear to contain a single SAF domain. This intermediate family also contains the SAF domains of sialic acid synthetases and type III antifreeze proteins, which also share the same extensive core structure.	1.1146e-10
NC_020559.1|WP_003898667.1|1081436_1082603_-|acyl-CoA-dehydrogenase	gnl|CDD|173838	cd00567, ACAD, Acyl-CoA dehydrogenase. Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).	5.04144e-95
NC_020559.1|WP_003405053.1|1093499_1093673_+|50S-ribosomal-protein-L32	gnl|CDD|234901	PRK01110, rpmF, 50S ribosomal protein L32; Validated.	1.27689e-09

Protein sequences

>NC_020559.1|WP_148285697.1|1093691_1094249_-|YncE-family-protein
MPVRLDPTGVVTTITHASFNDPHGVAVNPGGNIYVTNQGSNTVSVIDPVTNTVTGSITDGNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPNTNTVTGSIPVGTGAYGVAVNPGGNIYVTNQFSNTVSVIDPATNTVTGSPIPVGLDPTGVAVNPVTGVVYVTNSLDDTVSVITGEPARSVCSAAI
>NC_020559.1|WP_003405053.1|1093499_1093673_+|50S-ribosomal-protein-L32
MAVPKRRKSRSNTRSRRSQWKAAKTELVGVTVAGHAHKVPRRLLKAARLGLIDFDKR
>NC_020559.1|WP_003907536.1|1093283_1093478_-|hypothetical-protein
MGFRTQVGAATIASTMTWRIPVEDGPAQFRAGVGPGRDRQFTVVAPMVVGLWDRNRRPGWQWPS
>NC_020559.1|WP_015456194.1|1089225_1091202_+|PE-family-protein
MSFVVTAPPVLASAASDLGGIASMISEANAMAAVRTTALAPAAADEVSAAIAALFSSYARDYQTLSVQVTAFHVQFAQTLTNAGQLYAVVDVGNGVLLKTEQQVLGVINAPTQTLVGRPLIGDGTHGAPGTGQNGGAGGILWGNGGNGGSGAPGQPGGRGGDAGLFGHGGHGGVGGPGIAGAAGTAGLPGGNGANGGSGGIGGAGGAGGNGGLLFGNGGAGGQGGSGGLGGSGGTGGAGMAAGPAGGTGGIGGIGGIGGAGGVGGHGSALFGHGGINGDGGTGGMGGQGGAGGSGWAAEGITVGIGEQGGQGGDGGAGGAGGIGGSAGGIGGSQGAGGHGGDGGQGGAGGSGGVGGGGAGAGGDGGAGGIGGTGGNGSIGGAAGNGGNGGRGGAGGMATAGSDGGNGGGGGNGGVGVGSAGGAGGTGGDGGAAGAGGAPGHGYFQQPAPQGLPIGTGGTGGEGGAGGAGGDGGQGDIGFDGGRGGDGGPGGGGGAGGDGSGTFNAQANNGGDGGAGGVGGAGGTGGFGGINGTFGTNGAGGTGGLGTLLGGHNGNIGLNGATGGIGSTTLTNGDRTAAAGEYHRAGGIHLLKRRPNGARAARHRIHRSGHGQPIPDAELRPRHRDGHRRLRRRADLQLQHLLNDGGFRQWPSHPADQR
>NC_020559.1|WP_003404960.1|1087345_1089028_-|DUF1446-domain-containing-protein
MRIGNCSGFYGDRLSAMREMLTGGELDYLTGDYLAELTMLILGRDRMKNPDRGYAKTFLAQLEDCLGLAHDRGVRIVTNAGGLNPAGLANAVRALAARLGIPAQVAHVEGDDLQPRAAELGLGTPLTANAYLGAWGIVDCFERGADVVVTGRVTDASVVVGAAAAHFGWGRTDYHRLAGAVVAGHVIECGVQATGGNYAFFTEIGDLTHAGFPLAEIAADGSSVITKHHGTGGLVSVDTITAQLLYEITGARYANPDVTARMDSVELSPDGPDRVRISGVIGEPPPPTYKVSLNSIGGFRNAMTFVLTGLDIDAKADLVRRQLEAALTVKPAELQWTLARTDHPDADTEETASALLTCVARDPDPANVGRQFSSAAVELALASYPGFTATAPPGDGQVYGVFTPGYVDAGKVAHIAVHADGTRTEIPCATETLELAPAHPPALPDPLPAGPTRRVPLGLIAGARSGDKGGSANVGVWVRTDEQWRWLAHTLTVELLKELLPETAGLVVTRHVLPNLRALNFVIEAILGQGVAYQARFDPQAKGLGEWLRSRHVEIPETLL
>NC_020559.1|WP_003898670.1|1086200_1087349_-|acyl-CoA-dehydrogenase-FadE13
MNIWTTPERQQLRKTVRAFAEREILPHVDEWERIGELPRGLHRLAGAAGLLGAGFPEAVGGGGGDGADPVIICEEMHQAGAPGGVYASLFTCGIAVPHMVASGDERLIATYVRPTLAGEKIGALAITEPGGGSDVGHLRTSAVRDGDHYVINGAKTYITSGVRADYVVTAVRTGGPGAAGVSLLVVEKDTPGFEVTRKLDKMGWRSSDTAELCYTDVAVPATNLVGAENSGFTQIARAFVSERIGLAAQAYSSAQRCLDLTAQWCRDRETFGRPLISRQSVQNTLAEMARRIDVARVYAHHVVERQLAGETDLIAQVCFAKNTAVQAGEWVANQAVQLFGGMGYMAESEVERQYRDMRILGIGGGTTEILTALAAKTLGYQS
>NC_020559.1|WP_003900245.1|1084608_1086198_-|acyl-CoA-carboxylase-subunit-beta
MLQSTLDPNASAYDEAAATMSGKLDEINAELAKALAGGGPKYVDRHHARGKLTPRERIELLVDPDSPFLELSPLAAYGSNFQIGASLVTGIGAVCGVECMIVANDPTVKGGTSNPWTLRKILRANQIAFENRLPVISLVESGGADLPTQKEIFIPGGQMFRDLTRLSAAGIPTIALVFGNSTAGGAYVPGMSDHVVMIKERSKVFLAGPPLVKMATGEESDDESLGGAEMHARISGLADYFALDELDAIRIGRRIVARLNWIKQGPAPAPVTEPLFDAEELIGIVPPDLRIPFDPREVIARIVDGSEFDEFKPLYGSSLVTGWARLHGYPLGILANARGVLFSEESQKATQFIQLANRADTPLLFLHNTTGYMVGKDYEEGGMIKHGSMMINAVSNSTVPHISLLIGASYGAGHYGMCGRAYDPRFLFAWPSAKSAVMGGAQLSGVLSIVARAAAEARGQQVDEAADAAMRAAVEGQIEAESLPLVLSGMLYDDGVIDPRDTRTVLGMCLSAIANGPIKGTSNFGVFRM
>NC_020559.1|WP_003900244.1|1082599_1084603_-|acetyl/propionyl-CoA-carboxylase-subunit-alpha
MGITRVLVANRGEIARRVFATCRRLGLGTVAVYTDPDAAAPHVAEADARVRLPQTTDYLNAEAIIAAAQAAGADAVHPGYGFLSENAEFAAAVQEAGLTWVGPPVDAVRAMGSKIESKKLMAAAGVPVLEELDPDAVTTAQLPVLVKASAGGGGRGMRVVHELSALPAEVEAARREAQSAFGDPTVFCERYLPTGHHVEVQVMADTHGTVWAVGERECSIQRRHQKIIEEAPSPLVERVPGMRAKLFDAARLAASAIGYTGAGTVEFLADDSPGREGEFYFLEMNTRLQVEHPVTEETTGLDLVELQLMIADCGRLDTEPPPAQGYSIEARLYAEDPAHGWQPQAGVMHTIEVPGVRAQFDSLGQRTGIRLDSGIVDGSTVSIHYDPMLAKVVSYGATRRQAALVLADALVRARLHGLRTNRELLVNVLRHPAFLDGATDTGFFDTHGMAELSTPLADTATLRLSAIAAALADAEHNRASAGVFSSIPSGWRNLASGYQVKTYRDDADTEHRVEYRFTRTGLALPGDPVVQLVSADVDQVVLAQDGVAHGFTVARHGPDVYVDSARGPVHLVALSRFPEPSSAVEQGSLVAPMPGNVIRIGAEVGDTVTAGQPLIWLEAMKMEHTIAAPADGVLTHVSVNTGQQVEVGAILARVEAPQNGPAEGDSP
>NC_020559.1|WP_003898667.1|1081436_1082603_-|acyl-CoA-dehydrogenase
MTDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSELWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAAAGSALLLMVVSPAINGTIIAKFGTDDQKKRWLPGIADGSLTMAFAITEPDAGSNSHKITTTARRDGSDWIIKGQKVFISGIDQAQAVLVVGRSEEAKTGKLRPALFVVPTDAPGFSYTPIEMELVSPERQFQVFLDDVRLPADALVGAEDAAIAQLFAGLNPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGAHQGLAHPLAQCHIEVELAKLMTQKAATLYDHGDDFGAAEAANMAKYAAAEASSRAVDQAVQSMGGNGLTKEYGVAAMMTSARLARIAPISREMVLNFVAQTSLGLPRSY
>NC_020559.1|WP_003404949.1|1080627_1081437_-|enoyl-CoA-hydratase-family-protein
MDSPVDYAGPAACGGPFARLTLNSPHNRNALSSTLVSQLHQGLSAAEADPAVRLVVLGHTGGTFCAGADLSEAGGGGGDPYRMAVARAREMTALLRAIVESPLPVVGAINGHVRAGGFGLVGACDMVVAGPESTFALTEARIGVAPAIISLTLLPKLSPRAAARYYLTGEKFGAREAADIGLITMAADDVDAAVAALVADVGRGSPQGLAASKALTTAAVLEGFDRDAERLTEESARLFVSDEAREGMLAFLQKRPPRWVQPATMRAAD
>NC_020559.1|WP_003916757.1|1095874_1096561_+|two-component-system-response-regulator-MrpA
MRILVVDDDRAVRESLRRSLSFNGYSVELAHDGVEALDMIASDRPDALVLDVMMPRLDGLEVCRQLRGTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTKPEDAAESMAMRFSDLTLDPVTREVNRGQRRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVYVGYLRRKTEADGEPRLIHTVRGVGYVLRETPP
>NC_020559.1|WP_003911317.1|1096560_1098075_+|two-component-system-sensor-histidine-kinase-MprB
MWWFRRRDRAPLRATSSLSLRWRVMLLAMSMVAMVVVLMSFAVYAVISAALYSDIDNQLQSRAQLLIASGSLAADPGKAIEGTAYSDVNAMLVNPGQSIYTAQQPGQTLPVGAAEKAVIRGELFMSRRTTADQRVLAIRLTNGSSLLISKSLKPTEAVMNKLRWVLLIVGGIGVAVAAVAGGMVTRAGLRPVGRLTEAAERVARTDDLRPIPVFGSDELARLTEAFNLMLRALAESRERQARLVTDAGHELRTPLTSLRTNVELLMASMAPGAPRLPKQEMVDLRADVLAQIEELSTLVGDLVDLSRGDAGEVVHEPVDMADVVDRSLERVRRRRNDILFDVEVIGWQVYGDTAGLSRMALNLMDNAAKWSPPGGHVGVRLSQLDASHAELVVSDRGPGIPVQERRLVFERFYRSASARALPGSGLGLAIVKQVVLNHGGLLRIEDTDPGGQPPGTSIYVLLPGRRMPIPQLPGATAGARSTDIENSRGSANVISVESQSTRAT
>NC_020559.1|WP_003901059.1|1098118_1099513_+|serine-protease-PepD
MAKLARVVGLVQEEQPSDMTNHPRYSPPPQQPGTPGYAQGQQQTYSQQFDWRYPPSPPPQPTQYRQPYEALGGTRPGLIPGVIPTMTPPPGMVRQRPRAGMLAIGAVTIAVVSAGIGGAAASLVGFNRAPAGPSGGPVAASAAPSIPAANMPPGSVEQVAAKVVPSVVMLETDLGRQSEEGSGIILSAEGLILTNNHVIAAAAKPPLGSPPPKTTVTFSDGRTAPFTVVGADPTSDIAVVRVQGVSGLTPISLGSSSDLRVGQPVLAIGSPLGLEGTVTTGIVSALNRPVSTTGEAGNQNTVLDAIQTDAAINPGNSGGALVNMNAQLVGVNSAIATLGADSADAQSGSIGLGFAIPVDQAKRIADELISTGKASHASLGVQVTNDKDTPGAKIVEVVAGGAAANAGVPKGVVVTKVDDRPINSADALVAAVRSKAPGATVALTFQDPSGGSRTVQVTLGKAEQ
>NC_020559.1|WP_003405127.1|1099512_1100058_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein
MKVAAQCSKLGYTVAPMEQRAELVVGRALVVVVDDRTAHGDEDHSGPLVTELLTEAGFVVDGVVAVSADEVEIRNALNTAVIGGVDLVVSVGGTGVTPRDVTPEATRDILDREILGIAEAIRASGLSAGIVDAGLSRGLAGVSGSTLVVNLAGSRYAVRDGMATLNPLAAQIIGQLSSLEI
>NC_020559.1|WP_003405128.1|1100077_1100533_-|large-conductance-mechanosensitive-channel-protein-MscL
MLKGFKEFLARGNIVDLAVAVVIGTAFTALVTKFTDSIITPLINRIGVNAQSDVGILRIGIGGGQTIDLNVLLSAAINFFLIAFAVYFLVVLPYNTLRKKGEVEQPGDTQVVLLTEIRDLLAQTNGDSPGRHGGRGTPSPTDGPRASTESQ
>NC_020559.1|WP_003900248.1|1100855_1101602_+|ABC-transporter-ATP-binding-protein
MNRQPIVQLSNLSWTFREGETRRQVLDHITFDFEPGEFVALLGQSGSGKSTLLNLISGIEKPTTGDVTINGFAITQKTERDRTLFRRDQIGIVFQFFNLIPTLTVLENITLPQELAGVSQRKAAVVARDLLEKVGMADRERTFPDKLSGGEQQRVAISRALAHNPMLVLADEPTGNLDSDTGDKVLDVLLDLTRQAGKTLIMATHSPSMTQHADRVVNLQGGRLIPAVNRENQTDQPASTILLPTSYE
>NC_020559.1|WP_003898675.1|1104167_1105328_+|hypothetical-protein
MRKAGLTGVVLVLTLTLVAFWWWQRPRTNAVAADSLVGVLVDENNAGYSLATVPGAVRFPRDLGPHYDYQTEWWYYTGNLETADGRLFGYQLTFFRRALAPPGEGVAIADASSWRTTQVYMAHFAISDISNRGFYPAEKFSRQALGLAGASSEPYAVWLDDWYARESNNNSVQLFARTQNTVLDLTLTQTLPPILQGNAGLSVKGAQPGNASNYYSLVRQESRGTVSVNGDTFMVSGLSWKDHEYMTSALAPEDVGWDWFGLQFYNGTALMLFQIRQADGSVTRFSSGTFVAGDGGVIPLESSDFRIKTTDRWTSDQSGATYPIAWEIEIERIGLTLRGAALMANQELRLSRTYWEGAVALEGRYQGMPISGRGYVEMTGYVQRLS
>NC_020559.1|WP_003405136.1|1105456_1106434_-|polyprenyl-diphosphate-synthase-GrcC
MIPAVSLGDPQFTANVHDGIARITELINSELSQADEVMRDTVAHLVDAGGTPFRPLFTVLAAQLGSDPDGWEVTVAGAAIELMHLGTLCHDRVVDESDMSRKTPSDNTRWTNNFAILAGDYRFATASQLASRLDPEAFAVVAEAFAELITGQMRATRGPASHIDTIEHYLRVVHEKTGSLIAASGQLGAALSGAAEEQIRRVARLGRMIGAAFEISRDIIAISGDSATLSGADLGQAVHTLPMLYALREQTPDTSRLRELLAGPIHDDHVAEALTLLRCSPGIGKAKNVVAAYAAQAREELPYLPDRQPRRALATLIDHAVSACD
>NC_020559.1|WP_003898677.1|1106494_1107151_-|flagella-basal-body-P-ring-formation-protein-FlgA
MAESSLNPSLVSRISAFLRPDWTRTVRARRFAAAGLVMLAGVAALRSNPEDDRSEVVVAAHDLRPGTALTPGDVRLEKRSATTLPDGSQADLDAVVGSTLASPTRRGEVLTDVRLLGSRLAESTAGPDARIVPLHLADSALVDLVRVGDVVDVLAAPVTDSPAALRLLATDAIVVLVSAQQKAQAADSDRVVLVALPARLANTVAGAALGQTVTLTLH
>NC_020559.1|WP_003405142.1|1107223_1107556_-|FmdB-family-transcriptional-regulator
MPTYSYECTQCANRFDVVQAFTDDALTTCERCSGRLRKLFNAVGVVFKGTGFYRTDSRESGKKSKSQTNGSSTSESTKSSGSSGSSGSSESKASGSTEKSTSSTTAAAAV

Crispr_ID: NC_020559_7

• CRISPR_ID: NC_020559_7
• CRISPR_location: 1625752-1625836
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020559_7

Consensus_repeat	Method
GCCGCCCTTACCGCCGGCGCCGCCAGC	CRISPRCasFinder

spacers of NC_020559_7

>7.1|1625779|30|NC_020559|CRISPRCasFinder
CCCGCCGGCCCCGCCGGCGACGGTGGCGTT

CRISPR arrays and Neighbor proteins around NC_020559_7

CRISPR arrays

The CRISPR arrays of NC_020559_7

>merge|NC_020559|7|1625752-1625836|CRISPRCasFinder
CCCGCCGTTGCCGCCCTTGCCGCCGGCCCCGCCGGCCCCGCCGGCGACGGTGGCGTTCGCGCCGTTGCCGCCGGTGCCGCCGTTG

>NC_020559|7|3|1625752-1625836|CRISPRCasFinder
CCCGCCGTTGCCGCCCTTGCCGCCGGC	CCCGCCGGCCCCGCCGGCGACGGTGGCGTT
CGCGCCGTTGCCGCCGGTGCCGCCGTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_044519831.1|1611276_1612695_-|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_020559.1|WP_003407466.1|1634268_1635201_-|heme-A-synthase	unknown	unknown	gnl|CDD|224528
NC_020559.1|WP_003407437.1|1617464_1618376_-|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA	unknown	unknown	gnl|CDD|213538
NC_020559.1|WP_003407462.1|1632449_1633436_-|quinone-oxidoreductase	unknown	unknown	gnl|CDD|176189
NC_020559.1|WP_003407451.1|1621107_1623210_-|transketolase	unknown	unknown	gnl|CDD|223100
NC_020559.1|WP_003407477.1|1636094_1637036_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_020559.1|WP_003900341.1|1633455_1634319_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003900342.1|1639817_1642358_+|intein-containing-Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl|CDD|131035
NC_020559.1|WP_003898882.1|1627817_1628744_+|protoheme-IX-farnesyltransferase	unknown	unknown	gnl|CDD|235293
NC_020559.1|WP_003407433.1|1616724_1617468_-|6-phosphogluconolactonase	unknown	unknown	gnl|CDD|376480
NC_020559.1|WP_015456254.1|1612801_1615102_+|molybdopterin-guanine-dinucleotide-containing-S/N-oxide-reductase	unknown	unknown	gnl|CDD|273110
NC_020559.1|WP_009937558.1|1616134_1616248_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003902080.1|1639014_1639821_+|suf-operon-transcriptional-regulator-SufR	unknown	unknown	gnl|CDD|225222
NC_020559.1|WP_003898881.1|1616297_1616708_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003904629.1|1631156_1632422_+|PucR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225306
NC_020559.1|WP_003407479.1|1637191_1638967_-|polyprenol-phosphomannose-dependent-alpha-1,6-mannosyltransferase-MptB	unknown	unknown	gnl|CDD|274589
NC_020559.1|WP_003407447.1|1619969_1621091_-|transaldolase	unknown	unknown	gnl|CDD|235117
NC_020559.1|WP_003407443.1|1618428_1619973_-|glucose-6-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|235579
NC_020559.1|WP_003407475.1|1635312_1636098_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|272861
NC_020559.1|WP_003407422.1|1615217_1615703_-|hypothetical-protein	unknown	unknown	gnl|CDD|176862

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_044519831.1|1611276_1612695_-|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	5.05353e-30
NC_020559.1|WP_003407437.1|1617464_1618376_-|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA	gnl|CDD|213538	TIGR00534, Putative_OxPP_cycle_protein_OpcA, glucose-6-phosphate dehydrogenase assembly protein OpcA. The opcA gene is found immediately downstream of zwf, the glucose-6-phosphate dehydrogenase (G6PDH) gene, in a number of species, including Mycobacterium tuberculosis, Streptomyces coelicolor, Nostoc punctiforme, and Synechococcus sp. PCC 7942. In the latter, disruption of opcA was shown to block assembly of G6PDH into active oligomeric forms. [Protein fate, Protein folding and stabilization].	1.38424e-154
NC_020559.1|WP_003407462.1|1632449_1633436_-|quinone-oxidoreductase	gnl|CDD|176189	cd05286, QOR2, Quinone oxidoreductase (QOR). Quinone oxidoreductase (QOR) and 2-haloacrylate reductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. 2-haloacrylate reductase, a member of this subgroup, catalyzes the NADPH-dependent reduction of a carbon-carbon double bond in organohalogen compounds. Although similar to QOR, Burkholderia 2-haloacrylate reductase does not act on the quinones 1,4-benzoquinone and 1,4-naphthoquinone. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	2.18575e-173
NC_020559.1|WP_003407451.1|1621107_1623210_-|transketolase	gnl|CDD|223100	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism].	0
NC_020559.1|WP_003407477.1|1636094_1637036_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.38211e-90
NC_020559.1|WP_003900342.1|1639817_1642358_+|intein-containing-Fe-S-cluster-assembly-protein-SufB	gnl|CDD|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	1.11483e-131
NC_020559.1|WP_003898882.1|1627817_1628744_+|protoheme-IX-farnesyltransferase	gnl|CDD|235293	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional.	1.94453e-135
NC_020559.1|WP_003407433.1|1616724_1617468_-|6-phosphogluconolactonase	gnl|CDD|376480	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase.	1.17344e-94
NC_020559.1|WP_015456254.1|1612801_1615102_+|molybdopterin-guanine-dinucleotide-containing-S/N-oxide-reductase	gnl|CDD|273110	TIGR00509, Trimethylamine-N-oxide_reductase_1, molybdopterin guanine dinucleotide-containing S/N-oxide reductases. This enzyme family shares sequence similarity and a requirement for a molydenum cofactor as the only prosthetic group. The form of the cofactor is a single molybdenum atom coordinated by two molybdopterin guanine dinucleotide molecules. Members of the family include biotin sulfoxide reductase, dimethylsulfoxide reductase, and trimethylamine-N-oxide reductase, although a single member may show all those activities and related activities; it may not be possible to resolve the primary function for members of this family by sequence comparison alone. A number of similar molybdoproteins in which the N-terminal region contains a CXXXC motif and may bind an iron-sulfur cluster are excluded from this set, including formate dehydrogenases and nitrate reductases. Also excluded is the A chain of a heteromeric, anaerobic DMSO reductase, which also contains the CXXXC motif.	0
NC_020559.1|WP_003904629.1|1631156_1632422_+|PucR-family-transcriptional-regulator	gnl|CDD|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.28507e-98
NC_020559.1|WP_003902080.1|1639014_1639821_+|suf-operon-transcriptional-regulator-SufR	gnl|CDD|225222	COG2345, COG2345, Predicted transcriptional regulator [Transcription].	4.83711e-80
NC_020559.1|WP_003407466.1|1634268_1635201_-|heme-A-synthase	gnl|CDD|224528	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones].	9.53658e-61
NC_020559.1|WP_003407479.1|1637191_1638967_-|polyprenol-phosphomannose-dependent-alpha-1,6-mannosyltransferase-MptB	gnl|CDD|274589	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein. This model represents a family of hydrophobic and presumed membrane proteins found in the Actinobacteria. The genes encoding these proteins are syntenically associated with (found proximal to) genes of carotene biosynthesis ususally including phytoene synthase (crtB), phytoene dehydrogenase (crtI) and geranylgeranyl pyrophosphate synthase (ispA).	2.25454e-61
NC_020559.1|WP_003407447.1|1619969_1621091_-|transaldolase	gnl|CDD|235117	PRK03343, PRK03343, transaldolase; Validated.	0
NC_020559.1|WP_003407443.1|1618428_1619973_-|glucose-6-phosphate-dehydrogenase	gnl|CDD|235579	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated.	0
NC_020559.1|WP_003407475.1|1635312_1636098_-|ABC-transporter-permease	gnl|CDD|272861	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family. The seed members for this model are a paralogous family of Mycobacterium tuberculosis. Nearly all proteins scoring above the noise cutoff are from high-GC Gram-positive organisms. The members of this paralogous family of efflux proteins are all found in operons with ATP-binding chain partners. They are related to a putative daunorubicin resistance efflux protein of Streptomyces peucetius. This model represents a branch of a larger superfamily that also includes NodJ, a part of the NodIJ pair of nodulation-triggering signal efflux proteins. The members of this branch may all act in antibiotic resistance.	2.1257e-66
NC_020559.1|WP_003407422.1|1615217_1615703_-|hypothetical-protein	gnl|CDD|176862	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	1.36448e-06

Protein sequences

>NC_020559.1|WP_003407451.1|1621107_1623210_-|transketolase
MTTLEEISALTRPRHPDDWTEIDSAAVDTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRTMRHDPSDTHWLGRDRFVLSAGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTPGVEITTGPLGQGLASAVGMAMASRYERGLFDPDAEPGASPFDHYIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDRNQISIEDDTNIALCEDTAARYRAYGWHVQEVEGGENVVGIEEAIANAQAVTDRPSFIALRTVIGYPAPNLMDTGKAHGAALGDDEVAAVKKIVGFDPDKTFQVREDVLTHTRGLVARGKQAHERWQLEFDAWARREPERKALLDRLLAQKLPDGWDADLPHWEPGSKALATRAASGAVLSALGPKLPELWGGSADLAGSNNTTIKGADSFGPPSISTKEYTAHWYGRTLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLAALMDIDTIYVWTHDSIGLGEDGPTHQPIEHLSALRAIPRLSVVRPADANETAYAWRTILARRNGSGPVGLILTRQGVPVLDGTDAEGVARGGYVLSDAGGLQPGEEPDVILIATGSEVQLAVAAQTLLADNDILARVVSMPCLEWFEAQPYEYRDAVLPPTVSARVAVEAGVAQCWHQLVGDTGEIVSIEHYGESADHKTLFREYGFTAEAVAAAAERALDN
>NC_020559.1|WP_003407447.1|1619969_1621091_-|transaldolase
MTAQNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTNPSIFQKALSEGHTYDAQIAELAARGADVDATIRTVTTDDVRSACDVLVPQWEDSDGVDGRVSIEVDPRLAHETEKTIQQAIELWKIVDRPNLFIKIPATKAGLPAISAVLAEGISVNVTLIFSVQRYREVMDAYLTGMEKARQAGHSLSKIHSVASFFVSRVDTEIDKRLDRIGSRQALELRGQAGVANARLAYAAYREVFEDSDRYRSLKVDGARVQRPLWASTGVKNPDYSDTLYVTELVAPHTVNTMPEKTIDAVADHGVIQGDTVTGTASDAQAVFDQLGAIGIDLTDVFAVLEEEGVRKFEASWNELLQETRAHLDTAAQ
>NC_020559.1|WP_003407443.1|1618428_1619973_-|glucose-6-phosphate-dehydrogenase
MKPAHAAASWRNPLRDKRDKRLPRIAGPCGMVIFGVTGDLARKKVMPAVYDLANRGLLPPTFSLVGFARRDWSTQDFGQVVYNAVQEHCRTPFRQQNWDRLAEGFRFVPGTFDDDDAFAQLAETLEKLDAERGTGGNHAFYLAIPPKSFPVVCEQLHKSGLARPQGDRWSRVVIEKPFGHDLASARELNKAVNAVFPEEAVFRIDHYLGKETVQNILALRFANQLFDPIWNAHYVDHVQITMAEDIGLGGRAGYYDGIGAARDVIQNHLMQLLALTAMEEPVSFHPAALQAEKIKVLSATRLAEPLDQTTSRGQYAAGWQGGEKVVGLLDEEGFAEDSTTETFAAITLEVDTRRWAGVPFYLRTGKRLGRRVTEIALVFRRAPHLPFDATMTDELGTNAMVIRVQPDEGVTLRFGSKVPGTAMEVRDVNMDFSYGSAFAEDSPEAYERLILDVLLGEPSLFPVNAEVELAWEILDPALEHWAAHGTPDAYEAGTWGPESSLEMLRRTGREWRRP
>NC_020559.1|WP_003407437.1|1617464_1618376_-|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA
MIVDLPDTTTTAVNKKLDELREKIGAVAMGRVLTLIIAPDSEAMLEESIEAANDASHEHPSRIIVTMRGDPYADRPRLDAQLRVGADAGAGEFVVLRLSGPLAGHADSVVIPFLLPDIPVVAWWPDIAPAVPAQDALGKLAIRRITDATNAIDPLSAIKSRLAGYGAGDTDLAWSRITYWRALLTSAVDQPPHEPIESALVSGLKTEPALDVLAGWLASRIEGPVRRAVGELKVELVRNSETIVLSRPQEGITATLTRTGKPDALVPLARRVTGECLAEDLRRLDPDEIYCAALEGIKKVQYR
>NC_020559.1|WP_003407433.1|1616724_1617468_-|6-phosphogluconolactonase
MSSSIEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGNGIALLRYLSAQAQQIEWSKVHLFWGDERYVPEDDDERNLKQARRALLNHVDIPSNQVHPMAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLGMGPEGHINSLFPHSPAVLESTRMVVAVDDSPKPPPRRITLTLPAIQRSREVWLLVSGPGKADAVAAAIGGADPVSVPAAGAVGRQNTLWLLDRDAAAKLPS
>NC_020559.1|WP_003898881.1|1616297_1616708_-|hypothetical-protein
MTVMADRSGRPAPVRRRMKTLTQAALNADKTVEQVEDVLDGLGKTMAELNSSLSQLNSTVERLEDGLDHLEGTLHSLDDLAKRLIVLVEPVEAIVDRIDYIVSLGETVMSPLSVTEHAVRGVLDRLRNRTVHEPTN
>NC_020559.1|WP_009937558.1|1616134_1616248_-|hypothetical-protein
MFLGQATIWAGWAILCGRLPVATGLAVFVGIWFVASP
>NC_020559.1|WP_003407422.1|1615217_1615703_-|hypothetical-protein
MVGYAEPVLIERQSVVAAPAEQVWQRVVTPEGINDELRPWMTMSVPRGAKGMTVDTVPIGAPIGRAWLRLFGVLPFDYDRLSIAELEPGRRFREDSTMLSMRQWQHERTVTPEGDTKTIVRDRITFQTRAGLRFAAPLIAAGLRALFGHRHRRLQRHFAQG
>NC_020559.1|WP_015456254.1|1612801_1615102_+|molybdopterin-guanine-dinucleotide-containing-S/N-oxide-reductase
MQVYTSATHWGVFTARVHGGDIAAVAALASDTNPAPQLQNLPGAVRHRSRIANPAVRRGWLQRGPGPSSARGAEEFVEVSWDELIELLASELRRTVDRYGNEAIYGSSYGWASAGRFHHAQSQVHRFLNMLGGYTASRHSYSAGASEVIFPHIVGAALFEALAETTTWDVIVDHTALLVAFGGLPVKNTAVMPGGTTAHPDRDYVGRYRARGGRLVSVSPLRDDIAAIAGPLDDRCRWLAPVPGTDVAIMLGLAYVLATESLADRAFLGRYCTGYERFERYLLGLDDGIPKTPEWAAALSGLAAGDLRDLARRMAEHRTLITTSLSLQRIEHGEQTVWMAATLAAMLGQIGLPGGGFGHGYSSNGVGNPPLACGLPALPQGNNPVSTFIPVAAISELLQRPGQRLAYNGRLLELPDIKCVYWAGGNPFHHHQNLPRLRRALSRVDTIVVHEQYWTAMAKHADIVVPTTTSFERDDFAASKTNPTLIAMPAMVPPYANARDDYHTFSALAHRLGFGKQFTEGRSAREWLEHMYDKWSAELDFPVPSFAEFWRTGRLELPTRTGLTWLADFRADPAAHPLGTPSGRIEIFSDTVDAFALPDCAGHPTWYEPSEWLGGPRAARYPLHLIANQPRTRLHSQLDHGGASMASKIRGREPIRIHPDDAAARELTDGDIVRVFNDRGACLAGVVIDDGLRPKVVQLSTGAWFDPADPRDPDSMCVHGNPNALSNDSGTSSLAHGSTGQHVLVQIERFTGELPPVRAHEPPRLA
>NC_020559.1|WP_044519831.1|1611276_1612695_-|PE-family-protein
MSNVMVVPGMLSAAAADVASIGAALSAANGAAAPTTAGVLAAGADEVSAAIASLFSGYARDYQALSAQMARFHQQFVQALTASVGSYAAAEAANASPLQALEQQVLAAINAPTQTLLGRPLIGNGADGLPGQNGGAGGLLWGNGGNGGAGDAAHPNGGNGGDAGMFGNGGAGGAGYSPAAGTGAAGGAGGAGGAGGWLSGNGGAGGNGGTGASGADGGGGLPPVPASPGGNGGGGDAGGAAGMFGTGGAGGTGGDGGAGGAGDSPNSGANGARGGDGGNGAAGGAGGRLFGNGGAGGNGGTAGQGGDGGTALGAGGIGGDGGTGGAGGTGGTAGIGGGSSMIGGKGGTGGNGGVGGTGGASALTIGNGSSAGAGGAGGAGGTGGTGGYIESLDGKGQAGNGGNGGNGAAGGAGGGGTGAGGNGGAGGNGGDGGPSQGGGNPGFGGDGGTGGPGGVGVPDGIGGANGAQGKHG
>NC_020559.1|WP_003898882.1|1627817_1628744_+|protoheme-IX-farnesyltransferase
MNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH
>NC_020559.1|WP_003904629.1|1631156_1632422_+|PucR-family-transcriptional-regulator
MALRETSPRIHELIREAARIALNPTQEWLDEFDRAILAANPSIAADPALATVVKRSNRAHLIHFAAANLRNPGAPVPANLGPEPLRMARDLVRVGLDALALDIYRIGQNVAWRRWTDIAFGLTSDPDELHELLDVPFRTANEFVDTTLAGITTEMQLERDKLTRDVPAERRKIVQLLIDGAPISREHAEARLGYPLDRSHTAAVIWGDQAQGDHSHLDRVADAFGHAGGCPHPLVVVAGAATRWVWVKDAPGFDIDLIHEVLHDIPDARIAIGATAPGIEGFRRSHRDALTTARMIIRLESPHRVAFFTDVEMVALLTENAEGADDFIQRTLGNLESASPALKTTLLTFINQQCNASRAARLLFTHRNTLMNRLETAQRLLPRPLADTTIHVAVALEAQQWREKQTSDPPAKKESNGTKMR
>NC_020559.1|WP_003407462.1|1632449_1633436_-|quinone-oxidoreductase
MHAIEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPRELPFVIGSEVCGTVEAVGPGVTAADTAISVGDRVVSASANGAYAEFCTAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGDTVLVHAGAGGVGLILTQWATHLGVRVITTVSTAEKAKLSKDAGADVVLDYPEDAWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTLALFGAASGPVPPVDPQRLNAAGSVYLTRPSLFHFTRTGEEFSWRAAELFDAIGSEAITVAVGGRYPLADALRAHQDLEARKTVGSVVLLP
>NC_020559.1|WP_003900341.1|1633455_1634319_+|hypothetical-protein
MKLARPDVFHPRVVLAGWPQQPAGDGDDAGLVAALRHRGLHAGWLSWDDPEIVHADLVILRATRDYPARLDEFLAWTTRVANLLNSRPVVAWNVERRYLRDLMDRGVPTVPGEVYVPGEPVRLPRKGQVFVGPTIGTGTRRCSARFAAEFVAQLHAAGQAVLVQPGGSGDETVLVFLGGEPSHAFTKQADTWRQTEPDFEIWDVGAAAVAGAAAQVGVDPGELLYARAHITGGSRDPRLLELQLVDPSLGWQWLDPDIRNLAQRDFALCVQSALERLGLGPFSHRRP
>NC_020559.1|WP_003407466.1|1634268_1635201_-|heme-A-synthase
MPYDRAVSPSLRVQRVIAAIVILTQGGIAVTGAIVRVTASGLGCPTWPQCFPGSFTPVVVAEVPRVHQAVEFGNRMVTFAVVIAAALAVLVVTRARRRTEVLAYAWLMPVSTVVQAMIGGITVRTGLLWWTVAIHLLASMTMVWLAVLLYVKIGQPDDGVVHELVVSPLRALTALSALNLAAVLVTGTLVTAAGPHAGDRSPSRTVPRLKVEITTLVHMHSSLLVAYLALLIGLGFGLLAVGATRAILVRLAVLLALVATQAAVGTTQYFTGVPAALVAIHVAGAAAVTAATAALWASMGERAQPQPLQR
>NC_020559.1|WP_003407475.1|1635312_1636098_-|ABC-transporter-permease
MTQTNRPAFPAGTFSPDPRPNAVPLMLAAQFSLELKLLLRNGEQLLLTMFIPITLLVGLTLLPMGSFGHNRAATFVPVIMALAVISTAFTGQAIAVAFDRRYGALKRLGATPLPVWGIIAGKSLAVVAVVFLQAIILGAIGFALGWRPALTALTLGAGIIALGTAGFAALGLLLGGTLRAEIVLAVANLMWFVFAGFGALTLESNVIPTAFKWVARVTPSGALTEALSQAMTVSVDWFGIVVLAVWGALAALAALRWFRFT
>NC_020559.1|WP_003407477.1|1636094_1637036_-|ABC-transporter-ATP-binding-protein
MNRAPDTPEVVLRLRGVCKRYGSITAVSNLDLDVHDAEVMALLGPNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPITDNARLRARIGVMLQGGGGYPAARAGEMLDLVASYAANPLDPHWLLDTLGLTEAARTTYRRLSGGQQQRLALACALVGRPQLVFLDEPTAGMDAHARVLVWELIDALRRDGVTVVLTTHHLKEAEELADRLVIIDHGVTVAAGTPAELMRSGAKDQLRFTAPPRLDLSLLASALPEGYQATELTPGEYLVEGPVDPQVLATVTAWCAQIDVLATDMRVEQRSLEDVFLDLTGRKLRQ
>NC_020559.1|WP_003407479.1|1637191_1638967_-|polyprenol-phosphomannose-dependent-alpha-1,6-mannosyltransferase-MptB
MAARHHTLSWSIASLHGDEQAVGAPLTTTELTALARTRLFGATGTVLMAIGALGAGARPVVQDPTFGVRLLNLPSRIQTVSLTMTTTGAVMMALAWLMLGRFTLGRRRMSRGELDRTLLLWMLPLLIAPPMYSKDVYSYLAQSEIGRDGLDPYRVGPASGLGLGHVFTLSVPSLWRETPAPYGPLFLWIGRGISSLTGENIVAAVLCHRLVVLIGVTLIVWATPRLAQRCGVAEVSALWLGAANPLLIMHLVAGIHNEALMLGLMLTGVEFALRGLDMANTPRPSPETWRLGPATIRASRRPELGASPRAGASRAVKPRPEWGPLAMLLAGSILITLSSQVKLPSLLAMGFVTTVLAYRWGGNLRALLLAAAVMASLTLAIMAILGWASGLGFGWINTLGTANVVRSWMSPPTLLALGTGHVGILLGLGDHTTAVLSLTRAIGVLIITVMVCWLLLAVLRGRLHPIGGLGVALAVTVLLFPVVQPWYLLWAIIPLAAWATRPGFRVAAILATLIVGIFGPTANGDRFALFQIVDATAASAIIVILLIALTYTRLPWRPLAAEQVVTAAESASKTPATRRPTAAPDAYADST
>NC_020559.1|WP_003902080.1|1639014_1639821_+|suf-operon-transcriptional-regulator-SufR
MTSTTLPHRASLVDRSTEFCHTDVVKIPAVSTTVPAAVSDGHTRRAIVRLLLESGSITAGEIGDRLGLSAAGVRRHLDALIEAGDAEASAAAPWQQVGRGRPAKRYRLTAAGRAKLDHSYDDLASAAMRQLREIGGEEAVRTFARRRIDAILADVAPADGPDDAALEAAAERIATALSKAGYVATTTRVGGPIHGVQICQHHCPVSHVAEEFPELCETEQQAMAEVLGTHVQRLATIVNGDCACTTHVPLSPAPSPRPPATSTEGASR
>NC_020559.1|WP_003900342.1|1639817_1642358_+|intein-containing-Fe-S-cluster-assembly-protein-SufB
MTLTPEASKSVAQPPTQAPLTQEEAIASLGRYGYGWADSDVAGANAQRGLSEAVVRDISAKKNEPDWMLQSRLKALRIFDRKPIPKWGSNLDGIDFDNIKYFVRSTEKQAASWDDLPEDIRNTYDRLGIPEAEKQRLVAGVAAQYESEVVYHQIREDLEAQGVIFLDTDTGLREHPDIFKEYFGTVIPAGDNKFSALNTAVWSGGSFIYVPPGVHVDIPLQAYFRINTENMGQFERTLIIADEGSYVHYVEGCLPAGELITTADGDLRPIESIRVGDFVTGHDGRPHRVTAVQVRDLDGELFTFTPMSPANAFSVTAEHPLLAIPRDEVRVMRKERNGWKAEVNSTKLRSAEPRWIAAKDVAEGDFLIYPKPKPIPHRTVLPLEFARLAGYYLAEGHACLTNGCESLIFSFHSDEFEYVEDVRQACKSLYEKSGSVLIEEHKHSARVTVYTKAGYAAMRDNVGIGSSNKKLSDLLMRQDETFLRELVDAYVNGDGNVTRRNGAVWKRVHTTSRLWAFQLQSILARLGHYATVELRRPGGPGVIIGRNVVRKDIYQVQWTEGGRGPKQARDCGDYFAVPIKKRAVREAHEPVYNLDVENPDSYLAYGFAVHNCTAPIYKSDSLHSAVVEIIVKPHARVRYTTIQNWSNNVYNLVTKRARAEAGATMEWIDGNIGSKVTMKYPAVWMTGEHAKGEVLSVAFAGEDQHQDTGAKMLHLAPNTSSNIVSKSVARGGGRTSYRGLVQVNKGAHGSRSSVKCDALLVDTVSRSDTYPYVDIREDDVTMGHEATVSKVSENQLFYLMSRGLTEDEAMAMVVRGFVEPIAKELPMEYALELNRLIELQMEGAVG

Crispr_ID: NC_020559_8

• CRISPR_ID: NC_020559_8
• CRISPR_location: 1625920-1626022
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020559_8

Consensus_repeat	Method
GCCGCCCTTACCGCCGGCGCCGCCAGC	CRISPRCasFinder

spacers of NC_020559_8

>8.1|1625947|48|NC_020559|CRISPRCasFinder
GCCACCAACTCCATCGCCGCCGTTATCGAACGTGCCCTTGGCACCGTT

CRISPR arrays and Neighbor proteins around NC_020559_8

CRISPR arrays

The CRISPR arrays of NC_020559_8

>merge|NC_020559|8|1625920-1626022|CRISPRCasFinder
GCCGCGGCTACCGCCGTTGCCGCCGTTGCCACCAACTCCATCGCCGCCGTTATCGAACGTGCCCTTGGCACCGTTGCCGCCATCACCGCCCATGCCGCCGGCG

>NC_020559|8|4|1625920-1626022|CRISPRCasFinder
GCCGCGGCTACCGCCGTTGCCGCCGTT	GCCACCAACTCCATCGCCGCCGTTATCGAACGTGCCCTTGGCACCGTT
GCCGCCATCACCGCCCATGCCGCCGGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_044519831.1|1611276_1612695_-|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_020559.1|WP_003407466.1|1634268_1635201_-|heme-A-synthase	unknown	unknown	gnl|CDD|224528
NC_020559.1|WP_003407437.1|1617464_1618376_-|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA	unknown	unknown	gnl|CDD|213538
NC_020559.1|WP_003407462.1|1632449_1633436_-|quinone-oxidoreductase	unknown	unknown	gnl|CDD|176189
NC_020559.1|WP_003407451.1|1621107_1623210_-|transketolase	unknown	unknown	gnl|CDD|223100
NC_020559.1|WP_003407477.1|1636094_1637036_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_020559.1|WP_003900341.1|1633455_1634319_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003900342.1|1639817_1642358_+|intein-containing-Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl|CDD|131035
NC_020559.1|WP_003898882.1|1627817_1628744_+|protoheme-IX-farnesyltransferase	unknown	unknown	gnl|CDD|235293
NC_020559.1|WP_003407433.1|1616724_1617468_-|6-phosphogluconolactonase	unknown	unknown	gnl|CDD|376480
NC_020559.1|WP_015456254.1|1612801_1615102_+|molybdopterin-guanine-dinucleotide-containing-S/N-oxide-reductase	unknown	unknown	gnl|CDD|273110
NC_020559.1|WP_009937558.1|1616134_1616248_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003902080.1|1639014_1639821_+|suf-operon-transcriptional-regulator-SufR	unknown	unknown	gnl|CDD|225222
NC_020559.1|WP_003898881.1|1616297_1616708_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003904629.1|1631156_1632422_+|PucR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225306
NC_020559.1|WP_003407479.1|1637191_1638967_-|polyprenol-phosphomannose-dependent-alpha-1,6-mannosyltransferase-MptB	unknown	unknown	gnl|CDD|274589
NC_020559.1|WP_003407447.1|1619969_1621091_-|transaldolase	unknown	unknown	gnl|CDD|235117
NC_020559.1|WP_003407443.1|1618428_1619973_-|glucose-6-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|235579
NC_020559.1|WP_003407475.1|1635312_1636098_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|272861
NC_020559.1|WP_003407422.1|1615217_1615703_-|hypothetical-protein	unknown	unknown	gnl|CDD|176862

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_044519831.1|1611276_1612695_-|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	5.05353e-30
NC_020559.1|WP_003407437.1|1617464_1618376_-|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA	gnl|CDD|213538	TIGR00534, Putative_OxPP_cycle_protein_OpcA, glucose-6-phosphate dehydrogenase assembly protein OpcA. The opcA gene is found immediately downstream of zwf, the glucose-6-phosphate dehydrogenase (G6PDH) gene, in a number of species, including Mycobacterium tuberculosis, Streptomyces coelicolor, Nostoc punctiforme, and Synechococcus sp. PCC 7942. In the latter, disruption of opcA was shown to block assembly of G6PDH into active oligomeric forms. [Protein fate, Protein folding and stabilization].	1.38424e-154
NC_020559.1|WP_003407462.1|1632449_1633436_-|quinone-oxidoreductase	gnl|CDD|176189	cd05286, QOR2, Quinone oxidoreductase (QOR). Quinone oxidoreductase (QOR) and 2-haloacrylate reductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. 2-haloacrylate reductase, a member of this subgroup, catalyzes the NADPH-dependent reduction of a carbon-carbon double bond in organohalogen compounds. Although similar to QOR, Burkholderia 2-haloacrylate reductase does not act on the quinones 1,4-benzoquinone and 1,4-naphthoquinone. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	2.18575e-173
NC_020559.1|WP_003407451.1|1621107_1623210_-|transketolase	gnl|CDD|223100	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism].	0
NC_020559.1|WP_003407477.1|1636094_1637036_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.38211e-90
NC_020559.1|WP_003900342.1|1639817_1642358_+|intein-containing-Fe-S-cluster-assembly-protein-SufB	gnl|CDD|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	1.11483e-131
NC_020559.1|WP_003898882.1|1627817_1628744_+|protoheme-IX-farnesyltransferase	gnl|CDD|235293	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional.	1.94453e-135
NC_020559.1|WP_003407433.1|1616724_1617468_-|6-phosphogluconolactonase	gnl|CDD|376480	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase.	1.17344e-94
NC_020559.1|WP_015456254.1|1612801_1615102_+|molybdopterin-guanine-dinucleotide-containing-S/N-oxide-reductase	gnl|CDD|273110	TIGR00509, Trimethylamine-N-oxide_reductase_1, molybdopterin guanine dinucleotide-containing S/N-oxide reductases. This enzyme family shares sequence similarity and a requirement for a molydenum cofactor as the only prosthetic group. The form of the cofactor is a single molybdenum atom coordinated by two molybdopterin guanine dinucleotide molecules. Members of the family include biotin sulfoxide reductase, dimethylsulfoxide reductase, and trimethylamine-N-oxide reductase, although a single member may show all those activities and related activities; it may not be possible to resolve the primary function for members of this family by sequence comparison alone. A number of similar molybdoproteins in which the N-terminal region contains a CXXXC motif and may bind an iron-sulfur cluster are excluded from this set, including formate dehydrogenases and nitrate reductases. Also excluded is the A chain of a heteromeric, anaerobic DMSO reductase, which also contains the CXXXC motif.	0
NC_020559.1|WP_003904629.1|1631156_1632422_+|PucR-family-transcriptional-regulator	gnl|CDD|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.28507e-98
NC_020559.1|WP_003902080.1|1639014_1639821_+|suf-operon-transcriptional-regulator-SufR	gnl|CDD|225222	COG2345, COG2345, Predicted transcriptional regulator [Transcription].	4.83711e-80
NC_020559.1|WP_003407466.1|1634268_1635201_-|heme-A-synthase	gnl|CDD|224528	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones].	9.53658e-61
NC_020559.1|WP_003407479.1|1637191_1638967_-|polyprenol-phosphomannose-dependent-alpha-1,6-mannosyltransferase-MptB	gnl|CDD|274589	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein. This model represents a family of hydrophobic and presumed membrane proteins found in the Actinobacteria. The genes encoding these proteins are syntenically associated with (found proximal to) genes of carotene biosynthesis ususally including phytoene synthase (crtB), phytoene dehydrogenase (crtI) and geranylgeranyl pyrophosphate synthase (ispA).	2.25454e-61
NC_020559.1|WP_003407447.1|1619969_1621091_-|transaldolase	gnl|CDD|235117	PRK03343, PRK03343, transaldolase; Validated.	0
NC_020559.1|WP_003407443.1|1618428_1619973_-|glucose-6-phosphate-dehydrogenase	gnl|CDD|235579	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated.	0
NC_020559.1|WP_003407475.1|1635312_1636098_-|ABC-transporter-permease	gnl|CDD|272861	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family. The seed members for this model are a paralogous family of Mycobacterium tuberculosis. Nearly all proteins scoring above the noise cutoff are from high-GC Gram-positive organisms. The members of this paralogous family of efflux proteins are all found in operons with ATP-binding chain partners. They are related to a putative daunorubicin resistance efflux protein of Streptomyces peucetius. This model represents a branch of a larger superfamily that also includes NodJ, a part of the NodIJ pair of nodulation-triggering signal efflux proteins. The members of this branch may all act in antibiotic resistance.	2.1257e-66
NC_020559.1|WP_003407422.1|1615217_1615703_-|hypothetical-protein	gnl|CDD|176862	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	1.36448e-06

Protein sequences

>NC_020559.1|WP_003407451.1|1621107_1623210_-|transketolase
MTTLEEISALTRPRHPDDWTEIDSAAVDTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRTMRHDPSDTHWLGRDRFVLSAGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTPGVEITTGPLGQGLASAVGMAMASRYERGLFDPDAEPGASPFDHYIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDRNQISIEDDTNIALCEDTAARYRAYGWHVQEVEGGENVVGIEEAIANAQAVTDRPSFIALRTVIGYPAPNLMDTGKAHGAALGDDEVAAVKKIVGFDPDKTFQVREDVLTHTRGLVARGKQAHERWQLEFDAWARREPERKALLDRLLAQKLPDGWDADLPHWEPGSKALATRAASGAVLSALGPKLPELWGGSADLAGSNNTTIKGADSFGPPSISTKEYTAHWYGRTLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLAALMDIDTIYVWTHDSIGLGEDGPTHQPIEHLSALRAIPRLSVVRPADANETAYAWRTILARRNGSGPVGLILTRQGVPVLDGTDAEGVARGGYVLSDAGGLQPGEEPDVILIATGSEVQLAVAAQTLLADNDILARVVSMPCLEWFEAQPYEYRDAVLPPTVSARVAVEAGVAQCWHQLVGDTGEIVSIEHYGESADHKTLFREYGFTAEAVAAAAERALDN
>NC_020559.1|WP_003407447.1|1619969_1621091_-|transaldolase
MTAQNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTNPSIFQKALSEGHTYDAQIAELAARGADVDATIRTVTTDDVRSACDVLVPQWEDSDGVDGRVSIEVDPRLAHETEKTIQQAIELWKIVDRPNLFIKIPATKAGLPAISAVLAEGISVNVTLIFSVQRYREVMDAYLTGMEKARQAGHSLSKIHSVASFFVSRVDTEIDKRLDRIGSRQALELRGQAGVANARLAYAAYREVFEDSDRYRSLKVDGARVQRPLWASTGVKNPDYSDTLYVTELVAPHTVNTMPEKTIDAVADHGVIQGDTVTGTASDAQAVFDQLGAIGIDLTDVFAVLEEEGVRKFEASWNELLQETRAHLDTAAQ
>NC_020559.1|WP_003407443.1|1618428_1619973_-|glucose-6-phosphate-dehydrogenase
MKPAHAAASWRNPLRDKRDKRLPRIAGPCGMVIFGVTGDLARKKVMPAVYDLANRGLLPPTFSLVGFARRDWSTQDFGQVVYNAVQEHCRTPFRQQNWDRLAEGFRFVPGTFDDDDAFAQLAETLEKLDAERGTGGNHAFYLAIPPKSFPVVCEQLHKSGLARPQGDRWSRVVIEKPFGHDLASARELNKAVNAVFPEEAVFRIDHYLGKETVQNILALRFANQLFDPIWNAHYVDHVQITMAEDIGLGGRAGYYDGIGAARDVIQNHLMQLLALTAMEEPVSFHPAALQAEKIKVLSATRLAEPLDQTTSRGQYAAGWQGGEKVVGLLDEEGFAEDSTTETFAAITLEVDTRRWAGVPFYLRTGKRLGRRVTEIALVFRRAPHLPFDATMTDELGTNAMVIRVQPDEGVTLRFGSKVPGTAMEVRDVNMDFSYGSAFAEDSPEAYERLILDVLLGEPSLFPVNAEVELAWEILDPALEHWAAHGTPDAYEAGTWGPESSLEMLRRTGREWRRP
>NC_020559.1|WP_003407437.1|1617464_1618376_-|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA
MIVDLPDTTTTAVNKKLDELREKIGAVAMGRVLTLIIAPDSEAMLEESIEAANDASHEHPSRIIVTMRGDPYADRPRLDAQLRVGADAGAGEFVVLRLSGPLAGHADSVVIPFLLPDIPVVAWWPDIAPAVPAQDALGKLAIRRITDATNAIDPLSAIKSRLAGYGAGDTDLAWSRITYWRALLTSAVDQPPHEPIESALVSGLKTEPALDVLAGWLASRIEGPVRRAVGELKVELVRNSETIVLSRPQEGITATLTRTGKPDALVPLARRVTGECLAEDLRRLDPDEIYCAALEGIKKVQYR
>NC_020559.1|WP_003407433.1|1616724_1617468_-|6-phosphogluconolactonase
MSSSIEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGNGIALLRYLSAQAQQIEWSKVHLFWGDERYVPEDDDERNLKQARRALLNHVDIPSNQVHPMAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLGMGPEGHINSLFPHSPAVLESTRMVVAVDDSPKPPPRRITLTLPAIQRSREVWLLVSGPGKADAVAAAIGGADPVSVPAAGAVGRQNTLWLLDRDAAAKLPS
>NC_020559.1|WP_003898881.1|1616297_1616708_-|hypothetical-protein
MTVMADRSGRPAPVRRRMKTLTQAALNADKTVEQVEDVLDGLGKTMAELNSSLSQLNSTVERLEDGLDHLEGTLHSLDDLAKRLIVLVEPVEAIVDRIDYIVSLGETVMSPLSVTEHAVRGVLDRLRNRTVHEPTN
>NC_020559.1|WP_009937558.1|1616134_1616248_-|hypothetical-protein
MFLGQATIWAGWAILCGRLPVATGLAVFVGIWFVASP
>NC_020559.1|WP_003407422.1|1615217_1615703_-|hypothetical-protein
MVGYAEPVLIERQSVVAAPAEQVWQRVVTPEGINDELRPWMTMSVPRGAKGMTVDTVPIGAPIGRAWLRLFGVLPFDYDRLSIAELEPGRRFREDSTMLSMRQWQHERTVTPEGDTKTIVRDRITFQTRAGLRFAAPLIAAGLRALFGHRHRRLQRHFAQG
>NC_020559.1|WP_015456254.1|1612801_1615102_+|molybdopterin-guanine-dinucleotide-containing-S/N-oxide-reductase
MQVYTSATHWGVFTARVHGGDIAAVAALASDTNPAPQLQNLPGAVRHRSRIANPAVRRGWLQRGPGPSSARGAEEFVEVSWDELIELLASELRRTVDRYGNEAIYGSSYGWASAGRFHHAQSQVHRFLNMLGGYTASRHSYSAGASEVIFPHIVGAALFEALAETTTWDVIVDHTALLVAFGGLPVKNTAVMPGGTTAHPDRDYVGRYRARGGRLVSVSPLRDDIAAIAGPLDDRCRWLAPVPGTDVAIMLGLAYVLATESLADRAFLGRYCTGYERFERYLLGLDDGIPKTPEWAAALSGLAAGDLRDLARRMAEHRTLITTSLSLQRIEHGEQTVWMAATLAAMLGQIGLPGGGFGHGYSSNGVGNPPLACGLPALPQGNNPVSTFIPVAAISELLQRPGQRLAYNGRLLELPDIKCVYWAGGNPFHHHQNLPRLRRALSRVDTIVVHEQYWTAMAKHADIVVPTTTSFERDDFAASKTNPTLIAMPAMVPPYANARDDYHTFSALAHRLGFGKQFTEGRSAREWLEHMYDKWSAELDFPVPSFAEFWRTGRLELPTRTGLTWLADFRADPAAHPLGTPSGRIEIFSDTVDAFALPDCAGHPTWYEPSEWLGGPRAARYPLHLIANQPRTRLHSQLDHGGASMASKIRGREPIRIHPDDAAARELTDGDIVRVFNDRGACLAGVVIDDGLRPKVVQLSTGAWFDPADPRDPDSMCVHGNPNALSNDSGTSSLAHGSTGQHVLVQIERFTGELPPVRAHEPPRLA
>NC_020559.1|WP_044519831.1|1611276_1612695_-|PE-family-protein
MSNVMVVPGMLSAAAADVASIGAALSAANGAAAPTTAGVLAAGADEVSAAIASLFSGYARDYQALSAQMARFHQQFVQALTASVGSYAAAEAANASPLQALEQQVLAAINAPTQTLLGRPLIGNGADGLPGQNGGAGGLLWGNGGNGGAGDAAHPNGGNGGDAGMFGNGGAGGAGYSPAAGTGAAGGAGGAGGAGGWLSGNGGAGGNGGTGASGADGGGGLPPVPASPGGNGGGGDAGGAAGMFGTGGAGGTGGDGGAGGAGDSPNSGANGARGGDGGNGAAGGAGGRLFGNGGAGGNGGTAGQGGDGGTALGAGGIGGDGGTGGAGGTGGTAGIGGGSSMIGGKGGTGGNGGVGGTGGASALTIGNGSSAGAGGAGGAGGTGGTGGYIESLDGKGQAGNGGNGGNGAAGGAGGGGTGAGGNGGAGGNGGDGGPSQGGGNPGFGGDGGTGGPGGVGVPDGIGGANGAQGKHG
>NC_020559.1|WP_003898882.1|1627817_1628744_+|protoheme-IX-farnesyltransferase
MNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH
>NC_020559.1|WP_003904629.1|1631156_1632422_+|PucR-family-transcriptional-regulator
MALRETSPRIHELIREAARIALNPTQEWLDEFDRAILAANPSIAADPALATVVKRSNRAHLIHFAAANLRNPGAPVPANLGPEPLRMARDLVRVGLDALALDIYRIGQNVAWRRWTDIAFGLTSDPDELHELLDVPFRTANEFVDTTLAGITTEMQLERDKLTRDVPAERRKIVQLLIDGAPISREHAEARLGYPLDRSHTAAVIWGDQAQGDHSHLDRVADAFGHAGGCPHPLVVVAGAATRWVWVKDAPGFDIDLIHEVLHDIPDARIAIGATAPGIEGFRRSHRDALTTARMIIRLESPHRVAFFTDVEMVALLTENAEGADDFIQRTLGNLESASPALKTTLLTFINQQCNASRAARLLFTHRNTLMNRLETAQRLLPRPLADTTIHVAVALEAQQWREKQTSDPPAKKESNGTKMR
>NC_020559.1|WP_003407462.1|1632449_1633436_-|quinone-oxidoreductase
MHAIEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPRELPFVIGSEVCGTVEAVGPGVTAADTAISVGDRVVSASANGAYAEFCTAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGDTVLVHAGAGGVGLILTQWATHLGVRVITTVSTAEKAKLSKDAGADVVLDYPEDAWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTLALFGAASGPVPPVDPQRLNAAGSVYLTRPSLFHFTRTGEEFSWRAAELFDAIGSEAITVAVGGRYPLADALRAHQDLEARKTVGSVVLLP
>NC_020559.1|WP_003900341.1|1633455_1634319_+|hypothetical-protein
MKLARPDVFHPRVVLAGWPQQPAGDGDDAGLVAALRHRGLHAGWLSWDDPEIVHADLVILRATRDYPARLDEFLAWTTRVANLLNSRPVVAWNVERRYLRDLMDRGVPTVPGEVYVPGEPVRLPRKGQVFVGPTIGTGTRRCSARFAAEFVAQLHAAGQAVLVQPGGSGDETVLVFLGGEPSHAFTKQADTWRQTEPDFEIWDVGAAAVAGAAAQVGVDPGELLYARAHITGGSRDPRLLELQLVDPSLGWQWLDPDIRNLAQRDFALCVQSALERLGLGPFSHRRP
>NC_020559.1|WP_003407466.1|1634268_1635201_-|heme-A-synthase
MPYDRAVSPSLRVQRVIAAIVILTQGGIAVTGAIVRVTASGLGCPTWPQCFPGSFTPVVVAEVPRVHQAVEFGNRMVTFAVVIAAALAVLVVTRARRRTEVLAYAWLMPVSTVVQAMIGGITVRTGLLWWTVAIHLLASMTMVWLAVLLYVKIGQPDDGVVHELVVSPLRALTALSALNLAAVLVTGTLVTAAGPHAGDRSPSRTVPRLKVEITTLVHMHSSLLVAYLALLIGLGFGLLAVGATRAILVRLAVLLALVATQAAVGTTQYFTGVPAALVAIHVAGAAAVTAATAALWASMGERAQPQPLQR
>NC_020559.1|WP_003407475.1|1635312_1636098_-|ABC-transporter-permease
MTQTNRPAFPAGTFSPDPRPNAVPLMLAAQFSLELKLLLRNGEQLLLTMFIPITLLVGLTLLPMGSFGHNRAATFVPVIMALAVISTAFTGQAIAVAFDRRYGALKRLGATPLPVWGIIAGKSLAVVAVVFLQAIILGAIGFALGWRPALTALTLGAGIIALGTAGFAALGLLLGGTLRAEIVLAVANLMWFVFAGFGALTLESNVIPTAFKWVARVTPSGALTEALSQAMTVSVDWFGIVVLAVWGALAALAALRWFRFT
>NC_020559.1|WP_003407477.1|1636094_1637036_-|ABC-transporter-ATP-binding-protein
MNRAPDTPEVVLRLRGVCKRYGSITAVSNLDLDVHDAEVMALLGPNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPITDNARLRARIGVMLQGGGGYPAARAGEMLDLVASYAANPLDPHWLLDTLGLTEAARTTYRRLSGGQQQRLALACALVGRPQLVFLDEPTAGMDAHARVLVWELIDALRRDGVTVVLTTHHLKEAEELADRLVIIDHGVTVAAGTPAELMRSGAKDQLRFTAPPRLDLSLLASALPEGYQATELTPGEYLVEGPVDPQVLATVTAWCAQIDVLATDMRVEQRSLEDVFLDLTGRKLRQ
>NC_020559.1|WP_003407479.1|1637191_1638967_-|polyprenol-phosphomannose-dependent-alpha-1,6-mannosyltransferase-MptB
MAARHHTLSWSIASLHGDEQAVGAPLTTTELTALARTRLFGATGTVLMAIGALGAGARPVVQDPTFGVRLLNLPSRIQTVSLTMTTTGAVMMALAWLMLGRFTLGRRRMSRGELDRTLLLWMLPLLIAPPMYSKDVYSYLAQSEIGRDGLDPYRVGPASGLGLGHVFTLSVPSLWRETPAPYGPLFLWIGRGISSLTGENIVAAVLCHRLVVLIGVTLIVWATPRLAQRCGVAEVSALWLGAANPLLIMHLVAGIHNEALMLGLMLTGVEFALRGLDMANTPRPSPETWRLGPATIRASRRPELGASPRAGASRAVKPRPEWGPLAMLLAGSILITLSSQVKLPSLLAMGFVTTVLAYRWGGNLRALLLAAAVMASLTLAIMAILGWASGLGFGWINTLGTANVVRSWMSPPTLLALGTGHVGILLGLGDHTTAVLSLTRAIGVLIITVMVCWLLLAVLRGRLHPIGGLGVALAVTVLLFPVVQPWYLLWAIIPLAAWATRPGFRVAAILATLIVGIFGPTANGDRFALFQIVDATAASAIIVILLIALTYTRLPWRPLAAEQVVTAAESASKTPATRRPTAAPDAYADST
>NC_020559.1|WP_003902080.1|1639014_1639821_+|suf-operon-transcriptional-regulator-SufR
MTSTTLPHRASLVDRSTEFCHTDVVKIPAVSTTVPAAVSDGHTRRAIVRLLLESGSITAGEIGDRLGLSAAGVRRHLDALIEAGDAEASAAAPWQQVGRGRPAKRYRLTAAGRAKLDHSYDDLASAAMRQLREIGGEEAVRTFARRRIDAILADVAPADGPDDAALEAAAERIATALSKAGYVATTTRVGGPIHGVQICQHHCPVSHVAEEFPELCETEQQAMAEVLGTHVQRLATIVNGDCACTTHVPLSPAPSPRPPATSTEGASR
>NC_020559.1|WP_003900342.1|1639817_1642358_+|intein-containing-Fe-S-cluster-assembly-protein-SufB
MTLTPEASKSVAQPPTQAPLTQEEAIASLGRYGYGWADSDVAGANAQRGLSEAVVRDISAKKNEPDWMLQSRLKALRIFDRKPIPKWGSNLDGIDFDNIKYFVRSTEKQAASWDDLPEDIRNTYDRLGIPEAEKQRLVAGVAAQYESEVVYHQIREDLEAQGVIFLDTDTGLREHPDIFKEYFGTVIPAGDNKFSALNTAVWSGGSFIYVPPGVHVDIPLQAYFRINTENMGQFERTLIIADEGSYVHYVEGCLPAGELITTADGDLRPIESIRVGDFVTGHDGRPHRVTAVQVRDLDGELFTFTPMSPANAFSVTAEHPLLAIPRDEVRVMRKERNGWKAEVNSTKLRSAEPRWIAAKDVAEGDFLIYPKPKPIPHRTVLPLEFARLAGYYLAEGHACLTNGCESLIFSFHSDEFEYVEDVRQACKSLYEKSGSVLIEEHKHSARVTVYTKAGYAAMRDNVGIGSSNKKLSDLLMRQDETFLRELVDAYVNGDGNVTRRNGAVWKRVHTTSRLWAFQLQSILARLGHYATVELRRPGGPGVIIGRNVVRKDIYQVQWTEGGRGPKQARDCGDYFAVPIKKRAVREAHEPVYNLDVENPDSYLAYGFAVHNCTAPIYKSDSLHSAVVEIIVKPHARVRYTTIQNWSNNVYNLVTKRARAEAGATMEWIDGNIGSKVTMKYPAVWMTGEHAKGEVLSVAFAGEDQHQDTGAKMLHLAPNTSSNIVSKSVARGGGRTSYRGLVQVNKGAHGSRSSVKCDALLVDTVSRSDTYPYVDIREDDVTMGHEATVSKVSENQLFYLMSRGLTEDEAMAMVVRGFVEPIAKELPMEYALELNRLIELQMEGAVG

Crispr_ID: NC_020559_9

• CRISPR_ID: NC_020559_9
• CRISPR_location: 1626133-1626474
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of NC_020559_9

Consensus_repeat	Method
GCCGCCCTTACCGCCGGCGCCGCCAGC	CRISPRCasFinder

spacers of NC_020559_9

>9.1|1626160|39|NC_020559|CRISPRCasFinder
CGCGCCTGCCCCCAGGCCGTTAAGGCCGGTGGCGCCGGT
>9.2|1626226|39|NC_020559|CRISPRCasFinder
ACCGCCGGCGCCGCCAGCACCGCCGTCGCCTGCTTGGGC
>9.3|1626292|57|NC_020559|CRISPRCasFinder
GCCGCCAGCTCCGCCGCCACCGCCGTTAGGGTCGCCGCCAGAAGGCGGGGCACCGGG
>9.4|1626376|18|NC_020559|CRISPRCasFinder
GCCGCCATTGCCGACCAG
>9.5|1626421|27|NC_020559|CRISPRCasFinder
GCCGGCCAGCCAGCCACCCCGCCCCCC

CRISPR arrays and Neighbor proteins around NC_020559_9

CRISPR arrays

The CRISPR arrays of NC_020559_9

>merge|NC_020559|9|1626133-1626474|CRISPRCasFinder
GCCGCCCTTGCCGCCGTCGGTGCCATCCGCGCCTGCCCCCAGGCCGTTAAGGCCGGTGGCGCCGGTGGCGCCGTTGCCGCCGTTGCCGCCCTTACCGCCGGCGCCGCCAGCACCGCCGTCGCCTGCTTGGGCTCCGCCGTCGCCGCCCTTACCGCCAGCGCCGCCAGCTCCGCCGCCACCGCCGTTAGGGTCGCCGCCAGAAGGCGGGGCACCGGGGGCGCCGTTGCCGCCGGCACCTCCGGCGCCGCCATTGCCGACCAGCCCGCCGGCCCCGCCGGCCCCGCCGGCGCCGGCCAGCCAGCCACCCCGCCCCCCGGCGCCGCCATCGCCGGCGTCGCCGCC

>NC_020559|9|5|1626133-1626474|CRISPRCasFinder
GCCGCCCTTGCCGCCGTCGGTGCCATC	CGCGCCTGCCCCCAGGCCGTTAAGGCCGGTGGCGCCGGT
GGCGCCGTTGCCGCCGTTGCCGCCCTT	ACCGCCGGCGCCGCCAGCACCGCCGTCGCCTGCTTGGGC
TCCGCCGTCGCCGCCCTTACCGCCAGC	GCCGCCAGCTCCGCCGCCACCGCCGTTAGGGTCGCCGCCAGAAGGCGGGGCACCGGG
GGCGCCGTTGCCGCCGGCACCTCCGGC	GCCGCCATTGCCGACCAG
CCCGCCGGCCCCGCCGGCCCCGCCGGC	GCCGGCCAGCCAGCCACCCCGCCCCCC
GGCGCCGCCATCGCCGGCGTCGCCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_044519831.1|1611276_1612695_-|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_020559.1|WP_003407466.1|1634268_1635201_-|heme-A-synthase	unknown	unknown	gnl|CDD|224528
NC_020559.1|WP_003407437.1|1617464_1618376_-|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA	unknown	unknown	gnl|CDD|213538
NC_020559.1|WP_003407462.1|1632449_1633436_-|quinone-oxidoreductase	unknown	unknown	gnl|CDD|176189
NC_020559.1|WP_003407451.1|1621107_1623210_-|transketolase	unknown	unknown	gnl|CDD|223100
NC_020559.1|WP_003407477.1|1636094_1637036_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_020559.1|WP_003900341.1|1633455_1634319_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003900342.1|1639817_1642358_+|intein-containing-Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl|CDD|131035
NC_020559.1|WP_003898882.1|1627817_1628744_+|protoheme-IX-farnesyltransferase	unknown	unknown	gnl|CDD|235293
NC_020559.1|WP_003407433.1|1616724_1617468_-|6-phosphogluconolactonase	unknown	unknown	gnl|CDD|376480
NC_020559.1|WP_015456254.1|1612801_1615102_+|molybdopterin-guanine-dinucleotide-containing-S/N-oxide-reductase	unknown	unknown	gnl|CDD|273110
NC_020559.1|WP_009937558.1|1616134_1616248_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003902080.1|1639014_1639821_+|suf-operon-transcriptional-regulator-SufR	unknown	unknown	gnl|CDD|225222
NC_020559.1|WP_003898881.1|1616297_1616708_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003904629.1|1631156_1632422_+|PucR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225306
NC_020559.1|WP_003407479.1|1637191_1638967_-|polyprenol-phosphomannose-dependent-alpha-1,6-mannosyltransferase-MptB	unknown	unknown	gnl|CDD|274589
NC_020559.1|WP_003407447.1|1619969_1621091_-|transaldolase	unknown	unknown	gnl|CDD|235117
NC_020559.1|WP_003407443.1|1618428_1619973_-|glucose-6-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|235579
NC_020559.1|WP_003407475.1|1635312_1636098_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|272861
NC_020559.1|WP_003407422.1|1615217_1615703_-|hypothetical-protein	unknown	unknown	gnl|CDD|176862

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_044519831.1|1611276_1612695_-|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	5.05353e-30
NC_020559.1|WP_003407437.1|1617464_1618376_-|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA	gnl|CDD|213538	TIGR00534, Putative_OxPP_cycle_protein_OpcA, glucose-6-phosphate dehydrogenase assembly protein OpcA. The opcA gene is found immediately downstream of zwf, the glucose-6-phosphate dehydrogenase (G6PDH) gene, in a number of species, including Mycobacterium tuberculosis, Streptomyces coelicolor, Nostoc punctiforme, and Synechococcus sp. PCC 7942. In the latter, disruption of opcA was shown to block assembly of G6PDH into active oligomeric forms. [Protein fate, Protein folding and stabilization].	1.38424e-154
NC_020559.1|WP_003407462.1|1632449_1633436_-|quinone-oxidoreductase	gnl|CDD|176189	cd05286, QOR2, Quinone oxidoreductase (QOR). Quinone oxidoreductase (QOR) and 2-haloacrylate reductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. 2-haloacrylate reductase, a member of this subgroup, catalyzes the NADPH-dependent reduction of a carbon-carbon double bond in organohalogen compounds. Although similar to QOR, Burkholderia 2-haloacrylate reductase does not act on the quinones 1,4-benzoquinone and 1,4-naphthoquinone. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	2.18575e-173
NC_020559.1|WP_003407451.1|1621107_1623210_-|transketolase	gnl|CDD|223100	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism].	0
NC_020559.1|WP_003407477.1|1636094_1637036_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.38211e-90
NC_020559.1|WP_003900342.1|1639817_1642358_+|intein-containing-Fe-S-cluster-assembly-protein-SufB	gnl|CDD|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	1.11483e-131
NC_020559.1|WP_003898882.1|1627817_1628744_+|protoheme-IX-farnesyltransferase	gnl|CDD|235293	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional.	1.94453e-135
NC_020559.1|WP_003407433.1|1616724_1617468_-|6-phosphogluconolactonase	gnl|CDD|376480	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase.	1.17344e-94
NC_020559.1|WP_015456254.1|1612801_1615102_+|molybdopterin-guanine-dinucleotide-containing-S/N-oxide-reductase	gnl|CDD|273110	TIGR00509, Trimethylamine-N-oxide_reductase_1, molybdopterin guanine dinucleotide-containing S/N-oxide reductases. This enzyme family shares sequence similarity and a requirement for a molydenum cofactor as the only prosthetic group. The form of the cofactor is a single molybdenum atom coordinated by two molybdopterin guanine dinucleotide molecules. Members of the family include biotin sulfoxide reductase, dimethylsulfoxide reductase, and trimethylamine-N-oxide reductase, although a single member may show all those activities and related activities; it may not be possible to resolve the primary function for members of this family by sequence comparison alone. A number of similar molybdoproteins in which the N-terminal region contains a CXXXC motif and may bind an iron-sulfur cluster are excluded from this set, including formate dehydrogenases and nitrate reductases. Also excluded is the A chain of a heteromeric, anaerobic DMSO reductase, which also contains the CXXXC motif.	0
NC_020559.1|WP_003904629.1|1631156_1632422_+|PucR-family-transcriptional-regulator	gnl|CDD|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.28507e-98
NC_020559.1|WP_003902080.1|1639014_1639821_+|suf-operon-transcriptional-regulator-SufR	gnl|CDD|225222	COG2345, COG2345, Predicted transcriptional regulator [Transcription].	4.83711e-80
NC_020559.1|WP_003407466.1|1634268_1635201_-|heme-A-synthase	gnl|CDD|224528	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones].	9.53658e-61
NC_020559.1|WP_003407479.1|1637191_1638967_-|polyprenol-phosphomannose-dependent-alpha-1,6-mannosyltransferase-MptB	gnl|CDD|274589	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein. This model represents a family of hydrophobic and presumed membrane proteins found in the Actinobacteria. The genes encoding these proteins are syntenically associated with (found proximal to) genes of carotene biosynthesis ususally including phytoene synthase (crtB), phytoene dehydrogenase (crtI) and geranylgeranyl pyrophosphate synthase (ispA).	2.25454e-61
NC_020559.1|WP_003407447.1|1619969_1621091_-|transaldolase	gnl|CDD|235117	PRK03343, PRK03343, transaldolase; Validated.	0
NC_020559.1|WP_003407443.1|1618428_1619973_-|glucose-6-phosphate-dehydrogenase	gnl|CDD|235579	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated.	0
NC_020559.1|WP_003407475.1|1635312_1636098_-|ABC-transporter-permease	gnl|CDD|272861	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family. The seed members for this model are a paralogous family of Mycobacterium tuberculosis. Nearly all proteins scoring above the noise cutoff are from high-GC Gram-positive organisms. The members of this paralogous family of efflux proteins are all found in operons with ATP-binding chain partners. They are related to a putative daunorubicin resistance efflux protein of Streptomyces peucetius. This model represents a branch of a larger superfamily that also includes NodJ, a part of the NodIJ pair of nodulation-triggering signal efflux proteins. The members of this branch may all act in antibiotic resistance.	2.1257e-66
NC_020559.1|WP_003407422.1|1615217_1615703_-|hypothetical-protein	gnl|CDD|176862	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	1.36448e-06

Protein sequences

>NC_020559.1|WP_003407451.1|1621107_1623210_-|transketolase
MTTLEEISALTRPRHPDDWTEIDSAAVDTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRTMRHDPSDTHWLGRDRFVLSAGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTPGVEITTGPLGQGLASAVGMAMASRYERGLFDPDAEPGASPFDHYIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDRNQISIEDDTNIALCEDTAARYRAYGWHVQEVEGGENVVGIEEAIANAQAVTDRPSFIALRTVIGYPAPNLMDTGKAHGAALGDDEVAAVKKIVGFDPDKTFQVREDVLTHTRGLVARGKQAHERWQLEFDAWARREPERKALLDRLLAQKLPDGWDADLPHWEPGSKALATRAASGAVLSALGPKLPELWGGSADLAGSNNTTIKGADSFGPPSISTKEYTAHWYGRTLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLAALMDIDTIYVWTHDSIGLGEDGPTHQPIEHLSALRAIPRLSVVRPADANETAYAWRTILARRNGSGPVGLILTRQGVPVLDGTDAEGVARGGYVLSDAGGLQPGEEPDVILIATGSEVQLAVAAQTLLADNDILARVVSMPCLEWFEAQPYEYRDAVLPPTVSARVAVEAGVAQCWHQLVGDTGEIVSIEHYGESADHKTLFREYGFTAEAVAAAAERALDN
>NC_020559.1|WP_003407447.1|1619969_1621091_-|transaldolase
MTAQNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTNPSIFQKALSEGHTYDAQIAELAARGADVDATIRTVTTDDVRSACDVLVPQWEDSDGVDGRVSIEVDPRLAHETEKTIQQAIELWKIVDRPNLFIKIPATKAGLPAISAVLAEGISVNVTLIFSVQRYREVMDAYLTGMEKARQAGHSLSKIHSVASFFVSRVDTEIDKRLDRIGSRQALELRGQAGVANARLAYAAYREVFEDSDRYRSLKVDGARVQRPLWASTGVKNPDYSDTLYVTELVAPHTVNTMPEKTIDAVADHGVIQGDTVTGTASDAQAVFDQLGAIGIDLTDVFAVLEEEGVRKFEASWNELLQETRAHLDTAAQ
>NC_020559.1|WP_003407443.1|1618428_1619973_-|glucose-6-phosphate-dehydrogenase
MKPAHAAASWRNPLRDKRDKRLPRIAGPCGMVIFGVTGDLARKKVMPAVYDLANRGLLPPTFSLVGFARRDWSTQDFGQVVYNAVQEHCRTPFRQQNWDRLAEGFRFVPGTFDDDDAFAQLAETLEKLDAERGTGGNHAFYLAIPPKSFPVVCEQLHKSGLARPQGDRWSRVVIEKPFGHDLASARELNKAVNAVFPEEAVFRIDHYLGKETVQNILALRFANQLFDPIWNAHYVDHVQITMAEDIGLGGRAGYYDGIGAARDVIQNHLMQLLALTAMEEPVSFHPAALQAEKIKVLSATRLAEPLDQTTSRGQYAAGWQGGEKVVGLLDEEGFAEDSTTETFAAITLEVDTRRWAGVPFYLRTGKRLGRRVTEIALVFRRAPHLPFDATMTDELGTNAMVIRVQPDEGVTLRFGSKVPGTAMEVRDVNMDFSYGSAFAEDSPEAYERLILDVLLGEPSLFPVNAEVELAWEILDPALEHWAAHGTPDAYEAGTWGPESSLEMLRRTGREWRRP
>NC_020559.1|WP_003407437.1|1617464_1618376_-|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA
MIVDLPDTTTTAVNKKLDELREKIGAVAMGRVLTLIIAPDSEAMLEESIEAANDASHEHPSRIIVTMRGDPYADRPRLDAQLRVGADAGAGEFVVLRLSGPLAGHADSVVIPFLLPDIPVVAWWPDIAPAVPAQDALGKLAIRRITDATNAIDPLSAIKSRLAGYGAGDTDLAWSRITYWRALLTSAVDQPPHEPIESALVSGLKTEPALDVLAGWLASRIEGPVRRAVGELKVELVRNSETIVLSRPQEGITATLTRTGKPDALVPLARRVTGECLAEDLRRLDPDEIYCAALEGIKKVQYR
>NC_020559.1|WP_003407433.1|1616724_1617468_-|6-phosphogluconolactonase
MSSSIEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGNGIALLRYLSAQAQQIEWSKVHLFWGDERYVPEDDDERNLKQARRALLNHVDIPSNQVHPMAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLGMGPEGHINSLFPHSPAVLESTRMVVAVDDSPKPPPRRITLTLPAIQRSREVWLLVSGPGKADAVAAAIGGADPVSVPAAGAVGRQNTLWLLDRDAAAKLPS
>NC_020559.1|WP_003898881.1|1616297_1616708_-|hypothetical-protein
MTVMADRSGRPAPVRRRMKTLTQAALNADKTVEQVEDVLDGLGKTMAELNSSLSQLNSTVERLEDGLDHLEGTLHSLDDLAKRLIVLVEPVEAIVDRIDYIVSLGETVMSPLSVTEHAVRGVLDRLRNRTVHEPTN
>NC_020559.1|WP_009937558.1|1616134_1616248_-|hypothetical-protein
MFLGQATIWAGWAILCGRLPVATGLAVFVGIWFVASP
>NC_020559.1|WP_003407422.1|1615217_1615703_-|hypothetical-protein
MVGYAEPVLIERQSVVAAPAEQVWQRVVTPEGINDELRPWMTMSVPRGAKGMTVDTVPIGAPIGRAWLRLFGVLPFDYDRLSIAELEPGRRFREDSTMLSMRQWQHERTVTPEGDTKTIVRDRITFQTRAGLRFAAPLIAAGLRALFGHRHRRLQRHFAQG
>NC_020559.1|WP_015456254.1|1612801_1615102_+|molybdopterin-guanine-dinucleotide-containing-S/N-oxide-reductase
MQVYTSATHWGVFTARVHGGDIAAVAALASDTNPAPQLQNLPGAVRHRSRIANPAVRRGWLQRGPGPSSARGAEEFVEVSWDELIELLASELRRTVDRYGNEAIYGSSYGWASAGRFHHAQSQVHRFLNMLGGYTASRHSYSAGASEVIFPHIVGAALFEALAETTTWDVIVDHTALLVAFGGLPVKNTAVMPGGTTAHPDRDYVGRYRARGGRLVSVSPLRDDIAAIAGPLDDRCRWLAPVPGTDVAIMLGLAYVLATESLADRAFLGRYCTGYERFERYLLGLDDGIPKTPEWAAALSGLAAGDLRDLARRMAEHRTLITTSLSLQRIEHGEQTVWMAATLAAMLGQIGLPGGGFGHGYSSNGVGNPPLACGLPALPQGNNPVSTFIPVAAISELLQRPGQRLAYNGRLLELPDIKCVYWAGGNPFHHHQNLPRLRRALSRVDTIVVHEQYWTAMAKHADIVVPTTTSFERDDFAASKTNPTLIAMPAMVPPYANARDDYHTFSALAHRLGFGKQFTEGRSAREWLEHMYDKWSAELDFPVPSFAEFWRTGRLELPTRTGLTWLADFRADPAAHPLGTPSGRIEIFSDTVDAFALPDCAGHPTWYEPSEWLGGPRAARYPLHLIANQPRTRLHSQLDHGGASMASKIRGREPIRIHPDDAAARELTDGDIVRVFNDRGACLAGVVIDDGLRPKVVQLSTGAWFDPADPRDPDSMCVHGNPNALSNDSGTSSLAHGSTGQHVLVQIERFTGELPPVRAHEPPRLA
>NC_020559.1|WP_044519831.1|1611276_1612695_-|PE-family-protein
MSNVMVVPGMLSAAAADVASIGAALSAANGAAAPTTAGVLAAGADEVSAAIASLFSGYARDYQALSAQMARFHQQFVQALTASVGSYAAAEAANASPLQALEQQVLAAINAPTQTLLGRPLIGNGADGLPGQNGGAGGLLWGNGGNGGAGDAAHPNGGNGGDAGMFGNGGAGGAGYSPAAGTGAAGGAGGAGGAGGWLSGNGGAGGNGGTGASGADGGGGLPPVPASPGGNGGGGDAGGAAGMFGTGGAGGTGGDGGAGGAGDSPNSGANGARGGDGGNGAAGGAGGRLFGNGGAGGNGGTAGQGGDGGTALGAGGIGGDGGTGGAGGTGGTAGIGGGSSMIGGKGGTGGNGGVGGTGGASALTIGNGSSAGAGGAGGAGGTGGTGGYIESLDGKGQAGNGGNGGNGAAGGAGGGGTGAGGNGGAGGNGGDGGPSQGGGNPGFGGDGGTGGPGGVGVPDGIGGANGAQGKHG
>NC_020559.1|WP_003898882.1|1627817_1628744_+|protoheme-IX-farnesyltransferase
MNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH
>NC_020559.1|WP_003904629.1|1631156_1632422_+|PucR-family-transcriptional-regulator
MALRETSPRIHELIREAARIALNPTQEWLDEFDRAILAANPSIAADPALATVVKRSNRAHLIHFAAANLRNPGAPVPANLGPEPLRMARDLVRVGLDALALDIYRIGQNVAWRRWTDIAFGLTSDPDELHELLDVPFRTANEFVDTTLAGITTEMQLERDKLTRDVPAERRKIVQLLIDGAPISREHAEARLGYPLDRSHTAAVIWGDQAQGDHSHLDRVADAFGHAGGCPHPLVVVAGAATRWVWVKDAPGFDIDLIHEVLHDIPDARIAIGATAPGIEGFRRSHRDALTTARMIIRLESPHRVAFFTDVEMVALLTENAEGADDFIQRTLGNLESASPALKTTLLTFINQQCNASRAARLLFTHRNTLMNRLETAQRLLPRPLADTTIHVAVALEAQQWREKQTSDPPAKKESNGTKMR
>NC_020559.1|WP_003407462.1|1632449_1633436_-|quinone-oxidoreductase
MHAIEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPRELPFVIGSEVCGTVEAVGPGVTAADTAISVGDRVVSASANGAYAEFCTAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGDTVLVHAGAGGVGLILTQWATHLGVRVITTVSTAEKAKLSKDAGADVVLDYPEDAWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTLALFGAASGPVPPVDPQRLNAAGSVYLTRPSLFHFTRTGEEFSWRAAELFDAIGSEAITVAVGGRYPLADALRAHQDLEARKTVGSVVLLP
>NC_020559.1|WP_003900341.1|1633455_1634319_+|hypothetical-protein
MKLARPDVFHPRVVLAGWPQQPAGDGDDAGLVAALRHRGLHAGWLSWDDPEIVHADLVILRATRDYPARLDEFLAWTTRVANLLNSRPVVAWNVERRYLRDLMDRGVPTVPGEVYVPGEPVRLPRKGQVFVGPTIGTGTRRCSARFAAEFVAQLHAAGQAVLVQPGGSGDETVLVFLGGEPSHAFTKQADTWRQTEPDFEIWDVGAAAVAGAAAQVGVDPGELLYARAHITGGSRDPRLLELQLVDPSLGWQWLDPDIRNLAQRDFALCVQSALERLGLGPFSHRRP
>NC_020559.1|WP_003407466.1|1634268_1635201_-|heme-A-synthase
MPYDRAVSPSLRVQRVIAAIVILTQGGIAVTGAIVRVTASGLGCPTWPQCFPGSFTPVVVAEVPRVHQAVEFGNRMVTFAVVIAAALAVLVVTRARRRTEVLAYAWLMPVSTVVQAMIGGITVRTGLLWWTVAIHLLASMTMVWLAVLLYVKIGQPDDGVVHELVVSPLRALTALSALNLAAVLVTGTLVTAAGPHAGDRSPSRTVPRLKVEITTLVHMHSSLLVAYLALLIGLGFGLLAVGATRAILVRLAVLLALVATQAAVGTTQYFTGVPAALVAIHVAGAAAVTAATAALWASMGERAQPQPLQR
>NC_020559.1|WP_003407475.1|1635312_1636098_-|ABC-transporter-permease
MTQTNRPAFPAGTFSPDPRPNAVPLMLAAQFSLELKLLLRNGEQLLLTMFIPITLLVGLTLLPMGSFGHNRAATFVPVIMALAVISTAFTGQAIAVAFDRRYGALKRLGATPLPVWGIIAGKSLAVVAVVFLQAIILGAIGFALGWRPALTALTLGAGIIALGTAGFAALGLLLGGTLRAEIVLAVANLMWFVFAGFGALTLESNVIPTAFKWVARVTPSGALTEALSQAMTVSVDWFGIVVLAVWGALAALAALRWFRFT
>NC_020559.1|WP_003407477.1|1636094_1637036_-|ABC-transporter-ATP-binding-protein
MNRAPDTPEVVLRLRGVCKRYGSITAVSNLDLDVHDAEVMALLGPNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPITDNARLRARIGVMLQGGGGYPAARAGEMLDLVASYAANPLDPHWLLDTLGLTEAARTTYRRLSGGQQQRLALACALVGRPQLVFLDEPTAGMDAHARVLVWELIDALRRDGVTVVLTTHHLKEAEELADRLVIIDHGVTVAAGTPAELMRSGAKDQLRFTAPPRLDLSLLASALPEGYQATELTPGEYLVEGPVDPQVLATVTAWCAQIDVLATDMRVEQRSLEDVFLDLTGRKLRQ
>NC_020559.1|WP_003407479.1|1637191_1638967_-|polyprenol-phosphomannose-dependent-alpha-1,6-mannosyltransferase-MptB
MAARHHTLSWSIASLHGDEQAVGAPLTTTELTALARTRLFGATGTVLMAIGALGAGARPVVQDPTFGVRLLNLPSRIQTVSLTMTTTGAVMMALAWLMLGRFTLGRRRMSRGELDRTLLLWMLPLLIAPPMYSKDVYSYLAQSEIGRDGLDPYRVGPASGLGLGHVFTLSVPSLWRETPAPYGPLFLWIGRGISSLTGENIVAAVLCHRLVVLIGVTLIVWATPRLAQRCGVAEVSALWLGAANPLLIMHLVAGIHNEALMLGLMLTGVEFALRGLDMANTPRPSPETWRLGPATIRASRRPELGASPRAGASRAVKPRPEWGPLAMLLAGSILITLSSQVKLPSLLAMGFVTTVLAYRWGGNLRALLLAAAVMASLTLAIMAILGWASGLGFGWINTLGTANVVRSWMSPPTLLALGTGHVGILLGLGDHTTAVLSLTRAIGVLIITVMVCWLLLAVLRGRLHPIGGLGVALAVTVLLFPVVQPWYLLWAIIPLAAWATRPGFRVAAILATLIVGIFGPTANGDRFALFQIVDATAASAIIVILLIALTYTRLPWRPLAAEQVVTAAESASKTPATRRPTAAPDAYADST
>NC_020559.1|WP_003902080.1|1639014_1639821_+|suf-operon-transcriptional-regulator-SufR
MTSTTLPHRASLVDRSTEFCHTDVVKIPAVSTTVPAAVSDGHTRRAIVRLLLESGSITAGEIGDRLGLSAAGVRRHLDALIEAGDAEASAAAPWQQVGRGRPAKRYRLTAAGRAKLDHSYDDLASAAMRQLREIGGEEAVRTFARRRIDAILADVAPADGPDDAALEAAAERIATALSKAGYVATTTRVGGPIHGVQICQHHCPVSHVAEEFPELCETEQQAMAEVLGTHVQRLATIVNGDCACTTHVPLSPAPSPRPPATSTEGASR
>NC_020559.1|WP_003900342.1|1639817_1642358_+|intein-containing-Fe-S-cluster-assembly-protein-SufB
MTLTPEASKSVAQPPTQAPLTQEEAIASLGRYGYGWADSDVAGANAQRGLSEAVVRDISAKKNEPDWMLQSRLKALRIFDRKPIPKWGSNLDGIDFDNIKYFVRSTEKQAASWDDLPEDIRNTYDRLGIPEAEKQRLVAGVAAQYESEVVYHQIREDLEAQGVIFLDTDTGLREHPDIFKEYFGTVIPAGDNKFSALNTAVWSGGSFIYVPPGVHVDIPLQAYFRINTENMGQFERTLIIADEGSYVHYVEGCLPAGELITTADGDLRPIESIRVGDFVTGHDGRPHRVTAVQVRDLDGELFTFTPMSPANAFSVTAEHPLLAIPRDEVRVMRKERNGWKAEVNSTKLRSAEPRWIAAKDVAEGDFLIYPKPKPIPHRTVLPLEFARLAGYYLAEGHACLTNGCESLIFSFHSDEFEYVEDVRQACKSLYEKSGSVLIEEHKHSARVTVYTKAGYAAMRDNVGIGSSNKKLSDLLMRQDETFLRELVDAYVNGDGNVTRRNGAVWKRVHTTSRLWAFQLQSILARLGHYATVELRRPGGPGVIIGRNVVRKDIYQVQWTEGGRGPKQARDCGDYFAVPIKKRAVREAHEPVYNLDVENPDSYLAYGFAVHNCTAPIYKSDSLHSAVVEIIVKPHARVRYTTIQNWSNNVYNLVTKRARAEAGATMEWIDGNIGSKVTMKYPAVWMTGEHAKGEVLSVAFAGEDQHQDTGAKMLHLAPNTSSNIVSKSVARGGGRTSYRGLVQVNKGAHGSRSSVKCDALLVDTVSRSDTYPYVDIREDDVTMGHEATVSKVSENQLFYLMSRGLTEDEAMAMVVRGFVEPIAKELPMEYALELNRLIELQMEGAVG

Crispr_ID: NC_020559_10

• CRISPR_ID: NC_020559_10
• CRISPR_location: 2052494-2053060
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 10 spacers

Consensus repeat of NC_020559_10

Consensus_repeat	Method
CCGGCGCCGCCGGCCCCGCCGTTGCCGA	CRISPRCasFinder

spacers of NC_020559_10

>10.1|2052522|23|NC_020559|CRISPRCasFinder
CGAGCCCACCGGCGCCCCCGGCA
>10.2|2052573|29|NC_020559|CRISPRCasFinder
CGGCGCCGCCGGCACCAAACAGCAGGCCC
>10.3|2052630|20|NC_020559|CRISPRCasFinder
CCACCCCGGTAGCGCCACCG
>10.4|2052678|20|NC_020559|CRISPRCasFinder
CGGCGCCTACCAGCAGGCCG
>10.5|2052726|20|NC_020559|CRISPRCasFinder
CCACGCCGAAGAACAACCCG
>10.6|2052774|17|NC_020559|CRISPRCasFinder
CGTGGGCCGCGAGTCCG
>10.7|2052819|19|NC_020559|CRISPRCasFinder
ACAGCAGCCCGCCATTCCG
>10.8|2052866|23|NC_020559|CRISPRCasFinder
CCACCCCACCACCGGCGCGTCCG
>10.9|2052917|20|NC_020559|CRISPRCasFinder
AGAGCAGCCCGCCGGCCCCG
>10.10|2052965|68|NC_020559|CRISPRCasFinder
ACGCTACGTTCCCCCCGGCGCCGCCGGCCCCGCCGTTGCCGAACAGGCCAGCGGCTCCGCCGTTGCCC

CRISPR arrays and Neighbor proteins around NC_020559_10

CRISPR arrays

The CRISPR arrays of NC_020559_10

>merge|NC_020559|10|2052494-2053060|CRISPRCasFinder
CCGTCGCCGATCAGCCCGGCTTTGCCGCCGAGCCCACCGGCGCCCCCGGCACCGCCGAAGCCGAATCCGCCGGCGCCGCCGGCGCCGCCGGCACCAAACAGCAGGCCCGCAGTGCCGCCGTTTCCGCCGGCGCCGCCCACCCCGGTAGCGCCACCGCCGAGTGCGCCGGCGCCGCCGGCCCCGCCGGCGCCTACCAGCAGGCCGGCGGTGCCGCCGGCCCCGCCGGCACCGCCCACGCCGAAGAACAACCCGCCGTCTCCGCCGGCCCCGCCGTCACCGGCGTGGGCCGCGAGTCCGCCGACGCCGCCGGCCCCGCCGGCGCCGAACAGCAGCCCGCCATTCCGCCGGCCCCGCCGGCCCCACCAATACCGCCCACCCCACCACCGGCGCGTCCGCCGGCGCCGCCGGCCCCGCCGGGCGCGTAGAGCAGCCCGCCGGCCCCGCCGGCCCCGCCGAACCCTGCGGTGCCGGACGCTACGTTCCCCCCGGCGCCGCCGGCCCCGCCGTTGCCGAACAGGCCAGCGGCTCCGCCGTTGCCCCCGGGCATGCCGGCCGCGCCGGAGCCGC

>NC_020559|10|6|2052494-2053060|CRISPRCasFinder
CCGTCGCCGATCAGCCCGGCTTTGCCGC	CGAGCCCACCGGCGCCCCCGGCA
CCGCCGAAGCCGAATCCGCCGGCGCCGC	CGGCGCCGCCGGCACCAAACAGCAGGCCC
GCAGTGCCGCCGTTTCCGCCGGCGCCGC	CCACCCCGGTAGCGCCACCG
CCGAGTGCGCCGGCGCCGCCGGCCCCGC	CGGCGCCTACCAGCAGGCCG
GCGGTGCCGCCGGCCCCGCCGGCACCGC	CCACGCCGAAGAACAACCCG
CCGTCTCCGCCGGCCCCGCCGTCACCGG	CGTGGGCCGCGAGTCCG
CCGACGCCGCCGGCCCCGCCGGCGCCGA	ACAGCAGCCCGCCATTCCG
CCGGCCCCGCCGGCCCCACCAATACCGC	CCACCCCACCACCGGCGCGTCCG
CCGGCGCCGCCGGCCCCGCCGGGCGCGT	AGAGCAGCCCGCCGGCCCCG
CCGGCCCCGCCGAACCCTGCGGTGCCGG	ACGCTACGTTCCCCCCGGCGCCGCCGGCCCCGCCGTTGCCGAACAGGCCAGCGGCTCCGCCGTTGCCC
CCGGGCATGCCGGCCGCGCCGGAGCCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_003409218.1|2055617_2057261_+|acetolactate-synthase	unknown	unknown	gnl|CDD|235629
NC_020559.1|WP_003899038.1|2061854_2062733_+|DUF881-domain-containing-protein	unknown	unknown	gnl|CDD|226396
NC_020559.1|WP_003900416.1|2053627_2055547_-|vitamin-B12-ABC-transporter-ATP-binding-protein-BacA	unknown	unknown	gnl|CDD|226646
NC_020559.1|WP_003899040.1|2062770_2063175_+|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl|CDD|234918
NC_020559.1|WP_003900417.1|2057275_2059702_+|accessory-Sec-system-translocase-SecA2	unknown	unknown	gnl|CDD|237060
NC_020559.1|WP_003899030.1|2042485_2043892_+|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_020559.1|WP_003409207.1|2050720_2052184_+|FAD-binding-protein	unknown	unknown	gnl|CDD|180854
NC_020559.1|WP_003409188.1|2044136_2044493_+|DUF732-domain-containing-protein	unknown	unknown	gnl|CDD|368380
NC_020559.1|WP_003409227.1|2059898_2060528_+|CDP-alcohol-phosphatidyltransferase-family-protein	unknown	unknown	gnl|CDD|223632
NC_020559.1|WP_003409204.1|2048730_2049396_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003901262.1|2060520_2061444_+|DUF881-domain-containing-protein	unknown	unknown	gnl|CDD|226396
NC_020559.1|WP_003409205.1|2049458_2050163_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379115
NC_020559.1|WP_003409199.1|2046883_2047315_-|DUF4189-domain-containing-protein	unknown	unknown	gnl|CDD|372741
NC_020559.1|WP_003899037.1|2061472_2061838_+|small-basic-family-protein	unknown	unknown	gnl|CDD|226374
NC_020559.1|WP_003409179.1|2039589_2040801_+|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_020559.1|WP_003899041.1|2063414_2063903_+|glycogen-accumulation-regulator-GarA	unknown	unknown	gnl|CDD|224630
NC_020559.1|WP_003906680.1|2041124_2042354_+|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_020559.1|WP_003901259.1|2047723_2048626_+|sterol-desaturase-family-protein	unknown	unknown	gnl|CDD|225546
NC_020559.1|WP_003409239.1|2063899_2064643_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133378
NC_020559.1|WP_003900414.1|2044646_2045351_+|MgtC/SapB-family-protein	unknown	unknown	gnl|CDD|224204

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_003409218.1|2055617_2057261_+|acetolactate-synthase	gnl|CDD|235629	PRK05858, PRK05858, acetolactate synthase.	0
NC_020559.1|WP_003899038.1|2061854_2062733_+|DUF881-domain-containing-protein	gnl|CDD|226396	COG3879, COG3879, Uncharacterized protein conserved in bacteria [Function unknown].	5.64423e-80
NC_020559.1|WP_003900416.1|2053627_2055547_-|vitamin-B12-ABC-transporter-ATP-binding-protein-BacA	gnl|CDD|226646	COG4178, COG4178, ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only].	0
NC_020559.1|WP_003899040.1|2062770_2063175_+|glycine-cleavage-system-protein-GcvH	gnl|CDD|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	1.57956e-64
NC_020559.1|WP_003900417.1|2057275_2059702_+|accessory-Sec-system-translocase-SecA2	gnl|CDD|237060	PRK12326, PRK12326, preprotein translocase subunit SecA; Reviewed.	0
NC_020559.1|WP_003899030.1|2042485_2043892_+|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	3.25979e-58
NC_020559.1|WP_003409207.1|2050720_2052184_+|FAD-binding-protein	gnl|CDD|180854	PRK07121, PRK07121, FAD-binding protein.	0
NC_020559.1|WP_003409188.1|2044136_2044493_+|DUF732-domain-containing-protein	gnl|CDD|368380	pfam05305, DUF732, Protein of unknown function (DUF732). This family consists of several uncharacterized Mycobacterium tuberculosis and leprae proteins of unknown function.	2.00134e-24
NC_020559.1|WP_003409227.1|2059898_2060528_+|CDP-alcohol-phosphatidyltransferase-family-protein	gnl|CDD|223632	COG0558, PgsA, Phosphatidylglycerophosphate synthase [Lipid metabolism].	2.43578e-28
NC_020559.1|WP_003901262.1|2060520_2061444_+|DUF881-domain-containing-protein	gnl|CDD|226396	COG3879, COG3879, Uncharacterized protein conserved in bacteria [Function unknown].	2.39339e-84
NC_020559.1|WP_003409205.1|2049458_2050163_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	2.04829e-11
NC_020559.1|WP_003409199.1|2046883_2047315_-|DUF4189-domain-containing-protein	gnl|CDD|372741	pfam13827, DUF4189, Domain of unknown function (DUF4189). This domain of unknown function contains six well-conserved cysteine residues.	4.20219e-12
NC_020559.1|WP_003899037.1|2061472_2061838_+|small-basic-family-protein	gnl|CDD|226374	COG3856, Sbp, Uncharacterized conserved protein (small basic protein) [Function unknown].	1.86148e-45
NC_020559.1|WP_003409179.1|2039589_2040801_+|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	2.51889e-57
NC_020559.1|WP_003899041.1|2063414_2063903_+|glycogen-accumulation-regulator-GarA	gnl|CDD|224630	COG1716, COG1716, FOG: FHA domain [Signal transduction mechanisms].	3.81746e-35
NC_020559.1|WP_003906680.1|2041124_2042354_+|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	9.20919e-57
NC_020559.1|WP_003901259.1|2047723_2048626_+|sterol-desaturase-family-protein	gnl|CDD|225546	COG3000, ERG3, Sterol desaturase [Lipid metabolism].	1.47599e-56
NC_020559.1|WP_003409239.1|2063899_2064643_+|MerR-family-transcriptional-regulator	gnl|CDD|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	3.6505e-17
NC_020559.1|WP_003900414.1|2044646_2045351_+|MgtC/SapB-family-protein	gnl|CDD|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	1.22516e-68

Protein sequences

>NC_020559.1|WP_003409207.1|2050720_2052184_+|FAD-binding-protein
MSTDIPATVSAETVTSWSDDVDVTVIGFGIAGGCAAVSAAAAGARVLVLERAAAAGGTTALAGGHFYLGGGTTVQLATGHPDSPEEMYKYLVAVSREPDHDKIRAYCDGSVEHFNWLEGLGFQFERSYFPGKAVIQPNTEGLMFTGNEKVWPFLELAVPAPRGHKVPVPGDTGGAAMVIDLLLKRAASLGIQIRYETGATELIVDGTGKVTGVMWKRFSETGAIKAKSVIIAAGGFVMNPDMVAKYTPKLAEKPFVLGNTYDDGLGIRLGVSAGGATQHMDQMFITAPPYPPSILLTGIIVNKLGQRFVAEDSYHSRTAGFIMEQPDSAAYLIVDEAHLEHPKMPLVPLIDGWETVVEMEAALGIPPGNLAATLDRYNAYAARGADPDFHKQPEFLAAQDNGPWGAFDMSLGKAMYAGFTLGGLATSVDGQVLRDDGAVVAGLYAVGACASNIAQDGKGYASGTQLGEGSFFGRRAGAHAAARAQGM
>NC_020559.1|WP_003409205.1|2049458_2050163_+|TetR/AcrR-family-transcriptional-regulator
MCQTCRVGKRRDAREQIEAKIVELGRRQLLDHGAAGLSLRAIARNLGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVDRARDDTVADSWSDDVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRVVGAFFDAIAAGIATGDIRLTDDVAPQPMSSDFEKIRQEFGFPGDDRVVTKCFLLWAGVVGAISLEVFGQYGADMLTDPGVVFDAQTRLLVAVLAEH
>NC_020559.1|WP_003409204.1|2048730_2049396_+|hypothetical-protein
MVRLVPRAFAATVALLAAGFSPATASADPVLVFPGMEIRQDNHVCTLGYVDPALKIAFTAGHCRGGGAVTSRDYKVIGHLRAFRDNTPSGSTVATHELIADYEAIVLADDVTASNILPSGRALESRPGVVLHPGQAVCHFGVSTGETCGTVESVNNGWFTMSHGVLSEKGDSGGPVYLAPDGGPAQIVGIFNSVWGGFPAAVSWRSTSEQVHADLGVTPLA
>NC_020559.1|WP_003901259.1|2047723_2048626_+|sterol-desaturase-family-protein
MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSIATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTERIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLTKRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEPRTIDKSNAAASLVTSR
>NC_020559.1|WP_003409199.1|2046883_2047315_-|DUF4189-domain-containing-protein
MITNLRRRTAMAAAGLGAALGLGILLVPTVDAHLANGSMSEVMMSEIAGLPIPPIIHYGAIAYAPSGASGKAWHQRTPARAEQVALEKCGDKTCKVVSRFTRCGAVAYNGSKYQGGTGLTRRAAEDDAVNRLEGGRIVNWACN
>NC_020559.1|WP_003900414.1|2044646_2045351_+|MgtC/SapB-family-protein
MQTLTVADFALRLAVGVGCGAIIGLERQWRARMAGLRTNALVATGATLFVLYAVATEDSSPTRVASYVVSGIGFLGGGVILREGFNVRGLNTAATLWCSAAVGVLAASGHLVFTLIGTGTIVAVHLLGRPLGRLVDRDNAVEDEGLQPYQVRVICRPKAETYVRAHIVQRTSSNDITLRGIHTGPAGDDNITLTAHLLMVGHTPAKLERLVAELSLQPGVYAVHWYAGEHAQAE
>NC_020559.1|WP_003409188.1|2044136_2044493_+|DUF732-domain-containing-protein
MQLQRTMGQCRPMRMLVALLLSAATMIGLAAPGKADPTGDDAAFLAALDQAGITYADPGHAITAAKAMCGLCANGVTGLQLVADLRDYNPGLTMDSAAKFAAIASGAYCPEHLEHHPS
>NC_020559.1|WP_003899030.1|2042485_2043892_+|PPE-family-protein
MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGPSSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISLVATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLAGQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAIFGPTGATTYQNLFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPPAPEIPKSSLGAGLGLRSGLSAGLAHAASAGLGQANLVGDLSVPPSWASATPAVRLVANTLPATSLAAAPATQIPANLLGQMALGSMTGGALGAAAPAIYTGSGARARANGGTPSAEPVKLEAVIAQLQKQPDAVRHWNVDKADLDGLLDRLSKQPGIHAVHVSNGDKPKVALPDTQLGSH
>NC_020559.1|WP_003906680.1|2041124_2042354_+|PPE-family-protein
MDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGALFGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD
>NC_020559.1|WP_003409179.1|2039589_2040801_+|PPE-family-protein
MTAALDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGPASASMTAAAAPYVAWMSVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQLMALIATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGASAAATQLTPFTEPVQTTNASGLAAQSAAIAHATGASAGAQQTTLSQLIAAIPSVLQGLSSSTAATSASGPSGLLGILGSGSSWLDKLWALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVAAADAAGDVLGEATSGGLGGALVAPLGSAGGLGGTVAAGLGNAATVGTLSVPPSWTAAAPLASPLGSALGGTPMVAPPPAVAAGMPGMPFGTMGGQGFGRAVPQYGFRPNFVARPPAAG
>NC_020559.1|WP_003900416.1|2053627_2055547_-|vitamin-B12-ABC-transporter-ATP-binding-protein-BacA
MGPKLFKPSIDWSRAFPDSVYWVGKAWTISAICVLAILVLLRYLTPWGRQFWRITRAYFVGPNSVRVWLMLGVLLLSVVLAVRLNVLFSYQGNDMYTALQKAFEGIASGDGTVKRSGVRGFWMSIGVFSVMAVLHVTRVMADIYLTQRFIIAWRVWLTHHLTQDWLDGRAYYRDLFIDETIDNPDQRIQQDVDIFTAGAGGTPNAPSNGTASTLLFGAVQSIISVISFTAILWNLSGTLNIFGVSIPRAMFWTVLVYVFVATVISFIIGRPLIWLSFRNEKLNAAFRYALVRLRDAAEAVGFYRGERVEGTQLQRRFTPVIDNYRRYVRRSIAFNGWNLSVSQTIVPLPWVIQAPRLFAGQIDFGDVGQTATSFGNIHDSLSFFRNNYDAFASFRAAIIRLHGLVDANEKGRALPAVLTRPSDDESVELNDIEVRTPAGDRLIDPLDVRLDRGGSLVITGRSGAGKTTLLRSLAELWPYASGTLHRPGGENETMFLSQLPYVPLGTLRDVVCYPNSAAAIPDATLRDTLTKVALAPLCDRLDEERDWAKVLSPGEQQRVAFARILLTKPKAVFLDESTSALDTGLEFALYQLLRSELPDCIVISVSHRPALERLHENQLELLGGGQWRLAPVEAAPAEV
>NC_020559.1|WP_003409218.1|2055617_2057261_+|acetolactate-synthase
MSTDTAPAQTMHAGRLIARRLKASGIDTVFTLSGGHLFSIYDGCREEGIRLIDTRHEQTAAFAAEGWSKVTRVPGVAALTAGPGITNGMSAMAAAQQNQSPLVVLGGRAPALRWGMGSLQEIDHVPFVAPVARFAATAQSAENAGLLVDQALQAAVSAPSGVAFVDFPMDHAFSMSSDNGRPGALTELPAGPTPAGDALDRAAGLLSTAQRPVIMAGTNVWWGHAEAALLRLVEERHIPVLMNGMARGVVPADHRLAFSRARSKALGEADVALIVGVPMDFRLGFGGVFGSTTQLIVADRVEPAREHPRPVAAGLYGDLTATLSALAGSGGTDHQGWIEELATAETMARDLEKAELVDDRIPLHPMRVYAELAALLERDALVVIDAGDFGSYAGRMIDSYLPGCWLDSGPFGCLGSGPGYALAAKLARPQRQVVLLQGDGAFGFSGMEWDTLVRHNVAVVSVIGNNGIWGLEKHPMEALYGYSVVAELRPGTRYDEVVRALGGHGELVSVPAELRPALERAFASGLPAVVNVLTDPSVAYPRRSNLA
>NC_020559.1|WP_003900417.1|2057275_2059702_+|accessory-Sec-system-translocase-SecA2
MNVHGCPRIAACRCTDTHPRGRPAFAYRWFVPKTTRAQPGRLSSRFWRLLGASTEKNRRRSLADVTASAEYDKEAADLSDEKLRKAAGLLNLDDLAESADIPQFLAIAREAAERRTGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGAIAAAGYALAGRHVHVVTINDYLARRDAEWMGPLLDAMGLTVGWITADSTPDERRTAYDRDVTYASVNEIGFDVLRDQLVTDVNDLVSPNPDVALIDEADSVLVDEALVPLVLAGTTHRETPRLEIIRLVAELVGDKDADEYFATDSDNRNVHLTEHGARKVEKALGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYIVRDDAVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITVQALINRYATVCGMTGTALAAGEQLRQFYQLGVSPIPPNKPNIREDEADRVYITTAAKNDGIVEHITEVHQRGQPVLVGTRDVAESEELHERLVRRGVPAVVLNAKNDAEEARVIAEAGKYGAVTVSTQMAGRGTDIRLGGSDEADHDRVAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDVVAANLDHNKLPMATDENGRIVSPRTGSLLDHAQRVAEGRLLDVHANTWRYNQLIAQQRAIIVERRNTLLRTVTAREELAELAPKRYEELSDKVSEERLETICRQIMLYHLDRGWADHLAYLADIRESIHLRALGRQNPLDEFHRMAVDAFASLAADAIEAAQQTFETANVLDHEPGLDLSKLARPTSTWTYMVNDNPLSDDTLSALSLPGVFR
>NC_020559.1|WP_003409227.1|2059898_2060528_+|CDP-alcohol-phosphatidyltransferase-family-protein
MEPVLTQNRVLTVPNMLSVIRLALIPAFVYVVLSAHANGWGVAILVFSGVSDWADGKIARLLNQSSRLGALLDPAVDRLYMVTVPIVFGLSGIVPWWFVLTLLTRDALLAGTLPLLWSRGLSALPVTYVGKAATFGFMVGFPTILLGQCDPLWSHVLLACGWAFLIWGMYAYLWAFVLYAVQMTMVVRQMPKLKGRAHRPAAQNAGERG
>NC_020559.1|WP_003901262.1|2060520_2061444_+|DUF881-domain-containing-protein
MAESDRLLGGYDPNAGYSAHAGAQPQRIPVPSLLRALLSEHLDAGYAAVAAERERAAAPRCWQARAVSWMWQALAATLVAAVFAAAVAQARSVAPGVRAAQQLLVASVRSTQAAATTLAQRRSTLSAKVDDVRRIVLADDAEGQRLLARLDVLSLAAASAPVVGPGLTVTVTDPGASPNLSDVSKQRVSGSQQIILDRDLQLVVNSLWESGAEAISIDGVRIGPNVTIRQAGGAILVDNNPTSSPYTILAVGPPHAMQDVFDRSAGLYRLRLLETSYGVGVSVNVGDGLALPAGATRDVKFAKQIGP
>NC_020559.1|WP_003899037.1|2061472_2061838_+|small-basic-family-protein
MGSDTAWSPARMIGIAALAVGIVLGLVFHPGVPEVIQPYLPIAVVAALDAVFGGLRAYLERIFDPKVFVVSFVFNVLVAALIVYVGDQLGVGTQLSTAIIVVLGIRIFGNTAALRRRLFGA
>NC_020559.1|WP_003899038.1|2061854_2062733_+|DUF881-domain-containing-protein
MSENRPEPVAAETSAATTARHSQADAGAHDAVRRGRHELPADHPRSKVGPLRRTRLTEILRGGRSRLVFGTLAILLCLVLGVAIVTQVRQTDSGDSLETARPADLLVLLDSLRQREATLNAEVIDLQNTLNALQASGNTDQAALESAQARLAALSILVGAVGATGPGVMITIDDPGPGVAPEVMIDVINELRAAGAEAIQINDAHRSVRVGVDTWVVGVPGSLTVDTKVLSPPYSILAIGDPPTLAAAMNIPGGAQDGVKRVGGRMVVQQADRVDVTALRQPKQHQYAQPVK
>NC_020559.1|WP_003899040.1|2062770_2063175_+|glycine-cleavage-system-protein-GcvH
MSDIPSDLHYTAEHEWIRRSGDDTVRVGITDYAQSALGDVVFVQLPVIGTAVTAGETFGEVESTKSVSDLYAPISGKVSEVNSDLDGTPQLVNSDPYGAGWLLDIQVDSSDVAALESALTTLLDAEAYRGTLTE
>NC_020559.1|WP_003899041.1|2063414_2063903_+|glycogen-accumulation-regulator-GarA
MTDMNPDIEKDQTSDEVTVETTSVFRADFLSELDAPAQAGTESAVSGVEGLPPGSALLVVKRGPNAGSRFLLDQAITSAGRHPDSDIFLDDVTVSRRHAEFRLENNEFNVVDVGSLNGTYVNREPVDSAVLANGDEVQIGKFRLVFLTGPKQGEDDGSTGGP
>NC_020559.1|WP_003409239.1|2063899_2064643_+|MerR-family-transcriptional-regulator
MSAPDSPALAGMSIGAVLDLLRPDFPDVTISKIRFLEAEGLVTPRRASSGYRRFTAYDCARLRFILTAQRDHYLPLKVIRAQLDAQPDGELPPFGSPYVLPRLVPVAGDSAGGVGSDTASVSLTGIRLSREDLLERSEVADELLTALLKAGVITTGPGGFFDEHAVVILQCARALAEYGVEPRHLRAFRSAADRQSDLIAQIAGPLVKAGKAGARDRADDLAREVAALAITLHTSLIKSAVRDVLHR

Crispr_ID: NC_020559_11

• CRISPR_ID: NC_020559_11
• CRISPR_location: 2079108-2079362
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of NC_020559_11

Consensus_repeat	Method
GCCNCCGTCGCCGCCNNTGCC	CRT

spacers of NC_020559_11

>11.1|2079129|39|NC_020559|CRT
ACCGCCGGGGGCGAAGACGCCGGTACCGGCGGACCCGGC
>11.2|2079189|18|NC_020559|CRT
GATCAGCCCGACGGCGTT
>11.3|2079228|30|NC_020559|CRT
TCGGAGAAAGCCGTCGGTTTGCACGCTGTT
>11.4|2079279|18|NC_020559|CRT
GATCAGCGTCCCGCCGGT
>11.5|2079318|24|NC_020559|CRT
ATCGAAGAAGCTGAACCCGCCGTT

CRISPR arrays and Neighbor proteins around NC_020559_11

CRISPR arrays

The CRISPR arrays of NC_020559_11

>merge|NC_020559|11|2079108-2079362|CRT
GCCTCCGTTCCCGCCACTGCCACCGCCGGGGGCGAAGACGCCGGTACCGGCGGACCCGGCGCCTCCGGCGCCACCGTTGCCGATCAGCCCGACGGCGTTGCCGCCGTCGCCGCCGTGGCCTCGGAGAAAGCCGTCGGTTTGCACGCTGTTGCCGCCGTCGCCGCCGTTGCCGATCAGCGTCCCGCCGGTGCCGCCGTCGCCGCCGTTGCCATCGAAGAAGCTGAACCCGCCGTTACCGCCGTCGCCGAACATCCC

>NC_020559|11|1|2079108-2079362|CRT
GCCTCCGTTCCCGCCACTGCC	ACCGCCGGGGGCGAAGACGCCGGTACCGGCGGACCCGGC
GCCTCCGGCGCCACCGTTGCC	GATCAGCCCGACGGCGTT
GCCGCCGTCGCCGCCGTGGCC	TCGGAGAAAGCCGTCGGTTTGCACGCTGTT
GCCGCCGTCGCCGCCGTTGCC	GATCAGCGTCCCGCCGGT
GCCGCCGTCGCCGCCGTTGCC	ATCGAAGAAGCTGAACCCGCCGTT
ACCGCCGTCGCCGAACATCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_003409255.1|2070648_2071515_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NC_020559.1|WP_003409298.1|2086030_2086981_-|M56-family-metallopeptidase	unknown	unknown	gnl|CDD|320685
NC_020559.1|WP_003409271.1|2075574_2077800_-|malate-synthase-G	unknown	unknown	gnl|CDD|235097
NC_020559.1|WP_003409301.1|2086995_2087412_-|transcriptional-repressor-BlaI	unknown	unknown	gnl|CDD|226207
NC_020559.1|WP_003902189.1|2083077_2084517_-|GuaB1-family-IMP-dehydrogenase-related-protein	unknown	unknown	gnl|CDD|181127
NC_020559.1|WP_003899046.1|2081536_2082904_-|HlyC/CorC-family-transporter	unknown	unknown	gnl|CDD|224173
NC_020559.1|WP_003409308.1|2088459_2088774_+|urease-subunit-beta	unknown	unknown	gnl|CDD|106171
NC_020559.1|WP_003409254.1|2069747_2070608_-|haloalkane-dehalogenase	unknown	unknown	gnl|CDD|179554
NC_020559.1|WP_003409244.1|2065659_2066337_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133380
NC_020559.1|WP_003901265.1|2073421_2075455_-|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|238733
NC_020559.1|WP_003409284.1|2084549_2086001_-|NADP-dependent-phosphogluconate-dehydrogenase	unknown	unknown	gnl|CDD|236453
NC_020559.1|WP_003409305.1|2088160_2088463_+|urease-subunit-gamma	unknown	unknown	gnl|CDD|376347
NC_020559.1|WP_003900419.1|2080499_2081537_-|HlyC/CorC-family-transporter	unknown	unknown	gnl|CDD|224173
NC_020559.1|WP_003409276.1|2078467_2078731_-|antitoxin	unknown	unknown	unknown
NC_020559.1|WP_003409258.1|2071519_2073406_-|CocE/NonD-family-hydrolase	unknown	unknown	gnl|CDD|273375
NC_020559.1|WP_003899049.1|2088773_2090507_+|urease-subunit-alpha	unknown	unknown	gnl|CDD|237304
NC_020559.1|WP_003409273.1|2078075_2078471_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|224761
NC_020559.1|WP_003900418.1|2066695_2069521_+|aminomethyl-transferring-glycine-dehydrogenase	unknown	unknown	gnl|CDD|235432
NC_020559.1|WP_003899048.1|2087689_2088112_+|PaaI-family-thioesterase	unknown	unknown	gnl|CDD|224961
NC_020559.1|WP_003409242.1|2064761_2065256_+|bifunctional-nuclease-family-protein	unknown	unknown	gnl|CDD|376830

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_003409255.1|2070648_2071515_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	6.65147e-19
NC_020559.1|WP_003409298.1|2086030_2086981_-|M56-family-metallopeptidase	gnl|CDD|320685	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain ?-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	3.1451e-26
NC_020559.1|WP_003409271.1|2075574_2077800_-|malate-synthase-G	gnl|CDD|235097	PRK02999, PRK02999, malate synthase G; Provisional.	0
NC_020559.1|WP_003409301.1|2086995_2087412_-|transcriptional-repressor-BlaI	gnl|CDD|226207	COG3682, COG3682, Predicted transcriptional regulator [Transcription].	1.25443e-40
NC_020559.1|WP_003902189.1|2083077_2084517_-|GuaB1-family-IMP-dehydrogenase-related-protein	gnl|CDD|181127	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein.	0
NC_020559.1|WP_003899046.1|2081536_2082904_-|HlyC/CorC-family-transporter	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	8.70643e-128
NC_020559.1|WP_003409308.1|2088459_2088774_+|urease-subunit-beta	gnl|CDD|106171	PRK13202, ureB, urease subunit beta; Reviewed.	3.42156e-64
NC_020559.1|WP_003409254.1|2069747_2070608_-|haloalkane-dehalogenase	gnl|CDD|179554	PRK03204, PRK03204, haloalkane dehalogenase; Provisional.	0
NC_020559.1|WP_003409244.1|2065659_2066337_+|MerR-family-transcriptional-regulator	gnl|CDD|133380	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators. Helix-turn-helix (HTH) transcription regulator GlnR and related proteins, N-terminal domain. The GlnR and TnrA (also known as ScgR) proteins have been shown to regulate expression of glutamine synthetase as well as several genes involved in nitrogen metabolism. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	6.61772e-22
NC_020559.1|WP_003901265.1|2073421_2075455_-|substrate-binding-domain-containing-protein	gnl|CDD|238733	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Not much is known about the function of the members of this subgroup. All members of this subgroup however have a conserved MIDAS motif. .	3.79869e-39
NC_020559.1|WP_003409284.1|2084549_2086001_-|NADP-dependent-phosphogluconate-dehydrogenase	gnl|CDD|236453	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase.	0
NC_020559.1|WP_003409305.1|2088160_2088463_+|urease-subunit-gamma	gnl|CDD|376347	pfam00547, Urease_gamma, Urease, gamma subunit. Urease is a nickel-binding enzyme that catalyzes the hydrolysis of urea to carbon dioxide and ammonia.	1.78898e-65
NC_020559.1|WP_003900419.1|2080499_2081537_-|HlyC/CorC-family-transporter	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	1.8319e-96
NC_020559.1|WP_003409258.1|2071519_2073406_-|CocE/NonD-family-hydrolase	gnl|CDD|273375	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c., putative hydrolase, CocE/NonD family. This model represents a protein subfamily that includes the cocaine esterase CocE, several glutaryl-7-ACA acylases, and the putative diester hydrolase NonD of Streptomyces griseus (all hydrolases). This family shows extensive, low-level similarity to a family of xaa-pro dipeptidyl-peptidases, and local similarity by PSI-BLAST to many other hydrolases. [Unknown function, Enzymes of unknown specificity].	0
NC_020559.1|WP_003899049.1|2088773_2090507_+|urease-subunit-alpha	gnl|CDD|237304	PRK13206, ureC, urease subunit alpha; Reviewed.	0
NC_020559.1|WP_003409273.1|2078075_2078471_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|224761	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	1.16634e-21
NC_020559.1|WP_003900418.1|2066695_2069521_+|aminomethyl-transferring-glycine-dehydrogenase	gnl|CDD|235432	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase.	0
NC_020559.1|WP_003899048.1|2087689_2088112_+|PaaI-family-thioesterase	gnl|CDD|224961	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis, transport, and catabolism].	8.89234e-31
NC_020559.1|WP_003409242.1|2064761_2065256_+|bifunctional-nuclease-family-protein	gnl|CDD|376830	pfam02577, DNase-RNase, Bifunctional nuclease. This family is a bifunctional nuclease, with both DNase and RNase activity. It forms a wedge-shaped dimer, with each monomer being triangular in shape. A large groove at the thick end of the wedge contains a possible active site.	1.28808e-61

Protein sequences

>NC_020559.1|WP_003409276.1|2078467_2078731_-|antitoxin
MSKRLQVLLDPDEWEELREIARRHRTTVSEWVRRTLREAREREPRGDLDMKLRSVRAAARHEFPTADVEQMLEEIERGRGAEREGSR
>NC_020559.1|WP_003409273.1|2078075_2078471_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MILVDSNIPMYLVGASHPHKLDAQRLLESALSGGERLVTDAEVLQEICHRYVAIKRREAIQPAFDAIIGVVDEVLPIERTDVEHARDALLRYQTLSARDALHIAVMAHHDITRLMSFDRGFDSYPGIKRLA
>NC_020559.1|WP_003409271.1|2075574_2077800_-|malate-synthase-G
MTDRVSVGNLRIARVLYDFVNNEALPGTDIDPDSFWAGVDKVVADLTPQNQALLNARDELQAQIDKWHRRRVIEPIDMDAYRQFLTEIGYLLPEPDDFTITTSGVDAEITTTAGPQLVVPVLNARFALNAANARWGSLYDALYGTDVIPETDGAEKGPTYNKVRGDKVIAYARKFLDDSVPLSSGSFGDATGFTVQDGQLVVALPDKSTGLANPGQFAGYTGAAESPTSVLLINHGLHIEILIDPESQVGTTDRAGVKDVILESAITTIMDFEDSVAAVDAADKVLGYRNWLGLNKGDLAAAVDKDGTAFLRVLNRDRNYTAPGGGQFTLPGRSLMFVRNVGHLMTNDAIVDTDGSEVFEGIMDALFTGLIAIHGLKASDVNGPLINSRTGSIYIVKPKMHGPAEVAFTCELFSRVEDVLGLPQNTMKIGIMDEERRTTVNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPMVRKGTMKSQPWILAYEDHNVDAGLAAGFSGRAQVGKGMWTMTELMADMVETKIAQPRAGASTAWVPSPTAATLHALHYHQVDVAAVQQGLAGKRRATIEQLLTIPLAKELAWAPDEIREEVDNNCQSILGYVVRWVDQGVGCSKVPDIHDVALMEDRATLRISSQLLANWLRHGVITSADVRASLERMAPLVDRQNAGDVAYRPMAPNFDDSIAFLAAQELILSGAQQPNGYTEPILHRRRREFKARAAEKPAPSDRAGDDAAR
>NC_020559.1|WP_003901265.1|2073421_2075455_-|substrate-binding-domain-containing-protein
MGRHSKPDPEDSVDDLSDGHAAEQQHWEDISGSYDYPGVDQPDDGPLSSEGHYSAVGGYSASGSEDYPDIPPRPDWEPTGAEPIAAAPPPLFRFGHRGPGDWQAGHRSADGRRGVSIGVIVALVAVVVMVAGVILWRFFGDALSNRSHTAAARCVGGKDTVAVIADPSIADQVKESADSYNASAGPVGDRCVAVAVTSAGSDAVINGFIGKWPTELGGQPGLWIPSSSISAARLTGAAGSQAISDSRSLVISPVLLAVRPELQQALANQNWAALPGLQTNPNSLSGLDLPAWGSLRLAMPSSGNGDAAYLAGEAVAAASAPAGAPATAGIGAVRTLMGARPKLADDSLTAAMDTLLKPGDVATAPVHAVVTTEQQLFQRGQSLSDAENTLGSWLPPGPAAVADYPTVLLSGAWLSQEQTSAASAFARYLHKPEQLAKLARAGFRVSDVKPPSSPVTSFPALPSTLSVGDDSMRATLADTMVTASAGVAATIMLDQSMPNDEGGNSRLSNVVAALENRIKAMPPSSVVGLWTFDGREGRTEVPAGPLADPVNGQPRPAALTAALGKQYSSGGGAVSFTTLRLIYQEMLANYRVGQANSVLVITAGPHTDQTLDGPGLQDFIRKSADPAKPIAVNIIDFGADPDRATWEAVAQLSGGSYQNLETSASPDLATAVNIFLS
>NC_020559.1|WP_003409258.1|2071519_2073406_-|CocE/NonD-family-hydrolase
MTRRGGSDAAWYSAPDQRSAYPRYRGMRYSSCYVTMRDGVRIAIDLYLPAGLTSAARLPAILHQTRYYRSLQLRWPLRMLLGGKPLQHIAADKRRRRRFVASGYAWVDVDVRGSGASFGARVCEWSSDEIRDGAEIVDWIVRQPWCNGTVAALGNSYDGTSAELLLVNQHPAVRVIAPCFSLFDVYTDIAFPGGIHAAWFTDTWGRYNEALDRNALHEVVGWWAKLPVTGMQPVQEDRDRSLRDGAIAAHRGNYDVHQIAGSLTFRDDVSASDPYRGQPDARLEPIGTPIESGSINLISPHNYWRDVQASGAAIYSYSGWFDGGYAHAAIKRFLTVSTPGSHLILGPWNHTGGWRVDPLRGLSRPDFDHDGELLRFIDHHVKGADTGIGSEPPVHYFTMVENRWKSADTWPPPATTQSYYLSADRQLRPDAPDCDSGADEYVVDQTAGTGERSRWRSQVGIGGHVCYPDRKAQDAKLLTYTSAPLDHPLEVTGHVVVTLFITSTSSDGTFFVYLEDVDPRGRVAYITEGQLRAIHRRLSDGPPPYRQVVPYRTFASGDAWPLVPGEIARLTFDLLPTSYLFQPGHRIRIAIAGADASHFAILPGCAPTVRVYRSRMHASRIDLPVIQP
>NC_020559.1|WP_003409255.1|2070648_2071515_+|alpha/beta-hydrolase
MTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWVTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDPVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD
>NC_020559.1|WP_003409254.1|2069747_2070608_-|haloalkane-dehalogenase
MSIDFTPDPQLYPFESRWFDSSRGRIHYVDEGTGPPILLCHGNPTWSFLYRDIIVALRDRFRCVAPDYLGFGLSERPSGFGYQIDEHARVIGEFVDHLGLDRYLSMGQDWGGPISMAVAVERADRVRGVVLGNTWFWPADTLAMKAFSRVMSSPPVQYAILRRNFFVERLIPAGTEHRPSSAVMAHYRAVQPNAAARRGVAEMPKQILAARPLLARLAREVPATLGTKPTLLIWGMKDVAFRPKTIIPRLSATFPDHVLVELPNAKHFIQEDAPDRIAAAIIERFG
>NC_020559.1|WP_003900418.1|2066695_2069521_+|aminomethyl-transferring-glycine-dehydrogenase
MSDHSTFADRHIGLDSQAVATMLAVIGVDSLDDLAVKAVPAGILDTLTDTGAAPGLDSLPPAASEAEALAELRALADANTVAVSMIGQGYYDTHTPPVLLRNIIENPAWYTAYTPYQPEISQGRLEALLNFQTLVTDLTGLEIANASMLDEGTAAAEAMTLMHRAARGPVKRVVVDADVFTQTAAVLATRAKPLGIEIVTADLRAGLPDGEFFGVIAQLPGASGRITDWSALVQQAHDRGALVAVGADLLALTLIAPPGEIGADVAFGTTQRFGVPMGFGGPHAGYLAVHAKHARQLPGRLVGVSVDSDGTPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAAMYASYHGAGGLTAIARRVHAHAEAIAGALGDALVHDKYFDTVLARVPGRADEVLARAKANGINLWRVDADHVSVACDEATTDTHVAVVLDAFGVAAAAPAHTDIATRTSEFLTHPAFTQYRTETSMMRYLRALADKDIALDRSMIPLGSCTMKLNAAAEMESITWPEFGRQHPFAPASDTAGLRQLVADLQSWLVLITGYDAVSLQPNAGSQGEYAGLLAIHEYHASRGEPHRDICLIPSSAHGTNAASAALAGMRVVVVDCHDNGDVDLDDLRAKVGEHAERLSALMITYPSTHGVYEHDIAEICAAVHDAGGQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVAVRAHLAPFLPGHPFAPELPKGYPVSSAPYGSASILPITWAYIRMMGAEGLRAASLTAITSANYIARRLDEYYPVLYTGENGMVAHECILDLRGITKLTGITVDDVAKRLADYGFHAPTMSFPVAGTLMVEPTESESLAEVDAFCEAMIGIRAEIDKVGAGEWPVDDNPLRGAPHTAQCLLASDWDHPYTREQAAYPLGTAFRPKVWPAVRRIDGAYGDRNLVCSCPPVEAFA
>NC_020559.1|WP_003409244.1|2065659_2066337_+|MerR-family-transcriptional-regulator
MTQLVTRARSARGSTLGEQPRQDQLDFADHTGTAGDGNDGAAAASGPVQPGLFPDDSVPDELVGYRGPSACQIAGITYRQLDYWARTSLVVPSIRSAAGSGSQRLYSFKDILVLKIVKRLLDTGISLHNIRVAVDHLRQRGVQDLANITLFSDGTTVYECTSAEEVVDLLQGGQGVFGIAVSGAMRELTGVIADFHGERADGGESIAAPEDELASRRKHRDRKIG
>NC_020559.1|WP_003409242.1|2064761_2065256_+|bifunctional-nuclease-family-protein
MGEVRVVGIRVEQPQNQPVLLLREANGDRYLPIWIGQSEAAAIALEQQGVEPPRPLTHDLIRDLIAALGHSLKEVRIVDLQEGTFYADLIFDRNIKVSARPSDSVAIALRVGVPIYVEEAVLAQAGLLIPDESDEEATTAVREDEVEKFKEFLDSVSPDDFKAT
>NC_020559.1|WP_003900419.1|2080499_2081537_-|HlyC/CorC-family-transporter
MDVLSAVLLALLLIGANAFFVGAEFALISARRDRLEALAEQGKATAVTVIRAGEQLPAMLTGAQLGVTVSSILLGRVGEPAVVKLLQLSFGLSGVPPALLHTLSLAIVVALHVLLGEMVPKNIALAGPERTAMLLVPPYLVYVRLARPFIAFYNNCANAILRLVGVQPKDELDIAVSTAELSEMIAESLSEGLLDHEEHTRLTRALRIRTRLVADVAVPLVNIRAVQVSAVGSGPTIGGVEQALAQTGYSRFPVVDRGGRFIGYLHIKDVLTLGDNPQTVIDLAVVRPLPRVPQSLPLADALSRMRRINSHLALVTADNGSVVGMVALEDVVEDLVGTMRDGTHR
>NC_020559.1|WP_003899046.1|2081536_2082904_-|HlyC/CorC-family-transporter
MNLTDTVATILAILALTAGTGVFVAAEFSLTALDRSTVEANARGGTSRDRFIQRAHHRLSFQLSGAQLGISITTLATGYLTEPLVAELPHPGLVAVGMSDRVADGLITFFALVIVTSLSMVFGELVPKYLAVARPLRTARSVVAGQVLFSLLLTPAIRLTNGAANWIVRRLGIEPAEELRSARTPQELVSLVRSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIADLVAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEPVAVVPSTLDGDAVMAQVRASALQTAMVVDEYGGTAGMVTLEDLIEEIVGDVRDEHDDATPDVVAAGNGWRVSGLLRIDEVASATGYRAPDGPYETIGGLVLRELGHIPVAGETVELTALDQDGLPDDSMRWLATVIQMDGRRIDLLELIKMGGHADPGSGRGR
>NC_020559.1|WP_003902189.1|2083077_2084517_-|GuaB1-family-IMP-dehydrogenase-related-protein
MMRFLDGHPPGYDLTYNDVFIVPNRSEVASRFDVDLSTADGSGTTIPVVVANMTAVAGRRMAETVARRGGIVILPQDLPIPAVKQTVAFVKSRDLVLDTPVTLAPDDSVSDAMALIHKRAHGVAVVILEGRPIGLVRESSCLGVDRFTRVRDIAVTDYVTAPAGTEPRKIFDLLEHAPVDVAVLTDADGTLAGVLSRTGAIRAGIYTPATDSAGRLRIGAAVGINGDVGAKARALAEAGVDVLVIDTAHGHQVKTLDAIKAVSALDLGLPLAAGNVVSAEGTRDLLKAGANVVKVGVGPGAMCTTRMMTGVGRPQFSAVLECASAARQLGGHIWADGGIRHPRDVALALAAGASNVMIGSWFAGTYESPGDLMRDRDDQPYKESYGMASKRAVVARTGADNPFDRARKALFEEGISTSRMGLDPDRGGVEDLIDHITSGVRSTCTYVGASNLAELHERAVVGVQSGAGFAEGHPLPAGW
>NC_020559.1|WP_003409284.1|2084549_2086001_-|NADP-dependent-phosphogluconate-dehydrogenase
MSSSESPAGIAQIGVTGLAVMGSNIARNFARHGYTVAVHNRSVAKTDALLKEHSSDGKFVRSETIPEFLAALEKPRRVLIMVKAGEATDAVINELADAMEPGDIIIDGGNALYTDTMRREKAMRERGLHFVGAGISGGEEGALNGPSIMPGGPAESYQSLGPLLEEISAHVDGVPCCTHIGPDGSGHFVKMVHNGIEYSDMQLIGEAYQLMRDGLGLTAPAIADVFTEWNNGDLDSYLVEITAEVLRQTDAKTGKPLVDVIVDRAEQKGTGRWTVKSALDLGVPVTGIAEAVFARALSGSVGQRSAASGLASGKLGEQPADPATFTEDVRQALYASKIVAYAQGFNQIQAGSAEFGWDITPGDLATIWRGGCIIRAKFLNHIKEAFDASPNLASLIVAPYFRGAVESAIDSWRRVVSTAAQLGIPTPGFSSALSYYDALRTARLPAALTQAQRDFFGAHTYGRIDEPGKFHTLWSSDRTEVPV
>NC_020559.1|WP_003409298.1|2086030_2086981_-|M56-family-metallopeptidase
MSALAFTILAVLLAGPTPALLARATWPLRAPRAAMVLWQAIALAAVLSSFSAGIAIASRLLMPGPDGRPTTSFVGAAGRLGWPLWAAYITVFALTVLVGARLAVAVVRVATATRRRRAHHRMVVDLVGVGHNGALAQPCARARDLRVLDVAQPLAYCLPGVRSRVVVSEGTLTALADAEVAAILTHERAHLRARHDLVLEAFTAVHAAFPRLVRSANALGAVQLLVELLADDAAVRAAGRTPLARALVACASGRAPSGALAVGGPSTVLRVRRLSGRGNSAVLSAAAYLAAAAVLVVPTVALAVPWLTQLQRLFIA
>NC_020559.1|WP_003409301.1|2086995_2087412_-|transcriptional-repressor-BlaI
MAKLTRLGDLERAVMDHLWSRTEPQTVRQVHEALSARRDLAYTTVMTVLQRLAKKNLVLQIRDDRAHRYAPVHGRDELVAGLMVDALAQAEDSGSRQAALVHFVERVGADEADALRRALAELEAGHGNRPPAGAATET
>NC_020559.1|WP_003899048.1|2087689_2088112_+|PaaI-family-thioesterase
MQPSPDSPAPLNVTVPFDSELGLQFTELGPDGARAQLDVRPKLLQLTGVVHGGVYCAMIESIASMAAFAWLNSHGEGGSVVGVNNNTDFVRSISSGMVYGTAEPLHRGRRQQLWLVTITDDTDRVVARGQVRLQNLEARP
>NC_020559.1|WP_003409305.1|2088160_2088463_+|urease-subunit-gamma
MRLTPHEQERLLLSYAAELARRRRARGLRLNHPEAIAVIADHILEGARDGRTVAELMASGREVLGRDDVMEGVPEMLAEVQVEATFPDGTKLVTVHQPIA
>NC_020559.1|WP_003409308.1|2088459_2088774_+|urease-subunit-beta
MIPGEIFYGSGDIEMNAAALSRLQMRIINAGDRPVQVGSHVHLPQANRALSFDRATAHGYRLDIPAATAVRFEPGIPQIVGLVPLGGRREVPGLTLNPPGRLDR
>NC_020559.1|WP_003899049.1|2088773_2090507_+|urease-subunit-alpha
MARLSRERYAQLYGPTTGDRIRLADTNLLVEVTEDRCGGPGLAGDEAVFGGGKVLRESMGQGRASRADGAPDTVITGAVIIDYWGIIKADIGIRDGRIVGIGKAGNPDIMTGVHRDLVVGPSTEIISGNRRIVTAGTVDCHVHLICPQIIVEALAAGTTTIIGGGTGPAEGTKATTVTPGEWHLARMLESLDGWPVNFALLGKGNTVNPDALWEQLRGGASGFKLHEDWGSTPAAIDTCLAVADVAGVQVALHSDTLNETGFVEDTIGAIAGRSIHAYHTEGAGGGHAPDIITVAAQPNVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLNPRIPEDLAFAESRIRPSTIAAEDVLHDMGAISMIGSDSQAMGRVGEVVLRTWQTAHVMKARRGALEGDPSGSQAADNNRVRRYIAKYTICPAIAHGMDHLIGSVEVGKLADLVLWEPAFFGVRPHVVLKGGAIAWAAMGDANASIPTPQPVLPRPMFGAAAATAAATSVHFVAPQSIDARLADRLAVNRGLAPVADVRAVGKTDLPLNDALPSIEVDPDTFTVRIDGQVWQPQPAAELPMTQRYFLF

Crispr_ID: NC_020559_12

• CRISPR_ID: NC_020559_12
• CRISPR_location: 2159909-2160128
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020559_12

Consensus_repeat	Method
GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	CRISPRCasFinder

spacers of NC_020559_12

>12.1|2159958|122|NC_020559|CRISPRCasFinder
GCGTCGGCAGATTGAACGCACCTAGCGCTGTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCAACTGAGGCAAGTTAAACGCACCTACCGTGATGTTGGCTGGTGTC

CRISPR arrays and Neighbor proteins around NC_020559_12

CRISPR arrays

The CRISPR arrays of NC_020559_12

>merge|NC_020559|12|2159909-2160128|CRISPRCasFinder
GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCAGCGTCGGCAGATTGAACGCACCTAGCGCTGTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCAACTGAGGCAAGTTAAACGCACCTACCGTGATGTTGGCTGGTGTCGTTGTAGCTGGAATCGTCAACGACGGCACCGTCAACCCCGGCAAATCAA

>NC_020559|12|7|2159909-2160128|CRISPRCasFinder
GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	GCGTCGGCAGATTGAACGCACCTAGCGCTGTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCAACTGAGGCAAGTTAAACGCACCTACCGTGATGTTGGCTGGTGTC
GTTGTAGCTGGAATCGTCAACGACGGCACCGTCAACCCCGGCAAATCAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_003900433.1|2166267_2167608_+|lipase-LipD	unknown	unknown	gnl|CDD|365903
NC_020559.1|WP_003409667.1|2165161_2166277_+|serine-hydrolase	unknown	unknown	gnl|CDD|224594
NC_020559.1|WP_003409685.1|2170767_2171541_+|YqjF-family-protein	unknown	unknown	gnl|CDD|225897
NC_020559.1|WP_003899074.1|2144114_2144762_-|DUF4262-domain-containing-protein	unknown	unknown	gnl|CDD|379457
NC_020559.1|WP_003409584.1|2151342_2153643_+|isocitrate-lyase-family-protein	unknown	unknown	gnl|CDD|215482
NC_020559.1|WP_003409574.1|2150070_2150823_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293840
NC_020559.1|WP_003900434.1|2167644_2168025_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003409568.1|2148261_2148867_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl|CDD|224793
NC_020559.1|WP_003900428.1|2143304_2143775_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003409577.1|2150800_2151208_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003899079.1|2148966_2149971_-|zinc-binding-dehydrogenase	unknown	unknown	gnl|CDD|176236
NC_020559.1|WP_003409680.1|2168181_2170044_+|AMP-binding-protein	unknown	unknown	gnl|CDD|171527
NC_020559.1|WP_003409666.1|2163618_2164890_-|haloacid-dehalogenase-like-hydrolase	unknown	unknown	gnl|CDD|273654
NC_020559.1|WP_003409684.1|2170051_2170531_-|immunoprotective-protein-Mpt63	unknown	unknown	gnl|CDD|370335
NC_020559.1|WP_003899076.1|2147028_2147472_-|transcriptional-repressor	unknown	unknown	gnl|CDD|223806
NC_020559.1|WP_003409689.1|2172334_2172979_-|TIGR03085-family-protein	unknown	unknown	gnl|CDD|132129
NC_020559.1|WP_003409566.1|2147585_2148179_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl|CDD|224793
NC_020559.1|WP_031649703.1|2162717_2163581_+|acyltransferase-family-protein	unknown	unknown	gnl|CDD|153249
NC_020559.1|WP_003899082.1|2162155_2162620_-|SRPBCC-family-protein	unknown	unknown	gnl|CDD|176863
NC_020559.1|WP_003899075.1|2144768_2146991_-|catalase/peroxidase-HPI	unknown	unknown	gnl|CDD|237891

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_003900433.1|2166267_2167608_+|lipase-LipD	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	7.07573e-54
NC_020559.1|WP_003409667.1|2165161_2166277_+|serine-hydrolase	gnl|CDD|224594	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms].	8.61879e-60
NC_020559.1|WP_003409685.1|2170767_2171541_+|YqjF-family-protein	gnl|CDD|225897	COG3361, COG3361, Uncharacterized conserved protein [Function unknown].	4.52786e-127
NC_020559.1|WP_003899074.1|2144114_2144762_-|DUF4262-domain-containing-protein	gnl|CDD|379457	pfam14081, DUF4262, Domain of unknown function (DUF4262). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are typically between 147 and 227 amino acids in length. Some members may be incorrectly annotated as the KatG protein.	8.55531e-31
NC_020559.1|WP_003409584.1|2151342_2153643_+|isocitrate-lyase-family-protein	gnl|CDD|215482	PLN02892, PLN02892, isocitrate lyase.	2.96208e-144
NC_020559.1|WP_003409574.1|2150070_2150823_+|MBL-fold-metallo-hydrolase	gnl|CDD|293840	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	1.95555e-42
NC_020559.1|WP_003409684.1|2170051_2170531_-|immunoprotective-protein-Mpt63	gnl|CDD|370335	pfam09167, DUF1942, Domain of unknown function (DUF1942). Members of this family of bacterial proteins assume a beta-sandwich structure consisting of two antiparallel beta-sheets similar to an immunoglobulin-like fold, with an additional small, antiparallel beta-sheet. The longer-stranded beta-sheet is made up of four antiparallel beta-strands. The shorter-stranded beta-sheet consists of five beta-strands, four of these beta-strands form an antiparallel beta-sheet. The exact function of this family of proteins is unknown, though a putative role includes involvement in host-bacterial interactions involved in endocytosis or phagocytosis, possibly during bacterial internalisation.	3.87872e-58
NC_020559.1|WP_003409568.1|2148261_2148867_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl|CDD|224793	COG1881, COG1881, Phospholipid-binding protein [General function prediction only].	1.29998e-51
NC_020559.1|WP_003899079.1|2148966_2149971_-|zinc-binding-dehydrogenase	gnl|CDD|176236	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.26124e-152
NC_020559.1|WP_003409680.1|2168181_2170044_+|AMP-binding-protein	gnl|CDD|171527	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional.	0
NC_020559.1|WP_003409666.1|2163618_2164890_-|haloacid-dehalogenase-like-hydrolase	gnl|CDD|273654	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490. This hypothetical equivalog is a member of the IB subfamily (TIGR01488) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The sequences modelled here are all bacterial. The IB subfamily includes the enzyme phosphoserine phosphatase (TIGR00338). Due to this relationship, several of these sequences have been annotated as "phosphoserine phosphatase related proteins," or "Phosphoserine phosphatase-family enzymes." There is presently no evidence that any of the enzymes in this model possess PSPase activity. OMNI|NTL01ML1250 is annotated as a "possible transferase," however this is due to the C-terminal domain found on this sequence which is homologous to a group of glycerol-phosphate acyltransferases (between trusted and noise to TIGR00530). A subset of these sequences including OMNI|CC1962, the Caulobacter crescentus CicA protein cluster together and may represent a separate equivalog. [Unknown function, Enzymes of unknown specificity].	4.7592e-11
NC_020559.1|WP_003899082.1|2162155_2162620_-|SRPBCC-family-protein	gnl|CDD|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	1.38133e-21
NC_020559.1|WP_003899076.1|2147028_2147472_-|transcriptional-repressor	gnl|CDD|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	4.92282e-41
NC_020559.1|WP_003409689.1|2172334_2172979_-|TIGR03085-family-protein	gnl|CDD|132129	TIGR03085, TIGR03085, TIGR03085 family protein. This family, like pfam07398 and TIGRFAMs family TIGR03084, belongs to the larger set of probable enzymes defined in family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized. [Hypothetical proteins, Conserved].	8.20015e-78
NC_020559.1|WP_003409566.1|2147585_2148179_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl|CDD|224793	COG1881, COG1881, Phospholipid-binding protein [General function prediction only].	4.33831e-50
NC_020559.1|WP_031649703.1|2162717_2163581_+|acyltransferase-family-protein	gnl|CDD|153249	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.	3.60613e-63
NC_020559.1|WP_003899075.1|2144768_2146991_-|catalase/peroxidase-HPI	gnl|CDD|237891	PRK15061, PRK15061, catalase/peroxidase.	0

Protein sequences

>NC_020559.1|WP_003409584.1|2151342_2153643_+|isocitrate-lyase-family-protein
MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADADTGHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFYELGVKELNGHLLYALGDSEYAAAGGWLERQGIFGLVSDAVNAWREDGQQSIDGIFDQVESRFVAAWEDDAGLMTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRTILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTEVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA
>NC_020559.1|WP_003409577.1|2150800_2151208_-|hypothetical-protein
MVLSRTSTGRVILVPTQLRFDRWFLPLAVPLGLGPKNSELWVGAGSLHVKMGWAFAADIPLTSITKAEATNARVYAAGVHFGFGRWLVNGSRKGLVALTIDPPEQAKMWKKSMTVRELWVSVTDPDALVTACTAK
>NC_020559.1|WP_003409574.1|2150070_2150823_+|MBL-fold-metallo-hydrolase
MHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR
>NC_020559.1|WP_003899079.1|2148966_2149971_-|zinc-binding-dehydrogenase
MRAVVITKHGDPSVLQVRQRPDPPPPGPGQLRVAVRAAGVNFADHLARVGLYPDAPKLPAVVGYEVAGTVEAVGDGVDPNRVGERVLAGTRFGGYCEIVNVAATDSVVLPDALSFEQGAAVPVNYATAWAALHGYGSLRAGERVLIHAAAGGVGIAAVQFAKAAKAEVHGTASPQKHQKLAEFGVDRAIDYRRDGWWQGLGPYDVVLDALGGTSLRRSYTLLRPGGRLVGYGISNMQHGEKRSMRRVAPHALSMLRGFNLMKQLEESKTVIGLNMLRLWDDRRTLEPWIAPLTKALNDGTILPIVHAIVPFAEAPEAHRILAARENVDKVVLVP
>NC_020559.1|WP_003409568.1|2148261_2148867_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MTSTLHRTPLATAGLALVVALGGCGGGGGDSRETPPYVPKATTVDATTPAPAAEPLTIASPMFADGAPIPVQFSCKGANVAPPLTWSSPAGAAELALVVDDPDAVGGLYVHWIVTGIAPGSGSTADGQTPAGGHSVPNSGGRQGYFGPCPPAGTGTHHYRFTLYHLPVALQLPPGATGVQAAQAIAQAASGQARLVGTFEG
>NC_020559.1|WP_003409566.1|2147585_2148179_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MAHAFHRFALAILGLALPVALVAYGGNGDSRKAAPLAPKAAALGRSMPETPTGDVLTISSPAFADGAPIPEQYTCKGANIAPPLTWSAPFGGALVVDDPDAPREPYVHWIVIGIAPGAGSTADGETPGGGISLPNSSGQPAYTGPCPPAGTGTHHYRFTLYHLPAVPPLAGLAGTQAARVIAQAATMQARLIGTYEG
>NC_020559.1|WP_003899076.1|2147028_2147472_-|transcriptional-repressor
MSSIPDYAEQLRTADLRVTRPRVAVLEAVNAHPHADTETIFGAVRFALPDVSRQAVYDVLHALTAAGLVRKIQPSGSVARYESRVGDNHHHIVCRSCGVIADVDCAVGEAPCLTASDHNGFLLDEAEVIYWGLCPDCSISDTSRSHP
>NC_020559.1|WP_003899075.1|2144768_2146991_-|catalase/peroxidase-HPI
MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDIEEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLSWADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPDPMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVVWTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEHPEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAASSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAGHNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKRLPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKFVQDFVAAWDKVMNLDRFDVR
>NC_020559.1|WP_003899074.1|2144114_2144762_-|DUF4262-domain-containing-protein
MIGPARRSTTTRRSTPRADRLAGCWCLPGAICQTPRAWWSQARRDGDDETGMRRKGAEMCWMCDHPEATAEEYLDEVYGIMLMHGWAVQHVECERRPFAYTVGLTRRGLPELVVTGLSPRRGQRLLNIAARRALVGDLLTPGMQTTLPAGPLVETVQVTHPDAHLYCAIAIFGDKVTALQLVWADRRGRWPWAADFDEGRGTQPVLGMRATRRSA
>NC_020559.1|WP_003900428.1|2143304_2143775_-|hypothetical-protein
MRLKPAPSPAAAFAVAGLILAGWAGSVGLAGADPEPAPTPKTAIDSDGTYAVGIDIAPGTYSSAGPVGDGTCYWKRMGNPDGALIDNALSKKPQVVTIEPTDKAFKTHGCQPWQNTGSEGAAPAGVPGPEAGAQLQNQLGILNGLLGPTGGRVPQP
>NC_020559.1|WP_003899082.1|2162155_2162620_-|SRPBCC-family-protein
MSGRKFSFEVTKTSSAPAATLFRLVTDGGNWATWAKPIVAQSSWARRGDPAPGGIGAIRKLGMWPVFVQEETVEYEQDRRHVYKLVGARTPVQDYFGEVVLTPNASGGTDLRWSGSFTEKVRGTGPVMRAALGGAVRFFAGQLVKAAEREAVRR
>NC_020559.1|WP_031649703.1|2162717_2163581_+|acyltransferase-family-protein
MFPRWPQQAHNHEVSRADTVSVPRAPTQAEVAAVLRIMTPLRKVIKPKVYGIENVPTERALLVGNHNTLGLVDAPLLAAELWERGRIVRSLGDHAHFKIPGWRDALTRTGVVEGTREITSELMRRGELVMVFPGGAREVNKRKNERYKLVWKNRLGFARLAIQHGYPIVPFASVGAEHGIDIVLDNESPLLAPVQFLAEKLLGTKDGPALVRGVGLTPVPRPERQYYWFGEPTDTTEFMGQQADDNAARRVRERAAAAIEHGIELMLAERAADPNRSLVGRLLRSDA
>NC_020559.1|WP_003409666.1|2163618_2164890_-|haloacid-dehalogenase-like-hydrolase
MVRLIPSLLAMATVLGGVIGCSAHQPPTPASGCRQLDAFLKWHHGVREFLQSAIDANSRCTGTADGSARKVAIFDWDNTVVKNDIGYATNYYMLQHSLVLQPANQDWHAASRYLTDAAANALSVACGKVVPAGKPLPTGSNALCANEILSLLDGETTTGQPAFVGNNVRRLAGPYAWSNALSAGYTAEELAGFADQAKKQNLAADVGATQQVGTQQVDGYIRVYPQMKDLIGTLQAHGIDTWVVSASPEPIVKVWAGEVGLDDQHVVGVRSVADQSGKLTAHLVGCGGVRDGDDSVMTYLDGKRCWANQVIFGVTGPQAFNQLAADRRQVLAAGDSNSDATFVGDATVVSLVINRNQDDLMCRAYDGLFTRGGKWAINPMFIDPLPQHAPYVCGEAFINPDGSKQPVLRNDGTPIPDQVDSVF
>NC_020559.1|WP_003409667.1|2165161_2166277_+|serine-hydrolase
MDSTVTASIRRMLGLLAATLLLGGCTGQHTTRTAASTTYTPHIKASSQDVLDGAINADEPGCSAAVGVEGKVIWSGVRGIADLASGAKITTDTVFDIASVSKQFTATAILLLVEAGKLTLDDPISQYVPELPDWAQTVTVEQLMHQTSGIPDYVALLAARGYQVSDRTIEAEARQALAAAPELQFKPGTRFDYSNSNYLLLGEIVHRASGQPLPEFLSAEIFQPLGLAMVVDPVGKVPNKAVSYEKGTGGNRSEYRVGNPAWEQIGDGGIQTTPSQLARWADNYRTGSVGGLKLLEAQLAGAVETEPGGGDRYGAGIVSRADGTLDHAGAWAGFVTAFHISSDRRTSVAISCNTDKPDPVAMADALGRLWM
>NC_020559.1|WP_003900433.1|2166267_2167608_+|lipase-LipD
MDVAGLPRLAAGTQAAIIHGMAQPPSLLTTDNGLPFGVQGACDSRFTGVIRAFAGLYPGRKFGGGALSVYIDGRQVVDVWTGWSDRQGKVPWTADTGAMVFSATKGLAATVIHRLVDRGLLSYDAPVAEYWPEFGANGKSEVTVSDVLRHRSGLAHLKGVDKDEVMDHLLMEQKLAAAPLDRQHGKLAYHAVTYGWLLSGLARAVTGKGMRELFREELARPLNTDGIHLGRPPADSPTKAAQTLLPQAKVPTPLLDFIAPKVAGLSFSGLLGAVYFPGILSLLQDDMPFLDGEVPAVNGVVTARALAKTYGALANDGVIDGTRLLSSQAVRGLTGKSELWPDLNLGLPFTYHQGYQSSPVPGLLEGYGHIGLGGTIGWADPETGSAFGYVHNRLLTLLLFDIGSFAGLAALLNSAVVAARRDDPLEVPHFGAPYSEPRHEQAASGA
>NC_020559.1|WP_003900434.1|2167644_2168025_-|hypothetical-protein
MDPADVINPTSTRDAALARVLAYRQRVRARPLLIRATLAVVGGGLFVVSLPMIVLLPELGIPALLVAFRLLAVEAQWAVRAYAWTDWRFTQLREWFHRQVLVTRAAILVGLFLAAVALVWLLVYEF
>NC_020559.1|WP_003409680.1|2168181_2170044_+|AMP-binding-protein
MNDGSRQELRVRSGLLQIEDCLDADGGIALPAGTTLISLIERNIKYVGDLVAYRYLDHARSAAGCALEVTWTQFGMRLAAIGAHVQRFAGPGDRVAILAPQGIDYVCGFYAAIKAGTVAVPLFAPELPGHAERLDTALRDSEPAVILTTAAAKNAVEGFLNNVPRLRKPTVLVIDQIPDREGELFVPVELDIDAVSHLQYTSGSTRPPVGVEITHRAVGTNLVQMILSIDLLNRNTHGVSWLPLYHDMGLSMIGFPAVYGGHSTLMSPTAFVRRPLRWIQALSEGSRTGRVVTAAPNFAYEWAAQRGLPAQGDDVDLSNVVLIIGSEPVSIDAVTTFNKAFAPYGLPRTAFKPSYGIAEATLLVATIDHAAEPTVVYLDPEQLGAGHATRVAPDAPNAVVHVSCGHVARSLWAVIVDPDTGPEAGAELPDGEIGEVWLQGDNVARGYWGRPEETRMTFGARLQSPLAEGSHADGSAIDDTWLRTGDLGVYLDGELYITGRIADLLTIDGRNHYPQDIEATAAEASPMVRRGYITAFTVPASDGDDRNQRLVIIAERAAGTSRSDPRPALDAIRAAVCNRHGLSVADLSFLPAGAIPRTTSGKLARQACRAQYLSGRLGVH
>NC_020559.1|WP_003409684.1|2170051_2170531_-|immunoprotective-protein-Mpt63
MKLTTMIKTAVAVVAMAAIATFAAPVALAAYPITGKLGSELTMTDTVGQVVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVSQFNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTIVAMNNGMEDLLIWEP
>NC_020559.1|WP_003409685.1|2170767_2171541_+|YqjF-family-protein
MTAIPGPSGAEPGESRALAGYPVTPPALPRPVIFDQRWTDLTFIHWPVLPESVAGSYPPGTRPDVFADGMTYVGLVPFRMSSTKLGTALPIPYVGTFPETNVRLYSIDNAGRHGVLFRSLETARLTVVPLTRIGLGIPYAWSRMRMMRSGKHITYHSVRRWPRRGLRSLLTITIGDLVEPTPLEVWLTARWGAHTRKAGRTWWVPNEHKPWPLRAAEIAELNDELIDASGVQPTGDRLRALFSPGVHARFGRPCVVQ
>NC_020559.1|WP_003409689.1|2172334_2172979_-|TIGR03085-family-protein
MADVPLDAQERLELCDLLEELGPAVATLIEGWTAHDLAAHIVLRERDLVAGLCIVLPGPFQRFAERRRARLAQSKDFTWLVARIRSGPPMGFFRIGWVRTLANLNEFFVHHEDVRRASGRGPRSLTPEMDAALWRNVRRGSHFLSRRLHGCGLEIEWVGTGKRVRVRSGEPTARLTGPPGELLLYVFGRRAVARVEVSGPLEAIAAVHRTHFGM

Crispr_ID: NC_020559_13

• CRISPR_ID: NC_020559_13
• CRISPR_location: 3105878-3106794
• CRISPR_type: TypeIII
• Repeat_type: II-B,III-A
• Spacer_info: 12 spacers
• Cas_protein_info: cas2,cas1,csm4gr5,csm3gr7,csm2gr11,cas10,cas6

Consensus repeat of NC_020559_13

Consensus_repeat	Method
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	PILER-CR
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CRISPRCasFinder
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CRT

spacers of NC_020559_13

>13.1|3105914|38|NC_020559|PILER-CR,CRISPRCasFinder,CRT
TCGGGCACGGCCGAAACACCGCGCGAAGGGCGGTTCAA
>13.2|3105988|40|NC_020559|PILER-CR,CRISPRCasFinder,CRT
TGGGAGGATGTCACTCGGACATAGCTGTCATCGGCGGTGT
>13.3|3106064|40|NC_020559|PILER-CR,CRISPRCasFinder,CRT
ATGGAGCAGTAGCGTGGCTGTGGTGTGGCGGGCGATATGC
>13.4|3106140|37|NC_020559|PILER-CR,CRISPRCasFinder,CRT
TGCTGCACCTCCCGCACCCGGTGCGATTCTGCGTCCA
>13.5|3106213|36|NC_020559|PILER-CR,CRISPRCasFinder,CRT
CCCGATAGTCGCGCTCGTCCATGTCCCACCATGAGG
>13.6|3106285|35|NC_020559|PILER-CR,CRISPRCasFinder,CRT
TACCTGATAGAAGCCGGAAAGCTCCGTGCCGTCAG
>13.7|3106356|38|NC_020559|PILER-CR,CRISPRCasFinder,CRT
AGGGCACTGGACCTGTATGAGGCACAGATGGCGTACTA
>13.8|3106430|40|NC_020559|PILER-CR,CRISPRCasFinder,CRT
CCGGATCGGTTACCCACGCCGATTTACTGGCCATCGTCGG
>13.9|3106506|35|NC_020559|PILER-CR,CRISPRCasFinder,CRT
ACTTGCGCGCACAACGCATCCGCCATCCACGGGGC
>13.10|3106577|37|NC_020559|PILER-CR,CRISPRCasFinder,CRT
CTGAAAGGGGGACTGTGGACGAGTTCGCGCTCAAAAT
>13.11|3106650|38|NC_020559|PILER-CR,CRISPRCasFinder,CRT
TTGAACACGCCGATACCTATTTGGTCGGGAGTGATAAA
>13.12|3106724|35|NC_020559|CRISPRCasFinder,CRT
TGACAGGGTGCGGTGGTCGCTGATCGGCTCCCCGA

CRISPR arrays and Neighbor proteins around NC_020559_13

CRISPR arrays

The CRISPR arrays of NC_020559_13

>merge|NC_020559|13|3105878-3106794|PILER-CR,CRISPRCasFinder,CRT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTCGGGCACGGCCGAAACACCGCGCGAAGGGCGGTTCAAGTTTCCGTCCCCTCTCGTGGTTTTGGGTCTGACGACTGGGAGGATGTCACTCGGACATAGCTGTCATCGGCGGTGTGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGAGGACATGGAGCAGTAGCGTGGCTGTGGTGTGGCGGGCGATATGCGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTGCTGCACCTCCCGCACCCGGTGCGATTCTGCGTCCAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCCGACGACCCCGATAGTCGCGCTCGTCCATGTCCCACCATGAGGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTACCTGATAGAAGCCGGAAAGCTCCGTGCCGTCAGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACAGGGCACTGGACCTGTATGAGGCACAGATGGCGTACTAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCCGGATCGGTTACCCACGCCGATTTACTGGCCATCGTCGGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACTTGCGCGCACAACGCATCCGCCATCCACGGGGCGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTGAAAGGGGGACTGTGGACGAGTTCGCGCTCAAAATGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTTGAACACGCCGATACCTATTTGGTCGGGAGTGATAAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTGACAGGGTGCGGTGGTCGCTGATCGGCTCCCCGAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACTGA

>NC_020559|13|5|3105878-3106723|PILER-CR
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TCGGGCACGGCCGAAACACCGCGCGAAGGGCGGTTCAA
GTTTCCGTCCCCTCTCGTGGTTTTGGGTCTGACGAC	TGGGAGGATGTCACTCGGACATAGCTGTCATCGGCGGTGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGAGGAC	ATGGAGCAGTAGCGTGGCTGTGGTGTGGCGGGCGATATGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGCTGCACCTCCCGCACCCGGTGCGATTCTGCGTCCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCCGACGAC	CCCGATAGTCGCGCTCGTCCATGTCCCACCATGAGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TACCTGATAGAAGCCGGAAAGCTCCGTGCCGTCAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	AGGGCACTGGACCTGTATGAGGCACAGATGGCGTACTA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGGATCGGTTACCCACGCCGATTTACTGGCCATCGTCGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACTTGCGCGCACAACGCATCCGCCATCCACGGGGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTGAAAGGGGGACTGTGGACGAGTTCGCGCTCAAAAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TTGAACACGCCGATACCTATTTGGTCGGGAGTGATAAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC

>NC_020559|13|8|3105878-3106794|CRISPRCasFinder
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TCGGGCACGGCCGAAACACCGCGCGAAGGGCGGTTCAA
GTTTCCGTCCCCTCTCGTGGTTTTGGGTCTGACGAC	TGGGAGGATGTCACTCGGACATAGCTGTCATCGGCGGTGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGAGGAC	ATGGAGCAGTAGCGTGGCTGTGGTGTGGCGGGCGATATGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGCTGCACCTCCCGCACCCGGTGCGATTCTGCGTCCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCCGACGAC	CCCGATAGTCGCGCTCGTCCATGTCCCACCATGAGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TACCTGATAGAAGCCGGAAAGCTCCGTGCCGTCAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	AGGGCACTGGACCTGTATGAGGCACAGATGGCGTACTA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGGATCGGTTACCCACGCCGATTTACTGGCCATCGTCGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACTTGCGCGCACAACGCATCCGCCATCCACGGGGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTGAAAGGGGGACTGTGGACGAGTTCGCGCTCAAAAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TTGAACACGCCGATACCTATTTGGTCGGGAGTGATAAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGACAGGGTGCGGTGGTCGCTGATCGGCTCCCCGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACTGA

>NC_020559|13|2|3105878-3106794|CRT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TCGGGCACGGCCGAAACACCGCGCGAAGGGCGGTTCAA
GTTTCCGTCCCCTCTCGTGGTTTTGGGTCTGACGAC	TGGGAGGATGTCACTCGGACATAGCTGTCATCGGCGGTGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGAGGAC	ATGGAGCAGTAGCGTGGCTGTGGTGTGGCGGGCGATATGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGCTGCACCTCCCGCACCCGGTGCGATTCTGCGTCCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCCGACGAC	CCCGATAGTCGCGCTCGTCCATGTCCCACCATGAGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TACCTGATAGAAGCCGGAAAGCTCCGTGCCGTCAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	AGGGCACTGGACCTGTATGAGGCACAGATGGCGTACTA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGGATCGGTTACCCACGCCGATTTACTGGCCATCGTCGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACTTGCGCGCACAACGCATCCGCCATCCACGGGGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTGAAAGGGGGACTGTGGACGAGTTCGCGCTCAAAAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TTGAACACGCCGATACCTATTTGGTCGGGAGTGATAAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGACAGGGTGCGGTGGTCGCTGATCGGCTCCCCGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACTGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_003414288.1|3115763_3116672_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl|CDD|224483
NC_020559.1|WP_003414190.1|3102100_3102412_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003917684.1|3099157_3099412_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003414276.1|3110046_3110388_-|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|224262
NC_020559.1|WP_003899491.1|3104916_3105729_+|ExeA-family-protein	unknown	unknown	gnl|CDD|225806
NC_020559.1|WP_003899489.1|3101738_3101996_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003900580.1|3117743_3120182_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	COG1353_cas10_CAS-III	gnl|CDD|187811
NC_020559.1|WP_003414198.1|3103510_3104920_+|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NC_020559.1|WP_003414296.1|3117372_3117747_-|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl|CDD|273844
NC_020559.1|WP_003899488.1|3100350_3101505_+|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NC_020559.1|WP_087902221.1|3111661_3112923_-|IS3-like-element-IS987-family-transposase	unknown	unknown	gnl|CDD|222853
NC_020559.1|WP_003414292.1|3116652_3117363_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187815
NC_020559.1|WP_003414184.1|3099960_3100152_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003414195.1|3102831_3103440_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_009938577.1|3099559_3099964_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003414279.1|3110388_3111405_-|CRISPR-associated-endonuclease-Cas1	cas1	COG1518_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|272998
NC_020559.1|WP_087902221.1|3113615_3114877_-|IS3-like-element-IS987-family-transposase	unknown	unknown	gnl|CDD|222853
NC_020559.1|WP_087902221.1|3106833_3108095_-|IS3-like-element-IS987-family-transposase	unknown	unknown	gnl|CDD|222853
NC_020559.1|WP_003912014.1|3120178_3120901_-|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl|CDD|227838
NC_020559.1|WP_003911993.1|3098706_3098982_+|DUF1778-domain-containing-protein	unknown	unknown	gnl|CDD|226860

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_020559.1|WP_003414288.1|3115763_3116672_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	1.3e-98	324.8	0.0
NC_020559.1|WP_003414292.1|3116652_3117363_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	6.2e-81	265.9	0.0
NC_020559.1|WP_003414276.1|3110046_3110388_-|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	5.6e-26	85.5	0.1
NC_020559.1|WP_003414279.1|3110388_3111405_-|CRISPR-associated-endonuclease-Cas1	cas1	COG1518_cas1_CAS-I:CAS-II:CAS-III	1e-108	357.9	0.0
NC_020559.1|WP_003912014.1|3120178_3120901_-|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	9.8e-88	288.8	0.1
NC_020559.1|WP_003900580.1|3117743_3120182_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	COG1353_cas10_CAS-III	1.9e-238	788.5	0.0
NC_020559.1|WP_003414296.1|3117372_3117747_-|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	2.1e-23	77.8	0.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_003414288.1|3115763_3116672_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl|CDD|224483	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.37381e-109
NC_020559.1|WP_003414198.1|3103510_3104920_+|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	7.41102e-28
NC_020559.1|WP_003414276.1|3110046_3110388_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	3.66595e-25
NC_020559.1|WP_003899491.1|3104916_3105729_+|ExeA-family-protein	gnl|CDD|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	3.94464e-110
NC_020559.1|WP_003900580.1|3117743_3120182_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl|CDD|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
NC_020559.1|WP_003899488.1|3100350_3101505_+|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.94329e-16
NC_020559.1|WP_003414296.1|3117372_3117747_-|type-III-A-CRISPR-associated-protein-Csm2	gnl|CDD|273844	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2. These proteins are found adjacent to a characteristic short, palidromic repeat cluster termed CRISPR, a probable mobile DNA element. This model represents the C-terminal domain of a minor family of CRISPR-associated protein from the Mtube subtype of CRISPR/Cas locus. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2.	4.56134e-21
NC_020559.1|WP_087902221.1|3111661_3112923_-|IS3-like-element-IS987-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.28492e-102
NC_020559.1|WP_003414292.1|3116652_3117363_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl|CDD|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	4.36536e-99
NC_020559.1|WP_087902221.1|3113615_3114877_-|IS3-like-element-IS987-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.28492e-102
NC_020559.1|WP_003414279.1|3110388_3111405_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|272998	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1. This model identifies CRISPR-associated protein Cas1, the most universal CRISPR system protein. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Cas1 is a metal-dependent DNA-specific endonuclease.	2.72742e-113
NC_020559.1|WP_087902221.1|3106833_3108095_-|IS3-like-element-IS987-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.28492e-102
NC_020559.1|WP_003912014.1|3120178_3120901_-|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.14295e-72
NC_020559.1|WP_003911993.1|3098706_3098982_+|DUF1778-domain-containing-protein	gnl|CDD|226860	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown].	1.95042e-26

Protein sequences

>NC_020559.1|WP_003899491.1|3104916_3105729_+|ExeA-family-protein
MMHKLISYYGFSRMPFGRDLAPGMLHRHSAHNEAVARIGWCIADRRIGVITGEVGAGKTVAVRAALASLDRSRHTIIYLPDPTVGVQGIHHRIVASLGGQPLTHHATLAPQAADALAAEQAERGRTPVVVVEEAHLLGYDQLEALRLLTNHDLDSSSPFACLLIGQPTLRRRMKLGVLAALDQRIGLRYAMPPMTDTNTGSYLRHHLKLAGRDDALFSDDAIGLIHQTSRGYPRAVNNLALQALVAAFAADKAIVDESTTRTAIAEVTAD
>NC_020559.1|WP_003414198.1|3103510_3104920_+|DDE-type-integrase/transposase/recombinase
MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQRGKMVRELASREHTDPFGRRVRISRQTIDRWIRGWRAGGFDALVPNPRQCTPRTPAEVLELAVALRRENPQRTAAAIRRILRTQLGWAPDERTLQRNFHRLGLTGATTGSAPAVFGRFEAEHPNALWTGDVLHGIRIDLRKTYLFAFLDDHSRLVPGYRWGHAEDTVRLAAALRPALASRGVPNAVYVDNGSPYVDAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFLVEITGEPDVVGRHYVADLAELNRLFTAWVETVYHRSVHSETGQTPLARWSAGGPIPLPAPETLTEAFLWEEHRRVTKTATVSLHGNRYEIDPALVGRKVELVFDPFDLTRIEVRLAGAPMGRAIPYHIGRHSHPKAKPETPTAPPKPSGIDYAQLIETAHAAELARGVNYTALTGAADQIPGQLDLLTGQEAQPK
>NC_020559.1|WP_003414195.1|3102831_3103440_+|hypothetical-protein
MVTVEADVDQVERRLAAGELSCPSCGGVLAGWGRARSRQLRGPAGPVELCPRRSRCTGCGVTHVLLPVSALLRRADTAAVIVSALAAKATSRVGFRRIATDVARPAETVRGWLRRFAERVEAVRSVFTVWLCAVDADPVMPDAGGGGFVDAVVAIGALAAAIGRRFSLPTVSLAETAVAVSGGRLLAPGWPGEWVQHESTLP
>NC_020559.1|WP_003414190.1|3102100_3102412_+|hypothetical-protein
MTYAARDDTTLPKLLAQMRWVVLVDKRQLAVLLLENEGPVASATDTLDTRGDSDYENQPVDAVERLCRRLADQAVRQWGFMQGLKQKLGPGVDVRMKLVEWNR
>NC_020559.1|WP_003899489.1|3101738_3101996_+|hypothetical-protein
MSNVLDAISTEHRPVIEQELENRNPALFDELRRTEKPTNEQSDAVIDVLSDALMKTFGPDWVPNDYGLKIERAIDAYLETWPIYR
>NC_020559.1|WP_003899488.1|3100350_3101505_+|DDE-type-integrase/transposase/recombinase
MVSTTGMGRSTARRMLTGPGLPEPAEQVDGRRLRARGFSDDARALLEHVWALMGMPCGKYLVVMLELWLPLVAAAGDLDKPFATEAAVAELKAMSAATVDRYLKPARERMRIKGISTTKPSPLLRNSITIHTCSDEAPKVPGVIEADTVAHCGPSLIGEFARTLTMTDLVTGWTENASIRNNAAKWILEGIKECQQRFPFPMTVFDSDCGGEFINHDVAGWLQARDIAQTRSRPYQKNDQAHVESKNNHVVRKHAFYWRYDTGEELELLNRLWPLVSLRCNFFTPTKKPVGYTSTVNGRRKRIYDKPATPWQRLQASGVLDAQQLSTVAARIEGFNPADLTRQINAIQMQLLDLAKTKTEALATARHIDLQSLQPSINRLAKAK
>NC_020559.1|WP_003414184.1|3099960_3100152_+|hypothetical-protein
MKTNPRYGPAFYSVMTVLFLALFVLNVCTHGSTLGLISTGGLAVLMGYIGYRGWSGKRHINRQ
>NC_020559.1|WP_009938577.1|3099559_3099964_+|hypothetical-protein
MGRGNGKILDPVVATTGMGRSTARQMLTGPRLPGPAEQVDGRSLRPRGFSDEARALLEHVWALMGMPCGKYLVVMHDLWLPLLTAAGDLDKPLVTEASVAELKATALPGANRMPHWAAGTLPDGFPARAVRTRT
>NC_020559.1|WP_003917684.1|3099157_3099412_-|hypothetical-protein
MTVELGGAVVDGVDDQGAGAVVPGTGHGSDEGIEEKIATETGALLLPVERQASEDEHWDRVGSGWPRPGRDGTRIRSMLPMASA
>NC_020559.1|WP_003911993.1|3098706_3098982_+|DUF1778-domain-containing-protein
MPETLTGRLNFRLSPEQEQALRHAAALTGQSLSGFVLSAAVDHAHDLLARANRIELSEAAFRRFVAALDEPDEAAPELVRLARRKSRIPPH
>NC_020559.1|WP_087902221.1|3106833_3108095_-|IS3-like-element-IS987-family-transposase
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_020559.1|WP_003414276.1|3110046_3110388_-|CRISPR-associated-endonuclease-Cas2
MPTRSREEYFNLPLKVDESSGTIGKMFVLVIYDISDNRRRASLAKILAGFGYRVQESAFEAMLTKGQLAKLVARIDRFAIDCDNIRIYKIRGVAAVTFYGRGRLVSAEEFVFF
>NC_020559.1|WP_003414279.1|3110388_3111405_-|CRISPR-associated-endonuclease-Cas1
MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHRYTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA
>NC_020559.1|WP_087902221.1|3111661_3112923_-|IS3-like-element-IS987-family-transposase
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_020559.1|WP_087902221.1|3113615_3114877_-|IS3-like-element-IS987-family-transposase
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_020559.1|WP_003414288.1|3115763_3116672_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRLTDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLKGISALGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPESAA
>NC_020559.1|WP_003414292.1|3116652_3117363_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MTTSYAKIEITGTLTVLTGLQIGAGDGFSAIGAVDKPVVRDPLSRLPMIPGTSLKGKVRTLLSRQYGADTETFYRKPNEDHAHIRRLFGDTEEYMTGRLVFRDTKLTNKDDLEARGAKTLTEVKFENAINRVTAKANLRQMERVIPGSEFAFSLVYEVSFGTPGEEQKASLPSSDEIIEDFNAIARGLKLLELDYLGGSGTRGYGQVKFSNLKARAAVGALDGSLLEKLNHELAAV
>NC_020559.1|WP_003414296.1|3117372_3117747_-|type-III-A-CRISPR-associated-protein-Csm2
MSVIQDDYVKQAEVIRGLPKKKNGFELTTTQLRVLLSLTAQLFDEAQQSANPTLPRQLKEKVQYLRVRFVYQSGREDAVKTFVRNAKLLEALEGIGDSRDGLLRFCRYMEALAAYKKYLDPKDK
>NC_020559.1|WP_003900580.1|3117743_3120182_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MNPQLIEAIIGCLLHDIGKPVQRAALGYPGRHSAIGRAFMKKVWLRDSRNPSQFTDEVDEADIGVSDRRILDAISYHHSSALRTAAENGRLAADAPAYIAYIADNIAAGTDRRKADSDDGHGASTWDPDTPLYSMFNRFGSGTANLAFAPEMLDDRKPINIPSPRRIEFDKDRYAAIVNKLKAILVDLERSDTYLASLLNVLEATLSFVPSSTDASEVVDVSLFDHLKLTGALGACIWHYLQATGQSDFKSALFDKQDTFYNEKAFLLTTFDVSGIQDFIYTIHSSGAAKMLRARSFYLEMLTEHLIDELLARVGLSRANLNYSGGGHAYLLLPNTESARKSVEQFEREANDWLLENFATRLFIATGSVPLAANDLMRRPNESASQASNRALRYSGLYRELSEQLSAKKLARYSADQLRELNSRDHDGQKGDRECSVCHTVNRTVSADDEPKCSLCQALTAASSQIQSESRRFLLISDGATKGLPLPFGATLTFCSRADADKALQQPQTRRRYAKNKFFAGECLGTGLWVGDYVAQMEFGDYVKRASGIARLGVLRLDVDNLGQAFTHGFMEQGNGKFNTISRTAAFSRMLSLFFRQHINYVLARPKLRPITGDDPARPREATIIYSGGDDVFVVGAWDDVIEFGIELRERFHEFTQGKLTVSAGIGMFPDKYPISVMAREVGDLEDAAKSLPGKNGVALFDREFTFGWDELLSKVIEEKYRHIADYFSGNEERGMAFIYKLLELLAERDDRITKARWVYFLTRMRNPTGDTAPFQQFANRLHQWFQDPTDAKQLKTALHLYIYRTRKEESE
>NC_020559.1|WP_003912014.1|3120178_3120901_-|CRISPR-associated-endoribonuclease-Cas6
MATLGPHLHGVLMESIPADYVQTLHTVPVNPYSQYALARSTTSLEWKISTLTNEARQQIVGPINDAAFAGFRLRASGIATQVTSRSLEQNPLSQFARIFYARPETRKFRVEFLTPTAFKQSGEYVFWPDPRLVFQSLAQKYGAIVDGEEPDPGLIAEFGQSVRLSAFRVASAPFAVGAARVPGFTGSATFTVRGVDTFASYIAALLWFGEFSGCGIKASMGMGAIRVQPLAPREKCVPKP

Crispr_ID: NC_020559_14

• CRISPR_ID: NC_020559_14
• CRISPR_location: 3108130-3109998
• CRISPR_type: TypeIII
• Repeat_type: II-B,III-A
• Spacer_info: 25 spacers
• Cas_protein_info: cas2,cas1,csm4gr5,csm3gr7,csm2gr11,cas10,cas6

Consensus repeat of NC_020559_14

Consensus_repeat	Method
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CRISPRCasFinder
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CRT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	PILER-CR

spacers of NC_020559_14

>14.1|3108166|40|NC_020559|CRISPRCasFinder,CRT
TCGCGGCGAGCACGTCTCACCCAGCAGGCGGTGAGGTTGG
>14.2|3108242|39|NC_020559|CRISPRCasFinder,CRT,PILER-CR
ACGGACGAGCTGGACCGCATCAGCGATGCTGAGCTGAGG
>14.3|3108317|37|NC_020559|CRISPRCasFinder,CRT,PILER-CR
TTGTCTCAATCGTGCCGTCTGCGGTGACACGCTCCAA
>14.4|3108390|40|NC_020559|CRISPRCasFinder,CRT,PILER-CR
TCGACGATTGGGACATCGACATCGACGCGATCGTCGACGA
>14.5|3108466|41|NC_020559|CRISPRCasFinder,CRT,PILER-CR
GTGATCTTCTCTCCTGGCGAGGTCAAGGAAATCGATGTGGA
>14.6|3108543|36|NC_020559|CRISPRCasFinder,CRT,PILER-CR
CACCAGGATCAGCGCCAAGCCAGTTAGCGCAATCCA
>14.7|3108615|36|NC_020559|CRISPRCasFinder,CRT,PILER-CR
CTCCCGGACCATCTGCAGCTCGCCCGGGTCCATGCG
>14.8|3108687|37|NC_020559|CRISPRCasFinder,CRT,PILER-CR
CGGAGTCATCCGCGCGGGCCGGCGCGATTGTTGCCGG
>14.9|3108760|36|NC_020559|CRISPRCasFinder,CRT,PILER-CR
TGGCGATTTACGACGCTGACGGGAACTCGTGCGAAT
>14.10|3108832|25|NC_020559|CRISPRCasFinder,CRT
CGAAATTCACTGCGCGTTATTCAAG
>14.11|3108893|42|NC_020559|CRISPRCasFinder,CRT
CCGAGCCGACCATCCGCGATCACACCGAAAGGGTTGGCGCAA
>14.12|3108971|36|NC_020559|CRISPRCasFinder,CRT
ACGTGGGGAGAGGGAATGGCAATGATGGTCGACGAA
>14.13|3109043|40|NC_020559|CRISPRCasFinder,CRT
CTCGGACAGCATCTCCCCGGGCGGGCAGCAGATATCCCAT
>14.14|3109119|41|NC_020559|CRISPRCasFinder,CRT
CGACCCGTGGCCGCCAGGTTGCCGCCGCCGTTGCTCACCTG
>14.15|3109196|37|NC_020559|CRISPRCasFinder,CRT
CCGGAAGTCAACTAGAGCGGGTGTCGAACGCTGCCCG
>14.16|3109269|35|NC_020559|CRISPRCasFinder,CRT
ATGCGAATCCGCTGTCAGCACATGGGATTCCGAGT
>14.17|3109340|37|NC_020559|CRISPRCasFinder,CRT
CTAGGCGGCCCCGGCGAGGCTGGGGGCGGTTTCACGC
>14.18|3109413|38|NC_020559|CRISPRCasFinder,CRT
CAGCGCAGACGGCAGCCCCGAGTACTCGCTCTCCTCAG
>14.19|3109487|37|NC_020559|CRISPRCasFinder,CRT
AGGCTGAAATTGAAGCCGGAAATGACGACGCATTGGT
>14.20|3109560|35|NC_020559|CRISPRCasFinder,CRT
CTAAGCCCGCTAATCCCGCACAAGTGGTCAGAAAA
>14.21|3109631|39|NC_020559|CRISPRCasFinder,CRT
CTGATGATTGGTCGGCGTATGACGTGCTACTGAGGTGTT
>14.22|3109706|34|NC_020559|CRISPRCasFinder,CRT
TAGAAGGCGATCACTGGAAGCACGGCGCTTGCGA
>14.23|3109776|36|NC_020559|CRISPRCasFinder,CRT
TTGGTCAAAAGCTGTCGCCCAAGCATGAGGCAAAAA
>14.24|3109848|41|NC_020559|CRISPRCasFinder,CRT
ACGACTAGGGGAGCGTGATCCAGAGCCGGCGACCCTCTATG
>14.25|3109925|38|NC_020559|CRISPRCasFinder,CRT
GTGCAAGAATTCCGGGTTGCAGTGCAACACGGTTTTAA
>14.26|3108832|29|NC_020559|PILER-CR
TCCGCGAAATTCACTGCGCGTTATTCAAG
>14.27|3108897|42|NC_020559|PILER-CR
CCGAGCCGACCATCCGCGATCACACCGAAAGGGTTGGCGCAA
>14.28|3108975|36|NC_020559|PILER-CR
ACGTGGGGAGAGGGAATGGCAATGATGGTCGACGAA
>14.29|3109047|40|NC_020559|PILER-CR
CTCGGACAGCATCTCCCCGGGCGGGCAGCAGATATCCCAT
>14.30|3109123|41|NC_020559|PILER-CR
CGACCCGTGGCCGCCAGGTTGCCGCCGCCGTTGCTCACCTG
>14.31|3109200|37|NC_020559|PILER-CR
CCGGAAGTCAACTAGAGCGGGTGTCGAACGCTGCCCG
>14.32|3109273|35|NC_020559|PILER-CR
ATGCGAATCCGCTGTCAGCACATGGGATTCCGAGT
>14.33|3109344|37|NC_020559|PILER-CR
CTAGGCGGCCCCGGCGAGGCTGGGGGCGGTTTCACGC
>14.34|3109417|38|NC_020559|PILER-CR
CAGCGCAGACGGCAGCCCCGAGTACTCGCTCTCCTCAG
>14.35|3109491|37|NC_020559|PILER-CR
AGGCTGAAATTGAAGCCGGAAATGACGACGCATTGGT
>14.36|3109564|35|NC_020559|PILER-CR
CTAAGCCCGCTAATCCCGCACAAGTGGTCAGAAAA
>14.37|3109635|39|NC_020559|PILER-CR
CTGATGATTGGTCGGCGTATGACGTGCTACTGAGGTGTT
>14.38|3109710|34|NC_020559|PILER-CR
TAGAAGGCGATCACTGGAAGCACGGCGCTTGCGA
>14.39|3109780|36|NC_020559|PILER-CR
TTGGTCAAAAGCTGTCGCCCAAGCATGAGGCAAAAA
>14.40|3109852|41|NC_020559|PILER-CR
ACGACTAGGGGAGCGTGATCCAGAGCCGGCGACCCTCTATG
>14.41|3109929|38|NC_020559|PILER-CR
GTGCAAGAATTCCGGGTTGCAGTGCAACACGGTTTTAA

CRISPR arrays and Neighbor proteins around NC_020559_14

CRISPR arrays

The CRISPR arrays of NC_020559_14

>merge|NC_020559|14|3108130-3109998|CRISPRCasFinder,CRT,PILER-CR
CATGCCGGGGCGGTTCAGGGTTTTGGGTCTGACGACTCGCGGCGAGCACGTCTCACCCAGCAGGCGGTGAGGTTGGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACGGACGAGCTGGACCGCATCAGCGATGCTGAGCTGAGGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTTGTCTCAATCGTGCCGTCTGCGGTGACACGCTCCAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTCGACGATTGGGACATCGACATCGACGCGATCGTCGACGAGTTTCCGTCCTCTCTCGGGGTTTTGGGTCTGACGACGTGATCTTCTCTCCTGGCGAGGTCAAGGAAATCGATGTGGAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCACCAGGATCAGCGCCAAGCCAGTTAGCGCAATCCAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTCCCGGACCATCTGCAGCTCGCCCGGGTCCATGCGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCGGAGTCATCCGCGCGGGCCGGCGCGATTGTTGCCGGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTGGCGATTTACGACGCTGACGGGAACTCGTGCGAATGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGATCCGCGAAATTCACTGCGCGTTATTCAAGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCCGAGCCGACCATCCGCGATCACACCGAAAGGGTTGGCGCAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACGTGGGGAGAGGGAATGGCAATGATGGTCGACGAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTCGGACAGCATCTCCCCGGGCGGGCAGCAGATATCCCATGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCGACCCGTGGCCGCCAGGTTGCCGCCGCCGTTGCTCACCTGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCCGGAAGTCAACTAGAGCGGGTGTCGAACGCTGCCCGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACATGCGAATCCGCTGTCAGCACATGGGATTCCGAGTGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTAGGCGGCCCCGGCGAGGCTGGGGGCGGTTTCACGCGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCAGCGCAGACGGCAGCCCCGAGTACTCGCTCTCCTCAGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACAGGCTGAAATTGAAGCCGGAAATGACGACGCATTGGTGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTAAGCCCGCTAATCCCGCACAAGTGGTCAGAAAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTGATGATTGGTCGGCGTATGACGTGCTACTGAGGTGTTGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTAGAAGGCGATCACTGGAAGCACGGCGCTTGCGAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTTGGTCAAAAGCTGTCGCCCAAGCATGAGGCAAAAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACGACTAGGGGAGCGTGATCCAGAGCCGGCGACCCTCTATGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACGTGCAAGAATTCCGGGTTGCAGTGCAACACGGTTTTAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC

>NC_020559|14|9|3108130-3109998|CRISPRCasFinder
CATGCCGGGGCGGTTCAGGGTTTTGGGTCTGACGAC	TCGCGGCGAGCACGTCTCACCCAGCAGGCGGTGAGGTTGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACGGACGAGCTGGACCGCATCAGCGATGCTGAGCTGAGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TTGTCTCAATCGTGCCGTCTGCGGTGACACGCTCCAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TCGACGATTGGGACATCGACATCGACGCGATCGTCGACGA
GTTTCCGTCCTCTCTCGGGGTTTTGGGTCTGACGAC	GTGATCTTCTCTCCTGGCGAGGTCAAGGAAATCGATGTGGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CACCAGGATCAGCGCCAAGCCAGTTAGCGCAATCCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTCCCGGACCATCTGCAGCTCGCCCGGGTCCATGCG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CGGAGTCATCCGCGCGGGCCGGCGCGATTGTTGCCGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGGCGATTTACGACGCTGACGGGAACTCGTGCGAAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGATCCG	CGAAATTCACTGCGCGTTATTCAAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGAGCCGACCATCCGCGATCACACCGAAAGGGTTGGCGCAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACGTGGGGAGAGGGAATGGCAATGATGGTCGACGAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTCGGACAGCATCTCCCCGGGCGGGCAGCAGATATCCCAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CGACCCGTGGCCGCCAGGTTGCCGCCGCCGTTGCTCACCTG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGGAAGTCAACTAGAGCGGGTGTCGAACGCTGCCCG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ATGCGAATCCGCTGTCAGCACATGGGATTCCGAGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTAGGCGGCCCCGGCGAGGCTGGGGGCGGTTTCACGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CAGCGCAGACGGCAGCCCCGAGTACTCGCTCTCCTCAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	AGGCTGAAATTGAAGCCGGAAATGACGACGCATTGGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTAAGCCCGCTAATCCCGCACAAGTGGTCAGAAAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTGATGATTGGTCGGCGTATGACGTGCTACTGAGGTGTT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TAGAAGGCGATCACTGGAAGCACGGCGCTTGCGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TTGGTCAAAAGCTGTCGCCCAAGCATGAGGCAAAAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACGACTAGGGGAGCGTGATCCAGAGCCGGCGACCCTCTATG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	GTGCAAGAATTCCGGGTTGCAGTGCAACACGGTTTTAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC

>NC_020559|14|3|3108130-3109998|CRT
CATGCCGGGGCGGTTCAGGGTTTTGGGTCTGACGAC	TCGCGGCGAGCACGTCTCACCCAGCAGGCGGTGAGGTTGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACGGACGAGCTGGACCGCATCAGCGATGCTGAGCTGAGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TTGTCTCAATCGTGCCGTCTGCGGTGACACGCTCCAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TCGACGATTGGGACATCGACATCGACGCGATCGTCGACGA
GTTTCCGTCCTCTCTCGGGGTTTTGGGTCTGACGAC	GTGATCTTCTCTCCTGGCGAGGTCAAGGAAATCGATGTGGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CACCAGGATCAGCGCCAAGCCAGTTAGCGCAATCCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTCCCGGACCATCTGCAGCTCGCCCGGGTCCATGCG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CGGAGTCATCCGCGCGGGCCGGCGCGATTGTTGCCGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGGCGATTTACGACGCTGACGGGAACTCGTGCGAAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGATCCG	CGAAATTCACTGCGCGTTATTCAAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGAGCCGACCATCCGCGATCACACCGAAAGGGTTGGCGCAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACGTGGGGAGAGGGAATGGCAATGATGGTCGACGAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTCGGACAGCATCTCCCCGGGCGGGCAGCAGATATCCCAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CGACCCGTGGCCGCCAGGTTGCCGCCGCCGTTGCTCACCTG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CCGGAAGTCAACTAGAGCGGGTGTCGAACGCTGCCCG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ATGCGAATCCGCTGTCAGCACATGGGATTCCGAGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTAGGCGGCCCCGGCGAGGCTGGGGGCGGTTTCACGC
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CAGCGCAGACGGCAGCCCCGAGTACTCGCTCTCCTCAG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	AGGCTGAAATTGAAGCCGGAAATGACGACGCATTGGT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTAAGCCCGCTAATCCCGCACAAGTGGTCAGAAAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTGATGATTGGTCGGCGTATGACGTGCTACTGAGGTGTT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TAGAAGGCGATCACTGGAAGCACGGCGCTTGCGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TTGGTCAAAAGCTGTCGCCCAAGCATGAGGCAAAAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACGACTAGGGGAGCGTGATCCAGAGCCGGCGACCCTCTATG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	GTGCAAGAATTCCGGGTTGCAGTGCAACACGGTTTTAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC

>NC_020559|14|6|3108206-3109998|PILER-CR
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	ACGGACGAGCTGGACCGCATCAGCGATGCTGAGCTGAGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TTGTCTCAATCGTGCCGTCTGCGGTGACACGCTCCAA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TCGACGATTGGGACATCGACATCGACGCGATCGTCGACGA
GTTTCCGTCCTCTCTCGGGGTTTTGGGTCTGACGAC	GTGATCTTCTCTCCTGGCGAGGTCAAGGAAATCGATGTGGA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CACCAGGATCAGCGCCAAGCCAGTTAGCGCAATCCA
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CTCCCGGACCATCTGCAGCTCGCCCGGGTCCATGCG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	CGGAGTCATCCGCGCGGGCCGGCGCGATTGTTGCCGG
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	TGGCGATTTACGACGCTGACGGGAACTCGTGCGAAT
GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGATCCG	CGAAATTCACTGCGCGTTATTCAAGGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCCGA	GCCGACCATCCGCGATCACACCGAAAGGGTTGGCGCAAGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACGT	GGGGAGAGGGAATGGCAATGATGGTCGACGAAGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTCG	GACAGCATCTCCCCGGGCGGGCAGCAGATATCCCATGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCGAC	CCGTGGCCGCCAGGTTGCCGCCGCCGTTGCTCACCTGGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCCGG	AAGTCAACTAGAGCGGGTGTCGAACGCTGCCCGGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACATGC	GAATCCGCTGTCAGCACATGGGATTCCGAGTGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTAG	GCGGCCCCGGCGAGGCTGGGGGCGGTTTCACGCGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCAGC	GCAGACGGCAGCCCCGAGTACTCGCTCTCCTCAGGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACAGGC	TGAAATTGAAGCCGGAAATGACGACGCATTGGTGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTAA	GCCCGCTAATCCCGCACAAGTGGTCAGAAAAGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTGA	TGATTGGTCGGCGTATGACGTGCTACTGAGGTGTTGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTAGA	AGGCGATCACTGGAAGCACGGCGCTTGCGAGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTTGG	TCAAAAGCTGTCGCCCAAGCATGAGGCAAAAAGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACGA	CTAGGGGAGCGTGATCCAGAGCCGGCGACCCTCTATGGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGACGTGC	AAGAATTCCGGGTTGCAGTGCAACACGGTTTTAAGTTT
CCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_003414288.1|3115763_3116672_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl|CDD|224483
NC_020559.1|WP_003414190.1|3102100_3102412_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003917684.1|3099157_3099412_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003414276.1|3110046_3110388_-|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|224262
NC_020559.1|WP_003899491.1|3104916_3105729_+|ExeA-family-protein	unknown	unknown	gnl|CDD|225806
NC_020559.1|WP_003913758.1|3121300_3121846_-|DUF1802-family-protein	unknown	unknown	gnl|CDD|226743
NC_020559.1|WP_003899489.1|3101738_3101996_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003900580.1|3117743_3120182_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	COG1353_cas10_CAS-III	gnl|CDD|187811
NC_020559.1|WP_003414198.1|3103510_3104920_+|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NC_020559.1|WP_003414296.1|3117372_3117747_-|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl|CDD|273844
NC_020559.1|WP_003899488.1|3100350_3101505_+|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NC_020559.1|WP_087902221.1|3111661_3112923_-|IS3-like-element-IS987-family-transposase	unknown	unknown	gnl|CDD|222853
NC_020559.1|WP_003414292.1|3116652_3117363_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187815
NC_020559.1|WP_003414184.1|3099960_3100152_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003414195.1|3102831_3103440_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_009938577.1|3099559_3099964_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003414279.1|3110388_3111405_-|CRISPR-associated-endonuclease-Cas1	cas1	COG1518_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|272998
NC_020559.1|WP_087902221.1|3113615_3114877_-|IS3-like-element-IS987-family-transposase	unknown	unknown	gnl|CDD|222853
NC_020559.1|WP_087902221.1|3106833_3108095_-|IS3-like-element-IS987-family-transposase	unknown	unknown	gnl|CDD|222853
NC_020559.1|WP_003912014.1|3120178_3120901_-|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl|CDD|227838

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_020559.1|WP_003414288.1|3115763_3116672_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	1.3e-98	324.8	0.0
NC_020559.1|WP_003414292.1|3116652_3117363_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	6.2e-81	265.9	0.0
NC_020559.1|WP_003414276.1|3110046_3110388_-|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	5.6e-26	85.5	0.1
NC_020559.1|WP_003414279.1|3110388_3111405_-|CRISPR-associated-endonuclease-Cas1	cas1	COG1518_cas1_CAS-I:CAS-II:CAS-III	1e-108	357.9	0.0
NC_020559.1|WP_003912014.1|3120178_3120901_-|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	9.8e-88	288.8	0.1
NC_020559.1|WP_003900580.1|3117743_3120182_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	COG1353_cas10_CAS-III	1.9e-238	788.5	0.0
NC_020559.1|WP_003414296.1|3117372_3117747_-|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	2.1e-23	77.8	0.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_003414288.1|3115763_3116672_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl|CDD|224483	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.37381e-109
NC_020559.1|WP_003913758.1|3121300_3121846_-|DUF1802-family-protein	gnl|CDD|226743	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown].	1.13775e-85
NC_020559.1|WP_003414198.1|3103510_3104920_+|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	7.41102e-28
NC_020559.1|WP_003414276.1|3110046_3110388_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	3.66595e-25
NC_020559.1|WP_003899491.1|3104916_3105729_+|ExeA-family-protein	gnl|CDD|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	3.94464e-110
NC_020559.1|WP_003900580.1|3117743_3120182_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl|CDD|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
NC_020559.1|WP_003899488.1|3100350_3101505_+|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.94329e-16
NC_020559.1|WP_003414296.1|3117372_3117747_-|type-III-A-CRISPR-associated-protein-Csm2	gnl|CDD|273844	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2. These proteins are found adjacent to a characteristic short, palidromic repeat cluster termed CRISPR, a probable mobile DNA element. This model represents the C-terminal domain of a minor family of CRISPR-associated protein from the Mtube subtype of CRISPR/Cas locus. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2.	4.56134e-21
NC_020559.1|WP_087902221.1|3111661_3112923_-|IS3-like-element-IS987-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.28492e-102
NC_020559.1|WP_003414292.1|3116652_3117363_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl|CDD|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	4.36536e-99
NC_020559.1|WP_087902221.1|3113615_3114877_-|IS3-like-element-IS987-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.28492e-102
NC_020559.1|WP_003414279.1|3110388_3111405_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|272998	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1. This model identifies CRISPR-associated protein Cas1, the most universal CRISPR system protein. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Cas1 is a metal-dependent DNA-specific endonuclease.	2.72742e-113
NC_020559.1|WP_087902221.1|3106833_3108095_-|IS3-like-element-IS987-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.28492e-102
NC_020559.1|WP_003912014.1|3120178_3120901_-|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.14295e-72

Protein sequences

>NC_020559.1|WP_087902221.1|3106833_3108095_-|IS3-like-element-IS987-family-transposase
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_020559.1|WP_003899491.1|3104916_3105729_+|ExeA-family-protein
MMHKLISYYGFSRMPFGRDLAPGMLHRHSAHNEAVARIGWCIADRRIGVITGEVGAGKTVAVRAALASLDRSRHTIIYLPDPTVGVQGIHHRIVASLGGQPLTHHATLAPQAADALAAEQAERGRTPVVVVEEAHLLGYDQLEALRLLTNHDLDSSSPFACLLIGQPTLRRRMKLGVLAALDQRIGLRYAMPPMTDTNTGSYLRHHLKLAGRDDALFSDDAIGLIHQTSRGYPRAVNNLALQALVAAFAADKAIVDESTTRTAIAEVTAD
>NC_020559.1|WP_003414198.1|3103510_3104920_+|DDE-type-integrase/transposase/recombinase
MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQRGKMVRELASREHTDPFGRRVRISRQTIDRWIRGWRAGGFDALVPNPRQCTPRTPAEVLELAVALRRENPQRTAAAIRRILRTQLGWAPDERTLQRNFHRLGLTGATTGSAPAVFGRFEAEHPNALWTGDVLHGIRIDLRKTYLFAFLDDHSRLVPGYRWGHAEDTVRLAAALRPALASRGVPNAVYVDNGSPYVDAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFLVEITGEPDVVGRHYVADLAELNRLFTAWVETVYHRSVHSETGQTPLARWSAGGPIPLPAPETLTEAFLWEEHRRVTKTATVSLHGNRYEIDPALVGRKVELVFDPFDLTRIEVRLAGAPMGRAIPYHIGRHSHPKAKPETPTAPPKPSGIDYAQLIETAHAAELARGVNYTALTGAADQIPGQLDLLTGQEAQPK
>NC_020559.1|WP_003414195.1|3102831_3103440_+|hypothetical-protein
MVTVEADVDQVERRLAAGELSCPSCGGVLAGWGRARSRQLRGPAGPVELCPRRSRCTGCGVTHVLLPVSALLRRADTAAVIVSALAAKATSRVGFRRIATDVARPAETVRGWLRRFAERVEAVRSVFTVWLCAVDADPVMPDAGGGGFVDAVVAIGALAAAIGRRFSLPTVSLAETAVAVSGGRLLAPGWPGEWVQHESTLP
>NC_020559.1|WP_003414190.1|3102100_3102412_+|hypothetical-protein
MTYAARDDTTLPKLLAQMRWVVLVDKRQLAVLLLENEGPVASATDTLDTRGDSDYENQPVDAVERLCRRLADQAVRQWGFMQGLKQKLGPGVDVRMKLVEWNR
>NC_020559.1|WP_003899489.1|3101738_3101996_+|hypothetical-protein
MSNVLDAISTEHRPVIEQELENRNPALFDELRRTEKPTNEQSDAVIDVLSDALMKTFGPDWVPNDYGLKIERAIDAYLETWPIYR
>NC_020559.1|WP_003899488.1|3100350_3101505_+|DDE-type-integrase/transposase/recombinase
MVSTTGMGRSTARRMLTGPGLPEPAEQVDGRRLRARGFSDDARALLEHVWALMGMPCGKYLVVMLELWLPLVAAAGDLDKPFATEAAVAELKAMSAATVDRYLKPARERMRIKGISTTKPSPLLRNSITIHTCSDEAPKVPGVIEADTVAHCGPSLIGEFARTLTMTDLVTGWTENASIRNNAAKWILEGIKECQQRFPFPMTVFDSDCGGEFINHDVAGWLQARDIAQTRSRPYQKNDQAHVESKNNHVVRKHAFYWRYDTGEELELLNRLWPLVSLRCNFFTPTKKPVGYTSTVNGRRKRIYDKPATPWQRLQASGVLDAQQLSTVAARIEGFNPADLTRQINAIQMQLLDLAKTKTEALATARHIDLQSLQPSINRLAKAK
>NC_020559.1|WP_003414184.1|3099960_3100152_+|hypothetical-protein
MKTNPRYGPAFYSVMTVLFLALFVLNVCTHGSTLGLISTGGLAVLMGYIGYRGWSGKRHINRQ
>NC_020559.1|WP_009938577.1|3099559_3099964_+|hypothetical-protein
MGRGNGKILDPVVATTGMGRSTARQMLTGPRLPGPAEQVDGRSLRPRGFSDEARALLEHVWALMGMPCGKYLVVMHDLWLPLLTAAGDLDKPLVTEASVAELKATALPGANRMPHWAAGTLPDGFPARAVRTRT
>NC_020559.1|WP_003917684.1|3099157_3099412_-|hypothetical-protein
MTVELGGAVVDGVDDQGAGAVVPGTGHGSDEGIEEKIATETGALLLPVERQASEDEHWDRVGSGWPRPGRDGTRIRSMLPMASA
>NC_020559.1|WP_003414276.1|3110046_3110388_-|CRISPR-associated-endonuclease-Cas2
MPTRSREEYFNLPLKVDESSGTIGKMFVLVIYDISDNRRRASLAKILAGFGYRVQESAFEAMLTKGQLAKLVARIDRFAIDCDNIRIYKIRGVAAVTFYGRGRLVSAEEFVFF
>NC_020559.1|WP_003414279.1|3110388_3111405_-|CRISPR-associated-endonuclease-Cas1
MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHRYTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA
>NC_020559.1|WP_087902221.1|3111661_3112923_-|IS3-like-element-IS987-family-transposase
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_020559.1|WP_087902221.1|3113615_3114877_-|IS3-like-element-IS987-family-transposase
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_020559.1|WP_003414288.1|3115763_3116672_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRLTDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLKGISALGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPESAA
>NC_020559.1|WP_003414292.1|3116652_3117363_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MTTSYAKIEITGTLTVLTGLQIGAGDGFSAIGAVDKPVVRDPLSRLPMIPGTSLKGKVRTLLSRQYGADTETFYRKPNEDHAHIRRLFGDTEEYMTGRLVFRDTKLTNKDDLEARGAKTLTEVKFENAINRVTAKANLRQMERVIPGSEFAFSLVYEVSFGTPGEEQKASLPSSDEIIEDFNAIARGLKLLELDYLGGSGTRGYGQVKFSNLKARAAVGALDGSLLEKLNHELAAV
>NC_020559.1|WP_003414296.1|3117372_3117747_-|type-III-A-CRISPR-associated-protein-Csm2
MSVIQDDYVKQAEVIRGLPKKKNGFELTTTQLRVLLSLTAQLFDEAQQSANPTLPRQLKEKVQYLRVRFVYQSGREDAVKTFVRNAKLLEALEGIGDSRDGLLRFCRYMEALAAYKKYLDPKDK
>NC_020559.1|WP_003900580.1|3117743_3120182_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MNPQLIEAIIGCLLHDIGKPVQRAALGYPGRHSAIGRAFMKKVWLRDSRNPSQFTDEVDEADIGVSDRRILDAISYHHSSALRTAAENGRLAADAPAYIAYIADNIAAGTDRRKADSDDGHGASTWDPDTPLYSMFNRFGSGTANLAFAPEMLDDRKPINIPSPRRIEFDKDRYAAIVNKLKAILVDLERSDTYLASLLNVLEATLSFVPSSTDASEVVDVSLFDHLKLTGALGACIWHYLQATGQSDFKSALFDKQDTFYNEKAFLLTTFDVSGIQDFIYTIHSSGAAKMLRARSFYLEMLTEHLIDELLARVGLSRANLNYSGGGHAYLLLPNTESARKSVEQFEREANDWLLENFATRLFIATGSVPLAANDLMRRPNESASQASNRALRYSGLYRELSEQLSAKKLARYSADQLRELNSRDHDGQKGDRECSVCHTVNRTVSADDEPKCSLCQALTAASSQIQSESRRFLLISDGATKGLPLPFGATLTFCSRADADKALQQPQTRRRYAKNKFFAGECLGTGLWVGDYVAQMEFGDYVKRASGIARLGVLRLDVDNLGQAFTHGFMEQGNGKFNTISRTAAFSRMLSLFFRQHINYVLARPKLRPITGDDPARPREATIIYSGGDDVFVVGAWDDVIEFGIELRERFHEFTQGKLTVSAGIGMFPDKYPISVMAREVGDLEDAAKSLPGKNGVALFDREFTFGWDELLSKVIEEKYRHIADYFSGNEERGMAFIYKLLELLAERDDRITKARWVYFLTRMRNPTGDTAPFQQFANRLHQWFQDPTDAKQLKTALHLYIYRTRKEESE
>NC_020559.1|WP_003912014.1|3120178_3120901_-|CRISPR-associated-endoribonuclease-Cas6
MATLGPHLHGVLMESIPADYVQTLHTVPVNPYSQYALARSTTSLEWKISTLTNEARQQIVGPINDAAFAGFRLRASGIATQVTSRSLEQNPLSQFARIFYARPETRKFRVEFLTPTAFKQSGEYVFWPDPRLVFQSLAQKYGAIVDGEEPDPGLIAEFGQSVRLSAFRVASAPFAVGAARVPGFTGSATFTVRGVDTFASYIAALLWFGEFSGCGIKASMGMGAIRVQPLAPREKCVPKP
>NC_020559.1|WP_003913758.1|3121300_3121846_-|DUF1802-family-protein
MTPALKEWSAAVHALLDGRQTVLLRKGGIGEKRFEVAAHEFLLFPTVAHSHAERVRPEHRDLLGPAAADSTDECVLLRAAAKVVAALPVNRPEGLDAIEDLHIWTAESVRADRLDFRPKHKLAVLVVSAIPLAEPVRLARRPEYGGCTSWVQLPVTPTLAAPVHDEAALAEVAARVREAVG

Crispr_ID: NC_020559_15

• CRISPR_ID: NC_020559_15
• CRISPR_location: 3723832-3724373
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 7 spacers

Consensus repeat of NC_020559_15

Consensus_repeat	Method
CCGCCGTTNCCNCCGTTGCCGCC	CRT

spacers of NC_020559_15

>15.1|3723855|52|NC_020559|CRT
GTTGCCGGCCTTAGCGAACGTGGCGAAGGCGTCACCACCCTTGCCGCCGATG
>15.2|3723930|58|NC_020559|CRT
CTGTCCGCCATTCGCGCCATTGGCGGACGCGGAGAAGTCTTGGCCGTTGGCTCCGGCG
>15.3|3724011|43|NC_020559|CRT
GTCCCCGCCCGTGCCGGCCGCCGATCCGCCGTTGCCGCCGATG
>15.4|3724077|79|NC_020559|CRT
GTTGAGGGCAAGGCCGGTGCCGGCGACGCCATTTCCGCCGGCACCACCCGCACCGCCGTTACCGACCGACCCGCCATGG
>15.5|3724179|34|NC_020559|CRT
GTTTTCTCCCGCGACGGTGGGGGTGGCGCCGGCA
>15.6|3724236|61|NC_020559|CRT
GCTGGTGGGCGCGGTGCCGTTCGCCCCGGCCGAACCGTTCAGGGCCGGGTTCGCGCTAACA
>15.7|3724320|31|NC_020559|CRT
AACGCCCACTTCACCGCCGTTGCCGCCGTCA

CRISPR arrays and Neighbor proteins around NC_020559_15

CRISPR arrays

The CRISPR arrays of NC_020559_15

>merge|NC_020559|15|3723832-3724373|CRT
CCGCCGTTGCCGCCGGCACCGCCGTTGCCGGCCTTAGCGAACGTGGCGAAGGCGTCACCACCCTTGCCGCCGATGCCGCCGTTGCCGCCGTTGCCGCCCTGTCCGCCATTCGCGCCATTGGCGGACGCGGAGAAGTCTTGGCCGTTGGCTCCGGCGCCCCCGTTGCCGCCCTTGCCGCCGTCCCCGCCCGTGCCGGCCGCCGATCCGCCGTTGCCGCCGATGCCGCCGTTGCCGCCGTTGCCGCCGTTGAGGGCAAGGCCGGTGCCGGCGACGCCATTTCCGCCGGCACCACCCGCACCGCCGTTACCGACCGACCCGCCATGGCCGCCGTTACCACCGGCGCCGCCGTTTTCTCCCGCGACGGTGGGGGTGGCGCCGGCACCTCCGTTGCCACCGTTGCCGCCGCTGGTGGGCGCGGTGCCGTTCGCCCCGGCCGAACCGTTCAGGGCCGGGTTCGCGCTAACACCGCCGGCCCCACCCTTGCCGCCAACGCCCACTTCACCGCCGTTGCCGCCGTCACCGCCGGCACCCTGGTTGACGGC

>NC_020559|15|4|3723832-3724373|CRT
CCGCCGTTGCCGCCGGCACCGCC	GTTGCCGGCCTTAGCGAACGTGGCGAAGGCGTCACCACCCTTGCCGCCGATG
CCGCCGTTGCCGCCGTTGCCGCC	CTGTCCGCCATTCGCGCCATTGGCGGACGCGGAGAAGTCTTGGCCGTTGGCTCCGGCG
CCCCCGTTGCCGCCCTTGCCGCC	GTCCCCGCCCGTGCCGGCCGCCGATCCGCCGTTGCCGCCGATG
CCGCCGTTGCCGCCGTTGCCGCC	GTTGAGGGCAAGGCCGGTGCCGGCGACGCCATTTCCGCCGGCACCACCCGCACCGCCGTTACCGACCGACCCGCCATGG
CCGCCGTTACCACCGGCGCCGCC	GTTTTCTCCCGCGACGGTGGGGGTGGCGCCGGCA
CCTCCGTTGCCACCGTTGCCGCC	GCTGGTGGGCGCGGTGCCGTTCGCCCCGGCCGAACCGTTCAGGGCCGGGTTCGCGCTAACA
CCGCCGGCCCCACCCTTGCCGCC	AACGCCCACTTCACCGCCGTTGCCGCCGTCA
CCGCCGGCACCCTGGTTGACGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_003417738.1|3750506_3751301_-|BBE-domain-containing-protein	unknown	unknown	gnl|CDD|369658
NC_020559.1|WP_009938644.1|3720160_3721177_-|hypothetical-protein	unknown	unknown	gnl|CDD|312941
NC_020559.1|WP_015345172.1|3714268_3720112_-|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_020559.1|WP_157132559.1|3751651_3751870_-|hypothetical-protein	unknown	unknown	gnl|CDD|366708
NC_020559.1|WP_003417461.1|3713528_3714260_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NC_020559.1|WP_021036406.1|3721135_3721417_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003417619.1|3726370_3726628_-|DUF3017-domain-containing-protein	unknown	unknown	gnl|CDD|378602
NC_020559.1|WP_003417741.1|3751896_3752157_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003417440.1|3707525_3708536_-|tryptophan--tRNA-ligase	unknown	unknown	gnl|CDD|234866
NC_020559.1|WP_003417452.1|3709519_3710749_-|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl|CDD|236226
NC_020559.1|WP_003417745.1|3752271_3752661_+|DUF732-domain-containing-protein	unknown	unknown	gnl|CDD|368380
NC_020559.1|WP_003905041.1|3708808_3709453_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|184875
NC_020559.1|WP_003417435.1|3706635_3707505_-|inner-membrane-protein-YhjD	unknown	unknown	gnl|CDD|188082
NC_020559.1|WP_015345175.1|3726883_3736357_-|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_020559.1|WP_003417739.1|3751382_3751754_-|FAD-binding-oxidoreductase	unknown	unknown	gnl|CDD|223354
NC_020559.1|WP_003900028.1|3711031_3712381_+|bifunctional-o-acetylhomoserine/o-acetylserine-sulfhydrylase	unknown	unknown	gnl|CDD|236105
NC_020559.1|WP_003900675.1|3737465_3738206_-|transposase	unknown	unknown	gnl|CDD|376574
NC_020559.1|WP_009938650.1|3738500_3738788_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_049961743.1|3736982_3737429_+|transposase	unknown	unknown	gnl|CDD|376564
NC_020559.1|WP_003417458.1|3712392_3713532_+|homoserine-O-acetyltransferase	unknown	unknown	gnl|CDD|234678

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_003417738.1|3750506_3751301_-|BBE-domain-containing-protein	gnl|CDD|369658	pfam08031, BBE, Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine.	2.38492e-05
NC_020559.1|WP_009938644.1|3720160_3721177_-|hypothetical-protein	gnl|CDD|312941	pfam09606, Med15, ARC105 or Med15 subunit of Mediator complex non-fungal. The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.	0.000226013
NC_020559.1|WP_015345172.1|3714268_3720112_-|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	7.24138e-84
NC_020559.1|WP_003417452.1|3709519_3710749_-|NADP-dependent-isocitrate-dehydrogenase	gnl|CDD|236226	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase.	0
NC_020559.1|WP_003417461.1|3713528_3714260_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	1.03104e-26
NC_020559.1|WP_003417619.1|3726370_3726628_-|DUF3017-domain-containing-protein	gnl|CDD|378602	pfam11222, DUF3017, Protein of unknown function (DUF3017). This bacterial family of proteins with unknown function appear to be restricted to Actinobacteria.	3.92596e-11
NC_020559.1|WP_003417745.1|3752271_3752661_+|DUF732-domain-containing-protein	gnl|CDD|368380	pfam05305, DUF732, Protein of unknown function (DUF732). This family consists of several uncharacterized Mycobacterium tuberculosis and leprae proteins of unknown function.	4.49035e-23
NC_020559.1|WP_003417440.1|3707525_3708536_-|tryptophan--tRNA-ligase	gnl|CDD|234866	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed.	0
NC_020559.1|WP_015345175.1|3726883_3736357_-|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	8.70836e-79
NC_020559.1|WP_003905041.1|3708808_3709453_+|alpha/beta-fold-hydrolase	gnl|CDD|184875	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional.	1.56028e-15
NC_020559.1|WP_003417435.1|3706635_3707505_-|inner-membrane-protein-YhjD	gnl|CDD|188082	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD. This family, including YhjD in E. coli, is a conserved inner membrane protein homologous YihY, which in turn was incorrectly assigned to be ribonuclease BN. This, any suggestion this family is similar to ribonucleases should be removed. [Transcription, Degradation of RNA].	3.67774e-123
NC_020559.1|WP_003417739.1|3751382_3751754_-|FAD-binding-oxidoreductase	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	7.3689e-14
NC_020559.1|WP_003900028.1|3711031_3712381_+|bifunctional-o-acetylhomoserine/o-acetylserine-sulfhydrylase	gnl|CDD|236105	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated.	0
NC_020559.1|WP_003900675.1|3737465_3738206_-|transposase	gnl|CDD|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	1.82865e-20
NC_020559.1|WP_157132559.1|3751651_3751870_-|hypothetical-protein	gnl|CDD|366708	pfam01565, FAD_binding_4, FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.	3.12703e-05
NC_020559.1|WP_049961743.1|3736982_3737429_+|transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.45693e-11
NC_020559.1|WP_003417458.1|3712392_3713532_+|homoserine-O-acetyltransferase	gnl|CDD|234678	PRK00175, metX, homoserine O-acetyltransferase; Provisional.	0

Protein sequences

>NC_020559.1|WP_021036406.1|3721135_3721417_+|hypothetical-protein
MVTVAPVAALAAKHDAGAAGAAVAAVAAGAAANAAAAAPGATEPTLATCAAGAARVAAAAGAAVAAVTGVATASVAVAGTAVGASAALAAIAA
>NC_020559.1|WP_009938644.1|3720160_3721177_-|hypothetical-protein
MLGGKGGDGGNGDHGGPATNPGSGSRGGAGGSGGNGGAGGNATGSGGKGGAGGNGGDGSFGATSGPASIGVTGAPGGNGGKGGAGGSNPNGSGGDGGKGGNGGAGGNGGSIGANSGIVGGSGGAGGAGGAGGNGSLSSGEGGKGGDGGHGGDGVGGNSSVTQGGSGGGGGAGGAGGSGFFGGKGGFGGDGGQGGPNGGGTVGTVAGGGGNGGVGGRGGDGVFAGAGGQGGLGGQGGNGGGSTGGNGGLGGAGGGGGNAPDGGFGGNGGKGGQGGIGGGTQSATGLGGDGGDGGDGGNGGNSGAKAGGAGGKGQAGQPNSGTEPGFGGDGGLGGAGATP
>NC_020559.1|WP_015345172.1|3714268_3720112_-|PPE-family-protein
MSFVVMPPEINSLLIYTGAGPGPLLAAAAAWDELAAELGSAAAAFGSVTSGLVGGIWQGPSSVAMAAAAAPYAGWLSAAAASAESAAGQARAVVGVFEAALAATVDPFVIAANRSRLVSLALSNLFGQNTPAIAAAEFDYELMWAQDVAAMLGYHTGASAAAEALAPFGSPLASLAAAAEPAKSLAVNLGLANVGLFNAGSGNVGSYNVGAGNVGSYNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIASTGLFNAGGFNTGVVNAGSYNTGSFNAGEANTGGFNPGSVNTGWLNTGDINTGVANSGDVNTGAFISGNYSNGVLWRGDYQGLLGFSSGANVLPVIPLSLDINGGVGAITIEPIHILPDIPININETLYLGPLVVPPINVPAISLGVGIPNISIGPIKINPITLWPAQNFNQTITLAWPVSSITIPQIQQVALSPSPIPTTLIGPIHINTGFSIPVTFSYSTPALTLFPVGLSIPTGGPLTLTLGVTAGTEAFTIPGFSIPEQPLPLAINVIGHINALSTPAITIDNIPLNLHAIGGVGPVDIVGGNVPASPGFGNSTTAPSSGFFNTGAGGVSGFGNVGAHTSGWFNQSTQAMQVLPGTVSGYFNSGTLMSGIGNVGTQLSGMLSGGALGGNNFGLGNIGFDNVGFGNAGSSNFGLANMGIGNIGLANTGNGNIGIGLSGDNLTGFGGFNSGSENVGLFNSGTGNVGFFNSGTGNLGVFNSGSHNTGFFLTGNNINVLAPFTPGTLFTISEIPIDLQVIGGIGPIHVQPIDIPAFDIQITGGFIGIREFTLPEITIPAIPIHVTGTVGLEGFHVNPAFVLFGQTAMAEITADPVVLPDPFITIDHYGPPLGPPGAKFPSGSFYLSISDLQINGPIIGSYGGPGTIPGPFGATFNLSTSSLALFPAGLTVPDQTPVTVNLTGGLDSITLFPGGLAFPENPVVSLTNFSVGTGGFTVFPQGFTVDRIPVDLHTTLSIGPFPFRWDYIPPTPANGPIPAVPGGFGLTSGLFPFHFTLNGGIGPISIPTTTVVDALNPLLTVTGNLEVGPFTVPDIPIPAINFGLDGNVNVSFNAPATTLLSGLGITGSIDISGIQITNIQTQPAQLFMSVGQTLFLFDFRDGIELNPIVIPGSSIPITMAGLSIPLPTVSESIPLNFSFGSPASTVKSMILHEILPIDVSINLEDAVFIPATVLPAIPLNVDVTIPVGPINIPIITEPGSGNSTTTTSDPFSGLAVPGLGVGLLGLFDGSIANNLISGFNSAVGIVGPNVGLSNLGGGNVGLGNVGDFNLGAGNVGGFNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIASTGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDTNTGVANSGDVNTGAFISGNYSNGAFWRGDYQGLLGFSYTSTIIPEFTVANIHASGGAGPIIVPSIQFPAIPLDLSATGHIGGFTIPPVSISPITVRIDPVFDLGPITVQDITIPALGLDPATGVTVGPIFSSGSIIDPFSLTLLGFINVNVPAIQTAPSEILPFTVLLSSLGVTHLTPEITIPGFHIPVDPIHVELPLSVTIGPFVSPEITIPQLPLGLALSGATPAFAFPLEITIDRIPVVLDVNALLGPINAGLVIPPVPGFGNTTAVPSSGFFNIGGGGGLSGFHNLGAGMSGVLNAISDPLLGSASGFANFGTQLSGILNRGADISGVYNTGALGLITSALVSGFGNVGQQLAGLIYTGTGP
>NC_020559.1|WP_003417461.1|3713528_3714260_+|class-I-SAM-dependent-methyltransferase
MTCSRRDMSLSFGSAVGAYERGRPSYPPEAIDWLLPAAARRVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDVLRAALPQTVALLGTAEEIPLDDNSVDAVLVAQAWHWVDPARAIPEVARVLRPGGRLGLVWNTRDERLGWVRELGEIIGRDGDPVRDRVTLPEPFTTVQRHQVEWTNYLTPQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATHPALANSNGLALPYVTVCVRATLA
>NC_020559.1|WP_003417458.1|3712392_3713532_+|homoserine-O-acetyltransferase
MTISDVPTQTLPAEGEIGLIDVGSLQLESGAVIDDVCIAVQRWGKLSPARDNVVVVLHALTGDSHITGPAGPGHPTPGWWDGVAGPGAPIDTTRWCAVATNVLGGCRGSTGPSSLARDGKPWGSRFPLISIRDQVQADVAALAALGITEVAAVVGGSMGGARALEWVVGYPDRVRAGLLLAVGARATADQIGTQTTQIAAIKADPDWQSGDYHETGRAPDAGLRLARRFAHLTYRGEIELDTRFANHNQGNEDPTAGGRYAVQSYLEHQGDKLLSRFDAGSYVILTEALNSHDVGRGRGGVSAALRACPVPVVVGGITSDRLYPLRLQQELADLLPGCAGLRVVESVYGHDGFLVETEAVGELIRQTLGLADREGACRR
>NC_020559.1|WP_003900028.1|3711031_3712381_+|bifunctional-o-acetylhomoserine/o-acetylserine-sulfhydrylase
MSADSNSTDADPTAHWSFETKQIHAGQHPDPTTNARALPIYATTSYTFDDTAHAAALFGLEIPGNIYTRIGNPTTDVVEQRIAALEGGVAALFLSSGQAAETFAILNLAGAGDHIVSSPRLYGGTYNLFHYSLAKLGIEVSFVDDPDDLDTWQAAVRPNTKAFFAETISNPQIDLLDTPAVSEVAHRNGVPLIVDNTIATPYLIQPLAQGADIVVHSATKYLGGHGAAIAGVIVDGGNFDWTQGRFPGFTTPDPSYHGVVFAELGPPAFALKARVQLLRDYGSAASPFNAFLVAQGLETLSLRIERHVANAQRVAEFLAARDDVLSVNYAGLPSSPWHERAKRLAPKGTGAVLSFELAGGIEAGKAFVNALKLHSHVANIGDVRSLVIHPASTTHAQLSPAEQLATGVSPGLVRLAVGIEGIDDILADLELGFAAARRFSADPQSVAAF
>NC_020559.1|WP_003417452.1|3709519_3710749_-|NADP-dependent-isocitrate-dehydrogenase
MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN
>NC_020559.1|WP_003905041.1|3708808_3709453_+|alpha/beta-fold-hydrolase
MSSAVLADHVERQLDELGWETSHIVGNSLGGWVAFELERRGRARSVTGIAPAGGWTRWSPVKFEVIAKFIAGAPILAVAHILGQRALRLPFSRLLATLPISATPDGVSERELSGIIDDAAHCPAYFQLLVKALVLPGLQELEHTAVPSHVVLCEQDRVVPPSRFSRHFTDSLPAGHRLTVLDGVGHVPMFEAPGRITELITSFIEECCPHVRAS
>NC_020559.1|WP_003417440.1|3707525_3708536_-|tryptophan--tRNA-ligase
MSTPTGSRRIFSGVQPTSDSLHLGNALGAVAQWVGLQDDHDAFFCVVDLHAITIPQDPEALRRRTLITAAQYLALGIDPGRATIFVQSQVPAHTQLAWVLGCFTGFGQASRMTQFKDKSARQGSEATTVGLFTYPVLQAADVLAYDTELVPVGEDQRQHLELARDVAQRFNSRFPGTLVVPDVLIPKMTAKIYDLQDPTSKMSKSAGTDAGLINLLDDPALSAKKIRSAVTDSERDIRYDPDVKPGVSNLLNIQSAVTGTDIDVLVDGYAGHGYGDLKKDTAEAVVEFVNPIQARVDELTADPAELEAVLAAGAQRAHDVASKTVQRVYDRLGFLL
>NC_020559.1|WP_003417435.1|3706635_3707505_-|inner-membrane-protein-YhjD
MGELAEPGVLDRLRARFGWLDHVVRAFTRFNDRNGSLFAAGLTYYTIFAIFPLLMVGFGVGGFALSRRPELLTTLEERIRTSVSGAVGQQLVDLMNSAIDARASVGVIGLATAAWVGLGWMWHLREALSQMWAHPVAPAGYLRTKLSDLAAMVGTFVVIVATIALTVLGHARPMAAVLRWLEIPQFSVFDEIFRGISVLVSVLVSWVLFTWMIGRLPREPVGLVTAARAGLMAAVGFELFKQVGAIYLQIVLRSPAGAVFGPVLGLMVFAFVTAWLILFATAWAATASA
>NC_020559.1|WP_003417619.1|3726370_3726628_-|DUF3017-domain-containing-protein
MTVRAVLRRTVGAQWPILAGVNFWRRGALLIGIGVGVAAVLRLVLSEERAGLLVVRSKGIDFVTTVTVAAAMVYIASTIDPLGTG
>NC_020559.1|WP_015345175.1|3726883_3736357_-|PPE-family-protein
MNFPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGAAAAAMAAAAAPYAGWLGSVAAQAVAVAGQARAAVAAFEAALAATVDPAAVAVNRMAMRALAMSNLLGQNAAAIAAVEAEYELMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVGAFLNALFAGPAKMLRLNAGLGNVGNYNVGLGNVGIFNLGAANVGAQNLGAANAGSGNFGFGNIGNANFGFGNSGLGLPPGMGNIGLGNAGSSNYGLANLGVGNIGFANTGSNNIGIGLTGDNLTGIGGLNSGTGNLGLFNSGTGNIGFFNSGTGNFGVFNSGSYNTGVGNAGTASTGLFNVGGFNTGVANVGSYNTGSFNAGNTNTGGFNPGNVNTGWLNTGNTNTGIANSGNVNTGAFISGNFSNGVLWRGDYEGLWGLSGGSTIPAIPIGLELNGGVGPITVLPIQILPTIPLNIHQTFSLGPLVVPDIVIPAFGGGTAIPISVGPITISPITLFPAQNFNTTFPVGPFFGLGVVNISGIEIKDLAGNVTLQLGNLNIDTRINQSFPVTVNWSTPAVTIFPNGISIPNNPLALLASASIGTLGFTIPGFTIPAAPLPLTIDIDGQIDGFSTPPITIDRIPRNLGASVTVGPILINGVNIPATPGFGNTTTAPSSGFFNSGDGGVSGFGNFGAGSSGWWNQAQTEVAGAGSGFANFGSLGSGVLNFGSGVSGLYNTGGLPPGTPAVVSGIGNVGEQLSGLSSAGTALNQSLIINLGLADVGSVNVGFGNVGDFNLGAANIGDLNVGLGNVGGGNVGFGNIGDANFGLGNAGLAAGLAGVGNIGLGNAGSGNVGFGNMGVGNIGFGNTGTNNLGIGLTGDNQTGIGGLNSGAGNIGLFNSGTGNVGLFNSGTGNFGLFNSGSFNTGIGNGGTGSTGLFNAGNFNTGVANPGSYNTGSFNVGDTNTGGFNPGSINTGWFNTGNANTGVANSGNVDTGALMSGNFSNGILWRGNFEGLFGLNVGITIPEFPIHWTSTGGIGPIIIPDTTILPPIHLGLTGQANYGFAVPDIPIPAIHIDFDGAADAGFTAPATTLLSALGITGQFRFGPITVSNVQLNPFNVNLKLQFLHDAFPNEFPDPTISVQIQVAIPLTSATLGGLALPLQQTIDAIELPAISFSQSIPIDIPPIDIPASTINGISMSEVVPIDVSVDIPAVTITGTRIDPIPLNFDVLSSAGPINISIIDIPALPGFGNSTELPSSGFFNTGGGGGSGIANFGAGVSGLLNQASSPMVGTLSGLGNAGSLASGVLNSGVDISGMFNVSTLGSAPAVISGFGNLGNHVSGVSIDGLLAMLTSGGSGGSGQPSIIDAAIAELRHLNPLNIVNLGNVGSYNLGFANVGDVNLGAGNLGNLNLGGGNLGGQNLGLGNLGDGNVGFGNLGHGNVGFGNSGLGALPGIGNIGLGNAGSNNVGFGNMGLGNIGFGNTGTNNLGIGLTGDNQTGFGGLNSGAGNLGLFNSGTGNIGFFNTGTGNWGLFNSGSYNTGIGNSGTGSTGLFNAGSFNTGLANAGSYNTGSLNAGNTNTGGFNPGNVNTGWFNAGHTNTGGFNTGNVNTGAFNSGSFNNGALWTGDHHGLVGFSYSIEITGSTLVDINETLNLGPVHIDQIDIPGMSLFDIHELVNIGPFRIEPIDVPAVVLDIHETMVIPPIVFLPSMTIGGQTYTIPLDTPPAPAPPPFRLPLLFVNALGDNWIVGASNSTGMSGGFVTAPTQGILIHTGPSSATTGSLALTLPTVTIPTITTSPIPLKIDVSGGLPAFTLFPGGLNIPQNAIPLTIDASGVLDPITIFPGGFTIDPLPLSLALNISVPDSSVPIIIVPPTPGFGNATATPSSGFFNSGAGGVSGFGNFGAGSSGWWNQAHAALAGAGSGVLNVGTLNSGVLNVGSGISGLYNTAIVGLGTPALVSGAGNVGQQLSGVLAAGTALTQSPIINLGLADVGNYNLGLGNVGDFNLGAANLGDLNLGLGNIGNANVGFGNIGHGNVGFGNSGLGAALGIGNIGLGNAGSTNVGLANMGVGNIGFANTGTNNLGIGLTGDNQTGIGGLNSGAGNIGLFNSGTGNIGFFNTGTGNWGLFNSGSYNTGIGNSGTGSTGLFNAGSFNTGLANAGSYNTGSFNVGDTNTGGFNPGSINTGWFNTGNANTGIANSGNVDTGALMSGNFSNGILWRGNYEGLFSYSYSLDVPRITILDAHFTGAFGPVVVPPIPVPAINAHLTGNAAMGAFTIPQIDIPALNPNVTGSVGFGPIAVPSVTIPALTAARAVLDMAASVGATSEIEPFIVWTSSGAIGPTWYSVGRIYNAGDLFVGGNIISGIPTLSTTGPVHAVFNAASQAFNTPALNIHQIPLGFQVPGSIDAITLFPGGLTFPANSLLNLDVFVGTPGATIPAITFPEIPANADGELYVIAGDIPLINIPPTPGIGNTTTVPSSGFFNTGAGGGSGFGNFGANMSGWWNQAHTALAGAGSGIANVGTLHSGVLNLGSGLSGIYNTSTLPLGTPALVSGLGNVGDHLSGLLASNVGQNPITIVNIGLANVGNGNVGLGNIGNLNLGAANIGDVNLGFGNIGDVNLGFGNIGGGNVGFGNIGDANFGFGNSGLAAGLAGMGNIGLGNAGSGNVGWANMGLGNIGFGNTGTNNLGIGLTGDNQSGIGGLNSGTGNIGLFNSGTGNIGFFNSGTANFGLFNSGSYNTGIGNSGVASTGLVNAGGFNTGVANAGSYNTGSFNAGDTNTGGFNPGSTNTGWFNTGNANTGVVNAGNVNTGALITGNFSNGILWRGNYEGLAGFSFGYPIPLFPAVGADVTGDIGPATIIPPIHIPSIPLGFAAIGHIGPISIPNIAIPSIHLGIDPTFDVGPITVDPITLTIPGLSLDAAVSEIRMTSGSSSGFKVRPSFSFFAVGPDGMPGGEVSILQPFTVAPINLNPTTLHFPGFTIPTGPIHIGLPLSLTIPGFTIPGGTLIPQLPLGLGLSGGTPPFDLPTVVIDRIPVELHASTTIGPVSLPIFGFGGAPGFGNDTTAPSSGFFNTGGGGGSGFSNSGSGMSGVLNAISDPLLGSASGFANFGTQLSGILNRGAGISGVYNTGTLGLVTSAFVSGFMNVGQQLSGLLFAGTGP
>NC_020559.1|WP_049961743.1|3736982_3737429_+|transposase
MDAAITACHHIAIRDDVGARSIRFSVEPTLAGLRTLTDKLSGYDDIDATVEPTSMTWLPLTIAVENAGDTMHMAGARHCARLRGAIVGKSKSDVIDAEVLTRASEVFDLTPLTLPTPAQLALRRSVIRRAGAVIDANRSWRRLMSLAR
>NC_020559.1|WP_003900675.1|3737465_3738206_-|transposase
MAIDPAAAYASAIRTPGLLPNAKLVVDHFHVTTLANDALTAVRRRVTWAFHDRRGRKIDPQWANRRRLLTARERLSDKSFAKMRNRINAVDPRAQILSAWIAKEELRTLLSTVRTGGDPHLARHHLHRFLPGASTRRSPNCSPWPPPLTSHPRSTPSWSPASPTRASVVGEVAEMLGDIDGQCVQVEVPVPERGPAGCGGLDGLGRAGVSATPRVCAAMTAVNVAGRCAGQQADVGPTPQHRCRGR
>NC_020559.1|WP_009938650.1|3738500_3738788_-|hypothetical-protein
MSRRRRRARRAGVVSISVKEYAVTSPKDLPYGEDRIMVRWNKIRWRCREDYCKLGPFTEAITQVPARVRSTLRLRRQMAKAIGDAARSVGRGRPG
>NC_020559.1|WP_003417738.1|3750506_3751301_-|BBE-domain-containing-protein
MLASCPARSGAAVADAIKSAVGVQPSGVEHKTLRRMDLVRYLAGGHTTYPPEGFVAGSDVIGTTNPAAAQAIVAAIGTWPPAAGRASALIDSLGGAVGDMDPEGSAFPWCRQSAVVQWYVNTPSDGQVATANKWLSDAHHAVQHFSVGGYVNYLEANAAASQYFGANLSRLTTVRRKYDPDRIMYSGLDFSTRQVAERLLPALGFRVRFGVLVIRCALCTDTVKRLGTLPNLTWSRLKVNVAVTQEQAGVMDLPALPVRRTPRR
>NC_020559.1|WP_003417739.1|3751382_3751754_-|FAD-binding-oxidoreductase
MSAATDLYAVHQALAGESRAIPTGSCPTVGVAGLTLGGGLGADSRHAGLTCDALKSATVVLPGGDAVSASADDHAELFWALRGGGGGNFGVTTSMTFARFPTADCDVVRVDFAPSAAAQVLVG
>NC_020559.1|WP_157132559.1|3751651_3751870_-|hypothetical-protein
MRGGGHSYIGASSANGAMVLDLLGLPGGVHFDSATRNVRCRPRPISMRSIKRWPVRAGRFRPAAARPWVWRV
>NC_020559.1|WP_003417741.1|3751896_3752157_-|hypothetical-protein
MSRQTFLRGAVGAPATSAVFPTILARATPGDGWASLASSIGGQVLLPANGRAFTSGKQIFNSNYSGLNPAAVVTVASQADVRKAVS
>NC_020559.1|WP_003417745.1|3752271_3752661_+|DUF732-domain-containing-protein
MNLRRHQTLTLRLLAASAGILSAAAFAAPAQANPVDDAFIAALNNAGVNYGDPVDAKALGQSVCPILAEPGGSFNTAVASVVARAQGMSQDMAQTFTSIAISMYCPSVMADVASGNLPALPDMPGLPGS

Crispr_ID: NC_020559_16

• CRISPR_ID: NC_020559_16
• CRISPR_location: 3829797-3829886
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020559_16

Consensus_repeat	Method
CCAGGCGTTGGGCTGGCTGCCGAT	CRISPRCasFinder

spacers of NC_020559_16

>16.1|3829821|42|NC_020559|CRISPRCasFinder
GCAGGACATCGACGCCGCCGCGGAGGCCGCGGCCCAGCCAAG

CRISPR arrays and Neighbor proteins around NC_020559_16

CRISPR arrays

The CRISPR arrays of NC_020559_16

>merge|NC_020559|16|3829797-3829886|CRISPRCasFinder
CCAGGCGTTGGGCTGGCTGCCGATGCAGGACATCGACGCCGCCGCGGAGGCCGCGGCCCAGCCAAGCCACGCGTTGGGCTGGCTGCCGAT

>NC_020559|16|10|3829797-3829886|CRISPRCasFinder
CCAGGCGTTGGGCTGGCTGCCGAT	GCAGGACATCGACGCCGCCGCGGAGGCCGCGGCCCAGCCAAG
CCACGCGTTGGGCTGGCTGCCGAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_078450940.1|3830871_3831234_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003900053.1|3831396_3831933_+|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_020559.1|WP_003904310.1|3823525_3823888_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003418284.1|3837446_3838160_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003900057.1|3841142_3841619_+|DUF2510-domain-containing-protein	unknown	unknown	gnl|CDD|378480
NC_020559.1|WP_003901633.1|3824050_3824581_+|PPE-family-protein	unknown	unknown	gnl|CDD|227938
NC_020559.1|WP_003418277.1|3834603_3835986_-|glutamate-decarboxylase	unknown	unknown	gnl|CDD|130848
NC_020559.1|WP_003908241.1|3827862_3828081_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003418289.1|3839246_3841121_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl|CDD|234729
NC_020559.1|WP_003912231.1|3836023_3837445_-|NAD(P)H-hydrate-dehydratase	unknown	unknown	gnl|CDD|366541
NC_020559.1|WP_003901635.1|3828575_3828875_+|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_020559.1|WP_003917789.1|3833255_3833411_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003418266.1|3833075_3833231_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003418141.1|3828960_3829503_+|PPE-family-protein	unknown	unknown	gnl|CDD|227938
NC_020559.1|WP_003900685.1|3823191_3823422_+|histone-acetyltransferase	unknown	unknown	unknown
NC_020559.1|WP_100208666.1|3825695_3827870_-|IS21-family-transposase	unknown	unknown	gnl|CDD|224401
NC_020559.1|WP_023641626.1|3838170_3839025_-|DUF4436-domain-containing-protein	unknown	unknown	gnl|CDD|379624
NC_020559.1|WP_003418122.1|3824847_3825378_+|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_020559.1|WP_003418047.1|3822005_3823232_-|alanine-racemase	unknown	unknown	gnl|CDD|234600
NC_020559.1|WP_003418042.1|3821502_3822009_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	unknown	unknown	gnl|CDD|223873

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_003900053.1|3831396_3831933_+|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	4.42683e-51
NC_020559.1|WP_003900057.1|3841142_3841619_+|DUF2510-domain-containing-protein	gnl|CDD|378480	pfam10708, DUF2510, Protein of unknown function (DUF2510). This is family of proteins conserved in Actinobacteria. Many members are annotated as putative membrane proteins but this could not be confirmed.	9.72562e-06
NC_020559.1|WP_003418277.1|3834603_3835986_-|glutamate-decarboxylase	gnl|CDD|130848	TIGR01788, Glutamate_decarboxylase_alpha_GAD-alpha., glutamate decarboxylase. This model represents the pyridoxal phosphate-dependent glutamate (alpha) decarboxylase found in bacteria (low and hi-GC gram positive, proteobacteria and cyanobacteria), plants, fungi and at least one archaon (Methanosarcina). The product of the enzyme is gamma-aminobutyrate (GABA).	0
NC_020559.1|WP_003418289.1|3839246_3841121_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl|CDD|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NC_020559.1|WP_003912231.1|3836023_3837445_-|NAD(P)H-hydrate-dehydratase	gnl|CDD|366541	pfam01256, Carb_kinase, Carbohydrate kinase. This family is related to pfam02110 and pfam00294 implying that it also is a carbohydrate kinase. (personal obs Yeats C).	1.1782e-79
NC_020559.1|WP_003901635.1|3828575_3828875_+|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	2.69547e-09
NC_020559.1|WP_003418042.1|3821502_3822009_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	gnl|CDD|223873	COG0802, COG0802, Predicted ATPase or kinase [General function prediction only].	1.1096e-49
NC_020559.1|WP_003418141.1|3828960_3829503_+|PPE-family-protein	gnl|CDD|227938	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion].	2.96716e-30
NC_020559.1|WP_003901633.1|3824050_3824581_+|PPE-family-protein	gnl|CDD|227938	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion].	4.32277e-46
NC_020559.1|WP_100208666.1|3825695_3827870_-|IS21-family-transposase	gnl|CDD|224401	COG1484, DnaC, DNA replication protein [DNA replication, recombination, and repair].	8.34754e-65
NC_020559.1|WP_003418122.1|3824847_3825378_+|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	2.48288e-52
NC_020559.1|WP_003418047.1|3822005_3823232_-|alanine-racemase	gnl|CDD|234600	PRK00053, alr, alanine racemase; Reviewed.	2.56905e-175
NC_020559.1|WP_023641626.1|3838170_3839025_-|DUF4436-domain-containing-protein	gnl|CDD|379624	pfam14494, DUF4436, Domain of unknown function (DUF4436). This is a family of membrane and transmembrane proteins from mycobacterial and related species. The function is not known.	2.26585e-111

Protein sequences

>NC_020559.1|WP_003418141.1|3828960_3829503_+|PPE-family-protein
MPFTLTPAHQISYQMYAGPGADSMRAASQQLRELAFSADTTADSLNDTLFDLDDTWIGGSSAFMTDAALRYLKWLSKHSKRLWQTANTIHHLANTYEDIRQRVVPPAAIEDNREEVRRLIASDITGENAPAIAELDEQYQSYGDTNVQAMNLYAERAQTLLSQLPRWQEPPQIHQRGRGG
>NC_020559.1|WP_003901635.1|3828575_3828875_+|PE-family-protein
MSFIFTTPQALDNAAKSVSGIHDLWLADSKTAITVVNAIVPPAADPVSNRMVGRILEHMAQYQQISSQALEYLRGFSQGLAENAEAYRLAEAQNSTTFD
>NC_020559.1|WP_003908241.1|3827862_3828081_-|hypothetical-protein
MARRSILMLDLVELLTHWHAGRSQVRLSESLGIDRKTVRKYTAPAIAAGIEPGGEPLSAEQWAELIGGWFPE
>NC_020559.1|WP_100208666.1|3825695_3827870_-|IS21-family-transposase
MNDPAARASTWPLIAPHHDRIKDWLDADVTVATIAQRLRDDHGVAASESSVRRWIATHFAEEVARERVTVPRGPVDAGSEAQIDYGRLGMWFDPATARRVAVWAFVMVLAFSRHLFVRPVIRMDQTAWCACHVAAFEFFDGVPARLVCDNLRTGVDKPDLYDPQINRSYAELASHYATLVDPARARKPKDKPRVERPMTYVRDSFWKGREFDSLAQMQQAAVTWSTEVAGLRYLRALEGAQPLRMFEAVEQQALIALPPRAFELTSWSIGTVGVDTHLKVGKALYSVPWRLIGQRLHARTAGDVVQIFAGNDVVATHVRRPSGRSTDFSHYPPEKIAFHMRTPTWCRHTAELVGPACQQVIAEFMRDNAIHHLRSAQGVLGLRDKHGCDRLEAACARAIEVGDPSYRTIKGILVAGTEHAANEPTTSSPASTAGAFLRGPEQFGTDTPRRLISQRNPEPSRHNPHRYSQGEASMSICDPALRNALRTLKLSGMLDTLDARLAQTRNGDLGHLEFLQALREDEIARRESAALTRRLRRAKFEAQATFEDFDFTANPKLPGAMLRDLAALRWLDAGESVILHGPVGVGKTHVAQALVHAVARRGGDVRFAKTSRMLSDLAGGHADRSWGQRIREYTKPLVLILDDFAMREHTAMHADDLYELISDRAITGKPLILTSNRAPNNWYGLFPNPVVAESLLDRLINTSHQILMDGPSYRPRKRPGRTTS
>NC_020559.1|WP_003418122.1|3824847_3825378_+|PPE-family-protein
MHLMIPAEYISNVIYEGPRADSLYAADQRLRQLADSVRTTAESLNTTLDELHENWKGSSSEWMADAALRYLDWLSKHSRQILRTARVIESLVMAYEETLLRVVPPATIANNREEVRRLIASNVAGVNTPAIADLEAQYEQYRAENIQAMDRYLSWTRFALSKLPRWREPPQIHRSG
>NC_020559.1|WP_003901633.1|3824050_3824581_+|PPE-family-protein
MHPMIPAEYISNIIYEGPGADSLFFASGQLRELAYSVETTAESLEDELDELDENWKGSSSDLLADAVERYLQWLSKHSSQLKHAAWVINGLANAYNDTRRKVVPPEEIAANREERRRLIASNVAGVNAPAIADLDAQYDQYRARNVAVMNAYVSWTRSALSDLPRWREPPQIYRGG
>NC_020559.1|WP_003904310.1|3823525_3823888_-|hypothetical-protein
MPNPVTMLYGRKADLVILPHVLAEERPHPYSTPGRKRGAQIALTTGIDALASFAPQIVNPRHGLSRVVQCLGGCENKRHAYFRSISKTPHIRARGVPSVCAVRTVGVDGAKRPPKPIPVQ
>NC_020559.1|WP_003900685.1|3823191_3823422_+|histone-acetyltransferase
MSFGFPTFSQNRFTEQYSGLCPIAPGRGAGLQPCRRDCPVARWLVADHPVFGSDCRCRMMVGVNRVRIGRHELTGA
>NC_020559.1|WP_003418047.1|3822005_3823232_-|alanine-racemase
MKRFWENVGKPNDTTDGRGTTSLAMTPISQTPGLLAEAMVDLGAIEHNVRVLREHAGHAQLMAVVKADGYGHGATRVAQTALGAGAAELGVATVDEALALRADGITAPVLAWLHPPGIDFGPALLADVQVAVSSLRQLDELLHAVRRTGRTATVTVKVDTGLNRNGVGPAQFPAMLTALRQAMAEDAVRLRGLMSHMVYADKPDDSINDVQAQRFTAFLAQAREQGVRFEVAHLSNSSATMARPDLTFDLVRPGIAVYGLSPVPALGDMGLVPAMTVKCAVALVKSIRAGEGVSYGHTWIAPRDTNLALLPIGYADGVFRSLGGRLEVLINGRRCPGVGRICMDQFMVDLGPGPLDVAEGDEAILFGPGIRGEPTAQDWADLVGTIHYEVVTSPRGRITRTYREAENR
>NC_020559.1|WP_003418042.1|3821502_3822009_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE
MSREGIRRRPKARAGLTGGGTATLPRVEDTLTLGSRLGEQLCAGDVVVLSGPLGAGKTVLAKGIAMAMDVEGPITSPTFVLARMHRPRRPGTPAMVHVDVYRLLDHNSADLLSELDSLDLDTDLEDAVVVVEWGEGLAERLSQRHLDVRLERVSHSDTRIATWSWGRS
>NC_020559.1|WP_078450940.1|3830871_3831234_-|hypothetical-protein
MPNPVTMLYGRKADLVILPHVLAEERPHPYSTPGRKRGAQIALTTGIDALASFAPQIVNPRHGLSRVVQCLGGCENKRHAYFRSISKTPHIRAKGVPSVCAVRTVGVDGAKRPPKPIPVQ
>NC_020559.1|WP_003900053.1|3831396_3831933_+|PPE-family-protein
MHPMIPAEYISNIIYEGPGADSLSAAAEQLRLMYNSANMTAKSLTDRLGELQENWKGSSSDLMADAAGRYLDWLTKHSRQILETAYVIDFLAYVYEETRHKVVPPATIANNREEVHRLIASNVAGVNTPAIAGLDAQYQQYRAQNIAVMNDYQSTARFILAYLPRWQEPPQIYGGGGG
>NC_020559.1|WP_003418266.1|3833075_3833231_-|hypothetical-protein
MAALSARRGPKPGKAGANAADAEIAWLRAELDTAREVIRVQGELSALLERL
>NC_020559.1|WP_003917789.1|3833255_3833411_-|hypothetical-protein
MPDPQVPERAQRRTFTVKYKLAILDEYDRADRTERGAILRRENLYSSLLTE
>NC_020559.1|WP_003418277.1|3834603_3835986_-|glutamate-decarboxylase
MSRSHPSVPAHSIAPAYTGRMFTAPVPALRMPDESMDPEAAYRFIHDELMLDGSSRLNLATFVTTWMDPEAEKLMAETFDKNMIDKDEYPATAAIEARCVSMVADLFHAEGLRDHDPTSATGVSTIGSSEAVMLGGLALKWRWRQRVGSWKGRMPNLVMGSNVQVVWEKFCRYFDVEPRYLPMERGRYVITPEQVLAAVDENTIGVVAILGTTYTGELEPIAEICAALDKLAAGGGVDVPVHVDAASGGFVVPFLHPDLVWDFRLPRVVSINVSGHKYGLTYPGVGFVVWRGPEHLPEDLVFRVNYLGGDMPTFTLNFSRPGNQVVGQYYNFLRLGRDGYTKVMQALSHTARWLGDQLREVDHCEVISDGSAIPVVSFRLAGDRGYTEFDVSHELRTFGWQVPAYTMPDNATDVAVLRIVVREGLSADLARALHDDAVTALAALDKVKPGGHFDAQHFAH
>NC_020559.1|WP_003912231.1|3836023_3837445_-|NAD(P)H-hydrate-dehydratase
MRHYYSVDTIRAAEAPLLASLPDGALMRRAAFGLATEIGRELTARTGGVVGRRVCAVVGSGDNGGDALWAATFLRRRGAAADAVLLNPDRTHRKALAAFTKSGGRLVESVSAATDLVIDGVVGISGSGPLRPAAAQVFAAVQAAAIPVVAVDIPSGIDVATGAITGPAVHAALTVTFGGLKPVHALADCGRVVLVDIGLDLAHTDVLGFEATDVAARWPVPGPRDDKYTQGVTGVLAGSSTYPGAAVLCTGAAVAATSGMVRYAGTAHAEVLAHWPEVIASPTPAAAGRVQAWVVGPGLGTDEAGAAALWFALDTDLPVLVDADGLTMLADHPDLVAGRNAPTVLTPHAGEFARLAGAPPGDDRVGACRQLADALGATVLLKGNVTVIADPGGPVYLNPAGQSWAATAGSGDVLSGMIGALLASGLPSGEAAAAAAFVHARASAAAAADPGPGDAPTSASRISGHIRAALAAL
>NC_020559.1|WP_003418284.1|3837446_3838160_-|hypothetical-protein
MADASVVARLRSWALAVWHFVSNAPLTYAWLVVLVITTIIQNNLTGSQLHFVLLHRSTNIAELGRDPLEVLFSSLLWIDGRNLEPYLLLFTLFLAPAEHWLGHLRWLTVGLTAHIGATYLSEGLLYLAIQHRDASERMVHARDIGVSYFLVGVMAVLTYHIAKPWRWGYLGVLLVIFGFPLIAMDKAELDFTAVGHFASILIGLLFYPMARERDGRLWNPARIKSLLHRRGTRGRRA
>NC_020559.1|WP_023641626.1|3838170_3839025_-|DUF4436-domain-containing-protein
MGRILRVVVGLVLVIAAYVTVIALYHSTGLGRPHEVAHGRPTADGTTVTLHVEQLQTIKGVLVANLAVSPGTELLDSQTQGLKDDLTVTVTSVVTPTKRTWSSGSLPGVFPVPLTISGDPANWPFDHYRSGPITVQLYRGAAHAPERVSVTFVDRLPGWNVDISGVGDANVPAPYRVGLHRSPSSVAFGTVIVGVLIALAGVGLFVVVQTARGRRQFQPPMTTWYAAMLFAVIPLRNALPDAPPIGFWIDVTVVLWVVVALVTSMVLYILCWWWHLKPDVDETM
>NC_020559.1|WP_003418289.1|3839246_3841121_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYVGRRPAYVVVMDALRRMEYRGYDSSGIALVDGGTLTVRRRAGRLANLEEAVAEMPSTALSGTTGLGHTRWATHGRPTDRNAHPHRDAAGKIAVVHNGIIENFAVLRRELETAGVEFASDTDTEVAAHLVARAYRHGETADDFVGSVLAVLRRLEGHFTLVFANADDPGTLVAARRSTPLVLGIGDNEMFVGSDVAAFIEHTREAVELGQDQAVVITADGYRISDFDGNDGLQAGRDFRPFHIDWDLAAAEKGGYEYFMLKEIAEQPAAVADTLLGHFVGGRIVLDEQRLSDQELREIDKVFVVACGTAYHSGLLAKYAIEHWTRLPVEVELASEFRYRDPVLDRSTLVVAISQSGETADTLEAVRHAKEQKAKVLAICNTNGSQIPRECDAVLYTRAGPEIGVASTKTFLAQIAANYLLGLALAQARGTKYPDEVEREYHELEAMPDLVARVIAATGPVAELAHRFAQSSTVLFLGRHVGYPVALEGALKLKELAYMHAEGFAAGELKHGPIALIEDGLPVIVVMPSPKGSATLHAKLLSNIREIQTRGAVTIVIAEEGDETVRPYADHLIEIPAVSTLLQPLLSTIPLQVFAASVARARGYDVDKPRNLAKSVTVE
>NC_020559.1|WP_003900057.1|3841142_3841619_+|DUF2510-domain-containing-protein
MVGRAVPSPNRRYRRVWPPRTKGQHLSNPYAQHQLKLIRHTGALILWQQRTYVVSGTREQCEAAYKSAQTYNLLVGWWSLVSLLAMNWIALISNFNAIRRVRAAADGASVPHGPHAIAHPAVPRGPIPAGWYPDPSGAGLRYWDGATWTHWTHPPRHR

Crispr_ID: NC_020559_17

• CRISPR_ID: NC_020559_17
• CRISPR_location: 4091415-4091503
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_020559_17

Consensus_repeat	Method
GCTCGGCGACGATGCGGGCCGGATGACGGCC	CRISPRCasFinder

spacers of NC_020559_17

>17.1|4091446|27|NC_020559|CRISPRCasFinder
CGAGGAGGAGCCGAGCAATCGAACCGA

CRISPR arrays and Neighbor proteins around NC_020559_17

CRISPR arrays

The CRISPR arrays of NC_020559_17

>merge|NC_020559|17|4091415-4091503|CRISPRCasFinder
GCTCGGCGACGATGCGGGCCGGATGACGGCCCGAGGAGGAGCCGAGCAATCGAACCGAGCTCGGCGACGATGCGGGCCGGATGACGGCC

>NC_020559|17|11|4091415-4091503|CRISPRCasFinder
GCTCGGCGACGATGCGGGCCGGATGACGGCC	CGAGGAGGAGCCGAGCAATCGAACCGA
GCTCGGCGACGATGCGGGCCGGATGACGGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_020559.1|WP_003419718.1|4094257_4095079_-|CoA-pyrophosphatase	unknown	unknown	gnl|CDD|239518
NC_020559.1|WP_003419721.1|4095210_4095894_-|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl|CDD|239264
NC_020559.1|WP_003899631.1|4088528_4090484_+|acetate--CoA-ligase	unknown	unknown	gnl|CDD|234677
NC_020559.1|WP_003419708.1|4090519_4091218_-|protease	unknown	unknown	unknown
NC_020559.1|WP_003419701.1|4085267_4086194_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NC_020559.1|WP_003419728.1|4097214_4097889_+|cAMP-activated-global-transcriptional-regulator-CRP	unknown	unknown	gnl|CDD|223736
NC_020559.1|WP_003899629.1|4086195_4087821_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173853
NC_020559.1|WP_003900733.1|4082768_4084415_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224048
NC_020559.1|WP_003419733.1|4098793_4099249_-|RidA-family-protein	unknown	unknown	gnl|CDD|100006
NC_020559.1|WP_003900734.1|4093058_4094252_-|acid-resistance-serine-protease-MarP	unknown	unknown	gnl|CDD|379142
NC_020559.1|WP_003899626.1|4082001_4082772_-|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003419731.1|4097992_4098787_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293836
NC_020559.1|WP_003419710.1|4091563_4092082_+|phage-holin-family-protein	unknown	unknown	gnl|CDD|377816
NC_020559.1|WP_003899635.1|4096738_4097116_+|hypothetical-protein	unknown	unknown	unknown
NC_020559.1|WP_003419724.1|4095893_4096631_-|endonuclease-III	unknown	unknown	gnl|CDD|223255
NC_020559.1|WP_003899628.1|4084411_4085275_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NC_020559.1|WP_003899624.1|4077672_4078836_-|TadA-family-conjugal-transfer-associated-ATPase	unknown	unknown	gnl|CDD|200328
NC_020559.1|WP_003419712.1|4092082_4093066_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NC_020559.1|WP_003900732.1|4078832_4079885_-|septum-site-determining-protein-Ssd	unknown	unknown	gnl|CDD|274798
NC_020559.1|WP_003419689.1|4080383_4081247_+|HAD-IB-family-hydrolase	unknown	unknown	gnl|CDD|273654

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_020559.1|WP_003419718.1|4094257_4095079_-|CoA-pyrophosphatase	gnl|CDD|239518	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative stress. CoAse has a conserved Nudix fold and requires a single divalent cation for catalysis. In addition to a signature Nudix motif G[X5]E[X7]REUXEEXGU, where U is Ile, Leu, or Val, CoAse contains an additional motif upstream called the NuCoA motif (LLTXT(SA)X3RX3GX3FPGG) which is postulated to be involved in CoA recognition. CoA plays a central role in lipid metabolism. It is involved in the initial steps of fatty acid sythesis in the cytosol, in the oxidation of fatty acids and the citric acid cycle in the mitochondria, and in the oxidation of long-chain fatty acids in peroxisomes. CoA has the important role of activating fatty acids for further modification into key biological signalling molecules.	1.20605e-47
NC_020559.1|WP_003419721.1|4095210_4095894_-|TlpA-family-protein-disulfide-reductase	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.72736e-22
NC_020559.1|WP_003899631.1|4088528_4090484_+|acetate--CoA-ligase	gnl|CDD|234677	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional.	0
NC_020559.1|WP_003900732.1|4078832_4079885_-|septum-site-determining-protein-Ssd	gnl|CDD|274798	TIGR03815, CpaE_hom_Actino, helicase/secretion neighborhood CpaE-like protein. Members of this protein family belong to the MinD/ParA family of P-loop NTPases, and in particular show homology to the CpaE family of pilus assembly proteins (see ). Nearly all members are found, not only in a gene context consistent with pilus biogenesis or a pilus-like secretion apparatus, but also near a DEAD/DEAH-box helicase, suggesting an involvement in DNA transfer activity. The model describes a clade restricted to the Actinobacteria.	4.37512e-92
NC_020559.1|WP_003419701.1|4085267_4086194_-|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	7.57934e-99
NC_020559.1|WP_003419728.1|4097214_4097889_+|cAMP-activated-global-transcriptional-regulator-CRP	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	2.11707e-55
NC_020559.1|WP_003899629.1|4086195_4087821_-|ABC-transporter-substrate-binding-protein	gnl|CDD|173853	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain of nickel/dipeptide/oligopeptide transport systems, which function in the import of nickel and peptides, and other closely related proteins. The oligopeptide-binding protein OppA is a periplasmic component of an ATP-binding cassette (ABC) transport system OppABCDEF consisting of five subunits: two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Similar to the ABC-type dipeptide and oligopeptide import systems, nickel transporter is comprised of five subunits NikABCDE: the two pore-forming integral inner membrane proteins NikB and NikC; the two inner membrane-associated proteins with ATPase activity NikD and NikE; and the periplasmic nickel binding NikA, which is the initial nickel receptor that controls the chemotactic response away from nickel. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand binding domains of ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	4.73988e-122
NC_020559.1|WP_003900733.1|4082768_4084415_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0
NC_020559.1|WP_003419733.1|4098793_4099249_-|RidA-family-protein	gnl|CDD|100006	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	7.62827e-68
NC_020559.1|WP_003899628.1|4084411_4085275_-|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.77559e-81
NC_020559.1|WP_003419731.1|4097992_4098787_-|MBL-fold-metallo-hydrolase	gnl|CDD|293836	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	3.29322e-75
NC_020559.1|WP_003419710.1|4091563_4092082_+|phage-holin-family-protein	gnl|CDD|377816	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III. Phage_holin_3_6 is a family of small hydrophobic proteins with two or three transmembrane domains of the Hol-X family. Holin proteins are produced by double-stranded DNA bacteriophages that use an endolysin-holin strategy to achieve lysis of their hosts. The endolysins are peptidoglycan-degrading enzymes that are usually accumulated in the cytosol until access to the cell wall substrate is provided by the holin membrane lesion.	8.41555e-32
NC_020559.1|WP_003419724.1|4095893_4096631_-|endonuclease-III	gnl|CDD|223255	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair].	2.16645e-106
NC_020559.1|WP_003900734.1|4093058_4094252_-|acid-resistance-serine-protease-MarP	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	1.86888e-19
NC_020559.1|WP_003899624.1|4077672_4078836_-|TadA-family-conjugal-transfer-associated-ATPase	gnl|CDD|200328	TIGR03819, heli_sec_ATPase, helicase/secretion neighborhood ATPase. Members of this protein family comprise a distinct clade of putative ATPase associated with an integral membrane complex likely to act in pilus formation, secretion, or conjugal transfer. The association of most members with a nearby gene for a DEAH-box helicase suggests a role in conjugal transfer.	1.05849e-164
NC_020559.1|WP_003419712.1|4092082_4093066_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.34553e-25
NC_020559.1|WP_003419689.1|4080383_4081247_+|HAD-IB-family-hydrolase	gnl|CDD|273654	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490. This hypothetical equivalog is a member of the IB subfamily (TIGR01488) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The sequences modelled here are all bacterial. The IB subfamily includes the enzyme phosphoserine phosphatase (TIGR00338). Due to this relationship, several of these sequences have been annotated as "phosphoserine phosphatase related proteins," or "Phosphoserine phosphatase-family enzymes." There is presently no evidence that any of the enzymes in this model possess PSPase activity. OMNI|NTL01ML1250 is annotated as a "possible transferase," however this is due to the C-terminal domain found on this sequence which is homologous to a group of glycerol-phosphate acyltransferases (between trusted and noise to TIGR00530). A subset of these sequences including OMNI|CC1962, the Caulobacter crescentus CicA protein cluster together and may represent a separate equivalog. [Unknown function, Enzymes of unknown specificity].	5.37865e-86

Protein sequences

>NC_020559.1|WP_003419708.1|4090519_4091218_-|protease
MQTAHRRFAAAFAAVLLAVVCLPANTAAADDKLPLGGGAGIVVNGDTMCTLTTIGHDKNGDLIGFTSAHCGGPGAQIAAEGAENAGPVGIMVAGNDGLDYAVIKFDPAKVTPVAVFNGFAINGIGPDPSFGQIACKQGRTTGNSCGVTWGPGESPGTLVMQVCGGPGDSGAPVTVDNLLVGMIHGAFSDNLPSCITKYIPLHTPAVVMSINADLADINAKNRPGAGFVPVPA
>NC_020559.1|WP_003899631.1|4088528_4090484_+|acetate--CoA-ligase
MSESTPEVSSSYPPPAHFAEHANARAELYREAEEDRLAFWAKQANRLSWTTPFTEVLDWSGAPFAKWFVGGELNVAYNCVDRHVEAGHGDRVAIHWEGEPVGDRRTLTYSDLLAEVSKAANALTDLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSVVFGGFTAAALQARIVDAQAKLLITADGQFRRGKPSPLKAAADEALAAIPDCSVEHVLVVRRTGIEMAWSEGRDLWWHHVVGSASPAHTPEPFDSEHPLFLLYTSGTTGKPKGIMHTSGGYLTQCCYTMRTIFDVKPDSDVFWCTADIGWVTGHTYGVYGPLCNGVTEVLYEGTPDTPDRHRHFQIIEKYGVTIYYTAPTLIRMFMKWGREIPDSHDLSSLRLLGSVGEPINPEAWRWYRDVIGGGRTPLVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDDHGDPLPPHTEGAQHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDKGYYFAGDGARIDPDGAIWVLGRIDDVMNVSGHRISTAEVESALVAHSGVAEAAVVGVTDETTTQAICAFVVLRANYAPHDRTAEELRTEVARVISPIARPRDVHVVPELPKTRSGKIMRRLLRDVAENRELGDTSTLLDPTVFDAIRAAK
>NC_020559.1|WP_003899629.1|4086195_4087821_-|ABC-transporter-substrate-binding-protein
MVRQMRAALAALATGLLVLAPVAGCGGGVLSPDVVLVNGGEPPNPLIPTGTNDSNGGRIIDRLFAGLMSYDAVGKPSLEVAQSIESADNVNYRITVKPGWKFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGFDDVAGAPGDKSRTTMSGLRVVNDLEFTVRLKAPTIDFTLRLGHSSFYPLPDSAFRDMAAFGRNPIGNGPYKLADGPAGPAWEHNVRIDLVPNPDYHGNRKPRNKGLRFEFYANLDTAYADLLSGNLDVLDTIPPSALTVYQRDLGDHATSGPAAINQTLDTPLRLPHFGGEEGRLRRLALSAAINRPQICQQIFAGTRSPARDFTARSLPGFDPNLPGNEVLDYDPQRARRLWAQADAISPWSGRYAIAYNADAGHRDWVDAVANSIKNVLGIDAVAAPQPTFAGFRTQITNRAIDSAFRAGWRGDYPSMIEFLAPLFTAGAGSNDVGYINPEFDAALAAAEAAPTLTESHELVNDAQRILFHDMPVVPLWDYISVVGWSSQVSNVTVTWNGLPDYENIVKA
>NC_020559.1|WP_003419701.1|4085267_4086194_-|ABC-transporter-permease
MGWYVARRVAVMVPVFLGATLLIYGMVFLLPGDPVAALAGDRPLTPAVAAQLRSHYHLDDPFLVQYLRYLGGILHGDLGRAYSGLPVSAVLAHAFPVTIRLALIALAVEAVLGIGFGVIAGLRQGGIFDSAVLVTGLVIIAIPIFVLGFLAQFLFGVQLEIAPVTVGERASVGRLLLPGIVLGAMSFAYVVRLTRSAVAANAHADYVRTATAKGLSRPRVVTVHILRNSLIPVVTFLGADLGALMGGAIVTEGIFNIHGVGGVLYQAVTRQETPTVVSIVTVLVLIYLITNLLVDLLYAALDPRIRYG
>NC_020559.1|WP_003899628.1|4084411_4085275_-|ABC-transporter-permease
MAEHTGFWLDAWRGLRRRPKFVIAAALILLILVVAAFPSLFTAADPTYADPSQSMLAPSAAHWFGTDLQGHDIYSRTVYGARASVTVGLGATLAVFVVGGALGALAGFYGSWIDAVVSRVTDVFLGLPLLLAAIVLMQVMHHRTVWTVIAILALFGWPQVARIARGAVLEVRASDYVLAAKALGLNRFQILLRHALPNAVGPVIAVATVALGIFIVTEATLSYLGVGLPTSVVSWGGDINVAQTRLRSGSPILFYPAGALAITVLAFMMMGDALRDALDPASRAWRA
>NC_020559.1|WP_003900733.1|4082768_4084415_-|ABC-transporter-ATP-binding-protein
MSVPAAPLLSVEGLEVTFGTDAPAVCGVDLAVRSGQTVAVVGESGSGKSTTAAAILGLLPAGGRITAGRVVFDGRDITGADAKRLRSIRGREIGYVPQDPMTNLNPVWKVGFQVTEALRANTDGRAARRRAVELLAEAGLPDPAKQAGRYPHQLSGGMCQRALIAIGLAGRPRLLIADEPTSALDVTVQRQVLDHLQGLTDELGTALLLITHDLALAAQRAEAVVVVRRGVVVESGAAQSILQSPQHEYTRRLVAAAPSLTARSRRPPESRSRATTQAGDILVVSELTKIYRESRGAPWRRVESRAVDGVSFRLPRASTLAIVGESGSGKSTLARMVLGLLQPTSGTVVFDGTYDVGALARDQVLAFRRRVQPVFQNPYSSLDPMYSVFRAIEEPLRVHHVGDRRQRQRAVRELVDQVALPSSILGRRPRELSGGQRQRVAIARALALRPEVLVCDEAVSALDVLVQAQILDLLADLQADLGLTYLFISHDLAVIRQIADDVLVMRAGRVVEHASTEEVFSRPRHEYTRQLLQAIPGAPSAPRKVGNL
>NC_020559.1|WP_003899626.1|4082001_4082772_-|hypothetical-protein
MTVDPLAPLMELPGVAAASDRVRDALSRVHRHRANLRGWPVAAAEASLRAARASSVLDGGPARLHDAGAPTSGKPALSDPVFAGALRVGQALEGGAGPVVGVWRRAPLQALARLHMLAAADQVDDDRLGRPRSDADVGPRLELLADVVTHPTLASAPVVAAVAHGELLTLRPFGCADGVVARAVSRLVTIATGLDPHGLGVPEVIWMRQPAEYHDAARRFAGGTPDGVAGWLLLCCGAMLDGAREALSIAESLSPG
>NC_020559.1|WP_003419689.1|4080383_4081247_+|HAD-IB-family-hydrolase
MTVSDSPAQRQTPPQTPGGTAPRARTAAFFDLDKTIIAKSSTLAFSKPFFAQGLLNRRAVLKSSYAQFIFLLSGADHDQMDRMRTHLTNMCAGWDVAQVRSIVNETLHDIVTPLVFAEAADLIAAHKLCGRDVVVVSASGEEIVGPIARALGATHAMATRMIVEDGKYTGEVAFYCYGEGKAQAIRELAASEGYPLEHCYAYSDSITDLPMLEAVGHASVVNPDRGLRKEASVRGWPVLSFSRPVSLRDRIPAPSAAAIATTAAVGISALAAGAVTYALLRRFAFQP
>NC_020559.1|WP_003900732.1|4078832_4079885_-|septum-site-determining-protein-Ssd
MLTDPGLRDELDRVAAAVGVRVVHLGGRHPVSRKTWSAAAAVVLDHAAADRCGRLALPRRTHVSVLTGTEAATATWAAAITVGAQHVLRMPEQEGELVRELAEAAESARDDGICGAVVAVIGGRGGAGASLFAVALAQAAADALLVDLDPWAGGIDLLVGGETAPGLRWPDLALQGGRLNWSAVRAALPRPRGISVLSGTRRGYELDAGPVDAVIDAGRRGGVTVVCDLPRRLTDATQAALDAADLVVLVSPCDVRACAAAATMAPVLTAINPNLGLVVRGPSPGGLRAAEVADVAGVPLLASMRAQPRLAEQLEHGGLRLRRRSVLASAARRVLGVLPRAGSGRHGRAA
>NC_020559.1|WP_003899624.1|4077672_4078836_-|TadA-family-conjugal-transfer-associated-ATPase
MTGSLIERVRERLASESGPLRPSVVAAAIRAESGGMLGDTEVLANLRVLQTELTGAGILEPLLSADGTTDVLVTAPDSVWVDDGNGLRRSQIRFADESAVRRLAQRLALAAGRRLDDAQPWVDGQLTGIGVGGFAVRLHAVLPPVATQGTCLSLRVLRPATQDLAALAAAGAIDPAAAALVADIVTARLAFLVCGGTGAGKTTLLAAMLGAVSPDERIVCVEDAAELAPRHPHLVKLVARRANVEGIGEVTVRQLVRQALRMRPDRIVVGEVRGAEVVDLLAALNTGHEGGAGTVHANNPGEVPARMEALGALGGLDRAALHSQLAAAVQVLLHVARDRAGRRRLAEIAVLRQAEGRVQAVTVWHADRGMSDDAAALHDLLRSRASA
>NC_020559.1|WP_003419710.1|4091563_4092082_+|phage-holin-family-protein
MSKIDRKNGVPSTLTTIPLADPHAGPAEPSIGDLIKDATTQMSTLVRAEVELARAEITRDVKKGLTGSVFFISSLVVGFYSTFFFFFFVAELLDTWIWRWVAFLLVFAIMVVVTAVLALLGFLKVRRIRGPRQTIASVKETRTALTPGHDKTPVTPKPVTSDRATPVDPSGW
>NC_020559.1|WP_003419712.1|4092082_4093066_+|alpha/beta-hydrolase
MAAPDPSMTRIAGPWRHLDVHANGIRFHVVEAVPSGQPEGPDAATPPMQPALARPLVILLHGFGSFWWSWRHQLCGLTGARVVAVDLRGYGGSDKPPRGYDGWTLAGDTAGLIRALGHPSATLVGHADGGLACWTTALLHSRLVRAIALISSPHPAALRRSTLTRRDQRHALLPTLLRYQLPIWPERLLTRNNAAEIERLVRARGCAKWLASEDFSQAIDHLRQAIQIPAAAHCALEYQRWAVRSQLRSEGRRFIRAMTQQLGMPLLHLRGDADPYVLADPVERTQRYAPHGRYISIAGAGHFSHEEAPEEVNRHLMRFLEQVHQLS
>NC_020559.1|WP_003900734.1|4093058_4094252_-|acid-resistance-serine-protease-MarP
MTPSQWLDIAVLAVAFIAAISGWRAGALGSMLSFGGVLLGATAGVLLAPHIVSQISAPRAKLFAALFLILALVVVGEVAGVVLGRAVRGAIRNRPIRLIDSVIGVGVQLVVVLTAAWLLAMPLTQSKEQPELAAAVKGSRVLARVNEAAPTWLKTVPKRLSALLNTSGLPAVLEPFSRTPVIPVASPDPALVNNPVVAATEPSVVKIRSLAPRCQKVLEGTGFVISPDRVMTNAHVVAGSNNVTVYAGDKPFEATVVSYDPSVDVAILAVPHLPPPPLVFAAEPAKTGADVVVLGYPGGGNFTATPARIREAIRLSGPDIYGDPEPVTRDVYTIRADVEQGDSGGPLIDLNGQVLGVVFGAAIDDAETGFVLTAGEVAGQLAKIGATQPVGTGACVS
>NC_020559.1|WP_003419718.1|4094257_4095079_-|CoA-pyrophosphatase
MSAGGTPLQAGATPTGSRGTVALRPDAGPSWLRPLVDNVGQIPDAYRRRLPADVLAMVTAAGAVSAMTSSRRDHREAAVLVLFSGPEAGPGDGGVPDDADLLLTVRASTLRHHAGQAAFPGGVVDPADDGPVATALREANEETGIDPSRLHPLATMERTFIAPSRFHVVPVLAYSPDPGPVAVVNEAETAIVARVPVRAFINPANRLMVYRRPHTRRWAGPAFLLNQMLVWGFTGQVISAVLDVAGWAQPWDTGDIRELDAAMVLIDDESDPR
>NC_020559.1|WP_003419721.1|4095210_4095894_-|TlpA-family-protein-disulfide-reductase
MPSLPTTPAETAMTTLTGKTRWTIAILAVVAALMAALVAQLHDYSASSTISQRPAPREHRDGDTPEALAWSRQRANLPPCPAAGNGPGAAALRGVVVVCAGDGSAVDVARALAGRRVVINLWAHWCAPCMTELPVMAEYQRRVGPAVLVVTVHQGQNEAAALSRLADLGVRLPTLQDDRRRVAAALRVANVMPATVVLRPDGSVAQTLPRAFGSADEIVAAVGNDAG
>NC_020559.1|WP_003419724.1|4095893_4096631_-|endonuclease-III
MPGRWSAETRLALVRRARRMNRALAQAFPHVYCELDFTTPLELAVATILSAQSTDKRVNLTTPALFARYRTARDYAQADRTELESLIRPTGFYRNKAASLIGLGQALVERFGGEVPATMDKLVTLPGVGRKTANVILGNAFGIPGITVDTHFGRLVRRWRWTTAEDPVKVEQAVGELIERKEWTLLSHRVIFHGRRVCHARRPACGVCVLAKDCPSFGLGPTEPLLAAPLVQGPETDHLLALAGL
>NC_020559.1|WP_003899635.1|4096738_4097116_+|hypothetical-protein
MFTLLVSWLLVACVPGLLMLATLGLGRLERFLARDTVTATDVAEFLEQAEAVDVHTLARNGMPEALDYLHRRQARRITDSPPLGSGAGPRYAGPLFVTDLDSPVEPPRHGQPNPQFRTARHANHV
>NC_020559.1|WP_003419728.1|4097214_4097889_+|cAMP-activated-global-transcriptional-regulator-CRP
MDEILARAGIFQGVEPSAIAALTKQLQPVDFPRGHTVFAEGEPGDRLYIIISGKVKIGRRAPDGRENLLTIMGPSDMFGELSIFDPGPRTSSATTITEVRAVSMDRDALRSWIADRPEISEQLLRVLARRLRRTNNNLADLIFTDVPGRVAKQLLQLAQRFGTQEGGALRVTHDLTQEEIAQLVGASRETVNKALADFAHRGWIRLEGKSVLISDSERLARRAR
>NC_020559.1|WP_003419731.1|4097992_4098787_-|MBL-fold-metallo-hydrolase
MSKTAESLTHPAYGQLRAVTDTASVLLADNPGLLTLDGTNTWVLRGPLSDELVVVDPGPDDDEHLARVAALGRIALVLISHRHGDHTSGIDKLVALTGAPVRAADPQFLRRDGETLTDGEVIDVAGLTITVLATPGHTADSLSFVLDDAVLTADTVLGCGTTVIDKEDGSLADYLESLHRLRGLGRRTVLPGHGPDLLDLEAIASGYLLHRHERLEQIRAALRDLGDDATVREVVEHVYLDVDEKLWNAAEWSVQAQLDYLRTR
>NC_020559.1|WP_003419733.1|4098793_4099249_-|RidA-family-protein
MSAKARLGQLGVTLPQVAAPLAAYVPAVRTGNLVYTAGQLPLEAGKLVRTGKLGADVNPEEGKTLARICALNALAAVDSLVDLDAVTRVVKVVGFVASAPGFHGQPSVINGASDLLAEVFGDSGAHARSAVGVSELPLDAPVEVELIVEVG

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_020559_1	1.2|334218|17|NC_020559|PILER-CR	334218-334234	17	NC_020559.1	840542-840558	1	0.941
NC_020559_1	1.2|334218|17|NC_020559|PILER-CR	334218-334234	17	NC_020559.1	1188645-1188661	1	0.941
NC_020559_1	1.2|334218|17|NC_020559|PILER-CR	334218-334234	17	NC_020559.1	1211966-1211982	1	0.941
NC_020559_1	1.2|334218|17|NC_020559|PILER-CR	334218-334234	17	NC_020559.1	2416485-2416501	1	0.941
NC_020559_1	1.2|334218|17|NC_020559|PILER-CR	334218-334234	17	NC_020559.1	2792776-2792792	1	0.941
NC_020559_1	1.2|334218|17|NC_020559|PILER-CR	334218-334234	17	NC_020559.1	4018008-4018024	1	0.941
NC_020559_4	4.2|962241|56|NC_020559|PILER-CR	962241-962296	56	NC_020559.1	962369-962424	1	0.982
NC_020559_9	9.4|1626376|18|NC_020559|CRISPRCasFinder	1626376-1626393	18	NC_020559.1	1217148-1217165	1	0.944
NC_020559_9	9.4|1626376|18|NC_020559|CRISPRCasFinder	1626376-1626393	18	NC_020559.1	1611814-1611831	1	0.944
NC_020559_9	9.4|1626376|18|NC_020559|CRISPRCasFinder	1626376-1626393	18	NC_020559.1	1629522-1629539	1	0.944
NC_020559_9	9.4|1626376|18|NC_020559|CRISPRCasFinder	1626376-1626393	18	NC_020559.1	1649124-1649141	1	0.944
NC_020559_9	9.4|1626376|18|NC_020559|CRISPRCasFinder	1626376-1626393	18	NC_020559.1	1993567-1993584	1	0.944
NC_020559_9	9.4|1626376|18|NC_020559|CRISPRCasFinder	1626376-1626393	18	NC_020559.1	2052403-2052420	1	0.944
NC_020559_9	9.4|1626376|18|NC_020559|CRISPRCasFinder	1626376-1626393	18	NC_020559.1	3784380-3784397	1	0.944
NC_020559_11	11.2|2079189|18|NC_020559|CRT	2079189-2079206	18	NC_020559.1	401431-401448	1	0.944
NC_020559_11	11.2|2079189|18|NC_020559|CRT	2079189-2079206	18	NC_020559.1	609015-609032	1	0.944
NC_020559_11	11.4|2079279|18|NC_020559|CRT	2079279-2079296	18	NC_020559.1	3436457-3436474	1	0.944
NC_020559_2	2.5|367121|42|NC_020559|CRISPRCasFinder	367121-367162	42	NC_020559.1	375152-375193	2	0.952
NC_020559_2	2.6|367196|33|NC_020559|CRISPRCasFinder	367196-367228	33	NC_020559.1	373967-373999	2	0.939
NC_020559_10	10.4|2052678|20|NC_020559|CRISPRCasFinder	2052678-2052697	20	NC_020559.1	924852-924871	2	0.9
NC_020559_10	10.5|2052726|20|NC_020559|CRISPRCasFinder	2052726-2052745	20	NC_020559.1	2450422-2450441	2	0.9
NC_020559_10	10.9|2052917|20|NC_020559|CRISPRCasFinder	2052917-2052936	20	NC_020559.1	1489370-1489389	2	0.9
NC_020559_10	10.9|2052917|20|NC_020559|CRISPRCasFinder	2052917-2052936	20	NC_020559.1	1847703-1847722	2	0.9
NC_020559_10	10.9|2052917|20|NC_020559|CRISPRCasFinder	2052917-2052936	20	NC_020559.1	2079785-2079804	2	0.9
NC_020559_10	10.9|2052917|20|NC_020559|CRISPRCasFinder	2052917-2052936	20	NC_020559.1	2932221-2932240	2	0.9

1. spacer 1.2|334218|17|NC_020559|PILER-CR matches to position: 840542-840558, mismatch: 1, identity: 0.941

cgctggcgccgccgtca	CRISPR spacer
cgccggcgccgccgtca	Protospacer
***.*************

2. spacer 1.2|334218|17|NC_020559|PILER-CR matches to position: 1188645-1188661, mismatch: 1, identity: 0.941

cgctggcgccgccgtca	CRISPR spacer
cgccggcgccgccgtca	Protospacer
***.*************

3. spacer 1.2|334218|17|NC_020559|PILER-CR matches to position: 1211966-1211982, mismatch: 1, identity: 0.941

cgctggcgccgccgtca	CRISPR spacer
cgctggcgccgccgcca	Protospacer
**************.**

4. spacer 1.2|334218|17|NC_020559|PILER-CR matches to position: 2416485-2416501, mismatch: 1, identity: 0.941

cgctggcgccgccgtca	CRISPR spacer
cgccggcgccgccgtca	Protospacer
***.*************

5. spacer 1.2|334218|17|NC_020559|PILER-CR matches to position: 2792776-2792792, mismatch: 1, identity: 0.941

cgctggcgccgccgtca	CRISPR spacer
cgccggcgccgccgtca	Protospacer
***.*************

6. spacer 1.2|334218|17|NC_020559|PILER-CR matches to position: 4018008-4018024, mismatch: 1, identity: 0.941

cgctggcgccgccgtca	CRISPR spacer
cgccggcgccgccgtca	Protospacer
***.*************

7. spacer 4.2|962241|56|NC_020559|PILER-CR matches to position: 962369-962424, mismatch: 1, identity: 0.982

agctgccgggaggggttcacccagcggcgcgggcaggtcgtttacggcaagttcca	CRISPR spacer
agctgccgggaggggttcacccagcggtgcgggcaggtcgtttacggcaagttcca	Protospacer
***************************.****************************

8. spacer 9.4|1626376|18|NC_020559|CRISPRCasFinder matches to position: 1217148-1217165, mismatch: 1, identity: 0.944

gccgccattgccgaccag	CRISPR spacer
gccgccattgccgaacag	Protospacer
************** ***

9. spacer 9.4|1626376|18|NC_020559|CRISPRCasFinder matches to position: 1611814-1611831, mismatch: 1, identity: 0.944

gccgccattgccgaccag	CRISPR spacer
gccgccattgccgaacag	Protospacer
************** ***

10. spacer 9.4|1626376|18|NC_020559|CRISPRCasFinder matches to position: 1629522-1629539, mismatch: 1, identity: 0.944

gccgccattgccgaccag	CRISPR spacer
gccgccgttgccgaccag	Protospacer
******.***********

11. spacer 9.4|1626376|18|NC_020559|CRISPRCasFinder matches to position: 1649124-1649141, mismatch: 1, identity: 0.944

gccgccattgccgaccag	CRISPR spacer
gccgccattgccgatcag	Protospacer
**************.***

12. spacer 9.4|1626376|18|NC_020559|CRISPRCasFinder matches to position: 1993567-1993584, mismatch: 1, identity: 0.944

gccgccattgccgaccag	CRISPR spacer
gccgccgttgccgaccag	Protospacer
******.***********

13. spacer 9.4|1626376|18|NC_020559|CRISPRCasFinder matches to position: 2052403-2052420, mismatch: 1, identity: 0.944

gccgccattgccgaccag	CRISPR spacer
gccgccgttgccgaccag	Protospacer
******.***********

14. spacer 9.4|1626376|18|NC_020559|CRISPRCasFinder matches to position: 3784380-3784397, mismatch: 1, identity: 0.944

gccgccattgccgaccag	CRISPR spacer
gccgccatcgccgaccag	Protospacer
********.*********

15. spacer 11.2|2079189|18|NC_020559|CRT matches to position: 401431-401448, mismatch: 1, identity: 0.944

gatcagcccgacggcgtt	CRISPR spacer
gatcagcccgtcggcgtt	Protospacer
********** *******

16. spacer 11.2|2079189|18|NC_020559|CRT matches to position: 609015-609032, mismatch: 1, identity: 0.944

gatcagcccgacggcgtt	CRISPR spacer
gatcagcccgtcggcgtt	Protospacer
********** *******

17. spacer 11.4|2079279|18|NC_020559|CRT matches to position: 3436457-3436474, mismatch: 1, identity: 0.944

gatcagcgtcccgccggt	CRISPR spacer
gatcagcgtcccgctggt	Protospacer
**************.***

18. spacer 2.5|367121|42|NC_020559|CRISPRCasFinder matches to position: 375152-375193, mismatch: 2, identity: 0.952

ccggtgcccgagttgaagaacccgatgtttccgctgccggag	CRISPR spacer
ccggtgcccgagttgaacaacccgacgtttccgctgccggag	Protospacer
***************** *******.****************

19. spacer 2.6|367196|33|NC_020559|CRISPRCasFinder matches to position: 373967-373999, mismatch: 2, identity: 0.939

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
aggctgccgaacccgatctggccgctgccggtg	Protospacer
********** *************.********

20. spacer 10.4|2052678|20|NC_020559|CRISPRCasFinder matches to position: 924852-924871, mismatch: 2, identity: 0.9

cggcgcctaccagcaggccg	CRISPR spacer
cggagccgaccagcaggccg	Protospacer
*** *** ************

21. spacer 10.5|2052726|20|NC_020559|CRISPRCasFinder matches to position: 2450422-2450441, mismatch: 2, identity: 0.9

ccacgccgaagaacaacccg	CRISPR spacer
ccacgccgaaggacagcccg	Protospacer
***********.***.****

22. spacer 10.9|2052917|20|NC_020559|CRISPRCasFinder matches to position: 1489370-1489389, mismatch: 2, identity: 0.9

agagcagcccgccggccccg	CRISPR spacer
agaacagcccgccgcccccg	Protospacer
***.********** *****

23. spacer 10.9|2052917|20|NC_020559|CRISPRCasFinder matches to position: 1847703-1847722, mismatch: 2, identity: 0.9

agagcagcccgccggccccg	CRISPR spacer
agagcagcccgccgacgccg	Protospacer
**************.* ***

24. spacer 10.9|2052917|20|NC_020559|CRISPRCasFinder matches to position: 2079785-2079804, mismatch: 2, identity: 0.9

agagcagcccgccggccccg	CRISPR spacer
agagcagtccgccgaccccg	Protospacer
*******.******.*****

25. spacer 10.9|2052917|20|NC_020559|CRISPRCasFinder matches to position: 2932221-2932240, mismatch: 2, identity: 0.9

agagcagcccgccggccccg	CRISPR spacer
agagtagcccgccggcgccg	Protospacer
****.*********** ***

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_020559_10	10.1|2052522|23|NC_020559|CRISPRCasFinder	2052522-2052544	23	NZ_CP011665	Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence	120516-120538	1	0.957
NC_020559_10	10.4|2052678|20|NC_020559|CRISPRCasFinder	2052678-2052697	20	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	284061-284080	1	0.95
NC_020559_10	10.8|2052866|23|NC_020559|CRISPRCasFinder	2052866-2052888	23	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	103324-103346	1	0.957
NC_020559_10	10.1|2052522|23|NC_020559|CRISPRCasFinder	2052522-2052544	23	NC_015952	Streptomyces violaceusniger Tu 4113 plasmid pSTRVI02, complete sequence	106110-106132	2	0.913
NC_020559_10	10.1|2052522|23|NC_020559|CRISPRCasFinder	2052522-2052544	23	NZ_CP015095	Pelagibaca abyssi strain JLT2014 plasmid pPABY4, complete sequence	56664-56686	2	0.913
NC_020559_10	10.1|2052522|23|NC_020559|CRISPRCasFinder	2052522-2052544	23	NC_042034	Mycobacterium phage ChrisnMich, complete sequence	546-568	2	0.913
NC_020559_10	10.8|2052866|23|NC_020559|CRISPRCasFinder	2052866-2052888	23	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	540670-540692	2	0.913
NC_020559_10	10.8|2052866|23|NC_020559|CRISPRCasFinder	2052866-2052888	23	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	369237-369259	2	0.913
NC_020559_10	10.8|2052866|23|NC_020559|CRISPRCasFinder	2052866-2052888	23	MH271318	Gordonia phage Trine, complete genome	17530-17552	2	0.913
NC_020559_10	10.8|2052866|23|NC_020559|CRISPRCasFinder	2052866-2052888	23	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	1303776-1303798	2	0.913
NC_020559_10	10.8|2052866|23|NC_020559|CRISPRCasFinder	2052866-2052888	23	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1443839-1443861	2	0.913
NC_020559_10	10.1|2052522|23|NC_020559|CRISPRCasFinder	2052522-2052544	23	NZ_KJ599675	Micrococcus sp. A7 plasmid pLMA7, complete sequence	50995-51017	3	0.87
NC_020559_10	10.1|2052522|23|NC_020559|CRISPRCasFinder	2052522-2052544	23	NZ_CP025617	Micrococcus luteus strain SGAir0127 plasmid pSGAir0127	30292-30314	3	0.87
NC_020559_10	10.1|2052522|23|NC_020559|CRISPRCasFinder	2052522-2052544	23	NZ_CP015095	Pelagibaca abyssi strain JLT2014 plasmid pPABY4, complete sequence	92042-92064	3	0.87
NC_020559_10	10.1|2052522|23|NC_020559|CRISPRCasFinder	2052522-2052544	23	NZ_KR152226	Micrococcus sp. MG-2010-D12 plasmid pJD12, complete sequence	51885-51907	3	0.87
NC_020559_10	10.1|2052522|23|NC_020559|CRISPRCasFinder	2052522-2052544	23	NC_024972	Micrococcus sp. A1 plasmid pLMA1, complete sequence	64285-64307	3	0.87
NC_020559_11	11.5|2079318|24|NC_020559|CRT	2079318-2079341	24	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	1555522-1555545	3	0.875
NC_020559_11	11.5|2079318|24|NC_020559|CRT	2079318-2079341	24	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	1560190-1560213	3	0.875
NC_020559_2	2.1|366866|27|NC_020559|CRISPRCasFinder	366866-366892	27	NC_023591	Mycobacterium phage Adler, complete genome	61249-61275	4	0.852
NC_020559_2	2.1|366866|27|NC_020559|CRISPRCasFinder	366866-366892	27	KF981876	UNVERIFIED: Mycobacterium phage ADLER F1725, complete genome	61247-61273	4	0.852
NC_020559_2	2.7|367262|27|NC_020559|CRISPRCasFinder	367262-367288	27	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	10066-10092	4	0.852
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	460464-460490	4	0.852
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NC_016652	Rhodococcus phage REQ2, complete genome	36035-36061	4	0.852
NC_020559_9	9.5|1626421|27|NC_020559|CRISPRCasFinder	1626421-1626447	27	NZ_CP020993	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP4885 plasmid pA, complete sequence	728-754	4	0.852
NC_020559_11	11.5|2079318|24|NC_020559|CRT	2079318-2079341	24	NZ_CP028348	Novosphingobium sp. THN1 plasmid pTHN, complete sequence	680430-680453	4	0.833
NC_020559_11	11.5|2079318|24|NC_020559|CRT	2079318-2079341	24	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5913119-5913142	4	0.833
NC_020559_11	11.5|2079318|24|NC_020559|CRT	2079318-2079341	24	NZ_CP015007	Aminobacter aminovorans strain KCTC 2477 plasmid pAA02, complete sequence	143186-143209	4	0.833
NC_020559_2	2.1|366866|27|NC_020559|CRISPRCasFinder	366866-366892	27	LR794124	Vibrio phage vB_Vc_SrVc9 genome assembly, chromosome: 1	34861-34887	5	0.815
NC_020559_2	2.1|366866|27|NC_020559|CRISPRCasFinder	366866-366892	27	NC_012662	Vibrio phage VP93, complete genome	35301-35327	5	0.815
NC_020559_2	2.7|367262|27|NC_020559|CRISPRCasFinder	367262-367288	27	NZ_CP016084	Streptomyces sp. SAT1 plasmid unnamed4, complete sequence	2189-2215	5	0.815
NC_020559_2	2.7|367262|27|NC_020559|CRISPRCasFinder	367262-367288	27	MN693945	Marine virus AFVG_250M952, complete genome	34909-34935	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP020899	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence	369429-369455	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP013525	Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence	338832-338858	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP013554	Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence	363377-363403	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP015368	Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p1, complete sequence	104717-104743	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP013588	Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence	338543-338569	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP013560	Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence	340811-340837	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP013577	Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence	342690-342716	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP013549	Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence	343060-343086	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP013529	Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence	355714-355740	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP013534	Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence	343060-343086	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP013539	Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence	348335-348361	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP013545	Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence	343052-343078	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP020444	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed4, complete sequence	69464-69490	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP013565	Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence	363377-363403	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP013582	Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence	355714-355740	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP013571	Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence	342690-342716	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP044078	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed1, complete sequence	10340-10366	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP031081	Paracoccus yeei strain CCUG 32053 plasmid pYEE3, complete sequence	19365-19391	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	MN586031	Gordonia phage Gambino, complete genome	3053-3079	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	KU998236	Gordonia phage Blueberry, complete genome	3053-3079	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	MN062704	Gordonia phage JuJu, complete genome	3063-3089	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	MK501729	Gordonia phage Walrus, complete genome	3053-3079	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NC_031226	Gordonia phage BaxterFox, complete genome	2982-3008	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	MK967393	Rhodococcus phage Whack, complete genome	3063-3089	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	MT723935	Gordonia phage Azula, complete genome	3053-3079	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	KU963249	Gordonia phage Yeezy, complete genome	2982-3008	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	MH153808	Gordonia phage Petra, complete genome	3053-3079	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	MT639650	Gordonia phage Ohgeesy, complete genome	2982-3008	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	MH536818	Gordonia phage Frokostdame, complete genome	3055-3081	5	0.815
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	KX557275	Gordonia phage CarolAnn, complete genome	3052-3078	5	0.815
NC_020559_6	6.2|1094485|25|NC_020559|PILER-CR	1094485-1094509	25	NZ_CP014599	Yangia sp. CCB-MM3 plasmid unnamed3, complete sequence	272081-272105	5	0.8
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP021082	Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence	423150-423179	5	0.833
NC_020559_9	9.5|1626421|27|NC_020559|CRISPRCasFinder	1626421-1626447	27	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1038058-1038084	5	0.815
NC_020559_9	9.5|1626421|27|NC_020559|CRISPRCasFinder	1626421-1626447	27	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	758718-758744	5	0.815
NC_020559_9	9.5|1626421|27|NC_020559|CRISPRCasFinder	1626421-1626447	27	NC_019309	Pseudomonas sp. K-62 plasmid pMR68, complete sequence	15264-15290	5	0.815
NC_020559_10	10.2|2052573|29|NC_020559|CRISPRCasFinder	2052573-2052601	29	NZ_CP016765	Citrobacter freundii strain B38 plasmid pOZ182, complete sequence	4306-4334	5	0.828
NC_020559_10	10.2|2052573|29|NC_020559|CRISPRCasFinder	2052573-2052601	29	NZ_CP033380	Escherichia coli strain L73 plasmid pL73-3, complete sequence	11212-11240	5	0.828
NC_020559_10	10.2|2052573|29|NC_020559|CRISPRCasFinder	2052573-2052601	29	NZ_LT883140	Escherichia coli isolate 6666666.257727.embl plasmid II	1493-1521	5	0.828
NC_020559_10	10.2|2052573|29|NC_020559|CRISPRCasFinder	2052573-2052601	29	NZ_LT883140	Escherichia coli isolate 6666666.257727.embl plasmid II	22475-22503	5	0.828
NC_020559_10	10.2|2052573|29|NC_020559|CRISPRCasFinder	2052573-2052601	29	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	42185-42213	5	0.828
NC_020559_10	10.2|2052573|29|NC_020559|CRISPRCasFinder	2052573-2052601	29	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	51227-51255	5	0.828
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NC_010850	Rhodococcus sp. NS1 plasmid pNSL1, complete sequence	92901-92931	5	0.839
NC_020559_2	2.1|366866|27|NC_020559|CRISPRCasFinder	366866-366892	27	NZ_CP045917	Pseudomonas aeruginosa strain CF39S plasmid pCF39S, complete sequence	207335-207361	6	0.778
NC_020559_2	2.6|367196|33|NC_020559|CRISPRCasFinder	367196-367228	33	NZ_CP010410	Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence	435770-435802	6	0.818
NC_020559_2	2.7|367262|27|NC_020559|CRISPRCasFinder	367262-367288	27	NZ_CP022542	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence	32942-32968	6	0.778
NC_020559_2	2.9|367412|27|NC_020559|CRISPRCasFinder	367412-367438	27	NC_009959	Dinoroseobacter shibae DFL 12 = DSM 16493 plasmid pDSHI05, complete sequence	50750-50776	6	0.778
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_CP009112	Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence	179708-179734	6	0.778
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4846911-4846937	6	0.778
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	78863-78889	6	0.778
NC_020559_2	2.10|367472|27|NC_020559|CRISPRCasFinder	367472-367498	27	MK494099	Mycobacterium phage Typha, complete genome	33831-33857	6	0.778
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	GQ141189	Bifidobacterium phage Bbif-1, complete sequence	38062-38092	6	0.806
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_LT703507	Mycobacterium chimaera strain Mycobacterium chimaera MC045 isolate Mycobacterium chimaera plasmid 3	53321-53350	6	0.8
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP015280	Mycobacterium chimaera strain DSM 44623 plasmid unnamed 2, complete sequence	54788-54817	6	0.8
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP015273	Mycobacterium chimaera strain ZUERICH-1 plasmid unnamed 1, complete sequence	45545-45574	6	0.8
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP023153	Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_2, complete sequence	42425-42454	6	0.8
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP029333	Mycobacterium avium subsp. hominissuis strain MAC109 plasmid pMAC109a, complete sequence	48727-48756	6	0.8
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP019224	Mycobacterium chimaera strain CDC 2015-22-71 plasmid pDHQP20152271_1, complete sequence	87530-87559	6	0.8
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP045964	Mycobacterium chimaera strain AUSMDU00007395 plasmid pAUSMDU00007395_01, complete sequence	36788-36817	6	0.8
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_022654	Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence	138135-138164	6	0.8
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_016623	Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence	440020-440049	6	0.8
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP029834	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence	312043-312072	6	0.8
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_016624	Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence	33681-33710	6	0.8
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP053714	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed7, complete sequence	10204-10233	6	0.8
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_016588	Azospirillum lipoferum 4B plasmid AZO_p6, complete sequence	116004-116033	6	0.8
NC_020559_9	9.5|1626421|27|NC_020559|CRISPRCasFinder	1626421-1626447	27	NZ_AP022611	Mycolicibacterium madagascariense strain JCM 13574 plasmid pJCM13574	83362-83388	6	0.778
NC_020559_9	9.5|1626421|27|NC_020559|CRISPRCasFinder	1626421-1626447	27	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1792397-1792423	6	0.778
NC_020559_9	9.5|1626421|27|NC_020559|CRISPRCasFinder	1626421-1626447	27	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	2020892-2020918	6	0.778
NC_020559_9	9.5|1626421|27|NC_020559|CRISPRCasFinder	1626421-1626447	27	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1792533-1792559	6	0.778
NC_020559_9	9.5|1626421|27|NC_020559|CRISPRCasFinder	1626421-1626447	27	NZ_CP031193	Humibacter sp. BT305 plasmid unnamed1	54402-54428	6	0.778
NC_020559_9	9.5|1626421|27|NC_020559|CRISPRCasFinder	1626421-1626447	27	NZ_KR997898	Mycobacterium avium subsp. hominissuis strain 88Br plasmid pMA100, complete sequence	11547-11573	6	0.778
NC_020559_10	10.2|2052573|29|NC_020559|CRISPRCasFinder	2052573-2052601	29	NZ_CP016453	Sphingobium sp. RAC03 plasmid pBSY17_1, complete sequence	772532-772560	6	0.793
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NC_009478	Clavibacter michiganensis subsp. michiganensis NCPPB 382 plasmid pCM1, complete sequence	8328-8358	6	0.806
NC_020559_2	2.4|367061|27|NC_020559|CRISPRCasFinder	367061-367087	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	48081-48107	7	0.741
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	MK977708	Mycobacterium phage Fulbright, complete genome	10281-10311	7	0.774
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	MG099948	Mycobacterium phage Philonius, complete genome	10281-10311	7	0.774
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	MH926055	Mycobacterium phage Chewbacca, complete genome	10281-10311	7	0.774
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	MT723932	Mycobacterium phage Schnauzer, complete genome	10281-10311	7	0.774
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	KU935726	Mycobacterium phage Xerxes, complete genome	10281-10311	7	0.774
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	KU935730	Mycobacterium phage Pipsqueaks, complete genome	10281-10311	7	0.774
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	MH316570	Mycobacterium phage Silvafighter, complete genome	10281-10311	7	0.774
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	MK524518	Mycobacterium phage Smurph, complete genome	10281-10311	7	0.774
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	MK524515	Mycobacterium phage Parmesanjohn, complete genome	10281-10311	7	0.774
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	MH697585	Mycobacterium phage Gex, complete genome	10280-10310	7	0.774
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	KM588359	Mycobacterium phage Carcharodon, complete genome	10281-10311	7	0.774
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	MH697576	Mycobacterium phage Aggie, complete genome	10282-10312	7	0.774
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	MH697593	Mycobacterium phage Tapioca, complete genome	10281-10311	7	0.774
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	MG099936	Mycobacterium phage Andies, complete genome	10281-10311	7	0.774
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	NC_031243	Mycobacterium phage Xeno, complete genome	10281-10311	7	0.774
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	JN256079	Mycobacterium phage Charlie, complete genome	10281-10311	7	0.774
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_009427	Novosphingobium aromaticivorans DSM 12444 plasmid pNL2, complete sequence	183450-183479	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_LN832562	Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence	538685-538714	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP022369	Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence	167906-167935	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP039640	Azospirillum sp. TSH100 plasmid p1, complete sequence	183247-183276	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	330698-330727	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	322243-322272	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP029831	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence	312119-312148	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP029833	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence	114281-114310	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	933588-933617	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP011523	Streptomyces sp. CFMR 7 strain CFMR-7 plasmid unnamed, complete sequence	78149-78178	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	482450-482479	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_014718	Paraburkholderia rhizoxinica HKI 454 plasmid pBRH01, complete sequence	434374-434403	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_LR134459	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 17, complete sequence	205080-205109	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_012520	Rhodococcus opacus B4 plasmid pROB01, complete sequence	253977-254006	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP031166	Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence	492502-492531	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP020040	Streptomyces sp. 3211 isolate 3 plasmid p3211-1, complete sequence	372452-372481	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP020952	Rhizobium sp. CIAT894 plasmid pRheCIAT894e, complete sequence	136131-136160	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP039425	Citricoccus sp. SGAir0253 plasmid unnamed1, complete sequence	82830-82859	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	300776-300805	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	34566-34595	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP023549	Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence	158253-158282	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP023549	Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence	158790-158819	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	71404-71433	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP039430	Citricoccus sp. SGAir0453 plasmid unnamed1, complete sequence	82828-82857	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	802969-802998	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP053565	Pseudonocardia sp. Gen01 plasmid unnamed1, complete sequence	53518-53547	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_019407	Caulobacter phage CcrMagneto, complete genome	43002-43031	7	0.767
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_019411	Caulobacter phage CcrSwift, complete genome	42964-42993	7	0.767
NC_020559_10	10.2|2052573|29|NC_020559|CRISPRCasFinder	2052573-2052601	29	NZ_CP022999	Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-A, complete sequence	1487216-1487244	7	0.759
NC_020559_11	11.3|2079228|30|NC_020559|CRT	2079228-2079257	30	NZ_CP015065	Mesorhizobium ciceri biovar biserrulae strain WSM1284 plasmid pMc1284, complete sequence	52187-52216	7	0.767
NC_020559_11	11.3|2079228|30|NC_020559|CRT	2079228-2079257	30	NZ_CP015063	Mesorhizobium ciceri strain CC1192 plasmid pMc1192, complete sequence	75140-75169	7	0.767
NC_020559_11	11.3|2079228|30|NC_020559|CRT	2079228-2079257	30	NC_014918	Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence	376489-376518	7	0.767
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NZ_CP010990	Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence	147567-147597	7	0.774
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NZ_CP012186	Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence	36995-37025	7	0.774
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NZ_CP042263	Litoreibacter sp. LN3S51 plasmid unnamed2, complete sequence	372247-372277	7	0.774
NC_020559_2	2.6|367196|33|NC_020559|CRISPRCasFinder	367196-367228	33	NZ_CP017105	Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence	1386736-1386768	8	0.758
NC_020559_2	2.6|367196|33|NC_020559|CRISPRCasFinder	367196-367228	33	NC_016624	Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence	35126-35158	8	0.758
NC_020559_2	2.6|367196|33|NC_020559|CRISPRCasFinder	367196-367228	33	NZ_CP039965	Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence	1241611-1241643	8	0.758
NC_020559_2	2.6|367196|33|NC_020559|CRISPRCasFinder	367196-367228	33	CP007644	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence	275839-275871	8	0.758
NC_020559_2	2.6|367196|33|NC_020559|CRISPRCasFinder	367196-367228	33	NZ_CP029834	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence	310597-310629	8	0.758
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	16034-16063	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	726972-727001	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP024892	Rhodococcus ruber strain YYL plasmid pYYL1.1, complete sequence	196636-196665	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	MG793454	Mycobacterium phage SWU2, complete genome	25674-25703	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_017385	Ketogulonicigenium vulgare WSH-001 plasmid 2, complete sequence	110710-110739	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	667617-667646	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP032325	Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence	180177-180206	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP035092	Paracoccus denitrificans strain ATCC 19367 plasmid unnamed1, complete sequence	503975-504004	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP012910	Ketogulonicigenium vulgare strain Hbe602 plasmid 2, complete sequence	134276-134305	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_008688	Paracoccus denitrificans PD1222 plasmid 1, complete sequence	97508-97537	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	439946-439975	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_016110	Streptomyces pratensis ATCC 33331 plasmid pSFLA01, complete sequence	156404-156433	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP033582	Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence	182007-182036	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP032341	Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence	741945-741974	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_014626	Ketogulonicigenium vulgare Y25 plasmid pYP12, complete sequence	162125-162154	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP010016	Burkholderia thailandensis 34 plasmid unnamed, complete sequence	152781-152810	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	314112-314141	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP012916	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence	306660-306689	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	MH045568	Microbacterium phage Kieran, complete genome	33639-33668	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	MN062717	Microbacterium phage Sharkboy, complete genome	33721-33750	8	0.733
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_042099	Microbacterium phage Dismas, complete genome	33631-33660	8	0.733
NC_020559_10	10.2|2052573|29|NC_020559|CRISPRCasFinder	2052573-2052601	29	NC_014841	Pantoea sp. At-9b plasmid pPAT9B04, complete sequence	235558-235586	8	0.724
NC_020559_11	11.3|2079228|30|NC_020559|CRT	2079228-2079257	30	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	9194-9223	8	0.733
NC_020559_11	11.3|2079228|30|NC_020559|CRT	2079228-2079257	30	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	983284-983313	8	0.733
NC_020559_14	14.26|3108832|29|NC_020559|PILER-CR	3108832-3108860	29	MK599315	Pseudomonas phage PA1C, complete genome	299172-299200	8	0.724
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	CP033373	Lactobacillus fermentum strain DR9 plasmid unnamed2, complete sequence	12237-12267	8	0.742
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1260343-1260373	8	0.742
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	1009358-1009388	8	0.742
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1260501-1260531	8	0.742
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1009351-1009381	8	0.742
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	756669-756699	8	0.742
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1137767-1137797	8	0.742
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	1009365-1009395	8	0.742
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1260057-1260087	8	0.742
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1260001-1260031	8	0.742
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	981946-981976	8	0.742
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	938267-938297	8	0.742
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	748414-748444	8	0.742
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	896022-896052	8	0.742
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NZ_CP027299	Streptomyces sp. SGAir0924 plasmid unnamed_5	215713-215743	8	0.742
NC_020559_15	15.7|3724320|31|NC_020559|CRT	3724320-3724350	31	NC_014213	Meiothermus silvanus DSM 9946 plasmid pMESIL01, complete sequence	111748-111778	8	0.742
NC_020559_2	2.6|367196|33|NC_020559|CRISPRCasFinder	367196-367228	33	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	91175-91207	9	0.727
NC_020559_2	2.6|367196|33|NC_020559|CRISPRCasFinder	367196-367228	33	NZ_CP016287	Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence	668963-668995	9	0.727
NC_020559_2	2.6|367196|33|NC_020559|CRISPRCasFinder	367196-367228	33	NZ_CP022565	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence	789706-789738	9	0.727
NC_020559_2	2.6|367196|33|NC_020559|CRISPRCasFinder	367196-367228	33	NZ_CP048281	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence	625853-625885	9	0.727
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	NZ_CP014964	Geobacter anodireducens strain SD-1 plasmid pSD, complete sequence	13698-13728	9	0.71
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	NC_015974	Sphingobium sp. SYK-6 plasmid pSLPG, complete sequence	20960-20990	9	0.71
NC_020559_3	3.1|693013|31|NC_020559|CRISPRCasFinder	693013-693043	31	NZ_CP005085	Sphingobium sp. TKS plasmid pTK1, complete sequence	15390-15420	9	0.71
NC_020559_5	5.2|1090803|33|NC_020559|PILER-CR	1090803-1090835	33	NZ_CP051473	Rhodobacter sphaeroides strain CH10 plasmid pRspCH10DE, complete sequence	3784-3816	9	0.727
NC_020559_5	5.2|1090803|33|NC_020559|PILER-CR	1090803-1090835	33	NZ_CP051473	Rhodobacter sphaeroides strain CH10 plasmid pRspCH10DE, complete sequence	47587-47619	9	0.727
NC_020559_5	5.2|1090803|33|NC_020559|PILER-CR	1090803-1090835	33	NZ_CP030276	Rhodobacter sphaeroides 2.4.1 plasmid pDE, complete sequence	3783-3815	9	0.727
NC_020559_5	5.2|1090803|33|NC_020559|PILER-CR	1090803-1090835	33	NZ_CP030276	Rhodobacter sphaeroides 2.4.1 plasmid pDE, complete sequence	47594-47626	9	0.727
NC_020559_5	5.2|1090803|33|NC_020559|PILER-CR	1090803-1090835	33	CP047036	Rhodobacter sphaeroides strain DSM 158 plasmid pDx, complete sequence	18215-18247	9	0.727
NC_020559_5	5.2|1090803|33|NC_020559|PILER-CR	1090803-1090835	33	NZ_CP015289	Rhodobacter sphaeroides strain MBTLJ-20 plasmid a, complete sequence	90904-90936	9	0.727
NC_020559_5	5.2|1090803|33|NC_020559|PILER-CR	1090803-1090835	33	NZ_CP015289	Rhodobacter sphaeroides strain MBTLJ-20 plasmid a, complete sequence	134719-134751	9	0.727
NC_020559_5	5.2|1090803|33|NC_020559|PILER-CR	1090803-1090835	33	NZ_CP047042	Rhodobacter sphaeroides strain 2.4.1 substr. H2 plasmid pDx, complete sequence	18199-18231	9	0.727
NC_020559_5	5.2|1090803|33|NC_020559|PILER-CR	1090803-1090835	33	NZ_CP015212	Rhodobacter sphaeroides strain MBTLJ-13 plasmid a, complete sequence	3079-3111	9	0.727
NC_020559_5	5.2|1090803|33|NC_020559|PILER-CR	1090803-1090835	33	NZ_CP015212	Rhodobacter sphaeroides strain MBTLJ-13 plasmid a, complete sequence	46898-46930	9	0.727
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	CP054927	Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence	575921-575950	9	0.7
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	222914-222943	9	0.7
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	CP053415	Salmonella enterica strain 2011K-0868 plasmid unnamed, complete sequence	5252-5281	9	0.7
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	CP053327	Salmonella enterica subsp. salamae serovar 58:c:z6 strain 2013K-0366 plasmid unnamed, complete sequence	13606-13635	9	0.7
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP030289	Salmonella enterica subsp. enterica serovar Gaminara str. SA20063285 plasmid pIncI1.1, complete sequence	29154-29183	9	0.7
NC_020559_15	15.5|3724179|34|NC_020559|CRT	3724179-3724212	34	NZ_CP021805	Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence	922290-922323	9	0.735
NC_020559_15	15.5|3724179|34|NC_020559|CRT	3724179-3724212	34	MG812496	Gordonia phage SallySpecial, complete genome	7675-7708	9	0.735
NC_020559_2	2.6|367196|33|NC_020559|CRISPRCasFinder	367196-367228	33	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	91179-91211	10	0.697
NC_020559_2	2.6|367196|33|NC_020559|CRISPRCasFinder	367196-367228	33	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	90245-90277	10	0.697
NC_020559_2	2.6|367196|33|NC_020559|CRISPRCasFinder	367196-367228	33	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	99166-99198	10	0.697
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	NZ_CP011274	Planctomyces sp. SH-PL62 plasmid pPL62-1, complete sequence	77997-78026	10	0.667
NC_020559_13	13.9|3106506|35|NC_020559|PILER-CR,CRISPRCasFinder,CRT	3106506-3106540	35	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	414652-414686	10	0.714
NC_020559_14	14.22|3109706|34|NC_020559|CRISPRCasFinder,CRT	3109706-3109739	34	NZ_AP022335	Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49c, complete sequence	171698-171731	10	0.706
NC_020559_14	14.38|3109710|34|NC_020559|PILER-CR	3109710-3109743	34	NZ_AP022335	Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49c, complete sequence	171698-171731	10	0.706
NC_020559_15	15.5|3724179|34|NC_020559|CRT	3724179-3724212	34	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	470079-470112	10	0.706
NC_020559_15	15.5|3724179|34|NC_020559|CRT	3724179-3724212	34	NZ_CP024986	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence	68774-68807	10	0.706
NC_020559_15	15.5|3724179|34|NC_020559|CRT	3724179-3724212	34	NC_024970	Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence	172270-172303	10	0.706
NC_020559_15	15.5|3724179|34|NC_020559|CRT	3724179-3724212	34	NZ_KJ396772	Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence	172270-172303	10	0.706
NC_020559_15	15.5|3724179|34|NC_020559|CRT	3724179-3724212	34	NZ_CP029831	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence	326578-326611	11	0.676
NC_020559_7	7.1|1625779|30|NC_020559|CRISPRCasFinder	1625779-1625808	30	MK801723	Gordonia phage Coeur, complete genome	4295-4324	12	0.6

1. spacer 10.1|2052522|23|NC_020559|CRISPRCasFinder matches to NZ_CP011665 (Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence) position: , mismatch: 1, identity: 0.957

cgagcccaccggcgcccccggca	CRISPR spacer
cgagcccaccggcgcccccgaca	Protospacer
********************.**

2. spacer 10.4|2052678|20|NC_020559|CRISPRCasFinder matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 1, identity: 0.95

cggcgcctaccagcaggccg	CRISPR spacer
cggcgcctaccagcaggccc	Protospacer
******************* 

3. spacer 10.8|2052866|23|NC_020559|CRISPRCasFinder matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 1, identity: 0.957

ccaccccaccaccggcgcgtccg	CRISPR spacer
ccacaccaccaccggcgcgtccg	Protospacer
**** ******************

4. spacer 10.1|2052522|23|NC_020559|CRISPRCasFinder matches to NC_015952 (Streptomyces violaceusniger Tu 4113 plasmid pSTRVI02, complete sequence) position: , mismatch: 2, identity: 0.913

cgagcccaccggcgcccccggca	CRISPR spacer
cgagcccaccggcgccctcggcg	Protospacer
*****************.****.

5. spacer 10.1|2052522|23|NC_020559|CRISPRCasFinder matches to NZ_CP015095 (Pelagibaca abyssi strain JLT2014 plasmid pPABY4, complete sequence) position: , mismatch: 2, identity: 0.913

cgagcccaccggcgcccccggca	CRISPR spacer
cgagcccaccggcgcgcccgtca	Protospacer
*************** **** **

6. spacer 10.1|2052522|23|NC_020559|CRISPRCasFinder matches to NC_042034 (Mycobacterium phage ChrisnMich, complete sequence) position: , mismatch: 2, identity: 0.913

cgagcccaccggcgcccccggca	CRISPR spacer
cgagcccaccggtgaccccggca	Protospacer
************.* ********

7. spacer 10.8|2052866|23|NC_020559|CRISPRCasFinder matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 2, identity: 0.913

ccaccccaccaccggcgcgtccg	CRISPR spacer
ccatcccaccaccggctcgtccg	Protospacer
***.************ ******

8. spacer 10.8|2052866|23|NC_020559|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 2, identity: 0.913

ccaccccaccaccggcgcgtccg	CRISPR spacer
ccgccccaccaccggcgcttccg	Protospacer
**.*************** ****

9. spacer 10.8|2052866|23|NC_020559|CRISPRCasFinder matches to MH271318 (Gordonia phage Trine, complete genome) position: , mismatch: 2, identity: 0.913

ccaccccaccaccggcgcgtccg	CRISPR spacer
ccaccccaccaccggcgctttcg	Protospacer
****************** *.**

10. spacer 10.8|2052866|23|NC_020559|CRISPRCasFinder matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 2, identity: 0.913

ccaccccaccaccggcgcgtccg	CRISPR spacer
ccaccccaccaccggcgagtacg	Protospacer
***************** ** **

11. spacer 10.8|2052866|23|NC_020559|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 2, identity: 0.913

ccaccccaccaccggcgcgtccg	CRISPR spacer
ccgccccaccaccggcgcttccg	Protospacer
**.*************** ****

12. spacer 10.1|2052522|23|NC_020559|CRISPRCasFinder matches to NZ_KJ599675 (Micrococcus sp. A7 plasmid pLMA7, complete sequence) position: , mismatch: 3, identity: 0.87

cgagcccaccggcgcccccggca	CRISPR spacer
gcagcccaccagcgcccccggca	Protospacer
  ********.************

13. spacer 10.1|2052522|23|NC_020559|CRISPRCasFinder matches to NZ_CP025617 (Micrococcus luteus strain SGAir0127 plasmid pSGAir0127) position: , mismatch: 3, identity: 0.87

cgagcccaccggcgcccccggca	CRISPR spacer
gcagcccaccagcgcccccggca	Protospacer
  ********.************

14. spacer 10.1|2052522|23|NC_020559|CRISPRCasFinder matches to NZ_CP015095 (Pelagibaca abyssi strain JLT2014 plasmid pPABY4, complete sequence) position: , mismatch: 3, identity: 0.87

cgagcccaccggcgcccccggca	CRISPR spacer
cattcccaccggcgcccccggca	Protospacer
*.  *******************

15. spacer 10.1|2052522|23|NC_020559|CRISPRCasFinder matches to NZ_KR152226 (Micrococcus sp. MG-2010-D12 plasmid pJD12, complete sequence) position: , mismatch: 3, identity: 0.87

cgagcccaccggcgcccccggca	CRISPR spacer
gcagcccaccagcgcccccggca	Protospacer
  ********.************

16. spacer 10.1|2052522|23|NC_020559|CRISPRCasFinder matches to NC_024972 (Micrococcus sp. A1 plasmid pLMA1, complete sequence) position: , mismatch: 3, identity: 0.87

cgagcccaccggcgcccccggca	CRISPR spacer
gcagcccaccagcgcccccggca	Protospacer
  ********.************

17. spacer 11.5|2079318|24|NC_020559|CRT matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 3, identity: 0.875

atcgaagaagctgaacccgccgtt	CRISPR spacer
cgcgaagaagctgaagccgccgtt	Protospacer
  ************* ********

18. spacer 11.5|2079318|24|NC_020559|CRT matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 3, identity: 0.875

atcgaagaagctgaacccgccgtt	CRISPR spacer
cgcgaagaagctgaagccgccgtt	Protospacer
  ************* ********

19. spacer 2.1|366866|27|NC_020559|CRISPRCasFinder matches to NC_023591 (Mycobacterium phage Adler, complete genome) position: , mismatch: 4, identity: 0.852

-aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
cagtgc-ccggtgtccccatcgcccgtg	Protospacer
 *..** ********* ***********

20. spacer 2.1|366866|27|NC_020559|CRISPRCasFinder matches to KF981876 (UNVERIFIED: Mycobacterium phage ADLER F1725, complete genome) position: , mismatch: 4, identity: 0.852

-aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
cagtgc-ccggtgtccccatcgcccgtg	Protospacer
 *..** ********* ***********

21. spacer 2.7|367262|27|NC_020559|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 4, identity: 0.852

gcgaagccgatgttgtagctgccggtg	CRISPR spacer
ccgaagccgatgtcgtagcggccggcg	Protospacer
 ************.***** *****.*

22. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.852

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgaaggtgaggtcgccgggg	Protospacer
.* ********* ***********.**

23. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NC_016652 (Rhodococcus phage REQ2, complete genome) position: , mismatch: 4, identity: 0.852

accccgccgaagttgaggtcgccgagg	CRISPR spacer
acggcgccgaagttgaggccgccgacg	Protospacer
**  **************.****** *

24. spacer 9.5|1626421|27|NC_020559|CRISPRCasFinder matches to NZ_CP020993 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP4885 plasmid pA, complete sequence) position: , mismatch: 4, identity: 0.852

gccggccagccagccaccccgcccccc	CRISPR spacer
gccagccagccacccaccccgccgcac	Protospacer
***.******** ********** * *

25. spacer 11.5|2079318|24|NC_020559|CRT matches to NZ_CP028348 (Novosphingobium sp. THN1 plasmid pTHN, complete sequence) position: , mismatch: 4, identity: 0.833

atcgaagaagctgaacccgccgtt	CRISPR spacer
atcgaagaagctgaacacgcccgc	Protospacer
**************** ****  .

26. spacer 11.5|2079318|24|NC_020559|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 4, identity: 0.833

atcgaagaagctgaacccgccgtt	CRISPR spacer
gtcgatgaagctgaacccgccgaa	Protospacer
.**** ****************  

27. spacer 11.5|2079318|24|NC_020559|CRT matches to NZ_CP015007 (Aminobacter aminovorans strain KCTC 2477 plasmid pAA02, complete sequence) position: , mismatch: 4, identity: 0.833

atcgaagaagctgaacccgccgtt	CRISPR spacer
atcggagaagctgaacccgcccgg	Protospacer
****.****************   

28. spacer 2.1|366866|27|NC_020559|CRISPRCasFinder matches to LR794124 (Vibrio phage vB_Vc_SrVc9 genome assembly, chromosome: 1) position: , mismatch: 5, identity: 0.815

aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
aacgcaccgttgtccacatcaccaatc	Protospacer
********* **********.** .* 

29. spacer 2.1|366866|27|NC_020559|CRISPRCasFinder matches to NC_012662 (Vibrio phage VP93, complete genome) position: , mismatch: 5, identity: 0.815

aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
aacgcaccgttgtccacatcaccaatc	Protospacer
********* **********.** .* 

30. spacer 2.7|367262|27|NC_020559|CRISPRCasFinder matches to NZ_CP016084 (Streptomyces sp. SAT1 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.815

gcgaagccgatgttgtagctgccggtg	CRISPR spacer
gcgaagccgaagttgtagctgcgctcg	Protospacer
********** ***********   .*

31. spacer 2.7|367262|27|NC_020559|CRISPRCasFinder matches to MN693945 (Marine virus AFVG_250M952, complete genome) position: , mismatch: 5, identity: 0.815

gcgaagccgatgttgtagctgccggtg	CRISPR spacer
atgaagccgatgttgtcgctaccgggg	Protospacer
..************** ***.**** *

32. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP020899 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

33. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP013525 (Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

34. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP013554 (Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

35. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP015368 (Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p1, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tccccgcggaagttgaggtcgcgggtg	Protospacer
 ****** ************** *. *

36. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP013588 (Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

37. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP013560 (Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

38. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP013577 (Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

39. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP013549 (Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

40. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP013529 (Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

41. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP013534 (Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

42. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP013539 (Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

43. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP013545 (Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

44. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP020444 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcaccgccgaagttgaagtggccgagc	Protospacer
 * *************.** ****** 

45. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP013565 (Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

46. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP013582 (Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

47. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP013571 (Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

48. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP044078 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcaccgccgaagttgaagtggccgagc	Protospacer
 * *************.** ****** 

49. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP031081 (Paracoccus yeei strain CCUG 32053 plasmid pYEE3, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcaccgccgaagttgaagtggccgagc	Protospacer
 * *************.** ****** 

50. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to MN586031 (Gordonia phage Gambino, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

51. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to KU998236 (Gordonia phage Blueberry, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

52. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to MN062704 (Gordonia phage JuJu, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

53. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to MK501729 (Gordonia phage Walrus, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

54. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NC_031226 (Gordonia phage BaxterFox, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

55. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to MK967393 (Rhodococcus phage Whack, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tccttaccgaagttgaggtcgacgagg	Protospacer
 **...*************** *****

56. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to MT723935 (Gordonia phage Azula, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

57. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to KU963249 (Gordonia phage Yeezy, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

58. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to MH153808 (Gordonia phage Petra, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

59. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to MT639650 (Gordonia phage Ohgeesy, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

60. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to MH536818 (Gordonia phage Frokostdame, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

61. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to KX557275 (Gordonia phage CarolAnn, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

62. spacer 6.2|1094485|25|NC_020559|PILER-CR matches to NZ_CP014599 (Yangia sp. CCB-MM3 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.8

atccgccaccccgcttggaccgttg	CRISPR spacer
ccccgacaccccgcttggaccgtaa	Protospacer
 .*** ***************** .

63. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP021082 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence) position: , mismatch: 5, identity: 0.833

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cgcgccggccaccccggcgacggtggtctt	Protospacer
* ******** * *************. **

64. spacer 9.5|1626421|27|NC_020559|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 5, identity: 0.815

gccggccagccagccaccccgcccccc	CRISPR spacer
ccgagccagcccgccaccccgcccgcc	Protospacer
 * .******* ************ **

65. spacer 9.5|1626421|27|NC_020559|CRISPRCasFinder matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.815

gccggccagccagccaccccgcccccc	CRISPR spacer
cccggtccgccagccaccccgcccaca	Protospacer
 ****.* **************** * 

66. spacer 9.5|1626421|27|NC_020559|CRISPRCasFinder matches to NC_019309 (Pseudomonas sp. K-62 plasmid pMR68, complete sequence) position: , mismatch: 5, identity: 0.815

gccggccagccagccaccccgcccccc	CRISPR spacer
gccggccagccagcaacgccgcctgct	Protospacer
************** ** *****. *.

67. spacer 10.2|2052573|29|NC_020559|CRISPRCasFinder matches to NZ_CP016765 (Citrobacter freundii strain B38 plasmid pOZ182, complete sequence) position: , mismatch: 5, identity: 0.828

cggcgccgccggcaccaaacagcaggccc	CRISPR spacer
gaacgccgccagcaccaaacagcagaccc	Protospacer
 ..*******.**************.***

68. spacer 10.2|2052573|29|NC_020559|CRISPRCasFinder matches to NZ_CP033380 (Escherichia coli strain L73 plasmid pL73-3, complete sequence) position: , mismatch: 5, identity: 0.828

cggcgccgccggcaccaaacagcaggccc	CRISPR spacer
gaacgccgccagcaccaaacagcagcccc	Protospacer
 ..*******.************** ***

69. spacer 10.2|2052573|29|NC_020559|CRISPRCasFinder matches to NZ_LT883140 (Escherichia coli isolate 6666666.257727.embl plasmid II) position: , mismatch: 5, identity: 0.828

cggcgccgccggcaccaaacagcaggccc	CRISPR spacer
gaacgccgccagcaccaaacagcagcccc	Protospacer
 ..*******.************** ***

70. spacer 10.2|2052573|29|NC_020559|CRISPRCasFinder matches to NZ_LT883140 (Escherichia coli isolate 6666666.257727.embl plasmid II) position: , mismatch: 5, identity: 0.828

cggcgccgccggcaccaaacagcaggccc	CRISPR spacer
gaacgccgccagcaccaaacagcagcccc	Protospacer
 ..*******.************** ***

71. spacer 10.2|2052573|29|NC_020559|CRISPRCasFinder matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 5, identity: 0.828

cggcgccgccggcaccaaacagcaggccc	CRISPR spacer
cgacagcgccggcaccagccagcaggccc	Protospacer
**.*. ***********. **********

72. spacer 10.2|2052573|29|NC_020559|CRISPRCasFinder matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 5, identity: 0.828

cggcgccgccggcaccaaacagcaggccc	CRISPR spacer
cgacagcgccggcaccagccagcaggccc	Protospacer
**.*. ***********. **********

73. spacer 15.7|3724320|31|NC_020559|CRT matches to NC_010850 (Rhodococcus sp. NS1 plasmid pNSL1, complete sequence) position: , mismatch: 5, identity: 0.839

aacgccc-acttcaccgccgttgccgccgtca	CRISPR spacer
-acacccgacttcaccgccgctgccgccgaga	Protospacer
 **.*** ************.********  *

74. spacer 2.1|366866|27|NC_020559|CRISPRCasFinder matches to NZ_CP045917 (Pseudomonas aeruginosa strain CF39S plasmid pCF39S, complete sequence) position: , mismatch: 6, identity: 0.778

aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
agttcactggtgtccacatcgcccgaa	Protospacer
*.. ***.***************** .

75. spacer 2.6|367196|33|NC_020559|CRISPRCasFinder matches to NZ_CP010410 (Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.818

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
agcaggtcgatcacgatctggccgttgccggcg	Protospacer
**   *.***** ******************.*

76. spacer 2.7|367262|27|NC_020559|CRISPRCasFinder matches to NZ_CP022542 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence) position: , mismatch: 6, identity: 0.778

gcgaagccgatgttgtagctgccggtg	CRISPR spacer
ggataggcgatgttgtagctgccggaa	Protospacer
* . ** ****************** .

77. spacer 2.9|367412|27|NC_020559|CRISPRCasFinder matches to NC_009959 (Dinoroseobacter shibae DFL 12 = DSM 16493 plasmid pDSHI05, complete sequence) position: , mismatch: 6, identity: 0.778

gccaagccgatatcgaagatcccggtg	CRISPR spacer
accatgccgatatcgacgatcccgtcc	Protospacer
.*** *********** ******* . 

78. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_CP009112 (Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence) position: , mismatch: 6, identity: 0.778

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tagacgccgaagtcgaggtcggcgagg	Protospacer
    *********.******* *****

79. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.778

accccgccgaagttgaggtcgccgagg	CRISPR spacer
ctcccgccgaagttgagggtgccgaac	Protospacer
 .**************** .*****. 

80. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 6, identity: 0.778

accccgccgaagttgaggtcgccgagg	CRISPR spacer
aagaagccgaagttgaggtcgccgtag	Protospacer
*    ******************* .*

81. spacer 2.10|367472|27|NC_020559|CRISPRCasFinder matches to MK494099 (Mycobacterium phage Typha, complete genome) position: , mismatch: 6, identity: 0.778

accccgccgaagttgaggtcgccgagg	CRISPR spacer
cggtcgccgaggtcgaggtcgccgagg	Protospacer
   .******.**.*************

82. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to GQ141189 (Bifidobacterium phage Bbif-1, complete sequence) position: , mismatch: 6, identity: 0.806

agcgcgaacggcaagccgaac----cgttggaccc	CRISPR spacer
agcgcgaacggccagccgaaccatgcgctgg----	Protospacer
************ ********    **.***    

83. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_LT703507 (Mycobacterium chimaera strain Mycobacterium chimaera MC045 isolate Mycobacterium chimaera plasmid 3) position: , mismatch: 6, identity: 0.8

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gatgccggccgcgccgccgacggtggcgat	Protospacer
  .******* ***** *********** *

84. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP015280 (Mycobacterium chimaera strain DSM 44623 plasmid unnamed 2, complete sequence) position: , mismatch: 6, identity: 0.8

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gatgccggccgcgccgccgacggtggcgat	Protospacer
  .******* ***** *********** *

85. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP015273 (Mycobacterium chimaera strain ZUERICH-1 plasmid unnamed 1, complete sequence) position: , mismatch: 6, identity: 0.8

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gatgccggccgcgccgccgacggtggcgat	Protospacer
  .******* ***** *********** *

86. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP023153 (Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_2, complete sequence) position: , mismatch: 6, identity: 0.8

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gatgccggccgcgccgccgacggtggcgat	Protospacer
  .******* ***** *********** *

87. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP029333 (Mycobacterium avium subsp. hominissuis strain MAC109 plasmid pMAC109a, complete sequence) position: , mismatch: 6, identity: 0.8

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gatgccggccgcgccgccgacggtggcgat	Protospacer
  .******* ***** *********** *

88. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP019224 (Mycobacterium chimaera strain CDC 2015-22-71 plasmid pDHQP20152271_1, complete sequence) position: , mismatch: 6, identity: 0.8

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gatgccggccgcgccgccgacggtggcgat	Protospacer
  .******* ***** *********** *

89. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP045964 (Mycobacterium chimaera strain AUSMDU00007395 plasmid pAUSMDU00007395_01, complete sequence) position: , mismatch: 6, identity: 0.8

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gatgccggccgcgccgccgacggtggcgat	Protospacer
  .******* ***** *********** *

90. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_022654 (Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence) position: , mismatch: 6, identity: 0.8

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gatgccggccgcgccgccgacggtggcgat	Protospacer
  .******* ***** *********** *

91. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_016623 (Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence) position: , mismatch: 6, identity: 0.8

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cccgccggccccggcggcgaccgttcccgt	Protospacer
************* ******* **  *  *

92. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP029834 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.8

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cgggccggccacgccggcgacgggggtggt	Protospacer
*  ******* ************ **.* *

93. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_016624 (Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence) position: , mismatch: 6, identity: 0.8

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cgggccggccacgccggcgacgggggtggt	Protospacer
*  ******* ************ **.* *

94. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP053714 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed7, complete sequence) position: , mismatch: 6, identity: 0.8

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gccgccggccccgccggcgccgccgccggt	Protospacer
 ****************** ** .* ** *

95. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_016588 (Azospirillum lipoferum 4B plasmid AZO_p6, complete sequence) position: , mismatch: 6, identity: 0.8

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gccgccggccccggcggtgacggtcttgtt	Protospacer
 ************ ***.******  .***

96. spacer 9.5|1626421|27|NC_020559|CRISPRCasFinder matches to NZ_AP022611 (Mycolicibacterium madagascariense strain JCM 13574 plasmid pJCM13574) position: , mismatch: 6, identity: 0.778

gccggccagccagccaccccgcccccc	CRISPR spacer
accggccagccaggcaccccgccgttg	Protospacer
.************ ********* .. 

97. spacer 9.5|1626421|27|NC_020559|CRISPRCasFinder matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

gccggccagccagccaccccgcccccc	CRISPR spacer
gccggccagccagccacgccgggagcg	Protospacer
***************** ***    * 

98. spacer 9.5|1626421|27|NC_020559|CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 6, identity: 0.778

gccggccagccagccaccccgcccccc	CRISPR spacer
gccggccagccagccacgccgggagcg	Protospacer
***************** ***    * 

99. spacer 9.5|1626421|27|NC_020559|CRISPRCasFinder matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

gccggccagccagccaccccgcccccc	CRISPR spacer
gccggccagccagccacgccgggagcg	Protospacer
***************** ***    * 

100. spacer 9.5|1626421|27|NC_020559|CRISPRCasFinder matches to NZ_CP031193 (Humibacter sp. BT305 plasmid unnamed1) position: , mismatch: 6, identity: 0.778

gccggccagccagccaccccgcccccc	CRISPR spacer
ccgcgccagccagccaccccgccgaca	Protospacer
 *  *******************  * 

101. spacer 9.5|1626421|27|NC_020559|CRISPRCasFinder matches to NZ_KR997898 (Mycobacterium avium subsp. hominissuis strain 88Br plasmid pMA100, complete sequence) position: , mismatch: 6, identity: 0.778

gccggccagccagccaccccgcccccc	CRISPR spacer
gccggccagccatccaccccgatcgag	Protospacer
************ ******** .*   

102. spacer 10.2|2052573|29|NC_020559|CRISPRCasFinder matches to NZ_CP016453 (Sphingobium sp. RAC03 plasmid pBSY17_1, complete sequence) position: , mismatch: 6, identity: 0.793

cggcgccgccggcaccaaacagcaggccc	CRISPR spacer
ccacaccgctggcaccaagcagcaggccg	Protospacer
* .*.****.********.********* 

103. spacer 15.7|3724320|31|NC_020559|CRT matches to NC_009478 (Clavibacter michiganensis subsp. michiganensis NCPPB 382 plasmid pCM1, complete sequence) position: , mismatch: 6, identity: 0.806

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgaccacttcaccgccgtcgccgccggcg	Protospacer
. ** ***************.******* *.

104. spacer 2.4|367061|27|NC_020559|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 7, identity: 0.741

aagccgcccgagttcgcgagaccgaag	CRISPR spacer
tgaccgcccgagttcgcgagacgttgg	Protospacer
 ..*******************   .*

105. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to MK977708 (Mycobacterium phage Fulbright, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

106. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to MG099948 (Mycobacterium phage Philonius, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

107. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to MH926055 (Mycobacterium phage Chewbacca, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

108. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to MT723932 (Mycobacterium phage Schnauzer, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

109. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to KU935726 (Mycobacterium phage Xerxes, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

110. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to KU935730 (Mycobacterium phage Pipsqueaks, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

111. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to MH316570 (Mycobacterium phage Silvafighter, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

112. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to MK524518 (Mycobacterium phage Smurph, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

113. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to MK524515 (Mycobacterium phage Parmesanjohn, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

114. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to MH697585 (Mycobacterium phage Gex, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

115. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to KM588359 (Mycobacterium phage Carcharodon, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

116. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to MH697576 (Mycobacterium phage Aggie, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

117. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to MH697593 (Mycobacterium phage Tapioca, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

118. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to MG099936 (Mycobacterium phage Andies, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

119. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to NC_031243 (Mycobacterium phage Xeno, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

120. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to JN256079 (Mycobacterium phage Charlie, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

121. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_009427 (Novosphingobium aromaticivorans DSM 12444 plasmid pNL2, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cgagccggccccgccggccacggtggaaaa	Protospacer
*  *************** ******* .  

122. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_LN832562 (Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
ccagccggccccgcccgcgacggcgaccaa	Protospacer
** ************ *******.*.*   

123. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP022369 (Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
ggcggcggccccggcggcgacggtggagcg	Protospacer
  ** ******** ************ *. 

124. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP039640 (Azospirillum sp. TSH100 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gaagccggccccgccggcgaccgtgccgaa	Protospacer
   ****************** *** **  

125. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
acgagcggcccctccggcgacggcggcgtg	Protospacer
 * . ******* **********.***** 

126. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cgcgtgggcgccgccggcgacggtggccgc	Protospacer
* **. *** *****************  .

127. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP029831 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cccgccggccccggcggcgaccgtccccgc	Protospacer
************* ******* **  *  .

128. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP029833 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cagcccggccccggcggcgacggtgtcggc	Protospacer
*   ********* *********** ** .

129. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 7, identity: 0.767

-cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gttcatc-gccccgccggtggcggtggcgtt	Protospacer
 ..*..* **********.*.**********

130. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP011523 (Streptomyces sp. CFMR 7 strain CFMR-7 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gaggtcggccccgccggcggcggtgtcgta	Protospacer
   *.**************.***** *** 

131. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gccggcggccccgccggcgacggcgcctgc	Protospacer
 *** ******************.* *  .

132. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_014718 (Paraburkholderia rhizoxinica HKI 454 plasmid pBRH01, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
tgcagcagccccgccggcgacgccggcgtt	Protospacer
. *. *.*************** .******

133. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_LR134459 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 17, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cgccgcggccccgccgacgacggtcgcgcg	Protospacer
* *  ***********.******* ***. 

134. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_012520 (Rhodococcus opacus B4 plasmid pROB01, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cgtcccggcggcgccggcgacggtggccct	Protospacer
* . *****  **************** .*

135. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP031166 (Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gtcgcactacccgtcggcgacggtggcgtt	Protospacer
 .***    ****.****************

136. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP020040 (Streptomyces sp. 3211 isolate 3 plasmid p3211-1, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gcccatggcgacgccggcgacggtggcgtg	Protospacer
 **  .***  ****************** 

137. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP020952 (Rhizobium sp. CIAT894 plasmid pRheCIAT894e, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cgtgccggccccgccgtcgacggtcaggat	Protospacer
* .************* ******* . * *

138. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP039425 (Citricoccus sp. SGAir0253 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gaccgcggcgccgccggccacggtggcggt	Protospacer
  *  **** ******** ********* *

139. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cccgccggcccagccggcgccggccgaggc	Protospacer
*********** ******* ***. * * .

140. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gccgccggccccgacggcgccggtctggtc	Protospacer
 ************ ***** ****   **.

141. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP023549 (Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cgtgccggccgcgccggtgacggtggtcgt	Protospacer
* .******* ******.********.  *

142. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP023549 (Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cgtgccggccgcgccggtgacggtggtcgt	Protospacer
* .******* ******.********.  *

143. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gctgccggcccgcccggcgacggtggggcc	Protospacer
 *.********  ************* *..

144. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP039430 (Citricoccus sp. SGAir0453 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gaccgcggcgccgccggccacggtggcggt	Protospacer
  *  **** ******** ********* *

145. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cgccgcggcccccgcggcgacggtggcgcc	Protospacer
* *  *******  **************..

146. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP053565 (Pseudonocardia sp. Gen01 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cagggcggcaccgacggcgacggtggcgag	Protospacer
*  * **** *** **************  

147. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_019407 (Caulobacter phage CcrMagneto, complete genome) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cccgccggccccggccgcgacgggcgaggg	Protospacer
************* * *******  * *  

148. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_019411 (Caulobacter phage CcrSwift, complete genome) position: , mismatch: 7, identity: 0.767

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cccgccggccccggccgcgacgggcgaggg	Protospacer
************* * *******  * *  

149. spacer 10.2|2052573|29|NC_020559|CRISPRCasFinder matches to NZ_CP022999 (Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-A, complete sequence) position: , mismatch: 7, identity: 0.759

cggcgccgccggcaccaaacagcaggccc	CRISPR spacer
cggcgccggcggcacccaacagcaactga	Protospacer
******** ******* *******. .  

150. spacer 11.3|2079228|30|NC_020559|CRT matches to NZ_CP015065 (Mesorhizobium ciceri biovar biserrulae strain WSM1284 plasmid pMc1284, complete sequence) position: , mismatch: 7, identity: 0.767

tcggagaaagccgtcggtttgcacgctgtt	CRISPR spacer
ttcggtaaagccgtcggtgtgcacgctgac	Protospacer
*. *. ************ ********* .

151. spacer 11.3|2079228|30|NC_020559|CRT matches to NZ_CP015063 (Mesorhizobium ciceri strain CC1192 plasmid pMc1192, complete sequence) position: , mismatch: 7, identity: 0.767

tcggagaaagccgtcggtttgcacgctgtt	CRISPR spacer
ttcggtaaagccgtcggtgtgcacgctgac	Protospacer
*. *. ************ ********* .

152. spacer 11.3|2079228|30|NC_020559|CRT matches to NC_014918 (Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence) position: , mismatch: 7, identity: 0.767

tcggagaaagccgtcggtttgcacgctgtt	CRISPR spacer
ttcggtaaagccgtcggtgtgcacgctgac	Protospacer
*. *. ************ ********* .

153. spacer 15.7|3724320|31|NC_020559|CRT matches to NZ_CP010990 (Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence) position: , mismatch: 7, identity: 0.774

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
cccacccacttcaccgacgtcgccgccgacg	Protospacer
  *.************ ***.******* *.

154. spacer 15.7|3724320|31|NC_020559|CRT matches to NZ_CP012186 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence) position: , mismatch: 7, identity: 0.774

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
cccacccacttcaccgacgtcgccgccgacg	Protospacer
  *.************ ***.******* *.

155. spacer 15.7|3724320|31|NC_020559|CRT matches to NZ_CP042263 (Litoreibacter sp. LN3S51 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.774

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
atccgccatttcaccgccgttgccgacgccg	Protospacer
* *  ***.**************** **.*.

156. spacer 2.6|367196|33|NC_020559|CRISPRCasFinder matches to NZ_CP017105 (Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttggtgtcgatctcgatctggccgttgcccgca	Protospacer
  * **.*****.**************** *..

157. spacer 2.6|367196|33|NC_020559|CRISPRCasFinder matches to NC_016624 (Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
agctggttgatgccgatctggccgctgccggtc	Protospacer
** . *..*** ************.******* 

158. spacer 2.6|367196|33|NC_020559|CRISPRCasFinder matches to NZ_CP039965 (Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
atgctgccgaccccgatctggtcgttttcgact	Protospacer
* ********.**********.**** .**.. 

159. spacer 2.6|367196|33|NC_020559|CRISPRCasFinder matches to CP007644 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
cggctgccgatcccgatcaggacgtcgaccttc	Protospacer
 ***************** ** ***.* *  * 

160. spacer 2.6|367196|33|NC_020559|CRISPRCasFinder matches to NZ_CP029834 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
agctggttgatgccgatctggccgctgccggtc	Protospacer
** . *..*** ************.******* 

161. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gccgccggccccgccggtgacgaggaagac	Protospacer
 ****************.****. *. * .

162. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gccgccggccccgccggtgacgaggaagac	Protospacer
 ****************.****. *. * .

163. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP024892 (Rhodococcus ruber strain YYL plasmid pYYL1.1, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gccgccggccccgccgtcggcggtgctcgg	Protospacer
 *************** **.***** .   

164. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to MG793454 (Mycobacterium phage SWU2, complete genome) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
accgccgtccccgccagcgacggtgatacc	Protospacer
 ****** *******.*********.....

165. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_017385 (Ketogulonicigenium vulgare WSH-001 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cgtctcggccccgccggcggcggtgacgaa	Protospacer
* . .**************.*****.**  

166. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
ggtggcggccccgctggcgacggtggacgt	Protospacer
  .* *********.***********   *

167. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP032325 (Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gccgccggccccgccggtgacgaggaagac	Protospacer
 ****************.****. *. * .

168. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP035092 (Paracoccus denitrificans strain ATCC 19367 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cgagcccgccccgcccgcgacggtggaaaa	Protospacer
*  *** ******** ********** .  

169. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP012910 (Ketogulonicigenium vulgare strain Hbe602 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cgtctcggccccgccggcggcggtgacgaa	Protospacer
* . .**************.*****.**  

170. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_008688 (Paracoccus denitrificans PD1222 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cgagcccgccccgcccgcgacggtggaaaa	Protospacer
*  *** ******** ********** .  

171. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
ggtggcggccccgctggcgacggtggacgt	Protospacer
  .* *********.***********   *

172. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_016110 (Streptomyces pratensis ATCC 33331 plasmid pSFLA01, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt-	CRISPR spacer
ccggccggccccgccggcgac-ccgacaccc	Protospacer
** ******************  .*.*... 

173. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP033582 (Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cccgccggccccgccggccatggcccgctc	Protospacer
****************** *.**.    *.

174. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP032341 (Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
ggtggcggccccgctggcgacggtggacgt	Protospacer
  .* *********.***********   *

175. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_014626 (Ketogulonicigenium vulgare Y25 plasmid pYP12, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cgtctcggccccgccggcggcggtgacgaa	Protospacer
* . .**************.*****.**  

176. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP010016 (Burkholderia thailandensis 34 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cccgccggccccgcccgcgccggcgtttgc	Protospacer
*************** *** ***.* .  .

177. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
ggtggcggccccgctggcgacggtggacgt	Protospacer
  .* *********.***********   *

178. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP012916 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
ggtggcggccccgctggcgacggtggacgt	Protospacer
  .* *********.***********   *

179. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to MH045568 (Microbacterium phage Kieran, complete genome) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cttcagggcctcgccggcgacggtggccgt	Protospacer
*..   ****.****************  *

180. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to MN062717 (Microbacterium phage Sharkboy, complete genome) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cttcagggcctcgccggcgacggtggccgt	Protospacer
*..   ****.****************  *

181. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_042099 (Microbacterium phage Dismas, complete genome) position: , mismatch: 8, identity: 0.733

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cttcagggcctcgccggcgacggtggccgt	Protospacer
*..   ****.****************  *

182. spacer 10.2|2052573|29|NC_020559|CRISPRCasFinder matches to NC_014841 (Pantoea sp. At-9b plasmid pPAT9B04, complete sequence) position: , mismatch: 8, identity: 0.724

cggcgccgccggcaccaaacagcaggccc	CRISPR spacer
tggcgccgccgggaccaaacagatacgtc	Protospacer
.*********** *********  .  .*

183. spacer 11.3|2079228|30|NC_020559|CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 8, identity: 0.733

tcggagaaagccgtcggtttgcacgctgtt	CRISPR spacer
ccgcgagcagccgtcggtttgcgcgctgtc	Protospacer
.** ... **************.******.

184. spacer 11.3|2079228|30|NC_020559|CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 8, identity: 0.733

tcggagaaagccgtcggtttgcacgctgtt	CRISPR spacer
ccgcgagcagccgtcggtttgcgcgctgtc	Protospacer
.** ... **************.******.

185. spacer 14.26|3108832|29|NC_020559|PILER-CR matches to MK599315 (Pseudomonas phage PA1C, complete genome) position: , mismatch: 8, identity: 0.724

tccgcgaaattcactgcgcgttattcaag	CRISPR spacer
gacgcgaaatacactgcgctttattttca	Protospacer
  ******** ******** *****.  .

186. spacer 15.7|3724320|31|NC_020559|CRT matches to CP033373 (Lactobacillus fermentum strain DR9 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
ttagcccacttcacggccgttgccgacgcgg	Protospacer
   *********** ********** **. .

187. spacer 15.7|3724320|31|NC_020559|CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

188. spacer 15.7|3724320|31|NC_020559|CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

189. spacer 15.7|3724320|31|NC_020559|CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

190. spacer 15.7|3724320|31|NC_020559|CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

191. spacer 15.7|3724320|31|NC_020559|CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

192. spacer 15.7|3724320|31|NC_020559|CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

193. spacer 15.7|3724320|31|NC_020559|CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

194. spacer 15.7|3724320|31|NC_020559|CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

195. spacer 15.7|3724320|31|NC_020559|CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

196. spacer 15.7|3724320|31|NC_020559|CRT matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
cgcaactccttcaccgccgctgccgccgtct	Protospacer
 .*. *. ***********.********** 

197. spacer 15.7|3724320|31|NC_020559|CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

198. spacer 15.7|3724320|31|NC_020559|CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

199. spacer 15.7|3724320|31|NC_020559|CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

200. spacer 15.7|3724320|31|NC_020559|CRT matches to NZ_CP027299 (Streptomyces sp. SGAir0924 plasmid unnamed_5) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
ctcggtggcttcgccgccgtcgccgccgtca	Protospacer
  ** . .****.*******.**********

201. spacer 15.7|3724320|31|NC_020559|CRT matches to NC_014213 (Meiothermus silvanus DSM 9946 plasmid pMESIL01, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
atcgcccacttcaccggcgtttccgaccctt	Protospacer
* ************** **** *** * .. 

202. spacer 2.6|367196|33|NC_020559|CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 9, identity: 0.727

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttgtattcgatcccgatctggccgtcgccggcc	Protospacer
  *.  .******************.*****. 

203. spacer 2.6|367196|33|NC_020559|CRISPRCasFinder matches to NZ_CP016287 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
cggctgccgatcccgatcaggacgtctaccttc	Protospacer
 ***************** ** ***.  *  * 

204. spacer 2.6|367196|33|NC_020559|CRISPRCasFinder matches to NZ_CP022565 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence) position: , mismatch: 9, identity: 0.727

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
cggctgccgatcccgatcaggacgtctaccttc	Protospacer
 ***************** ** ***.  *  * 

205. spacer 2.6|367196|33|NC_020559|CRISPRCasFinder matches to NZ_CP048281 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence) position: , mismatch: 9, identity: 0.727

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
cggctgccgatcccgatcaggacgtctaccttc	Protospacer
 ***************** ** ***.  *  * 

206. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to NZ_CP014964 (Geobacter anodireducens strain SD-1 plasmid pSD, complete sequence) position: , mismatch: 9, identity: 0.71

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
ggaacgaacggcaagccgaaatgttggtgga	Protospacer
.* .**************** .*****    

207. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to NC_015974 (Sphingobium sp. SYK-6 plasmid pSLPG, complete sequence) position: , mismatch: 9, identity: 0.71

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
taagcgaacggtaagccgaaccgctgaggcg	Protospacer
 . ********.***********.**.. * 

208. spacer 3.1|693013|31|NC_020559|CRISPRCasFinder matches to NZ_CP005085 (Sphingobium sp. TKS plasmid pTK1, complete sequence) position: , mismatch: 9, identity: 0.71

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
taagcgaacggtaagccgaaccgctgaggcg	Protospacer
 . ********.***********.**.. * 

209. spacer 5.2|1090803|33|NC_020559|PILER-CR matches to NZ_CP051473 (Rhodobacter sphaeroides strain CH10 plasmid pRspCH10DE, complete sequence) position: , mismatch: 9, identity: 0.727

cttcggcggaattaacggcacgttcggcaccaa	CRISPR spacer
ggtcggcggcatgaacggcacgttcgccgacgc	Protospacer
  ******* ** ************* *. *. 

210. spacer 5.2|1090803|33|NC_020559|PILER-CR matches to NZ_CP051473 (Rhodobacter sphaeroides strain CH10 plasmid pRspCH10DE, complete sequence) position: , mismatch: 9, identity: 0.727

cttcggcggaattaacggcacgttcggcaccaa	CRISPR spacer
ggtcggcggcatgaacggcacgttcgccgacgc	Protospacer
  ******* ** ************* *. *. 

211. spacer 5.2|1090803|33|NC_020559|PILER-CR matches to NZ_CP030276 (Rhodobacter sphaeroides 2.4.1 plasmid pDE, complete sequence) position: , mismatch: 9, identity: 0.727

cttcggcggaattaacggcacgttcggcaccaa	CRISPR spacer
ggtcggcggcatgaacggcacgttcgccgacgc	Protospacer
  ******* ** ************* *. *. 

212. spacer 5.2|1090803|33|NC_020559|PILER-CR matches to NZ_CP030276 (Rhodobacter sphaeroides 2.4.1 plasmid pDE, complete sequence) position: , mismatch: 9, identity: 0.727

cttcggcggaattaacggcacgttcggcaccaa	CRISPR spacer
ggtcggcggcatgaacggcacgttcgccgacgc	Protospacer
  ******* ** ************* *. *. 

213. spacer 5.2|1090803|33|NC_020559|PILER-CR matches to CP047036 (Rhodobacter sphaeroides strain DSM 158 plasmid pDx, complete sequence) position: , mismatch: 9, identity: 0.727

cttcggcggaattaacggcacgttcggcaccaa	CRISPR spacer
ggtcggcggcatgaacggcacgttcgccgacgc	Protospacer
  ******* ** ************* *. *. 

214. spacer 5.2|1090803|33|NC_020559|PILER-CR matches to NZ_CP015289 (Rhodobacter sphaeroides strain MBTLJ-20 plasmid a, complete sequence) position: , mismatch: 9, identity: 0.727

cttcggcggaattaacggcacgttcggcaccaa	CRISPR spacer
ggtcggcggcatgaacggcacgttcgccgacgc	Protospacer
  ******* ** ************* *. *. 

215. spacer 5.2|1090803|33|NC_020559|PILER-CR matches to NZ_CP015289 (Rhodobacter sphaeroides strain MBTLJ-20 plasmid a, complete sequence) position: , mismatch: 9, identity: 0.727

cttcggcggaattaacggcacgttcggcaccaa	CRISPR spacer
ggtcggcggcatgaacggcacgttcgccgacgc	Protospacer
  ******* ** ************* *. *. 

216. spacer 5.2|1090803|33|NC_020559|PILER-CR matches to NZ_CP047042 (Rhodobacter sphaeroides strain 2.4.1 substr. H2 plasmid pDx, complete sequence) position: , mismatch: 9, identity: 0.727

cttcggcggaattaacggcacgttcggcaccaa	CRISPR spacer
ggtcggcggcatgaacggcacgttcgccgacgc	Protospacer
  ******* ** ************* *. *. 

217. spacer 5.2|1090803|33|NC_020559|PILER-CR matches to NZ_CP015212 (Rhodobacter sphaeroides strain MBTLJ-13 plasmid a, complete sequence) position: , mismatch: 9, identity: 0.727

cttcggcggaattaacggcacgttcggcaccaa	CRISPR spacer
ggtcggcggcatgaacggcacgttcgccgacgc	Protospacer
  ******* ** ************* *. *. 

218. spacer 5.2|1090803|33|NC_020559|PILER-CR matches to NZ_CP015212 (Rhodobacter sphaeroides strain MBTLJ-13 plasmid a, complete sequence) position: , mismatch: 9, identity: 0.727

cttcggcggaattaacggcacgttcggcaccaa	CRISPR spacer
ggtcggcggcatgaacggcacgttcgccgacgc	Protospacer
  ******* ** ************* *. *. 

219. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to CP054927 (Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
cccgccggccacgccggcggcggccagaag	Protospacer
********** ********.***. . .  

220. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 9, identity: 0.7

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
ggtcgcggccccgctggcgacggtggatgt	Protospacer
  .  *********.***********   *

221. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to CP053415 (Salmonella enterica strain 2011K-0868 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.7

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gggcacggccccgtcggtgacggtggcggc	Protospacer
     ********.***.********** .

222. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to CP053327 (Salmonella enterica subsp. salamae serovar 58:c:z6 strain 2013K-0366 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.7

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gggcacggccccgtcggtgacggtggcggc	Protospacer
     ********.***.********** .

223. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP030289 (Salmonella enterica subsp. enterica serovar Gaminara str. SA20063285 plasmid pIncI1.1, complete sequence) position: , mismatch: 9, identity: 0.7

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gggcacggccccgtcggtgacggtggcggc	Protospacer
     ********.***.********** .

224. spacer 15.5|3724179|34|NC_020559|CRT matches to NZ_CP021805 (Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence) position: , mismatch: 9, identity: 0.735

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
attgagatccgcgacgatgggtgtggcgccggcg	Protospacer
.**    .********.**** ***********.

225. spacer 15.5|3724179|34|NC_020559|CRT matches to MG812496 (Gordonia phage SallySpecial, complete genome) position: , mismatch: 9, identity: 0.735

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
gcgcaccaccgcggcggtgcgggtggcgccggcg	Protospacer
*. . *. *****.***** *************.

226. spacer 2.6|367196|33|NC_020559|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 10, identity: 0.697

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttgtactcgatgccgatctggccgtcgccggcc	Protospacer
  *.  .**** *************.*****. 

227. spacer 2.6|367196|33|NC_020559|CRISPRCasFinder matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 10, identity: 0.697

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttgtactcgatgccgatctggccgtcgccggcc	Protospacer
  *.  .**** *************.*****. 

228. spacer 2.6|367196|33|NC_020559|CRISPRCasFinder matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 10, identity: 0.697

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttgtattcgatgccgatctggccgtcgccggcc	Protospacer
  *.  .**** *************.*****. 

229. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to NZ_CP011274 (Planctomyces sp. SH-PL62 plasmid pPL62-1, complete sequence) position: , mismatch: 10, identity: 0.667

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
gttcccggccccgccgtcgacggtgatcgc	Protospacer
 .. ************ ********..  .

230. spacer 13.9|3106506|35|NC_020559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 10, identity: 0.714

acttgcgcgcacaacgcatccgccatccacggggc	CRISPR spacer
gtcaccgcgcacaacacattcgccatccacacggt	Protospacer
...  **********.***.**********. **.

231. spacer 14.22|3109706|34|NC_020559|CRISPRCasFinder,CRT matches to NZ_AP022335 (Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49c, complete sequence) position: , mismatch: 10, identity: 0.706

tagaaggcgatcactggaagcacggcgcttgcga	CRISPR spacer
ggcaaggcgatcagtggaagctcggcggcggcac	Protospacer
 . ********** ******* ***** . **. 

232. spacer 14.38|3109710|34|NC_020559|PILER-CR matches to NZ_AP022335 (Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49c, complete sequence) position: , mismatch: 10, identity: 0.706

tagaaggcgatcactggaagcacggcgcttgcga	CRISPR spacer
ggcaaggcgatcagtggaagctcggcggcggcac	Protospacer
 . ********** ******* ***** . **. 

233. spacer 15.5|3724179|34|NC_020559|CRT matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 10, identity: 0.706

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
cagcgcggccgcgtcggtgggggtggcgcccgcc	Protospacer
   . *  ***** **************** ** 

234. spacer 15.5|3724179|34|NC_020559|CRT matches to NZ_CP024986 (Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence) position: , mismatch: 10, identity: 0.706

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
gagaccgcccgcgatggagggggtggcgccgagc	Protospacer
*   .* *******.** *************.  

235. spacer 15.5|3724179|34|NC_020559|CRT matches to NC_024970 (Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 10, identity: 0.706

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
gagaccgcccgcgatggagggggtggcgccgagc	Protospacer
*   .* *******.** *************.  

236. spacer 15.5|3724179|34|NC_020559|CRT matches to NZ_KJ396772 (Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 10, identity: 0.706

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
gagaccgcccgcgatggagggggtggcgccgagc	Protospacer
*   .* *******.** *************.  

237. spacer 15.5|3724179|34|NC_020559|CRT matches to NZ_CP029831 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence) position: , mismatch: 11, identity: 0.676

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
cgcccccggcgtgacggtggaggtggcgccggcc	Protospacer
  ...*.  **.********.************ 

238. spacer 7.1|1625779|30|NC_020559|CRISPRCasFinder matches to MK801723 (Gordonia phage Coeur, complete genome) position: , mismatch: 12, identity: 0.6

cccgccggccccgccggcgacggtggcgtt	CRISPR spacer
ctgttcaccgccgccggcgtggccggcgtg	Protospacer
*.  .*. * *********  * .***** 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	2929429 : 2967701	47	Mycobacterium_phage(30.0%)	tRNA,protease,head,integrase,terminase,capsid	attL 2958230:2958257|attR 2967854:2967881
DBSCAN-SWA_2	3086894 : 3112923	27	Burkholderia_virus(50.0%)	integrase,tRNA,transposase	attL 3096773:3096791|attR 3121316:3121334

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_020559|2929429:2967701|DBSCAN-SWA
GTCACTCACGACCGGCCACTTTCACCAGTTCCGCTGTAGGAACCGCATTTTCGCGGTCAGCGATCCAGGCGACAATGGCCGCCACCGCATCGTCACGGGCCACACCGTTGATTTGGGTGCGGTCACCGAACCGGAAACTCACCGCGCCGGCGGCGACGTCACGATCACCCGCCAACACCATGAACGGCACCTTGTGGTTGGTGTGGTGCACGATCTTCTTGGCCATCCGATCGTCGCTGGCGTCCACCTCGGCCCGCACCCCGTGCGACTTCAGTTGCGTGGCAACCTCTTCCAGATAGGCGACGTGCTCATCGGCGACCGGGATGCCGACCACCTGCACGGGCGCCAACCAGGCCGGGAACGCCCCCGCGTAGTGCTCGGTGAGAATGCCGAAGAACCGCTCGATCGACCCAAATAGCGCGCGGTGGATCATCACCGGGCGGTGGCGGGTTCCGTCGGCGGCGGTGTACTCCAGGCCGAAACGTTCCGGAAAGTTGAAGTCCAGCTGGATGGTCGACATCTGCCAGGTGCGGCCCAGCGCGTCTTTGACCTGCACTGAAATCTTGGGCCCGTAGAACGCCGCGCCGCCTGGATCGGGCACCAGCTCCAGCCCGGATTCGGCGCCCACCTCGGCCAGCACGGTGGTGGCTTCCTCCCAGACCTCCTCGGCGCCGACGAACTTCTCCGGGTCCTTGGTGGACAGTTCGAGGTAGAAGTCGGTGAGGCCGTAGTCGGCGAGCAGGTCGAGCACAAACCGCAGCAGCGACCGCAGCTCGTCGCGCATCTGGTCGCGGGTGCAGAAGATGTGCGCGTCGTCCATGGTCAGCCCACGCACCCGGGTCAACCCGTGCACCACACCGGACTTCTCGTAGCGATACACCGTGCCGAACTCGAAGAGCCGCAACGGCAGTTCCCGATAGGATCGCCCGCGCGCGCGGAAGATCAGGCAGTGCATCGGGCAGTTCATCGGCTTGAGGTAGTAGTCCTGGCCGGGTTTGCGCAGCGAGCCGTCGGCGTTGTACTCCGCGTCGATGTGCATCGGGGGGAACATGCCGTCGGCGTACCAGTCCAGATGTCCCGAGGTGTGGAACAACTGGGCCTTGGTGATGTGCGGGCTGTTGACGAACTGGTAGCCCGCCTCGGTGTGCTTGCGCCGCGAGTAGTCCTCCAGTTCGCGACGCACGATGCCGCCCTTGGGGTGGAAAACCGCTAGGCCGGAACCGATTTCGTCGGGGAAGCTGAACAGGTCCAGCTCGACACCCAGCTTGCGGTGGTCGCGGCGCTGCGCCTCTTCGATGAACTCCAGGTGCCTGTCGAGCGCCTCCTGGGATTCCCACGCGGTGCCGTAGATCCGTTGCAGGCTGGCGTTTTTCTGATCGCCCCGCCAGTAGGCGGCCGAGCTGCGGGTGAGCTTGAACGCCGGGATGTGTTTGGTGGTCGGGATGTGCGGTCCGCGGCACAGGTCGCCCCAGACGCGCTCGCGGGTGCGGGGGTTGAGGTTGTCGTAGGCGGTGAGCTCGTCACCGCCGACCTCCATGATCTCGGCGTCACCCGATTTGTCGTCGACGAGTTCCAGCTTGTAGGGCTCGTTGGCCAGCTCGGCGCGGGCCTGTTCGGTGGATTCGTAGACCCGCCGGTCGAACAGCTGGCCTTCCTTGACGATCTGGCGCATCCGCTTTTCCAGCGCCGCCAAGTCCTCGGGCGTGAACGGCTCGGGCACGTCGAAGTCGTAGTAGAAGCCGTCGGTGATGGGTGGTCCGATGCCGAGCTTGGCCTGCGGAAACAGCTCTTGGACGGCTTGGGCCAACACGTGCGCGGTCGAATGGCGGATCACGCTGCGACCGTCGTCGGTGTTGGCGGCCACCGGCGTGATATCGGTGTCGACGTCGGGCACCCAGCTCAGGTCGCGCAGGTTGCCGTCGGCGTCGCGCACGACGACGATCGCATCGGGCGTACCGCGCCGCGGTAAACCCGCTTCGCCGACGGCGGTGGCCGCGGTGGTCCCGGCAGGAACCCGAATTCGGGCTTGCGACGGGTCGCCGCCATCGACTCCCGGGGCGGGTTGTGCGGGGGCGCTCATCGGGTCGGTCTCCAAGGCTTGGACGTGTCGAAACGATCGCGACCATGCTATCGGGGCGCACGTCGACGACCGTAAGCCGAGTGACCGGATGGGTTTTCGATCACCGGTGTGGGCGATCGGTACCGGGCAGGTGACCGGGTGCTCTACGGCGGCTCGATGAGCCCAAAGGATGTTGACGACCTGGCTACCCAGCAGGACGTCGACGACGGACAGTCGATAGAGCGTCGCTGGACGGGGAGCGGTCAGCGACGCTGGCGGCGGTCGCCGCCGACGGGCCGCTACCGTAGCAACTCGCAAATCCAGGTCTGGATTTCCGGCGCCGGCCGGCTCCGTTAGCCGTCGGCTCCGTTGGTGCCGGCCAGGCCGGGTGGCCCCAACAGTGATGCACCGCCGCTGCCGCCGGGCCCGCCGAAGCCTGGAGCGCCATTGAAGAGGCTCCCGGCGCCGCCGTTTCCGCCGTTTCCACCGTTGCCGATCAGTCCGACGCTGCCGCCGTTCCCGCCTTTCCCGCCGTCACCGCCGGACCCGCCAGCAGTGCCGGCGCTCGCTCCGTTCCCGCCGGCCCCGGCGCTCCCACCGGCCCCCGCGTTGCCGATGAGGGCATTGCCGCCGTTTCCACCGCTGCCGCCGCTACCGCCATTCCCTCCGAAGGCCGTAACAGACCCGGGCGACCCGGCGGCACCGCCGTTTCCGCCGGCCCCGCCGTTACCGTAGAGTAGCCCGCCGGCGCCGCCGTTACCGCCTTGCCCGCCAAACCCAACGCCCCCGAAATCGGCGGACACATCACCACCGGCTCCGCCGGCTCCGCCATTGCCGCCGTTGCCGATCAGTCCGGTGGTTCCGGCGTGACCACCGTTACCCCCGAATCCGGACGCTGGACCGTTCTGAGAAATGCCTGCCCCGTTTCCGGCGGCCCCGCCGTCCCCGCTGTTGCCGATCAGTAGGCCGCCGTTCCCGCCGTTCCCGCCGTTGCCGCCGCTAGCCCCCGCGGAGGGCTCGCCGCCGCCGGTGCCCCCGGCCCCGCCGGTCCCGCCGGCGCCGATCAGCCCGGCGTTGCCGCCGTTCCCACCATGCCCGCCGATAGCGAGGTTGGTGCCGGCCCCACCGATCCCGCCGTTCCCGCCGGCCCCGCCGTTGCCGAACAGCCATCCACCGGCGCCGCCGGCTCCGCCGTTCGCGCCGGCCTCAAAGGGTAGGCCCTGGCCGCCAGCTCCGCCGGCCCCACCGTTGCCGATCAACCCGGCCGCACCGCCGGCCCCGCCGGCCTGCCCGGGTGCCCCCGACCCGCCGTTGCCGCCGTTGCCCCACAGCCACCCGCCGTTACCGCCGGCTTGCCCGGTCCCGTCGATCCCGTTCGCGCCGTCGCCGATCAATGGGCGCCCGGTCAGCGACTGAACGGGTGCGTTGATCGCATCGAGCACGTTCTGCAGCGGTGTTGCGCTGGCCGCTTCGGCGACCGCGTAGGTGCTGCCAGCTTGGCTTAAGGCCAGCACGAACCGTTGCTGATAGGCCGCGACCTGCGCGCTGATCGCTTGATAGTGCTGGCCGTGGCTGCCGAACAGCGCGGCGATCGCCGTTGACACCTCGTCTTGGGCGGCGGCCAACACCTGGGTGGTCGCCGCCGCCGCGGTGTTGGCGGTGTTGATCGCCGAGCCGATCCGCGCTGCATCGGCCGCGGCTGTGGACACTAACTGTGGGGCCACGTTGACAAACGACATCGAAATCCTCCTGACCGCCACGATGTTGAGATGCGGGCGGCCCACCGCCTGTTACCGCCGCGGTGGGTAACCGTTTATTCGGACGATCCCTGCCGTTCCACGCCTGGGCGCAGGCACAAACCGCACCAACATTGGTGGAACGTGGTGCACACTGCACCTGGGGTTCTGCCCTCATCGTGTGGCAGCAGGCGAAACCCGCGCGGACGAGAACTCTTCCGCCAAGCAGCACAAATCGCCCTACACCCCAGTGAATCTCCGGACGCCACTACGACAGCGCGCAACGGTCGCCTCATCGACTGTGTGCACGCGCGCTTCGCGATGCGCTGCCGTGGCAAGCTGGCCAGGTGGACCTCAATGCGCTGGCCGATCTGCCGCTGACCTATCCGGAGGTGGGCGCGACAGCGACCGGACGACTGCCCGCGGGCTACAACCACCTTGACGTGTCGACGCAGATCGGCACCGGCCGCCAGCGTTTTGAGCAGGCCGCCGACGCCGTCATGCATTGGGGCATGCAGCGCAACGCCGGCCTGCGGGTGCGGGCCAGCTCCGAAACCGCCGTCGTGTCCGCGGTGGTGTTGGTGGGAATCGCTTTCCTGCGTGCGCCGTGCCGAGTGGTGTATGTCATCGACGAACCCGACGTGCGCGGATTCGGTTACGGCACTTTGCCGGGCCATCCGGTGTCCGGCGAGGAACGGTTCGCGGTTCGCTGCGACCCGATGACCTCCGTGGTGTTTGCCGAGGTGTTGTCGTTCTCCCGTCCGGCGACCTGGGCGAGCAAAGCCGCCGGGCCGCTGGGCGCGGTGACCCAGCGCTTCATCGCCCAGCGCTACCTGCGCGCGGTGTGAGGCGCCGGCGCCCTGGTTAAGGCCGCCCGATGCCTCCGCTGTGCACGCCCTGCGCCAGCCGGGCGAGCGCGATGGCGCCAACCAGCAAACCGAAGTCGCGCAGCGCGATGTCGTAGAAACCGGGTCCGGTGACCAGGTTGAGAATGATCCCGGCCAGCCAGGCCGCGACTACCCAGGCGCCGATGCGCGGTGCGACCGCAACCAATACGCCGGCCACAATCTCGATTGCCCCGACCAAGTACATGCATTGGTCGGCGGTGCCGGGCACGAGATCGTTGATCCAGCCGGCCAGATACATGTTCCAGTGCTGCGGATGGGTCAGCAGATTGAAGAACTTGTCCAGCCCGAACAGGATGGGCGCGACCGTGAACAGCGTGCGAAGCAATACGTATGCAGAGTATGCCGGATCCTTCAGCTGGTCTGCGAGAGCAGGGCTGGTCGTTGGTCTGATGCTCATAGCTGCCTCCCGACTTCTAACAGACAACAATTTGAACGTTAGATCCTATAGACTGTATCGTCAAGTGTTTTGTCTGTTAGAGATGGCTTGCTGAAGTGGACGGCCGAGCTTCCTTCGAACGCGACGTCGCCGGGATCGGGGCACTCGTGGATCCGGTGCGTCGCCAGCTCTACCAATTCGTGTGCTCACAATCGATGCCGGTGAGCCGAGACCAGGCGGCCGACGCCGTCGGCATCCCGCGCCACCAGGCGAAATTCCATTTGGACCGGCTCACTGCCGAAGGCCTGCTGGATACCGAGTACGCGCGCCTGACCGGCCGGTCCGGCCCCGGCGCCGGGCGGACCGCCAAGCTGTATCGCCGGGCCGGCCGCGACATCGCCCTCAGCCTTCCACAGCGGGAGTACGAGCTTGCTGGGCGGCTGATGGCCGCAGCCATCGTGCTGTCGGCCACCACCGGGGAGCCGACCGTGGAAGTGCTCAACCGGATCGCCCATGACTACGGCCAAGCCATGGGCGCCGCCGCCACCACCCGGCCGCCCGCAGACCCCGCGGCGGCGCTGGAGCTGACGCTGGATGTGCTGCGCAAGTACGGTTATGAACCCCGCCGCCCGGCTGGCCCTGGCGACGATGAGGTCGAGCTGGTGAACTGCCCGTTCCACGCACTGGCCCGGGAGCAGACCGAGCTGGCCTGCAATATGAACCACGCCTTGATCACAGGCGTGGCCGACGCGCTGGCACCGCACAGCCCGGCCGTTCGGTTGGCACCCGGACCGGCCCGGTGTTGTGTAGTACTCAAGCGATGTTCGGCTCACGACCCCGAGTGAGCATCGGGCAGGGATTTCAGCACGGTCAGCATGATCACCGAATCCTCGACGGCGTGCAGCGCATGCCGTGTCGGCGGAATCGCGACGTAGTCGCCGGCCCTGCCGTTCCACGCGTCCTCACCGGCGGTAAGGCACACATGGCCCTGCAGCACTTGCAGCGTCGCCTCGCCCGGGCTGTCATGCTCGGACAGGTCGTGGCCGGCAAGCAATGCCAGCACCGTCTGCCGAAGCTCGTGGGTGTGACCACCGTGGATGGTGTGGGCAGCCCGTCCGCTGTGTGTCTGTTGCGCCTCGGCCAGCTTTTCGGCGGCCAGGCTGGTCAGCGAAATGGATTCCATCGGCGCGTCCTTTCAGCCGTTCAGTAGCAGTATCCCCGCGACGAGCAACGCAACCACCTTGACTATCTCCAAACCGACATAGATGTGGTGACCGCGGGAGCGGGGAGCCTGCAGCCCGGCCAATACCTGATTGGACCGTCGAGTCAATCGAGGACGCACCGCAATCAACTGGACGGCCAACGCAGCCAACGCGACCGAAAACGCCGCGGCGATCCGCGCCGGCGTCGAGCCGACCACCACGATCGCGAGGATGACAAGGGCGAAACCGACCTCAACGGTATTGAGCGCACGGAAGACCAACCGGCCGATGCCGAGCCCGATCTGCAGCGTCACTCCTGCCGCCCGGAACTTCAGCGGAGCTTCCAGAAACGAGATCGCCACCACCATTCCCAGCCAGACGAACGCGACGGCGACCTCGATCGCCGGTCCGGCGCTCACCGAATGGCTCCTTCCAGCGGCGTGAAGTGGGCCAGGCACAGGTCGGGTTCGACGAACGCGTCGAGCCGGTCGACGGTGACTGGCGCCCCCCATGTTTGCAAGGCTCCCCGCATGATCCCTAAGTGGACGGGGCAGACGACACCGGCTTGAGTTTCGGCGAGTTCCAGAAACGGACAGTGCCGCAGACCGACCTGTTGCCTGCCGTTGGATGCCCGGCGCTCGGGAGCGAAGCCAAGGTCGTCAAGCACCGCGACCAAGTGGTCGATCGTCTCCTCGGTGTCGGCACCGGCCGGCGGCGCTTCGAGCTGGCGCCCCCACGCCCGGCCCGCGGACAACGCCATGGCCCGCGAATCCCGTTCGGCGGCAAGGCCACTGGCGAGGATCTCGGCAAGCAGCCGGTAACGCCGCGTCCCAGTGCTATCCGTCCGCCGGACCGCCCGAAACATCAGCGGCGGGCGCCCCGGTCGGCCGCGGCCGGGCTCGACCCGCTCCACCTGGCCATCAGCGACCAGGTTATCGAGGTGGAAGCGGACGGTGTTGGGATGCACGCCCAACTTGCCGGCGATCGCGGCGATGCTCATCGGAACCCGCGACGCACACAATGCCCGCAGCACCGCACGACGGCGCCCCACCGGCTCTTGCAGTGACCTGATGATGACACTCACCCCCATAAGGCTCGTCGGCTGCGCCTGAGCAATGCAGTAAGTTTACACAAACGGACTTGTAAAAACCTGCGGAGGTGGGGTCTATGGCCAACAAACGTGGCAATGCCGGGCAGCCTCTGCCCTTGTCGGATCGAGACGACGACCACATGCAGGGGCACTGGCTGCTGGCCCGGCTGGGCAAGCGGGTGCTGCGTCCCGGCGGCGTCGAACTCACCCGGACACTGCTGGCCCGCGCCGAGGTGACCGACGCCGACGTGCTCGAGCTGGCACCGGGCCTGGGCCGCACCGCAGCCGAAATCTTGGCCCGCAACCCGCGGTCGTACGTGGGGGCGGAGAGCGATCCCAACGCGGCCAACCTGGTCCGACACGTTCTCGCCGGCCGCGGCGACGTCCGGGTCACCGACGCGGCCGATACCGGATTATCCGACGCCAGCGCCGATGTCGTCATCGGCGAGGCGATGCTGACCATGCAAGGCAACGCGGCTAAACACACGATCGTCGCCGAGGCGGCGCGGGTGCTGAGGCCGGGTGGCCGCTACGCGATTCACGAACTAGCGCTGGTGCCGGACGACGTCGCAGAGCAGGTCCGCACCGACCTGCGGCAGTCGCTGGCCCGCGCGCTCAAGGTCAATGCGCGTCCGCTGACCGTTGCGGAATGGTCGCACCTCTTAGCGGGCCATGGACTGGTCGTCGAACACGTTGTCACCGCTTCCATGGCGTTGTTACAACCGCGACGGGTGATCGCTGACGAAGGCCTCCTGGGTGCGCTGCGGTTCGCCGGAAACCTGCTCATCCATCGTGCCGCGCGTCGGCGAGTCCTGTTGATGCGCCACACATTCCGCAGGCATCGTGAACGCTTGACAGCCGTCGCCATTGTCGCGCACAAACCGCACGTCGATTCGTGATCCATTGAGGACCTAAGCCCGTTGGGCTAGTGACAAACGCCTCCTGAGCAAAACCCTCCTCCCCCGTTACCGTCGTGCGGTAGGGACAAGCCACATCGGCCGAGCGGGCGATCAGCCAACGACAGGAGGACCGCGATGTCATCGGGCAATTCATCTCTGGGAATTATCGTCGGGATCGACGATTCACCGGCCGCACAGGTTGCGGTGCGGTGGGCAGCTCGGGATGCGGAGTTGCGAAAAATCCCTCTGACGCTCGTGCACGCGGTGTCGCCGGAAGTAGCCACCTGGCTGGAGGTGCCACTGCCGCCGGGCGTGCTGCGATGGCAGCAGGATCACGGGCGCCACCTGATCGACGACGCACTCAAGGTGGTTGAACAGGCTTCGCTGCGCGCTGGTCCCCCCACGGTCCACAGTGAAATCGTTCCGGCGGCAGCCGTTCCCACATTGGTCGACATGTCCAAAGACGCAGTGCTGATGGTCGTGGGTTGTCTCGGAAGTGGGCGGTGGCCGGGCCGGCTGCTCGGTTCGGTCAGTTCCGGCCTGCTCCGCCACGCGCACTGTCCGGTCGTGATCATCCACGACGAAGATTCGGTGATGCCGCATCCCCAGCAAGCGCCGGTGCTAGTTGGCGTTGACGGCTCGTCGGCCTCCGAGCTGGCGACCGCAATCGCATTCGACGAAGCGTCGCGGCGAAACGTGGACCTGGTGGCGCTGCACGCATGGAGCGACGTCGATGTGTCGGAGTGGCCCGGAATCGATTGGCCGGCAACTCAGTCGATGGCCGAGCAGGTGCTGGCCGAGCGGTTGGCGGGTTGGCAGGAGCGGTATCCCAACGTAGCCATAACCCGCGTGGTGGTGCGCGATCAGCCGGCCCGCCAGCTCGTCCAACGCTCCGAGGAAGCCCAGCTGGTCGTGGTCGGCAGCCGGGGCCGCGGCGGCTACGCCGGAATGCTGGTGGGGTCGGTAGGCGAAACCGTTGCTCAGCTGGCGCGGACGCCGGTCATCGTGGCACGCGAGTCGCTGACTTAGGTTCAGCGGCGAACGACAAGCACCGAACACTCGGCGTGACGGAACACCGGATGTCCGGATGGCCCGACCAGCCGCGCTAGCTGACCGGCCTCACCACCGCCGATCACTGCCAGCTGTACGCGCTCGTCGTGGTCGGCCAGGAACCGGGCAATACCCGTGTGAGTGGTGATCGGGTAGACGCGCACATCGGGATGACGGTGGTGCCAATCCTGCACGCGACGTTCGAATTCGCCGTCCGGAATCTCCCGGAGCTCCTCCGGTCGCCCGCCGAGTGCCAGTATGGGCGCTTGCCGCAACTTCGCTTCCCGGGCAGCGTATTCCAGCACGGCCTCGTTATCCGGTGCGTCGGTCATGCGCACCACGATCCAGTTGATGTCAGACGCTGGCTGGTCCACTTTTGAGCGCATGACGGCGACCGGGCAATGCGCCTTTTCGGCCAGCTCGGTTGCCGTCGAACCCAAGATCGAGCTGGCGTAGCGCCCGATTCCCACGGAGCCGACGCAGATCATCTCGGCGTCGCGCGATGCCTCCACAAGCACCGGGCCGGCTGGCCCGCGGGGGATGTCGGTTTCGATCTTGACGAGCTTGCCCGCGGCCTCAACAGCGGACTGCGCTTCCCGAAGCGATCTTTCAGCATGCGCAAGGTCGCGGTCGTAGTCGTCCGGGGACGGATGTGTCGGCTTGATCACTGAGACCAGTCGCAGCGGCACCGCTCGGCTGATGGCCTCGTCAACCCCCCACAATGCGGCCGTAATCGCCGCGTGCGAACCATCGATACCAACAATGATTGTTTTCATCGTCGGCTCTCCTCTCCCAGACATTTCCCGATGCTCGATCACCCCGCATCGGAAAACCTGTCCGCATCTTGGGGACTCGTGGTAAAGGTCGGTTCCGGCTGGGCCAACCGGTAGACGTCAATCAGCCGCGCGACATCGCTGGGAGTGACGATGCCGACCACCGCGCTCCCTTCGGTGACCAGCGCACGGCTGCGCGGGCCGAGCGGTGCCATCCGCTCTAGGAGCGCGGTCAGCGGCTCTTGTGGTCGGGCGGTCGGCACGCTGTGCAGCGGCAGCGCAATGTCACCTACGCTGGTAGTGCTGCGCCGGCTAGGCGCAACATCGCGCAGCTGCCGCAATGCCACCAGGCCCGTGATCGATCCGTCCCGATCGGCAACCGGATATGCCGAGTGCCGTTCACCAAGCACGTAACGCTGGATGAAATCCTCGACATTGATCCATCCGGGAGCCGTATGCGGTTGGGCGGTCATCGCATCGGCCACACGCACCCCGGCAAACAGCTGCTGGGTCGAAATCCGGGTCTCCTCCTCGCGAGCGGCAGCGAAGATAAACCAGCCAATGAAGGCTAACCAGACCCCACCGACGAGGCCACCAGCCACAAACTCGGCCAATCCCAACGCGATCAAGACCAGCGCAACCACCCGTCCGGCCCGCGCCGCACCGATCCCGGCGCGCACACTATCGCCGTGGCGGCGCCACAGATAGGCCCGGACCAACCGCCCACCGTCCAACGGCGCGCCAGGCAGCAGATTGAACAGCCCCAGCAGCAGGTTGACAGTAGCCAACCACCAAGCAACGCTGATCACGATGGCCGGGGTCCGCACGCCGGCGAGCGTGATGGCCAACGCACCGAATGTCGCCGACAGCGCCAGGCTGGTAGCCGGACCCGCGAACGCGATCCGGAAAGCGGCTTTGGGCGTCTTTGCCTCGCCGCCAAGCGCGGTCACCCCGCCGAACAGCCACAACGTCACGCTCTCAACGGATACCCCGGCGCGACGAGCGACGACGGCGTGCGCGAGCTCATGAGCCAACAGCGACGCCAGCAACATGACCGCGCCACCTGCGCCGAGAAGCCAATAGACCACGGCCGGGTAGCCTCCGACGGTACCCGGCAACATGGTCGCCAGACTCCAGGTGAACAACCACAGGATCACCAACACGCTCCAGTGGACGTTCACCACAAACCCGGCGATCCGCCCAAGCGGGATCGCATCACGCATTGGGTACCTCCGATGCTGGCGGATAAAGCCTTTCGTGCCGGCGGATGATCCGAGGTCGCTAGCTGGCGAGGGCCATGGGCGAGCAGATTGCCTTGACGAACTGCACAATGGCGTGCTCGGGCAGGTGTCGGGCGATGTCGGCTTCGGTGACGATTCCGACCAAGCGGTGCTCTGAGATGACCGGAACACGGCGGACCTGATGTTCTTCCATGACGTTGAGCATCTCCTGGATGCTTGCGTTCGCATCGACGTAGTAGATGCTGTCCCGGGCCAACTCGCCAGCCGTGGCGGTATTCGGGTCTAGGCCCGCAGCCAGGCCTTTGATCACAATGTCGCGGTCGGTGAGCATGCCGTGCAGCCGGTCGTCGTCCCCGCAGATCGGCAACGCGCCGATGTCGTGCTCACGCATGTATTGAGCGGCAGCGGTTAGCGTCTCGTGTTCGCCAACACAGGTCACACCTGCGTTCATGATGTCGCGTGCGGTGGTCATCGGGATCCTCCTCGAGTCGGGGTGCTATTGCTGATCTGCTGCCGAAGGTACGACCACGTCGTAGCGAACACTAGGGTCGTTTGACCCGTGGGCCGCGGGTCGATGGACCCGTACTGGCGCGCGTTGAGGCAGCTGGCTTGCCTGGCTTGTCCTCGCCGTAGGCCACCTCAAAGTCGAAGGTTGTCAATTGATTTCACCAGCCGGATATAGCGCTATGGGCGGCCGCAGGACCGATAGTGATGCCGATCGGCCCCGATCGGGGTAACCGGCAATGGAACAACTGACAACCATGAAGGCTCGTTTCGACGGAAGCGGAAGACGCCGACAGGCACATGAGCCTCGCGACGGGGCCAATCCGTTGGCTTTGCGACCGCGGTCGTAGGTCCTGGCGGAGCCGGGTTGCCACATCCGTCACAAGCTGACACGCCGAACGTGCAACCAGGGCGGCATCGCCTGGGTGTGTCTCCGCCACCAGTGCACATTCGGCGCAGCCAGCCCACGCTCGGCGCGGAGTTAGGCGGAACGGTCGCGCTGTGTCCGTGGCGCGTCCAACAGGCCCGACTGCTCCAGCGCAGCCTGGACAAACCGTCGTACCGGCCGCGACTGGAAGAAGCCAGTGTGACCGCCTGGATACCACACGATTTCGGGTTTGCCCCAGTGCTCCCAGAGGCGAGTCACCTGTTCGCGTGGATGCACGAGTCGGTCGGCAATGCCCGCGTAGATAAAGCGGCCCGGCATGGGCACCAGTGGCGTAAGTGAGAGCGGCGAGATCATTCGGCCGATCGGTTCGGCCATCTTGACGGTGTGGCGGCGGGGGTCTTTGTGCCGAAGACCGCAGTGGCGGCCCAACAACTCGATCAGATCAGCCACTGGGACACCGAGAATCGCGCAGGCGAGACCTTCTTCGAGGCTGGCGACCAATGACGCGATGTAGCCGCCCAGCGAGAGACCGTTCAACCCGATCAGCGACTCCTCCTCCTGCGATCGTATCCAGGACAACAGCCGCCGGATATCCCACACCGCTTGAGCCGTCCCATGCACATCGTCGAGAACATCTTCTCCGGGAAAAACGGCGCCCTTCGGCAGACCTTGCCCGCGGGGACCATGCATCGGAAGAACCGGCATGACAATGTTCAGGCCGAGTTCGTCATGCAGCTTCCAGGCGCGGAACACCGCGAGATCCAACGGGGCCCTGCCCATCTCGGTGCCGTGTACACAAACCAGCCAGGGACGCGGCTCTGGGTGCCGCAGTAACAGGGCGTACTCGCGATTGTTCGCAGTGTATGAGAGCCACCGTTGGCTGCCCGGTTCACCCGGATGCGGCGTAAACCCACTGTCGAAGAAGATGCGATAAAAGGAGCGTCTGCGGTCCTTGACCTTTCGGACCGCGACCTCGGTGAGCGGTGGGGGCTGGGCAAAAAATCCGCTAGGCTTCTCCAGCCATCCGCGATTCCCATAGAACTCCAGTCCAGCGGCCACTTCTTGGCTGATGCGCTCGAACACTCGATGATTGCTGACCGGACGTCGTGCCTTGAGGCCCAGCAGGACGATTTCGTCTCGAAAGGCTTGCGCCGCTAAGGCAATAGTGGGCCGTGCGATCGGCAGTTTATCGGGCTGTTGACCCAGATAGTCGCGCCACGATTGAGCGACGTACAGACCGGTGTGCATGAACGGTCCCATGGCGCCGCTCAAGACCGGTGGACTCAGGCGAAAAGCCGAGCGTTCGTGGGTGCCGTCGCTCGCAGAACTTGCCATGGCAGCAAAGCTAACCGCGTGCGGAACGACGCGTTAGGGACTTACGTCCCGCCGGAAGTCACCTGTGTGGTGGTGGCCACTGTCGAGACCGGCGGCCCGTTGTGGTGGCCCAAGTGCCCTAAGGTGATCAGGTGCCGCAGCCCGGCCAGCACGCCGTCAGAGTTTCACGGGGCTTGGTCGCGGCCGATGGCGTCCTCATCGTGGGGTCGATGACCGAGGTGGACGCGGCGCGACCGGGCACATCGACGGTCCCCGGGGCTTTGTGGGCCAGTGAAGTGACGAAAGACCCCAGTGGACACGGACTTCGGCATGTCCACGCAACGACCGAGGCACTCCGGTATTCGGGCTGTTGGCCCCTACGCATGGGCCGGCCGATGTGGTCGGATAGGCAGGTGGGGGGTGCACCAGGAGGCGATGATGAATCTAGCGATATGGCACCCGCGCAAGGTGCAATCCGCCACCATCTATCAGGTGACCGATCGCTCGCACGACGGGCGCACAGCACGGGTGCCTGGTGACGAGATCACTAGCACCGTGTCCGGTTGGTTGTCGGAGTTGGGCACCCAAAGCCCGTTGGCCGATGAGCTTGCGCGTGCGGTGCGGATCGGCGACTGGCCCGCTGCGTACGCAATCGGTGAGCACCTGTCCGTTGAGATTGCCGTTGCGGTCTAAGCACCACCTAACGGTGTCGTCCCGAAGGGACGATTGCCGATCCGGTGGATGACTTTGGTCCCTATGCCTTCCCGCTGGACCGCACAACGATCGAAGGTGCCACGACGCATAGAAGACATGGCCATGCCACACCCTGATAGCATTGCAGCAAGCTACATGTACTGCTCTACCAGGATCCTTATGGGCAACAGTGGGTTTGAGTTATGAAACCCGTGGGCACATACCCTTCCGCGTCGTACTGGTCAGTCTCGACAGCGAAGAGATCACCGGTTGATCCACCAAGCATGCATTGGCGGGCATCTGCATAAACGGTGACGTATCAGCACAAAACAGCGGAGAGAACAACATGCGATCAGAACGTCTCCGGTGGCTGGTAGCCGCAGAAGGTCCGTTCGCCTCGGTGTATTTCGACGACTCGCACGACACTCTTGATGCCGTCGAGCGCCGGGAAGCGACGTGGCGCGATGTCCGGAAGCATCTCGAAAGCCGCGACGCGAAGCAGGAGCTCATCGACAGCCTCGAAGAGGCGGTGCGGGATTCTCGACCGGCCGTCGGCCAGCGTGGCCGCGCGCTGATCGCGACCGGCGAGCAAGTACTGGTCAACGAGCATCTGATCGGCCCACCACCGGCTACGGTGATTCGGCTGTCGGATTATCCGTACGTCGTGCCATTGATAGACCTTGAGATGCGGCGACCGACGTATGTATTTGCCGCGGTTGATCACACCGGCGCCGACGTCAAGCTGTATCAGGGGGCCACCATCAGTTCCACGAAAATCGATGGGGTCGGCTACCCGGTGCACAAGCCGGTCACCGCCGGCTGGAACGGCTACGGCGACTTCCAGCACACCACCGAAGAAGCCATCCGAATGAACTGCCGCGCGGTCGCCGACCATCTCACCCGACTGGTAGACGCTGCCGACCCCGAGGTGGTGTTCGTGTCCGGCGAGGTGCGGTCACGCACAGACCTGCTTTCCACATTGCCGCAGCGGGTGGCGGTCCGGGTGTCGCAGCTGCATGCCGGACCGCGCAAAAGCGCCTTAGACGAGGAAGAGATCTGGGACCTGACATCCGCGGAGTTCACCCGGCGGCGGTACGCCGAAATCACCAATGTCGCACAACAATTTGAGGCGGAGATCGGACGCGGATCGGGGCTGGCGGCCCAAGGGTTGGCGGAGGTGTGTGCGGCTCTGCGTGACGGCGACGTCGACACGCTGATCGTCGGAGAGCTAGGCGAGGCCACCGTGGTCACCGGTAAAGCGCGTACTACGGTCGCGCGGGATGCCGACATGTTGTCCGAACTCGGCGAACCGGTAGATCGCGTGGCAAGGGCCGATGAGGCGTTGCCATTCGCCGCGATCGCGGTAGGTGCCGCATTGGTCCGTGACGACAACCGGATCGCGCCACTAGATGGGGTGGGCGCATTGCTGCGTTATGCCGCCACCAACCGACTCGGCAGCCATAGATCCTAGGATGCTGCACCGCGACGATCACATCAATCCGCCGCGGCCCCGCGGGTTGGATGTTCCTTGCGCCCGCCTACGAGCGACAAATCCCCTGCGCGCCTTGGCGCGTTGCGTTCAGGCGGGCAAGCCGGGCACCAGTTCAGGGCATCGGTCCGTGCCGCATACGGCGGACTTGCGAATCGAAGCCTGGGCACCGACCCGTGACGGCTGTATCCGGCAGGCGGTGCTGGGTACCGTCGAGAGCTTCCTCGACCTGGAATCCGCGCACGCGGTCCATACCCGGCTGCGCCGGCTGACCGCGGATCGCGACGACGATCTACTGGTCGCGGTGCTCGAGGAGGTCATTTATTTGCTGGACACCGTCGGTGAAACGCCTGTCGATCTCAGGCTGCGCGACGTTGACGGGGGTGTCGACGTCACATTCGCAACGACCGATGCGAGTACGCTAGTTCAGGTGGGTGCCGTGCCGAAGGCGGTGTCACTCAACGAACTTCGGTTCTCGCAGGGTCGCCACGGCTGGCGATGTGCGGTAACGCTCGATGTGTGAATTGAGACCTGATTCATGAAAATCGTCGAGGAGACCCCATACCGGTTCCGGATCGAACAAGAGGGCGCGATGCGGGTGCCCGGGATCGTGTTCGCGTCCAGGTCGTTGCTGCCTCGTGACGAAGGCGACATGGCCCTTGATGCAAGTGGTCAACGTGGCTACGCTGCCGGGGATTGTCCGGGCCTCGTATGCGATGCCCGATGTGCACTGGGGATATGGTTTCCCAATCGGCGGCGTGGCCGCAACCGACGTCGACAATGATGGAGTCGTTTCCCCAGGCGGTGTCGGCTTCGATATTTCGTGCGGCGTAAGACTCTTGGTCGGCGAAGGGCTGGACCGCGAGGAGCTGCAACCACGGTTGCCGGCGGTCATGGACCGGCTTGATCGCGCGATACCGCGCGGAGTGGGCACGGCGGGTGTGTGGCGACTACCCGACCGGAACACGCTGCAGGAGGTGCTCACCGGTGGTGCCCGGTTTGCGGTGGAACAGGGGCATGGCGTCGCGCTAGACCTCGAGCGGTGCGAAGACGGCGGTGTGATGACAGGAGCGGACGCGGCCAAAATCAGTGACCGGGCCCTCCAACGCGGGCTTGGGCAGATCGGCAGCCTTGGCTCGGGCAACCACTTCCTGGAAGTCCAGGCCGTGGACCGCGTCTACGATCCGGTTGCGGCCGCGCCGATGGGTCTGGCGGAAGGGACCGTCTGCGTGATGATCCACACCGGCTCACGGGGCCTGGGCCATCAGATCTGCACGGATCACGTCCGCCAGATGGAACAAGCCATGGGCCGATACGGAATCGCGGTGCCCGATCGCCAATTGGCTTGTGTGCCGGTGCACTCCCCCGATGGGCAGGCCTATCTCGCCGCGATGGCGGCGGCGGCCAACTACGGACGCGCCAACCGCCAACTGCTGACCGAGGCGACGCGTCGTGTGTTCGCTGATGCAACCGGAACACCTCTGGACCTGCTCTACGACGTGTCGCACAACCTGGCCAAGATCGAGACGCATCCGATCGACGGTCAGCTGCGCTCGGTGTGCGTGCACCGCAAGGGCGCCACCCGCTCGCTGCCGCCGCACCATCACGAGCTGCCGGCCGAACTGGCAGCGGTCGGCCAACCCGTGCTGATACCCGGGACGATGGGTACGGCGTCATATGTGCTTGCCGGGGTCACCGGCAACCCGGCGTTCTTTTCCACCGCGCATGGTGCTGGGCGGGTACTGAGCCGTCACCAGGCCGCCCGCCACACCAGCGGTGAAGCGATACGCGCCAGCCTCGCAAAACGTGGCATCATCGTCCGCGGTACCTCTCGTAGGGATATCGCCGAGGAAAAGCCGGAGGCCTACAAAGACGTCGACGAGGTCATCGAAGCCAGCCATCAGAGTGGCCTCGCGCGCAAAGTGGCTCGCCTTGTTCCCTTGGGCTGTGTCAAAGGATGAATCAACGGCGAACATTCCAGCCGTCGCGACCGCCTTCTTCAGTGGTGCAGACCCGTGACCGGCTGATGGGTACTGGCTTCGATATCCGACGACGTCAAAGCGAATAGCTGATTCGCCAAATCCGACAAGGCCCGGGCGATCGCAAGTTCGTCGCCGATCTGGGCCACCGGCTCATCGGCCGGATCGAGTCGCGCCAAACCAACACCCACCATCTGCCTGCCTGCCCAGGACAGCCGCGCCTTCGCCCGGGTGCGCTCGTCGTGTTCCTCAATCAGCACATCAATTTGGCAGGTTTTTCCAACGTGCTCGCTGTCTGTCATCGCGGCCTCCCTGTCGGATTTGCGCTTACGCCCGCCGATCTGCCCCGCTAGCTGAACGCGGTATCTATCCAATCACCACAATCGGTCGTGGAGTAGGCCAGAATTCTTTTCGCCCGACCCGGGCCCGCCTAGCACTGACAACCGCTAGATGGCCTTCAGGAGGTCTGCTTTGCCCTTGGTACGGAGTGTGTACAGAGGTGAGCCGCGCAACTGCTCAATGCGAGCCGCCATCTTGTCACCGAGCTCCTCGAGCTCGGCATCGGTGATGTGCACCGGTGTAGGAGCGGGGATCATGTCGCGTTCCTCTACGTCGGCGTGCGCCTCCAACACGGTCCGGAACACGTTCCACTCTTCTTCATACCCGGGCGCGCGCTGCGGAGTGCGCAGCAGCGTCGCGAGCTGATCAACCACCTGACGGTGCTCGGCGTGGGTACCCGTGATTGGTTTGCCGGCCGCGGAAAGGGCAGGGTAGTACAGGTCATCCTCGATGCGGAAGTGAATGTCCAGCTCGATGAGCATCTCGTCGAAAAGGACATGGCGCTCTTCGCTATTCACCGGCGCCTCGCCGACTTTGCGGCCCAGTCCTTTAAGCACGGTGTGGTGGCGCTTTAATACGTCGTAGGCATTCACTTCGTTGCTCTATTCCGTATTCGGGATCAACGAGACAACCGTAACCTCGCGCCGCGGCCCATTAATGTGAGGTAGCTGTGAATCAGCACAAAGAAGCCTGTGCAGTAGCGCGACGCTCGGCGTACCGGCACGAGTCCGACGGCCCGCATGTCCATGCGGCCGCCGGCACCAGCGCCGAGGCCCCCGCAGGATACCGGGATCTGCAGCTCCTCGTGCGGAAACAGTTGCCGCAGTTCGGGTTCGGGCAGTTCGGCGAGCGTGATGTTCGCGCCTAACGGCAACAACTATCCGTCGGCGCCCTGGGTGCCGGGCGGGCCCATATTGCCCTGGATGCCGGAGCTGCCACCCGGTGACCCACCCGCGCCGCCGGCGCCCCCGTTGCCGCCCAGCGCGAAATCGCCGCCCTGACCGCCGGTCGCGCCGGTCCCGCCGTTGCCGCCGTTGCCGCCCTGGCCGCCGAGGCCACCTTGCCCACCCGTGCCGCCTGCGCCGGTGCCGCCGGCAGCTCCTGCCCACCCGATCAGCCCGCCGGCTCCGCCGCTGCCGCCGGTGGTCCCGCCGGCGCCGCCGGTACCGCCAGTGCCACCAGCGCCCCCCACGCCGCCTGTACCGCCGCCACCGCCAATTGTCGCTCCCCCGCCGGTGGTGGTACCCGCGCCGCCGGCGCCACCGTTGCCGCCGGCACCACCGATGCCGCCGATGCCACCGGTGCCGCCGACACCGCCGGCACCCCCGCCACCACCAAGCCCGATGAGCGACCCAGCCGCCCCGCCGTTGCCGCCGACACCGCCGCTGCCACCCATACCGCCGGTACCGCCGACACCGCCGAGGCCCCCCAGACCGCCGGTGCCGCCTTCCGCGGTACCCGCACCGTCGGTGAGACCCTCTCCGCCCGCGCCGCCGACACCGCCCGCGAAGCCGGCGGCGCCACCACCACCGGTGCCGCCCGTCCCGCCGGCCCCACCGGCGCCGCCGTTGCCGATTAACATCCCGCCACGTCCACCGTTTCCACCGGCACCACCGGTGCCGCCGTTACCGCCCGCCGCGCCTAGTGCCCCGTTACCGTCACCGCCGATTCCGCCGTCACCGCCGAAAGCGTCACCTACACCCGTGTTGTGCCCCTGCCCCCCCTTGCCGCCAGCACCACCCACGCCACCGTCGACCCCTCCGGTGGCACCGTCACCCCCCTCACCCCCGGTAGCCACGCCGCCGGCGCTGCCGTCGGTCTCACCTATGCCGCCAGCGCCGCCAGCGCCGCCGGCACCGCCATCGGTACCGGCAGTACCCCCGGCTCCACCCTTACCGCCGGTGCCGTCGTTGCCGTCGAGCGACTCCCCCAGCCCGCCCTGCCCGCCGACGCCGCCAGCCTCGCCGACGCCACCGGCGGGGCCGGGACCCCCGTTCCCGCCAGTTTGATTCCCGTTGCCGCTGTTGTCGGTACCGTTCGCACCGGTGTTGGGGTTCGCAATCGAGCCGGGGTTGACCCCGTTTGTCCCGGCCAGACCGGTGCCACCCTGCCCGCCGGCACCACCGGACCCGAACCAGTTGGCATTACCGCCGTTGCCGCCCGCGCCGGGCATCCCGCCCAGGACACCCGCCACGGCCGGCCCACCCTGTCCGCCGGCACCGCCATCGCCCAACAACATCCCGCCGGCACCGCCATTACCACCGGCCGCCCCGGCCCCACCCAGACCCCCAACACCGCCATTGCCGATCAATAGCGGACCCGCACCGCCGTCACCACCGGGCGCACCGTCCCCACCAACGCCGCCACCGCCCCCGGTCCCGAAGTAGCTGGCCGCCCCTCCGACGCCGCCGGCGGCGCCAAGGCCACCGGCCCCGCCGAATCCACCATTGCCGAACACGCCGCCAACGCCACCGCTCCCGCCCACGCCGCCGGTGGTGCCCACCCCCGCCGCGGCCCCGCCAGCACCGCCGAAGCCCCCGCTGCCGATCAACCCCGTCGCCCCACCGACACCGCCAGTACCGCCGACCAAAGTGGCCCCTGCAGCCCCACCAGCCCCACCGGTCCCGCCATTACCCAGCAACCATCCACCGCGACCACCGACACCCCCGGCAGCACCGGACCCGACCAGCCCGTCCCCACCTTTACCGCCAGTCCCGCCGTTACCGATCAACCCCGCATCCCCGCCAGCACCACCTGGCTGACCCGGCGCACCCGATCCGCCATTCCCGCCGTTGCCAAGCAACAGCCCGCCCGGCCCACCGGGAGCCCCCGTCCCGTCGGCCCCGTTAGCGCCATTGCCGATCAACGGGCGCCCCAACAACGCCTGGGCGGGGGCATTTACCACGCCCAACAAATCCTGCAACGGCGCAGCACTGGTGGCCTCGGCAACTACGTATGAGCGCGCGCCGTTCGTAAGGGACTGCACGAACTGGGCGTGAAACGCCGACAGCTGCGCACCAAAAGCCTGATAGCTCTGCGCGTACGACCCGAACAAGGCCGCAACTGCCGCCGAAACCTCATCCGCGGCAGCCGCCACCACCCCCGTGGTCGGCAATGCCGCCGCCGCATTCGCCGCGTTGATCGTCGACCCAATGTTGGCCAGATCCGAAGCCGCCATCGTCAATGCTTCCGGCACCGCAATCACAAATGACATCTGCGACCTCCTGGACCGGACAACCCGCATGGTCGCCGCGGATCATCGAGCACTCGGCAGCAACAAATCCTATCCCGCCTCGCAGACGGCGGAGGCCATTTGGCCGCCGGCGCGTACTCTTCGCTACGACCGCCAGAGCCCTTGGTTAGCGACCGGATTCGACCGCCGCATGAGCCAAACTGTTACCGGTGTGGGTGTGCAGAACTGCGCAGTTAGCAAACGCCGATGCAGCGCGGTGGACCACAGCAGCCGCACACCGTACCGGCGCTGAGTGATAAACCCGACCCGGGCCCGGCGGATGCGATATCGTCTTGCGGCTATGGCGGGTATGCCAGAGGGCAAACTCATCCTCCTCAACGGCGGATCCAGCGCGGGAAAGACGTCGCTCGCCTTGGCGTTTCAGGATCTTGCCGCCGAGTGTTGGATGCACATTGGGATAGATCTGTTCTGGTTTGCGCTGCCGCCAGAGCAGCTTGACCTTGCGCGGGTGCGGCCCGAGTACTACACATGGGACAGCGCGGTCGAGGCCGACGGGCTGGAGTGGTTCACCGTGCACCCGGGCCCCATCTTGGACCTGGCCATGCATTCCCGCTACCGCGCCATCAGGGCATACCTGGACAACGGAATGAACGTCATCGCCGACGACGTGATCTGGACACGTGAGTGGCTGGTAGACGCTCTGCGGGTTTTTGAGGGCTGCCGAGTCTGGATGGTCGGGGTCCACGTATCCGACGAGGAGGGTGCCCGCCGGGAATTAGAACGCGGCGATCGCCACCCCGGGTGGAACCGAGGCAGTGCGCGCGCTGCCCACGCCGACGCCGAGTACGACTTCGAGCTGGATACCACCGCGACCCCGGTCCACGAGCTGGCCAGGGAGCTGCATGAGAGCTATCAAGCCTGCCCGTACCCCATGGCTTTCAACCGGTTACGCAAACGCTTCCTATCTTGAAATGGAGCCAAAAGTCGTGCGCAACTGGAACTTTCACTCCTGGCAAACGCTGGGGCGACCCGTCACCGCGCGCTTGGGTTCGGGTCGAATCGTCGGCCGCGCGGGTCGTGCGGAACATTGCACCCGACGCGGCGGAATCGGAGTTGAGAAGTACATGGCGGGACGCACCCGGCACCGGTCAGGCATTCTTTACCCATGGATGTGGAGGCCCTGCTGCAGTCGATCCCGCCGCTCATGGTCTACCTGGTGGTCGGCGCGGTGGTAGGGATCGAGAGCCTGGGCATCCCCCTTCCCGGCGAGATCGTGCTGGTCAGTGCCGCGGTGTTGTCGTCGCACCCCGAGCTGGCCGTCAACCCGATCGGCGTCGGCGGCGCTGCGGTGATCGGCGCCGTGGTCGGCGATTCGATCGGCTACTCGATCGGCCGCCGCTTCGGCTTACCGCTATTCGACCGGCTGGGCCGGAGGTTCCCAAAACACTTCGGCCCCGGTCATGTCGCGCTTGCTGAACGGTTGTTCAACCGATGGGGAGTCCGAGCCGTGTTCCTCGGTCGCTTCATCGCGCTGCTGCGGATATTCGCCGGACCGCTCGCTGGCGCCCTGAAGATGCCCTACCCGCGCTTCCTGGCCGCCAACGTCACAGGCGGCATCTGCTGGGCCGGCGGCACCACTGCACTGGTCTACTTCGCCGGGATGGCCGCCCAGCACTGGTTGGAACGGTTCTCCTGGATCGCGCTGGTCATCGCGGTCATCGCCGGCATTACGGCCGCGATCTTGCTGCGCGAACGCACTTCGCGCGCGATCGCCGAACTCGAGGCCGAGCACTGCCGCAAAGCCGGTACCACCGCGGCGTGACCGACCGGCTTGAATCCGGTACCCACGCTCACAGGAGCTGCAATCTAGACAGATCTCCAGTCATGTCATAAAAATGAGATCTGAAATTACTTGACAAGCTTGTCTTCGGACAGTGCGGGGCATCCGCCGCGGTGGCTGTACGCCGTCGATTAGGAGCGCACCATGGGCCTGATCACTACAGAACCACGCTCTAGTCCCCACCCGCTCAGCCCACGGCTCGTCCACGAGCTAGGCGACCCACACAGCACGCTGCGGGCAACCACTGACGGCAGCGGGGCAGCGTTGTTGATCCACGCGGGCGGCGAGATCGATGGCCGCAACGAGCATCTCTGGCGTCAATTGGTCACCGAGGCCGCCGCCGGCGTCACGGCGCCCGGACCGCTCATCGTCGACGTCACCGGGCTCGATTTCATGGGCTGCTGCGCTTTCGCCGCACTGGCCGACGAGGCACAACGATGTCGGTGCCGCGGCATCGACCTGCGTCTGGTGAGCCACCAGCCGATCGTCGCCCGGATCGCCGAAGCGGGTGGGCTGAGCCGAGTGCTGCCCATCTACCCGACCGTCGATACTGCGCTCGGCAAGGGCACGGCCGGTCCAGCCCGTTGCTGATCCCGGCCGTAAGAGCACCGAGCCGACCGCCGGTGGCCCCACCGCTAGGGCCGATCGCACCGCCGCGCGACGATGTTCGCGTCAGGCGCGCATGCGGTATCGCTTGCCTTGCAAGGTAATCCACTTCGGACATCCACGATGCAGGTCGCGATCAAGTCGGGCGCGCCGCAGCAGTCAGTGGCCGCGAGGGGCGTACATGATCACGGCTACCCCGGCCATGCAGCCAAGGGCACCGATGACATCCCACCGGTCGGGCCGGAACCCGTCCAGGGCCATGCCCCAGGCGAGCGAACCGGCGACAAACACACCACCGTAGGCGGCCAAGACCCGACCGAAATGGGCGTCCGGCTGCAATGTGGCGAAGAACCCATAGACCCCAAGCGCAATAACTCCGAGTCCCGCCCAAAGCCAACCCCGTTGCTCGCGGACGCCCTGCCATACCAGCCACGCGCCACCGATCTCCGCAACCGCCGCCAGGACGAATAGCAGGATTGACCGCACCACCATGGTTGCGAGCCTACGAGATCCGCTGCCCTGCCGCCCCCCAACCAATCGCGCACCCCAAATGCTTCCCGTCACCCGCGCTCAGCCAGACACCGGTGTTGGCTACAACTATGGTTCCCGGATCAGGCGCAGCAGTTCGGGTTGAGCACGGTACACAGCGCTTGCAGGGCTTCAGGATGTACCCGATGGAAGACGTGCATGCCCCGGCGATCGGAAATGACCAGGCCGGCCTTGCGCAGCTGGGCCAAGTGGTGGCTGACGGTGCCATCGCTGAGGCTGAGCGCCGCCGCTAGTTGGCCGCTGACCTGCTCGCCGGCCGGCAAGCTGAACAGGTAGGACATGATCTTGACTCGTGCCGGGTCGGCCAGGGCCTTCAGCCGCAGCGCCACCGCCAAGGCGTCGCCGTCGCTCATCGGCCCCGCCGCCACCGGGGCGCAGCACACGGGAGCGGAGATGTCAATCACCGGCAGCGACTTGGGCATAGGCCCACCCTGCCAGATACCTTGACATATATCAAAGAGATGTTGCACACTGGGTTCGGCGCCATTTTGATATAAGTCAAACAACTGGGAGGTGTCTACCAATGTCCCGCGTTCAGCTAGCCCTCAACGTCGACGACCTGGAGGCCGCAATCACGTTCTACTCCAGGCTGTTCAACGCCGAGCCCGCCAAACGCAAGCCCGGATACGCCAACTTCGCGATCGCCGATCCGCCGCTTAAGTTGGTGCTGCTGGAGAACCCCGGCACCGGCGGTACCCTCAACCATCTCGGTGTGGAAGTCGGCTCGAGCAACACCGTGCATGCCGAAATCGCCCGGTTGACCGAAGCCGGACTGGTCACCGAGAAGGAGATCGGCACCACGTGTTGCTTTGCCACCCAGGACAAGGTGTGGGTGACCGGCCCGGGTGGGGAACGCTGGGAGGTTTATACCGTGCTGGCCGACTCCGAGACCTTCGGCAGCGGTCCTCGGCACAACGACACCAGCGACGGCGAAGCAAGCATGTGCTGCGACGGCCAAGTCGCCGTTGGCGCAAGCGGCTAACTGTAGGCCTGACCCCGGGGTGCGTCTCCAAGCCGCGGAGCCCACCCCGGGCCACTCAATGCCCCCTAACCCGCGTAGCGCCGTTCACCGCGTGGCCGCTTGCGGACCTGATTCGATATTTGTCAATATTGATGTATGTCGAATCTGCATCCGTTACCAGAGGTGGCGAGCTGCGTAGTCGCGCCGCTGGTGCGCGAACCGCTGAATCCTCCGGCCGCGGCCGAAATGGCGGCCCGGTTCAAAGCCCTGGCCGATCCGGTGCGATTGCAGCTGCTGAGCTCGGTTGCCAGTCGCGCCGGCGGCGAGGCCTGCGTCTGCGACATTTCCGCGGGAGTCGAGGTGAGCCAGCCCACGATTTCGCATCATCTCAAGGTGCTGCGCGACGCGGGTTTGCTGACCTCGCGGCGTCGGGCCTCGTGGGTGTACTACGCCGTGGTCCCCGAGGCGCTGACCGTGTTGTCGAACCTGCTCAGCGTGCATGCCGATGCCGCACCCGCCCTGGGGGCACCGGCATGACGGAGACGGTCACCCGCACCGCCGCCCCGGCGGTGGTGGGCAAACTCTCGACGCTGGACCGCTTCTTGCCGGTGTGGATCGGGTCGGCAATGGCCGCCGGGCTACTACTGGGCCGGTGGATTCCCGGCCTGCACACCGCCCTAGAAGGGGTTCAGCTCGACGGGATTTCGCTGCCGATCGCGCTAGGCCTGCTGATCATGATGTATCCGGTGCTGGCCAAGGTGCGCTACGACCGCCTCGACACCGTCACCGGTGACCGCAAGCTGCTACTCAGCTCGCTGCTGCTGAACTGGGTACTGGGCCCGGCGTTGATGTTCGCGCTGGCTTGGCTGCTACTGGCGGATCTGCCCGAGTACCGCACCGGGCTGATCATCGTGGGCCTGGCTCGCTGCATCGCCATGGTGATCATCTGGAACGACCTGGCCTGCGGGGATCGCGAAGCCGCCGCCGTGCTCGTCGCGTTGAACTCGATCTTTCAGGTGGCCATGTTCGCCGCGCTCGGCTGGTTCTACCTGTCGGTGCTACCGGGTTGGCTGGGCCTCGAGCAGACCACCATCGCCACATCCCCGTGGCAGATCGCCAAGTCGGTGCTGATCTTCCTCGGCATCCCGCTGCTGGCCGGCTACCTGTCGCGGCGGATCGGCGAAAAGACCAAGGGCCGCAACTGGTATGAATCCCGCTTCCTGCCCAAGGTGGGACCGTGGGCGCTCTACGGTTTGCTGTTCACCATCGTGATTCTCTTTGCGCTGCAAGGAGATCAGATCACCGGCCGACCGCTGGACGTCGCACGCATTGCGCTGCCGCTGCTGGCCTACTTCGCCATCATGTGGGTAGGCGGCTACCTACTGGGGGCGGCGCTGCGGCTAGGGTATCGGCGCACCACCACGCTGGCGTTCACCGCCGCGAGCAACAACTTCGAGCTGGCCATCGCGGTGGCCATCGCCACCTACGGCGCCACCTCCGGGCAAGCCCTGGCCGGAGTCGTCGGGCCCCTGATCGAGGTACCCGTCCTGGTGGGGTTGGTCTATGTGTCCCTGGCGCTGCGCAACCGCCTCGCCGGTCCCAACGCGACCCACGATGCCGACAAACCCAGCGTCCTATTCGTCTGTGTGCACAACGCCGGACGTTCCCAGATGGCCGCCGGGCTATTGACCCACTTGGCCGGTGACCGCATCGAAGTCCGTTCGGCCGGAACCGAGCCCGCCGGTCAGGTCAATCCGACGGCTGTGGCCGCGATGGCCGAAATGGGCATCGATATCACCGCCAATGCCCCCACATTGCTCACCGGCGGGCAGGTCCAGTCCAGCGACGTCGTCATCACGATGGGCTGCGGCGATGCCTGCCCTTACTTCCCGGGTGTCTCCTACCGCAACTGGAAACTACCCGATCCCGCCGGCCAGCCCCTCGACGTTGTGCGCATGATCCGCGACGACATCGCAGACCGCGTCCAAGCCCTGATCGCCGAGCTGCTGGCCACCGCCAAGACCAGATAGCGTGTGCCACGCTCGGTGCTGCGCCGATACGTGAGGTCCCGGCTGGGATCGGATTTTCCGCGTGTACGGCGGCTAGGCACCAGCGGATCGCATTTGTACTGGTTAGAGACTTGCCGAGTGGCCGCATTAGCCTGCGTGGAGCGCTTGGTCAAAAAGCTCGGCCCTGTTCGGCCCTATGGGTTCCTGTTGATCTGCCCTGTTCGTAGTCTCGACAAAGCGGCTGCCCGAGATCGCGTGCGACGATATCGGGAGCGGCTGCGGCAACGAGGTCTGCGGCCGATACAGATCTGGGTTCCCGATGTGAACGCACCCGAATTTGTCGGCGAAGCACACCGTCCGTCGGCGCTCGTCGCGGCCCGCGAATACGAGGACGACGATCAAGCCTTCGTCGATGCGGTATCGGTCGACTGGGACGACGCCACCTGACGTGCGGCGCGGCGACATCCACACCGCGGCGGCGCGTGGTGCCTACACCGGCAAGCCACGCCGGTCGCGGTCATCCAGAATGACCGGTTCGATTCGACGGCCTCGGTTACCGTCGTGCCGTTTACCACGCGTGATGTCCAGGCATCCCTGATGCGAATCCCGGCCCCAGCGTCCAACACCACCGGGCTGACCGAGACCAGTCGCCTGACGGTCGACAAGGTGACAACATCCCCCGCACCAGCCTGACGCGGCAGGTTGGTCGGTTATCGGCCAAAAACATGGTCAGGCTCGACCGTGCATTGCTGGTTTTCCTGGCCGGCTGACAATTGCGCCACCTGGTCATCAGAACTGATCGGGCGGGGAAACGAAACGGGGCTCCCAGCGGAGGTCATGAGTTGGCGCGCCGGTTTCGCCGCGATCTCTCCGAACTTGACCGCTAAACCTCGGGGCAGAAGTCATGAACAAGCCCGTTAGGAGGCGTTTGAGGCCGTAAATGTTGATGAGGGCGGGGAAAGTGTCGTCATGGCCGTCGCGCTGAATTCACCACGCCCCCACGACGGAGCTCGTGGGCACCCAGCATTCACTGCTTACCACTACGATCTCGCTCACGAGGTTCGAGCAGCCACTGTCGCCTGCCGCCAACGAATAATGCTCCCTGACCCAGTGGTCCCGGCTGGGATCGAACCAGCGACCTTCCGCGTGTGAAGCGGACGCTCTCCCACTGAGCCACGGGACCGGCGCCGAGGAGATGAACGAGGTCGAAGATTAGCACGTGCAAGACATCGTCAGCAGCAGTCTACGTGCGCTTCACATAGGGGCTGCGATAGCCTAGAGCCGCAACGTACCAAGAGATTTGTGTGGGCCCGCTCACCTCGACTATCGTCGTGCTTCGCACCGGGCGACGATCTCGTTCGTTGCGCGCGGATGTAGCGCAGTTGGTAGCGCATCACCTTGCCAAGGTGAGGGTCGCGGGTTCGAATCCCGTCATCCGCTCGAAGGTGCTAGTGGCATCAAATCCCAGCGGTGGAGTGGCCGAGTGGTGAGGCAACGGCCTGCAAAGCCGTGCACACGGGTTCGATTCCCGTCTCCACCTCCAGGTTCAACCCCCAGCGCGATTAGCTCAGCGGGAGAGCGCTTCCCTGACACGGAAGAGGTCACTGGTTCAATCCCAGTATCGCGCACCAGTGTTCGAGCAGGTCAGGCCTGGTTTTTACCGGGCCTTCGCCGTTTCCGCGCAATAAACGCGCAATAGTGCCGCCGCTGGGTGCGCCCCACGGAGGAGTTTGCTAAATGACCACCACGCCCCGACAACCCCTGTTCTGCGCCCACGCCGACACCAACGGCGACCCGGGCCGCTGCGCCTGCGGCCAGCAGCTCGCCGACGTCGGCCCGGCCACCCCGCCACCGCCCTGGTGCGAACCGGGCACCGAACCCATCTGGGAGCAGCTCACCGAACGATACGGCGGCGTCACAATCTGCCAGTGGACACGATATTTTCCGGCCGGCGACCCGGTGGCTGCCGACGTGTGGATCGCCGCCGACGATCGTGTCGTTGACGGCCGGGTGCTGCGCACCCAACCGGCGATTCACTACACGGAACCGCCCGTGTTGGGGATCGGCCCGGCGGCGGCCCGCCGGCTGGCCGCTGAGCTGCTCAACGCCGCCGACACCCTCGACGACGGCCGCCGGCAGCTAGACGACCTCGGCGAACACCGGCGGTGAACACCGCGACCCGGGTCCGGCTGGCCCGCAAACGCGCCGACCGGCTCAATCTGAAACTAATCAAGAACGGCCACCACTTCAGGTTGCGTGACGCCGACGAGATCACGCTGGCGGTCGGGCACCTAGGGGTGGTGGAAGCCTTCCTGGCGGCGGCCAAGTCGCAAAACAAGCCGCCCGGTCCGCCGCCGAGCCTCCACGCCCCGCCATCCTGGCGGCGCGACATCGACGACTACCTGCTCAACCTGAACGCCGCCGGTCAACGCCCAGCGACGATCCGGCTACGCAAGACGGTGCTGTGCGCAGCCGCCCACGGCCTCGGCCGCCCACCCGCCGACGTCACCGCCGAACACCTCCTGGACTGGCTAGGCAAACAGCAGCACCTCTCCCCAGAGGGCCGCAAAACCTATCGCAGCACGTTGCGGGGCTTCTTCGTGTGGGCCTACGAAATGGACCGGGTGCGCGACTATGTCGCAGACTCCCTGCCTAAGGTGCGCTGCCCGAAACAGCCGCCCCGCCCGGCCGGCGACGACGTCTGGCAAGCGGCGCTGGCCAAGGCCGACCGTCGAATCGAGCTGATGATCCGCCTAGCCGGTGAGGCCGGGCTGCGACGCGCCGAAGCCGCCCAGGCGCACACCGGCGACTTGATGGACGGCGGGCTTCTCCTCGTTCACGGCAAAGGTGGTAAACGCCGTATTGTGCCGATCAGCGACTACTTGGCCGCGCTCATCCGCGACACCCCGCACGGCTACCTGTTCCCCAACGGCACCGGCGGCCACCTCACCGCCGAACACGTGGGAAAACTCGTCTCCCGGGCATTACCCGGTGACGCGACCATGCACACCCTGCGGCACCGATACGCCACCCGCGCCTACCGCGGCTCCCACAACTTGCGAGCTGTACAACAACTTCTCGGTCACGCCTCGATCGTGACAACAGAACGCTACACAGCGCTGTGCGACGACGAGGTGCGCGCCGCAGCAGCAGCCGCATGGTGAGTCGCCCTGGCGTTTGCTGCAGCCGATCGGCGTCACCCCCGACAGGCGGCTCGTATTCGGCCAGCGGCGGCTCGAGGCTGCACGGCTGCTCGGATGGGAGCGCATCCCGGTGCACGTGTGCCACACGATCGCCGACGTGGTCGACCGGGCCAAAGCCGAACGCTCCGAAAACACGCTTCGCAAGGATTTCACCCCCTCGGAGCTGCTCGCCGCTGGTCGCCGGATCGCCGAGCTGGAACGGCCGAAAGCCAAACAGCGGCAACGCGAAGGCGGCGACCATGGCCGCCAGGCTCGATATTCTGGCTTAGGCTCCATGGAGCCTAAGCCAGAATCAGAGCGCGATGCCCACAAAGCCGACACTGCCATCAGCGAAGCCCTCGGCATCTCCCGCGGCCACTACCAGCGGCTCAAACGAATCGACAACGCAACCCGCAGCGAAGCTGGCTACCGGGATGGTTTAAACGGTTGGAGCGGCTGACCGCCGGTGCCCGGGATGGGCCCCGGCGGCAACTTGTCCAACGGGCGACGCTCACGTCCACGCTTGCGCAGCTCATCTTCGGCGGCCTTGCGTGCCTGCTCAGCCTGGCGGCGCCAAGCCTCATAGCGACGCCGAATCTCCCTCTCAATCGCGCGCTGCACACCCATCCGGAACTGATCCTGGACACGCTGCTGCTGCCGAACCCAACGCTCAAGCTCACGCCGGTAGTCGTTGACTGATCTCGCCACCCAAAATCACCCCTCTTGACCCTCGTGGTTCTCTTTTTGGCGGCGTGGGCGACCCGGCACCCCTAAGTCTCCGGGCCGTGCGGGCCGCTGGGAGCCGAAAGGTTGCTAAAGTTCTCCCTTTTTGCCCGCACGACCCGAAAAGGGCCGCCCACGCCTGGCACCTACGCGGTGGTCTGCACCTTCAGCACGCGGAACGCATTGTCCACCAGCACATCAGAACCGACTCGGAACCAGCAGAAGAATCCGCGCTGTCCGGTCGGTCGGCGGTTGCCGCCGAACACGTGCGGCACCAGCTCCACCGTCGACCCGACCCGGTCGGTGATGATGAACTGCTTCCAGTCGCCAAGCACCAGCGGGTAATTGGTGGCGGTCACCGCCGCGTCCACGGTGTCCATGTTCGACACCTCCCAGATGTGTTTCCCGGCCAGCATCGGCGGGCTGGCGTGCAGCGATGGGAATTTCAGCGCCCCATTCGCGGTTTCCGCCTGGCGCAGCACGTTGATGGTGGACAAGTTCGCCGCGAACGCGCTGTTGGATTGAAAGCGCGGCGGCAACGCCGACTGCAGCGCGTAAACGTCGGCGGCTACAACGGCTTCCGTCCCCGCGCCGGTGACGGTGTAGTCCGCGGTGCCGGTCAGTGCGGAGACGAATCCGGTGGGCTCGCCGTTGCCGGAGCCGCTGACGAACGCCGCCGCCTGCAGCTGCTCAACCGAATCCGCTAGGACGCGGCCCACCTCTGCGACGAATCCGGCGGCGTCACCCTCAATCTCGAGACTGAACGGAATCCAGCAGGAGCCACGGTAGCTCGGCACCGCCGGCTGGGCCAGCGTTGGCGAATCGTCGGACACCTCCTGGGCTTCGGAGTACCAATGAGCCTCGGCGCCTTCGGAGGTCACGCCCCGCCAAACCTCGGAGGTCGTTTGCACCACCCTCGCCACCTGCCGGATCGGATTCGTTGAACCATCACCCGACAGCAGAATCGCCGGATCCAGCGCCGCCGGGATCAAAAACCCGCCGGCGGTGTCCACCAAGCCCATTGCTCGCTGCTCGGCGGCCACCGCGGCCGCCTCACGCCACGCGGCCGCTTCCCGGTCGGTCCAGGTCGTGTGCCCCGCAACAGGGTTCGAAACCCTCTTGACGAACGCCCCCAGGTAGTCGCGGTTGCCGGTGGCCGCCAGCCAGCGCTGCGCCCACGACGTCGACTGCGGCGGCCCGGTGCGGCACAAGGTTTCCGCGGCTTCCGCCGCCCGCGACGACATCAGGCCATCGCGCACACAAACGTCCAGTGTGCGAAACGCGGTGTCGCGCAACGAGTTGCCCGGCGGCGCGTCGCCGTCGTCGCCGCCGGTGGGAGCACCGGGCACCACCCTCAGCTCACCGGCCCGGCAGCGGCGCAGCGCCTCCTCGGCTTCGCGGCCGCGGCGGCGCTGCTCCGCCCGCAGTTCCTCGGCGTGGCGTGTCAGCGCCTGAAAACGTTGCGCCACATCACCGGTCAGGTCGCCCTCGACGGAGTCGAGGAGCTGTTTTGCCGCGGAACGGGTTTCGTCGAGGCTGAGCTGTTTGATGTCGCCATCGTCAGCGAAATGTTGTTCATTAGTCATGAGAGAGTTACCAATCCATCAGGGCTAACCTGGCTTCGGCTAGCGAACGGGAAACGACTGCAAGCGATTCCGCGCGCACACCGGCGATCTGCGCGCCCAGATAGGCCGGAACGCCGGTCAAGGAGACCTCCAACAGCGCCGCCTCGACCCGCACGATCACATCCCCTTCCCGGCGGTCCCGGATCGGCCGGAAACCCACCGAAAACGCGTCCACCACACCAGCTTTCACATTCGCCAGGGCCTCGTCGCCGTCCGGGGTGTTCGCAAGCTCGAACGCCCCGAACAAGCCGTGAGGCTCCTCACGCAGCTCGACGGCCCGGCCAACCGGGTAGCGGGTTCGAGCGTCGTGGGAGACCAGCAGCTTCACCTTGTGGCCGCGCTCAGCGATGGAGCGCCGAAAAGCGCCAGGAGCGAACATTTCCCGGAACTCGCCGTCGAGGTCGCGGACGGTGGTCACCTCGCCATAAGGCACGATGACGCCGTACACGGTGCGGCCCTCACCAGGCCGCAGCTCGGCCGTGCGGAAAAGGATGCTACTCAAAATTCGGCCACCGCCTAGCAGACGCAAGAAACGCGCGGAATCGCTTGTGGCGCATGGCGGCCGCTATCCGGGTTCCAGCCGCCCCGCGGCGACTGCCCGGCGTCGGCGGATGCCGAGATGCCAAACTCGATTGTATCACACACAAAAGGTCATCACCGGTCTGGGGCGAACGGGTTGAACTCGTCGTCGTCGGGGTCCCCCGCCGCCGCCAGCACAGCAGCCAAATTCGCCTCAGCGCTTGGCGTGCACCCCAATTCGCGCGCGAGCACCAAAACGTCCCTCGTCGCGGCCCGGGCCGCGGCCACGGCAGGATGCACCGTCACCCGTCGGCTGCGGGCGTTCGTCGCGATGAAACCCTGTTCACGGTAGGCTGTTACAGCCTGCATGAGCTGATCCCAGGCGACGCAGAAGGAGGTCAGCACCCCAAGGTCGGACTCCTTCAGCAGGTTTAATGCCGCAAGCTCGGGAACGACGCGCCCCCACATGTCTTTAGCGCCTGGCGGCAACCAATCCGGGCATTCCGGCGCAACACGCTCGAACGCCGCCGGTGGTGTAACCCGCCGGCCGCCAGAATCACGGCCCGGCGAGCGGCCGCCGAGGAGTTTCAACTGCGCCGGCGCCGGCGCGGGACCACGCCTACCCATTTTCAACACCACCCTCCTCTTTCCGGGTTTCGGGTCGCGAATGCCATGATGCCAAAAAACGCCCCATAAAACTTGAGCGCGCACACGCTCTCCCACCGTGGCGGTGTCCGGTCGGGCGGTTGCTGGCGATGGCAACCCACCCCCCCTACCTGCGGGTTTCGGGTTTTCACTGTTTGCTGTCGGGTTCGTCGGGGAAGTGATACGGATGCCAGCCGAGCTTCATCCCCGCCTCAAGCCGGCGCTGCTCATCGTCGAGATGCATCGACAACAGCGCCAGTTCGGCTGTGTCGTCGTCGATTTCGTGTGATGTCGCCACCATCTCGGCGTACGCTCGGCGGATAGCCTCGAGGTCGCGCTGCCGTTGGGCGCGGCGCTGCTCGGCGGACGGAACGTCGGCCGGCCAACCATGTTGCCGCCCAACGCGATTCCGACGCGGGGCGTTGAGCCCTGCGGCGATGGCTGGCTGGCGTTTAGTGCGCTTGTGGGTCAATGATGGGCTCCTTTCTCCCTGGAAAATGATGTGATCGACGGTGTTCCGGGTGTCCGACAGTCGGGTTCTCTCGGCGGGCTCACGGCGGATCACCCCGGTCGACGGCCGCCGCCGCGGCGGCCGTCGCGGCGAACAAAACGGCCGCGACGCCGTGCGACTCCGCCACAGCGCGGACCAACGCTCGCGCAAGCTCGACGGCCGCGGTCCGCCATGCGCCCGCGGCGTCGCCGGCCAGCGCGGCGGCCGAAGCCTCGACTGGCGGGCCGCCGACAAGCTCGTCCGCGGCGGCCAGCAACGTCCGAGCAGCCAACGCGTGGCCGCTCATCGGGCGCCGTCCCGAGCGCTAGCCGCCGCTCGACCTCGGCAGGGCCGGCATTTGCCGGCGGCCTTGGCCTCAGTACTGAGGAGCTTGTTGGGGCATCCCGGCCCGGAGCACAGCGGCGCGTCGCCGTTGGGGTGCCCGTTGGGCGCCGGCGGCTCGTACGGCAAGTCGCCCGCCTCCGGGAGATCGGTTGCATCGGTTGCGCCGGTTGCATCACCGGGATCGCCAACCGGCGGTGAAACCGCGGAAACCGCGGAAACCGATAAATCTCGTTCCTCGGGGGTTTCGTCGTCGGCAGAGAGATACCGGGACCACGCATCCTCGAACTGGGTCCGCGAATACCCTTTGTAGGGTGGTTCGCCACCACTGTGCTGGAACTTCGGCCCGATGCCGTATCTGCCGAGCCGGGTCGCGAGGCCGCGCGCGTCGAGCGGGTCGCCGCGGCGGATGGAGCCCCACGGTCCCTCCTCCATCCGGTTCAGTCCGGTCAGGATGTCGCTGGTGCGCATCCGGTCCCGGTCGCTGAAGACTCGACGGATATCCCGCAGCAGCAGCACGCCTATGCTGGGCTTGGCTCCTCGATTTGCGGTTGCATCCGTTTCTGCGGTTGCACGGGCGGTTTTGGGCCAGTGCCCGCCCGCGGTGTCAGCAACCGCAACCAGGGACTCCCAGACGTCGGCGCGCCGGTCGGTCACCCCGTCCGGCATCGCCGGCCAACCGCTTTCCAGCGGGTTAATGGCGGCCGCCCAGTTCGCCAACCGGTCGTGCAGCTTCTCGGCCTCGGGGCCGTTGACGCGGGGGCGCCACGGCTCCACGGGTTCGGTTGGTGCCCTCCTGCGCATCCTCACCACGATCGACCGAGACATGATGGTGTCGGGCAGGTCGTCGAGGCCGGCCAAGGCGACCGCACAGTACGCTGGCAGTTCCTCGGTCTCAACGATCTTGCCGCGGATGACGCAGCGGCCCGCGACGGCTCCCTTGCGGTGGCCGGCGTTGATCACGCCGCGAATTTCCTCGTGTTCTTTAGCTTTCGGGCCAAACAGGGTGTCACACTCGTCGTACAGGACGGTCGGCCGCCCGACCGGATCGGCCACCCGACGGAACAGGTAGGCCGGTGTGCAGTTGATGGCATGCACCGGCCGGGGCACTAGCGGTTCCGTGACTTCGAGTGCGCGGCTCTTGCCAGAGCCGGGTTCCGGTGACAAAAAAGCGATTCGGGGCGTTGAGTCCCACGCCTCCATAAACCAGCAATGCGCAATCCAGAGGGTGTGCGCGATCAGTTCATGGTCGCTTGGATAGACTACGAACCGCCGCAAGAATGCCCTAATGTCGTCGAGCAATTCGGCGCCGACCGGCGGCATCGGCTGGCCGTCCTCGTCACACCAGATCGGGTCGGGATAGTCACGGCCGTAGGGGATGTCAGCCATCTCAGACCACCACCCGCCGAATGTAGGCGTCACGCCGACGCTGGATCTCCCGAGAGACCGCCGGCCAGTCGGCGGCGGCGGATACGTCACGTGATGCCTCGGCCGACGCGGCCTGGCACGTCTCCACCCGGAGTGCCCAATGCCGAGCAGCGTCGCAGATCGCGGCCCATTTGACCGGGTCGGTGTCGTCGAGGTCGCACCACGCCGGGGTGCCGGCCATCGGCCATTCCACGGCGGCGGCCAGGGTCGGTGCGACATACTCGTGCACCGACCACCACGACACGGCGCGGGACGCGGTAGGATCGGTGCTAGACGGTGTGGCGACTGTCGCGGGTGCCCGGTCCTCTGTGGCCGGGCATCGTCGCGTCGGCGGCGACCCGCCGACGGCGGTCATGCGGCACCACCGAACGGGTGCATGGCGCCGTCGACCTCATCGCGGCGCAGACGGACGAGGCGGGTGCCGGAGCGGTATCCGCGTAGGCGGCCGTCGGCGATCATCTGGCGGACCGTGCGGTCGGTGACCGCTAGATATTCGGCGGCCTCACTGATCGTGATGTACCGCCGTGACAACGGGGGAGCGTCTGCCATGCCGGGCCTTTCGGTCTCGTGAGAGACCGTCCACCCGAGACTCGGCGACGGGAACGCGCACATGCGCGCACCGGAAAATTTACCCGCCTAGCTGGCTCAAGCGCAAGCATAATGCGCTGAACGGAATTACGTGTCGCGCCTCTGCTATTGATGGATCGTCAGCGTCGGGGATGGTCGACGTTCTCAGCTCGTGAAGCTTCGCCCCGAAACCGTCGAGGATCGCCGCGGCGGTCATCTCGGATATCGGCGCATACTTTCGGCATGCCCGGCATTCGAGTTTCCACTCGATATGGCGGCCCCACTGTGTTTCGGTGAAGCGGGTGTTCGACCGCATCTGTATGTGCCCGCCGGCGGGTCGTTCGTCGTCGATCCAGGCGATGATGAGCGCTCCCGGTTCGTCGTCGCAGTTGCACATAACTACGTACTTAACCGCATCGGCCATCATCACATCTCCTGGTTCTCGGCCAGTTTGCTTAACAGTGCGGCGATTTCGCGGTCCCGGCCCTTGGCGGCGTGCTGGTAGCGGAGTGCGGCGCCGGCTGTGCTGTGTCCTAGCCGCTGCATCAGTTCGGCCAGTGTGGCGCCGGTGGATGCAGCCAACACGGCGCCGGAGTGTCGAAGGTCGTGCACCCGTAAGTCTGGTCGGCCGGCGGCTTTTCGGGCCTTGTAGAACATGCGGTACAGCGCCGAGGGTGCTAGGTGACGGTTGGGGTCGTTGACCGATGGGAACAGCAGGGACTCCCGGCCGGGGTTGACGTGTTTGTGAAGGTGGTCTTCGATGGCGGGTATCAGATGTGGCGGGATACTTATGTCGCGCACTCCCGCATCGCTTTTCGGTGTCGTCACCTTGAAGCCTTCGCCCACCCGAACGACAGCCCGCCGCACCCGCGCAACCTCGCCGTGCAGGTCGATGTCTTTGCGGCGTAATTCGGTCAGCTCGCCGTAGCGCATGGCCAGCCATGCCGCCATCAGCACGAACGCCTGGTAGGGGTCGGGCATGGCTTTGGTGATGGTTTCCAGCTCGTCGAGGGTGGCGGGCCTGATCTTGTGGACGCGGCGGGCGGTGGACGCGCCTGAGATGCGGCAGGGGTTGGAGTCGATCAGGTCGTCGGCCAAGGCGGTCTGCATGATTGCGCGCAGCAAGCTGTAGGAGTGTGCCCGCATGGTCGGTGTGCCCACGGCGGTGGTGGCGTACCAGCGGCGCACGGCGGCCGGGGTGATGTCGCGTAGGTCGGTGTCAGCGAAGGTGGCCAGGATGTGGTTGTCCAGCAGTTTGCGATAGTGGGCGCGGGTGCGGTCCTTGATTCCACGCTGCTTCAGCCATCCTTCGGCGTACTCACCGAATGGGGCTCCGGGGCGGTCTTCCTGACCCGATGCCGGGGACCATAGTTGTCGGTCGATTTCGCGGCGGCGGTCGGTGAGCCATGCTTCGGCGTCGATCTTGGCGTTGAAGGTTTTGGGGGCGATGTACACGCGGCCGTCGGGGCCGGTGTAGCTGGCTTGCCAGCGGCCGGAGTTGAACTGTCGGATGCGACCGAATTTGCGTCTCTGACGCTTGCCGGTTTGCGTCAC

Protein sequences of DBSCAN-SWA_1

>NC_020559|2929429:2967701|2965931_2966192_-|WP_003899418.1|DBSCAN-SWA
MCAFPSPSLGWTVSHETERPGMADAPPLSRRYITISEAAEYLAVTDRTVRQMIADGRLRGYRSGTRLVRLRRDEVDGAMHPFGGAA
>NC_020559|2929429:2967701|2929429_2931508_-|WP_003413486.1|tRNA|DBSCAN-SWA
MSAPAQPAPGVDGGDPSQARIRVPAGTTAATAVGEAGLPRRGTPDAIVVVRDADGNLRDLSWVPDVDTDITPVAANTDDGRSVIRHSTAHVLAQAVQELFPQAKLGIGPPITDGFYYDFDVPEPFTPEDLAALEKRMRQIVKEGQLFDRRVYESTEQARAELANEPYKLELVDDKSGDAEIMEVGGDELTAYDNLNPRTRERVWGDLCRGPHIPTTKHIPAFKLTRSSAAYWRGDQKNASLQRIYGTAWESQEALDRHLEFIEEAQRRDHRKLGVELDLFSFPDEIGSGLAVFHPKGGIVRRELEDYSRRKHTEAGYQFVNSPHITKAQLFHTSGHLDWYADGMFPPMHIDAEYNADGSLRKPGQDYYLKPMNCPMHCLIFRARGRSYRELPLRLFEFGTVYRYEKSGVVHGLTRVRGLTMDDAHIFCTRDQMRDELRSLLRFVLDLLADYGLTDFYLELSTKDPEKFVGAEEVWEEATTVLAEVGAESGLELVPDPGGAAFYGPKISVQVKDALGRTWQMSTIQLDFNFPERFGLEYTAADGTRHRPVMIHRALFGSIERFFGILTEHYAGAFPAWLAPVQVVGIPVADEHVAYLEEVATQLKSHGVRAEVDASDDRMAKKIVHHTNHKVPFMVLAGDRDVAAGAVSFRFGDRTQINGVARDDAVAAIVAWIADRENAVPTAELVKVAGRE
>NC_020559|2929429:2967701|2945812_2947111_+|WP_010924557.1|DBSCAN-SWA
MQVVNVATLPGIVRASYAMPDVHWGYGFPIGGVAATDVDNDGVVSPGGVGFDISCGVRLLVGEGLDREELQPRLPAVMDRLDRAIPRGVGTAGVWRLPDRNTLQEVLTGGARFAVEQGHGVALDLERCEDGGVMTGADAAKISDRALQRGLGQIGSLGSGNHFLEVQAVDRVYDPVAAAPMGLAEGTVCVMIHTGSRGLGHQICTDHVRQMEQAMGRYGIAVPDRQLACVPVHSPDGQAYLAAMAAAANYGRANRQLLTEATRRVFADATGTPLDLLYDVSHNLAKIETHPIDGQLRSVCVHRKGATRSLPPHHHELPAELAAVGQPVLIPGTMGTASYVLAGVTGNPAFFSTAHGAGRVLSRHQAARHTSGEAIRASLAKRGIIVRGTSRRDIAEEKPEAYKDVDEVIEASHQSGLARKVARLVPLGCVKG
>NC_020559|2929429:2967701|2934087_2934528_-|WP_003413574.1|DBSCAN-SWA
MSIRPTTSPALADQLKDPAYSAYVLLRTLFTVAPILFGLDKFFNLLTHPQHWNMYLAGWINDLVPGTADQCMYLVGAIEIVAGVLVAVAPRIGAWVVAAWLAGIILNLVTGPGFYDIALRDFGLLVGAIALARLAQGVHSGGIGRP
>NC_020559|2929429:2967701|2953266_2953599_-|WP_003413663.1|DBSCAN-SWA
MVVRSILLFVLAAVAEIGGAWLVWQGVREQRGWLWAGLGVIALGVYGFFATLQPDAHFGRVLAAYGGVFVAGSLAWGMALDGFRPDRWDVIGALGCMAGVAVIMYAPRGH
>NC_020559|2929429:2967701|2937833_2938727_+|WP_003413592.1|DBSCAN-SWA
MSSGNSSLGIIVGIDDSPAAQVAVRWAARDAELRKIPLTLVHAVSPEVATWLEVPLPPGVLRWQQDHGRHLIDDALKVVEQASLRAGPPTVHSEIVPAAAVPTLVDMSKDAVLMVVGCLGSGRWPGRLLGSVSSGLLRHAHCPVVIIHDEDSVMPHPQQAPVLVGVDGSSASELATAIAFDEASRRNVDLVALHAWSDVDVSEWPGIDWPATQSMAEQVLAERLAGWQERYPNVAITRVVVRDQPARQLVQRSEEAQLVVVGSRGRGGYAGMLVGSVGETVAQLARTPVIVARESLT
>NC_020559|2929429:2967701|2935336_2935690_-|WP_003413583.1|DBSCAN-SWA
MESISLTSLAAEKLAEAQQTHSGRAAHTIHGGHTHELRQTVLALLAGHDLSEHDSPGEATLQVLQGHVCLTAGEDAWNGRAGDYVAIPPTRHALHAVEDSVIMLTVLKSLPDAHSGS
>NC_020559|2929429:2967701|2935702_2936128_-|WP_003413586.1|DBSCAN-SWA
MSAGPAIEVAVAFVWLGMVVAISFLEAPLKFRAAGVTLQIGLGIGRLVFRALNTVEVGFALVILAIVVVGSTPARIAAAFSVALAALAVQLIAVRPRLTRRSNQVLAGLQAPRSRGHHIYVGLEIVKVVALLVAGILLLNG
>NC_020559|2929429:2967701|2958363_2958795_+|WP_003899409.1|DBSCAN-SWA
MTTTPRQPLFCAHADTNGDPGRCACGQQLADVGPATPPPPWCEPGTEPIWEQLTERYGGVTICQWTRYFPAGDPVAADVWIAADDRVVDGRVLRTQPAIHYTEPPVLGIGPAAARRLAAELLNAADTLDDGRRQLDDLGEHRR
>NC_020559|2929429:2967701|2948087_2948342_-|WP_003908019.1|DBSCAN-SWA
MPLGANITLAELPEPELRQLFPHEELQIPVSCGGLGAGAGGRMDMRAVGLVPVRRASRYCTGFFVLIHSYLTLMGRGARLRLSR
>NC_020559|2929429:2967701|2966208_2966571_-|WP_003900543.1|DBSCAN-SWA
MADAVKYVVMCNCDDEPGALIIAWIDDERPAGGHIQMRSNTRFTETQWGRHIEWKLECRACRKYAPISEMTAAAILDGFGAKLHELRTSTIPDADDPSIAEARHVIPFSALCLRLSQLGG
>NC_020559|2929429:2967701|2960255_2960507_+|WP_003908028.1|DBSCAN-SWA
MERLTAGARDGPRRQLVQRATLTSTLAQLIFGGLACLLSLAAPSLIATPNLPLNRALHTHPELILDTLLLPNPTLKLTPVVVD
>NC_020559|2929429:2967701|2939562_2940744_-|WP_003899401.1|protease|DBSCAN-SWA
MRDAIPLGRIAGFVVNVHWSVLVILWLFTWSLATMLPGTVGGYPAVVYWLLGAGGAVMLLASLLAHELAHAVVARRAGVSVESVTLWLFGGVTALGGEAKTPKAAFRIAFAGPATSLALSATFGALAITLAGVRTPAIVISVAWWLATVNLLLGLFNLLPGAPLDGGRLVRAYLWRRHGDSVRAGIGAARAGRVVALVLIALGLAEFVAGGLVGGVWLAFIGWFIFAAAREEETRISTQQLFAGVRVADAMTAQPHTAPGWINVEDFIQRYVLGERHSAYPVADRDGSITGLVALRQLRDVAPSRRSTTSVGDIALPLHSVPTARPQEPLTALLERMAPLGPRSRALVTEGSAVVGIVTPSDVARLIDVYRLAQPEPTFTTSPQDADRFSDAG
>NC_020559|2929429:2967701|2950710_2950953_+|WP_003899405.1|DBSCAN-SWA
MVAADHRALGSNKSYPASQTAEAIWPPARTLRYDRQSPWLATGFDRRMSQTVTGVGVQNCAVSKRRCSAVDHSSRTPYRR
>NC_020559|2929429:2967701|2953718_2954078_-|WP_015456416.1|DBSCAN-SWA
MPKSLPVIDISAPVCCAPVAAGPMSDGDALAVALRLKALADPARVKIMSYLFSLPAGEQVSGQLAAALSLSDGTVSHHLAQLRKAGLVISDRRGMHVFHRVHPEALQALCTVLNPNCCA
>NC_020559|2929429:2967701|2941747_2942989_-|WP_003899402.1|DBSCAN-SWA
MASSASDGTHERSAFRLSPPVLSGAMGPFMHTGLYVAQSWRDYLGQQPDKLPIARPTIALAAQAFRDEIVLLGLKARRPVSNHRVFERISQEVAAGLEFYGNRGWLEKPSGFFAQPPPLTEVAVRKVKDRRRSFYRIFFDSGFTPHPGEPGSQRWLSYTANNREYALLLRHPEPRPWLVCVHGTEMGRAPLDLAVFRAWKLHDELGLNIVMPVLPMHGPRGQGLPKGAVFPGEDVLDDVHGTAQAVWDIRRLLSWIRSQEEESLIGLNGLSLGGYIASLVASLEEGLACAILGVPVADLIELLGRHCGLRHKDPRRHTVKMAEPIGRMISPLSLTPLVPMPGRFIYAGIADRLVHPREQVTRLWEHWGKPEIVWYPGGHTGFFQSRPVRRFVQAALEQSGLLDAPRTQRDRSA
>NC_020559|2929429:2967701|2964113_2965541_-|WP_003899416.1|DBSCAN-SWA
MADIPYGRDYPDPIWCDEDGQPMPPVGAELLDDIRAFLRRFVVYPSDHELIAHTLWIAHCWFMEAWDSTPRIAFLSPEPGSGKSRALEVTEPLVPRPVHAINCTPAYLFRRVADPVGRPTVLYDECDTLFGPKAKEHEEIRGVINAGHRKGAVAGRCVIRGKIVETEELPAYCAVALAGLDDLPDTIMSRSIVVRMRRRAPTEPVEPWRPRVNGPEAEKLHDRLANWAAAINPLESGWPAMPDGVTDRRADVWESLVAVADTAGGHWPKTARATAETDATANRGAKPSIGVLLLRDIRRVFSDRDRMRTSDILTGLNRMEEGPWGSIRRGDPLDARGLATRLGRYGIGPKFQHSGGEPPYKGYSRTQFEDAWSRYLSADDETPEERDLSVSAVSAVSPPVGDPGDATGATDATDLPEAGDLPYEPPAPNGHPNGDAPLCSGPGCPNKLLSTEAKAAGKCRPCRGRAAASARDGAR
>NC_020559|2929429:2967701|2950953_2951631_+|WP_003899406.1|DBSCAN-SWA
MINPTRARRMRYRLAAMAGMPEGKLILLNGGSSAGKTSLALAFQDLAAECWMHIGIDLFWFALPPEQLDLARVRPEYYTWDSAVEADGLEWFTVHPGPILDLAMHSRYRAIRAYLDNGMNVIADDVIWTREWLVDALRVFEGCRVWMVGVHVSDEEGARRELERGDRHPGWNRGSARAAHADAEYDFELDTTATPVHELARELHESYQACPYPMAFNRLRKRFLS
>NC_020559|2929429:2967701|2956881_2957073_+|WP_003912823.1|DBSCAN-SWA
MRRYRERLRQRGLRPIQIWVPDVNAPEFVGEAHRPSALVAAREYEDDDQAFVDAVSVDWDDAT
>NC_020559|2929429:2967701|2959803_2960268_+|WP_003900539.1|DBSCAN-SWA
MLQPIGVTPDRRLVFGQRRLEAARLLGWERIPVHVCHTIADVVDRAKAERSENTLRKDFTPSELLAAGRRIAELERPKAKQRQREGGDHGRQARYSGLGSMEPKPESERDAHKADTAISEALGISRGHYQRLKRIDNATRSEAGYRDGLNGWSG
>NC_020559|2929429:2967701|2934674_2935352_+|WP_003901437.1|DBSCAN-SWA
MDPVRRQLYQFVCSQSMPVSRDQAADAVGIPRHQAKFHLDRLTAEGLLDTEYARLTGRSGPGAGRTAKLYRRAGRDIALSLPQREYELAGRLMAAAIVLSATTGEPTVEVLNRIAHDYGQAMGAAATTRPPADPAAALELTLDVLRKYGYEPRRPAGPGDDEVELVNCPFHALAREQTELACNMNHALITGVADALAPHSPAVRLAPGPARCCVVLKRCSAHDPE
>NC_020559|2929429:2967701|2954773_2955154_+|WP_003899407.1|DBSCAN-SWA
MSNLHPLPEVASCVVAPLVREPLNPPAAAEMAARFKALADPVRLQLLSSVASRAGGEACVCDISAGVEVSQPTISHHLKVLRDAGLLTSRRRASWVYYAVVPEALTVLSNLLSVHADAAPALGAPA
>NC_020559|2929429:2967701|2936876_2937698_+|WP_003413589.1|DBSCAN-SWA
MANKRGNAGQPLPLSDRDDDHMQGHWLLARLGKRVLRPGGVELTRTLLARAEVTDADVLELAPGLGRTAAEILARNPRSYVGAESDPNAANLVRHVLAGRGDVRVTDAADTGLSDASADVVIGEAMLTMQGNAAKHTIVAEAARVLRPGGRYAIHELALVPDDVAEQVRTDLRQSLARALKVNARPLTVAEWSHLLAGHGLVVEHVVTASMALLQPRRVIADEGLLGALRFAGNLLIHRAARRRVLLMRHTFRRHRERLTAVAIVAHKPHVDS
>NC_020559|2929429:2967701|2938729_2939548_-|WP_003413594.1|DBSCAN-SWA
MSGRGEPTMKTIIVGIDGSHAAITAALWGVDEAISRAVPLRLVSVIKPTHPSPDDYDRDLAHAERSLREAQSAVEAAGKLVKIETDIPRGPAGPVLVEASRDAEMICVGSVGIGRYASSILGSTATELAEKAHCPVAVMRSKVDQPASDINWIVVRMTDAPDNEAVLEYAAREAKLRQAPILALGGRPEELREIPDGEFERRVQDWHHRHPDVRVYPITTHTGIARFLADHDERVQLAVIGGGEAGQLARLVGPSGHPVFRHAECSVLVVRR
>NC_020559|2929429:2967701|2963871_2964117_-|WP_003899415.1|DBSCAN-SWA
MSGHALAARTLLAAADELVGGPPVEASAAALAGDAAGAWRTAAVELARALVRAVAESHGVAAVLFAATAAAAAAVDRGDPP
>NC_020559|2929429:2967701|2940802_2941234_-|WP_003413598.1|DBSCAN-SWA
MTTARDIMNAGVTCVGEHETLTAAAQYMREHDIGALPICGDDDRLHGMLTDRDIVIKGLAAGLDPNTATAGELARDSIYYVDANASIQEMLNVMEEHQVRRVPVISEHRLVGIVTEADIARHLPEHAIVQFVKAICSPMALAS
>NC_020559|2929429:2967701|2931840_2933226_-|WP_009938541.1|DBSCAN-SWA
MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQHYQAISAQVAAYQQRFVLALSQAGSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAGLIGNGGAGGAGGQGLPFEAGANGGAGGAGGWLFGNGGAGGNGGIGGAGTNLAIGGHGGNGGNAGLIGAGGTGGAGGTGGGEPSAGASGGNGGNGGNGGLLIGNSGDGGAAGNGAGISQNGPASGFGGNGGHAGTTGLIGNGGNGGAGGAGGDVSADFGGVGFGGQGGNGGAGGLLYGNGGAGGNGGAAGSPGSVTAFGGNGGSGGSGGNGGNALIGNAGAGGSAGAGGNGASAGTAGGSGGDGGKGGNGGSVGLIGNGGNGGNGGAGSLFNGAPGFGGPGGSGGASLLGPPGLAGTNGADG
>NC_020559|2929429:2967701|2933570_2934071_+|WP_003413569.1|DBSCAN-SWA
MDLNALADLPLTYPEVGATATGRLPAGYNHLDVSTQIGTGRQRFEQAADAVMHWGMQRNAGLRVRASSETAVVSAVVLVGIAFLRAPCRVVYVIDEPDVRGFGYGTLPGHPVSGEERFAVRCDPMTSVVFAEVLSFSRPATWASKAAGPLGAVTQRFIAQRYLRAV
>NC_020559|2929429:2967701|2962810_2963437_-|WP_003899413.1|terminase|DBSCAN-SWA
MPSPATARPDTATVGERVRAQVLWGVFWHHGIRDPKPGKRRVVLKMGRRGPAPAPAQLKLLGGRSPGRDSGGRRVTPPAAFERVAPECPDWLPPGAKDMWGRVVPELAALNLLKESDLGVLTSFCVAWDQLMQAVTAYREQGFIATNARSRRVTVHPAVAAARAATRDVLVLARELGCTPSAEANLAAVLAAAGDPDDDEFNPFAPDR
>NC_020559|2929429:2967701|2965542_2965935_-|WP_003899417.1|DBSCAN-SWA
MTAVGGSPPTRRCPATEDRAPATVATPSSTDPTASRAVSWWSVHEYVAPTLAAAVEWPMAGTPAWCDLDDTDPVKWAAICDAARHWALRVETCQAASAEASRDVSAAADWPAVSREIQRRRDAYIRRVVV
>NC_020559|2929429:2967701|2954179_2954638_+|WP_003413675.1|DBSCAN-SWA
MSRVQLALNVDDLEAAITFYSRLFNAEPAKRKPGYANFAIADPPLKLVLLENPGTGGTLNHLGVEVGSSNTVHAEIARLTEAGLVTEKEIGTTCCFATQDKVWVTGPGGERWEVYTVLADSETFGSGPRHNDTSDGEASMCCDGQVAVGASG
>NC_020559|2929429:2967701|2931616_2931844_+|WP_003413487.1|DBSCAN-SWA
MGDRYRAGDRVLYGGSMSPKDVDDLATQQDVDDGQSIERRWTGSGQRRWRRSPPTGRYRSNSQIQVWISGAGRLR
>NC_020559|2929429:2967701|2963468_2963792_-|WP_003899414.1|DBSCAN-SWA
MTHKRTKRQPAIAAGLNAPRRNRVGRQHGWPADVPSAEQRRAQRQRDLEAIRRAYAEMVATSHEIDDDTAELALLSMHLDDEQRRLEAGMKLGWHPYHFPDEPDSKQ
>NC_020559|2929429:2967701|2945133_2945673_+|WP_003413614.1|DBSCAN-SWA
MLHRDDHINPPRPRGLDVPCARLRATNPLRALARCVQAGKPGTSSGHRSVPHTADLRIEAWAPTRDGCIRQAVLGTVESFLDLESAHAVHTRLRRLTADRDDDLLVAVLEEVIYLLDTVGETPVDLRLRDVDGGVDVTFATTDASTLVQVGAVPKAVSLNELRFSQGRHGWRCAVTLDV
>NC_020559|2929429:2967701|2962124_2962658_-|WP_003899412.1|head,protease|DBSCAN-SWA
MSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW
>NC_020559|2929429:2967701|2936124_2936799_-|WP_003413588.1|DBSCAN-SWA
MGVSVIIRSLQEPVGRRRAVLRALCASRVPMSIAAIAGKLGVHPNTVRFHLDNLVADGQVERVEPGRGRPGRPPLMFRAVRRTDSTGTRRYRLLAEILASGLAAERDSRAMALSAGRAWGRQLEAPPAGADTEETIDHLVAVLDDLGFAPERRASNGRQQVGLRHCPFLELAETQAGVVCPVHLGIMRGALQTWGAPVTVDRLDAFVEPDLCLAHFTPLEGAIR
>NC_020559|2929429:2967701|2966573_2967701_-|WP_003899420.1|integrase|DBSCAN-SWA
MTQTGKRQRRKFGRIRQFNSGRWQASYTGPDGRVYIAPKTFNAKIDAEAWLTDRRREIDRQLWSPASGQEDRPGAPFGEYAEGWLKQRGIKDRTRAHYRKLLDNHILATFADTDLRDITPAAVRRWYATTAVGTPTMRAHSYSLLRAIMQTALADDLIDSNPCRISGASTARRVHKIRPATLDELETITKAMPDPYQAFVLMAAWLAMRYGELTELRRKDIDLHGEVARVRRAVVRVGEGFKVTTPKSDAGVRDISIPPHLIPAIEDHLHKHVNPGRESLLFPSVNDPNRHLAPSALYRMFYKARKAAGRPDLRVHDLRHSGAVLAASTGATLAELMQRLGHSTAGAALRYQHAAKGRDREIAALLSKLAENQEM
>NC_020559|2929429:2967701|2947149_2947431_-|WP_003413619.1|DBSCAN-SWA
MTDSEHVGKTCQIDVLIEEHDERTRAKARLSWAGRQMVGVGLARLDPADEPVAQIGDELAIARALSDLANQLFALTSSDIEASTHQPVTGLHH
>NC_020559|2929429:2967701|2960677_2962117_-|WP_003899411.1|capsid|DBSCAN-SWA
MTNEQHFADDGDIKQLSLDETRSAAKQLLDSVEGDLTGDVAQRFQALTRHAEELRAEQRRRGREAEEALRRCRAGELRVVPGAPTGGDDGDAPPGNSLRDTAFRTLDVCVRDGLMSSRAAEAAETLCRTGPPQSTSWAQRWLAATGNRDYLGAFVKRVSNPVAGHTTWTDREAAAWREAAAVAAEQRAMGLVDTAGGFLIPAALDPAILLSGDGSTNPIRQVARVVQTTSEVWRGVTSEGAEAHWYSEAQEVSDDSPTLAQPAVPSYRGSCWIPFSLEIEGDAAGFVAEVGRVLADSVEQLQAAAFVSGSGNGEPTGFVSALTGTADYTVTGAGTEAVVAADVYALQSALPPRFQSNSAFAANLSTINVLRQAETANGALKFPSLHASPPMLAGKHIWEVSNMDTVDAAVTATNYPLVLGDWKQFIITDRVGSTVELVPHVFGGNRRPTGQRGFFCWFRVGSDVLVDNAFRVLKVQTTA
>NC_020559|2929429:2967701|2955150_2956647_+|WP_003413686.1|DBSCAN-SWA
MTETVTRTAAPAVVGKLSTLDRFLPVWIGSAMAAGLLLGRWIPGLHTALEGVQLDGISLPIALGLLIMMYPVLAKVRYDRLDTVTGDRKLLLSSLLLNWVLGPALMFALAWLLLADLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAAAVLVALNSIFQVAMFAALGWFYLSVLPGWLGLEQTTIATSPWQIAKSVLIFLGIPLLAGYLSRRIGEKTKGRNWYESRFLPKVGPWALYGLLFTIVILFALQGDQITGRPLDVARIALPLLAYFAIMWVGGYLLGAALRLGYRRTTTLAFTAASNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLALRNRLAGPNATHDADKPSVLFVCVHNAGRSQMAAGLLTHLAGDRIEVRSAGTEPAGQVNPTAVAAMAEMGIDITANAPTLLTGGQVQSSDVVITMGCGDACPYFPGVSYRNWKLPDPAGQPLDVVRMIRDDIADRVQALIAELLATAKTR
>NC_020559|2929429:2967701|2958791_2959790_+|WP_003900538.1|integrase|DBSCAN-SWA
MNTATRVRLARKRADRLNLKLIKNGHHFRLRDADEITLAVGHLGVVEAFLAAAKSQNKPPGPPPSLHAPPSWRRDIDDYLLNLNAAGQRPATIRLRKTVLCAAAHGLGRPPADVTAEHLLDWLGKQQHLSPEGRKTYRSTLRGFFVWAYEMDRVRDYVADSLPKVRCPKQPPRPAGDDVWQAALAKADRRIELMIRLAGEAGLRRAEAAQAHTGDLMDGGLLLVHGKGGKRRIVPISDYLAALIRDTPHGYLFPNGTGGHLTAEHVGKLVSRALPGDATMHTLRHRYATRAYRGSHNLRAVQQLLGHASIVTTERYTALCDDEVRAAAAAAW
>NC_020559|2929429:2967701|2951826_2952483_+|WP_003413654.1|DBSCAN-SWA
MDVEALLQSIPPLMVYLVVGAVVGIESLGIPLPGEIVLVSAAVLSSHPELAVNPIGVGGAAVIGAVVGDSIGYSIGRRFGLPLFDRLGRRFPKHFGPGHVALAERLFNRWGVRAVFLGRFIALLRIFAGPLAGALKMPYPRFLAANVTGGICWAGGTTALVYFAGMAAQHWLERFSWIALVIAVIAGITAAILLRERTSRAIAELEAEHCRKAGTTAA
>NC_020559|2929429:2967701|2948345_2950682_-|WP_009938544.1|DBSCAN-SWA
MSFVIAVPEALTMAASDLANIGSTINAANAAAALPTTGVVAAAADEVSAAVAALFGSYAQSYQAFGAQLSAFHAQFVQSLTNGARSYVVAEATSAAPLQDLLGVVNAPAQALLGRPLIGNGANGADGTGAPGGPGGLLLGNGGNGGSGAPGQPGGAGGDAGLIGNGGTGGKGGDGLVGSGAAGGVGGRGGWLLGNGGTGGAGGAAGATLVGGTGGVGGATGLIGSGGFGGAGGAAAGVGTTGGVGGSGGVGGVFGNGGFGGAGGLGAAGGVGGAASYFGTGGGGGVGGDGAPGGDGGAGPLLIGNGGVGGLGGAGAAGGNGGAGGMLLGDGGAGGQGGPAVAGVLGGMPGAGGNGGNANWFGSGGAGGQGGTGLAGTNGVNPGSIANPNTGANGTDNSGNGNQTGGNGGPGPAGGVGEAGGVGGQGGLGESLDGNDGTGGKGGAGGTAGTDGGAGGAGGAGGIGETDGSAGGVATGGEGGDGATGGVDGGVGGAGGKGGQGHNTGVGDAFGGDGGIGGDGNGALGAAGGNGGTGGAGGNGGRGGMLIGNGGAGGAGGTGGTGGGGAAGFAGGVGGAGGEGLTDGAGTAEGGTGGLGGLGGVGGTGGMGGSGGVGGNGGAAGSLIGLGGGGGAGGVGGTGGIGGIGGAGGNGGAGGAGTTTGGGATIGGGGGTGGVGGAGGTGGTGGAGGTTGGSGGAGGLIGWAGAAGGTGAGGTGGQGGLGGQGGNGGNGGTGATGGQGGDFALGGNGGAGGAGGSPGGSSGIQGNMGPPGTQGADG
>NC_020559|2929429:2967701|2952645_2953092_+|WP_003413657.1|DBSCAN-SWA
MGLITTEPRSSPHPLSPRLVHELGDPHSTLRATTDGSGAALLIHAGGEIDGRNEHLWRQLVTEAAAGVTAPGPLIVDVTGLDFMGCCAFAALADEAQRCRCRGIDLRLVSHQPIVARIAEAGGLSRVLPIYPTVDTALGKGTAGPARC
>NC_020559|2929429:2967701|2944007_2945132_+|WP_003413610.1|DBSCAN-SWA
MRSERLRWLVAAEGPFASVYFDDSHDTLDAVERREATWRDVRKHLESRDAKQELIDSLEEAVRDSRPAVGQRGRALIATGEQVLVNEHLIGPPPATVIRLSDYPYVVPLIDLEMRRPTYVFAAVDHTGADVKLYQGATISSTKIDGVGYPVHKPVTAGWNGYGDFQHTTEEAIRMNCRAVADHLTRLVDAADPEVVFVSGEVRSRTDLLSTLPQRVAVRVSQLHAGPRKSALDEEEIWDLTSAEFTRRRYAEITNVAQQFEAEIGRGSGLAAQGLAEVCAALRDGDVDTLIVGELGEATVVTGKARTTVARDADMLSELGEPVDRVARADEALPFAAIAVGAALVRDDNRIAPLDGVGALLRYAATNRLGSHRS
>NC_020559|2929429:2967701|2943298_2943661_+|WP_003899403.1|DBSCAN-SWA
MSTQRPRHSGIRAVGPYAWAGRCGRIGRWGVHQEAMMNLAIWHPRKVQSATIYQVTDRSHDGRTARVPGDEITSTVSGWLSELGTQSPLADELARAVRIGDWPAAYAIGEHLSVEIAVAV
>NC_020559|2929429:2967701|2947575_2948061_-|WP_003413625.1|DBSCAN-SWA
MNAYDVLKRHHTVLKGLGRKVGEAPVNSEERHVLFDEMLIELDIHFRIEDDLYYPALSAAGKPITGTHAEHRQVVDQLATLLRTPQRAPGYEEEWNVFRTVLEAHADVEERDMIPAPTPVHITDAELEELGDKMAARIEQLRGSPLYTLRTKGKADLLKAI

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003413486.1|2929429_2931508_-|tRNA	threonine--tRNA ligase	A0A2K9L6B6	Tupanvirus	2.5e-104	34.9
WP_003413487.1|2931616_2931844_+	hypothetical protein	NA	NA	NA	NA
WP_009938541.1|2931840_2933226_-	PE family protein	NA	NA	NA	NA
WP_003413569.1|2933570_2934071_+	DUF1990 family protein	NA	NA	NA	NA
WP_003413574.1|2934087_2934528_-	DoxX family membrane protein	NA	NA	NA	NA
WP_003901437.1|2934674_2935352_+	transcriptional regulator	NA	NA	NA	NA
WP_003413583.1|2935336_2935690_-	cupin domain-containing protein	NA	NA	NA	NA
WP_003413586.1|2935702_2936128_-	hypothetical protein	NA	NA	NA	NA
WP_003413588.1|2936124_2936799_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003413589.1|2936876_2937698_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_003413592.1|2937833_2938727_+	universal stress protein TB31.7	NA	NA	NA	NA
WP_003413594.1|2938729_2939548_-	universal stress protein	NA	NA	NA	NA
WP_003899401.1|2939562_2940744_-|protease	site-2 protease family protein	NA	NA	NA	NA
WP_003413598.1|2940802_2941234_-	hypoxic response protein Hrp1	A0A2I6B2H4	Macacine_betaherpesvirus	1.9e-75	100.0
WP_003899402.1|2941747_2942989_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_003899403.1|2943298_2943661_+	hypothetical protein	NA	NA	NA	NA
WP_003413610.1|2944007_2945132_+	hypothetical protein	NA	NA	NA	NA
WP_003413614.1|2945133_2945673_+	archease	NA	NA	NA	NA
WP_010924557.1|2945812_2947111_+	RtcB family protein	A2RQD0	Archaeal_BJ1_virus	3.8e-90	43.3
WP_003413619.1|2947149_2947431_-	DUF1876 domain-containing protein	NA	NA	NA	NA
WP_003413625.1|2947575_2948061_-	non-heme di-iron catalase	NA	NA	NA	NA
WP_003908019.1|2948087_2948342_-	hypothetical protein	NA	NA	NA	NA
WP_009938544.1|2948345_2950682_-	PE family protein	NA	NA	NA	NA
WP_003899405.1|2950710_2950953_+	hypothetical protein	NA	NA	NA	NA
WP_003899406.1|2950953_2951631_+	membrane protein	NA	NA	NA	NA
WP_003413654.1|2951826_2952483_+	DedA family protein	NA	NA	NA	NA
WP_003413657.1|2952645_2953092_+	anti-sigma factor antagonist	NA	NA	NA	NA
WP_003413663.1|2953266_2953599_-	YnfA family protein	NA	NA	NA	NA
WP_015456416.1|2953718_2954078_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003413675.1|2954179_2954638_+	glyoxalase/bleomycin resistance/dioxygenase family protein	NA	NA	NA	NA
WP_003899407.1|2954773_2955154_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003413686.1|2955150_2956647_+	ACR3 family arsenite efflux transporter	A0A2H4PQT9	Staphylococcus_phage	5.1e-14	39.7
WP_003912823.1|2956881_2957073_+	antitoxin MazE family protein	NA	NA	NA	NA
2958230:2958257	attL	NA	NA	NA	NA
WP_003899409.1|2958363_2958795_+	hypothetical protein	NA	NA	NA	NA
WP_003900538.1|2958791_2959790_+|integrase	tyrosine-type recombinase/integrase	A0A2D1G8E2	Mycobacterium_phage	7.4e-62	47.8
WP_003900539.1|2959803_2960268_+	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_003908028.1|2960255_2960507_+	hypothetical protein	NA	NA	NA	NA
WP_003899411.1|2960677_2962117_-|capsid	phage major capsid protein	A0A1B3AYS4	Gordonia_phage	1.4e-66	40.6
WP_003899412.1|2962124_2962658_-|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	3.1e-06	32.9
WP_003899413.1|2962810_2963437_-|terminase	phage terminase small subunit P27 family	V9H0V4	Actinophage	1.6e-17	47.2
WP_003899414.1|2963468_2963792_-	type II toxin-antitoxin system toxin	NA	NA	NA	NA
WP_003899415.1|2963871_2964117_-	type II toxin-antitoxin system antitoxin	NA	NA	NA	NA
WP_003899416.1|2964113_2965541_-	DUF3631 domain-containing protein	NA	NA	NA	NA
WP_003899417.1|2965542_2965935_-	DUF2742 domain-containing protein	NA	NA	NA	NA
WP_003899418.1|2965931_2966192_-	helix-turn-helix domain-containing protein	A0A2P1CHK7	Mycobacterium_phage	3.0e-15	64.6
WP_003900543.1|2966208_2966571_-	hypothetical protein	NA	NA	NA	NA
WP_003899420.1|2966573_2967701_-|integrase	site-specific integrase	A0A1X9SFC1	Mycobacterium_phage	1.5e-66	40.4
2967854:2967881	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_020559|3086894:3112923|DBSCAN-SWA
GTCACGCGACTTGCACCCCGTCTCGGGGTTGTTCGGCAGCCTTGCGGCTGCTTCCCTTCCGCGCTTCACGGCCACCAGCCCGGCCAGGCCGGGTCTTACGGTCGGCTCCACGCTTGACGGCGGCCCCAACTGGGCCGACGACGCTACTGGTGTCCTCGTAGCGTGCGAGGTTGATCGCTGCGCAGTCATCACGCTGATGCGATGCCGAGCACGAATCGCATTGCCAGTGCTCGGCCCATCCGATCTCTTGGACATGCCCGCAGACGTGGCAGGTTTTCGACGATGGGAACCAGCGGTCAGCGACCACTAGTTGTGACCCGTACCAGCCTGTCTTGTAGGACAGGTGGCGGCGCGGGGTGCCCAGGGCCGCGTCGGAGAGTCCGCGCCGGCGAGCGCGGGCACCCGAGAGGCCCTGTTGCCGCAGCATCCCTGCCGCGTCCAGGCCTTCGACAACGATGCGGCCGTGGGTCTTAGCCAAATGCGTTGTCAGACAGTGCAGGTGGTGGGTGCGAACATCGTTGACCCGGCGGTGCAGCCGGGATATTTCGGTGGTGCGCTCACGGTAGCGACGTGAGCCTTTCGTGCAGCGCGACCGTGCCCGGCAGACATGCCGTAGCTCGTTGAGTGCCGCGTCGAGTGGCCGTGGATTCGGCACTCGTTCGAGCACCGCGCCGTCGGCGGTGGCGACCGTGGCCAGGCGGCGCACCCCGACATCAACGCCGACCCGTGAACCGGGGTCGGTCACCTTCGGTTGCTGCGGGCGCTGCACGAGGACCCGCACACTCGCATCGATCCGGGTCCCGTTACGGCGCACCGTGATCGCGAGCACCCGCGACCGGCCTTTGGCGATGAGCCGCTCAACCCGGCGCGTGTTCTCGTGGGTGCGGACGGTCCCGATGACCGGCAGCGTGAGGTGGCGCCGGTCGGGCTCGACGCGCATCGCTCCGGTCGTGAACGTCACCCGGTCTGGGTCGCGTCCCTTCTTCTTAAACCGGGGAAAGCCCATCCTTTTGCCATCACGTTTGCCTGATCGCGAGTTCTGCCAGTTCCAGTACGCGTCGACCGCGCCGTCAATACCGTCGGCGTAGGCCTCCTTCGAGCACTCCGGCCACCACACAACACCGGTCTCGATGTTGACGCACACGTCGTTCTTGACGGTGTTCCAGCGCTTCCGCAACACCCGCAGCGACGGCTTTGCCGTCTGGATCCCGGTCGCCTGCCAGGCGTCGATATCGGCTTTCAGGGTGGCGACGGTCCAGTTGTAGGCCTTGCGGCGGGCACCGAAATGCCGTGCCAACGCGCGGGCCTGCTCGGCGGTCGGATCGAGCGTGAACCGGAAAGCCTGAACCATCCAGCCCTCAGGAATCTCGAATTTCGCCATCAGGCAGCCTCCGACTCTTCGGCGGCGGCCGCCAATGCGCGCTTGGCCCGGTTCTGCGCAGCGCGCTTGCCGTACAGCCGGGCGCACATCGAGGTCAAGATCTCGGTCATGTCCCGTACCAGGTCGTCATCAACCTCGGCCGAGTCGACCACGACCAGCTCGCGGCCTTGGGCGGCCAGCGCCGCTTCGACGTACTCAGAGCCGAACCGGCAGAACCGGTCTCGGTGTTCCACCACGATCCGCTTCACCGATGGGTCACGCAGCAGCGCAAGAAACTTTCGGCGGTGCCCGTTCAGCGCCGAACCGACCTCGGTCACGACCTTGTCGACCGCGATCTGCTCGGTCGTGGCCCAGGCGGTCACCCGCGCCACCTGCCGATCCAGGTCCGGCTTCTGATCCGCTGACGACACTCGCGCATACACGGCCGTCCGCGCCCGGCGGGATCTATCGGCCGGCTGGTCGTCCACGAGAATCAGCCGCCCGGCCTTCCGCGCCGGCACCGGCAACAACCCCGCATGAAACCAGCGATACGCAGTCACCCGCGCAACACCGTTGCGCTCAGCCCACACCGCCAGATTCATACTGTTGTTCCTACAGCACGCCACTGACAACTACCGACCACTCAGACCGCAACAGCTGACAGCCCCTTCCGAATTGAACAGCGGCCCATCGCCGTGCGACGTAGGCCGTGTAGCCCAGTGTGCCACCGTTGCCGTCCCGGACCGCATCCCCCTACATTGAGGCCAGGCTCCAACCGAATCGCCCGGCTCCTCCTCACCCCGCTACCCGGGGTGCATCGTCGCCGGGCGGAGCACCGCCACCGACCTGGTCCGCGAACCCTCGTCACGCAGCAGCGCGATAACCCGGCCGTCGGCGTCACAGGCCGCGTACACGCCGTCGATACCGACCGCCGGCAGGGACCGGCCGTTGGCGGCCGCGCTGGCCTCCGCGGCGGTCAGGTCGCGGCGCGCAAACATCAGCAGGCAGGCCTCATCGAGGCTCAGGCTCAGCGCGGGGCGCTCCGCGAGATCGTCGAGCGATCTCGCCTGGTCCAGCTCGAAGCGGCCGACGCGGGTGCGCCGCAACGCCGTCACATGGCCTCCCACCCCAAGCGCGTCGCCGAGGTCGCGTGCCAACGCGCGGATGTAGGTTCCCGAGGAGCAGTCGATCTCCACATCGATATCGATGAGCTGGTCGCGCCGGCGTGCGGCCAGCAGCTCGAACCGGTCGATGCGGATCGGCCGGGCTTCCAATTGCACGGAGCGCCCCTGGCGGGCCAACCGATAGGCGCGTCGGCCACCGACCTTGATCGCGCTGACCGACGACGGCACCTGCCGGATCTCACCGCGCAGCCGCTCCATCGCGGCGTCGATCGCCTCGATGGTCAGGTGCTTAGCCGGAACCGACTGCAGCACTTGACCTTCGGCGTCCTCGGTGGAAGTGGTCTGACCCAAGCGGATGGTGGCGGCATACGACTTGGGGGCCGCCGTCAGCAGACCGAGGATCTTGGTGGCGCGTTCGATGCCGATCACCAACACCCCGGTGGCCATCGGGTCCAGGGTGCCCGCGTGGCCGACCCGCCGGGTGGCGAAGATGCGGCGGCACCGCCCCACCACGTCATGGCTGGTCATTCCCGCGGGCTTGTCGATAACCACGATTCCGGGGCCGGTTGCGCTCATAGCACGATCGCGGTCAGCACCAGTCCGCGCTCAACCGACCAGCGTCCCCGCAGCGTTGTCAGCGGCGGACCCGACAGGGTGGACCCGTCGATGAGGATACGGGAGACGAAGCGACCCGTCCAGCCGGTGCTATCGGTTTCGAACGTGATGTGCGCGTCCTCGAAACCCAGCCACCTCTTGGTCAGCGGAAACCACGCCTTGTACGTTGCTTCCTTGGCGCAGAACAGGATTCGATCCCAATGCAACGCCGCTGGCATGGTGCGGGGCATGTCGGCGCGCTCGGCCGGCAGGCTGATCGCATCCAGCACACCATTGGGCAACACGTCGTGCGGTTCGGCGTCGATGCCCACGGAACGCACCGCATCCCTGCGTCCGACAACCGCGCCGCGGTAACCGGCGCAGTGGGTGAGGCTACCGACCACGCCGTCGGGCCAGCACGGTTCGCCCTTGTCGCCCTTAAGGATCGGCGCCGGCGGCACACCGAGCTGGTCCAGCGCGATGCGGGCGCAGTGACGCACGGTGATGAATTCGTTGCGCCGCTTGGCAACCGATCGTGCGATCAACGGCGCCTCCTCGGGCAGCGGGGTGAGACCGGGTGGGTCGGAGTACAACTCGGCATACGCCAAATCCTCGAACACGGTCGCCGGCAACACCGACGCCACCAGCGTGCCTACCGTCATCGAGACTGCCGTTGCCGCAATCGTTCCCGGAACTGGGCGGCCTGGGTTCGCATCTCGGGCGTGATCACGAAGTGACCGCCGAAGTCGTTGAGGTAGCCGGGCGCGTATTGGGGATCCGGCAGCACCTGCCGCAGCCAGGAGTAGGGCTTGCGCCGGCGCCACTCCCGCGGGTAACCCACCGACACCTCCTCGAACCGCACACCGTCATACCAGGTGGTGCGGGGAATGTGTAAGTGTCCGTAGACCGAACACACGGCGTTGTAGCGGGTGTGCCAGTCGGCGGTCTTGGTGGTTCCGCACCACAGCGAGAATTCCGGGTAGAACAGCGCGTCGCAGGGCTGTCGCAGCAGCGGAAAGTGGTTGACCAGCACGGTCGGTTGCATCCAGTCGAGCTGTTCGAGACGGGCCCGGGTGGCCGCGACCCGCTCGTGGCACCAGGCGTCGCGGGTGGGGTACGGCTCGGGTGAGAGCAGGAACTCGTCGGTGGCCACGACGTTGCGTTCCTTCGCGATGGCCACACCTTCGGCCTTGCTGTTTGCCCCCTCCGGCAAAAAGCTGTAGTCGTAGAGCAGAAACATCGGCACGATGGTGGCCGGGCCGCCTCGTTCGGTCCATACCGGGAACGGATGCTCGGGTGTGACGACGCCCATCTCGTCGCACATGTTGACCAGATAGTCATAGCGTGCGCGGCCGAAGATCTGCATCGGGTCGCGGTTGGTGGTCCACAGCTCGTGGTTGCCCGGCACCCAGATCACCTTCGCGAACCGCCGCCGCAGCAGGTCCAGCGACCAGCGGATCTCGTCGGTGCGTTCGGCGACGTCGCCGGCGACGATCAGCCAGTCGTCCGGCGAGGACGGGTACAGCGATTCGGCGACGGGTTTGTTGCCGAGGTGACCGGTGTGCAGGTCGGAGATCGCCCACAGCGTCGGCTCGGCGCCGACGGTCTCCTGCCCCGATCCTTTCCAGGTCACGACTTACCACCCTAACGACCCGGCGAAGTGGGAACGAAATCCAGCCAGTTCGACCAACCGCTACGGCGTGAGCAGACGCAAAAGCCCCCATTTCGGGCCCGAAATGGGGGCTTTTGCGTCTGCTCGGCCAACCTAGCCCAACTGCTACGGGGTCGGCGAGGGTTTTGGGGTGTCGGTCCGGCTGATCCGGCAGTCCGACTGTGCGGTGAGGACCGCCGCCTTCTGGGTCGAGCATTTGAACTCGACGCCGCCATGACCGGCGAAGTACACGTCGTGGTCGGCCGGCTTGTTCTTCATCACCCCAAAGCCGGTGGCACCGAACTGTTCGACACCGTCCTTGACGATCTGCACGGCCTGCAGCCACTTGTCGTCGGGGATCGGTCCACTGAAAACGATCATGAAATACGCCGCTTTGGCCCTGGTCCATTCATACTCACCACCGCAGCCGGTCCAGGTGTCCATATCCGTTCGCCACGTCAGGCCGGGCACCAGGGCCGTGATGGCGTTGGCCAGCTGGGTCACCGCCGCCCGGTACTGGTCCTTGGCGTCCTCCAGCGGGGGCTTGGCGCGCAACGGGTTCTCCAGCTCGGCGACCTTCTCCGGGCTCAACGGCCCCTCCTCGCCGGCCCGCGTCCCGTGGCCACTGGGTCCGCACCCAGTCGCCATCACACACACCAGAGCCAGCAGCCACGCCGTCGGCCACCGCATCAACGTCCCCCTCTCAGTGCTGGGCCGGGCGCTGCCGGCATGCCGCCACCCAGAATTGGCGGAAGCAGCGGCGGGCCCACCGTGTTGTCGGGCAGCCCGGCGGCGATCGCCGCCAGGTTATAGCCGGACATCCGCAGCTGCGGCTGGCCGGCGGCATCGAGGAAGGACCGCGGGTAGTCCCCGTGGGCATACACTCCGTCACGCCAGATCCCGCCCGGATCAAAACCCGCCTGTGACGACAGCTCCGTGAACCCGGGGGTCAGATAGGGGTCCAGGCCCCATCCGTGCAGCGGCGCCAACGGCGCCACCAGATTGGTGATGAGGTCGTGGGGGGCCTGCATGACATAAGCGTGCCCGTGATCGAGCCCGAGCTGCGCCGGGCTGTACAGCTCCAAGCCGGGTGAGCCGTAAAACACGACGTCGTTGACCGGATGGGCGCTCTGGGCATCGAGGTCCTGCAACGCCAGCGACGCCGTCAGCGACCCATACGAGTGCCCCAACACGGTCAGGTGGCCACTGGGGTTATTGGCGCGCACCTGCTGCAAATACCGCGACAGATCGGCCGCGCCCGCGTGTGCCTGCCCATCGGTCATGGTCTGCCACAGATCGCCCGCACTGCCGGTGTCGAGTGGGTTCGGGGGCGGGTGGTAGCCCATCCAGGCGATGGTGGCAACCGATGCGGGCTTGCCGGCAGCATTGAGTTGCCGGATTACCTCCGACCGCAGGTCGCGGGCTTCGGTCACCATGCCGGGCAGGGCGCCCCGGGTGGTGGACCCGACGCCGGGAACCGTCACCGACACATTGGCGGCGGTGTCGGGATTACCGACGGCCACGGCCGCCAGCACCTGCTGATTTGGGTCCTCGGGAATCTGCAGCTGGGTCAGGTAGGTCTCGGGTGCTCGGCTCAACGCCTCGTCGACGGCATCGAGCTCACCCAGCCGGCCCCTGGCGGCGCTCAGCTCGTCGGTAAGCGCTGCCAGTCGGCCCACCGCGTCACCGTCGAGGATGCCGTTGTGGTAGTCACGGGCGGCCCGCACACTCAGTTGGTCATACTCCGCCTGTAACCGCTCGAGGTGGGCCTGCAGGCGGGCGCGCTCCTCGCGCAGCCGCTCCTCGTTGGCATCGCTGGCGAGCTGGGTCGGGGTCAGCCCCTCGGGACCGACCGGCGGGCCGGAATCGGCCGGGATGGGCGCGTCACCGTCGGCCATATTGACCGCTGAGGCCAGCTCCTCGTCGACGGCATTGGCCTCGGCCATAATCGCATCCAGCTCCGCCTGCAGCTCCGTTTGCTTGGCCAGCGTCCGCGCCCACTGCGCCTCGGTGGATCGCAGCCCGGGGATCGGCACCACCCGGTTGATCAGCGCATCGATCGTCAGCTCGGCGGCCGCGGCGGCATGGCGTAGTGCGGCCAGCTCGGACTGAACCTTCACAATCCCGTCGGCGGCCCTGTCGGCCGCCCGGGCAACCGCCAACGCCTCGTTGCCGTGGGCGTCGAGGTCTCGGCGAATGCCCGCGTTGTGGTGTGCCGCCGCCTCAGCGGTCTTGCCACCCGAGTTCGCAAAAATCGACAGCGCGGCCAACTGACGCGACGCCTCGAACGTCACCTCCGCTCGGGCACTGGCCGCGTGAAACACCTCCCGGACCGCTTGCGCGTTCCACCGATCGATATCGGCCACGGTCAGTGGCACGAATCACACCCCACGCGGACCAGCTACGACGTCGGCGGAAACACCCACCTGGGCGAGCGCCTGCGCCCGCTCCGCCTCCGCCGCCGCATGCTGGATAGCGGCCTCCTGCAGCCCGAATGCGTGATCACCGATCCTGGTCAGCAGCGCCCTCGACGCGTCCAACCAGTCGTCCATCTTGGCGTTGAGCGCCATCGCCGAGGCGCCCTGCCAGCCGAACTGGGCGGCCTGCATCCGATAGTCCGACGACAAATGTCCGACGGCCAGACCCTCACCCTGCGTGGTCACCTGCGCCGCCGAGTGCATCCACTGCTCCGGACTGATCTGAAACACCCGTTGCTTCCTTGCGTCCATCGAAGTGCATCACATTATGCGTCAGCGGGAACTACCGCAGAATTCACCGCATCAAAGGTGGCCCGGGTTAGAACAAGTTCTCGTTTGACTGTGACGACGCGGAGCCGACTTGTACACTCCCGGCAAGGGACCGCCGAGGGCAGGGGGTGTCGTGTTCACCAGGGTGCGGCTGATCGGAGGGCTCGGTGCGCTGACGGCAGCGGTGGTGGTGGTGGGCACGGTGGGCTGGCAGGGCATCCCCCCAGCGCCGACCGGCGGCGACGCGGTCCAGCTGCGATCGACCGCGGCGCCCATGTCCACCACGATGAAGAGCCCGATCGTGGCGACCACCGACCCCAGCCCGTTTGACCCGTGCCGAGACATCCCGTTCGACGTCATCCAGCGGCTCGGATTGGCCTACACGCCACCGGAAGCCGAGGAGGGGCTGCGCTGCCACTTCGACGCGGGTAACTATCAGATGGCCGTCGAGCCGATCATCTGGCGCACCTACGCCCAGACCCTGCCCCCCGACGCGATCGAGACCACGATCGCCGGCCACCGCGCCGCGCAGTACTGGGTGCGGAAGCCGACGTATCACAACAGCTTCTGGTACTCCTCTTGCATGGTGACCTTCAAGACCAGCTACGGGGTGATCCAGCAGTCGCTGTTCTACTCGACCGTCTACTCCGAGCCCGACGTGGACTGCCCGTCGACCAACCTGCAGCGGGCAAACGACCTCGTCCCCTACTACAGGTTTTAGGTCCCTACCCTGGGCGTCGTGAGTACCACCTCCGCTCGGCCCGAGCGGCCCAAGCTGCGCGCCCTGACCGGACGAGTCGGTGGGCAGGCCCTGGGCGGACTGTTGGGTCTGCCCCGCGCAACCACCCGCTACACCGTCGGTCACGTCCGAGTCCCGATGCGCGACGGCGTCCAGCTGGTGGCCGACCACTACGCACCCGCCACGTCGCAGCCCGTCGGCACCCTGCTGGTGCGTGGGCCATACGGGCGCCGGTTTCCGTTTTCGCTGGTGTTTGCCAGGATTTACGCCGCCCGCGGTTATCACGTCGTGCTGCAGAGCGTGCGCGGGACGTTCGGGTCCGGTGGCGTGTTCGAGCCCATGGTCAACGAGGCCGCCGACGGCGCCGATACGGTGGCGTGGCTGCGTGAACAGCCCTGGTTCACCGGCCGGTTCGGCACCATCGGCCTGCCCTATCTGGGTTTCACCCAGTGGGCGTTGCTGCACGATCCGCCCCCGGAGCTGGCCGCGGCCGTGATCACGGTGGGGCCGCACGACTTCCGGGCCTCGGTGTGGGGCACCGGATCGTTTACGGTCAACGACTTCCTGGGCTGGAGCGATCTGGTTTCCCACCAGGAAGACCCCGGTCGCATCCGGGCCGGAATCCGCCAGCTCACCGCGCCGCGACGGGTGGCGCGGACGGCCGCCACGTTGCCGCTGGGTGAGTCGGCCCGGACGCTGCTCGGCACGGGTGCGCCGTGGTTCGAATCCTGGGTGGAACACACCGACCGCGACGATCCGTTCTGGGACCGACTGCGGTTTCCCGCCGCGTTGGACCGCGTCCAGGTCCCGGTGCTGCTCGTCGGCGGCTGGCAGGACATCTTCCTGCGGCAGACGCTGCAGCAGTACCGGCACCTGCGCGACCGGGGTGTGCACGTCGCGCTGACGGTCGGTCCCTGGACACACACCCAGATGCTCACCAAGGGGCTGGCCACCGGCGCTCGGGAATCGTTGGACTGGTTGGACGCCCACCTCGGCCGGGCGCCGGCGCTGCGCCCCAGCCCGGTGCGGGTCTTCGTCACCAGCCAGGGCTGGCGGCACCTGCCGGACTGGCCTCCGGCGACCACCGAGCGGGCGTGGTACCTGCAGCCCGGTGGCCGCCTGGGTGAGAGCGCTCCGGCTTCCGGCACGCCACCGGCGACGTTTCGCTACCACCCCGCCGACCCGACACCGACCACCGGTGGTCCGCTACTGTCATCCAACGGCGGTTACCGCGACGACAGCCGGCTGGCCACGCGCGCCGATGTGCTGTGCTTCACCGGGGCGCCCCTCACCCACGACCTCTGCGTGCACGGAAACCCCGTCGTCGAGCTGGTGCACAGCTCGGACAACCCCTACGTCGACGTGTTCGTTCGGGTCAGCGAGGTGGACGCGAAGGGCCGGTCCCGCAATGTCAGCGACGGCTACCGGCGCCTTGGTGACGCGCCGGAGCTGGTCCGCGTCGAGCTGGACGCCATCGCCCACCGATTCCGCGCCGACTCCCGCATCCGGGTGCTGATCGCCGGTAGTTGGTTTCCCCGCTATGCGCGAAACCTCGGCACCCCGGAACCGATACTCACCGGACGGCAGCTCAAGCCGGCTACCCACGCGGTGCATTTCGGGCGCTCCCGGCTGCTGCTGCCCGTCGGCTAACGGCTGGTGGTGCGGCGGACCCGGGCGGCGACCCGGCCGATAACCCGAGCCCGTCCAGCGGCGCGTGCCCAGTGGTCTCCCCGACGCGGAACCTGCGAGAGCTACGACCATAAGTCGAGATGCAGTTTCAAAGCCTCATCGAGCTGGGCAAGTTCGGCGGCTGAAACTCGGCCGATTGGCCGGAGCAACCGCTCGGTAGCAATCGATCTGATTTGCTCGGCCTGCGCCTTGCAGTCGACCTGGAGACCAGTAGTGGTGGCCGACAACAACACCTGAAACGGATAGACCTTGGCGATGTTGCTCGTCACCGGCACGACGGTGATGACGCCGCGCCCAAGACGCGTGGCGGTCGCGTTGGCCCGGTCGTTGCTGACGACGACGGCGGGGCGCTGGTTGTTCGCTTCGCTACCTCGAGCGGGGTCGAGATCGACCTGCCAAATCTCACCGCGGCGCATCACCGACTCCGTCGCCGACGGTCTGCTCCCACGCGTCCGTGTCGCCGGCTGCCGACCATTCTTGCCATGCGTTGGCATAGTCATCTTCGAGCGTGGGGTAGCGAAGCACGCGGATCGCATGCTGCAGGCCGGCGGAGCGGGATGGTAATCCCGCTCGTTTCACATATGCGTCCAGGATCGCGACGTCGTCATCGGACAGGCTCACGCTCAACTTCACAACCTAAGATGCTACCAGGGTCGTACCTAGGTAGTAATAGGTTCAGCGGCTGGTCGCGCGCCAGTCGCGCAGCACTTCCTCGACGTGCTCACCCACCCGGTGCCGCGCCGTTTCCCGGTCGACACCCGACATCAGCAGTTCGTCGAACGAAGTGTCGATATGCCGCACCGACGCCGCGACGGCCAGCCTCACCGCTTCGGGATCGAGCGCCCGTCCGGCCGCGCTACGTCCGATCCTGCCGCTGCCGCGGGTGGCCGCGTGGCGGGCGATCGCCTCGGCCCGGCCGGCCGGGCAGTTCGGGAACAGCGTGCGAATCGCGGCGCCGAATTCGGCTTGCAGACGCAGGTCCTCGTTGGCCCGTCGCGCCTCGTCGCGCTCCCGGCGGCGGGCGCGCACCTCCGCATCGGCGAGGCACTCGTTTTCGGCGCGCTCCAGCGCCTCCGCCTCGACCAGGATGCCCTGACGCTCGTATCGCTTACGCGCCCGGCTCCACCGCACCACCACCGCCGAAAGCCGGCTCGCCCGCTTGGCCCGGCGGGTAAGCGCGGCGTCCCCGGACGGCAAGAAGACCAGATGGCCAAGGTCCGCGCAGTCCAGGCACAACGGCCCCGCGTCCTCAAGGAACATCAGGTCACCGCTGCCGCCACACGACGCGCATGACCAGTCGTTGACCGGCATGATCACGACCAAATCGGGGCGCCGGCTCTGCCGCGCGACCGCACGCTCCGAGAGCTCCGGCGACACCCAATGCGTGCGATACGCGCGCTCGATGGCGTCCTCGCCGGTGACGCTGAACCGCAGCCGACGGCGGTCCCGAGTGCGAGCGACGTAATCGGTCTCCGACGGGTTGAGCCCCCGGTCGCGGGCCCAGCGCCGCAACGCGGCCATCACGGCGGTGATCTTGCTGAGGTTGGCCTGTACGACTTGCTCCAGCGAGTCGACGCGGCCCTGCCGCCACTGGTCGACATGCGAGGGCGCCAGCCAGCCCAGGCCGAGCAGCACATCGATCGCGCTGACGAACCGCTGTCGGGCCAGCGCCGCCTGCGCCGCCCGGGCCACCCGCTGCTCCAGAGGTTGACGTGCCATGACCTGCCCGAGCCTAGTCGGACTGCGCACCGAGGCCGCGGAACTGAGTTACTCCGACCAGCCGGACGCGCTCGGAGTGGCGATGCGCGAACGTCGGGAACAACAGAACCTCGTTCGGCCGCCACGGAGAAACGCTTCTCGCCGCATCAACACCGATCAGACGTCGACGAAGTACGTCTACATTACGTACATGCCCGAGACTCTGACTGGTCGCCTCAACTTCCGCCTGTCTCCTGAACAGGAGCAGGCCCTTCGCCACGCCGCCGCGCTCACCGGCCAGAGCCTGTCGGGGTTCGTATTGTCCGCCGCGGTCGACCACGCCCACGATCTCTTGGCCCGGGCCAACCGGATCGAGCTGTCCGAGGCCGCTTTCCGCCGCTTCGTCGCCGCGCTCGACGAGCCCGACGAGGCGGCTCCCGAATTGGTGCGCCTCGCCAGACGGAAGAGCCGCATTCCCCCCCATTGAGCACCCCCGCGCTCGGCCCCGTCGAGCTGTTGGACCCGGACCGGCACGACACGGCGCGCTTCTCCAGCGATGTTGAGGTTCTCGACCACTGGCTGCGCCGAGTCGCGCCCGTCGCGGCTGCCGCCGGCACGGCCGCTACGTGGGTGCTCTGTCGAGGCCGGCGGGTAGTTGGGTTCTACGCGCTCGCCATGGGGAGCATCGAGCGGATCCGGGTGCCATCGCGGCCGGGCCGGGGCCAACCCGACCCGACCCGATCCCAGTGCTCGTCCTCGCTCGCCTGGCGCTCGACCGGCAGGAGCAAGGCACCGGTCTCGGTGGCGATCTTCTCCTCGATGCCCTCATCCGATCCGTGGCCGGTGCCCGGCACTACGGCGCCCGCGCCCTGGTCGTCGACGCCATCGACGACCGCGCCGCCGAGTTCTACGGTCACCACGGCTTCTTGCCCCTCGAGGGTCGACGCCTCTACCGGCGGATCAGCGACATCGCGCGGGCGCTGGGAGTATGAAGCGCTATCGTCGCTTGGCGACGTGCTGCCGATCGATCGCCTCGAATGGCCTCGTTGTTGTTGTCGTCGGTGATGGGGAGGGGCAACGGCAAGATTTTGGATCCGGTGGTGGCCACCACGGGGATGGGCCGCTCGACGGCGCGGCAGATGTTGACCGGCCCGAGGTTGCCGGGCCCGGCCGAGCAGGTCGACGGGCGTAGCCTTCGGCCTCGGGGCTTCAGCGACGAAGCCAGGGCGCTGCTGGAGCACGTGTGGGCCTTGATGGGCATGCCGTGCGGCAAGTACCTGGTGGTCATGCATGACCTGTGGTTGCCGCTGTTGACCGCTGCCGGTGATCTTGACAAGCCGCTCGTCACCGAGGCGTCGGTGGCCGAGTTGAAGGCGACAGCCCTACCAGGGGCGAATCGCATGCCGCACTGGGCCGCAGGGACACTCCCTGATGGCTTTCCAGCCCGGGCGGTGAGGACGCGCACGTGAAAACCAACCCCCGGTACGGCCCGGCGTTCTACTCAGTGATGACGGTGTTGTTCCTGGCGCTGTTCGTGCTAAATGTGTGCACCCACGGCTCGACGCTGGGCCTGATCAGTACCGGAGGCCTCGCCGTGTTGATGGGCTACATCGGCTACCGGGGCTGGTCCGGCAAGCGCCATATCAACCGGCAATAGCGATCATCGACCGGTTCCGGCACACCTGACCAGCGCCGTCGTCGGCCGCCAACCCCACGGCTCGTGTGCCAGCCGACGGTCACCGTGTCGCGGCGGCGGGACACGAGGAAACTGCCCACCAGCCACACCTACTTCGCGCTCACTTTTAAGTGAGGCACTTCGGCATCGAAGGCGGATAAGACCAAGATCCTGGATCGGGTGGTGTCCACCACCGGGATGGGTCGTTCGACGGCCCGGCGGATGCTGACCGGCCCGGGGCTGCCGGAGCCGGCCGAGCAGGTCGACGGGCGCAGGCTGCGGGCGCGGGGCTTCAGTGACGACGCCAGGGCGCTTTTAGAGCACGTGTGGGCCTTGATGGGCATGCCGTGCGGCAAGTACCTGGTGGTGATGCTCGAGCTGTGGCTGCCGCTTGTGGCCGCCGCCGGTGATCTTGACAAGCCGTTCGCCACCGAAGCGGCGGTGGCGGAGTTGAAGGCGATGAGCGCGGCCACCGTGGACCGCTACCTCAAACCCGCCCGCGAGCGGATGCGCATCAAAGGCATCTCGACAACCAAACCCTCACCATTGCTGCGTAATTCGATCACCATCCACACCTGTTCGGATGAGGCGCCCAAGGTCCCGGGGGTGATCGAGGCCGACACTGTGGCGCACTGCGGCCCGAGTCTAATCGGCGAGTTCGCCCGCACCCTGACGATGACTGATCTGGTGACCGGCTGGACCGAGAACGCCTCGATCCGCAACAACGCGGCCAAGTGGATCCTCGAGGGCATCAAGGAGTGCCAGCAGCGGTTCCCATTCCCGATGACGGTTTTCGATTCGGACTGCGGGGGCGAGTTCATCAATCACGACGTCGCCGGCTGGCTGCAGGCCCGCGACATCGCCCAGACTCGCTCGCGGCCGTACCAGAAGAACGACCAGGCCCATGTCGAGTCCAAGAACAATCATGTGGTGCGCAAACACGCGTTCTACTGGCGCTATGACACCGGCGAAGAGCTGGAGCTGCTCAACCGGCTATGGCCGTTGGTGTCGCTGCGGTGCAACTTCTTCACCCCGACCAAAAAGCCCGTCGGCTACACCAGCACCGTCAACGGTCGCCGCAAGCGCATCTATGACAAGCCGGCCACCCCATGGCAGCGCCTGCAGGCATCGGGCGTCCTTGATGCACAGCAACTCTCGACCGTGGCCGCCCGAATCGAAGGCTTCAACCCGGCCGATCTGACCCGCCAGATCAACGCGATCCAAATGCAGCTGCTCGACCTGGCCAAGACCAAGACCGAGGCCCTGGCCACCGCCCGCCACATCGACCTGCAATCATTGCAACCGTCAATCAACCGATTGGCCAAGGCGAAGTAATGCAAGCCCCCCACGCGCTCACTATGCGTGAGGCACCAGCCACGCTTCGCGCTCACTTCTACGTGAGGCACCTCGGATGCTGTTGCGAATCCTGTTGGGCCGCCCCAGTTTAAAGTGGATGAGCTTGGTAGAGGCGCTTACGTGTACGTTGGGAAAGACGCAACAGTGGTCCTAAACAAAGATGGCCAAGTGGTAACCGCCTGGGCGAACAGCCGGGCTGGATGGAGAAATCCGTGAGCAACGTTCTCGATGCTATTTCAACGGAGCACCGTCCCGTGATCGAGCAAGAATTAGAGAATCGTAATCCCGCTCTCTTCGACGAGCTTCGGCGCACAGAGAAGCCAACCAACGAACAGAGCGACGCTGTTATCGACGTGCTTTCCGACGCCTTGATGAAGACCTTTGGACCTGATTGGGTTCCGAATGATTATGGGTTGAAAATCGAACGAGCAATTGACGCATACTTAGAGACGTGGCCGATATACCGATAATCGCTTGACACCAACTATTGCCAGCACCAGGCGCCTACCGTGCATCGGGAGCGCGGCCGGGCTGGTATTCGCGTGGGACTGAAGGAGCTTAGGCAGGAACGCACATGACGTACGCAGCCAGGGACGATACGACGCTCCCCAAACTGCTCGCACAGATGCGGTGGGTGGTGCTGGTGGACAAGCGTCAGCTCGCGGTGCTGCTGCTAGAGAACGAGGGACCGGTCGCTTCCGCGACGGACACGTTGGATACGCGCGGTGATAGCGACTATGAAAACCAGCCGGTCGACGCAGTGGAGCGGCTATGTCGGCGTTTGGCTGACCAGGCGGTGCGTCAGTGGGGTTTTATGCAGGGCCTCAAGCAGAAGCTCGGACCAGGTGTCGACGTGCGGATGAAGCTGGTGGAGTGGAACCGATGAGCTTTAATGGCTCTTCCGGAATCAGAGTGCATGGATCAGCTGAGCCAGGTTGCCGCAGTGCAGTAGTGAACGGATTCGGTAGTGGGTGAGGTTTCTGAATCCGAGGGCGTTACGGCATAGGGCTTCCAGTCGTCCGTTGATGGCTTCGGTGGGCCCGTTGGACGCGTGGTGGTCGAAGTAGGCCAGCACATCGTGGCGGCAGCGCCACAGGGTGCGGCCTAGTTTGGCCAGTTCCTCTAGTACGACAGGGACACCGGTTCCGGCGCTGACGGTGAGCAGCGCGGGGGCTTGCCGTACCCGGGTTTGTTGTTTGTAGTGCCGGGGCGGCTCGGTGATCAGGTCATTGGTAGGCGACGGCCCTCCCGTCGTCTCTTGCCGGAGTGCTACGGGAGGGCCGCCTGTGTGCGCTTGGAGGCGCAGTGGTCACCGTAGAAGCAGATGTCGATCAAGTCGAGCGTCGGCTGGCGGCCGGTGAGCTGAGCTGCCCGTCTTGCGGGGGTGTGCTGGCGGGCTGGGGCCGGGCTCGGTCGCGGCAGTTACGCGGCCCGGCTGGTCCGGTGGAGTTGTGCCCGCGTCGGTCGCGGTGCACCGGGTGCGGGGTGACGCATGTGTTGTTGCCGGTGAGCGCGTTGCTGCGCCGCGCCGACACGGCGGCGGTGATCGTGTCGGCGCTGGCGGCGAAGGCCACCAGCCGGGTCGGGTTCCGCCGGATCGCCACGGATGTGGCTCGCCCGGCGGAGACGGTGCGGGGCTGGCTGCGCCGGTTTGCCGAGCGTGTCGAGGCGGTGCGGTCGGTGTTCACGGTGTGGCTGTGCGCGGTCGATGCCGATCCGGTGATGCCGGATGCAGGTGGCGGCGGGTTCGTCGATGCGGTGGTGGCGATCGGCGCGCTCGCAGCTGCCATCGGGCGCCGGTTTTCGCTGCCCACGGTGTCGCTGGCTGAGACCGCGGTAGCGGTGTCAGGTGGGCGGTTGTTGGCGCCGGGCTGGCCCGGCGAGTGGGTGCAACACGAGTCGACCCTGCCGTAGCCGTCGATCGGGCCGTAAACCTGTGCGCTGTCGTGTGTTTTGACAGACAGCAAATGGAAAGGAGCGGCCGGTGGCGGTCGGCGATGACGAGGAGAAGGTGCGCGCGGAGCGCGCGAGGGCGATCGGGTTGTTTCGCTACCAGTTGATTTGGGAGGCCGCCGATGCGGCGCATTCCACCAAGCAGCGGGGAAAGATGGTGCGCGAGTTGGCCTCACGCGAGCACACCGATCCGTTCGGGCGGCGGGTGCGCATCAGCCGCCAAACCATCGACCGCTGGATCCGGGGCTGGCGGGCCGGCGGGTTCGACGCGCTGGTGCCCAACCCACGCCAGTGCACACCGCGTACCCCGGCCGAGGTGCTGGAGCTGGCGGTGGCGCTGCGGCGGGAAAACCCGCAGCGCACGGCGGCGGCAATCCGGCGGATCCTGCGTACCCAGTTGGGCTGGGCGCCCGATGAACGCACCCTGCAACGCAACTTCCACCGGCTCGGGCTCACCGGCGCCACCACCGGGTCGGCGCCGGCGGTGTTCGGCCGGTTCGAAGCCGAGCACCCGAACGCCCTGTGGACCGGGGATGTGTTGCACGGCATACGGATTGATCTCCGCAAGACCTATCTGTTCGCGTTCTTAGACGACCATTCCCGGTTGGTGCCCGGCTACCGGTGGGGCCATGCCGAGGACACGGTGCGGCTGGCCGCCGCACTGCGCCCGGCGCTGGCCTCCCGCGGCGTGCCCAACGCGGTGTATGTCGATAACGGCTCGCCCTATGTGGATGCGTGGTTGTTGCGGGCATGCGCGAAACTCGGTGTGCGCCTTGTTCATTCCACGCCAGGTCGGCCGCAAGGCAGGGGCAAGATAGAGAGGTTCTTCCGCACCGTGCGCGAGCAGTTCCTGGTCGAGATCACCGGCGAACCCGACGTCGTCGGCCGACATTACGTCGCTGATCTGGCCGAGTTGAATCGGCTGTTTACGGCCTGGGTCGAAACGGTTTATCACCGCAGCGTGCATTCCGAAACCGGGCAGACCCCGCTGGCCCGCTGGTCAGCCGGCGGCCCCATCCCGCTGCCCGCCCCCGAGACGCTCACCGAGGCCTTCCTGTGGGAGGAGCACCGCCGCGTGACCAAGACCGCCACCGTCTCGCTGCACGGCAACCGCTACGAGATCGACCCGGCGCTGGTCGGCCGGAAAGTGGAGTTGGTGTTCGACCCGTTCGATTTGACCCGCATCGAGGTGCGGCTGGCCGGCGCGCCGATGGGGCGGGCCATTCCGTATCACATCGGGCGCCATTCACACCCGAAAGCCAAACCCGAAACCCCCACCGCACCGCCCAAACCCAGCGGCATCGACTACGCGCAGTTAATCGAGACCGCGCACGCAGCCGAACTCGCCCGCGGCGTCAACTACACCGCCCTCACCGGGGCTGCCGATCAGATCCCCGGCCAGCTCGACCTGCTCACCGGCCAGGAGGCCCAACCGAAATGATGCACAAACTGATCTCGTATTACGGTTTTTCGCGCATGCCATTCGGCCGCGATCTGGCACCGGGCATGCTGCATCGCCACAGCGCGCACAACGAAGCGGTCGCCCGCATCGGCTGGTGCATCGCCGACCGCCGCATCGGCGTCATCACCGGCGAAGTCGGCGCCGGCAAGACCGTCGCCGTGCGCGCCGCACTAGCGAGCCTGGATCGCAGCCGCCACACCATCATCTACCTGCCCGACCCCACCGTCGGCGTCCAGGGCATCCACCACCGCATCGTCGCCTCGCTCGGCGGACAACCCCTCACCCACCACGCCACCCTGGCCCCACAGGCCGCCGACGCGCTAGCCGCCGAACAAGCCGAGCGCGGACGCACCCCCGTCGTGGTCGTCGAGGAAGCGCACCTGCTCGGCTATGACCAACTGGAGGCGTTGCGGCTCTTGACAAATCACGACCTCGACTCGTCAAGCCCGTTCGCCTGCCTGCTCATCGGCCAACCCACCCTGCGGCGGCGGATGAAACTCGGCGTGCTCGCCGCGCTTGACCAGCGCATCGGACTCCGATATGCCATGCCGCCCATGACCGACACCAACACCGGCAGCTACCTACGCCACCACCTCAAGCTAGCCGGACGCGACGATGCCCTGTTCTCCGACGACGCCATCGGGTTGATCCACCAGACCAGCCGGGGCTACCCCCGCGCGGTCAACAACCTCGCCCTGCAAGCCCTCGTCGCCGCCTTCGCCGCCGACAAGGCCATCGTCGACGAATCCACCACCCGCACCGCCATCGCCGAAGTCACGGCAGACTGAACACCACACCGACACCCCGAACACCACCGACCCCGCCGGACATCTCCCGGCGGGGTCATTTCATGACCAAACGTCCTCACCGTCAACGCCGCCATCATGCTCATCCTGAATGCCGGTCAACAGACGCGGTGGCGACCCAGTCGTCGTAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTCGGGCACGGCCGAAACACCGCGCGAAGGGCGGTTCAAGTTTCCGTCCCCTCTCGTGGTTTTGGGTCTGACGACTGGGAGGATGTCACTCGGACATAGCTGTCATCGGCGGTGTGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGAGGACATGGAGCAGTAGCGTGGCTGTGGTGTGGCGGGCGATATGCGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTGCTGCACCTCCCGCACCCGGTGCGATTCTGCGTCCAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCCGACGACCCCGATAGTCGCGCTCGTCCATGTCCCACCATGAGGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTACCTGATAGAAGCCGGAAAGCTCCGTGCCGTCAGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACAGGGCACTGGACCTGTATGAGGCACAGATGGCGTACTAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCCGGATCGGTTACCCACGCCGATTTACTGGCCATCGTCGGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACTTGCGCGCACAACGCATCCGCCATCCACGGGGCGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTGAAAGGGGGACTGTGGACGAGTTCGCGCTCAAAATGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTTGAACACGCCGATACCTATTTGGTCGGGAGTGATAAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTGACAGGGTGCGGTGGTCGCTGATCGGCTCCCCGAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACTGAACCGCCCCGGTGAGTCCGGAGACTCTCTGATCTGAGACCTCAGCCGGCGGCTGGTCTCTGGCGTTGAGCGTAGTAGGCAGCCTCGAGTTCGACCGGCGGGACGTCGCCGCAGTACTGGTAGAGGCGGCGATGGTTGAACCAGTCGACCCAGCGCGCGGTGGCCAACTCGACATCCTCGATGGACCGCCAGGGCTTGCCGGGTTTGATCAGCTCGGTCTTGTATAGGCCGTTGATCGTCTCGGCTAGTGCATTGTCATAGGAGCTTCCGACCGCTCCGACCGACGGTTGGATGCCTGCCTCGGCGAGCCGCTCGCTGAACCGGATCGATGTGTACTGAGATCCCCTATCCGTATGGTGGATAACGTCTTTCAGGTCGAGTACGCCTTCTTGTTGGCGGGTCCAGATGGCTTGCTCGATCGCGTCGAGGACCATGGAGGTGGCCATCGTGGAAGCGACCCGCCAGCCCAGGATCCTGCGAGCGTAGGCGTCGGTGACAAAGGCCACGTAGGCGAACCCTGCCCAGGTCGACACATAGGTGAGGTCTGCTACCCACAGCCGGTTAGGTGCTGGTGGTCCGAAGCGGCGCTGGACGAGATCGGCGGGACGGGCTGTGGCCGGATCAGCGATCGTGGTCCTGCGGGCTTTGCCGCGGGTGGTCCCGGACAGGCCGAGTTTGGTCATCAGCCGTTCGACGGTGCATCTGGCCACCTCGATGCCCTCACGGTTCAGGGTTAGCCACACTTTGCGGGCACCGTAAACACCGTAGTTGGCGGCGTGGACGCGGCTGATGTGCTCCTTGAGTTCGCCATCGCGCAGCTCGCGGCGGCTGGGCTCCCGGTTGATGTGGTCGTAGTAGGTCGATGGGGCGATCGGCACACCCAGCTCGGTCAGCTGTGTGCAGATCGACTCGACACCCCACCGCAAACCATCGGGGCCCTCGCGGTGGCCCTGATGATCGGCGATGAACCGGGTAATTAGCGTGCTGGCCGGTCGAGCTCGGCCGCGAAGAAAGCCGACGCGGTCTTTAAAATCGCGTTCGCCCTTCGCAATTCGGCGTTGTCCCGCCGCAAGCGCTTCAGCTCAGCGGATTCTTCGGTCGTGGTCCCGGGCCGTGCGCCGGCATCGACCTGCGCCTGGCGCACCCACTTACGCACCGTCTCCGCGCAGCCAACACCAAGTAGACGGGCGACCTCACTGATCGCTGCCCACTCCGAATCGTGCTGACCGCGGATCTCTGCGACCATCCGCACCGCCCGCTCACGCAGCTCCGGCGGGTACCTCCTCGATGAACCACCTGACATGACCCCATCCTTTCCAAGAACTGGAGTCTCCGGACATGCCGGGGCGGTTCAGGGTTTTGGGTCTGACGACTCGCGGCGAGCACGTCTCACCCAGCAGGCGGTGAGGTTGGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACGGACGAGCTGGACCGCATCAGCGATGCTGAGCTGAGGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTTGTCTCAATCGTGCCGTCTGCGGTGACACGCTCCAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTCGACGATTGGGACATCGACATCGACGCGATCGTCGACGAGTTTCCGTCCTCTCTCGGGGTTTTGGGTCTGACGACGTGATCTTCTCTCCTGGCGAGGTCAAGGAAATCGATGTGGAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCACCAGGATCAGCGCCAAGCCAGTTAGCGCAATCCAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTCCCGGACCATCTGCAGCTCGCCCGGGTCCATGCGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCGGAGTCATCCGCGCGGGCCGGCGCGATTGTTGCCGGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTGGCGATTTACGACGCTGACGGGAACTCGTGCGAATGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGATCCGCGAAATTCACTGCGCGTTATTCAAGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCCGAGCCGACCATCCGCGATCACACCGAAAGGGTTGGCGCAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACGTGGGGAGAGGGAATGGCAATGATGGTCGACGAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTCGGACAGCATCTCCCCGGGCGGGCAGCAGATATCCCATGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCGACCCGTGGCCGCCAGGTTGCCGCCGCCGTTGCTCACCTGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCCGGAAGTCAACTAGAGCGGGTGTCGAACGCTGCCCGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACATGCGAATCCGCTGTCAGCACATGGGATTCCGAGTGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTAGGCGGCCCCGGCGAGGCTGGGGGCGGTTTCACGCGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCAGCGCAGACGGCAGCCCCGAGTACTCGCTCTCCTCAGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACAGGCTGAAATTGAAGCCGGAAATGACGACGCATTGGTGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTAAGCCCGCTAATCCCGCACAAGTGGTCAGAAAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACCTGATGATTGGTCGGCGTATGACGTGCTACTGAGGTGTTGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTAGAAGGCGATCACTGGAAGCACGGCGCTTGCGAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTTGGTCAAAAGCTGTCGCCCAAGCATGAGGCAAAAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACACGACTAGGGGAGCGTGATCCAGAGCCGGCGACCCTCTATGGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACGTGCAAGAATTCCGGGTTGCAGTGCAACACGGTTTTAAGTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACTCTATGGACAATTCGTCCAGCGTGTGGTAACAATGCCTGCTGATGATGTCAAAAGAACACAAACTCCTCTGCGCTGACAAGCCGTCCCCTTCCGTAGAACGTAACTGCCGCAACACCTCTTATCTTATAGATCCGGATGTTGTCGCAGTCGATGGCGAAGCGGTCGATACGTGCAACTAGTTTCGCGAGCTGGCCCTTCGTCAGCATCGCTTCGAATGCGGACTCTTGGACGCGATAGCCAAACCCGGCCAGGATCTTCGCAAGTGAAGCCCGCCGCCGGTTGTCGCTGATGTCGTATATTACGAGGACGAACATCTTGCCTATAGTGCCGCTGGACTCGTCCACTTTGAGCGGGAGATTGAAGTACTCCTCACGGCTGCGAGTGGGCATTTAGGCTCCGGATGGCTCGGAGGTGATATCGATATCGACGAGCCGCGACGGGTGCCCGGCTTCGATAACACGCACGAGGCTTTGCAGTTGCAAGTCGAGGGCGTACTGAAAGGTGTATCGGTGAGGATCGCCTTTGATGTAGGTGGCGGTTCGTGCGATTCGATTACCAAAGGCGCGCGCGATGGATCGTGTGGCTTCCCGTGTCGCGAAGACGGCCCCCGTGTCGGAGTTCTTGCTGAAAGCCCGGGTGTCGACCACACCGTCCGCGATCAATCGAAGTACGGTGTCATCGATGATCGGCGCCCGCCATACCTCCATGAGGTCGCTCGCCAACGTTGCGTGCCCTCGTGAATCCTGGTGTAGGAAACCGATATACGCGTTCAGGCTGTGACGCTCGATCGCCCCTATGATGTTCTTGTACAGCAGCGAATAGCCGAGGCTGACCATCGAGTTGAAGGCGTCCAACGGCGGCCGAGTCGAGCGGCCCTGGAATGCGAACTCCTGCGGGACGAGATGCCCCAGCGCGGTGAAGTATGCCTTTGCGGCATTTCCCTCGAACCCGTTCAACTCCGCCAGGGAGCCCGATCGATCGACCCAGGCCAGCGAGTGCTTCATCGTGCGGATGCTCTCAGCAACGTCTTGCCCCGACGTGTGTGCCCGAATCAAGGCCTGCTGATTCAGGATCTTCCTCGACACGATCCGCTTGCTTAACGACAGGCAGAACGCAGGATCGTCGGTGCGGTGAACTTGCTGACGGAGCCGCGGCGCGTATGACACGTCGGGTGTTGAGATCCGGCCCTGGTAGTGGCCGTCGGTCGTGAAGAGCTGGATGTCGCGCTCACGCTTGAGCATCTCAACGATGAAGGGCGTTGTCATCGTCGGCCGCCCAAACAGCGTGATGCCGTCCAGCGTCTCGATCGGATACTGGCTCTCGCCGAGCTCCTCGCTCCACACGATCACCCGGCCGTCGGCAAAGCTGATCCGCGACACGGAGTCCGAGACATACAGCTGCACCATCTTGCGCACCTGTTAGCCCAGCGGTGCCATATCAATCTGCCGGATGATCTCGTCGTTCAACCGGTCATAGAGCGTCAAATCAGCGCCTGTTTCGCGGGCGAGGATCTTCAGCAGTTGTTCTGGGAGAAGGCTGAACCGCCCCGGTGAGTCCGGAGACTCTCTGATCTGAGACCTCAGCCGGCGGCTGGTCTCTGGCGTTGAGCGTAGTAGGCAGTGAACCGCCCCGGTGAGTCCGGAGACTCTCTGATCTGAGACCTCAGCCGGCGGCTGGTCTCTGGCGTTGAGCGTAGTAGGCAGCCTCGAGTTCGACCGGCGGGACGTCGCCGCAGTACTGGTAGAGGCGGCGATGGTTGAACCAGTCGACCCAGCGCGCGGTGGCCAACTCGACATCCTCGATGGACCGCCAGGGCTTGCCGGGTTTGATCAGCTCGGTCTTGTATAGGCCGTTGATCGTCTCGGCTAGTGCATTGTCATAGGAGCTTCCGACCGCTCCGACCGACGGTTGGATGCCTGCCTCGGCGAGCCGCTCGCTGAACCGGATCGATGTGTACTGAGATCCCCTATCCGTATGGTGGATAACGTCTTTCAGGTCGAGTACGCCTTCTTGTTGGCGGGTCCAGATGGCTTGCTCGATCGCGTCGAGGACCATGGAGGTGGCCATCGTGGAAGCGACCCGCCAGCCCAGGATCCTGCGAGCGTAGGCGTCGGTGACAAAGGCCACGTAGGCGAACCCTGCCCAGGTCGACACATAGGTGAGGTCTGCTACCCACAGCCGGTTAGGTGCTGGTGGTCCGAAGCGGCGCTGGACGAGATCGGCGGGACGGGCTGTGGCCGGATCAGCGATCGTGGTCCTGCGGGCTTTGCCGCGGGTGGTCCCGGACAGGCCGAGTTTGGTCATCAGCCGTTCGACGGTGCATCTGGCCACCTCGATGCCCTCACGGTTCAGGGTTAGCCACACTTTGCGGGCACCGTAAACACCGTAGTTGGCGGCGTGGACGCGGCTGATGTGCTCCTTGAGTTCGCCATCGCGCAGCTCGCGGCGGCTGGGCTCCCGGTTGATGTGGTCGTAGTAGGTCGATGGGGCGATCGGCACACCCAGCTCGGTCAGCTGTGTGCAGATCGACTCGACACCCCACCGCAAACCATCGGGGCCCTCGCGGTGGCCCTGATGATCGGCGATGAACCGGGTAATTAGCGTGCTGGCCGGTCGAGCTCGGCCGCGAAGAAAGCCGACGCGGTCTTTAAAATCGCGTTCGCCCTTCGCAATTCGGCGTTGTCCCGCCGCAAGCGCTTCAGCTCAGCGGATTCTTCGGTCGTGGTCCCGGGCCGTGCGCCGGCATCGACCTGCGCCTGGCGCACCCACTTACGCACCGTCTCCGCGCAGCCAACACCAAGTAGACGGGCGACCTCACTGATCGCTGCCCACTCCGAATCGTGCTGACCGCGGATCTCTGCGACCATCCGCACCGCCCGCTCACGCAGCTCCGGCGGGTACCTCCTCGATGAACCACCTGACAT

Protein sequences of DBSCAN-SWA_2

>NC_020559|3086894:3112923|3094003_3094330_-|WP_003414157.1|DBSCAN-SWA
MFQISPEQWMHSAAQVTTQGEGLAVGHLSSDYRMQAAQFGWQGASAMALNAKMDDWLDASRALLTRIGDHAFGLQEAAIQHAAAEAERAQALAQVGVSADVVAGPRGV
>NC_020559|3086894:3112923|3086894_3088274_-|WP_003899482.1|transposase|DBSCAN-SWA
MAKFEIPEGWMVQAFRFTLDPTAEQARALARHFGARRKAYNWTVATLKADIDAWQATGIQTAKPSLRVLRKRWNTVKNDVCVNIETGVVWWPECSKEAYADGIDGAVDAYWNWQNSRSGKRDGKRMGFPRFKKKGRDPDRVTFTTGAMRVEPDRRHLTLPVIGTVRTHENTRRVERLIAKGRSRVLAITVRRNGTRIDASVRVLVQRPQQPKVTDPGSRVGVDVGVRRLATVATADGAVLERVPNPRPLDAALNELRHVCRARSRCTKGSRRYRERTTEISRLHRRVNDVRTHHLHCLTTHLAKTHGRIVVEGLDAAGMLRQQGLSGARARRRGLSDAALGTPRRHLSYKTGWYGSQLVVADRWFPSSKTCHVCGHVQEIGWAEHWQCDSCSASHQRDDCAAINLARYEDTSSVVGPVGAAVKRGADRKTRPGRAGGREARKGSSRKAAEQPRDGVQVA
>NC_020559|3086894:3112923|3099157_3099412_-|WP_003917684.1|DBSCAN-SWA
MTVELGGAVVDGVDDQGAGAVVPGTGHGSDEGIEEKIATETGALLLPVERQASEDEHWDRVGSGWPRPGRDGTRIRSMLPMASA
>NC_020559|3086894:3112923|3094460_3095090_+|WP_003414158.1|DBSCAN-SWA
MYTPGKGPPRAGGVVFTRVRLIGGLGALTAAVVVVGTVGWQGIPPAPTGGDAVQLRSTAAPMSTTMKSPIVATTDPSPFDPCRDIPFDVIQRLGLAYTPPEAEEGLRCHFDAGNYQMAVEPIIWRTYAQTLPPDAIETTIAGHRAAQYWVRKPTYHNSFWYSSCMVTFKTSYGVIQQSLFYSTVYSEPDVDCPSTNLQRANDLVPYYRF
>NC_020559|3086894:3112923|3101738_3101996_+|WP_003899489.1|DBSCAN-SWA
MSNVLDAISTEHRPVIEQELENRNPALFDELRRTEKPTNEQSDAVIDVLSDALMKTFGPDWVPNDYGLKIERAIDAYLETWPIYR
>NC_020559|3086894:3112923|3103510_3104920_+|WP_003414198.1|integrase,transposase|DBSCAN-SWA
MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQRGKMVRELASREHTDPFGRRVRISRQTIDRWIRGWRAGGFDALVPNPRQCTPRTPAEVLELAVALRRENPQRTAAAIRRILRTQLGWAPDERTLQRNFHRLGLTGATTGSAPAVFGRFEAEHPNALWTGDVLHGIRIDLRKTYLFAFLDDHSRLVPGYRWGHAEDTVRLAAALRPALASRGVPNAVYVDNGSPYVDAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFLVEITGEPDVVGRHYVADLAELNRLFTAWVETVYHRSVHSETGQTPLARWSAGGPIPLPAPETLTEAFLWEEHRRVTKTATVSLHGNRYEIDPALVGRKVELVFDPFDLTRIEVRLAGAPMGRAIPYHIGRHSHPKAKPETPTAPPKPSGIDYAQLIETAHAAELARGVNYTALTGAADQIPGQLDLLTGQEAQPK
>NC_020559|3086894:3112923|3095108_3096758_+|WP_003900576.1|DBSCAN-SWA
MSTTSARPERPKLRALTGRVGGQALGGLLGLPRATTRYTVGHVRVPMRDGVQLVADHYAPATSQPVGTLLVRGPYGRRFPFSLVFARIYAARGYHVVLQSVRGTFGSGGVFEPMVNEAADGADTVAWLREQPWFTGRFGTIGLPYLGFTQWALLHDPPPELAAAVITVGPHDFRASVWGTGSFTVNDFLGWSDLVSHQEDPGRIRAGIRQLTAPRRVARTAATLPLGESARTLLGTGAPWFESWVEHTDRDDPFWDRLRFPAALDRVQVPVLLVGGWQDIFLRQTLQQYRHLRDRGVHVALTVGPWTHTQMLTKGLATGARESLDWLDAHLGRAPALRPSPVRVFVTSQGWRHLPDWPPATTERAWYLQPGGRLGESAPASGTPPATFRYHPADPTPTTGGPLLSSNGGYRDDSRLATRADVLCFTGAPLTHDLCVHGNPVVELVHSSDNPYVDVFVRVSEVDAKGRSRNVSDGYRRLGDAPELVRVELDAIAHRFRADSRIRVLIAGSWFPRYARNLGTPEPILTGRQLKPATHAVHFGRSRLLLPVG
>NC_020559|3086894:3112923|3097472_3098516_-|WP_003414172.1|DBSCAN-SWA
MARQPLEQRVARAAQAALARQRFVSAIDVLLGLGWLAPSHVDQWRQGRVDSLEQVVQANLSKITAVMAALRRWARDRGLNPSETDYVARTRDRRRLRFSVTGEDAIERAYRTHWVSPELSERAVARQSRRPDLVVIMPVNDWSCASCGGSGDLMFLEDAGPLCLDCADLGHLVFLPSGDAALTRRAKRASRLSAVVVRWSRARKRYERQGILVEAEALERAENECLADAEVRARRRERDEARRANEDLRLQAEFGAAIRTLFPNCPAGRAEAIARHAATRGSGRIGRSAAGRALDPEAVRLAVAASVRHIDTSFDELLMSGVDRETARHRVGEHVEEVLRDWRATSR
>NC_020559|3086894:3112923|3091748_3092312_-|WP_003900574.1|DBSCAN-SWA
MRWPTAWLLALVCVMATGCGPSGHGTRAGEEGPLSPEKVAELENPLRAKPPLEDAKDQYRAAVTQLANAITALVPGLTWRTDMDTWTGCGGEYEWTRAKAAYFMIVFSGPIPDDKWLQAVQIVKDGVEQFGATGFGVMKNKPADHDVYFAGHGGVEFKCSTQKAAVLTAQSDCRISRTDTPKPSPTP
>NC_020559|3086894:3112923|3089056_3089953_-|WP_003414147.1|tRNA|DBSCAN-SWA
MSATGPGIVVIDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDPMATGVLVIGIERATKILGLLTAAPKSYAATIRLGQTTSTEDAEGQVLQSVPAKHLTIEAIDAAMERLRGEIRQVPSSVSAIKVGGRRAYRLARQGRSVQLEARPIRIDRFELLAARRRDQLIDIDVEIDCSSGTYIRALARDLGDALGVGGHVTALRRTRVGRFELDQARSLDDLAERPALSLSLDEACLLMFARRDLTAAEASAAANGRSLPAVGIDGVYAACDADGRVIALLRDEGSRTRSVAVLRPATMHPG
>NC_020559|3086894:3112923|3088273_3088855_-|WP_003414146.1|transposase|DBSCAN-SWA
MNLAVWAERNGVARVTAYRWFHAGLLPVPARKAGRLILVDDQPADRSRRARTAVYARVSSADQKPDLDRQVARVTAWATTEQIAVDKVVTEVGSALNGHRRKFLALLRDPSVKRIVVEHRDRFCRFGSEYVEAALAAQGRELVVVDSAEVDDDLVRDMTEILTSMCARLYGKRAAQNRAKRALAAAAEESEAA
>NC_020559|3086894:3112923|3089949_3090633_-|WP_003414149.1|DBSCAN-SWA
MTVGTLVASVLPATVFEDLAYAELYSDPPGLTPLPEEAPLIARSVAKRRNEFITVRHCARIALDQLGVPPAPILKGDKGEPCWPDGVVGSLTHCAGYRGAVVGRRDAVRSVGIDAEPHDVLPNGVLDAISLPAERADMPRTMPAALHWDRILFCAKEATYKAWFPLTKRWLGFEDAHITFETDSTGWTGRFVSRILIDGSTLSGPPLTTLRGRWSVERGLVLTAIVL
>NC_020559|3086894:3112923|3110046_3110388_-|WP_003414276.1|DBSCAN-SWA
MPTRSREEYFNLPLKVDESSGTIGKMFVLVIYDISDNRRRASLAKILAGFGYRVQESAFEAMLTKGQLAKLVARIDRFAIDCDNIRIYKIRGVAAVTFYGRGRLVSAEEFVFF
>NC_020559|3086894:3112923|3104916_3105729_+|WP_003899491.1|DBSCAN-SWA
MMHKLISYYGFSRMPFGRDLAPGMLHRHSAHNEAVARIGWCIADRRIGVITGEVGAGKTVAVRAALASLDRSRHTIIYLPDPTVGVQGIHHRIVASLGGQPLTHHATLAPQAADALAAEQAERGRTPVVVVEEAHLLGYDQLEALRLLTNHDLDSSSPFACLLIGQPTLRRRMKLGVLAALDQRIGLRYAMPPMTDTNTGSYLRHHLKLAGRDDALFSDDAIGLIHQTSRGYPRAVNNLALQALVAAFAADKAIVDESTTRTAIAEVTAD
>NC_020559|3086894:3112923|3102831_3103440_+|WP_003414195.1|DBSCAN-SWA
MVTVEADVDQVERRLAAGELSCPSCGGVLAGWGRARSRQLRGPAGPVELCPRRSRCTGCGVTHVLLPVSALLRRADTAAVIVSALAAKATSRVGFRRIATDVARPAETVRGWLRRFAERVEAVRSVFTVWLCAVDADPVMPDAGGGGFVDAVVAIGALAAAIGRRFSLPTVSLAETAVAVSGGRLLAPGWPGEWVQHESTLP
>NC_020559|3086894:3112923|3110388_3111405_-|WP_003414279.1|DBSCAN-SWA
MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHRYTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA
>NC_020559|3086894:3112923|3092311_3094000_-|WP_003414155.1|DBSCAN-SWA
MPLTVADIDRWNAQAVREVFHAASARAEVTFEASRQLAALSIFANSGGKTAEAAAHHNAGIRRDLDAHGNEALAVARAADRAADGIVKVQSELAALRHAAAAAELTIDALINRVVPIPGLRSTEAQWARTLAKQTELQAELDAIMAEANAVDEELASAVNMADGDAPIPADSGPPVGPEGLTPTQLASDANEERLREERARLQAHLERLQAEYDQLSVRAARDYHNGILDGDAVGRLAALTDELSAARGRLGELDAVDEALSRAPETYLTQLQIPEDPNQQVLAAVAVGNPDTAANVSVTVPGVGSTTRGALPGMVTEARDLRSEVIRQLNAAGKPASVATIAWMGYHPPPNPLDTGSAGDLWQTMTDGQAHAGAADLSRYLQQVRANNPSGHLTVLGHSYGSLTASLALQDLDAQSAHPVNDVVFYGSPGLELYSPAQLGLDHGHAYVMQAPHDLITNLVAPLAPLHGWGLDPYLTPGFTELSSQAGFDPGGIWRDGVYAHGDYPRSFLDAAGQPQLRMSGYNLAAIAAGLPDNTVGPPLLPPILGGGMPAAPGPALRGGR
>NC_020559|3086894:3112923|3100350_3101505_+|WP_003899488.1|integrase,transposase|DBSCAN-SWA
MVSTTGMGRSTARRMLTGPGLPEPAEQVDGRRLRARGFSDDARALLEHVWALMGMPCGKYLVVMLELWLPLVAAAGDLDKPFATEAAVAELKAMSAATVDRYLKPARERMRIKGISTTKPSPLLRNSITIHTCSDEAPKVPGVIEADTVAHCGPSLIGEFARTLTMTDLVTGWTENASIRNNAAKWILEGIKECQQRFPFPMTVFDSDCGGEFINHDVAGWLQARDIAQTRSRPYQKNDQAHVESKNNHVVRKHAFYWRYDTGEELELLNRLWPLVSLRCNFFTPTKKPVGYTSTVNGRRKRIYDKPATPWQRLQASGVLDAQQLSTVAARIEGFNPADLTRQINAIQMQLLDLAKTKTEALATARHIDLQSLQPSINRLAKAK
>NC_020559|3086894:3112923|3099559_3099964_+|WP_009938577.1|DBSCAN-SWA
MGRGNGKILDPVVATTGMGRSTARQMLTGPRLPGPAEQVDGRSLRPRGFSDEARALLEHVWALMGMPCGKYLVVMHDLWLPLLTAAGDLDKPLVTEASVAELKATALPGANRMPHWAAGTLPDGFPARAVRTRT
>NC_020559|3086894:3112923|3111661_3112923_-|WP_087902221.1|transposase|DBSCAN-SWA
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_020559|3086894:3112923|3090629_3091604_-|WP_003414151.1|DBSCAN-SWA
MTWKGSGQETVGAEPTLWAISDLHTGHLGNKPVAESLYPSSPDDWLIVAGDVAERTDEIRWSLDLLRRRFAKVIWVPGNHELWTTNRDPMQIFGRARYDYLVNMCDEMGVVTPEHPFPVWTERGGPATIVPMFLLYDYSFLPEGANSKAEGVAIAKERNVVATDEFLLSPEPYPTRDAWCHERVAATRARLEQLDWMQPTVLVNHFPLLRQPCDALFYPEFSLWCGTTKTADWHTRYNAVCSVYGHLHIPRTTWYDGVRFEEVSVGYPREWRRRKPYSWLRQVLPDPQYAPGYLNDFGGHFVITPEMRTQAAQFRERLRQRQSR
>NC_020559|3086894:3112923|3099960_3100152_+|WP_003414184.1|DBSCAN-SWA
MKTNPRYGPAFYSVMTVLFLALFVLNVCTHGSTLGLISTGGLAVLMGYIGYRGWSGKRHINRQ
>NC_020559|3086894:3112923|3097199_3097430_-|WP_003901465.1|DBSCAN-SWA
MKLSVSLSDDDVAILDAYVKRAGLPSRSAGLQHAIRVLRYPTLEDDYANAWQEWSAAGDTDAWEQTVGDGVGDAPR
>NC_020559|3086894:3112923|3106833_3108095_-|WP_087902221.1|transposase|DBSCAN-SWA
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_020559|3086894:3112923|3098706_3098982_+|WP_003911993.1|DBSCAN-SWA
MPETLTGRLNFRLSPEQEQALRHAAALTGQSLSGFVLSAAVDHAHDLLARANRIELSEAAFRRFVAALDEPDEAAPELVRLARRKSRIPPH
>NC_020559|3086894:3112923|3102100_3102412_+|WP_003414190.1|DBSCAN-SWA
MTYAARDDTTLPKLLAQMRWVVLVDKRQLAVLLLENEGPVASATDTLDTRGDSDYENQPVDAVERLCRRLADQAVRQWGFMQGLKQKLGPGVDVRMKLVEWNR
>NC_020559|3086894:3112923|3096859_3097216_-|WP_003414166.1|DBSCAN-SWA
MMRRGEIWQVDLDPARGSEANNQRPAVVVSNDRANATATRLGRGVITVVPVTSNIAKVYPFQVLLSATTTGLQVDCKAQAEQIRSIATERLLRPIGRVSAAELAQLDEALKLHLDLWS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003899482.1|3086894_3088274_-|transposase	transposase	A0A7P9	Microcystis_virus	9.3e-31	30.3
WP_003414146.1|3088273_3088855_-|transposase	IS607-like element IS1602 family transposase	F9VHY9	Thermus_phage	5.0e-18	30.6
WP_003414147.1|3089056_3089953_-|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_003414149.1|3089949_3090633_-	4'-phosphopantetheinyl transferase	NA	NA	NA	NA
WP_003414151.1|3090629_3091604_-	metallophosphoesterase	NA	NA	NA	NA
WP_003900574.1|3091748_3092312_-	hypothetical protein	NA	NA	NA	NA
WP_003414155.1|3092311_3094000_-	hypothetical protein	NA	NA	NA	NA
WP_003414157.1|3094003_3094330_-	hypothetical protein	NA	NA	NA	NA
WP_003414158.1|3094460_3095090_+	DUF3558 family protein	NA	NA	NA	NA
WP_003900576.1|3095108_3096758_+	CocE/NonD family hydrolase	NA	NA	NA	NA
3096773:3096791	attL	NA	NA	NA	NA
WP_003414166.1|3096859_3097216_-	type II toxin-antitoxin system toxin endoribonuclease MazF9	NA	NA	NA	NA
WP_003901465.1|3097199_3097430_-	antitoxin MazE	NA	NA	NA	NA
WP_003414172.1|3097472_3098516_-	DUF2293 domain-containing protein	NA	NA	NA	NA
WP_003911993.1|3098706_3098982_+	DUF1778 domain-containing protein	NA	NA	NA	NA
WP_003917684.1|3099157_3099412_-	hypothetical protein	NA	NA	NA	NA
WP_009938577.1|3099559_3099964_+	hypothetical protein	NA	NA	NA	NA
WP_003414184.1|3099960_3100152_+	hypothetical protein	NA	NA	NA	NA
WP_003899488.1|3100350_3101505_+|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_003899489.1|3101738_3101996_+	hypothetical protein	NA	NA	NA	NA
WP_003414190.1|3102100_3102412_+	hypothetical protein	NA	NA	NA	NA
WP_003414195.1|3102831_3103440_+	hypothetical protein	NA	NA	NA	NA
WP_003414198.1|3103510_3104920_+|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_003899491.1|3104916_3105729_+	ExeA family protein	NA	NA	NA	NA
WP_087902221.1|3106833_3108095_-|transposase	IS3-like element IS987 family transposase	Q8W6R2	Burkholderia_virus	9.6e-83	59.1
WP_003414276.1|3110046_3110388_-	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_003414279.1|3110388_3111405_-	CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_087902221.1|3111661_3112923_-|transposase	IS3-like element IS987 family transposase	Q8W6R2	Burkholderia_virus	9.6e-83	59.1
3121316:3121334	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage
NC_020559.1|WP_009938544.1|2948345_2950682_-|PE-family-protein	2948345_2950682_-	778 aa aa	NA	NA	NA	2929429-2967701	yes

Protein sequences of NC_020559.1|WP_009938544.1|2948345_2950682_-|PE-family-protein

>NC_020559.1|WP_009938544.1|2948345_2950682_-|PE-family-protein
MSFVIAVPEALTMAASDLANIGSTINAANAAAALPTTGVVAAAADEVSAAVAALFGSYAQSYQAFGAQLSAFHAQFVQSLTNGARSYVVAEATSAAPLQDLLGVVNAPAQALLGRPLIGNGANGADGTGAPGGPGGLLLGNGGNGGSGAPGQPGGAGGDAGLIGNGGTGGKGGDGLVGSGAAGGVGGRGGWLLGNGGTGGAGGAAGATLVGGTGGVGGATGLIGSGGFGGAGGAAAGVGTTGGVGGSGGVGGVFGNGGFGGAGGLGAAGGVGGAASYFGTGGGGGVGGDGAPGGDGGAGPLLIGNGGVGGLGGAGAAGGNGGAGGMLLGDGGAGGQGGPAVAGVLGGMPGAGGNGGNANWFGSGGAGGQGGTGLAGTNGVNPGSIANPNTGANGTDNSGNGNQTGGNGGPGPAGGVGEAGGVGGQGGLGESLDGNDGTGGKGGAGGTAGTDGGAGGAGGAGGIGETDGSAGGVATGGEGGDGATGGVDGGVGGAGGKGGQGHNTGVGDAFGGDGGIGGDGNGALGAAGGNGGTGGAGGNGGRGGMLIGNGGAGGAGGTGGTGGGGAAGFAGGVGGAGGEGLTDGAGTAEGGTGGLGGLGGVGGTGGMGGSGGVGGNGGAAGSLIGLGGGGGAGGVGGTGGIGGIGGAGGNGGAGGAGTTTGGGATIGGGGGTGGVGGAGGTGGTGGAGGTTGGSGGAGGLIGWAGAAGGTGAGGTGGQGGLGGQGGNGGNGGTGATGGQGGDFALGGNGGAGGAGGSPGGSSGIQGNMGPPGTQGADG

Self-targetings in the prophage

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_020559_10	Orphan	10.9|2052917|20|NC_020559|CRISPRCasFinder	2052917-2052936	20	2932221-2932240	2

1. spacer 10.9|2052917|20|NC_020559|CRISPRCasFinder matches to NC_020559 position: 2932221-2932240, mismatch: 2

agagcagcccgccggccccg	CRISPR spacer
agagtagcccgccggcgccg	Protospacer
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